mhurhangee/ep-ind-claims huggingface dataset:
An in-vitro method for transferring one or more nucleic acids into activated NK cells with a pseudotyped retroviral vector particle or a virus-like particle thereof, comprising the steps a) Activation of NK cells, and b) Addition of said pseudotyped retroviral vector particle or virus-like particle thereof to said activated NK cells, wherein said pseudotyped retroviral vector particle or virus-like particle thereof comprises a modified baboon endogenous retrovirus (BaEV) envelope glycoprotein that is able of binding to and fusing with a hematopoietic cell membrane, thereby transferring biological material into said activated NK cells, wherein said modified baboon endogenous retrovirus (BaEV) envelope glycoprotein that is able of binding to and fusing with a hematopoietic cell membrane is: a chimeric envelope glycoprotein which comprises or consists in a fusion of the transmembrane and extracellular domain of a baboon endogenous retrovirus (BaEV) envelope glycoprotein and the cytoplasmic tail domain of a murine leukemia virus envelope glycoprotein; or a modified BaEV envelope glycoprotein wherein the cytoplasmic tail domain is devoid of the fusion inhibitory R peptide. a) Activation of NK cells, and b) Addition of said pseudotyped retroviral vector particle or virus-like particle thereof to said activated NK cells, wherein said pseudotyped retroviral vector particle or virus-like particle thereof comprises a modified baboon endogenous retrovirus (BaEV) envelope glycoprotein that is able of binding to and fusing with a hematopoietic cell membrane, thereby transferring biological material into said activated NK cells, wherein said modified baboon endogenous retrovirus (BaEV) envelope glycoprotein that is able of binding to and fusing with a hematopoietic cell membrane is: a chimeric envelope glycoprotein which comprises or consists in a fusion of the transmembrane and extracellular domain of a baboon endogenous retrovirus (BaEV) envelope glycoprotein and the cytoplasmic tail domain of a murine leukemia virus envelope glycoprotein; or a modified BaEV envelope glycoprotein wherein the cytoplasmic tail domain is devoid of the fusion inhibitory R peptide. a chimeric envelope glycoprotein which comprises or consists in a fusion of the transmembrane and extracellular domain of a baboon endogenous retrovirus (BaEV) envelope glycoprotein and the cytoplasmic tail domain of a murine leukemia virus envelope glycoprotein; or a modified BaEV envelope glycoprotein wherein the cytoplasmic tail domain is devoid of the fusion inhibitory R peptide.
An apparatus for determining fluid flow in a pipe, the apparatus comprising: a fluid nozzle in fluid communication with the pipe and having a surface with a contour; a transit time ultrasonic flow meter disposed downstream of the nozzle and employing at least one acoustic path in communication with the fluid in the pipe; and characterised in that the contour is defined by a compound of two ellipsoidal bodies of revolution to prevent negative pressure gradients in the fluid along the surface of the nozzle as the fluid flows through the nozzle. a fluid nozzle in fluid communication with the pipe and having a surface with a contour; a transit time ultrasonic flow meter disposed downstream of the nozzle and employing at least one acoustic path in communication with the fluid in the pipe; and characterised in that the contour is defined by a compound of two ellipsoidal bodies of revolution to prevent negative pressure gradients in the fluid along the surface of the nozzle as the fluid flows through the nozzle.
An apparatus having unlocking and actuating functions comprising: a body containing a locking piston, a cavity behind the locking piston, an actuating piston, and a piston lock; pressure relief means configured to relieve pressure behind the locking piston to enable the movement of air from behind the locking piston to any other area of the apparatus; and characterised by a hydrophobic vent in the apparatus, configured to allow passage of air between the interior and exterior of the apparatus, thereby equalizing air pressure when the apparatus is not in the water, while preventing water entry upon immersion. a body containing a locking piston, a cavity behind the locking piston, an actuating piston, and a piston lock; pressure relief means configured to relieve pressure behind the locking piston to enable the movement of air from behind the locking piston to any other area of the apparatus; and characterised by a hydrophobic vent in the apparatus, configured to allow passage of air between the interior and exterior of the apparatus, thereby equalizing air pressure when the apparatus is not in the water, while preventing water entry upon immersion.
