A compound of formula or a pharmaceutically acceptable salt thereof: wherein: A is a single or double bond; B is a single or double bond; R 1 and R 5 are independently hydrogen, hydroxyl, oxo, oximino or alkoxyimino, provided that R 1 is hydroxyl only when A is a single bond, and that R 5 is hydroxyl only when B is a single bond; R 2 and R 6 are independently linear or branched C 1 -C 8 alkyl, C 2 -C 8 alkenyl, or C 3 -C 8 cycloalkyl; R 3 and R 7 are independently hydroxyl, methoxy, oxo, hydroximino, or alkoxyimino; R 4 and R 8 are independently hydrogen, hydroxyl, C 1 -C 8 alkanoyloxy, benzoyloxy, di-C 1 -C 8 alkylamino benzoyloxy, (C 1 -C 8 alkoxy) p, C 1 -C 8 alkylthio, C 1 -C 8 alkylthioalkoxy or oleandrosyloxy; R 9 and R 10 are independently diradical groups selected from a bond, O, NR 11, -NR 11 C(=O)-, -NR 11 C(=S)-, -NR 11 C(=O)O-, -ONR 11 C(=O)-, -ONR 11 C(=O)O-, -ONR 11 C(=O)NR 11 -, -OC(=O)O-, -N(R 11)C(=O)N(R 11)-, -N(R 11)C(=S)N(R 11)-, -N(R 11)S 2 N(R 11)-, -N(R 11)S 2 -, -N(R 11)S N(R 11)-, -N(R 11)S -, -C(=NR 11)-, -C(=O)-, -C(=O)N(R 11)-, and -C(=S)N(R 11)-; R 11 is H or R 2; L is a diradical linker selected from a bond, C 1 -C 20 alkylene, C 2 -C 20 alkenylene, C 2 -C 20 alkynylene, C 3 -C 8 cycloalkylene, arylene, aryloxy arylene, heteroarylene, or any combination thereof, which may optionally contain a N, O, S, P, or Si atom; and wherein said linker may optionally be substituted with one or more groups selected from cyano, nitro, hydroxy, halogen, O, N, S, C 1 -C 6 alkyl, C 3 -C 8 cycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 thioalkyl, oxo, oximino, and alkoxyimino; m and n are independently 0, 1, or 2; and p is 1-3; wherein R 9 and R 10 may be connected to any two atoms of linker L. A is a single or double bond; B is a single or double bond; R 1 and R 5 are independently hydrogen, hydroxyl, oxo, oximino or alkoxyimino, provided that R 1 is hydroxyl only when A is a single bond, and that R 5 is hydroxyl only when B is a single bond; R 2 and R 6 are independently linear or branched C 1 -C 8 alkyl, C 2 -C 8 alkenyl, or C 3 -C 8 cycloalkyl; R 3 and R 7 are independently hydroxyl, methoxy, oxo, hydroximino, or alkoxyimino; R 4 and R 8 are independently hydrogen, hydroxyl, C 1 -C 8 alkanoyloxy, benzoyloxy, di-C 1 -C 8 alkylamino benzoyloxy, (C 1 -C 8 alkoxy) p, C 1 -C 8 alkylthio, C 1 -C 8 alkylthioalkoxy or oleandrosyloxy; R 9 and R 10 are independently diradical groups selected from a bond, O, NR 11, -NR 11 C(=O)-, -NR 11 C(=S)-, -NR 11 C(=O)O-, -ONR 11 C(=O)-, -ONR 11 C(=O)O-, -ONR 11 C(=O)NR 11 -, -OC(=O)O-, -N(R 11)C(=O)N(R 11)-, -N(R 11)C(=S)N(R 11)-, -N(R 11)S 2 N(R 11)-, -N(R 11)S 2 -, -N(R 11)S N(R 11)-, -N(R 11)S -, -C(=NR 11)-, -C(=O)-, -C(=O)N(R 11)-, and -C(=S)N(R 11)-; R 11 is H or R 2; L is a diradical linker selected from a bond, C 1 -C 20 alkylene, C 2 -C 20 alkenylene, C 2 -C 20 alkynylene, C 3 -C 8 cycloalkylene, arylene, aryloxy arylene, heteroarylene, or any combination thereof, which may optionally contain a N, O, S, P, or Si atom; and wherein said linker may optionally be substituted with one or more groups selected from cyano, nitro, hydroxy, halogen, O, N, S, C 1 -C 6 alkyl, C 3 -C 8 cycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 thioalkyl, oxo, oximino, and alkoxyimino; m and n are independently 0, 1, or 2; and p is 1-3; wherein R 9 and R 10 may be connected to any two atoms of linker L.