A cannabinoid-loaded formulation, the formulation comprising at least one oil at an amount of between 0.5 and 20 wt % (±10% deviation from the nominal value), at least one hydrophilic surfactant, at least one co-surfactant, and at least 0.1 wt% of at least one cannabinoid, the formulation being in a water-free microemulsion form having a droplet size of between 5 nm and 100 nm (±10% deviation from the nominal value), and said at least one cannabinoid being selected from cannabigerolic acid (CBGA), cannabigerolic acid monomethylether (CBGAM), cannabigerol, cannabigerol monomethylether (CBGM), cannabigerovarinic acid (CBGVA), cannabigerovarin (CBGV), cannabichromenic acid (CBCA), cannabichromene, cannabichromevarinic acid (CBCVA), cannabichromevarin (CBCV), cannabidiolic acid (CBDA), cannabidiol, cannabidiol monomethylether (CBDM), cannabidiol-C 4 (CBD-C 4), cannabidivarinic acid (CBDVA), cannabidiorcol (CBD-C 1), delta-9-tetrahydrocannabinolic acid A (THCA-A), delta-9-tetrahydrocannabinolic acid B (THCA-B), delta-9-tetrahydrocannabinol, delta-9-tetrahydrocannabinolic acid-C 4 (THCA-C 4), delta-9-tetrahydrocannabinol-C 4 (THCA-C 4), delta-9-tetrahydrocannabivarinic acid (THCVA), delta-9-tetrahydrocannabivarin (THCV), delta-9-tetrahydrocannabiorcolic acid (THCA-C 1), delta-9-tetrahydrocannabiorcol (THC-C 1), delta-7-cis-iso-tetrahydrocannabivarin, delta-8-tetrahydrocannabinolic acid A (Δ 8 -THCA), delta-8-tetrahydrocannabinol (Δ 8 -THC), cannabicyclolic acid (CBLA), cannabicyclol, cannabicyclovarin (CBLV), cannabielsoic acid A (CBEA-A), cannabielsoic acid B (CBEA-B), cannabielsoin, cannabinolic acid (CBNA), cannabinol, cannabinol methylether (CBNM), cannabinol-C 4 (CBN-C 4), cannabivarin, cannabinol-C 2 (CBN-C 2), cannabiorcol (CBN-C 1), cannabinodiol (CBND), cannabinodivarin (CBVD), cannabitriol, 10-ethoxy-9-hydroxy-delta-6a-tetrahydrocannabinol, 8,9-dihydroxy-delta-6a-tetrahydrocannabinol, cannabitriolvarin (CBTV), ethoxy-cannabitriolvarin (CBTVE), dehydrocannabifuran (DCBF), cannabifuran, cannabichromanon (CBCN), cannabicitran, 10-oxo-delta-6a-tetrahydrocannabinol (OTHC), delta-9-cis-tetrahydrocannabinol (cis-THC), 3,4,5,6-tetrahydro-7-hydroxy-α-α-2-trimethyl-9-n-propyl-2,6-methano-2H-1-benzoxocin-5-methanol (OH-iso-HHCV), cannabiripsol, trihydroxy-delta-9-tetrahydroxycannabinol (triOH-THC). the formulation being in a water-free microemulsion form having a droplet size of between 5 nm and 100 nm (±10% deviation from the nominal value), and said at least one cannabinoid being selected from cannabigerolic acid (CBGA), cannabigerolic acid monomethylether (CBGAM), cannabigerol, cannabigerol monomethylether (CBGM), cannabigerovarinic acid (CBGVA), cannabigerovarin (CBGV), cannabichromenic acid (CBCA), cannabichromene, cannabichromevarinic acid (CBCVA), cannabichromevarin (CBCV), cannabidiolic acid (CBDA), cannabidiol, cannabidiol monomethylether (CBDM), cannabidiol-C 4 (CBD-C 4), cannabidivarinic acid (CBDVA), cannabidiorcol (CBD-C 1), delta-9-tetrahydrocannabinolic acid A (THCA-A), delta-9-tetrahydrocannabinolic acid B (THCA-B), delta-9-tetrahydrocannabinol, delta-9-tetrahydrocannabinolic acid-C 4 (THCA-C 4), delta-9-tetrahydrocannabinol-C 4 (THCA-C 4), delta-9-tetrahydrocannabivarinic acid (THCVA), delta-9-tetrahydrocannabivarin (THCV), delta-9-tetrahydrocannabiorcolic acid (THCA-C 1), delta-9-tetrahydrocannabiorcol (THC-C 1), delta-7-cis-iso-tetrahydrocannabivarin, delta-8-tetrahydrocannabinolic acid A (Δ 8 -THCA), delta-8-tetrahydrocannabinol (Δ 8 -THC), cannabicyclolic acid (CBLA), cannabicyclol, cannabicyclovarin (CBLV), cannabielsoic acid A (CBEA-A), cannabielsoic acid B (CBEA-B), cannabielsoin, cannabinolic acid (CBNA), cannabinol, cannabinol methylether (CBNM), cannabinol-C 4 (CBN-C 4), cannabivarin, cannabinol-C 2 (CBN-C 2), cannabiorcol (CBN-C 1), cannabinodiol (CBND), cannabinodivarin (CBVD), cannabitriol, 10-ethoxy-9-hydroxy-delta-6a-tetrahydrocannabinol, 8,9-dihydroxy-delta-6a-tetrahydrocannabinol, cannabitriolvarin (CBTV), ethoxy-cannabitriolvarin (CBTVE), dehydrocannabifuran (DCBF), cannabifuran, cannabichromanon (CBCN), cannabicitran, 10-oxo-delta-6a-tetrahydrocannabinol (OTHC), delta-9-cis-tetrahydrocannabinol (cis-THC), 3,4,5,6-tetrahydro-7-hydroxy-α-α-2-trimethyl-9-n-propyl-2,6-methano-2H-1-benzoxocin-5-methanol (OH-iso-HHCV), cannabiripsol, trihydroxy-delta-9-tetrahydroxycannabinol (triOH-THC).