mhurhangee/ep-ind-claims huggingface dataset:
A process for the hydroformylation of olefins to aldehydes, the process comprising: a. Hydroformylating one or more olefins with hydrogen and carbon monoxide in the presence of a ligand-rhodium catalyst in a reaction zone; b. Recovering a reactor effluent from the reaction zone, the reactor effluent comprising product aldehyde and the ligand-rhodium catalyst; c. Passing the reactor effluent and a strip gas to a vaporiser, wherein the strip gas comprises carbon monoxide and is formed from a recycle strip gas stream and a make-up strip gas stream, wherein the product aldehyde is vaporised into the strip gas in the vaporiser resulting in a vapour mixture, comprising the strip gas and the product aldehyde, and a liquid mixture, comprising the ligand-rhodium catalyst; d. Recovering the liquid mixture and recycling the ligand-rhodium catalyst to the reaction zone; e. Recovering the vapour mixture and separating the product aldehyde from the vapour mixture to create a product aldehyde stream and the recycle strip gas stream for returning to step (c); f. Purging a portion of the recycle strip gas as a purged strip gas stream; and g. Combining the purged strip gas stream with a hydrogen-containing stream to create a re-formed syngas stream, comprising hydrogen and carbon monoxide, and feeding the re-formed syngas stream to the reaction zone in step (a). a. Hydroformylating one or more olefins with hydrogen and carbon monoxide in the presence of a ligand-rhodium catalyst in a reaction zone; b. Recovering a reactor effluent from the reaction zone, the reactor effluent comprising product aldehyde and the ligand-rhodium catalyst; c. Passing the reactor effluent and a strip gas to a vaporiser, wherein the strip gas comprises carbon monoxide and is formed from a recycle strip gas stream and a make-up strip gas stream, wherein the product aldehyde is vaporised into the strip gas in the vaporiser resulting in a vapour mixture, comprising the strip gas and the product aldehyde, and a liquid mixture, comprising the ligand-rhodium catalyst; d. Recovering the liquid mixture and recycling the ligand-rhodium catalyst to the reaction zone; e. Recovering the vapour mixture and separating the product aldehyde from the vapour mixture to create a product aldehyde stream and the recycle strip gas stream for returning to step (c); f. Purging a portion of the recycle strip gas as a purged strip gas stream; and g. Combining the purged strip gas stream with a hydrogen-containing stream to create a re-formed syngas stream, comprising hydrogen and carbon monoxide, and feeding the re-formed syngas stream to the reaction zone in step (a).
A compound selected from the group consisting of TLR9 antagonists and inhibitors of TLR9 expression for use in the treatment of rhabdomyolysis in a subject in need thereof.
A method of wireless communication, comprising: receiving, by a user equipment (120, 905, 1005), UE, an indication of a traffic type, wherein the indication is received via a first radiofrequency, RF, band; configuring the UE to switch from a first antenna subarray operation that uses a first set of antenna subarrays to a second antenna subarray operation that uses a second set of antenna subarrays for communication of high priority traffic based at least in part on receiving the indication of the traffic type, wherein the second antenna subarray operation uses a second RF band for a communication, wherein the second antenna subarray operation uses more active antenna subarrays than the first antenna subarray operation; and transmitting, by the UE, the communication using the second antenna subarray operation. receiving, by a user equipment (120, 905, 1005), UE, an indication of a traffic type, wherein the indication is received via a first radiofrequency, RF, band; configuring the UE to switch from a first antenna subarray operation that uses a first set of antenna subarrays to a second antenna subarray operation that uses a second set of antenna subarrays for communication of high priority traffic based at least in part on receiving the indication of the traffic type, wherein the second antenna subarray operation uses a second RF band for a communication, wherein the second antenna subarray operation uses more active antenna subarrays than the first antenna subarray operation; and transmitting, by the UE, the communication using the second antenna subarray operation.
