mhurhangee/ep-ind-claims huggingface dataset:
A method for correcting color artifacts in an image having a plurality of pixels, the method comprising: receiving image data of the image, the image data including a luma component value and two chroma components values for each of the plurality of pixels in the image; and detecting at least one color artifact in the luma component values of the image data, characterized in that the method further comprises: generating a correction ratio map having an entry for each of the plurality of pixels in the image, the entry indicating a type of colour artifact associated with a corresponding pixel, the correction ratio map indicating the location of the at least one color artifact in the image data; applying a plurality of directional median filters to each chroma component to generate a plurality of median values for a subset of the chroma component values; for each of the subset of chroma component values, selecting one of the plurality of median values based at least partly on a corresponding correction ratio map entry; and outputting a corrected chroma value for the corresponding pixel based at least partly on the selected one of the plurality of median values. receiving image data of the image, the image data including a luma component value and two chroma components values for each of the plurality of pixels in the image; and detecting at least one color artifact in the luma component values of the image data, characterized in that the method further comprises: generating a correction ratio map having an entry for each of the plurality of pixels in the image, the entry indicating a type of colour artifact associated with a corresponding pixel, the correction ratio map indicating the location of the at least one color artifact in the image data; applying a plurality of directional median filters to each chroma component to generate a plurality of median values for a subset of the chroma component values; for each of the subset of chroma component values, selecting one of the plurality of median values based at least partly on a corresponding correction ratio map entry; and outputting a corrected chroma value for the corresponding pixel based at least generating a correction ratio map having an entry for each of the plurality of pixels in the image, the entry indicating a type of colour artifact associated with a corresponding pixel, the correction ratio map indicating the location of the at least one color artifact in the image data; applying a plurality of directional median filters to each chroma component to generate a plurality of median values for a subset of the chroma component values; for each of the subset of chroma component values, selecting one of the plurality of median values based at least partly on a corresponding correction ratio map entry; and outputting a corrected chroma value for the corresponding pixel based at least partly on the selected one of the plurality of median values.
A hydrogel for use in promoting skin regeneration comprising topically administering to a subject with an area of a full thickness skin injury damaging the skin, the hydrogel on at least a portion of the injured area, the hydrogel comprising a crosslinked composition comprising: at least 80% of a polysaccharide with at least one monomer having at least one substituted hydroxyl group, wherein the substituted hydroxyl group has the formula: -O 1 -C NR 7 -CH 2 CH=CH 2 wherein O 1 is the oxygen atom of said substituted hydroxyl group, R 7 is hydrogen or C 1 -C 4 alkyl, wherein the degree of substitution of formula on the polysaccharide is less than 0.2, and wherein the polysaccharide is dextran; and up to 20% of a second crosslinkable molecule, thereby promoting skin regeneration in the injured area. wherein O 1 is the oxygen atom of said substituted hydroxyl group, R 7 is hydrogen or C 1 -C 4 alkyl, wherein the degree of substitution of formula on the polysaccharide is less than 0.2, and wherein the polysaccharide is dextran; and up to 20% of a second crosslinkable molecule, thereby promoting skin regeneration in the injured area.
A process for isomerizing one or more C 4 -C 24 alpha olefins to produce an isomerization mixture comprising one or more C 4 -C 24 internal olefins, the process comprising contacting an olefinic feed comprising the one or more C 4 -C 24 alpha olefins with a catalyst under isomerization conditions, wherein the catalyst comprises a microporous crystalline aluminosilicate from the ZSM-48 group having a SiO 2 /Al 2 O 3 molar ratio of less than or equal to 100.
Device for determining the hydrostatic pressure in a solid/liquid mixture (20,21), the device comprising a housing, a part of which is permeable to the liquid (20, 21), and which further comprises a liquid chamber connecting to the permeable part and a pressure sensor connecting to the liquid chamber, characterised in that the liquid chamber comprises an inlet for a flushing liquid and the permeable part is also permeable to the flushing liquid.
Method for making a feedthrough comprising the following steps: a/ positioning of a body comprising a metallic wall with an orifice passing straight through it on a base of a tooling, preferably one made of graphite; b/ placing of the outer portion (92, 93) of the tooling around the body; c/ insertion of one or more metallic pins in the orifice emerging from the wall and then filling the rest of the orifice with a frit of electrically insulating material; d/ placing the upper portion of the tool forming a piston against a zone including the orifice filled with the frit of electrically insulating material, preferably a glass frit, and in which the one or more pins is (are) inserted; e/ application of a temperature and pressure cycle, and a displacement of the piston, to carry out a flash sintering process. a/ positioning of a body comprising a metallic wall with an orifice passing straight through it on a base of a tooling, preferably one made of graphite; b/ placing of the outer portion (92, 93) of the tooling around the body; c/ insertion of one or more metallic pins in the orifice emerging from the wall and then filling the rest of the orifice with a frit of electrically insulating material; d/ placing the upper portion of the tool forming a piston against a zone including the orifice filled with the frit of electrically insulating material, preferably a glass frit, and in which the one or more pins is (are) inserted; e/ application of a temperature and pressure cycle, and a displacement of the piston, to carry out a flash sintering process.
