mhurhangee/ep-ind-claims huggingface dataset:
A chemically modified double stranded nucleic acid molecule that: (i) is selected from the sequences within Tables 1-2; or (ii) comprises at least 12 contiguous nucleotides of a sequence selected from the sequences within Tables 1-2, wherein the chemically modified double stranded nucleic acid molecule comprises a guide strand and a passenger strand, wherein the region of the molecule that is double stranded is from 8-15 nucleotides long, wherein the guide strand contains a single stranded region that is 4-12 nucleotides long, wherein the single stranded region of the guide strand contains 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12 phosphorothioate modifications, wherein at least 40% of the nucleotides of the double stranded nucleic acid are modified, wherein at least one of the nucleotides contains a 2' chemical modification selected from 2'OMe or 2'Fluoro, wherein the chemically modified double stranded nucleic acid molecule is linked to one or more hydrophobic conjugates, and wherein one or more of the hydrophobic conjugates is cholesterol. (i) is selected from the sequences within Tables 1-2; or (ii) comprises at least 12 contiguous nucleotides of a sequence selected from the sequences within Tables 1-2, wherein the chemically modified double stranded nucleic acid molecule comprises a guide strand and a passenger strand, wherein the region of the molecule that is double stranded is from 8-15 nucleotides long, wherein the guide strand contains a single stranded region that is 4-12 nucleotides long, wherein the single stranded region of the guide strand contains 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12 phosphorothioate modifications, wherein at least 40% of the nucleotides of the double stranded nucleic acid are modified, wherein at least one of the nucleotides contains a 2' chemical modification selected from 2'OMe or 2'Fluoro, wherein the chemically modified double stranded nucleic acid molecule is linked to one or more hydrophobic conjugates, and wherein one or more of the hydrophobic conjugates is cholesterol. wherein the chemically modified double stranded nucleic acid molecule comprises a guide strand and a passenger strand, wherein the region of the molecule that is double stranded is from 8-15 nucleotides long, wherein the guide strand contains a single stranded region that is 4-12 nucleotides long, wherein the single stranded region of the guide strand contains 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12 phosphorothioate modifications, wherein at least 40% of the nucleotides of the double stranded nucleic acid are modified, wherein at least one of the nucleotides contains a 2' chemical modification selected from 2'OMe or 2'Fluoro, wherein the chemically modified double stranded nucleic acid molecule is linked to one or more hydrophobic conjugates, and wherein one or more of the hydrophobic conjugates is cholesterol.
A test system, comprising: a probe suitable to be coupled between a test measurement device and a device under test, DUT, said probe comprising: a signal input (204a, 404a, 504a) configured to electrically receive an active signal from the DUT; a signal output (204b, 404b, 504b) configured to electrically provide the active signal to the test measurement device; an input ground (206a, 406a, 506a) configured to electrically connect to a ground of the DUT; an output ground (206b, 406b, 506b) configured to electrically connect to a ground of the test measurement device; and a probe ground path electrically coupled between the input ground and the output ground; and a probe ground connection checking device coupled to the probe ground path and configured to automatically determine whether a low impedance ground connection exists between said probe input ground and said DUT ground, wherein said probe ground connection checking device is configured to determine whether the low impedance ground connection exists by using an impedance of an electrical path from said probe input ground through said DUT ground, an auxiliary ground connection from said DUT ground to said test measurement device ground, and back to said probe output ground. a signal input (204a, 404a, 504a) configured to electrically receive an active signal from the DUT; a signal output (204b, 404b, 504b) configured to electrically provide the active signal to the test measurement device; an input ground (206a, 406a, 506a) configured to electrically connect to a ground of the DUT; an output ground (206b, 406b, 506b) configured to electrically connect to a ground of the test measurement device; and a probe ground path electrically coupled between the input ground and the output ground; and a probe ground connection checking device coupled to the probe ground path and configured to automatically determine whether a low impedance ground connection exists between said probe input ground and said DUT ground, wherein said probe ground connection checking device is configured to determine whether the low impedance ground connection exists by using an impedance of an electrical path from said probe input ground through said DUT ground, an auxiliary ground connection from said DUT ground to said test measurement device ground, and back to said probe output ground.
Method for obtaining a heavy load acceleration of hybrid vehicles by means of an internal combustion engine and of an electric machine, characterised in that it consists of ordering the electric machine to provide torque when it is detected that the internal combustion engine has started and has exceeded optimum torque conditions sufficient for providing a torque capable of following a set value of a torque for driving the vehicle and when it is detected that the clutch position is close to the slipping point.
