A method performed by a first network node in a wireless network, for establishment of a neighbour relation with a second network node in the wireless network, wherein the first network node and the second network node perform radio communication with wireless devices, the method comprising: - obtaining (200, 1:1), from a control node, a set of reference signals reserved for neighbour relation establishment, wherein the neighbour relation is a direct connection between network nodes, - receiving (204, 1:4), from a wireless device served by the first network node, a measurement report indicating at least one detected reference signal that is recognized by the first network node as belonging to the set of reserved reference signals, - identifying (206, 1:5) the second network node based on the at least one detected reserved reference signal indicated in the received measurement report, wherein identifying the second network node comprises: i) sending an identification request to the control node based on the at least one detected reference signal indicated in the received measurement report, and obtaining, from the control node, an identity of the second network node, or ii) identifying the second network node from an IP address or global identity of the second network node indicated in an allocation message received from the control node, after receiving the set of reference signals reserved for neighbour relation establishment, and wherein the allocation message indicates one or more reference signals allocated to the second network node from the set of reserved reference signals; and - establishing (208, 1:6) a neighbour relation with the second network node. - obtaining (200, 1:1), from a control node, a set of reference signals reserved for neighbour relation establishment, wherein the neighbour relation is a direct connection between network nodes, - receiving (204, 1:4), from a wireless device served by the first network node, a measurement report indicating at least one detected reference signal that is recognized by the first network node as belonging to the set of reserved reference signals, - identifying (206, 1:5) the second network node based on the at least one detected reserved reference signal indicated in the received measurement report, wherein identifying the second network node comprises: i) sending an identification request to the control node based on the at least one detected reference signal indicated in the received measurement report, and obtaining, from the control node, an identity of the second network node, or ii) identifying the second network node from an IP address or global identity of the second network node indicated in an allocation message received from the control node, after receiving the set of reference signals reserved for neighbour relation establishment, and wherein the allocation message indicates one or more reference signals allocated to the second network node from the set of reserved reference signals; and i) sending an identification request to the control node based on the at least one detected reference signal indicated in the received measurement report, and obtaining, from the control node, an identity of the second network node, or ii) identifying the second network node from an IP address or global identity of the second network node indicated in an allocation message received from the control node, after receiving the set of reference signals reserved for neighbour relation establishment, and wherein the allocation message indicates one or more reference signals allocated to the second network node from the set of reserved reference signals; and - establishing (208, 1:6) a neighbour relation with the second network node.