mhurhangee/ep-ind-claims huggingface dataset:
A compound having the Formula II: or a pharmaceutically acceptable salt or hydrate, wherein: A is (CH 2) k Y'; k is 0, 1, or 2; Y' is OR 2 or NR 2 R 3; R 1 is selected from H, C 1-10 alkyl, C 6-20 aryl and C 7-20 aralkyl; B is NHC and Z is phenyl optionally substituted with 1-5 Q groups; E is selected from C OH and C NH 2; Q, at each occurrence, independently is selected from C- 1-10 alkyl, C 2-10 alkenyl, C 2-10 alkynyl, C 3-20 cycloalkyl, C 6-20 aryl, C 7-20 aralkyl, 3-20 membered cycloheteroalkyl, 5-20 membered heteroaryl, F, Cl Br, I, CN, CF 3, OCF 3, NO 2, OR 8, SR 8, S + R 8 2, S R 8, S 2 R 8, S 2 OH S 2 NR 8 R 9, NR 8 S 2 R 9, C R 8, C OR 8, C NR 8 R 9, OC R 8, NR 8 R 9, NR 8 C R 9, NR 8 C OR 9, NR 8 C NR 8 R 9, and N + R 8 3; R 2 and R 3 each independently is selected from H; C 1-10 alkyl, C 3-20 cycloalkyl, C 7-20 aralkyl, C 6-20 aryl, 3-20 membered cycloheteroalkyl, 5-20 membered heteroaryl, C R 6, C OR 6, C NR 6 R 7, S 2 R 6, and S 2 NR 6 R 7; alternatively, R 2 and R 3 together with the nitrogen atom to which they are bound form a 3-20 membered heterocycle optionally containing 1-4 ring heteroatoms independently selected from O, N or S and optionally substituted with 1-5 Q groups; R 6 and R 7 each independently is selected from H and C 1-10 alkyl; R 8 and R 9 each independently is selected from H and C 1-10 alkyl; provided that the compound is not 1-(2-aminopropanoyl)-4-benzamidopyrrolidine-2-carboxylic acid. A is (CH 2) k Y'; k is 0, 1, or 2; Y' is OR 2 or NR 2 R 3; R 1 is selected from H, C 1-10 alkyl, C 6-20 aryl and C 7-20 aralkyl; B is NHC and Z is phenyl optionally substituted with 1-5 Q groups; E is selected from C OH and C NH 2; Q, at each occurrence, independently is selected from C- 1-10 alkyl, C 2-10 alkenyl, C 2-10 alkynyl, C 3-20 cycloalkyl, C 6-20 aryl, C 7-20 aralkyl, 3-20 membered cycloheteroalkyl, 5-20 membered heteroaryl, F, Cl Br, I, CN, CF 3, OCF 3, NO 2, OR 8, SR 8, S + R 8 2, S R 8, S 2 R 8, S 2 OH S 2 NR 8 R 9, NR 8 S 2 R 9, C R 8, C OR 8, C NR 8 R 9, OC R 8, NR 8 R 9, NR 8 C R 9, NR 8 C OR 9, NR 8 C NR 8 R 9, and N + R 8 3; R 2 and R 3 each independently is selected from H; C 1-10 alkyl, C 3-20 cycloalkyl, C 7-20 aralkyl, C 6-20 aryl, 3-20 membered cycloheteroalkyl, 5-20 membered heteroaryl, C R 6, C OR 6, C NR 6 R 7, S 2 R 6, and S 2 NR 6 R 7; alternatively, R 2 and R 3 together with the nitrogen atom to which they are bound form a 3-20 membered heterocycle optionally containing 1-4 ring heteroatoms independently selected from O, N or S and optionally substituted with 1-5 Q groups; R 6 and R 7 each independently is selected from H and C 1-10 alkyl; R 8 and R 9 each independently is selected from H and C 1-10 alkyl; provided that the compound is not 1-(2-aminopropanoyl)-4-benzamidopyrrolidine-2-carboxylic acid.
