mhurhangee/ep-ind-claims huggingface dataset:
A method for selectively inserting or replacing media content in scheduled media content for each of a plurality of client devices comprising the steps of: sending, via an ad decisions unit to a respective client device in response to a first request for substitute media content, a first response including a time during an ad decision window to send a subsequent request; selecting the substitute media content to be inserted in scheduled media content for the respective client device; sending, to the respective client device in response to the subsequent request, a subsequent response including data associated with the substitute media content; downloading the substitute media content to the respective client device, wherein the substitute media content is downloaded on receiving the subsequent response; signalling to the plurality of client devices a playback time for the downloaded substitute media content, after the step of downloading the substitute media content; and playing the downloaded substitute media content on the client devices at the playback time in place of scheduled media content at the playback time; wherein the step of selecting media content is performed by one or more content selection servers connected to a plurality of client devices; and wherein the ad decisions unit manages the timing of all subsequent requests made by the plurality of client devices for the ad decision window such that all subsequent requests for the ad decision window are spread within the ad decision window. sending, via an ad decisions unit to a respective client device in response to a first request for substitute media content, a first response including a time during an ad decision window to send a subsequent request; selecting the substitute media content to be inserted in scheduled media content for the respective client device; sending, to the respective client device in response to the subsequent request, a subsequent response including data associated with the substitute media content; downloading the substitute media content to the respective client device, wherein the substitute media content is downloaded on receiving the subsequent response; signalling to the plurality of client devices a playback time for the downloaded substitute media content, after the step of downloading the substitute media content; and playing the downloaded substitute media content on the client devices at the playback time in place of scheduled media content at the playback time; wherein the step of selecting media content is performed by one or more content selection servers connected to a plurality of client devices; and wherein the ad decisions unit manages the timing of all subsequent requests made by the plurality of client devices for the ad decision window such that all subsequent requests for the ad decision window are spread within the ad decision window.
A blender system (100, 200, 300) comprising: a base; a container selectively attached with the base; a blending mechanism positioned in the container; a memory (102, 202, 302) storing at least one recipe; a processor (104, 204, 304), communicatively coupled to the memory (102, 202), wherein the processor (104, 204, 304) generates a blending process comprising a series of blender motor speeds to operate the blender blade at the given speed and a series of time intervals corresponding to the given motor speeds, wherein the processor (104, 204, 304) generates the blending process at least as a function of a set of ingredients of the at least one recipe and executes at least one instruction of the blending process to operate at least one of the blending mechanism and the container; and a wireless communication device communicatively coupled to the processor to modify the at least one recipe, characterized in that the wireless communication device further receives a rating identifying a user's affinity for a blended product and communicates the rating to a network, wherein the processor (104, 204, 304) receives data related to the rating identifying the user's affinity for the blended product, and wherein the processor (104, 204, 304) applies the data to modify the at least one recipe. a base; a container selectively attached with the base; a blending mechanism positioned in the container; a memory (102, 202, 302) storing at least one recipe; a processor (104, 204, 304), communicatively coupled to the memory (102, 202), wherein the processor (104, 204, 304) generates a blending process comprising a series of blender motor speeds to operate the blender blade at the given speed and a series of time intervals corresponding to the given motor speeds, wherein the processor (104, 204, 304) generates the blending process at least as a function of a set of ingredients of the at least one recipe and executes at least one instruction of the blending process to operate at least one of the blending mechanism and the container; and a wireless communication device communicatively coupled to the processor to modify the at least one recipe, characterized in that the wireless communication device further receives a rating identifying a user's affinity for a blended product and communicates the rating to a network, wherein the processor (104, 204, 304) receives data related to the rating identifying the user's affinity for the blended product, and wherein the processor (104, 204, 304) applies the data to modify the at least one recipe.
