mhurhangee/ep-ind-claims huggingface dataset:
A compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein: Cy 1 is a group of Formula Cy 1 -A or Cy 1 -B: R 1, R 2, R 3, and R 4 are each independently selected from H and C 1-4 alkyl; or R 2 and R 4 are combined to form a bridging -CH 2 - or -CH 2 CH 2 - group; R 5 is -C(=O)R 5a; R 5a is C 1-4 alkyl, C 1-4 haloalkyl, C 1-4 hydroxyalkyl, (C 1-4 alkoxy)-C 1-4 alkyl-, C 3-6 cycloalkyl, or C 3-6 cycloalkyl-C 1-4 alkyl-; R 5b is H or C 1-4 alkyl; R 6 is H or methyl; R 7 is H, C 1-4 alkyl, -C(=O)R 7a, -C(=O)OR 7a, -C(=O)NR 7a R 7b, -S(=O) 2 R 7a, or -S(=O) 2 NR 7a R7 7b; R 7a is C 1-4 alkyl, C 1-4 haloalkyl, C 1-4 hydroxyalkyl, (C 1-4 alkoxy)-C 1-4 alkyl-, C 3-6 cycloalkyl, or C 3-6 cycloalkyl-C 1-4 alkyl-; R 7b is H or C 1-4 alkyl; R 8 is H or methyl; Cy 2 is pyridin-2-yl or pyridin-3-yl, each of which is optionally substituted by F or Cl, wherein said F and Cl are meta or para to the pyridine nitrogen; R 9 is H, F, or CH 2 OH; and R 10 is H, -C(=O)NHCH 3, -C(=O)NHCH 2 CH 3, -C(=O)NHCH 2 CH 2 CH 3, or -C(=O)NHCH(CH 3) 2; provided: i) when R 5a is methyl, ethyl or i-propyl, then one of R 1, R 2, R 3, and R 4 is other than H; ii) when R 7a is methyl, ethyl, i-propyl, -CF 3, or methoxymethyl, then one of R 1, R 2, R 3, and R 4 is other than H; and iii) when R 7 and R 8 are both methyl, then one of R 1, R 2, R 3, and R 4 is other than H. Cy 1 is a group of Formula Cy 1 -A or Cy 1 -B: R 1, R 2, R 3, and R 4 are each independently selected from H and C 1-4 alkyl; or R 2 and R 4 are combined to form a bridging -CH 2 - or -CH 2 CH 2 - group; R 5 is -C(=O)R 5a; R 5a is C 1-4 alkyl, C 1-4 haloalkyl, C 1-4 hydroxyalkyl, (C 1-4 alkoxy)-C 1-4 alkyl-, C 3-6 cycloalkyl, or C 3-6 cycloalkyl-C 1-4 alkyl-; R 5b is H or C 1-4 alkyl; R 6 is H or methyl; R 7 is H, C 1-4 alkyl, -C(=O)R 7a, -C(=O)OR 7a, -C(=O)NR 7a R 7b, -S(=O) 2 R 7a, or -S(=O) 2 NR 7a R7 7b; R 7a is C 1-4 alkyl, C 1-4 haloalkyl, C 1-4 hydroxyalkyl, (C 1-4 alkoxy)-C 1-4 alkyl-, C 3-6 cycloalkyl, or C 3-6 cycloalkyl-C 1-4 alkyl-; R 7b is H or C 1-4 alkyl; R 8 is H or methyl; Cy 2 is pyridin-2-yl or pyridin-3-yl, each of which is optionally substituted by F or Cl, wherein said F and Cl are meta or para to the pyridine nitrogen; R 9 is H, F, or CH 2 OH; and R 10 is H, -C(=O)NHCH 3, -C(=O)NHCH 2 CH 3, -C(=O)NHCH 2 CH 2 CH 3, or -C(=O)NHCH(CH 3) 2; i) when R 5a is methyl, ethyl or i-propyl, then one of R 1, R 2, R 3, and R 4 is other than H; ii) when R 7a is methyl, ethyl, i-propyl, -CF 3, or methoxymethyl, then one of R 1, R 2, R 3, and R 4 is other than H; and iii) when R 7 and R 8 are both methyl, then one of R 1, R 2, R 3, and R 4 is other than H.
