mhurhangee/ep-ind-claims huggingface dataset:
A hepcidin antagonist for use in the treatment of psoriasis, wherein said hepcidin antagonist is administered topically to the skin, and wherein said antagonist is: - an inhibitor of the hepcidin expression selected from the group consisting of erythropoietin and an oligonucleotide sequence targeting the hepcidin gene as an antisense oligonucleotide, siRNA, shRNA or a ribozyme; or - an inhibitor of the hepcidin activity selected form the group consisting of anti-hepcidin antibodies, anti-hepcidin aptamers, lexaptepid pegol and the PRS-080 compound. - an inhibitor of the hepcidin expression selected from the group consisting of erythropoietin and an oligonucleotide sequence targeting the hepcidin gene as an antisense oligonucleotide, siRNA, shRNA or a ribozyme; or - an inhibitor of the hepcidin activity selected form the group consisting of anti-hepcidin antibodies, anti-hepcidin aptamers, lexaptepid pegol and the PRS-080 compound.
An anti-human α9 integrin antibody comprising the amino acid sequences represented by SEQ ID NOS:1, 3, and 5 as CDRH1, CDRH2, and CDRH3, respectively, of the complementary determining region of the heavy chain (CDRH), and the amino acid sequences represented by SEQ ID NOS: 7, 9 and 11 as CDRL1, CDRL2, and CDRL3, respectively, of the complementary determining region of the light chain (CDRL).
A process for preparing condensation resins from at least one urea, formaldehyde, and at least one CH-acidic aldehyde, by reacting ureas of the general formula and/or in which R 1 and R 2 independently of one another are hydrogen or identical or different C 1 - C 20 alkyl radicals, A is a C 1 - C 20 alkylene radical and X is oxygen or sulfur, with formaldehyde and with a CH-acidic aldehyde of the general formula in which the radicals R 3 and R 4 independently of one another are identical or different alkyl, cycloalkyl, aryl or alkylaryl radicals, or R 3 and R 4 may together form a ring, in the temperature range between 60 and 150°C in the presence of acids, if necessary in the presence of solvent and/or diluent, which process comprises carrying out the reaction of the at least one urea, formaldehyde and the at least one CH-acidic aldehyde in a molar ratio of 1:2 to 15:2 to 15 at least partly in the presence of at least one compound selected from the group consisting of diols, diamines, amino alcohols and mercapto alcohols and has two nucleophilic groups, selected from the group consisting of hydroxyl groups (-OH), primary amino groups (-NH 2), secondary amino groups (-NH-) and thiol groups (-SH).
A two-wheeled motor vehicle having a vehicle body frame for holding a front wheel so that the front wheel is steerable, and holding a rear wheel so that the rear wheel is swingable, a fuel tank disposed at a front upper side of the vehicle body frame, a seat disposed behind the fuel tank and above the vehicle body frame, an internal combustion engine suspended between the lower side of the fuel tank and the lower side of the vehicle body frame, an air cleaner case for cleaning intake outside air and supplying the air to the internal combustion engine, a plate-like element disposed inside the air cleaner case, and a maintenance lid that constitutes a part of the air cleaner case and used when the plate-like element is mounted/dismounted, characterized in that the internal combustion engine is a four-cycle engine in which a cylinder axis is tilted forward; the air cleaner case is disposed at a rear side of a cylinder head provided to the upper portion of the cylinder and below the fuel tank and constructed by two vertically divisional cases of an upper air cleaner case formed at a clean side and a lower air cleaner case formed at a dirty side, and an air intake duct of the air cleaner case is provided below the maintenance lid; the plate-like element is disposed to be tilted to the rear and upper side in a side view of the vehicle so that a cleaning face (70A, 70B) thereof faces an up-and-down direction; and the maintenance lid is provided below the seat so as to face the seat so that the plate-like element can be pulled out when the seat is dismounted, wherein a space is formed below the seat, and wherein the space is provided so as to face the maintenance lid, and it is designed in such a size that the plate-like element can be pulled out through the space to the rear and upper side, when it is dismounted.
