mhurhangee/ep-ind-claims huggingface dataset:
Mixture comprising one or more compounds of formula and/or one or more salts thereof, wherein R1 is an aliphatic substituent with no or one, two, three or more than three hydroxy groups, wherein the total number of carbon atoms in the aliphatic substituent R1 is not more than 15, and wherein the aliphatic substituent - is saturated or unsaturated and - is branched or unbranched and - is acyclic or cyclic, with the proviso that the compound(s) of formula or the salt(s) thereof, in case that R1 is an aliphatic substituent with no hydroxy group, is/are selected from the group consisting of the compounds cyclohexyl cannabidivarinolate and hexyl cannabidivarinolate and salts thereof, wherein in the mixture the molar ratio of the total amount of compounds of formula and their salts to the amount of compound of formula (cannabidivarin, CBDV) is greater than 1:1, and simultaneously the molar ratio of the total amount of compounds of formula and their salts to the amount of the compound of formula ((-)-trans-methyl cannabidivarinolate) is greater than 1:1. - is saturated or unsaturated and - is branched or unbranched and - is acyclic or cyclic,
A compound of Formula (Ia) or a pharmaceutically acceptable salt thereof, wherein: A is a 4 to 7 membered monocyclic heterocyclyl saturated or partially unsaturated and optionally substituted with 1 to 5 R 3 groups; each R 3 is independently selected from the group consisting of C 1-4 alkyl, halogen and oxo; or two R 3 connected to the same or adjacent carbon atoms form a spiro or fused C 3-6 cycloalkyl or 4 to 6 membered heterocyclyl ring; A' is selected from the group consisting of C 3-7 monocyclic cycloalkyl and 4 to 7 membered monocyclic heterocyclyl; wherein each C 3-7 monocyclic cycloalkyl and 4 to 7 membered monocyclic heterocyclyl is optionally substituted with 1 to 5 R 4 groups; each R 4 is independently selected from the group consisting of C 1-4 alkyl, halogen and oxo; or two R 4 connected to the same or adjacent carbon atoms form a spiro or fused C 3-6 cycloalkyl or 4 to 6 membered heterocyclyl ring; R 1 is phenyl optionally substituted with 1 to 5 R 5 groups; each R 5 is independently selected from the group consisting of halogen and C 1-3 alkyl; and R 2 is selected from the group consisting of H, C 1-3 haloalkyl and C 1-4 alkyl. A is a 4 to 7 membered monocyclic heterocyclyl saturated or partially unsaturated and optionally substituted with 1 to 5 R 3 groups; each R 3 is independently selected from the group consisting of C 1-4 alkyl, halogen and oxo; or two R 3 connected to the same or adjacent carbon atoms form a spiro or fused C 3-6 cycloalkyl or 4 to 6 membered heterocyclyl ring; A' is selected from the group consisting of C 3-7 monocyclic cycloalkyl and 4 to 7 membered monocyclic heterocyclyl; wherein each C 3-7 monocyclic cycloalkyl and 4 to 7 membered monocyclic heterocyclyl is optionally substituted with 1 to 5 R 4 groups; each R 4 is independently selected from the group consisting of C 1-4 alkyl, halogen and oxo; or two R 4 connected to the same or adjacent carbon atoms form a spiro or fused C 3-6 cycloalkyl or 4 to 6 membered heterocyclyl ring; R 1 is phenyl optionally substituted with 1 to 5 R 5 groups; each R 5 is independently selected from the group consisting of halogen and C 1-3 alkyl; and R 2 is selected from the group consisting of H, C 1-3 haloalkyl and C 1-4 alkyl.
