mhurhangee/ep-ind-claims huggingface dataset:
A holder with a bottle, having a frame, comprising: two support platforms; vertical rods installed between said two support platforms within which the bottle for liquid is housed; the bottle having a neck; the bottle being attached to the frame through said support platforms; the bottle being made in a form of two connecting vessels (13, 14) connected to each other by their peaks; and the frame being fixed on an axis of the holder with swing joints thus providing rotation of the bottle about the axis of the holder, characterized in that the bottle is made with two necks one of which is in a lower part and another is in an upper part of the bottle; additional opening/closing external elements are located on the support platforms providing opening/closing of the two necks; two tubes are positioned inside the bottle at a place where the vessels (13, 14) meet, wherein a first tube with its larger end goes into a upper vessel, and a second tube with its larger end goes into a lower vessel, providing thereby an air pressure to a pouring liquid; the tubes are fixed at the place where the vessels meet in such a way that the liquid penetrates between the tubes; the holder has a support stand; the swing joints of the holder with the frame are adapted to fix the frame with the bottle in a desired position relative to the axis of the holder. two support platforms; vertical rods installed between said two support platforms within which the bottle for liquid is housed; the bottle having a neck; the bottle being attached to the frame through said support platforms; the bottle being made in a form of two connecting vessels (13, 14) connected to each other by their peaks; and the frame being fixed on an axis of the holder with swing joints thus providing rotation of the bottle about the axis of the holder, characterized in that the bottle is made with two necks one of which is in a lower part and another is in an upper part of the bottle; additional opening/closing external elements are located on the support platforms providing opening/closing of the two necks; two tubes are positioned inside the bottle at a place where the vessels (13, 14) meet, wherein a first tube with its larger end goes into a upper vessel, and a second tube with its larger end goes into a lower vessel, providing thereby an air pressure to a pouring liquid; the tubes are fixed at the place where the vessels meet in such a way that the liquid penetrates between the tubes; the holder has a support stand; the swing joints of the holder with the frame are adapted to fix the frame with the bottle in a desired position relative to the axis of the holder.
A wound dressing comprising a) a wound contacting layer; b) a reagent layer comprising one or more testing regions, wherein the reagent layer is in fluid communication with the wound contacting layer; and c) an outer layer that overlays the reagent layer, wherein each of the one or more testing regions comprises a reagent pad and one or more reagents selected from enzyme-reactive indicators that are protein-indicator conjugates having the structure of Formula: A-B Formula wherein: A is an anchor region or moiety that attaches an enzyme-reactive region to the reagent pad; and B is the enzyme-reactive region. a) a wound contacting layer; b) a reagent layer comprising one or more testing regions, wherein the reagent layer is in fluid communication with the wound contacting layer; and c) an outer layer that overlays the reagent layer, A is an anchor region or moiety that attaches an enzyme-reactive region to the reagent pad; and B is the enzyme-reactive region.
