A 5,6- or 6,7-epoxy-tigliane compound or a pharmaceutically acceptable salt thereof for use in promoting wound healing; wherein the 5,6- or 6,7-epoxy-tigliane compound is a compound of formula: wherein R 1 is hydrogen and R 2 is -OR 17; or R 1 and R 2 together form a carbonyl group (=O); R 3 is hydrogen or C 1-6 alkyl; R 4 and R 5 are independently hydrogen or -OR 17; or R 4 and R 5 together form a double bond or an epoxide (-O-); R 6 is hydrogen or C 1-6 alkyl; R 7 is -OH or -OR 18; R 8 is -OH or -OR 18; provided that R 7 and R 8 are not both OH; R 9 and R 10 are independently selected from hydrogen and C 1-6 alkyl; R 11 and R 12 or R 12 and R 13 together form an epoxide and the remaining group of R 11 and R 13 is hydrogen, -OH or -OR 17 R 14 is hydrogen or -R 17; R 15 is hydrogen or -R 17; R 16 is hydrogen or -R 17; R 17 is hydrogen, -C 1-6 alkyl, -C 2-6 alkenyl, -C 2-6 alkynyl, -C C 1-6 alkyl, -C C 2-6 alkenyl or -C C 2-6 alkynyl; R 18 is C 1-20 alkyl, -C 2-20 alkenyl, -C 2-20 alkynyl, -C C 1-20 alkyl, -C C 2-20 alkenyl, -C C 2-20 alkynyl, -C cycloalkyl, -C C 1-10 alkylcycloalkyl; -C C 2-10 alkenylcycloalkyl, -C C 2-10 alkynylcycloalkyl, -C aryl, -C C 1-10 alkylaryl, -C C 2-10 alkenylaryl, -C C 2-10 alkynylaryl, -C C 1-10 alkylC R 19, -C C 2-10 alkenylC R 19, -C C 2-10 alkynylC R 19, -C C 1-10 alkylCH(OR 19)(OR 19), -C C 2-10 alkenylCH(OR 19)(OR 19), -C C 2-10 alkynylCH(OR 19)(OR 19), -C C 1-10 alkylSR 19, -C C 2-10 alkenylSR 19, -C C 2-10 alkynylSR 19, -C C 1-10 alkylC OR 19, -C C 2-10 alkenylC OR 19, -C C 2-10 alkynylC OR 19, -C C 1-10 alkylC SR 19, -C C 2-10 alkenylC SR 19, -C C 2-10 alkynylC SR 19, or and R 19 is hydrogen, -C 1-10 alkyl, -C 2-10 alkenyl, -C 2-10 alkynyl, cycloalkyl or aryl; wherein each alkyl, alkenyl, alkynyl, cycloalkyl or aryl group is optionally substituted; or a geometric isomer or stereoisomer or a pharmaceutically acceptable salt thereof. R 1 is hydrogen and R 2 is -OR 17; or R 1 and R 2 together form a carbonyl group (=O); R 3 is hydrogen or C 1-6 alkyl; R 4 and R 5 are independently hydrogen or -OR 17; or R 4 and R 5 together form a double bond or an epoxide (-O-); R 6 is hydrogen or C 1-6 alkyl; R 7 is -OH or -OR 18; R 8 is -OH or -OR 18; provided that R 7 and R 8 are not both OH; R 9 and R 10 are independently selected from hydrogen and C 1-6 alkyl; R 11 and R 12 or R 12 and R 13 together form an epoxide and the remaining group of R 11 and R 13 is hydrogen, -OH or -OR 17 R 14 is hydrogen or -R 17; R 15 is hydrogen or -R 17; R 16 is hydrogen or -R 17; R 17 is hydrogen, -C 1-6 alkyl, -C 2-6 alkenyl, -C 2-6 alkynyl, -C C 1-6 alkyl, -C C 2-6 alkenyl or -C C 2-6 alkynyl; R 18 is C 1-20 alkyl, -C 2-20 alkenyl, -C 2-20 alkynyl, -C C 1-20 alkyl, -C C 2-20 alkenyl, -C C 2-20 alkynyl, -C cycloalkyl, -C C 1-10 alkylcycloalkyl; -C C 2-10 alkenylcycloalkyl, -C C 2-10 alkynylcycloalkyl, -C aryl, -C C 1-10 alkylaryl, -C C 2-10 alkenylaryl, -C C 2-10 alkynylaryl, -C C 1-10 alkylC R 19, -C C 2-10 alkenylC R 19, -C C 2-10 alkynylC R 19, -C C 1-10 alkylCH(OR 19)(OR 19), -C C 2-10 alkenylCH(OR 19)(OR 19), -C C 2-10 alkynylCH(OR 19)(OR 19), -C C 1-10 alkylSR 19, -C C 2-10 alkenylSR 19, -C C 2-10 alkynylSR 19, -C C 1-10 alkylC OR 19, -C C 2-10 alkenylC OR 19, -C C 2-10 alkynylC OR 19, -C C 1-10 alkylC SR 19, -C C 2-10 alkenylC SR 19, -C C 2-10 alkynylC SR 19, or and R 19 is hydrogen, -C 1-10 alkyl, -C 2-10 alkenyl, -C 2-10 alkynyl, cycloalkyl or aryl; wherein each alkyl, alkenyl, alkynyl, cycloalkyl or aryl group is optionally substituted; or a geometric isomer or stereoisomer or a pharmaceutically acceptable salt thereof.