mhurhangee/ep-ind-claims huggingface dataset:
A method for synchronizing timing among test network interface cards (202, 206) in a network equipment test device, the method comprising: at a management network interface card in a network equipment test device, obtaining or generating a clock; generating and sending timing synchronization measurement signals from a timing synchronizer within the network equipment test device to the management network interface card and a test network interface card in the network equipment test device; recording times of receipt of the timing synchronization measurement signals at the management network interface card and the test network interface card wherein the times of receipt of the timing synchronization measurement signals are respectively recorded using the clock of the management network interface card and a clock of the test network interface card; and reporting the times of receipt of the timing synchronization signals from the management network interface card and the test network interface card to the timing synchronizer for computing, by the timing synchronizer and by using the times of receipt of the timing synchronization signals, a frequency adjustment factor and a phase offset; reporting, by the timing synchronizer, the frequency adjustment factor and the phase offset to the test network interface card, adjusting the clock of the test network interface card using the frequency adjustment factor and the phase offset. at a management network interface card in a network equipment test device, obtaining or generating a clock; generating and sending timing synchronization measurement signals from a timing synchronizer within the network equipment test device to the management network interface card and a test network interface card in the network equipment test device; recording times of receipt of the timing synchronization measurement signals at the management network interface card and the test network interface card wherein the times of receipt of the timing synchronization measurement signals are respectively recorded using the clock of the management network interface card and a clock of the test network interface card; and reporting the times of receipt of the timing synchronization signals from the management network interface card and the test network interface card to the timing synchronizer for computing, by the timing synchronizer and by using the times of receipt of the timing synchronization signals, a frequency adjustment factor and a phase offset; reporting, by the timing synchronizer, the frequency adjustment factor and the phase offset to the test network interface card, adjusting the clock of the test network interface card using the frequency adjustment factor and the phase offset.
A method of generating a radio signal for transmitting a protocol data unit, PDU, in a radio network, wherein the PDU includes a first portion and a second portion, the method comprising or triggering the steps of: amplifying a first signal indicative of the first portion of the PDU for radio transmission using a power amplifier in a first operating state; switching the power amplifier from the first operating state to a second operating state different from the first operating state; and amplifying a second signal indicative of the second portion of the PDU for radio transmission using the power amplifier in the second operating state, wherein a first bandwidth of the first signal is greater than a second bandwidth of the second signal. amplifying a first signal indicative of the first portion of the PDU for radio transmission using a power amplifier in a first operating state; switching the power amplifier from the first operating state to a second operating state different from the first operating state; and amplifying a second signal indicative of the second portion of the PDU for radio transmission using the power amplifier in the second operating state, wherein a first bandwidth of the first signal is greater than a second bandwidth of the second signal.
Bearing assembly for mounting a rotating component, comprising a bearing housing and the rotating component, a part of a plain bearing (3, 4) being arranged in the bearing housing and a part of the plain bearing (3, 4) being arranged on the rotating component, that part of the plain bearing (3, 4) which is arranged in the bearing housing being formed in one piece with the bearing housing, the part of the plain bearing (3, 4) having a sliding surface formed spherically in radial section, characterized in that that part of the plain bearing (3, 4) which is arranged on the rotating component is arranged displaceably in the axial direction (a) of the rotating component by means of a slide-and-push fit, fastening flanges being arranged in the two axially end-face end regions of the rotating component, the outside diameter of the fastening flanges being selected such that, in the event of axial displacement of the rotating component in relation to the bearing housing, the fastening flange can butt against an end face of the bearing housing.
