mhurhangee/ep-ind-claims huggingface dataset:
A flu polypeptide comprising an isolated immunogenic core polypeptide capable of generating an immune response that is cross-reactive with a plurality of influenza virus strains from different subtypes, wherein the isolated immunogenic core polypeptide is linked to a carrier protein and wherein the isolated immunogenic core polypeptide comprises the formula: wherein the isolated immunogenic core polypeptide is less than 75 amino acids in length, and wherein (a) the flu polypeptide is acetylated at its N-terminus; (b) the flu polypeptide is linked to polyethylene glycol at its N- and/or C-terminus; (c) the core polypeptide is directly or indirectly linked at its N- and/or C- terminus to one or more protein tags, preferably the protein tag is a His-tag or a FLAG-tag; (d) the core polypeptide is directly or indirectly linked at its N- and/or C- terminus to a T-cell epitope, preferably a CD8 T-cell epitope, preferably the CD8 T-cell epitope is influenza A nuclear protein or matrix 1 protein or fragment thereof; (e) the core polypeptide is directly or indirectly linked at its N- and/or C- terminus to a Toll Like Receptor ligand, preferably the Toll Like Receptor ligand is Salmonella flagellin; (f) the core polypeptide is directly or indirectly linked at its N- and/or C- terminus to a T4 foldon domain or a fragment thereof; (g) the core polypeptide is linked at its N-terminus to a His-tag and linked at its C-terminus to a T4 foldon domain or fragment thereof; or (h) the core polypeptide is linked at its C-terminus to a polypeptide having the sequence DYKDDDKC. (a) the flu polypeptide is acetylated at its N-terminus; (b) the flu polypeptide is linked to polyethylene glycol at its N- and/or C-terminus; (c) the core polypeptide is directly or indirectly linked at its N- and/or C- terminus to one or more protein tags, preferably the protein tag is a His-tag or a FLAG-tag; (d) the core polypeptide is directly or indirectly linked at its N- and/or C- terminus to a T-cell epitope, preferably a CD8 T-cell epitope, preferably the CD8 T-cell epitope is influenza A nuclear protein or matrix 1 protein or fragment thereof; (e) the core polypeptide is directly or indirectly linked at its N- and/or C- terminus to a Toll Like Receptor ligand, preferably the Toll Like Receptor ligand is Salmonella flagellin; (f) the core polypeptide is directly or indirectly linked at its N- and/or C- terminus to a T4 foldon domain or a fragment thereof; (g) the core polypeptide is linked at its N-terminus to a His-tag and linked at its C-terminus to a T4 foldon domain or fragment thereof; or (h) the core polypeptide is linked at its C-terminus to a polypeptide having the sequence DYKDDDKC.
A system for outputting an altered audio signal, the system comprising: - means for providing a noise reducing signal, - means for providing or receiving an audio signal, - means (18, 20, 22, 24) for outputting an altered audio signal based on the audio signal and the noise reducing signal, and means for limiting the altered audio signal; whereby the outputting means (18, 20, 22, 24) is adapted to o limit the noise reducing signal and the audio signal, o provide the altered audio signal by combining: • the limited audio signal with the limited noise reducing signal, wherein the outputting means (18, 20, 22, 24) are adapted to: - limit the audio signal so as to have a level/strength no higher than a first predetermined level/strength and the system characterized in that the outputting means is adapted to - limit the noise reducing signal so that the combined, limited audio signal and noise reducing signal have a level/strength no higher than a second, predetermined level/strength, wherein the first predetermined level/strength is lower than the second predetermined level/strength. - means for providing a noise reducing signal, - means for providing or receiving an audio signal, - means (18, 20, 22, 24) for outputting an altered audio signal based on the audio signal and the noise reducing signal, and means for limiting the altered audio signal; o limit the noise reducing signal and the audio signal, o provide the altered audio signal by combining: • the limited audio signal with the limited noise reducing signal, wherein the outputting means (18, 20, 22, 24) are adapted to: - limit the audio signal so as to have a level/strength no higher than a first predetermined level/strength and the system characterized in that the outputting means is adapted to - limit the noise reducing signal so that the combined, limited audio signal and noise reducing signal have a level/strength no higher than a second, predetermined level/strength, • the limited audio signal with the limited noise reducing signal, wherein the outputting means (18, 20, 22, 24) are adapted to: - limit the audio signal so as to have a level/strength no higher than a first predetermined level/strength and the system characterized in that the outputting means is adapted to - limit the noise reducing signal so that the combined, limited audio signal and noise reducing signal have a level/strength no higher than a second, predetermined level/strength, - limit the audio signal so as to have a level/strength no higher than a first predetermined level/strength and the system characterized in that the outputting means is adapted to - limit the noise reducing signal so that the combined, limited audio signal and noise reducing signal have a level/strength no higher than a second, predetermined level/strength,
