mhurhangee/ep-ind-claims huggingface dataset:
A method of making a genetically-modified immunodeficient mouse comprising exogenous hepatocytes, the method comprising: administering to an immunodeficient genetically-modified mouse a molecular anti-hepatocyte agent, wherein the molecular anti-hepatocyte agent is monocrotaline or anti-mouse CD95 antibody, wherein the immunodeficient mouse expresses a PiZ variant Glu342Lys of human α-1 antitrypsin (Z-AAT); and administering to the immunodeficient mouse human hepatocytes; wherein the molecular anti-hepatocyte agent is administered to the immunodeficient mouse prior to administration of the human hepatocytes; and wherein the method does not include performing a surgical hepatectomy. administering to an immunodeficient genetically-modified mouse a molecular anti-hepatocyte agent, wherein the molecular anti-hepatocyte agent is monocrotaline or anti-mouse CD95 antibody, wherein the immunodeficient mouse expresses a PiZ variant Glu342Lys of human α-1 antitrypsin (Z-AAT); and administering to the immunodeficient mouse human hepatocytes; wherein the molecular anti-hepatocyte agent is administered to the immunodeficient mouse prior to administration of the human hepatocytes; and wherein the method does not include performing a surgical hepatectomy.
A pool cleaner comprising: a housing; a driving motor that is configured to assist in moving the pool cleaner; a filtering element that is at least partially surrounded by the housing; an intake aperture; a first fluid conduit; and a first grille (110, 250); wherein the filtering element is configured to filter fluid from the intake aperture to provide filtered fluid; wherein the first fluid conduit is configured to direct the filtered fluid towards the first grille; and wherein the pool cleaner is characterized by having the first grill comprise two or more movable first panes (253, 254, 272); and wherein the first grille is configured to output the filtered fluid at a first direction that is responsive to a position of the two or more movable panes. a housing; a driving motor that is configured to assist in moving the pool cleaner; a filtering element that is at least partially surrounded by the housing; an intake aperture; a first fluid conduit; and a first grille (110, 250); wherein the filtering element is configured to filter fluid from the intake aperture to provide filtered fluid; wherein the first fluid conduit is configured to direct the filtered fluid towards the first grille; and wherein the pool cleaner is characterized by having the first grill comprise two or more movable first panes (253, 254, 272); and wherein the first grille is configured to output the filtered fluid at a first direction that is responsive to a position of the two or more movable panes.
An optical sight comprising: a housing having a main body, a pair of upwardly extending posts, and a cross member extending between the pair of upwardly extending posts; an optical element supported by the housing, the optical element being positioned between the pair of upwardly extending posts and between the main body and the cross member; and a photo detector positioned in the housing, the photo detector being configured to detect ambient light at a target object, wherein a first post of the pair of upwardly extending posts and the cross member are joined at a shoulder of the housing, characterized in that the photo detector is positioned in the shoulder of the housing. a housing having a main body, a pair of upwardly extending posts, and a cross member extending between the pair of upwardly extending posts; an optical element supported by the housing, the optical element being positioned between the pair of upwardly extending posts and between the main body and the cross member; and a photo detector positioned in the housing, the photo detector being configured to detect ambient light at a target object, wherein a first post of the pair of upwardly extending posts and the cross member are joined at a shoulder of the housing, characterized in that the photo detector is positioned in the shoulder of the housing.
