mhurhangee/ep-ind-claims huggingface dataset:
A flexible portable apparatus comprising: a folding portion configured to bend at one end of a body of a flexible portable terminal in a direction to a front surface or a rear surface of the flexible portable terminal; and a flexible display unit configured to be mounted on the body of the flexible portable terminal, and to bend in the front surface or the rear surface of the flexible portable terminal according to a bending direction of the folding portion, characterized in that the portable apparatus further comprises at least one sliding portion configured to enable one end of the flexible display unit to slide according to a difference of a compression or tension caused by a difference of an elongation between the folding portion and the flexible display unit when the folding portion is bent, the at least one sliding portion being disposed at an upper portion or a lower portion of the body of the flexible portable terminal, and the at least one sliding portion comprising: a slider (170; 172); a slot (120; 122) configured to define a sliding range of the slider, and is formed by etching a part of the surface of the body of the flexible portable terminal; and guide portions (131, 132; 141, 142) configured to guide a sliding of the slider at both ends of the slot; and wherein the flexible display unit is configured to be adhered to surface of the slider. a folding portion configured to bend at one end of a body of a flexible portable terminal in a direction to a front surface or a rear surface of the flexible portable terminal; and a flexible display unit configured to be mounted on the body of the flexible portable terminal, and to bend in the front surface or the rear surface of the flexible portable terminal according to a bending direction of the folding portion, characterized in that the portable apparatus further comprises at least one sliding portion configured to enable one end of the flexible display unit to slide according to a difference of a compression or tension caused by a difference of an elongation between the folding portion and the flexible display unit when the folding portion is bent, the at least one sliding portion being disposed at an upper portion or a lower portion of the body of the flexible portable terminal, and the at least one sliding portion comprising: a slider (170; 172); a slot (120; 122) configured to define a sliding range of the slider, and is formed by etching a part of the surface of the body of the flexible portable terminal; and guide portions (131, 132; 141, 142) configured to guide a sliding of the slider at both ends of the slot; and wherein the flexible display unit is configured to be adhered to surface of the slider. a slider (170; 172); a slot (120; 122) configured to define a sliding range of the slider, and is formed by etching a part of the surface of the body of the flexible portable terminal; and guide portions (131, 132; 141, 142) configured to guide a sliding of the slider at both ends of the slot; and wherein the flexible display unit is configured to be adhered to surface of the slider.
A diguanylate cyclase having an amino acid sequence selected from the group consisting of: the amino acid sequence shown under SEQ ID NO:6, an amino acid sequence having identity of 90% or higher with the amino acid sequence shown under SEQ ID NO:6, having 54th residue glycine in the amino acid sequence shown under SEQ ID NO:6 conserved, and with the lack of amino acid sequence KXXD in the i-site, and an amino acid sequence coded by the base sequence of a nucleic acid that hybridizes, under stringent conditions, with a nucleic acid having a base sequence complementary to a base sequence coding for the amino acid sequence shown under SEQ ID NO:6, having 54th residue glycine in the amino acid sequence shown under SEQ ID NO:6 conserved, and with the lack of amino acid sequence KXXD in the i-site_wherein stringent conditions are washing at 50 °C in a solution including 0.015M sodium chloride/0.0015M sodium citrate/0.1% sodium dodecyl sulfate. the amino acid sequence shown under SEQ ID NO:6, an amino acid sequence having identity of 90% or higher with the amino acid sequence shown under SEQ ID NO:6, having 54th residue glycine in the amino acid sequence shown under SEQ ID NO:6 conserved, and with the lack of amino acid sequence KXXD in the i-site, and an amino acid sequence coded by the base sequence of a nucleic acid that hybridizes, under stringent conditions, with a nucleic acid having a base sequence complementary to a base sequence coding for the amino acid sequence shown under SEQ ID NO:6, having 54th residue glycine in the amino acid sequence shown under SEQ ID NO:6 conserved, and with the lack of amino acid sequence KXXD in the i-site_wherein stringent conditions are washing at 50 °C in a solution including 0.015M sodium chloride/0.0015M sodium citrate/0.1% sodium dodecyl sulfate.
