mhurhangee/ep-ind-claims huggingface dataset:
Assembly method for a fluid-tight connection device (1, 1') for a circuit carrying a fluid under pressure, the device comprising a polymeric tubular connector (20, 20') which is mounted around a radially outer connection zone (11, 11') of a metal tube (10, 10') included in the device, and which is to be connected to an element of the circuit, the zone having a circumferential swelling against which there is mounted a seal likewise included in the device, the method comprising: a) mounting the seal against this swelling of the tube, b) mutually positioning said connection zone of the tube axially along a radially inner face of the connector, in such a manner that this connection zone is surrounded by an axially central portion of said radially inner face of the connector, and that two end portions (24 and 25, 25') of this connection are mounted on this swelling and on an adjacent end (14, 14') of the tube, respectively, wherein the method then comprises rotational friction welding of this central portion of the connector to this connection zone of the tube, set back from said seal, in order to ensure that the device is fluid-tight and to confine the weld interface radially between the connector and the tube and axially between the seal and said end portion (25, 25') of the connection which is mounted on the adjacent end of the tube, and the method comprises connecting said connector so welded to an element of an air conditioning or power steering circuit for a motor vehicle, and wherein this welding is carried out by mutually rotating the connector about the tube under an axial welding pressure of preferably close to 3.5 bar and then, during a cooling following this rotation, exerting an axial holding pressure of preferably close to 4 bar. a) mounting the seal against this swelling of the tube, b) mutually positioning said connection zone of the tube axially along a radially inner face of the connector, in such a manner that this connection zone is surrounded by an axially central portion of said radially inner face of the connector, and that two end portions (24 and 25, 25') of this connection are mounted on this swelling and on an adjacent end (14, 14') of the tube, respectively,
A computer-implemented method for determining infeasible conditions comprising executing a backward-bounded symbolic analysis on a control flow graph of a dynamic program, wherein executing a backward-bounded symbolic analysis comprises: - defining a reachability condition and a backward bound in the control flow graph, wherein nodes of the control flow graph represent instructions of the dynamic program and branches represent links between instructions, characterised in that the backward-bounded symbolic analysis further comprises performing a reachability analysis on predecessors instructions of the reachability condition, up to the backward bound, and wherein performing a reachability analysis comprises: - determining a set of predecessors of the reachability condition back to the backward bound; - generating a symbolic representation of the set of predecessors; and - executing an emptiness-check over said symbolic representation to determine emptiness or not of the set of predecessors. - defining a reachability condition and a backward bound in the control flow graph, wherein nodes of the control flow graph represent instructions of the dynamic program and branches represent links between instructions, - determining a set of predecessors of the reachability condition back to the backward bound; - generating a symbolic representation of the set of predecessors; and - executing an emptiness-check over said symbolic representation to determine emptiness or not of the set of predecessors.
An oligonucleotide modified by substitution at the 5' or the 3' end by a lipid moiety,, of the general formula wherein: • Oligo represents a nucleic acid sequence of at least 10 nucleotides, said nucleic acid sequence including a series of at least 4 consecutive guanine residues located in the middle of said sequence, i.e. wherein the series of guanine residues is not located at the 5' end or at the 3' end of the nucleic acid sequence, and is separated from each end of the nucleic acid sequence by a number of nucleotides corresponding to at least 25% of the total number of nucleotides of the nucleic acid sequence, the number of nucleotides separating the series of guanine from the 5' end and the 3' end of the nucleic acid sequence being identical or different, wherein said nucleic acid sequence may be oriented 3'-5' or 5'-3' and/or may comprise modified nucleotides; • Y represents a divalent linker moiety selected from ether -O-, thio - S-, amino -NH-, and methylene -CH 2 -; • R 3 and R 4 may be identical or different and represent: ∘ a hydrogen atom, ∘ a halogen atom, ∘ a hydroxyl group, or ∘ an alkyl group comprising from 1 to 12 carbon atoms; • L 1 and L 2 may be identical or different and represent a saturated or unsaturated, linear or branched hydrocarbon chain comprising from 1 to 22 carbon atoms; • B is an optionally substituted nucleobase, selected from the group consisting of purine nucleobases, pyrimidine nucleobases, and non-natural monocyclic or bicyclic heterocyclic nucleobases wherein each cycle comprises from 4 to 7 atoms. • Oligo represents a nucleic acid sequence of at least 10 nucleotides, said nucleic acid sequence including a series of at least 4 consecutive guanine residues located in the middle of said sequence, i.e. wherein the series of guanine residues is not located at the 5' end or at the 3' end of the nucleic acid sequence, and is separated from each end of the nucleic acid sequence by a number of nucleotides corresponding to at least 25% of the total number of nucleotides of the nucleic acid sequence, the number of nucleotides separating the series of guanine from the 5' end and the 3' end of the nucleic acid sequence being identical or different, wherein said nucleic acid sequence may be oriented 3'-5' or 5'-3' and/or may comprise modified nucleotides; • Y represents a divalent linker moiety selected from ether -O-, thio - S-, amino -NH-, and methylene -CH 2 -; • R 3 and R 4 may be identical or different and represent: ∘ a hydrogen atom, ∘ a halogen atom, ∘ a hydroxyl group, or ∘ an alkyl group comprising from 1 to 12 carbon atoms; ∘ a hydrogen atom, ∘ a halogen atom, ∘ a hydroxyl group, or ∘ an alkyl group comprising from 1 to 12 carbon atoms; • L 1 and L 2 may be identical or different and represent a saturated or unsaturated, linear or branched hydrocarbon chain comprising from 1 to 22 carbon atoms; • B is an optionally substituted nucleobase, selected from the group consisting of purine nucleobases, pyrimidine nucleobases, and non-natural monocyclic or bicyclic heterocyclic nucleobases wherein each cycle comprises from 4 to 7 atoms.
