A compound having the formula an addition salts thereof; or a stereochemically isomeric form thereof or a tautomeric form thereof; wherein each Alk independently is C 1-6 alkanediyl; Q is hydrogen; C 1-6 alkyl substituted with one or two Ar 2 radicals; C 1-6 alkyl substituted with quinolinyl, oxazolidinyl, thiazolidinyl, morpholinyl, thiomorpholinyl, or with pyrrolidinonyl; -CO-Ar 2; or Q is a radical of formula wherein t is 1, 2 or 3; R 4 is amino, mono-or di(C 1-6 alkyl)amino; R 1 is quinolinyl R 2 is Ar 2, -CO-Ar 2, morpholinyl or quinolinyl where Q is other than hydrogen, R 3 is hydrogen; or where Q is hydrogen, R 3 is a radical of formula: wherein R 6 is selected from hydrogen, C 1-6 alkyl, Ar 2 C 1-6 alkyl, hydroxyC 1-6 alkyl, (C 1-6 alkyloxy)C 1-6 alkyl, aminoC 1-6 alkyl, mono- and di(C 1-6 alkyl)amino-C 1-6 alkyl, carboxylC 1-6 alkyl, C 1-6 alkyloxycarbonylC 1-6 alkyl, aminocarbonyl-C 1-6 alkyl, mono- and dl(C 1-6 alkyl)aminocarbonylC 1-6 alkyl; R 7, R 8, R 9 each independently are selected from halo, cyano, C 1-6 alkyl, Ar 1 -C 1-6 alkyl, cyanoC 1-6 alkyl, C 2-6 alkenyl, cyanoC 2-6 alkenyl, C 2-6 alkynyl, cyanoC 2-6 alkynyl, Ar 1, R 10a -O-, R 10a -S-, -N(R 5a R 5b), polyhaloC 1-6 alkyl, R 10a -O-C(=O)-, N(R 5a R 5b)-C(=O)-, R 10a -O-C 1-6 alkyl, N(R 5a R 5b)-C 1-6 alkyl, R 10a -O-C(=O)-C 1-6 alkyl, N(R 5a R 5b)-C(=O)-C 1-6 alkyl, R 10a -C(=O)-NR 5b -, R 10b -C(=O)-O-, R 10b -C(=O)-O-C 1-6 alkyl; and R 8 and/or R 9 may also be hydrogen; each R 5a and R 5b independently from each other are hydrogen or C 1-6 alkyl; R 10a is hydrogen, C 1-6 alkyl or Ar 1 C 1-6 alkyl; R 10b is C 1-6 alkyl or Ar 1 C 1-6 alkyl; Ar 1 is phenyl or phenyl substituted with 1, 2, 3 or 4 substituents independently selected from halo, hydroxy, C 1-6 alkyl, hydroxyC 1-6 alkyl, polyhaloC 1-6 alkyl and C 1-6 alkyloxy; Ar 2 is phenyl or phenyl substituted with 1, 2, 3 or 4 substituents independently selected from halo, hydroxy, C 1-6 alkyl, cyano, nitro, hydroxyC 1-6 alkyl, polyhaloC 1-6 alkyl, C 1-6 alkyloxy, hydroxyC 1-6 alkyloxy, C 1-6 alkyloxycarbonyl, Ar 1 and Ar 1 O. each Alk independently is C 1-6 alkanediyl; Q is hydrogen; C 1-6 alkyl substituted with one or two Ar 2 radicals; C 1-6 alkyl substituted with quinolinyl, oxazolidinyl, thiazolidinyl, morpholinyl, thiomorpholinyl, or with pyrrolidinonyl; -CO-Ar 2; or Q is a radical of formula wherein t is 1, 2 or 3; R 4 is amino, mono-or di(C 1-6 alkyl)amino; R 1 is quinolinyl R 2 is Ar 2, -CO-Ar 2, morpholinyl or quinolinyl where Q is other than hydrogen, R 3 is hydrogen; or where Q is hydrogen, R 3 is a radical of formula: wherein R 6 is selected from hydrogen, C 1-6 alkyl, Ar 2 C 1-6 alkyl, hydroxyC 1-6 alkyl, (C 1-6 alkyloxy)C 1-6 alkyl, aminoC 1-6 alkyl, mono- and di(C 1-6 alkyl)amino-C 1-6 alkyl, carboxylC 1-6 alkyl, C 1-6 alkyloxycarbonylC 1-6 alkyl, aminocarbonyl-C 1-6 alkyl, mono- and dl(C 1-6 alkyl)aminocarbonylC 1-6 alkyl; R 7, R 8, R 9 each independently are selected from halo, cyano, C 1-6 alkyl, Ar 1 -C 1-6 alkyl, cyanoC 1-6 alkyl, C 2-6 alkenyl, cyanoC 2-6 alkenyl, C 2-6 alkynyl, cyanoC 2-6 alkynyl, Ar 1, R 10a -O-, R 10a -S-, -N(R 5a R 5b), polyhaloC 1-6 alkyl, R 10a -O-C(=O)-, N(R 5a R 5b)-C(=O)-, R 10a -O-C 1-6 alkyl, N(R 5a R 5b)-C 1-6 alkyl, R 10a -O-C(=O)-C 1-6 alkyl, N(R 5a R 5b)-C(=O)-C 1-6 alkyl, R 10a -C(=O)-NR 5b -, R 10b -C(=O)-O-, R 10b -C(=O)-O-C 1-6 alkyl; and R 8 and/or R 9 may also be hydrogen; each R 5a and R 5b independently from each other are hydrogen or C 1-6 alkyl; R 10a is hydrogen, C 1-6 alkyl or Ar 1 C 1-6 alkyl; R 10b is C 1-6 alkyl or Ar 1 C 1-6 alkyl; Ar 1 is phenyl or phenyl substituted with 1, 2, 3 or 4 substituents independently selected from halo, hydroxy, C 1-6 alkyl, hydroxyC 1-6 alkyl, polyhaloC 1-6 alkyl and C 1-6 alkyloxy; Ar 2 is phenyl or phenyl substituted with 1, 2, 3 or 4 substituents independently selected from halo, hydroxy, C 1-6 alkyl, cyano, nitro, hydroxyC 1-6 alkyl, polyhaloC 1-6 alkyl, C 1-6 alkyloxy, hydroxyC 1-6 alkyloxy, C 1-6 alkyloxycarbonyl, Ar 1 and Ar 1 O.