An ultrasound imaging system comprising: a display configured to display at least one of a plurality of ultrasound images generated by an ultrasound probe for transmitting-receiving ultrasound signals, wherein the plurality of ultrasound images are contrast-enhanced ultrasound images; a user interface configured to receive a user input via at least one user control, wherein the user input indicates a first region of interest within the at least one image of the plurality of ultrasound images, wherein the first ROI includes less than an entirety of the at least one of the plurality of ultrasound images; and at least one processor in communication with the user interface, the at least one processor configured to: process at least some of the plurality of ultrasound images with a first processing technique, wherein the first processing technique is a contrast enhanced ultrasound processing technique; process in the first ROI at least some of the plurality of ultrasound images with a second processing technique, wherein the second processing technique has a higher spatial resolution and a lower temporal resolution than the first processing technique, wherein the second processing technique is a super resolution imaging processing technique; and generate a confidence score based, at least in part, on the second processing technique, wherein the confidence score is an indication of at least one of: a sufficient number of frames having been accumulated for generating the SRI image; and a sufficiently low motion during frame accumulation, wherein the display is further configured to display the at least some of the plurality of ultrasound images processed with the first processing technique and the at least some of the plurality of ultrasound images processed with the second processing technique, and wherein the generated confidence score and/or a qualitative indication of the generated confidence score is provided to the user. a display configured to display at least one of a plurality of ultrasound images generated by an ultrasound probe for transmitting-receiving ultrasound signals, wherein the plurality of ultrasound images are contrast-enhanced ultrasound images; a user interface configured to receive a user input via at least one user control, wherein the user input indicates a first region of interest within the at least one image of the plurality of ultrasound images, wherein the first ROI includes less than an entirety of the at least one of the plurality of ultrasound images; and at least one processor in communication with the user interface, the at least one processor configured to: process at least some of the plurality of ultrasound images with a first processing technique, wherein the first processing technique is a contrast enhanced ultrasound processing technique; process in the first ROI at least some of the plurality of ultrasound images with a second processing technique, wherein the second processing technique has a higher spatial resolution and a lower temporal resolution than the first processing technique, wherein the second processing technique is a super resolution imaging processing technique; and generate a confidence score based, at least in part, on the second processing technique, wherein the confidence score is an indication of at least one of: a sufficient number of frames having been accumulated for generating the SRI image; and a sufficiently low motion during frame accumulation, process at least some of the plurality of ultrasound images with a first processing technique, wherein the first processing technique is a contrast enhanced ultrasound processing technique; process in the first ROI at least some of the plurality of ultrasound images with a second processing technique, wherein the second processing technique has a higher spatial resolution and a lower temporal resolution than the first processing technique, wherein the second processing technique is a super resolution imaging processing technique; and generate a confidence score based, at least in part, on the second processing technique, wherein the confidence score is an indication of at least one of: a sufficient number of frames having been accumulated for generating the SRI image; and a sufficiently low motion during frame accumulation, wherein the display is further configured to display the at least some of the plurality of ultrasound images processed with the first processing technique and the at least some of the plurality of ultrasound images processed with the second processing technique, and wherein the generated confidence score and/or a qualitative indication of the generated confidence score is provided to the user.