Gas turbine comprising: a combustion chamber limited by at least one wall having an inner surface; a further chamber; an acoustic damper comprising a neck and a damping volume, wherein: the neck comprises a mouth in the inner surface of the wall of the combustion chamber; the damping volume is connected via a bore to the further chamber; and a flow of grazing gas flows inside the combustion chamber parallel to the inner surface over the mouth; wherein the gas turbine comprises a further bore connecting the chamber and the further chamber and having at least one opening (27, 35) in the inner surface of the wall adjacent to the mouth of the neck, upstream of the mouth with respect to the flow of grazing gas, characterised in that the further bore is configured so that a flow of sealing gas is supplied through the at least one opening (27, 35) for sealing, enters the combustion chamber perpendicularly to the flow of grazing gas with a velocity higher than a velocity of the flow of grazing gas and deflects the flow of grazing gas away from the mouth of the neck. a combustion chamber limited by at least one wall having an inner surface; a further chamber; an acoustic damper comprising a neck and a damping volume, wherein: the neck comprises a mouth in the inner surface of the wall of the combustion chamber; the damping volume is connected via a bore to the further chamber; and a flow of grazing gas flows inside the combustion chamber parallel to the inner surface over the mouth; wherein the gas turbine comprises a further bore connecting the chamber and the further chamber and having at least one opening (27, 35) in the inner surface of the wall adjacent to the mouth of the neck, upstream of the mouth with respect to the flow of grazing gas, characterised in that the further bore is configured so that a flow of sealing gas is supplied through the at least one opening (27, 35) for sealing, enters the combustion chamber perpendicularly to the flow of grazing gas with a velocity higher than a velocity of the flow of grazing gas and deflects the flow of grazing gas away from the mouth of the neck. the neck comprises a mouth in the inner surface of the wall of the combustion chamber; the damping volume is connected via a bore to the further chamber; and a flow of grazing gas flows inside the combustion chamber parallel to the inner surface over the mouth;
A computer-implemented method for evaluating stacked seismic trace data, the method comprising: isolating (10, 12) a portion of each of a plurality of seismic traces representing physical properties of a subsurface region by analyzing instantaneous frequency data for the seismic traces; the method being characterized in calculating simple sweet values for the seismic traces based on IA/ 1/2, where IF represents one or more instantaneous frequency attributes and IA represents one or more instantaneous amplitude attributes; blending the calculated simple sweet values with instantaneous phase information for the seismic traces; calculating simple tuned values for the seismic traces based on IA*IF; blending the calculated simple tuned values with instantaneous phase information for the seismic traces; and cross-plotting (18, 20) the blended simple sweet and instantaneous phase information with the blended simple tuned and instantaneous phase information to identify high probability zones that are likely to comprise hydrocarbon resources. isolating (10, 12) a portion of each of a plurality of seismic traces representing physical properties of a subsurface region by analyzing instantaneous frequency data for the seismic traces; the method being characterized in calculating simple sweet values for the seismic traces based on IA/ 1/2, where IF represents one or more instantaneous frequency attributes and IA represents one or more instantaneous amplitude attributes; blending the calculated simple sweet values with instantaneous phase information for the seismic traces; calculating simple tuned values for the seismic traces based on IA*IF; blending the calculated simple tuned values with instantaneous phase information for the seismic traces; and cross-plotting (18, 20) the blended simple sweet and instantaneous phase information with the blended simple tuned and instantaneous phase information to identify high probability zones that are likely to comprise hydrocarbon resources.
One or more computer-storage media having computer executable instructions embodied thereon that when executed by a computing device perform a method of playing a video game using three-dimensional image data as a control input in a server based gaming environment, the method comprising: receiving (71 0), at a game client, three-dimensional image data as a video game control input; process, at the game client, the three-dimensional image data input to generate a basic control input; communicate through a communications network the basic control input from the game client over the computer network to a game server on which the video game is running; process, at the game client, part of the three-dimensional image data input to generate a client-rendered video game feature; receive, through the communications network over the computer network at the game client, a server-rendered video game image from the game server on which the video game is running, the server-rendered video game image being generated in response to a change in game state caused by the basic control input; generating, at the game client, a composite video game image by combining the server-rendered video game image generated by the game server in response to the three-dimensional image data input with the client-rendered video game feature; and output the rendered composite video to a display device; wherein a roundtrip duration is processed to determine if the rendered image is generated at the client or server based on a latency sensitivity rating. receiving (71 0), at a game client, three-dimensional image data as a video game control input; process, at the game client, the three-dimensional image data input to generate a basic control input; communicate through a communications network the basic control input from the game client over the computer network to a game server on which the video game is running; process, at the game client, part of the three-dimensional image data input to generate a client-rendered video game feature; receive, through the communications network over the computer network at the game client, a server-rendered video game image from the game server on which the video game is running, the server-rendered video game image being generated in response to a change in game state caused by the basic control input; generating, at the game client, a composite video game image by combining the server-rendered video game image generated by the game server in response to the three-dimensional image data input with the client-rendered video game feature; and output the rendered composite video to a display device; wherein a roundtrip duration is processed to determine if the rendered image is generated at the client or server based on a latency sensitivity rating.
