A method for assessing liver fibrosis progression in an individual, wherein said method is non-invasive, meaning that no tissue is taken from the body of said individual and wherein liver fibrosis progression is defined as the evolution of the fibrosis level over time, said method comprising the steps of calculating the ratio of fibrosis level to cause duration, wherein cause duration is the time between the age when the cause started and the age at inclusion when fibrosis level was measured, and cause is hepatitis viral infection or non-alcoholic fatty liver disease (NAFLD) or alcohol, and wherein said fibrosis level is a fibrosis score or an Area of Fibrosis score, wherein: - the fibrosis score is a score obtained by combining in a logistic or linear regression function the following markers: ∘ when the cause is hepatitis viral infection: age, sex, α-2 macroglobulin (A2M), hyaluronate, prothrombin index, platelet, aspartate amino-transferase, urea and gamma-glutamyltranspeptidase; ∘ when the cause is alcohol: age, α-2 macroglobulin (A2M), hyaluronate and prothrombin index; ∘ when the cause is NAFLD: age, body weight, platelet, aspartate amino-transferase, alanine amino-transferase, ferritin and glycemia; - the Area of Fibrosis score is a score obtained by combining in a logistic or linear regression function the following markers: ∘ when the cause is hepatitis viral infection: α-2 macroglobulin (A2M), hyaluronate, platelet, urea, gamma-glutamyltranspeptidase and bilirubin; ∘ when the cause is alcohol: α-2 macroglobulin (A2M), hyaluronate, prothrombin index and platelet; ∘ when the cause is NAFLD: prothrombin index, platelet, aspartate amino-transferase, alanine amino-transferase and glycemia. - the fibrosis score is a score obtained by combining in a logistic or linear regression function the following markers: ∘ when the cause is hepatitis viral infection: age, sex, α-2 macroglobulin (A2M), hyaluronate, prothrombin index, platelet, aspartate amino-transferase, urea and gamma-glutamyltranspeptidase; ∘ when the cause is alcohol: age, α-2 macroglobulin (A2M), hyaluronate and prothrombin index; ∘ when the cause is NAFLD: age, body weight, platelet, aspartate amino-transferase, alanine amino-transferase, ferritin and glycemia; ∘ when the cause is hepatitis viral infection: age, sex, α-2 macroglobulin (A2M), hyaluronate, prothrombin index, platelet, aspartate amino-transferase, urea and gamma-glutamyltranspeptidase; ∘ when the cause is alcohol: age, α-2 macroglobulin (A2M), hyaluronate and prothrombin index; ∘ when the cause is NAFLD: age, body weight, platelet, aspartate amino-transferase, alanine amino-transferase, ferritin and glycemia; - the Area of Fibrosis score is a score obtained by combining in a logistic or linear regression function the following markers: ∘ when the cause is hepatitis viral infection: α-2 macroglobulin (A2M), hyaluronate, platelet, urea, gamma-glutamyltranspeptidase and bilirubin; ∘ when the cause is alcohol: α-2 macroglobulin (A2M), hyaluronate, prothrombin index and platelet; ∘ when the cause is NAFLD: prothrombin index, platelet, aspartate amino-transferase, alanine amino-transferase and glycemia. ∘ when the cause is hepatitis viral infection: α-2 macroglobulin (A2M), hyaluronate, platelet, urea, gamma-glutamyltranspeptidase and bilirubin; ∘ when the cause is alcohol: α-2 macroglobulin (A2M), hyaluronate, prothrombin index and platelet; ∘ when the cause is NAFLD: prothrombin index, platelet, aspartate amino-transferase, alanine amino-transferase and glycemia.