A manufacturing machine for the production of disposable cartridges for electronic cigarettes; each disposable cartridge comprises a tubular casing, which contains a quantity of tobacco overlapped by a pad of filtering material and a sealing ring, which is applied and welded to the tubular casing; the manufacturing machine comprises: a first manufacturing drum, which is mounted rotating in a stepwise manner around a first vertical rotation axis and supports a plurality of first groups of first seats, each adapted to house a corresponding tubular casing; a second manufacturing drum, which is mounted rotating in a stepwise manner around a second vertical rotation axis and supports a plurality of second groups of second seats, each adapted to house a corresponding tubular casing; an input unit, which feeds the tubular casings into all the first seats of a first group that is standing still in a first feeding station; at least one filling unit, which feeds the quantities of tobacco into the tubular casings carried by the first seats of a first group that is standing still in a filling station; and a transfer unit which simultaneously transfers all the tubular casings from all the first seats of a first group that is standing still in a transfer station to the corresponding second seats of a second group that is standing still in the transfer station; the manufacturing machine is characterized in that: each group (11, 15) of seats (12, 16) comprises a plurality of seats (12, 16), which are aligned along at least two lines, which are parallel to one another; and a number of filling units is provided equal to the number of lines of each group (11, 15) of seats (12, 16), so that each filling unit feeds the quantities of tobacco into the tubular casings carried by all and only the first seats of a single line of a first group that is standing still in the filling station. a first manufacturing drum, which is mounted rotating in a stepwise manner around a first vertical rotation axis and supports a plurality of first groups of first seats, each adapted to house a corresponding tubular casing; a second manufacturing drum, which is mounted rotating in a stepwise manner around a second vertical rotation axis and supports a plurality of second groups of second seats, each adapted to house a corresponding tubular casing; an input unit, which feeds the tubular casings into all the first seats of a first group that is standing still in a first feeding station; at least one filling unit, which feeds the quantities of tobacco into the tubular casings carried by the first seats of a first group that is standing still in a filling station; and a transfer unit which simultaneously transfers all the tubular casings from all the first seats of a first group that is standing still in a transfer station to the corresponding second seats of a second group that is standing still in the transfer station; the manufacturing machine is characterized in that: each group (11, 15) of seats (12, 16) comprises a plurality of seats (12, 16), which are aligned along at least two lines, which are parallel to one another; and a number of filling units is provided equal to the number of lines of each group (11, 15) of seats (12, 16), so that each filling unit feeds the quantities of tobacco into the tubular casings carried by all and only the first seats of a single line of a first group that is standing still in the filling station. each group (11, 15) of seats (12, 16) comprises a plurality of seats (12, 16), which are aligned along at least two lines, which are parallel to one another; and a number of filling units is provided equal to the number of lines of each group (11, 15) of seats (12, 16), so that each filling unit feeds the quantities of tobacco into the tubular casings carried by all and only the first seats of a single line of a first group that is standing still in the filling station.