mhurhangee/ep-ind-claims huggingface dataset:
An airway device (10, 110, 210, 310, 410, 510), for human or animal use, the device includes an airway tube (12, 112, 212, 312, 412, 512) having a first end (14, 114, 214, 314, 414, 514) and a second end (16, 116, 216, 316, 416, 516), the first end of the airway tube is surrounded by a laryngeal cuff (18, 118, 218, 318, 418, 518), the laryngeal cuff includes a back dorsal portion (20, 120, 220, 320, 420, 520), a front face portion (22, 122, 222, 322, 422, 522) and a tip portion (32, 132, 232, 332, 432, 532), wherein the tip portion includes a front face portion and a dorsal portion, the front face portion of the laryngeal cuff is shaped to form an anatomical fit over the laryngeal inlet of a human or animal patient, and to form a seal with the laryngeal inlet of the patient, characterised in that the tip portion includes an unsymmetrical annular sealing bulge (90, 190, 290, 390, 490, 590), wherein the annular sealing bulge is larger on the front face portion of the tip than on the dorsal portion of the tip.
A method of producing a human antibody or binding fragment thereof with desired specificity characterized by isolating B cells from short term oligoclonal cultures of activated B cells that secrete antibodies of IgG isotype comprising the following steps in the sequence: (a) selecting memory B cells that express antibodies against a protein of interest from one or more biological samples on the basis of the expression of at least one cell-surface membrane marker and/or antigen binding, wherein said biological sample is derived from a patient who is suffering from autoimmune-polyendocrinopathy syndrome type 1 (APS-1)/autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), and wherein the cells are depleted from IgM and IgD isotypes; (b) stimulating the selected cells with a first polyclonal B cell activator which is Epstein-Barr virus under cell culture conditions for three to five hours; (c) separating the cells from said activator, wherein the activator is removed by diluting of or washing out; (d) activating the stimulated cells with a second polyclonal B cell activator which is a CpG-based oligonucleotide under cell culture conditions which do not comprise a cytokine; (e) screening the activated cells that express IgG isotype antibodies of interest and preferably; (e') single-cell harvesting of oligoclonal cultures producing the antibody of interest; (f) sequencing and/or cloning the cDNA of at least the variable light and heavy chain regions and optionally constant region of the antibody of interest, wherein the method does not comprise cellular cloning of the B cells. (a) selecting memory B cells that express antibodies against a protein of interest from one or more biological samples on the basis of the expression of at least one cell-surface membrane marker and/or antigen binding, wherein said biological sample is derived from a patient who is suffering from autoimmune-polyendocrinopathy syndrome type 1 (APS-1)/autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), and wherein the cells are depleted from IgM and IgD isotypes; (b) stimulating the selected cells with a first polyclonal B cell activator which is Epstein-Barr virus under cell culture conditions for three to five hours; (c) separating the cells from said activator, wherein the activator is removed by diluting of or washing out; (d) activating the stimulated cells with a second polyclonal B cell activator which is a CpG-based oligonucleotide under cell culture conditions which do not comprise a cytokine; (e) screening the activated cells that express IgG isotype antibodies of interest and preferably; (e') single-cell harvesting of oligoclonal cultures producing the antibody of interest; (f) sequencing and/or cloning the cDNA of at least the variable light and heavy chain regions and optionally constant region of the antibody of interest,
Safety fabric for protective clothing, in particular chainsaw safety clothing, comprising: - a double knitted fabric, and - a number of cut-resistant inlay threads incorporated in the double knitted fabric, wherein the inlay threads are configured to be pulled out of the double knitted fabric upon contact with a running chainsaw, wherein the inlay threads are at predetermined intervals provided with loop portions. - a double knitted fabric, and - a number of cut-resistant inlay threads incorporated in the double knitted fabric, wherein the inlay threads are configured to be pulled out of the double knitted fabric upon contact with a running chainsaw,
An operation control method, comprising: identifying an operation trace applied on a terminal screen by a user; determining whether the operation trace is in a region where a grid path is located, wherein a gap region among application icons on a terminal interface forms the grid path; and executing a shortcut operation corresponding to the operation trace if the operation trace is in the region where the grid path is located; wherein executing the shortcut operation corresponding to the operation trace comprises: matching the operation trace to a preset operation trace, and performing a corresponding shortcut operation based on a matching result. identifying an operation trace applied on a terminal screen by a user; determining whether the operation trace is in a region where a grid path is located, wherein a gap region among application icons on a terminal interface forms the grid path; and executing a shortcut operation corresponding to the operation trace if the operation trace is in the region where the grid path is located; wherein executing the shortcut operation corresponding to the operation trace comprises: matching the operation trace to a preset operation trace, and performing a corresponding shortcut operation based on a matching result.