An anti-PD-L1 antibody for use in combination with crizotinib, or a pharmaceutically acceptable salt or solvate thereof, for treating or delaying progression of an ALK-negative cancer in an individual.
An implant extractor comprising: a first arm having a proximal end, a distal end for attachment to a first jaw, and a second arm having a proximal end and a distal end, wherein the first arm further comprises: an adjustment mechanism that includes: an adjuster, and a lever having a proximal end engaged with the adjuster and a distal end pivotably connected to the second arm; and wherein the implant extractor further comprises a link pivotably connected to the first and second arms, the link having a distal end for attachment to a seconc jaw, characterised in that the proximal end of the first arm is configured for attachment to an extraction device. a first arm having a proximal end, a distal end for attachment to a first jaw, and a proximal end, a distal end for attachment to a first jaw, and a second arm having a proximal end and a distal end, wherein the first arm further comprises: an adjustment mechanism that includes: an adjuster, and a lever having a proximal end engaged with the adjuster and a distal end pivotably connected to the second arm; and an adjuster, and a lever having a proximal end engaged with the adjuster and a distal end pivotably connected to the second arm; and wherein the implant extractor further comprises a link pivotably connected to the first and second arms, the link having a distal end for attachment to a seconc jaw, characterised in that the proximal end of the first arm is configured for attachment to an extraction device.
A sealing member comprising: a first longitudinal end and a second longitudinal end opposite to the first longitudinal end, a lip portion comprising an upper leg and a lower leg, each disposed at an angle to a longitudinal axis of the sealing member to substantially form a V shape at the first longitudinal end of the sealing member, and characterized by: a ridge portion comprising an upper ridge and a lower ridge, each disposed at the second longitudinal end, and an upper cutout portion disposed adjacent to the upper ridge and a lower cutout portion disposed adjacent to the lower ridge; wherein the lip portion is configured to be disposed between a lid and a cooking chamber of a cooking apparatus, the lower leg of the lip portion is configured to be compressed toward the upper leg of the lip portion when the lid is closed to create a seal between the cooking chamber and the lid, and the upper cutout portion is configured to accommodate a portion of a fastener securing a lid liner to the lid. a first longitudinal end and a second longitudinal end opposite to the first longitudinal end, a lip portion comprising an upper leg and a lower leg, each disposed at an angle to a longitudinal axis of the sealing member to substantially form a V shape at the first longitudinal end of the sealing member, and characterized by: a ridge portion comprising an upper ridge and a lower ridge, each disposed at the second longitudinal end, and an upper cutout portion disposed adjacent to the upper ridge and a lower cutout portion disposed adjacent to the lower ridge; wherein the lip portion is configured to be disposed between a lid and a cooking chamber of a cooking apparatus, the lower leg of the lip portion is configured to be compressed toward the upper leg of the lip portion when the lid is closed to create a seal between the cooking chamber and the lid, and the upper cutout portion is configured to accommodate a portion of a fastener securing a lid liner to the lid. a ridge portion comprising an upper ridge and a lower ridge, each disposed at the second longitudinal end, and an upper cutout portion disposed adjacent to the upper ridge and a lower cutout portion disposed adjacent to the lower ridge; wherein the lip portion is configured to be disposed between a lid and a cooking chamber of a cooking apparatus, the lower leg of the lip portion is configured to be compressed toward the upper leg of the lip portion when the lid is closed to create a seal between the cooking chamber and the lid, and the upper cutout portion is configured to accommodate a portion of a fastener securing a lid liner to the lid.
A method of reducing the immune response to an epitope while retaining overall protein structure, comprising: a. identifying surface-exposed amino acids of an epitope having high log odds ratio propensity scale (LODrps) value >0.3 and b. replacing at least one of the surface-exposed amino acids having a high LODrps value >0.3 with an amino acid having a low LODrps value wherein the LODrps values are shown in table 1. a. identifying surface-exposed amino acids of an epitope having high log odds ratio propensity scale (LODrps) value >0.3 and b. replacing at least one of the surface-exposed amino acids having a high LODrps value >0.3 with an amino acid having a low LODrps value wherein the LODrps values are shown in table 1.
