mhurhangee/ep-ind-claims huggingface dataset:
A chip for a cellular electrophysiology sensor for measuring an electrical change of a test cell, comprising: a diaphragm including a silicon layer and a silicon dioxide layer provided on an upper surface of the silicon layer, the diaphragm having a through-hole passing through the silicon layer and the silicon dioxide layer, the through-hole having an opening which opens at the silicon dioxide layer and which is adapted to capture the test cell; and a thermally-oxidized film provided on an inner wall surface of the through-hole, the thermally-oxidized film mainly containing silicon dioxide, wherein the silicon dioxide layer has a part located at the opening of the through-hole; characterized in that the thermally-oxidized film is unified with the part of the silicon dioxide layer at the opening of the through-hole by melting the thermally-oxidized film and the silicon dioxide layer, such that the silicon dioxide layer is connected to the thermally-oxidized film via a continuously-curved surface at the opening of the through-hole, the silicon dioxide layer has a thickness not smaller than 0.3 μm, and the thermally-oxidized film has a thickness ranging from 100 to 230 nm. a diaphragm including a silicon layer and a silicon dioxide layer provided on an upper surface of the silicon layer, the diaphragm having a through-hole passing through the silicon layer and the silicon dioxide layer, the through-hole having an opening which opens at the silicon dioxide layer and which is adapted to capture the test cell; and a thermally-oxidized film provided on an inner wall surface of the through-hole, the thermally-oxidized film mainly containing silicon dioxide, wherein the silicon dioxide layer has a part located at the opening of the through-hole; characterized in that the thermally-oxidized film is unified with the part of the silicon dioxide layer at the opening of the through-hole by melting the thermally-oxidized film and the silicon dioxide layer, such that the silicon dioxide layer is connected to the thermally-oxidized film via a continuously-curved surface at the opening of the through-hole, the silicon dioxide layer has a thickness not smaller than 0.3 μm, and the thermally-oxidized film has a thickness ranging from 100 to 230 nm.
High-temperature battery, which during normal operation of charging and discharging has an operating temperature in a temperature range between 150°C and 350°C, comprising a plurality of battery cells, which have respective cell housings of an electrically conductive material, and with at least one separator of an electrically insulating material, which is arranged between the cell housings of adjacent battery cells, characterized in that the at least one separator comprises a plastic and forms a self-supporting structure, which comprises at least one channel, which can be flowed through by a gaseous temperature-control medium or by a temperature-control liquid in order to remove heat from the battery cells, the at least one channel being open at least in certain regions towards the cell housing of at least one of the battery cells against which the at least one separator is lying.
An ultraviolet absorbing paint comprising an oxide precursor of at least one transition metal selected from Ti, V, Cr, Mn, Co, Ni, Cu, Zn and Ce; characterized by a binder component or a solvent which disappears under the temperature at which the oxide precursor forms a metal oxide, wherein the oxide precursor is dissolved in the binder component or the solvent, and wherein the oxide precursor of the transition metal is a metal salt, a metal acid salt, or an organic metal compound of at least one transition metal selected from Ti, V, Cr, Mn, Co, Ni, Cu, Zn and Ce.
A method of manufacturing an analyte sensor for measuring an analyte concentration in a bio-fluid, comprising: providing a core in the form of a conductive fiber; forming an annular cladding of a semiconductor material surrounding the core to form a sensor member, the semiconductor material including at least one of Periodic Table Group IV elements including silicon and germanium, Group IV compounds including silicon germanide (SiGe), and Group III and V compounds including gallium arsenide (GaAs) and indium phosphide (InP); forming a surface region of enhanced electrochemical activity on the cladding by applying localized heat via laser to a portion of a surface area of the cladding sufficient to alter a conductivity of the cladding under the surface area exposed to the localized heat to be greater than before exposure; and forming an active region over at least a portion of the surface region of enhanced electrochemical activity, the active region including one or more catalytic agents of oxidase enzymes and being adapted to be exposed to a bio-fluid sample. providing a core in the form of a conductive fiber; forming an annular cladding of a semiconductor material surrounding the core to form a sensor member, the semiconductor material including at least one of Periodic Table Group IV elements including silicon and germanium, Group IV compounds including silicon germanide (SiGe), and Group III and V compounds including gallium arsenide (GaAs) and indium phosphide (InP); forming a surface region of enhanced electrochemical activity on the cladding by applying localized heat via laser to a portion of a surface area of the cladding sufficient to alter a conductivity of the cladding under the surface area exposed to the localized heat to be greater than before exposure; and forming an active region over at least a portion of the surface region of enhanced electrochemical activity, the active region including one or more catalytic agents of oxidase enzymes and being adapted to be exposed to a bio-fluid sample.