A cartridge for sensing at least one analyte, said cartridge comprising: a detection channel having a first end and second end; at least one analyte sensor, wherein said analyte sensor comprises at least one sensor electrode and said sensor electrode is within said detection channel between the first end and the second end; a reagent channel, said reagent channel connected to said detection channel between the sensor electrode and the second end; a sample chamber, said sample chamber connected to said detection channel between the sensor electrode and the first end; a first inlet connected to the sample chamber and configured to move a sample from the sample chamber to the detection channel in response to applied pressure; a second inlet connected to the detection channel at the second end; and at least one blister pack for on-board liquid storage, characterized in that said cartridge further comprises a waste compartment connected to said detection channel at the first end, with the second inlet being configured to push at least one of the sample and an assay fluid from the detection channel to the waste compartment in response to applied pressure; and a bubble trap connecting the blister pack to the reagent channel and configured to trap air bubbles from a liquid moving from the blister pack to the reagent channel. a detection channel having a first end and second end; at least one analyte sensor, wherein said analyte sensor comprises at least one sensor electrode and said sensor electrode is within said detection channel between the first end and the second end; a reagent channel, said reagent channel connected to said detection channel between the sensor electrode and the second end; a sample chamber, said sample chamber connected to said detection channel between the sensor electrode and the first end; a first inlet connected to the sample chamber and configured to move a sample from the sample chamber to the detection channel in response to applied pressure; a second inlet connected to the detection channel at the second end; and at least one blister pack for on-board liquid storage, characterized in that said cartridge further comprises a waste compartment connected to said detection channel at the first end, with the second inlet being configured to push at least one of the sample and an assay fluid from the detection channel to the waste compartment in response to applied pressure; and a bubble trap connecting the blister pack to the reagent channel and configured to trap air bubbles from a liquid moving from the blister pack to the reagent channel.
A tilt-trim system (100; 200) for an outboard motor, the tilt-trim system comprising: a tilt-trim device configured to cause the outboard motor to perform a tilt-trim motion; an operating switch configured to operate the tilt-trim device; a sensor configured to detect a position of the outboard motor during the tilt-trim motion, and a controller connected to the tilt-trim device and the operating switch, wherein the controller is configured to determine whether or not an operation of the operating switch has been performed a plurality of times within a predetermined period of time when receiving a signal indicating the operation from the operating switch, is configured to control the tilt-trim device under an automatic control mode such that the tilt-trim device automatically causes the outboard motor to continuously perform the tilt-trim motion within a motion range set in advance when the operation has been performed the plurality of times within the predetermined period of time, is configured to receive a signal indicating the position of the outboard motor from the sensor during the tilt-trim motion under the automatic control mode, is configured to deactivate the tilt-trim device when the outboard motor reaches either a predetermined upper limit or a predetermined lower limit of the motion range, and is configured to change the motion range in accordance with a setting signal for setting the motion range when receiving the setting signal. a tilt-trim device configured to cause the outboard motor to perform a tilt-trim motion; an operating switch configured to operate the tilt-trim device; a sensor configured to detect a position of the outboard motor during the tilt-trim motion, and a controller connected to the tilt-trim device and the operating switch, wherein the controller is configured to determine whether or not an operation of the operating switch has been performed a plurality of times within a predetermined period of time when receiving a signal indicating the operation from the operating switch, is configured to control the tilt-trim device under an automatic control mode such that the tilt-trim device automatically causes the outboard motor to continuously perform the tilt-trim motion within a motion range set in advance when the operation has been performed the plurality of times within the predetermined period of time, is configured to receive a signal indicating the position of the outboard motor from the sensor during the tilt-trim motion under the automatic control mode, is configured to deactivate the tilt-trim device when the outboard motor reaches either a predetermined upper limit or a predetermined lower limit of the motion range, and is configured to change the motion range in accordance with a setting signal for setting the motion range when receiving the setting signal.
A method for processing Hybrid Automatic Repeat Request, hereinafter HARQ, feedback information in a mobile terminal of a mobile communication system in softer handover, wherein the mobile terminal communicates with one base station via two or more sectors (y1-y3) associated with the one base station, the method comprising: transmitting from the mobile terminal the same data packet to the base station through each of the two or more sectors (y1-y3) associated with the one base station; receiving at the mobile terminal an ACK/NACK signal transmitted by the base station for the transmitted data packet from each of the two or more sectors by applying a HARQ transmission scheme, wherein the ACK/NACK signals transmitted through the two or more sectors are the same in the softer handover, and maximal ratio combining the received ACK/NACK signals into one ACK/NACK signal having the highest signal to noise ratio. transmitting from the mobile terminal the same data packet to the base station through each of the two or more sectors (y1-y3) associated with the one base station; receiving at the mobile terminal an ACK/NACK signal transmitted by the base station for the transmitted data packet from each of the two or more sectors by applying a HARQ transmission scheme, wherein the ACK/NACK signals transmitted through the two or more sectors are the same in the softer handover, and maximal ratio combining the received ACK/NACK signals into one ACK/NACK signal having the highest signal to noise ratio.