An air conditioner comprising: a filter; a filter cleaning unit having a space formed therein for receiving foreign matter separated from the filter therein; a moving mechanism configured to move the filter cleaning unit along the filter, wherein the moving mechanism includes; a first gear a second gear engaged with the first gear, and a drive source for making the second gear to rotate, wherein the first gear has a closed loop section shape with gear teeth formed on at least one of the outside circumference and the inside circumference thereof, and the moving mechanism further includes: a gear guide for guiding the first gear during its movement, the gear guide being configured to maintain at least one linear portion (51, 52) of the first gear, a third gear engaged with a linear portion (51, 52) of the first gear, and a connection mechanism connected both to the third gear and the filter cleaning unit for making the filter cleaning unit to move, characterized in that the gear guide includes an inner guide positioned on an inside of the first gear, and an outer guide for surrounding the outside circumference of the first gear. a filter; a filter cleaning unit having a space formed therein for receiving foreign matter separated from the filter therein; a moving mechanism configured to move the filter cleaning unit along the filter, wherein the moving mechanism includes; a first gear a second gear engaged with the first gear, and a drive source for making the second gear to rotate, wherein the first gear has a closed loop section shape with gear teeth formed on at least one of the outside circumference and the inside circumference thereof, and the moving mechanism further includes: a gear guide for guiding the first gear during its movement, the gear guide being configured to maintain at least one linear portion (51, 52) of the first gear, a third gear engaged with a linear portion (51, 52) of the first gear, and a connection mechanism connected both to the third gear and the filter cleaning unit for making the filter cleaning unit to move, characterized in that the gear guide includes an inner guide positioned on an inside of the first gear, and an outer guide for surrounding the outside circumference of the first gear. a gear guide for guiding the first gear during its movement, the gear guide being configured to maintain at least one linear portion (51, 52) of the first gear, a third gear engaged with a linear portion (51, 52) of the first gear, and a connection mechanism connected both to the third gear and the filter cleaning unit for making the filter cleaning unit to move, characterized in that the gear guide includes an inner guide positioned on an inside of the first gear, and an outer guide for surrounding the outside circumference of the first gear.
A method for determining a zero-day attack by an electronic device, comprising: instantiating, by the electronic device, at least one virtual machine including a first virtual machine being based on a first software profile and a second virtual machine being based on a fortified software profile, the fortified software profile corresponding to a second software profile that is an updated version of the first software profile to address known exploits; concurrently processing copies of content associated with an exploit on both the first virtual machine and the second virtual machine; determining that the exploit corresponds to a zero-day exploit corresponding to a previously unseen type of malware when a second copy of the content, upon being processed on the second virtual machine, causes the second virtual machine to detect one or more behaviors each assigned a weight based on a likelihood of causing system compromise, wherein a weighted value of the one or more behaviors exceeds a predetermined threshold; and determining that the exploit is attacking a known vulnerability of the first software profile when (i) the weighted value of the one or more behaviors detected during processing of the second copy of the content in the second virtual machine is less than the predetermined threshold and (ii) a weighted value of one or more behaviors detected in the first virtual machine exceeds the predetermined threshold. instantiating, by the electronic device, at least one virtual machine including a first virtual machine being based on a first software profile and a second virtual machine being based on a fortified software profile, the fortified software profile corresponding to a second software profile that is an updated version of the first software profile to address known exploits; concurrently processing copies of content associated with an exploit on both the first virtual machine and the second virtual machine; determining that the exploit corresponds to a zero-day exploit corresponding to a previously unseen type of malware when a second copy of the content, upon being processed on the second virtual machine, causes the second virtual machine to detect one or more behaviors each assigned a weight based on a likelihood of causing system compromise, wherein a weighted value of the one or more behaviors exceeds a predetermined threshold; and determining that the exploit is attacking a known vulnerability of the first software profile when (i) the weighted value of the one or more behaviors detected during processing of the second copy of the content in the second virtual machine is less than the predetermined threshold and (ii) a weighted value of one or more behaviors detected in the first virtual machine exceeds the predetermined threshold.
Method for controlling at least one triggering element (ZP, LEA) for a personal protective means with a high-side control circuit which establishes a first connection from an energy source to the at least one triggering element (ZP, LEA), a low-side control circuit which establishes a second connection from the at least one triggering element (ZP, LEA) to earth, and a regulating arrangement for regulating a firing current (I ZP, I LEA) for the at least one triggering element (ZP, LEA), characterized in that a plurality of firing modes are provided, one firing mode of which is selected on the basis of a connected triggering element (ZP, LEA), a first firing current (I ZP) having a first temporal profile for a substantially resistive triggering element being generated in a first firing mode and a second firing current (I LEA) having a second temporal profile for a substantially inductive triggering element being generated in a second firing mode, a current monitoring function being carried out and generating at least one control signal (S 1, S 2) which temporally limits the output firing current (I ZP, I LEA) on the basis of the current firing mode.
