mhurhangee/ep-ind-claims huggingface dataset:
Sucrose phosphorylase comprising an amino acid sequence which has an identity in relation to the amino acid sequence according to SEQ ID NO:1 of at least 80%; which, in comparison with SEQ ID NO:1, comprises an amino acid mutation in position H185 and an amino acid mutation in position 1295; and which, in comparison with the sucrose phosphorylase according to SEQ ID NO:1, has (i) an increased activity with respect to the conversion of sucrose and phosphate to glucose 1-phosphate and fructose in the presence of equimolar amounts of glucose 1-phosphate and fructose; and/or (ii) a lower inhibition by fructose with respect to the conversion of sucrose and phosphate to glucose 1-phosphate and fructose in the presence of equimolar amounts of glucose 1-phosphate and fructose; and/or (iii) a higher temperature stability after incubation at 58°C for 15 min. (i) an increased activity with respect to the conversion of sucrose and phosphate to glucose 1-phosphate and fructose in the presence of equimolar amounts of glucose 1-phosphate and fructose; and/or (ii) a lower inhibition by fructose with respect to the conversion of sucrose and phosphate to glucose 1-phosphate and fructose in the presence of equimolar amounts of glucose 1-phosphate and fructose; and/or (iii) a higher temperature stability after incubation at 58°C for 15 min.
A method of solid freeform fabrication, comprising: dispensing a modeling material, a support material, and at least one additional material which is non-solidifiable and which is different from both said modeling and said support materials, wherein each of said materials is dispensed from a different dispensing head, wherein said at least one additional material cannot function as a modeling material on its own, wherein said at least one additional material and said modeling material combine after said dispensing to form a solidifiable mixture, and at least partially solidifying said modeling material, such as to form a three-dimensional object. dispensing a modeling material, a support material, and at least one additional material which is non-solidifiable and which is different from both said modeling and said support materials, wherein each of said materials is dispensed from a different dispensing head, wherein said at least one additional material cannot function as a modeling material on its own, wherein said at least one additional material and said modeling material combine after said dispensing to form a solidifiable mixture, and at least partially solidifying said modeling material, such as to form a three-dimensional object.
Combustion chamber for a turbomachine, comprising at least one annular casing delimiting an inner volume of the combustion chamber and provided with a chimney extending to the outside of the inner volume and delimiting a passage for a penetrating part through the annular casing, and a bushing mounted floating on the chimney, characterised in that it further comprises: - a main air collection chamber, open to the upstream and closed to the downstream, arranged facing a downstream portion of the chimney; and - at least one through-opening formed in the annular casing and putting into direct communication the inner volume of the combustion chamber and the main air collection chamber. - a main air collection chamber, open to the upstream and closed to the downstream, arranged facing a downstream portion of the chimney; and - at least one through-opening formed in the annular casing and putting into direct communication the inner volume of the combustion chamber and the main air collection chamber.
An aerosol provision system comprising: a liquid storage area comprising a liquid formulation; an aerosol generating area; a membrane disposed between the liquid storage area and the aerosol generating area, said membrane fluidly communicating the liquid storage area with the aerosol generating area; wherein the liquid formulation has a water content of at least 18% w/w; and wherein the aerosol generating area comprises an aerosol generating component. a liquid storage area comprising a liquid formulation; an aerosol generating area; a membrane disposed between the liquid storage area and the aerosol generating area, said membrane fluidly communicating the liquid storage area with the aerosol generating area; wherein the liquid formulation has a water content of at least 18% w/w; and wherein the aerosol generating area comprises an aerosol generating component.
Device for adjusting a voltage, with at least one electromagnetic device, comprising at least one first power coil on a first power magnet core, wherein an input voltage is applied to the first power coil, at least one second power coil on a second power magnet core, wherein the second power coil is led to a voltage output at which an output voltage is present, wherein the first and second power coils are connected by way of a conductor bridge, and at least one control coil on a control magnet core, wherein the two power magnet cores (6a, 6b) and the control magnet core are a component of a closed magnet core having three parallelly extending arms, wherein the centre arm forms the control magnet core and the outer arms form the power magnet cores (6a, 6b), wherein the power coils (10a, 10b) are so constructed that no voltage at the control coil is generated by these, wherein at least one adjusting unit connected with the control coil is provided, wherein the adjusting unit is configured so that a control current, by means of which the control magnet core is bought wholly or partly to saturation, for the control coil is generated in dependence on a target value for the output voltage, whereby adjustment of the output voltage is carried out in such a way that a mains voltage of a current mains does not exceed a permissible limit value, characterised in that the adjusting unit is a regulating unit which is designed in such a way that the output voltage is regulated to a target value, wherein the regulating unit has an interface for reading-in of the target value and a connection for reading-in of the output voltage as actual value.