A lead connector for an electrical stimulator system, the connector comprising: a base having a cable port positioned within a first sidewall and a lead port positioned within a second sidewall; a cover, selectively attachable to the base, so as to define an internal cavity, the cover having a cable securing boss that is positioned proximate to the cable port when the cover is attached to the base; and a contact blade, held between the cover and the base when the cover is attached to the base, the contact blade having a flattened angled portion and an extension portion protruding into the internal cavity so as provide electrical contact between a cable inserted through the cable port and a lead inserted through the lead port. a base having a cable port positioned within a first sidewall and a lead port positioned within a second sidewall; a cover, selectively attachable to the base, so as to define an internal cavity, the cover having a cable securing boss that is positioned proximate to the cable port when the cover is attached to the base; and a contact blade, held between the cover and the base when the cover is attached to the base, the contact blade having a flattened angled portion and an extension portion protruding into the internal cavity so as provide electrical contact between a cable inserted through the cable port and a lead inserted through the lead port.
A lancing device comprising: a reciprocating lancet carrier traversing, in use, a linear path of travel along a lancing stroke; and a drive spring (80, 180) and a return spring (82,182) the drive spring (80,180) being stiffer than the return spring (82,182), configured for operating together as a drive mechanism to drive and return the lancet carrier along the lancing stroke upon triggering of the lancing device; the device being characterized in that the drive spring (80; 180) and return spring (82; 182) are torsion springs laterally offset from the lancing stroke path of travel of the lancet carrier. a reciprocating lancet carrier traversing, in use, a linear path of travel along a lancing stroke; and a drive spring (80, 180) and a return spring (82,182) the drive spring (80,180) being stiffer than the return spring (82,182), configured for operating together as a drive mechanism to drive and return the lancet carrier along the lancing stroke upon triggering of the lancing device; the device being characterized in that the drive spring (80; 180) and return spring (82; 182) are torsion springs laterally offset from the lancing stroke path of travel of the lancet carrier.
Method for producing acrylate-based pressure sensitive adhesives, in which acrylate-based polymers are produced, wherein first a controlled radical polymerization reaction of an initial reaction charge comprising at least one acrylate-based monomer is carried out in the presence of at least one chain transfer agent having at least one functional group S-C=X, where X = S, 0 or N, the CTA being selected from the group encompassing dithioesters, dithiocarbonates, dithiocarbamates, trithiocarbonates, imidodithiocarbonates, and xanthates ("RAFT CTAs"), the CTA molecules being incorporated into the polymer chains that form in such a way that the polymer chains in question have at least one functional group of the incorporated CTA, characterized in that at least one chemical compound which has at least two conjugated double bonds (referred to hereinafter as "conjugated diene") is contacted with the polymers thus obtained, so that hetero-Diels-Alder reactions are brought about between the double bonds C=X of the functional groups S-C=X incorporated into the polymer chains and the conjugated double bonds of the conjugated diene, and wherein the acrylate-based polymers obtained are used as pressure sensitive adhesives or further-processed to pressure sensitive adhesives.
Depressurizing method for a cabin of an aircraft on the ground from the outer side of the aircraft, using a depressurizing system comprising a venting valve which can be actuated between an open position and a closed position by means of a shutter and which is connected in fluid terms, via connection means (34a, 34b), to a vacuum pump, the aircraft being provided with a protection valve against excess pressure in the cabin which is connected to a pressure tap port, characterized in that the method comprises the steps involving: - a fluid connection, via the connection means (34a, 34b), of the venting valve to the pressure tap port of the aircraft, the shutter being in an open position; - a movement of the shutter of the venting valve from the open position to the closed position thereof; and - activation of the vacuum pump in order to produce a reduced pressure in the inner volume of the connection means (34a, 34b) and the venting valve in order to generate a reduced pressure in the region of the pressure tap port of the aircraft. - a fluid connection, via the connection means (34a, 34b), of the venting valve to the pressure tap port of the aircraft, the shutter being in an open position; - a movement of the shutter of the venting valve from the open position to the closed position thereof; and - activation of the vacuum pump in order to produce a reduced pressure in the inner volume of the connection means (34a, 34b) and the venting valve in order to generate a reduced pressure in the region of the pressure tap port of the aircraft.
