mhurhangee/ep-ind-claims huggingface dataset:
A method of assessing the ability of a candidate therapeutic agent to reverse, reduce or prevent renal injury by a potential toxic agent, the method comprising: (a) contacting the potential toxic agent with a three-dimensional, engineered, bioprinted, biological renal tubule model comprising: (i) a layer of renal interstitial tissue, the renal interstitial tissue comprising renal fibroblasts and endothelial cells; and (ii) a layer of renal epithelial tissue, the renal epithelial tissue comprising renal tubular epithelial cells, to form the three-dimensional, engineered, biological renal tubule model; provided that the interstitial tissue comprises an interstitial bio-ink comprising renal fibroblasts and endothelial cells, and the epithelial tissue comprises an epithelial bio-ink comprising renal tubular epithelial cells; (b) contacting the renal tubule model with the candidate therapeutic agent; (c) determining the viability or functionality of the renal tubular epithelial cells; and (d) assessing the ability of the candidate therapeutic agent to reverse, reduce or prevent renal injury by the potential toxic agent based on the determined viability or functionality of the renal tubular epithelial cells compared to a control renal tubule model that has not been contacted with the candidate therapeutic agent. (a) contacting the potential toxic agent with a three-dimensional, engineered, bioprinted, biological renal tubule model comprising: (i) a layer of renal interstitial tissue, the renal interstitial tissue comprising renal fibroblasts and endothelial cells; and (ii) a layer of renal epithelial tissue, the renal epithelial tissue comprising renal tubular epithelial cells, to form the three-dimensional, engineered, biological renal tubule model; provided that the interstitial tissue comprises an interstitial bio-ink comprising renal fibroblasts and endothelial cells, and the epithelial tissue comprises an epithelial bio-ink comprising renal tubular epithelial cells; (i) a layer of renal interstitial tissue, the renal interstitial tissue comprising renal fibroblasts and endothelial cells; and (ii) a layer of renal epithelial tissue, the renal epithelial tissue comprising renal tubular epithelial cells, to form the three-dimensional, engineered, biological renal tubule model; (b) contacting the renal tubule model with the candidate therapeutic agent; (c) determining the viability or functionality of the renal tubular epithelial cells; and (d) assessing the ability of the candidate therapeutic agent to reverse, reduce or prevent renal injury by the potential toxic agent based on the determined viability or functionality of the renal tubular epithelial cells compared to a control renal tubule model that has not been contacted with the candidate therapeutic agent.
An information communication device for a vehicle including a determination processing section that brings transmission of vehicle information to an external information storage into a permission state with a user permission signal input state as a condition and that brings the transmission of the vehicle information to the external information storage into a non-permission state with a user non-permission signal input state as a condition, wherein on receipt of a specified trigger signal, the information communication device for a vehicle transmits the vehicle information, which includes information from a time period before an input time point of the specified trigger signal, to the external information storage in the case that transmission of vehicle information to an external information storage is currently in a transmission permission state, characterized in that under a condition that the user non-permission signal input state is switched to the user permission signal input state, the determination processing section maintains the transmission of the vehicle information to the external information storage in the non-permission state for a specified period, wherein the specified period is equal to or longer than the time period before the input time point of the specified trigger signal from which the vehicle information to be transmitted to the external information storage contains information. a determination processing section that brings transmission of vehicle information to an external information storage into a permission state with a user permission signal input state as a condition and that brings the transmission of the vehicle information to the external information storage into a non-permission state with a user non-permission signal input state as a condition, wherein on receipt of a specified trigger signal, the information communication device for a vehicle transmits the vehicle information, which includes information from a time period before an input time point of the specified trigger signal, to the external information storage in the case that transmission of vehicle information to an external information storage is currently in a transmission permission state, characterized in that under a condition that the user non-permission signal input state is switched to the user permission signal input state, the determination processing section maintains the transmission of the vehicle information to the external information storage in the non-permission state for a specified period, wherein the specified period is equal to or longer than the time period before the input time point of the specified trigger signal from which the vehicle information to be transmitted to the external information storage contains information.
Dispenser for pasty compounds, comprising a tubular compound housing having a follower plunger and a head piece which is guided relative to an upper tube piece and has a metering chamber with which an inlet valve and a mouthpiece channel are associated, a spring element which extends from the head piece to the upper tube piece being provided in order for the head piece to spring back into the starting position, which spring element extends between parallel annular walls (16, 32) of the head piece and the compound housing, rests thereon by means of two legs (28, 29) that roll between these parallel annular walls (16, 32), and opens and closes the mouthpiece channel when the head piece is actuated, characterised in that the resting legs (28, 29) of the spring element form a U-shaped space which has a rounded base and is open towards the metering chamber, an outer leg of which continues upwards into a sealing tongue that extends into the mouthpiece channel and pivots away in the opening and discharging direction in the presence of discharging pressure.