Method for operating a panel dividing system, in which a panel-like workpiece is held at least temporarily by clamping by means of at least one clamping device and is divided in the clamped state, said method comprising at least the following steps: a. holding the plate-like workpiece on a workpiece edge which is at the rear when viewed in a feed direction by means of a plurality of clamping devices (24a-f) of a feed device, and then carrying out a first dividing process such that a separated workpiece and a remaining workpiece that is still clamped are formed; b. releasing the clamping of the remaining workpiece at least in regions by at least one of the clamping devices (24a-b, 24d-f) being opened such that the remaining workpiece can deform due to internal stresses; c. positioning the remaining workpiece for a second dividing process by means of the feed device; d. carrying out the second dividing process, characterized in that, in step b, at least initially a first portion of the rear workpiece edge continues to be clamped and held by at least one clamping device, whereas a second portion of the rear workpiece edge of the remaining workpiece comes free from at least one clamping device (24a-b, 24d-f). a. holding the plate-like workpiece on a workpiece edge which is at the rear when viewed in a feed direction by means of a plurality of clamping devices (24a-f) of a feed device, and then carrying out a first dividing process such that a separated workpiece and a remaining workpiece that is still clamped are formed; b. releasing the clamping of the remaining workpiece at least in regions by at least one of the clamping devices (24a-b, 24d-f) being opened such that the remaining workpiece can deform due to internal stresses; c. positioning the remaining workpiece for a second dividing process by means of the feed device; d. carrying out the second dividing process, characterized in that, in step b, at least initially a first portion of the rear workpiece edge continues to be clamped and held by at least one clamping device, whereas a second portion of the rear workpiece edge of the remaining workpiece comes free from at least one clamping device (24a-b, 24d-f).
Process for producing at least one sintered ceramic part, wherein before sintering a ceramic part is present in an open-pored brown body state, and is provided at least in regions of its surface with an additive in the form of a solution comprising a solvent as carrier substance and a solid in the form of a metal salt dissolved therein as additional material, and is subsequently sintered, characterized in that the additional material is reduced before and/or during sintering.
An extractor (20, 220, 320, 420, 520, 620, 720) comprising: a housing; a suction source (29, 529, 629) disposed within the housing; a suction nozzle (34, 534, 634, 734) in communication with the suction source and movable relative to the housing; a recovery tank (26, 626, 726) carried by the housing, wherein the suction source is in communication with the recovery tank for drawing fluid through the suction nozzle and storing the drawn fluid in the recovery tank; and a cleaning chamber (68, 268, 368, 468, 568, 668, 768) with the housing for receiving at least a portion of the suction nozzle, wherein the cleaning chamber is configured to selectively receive a cleaning fluid along a fluid flow path (70, 470, 570, 670) in communication with the cleaning chamber, wherein the suction source is in communication with the cleaning chamber and configured to draw the cleaning fluid through the fluid flow path (66, 566, 70, 470, 570, 670) to the recovery tank when the portion of the suction nozzle is received in the cleaning chamber. a housing; a suction source (29, 529, 629) disposed within the housing; a suction nozzle (34, 534, 634, 734) in communication with the suction source and movable relative to the housing; a recovery tank (26, 626, 726) carried by the housing, wherein the suction source is in communication with the recovery tank for drawing fluid through the suction nozzle and storing the drawn fluid in the recovery tank; and a cleaning chamber (68, 268, 368, 468, 568, 668, 768) with the housing for receiving at least a portion of the suction nozzle, wherein the cleaning chamber is configured to selectively receive a cleaning fluid along a fluid flow path (70, 470, 570, 670) in communication with the cleaning chamber, wherein the suction source is in communication with the cleaning chamber and configured to draw the cleaning fluid through the fluid flow path (66, 566, 70, 470, 570, 670) to the recovery tank when the portion of the suction nozzle is received in the cleaning chamber.
