mhurhangee/ep-ind-claims huggingface dataset:
An ophthalmic composition comprising, in an aqueous medium: sulfasalazine or its salt and hyaluronic acid or its salt as an active ingredient; and polyoxyl 40 stearate as a solubilizing agent, wherein the polyoxyl 40 stearate is contained in an amount of 0.01 to 2 wt% based on the total weight of the composition, wherein the aqueous medium is phosphate buffer or citrate buffer, if the citrate buffer is used, a pH is less than 6, and if the phosphate buffer is used, the composition does not contain PVP and does not contain Tocopheryl (vitamin E) polyethylene glycolsuccinate. wherein the polyoxyl 40 stearate is contained in an amount of 0.01 to 2 wt% based on the total weight of the composition, wherein the aqueous medium is phosphate buffer or citrate buffer, if the citrate buffer is used, a pH is less than 6, and if the phosphate buffer is used, the composition does not contain PVP and does not contain Tocopheryl (vitamin E) polyethylene glycolsuccinate.
A caster comprising: a body; a wheel (24, 26) operatively rotatably connected to the body and being rotatable about a wheel axis; a wheel lock movable between a locked position in which the wheel (24, 26) is prevented from rotation about the wheel axis and an unlocked position in which the wheel (24, 26) is rotatable about the wheel axis; a stem operatively connected to the body and being rotatable about a stem axis, the stem axis being perpendicular to the wheel axis; and a stem lock movable between a fixed position in which the stem is prevented from rotation about the stem axis and a swivel position in which the stem is rotatable about the stem axis, and wherein when the wheel lock is in the unlocked position, the wheel lock engages the stem lock to maintain the stem lock in the swivel position, characterised in that the stem lock comprises an interlocking spline shaft and spline bushing, the spline shaft having a longitudinal axis parallel to the stem axis, the spline bushing having a center axis aligned with the spline shaft; wherein when the stem lock is in the swivel position, the spline shaft is spaced from the spline bushing along the spline shaft axis, and when the stem lock is in the fixed position, the spline shaft engages the spline bushing along the spline shaft axis, and further characterised in that when the wheel lock is in the locked position, the wheel lock disengages from the stem lock allowing the stem lock to move to the fixed position. a body; a wheel (24, 26) operatively rotatably connected to the body and being rotatable about a wheel axis; a wheel lock movable between a locked position in which the wheel (24, 26) is prevented from rotation about the wheel axis and an unlocked position in which the wheel (24, 26) is rotatable about the wheel axis; a stem operatively connected to the body and being rotatable about a stem axis, the stem axis being perpendicular to the wheel axis; and a stem lock movable between a fixed position in which the stem is prevented from rotation about the stem axis and a swivel position in which the stem is rotatable about the stem axis, and wherein when the wheel lock is in the unlocked position, the wheel lock engages the stem lock to maintain the stem lock in the swivel position, characterised in that the stem lock comprises an interlocking spline shaft and spline bushing, the spline shaft having a longitudinal axis parallel to the stem axis, the spline bushing having a center axis aligned with the spline shaft; wherein when the stem lock is in the swivel position, the spline shaft is spaced from the spline bushing along the spline shaft axis, and when the stem lock is in the fixed position, the spline shaft engages the spline bushing along the spline shaft axis, and further characterised in that when the wheel lock is in the locked position, the wheel lock disengages from the stem lock allowing the stem lock to move to the fixed position.
An antenna, particularly for installation on a vehicle, such as an aircraft or a high velocity train or a motor vehicle, comprising a main circular reflector, an illuminator or feed, centrally mounted with respect to said main reflector, and a sub-reflector, mounted on said illuminator by means of support member, said sub-reflector has a disc with a centrally placed cusp, so as to reduce the reflection of the sub-reflector upon said illuminator, characterized in that said main reflector is provided with a central hole, in that said illuminator comprises a lower flange, having the same dimensions of said hole of said main reflector, and a spacer ring nut, and in that said support member comprises a lower ring nut adapted to space it from said sub-reflector, said lower ring nut being coupled with said illuminator
A control system for a gas turbine, comprising: a controller comprising a processor, wherein the processor is configured to: receive a plurality of signals from sensors disposed in a turbine system, wherein the turbine system comprises a compressor system; derive a compressor efficiency and a turbine heat rate based on the plurality of signals; determine if an online water wash, an offline water wash, or a combination thereof, should be executed; and if it is determined that the online water wash, the offline water wash, or the combination thereof, should be executed, then executing the online water wash, the offline water wash, or the combination thereof, wherein the online water wash comprises a low pressure compressor, LPC, online water wash, wherein the compressor efficiency comprises a low pressure compressor, LPC, adiabatic efficiency, wherein determining if the online water wash should be executed comprises determining if a LPC efficiency difference, LPCDIF, is within a first range and determining if a heat range percentage, HRPCT, is within a second range, and executing the online water wash comprises executing a LPC online water wash. receive a plurality of signals from sensors disposed in a turbine system, wherein the turbine system comprises a compressor system; derive a compressor efficiency and a turbine heat rate based on the plurality of signals; determine if an online water wash, an offline water wash, or a combination thereof, should be executed; and if it is determined that the online water wash, the offline water wash, or the combination thereof, should be executed, then executing the online water wash, the offline water wash, or the combination thereof, wherein the online water wash comprises a low pressure compressor, LPC, online water wash, wherein the compressor efficiency comprises a low pressure compressor, LPC, adiabatic efficiency, wherein determining if the online water wash should be executed comprises determining if a LPC efficiency difference, LPCDIF, is within a first range and determining if a heat range percentage, HRPCT, is within a second range, and executing the online water wash comprises executing a LPC online water wash.
