mhurhangee/ep-ind-claims huggingface dataset:
An electronic data processing system comprising: a first application program; an operating system for execution by the electronic data processing system; a virtual bus server application comprising a shared memory and a message router, the message router operable to route data messages between the first application program and a first hardware module as a network element; a first interface providing an interface between the first application program and the virtual bus server application, the first interface capable of communicating with the shared memory of the virtual bus server application; and a second interface providing an interface between the virtual bus server application and the first hardware module, the second interface capable of communicating with the shared memory of the virtual bus server application, characterized in that the first application program is capable of operating in a first mode and a second mode, the first mode comprising software emulation of a vehicle data bus and the first hardware module to develop or test the first application program for proper functionality independent of the proper operation or compatibility of the first hardware module and the second interface; the second mode comprising communications access to the first hardware module via the vehicle data bus, that the first interface is a dynamic link library interface, that the second interface is a dynamic link library interface and that the operating system facilitates communication between the at least two dynamic link libraries in the shared memory. a first application program; an operating system for execution by the electronic data processing system; a virtual bus server application comprising a shared memory and a message router, the message router operable to route data messages between the first application program and a first hardware module as a network element; a first interface providing an interface between the first application program and the virtual bus server application, the first interface capable of communicating with the shared memory of the virtual bus server application; and a second interface providing an interface between the virtual bus server application and the first hardware module, the second interface capable of communicating with the shared memory of the virtual bus server application, characterized in that the first application program is capable of operating in a first mode and a second mode, the first mode comprising software emulation of a vehicle data bus and the first hardware module to develop or test the first application program for proper functionality independent of the proper operation or compatibility of the first hardware module and the second interface; the second mode comprising communications access to the first hardware module via the vehicle data bus, that the first interface is a dynamic link library interface, that the second interface is a dynamic link library interface and that the operating system facilitates communication between the at least two dynamic link libraries in the shared memory.
A patient-specific bicompartmental knee implant for implantation into a patient's joint, the implant comprising: a body having a condylar portion and a trochlear portion, wherein the condylar portion has a shape generally resembling a surface of a condyle of the patient's knee and the trochlear portion has a shape generally resembling the surface of a trochlea of the patient's knee; the condylar portion further having an articular surface, wherein at least a portion of the articular surface of the condylar portion is configured such that a curve of the at least a portion of the articular surface of the condylar portion substantially matches a curve of a corresponding portion of an articular surface of the patient's condyle; and the condylar portion further having a bone-facing surface opposite the articular surface of the condylar portion, wherein at least a first portion (503, 562) on a posterior end of the bone-facing surface of the condylar portion is planar and at least a second portion of the bone-facing surface of the condylar portion substantially matches a corresponding portion of an articular surface of the patient's joint, characterised in that the trochlear portion includes a patellofemoral region having a patient-specific sagittal curvature and an engineered coronal curvature, in which the coronal curvature is selected by choosing one standard curvature from a family of standard curvatures. a body having a condylar portion and a trochlear portion, wherein the condylar portion has a shape generally resembling a surface of a condyle of the patient's knee and the trochlear portion has a shape generally resembling the surface of a trochlea of the patient's knee; the condylar portion further having an articular surface, wherein at least a portion of the articular surface of the condylar portion is configured such that a curve of the at least a portion of the articular surface of the condylar portion substantially matches a curve of a corresponding portion of an articular surface of the patient's condyle; and the condylar portion further having a bone-facing surface opposite the articular surface of the condylar portion, wherein at least a first portion (503, 562) on a posterior end of the bone-facing surface of the condylar portion is planar and at least a second portion of the bone-facing surface of the condylar portion substantially matches a corresponding portion of an articular surface of the patient's joint, characterised in that the trochlear portion includes a patellofemoral region having a patient-specific sagittal curvature and an engineered coronal curvature, in which the coronal curvature is selected by choosing one standard curvature from a family of standard curvatures.
