A toilet paper roll manufacturing method comprising: a first step of pulling out base paper from each of multiple base paper rolls; a second step of introducing multiple sheets of the base paper to a lamination unit, laminating the multiple sheets of the base paper, and forming 4-ply toilet paper; a third step of drying the 4-ply toilet paper; and a fourth step of rolling up the 4-ply toilet paper and manufacturing a 4-ply toilet paper roll, wherein the second step comprises: a fifth step of separating the multiple sheets of the base paper introduced to the lamination unit into a first 1-ply paper sheet, a second 1-ply paper sheet, a third 1-ply paper sheet, and a fourth 1-ply paper sheet, positioning a rear surface of the first 1-ply paper sheet and a front surface of the second 1-ply paper sheet to face each other, positioning a rear surface of the second 1-ply paper sheet and a front surface of the third 1-ply paper sheet to face each other, and positioning a rear surface of the third 1-ply paper sheet and a front surface of the fourth 1-ply paper sheet to face each other; a sixth step of operating a first sprayer to spray a bonding liquid toward the rear surface of the first 1-ply paper sheet and the front surface of the second 1-ply paper sheet; a seventh step of operating a second sprayer to spray the bonding liquid toward the rear surface of the second 1-ply paper sheet and the front surface of the third 1-ply paper sheet; an eighth step of operating a third sprayer to spray the bonding liquid toward the rear surface of the third 1-ply paper sheet and the front surface of the fourth 1-ply paper sheet; and a ninth step of operating a pressure roller to stack the first 1-ply paper sheet, the second 1-ply paper sheet, the third 1-ply paper sheet, and the fourth 1-ply paper sheet and to apply pressure to permeate the bonding liquid into the first to fourth 1-ply paper sheets. a first step of pulling out base paper from each of multiple base paper rolls; a second step of introducing multiple sheets of the base paper to a lamination unit, laminating the multiple sheets of the base paper, and forming 4-ply toilet paper; a third step of drying the 4-ply toilet paper; and a fourth step of rolling up the 4-ply toilet paper and manufacturing a 4-ply toilet paper roll, wherein the second step comprises: a fifth step of separating the multiple sheets of the base paper introduced to the lamination unit into a first 1-ply paper sheet, a second 1-ply paper sheet, a third 1-ply paper sheet, and a fourth 1-ply paper sheet, positioning a rear surface of the first 1-ply paper sheet and a front surface of the second 1-ply paper sheet to face each other, positioning a rear surface of the second 1-ply paper sheet and a front surface of the third 1-ply paper sheet to face each other, and positioning a rear surface of the third 1-ply paper sheet and a front surface of the fourth 1-ply paper sheet to face each other; a sixth step of operating a first sprayer to spray a bonding liquid toward the rear surface of the first 1-ply paper sheet and the front surface of the second 1-ply paper sheet; a seventh step of operating a second sprayer to spray the bonding liquid toward the rear surface of the second 1-ply paper sheet and the front surface of the third 1-ply paper sheet; an eighth step of operating a third sprayer to spray the bonding liquid toward the rear surface of the third 1-ply paper sheet and the front surface of the fourth 1-ply paper sheet; and a ninth step of operating a pressure roller to stack the first 1-ply paper sheet, the second 1-ply paper sheet, the third 1-ply paper sheet, and the fourth 1-ply paper sheet and to apply pressure to permeate the bonding liquid into the first to fourth 1-ply paper sheets. a fifth step of separating the multiple sheets of the base paper introduced to the lamination unit into a first 1-ply paper sheet, a second 1-ply paper sheet, a third 1-ply paper sheet, and a fourth 1-ply paper sheet, positioning a rear surface of the first 1-ply paper sheet and a front surface of the second 1-ply paper sheet to face each other, positioning a rear surface of the second 1-ply paper sheet and a front surface of the third 1-ply paper sheet to face each other, and positioning a rear surface of the third 1-ply paper sheet and a front surface of the fourth 1-ply paper sheet to face each other; a sixth step of operating a first sprayer to spray a bonding liquid toward the rear surface of the first 1-ply paper sheet and the front surface of the second 1-ply paper sheet; a seventh step of operating a second sprayer to spray the bonding liquid toward the rear surface of the second 1-ply paper sheet and the front surface of the third 1-ply paper sheet; an eighth step of operating a third sprayer to spray the bonding liquid toward the rear surface of the third 1-ply paper sheet and the front surface of the fourth 1-ply paper sheet; and a ninth step of operating a pressure roller to stack the first 1-ply paper sheet, the second 1-ply paper sheet, the third 1-ply paper sheet, and the fourth 1-ply paper sheet and to apply pressure to permeate the bonding liquid into the first to fourth 1-ply paper sheets.