mhurhangee/ep-ind-claims huggingface dataset:
A particle filter system for engines comprising a particle filter located in an exhaust line of an internal combustion engine, comprising a first pressure sensor arranged at the inlet of the particle filter and a second pressure sensor arranged at the outlet of the particle filter, for determining a pressure loss between the inlet and the outlet of the particle filter, characterized in that it further comprises: - a water injector located in the inlet region of the particle filter for injecting pressurized water towards said particle filter in a restructuring process for restructuring particles accumulated in said particle filter; - a conduit arranged between at least one water supply source and said injector; - an injection pump arranged in said conduit for increasing water pressure to an injection pressure; and - a control unit controlling the actuation of the injection pump depending on the pressure loss determined by the pressure sensors, wherein the restructuring of the particles accumulated in the monolith of the particle filter, caused by water injection, reduces the pressure loss of the particle filter without having to carry out the regeneration process, without reducing the trapped mass of particles and without reducing filtering efficiency and thereby delaying the application time of active regeneration techniques. - a water injector located in the inlet region of the particle filter for injecting pressurized water towards said particle filter in a restructuring process for restructuring particles accumulated in said particle filter; - a conduit arranged between at least one water supply source and said injector; - an injection pump arranged in said conduit for increasing water pressure to an injection pressure; and - a control unit controlling the actuation of the injection pump depending on the pressure loss determined by the pressure sensors, wherein the restructuring of the particles accumulated in the monolith of the particle filter, caused by water injection, reduces the pressure loss of the particle filter without having to carry out the regeneration process, without reducing the trapped mass of particles and without reducing filtering efficiency and thereby delaying the application time of active regeneration techniques.
A molecule having the following formula and N-oxides, agriculturally acceptable acid addition salts, salts, solvates, crystal polymorphs, isotopes, resolved stereoisomers, or tautomers of the molecule.
A method for connecting a tubular assembly, comprising the steps of: - forming a first tubular having a first inner diameter and a first wall thickness, said first tubular being comprised of a first connection end; - forming a second tubular having a second inner diameter and a second wall thickness, said second tubular being comprised of a second connection end; - increasing said first wall thickness of said first connection end, according to a first amount of increase in said first wall thickness; - increasing said first inner diameter of said first connection end to a first increased inner diameter (D1') according to said first amount (T1') of increase in said first wall thickness; - increasing said second wall thickness of said second connection end, according to a second amount (T2') of increase in said second wall thickness, so as to align with said first connection end; - increasing said second inner diameter of said second connection end to a second increased inner diameter (D2') according to said second amount (T2') of increase in said second wall thickness so as to align with said first connection end; - attaching said first tubular and said second tubular at a weld point between said first connection end and said second connection end so as to form a tubular connection assembly, wherein said first connection end with said first amount of increase (T1') in said first wall thickness and said first increased inner diameter (D1') and said second connection end with said second amount of increase (T2') in said second wall thickness and said second increased inner diameter (D2') increases fatigue performance of said weld point of said tubular connection assembly by a target amount greater than fatigue performance of a weld point between said first inner diameter and said first wall thickness and said second inner diameter and said second wall thickness. - forming a first tubular having a first inner diameter and a first wall thickness, said first tubular being comprised of a first connection end; - forming a second tubular having a second inner diameter and a second wall thickness, said second tubular being comprised of a second connection end; - increasing said first wall thickness of said first connection end, according to a first amount of increase in said first wall thickness; - increasing said first inner diameter of said first connection end to a first increased inner diameter (D1') according to said first amount (T1') of increase in said first wall thickness; - increasing said second wall thickness of said second connection end, according to a second amount (T2') of increase in said second wall thickness, so as to align with said first connection end; - increasing said second inner diameter of said second connection end to a second increased inner diameter (D2') according to said second amount (T2') of increase in said second wall thickness so as to align with said first connection end; - attaching said first tubular and said second tubular at a weld point between said first connection end and said second connection end so as to form a tubular connection assembly,
A pharmaceutical composition comprising i) an isolated protein comprising a variant activin IIB receptor polypeptide (vActRIIB) wherein vActRIIB comprises a polypeptide sequence having at least 95% identity to the amino acid sequence set forth at amino acids 25 through 134 of SEQ ID NO: 18, wherein the polypeptide comprises an amino acid substitution at position 28, and wherein the polypeptide is capable of binding myostatin, activin A, or GDF-11, and ii) a chemotherapeutic agent.
