mhurhangee/ep-ind-claims huggingface dataset:
A compound having a structure of Formula I: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein: L 1 and L 2 are each independently -O(C=O)-, -(C=O)O- or a direct bond; G 1 is -(C=O)- or a direct bond; G 2 is a direct bond; G 3 is C 2 -C 5 alkylene; R 1a and R 1b are, at each occurrence, independently either: (a) H or C 1 -C 12 alkyl; or (b) R 1a is H or C 1 -C 12 alkyl, and R 1b together with the carbon atom to which it is bound is taken together with an adjacent R 1b and the carbon atom to which it is bound to form a carbon-carbon double bond; R 2a and R 2b are, at each occurrence, independently either: (a) H or C 1 -C 12 alkyl; or (b) R 2a is H or C 1 -C 12 alkyl, and R 2b together with the carbon atom to which it is bound is taken together with an adjacent R 2b and the carbon atom to which it is bound to form a carbon-carbon double bond; R 3a and R 3b are, at each occurrence, independently either (a): H or C 1 -C 12 alkyl; or (b) R 3a is H or C 1 -C 12 alkyl, and R 3b together with the carbon atom to which it is bound is taken together with an adjacent R 3b and the carbon atom to which it is bound to form a carbon-carbon double bond; R 4a and R 4b are, at each occurrence, independently either: (a) H or C 1 -C 12 alkyl; or (b) R 4a is H or C 1 -C 12 alkyl, and R 4b together with the carbon atom to which it is bound is taken together with an adjacent R 4b and the carbon atom to which it is bound to form a carbon-carbon double bond; R 5 and R 6 are each independently H or methyl; R 7 is C 1 -C 2 alkyl; R 8 is OH; and a, b, c and d are each independently an integer from 4 to 12. L 1 and L 2 are each independently -O(C=O)-, -(C=O)O- or a direct bond; G 1 is -(C=O)- or a direct bond; G 2 is a direct bond; G 3 is C 2 -C 5 alkylene; R 1a and R 1b are, at each occurrence, independently either: (a) H or C 1 -C 12 alkyl; or (b) R 1a is H or C 1 -C 12 alkyl, and R 1b together with the carbon atom to which it is bound is taken together with an adjacent R 1b and the carbon atom to which it is bound to form a carbon-carbon double bond; R 2a and R 2b are, at each occurrence, independently either: (a) H or C 1 -C 12 alkyl; or (b) R 2a is H or C 1 -C 12 alkyl, and R 2b together with the carbon atom to which it is bound is taken together with an adjacent R 2b and the carbon atom to which it is bound to form a carbon-carbon double bond; R 3a and R 3b are, at each occurrence, independently either (a): H or C 1 -C 12 alkyl; or (b) R 3a is H or C 1 -C 12 alkyl, and R 3b together with the carbon atom to which it is bound is taken together with an adjacent R 3b and the carbon atom to which it is bound to form a carbon-carbon double bond; R 4a and R 4b are, at each occurrence, independently either: (a) H or C 1 -C 12 alkyl; or (b) R 4a is H or C 1 -C 12 alkyl, and R 4b together with the carbon atom to which it is bound is taken together with an adjacent R 4b and the carbon atom to which it is bound to form a carbon-carbon double bond; R 5 and R 6 are each independently H or methyl; R 7 is C 1 -C 2 alkyl; R 8 is OH; and a, b, c and d are each independently an integer from 4 to 12.
An isolated interface circuit for a modular energy system (2000, 3000), the isolated interface circuit comprising: a comparator (4408, 4410) comprising a first input configured to couple to a switch (4404, 4406), a second input configured to couple to a reference voltage, and an output; a duplicate comparator (4412, 4414) comprising a first input configured to couple to the switch, a second input configured to couple to the reference voltage, and an output; an expander circuit comprising at least two inputs, wherein the output of the comparator is coupled to one of the at least two inputs of the expander circuit, and wherein the output of the duplicate comparator is coupled to other of the at least two inputs of the expander circuit, the expander circuit comprising an output; an isolator circuit comprising an input and an output, wherein the input is coupled to the output of the expander circuit; and a controller coupled to the output of the isolator circuit, wherein the controller is configured to: compare the output of the comparator with the output of the duplicate comparator; and determine activation or deactivation of a surgical instrument coupled to the controller based on the comparison. a comparator (4408, 4410) comprising a first input configured to couple to a switch (4404, 4406), a second input configured to couple to a reference voltage, and an output; a duplicate comparator (4412, 4414) comprising a first input configured to couple to the switch, a second input configured to couple to the reference voltage, and an output; an expander circuit comprising at least two inputs, wherein the output of the comparator is coupled to one of the at least two inputs of the expander circuit, and wherein the output of the duplicate comparator is coupled to other of the at least two inputs of the expander circuit, the expander circuit comprising an output; an isolator circuit comprising an input and an output, wherein the input is coupled to the output of the expander circuit; and a controller coupled to the output of the isolator circuit, wherein the controller is configured to: compare the output of the comparator with the output of the duplicate comparator; and determine activation or deactivation of a surgical instrument coupled to the controller based on the comparison. compare the output of the comparator with the output of the duplicate comparator; and determine activation or deactivation of a surgical instrument coupled to the controller based on the comparison.
