mhurhangee/ep-ind-claims huggingface dataset:
A transducer comprising an emitter device for emitting torsional ultrasonic waves, wherein the emitter device comprises an electrical signal generator connected to an electromechanical actuator which is in turn attached to an element that comes into contact with a specimen, such that when the actuator receives electrical signals, it induces rotational movement of the contact element, and when said contact element comes into contact with the specimen, it induces a torsional wave that goes through said specimen; and wherein the transducer further comprises means for receiving the distorted signal after it goes through the specimen and is characterized in that the means for receiving the distorted signal comprise two or more piezoelectric elements located equidistant from one another and placed between two rings (4a and 4b) made from a non-conducting material and in that the axis of rotation of the rings coincides with the axis of rotation of the electromechanical actuator; wherein an attenuating element, preferably an attenuating resin, is fixed to the outer face of the ring that is the farthest away from the area of contact with the specimen; and wherein the contact element has a considerably frustoconical shape such that its smaller base (b) is attached to the electromechanical actuator and its larger base is arranged at the distal end of the transducer of the invention so that it comes into contact with the specimen on which shear wave is to be transmitted.
A multi-valued magnetic storage apparatus, comprising a magnetic storage track, a first write apparatus, a second write apparatus, and a drive apparatus, wherein the magnetic storage track is configured to store data; the drive apparatus is connected to the magnetic storage track and is configured to send a drive signal to the magnetic storage track, to drive magnetic domains in the magnetic storage track to move; the first write apparatus and the second write apparatus are separately located at different positions on the magnetic storage track; the first write apparatus is configured to write first data or second data to a magnetic domain moving to the first write apparatus, wherein the first data is represented by a first magnetization direction of the magnetic domain moving to the first write apparatus, the second data is represented by a second magnetization direction of the magnetic domain moving to the first write apparatus, and the first magnetization direction is opposite to the second magnetization direction; and the second write apparatus is configured to write third data or fourth data to a magnetic domain moving to the second write apparatus, wherein the third data is represented by a third magnetization direction of the magnetic domain moving to the second write apparatus, the fourth data is represented by a fourth magnetization direction of the magnetic domain moving to the second write apparatus, the third magnetization direction is opposite to the fourth magnetization direction, and the first magnetization direction, the second magnetization direction, the third magnetization direction, and the fourth magnetization direction are different from each other, wherein the first magnetization direction, the second magnetization direction, the third magnetization direction and the fourth magnetization direction are parallel to planes in which magnetic domain walls are located.
A fuel cell system comprising: a source of fuel; a fuel desulfurization system fluidly coupled to the source of fuel to receive the fuel in a gaseous phase, the fuel desulfurization system including a fuel condenser that condenses at least a portion of the fuel from the gaseous phase to a liquid phase; a reformer fluidly coupled to the fuel desulfurization system that receives the fuel from the fuel desulfurization system in the liquid phase to generate hydrogen enriched fuel; and a fuel cell stack fluidly coupled to the reformer to receive the hydrogen enriched fuel, wherein the fuel condenser is fluidly coupled to the fuel source and a remainder of the uncondensed fuel in the gaseous phase is returned from the fuel condenser to the source of fuel to inert the source of fuel. a source of fuel; a fuel desulfurization system fluidly coupled to the source of fuel to receive the fuel in a gaseous phase, the fuel desulfurization system including a fuel condenser that condenses at least a portion of the fuel from the gaseous phase to a liquid phase; a reformer fluidly coupled to the fuel desulfurization system that receives the fuel from the fuel desulfurization system in the liquid phase to generate hydrogen enriched fuel; and a fuel cell stack fluidly coupled to the reformer to receive the hydrogen enriched fuel, wherein the fuel condenser is fluidly coupled to the fuel source and a remainder of the uncondensed fuel in the gaseous phase is returned from the fuel condenser to the source of fuel to inert the source of fuel.
Dextromethorphan or Dextrorphan, or a pharmaceutically acceptable salt of either thereof, for use in a method for treatment or prevention of symptoms of hormonal variation, said method comprising identifying a subject having one or more symptoms of hormonal variations selected from hot flashes and night sweats and administering an effective amount of said Dextromethorphan or Dextrorphan or salt to the subject.
A household liquid-dispensing container such as a drinking vessel, flask or a jug comprising: - a vessel that is configured to hold a liquid and that has a base on which it can stand, an opening and at least one side; and - a handle that is configured to be held by a user and that is attached to a side of the vessel by a joint that comprises a low friction bearing and forms a single gimbal between the handle and the vessel and that allows the handle to pivot about a single axis that extends directly above the centre of gravity of the vessel when the vessel base is standing on a horizontal surface. wherein the handle is attached to a side of the vessel by a single joint - a vessel that is configured to hold a liquid and that has a base on which it can stand, an opening and at least one side; and - a handle that is configured to be held by a user and that is attached to a side of the vessel by a joint that comprises a low friction bearing and forms a single gimbal between the handle and the vessel and that allows the handle to pivot about a single axis that extends directly above the centre of gravity of the vessel when the vessel base is standing on a horizontal surface.