An instrument accessory device (201, 203), comprising: a body having a proximal end, a distal end, a longitudinal axis, and a wall defining an instrument lumen extending between the proximal end and the distal end along the longitudinal axis of the body, the instrument lumen having an inlet and an outlet at the respective proximal end and distal end of the body, the instrument lumen configured to slidingly receive a length of an instrument (270, 280) extendible therethrough; an expandable member disposed about the wall at the distal end of the body, the expandable member extending between a proximal end and a distal end along a longitudinal axis of the expandable member; an elongate delivery member attached to the body and in communication with the expandable member at a distal end of the delivery member, the delivery member configured to slide the instrument lumen of the body and the expandable member along the length of the instrument (270, 280) when extended therethrough; a handle at a proximal end of the elongate delivery member; and a stylet having a cap at a proximal end of the stylet, the cap reversibly coupled to the handle. a body having a proximal end, a distal end, a longitudinal axis, and a wall defining an instrument lumen extending between the proximal end and the distal end along the longitudinal axis of the body, the instrument lumen having an inlet and an outlet at the respective proximal end and distal end of the body, the instrument lumen configured to slidingly receive a length of an instrument (270, 280) extendible therethrough; an expandable member disposed about the wall at the distal end of the body, the expandable member extending between a proximal end and a distal end along a longitudinal axis of the expandable member; an elongate delivery member attached to the body and in communication with the expandable member at a distal end of the delivery member, the delivery member configured to slide the instrument lumen of the body and the expandable member along the length of the instrument (270, 280) when extended therethrough; a handle at a proximal end of the elongate delivery member; and a stylet having a cap at a proximal end of the stylet, the cap reversibly coupled to the handle.
A method of operating a base station in a cellular communications network to provide a power boost for a communications link between the base station and a user device over a communications link channel having a full channel bandwidth including a plurality of sub-carrier frequencies comprising: receiving a wideband channel quality index from the user device; receiving a plurality of sub-band channel quality indicies from the user device; determining whether a power boost is needed for a communications link between the base station and the user device; and if a power boost is needed for the communications link between the base station and the user device, using a subset of the plurality of sub-carrier frequencies of the communications link channel as a reduced bandwidth channel for the communications link to the user device such that signal power is concentrated on the subset of the plurality of sub-carrier frequencies in the reduced bandwidth channel rather than distributed across the full channel bandwidth, thereby providing a power boost for the communications link to the user device; wherein the subset of the plurality of sub-carrier frequencies are determined based at least in part on the received plurality of sub-band channel quality indices; and coordinating the subset of the plurality of sub-carrier frequencies of the communications link channel with at least one other base station, wherein the other base station uses a different subset of the plurality of sub-carrier frequencies, where the subset of the plurality of sub-carrier frequencies are coordinated based on an indication of a number of resource blocks, each resource block containing twelve sub-carrier frequencies. receiving a wideband channel quality index from the user device; receiving a plurality of sub-band channel quality indicies from the user device; determining whether a power boost is needed for a communications link between the base station and the user device; and if a power boost is needed for the communications link between the base station and the user device, using a subset of the plurality of sub-carrier frequencies of the communications link channel as a reduced bandwidth channel for the communications link to the user device such that signal power is concentrated on the subset of the plurality of sub-carrier frequencies in the reduced bandwidth channel rather than distributed across the full channel bandwidth, thereby providing a power boost for the communications link to the user device; wherein the subset of the plurality of sub-carrier frequencies are determined based at least in part on the received plurality of sub-band channel quality indices; and coordinating the subset of the plurality of sub-carrier frequencies of the communications link channel with at least one other base station, wherein the other base station uses a different subset of the plurality of sub-carrier frequencies, where the subset of the plurality of sub-carrier frequencies are coordinated based on an indication of a number of resource blocks, each resource block containing twelve sub-carrier frequencies.
A burner assembly for a combustion chamber of a gas-turbine unit, comprising: a main burner; a pilot burner, arranged inside the main burner and coaxial therewith; and an optical probe, housed inside the pilot burner and coaxial with the main burner and with the pilot burner; wherein the optical probe comprises a tubular body, having an optical window (51; 51') at a first end, and a portion of a waveguide housed inside the tubular body through a second end of the tubular body and extending to the optical window (51; 51'), the waveguide thus optically facing the flame area both of the main burner and the pilot burner; wherein the tubular body comprises an air intake at the second end, the air intake being configured to feed a flow of cooling air inside the tubular body. a main burner; a pilot burner, arranged inside the main burner and coaxial therewith; and an optical probe, housed inside the pilot burner and coaxial with the main burner and with the pilot burner; wherein the optical probe comprises a tubular body, having an optical window (51; 51') at a first end, and a portion of a waveguide housed inside the tubular body through a second end of the tubular body and extending to the optical window (51; 51'), the waveguide thus optically facing the flame area both of the main burner and the pilot burner; wherein the tubular body comprises an air intake at the second end, the air intake being configured to feed a flow of cooling air inside the tubular body.
