Microfluidic plate comprising a plurality of microfluidic networks and inlets providing access to the microfluidic networks, wherein; - each microfluidic network comprises a capillary pressure barrier and extends through a first plane, - each inlet is formed by an inlet chamber having a bottom surface, - a support structure is provided above each inlet, which support structure defines an opening and comprises at least one support member positioned at the opening such that a circle can be defined in a second plane extending parallel to the first plane, which circle has the largest possible diameter while being completely located within the opening and in contact with the at least one support member, wherein the opening has a non-circular form at the second plane, and - the support structure is configured such that a first empty space is formed, which first empty space extends from the second plane towards the inlet chamber and has the form of a right circular cone or a truncated right circular cone, wherein the circular forms a base plane of the right circular cone or the truncated right circular cone, - the microfluidic plate comprises the following features A or B; A) an apex of the right circular cone or an apical surface of the truncated right circular cone is located in the inlet chamber and on the bottom surface, or B) an apex of the right circular cone or an apical surface of the truncated right circular cone is located vertically above or in the inlet chamber and at a distance from the bottom surface, wherein an additional empty space is formed extending from the apex or the apical surface until the bottom surface, and - a second empty space is formed, which second empty space extends from the second plane into the inlet chamber and is located outside the first empty space, wherein the second empty space forms a vent to allow fluid communication between the inlet chamber and the surrounding environment when the end of a dispensing part is received in the opening and supported by the at least one support member, said end having the form of a right circular cone or a truncated right circular cone. - each microfluidic network comprises a capillary pressure barrier and extends through a first plane, - each inlet is formed by an inlet chamber having a bottom surface, - a support structure is provided above each inlet, which support structure defines an opening and comprises at least one support member positioned at the opening such that a circle can be defined in a second plane extending parallel to the first plane, which circle has the largest possible diameter while being completely located within the opening and in contact with the at least one support member, wherein the opening has a non-circular form at the second plane, and - the support structure is configured such that a first empty space is formed, which first empty space extends from the second plane towards the inlet chamber and has the form of a right circular cone or a truncated right circular cone, wherein the circular forms a base plane of the right circular cone or the truncated right circular cone, - the microfluidic plate comprises the following features A or B; A) an apex of the right circular cone or an apical surface of the truncated right circular cone is located in the inlet chamber and on the bottom surface, or B) an apex of the right circular cone or an apical surface of the truncated right circular cone is located vertically above or in the inlet chamber and at a distance from the bottom surface, wherein an additional empty space is formed extending from the apex or the apical surface until the bottom surface, and A) an apex of the right circular cone or an apical surface of the truncated right circular cone is located in the inlet chamber and on the bottom surface, or B) an apex of the right circular cone or an apical surface of the truncated right circular cone is located vertically above or in the inlet chamber and at a distance from the bottom surface, wherein an additional empty space is formed extending from the apex or the apical surface until the bottom surface, and - a second empty space is formed, which second empty space extends from the second plane into the inlet chamber and is located outside the first empty space, wherein the second empty space forms a vent to allow fluid communication between the inlet chamber and the surrounding environment when the end of a dispensing part is received in the opening and supported by the at least one support member, said end having the form of a right circular cone or a truncated right circular cone.