An imaging mass spectrometer capable of executing mass analysis to a plurality of measurement points set within a two-dimensional area on a sample by irradiating the measurement points with an ionization probe, the imaging mass spectrometer comprising: a) a region of interest setting unit configured to set a region of interest on a sample and a plurality of measurement points positioned discretely within the region of interest; b) a measurement area setting unit configured to set one or more measurement areas to a respective position set by displacement from a position of the region of interest that partially overlap with the region of interest, and a plurality of different measurement points positioned discretely within each of the measurement areas and positioned so as not to overlap with the plurality of measurement points within the region of interest and a plurality of different measurement points within other measurement areas, wherein the plurality of said different measurement points within a said measurement area are set by displacing the plurality of measurement points within the region of interest such that a position of each one of the plurality of said different measurement points in the measurement area corresponds to said displacement applied to a position of a respective one of each of the plurality of measurement points in the region of interest; c) a measurement method setting unit configured to set, to each of the region of interest and the one or more measurement areas, or to each of the plurality of measurement areas, a measurement method including an analysis condition for executing mass analysis; and d) an analysis execution unit configured to execute mass analysis to the plurality of measurement points included in the region of interest and to the plurality of said different measurement points included in the one or more measurement areas, or to each of said different plurality of measurement points included in the plurality of measurement areas, the mass analysis being executed according to the measurement method set to each of the region of interest and the measurement areas by the measurement method setting unit. a) a region of interest setting unit configured to set a region of interest on a sample and a plurality of measurement points positioned discretely within the region of interest; b) a measurement area setting unit configured to set one or more measurement areas to a respective position set by displacement from a position of the region of interest that partially overlap with the region of interest, and a plurality of different measurement points positioned discretely within each of the measurement areas and positioned so as not to overlap with the plurality of measurement points within the region of interest and a plurality of different measurement points within other measurement areas, wherein the plurality of said different measurement points within a said measurement area are set by displacing the plurality of measurement points within the region of interest such that a position of each one of the plurality of said different measurement points in the measurement area corresponds to said displacement applied to a position of a respective one of each of the plurality of measurement points in the region of interest; c) a measurement method setting unit configured to set, to each of the region of interest and the one or more measurement areas, or to each of the plurality of measurement areas, a measurement method including an analysis condition for executing mass analysis; and d) an analysis execution unit configured to execute mass analysis to the plurality of measurement points included in the region of interest and to the plurality of said different measurement points included in the one or more measurement areas, or to each of said different plurality of measurement points included in the plurality of measurement areas, the mass analysis being executed according to the measurement method set to each of the region of interest and the measurement areas by the measurement method setting unit.