mhurhangee/ep-ind-claims huggingface dataset:
A formulation, product of manufacture or composition for use in the treatment of a retinal disease or condition in a subject, wherein the formulation, product of manufacture or composition comprises a cell population comprising non-immortal human retinal progenitor cells, wherein the formulation is made by mechanically and/or enzymatically dissociating a sample of human retinal tissue obtained from a human at about 12 weeks to about 28 weeks gestational age to generate a dissociated suspension of cells and cell clusters; and culturing the dissociated suspension and/or cell clusters in serum-free media in culture flasks or plates coated with a xeno-free fibronectin or a laminin for: (i) about 10 to 30 passages, or (ii) no more than 10 passages, wherein the cells are passaged by treating with an enzyme at each passage to dissociate the cells and the culture media is supplemented with vitamin C or the vitamin C is added every 1 to 2 days, wherein the vitamin C is added in an amount to have an initial concentration of between about O.Olmg/ml and 0.5 mg/ml, thereby making non-immortal human retinal progenitor cells, wherein the non-immortal human retinal progenitor cells express one or more markers selected from the group consisting of nestin, Sox2, Ki-67, MHC Class I, and Fas/CD95, wherein nestin is expressed by greater than 90% of the cells in the population, wherein Sox2 is expressed by greater than 80% of the cells in the population, wherein Ki-67 is expressed by % greater than 30% of the cells in the population, wherein MHC Class I is expressed by greater than 70% of the cells in the population, and wherein Fas/CD95 is expressed by greater than 30% of the cells in the population. (i) about 10 to 30 passages, or (ii) no more than 10 passages,
A method for controlling the speed of a vehicle, said vehicle comprising a drive train, said drive train comprising a power supply and an automatic transmission arrangement which comprises a power split assembly which in turn comprises a step ratio power flow path and an infinitely variable ratio power flow path for driving said vehicle, said vehicle comprising a predetermined preferred speed set, wherein a power loss of said drive train is equal to or below a predetermined power loss within said predetermined preferred speed set, said method comprising: - determining whether or not a substantially constant speed of the vehicle is requested; - if it is determined that a substantially constant speed is requested, determining whether the requested speed lies within or outside of said predetermined preferred speed set, and - if it is determined that the requested speed lies outside of said predetermined speed set, automatically adjusting the speed of the vehicle to a new, different substantially constant vehicle speed that is within said predetermined speed set such that at least one value in said predetermined preferred speed set corresponds to at least one condition of said transmission arrangement in which at least a 80%, preferably at least 90% of the power flows through said step ratio power flow path of said power split assembly. - determining whether or not a substantially constant speed of the vehicle is requested; - if it is determined that a substantially constant speed is requested, determining whether the requested speed lies within or outside of said predetermined preferred speed set, and - if it is determined that the requested speed lies outside of said predetermined speed set, automatically adjusting the speed of the vehicle to a new, different substantially constant vehicle speed that is within said predetermined speed set such that at least one value in said predetermined preferred speed set corresponds to at least one condition of said transmission arrangement in which at least a 80%, preferably at least 90% of the power flows through said step ratio power flow path of said power split assembly.
Power cable for transporting an alternate current I at a maximum allowable working conductor temperature T comprising: - at least two cores stranded together according to a core stranding lay and a core stranding pitch A, each core comprising an electric conductor having a cross section area S and conductor losses when the current I is transported; - an armour surrounding the at least two cores, said armour comprising one layer of a plurality of metal wires wound around the cores according to a helical armour winding lay and an armour winding pitch B, said armour having armour losses when the current I is transported; said conductor losses and armour losses contributing to overall cable losses determining the maximum allowable working conductor temperature T; wherein the helical armour winding lay has the same direction as the core stranding lay, and the cross section area S is such to cause the cable to operate at the maximum allowable working conductor temperature T while transporting the alternate current I with armour losses equal to or lower than 30% of the overall cable losses, characterized in that the armour winding pitch B and the core stranding pitch A are such that a crossing pitch C is higher or equal to 3A, the armour winding pitch B differing from the core stranding pitch A by at least 10%, and the crossing pitch C being defined by the following relationship: C = 1 1 A − 1 B. - at least two cores stranded together according to a core stranding lay and a core stranding pitch A, each core comprising an electric conductor having a cross section area S and conductor losses when the current I is transported; - an armour surrounding the at least two cores, said armour comprising one layer of a plurality of metal wires wound around the cores according to a helical armour winding lay and an armour winding pitch B, said armour having armour losses when the current I is transported; said conductor losses and armour losses contributing to overall cable losses determining the maximum allowable working conductor temperature T;
