mhurhangee/ep-ind-claims huggingface dataset:
An integrated circuit, IC, comprising: a substrate having an active layer thereon, the active layer having a first region having a first characteristic impacting or impacted by a local thermal condition and a second region having a second characteristic, different to the first characteristic; a plurality of metal layers positioned above the active layer; and a power distribution network, PDN, comprising: a plurality of pillars (408, 410) extending through at least four metal layers positioned closest to the active layer; and a grid formed from metal traces (414, 416) within the at least four metal layers positioned closest to the active layer, the grid interconnecting at least a subset of the plurality of pillars, wherein the grid extends from the first region into the second region. a substrate having an active layer thereon, the active layer having a first region having a first characteristic impacting or impacted by a local thermal condition and a second region having a second characteristic, different to the first characteristic; a plurality of metal layers positioned above the active layer; and a power distribution network, PDN, comprising: a plurality of pillars (408, 410) extending through at least four metal layers positioned closest to the active layer; and a grid formed from metal traces (414, 416) within the at least four metal layers positioned closest to the active layer, the grid interconnecting at least a subset of the plurality of pillars, wherein the grid extends from the first region into the second region. a plurality of pillars (408, 410) extending through at least four metal layers positioned closest to the active layer; and a grid formed from metal traces (414, 416) within the at least four metal layers positioned closest to the active layer, the grid interconnecting at least a subset of the plurality of pillars, wherein the grid extends from the first region into the second region.
A first computing device configured to: communicate over a network with at least one additional computing device (58b, 62,b); receive interactive content from the at least one additional computing device, wherein said interactive content is a web-page having at least a first interactive field, said first interactive field having an input parameter; receive a schema for said interactive content from said at least one additional computing device (58b, 62b), said schema identifying said input parameter; render said interactive content using said schema; receive input within the first interactive field; and verify that said input conforms with said input parameter based on said schema; characterized in that the first computing device is configured to communicate said input within the first interactive field over the network via a secure connection or via a non-secure connection based upon whether said input conforms with the input parameter of the first interactive field. communicate over a network with at least one additional computing device (58b, 62,b); receive interactive content from the at least one additional computing device, wherein said interactive content is a web-page having at least a first interactive field, said first interactive field having an input parameter; receive a schema for said interactive content from said at least one additional computing device (58b, 62b), said schema identifying said input parameter; render said interactive content using said schema; receive input within the first interactive field; and verify that said input conforms with said input parameter based on said schema; characterized in that the first computing device is configured to communicate said input within the first interactive field over the network via a secure connection or via a non-secure connection based upon whether said input conforms with the input parameter of the first interactive field.
A use of β-(1,3)-glucuronan or β-(1,3)-glucoglucuronan selected from: - the β-(1,3)-D-polyglucuronic acid having molar masses comprised between 500 and 2,500,000 Daltons; - the peracetylated β-(1,3)-D-polyglucuronic acid having molar masses comprised between 600 and 3,500,000 Daltons; and - the β-(1,3)-D-polyglucuronic acid, sulphated in the C2 and C4 positions having molar masses comprised between 800 and 4,000,000 Daltons; as a slimming agent. - the β-(1,3)-D-polyglucuronic acid having molar masses comprised between 500 and 2,500,000 Daltons; - the peracetylated β-(1,3)-D-polyglucuronic acid having molar masses comprised between 600 and 3,500,000 Daltons; and - the β-(1,3)-D-polyglucuronic acid, sulphated in the C2 and C4 positions having molar masses comprised between 800 and 4,000,000 Daltons; as a slimming agent.
A household appliance comprising a body, at least a pair of feet elevating the body from the ground and forming a volume in between, and cleaning means placed underneath the household appliance inside the aforementioned volume, characterized by said cleaning means comprising; - a pair of springs connected to the two opposite ends of the rear of the household appliance from one end, - a pair of holders connected to the other ends of the pair of springs, - a sweeper attached on to the pair of holders so as to extend almost along the width of the household appliance, - a pair of guides provided in close vicinity of the pair of feet towards the front of the household appliance, - a string connected to the pair of holders and extending almost along the depth of the household appliance and towards the pair of guides via which the string is bent and continues to extend almost along the width of the household appliance, - an aperture at the front of the household appliance through which the string reaches out and which upon being pulled, moves the pair of holders and the sweeper along the depth of the household appliance. - a pair of springs connected to the two opposite ends of the rear of the household appliance from one end, - a pair of holders connected to the other ends of the pair of springs, - a sweeper attached on to the pair of holders so as to extend almost along the width of the household appliance, - a pair of guides provided in close vicinity of the pair of feet towards the front of the household appliance, - a string connected to the pair of holders and extending almost along the depth of the household appliance and towards the pair of guides via which the string is bent and continues to extend almost along the width of the household appliance, - an aperture at the front of the household appliance through which the string reaches out and which upon being pulled, moves the pair of holders and the sweeper along the depth of the household appliance.
