A catheter configured to extend through a transseptal puncture site, a left atrium, a mitral valve, and into a left ventricle, said catheter comprising: a shaft defining at least one lumen configured to receive at least one of an implant and/or a dilator, said shaft comprising a proximal end and a distal end; a first steerable device coupled to said shaft at a position that is about 3.8 to about 10.2 centimeters from a distal end of said shaft; a second steerable device coupled to said shaft at a position distal to said first steerable device and proximate to said distal end of said shaft; a handle assembly coupled to the proximal end of said shaft, said handle assembly comprising a first actuator coupled to said first steerable device and a second actuator coupled to said second steerable device; wherein: said first actuator is configured to apply a force to said first steerable device to deflect said shaft in a first region of said shaft proximate to said first steerable device; said second actuator is configured to apply a force to said second steerable device to deflect said shaft in a second region of said shaft proximate to said second steerable device; a section of said shaft is defined between said first steerable device and said proximal end, said section comprising a spiral reinforced section that extends from said first steerable device towards said handle assembly and a braided reinforced section extending from a proximal end of the spiral reinforced section to the handle assembly; said spiral reinforced section is configured to provide kink resistance when deflecting the shaft; and said braided reinforced section is configured to increase the pushability and torsional strength of the shaft while reducing kinking. a shaft defining at least one lumen configured to receive at least one of an implant and/or a dilator, said shaft comprising a proximal end and a distal end; a first steerable device coupled to said shaft at a position that is about 3.8 to about 10.2 centimeters from a distal end of said shaft; a second steerable device coupled to said shaft at a position distal to said first steerable device and proximate to said distal end of said shaft; a handle assembly coupled to the proximal end of said shaft, said handle assembly comprising a first actuator coupled to said first steerable device and a second actuator coupled to said second steerable device; wherein: said first actuator is configured to apply a force to said first steerable device to deflect said shaft in a first region of said shaft proximate to said first steerable device; said second actuator is configured to apply a force to said second steerable device to deflect said shaft in a second region of said shaft proximate to said second steerable device; a section of said shaft is defined between said first steerable device and said proximal end, said section comprising a spiral reinforced section that extends from said first steerable device towards said handle assembly and a braided reinforced section extending from a proximal end of the spiral reinforced section to the handle assembly; said first actuator is configured to apply a force to said first steerable device to deflect said shaft in a first region of said shaft proximate to said first steerable device; said second actuator is configured to apply a force to said second steerable device to deflect said shaft in a second region of said shaft proximate to said second steerable device; a section of said shaft is defined between said first steerable device and said proximal end, said section comprising a spiral reinforced section that extends from said first steerable device towards said handle assembly and a braided reinforced section extending from a proximal end of the spiral reinforced section to the handle assembly; said spiral reinforced section is configured to provide kink resistance when deflecting the shaft; and said braided reinforced section is configured to increase the pushability and torsional strength of the shaft while reducing kinking.