mhurhangee/ep-ind-claims huggingface dataset:
A method for the detection of a target RNA sequence in a sample comprising the steps of: (a) contacting single-stranded RNA (ssRNA) molecules present in a sample with a labelled oligonucleotide containing a sequence substantially complementary to a region of the target RNA under hybridisation conditions to provide a mixture of RNA-oligonucleotide duplexes wherein the RNA-oligonucleotide duplexes comprise the target RNA annealed to the labelled oligonucleotide; (b) maintaining the mixture of step (a) with an RNA-dependent RNA polymerase (RdRp) under RNA polymerisation conditions in the absence of a primer wherein said RdRp has an RNA-oligonucleotide duplex separation activity and is capable of synthesising a complementary RNA strand on a single-stranded RNA template without requiring an RNA duplex for initiation of polymerisation such that the RdRp polymerises an RNA strand complementary to the ssRNA in the sample and releases the labelled oligonucleotide; and (c) detecting and/or measuring the signal generated by the released labelled oligonucleotide. (a) contacting single-stranded RNA (ssRNA) molecules present in a sample with a labelled oligonucleotide containing a sequence substantially complementary to a region of the target RNA under hybridisation conditions to provide a mixture of RNA-oligonucleotide duplexes wherein the RNA-oligonucleotide duplexes comprise the target RNA annealed to the labelled oligonucleotide; (b) maintaining the mixture of step (a) with an RNA-dependent RNA polymerase (RdRp) under RNA polymerisation conditions in the absence of a primer wherein said RdRp has an RNA-oligonucleotide duplex separation activity and is capable of synthesising a complementary RNA strand on a single-stranded RNA template without requiring an RNA duplex for initiation of polymerisation such that the RdRp polymerises an RNA strand complementary to the ssRNA in the sample and releases the labelled oligonucleotide; and (c) detecting and/or measuring the signal generated by the released labelled oligonucleotide.
An electrode assembly (10, 110, 210, 310) for receiving a nerve; the electrode assembly (10, 110, 210, 310) comprising: a cuff (14, 114, 214, 314) including a body (16, 116, 216, 316) having a first end (18a, 218a, 318a), a second end (18b, 218b, 318b), and defining a first channel (20, 220, 320) configured to receive the nerve, the cuff (14, 114, 214, 314) further including first and second ears (22, 24, 122, 124, 222, 224, 322, 324) extending radially outwardly from the body (16, 116, 216, 316); wherein a second channel (50, 150, 350a, 350b) is formed in the first ear (22, 122, 222, 322); wherein the body (16, 116, 216, 316) further defines a gap (36, 236, 336) and a width of the gap (36, 236, 336) is variable and configured to support a degree fixation to the nerve that is dissected less than 360 degrees; an electrode (12, 312a, 312b) supported by and positioned within the second channel (50, 150, 350a, 350b); and a lead wire assembly (60, 360a, 360b) interconnected to the electrode (12, 312a, 312b) and extending within the second channel (50, 150, 350a, 350b), wherein the cuff (14, 114, 214, 314) includes open and closed positions in which the width of the gap (36, 236, 336) formed by the body (16, 116, 216, 316) and also a width of the channel (20, 220, 320) of the body (16, 116, 216, 316) are varied via flexing of the cuff (14, 114, 214, 314) at a hinge segment (38, 128, 238, 338), and the first channel (20, 220, 320) in the closed position has an annular shape. a cuff (14, 114, 214, 314) including a body (16, 116, 216, 316) having a first end (18a, 218a, 318a), a second end (18b, 218b, 318b), and defining a first channel (20, 220, 320) configured to receive the nerve, the cuff (14, 114, 214, 314) further including first and second ears (22, 24, 122, 124, 222, 224, 322, 324) extending radially outwardly from the body (16, 116, 216, 316); wherein a second channel (50, 150, 350a, 350b) is formed in the first ear (22, 122, 222, 322); wherein the body (16, 116, 216, 316) further defines a gap (36, 236, 336) and a width of the gap (36, 236, 336) is variable and configured to support a degree fixation to the nerve that is dissected less than 360 degrees; an electrode (12, 312a, 312b) supported by and positioned within the second channel (50, 150, 350a, 350b); and a lead wire assembly (60, 360a, 360b) interconnected to the electrode (12, 312a, 312b) and extending within the second channel (50, 150, 350a, 350b), wherein the cuff (14, 114, 214, 314) includes open and closed positions in which the width of the gap (36, 236, 336) formed by the body (16, 116, 216, 316) and also a width of the channel (20, 220, 320) of the body (16, 116, 216, 316) are varied via flexing of the cuff (14, 114, 214, 314) at a hinge segment (38, 128, 238, 338), and the first channel (20, 220, 320) in the closed position has an annular shape.