Refrigeration and/or freezing device having at least one Biofresh compartment, at least one communication module and at least one hardware module, wherein the communication module is designed for connection of the hardware module to a server, which in particular is external, characterised in that the hardware module is a biochemical sensor, which is configured to measure an increased bacterial load and/or an increased CO 2 value inside the Biofresh compartment.
Backing pad (30; 50; 60) for a hand guided polishing or sanding tool, the backing pad (30; 50; 60) having an essentially plate-like form and a trapezoid cross-section with a top surface (30a; 50a; 60a), a bottom surface (30b; 50b; 60b) and a slanting circumferential surface (17; 37) resulting in the bottom surface (30b; 50b; 60b) being larger than the top surface (30a; 50a; 60a), the backing pad (30; 50; 60) being adapted to be fixedly connected to a moving mounting part of the tool at its top surface (30a; 50a; 60a) and to receive a polishing or sanding material on the bottom surface (30b; 50b; 60b), the backing pad (30; 50; 60) being provided with a plurality of channels (16; 36) each extending essentially radially and essentially parallel to the top and bottom surfaces (30a, 30b; 50a, 50b; 60a, 60b) through at least part of the backing pad (30; 50; 60), a central recess (15; 34) located in the bottom surface (30b; 50b; 60b) and a plurality of holes (13; 35) each having a longitudinal extension essentially perpendicular to the top and bottom surfaces (30a, 30b; 50a, 50b; 60a, 60b) through the backing pad (30; 50; 60) and connecting an opening (13b; 35b) in the bottom surface (30b; 50b; 60b) with an opening (13a; 35a) in the top surface (30a; 50a; 60a), characterized in that the backing pad (30; 50; 60) is provided with at least one additional hole each located such that it ends in an opening in an annular outer section of the bottom surface (30b; 50b; 60b), the annular outer section located opposite to the slanting circumferential surface (17; 37) of the backing pad (30; 50; 60), and that the at least one additional hole ending in the opening in the annular outer section of the bottom surface (30b; 50b; 60b) of the backing pad (30; 50; 60) is in connection with at least one opening located in the top surface (30a; 50a; 60a) of the backing pad (30; 50; 60).
A mounting system for supporting tooling comprising a base block having a first block surface and a second block surface, the first block surface being configured to support an associated object such as tooling or additional tooling blocks, the base block further including a plunger passage (40; 42) and a stud passage, the plunger passage extending into the base block from the second block surface and extending inwardly along a plunger passage axis (56; 58), the stud passage extending into the base block from the first block surface along a stud passage axis and the stud passage axis being generally transverse to the plunger passage axis and radially spaced from the plunger passage axis, the stud passage partially intersecting the plunger passage forming a locking region between the plunger passage axis and stud passage axis, the system further including a plunger extending along a plunger body axis between an inner plunger end and an outer plunger end, the plunger including an outer side surface between the inner and outer plunger ends that extends about the plunger body axis, the plunger passage being shaped to receive the plunger in a sliding relationship and allowing the plunger to slide axially in the plunger passage along the passage axis, the plunger being axially positionable in the passage between an unlocked position and a locked position that are axially spaced from one another along the passage axis, the stud passage being shaped to receive an associated stud, the associated stud extending between a stud inner end and a stud outer end along a stud body axis, the associated stud having a stud cam between the stud ends transverse to the study body axis, characterised by the plunger having a radial cam region in the plunger outer side surface between the plunger ends (74, 76) facing radially outwardly from the plunger body axis, the radial cam region including an axially extending locking plunger cam and a clearance path axially adjacent the plunger cam along the plunger body axis, the stud cam being shaped to engage the plunger cam, when the plunger is in the unlocked condition the clearance path of the cam region is aligned with the stud passage allowing the stud cam of the associated stud to enter the locking region of the base block, once the stud cam is positioned in the locking region axial movement of the plunger along the plunger axis toward the locked position urging the plunger cam into the associated stud cam and the plunger cam at least partially axially aligning the associated stud in the stud passage, the engagement force between the plunger and stud cams urging the associated stud into a locked condition thereby locking the associated stud relative to the base block and providing a hold-down force between the base block and the associated stud.
