mhurhangee/ep-ind-claims huggingface dataset:
A system comprising at least one contactless readable data carrier which can be mounted on a wheel of a vehicle and a reader which can be arranged on the vehicle for receiving electromagnetic signals emitted by the data carrier, the reader being designed to determine the wheel revolutions from the field strength fluctuations of the electromagnetic signals received, where the reader has calculation means designed to calculate, from the revolutions and a wheel periphery reference value that is allocated to the wheel and can be determined by the reader, such as the circumference, diameter or radius, a distance covered by a point on the wheel periphery and/or values derivable therefrom such as the peripheral speed of the wheel, characterised in that the data carrier is designed to send a wheel periphery reference value of the allocated wheel as an electromagnetic signal and the reader is designed to extract the wheel periphery reference value from the electromagnetic signals received from the data carrier and provide this to the calculation means.
An isolated immunogen, comprising: a recombinant HIV-1 Env ectodomain trimer stabilized in a prefusion mature closed conformation by one or more amino acid substitutions compared to a native HIV-1 Env sequence; wherein the one or more amino acid substitutions comprise cysteine substitutions at HIV-1 Env positions 201 and 433 to introduce a non-natural disulfide bond between the cysteine substitutions, wherein the HIV-1 Env positions correspond to a HXB2 reference set forth as SEQ ID NO:1; the recombinant HIV-1 Env ectodomain trimer comprises three gp120-gp41 protomers comprising a gp120 polypeptide and a gp41 ectodomain; and the recombinant HIV-1 Env ectodomain trimer does not specifically bind to a CD4-induced antibody when incubated with a molar excess of sCD4, wherein the CD4-induced antibody is 17b mAb. a recombinant HIV-1 Env ectodomain trimer stabilized in a prefusion mature closed conformation by one or more amino acid substitutions compared to a native HIV-1 Env sequence; wherein the one or more amino acid substitutions comprise cysteine substitutions at HIV-1 Env positions 201 and 433 to introduce a non-natural disulfide bond between the cysteine substitutions, wherein the HIV-1 Env positions correspond to a HXB2 reference set forth as SEQ ID NO:1; the recombinant HIV-1 Env ectodomain trimer comprises three gp120-gp41 protomers comprising a gp120 polypeptide and a gp41 ectodomain; and the recombinant HIV-1 Env ectodomain trimer does not specifically bind to a CD4-induced antibody when incubated with a molar excess of sCD4, wherein the CD4-induced antibody is 17b mAb.
A medical article formed from a polyurethane-based resin, which is a reaction product of the following ingredients: a diisocyanate; a diol chain extender; a polyglycol; and a modifying oligomer incorporated into a backbone of the polyurethane-based resin formed by the diisocyanate, the polyglycol, and the diol chain extender, the modifying oligomer being a diol-containing perfluoropolyether having the following structure HO(CH 2 CH 2 O) p CH 2 CF 2 O(CF 2 CF 2 O) q (CF 2 O) r CF 2 CH 2 (OCH 2 CH 2) p OH wherein the total of p+q+r is such that the fluorine content of the modifying oligomer is in the range of 55% to 60% by weight and the average molecular weight of the modifying oligomer is in the range of 1500 to 2200 g/mol; wherein a hard segment content is in the range of from 25% to 75% by weight and a soft segment content of the resin is in the range of from 75% to 25% by weight; and wherein a concentration of the modifying oligomer of the polyurethane-based resin at a surface of the medical article is higher than a theoretical concentration based on uniform distribution of ingredients of the polyurethane-based resin, and the medical article is effective as a self-lubricating and/or self-anti-fouling medical article. a diisocyanate; a diol chain extender; a polyglycol; and a modifying oligomer incorporated into a backbone of the polyurethane-based resin formed by the diisocyanate, the polyglycol, and the diol chain extender, the modifying oligomer being a diol-containing perfluoropolyether having the following structure HO(CH 2 CH 2 O) p CH 2 CF 2 O(CF 2 CF 2 O) q (CF 2 O) r CF 2 CH 2 (OCH 2 CH 2) p OH wherein the total of p+q+r is such that the fluorine content of the modifying oligomer is in the range of 55% to 60% by weight and the average molecular weight of the modifying oligomer is in the range of 1500 to 2200 g/mol; wherein a hard segment content is in the range of from 25% to 75% by weight and a soft segment content of the resin is in the range of from 75% to 25% by weight; and wherein a concentration of the modifying oligomer of the polyurethane-based resin at a surface of the medical article is higher than a theoretical concentration based on uniform distribution of ingredients of the polyurethane-based resin, and the medical article is effective as a self-lubricating and/or self-anti-fouling medical article.
