An integrated circuit comprising: an integrated-circuit-system-power-manager; and an interconnect network (118, 218, 318, 418) partitioned into multiple power domains, the interconnect network comprising: an interconnect-power-manager (106, 306, 406, 506, 606) comprising: signalling ports configured to communicate with different agents within the interconnect network (118, 218, 318, 418); and hardware circuitry configured to cooperate with the integrated-circuit-system-power-manager, wherein the hardware circuitry is integrated into the interconnect network (118, 218, 318, 418) to manage a quiescent state for all components in each power domain in the interconnect network (118, 218, 318, 418); the integrated circuit further comprising: one or more initiator cores coupled to their own corresponding initiator agent; and one or more target cores coupled to their own corresponding target agent, wherein each agent has their own power state managed by the integrated-circuit-system-power-manager, which is separate from the interconnect-power-manager (106, 306, 406, 506, 606) managing the multiple power domains of the interconnected network (118, 218, 318, 418); the interconnect network further comprising: a routing pathway that spans across one or more power domain boundaries, wherein the routing pathway causes interdependencies of power domains within the interconnect network (118, 218, 318, 418) other than the locations of the power domains containing an initiator agent generating a new transaction and a final target agent of the new transaction; wherein the integrated-circuit-system-power-manager is configured to cooperate and communicate with the interconnect-power-manager (106, 306, 406, 506, 606) 1) to quiesce, 2) to wake up, or 3) any combination of the two, one or more of the multiple power domains within the interconnect network (118, 218, 318, 418), where each power domain is separately controllable from other power domains in the interconnect network (118, 218, 318, 418) by the interconnect-power-manager (106, 306, 406, 506, 606). an integrated-circuit-system-power-manager; and an interconnect network (118, 218, 318, 418) partitioned into multiple power domains, the interconnect network comprising: an interconnect-power-manager (106, 306, 406, 506, 606) comprising: signalling ports configured to communicate with different agents within the interconnect network (118, 218, 318, 418); and hardware circuitry configured to cooperate with the integrated-circuit-system-power-manager, wherein the hardware circuitry is integrated into the interconnect network (118, 218, 318, 418) to manage a quiescent state for all components in each power domain in the interconnect network (118, 218, 318, 418); an interconnect-power-manager (106, 306, 406, 506, 606) comprising: signalling ports configured to communicate with different agents within the interconnect network (118, 218, 318, 418); and hardware circuitry configured to cooperate with the integrated-circuit-system-power-manager, wherein the hardware circuitry is integrated into the interconnect network (118, 218, 318, 418) to manage a quiescent state for all components in each power domain in the interconnect network (118, 218, 318, 418); signalling ports configured to communicate with different agents within the interconnect network (118, 218, 318, 418); and hardware circuitry configured to cooperate with the integrated-circuit-system-power-manager, wherein the hardware circuitry is integrated into the interconnect network (118, 218, 318, 418) to manage a quiescent state for all components in each power domain in the interconnect network (118, 218, 318, 418); one or more initiator cores coupled to their own corresponding initiator agent; and one or more target cores coupled to their own corresponding target agent, wherein each agent has their own power state managed by the integrated-circuit-system-power-manager, which is separate from the interconnect-power-manager (106, 306, 406, 506, 606) managing the multiple power domains of the interconnected network (118, 218, 318, 418); the interconnect network further comprising: a routing pathway that spans across one or more power domain boundaries, wherein the routing pathway causes interdependencies of power domains within the interconnect network (118, 218, 318, 418) other than the locations of the power domains containing an initiator agent generating a new transaction and a final target agent of the new transaction; a routing pathway that spans across one or more power domain boundaries, wherein the routing pathway causes interdependencies of power domains within the interconnect network (118, 218, 318, 418) other than the locations of the power domains containing an initiator agent generating a new transaction and a final target agent of the new transaction; wherein the integrated-circuit-system-power-manager is configured to cooperate and communicate with the interconnect-power-manager (106, 306, 406, 506, 606) 1) to quiesce, 2) to wake up, or 3) any combination of the two, one or more of the multiple power domains within the interconnect network (118, 218, 318, 418), where each power domain is separately controllable from other power domains in the interconnect network (118, 218, 318, 418) by the interconnect-power-manager (106, 306, 406, 506, 606).