mhurhangee/ep-ind-claims huggingface dataset:
A method for preparing a DNA targeting agent suitable for the treatment of a cancer type, said method comprising identifying a cancer cell-specific DNA copy number variation resulting from an amplification of said cancer type, preferably by sequencing of a sample of said cancer type, and producing a sequence-specific DNA targeting agent comprising a nuclease capable of sequence-specific DNA cleavage of a non-coding region or a non-essential gene sequence comprised in said DNA copy number variation, preferably a patient-specific DNA targeting agent.
A liquid crystal display device, comprising: a liquid crystal panel; a backlight unit disposed at a rear side of the liquid crystal panel; a bottom cover in which the backlight unit is disposed; and a main support; wherein the backlight unit further comprises: an LED assembly; and a light guide plate having a first surface and a second surface opposite to the first surface, wherein the first surface faces the LED assembly; wherein the bottom cover further includes: a horizontal plane; and a side perpendicular to the horizontal plane, wherein the backlight unit is disposed over the horizontal plane, wherein the main support further includes: a side wall having a double structure of first (131 a) and second vertical portions; and a horizontal portion extending from from the first vertical portion, wherein the first vertical portion is configured to surround an outer surface of the side of the bottom cover, wherein the horizontal portion is configured to support the liquid crystal panel, wherein at least one elastic stopper is formed at the side wall of the second vertical portion of the main support and contacts the second surface of the light guide plate, wherein stoppers are formed at side walls disposed at both sides of and being perpendicular to the side wall of the main support including the elastic stopper to maintain an optical gap between the first surface (123 a) of the light guide plate and the LED assembly. a liquid crystal panel; a backlight unit disposed at a rear side of the liquid crystal panel; a bottom cover in which the backlight unit is disposed; and a main support; an LED assembly; and a light guide plate having a first surface and a second surface opposite to the first surface, wherein the first surface faces the LED assembly; a horizontal plane; and a side perpendicular to the horizontal plane, a side wall having a double structure of first (131 a) and second vertical portions; and a horizontal portion extending from from the first vertical portion,
A re-programmable non-volatile memory device comprising: a first memory cell-access line terminating at a first node; a second memory cell-access line terminating at a second node; a memory cell resistor of SiCr-based resistive material, connected to and between each of the first and second nodes for storing different reversibly settable resistance states respectively corresponding to different resistance values set by SiCr-facilitated migration, including electrical-field driven migration and/or electromigration where at least one element migrates along the resistor, in response to a current or voltage applied between the first and the second nodes. a first memory cell-access line terminating at a first node; a second memory cell-access line terminating at a second node; a memory cell resistor of SiCr-based resistive material, connected to and between each of the first and second nodes for storing different reversibly settable resistance states respectively corresponding to different resistance values set by SiCr-facilitated migration, including electrical-field driven migration and/or electromigration where at least one element migrates along the resistor, in response to a current or voltage applied between the first and the second nodes.
A method for enhancing transformation efficiency of a Bacillus licheniformis host cell comprising: (a) introducing into a parental Bacillus licheniformis host cell at least one copy of an exogenous nucleic acid construct comprising a promoter region operably linked to a polynucleotide encoding a ComS1 polypeptide, wherein the ComS1 polypeptide comprises an amino acid sequence comprising at least 90% sequence identity to SEQ ID NO: 2, and (b) isolating a daughter Bacillus licheniformis host cell comprising the polynucleotide encoding the ComS1 polypeptide. (a) introducing into a parental Bacillus licheniformis host cell at least one copy of an exogenous nucleic acid construct comprising a promoter region operably linked to a polynucleotide encoding a ComS1 polypeptide, wherein the ComS1 polypeptide comprises an amino acid sequence comprising at least 90% sequence identity to SEQ ID NO: 2, and (b) isolating a daughter Bacillus licheniformis host cell comprising the polynucleotide encoding the ComS1 polypeptide.
Battery comprising a wound electrode assembly including a first electrode plate, a second electrode plate and a separator therebetween, and defining a peripheral surface, characterized by a finishing member mounted on the peripheral surface and comprising a conducting portion contacting said first electrode plate and a non-conductive portion interposed between the conducting portion and the second electrode plate, wherein the first electrode plate and the second electrode plate are rolled and include each a roll end (110f, 120f), wherein the roll end of the first electrode plate contacts said conducting portion and wherein the non-conductive portion is interposed between the roll end of the second electrode plate and the conducting portion.
