mhurhangee/ep-ind-claims huggingface dataset:
An oral dosage form, other than a 50g or 75g dose of glucose, allowing large dose combinations of two or more health ingredients selected from water soluble, water insoluble and/ or lipid-based ingredients to be formulated together in a single dosage form, which is a drinkable gel with a volume of between 25ml and 250ml, wherein the health ingredients are retained in a delivery system comprising: • water, • a gelling agent, which is a carbohydrate non-ionic gelled polymer gelling agent and a polyvalent ion gelled polymer gelling agent, and • a pH adjuster wherein the carbohydrate non-ionic gelled polymer gelling agent is an agarose-based polymer gelling agent, the polyvalent ion gelled polymer gelling agent is an alginate-based polymer gelling agent and the agarose-based polymer gelling agent and alginate-based polymer gelling agent are present in a ratio of 5:1 to 1:1, and are present in amounts which ensure hydration of, and the formation of a firm gel with a bloom grade of between 100 and 250, and which does not exhibit plastic behaviour upon stress, but rather behaves elastically upon stress, to a failure point where the structure of the gel breaks or shears to irreversibly create new interfaces, making it more fluid when ingested, such that it is a drinkable gel. which is a drinkable gel with a volume of between 25ml and 250ml, wherein the health ingredients are retained in a delivery system comprising: • water, • a gelling agent, which is a carbohydrate non-ionic gelled polymer gelling agent and a polyvalent ion gelled polymer gelling agent, and • a pH adjuster • water, • a gelling agent, which is a carbohydrate non-ionic gelled polymer gelling agent and a polyvalent ion gelled polymer gelling agent, and • a pH adjuster wherein the carbohydrate non-ionic gelled polymer gelling agent is an agarose-based polymer gelling agent, the polyvalent ion gelled polymer gelling agent is an alginate-based polymer gelling agent and the agarose-based polymer gelling agent and alginate-based polymer gelling agent are present in a ratio of 5:1 to 1:1, and are present in amounts which ensure hydration of, and the formation of a firm gel with a bloom grade of between 100 and 250, and which does not exhibit plastic behaviour upon stress, but rather behaves elastically upon stress, to a failure point where the structure of the gel breaks or shears to irreversibly create new interfaces, making it more fluid when ingested, such that it is a drinkable gel.
A device for measuring a parameter of living tissue, in particular a glucose level, which parameter affects a response of said tissue to an electric field, said device comprising a substrate, an electrode arrangement (10, 12a, 12b, 13a - 13c, 14) comprising at least a first and a second electrode and being mounted on a first side of said substrate, wherein said first and second electrodes are separated by a gap, a control unit adapted to determine the response of said tissue to the electric field generated by said electrodes, wherein said gap is filled at least partially with a solid, wherein said device further comprises at least one optical reflection sensor (23a - c), wherein said at least one optical reflection sensor (23a - c) extends into said gap, characterized in that said optical reflection sensor (23a - c) extends through an opening in said substrate, wherein said opening ends in said gap.
A medical implement for forming a bore in a bone, the implement comprising: a handle having a proximal end for manual grasping and a distal end for engagement with a bone; a core slidably received in said handle, the core defining a passageway for receiving a drill for making a second bore in the bone; and a locking mechanism for clamping the passageway against the bone, characterized in that the implement further comprises a hook for inserting in a first bore in the bone, wherein said locking mechanism consists of a first and a second element which clamp the bone between them and wherein said first element is the hook inserted into the first bore and the second element is the core, wherein said locking mechanism further includes a resilient member coupled to said second element. a handle having a proximal end for manual grasping and a distal end for engagement with a bone; a core slidably received in said handle, the core defining a passageway for receiving a drill for making a second bore in the bone; and a locking mechanism for clamping the passageway against the bone, characterized in that the implement further comprises a hook for inserting in a first bore in the bone, wherein said locking mechanism consists of a first and a second element which clamp the bone between them and wherein said first element is the hook inserted into the first bore and the second element is the core, wherein said locking mechanism further includes a resilient member coupled to said second element.
