mhurhangee/ep-ind-claims huggingface dataset:
Method of making a Fab library, the library comprising a plurality of vectors wherein each vector of the plurality of vectors comprises: - a first cloning region and a second cloning region, wherein - each cloning region comprises at least one, for the vector unique, restriction enzyme cleavage site, - each cloning region being 5' flanked by a ribosome binding site and a signal sequence, - a polynucleotide encoding an anchor region, located 3' of the second cloning region, - a polynucleotide encoding a constant heavy chain region or portion thereof located between the vector unique restriction enzyme cleavage site of the second cloning region and the anchor region, - a polynucleotide encoding a tag, the method comprising: introducing into the first cloning region a member of a first plurality of variable polynucleotides, said plurality of variable polynucleotides encoding a first plurality of polypeptides, wherein the member of the first plurality of polynucleotides encodes a polypeptide comprising an antibody light chain variable region possibly followed by an antibody light chain constant region, separately introducing into the second cloning region of each vector a member of a second plurality of variable polynucleotides, said plurality of variable polynucleotides encoding a second plurality of polypeptides, wherein the member of the second plurality of polynucleotides encodes a polypeptide comprising an antibody heavy chain variable region, and introducing each of the vectors into a host cell to provide a plurality of capsid particles each comprising a member of the first plurality of variable polynucleotides and a member of the second plurality of polynucleotides, to thereby make the library of antibodies or fragments thereof. - a first cloning region and a second cloning region, wherein - each cloning region comprises at least one, for the vector unique, restriction enzyme cleavage site, - each cloning region being 5' flanked by a ribosome binding site and a signal sequence, - a polynucleotide encoding an anchor region, located 3' of the second cloning region, - a polynucleotide encoding a constant heavy chain region or portion thereof located between the vector unique restriction enzyme cleavage site of the second cloning region and the anchor region, - each cloning region comprises at least one, for the vector unique, restriction enzyme cleavage site, - each cloning region being 5' flanked by a ribosome binding site and a signal sequence, - a polynucleotide encoding an anchor region, located 3' of the second cloning region, - a polynucleotide encoding a constant heavy chain region or portion thereof located between the vector unique restriction enzyme cleavage site of the second cloning region and the anchor region, - a polynucleotide encoding a tag, introducing into the first cloning region a member of a first plurality of variable polynucleotides, said plurality of variable polynucleotides encoding a first plurality of polypeptides, wherein the member of the first plurality of polynucleotides encodes a polypeptide comprising an antibody light chain variable region possibly followed by an antibody light chain constant region,
A method for determining virtual articulation from dental scans, the method being implemented on a processor and comprising steps of: receiving digital 3D models of a person's maxillary arch and mandibular arch; receiving digital 3D models of a plurality of different bite poses of the maxillary and mandibular arches (30, 31); and determining a virtual articulation model, based upon the digital 3D models of the plurality of different bite poses, including a pure rotation axis for each bite pose of the mandibular arch with respect to the maxillary arch, with mandibular arch movement for each bite pose being describable as a rotation about the pure rotation axis for the bite pose without an additional translation; wherein the step of receiving digital 3D models of a plurality of different bite poses includes receiving the digital 3D models for a closed bite pose, an open bite pose, a protrusive bite pose, a left lateral bite pose, and a right lateral bite pose. receiving digital 3D models of a person's maxillary arch and mandibular arch; receiving digital 3D models of a plurality of different bite poses of the maxillary and mandibular arches (30, 31); and determining a virtual articulation model, based upon the digital 3D models of the plurality of different bite poses, including a pure rotation axis for each bite pose of the mandibular arch with respect to the maxillary arch, with mandibular arch movement for each bite pose being describable as a rotation about the pure rotation axis for the bite pose without an additional translation; wherein the step of receiving digital 3D models of a plurality of different bite poses includes receiving the digital 3D models for a closed bite pose, an open bite pose, a protrusive bite pose, a left lateral bite pose, and a right lateral bite pose.