Method for implementing automatic railway traffic with an automatic train controller and train protection by means of data communication between a piece of on-board equipment of each train and a piece of trackside equipment, characterised in that when using a train moved by a locomotive with the transmission of a position signal, which indicates the front-side position of the locomotive of the train moved by a locomotive, a position signal prompts a front-side, deletable traffic restriction mark to be assigned to the locomotive by the trackside equipment, whereby the parts extending forward from the traffic restriction mark in each case of a track section which is travelled along by the train moved by a locomotive and is reported as occupied by the trackside equipment are treated as occupied and the traffic restriction mark is deleted, permitting a further travel of the train moved by a locomotive if, once the locomotive has arrived at the limit of the track section, the following track section is free.
A bistable electromagnetic actuator, in particular for a surgical instrument, comprising a stator arranged outside a tube, and a rotor that is mounted in the tube so as to be displaceable axially in the longitudinal direction, which is of a paramagnetic and/or ferromagnetic material, at least in part, and which can be reversibly moved between a first position and a second position by applying an electromagnetic field, wherein the rotor lies against a stop (44, 46) in the first and/or second position (6, 8), wherein the stator has two ring permanent magnets (12, 14) that are axially polarized in opposite directions, a coil for generating the electromagnetic field, and a magnetic return element having two stator pole shoes (20, 22), and the rotor does not project in an axial direction beyond the ring permanent magnets (12, 14) either in the first position or in the second position, wherein the magnetic return element with the stator pole shoes (20, 22) encloses the coil, and the stator pole shoes (20, 22) are arranged on both sides of the coil between the coil and the ring permanent magnets (12, 14), wherein the rotor has two rotor pole shoes (32, 34), characterized in that an axial width of the stator pole shoes (20, 22) is smaller than an axial width of the rotor pole shoes (32, 34).
A joystick device operable to control a vehicle, the joystick device having a movable steering member extending on an axis and adapted to be tilted from a neutral position in at least two directions including a forward and a backward direction, wherein the joystick device comprises a control unit, characterized in that: - the joystick device is provided with a forward gear engagement position defined between the neutral position and a maximum forward end position, - the movable steering member is configured to be self-centered to the forward gear engagement position after positioning the movable steering member at the forward gear engagement position, and - the control unit is adapted to generate control commands to increase and then maintain an increased forward speed of the vehicle if the movable steering member is moved from the forward gear engagement position towards the maximum forward end position, and wherein when the movable steering member springs back to the forward gear engagement position, the increased speed is maintained. - the joystick device is provided with a forward gear engagement position defined between the neutral position and a maximum forward end position, - the movable steering member is configured to be self-centered to the forward gear engagement position after positioning the movable steering member at the forward gear engagement position, and - the control unit is adapted to generate control commands to increase and then maintain an increased forward speed of the vehicle if the movable steering member is moved from the forward gear engagement position towards the maximum forward end position, and wherein when the movable steering member springs back to the forward gear engagement position, the increased speed is maintained.
A harvester (1, 50) comprising a belt drive (11, 30, 57) which has a drive pulley (13, 31, 57a) driven directly or indirectly by an internal combustion engine (10, 51) and at least one driven pulley (15, 32, 60), wherein a belt tensioning device (18, 35, 75, 76) is associated with the belt drive (11, 30, 57), characterised in that the harvester (1, 50) has a front harvesting attachment (2, 52) and a device arranged downstream of the front harvesting attachment in the direction of the flow of crop material and driven by way of the belt drive (11, 30, 57) for processing the crop material (5, 8, 54), and that a tensioning force produced in the belt drive (11, 30, 57) by the belt tensioning device (18, 35, 75, 76) is adjustable by means of an adjusting device (21, 37, 82) in dependence on the nature and state of the crop material, wherein the harvester (1, 50) has an input device (23, 66) which is connected to the adjusting device (21, 37, 82) and which is arranged in a driver's cab of the harvester (1, 50) and by way of which the nature or the state of the crop material can be manually input.
A method for decoding frames from multiple views, the method comprising: receiving a macroblock in a first frame taken from a first view to be decoded by a first decoder; decoding at least one macroblock in a corresponding second frame taken from a second view by a second decoder; decoding information regarding decoding synchronization frequency in terms of a number of macroblocks for controlling the decoders to synchronize between the first and the second view and a delay for decoding the macroblock in the first frame, the delay being defined in terms of a number of reconstructed macroblocks in the corresponding second frame; determining a group of macroblocks in the corresponding second frame taken from the second view usable as reference for inter-view prediction for the macroblock in the first frame, wherein said group of macroblocks is defined as a list of macroblocks (-1,j], where j is set to the decoding synchronization frequency multiplied by the delay, and added with a location of said macroblock minus 1; and when the number of macroblocks indicated by said delay have been reconstructed to a reference memory, starting the decoding of the macroblock in the first frame by the first decoder. receiving a macroblock in a first frame taken from a first view to be decoded by a first decoder; decoding at least one macroblock in a corresponding second frame taken from a second view by a second decoder; decoding information regarding decoding synchronization frequency in terms of a number of macroblocks for controlling the decoders to synchronize between the first and the second view and a delay for decoding the macroblock in the first frame, the delay being defined in terms of a number of reconstructed macroblocks in the corresponding second frame; determining a group of macroblocks in the corresponding second frame taken from the second view usable as reference for inter-view prediction for the macroblock in the first frame, wherein said group of macroblocks is defined as a list of macroblocks (-1,j], where j is set to the decoding synchronization frequency multiplied by the delay, and added with a location of said macroblock minus 1; and when the number of macroblocks indicated by said delay have been reconstructed to a reference memory, starting the decoding of the macroblock in the first frame by the first decoder.