A composition comprising: 5-(1-methylpyrazol-4-yl)2-naphthoylguanidine or (6-(1-methylpyrazol-4-yl)-2-nahpthoyl)guanidine, or a pharmaceutically acceptable salt thereof, and IFN α-2b, wherein: 5-(1-methylpyrazol-4-yl)2-naphthoylguanidine has the structure and (6-(1-methylpyrazol-4-yl)-2-naphthoyl)guanidine has the structure 5-(1-methylpyrazol-4-yl)2-naphthoylguanidine or (6-(1-methylpyrazol-4-yl)-2-nahpthoyl)guanidine, or a pharmaceutically acceptable salt thereof, and IFN α-2b, wherein: 5-(1-methylpyrazol-4-yl)2-naphthoylguanidine has the structure and (6-(1-methylpyrazol-4-yl)-2-naphthoyl)guanidine has the structure 5-(1-methylpyrazol-4-yl)2-naphthoylguanidine has the structure and (6-(1-methylpyrazol-4-yl)-2-naphthoyl)guanidine has the structure
Rotor control system for actuating pitch of pitch adjustable rotor blades of a wind turbine, the rotor control system comprises a pitch actuating unit for determining a pitch modification signal to be applied to a pitch actuator for actuating the pitch of the pitch adjustable rotor blades; the pitch actuation unit being arranged to: receive an edgewise load signal for each of the adjustable rotor blades, the edgewise load signal being measured in a rotating reference frame; apply an m-blade coordinate transformation to the edgewise load signal to transform the signal to a whirling reference frame along a first and a second reference direction; select the signal component of either the first or the second reference direction to obtain a selected signal component; filter the selected signal component at either a backward whirling frequency or a forward whirling frequency to obtain a filtered signal component; apply an inverse m-blade coordinate transformation to the filtered signal component to obtain the pitch modification signal; apply the pitch modification signal to the pitch actuator. receive an edgewise load signal for each of the adjustable rotor blades, the edgewise load signal being measured in a rotating reference frame; apply an m-blade coordinate transformation to the edgewise load signal to transform the signal to a whirling reference frame along a first and a second reference direction; select the signal component of either the first or the second reference direction to obtain a selected signal component; filter the selected signal component at either a backward whirling frequency or a forward whirling frequency to obtain a filtered signal component; apply an inverse m-blade coordinate transformation to the filtered signal component to obtain the pitch modification signal; apply the pitch modification signal to the pitch actuator.
A laser microdissection apparatus, comprising: a transfer film carrier having a substrate surface; and a laser microdissection transfer film coupled to the substrate surface of the transfer film carrier; characterised in that scattering media (930,940) is incorporated into said transfer film carrier and/or the LCM transfer film. a transfer film carrier having a substrate surface; and a laser microdissection transfer film coupled to the substrate surface of the transfer film carrier; characterised in that scattering media (930,940) is incorporated into said transfer film carrier and/or the LCM transfer film.
Sintered spherical BN particles comprising secondary particles formed of aggregated primary BN particles, wherein the number ratio of particles, each having a recess on its surface, is 50 % or more in the sintered spherical BN particles, wherein the recess has a size, which is defined by the recess ratio a/b, where a is the recess depth and b is the contour height of the BN particle having the recess, and wherein the recess ratio is in the range of 0.1 to 0.8. and each of the sintered spherical BN particles has a compressive strength of 2 MPa to 40 MPa.
An insertion system for inserting a self-expandable heart valve stent into the body of a patient, wherein the insertion system has the following: - a catheter system and a catheter tip provided at a proximal end portion of the catheter system; and - a handle (70-1, 70-2) provided at a distal end of the catheter system for manipulating the catheter tip, wherein the catheter tip comprises first and second housing portions (11, 21) for accomodating a self-expandable stent, and further comprises a stent holder for releasably fixing at least one region of a stent accomodated in the catheter tip; wherein the handle (70-1, 70-2) has at least a first and a second operating means (71, 81), with which the first and second housing portions (11, 21) of the catheter tip can be manipulated so that the first and second housing portions (11, 21) can be moved in opposite directions relative to the stent holder such that a self-expandable stent housed in the first and second housing portions (11, 21) can be released in steps in a previously defined or definable sequence of events from the catheter tip, wherein the at least one first operating means is designed to co-operate with the first housing portion of the catheter tip, and wherein the at least one second operating means is designed to co-operate with the second housing portion of the catheter tip; wherein the handle (70-1, 70-2) is provided with at least one injection adapter (99a, 99b); and wherein the stent holder is configured to form a releasable engagement with at least one retaining element of the self-expandable heart valve stent to be inserted into the body of the patient. - a catheter system and a catheter tip provided at a proximal end portion of the catheter system; and - a handle (70-1, 70-2) provided at a distal end of the catheter system for manipulating the catheter tip,
