mhurhangee/ep-ind-claims huggingface dataset:
A pharmaceutical composition comprising a recombinant Glial cell line-Derived Neurotrophic Factor (GDNF) polypeptide and a pharmaceutically acceptable carrier for use in treating an enteric neuropathy in a human subject by inducing enteric neurogenesis in an aganglionic or hypoganglionic segment of the distal colon, wherein the composition is administered into the distal colon of the subject rectally via enema at a dose of recombinant GDNF polypeptide of about 10 mg to about 15 mg per kg.
A system for treating pelvic organ prolapse, the system comprising: a shell that is insertable into a vagina, the shell having a convex exterior apex that is sized to contact an interior apical portion of the vagina; and an anchor having a proximal portion that is attachable to the apex of the shell and a distal portion that is provided with a tissue fixation device that is attachable to tissue exterior the vagina such that the anchor and the shell combine to support and elevate the interior apical portion of a vagina, characterized in that the shell is made of biodegradable material and includes a base opposite the apex and the shell has a wall thickness at the base that is less than a wall thickness of the apex. a shell that is insertable into a vagina, the shell having a convex exterior apex that is sized to contact an interior apical portion of the vagina; and an anchor having a proximal portion that is attachable to the apex of the shell and a distal portion that is provided with a tissue fixation device that is attachable to tissue exterior the vagina such that the anchor and the shell combine to support and elevate the interior apical portion of a vagina, characterized in that the shell is made of biodegradable material and includes a base opposite the apex and the shell has a wall thickness at the base that is less than a wall thickness of the apex.
A control method for an autonomous vehicle provided with an engine as a driving source, comprising: setting a required driving force in accordance with an intervehicular distance between an own vehicle and a preceding vehicle when there is the preceding vehicle in front of the own vehicle; predicting a behavior of the preceding vehicle from a situation in front of the preceding vehicle when there is the preceding vehicle; executing a sailing stop based on the required driving force and the predicted behavior of the preceding vehicle, the sailing stop causing the engine to stop automatically while the own vehicle is traveling at vehicle speed equal to or higher than given vehicle speed; and when future deceleration of the preceding vehicle is predicted as the behavior of the preceding vehicle in response to expansion of the intervehicular distance, prohibiting a cancellation of the sailing stop for the engine that is automatically stopped; characterized by prohibiting an execution of the sailing stop for the engine that is operating when future acceleration of the preceding vehicle is predicted as a behavior of the preceding vehicle in response to a reduction of the intervehicular distance. setting a required driving force in accordance with an intervehicular distance between an own vehicle and a preceding vehicle when there is the preceding vehicle in front of the own vehicle; predicting a behavior of the preceding vehicle from a situation in front of the preceding vehicle when there is the preceding vehicle; executing a sailing stop based on the required driving force and the predicted behavior of the preceding vehicle, the sailing stop causing the engine to stop automatically while the own vehicle is traveling at vehicle speed equal to or higher than given vehicle speed; and when future deceleration of the preceding vehicle is predicted as the behavior of the preceding vehicle in response to expansion of the intervehicular distance, prohibiting a cancellation of the sailing stop for the engine that is automatically stopped; characterized by prohibiting an execution of the sailing stop for the engine that is operating when future acceleration of the preceding vehicle is predicted as a behavior of the preceding vehicle in response to a reduction of the intervehicular distance.
A solid dispersion comprising the compound represented by Formula and a pharmaceutically acceptable polymer, which is hydroxypropyl methyl cellulose acetate succinate, wherein the solid dispersion comprises one or more anilinic substances each in an amount equal to or less than about 3.0% by weight based on the weight of the compound of Formula present in the solid dispersion.
A stand for an apparatus having a display unit, the stand capable of holding, when the apparatus is placed on a placement surface, an orientation of the apparatus, the stand comprising: a hinge portion; a body configured to be rotatable about the hinge portion and to hold an orientation of the apparatus; wherein, the hinge portion is disposed at an upper portion of the body and comprises a pair of hemispherical projections (14a, 14b) configured to be engaged with and supported by a corresponding axis support, such that the body is rotatable about the axis that extends between the pair of hemi-spherical projections (14a and 14b), and wherein the hinge portion is U-shaped comprising a central portion, two lateral portions perpendicular to and connected with the central portion at its opposed ends, and wherein the pair of hemispherical projections (14a, 14b) are provided on the two lateral portions projecting outward such that they extend along an axis parallel to the central portion. a hinge portion; a body configured to be rotatable about the hinge portion and to hold an orientation of the apparatus; wherein, the hinge portion is disposed at an upper portion of the body and comprises a pair of hemispherical projections (14a, 14b) configured to be engaged with and supported by a corresponding axis support, such that the body is rotatable about the axis that extends between the pair of hemi-spherical projections (14a and 14b), and wherein the hinge portion is U-shaped comprising a central portion, two lateral portions perpendicular to and connected with the central portion at its opposed ends, and wherein the pair of hemispherical projections (14a, 14b) are provided on the two lateral portions projecting outward such that they extend along an axis parallel to the central portion.