Cosmetic product for modifying the natural colour of keratinous fibres, in particular human hair, comprising (i) at least one package comprising at least one multilayer film comprising at least one first polymer layer, at least one second polymer layer and at least one barrier layer, and (ii) at least one cosmetic composition packaged in the packaging and containing: a) at least one oxidising compound and b) at least one thickening agent selected from the group of xanthans, characterised in that the first polymer layer is formed of polyethylene terephthalate; the second polymer layer is formed of polyethylene; and the barrier layer is formed of a polyethylene terephthalate provided with an SiO x layer. (i) at least one package comprising at least one multilayer film comprising at least one first polymer layer, at least one second polymer layer and at least one barrier layer, and (ii) at least one cosmetic composition packaged in the packaging and containing: a) at least one oxidising compound and b) at least one thickening agent selected from the group of xanthans, a) at least one oxidising compound and b) at least one thickening agent selected from the group of xanthans,
A method of generating synchronized media from digital input data with a first plurality of channels, comprising: determining the same first plurality of thresholds, one for each of the channels; identifying a second plurality of control points indexed in chronological order within each channel, excluding the beginning point of the channel; wherein the content at any control point within a channel is to be synchronized with the content at the control point with the same index within each of the other channels; using each channel's control points to partition the channel into the same second plurality of piecewise segments so that each segment starts and ends at a control point except for the first segment, which starts at the beginning point of the channel and ends at the first control point; applying a first algorithm to determine the same second plurality of target lengths, one for all segments with the same index across all channels, as well as a set of parameters for each segment; applying a second algorithm to modify the data of each segment to match the target length, using the respective set of parameters; regenerating each channel by joining the modified segments in the chronological order; wherein the content at each control point within any channel occurs at the same time as that across all other channels during media playback; wherein the content anywhere within all channels is perceived to be synchronized; wherein the perceived quality difference between the modified and original channels is below the threshold determined for the channel. determining the same first plurality of thresholds, one for each of the channels; identifying a second plurality of control points indexed in chronological order within each channel, excluding the beginning point of the channel; wherein the content at any control point within a channel is to be synchronized with the content at the control point with the same index within each of the other channels; using each channel's control points to partition the channel into the same second plurality of piecewise segments so that each segment starts and ends at a control point except for the first segment, which starts at the beginning point of the channel and ends at the first control point; applying a first algorithm to determine the same second plurality of target lengths, one for all segments with the same index across all channels, as well as a set of parameters for each segment; applying a second algorithm to modify the data of each segment to match the target length, using the respective set of parameters; regenerating each channel by joining the modified segments in the chronological order; wherein the content at each control point within any channel occurs at the same time as that across all other channels during media playback; wherein the content anywhere within all channels is perceived to be synchronized; wherein the perceived quality difference between the modified and original channels is below the threshold determined for the channel.
Use of a damaged hair improving agent comprising, as a main component, one or more selected from L-ascorbic acid derivatives represented by the following general formula and salts thereof: wherein R 1 is each independently a linear or branched saturated or unsaturated fatty acid residue having 8 to 36 carbon atoms, R 2 is a linear or branched saturated or unsaturated fatty acid residue having 8 to 36 carbon atoms, R 3 is a linear or branched saturated or unsaturated fatty acid residue having 8 to 36 carbon atoms wherein this derivative is present in an amount of from 0.5 to 20% by mass; for increasing the hydrophobicity of the hair surface and/or making hair smooth and/or further enhancing glossiness. wherein R 1 is each independently a linear or branched saturated or unsaturated fatty acid residue having 8 to 36 carbon atoms, R 2 is a linear or branched saturated or unsaturated fatty acid residue having 8 to 36 carbon atoms, R 3 is a linear or branched saturated or unsaturated fatty acid residue having 8 to 36 carbon atoms wherein this derivative is present in an amount of from 0.5 to 20% by mass; for increasing the hydrophobicity of the hair surface and/or making hair smooth and/or further enhancing glossiness.
A method for bonding fuselage, characterized by comprising the steps of: scooping a trunk section supported by a dolly with a strongback (8-i) according to any one of claims 4 to 7; disposing the trunk section at a predetermined position by displacing the strongback (8-i) using a positioner (7-m); and bonding the trunk section to a reference fuselage upon the trunk section being disposed at the predetermined position. scooping a trunk section supported by a dolly with a strongback (8-i) according to any one of claims 4 to 7; disposing the trunk section at a predetermined position by displacing the strongback (8-i) using a positioner (7-m); and bonding the trunk section to a reference fuselage upon the trunk section being disposed at the predetermined position.
Device for fixing to the internal wall of a tyre, an electronic box for measuring parameters inside the tyre, said box being preformed with an orifice making its internal space communicate with the internal space of the tyre, the device comprising said box and a flexible receptacle that is fixed to said internal wall by adhesion means is preformed to accept and retain said box, said flexible receptacle forming a compartment equipped with an opening, through which said box is introduced and which is bordered by an edge extending externally and offering a contact surface for the adhesion means, so that, once the receptacle is fixed, said opening is closed by the internal wall to which the receptacle is fixed, said opening being equipped with another edge referred to as the internal edge which, extending internally, creates a narrowing for the purpose of retaining the box in said compartment and a brace defining a space between the box and the internal wall of the tyre, characterised by the fact that said box is oriented in said compartment so that its orifice opens onto said space, and said box and/or said receptacle are preformed with passages making the space created inside the compartment communicate with the inside of the tyre.
