mhurhangee/ep-ind-claims huggingface dataset:
A split-and-mix method for synthesising a library of different bifunctional complexes comprising a molecule and an identifier oligonucleotide, said method comprising the steps of i) dispensing in a first synthesis round a display oligonucleotide or a nascent bifunctional complex in separate compartments, ii) exposing each of said compartments to a different reactant, iii) reacting in each compartment said different reactant with at least one reactive group of a chemical reaction site on the display oligonucleotide or the nascent bifunctional complex, iv) adding in each compartment, by enzymatic or chemical ligation, an oligonucleotide tag identifying said reactant to a display oligonucleotide or a nascent bifunctional complex, wherein the substrate for the ligase is in a double stranded form, wherein the substrate comprises a plurality of tags and at least one or more anti-tags, wherein tags and anti-tag(s) is/are at least partly hybridised to each other, wherein tags are covalently linked as a result of the action of an enzyme comprising a ligase activity on the double stranded substrate, but no anti-tags are covalently linked as a result of said ligase action, v) mixing said nascent bifunctional complexes obtained in step iv), vi) dispensing said mixed nascent bifunctional complexes obtained in step v) in separate compartments, vii) repeating steps iii) and iv) for each separate compartment in a second synthesis round, viii) removing said at least one or more anti-tags, and ix) extending at least one primer and complementing a single stranded identifier oligonucleotide comprising a plurality of covalently linked oligonucleotide tags linked to the molecule. i) dispensing in a first synthesis round a display oligonucleotide or a nascent bifunctional complex in separate compartments, ii) exposing each of said compartments to a different reactant, iii) reacting in each compartment said different reactant with at least one reactive group of a chemical reaction site on the display oligonucleotide or the nascent bifunctional complex, iv) adding in each compartment, by enzymatic or chemical ligation, an oligonucleotide tag identifying said reactant to a display oligonucleotide or a nascent bifunctional complex, wherein the substrate for the ligase is in a double stranded form, wherein the substrate comprises a plurality of tags and at least one or more anti-tags, wherein tags and anti-tag(s) is/are at least partly hybridised to each other, wherein tags are covalently linked as a result of the action of an enzyme comprising a ligase activity on the double stranded substrate, but no anti-tags are covalently linked as a result of said ligase action, v) mixing said nascent bifunctional complexes obtained in step iv), vi) dispensing said mixed nascent bifunctional complexes obtained in step v) in separate compartments, vii) repeating steps iii) and iv) for each separate compartment in a second synthesis round, viii) removing said at least one or more anti-tags, and ix) extending at least one primer and complementing a single stranded identifier oligonucleotide comprising a plurality of covalently linked oligonucleotide tags linked to the molecule.
A method for reducing shrinkage variability of aluminum titanate honeycombs comprising preparing an aluminum titanate-forming batch material comprising inorganic batch components comprising at least one alkaline earth carbonate having a particle size distribution; wherein the particle size distribution of the at least one alkaline earth carbonate is selected based on the predicted shrinkage during sintering of the aluminum titanate honeycombs, wherein the at least one alkaline earth carbonate has a first particle size distribution with a median particle size (pd 50) in the range of 0.2 to 2 microns and the at least one alkaline earth carbonate has a second particle size distribution with a median particle size (pd 50) in the range of 15 to 30 microns, wherein: if the predicted shrinkage is above a predetermined value, the particle size distribution of the at least one alkaline earth carbonate is selected such that a weight ratio of particles falling within the first particle size distribution to particles falling within the second particle size distribution is less than if the predicted shrinkage is at or below the predetermined value; or if the predicted shrinkage is below a predetermined value, the particle size distribution of the at least one alkaline earth carbonate is selected such that a weight ratio of particles falling within the first particle size distribution to particles falling within the second particle size distribution is greater than if the predicted shrinkage is at or above the predetermined value; wherein the at least one alkaline earth carbonate having the first and second particle size distributions is strontium carbonate, calcium carbonate or magnesium carbonate. if the predicted shrinkage is above a predetermined value, the particle size distribution of the at least one alkaline earth carbonate is selected such that a weight ratio of particles falling within the first particle size distribution to particles falling within the second particle size distribution is less than if the predicted shrinkage is at or below the predetermined value; or if the predicted shrinkage is below a predetermined value, the particle size distribution of the at least one alkaline earth carbonate is selected such that a weight ratio of particles falling within the first particle size distribution to particles falling within the second particle size distribution is greater than if the predicted shrinkage is at or above the predetermined value;