A method for securely connecting to a remote server, comprising: receiving, by a client, a request to connect to a remote server associated with a domain name; in response to receiving the request to connect to a remote server associated with the domain name, obtaining by the client a domain name resolution from a Domain Name System, DNS, server wherein the domain name resolution includes an Internet Protocol, IP, address for the remote server and a DNS service record for the domain name including at least one parameter indicating that the remote server supports at least one IP layer security protocol; determining, by the client that the remote server supports the at least one IP layer security protocol based on the at least one parameter indicating that the remote server supports the at least one IP layer security protocol included in the DNS service record included in the DNS resolution obtained from the DNS server; performing, by the client, a key exchange protocol with the remote server to generate at least one shared secret in response to determining that the remote server supports the at least one IP layer security protocol; and connecting, by the client, to the remote server using the at least one shared secret in the at least one IP layer security protocol to establish a secure connection between the client at one endpoint of the secure connection and the remote server at another endpoint of the secure connection. receiving, by a client, a request to connect to a remote server associated with a domain name; in response to receiving the request to connect to a remote server associated with the domain name, obtaining by the client a domain name resolution from a Domain Name System, DNS, server wherein the domain name resolution includes an Internet Protocol, IP, address for the remote server and a DNS service record for the domain name including at least one parameter indicating that the remote server supports at least one IP layer security protocol; determining, by the client that the remote server supports the at least one IP layer security protocol based on the at least one parameter indicating that the remote server supports the at least one IP layer security protocol included in the DNS service record included in the DNS resolution obtained from the DNS server; performing, by the client, a key exchange protocol with the remote server to generate at least one shared secret in response to determining that the remote server supports the at least one IP layer security protocol; and connecting, by the client, to the remote server using the at least one shared secret in the at least one IP layer security protocol to establish a secure connection between the client at one endpoint of the secure connection and the remote server at another endpoint of the secure connection.
A pharmaceutical formulation stable when stored at between 2°C and 8°C for at least six months and which has a viscosity of between 2 and 50 mPa-s (centipoise (cP)) when measured at 25°C with a shear rate in the range of 100,000-250,000 l/sec suitable for parenteral administration to a mammalian subject, comprising: (a) an aqueous solution comprising a buffer system having a pH of 5.0 to 7.0, wherein the buffer system comprises at least one buffering agent selected from the group consisting of citrate or histidine; (b) a monoclonal antibody or fragment thereof that specifically binds to human MASP-2 and comprises (i) a heavy chain variable region comprising the amino acid sequence set forth in SEQ ID NO:2 and (ii) a light chain variable region comprising the amino acid sequence set forth in SEQ ID NO:3, and which antibody or fragment thereof is at a concentration of 50 mg/mL to 250 mg/mL; and (c) a tonicity modifying agent in a sufficient amount for the formulation to be hypertonic. (a) an aqueous solution comprising a buffer system having a pH of 5.0 to 7.0, wherein the buffer system comprises at least one buffering agent selected from the group consisting of citrate or histidine; (b) a monoclonal antibody or fragment thereof that specifically binds to human MASP-2 and comprises (i) a heavy chain variable region comprising the amino acid sequence set forth in SEQ ID NO:2 and (ii) a light chain variable region comprising the amino acid sequence set forth in SEQ ID NO:3, and which antibody or fragment thereof is at a concentration of 50 mg/mL to 250 mg/mL; and (c) a tonicity modifying agent in a sufficient amount for the formulation to be hypertonic.