A limb positioning device comprising: a clamp attachable to a patient support; a first support member configured to connect to the clamp; a second support member slidingly coupled to the first support member; a limb holder polyaxially and detachably coupled to the second support member; and a support wing, characterised in that said support wing is attached to and extends from the limb holder, the support wing having attachment features for coupling a retractor to the support wing. a clamp attachable to a patient support; a first support member configured to connect to the clamp; a second support member slidingly coupled to the first support member; a limb holder polyaxially and detachably coupled to the second support member; and a support wing, characterised in that said support wing is attached to and extends from the limb holder, the support wing having attachment features for coupling a retractor to the support wing.
A nonvolatile memory device comprising: a memory cell array including a meta data region storing chip-level information; control logic configured to identify a target cell in response to a received command; machine learning, ML, logic configured to infer an optimum parameter based on the chip-level information and physical information associated with the target cell applied as inputs to an artificial neural network model; and a buffer memory configured to store weight parameters of the artificial neural network model, wherein the memory cell array is implemented in a first chip manufactured on a first wafer, the ML logic and the buffer memory are implemented on a second chip manufactured on a second wafer different from the first wafer, and the first chip and the second chip are bonded using a chip-to-chip, C2C, bonding method, wherein the chip-level information includes wafer location information, wafer reliability information, and program/erase, P/E, cycle information, and wherein the physical information is associated with programming, reading and/or erasing the target cell and includes block information, word line information, and string selection information of the target cell. a memory cell array including a meta data region storing chip-level information; control logic configured to identify a target cell in response to a received command; machine learning, ML, logic configured to infer an optimum parameter based on the chip-level information and physical information associated with the target cell applied as inputs to an artificial neural network model; and a buffer memory configured to store weight parameters of the artificial neural network model, wherein the memory cell array is implemented in a first chip manufactured on a first wafer, the ML logic and the buffer memory are implemented on a second chip manufactured on a second wafer different from the first wafer, and the first chip and the second chip are bonded using a chip-to-chip, C2C, bonding method, wherein the chip-level information includes wafer location information, wafer reliability information, and program/erase, P/E, cycle information, and wherein the physical information is associated with programming, reading and/or erasing the target cell and includes block information, word line information, and string selection information of the target cell. wherein the chip-level information includes wafer location information, wafer reliability information, and program/erase, P/E, cycle information, and wherein the physical information is associated with programming, reading and/or erasing the target cell and includes block information, word line information, and string selection information of the target cell.
A supporting fixture for assembling/disassembling the gearbox of vehicles with increased operating flexibility, which comprises a load-bearing element which extends along a longitudinal axis and a pair of crossmembers (3, 4) which are associated with said supporting element, each one of which is associated with respective supporting means (5, 6) for supporting the gearbox of a vehicle undergoing maintenance from below, said supporting means of at least one of said crossmembers comprising at least one tilting support which is associated with said crossmember so that it can rotate about a respective angular position adjustment axis thereby to be adapted to assume different angular positions around the corresponding adjustment axis as a function of the type of gearbox to be supported, characterized in that said at least one crossmember is associated with said load-bearing element so that it can oscillate about said longitudinal axis.
A control system for a tractor fitted with two or more axles (21, 22) which carry wheels (13, 14) having pneumatic tyres and which is set up to pull an implement or trailer, the system having a display means for displaying to a tractor operator tractor performance parameters and having sensors to determine the current pull force applied to the implement or trailer and the current tractor ground speed, the system also having a processing unit which determines and advises the tractor operator via the display means; characterised in that the system includes a sensor that determines the current wheel load, and in that the processing unit determines and advises to the tractor operator via the display means as to an optimum weight of the tractor using a predetermined ratio of pull force /tractor weight and also the required load on each axle to achieve a predetermined optimum ratio between axle loads.