A method of determining the methylation status of a target nucleic acid molecule in a sample, wherein the method comprises the steps of: (a) bisulfite treatment of the sample for converting the unmethylated cytosine bases in the target nucleic acid molecule to uracil; (b) amplifying at least part of the converted target nucleic acid molecule, said part comprising a target region the methylation status of which is to be analyzed, in a polymerase chain reaction, using a pair of methylation-specific primers under conditions allowing such amplification to generate PCR amplification products (amplicons); (c) contacting the amplicons with a methylation-specific plasmonic nanoprobe comprising a plasmonic nanoparticle and a non-ionic oligonucleotide analog probe covalently coupled thereto, the oligonucleotide analog probe comprising a base sequence that is complementary to the target region, under conditions that allow the oligonucleotide analog probe and the amplicons comprising the target region to hybridize to each other, wherein the probe generates a detectable signal if hybridized to the target nucleic acid molecule that is distinguishable from the signal of the unhybridized probe; (d) determining the methylation status of the target nucleic acid molecule based on the determination of the melting temperature T m of the hybrid of the nanoprobe and the target nucleic acid. (a) bisulfite treatment of the sample for converting the unmethylated cytosine bases in the target nucleic acid molecule to uracil; (b) amplifying at least part of the converted target nucleic acid molecule, said part comprising a target region the methylation status of which is to be analyzed, in a polymerase chain reaction, using a pair of methylation-specific primers under conditions allowing such amplification to generate PCR amplification products (amplicons); (c) contacting the amplicons with a methylation-specific plasmonic nanoprobe comprising a plasmonic nanoparticle and a non-ionic oligonucleotide analog probe covalently coupled thereto, the oligonucleotide analog probe comprising a base sequence that is complementary to the target region, under conditions that allow the oligonucleotide analog probe and the amplicons comprising the target region to hybridize to each other, wherein the probe generates a detectable signal if hybridized to the target nucleic acid molecule that is distinguishable from the signal of the unhybridized probe; (d) determining the methylation status of the target nucleic acid molecule based on the determination of the melting temperature T m of the hybrid of the nanoprobe and the target nucleic acid.
A hybrid polypeptide having cellulolytic activity, comprising: (a) a fragment at the N-terminal end of the hybrid polypeptide comprising the heterologous catalytic domain of a cellulolytic enzyme; and (b) a fragment at the C-terminal end of the first polypeptide fragment comprising a carbohydrate binding module variant, wherein the CBM variant comprises a substitution at a position corresponding to position 31 of SEQ ID NO: 4, and wherein the CBM variant has at least 90%, at least 91%, at least 92%, at least 93%, at least 94%, at least 95%, at least 96%, at least 97%, at least 98%, or at least 99%, but less than 100%, sequence identity to SEQ ID NO: 20, and wherein the CBM variant comprises a Y31W substitution at the position corresponding to position 31 of SEQ ID NO: 4, and wherein the N-terminal end of the hybrid polypeptide comprises the heterologous catalytic domain having a sequence identity to amino acids 1 to 437 of SEQ ID NO: 46 of at least 90%, at least 91%, at least 92%, at least 93%, at least 94%, at least 95%, at least 96%, at least 97%, at least 98%, at least 99%, or 100%, which have cellobiohydrolase activity. (a) a fragment at the N-terminal end of the hybrid polypeptide comprising the heterologous catalytic domain of a cellulolytic enzyme; and (b) a fragment at the C-terminal end of the first polypeptide fragment comprising a carbohydrate binding module variant,
