mhurhangee/ep-ind-claims huggingface dataset:
A modular smoking system comprising, a carousel module comprising a substantially annular carousel, a plurality of smoking article ports for receiving smoking articles, such that the smoking article extends radially inwards from the carousel, and a plurality of analysis ports, the carousel having an inner surface and an outer surface radially spaced from the inner surface, in which a plurality of identically-dimensioned aerosol-flow channels are definable through the carousel, each aerosol-flow channel extending radially through the carousel between a smoking article port located at the inner surface of the carousel and an analysis port located at the outer surface of the carousel, and at least one aerosol analysis module (100, 110) located radially outwards from the outer surface of the carousel and couplable to an analysis port for analysis of an aerosol generated by a smoking article coupled to a smoking article port.
A foamable polycarbonate composition comprising 5 to 95 wt% of a poly(siloxane) block copolymer comprising a poly(carbonate-siloxane) comprising 50 to 99 wt% of bisphenol A carbonate units and 1 to 50 wt% of dimethylsiloxane units, each based on the weight of the poly(carbonate-siloxane), a poly(ester-carbonate-siloxane) comprising bisphenol A carbonate units, isophthalate-terephthalate-bisphenol A ester units, and 5 to 200 dimethyl siloxane units, or a combination thereof; 5 to 95 wt% of an auxiliary component comprising a poly(alkylene ester), a poly(ester-carbonate), or a combination thereof, and optionally, a homopolycarbonate; optionally, up to 10 wt% of an additive composition, wherein the composition has a glass transition temperature of 140 °C and below measured using differential scanning calorimetry, and wherein a foamed sample of the composition has an average cell size of 10 nanometers to 20 micrometers, determined as indicated in the specification. 5 to 95 wt% of a poly(siloxane) block copolymer comprising a poly(carbonate-siloxane) comprising 50 to 99 wt% of bisphenol A carbonate units and 1 to 50 wt% of dimethylsiloxane units, each based on the weight of the poly(carbonate-siloxane), a poly(ester-carbonate-siloxane) comprising bisphenol A carbonate units, isophthalate-terephthalate-bisphenol A ester units, and 5 to 200 dimethyl siloxane units, or a combination thereof; a poly(carbonate-siloxane) comprising 50 to 99 wt% of bisphenol A carbonate units and 1 to 50 wt% of dimethylsiloxane units, each based on the weight of the poly(carbonate-siloxane), a poly(ester-carbonate-siloxane) comprising bisphenol A carbonate units, isophthalate-terephthalate-bisphenol A ester units, and 5 to 200 dimethyl siloxane units, or a combination thereof; 5 to 95 wt% of an auxiliary component comprising a poly(alkylene ester), a poly(ester-carbonate), or a combination thereof, and optionally, a homopolycarbonate; optionally, up to 10 wt% of an additive composition, wherein the composition has a glass transition temperature of 140 °C and below measured using differential scanning calorimetry, and wherein a foamed sample of the composition has an average cell size of 10 nanometers to 20 micrometers, determined as indicated in the specification.
Composition, preferably pharmaceutical composition, comprising xanthohumol, preferably in a therapeutically effective amount, for (i) use in the treatment and/or prevention of cancer, and/or (ii) use in the treatment and/or prevention of osteoporosis, and/or (iii) use in the treatment and/or prevention of metabolic syndrome, and/or (iv) use in the treatment and/or prevention of diabetes, and/or (v) use in the treatment and/or prevention of cardiovascular disease(s), and/or (vi) use as therapeutic anti-oxidant, and/or (vii) use as detoxifying agent, and/or (viii) use in inhibiting metabolic activation of procarcinogenes, and/or (ix) use as anti-mutagenic and/or anti-genotoxic agent, and/or (x) use as anti-estrogenic and/or estrogenic agent, and/or (xi) use in inducing apoptosis, and/or (xii) use as anti-angiogenetic agent, and/or (xiii) use as anti-inflammatory agent, and/or (xiv) use in inhibiting NF-κB, wherein the composition comprises or consists of (a) a cold or hot extract of coarsely ground or non-ground roasted malt and (b) XN, preferably a hop extract comprising XN, and/or wherein the composition is obtainable or obtained by mixing (a) a cold or hot extract of coarsely ground or non-ground roasted malt and (b) XN or, preferably, a hop extract comprising XN. (i) use in the treatment and/or prevention of cancer, and/or (ii) use in the treatment and/or prevention of osteoporosis, and/or (iii) use in the treatment and/or prevention of metabolic syndrome, and/or (iv) use in the treatment and/or prevention of diabetes, and/or (v) use in the treatment and/or prevention of cardiovascular disease(s), and/or (vi) use as therapeutic anti-oxidant, and/or (vii) use as detoxifying agent, and/or (viii) use in inhibiting metabolic activation of procarcinogenes, and/or (ix) use as anti-mutagenic and/or anti-genotoxic agent, and/or (x) use as anti-estrogenic and/or estrogenic agent, and/or (xi) use in inducing apoptosis, and/or (xii) use as anti-angiogenetic agent, and/or (xiii) use as anti-inflammatory agent, and/or (xiv) use in inhibiting NF-κB,
A method of inducing blood brain barrier properties in iPSC-derived brain microvascular endothelial cells (BMECs) so as to generate an isogenic blood brain barrier model comprising the steps of (a) co-culturing iPSC-derived BMECs with a combination of iPSC-derived astrocytes and iPSC-derived neurons; wherein blood brain barrier properties are induced, and wherein the iPSC-derived astrocytes and iPSC-derived neurons are isogenic to the iPSC-derived BMECs. (a) co-culturing iPSC-derived BMECs with a combination of iPSC-derived astrocytes and iPSC-derived neurons;
A polymeric scaffold of Formula (Ib) wherein the scaffold comprises a polymeric carrier and a protein based recognition-molecule (PBRM) connected to the polymeric carrier via L P2: wherein: the polymeric carrier is PHF having a molecular weight ranging from 30 kDa to 100 kDa; each occurrence of PBRM independently has a molecular weight ranging from 4 kDa to 20 kDa or from 20 kDa to 30 kDa, each occurrence of D is independently a therapeutic agent having a molecular weight of ≤ 5 kDa; L D1 comprises -X-(CH 2) v -C(=O)- with X directly connected to the carbonyl group of in which X is CH 2, O, or NH, and v is an integer from 1 to 6; in contains a biodegradable bond so that when the bond is broken, D is released from the polymeric carrier in an active form for its intended therapeutic effect; in which L D1 is a carbonyl-containing moiety, and the between L D1 and D denotes direct or indirect attachment of D to L D1; is distinct from in in which L P2 is a moiety containing a functional group that is capable of forming a covalent bond with a functional group of a PBRM, and the between L D1 and L P2 denotes direct or indirect attachment of L P2 to L D1; the between L P2 and PBRM denotes direct or indirect attachment of PBRM to L P2; m is an integer from 1 to 1100, m 1 is an integer from 1 to 220, m 2 is an integer from 3 to 100, m 3 is an integer from 0 to 40, m 4 is an integer from 1 to 20, the sum of m 1 and m 2 ranges from 18 to 220, the sum of m 3 and m 4 ranges from 1 to 40, and the sum of m, m 1, m 2, m 3 and m 4 ranges from 220 to 740. the polymeric carrier is PHF having a molecular weight ranging from 30 kDa to 100 kDa; each occurrence of PBRM independently has a molecular weight ranging from 4 kDa to 20 kDa or from 20 kDa to 30 kDa, each occurrence of D is independently a therapeutic agent having a molecular weight of ≤ 5 kDa; L D1 comprises -X-(CH 2) v -C(=O)- with X directly connected to the carbonyl group of in which X is CH 2, O, or NH, and v is an integer from 1 to 6; in contains a biodegradable bond so that when the bond is broken, D is released from the polymeric carrier in an active form for its intended therapeutic effect; in which L D1 is a carbonyl-containing moiety, and the between L D1 and D denotes direct or indirect attachment of D to L D1; is distinct from in in which L P2 is a moiety containing a functional group that is capable of forming a covalent bond with a functional group of a PBRM, and the between L D1 and L P2 denotes direct or indirect attachment of L P2 to L D1; the between L P2 and PBRM denotes direct or indirect attachment of PBRM to L P2; m is an integer from 1 to 1100, m 1 is an integer from 1 to 220, m 2 is an integer from 3 to 100, m 3 is an integer from 0 to 40, m 4 is an integer from 1 to 20, the sum of m 1 and m 2 ranges from 18 to 220, the sum of m 3 and m 4 ranges from 1 to 40, and the sum of m, m 1, m 2, m 3 and m 4 ranges from 220 to 740.
