A process for the production of cannabidiol or another neutral cannabinoid, said process comprising: i) contacting a biomass containing CBD and/or CBDA, or said another neutral cannabinoid or in the form of carboxylic acid, with an extraction solvent for at least 10 minutes at a temperature between 0°C and the reflux temperature of the solvent, to obtain, after biomass removal, an extraction solution; said extraction solvent selected from the group consisting of pentane, hexane, heptane, octane, methylcyclohexane, acetone, propanol, ethanol, methanol, ethyl acetate, toluene, methylene chloride, and mixtures thereof; continuing according to a process comprising: ii-a) contacting the extraction solution with a hydro-alcoholic solution and adjusting pH to 7.5-12.5 with a suitable alkaline solution, to obtain, after phase separation, a first hydro-alcoholic phase and a first organic phase; if the extraction solvent is a water-miscible solvent, adding also a first water-immiscible solvent selected from the group consisting of pentane, hexane, heptane, methylcyclohexane, and mixtures thereof; iii-a) contacting the first hydro-alcoholic phase with a second water-immiscible solvent and an acid solution adapted to bring pH to 2.0-6.5 to obtain a second organic phase and a second hydro-alcoholic phase; said second water-immiscible solvent selected from the group consisting of pentane, hexane, heptane, methylcyclohexane, and mixtures thereof; iv-a) concentrating the second organic phase and subjecting the resulting oil to heating at a temperature between 65 °C and 180 °C for a time period of at least 10 minutes to obtain the decarboxylation of CBDA to CBD; or continuing according to a second process comprising: ii-b) concentrating the extraction solution up to obtain an extraction oil and contacting the extraction oil with an alcohol at a temperature less than 20°C for at least 10 minutes to obtain a suspension of extract and waxes, said alcohol selected from the group consisting of methanol, ethanol, propanol, and mixtures thereof; iii-b) filtering and concentrating the suspension to obtain a wax-free extraction oil and contacting the wax-free extraction oil with an organic water-immiscible solvent and a hydro-alcoholic solution to obtain an organic phase containing the wax- and pitch-free extract and a hydro-alcoholic, pitch-containing phase; iv-b) concentrating the organic phase containing the wax- and pitch-free extract and subjecting to silica gel chromatography using a suitable eluent phase and collecting the fractions containing CBD, or said another neutral cannabinoid; and ending with v) crystallizing CBD, or said another neutral cannabinoid, from a third water-immiscible solvent selected from the group consisting of pentane, hexane, heptane, octane, methylcyclohexane, and mixtures thereof. i) contacting a biomass containing CBD and/or CBDA, or said another neutral cannabinoid or in the form of carboxylic acid, with an extraction solvent for at least 10 minutes at a temperature between 0°C and the reflux temperature of the solvent, to obtain, after biomass removal, an extraction solution; said extraction solvent selected from the group consisting of pentane, hexane, heptane, octane, methylcyclohexane, acetone, propanol, ethanol, methanol, ethyl acetate, toluene, methylene chloride, and mixtures thereof; ii-a) contacting the extraction solution with a hydro-alcoholic solution and adjusting pH to 7.5-12.5 with a suitable alkaline solution, to obtain, after phase separation, a first hydro-alcoholic phase and a first organic phase; if the extraction solvent is a water-miscible solvent, adding also a first water-immiscible solvent selected from the group consisting of pentane, hexane, heptane, methylcyclohexane, and mixtures thereof; iii-a) contacting the first hydro-alcoholic phase with a second water-immiscible solvent and an acid solution adapted to bring pH to 2.0-6.5 to obtain a second organic phase and a second hydro-alcoholic phase; said second water-immiscible solvent selected from the group consisting of pentane, hexane, heptane, methylcyclohexane, and mixtures thereof; iv-a) concentrating the second organic phase and subjecting the resulting oil to heating at a temperature between 65 °C and 180 °C for a time period of at least 10 minutes to obtain the decarboxylation of CBDA to CBD; ii-b) concentrating the extraction solution up to obtain an extraction oil and contacting the extraction oil with an alcohol at a temperature less than 20°C for at least 10 minutes to obtain a suspension of extract and waxes, said alcohol selected from the group consisting of methanol, ethanol, propanol, and mixtures thereof; iii-b) filtering and concentrating the suspension to obtain a wax-free extraction oil and contacting the wax-free extraction oil with an organic water-immiscible solvent and a hydro-alcoholic solution to obtain an organic phase containing the wax- and pitch-free extract and a hydro-alcoholic, pitch-containing phase; iv-b) concentrating the organic phase containing the wax- and pitch-free extract and subjecting to silica gel chromatography using a suitable eluent phase and collecting the fractions containing CBD, or said another neutral cannabinoid; and ending with v) crystallizing CBD, or said another neutral cannabinoid, from a third water-immiscible solvent selected from the group consisting of pentane, hexane, heptane, octane, methylcyclohexane, and mixtures thereof.