Method for fitting a horseshoe in which the horseshoe having a top surface comprises at least one toe clip, the toe clip comprising an inclined inner surface forming a first acute angle (α1) with the top surface of said shoe, the toe clip is displaced to open the angle formed between said inner surface and said top surface, such that, after opening, a second angle (α2) formed by the inner surface of the toe clip and the top surface of the shoe is strictly between the first angle (α1) and 90°, to place the toe clip in contact with or in proximity to the hoof of the horse so that the latter forms an abutment, characterized in that said toe clip is produced in a thermoplastic material, said at least one toe clip is previously heated to a temperature allowing displacement of the corresponding toe clip.
Mixing system, in particular a bioreactor and/or a pallet tank, for mixing a fluid and/or a solid, comprising: - a container, wherein the fluid and/or the solid and a rotatable stirring element for mixing the fluid and/or the solid are arranged in the interior of the container, and - a mixing device comprising a holder for receiving the container and a drive device for driving the stirring element, wherein - the stirring element comprises a stirring shaft and/or is designed as a stirring shaft, wherein the stirring shaft runs all the way through the container from a first end of the container to a second end of the container, characterized in that - the drive device comprises a stator of a three-phase machine, - the stirring element comprises a rotor of the three-phase machine, - the rotor comprises at least one permanent magnet and/or at least one squirrel-cage rotor. - a container, wherein the fluid and/or the solid and a rotatable stirring element for mixing the fluid and/or the solid are arranged in the interior of the container, and - a mixing device comprising a holder for receiving the container and a drive device for driving the stirring element, - the stirring element comprises a stirring shaft and/or is designed as a stirring shaft, wherein the stirring shaft runs all the way through the container from a first end of the container to a second end of the container, characterized in that - the drive device comprises a stator of a three-phase machine, - the stirring element comprises a rotor of the three-phase machine, - the rotor comprises at least one permanent magnet and/or at least one squirrel-cage rotor.
A stapling assembly for use with a surgical stapler, comprising: a body having a plurality of staples disposed therein, the plurality of staples being configured to be deployed into tissue, and the body having a first end, a second end, and a longitudinal axis extending therebetween; and a three-dimensional compressible adjunct formed from a matrix comprising at least one fused bioabsorbable polymer and configured to be releasably retained on the body such that the adjunct can be attached to tissue by the plurality of staples in the body, the adjunct having a tissue-contacting layer, an opposite body-contacting layer, and a plurality of interconnected struts disposed between the tissue-contacting layer and the body-contacting layer, the interconnected struts being deformable to allow the tissue-contacting layer and the body-contacting layer to compress toward one another, and the tissue-contacting layer including a plurality of surface features defined therein such that, when the adjunct is stapled to tissue and the tissue is compressed into the tissue-contacting layer, the plurality of surface features substantially prevent slidable movement of the adjunct relative to the tissue; wherein at least a portion of the plurality of surface features comprises a plurality of ridges and a plurality of grooves defined between the plurality of ridges. a body having a plurality of staples disposed therein, the plurality of staples being configured to be deployed into tissue, and the body having a first end, a second end, and a longitudinal axis extending therebetween; and a three-dimensional compressible adjunct formed from a matrix comprising at least one fused bioabsorbable polymer and configured to be releasably retained on the body such that the adjunct can be attached to tissue by the plurality of staples in the body, the adjunct having a tissue-contacting layer, an opposite body-contacting layer, and a plurality of interconnected struts disposed between the tissue-contacting layer and the body-contacting layer, the interconnected struts being deformable to allow the tissue-contacting layer and the body-contacting layer to compress toward one another, and the tissue-contacting layer including a plurality of surface features defined therein such that, when the adjunct is stapled to tissue and the tissue is compressed into the tissue-contacting layer, the plurality of surface features substantially prevent slidable movement of the adjunct relative to the tissue; wherein at least a portion of the plurality of surface features comprises a plurality of ridges and a plurality of grooves defined between the plurality of ridges.
