A fluid processing system comprising: a. a reusable hardware unit comprising a rotating centrifuge and a pre-programmed controller; b. an integrated, disposable, fluid circuit configured for mounting onto said reusable hardware unit, said circuit comprising i) tubing defining flow paths for movement of the blood, blood components and other fluids through the fluid circuit, ii) one or more fluid processing cassettes (56 a-c)) including flow paths and pneumatically or electrically operated valves controlled by said pre-programmed controller to selectively allow and restrict flow through said flow paths of said cassette and through the tubing of said fluid circuit, iii) a processing chamber mounted on a rotor/spool of said centrifuge and having a sub-chamber where blood or blood components can be separated under the influence of centrifugal force and a sub-chamber where blood components from sub-chamber can be further processed, separated and/or collected; iii) an illumination/ collection container made of a material able to transmit light of a selected wavelength in openable flow communication with a container housing a compound adsorption device arranged downstream thereof; c. a source of a photoactive agent, and d. a container of blood component additive solution associated with the source of photoactive agent wherein said container of blood component additive solution and said source of photoactive agent are connected at one of the fluid processing cassettes to the fluid circuit. a. a reusable hardware unit comprising a rotating centrifuge and a pre-programmed controller; b. an integrated, disposable, fluid circuit configured for mounting onto said reusable hardware unit, said circuit comprising i) tubing defining flow paths for movement of the blood, blood components and other fluids through the fluid circuit, ii) one or more fluid processing cassettes (56 a-c)) including flow paths and pneumatically or electrically operated valves controlled by said pre-programmed controller to selectively allow and restrict flow through said flow paths of said cassette and through the tubing of said fluid circuit, iii) a processing chamber mounted on a rotor/spool of said centrifuge and having a sub-chamber where blood or blood components can be separated under the influence of centrifugal force and a sub-chamber where blood components from sub-chamber can be further processed, separated and/or collected; iii) an illumination/ collection container made of a material able to transmit light of a selected wavelength in openable flow communication with a container housing a compound adsorption device arranged downstream thereof; i) tubing defining flow paths for movement of the blood, blood components and other fluids through the fluid circuit, ii) one or more fluid processing cassettes (56 a-c)) including flow paths and pneumatically or electrically operated valves controlled by said pre-programmed controller to selectively allow and restrict flow through said flow paths of said cassette and through the tubing of said fluid circuit, iii) a processing chamber mounted on a rotor/spool of said centrifuge and having a sub-chamber where blood or blood components can be separated under the influence of centrifugal force and a sub-chamber where blood components from sub-chamber can be further processed, separated and/or collected; iii) an illumination/ collection container made of a material able to transmit light of a selected wavelength in openable flow communication with a container housing a compound adsorption device arranged downstream thereof; c. a source of a photoactive agent, and d. a container of blood component additive solution associated with the source of photoactive agent wherein said container of blood component additive solution and said source of photoactive agent are connected at one of the fluid processing cassettes to the fluid circuit.