A motor vehicle control device having a switch-on and switch-off function for at least one electrical load to be controlled by the motor vehicle control device, comprising an electronic switching element for arrangement in a supply voltage path (12.1) of the load and a control unit for controlling the electronic switching element, wherein the control unit is designed to provide a control signal for switching the electronic switching element on the basis of at least one input signal, characterized in that the load is a steering actuating drive of the motor vehicle.
Composition for use in a mechanical dishwasher, characterized by - a base composition which displays its function essentially in the main wash cycle of the dishwasher in the form of a tablet; - two regions (10, 10') arranged in or on the tablet, of which a first region comprises at least one substance which is intended to display its function essentially in the rinse cycle of the dishwasher and a second region which comprises at least one substance which prevents lime deposits in the dishwasher and/or on the ware; and - in each case an envelope which surrounds the regions (10, 10') substantially completely and comprises at least one compound whose solubility increases as the concentration of a specific ion in the surrounding medium falls, such that the substances present in the two regions are released at least predominantly at the earliest at the beginning of the rinse cycle. - a base composition which displays its function essentially in the main wash cycle of the dishwasher in the form of a tablet; - two regions (10, 10') arranged in or on the tablet, of which a first region comprises at least one substance which is intended to display its function essentially in the rinse cycle of the dishwasher and a second region which comprises at least one substance which prevents lime deposits in the dishwasher and/or on the ware; and - in each case an envelope which surrounds the regions (10, 10') substantially completely and comprises at least one compound whose solubility increases as the concentration of a specific ion in the surrounding medium falls, such that the substances present in the two regions are released at least predominantly at the earliest at the beginning of the rinse cycle.
An operation method for a hydrogen production apparatus that is disposed in a hydrogen station and produces hydrogen gas to be supplied to a fuel cell vehicle (FCV, 200) arriving at the hydrogen station, the operation method comprising: starting up a hydrogen production apparatus up to a first operation load ratio preset for a rated operation; increasing an operation load of the hydrogen production apparatus to a second load ratio larger than the first operation load ratio at first timing associated with an arrival of the FCV; and decreasing the operation load of the hydrogen production apparatus to a third operation load ratio smaller than the second operation load ratio at second timing associated with a completion of hydrogen filling into the FCV, wherein an increase in the operation load due to the first timing with respect to a subsequent FCV arriving at the hydrogen station next to a previous FCV takes precedence over a decrease in the operation load due to the second timing with respect to the previous FCV. starting up a hydrogen production apparatus up to a first operation load ratio preset for a rated operation; increasing an operation load of the hydrogen production apparatus to a second load ratio larger than the first operation load ratio at first timing associated with an arrival of the FCV; and decreasing the operation load of the hydrogen production apparatus to a third operation load ratio smaller than the second operation load ratio at second timing associated with a completion of hydrogen filling into the FCV, wherein an increase in the operation load due to the first timing with respect to a subsequent FCV arriving at the hydrogen station next to a previous FCV takes precedence over a decrease in the operation load due to the second timing with respect to the previous FCV.
A method for controlling an operating state of a network interface in a computer system, comprising: in response to receiving a request from an application to use the network interface for a route, creating a route structure for the route; and incrementing a route reference counter in an interface data structure for the network interface; upon determining that the application is no longer using the route, setting a route expiration timer in the route structure to a predetermined expiration time; when the route expiration timer expires, deleting the route structure and decrementing the route reference counter in the interface data structure; and when decrementing the route reference counter in the interface data structure causes the route reference counter to be equal to zero, sending a signal to a configuration application to inform the application that the network interface can be idled. in response to receiving a request from an application to use the network interface for a route, creating a route structure for the route; and incrementing a route reference counter in an interface data structure for the network interface; upon determining that the application is no longer using the route, setting a route expiration timer in the route structure to a predetermined expiration time; when the route expiration timer expires, deleting the route structure and decrementing the route reference counter in the interface data structure; and when decrementing the route reference counter in the interface data structure causes the route reference counter to be equal to zero, sending a signal to a configuration application to inform the application that the network interface can be idled.