A method for constructing an Fv library comprising individually separated Fvs based on a combination of proteins, the method comprising the steps of: (a) separately expressing a fusion protein with a selected protein sequence in a cell, wherein the fusion protein has the sequence structure "target-LPETG-linker-Sortase A-His tag", wherein target stands for a heavy-chain variable region (V H) domain protein or a light-chain variable region (V L) domain protein; and separately purifying the VL and VH domains containing fusion protein with the His-tag, wherein the fusion protein containing the VL domain and the fusion protein containing the VH domain both comprise a coiled coil domain or have a cysteine introduced into the respective V H and V L domain protein and wherein the His-tag is removed in the course of the purification by induction of Sortase A cleavage while the coiled coil domain is retained; (b) individually pairing the fusion protein containing the V H domain and the fusion protein containing the V L domain, prepared in step (a), outside the cell, wherein the pairing is achieved by pairing by disulfide bonds between cysteines introduced in the VL and the VH domain containing proteins, pairing by coiled-coil from the fusion between coiled-coil domains, or combinations thereof; (c) storing assembled Fvs of the paired VH domain containing fusion proteins and VL domain containing fusion proteins of step (b) in individual compartments given identification numbers. (a) separately expressing a fusion protein with a selected protein sequence in a cell, wherein the fusion protein has the sequence structure "target-LPETG-linker-Sortase A-His tag", wherein target stands for a heavy-chain variable region (V H) domain protein or a light-chain variable region (V L) domain protein; and separately purifying the VL and VH domains containing fusion protein with the His-tag, wherein the fusion protein containing the VL domain and the fusion protein containing the VH domain both comprise a coiled coil domain or have a cysteine introduced into the respective V H and V L domain protein and wherein the His-tag is removed in the course of the purification by induction of Sortase A cleavage while the coiled coil domain is retained; (b) individually pairing the fusion protein containing the V H domain and the fusion protein containing the V L domain, prepared in step (a), outside the cell, wherein the pairing is achieved by pairing by disulfide bonds between cysteines introduced in the VL and the VH domain containing proteins, pairing by coiled-coil from the fusion between coiled-coil domains, or combinations thereof; (c) storing assembled Fvs of the paired VH domain containing fusion proteins and VL domain containing fusion proteins of step (b) in individual compartments given identification numbers.
A compound according to Formula I or a pharmaceutically acceptable salt thereof wherein Y is a single carbon-carbon bond or a double carbon-carbon bond, with the proviso that when Y is a double carbon-carbon bond, R' 15 and R 16 are not present; one of the three positions A 1 -A 3 is either S or NR A, the remaining two positions A 1 -A 3 are N or CR 1, CR 2, CR 3, respectively; R A is H or methyl; R 1 -R 3 are independently H, methyl, amino or halogen; A 4 -A 7 are CR 4, CR 5, CR 6 and CR 7, respectively; A 8 -A 12 are N or CR 8, CR 9, CR 10, CR 11 and CR 12, respectively, with the proviso that no more than two of the five positions A 8 - A 12 can be simultaneously N; R 4 - R 7 are independently H, halogen, C alkoxy, C alkyl; R 8 - R 12 are independently H, halogen, C alkoxy, C alkyl, cyano, nitro, -C(=O)OR 17, hydroxyl, C cycloalkyl, benzyl, phenyl, -SF 5, bicyclo[1.1.1]pentane; or R 9 and either R 8 or R 10 are fused and form an aromatic or non-aromatic five to seven membered ringcontaining two to seven carbon atoms and zero to three hetero atoms; with all carbon atoms optionally substituted with one or more methyl, halogen or hydroxyl; R 13 is H or methyl; R 14 is NH, O or S; R' 15 is H, halogen, C alkyl, -C(=O)OR 17 or -C(=O)NR 17 R 17; R 15 is H, halogen or C alkyl; R 16 is H; and, R 17 is H, methyl or ethyl. Y is a single carbon-carbon bond or a double carbon-carbon bond, with the proviso that when Y is a double carbon-carbon bond, R' 15 and R 16 are not present; one of the three positions A 1 -A 3 is either S or NR A, the remaining two positions A 1 -A 3 are N or CR 1, CR 2, CR 3, respectively; R A is H or methyl; R 1 -R 3 are independently H, methyl, amino or halogen; A 4 -A 7 are CR 4, CR 5, CR 6 and CR 7, respectively; A 8 -A 12 are N or CR 8, CR 9, CR 10, CR 11 and CR 12, respectively, with the proviso that no more than two of the five positions A 8 - A 12 can be simultaneously N; R 4 - R 7 are independently H, halogen, C alkoxy, C alkyl; R 8 - R 12 are independently H, halogen, C alkoxy, C alkyl, cyano, nitro, -C(=O)OR 17, hydroxyl, C cycloalkyl, benzyl, phenyl, -SF 5, bicyclo[1.1.1]pentane; or R 9 and either R 8 or R 10 are fused and form an aromatic or non-aromatic five to seven membered ringcontaining two to seven carbon atoms and zero to three hetero atoms; with all carbon atoms optionally substituted with one or more methyl, halogen or hydroxyl; R 13 is H or methyl; R 14 is NH, O or S; R' 15 is H, halogen, C alkyl, -C(=O)OR 17 or -C(=O)NR 17 R 17; R 15 is H, halogen or C alkyl; R 16 is H; and, R 17 is H, methyl or ethyl.
