A staple cartridge assembly, comprising: a cartridge body, comprising: a deck configured to support the tissue of a patient; a longitudinal slot defined in the deck, wherein the longitudinal slot is configured to receive a cutting member, and wherein the deck comprises a first deck portion on a first side of the longitudinal slot and a second deck portion on a second side of the longitudinal slot; a first row of staple cavities defined in the first deck portion adjacent the longitudinal slot, and wherein a first distance is defined between the first row of staple cavities and the longitudinal slot; and a second row of staple cavities defined in the second deck portion adjacent the longitudinal slot, and wherein a second distance is defined between the second row of staple cavities and the longitudinal slot, and wherein the second distance is different than the first distance; staples removably stored in the first row of staple cavities and the second row of staple cavities; and a sled, wherein the sled comprises: a first longitudinal ramp configured to eject the staples from the first row of staple cavities; and a second longitudinal ramp configured to eject the staples from the second row of staple cavities; wherein the first distance is defined between the first longitudinal ramp and the longitudinal slot, and wherein the second distance is defined between second longitudinal ramp and the longitudinal slot; wherein each staple comprises: a crown; and a tissue clenching portion (244p, 244d); characterised in that: each staple further comprises: a cam portion integrally formed with the crown, wherein the respective longitudinal ramp (355a, 355a') of the sled is configured to directly engage the cam portion; and the tissue clenching portion (244p, 244d) being offset from the cam portion; wherein the cam portions of the staples in the first row of staple cavities are positioned closer to the longitudinal slot than the tissue clenching portions (244p, 244d); and the tissue clenching portions (244p, 244d) of the staples in the second row of staple cavities are positioned closer to the longitudinal slot than the cam portions; wherein the first distance is shorter than the second distance. a cartridge body, comprising: a deck configured to support the tissue of a patient; a longitudinal slot defined in the deck, wherein the longitudinal slot is configured to receive a cutting member, and wherein the deck comprises a first deck portion on a first side of the longitudinal slot and a second deck portion on a second side of the longitudinal slot; a first row of staple cavities defined in the first deck portion adjacent the longitudinal slot, and wherein a first distance is defined between the first row of staple cavities and the longitudinal slot; and a second row of staple cavities defined in the second deck portion adjacent the longitudinal slot, and wherein a second distance is defined between the second row of staple cavities and the longitudinal slot, and wherein the second distance is different than the first distance; a deck configured to support the tissue of a patient; a longitudinal slot defined in the deck, wherein the longitudinal slot is configured to receive a cutting member, and wherein the deck comprises a first deck portion on a first side of the longitudinal slot and a second deck portion on a second side of the longitudinal slot; a first row of staple cavities defined in the first deck portion adjacent the longitudinal slot, and wherein a first distance is defined between the first row of staple cavities and the longitudinal slot; and a second row of staple cavities defined in the second deck portion adjacent the longitudinal slot, and wherein a second distance is defined between the second row of staple cavities and the longitudinal slot, and wherein the second distance is different than the first distance; staples removably stored in the first row of staple cavities and the second row of staple cavities; and a sled, wherein the sled comprises: a first longitudinal ramp configured to eject the staples from the first row of staple cavities; and a second longitudinal ramp configured to eject the staples from the second row of staple cavities; a first longitudinal ramp configured to eject the staples from the first row of staple cavities; and a second longitudinal ramp configured to eject the staples from the second row of staple cavities; wherein the first distance is defined between the first longitudinal ramp and the longitudinal slot, and wherein the second distance is defined between second longitudinal ramp and the longitudinal slot; wherein each staple comprises: a crown; and a tissue clenching portion (244p, 244d); a crown; and a tissue clenching portion (244p, 244d); each staple further comprises: a cam portion integrally formed with the crown, wherein the respective longitudinal ramp (355a, 355a') of the sled is configured to directly engage the cam portion; and the tissue clenching portion (244p, 244d) being offset from the cam portion; a cam portion integrally formed with the crown, wherein the respective longitudinal ramp (355a, 355a') of the sled is configured to directly engage the cam portion; and the tissue clenching portion (244p, 244d) being offset from the cam portion; wherein the cam portions of the staples in the first row of staple cavities are positioned closer to the longitudinal slot than the tissue clenching portions (244p, 244d); and the tissue clenching portions (244p, 244d) of the staples in the second row of staple cavities are positioned closer to the longitudinal slot than the cam portions; wherein the first distance is shorter than the second distance.