A label comprising: a tag stock having a first and second face, wherein a first adhesive layer having a first and second face is adhered to the second face of the tag stock via the first face of the adhesive layer, a liner adhered to the second face of the first adhesive layer, an RFID component having a total area, wherein the RFID component is located on the second face of the tag stock characterized in that a periphery of the first face of the first adhesive layer extends beyond the total area of the RFID component such that the second face of the tag stock is in contact with both the RFID component and the first adhesive layer and the first adhesive layer adheres the RFID component to the second face of the tag stock, wherein the liner remains part of the label when the label is removed from a web. a tag stock having a first and second face, wherein a first adhesive layer having a first and second face is adhered to the second face of the tag stock via the first face of the adhesive layer, a liner adhered to the second face of the first adhesive layer, an RFID component having a total area, wherein the RFID component is located on the second face of the tag stock characterized in that a periphery of the first face of the first adhesive layer extends beyond the total area of the RFID component such that the second face of the tag stock is in contact with both the RFID component and the first adhesive layer and the first adhesive layer adheres the RFID component to the second face of the tag stock, wherein the liner remains part of the label when the label is removed from a web.
An image forming apparatus comprising: an image forming portion (6, 6Y, 6M, 6C, 6K) including a photosensitive member (7, 7Y, 7M, 7C, 7K) and a developing portion (9, 9Y, 9M, 9C, 9K) configured to develop, with toner, an electrostatic latent image formed on the photosensitive member (7, 7Y, 7M, 7C, 7K), the image forming portion (6, 6Y, 6M, 6C, 6K) being configured to form an image on a sheet; and a first frame including an upper space supporting the image forming portion (6, 6Y, 6M, 6C, 6K), and a lower space under the upper space, wherein an accommodating portion configured to accommodate the sheet and a feeding portion configured to feed the sheet accommodated in the accommodating portion are capable of being provided in the lower space, characterized in that a supply container (13, 13Y, 13M, 13C, 13K) configured to contain the toner to be supplied to the developing portion (9, 9Y, 9M, 9C, 9K) of the image forming portion (6, 6Y, 6M, 6C, 6K) is capable of being provided in the lower space together with a second frame which is mountable to a lower portion of the first frame, and wherein either a unit of the accommodating portion and the feeding portion or the supply container (13, 13Y, 13M, 13C, 13K) is capable of being provided in the lower space which is a common space for the unit and the supply container (13, 13Y, 13M, 13C, 13K). an image forming portion (6, 6Y, 6M, 6C, 6K) including a photosensitive member (7, 7Y, 7M, 7C, 7K) and a developing portion (9, 9Y, 9M, 9C, 9K) configured to develop, with toner, an electrostatic latent image formed on the photosensitive member (7, 7Y, 7M, 7C, 7K), the image forming portion (6, 6Y, 6M, 6C, 6K) being configured to form an image on a sheet; and a first frame including an upper space supporting the image forming portion (6, 6Y, 6M, 6C, 6K), and a lower space under the upper space, wherein an accommodating portion configured to accommodate the sheet and a feeding portion configured to feed the sheet accommodated in the accommodating portion are capable of being provided in the lower space, characterized in that a supply container (13, 13Y, 13M, 13C, 13K) configured to contain the toner to be supplied to the developing portion (9, 9Y, 9M, 9C, 9K) of the image forming portion (6, 6Y, 6M, 6C, 6K) is capable of being provided in the lower space together with a second frame which is mountable to a lower portion of the first frame, and wherein either a unit of the accommodating portion and the feeding portion or the supply container (13, 13Y, 13M, 13C, 13K) is capable of being provided in the lower space which is a common space for the unit and the supply container (13, 13Y, 13M, 13C, 13K).
A curable composition comprising: a cationic polymerizable compound; a thermal polymerization initiator; and a storage stabilizer, wherein the cationic polymerizable compound includes at least two selected from the group consisting of a glycidyl ether compound, an alicyclic epoxy compound, and an oxetane compound, a content of the thermal polymerization initiator is 0.3 to 3 parts by mass with respect to 100 parts by mass of the cationic polymerizable compound, and chain curing is enabled by thermal energy generated by a polymerization reaction of the cationic polymerizable compound, characterized in that the storage stabilizer is at least one selected from the group consisting of sulfonium salts represented by the following Formula: wherein R 6 represents an acetyl group or a methoxycarbonyl group, and A represents CH 3 SO 4. a cationic polymerizable compound; a thermal polymerization initiator; and a storage stabilizer, wherein the cationic polymerizable compound includes at least two selected from the group consisting of a glycidyl ether compound, an alicyclic epoxy compound, and an oxetane compound, a content of the thermal polymerization initiator is 0.3 to 3 parts by mass with respect to 100 parts by mass of the cationic polymerizable compound, and chain curing is enabled by thermal energy generated by a polymerization reaction of the cationic polymerizable compound, characterized in that the storage stabilizer is at least one selected from the group consisting of sulfonium salts represented by the following Formula: wherein R 6 represents an acetyl group or a methoxycarbonyl group, and A represents CH 3 SO 4.