A reciprocating stirring apparatus having a micro bubble generating device, comprising: a stirring container into which an article to be stirred is inserted; and a driving shaft provided in the stirring container and performing a reciprocating motion; a stirring blade connected/fixed so as to cross the driving shaft; and the micro bubble generating device, wherein the micro bubble generating device includes a sparger formed of a porous body and gas supply means for supplying gas to the sparger; and wherein the porous body provides pores through which the gas supplied by the gas supply means to the sparger is let with generating bubbles into the article to be stirred, characterized in that the stirring blade has a rectangular, an elliptic or an oval shape made of a long diameter and a short diameter, and in that the sparger is tubular and extending in an axial direction of the driving shaft lateral to the driving shaft so that the sparger is provided on an outside of the long diameter of the stirring blade, supplying the gas lateral to the driving shaft with the stirring blade. a stirring container into which an article to be stirred is inserted; and a driving shaft provided in the stirring container and performing a reciprocating motion; a stirring blade connected/fixed so as to cross the driving shaft; and the micro bubble generating device, wherein the micro bubble generating device includes a sparger formed of a porous body and gas supply means for supplying gas to the sparger; and wherein the porous body provides pores through which the gas supplied by the gas supply means to the sparger is let with generating bubbles into the article to be stirred, characterized in that the stirring blade has a rectangular, an elliptic or an oval shape made of a long diameter and a short diameter, and in that the sparger is tubular and extending in an axial direction of the driving shaft lateral to the driving shaft so that the sparger is provided on an outside of the long diameter of the stirring blade, supplying the gas lateral to the driving shaft with the stirring blade.
An antibody or an antigen-binding fragment thereof with multivalent binding specificity for CD40, wherein the antibody or fragment comprises a variable light chain (V L) in which CDR1 comprises or consists of the amino acid sequence: CTGSX 1 SNIGAGYX 2 VY [SEQ ID NO:1] wherein: X 1 is S or T; and X 2 is K or H or D or G or N wherein the antibody or fragment comprises a variable light chain (V L) in which CDR2 comprises or consists of the amino acid sequence: X 3 NINRPS [SEQ ID NO:2] wherein: X 3 is G or R wherein the antibody or fragment a variable light chain (V L) in which CDR3 comprises or consists of the amino acid sequence: CAAWDX 4 X 5 X 6 X 7 GLX 8 [SEQ ID NO:3] wherein: X 4 is D or S or E or G or K; and X 5 is S or T or G; and X 6 is L or S or T or L or I; and X 7 is S or T or L; and X 8 is V or L wherein the antibody or fragment comprises a variable heavy chain (V H) in which CDR1 comprises or consists of the amino acid sequence of: GFTFSTYGMH [SEQ ID NO:28] wherein the antibody or fragment comprises a variable heavy chain (V H) in which CDR2 comprises or consists of the amino acid sequence of: GKGLEWLSYISGGSSYIFYADSVRGR [SEQ ID NO:29] wherein the antibody or fragment comprises a variable heavy chain (V H) in which CDR3 comprises or consists of the amino acid sequence of: CARILRGGSGMDL [SEQ ID NO:30] wherein the potency of the antibody or antigen-binding fragment for dendritic cell activation is higher than, or is equal to, its potency for B cell activation and wherein the antibody or antigen-binding fragment has an affinity for CD40 of less than 1x10 -10 M wherein the antibody or an antigen-binding fragment thereof are capable of binding to domain 1 of CD40 and wherein the affinity for CD40 is measured by surface plasmon resonance. CTGSX 1 SNIGAGYX 2 VY [SEQ ID NO:1] X 1 is S or T; and X 2 is K or H or D or G or N X 3 NINRPS [SEQ ID NO:2] X 3 is G or R CAAWDX 4 X 5 X 6 X 7 GLX 8 [SEQ ID NO:3] X 4 is D or S or E or G or K; and X 5 is S or T or G; and X 6 is L or S or T or L or I; and X 7 is S or T or L; and X 8 is V or L GFTFSTYGMH [SEQ ID NO:28] GKGLEWLSYISGGSSYIFYADSVRGR [SEQ ID NO:29] CARILRGGSGMDL [SEQ ID NO:30]
