mhurhangee/ep-ind-claims huggingface dataset:
Vehicle seat arrangement for a motor vehicle, with - a backrest, - a seat cushion, - at least one airbag module, the airbag module being arranged in the backrest and the airbag module comprising at least one airbag, - a tether mechanism for the airbag module, the tether mechanism comprising at least one tether arrangement, the tether arrangement being connected to the airbag and with at least one end to the backrest and/or seat cushion, and - a seat belt arrangement, the seat belt arrangement comprising a seat belt, wherein in a fastened state a section of the seat belt extends diagonally from an upper location on a first side of the backrest towards a lower location on a second side of the backrest, the second side being opposite to the first side, wherein an airbag of the at least one airbag module is shaped in such a way that in the deployed state a frontal section of the airbag is arranged directly in front of a central axis of the backrest, wherein the at least one airbag module is arranged on the second side, characterized in that the first side is the inboard side of the motor vehicle and the second side is the outboard side of the vehicle. - a backrest, - a seat cushion, - at least one airbag module, the airbag module being arranged in the backrest and the airbag module comprising at least one airbag, - a tether mechanism for the airbag module, the tether mechanism comprising at least one tether arrangement, the tether arrangement being connected to the airbag and with at least one end to the backrest and/or seat cushion, and - a seat belt arrangement, the seat belt arrangement comprising a seat belt, wherein in a fastened state a section of the seat belt extends diagonally from an upper location on a first side of the backrest towards a lower location on a second side of the backrest, the second side being opposite to the first side, wherein an airbag of the at least one airbag module is shaped in such a way that in the deployed state a frontal section of the airbag is arranged directly in front of a central axis of the backrest, wherein the at least one airbag module is arranged on the second side, characterized in that the first side is the inboard side of the motor vehicle and the second side is the outboard side of the vehicle.
An orthopaedic feedback system having at least one orthopaedic support apparatus in the form of an orthosis or prosthesis, which has at least one support element in engagement with a first body part (1, 3) or a first body region, a compressive force detection device, which has multiple compressive force detection sensors and is configured to detect a compressive force acting on the first body part (1, 3), the first body region or the at least one support element, and a reproduction device, which has a communications link with the compressive force detection device and has at least one reproduction element, which is in contact with a second body part or a second body region or is in engagement with the second body part or the second body region and is configured for the tactile reproduction, on the second body part or the second body region, of compressive force signals detected using the compressive force detection device, characterised in that the reproduction element has a reproduction matrix, which has multiple spaced-apart actuators and is configured to reproduce, on the second body part or the second body region, a compressive force profile detected by the compressive force detection device. at least one orthopaedic support apparatus in the form of an orthosis or prosthesis, which has at least one support element in engagement with a first body part (1, 3) or a first body region, a compressive force detection device, which has multiple compressive force detection sensors and is configured to detect a compressive force acting on the first body part (1, 3), the first body region or the at least one support element, and a reproduction device, which has a communications link with the compressive force detection device and has at least one reproduction element, which is in contact with a second body part or a second body region or is in engagement with the second body part or the second body region and is configured for the tactile reproduction, on the second body part or the second body region, of compressive force signals detected using the compressive force detection device, characterised in that the reproduction element has a reproduction matrix, which has multiple spaced-apart actuators and is configured to reproduce, on the second body part or the second body region, a compressive force profile detected by the compressive force detection device.
