mhurhangee/ep-ind-claims huggingface dataset:
A method for the production of aspartate derived amino acids using Corynebacterium glutamicum comprising at least the following properties, compared with the initial Corynebacterium glutamicum: (a) increased glucose 6-phosphate dehydrogenase activity, wherein the increased glucose-6-phosphate dehydrogenase activity is due to (i) overexpression of the zwf -gene based on the replacement of the natural promoter of the zwf -gene through a heterologous promoter and/or (ii) amino acid residue exchange A243T (zwf), or (iii) through the replacement of the natural promoter of the tkt -operon through a heterologous promoter, (b) increased activity of fructose 1,6-bisphosphatase, wherein the increased activity of fructose 1,6-bisphosphatase is due to overexpression of the fbp -gene, based on the replacement of the natural promoter through a heterologous promoter, (c) attenuated isocitrate dehydrogenase activity, wherein the decreased activity is based on the replacement of the natural start codon of the icd, gene through a different start codon, (d) increased diaminopimelate dehydrogenase activity, wherein the increased diaminopimelate dehydrogenase activity is based on an overexpression of the ddh -gene, wherein the overexpression is based on gene-multiplication, and (e) increased aspartate kinase activity, wherein the increased aspartate kinase activity is based on an overexpression of the lysC -gene, wherein the overexpression is due to a modification of the lysC -gene resulting in the amino acid exchange T311I. (a) increased glucose 6-phosphate dehydrogenase activity, wherein the increased glucose-6-phosphate dehydrogenase activity is due to (i) overexpression of the zwf -gene based on the replacement of the natural promoter of the zwf -gene through a heterologous promoter and/or (ii) amino acid residue exchange A243T (zwf), or (iii) through the replacement of the natural promoter of the tkt -operon through a heterologous promoter, (b) increased activity of fructose 1,6-bisphosphatase, wherein the increased activity of fructose 1,6-bisphosphatase is due to overexpression of the fbp -gene, based on the replacement of the natural promoter through a heterologous promoter, (c) attenuated isocitrate dehydrogenase activity, wherein the decreased activity is based on the replacement of the natural start codon of the icd, gene through a different start codon, (d) increased diaminopimelate dehydrogenase activity, wherein the increased diaminopimelate dehydrogenase activity is based on an overexpression of the ddh -gene, wherein the overexpression is based on gene-multiplication, and (e) increased aspartate kinase activity, wherein the increased aspartate kinase activity is based on an overexpression of the lysC -gene, wherein the overexpression is due to a modification of the lysC -gene resulting in the amino acid exchange T311I.
A system, comprising: a personal electronic device comprising an attachment element defining an opening; and a flexible member including a first magnetic feature arranged on an end of the flexible member wherein: the flexible member extends through the opening and loops around a portion of the attachment element; and the first magnetic feature couples the end of the flexible member to a surface of the flexible member; a second magnetic feature is included in the flexible member, wherein the first magnetic feature is attachable to the second magnetic feature in a plurality of positions, wherein each of the first magnetic feature and the second magnetic member are fixed to the flexible member, and wherein the second magnetic feature is larger than the first magnetic feature. a personal electronic device comprising an attachment element defining an opening; and a flexible member including a first magnetic feature arranged on an end of the flexible member wherein: the flexible member extends through the opening and loops around a portion of the attachment element; and the first magnetic feature couples the end of the flexible member to a surface of the flexible member; the flexible member extends through the opening and loops around a portion of the attachment element; and the first magnetic feature couples the end of the flexible member to a surface of the flexible member; a second magnetic feature is included in the flexible member, wherein the first magnetic feature is attachable to the second magnetic feature in a plurality of positions, wherein each of the first magnetic feature and the second magnetic member are fixed to the flexible member, and wherein the second magnetic feature is larger than the first magnetic feature.
A benzobis(thiadiazole) derivative represented by the following general formula: wherein R 1 represents a linear or branched alkyl group, or any one of the groups of the following formula: wherein R represents a linear or branched alkyl group; R 2 represents a hydrogen atom; and R 3 represents a hydrogen atom, a linear or branched alkyl group, or any one of the groups of the formula; with the proviso that at least one of R 1 and R 3 represents any one of the groups of the formula; and two R 1 groups, two R 2 groups, and two R 3 groups may be the same as, or different from each other and the further proviso that a benzobis(thiadiazole) derivative of the general formula in which R 1 is -OCF 3, and R 2 and R 3 are hydrogen atoms is excluded. wherein R represents a linear or branched alkyl group; R 2 represents a hydrogen atom; and R 3 represents a hydrogen atom, a linear or branched alkyl group, or any one of the groups of the formula; with the proviso that at least one of R 1 and R 3 represents any one of the groups of the formula; and two R 1 groups, two R 2 groups, and two R 3 groups may be the same as, or different from each other and the further proviso that a benzobis(thiadiazole) derivative of the general formula in which R 1 is -OCF 3, and R 2 and R 3 are hydrogen atoms is excluded.
