mhurhangee/ep-ind-claims huggingface dataset:
A method of analyzing a maternal plasma sample of a pregnant woman, the sample including cell-free DNA fragments originating from maternal cells and from fetal cells, the method comprising: for each of a plurality of DNA fragments from the plasma sample: receiving one or more sequence reads obtained from a sequencing of the DNA fragment, the one or more sequence reads including both ends of the DNA fragment; aligning the one or more sequence reads to a reference genome to obtain aligned locations for both ends of the DNA fragment; and using the aligned locations to determine a size of the DNA fragment; for each size of a plurality of sizes: determining an amount of a set of the plurality of DNA fragments from the plasma sample corresponding to the size, using the sizes determined from the aligned locations for the plurality of DNA fragments; calculating a first value of a first parameter based on the amounts of DNA fragments at multiple sizes, the first parameter providing a statistical measure of a size profile of DNA fragments in the plasma sample; comparing the first value to a calibration value; and estimating a fractional concentration of fetal DNA in the plasma sample based on the comparison. for each of a plurality of DNA fragments from the plasma sample: receiving one or more sequence reads obtained from a sequencing of the DNA fragment, the one or more sequence reads including both ends of the DNA fragment; aligning the one or more sequence reads to a reference genome to obtain aligned locations for both ends of the DNA fragment; and using the aligned locations to determine a size of the DNA fragment; receiving one or more sequence reads obtained from a sequencing of the DNA fragment, the one or more sequence reads including both ends of the DNA fragment; aligning the one or more sequence reads to a reference genome to obtain aligned locations for both ends of the DNA fragment; and using the aligned locations to determine a size of the DNA fragment; for each size of a plurality of sizes: determining an amount of a set of the plurality of DNA fragments from the plasma sample corresponding to the size, using the sizes determined from the aligned locations for the plurality of DNA fragments; determining an amount of a set of the plurality of DNA fragments from the plasma sample corresponding to the size, using the sizes determined from the aligned locations for the plurality of DNA fragments; calculating a first value of a first parameter based on the amounts of DNA fragments at multiple sizes, the first parameter providing a statistical measure of a size profile of DNA fragments in the plasma sample; comparing the first value to a calibration value; and estimating a fractional concentration of fetal DNA in the plasma sample based on the comparison.
A system for planning and/or adjusting and/or providing a neuromodulation therapy for use in a method of treatment of a patient suffering from stroke, cerebral palsy, multiple sclerosis, autonomic failure, autonomic neuropathy and/or cancer of the neurological tissue, the system comprising: - at least one neuromodulation means configured to provide neuromodulation at least partially by means of neurostimulation; - at least one neuromodulation controller configured to control the neuromodulation means, wherein the neuromodulation controller is further configured to control the neuromodulation means at the beginning of a neuromodulation action including neurostimulation that the neurostimulation comprises a starting sequence and/or at the end of a neuromodulation action including neurostimulation that the neurostimulation comprises an ending sequence, and wherein the neuromodulation is planned to be provided and/or provided to a spatial area of a patient, characterized in that the spatial area during the starting sequence and/or ending sequence is limited compared to the spatial area during the stimulation after the starting sequence and/or before the ending sequence. - at least one neuromodulation means configured to provide neuromodulation at least partially by means of neurostimulation; - at least one neuromodulation controller configured to control the neuromodulation means, wherein the neuromodulation controller is further configured to control the neuromodulation means at the beginning of a neuromodulation action including neurostimulation that the neurostimulation comprises a starting sequence and/or at the end of a neuromodulation action including neurostimulation that the neurostimulation comprises an ending sequence, and wherein the neuromodulation is planned to be provided and/or provided to a spatial area of a patient, characterized in that the spatial area during the starting sequence and/or ending sequence is limited compared to the spatial area during the stimulation after the starting sequence and/or before the ending sequence.
