mhurhangee/ep-ind-claims huggingface dataset:
A recombinant cell prepared by introducing (i) genes encoding at least the enzyme or the enzymes selected from the groups to consisting of: CoA-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase; or 2-oxoglutarate decarboxylase; and introducing (iia) the genes encoding at least the enzymes consisting of: 4-hydroxybutyrate dehydrogenase, 4-hydroxybutyryl-CoA transferase, 4-hydroxybutyryl-CoA reductase, and alcohol dehydrogenase; or (iib) the genes encoding at least the enzymes consisting of 4-hydroxybutyrate dehydrogenase, 4-hydroxybutyraldehyde dehydrogenase, and alcohol dehydrogenase, into a host cell which is a methylotroph, wherein the methylotroph belongs to genus Pichia, genus Methylobacterium, or genus Methylophilus, the genes are expressed in the host cell, and the recombinant cell is capable of producing 1,4-butanediol from at least one C1 compound selected from the group consisting of methane, methanol, methylamine, formic acid, formaldehyde, and formamide. CoA-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase; or 2-oxoglutarate decarboxylase; 4-hydroxybutyrate dehydrogenase, 4-hydroxybutyryl-CoA transferase, 4-hydroxybutyryl-CoA reductase, and alcohol dehydrogenase; or (iib) the genes encoding at least the enzymes consisting of 4-hydroxybutyrate dehydrogenase, 4-hydroxybutyraldehyde dehydrogenase, and alcohol dehydrogenase, into a host cell which is a methylotroph, wherein the methylotroph belongs to genus Pichia, genus Methylobacterium, or genus Methylophilus, the genes are expressed in the host cell, and the recombinant cell is capable of producing 1,4-butanediol from at least one C1 compound selected from the group consisting of methane, methanol, methylamine, formic acid, formaldehyde, and formamide.
A medical fluid circuit, comprising: a batch container for a medical fluid; a fluid supply line connected to the batch container for supplying the medical fluid; an expansion chamber arranged along the supply line; a first sensor configured to send at least a first signal indicating an emptying of the batch container; a second sensor configured to send at least a second signal indicating a parameter in the expansion chamber,; and a control unit configured to perform a control procedure of a situation in the expansion chamber; characterized in that the parameter is one of a pressure in the expansion chamber and a liquid level in the expansion chamber, and in that the control procedure comprises following operations: ▪ detecting a situation of emptying of the batch container from the first signal; ▪ detecting at least a value of said parameter inside the expansion chamber during the emptying situation; ▪ performing a control on whether the at least a value of the parameter is in a determined relation with at least a reference value; ▪ recognising a faulty situation in the expansion chamber based on said control. a batch container for a medical fluid; a fluid supply line connected to the batch container for supplying the medical fluid; an expansion chamber arranged along the supply line; a first sensor configured to send at least a first signal indicating an emptying of the batch container; a second sensor configured to send at least a second signal indicating a parameter in the expansion chamber,; and a control unit configured to perform a control procedure of a situation in the expansion chamber; the parameter is one of a pressure in the expansion chamber and a liquid level in the expansion chamber, and in that the control procedure comprises following operations: ▪ detecting a situation of emptying of the batch container from the first signal; ▪ detecting at least a value of said parameter inside the expansion chamber during the emptying situation; ▪ performing a control on whether the at least a value of the parameter is in a determined relation with at least a reference value; ▪ recognising a faulty situation in the expansion chamber based on said control. ▪ detecting a situation of emptying of the batch container from the first signal; ▪ detecting at least a value of said parameter inside the expansion chamber during the emptying situation; ▪ performing a control on whether the at least a value of the parameter is in a determined relation with at least a reference value; ▪ recognising a faulty situation in the expansion chamber based on said control.
