A compound according to Formula I Meta or para or a pharmaceutically acceptable salt thereof wherein: - A 11 - A 14 are N or CR 11, CR 12, CR 13, CR 14, respectively, with the proviso that no more than two of the four positions A in A 11 -A 14 can be simultaneously N; - A 6, A 7, A 8, A 9, A 10 are N or CR 6, CR 7, CR 8, CR 9, CR 10, respectively, with the proviso that at least one but no more than two of the five positions A in A 6, A 7, A 8, A 9, A 10 is N; - R 1 is C alkyl, C cycloalkyl, C cycloalkylC alkyl, (di)C cycloalkylamino or (di)(C cycloalkylC alkyl)amino, with all carbon atoms of alkyl groups optionally substituted with one or more F and all carbon atoms of cycloalkyl groups optionally substituted with one or more F or methyl; - R 2 and R 3 are independently H, F, methyl, ethyl, hydroxy, methoxy or R 2 and R 3 together is carbonyl, all alkyl groups, if present, optionally being substituted with one or more F; - R 4 is H or C alkyl; - R 5 is H, hydroxyethyl, methoxyethyl, C alkyl, C aryl, C arylC alkyl, C heteroaryl, C heteroarylC alkyl, C cycloalkyl, C cycloalkylC alkyl, C heterocycloalkyl or C heterocycloalkylC alkyl, all groups optionally substituted with one or more F, C alkoxy or cyano; - the sulfonyl group with R 1 is represented by one of R 7, R 8 or R 9; - the remaining R 6 -R 14 are independently H, halogen, amino, C alkoxy, (di)C alkylamino or C alkyl, all of the alkyl groups optionally being substituted with one or more F; and - R 15 is H, C alkyl, C cycloalkyl, C cycloalkylC alkyl, C aryl, C arylC alkyl, C heteroaryl, C heteroarylC alkyl, C heterocycloalkyl or C heterocycloalkyl-C alkyl, all groups optionally substituted with one or more F, C alkoxy or cyano; - and R 16 is C alkyl, C cycloalkyl, C cycloalkylC alkyl, C aryl, C arylC alkyl, C heteroaryl, C heteroarylC alkyl, C heterocycloalkyl or C heterocycloalkyl-C alkyl, all groups optionally substituted with one or more F, C alkyl, C alkoxy or cyano. - A 11 - A 14 are N or CR 11, CR 12, CR 13, CR 14, respectively, with the proviso that no more than two of the four positions A in A 11 -A 14 can be simultaneously N; - A 6, A 7, A 8, A 9, A 10 are N or CR 6, CR 7, CR 8, CR 9, CR 10, respectively, with the proviso that at least one but no more than two of the five positions A in A 6, A 7, A 8, A 9, A 10 is N; - R 1 is C alkyl, C cycloalkyl, C cycloalkylC alkyl, (di)C cycloalkylamino or (di)(C cycloalkylC alkyl)amino, with all carbon atoms of alkyl groups optionally substituted with one or more F and all carbon atoms of cycloalkyl groups optionally substituted with one or more F or methyl; - R 2 and R 3 are independently H, F, methyl, ethyl, hydroxy, methoxy or R 2 and R 3 together is carbonyl, all alkyl groups, if present, optionally being substituted with one or more F; - R 4 is H or C alkyl; - R 5 is H, hydroxyethyl, methoxyethyl, C alkyl, C aryl, C arylC alkyl, C heteroaryl, C heteroarylC alkyl, C cycloalkyl, C cycloalkylC alkyl, C heterocycloalkyl or C heterocycloalkylC alkyl, all groups optionally substituted with one or more F, C alkoxy or cyano; - the sulfonyl group with R 1 is represented by one of R 7, R 8 or R 9; - the remaining R 6 -R 14 are independently H, halogen, amino, C alkoxy, (di)C alkylamino or C alkyl, all of the alkyl groups optionally being substituted with one or more F; and - R 15 is H, C alkyl, C cycloalkyl, C cycloalkylC alkyl, C aryl, C arylC alkyl, C heteroaryl, C heteroarylC alkyl, C heterocycloalkyl or C heterocycloalkyl-C alkyl, all groups optionally substituted with one or more F, C alkoxy or cyano; - and R 16 is C alkyl, C cycloalkyl, C cycloalkylC alkyl, C aryl, C arylC alkyl, C heteroaryl, C heteroarylC alkyl, C heterocycloalkyl or C heterocycloalkyl-C alkyl, all groups optionally substituted with one or more F, C alkyl, C alkoxy or cyano.