A sensing device adapted to be applied to an analyte molecule of a liquid sample and a buffer, comprising: at least one first inlet, for inputting the liquid sample; at least one second inlet, for inputting the buffer; a micro-flow channel, communicating with the first inlet and the second inlet; and at least one immobilization element adapted to immobilize a sensing molecule for the analyte molecule in the micro-flow channel, wherein the sensing molecule is capable of generating an association reaction with the analyte molecule of the liquid sample, and generating a dissociation reaction with the analyte molecule and the buffer in reverse direction, wherein the sensing molecule and the analyte molecule of the liquid sample are capable of generating the association reaction after the liquid sample flows into the micro-flow channel, wherein then the sensing molecule and the analyte molecule are capable of generating the dissociation reaction after the buffer flows reversely into the micro-flow channel, and wherein the micro-flow channel has two ends which are respectively connected to the first inlet and the second inlet, namely the micro-flow channel is between the first inlet and the second inlet. at least one first inlet, for inputting the liquid sample; at least one second inlet, for inputting the buffer; a micro-flow channel, communicating with the first inlet and the second inlet; and at least one immobilization element adapted to immobilize a sensing molecule for the analyte molecule in the micro-flow channel, wherein the sensing molecule is capable of generating an association reaction with the analyte molecule of the liquid sample, and generating a dissociation reaction with the analyte molecule and the buffer in reverse direction, wherein the sensing molecule and the analyte molecule of the liquid sample are capable of generating the association reaction after the liquid sample flows into the micro-flow channel, wherein then the sensing molecule and the analyte molecule are capable of generating the dissociation reaction after the buffer flows reversely into the micro-flow channel, and wherein the micro-flow channel has two ends which are respectively connected to the first inlet and the second inlet, namely the micro-flow channel is between the first inlet and the second inlet.
A device for multispectral optoacoustic imaging of an object, the device comprising a) an irradiation unit configured to irradiate the object with electromagnetic radiation at two or more different irradiation wavelengths (λ), said electromagnetic radiation having a time-varying intensity, b) a detection unit configured to detect acoustic waves generated in the object upon irradiating the object with the electromagnetic radiation at the different irradiation wavelengths (λ), and c) a processing unit configured to reconstruct images (P(r, λ)) of the object based on the detected acoustic waves generated in the object at each of the irradiation wavelengths (λ) and to determine a spatial distribution of at least one first concentration value (c' HbO2, c' HHb), which relates to a concentration of at least one electromagnetic radiation absorber (HbO 2, HHb) in the object, wherein the determination of the spatial distribution of the at least one first concentration value (c' HbO2, c' HHb) is based on - the reconstructed images (P(r, λ)) at the different irradiation wavelengths (λ), - at least one wavelength-dependent extinction coefficient (ε 1 (λ j), ε 2 (λ j)) of the at least one electromagnetic radiation absorber (HbO 2, HHb) in the object, and - a linear combination of at least two model spectra (Φ M (λ), Φ i (λ)), the model spectra (Φ M (λ), Φ i (λ)) representing wavelength-dependent basis functions of a radiation fluence (Φ(r,λ,)) or of a function (Φ'(r,λ)) of a radiation fluence (Φ(r,λ)), in particular a normalized radiation fluence (Φ(r,λ)/||Φ(r)||), in the object. a) an irradiation unit configured to irradiate the object with electromagnetic radiation at two or more different irradiation wavelengths (λ), said electromagnetic radiation having a time-varying intensity, b) a detection unit configured to detect acoustic waves generated in the object upon irradiating the object with the electromagnetic radiation at the different irradiation wavelengths (λ), and c) a processing unit configured - the reconstructed images (P(r, λ)) at the different irradiation wavelengths (λ), - at least one wavelength-dependent extinction coefficient (ε 1 (λ j), ε 2 (λ j)) of the at least one electromagnetic radiation absorber (HbO 2, HHb) in the object, and - a linear combination of at least two model spectra (Φ M (λ), Φ i (λ)), the model spectra (Φ M (λ), Φ i (λ)) representing wavelength-dependent basis functions of a radiation fluence (Φ(r,λ,)) or of a function (Φ'(r,λ)) of a radiation fluence (Φ(r,λ)), in particular a normalized radiation fluence (Φ(r,λ)/||Φ(r)||), in the object.
A camera module, comprising: a first camera module; a second camera module arranged side by side with the first camera module; a first flexible printed circuit connected to the first camera module; a second flexible printed circuit connected to the second camera module; wherein at least one of the first flexible printed circuit and the second flexible printed circuit extends along the arrangement direction of the first camera module and the second camera module, wherein the second camera module comprises a second camera, a light guide component, and a frame, the frame accommodates and fixes the second camera and the light guide component, and the light guide component is disposed between the first camera module and the second camera. a first camera module; a second camera module arranged side by side with the first camera module; a first flexible printed circuit connected to the first camera module; a second flexible printed circuit connected to the second camera module; wherein at least one of the first flexible printed circuit and the second flexible printed circuit extends along the arrangement direction of the first camera module and the second camera module, wherein the second camera module comprises a second camera, a light guide component, and a frame, the frame accommodates and fixes the second camera and the light guide component, and the light guide component is disposed between the first camera module and the second camera.