A method of processing graphics data using a graphics processing unit that includes a texture pipe, the texture pipe including one or more hardware units separate from shader processors in the graphics processing unit, configured to operate on texture data, the method comprising: receiving, by the texture pipe, texture data that comprises first texture data and second texture data said texture data comprising one or more blocks of texels; performing, by the texture pipe, a block-based operation on the texture data, including performing a swizzling operation on the texture data to pair off one or more blocks of texels in the first texture data with the corresponding ones in the second texture data, and convolving texels in the first texture data with convolution weights in the second texture data; processing graphics data with shader processors of the graphics processing unit concurrently with the texture pipe performing the block-based operation; and outputting, by the texture pipe, a result of performing the block-based operation on the texture data. receiving, by the texture pipe, texture data that comprises first texture data and second texture data said texture data comprising one or more blocks of texels; performing, by the texture pipe, a block-based operation on the texture data, including performing a swizzling operation on the texture data to pair off one or more blocks of texels in the first texture data with the corresponding ones in the second texture data, and convolving texels in the first texture data with convolution weights in the second texture data; processing graphics data with shader processors of the graphics processing unit concurrently with the texture pipe performing the block-based operation; and outputting, by the texture pipe, a result of performing the block-based operation on the texture data.
A method of operating a variable guide vane assembly of an aircraft engine, the variable guide vane assembly including guide vanes rotatable about respective spanwise axes and circumferentially distributed about a central axis, the method comprising: obtaining a target exit flow angle defined between a direction of a flow exiting the guide vanes and the central axis; predicting an exit flow angle (T2; T2') as a function of at least a geometric angle, the exit flow angle (T2; T2') defined between the direction of the flow (F1; F1') exiting the guide vanes and the central axis, the geometric angle defined between the guide vanes and the central axis; and when a difference between the exit flow angle (T2; T2') and the target exit flow angle is above a threshold, modulating the guide vanes to modify the geometric angle until the difference between the exit flow angle (T2; T2') and the target exit flow angle is at or below the threshold. obtaining a target exit flow angle defined between a direction of a flow exiting the guide vanes and the central axis; predicting an exit flow angle (T2; T2') as a function of at least a geometric angle, the exit flow angle (T2; T2') defined between the direction of the flow (F1; F1') exiting the guide vanes and the central axis, the geometric angle defined between the guide vanes and the central axis; and when a difference between the exit flow angle (T2; T2') and the target exit flow angle is above a threshold, modulating the guide vanes to modify the geometric angle until the difference between the exit flow angle (T2; T2') and the target exit flow angle is at or below the threshold.
An antioxidant composition comprising: (a) an isolate or extract comprising about 0.01% to about 20% mangiferin; and at least one of: (b) ferulic acid; (c) Vitamin C; (d) baicalin and ferulic acid; and (e) ferulic acid and Vitamin C, wherein said isolate or extract comprising mangiferin, and one or more of ferulic acid, Vitamin C, baicalin and ferulic acid, and ferulic acid and Vitamin C are present in amounts sufficient to produce synergistic antioxidant activity. (a) an isolate or extract comprising about 0.01% to about 20% mangiferin; and at least one of: (b) ferulic acid; (c) Vitamin C; (d) baicalin and ferulic acid; and (e) ferulic acid and Vitamin C,
A fastening device for curtain wall units, comprising: a first clamping plate; a second clamping plate fixed to the first clamping plate and spaced apart from the first clamping plate; a first support plate (7, 27, 37, 47) positioned between the first clamping plate and the second clamping plate; and characterised in that a second support plate (8, 28, 38, 48) is hinged to the first support plate (7, 27, 37, 47) and configured to support the curtain wall units. a first clamping plate; a second clamping plate fixed to the first clamping plate and spaced apart from the first clamping plate; a first support plate (7, 27, 37, 47) positioned between the first clamping plate and the second clamping plate; and characterised in that a second support plate (8, 28, 38, 48) is hinged to the first support plate (7, 27, 37, 47) and configured to support the curtain wall units.
