An ex vivo method for editing a target locus of a mammalian chromosome, wherein the method comprises transducing a mammalian cell comprising the mammalian chromosome with a replication-defective adeno-associated virus comprising a) an AAV Clade F capsid; and b) a correction genome comprising: (i) an editing element for insertion of one or more nucleotides, deletion of one or more nucleotides, or substitution of one or more nucleotides relative to the target locus, wherein the editing element is selected from an internucleotide bond or a nucleotide sequence for integration into the target locus; (ii) a 5' homologous arm nucleotide sequence 5' of the editing element, having homology to a 5' region of the mammalian chromosome relative to the target locus; and (iii) a 3' homologous arm nucleotide sequence 3' of the editing element, having homology to a 3' region of the mammalian chromosome relative to the target locus, wherein the cell is transduced without co-transducing or co-administering an exogenous nuclease or a nucleotide sequence that encodes an exogenous nuclease, wherein the AAV Clade F capsid comprises: (i) a capsid protein comprising an amino acid sequence having 100% sequence identity with amino acids 203 to 736 of any one of SEQ ID NOs: 2-17; (ii) a capsid protein comprising an amino acid sequence having 100% sequence identity with amino acids 138 to 736 of any one of SEQ ID NOs: 2-17; and/or (iii) a capsid protein comprising an amino acid sequence having 100% sequence identity with amino acids 1 to 736 of any one of SEQ ID NOs: 2-17. a) an AAV Clade F capsid; and b) a correction genome comprising: (i) an editing element for insertion of one or more nucleotides, deletion of one or more nucleotides, or substitution of one or more nucleotides relative to the target locus, wherein the editing element is selected from an internucleotide bond or a nucleotide sequence for integration into the target locus; (ii) a 5' homologous arm nucleotide sequence 5' of the editing element, having homology to a 5' region of the mammalian chromosome relative to the target locus; and (iii) a 3' homologous arm nucleotide sequence 3' of the editing element, having homology to a 3' region of the mammalian chromosome relative to the target locus, wherein the cell is transduced without co-transducing or co-administering an exogenous nuclease or a nucleotide sequence that encodes an exogenous nuclease, wherein the AAV Clade F capsid comprises: (i) a capsid protein comprising an amino acid sequence having 100% sequence identity with amino acids 203 to 736 of any one of SEQ ID NOs: 2-17; (ii) a capsid protein comprising an amino acid sequence having 100% sequence identity with amino acids 138 to 736 of any one of SEQ ID NOs: 2-17; and/or (iii) a capsid protein comprising an amino acid sequence having 100% sequence identity with amino acids 1 to 736 of any one of SEQ ID NOs: 2-17. (i) an editing element for insertion of one or more nucleotides, deletion of one or more nucleotides, or substitution of one or more nucleotides relative to the target locus, wherein the editing element is selected from an internucleotide bond or a nucleotide sequence for integration into the target locus; (ii) a 5' homologous arm nucleotide sequence 5' of the editing element, having homology to a 5' region of the mammalian chromosome relative to the target locus; and (iii) a 3' homologous arm nucleotide sequence 3' of the editing element, having homology to a 3' region of the mammalian chromosome relative to the target locus, (i) a capsid protein comprising an amino acid sequence having 100% sequence identity with amino acids 203 to 736 of any one of SEQ ID NOs: 2-17; (ii) a capsid protein comprising an amino acid sequence having 100% sequence identity with amino acids 138 to 736 of any one of SEQ ID NOs: 2-17; and/or (iii) a capsid protein comprising an amino acid sequence having 100% sequence identity with amino acids 1 to 736 of any one of SEQ ID NOs: 2-17.