mhurhangee/ep-ind-claims huggingface dataset:
A pharmaceutical kit for use in a method of treatment of a human patient suffering from non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC), malignant glioma, breast cancer, esophageal cancer, gastric cancer, renal cancer, cervical cancer, prostate cancer, ovarian cancer, pancreatic cancer, hepatocellular cancer or colorectal cancer, including metastatic forms thereof, comprising a first compartment which comprises an effective amount of a Human Epidermal Growth Factor Receptor (Human EGFR) targeted monoclonal antibody (mAB) selected from the group consisting of cetuximab, panitumumab, zalutumumab, nimotuzumab, matuzumab and necitumumab, and a second compartment which comprises an effective amount of the irreversible tyrosine kinase inhibitor BIBW 2992 or a pharmaceutically acceptable salt thereof.
An early strengthening agent for a hydraulic composition, comprising one or more compounds selected from the group consisting of: a compound represented by the following general formula: wherein A 1 represents an alkylene group having 2 to 4 carbon atoms, m1, m2 and m3 each represent an integer indicating the number of moles of A 1 O added and the average of the sum in total of m1, m2 and m3 in the compound represented by the general formula is 0.5 to 2.5.
A wheel comprising a spoke formed with a mounting hole that extends in a radial direction of said wheel, wherein said spoke further comprises a first through hole that extends in an axial direction perpendicular to the radial direction and that is in spatial communication with said mounting hole; the wheel further comprising a a rim connected to said spoke and formed with a second through hole that extends in the radial direction and that is aligned with said mounting hole; and a connecting unit connecting said spoke with said rim and including a rod extending through said second through hole into said mounting hole, and being formed with an engaging hole that extends in the axial direction and that is aligned with said first through hole, and a fastener extending through said first through hole into said engaging hole and engaging with said engaging hole. wherein said spoke further comprises a first through hole that extends in an axial direction perpendicular to the radial direction and that is in spatial communication with said mounting hole; the wheel further comprising a a rim connected to said spoke and formed with a second through hole that extends in the radial direction and that is aligned with said mounting hole; and a connecting unit connecting said spoke with said rim and including a rod extending through said second through hole into said mounting hole, and being formed with an engaging hole that extends in the axial direction and that is aligned with said first through hole, and a fastener extending through said first through hole into said engaging hole and engaging with said engaging hole. a rod extending through said second through hole into said mounting hole, and being formed with an engaging hole that extends in the axial direction and that is aligned with said first through hole, and a fastener extending through said first through hole into said engaging hole and engaging with said engaging hole.
A porous membrane comprising an aromatic hydrophobic polymer and a block copolymer of the formula: A-B-A or A-B, wherein block A is: a copolymer of glycidol and allyl glycidyl ether, wherein one or more of the allyl groups of the copolymer have been replaced with a group of the formula: -(CH 2) a -S-(CH 2) b -X, wherein a is 3 and b is 1 to 3, and X is selected from an acidic group, a basic group, a cation, an anion, a zwitterion, a group of the formula -C (COOH)(NH 2), and a group of the formula - C (COOH)(NHAc), or a salt thereof; and block B is an aromatic hydrophobic polymeric segment selected from polysulfone, polyethersulfone, polyphenylene ether, polyphenylene oxide, polycarbonate, poly(phthalazinone ether sulfone ketone), polyether ketone, polyether ether ketone, polyether ketone ketone, polyimide, polyetherimide, and polyamide-imide. a copolymer of glycidol and allyl glycidyl ether, wherein one or more of the allyl groups of the copolymer have been replaced with a group of the formula: -(CH 2) a -S-(CH 2) b -X, wherein a is 3 and b is 1 to 3, and X is selected from an acidic group, a basic group, a cation, an anion, a zwitterion, a group of the formula -C (COOH)(NH 2), and a group of the formula - C (COOH)(NHAc), or a salt thereof; and block B is an aromatic hydrophobic polymeric segment selected from polysulfone, polyethersulfone, polyphenylene ether, polyphenylene oxide, polycarbonate, poly(phthalazinone ether sulfone ketone), polyether ketone, polyether ether ketone, polyether ketone ketone, polyimide, polyetherimide, and polyamide-imide.