A protective packaging formation device, comprising: an inflation assembly having a fluid conduit that directs fluid between first and second overlapping plies (105, 107) of a web material; a driving mechanism that drives the web material in a downstream direction through an arcuate pinch zone; and a sealing mechanism that includes a heating element including a thin film heating element or a foil heater that includes a wide cross-section portion and a reduced cross-section portion, the size of the cross-sections selected such that the reduced cross-section portion produces high temperature zone that outputs sufficient heat to heat seal the plies to create a longitudinal seal that seals the first and second plies together, trapping the fluid therebetween as the driving mechanism drives the web material past the heating element in the downstream direction. an inflation assembly having a fluid conduit that directs fluid between first and second overlapping plies (105, 107) of a web material; a driving mechanism that drives the web material in a downstream direction through an arcuate pinch zone; and a sealing mechanism that includes a heating element including a thin film heating element or a foil heater that includes a wide cross-section portion and a reduced cross-section portion, the size of the cross-sections selected such that the reduced cross-section portion produces high temperature zone that outputs sufficient heat to heat seal the plies to create a longitudinal seal that seals the first and second plies together, trapping the fluid therebetween as the driving mechanism drives the web material past the heating element in the downstream direction.
A system for monitoring the health of a device that is acoustically coupled to a pipe, wherein the device causes unsteady pressures to be generated in a fluid flowing in the pipe, the system comprising: an array of pressure sensors (15, 16, 17, 18) disposed along the pipe to measure unsteady pressures within the pipe, each of the sensors providing a pressure signal (P 1 (t), P 2 (t), P 3 (t), P 4 (t)); and a signal processor, which is configured for receiving the pressure signals (P 1 (t), P 2 (t), P 3 (t), P 4 (t)) provided by the pressure sensors (15, 16, 17, 18); characterized in that the array of pressure sensors (15, 16, 17, 18) is disposed along the pipe downstream of the device and in that the signal processor is further configured for: applying flow logic to said pressure signals (P 1 (t), P 2 (t), P 3 (t), P 4 (t)) for determining a parameter of the fluid; providing the determined parameter of the fluid as a flow signal, and applying one or more of the pressure signals (P 1 (t), P 2 (t), P 3 (t), P 4 (t)) for diagnosing the health of the device and providing a diagnostic output signal indicative of the health of the device; wherein the parameter of the fluid includes at least speed of sound in the fluid and the signal processor includes flow logic configured for determining a slope of an acoustic ridge in a k-ω plane to determine the speed of sound propagating through the fluid. an array of pressure sensors (15, 16, 17, 18) disposed along the pipe to measure unsteady pressures within the pipe, each of the sensors providing a pressure signal (P 1 (t), P 2 (t), P 3 (t), P 4 (t)); and a signal processor, which is configured for applying flow logic to said pressure signals (P 1 (t), P 2 (t), P 3 (t), P 4 (t)) for determining a parameter of the fluid; providing the determined parameter of the fluid as a flow signal, and applying one or more of the pressure signals (P 1 (t), P 2 (t), P 3 (t), P 4 (t)) for diagnosing the health of the device and providing a diagnostic output signal indicative of the health of the device;
A method for detection of basal-like breast cancer in a patient sample, comprising: detecting in the patient sample the presence of antibodies to at least two tumor antigens, wherein the at least two tumor antigens are selected from the group consisting of: NY-ESO-1 (CTAG1B), P53, NY-ESO-2 (CTAG2), RNF216, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, and TRIM21
A robot system, comprising: a robot including a swing device which swings about a rotation axis orthogonal to an installation plane, and a plurality of robot arms each connected to the swing device; and a control unit which controls the robot so as to keep a control point of at least one robot arm of the plurality of robot arms at the same position in the same posture during a time period between before and after a swing of the swing device. a robot including a swing device which swings about a rotation axis orthogonal to an installation plane, and a plurality of robot arms each connected to the swing device; and a control unit which controls the robot so as to keep a control point of at least one robot arm of the plurality of robot arms at the same position in the same posture during a time period between before and after a swing of the swing device.
