mhurhangee/ep-ind-claims huggingface dataset:
Autonomous vehicle comprising a frame with - a propulsion system (5, 6) for displacing said vehicle, - a bumper that is connected to said frame via at least one connecting device, and is elastically displaceable around a rest position, - a sensor (11, 11') for detecting displacement of said bumper with respect to the frame upon collision with an object, wherein the sensor (11, 11') is operably connected with said propulsion system (5, 6), wherein said propulsion system (5, 6) is arranged to interrupt displacing said vehicle if the sensor (11, 11') detects a displacement, characterised in that at least one, and preferably each, connecting device comprises: - a ring, - a first ball part, - a second ball part, - a shaft with a first end and a second end, - a spring means, wherein the ring is fixedly connected to the frame, wherein the first ball part and the second ball part are both provided rotatably tiltable with respect to the ring on opposite sides thereof, wherein the shaft has an abutment means for the first ball part towards or at the first end, and extends through the ring and the first ball part, and extends through and beyond the second ball part to the second, distal end, at or near which the shaft is connected to said bumper by means of a joint, wherein at least one of the first and second ball parts (14, 15) is displaceable along the shaft, wherein the spring means is connected to, or presses against, a spring connector which is fixedly connected to the shaft at or near a first end thereof, wherein the spring means extends around or along the shaft between the second ball part and the spring connector, and is arranged to pretensionedly press the first and second ball parts (14, 15) against the ring. - a propulsion system (5, 6) for displacing said vehicle, - a bumper that is connected to said frame via at least one connecting device, and is elastically displaceable around a rest position, - a sensor (11, 11') for detecting displacement of said bumper with respect to the frame upon collision with an object, - a ring, - a first ball part, - a second ball part, - a shaft with a first end and a second end, - a spring means,
A circuit for processing Carrier Aggregation, characterized by comprising: a plurality of Component Carrier processors, each CC processor configured to estimate a frequency offset for a related CC and to compensate the estimated frequency offset; a reference clock generator configured to generate a reference clock using a reference frequency offset as one of frequency offsets output from the plurality of CC processors; a plurality of reception Phase Lock Loop units, each reception PLL unit configured to generate a reception carrier frequency for the related CC corresponding to the reference clock; and a plurality of transmission PLL units, each transmission PLL unit configured to generate a transmission carrier frequency for the related CC corresponding to the reference clock. a plurality of Component Carrier processors, each CC processor configured to estimate a frequency offset for a related CC and to compensate the estimated frequency offset; a reference clock generator configured to generate a reference clock using a reference frequency offset as one of frequency offsets output from the plurality of CC processors; a plurality of reception Phase Lock Loop units, each reception PLL unit configured to generate a reception carrier frequency for the related CC corresponding to the reference clock; and a plurality of transmission PLL units, each transmission PLL unit configured to generate a transmission carrier frequency for the related CC corresponding to the reference clock.
An apparatus for bone cement delivery comprising: a proximal nozzle portion having a proximal end configured to couple to a bone cement source and a first distal delivery end having a circular cross section; a distal nozzle augment having a proximal end configured to slideably couple to the first distal delivery end and a second distal delivery end having an oblong cross section, wherein the distal nozzle augment includes a longitudinal axis and the second distal delivery end includes a slanted face disposed at an acute angle between 20 °and 35 ° relative to the longitudinal axis to allow the slanted face to make substantially parallel contact with a delivery surface; wherein the slanted face tapers relative to the second distal delivery end to provide a funnel embedded in the distal nozzle augment; and an attachment mechanism configured to slideably retain the distal nozzle augment to the proximal nozzle portion. a proximal nozzle portion having a proximal end configured to couple to a bone cement source and a first distal delivery end having a circular cross section; a distal nozzle augment having a proximal end configured to slideably couple to the first distal delivery end and a second distal delivery end having an oblong cross section, wherein the distal nozzle augment includes a longitudinal axis and the second distal delivery end includes a slanted face disposed at an acute angle between 20 °and 35 ° relative to the longitudinal axis to allow the slanted face to make substantially parallel contact with a delivery surface; wherein the slanted face tapers relative to the second distal delivery end to provide a funnel embedded in the distal nozzle augment; and an attachment mechanism configured to slideably retain the distal nozzle augment to the proximal nozzle portion.