A method for waterproofing a wall having a wall opening through which a water combination extends, the method comprising: fitting a sleeve including a resiliently flexible collar which extends radially inwards to the water combination, the collar being expanded to fit about the water combination; sealing a coupling element, separate from the sleeve and including a flange, to the sleeve; sealing the flange of the coupling element to the wall; adjusting the sleeve by trimming or cutting the sleeve to be substantially flush with the wall. fitting a sleeve including a resiliently flexible collar which extends radially inwards to the water combination, the collar being expanded to fit about the water combination; sealing a coupling element, separate from the sleeve and including a flange, to the sleeve; sealing the flange of the coupling element to the wall; adjusting the sleeve by trimming or cutting the sleeve to be substantially flush with the wall.
Method for monitoring a battery that has an associated number of sensors (20, 22, 24), wherein the sensors (20, 22, 24) are connected in series with one another and to a controller via a data line, wherein at least one of the sensors (20, 22, 24) puts at least one respective data word onto the data line for transmission to the controller, characterized in that the data words reach the sensors (20, 22, 24) again via a return channel and can each be overwritten by the associated sensor (20, 22, 24).
Door (3, 4) for a household refrigeration appliance, with a plate-like base body (5, 9), and with a separate cover plate (6, 10) to the base body (5, 9), which is arranged on the base body (5, 9) in a non-destructively detachable manner and which on the front side covers an outer side (8, 14) of the base body (5, 9) at least in part, wherein a separate filler element which can be compressed is arranged on an inner side of a front plate (7, 11) of the cover plate (6, 10), which is elastically deformable in a direction perpendicular to its main extension plane, characterised in that the filler element is formed by means of a flat body and that the flat filler element is connected to the front plate (7, 11) of the cover with a material bond.
Waste collection system for processing waste sacks in an at least partially automated manner, comprising - a filling arrangement with - a receiving device, in particular a frame, for receiving and securing a waste sack; - a clamping arrangement for spreading open the waste sack in an automated manner in a filling position of the filling arrangement; and - a sealing device for sealing the waste sack in an automated manner; wherein - the waste collection system has a collection position, which is different from the filling position, for collecting sealed waste sacks; - and wherein the filling arrangement has a transfer mechanism for transporting the waste sack from the filling position to the collection position, characterized in that the waste collection system has a collecting robot, by means of which waste sacks located in the collection position can be collected in an automated manner. - a filling arrangement with - a receiving device, in particular a frame, for receiving and securing a waste sack; - a clamping arrangement for spreading open the waste sack in an automated manner in a filling position of the filling arrangement; and - a sealing device for sealing the waste sack in an automated manner; wherein - the waste collection system has a collection position, which is different from the filling position, for collecting sealed waste sacks; - and wherein the filling arrangement has a transfer mechanism for transporting the waste sack from the filling position to the collection position,
A clutched device for association with an engine, comprising: an input member that is rotatable via an endless drive member that is driven by the engine; an output member; a one-way clutch that can operatively connect the input member to the output member; and a motor including a stator and a rotor, wherein the rotor is connected for rotation with a portion of the one-way clutch, characterized in that the stator is operable to apply a first magnetic driving force to cause movement of the portion of the one-way clutch in a first rotational direction to increase a force of engagement between the input and output members, wherein the stator is operable to apply a second magnetic driving force to cause movement of the portion of the one-way clutch to disengage the input and output members from each other. an input member that is rotatable via an endless drive member that is driven by the engine; an output member; a one-way clutch that can operatively connect the input member to the output member; and a motor including a stator and a rotor, wherein the rotor is connected for rotation with a portion of the one-way clutch,
Dish washer with a vat for receiving dishes, with a cooling device for cooling at least one wall of the vat and with a controller for controlling a cleaning process comprising a cleaning phase and a drying phase, wherein the controller is adapted to heat the vat for drying the dishes and to cool the wall of the vat by the cooling device during the drying phase, characterized in that the controller is adapted to control the cooling device during the drying phase such that a center temperature of the vat lies between 1° and 10°C, in particular 2° - 6°C, above a temperature of the wall, wherein the controller is adapted to increase a cooler power of the cooling device in several steps or continuously during the drying phase, wherein a length of the drying phase is at least 10 minutes, in particular at least 20 minutes, wherein the drying phase is understood as the time range in which the cooler power increases in several steps or continuously and the temperature of the wall lies below the center temperature by the mentioned difference.