A washing or cleaning agent, comprising or consisting of a) at least one fatty acid tauride; b) at least one further surfactant different from a); c) at least one enzyme; and d) optionally at least one additive selected from the group consisting of builders, bleaching agents, bleach catalysts, bleach activators, electrolytes, pH adjusters, perfumes, perfume carriers, fluorescing agents, dyes, hydrotropes, complexing agents, foam inhibitors, silicone oils, soil-release polymers, graying inhibitors, shrinkage preventers, anti-wrinkle agents, antimicrobial active ingredients, solvents, germicides, fungicides, antioxidants, preservatives, corrosion inhibitors, antistats, bitterns, ironing aids, repelling and impregnating agents, skin care active ingredients, anti-swelling and anti-slip agents, plasticizing components, and UV absorbers, and mixtures thereof, characterized in that the at least one further surfactant comprises at least one anionic surfactant and the fatty acid tauride a) and the further anionic surfactant, preferably an alkyl ether sulfate, are used in a weight ratio of from 1:10 to 10:1, the at least one fatty acid tauride being contained in 0.5 to 5 wt.%, based on the total weight of the washing or cleaning agent. a) at least one fatty acid tauride; b) at least one further surfactant different from a); c) at least one enzyme; and d) optionally at least one additive selected from the group consisting of builders, bleaching agents, bleach catalysts, bleach activators, electrolytes, pH adjusters, perfumes, perfume carriers, fluorescing agents, dyes, hydrotropes, complexing agents, foam inhibitors, silicone oils, soil-release polymers, graying inhibitors, shrinkage preventers, anti-wrinkle agents, antimicrobial active ingredients, solvents, germicides, fungicides, antioxidants, preservatives, corrosion inhibitors, antistats, bitterns, ironing aids, repelling and impregnating agents, skin care active ingredients, anti-swelling and anti-slip agents, plasticizing components, and UV absorbers, and mixtures thereof, characterized in that the at least one further surfactant comprises at least one anionic surfactant and the fatty acid tauride a) and the further anionic surfactant, preferably an alkyl ether sulfate, are used in a weight ratio of from 1:10 to 10:1, the at least one fatty acid tauride being contained in 0.5 to 5 wt.%, based on the total weight of the washing or cleaning agent.
A system for inducing brainwave activity using auditory stimulation, the system comprising: an audio input (104, 202) configured to receive ambient acoustic information from an environment of a user; a modulation reference signal generator (108, 222) configured to generate a modulation reference signal based on a modulation input; a noise signal generator configured to generate a noise signal; a first audio band processor circuit (110, 210) configured to provide a primary modulated output signal based on a first frequency portion of the ambient acoustic information and on the modulation reference signal, and to provide a secondary modulated output signal based on the noise signal and on the modulation reference signal; and a mixer circuit (114, 252) configured to provide an auditory stimulation signal, wherein, when the ambient acoustic information indicates an ambient sound pressure level, SPL, meets or exceeds a specified threshold SPL, the auditory stimulation signal includes the primary modulated output signal from the first audio band processor circuit (110, 210) and a different second frequency portion of the ambient acoustic information, and when the ambient acoustic information indicates the ambient SPL is less than the specified threshold SPL, the auditory stimulation signal includes the secondary modulated output signal. an audio input (104, 202) configured to receive ambient acoustic information from an environment of a user; a modulation reference signal generator (108, 222) configured to generate a modulation reference signal based on a modulation input; a noise signal generator configured to generate a noise signal; a first audio band processor circuit (110, 210) configured to provide a primary modulated output signal based on a first frequency portion of the ambient acoustic information and on the modulation reference signal, and to provide a secondary modulated output signal based on the noise signal and on the modulation reference signal; and a mixer circuit (114, 252) configured to provide an auditory stimulation signal, wherein, when the ambient acoustic information indicates an ambient sound pressure level, SPL, meets or exceeds a specified threshold SPL, the auditory stimulation signal includes the primary modulated output signal from the first audio band processor circuit (110, 210) and a different second frequency portion of the ambient acoustic information, and when the ambient acoustic information indicates the ambient SPL is less than the specified threshold SPL, the auditory stimulation signal includes the secondary modulated output signal.
