A pneumatic tire comprising an inner liner disposed on the tire inside relative to a carcass ply bridged between a pair of bead portions, wherein said inner liner is composed of a polymer layer stack including a first layer containing a styrene-isobutylene-styrene triblock copolymer, and a second layer containing at least one of a styrene-isoprene-styrene triblock copolymer and a styrene-isobutylene diblock copolymer, wherein i) at least one of said first layer and said second layer is a polymer composition further containing a C4 polymer obtained by polymerizing a monomer unit having 4 carbon atoms by more than or equal to 0.5 mass % and less than or equal to 40 mass %, or ii) said first layer further contains a layered clay mineral with an organic compound intercalated therein by 0.1 part by mass to 50 parts by mass relative to 100 parts by mass of the polymer component, or iii) said first layer further contains at least one kind of rubber component selected from the group consisting of a natural rubber, an isoprene rubber and a butyl rubber by more than or equal to 60 mass % and less than or equal to 95 mass % and said second layer further contains at least one kind of rubber component selected from the group consisting of a natural rubber, an isoprene rubber and a butyl rubber by more than or equal to 15 mass % and less than or equal to 90 mass %, said second layer is arranged to come into contact with a rubber layer of the carcass ply, and said inner liner has a thickness Ge at a shoulder position Pe exceeding 100% and being less than or equal to 500% of a thickness Gc at a crown central position Pc. a first layer containing a styrene-isobutylene-styrene triblock copolymer, and a second layer containing at least one of a styrene-isoprene-styrene triblock copolymer and a styrene-isobutylene diblock copolymer, wherein i) at least one of said first layer and said second layer is a polymer composition further containing a C4 polymer obtained by polymerizing a monomer unit having 4 carbon atoms by more than or equal to 0.5 mass % and less than or equal to 40 mass %, or ii) said first layer further contains a layered clay mineral with an organic compound intercalated therein by 0.1 part by mass to 50 parts by mass relative to 100 parts by mass of the polymer component, or iii) said first layer further contains at least one kind of rubber component selected from the group consisting of a natural rubber, an isoprene rubber and a butyl rubber by more than or equal to 60 mass % and less than or equal to 95 mass % and said second layer further contains at least one kind of rubber component selected from the group consisting of a natural rubber, an isoprene rubber and a butyl rubber by more than or equal to 15 mass % and less than or equal to 90 mass %, said second layer is arranged to come into contact with a rubber layer of the carcass ply, and said inner liner has a thickness Ge at a shoulder position Pe exceeding 100% and being less than or equal to 500% of a thickness Gc at a crown central position Pc. i) at least one of said first layer and said second layer is a polymer composition further containing a C4 polymer obtained by polymerizing a monomer unit having 4 carbon atoms by more than or equal to 0.5 mass % and less than or equal to 40 mass %, or ii) said first layer further contains a layered clay mineral with an organic compound intercalated therein by 0.1 part by mass to 50 parts by mass relative to 100 parts by mass of the polymer component, or iii) said first layer further contains at least one kind of rubber component selected from the group consisting of a natural rubber, an isoprene rubber and a butyl rubber by more than or equal to 60 mass % and less than or equal to 95 mass % and said second layer further contains at least one kind of rubber component selected from the group consisting of a natural rubber, an isoprene rubber and a butyl rubber by more than or equal to 15 mass % and less than or equal to 90 mass %,