mhurhangee/ep-ind-claims huggingface dataset:
An in vitro two-step method of producing a population of activated natural killer cells, comprising: (a) seeding a population of hematopoietic stem or progenitor cells in a first medium comprising interleukin-15 (IL-15), Fms-like-tyrosine kinase 3 ligand (Flt3-L), thrombopoietin (Tpo), stem cell factor and interleukin-7 (IL-7), wherein said IL-15, SCF and IL-7 are not comprised within an undefined component of said medium, such that the population expands, and a plurality of hematopoietic stem or progenitor cells within said population of hematopoietic stem or progenitor cells differentiate into NK cells during said expanding; and (b) expanding the cells from the step (a) in a second medium comprising interleukin-2 (IL-2), to produce a population of activated NK cells; wherein the hematopoietic stem or progenitor cells are CD34 +. (a) seeding a population of hematopoietic stem or progenitor cells in a first medium comprising interleukin-15 (IL-15), Fms-like-tyrosine kinase 3 ligand (Flt3-L), thrombopoietin (Tpo), stem cell factor and interleukin-7 (IL-7), wherein said IL-15, SCF and IL-7 are not comprised within an undefined component of said medium, such that the population expands, and a plurality of hematopoietic stem or progenitor cells within said population of hematopoietic stem or progenitor cells differentiate into NK cells during said expanding; and (b) expanding the cells from the step (a) in a second medium comprising interleukin-2 (IL-2), to produce a population of activated NK cells;
A linear motion bearing assembly, comprising: a load bearing plate structure having at least a portion of open axial ball tracks (2302a, 2302b) formed therein, said open axial ball tracks comprised of at least two concentric ball tracks (2302a, 2302b), said ball tracks each including an open load bearing portion, an open return portion and turnarounds interconnecting the load bearing and return portions; a plurality of bearing balls (2202, 2204, 2208, 2210a, 2210b) disposed in the ball tracks; a plurality of load bearing plates (220; 2206) axially positioned adjacent the load bearing plate structure for receiving load from the balls disposed in the load bearing portion of the ball tracks; and a bearing plate to housing intermediary load structure (202; 302) having a uniform substantially cylindrical inner surface in direct contact with said load bearing plates, said bearing plate to housing intermediary load structure being configured and dimensioned to maintain said plurality of load bearing plates in position and for receiving load directly from said load bearing plates, characterized in that said concentric ball tracks (2302a, 2302b) are positioned such that balls (2202, 2204) in the load bearing portions are located most radially inwardly, balls (2210a, 2210b) in return portions immediately adjacent the load bearing portions are located most radially outwardly, and balls in outermost return portions are located radially between the balls (2202, 2204) in the load bearing portions and the balls (2210a, 2210b) in the return portions immediately adjacent the load bearing portions. a load bearing plate structure having at least a portion of open axial ball tracks (2302a, 2302b) formed therein, said open axial ball tracks comprised of at least two concentric ball tracks (2302a, 2302b), said ball tracks each including an open load bearing portion, an open return portion and turnarounds interconnecting the load bearing and return portions; a plurality of bearing balls (2202, 2204, 2208, 2210a, 2210b) disposed in the ball tracks; a plurality of load bearing plates (220; 2206) axially positioned adjacent the load bearing plate structure for receiving load from the balls disposed in the load bearing portion of the ball tracks; and a bearing plate to housing intermediary load structure (202; 302) having a uniform substantially cylindrical inner surface in direct contact with said load bearing plates, said bearing plate to housing intermediary load structure being configured and dimensioned to maintain said plurality of load bearing plates in position and for receiving load directly from said load bearing plates, characterized in that said concentric ball tracks (2302a, 2302b) are positioned such that balls (2202, 2204) in the load bearing portions are located most radially inwardly, balls (2210a, 2210b) in return portions immediately adjacent the load bearing portions are located most radially outwardly, and balls in outermost return portions are located radially between the balls (2202, 2204) in the load bearing portions and the balls (2210a, 2210b) in the return portions immediately adjacent the load bearing portions.