A method for transmitting information in a wireless communication system, comprising: generating a first portion of an interference report signal comprising a first sector-specific sequence multiplied by a single complex value X in a first OFDM symbol; and generating a second portion of the interference report signal comprising a second sector-specific sequence multiplied by another value Y, where Y is the square of X in a second OFDM symbol and wherein X depends on an observed value of interference. generating a first portion of an interference report signal comprising a first sector-specific sequence multiplied by a single complex value X in a first OFDM symbol; and generating a second portion of the interference report signal comprising a second sector-specific sequence multiplied by another value Y, where Y is the square of X in a second OFDM symbol and wherein X depends on an observed value of interference.
Device for manual locking of the wheel of a truck on a lane in front of a façade with a loading and unloading platform, comprising a guide provided alongside and parallel to the lane, extending from a road side to a façade side and a carriage movable on the guide, provided with a locking arm that is moveable between a starting position, in which the locking arm extends alongside the lane, and an end position, in which the locking arm partially extends above the lane and therein can rest blocking against the wheel of a truck, wherein the guide and the carriage are provided with co-operating locking means [16,19] for bringing about a locking of the carriage to the guide, whereby the device is provided with means by which, by moving of the locking arm from the starting position to the end position, the locking means are operated, whereby said means are formed by an adjusting organ that is movably connected to the carriage and onto which one of the locking means is mounted, characterized in that the adjusting organ further is provided with a cam roller co-operating with unevennesses provided in the surface of a part of the locking arm, in such a way, that by moving of the locking arm the cam roller is moved in and/or over the unevennesses, as a result of which the adjusting organ is brought into movement, and the locking means mounted to the adjusting organ is brought into and out of the engagement with the locking means provided onto the guide, whereby the carriage comprises a housing part, with respect to which the adjusting organ is movable to and fro, while at least one spring is provided, which on the one side is mounted to the housing part and on the other side to the adjusting organ, in such a way, that bringing the locking means that is mounted onto the adjusting organ into respectively out of engagement with the locking means that is provided to the guide takes place under respectively against spring force.
A milled and blended coffee product produced by the process of: i) introducing particles of a roasted coffee precursor into a milling chamber; ii) introducing particles of soluble coffee into the milling chamber; iii) jetting a gas into the milling chamber to mobilise the particles of the roasted coffee precursor and soluble coffee; iv) thereby producing a milled and blended coffee product by comminuting the particles of the roasted coffee precursor by self-collision of the particles of the roasted coffee precursor and by collision of the particles of soluble coffee with the particles of the roasted coffee precursor within the milling chamber. i) introducing particles of a roasted coffee precursor into a milling chamber; ii) introducing particles of soluble coffee into the milling chamber; iii) jetting a gas into the milling chamber to mobilise the particles of the roasted coffee precursor and soluble coffee; iv) thereby producing a milled and blended coffee product by comminuting the particles of the roasted coffee precursor by self-collision of the particles of the roasted coffee precursor
A user terminal comprising: a receiving section configured to receive in a given slot downlink control information, DCI, for scheduling reception and/or transmission of data in a physical shared channel, wherein the receiving section is further configured to receive Radio Resource Control, RRC, information comprising a set of semi-statically configured candidate values indicating an offset in number of slots from the given slot, further wherein the DCI includes a field dynamically designating a candidate value amongst the configured candidate values, whereby data is being scheduled in a slot determined from the given slot and the designated candidate value. a receiving section configured to receive in a given slot downlink control information, DCI, for scheduling reception and/or transmission of data in a physical shared channel, wherein the receiving section is further configured to receive Radio Resource Control, RRC, information comprising a set of semi-statically configured candidate values indicating an offset in number of slots from the given slot, further wherein the DCI includes a field dynamically designating a candidate value amongst the configured candidate values, whereby data is being scheduled in a slot determined from the given slot and the designated candidate value.
