Composition comprising at least one 7β-hydroxycholesterol derivative and a lipid vehicle, wherein said lipid vehicle comprises an oil or a mixture of oils, excluding a lipid vehicle consisting of lipid vesicles formed from one or more lipid layer(s) or consisting of phospholipids in the non-liposomal form, in which the 7β-hydroxycholesterol derivative corresponds to formula in which: - A represents a -C R 1 group in which R 1 is a saturated heterocycle comprising 5 to 14 members and including 1 or 2 heteroatoms, unsubstituted or substituted with at least one linear or branched C 1 -C 6 alkyl or a group selected from OR, NRR', NHR and SR, where R and R', independently, represent hydrogen, a linear or branched C 1 -C 12, preferably C 1 -C 6, alkyl, or an unsubstituted aryl; or a -(R 2) n - group in which R 2 is an amino acid residue bound by its C-terminal end and n= 1 to 3, each of the R 2 being identical or different, in which the N-terminal end of said amino acid may be substituted with a -C R 3 group in which R 3 is a mono- or polycyclic C 6 -C 14 arylalkyl group; a mono- or polycyclic C 5 -C 14 heteroarylalkyl group that may comprise one or more heteroatoms, which may be identical or different; a mono- or polycyclic C 6 -C 14 arylalkyloxy group or a mono- or polycyclic C 5 -C 14 heteroarylalkyloxy group that may comprise one or more heteroatoms, which may be identical or different, - B represents a -C R 4 group, in which R 4 is a linear or branched C 1 -C 12, preferably C 1 -C 6, alkyl, unsubstituted or substituted with a group selected from OR, NRR', NHR and SR, as defined above; an aryl group, unsubstituted or substituted with a group selected from OR, NRR', NHR and SR, as defined above; or R 4 represents OR 5, in which R 5 is a linear or branched C 1 -C 12, preferably C 1 -C 6, alkyl. - A represents a -C R 1 group in which R 1 is a saturated heterocycle comprising 5 to 14 members and including 1 or 2 heteroatoms, unsubstituted or substituted with at least one linear or branched C 1 -C 6 alkyl or a group selected from OR, NRR', NHR and SR, where R and R', independently, represent hydrogen, a linear or branched C 1 -C 12, preferably C 1 -C 6, alkyl, or an unsubstituted aryl; or a -(R 2) n - group in which R 2 is an amino acid residue bound by its C-terminal end and n= 1 to 3, each of the R 2 being identical or different, in which the N-terminal end of said amino acid may be substituted with a -C R 3 group in which R 3 is a mono- or polycyclic C 6 -C 14 arylalkyl group; a mono- or polycyclic C 5 -C 14 heteroarylalkyl group that may comprise one or more heteroatoms, which may be identical or different; a mono- or polycyclic C 6 -C 14 arylalkyloxy group or a mono- or polycyclic C 5 -C 14 heteroarylalkyloxy group that may comprise one or more heteroatoms, which may be identical or different, a -C R 1 group in which R 1 is a saturated heterocycle comprising 5 to 14 members and including 1 or 2 heteroatoms, unsubstituted or substituted with at least one linear or branched C 1 -C 6 alkyl or a group selected from OR, NRR', NHR and SR, where R and R', independently, represent hydrogen, a linear or branched C 1 -C 12, preferably C 1 -C 6, alkyl, or an unsubstituted aryl; or a -(R 2) n - group in which R 2 is an amino acid residue bound by its C-terminal end and n= 1 to 3, each of the R 2 being identical or different, in which the N-terminal end of said amino acid may be substituted with a -C R 3 group in which R 3 is a mono- or polycyclic C 6 -C 14 arylalkyl group; a mono- or polycyclic C 5 -C 14 heteroarylalkyl group that may comprise one or more heteroatoms, which may be identical or different; a mono- or polycyclic C 6 -C 14 arylalkyloxy group or a mono- or polycyclic C 5 -C 14 heteroarylalkyloxy group that may comprise one or more heteroatoms, which may be identical or different, - B represents a -C R 4 group, in which R 4 is a linear or branched C 1 -C 12, preferably C 1 -C 6, alkyl, unsubstituted or substituted with a group selected from OR, NRR', NHR and SR, as defined above; an aryl group, unsubstituted or substituted with a group selected from OR, NRR', NHR and SR, as defined above; or R 4 represents OR 5, in which R 5 is a linear or branched C 1 -C 12, preferably C 1 -C 6, alkyl.