An adaptor pallet comprising: - at least one load bearing deck to receive the wheels of a dolly, the load bearing decks being separated by at least one lifting point to receive the lifting forks of a forklift; and - at least one locking member to engage with the dolly; - activation means for manipulating the locking member, wherein the activation means comprises at least a lever and wherein said activation means is adapted to deactivate said locking member when rotated and adapted to activate said locking member when moved in a linear direction characterized in that - the lever is adapted to move an axle, to which locking members are attached, and in that - connected to said locking member is means for suspending said locking member in relation to its axle, wherein a dolly may be loaded albeit said locking member being activated. - at least one load bearing deck to receive the wheels of a dolly, the load bearing decks being separated by at least one lifting point to receive the lifting forks of a forklift; and - at least one locking member to engage with the dolly; - activation means for manipulating the locking member, wherein the activation means comprises at least a lever and wherein said activation means is adapted to deactivate said locking member when rotated and adapted to activate said locking member when moved in a linear direction characterized in that - the lever is adapted to move an axle, to which locking members are attached, and in that - connected to said locking member is means for suspending said locking member in relation to its axle, wherein a dolly may be loaded albeit said locking member being activated.
A catalyzed soot filter, comprising a wall flow substrate comprising an inlet end, an outlet end, a substrate axial length extending between the inlet end and the outlet end, and a plurality of passages defined by internal walls of the wall flow filter substrate; wherein the plurality of passages comprise inlet passages having an open inlet end and a closed outlet end, and outlet passages having a closed inlet end and an open outlet end; wherein a given inlet passage, an adjacent outlet passage, and the internal wall between said inlet and said outlet passage define an overall passage; wherein the internal walls of at least 20 % of the length of the overall passages are at least partially coated with a first and a second coating; wherein the internal wall of a given at least partially coated overall passage comprises the first coating that extends from the open inlet end to a first coating end, thereby defining a first coating length, wherein the first coating length is x % of the substrate axial length, with 20 ≤ x < 100; wherein said internal wall of said overall passage further comprises the second coating located downstream of the first coating, said second coating having a second coating length of y % of the substrate axial length, with 20 ≤ y < 100, wherein the second coating extends from the open outlet end to a second coating end, thereby defining the second coating length of y % of the substrate axial length; wherein the first and the second coating overlap in length by at least 20 % of the substrate axial length; wherein the first coating comprises an oxidation catalyst comprising platinum (Pt) and optionally palladium (Pd) and wherein the weight ratio of Pt:Pd in the first coating is in the range of from 1:0 to greater than 1:1; wherein the second coating comprises an oxidation catalyst comprising Pd and optionally Pt, wherein the Pt concentration in the second coating is lower than the Pt concentration in the first coating and wherein the weight ratio of Pt:Pd in the second coating is in the range of from 1:1 to 0:1; wherein the first coating and the second coating are present on the wall flow substrate at a coating loading ratio in the range of from 0.75 to 1.25, calculated as ratio of the loading of the first coating (in g/inch 3 (g/(2.54 cm) 3)): loading of the second coating (in g/inch 3 (g/(2.54 cm) 3)), wherein the loading of the first coating is in the range of from 0.05 to 1 g/inch 3 (g/(2.54 cm) 3), and wherein the loading of the second coating is in the range of from 0.05 to 1 g/inch 3 (g/(2.54 cm) 3).
