A transpedicular anchoring screw, adapted for anchorage in a pedicle of a vertebra, including a screw body extending along a screw axis between a proximal end and a distal end, said screw body having a first thread and a second thread, each of said first thread and second thread being helical-shaped with a same screw pitch, extending between said proximal end and said distal end and having a convex-shaped outer edge, said transpedicular anchoring screw being characterized in that at least said first thread has, from the proximal end towards the distal end, at least: - a proximal portion, in which the outer edge of said first thread has a series of notched proximal portions, each defined by a proximal notch formed in said outer edge and inscribed within a notched proximal angular sector, wherein two successive notched proximal portions are separated from each other by a separation proximal portion, in which said outer edge is not notched and is inscribed within a separation proximal angular sector, and wherein, over a length of the first thread corresponding to one screw pitch, a ratio between the sum of the measurements of all of the separation proximal angular sectors and the sum of the measurements of all of the notched proximal angular sectors is comprised between 50% and 150%; and - a distal portion, in which the outer edge of said first thread has a series of notched distal portions, each defined by a distal notch formed in said outer edge and inscribed within a notched distal angular sector, wherein two successive notched distal portions are separated by a separation distal portion, in which said outer edge is not notched and is inscribed within a separation distal angular sector, and wherein, over a length of the first thread corresponding to one screw pitch, a ratio between the sum of the measurements of all of the separation distal angular sectors and the sum of the measurements of all of the notched distal angular sectors is comprised between 0% and 10%. said transpedicular anchoring screw being characterized in that at least said first thread has, from the proximal end towards the distal end, at least: - a proximal portion, in which the outer edge of said first thread has a series of notched proximal portions, each defined by a proximal notch formed in said outer edge and inscribed within a notched proximal angular sector, wherein two successive notched proximal portions are separated from each other by a separation proximal portion, in which said outer edge is not notched and is inscribed within a separation proximal angular sector, and wherein, over a length of the first thread corresponding to one screw pitch, a ratio between the sum of the measurements of all of the separation proximal angular sectors and the sum of the measurements of all of the notched proximal angular sectors is comprised between 50% and 150%; and - a distal portion, in which the outer edge of said first thread has a series of notched distal portions, each defined by a distal notch formed in said outer edge and inscribed within a notched distal angular sector, wherein two successive notched distal portions are separated by a separation distal portion, in which said outer edge is not notched and is inscribed within a separation distal angular sector, - a proximal portion, in which the outer edge of said first thread has a series of notched proximal portions, each defined by a proximal notch formed in said outer edge and inscribed within a notched proximal angular sector, wherein two successive notched proximal portions are separated from each other by a separation proximal portion, in which said outer edge is not notched and is inscribed within a separation proximal angular sector, and wherein, over a length of the first thread corresponding to one screw pitch, a ratio between the sum of the measurements of all of the separation proximal angular sectors and the sum of the measurements of all of the notched proximal angular sectors is comprised between 50% and 150%; and - a distal portion, in which the outer edge of said first thread has a series of notched distal portions, each defined by a distal notch formed in said outer edge and inscribed within a notched distal angular sector, wherein two successive notched distal portions are separated by a separation distal portion, in which said outer edge is not notched and is inscribed within a separation distal angular sector, and wherein, over a length of the first thread corresponding to one screw pitch, a ratio between the sum of the measurements of all of the separation distal angular sectors and the sum of the measurements of all of the notched distal angular sectors is comprised between 0% and 10%.