A method for synchronizing PWM control signals of inverters, wherein a direct current voltage terminal of an inverter circuit of an inverter among the inverters is connected to an external direct current power supply, an alternating current voltage terminal of the inverter circuit of the inverter is connected to an alternating current point of common coupling of a power grid, and the method comprises: obtaining a phase of an alternating current voltage of the power grid, wherein the obtaining the phase of the alternating current voltage of the power grid comprises: phase-locking the alternating current voltage of the power grid to obtain a phase waveform of an alternating current voltage of the power grid; and obtaining the phase of the alternating current voltage from the phase waveform; determining a time period during which the phase of the alternating current voltage varies within a preset phase threshold interval, when it is detected that the phase of the alternating current voltage has reached a phase threshold, wherein the phase threshold is a start phase of the preset phase threshold interval; calculate a period of a preset carrier wave based on a preset carrier wave ratio and the time period; generating the preset carrier wave based on the period of the preset carrier wave; and generating a PWM control signal of the inverter based on a PWM modulation signal and the preset carrier wave, so that the inverter circuit of the inverter converts a direct current voltage of the external direct current power supply into the alternating current voltage of the power grid based on the PWM control signal. obtaining a phase of an alternating current voltage of the power grid, wherein the obtaining the phase of the alternating current voltage of the power grid comprises: phase-locking the alternating current voltage of the power grid to obtain a phase waveform of an alternating current voltage of the power grid; and obtaining the phase of the alternating current voltage from the phase waveform; determining a time period during which the phase of the alternating current voltage varies within a preset phase threshold interval, when it is detected that the phase of the alternating current voltage has reached a phase threshold, wherein the phase threshold is a start phase of the preset phase threshold interval; calculate a period of a preset carrier wave based on a preset carrier wave ratio and the time period; generating the preset carrier wave based on the period of the preset carrier wave; and generating a PWM control signal of the inverter based on a PWM modulation signal and the preset carrier wave, so that the inverter circuit of the inverter converts a direct current voltage of the external direct current power supply into the alternating current voltage of the power grid based on the PWM control signal.
A retractable staircase comprising: a first side stringer and a second, substantially parallel, side stringer connected by a plurality of steps, the first side stringer having means to be fixedly attached to a wall and the second side stringer being pivotally movable about the first side stringer between an extended position, where the steps lie substantially horizontally between the stringers (12, 14), and a retracted position where the steps lie substantially vertically between the stringers (12, 14) characterized in that each side stringer (12, 14) comprises a plurality of modular sections (32, 37) to enable selecting the length of the staircase. a first side stringer and a second, substantially parallel, side stringer connected by a plurality of steps, the first side stringer having means to be fixedly attached to a wall and the second side stringer being pivotally movable about the first side stringer between an extended position, where the steps lie substantially horizontally between the stringers (12, 14), and a retracted position where the steps lie substantially vertically between the stringers (12, 14) characterized in that each side stringer (12, 14) comprises a plurality of modular sections (32, 37) to enable selecting the length of the staircase.
Extractor device, comprising at least one extractor hood and at least one air processing means, wherein the air processing means is an active air processing means, which is arranged in the extractor hood or separately from the extractor hood, characterised in that the air processing means has at least one filter element, which is an odour filter element, and an air treatment device for air treatment by means of dielectric barrier discharge, and the extractor device has at least one determination unit for determining the residual service life of at least the odour filter element or the air treatment device of the air processing means by considering at least one operating mode of the extractor hood and the determination unit is connected to at least the controller or the fan of the extractor hood to obtain information about an operating state of the extractor hood, which illustrates the operating duration and/or power stage of the fan of the extractor hood, and the extractor device has a display device for displaying the residual duration of the odour filter element or the air treatment device of the air processing means.
A pharmaceutical composition, wherein the composition is a coated tablet, wherein the coated tablet is a tablet coated with at least one coating agent selected from the group consisting of hypromellose, methyl cellulose, ethyl cellulose, hydroxypropyl cellulose, and polyvinyl alcohol, wherein the tablet comprises: N 1 -(5-chloropyridin-2-yl)-N 2 -((1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-{[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}cyclohexyl)ethanediamide, represented by formula:, a pharmacologically acceptable salt thereof, or a hydrate of any of these; a sugar alcohol; and a water-swelling additive. N 1 -(5-chloropyridin-2-yl)-N 2 -((1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-{[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}cyclohexyl)ethanediamide, represented by formula:, a pharmacologically acceptable salt thereof, or a hydrate of any of these; a sugar alcohol; and a water-swelling additive.
