Tire damage detection system (1,1A,1B) including an acquisition device and a processing device/system (12,12A,12B); wherein the acquisition device is: • installed on board a motor vehicle equipped with two or more wheels fitted with tires; • coupled to a vehicle bus of the motor vehicle; and • configured to - acquire, from the vehicle bus, a signal indicative of a speed of a wheel of the motor vehicle and - output quantities indicative of the wheel speed; and wherein the processing device/system (12,12A,12B) is: • configured to - store a predefined tire damage model that includes a set of predefined thresholds related to different reference wheel speed values and a set of predefined time lengths related to different reference wheel speed values, and - receive, from the acquisition device, the quantities indicative of the wheel speed; and • programmed to - analyse the wheel speed by means of a sliding time window, - select one of the predefined thresholds and one of the predefined time lengths based on a given reference wheel speed value that is a wheel speed value, or an average of wheel speed values, immediately preceding and/or following the third sliding time window, wherein said sliding time window has the predefined time length selected, - detect a maximum value and a minimum value of the wheel speed within the sliding time window, - compute a difference between said maximum and minimum values, - compute a ratio of the difference between said maximum and minimum values to the given reference wheel speed value, and - detect a potential damage to a tire of the wheel of the motor vehicle if the ratio of the difference between said maximum and minimum values to the given reference wheel speed value exceeds the predefined threshold selected. • installed on board a motor vehicle equipped with two or more wheels fitted with tires; • coupled to a vehicle bus of the motor vehicle; and • configured to - acquire, from the vehicle bus, a signal indicative of a speed of a wheel of the motor vehicle and - output quantities indicative of the wheel speed; - acquire, from the vehicle bus, a signal indicative of a speed of a wheel of the motor vehicle and - output quantities indicative of the wheel speed; • configured to - store a predefined tire damage model that includes a set of predefined thresholds related to different reference wheel speed values and a set of predefined time lengths related to different reference wheel speed values, and - receive, from the acquisition device, the quantities indicative of the wheel speed; and - store a predefined tire damage model that includes a set of predefined thresholds related to different reference wheel speed values and a set of predefined time lengths related to different reference wheel speed values, and - receive, from the acquisition device, the quantities indicative of the wheel speed; and • programmed to - analyse the wheel speed by means of a sliding time window, - select one of the predefined thresholds and one of the predefined time lengths based on a given reference wheel speed value that is a wheel speed value, or an average of wheel speed values, immediately preceding and/or following the third sliding time window, wherein said sliding time window has the predefined time length selected, - detect a maximum value and a minimum value of the wheel speed within the sliding time window, - compute a difference between said maximum and minimum values, - compute a ratio of the difference between said maximum and minimum values to the given reference wheel speed value, and - detect a potential damage to a tire of the wheel of the motor vehicle if the ratio of the difference between said maximum and minimum values to the given reference wheel speed value exceeds the predefined threshold selected. - analyse the wheel speed by means of a sliding time window, - select one of the predefined thresholds and one of the predefined time lengths based on a given reference wheel speed value that is a wheel speed value, or an average of wheel speed values, immediately preceding and/or following the third sliding time window, wherein said sliding time window has the predefined time length selected, - detect a maximum value and a minimum value of the wheel speed within the sliding time window, - compute a difference between said maximum and minimum values, - compute a ratio of the difference between said maximum and minimum values to the given reference wheel speed value, and - detect a potential damage to a tire of the wheel of the motor vehicle if the ratio of the difference between said maximum and minimum values to the given reference wheel speed value exceeds the predefined threshold selected.