mhurhangee/ep-ind-claims huggingface dataset:
A method of detecting optical subsystem failures, wherein the optical subsystem has a plurality of optical components that includes receiver optics, transmitter optics, photodetectors (110,112,114) and an external window, the method comprising: emitting a pulsed light beam from a laser through the external window towards a cloud; receiving a plurality of reflection signals, wherein the plurality of reflection signals includes a pair of reflection signals (150b,150c), received at a photodetector measuring reflection off of the external window and at a receiver photodetector, indicative of a portion of the beam reflected by the external window and a reflection signal, received at a trigger photodiode, indicative of portion of the beam reflected by transmitter optics; comparing the plurality of reflection signals (150a, 150b, 150c) to a respective expected signal to monitor for degradation of the optical components (104, 106, 110, 112, 114, 122); detecting degradation of an optical component based on the comparison; receiving, at the receiver photodetector, a further reflection signal indicative of a portion of the beam reflected by the cloud; and detecting the presence of the cloud based on receiving the further reflection signal; wherein the comparing and detecting are performed by a processor operatively coupled to a memory. emitting a pulsed light beam from a laser through the external window towards a cloud; receiving a plurality of reflection signals, wherein the plurality of reflection signals includes a pair of reflection signals (150b,150c), received at a photodetector measuring reflection off of the external window and at a receiver photodetector, indicative of a portion of the beam reflected by the external window and a reflection signal, received at a trigger photodiode, indicative of portion of the beam reflected by transmitter optics; comparing the plurality of reflection signals (150a, 150b, 150c) to a respective expected signal to monitor for degradation of the optical components (104, 106, 110, 112, 114, 122); detecting degradation of an optical component based on the comparison; receiving, at the receiver photodetector, a further reflection signal indicative of a portion of the beam reflected by the cloud; and detecting the presence of the cloud based on receiving the further reflection signal; wherein the comparing and detecting are performed by a processor operatively coupled to a memory.
Method for heat treating a steel component in a targeted manner in individual component zones, it being possible for a predominantly austenitic structure to be produced in the steel component in one or more first regions, from which structure a predominantly martensitic structure can be produced by quenching, and a predominantly bainitic structure being used in one or more second regions, the steel component first being heated in a first furnace to a temperature above the AC3 temperature, the steel component then being transferred to a treatment station, where it can cool down during the transfer, and in the treatment station the one or more second regions of the steel component being cooled to a cooling stop temperature θ 2 during a treatment time t B, characterized in that the steel component is then transferred to a second furnace, in the second furnace a furnace temperature being set so that the different regions (210, 220) of the steel component approach the furnace temperature of the second furnace, in the second furnace the one or more first regions cooling to a temperature above the structural transformation start temperature θ 1 of the steel component, from which temperature structural transformations from the austenitic structure can start, and the temperature of the one or more second regions rising again to a temperature below the AC3 temperature.
A method of depositing a multilayer coating onto a substrate, said method comprising: configuring a device to comprise: a cluster section configured to deposit at least one inorganic layer onto said substrate; an in-line section configured to deposit at least one organic layer onto said substrate, said in-line section operatively coupled to said cluster section; and a reduced-pressure source placed in vacuum communication with at least said in-line section; loading said substrate into said device; depositing at least a portion of said inorganic material onto said substrate as a component of said multilayer coating; operating said reduced-pressure source to create an at least partially evacuated environment about said substrate during at least a portion of deposition of said organic layer onto said substrate; depositing at least a portion of said organic layer onto said substrate as a component of said multilayer coating; and curing said deposited organic layer. configuring a device to comprise: a cluster section configured to deposit at least one inorganic layer onto said substrate; an in-line section configured to deposit at least one organic layer onto said substrate, said in-line section operatively coupled to said cluster section; and a reduced-pressure source placed in vacuum communication with at least said in-line section; a cluster section configured to deposit at least one inorganic layer onto said substrate; an in-line section configured to deposit at least one organic layer onto said substrate, said in-line section operatively coupled to said cluster section; and a reduced-pressure source placed in vacuum communication with at least said in-line section; loading said substrate into said device; depositing at least a portion of said inorganic material onto said substrate as a component of said multilayer coating; operating said reduced-pressure source to create an at least partially evacuated environment about said substrate during at least a portion of deposition of said organic layer onto said substrate; depositing at least a portion of said organic layer onto said substrate as a component of said multilayer coating; and curing said deposited organic layer.
