mhurhangee/ep-ind-claims huggingface dataset:
A method for producing a polyclonal cell population, said method comprising the steps of: a) transforming a population of host cells with at least one vector comprising at least one copy of a nucleic acid sequence that encodes a component of a polyclonal protein composition, in the presence of adeno-associated virus rep or retroviral integrase, such that preferential integration of the nucleic acid sequence into the genome of each of the host cells takes place at a plurality of locations recognized by the adeno-associated virus rep or integrase, wherein preferential integration means that there is variability in the site(s) at which the nucleic acid sequence integrates such that integration is neither random nor single-site specific, and wherein, after said preferential integration, host cells are not genetically identical due to variability in the number and/or location of the integration site(s); b) subsequently generating from the host cells a first cell population, without clonal selection or production of individual cell lines, capable of producing the component of the polyclonal protein composition; and c) repeating steps (a) and (b) at least once to generate at least a second cell population, wherein the second cell population is capable of producing a different component of the polyclonal protein composition; and d) mixing at least the first cell population and the second cell population, wherein each cell population comprises greater than 10,000 individual cells, to produce a polyclonal cell population capable of producing the polyclonal protein composition. a) transforming a population of host cells with at least one vector comprising at least one copy of a nucleic acid sequence that encodes a component of a polyclonal protein composition, in the presence of adeno-associated virus rep or retroviral integrase, such that preferential integration of the nucleic acid sequence into the genome of each of the host cells takes place at a plurality of locations recognized by the adeno-associated virus rep or integrase, wherein preferential integration means that there is variability in the site(s) at which the nucleic acid sequence integrates such that integration is neither random nor single-site specific, and wherein, after said preferential integration, host cells are not genetically identical due to variability in the number and/or location of the integration site(s); b) subsequently generating from the host cells a first cell population, without clonal selection or production of individual cell lines, capable of producing the component of the polyclonal protein composition; and c) repeating steps (a) and (b) at least once to generate at least a second cell population, wherein the second cell population is capable of producing a different component of the polyclonal protein composition; and d) mixing at least the first cell population and the second cell population, wherein each cell population comprises greater than 10,000 individual cells, to produce a polyclonal cell population capable of producing the polyclonal protein composition.
A power converter for stepping down and converting an AC voltage from an AC power supply to a DC voltage, said power converter comprising: first and second input connections (T1, T2) for inputting output of said AC power supply; a first capacitor and a second capacitor interposed in series on a first electric connection line between said first input connection and said second input connection, in the order first capacitor, second capacitor, from said first input connection; a first diode interposed between the first capacitor and said second capacitor on said first electric connection line so that its forward direction is toward said second input connection; a second diode interposed on a second electric connection line so that its reverse direction is toward said second input connection, said second electric connection line connecting a point between said first capacitor and said first diode on said first electric connection line, and said second input connection; a first output connection for output of said DC voltage, which is connected between said first diode and said second capacitor on said first electric connection line; and a second output connection for output of said DC voltage, which is connected to said second input connection characterized by a third capacitor, one end of which is connected between said first capacitor and said first diode on said first electric connection line, and the other end of which is connected to said second input connection. first and second input connections (T1, T2) for inputting output of said AC power supply; a first capacitor and a second capacitor interposed in series on a first electric connection line between said first input connection and said second input connection, in the order first capacitor, second capacitor, from said first input connection; a first capacitor and a second capacitor interposed in series on a first electric connection line between said first input connection and said second input connection, in the order first capacitor, second capacitor, from said first input connection; a first diode interposed between the first capacitor and said second capacitor on said first electric connection line so that its forward direction is toward said second input connection; a second diode interposed on a second electric connection line so that its reverse direction is toward said second input connection, said second electric connection line connecting a point between said first capacitor and said first diode on said first electric connection line, and said second input connection; a first output connection for output of said DC voltage, which is connected between said first diode and said second capacitor on said first electric connection line; and a second output connection for output of said DC voltage, which is connected to said second input connection characterized by a third capacitor, one end of which is connected between said first capacitor and said first diode on said first electric connection line, and the other end of which is connected to said second input connection.
