mhurhangee/ep-ind-claims huggingface dataset:
A double-stranded ribonucleic acid (dsRNA) for inhibiting expression of an APOC3 gene, wherein the dsRNA comprises (a) a sense strand consisting of the nucleotide sequence GcuuAAAAGGGAcAGuAuudTsdT and an antisense strand consisting of a nucleotide sequence AAuACUGUCCCUUUuAAGCdTsdT, (b) a sense strand consisting of the nucleotide sequence GCUUAAAAGGGACAGUAUUdTsdT and an antisense strand consisting of a nucleotide sequence AAUACUGUCCCUUUUAAGCdTsdT, (c) a sense strand consisting of the nucleotide sequence GfcUfuAfaAfaGfgGfaCfaGfuAfuUfdTsdT and an antisense strand consisting of a nucleotide sequence aAfuAfcUfgUfcCfcUfuUfuAfaGfcdTsdT, or (d) a sense strand consisting of the nucleotide sequence GcuuAAAAGGGAcAGuAuudTsdT and an antisense strand consisting of a nucleotide sequence AAuACuGUCCCuuuuAagcdTsdT, wherein lower case nucleotides are 2'-O-methyl nucleotides; Gf, Af, Uf and Cf are 2'-fluoro nucleotides; and s is a phosphothioate linkage. (a) a sense strand consisting of the nucleotide sequence GcuuAAAAGGGAcAGuAuudTsdT and an antisense strand consisting of a nucleotide sequence AAuACUGUCCCUUUuAAGCdTsdT, (b) a sense strand consisting of the nucleotide sequence GCUUAAAAGGGACAGUAUUdTsdT and an antisense strand consisting of a nucleotide sequence AAUACUGUCCCUUUUAAGCdTsdT, (c) a sense strand consisting of the nucleotide sequence GfcUfuAfaAfaGfgGfaCfaGfuAfuUfdTsdT and an antisense strand consisting of a nucleotide sequence aAfuAfcUfgUfcCfcUfuUfuAfaGfcdTsdT, or (d) a sense strand consisting of the nucleotide sequence GcuuAAAAGGGAcAGuAuudTsdT and an antisense strand consisting of a nucleotide sequence AAuACuGUCCCuuuuAagcdTsdT, wherein lower case nucleotides are 2'-O-methyl nucleotides; Gf, Af, Uf and Cf are 2'-fluoro nucleotides; and s is a phosphothioate linkage.
Method for controlling a start-up process of a vehicle, comprising at least the following steps: a) activating a control sequence and setting a control sequence signal before a first slip occurs, b) defining a maximum engine drive torque (M4_max) that is less than a maximum engine drive torque when the control sequence is deactivated, c) when a driving request for a start-up process is detected - c1) actuating a clutch-transmission unit with an engagement process duration (tc) greater than a standard engagement process duration (tcs) provided when the control sequence is deactivated, - c2) while controlling wheel slip (ms) of the driven wheels (4a, 4b) by determining wheel speeds (n4a, n4b) of the driven wheels (4a, 4b) and at least adjusting an output drive torque at the output shaft, - c3) redefining the maximum engine drive torque (M4_max) according to the wheel slip (ms) and a driving speed (v), and d) deactivating the control sequence and resetting the control sequence signal when limit values (μ_tres, v_tres) are reached. a) activating a control sequence and setting a control sequence signal before a first slip occurs, b) defining a maximum engine drive torque (M4_max) that is less than a maximum engine drive torque when the control sequence is deactivated, c) when a driving request for a start-up process is detected - c1) actuating a clutch-transmission unit with an engagement process duration (tc) greater than a standard engagement process duration (tcs) provided when the control sequence is deactivated, - c2) while controlling wheel slip (ms) of the driven wheels (4a, 4b) by determining wheel speeds (n4a, n4b) of the driven wheels (4a, 4b) and at least adjusting an output drive torque at the output shaft, - c3) redefining the maximum engine drive torque (M4_max) according to the wheel slip (ms) and a driving speed (v), and - c1) actuating a clutch-transmission unit with an engagement process duration (tc) greater than a standard engagement process duration (tcs) provided when the control sequence is deactivated, - c2) while controlling wheel slip (ms) of the driven wheels (4a, 4b) by determining wheel speeds (n4a, n4b) of the driven wheels (4a, 4b) and at least adjusting an output drive torque at the output shaft, - c3) redefining the maximum engine drive torque (M4_max) according to the wheel slip (ms) and a driving speed (v), and d) deactivating the control sequence and resetting the control sequence signal when limit values (μ_tres, v_tres) are reached.
