A break-open single-dose sealed package; the sealed package comprising: a first sheet of semi-rigid plastic material; a second sheet of flexible plastic material set on top of and welded to the first sheet along an annular weld, so as to define a sealed pocket which contains a dose of a product; and a pre-weakened area, which is obtained in a central area of the first sheet, so as to guide, following a folding of the sealed package, a controlled breaking of the first sheet in the pre-weakened area, in order to cause the formation of an outlet opening for the product through the first sheet; wherein the pocket, due to a central weld connecting the second sheet to the first sheet, is divided into two distinct and separate chambers, which are insulated from one another and each contain a corresponding component of the product; the single-dose sealed package is characterized in that: the annular weld that defines the pocket has a greater mechanical resistance than the central weld separating the two chambers; and the central weld dividing the pocket into the two chambers is weak, so as to be broken, without breaking the annular weld as well, by exerting a pressure on at least one of the two chambers, so as to be able to mix the two components of the product one with the other before folding the sealed package and therefore before determining a controlled breaking of the first sheet in the pre-weakened area. a first sheet of semi-rigid plastic material; a second sheet of flexible plastic material set on top of and welded to the first sheet along an annular weld, so as to define a sealed pocket which contains a dose of a product; and a pre-weakened area, which is obtained in a central area of the first sheet, so as to guide, following a folding of the sealed package, a controlled breaking of the first sheet in the pre-weakened area, in order to cause the formation of an outlet opening for the product through the first sheet; wherein the pocket, due to a central weld connecting the second sheet to the first sheet, is divided into two distinct and separate chambers, which are insulated from one another and each contain a corresponding component of the product; the single-dose sealed package is characterized in that: the annular weld that defines the pocket has a greater mechanical resistance than the central weld separating the two chambers; and the central weld dividing the pocket into the two chambers is weak, so as to be broken, without breaking the annular weld as well, by exerting a pressure on at least one of the two chambers, so as to be able to mix the two components of the product one with the other before folding the sealed package and therefore before determining a controlled breaking of the first sheet in the pre-weakened area. the annular weld that defines the pocket has a greater mechanical resistance than the central weld separating the two chambers; and the central weld dividing the pocket into the two chambers is weak, so as to be broken, without breaking the annular weld as well, by exerting a pressure on at least one of the two chambers, so as to be able to mix the two components of the product one with the other before folding the sealed package and therefore before determining a controlled breaking of the first sheet in the pre-weakened area.