A compound represented by the following Formula 1 or a pharmaceutically-acceptable salt thereof: wherein: R 1 and R 2 are C 1-3 alkyl, or R 1 and R 2 jointly form a pyrrolidine, 3-fluoropyrrolidine, 3,3-difluoropyrrolidine, 3-hydroxypyrcolidine, morpholine, thiomorpholine, piperazine, C 1-6 alkyl-piperazine, azetidine, tetrahydrothiazole, indoline or 2H-pyrrole group; each R 3 is independently selected from H, C 1-20 alkyl, C 3-6 cycloalkyl, aryl-C 1-4 alkyl, aryl-(hydroxy)C 1-4 alkyl, COR 7 and CO 2 R 7, the aryl groups optionally being substituted witch 1-3 groups independently selected from halogen, C 1-6 alkyl, C 1-6 alkoxy and C, _ 3 thioxy; R 7 is H, C 1-20 alkyl, aryl or aryl-C 1-4 alkyl, the C 1-20 alkyl group optionally being substituted with NH 2, and the aryl groups optionally being substituted with 1-3 groups independently selected from halogen, C 1-6 alkyl, C 1-6 alkoxy and C 1-3 thioxy; R 4 is H or COR 8; R 8 is C 1-6 alkyl; the wavy lines represent bonds connected to carbons having an R or S configuration; the dashed lines represent optional bonds, with the proviso that the ring containing the dashed lines is aromatic; m, n and q are integers independently selected from 0, 1, 2 and 3, with the proviso that the sum of m, n and q is 2 or 3; s is zero, except when X is N, in which case s is 0 or 1; W, X and Y independently represent CH, CR 5, CR 6 or a heteroatom selected from N, O and S, with the proviso that when the sum of m, n and q is 2, one or two of W, X and Y is a heteroatom, and when the sum of m, n and q is 3, none or one of W, X and Y is a heteroatom; and R 5 and R 6 are independently selected from H, halogen and C 1-6 alkyl, or R 5 and R 6, together with the atoms to which they are attached, jointly form a carbocyclic or heterocyclic ring having 5 or 6 atoms in the ring, 1-3 atoms in the heterocyclic ring being independently selected from N, O and S; with the proviso that Formula 1 does not cover compounds where R 4 is H, R 1 and R 2 jointly with the nitrogen atom form a pyrrolidine or morpholine ring, the sum of m, n and q is 3, and none of W, X and Y represents a heteroatom. R 1 and R 2 are C 1-3 alkyl, or R 1 and R 2 jointly form a pyrrolidine, 3-fluoropyrrolidine, 3,3-difluoropyrrolidine, 3-hydroxypyrcolidine, morpholine, thiomorpholine, piperazine, C 1-6 alkyl-piperazine, azetidine, tetrahydrothiazole, indoline or 2H-pyrrole group; each R 3 is independently selected from H, C 1-20 alkyl, C 3-6 cycloalkyl, aryl-C 1-4 alkyl, aryl-(hydroxy)C 1-4 alkyl, COR 7 and CO 2 R 7, the aryl groups optionally being substituted witch 1-3 groups independently selected from halogen, C 1-6 alkyl, C 1-6 alkoxy and C, _ 3 thioxy; R 7 is H, C 1-20 alkyl, aryl or aryl-C 1-4 alkyl, the C 1-20 alkyl group optionally being substituted with NH 2, and the aryl groups optionally being substituted with 1-3 groups independently selected from halogen, C 1-6 alkyl, C 1-6 alkoxy and C 1-3 thioxy; R 4 is H or COR 8; R 8 is C 1-6 alkyl; the wavy lines represent bonds connected to carbons having an R or S configuration; the dashed lines represent optional bonds, with the proviso that the ring containing the dashed lines is aromatic; m, n and q are integers independently selected from 0, 1, 2 and 3, with the proviso that the sum of m, n and q is 2 or 3; s is zero, except when X is N, in which case s is 0 or 1; W, X and Y independently represent CH, CR 5, CR 6 or a heteroatom selected from N, O and S, with the proviso that when the sum of m, n and q is 2, one or two of W, X and Y is a heteroatom, and when the sum of m, n and q is 3, none or one of W, X and Y is a heteroatom; and R 5 and R 6 are independently selected from H, halogen and C 1-6 alkyl, or R 5 and R 6, together with the atoms to which they are attached, jointly form a carbocyclic or heterocyclic ring having 5 or 6 atoms in the ring, 1-3 atoms in the heterocyclic ring being independently selected from N, O and S; with the proviso that Formula 1 does not cover compounds where R 4 is H, R 1 and R 2 jointly with the nitrogen atom form a pyrrolidine or morpholine ring, the sum of m, n and q is 3, and none of W, X and Y represents a heteroatom.