mhurhangee/ep-ind-claims huggingface dataset:
A system for detecting particles in a fluid, the system comprising: a flow cell (210, 620) for flowing a fluid containing particles along a flow direction through a beam (222, 320, 605) of electromagnetic radiation, an optical source (220, 600) in optical communication with the flow cell for providing the beam (222, 320, 605) of electromagnetic radiation; a focusing system (221, 275, 300, 610) in optical communication with the optical source (220, 600) for focusing said beam (222, 320, 605) of electromagnetic radiation to generate an area of high radiation density within said flow cell (210, 620); and an optical collection system (265, 267, 610b) for collecting and directing at least a portion of electromagnetic radiation onto a pixelated photodetector (268, 240, 650), wherein the pixelated photodetector (268, 240, 650) is configured to produce an electric signal characteristic of the number and/or size of the particles detected and characterized in that, for at least a portion of the pixels of said pixelated photodetector (268, 240, 650), each pixel: has an area corresponding to a spatial extent of the particle beam interaction signal within the beam (222, 320, 605). a flow cell (210, 620) for flowing a fluid containing particles along a flow direction through a beam (222, 320, 605) of electromagnetic radiation, an optical source (220, 600) in optical communication with the flow cell for providing the beam (222, 320, 605) of electromagnetic radiation; a focusing system (221, 275, 300, 610) in optical communication with the optical source (220, 600) for focusing said beam (222, 320, 605) of electromagnetic radiation to generate an area of high radiation density within said flow cell (210, 620); and an optical collection system (265, 267, 610b) for collecting and directing at least a portion of electromagnetic radiation onto a pixelated photodetector (268, 240, 650), wherein the pixelated photodetector (268, 240, 650) is configured to produce an electric signal characteristic of the number and/or size of the particles detected and characterized in that, for at least a portion of the pixels of said pixelated photodetector (268, 240, 650), each pixel: has an area corresponding to a spatial extent of the particle beam interaction signal within the beam (222, 320, 605).
An apparatus comprising: a piezoelectric convertor layer; at least one piezoresistive layer on the piezoelectric convertor layer, where the at least one piezoresistive layer comprises a plurality of spaced apart piezoresistive electrodes, where the apparatus is configured such that when the piezoelectric convertor layer is deformed to generate a charge, at least one of the piezoresistive electrodes is stressed, where the at least one piezoresistive layer is configured to control flow of charge from the piezoelectric convertor layer; and electrical conductor outputs electrically connected to the piezoresistive electrodes, where the outputs are configured to allow the charge from the piezoelectric convertor layer to flow out of the piezoresistive electrodes, where the electrical conductor outputs are configured relative to the piezoresistive electrodes to allow identification of the at least one piezoresistive electrode which has been stressed based upon the charge on at least one of the electrical conductor outputs. a piezoelectric convertor layer; at least one piezoresistive layer on the piezoelectric convertor layer, where the at least one piezoresistive layer comprises a plurality of spaced apart piezoresistive electrodes, where the apparatus is configured such that when the piezoelectric convertor layer is deformed to generate a charge, at least one of the piezoresistive electrodes is stressed, where the at least one piezoresistive layer is configured to control flow of charge from the piezoelectric convertor layer; and electrical conductor outputs electrically connected to the piezoresistive electrodes, where the outputs are configured to allow the charge from the piezoelectric convertor layer to flow out of the piezoresistive electrodes, where the electrical conductor outputs are configured relative to the piezoresistive electrodes to allow identification of the at least one piezoresistive electrode which has been stressed based upon the charge on at least one of the electrical conductor outputs.
A rolling bearing device equipped with an IC tag, which comprises an outer race and an inner race, one or each of which races (1, 2) has a hole (6, 7, 20) formed in a surface portion thereof, wherein the or each hole (6, 7, 20) has an IC tag capable of non-contact communication retained therein through a shock-absorbing body made of an elastic rubber material, wherein the shock-absorbing body is provided at the opening of the hole (6, 7, 20) so as to cover the IC tag like a lid, thereby sealing the IC tag, and wherein a surface of the or each race (1, 2) in which the hole (6, 7, 20) is formed is a surface for receiving a preload for attaching the rolling bearing device to a target object.
A differentially pumped vacuum system comprising a plurality of pressure chambers (11, 12, 14, 10); and a vacuum pump attached thereto and comprising a plurality of pump inlets (124, 122, 120) each for receiving fluid from a respective pressure chamber, and a plurality of pumping stages (112, 108, 106) for differentially pumping the chambers; Characterized in that a pumping stage arranged to pump fluid from the pressure chamber in which the highest pressure is to be generated comprises a Gaede stage.