A method for managing virtual machines, comprising: obtaining (Step 400) a management request for a virtual machine of the virtual machines; in response to obtaining the management request: performing (Step 402) a remote resource analysis of the virtual machine to obtain an application profile of the virtual machine comprising one or more dimensions, each dimension representing a type of an application (612, 614) executing on the virtual machine; performing (Step 404) a multidimensional application analysis of the application profile to identify at least one tag; and applying (Step 406) the at least one tag to the virtual machine, storing backup/restoration policies in persistent storage wherein a first portion of the backup/restoration policies is keyed to a plurality of tags associated with the virtual machines. obtaining (Step 400) a management request for a virtual machine of the virtual machines; in response to obtaining the management request: performing (Step 402) a remote resource analysis of the virtual machine to obtain an application profile of the virtual machine comprising one or more dimensions, each dimension representing a type of an application (612, 614) executing on the virtual machine; performing (Step 404) a multidimensional application analysis of the application profile to identify at least one tag; and applying (Step 406) the at least one tag to the virtual machine, performing (Step 402) a remote resource analysis of the virtual machine to obtain an application profile of the virtual machine comprising one or more dimensions, each dimension representing a type of an application (612, 614) executing on the virtual machine; performing (Step 404) a multidimensional application analysis of the application profile to identify at least one tag; and applying (Step 406) the at least one tag to the virtual machine, storing backup/restoration policies in persistent storage wherein a first portion of the backup/restoration policies is keyed to a plurality of tags associated with the virtual machines.
Method for moving a manually movable tool to at least one predetermined operating position, wherein the tool, guided by guiding means (3, 4), is moved in a plane (X, Y) from a starting position into an intermediate position (28, 28), which is in line with the operating position, and, guided by further guiding means, is adjusted from the intermediate position (28, 28) into the operating position, wherein the position of the tool is measured while it is moving from the starting position into the intermediate position (28, 28) and, when a predetermined distance of the tool from the intermediate position in axial directions of the plane (X, Y) is detected, non-manual adjusting means (10, 20) are activated, and the adjusting means (10, 20) move the tool into the intermediate position.
Apparatus for use with a blood vessel of a subject, comprising: a stent configured to be placed in the blood vessel, the stent comprising: a generally cylindrical stent body; a plurality of posts protruding longitudinally from an end of the stent body; an antenna disposed annularly on the posts, such that the posts separate the antenna from the end of the stent body, characterized in that: the apparatus further comprises: a transmitter configured to transmit RF energy towards the antenna, such as to generate an inductive current through the antenna; an electrode coupled to the stent; and a control capsule coupled to the stent, the control capsule being configured to be powered using the inductive current of the antenna, and with the control capsule being configured to drive a current into the blood vessel, via the electrode; the posts are configured, by separating the antenna from the end of the stent body, to reduce a strength of the inductive current that is generated in the stent body, due to a magnetic field that is generated by the inductive current of the antenna. a stent configured to be placed in the blood vessel, the stent comprising: a generally cylindrical stent body; a plurality of posts protruding longitudinally from an end of the stent body; an antenna disposed annularly on the posts, such that the posts separate the antenna from the end of the stent body, a generally cylindrical stent body; a plurality of posts protruding longitudinally from an end of the stent body; an antenna disposed annularly on the posts, such that the posts separate the antenna from the end of the stent body, the apparatus further comprises: a transmitter configured to transmit RF energy towards the antenna, such as to generate an inductive current through the antenna; an electrode coupled to the stent; and a control capsule coupled to the stent, the control capsule being configured to be powered using the inductive current of the antenna, and with the control capsule being configured to drive a current into the blood vessel, via the electrode; a transmitter configured to transmit RF energy towards the antenna, such as to generate an inductive current through the antenna; an electrode coupled to the stent; and a control capsule coupled to the stent, the control capsule being configured to be powered using the inductive current of the antenna, and with the control capsule being configured to drive a current into the blood vessel, via the electrode; the posts are configured, by separating the antenna from the end of the stent body, to reduce a strength of the inductive current that is generated in the stent body, due to a magnetic field that is generated by the inductive current of the antenna.
A ventilation device to be attached to a wall opening, especially a wall opening of a heating facility, wherein the ventilation device has: - a member with a member opening and a member frame the front side of which surrounds the member opening and the back side of which faces the wall of the wall opening, wherein the member frame has a circumferential member frame stem extending into the member opening to form an air passage and the member frame stem has at least one cleat with a cleat opening attached to the member frame stem; and - a cover plate having a back side that faces the air passage and on which a positioner is formed to be detachably attached to the cleat of the member frame stem, and a front side that faces away from the air passage and faces the environment, characterized in that a stem is formed on the outer edges of the front side and a plaster holding layer is applied to the surface side of the front side. - a member with a member opening and a member frame the front side of which surrounds the member opening and the back side of which faces the wall of the wall opening, wherein the member frame has a circumferential member frame stem extending into the member opening to form an air passage and the member frame stem has at least one cleat with a cleat opening attached to the member frame stem; and - a cover plate having a back side that faces the air passage and on which a positioner is formed to be detachably attached to the cleat of the member frame stem, and a front side that faces away from the air passage and faces the environment, characterized in that a stem is formed on the outer edges of the front side and a plaster holding layer is applied to the surface side of the front side.
