mhurhangee/ep-ind-claims huggingface dataset:
Quinazoline derivatives represented by the following structural general formula or their pharmaceutically acceptable salts or solvates thereof: wherein R 1 represents A is O, or S, R 2 is R 3 and R 4 are independently chosen from H, C 1-10 alkyl, C 2-10 alkenyl, C 2-10 alkynyl, C 3-10 cycloalkyl, C 1-10 alkyl with substituents, C 2-10 alkenyl with substituents, C 3-10 cycloalkyl with substituents, C 3-10 cycloalkenyl with substituents, C 1-10 ether or wherein said substituents are one or more groups chosen from nitro, amino, carboxy, halogen atoms, hydroxy, mercapto, C 1-6 alkoxy, ester group, C 1-6 alkoxycarbonyl, C 1-6 alkanoyloxy, aminocarbonyl, C 1-6 alkylaminocarbonyl, di(C1-6 alkyl)aminocarbonyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted aryl C 1-6 alkyl, optionally substituted heteroaryl C 1-6 alkyl, optionally substituted aryloxy, optionally substituted heteroaryloxy, optionally substituted aryl C 1-6 alkoxy, optionally substituted heteroaryl C 1-6 alkoxy, wherein said substituent on the aryl or heteroaryl group is one or more group chosen from hydroxy, mercapto, amino, nitro, halogen, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 alkylthio, carboxy. R 1 represents A is O, or S, R 2 is R 3 and R 4 are independently chosen from H, C 1-10 alkyl, C 2-10 alkenyl, C 2-10 alkynyl, C 3-10 cycloalkyl, C 1-10 alkyl with substituents, C 2-10 alkenyl with substituents, C 3-10 cycloalkyl with substituents, C 3-10 cycloalkenyl with substituents, C 1-10 ether or wherein said substituents are one or more groups chosen from nitro, amino, carboxy, halogen atoms, hydroxy, mercapto, C 1-6 alkoxy, ester group, C 1-6 alkoxycarbonyl, C 1-6 alkanoyloxy, aminocarbonyl, C 1-6 alkylaminocarbonyl, di(C1-6 alkyl)aminocarbonyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted aryl C 1-6 alkyl, optionally substituted heteroaryl C 1-6 alkyl, optionally substituted aryloxy, optionally substituted heteroaryloxy, optionally substituted aryl C 1-6 alkoxy, optionally substituted heteroaryl C 1-6 alkoxy, wherein said substituent on the aryl or heteroaryl group is one or more group chosen from hydroxy, mercapto, amino, nitro, halogen, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 alkylthio, carboxy.
A method for detecting and/or characterizing a ligand-target binding based on photochemically induced dynamic nuclear polarization (photo-CIDNP) enhanced NMR spectroscopy, the method comprising the following steps: (i) providing a sample comprising a photosensitizer and a ligand, wherein the photosensitizer is suitable for chemically inducing dynamic nuclear polarization of the ligand upon irradiation of the sample; (ii) irradiating sample at a wavelength and duration suitable for exciting the photosensitizer and under conditions allowing for chemically induced dynamic nuclear polarization of the ligand by the photosensitizer; (iii) recording an NMR spectrum of sample; (iv) providing a sample comprising sample and further comprising a target of interest; (v) irradiating sample under the conditions of step (ii); (vi) recording an NMR spectrum of sample; and (vii) comparing the NMR spectra of steps (iii) and (vi) and detecting and/or characterizing a ligand-target binding based on at least one difference in the NMR spectra of steps (iii) and (vi). (i) providing a sample comprising a photosensitizer and a ligand, wherein the photosensitizer is suitable for chemically inducing dynamic nuclear polarization of the ligand upon irradiation of the sample; (ii) irradiating sample at a wavelength and duration suitable for exciting the photosensitizer and under conditions allowing for chemically induced dynamic nuclear polarization of the ligand by the photosensitizer; (iii) recording an NMR spectrum of sample; (iv) providing a sample comprising sample and further comprising a target of interest; (v) irradiating sample under the conditions of step (ii); (vi) recording an NMR spectrum of sample; and (vii) comparing the NMR spectra of steps (iii) and (vi) and detecting and/or characterizing a ligand-target binding based on at least one difference in the NMR spectra of steps (iii) and (vi).
