A method of processing digital pathology and cytology images for viewing, comprising: electronically generating a plurality of patches of different sub-regions of a region of interest from a digital pathology or cytology whole slide image, WSI; electronically classifying the patches into a plurality of different classes; electronically providing random samples of the patches from each of the different classes; calculating a first positive total cell count, in the WSI or the region of interest, indicating a number of positive cells, wherein positive cells are cells that have a nucleus that is stained and has a positive expression; presenting a plurality of the provided patches as a patch gallery on a display; and accepting user input to electronically interface with the patch gallery, automatically electronically resorting patches in different classifications based on user input to change the classification of one of the patches from its initial classification, then electronically generating a revised confidence interval of the different classification of the patches, and accepting user input to electronically interface with the patch gallery, to perform at least one of: (i) adjust a threshold value of a feature dimension of the patches using an electronic interface input feature on the patch gallery, wherein the feature dimension is a measurable property of a feature in a patch relevant to user interaction for analysis of the WSI; (ii) reduce a parameter span/extent from the parameter span/extent shown for the patches in the patch gallery which electronically updates the patch gallery displayed to include a more narrow extent of the parameter span/extent; (iii) exclude at least one of the patches in the patch gallery which leads to automatically reduce a first positive total cell count by a number corresponding to cells associated with positive cells in the excluded at least one patch; and (iv) select at least one of the patches in the patch gallery wherein the selection triggers to automatically reclassify the selected patch from its classification in the patch gallery. electronically generating a plurality of patches of different sub-regions of a region of interest from a digital pathology or cytology whole slide image, WSI; electronically classifying the patches into a plurality of different classes; electronically providing random samples of the patches from each of the different classes; calculating a first positive total cell count, in the WSI or the region of interest, indicating a number of positive cells, wherein positive cells are cells that have a nucleus that is stained and has a positive expression; presenting a plurality of the provided patches as a patch gallery on a display; and accepting user input to electronically interface with the patch gallery, automatically electronically resorting patches in different classifications based on user input to change the classification of one of the patches from its initial classification, then electronically generating a revised confidence interval of the different classification of the patches, and accepting user input to electronically interface with the patch gallery, to perform at least one of: (i) adjust a threshold value of a feature dimension of the patches using an electronic interface input feature on the patch gallery, wherein the feature dimension is a measurable property of a feature in a patch relevant to user interaction for analysis of the WSI; (ii) reduce a parameter span/extent from the parameter span/extent shown for the patches in the patch gallery which electronically updates the patch gallery displayed to include a more narrow extent of the parameter span/extent; (iii) exclude at least one of the patches in the patch gallery which leads to automatically reduce a first positive total cell count by a number corresponding to cells associated with positive cells in the excluded at least one patch; and (iv) select at least one of the patches in the patch gallery wherein the selection triggers to automatically reclassify the selected patch from its classification in the patch gallery. (i) adjust a threshold value of a feature dimension of the patches using an electronic interface input feature on the patch gallery, wherein the feature dimension is a measurable property of a feature in a patch relevant to user interaction for analysis of the WSI; (ii) reduce a parameter span/extent from the parameter span/extent shown for the patches in the patch gallery which electronically updates the patch gallery displayed to include a more narrow extent of the parameter span/extent; (iii) exclude at least one of the patches in the patch gallery which leads to automatically reduce a first positive total cell count by a number corresponding to cells associated with positive cells in the excluded at least one patch; and (iv) select at least one of the patches in the patch gallery wherein the selection triggers to automatically reclassify the selected patch from its classification in the patch gallery.