A neuromodulation apparatus comprising: a plurality of electrodes (2, 2a), each electrode of the plurality of electrodes having an electrically conductive element applicable to or under a skin of a patient; a pulse generator electrically connected to each electrode of the plurality of electrodes (2, 2a) for transmitting electric pulses to the plurality of electrodes; and a control unit coupled to the pulse generator and adapted to periodically measure a resistance and/or a current-voltage characteristic between at least two electrodes of the plurality of electrodes, wherein the control unit is adapted to control a shape of the electric pulses based on the measured resistance and/or current-voltage characteristic, wherein the control unit is configured to dynamically control an internal resistance of the pulse generator based on the periodical measurement of the resistance and/or the current-voltage characteristic. a plurality of electrodes (2, 2a), each electrode of the plurality of electrodes having an electrically conductive element applicable to or under a skin of a patient; a pulse generator electrically connected to each electrode of the plurality of electrodes (2, 2a) for transmitting electric pulses to the plurality of electrodes; and a control unit coupled to the pulse generator and adapted to periodically measure a resistance and/or a current-voltage characteristic between at least two electrodes of the plurality of electrodes, wherein the control unit is adapted to control a shape of the electric pulses based on the measured resistance and/or current-voltage characteristic, wherein the control unit is configured to dynamically control an internal resistance of the pulse generator based on the periodical measurement of the resistance and/or the current-voltage characteristic.
A standby power supply system for connection to a superordinate power supply grid and a local power distribution grid, comprising - a grid disconnection device for connecting the local power distribution grid to the superordinate power supply grid by at least two series-connected switching elements (111, 114), each comprising assigned switching contacts (113, 116), and - a local power supply device comprising an island detector for detecting an island situation of the local power distribution grid, characterized in that - a first of the two switching elements, for actuation thereof, is connected directly to the superordinate power supply grid, and - the second of the two switching elements, for actuation thereof, is connected to the local power supply device. - a grid disconnection device for connecting the local power distribution grid to the superordinate power supply grid by at least two series-connected switching elements (111, 114), each comprising assigned switching contacts (113, 116), and - a local power supply device comprising an island detector for detecting an island situation of the local power distribution grid, - a first of the two switching elements, for actuation thereof, is connected directly to the superordinate power supply grid, and - the second of the two switching elements, for actuation thereof, is connected to the local power supply device.
Monitoring system for monitoring a kinematic coupling between an actuator and a controlled element of an aircraft, wherein the monitoring system comprises: a first sensor, which is arranged such that it senses an operative movement of the actuator and, on the basis of the sensed operative movement of the actuator, provides a first signal; a second sensor, which is arranged such that it senses a movement of the controlled element and, on the basis of the sensed movement of the controlled element, provides a second signal; a computing unit, which is connected to the first sensor and the second sensor and is designed to receive the first signal and the second signal; wherein the computing unit is designed to determine, on the basis of the first signal, an anticipated movement of the controlled element and to compare the anticipated movement with the sensed movement corresponding to the second signal and to provide a deviation between the anticipated movement and the sensed movement; wherein the computing unit is designed to partially undertake a task which is usually carried out by a dedicated testing apparatus at predefined maintenance intervals on the ground, and to carry out this task during operation of the aircraft in the air; wherein the computing unit is designed to respond to a deviation between the anticipated movement and the sensed movement that exceeds a threshold value by outputting a warning of this deviation, causing the aircraft to be sent for detailed inspection. a first sensor, which is arranged such that it senses an operative movement of the actuator and, on the basis of the sensed operative movement of the actuator, provides a first signal; a second sensor, which is arranged such that it senses a movement of the controlled element and, on the basis of the sensed movement of the controlled element, provides a second signal; a computing unit, which is connected to the first sensor and the second sensor and is designed to receive the first signal and the second signal; wherein the computing unit is designed to determine, on the basis of the first signal, an anticipated movement of the controlled element and to compare the anticipated movement with the sensed movement corresponding to the second signal and to provide a deviation between the anticipated movement and the sensed movement; wherein the computing unit is designed to partially undertake a task which is usually carried out by a dedicated testing apparatus at predefined maintenance intervals on the ground, and to carry out this task during operation of the aircraft in the air; wherein the computing unit is designed to respond to a deviation between the anticipated movement and the sensed movement that exceeds a threshold value by outputting a warning of this deviation, causing the aircraft to be sent for detailed inspection.