A method of detecting a leak event within a wellbore, the method comprising: inducing a pressure differential within a wellbore comprising a fluid; obtaining a sample data set while inducing the pressure differential, wherein the sample data set is a sample of an acoustic signal originating within the wellbore, and wherein the sample data set is representative of the acoustic signal across a frequency spectrum; determining a plurality of frequency domain features of the sample data set, wherein each frequency domain feature of the plurality of frequency domain features is determined from across the frequency spectrum; determining a presence of a flow condition at one or more depths within the wellbore based on determining that the plurality of frequency domain features match a flow condition event signature; correlating the flow condition with the induced pressure differential; and determining a presence and location of a leak event within the wellbore based on the presence of the flow condition and the correlating of the flow condition with the induced pressure differential. inducing a pressure differential within a wellbore comprising a fluid; obtaining a sample data set while inducing the pressure differential, wherein the sample data set is a sample of an acoustic signal originating within the wellbore, and wherein the sample data set is representative of the acoustic signal across a frequency spectrum; determining a plurality of frequency domain features of the sample data set, wherein each frequency domain feature of the plurality of frequency domain features is determined from across the frequency spectrum; determining a presence of a flow condition at one or more depths within the wellbore based on determining that the plurality of frequency domain features match a flow condition event signature; correlating the flow condition with the induced pressure differential; and determining a presence and location of a leak event within the wellbore based on the presence of the flow condition and the correlating of the flow condition with the induced pressure differential.
Method for treating clothes in a dryer, particularly for removing wrinkles from clothes at the end of a clothes drying program or a clothes refreshing program, the dryer comprising a motor driving a fan and a drum, said fan driving a closed airflow through the rotating drum, the method comprising decreasing flow rate of airflow by reversing the rotation of the fan, characterised in that the airflow is passing through condensing means and heating means, in that, before the step of reversing the rotation of the fan, the method comprises the further step of switching off the heating means for a predetermined period of time corresponding to the period during which the fan is rotated in a reverse direction and in that the method comprises the step of adding a predetermined amount of water in the condensing means.
Piece of seating furniture (1, 2) with a back rest and a seating surface, in which the seating surface is operatively connected to the back rest, in which the piece of seating furniture (1, 2) has a connecting element (10, 11, 40, 41) made in one piece, which is connected to the back rest and the seating surface and is made to act resiliently against a swivelling movement of the back rest, in which the connecting element is made to swivel the seating surface in a predetermined ratio to the swivelling movement of the back rest, so that when the back rest is swivelled the back rest and the seating surface open up from each other with an opening angle, in which the connecting element (10, 11, 40, 41) has at least one U-shaped leaf spring for the seat (12, 13, 14) and at least one U-shaped leaf spring for the rest (16, 18, 23), in which a seat leg of the leaf spring for the seat is connected to the seating surface and a rest leg of the leaf spring for the rest is connected to the back rest, and a long section of a base leg of the leaf spring for the seat is connected to a long section of a base leg of the at least one leaf spring for the rest in the area of a connecting section, in which the seat leg is connected to the rest leg by means of a swivel joint, in which a turning section connecting the legs (12, 14) of the leaf spring for the seat extends radially outwards from the connecting section in the direction of the front side of the piece of seating furniture further than a turning section of the leaf spring for the rest, in which the legs (16, 18) of the leaf spring for the rest are connected to each other through the turning section of the leaf spring for the rest.
Compressor for a gas turbine, in particular of an aircraft engine, comprising a plurality of blade cascades arranged one behind the other in a throughflow direction from a compressor inlet to a compressor outlet (1, 2), wherein at least one upstream or front detuned blade cascade and at least one downstream or rear detuned blade cascade each has at least two blade types that are structurally different from one another, and at least 80% of the rotor blades of a furthest downstream or rearmost or last rotor blade cascade of the compressor, which cascade is arranged downstream of the downstream or rear detuned blade cascade, are structurally identical to one another.
A process for preparing a sheet article, comprising the steps of: a) preparing a wet pre-mixture comprising a water-soluble polymer and a surfactant and having a viscosity of from 1.0 Pa.s (1,000 cps) to 25 Pa.s (25,000 cps) measured at 40°C and 1 s -1; and b) aerating said wet pre-mixture to form an aerated wet pre-mixture having a density of from 0.05 to 0.5 g/ml; and c) forming said aerated wet pre-mixture into a sheet having opposing first and second sides; and d) drying said formed sheet for a drying time of from 1 minute to 60 minutes at a temperature from 70°C to 200°C along a heating direction that forms a temperature gradient decreasing from the first side to the second side of said formed sheet, wherein said heating direction is substantially opposite to the gravitational direction for more than half of the drying time. a) preparing a wet pre-mixture comprising a water-soluble polymer and a surfactant and having a viscosity of from 1.0 Pa.s (1,000 cps) to 25 Pa.s (25,000 cps) measured at 40°C and 1 s -1; and b) aerating said wet pre-mixture to form an aerated wet pre-mixture having a density of from 0.05 to 0.5 g/ml; and c) forming said aerated wet pre-mixture into a sheet having opposing first and second sides; and d) drying said formed sheet for a drying time of from 1 minute to 60 minutes at a temperature from 70°C to 200°C along a heating direction that forms a temperature gradient decreasing from the first side to the second side of said formed sheet, wherein said heating direction is substantially opposite to the gravitational direction for more than half of the drying time.