A steering wheel cover with a multilayer structure which in the unwound state has a circumferential length and a cross-sectional width and whose layers cover each other at least partially in projection, with a lower electrically conductive shielding layer and with an upper cover layer, between which are arranged, starting from the shielding layer, an insulation layer and at least one electrically conductive sensor layer, wherein at least one of the shielding layer and the sensor layer comprises a conductor structure with conductors extending in circumferential length and cross-sectional width, and wherein the shielding layer and the sensor layer are electrically connected to connecting conductors of a connecting cable, characterized in that the electrical connection of the respective connecting conductors of the connecting cable with at least one of the shielding layer and the sensor layer is formed by a respective metal foil.
Method of colouring or lightening of human keratin fibres in the presence of an oxidizing agent, in which the following are applied on said fibres: (a) an anhydrous cosmetic composition comprising one or more fats and one or more surfactants; (b) a composition comprising one or more oxidizing agents; (c) a composition comprising one or more inorganic bases having the following structure: (Z 1 x-) m (Z 2 y+) n in which Z 2 denotes a metal from columns 1 to 13, preferably from columns 1 and 2, of the periodic table of the elements Z 1 x- denotes an anion selected from the ions CO 3 2-, OH -, HCO 3 2-, SiO 3 2-, HPO 4 2-, PO 4 3-, B 4 O 7 2-, preferably selected from the ions CO 3 2-, OH -, SiO 3 2- x denotes 1, 2 or 3 y denotes 1, 2, 3 or 4 m and n denote independently of one another 1, 2, 3 or 4 with n.y=m.x; the final composition resulting from mixing compositions, and; mixing being carried out either before application on the keratin fibres (extemporaneous preparation) or directly on the keratin fibres (successive applications with or without premixing and without intermediate rinsing). (a) an anhydrous cosmetic composition comprising one or more fats and one or more surfactants; (b) a composition comprising one or more oxidizing agents; (c) a composition comprising one or more inorganic bases having the following structure: (Z 1 x-) m (Z 2 y+) n in which Z 2 denotes a metal from columns 1 to 13, preferably from columns 1 and 2, of the periodic table of the elements Z 1 x- denotes an anion selected from the ions CO 3 2-, OH -, HCO 3 2-, SiO 3 2-, HPO 4 2-, PO 4 3-, B 4 O 7 2-, preferably selected from the ions CO 3 2-, OH -, SiO 3 2- x denotes 1, 2 or 3 y denotes 1, 2, 3 or 4 m and n denote independently of one another 1, 2, 3 or 4 with n.y=m.x; the final composition resulting from mixing compositions, and; mixing being carried out either before application on the keratin fibres (extemporaneous preparation) or directly on the keratin fibres (successive applications with or without premixing and without intermediate rinsing). Z 2 denotes a metal from columns 1 to 13, preferably from columns 1 and 2, of the periodic table of the elements Z 1 x- denotes an anion selected from the ions CO 3 2-, OH -, HCO 3 2-, SiO 3 2-, HPO 4 2-, PO 4 3-, B 4 O 7 2-, preferably selected from the ions CO 3 2-, OH -, SiO 3 2- x denotes 1, 2 or 3 y denotes 1, 2, 3 or 4 m and n denote independently of one another 1, 2, 3 or 4 with n.y=m.x;
A coated cutting tool comprising a substrate and a coating, where the coating comprises at least one compound layer of Ti 1-x Al x N, in which 0.5<x<0.7 or 0.3<x<0.5, which is deposited by cathodic arc deposition, and which has a thickness of more than 15 μm to 30 μm, characterized in that the coating has internal compressive stresses in the range of higher than 1.3 GPa to 2 GPa as determined by X-ray diffraction analysis using the sin 2 Ψ method.
