A method of inducing high-stability and optionally transportable supercooling, the method comprising: providing a device comprising a rigid container containing biological matter in an aqueous media; ensuring the removal of essentially all bulk gas phase from the contained aqueous media; sealing the container with a rigid air-tight closure, wherein the percentage of the volume of bulk gas phase remaining in the aqueous media upon sealing of the container is less than 5%; and cooling the aqueous media to a temperature below 0°C under isochoric thermodynamic conditions, wherein the container further comprises an on-board or off-board pressure sensing implement, a control implement and an energy delivery implement, wherein the pressure sensing implement measures or detects pressure, wherein a change in pressure is used to detect formation or elimination of ice within the aqueous media, wherein the energy delivery implement uses an energy delivery mechanism selected from the group consisting of conductive heating, convective heating, radiative heating, inductive heating, Joule heating, electromagnetic heating, radio heating, and ultrasonic heating, wherein the energy delivery implement delivers energy to melt, dissolve, or otherwise eliminate ice nuclei or crystals, and wherein upon detection of a change in pressure, a routine is triggered within the control implement, wherein the control implement continuously monitors the pressure, and the routine activates the energy delivery implement when the pressure reading surpasses a given first threshold value, and turns off the energy delivery implement when the pressure returns to beneath the first threshold value or a different threshold value. providing a device comprising a rigid container containing biological matter in an aqueous media; ensuring the removal of essentially all bulk gas phase from the contained aqueous media; sealing the container with a rigid air-tight closure, wherein the percentage of the volume of bulk gas phase remaining in the aqueous media upon sealing of the container is less than 5%; and cooling the aqueous media to a temperature below 0°C under isochoric thermodynamic conditions, wherein the container further comprises an on-board or off-board pressure sensing implement, a control implement and an energy delivery implement, wherein the pressure sensing implement measures or detects pressure, wherein a change in pressure is used to detect formation or elimination of ice within the aqueous media, wherein the energy delivery implement uses an energy delivery mechanism selected from the group consisting of conductive heating, convective heating, radiative heating, inductive heating, Joule heating, electromagnetic heating, radio heating, and ultrasonic heating, wherein the energy delivery implement delivers energy to melt, dissolve, or otherwise eliminate ice nuclei or crystals, and wherein upon detection of a change in pressure, a routine is triggered within the control implement, wherein the control implement continuously monitors the pressure, and the routine activates the energy delivery implement when the pressure reading surpasses a given first threshold value, and turns off the energy delivery implement when the pressure returns to beneath the first threshold value or a different threshold value.