A valve arrangement for supplying air to an internal combustion engine, said valve arrangement comprising: a first valve for controlling an air supply to a cylinder, said first valve being movable between a closed position in which said air cannot be supplied to said cylinder and an open position in which said air is supplied to said cylinder, said first valve comprising: a first valve head, and a first valve stem comprising an inlet in a side wall of said valve stem, wherein said inlet is configured to receive additional air from a feeder channel, said first valve stem further comprising an internal passage, arranged in the length direction of said valve stem and fluidly connected to said inlet and configured to supply said additional air to said cylinder; a second valve arranged within said first valve and configured to control the flow of additional air to said cylinder, said second valve comprising a second valve stem and a second valve head in contact with an inner surface of said first valve head when said second valve is in a closed position; a tubular valve guide arranged to surround a portion of said first valve stem such that said first valve stem is movable in said valve guide; characterized in that said valve guide comprises an inner groove forming a cavity between said valve guide and said first valve stem, wherein said valve guide further comprises a valve guide aperture configured to fluidly connect said inner groove to said feeder channel, and wherein said inlet of said first valve stem is aligned with said valve guide aperture when said first valve is in a closed position. a first valve for controlling an air supply to a cylinder, said first valve being movable between a closed position in which said air cannot be supplied to said cylinder and an open position in which said air is supplied to said cylinder, said first valve comprising: a first valve head, and a first valve stem comprising an inlet in a side wall of said valve stem, wherein said inlet is configured to receive additional air from a feeder channel, said first valve stem further comprising an internal passage, arranged in the length direction of said valve stem and fluidly connected to said inlet and configured to supply said additional air to said cylinder; a second valve arranged within said first valve and configured to control the flow of additional air to said cylinder, said second valve comprising a second valve stem and a second valve head in contact with an inner surface of said first valve head when said second valve is in a closed position; a tubular valve guide arranged to surround a portion of said first valve stem such that said first valve stem is movable in said valve guide; characterized in that said valve guide comprises an inner groove forming a cavity between said valve guide and said first valve stem, wherein said valve guide further comprises a valve guide aperture configured to fluidly connect said inner groove to said feeder channel, and wherein said inlet of said first valve stem is aligned with said valve guide aperture when said first valve is in a closed position.
A method of fabricating an antimicrobial surface coating, comprising: providing a substrate having a substrate surface; providing at least one first antimicrobial material in at least one first pattern on said substrate surface; and providing at least one second antimicrobial material on said substrate surface in at least one second pattern disposed in generally adjacent relationship with respect to said at least one first pattern of said first antimicrobial material; wherein said providing at least one second antimicrobial material on said substrate surface comprises providing at least one second antimicrobial material on said substrate surface at a spacing of from 1 micron to 1 millimeter with respect to said at least one first antimicrobial material. providing a substrate having a substrate surface; providing at least one first antimicrobial material in at least one first pattern on said substrate surface; and providing at least one second antimicrobial material on said substrate surface in at least one second pattern disposed in generally adjacent relationship with respect to said at least one first pattern of said first antimicrobial material; wherein said providing at least one second antimicrobial material on said substrate surface comprises providing at least one second antimicrobial material on said substrate surface at a spacing of from 1 micron to 1 millimeter with respect to said at least one first antimicrobial material.
Method of enzymatic extraction of oils, proteins and fermentable sugars from vegetable material in aqueous medium, comprising the following steps: a) adding water to a vegetable material having a suitable particle size, b) adding an enzyme mixture containing at least one cellulase, at least one hemicellulase and at least one pectinase, the ratio between the pectinase activity and the cellulase activity being comprised between 0.3 and 2.5, and more preferably between 0.35 and 0.45, and the ratio between the pectinase activity and the hemicellulase activity being comprised between 1.10 -2 and 0.5, and more preferably between 1.10 -2 and 2.10 -2, the pectinase activity being less than 120 μmol/min/ml, and preferably less than 100 μmol/min/ml, wherein the amount of the enzyme mixture is comprised between 0.25% and 10% by volume of the water/vegetable material mixture, preferably between 1% and 6%, c) incubating with stirring the vegetable material and the enzyme mixture in order to release in the reaction medium oils, proteins and fermentable sugars, for a duration depending on the sought yields, d) separating the reaction medium in order to obtain free oil, an aqueous phase containing proteins and fermentable sugars, and a solid phase, e) optionally separating an emulsion of the free oil or of the aqueous phase, and recycling the emulsion in the reaction medium, f) separating the proteins and fermentable sugars from the aqueous phase. a) adding water to a vegetable material having a suitable particle size, b) adding an enzyme mixture containing at least one cellulase, at least one hemicellulase and at least one pectinase, the ratio between the pectinase activity and the cellulase activity being comprised between 0.3 and 2.5, and more preferably between 0.35 and 0.45, and the ratio between the pectinase activity and the hemicellulase activity being comprised between 1.10 -2 and 0.5, and more preferably between 1.10 -2 and 2.10 -2, the pectinase activity being less than 120 μmol/min/ml, and preferably less than 100 μmol/min/ml, wherein the amount of the enzyme mixture is comprised between 0.25% and 10% by volume of the water/vegetable material mixture, preferably between 1% and 6%, c) incubating with stirring the vegetable material and the enzyme mixture in order to release in the reaction medium oils, proteins and fermentable sugars, for a duration depending on the sought yields, d) separating the reaction medium in order to obtain free oil, an aqueous phase containing proteins and fermentable sugars, and a solid phase, e) optionally separating an emulsion of the free oil or of the aqueous phase, and recycling the emulsion in the reaction medium, f) separating the proteins and fermentable sugars from the aqueous phase.