Romiplostim for use in the treatment of aplastic anemia, wherein Romiplostim is administered subcutaneously once a week, and wherein Romiplostim is administered at 10 μg/kg/week for 4 weeks from the start of administration, and administered at more than 10 μg/kg/week and a maximum of 20 μg/kg/week from week 5, wherein: (i) Romiplostim is administered at 15 μg/kg/week from week 5 to week 8 and administered at a maximum of 20 μg/kg/week from week 9, and wherein the same dose is maintained for 4 weeks or more after a dose change, or (ii) Romiplostim is administered at 15 or 20 μg/kg/week from week 5, and wherein the same dose is maintained for 4 weeks or more after a dose change; and/or a dose increment of Romiplostim from week 5 is 5 μg/kg. (i) Romiplostim is administered at 15 μg/kg/week from week 5 to week 8 and administered at a maximum of 20 μg/kg/week from week 9, and wherein the same dose is maintained for 4 weeks or more after a dose change, or (ii) Romiplostim is administered at 15 or 20 μg/kg/week from week 5, and wherein the same dose is maintained for 4 weeks or more after a dose change; and/or (i) Romiplostim is administered at 15 μg/kg/week from week 5 to week 8 and administered at a maximum of 20 μg/kg/week from week 9, and wherein the same dose is maintained for 4 weeks or more after a dose change, or (ii) Romiplostim is administered at 15 or 20 μg/kg/week from week 5, and wherein the same dose is maintained for 4 weeks or more after a dose change; and/or a dose increment of Romiplostim from week 5 is 5 μg/kg.
A urine measuring device for measuring urine production of a patient carrying a urine catheter, the device comprising a self-emptying siphon chamber, which in turn comprises an inlet connectable to the catheter and an outlet for the urine whose volume is to be measured, and wherein the device further comprises a base unit having an attachment organ (137, 138, 139, 350, 351) for removably attaching the self-emptying siphon chamber to the base unit, the base unit being provided with a urine level measurement organ, capable of sensing changes in the level of urine in the self-emptying siphon chamber, and wherein the urine level measurement organ comprises two capacitance electrodes (310, 320, 140, 141) placed apart relative to each other on the base unit, such that when the self-emptying siphon chamber is attached to the base unit, the capacitance electrodes (310, 320, 140, 141) are capable of sensing a capacitance signal occurring between the two capacitance electrodes (310, 320, 140, 141), which capacitance signal changes as the level of urine in the self-emptying siphon chamber changes, and the capacitance signal therefore constitutes a measure of the produced amount of urine.
A prosthesis extending about a longitudinal axis between a proximal end and a distal end, the prosthesis comprising: an expandable tubular frame having a lumen longitudinally extending therein about a longitudinal axis, the frame including a longitudinal first region coupled to a longitudinal second region, wherein the longitudinal second region is proximal to and has a greater radial stiffness than the longitudinal first region, the longitudinal first region comprising a first annular segment and an annular flex segment adjacent to one another, the first annular segment including a proximal first annular stent member and a distal first annular stent member adjacent to one another, each of the proximal and distal first annular stent members having proximal and distal apices arranged in a peak-to-peak relationship with one another, wherein at least a portion of the distal apices and corresponding proximal apices of the respective proximal and distal first annular stent members remain uncoupled to one another, the annular flex segment including at least one second annular stent member having proximal and distal apices arranged in a peak-to-valley relationship with the proximal and distal first annular stent members, wherein a longitudinal tie bar is coupled between one of the proximal apices of the second annular stent member and one of the proximal apices of the distal first annular stent member at a coupling joint, wherein the coupling joint is located where the distal and the corresponding proximal apices of the proximal and distal first annular stent members remain uncoupled to one another. an expandable tubular frame having a lumen longitudinally extending therein about a longitudinal axis, the frame including a longitudinal first region coupled to a longitudinal second region, wherein the longitudinal second region is proximal to and has a greater radial stiffness than the longitudinal first region, the longitudinal first region comprising a first annular segment and an annular flex segment adjacent to one another, the first annular segment including a proximal first annular stent member and a distal first annular stent member adjacent to one another, each of the proximal and distal first annular stent members having proximal and distal apices arranged in a peak-to-peak relationship with one another, wherein at least a portion of the distal apices and corresponding proximal apices of the respective proximal and distal first annular stent members remain uncoupled to one another, the annular flex segment including at least one second annular stent member having proximal and distal apices arranged in a peak-to-valley relationship with the proximal and distal first annular stent members, wherein a longitudinal tie bar is coupled between one of the proximal apices of the second annular stent member and one of the proximal apices of the distal first annular stent member at a coupling joint, wherein the coupling joint is located where the distal and the corresponding proximal apices of the proximal and distal first annular stent members remain uncoupled to one another.
