A microscope that generates a combined image (34; 54; 64) from multiple individual images (28a to 28d; 52a to 52d; 62a to 62d) of an object (30; 50; 60), comprising at least one illumination device (22; 22a, 22b) that illuminates the object (30; 50; 60) from at least two different illumination directions (24a, 24b), an image acquisition unit that acquires multiple individual images (28a to 28d; 52a to 52d; 62a to 62d) of the object (30; 50; 60) illuminated from the at least two different illumination directions (24a, 24b), and an image combination unit that combines the individual images (28a to 28d; 52a to 52d; 62a to 62d) and thereby generates the combined image (34; 54; 64), wherein the image combination unit is configured to compensate, upon combination of the individual images (28a to 28d; 52a to 52d; 62a to 62d), for an image information loss connected with an image artifact of one of the individual images (28a to 28d; 52a to 52d; 62a to 62d), utilizing an image information of at least one other of the individual images (28a to 28d; 52a to 52d; 62a to 62d) in the combined image (34; 54; 64), characterized by a control system that controls the image acquisition unit and is configured to acquire the individual images (28a to 28d; 52a to 52d; 62a to 62d) at a constant image refresh rate (f r) and thus to generate a live stream of multiple combined images, wherein the illumination device is configured to adjust the azimuth angle (β) and the elevation angle (α) of the at least two different illumination directions (24a, 24b), wherein the image acquisition unit is configured to acquire the individual images (28a to 28d) as a sequence of four chronologically successive individual images (28a to 28d), the four chronologically successive individual images (28a to 28d) including a first to a fourth highlight region (36a to 36d), and the first to the fourth highlight regions (36a to 36d) being associated with a first to a fourth illumination direction (24a to 24d), and the first to the fourth illumination directions (24a to 24d) respectively having an azimuth angle (β) of 0°, 90°, 180° and 270° and an identical elevation angle (α), and the illumination device being configured to generate the first to the fourth illumination direction (24a to 24d) utilizing a displaceable aperture stop in the illumination beam path of the microscope. at least one illumination device (22; 22a, 22b) that illuminates the object (30; 50; 60) from at least two different illumination directions (24a, 24b), an image acquisition unit that acquires multiple individual images (28a to 28d; 52a to 52d; 62a to 62d) of the object (30; 50; 60) illuminated from the at least two different illumination directions (24a, 24b), and an image combination unit that combines the individual images (28a to 28d; 52a to 52d; 62a to 62d) and thereby generates the combined image (34; 54; 64), wherein the image combination unit is configured to compensate, upon combination of the individual images (28a to 28d; 52a to 52d; 62a to 62d), for an image information loss connected with an image artifact of one of the individual images (28a to 28d; 52a to 52d; 62a to 62d), utilizing an image information of at least one other of the individual images (28a to 28d; 52a to 52d; 62a to 62d) in the combined image (34; 54; 64), characterized by a control system that controls the image acquisition unit and is configured to acquire the individual images (28a to 28d; 52a to 52d; 62a to 62d) at a constant image refresh rate (f r) and thus to generate a live stream of multiple combined images, wherein the illumination device is configured to adjust the azimuth angle (β) and the elevation angle (α) of the at least two different illumination directions (24a, 24b), wherein the image acquisition unit is configured to acquire the individual images (28a to 28d) as a sequence of four chronologically successive individual images (28a to 28d), the four chronologically successive individual images (28a to 28d) including a first to a fourth highlight region (36a to 36d), and the first to the fourth highlight regions (36a to 36d) being associated with a first to a fourth illumination direction (24a to 24d), and the first to the fourth illumination directions (24a to 24d) respectively having an azimuth angle (β) of 0°, 90°, 180° and 270° and an identical elevation angle (α), and the illumination device being configured to generate the first to the fourth illumination direction (24a to 24d) utilizing a displaceable aperture stop in the illumination beam path of the microscope.