A compound, the compound consisting of the (+) isomer of formula: wherein: R 1 is hydrogen or methyl; and L 3 is a linker of 10 contiguous atoms attached to the benzene ring at the meta position, the atoms being selected from the group consisting of an atom of a hydrocarbyl, an atom of a substituted hydrocarbyl, and a heteroatom. R 1 is hydrogen or methyl; and L 3 is a linker of 10 contiguous atoms attached to the benzene ring at the meta position, the atoms being selected from the group consisting of an atom of a hydrocarbyl, an atom of a substituted hydrocarbyl, and a heteroatom.
A method of performing point on wave switching in a multiphase electrical system having a first circuit breaker connected to a first bus, the first circuit breaker operated by a first controller, a second circuit breaker connected to a second bus, the second circuit breaker operated by a second controller, and a subsystem transferred from the first bus to the second bus, the method comprising: a. receiving, by the second controller, system characteristics data of the subsystem; characterized in that the method further comprises: b. estimating, by the second controller, a time for switching based on the received system characteristics data of the subsystem and operating time of the second circuit breaker; c. operating, by the second controller, the second circuit breaker at the estimated time for switching, for switching the subsystem, wherein the system characteristics data is transmitted from one or more subsystem data sources, upon receiving a signal from at least one of an isolator (131, 169, 191, 199) connected between the circuit breaker and the bus and an operator, and wherein the one or more subsystem data sources includes the first controller. a. receiving, by the second controller, system characteristics data of the subsystem; b. estimating, by the second controller, a time for switching based on the received system characteristics data of the subsystem and operating time of the second circuit breaker; c. operating, by the second controller, the second circuit breaker at the estimated time for switching, for switching the subsystem,
A device to be inserted into the aortic arch for deflecting emboli, the device comprising: a lateral structure defining a lateral plane comprising a first end and a second end to support an emboli filter, the lateral structure has a length and the emboli filter is attached to and extending the length of said lateral structure; a lower member (106, 108) extending downward from said lateral structure in a direction of an ascending aorta when inserted into the arch, wherein upon installation of said device, said lower member exerts lift on a middle area of said lateral structure; and an upper member extending upwards from said lateral structure extending into an innominate artery upon deployment, wherein a support portion of said upper member being proximate to said lateral structure rises away from said lateral structure at an angle towards the first end of said device, characterized in an anchor portion of said upper member being distal to said lateral structure double back on said support portion at a bend and rises upward and towards a direction of the second end of said device, wherein upon said installation, said upper member limits said lift. a lateral structure defining a lateral plane comprising a first end and a second end to support an emboli filter, the lateral structure has a length and the emboli filter is attached to and extending the length of said lateral structure; a lower member (106, 108) extending downward from said lateral structure in a direction of an ascending aorta when inserted into the arch, wherein upon installation of said device, said lower member exerts lift on a middle area of said lateral structure; and an upper member extending upwards from said lateral structure extending into an innominate artery upon deployment, wherein a support portion of said upper member being proximate to said lateral structure rises away from said lateral structure at an angle towards the first end of said device, characterized in an anchor portion of said upper member being distal to said lateral structure double back on said support portion at a bend and rises upward and towards a direction of the second end of said device, wherein upon said installation, said upper member limits said lift.