An indicia reading system, comprising: a mobile device comprising a camera, an illuminator, and a processor configured for running applications; a case for holding the mobile device, the case comprising a mirror movable between two configurations, the mirror to redirect an imaging direction of the camera when the mirror is moved into a field-of-view of the camera; characterized in that the mirror comprises visible markings that appear in images of the field-of-view reflected from the mirror; and the indicia reading system further comprises an indicia reading application running on the mobile device, the indicia reading application configuring the mobile device to (i) acquire images, (ii) analyze the acquired images for the visible markings, and (iii) adjust the mobile device for changing at least one settings based on detection of the visible markings. a mobile device comprising a camera, an illuminator, and a processor configured for running applications; a case for holding the mobile device, the case comprising a mirror movable between two configurations, the mirror to redirect an imaging direction of the camera when the mirror is moved into a field-of-view of the camera; characterized in that the mirror comprises visible markings that appear in images of the field-of-view reflected from the mirror; and the indicia reading system further comprises an indicia reading application running on the mobile device, the indicia reading application configuring the mobile device to (i) acquire images, (ii) analyze the acquired images for the visible markings, and (iii) adjust the mobile device for changing at least one settings based on detection of the visible markings.
A tubular sleeve comprising: a distal end opposite a proximal end; a cutout formed through the tubular sleeve proximate the distal end, the cutout defined in part by a first cutout edge and a second cutout edge, wherein the first cutout edge is positioned across the cutout from the second cutout edge; a first panel having at least a first side edge, a second side edge, and a trailing edge, the first panel affixed to the tubular sleeve to span a first portion of the cutout; a second panel having at least a first side edge, a second side edge, a leading edge and a trailing edge, the second panel affixed to the tubular sleeve to span a second portion of the cutout, the second-panel leading edge overlapping the first-panel trailing edge to define at least a portion of a first aperture, the first aperture being in communication with an interior volume of the tubular sleeve; and a third panel having at least a first side edge, a second side edge, and a leading edge, the third panel affixed to the tubular sleeve to span a third portion of the cutout, the third-panel leading edge overlapping the second-panel trailing edge to define at least a portion of a second aperture, the second aperture being in communication with the interior volume of the tubular sleeve, wherein the first side edges (1018, 1028, 1038) and the second side edges (1020, 1030, 1040) are affixed to an outer surface of the tubular sleeve along the first cutout edge and the second cutout edge, respectively, wherein the first side edge of the first panel extends around the tubular sleeve past the first cutout edge. a distal end opposite a proximal end; a cutout formed through the tubular sleeve proximate the distal end, the cutout defined in part by a first cutout edge and a second cutout edge, wherein the first cutout edge is positioned across the cutout from the second cutout edge; a first panel having at least a first side edge, a second side edge, and a trailing edge, the first panel affixed to the tubular sleeve to span a first portion of the cutout; a second panel having at least a first side edge, a second side edge, a leading edge and a trailing edge, the second panel affixed to the tubular sleeve to span a second portion of the cutout, the second-panel leading edge overlapping the first-panel trailing edge to define at least a portion of a first aperture, the first aperture being in communication with an interior volume of the tubular sleeve; and a third panel having at least a first side edge, a second side edge, and a leading edge, the third panel affixed to the tubular sleeve to span a third portion of the cutout, the third-panel leading edge overlapping the second-panel trailing edge to define at least a portion of a second aperture, the second aperture being in communication with the interior volume of the tubular sleeve, wherein the first side edges (1018, 1028, 1038) and the second side edges (1020, 1030, 1040) are affixed to an outer surface of the tubular sleeve along the first cutout edge and the second cutout edge, respectively, wherein the first side edge of the first panel extends around the tubular sleeve past the first cutout edge.
