mhurhangee/ep-ind-claims huggingface dataset:
A method of determining loss-of-imprinting in the Insulin Growth Factor-2 gene of an individual, the method comprising, detecting the SNP genotype of the IGF2 gene in the individual, wherein (a) the genotype of at least SEQ ID NOs: 8, 11, 14, and 16, and optionally also SNPs selected from the group consisting of SEQ ID NOs: 1, 5, 9, 10, 2, 3, 4, 6, 7, 12, 13 and 15 is determined, or (b) the genotype of at least SEQ ID NOs: 1, 2, 4, 5, 8, 9, 10, 12, 13, 14, 15 and 16 is determined, thereby determining whether the individual is heterozygous or homozygous at each of the SNPs; quantifying in a sample from the individual the amount of RNA comprising two polymorphic options of at least one heterozygous SNP; determining a ratio of the amount of RNA comprising two polymorphic options of at least one heterozygous SNP; and correlating the RNA ratio to loss of imprinting of the IGF2 gene. (a) the genotype of at least SEQ ID NOs: 8, 11, 14, and 16, and optionally also SNPs selected from the group consisting of SEQ ID NOs: 1, 5, 9, 10, 2, 3, 4, 6, 7, 12, 13 and 15 is determined, or (b) the genotype of at least SEQ ID NOs: 1, 2, 4, 5, 8, 9, 10, 12, 13, 14, 15 and 16 is determined,
An apparatus, comprising: a housing; a fluid channel formed on the housing, wherein the fluid channel is coupled to an inlet and to an outlet; and a substrate positioned inside the fluid channel, wherein the substrate comprises: a plasmonic nanostructure and a sacrificial, conformal passivation coating deposited at least over the plasmonic nanostructure; the apparatus characterized by comprising: a reservoir, fluidly coupled to the fluid channel; wherein the reservoi contains a supply of liquid reagent for removing the passivation coating from the plasmonic nanostructure. a housing; a fluid channel formed on the housing, wherein the fluid channel is coupled to an inlet and to an outlet; and a substrate positioned inside the fluid channel, wherein the substrate comprises: a plasmonic nanostructure and a sacrificial, conformal passivation coating deposited at least over the plasmonic nanostructure; the apparatus characterized by comprising: a reservoir, fluidly coupled to the fluid channel; wherein the reservoi contains a supply of liquid reagent for removing the passivation coating from the plasmonic nanostructure. a plasmonic nanostructure and a sacrificial, conformal passivation coating deposited at least over the plasmonic nanostructure; the apparatus characterized by comprising: a reservoir, fluidly coupled to the fluid channel; wherein the reservoi contains a supply of liquid reagent for removing the passivation coating from the plasmonic nanostructure.
A pharmaceutical composition comprising as an active ingredient an oxymetazoline or a pharmaceutically acceptable salt or derivative thereof for use in the treatment of an ano-rectal disorder, wherein the concentration of the active ingredient is within the range of 0.05% to 1%.
Active vibration absorber for damping vibrations of a cantilevered portion of a support comprising at least two vibration modes, wherein the vibration absorber comprises a mass which is moved without using a spring via a drive which is controlled by a control device of the vibration absorber, a fastening device for fastening the drive to a support to be damped is coupled, so that, by way of a movement of the mass relative to the fastening device, an inertial force caused by the movement is transferred directly to the fastening device via the drive, the control device includes a motion sensor, characterised in that the control device includes at least two control loops formed to control vibrations of different frequency ranges, at least one of the control loops includes a bandpass and controls in a frequency range which includes one of the vibration modes, and the control device is configured to control the drive as a function of the signals of the motion sensor.
Device for fixing a WC basin to the wall, comprising a wedge-shaped adaptor which is configured as a closed hollow body with two large-area contact faces (1.1) and the wedge faces (1.2) connecting the large-area contact faces (1.1) together such that the two large-area contact faces (1.1) lie opposite each other at an angle prescribed by the wedge faces (1.2), one of these large-area contact faces serving as contact- and mounting face of the adaptor on the wall, and the other large-area contact face serving as contact- and mounting face for the WC basin, and the two large-area contact faces (1.1) having recesses (3, 4) orientated towards each other for conducting the fresh- and discharge water pipe.
