mhurhangee/ep-ind-claims huggingface dataset:
Compounds of formula, and pharmaceutically acceptable salts thereof wherein R 1 is selected from - H and CH 3; R 2 is selected from - H and linear C 1 -C 4 -alkyl; X is OH or a residue of formula NHR 3 wherein R 3 is selected from - H, OH, C 1 -C 5 -alkyl, C 3 -C 6 -cycloalkyl, C 2 -C 5 -alkenyl, C 1 -C 5 -alkoxy; - straight or branched C 1 -C 6 -alkyl, C 3 -C 6 -cycloalkyl, C 2 -C 6 -alkenyl, C 1 -C 6 - phenylalkyl, substituted with a carboxy (COOH) group; - a residue of formula SO 2 R 4 wherein R 4 is C 1 -C 2 -alkyl, C 3 -C 6 -cycloalkyl, C 1 -C 3 - haloalkyl; Y is a heteroatom selected from: - S, O and N; Z is a residue selected from: - halogen, linear or branched C 1 -C 4 -alkyl, C 2 -C 4 -alkenyl, C 2 -C 4 -alkynyl, C 1 -C 4 -alkoxy, hydroxy, carboxyl, C 1 -C 4 -acyloxy, phenoxy, cyano, nitro, amino, C 1 -C 4 -acylamino, halo-C 1 -C 3 -alkyl, halo-C 1 -C 3 -alkoxy, benzoyl, linear or branched C 1 -C 8 -alkanesulfonate, linear or branched C 1 -C 8 -alkanesulfonamides, linear or branched C 1 -C 8 alkyl sulfonylmethyl; provided that said compounds are not: -2-{4- [(4-trifluoromethyl-1,3-thiazol-2-yl)amino]phenyl} propanoic acid; -2-{4-[(4-methyl-1,3-thiazol-2-yl)amino]phenyl} propanonic acid; -2-{4-[(4-tert-butyl-1,3-thiazol-2-yl)amino]phenyl} propanoic acid; -2-{4-[(4-trifluoromethyl-1,3-oxazol-2-yl)amino]phenyl} propanoic acid; -2-{4-[(4-methyl-1,3-oxazol-2-yl)amino]phenyl} propanoic acid; -2-{4-[(4-trifluoromethyl-1,3-thiazol-2-yl)amino]phenyl} propanamide. - H and CH 3; - H and linear C 1 -C 4 -alkyl; - H, OH, C 1 -C 5 -alkyl, C 3 -C 6 -cycloalkyl, C 2 -C 5 -alkenyl, C 1 -C 5 -alkoxy; - straight or branched C 1 -C 6 -alkyl, C 3 -C 6 -cycloalkyl, C 2 -C 6 -alkenyl, C 1 -C 6 - phenylalkyl, substituted with a carboxy (COOH) group; - a residue of formula SO 2 R 4 wherein R 4 is C 1 -C 2 -alkyl, C 3 -C 6 -cycloalkyl, C 1 -C 3 - haloalkyl; - S, O and N; - halogen, linear or branched C 1 -C 4 -alkyl, C 2 -C 4 -alkenyl, C 2 -C 4 -alkynyl, C 1 -C 4 -alkoxy, hydroxy, carboxyl, C 1 -C 4 -acyloxy, phenoxy, cyano, nitro, amino, C 1 -C 4 -acylamino, halo-C 1 -C 3 -alkyl, halo-C 1 -C 3 -alkoxy, benzoyl, linear or branched C 1 -C 8 -alkanesulfonate, linear or branched C 1 -C 8 -alkanesulfonamides, linear or branched C 1 -C 8 alkyl sulfonylmethyl; -2-{4- [(4-trifluoromethyl-1,3-thiazol-2-yl)amino]phenyl} propanoic acid; -2-{4-[(4-methyl-1,3-thiazol-2-yl)amino]phenyl} propanonic acid; -2-{4-[(4-tert-butyl-1,3-thiazol-2-yl)amino]phenyl} propanoic acid; -2-{4-[(4-trifluoromethyl-1,3-oxazol-2-yl)amino]phenyl} propanoic acid; -2-{4-[(4-methyl-1,3-oxazol-2-yl)amino]phenyl} propanoic acid; -2-{4-[(4-trifluoromethyl-1,3-thiazol-2-yl)amino]phenyl} propanamide.