A power conversion system comprising: a reactor in which hydrogen and an aromatic hydrocarbon are chemically bound under a heating condition; a decomposer decomposing a product prepared via chemical binding between the hydrogen and the aromatic hydrocarbon into hydrogen and the aromatic hydrocarbon again under a heating condition; and a compression ignition-type internal-combustion engine feeding exhaust gas as a heat source to the reactor and the decomposer when the reactor and the decomposer are heated, characterised in that the compression ignition-type internal-combustion engine includes: a first valve arranged in a flow path for feeding air; a second valve arranged in a flow path for feeding oxygen; a third valve arranged in a flow path for feeding hydrogen; a fourth valve arranged in a flow path for feeding recirculated exhaust gas; and a fifth valve arranged in a flow path for feeding coolant which cools the recirculated exhaust gas fed to the compression ignition-type internal-combustion engine, by heat exchange between the coolant and the recirculated exhaust gas. a reactor in which hydrogen and an aromatic hydrocarbon are chemically bound under a heating condition; a decomposer decomposing a product prepared via chemical binding between the hydrogen and the aromatic hydrocarbon into hydrogen and the aromatic hydrocarbon again under a heating condition; and a compression ignition-type internal-combustion engine feeding exhaust gas as a heat source to the reactor and the decomposer when the reactor and the decomposer are heated, characterised in that the compression ignition-type internal-combustion engine includes: a first valve arranged in a flow path for feeding air; a second valve arranged in a flow path for feeding oxygen; a third valve arranged in a flow path for feeding hydrogen; a fourth valve arranged in a flow path for feeding recirculated exhaust gas; and a fifth valve arranged in a flow path for feeding coolant which cools the recirculated exhaust gas fed to the compression ignition-type internal-combustion engine, by heat exchange between the coolant and the recirculated exhaust gas. a first valve arranged in a flow path for feeding air; a second valve arranged in a flow path for feeding oxygen; a third valve arranged in a flow path for feeding hydrogen; a fourth valve arranged in a flow path for feeding recirculated exhaust gas; and a fifth valve arranged in a flow path for feeding coolant which cools the recirculated exhaust gas fed to the compression ignition-type internal-combustion engine, by heat exchange between the coolant and the recirculated exhaust gas.
A roll (300, 405, 510) of laminated material (200, 425), the roll comprising: a plurality of layers of the laminated material (200, 425) wound around a core, each layer comprising: an ion-exchange resin layer (205, 305, 420) having inner (240, 320) and outer (235, 325) surfaces; a release film (225, 310) having inner (250, 330) and outer (245, 335) surfaces, the outer surface (245, 335) of the release film (225, 310) being bonded to the inner surface (240, 320) of the ion-exchange resin layer (205, 305); and a base layer (230, 315) having inner (260, 340) and outer (255, 345) surfaces, the outer surface (255, 345) of the base layer (230, 315) being bonded to the inner surface (250, 330) of the release film (225, 310), wherein a first layer of the plurality of layers comprises the inner surface (260, 340) of the base layer (230, 315) contacting an outer surface of the core and a second layer of the plurality of layers comprises the inner surface of the base layer (230, 315) contacting the outer surface (235, 325) of the ion-exchange resin layer (205, 305, 420) from the first layer. a plurality of layers of the laminated material (200, 425) wound around a core, each layer comprising: an ion-exchange resin layer (205, 305, 420) having inner (240, 320) and outer (235, 325) surfaces; a release film (225, 310) having inner (250, 330) and outer (245, 335) surfaces, the outer surface (245, 335) of the release film (225, 310) being bonded to the inner surface (240, 320) of the ion-exchange resin layer (205, 305); and a base layer (230, 315) having inner (260, 340) and outer (255, 345) surfaces, the outer surface (255, 345) of the base layer (230, 315) being bonded to the inner surface (250, 330) of the release film (225, 310), wherein a first layer of the plurality of layers comprises the inner surface (260, 340) of the base layer (230, 315) contacting an outer surface of the core and a second layer of the plurality of layers comprises the inner surface of the base layer (230, 315) contacting the outer surface (235, 325) of the ion-exchange resin layer (205, 305, 420) from the first layer. an ion-exchange resin layer (205, 305, 420) having inner (240, 320) and outer (235, 325) surfaces; a release film (225, 310) having inner (250, 330) and outer (245, 335) surfaces, the outer surface (245, 335) of the release film (225, 310) being bonded to the inner surface (240, 320) of the ion-exchange resin layer (205, 305); and a base layer (230, 315) having inner (260, 340) and outer (255, 345) surfaces, the outer surface (255, 345) of the base layer (230, 315) being bonded to the inner surface (250, 330) of the release film (225, 310), wherein a first layer of the plurality of layers comprises the inner surface (260, 340) of the base layer (230, 315) contacting an outer surface of the core and a second layer of the plurality of layers comprises the inner surface of the base layer (230, 315) contacting the outer surface (235, 325) of the ion-exchange resin layer (205, 305, 420) from the first layer.