A hand-held portable printer comprising: a housing having an upper main body and a handle extending therefrom; a rotatably driven platen roller supported in the main body of the housing; a supply roll holder that holds a supply roll of media in the main body of the housing; a circuit board including an electrical ground; and a print module assembly including a printhead that selectively prints on media routed between the printhead and the platen roller from the supply roll held by the supply roll holder, said print module assembly being attached to the upper main body of the housing such that the print module assembly is movable between a closed operational position in which the printhead is proximate the platen roller and an open loading position in which the printhead is spaced apart from the platen roller; characterised in that the printer further comprises: a first electrically conductive ground path extending from the printhead to the electrical ground on the circuit board, said circuit board being housed outside the movable print module assembly, and said first electrically conductive ground path remaining unbroken regardless of the position of the print module assembly. a housing having an upper main body and a handle extending therefrom; a rotatably driven platen roller supported in the main body of the housing; a supply roll holder that holds a supply roll of media in the main body of the housing; a circuit board including an electrical ground; and a print module assembly including a printhead that selectively prints on media routed between the printhead and the platen roller from the supply roll held by the supply roll holder, said print module assembly being attached to the upper main body of the housing such that the print module assembly is movable between a closed operational position in which the printhead is proximate the platen roller and an open loading position in which the printhead is spaced apart from the platen roller; characterised in that the printer further comprises: a first electrically conductive ground path extending from the printhead to the electrical ground on the circuit board, said circuit board being housed outside the movable print module assembly, and said first electrically conductive ground path remaining unbroken regardless of the position of the print module assembly. a first electrically conductive ground path extending from the printhead to the electrical ground on the circuit board, said circuit board being housed outside the movable print module assembly, and said first electrically conductive ground path remaining unbroken regardless of the position of the print module assembly.
Method for monitoring a state of an electrical line, in which a data communication is carried out over the electrical line, wherein parameters for the data communication are determined, and a state of the electrical line is estimated from the parameters, wherein the parameters comprise at least one of the parameters of data transmission rate, bit error rate, signal-to-noise ratio, phase angle, frame length, modulation method and channel encoding, characterized in that the state is indicated by at least one of the state parameters of partial discharge status, sag of a line, snow loading and/or ice loading on the line, temperature of the line, wind loading of the line, wherein disturbances are recognized in a received signal during data communication, from which partial discharges are recognized through low-pass filtering and correlation of the disturbances with the phase and the maximum amplitude and/or the polarity of the received signal.
An in vitro method for determining the likelihood for a patient affected with a tumor to respond to a treatment with a pro-apoptotic peptide able to disrupt interaction between caspase 9 and PP2A, which method comprises determining expression level of at least each of VIM, MK167, TCF7L2, NEK2, BIRC5, MCL1, and PLK1 genes, in a biological sample of said patient.
A method of separating a saccharide from an aqueous product solution of a cellulose hydrolysis process, wherein the aqueous product solution comprises a saccharide and a cellulose swelling agent, and the cellulose swelling agent is zinc chloride, magnesium chloride or a combination thereof, and the method comprises the following steps in the given order: (a) adding a first tertiary amine and an optional first organic solvent to the aqueous product solution to provide a mixture; (b) performing a solid-liquid separation to obtain a solution from the mixture; and (c) performing a liquid-liquid extraction by adding a second tertiary amine and a second organic solvent to the solution, and then removing the organic phase and collecting the aqueous phase, wherein the first tertiary amine and the second tertiary amine are the same or different, and the first organic solvent and the second organic solvent are the same or different. (a) adding a first tertiary amine and an optional first organic solvent to the aqueous product solution to provide a mixture; (b) performing a solid-liquid separation to obtain a solution from the mixture; and (c) performing a liquid-liquid extraction by adding a second tertiary amine and a second organic solvent to the solution, and then removing the organic phase and collecting the aqueous phase, wherein the first tertiary amine and the second tertiary amine are the same or different, and the first organic solvent and the second organic solvent are the same or different.
A product comprising a sweet ingestible composition comprising Reb B and at least one sweetener, selected from the group consisting of Mogroside V, sucralose and erythritol, wherein said at least one sweetener is present in the product at a concentration above 2% sucrose equivalent sweetness, and Reb B having a purity of at least 95% wt/wt on anhydrous basis is present at a concentration from 10 to 300 ppm.
