Device for the treatment of biological tissue, in particular for plasma treatment of biological tissue, of for example a human organism, such as for example the trabecular meshwork of the human eye, the device comprising a hollow needle-like tubular section with a distal end comprising a distal, central axial aperture, and a light guide guided in the tubular section, wherein the tubular section comprises subsequent to the distal end an inner plasma chamber configured for generating therein a light-induced plasma, wherein the distal end is configured for use in applying a light-induced plasma to the tissue by inserting the needle-like tubular section into the tissue with the distal end ahead such that the distal end is placed at the tissue to be treated with plasma discharged from the plasma chamber through the central, axial aperture, wherein the plasma chamber is communicatively coupled with the distal, central axial aperture in the distal end, and adjoins, within the tubular section, a light injection section for injecting laser light, in particular laser light pulses, supplied by a laser light source to the light injection section, into the plasma chamber for plasma generation, wherein the light injection section includes, as an axial end face facing the plasma chamber, a light exit face of the light guide, and the distal end comprises an inner axial face that is oriented towards the plasma chamber, the light guide arranged adjacent to the plasma chamber such that the light exit surface faces the inner axial face, wherein the inner axial face acts as a laser absorption target for absorbing a part of the laser light emitted from the light injection section, and wherein the light guide is configured and arranged such that at least a portion of the light exiting the light exit surface impinges on the inner axial face to generate within the plasma chamber a plasma in which the volumetric material associated with the inner axial face acts as the light absorption target for plasma formation. a hollow needle-like tubular section with a distal end comprising a distal, central axial aperture, and a light guide guided in the tubular section, wherein the tubular section comprises subsequent to the distal end an inner plasma chamber configured for generating therein a light-induced plasma, wherein the distal end is configured for use in applying a light-induced plasma to the tissue by inserting the needle-like tubular section into the tissue with the distal end ahead such that the distal end is placed at the tissue to be treated with plasma discharged from the plasma chamber through the central, axial aperture, wherein the plasma chamber is communicatively coupled with the distal, central axial aperture in the distal end, and adjoins, within the tubular section, a light injection section for injecting laser light, in particular laser light pulses, supplied by a laser light source to the light injection section, into the plasma chamber for plasma generation, wherein the light injection section includes, as an axial end face facing the plasma chamber, a light exit face of the light guide, and the distal end comprises an inner axial face that is oriented towards the plasma chamber, the light guide arranged adjacent to the plasma chamber such that the light exit surface faces the inner axial face, wherein the inner axial face acts as a laser absorption target for absorbing a part of the laser light emitted from the light injection section, and wherein the light guide is configured and arranged such that at least a portion of the light exiting the light exit surface impinges on the inner axial face to generate within the plasma chamber a plasma in which the volumetric material associated with the inner axial face acts as the light absorption target for plasma formation.