A noise reduction system for actively compensating background noise in a passenger transport area of a vehicle, comprising a control unit, at least one microphone for detecting a background noise, at least one sound generator for generating antinoise and a position detection unit for detecting a position and/or orientation of the head of a user in the passenger transport area, wherein the control unit - is coupled to the microphone on the input side and is configured to receive a background noise signal, - is coupled to the position detection unit on the input side, is configured to receive position data and to determine a position signal from the position data, the position signal indicating the position and/or orientation of the head of the user relative to the position detection unit, - is configured to generate an antinoise signal from the background noise signal and the position signal, - is coupled to the sound generator on the output side and is configured to provide the antinoise signal, wherein the sound generator is configured to generate antinoise from the antinoise signal such that, by superposition of the antinoise in a quiet zone (20a, 20b) within the passenger transport area, which antinoise in phase opposition with the background noise, active reduction of the background noise can be achieved, wherein the position detection unit is a 3D camera arrangement and the camera arrangement comprises at least one first and one second camera (18a, 18b), characterized in that the 3D camera arrangement forms a spatially enclosed structural unit together with the at least one microphone, the at least one sound generator and the control unit, wherein a stereo base between the first and the second camera (18a, 18b) is projecting downwards. - is coupled to the microphone on the input side and is configured to receive a background noise signal, - is coupled to the position detection unit on the input side, is configured to receive position data and to determine a position signal from the position data, the position signal indicating the position and/or orientation of the head of the user relative to the position detection unit, - is configured to generate an antinoise signal from the background noise signal and the position signal, - is coupled to the sound generator on the output side and is configured to provide the antinoise signal,
A mobile wireless communications system comprising: a mobile wireless communications device comprising a portable housing, a wireless transceiver carried by said portable housing, a processor carried by said portable housing and coupled to said wireless transceiver, and a near-field communication, NFC, device coupled to said processor; an adjacent NFC device configured to communicate directly with said mobile wireless communications device and comprising a plurality of pairs of discontinuous NFC circuit segments, and a respective switch assembly configured to selectively couple each pair of discontinuous NFC circuit segments to establish NFC communication with said NFC device. a mobile wireless communications device comprising a portable housing, a wireless transceiver carried by said portable housing, a processor carried by said portable housing and coupled to said wireless transceiver, and a near-field communication, NFC, device coupled to said processor; a portable housing, a wireless transceiver carried by said portable housing, a processor carried by said portable housing and coupled to said wireless transceiver, and a near-field communication, NFC, device coupled to said processor; an adjacent NFC device configured to communicate directly with said mobile wireless communications device and comprising a plurality of pairs of discontinuous NFC circuit segments, and a respective switch assembly configured to selectively couple each pair of discontinuous NFC circuit segments to establish NFC communication with said NFC device. a plurality of pairs of discontinuous NFC circuit segments, and a respective switch assembly configured to selectively couple each pair of discontinuous NFC circuit segments to establish NFC communication with said NFC device.
Driving assistance method for a vehicle, comprising the following steps: obtaining road information regarding a road the vehicle is driving on; automatically detecting uneven surface regions of the road using the obtained road information; and adapting at least one driving function of the vehicle depending on the detection of an uneven surface region of the road; characterized in that the road information is obtained using sensor data of the vehicle, the sensor data comprising at least one of camera sensor data, radar sensor data, lidar sensor data and infrared sensor data, wherein a periodic undulation of the uneven surface region of the road in a direction perpendicular to the road is determined using the road information, and wherein the driving function of the vehicle is adapted depending on the determined periodic undulation. obtaining road information regarding a road the vehicle is driving on; automatically detecting uneven surface regions of the road using the obtained road information; and adapting at least one driving function of the vehicle depending on the detection of an uneven surface region of the road; characterized in that the road information is obtained using sensor data of the vehicle, the sensor data comprising at least one of camera sensor data, radar sensor data, lidar sensor data and infrared sensor data, wherein a periodic undulation of the uneven surface region of the road in a direction perpendicular to the road is determined using the road information, and wherein the driving function of the vehicle is adapted depending on the determined periodic undulation.
An IC tag issuing apparatus for writing identification data to IC tags and issuing the result, the IC tags arranged in multiple rows aligned on an IC tag continuous body, the IC tag issuing apparatus comprising: a plurality of writing row antenna units arranged to face each row of the IC tags arranged in multiple rows, respectively, for writing the identification data to the IC tags by an electromagnetic induction method; an electric-wave antenna unit arranged at a downstream side in a conveyance direction of the IC tag continuous body from the plurality of writing row antenna units for writing the identification data to the IC tags by an electric wave method, wherein the communication region of the electric-wave antenna unit using the electric wave method is wider than that of the electromagnetic induction method; and a writing control unit for determining whether or not the identification data could be successfully written to each of the IC tags by the plurality of writing row antenna units, wherein the electric-wave antenna unit is adapted to write the identification data to the IC tags for which it is determined by the writing control unit that the identification data could not be written by the plurality of writing row antenna units. a plurality of writing row antenna units arranged to face each row of the IC tags arranged in multiple rows, respectively, for writing the identification data to the IC tags by an electromagnetic induction method; an electric-wave antenna unit arranged at a downstream side in a conveyance direction of the IC tag continuous body from the plurality of writing row antenna units for writing the identification data to the IC tags by an electric wave method, wherein the communication region of the electric-wave antenna unit using the electric wave method is wider than that of the electromagnetic induction method; and a writing control unit for determining whether or not the identification data could be successfully written to each of the IC tags by the plurality of writing row antenna units, wherein the electric-wave antenna unit is adapted to write the identification data to the IC tags for which it is determined by the writing control unit that the identification data could not be written by the plurality of writing row antenna units.
