A ophthalmologic replacement cassette configured for a utilization with an ophthalmological apparatus - in particular an interchangeable ophthalmological cassette coming into contact with patient liquid for an ophthalmic surgical device - with: ▪ at least one hard region (41, 42, 43) as housing of the replacement cassette, in particular made of a hard plastic, ▪ at least one soft region (44a, 44b), in particular made of a soft plastic, ∘ wherein the hard region (41, 42, 43) and the soft region (44a, 44b) form inner liquid channels of the replacement cassette, and ∘ wherein the soft region (44a, 44b) forms a cassette-side pressure detection arrangement for determining a liquid pressure in at least one of the liquid channels, characterized in that the pressure detection arrangement in the replacement cassette is configured with: ▪ a pressure chamber, which is connected to one of the liquid channels, ▪ which pressure chamber has a flexible membrane outwardly, and ▪ which flexible membrane peripherally surrounds a coupling element, ▪ wherein the coupling element is configured with an at least partially circumferential recess in the coupling element, which is oriented substantially parallel to the membrane and to an insertion direction of the replacement cassette into the ophthalmological apparatus, which is configured in such a way that, as the replacement cassette is inserted substantially parallel to the membrane into the ophthalmological apparatus, an arm, shaped into a fork, of a force measuring arrangement of the ophthalmological apparatus engages substantially parallel to the membrane into the recess, in such a way that the coupling element is surrounded at least on two sides by the fork-shaped arm and a force effect on the membrane occurring in a direction substantially normal in relation to the membrane is detectable by the force measuring arrangement both in a positive and in a negative direction. ▪ at least one hard region (41, 42, 43) as housing of the replacement cassette, in particular made of a hard plastic, ▪ at least one soft region (44a, 44b), in particular made of a soft plastic, ∘ wherein the hard region (41, 42, 43) and the soft region (44a, 44b) form inner liquid channels of the replacement cassette, and ∘ wherein the soft region (44a, 44b) forms a cassette-side pressure detection arrangement for determining a liquid pressure in at least one of the liquid channels, ∘ wherein the hard region (41, 42, 43) and the soft region (44a, 44b) form inner liquid channels of the replacement cassette, and ∘ wherein the soft region (44a, 44b) forms a cassette-side pressure detection arrangement for determining a liquid pressure in at least one of the liquid channels, ▪ a pressure chamber, which is connected to one of the liquid channels, ▪ which pressure chamber has a flexible membrane outwardly, and ▪ which flexible membrane peripherally surrounds a coupling element, ▪ wherein the coupling element is configured with an at least partially circumferential recess in the coupling element, which is oriented substantially parallel to the membrane and to an insertion direction of the replacement cassette into the ophthalmological apparatus, which is configured in such a way that, as the replacement cassette is inserted substantially parallel to the membrane into the ophthalmological apparatus, an arm, shaped into a fork, of a force measuring arrangement of the ophthalmological apparatus engages substantially parallel to the membrane into the recess, in such a way that the coupling element is surrounded at least on two sides by the fork-shaped arm and a force effect on the membrane occurring in a direction substantially normal in relation to the membrane is detectable by the force measuring arrangement both in a positive and in a negative direction.