A device for packaging of products designed to keep said products in a determined temperature range, comprising - a plurality of thermal insulation panels arranged to form a box of parallelepipedic form, said box having a front face, a rear face opposite the front face, and four peripheral faces (30, 40, 50, 60) perpendicular in pairs and facing each-other in pairs and each extending between the front face and the rear face; - said front face being mobile relative to the peripheral faces (30, 40, 50, 60) so as to form a main opening allowing access to an internal space of the box for the packaging of the products, - at least one of the peripheral faces (30, 40, 50, 60) comprising at least one peripheral housing designed to receive at least one thermal stabilisation element, said at least one of the peripheral faces comprising at least one sheathed thermal insulation panel oriented such that the peripheral housing formed by the sheath is accessible from the main opening of the box, - the rear face also comprising at least one rear housing designed to receive at least one thermal stabilisation element, - the device comprising at least one rear opening formed along an edge between the rear face and one of the peripheral faces, said rear opening being provided to allow access to the rear housing of the rear face from the exterior of the box, and the device further comprising a removable closing element designed to close said rear opening, characterized in that the thermal insulation panels are arranged so as to allow access to the housings designed to receive the thermal stabilisation elements without opening the internal space for packaging the products, the front face comprising an intermediate plate designed to be positioned between the four peripheral faces to close access inside the box while leaving free access to the peripheral housing of the peripheral face, the intermediate plate comprising at least one front housing designed to receive at least one thermal stabilisation element, with access to said front housing being provided at the surface of the intermediate plate designed to be oriented towards the exterior of the box. - a plurality of thermal insulation panels arranged to form a box of parallelepipedic form, said box having a front face, a rear face opposite the front face, and four peripheral faces (30, 40, 50, 60) perpendicular in pairs and facing each-other in pairs and each extending between the front face and the rear face; - said front face being mobile relative to the peripheral faces (30, 40, 50, 60) so as to form a main opening allowing access to an internal space of the box for the packaging of the products, - at least one of the peripheral faces (30, 40, 50, 60) comprising at least one peripheral housing designed to receive at least one thermal stabilisation element, said at least one of the peripheral faces comprising at least one sheathed thermal insulation panel oriented such that the peripheral housing formed by the sheath is accessible from the main opening of the box, - the rear face also comprising at least one rear housing designed to receive at least one thermal stabilisation element, - the device comprising at least one rear opening formed along an edge between the rear face and one of the peripheral faces, said rear opening being provided to allow access to the rear housing of the rear face from the exterior of the box, and the device further comprising a removable closing element designed to close said rear opening,