An air cleaner apparatus mounted in a vehicle having an engine room encapsulation structure formed to surround an upper side, a lower side, lateral sides, and a rear side of an engine in an engine room, the air cleaner apparatus comprising: a filter provided at a side of the engine room encapsulation structure to receive air from an outside of the engine room encapsulation structure, and remove foreign matter from the air; a housing enclosing the filter and receiving the air passed through the filter; and an air intake hose connected to an end of the housing and configured for supplying the air passed through the housing to the engine as intake air, wherein the engine room encapsulation structure has a side having a hole formed therein for making an inside and an outside of the engine room encapsulation structure to be in communication with each other therethrough, wherein the filter and the housing are arranged such that the hole is positioned between the filter and an opened side of the housing, and wherein the air passed through the filter is introduced to the housing through the hole. a filter provided at a side of the engine room encapsulation structure to receive air from an outside of the engine room encapsulation structure, and remove foreign matter from the air; a housing enclosing the filter and receiving the air passed through the filter; and an air intake hose connected to an end of the housing and configured for supplying the air passed through the housing to the engine as intake air, wherein the engine room encapsulation structure has a side having a hole formed therein for making an inside and an outside of the engine room encapsulation structure to be in communication with each other therethrough, wherein the filter and the housing are arranged such that the hole is positioned between the filter and an opened side of the housing, and wherein the air passed through the filter is introduced to the housing through the hole.
A fragrance composition comprising a fragrance compound of Formula, or a stereoisomer thereof: wherein R is C R b; Rb is selected from CH CH 3, CH 2 CH 3, and CH 2 OH. R is C R b; Rb is selected from CH CH 3, CH 2 CH 3, and CH 2 OH.
A delivery system for a self-expanding stent, said system comprises: a guide wire tube located coaxially with an outer sheath, said guide wire tube and said outer sheath including a distal and proximal end; a pusher positioned at a proximal end of said guide wire tube; and a slider located coaxially with said guide wire tube and positioned within and contacting an inner diameter of said stent; wherein the stent is constrained within an inner diameter of said outer sheath, said outer sheath is configured to be retracted relative to the guide wire tube to enable stent deployment and said slider is free to rotate about and move longitudinally along said guide wire tube, thereby enabling said stent to move distally or rotate within said outer sheath, characterised in that the delivery system further comprises a distal stop attached to said guide wire tube at a position distal to said slider. a guide wire tube located coaxially with an outer sheath, said guide wire tube and said outer sheath including a distal and proximal end; a pusher positioned at a proximal end of said guide wire tube; and a slider located coaxially with said guide wire tube and positioned within and contacting an inner diameter of said stent; wherein the stent is constrained within an inner diameter of said outer sheath, said outer sheath is configured to be retracted relative to the guide wire tube to enable stent deployment and said slider is free to rotate about and move longitudinally along said guide wire tube, thereby enabling said stent to move distally or rotate within said outer sheath, characterised in that the delivery system further comprises a distal stop attached to said guide wire tube at a position distal to said slider. a pusher positioned at a proximal end of said guide wire tube; and a slider located coaxially with said guide wire tube and positioned within and contacting an inner diameter of said stent; wherein the stent is constrained within an inner diameter of said outer sheath, said outer sheath is configured to be retracted relative to the guide wire tube to enable stent deployment and said slider is free to rotate about and move longitudinally along said guide wire tube, thereby enabling said stent to move distally or rotate within said outer sheath, characterised in that the delivery system further comprises a distal stop attached to said guide wire tube at a position distal to said slider.
An instrument for elemental analysis comprising: a combustion tube that has a sample injection port with an open top and is for combusting a liquid sample therein; a sample injection mechanism having a nozzle and a slider, the nozzle being for injecting a sample into the combustion tube, the slider being configured to slide between a first position and a second position above the combustion tube, the sample injection mechanism being configured so that the sample injection port of the combustion tube is sealed in a state where the slider is positioned at the first position, and the sample injection port is unsealed and the nozzle is positioned above the sample injection port in a state where the slider is positioned at the second position; a carrier gas supply flow path communicating with inside of the combustion tube to supply carrier gas into the combustion tube; a pressure sensor that detects pressure in the carrier gas supply flow path; a detector for detecting components in sample gas flowing out of the combustion tube; and an arithmetic part configured to determine an abnormality degree of a state in a system between the combustion tube and the detector based on a change in pressure, which is detected by the pressure sensor, at the time when the slider of the sample injection mechanism slides from the first position to the second position. a combustion tube that has a sample injection port with an open top and is for combusting a liquid sample therein; a sample injection mechanism having a nozzle and a slider, the nozzle being for injecting a sample into the combustion tube, the slider being configured to slide between a first position and a second position above the combustion tube, the sample injection mechanism being configured so that the sample injection port of the combustion tube is sealed in a state where the slider is positioned at the first position, and the sample injection port is unsealed and the nozzle is positioned above the sample injection port in a state where the slider is positioned at the second position; a carrier gas supply flow path communicating with inside of the combustion tube to supply carrier gas into the combustion tube; a pressure sensor that detects pressure in the carrier gas supply flow path; a detector for detecting components in sample gas flowing out of the combustion tube; and an arithmetic part configured to determine an abnormality degree of a state in a system between the combustion tube and the detector based on a change in pressure, which is detected by the pressure sensor, at the time when the slider of the sample injection mechanism slides from the first position to the second position.
