mhurhangee/ep-ind-claims huggingface dataset:
A humanized anti-5T4 antibody comprising heavy chain and light chain variable region complementarity determining regions (CDRs) selected from the group consisting of: a. CDR1, CDR2 and CDR3 amino acid sequences of SEQ ID NO:1 and CDR1, CDR2 and CDR3 amino acid sequences of SEQ ID NO:2; b. CDR1, CDR2 and CDR3 amino acid sequences of SEQ ID NO:5 and CDR1, CDR2 and CDR3 amino acid sequences of SEQ ID NO:6; and c. CDR1, CDR2 and CDR3 amino acid sequences of SEQ ID NO:11 and CDR1, CDR2 and CDR3 amino acid sequences of SEQ ID NO:12; where the CDRs are underlined in the SEQ ID NOs and wherein the antibody comprises at least one engineered cysteine at one or more positions of said antibody selected from heavy chain framework region positions 40, 41 and 89 according to Kabat numbering and light chain framework region positions 40 and 41 according to Kabat numbering. a. CDR1, CDR2 and CDR3 amino acid sequences of SEQ ID NO:1 and CDR1, CDR2 and CDR3 amino acid sequences of SEQ ID NO:2; b. CDR1, CDR2 and CDR3 amino acid sequences of SEQ ID NO:5 and CDR1, CDR2 and CDR3 amino acid sequences of SEQ ID NO:6; and c. CDR1, CDR2 and CDR3 amino acid sequences of SEQ ID NO:11 and CDR1, CDR2 and CDR3 amino acid sequences of SEQ ID NO:12; where the CDRs are underlined in the SEQ ID NOs and wherein the antibody comprises at least one engineered cysteine at one or more positions of said antibody selected from heavy chain framework region positions 40, 41 and 89 according to Kabat numbering and light chain framework region positions 40 and 41 according to Kabat numbering.
A cable transport system comprising: a guide cable; a transfer mechanism (800, 810), wherein the guide cable is fixedly attached to the transfer mechanism (800, 810); and a trolley, wherein the trolley comprises a trolley frame, and one or more grooved wheels mounted to the trolley frame, the grooves of which engage and roll freely upon the guide cable and the transfer mechanism (800, 810), and wherein the guide cable comprises two or more guide cable segments, each guide cable segment having a first support and a second support, and wherein each support is coupled respectively to a corresponding earth-based support structure, and wherein each support is located at a junction of two guide cable segments or at a terminus, and wherein the transfer mechanism (800, 810) supports two guide cable segments or is supported by two guide cable segments at a point near the junction of the two guide cable segments; and characterised by: a derailment safeguard mechanism mounted to the trolley frame which, when positioned to an engaged position, holds a protective pad so as to prevent the guide cable from escaping the grooves of the wheels, wherein the derailment safeguard mechanism is automatically repositioned to a disengaged position as the trolley approaches any transfer mechanism (800, 810). a guide cable; a transfer mechanism (800, 810), wherein the guide cable is fixedly attached to the transfer mechanism (800, 810); and a trolley, wherein the trolley comprises a trolley frame, and one or more grooved wheels mounted to the trolley frame, the grooves of which engage and roll freely upon the guide cable and the transfer mechanism (800, 810), and wherein the guide cable comprises two or more guide cable segments, each guide cable segment having a first support and a second support, and wherein each support is coupled respectively to a corresponding earth-based support structure, and wherein each support is located at a junction of two guide cable segments or at a terminus, and wherein the transfer mechanism (800, 810) supports two guide cable segments or is supported by two guide cable segments at a point near the junction of the two guide cable segments; and characterised by: a derailment safeguard mechanism mounted to the trolley frame which, when positioned to an engaged position, holds a protective pad so as to prevent the guide cable from escaping the grooves of the wheels, wherein the derailment safeguard mechanism is automatically repositioned to a disengaged position as the trolley approaches any transfer mechanism (800, 810).
