mhurhangee/ep-ind-claims huggingface dataset:
A compound of Formula or pharmaceutically acceptable salts thereof wherein R and R 1 may be H, with the proviso that: when R= then R 1 = H and R 2 = CH 3 CO- or H; when R 1 = then R= H and R 2 = CH 3 CO- or H; when R = then R 1 = H and R 2 = CH 3 CO- or H; and when R 1 = then R = H and R 2 = CH 3 CO- or H; wherein R 3 and R 4 are the same or different and selected from the group comprising hydrogen, linear or branched C 1 -C 10 alkyl, optionally substituted with one or more substituents selected from aminoalkyl, alkoxy, phenoxy, or sulfo, and aryl, optionally mono- or disubstituted with C 1 -C 4 alkyl or alkoxy groups, halogen, amino, nitro; or R 3 and R 4 taken together with two consecutive carbon atoms of the pyridine core may form a phenyl ring, optionally substituted with C 1 -C 4 alkyl, or a 5- or 6-membered heterocyclic ring, optionally substituted with C 1 -C 4 alkyl, R 5 is selected from the group comprising hydrogen, hydroxy, linear or branched C 1 -C 10 alkyl, optionally substituted with one or more substituents selected from aminoalkyl, alkoxy, phenoxy, or sulfo, and aryl optionally mono- or disubstituted with C 1 -C 4 alkyl or alkoxy groups, halogen, amino, nitro. when R= then R 1 = H and R 2 = CH 3 CO- or H; when R 1 = then R= H and R 2 = CH 3 CO- or H; when R = then R 1 = H and R 2 = CH 3 CO- or H; and when R 1 = then R = H and R 2 = CH 3 CO- or H; wherein R 3 and R 4 are the same or different and selected from the group comprising hydrogen, linear or branched C 1 -C 10 alkyl, optionally substituted with one or more substituents selected from aminoalkyl, alkoxy, phenoxy, or sulfo, and aryl, optionally mono- or disubstituted with C 1 -C 4 alkyl or alkoxy groups, halogen, amino, nitro; or R 3 and R 4 taken together with two consecutive carbon atoms of the pyridine core may form a phenyl ring, optionally substituted with C 1 -C 4 alkyl, or a 5- or 6-membered heterocyclic ring, optionally substituted with C 1 -C 4 alkyl, R 5 is selected from the group comprising hydrogen, hydroxy, linear or branched C 1 -C 10 alkyl, optionally substituted with one or more substituents selected from aminoalkyl, alkoxy, phenoxy, or sulfo, and aryl optionally mono- or disubstituted with C 1 -C 4 alkyl or alkoxy groups, halogen, amino, nitro.
A method for making cases for firearms of the type comprising: - a substantially cylindrical pipe, made of a rigid material and delimited, at its first longitudinal end, by a substantially circular end edge; - a reinforcing element, made of plastically deformable material and inserted inside the first end of the pipe; and - a base, made of a rigid material, fitted on the first end of the pipe and having a substantially cylindrical shape, with a tubular side wall and with a bottom wall along whose perimeter edge the side wall of the base is flared outwards in such a way as to form a collar which has internally a seat undercut; wherein the reinforcing element is pre-shaped with a substantially cylindrical side wall and with a bottom wall along whose perimeter edge the side wall of the reinforcing element is flared outwards in such a way as to form a side anchoring tooth; the method comprises the steps of: - inserting the reinforcing element into the pipe until the anchoring tooth is brought substantially flush with the end edge of the first end of the pipe; - inserting the pipe and the reinforcing element into the base until the end edge of the first end of the pipe and the bottom wall of the reinforcing element are brought into contact with the bottom wall of the base; and - axially compressing the reinforcing element in such a way that by deforming plastically, it expands radially until securing the pipe against the inner side wall of the base, and until inserting the anchoring tooth inside the collar with the consequent radial deformation of the end edge of the first end of the pipe, which is thus secured, in flared configuration, between the anchoring tooth and the collar. - a substantially cylindrical pipe, made of a rigid material and delimited, at its first longitudinal end, by a substantially circular end edge; - a reinforcing element, made of plastically deformable material and inserted inside the first end of the pipe; and - a base, made of a rigid material, fitted on the first end of the pipe and having a substantially cylindrical shape, with a tubular side wall and with a bottom wall along whose perimeter edge the side wall of the base is flared outwards in such a way as to form a collar which has internally a seat undercut; - inserting the reinforcing element into the pipe until the anchoring tooth is brought substantially flush with the end edge of the first end of the pipe; - inserting the pipe and the reinforcing element into the base until the end edge of the first end of the pipe and the bottom wall of the reinforcing element are brought into contact with the bottom wall of the base; and - axially compressing the reinforcing element in such a way that by deforming plastically, it expands radially until securing the pipe against the inner side wall of the base, and until inserting the anchoring tooth inside the collar with the consequent radial deformation of the end edge of the first end of the pipe, which is thus secured, in flared configuration, between the anchoring tooth and the collar.