A grommet of non-through type adapted to being attached to a grommet accommodating concave portion formed on a door panel of a vehicle, the grommet comprising: a protector that accommodates a wire harness; and a grommet base portion that has a protector accommodating portion which accommodates the protector, wherein the grommet base portion includes: a clamp insertion opening provided on a back side of the grommet base portion; a first water stop lip protrudently formed around the clamp insertion opening; and a second water stop lip provided in a position closer to an inside of a vehicle cabin than the first water stop lip when the grommet is attached to the grommet accommodating concave portion, the second water stop lip being formed so as to extend substantially in a vertical direction of the vehicle when the grommet is attached to the grommet accomodating concave portion; and wherein the protector has a clamp adapted to being engaged with the door panel on a bottom surface, and the clamp protrudes from the clamp insertion opening so that the clamp can be locked on the door panel. a protector that accommodates a wire harness; and a grommet base portion that has a protector accommodating portion which accommodates the protector, a clamp insertion opening provided on a back side of the grommet base portion; a first water stop lip protrudently formed around the clamp insertion opening; and a second water stop lip provided in a position closer to an inside of a vehicle cabin than the first water stop lip when the grommet is attached to the grommet accommodating concave portion, the second water stop lip being formed so as to extend substantially in a vertical direction of the vehicle when the grommet is attached to the grommet accomodating concave portion; and
Diffuser for an inflator, in particular for an inflator of an airbag system, with a housing in which radial outflow openings are formed, wherein a plurality of outflow segments (14, 15, 16, 17) are provided which are adjacent to one another in the longitudinal axial direction, each of which has a number of outflow openings spaced apart in the circumferential direction, and with a combustion-gas filtering element which is arranged within the housing in the region of the outflow segments (14, 15, 16, 17), wherein the filtering element has different wall thicknesses in regions of at least two outflow segments (14, 15, 16, 17) adjacent to one another, characterized in that the filtering element has an inlet portion at a proximal longitudinal end which comprises a longitudinal axial gas inlet opening and a reduction portion, which is arranged downstream of the proximal inlet portion in the direction of the gas flow, wherein the wall thickness of the filtering element increases continuously in the reduction portion, and the filtering element comprises a collection portion which is arranged downstream of the reduction portion in the direction of the gas flow, wherein the filtering element has a constant wall thickness in the collection portion.
A structure for a front portion of an automobile body, comprising a front side frame that extends in a fore-and-aft direction, a vertical member (24, 32) that is joined to a front portion of the front side frame and extends in a vertical direction, a wheel house upper member that extends downwardly and toward the front from a front end of a front pillar outside the front side frame in the vehicle width direction, a side frame gusset that provides a connection between a front portion of the front side frame and a front portion of the wheel house upper member, and a linking panel that joins the vertical member (24, 32) and the side frame gusset within a plane T, being a plane perpendicular to an axis in the fore-and-aft direction, wherein a front bulkhead formed into a frame shape is disposed between front portions of a pair of left and right front side frames, characterized in that the front bulkhead is fixed to the front side frame via a reinforcing member, and the reinforcing member comprises a side wall portion that provides a connection as a continuous face between an outer face in the vehicle width direction of the front bulkhead and an outer face in the vehicle width direction of the front side frame.