A method for forming a hole, the method comprising: inserting an endcap into a first end of a guide tube; placing the endcap at a position proximate to a second end of the guide tube, wherein the second end is proximate to a working face comprising a geologic material; loading a projectile into a ram accelerator, wherein: the projectile is configured to produce a ram-effect combustion reaction in one or more combustible gasses within the ram accelerator; and an output of the ram accelerator is coupled to the first end of the guide tube; boosting the projectile to a ram velocity; accelerating the projectile along at least a portion of the ram accelerator by combusting one or more combustible gasses in a ram combustion effect; and prior to exit from the guide tube, penetrating the endcap with the projectile. inserting an endcap into a first end of a guide tube; placing the endcap at a position proximate to a second end of the guide tube, wherein the second end is proximate to a working face comprising a geologic material; loading a projectile into a ram accelerator, wherein: the projectile is configured to produce a ram-effect combustion reaction in one or more combustible gasses within the ram accelerator; and an output of the ram accelerator is coupled to the first end of the guide tube; the projectile is configured to produce a ram-effect combustion reaction in one or more combustible gasses within the ram accelerator; and an output of the ram accelerator is coupled to the first end of the guide tube; boosting the projectile to a ram velocity; accelerating the projectile along at least a portion of the ram accelerator by combusting one or more combustible gasses in a ram combustion effect; and prior to exit from the guide tube, penetrating the endcap with the projectile.
Process for moving and fixing at least two wooden panels or beams (1, 1a, 1b), the process comprising the following steps: a) preparing at least one first wooden panel or a first wooden beam (1,1a,1b), in which a corner of the wooden panel is cut or a cavity is obtained through the removal of material of the beam; b) fixing at least one connecting element comprising gripping means and holes by means of anchoring means against a surface of the wooden panel or beam (1,1a,1b), in which the at least one connecting element is added to the corner cut or arranged in the cavity on the surface of the wooden panel or beam (1,1a,1b), wherein anchoring means are anchored into the wooden panel or beam (1,1a,1b), whose connecting element is positioned on the surface of the wooden panel or beam (1,1a,1b), c) movement of the wooden panel or beam (1, 1a, 1b) coupling it onto at least one connecting element in the holes, d) fixing the wooden panel or beam (1,1a,1b) to a second wooden panel or wooden beam of this type, at least one connecting element and one connecting plate being fixed to a further connecting element arranged on the further wooden panel or second beam (1,1a,1b), and whose connection of the connecting elements forms a node with the connecting plate. a) preparing at least one first wooden panel or a first wooden beam (1,1a,1b), in which a corner of the wooden panel is cut or a cavity is obtained through the removal of material of the beam; b) fixing at least one connecting element comprising gripping means and holes by means of anchoring means against a surface of the wooden panel or beam (1,1a,1b), in which the at least one connecting element is added to the corner cut or arranged in the cavity on the surface of the wooden panel or beam (1,1a,1b), wherein anchoring means are anchored into the wooden panel or beam (1,1a,1b), whose connecting element is positioned on the surface of the wooden panel or beam (1,1a,1b), c) movement of the wooden panel or beam (1, 1a, 1b) coupling it onto at least one connecting element in the holes, d) fixing the wooden panel or beam (1,1a,1b) to a second wooden panel or wooden beam of this type, at least one connecting element and one connecting plate being fixed to a further connecting element arranged on the further wooden panel or second beam (1,1a,1b), and whose connection of the connecting elements forms a node with the connecting plate.
A composite structure having a Shore A hardness according to DIN 53505 of 20 to 45 as a coating for an airbag cover, wherein the composite structure contains a foam layer, a cover layer and a lacquer layer in this order, the foam layer has a density according to ISO 845 of 40 to 100 kg/m 3 and a gel content according to ASTM D2765-16 of 20 to 80 % and comprises a polyolefin and the cover layer has a gel content according to ASTM D2765-16 of 0 to 20 %, is thermoplastic and comprises at least two compact sublayers each comprising at least one thermoplastic polymer selected from polyolefin and polyvinyl chloride.
