A compound of formula or formula: or a pharmaceutical salt thereof, wherein: HET is a saturated or unsaturated mono- or multi-ring carbocycle in which one or more of the ring carbon atoms is replaced by N, S, P or O; each R 1 is independently hydrogen; CF 3; phenyl optionally substituted with cyano, halo, nitro, hydroxyl, (C 1 -C 6)alkyl, (C 1 -C 6)alkyl-OH, (C1-C6)alkoxy, COR 3, NR 4 R 5 or NHCO(C1-C6) alkyl; cyano; halo; nitro; hydroxyl; (C1-C6)alkyl; (C1-C6)alkyl-OH; (C1-C6)alkoxy; (C1-C6)thioalkoxy; phenoxy; COR 3; NR 4 R 5; NHCO(C1-C6) alkyl; SO 2 (C1-C6) alkyl; or SO 2 NR 4 R 5; R 2 is H, R 6, COR 6, CONHR 6, COOR 6, CH 2 OCOR 6, P 2, P (O(C1-C6)alkyl) 2, P (OCH 2 OCO(C1-C6)alkyl) 2, P (OCH 2 OCO(C1-C6)alkyl), P (O(C1-C6)alkyl) P (C1-C6)alkyl, glycosyl or an inorganic salt of P 2, P (O(C1-C6)alkyl) 2, P (OCH 2 OCO(C1-C6)alkyl) 2, P (OCH 2 OCO(C1-C6)alkyl), P (OC1-C6)alkyl or P (C1-C6)alkyl; R 6 is C 1-C6 alkyl, trifluoromethyl, (C3-C6)cycloalkyl, cyclohexylmethyl or phenyl, wherein the phenyl is substituted with 0 to 4 groups selected from the group consisting of fluorine, chlorine, bromine, hydroxyl, trifluoromethyl, (C1-C4)alkyl, (C1-C4)alkoxy and phenylmethyl, wherein the phenylmethyl is substituted on the phenyl ring with 0-4 groups selected from the group consisting of fluorine, chlorine, bromine, hydroxyl, trifluoromethyl, (C1-C4)alkyl, (C1-C4)alkoxy, 2-pyridinyl, 3-pyridinyl, -4-pyridinyl, 2-pyrimidinyl, 4-pyrimidinyl, and 5-pyrimidinyl; R 3 is independently hydroxyl, (C1-C6)alkoxy, phenoxy or -NR 4 R 5; each R 4 and R 5 are independently hydrogen, (C1-C6)alkyl or (C3-C6)cycloalkyl; and n is 0-3, wherein on HET, there exists an ortho relationship between the OR 2 group and the amide moiety. HET is a saturated or unsaturated mono- or multi-ring carbocycle in which one or more of the ring carbon atoms is replaced by N, S, P or O; each R 1 is independently hydrogen; CF 3; phenyl optionally substituted with cyano, halo, nitro, hydroxyl, (C 1 -C 6)alkyl, (C 1 -C 6)alkyl-OH, (C1-C6)alkoxy, COR 3, NR 4 R 5 or NHCO(C1-C6) alkyl; cyano; halo; nitro; hydroxyl; (C1-C6)alkyl; (C1-C6)alkyl-OH; (C1-C6)alkoxy; (C1-C6)thioalkoxy; phenoxy; COR 3; NR 4 R 5; NHCO(C1-C6) alkyl; SO 2 (C1-C6) alkyl; or SO 2 NR 4 R 5; R 2 is H, R 6, COR 6, CONHR 6, COOR 6, CH 2 OCOR 6, P 2, P (O(C1-C6)alkyl) 2, P (OCH 2 OCO(C1-C6)alkyl) 2, P (OCH 2 OCO(C1-C6)alkyl), P (O(C1-C6)alkyl) P (C1-C6)alkyl, glycosyl or an inorganic salt of P 2, P (O(C1-C6)alkyl) 2, P (OCH 2 OCO(C1-C6)alkyl) 2, P (OCH 2 OCO(C1-C6)alkyl), P (OC1-C6)alkyl or P (C1-C6)alkyl; R 6 is C 1-C6 alkyl, trifluoromethyl, (C3-C6)cycloalkyl, cyclohexylmethyl or phenyl, wherein the phenyl is substituted with 0 to 4 groups selected from the group consisting of fluorine, chlorine, bromine, hydroxyl, trifluoromethyl, (C1-C4)alkyl, (C1-C4)alkoxy and phenylmethyl, wherein the phenylmethyl is substituted on the phenyl ring with 0-4 groups selected from the group consisting of fluorine, chlorine, bromine, hydroxyl, trifluoromethyl, (C1-C4)alkyl, (C1-C4)alkoxy, 2-pyridinyl, 3-pyridinyl, -4-pyridinyl, 2-pyrimidinyl, 4-pyrimidinyl, and 5-pyrimidinyl; R 3 is independently hydroxyl, (C1-C6)alkoxy, phenoxy or -NR 4 R 5; each R 4 and R 5 are independently hydrogen, (C1-C6)alkyl or (C3-C6)cycloalkyl; and n is 0-3, wherein on HET, there exists an ortho relationship between the OR 2 group and the amide moiety.