Propulsion assembly comprising an aircraft engine suspended below a pylon of the aircraft by means of engine attachments comprising, at the front, a front engine attachment, at the rear, a rear engine attachment, and between the two engine attachments, a thrust force uptake device, a vertical median plane passing through a longitudinal axis of the engine separating the propulsion assembly into two parts, left and right, the thrust force uptake device comprising a main fitting fixed below the pylon and two links (101, 102), which are arranged on either side of the vertical median plane and each have a front end (101b, 102b) articulated to the engine and a rear end (101a, 102a) articulated to the main fitting by way of a spreader mounted so as to pivot on the main fitting about an axis of rotation that, on the one hand, is orthogonal to a mean plane for transmission of the thrust forces parallel to the longitudinal axis (T1, T2) of each of the two links and, on the other hand, is arranged in the vertical median plane, the longitudinal axes (T1, T2) of the two links (101, 102) being convergent in a direction from the front to the rear of the propulsion assembly, a first link being articulated to the spreader by means of a first connecting pin extending parallel to the mean plane for transmission of the thrust forces and perpendicular to the longitudinal axis of the first link, and a second link being articulated to the spreader by means of a second connecting pin extending parallel to the mean plane for transmission of the thrust forces and perpendicular to the longitudinal axis of the second link, characterized in that the spreader comprises two fastening tabs (125, 126) for fastening the links to the spreader, with a first fastening tab associated with the first link and a second fastening tab associated with the second link, wherein each fastening tab (125, 126) associated with a link (101, 102) extends parallel to the longitudinal axis (T1, T2) of said link (101, 102).
A method for removing CO 2, the method comprising bringing a CO 2 -facilitated transport membrane into contact with a gas containing CO 2 and H 2 at 100°C or higher thereby removing the CO 2 from the gas, wherein the CO 2 -facilitated transport membrane is formed such that a gel layer is supported by a hydrophilic porous membrane, and the gel layer is formed from a gel membrane containing moisture, which contains an additive of cesium carbonate or cesium bicarbonate or cesium hydroxide as a CO 2 carrier, the gel membrane containing moisture is a polyvinyl alcohol-polyacrylic acid copolymer gel membrane, and the gel layer is formed such that a weight ratio of cesium carbonate as a CO 2 carrier relative to a total weight of the polyvinyl alcohol-polyacrylic acid copolymer gel membrane and cesium carbonate is 65% by weight or more and 85% by weight or less.
