A Raman spectrum detecting method for eliminating package interference, characterized in that the method comprises steps of: detecting a Raman spectrum of a package to obtain a Raman spectrum signal representing the Raman spectrum of the package; detecting a Raman spectrum of an object in the package passing through the package to obtain a Raman spectrum signal representing the Raman spectrum of the object together with the package; subtracting a product of a proportionality coefficient and the Raman spectrum signal of the package from the Raman spectrum signal of the object together with the package, and successively changing the proportionality coefficient to successively subtract the Raman spectrum signal of the package from the Raman spectrum signal of the object together with the package to obtain a series of package-interference-eliminated Raman spectrum signals; calculating an information entropy of each of the series of package-interference-eliminated Raman spectrum signals and an information entropy of the Raman spectrum signal of the package; comparing the information entropies of the series of package-interference-eliminated Raman spectrum signals with the information entropy of the Raman spectrum signal of the package, setting the information entropies of package-interference-eliminated Raman spectrum signals that are each greater than the information entropy of the Raman spectrum signal of the package into an information entropy sequence to be selected, and selecting a minimum information entropy from the information entropy sequence; and using the package-interference-eliminated Raman spectrum signal corresponding to the minimum information entropy as an optimized package-interference-eliminated Raman spectrum signal. detecting a Raman spectrum of a package to obtain a Raman spectrum signal representing the Raman spectrum of the package; detecting a Raman spectrum of an object in the package passing through the package to obtain a Raman spectrum signal representing the Raman spectrum of the object together with the package; subtracting a product of a proportionality coefficient and the Raman spectrum signal of the package from the Raman spectrum signal of the object together with the package, and successively changing the proportionality coefficient to successively subtract the Raman spectrum signal of the package from the Raman spectrum signal of the object together with the package to obtain a series of package-interference-eliminated Raman spectrum signals; calculating an information entropy of each of the series of package-interference-eliminated Raman spectrum signals and an information entropy of the Raman spectrum signal of the package; comparing the information entropies of the series of package-interference-eliminated Raman spectrum signals with the information entropy of the Raman spectrum signal of the package, setting the information entropies of package-interference-eliminated Raman spectrum signals that are each greater than the information entropy of the Raman spectrum signal of the package into an information entropy sequence to be selected, and selecting a minimum information entropy from the information entropy sequence; and using the package-interference-eliminated Raman spectrum signal corresponding to the minimum information entropy as an optimized package-interference-eliminated Raman spectrum signal.