Pressure-equalization element for a housing, having a water-impermeable membrane, characterized in that a pressure-relief valve acting in two directions or a combination of two oppositely acting pressure-relief valves is arranged before or after the membrane, wherein the membrane and the pressure-relief valve(s) are combined to form a closed unit, wherein a condensation plate is arranged in the interior in the region of the inwardly acting pressure-relief valve of the closed unit and has a dripping point which is situated in the region of the outwardly acting pressure-relief valve.
A method for wireless communication performed by a user equipment, UE, the method comprising: identifying two or more network slices that collectively provide functionalities needed by the UE; determining a network slice identifier for each of the two or more network slices; and transmitting, to a network entity, a connection request comprising an indication of the determined network slice identifiers for the two or more identified network slices. identifying two or more network slices that collectively provide functionalities needed by the UE; determining a network slice identifier for each of the two or more network slices; and transmitting, to a network entity, a connection request comprising an indication of the determined network slice identifiers for the two or more identified network slices.
A driver assistance system for a motor vehicle • comprising an environment camera with a horizontal angle of view located around an optical axis and with an angular resolution (k) varying over the horizontal angle of view, - wherein the angular resolution (k) is substantially constant in a central area around the optical axis, - wherein the angular resolution (k) varies in a transition area, and - wherein the angular resolution (k) is again substantially constant in an edge area at the edge of the horizontal angle of view, • further comprising an image preparation unit which is configured to prepare the image data of the environment camera for specifying a virtual angular resolution (k'), and • an image evaluating unit which is designed to evaluate the prepared image data, characterized in that a limiting angle (α G) which divides the transition area virtually into a first transition subarea adjoining the central area and a second transition subarea adjoining the edge area is stored in a storage of the image preparation unit, wherein the angular resolution (k) in the first transition subarea is increased virtually in the course of preparation in the image preparation unit, in particular is scaled up to the angular resolution (k) in the central area, and wherein the angular resolution (k) in the second transition subarea is reduced virtually in the course of preparation in the image preparation unit, in particular is scaled down to the angular resolution (k) in the edge area. • comprising an environment camera with a horizontal angle of view located around an optical axis and with an angular resolution (k) varying over the horizontal angle of view, - wherein the angular resolution (k) is substantially constant in a central area around the optical axis, - wherein the angular resolution (k) varies in a transition area, and - wherein the angular resolution (k) is again substantially constant in an edge area at the edge of the horizontal angle of view, - wherein the angular resolution (k) is substantially constant in a central area around the optical axis, - wherein the angular resolution (k) varies in a transition area, and - wherein the angular resolution (k) is again substantially constant in an edge area at the edge of the horizontal angle of view, • further comprising an image preparation unit which is configured to prepare the image data of the environment camera for specifying a virtual angular resolution (k'), and • an image evaluating unit which is designed to evaluate the prepared image data,
A method for producing acetic acid, said method comprising: (a) reacting methanol and carbon monoxide in the presence of a carbonylation catalyst, a catalyst stabilizer, methyl iodide, water, and methyl acetate to produce a reaction mixture comprising acetic acid, water, methyl acetate, methyl Iodide, the catalyst, the catalyst stabilizer, and aldehydes; (b) flashing at least a portion of the reaction mixture to produce a vapor stream comprising acetic acid, water, methyl acetate, methyl iodide, and aldehydes and a liquid stream comprising the catalyst and the catalyst stabilizer; (c) distilling the vapor stream to form an overhead stream comprising methyl iodide, water, acetic acid, methyl acetate, and aldehydes, and an acetic acid stream comprising acetic acid, aldehydes, and water; (d) separating the overhead stream into a light aqueous phase comprising water and a heavy phase comprising methyl Iodide and