An ejector device for ejecting fluid onto a surface, the device comprising: a housing; a reservoir having a volume (V t) and containing or configured to receive a volume of fluid (V f) disposed within said housing; a fluid loading plate in fluid communication with said reservoir; and an ejector mechanism in fluid communication with said fluid loading plate; wherein said fluid loading plate includes a fluid reservoir interface for attaching to the reservoir, an ejector mechanism interface for attaching the fluid loading plate to the ejector mechanism, and one or more fluid channels for channeling fluid from the fluid reservoir interface to the ejector mechanism interface, the fluid loading plate being configured so as to be placed in a parallel arrangement with the ejector mechanism so as to form a capillary separation and generate capillary fluid flow between the fluid loading plate and the ejector mechanism at the rear surface of the ejector mechanism, said ejector mechanism being configured to eject a stream of droplets of said fluid through one or more openings, characterized in that the ejector mechanism is further configured to eject a stream of droplets having an average ejected droplet diameter greater than 15 microns (μm), with the stream of droplets having low entrained airflow so that the pressure of the stream of droplets onto the surface will be substantially imperceptible when sprayed against a human or animal body surface. a housing; a reservoir having a volume (V t) and containing or configured to receive a volume of fluid (V f) disposed within said housing; a fluid loading plate in fluid communication with said reservoir; and an ejector mechanism in fluid communication with said fluid loading plate; wherein said fluid loading plate includes a fluid reservoir interface for attaching to the reservoir, an ejector mechanism interface for attaching the fluid loading plate to the ejector mechanism, and one or more fluid channels for channeling fluid from the fluid reservoir interface to the ejector mechanism interface, the fluid loading plate being configured so as to be placed in a parallel arrangement with the ejector mechanism so as to form a capillary separation and generate capillary fluid flow between the fluid loading plate and the ejector mechanism at the rear surface of the ejector mechanism, said ejector mechanism being configured to eject a stream of droplets of said fluid through one or more openings, characterized in that the ejector mechanism is further configured to eject a stream of droplets having an average ejected droplet diameter greater than 15 microns (μm), with the stream of droplets having low entrained airflow so that the pressure of the stream of droplets onto the surface will be substantially imperceptible when sprayed against a human or animal body surface.
An N-terminally truncated Aβ oligomer comprising Aβ(X-42) fragments, wherein X is 10 to 24, wherein the oligomer is soluble in physiological saline, differs from fibrillar forms by its rather globular appearance, and is obtainable by a process comprising the steps of: (a) exposing a monomeric Aβ protein to a detergent to form an Aβ oligomer A which is soluble in physiological saline and differs from fibrillar forms by its rather globular appearance; (b) reducing the detergent action and continuing to incubate the Aβ oligomer A to form an Aβ oligomer B which is soluble in physiological saline and differs from fibrillar forms by its rather globular appearance; and (c) treating the Aβ oligomer B with protease, wherein the detergent is a compound of the formula R-X, in which the radical R is unbranched or branched alkyl having from 6 to 20 carbon atoms or unbranched or branched alkenyl having from 6 to 20 carbon atoms, and the radical X is an acidic group or salt thereof, and wherein the Aβ oligomer B has an apparent molecular weight of about 38 kDa and/or 48 kDa in SDS gel electrophoresis. (a) exposing a monomeric Aβ protein to a detergent to form an Aβ oligomer A which is soluble in physiological saline and differs from fibrillar forms by its rather globular appearance; (b) reducing the detergent action and continuing to incubate the Aβ oligomer A to form an Aβ oligomer B which is soluble in physiological saline and differs from fibrillar forms by its rather globular appearance; and (c) treating the Aβ oligomer B with protease,
An antibacterial formed article obtainable by melt-forming an antibacterial resin composition comprising a thermoplastic resin that contains a metal compound represented by the following formula, said metal compound being contained in an amount of 0.001 to 10 parts by weight per 100 parts by weight of said thermoplastic resin wherein M is any one of Ag, Cu, Zn, Co or Ni, and X is SO 2.
