mhurhangee/ep-ind-claims huggingface dataset:
An engineered, non-naturally occurring Clustered Regularly Interspersed Short Palindromic Repeat (CRISPR)-CRISPR associated (Cas) (CRISPR-Cas) composition comprising a) one or more CRISPR-Cas polynucleotide sequences comprising a guide RNA which comprises a guide sequence linked to a direct repeat sequence, wherein the guide sequence is capable of hybridizing to a sequence at the target locus, or one or more nucleotide sequences encoding the one or more CRISPR-Cas polynucleotide sequences, and b) a Cpf1 effector protein, or one or more nucleotide sequences encoding the Cpf1 effector protein, wherein the one or more guide sequences hybridize to said sequence at the target locus, and said guide RNA forms a complex with the Cpf1 effector protein, and wherein a Protospacer Adjacent Motif directs binding of the effector complex to the target locus of interest and upon binding of the effector complex to the locus of interest, the effector protein induces modification of the sequences associated with the target locus of interest and wherein the modification is the introduction of a strand break, and the strand break is a staggered cut with a 5' overhang. a) one or more CRISPR-Cas polynucleotide sequences comprising a guide RNA which comprises a guide sequence linked to a direct repeat sequence, wherein the guide sequence is capable of hybridizing to a sequence at the target locus, or one or more nucleotide sequences encoding the one or more CRISPR-Cas polynucleotide sequences, and b) a Cpf1 effector protein, or one or more nucleotide sequences encoding the Cpf1 effector protein,
A fiber optic management unit (10, 10') for a fiber optic distribution device, the fiber optic management unit comprises a base through which the same is mountable to a housing of the fiber optic distribution device and a tray pivotably attached to the base by a hinge, wherein the base comprises a basic body, the basic body of the base having a front side and a back side, wherein the front side of the basic body provides different functional areas, namely an overlength handling area for handling overlength of optical fibers, a splice and/or splitter handling area for handling splices and/or splitters, at least one patch area (19, 20) for handling fiber optic adapters and/or fiber optic connectors and a cable handling area for handling a fiber optic cable; the tray comprises a basic body, the basic body of the tray having a front side and a back side, wherein the back side provides a splice protector handling area for handling splice protectors, wherein the front side provides an overlength handling area for handling overlength of optical fibers, and wherein the basic body of the tray comprises at least one through opening for guiding optical fibers from the front side to the back side of the basic body of the tray.
A process for the preparation of alkali metal salts of racemic α-amino acids of the general formula R 1 -CH(NH 2)-COOH in which R 1 is selected from hydrogen, CH 3, C 2 H 5, CH(CH 3) 2, (CH 2) 2 COOH and CH 2 OH, wherein an alkali metal salt of the corresponding α-ketocarboxylic acid or glyoxalic acid is reacted in the presence of at least one heterogeneous catalyst, which comprises at least one transition metal, in the presence of hydrogen with at least one nitrogen compound at temperatures in the range from 50 to 200°C, where the nitrogen compound is selected from primary and secondary amines and ammonia.
Light guide for illuminating a display device in a timepiece into which light produced by a light source optically coupled with the light guide is injected, the light guide comprising a first central part made of a transparent material in which light extractors are patterned, by means of which light extractors the light produced by the light source is extracted from the light guide, characterised in that the light guide comprises a second peripheral part made of a light-absorbing material and surrounding the central part, the peripheral part being rigidly connected to the central part by an adhesive tape or by an adhesive seal, the peripheral part locally having a gap in which the light source is arranged, the peripheral part comprising one or more holes for mounting the light guide on a support part and at least one pin for fastening a printed circuit sheet used to support the light source.
A composition comprising, as an active ingredient, one or more species of Lactobacillus, one or more species of Bifidobacterium and a Streptococcus or Leuconostoc species, in a capsule, tablet, dry powder, food or beverage, for use in a method for preventing or ameliorating obesity or an obesity-related condition.