A sustained-release formulation for once-daily oral administration containing Mosapride or its salt as an active ingredient, wherein the formulation comprises: a fast-release layer comprising the active ingredient, a filler, a disintegrating agent, and an additive; and a sustained-release layer comprising the active ingredient, a filler, a disintegrating agent, a controlled-release matrix, and an additive; wherein the formulation complies with the dissolution profile described below when the dissolution profile is measured according to the second method of the of dissolution test (paddle method) of the Korean Pharmacopoeia at 37°C in dissolution media of pH 4.0, 6.8, 1.2 and water, a) the active ingredients contained in the formulation are released in the range of from 25% to 45% in 1 hour, from 60% to 80% in 8 hours, and at least 85% in 24 hours in the dissolution media of pH 4.0, 1.2 and water; and b) the active ingredients contained in the formulation are released 45% or less in 16 hours in the dissolution medium of pH 6.8; wherein the sustained-release layer is prepared by mixing the high-viscosity hydroxypropyl methylcellulose (HPMC) having a viscosity of from 80 Pas to 120 Pas (80,000 cps to 120,000 cps) and the low-viscosity HPMC having a viscosity of 2 Pas to 20 Pas (2,000 cps to 20,000 cps) at a weight ratio in the range of from 2.6:1 to 1:1 as a controlled-release matrix. a fast-release layer comprising the active ingredient, a filler, a disintegrating agent, and an additive; and a sustained-release layer comprising the active ingredient, a filler, a disintegrating agent, a controlled-release matrix, and an additive; wherein the formulation complies with the dissolution profile described below when the dissolution profile is measured according to the second method of the of dissolution test (paddle method) of the Korean Pharmacopoeia at 37°C in dissolution media of pH 4.0, 6.8, 1.2 and water, a) the active ingredients contained in the formulation are released in the range of from 25% to 45% in 1 hour, from 60% to 80% in 8 hours, and at least 85% in 24 hours in the dissolution media of pH 4.0, 1.2 and water; and b) the active ingredients contained in the formulation are released 45% or less in 16 hours in the dissolution medium of pH 6.8; a) the active ingredients contained in the formulation are released in the range of from 25% to 45% in 1 hour, from 60% to 80% in 8 hours, and at least 85% in 24 hours in the dissolution media of pH 4.0, 1.2 and water; and b) the active ingredients contained in the formulation are released 45% or less in 16 hours in the dissolution medium of pH 6.8; wherein the sustained-release layer is prepared by mixing the high-viscosity hydroxypropyl methylcellulose (HPMC) having a viscosity of from 80 Pas to 120 Pas (80,000 cps to 120,000 cps) and the low-viscosity HPMC having a viscosity of 2 Pas to 20 Pas (2,000 cps to 20,000 cps) at a weight ratio in the range of from 2.6:1 to 1:1 as a controlled-release matrix.
A microspheric ionomer having a cross-linked structure, characterized in that the ionomer comprises a structure unit A represented by formula, a structure unit B represented by formula and a cross-linking structural unit provided by a cross-linking agent, wherein, M 1 and M 2 are each independently selected from the group consisting of H, a metal cation, and a linear, branched or cyclic C 1 -C 20 saturated alkyl group preferably selected from the group consisting of methyl, ethyl, n-propyl, isopropyl, tert-butyl, n-butyl, isobutyl, n-pentyl, n-hexyl, n-heptyl, n-octyl, 2-methylbutyl, 3-methylbutyl, cyclohexyl, n-nonyl, isononyl, decyl, 2-propylheptyl, 2-ethylhexyl, dodecyl, tetradecyl, cetyl and stearyl; and R is H or methyl; and at least part of the structure units A in the ionomer comprises the metal cation. M 1 and M 2 are each independently selected from the group consisting of H, a metal cation, and a linear, branched or cyclic C 1 -C 20 saturated alkyl group preferably selected from the group consisting of methyl, ethyl, n-propyl, isopropyl, tert-butyl, n-butyl, isobutyl, n-pentyl, n-hexyl, n-heptyl, n-octyl, 2-methylbutyl, 3-methylbutyl, cyclohexyl, n-nonyl, isononyl, decyl, 2-propylheptyl, 2-ethylhexyl, dodecyl, tetradecyl, cetyl and stearyl; and R is H or methyl; and at least part of the structure units A in the ionomer comprises the metal cation.
A process for the production of acetic anhydride comprising supplying a ketene reactant feed and an acetic acid reactant feed to a unit producing acetic anhydride from ketene and acetic acid, wherein the acetic acid reactant feed is acetylation fluid recovered from a wood acetylation process.
Slide guide for a machine slide of a machine tool, which machine slide is arranged in a linearly slideable manner on a machine bed of the machine tool, which machine bed has at least two support guides and one longitudinal guide, wherein a guide rail is arranged between the support guides and consists of a rib which extends in the longitudinal direction of the machine bed in a central bed part, protrudes perpendicularly to this machine bed and has a projection on its surface remote from the machine bed that overhangs on one side in the transverse direction, characterized in that the projection is releaseably fastened to this surface and is designed as part of a linear drive, and the machine slide has an under-engagement portion which projects into the gap between the projection of the guide rail and the central part of the machine bed.