A condition monitoring system comprising: a system comprising a rotating body that rotates around a rotation axis with a direction of the rotation axis not being vertical and an apparatus for measuring vibration of the rotating body, the apparatus comprising: a vibration detector fixed to the rotating body, the vibration detector wirelessly outputting vibration data detected by sensing an acceleration; and a control device that is configured to obtain at least one of rotation phase information and a rotation speed of the rotating body based on a variation component in the vibration data varied with a rotation period of the rotating body as the vibration detector is affected by gravity, characterized in that the rotating body is a rotating ring of a bearing that supports a rotation shaft of a rotating structure, wherein the control device is configured to detect rotation phase information and a rotation speed of the rotating body obtained by the control device by using the variation component in vibration data detected by the vibration detector, the condition monitoring system further comprises a high-pass filter that is configured to remove the variation component from the vibration data; and a monitoring apparatus that is configured to monitor a condition of the rotating body by subjecting the vibration data to frequency analysis by using an output signal from the high-pass filter and using a result of the frequency analysis and the detected rotation speed and rotation phase information. a vibration detector fixed to the rotating body, the vibration detector wirelessly outputting vibration data detected by sensing an acceleration; and a control device that is configured to obtain at least one of rotation phase information and a rotation speed of the rotating body based on a variation component in the vibration data varied with a rotation period of the rotating body as the vibration detector is affected by gravity, characterized in that the rotating body is a rotating ring of a bearing that supports a rotation shaft of a rotating structure, wherein the control device is configured to detect rotation phase information and a rotation speed of the rotating body obtained by the control device by using the variation component in vibration data detected by the vibration detector, the condition monitoring system further comprises a high-pass filter that is configured to remove the variation component from the vibration data; and a monitoring apparatus that is configured to monitor a condition of the rotating body by subjecting the vibration data to frequency analysis by using an output signal from the high-pass filter and using a result of the frequency analysis and the detected rotation speed and rotation phase information.
Terminal row for a terminal apparatus which can be attached to an electronics housing in an insertion direction and can be connected to an electronics component which is intended to be received in the electronics housing, wherein a predetermined number of electrical individual conductors or plugs can be connected to the terminal row in order to establish a connection between the electrical individual conductors or plugs and the electronics component, wherein the at least one terminal row is composed of a plurality of main housings (20, 20A-20F), at least two main housings (20, 20A-20F) of which differ, wherein the main housings (20, 20A-20F) are present in a manner separated from one another in a preassembly state and can be attached to one another along a lining-up direction for forming the terminal row, wherein the main housings (20, 20A-20F) each have a length which is measured in the lining-up direction and corresponds to a predetermined pitch dimension or to an integer multiple of the predetermined pitch dimension, characterized in that the main housings (20, 20A-20F) each have a first side wall which extends transversely to the lining-up direction and a second side wall which is parallel to the first side wall, wherein adjacent main housings (20, 20A-20F) are attached to one another in such a way that the first side wall of a main housing (20-20A-20F) bears against the second side wall of an adjacent main housing (20-20A-20F), and adjacent main housings (20, 02A-20F) are connected to one another in an interlocking, force-fitting or cohesive manner in an assembly state, in which the main housings (20, 20A-20F) are attached to one another, via the side walls (215, 216) which bear against one another.
