mhurhangee/ep-ind-claims huggingface dataset:
A mass analyser (130, 130', 130") for use in a mass spectrometer (100, 100', 100"), the mass analyser having: a set of electrodes including electrodes (L 1, L 2, L 3, L 4, S 1, S 2, S 3) arranged to form at least one electrostatic sector, the set of electrodes forming the at least one electrostatic sector being spatially arranged to be capable of providing an electrostatic field in a reference plane suitable for guiding ions along a 2D closed orbit in the reference plane, wherein the set of electrodes forming the at least one electrostatic sector extend along a drift path that is locally orthogonal to the reference plane, wherein the drift path curves around a reference axis included in the reference plane so that, in use, the set of electrodes provide a 3D electrostatic field region; wherein the mass analyser is configured so that, in use, the 3D electrostatic field region provided by the set of electrodes guides ions having different initial coordinates and velocities along a single predetermined 3D reference trajectory that curves around the reference axis. a set of electrodes including electrodes (L 1, L 2, L 3, L 4, S 1, S 2, S 3) arranged to form at least one electrostatic sector, the set of electrodes forming the at least one electrostatic sector being spatially arranged to be capable of providing an electrostatic field in a reference plane suitable for guiding ions along a 2D closed orbit in the reference plane, wherein the set of electrodes forming the at least one electrostatic sector extend along a drift path that is locally orthogonal to the reference plane, wherein the drift path curves around a reference axis included in the reference plane so that, in use, the set of electrodes provide a 3D electrostatic field region; wherein the mass analyser is configured so that, in use, the 3D electrostatic field region provided by the set of electrodes guides ions having different initial coordinates and velocities along a single predetermined 3D reference trajectory that curves around the reference axis.
Railway carriage for transporting passengers, comprising at least one passenger compartment and a heating system for the passenger compartment, the heating system comprising a source of infra-red radiation, at least one waveguide configured to guide the infra-red radiation generated by the source, and a diffuser configured to illuminate at least a portion of the passenger compartment with the infra-red radiation, characterised in that the source comprises a bar capable of emitting the infra-red radiation and a concentrator capable of concentrating the infra-red radiation and of injecting it into the waveguide.
A device for the edge trimming of a blank of a card-shaped identification, value or security document, wherein the blank comprises at least two parallel surfaces and a side edge connecting the two surfaces to one another, with a holding device for holding the blank in such a way that the blank remains free, at least in some areas, for the edge trimming, with a laser cutting device which is designed to emit a laser beam in such a way that it impinges in a focused manner on a predetermined cutting line of a trimming region of the blank, and with an inert gas device which is designed to supply at least one inert gas stream to the trimming region, wherein the inert gas device comprises a first supply channel for inert gas directed towards the one of the surfaces, the device being characterized in that the inert gas device comprises a second supply channel for inert gas directed towards the other of the surfaces. with a holding device for holding the blank in such a way that the blank remains free, at least in some areas, for the edge trimming, with a laser cutting device which is designed to emit a laser beam in such a way that it impinges in a focused manner on a predetermined cutting line of a trimming region of the blank, and with an inert gas device which is designed to supply at least one inert gas stream to the trimming region, wherein the inert gas device comprises a first supply channel for inert gas directed towards the one of the surfaces, the device being characterized in that the inert gas device comprises a second supply channel for inert gas directed towards the other of the surfaces.
