A pharmaceutical composition in a dosage form as a lozenge, for the topical treatment of inflammatory diseases of the mouth and throat area, cough and catarrhs of the upper respiratory system, wherein the composition comprises a combination of (a) 0.05 to 30% by weight, based on the pharmaceutical composition, of at least one first active ingredient, containing at least one tanning agent in the form of an extract, having a drug/extract ratio in the range of 1:0.1 to 1:100, wherein the tanning agent is selected from Geranium, blackberry ( Rubus fructiosus), oak (Quercus rubor and/or Quercus petraea), silverweed (Potentilla anserina), clove ( Szygium aromaticum), blueberry (Vaccinium myrtillus), myrrh (Commiphora molmol), Ratanhia ( Krameria triandra), sage (Salvia triloba), blackthorn ( Prunus spinosa), dead-nettle ( Lamium album), common tormentil ( Potentilla erecta), strawberry ( Fragarai vesca), agrimony ( Agrimonia eupatoria), lady's mantle ( Alchemilla xanthochlora), rose ( Rosa gallica), sanguisorba (Sanguisorba officinalis), and the combinations thereof; with (b) 0.01 to 20% by weight, based on the pharmaceutical composition, of at least a second active ingredient, containing at least one mucilage drug in the form of an extract, having a drug/extract ratio in the range of 0.4:1 to 15:1, wherein the mucilage drug is selected from buckhorn plantain (Plantago lanceolata L.), Icelandic moss ( Lichen islandicus), lady's finger ( Althaea officinalis L.), hollyhock (Malva sylvestris L. and M. neglecta WALLR.), fenugreek ( Trigonella foenum-graecum L.), salep and quince ( Cydonia oblonga MILL.), and the combinations thereof; in pharmaceutically effective amounts, wherein the composition has at least a first phase, and at least a second phase being surrounded by the first phase, wherein the first phase has at least the first active ingredient component (a), and the second phase has at least the second active ingredient component (b), wherein the first phase is embodied as a sheath, and the second phase as a core, wherein the first phase is present in a solid form, which is dissolvable during sucking, and/or under the influence of saliva, and wherein the second phase is present in a liquid form, wherein phases and release the active ingredient components (a) and (b) during sucking and/or under the influence of saliva, in a time-delayed manner, wherein the first active ingredient component (a) is chronologically released before the second active ingredient component (b) during sucking and/or under the influence of saliva, wherein the composition contains the active ingredient components (a) and/or (b) independently of each other, each in a matrix, and/or a mass based on sugars and/or sugar substitutes, and wherein the ratio that is based on both the weight of the solid first phase and the liquid second phase is in the range of 50-98:50-2. (a) 0.05 to 30% by weight, based on the pharmaceutical composition, of at least one first active ingredient, containing at least one tanning agent in the form of an extract, having a drug/extract ratio in the range of 1:0.1 to 1:100, wherein the tanning agent is selected from Geranium, blackberry ( Rubus fructiosus), oak (Quercus rubor and/or Quercus petraea), silverweed (Potentilla anserina), clove ( Szygium aromaticum), blueberry (Vaccinium myrtillus), myrrh (Commiphora molmol), Ratanhia ( Krameria triandra), sage (Salvia triloba), blackthorn ( Prunus spinosa), dead-nettle ( Lamium album), common tormentil ( Potentilla erecta), strawberry ( Fragarai vesca), agrimony ( Agrimonia eupatoria), lady's mantle ( Alchemilla xanthochlora), rose ( Rosa gallica), sanguisorba (Sanguisorba officinalis), and the combinations thereof; with (b) 0.01 to 20% by weight, based on the pharmaceutical composition, of at least a second active ingredient, containing at least one mucilage drug in the form of an extract, having a drug/extract ratio in the range of 0.4:1 to 15:1, wherein the mucilage drug is selected from buckhorn plantain (Plantago lanceolata L.), Icelandic moss ( Lichen islandicus), lady's finger ( Althaea officinalis L.), hollyhock (Malva sylvestris L. and M. neglecta WALLR.), fenugreek ( Trigonella foenum-graecum L.), salep and quince ( Cydonia oblonga MILL.), and the combinations thereof;