A medical device for capturing at least one corpus located in tubular organ comprising a guidewire extending along a proximal-distal direction and at least one capturing unit; the capturing unit envelops at least a distal portion of the guidewire, having a proximal segment and a distal segment integrally linked to one another by a deformable corpus-engaging segment, and at least one of the proximal or distal segments displaceable along the guidewire towards the other segment to thereby deform the corpus-engaging segment into a deformed state; the corpus-engaging segment comprising a plurality of flexible and deformable elongated elements extending between two ends, integral with both the distal and the proximal segments, each of the elongated elements having an integral, apex-forming portion in between a proximal portion adjacent the proximal segment and a distal portion adjacent the distal segment, a non-deformed state in which the elongated element extends along the guidewire and adjacent thereto, and having a deformed state in which the elongated element arches radially away from the guidewire defining a loop with an apex formed by the apex-forming portion; at least one of said elongated elements comprising one or more integral spikes that in the non-deformed state project from the elongated element in a first direction generally parallel to the guidewire, and that upon deforming the elongated element into the deformed state, switches its orientation such that the spike projects in a second direction different from the first direction, characterized in that said one or more integral spikes (i) comprise at least one distal spike formed at the distal portion, in the non-deformed state the at least one distal spike points in the general direction of the distal segment, and in the deformed state the at least one distal spike points generally in the direction of the proximal segment, and/or (ii) comprise at least one proximal spike formed at the proximal portion, in the non-deformed state the at least one proximal spike points in a general direction of the proximal segment, and in the deformed state the at least one proximal spike points in the general direction of the distal segment. the capturing unit envelops at least a distal portion of the guidewire, having a proximal segment and a distal segment integrally linked to one another by a deformable corpus-engaging segment, and at least one of the proximal or distal segments displaceable along the guidewire towards the other segment to thereby deform the corpus-engaging segment into a deformed state; envelops at least a distal portion of the guidewire, having a proximal segment and a distal segment integrally linked to one another by a deformable corpus-engaging segment, and at least one of the proximal or distal segments displaceable along the guidewire towards the other segment to thereby deform the corpus-engaging segment into a deformed state; the corpus-engaging segment comprising a plurality of flexible and deformable elongated elements extending between two ends, integral with both the distal and the proximal segments, each of the elongated elements having an integral, apex-forming portion in between a proximal portion adjacent the proximal segment and a distal portion adjacent the distal segment, a non-deformed state in which the elongated element extends along the guidewire and adjacent thereto, and having a deformed state in which the elongated element arches radially away from the guidewire defining a loop with an apex formed by the apex-forming portion; an integral, apex-forming portion in between a proximal portion adjacent the proximal segment and a distal portion adjacent the distal segment, a non-deformed state in which the elongated element extends along the guidewire and adjacent thereto, and having a deformed state in which the elongated element arches radially away from the guidewire defining a loop with an apex formed by the apex-forming portion; at least one of said elongated elements comprising one or more integral spikes that in the non-deformed state project from the elongated element in a first direction generally parallel to the guidewire, and that upon deforming the elongated element into the deformed state, switches its orientation such that the spike projects in a second direction different from the first direction, in the non-deformed state project from the elongated element in a first direction generally parallel to the guidewire, and that upon deforming the elongated element into the deformed state, switches its orientation such that the spike projects in a second direction different from the first direction,