A fuel supply device (1; 1A; 1 B) configured to supply a fuel to an engine, the fuel supply device comprising: a fuel tank (3; 3B; 3C) containing a fuel storage region comprising a sealed space configured to store the fuel; a fuel path being connected or connectable to the engine and to the fuel tank and comprising a vaporized-liquid fuel mixture suction portion for sucking a vaporized-liquid fuel mixture, the vaporized-liquid fuel mixture being provided by mixing of a vaporized fuel with or into a liquid fuel, the vaporized fuel being provided from the liquid fuel stored in the fuel storage region; characterised by a fuel pump (5; 5C) disposed in the fuel path and configured to provide a negative pressure in a pump suction port connected to the vaporized-liquid fuel mixture suction portion wherein the vaporized-liquid fuel mixture suction portion comprises: a liquid fuel suction port provided within the fuel storage region; a vaporized fuel suction port provided within the fuel storage region; and a vaporized-liquid fuel mixture path configured to mix the vaporized fuel sucked through the vaporized fuel suction port with or into the liquid fuel sucked through the liquid fuel suction port. a fuel tank (3; 3B; 3C) containing a fuel storage region comprising a sealed space configured to store the fuel; a fuel path being connected or connectable to the engine and to the fuel tank and comprising a vaporized-liquid fuel mixture suction portion for sucking a vaporized-liquid fuel mixture, the vaporized-liquid fuel mixture being provided by mixing of a vaporized fuel with or into a liquid fuel, the vaporized fuel being provided from the liquid fuel stored in the fuel storage region; characterised by a fuel pump (5; 5C) disposed in the fuel path and configured to provide a negative pressure in a pump suction port connected to the vaporized-liquid fuel mixture suction portion wherein the vaporized-liquid fuel mixture suction portion comprises: a liquid fuel suction port provided within the fuel storage region; a vaporized fuel suction port provided within the fuel storage region; and a vaporized-liquid fuel mixture path configured to mix the vaporized fuel sucked through the vaporized fuel suction port with or into the liquid fuel sucked through the liquid fuel suction port. a liquid fuel suction port provided within the fuel storage region; a vaporized fuel suction port provided within the fuel storage region; and a vaporized-liquid fuel mixture path configured to mix the vaporized fuel sucked through the vaporized fuel suction port with or into the liquid fuel sucked through the liquid fuel suction port.
An operator cabinet for operating a technical system, the cabinet comprising a wall having a front side, a rear side and a cutout provided with an inner edge, and further comprising an operator terminal installed in the cutout, wherein the operator terminal comprises a display for displaying at least one state of the technical system, a frame having an outer frame edge, a plurality of bolts each having a first end and a second end, and a plate with an outer plate edge, the outer frame edge being dimensioned so as to be larger than the inner edge of the cutout, with the result that, when installed, the frame can rest with a frame resting area (F R) on the front side of the wall, the outer plate edge being dimensioned so as to be larger than the inner edge of the cutout, with the result that, when installed, the plate can rest with a plate resting area (F P) on the rear side of the wall, the plate having a plurality of holes, each hole being arranged in a position corresponding to one bolt, with the result that, when installed, the corresponding bolt can engage in said hole, each bolt being arranged with its first end on the frame, and each bolt extending, when installed, with its second end through the cutout, characterized in that the operator terminal further comprises a transparent element on which the display is arranged, wherein the frame surrounds the transparent element, and wherein each bolt is fastened with its first end in the frame and is integrated into the operator terminal by means of an integral design, a welded joint or an adhesive bonding.
A user equipment for a mobile telecommunications system comprising circuitry including a receiver and a transmitter and being configured to communicate with a new radio NR base station and a LTE base station, wherein the circuitry is further configured to: indicate a coexistence indication to the new radio base station or to the LTE base station, wherein the coexistence indication includes information about a coexistence of new radio and LTE transmission; and receive a power control instruction for controlling power output of the transmitter, based on the coexistence indication, wherein the coexistence indication is indicated when a predefined combination of predetermined problematic band combinations resulting in a double peak situation of a new radio transmission band and a LTE transmission band is detected. indicate a coexistence indication to the new radio base station or to the LTE base station, wherein the coexistence indication includes information about a coexistence of new radio and LTE transmission; and receive a power control instruction for controlling power output of the transmitter, based on the coexistence indication, wherein the coexistence indication is indicated when a predefined combination of predetermined problematic band combinations resulting in a double peak situation of a new radio transmission band and a LTE transmission band is detected.