A ropeless elevator system comprising a motor and drive system, said motor and drive system comprising: at least one direct current source (Vdc/2 +, Vdc/2 -); a six phase inverter (305, 405) switching between positive and negative power of the at least one direct current source; and a six phase machine (310, 410) including six phase windings (a1, b1, c1, a2, b2, c2) divided into at least two windings groups (a1, b1, c1; a2, b2, c2); and a six-phase power converter configured to drive the motor and drive system; characterized in that: the six-phase power converter includes one phase-leg of two switches connected to one phase of the six phase windings; wherein the motor and drive system is arranged to produce an active control signal, said active control signal being configured to result in a zero common-mode pulse width modulation across the at least two windings groups (a1, b1, c1; a2, b2, c2); wherein a switching pattern of the six-phase power converter is arranged for the at least two windings groups (a1, b1, c1; a2, b2, c2); and wherein the switching actions of the switching pattern are complementary for the at least two windings groups (a1, b1, c1; a2, b2, c2) to maintain a common-mode voltage at zero. at least one direct current source (Vdc/2 +, Vdc/2 -); a six phase inverter (305, 405) switching between positive and negative power of the at least one direct current source; and a six phase machine (310, 410) including six phase windings (a1, b1, c1, a2, b2, c2) divided into at least two windings groups (a1, b1, c1; a2, b2, c2); and a six-phase power converter configured to drive the motor and drive system; characterized in that: the six-phase power converter includes one phase-leg of two switches connected to one phase of the six phase windings; wherein the motor and drive system is arranged to produce an active control signal, said active control signal being configured to result in a zero common-mode pulse width modulation across the at least two windings groups (a1, b1, c1; a2, b2, c2); wherein a switching pattern of the six-phase power converter is arranged for the at least two windings groups (a1, b1, c1; a2, b2, c2); and wherein the switching actions of the switching pattern are complementary for the at least two windings groups (a1, b1, c1; a2, b2, c2) to maintain a common-mode voltage at zero. the six-phase power converter includes one phase-leg of two switches connected to one phase of the six phase windings; wherein the motor and drive system is arranged to produce an active control signal, said active control signal being configured to result in a zero common-mode pulse width modulation across the at least two windings groups (a1, b1, c1; a2, b2, c2); wherein a switching pattern of the six-phase power converter is arranged for the at least two windings groups (a1, b1, c1; a2, b2, c2); and wherein the switching actions of the switching pattern are complementary for the at least two windings groups (a1, b1, c1; a2, b2, c2) to maintain a common-mode voltage at zero.
An electromagnetic sampling device, comprising: a needle comprising a hollow housing extending from a proximal end to a distal end, and an electromagnet comprising an electromagnetic coil and a metal core, wherein activation of said electromagnetic coil magnetizes the metal core and causes the metal core to attract magnetic particles; wherein at least a portion of said metal core is extendible through said hollow housing of the needle; characterized in that the metal core is configured to transition between: an extended position in which the distal end of the metal core extends beyond the distal end of the needle's hollow housing, and a retracted position in which the distal end of the metal core and any magnetic particles attached thereto are positioned within the needle's housing. a needle comprising a hollow housing extending from a proximal end to a distal end, and an electromagnet comprising an electromagnetic coil and a metal core, wherein activation of said electromagnetic coil magnetizes the metal core and causes the metal core to attract magnetic particles; wherein at least a portion of said metal core is extendible through said hollow housing of the needle; characterized in that the metal core is configured to transition between: an extended position in which the distal end of the metal core extends beyond the distal end of the needle's hollow housing, and a retracted position in which the distal end of the metal core and any magnetic particles attached thereto are positioned within the needle's housing. an extended position in which the distal end of the metal core extends beyond the distal end of the needle's hollow housing, and a retracted position in which the distal end of the metal core and any magnetic particles attached thereto are positioned within the needle's housing.
Composition for topical application comprising, in a physiologically acceptable medium, at least one naphthoic acid derivative, benzoyl peroxide and at least one film-forming agent, characterized in that said naphthoic acid derivative is a compound of formula: in which R represents a hydrogen atom, a hydroxyl radical, a branched or unbranched alkyl radical containing from 1 to 4 carbon atoms, an alkoxy radical containing from 1 to 10 carbon atoms or a cycloaliphatic radical, and in that the film-forming agent is sodium hyaluronate.