A T-tail joint assembly for a T-tail empennage, the T-tail joint assembly comprising: a plurality of lower rib chord members, each having a first base member, a first fin projecting from a first surface of the first base member, notches in the first fin proximate to ends of the first base member, and attachment members projecting from a second surface of the first base member that opposes the first surface; a plurality of upper rib chord members, each having a second base member, a second fin projecting from a surface of the second base member, and notches in the second fin proximate to ends of the second base member; a plurality of spar fittings disposed between the upper rib chord members and the lower rib chord members, wherein the spar fittings engage the notches in the first fin of the lower rib chord members and the notches in the second fin of the upper rib chord members; and a plurality of spar chords coupled to and separating pairs of the upper rib chord members and the lower rib chord members, wherein the plurality of spar chords is proximate to ends of the first base member and the second base member. a plurality of lower rib chord members, each having a first base member, a first fin projecting from a first surface of the first base member, notches in the first fin proximate to ends of the first base member, and attachment members projecting from a second surface of the first base member that opposes the first surface; a plurality of upper rib chord members, each having a second base member, a second fin projecting from a surface of the second base member, and notches in the second fin proximate to ends of the second base member; a plurality of spar fittings disposed between the upper rib chord members and the lower rib chord members, wherein the spar fittings engage the notches in the first fin of the lower rib chord members and the notches in the second fin of the upper rib chord members; and a plurality of spar chords coupled to and separating pairs of the upper rib chord members and the lower rib chord members, wherein the plurality of spar chords is proximate to ends of the first base member and the second base member.
A computer-implemented method comprising: receiving operations data from a plurality of networked agents; storing the operations data in a historical data store; building a machine learning model using the historical data store and a dependency graph; receiving an indication of a user experience problem, wherein the user experience problem is associated with observed operations data (410, 415, 420, 425); converting the observed operations data (410, 415, 420, 425) into a set of observed features and an observed outcome that corresponds to the user experience problem; generating, based on the set of observed features, a first predicted outcom and a set of candidate causes of the user experience according to the machine learning model; determining that the observed outcome is within range of the first predicted outcome; and identifying the set of candidate causes of the user experience problem when the observed outcome is within range of the first predicted outcome. receiving operations data from a plurality of networked agents; storing the operations data in a historical data store; building a machine learning model using the historical data store and a dependency graph; receiving an indication of a user experience problem, wherein the user experience problem is associated with observed operations data (410, 415, 420, 425); converting the observed operations data (410, 415, 420, 425) into a set of observed features and an observed outcome that corresponds to the user experience problem; generating, based on the set of observed features, a first predicted outcom and a set of candidate causes of the user experience according to the machine learning model; determining that the observed outcome is within range of the first predicted outcome; and identifying the set of candidate causes of the user experience problem when the observed outcome is within range of the first predicted outcome.
A wavelength conversion device, comprising: a light source that emits light having a wavelength that is predetermined, the wavelength being included in a wavelength range from ultraviolet light to visible light; a phosphor layer that converts the wavelength of light from the light source which is incident on an incidence face of the phosphor layer; and an optical component that is disposed between the light source and the phosphor layer, and projects light emitted by the light source onto the incidence face of the phosphor layer in a ring shape, characterized in that the optical component projects the light emitted by the light source onto the incidence face, in a ring shape centered on an optical axis of the light source and having a diameter less than or equal to a diameter of the light emitted by the light source. a light source that emits light having a wavelength that is predetermined, the wavelength being included in a wavelength range from ultraviolet light to visible light; a phosphor layer that converts the wavelength of light from the light source which is incident on an incidence face of the phosphor layer; and an optical component that is disposed between the light source and the phosphor layer, and projects light emitted by the light source onto the incidence face of the phosphor layer in a ring shape, characterized in that the optical component projects the light emitted by the light source onto the incidence face, in a ring shape centered on an optical axis of the light source and having a diameter less than or equal to a diameter of the light emitted by the light source.
Metal heat exchanger pipe, comprising a pipe wall and ribs which extend round at the pipe outer side and which have a rib base, rib flanks and a rib tip and a primary groove which is formed between the ribs, wherein the rib base protrudes substantially radially from the pipe wall, and the rib flanks are provided along the primary groove with additional structural elements which are spaced apart from each other and which are constructed as material projections which are formed from the material of the rib flank and which are arranged laterally on the rib flank, characterised in that - the material projections are deformed in such a manner that they touch the pipe wall in the region of the primary groove so that local cavities are formed, and - in that the cavities have openings (51, 52) in the peripheral direction of the ribs. - the material projections are deformed in such a manner that they touch the pipe wall in the region of the primary groove so that local cavities are formed, and - in that the cavities have openings (51, 52) in the peripheral direction of the ribs.
