A compound of Formula wherein R" is H, C 1-6 aliphatic, C 3-10 aryl, a 3-8 membered saturated or partially unsaturated carbocyclic ring, a 3-7 membered heterocylic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, a 5-6 membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, each of which is optionally substituted; R 1 is absent or R 1 is A or Q-R; R a is absent or R a is OR 3, CF 3, Hal, NO 2; R b is absent or R b is A or COR; R 2 is each Q is independently a linear or branched alkylene, having 1 to 6 carbon atoms wherein 1-5 H atoms may be replaced by a groupe independently selected from OR 3, Hal, N(R 3) 2, and wherein 1 or 2 CH 2 groups may be replaced by a group independently selected from CO, SO, SO 2 and NR 3, or Q denotes a 4-8-membered bivalent heterocyclic ring, which is saturated, unsaturated or aromatic and which contains 1 to 3 heteroatoms independently selected from N, O and S, each A is independently a linear or branched alkyl having 1 to 10 carbon atoms wherein 1 to 7 H atoms may be replaced by a group independently selected from -OR 3, Hal, NHSO 2 A, SO 2 A, SOA, N(R 3) 2, and wherein 1, 2 or 3 non-adjacent -CH 2 - groups may be replaced by a group independently selected from -CO-, NR 3 and/or -O-, each Hal is independently F, Cl, Br or I, each R is independently hydrogen, C 1-6 aliphatic, C 3-10 aryl, a 3-8 membered saturated or partially unsaturated carbocyclic ring, a 3-7 membered heterocylic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or a 5-6 membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; each of which is optionally substituted; each R 3 is H or C 1 -C 6 alkyl wherein 1 H atom may be replaced by a group selected from OH, O-C 1 -C 6 -alkyl, and Hal; and n is 0 or 1; and pharmaceutically acceptable solvates, tautomers, salts, hydrates and stereoisomers thereof, including mixtures thereof in all ratios. R" is H, C 1-6 aliphatic, C 3-10 aryl, a 3-8 membered saturated or partially unsaturated carbocyclic ring, a 3-7 membered heterocylic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, a 5-6 membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, each of which is optionally substituted; R 1 is absent or R 1 is A or Q-R; R a is absent or R a is OR 3, CF 3, Hal, NO 2; R b is absent or R b is A or COR; R 2 is each Q is independently a linear or branched alkylene, having 1 to 6 carbon atoms wherein 1-5 H atoms may be replaced by a groupe independently selected from OR 3, Hal, N(R 3) 2, and wherein 1 or 2 CH 2 groups may be replaced by a group independently selected from CO, SO, SO 2 and NR 3, or Q denotes a 4-8-membered bivalent heterocyclic ring, which is saturated, unsaturated or aromatic and which contains 1 to 3 heteroatoms independently selected from N, O and S, each A is independently a linear or branched alkyl having 1 to 10 carbon atoms wherein 1 to 7 H atoms may be replaced by a group independently selected from -OR 3, Hal, NHSO 2 A, SO 2 A, SOA, N(R 3) 2, and wherein 1, 2 or 3 non-adjacent -CH 2 - groups may be replaced by a group independently selected from -CO-, NR 3 and/or -O-, each Hal is independently F, Cl, Br or I, each R is independently hydrogen, C 1-6 aliphatic, C 3-10 aryl, a 3-8 membered saturated or partially unsaturated carbocyclic ring, a 3-7 membered heterocylic ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or a 5-6 membered monocyclic heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur; each of which is optionally substituted; each R 3 is H or C 1 -C 6 alkyl wherein 1 H atom may be replaced by a group selected from OH, O-C 1 -C 6 -alkyl, and Hal; and n is 0 or 1;