Use of a layered silicate mineral having an interlayer charge of 0 or an interlayer charge of from greater than 0 to not more than 0.6 for removing organic mercury contained in a hydrocarbon oil from the hydrocarbon oil, wherein organic mercury refers to a mercury compound wherein an alkyl group and mercury bond.
A magnetic inductive type position sensor, the position sensor comprising: a first rotor and a second rotor adapted to be coupled to a rotation shaft to rotate in association with rotation of the rotation shaft and having a plurality of protrusively and circumferentially formed wing members (21, 31), the first rotor and the second rotor having a different number of wing members (21, 31); a printed circuit board arranged between the first rotor and the second rotor; and a cover member supporting the printed circuit board; characterized in that the position sensor comprises a guide member (22, 32) connecting each distal end of the wing members (21, 31) to guide each of the wing members (21, 31) to be aligned on the same planar surface. a first rotor and a second rotor adapted to be coupled to a rotation shaft to rotate in association with rotation of the rotation shaft and having a plurality of protrusively and circumferentially formed wing members (21, 31), the first rotor and the second rotor having a different number of wing members (21, 31); a printed circuit board arranged between the first rotor and the second rotor; and a cover member supporting the printed circuit board; characterized in that the position sensor comprises a guide member (22, 32) connecting each distal end of the wing members (21, 31) to guide each of the wing members (21, 31) to be aligned on the same planar surface.
A camshaft assembly for an internal combustion piston engine comprising a first end part (16.1) and a second end part (16.2) and between the first end part (16.1) and the second end part (16.2) an intermediate part in which cams of the camshaft assembly are provided, which end parts (16.1,16.2) are provided with a bearing surface such that the camshaft assembly can be assembled to the engine rotatably supported by bearings via the bearing surfaces, and wherein the camshaft assembly has an direction of longitudinal axis, wherein at least one of the cams of the intermediate part comprise a first cam surface and a second cam surface substantially next to each other in the direction of the longitudinal axis, characterized in that the intermediate part is releasably assembled to the first end part (16.1) and to the second end part (16.2).
A biopsy kit comprising: biopsy tissue handling device, comprising: a first well, a second well, and a third well, each well having a bottom, a side wall, and an upward facing opening; and a channel network; the first well being in fluid communication with the second well and the third well through the channel network, wherein the channel network comprises a first channel, the first channel having a first end and a second end, the first end being connected to the first well, and characterized in that the first channel comprises one or more transverse grooves in fluid communication with and disposed at an angle relative to the first channel, the one or more transverse grooves each being configured to accommodate a cutting tool therein. a first well, a second well, and a third well, each well having a bottom, a side wall, and an upward facing opening; and a channel network; the first well being in fluid communication with the second well and the third well through the channel network, wherein the channel network comprises a first channel, the first channel having a first end and a second end, the first end being connected to the first well, and characterized in that the first channel comprises one or more transverse grooves in fluid communication with and disposed at an angle relative to the first channel, the one or more transverse grooves each being configured to accommodate a cutting tool therein.