A coaxial fuel and oxygen pipe apparatus, comprising: a fuel pipe and an oxygen pipe, wherein the fuel pipe is contained within the oxygen pipe and the oxygen pipe comprises an internal diameter that is continuous without diameter changes along a length of the oxygen pipe, and wherein the fuel pipe comprises an internal diameter that is continuous without diameter variations along a length of the fuel pipe; and a discharge block having a diverging section and a discharge that forms a final outlet with respect to the fuel pipe and the oxygen pipe, wherein the discharge block is configured with two angles that facilitate conditions for eliminating recirculation, and wherein the two angles are matched to an expansion rate of the products of combustion to maintain a positive pressure throughout a final discharge from the final outlet; and a burner inserted into the discharge block, wherein oxygen enters the oxygen pipe in a hole through the burner at a right angle to a longitudinal axis of the burner and fuel enters the fuel pipe axially through the burner, wherein the fuel pipe extends beyond the oxygen pipe, the fuel pipe includes a first fuel pipe portion and a second fuel pipe portion, and wherein the second fuel pipe portion is thinner and narrower than the first fuel pipe portion. a fuel pipe and an oxygen pipe, wherein the fuel pipe is contained within the oxygen pipe and the oxygen pipe comprises an internal diameter that is continuous without diameter changes along a length of the oxygen pipe, and wherein the fuel pipe comprises an internal diameter that is continuous without diameter variations along a length of the fuel pipe; and a discharge block having a diverging section and a discharge that forms a final outlet with respect to the fuel pipe and the oxygen pipe, wherein the discharge block is configured with two angles that facilitate conditions for eliminating recirculation, and wherein the two angles are matched to an expansion rate of the products of combustion to maintain a positive pressure throughout a final discharge from the final outlet; and a burner inserted into the discharge block, wherein oxygen enters the oxygen pipe in a hole through the burner at a right angle to a longitudinal axis of the burner and fuel enters the fuel pipe axially through the burner, wherein the fuel pipe extends beyond the oxygen pipe, the fuel pipe includes a first fuel pipe portion and a second fuel pipe portion, and wherein the second fuel pipe portion is thinner and narrower than the first fuel pipe portion.
A process for purifying 1-(6,7-dihydro-5 H -benzo[6,7]cyclohepta[1,2-c]pyridazine-3-yl)- N 3 -(7-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-5 H -benzo annulene-2-yl)-1 H -1,2,4-triazole-3,5-diamine free base, the process comprising a) dissolving a quantity of crude 1-(6,7-dihydro-5 H -benzo[6,7]cyclohepta[1,2-c]pyridazine-3-yl)- N 3 -(7-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-5 H -benzo annulene-2-yl)-1 H -1,2,4-triazole-3,5-diamine in a mixed solvent of C 1-5 alcohol and water, together with an acid, and b) increasing the pH of the solution resulting from (a) until 1-(6,7-dihydro-5 H- benzo[6,7]cyclohepta[1,2-c]pyridazine-3-yl)- N 3 -(7-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-5 H- benzo annulene-2-yl)-1 H -1,2,4-triazole-3,5-diamine free base is precipitated from the alcohol-water mixed solvent. a) dissolving a quantity of crude 1-(6,7-dihydro-5 H -benzo[6,7]cyclohepta[1,2-c]pyridazine-3-yl)- N 3 -(7-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-5 H -benzo annulene-2-yl)-1 H -1,2,4-triazole-3,5-diamine in a mixed solvent of C 1-5 alcohol and water, together with an acid, and b) increasing the pH of the solution resulting from (a) until 1-(6,7-dihydro-5 H- benzo[6,7]cyclohepta[1,2-c]pyridazine-3-yl)- N 3 -(7-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-5 H- benzo annulene-2-yl)-1 H -1,2,4-triazole-3,5-diamine free base is precipitated from the alcohol-water mixed solvent.
Nanoparticle system comprising polymeric nanoparticles consisting of a synthetic polymer, bonded to a heterocarbon chain by covalent bonds between the functional groups present on the polymer and the functional groups present on said heterocarbon chain, a hyaluronidase and one or more active molecules covalently bonded to said heterocarbon chain; wherein: the nanoparticles have a size ranging from 100 to 500 nm; the synthetic polymer is polystyrene; the heterocarbon chain is selected from polyethylene glycol chains; and the active molecules are selected from doxorubicin, fluorophores and antibodies. the nanoparticles have a size ranging from 100 to 500 nm; the synthetic polymer is polystyrene; the heterocarbon chain is selected from polyethylene glycol chains; and the active molecules are selected from doxorubicin, fluorophores and antibodies.
