A portable therapeutic fluid delivery device for delivering a therapeutic fluid into a body of a patient comprising: at least one housing securable to the body of the patient; a reservoir for containing the therapeutic fluid, said reservoir coupled to the at least one housing; a therapeutic fluid dispensing mechanism coupled to said reservoir; a memory component adapted for storing a value corresponding to a therapeutic fluid delivery dose; a controller adapted for initiating a delivery of the therapeutic fluid by activating the therapeutic fluid dispensing mechanism, said controller further adapted for limiting the delivery of the therapeutic fluid based on the value stored in the memory component; a bolus delivery button configured to signal the controller to initiate the delivery of the therapeutic fluid into the body of the patient; an inadvertent initiation prevention mechanism adapted for preventing the patient from inadvertently activating the bolus delivery button. characterized in that: the bolus delivery button is one of two or more bolus delivery buttons (15,16), with a first of the bolus delivery buttons (15,16) being positioned on a first side of the therapeutic fluid delivery device and a second of the bolus delivery buttons (15,16) being positioned on a second side of the therapeutic fluid delivery device; and the inadvertent initiation prevention mechanism either prevents the controller from initiating the delivery of the therapeutic fluid into the body of the patient unless the patient activates the two or more bolus delivery buttons (15,16) substantially simultaneously or prevents the controller from initiating the delivery of the therapeutic fluid into the body of the patient unless the patient activates the two or more bolus delivery buttons (15,16) according to an activation sequence. at least one housing securable to the body of the patient; a reservoir for containing the therapeutic fluid, said reservoir coupled to the at least one housing; a therapeutic fluid dispensing mechanism coupled to said reservoir; a memory component adapted for storing a value corresponding to a therapeutic fluid delivery dose; a controller adapted for initiating a delivery of the therapeutic fluid by activating the therapeutic fluid dispensing mechanism, said controller further adapted for limiting the delivery of the therapeutic fluid based on the value stored in the memory component; a bolus delivery button configured to signal the controller to initiate the delivery of the therapeutic fluid into the body of the patient; an inadvertent initiation prevention mechanism adapted for preventing the patient from inadvertently activating the bolus delivery button. characterized in that: the bolus delivery button is one of two or more bolus delivery buttons (15,16), with a first of the bolus delivery buttons (15,16) being positioned on a first side of the therapeutic fluid delivery device and a second of the bolus delivery buttons (15,16) being positioned on a second side of the therapeutic fluid delivery device; and the inadvertent initiation prevention mechanism either prevents the controller from initiating the delivery of the therapeutic fluid into the body of the patient unless the patient activates the two or more bolus delivery buttons (15,16) substantially simultaneously or prevents the controller from initiating the delivery of the therapeutic fluid into the body of the patient unless the patient activates the two or more bolus delivery buttons (15,16) according to an activation sequence.