An engineered Fok I cleavage half-domain, wherein the engineered cleavage half-domain comprises one or more mutations as follows: (a) the wild-type residue at position 479 is replaced with a Gln or Thr residue (I479Q or I479T); (b) the wild-type residue at position 418 is replaced with a Glu or Asp residue (S418E or S418D); (c) the wild-type residue at position 446 is replaced with an Asp residue (S446D); (d) the wild-type residue at position 448 is replaced with an Ala residue (K448A); (e) the wild type residue at position 481 is replaced with an Ala, Glu, Cys, or Ser residue (Q481A, Q481E, Q481C or Q481S); (f) the wild-residue at position 416 is replaced with a Glu, Asp, His or Asn residue (R416E, R416D, R416H or R416N); (g) the wild-type residue at position 422 is replaced with a His residue (R422H); (h) the wild-type residue at position 424 is replaced with a Phe residue (L424F); (i) the wild-type residue at position 472 is replaced with an Asp residue (S472D); (j) the wild-type residue at position 476 is replaced with a Glu residue or a Gly residue (N476E or N476G); (k) the wild-type residue at position 478 is replaced with an Asp residue (P478D); (l) the wild-type residue at position 480 is replaced with an Asp residue (G480D); (m) the wild-type residue at position 525 is replaced with an Ala, Cys, Glu, Ile, Ser, Thr or Val residue (K525A, K525C, K525E, K525I, K525S, K525T or K525V); and/or (n) the wild-type residue at position 542 is replaced with an Asp residue (N542D), wherein the amino acid residues are numbered relative to full length Fok I wild-type cleavage domain, as shown in SEQ ID NO:1. (a) the wild-type residue at position 479 is replaced with a Gln or Thr residue (I479Q or I479T); (b) the wild-type residue at position 418 is replaced with a Glu or Asp residue (S418E or S418D); (c) the wild-type residue at position 446 is replaced with an Asp residue (S446D); (d) the wild-type residue at position 448 is replaced with an Ala residue (K448A); (e) the wild type residue at position 481 is replaced with an Ala, Glu, Cys, or Ser residue (Q481A, Q481E, Q481C or Q481S); (f) the wild-residue at position 416 is replaced with a Glu, Asp, His or Asn residue (R416E, R416D, R416H or R416N); (g) the wild-type residue at position 422 is replaced with a His residue (R422H); (h) the wild-type residue at position 424 is replaced with a Phe residue (L424F); (i) the wild-type residue at position 472 is replaced with an Asp residue (S472D); (j) the wild-type residue at position 476 is replaced with a Glu residue or a Gly residue (N476E or N476G); (k) the wild-type residue at position 478 is replaced with an Asp residue (P478D); (l) the wild-type residue at position 480 is replaced with an Asp residue (G480D); (m) the wild-type residue at position 525 is replaced with an Ala, Cys, Glu, Ile, Ser, Thr or Val residue (K525A, K525C, K525E, K525I, K525S, K525T or K525V); and/or (n) the wild-type residue at position 542 is replaced with an Asp residue (N542D), wherein the amino acid residues are numbered relative to full length Fok I wild-type cleavage domain, as shown in SEQ ID NO:1.
A filling device for multi-head dosing machines designed for the weighing and dosing of food products, or the like, to be packaged, having a substantially carousel-shaped form extending vertically and comprising a multitude of dosing heads characterised in that the dosing heads are positioned in a circular fashion outside a rotatable plate on which are positioned the portions, above which is positioned a frame which is also of the carousel type with a diameter less than the plate, comprising a plurality of mechanical linkages connected by a kinematic mechanism to a respective plurality of movable blades, each of which is positioned at a respective dosing head, allowing the blades to move angularly and push the product to said respective dosing head.
A polypeptide comprising a variant amino acid sequence of SEQ ID NO: 1, wherein the polypeptide has alpha-amylase activity and exhibits an improved wash performance compared to the parent polypeptide of SEQ ID NO: 1, said variant amino acid sequence comprises the following substitutions in SEQ ID NO: 1 using the numbering of the amino acid sequence of SEQ ID NO: 2: L202M and T246(I/L/V), and has at least 80% sequence identity to SEQ ID NOs: 1 or 2.
A radio resource control RRC connection releasing method, comprising: receiving, by a terminal, a deactivation indication message sent by a first base station, wherein the deactivation indication message carries indication information related to mobility control of the terminal, and the first base station is a serving base station of the terminal; and releasing, by the terminal, an RRC connection according to the deactivation indication message, reserving context information of the terminal, and entering an inactive state, wherein the indication information is used to indicate a cell or base station that is preferred when the terminal in the inactive state performs cell reselection. receiving, by a terminal, a deactivation indication message sent by a first base station, wherein the deactivation indication message carries indication information related to mobility control of the terminal, and the first base station is a serving base station of the terminal; and releasing, by the terminal, an RRC connection according to the deactivation indication message, reserving context information of the terminal, and entering an inactive state, wherein the indication information is used to indicate a cell or base station that is preferred when the terminal in the inactive state performs cell reselection.