Method for installing a rule for executing an operating environment for a communication terminal in a mobile network of an operator, said environment being called operator profile, the operator profile being stored in a subscriber module (eSIM) embedded in the terminal, the method comprising the following steps implemented by the subscriber module: • obtaining a first token (tokOp1) from the operator, the first token comprising an item of information relating to the identification of the rule and a signature of the operator; • obtaining a second token (tokDM) from the operator, the second token comprising a first verification means for verifying the authenticity of the first token and a signature of a third party (DM; CM) other than the operator; • verifying the authenticity of the first token by way of the first verification means; • verifying the authenticity of the second token by way of a second verification means pre-installed in the subscriber module by the third party; • installing the rule in the subscriber module if the authenticities of the first and second tokens are verified. • obtaining a first token (tokOp1) from the operator, the first token comprising an item of information relating to the identification of the rule and a signature of the operator; • obtaining a second token (tokDM) from the operator, the second token comprising a first verification means for verifying the authenticity of the first token and a signature of a third party (DM; CM) other than the operator; • verifying the authenticity of the first token by way of the first verification means; • verifying the authenticity of the second token by way of a second verification means pre-installed in the subscriber module by the third party; • installing the rule in the subscriber module if the authenticities of the first and second tokens are verified.
A first communications device, wherein the first communications device is disposed in a first vehicle, and the first communications device comprises: a first information processing unit, wherein the first information processing unit obtains first status information of the first vehicle; determines, based on the first status information, whether a vehicle accident occurs and generates a first emergency call message when determining that the vehicle accident has occurred; and a first vehicle-to-vehicle communications unit, wherein the first vehicle-to-vehicle communications unit is coupled to the first information processing unit, and the first vehicle-to-vehicle communications unit receives the first emergency call message from the first information processing unit, characterized in that the first emergency call message comprises a first accident level; the first vehicle-to-vehicle communications unit sends the first emergency call message in a first range around the first vehicle; after sending the first emergency call message, the first information processing unit obtains second status information of the first vehicle; and when the first vehicle-to-vehicle communications unit receives, within first duration, a rescue response message in response to the first emergency call message, the first information processing unit generates, based on the second status information and the rescue response message, a second emergency call message comprising a second accident level, and sends the second emergency call message in a second range around the first vehicle. a first information processing unit, wherein the first information processing unit obtains first status information of the first vehicle; determines, based on the first status information, whether a vehicle accident occurs and generates a first emergency call message when determining that the vehicle accident has occurred; and a first vehicle-to-vehicle communications unit, wherein the first vehicle-to-vehicle communications unit is coupled to the first information processing unit, and the first vehicle-to-vehicle communications unit receives the first emergency call message from the first information processing unit, characterized in that the first emergency call message comprises a first accident level; the first vehicle-to-vehicle communications unit sends the first emergency call message in a first range around the first vehicle; after sending the first emergency call message, the first information processing unit obtains second status information of the first vehicle; and when the first vehicle-to-vehicle communications unit receives, within first duration, a rescue response message in response to the first emergency call message, the first information processing unit generates, based on the second status information and the rescue response message, a second emergency call message comprising a second accident level, and sends the second emergency call message in a second range around the first vehicle.
A glycopeptide antibiotic for use in the treatment of a bacterial infection in a subject, comprising administering to a subject having a bacterial infection a glycopeptide antibiotic via an intravenous route, wherein the glycopeptide antibiotic is oritavancin, or a pharmaceutically acceptable salt, hydrate, or solvate thereof, or a mixture thereof, wherein the effective amount of the glycopeptide antibiotic is between about 20 and 30 mg/kg body weight, and wherein the glycopeptide antibiotic provides a fraction of glycopeptide antibiotic bound to serum proteins in the subject in the range of about 50% to about 95%, and wherein the glycopeptide antibiotic is for use in a method comprising administration of said glycopeptide antibiotic once weekly, every eight days, every nine days, every ten days, bi-weekly, monthly, bi-monthly, or as a single dose.
A system, comprising: an anchor body comprising a head and a hollow chamber shaft coupled to the head, wherein the anchor body is above a valley of a metal deck; and a housing sleeve configured to support the anchor body, wherein the housing sleeve comprises one or more fasteners pre-threaded into a base of the housing sleeve, characterized in that the housing sleeve comprises an arch, arching upwards from the base in direction to the head creating a hollow space configured to adapt to a ridge of a metal deck which is secured to the base. an anchor body comprising a head and a hollow chamber shaft coupled to the head, wherein the anchor body is above a valley of a metal deck; and a housing sleeve configured to support the anchor body, wherein the housing sleeve comprises one or more fasteners pre-threaded into a base of the housing sleeve, characterized in that the housing sleeve comprises an arch, arching upwards from the base in direction to the head creating a hollow space configured to adapt to a ridge of a metal deck which is secured to the base.