A compound for use in treating a disease selected from malaria, a mycobacterium avium complex, a mycobacterium tuberculosis, or a nocardia infection in a patient, where the compound is of the formula or a pharmaceutically acceptable salt thereof, wherein: R 10 is hydrogen; X is H; and Y is OR 7; where R 7 is a monosaccharide or disaccharide, alkyl, aryl, heteroaryl, acyl, or -C -NR 8 R 9, where R 8 and R 9 are each independently selected from the group consisting of hydrogen, hydroxy, alkyl, aralkyl, alkylaryl, heteroalkyl, aryl, heteroaryl, alkoxy, dimethylaminoalkyl, acyl, sulfonyl, ureido, and carbamoyl; or X and Y are taken together with the attached carbon to form carbonyl; V is -C -, -C(=NR 11)-, -CH(NR 12, R 13)-, or -N(R 14)CH 2 -, where N(R 14) is attached to the C-10 carbon; wherein R 11 is hydroxy or alkoxy, R 12 and R 13 are each independently selected from the group consisting of hydrogen, hydroxy, alkyl, aralkyl, alkylaryl, alkoxy, heteroalkyl, aryl, heteroaryl, dimethylaminoalkyl, acyl, sulfonyl, ureido, and carbamoyl; R 14 is hydrogen, hydroxy, alkyl, aralkyl, alkylaryl, alkoxy, heteroalkyl, aryl, heteroaryl, dimethylaminoalkyl, acyl, sulfonyl, ureido, or carbamoyl; W is H, F, Cl, Br, I, or OH; A is -CH 2 -, -C -, -C O-, -C NH-, -S 2 -, -S 2 NH-, -C NHS 2 -; B is -(CH 2) n - where n is an integer ranging from 0-10, or B is an unsaturated carbon chain of 2-10 carbons; and C is hydrogen, hydroxy, acyl, acyloxy, sulfonyl, ureido, or carbamoyl, or optionally substituted C 1 -C 12 alkyl, optionally substituted ar(C 1 -C 12 alkyl), optionally substituted C 1 -C 12 alkoxy, heteroalkyl, optionally substituted aryl, or optionally substituted heteroaryl. R 10 is hydrogen; X is H; and Y is OR 7; where R 7 is a monosaccharide or disaccharide, alkyl, aryl, heteroaryl, acyl, or -C -NR 8 R 9, where R 8 and R 9 are each independently selected from the group consisting of hydrogen, hydroxy, alkyl, aralkyl, alkylaryl, heteroalkyl, aryl, heteroaryl, alkoxy, dimethylaminoalkyl, acyl, sulfonyl, ureido, and carbamoyl; or X and Y are taken together with the attached carbon to form carbonyl; V is -C -, -C(=NR 11)-, -CH(NR 12, R 13)-, or -N(R 14)CH 2 -, where N(R 14) is attached to the C-10 carbon; wherein R 11 is hydroxy or alkoxy, R 12 and R 13 are each independently selected from the group consisting of hydrogen, hydroxy, alkyl, aralkyl, alkylaryl, alkoxy, heteroalkyl, aryl, heteroaryl, dimethylaminoalkyl, acyl, sulfonyl, ureido, and carbamoyl; R 14 is hydrogen, hydroxy, alkyl, aralkyl, alkylaryl, alkoxy, heteroalkyl, aryl, heteroaryl, dimethylaminoalkyl, acyl, sulfonyl, ureido, or carbamoyl; W is H, F, Cl, Br, I, or OH; A is -CH 2 -, -C -, -C O-, -C NH-, -S 2 -, -S 2 NH-, -C NHS 2 -; B is -(CH 2) n - where n is an integer ranging from 0-10, or B is an unsaturated carbon chain of 2-10 carbons; and C is hydrogen, hydroxy, acyl, acyloxy, sulfonyl, ureido, or carbamoyl, or optionally substituted C 1 -C 12 alkyl, optionally substituted ar(C 1 -C 12 alkyl), optionally substituted C 1 -C 12 alkoxy, heteroalkyl, optionally substituted aryl, or optionally substituted heteroaryl.
