A networked radio frequency identification system for localizing a radio frequency identification, RFID, tag at an endpoint, the system comprising: a network model having a plurality of endpoints and oriented links; a plurality of RFID tag readers (24a-c, 28, 32a-e, 34), one or more of the plurality of RFID tag readers being associated with a first endpoint of the plurality of endpoints, each RFID tag reader including at least one adjustable configuration setting selected from RF signal strength, antenna gain, antenna polarization, and antenna orientation, and each RFID tag reader including at least one radio frequency interrogator; a computer system communicatively coupled with the plurality of RFID tag readers over a network; and a software module operable by the computer that localizes RFID tags based on information received from the RFID tag readers characterized in that the computer system is configured to operate the software module to: assign weights to the adjustable configuration settings of each of the plurality of RFID tag readers; collect data for each of the plurality of RFID tag readers for each setting during an interval of time and apply the assigned setting weight to calculate an aggregation result for each RFID tag reader; aggregate the results calculated for each RFID tag reader to determine an aggregation result for the first endpoint; and compare the aggregation result for the first endpoint to at least one of a threshold value or a threshold interval to determine whether the RFID tag is localized at the first endpoint. a network model having a plurality of endpoints and oriented links; a plurality of RFID tag readers (24a-c, 28, 32a-e, 34), one or more of the plurality of RFID tag readers being associated with a first endpoint of the plurality of endpoints, each RFID tag reader including at least one adjustable configuration setting selected from RF signal strength, antenna gain, antenna polarization, and antenna orientation, and each RFID tag reader including at least one radio frequency interrogator; a computer system communicatively coupled with the plurality of RFID tag readers over a network; and a software module operable by the computer that localizes RFID tags based on information received from the RFID tag readers characterized in that the computer system is configured to operate the software module to: assign weights to the adjustable configuration settings of each of the plurality of RFID tag readers; collect data for each of the plurality of RFID tag readers for each setting during an interval of time and apply the assigned setting weight to calculate an aggregation result for each RFID tag reader; aggregate the results calculated for each RFID tag reader to determine an aggregation result for the first endpoint; and compare the aggregation result for the first endpoint to at least one of a threshold value or a threshold interval to determine whether the RFID tag is localized at the first endpoint. assign weights to the adjustable configuration settings of each of the plurality of RFID tag readers; collect data for each of the plurality of RFID tag readers for each setting during an interval of time and apply the assigned setting weight to calculate an aggregation result for each RFID tag reader; aggregate the results calculated for each RFID tag reader to determine an aggregation result for the first endpoint; and compare the aggregation result for the first endpoint to at least one of a threshold value or a threshold interval to determine whether the RFID tag is localized at the first endpoint.