Measuring system for determining a dispensed amount of hydrogen of a hydrogen dispensing location, in particular a hydrogen fueling station, from a hydrogen dispensing unit in form of a filling point present there to a receiving tank, with a measuring unit, wherein the measuring unit has a flowmeter which can be arranged between the hydrogen dispensing unit in form of the filling point and the receiving tank, wherein the measuring system is designed to establish a fluid-tight connection between the hydrogen dispensing unit in form of the filling point and the receiving tank whereby a fluid-tight connection can be established from the hydrogen-dispensing unit in the form of a filling point to the measuring unit and a fluid-tight connection can be established from the measuring unit to the receiving tank, wherein the measuring unit is designed to lead hydrogen dispensed by the hydrogen dispensing unit in form of the filling point through the flowmeter of the measuring unit to the receiving tank and characterized in that the flowmeter has an active cooling system which is designed to cool the flowmeter before the start of the transfer of the hydrogen in such a way that there is essentially no change in the temperature in the flowmeter during the transfer. with a measuring unit, wherein the measuring unit has a flowmeter which can be arranged between the hydrogen dispensing unit in form of the filling point and the receiving tank, wherein the measuring system is designed to establish a fluid-tight connection between the hydrogen dispensing unit in form of the filling point and the receiving tank whereby a fluid-tight connection can be established from the hydrogen-dispensing unit in the form of a filling point to the measuring unit and a fluid-tight connection can be established from the measuring unit to the receiving tank, wherein the measuring unit is designed to lead hydrogen dispensed by the hydrogen dispensing unit in form of the filling point through the flowmeter of the measuring unit to the receiving tank and characterized in that the flowmeter has an active cooling system which is designed to cool the flowmeter before the start of the transfer of the hydrogen in such a way that there is essentially no change in the temperature in the flowmeter during the transfer.
Method for testing an overspeed protection apparatus of a single-shaft system having a gas turbine and a steam turbine, having the steps of: b) operating the single-shaft system such that no steam is introduced into the steam turbine and the gas turbine drives the steam turbine; c) raising the mass flow of the fuel fed into the gas turbine such that the speed of the single-shaft system reaches a steam turbine limit speed, wherein the overspeed protection apparatus is set up such that a first overspeed protection is triggered as soon as the speed of the single-shaft system reaches the steam turbine limit speed; d) checking whether the first overspeed protection is triggered. b) operating the single-shaft system such that no steam is introduced into the steam turbine and the gas turbine drives the steam turbine; c) raising the mass flow of the fuel fed into the gas turbine such that the speed of the single-shaft system reaches a steam turbine limit speed, wherein the overspeed protection apparatus is set up such that a first overspeed protection is triggered as soon as the speed of the single-shaft system reaches the steam turbine limit speed; d) checking whether the first overspeed protection is triggered.
A drive force control apparatus for a vehicle, having at least one engaging element (B, C1, C2) and configured to implement drive force control to control distribution of a drive force generated by a drive power source, to left drive wheel and to a right drive wheel by controlling an engaged state of the at least one engaging element in accordance with a demand for control of the drive force, the drive force control apparatus being characterized by comprising: control demand determining means (38, 40) configured to determine a possibility that the demand for control of the drive force is made, based on a predetermined standard, and engagement control means configured to implement preliminary control, the preliminary control being configured to control the engaged state of the at least one engaging element to a stage prior to implementing of the drive force control if the control demand determining means (38, 40) determined that it is possible that the demand for control would be made. control demand determining means (38, 40) configured to determine a possibility that the demand for control of the drive force is made, based on a predetermined standard, and engagement control means configured to implement preliminary control, the preliminary control being configured to control the engaged state of the at least one engaging element to a stage prior to implementing of the drive force control if the control demand determining means (38, 40) determined that it is possible that the demand for control would be made.