An antibody that binds specifically to both PD1 and VEGFR2 or an antigen-binding portion of the antibody, wherein the antibody or antigen-binding portion comprises a heavy chain variable region and a light chain variable region, wherein (a) the VH region amino acid sequence comprises HCDR1 of GFTFSSYMMS (SEQ ID NO:1), HCDR2 of TISGGGSNKYYVDSVKG (SEQ ID NO: 42) and HCDR3 of QLYYFDY (SEQ ID NO:3); and the VL region amino acid sequence comprises LCDR1 of RASQESGIWLS (SEQ ID NO: 39), LCDR2 of TATSLAD (SEQ ID NO: 5) and LCDR3 of QQVSVTPFT (SEQ ID NO:11); (b) the VH region amino acid sequence comprises HCDR1 of GFTFSSYMMS (SEQ ID NO:1), HCDR2 of TISGGGSNKYYVDSVKG (SEQ ID NO: 42) and HCDR3 of QLYYFDY (SEQ ID NO:3); and the VL region amino acid sequence comprises LCDR1 of RASQESGIWLS (SEQ ID NO: 39), LCDR2 of AASSLQS (SEQ ID NO: 43) and LCDR3 of QQVSVTPFT (SEQ ID NO:11); (c) the VH region amino acid sequence comprises HCDR1 of GFTFSSYMMS (SEQ ID NO:1), HCDR2 of TISGGGSNKYYVDSVKG (SEQ ID NO: 42) and HCDR3 of QLYYFDY (SEQ ID NO:3); and the VL region amino acid sequence comprises LCDR1 of RASQESGIWLS (SEQ ID NO: 39), LCDR2 of TASSLAD (SEQ ID NO: 40) and LCDR3 of QQVSVTPFT (SEQ ID NO:11); or (d) the VH region amino acid sequence comprises HCDR1 of GFTFSSYMMS (SEQ ID NO:1), HCDR2 of TISGGGSNKYYVDSVKG (SEQ ID NO: 42) and HCDR3 of QLYYFDY (SEQ ID NO:3); and the VL region amino acid sequence comprises LCDR1 of RASQESGIWLS (SEQ ID NO: 39), LCDR2 of AASSLAD (SEQ ID NO: 41) and LCDR3 of QQVSVTPFT (SEQ ID NO:11). (a) the VH region amino acid sequence comprises HCDR1 of GFTFSSYMMS (SEQ ID NO:1), HCDR2 of TISGGGSNKYYVDSVKG (SEQ ID NO: 42) and HCDR3 of QLYYFDY (SEQ ID NO:3); and the VL region amino acid sequence comprises LCDR1 of RASQESGIWLS (SEQ ID NO: 39), LCDR2 of TATSLAD (SEQ ID NO: 5) and LCDR3 of QQVSVTPFT (SEQ ID NO:11); (b) the VH region amino acid sequence comprises HCDR1 of GFTFSSYMMS (SEQ ID NO:1), HCDR2 of TISGGGSNKYYVDSVKG (SEQ ID NO: 42) and HCDR3 of QLYYFDY (SEQ ID NO:3); and the VL region amino acid sequence comprises LCDR1 of RASQESGIWLS (SEQ ID NO: 39), LCDR2 of AASSLQS (SEQ ID NO: 43) and LCDR3 of QQVSVTPFT (SEQ ID NO:11); (c) the VH region amino acid sequence comprises HCDR1 of GFTFSSYMMS (SEQ ID NO:1), HCDR2 of TISGGGSNKYYVDSVKG (SEQ ID NO: 42) and HCDR3 of QLYYFDY (SEQ ID NO:3); and the VL region amino acid sequence comprises LCDR1 of RASQESGIWLS (SEQ ID NO: 39), LCDR2 of TASSLAD (SEQ ID NO: 40) and LCDR3 of QQVSVTPFT (SEQ ID NO:11); or (d) the VH region amino acid sequence comprises HCDR1 of GFTFSSYMMS (SEQ ID NO:1), HCDR2 of TISGGGSNKYYVDSVKG (SEQ ID NO: 42) and HCDR3 of QLYYFDY (SEQ ID NO:3); and the VL region amino acid sequence comprises LCDR1 of RASQESGIWLS (SEQ ID NO: 39), LCDR2 of AASSLAD (SEQ ID NO: 41) and LCDR3 of QQVSVTPFT (SEQ ID NO:11).