A fuser unit for an image forming apparatus, the fuser unit comprising: a detecting unit to detect movement of the fuser unit and power supplied to the fuser unit; a controller unit to cut off the power supplied to the fuser unit according to the detected movement and power, and a fuser drive motor portion to drive the fuser unit, wherein the detecting unit comprises a power detecting portion to detect power that is supplied to the fuser unit, characterised in that: a motor in the fuser drive motor portion is a Brushless DC (BLDC) motor, the fuser drive motor portion is configured to output a motor rotation signal when the fuser unit is driven, wherein the motor rotation signal is a signal generated from a Hall sensor, and the controller unit comprises a power cutoff portion to cut off the power supplied to the fuser unit when the motor rotation signal is not output from the fuser drive motor portion and the power detecting portion detects the power that is supplied to the fuser unit. a detecting unit to detect movement of the fuser unit and power supplied to the fuser unit; a controller unit to cut off the power supplied to the fuser unit according to the detected movement and power, and a fuser drive motor portion to drive the fuser unit, wherein the detecting unit comprises a power detecting portion to detect power that is supplied to the fuser unit, characterised in that: a motor in the fuser drive motor portion is a Brushless DC (BLDC) motor, the fuser drive motor portion is configured to output a motor rotation signal when the fuser unit is driven, wherein the motor rotation signal is a signal generated from a Hall sensor, and the controller unit comprises a power cutoff portion to cut off the power supplied to the fuser unit when the motor rotation signal is not output from the fuser drive motor portion and the power detecting portion detects the power that is supplied to the fuser unit. a motor in the fuser drive motor portion is a Brushless DC (BLDC) motor, the fuser drive motor portion is configured to output a motor rotation signal when the fuser unit is driven, wherein the motor rotation signal is a signal generated from a Hall sensor, and the controller unit comprises a power cutoff portion to cut off the power supplied to the fuser unit when the motor rotation signal is not output from the fuser drive motor portion and the power detecting portion detects the power that is supplied to the fuser unit.
A device (1; 2) for randomly selecting a symbol among a plurality of pre-determined symbols, said device (1; 2) for randomly selection comprises a main body (11; 21) having a polyhedral shape provided with a plurality of sides in even number and in pairs parallel and opposite to each other, wherein each of said sides is able to be placed on a plane by placing the corresponding parallel and opposite side in a position parallel to, and spaced from, said plane; said device (1; 2) for randomly selection comprises a plurality of containment compartments (12; 22) equal to the number of said sides, wherein each of said containment compartment (12; 22) is made at one of said sides within said main body (11; 21) and is provided with a transparent cover at said side and a support base, opposite said transparent cover within said main body (11; 21), wherein said device (1; 2) for randomly selection further comprises a plurality of secondary devices for randomly selection, each arranged within one of said containment compartments (12; 22), said device (1; 2) for randomly selecting is characterized in that each of said secondary devices for randomly selection comprises a secondary body having a polyhedral shape provided with a plurality of faces in even number and in pairs parallel and opposite to each other, wherein each face is provided with one of the pre-determined graphic symbols, wherein each of said secondary devices for randomly selection has such a size as to be moved within said containment compartment (12; 22), and wherein each of said faces of said secondary device for randomly selection is able to be placed onto said support base by arranging only one face, corresponding to said face parallel and opposite to said support base, parallel to said support base and at said transparent cover. said device (1; 2) for randomly selection comprises a plurality of containment compartments (12; 22) equal to the number of said sides, wherein each of said containment compartment (12; 22) is made at one of said sides within said main body (11; 21) and is provided with a transparent cover at said side and a support base, opposite said transparent cover within said main body (11; 21), wherein said device (1; 2) for randomly selection further comprises a plurality of secondary devices for randomly selection, each arranged within one of said containment compartments (12; 22), said device (1; 2) for randomly selecting is characterized in that each of said secondary devices for randomly selection comprises a secondary body having a polyhedral shape provided with a plurality of faces in even number and in pairs parallel and opposite to each other, wherein each face is provided with one of the pre-determined graphic symbols, wherein each of said secondary devices for randomly selection has such a size as to be moved within said containment compartment (12; 22), and wherein each of said faces of said secondary device for randomly selection is able to be placed onto said support base by arranging only one face, corresponding to said face parallel and opposite to said support base, parallel to said support base and at said transparent cover.
An extreme ultraviolet mask blank system comprising: an ultra-low expansion substrate including surface imperfections; a planarization layer on the ultra-low expansion substrate for encapsulating the surface imperfections; a multi-layer stack over the planarization layer; and a bi-layer absorber over the multi-layer stack, the bi-layer absorber including a primary absorber layer and a secondary absorber layer deposited to a combined thickness of 30 nm and providing a reflectivity of less than 1.9%. an ultra-low expansion substrate including surface imperfections; a planarization layer on the ultra-low expansion substrate for encapsulating the surface imperfections; a multi-layer stack over the planarization layer; and a bi-layer absorber over the multi-layer stack, the bi-layer absorber including a primary absorber layer and a secondary absorber layer deposited to a combined thickness of 30 nm and providing a reflectivity of less than 1.9%.
