mhurhangee/ep-ind-claims huggingface dataset:
A computer-implemented method of determining an effect on the function of a protein based on individual genome sequence information of a subject, comprising the steps of: determining, by an evaluation system, gene sequence variation information of a gene encoding the protein by using individual genome sequence information; calculating, by the evaluation system, an individual protein damage score associated with the protein using [Equation 2], wherein [Equation 2] is: S g v 1,..., v n = ∏ i = 1 n v i w i 1 / ∑ i = 1 n w i wherein Sg is a protein damage score of a protein encoded by a gene g, n is the number of target sequence variations for analysis among sequence variations of the gene g, vi is a gene sequence variation score of an i th gene sequence variation, and wi is a weighting assigned to the gene sequence variation score vi of the i th gene sequence variation; and determining, by the evaluation system, the effect on the function of the protein based on the individual protein damage score. determining, by an evaluation system, gene sequence variation information of a gene encoding the protein by using individual genome sequence information; calculating, by the evaluation system, an individual protein damage score associated with the protein using [Equation 2], wherein [Equation 2] is: S g v 1,..., v n = ∏ i = 1 n v i w i 1 / ∑ i = 1 n w i wherein Sg is a protein damage score of a protein encoded by a gene g, n is the number of target sequence variations for analysis among sequence variations of the gene g, vi is a gene sequence variation score of an i th gene sequence variation, and wi is a weighting assigned to the gene sequence variation score vi of the i th gene sequence variation; and determining, by the evaluation system, the effect on the function of the protein based on the individual protein damage score.
Floor cleaning machine, comprising a base, a rocker which is arranged at the base via a first pivot bearing for pivotal movement about a first pivot axis, a sweeping roller which is arranged at the rocker via a rotary bearing for rotational movement about a rotary axis, a motor device for rotatably driving the sweeping roller, and a traction drive (84; 84'; 84"; 188) having a traction member (86; 86"; 196) for transmitting torque from the motor device to the sweeping roller, wherein the traction member (86; 86"; 196) comprises a load-side section (88; 192), characterized in that a lever is arranged at the base via a second pivot bearing for pivotal movement about a second pivot axis, in that the lever is articulated to the rocker, and in that a deflection element for the traction member (86; 86"; 196) is arranged at the lever, wherein the traction member (86; 86"; 196) is guided on the deflection element in the load-side section (88; 192).
An optical filter having a laterally variable transmission wavelength within a wavelength range of 900nm to 1700nm, the optical filter comprising: a bandpass filter comprising a stack of alternating first and second layers (211, 212) comprising first and second materials, respectively; a blocking filter comprising a stack of alternating third and fourth layers (213, 214), comprising third and fourth materials, respectively; wherein the first, second and fourth materials each comprise different materials, so that a refractive index of the first material is smaller than a refractive index of the second material, the refractive index of the second material is smaller than a refractive index of the fourth material, and an absorption coefficient of the second material is smaller than an absorption coefficient of the fourth material in the wavelength range of 900nm to 1700nm, wherein the first and second layers have laterally varying thicknesses for providing the laterally variable transmission wavelength, and wherein the third and fourth layers have laterally varying thicknesses coordinated with the laterally varying thicknesses of the first and second dielectric layers, for blocking wavelengths within the wavelength range that are larger or smaller than the laterally variable transmission wavelength. a bandpass filter comprising a stack of alternating first and second layers (211, 212) comprising first and second materials, respectively; a blocking filter comprising a stack of alternating third and fourth layers (213, 214), comprising third and fourth materials, respectively; wherein the first, second and fourth materials each comprise different materials, so that a refractive index of the first material is smaller than a refractive index of the second material, the refractive index of the second material is smaller than a refractive index of the fourth material, and an absorption coefficient of the second material is smaller than an absorption coefficient of the fourth material in the wavelength range of 900nm to 1700nm, wherein the first and second layers have laterally varying thicknesses for providing the laterally variable transmission wavelength, and wherein the third and fourth layers have laterally varying thicknesses coordinated with the laterally varying thicknesses of the first and second dielectric layers, for blocking wavelengths within the wavelength range that are larger or smaller than the laterally variable transmission wavelength.