An assembly-ready joint for an aircraft assembly comprising: a first joint part comprising a spigot;a second joint part comprising a housing, a sleeve with a spigot-receiving bore extending through the sleeve, wherein the second joint part further comprises a floating socket in an interior of the housing and the floating socket defines the sleeve having the spigot-receiving bore; wherein the second joint part is arranged to receive the spigot in the floating socket, such that the spigot is inserted into the spigot-receiving bore to align the spigot with the sleeve; and wherein the second joint part is arranged to receive a curable medium in the interior of the housing to contact between the housing and the floating socket; characterised in that the second joint part comprises an opening in the housing through which the spigot is arranged to extend to be received in the floating socket, and wherein the housing comprises an inlet to the interior through which the curable medium is arranged to be received, and wherein the inlet is an injection port in the housing. a first joint part comprising a spigot;a second joint part comprising a housing, a sleeve with a spigot-receiving bore extending through the sleeve, wherein the second joint part further comprises a floating socket in an interior of the housing and the floating socket defines the sleeve having the spigot-receiving bore; wherein the second joint part is arranged to receive the spigot in the floating socket, such that the spigot is inserted into the spigot-receiving bore to align the spigot with the sleeve; and wherein the second joint part is arranged to receive a curable medium in the interior of the housing to contact between the housing and the floating socket; characterised in that the second joint part comprises an opening in the housing through which the spigot is arranged to extend to be received in the floating socket, and wherein the housing comprises an inlet to the interior through which the curable medium is arranged to be received, and wherein the inlet is an injection port in the housing.
A Traffic Collision Avoidance System, TCAS, antenna device, the antenna device comprising: a plurality of antenna elements (104a, 104b, 304, 304a, 304b, 304c); and a beam forming network configured to receive input signals comprising a the TCAS message via two input ports (306a, 306b) and transmit the TCAS message via the two or more antenna elements, wherein a beam width of a transmit beam (106, 124) that includes the transmitted TCAS message is approximately 180 degrees in azimuth, wherein the beam width and a beam direction of the transmitted TCAS message are controlled by a phase difference and amplitude difference of the input signals received at the two input ports. a plurality of antenna elements (104a, 104b, 304, 304a, 304b, 304c); and a beam forming network configured to receive input signals comprising a the TCAS message via two input ports (306a, 306b) and transmit the TCAS message via the two or more antenna elements, wherein a beam width of a transmit beam (106, 124) that includes the transmitted TCAS message is approximately 180 degrees in azimuth, wherein the beam width and a beam direction of the transmitted TCAS message are controlled by a phase difference and amplitude difference of the input signals received at the two input ports.
Arrangement, comprising: a thermosiphon device, comprising: at least one multi-port tube including a plurality of channels, and forming both an evaporator section and a condenser section for the thermosiphon device, the multi-port tube having a bend between the condenser and evaporator sections (10, 11), the bend between the condenser and evaporator sections (10, 11) providing a vapor flow path to conduct fluid evaporated in the evaporator section to the condenser section or a liquid flow path to conduct condensed liquid from the condenser section to the evaporator section; and at least one manifold (2, 3, 4) in fluid communication with ends of the condenser and evaporator sections (10,11) opposite the bend wherein the thermosiphon device is configured for vapor flowing upwardly in the evaporator section and downwardly into the condenser section; and a panel for an enclosure, said panel defining a dividing point between portions inside of the enclosure and an environment outside of the enclosure; wherein the panel is positioned between the condenser and evaporator sections (10, 11) and the panel optionally is a door for the