A filter capsule-tube assembly (80', 80", 80′′′) comprising: a shell (90', 90", 90′′′) having a housing wall defining a filter chamber with at least one port stem defining a port channel formed on the shell (90', 90", 90′′′) wherein the port channel is in fluid communication with the filter chamber; a rigid tube connector (82', 82", 82′′′) secured to the at least one port stem; and, a flexible tube (14', 14", 14′′′) defining a lumen; characterized by the tube connector (82', 82", 82′′′) having a connector wall that defines a tube bore dimensioned to receive and register against an outer surface of the flexible tube (14', 14", 14′′′), wherein a bottom end of tube bore is formed as an annular channel with a bottom surface, and wherein the tube connector (82', 82", 82′′′) has portions defining a capsule port receiving bore, wherein an inner channel wall that partially defines a tube receiving channel defines a connector bore, said tube receiving channel having an inner channel wall with a frustoconical shape in cross-section that is adapted to create a restriction surface to mechanically lock tube to the connector when bonded to the connector, wherein the tube connector (82', 82", 82′′′) is secured to the at least one port stem via the capsule port receiving bore, wherein the flexible tube (14', 14", 14′′′) is bonded to the tube connector (82', 82", 82′′′) with an end of the tube (14', 14", 14′′′) secured in the tube receiving channel, wherein an end of the flexible tube registers against the bottom surface that functions as a tube stop, and wherein the connector bore, tube lumen and port channel are in fluid communication, said filter capsule-tube assembly being characterized in that an inner annular surface of the inner wall of the annular channel defines a connector channel in fluid communication with a port channel defined by port wall and port base as well of the chamber defined by capsule, wherein the cross-sectional diameter of the narrowest portion of connector channel is the same as, or not less than the cross-sectional diameter of the lumen of tube taken at a relaxed, unstressed portion of the tube. a shell (90', 90", 90′′′) having a housing wall defining a filter chamber with at least one port stem defining a port channel formed on the shell (90', 90", 90′′′) wherein the port channel is in fluid communication with the filter chamber; a rigid tube connector (82', 82", 82′′′) secured to the at least one port stem; and, a flexible tube (14', 14", 14′′′) defining a lumen; characterized by the tube connector (82', 82", 82′′′) having a connector wall that defines a tube bore dimensioned to receive and register against an outer surface of the flexible tube (14', 14", 14′′′), wherein a bottom end of tube bore is formed as an annular channel with a bottom surface, and wherein the tube connector (82', 82", 82′′′) has portions defining a capsule port receiving bore, wherein an inner channel wall that partially defines a tube receiving channel defines a connector bore, said tube receiving channel having an inner channel wall with a frustoconical shape in cross-section that is adapted to create a restriction surface to mechanically lock tube to the connector when bonded to the connector, wherein the tube connector (82', 82", 82′′′) is secured to the at least one port stem via the capsule port receiving bore, wherein the flexible tube (14', 14", 14′′′) is bonded to the tube connector (82', 82", 82′′′) with an end of the tube (14', 14", 14′′′) secured in the tube receiving channel, wherein an end of the flexible tube registers against the bottom surface that functions as a tube stop, and wherein the connector bore, tube lumen and port channel are in fluid communication, said filter capsule-tube assembly being characterized in that an inner annular surface of the inner wall of the annular channel defines a connector channel in fluid communication with a port channel defined by port wall and port base as well of the chamber defined by capsule, wherein the cross-sectional diameter of the narrowest portion of connector channel is the same as, or not less than the cross-sectional diameter of the lumen of tube taken at a relaxed, unstressed portion of the tube.