A portable tyre changing stand comprising a frame, a rear support leg, a removable horizontal front leg attached to the lower end of the frame, the frame being located at an angle of 30-90 degrees to the base surface of the tyre changing stand, a removable center shaft perpendicular to the frame and attached to the center of the frame, plastic support surfaces for the rim attached to the frame above and below the center shaft, a bracket attached to the upper end of the frame, a socket attached to the bracket, a rod fixed to the frame near the lower plastic support surface to prevent the rotation of the rim, and characterized in that the rear support leg is rotatable relative to the frame, and the tyre changing stand is further comprising a ratchet mechanism attached to the center shaft, a tyre mounting head and a socket attached to the ratchet mechanism, a removable lever that can be inserted into the socket at the upper end of the frame or the socket attached to the ratchet mechanism, and a plate attached to the lever and to be put in contact with the side surface of the tyre to push the bead of the tyre off from the rim, wherein after inserting the lever in the socket attached to the ratchet mechanism and applying a downward pressure on the lever, movement is given to the tyre mounting head around the center shaft, the ratchet mechanism allowing the lever to be freely returned to its initial position and the movement repeated.
A combination comprising a BTK inhibitor having structure of Formula: or a pharmaceutically acceptable salt thereof, and methotrexate or a pharmaceutically acceptable salt thereof for use in the treatment of rheumatoid arthritis.
A method for maintaining a media stream through a first network equipment while suspending an associated media stream connection (313, 312, 314, 305) in a communication network, the method comprising: • receiving, from a first user equipment, within a second network equipment a trigger for temporarily suspending a media stream connection between the first user equipment and a second user equipment, wherein the trigger comprises a SIP/SDP-command indicating 'call-on-hold'; • sending, by the second network equipment, to the second user equipment a signalling command for maintaining the media stream connection (313, 312, 314, 305), wherein the signalling command for maintaining the media stream (313, 312, 314, 305) comprises a SIP/SDP send/receive command; • blocking, by the second network equipment, the maintained media stream connection between the first user equipment and the second user equipment (313, 312, 314, 305); and • coordinating of sending the signalling command for maintaining the media stream (313, 312, 314, 305) and of blocking the maintained media stream (313, 312, 314, 305) by a central controller within the second network equipment. • receiving, from a first user equipment, within a second network equipment a trigger for temporarily suspending a media stream connection between the first user equipment and a second user equipment, wherein the trigger comprises a SIP/SDP-command indicating 'call-on-hold'; • sending, by the second network equipment, to the second user equipment a signalling command for maintaining the media stream connection (313, 312, 314, 305), wherein the signalling command for maintaining the media stream (313, 312, 314, 305) comprises a SIP/SDP send/receive command; • blocking, by the second network equipment, the maintained media stream connection between the first user equipment and the second user equipment (313, 312, 314, 305); and • coordinating of sending the signalling command for maintaining the media stream (313, 312, 314, 305) and of blocking the maintained media stream (313, 312, 314, 305) by a central controller within the second network equipment.
Electrostatic discharge protective structure for protection of an integrated semiconductor circuit, which is connected between a first potential rail with a first supply potential and a second potential rail with a second supply potential, from electrostatic discharge, with a plurality of laterally constructed bipolar transistors (T1 - T3), the load paths of which are arranged parallel to one another and between the potential rails (4, 5) and the control terminals of which are connected with one of the potential rails (4, 5), and a single doped trough-shaped region is provided integrally in the semiconductor body as a path resistance, which is connected upstream of each control terminal of the bipolar transistors (T1 - T3), and embedded in the semiconductor body is at least one emitter zone and at least collector zone of the first conductor type and at least one base zone of the second, opposite conductor type, wherein the trough-shaped region is formed in the semiconductor body respectively between the zones (12, 13) of the first conductor type and the base zones, characterised in that the trough-shaped region is respectively connected with one of the zones (12, 13) of the first conductor type and has the same doping as, but a smaller doping concentration than the zones (12, 13) so that the effective free path length of the charge carriers to the base zones 915) is prolonged.
