An implantable medical device comprising one or more polyhydroxyurethane 1 characterised in that the one or more polyhydroxyurethane is based on formula or on formula wherein R 1 is a linear or branched hydrocarbon chain, which may be unsubstituted or substituted and wherein one or more hydrocarbon group of said hydrocarbon chain may be replaced by an heteroatom, a ketone, a cycloalkyl, an heterocycle, an aryl or a heteroaryl, each of which may be substituted or unsubstituted, said hydrocarbon chain having from 2 to 60 carbon atoms; wherein R 2 is an aryl or a heteroaryl, each of which may be unsubstituted or substituted, or a linear or branched hydrocarbon chain, which may be unsubstituted or substituted, and wherein one or several hydrocarbon groups of said hydrocarbon chain may be replaced by a heteroatom, a cycloalkyl or an heterocycle, each of which may be unsubstituted or substituted, said hydrocarbon chain having at least 2 carbon atoms, preferably from 2 to 60 carbon atoms, more preferably from 2 to 20 carbon atoms, even more preferably from 2 to 15 carbon atoms, or a mixture thereof; preferably R 2 is an alkylene; wherein R 3 and R 4 are identical or different and represent H, a straight or branched saturated hydrocarbon chain C 1-6 -alkyl having 1 to 6 carbon atoms; C 1-6 -alkoxy alkyl having 1 to 6 carbon atoms and wherein n is an integer ≥ 1, preferably n is between 1 and 100, more preferably between 1 and 20; with the exception that if R 3 and/or R 4 represents an hydrogen atom, than R 1 is not or and with the exception that if R 3 and/or R 4 represents an hydrogen atom, then R 2 is not wherein R 8 is an aryl or a heteroaryl, each of which may be unsubstituted or substituted, or a linear or branched hydrocarbon chain, which may be unsubstituted or substituted, and wherein one or several hydrocarbon groups of said hydrocarbon chain may be replaced by a heteroatom, a cycloalkyl or an heterocycle, each of which may be unsubstituted or substituted, said hydrocarbon chain having at least 2 carbon atoms, in particular from 2 to 60 carbon atoms, more particularly from 2 to 20 carbon atoms, even more particularly from 2 to 15 carbon atoms, or a mixture thereof; preferably R 8 is an alkylene; and wherein u is an integer ≥ 1, preferably between 1 and 10 more preferably between 1 and 5. wherein R 1 is a linear or branched hydrocarbon chain, which may be unsubstituted or substituted and wherein one or more hydrocarbon group of said hydrocarbon chain may be replaced by an heteroatom, a ketone, a cycloalkyl, an heterocycle, an aryl or a heteroaryl, each of which may be substituted or unsubstituted, said hydrocarbon chain having from 2 to 60 carbon atoms; wherein R 2 is an aryl or a heteroaryl, each of which may be unsubstituted or substituted, or a linear or branched hydrocarbon chain, which may be unsubstituted or substituted, and wherein one or several hydrocarbon groups of said hydrocarbon chain may be replaced by a heteroatom, a cycloalkyl or an heterocycle, each of which may be unsubstituted or substituted, said hydrocarbon chain having at least 2 carbon atoms, preferably from 2 to 60 carbon atoms, more preferably from 2 to 20 carbon atoms, even more preferably from 2 to 15 carbon atoms, or a mixture thereof; preferably R 2 is an alkylene; wherein R 3 and R 4 are identical or different and represent H, a straight or branched saturated hydrocarbon chain C 1-6 -alkyl having 1 to 6 carbon atoms; C 1-6 -alkoxy alkyl having 1 to 6 carbon atoms and wherein n is an integer ≥ 1, preferably n is between 1 and 100, more preferably between 1 and 20; with the exception that if R 3 and/or R 4 represents an hydrogen atom, than R 1 is not or and with the exception that if R 3 and/or R 4 represents an hydrogen atom, then R 2 is not wherein R 8 is an aryl or a heteroaryl, each of which may be unsubstituted or substituted, or a linear or branched hydrocarbon chain, which may be unsubstituted or substituted, and wherein one or several hydrocarbon groups of said hydrocarbon chain may be replaced by a heteroatom, a cycloalkyl or an heterocycle, each of which may be unsubstituted or substituted, said hydrocarbon chain having at least 2 carbon atoms, in particular from 2 to 60 carbon atoms, more particularly from 2 to 20 carbon atoms, even more particularly from 2 to 15 carbon atoms, or a mixture thereof; preferably R 8 is an alkylene; and wherein u is an integer ≥ 1, preferably between 1 and 10 more preferably between 1 and 5.