A pharmaceutical composition comprising a saturated cladribine-cyclodextrin complex formulated into a solid oral dosage form, said composition being substantially free of cyclodextrin in excess of the minimum amount required to maximize the amount of cladribine in the complex or to maintain substantially all of the cladribine in the complex, wherein the cyclodextrin is γ-cyclodextrin or hydroxypropyl-β-cyclodextrin and wherein the weight ratio of cladribine to cyclodextrin is from 1:35 to 1:50.
A method of operation performed by a network node in a wireless communication network, the method comprising: calculating an actual resource element, RE, efficiency, wherein the actual RE efficiency is an actual number of information bits per resource element, RE, said calculating being based at least in part on an actual transport block size, TBS, obtained from a specification based on a link adaptation, LA, result and an actual buffer data volume; and determining an actual block error rate, BLER, from a searchable repository, based on the actual RE efficiency and an estimated SINR, wherein the estimated SINR is calculated using the following formula: SINR estimated = f CQI + OL _ adj, wherein the f is a mapping from a channel quality indicator, CQI, report to a specific SINR value and the OL_adj is an outer-loop adjustment, which is used to compensate a difference between reported CQI and actual channel quality. calculating an actual resource element, RE, efficiency, wherein the actual RE efficiency is an actual number of information bits per resource element, RE, said calculating being based at least in part on an actual transport block size, TBS, obtained from a specification based on a link adaptation, LA, result and an actual buffer data volume; and determining an actual block error rate, BLER, from a searchable repository, based on the actual RE efficiency and an estimated SINR, wherein the estimated SINR is calculated using the following formula: SINR estimated = f CQI + OL _ adj, wherein the f is a mapping from a channel quality indicator, CQI, report to a specific SINR value and the OL_adj is an outer-loop adjustment, which is used to compensate a difference between reported CQI and actual channel quality.
A powder-bed fusion additive manufacturing system (100, 300), comprising a beam combining system comprising: a first laser (406, 423) configured to emit a first light beam (407, 424) at a first wavelength; a second laser (408, 425) configured to emit a second light beam (409, 426) at a second wavelength different from the first wavelength; beam shaping optics (114, 314) that form a two-wavelength common beam (307, 411, 428), the beam shaping optics including at least one wavelength filter (410, 427) configured to pass the first light beam of the first wavelength and reflect the second light beam of the second wavelength in the common beam (411, 428); and a light patterning unit configured to receive the common beam and form a two-dimensional patterned beam, wherein the light patterning unit further comprises a pixel addressable light valve configured to apply a pattern on the common beam of light to provide the two-dimensional patterned beam of light, wherein the beam combining system further comprises an image relay configured to receive the two-dimensional patterned beam from the pixel addressable light valve and focus it as a two-dimensional image toward a predefined location of a powder bed, and wherein the valve is optically addressable to form a two-dimensional pattern. a first laser (406, 423) configured to emit a first light beam (407, 424) at a first wavelength; a second laser (408, 425) configured to emit a second light beam (409, 426) at a second wavelength different from the first wavelength; beam shaping optics (114, 314) that form a two-wavelength common beam (307, 411, 428), the beam shaping optics including at least one wavelength filter (410, 427) configured to pass the first light beam of the first wavelength and reflect the second light beam of the second wavelength in the common beam (411, 428); and a light patterning unit configured to receive the common beam and form a two-dimensional patterned beam, wherein the light patterning unit further comprises a pixel addressable light valve configured to apply a pattern on the common beam of light to provide the two-dimensional patterned beam of light, wherein the beam combining system further comprises an image relay configured to receive the two-dimensional patterned beam from the pixel addressable light valve and focus it as a two-dimensional image toward a predefined location of a powder bed, and wherein the valve is optically addressable to form a two-dimensional pattern.