A tubular reaction vessel through which process material can flow in a continuous manner entering through an inlet and leaving via an outlet wherein an agitator is provided inside the vessel which is capable of reciprocal movement through an arc to create agitation about the axis of the tubular vessel in a radial direction to the direction of flow of the process material wherein the reciprocal movement is produced by a partial, full or multiple full rotation of the agitator in a single direction followed by a stop and followed by partial, full or multiple full rotation of the agitator in the opposite direction wherein the agitator comprises a probe within the tubular reactor extending substantially along the length of the reactor and through holes are cut into the body of the agitator
A connector (10, 20, 90, 410A, 410B, 510A, 510B, 610A, 610B, 710, 1310) comprising: a first piece (14, 414A, 414B, 514A, 514B, 614A, 614B, 714B, 1314); a piercing member (22, 422A, 422B, 522A, 522B, 622B, 722B, 822) attached to the first piece (14, 414A, 414B, 514A, 514B, 614A, 614B, 714B, 1314); and a second piece (12, 312, 412A, 412B, 512A, 512B, 612A, 612B, 712B, 812, 912, 1312, 1412), the piercing member (22, 422A, 422B, 522A, 522B, 622B, 722B, 822) being slidingly receivable within the second piece (12, 312, 412A, 412B, 512A, 512B, 612A, 612B, 712B, 812, 912, 1312, 1412); wherein the piercing member (22, 422A, 422B, 522A, 522B, 622B, 722B, 822) and the second piece (12, 312, 412A, 412B, 512A, 512B, 612A, 612B, 712B, 812, 912, 1312, 1412) are movable relative to each other between a first position where the second piece (12, 312, 412A, 412B, 512A, 512B, 612A, 612B, 712B, 812, 912, 1312, 1412) closes a flow port and a second position where the flow port is open; characterized in that the first piece (14, 414A, 414B, 514A, 514B, 614A, 614B, 714B, 1314) further includes a locking mechanism adapted to lockingly connect the first piece (14, 414A, 414B, 514A, 514B, 614A, 614B, 714B, 1314) to a device (94, 794, 894) when engaged therewith, thereby permanently locking the first piece (14, 414A, 414B, 514A, 514B, 614A, 614B, 714B, 1314) to the device (94, 794, 894) and preventing subsequent disconnection of the first piece (14, 414A, 414B, 514A, 514B, 614A, 614B, 714B, 1314) and the device (94, 794, 894). a first piece (14, 414A, 414B, 514A, 514B, 614A, 614B, 714B, 1314); a piercing member (22, 422A, 422B, 522A, 522B, 622B, 722B, 822) attached to the first piece (14, 414A, 414B, 514A, 514B, 614A, 614B, 714B, 1314); and a second piece (12, 312, 412A, 412B, 512A, 512B, 612A, 612B, 712B, 812, 912, 1312, 1412), the piercing member (22, 422A, 422B, 522A, 522B, 622B, 722B, 822) being slidingly receivable within the second piece (12, 312, 412A, 412B, 512A, 512B, 612A, 612B, 712B, 812, 912, 1312, 1412); wherein the piercing member (22, 422A, 422B, 522A, 522B, 622B, 722B, 822) and the second piece (12, 312, 412A, 412B, 512A, 512B, 612A, 612B, 712B, 812, 912, 1312, 1412) are movable relative to each other between a first position where the second piece (12, 312, 412A, 412B, 512A, 512B, 612A, 612B, 712B, 812, 912, 1312, 1412) closes a flow port and a second position where the flow port is open; characterized in that the first piece (14, 414A, 414B, 514A, 514B, 614A, 614B, 714B, 1314) further includes a locking mechanism adapted to lockingly connect the first piece (14, 414A, 414B, 514A, 514B, 614A, 614B, 714B, 1314) to a device (94, 794, 894) when engaged therewith, thereby permanently locking the first piece (14, 414A, 414B, 514A, 514B, 614A, 614B, 714B, 1314) to the device (94, 794, 894) and preventing subsequent disconnection of the first piece (14, 414A, 414B, 514A, 514B, 614A, 614B, 714B, 1314) and the device (94, 794, 894).