An object avoidance system for an automated aerial vehicle, the object avoidance system comprising: an object detection element configured to be coupled to the automated aerial vehicle and configured to detect a presence of an object within a defined distance of the automated aerial vehicle; an avoidance determining element configured to be coupled to the automated aerial vehicle and configured to determine an avoidance maneuver, wherein the avoidance maneuver is determined based at least in part on an object vector (912, 914) representative of a distance and a direction of the object, and a defensive direction that is different than the direction of the object vector, wherein an avoidance vector is representative of the avoidance maneuver and a magnitude of the avoidance vector is greater than a magnitude of a velocity of the object with respect to the automated aerial vehicle; and a navigation component for automatically performing the avoidance maneuver. an object detection element configured to be coupled to the automated aerial vehicle and configured to detect a presence of an object within a defined distance of the automated aerial vehicle; an avoidance determining element configured to be coupled to the automated aerial vehicle and configured to determine an avoidance maneuver, wherein the avoidance maneuver is determined based at least in part on an object vector (912, 914) representative of a distance and a direction of the object, and a defensive direction that is different than the direction of the object vector, wherein an avoidance vector is representative of the avoidance maneuver and a magnitude of the avoidance vector is greater than a magnitude of a velocity of the object with respect to the automated aerial vehicle; and a navigation component for automatically performing the avoidance maneuver.
A mobile telephone housing, comprising a polyamide composition comprising, 20 to 70 weight percent of at least one polyamide component comprising, (a) 60 to 100 weight percent of at least one aliphatic polyamide wherein the aliphatic polyamide is one or more selected from the group consisting of polyamide 10,10; polyamide 10,12; polyamide 10,13; polyamide 10,14; polyamide 12,10; polyamide 12,12; polyamide 12,13; polyamide 12,14; polyamide 6,13, polyamide 6,14; polyamide 6,15; polyamide 6,16, polyamide 6,36; polyamide 9,10; polyamide 9,12; polyamide 9,13; polyamide 9,14; polyamide 9,15; polyamide 9,16; polyamide 9,36; copolymers of two more thereof; and blends thereof; and (b) 0 to 40 weight percent of at least one semiaromatic polyamide comprising about 60 to 100 of repeat units derived from one or more aromatic dicarboxylic acids; and 30 to 65 weight percent of one or more reinforcing agents; and 0 to 20 weight percent of one or more impact modifiers; wherein the weight percentages of (a) and (b) are based on the total weight of (a) + (b) and the weight percentages of,, and are based on the total weight of + +, and the composition has a tensile modulus greater than or equal to about 12 GPa, as measured by ISO 527-1/2 and a moisture absorption of less than or equal to about 0.4 weight percent, as measured by ISO 62. 20 to 70 weight percent of at least one polyamide component comprising, (a) 60 to 100 weight percent of at least one aliphatic polyamide wherein the aliphatic polyamide is one or more selected from the group consisting of polyamide 10,10; polyamide 10,12; polyamide 10,13; polyamide 10,14; polyamide 12,10; polyamide 12,12; polyamide 12,13; polyamide 12,14; polyamide 6,13, polyamide 6,14; polyamide 6,15; polyamide 6,16, polyamide 6,36; polyamide 9,10; polyamide 9,12; polyamide 9,13; polyamide 9,14; polyamide 9,15; polyamide 9,16; polyamide 9,36; copolymers of two more thereof; and blends thereof; and (b) 0 to 40 weight percent of at least one semiaromatic polyamide comprising about 60 to 100 of repeat units derived from one or more aromatic dicarboxylic acids; and (a) 60 to 100 weight percent of at least one aliphatic polyamide wherein the aliphatic polyamide is one or more selected from the group consisting of polyamide 10,10; polyamide 10,12; polyamide 10,13; polyamide 10,14; polyamide 12,10; polyamide 12,12; polyamide 12,13; polyamide 12,14; polyamide 6,13, polyamide 6,14; polyamide 6,15; polyamide 6,16, polyamide 6,36; polyamide 9,10; polyamide 9,12; polyamide 9,13; polyamide 9,14; polyamide 9,15; polyamide 9,16; polyamide 9,36; copolymers of two more thereof; and blends thereof; and (b) 0 to 40 weight percent of at least one semiaromatic polyamide comprising about 60 to 100 of repeat units derived from one or more aromatic dicarboxylic acids; and 30 to 65 weight percent of one or more reinforcing agents; and 0 to 20 weight percent of one or more impact modifiers;
