A lacrimal drainage manometer comprising: a syringe including a syringe body and a piston, said syringe body defining a fluid cavity, said syringe body having one or more grooves configured in a spiral pattern about an inner surface of a docking portion, said piston for dispensing a fluid from said fluid cavity through a cannula, said cannula being configured for insertion into at least a portion of a lacrimal drainage system; a detachable member of the syringe, said detachable member having a spiral-shaped edge configured to mate with said spiral shaped patterned grooves of said docking portion, said cannula being integrally formed with said detachable member, said detachable member having a lumen extending therethrough, said lumen being in fluid communication with said fluid cavity and said cannula; a pressure sensor operably coupled to said syringe and being configured to detect pressure in said fluid cavity; a fluid flow sensor coupled to said syringe, said fluid flow sensor operably attached to said detachable member, said fluid flow sensor integrated into a portion of a wall defining the lumen or directly attached to a wall that defines the lumen and said fluid flow sensor configured to measure the flow rate of fluid through said syringe; and a user feedback unit in electrical communication with each of said pressure sensor and said fluid flow sensor, said user feedback unit being directly connected to said syringe and configured to provide user feedback based on data from said pressure sensor and/or said fluid flow sensor, wherein said user feedback unit comprises a housing having an integrated display for providing said data to a user; wherein said housing is directly attached to a first end of said syringe body, and said housing is serially reusable with different syringes and the respective syringe is single-use disposable, wherein said user feedback unit is configured to calculate and display a resistance value on said integrated display when the contents of said fluid cavity are expelled from said lacrimal drainage manometer. a syringe including a syringe body and a piston, said syringe body defining a fluid cavity, said syringe body having one or more grooves configured in a spiral pattern about an inner surface of a docking portion, said piston for dispensing a fluid from said fluid cavity through a cannula, said cannula being configured for insertion into at least a portion of a lacrimal drainage system; a detachable member of the syringe, said detachable member having a spiral-shaped edge configured to mate with said spiral shaped patterned grooves of said docking portion, said cannula being integrally formed with said detachable member, said detachable member having a lumen extending therethrough, said lumen being in fluid communication with said fluid cavity and said cannula; a pressure sensor operably coupled to said syringe and being configured to detect pressure in said fluid cavity; a fluid flow sensor coupled to said syringe, said fluid flow sensor operably attached to said detachable member, said fluid flow sensor integrated into a portion of a wall defining the lumen or directly attached to a wall that defines the lumen and said fluid flow sensor configured to measure the flow rate of fluid through said syringe; and a user feedback unit in electrical communication with each of said pressure sensor and said fluid flow sensor, said user feedback unit being directly connected to said syringe and configured to provide user feedback based on data from said pressure sensor and/or said fluid flow sensor, wherein said user feedback unit comprises a housing having an integrated display for providing said data to a user; wherein said housing is directly attached to a first end of said syringe body, and said housing is serially reusable with different syringes and the respective syringe is single-use disposable, wherein said user feedback unit is configured to calculate and display a resistance value on said integrated display when the contents of said fluid cavity are expelled from said lacrimal drainage manometer.