A retraction device for retracting an incision in a body wall, the retraction device comprising: an outer ring having a substantially annular shape with an adjustable circumference, the outer ring being divided into a plurality of curved ring segments, each of the curved ring segments including a first, proximal side, a second, distal side, a first end about the circumference of the outer ring, and a second end about the circumference of the outer ring; and a substantially tubular structure extending distally from the outer ring, the substantially tubular structure being divided into a plurality of elongate tube segments, each of the tube segments being coupled to a respective curved ring segment and extending distally from the respective curved ring segment the retraction device further comprising an inner ring coupled to a distal end of the tubular structure, the inner ring being substantially opposite to the outer ring and having substantially annular shape with an adjustable circumference, the inner ring being divided into a plurality of curved ring segments, each of the curved ring segments including a first, proximal side, a second distal side, a first end about the circumference of the inner ring, and a second end about the circumference of the inner ring; and means for adjusting the circumference of the outer ring and the inner ring, wherein the diameters of the outer ring and the inner ring are increased by moving the curved ring segments further apart and the diameter are decreased by moving the curved ring segments closer together. an outer ring having a substantially annular shape with an adjustable circumference, the outer ring being divided into a plurality of curved ring segments, each of the curved ring segments including a first, proximal side, a second, distal side, a first end about the circumference of the outer ring, and a second end about the circumference of the outer ring; and a substantially tubular structure extending distally from the outer ring, the substantially tubular structure being divided into a plurality of elongate tube segments, each of the tube segments being coupled to a respective curved ring segment and extending distally from the respective curved ring segment the retraction device further comprising an inner ring coupled to a distal end of the tubular structure, the inner ring being substantially opposite to the outer ring and having substantially annular shape with an adjustable circumference, the inner ring being divided into a plurality of curved ring segments, each of the curved ring segments including a first, proximal side, a second distal side, a first end about the circumference of the inner ring, and a second end about the circumference of the inner ring; and means for adjusting the circumference of the outer ring and the inner ring, wherein the diameters of the outer ring and the inner ring are increased by moving the curved ring segments further apart and the diameter are decreased by moving the curved ring segments closer together.
A hair removal device having a housing and an actuator head, which actuator head is arranged movably on the housing and in which a hair-removing actuator system (9, 10) is formed which can be driven by an electric drive unit (11, 79) arranged in the hair removal device, wherein the actuator system (9, 10) can be brought into at least one hair-treating active position and, in order to adjust the actuator head into an active position, said actuator head can be turned by 360° in the housing about an axis of rotation formed within the actuator head, characterized in that the electric drive unit is comprised of a linear motor formed in the actuator head.