Connection between a drive shaft of a motor and a driven shaft of a driven apparatus, whereby the drive shaft extends in an axial direction (AA') and the driven shaft parallel to this, at a certain lateral distance from the axial direction (AA'), extends in a parallel axial direction (BB'), whereby the connection is realised by means of a drive gearwheel on the drive shaft and a driven gearwheel on the driven shaft, whereby the drive gearwheel and the driven gearwheel mesh directly with one another, and these gearwheels (6,7) are affixed in a housing, and this housing is on the one hand connected to a housing of the motor, and on the other hand is connected to a housing of the driven apparatus, wherein the drive gearwheel or the driven gearwheel is a ring gear with internal toothing and the remaining gearwheel (7,6) of the connection is a pinion with external toothing, wherein the housing of the connection is equipped with adjustment means with which mutual lateral distance between the driven shaft and the drive shaft can be adjusted and wherein the housing of the connection comprises a first part and a second part, and these parts (20,21) each have a hole (22,23) through which a shaft (2,4) is affixed, either the drive shaft or the driven shaft, characterised in that the aforementioned adjustment means are formed by fasteners with which the first part and the second part of the housing can be detachably fastened to one another.
Mute for recorder consisting of a convex sheet that has removable fixing means to the recorder mouth, said sheet is intended to be inserted in the recorder window, and its thickness is less than the length of the recorder window measured in the direction of the revolution axis of the recorder, the width of said sheet is less than the length of the sharp edge of the revolution bevel, and the length of said sheet is greater than the radial distance between the outer surface of the recorder mouth and the sharp edge of the recorder bevel, and the face of said sheet intended to be facing the recorder mouth is convex from the point of view of said mouth, characterized in that the fixing means are two bands with the form of an arc of circumference and the sheet is in direct contact with the bands and wherein the plane of the sheet and the plane given by the arc of circumference of the bands are parallel.
An imaging apparatus comprising: an imaging unit having a pixel region in which a plurality of pixels is arranged; a readout controller that controls readout of pixel signals from pixels included in the pixel region; and characterized by further comprising: a unit-of-readout controller that controls lines of pixels each as a unit of readout that is set as a part of the pixel region and for which the readout controller sequentially performs the readout of the pixel signal corresponding to a frame image; and a recognition unit that has learned training data for each of the lines of pixels as the units of readout, wherein the recognition unit sequentially performs a recognition process on the pixel signal corresponding to the frame image for each of the lines of pixels as the units of readout, and outputs a recognition result which is a result of the recognition process. an imaging unit having a pixel region in which a plurality of pixels is arranged; a readout controller that controls readout of pixel signals from pixels included in the pixel region; and characterized by further comprising: a unit-of-readout controller that controls lines of pixels each as a unit of readout that is set as a part of the pixel region and for which the readout controller sequentially performs the readout of the pixel signal corresponding to a frame image; and a recognition unit that has learned training data for each of the lines of pixels as the units of readout, wherein the recognition unit sequentially performs a recognition process on the pixel signal corresponding to the frame image for each of the lines of pixels as the units of readout, and outputs a recognition result which is a result of the recognition process. a unit-of-readout controller that controls lines of pixels each as a unit of readout that is set as a part of the pixel region and for which the readout controller sequentially performs the readout of the pixel signal corresponding to a frame image; and a recognition unit that has learned training data for each of the lines of pixels as the units of readout, wherein the recognition unit sequentially performs a recognition process on the pixel signal corresponding to the frame image for each of the lines of pixels as the units of readout, and outputs a recognition result which is a result of the recognition process.
