A fluidic device for producing activatable platelets from a suspension of megakaryocytes, comprising: a production chamber comprising at least one channel delimited by non-porous walls, and at least one inlet opening at one end, in which an inflow suspension of cells comprising megakaryocytes or their fragments can be introduced, and one outlet opening at the other end, in which an outflow suspension containing activatable platelets can be collected; wherein at least one portion of the inner surface of the walls of said channel is textured with a plurality of obstacles, wherein said obstacles are posts with a substantially circular section of radius r, said posts being arranged on the inner surface of at least one portion of said channel to form a regular pattern with a hexagonal periodic structure, in particular wherein: (i) the radius r of each post is comprised between D cell /2 and (H-D cell /2), preferably between D cell /100 and 100xD cell, more preferably between D cell /10 and 10xD cell, (ii) the closest distance p between two post centers is at least equal to 2r, preferably comprised between (2r + D cell /10) and (2r + 100xD cell), more preferably between (2r + D cell) and (2r + 10xD cell), and (iii) the angle α, denoting the smallest angle defined by the longitudinal direction of the channel and one of the lattice vectors of the hexagonal Bravais lattice is defined such that: - when r ≥ D cell /2, α is comprised between arcsin r 10 p and arcsin 2 r p, or - when r < D cell /2, α is comprised between arcsin D cell 20 p and arcsin D cell p where: D cell is the mean diameter of the megakaryocytes in the inflow suspension, and H is the height of the at least one channel, namely the smallest distance measured between two opposite walls in a section of the channel. a production chamber comprising at least one channel delimited by non-porous walls, and at least one inlet opening at one end, in which an inflow suspension of cells comprising megakaryocytes or their fragments can be introduced, and one outlet opening at the other end, in which an outflow suspension containing activatable platelets can be collected; wherein at least one portion of the inner surface of the walls of said channel is textured with a plurality of obstacles, wherein said obstacles are posts with a substantially circular section of radius r, said posts being arranged on the inner surface of at least one portion of said channel to form a regular pattern with a hexagonal periodic structure, in particular wherein: (i) the radius r of each post is comprised between D cell /2 and (H-D cell /2), preferably between D cell /100 and 100xD cell, more preferably between D cell /10 and 10xD cell, (ii) the closest distance p between two post centers is at least equal to 2r, preferably comprised between (2r + D cell /10) and (2r + 100xD cell), more preferably between (2r + D cell) and (2r + 10xD cell), and (iii) the angle α, denoting the smallest angle defined by the longitudinal direction of the channel and one of the lattice vectors of the hexagonal Bravais lattice is defined such that: - when r ≥ D cell /2, α is comprised between arcsin r 10 p and arcsin 2 r p, or - when r < D cell /2, α is comprised between arcsin D cell 20 p and arcsin D cell p (i) the radius r of each post is comprised between D cell /2 and (H-D cell /2), preferably between D cell /100 and 100xD cell, more preferably between D cell /10 and 10xD cell, (ii) the closest distance p between two post centers is at least equal to 2r, preferably comprised between (2r + D cell /10) and (2r + 100xD cell), more preferably between (2r + D cell) and (2r + 10xD cell), and (iii) the angle α, denoting the smallest angle defined by the longitudinal direction of the channel and one of the lattice vectors of the hexagonal Bravais lattice is defined such that: - when r ≥ D cell /2, α is comprised between arcsin r 10 p and arcsin 2 r p, or - when r < D cell /2, α is comprised between arcsin D cell 20 p and arcsin D cell p - when r ≥ D cell /2, α is comprised between arcsin r 10 p and arcsin 2 r p, or - when r < D cell /2, α is comprised between arcsin D cell 20 p and arcsin D cell p where: D cell is the mean diameter of the megakaryocytes in the inflow suspension, and H is the height of the at least one channel, namely the smallest distance measured between two opposite walls in a section of the channel. D cell is the mean diameter of the megakaryocytes in the inflow suspension, and H is the height of the at least one channel, namely the smallest distance measured between two opposite walls in a section of the channel.