mhurhangee/ep-ind-claims huggingface dataset:
Device for sampling cellular biomarkers, comprising: - at least one device for capturing cellular biomarkers, suitable for use in vivo and comprising: - filtration means for retaining said cellular biomarkers, said filtration means comprising at least one through opening, the dimensions of which are adapted to retain said cellular biomarkers selected from the group consisting of stromal cells, epithelial cells, circulating foetal cells, stem cells, clusters or aggregates of tumour cells, tumour cells associated with all types of cancer and other cell types: monocytes, macrophages, and - said filtration means is integral with a support taking the form of a hollow part open at one end and closed at the other end by the filtration means, and having a symmetry of revolution about an axis (X-X') which is totally or truncated in a plane parallel to the axis (X-X'), the filtration means forming the bottom of the support, said capture device being attached to a means for introducing said capture device into a biological flow vessel. - at least one device for capturing cellular biomarkers, suitable for use in vivo and comprising: - filtration means for retaining said cellular biomarkers, said filtration means comprising at least one through opening, the dimensions of which are adapted to retain said cellular biomarkers selected from the group consisting of stromal cells, epithelial cells, circulating foetal cells, stem cells, clusters or aggregates of tumour cells, tumour cells associated with all types of cancer and other cell types: monocytes, macrophages, and - said filtration means is integral with a support taking the form of a hollow part open at one end and closed at the other end by the filtration means, and having a symmetry of revolution about an axis (X-X') which is totally or truncated in a plane parallel to the axis (X-X'), the filtration means forming the bottom of the support, - filtration means for retaining said cellular biomarkers, said filtration means comprising at least one through opening, the dimensions of which are adapted to retain said cellular biomarkers selected from the group consisting of stromal cells, epithelial cells, circulating foetal cells, stem cells, clusters or aggregates of tumour cells, tumour cells associated with all types of cancer and other cell types: monocytes, macrophages, and - said filtration means is integral with a support taking the form of a hollow part open at one end and closed at the other end by the filtration means, and having a symmetry of revolution about an axis (X-X') which is totally or truncated in a plane parallel to the axis (X-X'), the filtration means forming the bottom of the support,
A method for preventing fluid and gas flow through a wellbore space around an axis and defined by an inner casing and an outer casing which surrounds the inner casing, the method comprising the steps of: • preparing a cement slurry to be injected into the wellbore space, characterised by: • placing a cement slurry supply line into the wellbore space between the casings, the supply line having at least two lateral outlets providing at least bi-directional flow of the cement slurry away from the supply line; and • injecting the cement slurry into the wellbore through the supply line and the at least two lateral outlets; and • flowing the cement slurry simultaneously at least bi- directionally in both clockwise and counterclockwise directions around the wellbore space generally orthogonal to the axis with minimal axial flow to completely fill an axial region of the wellbore space thereby forming a solid plug between the casings which prevents fluid and gas flow through the wellbore, the cement slurry rapidly transitioning from a flowable state to a solid state to form the plug with formation of little or no gel strength before the transition and having a near-linear relationship between the time required for the transition to occur and the composition temperature at which the transition occurs. • preparing a cement slurry to be injected into the wellbore space, characterised by: • placing a cement slurry supply line into the wellbore space between the casings, the supply line having at least two lateral outlets providing at least bi-directional flow of the cement slurry away from the supply line; and • injecting the cement slurry into the wellbore through the supply line and the at least two lateral outlets; and • flowing the cement slurry simultaneously at least bi- directionally in both clockwise and counterclockwise directions around the wellbore space generally orthogonal to the axis with minimal axial flow to completely fill an axial region of the wellbore space thereby forming a solid plug between the casings which prevents fluid and gas flow through the wellbore, the cement slurry rapidly transitioning from a flowable state to a solid state to form the plug with formation of little or no gel strength before the transition and having a near-linear relationship between the time required for the transition to occur and the composition temperature at which the transition occurs.
A method, performed by a wireless device, for performing an uplink transmission, the method comprising: determining whether a serving-cell signal measurement M2 was completed within a predetermined range of time before and no later than a reference time T2, the reference time T2 corresponding to an uplink transmission opportunity; and, responsive to determining that the serving-cell signal measurement M2 was not completed within the predetermined range of time, either deferring transmission to a subsequent uplink transmission opportunity, or dropping the uplink transmission, or collecting an additional serving-cell measurement M2' that falls within the predetermined range of time. determining whether a serving-cell signal measurement M2 was completed within a predetermined range of time before and no later than a reference time T2, the reference time T2 corresponding to an uplink transmission opportunity; and, responsive to determining that the serving-cell signal measurement M2 was not completed within the predetermined range of time, either deferring transmission to a subsequent uplink transmission opportunity, or dropping the uplink transmission, or collecting an additional serving-cell measurement M2' that falls within the predetermined range of time.