Neratinib or a pharmaceutically acceptable salt thereof for use in a method of treating a HER-2-positive solid tumor, wherein the method further comprises administering capecitabine.
A process for producing petrochemicals from crude oil, the process comprising: passing the crude oil and hydrogen into a hydroprocessing reactor, the hydroprocessing reactor comprising one or more hydroprocessing catalysts that produce a hydrotreated oil; separating the hydrotreated oil into a lesser boiling point fraction and a greater boiling point fraction, where the greater boiling point fraction is a hydrocarbon containing stream having a boiling point of at least 500°C, and the lesser boiling point fraction is a hydrocarbon containing stream having a boiling point of less than 500°C; passing the lesser boiling point fraction to a pyrolysis section of a steam cracker to produce a pyrolysis effluent comprising olefins, aromatics, or both; passing the greater boiling point fraction to a gasifier, where the gasifier produces hydrogen; and passing at least a portion of the hydrogen produced by the gasifier to the hydroprocessing reactor. passing the crude oil and hydrogen into a hydroprocessing reactor, the hydroprocessing reactor comprising one or more hydroprocessing catalysts that produce a hydrotreated oil; separating the hydrotreated oil into a lesser boiling point fraction and a greater boiling point fraction, where the greater boiling point fraction is a hydrocarbon containing stream having a boiling point of at least 500°C, and the lesser boiling point fraction is a hydrocarbon containing stream having a boiling point of less than 500°C; passing the lesser boiling point fraction to a pyrolysis section of a steam cracker to produce a pyrolysis effluent comprising olefins, aromatics, or both; passing the greater boiling point fraction to a gasifier, where the gasifier produces hydrogen; and passing at least a portion of the hydrogen produced by the gasifier to the hydroprocessing reactor.
An electromechanical micromachined transducer having a cellular structure, comprising: - a free movable membrane consisting of a thin peripheral part and a thick central part, - an insulating layer supporting the membrane, - a first wafer being an incised substrate bound to the membrane by the insulating layer, - a second wafer bound to the substrate, wherein the cellular structure is arranged such that it presents: - vertical gaps each having a gap distance between the side walls of the thick central part of the membrane and vertical side walls of the incised substrate, - a first horizontal gap having a first gap distance between the membrane thin peripheral part and the incised substrate, and - a second horizontal gap having a second gap distance between the bottom part of the thick central part and the second wafer, characterized in that the first gap distance and the second gap distance of the first and second horizontal gaps (106, 107), respectively, are larger than the gap distance of the vertical gaps, - wherein the membrane and the substrate are conductive, and - wherein the side walls of the thick central part of the membrane and vertical side walls of the incised substrate are configured for application of an actuation voltage. - a free movable membrane consisting of a thin peripheral part and a thick central part, - an insulating layer supporting the membrane, - a first wafer being an incised substrate bound to the membrane by the insulating layer, - a second wafer bound to the substrate, wherein the cellular structure is arranged such that it presents: - vertical gaps each having a gap distance between the side walls of the thick central part of the membrane and vertical side walls of the incised substrate, - a first horizontal gap having a first gap distance between the membrane thin peripheral part and the incised substrate, and - a second horizontal gap having a second gap distance between the bottom part of the thick central part and the second wafer, characterized in that the first gap distance and the second gap distance of the first and second horizontal gaps (106, 107), respectively, are larger than the gap distance of the vertical gaps, - wherein the membrane and the substrate are conductive, and - wherein the side walls of the thick central part of the membrane and vertical side walls of the incised substrate are configured for application of an actuation voltage.