An opioid antagonist composition comprising an opioid antagonist dispersed in a melt-extruded matrix, wherein the matrix comprises one or more of a pharmaceutically acceptable hydrophobic material and renders the antagonist substantially non-releasable when the dosage form is administered intact such that the ratio of the amount of antagonist released from said dosage form after tampering, to the amount of said antagonist released from said intact dosage form is about 4:1 or greater, based on the in-vitro dissolution at 1 hour of said dosage form in 900 ml Simulated Gastric Fluid using a USP Type II (paddle) apparatus at 75 rpm at 37 degrees C.
A method for preparing a high-compactness bonded rare earth permanent magnet having a density of 6.2~7.0 g/cm 3, wherein, raw materials of the high-compactness bonded rare earth permanent magnet comprise, in mass percentage: a thermosetting resin 0.1-1.6 wt%, a lubricant 0.05-0.8 wt%, a coupling agent 0-1.0 wt%, and the rest being rare earth permanent magnetic powder; and the method comprises: mixing the rare earth permanent magnetic powder after crystallization treatment with a solution in which the thermosetting resin and the coupling agent are dissolved to obtain a mixture, drying the mixture after sealing and stirring, and obtaining a magnetic powder complex after crushing; mixing the magnetic powder complex with the lubricant to obtain a clinker; characterized in that the method further comprises: filling the clinker into a mold that is preheated to a temperature of 40~120 °C for preheating the clinker to 40~120 °C, compressing and molding at an unit compressing force of 1.2~5.0 GPa for 0.3~10 s, demolding to obtain a green body with a density of 6.2~7.1 g/cm 3, heating the green body at 120~200 °C for 1~3 h to obtain a rough blank, and conducting precision machining on the rough blank. raw materials of the high-compactness bonded rare earth permanent magnet comprise, in mass percentage: a thermosetting resin 0.1-1.6 wt%, a lubricant 0.05-0.8 wt%, a coupling agent 0-1.0 wt%, and the rest being rare earth permanent magnetic powder; and the method comprises: mixing the rare earth permanent magnetic powder after crystallization treatment with a solution in which the thermosetting resin and the coupling agent are dissolved to obtain a mixture, drying the mixture after sealing and stirring, and obtaining a magnetic powder complex after crushing; mixing the magnetic powder complex with the lubricant to obtain a clinker; characterized in that the method further comprises: filling the clinker into a mold that is preheated to a temperature of 40~120 °C for preheating the clinker to 40~120 °C, compressing and molding at an unit compressing force of 1.2~5.0 GPa for 0.3~10 s, demolding to obtain a green body with a density of 6.2~7.1 g/cm 3, heating the green body at 120~200 °C for 1~3 h to obtain a rough blank, and conducting precision machining on the rough blank. mixing the rare earth permanent magnetic powder after crystallization treatment with a solution in which the thermosetting resin and the coupling agent are dissolved to obtain a mixture, drying the mixture after sealing and stirring, and obtaining a magnetic powder complex after crushing; mixing the magnetic powder complex with the lubricant to obtain a clinker; characterized in that the method further comprises: filling the clinker into a mold that is preheated to a temperature of 40~120 °C for preheating the clinker to 40~120 °C, compressing and molding at an unit compressing force of 1.2~5.0 GPa for 0.3~10 s, demolding to obtain a green body with a density of 6.2~7.1 g/cm 3, heating the green body at 120~200 °C for 1~3 h to obtain a rough blank, and conducting precision machining on the rough blank.