1. A slip device for gripping tubulars, the device comprising: a housing forming an axial bore; an upper set of slips spaced axially above a lower set of slips, the upper set of slips and the lower set of slips located in the housing; characterised by the device further comprising: a rack and pinion actuator connected to the upper set of slips and the lower set of slips, the rack and pinion actuator radially moving the upper set of slips and the lower set of slips between a retracted position removed from the bore and an extended position to grip a tubular disposed in the bore, wherein all of the upper set of slips and the lower set of slips are in the retracted position or all of the upper set of slips and the lower set of slips are in the extended position. a housing forming an axial bore; an upper set of slips spaced axially above a lower set of slips, the upper set of slips and the lower set of slips located in the housing; characterised by the device further comprising: a rack and pinion actuator connected to the upper set of slips and the lower set of slips, the rack and pinion actuator radially moving the upper set of slips and the lower set of slips between a retracted position removed from the bore and an extended position to grip a tubular disposed in the bore, wherein all of the upper set of slips and the lower set of slips are in the retracted position or all of the upper set of slips and the lower set of slips are in the extended position. a rack and pinion actuator connected to the upper set of slips and the lower set of slips, the rack and pinion actuator radially moving the upper set of slips and the lower set of slips between a retracted position removed from the bore and an extended position to grip a tubular disposed in the bore, wherein all of the upper set of slips and the lower set of slips are in the retracted position or all of the upper set of slips and the lower set of slips are in the extended position.
A cover for an ultrasound probe, comprising: a cap that removably attaches to a head portion of the ultrasound probe; a first coupling component included with the cap and capable of ultrasonically coupling the head portion to a skin surface of a patient; and a second coupling component that removably covers the first coupling component and is capable of ultrasonically coupling the head portion to the skin surface, the first coupling component being adapted for being placed against a patient's skin to perform an ultrasound scan with the second coupling component removed. a cap that removably attaches to a head portion of the ultrasound probe; a first coupling component included with the cap and capable of ultrasonically coupling the head portion to a skin surface of a patient; and a second coupling component that removably covers the first coupling component and is capable of ultrasonically coupling the head portion to the skin surface, the first coupling component being adapted for being placed against a patient's skin to perform an ultrasound scan with the second coupling component removed.
A therapy system for applying electrical signals to a patient's spinal cord region, comprising: a first and a second implantable signal delivery device; and a controller having instructions for directing: first electrical signals to the patient's spinal cord region via the first implantable signal delivery device, wherein the first electrical signals have a first frequency in a first frequency range from 3,000 Hz to 100,000 Hz; and second electrical signals in a second frequency range of up to 1,500 Hz to the patient's spinal cord region via the second implantable signal delivery device,wherein the implantable signal delivery devices are electrically coupled to the controller. a first and a second implantable signal delivery device; and a controller having instructions for directing: first electrical signals to the patient's spinal cord region via the first implantable signal delivery device, wherein the first electrical signals have a first frequency in a first frequency range from 3,000 Hz to 100,000 Hz; and second electrical signals in a second frequency range of up to 1,500 Hz to the patient's spinal cord region via the second implantable signal delivery device,wherein the implantable signal delivery devices are electrically coupled to the controller.