An organic light emitting diode (OLED) display, comprising: a substrate; a plurality of organic light emitting diodes formed on a surface of the substrate; an encapsulation layer formed on the plurality of organic light emitting diodes; characterised in that a spacer is formed on the substrate and surrounds the encapsulation layer and the plurality of organic light emitting diodes, wherein the spacer directly contacts the encapsulation layer along the perimeter of the encapsulation layer, wherein a height of the spacer is greater than a height of the encapsulation layer, wherein the height is defined from the surface of the substrate. a substrate; a plurality of organic light emitting diodes formed on a surface of the substrate; an encapsulation layer formed on the plurality of organic light emitting diodes; characterised in that a spacer is formed on the substrate and surrounds the encapsulation layer and the plurality of organic light emitting diodes, wherein the spacer directly contacts the encapsulation layer along the perimeter of the encapsulation layer, wherein a height of the spacer is greater than a height of the encapsulation layer, wherein the height is defined from the surface of the substrate.
Method for preventing the crystallization of the pharmaceutical rotigotine in a polymer film, characterized in that the solvent-containing coating material applied for producing the polymer film, comprising a matrix-forming polymer or polymer mixture and rotigotine as pharmaceutical, which is dispersed in the form of a solid solution in the matrix-forming polymer, is dried at temperatures which are 10 to 25 °C above the melting temperature of the pharmaceutical present in the coating material for not longer than 15 minutes.
A modified T cell comprising: a nucleic acid capable of downregulating gene expression of an endogenous TCR α chain, wherein the nucleic acid comprises a CRISPR system comprising a gRNA encoded by SEQ ID NO: 1; a nucleic acid capable of downregulating gene expression of an endogenous TCR β chain, wherein the nucleic acid comprises a CRISPR system; and a nucleic acid encoding a modified T cell receptor comprising affinity for a surface antigen on a target cell. a nucleic acid capable of downregulating gene expression of an endogenous TCR α chain, wherein the nucleic acid comprises a CRISPR system comprising a gRNA encoded by SEQ ID NO: 1; a nucleic acid capable of downregulating gene expression of an endogenous TCR β chain, wherein the nucleic acid comprises a CRISPR system; and a nucleic acid encoding a modified T cell receptor comprising affinity for a surface antigen on a target cell.
A process for preparing a polyisocyanate-based polymer, comprising forming a reaction mixture containing at least one polyisocyanate, at least one isocyanate-reactive compound having at least two isocyanate-reactive groups and at least one zinc catalyst, and then curing the reaction mixture to form a polymer, wherein the zinc catalyst contains at least one zinc atom associated with a polydentate organic ligand that contains at least two complexing sites, of which at least one is nitrogen-containing, wherein the ligand compound is a) a β-amino alcohol or enol; b) a β-imino alcohol or enol; c) a β-enamino alcohol; d) β-amino keto or β-enamino keto or ester compound; e) a β-diketiminate compound; or f) a β-diamine compound. a) a β-amino alcohol or enol; b) a β-imino alcohol or enol; c) a β-enamino alcohol; d) β-amino keto or β-enamino keto or ester compound; e) a β-diketiminate compound; or f) a β-diamine compound.
A pharmaceutical composition for use in preventing or treating an inflammatory disease, the composition comprising a graphene nano-structure as an active ingredient; wherein the graphene nano-structure is nano-sized graphene oxide or a graphene quantum dot; wherein the nano-sized graphene oxide has a thickness of 12 nm or less and an average diameter of 15 to 50 nm; and wherein the inflammatory disease is an inflammatory bowel disease. wherein the graphene nano-structure is nano-sized graphene oxide or a graphene quantum dot; wherein the nano-sized graphene oxide has a thickness of 12 nm or less and an average diameter of 15 to 50 nm; and wherein the inflammatory disease is an inflammatory bowel disease.