A computer implemented method for determining whether a region within a web page is in view, the region within the web page being in view when the region is viewable by a user, comprising: providing a first test feature in the region, wherein the first test feature comprises one of: an element, a document, a plugin or an applet; rendering the web page by a client device; varying the position of the first test feature between a position within the region and a region in which the first test feature is known to be not viewable by the user; monitoring, at the client device, a behavioural characteristic relating to the first test feature, wherein the behavioural characteristic is one of: a frame progression rate of the first test feature, a timer clock rate and a rate at which local connections can be made; and determining, by the client device, from the monitored behavioural characteristic whether the region is in view or not in view, wherein the behavioural characteristic varies according to whether the first test feature is in view or not in view. providing a first test feature in the region, wherein the first test feature comprises one of: an element, a document, a plugin or an applet; rendering the web page by a client device; varying the position of the first test feature between a position within the region and a region in which the first test feature is known to be not viewable by the user; monitoring, at the client device, a behavioural characteristic relating to the first test feature, wherein the behavioural characteristic is one of: a frame progression rate of the first test feature, a timer clock rate and a rate at which local connections can be made; and determining, by the client device, from the monitored behavioural characteristic whether the region is in view or not in view, wherein the behavioural characteristic varies according to whether the first test feature is in view or not in view.
A method for use in connection with delivering assets to users of a broadcast network, said broadcast network primarily involving synchronized distribution of broadcast content to multiple users, said method comprising: receiving a request for dissemination of an asset via said broadcast network, said request defining one or more dissemination parameters relating to a desired level of dissemination of said asset, said dissemination parameters specifying an audience size and audience classification for said asset; causing said asset to be delivered via Customer Premise Equipment devices to network users of a plurality of channels to aggregate said network users across said plurality of channels of said broadcast network to satisfy the dissemination parameters; receiving reports from each CPE device; and aggregating reports from said CPE devices to verify actual asset delivery to said users via said CPE devices and determine an actual audience size for said asset; said delivery via each CPE device comprising, for a given CPE: storing said asset, together with metadata identifying said audience classification, in a storage space of the given CPE; selecting said asset based on classification parameters of at least one of said network users associated with the given CPE; identifying, by the given CPE, a break of programming; and inserting said asset into said break. receiving a request for dissemination of an asset via said broadcast network, said request defining one or more dissemination parameters relating to a desired level of dissemination of said asset, said dissemination parameters specifying an audience size and audience classification for said asset; causing said asset to be delivered via Customer Premise Equipment devices to network users of a plurality of channels to aggregate said network users across said plurality of channels of said broadcast network to satisfy the dissemination parameters; receiving reports from each CPE device; and aggregating reports from said CPE devices to verify actual asset delivery to said users via said CPE devices and determine an actual audience size for said asset; said delivery via each CPE device comprising, for a given CPE: storing said asset, together with metadata identifying said audience classification, in a storage space of the given CPE; selecting said asset based on classification parameters of at least one of said network users associated with the given CPE; identifying, by the given CPE, a break of programming; and inserting said asset into said break. storing said asset, together with metadata identifying said audience classification, in a storage space of the given CPE; selecting said asset based on classification parameters of at least one of said network users associated with the given CPE; identifying, by the given CPE, a break of programming; and inserting said asset into said break.
A wireless transmit/receive unit, WTRU, comprising: a processor configured to, on a condition that a first uplink transmission for a master cell group and a second uplink transmission for a secondary cell group are to occur in a same time interval: determine a master cell group power level for transmissions on the master cell group up to a first power level value; determine a secondary cell group power level for transmissions on the secondary cell group up to a second power level value; and on a condition that, for a portion of the time interval, a total of the master cell group power level and the secondary cell group power level exceed a maximum transmit power level, scale the secondary cell group power level to a scaled power level; and a transmitter configured to: transmit the first uplink transmission at the master cell group power level; and transmit the second uplink transmission at the scaled power level. a processor configured to, on a condition that a first uplink transmission for a master cell group and a second uplink transmission for a secondary cell group are to occur in a same time interval: determine a master cell group power level for transmissions on the master cell group up to a first power level value; determine a secondary cell group power level for transmissions on the secondary cell group up to a second power level value; and on a condition that, for a portion of the time interval, a total of the master cell group power level and the secondary cell group power level exceed a maximum transmit power level, scale the secondary cell group power level to a scaled power level; and determine a master cell group power level for transmissions on the master cell group up to a first power level value; determine a secondary cell group power level for transmissions on the secondary cell group up to a second power level value; and on a condition that, for a portion of the time interval, a total of the master cell group power level and the secondary cell group power level exceed a maximum transmit power level, scale the secondary cell group power level to a scaled power level; and a transmitter configured to: transmit the first uplink transmission at the master cell group power level; and transmit the second uplink transmission at the scaled power level. transmit the first uplink transmission at the master cell group power level; and transmit the second uplink transmission at the scaled power level.
