A compound of Formula wherein: X 1 is N or C; X 2 is N or C; R 1 is H, C 1-3 alkyl, or -CH 2 -R 1a, wherein R 1a is phenyl or pyridyl; R6 is H or C 1-3 alkyl; R 7 is: (a.) a group of the formula -C N(R 7a)(R 7b), wherein R 7a and R 7b are independently H or C 1-3 alkyl; or alternatively, R 7a and R 7b together with the N to which they are attached form a 5- to 6-membered heterocyclyl optionally containing 1 additional heteroatom selected from N or O; (b.) Cy,wherein Cy is phenyl or a 5- or 6-membered heteroaryl containing 1 to 3 N ring atoms; wherein Cy is unsubstituted or substituted by 1 to 2 R c substituents selected from: (i.) C 1-4 alkyl, (ii.) a group of the formula -C(R 7d) 2 CO 2 H, wherein R7d is H or C 1-3 alkyl; (iii.) -CH 2 CH 2 OCH 3; or (iv.) tetrahydropyranyl; or alternatively, two R c substituents, together with the atoms to which they are attached form a 5- to 6-membered heterocyclyl containing 1 N ring atom; (c.) -C OH; (d.) H; (e.) C 1-3 alkyl; or (f.) C 1-3 fluoroalkyl; R8 is H, C 1-3 alkyl or C 1-3 hydroxyalkyl; R 9 is: (a.) a group of the formula (b.) a group of the formula or (c.) a group of the formula ring C H is phenyl, thienyl or tetrahydrobenzothienyl; ring C A is phenyl or a 5- to 6-membered heteroaryl containing 1 to 3 heteroatoms selected from N, O, or S; R9a and R9b are each independently H, C 1-6 alkyl, C 1-6 fluoroalkyl, or halo; and the subscript n is 0 or 1; or a pharmaceutically acceptable salt thereof. X 1 is N or C; X 2 is N or C; R 1 is H, C 1-3 alkyl, or -CH 2 -R 1a, wherein R 1a is phenyl or pyridyl; R6 is H or C 1-3 alkyl; R 7 is: (a.) a group of the formula -C N(R 7a)(R 7b), wherein R 7a and R 7b are independently H or C 1-3 alkyl; or alternatively, R 7a and R 7b together with the N to which they are attached form a 5- to 6-membered heterocyclyl optionally containing 1 additional heteroatom selected from N or O; (b.) Cy,wherein Cy is phenyl or a 5- or 6-membered heteroaryl containing 1 to 3 N ring atoms; wherein Cy is unsubstituted or substituted by 1 to 2 R c substituents selected from: (i.) C 1-4 alkyl, (ii.) a group of the formula -C(R 7d) 2 CO 2 H, wherein R7d is H or C 1-3 alkyl; (iii.) -CH 2 CH 2 OCH 3; or (iv.) tetrahydropyranyl; or alternatively, two R c substituents, together with the atoms to which they are attached form a 5- to 6-membered heterocyclyl containing 1 N ring atom; (c.) -C OH; (d.) H; (e.) C 1-3 alkyl; or (f.) C 1-3 fluoroalkyl; (a.) a group of the formula -C N(R 7a)(R 7b), wherein R 7a and R 7b are independently H or C 1-3 alkyl; or alternatively, R 7a and R 7b together with the N to which they are attached form a 5- to 6-membered heterocyclyl optionally containing 1 additional heteroatom selected from N or O; (b.) Cy,wherein Cy is phenyl or a 5- or 6-membered heteroaryl containing 1 to 3 N ring atoms; wherein Cy is unsubstituted or substituted by 1 to 2 R c substituents selected from: (i.) C 1-4 alkyl, (ii.) a group of the formula -C(R 7d) 2 CO 2 H, wherein R7d is H or C 1-3 alkyl; (iii.) -CH 2 CH 2 OCH 3; or (iv.) tetrahydropyranyl; or alternatively, two R c substituents, together with the atoms to which they are attached form a 5- to 6-membered heterocyclyl containing 1 N ring atom; (i.) C 1-4 alkyl, (ii.) a group of the formula -C(R 7d) 2 CO 2 H, wherein R7d is H or C 1-3 alkyl; (iii.) -CH 2 CH 2 OCH 3; or (iv.) tetrahydropyranyl; (c.) -C OH; (d.) H; (e.) C 1-3 alkyl; or (f.) C 1-3 fluoroalkyl; R8 is H, C 1-3 alkyl or C 1-3 hydroxyalkyl; R 9 is: (a.) a group of the formula (b.) a group of the formula or (c.) a group of the formula ring C H is phenyl, thienyl or tetrahydrobenzothienyl; (a.) a group of the formula (b.) a group of the formula or (c.) a group of the formula ring C H is phenyl, thienyl or tetrahydrobenzothienyl; ring C A is phenyl or a 5- to 6-membered heteroaryl containing 1 to 3 heteroatoms selected from N, O, or S; R9a and R9b are each independently H, C 1-6 alkyl, C 1-6 fluoroalkyl, or halo; and the subscript n is 0 or 1; or