A medical processing unit configured to: receive a first set of perfusion imaging data from a perfusion imaging system, receive a user selection of a region of interest, determine, based on the first set of perfusion imaging data, at least one parameter representative of a movement of a contrast through a vessel of a patient, generate a first graphical representation of the first set of perfusion imaging data and the at least one parameter determined based on the first set of perfusion imaging data, output the first graphical representation to a graphical user interface for display, receive a second set of perfusion imaging data from the perfusion imaging system, determine, based on the second set of perfusion imaging data, and for the region of interest, at least one parameter representative of the movement of the contrast through the vessel of the patient, generate a second graphical representation of the second set of perfusion imaging data and the at least one parameter determined based on the second set of perfusion imaging data, output the second graphical representation to the graphical user interface for display, determine, for the region of interest, the difference between the at least one parameter determined based on the second set of perfusion imaging data and the at least one parameter determined based on the first set of perfusion imaging data, and output, from the medical processing unit, the difference to the graphical user interface for display, wherein the first set of perfusion imaging data comprises perfusion imaging data obtained prior to an intravascular procedure and the second set of perfusion imaging data comprises perfusion imaging data obtained after the intravascular procedure, wherein outputting the first graphical representation and the second graphical representation to the graphical user interface for display comprises combining the first graphical representation and the second graphical representation to form a third graphical representation, wherein the third graphical representation comprises a first curve representative of the movement of the contrast through the vessel of the patient as shown in the first graphical representation and a second curve representative of the movement of the contrast through the vessel of the patient as shown in the second graphical representation, both plotted on the same set of axes. receive a first set of perfusion imaging data from a perfusion imaging system, receive a user selection of a region of interest, determine, based on the first set of perfusion imaging data, at least one parameter representative of a movement of a contrast through a vessel of a patient, generate a first graphical representation of the first set of perfusion imaging data and the at least one parameter determined based on the first set of perfusion imaging data, output the first graphical representation to a graphical user interface for display, receive a second set of perfusion imaging data from the perfusion imaging system, determine, based on the second set of perfusion imaging data, and for the region of interest, at least one parameter representative of the movement of the contrast through the vessel of the patient, generate a second graphical representation of the second set of perfusion imaging data and the at least one parameter determined based on the second set of perfusion imaging data, output the second graphical representation to the graphical user interface for display, determine, for the region of interest, the difference between the at least one parameter determined based on the second set of perfusion imaging data and the at least one parameter determined based on the first set of perfusion imaging data, and output, from the medical processing unit, the difference to the graphical user interface for display, wherein the first set of perfusion imaging data comprises perfusion imaging data obtained prior to an intravascular procedure and the second set of perfusion imaging data comprises perfusion imaging data obtained after the intravascular procedure, wherein outputting the first graphical representation and the second graphical representation to the graphical user interface for display comprises combining the first graphical representation and the second graphical representation to form a third graphical representation, wherein the third graphical representation comprises a first curve representative of the movement of the contrast through the vessel of the patient as shown in the first graphical representation and a second curve representative of the movement of the contrast through the vessel of the patient as shown in the second graphical representation, both plotted on the same set of axes.