A method for forming a composite coating on a substrate comprising: applying a first coating composition to at least a portion of a surface of the substrate; and applying a second coating composition to at least a portion of the first coating formed in step prior to substantially heating or curing the first coating, to form a secondary coating thereon and yielding a composite coating; wherein the first and/or second coating composition is a waterborne curable film-forming composition comprising an aqueous dispersion of: (a) internally crosslinked polymeric microparticles having a core-shell morphology and having reactive functional groups; and (b) a crosslinking agent having functional groups reactive with functional groups on the polymeric microparticles; wherein the core of the polymeric microparticles is prepared from a monomer mixture comprising at least 20 percent by weight of a monomer having the structure: wherein X is N; R is a linear or branched alkyl group having 1 to 18 carbon atoms, or R is bonded to X to form a 5- to 7-member ring; based on the total weight of monomers in the monomer mixture. applying a first coating composition to at least a portion of a surface of the substrate; and applying a second coating composition to at least a portion of the first coating formed in step prior to substantially heating or curing the first coating, to form a secondary coating thereon and yielding a composite coating; wherein the first and/or second coating composition is a waterborne curable film-forming composition comprising an aqueous dispersion of: (a) internally crosslinked polymeric microparticles having a core-shell morphology and having reactive functional groups; and (b) a crosslinking agent having functional groups reactive with functional groups on the polymeric microparticles; wherein the core of the polymeric microparticles is prepared from a monomer mixture comprising at least 20 percent by weight of a monomer having the structure: wherein X is N; R is a linear or branched alkyl group having 1 to 18 carbon atoms, or R is bonded to X to form a 5- to 7-member ring; based on the total weight of monomers in the monomer mixture. (a) internally crosslinked polymeric microparticles having a core-shell morphology and having reactive functional groups; and (b) a crosslinking agent having functional groups reactive with functional groups on the polymeric microparticles;
Planar heating element with a PTC resistor structure, which is arranged in a defined surface area of a first surface of a carrier substrate, wherein electrical connection contacts are assigned to the PTC resistor structure for connection to an electrical voltage source, wherein the electrical connection contacts are connected to the PTC resistor structure via electrical connection lines, wherein the PTC resistor structure has a first end section, a middle section and a second end section, wherein, starting from a defined overlap, the PTC resistor structure is made from interlocking conductive tracks (8, 9) and has an interior conductive track and an exterior conductive track, wherein the interior conductive track and the exterior conductive track are essentially parallel in the middle section, wherein the interior conductive track and the exterior conductive track are switched in parallel, characterized in that the connection lines and the conductive tracks (8, 9) each have the defined overlap in the first end section of the PTC resistor structure, the interior conductive track has a bigger resistance than the exterior conductive track, the resistances of the interior conductive track and the exterior conductive track are sized in such a way that, when voltage is applied, there is an essentially even distribution of temperature within the defined surface area, and the first end section of the PTC resistor structure is designed in such a way, with regard to the filling thickness and/or the line width of the conductive tracks (8, 9) in the area of the specific overlap, that the physical heating properties of the PTC resistor structure are at least approximately unchanged in the first section. wherein, starting from a defined overlap, the PTC resistor structure is made from interlocking conductive tracks (8, 9) and has an interior conductive track and an exterior conductive track, wherein the interior conductive track and the exterior conductive track are essentially parallel in the middle section, wherein the interior conductive track and the exterior conductive track are switched in parallel, characterized in that the connection lines and the conductive tracks (8, 9) each have the defined overlap in the first end section of the PTC resistor structure, the interior conductive track has a bigger resistance than the exterior conductive track, the resistances of the interior conductive track and the exterior conductive track are sized in such a way that, when voltage is applied, there is an essentially even distribution of temperature within the defined surface area, and the first end section of the PTC resistor structure is designed in such a way, with regard to the filling thickness and/or the line width of the conductive tracks (8, 9) in the area of the specific overlap, that the physical heating properties of the PTC resistor structure are at least approximately unchanged in the first section.
Burner for a gas-heated cooking appliance, with a cover, a nozzle, a pipe for mixing burnable gas with primary air and a deflecting element which is arranged in the interior space bounded by the pipe, wherein one end of the pipe points towards the nozzle and its other end points towards the cover, characterised in that the deflecting element is arranged between and including a centre of the pipe in respect of a longitudinal direction thereof and the one end that points towards the nozzle, and wherein the deflecting element has at least one piece of wire (25, 26).