A portable computer comprising: a computer body, a lid with an inner face having a first liquid crystal display disposed therein; a hinge connecting the computer body to the lid, wherein the lid can be folded onto the computer body and opened away from the computer body, and the lid has an upper edge, a first lateral edge, and a second lateral edge; a second liquid crystal display which can be accommodated in the computer body and can be pulled out sideways therefrom, characterised in that said second liquid crystal display is separable from the computer body and detachably attachable to the lid by a fixing means provided on one of the upper edge, the first lateral edge, or the second lateral edge, such that the first liquid crystal display and the second liquid crystal display extend in a single common plane. a computer body, a lid with an inner face having a first liquid crystal display disposed therein; a hinge connecting the computer body to the lid, wherein the lid can be folded onto the computer body and opened away from the computer body, and the lid has an upper edge, a first lateral edge, and a second lateral edge; a second liquid crystal display which can be accommodated in the computer body and can be pulled out sideways therefrom, characterised in that said second liquid crystal display is separable from the computer body and detachably attachable to the lid by a fixing means provided on one of the upper edge, the first lateral edge, or the second lateral edge, such that the first liquid crystal display and the second liquid crystal display extend in a single common plane.
A vascular closure system, comprising: a suture; an anchor assembly comprising: a first anchor portion having a plurality of petal members (246A-D) automatically expandable from a retracted position for delivery through a vessel puncture in a vessel, and an expanded position when deployed within the vessel, wherein the plurality of petal members (246A-D) extend proximally when in the retracted position; characterized in that: the plurality of petal members (246A-D) include stiffening members including at least one rib; and the anchor assembly further comprises a second anchor portion connected to the suture and positioned distal of the first anchor portion within the vessel; wherein withdrawing the suture pulls the second anchor portion against the first anchor portion to contact the first anchor portion against an inner surface of the vessel adjacent to the vessel puncture. a suture; an anchor assembly comprising: a first anchor portion having a plurality of petal members (246A-D) automatically expandable from a retracted position for delivery through a vessel puncture in a vessel, and an expanded position when deployed within the vessel, wherein the plurality of petal members (246A-D) extend proximally when in the retracted position; characterized in that: the plurality of petal members (246A-D) include stiffening members including at least one rib; and the anchor assembly further comprises a second anchor portion connected to the suture and positioned distal of the first anchor portion within the vessel; a first anchor portion having a plurality of petal members (246A-D) automatically expandable from a retracted position for delivery through a vessel puncture in a vessel, and an expanded position when deployed within the vessel, wherein the plurality of petal members (246A-D) extend proximally when in the retracted position; characterized in that: the plurality of petal members (246A-D) include stiffening members including at least one rib; and the anchor assembly further comprises a second anchor portion connected to the suture and positioned distal of the first anchor portion within the vessel; the plurality of petal members (246A-D) include stiffening members including at least one rib; and the anchor assembly further comprises a second anchor portion connected to the suture and positioned distal of the first anchor portion within the vessel; wherein withdrawing the suture pulls the second anchor portion against the first anchor portion to contact the first anchor portion against an inner surface of the vessel adjacent to the vessel puncture.
A controller for a multi-roll printer configured to print on at least a first roll of a medium and a second roll of a medium at the same time, the controller comprising: a data interface configured to receive print jobs to be executed by the multi-roll printer, each print job comprising at least one image to be printed; a display configured to display a graphical user interface, GUI, with graphical representations of the print jobs received by the data interface, wherein a first region, a second region and a third region are defined within the GUI; a user interface which allows a user to assign the graphical representation of any print job of the received print jobs to any one of the first, second and third region (A1, A2, A3) of the GUI; an assignment logic configured to assign all images of a print job to the first roll when the respective graphical representation of that print job has been assigned by the user to the first region; wherein the assignment logic is further configured to assign all images of a print job to the second roll when the respective graphical representation of that print job has been assigned by the user to the second region; and wherein the assignment logic is further configured to determine, for each image of a print job whose graphical representation has been assigned to the third region by the user, one of the rolls (R1, R2) of the multi-roll printer and to assign each image to the respective roll (R1, R2) chosen for that image. a data interface configured to receive print jobs to be executed by the multi-roll printer, each print job comprising at least one image to be printed; a display configured to display a graphical user interface, GUI, with graphical representations of the print jobs received by the data interface, wherein a first region, a second region and a third region are defined within the GUI; a user interface which allows a user to assign the graphical representation of any print job of the received print jobs to any one of the first, second and third region (A1, A2, A3) of the GUI; an assignment logic configured to assign all images of a print job to the first roll when the respective graphical representation of that print job has been assigned by the user to the first region; wherein the assignment logic is further configured to assign all images of a print job to the second roll when the respective graphical representation of that print job has been assigned by the user to the second region; and wherein the assignment logic is further configured to determine, for each image of a print job whose graphical representation has been assigned to the third region by the user, one of the rolls (R1, R2) of the multi-roll printer and to assign each image to the respective roll (R1, R2) chosen for that image.