Glass sheet transport vehicle for handling substantially upright stacks of glass sheets, comprising a supporting fork for passing underneath at least one stack and a supporting frame for supporting a lifted stack, wherein the glass sheet transport vehicle comprises a glass fanning stop element, and the glass fanning stop element can be operatively connected to a stack of glass sheets in such a way that it exerts a pressure on a broad side of the stack of glass sheets and the glass fanning stop element comprises a spring element, and the glass fanning stop element in the unloaded state projects forwards by a predetermined distance out of the plane of the supporting frame, characterized in that the spring deflection of the spring element at least approximately perpendicular to the plane of the supporting frame is at least as great as the distance.
A method for obtaining ready-for-use plant products, comprising the steps of washing and superficially decontaminating the plant products, wherein, during the decontaminating step, the plant products are irradiated with UV-C rays in a treatment chamber, characterized in that the plant products are dried by an air flow coming out of a ventilation device while they are being irradiated with UV-C rays, the air flow being sent in the treatment chamber from the bottom upwards thereby causing the plant products to move with a turbulent motion in the treatment chamber.
An optical media comprising: a substrate; a pre-format layer on one side of the substrate; and a back side coating, wherein the back side coating includes a metalized film, and is optically transparent and electrically conductive; wherein one of the substrate and the pre-format layer is between the back side coating and the other one of the substrate and the pre-format layer. a substrate; a pre-format layer on one side of the substrate; and a back side coating, wherein the back side coating includes a metalized film, and is optically transparent and electrically conductive; wherein one of the substrate and the pre-format layer is between the back side coating and the other one of the substrate and the pre-format layer.
An isolated antibody polypeptide that is a fusion polypeptide comprising a first variable domain and an Fc domain, wherein the first variable domain specifically binds human CD40L, wherein CD40L comprises the amino acid sequence of SEQ ID NO: 1, wherein the first variable domain comprises BMS2h-572-633 having the amino acid sequence of SEQ ID NO: 274, and wherein the Fc domain is an IgG1 Fc domain selected from a CT-Long domain consisting of amino acids 139 to 370 of SEQ ID NO: 1362, a CT-short domain consisting of amino acids 138 to 362 of SEQ ID NO: 1363, an N297Q Long Fc domain consisting of amino acids 139 to 370 of SEQ ID NO: 1364, or an N297Q Short Fc domain consisting of amino acids 138 to 362 of SEQ ID NO: 1365.
Apparatus for supplying user inputs to a computer program, such as a game program, for controlling the game program, the apparatus comprising at least one depressible actuator mechanism, the actuator mechanism comprising an actuator body having a mechanism for manual adjustment of the depressible range of the actuator mechanism mounted therein characterised in that the mechanism for manual adjustment of the depressible range of the actuator mechanism comprises a stopping block having at least two faces, and the actuator body comprises an aperture or cutaway, wherein at least one of said faces has a projection which extends outwardly through the aperture or cutaway in the actuator body such that the projection arrests the motion of the actuator mechanism thereby reducing the depressible range of the actuator mechanism; and wherein the stopping block is rotationally mounted within the actuator body.
A laminated steel sheet for a both-sided resin-coated container, comprising: a steel sheet; a first polyester resin layer formed on a surface of the steel sheet serving as an inner side of a container after the container is formed; and a second polyester resin layer formed on a surface of the steel sheet serving as an outer side of the container after the container is formed, characterized in that the first polyester resin layer includes a polyethylene terephthalate content of 95% by weight or more and has a degree of crystallinity in a range of 3% to 25% measured utilizing the method described in the description, and the second polyester resin layer includes polyethylene terephthalate and polybutylene terephthalate and has a proportion of polybutylene terephthalate in a range of 40% by mass to 80% by weight. a steel sheet; a first polyester resin layer formed on a surface of the steel sheet serving as an inner side of a container after the container is formed; and a second polyester resin layer formed on a surface of the steel sheet serving as an outer side of the container after the container is formed, characterized in that the first polyester resin layer includes a polyethylene terephthalate content of 95% by weight or more and has a degree of crystallinity in a range of 3% to 25% measured utilizing the method described in the description, and the second polyester resin layer includes polyethylene terephthalate and polybutylene terephthalate and has a proportion of polybutylene terephthalate in a range of 40% by mass to 80% by weight.
