mhurhangee/ep-ind-claims huggingface dataset:
A fastener (2, 102) for securing a first component (8, 108) to a second component (4, 104), the fastener comprising:- (i) a body (10, 110) having a bore (24, 26, 124) therein adapted to receive a threaded bolt (6, 106) extending from a first component (8, 108), wherein the bore (24, 26, 124) extends from at least a first end of said body (10, 110); (ii) a flange (34, 134) extending from said body for engaging a first side (36, 136) of a second component (4, 104); (iii) a plurality of resilient first engaging members (56, 156) extending from said body, wherein said first engaging members are adapted to allow insertion of said bolt into the bore from said first end of said body and to engage a thread of said bolt to resist removal of said bolt from said bore; (iv) a plurality of resilient second engaging members (44, 144) extending from said body and adapted to resiliently deform towards said body portion to enable said second engaging members to pass in a first direction through an aperture (46, 146) in the second component (4, 104), and to resist removal of said fastener from the second component in a second direction, opposite to said first direction; and characterized by (v) a plurality of reinforcing members (66, 166) extending from said body, wherein each said reinforcing member is adapted to engage a respective one of said second engaging members, as a result of forces urging said second component towards said first component, to resist flexing of said second engaging members away from said body. (i) a body (10, 110) having a bore (24, 26, 124) therein adapted to receive a threaded bolt (6, 106) extending from a first component (8, 108), wherein the bore (24, 26, 124) extends from at least a first end of said body (10, 110); (ii) a flange (34, 134) extending from said body for engaging a first side (36, 136) of a second component (4, 104); (iii) a plurality of resilient first engaging members (56, 156) extending from said body, wherein said first engaging members are adapted to allow insertion of said bolt into the bore from said first end of said body and to engage a thread of said bolt to resist removal of said bolt from said bore; (iv) a plurality of resilient second engaging members (44, 144) extending from said body and adapted to resiliently deform towards said body portion to enable said second engaging members to pass in a first direction through an aperture (46, 146) in the second component (4, 104), and to resist removal of said fastener from the second component in a second direction, opposite to said first direction; and characterized by (v) a plurality of reinforcing members (66, 166) extending from said body, wherein each said reinforcing member is adapted to engage a respective one of said second engaging members, as a result of forces urging said second component towards said first component, to resist flexing of said second engaging members away from said body.
Inhaler for horses, comprising a cap-like mask which can be pulled over the mouth and nostrils of a horse, and, arranged inside the mask, devices for generating an aerosol for the horse to inhale under the mask, the devices for generating the aerosol having a nebulizer unit with a rechargeable battery, an ultrasonic atomizer and a storage container for liquid that is to be atomized, characterized in that the devices for generating the aerosol can be coupled to the inner side of a bottom of the mask opposite the open cap side and can be uncoupled from this bottom. the devices for generating the aerosol having a nebulizer unit with a rechargeable battery, an ultrasonic atomizer and a storage container for liquid that is to be atomized, characterized in that the devices for generating the aerosol can be coupled to the inner side of a bottom of the mask opposite the open cap side and can be uncoupled from this bottom.
A method for testing the safety of a humanized non-IgG1 anti-beta amyloid antibody, wherein the method comprises: a. incubating microglia cells with neurotoxic amyloid-beta 1-42 (Aβ1-42) oligomers and the humanized non-IgG1 anti-beta amyloid antibody; and b. measuring p38 mitogen-activated protein kinase (p38 MAP kinase) activation in microglia cells, wherein activation is measured in terms of the level of phosphorylated p38 MAP kinase, wherein an intermediate level of p38 MAP kinase activation in microglia cells indicates anti-beta amyloid antibody-mediated neuroprotection without generation of a pathological inflammatory state, and wherein an intermediate level of p38 MAP kinase activation in microglia cells is defined as being when: i) the activation of p38 MAP kinase in microglia cells is 5-55% above p38 MAP kinase activation in microglia cells in the presence of said beta amyloid oligomers but the absence of the humanized non-IgG1 anti-beta amyloid antibody, and ii) the p38 MAP kinase activation in microglia in the presence of beta amyloid is increased by 5-55% less than p38 MAP kinase is activated in the presence of an IgG1 isotype anti-beta amyloid antibody at the same concentration and with the same Kd for beta amyloid binding as the humanized non-IgG1 anti-beta amyloid antibody. a. incubating microglia cells with neurotoxic amyloid-beta 1-42 (Aβ1-42) oligomers and the humanized non-IgG1 anti-beta amyloid antibody; and b. measuring p38 mitogen-activated protein kinase (p38 MAP kinase) activation in microglia cells, wherein activation is measured in terms of the level of phosphorylated p38 MAP kinase, i) the activation of p38 MAP kinase in microglia cells is 5-55% above p38 MAP kinase activation in microglia cells in the presence of said beta amyloid oligomers but the absence of the humanized non-IgG1 anti-beta amyloid antibody, and ii) the p38 MAP kinase activation in microglia in the presence of beta amyloid is increased by 5-55% less than p38 MAP kinase is activated in the presence of an IgG1 isotype anti-beta amyloid antibody at the same concentration and with the same Kd for beta amyloid binding as the humanized non-IgG1 anti-beta amyloid antibody.