A compound of the formula: wherein: X 1, X 2, X 3, X 6, and X 7 are each independently hydrogen, halo, hydroxy, carboxy, ester (C≤12), substituted ester (C≤12), alkoxy (C≤12), or substituted alkoxy (C≤12); X 4 is acyl (C≤18) or substituted acyl (C≤18); X 5 is hydrogen, hydroxy, alkoxy (C≤12), or substituted alkoxy (C≤12); Y 1, Y 2, and Y 3 are each independently O, S, or NH; A is O or S; R 1, R 1 ', R 2, R 2 ', R 3, and R 3 ' are each independently hydrogen, amino, halo, hydroxy, mercapto, or alkyl (C≤8), alkoxy (C≤8), alkylthio (C≤8), alkylamino (C≤8), dialkylamino (C≤8), or a substituted version of any of these groups; Y 4 is arenediyl (C≤12), heteroarenediyl (C≤12), or a substituted version of either of these groups; each X 8 is independently -X 9 -heteroarenediyl (C≤12) or substituted -X 9 -heteroarenediyl (C≤12), wherein: X 9 is -NHC - or -C NH-; R 4 is hydrogen, amino, nitro, alkylamino (C≤12), dialkylamino (C≤12), amido (C≤12), substituted alkylamino (C≤12), substituted dialkylamino (C≤12), or substituted amido (C≤12); m is 0, 1, 2, or 3; and n is 1, 2, or 3; or a pharmaceutically acceptable salt thereof; and when a term is used with the "substituted" modifier one or more hydrogen atom has been independently replaced by -OH, -F, -Cl, -Br, -I, -NH 2, -NO 2, -CO 2 H, -CO 2 CH 3, -CN, -SH, -OCH 3, -OCH 2 CH 3, -C CH 3, -NHCH 3, -NHCH 2 CH 3, -N(CH 3) 2, -C NH 2, -C NHCH 3, -C N(CH 3) 2, -OC CH 3, -NHC CH 3, -S 2 OH, or -S 2 NH 2. X 1, X 2, X 3, X 6, and X 7 are each independently hydrogen, halo, hydroxy, carboxy, ester (C≤12), substituted ester (C≤12), alkoxy (C≤12), or substituted alkoxy (C≤12); X 4 is acyl (C≤18) or substituted acyl (C≤18); X 5 is hydrogen, hydroxy, alkoxy (C≤12), or substituted alkoxy (C≤12); Y 1, Y 2, and Y 3 are each independently O, S, or NH; A is O or S; R 1, R 1 ', R 2, R 2 ', R 3, and R 3 ' are each independently hydrogen, amino, halo, hydroxy, mercapto, or alkyl (C≤8), alkoxy (C≤8), alkylthio (C≤8), alkylamino (C≤8), dialkylamino (C≤8), or a substituted version of any of these groups; Y 4 is arenediyl (C≤12), heteroarenediyl (C≤12), or a substituted version of either of these groups; each X 8 is independently -X 9 -heteroarenediyl (C≤12) or substituted -X 9 -heteroarenediyl (C≤12), wherein: X 9 is -NHC - or -C NH-; R 4 is hydrogen, amino, nitro, alkylamino (C≤12), dialkylamino (C≤12), amido (C≤12), substituted alkylamino (C≤12), substituted dialkylamino (C≤12), or substituted amido (C≤12); m is 0, 1, 2, or 3; and n is 1, 2, or 3;
A drug combination against acid-fast bacillus, comprising: an inhibitor for WecA or an ortholog thereof; and an inhibitor for MurX or an ortholog thereof; and, optionally, an RNA synthesis inhibitor, wherein the inhibitor for WecA or an ortholog thereof is used in combination with the inhibitor for MurX or an ortholog thereof and, optionally, the RNA synthesis inhibitor; wherein the inhibitor for WecA or an ortholog thereof contains a compound expressed by the following Structural Formula, and the inhibitor for MurX or an ortholog thereof contains a compound expressed by the following Structural Formula: wherein in Structural Formula, "Me" is a methyl group. an inhibitor for WecA or an ortholog thereof; and an inhibitor for MurX or an ortholog thereof; and, optionally, an RNA synthesis inhibitor,
A method for monitoring of an individual when installing an equipment, comprising: monitoring through a motion sensing input device an individual installing equipment, which involves the positions of kneeling, standing or reaching, wherein the motion sensing input device comprises a motion sensor; collecting, at a computer, motion sensor input data of motions of the individual from the motion sensor for an interval of time, for use in determining qualitative description of positions of the individual, wherein said motion sensor is placed in a position where it can remotely observe the individual's movements; analyzing, using the computer, the motion sensor input data using an analysis application having a set of classified predetermined motions of interest to classify and identify a position of the individual using an associative memory classification as one of at least standing, reaching or kneeling, wherein the analysis application classifies a movement captured during the interval of time as a motion corresponding to one of the set of classified predetermined motions of interest based on shared relative attributes; generating an output providing notice of the identified predetermined motion of interest to a monitoring system; and responsive to receiving the notice, collecting metrics on the motion of interest, said metrics including a duration the individual maintains a potentially risky position during said motion of interest, wherein said risky position is a position that can cause harm to said individual if done repeatedly or incorrectly. monitoring through a motion sensing input device an individual installing equipment, which involves the positions of kneeling, standing or reaching, wherein the motion sensing input device comprises a motion sensor; collecting, at a computer, motion sensor input data of motions of the individual from the motion sensor for an interval of time, for use in determining qualitative description of positions of the individual, wherein said motion sensor is placed in a position where it can remotely observe the individual's