mhurhangee/ep-ind-claims huggingface dataset:
Clamp having an annularly embodied clamp band, which has two tensioning heads (3, 4) connected to one another by a screw connection, wherein the screw connection has a screw, which has a screw head and an external thread with a thread turn profile and a thread axis, and a mating thread element having an internal thread adapted to the external thread, with at least one thread groove which is bordered by thread flanks and into which the screw can be screwed, wherein a reduction in the internal diameter of the clamp band is caused by the two tensioning heads (3, 4) being moved towards each another using the screw connection, for which purpose the screw is led through one of the tensioning heads and screwed into the mating thread element which is arranged in the other of the tensioning heads, wherein the screw is moved deeper into the mating thread element through a rotation of the screw in the mating thread element and the screw head abuts on the other of the tensioning heads, whereby the two tensioning heads (3, 4) are moved towards each another, characterised in that the external thread has a geometrically determined deformation (17, 17', 17") at a predetermined distance (x) from the screw head, which deformation collides with at least one thread flank during the screwing of the screw into the mating thread element.
A composition for use in treating muscular dystrophy in a subject in need thereof, wherein the composition comprises a recombinant adeno-associated virus (rAAV) AAVrh74.tMCK.hSCGA at a dose of 5×10 13 vg/kg to 2×10 14 vg/kg based on a supercoiled DNA or plasmid as the quantitation standard, and wherein the composition is formulated for a systemic route of administration, and further wherein the rAAV comprises a nucleotide sequence with at least 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% identity to SEQ ID NO: 4 and said nucleotide sequence encodes a protein that retains alpha-sarcoglycan activity.
A hydraulic brake valve system, comprising: a brake actuation handle; a valve housing comprising a brake port, a pressure port, a return port, and a valve actuation end; a valve shaft coupled to the valve actuation end, wherein the valve shaft is comprised at least partially within the valve housing; and an electric actuator coupled to the valve shaft, wherein the electric actuator is configured to move the valve shaft between a shaft on position and a shaft off position in response to movement of the brake actuator handle in electronic communication with the electric actuator, wherein the hydraulic brake valve system is configured to pass hydraulic pressure through at least one of the brake port, the pressure port, or the return port in response to a position of the valve shaft. a brake actuation handle; a valve housing comprising a brake port, a pressure port, a return port, and a valve actuation end; a valve shaft coupled to the valve actuation end, wherein the valve shaft is comprised at least partially within the valve housing; and an electric actuator coupled to the valve shaft, wherein the electric actuator is configured to move the valve shaft between a shaft on position and a shaft off position in response to movement of the brake actuator handle in electronic communication with the electric actuator, wherein the hydraulic brake valve system is configured to pass hydraulic pressure through at least one of the brake port, the pressure port, or the return port in response to a position of the valve shaft.
A tangential flow filtration, TFF, assembly, comprising: a plurality of stacked processing units (1, 2, 3) that are fluidly connected, wherein each processing unit (1, 2, 3) comprises a cassette holder containing at least one TFF cassette, and wherein the processing units (1, 2, 3) in the assembly are configured for processing in parallel and/or in series; a first channel connected to a feed inlet extending through the plurality of processing units (1, 2, 3); a second channel connected to a retentate outlet extending through the plurality of processing units (1, 2, 3); a permeate channel extending through the plurality of processing units (1, 2, 3); at least one pump or control valve for recirculating retentate through all or part of the assembly; at least one conduit for recirculating retentate; and one or more valves, valves (9, 10), wherein each valve (9, 10) is located on either the first channel or the second channel between two adjacent processing units (1, 2, 3), and wherein the valves (9, 10) alternate between the first channel and second channel for consecutive pairs of adjacent processing units (1, 2, 3); wherein the plurality of processing units (1, 2, 3) are processed in parallel when the valves (9, 10) are open, or in series when the valves (9, 10) are closed. a plurality of stacked processing units (1, 2, 3) that are fluidly connected, wherein each processing unit (1, 2, 3) comprises a cassette holder containing at least one TFF cassette, and wherein the processing units (1, 2, 3) in the assembly are configured for processing in parallel and/or in series; a first channel connected to a feed inlet extending through the plurality of processing units (1, 2, 3); a second channel connected to a retentate outlet extending through the plurality of processing units (1, 2, 3); a permeate channel extending through the plurality of processing units (1, 2, 3); at least one pump or control valve for recirculating retentate through all or part of the assembly; at least one conduit for recirculating retentate; and one or more valves, valves (9, 10), wherein each valve (9, 10) is located on either the first channel or the second channel between two adjacent processing units (1, 2, 3), and wherein the valves (9, 10) alternate between the first channel and second channel for consecutive pairs of adjacent processing units (1, 2, 3); wherein the plurality of processing units (1, 2, 3) are processed in parallel when the valves (9, 10) are open, or in series when the valves (9, 10) are closed.
