A method for improved single molecule sequencing, the method comprising: preparing a set of unique molecular identifier -based molecules associated with a set of target nucleic acid sequences; facilitating generation a set of tagged nucleic acid molecules based on the set of UMI-based molecules and a set of nucleic acid molecules corresponding to the set of target nucleic acid sequences, wherein each tagged nucleic acid molecule of the set of tagged nucleic acid molecules comprises: a UMI region comprising a set of random "N" bases, wherein each random "N" base is selected from any one of an "A" base, a "G" base, a "T" base, and a "C" base; and a target region corresponding to a target nucleic acid sequence of the set of target nucleic acid sequences; and facilitating single molecule sequencing with the set of tagged nucleic acid molecules, wherein performing the single molecule sequencing comprises: determining a comparison between a first set of sequence regions and a second set of sequence regions, wherein the first set of sequence regions comprises a first UMI region and a first target region of a sequenced tagged nucleic acid molecule of the set of tagged nucleic acid molecules, and wherein the second set of sequence regions comprises a second UMI region and a second target region of a tagged nucleic acid molecule of the set of tagged nucleic acid molecules; and stopping sequencing of the tagged nucleic acid molecule based on the comparison between the first set of sequence regions and the second set of sequence regions. preparing a set of unique molecular identifier -based molecules associated with a set of target nucleic acid sequences; facilitating generation a set of tagged nucleic acid molecules based on the set of UMI-based molecules and a set of nucleic acid molecules corresponding to the set of target nucleic acid sequences, wherein each tagged nucleic acid molecule of the set of tagged nucleic acid molecules comprises: a UMI region comprising a set of random "N" bases, wherein each random "N" base is selected from any one of an "A" base, a "G" base, a "T" base, and a "C" base; and a target region corresponding to a target nucleic acid sequence of the set of target nucleic acid sequences; and a UMI region comprising a set of random "N" bases, wherein each random "N" base is selected from any one of an "A" base, a "G" base, a "T" base, and a "C" base; and a target region corresponding to a target nucleic acid sequence of the set of target nucleic acid sequences; and facilitating single molecule sequencing with the set of tagged nucleic acid molecules, wherein performing the single molecule sequencing comprises: determining a comparison between a first set of sequence regions and a second set of sequence regions, wherein the first set of sequence regions comprises a first UMI region and a first target region of a sequenced tagged nucleic acid molecule of the set of tagged nucleic acid molecules, and wherein the second set of sequence regions comprises a second UMI region and a second target region of a tagged nucleic acid molecule of the set of tagged nucleic acid molecules; and stopping sequencing of the tagged nucleic acid molecule based on the comparison between the first set of sequence regions and the second set of sequence regions. determining a comparison between a first set of sequence regions and a second set of sequence regions, wherein the first set of sequence regions comprises a first UMI region and a first target region of a sequenced tagged nucleic acid molecule of the set of tagged nucleic acid molecules, and wherein the second set of sequence regions comprises a second UMI region and a second target region of a tagged nucleic acid molecule of the set of tagged nucleic acid molecules; and stopping sequencing of the tagged nucleic acid molecule based on the comparison between the first set of sequence regions and the second set of sequence regions.