A syringe assembly, comprising: a syringe barrel having an inside surface defining a chamber, a proximal end, and a distal end having an opening therethrough; a plunger assembly comprising an elongate plunger rod (42, 242) substantially disposed within the syringe barrel and a plunger head (50, 250) disposed on the plunger rod (42, 242) and slidably disposed within the syringe barrel, the plunger head (50, 250) separating the chamber of the syringe barrel into a proximal chamber adjacent the proximal end and a distal chamber adjacent the distal end, a conduit extending between the proximal chamber and the opening at the distal end of the syringe barrel, wherein a fluid is contained in the proximal chamber, and wherein the plunger assembly further comprises an actuator portion extending at least partially outside of the syringe barrel, the actuator portion comprising at least one flange (48a, 48b, 240) directly or indirectly connected with the plunger head to effect the movement of the plunger head (50, 250) within the syringe barrel, wherein the fluid contained within the proximal chamber is adapted to be expelled through the conduit and out of the outlet opening at the distal end of the syringe barrel upon movement of the plunger head (50, 250) toward the proximal end of the syringe barrel, and characterized in that the at least one flange (48a, 48b, 240) is positioned between the distal end and the proximal end of the syringe barrel, wherein movement of the plunger head (50, 250) toward the proximal end of the syringe barrel occurs based on conventional operation of expelling a fluid from a conventional syringe with a squeezing movement between a thumb and a forefinger such that the flange (48a, 48b, 240) moves along the external wall of the syringe barrel toward the proximal end of the syringe barrel causing at least a portion of the plunger rod (42, 242) to extend externally of the syringe barrel. a syringe barrel having an inside surface defining a chamber, a proximal end, and a distal end having an opening therethrough; a plunger assembly comprising an elongate plunger rod (42, 242) substantially disposed within the syringe barrel and a plunger head (50, 250) disposed on the plunger rod (42, 242) and slidably disposed within the syringe barrel, the plunger head (50, 250) separating the chamber of the syringe barrel into a proximal chamber adjacent the proximal end and a distal chamber adjacent the distal end, a conduit extending between the proximal chamber and the opening at the distal end of the syringe barrel, wherein a fluid is contained in the proximal chamber, and wherein the plunger assembly further comprises an actuator portion extending at least partially outside of the syringe barrel, the actuator portion comprising at least one flange (48a, 48b, 240) directly or indirectly connected with the plunger head to effect the movement of the plunger head (50, 250) within the syringe barrel, wherein the fluid contained within the proximal chamber is adapted to be expelled through the conduit and out of the outlet opening at the distal end of the syringe barrel upon movement of the plunger head (50, 250) toward the proximal end of the syringe barrel, and characterized in that the at least one flange (48a, 48b, 240) is positioned between the distal end and the proximal end of the syringe barrel, wherein movement of the plunger head (50, 250) toward the proximal end of the syringe barrel occurs based on conventional operation of expelling a fluid from a conventional syringe with a squeezing movement between a thumb and a forefinger such that the flange (48a, 48b, 240) moves along the external wall of the syringe barrel toward the proximal end of the syringe barrel causing at least a portion of the plunger rod (42, 242) to extend externally of the syringe barrel.