A device for creating an aperture in an eye, comprising: a control unit for a laser unit, wherein the control unit is configured to control the laser unit to create the aperture in a lens of the eye, wherein the aperture is used to increase the depth of field of the eye and is formed by laser-induced lesions (5a, 5b, 10) which reduce light transmission through an aperture region of the lens surrounding an aperture opening, characterized in that the device further comprises an alignment unit for aligning and/or fixating the eye and a light stimulation unit for light stimulation of the eye in order to narrow the pupil, wherein the control unit is configured to control the laser unit on the basis of the narrowed pupil in orderto produce marks (12a, 12b) defining the aperture opening in the lateral and/or axial direction. a control unit for a laser unit, wherein the control unit is configured to control the laser unit to create the aperture in a lens of the eye, wherein the aperture is used to increase the depth of field of the eye and is formed by laser-induced lesions (5a, 5b, 10) which reduce light transmission through an aperture region of the lens surrounding an aperture opening, characterized in that the device further comprises an alignment unit for aligning and/or fixating the eye and a light stimulation unit for light stimulation of the eye in order to narrow the pupil, wherein the control unit is configured to control the laser unit on the basis of the narrowed pupil in orderto produce marks (12a, 12b) defining the aperture opening in the lateral and/or axial direction.
Device for being coupled to a space satellite (20', 20") before launch to remove said satellite from space or move said satellite in a different space orbit by remote control means or by said device, said device being independent with respect to said satellite and to said remote control means, said device comprising: - on-board control means of said device; - means for receiving control signals from said remote control means or means for emitting control signals to activate the moving/removing sequence, operatively connected with said on-board control means; - propulsion means operatively connected with said on-board control means, said propulsion means for generating a thrust and for being activated by said on-board control means upon receiving said control signals to remove said satellite (20', 20") from space in a predefined Earth area or move said satellite (20', 20") in a predefined different space orbit; - electric power supply means for said device, to make independent said device from said satellite; - pre-launch mechanical coupling means for coupling said device to said satellite (20', 20"); - means to mitigate misalignment of the thrust vector, operatively connected with said on-board control means; characterised in that said means to mitigate the misalignment comprises means for active control of the thrust vector which effect the alignment of said thrust vector; said means for active control of the thrust vector being configured for effecting an adjustable and/or a mobile connection between said satellite (20', 20") and said device to effect the alignment of said thrust vector. - on-board control means of said device; - means for receiving control signals from said remote control means or means for emitting control signals to activate the moving/removing sequence, operatively connected with said on-board control means; - propulsion means operatively connected with said on-board control means, said propulsion means for generating a thrust and for being activated by said on-board control means upon receiving said control signals to remove said satellite (20', 20") from space in a predefined Earth area or move said satellite (20', 20") in a predefined different space orbit; - electric power supply means for said device, to make independent said device from said satellite; - pre-launch mechanical coupling means for coupling said device to said satellite (20', 20"); - means to mitigate misalignment of the thrust vector, operatively connected with said on-board control means;
A portable device for detection of biomarkers in exhaled air, provided with a control module, interface system, a mouthpiece, a sensor unit and an air line, leading the air from mouthpiece through a sensor unit to an outlet port, wherein the air line includes a moisture filter and the sensor unit is configured for detection of biomarkers and is connected with a control module connected to an interface system, wherein the air line also includes a pre-concentrator and a carbon dioxide sensor connected with the control module, which is provided with a measurement triggering module configured to trigger a measurement executed with the sensor unit when the carbon dioxide sensor (CO 2) indication exceeds a threshold, the carbon dioxide sensor is located in the air line upstream of the sensor unit the device further has a second outlet port and a three-way valve located in the air line downstream of the carbon dioxide sensor, directing air to the second outlet port in its first position, a controlled valve cutting off air flow to the sensor unit, and to the pre-concentrator, the sensor unit and the first outlet port in its second position, wherein the pre-concentrator is integrated with the moisture filter in a single module including an air duct filled with absorbing and adsorbing compounds. to the second outlet port in its first position, a controlled valve cutting off air flow to the sensor unit, and to the pre-concentrator, the sensor unit and the first outlet port in its second position,