Method for producing a hybrid material (copolymer) comprising or consisting of the following steps: a. providing a first component comprising or consisting of one or more polyol(s) and one or more dilatants(s), wherein the one or more dilatants(s) comprises at least in part one or more amine group(s); b. providing a second component comprising one or more polyisocyanate(s); c. mixing the first and the second component to yield a reactive composition; d. curing the reactive composition to obtain the hybrid material. a. providing a first component comprising or consisting of one or more polyol(s) and one or more dilatants(s), wherein the one or more dilatants(s) comprises at least in part one or more amine group(s); b. providing a second component comprising one or more polyisocyanate(s); c. mixing the first and the second component to yield a reactive composition; d. curing the reactive composition to obtain the hybrid material.
Sealing and locking assembly (4; 5) for a flexible tubular joint of the type comprising a spigot end, a socket end, and at least one gasket, said sealing and locking assembly (4; 5) comprising a ready-to-mount locking assembly and a sealing mating flange, wherein said ready-to-mount locking assembly comprises: - a cylindrical locking mating flange, which is suitable for mounting on the spigot end by being threaded onto the spigot end and for delimiting an annular retaining chamber with the outer face of the spigot end, - means (52; 53) for assembling the locking mating flange with the sealing mating flange and with the socket end, - at least one retaining accessory, which is suitable for being positioned at least partially in said annular retaining chamber, and - clamping means, which make it possible to secure said retaining accessory to the spigot end by clamping the retaining accessory onto the spigot end, wherein the locking mating flange is suitable for axially locking, at least in the axial direction of disengagement of the spigot end, said retaining accessory which is positioned at least partially in said annular retaining chamber and secured to the spigot end, and wherein the sealing mating flange is suitable for mounting on the spigot end and for being joined to the socket end and to the locking mating flange of the ready-to-mount locking assembly, so as to compress, by means of the sealing mating flange, the gasket which is mounted between the socket of the socket end and the spigot end which is inserted coaxially into said socket of the socket end. - a cylindrical locking mating flange, which is suitable for mounting on the spigot end by being threaded onto the spigot end and for delimiting an annular retaining chamber with the outer face of the spigot end, - means (52; 53) for assembling the locking mating flange with the sealing mating flange and with the socket end, - at least one retaining accessory, which is suitable for being positioned at least partially in said annular retaining chamber, and - clamping means, which make it possible to secure said retaining accessory to the spigot end by clamping the retaining accessory onto the spigot end,
A mycovirus having 5 types of double-stranded RNAs, wherein the 5 types of double-stranded RNAs are polynucleotides comprising the nucleotide sequences represented by SEQ ID NOs: 1 to 5, respectively.
A substituted diphenylamine compound having general formula I: wherein: R 1 is selected from H or C 1 -C 6 alkyl; R 2 is selected from halogen, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylamino, C 1 -C 6 haloalkylamino, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio or C 2 -C 6 dialkylamino; R 3 is NO 2; R 4 and R 8 may be the same or different, respectively selected from H, halogen, CN, NO 2, C 1 -C 6 alkyl, or phenoxycarbonyl; R 5 and R 7 may be the same or different, respectively selected from H, halogen, C 1 -C 6 alkyl, or C 1 -C 6 haloalkyl; R 6 is selected from H, halogen, CN, NO 2, CO 2 H, C(=O)NR 9 R 10, C 1 -C 6 haloalkyl, C 1 -C 6 alkylcarbonyl, C 1 -C 6 alkoxycarbonyl, or pyridyloxy substituted with 1-4 R 11; but R 4, R 5, R 6, R 7 and R 8 cannot be H simultaneously; R 9 and Rio may be the same or different, respectively selected from H or C 1 -C 3 alkyl; R 11 is selected from halogen or C 1 -C 3 haloalkyl; or a salt of the compound having general formula I. R 1 is selected from H or C 1 -C 6 alkyl; R 2 is selected from halogen, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylamino, C 1 -C 6 haloalkylamino, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio or C 2 -C 6 dialkylamino; R 3 is NO 2; R 4 and R 8 may be the same or different, respectively selected from H, halogen, CN, NO 2, C 1 -C 6 alkyl, or phenoxycarbonyl; R 5 and R 7 may be the same or different, respectively selected from H, halogen, C 1 -C 6 alkyl, or C 1 -C 6 haloalkyl; R 6 is selected from H, halogen, CN, NO 2, CO 2 H, C(=O)NR 9 R 10, C 1 -C 6 haloalkyl, C 1 -C 6 alkylcarbonyl, C 1 -C 6 alkoxycarbonyl, or pyridyloxy substituted with 1-4 R 11; but R 4, R 5, R 6, R 7 and R 8 cannot be H simultaneously; R 9 and Rio may be the same or different, respectively selected from H or C 1 -C 3 alkyl; R 11 is selected from halogen or C 1 -C 3 haloalkyl;