A method of displaying at least one operating menu of a cooking device on a touchscreen and of driving the cooking device, the operating menu having different menu levels, characterized in that in a first menu level, the following are displayed at the same time: a) a first overview field of at least one cooking chamber forming a flat heating surface and having directly selectable areas (42 - 52') in the first menu level for separate activation, and, additionally, at least one of the following overview fields, b) a second overview field having a plurality of different predefined cooking chamber subdivisions (56 - 66), which include different, separately activatable areas (42 - 52') of the cooking chamber, the predefined cooking chamber subdivisions (56 - 66) being directly selectable in the first menu level for activation; c) a third overview field having a plurality of different cooking applications (70 - 80), which are directly selectable in the first menu level for activation; and d) a fourth overview field having different, predefined cooking chamber subdivisions with already allocated cooking applications, which are directly selectable in the first menu level. a) a first overview field of at least one cooking chamber forming a flat heating surface and having directly selectable areas (42 - 52') in the first menu level for separate activation, and, additionally, at least one of the following overview fields, b) a second overview field having a plurality of different predefined cooking chamber subdivisions (56 - 66), which include different, separately activatable areas (42 - 52') of the cooking chamber, the predefined cooking chamber subdivisions (56 - 66) being directly selectable in the first menu level for activation; c) a third overview field having a plurality of different cooking applications (70 - 80), which are directly selectable in the first menu level for activation; and d) a fourth overview field having different, predefined cooking chamber subdivisions with already allocated cooking applications, which are directly selectable in the first menu level.
A method for analyzing spectral data produced by a detector that interrogates a substantially contained space for presence of one or more radioactive materials of interest, comprising: a. grouping materials expected to be in a detection path of the detector into one of a plurality of material groups based on similarities in cross sections of the materials; b. selecting data describing a representative energy versus cross section curve for each material group from cross sections of individual materials in the respective material group; c. computing interaction of each radioactive material of interest with one or more of the material groups using the representative energy versus cross section curve for the respective material groups to produce spectral data for the radioactive material of interest; d. generating a library of spectral data comprising the spectral data computed for each radioactive material of interest; and e. analyzing the spectral data produced by the detector against the library of spectral data to determine presence of a threat radioactive material in the space. a. grouping materials expected to be in a detection path of the detector into one of a plurality of material groups based on similarities in cross sections of the materials; b. selecting data describing a representative energy versus cross section curve for each material group from cross sections of individual materials in the respective material group; c. computing interaction of each radioactive material of interest with one or more of the material groups using the representative energy versus cross section curve for the respective material groups to produce spectral data for the radioactive material of interest; d. generating a library of spectral data comprising the spectral data computed for each radioactive material of interest; and e. analyzing the spectral data produced by the detector against the library of spectral data to determine presence of a threat radioactive material in the space.
An antiperspirant/deodorant composition comprising: a carrier comprising a polyhydric alcohol or a mixture of a polyhydric alcohol and water, wherein the polyhydric alcohol comprises an organic compound containing 2 to 6 carbon atoms and 2 to 6 hydroxy groups; a thickening agent comprising a C14-22 fatty acid salt, wherein the C14-22 fatty acid salt comprises at least one of an alkali metal, an alkaline earth metal, a transition metal, or an amine salt of C14-22 fatty acid; and an antiperspirant active consisting of one or more of a layered silicate clay and an acyl substituted polyvinylpyrrolidone having an acyl chain length ranging from 16 to 30 carbon atoms, wherein the antiperspirant/deodorant composition is essentially free of a C1-5 monohydric alcohol, wherein the composition does not contain any aluminum-based antiperspirant. a carrier comprising a polyhydric alcohol or a mixture of a polyhydric alcohol and water, wherein the polyhydric alcohol comprises an organic compound containing 2 to 6 carbon atoms and 2 to 6 hydroxy groups; a thickening agent comprising a C14-22 fatty acid salt, wherein the C14-22 fatty acid salt comprises at least one of an alkali metal, an alkaline earth metal, a transition metal, or an amine salt of C14-22 fatty acid; and an antiperspirant active consisting of one or more of a layered silicate clay and an acyl substituted polyvinylpyrrolidone having an acyl chain length ranging from 16 to 30 carbon atoms, wherein the antiperspirant/deodorant composition is essentially free of a C1-5 monohydric alcohol, wherein the composition does not contain any aluminum-based antiperspirant.
An isolated polypeptide consisting of a sequence of up to 20 amino acids, wherein said sequence comprising or consisting of a sequence selected from the group consisting of: - SEQ ID NO: 32; and - a sequence having at least 80% of identity with SEQ ID NO: 32 over the entire length of SEQ ID NO: 32; for use as a medicament in the treatment and/or prevention of a bone resorptive disease. - SEQ ID NO: 32; and - a sequence having at least 80% of identity with SEQ ID NO: 32 over the entire length of SEQ ID NO: 32;