An infusion device (200,502) comprising a reservoir for fluid to be infused into a patient and a control system, the control system being configured to operate the infusion device to deliver the fluid in an automated manner in accordance with a first operating mode of a plurality of different operating modes, each operating mode of the plurality of different operating modes generating commands for delivering the fluid to the user in an automated manner in accordance with a different delivery control scheme associated therewith; to obtain operational information pertaining to the operating of the infusion device in accordance with the first operating mode; to obtain clinical information pertaining to the user; to determine a destination operating mode of the plurality of different operating modes based at least in part on the operational information and the clinical information; to transition operation of the infusion device from the first operating mode to the destination operating mode, wherein the destination operating mode is initialized using at least a portion of the operational information pertaining to the operating of the infusion device in accordance with the first operating mode; and to operate the infusion device to deliver the fluid in accordance with the destination operating mode in a manner that is influenced by the portion of the operational information pertaining to the first operating mode characterized in that the portion of the operational information includes sensor health information; and to determine the destination operating mode comprises: to identify a set of one or more possible operating modes of the plurality of different operating modes by excluding an operating mode of the plurality of different operating modes based on the sensor health information; and to select the destination operating mode from the set, wherein sensor health information is indicative that the sensing arrangement, which is communicatively coupled with the infusion device, is not viable for particular operating modes. to deliver the fluid in an automated manner in accordance with a first operating mode of a plurality of different operating modes, each operating mode of the plurality of different operating modes generating commands for delivering the fluid to the user in an automated manner in accordance with a different delivery control scheme associated therewith; to obtain operational information pertaining to the operating of the infusion device in accordance with the first operating mode; to obtain clinical information pertaining to the user; to determine a destination operating mode of the plurality of different operating modes based at least in part on the operational information and the clinical information; to transition operation of the infusion device from the first operating mode to the destination operating mode, wherein the destination operating mode is initialized using at least a portion of the operational information pertaining to the operating of the infusion device in accordance with the first operating mode; and to operate the infusion device to deliver the fluid in accordance with the destination operating mode in a manner that is influenced by the portion of the operational information pertaining to the first operating mode characterized in that the portion of the operational information includes sensor health information; and to determine the destination operating mode comprises: to identify a set of one or more possible operating modes of the plurality of different operating modes by excluding an operating mode of the plurality of different operating modes based on the sensor health information; and to select the destination operating mode from the set, wherein sensor health information is indicative that the sensing arrangement, which is communicatively coupled with the infusion device, is not viable for particular operating modes. to identify a set of one or more possible operating modes of the plurality of different operating modes by excluding an operating mode of the plurality of different operating modes based on the sensor health information; and to select the destination operating mode from the set, wherein sensor health information is indicative that the sensing arrangement, which is communicatively coupled with the infusion device, is not viable for particular operating modes.