Laser processing machine arrangement comprising - a laser processing head for the laser processing of a workpiece, wherein during operation of the laser processing head laser radiation is emitted radially from a processing zone on the workpiece, and - a laser protection wall, which surrounds the laser processing head and a danger zone around the laser processing head and which shields the laser radiation which is emitted radially during operation from the processing zone, wherein at least a portion of the laser protection wall is constructed as a slat region with a plurality of slat elements (31; 31a-31d) which are impermeable to the laser radiation, wherein the slat elements (31; 31a-31d) overlap along a first direction which extends perpendicularly to the local propagation direction of the laser radiation, and wherein the slat elements (31; 31a-31d) are arranged offset with respect to each other in a second direction so that free viewing gaps remain between the slat elements (31; 31a-31d) in a third direction which extends perpendicularly to the second direction, characterised in that the arrangement has an automation device at which unprocessed workpieces can be transferred into the arrangement and/or processed workpieces can be transferred out of the arrangement, in that the arrangement further has an operator stand from which an operator can control the arrangement, and in that the slat region is arranged in such a manner that an operator on the operator stand can look in the third direction through the slat region at the automation device. - a laser processing head for the laser processing of a workpiece, wherein during operation of the laser processing head laser radiation is emitted radially from a processing zone on the workpiece, and - a laser protection wall, which surrounds the laser processing head and a danger zone around the laser processing head and which shields the laser radiation which is emitted radially during operation from the processing zone,
A stabilising arrangement to support an object above four ground engaging means (5c, 6c, 7c, 8c), the arrangement including an interconnection means interconnecting at least three lever parts including a first lever part, a second lever part and a third lever part, each of the lever parts includes a beam portion (5a, 6a, 7a) connected to the interconnection means by a respective pivot having a respective pivot axis (5h, 6h, 7h), each ground engaging means being attached to or integral with one of said at least three lever parts where one of said four ground engaging means is connected to the first lever part, one other of said four ground engaging means is connected to the third lever part and at least one other of said four ground engaging means is connected to the second lever part, the first pivot axis and the third pivot axis being at an angle of up to thirty degrees of parallel to each other, and within thirty degrees of perpendicular to the second pivot axis, the interconnection means including a base portion to which the beam portions of the legs are pivotally connected. the second lever part including first and second engaging regions, the first engaging region being located on the opposite side of the second pivot axis to the second engaging region in plan view, the first lever part including a first engaging region, in use engaged with the second engaging region of the second lever part, the third lever part including a second engaging region, in use engaged with the first engaging region of the second lever part, such that rotation of the first lever part drives a rotation of the second lever part which drives rotation of the third lever part in a substantially opposite direction to the first lever part to permit a warp displacement of the four ground engaging means, the stabilising arrangement thereby providing support of the object on uneven ground, characterised in that the stabilising arrangement includes a stop (4e; 5b, 8j, 6b, 5j, 7b, 6j, 8b, 7j) such that interference between the stop and one or more of the lever parts (5, 6, 7) limits the rotation of each lever part about its pivot axis to thereby limit an articulation or warp displacement of the lever parts.
Steam hairdressing appliance comprising: - two jaws (2, 3) disposed opposite each other of which a first jaw comprising a first longitudinal casing receiving a first treatment surface, and a second jaw comprising a second treatment surface, and a second jaw comprising a second longitudinal casing receiving a second treatment surface, the surfaces (4, 5) being intended to grip a strand of hair, - a liquid reservoir, - at least the first casing comprising means for steaming the liquid in fluid communication with the reservoir and the means for distributing the steam in communication with the steaming means, said first casing having an inner surface opposite the steaming means, characterised in that at least the first casing comprises, on the inner surface thereof, a first series of protruding lines parallel to a first axis and a second series of protruding lines parallel to a second axis forming a non-zero angle (α) with the first axis, and in that at least one part of the second series of protruding lines are crossed with at least one part of the first series of protruding lines to form at least one air compartment. - two jaws (2, 3) disposed opposite each other of which a first jaw comprising a first longitudinal casing receiving a first treatment surface, and a second jaw comprising a second treatment surface, and a second jaw comprising a second longitudinal casing receiving a second treatment surface, the surfaces (4, 5) being intended to grip a strand of hair, - a liquid reservoir, - at least the first casing comprising means for steaming the liquid in fluid communication with the reservoir and the means for distributing the steam in communication with the steaming means, said first casing having an inner surface opposite the steaming means,