A method for processing data, comprising: after receiving data input by a data bus, according to a destination indication of the data and a valid bit field indication of the data, writing the data input by the data bus into an uplink side shared cache; polling the uplink side shared cache according to a fixed timeslot order, reading out data in the uplink side shared cache, and outputting the data to respective corresponding channels; wherein the uplink side shared cache consists of N pieces of random access memory with a specified bit width, and each piece of RAM is logically divided into Y RAM segments; the RAM segments in the same column correspond to the same channel, and are called a RAM segment column; further comprising: in the process of writing the data input by the data bus into the uplink side shared cache, recording a write-in position of tail of current data according to channels; in each write-in, selecting a corresponding RAM segment column according to the destination indication, and taking the RAM segment column of "the last write-in end position + 1" as the start position of the current write-in, and according to the valid bit field indication of the data, determining to pull up the write enable of the "valid bit field" RAM pieces in turn from the start position of the current write-in. after receiving data input by a data bus, according to a destination indication of the data and a valid bit field indication of the data, writing the data input by the data bus into an uplink side shared cache; polling the uplink side shared cache according to a fixed timeslot order, reading out data in the uplink side shared cache, and outputting the data to respective corresponding channels; wherein the uplink side shared cache consists of N pieces of random access memory with a specified bit width, and each piece of RAM is logically divided into Y RAM segments; the RAM segments in the same column correspond to the same channel, and are called a RAM segment column; further comprising: in the process of writing the data input by the data bus into the uplink side shared cache, recording a write-in position of tail of current data according to channels; in each write-in, selecting a corresponding RAM segment column according to the destination indication, and taking the RAM segment column of "the last write-in end position + 1" as the start position of the current write-in, and according to the valid bit field indication of the data, determining to pull up the write enable of the "valid bit field" RAM pieces in turn from the start position of the current write-in. in the process of writing the data input by the data bus into the uplink side shared cache, recording a write-in position of tail of current data according to channels; in each write-in, selecting a corresponding RAM segment column according to the destination indication, and taking the RAM segment column of "the last write-in end position + 1" as the start position of the current write-in, and according to the valid bit field indication of the data, determining to pull up the write enable of the "valid bit field" RAM pieces in turn from the start position of the current write-in.
A cutting tool comprising a cutting insert located in a tool holder, the cutting insert comprising a cutting head and an insert shank extending rearwardly from the cutting head, the cutting insert having a longitudinal insert axis passing through the insert shank and the cutting head; the cutting head comprising a cutting edge formed at an intersection of a rake surface and a relief surface; the insert shank comprising an insert clamping portion extending along the insert axis and having a peripheral surface surrounding the insert axis, the insert axis being located in a first dividing plane of the insert clamping portion, the insert clamping portion having an asymmetric cross section taken perpendicular to the insert axis; wherein: on one side of the first dividing plane, the peripheral surface comprises first and second longitudinally extending depressions (48, 50); on the other side of the first dividing plane, the peripheral surface comprises first and second abutment surfaces (54, 56), the first and second depressions (48, 50) being separated by a third abutment surface; characterised in that the first and second depressions (48, 50) form coolant channels with a clamping surface of the holder and the first and second abutment surfaces (54, 56) are separated by a third depression. on one side of the first dividing plane, the peripheral surface comprises first and second longitudinally extending depressions (48, 50); on the other side of the first dividing plane, the peripheral surface comprises first and second abutment surfaces (54, 56), the first and second depressions (48, 50) being separated by a third abutment surface; characterised in that the first and second depressions (48, 50) form coolant channels with a clamping surface of the holder and the first and second abutment surfaces (54, 56) are separated by a third depression.