movements; analyzing, using the computer, the motion sensor input data using an analysis application having a set of classified predetermined motions of interest to classify and identify a position of the individual using an associative memory classification as one of at least standing, reaching or kneeling, wherein the analysis application classifies a movement captured during the interval of time as a motion corresponding to one of the set of classified predetermined motions of interest based on shared relative attributes; generating an output providing notice of the identified predetermined motion of interest to a monitoring system; and responsive to receiving the notice, collecting metrics on the motion of interest, said metrics including a duration the individual maintains a potentially risky position during said motion of interest, wherein said risky position is a position that can cause harm to said individual if done repeatedly or incorrectly.
A method, comprising: coordinating, by a first base station, with a second neighboring base station to assign uplink resources to a first mobile device in an uplink coordinated multi-point environment, the uplink resources corresponding to a node from a hopping tree; signaling information that identifies the uplink resources to the first mobile device; receiving the uplink signal from the first mobile device upon the uplink resources; and transmitting an acknowledgment to the first mobile device via downlink resources selected based at least in part on the hopping tree, the node allotted for the uplink signal, and the uplink resources corresponding to the node from the hopping tree. coordinating, by a first base station, with a second neighboring base station to assign uplink resources to a first mobile device in an uplink coordinated multi-point environment, the uplink resources corresponding to a node from a hopping tree; signaling information that identifies the uplink resources to the first mobile device; receiving the uplink signal from the first mobile device upon the uplink resources; and transmitting an acknowledgment to the first mobile device via downlink resources selected based at least in part on the hopping tree, the node allotted for the uplink signal, and the uplink resources corresponding to the node from the hopping tree.
A process for obtaining a 3D reduced graphene oxide/Fe 2 O 3 material comprising a 3D reduced graphene oxide matrix and grafted Fe 2 O 3 nanoparticles randomly distributed within the 3D reduced graphene oxide matrix, further comprising a 3D structure with open pores with presence of macropores (> 50 nm), mesopores (between 2 and 50 nm) and micropores (< 2 nm) wherein the average nanoparticle diameter is between 20 nm and 100 nm, and the micropore volume calculated by the t-plot method is between 0.00574 cm 3 /g and 0.0146 cm 3 /g, which comprises the following steps: (i) putting in contact a graphene oxide water dispersion with an aqueous solution of iron sulfate, (ii) hydrothermal treatment of the resulting dispersion from previous step (i), (iii) freezing the reaction product obtained in step (ii) at a temperature ≤ -5 °C; and (iv) lyophilisation of the product obtained in step (iii). (i) putting in contact a graphene oxide water dispersion with an aqueous solution of iron sulfate, (ii) hydrothermal treatment of the resulting dispersion from previous step (i), (iii) freezing the reaction product obtained in step (ii) at a temperature ≤ -5 °C; and (iv) lyophilisation of the product obtained in step (iii).
A device for the safe storage of flammable materials, in particular lithium-ion accumulators, comprising • a lower container, which is refractory and has an opening at the top side, • an upper container, which preferably comprises solid, free-flowing extinguishing agent, and has an opening at the bottom side, • and a release device with a fuse, wherein the upper container is detachably attachable above the lower container, characterized in that the release device provides a releasable connection between the upper container and the lower container in the area of the respective opening (1', 2'), wherein the releasable connection closes the opening at the top side of the lower container and the opening at the bottom side of the upper container and wherein the fuse, after being triggered by a trigger temperature, opens the opening at the bottom side of the upper container and the opening at the top side of the lower container and establishes a material-conducting connection. • a lower container, which is refractory and has an opening at the top side, • an upper container, which preferably comprises solid, free-flowing extinguishing agent, and has an opening at the bottom side, • and a release device with a fuse, wherein the upper container is detachably attachable above the lower container, characterized in that the release device provides a releasable connection between the upper container and the lower container in the area of the respective opening (1', 2'), wherein the releasable connection closes the opening at the top side of the lower container and the opening at the bottom side of the upper container and wherein the fuse, after being triggered by a trigger temperature, opens the opening at the bottom side of the upper container and the opening at the top side of the lower container and establishes a material-conducting connection.