A light-conducting device, comprising k>1 first deflection devices (U11, U21, U31) that are parallel to one another and formed such that light beams which are incident onto the deflection device at an incident angle different from 0° and 90° with respect to an optical axis of the deflection device are deflected in a plane defined by the optical axis and the incident direction in such a way that the direction of the deflected light beam also includes the incident angle with the optical axis, so that the incident beam and the emergent beam include twice the incident angle, and that are arranged along a first direction, and k second deflection devices (U12, U22, U32) that are parallel to one another and arranged along a second direction, wherein a third direction is perpendicular to the first and second direction (X, Y), and wherein each of the second deflection devices (U12, U22, U32) is arranged in a same fourth direction with respect to one of the first deflection devices (U11, U21, U31), characterized in that the first deflection devices (U11, U21, U31) comprise optical axes directed in a fifth direction, characterized in that the second direction is perpendicular to the first direction and the second deflection devices (U12, U22, U32) comprise optical axes directed opposite to the fifth direction, wherein the fifth direction is an angle bisector of an angle between the third and the fourth direction, wherein the first and second deflection devices (U11, U21, U31, U12, U22, U32) are surfaces of prisms, and wherein the light-conducting device comprises k rhombic prisms (61, 62, 63), wherein two surfaces of each of the prisms (61, 62, 63) that are parallel to one another form one of the first and the respective associated second deflection device (U11, U21, U31, U12, U22, U32).
A robot cleaner which performs a cleaning operation in a cleaning area, the robot cleaner comprising: a battery; and a processor configured, in response to a capacity of the battery reaching a predetermined value as the robot cleaner performs the cleaning operation, to: control the robot cleaner to charge some of the battery based on at least one of a charging method of the battery and information on the cleaning area, and clean a remaining area using the charged battery. a battery; and a processor configured, in response to a capacity of the battery reaching a predetermined value as the robot cleaner performs the cleaning operation, to: control the robot cleaner to charge some of the battery based on at least one of a charging method of the battery and information on the cleaning area, and clean a remaining area using the charged battery. control the robot cleaner to charge some of the battery based on at least one of a charging method of the battery and information on the cleaning area, and clean a remaining area using the charged battery.
An absorbent article comprising a liquid pervious topsheet, a liquid impervious backsheet, an absorbent core positioned between the liquid pervious topsheet and the liquid impervious backsheet, said absorbent core comprising a bottom core wrap (120, 800), a top core wrap and absorbent material between the bottom core wrap and the top core wrap, and a capillary acceleration sheet between the absorbent core and the liquid pervious topsheet; wherein the absorbent material comprises superabsorbent particles and optionally cellulosic fluff pulp, wherein the absorbent material is arranged such that one or more channels (140, 150, 160, 170, 180) are formed, wherein less absorbent material per surface area is present in the one or more channels compared to an area around the one or more channels, wherein preferably substantially no absorbent material is present in the one or more channels, wherein the capillary acceleration sheet is a through-air-bonded nonwoven having a basis weight between 20 and 30 gsm.
An isolated antigen-binding molecule, which is capable of binding to human V-type immunoglobulin domain-containing suppressor of T-cell Activation (VISTA) and inhibiting VISTA-mediated signalling, wherein the antigen-binding molecule comprises: (i) a heavy chain variable region incorporating the following CDRs: HC-CDR1 having the amino acid sequence of SEQ ID NO:290 HC-CDR2 having the amino acid sequence of SEQ ID NO:291 HC-CDR3 having the amino acid sequence of SEQ ID NO:278; and (ii) a light chain variable region incorporating the following CDRs: LC-CDR1 having the amino acid sequence of SEQ ID NO:41 LC-CDR2 having the amino acid sequence of SEQ ID NO:295 LC-CDR3 having the amino acid sequence of SEQ ID NO:43. (i) a heavy chain variable region incorporating the following CDRs: HC-CDR1 having the amino acid sequence of SEQ ID NO:290 HC-CDR2 having the amino acid sequence of SEQ ID NO:291 HC-CDR3 having the amino acid sequence of SEQ ID NO:278; and HC-CDR1 having the amino acid sequence of SEQ ID NO:290 HC-CDR2 having the amino acid sequence of SEQ ID NO:291 HC-CDR3 having the amino acid sequence of SEQ ID NO:278; and (ii) a light chain variable region incorporating the following CDRs: LC-CDR1 having the amino acid sequence of SEQ ID NO:41 LC-CDR2 having the amino acid sequence of SEQ ID NO:295 LC-CDR3 having the amino acid sequence of SEQ ID NO:43. LC-CDR1 having the amino acid sequence of SEQ ID NO:41 LC-CDR2 having the amino acid sequence of SEQ ID NO:295 LC-CDR3 having the amino acid sequence of SEQ ID NO:43.