A method of manufacturing a planar transformer, the method comprising: forming a first electrically conductive trace (W a P2) of at least one primary winding of the planar transformer on a first circuit layer (L2P2), the first electrically conductive trace having a first termination portion (T in L2) and a second termination portion (T out L2) defining a first gap (GP a L2, GP b L2) therebetween; forming a second electrically conductive trace (W a P1) of at least one primary winding of the planar transformer on a second circuit layer (L3P1), the second electrically conductive trace having a first termination portion (T in L3) and a second termination portion (T out L3) defining a second gap (GP a L3, GP b L3) therebetween; forming a third electrically conductive trace as a grounded portion (GDL4; GDL1) on a third circuit layer (L4S1; L1S1), wherein the third circuit layer includes an electrically conductive trace (W3S1, W4S1; W1S1, W2S1) forming a winding of at least one secondary winding of the planar transformer; stacking the first, second and third circuit layers together in a first direction so that the second gap (GP b L3) is offset from the first gap (GP b L2) in a second direction perpendicular to the first direction and so that the grounded portion is positioned adjacent to the first gap and aligned therewith in the first direction or is positioned adjacent to the second gap and aligned therewith in the first direction. forming a first electrically conductive trace (W a P2) of at least one primary winding of the planar transformer on a first circuit layer (L2P2), the first electrically conductive trace having a first termination portion (T in L2) and a second termination portion (T out L2) defining a first gap (GP a L2, GP b L2) therebetween; forming a second electrically conductive trace (W a P1) of at least one primary winding of the planar transformer on a second circuit layer (L3P1), the second electrically conductive trace having a first termination portion (T in L3) and a second termination portion (T out L3) defining a second gap (GP a L3, GP b L3) therebetween; forming a third electrically conductive trace as a grounded portion (GDL4; GDL1) on a third circuit layer (L4S1; L1S1), wherein the third circuit layer includes an electrically conductive trace (W3S1, W4S1; W1S1, W2S1) forming a winding of at least one secondary winding of the planar transformer; stacking the first, second and third circuit layers together in a first direction so that the second gap (GP b L3) is offset from the first gap (GP b L2) in a second direction perpendicular to the first direction and so that the grounded portion is positioned adjacent to the first gap and aligned therewith in the first direction or is positioned adjacent to the second gap and aligned therewith in the first direction.
A tagger ring foil closure system for a container, such as a can, characterized in that it comprises a composite foil having the following layers: a paper layer having a thickness between 25 and 100gsm, a first polymer layer having a thickness between 10 and 30 um, said first polymer layer comprising a low density polyethylene co-extruded with an acrylic acid such as ethylene acrylic acid, a metal layer having a thickness between 15 and 30 um, the metal of the metal layer comprising aluminium, and a second polymer layer with one of the layers comprising, a filler, the foil having a board burst strength, when measured with Australian Standard 1301.438s, of less than 400 KPa and/or a cross direction ring crush resistance pressure, defined as the ring crush measured using AS 1301.407s, divided by 0.152 and multiplied by the foil thickness measured using AS 1301.426s, of less than 10 MPa. a paper layer having a thickness between 25 and 100gsm, a first polymer layer having a thickness between 10 and 30 um, said first polymer layer comprising a low density polyethylene co-extruded with an acrylic acid such as ethylene acrylic acid, a metal layer having a thickness between 15 and 30 um, the metal of the metal layer comprising aluminium, and a second polymer layer with one of the layers comprising, a filler, the foil having a board burst strength, when measured with Australian Standard 1301.438s, of less than 400 KPa and/or a cross direction ring crush resistance pressure, defined as the ring crush measured using AS 1301.407s, divided by 0.152 and multiplied by the foil thickness measured using AS 1301.426s, of less than 10 MPa.
Flibanserin, optionally in form of the free base, the pharmacologically acceptable acid addition salts and/or optionally in form of the hydrates and/or solvates thereof, for use in the treatment and/or prevention of obesity, promoting, increasing or facilitating weight loss, inhibiting or prevention of body weight gain, and/or inhibiting or reducing appetite.
A patterned apertured web comprising: a plurality of land areas in the patterned apertured web; and a plurality of apertures defined in the patterned apertured web, wherein at least some of the land areas surround at least some of the apertures; wherein the patterned apertured web has an Effective Open Area in the range of 5% to 50%, according to the Aperture Test herein; and wherein the patterned apertured web has a plurality of Interaperture Distances, according to the Aperture Test herein, wherein the Interaperture Distances have a distribution having a median and a mean, and wherein the mean is greater than the median, wherein the mean is greater than the median by at least 8% and less than 20%. a plurality of land areas in the patterned apertured web; and a plurality of apertures defined in the patterned apertured web, wherein at least some of the land areas surround at least some of the apertures; wherein the patterned apertured web has an Effective Open Area in the range of 5% to 50%, according to the Aperture Test herein; and wherein the patterned apertured web has a plurality of Interaperture Distances, according to the Aperture Test herein, wherein the Interaperture Distances have a distribution having a median and a mean, and wherein the mean is greater than the median, wherein the mean is greater than the median by at least 8% and less than 20%.
