A system for quantification of uncertainty of contours, said system comprising: at least one processor programmed to: receive an image including an object of interest, OOI; receive a band of uncertainty delineating a region in the received image, the region including the boundary of the OOI; delineate the boundary in the region; and, determine at least one metric of uncertainty of the delineation for the region, wherein the processor is further programmed to: for each of at least one of a plurality of sub-regions, into which the region is divided: determine whether to filter the sub-region, the determination including at least one of: determining whether the boundary of the OOI can be delineated in the sub-region with a confidence level exceeding a first predetermined level; and, determining whether a stopping condition is met, the stopping condition indicating the confidence level is less than a second predetermined level; in response to determining the boundary of the OOI can be delineated in the sub-region with the confidence level exceeding the first predetermined level or the stopping condition being met, delineate the boundary of the OOI in the sub-region; and, in response to determining the boundary of the OOI cannot be delineated in the sub-region with the confidence level exceeding the first predetermined level and the stopping condition not being met, iteratively filter the sub-region a predetermined number of times with a filtering algorithm for enhancing edges and repeat the determination as to whether to filter the sub-region. at least one processor programmed to: receive an image including an object of interest, OOI; receive a band of uncertainty delineating a region in the received image, the region including the boundary of the OOI; delineate the boundary in the region; and, determine at least one metric of uncertainty of the delineation for the region, receive an image including an object of interest, OOI; receive a band of uncertainty delineating a region in the received image, the region including the boundary of the OOI; delineate the boundary in the region; and, determine at least one metric of uncertainty of the delineation for the region, wherein the processor is further programmed to: for each of at least one of a plurality of sub-regions, into which the region is divided: determine whether to filter the sub-region, the determination including at least one of: determining whether the boundary of the OOI can be delineated in the sub-region with a confidence level exceeding a first predetermined level; and, determining whether a stopping condition is met, the stopping condition indicating the confidence level is less than a second predetermined level; in response to determining the boundary of the OOI can be delineated in the sub-region with the confidence level exceeding the first predetermined level or the stopping condition being met, delineate the boundary of the OOI in the sub-region; and, in response to determining the boundary of the OOI cannot be delineated in the sub-region with the confidence level exceeding the first predetermined level and the stopping condition not being met, iteratively filter the sub-region a predetermined number of times with a filtering algorithm for enhancing edges and repeat the determination as to whether to filter the sub-region. determine whether to filter the sub-region, the determination including at least one of: determining whether the boundary of the OOI can be delineated in the sub-region with a confidence level exceeding a first predetermined level; and, determining whether a stopping condition is met, the stopping condition indicating the confidence level is less than a second predetermined level; determining whether the boundary of the OOI can be delineated in the sub-region with a confidence level exceeding a first predetermined level; and, determining whether a stopping condition is met, the stopping condition indicating the confidence level is less than a second predetermined level; in response to determining the boundary of the OOI can be delineated in the sub-region with the confidence level exceeding the first predetermined level or the stopping condition being met, delineate the boundary of the OOI in the sub-region; and, in response to determining the boundary of the OOI cannot be delineated in the sub-region with the confidence level exceeding the first predetermined level and the stopping condition not being met, iteratively filter the sub-region a predetermined number of times with a filtering algorithm for enhancing edges and repeat the determination as to whether to filter the sub-region.