Housing system, which comprises at least two housing parts, each having an associated housing cover, wherein each of the housing parts is of trough-shaped form, whereby the housing part and the associated housing cover each enclose an inner space, and formations and formations complementary to the formations are formed on each housing part, wherein each two housing parts are detachably connected to one another mechanically and/or electrically, preferably in a form-locking and/or force-locking manner, by means of the formations of one of the two housing parts and the complementary formations of the other of the two housing parts, wherein each two housing parts are detachably connected electrically and/or mechanically via a device for electrical connection which is implemented as a plug-in module having a first and second plug-in connector part, wherein the housing part or housing parts are of cuboid shape and the housing parts have a bottom and a first side wall and a second side wall opposite the first side wall, and also a front side connecting the first and second side wall and a corresponding rear side opposite the front side, wherein as a first type of complementary formations laterally projecting engagement elements are formed on the bottom edge of the first side wall and the associated first type of formations are formed as notches open from the bottom on the bottom edge of the second side wall, wherein the front side and the rear side each have a hook element in a bottom corner region facing the first side wall, which hook element protrudes beyond the first side wall, and in a bottom corner region associated with the second side wall a pin element projecting vertically on the front side and the rear side, respectively, wherein in the assembled state of the plurality of housing parts the hook element engages in the respectively associated pin element of the adjacent housing part, wherein cooling elements are integrally formed on the bottom, wherein the cooling elements lie outside the inner space, wherein the cooling elements are formed as cooling ribs arranged parallel to the side walls (124, 126), wherein the engagement elements and the notches are arranged in freestanding end regions of the respective cooling ribs which are implemented as an extension of the first and second side wall, so that the first and second side wall (124,126) is extended beyond the bottom each as one of the cooling ribs.
A system for ablating undesirable soft tissue using radio frequency electrical membrane breakdown, RFEMB, comprising; a bi-polar electric pulse generator configured to produce bi-polar pulses, wherein the bi-polar pulses are characterized by an instant charge reversal between a positive and a negative polarity, at least one therapeutic probe, said probe being an electrode operatively connected to said bi-polar pulse generator, said probe and bi-polar pulse generator configured to apply to said soft tissue the bi-polar pulses to generate an oscillating electric field comprising a field strength in the range of 1500 V/cm to 10,000 V/cm, wherein the oscillating electric field is sufficient to cause RFEMB of a cell membrane of a plurality of cells of said soft tissue wherein RFEMB causes destruction of the cell membrane, immediate spillage of all intracellular components into an extracellular space and exposure of an internal constituent part of said cell membrane to said extracellular space; a temperature probe; and a controller operatively connected to said electric bi-polar pulse generator, said therapeutic probe and said temperature probe. a bi-polar electric pulse generator configured to produce bi-polar pulses, wherein the bi-polar pulses are characterized by an instant charge reversal between a positive and a negative polarity, at least one therapeutic probe, said probe being an electrode operatively connected to said bi-polar pulse generator, said probe and bi-polar pulse generator configured to apply to said soft tissue the bi-polar pulses to generate an oscillating electric field comprising a field strength in the range of 1500 V/cm to 10,000 V/cm, wherein the oscillating electric field is sufficient to cause RFEMB of a cell membrane of a plurality of cells of said soft tissue wherein RFEMB causes destruction of the cell membrane, immediate spillage of all intracellular components into an extracellular space and exposure of an internal constituent part of said cell membrane to said extracellular space; a temperature probe; and a controller operatively connected to said electric bi-polar pulse generator, said therapeutic probe and said temperature probe.
An optical effect layer comprising a plurality of non-spherical magnetic or magnetizable particles, wherein at least a part of the plurality of non-spherical magnetic or magnetizable particles is constituted by non-spherical optically variable magnetic or magnetizable pigments, and wherein the non-spherical magnetic or magnetizable particles are dispersed in a coating composition comprising a binder material, the OEL comprising two or more loop-shaped areas, being nested around a common central area that is surrounded by the innermost loop-shaped area, wherein, in each of the loop-shaped areas, at least a part of the plurality of non-spherical magnetic or magnetizable particles are oriented such that, in a cross-section perpendicular to the OEL layer and extending from the centre of the central area to the outer boundary of the outermost loop-shaped area, the longest axis of the particles in each of the cross-sectional areas of the looped-shaped areas follow a tangent of either a negatively curved or a positively curved part of hypothetical ellipses or circles, and wherein the central area surrounded by the innermost loop-shaped area comprises a plurality of non-spherical magnetic or magnetizable particles, wherein a part of the plurality of non-spherical magnetic or magnetizable particles within the central area are oriented such that their longest axis is substantially parallel to the plane of the OEL, forming the optical effect of a protrusion, characterized in that the optically variable magnetic or magnetizable pigments are selected from the group consisting of magnetic thin-film interference pigments, magnetic cholesteric liquid crystal pigments and mixtures thereof. the OEL comprising two or more loop-shaped areas, being nested around a common central area that is surrounded by the innermost loop-shaped area, wherein, in each of the loop-shaped areas, at least a part of the plurality of non-spherical magnetic or magnetizable particles are oriented such that, in a cross-section perpendicular to the OEL layer and extending from the centre of the central area to the outer boundary of the outermost loop-shaped area, the longest axis of the particles in each of the cross-sectional areas of the looped-shaped areas follow a tangent of either a negatively curved or a positively curved part of hypothetical ellipses or circles, and wherein the central area surrounded by the innermost loop-shaped area comprises a plurality of non-spherical magnetic or magnetizable particles, wherein a part of the plurality of non-spherical magnetic or magnetizable particles within the central area are oriented such that their longest axis is substantially parallel to the plane of the OEL, forming the optical effect of a protrusion, characterized in that the optically variable magnetic or magnetizable pigments are selected from the group consisting of magnetic thin-film interference pigments, magnetic cholesteric liquid crystal pigments and mixtures thereof.