A computerized payment system for initiating electronic payments based on paper cheques, comprising: a paying party terminal including a card reader for receiving a smart card, a keyboard for entry of a PIN code and a processor on the smart card arranged to compare the entered PIN code with data stored on the smart card, wherein the paying party terminal is arranged to authenticate the paying party by comparing the entered PIN code with data stored on the smart card, if the paying party is authenticated as the correct user request the paying party to input cleartext data from a cheque issued by a first bank, at which the paying party has an account, and generate therefrom encoded data using a key which is displayed and written by the paying party on the cheque which is sent or handed to a paid party and a computer associated with said first bank, arranged to: accept, from the paid party, data defining a second bank and an account thereat associated with the paid party; accept, from said paid party, by entering the cleartext data from the cheque and said encoded data, and to validate the cleartext data from the cheque using the encoded data and the key; and arrange a transfer from said first bank to said second bank of the amount specified on said cheque. a paying party terminal including a card reader for receiving a smart card, a keyboard for entry of a PIN code and a processor on the smart card arranged to compare the entered PIN code with data stored on the smart card, wherein the paying party terminal is arranged to authenticate the paying party by comparing the entered PIN code with data stored on the smart card, if the paying party is authenticated as the correct user request the paying party to input cleartext data from a cheque issued by a first bank, at which the paying party has an account, and generate therefrom encoded data using a key which is displayed and written by the paying party on the cheque which is sent or handed to a paid party and a computer associated with said first bank, arranged to: accept, from the paid party, data defining a second bank and an account thereat associated with the paid party; accept, from said paid party, by entering the cleartext data from the cheque and said encoded data, and to validate the cleartext data from the cheque using the encoded data and the key; and arrange a transfer from said first bank to said second bank of the amount specified on said cheque. accept, from the paid party, data defining a second bank and an account thereat associated with the paid party; accept, from said paid party, by entering the cleartext data from the cheque and said encoded data, and to validate the cleartext data from the cheque using the encoded data and the key; and arrange a transfer from said first bank to said second bank of the amount specified on said cheque.
A method comprising: placing an inner surface (120, 420) of an orthopedic augment (100, 200, 300, 400, 500) adjacent to an implant, wherein the inner surface comprises a recessed pocket (130, 230, 330, 430, 432, 434, 530), a rim around at least a portion of the recessed pocket and a port (150, 212, 214, 216, 250, 255, 260, 350, 550, 552) in the rim; and inserting a fixation material into the recessed pocket of the augment via the port, thereby affixing the augment to the implant. placing an inner surface (120, 420) of an orthopedic augment (100, 200, 300, 400, 500) adjacent to an implant, wherein the inner surface comprises a recessed pocket (130, 230, 330, 430, 432, 434, 530), a rim around at least a portion of the recessed pocket and a port (150, 212, 214, 216, 250, 255, 260, 350, 550, 552) in the rim; and inserting a fixation material into the recessed pocket of the augment via the port, thereby affixing the augment to the implant.
A process for the hydrodeoxygenation of feedstock from renewable sources with a hydrodeoxygenation product yield which is more than or equal to 90%, using a supported or bulk catalyst containing an active phase which is a phase containing element(s) used in sulphur-containing form of metals groups, said phase being constituted only by a sulfur-containing group VIB element, the group VIB element being molybdenum, said catalyst in the case of a supported catalyst having a group VIB element content of between 17 and 35% by weight of oxide of said group VIB element in relation to the total mass of the catalyst and also comprising a doping element selected from phosphorus, boron and silicon, deposited on said support, said process being carried out at a temperature of between 120 and 450°C, at a pressure of between 1 MPa and 10 MPa, at an hourly space velocity of between 0.1 h -1 and 10 h -1 and in the presence of a total amount of hydrogen mixed with the charge such that the hydrogen/charge ratio is between 50 and 3000 Nm 3 of hydrogen per m 3 of charge.
