An automatic analysis device for measuring a specimen such as blood or urine, comprising: a B/F separation mechanism for performing a B/F separation process in which a bound component and a free component are separated using magnetic particles in a liquid which passes through a B/F separation passage and in which the specimen and the reagent have reacted with each other; a detection unit for detecting the reacted component in the liquid which has been subjected to the B/F separation process and passes through a detection passage; a control device including a determination unit for determining whether it is necessary to perform maintenance of at least one of the B/F separation passage, the detection passage and the detection unit, and a storage unit, and a display unit for displaying a message to prompt user to perform maintenance of the at least one of the B/F separation passage, the detection passage and the detection unit according to the determination of the determination unit, characterized in that the control device further includes an arithmetic unit adapted to calculate a passage load of the at least one of the B/F separation passage, the detection passage and the detection unit upon performing a present analysis protocol of the specimen, the passage load being based on main factors including at least one of the type of sample, the amount of a sample, components of a sample and the presence/absence of the B/F separation process before detection, and to calculate a total load of the at least one of the B/F separation passage, the detection passage and the detection unit as the sum of the passage loads in a number of previous analysis protocols and in the present analysis protocol, and the storage unit is adapted to store the total load calculated in the arithmetic unit, the determination unit is adapted to determine whether it is necessary to perform maintenance of the at least one of the B/F separation passage, the detection passage and the detection unit, by comparing the total load with a threshold value and by predicting a timing when the total load reaches the threshold value, on the basis of the progression of the total load stored in the storage unit, and the control device is adapted to output to the display unit display signals indicative of the comparison result and the timing obtained by the determination unit. a B/F separation mechanism for performing a B/F separation process in which a bound component and a free component are separated using magnetic particles in a liquid which passes through a B/F separation passage and in which the specimen and the reagent have reacted with each other; a detection unit for detecting the reacted component in the liquid which has been subjected to the B/F separation process and passes through a detection passage; a control device including a determination unit for determining whether it is necessary to perform maintenance of at least one of the B/F separation passage, the detection passage and the detection unit, and a storage unit, and a determination unit for determining whether it is necessary to perform maintenance of at least one of the B/F separation passage, the detection passage and the detection unit, and a storage unit, and a display unit for displaying a message to prompt user to perform maintenance of the at least one of the B/F separation passage, the detection passage and the detection unit according to the determination of the determination unit, characterized in that the control device further includes an arithmetic unit adapted to calculate a passage load of the at least one of the B/F separation passage, the detection passage and the detection unit upon performing a present analysis protocol of the specimen, the passage load being based on main factors including at least one of the type of sample, the amount of a sample, components of a sample and the presence/absence of the B/F separation process before detection, and to calculate a total load of the at least one of the B/F separation passage, the detection passage and the detection unit as the sum of the passage loads in a number of previous analysis protocols and in the present analysis protocol, and the storage unit is adapted to store the total load calculated in the arithmetic unit, the determination unit is adapted to determine whether it is necessary to perform maintenance of the at least one of the B/F separation passage, the detection passage and the detection unit, by comparing the total load with a threshold value and by predicting a timing when the total load reaches the threshold value, on the basis of the progression of the total load stored in the storage unit, and the control device is adapted to output to the display unit display signals indicative of the comparison result and the timing obtained by the determination unit.