Method of producing OSB wood-base panels, comprising the steps of: a) providing wood strands having a length between 50 and 200 mm, a width between 5 to 50 mm, and a thickness between 0.1 and 2 mm; b) applying at least one adhesive system to the wood strands, wherein the adhesive system comprises - a polydiphenylmethane diisocyanate (PMDI) adhesive, and - nanoparticles below 500 nm, wherein the nanoparticles are modified with at least one compound of general formula R a SiX (4-a), or of general formula O b X c d R e SiO(4-b-c-d-e)/2, where - X is H, OH or a hydrolyzable moiety selected from the group comprising halogen, alkoxy, carboxyl, amino, monoalkylamino or dialkylamino, aryloxy, acyloxy, alkylcarbonyl, - R is a nonhydrolyzable organic moiety R selected from the group comprising substituted and unsubstituted alkyl, substituted and unsubstituted aryl, substituted and unsubstituted alkenyl, substituted and unsubstituted alkynyl, substituted and unsubstituted cycloalkyl, which may each be interrupted by -O- or -NH-, and - wherein R includes at least one functional group Q selected from a group containing an epoxy, hydroxyl, ether, amino, monoalkylamino, dialkylamino, substituted and unsubstituted anilino, amide, carboxyl, acryloyl, acryloyloxy, methacryloyl, methacryloyloxy, mercapto, cyano, alkoxy, isocyano, aldehyde, alkylcarbonyl, acid anhydride and/or phosphoric acid group, - a is = 1, 2, 3, especially 1, - b, c, d are = 0 or 1, and - e is = 1, 2, 3; wherein the adhesive system is admixed to the wood strands in an amount between 2.2 and 2.5 wt%, preferably between 2.2 and 2.4 wt% based on the wood strands (absolutely dry wood), and c) pressing the wood strands admixed with the adhesive system to form OSB wood-base panels. a) providing wood strands having a length between 50 and 200 mm, a width between 5 to 50 mm, and a thickness between 0.1 and 2 mm; b) applying at least one adhesive system to the wood strands, wherein the adhesive system comprises - a polydiphenylmethane diisocyanate (PMDI) adhesive, and - nanoparticles below 500 nm, wherein the nanoparticles are modified with at least one compound of general formula R a SiX (4-a), or of general formula O b X c d R e SiO(4-b-c-d-e)/2, where - X is H, OH or a hydrolyzable moiety selected from the group comprising halogen, alkoxy, carboxyl, amino, monoalkylamino or dialkylamino, aryloxy, acyloxy, alkylcarbonyl, - R is a nonhydrolyzable organic moiety R selected from the group comprising substituted and unsubstituted alkyl, substituted and unsubstituted aryl, substituted and unsubstituted alkenyl, substituted and unsubstituted alkynyl, substituted and unsubstituted cycloalkyl, which may each be interrupted by -O- or -NH-, and - wherein R includes at least one functional group Q selected from a group containing an epoxy, hydroxyl, ether, amino, monoalkylamino, dialkylamino, substituted and unsubstituted anilino, amide, carboxyl, acryloyl, acryloyloxy, methacryloyl, methacryloyloxy, mercapto, cyano, alkoxy, isocyano, aldehyde, alkylcarbonyl, acid anhydride and/or phosphoric acid group, - a is = 1, 2, 3, especially 1, - b, c, d are = 0 or 1, and - e is = 1, 2, 3; wherein the adhesive system is admixed to the wood strands in an amount between 2.2 and 2.5 wt%, preferably between 2.2 and 2.4 wt% based on the wood strands (absolutely dry wood), and - a polydiphenylmethane diisocyanate (PMDI) adhesive, and - nanoparticles below 500 nm, wherein the nanoparticles are modified with at least one compound of general formula R a SiX (4-a), or of general formula O b X c d R e SiO(4-b-c-d-e)/2, where - X is H, OH or a hydrolyzable moiety selected from the group comprising halogen, alkoxy, carboxyl, amino, monoalkylamino or dialkylamino, aryloxy, acyloxy, alkylcarbonyl, - R is a nonhydrolyzable organic moiety R selected from the group comprising substituted and unsubstituted alkyl, substituted and unsubstituted aryl, substituted and unsubstituted alkenyl, substituted and unsubstituted alkynyl, substituted and unsubstituted cycloalkyl, which may each be interrupted by -O- or -NH-, and - wherein R includes at least one functional group Q selected from a group containing an epoxy, hydroxyl, ether, amino, monoalkylamino, dialkylamino, substituted and unsubstituted anilino, amide, carboxyl, acryloyl, acryloyloxy, methacryloyl, methacryloyloxy, mercapto, cyano, alkoxy, isocyano, aldehyde, alkylcarbonyl, acid anhydride and/or phosphoric acid group, - a is = 1, 2, 3, especially 1, - b, c, d are = 0 or 1, and - e is = 1, 2, 3; - X is H, OH or a hydrolyzable moiety selected from the group comprising halogen, alkoxy, carboxyl, amino, monoalkylamino or dialkylamino, aryloxy, acyloxy, alkylcarbonyl, - R is a nonhydrolyzable organic moiety R selected from the group comprising substituted and unsubstituted alkyl, substituted and unsubstituted aryl, substituted and unsubstituted alkenyl, substituted and unsubstituted alkynyl, substituted and unsubstituted cycloalkyl, which may each be interrupted by -O- or -NH-, and - wherein R includes at least one functional group Q selected from a group containing an epoxy, hydroxyl, ether, amino, monoalkylamino, dialkylamino, substituted and unsubstituted anilino, amide, carboxyl, acryloyl, acryloyloxy, methacryloyl, methacryloyloxy, mercapto, cyano, alkoxy, isocyano, aldehyde, alkylcarbonyl, acid anhydride and/or phosphoric acid group, - a is = 1, 2, 3, especially 1, - b, c, d are = 0 or 1, and - e is = 1, 2, 3; c) pressing the wood strands admixed with the adhesive system to form OSB wood-base panels.