Method for transmitting data via a communications channel, in which the data are transmitted with a transmissions frame, wherein the transmissions frame has at least one prioritization field for determining the priority of the message and a data field, wherein the prioritization field serves to regulate bus access by prioritizing the messages, characterized in that a bus access controller is used in which the priority of at least the last-received data packet is stored in a minimum-priorities storage cell, wherein, after reception of a packet, a timer is started for which at least one time-out value is set and which is reset again when a following packet is received, and wherein, after the time-out value is reached, the value stored in the minimum-priorities storage cell is decremented, and wherein, for bus access control when a packet is transmitted, a check is made as to whether the priority of the packet to be transmitted is lower than the value stored in the minimum-priorities storage cell, and transmission of the packet is prevented if the priority of the packet is lower than the value stored in the minimum-priorities storage cell.
Holding device for a syringe pump, the holding device being configured for holding the barrel of a syringe and comprising: - a rotatable holding member which is rotatable from an open into a closed position, - wherein the holding member is configured in such a way that in the closed position the syringe barrel will be secured between a portion of the rotatable holding member and a fixed section of the syringe pump, a spring configured to bias the holding member against the syringe barrel, wherein the spring is a coil spring surrounding a shaft connected to the holding member, characterized by a damping device configured to dampen a rotation of the rotatable holding member from the open into the closed position. - a rotatable holding member which is rotatable from an open into a closed position, - wherein the holding member is configured in such a way that in the closed position the syringe barrel will be secured between a portion of the rotatable holding member and a fixed section of the syringe pump,
A method of identifying whether a nucleotide is a nucleotide comprising a base complementary to the next base of a template strand immediately downstream of a primer in a primed template nucleic acid molecule, said method comprising: (a) providing the primed template nucleic acid molecule; (b) contacting the primed template nucleic acid molecule with a first reaction mixture that comprises a polymerase and a plurality of different nucleotide molecules, whereby a stabilized ternary complex forms, said stabilized ternary complex comprising one of the plurality of different nucleotide molecules; (c) contacting the primed template nucleic acid molecule, after step (b), with a second reaction mixture that comprises at least one of the different nucleotide molecules and that does not comprise a first nucleotide molecule of the plurality of different nucleotide molecules; (d) monitoring interaction of the polymerase and the primed template nucleic acid molecule in the second reaction mixture, without incorporating any nucleotide into the primer, to detect any of the stabilized ternary complex remaining after step (c); and (e) determining either that: (i) the first nucleotide molecule comprises the base complementary to the next base of the template strand if the stabilized ternary complex dissociates in step (d); or (ii) the first nucleotide molecule does not comprises the base complementary to the next base of the template strand if the stabilized ternary complex is retained in step (d). (a) providing the primed template nucleic acid molecule; (b) contacting the primed template nucleic acid molecule with a first reaction mixture that comprises a polymerase and a plurality of different nucleotide molecules, whereby a stabilized ternary complex forms, said stabilized ternary complex comprising one of the plurality of different nucleotide molecules; (c) contacting the primed template nucleic acid molecule, after step (b), with a second reaction mixture that comprises at least one of the different nucleotide molecules and that does not comprise a first nucleotide molecule of the plurality of different nucleotide molecules; (d) monitoring interaction of the polymerase and the primed template nucleic acid molecule in the second reaction mixture, without incorporating any nucleotide into the primer, to detect any of the stabilized ternary complex remaining after step (c); and (e) determining either that: (i) the first nucleotide molecule comprises the base complementary to the next base of the template strand if the stabilized ternary complex dissociates in step (d); or (ii) the first nucleotide molecule does not comprises the base complementary to the next base of the template strand if the stabilized ternary complex is retained in step (d). (i) the first nucleotide molecule comprises the base complementary to the next base of the template strand if the stabilized ternary complex dissociates in step (d); or (ii) the first nucleotide molecule does not comprises the base complementary to the next base of the template strand if the stabilized ternary complex is retained in step (d).