Device for monitoring the clamping force acting in a belt webbing, comprising a housing that has a first housing part and a second housing part, a through-guide between the housing parts (2, 3), which through-guide has at least two support surfaces for the belt webbing, a sensor component, which is arranged in the housing and, by being pressed, rests against one of the flat sides of the belt webbing, and a means arranged between the support surfaces for detecting the deflection of the sensor component or the force on the sensor component transversely to the longitudinal direction of the belt, wherein the housing parts (2, 3) are connected to one another at two housing edges (10, 11), wherein the device has an insert fastened to the housing, on which insert guide elements are formed in the region of the support surfaces for the belt webbing, characterized in that the guide elements delimit the width of the support surfaces for the belt webbing by means of the distance between said guide elements in the belt transverse direction.
A composition comprising HFO-1234yf and at least one additional compound selected from the group consisting of HCFC-253fb, HCFC-234ab, HCFC-243fa, HCO-1130a, HCFC-1131, and HCFO-1242zf.
A liner for a household appliance, comprising: a first polymeric capping layer comprising a first pigment additive; and a polymeric base layer coupled to the first polymeric capping layer, the polymeric base layer comprising: one or more polymers; a second pigment additive; characterized by a natural fiber, the natural fiber being present at a concentration of at least 50% by weight of the polymeric base layer, and by a second polymeric capping layer coupled to the first polymeric capping layer such that the first polymeric capping layer is positioned between the polymeric base layer and the second polymeric capping layer, wherein a textured pattern is formed on an outer surface of the second polymeric capping layer, which is thereby utilized as a scratch-resistant layer. a first polymeric capping layer comprising a first pigment additive; and a polymeric base layer coupled to the first polymeric capping layer, the polymeric base layer comprising: one or more polymers; a second pigment additive; characterized by a natural fiber, the natural fiber being present at a concentration of at least 50% by weight of the polymeric base layer, and by one or more polymers; a second pigment additive; characterized by a natural fiber, the natural fiber being present at a concentration of at least 50% by weight of the polymeric base layer, and by a second polymeric capping layer coupled to the first polymeric capping layer such that the first polymeric capping layer is positioned between the polymeric base layer and the second polymeric capping layer, wherein a textured pattern is formed on an outer surface of the second polymeric capping layer, which is thereby utilized as a scratch-resistant layer.