A method of determining acid glucosidase activity in a subject, the method comprising the steps of: (a) extracting acid glucosidase from a dried blood spot obtained from the subject using an aqueous buffer solution; (b) adding an assay mix comprising substrate, an internal standard, detergent, buffer and acarbose to the extracted acid glucosidase, wherein the molar ratio of substrate to internal standard is 100:1, the molar ratio of detergent to substrate is 24.3:1, the molar ratio of buffer to substrate is 450:1 and the molar ratio of acarbose to substrate is 0.02:1; (c) reacting the substrate with the extracted acid glucosidase; (d) quenching the reaction by addition of four volumes of a solution consisting essentially of ethyl acetate/methanol (1/1); (e) extracting the reaction product and internal standard by adding at least about a 3/5 volume of ethyl acetate and at least about a 3/5 volume of water to the quenched reaction to form a two-phase system, and harvesting the extracted product and internal standard from the upper phase; (f) purifying the reaction product and internal standard by passage of the extract from (e) through silica gel and washing the silica gel with a mixture of ethyl acetate/MeOH; and (g) quantifying the product and the internal standard to determine the acid glucosidase activity. (a) extracting acid glucosidase from a dried blood spot obtained from the subject using an aqueous buffer solution; (b) adding an assay mix comprising substrate, an internal standard, detergent, buffer and acarbose to the extracted acid glucosidase, wherein the molar ratio of substrate to internal standard is 100:1, the molar ratio of detergent to substrate is 24.3:1, the molar ratio of buffer to substrate is 450:1 and the molar ratio of acarbose to substrate is 0.02:1; (c) reacting the substrate with the extracted acid glucosidase; (d) quenching the reaction by addition of four volumes of a solution consisting essentially of ethyl acetate/methanol (1/1); (e) extracting the reaction product and internal standard by adding at least about a 3/5 volume of ethyl acetate and at least about a 3/5 volume of water to the quenched reaction to form a two-phase system, and harvesting the extracted product and internal standard from the upper phase; (f) purifying the reaction product and internal standard by passage of the extract from (e) through silica gel and washing the silica gel with a mixture of ethyl acetate/MeOH; and (g) quantifying the product and the internal standard to determine the acid glucosidase activity.
A self-clamping handrail device comprising: a belt-handrail compound comprising a belt (2; 3), and a handrail coupled to the belt (2; 3); a counter bar and a clamping frame configured to support the belt-handrail compound as the belt-handrail compound passes between the counter bar and the clamping frame; characterized in that the clamping frame is configured to move about a clamping curve based on a tension force applied to the handrail; and the belt (2, 3) is configured to apply a normal force to the handrail based at least in part on the tension force. a belt-handrail compound comprising a belt (2; 3), and a handrail coupled to the belt (2; 3); a counter bar and a clamping frame configured to support the belt-handrail compound as the belt-handrail compound passes between the counter bar and the clamping frame; characterized in that the clamping frame is configured to move about a clamping curve based on a tension force applied to the handrail; and the belt (2, 3) is configured to apply a normal force to the handrail based at least in part on the tension force.
A light emission device comprising a support having a central axis adapted to house a plurality of LED light emission devices arranged so as to direct the emitted light flow in a substantially radial direction with respect to said axis; a lens comprising a first inlet surface, facing the LEDs and inclined with respect to said axis by an angle α comprised from 0° to 45°; a second internal reflection surface having a curvature with the concavity facing downwards and covered, at least in part, by a reflector; a third outlet surface, substantially normal to said axis, adapted to emit the light flow exiting the lens, characterized in that the reflector and the lens are spaced apart from each other at least for a part of the extension thereof, so as to form a gap between said reflector and said lens. a support having a central axis adapted to house a plurality of LED light emission devices arranged so as to direct the emitted light flow in a substantially radial direction with respect to said axis; a lens comprising a first inlet surface, facing the LEDs and inclined with respect to said axis by an angle α comprised from 0° to 45°; a second internal reflection surface having a curvature with the concavity facing downwards and covered, at least in part, by a reflector; a third outlet surface, substantially normal to said axis, adapted to emit the light flow exiting the lens, characterized in that the reflector and the lens are spaced apart from each other at least for a part of the extension thereof, so as to form a gap between said reflector and said lens. a first inlet surface, facing the LEDs and inclined with respect to said axis by an angle α comprised from 0° to 45°; a second internal reflection surface having a curvature with the concavity facing downwards and covered, at least in part, by a reflector; a third outlet surface, substantially normal to said axis, adapted to emit the light flow exiting the lens, characterized in that the reflector and the lens are spaced apart from each other at least for a part of the extension thereof, so as to form a gap between said reflector and said lens.