A computer-implemented method for determining when a traffic signal associated with one or more paths through a road intersection is malfunctioning, the method comprising: receiving a plurality of probe reports from a plurality of devices; identifying whether there is congestion prior to (A310, A330) and subsequent to the road intersection for the one or more paths by analysis of the plurality of probe reports; and determining a traffic signal malfunction based on whether or not congestion is identified prior to and subsequent to the road intersection, wherein, either: (i) a traffic signal malfunction is determined when there is congestion prior to the road intersection for all paths of the one or more paths and no congestion subsequent to the road intersection for all paths of the one or more paths; or (ii) a number of crossing cycles for the road intersection within a time period is calculated and the traffic signal malfunction is determined when the number of crossing cycles equals a threshold crossing cycle count and there is identified congestion prior to the road intersection for all but one path of the one or more paths and there is no identified congestion subsequent to the road intersection for all paths of the one or more paths. receiving a plurality of probe reports from a plurality of devices; identifying whether there is congestion prior to (A310, A330) and subsequent to the road intersection for the one or more paths by analysis of the plurality of probe reports; and determining a traffic signal malfunction based on whether or not congestion is identified prior to and subsequent to the road intersection, wherein, either: (i) a traffic signal malfunction is determined when there is congestion prior to the road intersection for all paths of the one or more paths and no congestion subsequent to the road intersection for all paths of the one or more paths; or (ii) a number of crossing cycles for the road intersection within a time period is calculated and the traffic signal malfunction is determined when the number of crossing cycles equals a threshold crossing cycle count and there is identified congestion prior to the road intersection for all but one path of the one or more paths and there is no identified congestion subsequent to the road intersection for all paths of the one or more paths. (i) a traffic signal malfunction is determined when there is congestion prior to the road intersection for all paths of the one or more paths and no congestion subsequent to the road intersection for all paths of the one or more paths; or (ii) a number of crossing cycles for the road intersection within a time period is calculated and the traffic signal malfunction is determined when the number of crossing cycles equals a threshold crossing cycle count and there is identified congestion prior to the road intersection for all but one path of the one or more paths and there is no identified congestion subsequent to the road intersection for all paths of the one or more paths.
A multi-layer curable composition comprising: a first curable composition layer applied over at least a portion of a substrate; and a second curable composition layer applied over at least a portion of the first curable composition layer; wherein the first curable composition layer and the second curable composition layer both independently comprise a polymeric resin; and wherein the first curable composition layer and/or the second curable composition layer, when cured, comprise a polymerization reaction product of a 1,1 -di-activated vinyl compound, or a multifunctional form thereof, or a combination thereof, wherein: (i) the first curable composition layer comprises an activator compound that activated polymerization reactions in the second curable composition layer when the second curable composition layer was applied over the first coating layer; or (ii) the second curable composition layer comprises an activator compound that activates polymerization reactions in the first curable composition layer upon application of the second curable composition layer over the first curable composition layer, wherein the activator compound comprises a tertiary amine compound or an ionic liquid. a first curable composition layer applied over at least a portion of a substrate; and a second curable composition layer applied over at least a portion of the first curable composition layer; wherein the first curable composition layer and the second curable composition layer both independently comprise a polymeric resin; and wherein the first curable composition layer and/or the second curable composition layer, when cured, comprise a polymerization reaction product of a 1,1 -di-activated vinyl compound, or a multifunctional form thereof, or a combination thereof, wherein: (i) the first curable composition layer comprises an activator compound that activated polymerization reactions in the second curable composition layer when the second curable composition layer was applied over the first coating layer; or (ii) the second curable composition layer comprises an activator compound that activates polymerization reactions in the first curable composition layer upon application of the second curable composition layer over the first curable composition layer, (i) the first curable composition layer comprises an activator compound that activated polymerization reactions in the second curable composition layer when the second curable composition layer was applied over the first coating layer; or (ii) the second curable composition layer comprises an activator compound that activates polymerization reactions in the first curable composition layer upon application of the second curable composition layer over the first curable composition layer, wherein the activator compound comprises a tertiary amine compound or an ionic liquid.