Protective device configured to protect a lidar-type electromagnetic waves emission organ of a motor vehicle, comprising a wall comprising: - at least one defrosting organ, and - at least one layer composed of an anti-scratch coating, - the wall being configured to be crossed by electromagnetic waves of at least one wavelength between 10 nm and 2000 nm, characterized in that the wall comprises: - a thickness less than or equal to 3 mm, preferably between 1.5 mm and 2 mm, - at least one supporting layer comprising a plastic material transparent to said electromagnetic waves, - at least one layer composed of an anti-reflective coating configured to limit a reflection of said electromagnetic waves on the wall. - at least one defrosting organ, and - at least one layer composed of an anti-scratch coating, - the wall being configured to be crossed by electromagnetic waves of at least one wavelength between 10 nm and 2000 nm, - a thickness less than or equal to 3 mm, preferably between 1.5 mm and 2 mm, - at least one supporting layer comprising a plastic material transparent to said electromagnetic waves, - at least one layer composed of an anti-reflective coating configured to limit a reflection of said electromagnetic waves on the wall.
A detergent composition comprising a subtilase variant, the subtilase variant having at least 90% sequence identity to SEQ ID NO:3, preferably at least 95% sequence identity, preferably at least 96% sequence identity, preferably at least 97% sequence identity, preferably at least 98% sequence identity to SEQ ID NO:3, wherein the subtilase variant has a glutamic acid residue in position 101, and wherein the subtilase variant further comprises one or more substitutions selected from L262E,N,Q,D and S156D, wherein the subtilase variant has increased stability in a liquid detergent composition compared to the subtilase having the amino acid sequence of SEQ ID NO:3, and wherein the positions corresponds to the positions of SEQ ID NO:1.
An engine device comprising: a urea mixing pipe which injects urea water into exhaust gas of an engine; an SCR case which removes nitrogen oxides in the exhaust gas of the engine; and an inlet side of the SCR case connected to an outlet side of the urea mixing pipe, wherein the urea mixing pipe is formed by an outer pipe and an inner pipe having a double pipe structure, wherein the SCR case is formed by an inner case body and an outer case body having a double case structure, and an exhaust gas outlet side end portion (187,190) of the inner pipe is provided in a protruding manner in an inner portion of the SCR case (133,29), characterised in that an exhaust gas outlet side end portion (36, 186) of the outer pipe is connected to an exhaust gas inlet of the inner case body, wherein the exhaust gas outlet side end portion (36, 186) of the outer pipe is formed larger in diameter than an inlet opening of the inner case body, and the exhaust gas outlet side end portion (36, 186) of the outer pipe is fixed by welding to an outer peripheral surface of the inner case body (133, 136). a urea mixing pipe which injects urea water into exhaust gas of an engine; an SCR case which removes nitrogen oxides in the exhaust gas of the engine; and an inlet side of the SCR case connected to an outlet side of the urea mixing pipe, wherein the urea mixing pipe is formed by an outer pipe and an inner pipe having a double pipe structure, wherein the SCR case is formed by an inner case body and an outer case body having a double case structure, and an exhaust gas outlet side end portion (187,190) of the inner pipe is provided in a protruding manner in an inner portion of the SCR case (133,29), characterised in that an exhaust gas outlet side end portion (36, 186) of the outer pipe is connected to an exhaust gas inlet of the inner case body, wherein the exhaust gas outlet side end portion (36, 186) of the outer pipe is formed larger in diameter than an inlet opening of the inner case body, and the exhaust gas outlet side end portion (36, 186) of the outer pipe is fixed by welding to an outer peripheral surface of the inner case body (133, 136).