An in vitro method of making recombinant cells comprising: contacting cells comprising a target sequence to be deleted within a CCR5 receptor gene with an effector oligonucleotide targeted to the CCR5 receptor gene, wherein the effector oligonucleotide comprises 10 to 200 bases matching 10 to 200 bases of the CCR5 receptor gene sequence before the target sequence to be deleted and 10 to 200 bases matching 10 to 200 bases of the CCR5 receptor gene after the target sequence to be deleted, contacting the cell with triplex-forming oligonucleotides or pseudocomplementary oligonucleotides; and allowing the effector oligonucleotide to delete the target sequence in the cells, wherein the sequence to be deleted is a Δ32 deletion. contacting cells comprising a target sequence to be deleted within a CCR5 receptor gene with an effector oligonucleotide targeted to the CCR5 receptor gene, wherein the effector oligonucleotide comprises 10 to 200 bases matching 10 to 200 bases of the CCR5 receptor gene sequence before the target sequence to be deleted and 10 to 200 bases matching 10 to 200 bases of the CCR5 receptor gene after the target sequence to be deleted, contacting the cell with triplex-forming oligonucleotides or pseudocomplementary oligonucleotides; and allowing the effector oligonucleotide to delete the target sequence in the cells, wherein the sequence to be deleted is a Δ32 deletion.
A method for producing a medicinal product comprising a biologically active protein comprising the steps of: - providing an aqueous composition comprising a solvent, the biologically active protein and between 20% w/w and 60% w/w of a non-polymeric sugar, - freezing the composition, thereby forming at least one frozen body comprising the solvent in frozen form, - putting the frozen body in a drying apparatus while being carried by a support, the support comprising one or more restraining elements that define one or more boundaries of the support, wherein at most 30% of the surface of the body is contiguous with the one or more restraining elements, - reducing the pressure in the drying apparatus below atmospheric pressure, - providing heat to the body in order to sublimate the frozen solvent of the body and obtain a dried body, the freeze-dried body having a volume between 50 and 1000 μl. - providing an aqueous composition comprising a solvent, the biologically active protein and between 20% w/w and 60% w/w of a non-polymeric sugar, - freezing the composition, thereby forming at least one frozen body comprising the solvent in frozen form, - putting the frozen body in a drying apparatus while being carried by a support, the support comprising one or more restraining elements that define one or more boundaries of the support, wherein at most 30% of the surface of the body is contiguous with the one or more restraining elements, - reducing the pressure in the drying apparatus below atmospheric pressure, - providing heat to the body in order to sublimate the frozen solvent of the body and obtain a dried body, the freeze-dried body having a volume between 50 and 1000 μl.
An apparatus for releasing chemical agents in a well bore, comprising: a chemical package comprising: a packaging material; a chemical agent, wherein the chemical agent is contained within the packaging material; and a chemical adhesive or magnet, wherein the chemical adhesive or magnet is attached to the packaging material, wherein the apparatus is attached to a tubular by the chemical adhesive or magnet, wherein the chemical package defines a first side of the apparatus and the chemical adhesive or magnet defines a second side of the apparatus opposite to the first side; and wherein the apparatus further comprises a pressure activated release mechanism comprising: a housing; a flexible ring disposed between the chemical package and the chemical adhesive or magnet such that, at atmospheric conditions, an air gap is formed between the chemical package and the chemical adhesive or magnet; and a plurality of puncture points disposed between the chemical package and the chemical adhesive or magnet such that, at a selected pressure, the air gap compresses to allow the plurality of puncture points to pierce the chemical package. a packaging material; a chemical agent, wherein the chemical agent is contained within the packaging material; and a chemical adhesive or magnet, wherein the chemical adhesive or magnet is attached to the packaging material, wherein the apparatus is attached to a tubular by the chemical adhesive or magnet, wherein the chemical package defines a first side of the apparatus and the chemical adhesive or magnet defines a second side of the apparatus opposite to the first side; and wherein the apparatus further comprises a pressure activated release mechanism comprising: a housing; a flexible ring disposed between the chemical package and the chemical adhesive or magnet such that, at atmospheric conditions, an air gap is formed between the chemical package and the chemical adhesive or magnet; and a plurality of puncture points disposed between the chemical package and the chemical adhesive or magnet such that, at a selected pressure, the air gap compresses to allow the plurality of puncture points to pierce the chemical package. a housing; a flexible ring disposed between the chemical package and the chemical adhesive or magnet such that, at atmospheric conditions, an air gap is formed between the chemical package and the chemical adhesive or magnet; and a plurality of puncture points disposed between the chemical package and the chemical adhesive or magnet such that, at a selected pressure, the air gap compresses to allow the plurality of puncture points to pierce the chemical package.