A bundle section of a pipeline bundle for subsea installation, the bundle section comprising: a rigid elongate carrier pipe having at least one end closed by a transverse bulkhead (26A, 26B); and two or more elongate elements extending along and within the carrier pipe to the bulkhead (26A, 26B), those elements comprising at least one fluid conduit (14, 16) in fluid communication with a respective opening that penetrates the bulkhead (26A, 26B); wherein an outer face of the bulkhead (26A, 26B) has outwardly-facing fluid coupling formations (48, 50) surrounding the or each opening, those formations (48, 50) being arranged to effect leak-tight coupling when forced longitudinally against opposed complementary fluid coupling formations (48, 50); characterised in that: the fluid coupling formations (48, 50) are integral with the outer face of the bulkhead (26A, 26B), and the or each fluid conduit (14,16) is welded to an inner face of the bulkhead (26A, 26B) around the respective opening for leak-tight fluid communication with that opening. a rigid elongate carrier pipe having at least one end closed by a transverse bulkhead (26A, 26B); and two or more elongate elements extending along and within the carrier pipe to the bulkhead (26A, 26B), those elements comprising at least one fluid conduit (14, 16) in fluid communication with a respective opening that penetrates the bulkhead (26A, 26B); wherein an outer face of the bulkhead (26A, 26B) has outwardly-facing fluid coupling formations (48, 50) surrounding the or each opening, those formations (48, 50) being arranged to effect leak-tight coupling when forced longitudinally against opposed complementary fluid coupling formations (48, 50); characterised in that: the fluid coupling formations (48, 50) are integral with the outer face of the bulkhead (26A, 26B), and the or each fluid conduit (14,16) is welded to an inner face of the bulkhead (26A, 26B) around the respective opening for leak-tight fluid communication with that opening. the fluid coupling formations (48, 50) are integral with the outer face of the bulkhead (26A, 26B), and the or each fluid conduit (14,16) is welded to an inner face of the bulkhead (26A, 26B) around the respective opening for leak-tight fluid communication with that opening.
An insertion instrument configured to eject at least one anchor at a target location, the anchor including an anchor body that extends substantially along a direction of elongation, the anchor further including an actuation member that extends from the anchor body substantially along the direction of elongation, the insertion instrument comprising: an access member elongate along a longitudinal direction, the access member defining a distal end that is configured to be at least partially inserted into the target location; an anchor housing that releasably carries the at least one anchor, the anchor housing configured to be aligned with the access member; a pusher member configured to be inserted into the anchor housing and to eject at least one anchor from the anchor housing and out the distal end of the access member; and characterized by: a tension assembly configured to apply a predetermined tension force characteristic to the actuation member, thereby causing the anchor body to expand along a second direction that is angularly offset relative to the direction of elongation, the tension assembly including a translating member configured to translate a predetermined distance from a neutral position to an extended position with respect to the distal end of the access member to apply said tension force to the actuation member so as to cause the anchor body to expand along the second direction. an access member elongate along a longitudinal direction, the access member defining a distal end that is configured to be at least partially inserted into the target location; an anchor housing that releasably carries the at least one anchor, the anchor housing configured to be aligned with the access member; a pusher member configured to be inserted into the anchor housing and to eject at least one anchor from the anchor housing and out the distal end of the access member; and characterized by: a tension assembly configured to apply a predetermined tension force characteristic to the actuation member, thereby causing the anchor body to expand along a second direction that is angularly offset relative to the direction of elongation, the tension assembly including a translating member configured to translate a predetermined distance from a neutral position to an extended position with respect to the distal end of the access member to apply said tension force to the actuation member so as to cause the anchor body to expand along the second direction. a tension assembly configured to apply a predetermined tension force characteristic to the actuation member, thereby causing the anchor body to expand along a second direction that is angularly offset relative to the direction of elongation, the tension assembly including a translating member configured to translate a predetermined distance from a neutral position to an extended position with respect to the distal end of the access member to apply said tension force to the actuation member so as to cause the anchor body to expand along the second direction.