An entertainment system, comprising: a media source; a housing for supporting the media source, wherein the housing is coupled to an inner portion of a seat of a vehicle, and the media source is capable of being selectively connected to and disconnected from the housing; and a door pivotally attached to the housing with a first hinge, wherein when the door is open it reveals a display of the media source and when the door is closed it conceals the display of the media source, wherein the display is coupled to a base portion of the media source via an arm and the arm is coupled to the display via a second hinge and the arm is coupled to the base portion via a third hinge. a media source; a housing for supporting the media source, wherein the housing is coupled to an inner portion of a seat of a vehicle, and the media source is capable of being selectively connected to and disconnected from the housing; and a door pivotally attached to the housing with a first hinge, wherein when the door is open it reveals a display of the media source and when the door is closed it conceals the display of the media source, wherein the display is coupled to a base portion of the media source via an arm and the arm is coupled to the display via a second hinge and the arm is coupled to the base portion via a third hinge.
Method for producing an integrated microfluidic system, at least comprising a microfluidic substrate and an electronics substrate, in particular a semiconductor chip, the microfluidic substrate and the electronics substrate respectively having at least one fluidic connection element (2a, 3a) and at least one electrical connection element (2b, 3b) on a connecting surface, by means of a flip-chip connection, which comprises the following steps: A) applying a fluidically sealing adhesive for establishing fluidic contact to the connecting surface of the microfluidic substrate and/or of the electronics substrate; B) applying a second adhesive for electrical connection to the connecting surface of the microfluidic substrate and/or of the electronics substrate, the second adhesive being different from the first adhesive, C) placing the electronics substrate with its connecting surface onto the connecting surface of the microfluidic substrate and pressing it with a defined pressing pressure, the fluidic connection elements (2a, 3a) and electrical connection elements (2b, 3b) being arranged at least partially overlapping to create the fluidic and electrical contact, and D) curing the first and second adhesives (5, 6), characterized in that the second adhesive is cured first, in particular under the defined pressing pressure exerted in step C). A) applying a fluidically sealing adhesive for establishing fluidic contact to the connecting surface of the microfluidic substrate and/or of the electronics substrate; B) applying a second adhesive for electrical connection to the connecting surface of the microfluidic substrate and/or of the electronics substrate, the second adhesive being different from the first adhesive, C) placing the electronics substrate with its connecting surface onto the connecting surface of the microfluidic substrate and pressing it with a defined pressing pressure, the fluidic connection elements (2a, 3a) and electrical connection elements (2b, 3b) being arranged at least partially overlapping to create the fluidic and electrical contact, and D) curing the first and second adhesives (5, 6), characterized in that the second adhesive is cured first, in particular under the defined pressing pressure exerted in step C).