A striker plate for a drive bar fitting of a window or of a door, comprising a base body and a holding part couplable to the base body, wherein the holding part has at least one reception opening for receiving a latching element of a leaf of the window or of the door; and wherein at least one toothed arrangement is provided at the base body and at least one mating toothed arrangement meshing therewith is provided at the holding part, said toothed arrangement and mating toothed arrangement being arranged and aligned such that the toothed arrangement and the mating toothed arrangement enable a fixing of the holding part to the base body selectively at a different spacing between the base body and the holding part, characterized in that the toothed arrangement of the base body forms a latching toothed arrangement and the mating toothed arrangement of the holding part forms a mating latching toothed arrangement such that the holding part is fixed to the base body by a latching engagement, with, starting from the largest possible spacing between the base body and the holding part, the holding part being able to be displaced in the direction of the base body, while temporarily overcoming the latching engagement, by exertion of a force onto the holding part in the direction of the base body in order to selectively reduce the spacing between the base body and the holding part.
A method for monitoring the operation of a component, comprising the steps of: receiving a stream of data samples, wherein each data sample represents a value of a physical parameter of the component; identifying local extrema of said stream of data samples, storing information relating to each local extremum in a respective position of a fixed size buffer; and upon the presence of a cycle formed between two matching endpoints represented by two local maxima or two local minima: i) deleting at least one of the local extrema corresponding to the endpoints of the cycle from the buffer; and ii) storing information related to said cycle in a memory such that the information stored in the memory represents the operation of the component; characterized in that when the buffer is full such that each position of the buffer contains information relating to a unique local extrema, the method further comprises the steps of: i) deleting the information relating to the oldest local extrema from the buffer; ii) calculating a pseudo cycle formed between two endpoints of which one endpoint is represented by the deleted oldest local extrema; and iii) storing information related to the calculated pseudo cycle in the memory. receiving a stream of data samples, wherein each data sample represents a value of a physical parameter of the component; identifying local extrema of said stream of data samples, storing information relating to each local extremum in a respective position of a fixed size buffer; and upon the presence of a cycle formed between two matching endpoints represented by two local maxima or two local minima: i) deleting at least one of the local extrema corresponding to the endpoints of the cycle from the buffer; and ii) storing information related to said cycle in a memory such that the information stored in the memory represents the operation of the component; i) deleting at least one of the local extrema corresponding to the endpoints of the cycle from the buffer; and ii) storing information related to said cycle in a memory such that the information stored in the memory represents the operation of the component; characterized in that when the buffer is full such that each position of the buffer contains information relating to a unique local extrema, the method further comprises the steps of: i) deleting the information relating to the oldest local extrema from the buffer; ii) calculating a pseudo cycle formed between two endpoints of which one endpoint is represented by the deleted oldest local extrema; and iii) storing information related to the calculated pseudo cycle in the memory. i) deleting the information relating to the oldest local extrema from the buffer; ii) calculating a pseudo cycle formed between two endpoints of which one endpoint is represented by the deleted oldest local extrema; and iii) storing information related to the calculated pseudo cycle in the memory.
A controllable polymer actuator comprising: - a dielectric elastomeric film, - a first deformable electrode on a first side of the dielectric elastomeric film, and - a second deformable electrode on a second side of the dielectric elastomeric film, at least partly opposite the first deformable electrode, wherein the first and second deformable electrodes are arranged such that application of a voltage between the first and second deformable electrodes causes an active portion of the controllable polymer actuator to change topography, wherein the controllable polymer actuator further comprises: a deformation controlling layer (5, 6) connected to the dielectric elastomeric film, wherein the deformation controlling layer at least locally has a higher stiffness than the dielectric elastomeric film, wherein the deformation controlling layer exhibits a spatially varying stiffness across the active portion in a stiffness pattern configured to control a curvature of the active portion when a voltage is applied between the first and second deformable electrodes, and wherein the controllable polymer actuator is optically transparent such that the controllable polymer actuator is switchable between optical states through application of the voltage between the electrodes. - a dielectric elastomeric film, - a first deformable electrode on a first side of the dielectric elastomeric film, and - a second deformable electrode on a second side of the dielectric elastomeric film, at least partly opposite the first deformable electrode, a deformation controlling layer (5, 6) connected to the dielectric elastomeric film,