A sealing and mounting tape arrangement (100, 100a-100h) for setting an installation object, preferably a shower or bathtub (3, 3a-3h), against at least one connecting wall (61, 6a-6j) or at least one connecting floor, with a sealing and mounting base body or carrier material (1, 1a-1h), which forms a first, lower region (4, 4a-4h) with an installation object- or tub-side adhesive surface (9a, 21a, 21c, 21e, 21g, 21i, 21k, 21m) toward a downward flange (2, 2a-2h) of the installation object, preferably the shower or bathtub (3, 3a-3h), and a second, upper region (5, 5a-5h) with a wall- or floor-side adhesive surface (9b, 21b, 21d, 21f, 21h, 21j, 211, 21n) toward the at least one connecting wall (61, 6a-6j) or the at least one connecting floor, characterized in that the sealing and mounting tape base body or the carrier material (1, 1a-1h) consists of a material that can be stretched and deformed in any directions with a stretchability in the transverse and longitudinal direction of at least 200%, preferably 500% - 1200%, further preferably about 1000%, so that the sealing and mounting tape arrangement (100, 100a-100h), once the first, lower region (4, 4a-4h) has been fastened along or around a corner of the downward flange (2, 2a-2h), the second, upper region (5, 5a-5h) can be stretched in any direction away from the installation object (3, 3a-3h) over the floor-floor corner regions or wall-floor transitions and fastened.
A device for treating an ocular pathology, comprising a ring having a proximal end intended to be in contact with a patient's eye and a distal end intended to receive ultrasound generating means, the device further comprising at least one reflector including an active concave face facing the ultrasound generating means to reflect and focus the ultrasounds generated by the generating means in a region of the patient's eye, and the ultrasound generating means comprising at least one transducer having a front face to radiate the ultrasounds, the front face of each transducer extending parallel to the axis of revolution (A-A') of the ring.
An apparatus, comprising: a crystal having an upper surface, said crystal being a pyroelectric crystal or a piezoelectric crystal; a conducting film coating the upper surface of the crystal; said crystal including a plurality of electron field emitters, the electron field emitters comprising a micrometer-scale region, the region having one or more sharp peaks or ridges; and means for controlling temperature of the crystal where said crystal is a pyroelectric crystal, or means for controlling strain on the crystal where said crystal is a piezoelectric crystal; wherein said crystal and said electron field emitters are maintained in a low pressure environment. a crystal having an upper surface, said crystal being a pyroelectric crystal or a piezoelectric crystal; a conducting film coating the upper surface of the crystal; said crystal including a plurality of electron field emitters, the electron field emitters comprising a micrometer-scale region, the region having one or more sharp peaks or ridges; and means for controlling temperature of the crystal where said crystal is a pyroelectric crystal, or means for controlling strain on the crystal where said crystal is a piezoelectric crystal; wherein said crystal and said electron field emitters are maintained in a low pressure environment.
A mobile car sheave shield for a V-shaped traction system of an elevator system, the mobile car sheave shield comprises: a static shield part suitable to be sleeved on a car sheave, wherein an opening is formed on an upper surface of the static shield part; and a dynamic shield part, wherein the dynamic shield part is arranged on the opening; the dynamic shield part comprises a shield bracket; an inner side mobile shield and an outer side mobile shield which are synchronously connected are respectively arranged on two sides of a central axis of the shield bracket from inside to outside; the outer side mobile shield and the inner side mobile shield are slidingly connected on the shield bracket; a notch is formed between the inner side mobile shield and the outer side mobile shield, and suitable to be arranged such that a traction rope runs through the notch. a static shield part suitable to be sleeved on a car sheave, wherein an opening is formed on an upper surface of the static shield part; and a dynamic shield part, wherein the dynamic shield part is arranged on the opening; the dynamic shield part comprises a shield bracket; an inner side mobile shield and an outer side mobile shield which are synchronously connected are respectively arranged on two sides of a central axis of the shield bracket from inside to outside; the outer side mobile shield and the inner side mobile shield are slidingly connected on the shield bracket; a notch is formed between the inner side mobile shield and the outer side mobile shield, and suitable to be arranged such that a traction rope runs through the notch.