An electronic component, comprising a substrate (52;) a die bonding pad provided on an upper surface of the substrate and formed in a ring-shape; a semiconductor element having a cavity so that a lower surface of the semiconductor element is formed into a ring-shape so as to surround the cavity; wherein the lower surface of said semiconductor element is bonded onto the ring-shaped die bonding pad by a die bonding resin; characterized in that at least an outer peripheral portion of an upper surface of the ring-shaped die bonding pad is made of an inorganic material, the inorganic material of the outer peripheral portion being exposed, wherein a conductive pattern is provided adjacent to the ring-shaped die bonding pad, the conductive pattern being covered by a coating member, wherein the ring-shaped die bonding pad and the conductive pattern are separated by an air gap and the inorganic material has low wettability to the die bonding resin so that the coating member covering the conductive pattern does not come into contact with the ring-shaped die bonding pad and the die bonding resin does not come into contact with the coating member.
A method for enabling a Call Waiting or Call Back service in an IMS based communications network comprising an originating part and a terminating part, the method comprising the following steps to be executed in an application server in the terminating part: • receiving a request-to-establish message formatted in accordance with SIP, Session Initiation Protocol, from the originating part, the message being initiated by a calling party using a calling communication terminal associated to the originating part, • supplementing the request-to-establish message with information formatted in accordance with SIP, that the Call Waiting or Call Back service is desired to a called party, using a called communication terminal (104, 124) associated to the terminating part, and transmitting the request-to-establish message to an access node via which the called communication terminal is associated, and • receiving a confirmation formatted in accordance with SIP, from the access node that the called communication terminal has been notified regarding that the Call Waiting or Call Back service is applicable. • receiving a request-to-establish message formatted in accordance with SIP, Session Initiation Protocol, from the originating part, the message being initiated by a calling party using a calling communication terminal associated to the originating part, • supplementing the request-to-establish message with information formatted in accordance with SIP, that the Call Waiting or Call Back service is desired to a called party, using a called communication terminal (104, 124) associated to the terminating part, and transmitting the request-to-establish message to an access node via which the called communication terminal is associated, and • receiving a confirmation formatted in accordance with SIP, from the access node that the called communication terminal has been notified regarding that the Call Waiting or Call Back service is applicable.
A wireless communication method (3300, 3500), implemented by a wireless communication device, comprising: determining a maximum delay spread for a transmission channel (3302, 3502); determining a maximum Doppler frequency spread for the transmission channel (3304, 3504); allocating, based on the maximum delay spread and the maximum Doppler frequency spread, a set of transmission resources in a time-frequency domain to a number of pilot signals in the time-frequency domain (3306, 3508); wherein the pilot signals are packed within the set of transmission resources using a delay-Doppler pilot packing, wherein the delay-Doppler pilot packing comprises arranging the pilot signals in a delay-Doppler plane by keeping a distance between the pilot signals in a delay dimension larger than or equal to the maximum delay spread, and keeping a distance between the pilot signals in a Doppler dimension larger than or equal to the maximum Doppler frequency spread; generating the pilot signals by scrambling a basis signal using a two-dimensional, 2-D, chirp sequence; and transmitting, using an orthogonal time frequency space, OTFS, modulation, the pilot signals (3308, 3510) over a wireless communication channel using transmission resources of the set of transmission resources that are designated for pilot signal transmission, wherein each of the pilot signals corresponds to a delta function in a delay-Doppler domain