A peptide having an amino acid sequence comprising [E/D/N/Q]-[S/T]-[D/E/Q/N]-[V/L] for use in the treatment, optionally wherein the treatment is prophylactic, of the damaging effect of stroke exacerbated by fever in a subject having a fever of at least 38 degrees Celsius on initiating treatment.
A composition comprising a TGFβ3 polypeptide, and dexamethasone or any salts, esters, or hydrides thereof, for use in a method of: (i) treating or preventing thinning or irregularity of a cornea of a subject; or (ii) treating or preventing a refractive error of the eye of a subject, wherein: the TGFβ3 polypeptide comprises the amino acid sequence of SEQ ID NO: 1; or the TGFβ3 polypeptide shares at least 90% sequence identity to the amino acid sequence of SEQ ID NO: 1, or the TGFβ3 polypeptide comprises at least 100 amino acids of the amino acid sequence of SEQ ID NO: 1. the TGFβ3 polypeptide comprises the amino acid sequence of SEQ ID NO: 1; or the TGFβ3 polypeptide shares at least 90% sequence identity to the amino acid sequence of SEQ ID NO: 1, or the TGFβ3 polypeptide comprises at least 100 amino acids of the amino acid sequence of SEQ ID NO: 1.
A spacer for holding substantially rectangular panel-shaped pipette tip carriers, which are stacked one over the other, spaced apart, wherein the spacer comprises a peripheral lateral wall which forms a substantially rectangular frame with two longitudinal sides and two transverse sides in each case, said frame having a horizontal standing surface on a lower edge for supporting on the upper face of a pipette tip carrier, a horizontal support surface on an upper edge for supporting an additional pipette tip carrier on the lower face, pins protruding vertically upwards from the upper edge on corners between adjacent longitudinal and transverse sides, and bending elements, which can be bent in a direction running at an acute angle to the adjacent longitudinal and transverse sides, on the lateral wall.
A method of preparing kilogram quantities of a compound of formula or a C-7 disodium phosphate ester thereof, wherein R 1 is an optionally substituted C 1 -C 4 alkyl, optionally substituted C 2 -C 4 alkenyl or optionally substituted C 2 -C 5 alkynyl; said method comprising the steps of: a) coupling a compound of formula with an alkyne of formula in the presence of a palladium catalyst wherein Hal is I or Br, and P is a hydroxy protecting group; b) reacting in situ the resultant coupled product of step a) with a compound of formula wherein R 2 is Br, I or CF 3 SO 3, in the presence of CO at a temperature of 25° - 35°C; and c) removing the C-7 hydroxy protecting group to obtain a compound of formula and optionally converting the C-7 hydroxy group into the disodium phosphate ester thereof. a) coupling a compound of formula with an alkyne of formula in the presence of a palladium catalyst wherein Hal is I or Br, and P is a hydroxy protecting group; b) reacting in situ the resultant coupled product of step a) with a compound of formula wherein R 2 is Br, I or CF 3 SO 3, in the presence of CO at a temperature of 25° - 35°C; and c) removing the C-7 hydroxy protecting group to obtain a compound of formula and optionally converting the C-7 hydroxy group into the disodium phosphate ester thereof.