A compound of Formula I wherein X is hydrogen; Y is Q; Q is R 1 and R 11 are independently chosen from hydrogen or alkyl, optionally substituted with 1 or multiple R 8, alternatively, R 1 and R 11 may be taken together to form a 3 - 6 membered saturated or partially saturated carbocyclic or heterocyclic ring, optionally substituted with 1 or multiple R 8, R 2 and R 12 are independently chosen from hydrogen, alkyl, aryl, or alkenyl, each optionally substituted with 1 or multiple R 8, R 3 is methyl; R 4 is chosen from alkyl, aryl, or acyl, each optionally substituted with 1 or multiple R 8, R 6 is chosen from hydrogen, alkoxy, or halo, each optionally substituted with 1 or multiple R 8, R 7 is chosen from hydrogen, -C R 9, or -CH 2 OC R 9; R 8 is chosen from hydrogen, alkyl, aryl, acyl, halo, alkenyl, alkoxy, or heterocyclyl, each optionally substituted with 1 or multiple R 10; R 9 is chosen from alkyl, alkoxy, or aryl, each optionally substituted with 1 or multiple R 8; and R 10 is chosen from hydrogen, alkyl, aryl, acyl, halo, alkenyl, alkoxy, or heterocyclyl, wherein term "alkyl" refers to a branched, unbranched, or saturated cyclic carbon chain and the term "alkenyl" refers to a branched, unbranched or cyclic carbon chain containing one or more double bonds. X is hydrogen; Y is Q; Q is R 1 and R 11 are independently chosen from hydrogen or alkyl, optionally substituted with 1 or multiple R 8, alternatively, R 1 and R 11 may be taken together to form a 3 - 6 membered saturated or partially saturated carbocyclic or heterocyclic ring, optionally substituted with 1 or multiple R 8, R 2 and R 12 are independently chosen from hydrogen, alkyl, aryl, or alkenyl, each optionally substituted with 1 or multiple R 8, R 3 is methyl; R 4 is chosen from alkyl, aryl, or acyl, each optionally substituted with 1 or multiple R 8, R 6 is chosen from hydrogen, alkoxy, or halo, each optionally substituted with 1 or multiple R 8, R 7 is chosen from hydrogen, -C R 9, or -CH 2 OC R 9; R 8 is chosen from hydrogen, alkyl, aryl, acyl, halo, alkenyl, alkoxy, or heterocyclyl, each optionally substituted with 1 or multiple R 10; R 9 is chosen from alkyl, alkoxy, or aryl, each optionally substituted with 1 or multiple R 8; and R 10 is chosen from hydrogen, alkyl, aryl, acyl, halo, alkenyl, alkoxy, or heterocyclyl, wherein term "alkyl" refers to a branched, unbranched, or saturated cyclic carbon chain and the term "alkenyl" refers to a branched, unbranched or cyclic carbon chain containing one or more double bonds.
A data manager for distributing data of a data stream of a user equipment via a first wireless local area network link and a second wireless local area network link, the user equipment being configured to simultaneously communicate over the first wireless local area network link and the second wireless local area network link, the first wireless local area network link connecting the user equipment to a first access gateway, wherein the first access gateway is configured to connect to a first network access entity providing access to a communication network via a first communication link, the second wireless local area network link connecting the user equipment to a second access gateway, wherein the second access gateway is configured to connect to a second network access entity providing access to the communication network via a second communication link, the first wireless local area network link and the first communication link forming a first composite communication link, and the second wireless local area network link and the second communication link forming a second composite communication link, the data manager comprising: a network interface being configured to receive a first status signal indicating a link quality of the first composite communication link, and a second status signal indicating a link quality of the second composite communication link, and a processor being configured to determine a reduction of an amount of data of the data stream communicated over the first wireless local area network link and to determine an increase of an amount of data of the data stream communicated over the second wireless local area network link, if the second status signal indicates a higher link quality than a link quality that is indicated by the first status signal. a network interface being configured to receive a first status signal indicating a link quality of the first composite communication link, and a second status signal indicating a link quality of the second composite communication link, and a first status signal indicating a link quality of the first composite communication link, and a second status signal indicating a link quality of the second composite communication link, and a processor being configured to determine a reduction of an amount of data of the data stream communicated over the first wireless local area network link and to determine an increase of an amount of data of the data stream communicated over the second wireless local area network link, if the second status signal indicates a higher link quality than a link quality that is indicated by the first status signal. to determine a reduction of an amount of data of the data stream communicated over the first wireless local area network link and to determine an increase of an amount of data of the data stream communicated over the second wireless local area network link, if the second status signal indicates a higher link quality than a link quality that is indicated by the first status signal.