A circuit for providing a drive voltage to an ultracapacitor, the circuit comprising: a power source configured to provide a source voltage; an ultracapacitor that comprises a first electrode, a second electrode, a separator positioned between the first electrode and the second electrode, a nonaqueous electrolyte that is in ionic contact with the first electrode and the second electrode, and a housing within which the first electrode, the second electrode, the separator, and the electrolyte are retained; a temperature sensing device; a power converter configured to receive the source voltage and to supply a drive voltage to the ultracapacitor; and one or more control circuits configured to receive one or more signals indicative of a temperature associated with the ultracapacitor from the temperature sensing device and to control operation of the power converter based at least in part on the one or more signals indicative of the temperature associated with the ultracapacitor, characterized in that the one or more control circuits are configured to control operation of the power converter based at least in part on a derating curve associated with the ultracapacitor, the derating curve correlating temperature associated with the ultracapacitor to a drive voltage associated with the ultracapacitor, preferably wherein the derating curve specifies a decrease in drive voltage when the temperature associated with the ultracapacitor increases. a power source configured to provide a source voltage; an ultracapacitor that comprises a first electrode, a second electrode, a separator positioned between the first electrode and the second electrode, a nonaqueous electrolyte that is in ionic contact with the first electrode and the second electrode, and a housing within which the first electrode, the second electrode, the separator, and the electrolyte are retained; a temperature sensing device; a power converter configured to receive the source voltage and to supply a drive voltage to the ultracapacitor; and one or more control circuits configured to receive one or more signals indicative of a temperature associated with the ultracapacitor from the temperature sensing device and to control operation of the power converter based at least in part on the one or more signals indicative of the temperature associated with the ultracapacitor, characterized in that the one or more control circuits are configured to control operation of the power converter based at least in part on a derating curve associated with the ultracapacitor, the derating curve correlating temperature associated with the ultracapacitor to a drive voltage associated with the ultracapacitor, preferably wherein the derating curve specifies a decrease in drive voltage when the temperature associated with the ultracapacitor increases.
A vector for use in preventing or treating lymphedema, which is a mammalian expression vector into which a nucleic acid encoding an HGF has been inserted, wherein the vector comprises the nucleotide sequence of SEQ ID NO: 5.
Device for the cross-sectional shaping of a plurality of plastic strands guided in parallel next to one another via at least one rotatable shaping roller, in which the shaping roller is provided on its surface with a plurality of peripheral shaping depressions arranged in parallel, in which the cross section of the plastic strands can be shaped in accordance with the cross-sectional shape of the shaping depressions, the at least one shaping roller having rotary couplings on the front side for connection to supply and discharge lines for a liquid medium through the shaping roller, and the shaping roller being rotatably mounted on the front side in guide plates (10, 12) of a frame, wherein the at least one shaping roller is mounted in the guide plates (10, 12) by means of a quick-change device (24, 35), in which the rotary couplings are arranged on the front side so as to be central with respect to the quick-change devices (24, 35), and wherein the shaping roller can be removed from the frame after separation of the connections from the rotary couplings and removal of the quick-change devices (24, 35), characterized in that the quick-change device contains a hollow shaft receptacle which is guided through the guide plate and is intended for fixing an axial hollow shaft of the shaping roller, and comprises at least one pivot lever which releasably secures the hollow shaft receptacle to the guide plate, the hollow shaft resting, at the underside, on a support bar arranged on the guide plate, after the hollow shaft receptacle has been removed from the guide plate, before the shaping roller can be removed from the frame.
