A method for preparing the ginseng-derived nanoparticles having a membrane structure characterized by comprising the following steps: squeezing fresh and washed ginseng by low-speed screw extrusion to obtain a slurry, wherein the rotation speed of the low-speed screw extrusion is 30 to 60 rpm; filtering the slurry obtained in step through a sieve to remove impurities and collecting a filtrate; sequentially subjecting the filtrate obtained in step to low-speed, medium-speed, high-speed, and ultra-speed centrifugation, discarding a precipitate after each centrifugation, and collecting a supernatant for the next centrifugation, wherein a precipitate is collected after the last centrifugation; wherein for the low-speed centrifugation, the centrifugal force is 100 to 500 x g, and the centrifugation time is 5 to 10 minutes; for the medium-speed centrifugation, the centrifugal force is 1,000 to 5,000 x g, and the centrifugation time is 10 to 30 minutes; for the high-speed centrifugation, the centrifugal force is 8,000 to 12,000 x g, and the centrifugation time is 30 to 60 minutes; for the ultra-speed centrifugation, the centrifugal force is 100,000 to 200,000 x g, and the centrifugation time is 60 to 120 minutes, the number of each of the low-speed, medium-speed, high-speed and ultra-speed centrifugation is at least one. resuspending the precipitate collected by the last centrifugation in step with a buffer, then subjecting a mixture to ultra-speed centrifugation once, and collecting a precipitate; resuspending the precipitate with a buffer again, then subjecting a mixture to high-speed centrifugation and collecting a supernatant; passing the supernatant through a sterilizing grade filter membrane to obtain the ginseng-derived nanoparticle. squeezing fresh and washed ginseng by low-speed screw extrusion to obtain a slurry, wherein the rotation speed of the low-speed screw extrusion is 30 to 60 rpm; filtering the slurry obtained in step through a sieve to remove impurities and collecting a filtrate; sequentially subjecting the filtrate obtained in step to low-speed, medium-speed, high-speed, and ultra-speed centrifugation, discarding a precipitate after each centrifugation, and collecting a supernatant for the next centrifugation, wherein a precipitate is collected after the last centrifugation; wherein for the low-speed centrifugation, the centrifugal force is 100 to 500 x g, and the centrifugation time is 5 to 10 minutes; for the medium-speed centrifugation, the centrifugal force is 1,000 to 5,000 x g, and the centrifugation time is 10 to 30 minutes; for the high-speed centrifugation, the centrifugal force is 8,000 to 12,000 x g, and the centrifugation time is 30 to 60 minutes; for the ultra-speed centrifugation, the centrifugal force is 100,000 to 200,000 x g, and the centrifugation time is 60 to 120 minutes, the number of each of the low-speed, medium-speed, high-speed and ultra-speed centrifugation is at least one. resuspending the precipitate collected by the last centrifugation in step with a buffer, then subjecting a mixture to ultra-speed centrifugation once, and collecting a precipitate; resuspending the precipitate with a buffer again, then subjecting a mixture to high-speed centrifugation and collecting a supernatant; passing the supernatant through a sterilizing grade filter membrane to obtain the ginseng-derived nanoparticle.