A column-coupling apparatus for coupling a liquid chromatography column comprising a first end having a first column end fitting and a second end having a second column end fitting to a first tubing and to a second tubing, the apparatus comprising: a base or housing (108, 308); a first and a second tubing coupling apparatus affixed to the base or housing (108, 308), each tubing coupling apparatus for coupling one of the first and second column end fittings to one of the first and second tubings, each tubing coupling apparatus comprising: at least one body member (112, 114, 303) comprising at least one chamber; a first spring (118a, 318a) within the at least one chamber, the first spring configured so as to apply a first force to the respective tubing (6, 306) in a longitudinal direction of the respective tubing and towards the respective column end fitting (104, 304b), wherein the first force is transmitted from the first spring (118a, 318a) to the respective tubing (6, 306) either by means of a first bushing or washer and a ferrule, or by means of a collar, sleeve or flange that is affixed to or tightly engaged with the respective tube (6, 306); a second spring (118b, 318b) within the at least one chamber, the second spring configured to apply a second force to a deformable sealing member (122b, 123, 125, 323) in a direction parallel to the longitudinal direction of the respective tubing and towards the respective column end fitting, wherein the second force is transmitted from the second spring (118b, 318b) to the deformable sealing member either directly, by means of a second bushing or washer or by means of a push plate; and a pushing and latching mechanism (124, 324) configured to push the at least one body member, the first spring (118a, 318a) and the second spring (118b, 318b) towards the column in a direction parallel to the longitudinal direction of the respective tubing and in the absence of application of any twisting motion or torque to either of the respective column end fitting (104, 304b) or the respective tubing (6, 306). a base or housing (108, 308); a first and a second tubing coupling apparatus affixed to the base or housing (108, 308), each tubing coupling apparatus for coupling one of the first and second column end fittings to one of the first and second tubings, each tubing coupling apparatus comprising: at least one body member (112, 114, 303) comprising at least one chamber; a first spring (118a, 318a) within the at least one chamber, the first spring configured so as to apply a first force to the respective tubing (6, 306) in a longitudinal direction of the respective tubing and towards the respective column end fitting (104, 304b), wherein the first force is transmitted from the first spring (118a, 318a) to the respective tubing (6, 306) either by means of a first bushing or washer and a ferrule, or by means of a collar, sleeve or flange that is affixed to or tightly engaged with the respective tube (6, 306); a second spring (118b, 318b) within the at least one chamber, the second spring configured to apply a second force to a deformable sealing member (122b, 123, 125, 323) in a direction parallel to the longitudinal direction of the respective tubing and towards the respective column end fitting, wherein the second force is transmitted from the second spring (118b, 318b) to the deformable sealing member either directly, by means of a second bushing or washer or by means of a push plate; and a pushing and latching mechanism (124, 324) configured to push the at least one body member, the first spring (118a, 318a) and the second spring (118b, 318b) towards the column in a direction parallel to the longitudinal direction of the respective tubing and in the absence of application of any twisting motion or torque to either of the respective column end fitting (104, 304b) or the respective tubing (6, 306). at least one body member (112, 114, 303) comprising at least one chamber; a first spring (118a, 318a) within the at least one chamber, the first spring configured so as to apply a first force to the respective tubing (6, 306) in a longitudinal direction of the respective tubing and towards the respective column end fitting (104, 304b), wherein the first force is transmitted from the first spring (118a, 318a) to the respective tubing (6, 306) either by means of a first bushing or washer and a ferrule, or by means of a collar, sleeve or flange that is affixed to or tightly engaged with the respective tube (6, 306); a second spring (118b, 318b) within the at least one chamber, the second spring configured to apply a second force to a deformable sealing member (122b, 123, 125, 323) in a direction parallel to the longitudinal direction of the respective tubing and towards the respective column end fitting, wherein the second force is transmitted from the second spring (118b, 318b) to the deformable sealing member either directly, by means of a second bushing or washer or by means of a push plate; and a pushing and latching mechanism (124, 324) configured to push the at least one body member, the first spring (118a, 318a) and the second spring (118b, 318b) towards the column in a direction parallel to the longitudinal direction of the respective tubing and in the absence of application of any twisting motion or torque to either of the respective column end fitting (104, 304b) or the respective tubing (6, 306).