An electrical connector comprising: a terminal having at least one tab (30, 32) that protrudes from a side of the terminal; and a connector body having a cavity that is constructed to receive the terminal, having at least one rail (50, 52) that protrudes into the cavity, and having at least one knob (54, 56) that protrudes into the cavity at a position that is adjacent the at least one rail (50, 52), wherein, when the terminal is received in the cavity in its final position, the at least one tab (30, 32) bears against the at least one rail (50, 52), and the at least one tab (30, 32) bears against the at least one knob (54, 56) to prevent the terminal from being moved in a forward axial direction within the cavity; characterized in that the terminal has a recess (26, 27) and the connector body has a ramp protruding into the cavity, wherein, when the terminal is received in the cavity in its final position, the ramp mates with the recess (26, 27) which, in combination with the tab (30, 32) bearing against the rail (50, 52), prevents the terminal from being moved in a rearward axial direction within the cavity. a terminal having at least one tab (30, 32) that protrudes from a side of the terminal; and a connector body having a cavity that is constructed to receive the terminal, having at least one rail (50, 52) that protrudes into the cavity, and having at least one knob (54, 56) that protrudes into the cavity at a position that is adjacent the at least one rail (50, 52), wherein, when the terminal is received in the cavity in its final position, the at least one tab (30, 32) bears against the at least one rail (50, 52), and the at least one tab (30, 32) bears against the at least one knob (54, 56) to prevent the terminal from being moved in a forward axial direction within the cavity; characterized in that the terminal has a recess (26, 27) and the connector body has a ramp protruding into the cavity, wherein, when the terminal is received in the cavity in its final position, the ramp mates with the recess (26, 27) which, in combination with the tab (30, 32) bearing against the rail (50, 52), prevents the terminal from being moved in a rearward axial direction within the cavity.
A method for preparing an enantiomerically enriched form of 2-[2-(2-chlorothiazol-5-yl)-2-hydroxy-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one of the formula: where the asterisk * shows the stereogenic center; or of a tautomer thereof; which method comprises reducing 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one of the formula 1 or a tautomer thereof with a reduction agent selected from the group consisting of formic acid HC(=O)OH, formates of the formula HC(=O)O-M + and mixtures of formic acid HC(=O)OH and one or more formates of the formula HC(=O)OM +, where M + is a cation equivalent; in the presence of a chiral transition metal catalyst and optionally of a base, where in case that formic acid is used as reduction agent, the reaction is carried out in the presence of a base; to obtain an enantiomerically enriched form of the pyrimidinone of the formula or of a tautomer thereof. where the asterisk * shows the stereogenic center; or of a tautomer thereof; which method comprises reducing 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one of the formula 1 or a tautomer thereof with a reduction agent selected from the group consisting of formic acid HC(=O)OH, formates of the formula HC(=O)O-M + and mixtures of formic acid HC(=O)OH and one or more formates of the formula HC(=O)OM +, where M + is a cation equivalent; in the presence of a chiral transition metal catalyst and optionally of a base, where in case that formic acid is used as reduction agent, the reaction is carried out in the presence of a base; to obtain an enantiomerically enriched form of the pyrimidinone of the formula or of a tautomer thereof.
A process for manufacturing lyocell filament yarn with improved mechanical properties, the process comprising: a. preparing a homogenous solution of cellulose in concentrated NMMO solution to obtain cellulose dope, and storing said cellulose dope in a lyocell dope vessel, b. pumping stored cellulose dope via a metering pump into a spin pack containing a spinneret that extrudes the cellulose dope as spun filaments; c. stretching extruded spun filament yarn using a winder while passing filaments through an air-gap at controlled conditions and in a regeneration bath containing a solution for partial regeneration of the extruded spun filament yarn; d. guiding the partially regenerated filament yarn to filament guiding drum, which passes said filament yarn to a main drum spinning at a speed less than the winder speed, said main drum having a filament yarn washing section and a filament yarn drying section, wherein the filament yarn is fully regenerated in the filament yarn washing section by passing it through sequential washing zones, each successive washing zone containing a washing solution of successively decreasing concentration of NMMO, said concentration successively decreasing up to 0 % by weight of NMMO in filament, maintained by circulating system, and e. drying the washed filament yarn on the filament yarn drying section at a temperature selected from the range of 40 °C to less than 100 °C. a. preparing a homogenous solution of cellulose in concentrated NMMO solution to obtain cellulose dope, and storing said cellulose dope in a lyocell dope vessel, b. pumping stored cellulose dope via a metering pump into a spin pack containing a spinneret that extrudes the cellulose dope as spun filaments; c. stretching extruded spun filament yarn using a winder while passing filaments through an air-gap at controlled conditions and in a regeneration bath containing a solution for partial regeneration of the extruded spun filament yarn; d. guiding the partially regenerated filament yarn to filament guiding drum, which passes said filament yarn to a main drum spinning at a speed less than the winder speed, said main drum having a filament yarn washing section and a filament yarn drying section, wherein the filament yarn is fully regenerated in the filament yarn washing section by passing it through sequential washing zones, each successive washing zone containing a washing solution of successively decreasing concentration of NMMO, said concentration successively decreasing up to 0 % by weight of NMMO in filament, maintained by circulating system, and e. drying the washed filament yarn on the filament yarn drying section at a temperature selected from the range of 40 °C to less than 100 °C.