A liquid hand dishwashing detergent composition comprising 10% to 40% by weight of the composition of a surfactant system, the surfactant system comprising an anionic surfactant and a primary co-surfactant selected from the group consisting of amphoteric surfactant, zwitterionic surfactant and mixtures thereof wherein the anionic surfactant and the primary co-surfactant are in a weight ratio of less than 2.5:1 and wherein the composition further comprises a cyclic diamine of Formula: wherein two of the Rs, are selected from the group consisting of NH2, (C1-C4)NH2 and mixtures thereof and the remaining Rs are independently selected from H, linear or branched alkyl or alkenyl having from 1 to 10 carbon atoms.
A system for perforating a formation intersected by a wellbore, comprising: a carrier; and a plurality of shaped charges positioned along charge holder in the carrier; and the system characterised by: a plurality of pellets at least partially of a reactant composite material positioned in the charge holder and interleaved with plurality of shaped charges, the reactant composite material being oxygen overbalanced sufficient to react with a carbon released upon detonation of the plurality of shaped charges, the plurality of pellets being configured to disintegrate upon detonation of the shaped charges and release the oxygen; respective axial spaces separating adjacent shaped charges of the plurality of shaped charges from one another, each axial space including at least one pellet of the plurality of pellets; and a detonator cord configured to detonate the plurality of shaped charges. a carrier; and a plurality of shaped charges positioned along charge holder in the carrier; and the system characterised by: a plurality of pellets at least partially of a reactant composite material positioned in the charge holder and interleaved with plurality of shaped charges, the reactant composite material being oxygen overbalanced sufficient to react with a carbon released upon detonation of the plurality of shaped charges, the plurality of pellets being configured to disintegrate upon detonation of the shaped charges and release the oxygen; respective axial spaces separating adjacent shaped charges of the plurality of shaped charges from one another, each axial space including at least one pellet of the plurality of pellets; and a detonator cord configured to detonate the plurality of shaped charges.
A slider cover for a slide fastener, comprising: an upper member (51, 61, 71, 81) and a lower member (52, 62, 72, 82) which are spaced apart from each other in an upward and downward direction and arranged in parallel to each other; and a connecting post (53, 63, 73, 83) connecting the upper member with the lower member, wherein the upper member comprises a receiving portion (54, 64, 74, 84) configured to receive at least a part of an upper blade of a slider, characterized in that the receiving portion (54, 64, 74, 84) is a hole portion penetrating through upper and lower surfaces of the upper member (51, 61, 71, 81). an upper member (51, 61, 71, 81) and a lower member (52, 62, 72, 82) which are spaced apart from each other in an upward and downward direction and arranged in parallel to each other; and a connecting post (53, 63, 73, 83) connecting the upper member with the lower member, wherein the upper member comprises a receiving portion (54, 64, 74, 84) configured to receive at least a part of an upper blade of a slider, characterized in that the receiving portion (54, 64, 74, 84) is a hole portion penetrating through upper and lower surfaces of the upper member (51, 61, 71, 81).