A composition comprising a food product and supernatant fluid collected from a mycelial liquid tissue culture, wherein the amount of supernatant fluid is sufficient to enhance the food product's taste, wherein the improved taste comprises reduced bitter tastes, reduced undesirable aftertastes, and/or reduced astringency.
A method for manufacturing a fluid-impermeable container containing a receptacle for transporting a biological sample, comprising the steps of: a. folding a blank to form the container, the container comprising folded sheet material, the folded sheet material being fluid impermeable and defining a base, enclosing side walls (18a, 18b), an upper wall, and a container closing member, the upper wall being configured to define an opening to a recess for receiving a receptacle containing a biological sample to be transported, wherein the recess is sealingly enclosed by the container closing member when the container is in a closed configuration; b. inserting a receptacle into the container; characterised int that the method comprises further the steps of: c. applying a transparent plastic film around the container and receptacle; and d. applying a unique identifier to the receptacle and/or container through the film by contactless printing, wherein the unique identifier is one or more item of information which is specific to the source of the sample. a. folding a blank to form the container, the container comprising folded sheet material, the folded sheet material being fluid impermeable and defining a base, enclosing side walls (18a, 18b), an upper wall, and a container closing member, the upper wall being configured to define an opening to a recess for receiving a receptacle containing a biological sample to be transported, wherein the recess is sealingly enclosed by the container closing member when the container is in a closed configuration; b. inserting a receptacle into the container; characterised int that the method comprises further the steps of: c. applying a transparent plastic film around the container and receptacle; and d. applying a unique identifier to the receptacle and/or container through the film by contactless printing, wherein the unique identifier is one or more item of information which is specific to the source of the sample.
Tyre comprising a tread, a crown with a crown reinforcement, two sidewalls, two beads and a carcass reinforcement anchored to the two beads and extending from one sidewall to the other, characterized in that the tread comprises at least one thermoplastic elastomer, the said thermoplastic elastomer being a block copolymer comprising at least one elastomer block and at least one thermoplastic block, and the total content of thermoplastic elastomer being within a range varying from 65 to 100 phr (parts by weight per hundred parts of elastomer).
A method for assessing the field of vision, wherein FDF stimuli are displayed and perceived by a person having the at least one eye to be examined; the display of the FDF stimuli is carried out using a computer-controlled system to determine visual function efficiently; each FDF stimulus is generated using an image generation unit; the functional changes in the eye are assessed and/or sensed; a combination with a method for sensing structures and/or structural changes in the eye is carried out; a structural-functional analysis is carried out, wherein firstly the structure or a part of the structure of the eye is assessed and secondly specified sections of the structure are assigned to defined and/or specified regions of the field of vision, characterised in that - each section of the optic nerve papilla or of another structure and each region of the field of vision are allocated to one of two or more categories, - wherein an image of the optic nerve papilla or of the other structure is displayed and divided into two or more sections, - wherein two rings (21, 22) are displayed and divided into the same sections, - wherein an inner ring indicates the result of the structural classification for each section of the optic nerve papilla or of the other structure by means of a colour code, graphical patterns or brightness gradations, and - wherein an outer ring in the same colour code, corresponding graphical patterns or brightness gradations indicates the classification result for the region of the field of vision corresponding to a section of the optic nerve papilla or of the other structure. - each section of the optic nerve papilla or of another structure and each region of the field of vision are allocated to one of two or more categories, - wherein an image of the optic nerve papilla or of the other structure is displayed and divided into two or more sections, - wherein two rings (21, 22) are displayed and divided into the same sections, - wherein an inner ring indicates the result of the structural classification for each section of the optic nerve papilla or of the other structure by means of a colour code, graphical patterns or brightness gradations, and - wherein an outer ring in the same colour code, corresponding graphical patterns or brightness gradations indicates the classification result for the region of the field of vision corresponding to a section of the optic nerve papilla or of the other structure.