Water-softening device for softening water supplied to an electrical household appliance, comprising: - a first tank for containing substances with water-softening properties, - a second salt-containing tank, having at least one water inlet opening, and - a chamber for containing brine formed as a result of the entry of water into the second tank and the dissolution of the salt contained therein and intended for regenerating said water-softening substances, said chamber being hydraulically connected to the second tank and being provided with a discharge conduit directed towards said first tank, wherein the said discharge conduit is provided with a pump, wherein said second tank and said chamber are formed within a single casing, within which they are separated by a porous partition, said water-softening device being characterized in that said porous partition is horizontally placed, so that said chamber is located below the second tank, and in that said first tank is located at a level higher than the level of said chamber. - a first tank for containing substances with water-softening properties, - a second salt-containing tank, having at least one water inlet opening, and - a chamber for containing brine formed as a result of the entry of water into the second tank and the dissolution of the salt contained therein and intended for regenerating said water-softening substances, said chamber being hydraulically connected to the second tank and being provided with a discharge conduit directed towards said first tank, wherein the said discharge conduit is provided with a pump,
An agent for dyeing and optionally simultaneously lightening human hair, containing at least one cationic compound of formula: in which A represents an optionally substituted benzene ring or an optionally substituted naphthalene ring of general formulas or: in which R 4, R 5, R 6, R 7 represent, independently of one another, a hydrogen atom, a nitro group, a sulfonic acid group, a nitrile group, a halogen atom (chloride, bromide or fluoride), a carbamoyl group, a C 1 -C 6 alkyl sulfonyl group, a sulfamoyl group or a C 1 -C 6 alkoxy group, or A represents one of the heterocycles to shown below in which R 8, R 9 represent, independently of one another, a hydrogen atom, a nitro group, a nitrile group, a halogen atom, a C 1 -C 6 alkyl sulfonyl group, a carbamoyl group, a C 1 -C 6 alkyl group, a C 1 -C 6 alkoxy group or a phenyl group, R 1, R 2, R 3 represent, independently of one another, a hydrogen atom, a C 1 -C 6 alkyl group, a C 2 -C 6 alkenyl group, a C 1 -C 6 alkoxy group, a halogen atom (CI, Br, J or F), a hydroxy group, an amino group, a carboxyl group, a C 1 -C 6 alkylamino group, a C 1 -C 6 dialkylamino group, a nitro group, a nitrile group, a hydroxy-C 1 -C 6 alkyloxy group or an acylamino group, n, m represent, independently of one another, an integer from 1 to 6, X - represents a monovalent anion, preferably halide, hydrogen sulfate, 1⁄2 sulfate, p-benzene sulfonate, p-toluene sulfonate, acetate, tetrafluoroborate, trifluoromethane sulfonate, hexafluorophosphate, methane sulfate or methane sulfonate. A represents an optionally substituted benzene ring or an optionally substituted naphthalene ring of general formulas or: R 4, R 5, R 6, R 7 represent, independently of one another, a hydrogen atom, a nitro group, a sulfonic acid group, a nitrile group, a halogen atom (chloride, bromide or fluoride), a carbamoyl group, a C 1 -C 6 alkyl sulfonyl group, a sulfamoyl group or a C 1 -C 6 alkoxy group, or A represents one of the heterocycles to shown below R 8, R 9 represent, independently of one another, a hydrogen atom, a nitro group, a nitrile group, a halogen atom, a C 1 -C 6 alkyl sulfonyl group, a carbamoyl group, a C 1 -C 6 alkyl group, a C 1 -C 6 alkoxy group or a phenyl group, R 1, R 2, R 3 represent, independently of one another, a hydrogen atom, a C 1 -C 6 alkyl group, a C 2 -C 6 alkenyl group, a C 1 -C 6 alkoxy group, a halogen atom (CI, Br, J or F), a hydroxy group, an amino group, a carboxyl group, a C 1 -C 6 alkylamino group, a C 1 -C 6 dialkylamino group, a nitro group, a nitrile group, a hydroxy-C 1 -C 6 alkyloxy group or an acylamino group, n, m represent, independently of one another, an integer from 1 to 6, X - represents a monovalent anion, preferably halide, hydrogen sulfate, 1⁄2 sulfate, p-benzene sulfonate, p-toluene sulfonate, acetate, tetrafluoroborate, trifluoromethane sulfonate, hexafluorophosphate, methane sulfate or methane sulfonate.
A method of polymerizing olefins, comprising: contacting ethylene and at least one comonomer with a catalyst system to produce a polyolefin polymer that is multimodal, the catalyst system comprising a first catalyst that promotes polymerization of the ethylene into a low molecular weight portion of the polyolefin polymer, and a second catalyst that promotes polymerization of the ethylene into a high molecular weight portion of the polyolefin polymer; wherein the first catalyst and at least a portion of the second catalyst are co-supported to form a commonly-supported catalyst system; and wherein at least a portion of the second catalyst is added as a catalyst trim feed to the catalyst system, wherein a molar amount of the second catalyst added via the catalyst trim feed per gram of the dry commonly-supported catalyst system ranges from 1.8 μmol to 150 μmol. contacting ethylene and at least one comonomer with a catalyst system to produce a polyolefin polymer that is multimodal, the catalyst system comprising a first catalyst that promotes polymerization of the ethylene into a low molecular weight portion of the polyolefin polymer, and a second catalyst that promotes polymerization of the ethylene into a high molecular weight portion of the polyolefin polymer; wherein the first catalyst and at least a portion of the second catalyst are co-supported to form a commonly-supported catalyst system; and wherein at least a portion of the second catalyst is added as a catalyst trim feed to the catalyst system, wherein a molar amount of the second catalyst added via the catalyst trim feed per gram of the dry commonly-supported catalyst system ranges from 1.8 μmol to 150 μmol.
