A system to separate and concentrate a component of a whole material to obtain a separated component and/or a concentrated component, comprising: an integrated separation and concentration container including a separation section and a concentration section, wherein the separation section serves for separation of the whole material; a section passage between the separation section and the concentration section; a buoy system positioned within the separation section configured to assist in a separation of the whole material and further comprising a first buoy member, a second buoy member, a third buoy member and a buoy separation volume defined between the first buoy member and the second buoy member, wherein the separated component is positioned in the buoy separation volume in use of the system; wherein the first buoy member has a first density and the second buoy member has a second density such that the buoy separation volume of the buoy system moves to a selected component density when the whole material is separated, wherein the second buoy member is interconnected with the third buoy member, wherein the third buoy member defines a buoy passage to withdraw the component (278, 278') from the buoy separation volume; and wherein the section passage is in communication with the buoy passage to allow the component (278, 278') to be moved to the concentration section; a whole material input syringe (202, 222); and at least one withdrawal syringe (210, 220); characterized in that the concentration section is associated with and separated by a wall (76, 102) from the separation section and in that the system further comprises a check valve assembly connected to the section passage; wherein the component (278, 278') is operable to be drawn through the section passage and a check valve from the separation section and pushed through the check valve assembly into the concentration section. an integrated separation and concentration container including a separation section and a concentration section, wherein the separation section serves for separation of the whole material; a section passage between the separation section and the concentration section; a buoy system positioned within the separation section configured to assist in a separation of the whole material and further comprising a first buoy member, a second buoy member, a third buoy member and a buoy separation volume defined between the first buoy member and the second buoy member, wherein the separated component is positioned in the buoy separation volume in use of the system; wherein the first buoy member has a first density and the second buoy member has a second density such that the buoy separation volume of the buoy system moves to a selected component density when the whole material is separated, wherein the second buoy member is interconnected with the third buoy member, wherein the third buoy member defines a buoy passage to withdraw the component (278, 278') from the buoy separation volume; and wherein the section passage is in communication with the buoy passage to allow the component (278, 278') to be moved to the concentration section; a whole material input syringe (202, 222); and at least one withdrawal syringe (210, 220); characterized in that the concentration section is associated with and separated by a wall (76, 102) from the separation section and in that the system further comprises a check valve assembly connected to the section passage; wherein the component (278, 278') is operable to be drawn through the section passage and a check valve from the separation section and pushed through the check valve assembly into the concentration section.