A fur processing apparatus, such as for processing mink fur, the apparatus comprising - a mandrel arranged for mounting of the fur with the fur side facing inwards, - a first scraper unit comprising at least one scraper roller with a plurality of scraper blades, the at least one scraper roller being arranged to rotate and for being pressed into contact with the fur on the mandrel while the at least one scraper roller rotates, and - a liquid spray unit arranged to spray a liquid onto the at least one scraper roller, such as water, so as to provide a liquid film on one or more of the plurality of scraper blades, characterised in a second scraper unit comprising a plurality of scraper rollers (S1_2, S2_2, S3_2), wherein the second scraper unit is arranged after the first scraper unit, seen in a direction of forward movement of the mandrel, and wherein a material dispenser is arranged between the first scraper unit and the second scraper unit, the material dispenser being arranged to apply an amount of particles, such as sawdust, to the fur. - a mandrel arranged for mounting of the fur with the fur side facing inwards, - a first scraper unit comprising at least one scraper roller with a plurality of scraper blades, the at least one scraper roller being arranged to rotate and for being pressed into contact with the fur on the mandrel while the at least one scraper roller rotates, and - a liquid spray unit arranged to spray a liquid onto the at least one scraper roller, such as water, so as to provide a liquid film on one or more of the plurality of scraper blades, characterised in a second scraper unit comprising a plurality of scraper rollers (S1_2, S2_2, S3_2), wherein the second scraper unit is arranged after the first scraper unit, seen in a direction of forward movement of the mandrel, and wherein a material dispenser is arranged between the first scraper unit and the second scraper unit, the material dispenser being arranged to apply an amount of particles, such as sawdust, to the fur.
A power management system for a noise reducing headset comprising: external receiving circuitry for receiving power from one of a plurality of external power sources; internal receiving circuitry for receiving power from an internal battery; electing circuitry for exclusively electing to receive electrical power from one of the circuitry for receiving power from the external power source or the internal battery; gain controlling circuitry, responsive to the electing circuitry for controlling a gain of active noise reduction circuitry; wherein the gain controlling circuitry causes the gain to be higher if the electing circuitry elects to receive power from the internal battery than if the electing circuitry elects to receive power from the external source. external receiving circuitry for receiving power from one of a plurality of external power sources; internal receiving circuitry for receiving power from an internal battery; electing circuitry for exclusively electing to receive electrical power from one of the circuitry for receiving power from the external power source or the internal battery; gain controlling circuitry, responsive to the electing circuitry for controlling a gain of active noise reduction circuitry; wherein the gain controlling circuitry causes the gain to be higher if the electing circuitry elects to receive power from the internal battery than if the electing circuitry elects to receive power from the external source.
A soy sauce containing ethyl lactate at a concentration of 20 ppm or more per 1 w/v% of total nitrogen concentration in the soy sauce and having a pH of less than 4.6.
Hydraulic braking circuit for a vehicle comprising: - a master cylinder - a hydraulic pump - means for injecting an additional volume characterized in that said means comprise a bladder comprising, at its periphery, a metallic braid, porous to air and retaining a membrane for injecting an additional volume of hydraulic liquid through suction by the hydraulic pump, this suction deforming a membrane of the bladder under a depression effect. - a master cylinder - a hydraulic pump - means for injecting an additional volume characterized in that said means comprise a bladder comprising, at its periphery, a metallic braid, porous to air and retaining a membrane for injecting an additional volume of hydraulic liquid through suction by the hydraulic pump, this suction deforming a membrane of the bladder under a depression effect.
An antibody binding to the second extracellular loop of human C5aR, wherein the variable region of the heavy chain of said antibody comprises a CDR1, a CDR2 and a CDR3 sequence, wherein said CDR sequences comprise the sequences SEQ ID NOs: 9, 10 and 11, respectively, and wherein the variable region of the light chain of said antibody comprises a CDR1, a CDR2 and a CDR3 sequence, wherein said CDR sequences comprise the sequences SEQ ID NOs: 13, 14 and 15, respectively, wherein the variable region of the heavy chain of said antibody comprises a sequence at least 90 % identical to SEQ ID NO: 12, and wherein the variable region of the light chain of said antibody comprises a sequence at least 90 % identical to SEQ ID NO: 16.