A patterned neo-epithelium dressing for treating a tissue site having granulation tissue, the patterned neo-epithelium dressing comprising: an interface member having a first side and a second, patient-facing side for placing proximate to the granulation tissue, and wherein the interface member is characterized by a plurality of three-dimensional features formed on the second, patient-facing side of the interface member and comprising a pattern that mimics the pattern of human skin. an interface member having a first side and a second, patient-facing side for placing proximate to the granulation tissue, and wherein the interface member is characterized by a plurality of three-dimensional features formed on the second, patient-facing side of the interface member and comprising a pattern that mimics the pattern of human skin.
Bolt with a trigger for a lock, in which the bolt, which is secured in a prelocked position by a tumbler against displacement into a relocked position, can be displaced into the relocked position by a displacement of the trigger associated with the bolt from a standby position into a release position by pressure on a bolt end face, wherein the trigger has a bearing limb, which is located in a bearing recess of a broad side face of the bolt, and a sensing head, which is arranged in the region of an end face of the bolt and adjoins the bearing limb, characterised by a retaining leg, which is fastened to the sensing head, and extending parallel to and at a distance from the bearing limb, wherein a section of the bolt with reduced material thickness engages in an intermediate space between the bearing limb and the retaining leg both in the ready position and in the released position.
A pharmaceutical composition comprising: 5 to 20 wt-% ezetimibe, 50 to 85 wt-% diluent, 3 to 25 wt-% disintegrant, 2 to 5 wt-% solubility enhancer 1 to 10 wt-% binder, and 0.5 to 1 wt-% lubricant, characterized in that the ezetimibe has a particle size distribution of d(0.9) of 9 μm to 20 μm and d(0.5) of 4 μm to 10 μm wherein the particle size is determined by laser diffraction using the "wet powder method".
Method for measuring the effective atomic number of a material for a predetermined X or gamma spectral band, comprising the steps: a transmission spectrum S a = n 1 a, n 2 a,..., n N a T of a sample of said material in a plurality of energy channels of said spectral band is measured (120, 220); a likelihood function of the effective atomic number and of the thickness of the sample of said material is calculated (130, 230) from the transmission spectrum measured as such and from a plurality of transmission spectra S c = Z p c, e q c, referred to as calibration spectra, obtained for a plurality of samples of calibration materials having known effective atomic numbers and known thicknesses; characterized in that the calibration spectra are interpolated in order to obtain an interpolated calibration spectrum for each effective atomic number belonging to a first interval ([ Z min, Z max]), and in that for each effective atomic number belonging to this interval and each given thickness, a value of said likelihood function is calculated; the effective atomic number ( Ẑ) of said material is estimated (140, 240) on the basis of values of the likelihood function thus obtained. a transmission spectrum S a = n 1 a, n 2 a,..., n N a T of a sample of said material in a plurality of energy channels of said spectral band is measured (120, 220); a likelihood function of the effective atomic number and of the thickness of the sample of said material is calculated (130, 230) from the transmission spectrum measured as such and from a plurality of transmission spectra S c = Z p c, e q c, referred to as calibration spectra, obtained for a plurality of samples of calibration materials having known effective atomic numbers and known thicknesses; characterized in that the calibration spectra are interpolated in order to obtain an interpolated calibration spectrum for each effective atomic number belonging to a first interval ([ Z min, Z max]), and in that for each effective atomic number belonging to this interval and each given thickness, a value of said likelihood function is calculated; the effective atomic number ( Ẑ) of said material is estimated (140, 240) on the basis of values of the likelihood function thus obtained.
An optical fibre network distributor with a housing, in which is arranged a receiving frame, which is provided with clips serving as fastening means for plastic tubes, which each have a claw-like clamping section, into which plastic tubes may be pressed in laterally, wherein the receiving frame has a plurality of support elements, which are arranged next to one another and which each have a plurality of projections offset in the manner of steps, which are arranged above one another and have windows, into which clips are locked, and wherein the support elements are cut from metal sheet and are provided with a web bent away at right angles, which may be screwed to a rear wall of the housing of the optical fibre network distributor, characterised in that the projections of the support elements have a substantially rectangular shape, cut out of which is a substantially rectangular window and each clip has a receiving pocket, which may be slid onto a respective projection on a support element and which has a spring arm with a locking nose, which locks in the window, and wherein the receiving pocket has a straight base wall at the entry opening, which is bent back at both lateral edges in an overall U shape, wherein spaced from the entry opening the spring arm is cut out from the base wall and wherein the two U-shaped edge sections have a rear wall constituting an abutment for a projection.