A system comprising: a canister (110; 204) comprising a canister fitment; a carbonation tank configured to receive gas from the canister; a canister connection apparatus comprising: a receiver fitment comprising a valve opening component configured to open a valve of the canister, the receiver fitment being configured to connect to the canister fitment, wherein the receiver fitment is further configured to seal and cover the canister fitment; the receiver fitment further comprising a carbonator throttle configured to restrict a flow of gas from the canister, after release by the valve opening component, to a reduced flow rate to prevent over pressurization of the carbonation tank; and the system further comprising a controller in communication with the receiver fitment and the carbonation tank and configured to control the carbonator throttle. a canister (110; 204) comprising a canister fitment; a carbonation tank configured to receive gas from the canister; a canister connection apparatus comprising: a receiver fitment comprising a valve opening component configured to open a valve of the canister, the receiver fitment being configured to connect to the canister fitment, wherein the receiver fitment is further configured to seal and cover the canister fitment; the receiver fitment further comprising a carbonator throttle configured to restrict a flow of gas from the canister, after release by the valve opening component, to a reduced flow rate to prevent over pressurization of the carbonation tank; and a receiver fitment comprising a valve opening component configured to open a valve of the canister, the receiver fitment being configured to connect to the canister fitment, wherein the receiver fitment is further configured to seal and cover the canister fitment; the receiver fitment further comprising a carbonator throttle configured to restrict a flow of gas from the canister, after release by the valve opening component, to a reduced flow rate to prevent over pressurization of the carbonation tank; and the system further comprising a controller in communication with the receiver fitment and the carbonation tank and configured to control the carbonator throttle.
Tunnel structure constructed in an open design with at least one concrete body whose outer side is covered with a non-water-penetrable sealing system, which at least comprises: - an underlying, secondary sealing layer which is formed from sealing membranes which each consist of at least one textile layer which is filled with a swellable bentonite, and - a primary sealing layer which is formed by a plastic sealing membrane which is laid on the secondary sealing layer, characterized - in that the secondary sealing layer is formed from sealing membranes which are laid in an overlapping manner, and - in that the sealing layers (21, 22) are covered with a drainage layer which is formed as a pressure-stable, water-permeable body. - an underlying, secondary sealing layer which is formed from sealing membranes which each consist of at least one textile layer which is filled with a swellable bentonite, and - a primary sealing layer which is formed by a plastic sealing membrane which is laid on the secondary sealing layer, characterized - in that the secondary sealing layer is formed from sealing membranes which are laid in an overlapping manner, and - in that the sealing layers (21, 22) are covered with a drainage layer which is formed as a pressure-stable, water-permeable body.
A polyamide resin composition for foam molding comprising: 40 to 70 parts by mass of a crystalline polyamide resin; 5 to 15 parts by mass of a non-crystalline polyamide resin; 15 to 50 parts by mass of an inorganic reinforcing material; 0.1 to 10 parts by mass of an elastomer; and 0.5 to 15 parts by mass of a copolymer having a functional group that reacts with a terminal group of the polyamide resin, wherein a total amount of the crystalline polyamide resin, the non-crystalline polyamide resin, the inorganic reinforcing material, the elastomer, and the copolymer having a functional group that reacts with a terminal group of the polyamide resin is 100 parts by mass. 40 to 70 parts by mass of a crystalline polyamide resin; 5 to 15 parts by mass of a non-crystalline polyamide resin; 15 to 50 parts by mass of an inorganic reinforcing material; 0.1 to 10 parts by mass of an elastomer; and 0.5 to 15 parts by mass of a copolymer having a functional group that reacts with a terminal group of the polyamide resin, wherein a total amount of the crystalline polyamide resin, the non-crystalline polyamide resin, the inorganic reinforcing material, the elastomer, and the copolymer having a functional group that reacts with a terminal group of the polyamide resin is 100 parts by mass.
