A sterile work system for enabling a worker to perform a sterile work required for cultivation inside a sterile chamber of the system having an inside formed as a sterile work space, and enabling a checker to check whether or not the sterile work by a worker has been normally executed in accordance with a work procedure, characterized in that the sterile work system comprises: a headset or speaker for work, adapted to output the work procedure in voice for the worker; and a headset or speaker for check, adapted to output the work procedure in voice for the checker; a monitor, adapted to display the work procedure for the checker; a check input device adapted to allow the checker to input a fact that the work procedure has been normally executed; and a management device adapted for: (i) sending and displaying the work procedure to and on the monitor, sending the work procedure to each of the headset or speaker for work and for check, and causing the headset or speaker for work and for check to each automatically read out and output in voice a sentence of the displayed work procedure; and (ii) receiving a signal input into the check input device; wherein the management device is configured to send and display the work procedure of this time sterile work to the headset or speaker for work and check respectively to output in voice the work procedure; and is further configured such that after receipt of the fact that the work procedure this time has been normally executed from the check input device, the management device sends a work procedure of the next sterile work to the headset or speaker for work and check respectively, thereby repeating a series of these works. a headset or speaker for work, adapted to output the work procedure in voice for the worker; and a headset or speaker for check, adapted to output the work procedure in voice for the checker; a monitor, adapted to display the work procedure for the checker; a check input device adapted to allow the checker to input a fact that the work procedure has been normally executed; and a management device adapted for: (i) sending and displaying the work procedure to and on the monitor, sending the work procedure to each of the headset or speaker for work and for check, and causing the headset or speaker for work and for check to each automatically read out and output in voice a sentence of the displayed work procedure; and (ii) receiving a signal input into the check input device; (i) sending and displaying the work procedure to and on the monitor, sending the work procedure to each of the headset or speaker for work and for check, and causing the headset or speaker for work and for check to each automatically read out and output in voice a sentence of the displayed work procedure; and (ii) receiving a signal input into the check input device; wherein the management device is configured to send and display the work procedure of this time sterile work to the headset or speaker for work and check respectively to output in voice the work procedure; and is further configured such that after receipt of the fact that the work procedure this time has been normally executed from the check input device, the management device sends a work procedure of the next sterile work to the headset or speaker for work and check respectively, thereby repeating a series of these works.