A lightning strike protection means for applying automatically to a fibre composite component, having: - a metal strip, and - a bendable reinforcement structure for stabilising the metallic strip during a laying process,wherein the reinforcement structure is attached to the metal strip over the entire length of the metal strip, wherein the reinforcement structure has a width that is less than the width of the metal strip characterized in that the reinforcement structure consists of fiber groups (6b, 6c) of unidirectional fibers extending in the longitudinal direction (x) of the metal strip, wherein the fiber groups (6b, 6c) are positioned in opposite border areas of the metal strip. - a metal strip, and - a bendable reinforcement structure for stabilising the metallic strip during a laying process,wherein the reinforcement structure is attached to the metal strip over the entire length of the metal strip, wherein
A surgical limb positioning apparatus comprising: an elongated, hollow boom member having a proximal end, a distal end and a longitudinal axis extending therebetween; a carriage disposed within the boom member and moveable along the longitudinal axis; a first flexible member attached to a first side of the carriage and exiting the boom member at a first aperture located at the proximal end of the boom member; a second flexible member attached to a second side of the carriage such that the flexible member cannot rotate relative to the longitudinal axis of the boom member, the second flexible member exiting the boom member at a second aperture located at the distal end of the boom member; a connector assembly attached to a free end of the second flexible member; and a drape assembly; characterized in that: a free end of the first flexible member is configured for attachment to a weight; the connector assembly is for forming a sterile connection to a drape assembly, and wherein one of the connector assembly and the drape assembly comprises an anti-rotation mechanism configured to maintain an operative limb of a patient in a pre-selected position. an elongated, hollow boom member having a proximal end, a distal end and a longitudinal axis extending therebetween; a carriage disposed within the boom member and moveable along the longitudinal axis; a first flexible member attached to a first side of the carriage and exiting the boom member at a first aperture located at the proximal end of the boom member; a second flexible member attached to a second side of the carriage such that the flexible member cannot rotate relative to the longitudinal axis of the boom member, the second flexible member exiting the boom member at a second aperture located at the distal end of the boom member; a connector assembly attached to a free end of the second flexible member; and a drape assembly; characterized in that: a free end of the first flexible member is configured for attachment to a weight; the connector assembly is for forming a sterile connection to a drape assembly, and wherein one of the connector assembly and the drape assembly comprises an anti-rotation mechanism configured to maintain an operative limb of a patient in a pre-selected position. a free end of the first flexible member is configured for attachment to a weight; the connector assembly is for forming a sterile connection to a drape assembly, and wherein one of the connector assembly and the drape assembly comprises an anti-rotation mechanism configured to maintain an operative limb of a patient in a pre-selected position.
A method for processing requests in a bus architecture comprising at least two master devices (301a, 301b) connected to at least one slave device via a bus, the architecture comprising an optimiser for the or each slave device, each optimiser for buffering incoming requests for the respective slave device, the method comprising the steps of: a) a first of the at least two master devices (301a or 301b) sending a write request for a slave device to the bus; b) generating a fence indicator associated with the write request, the fence indicator indicating that the write request to the slave device should be completed before subsequently issued requests from at least the first of the master devices to any slave device are commenced; c) adding the fence indicator to the write request, and sending the write request including the fence indicator to the or each optimiser; d) the or each optimiser processing all its requests issued before the write request with which the fence indicator is associated, and the optimiser of the slave device to which the write request was directed further processing the write request itself, and the or each optimiser deferring the processing of any requests from at least the first master device issued after the write request with which the fence indicator is associated; e) the or each optimiser outputting, once all its requests issued before the write request with which the fence indicator is associated have been processed, and if the optimiser is the optimiser of the slave device to which the write request was directed, once all its requests issued before the write request with which the fence indicator is associated, and the write request itself, have been processed, a completion indicator. a) a first of the at least two master devices (301a or 301b) sending a write request for a slave device to the bus; b) generating a fence indicator associated with the write request, the fence indicator indicating that the write request to the slave device should be completed before subsequently issued requests from at least the first of the master devices to any slave device are commenced; c) adding the fence indicator to the write request, and sending the write request including the fence indicator to the or each optimiser; d) the or each optimiser processing all its requests issued before the write request with which the fence indicator is associated, and the optimiser of the slave device to which the write request was directed further processing the write request itself, and the or each optimiser deferring the processing of any requests from at least the first master device issued after the write request with which the fence indicator is associated; e) the or each optimiser outputting, once all its requests issued before the write request with which the fence indicator is associated have been processed, and if the optimiser is the optimiser of the slave device to which the write request was directed, once all its requests issued before the write request with which the fence indicator is associated, and the write request itself, have been processed, a completion indicator.