A method of distributing a video program and information related to the video program, the method comprising: receiving, by a processor of a server, a request for the video program from one of a first device and a second device (32, 33), both registered in an account at the server; and determining a distance between the first device and the second device (32, 33); characterized by: if the distance is less than a threshold, transmitting, by the processor, the video program, but not the information related to the video program, to the first device, and transmitting the information related to the video program, but not the video program, to the second device (32, 33); and if the distance is greater than the threshold, transmitting both the video program and the information related to the video program to either the first device or the second device (32, 33). receiving, by a processor of a server, a request for the video program from one of a first device and a second device (32, 33), both registered in an account at the server; and determining a distance between the first device and the second device (32, 33); characterized by: if the distance is less than a threshold, transmitting, by the processor, the video program, but not the information related to the video program, to the first device, and transmitting the information related to the video program, but not the video program, to the second device (32, 33); and if the distance is greater than the threshold, transmitting both the video program and the information related to the video program to either the first device or the second device (32, 33). if the distance is less than a threshold, transmitting, by the processor, the video program, but not the information related to the video program, to the first device, and transmitting the information related to the video program, but not the video program, to the second device (32, 33); and if the distance is greater than the threshold, transmitting both the video program and the information related to the video program to either the first device or the second device (32, 33).
A clothing packing apparatus for folding an article of clothing, the apparatus comprising: a first portion, and a second portion joined with and foldable relative to said first portion about a first fold line, wherein said second portion has a lower-third area, a central-third area and an upper-third area, wherein said upper-third area is foldable relative to said central-third area about a second fold line, and wherein said lower-third area is foldable relative to said central-third area about a third fold line, characterized in that said first fold line is at least partially within the width of the central-third area, and that said apparatus further includes: a slit extending from said third fold line towards the center of said central-third area of said second portion to partially separate said first portion and said second portion, rounded or tapered edges, pre-formed markings along said first, second and third fold lines, and gripping surfaces on both sides of said apparatus, configured to engage the article of clothing. a first portion, and a second portion joined with and foldable relative to said first portion about a first fold line, wherein said second portion has a lower-third area, a central-third area and an upper-third area, wherein said upper-third area is foldable relative to said central-third area about a second fold line, and wherein said lower-third area is foldable relative to said central-third area about a third fold line, characterized in that said first fold line is at least partially within the width of the central-third area, and that said apparatus further includes: a slit extending from said third fold line towards the center of said central-third area of said second portion to partially separate said first portion and said second portion, rounded or tapered edges, pre-formed markings along said first, second and third fold lines, and gripping surfaces on both sides of said apparatus, configured to engage the article of clothing. a slit extending from said third fold line towards the center of said central-third area of said second portion to partially separate said first portion and said second portion, rounded or tapered edges, pre-formed markings along said first, second and third fold lines, and gripping surfaces on both sides of said apparatus, configured to engage the article of clothing.
Inline cutting system comprising an extruder having an outlet, an outlet line connected with the extruder outlet, wherein the outlet line comprises a side wall surrounding an internal passage and cutting means arranged in connection with the outlet line, wherein said extruder is arranged for continuously producing a meat analogue product and wherein the extruded string of meat analogue product after leaving the extruder is cut into meat pieces by the cutting means, characterised in that said cutting means is extending through the side wall of the outlet line and extends inside said internal passage, that the cutting means comprises at least one cutting edge which is pointed in a substantial axial direction of the outlet line in order to establish a cutting in the longitudinal direction of the string of meat analogue product and that the extruder and the outlet line forms a closed enclosure upstream of the cutting means.
A vine robot tracheal intubation device, comprising an everting primary vine robot attached to a mouthpiece and a smaller diameter everting intubation vine robot associated with the primary everting vine robot, wherein the primary vine robot is shaped and sized to extend to the back of a patient's laryngopharynx when fully actuated and the intubation everting vine robot is shaped and sized to extend from the primary vine robot into the patient's trachea when fully actuated, whereby a lumen is provided by the device from the mouthpiece into the patient's trachea.