Method of processing a continuously cast material, wherein the material after continuous casting in a continuous casting plant is divided into individual units, in particular slabs, wherein the units are brought into a storage place and after a storage time are transported from the storage place to processing or treatment equipment and processed or treated there, wherein detection of the temperature or temperature distribution is carried out for at least a number of units at at least one location, wherein a thermal substitute model is provided for the unit in a computer and the detected temperature or temperature distribution at the at least one location is supplied to the substitute model as a boundary condition for the unit, wherein the further temperature plot of the unit is computed by way of the thermal substitute model at least for a time segment and this is the basis for the subsequent processing or treatment of the unit, characterised in that the determination of the temperature or the temperature distribution is carried out by means of at least one pyrometer, by means of at least one heat scanner and/or by means of at least one thermal imaging camera, wherein the detection of the temperature or the temperature distribution is carried out during movement of the unit in that the pyrometer, heat scanner and/or thermal imaging camera is or are arranged at a mobile element for handling or transport of the unit.
A device for sealing and cutting a film in a packaging apparatus, comprising: a first member; a second member; wherein - the first member is movable with respect to the second member, or - the second member is movable with respect to the first member, or - both the first and second members are movable with respect to each other; wherein one of the first and second members comprises an elongated blade; one of the first and second members comprises a cutting means; characterized in that the cutting means are positionable in a plurality of positions with respect to the respective member (31, 32). a first member; a second member; - the first member is movable with respect to the second member, or - the second member is movable with respect to the first member, or - both the first and second members are movable with respect to each other; wherein one of the first and second members comprises an elongated blade; one of the first and second members comprises a cutting means;
A semiconductor magnetic field sensor comprising: - a semiconductor well (PW; NW) on top of a substrate layer, comprising: - a first current collecting region (20;22;23;24) and a second current collecting region (25;27;28;29), and - a current emitting region (15;16;17;18) placed between the first current collecting region (20;22;23;24) and the second current collecting region (25;27;28;29), - a first MOS structure, having a first gate terminal (G 1), located between the first current collecting region (20;22;23;24) and the current emitting region (15;16;17;18), - a second MOS structure, having a second gate terminal (G 2), located between the current emitting region (15;16;17;18) and the second current collecting region (25;27;28;29), - an insulation layer between the substrate layer and the semiconductor well (PW;NW), and - a semiconductor layer (NWD;PWD) between the semiconductor well (PW;NW) and the insulation layer, wherein, in operation, the first gate terminal (G 1) and the second gate terminal (G 2) are biased for increasing a deflection length (L eff) of a first current and of a second current, wherein the deflection length (L eff) is normal to the substrate surface and parallel to a magnetic field (B x), wherein the first and second currents flow in the semiconductor well (PW;NW) from the current emitting region (15;16;17;18) to the first current collecting region (20;22;23;24) and the second current collecting region (25;27;28;29), and wherein a difference between the first current and the second current is dependent on the magnetic field (B x) and wherein the semiconductor layer (NWD;PWD) is contacted by means of a first heavily doped contact region to a first terminal (T NW1) and by means of a second heavily doped contact region to a second terminal (T NW2). - a semiconductor well (PW; NW) on top of a substrate layer, comprising: - a first current collecting region (20;22;23;24) and a second current collecting region (25;27;28;29), and - a current emitting region (15;16;17;18) placed between the first current collecting region (20;22;23;24) and the second current collecting region (25;27;28;29), - a first MOS structure, having a first gate terminal (G 1), located between the first current collecting region (20;22;23;24) and the current emitting region (15;16;17;18), - a second MOS structure, having a second gate terminal (G 2), located between the current emitting region (15;16;17;18) and the second current collecting region (25;27;28;29), - an insulation layer between the substrate layer and the semiconductor well (PW;NW), and - a semiconductor layer (NWD;PWD) between the semiconductor well (PW;NW) and the insulation layer,
A multispecific antibody or fragment thereof that specifically binds: a. a first target epitope, wherein the first target epitope is an epitope of the variable delta 1 (Vδ1) chain of a γδ T cell receptor; and b. a second target epitope, wherein the second epitope is 4-1BB. a. a first target epitope, wherein the first target epitope is an epitope of the variable delta 1 (Vδ1) chain of a γδ T cell receptor; and b. a second target epitope, wherein the second epitope is 4-1BB.