A device for adjusting a standing insulin regimen for a subject, the standing insulin regimen comprising a basal insulin medicament dosage regimen, wherein the device comprises one or more processors and a memory (192/290), the memory storing instructions that, when executed by the one or more processors, perform a method of: obtaining a first data set, the first data set comprising a plurality of autonomous glucose measurements of the subject and, for each respective autonomous glucose measurement in the plurality of autonomous glucose measurements, a timestamp representing when the respective measurement was made; obtaining a second data set from one or more insulin pens used by the subject to apply the standing insulin regimen, the second data set comprising a plurality of insulin medicament records, each insulin medicament record in the plurality of medicament records comprising: (i) a respective insulin medicament injection event including an amount of insulin medicament injected into the subject using a respective insulin pen in the one or more insulin pens and (ii) a corresponding electronic timestamp that is automatically generated by the respective insulin pen upon occurrence of the respective insulin medicament injection event; identifying a plurality of fasting events using the plurality of autonomous glucose measurements of the subject and the respective timestamps in the first data set; applying a first characterization to each respective fasting event in the plurality of fasting events, wherein the first characterization is one of basal regimen adherent and basal regimen nonadherent, a respective fasting event is deemed basal regimen adherent when the second data set includes one or more medicament records that establish, on a temporal and quantitative basis, adherence with the standing basal insulin medicament dosage regimen during the respective fasting event, and a respective fasting event is deemed basal regimen nonadherent when the second data set fails to include one or more medicament records that establish, on a temporal and quantitative basis, adherence with the standing basal insulin medicament dosage regimen during the respective fasting event; and adjusting amounts of insulin medicament dosage in the basal insulin medicament dosage regimen for the subject based upon glucose measurements in the first data set that are contemporaneous with the fasting events that are deemed basal regimen adherent and by excluding glucose measurements in the first data set that are contemporaneous with fasting events that are deemed basal regimen nonadherent. obtaining a first data set, the first data set comprising a plurality of autonomous glucose measurements of the subject and, for each respective autonomous glucose measurement in the plurality of autonomous glucose measurements, a timestamp representing when the respective measurement was made; obtaining a second data set from one or more insulin pens used by the subject to apply the standing insulin regimen, the second data set comprising a plurality of insulin medicament records, each insulin medicament record in the plurality of medicament records comprising: (i) a respective insulin medicament injection event including an amount of insulin medicament injected into the subject using a respective insulin pen in the one or more insulin pens and (ii) a corresponding electronic timestamp that is automatically generated by the respective insulin pen upon occurrence of the respective insulin medicament injection event; identifying a plurality of fasting events using the plurality of autonomous glucose measurements of the subject and the respective timestamps in the first data set; applying a first characterization to each respective fasting event in the plurality of fasting events, wherein the first characterization is one of basal regimen adherent and basal regimen nonadherent, a respective fasting event is deemed basal regimen adherent when the second data set includes one or more medicament records that establish, on a temporal and quantitative basis, adherence with the standing basal insulin medicament dosage regimen during the respective fasting event, and a respective fasting event is deemed basal regimen nonadherent when the second data set fails to include one or more medicament records that establish, on a temporal and quantitative basis, adherence with the standing basal insulin medicament dosage regimen during the respective fasting event; and the first characterization is one of basal regimen adherent and basal regimen nonadherent, a respective fasting event is deemed basal regimen adherent when the second data set includes one or more medicament records that establish, on a temporal and quantitative basis, adherence with the standing basal insulin medicament dosage regimen during the respective fasting event, and a respective fasting event is deemed basal regimen nonadherent when the second data set fails to include one or more medicament records that establish, on a temporal and quantitative basis, adherence with the standing basal insulin medicament dosage regimen during the respective fasting event; and adjusting amounts of insulin medicament dosage in the basal insulin medicament dosage regimen for the subject based upon glucose measurements in the first data set that are contemporaneous with the fasting events that are deemed basal regimen adherent and by excluding glucose measurements in the first data set that are contemporaneous with fasting events that are deemed basal regimen nonadherent.