A trailing link unit, in particular for commercial vehicles, with a receiving unit, wherein the trailing link unit has a curved link-side connection region and, adjoining the link-side connection region, a link-side fastening region, wherein the receiving unit has a curved receiving-side connection region, which in an assembled state is arranged opposite the link-side connection region, and has a receiving-side fastening region adjoining the receiving-side fastening region, wherein a fastening means is provided which is adapted, in a mounted state, to engage at least partially, in particular releasably, in each of a link-side and an opposite receiving-side fastening region (18, 22), wherein the link-side and the opposite receiving-side fastening region (16, 20) each have a contour (40, 50) for the positive fixing of an axle, characterized in that the trailing link unit comprises a two-part link element (12, 12a, 12b), wherein a connecting means, in particular a bolt connection or a U-bolt connection or a screw connection or a hook connection or the like connects the two link elements (12, 12a, 12b) to each other and a first part is secured to a second part of the link element (12, 12a, 12b) against a translatory displacement movement by the connecting means, but a rotatory movement of the first part to the second part of the steering element (12, 12a, 12b) relative to each other is possible.
A foam insulation structure comprising (a) a polymer foam layer having opposing major surfaces and gas-filled cells that contain a physical blowing agent, which polymer foam is a reaction product of a foam precursor mixture containing at least one polyisocyanate, water, and the physical blowing agent, and (b) a non-cellular polylactide sheet containing at least 50% by weight of one or more polylactide resins, wherein said non-cellular polylactide sheet (b) contains at least 25 Joules of polylactide crystallites per gram of polylactide resin(s) in the polylactide resin sheet and is sealingly affixed to at least one of said opposing major surfaces of the polymer foam layer, wherein the physical blowing agent is selected from one or more of a hydrocarbon having 3 to 8 carbon atoms; a fluorocarbon, hydrofluorocarbon, fluorochlorocarbon, or hydrofluorochlorocarbon having up to 8 carbon atoms; a hydrohaloolefin having up to 8 carbon atoms; and a dialkyl ether having up to 8 carbon atoms; wherein the amount of crystallinity in the polylactide sheet is measured by differential scanning calorimetry, by heating a 5-10 milligram sample from 25° to 225°C at 20°C/minute under air. wherein the physical blowing agent is selected from one or more of a hydrocarbon having 3 to 8 carbon atoms; a fluorocarbon, hydrofluorocarbon, fluorochlorocarbon, or hydrofluorochlorocarbon having up to 8 carbon atoms; a hydrohaloolefin having up to 8 carbon atoms; and a dialkyl ether having up to 8 carbon atoms; wherein the amount of crystallinity in the polylactide sheet is measured by differential scanning calorimetry, by heating a 5-10 milligram sample from 25° to 225°C at 20°C/minute under air.
A delivery and deployment device (100, 200) configured to deliver an implantable medical device (10, 230) to a chamber of a patient's heart and deploy the IMD (10, 230) therein, the delivery and deployment device (100, 200) comprising: a handle assembly (120, 208); a shaft extending distally from the handle assembly (120, 208), the shaft including a distal region; a device containment housing (12, 108, 202) coupled to the distal region of the shaft and extending distally therefrom, the device containment housing (12, 108, 202) configured to accommodate the IMD (10, 230) therein; at least one of the shaft and device containment housing (12, 108, 202) including a compressible region (222. 322) that is configured to compress by an amount that is related to an applied force; a first position indicator (218, 318, 518) and a second position indicator (220, 320, 520), wherein at least part of the compressible region (222. 322) is situated between the first position indicator (218, 318, 518) and the second position indicator (220, 320, 520); and wherein a force applied to the device containment housing causes the compressible region to compress by an amount that is related to the applied force, which causes a change in distance between the first position indicator (218, 318, 518) and the second position indicator (220, 320, 520), which provides an indication of the applied force. a handle assembly (120, 208); a shaft extending distally from the handle assembly (120, 208), the shaft including a distal region; a device containment housing (12, 108, 202) coupled to the distal region of the shaft and extending distally therefrom, the device containment housing (12, 108, 202) configured to accommodate the IMD (10, 230) therein; at least one of the shaft and device containment housing (12, 108, 202) including a compressible region (222. 322) that is configured to compress by an amount that is related to an applied force; a first position indicator (218, 318, 518) and a second position indicator (220, 320, 520), wherein at least part of the compressible region (222. 322) is situated between the first position indicator (218, 318, 518) and the second position indicator (220, 320, 520); and wherein a force applied to the device containment housing causes the compressible region to compress by an amount that is related to the applied force, which causes a change in distance between the first position indicator (218, 318, 518) and the second position indicator (220, 320, 520), which provides an indication of the applied force.