A cathode material for use in thermal batteries, the cathode material comprising: NiS 2; and a primary cathode active material selected from the group consisting of a primary metal disulfide, a metal oxide and mixtures thereof, wherein the cathode material comprises an amount of electrolyte material, the electrolyte material comprising: at least 25 wt% lithium bromide; at least 4 wt% lithium chloride; at least 42 wt% lithium fluoride; and at least 1 wt% potassium bromide. NiS 2; and a primary cathode active material selected from the group consisting of a primary metal disulfide, a metal oxide and mixtures thereof, wherein the cathode material comprises an amount of electrolyte material, the electrolyte material comprising: at least 25 wt% lithium bromide; at least 4 wt% lithium chloride; at least 42 wt% lithium fluoride; and at least 1 wt% potassium bromide. at least 25 wt% lithium bromide; at least 4 wt% lithium chloride; at least 42 wt% lithium fluoride; and at least 1 wt% potassium bromide.
Method for transmitting a packet comprising at least one piece of information identifying a transmitter in an ad hoc network, the packet being intended for at least one receiver, characterized in that the method comprises the steps, carried out by the transmitter every time a packet is transmitted, of: - inserting, into the packet, a first signal for a predetermined first duration, the first signal being, in the baseband state, of the form: S t = Ae i 2 πf S t + iφ where t ∈ [0, T S] is the time interval over which the first signal is defined, A is amplitude, f S is the frequency of the first signal in the baseband state and φ ∈ [0,2 π] is an arbitrarily chosen phase, the first signal enabling frequency synchronization by the receiver, - inserting, into the packet, a second signal having the characteristics of a frequency-modulated signal the centre frequency of which is equal to the frequency of the first signal, the second signal being obtained on the basis of a phase defined on the basis of a pseudoperiodic signal, the second signal having been allocated to the transmitter beforehand and having a predetermined second duration, the second signal being different from and orthogonal to every other second signal allocated to other transmitters and enabling time synchronization by the receiver, - inserting, into the packet, data in association with the first and second signals, - transferring the packet after transposition into a frequency plane over a radio medium. - inserting, into the packet, a first signal for a predetermined first duration, the first signal being, in the baseband state, of the form: S t = Ae i 2 πf S t + iφ where t ∈ [0, T S] is the time interval over which the first signal is defined, A is amplitude, f S is the frequency of the first signal in the baseband state and φ ∈ [0,2 π] is an arbitrarily chosen phase, the first signal enabling frequency synchronization by the receiver, where t ∈ [0, T S] is the time interval over which the first signal is defined, A is amplitude, f S is the frequency of the first signal in the baseband state and φ ∈ [0,2 π] is an arbitrarily chosen phase, the first signal enabling frequency synchronization by the receiver, - inserting, into the packet, a second signal having the characteristics of a frequency-modulated signal the centre frequency of which is equal to the frequency of the first signal, the second signal being obtained on the basis of a phase defined on the basis of a pseudoperiodic signal, the second signal having been allocated to the transmitter beforehand and having a predetermined second duration, the second signal being different from and orthogonal to every other second signal allocated to other transmitters and enabling time synchronization by the receiver, - inserting, into the packet, data in association with the first and second signals, - transferring the packet after transposition into a frequency plane over a radio medium.