A dual riser fluid catalytic cracking process, comprising: cracking a hydrocarbon feed in a first riser comprising a first catalyst under first riser conditions to form a first effluent enriched in olefins, light gasoil, gasoline, or a combination thereof; cracking a hydrocarbon oxygenate feed in a second riser comprising a second catalyst under second riser conditions to form a second effluent enriched in olefins; recovering the first and second catalyst from the first and second effluents in a common reactor; regenerating the recovered first and second catalyst in a regenerator using heat from the exothermic cracking of the hydrocarbon oxygenate feed; and recirculating the regenerated first and second catalyst to the first and second riser; wherein the first catalyst and the second catalysts have different densities such that they form a layer of first catalyst and a layer of second catalyst in the regenerator; wherein recirculating the regenerated first and second catalyst to the first and second riser further comprises positioning a first riser standpipe to recirculate regenerated first catalyst to the first riser from the layer of first catalyst; and positioning a second riser standpipe to recirculate a regenerated second catalyst to the second riser from the layer of second catalyst. cracking a hydrocarbon feed in a first riser comprising a first catalyst under first riser conditions to form a first effluent enriched in olefins, light gasoil, gasoline, or a combination thereof; cracking a hydrocarbon oxygenate feed in a second riser comprising a second catalyst under second riser conditions to form a second effluent enriched in olefins; recovering the first and second catalyst from the first and second effluents in a common reactor; regenerating the recovered first and second catalyst in a regenerator using heat from the exothermic cracking of the hydrocarbon oxygenate feed; and recirculating the regenerated first and second catalyst to the first and second riser; wherein the first catalyst and the second catalysts have different densities such that they form a layer of first catalyst and a layer of second catalyst in the regenerator; wherein recirculating the regenerated first and second catalyst to the first and second riser further comprises positioning a first riser standpipe to recirculate regenerated first catalyst to the first riser from the layer of first catalyst; and positioning a second riser standpipe to recirculate a regenerated second catalyst to the second riser from the layer of second catalyst.
A process to manage water heating in a tank of a water heater which includes a device for electrically heating the water in the tank and a heating management device configured to control the activation and deactivation of the heating device, said heating management device including at least one temperature measuring sensor capable of measuring a temperature in the tank and means arranged to execute said process, said process includes, when a water heating phase is controlled: - an activation of heating by the heating device at a first heating power; - a determination of a time variation of temperature in the tank by said at least one temperature measuring sensor; - a determination of at least one water filling state of the tank as a function of the time variation; and during the heating phase, one performs: - a periodic determination of a time variation of temperature in the tank by said at least one temperature measuring sensor during a predefined time interval; - a determination by said arranged means of an insufficient water filling state of the tank when a positive time variation which is greater than a predefined value is identified; - a stop of heating following the determination of the insufficient filling state; - a determination by said arranged means of a sufficient filling state when a positive time variation which is less than a predefined value is identified; - a heating phase at a heating power which is greater than the first heating power, this heating phase at a higher power being controlled upon determination of the sufficient filling state. - an activation of heating by the heating device at a first heating power; - a determination of a time variation of temperature in the tank by said at least one temperature measuring sensor; - a determination of at least one water filling state of the tank as a function of the time variation; - a periodic determination of a time variation of temperature in the tank by said at least one temperature measuring sensor during a predefined time interval; - a determination by said arranged means of an insufficient water filling state of the tank when a positive time variation which is greater than a predefined value is identified; - a stop of heating following the determination of the insufficient filling state; - a determination by said arranged means of a sufficient filling state when a positive time variation which is less than a predefined value is identified; - a heating phase at a heating power which is greater than the first heating power, this heating phase at a higher power being controlled upon determination of the sufficient filling state.