A method for preparing an aqueous suspension of nanocapsules comprising an oily core surrounded by a polymeric shell, in which method the following phases are mixed: a) a first phase, called an oily phase, comprising: • a hydrophobic polymer, • an oil or a mixture of oils, • at least one active ingredient, • and a surfactant TA 1, this oily phase being brought to a temperature T 1 higher than the melting point of the hydrophobic polymer, the hydrophobic polymer being miscible, at this temperature T 1, with the mixture of the surfactant TA 1 and the oil or mixture of oils, and the active ingredient being miscible, soluble or solubilized in the mixture of the surfactant TA 1 and the oil or mixture of oils; b) a second phase, called a polar phase, comprising a hydrophilic polymer in the form of a hydrogel in an aqueous solution containing a surfactant TA 2, in such a way as to obtain the formation of the nanocapsules in an aqueous suspension. a) a first phase, called an oily phase, comprising: • a hydrophobic polymer, • an oil or a mixture of oils, • at least one active ingredient, • and a surfactant TA 1, this oily phase being brought to a temperature T 1 higher than the melting point of the hydrophobic polymer, the hydrophobic polymer being miscible, at this temperature T 1, with the mixture of the surfactant TA 1 and the oil or mixture of oils, and the active ingredient being miscible, soluble or solubilized in the mixture of the surfactant TA 1 and the oil or mixture of oils; • a hydrophobic polymer, • an oil or a mixture of oils, • at least one active ingredient, • and a surfactant TA 1, b) a second phase, called a polar phase, comprising a hydrophilic polymer in the form of a hydrogel in an aqueous solution containing a surfactant TA 2,
A composition capable of detecting and typing viruses that cause a respiratory tract infection, the composition simultaneously comprising: a novel coronavirus 2019-nCoV forward primer as shown in SEQ ID NO: 1, a novel coronavirus 2019-nCoV reverse primer as shown in SEQ ID NO: 2, and a novel coronavirus 2019-nCoV probe as shown in SEQ ID NO: 3; and at least one of the following two groups: a first group: an influenza A virus forward primer as shown in SEQ ID NO: 7, an influenza A virus reverse primer as shown in SEQ ID NO: 8, and an influenza A virus probe as shown in SEQ ID NO: 9; and a second group: an influenza B virus forward primer as shown in SEQ ID NO: 10, an influenza B virus reverse primer as shown in SEQ ID NO: 11, and an influenza B virus probe as shown in SEQ ID NO: 12, where fluorescent groups of the probes are different from each other and do not interfere with each other. a first group: an influenza A virus forward primer as shown in SEQ ID NO: 7, an influenza A virus reverse primer as shown in SEQ ID NO: 8, and an influenza A virus probe as shown in SEQ ID NO: 9; and a second group: an influenza B virus forward primer as shown in SEQ ID NO: 10, an influenza B virus reverse primer as shown in SEQ ID NO: 11, and an influenza B virus probe as shown in SEQ ID NO: 12, where fluorescent groups of the probes are different from each other and do not interfere with each other.
A submersible agitator device for circulating drinking water, comprising a submersible motor comprising a cylindrical housing, from one end of which there extends a shaft, a hyperboloid agitator mounted on the shaft, a frame with a plurality of supports extending along the housing and connected to the housing, wherein the supports have radially outwardly angled bend portions, which extend over a peripheral edge of the hyperboloid agitator body in order to support the frame on a base, a flow-guiding element, which is annular in plan view and which is mounted on the bend portions of the supports, wherein transport ribs are provided on an upper side of the hyperboloid agitator body facing the submersible motor and extend in the radial direction and bend towards the peripheral edge in a first tangential direction and wherein, in a plan view of the upper side of the hyperboloid agitator element, the bend portions of the supports bend in a second tangential direction opposite the first tangential direction. a submersible motor comprising a cylindrical housing, from one end of which there extends a shaft, a hyperboloid agitator mounted on the shaft, a frame with a plurality of supports extending along the housing and connected to the housing, wherein the supports have radially outwardly angled bend portions, which extend over a peripheral edge of the hyperboloid agitator body in order to support the frame on a base, a flow-guiding element, which is annular in plan view and which is mounted on the bend portions of the supports, wherein transport ribs are provided on an upper side of the hyperboloid agitator body facing the submersible motor and extend in the radial direction and bend towards the peripheral edge in a first tangential direction and wherein, in a plan view of the upper side of the hyperboloid agitator element, the bend portions of the supports bend in a second tangential direction opposite the first tangential direction.