A degasser for removing molecules of gasses entrapped or dissolved in a processing liquid, the degasser comprising: a vacuum chamber having one or more than one vacuum chamber wall (24, 25); one or more than one fluid inlet and one or more than one fluid outlet through which the processing liquid is respectively passed into and out of the vacuum chamber, the one or more than one inlet and the one or more than one outlet penetrating at least one of the vacuum chamber walls (24, 25); two or more separators located inside the vacuum chamber and being configured to be pervious to the molecules of the entrapped or dissolved gas but impervious to the processing liquid; at least one vacuum for applying through a vacuum port a pressure differential across the two or more separators to cause the molecules of the entrapped or dissolved gas to leave the processing liquid and to permeate through the two or more separators thereby removing the entrapped or dissolved gas from the processing liquid; and one feed line in fluid communication with two or more separators; and a collection line in fluid communication with two or more separators; and at least one valve in the feed line and at least one valve in the collection line that when closed isolate a flow path comprising an inlet, a separator, and an outlet from one or more other flow paths comprising one or more than one other separator in the degasser. a vacuum chamber having one or more than one vacuum chamber wall (24, 25); one or more than one fluid inlet and one or more than one fluid outlet through which the processing liquid is respectively passed into and out of the vacuum chamber, the one or more than one inlet and the one or more than one outlet penetrating at least one of the vacuum chamber walls (24, 25); two or more separators located inside the vacuum chamber and being configured to be pervious to the molecules of the entrapped or dissolved gas but impervious to the processing liquid; at least one vacuum for applying through a vacuum port a pressure differential across the two or more separators to cause the molecules of the entrapped or dissolved gas to leave the processing liquid and to permeate through the two or more separators thereby removing the entrapped or dissolved gas from the processing liquid; and one feed line in fluid communication with two or more separators; and a collection line in fluid communication with two or more separators; and at least one valve in the feed line and at least one valve in the collection line that when closed isolate a flow path comprising an inlet, a separator, and an outlet from one or more other flow paths comprising one or more than one other separator in the degasser.
Iron -2,4-dioxo-1-carbonyl complex compounds containing at least one ligand of the formula: wherein the arrows each represent a coordinate bond to one or different iron atoms, R 1 is selected from the group consisting of - optionally substituted alkyl, - optionally substituted alkoxy and - optionally substituted alkoxycarbonyl, R 2 is selected from the group consisting of - hydrogen, - optionally substituted alkyl and - halogen, or R 1 and R 2 together with the carbon atoms to which they are attached, represent an optionally substituted 5- or 6-membered ring which may optionally have one or more heteroatoms, R 3 is selected from the group consisting of - optionally substituted alkyl, - optionally substituted alkoxy, - optionally substituted amino and - hydroxy, or pharmaceutically acceptable salts thereof for the use in the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias. - optionally substituted alkyl, - optionally substituted alkoxy and - optionally substituted alkoxycarbonyl, - hydrogen, - optionally substituted alkyl and - halogen, or - optionally substituted alkyl, - optionally substituted alkoxy, - optionally substituted amino and - hydroxy,
An unmanned aerial vehicle (UAV; 200, 400) comprising a payload delivery system (410, 500), the payload delivery system comprising: a tether (224, 402, 502) disposed on a spool, wherein a first end of the tether is non-fixedly wound on the spool; a payload coupling apparatus (226, 412, 800) structured to mechanically couple a second end of the tether to a payload (228, 408, 510); a motor (222, 512) arranged in the UAV, wherein operating the motor in a first mode and a second mode respectively counters and assists unwinding of the tether due to gravity; and a control system configured to control the motor to carry out tethered delivery of the payload; wherein the control system is further configured to, during the process of delivering the payload to a target location and while the UAV is in flight: determine that both (a) an unwound length of the tether is greater than a threshold length and (b) a motor current of the motor is greater than a threshold current for at least a predetermined timeout period, and responsively cause the UAV to initiate a flight to a different location and control the motor to allow the tether to unwind, such that the flight of the UAV unwinds the tether and separates the first end of the tether from the spool, thereby releasing the tether from the UAV. a tether (224, 402, 502) disposed on a spool, wherein a first end of the tether is non-fixedly wound on the spool; a payload coupling apparatus (226, 412, 800) structured to mechanically couple a second end of the tether to a payload (228, 408, 510); a motor (222, 512) arranged in the UAV, wherein operating the motor in a first mode and a second mode respectively counters and assists unwinding of the tether due to gravity; and a control system configured to control the motor to carry out tethered delivery of the payload; wherein the control system is further configured to, during the process of delivering the payload to a target location and while the UAV is in flight: determine that both (a) an unwound length of the tether is greater than a threshold length and (b) a motor current of the motor is greater than a threshold current for at least a predetermined timeout period, and responsively cause the UAV to initiate a flight to a different location and control the motor to allow the tether to unwind, such that the flight of the UAV unwinds the tether and separates the first end of the tether from the spool, thereby releasing the tether from the UAV. determine that both (a) an unwound length of the tether is greater than a threshold length and (b) a motor current of the motor is greater than a threshold current for at least a predetermined timeout period, and responsively cause the UAV to initiate a flight to a different location and control the motor to allow the tether to unwind, such that the flight of the UAV unwinds the tether and separates the first end of the tether from the spool, thereby releasing the tether from the UAV.
