A biopsy apparatus comprising: a radiation source for irradiating radiation toward a subject to be examined from a tube; a radiation detector for detecting radiation which has been irradiated from the radiation source and passed through the subject so as to generate a radiographic image; a stereotactic image generator (16a,50,51,52,24,42) for generating a stereotactic image, which consists of two radiographic images generated by the radiation detector and is represented by a stereotactic coordinate system, by irradiating radiation from the tube disposed at two stereotactic tube positions each having a different angle relative to the subject; a tomosynthesis image generator (16a,50,51,52,24,42,61) for generating a tomosynthesis image, which is represented by a tomosynthesis coordinate system, by irradiating radiation from the tube disposed at a plurality of tomosynthesis tube positions each having a different angle relative to the subject and performing reconstruction of a plurality of tomographic images from a plurality of radiographic images generated by the radiation detector; a biopsy needle driver for driving a biopsy needle based on a biopsy coordinate system calibrated with respect to the stereotactic coordinate system so as to insert the biopsy needle into the subject; a designated-target position identification section for identifying a position of a target designated based on the tomosynthesis image as a first designated position; characterised in that, a target position conversion section for obtaining two projection positions by virtually projecting the first designated position to the image detector from two calibrated-stereotactic tube positions which have been calibrated into the tomosynthesis coordinate system, and converting the first designated position into a second designated position in the stereotactic coordinate system based on the stereotactic tube positions and the projection positions. a radiation source for irradiating radiation toward a subject to be examined from a tube; a radiation detector for detecting radiation which has been irradiated from the radiation source and passed through the subject so as to generate a radiographic image; a stereotactic image generator (16a,50,51,52,24,42) for generating a stereotactic image, which consists of two radiographic images generated by the radiation detector and is represented by a stereotactic coordinate system, by irradiating radiation from the tube disposed at two stereotactic tube positions each having a different angle relative to the subject; a tomosynthesis image generator (16a,50,51,52,24,42,61) for generating a tomosynthesis image, which is represented by a tomosynthesis coordinate system, by irradiating radiation from the tube disposed at a plurality of tomosynthesis tube positions each having a different angle relative to the subject and performing reconstruction of a plurality of tomographic images from a plurality of radiographic images generated by the radiation detector; a biopsy needle driver for driving a biopsy needle based on a biopsy coordinate system calibrated with respect to the stereotactic coordinate system so as to insert the biopsy needle into the subject; a designated-target position identification section for identifying a position of a target designated based on the tomosynthesis image as a first designated position; characterised in that, a target position conversion section for obtaining two projection positions by virtually projecting the first designated position to the image detector from two calibrated-stereotactic tube positions which have been calibrated into the tomosynthesis coordinate system, and converting the first designated position into a second designated position in the stereotactic coordinate system based on the stereotactic tube positions and the projection positions.