A method for multi-spectral imagery acquisition and analysis, the method comprising: acquiring multi-spectral aerial images at a pre-selected low resolution; identifying irregularities or regions of interest associated with a desired range of Normalized Difference of Vegetation Index, NDVI, values by automatically performing a preliminary analysis of the low resolution images using blob partitioning on a large scale, wherein the large scale is defined by the pixels per blob used, in real or near real time, and providing an output corresponding thereto; associating GPS data, synchronised with the capturing time of the multi-spectral aerial images, with the detected irregularities; and automatically determining, from said output, whether to perform a second stage of image acquisition at a higher resolution than said pre-selected low resolution and analysis using small scale blob partitioning, wherein the small scale is defined by the pixels per blob used, by determining whether the extent or size of the irregularities meets a pre-selected threshold. acquiring multi-spectral aerial images at a pre-selected low resolution; identifying irregularities or regions of interest associated with a desired range of Normalized Difference of Vegetation Index, NDVI, values by automatically performing a preliminary analysis of the low resolution images using blob partitioning on a large scale, wherein the large scale is defined by the pixels per blob used, in real or near real time, and providing an output corresponding thereto; associating GPS data, synchronised with the capturing time of the multi-spectral aerial images, with the detected irregularities; and automatically determining, from said output, whether to perform a second stage of image acquisition at a higher resolution than said pre-selected low resolution and analysis using small scale blob partitioning, wherein the small scale is defined by the pixels per blob used, by determining whether the extent or size of the irregularities meets a pre-selected threshold.
A method of remote controlling a luminous signalling system in the course of team games played by orally and aurally challenged players according to rules of different sports disciplines under the supervision of a referee, wherein the referee uses a whistle equipped with a radio transmitting device, wherein when the referee blows into the whistle, the whistle generates and radio transmits coded binary signals which are received by an electronic receiving device, wherein the whistle comprises a housing with a mouthpiece having an inlet for air blown into the mouthpiece, wherein, inside the housing, the whistle further comprises a blow sensor, which is located downstream the mouthpiece, a microprocessor, a radio transmitter coupled to a transmitting antenna and a battery for powering the microprocessor and the radio transmitter, wherein the blow sensor comprises a rotor and a ferreed relay, wherein the rotor is equipped with a N-S magnet, wherein, when the rotor is activated by air blowed into the whistle, the rotation of the N-S magnet installed in the rotor causes the ferreed relay to generate a series of pulse signals, which are input to the microprocessor, wherein the microprocessor counts the pulse signals and, as consequence, activates the radio transmitter to transmit via the transmitting antenna coded binary signals to the electronic receiving device, wherein the electronic receiving device comprises a remote control receiver coupled to a receiver antenna for receiving the coded binary signals, a microprocessor for decoding and analysing the received coded binary signals, a system for detecting position of the referee within the area of a playing field and connected bidirectionally with the microprocessor, a power pack for powering the electronic receiving device, a relay and a luminous signalling system, wherein the microprocessor decodes and analyses the coded binary signals and, on the basis of the decoding and analysis for checking their consistence with predetermined parameters, including an unique address of the radio transmitter, converts the coded binary signals into an executive signal, which is input to the relay, wherein the output of the relay is connected with the luminous signalling system, which in turn is electrically connected to LEDs mounted in elastic LED strips, wherein the executive signal switches on the luminous signalling system and the LEDs in the LED strips so as to identify the referee at the specific point of the playing field in order to attract attention of players to the referee, wherein both the electronic receiving device and the LED strips are installed on the surface of the playing field such as a pitch, a court or in a swimming pool in locations decisive for determining whether the game is played in accordance with rules of a given sports discipline.