A drive device for an electric vehicle, comprising: an electric motor; a speed reduction unit including an input shaft driven by output of the electric motor; a hub unit rotationally driven by an output member of the speed reduction unit; and a housing accommodating the electric motor and the speed reduction unit, wherein the electric motor is disposed on an outer radial side of the speed reduction unit in the housing and a support member of a rotor of the electric motor is fitted to the input shaft of the speed reduction unit, whereby the input shaft is supported by a pair of bearings (58, 59) disposed at two locations on both sides of an input gear of the speed reduction unit,the pair of bearings (58, 59) at the two locations are together supported by the output member, the pair of bearings (58, 59) being together provided between an inner radial surface of each of a pair of flanges (52, 53) of the output member and an outer radial surface of the input shaft opposing each of the inner radial surfaces of the pair of flanges (52, 53) to support the input shaft, and both of the pair of bearings (58, 59) being disposed on an outboard side of a fitting portion between the input shaft and the rotor support member of the electric motor to form a cantilever support structure, a partition for partitioning an accommodation section into respective accommodation spaces for the electric motor and the speed reduction unit is provided in the housing, a peripheral edge portion of a center hole provided in the partition is disposed close to an outer periphery of a boss portion of the rotor on an inboard side of the pair of bearings (58, 59) at the two locations, and a first oil seal member is placed between the peripheral edge portion of the center hole and the boss portion.
A computer-implemented method for providing single sign-on to remote or cloud-based computing resources, comprising: requesting, via a local network computer, access to a cloud-based resource; passing a request from the local network computer to a local directory services system for a service ticket associated with a cloud-based directory services system through which access may be granted to the cloud-based resource; passing the service ticket associated with the cloud-based directory services system from the local network computer to a cloud-based authentication endpoint associated with the cloud-based directory services system for validating a requesting user associated with the requesting local network computer for access to the requested cloud-based resource; receiving from the cloud-based directory services system validation of the service ticket by the cloud-based directory services system for authenticating the requesting user for access to the requested cloud-based resource; and receiving at the requesting local network computer authorization to access the requested cloud-based resource, and prior to passing the service ticket to the cloud-based authentication endpoint, registering the cloud-based authentication endpoint with the local directory services system as a local device, service or resource for allowing the service ticket to be passed to the cloud-based authentication endpoint as a local endpoint. requesting, via a local network computer, access to a cloud-based resource; passing a request from the local network computer to a local directory services system for a service ticket associated with a cloud-based directory services system through which access may be granted to the cloud-based resource; passing the service ticket associated with the cloud-based directory services system from the local network computer to a cloud-based authentication endpoint associated with the cloud-based directory services system for validating a requesting user associated with the requesting local network computer for access to the requested cloud-based resource; receiving from the cloud-based directory services system validation of the service ticket by the cloud-based directory services system for authenticating the requesting user for access to the requested cloud-based resource; and receiving at the requesting local network computer authorization to access the requested cloud-based resource, and prior to passing the service ticket to the cloud-based authentication endpoint, registering the cloud-based authentication endpoint with the local directory services system as a local device, service or resource for allowing the service ticket to be passed to the cloud-based authentication endpoint as a local endpoint.
An anti-irritant diaper for containing solid waste excreted from a wearer and preventing it from contact with the wearer's skin, the diaper having a front area, a middle area, a rear area, a pair of leg cuffs (36a, 36b) and closing tabs and comprising: a resilient flexible band disposed longitudinally and centrally along the diaper; a pocket formed within said middle area for receiving excreted solid waste and having a space above it, said space separating said pocket from the wearer's skin; and a one-directional flexible partition, situated above said pocket and including a pair of dividers (52a, 52b), each of said dividers attached at one end to one of said pair of leg cuffs (36a, 36b) and segmented into a plurality of flexible flaps; wherein said resilient flexible band maintains the shape of said pocket, and wherein said flaps of said flexible partition are configured to bend downward by the weight of solid waste, so as to allow it to enter into said pocket, and said flaps are further configured to return thereafter to their original position, so as to prevent the waste from contacting the wearer's skin. a resilient flexible band disposed longitudinally and centrally along the diaper; a pocket formed within said middle area for receiving excreted solid waste and having a space above it, said space separating said pocket from the wearer's skin; and a one-directional flexible partition, situated above said pocket and including a pair of dividers (52a, 52b), each of said dividers attached at one end to one of said pair of leg cuffs (36a, 36b) and segmented into a plurality of flexible flaps; wherein said resilient flexible band maintains the shape of said pocket, and wherein said flaps of said flexible partition are configured to bend downward by the weight of solid waste, so as to allow it to enter into said pocket, and said flaps are further configured to return thereafter to their original position, so as to prevent the waste from contacting the wearer's skin.