A method of making a medical device (10, 20, 30, 40) comprising the steps of: a) braiding a plurality of metal strands exhibiting a shape memory property into a tubular metal fabric; b) securing opposed ends of the fabric to inhibit unraveling thereof; c) inserting the fabric in or on a molding structure of a first predetermined shape configuration; d) heating the molding structure to an elevated temperature for a time sufficient to heat set the fabric in the first predetermined shape configuration when the medical device is in a relaxed state; and e) imparting a second predetermined shape configuration (10, 20, 30, 40) to the metal fabric when in said relaxed state, wherein the first predetermined shape configuration comprises a plurality of generally spherical or ovaloid members joined together in a string by intermediate articulating members. a) braiding a plurality of metal strands exhibiting a shape memory property into a tubular metal fabric; b) securing opposed ends of the fabric to inhibit unraveling thereof; c) inserting the fabric in or on a molding structure of a first predetermined shape configuration; d) heating the molding structure to an elevated temperature for a time sufficient to heat set the fabric in the first predetermined shape configuration when the medical device is in a relaxed state; and e) imparting a second predetermined shape configuration (10, 20, 30, 40) to the metal fabric when in said relaxed state,
A computer-implemented, parallel-processing method for simulating hydrocarbon migration in a subsurface medium, comprising: determining that hydrocarbon has been expelled in source rocks associated with a plurality of grid cells divided into one or more subdomains; identifying potential trap peaks within the plurality of grid cells; performing an invasion process until the hydrocarbon stops migrating within the plurality of grid cells; the method characterised by comprising the steps of: determining whether grid cells containing hydrocarbons contain an excess volume of hydrocarbons; if it is determined that an excess condition exists, performing an accumulation process to model filling of grid cells with the hydrocarbon at a trap or accumulation associated with the identified potential trap peaks until said excess condition does not exist; and updating (185, 110c) the trap with a hydrocarbon potential value. determining that hydrocarbon has been expelled in source rocks associated with a plurality of grid cells divided into one or more subdomains; identifying potential trap peaks within the plurality of grid cells; performing an invasion process until the hydrocarbon stops migrating within the plurality of grid cells; the method characterised by comprising the steps of: determining whether grid cells containing hydrocarbons contain an excess volume of hydrocarbons; if it is determined that an excess condition exists, performing an accumulation process to model filling of grid cells with the hydrocarbon at a trap or accumulation associated with the identified potential trap peaks until said excess condition does not exist; and updating (185, 110c) the trap with a hydrocarbon potential value.
A humanized immunoglobulin or antigen-binding fragment thereof having binding specificity for α4β7 integrin, for use in treating inflammatory bowel disease, said use comprising administering the immunoglobulin or antigen-binding fragment thereof in multiple doses, each of the doses independently comprising up to 8 mg immunoglobulin or antigen-binding fragment per kg body weight, wherein the minimum interval between any two doses is a period of at least 7 days and the minimum interval before a subsequent dose is administered is a period of one month when a dose comprises 8 mg immunoglobulin or fragment thereof per kg body weight, and wherein said immunoglobulin or antigen-binding fragment has binding specificity for the α4β7 complex wherein said humanized immunoglobulin or antigen-binding fragment thereof comprises three complementarity determining regions (CDR1, CDR2 and CDR3) of a light chain variable region and three complementarity determining regions (CDR1, CDR2 and CDR3) of a heavy chain variable region of the amino acid sequence set forth below: light chain: CDR1 SEQ ID NO:9 CDR2 SEQ ID NO:10 CDR3 SEQ ID NO:11 heavy chain: CDR1 SEQ ID NO:12 CDR2 SEQ ID NO:13 CDR3 SEQ ID NO:14, and wherein the immunoglobulin or fragment thereof is administered parenterally.