A method of delivering content data over a network comprising the steps of: receiving, by a server, a request over a network for content data from a requester, the request including enablement information to enable retrieval of the content data from one or more storage locations; processing, by the server, the enablement information to determine data allocation within the one or more storage locations; retrieving, by the server, content data in the form of separate data components from the one or more storage locations according to the determined data allocation, wherein the separate data components include parity data such that any one or more of the separate data components are recreatable from the remaining separate data components and the parity data; retrieving, by the server, a data map indicating how the separate data components reassemble to form the content data and which parity data corresponds with which of the separate data components; sending, by the server, to the requester the separate data components and the data map; and wherein the enablement information provides information required to determine the allocation and location of the separate data components within the one or more storage locations or provides access to this information. receiving, by a server, a request over a network for content data from a requester, the request including enablement information to enable retrieval of the content data from one or more storage locations; processing, by the server, the enablement information to determine data allocation within the one or more storage locations; retrieving, by the server, content data in the form of separate data components from the one or more storage locations according to the determined data allocation, wherein the separate data components include parity data such that any one or more of the separate data components are recreatable from the remaining separate data components and the parity data; retrieving, by the server, a data map indicating how the separate data components reassemble to form the content data and which parity data corresponds with which of the separate data components; sending, by the server, to the requester the separate data components and the data map; and wherein the enablement information provides information required to determine the allocation and location of the separate data components within the one or more storage locations or provides access to this information.
An agent for changing the color of keratin fibers, in particular human hair, said agent containing, in a cosmetic carrier, (a) at least one substantive dye of formula, where Het1 and Het2 represent, independently of one another, one of structures,,,, or, R1 and R3 represent, independently of one another, a C 1 -C 6 alkyl group or a C 1 -C 6 alkoxyl group, R2 and R4 both represent a hydrogen atom, R5 and R6 represent, independently of one another, a hydrogen atom, a C 1 -C 6 alkyl group or a C 2 -C 6 alkenyl group, Q represents a grouping of formula (VIII), *-(CH 2)n-* (VIII) n represents an integer from 3 to 6, R7 and R10 each represent, independently of one another, a C 1 -C 6 alkyl group or a C 2 -C 6 alkenyl group, R8 and R9 each represent, independently of one another, a hydrogen atom, a C 1 -C 6 alkyl group, a halogen atom from the group chlorine, bromine, fluorine or iodine, a C 1 -C 6 alkoxyl group, or a nitro group, X- represents a physiologically acceptable anion, preferably from the group chloride, bromide, iodide, methyl sulfate, methyl sulfonate, p-toluene sulfonate, acetate, hydrogen sulfate, 1⁄2 sulfate or 1⁄2 tetrachlorozincate. (a) at least one substantive dye of formula, where Het1 and Het2 represent, independently of one another, one of structures,,,, or, R1 and R3 represent, independently of one another, a C 1 -C 6 alkyl group or a C 1 -C 6 alkoxyl group, R2 and R4 both represent a hydrogen atom, R5 and R6 represent, independently of one another, a hydrogen atom, a C 1 -C 6 alkyl group or a C 2 -C 6 alkenyl group, Q represents a grouping of formula (VIII), *-(CH 2)n-* (VIII) n represents an integer from 3 to 6, R7 and R10 each represent, independently of one another, a C 1 -C 6 alkyl group or a C 2 -C 6 alkenyl group, R8 and R9 each represent, independently of one another, a hydrogen atom, a C 1 -C 6 alkyl group, a halogen atom from the group chlorine, bromine, fluorine or iodine, a C 1 -C 6 alkoxyl group, or a nitro group, X- represents a physiologically acceptable anion, preferably from the group chloride, bromide, iodide, methyl sulfate, methyl sulfonate, p-toluene sulfonate, acetate, hydrogen sulfate, 1⁄2 sulfate or 1⁄2 tetrachlorozincate. R1 and R3 represent, independently of one another, a C 1 -C 6 alkyl group or a C 1 -C 6 alkoxyl group, R2 and R4 both represent a hydrogen atom, R5 and R6 represent, independently of one another, a hydrogen atom, a C 1 -C 6 alkyl group or a C 2 -C 6 alkenyl group, Q represents a grouping of formula (VIII), *-(CH 2)n-* (VIII) n represents an integer from 3 to 6, R7 and R10 each represent, independently of one another, a C 1 -C 6 alkyl group or a C 2 -C 6 alkenyl group, R8 and R9 each represent, independently of one another, a hydrogen atom, a C 1 -C 6 alkyl group, a halogen atom from the group chlorine, bromine, fluorine or iodine, a C 1 -C 6 alkoxyl group, or a nitro group, X- represents a physiologically acceptable anion, preferably from the group chloride, bromide, iodide, methyl sulfate, methyl sulfonate, p-toluene sulfonate, acetate, hydrogen sulfate, 1⁄2 sulfate or 1⁄2 tetrachlorozincate.