A method of slickwater fracturing comprising introducing into a wellbore penetrating a subterranean formation an aqueous fracturing fluid at a pressure sufficient to create or enlarge a fracture in the subterranean formation, the fluid comprising: a) a nonionic polymer that is not polyethylene oxide; and b) polyethylene oxide; the amount of nonionic polymer employed is between from 0.1 to 5 pounds per 1,000 gallons of water (from 12 to 600 g per 1,000 litres of water) in the fluid; wherein the weight ratio of the polyethylene oxide and nonionic polymer in the fracturing fluid is between 20: 1 to 1: 20; wherein the weight average molecular weight of the polyethylene oxide is from 1 M to 20 M; and wherein the amount of polyethylene oxide is from 20 ppm to 400 ppm in the fracturing fluid. a) a nonionic polymer that is not polyethylene oxide; and b) polyethylene oxide;
A workstation comprising: a receiver configured to receive identification information of an X-ray detector from the X-ray detector; a controller configured to set information that indicates a color as assign indicator information of the X-ray detector, based on the received identification information of the X-ray detector; an output unit configured to display an X-ray detector icon including a sub-icon representing position information about the current position of the X-ray detector and the assign indicator of said color; and a transmitter configured to transmit the set information that indicates the color to the X-ray detector. a receiver configured to receive identification information of an X-ray detector from the X-ray detector; a controller configured to set information that indicates a color as assign indicator information of the X-ray detector, based on the received identification information of the X-ray detector; an output unit configured to display an X-ray detector icon including a sub-icon representing position information about the current position of the X-ray detector and the assign indicator of said color; and a transmitter configured to transmit the set information that indicates the color to the X-ray detector.
Biopsy forceps, in particular puncture biopsy forceps, the biopsy forceps comprising a forceps head, the biopsy forceps comprising a first pull/push part, on the distal longitudinal end of which the forceps head is attached, the biopsy forceps comprising flexible sheathing which has a hollow conduit through which the first pull/push part is longitudinally displaceably guided relative to the flexible sheathing, the biopsy forceps comprising a handling device which has a holding device and a first actuation device, the holding device and the first actuation device together forming a first longitudinal guide, by means of which the first actuation device is displaceably guided on the holding device, relative thereto, in an actuation direction, the flexible sheathing being connected, in particular at its proximal longitudinal end, to the holding device, the first pull/push part being connected, in particular at its proximal longitudinal end, to the first actuation device, the biopsy forceps comprising a path-limiting device, which can be detachably fastened to the first longitudinal guide at positions that can be selected on the basis of the stated actuation direction, and which, in the fastened state, forms a stop which limits a displacement path of the first actuation device in the distal direction relative to the holding device, the holding device comprising a guide core, the first actuation device comprising a guide sleeve, the guide core and the guide sleeve together forming the first longitudinal guide, the path-limiting device comprising a sleeve which is pushed onto the guide core, the sleeve comprising in its wall a threaded hole into which a clamping screw is screwed, the sleeve being displaceable on the guide core when the clamping screw is loosened and the sleeve being fixed on the guide core when the clamping screw is tightened, characterised in that a plurality of markings, in particular numbers, which are spaced apart from one another in the actuation direction, are applied to the guide core, the sleeve comprising a cut out through which the markings can be read.