A coupling structure configured to be applied in a shaving device, comprising: a first coupling component; and a second coupling component; characterized in that: wherein at least one of the first coupling component and the second coupling component is provided with a connection shaft, and another of the first coupling component and the second coupling component is provided with a connection cavity, a shape of the connection shaft is adapted to that of the connection cavity and is able to connect to or separate from the connection cavity; the connection shaft is provided with at least two protrusions extended along a radial direction, and the connection cavity is provided with lacking latches corresponding to positions of each of the protrusions and capable of sliding along a radial direction, and a front end of the lacking latches are able to protrude into the connection cavity, each of the lacking latches is provided with an elastic member configured for forcing the lacking latch to slide toward the connection cavity, and the protrusion forces the corresponding lacking latch to radially slide until it is engaged with the lacking latch. a first coupling component; and a second coupling component; characterized in that: wherein at least one of the first coupling component and the second coupling component is provided with a connection shaft, and another of the first coupling component and the second coupling component is provided with a connection cavity, a shape of the connection shaft is adapted to that of the connection cavity and is able to connect to or separate from the connection cavity; the connection shaft is provided with at least two protrusions extended along a radial direction, and the connection cavity is provided with lacking latches corresponding to positions of each of the protrusions and capable of sliding along a radial direction, and a front end of the lacking latches are able to protrude into the connection cavity, each of the lacking latches is provided with an elastic member configured for forcing the lacking latch to slide toward the connection cavity, and the protrusion forces the corresponding lacking latch to radially slide until it is engaged with the lacking latch.
An impact attenuator for vehicles adapted to be disposed in safety barriers along roads or railways, comprising an energy absorbing device for decelerating collision forces from such vehicles, a beam and a collision catcher, which is connected to the beam and displaceable along its outer side such that at a possible collision of a vehicle with the collision catcher, the same is decelerated by the energy absorbing device, characterized in that the impact attenuator also comprises a metallic, elongated draw element, wherein the energy absorbing device comprises a housing and at least two pins arranged in parallel to each other in the housing, wherein the elongated draw element is positioned within said housing such that it extends between and in contact with the pins, the pins and the elongated draw element being positioned such that at mutual moving of the elongated draw element and the housing in relation to each other, a change of direction appears on the elongated draw element when passing by each pin such that said mutual movement is decelerated due to deformation of the elongated draw element at passage of each pin, wherein the pins and the elongated draw element are positioned such that the elongated draw element obtains a change of direction of at least 90° when passing the at least two pins, respectively, wherein one of the energy absorbing device or the elongated draw element is connected to the collision catcher and displaceable together with it, while the other of these is fixedly connected to the ground or a fixed structure such that at a possible collision of a vehicle with the collision catcher, this is decelerated due to the mutual movement between the energy absorbing device and the elongated draw element.
A composite body, comprising: a substrate containing Cr; and a first composite oxide layer disposed on at least a part of a surface of the substrate, the first composite oxide layer having a spinel type crystal structure, a first largest content and a second largest content among constituent elements excluding oxygen of the first composite oxide layer being Zn and Al in random order, characterized by a zinc oxide layer disposed on the surface of the first composite oxide layer. a substrate containing Cr; and a first composite oxide layer disposed on at least a part of a surface of the substrate, the first composite oxide layer having a spinel type crystal structure, a first largest content and a second largest content among constituent elements excluding oxygen of the first composite oxide layer being Zn and Al in random order, characterized by a zinc oxide layer disposed on the surface of the first composite oxide layer.
