A compound according to Formula, or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate thereof wherein: R 2 is independently selected from R 3a and R 3b are independently selected from H, CH 2 CH 3, CH 3, CH 2 OH, CH 2 CH 2 OH, CH 2 CH 2 OC 1-4 alkyl, CH 2 F, CHF 2, CH 2 CH 2 F, CF 3, CH 2 OCHF 2, CH 2 CN, CH 2 CH 2 CN, CH 2 OC 1-4 alkyl, C(CH 3) 3, CH(CH 3) 2, C(CH 3) 2 OH, C(CH 3) 2 F, C(=O)NH-C 3-6 cycloalkyl, C(=O)NH-heterocyclyl, and -CH 2 -heterocyclyl, wherein the heterocyclyl is independently selected from R 3c and R 3d are independently selected from H, CH 3, CH(CH 3) 2, CF 3, and C 3-6 cycloalkyl; R 5, at each occurrence, is independently selected from H, C 1-4 alkyl substituted with 0-3 R e, F, Cl, Br, -S p P c, -CN, -OR b, NR a R a, C 3-6 cycloalkyl, and aryl substituted with 0-3 R e; R 6 is independently selected from H and C 1-6 alkyl substituted with 0-5 R e; R 7, at each occurrence, is independently selected from H, F, Cl, Br, -(CH 2) r CN, NO 2, -(CH 2) r OR b, -S p R c, -C(=O)R b, -NR a R a, -C(=O)NR a R a, -NHC(=O)R b, -NHC(=O)OR b, -OC(=O)NR a R a, -NHC(=O)NR a R a, -C(=O)OR b, -S 2 NR A R A, -NHS 2 NR a R a, -NHS 2 R c, C 1-6 alkyl substituted with 0-5 R e, C 3-6 cycloalkyl substituted with 0-5 R e, aryl substituted with 0-5 R e, and heterocyclyl substituted with 0-5 R e; R 8, at each occurrence, is independently selected from H, F, Cl, Br, CN, C 1-6 alkyl substituted with 0-5 R e, -(CH 2) r -C 3-6 cycloalkyl substituted with 0-5 R e, -(CH 2) r -aryl substituted with 0-5 R e, -(CH 2) r -heterocyclyl substituted with 0-5 R e, CO 2 H, -(CH 2) r OR b, and -(CH 2) r NR a R a; R a, at each occurrence, is independently selected from H, CN, C 1-6 alkyl substituted with 0-5 R e, C 2-6 alkenyl substituted with 0-5 R e, C 2-6 alkynyl substituted with 0-5 R e, -(CH 2) r -C 310 carbocyclyl substituted with 0-5 R e, and -(CH 2) r -heterocyclyl substituted with 0-5 R e; or R a and R a together with the nitrogen atom to which they are both attached form a heterocyclic ring substituted with 0-5 R e; R b, at each occurrence, is independently selected from H, C 1-6 alkyl substituted with 0-5 R e, C 2-6 alkenyl substituted with 0-5 R e, C 2-6 alkynyl substituted with 0-5 R e, aryl substituted with 0-5 R e, and heterocyclyl substituted with 0-5 R e; R c, at each occurrence, is independently selected from C 1-6 alkyl substituted with 0-5 R e, C 3-6 carbocyclyl, and heterocyclyl; R e, at each occurrence, is independently selected from F, Cl, Br, CN, NO 2, =O, CO 2 H, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, and -(CH 2) r -C 3-6 cycloalkyl; p, at each occurrence, is independently selected from zero, 1, and 2; and r, at each occurrence, is independently selected from zero, 1, 2, 3, and 4. R 2 is independently selected from R 3a and R 3b are independently selected from H, CH 2 CH 3, CH 3, CH 2 OH, CH 2 CH 2 OH, CH 2 CH 2 OC 1-4 alkyl, CH 2 F, CHF 2, CH 2 CH 2 F, CF 3, CH 2 OCHF 2, CH 2 CN, CH 2 CH 2 CN, CH 2 OC 1-4 alkyl, C(CH 3) 3, CH(CH 3) 2, C(CH 3) 2 OH, C(CH 3) 2 F, C(=O)NH-C 3-6 cycloalkyl, C(=O)NH-heterocyclyl, and -CH 2 -heterocyclyl, wherein the heterocyclyl is independently selected from R 3c and R 3d are independently selected from H, CH 3, CH(CH 3) 2, CF 3, and C 3-6 cycloalkyl; R 5, at each occurrence, is independently selected from H, C 1-4 alkyl substituted with 0-3 R e, F, Cl, Br, -S p P c, -CN, -OR b, NR a R a, C 3-6 cycloalkyl, and aryl substituted with 0-3 R e; R 6 is independently selected from H and C 1-6 alkyl substituted with 0-5 R e; R 7, at each occurrence, is independently selected from H, F, Cl, Br, -(CH 2) r CN, NO 2, -(CH 2) r OR b, -S p R c, -C(=O)R b, -NR a R a, -C(=O)NR a R a, -NHC(=O)R b, -NHC(=O)OR b, -OC(=O)NR a R a, -NHC(=O)NR a R a, -C(=O)OR b, -S 2 NR A R A, -NHS 2 NR a R a, -NHS 2 R c, C 1-6 alkyl substituted with 0-5 R e, C 3-6 cycloalkyl substituted with 0-5 R e, aryl substituted with 0-5 R e, and heterocyclyl substituted with 0-5 R e; R 8, at each occurrence, is independently selected from H, F, Cl, Br, CN, C 1-6 alkyl substituted with 0-5 R e, -(CH 2) r -C 3-6 cycloalkyl substituted with 0-5 R e, -(CH 2) r -aryl substituted with 0-5 R e, -(CH 2) r -heterocyclyl substituted with 0-5 R e, CO 2 H, -(CH 2) r OR b, and -(CH 2) r NR a R a; R a, at each occurrence, is independently selected from H, CN, C 1-6 alkyl substituted with 0-5 R e, C 2-6 alkenyl substituted with 0-5 R e, C 2-6 alkynyl substituted with 0-5 R e, -(CH 2) r -C 310 carbocyclyl substituted with 0-5 R e, and -(CH 2) r -heterocyclyl substituted with 0-5 R e; or R a and R a together with the nitrogen atom to which they are both attached form a heterocyclic ring substituted with 0-5 R e; R b, at each occurrence, is independently selected from H, C 1-6 alkyl substituted with 0-5 R e, C 2-6 alkenyl substituted with 0-5 R e, C 2-6 alkynyl substituted with 0-5 R e, aryl substituted with 0-5 R e, and heterocyclyl substituted with 0-5 R e; R c, at each occurrence, is independently selected from C 1-6 alkyl substituted with 0-5 R e, C 3-6 carbocyclyl, and heterocyclyl; R e, at each occurrence, is independently selected from F, Cl, Br, CN, NO 2, =O, CO 2 H, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, and -(CH 2) r -C 3-6 cycloalkyl; p, at each occurrence, is independently selected from zero, 1, and 2; and r, at each occurrence, is independently selected from zero, 1, 2, 3, and 4.