A direct current, DC, power supply system for a vehicle, the DC power supply system comprising: a direct current, DC, powered motor coupleable to a rotor; an electronic speed controller coupled to the DC-powered motor to control the speed of the DC-powered motor by regulating electric current supplied to the DC-powered motor; and a genset subsystem (104; 300) coupled to the electronic speed controller to power the electronic speed controller through a DC motor bus, wherein the genset subsystem includes: a battery set including one or more batteries; an alternator having a mechanical movement input and a multiphase alternating current, AC, output; and a motor-gen controller (318; 1000) having a phase control circuit (1100; 1200) configured to rectify the multiphase AC output of the alternator to produce a rectified DC feed to the DC-powered motor, and wherein the motor-gen controller (318; 1000) is configured to draw DC power from the battery set to produce the rectified DC feed, characterised in that the genset subsystem (104; 300) comprises an augmentation controller configured to fill in voltage ripples in the rectified DC feed from the phase control circuit using the DC power from the battery set. a direct current, DC, powered motor coupleable to a rotor; an electronic speed controller coupled to the DC-powered motor to control the speed of the DC-powered motor by regulating electric current supplied to the DC-powered motor; and a genset subsystem (104; 300) coupled to the electronic speed controller to power the electronic speed controller through a DC motor bus, wherein the genset subsystem includes: a battery set including one or more batteries; an alternator having a mechanical movement input and a multiphase alternating current, AC, output; and a motor-gen controller (318; 1000) having a phase control circuit (1100; 1200) configured to rectify the multiphase AC output of the alternator to produce a rectified DC feed to the DC-powered motor, and wherein the motor-gen controller (318; 1000) is configured to draw DC power from the battery set to produce the rectified DC feed, characterised in that the genset subsystem (104; 300) comprises an augmentation controller configured to fill in voltage ripples in the rectified DC feed from the phase control circuit using the DC power from the battery set. a battery set including one or more batteries; an alternator having a mechanical movement input and a multiphase alternating current, AC, output; and a motor-gen controller (318; 1000) having a phase control circuit (1100; 1200) configured to rectify the multiphase AC output of the alternator to produce a rectified DC feed to the DC-powered motor, and wherein the motor-gen controller (318; 1000) is configured to draw DC power from the battery set to produce the rectified DC feed, characterised in that the genset subsystem (104; 300) comprises an augmentation controller configured to fill in voltage ripples in the rectified DC feed from the phase control circuit using the DC power from the battery set.
Assembly (100, 200) for an aircraft, said assembly (100, 200) having a vertical median plane and having: - a nacelle of a jet engine of the aircraft, wherein the nacelle has, on either side of a vertical median plane, a cowl, - a pylon intended to be fastened between the jet engine and a wing of the aircraft, - a heat exchanger (102, 202), and - a support module having a cradle to which the heat exchanger (102, 202) is fastened, characterized in that it comprises: - on either side of the vertical median plane, articulation fittings, called second articulation fittings, fastened to the cowl, - fastening means, wherein the fastening means fasten the cradle to the pylon and above the pylon, - on either side of the vertical median plane, two articulation fittings (104a-b, 204a-b), called first articulation fittings, directly secured to the cradle, wherein each first articulation fitting (104a-b, 204a-b) is associated with one of the second articulation fittings of a cowl so as to form a hinge (107a-b). - a nacelle of a jet engine of the aircraft, wherein the nacelle has, on either side of a vertical median plane, a cowl, - a pylon intended to be fastened between the jet engine and a wing of the aircraft, - a heat exchanger (102, 202), and - a support module having a cradle to which the heat exchanger (102, 202) is fastened, - on either side of the vertical median plane, articulation fittings, called second articulation fittings, fastened to the cowl, - fastening means, wherein the fastening means fasten the cradle to the pylon and above the pylon, - on either side of the vertical median plane, two articulation fittings (104a-b, 204a-b), called first articulation fittings, directly secured to the cradle, wherein each first articulation fitting (104a-b, 204a-b) is associated with one of the second articulation fittings of a cowl so as to form a hinge (107a-b).
Panel (101, 102, 110) for a system for receiving and/or storing liquid, the panel defining a plane and having openings therein for through passage of the liquid, wherein the openings are defined by a plurality of lamellae (112, 113), each lamella being a strip having a longitudinal direction and a width direction extending between first and second opposite longitudinal edges (116, 117) defining a plane of the lamella, wherein a first lamella (113.1) is off set from a second lamella (113.2) in a direction perpendicular to the plane of the lamellae, thereby forming the openings in the panel between the first and second lamellae, and wherein the second longitudinal edge of the first lamella is aligned or partially overlapping with the first longitudinal edge of the second lamella, such that the second longitudinal edge of the first lamella is off set with the first longitudinal edge of the second lamella in the width direction and such that the lamellae form a closed view in the direction perpendicular to the plane of the lamellae.
