Locking device for a door that is to be mounted on a frame, said door having an inside face and an outside face and said frame having an inside face and an outside face, the locking device comprising: - an outside door handle which is to be arranged on the outside face of the door, and an inside door handle which is to be arranged on the inside face of the door, and - a first bolt which is to be carried by the door and is movable between a protruding position and a retracted position, - a first removable strike box which is to be carried by the frame opposite the first bolt and comprises a movable part which is capable of tilting about a tilting axis, independently of the position of the first bolt, - a latch which is to be carried by the frame and is movable between a first position, in which the latch cooperates with the movable part in order to keep it immobilised so that it forms a stop for the first bolt in the protruding position, and a second position, in which the latch is held away from the movable part in order to allow it to tilt freely about the tilting axis, - mechanical means for actuating the latch, which means are to be accessible from the outside face of the frame and are capable of displacing the latch between its first position and its second position, and first displacement means for displacing the first bolt between its protruding position and its retracted position, characterised in that: - the first displacement means for displacing the first bolt are activatable only by the inside door handle from among the inside door handle and the outside door handle, and in that the locking device comprises: - a second bolt which is to be carried by the door and is movable between a protruding position and a retracted position, - second displacement means for displacing the second bolt between its protruding position and its retracted position, the second displacement means being activatable by each door handle from among the inside door handle and the outside door handle. - an outside door handle which is to be arranged on the outside face of the door, and an inside door handle which is to be arranged on the inside face of the door, and - a first bolt which is to be carried by the door and is movable between a protruding position and a retracted position, - a first removable strike box which is to be carried by the frame opposite the first bolt and comprises a movable part which is capable of tilting about a tilting axis, independently of the position of the first bolt, - a latch which is to be carried by the frame and is movable between a first position, in which the latch cooperates with the movable part in order to keep it immobilised so that it forms a stop for the first bolt in the protruding position, and a second position, in which the latch is held away from the movable part in order to allow it to tilt freely about the tilting axis, - mechanical means for actuating the latch, which means are to be accessible from the outside face of the frame and are capable of displacing the latch between its first position and its second position, and - the first displacement means for displacing the first bolt are activatable only by the inside door handle from among the inside door handle and the outside door handle, - a second bolt which is to be carried by the door and is movable between a protruding position and a retracted position, - second displacement means for displacing the second bolt between its protruding position and its retracted position, the second displacement means being activatable by each door handle from among the inside door handle and the outside door handle.