A concentrate comprising: 0.01% to 10% quillaja; 15% to 70% non-aqueous solvent selected from the group consisting of propylene glycol, glycerol, ethanol, triacetin, ethyl acetate, benzyl alcohol, vegetable oil, 1,3-propanediol, and combinations thereof; and 2% to 60% acidulant selected from the group consisting of citric acid, malic acid, succinic acid, acetic acid, adipic acid, tartaric acid, fumaric acid, phosphoric acid, lactic acid, salts thereof, and combinations thereof; 0.1% to 20% lipid selected from the group consisting of castor oil, terpene hydrocarbons, flavor oils (consisting of one or more of the following derivatives: ketones, aldehydes, lactones, ethers, esters, sulfur compounds, furanones, terpenoids), oil soluble vitamins, nutraceuticals, fatty acids, poly-unsaturated fatty acids, triglycerides and triglyceride derivatives, antioxidants, colorants, vegetable oils, and combinations thereof; and 1% to 70% water; wherein a ratio of the water to the non-aqueous solvent in the concentrate is from 6:1 to 1:6 and a ratio of the water to the acidulant in the concentrate is from 60:1 to 1:10; and wherein the concentrate contains an oil-in-water emulsion having a pH of 2.0 to 2.6 and is shelf-stable at storage temperatures of 20°C to 25°C for at least 4 months. 0.01% to 10% quillaja; 15% to 70% non-aqueous solvent selected from the group consisting of propylene glycol, glycerol, ethanol, triacetin, ethyl acetate, benzyl alcohol, vegetable oil, 1,3-propanediol, and combinations thereof; and 2% to 60% acidulant selected from the group consisting of citric acid, malic acid, succinic acid, acetic acid, adipic acid, tartaric acid, fumaric acid, phosphoric acid, lactic acid, salts thereof, and combinations thereof; 0.1% to 20% lipid selected from the group consisting of castor oil, terpene hydrocarbons, flavor oils (consisting of one or more of the following derivatives: ketones, aldehydes, lactones, ethers, esters, sulfur compounds, furanones, terpenoids), oil soluble vitamins, nutraceuticals, fatty acids, poly-unsaturated fatty acids, triglycerides and triglyceride derivatives, antioxidants, colorants, vegetable oils, and combinations thereof; and 1% to 70% water; wherein a ratio of the water to the non-aqueous solvent in the concentrate is from 6:1 to 1:6 and a ratio of the water to the acidulant in the concentrate is from 60:1 to 1:10; and wherein the concentrate contains an oil-in-water emulsion having a pH of 2.0 to 2.6 and is shelf-stable at storage temperatures of 20°C to 25°C for at least 4 months.
A remote handling tool to limit contamination of a user of the tool or of a surface by the user of the tool, comprising: a tube forming a handle for the user, a hook which is movable respect to the tube between a retracted position in which the hook is inside the tube and an extended position in which the hook is located outside the tube and in which the hook is configured to handle an object in a first handling position, the tube being configured to be inserted about a grip for the user to actuate the grip by means of the handle formed by the tube, which tool is characterised: - in that it further includes a guide means (22, 53) for the hook, the guide means (22, 53) for the hook being configured to guide movement of the hook relative to the tube between the retracted position and the extended position without contact of the user with the hook and with the inside of the tube; and - in that the insertion of the tube about said grip is performed in a second handling position of the tool in which the hook is in the retracted position. a tube forming a handle for the user, a hook which is movable respect to the tube between a retracted position in which the hook is inside the tube and an extended position in which the hook is located outside the tube and in which the hook is configured to handle an object in a first handling position, the tube being configured to be inserted about a grip for the user to actuate the grip by means of the handle formed by the tube, which tool is characterised: - in that it further includes a guide means (22, 53) for the hook, the guide means (22, 53) for the hook being configured to guide movement of the hook relative to the tube between the retracted position and the extended position without contact of the user with the hook and with the inside of the tube; and - in that the insertion of the tube about said grip is performed in a second handling position of the tool in which the hook is in the retracted position. - in that it further includes a guide means (22, 53) for the hook, the guide means (22, 53) for the hook being configured to guide movement of the hook relative to the tube between the retracted position and the extended position without contact of the user with the hook and with the inside of the tube; and - in that the insertion of the tube about said grip is performed in a second handling position of the tool in which the hook is in the retracted position.
A monoclonal anti-HIV antibody comprising: a heavy chain sequence comprising the amino acid sequence of SEQ ID NO: 420 and a light chain sequence comprising the amino acid sequence of SEQ ID NO: 429.