A method of using a perforating gun with a degradable internal support structure housed in a tubular carrier by deploying the perforating gun into a well and performing a perforating application in the well, said performing includes at least partially deforming components of the support system; characterised by: employing a break-up treatment fluid in the well to dissolve remaining components of the support system and leave the carrier substantially free therefrom; and flowing a fluid through the component-free tubular carrier device. employing a break-up treatment fluid in the well to dissolve remaining components of the support system and leave the carrier substantially free therefrom; and flowing a fluid through the component-free tubular carrier device.
A heating plate for a hair styling appliance, the heating plate having a length a depth and a width, the heating plate comprising a first continuous hair facing surface and a second surface opposite the first surface, the heating plate comprising at least one groove which runs across the width of the heating plate, each groove extends from the second surface towards the first surface and allows the heating plate to flex.
A method for subscribing to a resource in a field of Internet of Things, comprising: receiving, by a service entity, a subscription request for a first object from a first entity; determining, by the service entity, a second object associated with the first object; generating, by the service entity, a subscription at least to the second object; and sending, by the service entity, a subscription response, wherein the subscription response is used to indicate a result of the subscription, wherein the determining the second object associated with the first object comprises: determining whether the first object and the second object are for a same object; or determining whether the first object and the second object belong to a same group; or determining whether an association attribute of the first object comprises the second object; or determining whether an association attribute of the second object comprises the first object; or determining the second object associated with the first object based on an association rule comprised in the subscription request. receiving, by a service entity, a subscription request for a first object from a first entity; determining, by the service entity, a second object associated with the first object; generating, by the service entity, a subscription at least to the second object; and sending, by the service entity, a subscription response, wherein the subscription response is used to indicate a result of the subscription, wherein the determining the second object associated with the first object determining whether the first object and the second object are for a same object; or determining whether the first object and the second object belong to a same group; or determining whether an association attribute of the first object comprises the second object; or determining whether an association attribute of the second object comprises the first object; or determining the second object associated with the first object based on an association rule comprised in the subscription request.
A pharmaceutical formulation comprising - Lipophilic Amyloid beta ligand stilbene and suitable salts thereof, - Ethanol (8% v/v to 25% v/v), - Polyether (10% w/v to 25% w/v), - Ascorbic acid (0.01% w/v to 1.5% w/v), and - Sodium ascorbate (1.5% w/v to 5% w/v). - Lipophilic Amyloid beta ligand stilbene and suitable salts thereof, - Ethanol (8% v/v to 25% v/v), - Polyether (10% w/v to 25% w/v), - Ascorbic acid (0.01% w/v to 1.5% w/v), and - Sodium ascorbate (1.5% w/v to 5% w/v).
Method for transmitting at least one ticker information (ti) via a packet-oriented network, such as a LAN, for example, with at least one multimedia data stream (mmd) signaled by a network protocol to terminals (E, E) of a multimedia system, - wherein transmission parameters for the transmission of ticker information (ti) and transmission parameters for at least one multimedia data stream (mmd) for a session are transmitted to at least one terminal, - wherein, by means of the transmission parameters for the transmission of the ticker information (ti) at least one transmission protocol and at least one payload type are specified, and at least one source information is inserted, which displays the source of ticket information (ti), - wherein the transmission parameters for the transmission of the ticker information (ti) during the signaling of the transmission parameters are transmitted for the at least one multimedia data stream (mmd) for a session, characterized in that, for the playback of the ticker information (ti), in the display devices associated with the terminals (E, E) of the network, formatting information and/or display information adjusting the ticker information (ti) to the display device is inserted, in addition. - wherein transmission parameters for the transmission of ticker information (ti) and transmission parameters for at least one multimedia data stream (mmd) for a session are transmitted to at least one terminal, - wherein, by means of the transmission parameters for the transmission of the ticker information (ti) at least one transmission protocol and at least one payload type are specified, and at least one source information is inserted, which displays the source of ticket information (ti), - wherein the transmission parameters for the transmission of the ticker information (ti) during the signaling of the transmission parameters are transmitted for the at least one multimedia data stream (mmd) for a session,