An electrochemical cell system comprising: at least one fuel cell layer comprising at least one fuel cell having a first side and a second side; a first fluid manifold fluidly coupled to the at least one fuel cell layer to distribute a fuel to the first side of the at least one fuel cell; a second fluid manifold fluidly connecting to the first fluid manifold and to an outlet fluidly connected to a fuel storage containing said fuel, wherein the second fluid manifold is substantially flat and comprises a plurality of layers, including at least one conduit layer positioned between an upper barrier layer and a lower barrier layer, wherein the barrier layers are substantially impermeable to said fuel, and the at least one conduit layer comprises at least one conduit extending through the at least one conduit layer, wherein the first and second manifolds are arranged such that said fuel flows from the fuel storage through the second fluid manifold through the first fluid manifold and to the at least one fuel cell layer during use, wherein the barrier layers are in fluid communication with said at least one conduit in the conduit layer to form an inlet port and an outlet port, wherein the outlet port of the second fluid manifold is fluidly connected to the first fluid manifold, and the inlet port of the second fluid manifold is fluidly connected to said outlet fluidly connected to the fuel storage, wherein a portion of the barrier layer proximate the inlet port of the second fluid manifold is attached as a substantially planar interface to said outlet fluidly connected to the fuel storage. at least one fuel cell layer comprising at least one fuel cell having a first side and a second side; a first fluid manifold fluidly coupled to the at least one fuel cell layer to distribute a fuel to the first side of the at least one fuel cell; a second fluid manifold fluidly connecting to the first fluid manifold and to an outlet fluidly connected to a fuel storage containing said fuel, wherein the second fluid manifold is substantially flat and comprises a plurality of layers, including at least one conduit layer positioned between an upper barrier layer and a lower barrier layer, wherein the barrier layers are substantially impermeable to said fuel, and the at least one conduit layer comprises at least one conduit extending through the at least one conduit layer, wherein the first and second manifolds are arranged such that said fuel flows from the fuel storage through the second fluid manifold through the first fluid manifold and to the at least one fuel cell layer during use, wherein the barrier layers are in fluid communication with said at least one conduit in the conduit layer to form an inlet port and an outlet port, wherein the outlet port of the second fluid manifold is fluidly connected to the first fluid manifold, and the inlet port of the second fluid manifold is fluidly connected to said outlet fluidly connected to the fuel storage, wherein a portion of the barrier layer proximate the inlet port of the second fluid manifold is attached as a substantially planar interface to said outlet fluidly connected to the fuel storage.
A cosmetic, comprising: a liquid water-in-oil emulsified cosmetic including: an ultraviolet light absorber in an amount of 1 to 10 mass%, a ultraviolet light scattering agent and a pigment grade titanium oxide in an amount of 10 to 25 mass% and a silicone surfactant, wherein the silicone surfactant at least includes bis-butyl dimethicone polyglyceryl-3; and an impregnated body impregnated with the liquid cosmetic, the liquid cosmetic being configured to be taken from the impregnated body with a finger or an applicator for being applied to the skin. a liquid water-in-oil emulsified cosmetic including: an ultraviolet light absorber in an amount of 1 to 10 mass%, a ultraviolet light scattering agent and a pigment grade titanium oxide in an amount of 10 to 25 mass% and a silicone surfactant, wherein the silicone surfactant at least includes bis-butyl dimethicone polyglyceryl-3; and an ultraviolet light absorber in an amount of 1 to 10 mass%, a ultraviolet light scattering agent and a pigment grade titanium oxide in an amount of 10 to 25 mass% and a silicone surfactant, wherein the silicone surfactant at least includes bis-butyl dimethicone polyglyceryl-3; and an impregnated body impregnated with the liquid cosmetic, the liquid cosmetic being configured to be taken from the impregnated body with a finger or an applicator for being applied to the skin.
A compound of formula I': or a pharmaceutically acceptable salt thereof, wherein: R 1 is hydrogen, -CN, -OR, or C 1-6 aliphatic optionally substituted with 1-4 groups selected from fluorine, -CN, or OR; R 2 is hydrogen or C 1-10 aliphatic optionally substituted with 1-5 groups selected from fluorine, - CN, or -OR; Ring A is wherein Ring A is optionally substituted with 1-4 groups selected from fluorine, -CN, -OR, or C 1-6 aliphatic optionally substituted with 1-3 fluorine atoms; each R 3 is independently halogen, -CN, -R, or -OR; X is C or N; n is 0-3; and each R is independently hydrogen or C 1-6 aliphatic optionally substituted with -OH or with 1-3 fluorine atoms. R 1 is hydrogen, -CN, -OR, or C 1-6 aliphatic optionally substituted with 1-4 groups selected from fluorine, -CN, or OR; R 2 is hydrogen or C 1-10 aliphatic optionally substituted with 1-5 groups selected from fluorine, - CN, or -OR; Ring A is wherein Ring A is optionally substituted with 1-4 groups selected from fluorine, -CN, -OR, or C 1-6 aliphatic optionally substituted with 1-3 fluorine atoms; each R 3 is independently halogen, -CN, -R, or -OR; X is C or N; n is 0-3; and each R is independently hydrogen or C 1-6 aliphatic optionally substituted with -OH or with 1-3 fluorine atoms.
