A compound of general formula wherein Q 1 to Q 5 identical or different represent CR 6, R 1 represents C 6 -C 10 aryl comprising one or two fused rings, wherein from 2 to 5 carbon atoms may be replaced with a heteroatom selected from O, S, N and NR 6, and eventually substituted with from 5 to 11 substituents selected from R 6, halo, CN, NO 2, CF 3, OCF 3, COOR 6, OCOR 6, SO 2 NR 6 R 7, CONR 6 R 7, NR 6 R 7, NR 6 COR 7, (CH 2) p - NR 6 R 7, (CH 2) p - OR 6 and (CH 2) p SR 6, R 2 is SO 2 R 1 or R 6 R 3 and R 4 identical or different are selected from COR 8 and R 6 R 5 represents R 6, aryl, OR 6, SR 6, halo, CN, NO 2, CF 3, OCF 3, COOR 6, SO 2 NR 6 R 7, CONR 6 R 7, NR 6 R 7 and NHCOR 6, R 6 and R 7 identical or different represent H or alkyl R 8 is selected from H, alkyl, cycloalkyl, aryl, alkylaryl, wherein aryl may be substituted with from one to four R 5 substituents identical or different, or R 8 represents -(CH 2) q -NR 6 R 7, p represents an integer from 0 to 6, q represents an integer from 0 to 6, wherein the thiazolyl group is linked to the 6 member group in meta or para position with respect to the sulfonamide group and wherein the thiazolyl group is linked to the 6-member group in position α or β with respect to the S atom, with the exclusion of the following compounds: N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-2-hydroxybenzamide, 2-(acetyloxy)-N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-benzamide, 3-chloro-N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-benzamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-1-hydroxy-2-naphtalenecarboxamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-3-hydroxy-2-naphtalenecarboxamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-2-methoxybenzamide, N-[3-(2-amino-4-thiazolyl) phenyl]-4-chloro-benzenesulfonamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-benzamide, 2-chloro-N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-benzamide, 4-chloro-N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-benzamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-3,4-dimethoxy benzamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-3-methoxy benzamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-4-methoxy benzamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-3-methyl-benzamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-4-methyl-benzamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-4-nitro-benzamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-4-methyl-benzamide, or, if appropriate, their pharmaceutically acceptable salts and/or tautomers, solvates or isotopic variations thereof. Q 1 to Q 5 identical or different represent CR 6, R 1 represents C 6 -C 10 aryl comprising one or two fused rings, wherein from 2 to 5 carbon atoms may be replaced with a heteroatom selected from O, S, N and NR 6, and eventually substituted with from 5 to 11 substituents selected from R 6, halo, CN, NO 2, CF 3, OCF 3, COOR 6, OCOR 6, SO 2 NR 6 R 7, CONR 6 R 7, NR 6 R 7, NR 6 COR 7, (CH 2) p - NR 6 R 7, (CH 2) p - OR 6 and (CH 2) p SR 6, R 2 is SO 2 R 1 or R 6 R 3 and R 4 identical or different are selected from COR 8 and R 6 R 5 represents R 6, aryl, OR 6, SR 6, halo, CN, NO 2, CF 3, OCF 3, COOR 6, SO 2 NR 6 R 7, CONR 6 R 7, NR 6 R 7 and NHCOR 6, R 6 and R 7 identical or different represent H or alkyl R 8 is selected from H, alkyl, cycloalkyl, aryl, alkylaryl, wherein aryl may be substituted with from one to four R 5 substituents identical or different, or R 8 represents -(CH 2) q -NR 6 R 7, p represents an integer from 0 to 6, q represents an integer from 0 to 6, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-2-hydroxybenzamide, 2-(acetyloxy)-N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-benzamide, 3-chloro-N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-benzamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-1-hydroxy-2-naphtalenecarboxamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-3-hydroxy-2-naphtalenecarboxamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-2-methoxybenzamide, N-[3-(2-amino-4-thiazolyl) phenyl]-4-chloro-benzenesulfonamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-benzamide, 2-chloro-N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-benzamide, 4-chloro-N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-benzamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-3,4-dimethoxy benzamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-3-methoxy benzamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-4-methoxy benzamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-3-methyl-benzamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-4-methyl-benzamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-4-nitro-benzamide, N-[4-[3-[[(4-chlorophenyl) sulfonyl] amino] phenyl]-2-thiazolyl]-4-methyl-benzamide,