aldehydes; (e) recycling the liquid stream and the heavy phase to step (a); wherein at least a portion of the aldehydes from the heavy phase is removed by the following steps: (i) reacting at least a portion of the heavy phase with an alcohol to form an acetal-containing stream; (ii) distilling the acetal-containing stream into a recovered methyl iodide stream and an acetal-enriched stream; (iii) recycling the recovered methyl iodide stream to step (a); (iv) hydrolyzing the acetal-enriched stream to form a hydrolysis mixture comprising the alcohol and the aldehydes; and (v) Isolating the alcohol from the hydrolysis mixture and recycling the alcohol to step (i), (a) reacting methanol and carbon monoxide in the presence of a carbonylation catalyst, a catalyst stabilizer, methyl iodide, water, and methyl acetate to produce a reaction mixture comprising acetic acid, water, methyl acetate, methyl Iodide, the catalyst, the catalyst stabilizer, and aldehydes; (b) flashing at least a portion of the reaction mixture to produce a vapor stream comprising acetic acid, water, methyl acetate, methyl iodide, and aldehydes and a liquid stream comprising the catalyst and the catalyst stabilizer; (c) distilling the vapor stream to form an overhead stream comprising methyl iodide, water, acetic acid, methyl acetate, and aldehydes, and an acetic acid stream comprising acetic acid, aldehydes, and water; (d) separating the overhead stream into a light aqueous phase comprising water and a heavy phase comprising methyl Iodide and aldehydes; (e) recycling the liquid stream and the heavy phase to step (a); (i) reacting at least a portion of the heavy phase with an alcohol to form an acetal-containing stream; (ii) distilling the acetal-containing stream into a recovered methyl iodide stream and an acetal-enriched stream; (iii) recycling the recovered methyl iodide stream to step (a); (iv) hydrolyzing the acetal-enriched stream to form a hydrolysis mixture comprising the alcohol and the aldehydes; and (v) Isolating the alcohol from the hydrolysis mixture and recycling the alcohol to step (i),
A system for configuring a delivery device of a cutting or welding apparatus, the system comprising: a determination module for determining at least one desired component of the delivery device or a value for at least one operating parameter of the cutting or welding apparatus; a mobile computing device comprising: a receiver for receiving information from the determination module including at least one of i) identification of the at least one desired component or ii) the value of the at least one operating parameter; a reader for reading an element associated with a selected component; and a processor for approving the selected component for assembly into the delivery device; characterized in that the element provides indicia of at least a life expectancy of the selected component and the processor is configured to approve the selected component for assembly into the delivery device if the indicia, including the life expectancy, matches the identification of the desired component or satisfies the value for the at least one operating parameter. a determination module for determining at least one desired component of the delivery device or a value for at least one operating parameter of the cutting or welding apparatus; a mobile computing device comprising: a receiver for receiving information from the determination module including at least one of i) identification of the at least one desired component or ii) the value of the at least one operating parameter; a reader for reading an element associated with a selected component; and a processor for approving the selected component for assembly into the delivery device; characterized in that the element provides indicia of at least a life expectancy of the selected component and the processor is configured to approve the selected component for assembly into the delivery device if the indicia, including the life expectancy, matches the identification of the desired component or satisfies the value for the at least one operating parameter. a receiver for receiving information from the determination module including at least one of i) identification of the at least one desired component or ii) the value of the at least one operating parameter; a reader for reading an element associated with a selected component; and a processor for approving the selected component for assembly into the delivery device; characterized in that the element provides indicia of at least a life expectancy of the selected component and the processor is configured to approve the selected component for assembly into the delivery device if the indicia, including the life expectancy, matches the identification of the desired component or satisfies the value for the at least one operating parameter.
