A fluorinated compound of formula or pharmaceutically acceptable salts thereof, wherein (i): Y is NR 1, wherein R 1 is selected from the group consisting of hydrogen, C 1 -C 6 alkyl, cyclopropylmethyl, allyl and cyclopropyl; R 2 is selected from the group consisting of hydrogen, C 1 -C 4 alkyl, and R 5 CHOH wherein R 5 is selected from the group consisting of hydrogen, C 1 -C 3 alkyl and trifluoromethyl; R 3 is selected from the group consisting of methyl, hydrogen and CF 3 CHOH; R 4 is CHF 2; and wherein the compound of formula is a compound of formula or (ii): Y is NR 1, wherein R 1 is defined as above; R 2 is selected from the group consisting of CHF 2, CH 2 CF 3, and CF 3 CHOH; R 3 and R 4 are each selected from the group consisting of methyl and hydrogen; and wherein the compound of formula is a compound of formula or (iii): Y is NR 1 and R 1 is defined as above; R 2 is selected from the group consisting of hydrogen and C 1 -C 4 alkyl, with the proviso that when R 4 is hydrogen, R 2 is not hydrogen; R 3 is CF 3 CHOH; R 4 is selected from the group consisting of hydrogen and methyl; and wherein the compound of formula is a compound of formula (IIIC) or (iv): Y is O; R 2 is CF 3 CHOH; R 3 is selected from the group consisting of methyl and hydrogen; R 4 is selected from the group consisting of hydrogen and C 1 -C 4 alkyl; and wherein the compound of formula is a compound of formula or (v): Y is O; R 2 is hydrogen; R 3 is hydrogen; R 4 is difluoromethyl; and wherein the compound has the following chemical structure or (vi): Y is O or NR 1, wherein R 1 is defined as above; R 2 is selected from the group consisting of hydrogen, CHF 2, CH 2 CF 3, C 1 -C 6 alkyl and R 5 CHOH, wherein R 5 is selected from the group consisting of hydrogen, C 1 -C 6 alkyl and trifluoromethyl; R 3 is selected from the group consisting of methyl, hydrogen, CH 2 CF 3, CF 3 CHOH and C 1 -C 6 alkyl; and R 4 is selected from the group consisting of CHF 2, CF 3 CHOH, CH 2 CF 3, methyl, hydrogen and C 1 -C 6 alkyl; with the proviso that when R 3 is CF 3 CHOH and R 4 is hydrogen, R 2 is not hydrogen. Y is NR 1, wherein R 1 is selected from the group consisting of hydrogen, C 1 -C 6 alkyl, cyclopropylmethyl, allyl and cyclopropyl; R 2 is selected from the group consisting of hydrogen, C 1 -C 4 alkyl, and R 5 CHOH wherein R 5 is selected from the group consisting of hydrogen, C 1 -C 3 alkyl and trifluoromethyl; R 3 is selected from the group consisting of methyl, hydrogen and CF 3 CHOH; R 4 is CHF 2; and Y is NR 1, wherein R 1 is defined as above; R 2 is selected from the group consisting of CHF 2, CH 2 CF 3, and CF 3 CHOH; R 3 and R 4 are each selected from the group consisting of methyl and hydrogen; and Y is NR 1 and R 1 is defined as above; R 2 is selected from the group consisting of hydrogen and C 1 -C 4 alkyl, with the proviso that when R 4 is hydrogen, R 2 is not hydrogen; R 3 is CF 3 CHOH; R 4 is selected from the group consisting of hydrogen and methyl; and Y is O; R 2 is CF 3 CHOH; R 3 is selected from the group consisting of methyl and hydrogen; R 4 is selected from the group consisting of hydrogen and C 1 -C 4 alkyl; and Y is O; R 2 is hydrogen; R 3 is hydrogen; R 4 is difluoromethyl; and Y is O or NR 1, wherein R 1 is defined as above; R 2 is selected from the group consisting of hydrogen, CHF 2, CH 2 CF 3, C 1 -C 6 alkyl and R 5 CHOH, wherein R 5 is selected from the group consisting of hydrogen, C 1 -C 6 alkyl and trifluoromethyl; R 3 is selected from the group consisting of methyl, hydrogen, CH 2 CF 3, CF 3 CHOH and C 1 -C 6 alkyl; and R 4 is selected from the group consisting of CHF 2, CF 3 CHOH, CH 2 CF 3, methyl, hydrogen and C 1 -C 6 alkyl;