A heat exchanger comprising: a housing; a fluid flow conduit located within a cavity formed in the housing, the fluid flow conduit including an outer tube located adjacent to an inner wall of the housing and an inner tube in fluid communication with the outer tube, the inner tube being located between the outer tube and a longitudinal axis of the housing, wherein the outer tube defines a first helix extending generally co-axially with the longitudinal axis and the inner tube defines a second helix also extending generally co-axially with the longitudinal axis; an inlet port located on the housing, the inlet port being in fluid communication with the cavity; an outlet port located on the housing, the outlet port being in fluid communication with the cavity; a flow guide located between the inner tube and the longitudinal axis of the housing, the flow guide being adapted to agitate water flowing between the inlet port and the outlet port, wherein: the housing includes a first section and a second section that are selectively detachable relative to each other; and the flow guide includes two stems which are located at opposing ends of the flow guide, each stem including a first engagement formation for engaging with a corresponding second engagement formation formed in the housing, wherein the flow guide includes an elongate cylindrical member having a textured outer surface. a housing; a fluid flow conduit located within a cavity formed in the housing, the fluid flow conduit including an outer tube located adjacent to an inner wall of the housing and an inner tube in fluid communication with the outer tube, the inner tube being located between the outer tube and a longitudinal axis of the housing, wherein the outer tube defines a first helix extending generally co-axially with the longitudinal axis and the inner tube defines a second helix also extending generally co-axially with the longitudinal axis; an inlet port located on the housing, the inlet port being in fluid communication with the cavity; an outlet port located on the housing, the outlet port being in fluid communication with the cavity; a flow guide located between the inner tube and the longitudinal axis of the housing, the flow guide being adapted to agitate water flowing between the inlet port and the outlet port, wherein: the housing includes a first section and a second section that are selectively detachable relative to each other; and the flow guide includes two stems which are located at opposing ends of the flow guide, each stem including a first engagement formation for engaging with a corresponding second engagement formation formed in the housing, wherein the flow guide includes an elongate cylindrical member having a textured outer surface. the housing includes a first section and a second section that are selectively detachable relative to each other; and the flow guide includes two stems which are located at opposing ends of the flow guide, each stem including a first engagement formation for engaging with a corresponding second engagement formation formed in the housing, wherein the flow guide includes an elongate cylindrical member having a textured outer surface.
An articulating power tool comprising: a housing; a motor located in the housing, the motor including a drive shaft configured for rotation about a first axis; an actuator operatively coupled to the drive shaft configured to convert the rotation of the drive shaft to a reversing angular displacement; a tool holder coupled to the actuator and configured to move in response to movement of the actuator; and an articulator operatively coupled to the housing and to the tool holder, the articulator configured to adjust the tool holder through a range of positions, characterized in that the articulator comprises an articulable joint located at the tool holder. a housing; a motor located in the housing, the motor including a drive shaft configured for rotation about a first axis; an actuator operatively coupled to the drive shaft configured to convert the rotation of the drive shaft to a reversing angular displacement; a tool holder coupled to the actuator and configured to move in response to movement of the actuator; and an articulator operatively coupled to the housing and to the tool holder, the articulator configured to adjust the tool holder through a range of positions, characterized in that the articulator comprises an articulable joint located at the tool holder.
A system for transmission of power from a driving member to a driven member comprising: an electromagnetic clutch including a driving clutch member configured and adapted to rotate in common with an input shaft, and a driven clutch member configured and adapted to rotate in common with an output shaft, wherein the driving clutch member is operatively connected to an electromagnetic actuator for movement between a first position in which the driving clutch member and the driven clutch member are engaged for common rotation and a second position in which the driving clutch member and the driven clutch member are disengaged from one another for relative rotation; and an eddy-current coupling operatively connected to drive the driven clutch member at a rate different from that of the driving clutch member with the driving clutch member in the second position; characterised in that the electromagnetic actuator includes a synchronous generator operatively connected to selectively generate an electromagnetic field to move the driving clutch member into the second position, disengaged from the driven clutch member. an electromagnetic clutch including a driving clutch member configured and adapted to rotate in common with an input shaft, and a driven clutch member configured and adapted to rotate in common with an output shaft, wherein the driving clutch member is operatively connected to an electromagnetic actuator for movement between a first position in which the driving clutch member and the driven clutch member are engaged for common rotation and a second position in which the driving clutch member and the driven clutch member are disengaged from one another for relative rotation; and an eddy-current coupling operatively connected to drive the driven clutch member at a rate different from that of the driving clutch member with the driving clutch member in the second position; characterised in that the electromagnetic actuator includes a synchronous generator operatively connected to selectively generate an electromagnetic field to move the driving clutch member into the second position, disengaged from the driven clutch member.