A method of testing temperature sensors of refrigerated cargo spaces, comprising: removably installing a wireless temperature sensor in proximity of a cargo space temperature sensor of a refrigerated cargo space; receiving, at a data processing device, temperature data from both the cargo space temperature sensor and the wireless temperature sensor; calculating a temperature difference between the temperature measured by the cargo space temperature sensor and the wireless temperature sensor; and calibrating or replacing the cargo space temperature sensor if the temperature difference exceeds a threshold difference. removably installing a wireless temperature sensor in proximity of a cargo space temperature sensor of a refrigerated cargo space; receiving, at a data processing device, temperature data from both the cargo space temperature sensor and the wireless temperature sensor; calculating a temperature difference between the temperature measured by the cargo space temperature sensor and the wireless temperature sensor; and calibrating or replacing the cargo space temperature sensor if the temperature difference exceeds a threshold difference.
Electrical contact element which is composed of solid material and which is designed as a socket contact and which has a plug-in region and a connection region, wherein the connection region is designed as a crimp connection for making contact with an electrical conductor, wherein wedge-shaped slots are introduced into the contact region, as a result of which spring arms are formed, • characterized in that the connection region is in the form of a hollow cylinder which contains a slot in the axial direction, • the length of the axial slot of the hollow cylinder is more than half of the length of the hollow cylinder, • in addition to the axial slot, the hollow cylinder has at least one second slot which is formed substantially at a 90° angle to the axial slot. • characterized in that the connection region is in the form of a hollow cylinder which contains a slot in the axial direction, • the length of the axial slot of the hollow cylinder is more than half of the length of the hollow cylinder, • in addition to the axial slot, the hollow cylinder has at least one second slot which is formed substantially at a 90° angle to the axial slot.
A method of deforming a component cast from a titanium alloy, such that each of the volume of the component of the component, the density of the component, and the surface area of the component, remains substantially constant throughout the deformation process, the method comprising the steps of: heating the component to a plastic temperature such that it becomes plastically deformable; and applying a force in a predetermined direction to at least one region of the component while the component is at the plastic temperature, the force being applied by a deformation member configured to engage with at least a part of the surface of the component, the deformation member comprising a substantially rigid body, the rigid body being provided with location features for engagement with the surface of the component, the location features defining the desired component geometric shape, and the component being provided with location pads for engagement with the location features of the rigid body, the force being communicated from the deformation member to the location pads and reacted at the location pads by a base member to thereby plastically deform the component to a desired geometric shape and reducing the temperature of the component to below the plastic temperature, heating the component to a plastic temperature such that it becomes plastically deformable; and applying a force in a predetermined direction to at least one region of the component while the component is at the plastic temperature, the force being applied by a deformation member configured to engage with at least a part of the surface of the component, the deformation member comprising a substantially rigid body, the rigid body being provided with location features for engagement with the surface of the component, the location features defining the desired component geometric shape, and the component being provided with location pads for engagement with the location features of the rigid body, the force being communicated from the deformation member to the location pads and reacted at the location pads by a base member to thereby plastically deform the component to a desired geometric shape and reducing the temperature of the component to below the plastic temperature,
A liposomal anti-infective for use in treating or ameliorating a pulmonary infection in a patient wherein the anti-infective is amikacin, for pulmonary administration to the patient by inhalation, the dosing of the anti-infective is once a day or less and the lipids used to form the liposomes consist of dipalmitoyl phosphatidylcholine (DPPC) and cholesterol.
Test bench with a base frame on which a test bench drive is arranged, having a test shaft that can be driven rotationally about an axis of rotation, wherein the test shaft can be connected coaxially to a bearing shaft of a bearing unit that is mounted rotatably about the axis of rotation, wherein the bearing unit is releasably arranged in a recess, coaxial with the axis of rotation, of a bearing housing that is fixedly connected to the base frame, and the bearing shaft has, at its end projecting from the bearing housing and facing away from the test bench drive, a fastening element for the releasable attachment of a test specimen, characterized in that the coaxial recess in the bearing housing is a conical-section-shaped recess symmetrical to the axis of rotation, in which a bearing sleeve of the bearing unit is non-rotatably and releasably arranged, said bearing sleeve having an outer conical wall which, with its at least partially matching outer contour, conforms to the contour of the wall of the conical-section-shaped recess and is in contact with the wall of the conical-section-shaped recess, wherein the bearing sleeve also has a through-bearing bore coaxial with the axis of rotation, in which the bearing shaft is rotatably supported via one or multiple bearings.
The trisaccharide Gal (beta 1-3) - Gal (beta 1-4) - Glc (beta-1,3'-galactosyllactose) for use in increasing the intestinal barrier function and/or for use in the prevention and/or treatment of intestinal barrier disruption in a subject.