A punch arrangement for a press, in particular a rotary press, comprising at least one press punch (18, 20) having a punch head (26, 28), a die region (30, 32) and a punch shaft (22, 24) extending between the punch head (26, 28) and the die region (30, 32), further comprising at least one punch guide (14, 16) having at least one guide hole (74, 76) in which the punch shaft (22, 24) of the at least one press punch (18, 20) is guided so as to be axially movable, and at least one sealing sleeve that is variable in length and that surrounds the punch shaft (22, 24) at least in sections, which is held by the first end thereof on the punch shaft (22, 24) or on the die region (30, 32) of the press punch (18, 20), the sealing sleeve being held by the second end thereof on an inner wall of the guide hole (74, 76), characterized in that, when the punch shaft (22, 24) is in the guide hole (74, 76), the second end of the sealing sleeve is held captive in a positive holding position between the inner wall of the guide hole (74, 76) and the punch shaft (22, 24) in such a way that it cannot be released when the press punch is inserted in the guide hole, the second end of the sealing sleeve comprising a fastening ring which is accommodated in an annular groove formed in the inner wall of the guide hole (74, 76), and the sealing sleeve being designed as a boot or corrugated pipe.
A dispenser for dispensing a dose of a gaseous, gas borne or droplet substance from a substance source, the dispenser comprising: a body for receiving a substance source, the body having a mouthpiece; a junction member slideably arranged in the body for movement in a longitudinal axis of the body to release a dose of a substance from a substance source, the junction member comprising a socket for receiving a spout of a substance source; a dispenser driver for moving the junction member in the longitudinal axis of the body to release a dose of a substance from a substance source, the dispenser driver comprising a pivot shaft and a cam arranged on the shaft, the dispenser driver being arranged within the body such that rotation of the pivot shaft causes the cam to rotate and apply a force to the junction member so as to move the junction member in the longitudinal axis; and a cam follower slideably arranged within the body, the cam follower comprising a base and a substantially rigid protrusion, extending from the base, the protrusion, being arranged between the dispenser driver and the junction member such that a force applied by the cam of the dispenser driver to the protrusion, causes the cam follower to slideably move in the longitudinal axis of the body and apply a force to the junction member so as to release a dose of a substance from a substance source. a body for receiving a substance source, the body having a mouthpiece; a junction member slideably arranged in the body for movement in a longitudinal axis of the body to release a dose of a substance from a substance source, the junction member comprising a socket for receiving a spout of a substance source; a dispenser driver for moving the junction member in the longitudinal axis of the body to release a dose of a substance from a substance source, the dispenser driver comprising a pivot shaft and a cam arranged on the shaft, the dispenser driver being arranged within the body such that rotation of the pivot shaft causes the cam to rotate and apply a force to the junction member so as to move the junction member in the longitudinal axis; and a cam follower slideably arranged within the body, the cam follower comprising a base and a substantially rigid protrusion, extending from the base, the protrusion, being arranged between the dispenser driver and the junction member such that a force applied by the cam of the dispenser driver to the protrusion, causes the cam follower to slideably move in the longitudinal axis of the body and apply a force to the junction member so as to release a dose of a substance from a substance source.
