A sky rail-based multimodal transportation interworking system, at least comprising an elevated pillar, a rail system, a cargo vehicle, a transfer apparatus and a processor, wherein a rail beam is provided on the elevated pillar; the cargo vehicle is movably provided on a rail beam of the rail system; the transfer apparatus is used for transferring a goods loading device from a transportation tool to the cargo vehicle and loading the goods loading device onto the cargo vehicle, or unloading the goods loading device from the cargo vehicle and conveying the goods loading device onto the transportation tool; the processor is connected to the cargo vehicle and the transfer apparatus so as to control the transfer apparatus to transfer the goods loading device, and to control the cargo vehicle to move on the rail beam after the goods loading device is secured onto the cargo vehicle; wherein, as the goods loading device needs to be transferred, the transfer apparatus transfers the goods loading device from the transportation tool to the cargo vehicle and loads the goods loading device onto the cargo vehicle, and the processor controls the cargo vehicle to move on the rail beam, or the transfer apparatus unloads the goods loading device from the cargo vehicle and conveys the goods loading device onto the transportation tool; the cargo vehicle comprises a cargo vehicle bogie, a suspension device, and an integrated spreader; the bogie comprises: two train frames disposed oppositely to each other, a cross beam fixedly connected to the two train frames, at least two travelling wheels, and a travelling wheel driving device; the at least two travelling wheels are rotatably disposed on opposite surfaces of the two train frames, respectively; the travelling wheel driving device is fixed onto the train frame and is connected to the at least two travelling wheels for driving the at least two travelling wheels to rotate; one end of the suspension device is disposed on the cross beam, and the other end thereof is fixed onto the integrated spreader; the suspension-type rail beam is mounted on the elevated pillar on which two travel rails are disposed; the at least two travelling wheels of the cargo vehicle are provided on the two travel rails respectively; and the processor is connected to the travelling wheel driving device. a rail beam is provided on the elevated pillar; the cargo vehicle is movably provided on a rail beam of the rail system; the transfer apparatus is used for transferring a goods loading device from a transportation tool to the cargo vehicle and loading the goods loading device onto the cargo vehicle, or unloading the goods loading device from the cargo vehicle and conveying the goods loading device onto the transportation tool; the processor is connected to the cargo vehicle and the transfer apparatus so as to control the transfer apparatus to transfer the goods loading device, and to control the cargo vehicle to move on the rail beam after the goods loading device is secured onto the cargo vehicle; wherein, as the goods loading device needs to be transferred, the transfer apparatus transfers the goods loading device from the transportation tool to the cargo vehicle and loads the goods loading device onto the cargo vehicle, and the processor controls the cargo vehicle to move on the rail beam, or the transfer apparatus unloads the goods loading device from the cargo vehicle and conveys the goods loading device onto the transportation tool; the cargo vehicle comprises a cargo vehicle bogie, a suspension device, and an integrated spreader; the bogie comprises: two train frames disposed oppositely to each other, a cross beam fixedly connected to the two train frames, at least two travelling wheels, and a travelling wheel driving device; the at least two travelling wheels are rotatably disposed on opposite surfaces of the two train frames, respectively; the travelling wheel driving device is fixed onto the train frame and is connected to the at least two travelling wheels for driving the at least two travelling wheels to rotate; one end of the suspension device is disposed on the cross beam, and the other end thereof is fixed onto the integrated spreader; the suspension-type rail beam is mounted on the elevated pillar on which two travel rails are disposed; the at least two travelling wheels of the cargo vehicle are provided on the two travel rails respectively; and the processor is connected to the travelling wheel driving device.