A dental blank comprising: a material portion inserted into a seating portion that comprises a seating groove having a circular shape in a cross-section, the material portion comprising a plurality of outer contacting portions in contact with an inner side of the seating portion, and the material portion having a polygonal shape in a cross-section in which the polygonal shape distinct from the circular shape, wherein the plurality of outer contacting portions is in linear contact with an inner side surface of the seating portion along an insertion direction where the material portion is inserted into the seating groove, and a tool entrance portion that is a separation space between the seating groove and the material portion is formed due to a difference in shape between the circular shape of the seating groove and the polygonal shape of the material portion. a material portion inserted into a seating portion that comprises a seating groove having a circular shape in a cross-section, the material portion comprising a plurality of outer contacting portions in contact with an inner side of the seating portion, and the material portion having a polygonal shape in a cross-section in which the polygonal shape distinct from the circular shape, wherein the plurality of outer contacting portions is in linear contact with an inner side surface of the seating portion along an insertion direction where the material portion is inserted into the seating groove, and a tool entrance portion that is a separation space between the seating groove and the material portion is formed due to a difference in shape between the circular shape of the seating groove and the polygonal shape of the material portion.
Actuating means for the head restraint of a vehicle seat, at least part of which head restraint can be shifted from a comfort position into a safety position in the event of an accident, comprising limbs (3.1 to 3.4) which are expanded from an initial position as a consequence of pressure loading and therefore bring about a lengthening which can be transmitted to force transmission means, wherein the limbs (3.1 to 3.4) are connected to one another and/or to fastening elements by means of joints (6.1 to 6.3), characterized in that the joints (6.1 to 6.3) each have a long joint pin (8.3) and a short joint pin (8.2) which can be inserted axially into holes in order to form the joints (6.1 to 6.3).
A network device for Remote Direct Memory Access, RDMA, wherein the network device is configured to: generate an outgoing packet according to a QUIC request or event, and transmit the outgoing packet to another network device, wherein the outgoing packet is a Quick User datagram protocol Internet Connection, QUIC based, packet, which comprises a User Datagram Protocol, UDP, header, a QUIC header and a QUIC payload, wherein the UDP header of the outgoing packet comprises an indication that indicates that the QUIC payload of the outgoing packet comprises one or more RDMA transactions, wherein the QUIC payload of the outgoing packet comprises the one or more RDMA transactions, and wherein the outgoing packet has a version field indicating a version of the QUIC, wherein the version of the QUIC is a dedicated QUIC version number used to disable encryption. generate an outgoing packet according to a QUIC request or event, and transmit the outgoing packet to another network device, wherein the outgoing packet is a Quick User datagram protocol Internet Connection, QUIC based, packet, which comprises a User Datagram Protocol, UDP, header, a QUIC header and a QUIC payload, wherein the UDP header of the outgoing packet comprises an indication that indicates that the QUIC payload of the outgoing packet comprises one or more RDMA transactions, wherein the QUIC payload of the outgoing packet comprises the one or more RDMA transactions, and wherein the outgoing packet has a version field indicating a version of the QUIC, wherein the version of the QUIC is a dedicated QUIC version number used to disable encryption.
A leaky wave antenna comprising a plurality of antenna elements connected to a feed line, each antenna element comprising: - a cell of filled circular geometry adapted to operate, when driven in use, in the E01 mode, and - a delay loop (6, 6') configured for mode rotation: wherein each cell is coupled to the feed line in a stub configuration at a first point on a perimeter of the cell such that the feed line extends tangentially to the cell; and wherein the delay loop (6, 6') is attached to a side of the cell at points on the perimeter substantially opposite to the side containing the first point. - a cell of filled circular geometry adapted to operate, when driven in use, in the E01 mode, and - a delay loop (6, 6') configured for mode rotation: wherein each cell is coupled to the feed line in a stub configuration at a first point on a perimeter of the cell such that the feed line extends tangentially to the cell; and wherein the delay loop (6, 6') is attached to a side of the cell at points on the perimeter substantially opposite to the side containing the first point. wherein each cell is coupled to the feed line in a stub configuration at a first point on a perimeter of the cell such that the feed line extends tangentially to the cell; and wherein the delay loop (6, 6') is attached to a side of the cell at points on the perimeter substantially opposite to the side containing the first point.