enclosure. a thermosiphon device, comprising: at least one multi-port tube including a plurality of channels, and forming both an evaporator section and a condenser section for the thermosiphon device, the multi-port tube having a bend between the condenser and evaporator sections (10, 11), the bend between the condenser and evaporator sections (10, 11) providing a vapor flow path to conduct fluid evaporated in the evaporator section to the condenser section or a liquid flow path to conduct condensed liquid from the condenser section to the evaporator section; and at least one manifold (2, 3, 4) in fluid communication with ends of the condenser and evaporator sections (10,11) opposite the bend wherein the thermosiphon device is configured for vapor flowing upwardly in the evaporator section and downwardly into the condenser section; and at least one multi-port tube including a plurality of channels, and forming both an evaporator section and a condenser section for the thermosiphon device, the multi-port tube having a bend between the condenser and evaporator sections (10, 11), the bend between the condenser and evaporator sections (10, 11) providing a vapor flow path to conduct fluid evaporated in the evaporator section to the condenser section or a liquid flow path to conduct condensed liquid from the condenser section to the evaporator section; and at least one manifold (2, 3, 4) in fluid communication with ends of the condenser and evaporator sections (10,11) opposite the bend wherein the thermosiphon device is configured for vapor flowing upwardly in the evaporator section and downwardly into the condenser section; and a panel for an enclosure, said panel defining a dividing point between portions inside of the enclosure and an environment outside of the enclosure; wherein the panel is positioned between the condenser and evaporator sections (10, 11) and the panel optionally is a door for the enclosure.
A disposable laser transmission tip for a laser system, the disposable laser transmission tip comprising: a tip body (701; 710; 801a-e) having a both a distal end and an opposite connection end with a channel (703; 712; 803a-e) extending through the tip body from the connection end through the distal end; a tip fiber (708; 714; 805a-e) residing within the channel, with first and second ends such that the second end terminates proximate but outside the distal end and the first end terminates proximate the connection end; and a connection structure (706: 707; 713; 804a-e) coaxially encompassing the first end of the tip fiber, said connection structure fixedly situated at least partially in the connection end; wherein the connection end of the connection structure is configured to removably attach the tip body to a handpiece (109; 201) and permanently affix the fiber to the tip body, and wherein when the connection end is attached to the handpiece, the connection structure aligns the tip fibre with a fibre of the handpiece to enable laser light to be transported from the fibre of the handpiece of the tip fibre and wherein said connection end of said connection structure and said connection end of said tip body are coaxially arranged to define a space (709; 715; 806a-806e) therebetween for receiving said handpiece therein. a tip body (701; 710; 801a-e) having a both a distal end and an opposite connection end with a channel (703; 712; 803a-e) extending through the tip body from the connection end through the distal end; a tip fiber (708; 714; 805a-e) residing within the channel, with first and second ends such that the second end terminates proximate but outside the distal end and the first end terminates proximate the connection end; and a connection structure (706: 707; 713; 804a-e) coaxially encompassing the first end of the tip fiber, said connection structure fixedly situated at least partially in the connection end; wherein the connection end of the connection structure is configured to removably attach the tip body to a handpiece (109; 201) and permanently affix the fiber to the tip body, and wherein when the connection end is attached to the handpiece, the connection structure aligns the tip fibre with a fibre of the handpiece to enable laser light to be transported from the fibre of the handpiece of the tip fibre and wherein said connection end of said connection structure and said connection end of said tip body are coaxially arranged to define a space (709; 715; 806a-806e) therebetween for receiving said handpiece therein.