A vane for an aircraft turbomachine, this vane comprising a blade and a cooling circuit inside the blade, this cooling circuit comprising at least one longitudinal cavity for the flow of a cooling air stream, the cooling circuit further comprising projecting elements into said cavity and which are configured to disrupt said air stream, characterised in that each of said projecting elements has the general shape of an arch and comprises two lateral legs and a median roof, the legs extending between a first wall of the cavity and said roof, this roof interconnecting said legs, and in that each of said elements defines internally, with said first wall, a first passage cross-section (S1-S1'), and externally, with a second wall opposite the first wall, a second passage cross-section (S2-S2'), and each of said elements being configured so that said first or second passage cross-section is reduced from upstream to downstream with respect to the direction of said air stream.
A paste composition containing: copper fine particles having a thickness or minor axis of 10 to 500 nm, calculated as an average value of 10 copper fine particles randomly selected based on an observation image of a SEM, the average value being an arithmetic mean value, and coated with amino alcohol represented by the following chemical formula, wherein an amine compound including at least one selected from alkylamines and alkoxyamines adheres to a surface of the copper fine particles; and an organic solvent, wherein a compounding amount of the organic solvent is 2 to 20 parts by mass relative to 100 parts by mass of the copper fine particles, where R 1 s may be identical or different, each independently represent a hydrogen atom, an alkyl group with a carbon number of 1 to 4, a hydroxy group, or a methoxy group, n and m each represent an integer of 0 to 10, and m + n is 10 or less. copper fine particles having a thickness or minor axis of 10 to 500 nm, calculated as an average value of 10 copper fine particles randomly selected based on an observation image of a SEM, the average value being an arithmetic mean value, and coated with amino alcohol represented by the following chemical formula, wherein an amine compound including at least one selected from alkylamines and alkoxyamines adheres to a surface of the copper fine particles; and an organic solvent, wherein a compounding amount of the organic solvent is 2 to 20 parts by mass relative to 100 parts by mass of the copper fine particles, where R 1 s may be identical or different, each independently represent a hydrogen atom, an alkyl group with a carbon number of 1 to 4, a hydroxy group, or a methoxy group, n and m each represent an integer of 0 to 10, and m + n is 10 or less.
An electrode for medical applications for neuromodulation and/or nerve stimulation and/or neurological signal detection which can be compressed and expanded for insertion into a hollow organ in a body and which is connected or can be connected to a power supply and a compressible and expandable lattice structure made up of lattice webs which form cells, wherein the lattice structure is connected or can be connected to the power supply and forms at least one electrically conductive region and at least one electrically insulated region, characterized in that the lattice structure comprises a bearing layer, at least one insulating layer and at least one electrically conductive layer.
An aircraft undercarriage including electrical equipment (2, 3) fastened to a portion of the undercarriage and a lightning protection device comprising at least one shield fastened to said portion of the undercarriage by fastener means so as to extend in register with the electrical equipment (2, 3) in a position that is spaced apart therefrom, the shield comprising at least a first plate made of electrically conductive material that is arranged to absorb a major portion of the heat energy that is generated by the passage of a lightning wave and to discharge the electric charge of the lightning wave.
A pest control composition containing a combination of -1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine and an ester compound which is 2,3,5,6-tetrafluoro-4-methoxymethylbenzyl -3- (1-propenyl)-2,2-dimethylcyclopropanecarboxylate, wherein the weight ratio of -1-(2-chloro-l,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine to the ester compound is within the range of from 19: 1 to 1: 2.
Guiding apparatus for connecting a fluid cartridge, in particular a CO 2 pressurised gas bottle, in particular for sanitary applications, comprising an upper region for securing the guiding device to a connection of a fluid line, and a lower region for introducing the fluid cartridge into the guiding apparatus in an introduction direction which at least partially surrounds the fluid cartridge, characterised in that in at least one of the two regions (2, 3), in particular at least in the lower region, at least one radially inwardly extending guiding element is arranged. a lower region for introducing the fluid cartridge into the guiding apparatus in an introduction direction which at least partially surrounds the fluid cartridge, characterised in that in at least one of the two regions (2, 3), in particular at least in the lower region, at least one radially inwardly extending guiding element is arranged.