Motorcycle suspension comprising - a portion of frame of an associable motorcycle, - a fork hinged to said portion of frame of the motorcycle in relation to at least one hinge pin, - a damper unit, positioned between the frame and the fork, comprising at least one spring and at least one damper so as to permit a relative rotation of the fork in relation to the frame around said at least one hinge pin, wherein - the suspension comprises a load sensor to measure the load weighing on the damper unit depending on the shift of the fork in relation to the frame, - and a control unit operatively connected to said load sensor, - wherein the suspension comprises regulation means of the damper unit, comprising regulation means of the pre-loading of the spring and regulation means of the damping of the damper, in which the pre-loading regulation means are suitable for modifying the pre-loading applied to the spring and the damper regulation means modify the damping capacity of the oscillations induced by the spring, in a static condition of the vehicle, - wherein the control unit is operatively connected to the regulation means of the damper unit so as to vary the setting of the regulation means depending on the load signal received from the load sensor, so as to adapt the pre-loading of the spring and the damping of the damper to the load effectively weighing on the damper unit characterized by - the target pre-loading values of the spring and damping values of the damper are stored in the control unit depending on the load effectively weighing on the damper unit, and wherein the control unit is configured to: cyclically perform verification of the functioning condition of the vehicle and after having identified whether it is in said static condition or moving condition, verifies that the effective pre-loading and damping parameters are the same as those stored in the control unit; and in the case of discrepancy between such values the control unit performs the regulations required. - a portion of frame of an associable motorcycle, - a fork hinged to said portion of frame of the motorcycle in relation to at least one hinge pin, - a damper unit, positioned between the frame and the fork, comprising at least one spring and at least one damper so as to permit a relative rotation of the fork in relation to the frame around said at least one hinge pin, - the suspension comprises a load sensor to measure the load weighing on the damper unit depending on the shift of the fork in relation to the frame, - and a control unit operatively connected to said load sensor, - wherein the suspension comprises regulation means of the damper unit, comprising regulation means of the pre-loading of the spring and regulation means of the damping of the damper, in which the pre-loading regulation means are suitable for modifying the pre-loading applied to the spring and the damper regulation means modify the damping capacity of the oscillations induced by the spring, in a static condition of the vehicle, - wherein the control unit is operatively connected to the regulation means of the damper unit so as to vary the setting of the regulation means depending on the load signal received from the load sensor, so as to adapt the pre-loading of the spring and the damping of the damper to the load effectively weighing on the damper unit characterized by - the target pre-loading values of the spring and damping values of the damper are stored in the control unit depending on the load effectively weighing on the damper unit,