A vehicle that leans into turns with an attitude leaning to the inner side of a curve, the vehicle comprising: main headlight light sources being arranged at both left and right sides with respect to a width direction of the vehicle and being configured to illuminate an area ahead in front of the vehicle, and a sub headlight unit (13L, 13R) comprising a right sub headlight light source (13Ra, 13Rb, 13Rc) that illuminates an area ahead and to the right of the vehicle and a left sub headlight light source (13La, 13Lb, 13Lc) that illuminates an area ahead and to the left of the vehicle, wherein the right sub headlight light source (13Ra, 13Rb, 13Rc) and the left sub headlight light source (13La, 13Lb, 13Lc) are configured such that the sub headlight light source that illuminates the same side as the side to which the vehicle is leaning is turned on in accordance with an increase in the lean angleof the vehicle, characterized in that the right sub headlight light source (13Ra, 13Rb, 13Rc) and the left sub headlight light source (13La, 13Lb, 13Lc) being arranged between the main headlight light sources to be closer to the center of the vehicle with respect to the width direction of the vehicle than the main headlight light sources. main headlight light sources being arranged at both left and right sides with respect to a width direction of the vehicle and being configured to illuminate an area ahead in front of the vehicle, and a sub headlight unit (13L, 13R) comprising a right sub headlight light source (13Ra, 13Rb, 13Rc) that illuminates an area ahead and to the right of the vehicle and a left sub headlight light source (13La, 13Lb, 13Lc) that illuminates an area ahead and to the left of the vehicle, wherein the right sub headlight light source (13Ra, 13Rb, 13Rc) and the left sub headlight light source (13La, 13Lb, 13Lc) are configured such that the sub headlight light source that illuminates the same side as the side to which the vehicle is leaning is turned on in accordance with an increase in the lean angleof the vehicle, characterized in that the right sub headlight light source (13Ra, 13Rb, 13Rc) and the left sub headlight light source (13La, 13Lb, 13Lc) being arranged between the main headlight light sources to be closer to the center of the vehicle with respect to the width direction of the vehicle than the main headlight light sources.
Vehicle with an at least partially electric drive which includes a traction battery, the traction battery comprising a storage unit consisting of a plurality of, in particular, electrochemical or galvanic storage cells, said storage cells being connected by electrically conductive contact elements to current supply leads of the vehicle, and the traction battery comprising a deformation region which can be deformed over a deformation distance (a) in the event of a crash, characterised in that the vehicle comprises at least one pre-defined deformation zone (I, II) which acts to absorb energy in the event of a crash (A, B) and in which the deformation region of the traction battery is arranged, and at least one pre-defined zone of high component strength which remains substantially undeformed in the event of a crash (A, B), and in that the contact elements of the traction battery are arranged in the zone of high component strength of the vehicle, and in that the storage unit forms the deformation region of the traction battery which is deformable in the event of a crash.
A power control unit for high-frequency dielectric heating for controlling an inverter circuit for rectifying voltage of an AC power supply, modulating the on time of high frequency switching of a switching transistor, and converting into high frequency power, said power control unit for high-frequency dielectric heating comprising: an input current detection section (71, 72; 85, 86) for detecting input current from the AC power supply to the inverter circuit and outputting input current waveform information; and a conversion section for converting the input current waveform information into a drive signal of the switching transistor of the inverter circuit so that instantaneous fluctuation of the input current waveform information is suppressed; characterized in that said input current detection section (71, 72; 85, 86) comprising a shunt resistor and an amplification circuit for amplifying the voltage across the shunt resistor, and the amplification circuit includes a filter circuit for attenuating the high-order frequency portion of the AC power supply and the high-frequency portion of high-frequency switching frequency. an input current detection section (71, 72; 85, 86) for detecting input current from the AC power supply to the inverter circuit and outputting input current waveform information; and a conversion section for converting the input current waveform information into a drive signal of the switching transistor of the inverter circuit so that instantaneous fluctuation of the input current waveform information is suppressed;