A neural interface for interfacing with a target vessel, comprising: a first end portion, a second end portion and a center portion positioned between the first end portion and the second end portion, wherein the first end portion includes at least a first electrode and the second end portion includes at least a second electrode, wherein the first end portion, the second end portion and the center portion are each formed of a flexible material that is configured to enable each of the first end portion, the second end portion and the center portion to self-size to a surface of the target vessel when the neural interface is released at a position along the target vessel, and wherein neither the first end portion, the second end portion nor the center portion form a closed circumscribed circular arc around the target vessel at any point along a length of the target vessel; and a spinal portion configured to house electrical conductors for the first electrode and the second electrode, the spinal portion being connected to one or more of the first end portion, the center portion and the second end portion, wherein at least the first end portion is formed from a substantially opposing at least partially circular arc, wherein the at least partially circular arc includes a closed end attached to the spinal portion and an open end, wherein an opening is formed between the open end of the at least partially circular arc substantially opposite the spinal portion, wherein the open end includes an attribution opening configured to engage a deployment tool, further wherein application of pulling pressure on the deployment tool pulls the open end of the first end portion away from the spinal portion and enables the first end portion to be positioned around the target vessel, and wherein removal of the pulling pressure allows the first end portion to self-size to the surface of the target vessel. a first end portion, a second end portion and a center portion positioned between the first end portion and the second end portion, wherein the first end portion includes at least a first electrode and the second end portion includes at least a second electrode, wherein the first end portion, the second end portion and the center portion are each formed of a flexible material that is configured to enable each of the first end portion, the second end portion and the center portion to self-size to a surface of the target vessel when the neural interface is released at a position along the target vessel, and wherein neither the first end portion, the second end portion nor the center portion form a closed circumscribed circular arc around the target vessel at any point along a length of the target vessel; and a spinal portion configured to house electrical conductors for the first electrode and the second electrode, the spinal portion being connected to one or more of the first end portion, the center portion and the second end portion, wherein at least the first end portion is formed from a substantially opposing at least partially circular arc, wherein the at least partially circular arc includes a closed end attached to the spinal portion and an open end, wherein an opening is formed between the open end of the at least partially circular arc substantially opposite the spinal portion, wherein the open end includes an attribution opening configured to engage a deployment tool, further wherein application of pulling pressure on the deployment tool pulls the open end of the first end portion away from the spinal portion and enables the first end portion to be positioned around the target vessel, and wherein removal of the pulling pressure allows the first end portion to self-size to the surface of the target vessel.