Gas burner with a fan and a mixing device arranged on the intake side of the fan, said mixing device having an intake channel and a gas inlet and being suited to mixing the air taken in through the intake channel with a gas supplied to the intake channel through a gas inlet to form a gas-air mixture, wherein the mixing device has a housing with an air inlet which has cutouts (6, 7) for noise reduction, characterised in that the gas burner has a sound absorber which is connected to the air inlet and that the mixing device housing is connected to the sound absorber in the form of a plug-in connection or a screw connection.
Inflatable balloon, designed to be implanted in a body cavity, comprising: - a pouch formed of a sealed wall delimiting an internal space; - a valve for filling the internal space with a fluid, capable of being occluded after filling the internal space; the pouch delimiting a fluid-draining orifice opening into the internal space, the balloon comprising an element that occludes the draining orifice, the occluding element being capable of releasing the draining orifice under the effect of a magnetic field, so as to enable the at least partial drainage of the fluid contained in the internal space, characterized in that the occluding element is movable along at least two distinct axes in relation to the pouch. - a pouch formed of a sealed wall delimiting an internal space; - a valve for filling the internal space with a fluid, capable of being occluded after filling the internal space;
A circular knitted garment (10, 42, 60, 98, 100) for a lower torso, the garment comprising: a tubular fabric body (12, 62) comprising a fabric front, a fabric back, a tube top, a tube bottom, and a bottom edge; a front arched cutout (18, 48) along at least a portion of the bottom edge of the fabric front of the tubular fabric body, said front arched cutout having a front arched cutout height along a vertical axis (y) of the tubular fabric body, wherein the front arched cutout comprises a front arched cutout edge; and a back arched cutout along at least a portion of the bottom edge of the fabric back of the tubular fabric body, said back arched cutout having a back arched cutout height along a vertical axis of the tubular fabric body, and further wherein the back arched cutout comprises a back arched cutout edge, wherein the front arched cutout edge is coupled to the back arched cutout edge to provide an inseam, a right leg, and a left leg and, wherein the inseam, the right leg, and the left leg are formed from at least a portion of the tubular fabric body, characterized in that the front arched cutout height is greater than the back arched cutout height.
A method for antivirus scanning, on a proxy server, of data downloaded from a data server via a network to a PC workstation, the method comprising the steps of: - computing, by a data analysis module of the proxy server, an overall probability that the downloaded data contains malicious code; - if the overall probability that the downloaded data contains malicious code is high, fully downloading the data from the data server into a cache of the proxy server; performing, by an antivirus module of the proxy server, an antivirus scan; if malicious code is detected, attempting, by the antivirus module, to treat the infection of the downloaded data; and if the treatment is successful, then transmitting the data to the PC workstation from the cache; - if the overall probability that the downloaded data contains malicious code is low, scanning, by the antivirus module of the proxy server, the data while it is being transferred to the PC workstation; wherein, upon detection of malicious code in the data, the antivirus module transmits instructions for performing the treatment along with an indication that the data is infected to the PC workstation. - computing, by a data analysis module of the proxy server, an overall probability that the downloaded data contains malicious code; - if the overall probability that the downloaded data contains malicious code is high, fully downloading the data from the data server into a cache of the proxy server; performing, by an antivirus module of the proxy server, an antivirus scan; if malicious code is detected, attempting, by the antivirus module, to treat the infection of the downloaded data; and if the treatment is successful, then transmitting the data to the PC workstation from the cache; fully downloading the data from the data server into a cache of the proxy server; performing, by an antivirus module of the proxy server, an antivirus scan; if malicious code is detected, attempting, by the antivirus module, to treat the infection of the downloaded data; and if the treatment is successful, then transmitting the data to the PC workstation from the cache; - if the overall probability that the downloaded data contains malicious code is low, scanning, by the antivirus module of the proxy server, the data while it is being transferred to the PC workstation; wherein, upon detection of malicious code in the data, the antivirus module transmits instructions for performing the treatment along with an indication that the data is infected to the PC workstation. scanning, by the antivirus module of the proxy server, the data while it is being transferred to the PC workstation; wherein, upon detection of malicious code in the data, the antivirus module transmits instructions for performing the treatment along with an indication that the data is infected to the PC workstation.