A system for laparoscopic placement of a cuff around a target biological structure, the system comprising: a guidewire configured to be insertable through an incision in a patient underneath an exterior surface of the target biological structure; a ramp device configured to be guided over the guidewire, the ramp device having a curvature with respect to a long axis of the guidewire and being configured to partly support the target biological structure; and a cuff deployment tool configured to be guided over the guidewire to engage the ramp device, the cuff deployment tool comprising an interior volume and a cuff positioned within the interior volume, wherein the cuff deployment tool is operable to move the cuff from within the interior volume to an extended position, in which at least part of the cuff extends along the curvature of the ramp device onto the target biological structure. a guidewire configured to be insertable through an incision in a patient underneath an exterior surface of the target biological structure; a ramp device configured to be guided over the guidewire, the ramp device having a curvature with respect to a long axis of the guidewire and being configured to partly support the target biological structure; and a cuff deployment tool configured to be guided over the guidewire to engage the ramp device, the cuff deployment tool comprising an interior volume and a cuff positioned within the interior volume, wherein the cuff deployment tool is operable to move the cuff from within the interior volume to an extended position, in which at least part of the cuff extends along the curvature of the ramp device onto the target biological structure.
Sensor system for determining a position of a measured object relative to a sensor, with a sensor for the provision of a measured value, which depends on a distance between a sensor and a measured object, with an evaluation device (22; 30) for evaluation of the measured value and for provision of a measured value result, characterised in that the evaluation device (22; 30) includes a comparing device (31, 36) and a timer, that the comparing device (31, 36) is designed for comparison of a stored measured value with a currently determined measured value, that the comparing device (31, 36) is designed to provide the timer with a control signal when a result of the comparison satisfies a presettable criterion, that the timer is designed so that, on provision of the control signal, a timed measuring process is continued and that, in the absence of the control signal the timed measuring process is restarted, that the timer is so designed that, on reaching a presettable duration of the timed measuring process a trigger signal is output by the timer, and that the evaluation device (22; 30) includes a memory device which is set up for storage of the current measured value on receipt of the trigger signal.
A method of filling a fluid drug formulation within a lumenal space of a hollow wire having a plurality of side openings along a length thereof that forms a stent, the method comprising the steps of: placing a stent formed from a hollow wire having a plurality of side openings within a chamber that houses a fluid drug formulation and a wicking means that is in contact with the fluid drug formulation, wherein the chamber is at or near the vapor-liquid equilibrium of a solvent of the fluid drug formulation; placing a portion of the stent into contact with the wicking means such that at least one of the plurality of side openings is in contact with the wicking means; and maintaining contact between the wicking means and the selected portion of the stent until a lumenal space defined by the hollow wire is filled with the fluid drug formulation via capillary action through the at least one of the plurality of side openings in contact with the wicking means, wherein the term "near the vapor-liquid equilibrium" includes pressure rates within a range of -666.612 Pa/min to 666.612 Pa/min (-5 torr/min to 5 torr/min) placing a stent formed from a hollow wire having a plurality of side openings within a chamber that houses a fluid drug formulation and a wicking means that is in contact with the fluid drug formulation, wherein the chamber is at or near the vapor-liquid equilibrium of a solvent of the fluid drug formulation; placing a portion of the stent into contact with the wicking means such that at least one of the plurality of side openings is in contact with the wicking means; and maintaining contact between the wicking means and the selected portion of the stent until a lumenal space defined by the hollow wire is filled with the fluid drug formulation via capillary action through the at least one of the plurality of side openings in contact with the wicking means, wherein the term "near the vapor-liquid equilibrium" includes pressure rates within a range of -666.612 Pa/min to 666.612 Pa/min (-5 torr/min to 5 torr/min)