A solid-state germanium-68 source material comprising: a matrix material having a three-dimensional polyhedral crystal structure, the matrix material comprising: a first tetrahedra comprising a central atom, T, and oxygen, the central atom being selected from the group consisting of silicon, aluminum, zirconium and stable germanium, the first tetrahedra having a formula TO 4; and a second tetrahedra, the second tetrahedra being a germanium-68 tetrahedra comprising germanium-68 and oxygen and having a formula 68 GeO 4, the first tetrahedra and germanium-68 tetrahedra being part of a three-dimensional polyhedral crystal structure. a first tetrahedra comprising a central atom, T, and oxygen, the central atom being selected from the group consisting of silicon, aluminum, zirconium and stable germanium, the first tetrahedra having a formula TO 4; and a second tetrahedra, the second tetrahedra being a germanium-68 tetrahedra comprising germanium-68 and oxygen and having a formula 68 GeO 4, the first tetrahedra and germanium-68 tetrahedra being part of a three-dimensional polyhedral crystal structure.
A compound of the formula or a pharmaceutically acceptable salt thereof, wherein X is O or CH 2; Y is O or CH 2; R 1 is H or -NHR 3; R 2 is R 3 is H, CH 3, C 2 H 5, CH 2 CH 2 CH 3, CH(CH 3) 2, CH 2 CHF 2, CH 2 CF 3, or CH 2 -C 3-8 cycloalkyl; R 4 is H, C 1-6 alkyl, CF 3 or CHF 2; R 5 is H, halogen, CH 3, CF 3, or CHF 2; R 6 is NH 2 or C 1-6 alkyl; Z is CH or N; and A is CH, N or C-NH 2. X is O or CH 2; Y is O or CH 2; R 1 is H or -NHR 3; R 2 is R 3 is H, CH 3, C 2 H 5, CH 2 CH 2 CH 3, CH(CH 3) 2, CH 2 CHF 2, CH 2 CF 3, or CH 2 -C 3-8 cycloalkyl; R 4 is H, C 1-6 alkyl, CF 3 or CHF 2; R 5 is H, halogen, CH 3, CF 3, or CHF 2; R 6 is NH 2 or C 1-6 alkyl; Z is CH or N; and A is CH, N or C-NH 2.
A laser bonding method of joining an inner circumferential surface of a member made of a resin material transmitting laser light with an outer circumferential surface of a pipe made of a resin material absorbing laser light, the method comprising the steps of: fixing the pipe and the member to a setting portion provided on a front side of a base; and fusing and joining the entire outer circumferential surface of the pipe with the entire inner circumferential surface of the member by applying the laser light onto a junction between the pipe and the member fixed to the setting portion while causing a light emission unit to revolve around the junction, the light emission unit being configured to emit the laser light and attached to a pulley or a gear, the pulley or the gear being provided on a back side of the base, and the light emission unit revolving around the junction as the pulley or the gear is rotated. fixing the pipe and the member to a setting portion provided on a front side of a base; and fusing and joining the entire outer circumferential surface of the pipe with the entire inner circumferential surface of the member by applying the laser light onto a junction between the pipe and the member fixed to the setting portion while causing a light emission unit to revolve around the junction, the light emission unit being configured to emit the laser light and attached to a pulley or a gear, the pulley or the gear being provided on a back side of the base, and the light emission unit revolving around the junction as the pulley or the gear is rotated.
A secondary component for connection to a dental implant having an internal bore, said secondary component comprising a head part and a base part, the head part comprising a coronal portion which in use protrudes from the dental implant, and, apical of the coronal portion, an attachment portion, the base part comprising implant connection means for connection to an implant and fastening means, wherein the attachment portion and fastening means can be directly coupled together in a rotatable manner in order to axially join the head and base parts together, while still enabling the base part to be rotated relative to the head part, the head part further comprising a through passage extending from the coronal portion to the attachment portion characterised in that the base part further comprises drive means having a non-circular cross-section capable of transmitting torque to the base part which, when the head and base parts are coupled together, is in communication with this passage. a head part and a base part, the head part comprising a coronal portion which in use protrudes from the dental implant, and, apical of the coronal portion, an attachment portion, the base part comprising implant connection means for connection to an implant and fastening means,