A cassette (21; 61; 101) for loading a nutritional feeding set onto a peristaltic infusion pump, the cassette (21; 61; 101) comprising: a) a pump tubing segment (31; 71; 111) for engagement with a motor-driven pumping mechanism (22; 122) located within a receiving portion of a peristaltic infusion pump, the pump tubing segment (31; 71; 111) including: i) an anti-flow mechanism in the form of a pre-set kink for preventing free flow of fluid through the pump tubing segment (31; 71; 111), wherein the pre-set kink causes an obstruction to flow when the pump tubing segment (31; 71; 111) is not engaged with the pumping mechanism (22; 122), and wherein the obstruction is relieved when the pump tubing segment (31; 71; 111) is engaged with the pumping mechanism (22; 122); and ii) a pair of free ends; and b) a connector (30; 70) for connecting to the receiving portion of the infusion pump, the connector (30; 70) including: i) a first mating member (54, 55) for reversibly connecting to a second mating member located in the receiving portion of the infusion pump, wherein connection of the first mating member (54, 55) with the second mating member aligns the pump tubing segment (31; 71; 111) with the pumping mechanism (22; 122) and locks the cassette (21; 61; 101) in place within the receiving portion; ii) a first set of attachment structures (35, 36, 37, 38; 85, 86, 87, 88) for connecting inflow tubing and outflow tubing of a nutritional feeding set to the connector (30; 70); and iii) a second set of attachment structures (35, 36, 37, 38; 85, 86, 87, 88) for connecting the free ends of the pump tubing segment (31; 71; 111) to the connector (30; 70), wherein the attachment structures are hollow and fluidly connect the inflow tubing and the outflow tubing to the pump tubing segment (31; 71; 111). a) a pump tubing segment (31; 71; 111) for engagement with a motor-driven pumping mechanism (22; 122) located within a receiving portion of a peristaltic infusion pump, the pump tubing segment (31; 71; 111) including: i) an anti-flow mechanism in the form of a pre-set kink for preventing free flow of fluid through the pump tubing segment (31; 71; 111), wherein the pre-set kink causes an obstruction to flow when the pump tubing segment (31; 71; 111) is not engaged with the pumping mechanism (22; 122), and wherein the obstruction is relieved when the pump tubing segment (31; 71; 111) is engaged with the pumping mechanism (22; 122); and ii) a pair of free ends; and i) an anti-flow mechanism in the form of a pre-set kink for preventing free flow of fluid through the pump tubing segment (31; 71; 111), wherein the pre-set kink causes an obstruction to flow when the pump tubing segment (31; 71; 111) is not engaged with the pumping mechanism (22; 122), and wherein the obstruction is relieved when the pump tubing segment (31; 71; 111) is engaged with the pumping mechanism (22; 122); and ii) a pair of free ends; and b) a connector (30; 70) for connecting to the receiving portion of the infusion pump, the connector (30; 70) including: i) a first mating member (54, 55) for reversibly connecting to a second mating member located in the receiving portion of the infusion pump, wherein connection of the first mating member (54, 55) with the second mating member aligns the pump tubing segment (31; 71; 111) with the pumping mechanism (22; 122) and locks the cassette (21; 61; 101) in place within the receiving portion; ii) a first set of attachment structures (35, 36, 37, 38; 85, 86, 87, 88) for connecting inflow tubing and outflow tubing of a nutritional feeding set to the connector (30; 70); and iii) a second set of attachment structures (35, 36, 37, 38; 85, 86, 87, 88) for connecting the free ends of the pump tubing segment (31; 71; 111) to the connector (30; 70), wherein the attachment structures are hollow and fluidly connect the inflow tubing and the outflow tubing to the pump tubing segment (31; 71; 111). i) a first mating member (54, 55) for reversibly connecting to a second mating member located in the receiving portion of the infusion pump, wherein connection of the first mating member (54, 55) with the second mating member aligns the pump tubing segment (31; 71; 111) with the pumping mechanism (22; 122) and locks the cassette (21; 61; 101) in place within the receiving portion; ii) a first set of attachment structures (35, 36, 37, 38; 85, 86, 87, 88) for connecting inflow tubing and outflow tubing of a nutritional feeding set to the connector (30; 70); and iii) a second set of attachment structures (35, 36, 37, 38; 85, 86, 87, 88) for connecting the free ends of the pump tubing segment (31; 71; 111) to the connector (30; 70), wherein the attachment structures are hollow and fluidly connect the inflow tubing and the outflow tubing to the pump tubing segment (31; 71; 111).