A multi-cavity oven comprising: a housing defining an interior cooking volume subdivided into multiple cooking cavities, the cooking volume surrounded by insulated outer walls (14a, 14b, 14c) and having at least one door that may open and close to provide access to the interior cooking volume; wherein each cavity provides a separate heater and a thermal sensor; and a controller configured to receive a user command to independently set the temperatures of different cooking cavities; humidity walls sized to extend the full lateral and front to back dimensions of the cooking volume, and including gaskets configured to seal moisture against passage between the cooking cavities, characterized in that the multi-cavity oven further comprises: at least one spray nozzle in each of the cooking cavities controlled by the controller to direct water at the walls (14a, 14b, 14c, 14d, 14e, 26) of the cooking cavities for cleaning the cooking cavities; and each of the cooking cavities is connected to a drain port providing a drain conduit leading to a common drain receptacle, wherein the common drain receptacle is positioned below the lowermost cooking cavity and is connected to each of the cooking cavities by separate connections. a housing defining an interior cooking volume subdivided into multiple cooking cavities, the cooking volume surrounded by insulated outer walls (14a, 14b, 14c) and having at least one door that may open and close to provide access to the interior cooking volume; wherein each cavity provides a separate heater and a thermal sensor; and a controller configured to receive a user command to independently set the temperatures of different cooking cavities; humidity walls sized to extend the full lateral and front to back dimensions of the cooking volume, and including gaskets configured to seal moisture against passage between the cooking cavities, characterized in that the multi-cavity oven further comprises: at least one spray nozzle in each of the cooking cavities controlled by the controller to direct water at the walls (14a, 14b, 14c, 14d, 14e, 26) of the cooking cavities for cleaning the cooking cavities; and each of the cooking cavities is connected to a drain port providing a drain conduit leading to a common drain receptacle, wherein the common drain receptacle is positioned below the lowermost cooking cavity and is connected to each of the cooking cavities by separate connections. at least one spray nozzle in each of the cooking cavities controlled by the controller to direct water at the walls (14a, 14b, 14c, 14d, 14e, 26) of the cooking cavities for cleaning the cooking cavities; and each of the cooking cavities is connected to a drain port providing a drain conduit leading to a common drain receptacle, wherein the common drain receptacle is positioned below the lowermost cooking cavity and is connected to each of the cooking cavities by separate connections.
A fastener (20, 500) for securing to a conveyor belt end (12, 14) having a cable (30, 504, 506), the fastener comprising: a crimp (52, 514, 516) configured to be fixed to the cable; a fastener body (40, 510) including a longitudinally extending upper plate portion (42, 530), a longitudinally extending lower plate portion (44, 532), and a loop portion (22, 534) connecting the upper and lower plate portions; apertures (64, 66, 78, 80, 564, 566, 568, 570) of the upper and lower plate portions; a stop body (54, 512, 901, 1001) configured to fit between the upper and lower plate portions of the fastener body and abut the crimp with the crimp longitudinally intermediate the stop body and the loop portion; and an attachment member (60, 62, 560, 562) configured to extend through the apertures of the upper and lower plate portions and clamp the upper and lower plate portions to the stop body so that the upper and lower plate portions resist movement of the stop body. a crimp (52, 514, 516) configured to be fixed to the cable; a fastener body (40, 510) including a longitudinally extending upper plate portion (42, 530), a longitudinally extending lower plate portion (44, 532), and a loop portion (22, 534) connecting the upper and lower plate portions; apertures (64, 66, 78, 80, 564, 566, 568, 570) of the upper and lower plate portions; a stop body (54, 512, 901, 1001) configured to fit between the upper and lower plate portions of the fastener body and abut the crimp with the crimp longitudinally intermediate the stop body and the loop portion; and an attachment member (60, 62, 560, 562) configured to extend through the apertures of the upper and lower plate portions and clamp the upper and lower plate portions to the stop body so that the upper and lower plate portions resist movement of the stop body.
A method of maintaining audio communication in a congested communication channel currently bearing the transmission of speech in the audio communication between a sender side and a receiver side, the communication channel comprising at least one signaling channel and at least one payload channel having a quality of service, comprising: monitoring the quality of service of the payload channel; interrupting the sending of speech from the sender side over the payload channel while retaining at least the signaling channel (33, 34) of the communication channel, if the quality of service of the payload channel is below a threshold; converting the speech at the respective sender side to text; and transmitting the text over the retained communication channel to the respective receiver side. monitoring the quality of service of the payload channel; interrupting the sending of speech from the sender side over the payload channel while retaining at least the signaling channel (33, 34) of the communication channel, if the quality of service of the payload channel is below a threshold; converting the speech at the respective sender side to text; and transmitting the text over the retained communication channel to the respective receiver side.