An anchor assembly configured to be anchored to an anatomical location, the anchor assembly comprising: an anchor including an anchor body that defines an expandable portion, the expandable portion defining a direction of elongation, the anchor body defining a plurality of loops that define a respective plurality of openings that extend through the expandable portion and are spaced substantially along the direction of elongation, wherein the anchor body comprises a substrate that comprises an anchor body strand; and the anchor further including an actuation member that defines first and second actuation member ends (41, 43), the actuation member configured to receive an actuation force and, in response to the actuation force, actuate the expandable portion from a first configuration, wherein the expandable portion defines a first maximum thickness along a second direction that is angularly offset from the direction of elongation, to an expanded configuration, wherein the expandable portion defines a second maximum thickness along the second direction that is greater than the first maximum thickness, wherein the actuation member comprises an actuation strand, characterized in that the substrate of the anchor body is initially devoid of at least some of the openings and is at least one of braided, knitted and woven so as to define the openings, the anchor body defines an eyelet, wherein in the first configuration the plurality of loops are spaced proximally from the eyelet along the direction of elongation, the actuation member defines a fold disposed between the first and second ends (41, 43) such that the fold extends through the eyelet, and the first and second ends (41, 43) of the actuation member extend through at least two of the plurality of openings when the expandable portion is in the first configuration. an anchor including an anchor body that defines an expandable portion, the expandable portion defining a direction of elongation, the anchor body defining a plurality of loops that define a respective plurality of openings that extend through the expandable portion and are spaced substantially along the direction of elongation, wherein the anchor body comprises a substrate that comprises an anchor body strand; and the anchor further including an actuation member that defines first and second actuation member ends (41, 43), the actuation member configured to receive an actuation force and, in response to the actuation force, actuate the expandable portion from a first configuration, wherein the expandable portion defines a first maximum thickness along a second direction that is angularly offset from the direction of elongation, to an expanded configuration, wherein the expandable portion defines a second maximum thickness along the second direction that is greater than the first maximum thickness, wherein the actuation member comprises an actuation strand, characterized in that the substrate of the anchor body is initially devoid of at least some of the openings and is at least one of braided, knitted and woven so as to define the openings, the anchor body defines an eyelet, wherein in the first configuration the plurality of loops are spaced proximally from the eyelet along the direction of elongation, the actuation member defines a fold disposed between the first and second ends (41, 43) such that the fold extends through the eyelet, and the first and second ends (41, 43) of the actuation member extend through at least two of the plurality of openings when the expandable portion is in the first configuration.