A mobile cooling device comprising a freezing chamber (2, 3, 4, 27), an eutectic cooling system arranged to cool the freezing chamber, a chilling chamber (5, 6, 29), and a separation wall (7, 30) between the chilling chamber and the freezing chamber, characterized in that the separation wall comprises a divider plate (8, 46) having a freezing side towards the freezing chamber, a chilling side towards the chilling chamber and forming a closed structure preventing exchange of air between the freezing chamber and the chilling chamber, the separation wall further comprising a freezing duct extending along the freezing side from a freezing inlet (25, 33) to a freezing outlet (26, 34) in the freezing chamber and a chilling duct extending along the chilling side from a chilling inlet (21, 38) to a chilling outlet (24, 39) in the chilling chamber, the chilling duct extending between the divider plate (8, 46) and a chilling duct inner wall (13, 45), a chilling syphon plate (19, 43) extending between the divider plate and the chilling duct inner wall and arranged to define a downwards flow in a downward flow section from the chilling inlet to a chilling siphon space and an upwards flow in an upward flow section from the chilling siphon space to the chilling outlet.
Use of a hydrogel which contains polysaccharides or their salts containing α-L-guluronic acid (GuIUA) and β-D-mannuronic acid (ManUA), wherein the carbohydrate units of the polysaccharides are not covalently crosslinked via chemical linkers, for the in vitro culture of cells and/or tissues of the nervous system, characterized in that the hydrogel comprises a divalent or multivalent cation content of 1 mmol/L to 4 mmol/L.
A current sensor comprising: a conductor through which a current to be measured flows; a first magnetoelectric conversion element disposed near the conductor; a second magnetoelectric conversion element disposed on the opposite side of the first magnetoelectric conversion element across the conductor; an isolating member; and a metal plate isolated from the conductor, and wherein: a part of the conductor has a level difference, and the conductor is disposed so as not to contact with the isolating member by the level difference, and further comprising a mold member for molding the conductor, the first magnetoelectric conversion element, the second magnetoelectric conversion element, the isolating member and the metal plate, characterized in that the isolating member supports the first and second magnetoelectric conversion elements (213a, 213b), wherein: the isolating member is not supported by the conductor, but is supported by the metal plate, and wherein: the metal plate is in contact with the isolating member, and a part of the metal plate is exposed from the mold member. a conductor through which a current to be measured flows; a first magnetoelectric conversion element disposed near the conductor; a second magnetoelectric conversion element disposed on the opposite side of the first magnetoelectric conversion element across the conductor; an isolating member; and a metal plate isolated from the conductor, and wherein: a part of the conductor has a level difference, and the conductor is disposed so as not to contact with the isolating member by the level difference, and further comprising a mold member for molding the conductor, the first magnetoelectric conversion element, the second magnetoelectric conversion element, the isolating member and the metal plate, a part of the conductor has a level difference, and the conductor is disposed so as not to contact with the isolating member by the level difference, and further comprising a mold member for molding the conductor, the first magnetoelectric conversion element, the second magnetoelectric conversion element, the isolating member and the metal plate, characterized in that the isolating member supports the first and second magnetoelectric conversion elements (213a, 213b), wherein: the isolating member is not supported by the conductor, but is supported by the metal plate, and wherein: the metal plate is in contact with the isolating member, and a part of the metal plate is exposed from the mold member. the isolating member is not supported by the conductor, but is supported by the metal plate, and wherein: the metal plate is in contact with the isolating member, and a part of the metal plate is exposed from the mold member.
A surface roughening apparatus for roughening a surface of a metal stock, the surface roughening apparatus comprising: a first mold having a plurality of first protrusions each formed in an angular shape, wherein the plurality of first protrusions is formed on a surface of the first mold; characterised by a second mold having a plurality of second protrusions each formed in an angular shape, wherein the plurality of second protrusions is formed on a surface of the second mold, wherein a height of each of the first protrusions is greater than a height of each of the second protrusions, a tip angle of each of the first protrusions is smaller than a tip angle of each of the second protrusions, the surface roughening apparatus is configured to press the first mold in the metal stock in a state where the surface of the first mold faces a first surface of the metal stock such that recesses are formed by the plurality of first protrusions, each recess having a shape corresponding to a shape of each of the first protrusions in the metal stock, and the surface roughening apparatus is configured to respectively press the plurality of second protrusions into the recesses formed by the plurality of first protrusions such that each of the recesses formed by the plurality of first protrusions in the metal stock is deformed into an undercut shape. a first mold having a plurality of first protrusions each formed in an angular shape, wherein the plurality of first protrusions is formed on a surface of the first mold; characterised by a second mold having a plurality of second protrusions each formed in an angular shape, wherein the plurality of second protrusions is formed on a surface of the second mold, wherein a height of each of the first protrusions is greater than a height of each of the second protrusions, a tip angle of each of the first protrusions is smaller than a tip angle of each of the second protrusions, the surface roughening apparatus is configured to press the first mold in the metal stock in a state where the surface of the first mold faces a first surface of the metal stock such that recesses are formed by the plurality of first protrusions, each recess having a shape corresponding to a shape of each of the first protrusions in the metal stock, and the surface roughening apparatus is configured to respectively press the plurality of second protrusions into the recesses formed by the plurality of first protrusions such that each of the recesses formed by the plurality of first protrusions in the metal stock is deformed into an undercut shape.