User equipment, comprising: a transmission and reception unit configured to communicate with a master base station and a secondary base station simultaneously in dual connectivity; an Radio Link Control, RLC, layer processing unit configured to have an RLC layer for the master base station (m-RLC) and an RLC layer for the secondary base station (s-RLC); and a Packet Data Convergence Protocol, PDCP, layer processing unit configured to have a PDCP layer transmitting and receiving data to/from the RLC layer for the master base station (m-RLC) and the RLC layer for the secondary base station (s-RLC), wherein when a transmission direction of uplink data packets is changed from the secondary base station to the master base station in a split bearer configured for the master base station and the secondary base station, the RLC layer processing unit performs re-establishment on the RLC layer for the master base station and the RLC layer for the secondary base station, and the PDCP layer processing unit performs re-establishment on the PDCP layer, to stop transmitting uplink data packets distributed before changing the transmission direction and transmit untransmitted uplink data packets to the master base station. a transmission and reception unit configured to communicate with a master base station and a secondary base station simultaneously in dual connectivity; an Radio Link Control, RLC, layer processing unit configured to have an RLC layer for the master base station (m-RLC) and an RLC layer for the secondary base station (s-RLC); and a Packet Data Convergence Protocol, PDCP, layer processing unit configured to have a PDCP layer transmitting and receiving data to/from the RLC layer for the master base station (m-RLC) and the RLC layer for the secondary base station (s-RLC), wherein when a transmission direction of uplink data packets is changed from the secondary base station to the master base station in a split bearer configured for the master base station and the secondary base station, the RLC layer processing unit performs re-establishment on the RLC layer for the master base station and the RLC layer for the secondary base station, and the PDCP layer processing unit performs re-establishment on the PDCP layer, to stop transmitting uplink data packets distributed before changing the transmission direction and transmit untransmitted uplink data packets to the master base station.
Electric bicycle with a bicycle frame, an energy store which is replaceably mounted at the bicycle frame and which can be secured by means of a lock, and a fall-out prevention device, wherein the energy store is held at the bicycle frame with the fall-out prevention device when the lock is unlocked, characterized in that the fall-out prevention device is designed as at least a force-locked snap connection in such a way that the holding force of the locking connection has to be overcome in order to remove the energy store. a bicycle frame, an energy store which is replaceably mounted at the bicycle frame and which can be secured by means of a lock, and a fall-out prevention device, wherein the energy store is held at the bicycle frame with the fall-out prevention device when the lock is unlocked, characterized in that the fall-out prevention device is designed as at least a force-locked snap connection in such a way that the holding force of the locking connection has to be overcome in order to remove the energy store.
A method for monitoring the dimensional and/or form stability of an object, which is or is to be provided with at least one reference mark, wherein the position of the reference mark is determined or measured and compared with a desired position, characterised in that the object is produced from a semi-finished product comprising fibrous material by cutting to size the semi-finished product and forming the cut-to size semi-finished product into a preform, which forms a reinforcement structure for a fibre-reinforced plastics material component to be produced, wherein the reference mark is applied to or on the semi-finished product during or after the forming of the semi-finished product into a preform.