Method for heating an electrically heatable catalytic converter (46, 105) for exhaust-gas aftertreatment in an internal combustion engine which is connected by way of its outlet to an exhaust-gas system, wherein the electrically heatable catalytic converter (46, 105) is arranged in the exhaust-gas system, wherein the method comprises the following steps: electrically heating the electrically heatable catalytic converter (46, 105) and increasing the rotation speed of the internal combustion engine to at least 1000 rpm, wherein: the steps of the method are carried out during idling of the internal combustion engine; during the method steps drive-away restriction for a motor vehicle driven by the internal combustion engine is activated; and the drive-away restriction is visually displayed to the driver. electrically heating the electrically heatable catalytic converter (46, 105) and increasing the rotation speed of the internal combustion engine to at least 1000 rpm, wherein: the steps of the method are carried out during idling of the internal combustion engine; during the method steps drive-away restriction for a motor vehicle driven by the internal combustion engine is activated; and the drive-away restriction is visually displayed to the driver. the steps of the method are carried out during idling of the internal combustion engine; during the method steps drive-away restriction for a motor vehicle driven by the internal combustion engine is activated; and the drive-away restriction is visually displayed to the driver.
Method for cleaning and/or disinfecting of sealing elements of a sealing machine or of a sealing assembly, wherein, during a cleaning mode, at least one cleaning and/or disinfection medium, which is supplied to the sealing element via at least one coupling piece, flows through and around the interior chamber of the respective sealing element and the functional elements therein, and the sealing tool serving to attach the respective closure onto a container, wherein the treatment of the sealing elements during the cleaning mode takes place one after another, in each case individually or in sealing element groups of at least two sealing elements, wherein, for this purpose, the sealing elements or sealing element groups, by way of a drive which allows for a stepped further movement of the rotor, move to a docking or cleaning station, which comprises the at least one coupling piece, wherein the at least one coupling piece is connected to the respective sealing element located at the cleaning station by mechanical delivery and coupling, and wherein, after the completion of the treatment of the respective sealing element, the at least one coupling piece is removed, again by mechanical means, from the respective sealing element, characterised in that for the removal of the at least one cleaning and/or disinfection medium, at least one further coupling piece of the cleaning station is mechanically coupled to the sealing element arranged at this station, and after the treatment is mechanically removed again from the sealing element.
An antibody specifically binding to human c-Kit comprising a mature heavy chain variable region that has a sequence of SEQ ID NO: 13 except that position 1 can be E, and a mature light chain variable region that has a sequence of SEQ ID NO: 53.
An ApoCIII specific inhibitor for use in a method of i) treating, preventing, delaying or ameliorating Lipoprotein lipase deficiency (LPLD) or Familial Chylomicronemia Syndrome in an animal; or ii) preventing, delaying or ameliorating pancreatitis, or symptom thereof in an animal with LPLD or FCS, wherein the ApoCIII specific inhibitor comprises an antisense compound targeting ApoCIII, wherein the antisense compound is an interfering RNA compound.
A hemostatic composition in powder form comprising: - collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen, said collagen being in a content ranging from 70% to 99% by weight relative to the total weight of the composition, - at least one monosaccharide in a content ranging from 1% to 12.5% by weight relative to the total weight of the composition, and - at least one coagulation factor in a content ranging from 0.01 IU/mg to 20 IU/mg. - collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen, said collagen being in a content ranging from 70% to 99% by weight relative to the total weight of the composition, - at least one monosaccharide in a content ranging from 1% to 12.5% by weight relative to the total weight of the composition, and - at least one coagulation factor in a content ranging from 0.01 IU/mg to 20 IU/mg.