6-thio-2'-deoxyguanosine (6-thio-dG) for use in a method of treating a cancer, in a subject, said method comprising administering 6-thio-dG to said subject followed by treatment with an immune checkpoint inhibitor, wherein the cancer is selected from the group consisting of pancreatic, lung, stomach, liver, bladder, head & neck, oral, nasopharyngeal, colon, prostate, ovarian, cervical, testicular, lymphoma, leukemia, and skin, wherein the immune checkpoint inhibitor is atezolizumab.
A valve assembly (1, 101) for use in a wellbore of an oil, gas or water well, the valve assembly having a bore (1b, 101b) with an axis, the assembly having a valve seat (20, 120) adapted to seat a valve closure member (10, 110), the assembly comprising an outlet port (52, 152) and a control sleeve (60, 160) adapted to cycle the valve assembly between a first configuration and a second configuration of the valve assembly, wherein in the first configuration of the valve assembly, the control sleeve is configured to obturate the outlet port and to restrict fluid communication between the bore and the outlet port; and wherein in the second configuration the control sleeve is configured to allow at least partial fluid communication between the bore and the outlet port; and wherein the valve assembly is repeatedly cyclable between the first and second configurations of the valve assembly, while the valve closure member is seated on the valve seat, by changes in fluid pressure acting on the seated valve closure member, characterized in that the control sleeve (60, 160) is castellated (68, 168) at a downhole end of the control sleeve.
A closure apparatus, comprising: a sub body having an annular opening; a closure door carried by the sub body and movable thereto between an open position and a closed position; a plurality of arcuate segments arranged between the closure door and the sub body in the closed position wherein bracketless gaps are defined between adjacent arcuate segments; a drive hub rotatably mounted to the closure door for rotation about a drive axis; and a plurality of cross bars, each cross bar having a first end pivotably mounted to drive hub and a second end pivotably mounted to one of the arcuate segments. characterised in that it further comprises a plurality of retainers mounted to the closure door, each retainer acting upon one of the cross bars between the first and second ends allowing the cross bar to move radially and float axially relative to the drive axis; and in that the sub body includes a wedge shaped recess and in that each arcuate segment includes a wedge shaped projection engaging the wedge shaped recess in the closed position, wherein during movement from the open to the closed position, the wedge shaped projection of each arcuate segment self-adjusts and self-locates as it coacts with the wedge shaped recess due to the cross bar floating axially. a sub body having an annular opening; a closure door carried by the sub body and movable thereto between an open position and a closed position; a plurality of arcuate segments arranged between the closure door and the sub body in the closed position wherein bracketless gaps are defined between adjacent arcuate segments; a drive hub rotatably mounted to the closure door for rotation about a drive axis; and a plurality of cross bars, each cross bar having a first end pivotably mounted to drive hub and a second end pivotably mounted to one of the arcuate segments.
A multi-connected heat recovery air conditioning system comprising an indoor unit, an outdoor unit, and a hydraulic module, wherein the outdoor unit includes a compressor, an outdoor heat exchanger, a first four-way valve and a second four-way valve; the hydraulic module including a heat exchange water tank, ports d, e, c and s of the first four-way valve being connected to an output end of the compressor, one end of the indoor unit, port g of the second four-way valve, and a return end of the compressor, respectively, ports h, i, and f of the second four-way valve being connected to the outdoor heat exchanger, the return end of the compressor, and one end of a refrigerant flow path of the heat exchange water tank, respectively, the other end of the refrigerant flow path of the heat exchange water tank being connected in a bypass manner between a first solenoid valve and the outdoor heat exchanger via a first check valve, the other end of the outdoor unit being connected to the indoor unit; the outdoor heat exchanger comprising three heat exchange coils arranged in parallel in a wind direction of the wind blades thereof, wherein the three heat exchange coils are connected together at one end to connect to port h of the second four-way valve, and the other end of the three heat exchange coils are connected to preset first outdoor expansion valve, second outdoor expansion valve and third outdoor expansion valve, respectively, and then joint together to connect to the outdoor unit; it further comprises an indoor unit temperature unit arranged in the indoor unit for detecting and obtaining an outlet temperature value of the indoor unit, a water temperature unit arranged at the heat exchange water tank for detecting and obtaining water temperature, and a high-pressure sensor and a low-pressure sensor arranged respectively at the output end and the return end of the compressor.