A process for producing powder particles by atomization of a feed material in the form of an elongated wire, comprising: a) introducing the feed material in a plasma torch via an injection probe; b) moving a forward portion of the feed material into an atomization nozzle of the plasma torch, the atomization nozzle (160, 660) having a channel through which the forward end portion of the wire travels to expose the forward end portion of the elongated wire to a plurality of converging plasma jets; c) surface melting the forward end of the feed material by exposure to the plurality of converging plasma jets formed in the atomization nozzle, wherein surface melting results in molten droplets of the feed material, wherein the droplets cool down and freeze in-flight within a cooling chamber, forming the powder particles. a) introducing the feed material in a plasma torch via an injection probe; b) moving a forward portion of the feed material into an atomization nozzle of the plasma torch, the atomization nozzle (160, 660) having a channel through which the forward end portion of the wire travels to expose the forward end portion of the elongated wire to a plurality of converging plasma jets; c) surface melting the forward end of the feed material by exposure to the plurality of converging plasma jets formed in the atomization nozzle,
Brake disc arrangement having a brake dust particulate filter, having a brake disc and having a brake caliper accommodated on a brake caliper holder via at least one bearing bolt, wherein the brake caliper is mounted floatingly on the brake caliper holder by means of the bearing bolt, and wherein the brake dust particulate filter features a filter housing, characterized in that the filter housing of the brake dust particulate filter is firmly connected to the brake caliper or to the brake caliper holder via the bearing bolt.
An implantable medical device (200; 300) comprising: a mesh defining a first plane, and a film including a first end portion secured to at least a portion of a surface of the mesh and a second extended end portion; characterised in that: the second extended end portion of the film is stationary; the second extended end portion of the film defines a second plane different from the first plane of the mesh; and the first plane defined by the mesh and the second plane defined by the film creates a right angle. a mesh defining a first plane, and a film including a first end portion secured to at least a portion of a surface of the mesh and a second extended end portion; characterised in that: the second extended end portion of the film is stationary; the second extended end portion of the film defines a second plane different from the first plane of the mesh; and the first plane defined by the mesh and the second plane defined by the film creates a right angle. the second extended end portion of the film is stationary; the second extended end portion of the film defines a second plane different from the first plane of the mesh; and the first plane defined by the mesh and the second plane defined by the film creates a right angle.
Trim profile covering fixture with at least one side covering element with a longitudinal axis, for a trim profile of a movable furniture component, in particular a drawer, wherein the side covering element has at least one mounting projection (43a, 43b) which may be inserted into an assigned mounting location (32a, 32b) on the trim profile and is held there in the inserted state, wherein the mounting projection (43a, 43b) has at least one clamping jaw (44a, 44b; 45a, 45b) which may be braced by an inner surface of the mounting location (32a, 32b), wherein the mounting projection (43a, 43b) has a base section, on which at least one clamping jaw (44a, 44b, 45a, 45b) is movably mounted using bearing means, wherein the side covering element has at least one mounting interface (54a, 54) for the fixing of a trim fastener, which in turn is used to mount the trim profile on the rest of the movable furniture component, and wherein the at least one trim fastener is attached to the side covering element at the assigned mounting interface (54a, 54b), characterized in that the mounting interface (54a, 54b) is connected to the mounting projection (43a, 43b) in such a way that actuating means serving for bracing of the clamping jaws (44a, 44b, 45a, 45b) also effect the fixing of the trim fastener to the mounting interface (54a, 54b).