A system for personalized printing, paper and paperboard processing, and binding, to enable automatic management of operations of paper and paperboard processing and binding, which is of a modular type and is configured so as manufacturing machines or processing stations (A2, A3, B, C, D, E, F, G) may be inserted into said system by allocating them therein according to the desired modalities, number, and operating sequence, for a personalizable printing, paper and paperboard processing, and binding, with the maximum flexibility of use and operation according to the needs at the moment of production; wherein said system is configured to operate in a completely automated mode and to be completely managed locally or remotely by means of an electronic processor equipped with purposely provided management software designed to manage and control the system itself, together with the individual various stations or machines (A2, A3, B, C, D, E, F, G) that make it up, wherein the system is substantially constituted by: at least one automatic sheet feeder of the stack or drive-belt type, designed to take up continuously or individually pre-printed sheets and to pre-position at least one sheet; at least one automatic sheet feeder of the drive-belt type, designed to pre-position the sheet with at least one object; at least one folding machine or folding-gluing machine, which is likewise provided with a working surface, a roller track, and free clamping members for the various devices, a programmer with touch screen, and a plurality of photoelectric cells at input and output, is prearranged for all the types of accessories, such as card applicators, and is designed for carrying out processing operations on a plurality of objects, such as cases, CDs, simple and multiple folders, boxes, possibly with bellows, CD covers and envelopes, mailers, two-dimensional or three-dimensional parcels, etc.; at least one machine designed to carry out particular processes/prints personalizable on customer's request; at least one sealing machine; at least one folding-and-inserting machine; at least one machine for applying labels and/or identification means, for example of an RFID type; and a plurality of further elements, accessories, apparatuses, useful for each specific production process, such as: helix folding assemblies complete with tractors, devices for creating the bellows, V-shaped folding pouches for paper or card with chrome-plated rollers with mobile rubber-coated sectors, freely positionable rods, built-in partial deflectors, automatic loaders for insertion of the products or objects, alignment brackets, tool-holders, outlet collectors, preferably of the shingling type, gluers, preferably with multi-outlet expansion, personalized-printing stations equipped with printing cartridges of various types, and industrial imager readers equipped with a plurality of photoelectric cells, characterized in that the system further comprises at least one video monitoring means equipped with means for acquisition of the images of the process. at least one automatic sheet feeder of the stack or drive-belt type, designed to take up continuously or individually pre-printed sheets and to pre-position at least one sheet; at least one automatic sheet feeder of the drive-belt type, designed to pre-position the sheet with at least one object; at least one folding machine or folding-gluing machine, which is likewise provided with a working surface, a roller track, and free clamping members for the various devices, a programmer with touch screen, and a plurality of photoelectric cells at input and output, is prearranged for all the types of accessories, such as card applicators, and is designed for carrying out processing operations on a plurality of objects, such as cases, CDs, simple and multiple folders, boxes, possibly with bellows, CD covers and envelopes, mailers, two-dimensional or three-dimensional parcels, etc.; at least one machine designed to carry out particular processes/prints personalizable on customer's request; at least one sealing machine; at least one folding-and-inserting machine; at least one machine for applying labels and/or identification means, for example of an RFID type; and a plurality of further elements, accessories, apparatuses, useful for each specific production process, such as: helix folding assemblies complete with tractors, devices for creating the bellows, V-shaped folding pouches for paper or card with chrome-plated rollers with mobile rubber-coated sectors, freely positionable rods, built-in partial deflectors, automatic loaders for insertion of the products or objects, alignment brackets, tool-holders, outlet collectors, preferably of the shingling type, gluers, preferably with multi-outlet expansion, personalized-printing stations equipped with printing cartridges of various types, and industrial imager readers equipped with a plurality of photoelectric cells,