An adjustment mechanism assembly for adjusting a work surface position vertically, comprising - a non-telescopic vertical guiding element (6, 6a, 6b) consisting of one vertical guiding member, - a work surface support element (8, 8a, 8b) engaged with the vertical guiding element and configured to be movable vertically with electric actuation, which work surface support element is arranged to protrude horizontally from within the vertical guiding element between the ends of the vertical guiding element, - means for said electric actuation comprising a cable, and - a non-telescopic vertical support member (3, 3a, 3b, 3c, 3d) which resides at least partially within the vertical guiding element, - which cable comprises a spiraled portion between its termini, which spiraled portion is supported with respect to its central axis by the vertical support member. - a non-telescopic vertical guiding element (6, 6a, 6b) consisting of one vertical guiding member, - a work surface support element (8, 8a, 8b) engaged with the vertical guiding element and configured to be movable vertically with electric actuation, which work surface support element is arranged to protrude horizontally from within the vertical guiding element between the ends of the vertical guiding element, - means for said electric actuation comprising a cable, and - a non-telescopic vertical support member (3, 3a, 3b, 3c, 3d) which resides at least partially within the vertical guiding element, - which cable comprises a spiraled portion between its termini, which spiraled portion is supported with respect to its central axis by the vertical support member.
A recombinant microorganism of the genus Escherichia producing quinolinic acid, wherein the activity of the protein having a sequence of SEQ ID NO: 1 is attenuated or eliminated, wherein an activity of quinolinate phosphoribosyltransferase is attenuated or eliminated and an activity of at least one enzyme selected from the group consisting of L-aspartate oxidase and quinolinate synthase is enhanced.
A pharmaceutical composition for use in treating graft-vs-host disease (GVHD) in a human patient, wherein the pharmaceutical composition comprises a therapeutically effective amount of a population of modified human regulatory T cells (Treg cells), wherein the human Treg cells are modified to express a nucleic acid sequence that encodes a chimeric antigen receptor construct, wherein the CAR construct comprises an antigen binding domain, wherein the antigen binding domain is specific for CD 19.
A method of constructing a modular building, the method including the following sequential steps: constructing a multi-floor building frame by connecting a plurality of like open topped-trays and column assemblies, with the trays forming floors and the column assemblies separating the floors; assembling walls or walls formwork to the frame; and thenpouring wet concrete into the trays to form the building, characterized in that the wet concrete is poured into all of the trays and then allowed to cure. constructing a multi-floor building frame by connecting a plurality of like open topped-trays and column assemblies, with the trays forming floors and the column assemblies separating the floors; assembling walls or walls formwork to the frame; and thenpouring wet concrete into the trays to form the building, characterized in that the wet concrete is poured into all of the trays and then allowed to cure.
Solar installation, in particular for water heating and/or heating assistance, having a plurality of solar collectors in at least one collector array, optionally direct transfer of solar energy via a plate heat exchanger or via a buffer store, at least two heat consumers with in each case one heat accumulator (5, 5'), in each case with a local regulating device (6, 6') for detecting energy data of the heat consumers, with a superordinate regulating device for the at least one collector array and a heat distribution network, which superordinate regulating device is linked to the local regulating devices (6, 6') of the heat consumers, the heat distribution network having connecting lines with at least one pump for a heat exchange medium for distributing the available energy quantity to the heat consumers, the local regulating devices (6, 6') being linked to the superordinate regulating device via a communications device, in each case having a local identifier, and it being possible for the volume of the respectively associated heat accumulator (5, 5') to be input at the local regulating devices (6, 6') of the heat consumers, characterized in that the solar installation is configured to transfer the locally input value for the volume of the respectively associated heat accumulator (5, 5') to the superordinate regulating device, the superordinate regulating device being configured to evaluate and to process both individual volume (that is to say, the individual values for the consumer-side heat accumulator volumes) and overall volume (that is to say, the total sum of the consumer-side heat accumulator volumes).