An endoluminal prosthesis, comprising: a graft (12, 112) having a tubular body and a surface comprising a first biocompatible material, the graft (12, 112) comprising a main lumen disposed therein, a proximal end, and a distal end, and an intermediate section positioned between the proximal end and the distal end, an aperture (42, 142) through a side wall of the intermediate section of the graft (12, 112), the aperture (42, 142) being in fluid communication with the main lumen; a valve arrangement (44, 144) connected to the intermediate section and associated with the aperture (42, 142), the valve arrangement (44, 144) having an open position and a closed position; and a liner comprising a second biocompatible material secured about the intermediate section and surrounding the valve arrangement (44, 144); wherein the valve arrangement (44, 144) comprises a third biocompatible material (45, 145) having corners and being secured to the graft (12, 112) about the aperture (42, 142) at the corners of the valve arrangement (44, 144). a graft (12, 112) having a tubular body and a surface comprising a first biocompatible material, the graft (12, 112) comprising a main lumen disposed therein, a proximal end, and a distal end, and an intermediate section positioned between the proximal end and the distal end, an aperture (42, 142) through a side wall of the intermediate section of the graft (12, 112), the aperture (42, 142) being in fluid communication with the main lumen; a valve arrangement (44, 144) connected to the intermediate section and associated with the aperture (42, 142), the valve arrangement (44, 144) having an open position and a closed position; and a liner comprising a second biocompatible material secured about the intermediate section and surrounding the valve arrangement (44, 144); wherein the valve arrangement (44, 144) comprises a third biocompatible material (45, 145) having corners and being secured to the graft (12, 112) about the aperture (42, 142) at the corners of the valve arrangement (44, 144).
A method of screening for inhibitors of the binding association of PVRIG polypeptide with PVRL2, said method not being performed in humans and said method comprising: a) providing a surface comprising a first ligand protein comprising one of PVRIG polypeptide or PVRL2 polypeptide; b) contacting said surface with a candidate agent under physiological conditions, wherein if said candidate agent binds to said first ligand protein it forms a first binding complex, c) contacting said surface with a second ligand protein comprising the other of PVRIG polypeptide or PVRL2; and d) determining whether said PVRIG polypeptide and said PVRL2 are bound as an indication of whether said candidate agent inhibits said binding association. a) providing a surface comprising a first ligand protein comprising one of PVRIG polypeptide or PVRL2 polypeptide; b) contacting said surface with a candidate agent under physiological conditions, wherein if said candidate agent binds to said first ligand protein it forms a first binding complex, c) contacting said surface with a second ligand protein comprising the other of PVRIG polypeptide or PVRL2; and d) determining whether said PVRIG polypeptide and said PVRL2 are bound as an indication of whether said candidate agent inhibits said binding association.
Use of a compound of formula or of a mixture of compounds of formula wherein: - R 1 is an unsubstituted saturated linear alkyl chain including 11 carbon atoms, q = p = 0 and n = 2, or - R 1 is an unsubstituted saturated linear alkyl chain including 9 carbon atoms, p = n = 1 and q = 3, as insecticide for treating the insects of the family of hemiptera, lepidoptera, diptera and/or coleoptera. - R 1 is an unsubstituted saturated linear alkyl chain including 11 carbon atoms, q = p = 0 and n = 2, or - R 1 is an unsubstituted saturated linear alkyl chain including 9 carbon atoms, p = n = 1 and q = 3,
A sponge cake comprising a saccharide consisting of a fructooligosaccharide and a sugar alcohol wherein the fructooligosaccharide is 1-kestose, and a water-soluble polymer which is collagen peptide, wherein the proportion of the fructooligosaccharide in the total saccharide ingredients is 35 to 100% by weight.
Vehicle mounting kit including: - a plate for preparing mechanical parts (3, 4, 5), this plate for preparing mechanical parts (3, 4, 5) being intended for the assembly of different types of vehicle, - a fuel circuit specific to the type of vehicle to be assembled and equipped with a fuel filling pipe, - the fuel circuit being arranged on the plate for preparing mechanical parts, characterized in that the plate for preparing mechanical parts comprises a first means for attaching the filling pipe whose position for holding the pipe relative to the plate is identical for any type of vehicle, and in that the fuel circuit comprises a second attachment means which cooperates with the first attachment means to hold the filling pipe and whose position of this second attachment means is specific to the fuel circuit of the type of vehicle to be assembled. - a plate for preparing mechanical parts (3, 4, 5), this plate for preparing mechanical parts (3, 4, 5) being intended for the assembly of different types of vehicle, - a fuel circuit specific to the type of vehicle to be assembled and equipped with a fuel filling pipe, - the fuel circuit being arranged on the plate for preparing mechanical parts, characterized in that the plate for preparing mechanical parts comprises a first means for attaching the filling pipe whose position for holding the pipe relative to the plate is identical for any type of vehicle, and in that the fuel circuit comprises a second attachment means which cooperates with the first attachment means to hold the filling pipe and whose position of this second attachment means is specific to the fuel circuit of the type of vehicle to be assembled.