A mobile base on which there is to be mounted an X-ray machine comprising: an X-ray tube emitting an X-ray beam along a direction of emission, an X-ray detector aligned in the direction of the emission of the X-rays and positioned so as to be facing the tube, wherein said mobile base comprises at least: two orientable drive wheels (36, 37) driven respectively by a traction motor (34, 35) and a direction motor (42, 43), said motors being coupled to a processing unit, the processing unit comprising a data memory having pre-recorded destinations comprising parking and working positions of the mobile base, and the processing unit being configured to input an instruction value on destination, an instructed value on trajectory and data on position of the X-ray machine, said data on position being provided by at least one sensor (56, 60, 61), and to generate at output the respective direction and speed for each wheel; wherein said sensor comprises a gyrolaser, said gyrolaser comprising a read system capable of computing an absolute position of the X-ray machine in a predefined fixed reference system Ro(Xo,Yo), and an orientation (Ω) of the X-ray machine which corresponds to the orientation of a local reference system R(x,y) in the predefined fixed reference system Ro(Xo,Yo), on the basis of reflections from a plurality of reflectors pre-installed in a room; and wherein the mobile base comprises traction and direction encoders mounted respectively on the traction (34, 35) and direction (42, 43) motors and capable of providing data relative to a position of the X-ray machine. an X-ray tube emitting an X-ray beam along a direction of emission, an X-ray detector aligned in the direction of the emission of the X-rays and positioned so as to be facing the tube, wherein said mobile base comprises at least: two orientable drive wheels (36, 37) driven respectively by a traction motor (34, 35) and a direction motor (42, 43), said motors being coupled to a processing unit, the processing unit comprising a data memory having pre-recorded destinations comprising parking and working positions of the mobile base, and the processing unit being configured to input an instruction value on destination, an instructed value on trajectory and data on position of the X-ray machine, said data on position being provided by at least one sensor (56, 60, 61), and to generate at output the respective direction and speed for each wheel; wherein said sensor comprises a gyrolaser, said gyrolaser comprising a read system capable of computing an absolute position of the X-ray machine in a predefined fixed reference system Ro(Xo,Yo), and an orientation (Ω) of the X-ray machine which corresponds to the orientation of a local reference system R(x,y) in the predefined fixed reference system Ro(Xo,Yo), on the basis of reflections from a plurality of reflectors pre-installed in a room; and wherein the mobile base comprises traction and direction encoders mounted respectively on the traction (34, 35) and direction (42, 43) motors and capable of providing data relative to a position of the X-ray machine. two orientable drive wheels (36, 37) driven respectively by a traction motor (34, 35) and a direction motor (42, 43), said motors being coupled to a processing unit, the processing unit comprising a data memory having pre-recorded destinations comprising parking and working positions of the mobile base, and the processing unit being configured to input an instruction value on destination, an instructed value on trajectory and data on position of the X-ray machine, said data on position being provided by at least one sensor (56, 60, 61), and to generate at output the respective direction and speed for each wheel; wherein said sensor comprises a gyrolaser, said gyrolaser comprising a read system capable of computing an absolute position of the X-ray machine in a predefined fixed reference system Ro(Xo,Yo), and an orientation (Ω) of the X-ray machine which corresponds to the orientation of a local reference system R(x,y) in the predefined fixed reference system Ro(Xo,Yo), on the basis of reflections from a plurality of reflectors pre-installed in a room; and wherein the mobile base comprises traction and direction encoders mounted respectively on the traction (34, 35) and direction (42, 43) motors and capable of providing data relative to a position of the X-ray machine.