Valve device for transferring a transfer medium, with an inflow, an outflow and two valve discs (4, 4', 4", 5, 5', 5"), which are arranged one behind the other in flow direction and which are pivotable about a common axis of rotation for opening and closing the bore (22, 22', 22', 23, 23', 23") surrounding them, wherein the inflow and the outflow are formed by two housing members (6, 6", 7, 7"), which can be locked together and the mutually facing ends of which each receive a respective valve disc (4, 4', 4", 5, 5', 5") with a fixedly connected half shaft (11, 12), wherein in the locked state of the housing members (6, 6", 7, 7") the two half shafts (11, 12) form a common shaft pivotable about the axis of rotation and the valve discs (4, 4', 5, 5') bear tightly against one another, and wherein in the unlocked state of the housing members (6, 6", 7, 7") the valve discs (4, 4', 4", 5, 5', 5") each close the respective bore (22, 22', 22", 23, 23', 23") of the housing member (6, 6", 7, 7") receiving them, characterised in that two mutually opposite L-shaped cut-outs receiving the semicircular ends of the first half shaft are arranged in a wall of the lower end of the first housing member, wherein the first half shaft by pivotation about the longitudinal axis of the valve device is lockable by its ends in short limbs, which extend transversely to the longitudinal axis, of the L-shaped cut-outs, and ends of the second half shaft engage in long limbs, which extend parallel to the longitudinal axis, of the L-shaped cut-outs in a locked setting of the housing members (6, 7).
A starting system of an internal combustion engine, comprising (a) a combustion chamber, (b) an intake port and an exhaust port that communicate with the combustion chamber, (c) an intake valve and an exhaust valve that open and close the intake port and the exhaust port, respectively, (d) a throttle device provided in an intake passage that communicates with the intake port, the throttle device comprising a throttle valve, (e) fuel injecting means for injecting fuel into the combustion chamber, (f) igniting means for igniting an air/fuel mixture in the combustion chamber, and (g) crank angle sensing means for detecting a crank angle of the internal combustion engine, wherein: control means is provided for operating the throttle device to open the throttle valve to a predetermined throttle opening at a throttle opening speed that is set based on an intake pressure during stopping of the engine; the control means determines an expansion-stroke cylinder that is in an expansion stroke at the time of a start of the engine, based on the result of detection of the crank angle sensing means; and when the engine starts, the control means operates the fuel injecting means to inject the fuel into the expansion-stroke cylinder, and operates the igniting means to ignite the air/fuel mixture in the combustion chamber of the expansion-stroke cylinder. control means is provided for operating the throttle device to open the throttle valve to a predetermined throttle opening at a throttle opening speed that is set based on an intake pressure during stopping of the engine; the control means determines an expansion-stroke cylinder that is in an expansion stroke at the time of a start of the engine, based on the result of detection of the crank angle sensing means; and when the engine starts, the control means operates the fuel injecting means to inject the fuel into the expansion-stroke cylinder, and operates the igniting means to ignite the air/fuel mixture in the combustion chamber of the expansion-stroke cylinder.