based on applying an inverse symplectic discrete Fourier transform to the pilot signals. determining a maximum delay spread for a transmission channel (3302, 3502); determining a maximum Doppler frequency spread for the transmission channel (3304, 3504); allocating, based on the maximum delay spread and the maximum Doppler frequency spread, a set of transmission resources in a time-frequency domain to a number of pilot signals in the time-frequency domain (3306, 3508); wherein the pilot signals are packed within the set of transmission resources using a delay-Doppler pilot packing, wherein the delay-Doppler pilot packing comprises arranging the pilot signals in a delay-Doppler plane by keeping a distance between the pilot signals in a delay dimension larger than or equal to the maximum delay spread, and keeping a distance between the pilot signals in a Doppler dimension larger than or equal to the maximum Doppler frequency spread; generating the pilot signals by scrambling a basis signal using a two-dimensional, 2-D, chirp sequence; and transmitting, using an orthogonal time frequency space, OTFS, modulation, the pilot signals (3308, 3510) over a wireless communication channel using transmission resources of the set of transmission resources that are designated for pilot signal transmission, wherein each of the pilot signals corresponds to a delta function in a delay-Doppler domain based on applying an inverse symplectic discrete Fourier transform to the pilot signals.
An isolated peptide consisting of: a) a fragment of 3 to 15 amino acids of the sequence defined by amino acids 579 to 601 of SEQ ID NO: 1; b) a fragment of 3 to 15 amino acids of the sequence corresponding to (a) in a non-human mammalian CD31; or c) a fragment of 3 to 15 amino acids consisting of a sequence at least 80% identical to (a), wherein said peptide exerts a dose-dependent inhibition of T-cell proliferation in vitro and does not consist of an amino acid sequence of SEQ ID NO: 5 or 6; d) a peptide as defined in any one of (a)-(c) wherein one or more naturally occurring amino acids (L enantiomer) is replaced with the corresponding D-enantiomer; e) a peptide as defined in any one of (a)-(c) wherein one or more naturally occurring amino acids (L enantiomer) is replaced with the corresponding D-enantiomer, together with an inversion of the amino acid chain. a) a fragment of 3 to 15 amino acids of the sequence defined by amino acids 579 to 601 of SEQ ID NO: 1; b) a fragment of 3 to 15 amino acids of the sequence corresponding to (a) in a non-human mammalian CD31; or c) a fragment of 3 to 15 amino acids consisting of a sequence at least 80% identical to (a), wherein said peptide exerts a dose-dependent inhibition of T-cell proliferation in vitro and does not consist of an amino acid sequence of SEQ ID NO: 5 or 6; d) a peptide as defined in any one of (a)-(c) wherein one or more naturally occurring amino acids (L enantiomer) is replaced with the corresponding D-enantiomer; e) a peptide as defined in any one of (a)-(c) wherein one or more naturally occurring amino acids (L enantiomer) is replaced with the corresponding D-enantiomer, together with an inversion of the amino acid chain.
Connection between a first metallic component and a second metallic component wrapped by a sheath (1.2), which second metallic component forms a conductor (1.1), the first and the second metallic component (2, 1) being connected to one another by a welded connection and respectively a section of the first metallic component and an at least one section of the sheath (1.2) comprising part of the second metallic component are surrounded by an applied insulating material layer, and wherein the insulating material layer is encapsulated and meshed by the action of heat to the sheath (1.2) so that the welding point is surrounded by a sheath made of the insulating material, the first metallic component being a cable lug and having a receiving region surrounding the conductor (1.1) through which the conductor (1.1) extends, characterized in that the sheath (1.2) consists of a polyorganosiloxane, namely HTV silicone, and the applied insulating material layer consists of a polyorganosiloxane, namely liquid silicone, wherein, for surface activation, a connecting region between the cable lug and the conductor (1.1) and the part of the sheath (1.2) to be encapsulated were exposed to an insulated atmospheric plasma before the encapsulation and subsequently meshed at a temperature of approximately 160°C to approximately 210°C.