A mutual rotating scroll compressor comprising: a casing; a first frame fixed to the casing; a second frame provided with an interval between the first frame and the second frame, a compression space being provided between the first frame and the second frame; a first scroll rotatably supported by the first frame and coupled to a driving motor to rotate in the compression space; a second scroll engaged with the first scroll to rotate about the second frame, the second scroll and the first scroll forming a compression chamber in the compression space; and a bearing housing including a housing part, including a boss accommodation part to which the second scroll is rotatably coupled, characterized in that the bearing housing further includes a hinge lug which extends from the housing part and is movably coupled to the second frame, wherein in the bearing housing, a third center (O 3) which is a center of the hinge lug in an axial direction is provided on a plane and is eccentric with respect to a second center (O 2) which is a center of the boss accommodation part in an axial direction, and each of the second center (O 2) and the third center (O 3) is provided on a plane and are eccentric with respect to a first center (O 1) of the first scroll in an axial direction. a casing; a first frame fixed to the casing; a second frame provided with an interval between the first frame and the second frame, a compression space being provided between the first frame and the second frame; a first scroll rotatably supported by the first frame and coupled to a driving motor to rotate in the compression space; a second scroll engaged with the first scroll to rotate about the second frame, the second scroll and the first scroll forming a compression chamber in the compression space; and a bearing housing including a housing part, including a boss accommodation part to which the second scroll is rotatably coupled, characterized in that the bearing housing further includes a hinge lug which extends from the housing part and is movably coupled to the second frame, wherein in the bearing housing, a third center (O 3) which is a center of the hinge lug in an axial direction is provided on a plane and is eccentric with respect to a second center (O 2) which is a center of the boss accommodation part in an axial direction, and each of the second center (O 2) and the third center (O 3) is provided on a plane and are eccentric with respect to a first center (O 1) of the first scroll in an axial direction.
A system for autonomous stabilization of quantum states comprising: - a quantum harmonic oscillator configured to carry information encoded in states of the oscillator having a predetermined parity of a number of bosons comprised in the harmonic oscillator, - an auxiliary device configured to be in a ground state |g> or in an excited state |f> among a plurality of excited states, the device being dispersively coupled to the oscillator, so that a frequency difference between the ground state |g> and the excited state |f> depends linearly on a frequency shift χ and on the number of bosons, - a dissipator configured to switch from an excited state |1> to a ground state |0>, - an exciter configured to generate first (205, 405) and second (206, 406) frequency combs, intended to be sent to at least one of the quantum harmonic oscillator, the auxiliary device and the dissipator so as to add a boson in the harmonic oscillator if the number of bosons does not have the predetermined parity, characterized in that a first frequency difference separating two successive lines of the first frequency comb (205, 405) is equal to twice the frequency shift χ and is equal to twice a second frequency difference separating two successive lines of the second comb (206, 406), wherein the first and second combs have peaks in the time domain, the peaks of the first comb being time-shifted relative to the peaks of the second comb. - a quantum harmonic oscillator configured to carry information encoded in states of the oscillator having a predetermined parity of a number of bosons comprised in the harmonic oscillator, - an auxiliary device configured to be in a ground state |g> or in an excited state |f> among a plurality of excited states, the device being dispersively coupled to the oscillator, so that a frequency difference between the ground state |g> and the excited state |f> depends linearly on a frequency shift χ and on the number of bosons, - a dissipator configured to switch from an excited state |1> to a ground state |0>, - an exciter configured to generate first (205, 405) and second (206, 406) frequency combs, intended to be sent to at least one of the quantum harmonic oscillator, the auxiliary device and the dissipator so as to add a boson in the harmonic oscillator if the number of bosons does not have the predetermined parity, characterized in that a first frequency difference separating two successive lines of the first frequency comb (205, 405) is equal to twice the frequency shift χ and is equal to twice a second frequency difference separating two successive lines of the second comb (206, 406), wherein the first and second combs have peaks in the time domain, the peaks of the first comb being time-shifted relative to the peaks of the second comb.
A human shoe or device for insertion into a human shoe having a foot supporting upper surface, wherein the human shoe or device has a shallow channel on the foot supporting upper surface adapted to underlie the first metatarsal shaft in part, wherein the channel is adapted to extend in a direction from the toe end of the shoe heelward under the first metatarsal shaft, characterized in that the channel is pitched or rotated 4 ± 1 degrees plantargrade, with a toeward end of the channel lower than the heelward end of the channel, and wherein the channel is rolled or sloped in a lateral to medial direction downward 9 ± 2 degrees, in the frontal plane, and wherein the channel is yawed or rotated 10 ± 5 degrees clockwise relative to a superior view of the transverse plane, for the left foot shoe, and yawed or rotated 10 ± 5 degrees counterclockwise relative to a superior view of the transverse plane for the right foot shoe, and wherein the shoe or device is contoured and has a dome or raised area configured to underlie between the first and second metatarsal shafts rearward of the first and second metatarsal heads of the wearer.
A GCC ligand conjugated to an active agent for use in treating primary and/or metastatic stomach or esophageal cancer, wherein the GCC ligand is a peptide less than 25 amino acids in length, and wherein the active agent is selected from the group consisting of: an active enzyme, a chemotherapeutic, a toxin, a radiotherapeutic, and a radiosensitising agent.