A method of processing uniform mailpieces or "runs", in which, in a mail preparation zone, the mailpieces of a "run" are prepared in trays or on trolleys, and the prepared mailpieces are brought to the inlet of a postal sorting machine for a first sorting pass, and in which the mailpieces are fed in series into the sorting machine comprising a sorting conveyor and sorting outlets, a digital image of each mailpiece is formed in the sorting machine, and processing is applied to each digital image for automatically recognizing address information for the purpose of automatically directing the corresponding mailpiece through the sorting conveyor towards a determined sorting outlet of the sorting machine, and in which a digital model of the run is built in a database, the digital run model being defined by data characterizing the graphical appearance of the mailpieces of the run and being associated in the database with setting indications usable by the automatic recognition processing, said method comprising the following steps in advance of the first pass of the mailpieces of the run through the sorting machine: a) using an interactive acquisition terminal that is located remote from the sorting machine to form a digital image of a certain mailpiece of the run, said interactive acquisition terminal comprising a scanner with a camera, a presentation stand on which an operator places said certain mailpiece of the run flat and facing the camera in order to input a digital image of the face of said mailpiece that bears a recipient address, and a man/machine interface with a display screen, with a keyboard and a pointer, which interface is connected to a data-processing unit connected to said database; b) in the data-processing unit and on the basis of this digital image, computing attributes or descriptors of the run so as to build (20, 21) said digital run model in said database; and c) in said database, associating said run model with said setting indications from said interactive acquisition terminal, said indications also being input from said interactive acquisition terminal and said indications comprising an indication of location in two dimensions of a region of interest in said digital image of said certain mailpiece which is being input with said pointer d) into said interactive acquisition terminal, introducing an indication corresponding to the contents of an address block to trigger an iterative information recognition process which operates in various different iterations different binarization algorithms and at the end of iterations, different binarization algorithms are determined which gave the result closed to the said information for designating this binarization algorithms as indication parameter. a) using an interactive acquisition terminal that is located remote from the sorting machine to form a digital image of a certain mailpiece of the run, said interactive acquisition terminal comprising a scanner with a camera, a presentation stand on which an operator places said certain mailpiece of the run flat and facing the camera in order to input a digital image of the face of said mailpiece that bears a recipient address, and a man/machine interface with a display screen, with a keyboard and a pointer, which interface is connected to a data-processing unit connected to said database; b) in the data-processing unit and on the basis of this digital image, computing attributes or descriptors of the run so as to build (20, 21) said digital run model in said database; and c) in said database, associating said run model with said setting indications from said interactive acquisition terminal, said indications also being input from said interactive acquisition terminal and said indications comprising an indication of location in two dimensions of a region of interest in said digital image of said certain mailpiece which is being input with said pointer d) into said interactive acquisition terminal, introducing an indication corresponding to the contents of an address block to trigger an iterative information recognition process which operates in various different iterations different binarization algorithms and at the end of iterations, different binarization algorithms are determined which gave the result closed to the said information for designating this binarization algorithms as indication parameter.