A method for analyzing unauthorized intrusion into a computer network, the method comprising: allowing access to a virtualized operating system running on a hypervisor operating system hosted on a network device; using an introspection module comprising a virtual-machine-based rootkit module and its associated userland processes running on the hypervisor operating system to intercept a network attack on the virtualized operating system, wherein the network attack includes attack-identifying information; generating forensic data on the network attack from the attack-identifying information; generating an attack signature from the forensic data; and providing the attack signature to an intrusion prevention system configured to control access to a protected network using the attack signature to identify subsequent attacks. allowing access to a virtualized operating system running on a hypervisor operating system hosted on a network device; using an introspection module comprising a virtual-machine-based rootkit module and its associated userland processes running on the hypervisor operating system to intercept a network attack on the virtualized operating system, wherein the network attack includes attack-identifying information; generating forensic data on the network attack from the attack-identifying information; generating an attack signature from the forensic data; and providing the attack signature to an intrusion prevention system configured to control access to a protected network using the attack signature to identify subsequent attacks.
A composition for use in treating Fragile X syndrome in a subject in need thereof, wherein said composition comprises a modulator of a chloride transporter, wherein said modulator is an inhibitor of a transporter involved in the importation of chloride into neurons, wherein said transporter is NKCC1, wherein the inhibitor of NKCC1 is selected from the group consisting of bumetanide, an analog of bumetanide, furosemide, ethacrynic acid, torsemide, azosemide, muzolimine, piretanide and tripamide, and wherein the analog of bumetanide is selected from the group consisting of bumetanide aldehyde, bumetanide dibenzylamide, bumetanide diethylamide, bumetanide morpholinoethyl ester, bumetanide 3-(dimethylaminopropyl) ester, bumetanide N,N-diethylglycolamide ester, bumetanide dimethylglycolamide ester, bumetanide pivaxetil ester, bumetanide methoxy(polyethyleneoxy) n-1 -ethyl ester, bumetanide benzyltrimethyl-ammonium salt, bumetanide cetyltrimethylammonium salt, pivaloyloxymethyl ester of bumetanide, methyl ester of bumetanide, N,N-dimethylaminoethyl ester of bumetanide, bumetanide [-(C=O)-SH] thioacid, bumetanide S-methyl thioester, bumetanide S-cyanotnethyl thioester, bumetanide S-ethyl thioester, bumetanide S-isoamyl thioester, bumetanide S-octyl thioester, bumetanide S-benzyl thioester, bumetanide S-(morpholinoethyl) thioester, bumetanide S-[3- (dimethylaminopropyl)] thioester, bumetanide S-(N,N-diethylglycolamido)thioester, bumetanide S-(N,N-dimethylglycolamido)thioester, bumetanide S-pivaxetil thioester, bumetanide S-propaxetil thioester, bumetanide S-(methoxypolyethyleneoxy) n-1 -ethyl] thioester, bumetanide [-(C=O)-S -] benzyltrimethyl-ammonium thioacid salt and bumetanide [-(C=O)-S] cetyltrimethylammonium thioacid salt, metastable bumetanide thioacid, bumetanide thioaldehyde, bumetanide O-methyl thioester, bumetanide O-cyanomethyl thioester, bumetanide O-ethyl thioester, bumetanide O-isoamyl thioester, bumetanide O-octyl thioester, bumetanide O-benzyl thioester, bumetanide O-(morpholinoethyl) thioester, bumetanide O-[3-(dimethylaminopropyl)] thioester, bumetanide O-(N,N-diethylglycolamido)thioester, bumetanide O-pivaxetil thioester, bumetanide O-propaxetil thioester, bumetanide O-[methoxy(polyethyleneoxy) n-1 ethyl] thioester, bumetanide [-(C=S)-O -] benzyltrimethyl-ammonium thioacid salt and bumetanide [-(C=S)-O -] cetyltrimethylammonium thioacid salt.