A flame-resistant fabric comprising staple yarns comprising intimately blended together, - 35-55 wt. % non-FR cellulosic fibers, - 30-45 wt. % modacrylic fibers, - < 20 wt. % non-flammable fibers, the non-flammable fibers being a blend of (i) para-aramid fibers and (ii) poly(amide-imide) fibers at least a portion of which comprises an energy absorbing additive which absorbs electromagnetic radiation in the wavelength range of 700-2000 nm, to form energy absorbing fibers, wherein - the staple yarns contain < 10 wt. % para-aramid fibers and 5-14 wt. % poly(amide-imide) fibers as the energy absorbing fibers, and - the fabric comprises < 14 wt. % of energy absorbing fibers, and has an arc resistance according to ASTM F1959/F1959M-14e1 of ≥ 0.164 J/cm 2 per g/m 2 (1.33 cal/cm 2 per oz/yd 2) of fabric. - 35-55 wt. % non-FR cellulosic fibers, - 30-45 wt. % modacrylic fibers, - < 20 wt. % non-flammable fibers, the non-flammable fibers being a blend of (i) para-aramid fibers and (ii) poly(amide-imide) fibers at least a portion of which comprises an energy absorbing additive which absorbs electromagnetic radiation in the wavelength range of 700-2000 nm, to form energy absorbing fibers, wherein - the staple yarns contain < 10 wt. % para-aramid fibers and 5-14 wt. % poly(amide-imide) fibers as the energy absorbing fibers, and - the fabric comprises < 14 wt. % of energy absorbing fibers, and has an arc resistance according to ASTM F1959/F1959M-14e1 of ≥ 0.164 J/cm 2 per g/m 2 (1.33 cal/cm 2 per oz/yd 2) of fabric.
A channel resource allocation method, comprising: acquiring, by a first device, scheduling information from an access point; and if the first device is pre-scheduled by the access point according to the scheduling information to receive data from a second device in a first timeslot of a first channel, before a start moment of data transmission time corresponding to the first timeslot of the first channel, sending, by the first device, a contention frame to contend for the first timeslot of the first channel; wherein each timeslot is divided in a part for data transmission and in a part for channel contention and the contention frame is sent by the first device in the part for channel contention of a timeslot and if the first device succeeds in contending, receiving, by the first device, data sent by the second device in the first timeslot of the first channel according to the scheduling information. acquiring, by a first device, scheduling information from an access point; and if the first device is pre-scheduled by the access point according to the scheduling information to receive data from a second device in a first timeslot of a first channel, before a start moment of data transmission time corresponding to the first timeslot of the first channel, sending, by the first device, a contention frame to contend for the first timeslot of the first channel; wherein each timeslot is divided in a part for data transmission and in a part for channel contention and the contention frame is sent by the first device in the part for channel contention of a timeslot and if the first device succeeds in contending, receiving, by the first device, data sent by the second device in the first timeslot of the first channel according to the scheduling information.
A process for the preparation of a compound of formula VIII, the process comprising the steps of: ( a) contacting 4-bromo-1-chloro-2-fluorobenzene with a metallating agent in an aprotic organic solvent to afford an organomagnesium compound, which is reacted with 2-chloro-N-methoxy-N-methylacetamide to afford 2-chloro-1-(4-chloro-3-fluorophenyl)ethanone; (b) contacting II with sodium formate and formic acid in aqueous ethanol to afford 1-(4-chloro-3-fluorophenyl)-2-hydroxyethanone (c) contacting III with a ketoreductase to afford -1-(4-chloro-3-fluorophenyl)ethane-1,2-diol; ( d) contacting IV with a silyl chloride ( R a) 3 SiCl and at least one base in a non-polar aprotic solvent to afford, and subsequently adding sulfonylchloride R b S 2 Cl to afford VI, wherein R a is independently in each occurrence C 1-6 alkyl or phenyl and R b is selected from C 1-4 alkyl or phenyl, optionally substituted with 1 to 3 groups independently selected from C 1-3 alkyl, halogen, nitro, cyano, or C 1-3 alkoxy; (e) contacting 4-(2-(methylsulfonyl)pyrimidin-4-yl)pyridin-2 -one with a strong base in an organic solvent and subsequently adding VI to afford XI; ( f) treating XI with an oxidizing agent to afford I; (g) treating 1-methyl-1H-pyrazol-5-amine with a strong base in an aprotic solvent at reduced temperature and adding the compound of formula