A process for producing a pharmaceutical composition comprising: (a) spraying a mixture comprising a drug, an excipient and a solvent to form at least partially non-crystalline drug-containing particles, wherein said drug-containing particles contain less than 10 wt% of said solvent and (b) drying said drug-containing particles by (i) introducing said particles into a chamber; (ii) introducing into said chamber a volatile mobility-enhancing agent that is different from said solvent; (iii) introducing a stripping gas into said chamber; (iv) exposing said particles in said chamber to said mobility enhancing agent and said flow of stripping gas; and (v) removing said stripping gas and said mobility-enhancing agent from said chamber along with at least a portion of said solvent wherein the amount of mobility-enhancing agent present in said chamber is such that during drying said particles have a glass transition temperature that is less than the glass transition temperature of the particles in the absence of said mobility-enhancing agent, but greater than the temperature at which said particles are dried; wherein said volatile mobility-enhancing agent is present in said chamber at a partial pressure of at least 0.02 atm. (a) spraying a mixture comprising a drug, an excipient and a solvent to form at least partially non-crystalline drug-containing particles, wherein said drug-containing particles contain less than 10 wt% of said solvent and (b) drying said drug-containing particles by (i) introducing said particles into a chamber; (ii) introducing into said chamber a volatile mobility-enhancing agent that is different from said solvent; (iii) introducing a stripping gas into said chamber; (iv) exposing said particles in said chamber to said mobility enhancing agent and said flow of stripping gas; and (v) removing said stripping gas and said mobility-enhancing agent from said chamber along with at least a portion of said solvent wherein the amount of mobility-enhancing agent present in said chamber is such that during drying said particles have a glass transition temperature that is less than the glass transition temperature of the particles in the absence of said mobility-enhancing agent, but greater than the temperature at which said particles are dried; wherein said volatile mobility-enhancing agent is present in said chamber at a partial pressure of at least 0.02 atm. (i) introducing said particles into a chamber; (ii) introducing into said chamber a volatile mobility-enhancing agent that is different from said solvent; (iii) introducing a stripping gas into said chamber; (iv) exposing said particles in said chamber to said mobility enhancing agent and said flow of stripping gas; and (v) removing said stripping gas and said mobility-enhancing agent from said chamber along with at least a portion of said solvent wherein the amount of mobility-enhancing agent present in said chamber is such that during drying said particles have a glass transition temperature that is less than the glass transition temperature of the particles in the absence of said mobility-enhancing agent, but greater than the temperature at which said particles are dried; wherein said volatile mobility-enhancing agent is present in said chamber at a partial pressure of at least 0.02 atm.