A TRPV-1 antagonist for use in a method of reducing irritation induced by topical application of phenoxyethanol; said method comprising topically applying a composition comprising phenoxyethanol with said TRPV-1 antagonist; wherein said TRPV-1 antagonist is 4-tertiary butyl cyclohexanol; wherein phenoxyethanol and said TRPV-1 antagonist are present in said composition in a mass ratio of TRPV-1 antagonist to phenoxyethanol of 0.4:24 to 0.6:2.7. said method comprising topically applying a composition comprising phenoxyethanol with said TRPV-1 antagonist; wherein said TRPV-1 antagonist is 4-tertiary butyl cyclohexanol; wherein phenoxyethanol and said TRPV-1 antagonist are present in said composition in a mass ratio of TRPV-1 antagonist to phenoxyethanol of 0.4:24 to 0.6:2.7.
A computer implemented method of classifying tympanic membrane pathologies from images, comprising: capturing one or more images of a tympanic membrane using an image capture device; performing preprocessing in (202, 804) on the captured one or more images; and classifying (208, 806) pathologies of the tympanic membrane using the captured one or more images, wherein classifying (208, 806) pathologies of the tympanic membrane using the captured one or more images comprises extracting computer vision features CVF from the one or more images; extracting clinically meaningful eardrum features CMEF from the one or more images; and classifying (208, 806) pathologies of the tympanic membrane using the CVF and CMEF information fused by a two-layered stacked generalization algorithm that focuses on complementary features instead of strong features, wherein the two-layered stacked generalization algorithm comprises using a Fuzzy Stacked Generalization FSG classifier. capturing one or more images of a tympanic membrane using an image capture device; performing preprocessing in (202, 804) on the captured one or more images; and classifying (208, 806) pathologies of the tympanic membrane using the captured one or more images, wherein classifying (208, 806) pathologies of the tympanic membrane using the captured one or more images comprises extracting computer vision features CVF from the one or more images; extracting clinically meaningful eardrum features CMEF from the one or more images; and classifying (208, 806) pathologies of the tympanic membrane using the CVF and CMEF information fused by a two-layered stacked generalization algorithm that focuses on complementary features instead of strong features, wherein the two-layered stacked generalization algorithm comprises using a Fuzzy Stacked Generalization FSG classifier.
A turbomolecular pump - having a stator with a plurality of stator disks which follow one another in the direction of an axis of rotation and which each have blades; and - having a rotor which is rotatably supported about the axis of rotation relative to the stator and which comprises a rotor shaft and a plurality of rotor disks which are arranged at the rotor shaft, which follow one another in the axial direction, which are arranged between the stator disks and which each have blades, wherein at least one rotor disk bounds a radial sealing gap formed between the rotor disk and the stator; wherein at least one stator-side sealing section is provided which at least partly covers the sealing gap in the axial direction, viewed against the conveying direction, and which is arranged, with respect to the conveying direction, in front of the blades of the stator disk which follows the rotor disk in the conveying direction; and wherein the rotor disk has at least one radial annular prolongation which projects from the blades of the rotor disk in the radial direction, with the radial sealing gap being at least sectionally bounded by the prolongation, characterized in that the prolongation only extends over a portion of the axial extent of the blades of the rotor disk. - having a stator with a plurality of stator disks which follow one another in the direction of an axis of rotation and which each have blades; and - having a rotor which is rotatably supported about the axis of rotation relative to the stator and which comprises a rotor shaft and a plurality of rotor disks which are arranged at the rotor shaft, which follow one another in the axial direction, which are arranged between the stator disks and which each have blades,
A washer for receiving a fastener therethrough, the washer comprising: a core formed of reinforcement fibers supported in a thermoplastic matrix material, wherein said reinforcement fibers comprise carbon fibers; and an electrically-insulating outer layer overlaying the core; wherein said outer layer comprises glass fibers. a core formed of reinforcement fibers supported in a thermoplastic matrix material, wherein said reinforcement fibers comprise carbon fibers; and an electrically-insulating outer layer overlaying the core; wherein said outer layer comprises glass fibers.