Processing system having a polar structure for planar substrates, ∘ having a central base module with a vacuum transfer chamber for the substrates, ∘ having process stations which are arranged in a polar manner with respect to the base module and are to be connected circumferentially to the vacuum transfer chamber so as to provide a delimitation with respect to the surroundings of the base module, ∘ having a handling device for the substrates accommodated by the vacuum transfer chamber, ∘ having a central rotary support lying in the central region of the base module, and ∘ having a vacuum transfer chamber which is to be positioned in a sealingly connected manner in connection positions with respect to the process stations, which are spaced apart radially from the rotary support and are grouped around the base module, wherein the vacuum transfer chamber has a passage opening through which the handling device can reach and which can be shutoff via a switchable coupling valve, characterized in that the vacuum transfer chamber is carried eccentrically with respect to the base module via the central rotary support so as to be radially and height-adjustably freely pivotable in space. ∘ having a central base module with a vacuum transfer chamber for the substrates, ∘ having process stations which are arranged in a polar manner with respect to the base module and are to be connected circumferentially to the vacuum transfer chamber so as to provide a delimitation with respect to the surroundings of the base module, ∘ having a handling device for the substrates accommodated by the vacuum transfer chamber, ∘ having a central rotary support lying in the central region of the base module, and ∘ having a vacuum transfer chamber which is to be positioned in a sealingly connected manner in connection positions with respect to the process stations, which are spaced apart radially from the rotary support and are grouped around the base module,
A method comprising: obtaining a first task to print, a second task to print, and a printing mode, wherein the second task is different from and independent of the first task; defining a layout of a printing image comprising a center region configured to contain the first task, and a peripheral region configured to contain the second task; choosing between overlaying, underlaying and stitching the second task and the first task based on the printing mode, wherein overlaying includes printing the second task over the first task in the peripheral region, underlaying includes printing the second task under the first task in the peripheral region, and stitching includes printing the second task around the first task in the peripheral region; determining a number of printing images needed to print the first task; and arranging the first task and the second task within the determined number of printing images. obtaining a first task to print, a second task to print, and a printing mode, wherein the second task is different from and independent of the first task; defining a layout of a printing image comprising a center region configured to contain the first task, and a peripheral region configured to contain the second task; choosing between overlaying, underlaying and stitching the second task and the first task based on the printing mode, wherein overlaying includes printing the second task over the first task in the peripheral region, underlaying includes printing the second task under the first task in the peripheral region, and stitching includes printing the second task around the first task in the peripheral region; determining a number of printing images needed to print the first task; and arranging the first task and the second task within the determined number of printing images.
A method for encoding first high bit depth grayscale images to second images comprising fewer Bits Per Pixel per channel than said first images, said method comprising: dividing losslessly first BPP data of a channel from a first image among two or more channels of a multi-channel image format to define second BPP data of a second image for loading by a display device (128, 160, 172, 174, 176) supporting said format, said first BPP data divided in accordance with a transformation for applying by the display device to display any portion of the first image within the display capability of the display device wherein the transformation to be applied by the display device (128, 160, 172, 174, 176) is a color matrix filter transformation natively supported by the display device also supporting applying a linear window and level operation to the image data and said color matrix filter transformation comprises floating point operations to support greater than 8 bit per pixel images, and at least one of storing the second image or providing the second image for display by the display device (128, 160, 172, 174, 176).
A glaucoma drainage device for implantation in an eye, comprising: a tube having a distal end and a proximal end, the tube defining an internal lumen extending between the distal and proximal ends (31a, 31b) of the tube; and fixation means extending radially outward from the tube and disposed between the distal and proximal ends (31a, 31b) of the tube, the fixation means including a taper and a shoulder, wherein the taper extends from a taper proximal end to a taper distal end along a portion of the length of the tube, wherein the taper has a larger diameter at the taper proximal end than at the taper distal end and the taper is configured to engage and seal ocular tissue of a tissue passageway through which the distal end of the tube is inserted, characterised in that the shoulder has a bearing surface that acts as a transition from the taper and extends abruptly from the taper proximal end and in that the bearing surface of the shoulder is configured to bear against ocular tissue at the proximal end of the tissue passageway to prevent further distal movement of the device into the tissue passageway. a tube having a distal end and a proximal end, the tube defining an internal lumen extending between the distal and proximal ends (31a, 31b) of the tube; and fixation means extending radially outward from the tube and disposed between the distal and proximal ends (31a, 31b) of the tube, the fixation means including a taper and a shoulder, wherein the taper extends from a taper proximal end to a taper distal end along a portion of the length of the tube, wherein the taper has a larger diameter at the taper proximal end than at the taper distal end and the taper is configured to engage and seal ocular tissue of a tissue passageway through which the distal end of the tube is inserted, characterised in that the shoulder has a bearing surface that acts as a transition from the taper and extends abruptly from the taper proximal end and in that the bearing surface of the shoulder is configured to bear against ocular tissue at the proximal end of the tissue passageway to prevent further distal movement of the device into the tissue passageway.