An IV-solution delivery system 10 for intravenous delivery of a hazardous solution 16, the system comprising: a coupling assembly 20 having an input 62 and an output 64, the input 62 configured for coupling to a primary fluid reservoir 12 to provide flow of a hazardous solution 16 from the primary fluid reservoir 12 to the output 64; a drip chamber 40 having an input 46 and an output 48, the input 46 of the drip chamber 40 coupled to the output 64 of the coupling assembly 20 to receive fluid from the flow of the fluid from the primary fluid reservoir 12 to form a secondary fluid reservoir 42 within the drip chamber 40, the output 48 of the drip chamber 40 being configured to receive a patient conduit 50; and a membrane 66 interposedly positioned between the secondary fluid reservoir 42 and the output 48 of the drip chamber 40, wherein the membrane 66 prevents passage of air from the drip chamber 40 to the output 48 of the drip chamber 40; wherein the system 10 includes a self-sealing priming port 44 in fluid communication with the interior of drip chamber 40, coupled to an outer surface thereof and further including an opening 190 for receiving a tip portion 182 of a syringe 180, the priming port 44 having a split septum 184 which forms an airtight seal thereby maintaining pressure within the drip chamber 40 and the remainder of the IV delivery system 10 and which is configured to be biased to an opened position by inserting a tip portion 182 of a syringe 180 into the opening 190 of priming port 44, said syringe 180 being configured to deliver a priming/flushing solution 160 directly to the drip chamber 40 to flush the patient conduit 50 to remove hazardous material 16 from the delivery system 10 and into the patient 100 following the infusion procedure; and in that the patient conduit 50 comprises (a) a first end coupled to the output 48 of the drip chamber 40; and (b) a second, terminal end 54 to which a vent membrane 158 is directly coupled; characterized in that the second end 54 of the patient conduit 50 is so configured that vent membrane 158 is automatically defeated upon coupling of a luer device to said second end 54 thereby resuming fluid flow through the patient conduit 50. a coupling assembly 20 having an input 62 and an output 64, the input 62 configured for coupling to a primary fluid reservoir 12 to provide flow of a hazardous solution 16 from the primary fluid reservoir 12 to the output 64; a drip chamber 40 having an input 46 and an output 48, the input 46 of the drip chamber 40 coupled to the output 64 of the coupling assembly 20 to receive fluid from the flow of the fluid from the primary fluid reservoir 12 to form a secondary fluid reservoir 42 within the drip chamber 40, the output 48 of the drip chamber 40 being configured to receive a patient conduit 50; and a membrane 66 interposedly positioned between the secondary fluid reservoir 42 and the output 48 of the drip chamber 40, wherein the membrane 66 prevents passage of air from the drip chamber 40 to the output 48 of the drip chamber 40; (a) a first end coupled to the output 48 of the drip chamber 40; and (b) a second, terminal end 54 to which a vent membrane 158 is directly coupled;