Device for applying a product to be distributed on the skin of a user by iontophoresis comprising: - at least one means of storage for storing the product to be distributed; - at least one distribution cavity able to receive the product to be distributed; - at least one first electrode for iontophoresis; - an electronic control circuit; - means for measuring a physical or physicochemical parameter connected to the electronic control circuit and configured to send a signal (E 1, E 11, E 12) indicating the parameter measurement, characterised in that the first electrode for iontophoresis and the means for measuring are installed in the distribution cavity, the electronic control circuit being configured to compare the measured value of the physical or physicochemical parameter in the cavity with a threshold reference value (E 2, E 21, E 22) so as to detect an absence of product in the cavity. - at least one means of storage for storing the product to be distributed; - at least one distribution cavity able to receive the product to be distributed; - at least one first electrode for iontophoresis; - an electronic control circuit; - means for measuring a physical or physicochemical parameter connected to the electronic control circuit and configured to send a signal (E 1, E 11, E 12) indicating the parameter measurement,
A polypeptide capable of specifically binding to both CTLA-4 and CD40, said polypeptide comprising B1 and B2, wherein: B1 is an antibody, or antigen binding fragment thereof, specific for CD40, and which is a CD40 agonist; and B2 is a polypeptide binding domain specific for CTLA-4, which comprises or consists of: i) the amino acid sequence of SEQ ID NO: 3; or ii) an amino acid sequence in which at least one amino acid is changed when compared to the amino acid sequence of SEQ ID NO: 3 provided that said binding domain binds to human CTLA-4 with higher affinity than wild-type human CD86. B1 is an antibody, or antigen binding fragment thereof, specific for CD40, and which is a CD40 agonist; and B2 is a polypeptide binding domain specific for CTLA-4, which comprises or consists of: i) the amino acid sequence of SEQ ID NO: 3; or ii) an amino acid sequence in which at least one amino acid is changed when compared to the amino acid sequence of SEQ ID NO: 3 provided that said binding domain binds to human CTLA-4 with higher affinity than wild-type human CD86. i) the amino acid sequence of SEQ ID NO: 3; or ii) an amino acid sequence in which at least one amino acid is changed when compared to the amino acid sequence of SEQ ID NO: 3 provided that said binding domain binds to human CTLA-4 with higher affinity than wild-type human CD86.
A composition for use in an automated cellular analyzer that uses liquid volumetric metering, the composition comprising: a) a chelating agent present at a concentration of 0.05 g/L to 6.0 g/L, b) an ionizing salt present at a concentration of 0.1 g/L to 5 g/L, and c) a non-hemolytic surfactant present at a concentration of 0.1 g/L to 3.0 g/L, wherein the composition is non-hemolytic, has a pH of 6.5 to 7.5, and wherein: i) the surface tension of the composition is between 0.04 N/m (40 dynes/cm) and 0.066 N/m (66 dynes/cm); or ii) the composition produces a meniscus with an angle between 30° and 60° when flowing through a metering tube; or iii) the composition produces a meniscus with an angle between 30° and 60° in a borosilicate glass capillary with an internal diameter of 2.7 mm. a) a chelating agent present at a concentration of 0.05 g/L to 6.0 g/L, b) an ionizing salt present at a concentration of 0.1 g/L to 5 g/L, and c) a non-hemolytic surfactant present at a concentration of 0.1 g/L to 3.0 g/L, i) the surface tension of the composition is between 0.04 N/m (40 dynes/cm) and 0.066 N/m (66 dynes/cm); or ii) the composition produces a meniscus with an angle between 30° and 60° when flowing through a metering tube; or iii) the composition produces a meniscus with an angle between 30° and 60° in a borosilicate glass capillary with an internal diameter of 2.7 mm.
