Method of purifying crude 4-hydroxyacetophenone, comprising or consisting of the following steps: (a) Providing crude 4-hydroxyacetophenone, (b) mixing the crude 4-hydroxyacetophenone of step (a) with one or a mixture of two or more solvent(s), (c) optionally, heating the mixture obtained in step (b) to dissolve the 4-hydroxyacetophenone, (d) optionally, adding an adsorbent, preferably activated carbon, to the mixture obtained in step (b) or step (c), if present, (e) optionally, cooling the mixture obtained in step (b), step (c) or step (d), if present, to a temperature above the crystallization temperature of 4-hydroxyacetophenone, (f) if step (d) is present, removing the adsorbent from the mixture of step (d) or step (e), if present, preferably by filtration, (g) cooling of the mixture obtained in step (b) or step (c), if present, or further cooling of the mixture obtained in step (e), if step (d) is not present, or step (f), if present, to a temperature below the crystallization temperature of 4-hydroxyacetophenone to induce crystallization of 4-hydroxyacetophenone, (h) collecting the crystallized 4-hydroxyacetophenone obtained in step (g), optionally, carrying out the additional steps (i) to (k) once or several times: (i) dissolving the crystallized 4-hydroxyacetophenone obtained in step (h) or a previous step (k), respectively, in one or a mixture of two or more solvent(s), optionally under heating, (j) cooling of the solution of step (i) to a temperature below the crystallization temperature of 4-hydroxyacetophenone to induce crystallization of 4-hydroxyacetophenone, (k) collecting the crystallized 4-hydroxyacetophenone obtained in step (j), optionally, drying of the crystallized 4-hydroxyacetophenone obtained in step (h) or step (k), preferably until the total amount of the residual solvent(s) in the 4-hydroxyacetophenone is less than 10000 ppm, preferably 5000 ppm, preferably less than 2500 ppm, more preferably less than 1000 ppm, wherein the one solvent used in steps (b) and (i), if present, is independently selected from the group consisting of diethyl carbonate and dimethyl carbonate or the two or more solvents of the mixture of two or more solvents used in steps (b) and (i), if present, are independently selected from the group consisting of ethanol, water, cyclohexane, ethyl acetate, diethyl carbonate and dimethyl carbonate. (a) Providing crude 4-hydroxyacetophenone, (b) mixing the crude 4-hydroxyacetophenone of step (a) with one or a mixture of two or more solvent(s), (c) optionally, heating the mixture obtained in step (b) to dissolve the 4-hydroxyacetophenone, (d) optionally, adding an adsorbent, preferably activated carbon, to the mixture obtained in step (b) or step (c), if present, (e) optionally, cooling the mixture obtained in step (b), step (c) or step (d), if present, to a temperature above the crystallization temperature of 4-hydroxyacetophenone, (f) if step (d) is present, removing the adsorbent from the mixture of step (d) or step (e), if present, preferably by filtration, (g) cooling of the mixture obtained in step (b) or step (c), if present, or further cooling of the mixture obtained in step (e), if step (d) is not present, or step (f), if present, to a temperature below the crystallization temperature of 4-hydroxyacetophenone to induce crystallization of 4-hydroxyacetophenone, (h) collecting the crystallized 4-hydroxyacetophenone obtained in step (g), optionally, carrying out the additional steps (i) to (k) once or several times: (i) dissolving the crystallized 4-hydroxyacetophenone obtained in step (h) or a previous step (k), respectively, in one or a mixture of two or more solvent(s), optionally under heating, (j) cooling of the solution of step (i) to a temperature below the crystallization temperature of 4-hydroxyacetophenone to induce crystallization of 4-hydroxyacetophenone, (k) collecting the crystallized 4-hydroxyacetophenone obtained in step (j), (i) dissolving the crystallized 4-hydroxyacetophenone obtained in step (h) or a previous step (k), respectively, in one or a mixture of two or more solvent(s), optionally under heating, (j) cooling of the solution of step (i) to a temperature below the crystallization temperature of 4-hydroxyacetophenone to induce crystallization of 4-hydroxyacetophenone, (k) collecting the crystallized 4-hydroxyacetophenone obtained in step (j), optionally, drying of the crystallized 4-hydroxyacetophenone obtained in step (h) or step (k), preferably until the total amount of the residual solvent(s) in the 4-hydroxyacetophenone is less than 10000 ppm, preferably 5000 ppm, preferably less than 2500 ppm, more preferably less than 1000 ppm,