An electronic device comprising: a touchscreen; a voice recognition module; and a controlled configured to: receive a voice input through the voice recognition module when the voice recognition module has been activated, convert the voice input into text and display the converted text on the touch screen, display an object indicator for editing a preset word included in the text upon recognizing the preset word while displaying the converted text on the touch screen, wherein the preset word is a long syllable, wherein the object indicator is an GUI for guide to editing the preset word, and is displayed at a location where the preset word is recognized, receive an input for selecting the object indicator, provide an editing option for changing the displayed object indicator into new text to be displayed on the touchscreen, and display the new text when the editing option is selected, the new text includes symbols 1 for inserting or replacing the long syllable. a touchscreen; a voice recognition module; and a controlled configured to: receive a voice input through the voice recognition module when the voice recognition module has been activated, convert the voice input into text and display the converted text on the touch screen, display an object indicator for editing a preset word included in the text upon recognizing the preset word while displaying the converted text on the touch screen, wherein the preset word is a long syllable, wherein the object indicator is an GUI for guide to editing the preset word, and is displayed at a location where the preset word is recognized, receive an input for selecting the object indicator, provide an editing option for changing the displayed object indicator into new text to be displayed on the touchscreen, and display the new text when the editing option is selected, the new text includes symbols 1 for inserting or replacing the long syllable. receive a voice input through the voice recognition module when the voice recognition module has been activated, convert the voice input into text and display the converted text on the touch screen, display an object indicator for editing a preset word included in the text upon recognizing the preset word while displaying the converted text on the touch screen, wherein the preset word is a long syllable, wherein the object indicator is an GUI for guide to editing the preset word, and is displayed at a location where the preset word is recognized, receive an input for selecting the object indicator, provide an editing option for changing the displayed object indicator into new text to be displayed on the touchscreen, and display the new text when the editing option is selected, the new text includes symbols 1 for inserting or replacing the long syllable.
An endoscopic instrument, comprising: a housing including an elongated shaft assembly extending distally therefrom, the elongated shaft assembly having inner and outer shaft members, the inner ( and outer shaft members removably coupled to the housing and the outer shaft member movable with respect to the inner shaft member; an end effector operably supported at the distal end of the outer shaft member; a bushing operably coupled to the inner and outer shaft members of the shaft assembly and selectively and releasably coupled to the housing, wherein the bushing includes at least one resilient finger configured to engage at least one slot defined through the inner shaft member and at least one slot defined through the outer shaft member to release the inner and outer shaft members from the housing; characterised in that it further comprises a spring carrier including at least one resilient boss configured to releasably engage at least one second slot defined through the outer shaft member at a proximal end thereof and configured to release the inner and outer shaft members from the housing when the outer shaft member is rotated with respect to the spring carrier, the spring carrier further configured to provide axial movement of the outer shaft member when a handle assembly of the endoscopic instrument is actuated. a housing including an elongated shaft assembly extending distally therefrom, the elongated shaft assembly having inner and outer shaft members, the inner ( and outer shaft members removably coupled to the housing and the outer shaft member movable with respect to the inner shaft member; an end effector operably supported at the distal end of the outer shaft member; a bushing operably coupled to the inner and outer shaft members of the shaft assembly and selectively and releasably coupled to the housing, wherein the bushing includes at least one resilient finger configured to engage at least one slot defined through the inner shaft member and at least one slot defined through the outer shaft member to release the inner and outer shaft members from the housing; characterised in that it further comprises a spring carrier including at least one resilient boss configured to releasably engage at least one second slot defined through the outer shaft member at a proximal end thereof and configured to release the inner and outer shaft members from the housing when the outer shaft member is rotated with respect to the spring carrier, the spring carrier further configured to provide axial movement of the outer shaft member when a handle assembly of the endoscopic instrument is actuated.
A connector connecting a conductor portion of an electric wire to a connection object, the connector comprising: a housing (13, 23, 33, 43) accommodating an end of the connection object and an end of the electric wire, wherein the connection object and the conductor portion of the electric wire make contact with and are electrically connected to each other in the housing, the housing has an electric wire lead-out port (13F, 23F, 33F, 43F) leading out the electric wire from inside to outside of the housing, the connector being characterized in that: the electric wire lead-out port has a first contact portion and a second contact portion that make contact with the electric wire at a first contact point of the first contact portion and a second contact point of the second contact portion separate away from each other along a length direction of the electric wire so as to disperse a load applied to the electric wire when the electric wire is led out from the housing at a predetermined minimum bending radius determined by a shape of the housing around the electric wire lead-out port and wherein the electric wire lead-out port is situated away from the electric wire at a tapered portion between the first and second contact points (P1, P2). a housing (13, 23, 33, 43) accommodating an end of the connection object and an end of the electric wire, wherein the connection object and the conductor portion of the electric wire make contact with and are electrically connected to each other in the housing, the housing has an electric wire lead-out port (13F, 23F, 33F, 43F) leading out the electric wire from inside to outside of the housing, the connector being characterized in that: the electric wire lead-out port has a first contact portion and a second contact portion that make contact with the electric wire at a first contact point of the first contact portion and a second contact point of the second contact portion separate away from each other along a length direction of the electric wire so as to disperse a load applied to the electric wire when the electric wire is led out from the housing at a predetermined minimum bending radius determined by a shape of the housing around the electric wire lead-out port and wherein the electric wire lead-out port is situated away from the electric wire at a tapered portion between the first and second contact points (P1, P2).