Device of a chair for a chairlift which has a pivotable protection means, such as a safety bar or a weather protection hood, wherein the device comprises an energy accumulator which can be arranged between the protection means and a frame of the chair, characterized in that, during closing of the protection means, the energy accumulator can only be tensioned when the protection means is in the region of its end position by a pressure piece that is movable between a first position, in which it is at a distance from a mating surface and the energy accumulator is relaxed, and a second position, in which it bears against the mating surface and the energy accumulator is tensioned.
A material for molding an organ model for exercising an operation, or for molding an organ model for checking the sharpness of an excision implement for an operation, the material comprising an aqueous gel which comprises a polyvinyl alcohol having an average degree of polymerization of 300 to 3500 and a degree of saponification of not less than 90 % by mole, and silica particles, wherein the amount of silica particles is 0.01 to 50 parts by weight based on 100 parts by weight of the polyvinyl alcohol.
Aircraft stabilizer (15; 17) comprising a leading edge (41, 61), a torsion box (43, 63) and a trailing edge (42, 62); - the leading edge (41; 61) being configured with an aerodynamic shape suitable to promote a laminar flow on its surface; - the lateral skins (45a, 45b; 65a, 65b) of the torsion box (43; 63) including joggled areas (53a, 53b; 73a, 73b) as attachment areas of the leading edge (41; 61); wherein: - the joggled areas (53a, 53b; 73a, 73b) are arranged in a rearward position with respect to the forward most spar of the aircraft stabilizer (15; 17), characterised in that - the torsion box comprises a rounded front spar, a rear spar and intermediate spars and their lateral skins (65a, 65b) include recessed areas (70a, 70b) extending from at least the first intermediate spar to the rounded front spar to allow the accommodation of the leading edge over them; - the joggled areas (73a, 73b) are arranged in said recessed areas (70a, 70b) in a rearward position with respect to the rounded front spar. - the leading edge (41; 61) being configured with an aerodynamic shape suitable to promote a laminar flow on its surface; - the lateral skins (45a, 45b; 65a, 65b) of the torsion box (43; 63) including joggled areas (53a, 53b; 73a, 73b) as attachment areas of the leading edge (41; 61); wherein: - the joggled areas (53a, 53b; 73a, 73b) are arranged in a rearward position with respect to the forward most spar of the aircraft stabilizer (15; 17), characterised in that - the torsion box comprises a rounded front spar, a rear spar and intermediate spars and their lateral skins (65a, 65b) include recessed areas (70a, 70b) extending from at least the first intermediate spar to the rounded front spar to allow the accommodation of the leading edge over them; - the joggled areas (73a, 73b) are arranged in said recessed areas (70a, 70b) in a rearward position with respect to the rounded front spar.
An ultrasonic device for transversely manipulating drug delivery carriers, comprising: a driving unit; and a transducer electrically connected to the driving unit and having a piezoelectric sheet in a curved shape, wherein the piezoelectric sheet comprises a plurality of channels (1042a, 1042b, 1042c, 1042d), characterised in that a phase difference is generated between every two of the channels (1042a, 1042b, 1042c, 1042d) by the driving unit for producing an acoustic vortex. a driving unit; and a transducer electrically connected to the driving unit and having a piezoelectric sheet in a curved shape, wherein the piezoelectric sheet comprises a plurality of channels (1042a, 1042b, 1042c, 1042d), characterised in that a phase difference is generated between every two of the channels (1042a, 1042b, 1042c, 1042d) by the driving unit for producing an acoustic vortex.