Household cooking appliance (B1; B2; B3), having - a plurality of electrically operable heating elements for heating a cooking compartment, - a mechanically switching operation selection switch for connecting at least one heating element as a function of the switch position thereof, - a mechanical temperature regulator for regulating the connected heating element as a function of a temperature of the cooking compartment, which mechanical temperature regulator is connected electrically in series with the heating elements, and - an electronic circuit (11; 23), wherein - a heating circuit relay is connected electrically in series with the heating elements and the mechanical temperature regulator and is able to be switched by means of the electronic circuit (11; 23) and - the electronic circuit (11; 23) is connected to the operation selection switch in order to identify a switch position set by the operation selection switch, characterised in that - the electronic circuit (11; 23) is configured to switch the heating circuit relay on and off during continuous operation as a function of the identified switch position with a predefined switching pattern. - a plurality of electrically operable heating elements for heating a cooking compartment, - a mechanically switching operation selection switch for connecting at least one heating element as a function of the switch position thereof, - a mechanical temperature regulator for regulating the connected heating element as a function of a temperature of the cooking compartment, which mechanical temperature regulator is connected electrically in series with the heating elements, and - an electronic circuit (11; 23), wherein - a heating circuit relay is connected electrically in series with the heating elements and the mechanical temperature regulator and is able to be switched by means of the electronic circuit (11; 23) and - the electronic circuit (11; 23) is connected to the operation selection switch in order to identify a switch position set by the operation selection switch, characterised in that - the electronic circuit (11; 23) is configured to switch the heating circuit relay on and off during continuous operation as a function of the identified switch position with a predefined switching pattern.
A method for formulating an ink for a gravure printing press, said method comprising: digital inkjet printing of a décor and a patch onto a substrate, said patch comprising between three and eight color reference areas, said color reference areas comprising the digital ink-jet inks used for composing the printed décor, and wherein said patch is located on a part of said substrate, said part being substantially free of said décor; measuring the colors of said color reference areas of the patch; adjusting a tone of an ink for gravure printing on the basis of said measure. digital inkjet printing of a décor and a patch onto a substrate, said patch comprising between three and eight color reference areas, said color reference areas comprising the digital ink-jet inks used for composing the printed décor, and wherein said patch is located on a part of said substrate, said part being substantially free of said décor; measuring the colors of said color reference areas of the patch; adjusting a tone of an ink for gravure printing on the basis of said measure.
A memory device (100, 200, 300) comprising: a memory array (104, 204, 304, 402, 502, 614) including a plurality of bit cells (408, 504, 506), wherein each bit cell of the plurality of bit cells (408, 504, 506) is configured to switch between a first state and a second state; a short detection component (116, 316, 400, 500, 600) configured to identify at least one bit cell (408, 504) of the plurality of bit cells (408, 410, 504, 506) fixed in one of the first or second states, wherein the short detection component (116, 316, 400, 500, 600) is configured to identify the at least one bit cell (408, 504) based at least in part on a comparison of a reference voltage representing a reference resistance with a corresponding voltage representing a resistance associated with the at least one bit cell (408, 504) being sampled; and an inversion component (118, 218, 318) configured to determine that a state of a first data bit to be stored in the at least one bit cell (408, 504) differs from the fixed state of the at least one bit cell (408, 504); and invert the first data bit, in response to determining that the state of the first data bit differs from the fixed state of the at least one bit cell (408, 504). a memory array (104, 204, 304, 402, 502, 614) including a plurality of bit cells (408, 504, 506), wherein each bit cell of the plurality of bit cells (408, 504, 506) is configured to switch between a first state and a second state; a short detection component (116, 316, 400, 500, 600) configured to identify at least one bit cell (408, 504) of the plurality of bit cells (408, 410, 504, 506) fixed in one of the first or second states, wherein the short detection component (116, 316, 400, 500, 600) is configured to identify the at least one bit cell (408, 504) based at least in part on a comparison of a reference voltage representing a reference resistance with a corresponding voltage representing a resistance associated with the at least one bit cell (408, 504) being sampled; and an inversion component (118, 218, 318) configured to determine that a state of a first data bit to be stored in the at least one bit cell (408, 504) differs from the fixed state of the at least one bit cell (408, 504); and invert the first data bit, in response to determining that the state of the first data bit differs from the fixed state of the at least one bit cell (408, 504).