A shoe, comprising: an upper configured to receive therein a foot of a wearer of the shoe, the upper comprising a closure and a tongue configured to cover a top portion of the foot; at least one wire lace coupled to opposing edges of the closure and configured to pull the opposing edges of the closure closer together to tighten the closure around the foot; at least one support wire coupled to the at least one wire lace, wherein the at least one support wire wraps around a lateral, bottom and medial side of the upper such that when the at least one wire lace tightens the closure around the foot, the at least one support wire tightens around the lateral, bottom and medial sides of the upper, characterized by a first coupling mechanism coupled to a first opposing edge of the closure and to the at least one wire lace and disposed on the first opposing edge of the closure; and a second coupling mechanism coupled to a second opposing edge of the closure and to the at least one wire lace and disposed on the second opposing edge of the closure, wherein the first and second coupling mechanisms couple the at least one wire lace to the at least one support wire, wherein the at least one support wire comprises a first support wire, the first support wire having a first end coupled to the first coupling mechanism and a second end coupled to the second coupling mechanism. an upper configured to receive therein a foot of a wearer of the shoe, the upper comprising a closure and a tongue configured to cover a top portion of the foot; at least one wire lace coupled to opposing edges of the closure and configured to pull the opposing edges of the closure closer together to tighten the closure around the foot; at least one support wire coupled to the at least one wire lace, wherein the at least one support wire wraps around a lateral, bottom and medial side of the upper such that when the at least one wire lace tightens the closure around the foot, the at least one support wire tightens around the lateral, bottom and medial sides of the upper, characterized by a first coupling mechanism coupled to a first opposing edge of the closure and to the at least one wire lace and disposed on the first opposing edge of the closure; and a second coupling mechanism coupled to a second opposing edge of the closure and to the at least one wire lace and disposed on the second opposing edge of the closure, wherein the first and second coupling mechanisms couple the at least one wire lace to the at least one support wire, wherein the at least one support wire comprises a first support wire, the first support wire having a first end coupled to the first coupling mechanism and a second end coupled to the second coupling mechanism.
A head-up display, comprising a laser light source, a micro-electro-mechanical system, a diffuser film, and an apparatus for detecting a shift of the diffuser film, wherein the apparatus comprises a power supply, a conductive module, and a detection module; a relatively fixed position relationship exists between the conductive module and the diffuser film; when the diffuser film is in a first position, the conductive module is connected to the power supply to form a closed loop; when the diffuser film is shifted from the first position to a second position, a position of the conductive module changes to make the closed loop open; a shift distance from the second position to the first position is greater than a preset distance; the detection module is configured to detect that the closed loop is opened; the diffuser film is fastened to a bearer module; the conductive module is connected to the bearer module; the bearer module comprises a first frame; the diffuser film is in the first frame, and the diffuser film is adhered to the first frame; the conductive module is fastened to the first frame; the bearer module further comprises a foot; the foot is connected to the first frame, and is configured to support the first frame; the conductive module is disposed below the foot and connected to the foot; when the diffuser film is in the first position, laser light emitted by the laser light source is scanned by the micro-electro-mechanical system and incident on the diffuser film; and when the diffuser film is in the second position, the diffuser film deviates from an optical path of the laser light scanned by the micro-electro-mechanical system. the apparatus comprises a power supply, a conductive module, and a detection module; a relatively fixed position relationship exists between the conductive module and the diffuser film; when the diffuser film is in a first position, the conductive module is connected to the power supply to form a closed loop; when the diffuser film is shifted from the first position to a second position, a position of the conductive module changes to make the closed loop open; a shift distance from the second position to the first position is greater than a preset distance; the detection module is configured to detect that the closed loop is opened; the diffuser film is fastened to a bearer module; the conductive module is connected to the bearer module; the bearer module comprises a first frame; the diffuser film is in the first frame, and the diffuser film is adhered to the first frame; the conductive module is fastened to the first frame; the bearer module further comprises a foot; the foot is connected to the first frame, and is configured to support the first frame; the conductive module is disposed below the foot and connected to the foot; when the diffuser film is in the first position, laser light emitted by the laser light source is scanned by the micro-electro-mechanical system and incident on the diffuser film; and when the diffuser film is in the second position, the diffuser film deviates from an optical path of the laser light scanned by the micro-electro-mechanical system.
An oligonucleotide-based compound comprising two single-stranded antisense oligonucleotides linked at their 5'-ends, wherein the oligonucleotide-based compound has two accessible 3'-ends.