A method for controlling digital living network alliance contents, wherein, one Media Access Control MAC recording unit is extended at a Digital Living Network Alliance DLNA device side for recording which MAC addresses are permitted to access or use a service of the DLNA device or prohibited from accessing or using the service of the DLNA device; one service control program is extended at the DLNA device side, and when there is another DLNA device, which interacts with the DLNA device, transmitting a request to the DLNA device, an MAC address of the DLNA device is compared with the MAC address recorded by the MAC recording unit; and if the MAC address of the DLNA device is in a permission list recorded by the MAC recording unit or the MAC address of the DLNA device is not in a prohibition list recorded by the MAC recording unit, then the request will be permitted; otherwise the request will be rejected, characterised in that, if the MAC address of the DLNA device is in the permission list, a parsed-out IP data package is not modified, and an upper level service permits a control unit to obtain a device and service descriptor and permits the control unit to request; otherwise, a FLAG tag is added in the parsed-out IP package, and the request is directly rejected by the DLNA device according to the FLAG.
A method of performing, at a controller, an access to a memory device, the method comprising: transmitting, at the controller, a first command signal, a first address signal, and a first swizzling signal to the memory device to read from a specific subset of memory cells; reading first data bits stored in a memory cell array of the memory device based on the first command signal and the first address signal, wherein the first data bits including at least one front bit and at least one end bit; selecting by a swizzling circuit of the memory device, one of the at least one front bit and the at least one end bit based on the first swizzling signal; and sequentially outputting, at the memory device, at least a part of the first data bits to the controller in a burst manner, based on the first swizzling signal, wherein the at least a part of the first data bits including the selected bit, wherein the at least a part of the first data bits is selected by a plurality of multiplexers included in the memory device and the selection is determined by the first swizzling signal, wherein the number of multiplexers corresponds to a burst length. transmitting, at the controller, a first command signal, a first address signal, and a first swizzling signal to the memory device to read from a specific subset of memory cells; reading first data bits stored in a memory cell array of the memory device based on the first command signal and the first address signal, wherein the first data bits including at least one front bit and at least one end bit; selecting by a swizzling circuit of the memory device, one of the at least one front bit and the at least one end bit based on the first swizzling signal; and sequentially outputting, at the memory device, at least a part of the first data bits to the controller in a burst manner, based on the first swizzling signal, wherein the at least a part of the first data bits including the selected bit, wherein the at least a part of the first data bits is selected by a plurality of multiplexers included in the memory device and the selection is determined by the first swizzling signal, wherein the number of multiplexers corresponds to a burst length.
A low-construction trolley for a wire rope hoist, arranged to travel along a lower flange of a horizontal beam or rail, whereby the trolley comprises a trolley frame; bearing wheels that are attached to the frame of the trolley and arranged to travel on the upper surface of the lower flange of the beam or rail, and at least some of which are driven wheels to move the trolley; a hoisting mechanism comprising a rope drum for a hoisting rope, a hoisting member in cooperation with the hoisting rope for hoisting a load, and a hoisting motor for driving the rope drum; whereby the rope drum is supported to a first side of the trolley frame so that the axle of the rope drum is parallel to the beam or rail, and the hoisting member is arranged to move under the beam or rail; whereby the hoisting rope is led from the rope drum to a fixing point (X; Z) in the trolley frame through at least a rope pulley arrangement (12, 14; 120, 140, 160; 220, 240, 260, 280) of the hoisting member characterised in that the fixing point (X; Z) of the hoisting rope to the trolley frame is located in the longitudinal direction of the trolley, respectively beam or rail, outside the end of the rope drum.