An actuator comprising: - at least one cooler (3a, 3b); - at least one turbo compressor stage (1a, 1b) with an outlet for conveying gas compressed in said at least one turbo compressor stage (1a, 1b) to said at least one cooler (3a, 3b); - a shaft for rotating said at least one stage of turbo compressor (1a, 1b) for increasing the pressure of the gas to be supplied to the actuator; - a turbine; and - a control valve, by means of which the flow of compressed gas produced by the turbo compressor (1a, 1b) to the turbine is arranged to be adjusted, characterized in that the actuator further comprises a motor arranged to rotate said shaft, and that the actuator is adapted to use the gas that has flowed through the turbine for cooling at least one of the following: - the motor of the turbo compressor; - an auxiliary device. - at least one cooler (3a, 3b); - at least one turbo compressor stage (1a, 1b) with an outlet for conveying gas compressed in said at least one turbo compressor stage (1a, 1b) to said at least one cooler (3a, 3b); - a shaft for rotating said at least one stage of turbo compressor (1a, 1b) for increasing the pressure of the gas to be supplied to the actuator; - a turbine; and - a control valve, by means of which the flow of compressed gas produced by the turbo compressor (1a, 1b) to the turbine is arranged to be adjusted, - the motor of the turbo compressor; - an auxiliary device.
The compound 2-methoxy-3-(4'-aminophenyl) propionic acid (compound 34) represented by the formula: or a pharmaceutically acceptable salt or a stereoisomer thereof, for use in the treatment of fibrosis, wherein the fibrosis is selected from intestinal fibrosis or idiopathic pulmonary fibrosis.
A method for producing tolylene diisocyanate containing 2,4-tolylene diisocyanate and 2,6-tolylene diisocyanate at a target isomer ratio, the method comprising: mixing a first diaminotoluene containing 2,4-diaminotoluene and 2,6-diaminotoluene at a first isomer ratio and a second diaminotoluene containing 2,4-diaminotoluene and/or 2,6-diaminotoluene at a second isomer ratio that is different from the first isomer ratio so as to prepare mixed diaminotoluene; producing tolylene dicarbamate by reaction of the mixed diaminotoluene, urea and/or N-unsubstituted carbamic acid ester and alcohol; and thermally decomposing the tolylene dicarbamate, wherein the target isomer ratio is 2,4-tolylene diisocyanate/2,6-tolylene diisocyanate (molar ratio) = 75 to 85/25 to 15, the first isomer ratio is 2,4-diaminotoluene/2,6-diaminotoluene (molar ratio) = 75 to 85/25 to 15, the proportion (molar ratio) of 2,4-diaminotoluene in the second isomer ratio is higher than the proportion (molar ratio) of 2,4-diaminotoluene in the first isomer ratio by 5 to 25, the proportion (molar ratio) of 2,4-diaminotoluene in the mixed diaminotoluene is higher than the proportion (molar ratio) of 2,4-tolylene diisocyanate in the target isomer ratio of the tolylene diisocyanate, and the second diaminotoluene is used in an amount of 1 to 50 parts by mass per 100 parts by mass of the first diaminotoluene. mixing a first diaminotoluene containing 2,4-diaminotoluene and 2,6-diaminotoluene at a first isomer ratio and a second diaminotoluene containing 2,4-diaminotoluene and/or 2,6-diaminotoluene at a second isomer ratio that is different from the first isomer ratio so as to prepare mixed diaminotoluene; producing tolylene dicarbamate by reaction of the mixed diaminotoluene, urea and/or N-unsubstituted carbamic acid ester and alcohol; and thermally decomposing the tolylene dicarbamate, wherein the target isomer ratio is 2,4-tolylene diisocyanate/2,6-tolylene diisocyanate (molar ratio) = 75 to 85/25 to 15, the first isomer ratio is 2,4-diaminotoluene/2,6-diaminotoluene (molar ratio) = 75 to 85/25 to 15, the proportion (molar ratio) of 2,4-diaminotoluene in the second isomer ratio is higher than the proportion (molar ratio) of 2,4-diaminotoluene in the first isomer ratio by 5 to 25, the proportion (molar ratio) of 2,4-diaminotoluene in the mixed diaminotoluene is higher than the proportion (molar ratio) of 2,4-tolylene diisocyanate in the target isomer ratio of the tolylene diisocyanate, and the second diaminotoluene is used in an amount of 1 to 50 parts by mass per 100 parts by mass of the first diaminotoluene.