Method of preparing compound of formula (I-A) or (I-B) comprising the step of reacting compound of formula with Al(CH 3) 3 in the presence of a Cu(l) salt and chiral compound of formula (II-A) or (II-B) followed by a ester hydrolysis and decarboxylation by heating to a temperature of 100-190 °C, particularly 150-190°C; wherein R 5 represents either a linear or branched completely saturated C 6 - 25 -alkyl group or a linear or branched C 6 - 25 -alkyl group comprising at least one carbon-carbon double bond; R 1, R 3 and R 4 are independently from each other hydrogen or methyl groups; R 2 represents hydrogen or a phenol protecting group; R' and R are independently from each other a hydrocarbyl group with 1 to 12 carbon atoms, which optionally is substituted by OR 6, or form together a C 4 - 6 -alkylene group which optionally comprises a functional group which is selected from the group consisting of wherein R"' and R 7 are independently from each other a C 1-4 -alkyl group; and R 6 is a methyl or ethyl group or tert. -butyl group; with the proviso that for the preparation of compound (I-A) the compound (II-A) is used and that for the preparation of compound (I-B) the compound (II-B) is used. wherein R 5 represents either a linear or branched completely saturated C 6 - 25 -alkyl group or a linear or branched C 6 - 25 -alkyl group comprising at least one carbon-carbon double bond; R 1, R 3 and R 4 are independently from each other hydrogen or methyl groups; R 2 represents hydrogen or a phenol protecting group; R' and R are independently from each other a hydrocarbyl group with 1 to 12 carbon atoms, which optionally is substituted by OR 6, or form together a C 4 - 6 -alkylene group which optionally comprises a functional group which is selected from the group consisting of wherein R"' and R 7 are independently from each other a C 1-4 -alkyl group; and R 6 is a methyl or ethyl group or tert. -butyl group;
A trap including: a bait, a support, and an elastic band, wherein the trap is configured such that in a set state the support supports the elastic band in an expanded state, and characterised in that the bait is configured to maintain the support to support the elastic band such that removal, consumption or destruction of the bait by an animal allows the support to collapse to either: cause the elastic band to contract around the animal to kill the animal; or cause the elastic band to drive a kill mechanism to kill the animal. a bait, a support, and an elastic band, wherein the trap is configured such that in a set state the support supports the elastic band in an expanded state, and characterised in that the bait is configured to maintain the support to support the elastic band such that removal, consumption or destruction of the bait by an animal allows the support to collapse to either: cause the elastic band to contract around the animal to kill the animal; or cause the elastic band to drive a kill mechanism to kill the animal.
A method of generating a nucleic acid library comprising a plurality of nucleic acids, said method comprising: contacting a nucleic acid sample to primers, a strand displacing polymerase, and a ddNTP coupled with an affinity conjugate, hybridizing said primers to said nucleic acid sample and generating a plurality of amplified nucleic acids from said nucleic acid sample using said strand displacing polymerase, and contacting said nucleic acid sample to a binding molecule to said affinity conjugate, wherein said plurality of amplified nucleic acids has a length of at least 200 bp, wherein said primers comprise a random sequence polynucleotide, and wherein said plurality of amplified nucleic acids comprises random 3' ends. contacting a nucleic acid sample to primers, a strand displacing polymerase, and a ddNTP coupled with an affinity conjugate, hybridizing said primers to said nucleic acid sample and generating a plurality of amplified nucleic acids from said nucleic acid sample using said strand displacing polymerase, and contacting said nucleic acid sample to a binding molecule to said affinity conjugate,
Arrangement having a fastening element which is screwable into a component (11, 12) with a screw thread and a screw head, having a sealing element for inserting into a parting line between a sealing surface of the arrangement and a counterface formed by the component (11, 12), whereby the sealing element is braced by tightening the screw connection between the sealing surface and the counterface, wherein a cap covering the screw head is provided, wherein the screw head has an external thread and the cap has an internal thread, wherein the external thread and the internal thread engage in one another and enable a screwing of the cap onto the screw head, and wherein the sealing face of the arrangement is formed by an underside of the cap facing toward the component (11, 12), characterised in that the sealing element is formed electrically non-conductive, and in that an electrically conductive element is embedded in the sealing element, in particular a thin wire bent into a bow shape, which creates an electrically conductive connection between the exterior of the sealing element and the interior of the sealing element facing toward the fastening element.