An integrated asymmetric brake system for an aircraft comprising: a housing; a control surface actuator arranged in the housing, the control surface actuator including a torque limiter output member and being operable to selectively deploy and retract a control surface; an asymmetry brake system arranged in the housing and operably connected to the control surface actuator and the torque limiter output member, the asymmetry brake system including an asymmetry gear train, a dual channel electro-mechanical (E/M) brake coupled thereto and a ball ramp brake assembly operatively connected to the asymmetry gear train and the dual channel electro-mechanical brake; a controller configured to control operation of the control surface actuator and to actuate the asymmetric brake system; wherein the asymmetry brake system is configured to prevent deployment of the control surface by activating the torque limiter output member upon detecting an asymmetry event; wherein the integrated brake system further comprises an asymmetry brake test monitor switch mounted in the housing and operably coupled to the asymmetry brake system, wherein the controller is further configured to monitor the asymmetry brake test monitor switch to confirm functionality of the asymmetry brake system prior to flight. a housing; a control surface actuator arranged in the housing, the control surface actuator including a torque limiter output member and being operable to selectively deploy and retract a control surface; an asymmetry brake system arranged in the housing and operably connected to the control surface actuator and the torque limiter output member, the asymmetry brake system including an asymmetry gear train, a dual channel electro-mechanical (E/M) brake coupled thereto and a ball ramp brake assembly operatively connected to the asymmetry gear train and the dual channel electro-mechanical brake; a controller configured to control operation of the control surface actuator and to actuate the asymmetric brake system; wherein the asymmetry brake system is configured to prevent deployment of the control surface by activating the torque limiter output member upon detecting an asymmetry event; wherein the integrated brake system further comprises an asymmetry brake test monitor switch mounted in the housing and operably coupled to the asymmetry brake system, wherein the controller is further configured to monitor the asymmetry brake test monitor switch to confirm functionality of the asymmetry brake system prior to flight.
Two dimensional barcode for placement on a portion of a neck of a bottle, comprising a top edge, a bottom edge, a left edge a right edge, and code elements arranged along horizontal lines extending between the left edge and the right edge, characterized in that the horizontal lines of code elements and the top and bottom edges are curved such that the top edge has a convex shape and the bottom edge a concave shape.
A surgical instrument, comprising: a displacement member configured to translate within the surgical instrument over a plurality of predefined zones; a motor coupled to the displacement member to translate the displacement member; a control circuit coupled to the motor; a position sensor coupled to the control circuit, the position sensor configured to monitor the position of the displacement member; a timer circuit coupled to the control circuit, the timer circuit configured to measure elapsed time; wherein the control circuit is configured to: receive, from the position sensor, a position of the displacement member in a current zone defined by a predetermined displacement interval; measure time as the displacement member moves from a parked position to a target position; wherein an initial zone is defined as the distance traveled by the displacement member from the parked position to the target position; wherein the control circuit is configured to: compare the measured time to a predetermined time stored in a memory coupled to the control circuit and set a command velocity of the displacement member for a first zone subsequent to the initial zone based on the comparison between the measured time and the predetermined time. a displacement member configured to translate within the surgical instrument over a plurality of predefined zones; a motor coupled to the displacement member to translate the displacement member; a control circuit coupled to the motor; a position sensor coupled to the control circuit, the position sensor configured to monitor the position of the displacement member; a timer circuit coupled to the control circuit, the timer circuit configured to measure elapsed time; wherein the control circuit is configured to: receive, from the position sensor, a position of the displacement member in a current zone defined by a predetermined displacement interval; measure time as the displacement member moves from a parked position receive, from the position sensor, a position of the displacement member in a current zone defined by a predetermined displacement interval; measure time as the displacement member moves from a parked position to a target position;
An elevator system, comprising: an elevator car; a counterweight; roping coupling the elevator car and the counterweight, the roping supporting a load of the elevator car and the counterweight; and a plurality of safeties (32, 36), wherein: the plurality of safeties (32, 36) includes a plurality of elevator car safeties supported for movement with the elevator car, the elevator car safeties being selectively actuated to engage a stationary surface to prevent movement of the elevator car, characterized in that the plurality of safeties further includes a plurality of counterweight safeties supported for movement with the counterweight, the counterweight safeties being selectively actuated to engage a stationary surface to prevent movement of the counterweight, and the plurality of safeties (32, 36) are configured for wireless communication causing essentially simultaneous actuation of the elevator car safeties and the counterweight safeties. an elevator car; a counterweight; roping coupling the elevator car and the counterweight, the roping supporting a load of the elevator car and the counterweight; and a plurality of safeties (32, 36), wherein: the plurality of safeties (32, 36) includes a plurality of elevator car safeties supported for movement with the elevator car, the elevator car safeties being selectively actuated to engage a stationary surface to prevent movement of the elevator car, characterized in that the plurality of safeties further includes a plurality of counterweight safeties supported for movement with the counterweight, the counterweight safeties being selectively actuated to engage a stationary surface to prevent movement of the counterweight, and the plurality of safeties (32, 36) are configured for wireless communication causing essentially simultaneous actuation of the elevator car safeties and the counterweight safeties. the plurality of safeties (32, 36) includes a plurality of elevator car safeties supported for movement with the elevator car, the elevator car safeties being selectively actuated to engage a stationary surface to prevent movement of the elevator car, characterized in that the plurality of safeties further includes a plurality of counterweight safeties supported for movement with the counterweight, the counterweight safeties being selectively actuated to engage a stationary surface to prevent movement of the counterweight, and the plurality of safeties (32, 36) are configured for wireless communication causing essentially simultaneous actuation of the elevator car safeties and the counterweight safeties.