Open roof construction for a vehicle, comprising a roof opening in a stationary roof part, a movable panel for opening and closing said roof opening and two panel operating assemblies positioned at two opposite longitudinal sides of the roof opening and each comprising a panel guide and a panel moving mechanism at a certain longitudinal position, wherein as seen in the longitudinal direction of the vehicle, the panel operating assemblies each have a varying width in the transverse direction of the vehicle, wherein the panel moving mechanism is not present at least at the part of a panel operating assembly with the smallest width, characterized by a movable blind for cooperation with the roof opening and two blind guides positioned at two opposite longitudinal sides of the roof opening, wherein each blind guide at least partly follows the contour provided by the varying width of a corresponding one of the panel operating assemblies.
Method for generating a medical data set, which is an image data set, of a moving part of the human or animal body, undergoing a cyclical movement such as cardiac movement, comprising the following steps: a) receiving a raw data signal acquired by a magnetic resonance receiver coil arrangement, characterised by the following steps: b) separating a magnetic resonance signal and a movement signal from the raw data signal, wherein the movement signal is derived from and/or describes the mechanical activity of the moving body part within a movement cycle, wherein the movement signal is the cardiac component of a Pilot Tone signal, c) automatically assigning at least two physiological phases (40, 42, 46, 48) of the moving body part to the movement signal, wherein the automatic assignment does not introduce a delay between the movement signal and the magnetic resonance signal, d) automatic determination and/or setting of time points (160, 170, 180) used for triggering an acquisition of the magnetic resonance signal and/or for data post-processing of the magnetic resonance signal, wherein the time points are extracted from the movement signal. a) receiving a raw data signal acquired by a magnetic resonance receiver coil arrangement, b) separating a magnetic resonance signal and a movement signal from the raw data signal, wherein the movement signal is derived from and/or describes the mechanical activity of the moving body part within a movement cycle, wherein the movement signal is the cardiac component of a Pilot Tone signal, c) automatically assigning at least two physiological phases (40, 42, 46, 48) of the moving body part to the movement signal, wherein the automatic assignment does not introduce a delay between the movement signal and the magnetic resonance signal, d) automatic determination and/or setting of time points (160, 170, 180) used for triggering an acquisition of the magnetic resonance signal and/or for data post-processing of the magnetic resonance signal, wherein the time points are extracted from the movement signal.
A strapping head for a strapping machine, comprising a containment frame suitable to house at least a strap launch/rewind path defined by a launch/tensioning assembly comprising a plurality of driving wheels (10, 11, 12, 13, 14, 15) of said strap, a welding assembly and a gripping and cutting device comprising locking grippers, a moving abutment plate and a cutter, said driving wheels of the launch/tensioning assembly being brought into rotation by a first actuation motor (M 1), characterised in that all of said launch/tensioning assembly, welding assembly and gripping and cutting device have driving members driven into movement through a single linear cam apt to move alternately in the longitudinal direction through a second actuation motor (M 2) and having cam profiles both on an horizontal plane and on a vertical plane, and in that said linear cam is actuated by said second actuation motor (M 2) being connected in rotation with screwed spindle transmission means mutually cooperating with screw nut means integral with said linear cam.
Composite fibre, especially a conducting one, consisting of a thermoplastic polymeric matrix comprising a polyetherketoneketone (PEKK) in which multi-walled nanotubes are dispersed.