An audio signal processing device configured to generate and output 2-channel audio signals suitable to be acoustically reproduced by two electro-acoustic transducer means arranged at positions close to both ears of a listener from audio signals of plural channels of two or more channels, comprising: head related transfer function convolution processing units configured to convolute head related transfer functions with the audio signals of respective channels of plural channels, which allow the listener to listen to sound so that sound images are localized at assumed virtual sound image localization positions concerning respective channels of the plural channels of two or more channels when sound is acoustically reproduced by the two electro-acoustic transducer means (SPL, SPR); and 2-channel signal generation means for generating 2-channel audio signals to be supplied to the two electro-acoustic transducer means from audio signals of plural channels from the head related transfer function convolution processing units, wherein, the head related transfer function convolution processing units are configured to convolute respective head related transfer functions concerning direct waves and plural reflected waves with the audio signals of the plural channels, and not to convolute a head related transfer function concerning direct waves from the assumed virtual image localization positions concerning a left channel and a right channel in the plural channels to both ears of the listener. head related transfer function convolution processing units configured to convolute head related transfer functions with the audio signals of respective channels of plural channels, which allow the listener to listen to sound so that sound images are localized at assumed virtual sound image localization positions concerning respective channels of the plural channels of two or more channels when sound is acoustically reproduced by the two electro-acoustic transducer means (SPL, SPR); and 2-channel signal generation means for generating 2-channel audio signals to be supplied to the two electro-acoustic transducer means from audio signals of plural channels from the head related transfer function convolution processing units, wherein, the head related transfer function convolution processing units are configured to convolute respective head related transfer functions concerning direct waves and plural reflected waves with the audio signals of the plural channels, and not to convolute a head related transfer function concerning direct waves from the assumed virtual image localization positions concerning a left channel and a right channel in the plural channels to both ears of the listener.
A coating for an ingestible material comprising: a first substrate comprising a first plurality of particles, the particles having a first dimension (d 1), wherein the particles are stacked to define a plurality of lattices that selectively diffract electromagnetic radiation and wherein each of the plurality of particles comprise a generally recognized as safe material selected from the group consisting of cross-linked polylactic acid, shellac, cellulose and cellulose derivatives. a first substrate comprising a first plurality of particles, the particles having a first dimension (d 1), wherein the particles are stacked to define a plurality of lattices that selectively diffract electromagnetic radiation and wherein each of the plurality of particles comprise a generally recognized as safe material selected from the group consisting of cross-linked polylactic acid, shellac, cellulose and cellulose derivatives.
A composition comprising: a. an aqueous colloidal dispersion comprising hydroxypropyl methyl cellulose acetate succinate (HPMCAS), a dispersant, and a plasticizer; and b. said colloidal dispersion further comprising a non-polymeric, ionizable surface modifier selected from the group consisting of organic acids wherein, said non-polymeric, ionizable surface modifier is an organic acid selected from the group consisting of aliphatic carboxylic acids, dicarboxylic acids, hydroxy carboxylic acids, and benzoic acids and wherein the composition has a pH of from about 3.6 to about 5.3. a. an aqueous colloidal dispersion comprising hydroxypropyl methyl cellulose acetate succinate (HPMCAS), a dispersant, and a plasticizer; and b. said colloidal dispersion further comprising a non-polymeric, ionizable surface modifier selected from the group consisting of organic acids wherein,
Method for manufacturing a thin layer of textured AIN comprising the following successive steps: a) providing a substrate having an amorphous surface, b) forming a polycrystalline nucleation layer of MS 2 with M = Mo, W or one of the alloys thereof, on the amorphous surface of the substrate, the polycrystalline nucleation layer consisting of crystalline domains, the base planes of which are parallel to the amorphous surface of the substrate, the crystalline domains being oriented randomly in an (a, b) plane formed by the amorphous surface of the substrate, c) depositing aluminum nitride on the nucleation layer, leading to the formation of a thin layer of textured AIN. a) providing a substrate having an amorphous surface, b) forming a polycrystalline nucleation layer of MS 2 with M = Mo, W or one of the alloys thereof, on the amorphous surface of the substrate, the polycrystalline nucleation layer consisting of crystalline domains, the base planes of which are parallel to the amorphous surface of the substrate, the crystalline domains being oriented randomly in an (a, b) plane formed by the amorphous surface of the substrate, c) depositing aluminum nitride on the nucleation layer, leading to the formation of a thin layer of textured AIN.