An apparatus for the manufacturing of ultra-fine gas-bubbled water by resonance bubble-forming and vacuum cavitation, wherein the gas is selected from air, hydrogen, oxygen, ozone, nitrogen, carbon dioxide, and a mixture of nitrogen and carbon dioxide, the apparatus comprising: a conducting pipe adapted to let water being sucked from a water source run through; a primary pump adapted to suck the water and to jet it out; a gas supply device adapted to supply a gas and being selected from an air suction device, a hydrogen supply device, an oxygen supply device, an ozone supply device, and a supply device (34, 35) adapted to supply nitrogen gas, carbon dioxide gas, or a mixture of nitrogen gas and carbon dioxide gas; a resonance ejector comprising a resonance adjustment needle valve, a pressure gauge, a gas flowmeter, and a resonance bubble-forming device; a secondary pump having a suction force that is capable of sucking more volume of water than the volume of water discharged from the primary pump; a conducting pipe that is provided between the resonance bubble-forming device and the secondary pump; and a pressurizing device, wherein the apparatus is adapted to manufacture ultra-fine bubbles that contain one of the group consisting of oxidative radicals of air, reductive radicals of hydrogen, oxidative radicals of oxygen, ozone, nitrogen, carbon dioxide, and a mixture of nitrogen and carbon dioxide, respectively. a conducting pipe adapted to let water being sucked from a water source run through; a primary pump adapted to suck the water and to jet it out; a gas supply device adapted to supply a gas and being selected from an air suction device, a hydrogen supply device, an oxygen supply device, an ozone supply device, and a supply device (34, 35) adapted to supply nitrogen gas, carbon dioxide gas, or a mixture of nitrogen gas and carbon dioxide gas; a resonance ejector comprising a resonance adjustment needle valve, a pressure gauge, a gas flowmeter, and a resonance bubble-forming device; a secondary pump having a suction force that is capable of sucking more volume of water than the volume of water discharged from the primary pump; a conducting pipe that is provided between the resonance bubble-forming device and the secondary pump; and a pressurizing device, wherein the apparatus is adapted to manufacture ultra-fine bubbles that contain one of the group consisting of oxidative radicals of air, reductive radicals of hydrogen, oxidative radicals of oxygen, ozone, nitrogen, carbon dioxide, and a mixture of nitrogen and carbon dioxide, respectively.
An I/O module comprising: a first interface configured to connect one or more field devices; a second interface configured to connect a controller controlling the one or more field devices; a third interface configured to connect a setting device; a setting adjustor configured to connect the first interface with the second interface and the first interface with the third interface; and an interceptor configured to intercept the one or more field devices connected to the first interface from the setting device connected to the third interface, and to connect the one or more field devices connected to the first interface with the controller connected to the second interface, based on an instruction of the controller, and to intercept the one or more field devices connected to the first interface from the controller connected to the second interface, and to connect the setting device connected to the third interface with the one or more field devices connected to the first interface, based on the instruction of the setting device via the third interface. a first interface configured to connect one or more field devices; a second interface configured to connect a controller controlling the one or more field devices; a third interface configured to connect a setting device; a setting adjustor configured to connect the first interface with the second interface and the first interface with the third interface; and an interceptor configured to intercept the one or more field devices connected to the first interface from the setting device connected to the third interface, and to connect the one or more field devices connected to the first interface with the controller connected to the second interface, based on an instruction of the controller, and to intercept the one or more field devices connected to the first interface from the controller connected to the second interface, and to connect the setting device connected to the third interface with the one or more field devices connected to the first interface, based on the instruction of the setting device via the third interface.
An automatic pilot device for a rotary wing aircraft, comprising at least one automatic pilot assembly, each automatic pilot assembly comprising at least two primary actuators (24, 26, 28) configured to act on the aircraft, in which at least one or each of the primary actuators (24, 26, 28) incorporates an electronic computation unit configured to: - communicate with the measuring system onboard the aircraft configured to generate measuring signals representative of flight parameters of the aircraft, on the one hand, and/or a cockpit usable by a crew to pilot the aircraft and configured to generate control signals as a function of the actions by the crew, on the other hand, and - compute, as a function of the measuring signals and/or control signals, a piloting setpoint for the primary actuator (24, 26, 28) incorporating this computation unit and/or a piloting setpoint for at least one or each other primary actuator (24, 26, 28) of the automatic pilot assembly, for the piloting of the aircraft by the automatic pilot device. - communicate with the measuring system onboard the aircraft configured to generate measuring signals representative of flight parameters of the aircraft, on the one hand, and/or a cockpit usable by a crew to pilot the aircraft and configured to generate control signals as a function of the actions by the crew, on the other hand, and - compute, as a function of the measuring signals and/or control signals, a piloting setpoint for the primary actuator (24, 26, 28) incorporating this computation unit and/or a piloting setpoint for at least one or each other primary actuator (24, 26, 28) of the automatic pilot assembly, for the piloting of the aircraft by the automatic pilot device.