Facility for supplying subcooled cryogenic liquid to at least one station (P, P1, P2...) carrying out machining operations, comprising a storage tank, tank which contains, under a storage pressure greater than atmospheric pressure, the cryogenic fluid in the liquid phase at the bottom of the tank and in the gaseous phase at the top of the tank, said tank being suitable for supplying said station (P, P1, P2...) with liquid drawn from the bottom of the tank, as well as for being provided with fluid from the outside, and comprising - at least one heat exchanger, submerged in at least one pool of said cryogenic liquid, - means for controlling (3, 4) the level of the or each pool at a predefined level; - a system of pipelines capable of passing through the or each heat exchanger cryogenic liquid coming from the storage tank before the arrival thereof at said machining station(s); - means making it possible to regulate (1, 6, 1 1, 1 2, 6 1, 6 2...) the pressure of the cryogenic liquid from the or each submerged exchanger before the arrival thereof at said corresponding machining station; - a valve (1, 1 1, 1 2) located upstream of the arrival of liquid in each one of said exchangers, with each valve being in fluidic communication with said tank, characterised in that said means that make it possible to regulate the pressure of the cryogenic liquid coming from the or each submerged exchanger before the arrival thereof at said corresponding machining station comprise a dedicated pressure sensor (6, 6 1, 6 2...), positioned between the outlet of each exchanger and said machining station (P, P1, P2..) associated with the exchanger considered, and configured to provide the information that it measures to said valve (1, 1 1, 1 2,) located upstream of the arrival of the liquid in the exchanger considered. - at least one heat exchanger, submerged in at least one pool of said cryogenic liquid, - means for controlling (3, 4) the level of the or each pool at a predefined level; - a system of pipelines capable of passing through the or each heat exchanger cryogenic liquid coming from the storage tank before the arrival thereof at said machining station(s); - means making it possible to regulate (1, 6, 1 1, 1 2, 6 1, 6 2...) the pressure of the cryogenic liquid from the or each submerged exchanger before the arrival thereof at said corresponding machining station; - a valve (1, 1 1, 1 2) located upstream of the arrival of liquid in each one of said exchangers, with each valve being in fluidic communication with said tank,
Use of an isolated envelope glycoprotein of HIV-1 strain BG505, engineered to have a L to A substitution at the position corresponding to L111 in the env of HIV-1 strain HxB2, and optionally a T to N substitution at the position corresponding to N332 in the env of HIV-1 strain HxB2 when the env sequences of BG505 and HxB2 are aligned for screening broad neutralizing antibodies comprising contacting such glycoprotein with an animal or human sera, isolating the glycoprotein complexed to the broad neutralizing antibodies, thereby screening for a broad neutralizing antibody.
The compound having formula, wherein A is a peptide having 1 to 10 amino acids and B is a Peptide bond; or a pharmaceutically acceptable salt thereof. A is a peptide having 1 to 10 amino acids and B is a Peptide bond;
A positive electrode material comprising: a positive electrode active material mixture comprising a positive electrode active material prepared with an active material precursor and a lithium compound, a conductive agent, and a binder; and an active material precursor as an additive, wherein the active material precursor as the additive is the same substance as the active material precursor used as the precursor material of the positive electrode active material. a positive electrode active material mixture comprising a positive electrode active material prepared with an active material precursor and a lithium compound, a conductive agent, and a binder; and an active material precursor as an additive, wherein the active material precursor as the additive is the same substance as the active material precursor used as the precursor material of the positive electrode active material.
A cyclodextrin inclusion complex delivery vehicle, comprising: an alpha cyclodextrin having a cavity; a butyric acid molecule, or a glyceride thereof, that is at least partially retained as a guest molecule within the cavity of the cyclodextrin, forming a cyclodextrin inclusion complex; a pharmaceutically acceptable carrier for the cyclodextrin inclusion complex, wherein the guest molecule is stably retained by the cyclodextrin within the pharmaceutically acceptable carrier; and, a microbial amylase enzyme having a cyclodextrin-degrading activity capable of digesting the cyclodextrin retaining the guest molecule, wherein the microbial amylase enzyme is co-formulated with the cyclodextrin inclusion complex so that the cyclodextrin-degrading activity is activated on oral delivery of the vehicle to a human patient so as to release the guest molecule from the cyclodextrin cavity. an alpha cyclodextrin having a cavity; a butyric acid molecule, or a glyceride thereof, that is at least partially retained as a guest molecule within the cavity of the cyclodextrin, forming a cyclodextrin inclusion complex; a pharmaceutically acceptable carrier for the cyclodextrin inclusion complex, wherein the guest molecule is stably retained by the cyclodextrin within the pharmaceutically acceptable carrier; and, a microbial amylase enzyme having a cyclodextrin-degrading activity capable of digesting the cyclodextrin retaining the guest molecule, wherein the microbial amylase enzyme is co-formulated with the cyclodextrin inclusion complex so that the cyclodextrin-degrading activity is activated on oral delivery of the vehicle to a human patient so as to release the guest molecule from the cyclodextrin cavity.