A method for identifying a breast cancer tumor in a subject as likely to metastasize, or likely to have metastasized already, comprising: treating a sample of the tumor obtained from the subject so as to permit determination of mRNA levels or determination of gene expression product levels in the sample; determining the proportion of alternatively spliced mRNA isoforms of the following human genes relative to the total mRNA isoforms of the following human genes in the sample or the proportion of alternatively spliced gene expression products of the following human genes relative to the total gene expression products of the following human genes in the sample: CD44, NUMB, FAM62B, SLK, ENAH, H2AFY, and OSBPL8; and/or SCRIB, CLSTN1, MLPH, and TXNDC14 and/or CTNND1; wherein determination of a proportion of alternatively spliced mRNA isoforms, or alternatively spliced gene expression products, respectively, for each of CD44, NUMB, FAM62B, SLK, ENAH, H2AFY, and OSBPL8, equal to, or greater than, a control proportion indicates that the breast cancer tumor is not likely to metastasize or is not likely to have metastasized already, and wherein determination of a proportion of alternatively spliced mRNA isoforms, or alternatively spliced gene expression products, respectively, for each of SCRIB, CLSTN1, MLPH, and TXNDC14 and/or CTNND1 equal to, or greater than, a control proportion indicates that the breast cancer tumor is likely to metastasize or is likely to have metastasized already. treating a sample of the tumor obtained from the subject so as to permit determination of mRNA levels or determination of gene expression product levels in the sample; determining the proportion of alternatively spliced mRNA isoforms of the following human genes relative to the total mRNA isoforms of the following human genes in the sample or the proportion of alternatively spliced gene expression products of the following human genes relative to the total gene expression products of the following human genes in the sample: CD44, NUMB, FAM62B, SLK, ENAH, H2AFY, and OSBPL8; and/or SCRIB, CLSTN1, MLPH, and TXNDC14 and/or CTNND1; CD44, NUMB, FAM62B, SLK, ENAH, H2AFY, and OSBPL8; and/or SCRIB, CLSTN1, MLPH, and TXNDC14 and/or CTNND1; wherein determination of a proportion of alternatively spliced mRNA isoforms, or alternatively spliced gene expression products, respectively, for each of CD44, NUMB, FAM62B, SLK, ENAH, H2AFY, and OSBPL8, equal to, or greater than, a control proportion indicates that the breast cancer tumor is not likely to metastasize or is not likely to have metastasized already, and wherein determination of a proportion of alternatively spliced mRNA isoforms, or alternatively spliced gene expression products, respectively, for each of SCRIB, CLSTN1, MLPH, and TXNDC14 and/or CTNND1 equal to, or greater than, a control proportion indicates that the breast cancer tumor is likely to metastasize or is likely to have metastasized already.
A liquid formulation comprising from 1% (w/w) to 10% sirolimus or a pharmaceutically acceptable salt thereof for use in a method of treating persistent intraretinal or subretinal edema due to exudative AMD in a human subject, the method comprising: administering an effective amount of said liquid formulation to the human subject by intravitreal injection to treat persistent intraretinal or subretinal edema, wherein the human subject has persistent intraretinal or subretinal edema due to exudative AMD despite previous intravitreal treatment with an anti-VEGF monoclonal antibody or VEGF-binding fragment thereof, and the effective amount of the liquid formulation comprises from 200 to 900 μg sirolimus. administering an effective amount of said liquid formulation to the human subject by intravitreal injection to treat persistent intraretinal or subretinal edema, wherein the human subject has persistent intraretinal or subretinal edema due to exudative AMD despite previous intravitreal treatment with an anti-VEGF monoclonal antibody or VEGF-binding fragment thereof, and the effective amount of the liquid formulation comprises from 200 to 900 μg sirolimus.
