A vascular access device adapter (110, 210, 310, 610) comprising: a substantially cylindrical housing body (112, 212, 312), the housing body (112, 212, 312) having a proximal end, a distal end, an outer housing sidewall and an aperture defining an interior flow channel, a fitting integrally formed to the proximal end of the housing body (112, 212, 312) projecting proximally from the housing body (112, 212, 312), fitting having a concentric lumen defining an interior flow path of the female adapter, an end cap, the end cap having a concentric proximal opening, a distal wall, an inner sidewall and a concentric aperture extending from the proximal opening to the distal wall, the aperture defining an end cap interior; the distal wall having a concentric hole extending therethrough; and characterized by further comprising: a substantially cylindrical self-healing puncturable septum (130, 230, 330) having a proximal portion and a distal portion, the proximal portion having a smaller diameter than the diameter of the cylindrical distal portion; the transition from the proximal portion to the distal portion defining a ridge, wherein the flow channel and the concentric lumen define a greater flow channel, wherein the housing body (112, 212, 312) is disposed within the end cap, the inner sidewall of the end cap and the outer housing sidewall of the housing body (112, 212, 312) creating a fitment, wherein the puncturable septum (130, 230, 330) is disposed within the concentric aperture of the end cap, the ridge abutting the distal end of the housing body (112, 212, 312), creating a seal. a substantially cylindrical housing body (112, 212, 312), the housing body (112, 212, 312) having a proximal end, a distal end, an outer housing sidewall and an aperture defining an interior flow channel, a fitting integrally formed to the proximal end of the housing body (112, 212, 312) projecting proximally from the housing body (112, 212, 312), fitting having a concentric lumen defining an interior flow path of the female adapter, an end cap, the end cap having a concentric proximal opening, a distal wall, an inner sidewall and a concentric aperture extending from the proximal opening to the distal wall, the aperture defining an end cap interior; the distal wall having a concentric hole extending therethrough; and characterized by further comprising: a substantially cylindrical self-healing puncturable septum (130, 230, 330) having a proximal portion and a distal portion, the proximal portion having a smaller diameter than the diameter of the cylindrical distal portion; the transition from the proximal portion to the distal portion defining a ridge, wherein the flow channel and the concentric lumen define a greater flow channel, wherein the housing body (112, 212, 312) is disposed within the end cap, the inner sidewall of the end cap and the outer housing sidewall of the housing body (112, 212, 312) creating a fitment, wherein the puncturable septum (130, 230, 330) is disposed within the concentric aperture of the end cap, the ridge abutting the distal end of the housing body (112, 212, 312), creating a seal. a substantially cylindrical self-healing puncturable septum (130, 230, 330) having a proximal portion and a distal portion, the proximal portion having a smaller diameter than the diameter of the cylindrical distal portion; the transition from the proximal portion to the distal portion defining a ridge, wherein the flow channel and the concentric lumen define a greater flow channel, wherein the housing body (112, 212, 312) is disposed within the end cap, the inner sidewall of the end cap and the outer housing sidewall of the housing body (112, 212, 312) creating a fitment, wherein the puncturable septum (130, 230, 330) is disposed within the concentric aperture of the end cap, the ridge abutting the distal end of the housing body (112, 212, 312), creating a seal.