An airfoil comprising: pressure and suction side walls (86, 88) extending in a chord-wise direction between leading and trailing edges (82, 84), the pressure and suction side walls (86, 88) extending in a radial direction to provide an exterior airfoil surface; a core cooling passage (90a, 90b, 90c) arranged between the pressure and suction walls (86, 88) in a thickness direction and extending radially toward a tip; a skin passage having a skin passage height extending in the thickness direction in a range of 0.010-0.200 inches (0.25- 5.08 mm) and a skin passage width, the skin passage being arranged in one of the pressure and suction side walls (86, 88) to form a hot side wall and a cold side wall, wherein the hot side wall defines a portion of the exterior airfoil surface, the cold side wall defines a portion of the core cooling passage (90a, 90b, 90c), and the core cooling passage (90a, 90b, 90c) and the skin passage are configured to have a same direction of fluid flow; and a resupply hole (110; 210; 310; 410; 510; 610; 710; 810; 910; 1010; 1110) which fluidly interconnects the core cooling and skin passages (90a, 90b, 90c, 98), wherein a centerline of the resupply hole (110...1110) is arranged at an acute angle relative to the direction of fluid flow in the core cooling passage (90a, 90b, 90c), and the acute angle lies in a plane parallel to the thickness direction, and the acute angle is in a range of 5°-45°; characterised in that: the skin passage height and/or skin passage width vary along a length in a radial direction, so that the skin passage has an aspect ratio of the skin passage height divided by the skin passage width that varies between 3:1 and 1:5 along the length in a radial direction. pressure and suction side walls (86, 88) extending in a chord-wise direction between leading and trailing edges (82, 84), the pressure and suction side walls (86, 88) extending in a radial direction to provide an exterior airfoil surface; a core cooling passage (90a, 90b, 90c) arranged between the pressure and suction walls (86, 88) in a thickness direction and extending radially toward a tip; a skin passage having a skin passage height extending in the thickness direction in a range of 0.010-0.200 inches (0.25- 5.08 mm) and a skin passage width, the skin passage being arranged in one of the pressure and suction side walls (86, 88) to form a hot side wall and a cold side wall, wherein the hot side wall defines a portion of the exterior airfoil surface, the cold side wall defines a portion of the core cooling passage (90a, 90b, 90c), and the core cooling passage (90a, 90b, 90c) and the skin passage are configured to have a same direction of fluid flow; and a resupply hole (110; 210; 310; 410; 510; 610; 710; 810; 910; 1010; 1110) which fluidly interconnects the core cooling and skin passages (90a, 90b, 90c, 98), wherein a centerline of the resupply hole (110...1110) is arranged at an acute angle relative to the direction of fluid flow in the core cooling passage (90a, 90b, 90c), and the acute angle lies in a plane parallel to the thickness direction, and the acute angle is in a range of 5°-45°;
An antibody-drug conjugate wherein an antitumor compound represented by the following formula: is conjugated to an anti-TROP2 antibody by a thioether bond which is formed at a disulfide bond moiety present in a hinge part of the anti-TROP2 antibody via a linker having a structure represented by the following formula: -L 1 -L 2 -L P -NH-(CH 2)n 1 -L a -(CH 2)n 2 -C(=O)- wherein the anti-TROP2 antibody is connected to the terminal of L 1, the antitumor compound is connected to the carbonyl group of the -(CH 2)n 2 -C(=O)- moiety with the nitrogen atom of the amino group at position 1 as the connecting position, wherein n 1 represents an integer of 0 to 6, n 2 represents an integer of 0 to 5, L 1 represents -(Succinimid-3-yl-N)-(CH 2)n 3 -C(=O)-, wherein n 3 represents an integer of 2 to 8, L 2 represents -NH-(CH 2 CH 2 -O)n 4 -CH 2 CH 2 -C(=O)- or a single bond, wherein n 4 represents an integer of 1 to 6, L P represents a tetrapeptide residue of -GGFG-, L a represents -O- or a single bond, and -(Succinimid-3-yl-N)- has a structure represented by the following formula: which is connected to the anti-TROP2 antibody at position 3 thereof and is connected to a methylene group in the linker structure containing this structure on the nitrogen atom at position 1, wherein the anti-TROP2 antibody comprises CDRH1 consisting of the amino acid sequence of SEQ ID NO: 23, CDRH2 consisting of the amino acid sequence of SEQ ID NO: 24 and CDRH3 consisting of the amino acid sequence of SEQ ID NO: 25 in its heavy chain variable region and CDRL1 consisting of the amino acid sequence of SEQ ID NO: 26, CDRL2 consisting of the amino acid sequence of SEQ ID NO: 27 and CDRL3 consisting of the amino acid sequence of SEQ ID NO: 28 in its light chain variable region.