A pneumatic tire comprising: a tread portion having a designated installation direction to a vehicle, the tread portion provided with an inboard tread edge (Tei), an outboard tread edge (Teo), a plurality of circumferentially and continuously extending main grooves so as to form a plurality of land portions between the inboard tread edge (Tei) and the outboard tread edge (Teo) and a plurality of lateral grooves; the main grooves comprising an inboard shoulder main groove arranged proximate to the inboard tread edge (Tei), an outboard shoulder main groove arranged proximate to the outboard tread edge (Teo), an inboard center main groove arranged between the inboard shoulder main groove and a tire equator and an outboard center main groove arranged between the outboard shoulder main groove and the tire equator; characterized by the lateral grooves comprising a plurality of inboard shoulder lateral grooves extending axially inward from the inboard tread edge (Tei) and a plurality of outboard shoulder lateral grooves extending axially inward from the outboard tread edge (Teo); the outboard shoulder lateral grooves comprising a plurality of first outboard shoulder lateral grooves each having an axially inner end positioned between the outboard shoulder main groove and the outboard center main groove, and a plurality of second outboard shoulder lateral grooves each having an axially inner end positioned between the outboard shoulder main groove and the outboard tread edge (Teo); and the inboard shoulder lateral grooves comprising a plurality of first inboard shoulder lateral grooves each having an axially inner end positioned between the inboard shoulder main groove and the inboard center main groove, wherein the number of the first inboard shoulder lateral grooves is greater than the number of the first outboard shoulder lateral grooves. a tread portion having a designated installation direction to a vehicle, the tread portion provided with an inboard tread edge (Tei), an outboard tread edge (Teo), a plurality of circumferentially and continuously extending main grooves so as to form a plurality of land portions between the inboard tread edge (Tei) and the outboard tread edge (Teo) and a plurality of lateral grooves; the main grooves comprising an inboard shoulder main groove arranged proximate to the inboard tread edge (Tei), an outboard shoulder main groove arranged proximate to the outboard tread edge (Teo), an inboard center main groove arranged between the inboard shoulder main groove and a tire equator and an outboard center main groove arranged between the outboard shoulder main groove and the tire equator; characterized by the lateral grooves comprising a plurality of inboard shoulder lateral grooves extending axially inward from the inboard tread edge (Tei) and a plurality of outboard shoulder lateral grooves extending axially inward from the outboard tread edge (Teo); the outboard shoulder lateral grooves comprising a plurality of first outboard shoulder lateral grooves each having an axially inner end positioned between the outboard shoulder main groove and the outboard center main groove, and a plurality of second outboard shoulder lateral grooves each having an axially inner end positioned between the outboard shoulder main groove and the outboard tread edge (Teo); and the inboard shoulder lateral grooves comprising a plurality of first inboard shoulder lateral grooves each having an axially inner end positioned between the inboard shoulder main groove and the inboard center main groove, wherein the number of the first inboard shoulder lateral grooves is greater than the number of the first outboard shoulder lateral grooves.