Method for estimating, at an instant k, the state of health SOHE(k) of an accumulator battery installed in an item of equipment and intended to supply said item of equipment with electrical energy, the value SOHE being determined by the following relation: SOHE k = SOHE model k − α ic T ⋅ SOHE model T − SOHE algorithm T in which: - SOHE model is a model of trend over time of the state of health of the battery from a state of health at an initial instant; - SOHE algorithm is an estimator making it possible to determine the state of health of the battery at any instant, from measurements of electrical quantities relating to the operation of the battery made at said instant, the instant T being a recalibration instant, prior to the instant k; - the coefficient α ic is the index of trust assigned to the value supplied by the estimator SOHE algorithm at the recalibration instant T; the method being characterized in that the coefficient α ic is defined at the instant k by the following relation: α ic k = f dSOHE algorithm SOHE algorithm in which dSOHE algorithm corresponds to the theoretical error committed on the calculation of the SOHE algorithm given the accuracy of the measurement sensors used. - SOHE model is a model of trend over time of the state of health of the battery from a state of health at an initial instant; - SOHE algorithm is an estimator making it possible to determine the state of health of the battery at any instant, from measurements of electrical quantities relating to the operation of the battery made at said instant, the instant T being a recalibration instant, prior to the instant k; - the coefficient α ic is the index of trust assigned to the value supplied by the estimator SOHE algorithm at the recalibration instant T; the method being characterized in that the coefficient α ic is defined at the instant k by the following relation: α ic k = f dSOHE algorithm SOHE algorithm in which dSOHE algorithm corresponds to the theoretical error committed on the calculation of the SOHE algorithm given the accuracy of the measurement sensors used.
A photovoltaic cell manufacturing method comprising: depositing a first buffer layer for performing lattice relaxation on a first silicon substrate; depositing a contact layer on the first buffer layer; depositing a first photoelectric conversion cell (20, 30) on the contact layer, the first photoelectric conversion cell being formed with a compound semiconductor including a pn junction, and the first photoelectric conversion cell (20, 30) having a lattice constant that is higher than that of silicon; connecting a support substrate to the first photoelectric conversion cell to form a first layered body; and removing the first buffer layer and the first silicon substrate from the first layered body to expose the contact layer. depositing a first buffer layer for performing lattice relaxation on a first silicon substrate; depositing a contact layer on the first buffer layer; depositing a first photoelectric conversion cell (20, 30) on the contact layer, the first photoelectric conversion cell being formed with a compound semiconductor including a pn junction, and the first photoelectric conversion cell (20, 30) having a lattice constant that is higher than that of silicon; connecting a support substrate to the first photoelectric conversion cell to form a first layered body; and removing the first buffer layer and the first silicon substrate from the first layered body to expose the contact layer.
A propylene-ethylene copolymer resin composition comprising: based on 100 parts by weight of the sum of the following and, 97 to 65 parts by weight of a propylene polymer produced with a metallocene catalyst and having the following properties (A-i) to (A-iii); and 3 to 35 parts by weight of a propylene-ethylene copolymer having the following properties (B-i) to (B-ii), wherein the propylene-ethylene copolymer includes: based on 100% by weight of the sum of and, 65 to 95% by weight of a propylene polymer component having the following property (B1-i); and 5 to 35% by weight of a propylene-ethylene copolymer component having the following properties (B2-i) and (B2-ii), (A-i) the polymer has an ethylene content E within the range from 0 to 6.0 wt%; (A-ii) the polymer has a melt flow rate MFR within the range from 0.1 to 100 g/10 min; (A-iii) the polymer has a ratio Mw/Mn between a weight average molecular weight Mw and a number average molecular weight Mn as measured by GPC within the range from 2 to 4; (B-i) the copolymer has an ethylene content E within the range from 0.4 to 13 wt%; (B-ii) the copolymer has a melt flow rate MFR within the range from 0.5 to 20 g/10 min; (B1-i) the polymer component has an ethylene content E within the range from 0 to 6.0 wt%; (B2-i) the copolymer component has an ethylene content E within the range from 8 to 25 wt%; and (B2-ii) the copolymer component has a melt flow rate MFR within the range from 0.0001 to 0.5 g/10 min. (A-i) the polymer has an ethylene content E within the range from 0 to 6.0 wt%; (A-ii) the polymer has a melt flow rate MFR within the range from 0.1 to 100 g/10 min; (A-iii) the polymer has a ratio Mw/Mn between a weight average molecular weight Mw and a number average molecular weight Mn as measured by GPC within the range from 2 to 4; (B-i) the copolymer has an ethylene content E within the range from 0.4 to 13 wt%; (B-ii) the copolymer has a melt flow rate MFR within the range from 0.5 to 20 g/10 min; (B1-i) the polymer component has an ethylene content E within the range from 0 to 6.0 wt%; (B2-i) the copolymer component has an ethylene content E within the range from 8 to 25 wt%; and (B2-ii) the copolymer component has a melt flow rate MFR within the range from 0.0001 to 0.5 g/10 min. (B1-i) the polymer component has an ethylene content E within the range from 0 to 6.0 wt%; (B2-i) the copolymer component has an ethylene content E within the range from 8 to 25 wt%; and (B2-ii) the copolymer component has a melt flow rate MFR within the range from 0.0001 to 0.5 g/10 min.