Universal closure cap for closing a plug connector, wherein the plug connector comprises at least one coding lug and at least one latching hook, comprising: a plug connector receptacle for receiving the plug connector in a plugged state, wherein the plug connector receptacle comprises an axial groove and at least one latching hook receptacle, wherein at least one of the at least one axial groove has a groove length in parallel with a central axis of the plug connector receptacle, and a groove width, wherein the at least one latching hook receptacle is configured to come into engagement with at least one of the at least one latching hook, in the plugged state, and wherein the at least one axial groove is configured to receive at least one of the at least one coding lug, in the plugged state, wherein the groove width corresponds to a circular arc with respect to the central axis having a central angle of at least approximately 30° and at most approximately 160°, wherein the closure cap is configured such that a plurality of different plug connectors ca be individually closed by means of the closure cap. a plug connector receptacle for receiving the plug connector in a plugged state, wherein the plug connector receptacle comprises an axial groove and at least one latching hook receptacle, wherein at least one of the at least one axial groove has a groove length in parallel with a central axis of the plug connector receptacle, and a groove width, wherein the at least one latching hook receptacle is configured to come into engagement with at least one of the at least one latching hook, in the plugged state, and wherein the at least one axial groove is configured to receive at least one of the at least one coding lug, in the plugged state, wherein the groove width corresponds to a circular arc with respect to the central axis having a central angle of at least approximately 30° and at most approximately 160°, wherein the closure cap is configured such that a plurality of different plug connectors ca be individually closed by means of the closure cap.
A toggle for rigging of a boat or a crane, comprising a) a first coupling end i. comprising a first coupling means providing a first axis of engagement; and b) a second coupling end i. comprising a second coupling means providing a second axis of engagement; c) the first and the second coupling means (110, 210) arranged a distance apart from each other; d) a closed-loop connecting means i. made from a fibre-reinforced plastic, ii. comprising a plurality of fibrous layers laying one above the other in a local stacking direction (v), and iii. wherein between the first and the second coupling means (110, 210) the closed-loop connecting means is twisted such that the local stacking direction (v) rotates approximately 90° about the local longitudinal direction (w) of the closed-loop connecting means; e) the closed-loop connecting means loops about the first axis of engagement and f) the closed-loop connecting means loops about the second axis of engagement, g) thereby mechanically interconnecting the first coupling means with the second coupling means. a) a first coupling end i. comprising a first coupling means providing a first axis of engagement; and i. comprising a first coupling means providing a first axis of engagement; and b) a second coupling end i. comprising a second coupling means providing a second axis of engagement; i. comprising a second coupling means providing a second axis of engagement; c) the first and the second coupling means (110, 210) arranged a distance apart from each other; d) a closed-loop connecting means i. made from a fibre-reinforced plastic, ii. comprising a plurality of fibrous layers laying one above the other in a local stacking direction (v), and iii. wherein between the first and the second coupling means (110, 210) the closed-loop connecting means is twisted such that the local stacking direction (v) rotates approximately 90° about the local longitudinal direction (w) of the closed-loop connecting means; i. made from a fibre-reinforced plastic, ii. comprising a plurality of fibrous layers laying one above the other in a local stacking direction (v), and iii. wherein between the first and the second coupling means (110, 210) the closed-loop connecting means is twisted such that the local stacking direction (v) rotates approximately 90° about the local longitudinal direction (w) of the closed-loop connecting means; e) the closed-loop connecting means loops about the first axis of engagement and f) the closed-loop connecting means loops about the second axis of engagement, g) thereby mechanically interconnecting the first coupling means with the second coupling means.