A method of preparing a material in the form of interpenetrating polymers network associating a physical gel of fibrin and a polyethylene glycol network, comprising the following steps: i.preparing a mixture by introducing into a buffer - a fibrinogen solution - monomers of formula: X 1 - (CH 2 -CH 2 -O)n-X 2 wherein X 1 and X 2 are identical or different chemical group selected from the group comprising vinyl, acrylate, methacrylate or allyl and n is a number between 1 and 140, - optionally monomers of formula selected from polyethylene glycol derivatives having a group selected from the group comprising-CH 3, -NH 2, -OH, -CH 2 CH 3, vinyl, acrylate, methacrylate or allyl; acrylate derivatives, methacrylate and styrene selected from the group comprising hydroxyethylmethacrylate, hydroxyethylacrylate, vinyl acetate, N-vinyl pyrrolidone, N-vinylpyridine, acrylonitrile, acrylic acid, sodium styrene sulfonate, (vinylbenzyl)trimethylammonium bromide, (vinylbenzyl)trimethylammonium chloride, trimethylvinyloxycarbonylmethyl-ammonium chloride, vinyloxycarbonylmethyl-ammonium bromide, triethyl-2-vinyloxycarbonyl-ethyl)-ammonium bromide, allyloxycarbonylmethyl-trimethyl ammonium bromide, poly(ethylene glycol) methacrylate, poly(ethylene glycol) acrylate, - a polymerization initiator; ii. preparing a reaction mixture by adding a thrombin solution to the mixture prepared in i); iii. incubating the reaction mixture obtained in ii) to a temperature between 20 and 40° C; iv. performing a polymerization and crosslinking of the monomers of formula optionally with monomers of formula. i.preparing a mixture by introducing into a buffer - a fibrinogen solution - monomers of formula: X 1 - (CH 2 -CH 2 -O)n-X 2 wherein X 1 and X 2 are identical or different chemical group selected from the group comprising vinyl, acrylate, methacrylate or allyl and n is a number between 1 and 140, - optionally monomers of formula selected from polyethylene glycol derivatives having a group selected from the group comprising-CH 3, -NH 2, -OH, -CH 2 CH 3, vinyl, acrylate, methacrylate or allyl; acrylate derivatives, methacrylate and styrene selected from the group comprising hydroxyethylmethacrylate, hydroxyethylacrylate, vinyl acetate, N-vinyl pyrrolidone, N-vinylpyridine, acrylonitrile, acrylic acid, sodium styrene sulfonate, (vinylbenzyl)trimethylammonium bromide, (vinylbenzyl)trimethylammonium chloride, trimethylvinyloxycarbonylmethyl-ammonium chloride, vinyloxycarbonylmethyl-ammonium bromide, triethyl-2-vinyloxycarbonyl-ethyl)-ammonium bromide, allyloxycarbonylmethyl-trimethyl ammonium bromide, poly(ethylene glycol) methacrylate, poly(ethylene glycol) acrylate, - a polymerization initiator; - a fibrinogen solution - monomers of formula: X 1 - (CH 2 -CH 2 -O)n-X 2 wherein X 1 and X 2 are identical or different chemical group selected from the group comprising vinyl, acrylate, methacrylate or allyl and n is a number between 1 and 140, - optionally monomers of formula selected from polyethylene glycol derivatives having a group selected from the group comprising-CH 3, -NH 2, -OH, -CH 2 CH 3, vinyl, acrylate, methacrylate or allyl; acrylate derivatives, methacrylate and styrene selected from the group comprising hydroxyethylmethacrylate, hydroxyethylacrylate, vinyl acetate, N-vinyl pyrrolidone, N-vinylpyridine, acrylonitrile, acrylic acid, sodium styrene sulfonate, (vinylbenzyl)trimethylammonium bromide, (vinylbenzyl)trimethylammonium chloride, trimethylvinyloxycarbonylmethyl-ammonium chloride, vinyloxycarbonylmethyl-ammonium bromide, triethyl-2-vinyloxycarbonyl-ethyl)-ammonium bromide, allyloxycarbonylmethyl-trimethyl ammonium bromide, poly(ethylene glycol) methacrylate, poly(ethylene glycol) acrylate, - a polymerization initiator; ii. preparing a reaction mixture by adding a thrombin solution to the mixture prepared in i); iii. incubating the reaction mixture obtained in ii) to a temperature between 20 and 40° C; iv. performing a polymerization and crosslinking of the monomers of formula optionally with monomers of formula.