A method of creating a biomarker profile, the method comprising the steps of: removing a sample of biofluid from a sample collection apparatus, wherein the sample is from a subject and is stored on the sample collection apparatus, the sample collection apparatus comprises cellulose paper on which the biofluid is placed to dry, and the cellulose paper has not been treated with any chemical stabilizers of nucleic acids; extracting nucleic acids from the sample; sequencing the extracted nucleic acids to generate sequence data; and analyzing the sequence data using a two-step analytical methodology to create the biomarker profile; wherein the nucleic acids are RNA, and optionally wherein the RNA is extracellular RNA; the two-step analytical methodology comprises: a) determining i) and ii) as: i) the coefficient of variance for an RNA transcript in the sample; and ii) the coefficient of variance of the RNA transcript in a reference sample; and b) removing the RNA transcript from the biomarker profile if i) is greater than ii); and the coefficient of variance for the RNA transcript in the sample and the coefficient of variance for the RNA transcript in the reference sample are determined with technical replicates that are biologically identical. removing a sample of biofluid from a sample collection apparatus, wherein the sample is from a subject and is stored on the sample collection apparatus, the sample collection apparatus comprises cellulose paper on which the biofluid is placed to dry, and the cellulose paper has not been treated with any chemical stabilizers of nucleic acids; extracting nucleic acids from the sample; sequencing the extracted nucleic acids to generate sequence data; and analyzing the sequence data using a two-step analytical methodology to create the biomarker profile; wherein the nucleic acids are RNA, and optionally wherein the RNA is extracellular RNA; the two-step analytical methodology comprises: a) determining i) and ii) as: i) the coefficient of variance for an RNA transcript in the sample; and ii) the coefficient of variance of the RNA transcript in a reference sample; and b) removing the RNA transcript from the biomarker profile if i) is greater than ii); and a) determining i) and ii) as: i) the coefficient of variance for an RNA transcript in the sample; and ii) the coefficient of variance of the RNA transcript in a reference sample; and i) the coefficient of variance for an RNA transcript in the sample; and ii) the coefficient of variance of the RNA transcript in a reference sample; and b) removing the RNA transcript from the biomarker profile if i) is greater than ii); and the coefficient of variance for the RNA transcript in the sample and the coefficient of variance for the RNA transcript in the reference sample are determined with technical replicates that are biologically identical.
A vitrectomy apparatus, comprising: a pressure source; a cut valve (316; 503) connected to the pressure source, the cut valve configured to be turned on and off to provide pressure to selectively extend and retract a vitrectomy cutting device; a sensor (315; 506) configured to sense the pressure provided from the cut valve; and a controller configured to control operation of the cut valve based on the pressure sensed by the sensor; wherein the controller is configured to monitor an amount of dwell time the vitrectomy cutting device remains open and monitor aspiration rate, and control the amount of material processed by the vitrectomy cutting device based on amount of dwell time and aspiration rate. a pressure source; a cut valve (316; 503) connected to the pressure source, the cut valve configured to be turned on and off to provide pressure to selectively extend and retract a vitrectomy cutting device; a sensor (315; 506) configured to sense the pressure provided from the cut valve; and a controller configured to control operation of the cut valve based on the pressure sensed by the sensor; wherein the controller is configured to monitor an amount of dwell time the vitrectomy cutting device remains open and monitor aspiration rate, and control the amount of material processed by the vitrectomy cutting device based on amount of dwell time and aspiration rate.
Fastening device for a cable, in particular for an electrical cable in a motor vehicle, having a grommet which can be clamped in a holder, surrounds the cable at least partially in the axial direction and is composed of elastically deformable material which is detachably fastened in a receiving opening in the holder by means of a contour, wherein the grommet has at least one guide part for installing the grommet in the receiving opening in the correct position and also has means (14, 22) for increasing the flexibility at least of the guide part, characterized in that the guide part is equipped with a wedge-shaped section, with an angle, which is designed to interact with a correspondingly wedge-shaped installation opening of the holder and in that at least one recess which is oriented perpendicular to an installation direction is provided as means for increasing the flexibility and/or in that, as means for increasing the flexibility, the grommet is designed such that at least one cavity is formed between the grommet and the cable, said cavity allowing the grommet to move relative to the cable.
An insulating component for inclusion in a down hole drill string comprising: a first part or connected group of parts, the first part or group of parts including a first connection site at or near a first end of the component for connection to a first additional component in a drill string; a second part or connected group of parts, the second part or group of parts including a second connection site at or near a second end of the component for connection to a second additional component in a drill string; a first right-hand threaded connection located between the first connection site and the second connection site; and a second left-hand threaded connection (12, 25) located between the first connection site and the second connection site, wherein the first part or group of parts is electrically insulated from the second part or group of parts through insulating material (20, 21, 22) provided between the first part or group of parts and the second part or group of parts, so that the first and second connection sites (4, 6) are electrically insulated from one another. a first part or connected group of parts, the first part or group of parts including a first connection site at or near a first end of the component for connection to a first additional component in a drill string; a second part or connected group of parts, the second part or group of parts including a second connection site at or near a second end of the component for connection to a second additional component in a drill string; a first right-hand threaded connection located between the first connection site and the second connection site; and a second left-hand threaded connection (12, 25) located between the first connection site and the second connection site, wherein the first part or group of parts is electrically insulated from the second part or group of parts through insulating material (20, 21, 22) provided between the first part or group of parts and the second part or group of parts, so that the first and second connection sites (4, 6) are electrically insulated from one another.