A non-transitory computer readable medium comprising instructions which, when executed by one or more hardware processors, causes performance of operations comprising: dividing available storage in a filesystem into one or more contiguous allocation unit, AU, chunks, wherein each of the AU chunks comprises: a set of contiguous fixed-size AUs, wherein each AU in the set of contiguous fixed-size AUs comprises a series of contiguous fixed-size blocks; and a set of contiguous AU mappings that is adjacent to the set of contiguous fixed-size AUs, wherein each AU mapping in the set of contiguous AU mappings represents a different AU in the set of contiguous fixed-size AUs; storing, in a first AU mapping in the set of contiguous AU mappings, a first snapshot identifier for a snapshot of the filesystem to indicate allocation of a first AU represented by the first AU mapping to the snapshot; and allocating a first block in the first AU to the snapshot by incrementing, in the first AU mapping, a reference count that tracks a number of blocks in the first AU that are allocated to the snapshot. dividing available storage in a filesystem into one or more contiguous allocation unit, AU, chunks, wherein each of the AU chunks comprises: a set of contiguous fixed-size AUs, wherein each AU in the set of contiguous fixed-size AUs comprises a series of contiguous fixed-size blocks; and a set of contiguous AU mappings that is adjacent to the set of contiguous fixed-size AUs, wherein each AU mapping in the set of contiguous AU mappings represents a different AU in the set of contiguous fixed-size AUs; a set of contiguous fixed-size AUs, wherein each AU in the set of contiguous fixed-size AUs comprises a series of contiguous fixed-size blocks; and a set of contiguous AU mappings that is adjacent to the set of contiguous fixed-size AUs, wherein each AU mapping in the set of contiguous AU mappings represents a different AU in the set of contiguous fixed-size AUs; storing, in a first AU mapping in the set of contiguous AU mappings, a first snapshot identifier for a snapshot of the filesystem to indicate allocation of a first AU represented by the first AU mapping to the snapshot; and allocating a first block in the first AU to the snapshot by incrementing, in the first AU mapping, a reference count that tracks a number of blocks in the first AU that are allocated to the snapshot.
A spine alignment system (100, 200), comprising: a pedicle screw having a longitudinal axis, the pedicle screw having a screw head, wherein the screw head includes a threaded bore and a slot having a longitudinal axis that is substantially perpendicular to the longitudinal axis of the pedicle screw; an extension shaft secured to the pedicle screw, such that a longitudinal axis of the extension shaft is substantially coaxial with the longitudinal axis of the pedicle screw, said extension shaft including a longitudinal through-hole; an inner rod configured to be received within the longitudinal through-hole in the extension shaft, wherein the inner rod includes a threaded distal end configured to threadedly engage the threaded bore in the head of the pedicle screw; a cap having a through-hole configured to receive the extension shaft, the through-hole having a longitudinal axis, wherein the cap includes a slot having a longitudinal axis that is substantially perpendicular to the longitudinal axis of the through-hole, and wherein the slot of the screw head and the slot of the cap, together, form a substantially cylindrical passage configured to receive an alignment rod (140, 300); and, a nut configured to receive the extension shaft and facilitate movement of the cap along the extension shaft; and characterised in that the inner rod includes a stepped portion configured to abut the proximal end of the extension shaft thereby securing the extension shaft to the head of the pedicle screw. a pedicle screw having a longitudinal axis, the pedicle screw having a screw head, wherein the screw head includes a threaded bore and a slot having a longitudinal axis that is substantially perpendicular to the longitudinal axis of the pedicle screw; an extension shaft secured to the pedicle screw, such that a longitudinal axis of the extension shaft is substantially coaxial with the longitudinal axis of the pedicle screw, said extension shaft including a longitudinal through-hole; an inner rod configured to be received within the longitudinal through-hole in the extension shaft, wherein the inner rod includes a threaded distal end configured to threadedly engage the threaded bore in the head of the pedicle screw; a cap having a through-hole configured to receive the extension shaft, the through-hole having a longitudinal axis, wherein the cap includes a slot having a longitudinal axis that is substantially perpendicular to the longitudinal axis of the through-hole, and wherein the slot of the screw head and the slot of the cap, together, form a substantially cylindrical passage configured to receive an alignment rod (140, 300); and, a nut configured to receive the extension shaft and facilitate movement of the cap along the extension shaft; and characterised in that the inner rod includes a stepped portion configured to abut the proximal end of the extension shaft thereby securing the extension shaft to the head of the pedicle screw.