A motorcycle comprising: a vehicle body frame including a head pipe, a pair of right and left main frames extending rearward from the head pipe, and a pair of right and left pivot frames which extend continuously from rear portions of the main frames, respectively, and to which a front end portion of a swing arm is mounted such that the swing arm is pivotable; and a brake control unit; characterized in that the motorcycle further comprises a reservoir tank including a container body which stores therein a cooling medium supplied to a radiator and has a cooling medium port, and a cap which closes the cooling medium port of the container body, wherein the brake control unit and the reservoir tank are disposed inward relative to the pivot frames, and mounted to the vehicle body frame via a common bracket. a vehicle body frame including a head pipe, a pair of right and left main frames extending rearward from the head pipe, and a pair of right and left pivot frames which extend continuously from rear portions of the main frames, respectively, and to which a front end portion of a swing arm is mounted such that the swing arm is pivotable; and a brake control unit; characterized in that the motorcycle further comprises a reservoir tank including a container body which stores therein a cooling medium supplied to a radiator and has a cooling medium port, and a cap which closes the cooling medium port of the container body, wherein the brake control unit and the reservoir tank are disposed inward relative to the pivot frames, and mounted to the vehicle body frame via a common bracket.
Rotary drilling tool for producing a bore in the ground, having - a base body and - a discharge line for discharging removed ground material and drilling suspension, - wherein a pumping device is provided and - wherein a pumping device is configured for pumping off the removed ground material with drilling suspension through the discharge line, characterized in that - the pumping device is arranged on the base body along the discharge line, - in that there is provided a removal device arranged on an underside of the base body, which removal device comprises a plurality of hammer units which each comprise a hammer element driven in axially reversing manner, - in that the hammer elements each comprise a vertically oriented piston which is in each case displaceably mounted in a cylinder housing of the hammer unit, and - in that on the underside of base body is arranged a plurality of extraction openings for extracting of the removed ground material. - a base body and - a discharge line for discharging removed ground material and drilling suspension, - wherein a pumping device is provided and - wherein a pumping device is configured for pumping off the removed ground material with drilling suspension through the discharge line, - the pumping device is arranged on the base body along the discharge line, - in that there is provided a removal device arranged on an underside of the base body, which removal device comprises a plurality of hammer units which each comprise a hammer element driven in axially reversing manner, - in that the hammer elements each comprise a vertically oriented piston which is in each case displaceably mounted in a cylinder housing of the hammer unit, and - in that on the underside of base body is arranged a plurality of extraction openings for extracting of the removed ground material.
A thermosetting resin composition comprising a melamine-based resin and one or more modifiers, characterized in that the total content of said modifiers is below 10%, preferably below 7%, more preferably below 5%, even more preferably below 3% by weight of the thermosetting resin, characterized in that the melamine-based resin comprises a mixture of at least melamine formaldehyde resin and etherified melamine resin and in that the ratio between the melamine formaldehyde resin and the etherified melamine resin is comprised between 10:90 and 90:10, preferably between 30:70 and 70:30 for example 50:50.
A guide for planning and drilling the subsequent placement of dental implants, comprising: - A support; - A plate fastened on the support such that the plate can be moved and detached with respect to the support; - A rod comprising an upper end that is rotatably joined to the support that enable the relative movement between them, and a lower end that is insertable in the bone tissue of the mouth of the patient, wherein the plate comprises: - a guide body located at one of its free end; and - horizontal movement means formed by an elongated opening extending between the free end where the guide body is located and the free end opposite to the guided body, such that the assembly formed by the support and the rod can move along the opening in order to be able to vary the distance between the rod and the guide body, wherein the guided body is made up of a cylindrical body that has a wide radial slot facing the opening such as to facilitate the insertion of the drill in the guided body; characterized in that the free end of the plate where the guide body is located forms an angle relative to the rest of the plate, and the guide body also constitutes a drill stop, so that the drill can be inserted into the bone tissue with the appropriate angle and depth. - A support; - A plate fastened on the support such that the plate can be moved and detached with respect to the support; - A rod comprising an upper end that is rotatably joined to the support that enable the relative movement between them, and a lower end that is insertable in the bone tissue of the mouth of the patient, - a guide body located at one of its free end; and - horizontal movement means formed by an elongated opening extending between the free end where the guide body is located and the free end opposite to the guided body, such that the assembly formed by the support and the rod can move along the opening in order to be able to vary the distance between the rod and the guide body,