Offshore hydrocarbon production facility arrangement to be located on a body of water, comprising a floating hydrocarbon processing unit, a floating renewable electric energy source, and a hydrogen gas source, wherein the floating renewable electric energy source is configured to generate electric energy; the hydrogen gas source is configured to produce hydrogen gas using the electric energy from the floating renewable electric energy source; the floating hydrocarbon processing unit is configured with an electric power generator; the electric power generator is coupled to the hydrogen gas source and is configured for receiving produced hydrogen gas as fuel gas. wherein the floating renewable electric energy source is configured to generate electric energy; the hydrogen gas source is configured to produce hydrogen gas using the electric energy from the floating renewable electric energy source; the floating hydrocarbon processing unit is configured with an electric power generator; the electric power generator is coupled to the hydrogen gas source and is configured for receiving produced hydrogen gas as fuel gas.
A disposable wearing article having a longitudinal direction and a transverse direction being orthogonal to the longitudinal direction, comprising a chassis having a skin-facing side, a non-skin-facing side, a front waist region, a rear waist region and a crotch region extending between the front and rear waist regions, and a liquid-absorbent structure on the skin-facing side of the chassis, wherein: the chassis has an inner sheet lying on the skin-facing side and an outer sheet lying on the non-skin-facing side; the article further comprises waist elastic elements sandwiched between the inner and outer sheets (30, 31) to extend along a waist-opening periphery of the chassis in the transverse direction; the waist elastic elements are bonded to the chassis while being stretched in the transverse direction at a stretch ratio in a range of about 2.5 to about 3.0 and have fineness in a range of about 800 to about 1000dtex; and an annular waist elastic region, which has a width of 35mm from the waist opening periphery and in which the waist elastic elements are present, exhibits a tensile stress at 255% elongation in the transverse direction in a range of about 4.5 to about 6.0N/35mm and a tensile stress at 167% elongation in the transverse direction in a range of about 1.5N/35mm or higher, wherein the inner sheet is formed of an spunbond-meltblown-spunbond fibrous nonwoven fabric having a basis mass in a range of about 10 to about 25g/m 2, the outer sheet is formed of a spunbond nonwoven fabric having a basis mass in a range of about 15 to about 25g/m 2, and the waist elastic elements are secured between the inner and outer sheets (30, 31) with hot melt adhesive applied to a partial or entire peripheral surfaces of the waist elastic elements. the chassis has an inner sheet lying on the skin-facing side and an outer sheet lying on the non-skin-facing side; the article further comprises waist elastic elements sandwiched between the inner and outer sheets (30, 31) to extend along a waist-opening periphery of the chassis in the transverse direction; the waist elastic elements are bonded to the chassis while being stretched in the transverse direction at a stretch ratio in a range of about 2.5 to about 3.0 and have fineness in a range of about 800 to about 1000dtex; and an annular waist elastic region, which has a width of 35mm from the waist opening periphery and in which the waist elastic elements are present, exhibits a tensile stress at 255% elongation in the transverse direction in a range of about 4.5 to about 6.0N/35mm and a tensile stress at 167% elongation in the transverse direction in a range of about 1.5N/35mm or higher, wherein the inner sheet is formed of an spunbond-meltblown-spunbond fibrous nonwoven fabric having a basis mass in a range of about 10 to about 25g/m 2, the outer sheet is formed of a spunbond nonwoven fabric having a basis mass in a range of about 15 to about 25g/m 2, and the waist elastic elements are secured between the inner and outer sheets (30, 31) with hot melt adhesive applied to a partial or entire peripheral surfaces of the waist elastic elements.