A device for removing material from inside a lumen of a tube, comprising: a catheter having a tubular body and defining an inner lumen and having a proximal end portion and a distal end portion, the distal end portion of the tubular body defining a distal opening, the proximal end portion of the catheter being configured to couple the inner lumen to a source of suction; the tubular body further defining one or more apertures on a sidewall of the tubular body, the apertures allowing fluid communication with the inner lumen of the catheter from outside the catheter; characterised by an expandable member attached to the distal end portion of the tubular body distal to the one or more apertures, the expandable member being capable of having a first unexpanded condition such that the distal opening is open to allow fluid communication with the inner lumen of the catheter through said distal opening, and a second expanded condition such that the distal opening is occluded to prevent fluid communication with the inner lumen of the catheter through said distal opening, the second expanded condition of the expandable member having a maximum transverse diameter larger than a diameter of the tubular body proximal to the expandable member. a catheter having a tubular body and defining an inner lumen and having a proximal end portion and a distal end portion, the distal end portion of the tubular body defining a distal opening, the proximal end portion of the catheter being configured to couple the inner lumen to a source of suction; the tubular body further defining one or more apertures on a sidewall of the tubular body, the apertures allowing fluid communication with the inner lumen of the catheter from outside the catheter; characterised by an expandable member attached to the distal end portion of the tubular body distal to the one or more apertures, the expandable member being capable of having a first unexpanded condition such that the distal opening is open to allow fluid communication with the inner lumen of the catheter through said distal opening, and a second expanded condition such that the distal opening is occluded to prevent fluid communication with the inner lumen of the catheter through said distal opening, the second expanded condition of the expandable member having a maximum transverse diameter larger than a diameter of the tubular body proximal to the expandable member. a first unexpanded condition such that the distal opening is open to allow fluid communication with the inner lumen of the catheter through said distal opening, and a second expanded condition such that the distal opening is occluded to prevent fluid communication with the inner lumen of the catheter through said distal opening, the second expanded condition of the expandable member having a maximum transverse diameter larger than a diameter of the tubular body proximal to the expandable member.
A modular skid assembly configured to transport at least one modular electrical component, the modular skid assembly comprising: a plate including an upper surface configured to support the at least one modular electrical component; a first side beam extending longitudinally along one side of the plate, the first side beam being secured to the plate; a second side beam extending longitudinally along an opposite side of the plate, the second side beam being secured to the plate; a plurality of joists extending laterally beneath the plate, the plurality of joists extending between the first side beam and the second side beam; characterised in that the modular skid assembly comprises: a first shipping beam configured to be releasably secured to the first side beam; and a second shipping beam configured to be releasably secured to the second side beam, wherein each of the first side beam and the second side beam includes a C-channel beam, and wherein each of the first shipping beam and the second shipping beam includes a C-channel beam, wherein, in use, the first shipping beam is positioned adjacent to the first side beam and the second shipping beam is positioned adjacent to the second side beam, wherein a lower flange of the first shipping beam extends laterally in an opposite direction to a lower flange of the first side beam, and a lower flange of the second shipping beam extends laterally in an opposite direction to a lower flange of the second side beam, and wherein a lower surface of the lower flange of the first shipping beam is flush with a lower surface of the lower flange of the first side beam, and a lower surface of the lower flange of the second shipping beam is flush with a lower surface of the lower flange of the second side beam. a plate including an upper surface configured to support the at least one modular electrical component; a first side beam extending longitudinally along one side of the plate, the first side beam being secured to the plate; a second side beam extending longitudinally along an opposite side of the plate, the second side beam being secured to the plate; a plurality of joists extending laterally beneath the plate, the plurality of joists extending between the first side beam and the second side beam;
A downhole cutting tool for enlarging the diameter of a hole, comprising a rotary tool body with at least one support member carrying cutters and projecting or extensible from the tool body, the support member comprising rotationally leading and trailing side faces and radially outward facing surfaces (211, 217) between the side faces, wherein a channel for fluid flow extends along the support member from one axial end of the support member to the other and crosses the outward facing surfaces (211, 217) with the channel intersecting the outward facing surfaces of the support member at rotationally leading and trailing edges of the channel, and characterised in that at least the rotationally trailing edge of the channel extends along the support member in a path which comprises a plurality of portions which are inclined at an angle of 10° to 45° relative to the tool axis and includes changes of inclination keeping the path within the width of the support member between its side faces.