I to afford IX; and, (h) contacting IX with a de-silylating agent to afford VIII. ( a) contacting 4-bromo-1-chloro-2-fluorobenzene with a metallating agent in an aprotic organic solvent to afford an organomagnesium compound, which is reacted with 2-chloro-N-methoxy-N-methylacetamide to afford 2-chloro-1-(4-chloro-3-fluorophenyl)ethanone; (b) contacting II with sodium formate and formic acid in aqueous ethanol to afford 1-(4-chloro-3-fluorophenyl)-2-hydroxyethanone (c) contacting III with a ketoreductase to afford -1-(4-chloro-3-fluorophenyl)ethane-1,2-diol; ( d) contacting IV with a silyl chloride ( R a) 3 SiCl and at least one base in a non-polar aprotic solvent to afford, and subsequently adding sulfonylchloride R b S 2 Cl to afford VI, wherein R a is independently in each occurrence C 1-6 alkyl or phenyl and R b is selected from C 1-4 alkyl or phenyl, optionally substituted with 1 to 3 groups independently selected from C 1-3 alkyl, halogen, nitro, cyano, or C 1-3 alkoxy; (e) contacting 4-(2-(methylsulfonyl)pyrimidin-4-yl)pyridin-2 -one with a strong base in an organic solvent and subsequently adding VI to afford XI; ( f) treating XI with an oxidizing agent to afford I; (g) treating 1-methyl-1H-pyrazol-5-amine with a strong base in an aprotic solvent at reduced temperature and adding the compound of formula I to afford IX; and, (h) contacting IX with a de-silylating agent to afford VIII.
Carrier platform for launching or dropping an unmanned missile at/onto a target, characterized by a shaft-like receiving device for receiving at least one missile which is able to be launched at or dropped onto a target, wherein at least one control surface element (2.1) which is able to be reversibly transferred to an operating position and to a non-operating position is arranged or formed on the missile; a transfer device which is assigned to the receiving device and is configured to reversibly transfer the or a missile from a first position, arranged inside the shaft-like receiving device, to a second position, arranged outside the shaft-like receiving device, or vice versa, wherein the or a further transfer device is configured to transfer the at least one control surface element (2.1) from the non-operating position to the operating position when the or a missile is transferred from the first position to the second position, and the or the further transfer device is configured to transfer the at least one control surface element (2.1) from the operating position to the non-operating position when the or a missile is transferred from the second position to the first position. the or a further transfer device is configured to transfer the at least one control surface element (2.1) from the non-operating position to the operating position when the or a missile is transferred from the first position to the second position, and the or the further transfer device is configured to transfer the at least one control surface element (2.1) from the operating position to the non-operating position when the or a missile is transferred from the second position to the first position.
A method of Fibre Channel over Ethernet (FCoE) communication, comprising: providing two or more FCoE forwarders (FCFs) for each of two or more fabrics; representing media access control addresses of the two or more FCoE forwarders (FCFs) with a single MAC address per fabric; receiving an FCoE frame addressed with the single MAC address; wherein the single MAC address assigned for each fabric comprises a virtual FC-MAP-MAC (vFC-MAP-MAC) address for a virtual forwarder (vFCF) of each respective fabric; in the absence of a communication failure with any of the two or more FCFs, forwarding the FCoE frame to a first FCF of the two or more FCFs; and after the occurrence of a communication failure with any of the two or more FCFs, forwarding the FCoE frame to a second FCF of the two or more FCFs. providing two or more FCoE forwarders (FCFs) for each of two or more fabrics; representing media access control addresses of the two or more FCoE forwarders (FCFs) with a single MAC address per fabric; receiving an FCoE frame addressed with the single MAC address; wherein the single MAC address assigned for each fabric comprises a virtual FC-MAP-MAC (vFC-MAP-MAC) address for a virtual forwarder (vFCF) of each respective fabric; in the absence of a communication failure with any of the two or more FCFs, forwarding the FCoE frame to a first FCF of the two or more FCFs; and after the occurrence of a communication failure with any of the two or more FCFs, forwarding the FCoE frame to a second FCF of the two or more FCFs.