An apparatus for improving thermal-mechanical stress resistance in a delayed coking drum having a drum shell, the apparatus comprising: a support skirt section configured to mount to and to assist in supporting the coking drum above a ground surface; a joining edge for joining the support skirt section to an exterior portion of the drum shell; and a T-shaped slot formed in the support skirt section and located proximate the joining edge. a support skirt section configured to mount to and to assist in supporting the coking drum above a ground surface; a joining edge for joining the support skirt section to an exterior portion of the drum shell; and a T-shaped slot formed in the support skirt section and located proximate the joining edge.
A stannate luminescent material, having a general molecular formula of Ln 2-x Eu x Sn 2 O 7 @SnO 2 @M y, wherein Ln is selected from the group consisting of Gd, Y, and La; M is at least one metal nanoparticles selected from the group consisting of Ag, Au, Pt, Pd, and Cu; 0 < x ≤ 1.5; y is a molar ratio between M and the sum of Sn in Ln 2-x Eu x Sn 2 O 7 and in SnO 2 @M y, 0 < y ≤ 1 × 10 − 2; @ represents coating; the stannate luminescent material uses M as a core, SnO 2 as an inner shell, and Ln 2-x Eu x Sn 2 O 7 as an outer shell.
An optical system for a digital micromirror device illuminator, comprising: a light emitting diode array; a tapered non-imaging collection optic having an input aperture in optical communication with the LED array to receive optical energy emitted by the LED array and having an output aperture; characterized by: a reflective aperture stop; and a telecentric lens system (167, 168, 169) disposed between the tapered non-imaging collection optic and the reflective aperture stop along an optical axis defined between the LED array and the reflective aperture stop, the telecentric lens system (167, 168, 169) being telecentric in both object and image space as well as at the aperture stop; and configured as a first half of a symmetric one to one imager for an object plane on the optical axis and as a second half of the symmetric one to one imager for optical energy reflected from the reflective aperture stop toward an image plane on the optical axis to enhance the optical energy passing through the reflective aperture stop. a light emitting diode array; a tapered non-imaging collection optic having an input aperture in optical communication with the LED array to receive optical energy emitted by the LED array and having an output aperture; characterized by: a reflective aperture stop; and a telecentric lens system (167, 168, 169) disposed between the tapered non-imaging collection optic and the reflective aperture stop along an optical axis defined between the LED array and the reflective aperture stop, the telecentric lens system (167, 168, 169) being telecentric in both object and image space as well as at the aperture stop; and configured as a first half of a symmetric one to one imager for an object plane on the optical axis and as a second half of the symmetric one to one imager for optical energy reflected from the reflective aperture stop toward an image plane on the optical axis to enhance the optical energy passing through the reflective aperture stop. a reflective aperture stop; and a telecentric lens system (167, 168, 169) disposed between the tapered non-imaging collection optic and the reflective aperture stop along an optical axis defined between the LED array and the reflective aperture stop, the telecentric lens system (167, 168, 169) being telecentric in both object and image space as well as at the aperture stop; and configured as a first half of a symmetric one to one imager for an object plane on the optical axis and as a second half of the symmetric one to one imager for optical energy reflected from the reflective aperture stop toward an image plane on the optical axis to enhance the optical energy passing through the reflective aperture stop.