A continuously variable speed transmission comprising an electromotive device, the CVT having a longitudinal axis, a plurality of balls distributed radially about the longitudinal axis, each ball having an axle defining a tiltable axis about which it rotates; the CVT having an input disc in contact with the plurality of balls, an output disc in contact with the plurality of balls, an idler rotatable about the longitudinal axis and positioned radially inward of and in contact with the plurality of balls, a cage that is rotatable about the longitudinal axis and configured to position the plurality of balls radially and axially, and an idler shaft which is rigidly attached to the idler and is capable of axial movement, characterized in that the idler shaft transfers power; the input disc is configured to accept power from an outside source; an electric stator of the electromotive device is attached to the idler shaft; an electric rotor of the electromotive device comprises a plurality of magnets and is attached to the cage, wherein the electric rotor transfers power to the cage, and wherein the electric stator transfers power to the idler; and a set of wires is coupled to the electric stator for routing electric energy in and out of the CVT. the input disc is configured to accept power from an outside source; an electric stator of the electromotive device is attached to the idler shaft; an electric rotor of the electromotive device comprises a plurality of magnets and is attached to the cage, wherein the electric rotor transfers power to the cage, and wherein the electric stator transfers power to the idler; and a set of wires is coupled to the electric stator for routing electric energy in and out of the CVT.
A capsule for an electronic cigarette, the capsule having a first end for engaging with an electronic cigarette device and a second end configured as a mouthpiece portion having a vapor outlet, the capsule further comprising: - a liquid store configured to contain a liquid to be vaporized, - a vaporizing unit comprising a heater and a tubular fluid transfer element, the vaporizing unit being arranged within a vaporizing chamber, - a main vapor channel extending from the vaporizing chamber to the vapor outlet in the mouthpiece, and - a housing enclosing the liquid store and the vaporizing unit, wherein the fluid transfer element is fluidly connected to the liquid store by at least one liquid inlet which abuts an external surface of the tubular fluid transfer element and the fluid transfer element provides a capillary action on liquid received therein, wherein the heater is provided in contact with an internal surface of the tubular fluid transfer element and at a position that is substantially adjacent the liquid inlet, or at a position between the liquid inlet and the mouthpiece, wherein the housing comprises an inner housing and an outer housing that are assembled together, wherein the vaporizing chamber is located substantially within the inner housing and the liquid store is located in a void in-between the inner housing and the outer housing, and characterised in that the inner housing is provided with a flange that encircles an inner circumference of the tubular fluid transfer element to prevent the fluid transfer element collapsing into the vaporizing chamber. - a liquid store configured to contain a liquid to be vaporized, - a vaporizing unit comprising a heater and a tubular fluid transfer element, the vaporizing unit being arranged within a vaporizing chamber, - a main vapor channel extending from the vaporizing chamber to the vapor outlet in the mouthpiece, and - a housing enclosing the liquid store and the vaporizing unit,
A device capable of dynamically controlling sensitivity associated with detecting R-waves, the device comprising: a plurality of electrodes; a sense amplifier configured to be coupled to a pair of the electrodes and configured to output an analog signal indicative of cardiac electrical activity; an analog-to-digital converter configured to convert the analog signal indicative of cardiac electrical activity to a digital signal indicative of cardiac electrical activity; adjustable gain circuitry downstream of the ADC and configured to adjust a gain applied to the digital signal indicative of cardiac electrical activity; a comparator downstream of the adjustable gain circuitry and configured to detect R-waves by comparing the digital signal indicative of cardiac electrical activity to a fixed detection threshold to thereby detect threshold crossings that corresponds to R-waves; and a controller configured to selectively adjust the gain applied by the adjustable gain circuitry to thereby selectively adjust a sensitivity associated with the comparator detecting R-waves by detecting threshold crossings that corresponds to R-waves. a plurality of electrodes; a sense amplifier configured to be coupled to a pair of the electrodes and configured to output an analog signal indicative of cardiac electrical activity; an analog-to-digital converter configured to convert the analog signal indicative of cardiac electrical activity to a digital signal indicative of cardiac electrical activity; adjustable gain circuitry downstream of the ADC and configured to adjust a gain applied to the digital signal indicative of cardiac electrical activity; a comparator downstream of the adjustable gain circuitry and configured to detect R-waves by comparing the digital signal indicative of cardiac electrical activity to a fixed detection threshold to thereby detect threshold crossings that corresponds to R-waves; and a controller configured to selectively adjust the gain applied by the adjustable gain circuitry to thereby selectively adjust a sensitivity associated with the comparator detecting R-waves by detecting threshold crossings that corresponds to R-waves.