A method of detecting a membrane protein by mass spectrometry, wherein the method comprises: (a) providing a solution comprising a native membrane vesicle having a lipid bilayer to which said membrane protein is attached; (b) sonicating the vesicle in the presence of a mass spectrometry-compatible buffer; (c) providing a mass spectrometer comprising a nanoelectrospray ionisation source, a mass analyser and a detector; (d) vaporising the sonicated solution using the nanoelectrospray ionisation source under conditions such that the membrane protein is released from the vesicle; (e) ionising the membrane protein; (f) resolving the ionised membrane protein using the mass analyser; and (g) detecting the resolved membrane protein using the detector. (a) providing a solution comprising a native membrane vesicle having a lipid bilayer to which said membrane protein is attached; (b) sonicating the vesicle in the presence of a mass spectrometry-compatible buffer; (c) providing a mass spectrometer comprising a nanoelectrospray ionisation source, a mass analyser and a detector; (d) vaporising the sonicated solution using the nanoelectrospray ionisation source under conditions such that the membrane protein is released from the vesicle; (e) ionising the membrane protein; (f) resolving the ionised membrane protein using the mass analyser; and (g) detecting the resolved membrane protein using the detector.
An exhaust turbocharger turbine wheel comprising: a hub that comprises a nose, a backdisk with a shaft joint portion, and a rotational axis; a plurality of blades that extend from the hub to define a plurality of exhaust flow channels wherein each of the blades comprises a leading edge, a trailing edge, a hub profile, a shroud profile, a pressure side, and a suction side; wherein the backdisk comprises an outer perimeter radius measured from the rotational axis of the hub, an intermediate radius at an outer perimeter of the shaft joint portion measured from the rotational axis of the hub, the outer perimeter radius being different to the intermediate radius, the turbine wheel characterized by an annular recess disposed between the intermediate radius and the outer perimeter radius and defined in part by a plurality of three-dimensional bolster regions, wherein each of the three-dimensional bolster regions comprises an outward bulge in the backdisk, wherein the bulge is into the annular recess, and wherein each of the three-dimensional bolster regions comprises a footprint and a height measured at least in part in a direction of the rotational axis of the hub. a hub that comprises a nose, a backdisk with a shaft joint portion, and a rotational axis; a plurality of blades that extend from the hub to define a plurality of exhaust flow channels wherein each of the blades comprises a leading edge, a trailing edge, a hub profile, a shroud profile, a pressure side, and a suction side; wherein the backdisk comprises an outer perimeter radius measured from the rotational axis of the hub, an intermediate radius at an outer perimeter of the shaft joint portion measured from the rotational axis of the hub, the outer perimeter radius being different to the intermediate radius, the turbine wheel characterized by an annular recess disposed between the intermediate radius and the outer perimeter radius and defined in part by a plurality of three-dimensional bolster regions, wherein each of the three-dimensional bolster regions comprises an outward bulge in the backdisk, wherein the bulge is into the annular recess, and wherein each of the three-dimensional bolster regions comprises a footprint and a height measured at least in part in a direction of the rotational axis of the hub.
A patient support apparatus for use in a room having a room surface, the patient support apparatus comprising a frame including a base frame and an upper frame supported above the base frame and configured to support a patient, the upper frame having a head end, a foot end, and a pair of laterally spaced apart sides, the head end and foot end being spaced apart in a longitudinal dimension of the patient support apparatus, an alert light module coupled to the frame and having a plurality of light emitters, each light emitter being operable to project onto the room surface a lighted iconic image having a shape associated with a monitored condition of the patient support apparatus.