A method for determining and adjusting a flow rate of a blood delivery pump of a blood treatment apparatus, the method comprising: - connecting a container, which is filled with fluid, with an arterial line or arterial port of an extracorporeal blood line of the blood treatment apparatus; - performing a priming step to prime the extracorporeal blood line by driving the blood delivery pump at a predetermined theoretical delivery rate to deliver fluid from the container into the extracorporeal blood line; the method being characterized by: - determining the loss of fluid of the fluid filled container due to delivery of fluid into the extracorporeal blood line during priming; - determining a correction factor during priming by comparison of a value for an amount of fluid delivered under the theoretical delivery rate with a value for an amount of fluid delivered in real; and - pre-tensioning the determined correction factor to a higher delivery rate such that the blood flow is kept within the acceptable tolerance range in the usual inlet arterial pressure range. - connecting a container, which is filled with fluid, with an arterial line or arterial port of an extracorporeal blood line of the blood treatment apparatus; - performing a priming step to prime the extracorporeal blood line by driving the blood delivery pump at a predetermined theoretical delivery rate to deliver fluid from the container into the extracorporeal blood line; - determining the loss of fluid of the fluid filled container due to delivery of fluid into the extracorporeal blood line during priming; - determining a correction factor during priming by comparison of a value for an amount of fluid delivered under the theoretical delivery rate with a value for an amount of fluid delivered in real; and - pre-tensioning the determined correction factor to a higher delivery rate such that the blood flow is kept within the acceptable tolerance range in the usual inlet arterial pressure range.
A method for producing a circumferential packaging for a paper roll, the paper roll having a wound paper web and two opposing end faces and a circumferential surface that connects the end faces to each other, the method comprising the following steps: - applying a protective material in liquid form to an end section of the paper web by means of at least one application unit, the protective material being applied to one or two sides of the end section of the paper web. - winding up the end section of the paper web, so that the end section forms at least one outer layer of the paper roll, and - curing the protective material thereby creating a protective layer that covers the circumferential layer. - applying a protective material in liquid form to an end section of the paper web by means of at least one application unit, the protective material being applied to one or two sides of the end section of the paper web. - winding up the end section of the paper web, so that the end section forms at least one outer layer of the paper roll, and - curing the protective material thereby creating a protective layer that covers the circumferential layer.
Use of Kluyveromyces marxianus yeast for reducing FODMAP (Fermentable oligo-, di-, monosaccharides and polyols) content of wholemeal bread or wholemeal dough by 80 % compared to being prepared by a S. cerevisiae reference strain.
A semiconductor die comprising: • a substrate, the substrate having boundaries defined by a substrate termination edge, wherein the substrate comprises an active area in which one or more active devices are provided; • a first passivation layer over the active area and the substrate, the first passivation layer terminating at a first passivation termination edge that is inset from the substrate termination edge by a first distance; • a second passivation layer over the first passivation layer and the substrate, the second passivation layer terminating at a second passivation termination edge that is inset from the substrate termination edge by a second distance, wherein the second distance is less than the first distance such that the second passivation layer overlaps the first passivation layer, wherein the second passivation layer is directly on the first passivation termination edge directly at a surface of the substrate; characterized by • a barrier region surrounding the active area and configured to electrically isolate the active area from the substrate termination edge, wherein the barrier region terminates at a barrier region outer edge that is inset from the substrate termination edge by a third distance (D3, D4), wherein the third distance (D3, D4) is greater than the second distance and less than the first distance; and • a charge redistribution path formed by a region between the barrier region outer edge and the substrate termination edge. • a substrate, the substrate having boundaries defined by a substrate termination edge, wherein the substrate comprises an active area in which one or more active devices are provided; • a first passivation layer over the active area and the substrate, the first passivation layer terminating at a first passivation termination edge that is inset from the substrate termination edge by a first distance; • a second passivation layer over the first passivation layer and the substrate, the second passivation layer terminating at a second passivation termination edge that is inset from the substrate termination edge by a second distance, wherein the second distance is less than the first distance such that the second passivation layer overlaps the first passivation layer, wherein the second passivation layer is directly on the first passivation termination edge directly at a surface of the substrate; characterized by • a barrier region surrounding the active area and configured to electrically isolate the active area from the substrate termination edge, wherein the barrier region terminates at a barrier region outer edge that is inset from the substrate termination edge by a third distance (D3, D4), wherein the third distance (D3, D4) is greater than the second distance and less than the first distance; and • a charge redistribution path formed by a region between the barrier region outer edge and the substrate termination edge.
