A method of loading fuel in multiple reactor cores (710, 720, 730, 810, 820, 830, 840, 910, 920, 930, 940, 970) of a multi-modular power plant, the multiple reactor cores (710, 720, 730, 810, 820, 830, 840, 910, 920, 930, 940, 970) comprising a first reactor core (710, 810, 910) including first fuel assemblies, a second reactor core (720, 820, 920) including second fuel assemblies and a third reactor core including third fuel assemblies, the multiple reactor cores being associated with a plurality of fuel cycles, the method comprising: providing a first fuel configuration including loading the first reactor core (710, 810, 910) with a fresh first fuel assembly (712, 722, 732, 812, 822, 832) from a first batch of fuel, wherein the first batch of fuel includes fresh fuel; loading the first reactor core (710, 810, 910) with a first partially spent fuel assembly (714, 724, 734, 814, 824, 844) from a second batch of fuel, wherein the second batch of fuel includes fuel that has been partially spent during a previous fuel cycle; loading the second reactor core (720, 820, 920) with a fresh second fuel assembly (712, 722, 732, 812, 822, 832) from the first batch of fuel; and loading the second reactor core (720, 820, 920) with a second partially spent fuel assembly (714, 724, 734, 814, 824, 844) from the second batch of fuel; loading the third reactor core with a fresh third fuel assembly from the first batch of fuel; and loading the third reactor core with a third partially spent fuel assembly from the second batch of fuel; operating the first reactor core, the second reactor core, and the third reactor core with the first fuel configuration during a first fuel cycle; and after operating the first reactor core, the second reactor core, and the third reactor core with the first fuel configuration during the first fuel cycle, and before a second fuel cycle, providing a second fuel configuration including loading the second reactor core (720, 820, 920) with another fresh fuel assembly from the first batch of fuel; and loading the second reactor core (720, 820, 920) with the first fuel assembly from the first batch of fuel, wherein the first fuel assembly is partially spent after operating the first reactor core in the first fuel configuration during the first fuel cycle (712, 722, 732, 812, 822, 832). providing a first fuel configuration including loading the first reactor core (710, 810, 910) with a fresh first fuel assembly (712, 722, 732, 812, 822, 832) from a first batch of fuel, wherein the first batch of fuel includes fresh fuel; loading the first reactor core (710, 810, 910) with a first partially spent fuel assembly (714, 724, 734, 814, 824, 844) from a second batch of fuel, wherein the second batch of fuel includes fuel that has been partially spent during a previous fuel cycle; loading the second reactor core (720, 820, 920) with a fresh second fuel assembly (712, 722, 732, 812, 822, 832) from the first batch of fuel; and loading the second reactor core (720, 820, 920) with a second partially spent fuel assembly (714, 724, 734, 814, 824, 844) from the second batch of fuel; loading the third reactor core with a fresh third fuel assembly from the first batch of fuel; and loading the third reactor core with a third partially spent fuel assembly from the second batch of fuel; loading the first reactor core (710, 810, 910) with a fresh first fuel assembly (712, 722, 732, 812, 822, 832) from a first batch of fuel, wherein the first batch of fuel includes fresh fuel; loading the first reactor core (710, 810, 910) with a first partially spent fuel assembly (714, 724, 734, 814, 824, 844) from a second batch of fuel, wherein the second batch of fuel includes fuel that has been partially spent during a previous fuel cycle; loading the second reactor core (720, 820, 920) with a fresh second fuel assembly (712, 722, 732, 812, 822, 832) from the first batch of fuel; and loading the second reactor core (720, 820, 920) with a second partially spent fuel assembly (714, 724, 734, 814, 824, 844) from the second batch of fuel; loading the third reactor core with a fresh third fuel assembly from the first batch of fuel; and loading the third reactor core with a third partially spent fuel assembly from the second batch of fuel; operating the first reactor core, the second reactor core, and the third reactor core with the first fuel configuration during a first fuel cycle; and after operating the first reactor core, the second reactor core, and the third reactor core with the first fuel configuration during the first fuel cycle, and before a second fuel cycle, providing a second fuel configuration including loading the second reactor core (720, 820, 920) with another fresh fuel assembly from the first batch of fuel; and loading the second reactor core (720, 820, 920) with the first fuel assembly from the first batch of fuel, wherein the first fuel assembly is partially spent after operating the first reactor core in the first fuel configuration during the first fuel cycle (712, 722, 732, 812, 822, 832). loading the second reactor core (720, 820, 920) with another fresh fuel assembly from the first batch of fuel; and loading the second reactor core (720, 820, 920) with the first fuel assembly from the first batch of fuel, wherein the first fuel assembly is partially spent after operating the first reactor core in the first fuel configuration during the first fuel cycle (712, 722, 732, 812, 822, 832).