Feedthrough for an electrical storage device having at least one conductor and a glass or glass-ceramic material as well as a base body, in particular in the form of a preferably disk-shaped metal part having a thickness, wherein the base body has at least one opening through which the at least one conductor is passed in the glass or glass-ceramic material, wherein the base body comprises a light metal or AlSiC, wherein AlSiC is an Al-infiltrated SiC matrix, and glass or glass-ceramic material is selected such that the fusion temperature of the glass or glass-ceramic material with the light metal or AlSiC is below the fusion temperature of the light metal or AlSiC of the base body, characterized in that the opening passes through the entire thickness of the base body and a cover glass or a plastic layer is applied to the glass or glass-ceramic material, wherein the cover glass or the plastic layer increases the chemical resistance of the glass or glass-ceramic material and in the case of glass has a sufficient chemical resistance to acids and/or to water, wherein the cover glass has a fusion temperature which is lower than the fusion temperature of the base body.
An antibody-drug conjugate comprising a cytotoxic drug conjugated to the N-terminal amino acid residue of the heavy chain or light chain of an antibody, wherein the cytotoxic drug is conjugated to the N-terminal α-amine group of the heavy chain or light chain of the antibody, and the cytotoxic drug is conjugated to the antibody by a linker having a reactive aldehyde group through reductive alkylation.
A misfire determination device of an engine in which explosion occurs at unequal intervals, the engine including a plurality of cylinders and a crankshaft which is angularly displaced at a different angle between expansion strokes, the misfire determination device being configured to calculate a generated torque correlation amount correlated with torque generated in the crankshaft, based on an angular position signal of the crankshaft, and perform misfire determination, based on an average value of the generated torque correlation amount in an interval less than one cycle of the engine, at an angular position of the crankshaft which is different from an angular position of the crankshaft at an ignition timing, wherein the angular position of the crankshaft at which the misfire determination is performed is set for each of the plurality of cylinders for which the misfire determination is to be performed, and angular positions corresponding to the plurality of cylinders, respectively, have values different from each other.
A dental capsule for mixing and dispensing dental materials comprised of at least three components, the capsule comprising: a plunger; a first open-ended liquid receptacle adapted to receive the plunger; a second open-ended liquid receptacle adapted to receive the first liquid receptacle; wherein the plunger has a forwardly projecting protrusion adapted to sequentially pierce a weakened portion of the first liquid receptacle and a weakened portion of the second liquid receptacle; and a main body with a proximal end, a distal end, a chamber open at the proximal end and an aperture in the distal end; wherein the chamber is adapted to receive the second liquid receptacle; and wherein the dental capsule is adapted to mix various components of the dental materials and form a dental paste for dispensing. a plunger; a first open-ended liquid receptacle adapted to receive the plunger; a second open-ended liquid receptacle adapted to receive the first liquid receptacle; wherein the plunger has a forwardly projecting protrusion adapted to sequentially pierce a weakened portion of the first liquid receptacle and a weakened portion of the second liquid receptacle; and a main body with a proximal end, a distal end, a chamber open at the proximal end and an aperture in the distal end; wherein the chamber is adapted to receive the second liquid receptacle; and wherein the dental capsule is adapted to mix various components of the dental materials and form a dental paste for dispensing.
A method of providing a light reflecting member having a light reflecting surface, the method comprising: forming a bundle of at least five longitudinal members having surfaces exposed at an end of the bundle, the forming comprising affixing together the longitudinal members to prevent relative movement; polishing collectively the exposed surfaces of the longitudinal members at the end of the bundle; coating the polished surfaces of the longitudinal members with a light reflecting film; and separating the bundle to provide each longitudinal member as a light reflecting member having the coated surface as a light reflecting surface; wherein the longitudinal members are made of metal, characterised in that: the light reflecting film comprises a material selected from the group consisting of aluminum, silver, and gold. forming a bundle of at least five longitudinal members having surfaces exposed at an end of the bundle, the forming comprising affixing together the longitudinal members to prevent relative movement; polishing collectively the exposed surfaces of the longitudinal members at the end of the bundle; coating the polished surfaces of the longitudinal members with a light reflecting film; and separating the bundle to provide each longitudinal member as a light reflecting member having the coated surface as a light reflecting surface; wherein the longitudinal members are made of metal, characterised in that: the light reflecting film comprises a material selected from the group consisting of aluminum, silver, and gold.