A method for manufacturing a personalized implantable prosthesis in a manufacturing facility, said method comprising: providing one or more images of a treatment site in a patient; creating a digital data set characterizing shape and volume of the treatment site based on the one or more images; transforming the digital data set into machining instructions; forming a mandrel using the machining instructions, wherein the mandrel has a shape that substantially matches the treatment site shape; applying a mesh to the mandrel, wherein the mesh comprises a plurality of filaments forming overlapping regions (1006d, 1008d) in every row and column of the mesh where the filaments meet, the mesh forming a tubular member with the rows extending circumferentially around the tubular member, wherein the overlapping regions in a row form an alternating pattern of overlapping regions having a first number of overlaps of the plurality of overlapping filaments and overlapping regions having a second number of overlaps different than the first number of overlaps, and wherein the first number of overlaps allows some movement of the plurality of overlapping filaments relative to one another thereby allowing the prosthesis to expand and contract, and wherein the second number of overlaps secures the plurality of overlapping filaments together to minimize their movement relative to one another during compression or tension; and heat treating the mesh while the mesh is disposed over the mandrel so that the mesh is biased to return to a shape matching the shape of the treatment site thereby forming the personalized implantable prosthesis, the personalized implantable prosthesis having a contracted configuration and an expanded configuration, wherein the personalized implantable prosthesis is adapted to be delivered to the treatment site in the contracted configuration, and wherein the personalized implantable prosthesis is biased to return to the expanded configuration, the expanded configuration having a shape substantially matching the treatment site shape. providing one or more images of a treatment site in a patient; creating a digital data set characterizing shape and volume of the treatment site based on the one or more images; transforming the digital data set into machining instructions; forming a mandrel using the machining instructions, wherein the mandrel has a shape that substantially matches the treatment site shape; applying a mesh to the mandrel, wherein the mesh comprises a plurality of filaments forming overlapping regions (1006d, 1008d) in every row and column of the mesh where the filaments meet, the mesh forming a tubular member with the rows extending circumferentially around the tubular member, wherein the overlapping regions in a row form an alternating pattern of overlapping regions having a first number of overlaps of the plurality of overlapping filaments and overlapping regions having a second number of overlaps different than the first number of overlaps, and wherein the first number of overlaps allows some movement of the plurality of overlapping filaments relative to one another thereby allowing the prosthesis to expand and contract, and wherein the second number of overlaps secures the plurality of overlapping filaments together to minimize their movement relative to one another during compression or tension; and heat treating the mesh while the mesh is disposed over the mandrel so that the mesh is biased to return to a shape matching the shape of the treatment site thereby forming the personalized implantable prosthesis, the personalized implantable prosthesis having a contracted configuration and an expanded configuration, wherein the personalized implantable prosthesis is adapted to be delivered to the treatment site in the contracted configuration, and wherein the personalized implantable prosthesis is biased to return to the expanded configuration, the expanded configuration having a shape substantially matching the treatment site shape.