A method of preparing a semi-random graft co-polymer comprising the steps of: (a) dissolving a linear polyamine backbone containing W moles of free primary amino groups in an aqueous buffer having a buffering range from pH 7 to pH 8 to obtain solution A having a volume Y; conducting either step B1 or step B2, wherein: Step B1 comprises (b) activating a protective chain containing 0.5-1.2xW carboxyl group by mixing it with 1.7-7.0xW of N-hydroxysuccinimidesulfate (NHSS) and 1.5-3.6xW of 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride in aqueous buffer, pH 4-5.5 to obtain solution B with a final volume of Z, such that W/(Y+Z) = 30-55mM and allowing the activation to proceed for 0-30 min to obtain solution B; (c) adding solution B to solution A to yield solution C; (d) adjusting the pH of solution C to above 6.5; and (e) adding 0.5-1.5xW of additional 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride to solution C after from 2 to 3 hours and waiting until the remaining primary amino groups are 55-40% of the original primary amino (45 to 60% saturation); and Step B2 comprises (b-d) adding a protective chain containing 0.5-1.2xW carboxyl group, 1.7-7.0xW of N-hydroxysuccinimidesulfate (NHSS) and 1.5-3.6xW of 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride to solution A to obtain solution C; and (e) adding 0.5-1.5xW of additional 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride to solution C after from 2 to 3 hours and waiting until the remaining primary amino groups are 55-40% of the original primary amino (45 to 60% saturation). (a) dissolving a linear polyamine backbone containing W moles of free primary amino groups in an aqueous buffer having a buffering range from pH 7 to pH 8 to obtain solution A having a volume Y; conducting either step B1 or step B2, wherein: Step B1 comprises (b) activating a protective chain containing 0.5-1.2xW carboxyl group by mixing it with 1.7-7.0xW of N-hydroxysuccinimidesulfate (NHSS) and 1.5-3.6xW of 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride in aqueous buffer, pH 4-5.5 to obtain solution B with a final volume of Z, such that W/(Y+Z) = 30-55mM and allowing the activation to proceed for 0-30 min to obtain solution B; (c) adding solution B to solution A to yield solution C; (d) adjusting the pH of solution C to above 6.5; and (e) adding 0.5-1.5xW of additional 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride to solution C after from 2 to 3 hours and waiting until the remaining primary amino groups are 55-40% of the original primary amino (45 to 60% saturation); and Step B2 comprises (b-d) adding a protective chain containing 0.5-1.2xW carboxyl group, 1.7-7.0xW of N-hydroxysuccinimidesulfate (NHSS) and 1.5-3.6xW of 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride to solution A to obtain solution C; and (e) adding 0.5-1.5xW of additional 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride to solution C after from 2 to 3 hours and waiting until the remaining primary amino groups are 55-40% of the original primary amino (45 to 60% saturation).
An intraluminal ultrasound imaging device, comprising: a flexible elongate member configured to be positioned within a body lumen of a patient; and an ultrasound imaging assembly coupled to a distal portion of the flexible elongate member and comprising: a flexible substrate comprising a scanner body portion and an attachment portion extending proximally from the scanner body portion, wherein the attachment portion defines a curved path comprising a first curve curving in a first direction and a second curve curving in a different second direction; one or more control circuits mounted on the scanner body portion; one or more transducer elements mounted on the scanner body portion and in communication with the one or more control circuits; and a plurality of conductive traces disposed on the attachment portion, wherein the plurality of conductive traces is in electrical communication with the one or more control circuits, wherein the plurality of conductive traces follows the curved path of the attachment portion, and the device being characterized in that each conductive trace comprises a pattern that bends relative to the curved path of the attachment portion. a flexible elongate member configured to be positioned within a body lumen of a patient; and an ultrasound imaging assembly coupled to a distal portion of the flexible elongate member and comprising: a flexible substrate comprising a scanner body portion and an attachment portion extending proximally from the scanner body portion, wherein the attachment portion defines a curved path comprising a first curve curving in a first direction and a second curve curving in a different second direction; one or more control circuits mounted on the scanner body portion; one or more transducer elements mounted on the scanner body portion and in communication with the one or more control circuits; and a plurality of conductive traces disposed on the attachment portion, wherein the plurality of conductive traces is in electrical communication with the one or more control circuits, wherein the plurality of conductive traces follows the curved path of the attachment portion, and a flexible substrate comprising a scanner body portion and an attachment portion extending proximally from the scanner body portion, wherein the attachment portion defines a curved path comprising a first curve curving in a first direction and a second curve curving in a different second direction; one or more control circuits mounted on the scanner body portion; one or more transducer elements mounted on the scanner body portion and in communication with the one or more control circuits; and a plurality of conductive traces disposed on the attachment portion, wherein the plurality of conductive traces is in electrical communication with the one or more control circuits, wherein the plurality of conductive traces follows the curved path of the attachment portion, and