Electro-optical modulator device, comprising - at least one electro-optical modulator having a first and a second optical waveguide (112, 122) and an electrode arrangement for applying a voltage across the optical waveguide (112, 122), - wherein the electrode arrangement comprises a plurality of first waveguide electrodes 113) and a plurality of second waveguide electrodes arranged on top of the first and the second optical waveguide (112, 122), respectively, - wherein the first and second waveguide electrodes (113, 123) are capacitively coupled to one another; and - at least one driver unit for supplying a voltage to the electrode arrangement; and - an electrical connection between the driver unit (30, 30a-d) and the electrode arrangement; characterized in that the electrical connection between the driver unit (30, 30a-d) and the electrode arrangement comprises a flexible coplanar strip line (50, 50a-d), wherein the flexible coplanar strip line (50, 50a-d) comprises at least two electrical lines (51, 52), and wherein the flexible coplanar strip line (50, 50a-d) is a part of a flexible contact structure that in addition to the electrical lines (51, 52) of the flexible coplanar strip line (50, 50a-d) comprises a plurality of conducting lines connected to input contacts of an integrated circuit that forms the driver unit and configured for connecting external devices to the input contacts. - at least one electro-optical modulator having a first and a second optical waveguide (112, 122) and an electrode arrangement for applying a voltage across the optical waveguide (112, 122), - wherein the electrode arrangement comprises a plurality of first waveguide electrodes 113) and a plurality of second waveguide electrodes arranged on top of the first and the second optical waveguide (112, 122), respectively, - wherein the first and second waveguide electrodes (113, 123) are capacitively coupled to one another; and - at least one driver unit for supplying a voltage to the electrode arrangement; and - an electrical connection between the driver unit (30, 30a-d) and the electrode arrangement;
A method of navigating a self-propelled robotic tool, the method comprising transmitting a wireless signal along a first signal path between the robotic tool and a first wireless interface of a base station remote from the robotic tool; transmitting a wireless signal along a second signal path between the robotic tool and a second wireless interface of the base station, said second wireless interface being spatially separated from the first wireless interface by a separation distance; characterised in that upon receipt, comparing the signal transmitted along the first signa path with the signal transmitted along the second signal path to obtain a propagation time difference between the signal transmitted along the first signal path and the signal transmitted along the second signal path, said propagation time difference defining a path length difference (δ) between said first and second signal paths (66a, 66b); and calculating, based on the separation distance and the path length difference (δ), a value representative of a bearing (φ) from the base station to the robotic tool, wherein the signal transmitted along the first signal path is the same as the signal transmitted along the second signal path. transmitting a wireless signal along a first signal path between the robotic tool and a first wireless interface of a base station remote from the robotic tool; transmitting a wireless signal along a second signal path between the robotic tool and a second wireless interface of the base station, said second wireless interface being spatially separated from the first wireless interface by a separation distance; characterised in that upon receipt, comparing the signal transmitted along the first signa path with the signal transmitted along the second signal path to obtain a propagation time difference between the signal transmitted along the first signal path and the signal transmitted along the second signal path, said propagation time difference defining a path length difference (δ) between said first and second signal paths (66a, 66b); and calculating, based on the separation distance and the path length difference (δ), a value representative of a bearing (φ) from the base station to the robotic tool, wherein the signal transmitted along the first signal path is the same as the signal transmitted along the second signal path.
Coated silver nanoparticles having a mean particle diameter of 30 nm or less and coated with protective molecules, characterized in that the protective molecules contain as main components thereof a medium- to short- chain alkylamine having a boiling point within the range of 100°C to 250°C and a medium-to short- chain alkyldiamine having a boiling point within the range of 100°C to 250°C, wherein one of the amino groups possessed by the alkyldiamine is a tertiary amine.