A method for use in an authentication server to obtain access to a secure server for a client that has issued a request for access to the secure server, without further intervention by the user of the client, the method comprising: the authentication server receiving an authentication challenge sent by the secure server to the client, the authentication challenge including the identity of the secure server, the Internet Protocol address of the client, a random number, and the identity of the authentication server, wherein the authentication server is trusted by the secure server; and the authentication server generating a ticket having a digital signature applied using a private key of the authentication server, wherein the ticket includes at least part of the authentication challenge sent by the secure server; and wherein the secure server, upon receiving the ticket: verifies the digital signature using a public key corresponding to the private key of the authentication server; verifies the part of the authentication challenge included in the ticket; and grants access to the client. the authentication server receiving an authentication challenge sent by the secure server to the client, the authentication challenge including the identity of the secure server, the Internet Protocol address of the client, a random number, and the identity of the authentication server, wherein the authentication server is trusted by the secure server; and the authentication server generating a ticket having a digital signature applied using a private key of the authentication server, wherein the ticket includes at least part of the authentication challenge sent by the secure server; and wherein the secure server, upon receiving the ticket: verifies the digital signature using a public key corresponding to the private key of the authentication server; verifies the part of the authentication challenge included in the ticket; and grants access to the client. verifies the digital signature using a public key corresponding to the private key of the authentication server; verifies the part of the authentication challenge included in the ticket; and grants access to the client.
Method for interchanging data between two devices (8, 8a, 8b) of a network, which makes use of a communication protocol with an interface in accordance with the OPC-UA standard for interchanging data, wherein the communication protocol comprises an interface in accordance with the Stream Reservation Protocol standard or Multiple Stream Registration Protocol (MSRP) standard according to IEEE 802.1Qat, so the data is able to be interchanged between the two devices (8, 8a, 8b) via both interfaces (13, 18) in a prescribed period of time.
A method for producing a block copolymer, which comprises: subjecting a mixture of styrene or a derivative thereof and α-methylstyrene to living anionic polymerization in the presence of a polymerization initiator by means of a microreactor having a channel being capable of mixing a plurality of liquids with each other, to thereby obtain an intermediate polymer having a polymer unit derived from α-methylstyrene bonded to one end of a polymer block derived from styrene or the derivative thereof, and then subjecting a (meth)acrylate compound (c) to living anionic polymerization in the presence of a polymerization initiator so that the polymer unit derived from α-methylstyrene in the intermediate polymer serves as a propagation end, to thereby form a polymer block derived from the (meth)acrylate compound (c). subjecting a mixture of styrene or a derivative thereof and α-methylstyrene to living anionic polymerization in the presence of a polymerization initiator by means of a microreactor having a channel being capable of mixing a plurality of liquids with each other, to thereby obtain an intermediate polymer having a polymer unit derived from α-methylstyrene bonded to one end of a polymer block derived from styrene or the derivative thereof, and then subjecting a (meth)acrylate compound (c) to living anionic polymerization in the presence of a polymerization initiator so that the polymer unit derived from α-methylstyrene in the intermediate polymer serves as a propagation end, to thereby form a polymer block derived from the (meth)acrylate compound (c).
A method for determining a transmittance of electromagnetic radiation through a contact lens in direct contact with an ocular surface, comprising: measuring a first intensity of radiation reflected by at least a portion of an ocular surface with an intensity measuring device; positioning a contact lens covering and in direct contact with at least a portion of the ocular surface; measuring a second intensity of radiation transmitted through the contact lens that is reflected by at least one region of the ocular surface that is covered by the contact lens with the intensity measuring device; and calculating a transmittance of electromagnetic radiation through the contact lens using the measurements of the first intensity and the second intensity. measuring a first intensity of radiation reflected by at least a portion of an ocular surface with an intensity measuring device; positioning a contact lens covering and in direct contact with at least a portion of the ocular surface; measuring a second intensity of radiation transmitted through the contact lens that is reflected by at least one region of the ocular surface that is covered by the contact lens with the intensity measuring device; and calculating a transmittance of electromagnetic radiation through the contact lens using the measurements of the first intensity and the second intensity.