An apparatus for use in the drying of substrates using a solid particulate material, said apparatus comprising: (a) housing means having mounted therein a rotatably mounted cylindrical drum; (b) access means; and (c) at least one collection means, wherein said rotatably mounted cylindrical drum additionally comprises capturing and transferring means, adapted to facilitate collection of said solid particulate material and transfer of said material to said at least one collection means, wherein said capturing and transferring means comprises one or a plurality of compartments, characterised in that said collection means is physically detachable from the apparatus. (a) housing means having mounted therein a rotatably mounted cylindrical drum; (b) access means; and (c) at least one collection means,
A hydraulic machine, whose shaft is arranged upright, i.e. with its axis being arranged in the direction of gravity, wherein the shaft is supported in a case by means of a shaft bearing, the hydraulic machine furthermore comprising a shaft seal arrangement comprising a seal ring which includes a sealing lip to be directly or indirectly brought into sealing contact with the shaft and which is supported by a seal retainer flange, the shaft seal arrangement furthermore comprising a drain channel for draining leak oil and a retention ring which is arranged within an oil flow path toward the drain channel upstream or in the area of the seal ring and via which oil is passed toward the seal ring wherein the retention ring includes a retention rib extending in the direction of the seal ring and accumulating the oil up to the area of the sealing lip.
A method of making a silicone release layer comprising: applying a composition comprising one or more polysiloxane materials on a substrate and electron beam curing the composition to crosslink the polysiloxane materials, wherein the polysiloxane material comprises a silanol terminated polysiloxane fluid having a kinematic viscosity at 25°C no greater than 50,000 centistokes, wherein the composition is substantially free of catalysts and initiators.
Thermoplastic injection moulding material, which material is electrically conductive, fire-retardant and having a high tensile strength, characterised in that the material consists of: - 45 to 85 % by weight of Polyamide 6: - 5% to 25% by weight of a conductive agent; - 5% to 25% by weight of a flame retardant; - 3% to 15% by weight of an impact modifier - 0% to 4% by weight of other additives - 45 to 85 % by weight of Polyamide 6: - 5% to 25% by weight of a conductive agent; - 5% to 25% by weight of a flame retardant; - 3% to 15% by weight of an impact modifier - 0% to 4% by weight of other additives
A package for containing a consumer product composition, the package comprising: a) a product chamber for contacting the composition; and b) a substantially non-moveable outer sleeve surrounding at least a portion of the product chamber, the outer sleeve comprising a body portion and a separate and distinct base portion; c) a dispensing mechanism comprising, an actuator in the form of a dial, a dial shaft that is affixed to the actuator, and a platform that is axially displaceable via turning the actuator; and wherein at least one of the body portion and the base portion is permanently connected to the product chamber. a) a product chamber for contacting the composition; and b) a substantially non-moveable outer sleeve surrounding at least a portion of the product chamber, the outer sleeve comprising a body portion and a separate and distinct base portion; c) a dispensing mechanism comprising, an actuator in the form of a dial, a dial shaft that is affixed to the actuator, and a platform that is axially displaceable via turning the actuator; and