A biometric information process device comprising: a biometric sensor configured to obtain a plurality of biometric images of a user; a detection portion configured to detect a surface reflection region of the plurality of biometric images, the surface reflection being light reflecting at an interface between air and a biological body, wherein the detection portion is configured to detect the surface reflection region based on at least one of a brightness value being more than a brightness threshold and a high frequency wave component being more than a high frequency wave component threshold; a calculation portion configured to calculate an overlapping degree of surface reflection regions detected by the detection portion with respect to the plurality of biometric images; an induction portion configured to induce a change in at least one of a position of the biological body, a distance between the biological body and the biometric sensor, and an inclination of the biological body with respect to the biometric sensor, when the biometric sensor obtains biometric images and the overlapping degree calculated by the calculation portion is a predetermined value or more; and a storage portion configured to store biometric information obtained from biometric images included in the plurality of biometric images, when the overlapping degree calculated by the calculation portion is a predetermined value or less. a biometric sensor configured to obtain a plurality of biometric images of a user; a detection portion configured to detect a surface reflection region of the plurality of biometric images, the surface reflection being light reflecting at an interface between air and a biological body, wherein the detection portion is configured to detect the surface reflection region based on at least one of a brightness value being more than a brightness threshold and a high frequency wave component being more than a high frequency wave component threshold; a calculation portion configured to calculate an overlapping degree of surface reflection regions detected by the detection portion with respect to the plurality of biometric images; an induction portion configured to induce a change in at least one of a position of the biological body, a distance between the biological body and the biometric sensor, and an inclination of the biological body with respect to the biometric sensor, when the biometric sensor obtains biometric images and the overlapping degree calculated by the calculation portion is a predetermined value or more; and a storage portion configured to store biometric information obtained from biometric images included in the plurality of biometric images, when the overlapping degree calculated by the calculation portion is a predetermined value or less.
Device for testing and refurbishing a switch mechanism for a railway switch, with a test rig for the mechanical and electrical testing of the functional capability of the actuating mechanism according to predeterminable test instructions, characterized in that the test rig is arranged and can be operated in a transportable and walk-in large-capacity container, the large-capacity container having a test area, in which the test rig is arranged, and, away from it, a workshop area for the refurbishing of a switch mechanism and the large-capacity container having a voltage adjustment module, in order to convert the supply voltage respectively on the primary side into an operating voltage on the secondary side for the device in countries with different national power supply systems.
An electromagnetic angle sensor having a stator and a rotor (120, 120a-120b), the rotor (120, 120a-120b) being rotatably supported along a rotation axis on the stator and separated therefrom by a gap, the stator having at least one magnetic field generating means adapted to generate a distribution of magnetic flux that extends over the gap, and at least one magnetic field detecting means adapted to detect a change in the magnetic flux distribution caused by a rotation of the rotor, the electromagnetic angle sensor comprising: a magnetic flux enhancer adapted to concentrate the generated distribution of magnetic flux over the gap along a radial direction substantially perpendicular to the rotation axis; the stator comprising at least one protrusion along the radial direction for arranging said at least one magnetic field generating means and said magnetic flux enhancer, characterized in that the magnetic flux enhancer is a magnetic clip adapted to be snapped into said protrusion and positioned on the side of the magnetic field generating means that faces the rotor so as to concentrate the distribution of generated magnetic flux over the gap along said radial direction. a magnetic flux enhancer adapted to concentrate the generated distribution of magnetic flux over the gap along a radial direction substantially perpendicular to the rotation axis; the stator comprising at least one protrusion along the radial direction for arranging said at least one magnetic field generating means and said magnetic flux enhancer, characterized in that the magnetic flux enhancer is a magnetic clip adapted to be snapped into said protrusion and positioned on the side of the magnetic field generating means that faces the rotor so as to concentrate the distribution of generated magnetic flux over the gap along said radial direction.