A method for making a laminated microfluidics device including membrane valves, said method comprising: a) generating a membrane valve assembly comprising: laminating three plastic foils together, the first, top foil comprising one through valve hole for each valve, the second, middle foil having a slit pattern connecting each valve hole of the top foil, and the third, bottom foil having one through valve hole for each valve and one additional hole entering the slit pattern, thereby producing a laminated foil; placing the laminated foil on a mould half having a smooth mould half surface with the bottom foil facing said surface, the surface including one or more perpendicularly protruding cylinders that concentrically fit within the through valve holes of the laminated foil yet leave room for a valve membrane to form, and clamping a second mould half to close the mould; forming said valve membrane by means of injecting and allowing to cure a liquid rubber through a funnel associated with the bottom mould half and the additional hole on the bottom foil layer; and b) laminating said membrane valve assembly and a flow path, the flow path comprising a fourth and a fifth plastic foil, wherein the fourth foil contains a further slit pattern, with the fourth foil on top of the first foil and the fifth foil on top of the fourth foil. a) generating a membrane valve assembly comprising: laminating three plastic foils together, the first, top foil comprising one through valve hole for each valve, the second, middle foil having a slit pattern connecting each valve hole of the top foil, and the third, bottom foil having one through valve hole for each valve and one additional hole entering the slit pattern, thereby producing a laminated foil; placing the laminated foil on a mould half having a smooth mould half surface with the bottom foil facing said surface, the surface including one or more perpendicularly protruding cylinders that concentrically fit within the through valve holes of the laminated foil yet leave room for a valve membrane to form, and clamping a second mould half to close the mould; forming said valve membrane by means of injecting and allowing to cure a liquid rubber through a funnel associated with the bottom mould half and the additional hole on the bottom foil layer; and laminating three plastic foils together, the first, top foil comprising one through valve hole for each valve, the second, middle foil having a slit pattern connecting each valve hole of the top foil, and the third, bottom foil having one through valve hole for each valve and one additional hole entering the slit pattern, thereby producing a laminated foil; placing the laminated foil on a mould half having a smooth mould half surface with the bottom foil facing said surface, the surface including one or more perpendicularly protruding cylinders that concentrically fit within the through valve holes of the laminated foil yet leave room for a valve membrane to form, and clamping a second mould half to close the mould; forming said valve membrane by means of injecting and allowing to cure a liquid rubber through a funnel associated with the bottom mould half and the additional hole on the bottom foil layer; and b) laminating said membrane valve assembly and a flow path, the flow path comprising a fourth and a fifth plastic foil, wherein the fourth foil contains a further slit pattern, with the fourth foil on top of the first foil and the fifth foil on top of the fourth foil.