Feedthrough in a housing component, in particular for harsh environments subject to mechanical and thermal loading, comprising an inner conductor, an outer conductor and an electrically insulating component between the outer conductor and the inner conductor, the electrically insulating component preferably comprising a glass, in particular a crystallizable or at least partially crystallized glass, or a glass ceramic and retaining the inner conductor relative to the outer conductor in electrically insulated fashion, wherein a sleeve is assigned to or is formed on the outer conductor and retains or makes it possible to fasten this feedthrough on a housing component that is subject to thermal loading, in particular a functional assembly of the exhaust gas system of a motor vehicle, characterized in that a gap (S P) is formed through the sleeve between the outer lateral surface of the outer conductor and an inner surface of the sleeve in such a way that, in the event of vibrations, or forces that are exerted on the inner conductor and trigger a tilting movement, no damage is done to the outer conductor and the sleeve. an inner conductor, an outer conductor and an electrically insulating component between the outer conductor and the inner conductor, the electrically insulating component preferably comprising a glass, in particular a crystallizable or at least partially crystallized glass, or a glass ceramic and retaining the inner conductor relative to the outer conductor in electrically insulated fashion, wherein a sleeve is assigned to or is formed on the outer conductor and retains or makes it possible to fasten this feedthrough on a housing component that is subject to thermal loading, in particular a functional assembly of the exhaust gas system of a motor vehicle, characterized in that a gap (S P) is formed through the sleeve between the outer lateral surface of the outer conductor and an inner surface of the sleeve in such a way that, in the event of vibrations, or forces that are exerted on the inner conductor and trigger a tilting movement, no damage is done to the outer conductor and the sleeve.
Valuable product or security product with at least one internal electrical circuit, which is formed by at least one semiconductor chip and at least one spiral-shaped antenna conducting track electrically connected to the at least one semiconductor chip, wherein the valuable product or security product further contains core/shell particles containing at least one first chemical substance, wherein the core/shell particles are formed by a shell and a core surrounded by the shell, such that the at least one chemical substance can be released by means of an action on the valuable product or security product, can reach the at least one electrical circuit and there can at least impair the electrical functional capability of the electrical circuit alone or after reaction with at least one second chemical substance, characterized in that the semiconductor chip is placed in the form of a bridge over the spiral-shaped antenna conducting track, such that a first contact point of the semiconductor chip is connected to a first connection contact of the antenna conducting track, and a second connection contact of the semiconductor chip is connected to a second connection contact of the antenna conducting track, and that the impairment or suspension of the electrical functional capability of the electrical circuit, due to the release of the at least one first chemical substance from the core/shell particles, is caused by an electrical short-circuit bridge between the two connection contacts (225, 226) of the antenna conducting track and/or between the contact points (215, 216) of the semiconductor chip.
A method for producing a semiconductor substrate with at least one covered through-substrate via that electrically connects a first substrate side with an opposite second substrate side, comprising the steps of: producing a substrate trench on the first substrate side at a predetermined position of the via; applying a sacrificial cap layer (120, 220, 334) consisting of a cap-layer material, which is thermally stable below a threshold temperature and decomposes at temperatures higher than the threshold temperature, on the first side of the substrate in a patterned manner, thereby completely covering and either partially or completely filling the substrate trench with the cap-layer material, and providing, at a temperature below the threshold temperature, an overcoat layer (122, 226, 336) that covers the sacrificial cap layer on the substrate trench; opening the substrate trench from the second substrate side to transform the trench into a through-substrate via hole; letting the sacrificial cap layer decompose at a temperature above the threshold temperature and removing all decomposition products of the sacrificial cap layer, and applying electrically conductive material in the substrate trench from the second side so as to provide a through-substrate that extends to the second substrate side. producing a substrate trench on the first substrate side at a predetermined position of the via; applying a sacrificial cap layer (120, 220, 334) consisting of a cap-layer material, which is thermally stable below a threshold temperature and decomposes at temperatures higher than the threshold temperature, on the first side of the substrate in a patterned manner, thereby completely covering and either partially or completely filling the substrate trench with the cap-layer material, and providing, at a temperature below the threshold temperature, an overcoat layer (122, 226, 336) that covers the sacrificial cap layer on the substrate trench; opening the substrate trench from the second substrate side to transform the trench into a through-substrate via hole; letting the sacrificial cap layer decompose at a temperature above the threshold temperature and removing all decomposition products of the sacrificial cap layer, and applying electrically conductive material in the substrate trench from the second side so as to provide a through-substrate that extends to the second substrate side.
A method for the production of 2-chloro-3,3,34rifluoropropene comprising the continuous liquid phase reaction of 1,1,2,3-pentachloropropane and anhydrous HF, without the use of a catalyst at a temperature range of 65°C to 175°C; wherein the reaction takes place in one or more reaction vessels, each one in succession converting a portion of the original reactants fed to the lead reaction vessel and wherein the reactions are run in a continuous fashion.