A compound of Formula: or an enantiomer, diastereomer, stereoisomer, or pharmaceutically acceptable salt thereof, wherein: the Linker is wherein p1 is an integer selected from 0 to 12; p2 is an integer selected from 0 to 12; p3 is an integer selected from 0 to 6; each W is independently absent, CH 2, O, S, NH, or NR 10; Z is absent, CH 2, O, NH, NR 10, C (CH 2) 0-3, or NHC (CH 2) 0-3; each R 10 is independently H or C 1 -C 3 alkyl; Q is absent or CH 2 C NH; and wherein the Linker is covalently bonded to the Degron via the next to Q; the Degron is each R 17 is independently C 1 -C 3 alkyl; q' is 0, 1, 2, 3 or 4; and R 18 is H or C 1 -C 3 alkyl, R 19 is C 1 -C 3 alkyl, wherein the Degron is covalently bonded to the Linker via A is phenyl or pyridinyl; X is CH, C(C 1 -C 3) alkyl, or N; R 1 is H or (C 1 -C 3) alkyl; R 2 is (C 6 -C 10) aryl, or heteroaryl comprising one or two 5- to 7-membered rings and 1-4 heteroatoms selected from N, O, and S, wherein the aryl and heteroaryl are each optionally substituted with one or more R 4; each R 4 is independently selected from (C 1 -C 4) alkyl, (C 1 -C 4) haloalkyl, (C 1 -C 4) alkoxy, (C 1 -C 4) haloalkoxy, halogen, NO 2, OH, CN, C R 6, C OR 6, C NR 6 R 7, NR 6 R 7, (C 3 -C 7) cycloalkyl, heterocyclyl comprising a 5- to 7-membered ring and 1-3 heteroatoms selected from N, O, and S, (C 6 -C 10) aryl, and heteroaryl comprising one or two 5- to 7-membered rings and 1-4 heteroatoms selected from N, O, and S, wherein the alkyl, cycloalkyl, heterocyclyl, aryl, and heteroaryl are each optionally substituted with one or more R 5; each R 5 is independently selected from (C 1 -C 4) alkyl, (C 1 -C 4) haloalkyl, (C 1 -C 4) alkoxy, (C 1 -C 4) haloalkoxy, halogen, NO 2, OH, and CN; each R 6 is independently H or (C 1 -C 3) alkyl; each R 7 is independently H or (C 1 -C 3) alkyl; R 3 is (C 1 -C 3) alkyl or X 2 is N or CR 8; R 8 is H, (C 1 -C 4) alkyl, (C 1 -C 4) haloalkyl, (C 1 -C 4) alkoxy, (C 1 -C 4) haloalkoxy, halogen, NO 2, NH 2, OH, or CN; each R 9 is independently selected from (C 1 -C 4) alkyl, (C 1 -C 4) haloalkyl, (C 1 -C 4) alkoxy, (C 1 -C 4) haloalkoxy, halogen, NO 2, NH 2, OH, and CN; n is 0 or 1; and p is 0, 1, 2, or 3. p1 is an integer selected from 0 to 12; p2 is an integer selected from 0 to 12; p3 is an integer selected from 0 to 6; each W is independently absent, CH 2, O, S, NH, or NR 10; Z is absent, CH 2, O, NH, NR 10, C (CH 2) 0-3, or NHC (CH 2) 0-3; each R 10 is independently H or C 1 -C 3 alkyl; Q is absent or CH 2 C NH; and wherein the Linker is covalently bonded to the Degron via the next to Q; the Degron is each R 17 is independently C 1 -C 3 alkyl; q' is 0, 1, 2, 3 or 4; and R 18 is H or C 1 -C 3 alkyl, R 19 is C 1 -C 3 alkyl, wherein the Degron is covalently bonded to the Linker via A is phenyl or pyridinyl; X is CH, C(C 1 -C 3) alkyl, or N; R 1 is H or (C 1 -C 3) alkyl; R 2 is (C 6 -C 10) aryl, or heteroaryl comprising one or two 5- to 7-membered rings and 1-4 heteroatoms selected from N, O, and S, wherein the aryl and heteroaryl are each optionally substituted with one or more R 4; each R 4 is independently selected from (C 1 -C 4) alkyl, (C 1 -C 4) haloalkyl, (C 1 -C 4) alkoxy, (C 1 -C 4) haloalkoxy, halogen, NO 2, OH, CN, C R 6, C OR 6, C NR 6 R 7, NR 6 R 7, (C 3 -C 7) cycloalkyl, heterocyclyl comprising a 5- to 7-membered ring and 1-3 heteroatoms selected from N, O, and S, (C 6 -C 10) aryl, and heteroaryl comprising one or two 5- to 7-membered rings and 1-4 heteroatoms selected from N, O, and S, wherein the alkyl, cycloalkyl, heterocyclyl, aryl, and heteroaryl are each optionally substituted with one or more R 5; each R 5 is independently selected from (C 1 -C 4) alkyl, (C 1 -C 4) haloalkyl, (C 1 -C 4) alkoxy, (C 1 -C 4) haloalkoxy, halogen, NO 2, OH, and CN; each R 6 is independently H or (C 1 -C 3) alkyl; each R 7 is independently H or (C 1 -C 3) alkyl; R 3 is (C 1 -C 3) alkyl or X 2 is N or CR 8; R 8 is H, (C 1 -C 4) alkyl, (C 1 -C 4) haloalkyl, (C 1 -C 4) alkoxy, (C 1 -C 4) haloalkoxy, halogen, NO 2, NH 2, OH, or CN; each R 9 is independently selected from (C 1 -C 4) alkyl, (C 1 -C 4) haloalkyl, (C 1 -C 4) alkoxy, (C 1 -C 4) haloalkoxy, halogen, NO 2, NH 2, OH, and CN; n is 0 or 1; and p is 0, 1, 2, or 3.