A method of calibrating apparatus comprising a measurement probe mounted on a machine, the machine being arranged to capture machine position data (x,y,z;70;80) indicative of the position of the measurement probe relative to an artefact located within the working area of the machine, the measurement probe being an analogue or scanning probe having a deflectable stylus arranged to capture probe data (a,b,c;72;82) indicative of the position of a surface relative to the measurement probe, the method comprising the step of; (i) moving the measurement probe at a known speed relative to the artefact whilst capturing probe data (a,b,c;72;82) and machine position data (x,y,z;70;80), the measurement probe being moved along a path that enables the capture of probe data (a,b,c;72;82) indicative of the position of at least one point on the surface of the artefact relative to the measurement probe, the path also including at least one change in the direction of probe movement that can be identified from the machine position data (x,y,z;70;80) and the probe data (a,b,c;72;82); characterised in that the method further comprises the step of(ii) comparing the machine position data (x,y,z;70;80) and probe data (a,b,c;72;82) captured during the scan of step (i) and determining the relative time delay (Δt) in capturing machine position data (x,y,z;70;80) and probe data (a,b,c;72;82) from the at least one change in the direction of probe movement that can be identified from the machine position data (x,y,z;70;80) and the probe data(a,b,c;72;82). (i) moving the measurement probe at a known speed relative to the artefact whilst capturing probe data (a,b,c;72;82) and machine position data (x,y,z;70;80), the measurement probe being moved along a path that enables the capture of probe data (a,b,c;72;82) indicative of the position of at least one point on the surface of the artefact relative to the measurement probe, the path also including at least one change in the direction of probe movement that can be identified from the machine position data (x,y,z;70;80) and the probe data (a,b,c;72;82);
Power semiconductor module having a substrate and power semiconductor components arranged on the substrate and connected to the substrate, wherein the power semiconductor module has an electrically conductive connecting device formed in one piece, wherein the connecting device has a flat first and a flat second connection region (19, 20) and an elastic region arranged between the first and second connection regions (19, 20), wherein the elastic region has strip-like first and second shaped elements (17, 18), which are angled over in opposite directions relative to each other and are arranged alternately, wherein the first connection region is connected to the substrate, wherein the connecting device connects the substrate electrically conductively to an electrically conductive load-current-carrying element, wherein the second connection region is connected to the load-current-carrying element.
A strap member for use in securing a mask to the head of a patient, the strap member comprising: a strap portion formed from a first material, the first material comprising a silicone material, wherein the strap portion comprises a first side and an opposite second side; and a breathability enhancing element associated with the strap portion, wherein the breathability enhancing element comprises a second material different from the first material that is disposed on the second side of the strap portion, characterized in that the strap portion comprises a number of apertures extending between the first and second sides, wherein portions of the second material extend through each aperture of the number of apertures of the strap portion. a strap portion formed from a first material, the first material comprising a silicone material, wherein the strap portion comprises a first side and an opposite second side; and a breathability enhancing element associated with the strap portion, wherein the breathability enhancing element comprises a second material different from the first material that is disposed on the second side of the strap portion, characterized in that the strap portion comprises a number of apertures extending between the first and second sides, wherein portions of the second material extend through each aperture of the number of apertures of the strap portion.
Guide vane of a gas turbine engine, in particular of an aircraft engine, which has a pressure-side wall, a suction-side wall, a guide vane root, a guide vane tip, a guide vane leading edge area, a guide vane trailing edge area that is facing away from the guide vane leading edge area, and at least one channel for conducting a fluid to be cooled arranged in an internal space of the guide vane (11, 19), wherein during operation of the gas turbine engine a cooling air flow (16, 17) of a cooling system impinges on the guide vane leading edge area from the outside, wherein a first part (16.1) of the cooling air flow flows around an outer side of the pressure-side wall, and a second part (16.2) of the cooling air flow flows around an outer side of the suction-side wall, characterized in that a third part (16.3) of the cooling air flow flows through the internal space, wherein the third part (16.3) of the cooling air flow flows around the channel with the fluid to be cooled.