Box for packaging pharmaceutical preparations, comprising - a box body (2, 3, 4, 5, 10'), which is accessible via an access opening, - a lid, which is adapted to close the access opening of the box body when in a closed state, the lid being connected to the box body at a hinge line and being swivelable about the hinge line for transfer from the closed state to an opened state, a tuck-in lid flap being connected to the lid, via a fold line, at an edge zone of the lid opposite to the hinge line, - a tamper-evident flap, which is connected to the box body, via a break line, at an edge zone of the access opening opposite to the hinge line of the lid, wherein the tamper-evident flap comprises a slot adapted to accommodate the lid flap when the lid is in its closed state, in which the lid covers the tamper-evident flap, - wherein the lid flap is adapted to interlock with the tamper-evident flap when the lid is in its closed state, the break line of the tamper-evident flap being damaged upon opening the lid for the first time, - wherein the lid flap comprises, beyond the fold line of the lid flap, an end area in which the lid flap is separated from the lid and which interlocks, when the lid is in its closed state, with an area of the tamper-evident flap adjacent to an end of the slot, - wherein the lid flap comprises end areas interlocking with respective areas of the tamper-evident flap at both ends, - wherein side flaps extend into the access opening, which are connected to the box body at fold lines running transversely to the hinge line of the lid, and - wherein the side flaps are adapted to underlie the tamper -evident flap but not to obstruct the slot, - characterised in that, after removal of the tamper-evident flap, the end areas of the lid flap slightly interlock with the side flaps, when the lid is in its closed state. - a box body (2, 3, 4, 5, 10'), which is accessible via an access opening, - a lid, which is adapted to close the access opening of the box body when in a closed state, the lid being connected to the box body at a hinge line and being swivelable about the hinge line for transfer from the closed state to an opened state, a tuck-in lid flap being connected to the lid, via a fold line, at an edge zone of the lid opposite to the hinge line, - a tamper-evident flap, which is connected to the box body, via a break line, at an edge zone of the access opening opposite to the hinge line of the lid, wherein the tamper-evident flap comprises a slot adapted to accommodate the lid flap when the lid is in its closed state, in which the lid covers the tamper-evident flap, - wherein the lid flap is adapted to interlock with the tamper-evident flap when the lid is in its closed state, the break line of the tamper-evident flap being damaged upon opening the lid for the first time, - wherein the lid flap comprises, beyond the fold line of the lid flap, an end area in which the lid flap is separated from the lid and which interlocks, when the lid is in its closed state, with an area of the tamper-evident flap adjacent to an end of the slot, - wherein the lid flap comprises end areas interlocking with respective areas of the tamper-evident flap at both ends, - wherein side flaps extend into the access opening, which are connected to the box body at fold lines running transversely to the hinge line of the lid, and - wherein the side flaps are adapted to underlie the tamper -evident flap but not to obstruct the slot, - characterised in that, after removal of the tamper-evident flap, the end areas of the lid flap slightly interlock with the side flaps, when the lid is in its closed state.