A hybrid tomato plant comprising a structurally intact and functional wild-type SFT gene copy and a mutated sft copy, wherein the SFT gene comprises the nucleic acid sequence set forth in SEQ ID NO:2 and the mutation in the sft copy is such that it reduces SFT gene function when homozygous, and wherein said hybrid tomato plant shows at least one yield-related heterotic phenotype compared to a homozygous plant having two functional wild-type copies of the SFT gene, the at least one heterosis related phenotype is a yield-affecting trait selected from the group consisting of vegetative growth rate, plant weight, flowering time, inflorescence number, number of flowers per inflorescence, timing of fruit or grain set, fruit or grain weight, tolerance to biotic stress and tolerance to abiotic stress, wherein said hybrid tomato plant is not exclusively obtained by an essentially biological process.
A pharmaceutical composition for topical administration to a mammal comprising two or more pharmaceutically acceptable excipients and a therapeutically effective amount of a spiro-oxindole compound having the following formula: or a pharmaceutically acceptable salt thereof; wherein the two or more pharmaceutically acceptable excipients are selected from: (a) one or more solvents selected from PEG 400 at concentration of from 30% w/w to 70% w/w or PEG 3350 at a concentration of from 10% w/w to 50% w/w; (b) one or more penetration enhancing agents selected from diethylene glycol monoethyl ether at a concentration of from 2% w/w to 25% w/w, oleyl alcohol at a concentration of from 1 % w/w to 10% w/w or isopropyl myristate at a concentration of from 1 % w/w to 25% w/w; (c) one or more stiffening agents selected from stearyl alcohol at a concentration of from 0.1 % w/w to 10% w/w; (d) an ointment base selected from PEG 400 at concentration of from 30% w/w to 70% w/w or PEG 3350 at a concentration of from 10% w/w to 50% w/w; and (e) one or more antioxidants selected from butylated hydroxytoluene at a concentration of from 0.01 % w/w to 2% w/w. (a) one or more solvents selected from PEG 400 at concentration of from 30% w/w to 70% w/w or PEG 3350 at a concentration of from 10% w/w to 50% w/w; (b) one or more penetration enhancing agents selected from diethylene glycol monoethyl ether at a concentration of from 2% w/w to 25% w/w, oleyl alcohol at a concentration of from 1 % w/w to 10% w/w or isopropyl myristate at a concentration of from 1 % w/w to 25% w/w; (c) one or more stiffening agents selected from stearyl alcohol at a concentration of from 0.1 % w/w to 10% w/w; (d) an ointment base selected from PEG 400 at concentration of from 30% w/w to 70% w/w or PEG 3350 at a concentration of from 10% w/w to 50% w/w; and (e) one or more antioxidants selected from butylated hydroxytoluene at a concentration of from 0.01 % w/w to 2% w/w.
An extendable embarking aid of an entrance door of a passenger transport vehicle with a roller system, wherein - the embarking aid can be moved from a rest position into a use position and back, - guiding means are provided which respectively extend laterally of the embarking aid in the extending/retraction direction, and - the embarking aid is guided by means of rollers in the guiding means, characterized in that at least the axis of one of the rollers can be moved vertically relative to the embarking aid, whereby the embarking aid can be moved in the vertical direction relative to the guiding means of the movable roller in such a way that the embarking aid, in the case of a vertical load (F b) from above, can be supported on at least one stationary component of the passenger transport vehicle independently from the rollers, so that the vertical load (F b) is not held by the rollers but is transmitted via the support into this stationary component of the passenger transport vehicle. - the embarking aid can be moved from a rest position into a use position and back, - guiding means are provided which respectively extend laterally of the embarking aid in the extending/retraction direction, and - the embarking aid is guided by means of rollers in the guiding means, characterized in that at least the axis of one of the rollers can be moved vertically relative to the embarking aid, whereby the embarking aid can be moved in the vertical direction relative to the guiding means of the movable roller in such a way that the embarking aid, in the case of a vertical load (F b) from above, can be supported on at least one stationary component of the passenger transport vehicle independently from the rollers, so that the vertical load (F b) is not held by the rollers but is transmitted via the support into this stationary component of the passenger transport vehicle.