A medical device detachment system (300,400,500,600,700,900,1000) for placement of a medical implant in a patient's vasculature, the system (300,400, 500,600,700,900,1000) comprising: a housing (302,402,502,602,1008) configured to receive a proximal end of an elongate delivery member and a proximal end of an elongate core member slidably disposed within the delivery member; a grasping mechanism disposed within the housing (302,402,502,602, 1008) and configured to grasp a portion of the core member in response to receiving an input signal from a user, the grasping mechanism being moveable from a first position within the housing (302,402,502,602,1008) to a second position within the housing (302,402,502,602,1008); a user input mechanism (303,406,508,603,708,800,904) configured to receive the input signal from the user and permit movement of the grasping mechanism to grasp the proximal end of the core member; a first sensor (506,612,706,912,1003) configured to provide an output signal confirming placement of the proximal end of the core member on the grasping mechanism at a determined position of the grasping mechanism within the housing (302,402,502,602,1008); a second sensor (514,618,719,1005) positioned to detect when the grasping mechanism is at the second position, and configured to provide an output signal indicative of the position of the grasping mechanism at the second position; and an indicator (330,408,516,616,716) connected to the first and second sensors (506,514,612,618,706,719,912,1003,1005) and configured to receive one or more output signals from the first and second sensors (506,514,612,618,706,719,912,1003, 1005) and to provide corresponding indications to a user when one or more output signals are received from the first or second proximity sensors (506,514,612,618,706,719,912,1003,1005). a housing (302,402,502,602,1008) configured to receive a proximal end of an elongate delivery member and a proximal end of an elongate core member slidably disposed within the delivery member; a grasping mechanism disposed within the housing (302,402,502,602, 1008) and configured to grasp a portion of the core member in response to receiving an input signal from a user, the grasping mechanism being moveable from a first position within the housing (302,402,502,602,1008) to a second position within the housing (302,402,502,602,1008); a user input mechanism (303,406,508,603,708,800,904) configured to receive the input signal from the user and permit movement of the grasping mechanism to grasp the proximal end of the core member; a first sensor (506,612,706,912,1003) configured to provide an output signal confirming placement of the proximal end of the core member on the grasping mechanism at a determined position of the grasping mechanism within the housing (302,402,502,602,1008); a second sensor (514,618,719,1005) positioned to detect when the grasping mechanism is at the second position, and configured to provide an output signal indicative of the position of the grasping mechanism at the second position; and an indicator (330,408,516,616,716) connected to the first and second sensors (506,514,612,618,706,719,912,1003,1005) and configured to receive one or more output signals from the first and second sensors (506,514,612,618,706,719,912,1003, 1005) and to provide corresponding indications to a user when one or more output signals are received from the first or second proximity sensors (506,514,612,618,706,719,912,1003,1005).