A controlled motion system comprising: a track comprising a linear magnetic motor having a stator, wherein the stator comprises: a base having a plurality of teeth (109, 111, 113), wherein at least some of the plurality of teeth include electromagnetic coils configured to produce a magnetic flux, and a bridge element to reduce variation in the air gap reluctance, the bridge element being a sheet disposed on top of the plurality of teeth of the stator, and the bridge element being made of a material having a magnetic permeability of 5.0 x 10-3 H/m or greater; and one or more movers mounted to move along the track by utilizing the magnetic flux. a track comprising a linear magnetic motor having a stator, wherein the stator comprises: a base having a plurality of teeth (109, 111, 113), wherein at least some of the plurality of teeth include electromagnetic coils configured to produce a magnetic flux, and a bridge element to reduce variation in the air gap reluctance, the bridge element being a sheet disposed on top of the plurality of teeth of the stator, and the bridge element being made of a material having a magnetic permeability of 5.0 x 10-3 H/m or greater; and a base having a plurality of teeth (109, 111, 113), wherein at least some of the plurality of teeth include electromagnetic coils configured to produce a magnetic flux, and a bridge element to reduce variation in the air gap reluctance, the bridge element being a sheet disposed on top of the plurality of teeth of the stator, and the bridge element being made of a material having a magnetic permeability of 5.0 x 10-3 H/m or greater; and one or more movers mounted to move along the track by utilizing the magnetic flux.
A method for preparing an anti-counterfeit film having an amphichroic pattern, comprising the following steps: mixing a polymerizable liquid crystal material of chiral structure and a photoinitiator, heating the mixture to a temperature in the range of 80 to 120°C, blade-coating the mixture on a base film, then drying the coated base film; subjecting the product of step to a local exposure by locating a ultraviolet lamp, followed by drying at a different temperature from that of drying in step, and another exposure of ultraviolet, to obtain an anti-counterfeit film having an amphichroic pattern; said polymerizable liquid crystal material of chiral structure is a cholesteric siloxane liquid crystal. mixing a polymerizable liquid crystal material of chiral structure and a photoinitiator, heating the mixture to a temperature in the range of 80 to 120°C, blade-coating the mixture on a base film, then drying the coated base film; subjecting the product of step to a local exposure by locating a ultraviolet lamp, followed by drying at a different temperature from that of drying in step, and another exposure of ultraviolet, to obtain an anti-counterfeit film having an amphichroic pattern; said polymerizable liquid crystal material of chiral structure is a cholesteric siloxane liquid crystal.
A first connector for exchanging power and data with a receiving system of a device (1000, 1306) with a second magnet 1314a-b), the first connector magnetically couplable with a second connector (1006, 1302) of the device, the first connector comprising: a connector body (1014, 1018, 1021, 1100, 1200) coupled to a cable (1010, 1023, 1022, 1212); a first permanent ring magnet (1116a-b, 1218a-b) disposed within the connector body and configured such that the connector body is alignable and magnetically couplable with the second connector and configurable to interact with the second magnet; and a transmission system (614, 616, 618, 620, 714, 716, 718, 814, 816, 818, 820) disposed within the connector body, wherein the transmission system is configurable to send at least one of power and data via inductive charging and/or radio frequency data communication to the receiving system of the device in any one of the multiple orientations in which the first permanent ring magnet is magnetically coupled to the second magnet, the transmission system being positioned relative the first permanent ring magnet so that the transmission system is alignable with the receiving system. a connector body (1014, 1018, 1021, 1100, 1200) coupled to a cable (1010, 1023, 1022, 1212); a first permanent ring magnet (1116a-b, 1218a-b) disposed within the connector body and configured such that the connector body is alignable and magnetically couplable with the second connector and configurable to interact with the second magnet; and a transmission system (614, 616, 618, 620, 714, 716, 718, 814, 816, 818, 820) disposed within the connector body, wherein the transmission system is configurable to send at least one of power and data via inductive charging and/or radio frequency data communication to the receiving system of the device in any one of the multiple orientations in which the first permanent ring magnet is magnetically coupled to the second magnet, the transmission system being positioned relative the first permanent ring magnet so that the transmission system is alignable with the receiving system.