A delivery system for delivery of an interventional device in an intravascular procedure, the delivery system comprising: a handle having one or more controls (312, 314); a delivery catheter having a proximal end and a distal end, the proximal end being coupled to the handle, the delivery catheter having a proximal section and a distal section, wherein at least the distal section is configured to selectively form a compound curve to enable positioning of the distal end relative to a targeted intravascular treatment site, and wherein the compound curve includes a first pre-formed curve at a proximal portion of the distal section and a second pre-formed curve at a distal portion of the distal section; a series of control lines (326, 328, 330, 332), each operatively coupled to a control (312, 314) of the handle and each extending from the handle through a wall lumen of the delivery catheter toward the distal end; a distal coupler disposed at or near the distal end of the delivery catheter, one or more control lines (326, 328) extending to the distal coupler and engaging with the distal coupler such that tensioning of the one or more control lines (326, 328) changes position of the distal coupler to thereby form or adjust the compound curve; and an intermediate coupler disposed at the distal section at a location proximal of the distal coupler, and further comprising one or more intermediate control lines (330, 332), each operatively coupled to a control of the handle and extending to engage with the intermediate coupler and to enable manipulation of the intermediate coupler, manipulation of the intermediate coupler thereby controlling the first pre-formed curve and manipulation of the distal coupler thereby controlling the second pre-formed curve. a handle having one or more controls (312, 314); a delivery catheter having a proximal end and a distal end, the proximal end being coupled to the handle, the delivery catheter having a proximal section and a distal section, wherein at least the distal section is configured to selectively form a compound curve to enable positioning of the distal end relative to a targeted intravascular treatment site, and wherein the compound curve includes a first pre-formed curve at a proximal portion of the distal section and a second pre-formed curve at a distal portion of the distal section; wherein at least the distal section is configured to selectively form a compound curve to enable positioning of the distal end relative to a targeted intravascular treatment site, and wherein the compound curve includes a first pre-formed curve at a proximal portion of the distal section and a second pre-formed curve at a distal portion of the distal section; a series of control lines (326, 328, 330, 332), each operatively coupled to a control (312, 314) of the handle and each extending from the handle through a wall lumen of the delivery catheter toward the distal end; a distal coupler disposed at or near the distal end of the delivery catheter, one or more control lines (326, 328) extending to the distal coupler and engaging with the distal coupler such that tensioning of the one or more control lines (326, 328) changes position of the distal coupler to thereby form or adjust the compound curve; and an intermediate coupler disposed at the distal section at a location proximal of the distal coupler, and further comprising one or more intermediate control lines (330, 332), each operatively coupled to a control of the handle and extending to engage with the intermediate coupler and to enable manipulation of the intermediate coupler, manipulation of the intermediate coupler thereby controlling the first pre-formed curve and manipulation of the distal coupler thereby controlling the second pre-formed curve.