An Fc construct comprising: a) a first polypeptide having the formula A-L-B; wherein i) A comprises a first Fc domain monomer; ii) L is a glycine spacer; and iii) B comprises a second Fc domain monomer; b) a second polypeptide having the formula A'-L'-B'; wherein i) A' comprises a third Fc domain monomer; ii) L' is a glycine spacer; and iii) B' comprises a fourth Fc domain monomer; c) a third polypeptide that comprises a fifth Fc domain monomer; and d) a fourth polypeptide that comprises a sixth Fc domain monomer; wherein each of the first and second polypeptides have the amino acid sequence: each of the third and fourth polypeptides have the amino acid sequence: and B and B' combine to form a first Fc domain, A and the fifth Fc domain monomer combine to form a second Fc domain, and A' and the sixth Fc domain monomer combine to form a third Fc domain. a) a first polypeptide having the formula A-L-B; wherein i) A comprises a first Fc domain monomer; ii) L is a glycine spacer; and iii) B comprises a second Fc domain monomer; i) A comprises a first Fc domain monomer; ii) L is a glycine spacer; and iii) B comprises a second Fc domain monomer; b) a second polypeptide having the formula A'-L'-B'; wherein i) A' comprises a third Fc domain monomer; ii) L' is a glycine spacer; and iii) B' comprises a fourth Fc domain monomer; i) A' comprises a third Fc domain monomer; ii) L' is a glycine spacer; and iii) B' comprises a fourth Fc domain monomer; c) a third polypeptide that comprises a fifth Fc domain monomer; and d) a fourth polypeptide that comprises a sixth Fc domain monomer; each of the first and second polypeptides have the amino acid sequence: each of the third and fourth polypeptides have the amino acid sequence: and B and B' combine to form a first Fc domain, A and the fifth Fc domain monomer combine to form a second Fc domain, and A' and the sixth Fc domain monomer combine to form a third Fc domain.
A method for increasing the degree of glycosylation of a composition comprising steviol glycosides, wherein the composition comprising steviol glycosides is a plant extract or a composition of fermentatively produced steviol glycosides, wherein the increase in the degree of glycosylation of the composition comprising steviol glycosides is an increase in the amount of rebaudioside A, rebaudioside D or rebaudioside M present in the composition comprising steviol glycosides, which method comprises: a. contacting said composition comprising steviol glycosides with a recombinant microorganism, a cell free extract derived from such a recombinant microorganism or an enzyme preparation derived from either thereof, wherein the recombinant microorganism is provided in the form of spent biomass from a fermentation process in which steviol glycosides are produced; and b. thereby to increase the degree of glycosylation of the composition comprising steviol glycosides, wherein the recombinant microorganism comprises one or more nucleotide sequence(s) encoding: a polypeptide having ent-copalyl pyrophosphate synthase activity; a polypeptide having ent-Kaurene synthase activity; a polypeptide having ent-Kaurene oxidase activity; a polypeptide having kaurenoic acid 13-hydroxylase activity; and one or more polypeptides having UDP-glucosyltransferase activity whereby expression of the nucleotide sequence(s) confer(s) on the microorganism the ability to produce at least one steviol glycoside. a. contacting said composition comprising steviol glycosides with a recombinant microorganism, a cell free extract derived from such a recombinant microorganism or an enzyme preparation derived from either thereof, wherein the recombinant microorganism is provided in the form of spent biomass from a fermentation process in which steviol glycosides are produced; and b. thereby to increase the degree of glycosylation of the composition comprising steviol glycosides, wherein the recombinant microorganism comprises one or more nucleotide sequence(s) encoding: a polypeptide having ent-copalyl pyrophosphate synthase activity; a polypeptide having ent-Kaurene synthase activity; a polypeptide having ent-Kaurene oxidase activity; a polypeptide having kaurenoic acid 13-hydroxylase activity; and one or more polypeptides having UDP-glucosyltransferase activity whereby expression of the nucleotide sequence(s) confer(s) on the microorganism the ability to produce at least one steviol glycoside. a polypeptide having ent-copalyl pyrophosphate synthase activity; a polypeptide having ent-Kaurene synthase activity; a polypeptide having ent-Kaurene oxidase activity; a polypeptide having kaurenoic acid 13-hydroxylase activity; and one or more polypeptides having UDP-glucosyltransferase activity whereby expression of the nucleotide sequence(s) confer(s) on the microorganism the ability to produce at least one steviol glycoside.