A process for preparing tert-butyl(((3aR,4R,6aR)-5-fluoro-2,2-dimethyl-6-((trityloxy)methyl)-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)diphenylsilane comprising: hydrolyzing a boronic acid intermediate of tert-butyl(((3aR,4R,6aR)-5-iodo-2,2-dimethyl-6-((trityloxy)methyl)-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)diphenylsilane, and reacting the hydrolysate with 1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate) to obtain tert-butyl(((3aR,4R,6aR)-5-fluoro-2,2-dimethyl-6-((trityloxy)methyl)-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)diphenylsilane. hydrolyzing a boronic acid intermediate of tert-butyl(((3aR,4R,6aR)-5-iodo-2,2-dimethyl-6-((trityloxy)methyl)-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)diphenylsilane, and reacting the hydrolysate with 1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate) to obtain tert-butyl(((3aR,4R,6aR)-5-fluoro-2,2-dimethyl-6-((trityloxy)methyl)-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)diphenylsilane.
A method, implemented using a computer system that includes one or more processors and system memory, for screening a plurality of different enzyme variants for activity with a substrate, wherein the plurality of different enzyme variants comprises at least ten different variants, and the enzyme variants comprise active sites that differ from one another by at least one mutation in the amino acid sequence of the active site, the method comprising: (a) creating or receiving a structural model for each of the plurality of different enzyme variants, wherein each structural model contains a three dimensional computational representation of an active site of an enzyme variant; (b) for each enzyme variant, docking, by the computer system, a computational representation of the substrate to the three dimensional computational representation of the active site of the enzyme variant, wherein docking (i) generates a plurality of poses of the substrate in the active site, wherein a pose comprises a position or orientation of the substrate with respect to the active site of the enzyme variant, and (ii) identifies energetically favorable poses of the substrate in the active site, wherein an energetically favorable pose is a pose having an energy that is favorable for binding between the substrate and the enzyme variant; (c) for each energetically favorable pose, determining whether the pose is active, wherein an active pose meets one or more constraints for the substrate to undergo a catalytic reaction in the active site; and (d) selecting at least one of the enzyme variants having an active site in which the substrate has one or more active poses as determined in (c). (a) creating or receiving a structural model for each of the plurality of different enzyme variants, wherein each structural model contains a three dimensional computational representation of an active site of an enzyme variant; (b) for each enzyme variant, docking, by the computer system, a computational representation of the substrate to the three dimensional computational representation of the active site of the enzyme variant, wherein docking (i) generates a plurality of poses of the substrate in the active site, wherein a pose comprises a position or orientation of the substrate with respect to the active site of the enzyme variant, and (ii) identifies energetically favorable poses of the substrate in the active site, wherein an energetically favorable pose is a pose having an energy that is favorable for binding between the substrate and the enzyme variant; (c) for each energetically favorable pose, determining whether the pose is active, wherein an active pose meets one or more constraints for the substrate to undergo a catalytic reaction in the active site; and (d) selecting at least one of the enzyme variants having an active site in which the substrate has one or more active poses as determined in (c).
Paint formulations comprising at least one pigment and/or filler, at least one binder and from 0.05 to 7% by weight of a polygalactomannan ether prepared from polygalactomannans obtained from Cassia obtusifolia (cassia gum).