A positive active material for a lithium secondary battery comprising a) a lithium metal complex oxide described by the following Formula 1 as core particles; and b) a glass phase overlayer of a non-crystalline oxide described by the following Formula 2, which is coated on the a) lithium metal complex oxide as core particles and is sintered, wherein the glass phase overlayer comprises D z O w as a network structure maker which makes the glass phase strong, and C s O t as a network structure modifier which makes the glass phase weak: [Formula 1] LiA 1-x B x O 2 wherein, A is Co or Ni; B is selected from the group consisting of Al, B, Ni, Co, Ti, Sn, Mn, and Zr; and x is a real number of 0 to 0.5, [Formula 2] C s O t ·yD z O w wherein, C is selected from the group consisting of Na, K, Mg, Ba, Sr, Y, Sn, Ga, In, Th, Pb, Li, Zn, Ca, Cd, Rb, Sc, Ti, Zn, Be, and Zr; D is selected from the group consisting of Al, B, Si, Ge, V, As, Sb, Zr, Nb, Ti, Zn, Zr, and Pb;. y is a real number of 0.5 to 3; and s and t, and z and w, are respectively with respect to an oxidation number of C and D, wherein the overlayer of b) is 0.01 to 10 mol % of the lithium metal complex oxide of a). a) a lithium metal complex oxide described by the following Formula 1 as core particles; and b) a glass phase overlayer of a non-crystalline oxide described by the following Formula 2, which is coated on the a) lithium metal complex oxide as core particles and is sintered, wherein the glass phase overlayer comprises D z O w as a network structure maker which makes the glass phase strong, and C s O t as a network structure modifier which makes the glass phase weak: [Formula 1] LiA 1-x B x O 2 wherein, A is Co or Ni; B is selected from the group consisting of Al, B, Ni, Co, Ti, Sn, Mn, and Zr; and x is a real number of 0 to 0.5, [Formula 2] C s O t ·yD z O w wherein, C is selected from the group consisting of Na, K, Mg, Ba, Sr, Y, Sn, Ga, In, Th, Pb, Li, Zn, Ca, Cd, Rb, Sc, Ti, Zn, Be, and Zr; D is selected from the group consisting of Al, B, Si, Ge, V, As, Sb, Zr, Nb, Ti, Zn, Zr, and Pb;. y is a real number of 0.5 to 3; and s and t, and z and w, are respectively with respect to an oxidation number of C and D, wherein the overlayer of b) is 0.01 to 10 mol % of the lithium metal complex oxide of a). A is Co or Ni; B is selected from the group consisting of Al, B, Ni, Co, Ti, Sn, Mn, and Zr; and x is a real number of 0 to 0.5, C is selected from the group consisting of Na, K, Mg, Ba, Sr, Y, Sn, Ga, In, Th, Pb, Li, Zn, Ca, Cd, Rb, Sc, Ti, Zn, Be, and Zr; D is selected from the group consisting of Al, B, Si, Ge, V, As, Sb, Zr, Nb, Ti, Zn, Zr, and Pb;. y is a real number of 0.5 to 3; and s and t, and z and w, are respectively with respect to an oxidation number of C and D, wherein the overlayer of b) is 0.01 to 10 mol % of the lithium metal complex oxide of a).
A Factor VII or Factor FVIIa glycoprotein having an N-linked glycosylation pattern comprising glycans; wherein the glycosylation pattern comprises: substantially no glycans with terminal N-acetylneuraminic acid and a substantial glycan that is a glycan of formula I: (GlcNAc) 4 (Man) 3 (Gal) 2 (Fuc) and trace amounts or less of one or more glycans selected from the group consisting of a glycan of formula II: (GlcNAc) 5 (Man) 3 (Gal)(Fuc) and a glycan of formula III: (GlcNAc) 6 (Man) 3 (Fuc) and; a glycan of formula V: (GlcNAc) 6 (Gal) 4 (Man) 3 (Fuc). substantially no glycans with terminal N-acetylneuraminic acid and a substantial glycan that is a glycan of formula I: (GlcNAc) 4 (Man) 3 (Gal) 2 (Fuc) and trace amounts or less of one or more glycans selected from the group consisting of a glycan of formula II: (GlcNAc) 5 (Man) 3 (Gal)(Fuc) and a glycan of formula III: (GlcNAc) 6 (Man) 3 (Fuc) and; a glycan of formula V: (GlcNAc) 6 (Gal) 4 (Man) 3 (Fuc).