Hot-rolled flat steel product, which is 2 - 12 mm thick and has a minimum yield strength of 900 MPa, an elongation at break of at least 8 %, a tensile strength of 950 - 1300 MPa and a notch impact energy at - 40°C of 40 - 120 J, having a ferrite-free, bainitic-martensitic structure, which consists of at least 95 % by volume of martensite and bainite with a martensite proportion of at least 5 % by volume and has, as the remainder, up to 5 % by volume of residual austenite as well as unavoidable structural constituents from the production process, and having a composition, which consists of the following (in % by weight), in addition to iron and unavoidable impurities: C: 0.08-0.10% Si: 0.015-0.50 % Mn: 1.20-2.00% Al: 0.020-0.040% Cr: 0.30-1.00% Mo: 0.20-0.30% Nb: 0.020-0.030% B: 0.0015 - 0.0025 % P: up to 0.025 % S: up to 0.010% N: up to 0.006% wherein the impurities include up to 0.12 % Cu, up to 0.090 % Ni, up to 0.0030 % Ti, up to 0.009 % V, up to 0.0090 % Co, up to 0.004 % Sb and up to 0.0009 % W and wherein the following applies to the carbon equivalent CE | |W of the composition thereof: CE ∥ W ≤ 0.5 where CE ∥ W = % ⁢ C + % ⁢ Mn / 6 + % Cr + % Mo + % V / 5 + % Cu + % Ni / 15 where %C denotes the respective C content in % by weight, %Mn denotes the respective Mn content in % by weight, %Cr denotes the respective Cr content in % by weight, %Mo denotes the respective Mo content in % by weight, %V denotes the respective V content in % by weight, %Cu denotes the respective Cu content in % by weight, and %Ni denotes the respective Ni content in % by weight. %C denotes the respective C content in % by weight, %Mn denotes the respective Mn content in % by weight, %Cr denotes the respective Cr content in % by weight, %Mo denotes the respective Mo content in % by weight, %V denotes the respective V content in % by weight, %Cu denotes the respective Cu content in % by weight, and %Ni denotes the respective Ni content in % by weight.
A method for signaling and verifying Uniform Resource Locator, URL, signatures for accessing URL addressable content in adaptive streaming, the method comprising: providing a plurality of URL authentication and URL authorization descriptors for a plurality of URLs, wherein each URL authentication descriptor comprises information for verification key acquisition and for accessing an authentication tag for authenticating a given URL in the plurality of URLs according to an associated URL authentication scheme, and each URL authorization descriptor is for verification key acquisition and for accessing an authorization tag for authorizing access to content addressable by a given URL in the plurality of URLs according to an associated URL authentication scheme; communicating the plurality of URL authentication and URL authorization descriptors for the plurality of URLs; and, verifying each descriptor in the communicated plurality of URL authentication and URL authorization descriptors for its given URL in the plurality of URLs according to its associated scheme. providing a plurality of URL authentication and URL authorization descriptors for a plurality of URLs, wherein each URL authentication descriptor comprises information for verification key acquisition and for accessing an authentication tag for authenticating a given URL in the plurality of URLs according to an associated URL authentication scheme, and each URL authorization descriptor is for verification key acquisition and for accessing an authorization tag for authorizing access to content addressable by a given URL in the plurality of URLs according to an associated URL authentication scheme; communicating the plurality of URL authentication and URL authorization descriptors for the plurality of URLs; and, verifying each descriptor in the communicated plurality of URL authentication and URL authorization descriptors for its given URL in the plurality of URLs according to its associated scheme.
A method of allylic oxidation, characterized in that a bicyclic compound reactant with the following general Structure I: is oxidized with an oxygen-containing gas in presence of a metal-organic compound and a supported gold catalyst, in order to obtain an α,β-unsaturated ketone and/or alcohol, wherein a carbonyl and/or a carbinol group is in the Y-containing ring, said ketone and/or alcohol having the following Structures II and III: wherein R 1, R 2, R 3 and R 4 stand for alkyl groups, X stands for -CHR 5 - or - CHR 5 -CHR 6 -, Y stands for -CHR 7 - or -CHR 7 -CHR 8 - and R 5, R 6, R 7 and R 8 stand for hydrogen or alkyl groups, and wherein the metal-organic compound contains one or more metal atoms and between 4 and 30 carbon atoms.