A roller retainer cage for a roller thrust bearing, comprising: a first cage half including an annular portion, a first flange extending axially from an inner peripheral edge of the annular portion, and a second flange extending axially from an outer peripheral edge of the annular portion; and a second cage half (140, 140a) including an annular portion (142, 142a), a first flange (150, 150a) extending axially from one of an inner peripheral edge and an outer peripheral edge of the annular portion (142, 142a), a second flange (152, 152a) extending both axially and radially from the other of the inner peripheral edge and the outer peripheral edge, the second flange (152, 152a) including a first flange portion (154, 154a) and a second flange portion (156, 156a), wherein the second flange portion (156, 156a) of the second flange (152, 152a) of the second cage half (140, 140a) is disk-shaped, is disposed in a plane that is transverse to a longitudinal center axis of the roller retainer cage, and characterized in that the second flange portion (156, 156a) of the second flange (152, 152a) of the second cage half (140, 140a) extends radially toward the first flange (150, 150a) of the second cage half (140, 140a). a first cage half including an annular portion, a first flange extending axially from an inner peripheral edge of the annular portion, and a second flange extending axially from an outer peripheral edge of the annular portion; and a second cage half (140, 140a) including an annular portion (142, 142a), a first flange (150, 150a) extending axially from one of an inner peripheral edge and an outer peripheral edge of the annular portion (142, 142a), a second flange (152, 152a) extending both axially and radially from the other of the inner peripheral edge and the outer peripheral edge, the second flange (152, 152a) including a first flange portion (154, 154a) and a second flange portion (156, 156a), wherein the second flange portion (156, 156a) of the second flange (152, 152a) of the second cage half (140, 140a) is disk-shaped, is disposed in a plane that is transverse to a longitudinal center axis of the roller retainer cage, and characterized in that the second flange portion (156, 156a) of the second flange (152, 152a) of the second cage half (140, 140a) extends radially toward the first flange (150, 150a) of the second cage half (140, 140a).
A medication dispenser, comprising: - a first container for holding medication packages to be dispensed, and - conveying means for conveying medication packages from the first container to an outlet of the medication dispenser from which outlet a patient can take the medication packages, the conveying means comprising a first conveyor arranged in connection with the outlet and being capable of conveying a medication package in a first and a second conveying direction, so that a medication package can be conveyed to the outlet and retracted inside the medication dispenser; characterised in that the first conveyor comprises two opposing belt conveyors (141, 142) between which a medication package is arranged to be conveyed, both of the belt conveyors (141, 142) comprising an endless belt (145, 146) and a plurality of rollers (143, 143', 144, 144') around which the endless belt (145, 146) is arranged, and the first conveyor is arranged to be turnable about an axis between a first and a second position, wherein at the first position the first conveyor is capable of receiving a medication package from a second conveyor of the conveying means and at the second position the first conveyor is capable of conveying the medication package to a second container of the medication dispenser. - a first container for holding medication packages to be dispensed, and - conveying means for conveying medication packages from the first container to an outlet of the medication dispenser from which outlet a patient can take the medication packages, the conveying means comprising a first conveyor arranged in connection with the outlet and being capable of conveying a medication package in a first and a second conveying direction, so that a medication package can be conveyed to the outlet and retracted inside the medication dispenser;
A polymerizable liquid crystal material comprising a polymerizable liquid crystal compound, wherein an amount of a salt represented by the following formula is less than 0.01 parts by mass per 100 parts by mass of the polymerizable liquid crystal compound, and an amount of a nitrogen-containing compound represented by the following formula is 0.01 parts by mass or less per 100 parts by mass of the polymerizable liquid crystal compound, where R 1 to R 4 each independently represent a hydrogen atom or a C1-C7 alkyl group, and X represents F -, Br -, Cl -, I -, HSO 4 -, 1/2(HPO 4 2-), H 2 PO 4 -, R-C(=O)-O -, 1/2( - O-(C=O)-R'-(C=O)-O -) or R-SO 3 -, where R represents a hydrogen atom or a monovalent hydrocarbon group, and R' represents a single bond or a divalent hydrocarbon group, where R 5 represents a hydrogen atom or a C1-C7 alkyl group, and R 6 and R 7 represent a hydrogen atom. an amount of a salt represented by the following formula is less than 0.01 parts by mass per 100 parts by mass of the polymerizable liquid crystal compound, and an amount of a nitrogen-containing compound represented by the following formula is 0.01 parts by mass or less per 100 parts by mass of the polymerizable liquid crystal compound, where R 1 to R 4 each independently represent a hydrogen atom or a C1-C7 alkyl group, and X represents F -, Br -, Cl -, I -, HSO 4 -, 1/2(HPO 4 2-), H 2 PO 4 -, R-C(=O)-O -, 1/2( - O-(C=O)-R'-(C=O)-O -) or R-SO 3 -, where R represents a hydrogen atom or a monovalent hydrocarbon group, and R' represents a single bond or a divalent hydrocarbon group, where R 5 represents a hydrogen atom or a C1-C7 alkyl group, and R 6 and R 7 represent a hydrogen atom.