An electrode for a secondary battery, comprising: a current collector; and at least oneelectrode material mixture layer present on a surface of the current collector, the at least one electrode material mixture layer comprising a negative electrode active material, a conductive agent, and a binder, wherein, the electrode has a property such that in a regression curve obtained by regression analysis of shear strength data according to a cutting depth which are measured whileobliquely cutting the electrode material mixture layer from a surface thereofuntil reaching the current collector using a surface and interfacial cutting analysis system (SAICAS), a ratio of a maximum value (σ max) to a minimum value (σ min) of shear strength is 1.7 or less. a current collector; and at least oneelectrode material mixture layer present on a surface of the current collector, the at least one electrode material mixture layer comprising a negative electrode active material, a conductive agent, and a binder, wherein, the electrode has a property such that in a regression curve obtained by regression analysis of shear strength data according to a cutting depth which are measured whileobliquely cutting the electrode material mixture layer from a surface thereofuntil reaching the current collector using a surface and interfacial cutting analysis system (SAICAS), a ratio of a maximum value (σ max) to a minimum value (σ min) of shear strength is 1.7 or less.
A method of configuring Ethernet connectivity fault management, CFM, in a network including a plurality of nodes (110, 120, 130, 200), the method comprising: configuring a maintenance domain on a first network node; configuring a maintenance association within the maintenance domain on the first network node; configuring, within the maintenance association, a local maintenance endpoint, MEP, on the first network node; storing in a configuration storage at said first network node an identifier and a Media Access Control, MAC, address of a remote MEP for each other node of the plurality of network nodes within said maintenance association, establishing, within a single maintenance association, a point-to-point connection between said local MEP and said remote MEP using said identifier and said Media Access Control, MAC, address of said remote MEP, wherein: each point-to-point connection enables transmission of unicast CFM messages from said local MEP to said remote MEP, and processing of a unicast CFM message received by said first network node from a transmitting remote MEP after determining a source MAC address of the received unicast message matches a MAC address stored in said configuration storage for said transmitting remote MEP. configuring a maintenance domain on a first network node; configuring a maintenance association within the maintenance domain on the first network node; configuring, within the maintenance association, a local maintenance endpoint, MEP, on the first network node; storing in a configuration storage at said first network node an identifier and a Media Access Control, MAC, address of a remote MEP for each other node of the plurality of network nodes within said maintenance association, establishing, within a single maintenance association, a point-to-point connection between said local MEP and said remote MEP using said identifier and said Media Access Control, MAC, address of said remote MEP, wherein: each point-to-point connection enables transmission of unicast CFM messages from said local MEP to said remote MEP, and processing of a unicast CFM message received by said first network node from a transmitting remote MEP after determining a source MAC address of the received unicast message matches a MAC address stored in said configuration storage for said transmitting remote MEP. each point-to-point connection enables transmission of unicast CFM messages from said local MEP to said remote MEP, and processing of a unicast CFM message received by said first network node from a transmitting remote MEP after determining a source MAC address of the received unicast message matches a MAC address stored in said configuration storage for said transmitting remote MEP.
The combination of a roof rack for motor vehicles and a carrier bar unit (12, 14) of a body of a motor vehicle comprising a cross member and leg members arranged on both sides of said cross member, each leg member comprising a support unit, which is adapted to rest on said respective carrier bar unit (12, 14), said support unit comprising a retaining unit adapted to be connected to a mounting section of said carrier bar unit (12, 14), said support unit being adapted to be supported on said respective carrier bar unit (12, 14) and said support unit comprising a first form locking element designed to cooperate with a second form locking element on said respective carrier bar unit (12, 14) upon movement in a locking direction extending essentially parallel to said cross member, characterized in that said first form locking element is arranged on a foot element of said support unit, in that said foot element with said first form locking element is guided for a movement with respect to said support unit by a guiding arrangement, that said first form locking element is movable between an unlocking position, allowing mounting of said roof rack, to a locking position, and that said first form locking element is a retaining protrusion and designed to cooperate with said second form locking element being a recess receiving said retaining protrusion in the locking position, in order to provide a form locking fixation of said support unit with respect to said respective carrier bar unit (12, 14) against movement in directions extending in a plane transverse to said cross member.