A pre-filled blow-fill-seal intradermal injection system, comprising: a BFS bottle defining a collapsible fluid chamber, a neck portion, an exterior flange, and a BFS seal at an end of the neck portion; a connector defining a first connector end and a second connector end, the first connector end comprising an interior seat into which the exterior flange is axially mated, the second connector end comprising a hub bore in which an interior cone and at least one axial track is disposed; a hub member disposed in the hub bore, the hub member comprising a hub body from which a first plurality of elongate legs extend axially outward in a first direction and from which a second plurality of elongate legs extend axially outward in a second direction, the hub member comprising an administration member seat disposed axially therethrough and defining at least one circumferential tab cooperatively shaped and engaged with the axial track of the connector, and the first plurality of elongate legs being engaged with the interior cone in a first position; an administration member retained by the administration member seat and extending through the hub body, the administration member comprising a piercing end and an administration end, with the piercing end being disposed within the hub bore; a piston (650, 850) defining a piston bore within which the administration end of the administration member is disposed and comprising a plurality of axial leg tracks with which the second plurality of elongate legs are engaged; and a shield comprising a body and defining an interior volume in which the piston is slidably disposed, the shield defining an administration member bore therethrough and the shield comprising a plurality of internal shoulder elements aligned with the second plurality of elongate legs; wherein axial force applied to the piston causes the piston and the hub member to advance axially into the hub bore which thereby causes the respective first plurality of elongate legs to travel along an increasing diameter of the interior cone and causes the second plurality of elongate legs to engage with an increasing diameter of the axial leg tracks, which thereby causes the first and second elongate legs to be elastically biased in a radially outward direction, and wherein the advancing of the piston and the hub member causes the piercing end of the administration member to pierce the fluid seal of the BFS bottle. a BFS bottle defining a collapsible fluid chamber, a neck portion, an exterior flange, and a BFS seal at an end of the neck portion; a connector defining a first connector end and a second connector end, the first connector end comprising an interior seat into which the exterior flange is axially mated, the second connector end comprising a hub bore in which an interior cone and at least one axial track is disposed; a hub member disposed in the hub bore, the hub member comprising a hub body from which a first plurality of elongate legs extend axially outward in a first direction and from which a second plurality of elongate legs extend axially outward in a second direction, the hub member comprising an administration member seat disposed axially therethrough and defining at least one circumferential tab cooperatively shaped and engaged with the axial track of the connector, and the first plurality of elongate legs being engaged with the interior cone in a first position; an administration member retained by the administration member seat and extending through the hub body, the administration member comprising a piercing end and an administration end, with the piercing end being disposed within the hub bore; a piston (650, 850) defining a piston bore within which the administration end of the administration member is disposed and comprising a plurality of axial leg tracks with which the second plurality of elongate legs are engaged; and a shield comprising a body and defining an interior volume in which the piston is slidably disposed, the shield defining an administration member bore therethrough and the shield comprising a plurality of internal shoulder elements aligned with the second plurality of elongate legs; wherein axial force applied to the piston causes the piston and the hub member to advance axially into the hub bore which thereby causes the respective first plurality of elongate legs to travel along an increasing diameter of the interior cone and causes the second plurality of elongate legs to engage with an increasing diameter of the axial leg tracks, which thereby causes the first and second elongate legs to be elastically biased in a radially outward direction, and wherein the advancing of the piston and the hub member causes the piercing end of the administration member to pierce the fluid seal of the BFS bottle.