An injection device including - a product container having an injection needle, - a needle protection cap which is releasably fixed to the product container and encloses the injection needle and seals it off in relation to the environment in sterile fashion, - a cap connected by way of a removal element which has an engagement element to the needle protection cap in such a way that the removal of the cap from the injection device causes removal of the needle protection cap from the product container, - wherein the engagement element is in an engagement position in relation to the needle protection cap, wherein in the engagement position a portion of the needle protection cap is arranged distally in alignment with the engagement element, wherein - the cap and the engagement element are so coupled that the cap is moveable or moved relative to the engagement element during removal from the injection device, characterised in that - the injection device has a blocking portion, wherein the blocking portion is so coupled to the cap that the blocking portion is moveable out of a release position into a blocking position and is in the release position when the cap is completely mounted to or fixed to a receiving housing, and that removal of the cap from the receiving housing moves the blocking portion from a release position into a blocking position, wherein the blocking position is of such a configuration that the mobility of the engagement element transversely outwardly is not blocked when the blocking portion is in its release position and wherein the blocking portion is of such a configuration that the mobility of the engagement element is blocked transversely outwardly when the blocking portion is in its blocking position. - a product container having an injection needle, - a needle protection cap which is releasably fixed to the product container and encloses the injection needle and seals it off in relation to the environment in sterile fashion, - a cap connected by way of a removal element which has an engagement element to the needle protection cap in such a way that the removal of the cap from the injection device causes removal of the needle protection cap from the product container, - wherein the engagement element is in an engagement position in relation to the needle protection cap, wherein in the engagement position a portion of the needle protection cap is arranged distally in alignment with the engagement element, wherein - the cap and the engagement element are so coupled that the cap is moveable or moved relative to the engagement element during removal from the injection device, characterised in that - the injection device has a blocking portion, wherein the blocking portion is so coupled to the cap that the blocking portion is moveable out of a release position into a blocking position and is in the release position when the cap is completely mounted to or fixed to a receiving housing, and that removal of the cap from the receiving housing moves the blocking portion from a release position into a blocking position, wherein the blocking position is of such a configuration that the mobility of the engagement element transversely outwardly is not blocked when the blocking portion is in its release position and wherein the blocking portion is of such a configuration that the mobility of the engagement element is blocked transversely outwardly when the blocking portion is in its blocking position.