A shaft sealing ring for sealing off a media side from an outer side of a shaft arrangement, comprising a sealing portion, which, in the operating state, extends along a sealing axis, and which has a running surface for dynamic sealing contact with a sealing surface of a machine part of the shaft arrangement, wherein the sealing portion is provided with a plurality of profile grooves, which are arranged spaced apart in the direction of the sealing axis and are each open toward the running surface, wherein each profile groove is laterally delimited by a first lateral flank, which is arranged on the media side during operational use of the shaft sealing ring, and by a second lateral flank, which is arranged on the ambient side during operational use, characterized in that (a) the first lateral flank has a straight or substantially straight course in the circumferential direction, the second lateral flank extends bidirectionally in the circumferential direction of the shaft sealing ring axially towards the first lateral flank from each maximum of the flow cross section of the profile groove to a minimum of the flow cross section, and each minimum of a profile groove is arranged in alignment or substantially in alignment with a maximum of the respectively closest profile groove, or (b) the groove depth of the profile groove varies in the circumferential direction of the profile groove in order to form alternate maxima and minima of the flow cross section in the profile groove, and each minimum of a profile groove is arranged in alignment or substantially in alignment with a maximum of the respectively closest profile groove, or (c) at least some of the profile grooves or each profile groove are/is in the form of a closed ring, the flank course of a groove flank of the profile groove varies in the circumferential direction of the profile groove in order to form alternate maxima and minima of the flow cross section in the profile groove, and each minimum of a profile groove is arranged in alignment or substantially in alignment with a maximum of the respectively closest profile groove. wherein the sealing portion is provided with a plurality of profile grooves, which are arranged spaced apart in the direction of the sealing axis and are each open toward the running surface, wherein each profile groove is laterally delimited by a first lateral flank, which is arranged on the media side during operational use of the shaft sealing ring, and by a second lateral flank, which is arranged on the ambient side during operational use, characterized in that (a) the first lateral flank has a straight or substantially straight course in the circumferential direction, the second lateral flank extends bidirectionally in the circumferential direction of the shaft sealing ring axially towards the first lateral flank from each maximum of the flow cross section of the profile groove to a minimum of the flow cross section, and each minimum of a profile groove is arranged in alignment or substantially in alignment with a maximum of the respectively closest profile groove, or (b) the groove depth of the profile groove varies in the circumferential direction of the profile groove in order to form alternate maxima and minima of the flow cross section in the profile groove, and each minimum of a profile groove is arranged in alignment or substantially in alignment with a maximum of the respectively closest profile groove, or (c) at least some of the profile grooves or each profile groove are/is in the form of a closed ring, the flank course of a groove flank of the profile groove varies in the circumferential direction of the profile groove in order to form alternate maxima and minima of the flow cross section in the profile groove, and each minimum of a profile groove is arranged in alignment or substantially in alignment with a maximum of the respectively closest profile groove. (a) the first lateral flank has a straight or substantially straight course in the circumferential direction, the second lateral flank extends bidirectionally in the circumferential direction of the shaft sealing ring axially towards the first lateral flank from each maximum of the flow cross section of the profile groove to a minimum of the flow cross section, and each minimum of a profile groove is arranged in alignment or substantially in alignment with a maximum of the respectively closest profile groove, or (b) the groove depth of the profile groove varies in the circumferential direction of the profile groove in order to form alternate maxima and minima of the flow cross section in the profile groove, and each minimum of a profile groove is arranged in alignment or substantially in alignment with a maximum of the respectively closest profile groove, or (c) at least some of the profile grooves or each profile groove are/is in the form of a closed ring, the flank course of a groove flank of the profile groove varies in the circumferential direction of the profile groove in order to form alternate maxima and minima of the flow cross section in the profile groove, and each minimum of a profile groove is arranged in alignment or substantially in alignment with a maximum of the respectively closest profile groove.