A glucose monitoring system, comprising: a glucose sensor configured to be positioned at least in part in contact with interstitial fluid in a body of a user; a transmitter unit configured to process data indicative of a plurality of monitored glucose levels from the glucose sensor; and a receiver unit (104, 200) comprising a processor, and a user interface having a display and an actuator, wherein the receiver unit (104, 200) is configured to receive the processed data from the transmitter unit, wherein the display is configured to render a plurality of display screens, including at least a home screen (300, 390) and an alert screen (1900, 2000, 2100), wherein the home screen (300, 390) is divided into a plurality of simultaneously displayed panels, wherein a first panel (302, 303) of the plurality of panels is configured to display the plurality of monitored glucose levels, wherein a second panel (320, 360) of the plurality of panels is configured to simultaneously display a current glucose level icon and a glucose trend indicator, and wherein a third panel of the plurality of panels is configured to display status information (330, 332, 334, 336) of a plurality of components of the receiver unit (104, 200); wherein the processor is configured to detect an alarm condition in response to the current glucose level being outside predetermined threshold levels; wherein the display is configured to render the alert screen on the display when the alarm condition is detected, the alert screen having information corresponding to the detected alarm condition; wherein the display is further configured to affect a further output of the glucose monitoring system corresponding to the detected alarm condition in response to user actuation of the actuator of the receiver unit (104, 200) to acknowledge the displayed alert screen, wherein the further output comprises returning to the home screen (300, 390) on the display; wherein the processor is configured to cause the display to render the plurality of display screens; and wherein the display is configured to display the current glucose level icon of the second panel (320, 360) of the home screen (300, 390) in a colour coded format based on whether the current glucose level is within or outside the predetermined threshold levels. a glucose sensor configured to be positioned at least in part in contact with interstitial fluid in a body of a user; a transmitter unit configured to process data indicative of a plurality of monitored glucose levels from the glucose sensor; and a receiver unit (104, 200) comprising a processor, and a user interface having a display and an actuator, wherein the receiver unit (104, 200) is configured to receive the processed data from the transmitter unit, wherein the display is configured to render a plurality of display screens, including at least a home screen (300, 390) and an alert screen (1900, 2000, 2100), wherein the home screen (300, 390) is divided into a plurality of simultaneously displayed panels, wherein a first panel (302, 303) of the plurality of panels is configured to display the plurality of monitored glucose levels, wherein a second panel (320, 360) of the plurality of panels is configured to simultaneously display a current glucose level icon and a glucose trend indicator, and wherein a third panel of the plurality of panels is configured to display status information (330, 332, 334, 336) of a plurality of components of the receiver unit (104, 200); wherein the processor is configured to detect an alarm condition in response to the current glucose level being outside predetermined threshold levels; wherein the display is configured to render the alert screen on the display when the alarm condition is detected, the alert screen having information corresponding to the detected alarm condition; wherein the display is further configured to affect a further output of the glucose monitoring system corresponding to the detected alarm condition in response to user actuation of the actuator of the receiver unit (104, 200) to acknowledge the displayed alert screen, wherein the further output comprises returning to the home screen (300, 390) on the display; wherein the processor is configured to cause the display to render the plurality of display screens; and wherein the display is configured to display the current glucose level icon of the second panel (320, 360) of the home screen (300, 390) in a colour coded format based on whether the current glucose level is within or outside the predetermined threshold levels.