A method of manufacturing an RFID structure, the method comprising: providing an antenna substrate; forming, on the antenna substrate including a carrier foil, a loop antenna assembly having a stand-alone resonant frequency of f 1 which is above or below a standardized reader frequency range, the loop antenna including an antenna track, and at least two contact pads; and providing a shielding layer parallel with a plane defined by the carrier foil such that the loop antenna assembly in combination with the shielding layer has a resonant frequency of f 2 below the standardized reader frequency range and below the stand-alone resonant frequency of f 1, positioning the loop antenna assembly in combination with the shielding layer against a metallic surface such that the loop antenna assembly in combination with the shielding layer and the metallic surface has a resonant frequency within the standardized reader frequency range. providing an antenna substrate; forming, on the antenna substrate including a carrier foil, a loop antenna assembly having a stand-alone resonant frequency of f 1 which is above or below a standardized reader frequency range, the loop antenna including an antenna track, and at least two contact pads; and providing a shielding layer parallel with a plane defined by the carrier foil such that the loop antenna assembly in combination with the shielding layer has a resonant frequency of f 2 below the standardized reader frequency range and below the stand-alone resonant frequency of f 1, positioning the loop antenna assembly in combination with the shielding layer against a metallic surface such that the loop antenna assembly in combination with the shielding layer and the metallic surface has a resonant frequency within the standardized reader frequency range.
Brake actuator for a brake of a track-guided vehicle, in particular for a brake of a running gear of a rail vehicle, comprising an actuation apparatus and an interior, which has a first interior section and a second interior section, which is separated from the first interior section by means of the actuation apparatus, wherein the actuation apparatus comprises an actuation element to which pressure (p) can be applied in the first interior section and a force transmission element that is connected to the actuation element or embodied in one piece with the actuation element and is arranged in the second interior section, these being guided in the interior, wherein the force transmission element can be coupled to a brake link and an actuation force can be transferred from the actuation element to the brake link via the force transmission element, characterised in that the force transmission element has a height that increases as the distance from the actuation element increases, wherein the force transmission element is coupled to the brake link via rollers that are connected to the brake link in a rotatable manner and are able to roll over the force transmission element.
A fluid level probe for use in a tank containing a first fluid and a second fluid forming an interface therebetween, comprising: a probe shaft including a top end and a bottom end; a first float (40,44) carrying a first magnet and a second magnet, the first float (40,44) being slidably disposed for movement along the probe shaft; a second float carrying a first magnet, the second float being slidably disposed for movement along the probe shaft between the first magnet and the second magnet of the first float (40,44) and adapted to float within the first fluid characterized in that there is magnetic repulsion between the first magnet of the first float (40,44) and the first magnet of the second float and also between the second magnet of the first float (40,44,73) and the first magnet of the second float; and the probe further comprises electronics operative to determine a first density of the first fluid adjacent the second float based on spacing between the first magnet of the first float (40,44,73) and the first magnet of the second float and between the second magnet of the first float (40,44) and the first magnet of the second float. a probe shaft including a top end and a bottom end; a first float (40,44) carrying a first magnet and a second magnet, the first float (40,44) being slidably disposed for movement along the probe shaft; a second float carrying a first magnet, the second float being slidably disposed for movement along the probe shaft between the first magnet and the second magnet of the first float (40,44) and adapted to float within the first fluid characterized in that there is magnetic repulsion between the first magnet of the first float (40,44) and the first magnet of the second float and also between the second magnet of the first float (40,44,73) and the first magnet of the second float; and the probe further comprises electronics operative to determine a first density of the first fluid adjacent the second float based on spacing between the first magnet of the first float (40,44,73) and the first magnet of the second float and between the second magnet of the first float (40,44) and the first magnet of the second float.