Reagent vessel insert with: an insert housing, which is formed such that the reagent vessel insert can be inserted in a reagent vessel for a centrifuge and/or for a pressure varying device; at least one magnet (12, 12a, 12b), which is arranged non-adjustably with respect to the insert housing; at least one adjusting element (16, 16a, 16b), which is arranged in an interior volume of the reagent vessel insert; a cutting edge, a point and/or a spike; and a layer that can be penetrated, the at least one adjusting element (16, 16a, 16b) being at least partially formed from a magnetically attractable material, the at least one magnet (12, 12a, 12b) being formed in such a way that a magnetic force of attraction exerted on the at least one adjusting element (16, 16a, 16b) is at least greater than a force of the weight of the at least one adjusting element (16, 16a, 16b), the at least one adjusting element (16, 16a, 16b) being adjustable with respect to the at least one magnet (12, 12a, 12b) by means of a centrifugal force that can be brought about when operating the centrifuge in the rotor device of which the reagent vessel with the reagent vessel insert inserted therein is arranged and is greater than the magnetic force of attraction and/or by means of a compressive force that can be brought about when operating the pressure varying device in which the reagent vessel with the reagent vessel insert inserted therein is arranged and is greater than the magnetic force of attraction, characterized in that it is possible by means of the at least one adjusting element (16, 16a, 16b) that is adjustable with respect to the at least one magnet (12, 12a, 12b) for the cutting edge, the point and/or the spike to be brought into contact with the layer that can be penetrated by means of the cutting edge, the point and/or the spike. an insert housing, which is formed such that the reagent vessel insert can be inserted in a reagent vessel for a centrifuge and/or for a pressure varying device; at least one magnet (12, 12a, 12b), which is arranged non-adjustably with respect to the insert housing; at least one adjusting element (16, 16a, 16b), which is arranged in an interior volume of the reagent vessel insert; a cutting edge, a point and/or a spike; and a layer that can be penetrated, the at least one adjusting element (16, 16a, 16b) being at least partially formed from a magnetically attractable material, the at least one magnet (12, 12a, 12b) being formed in such a way that a magnetic force of attraction exerted on the at least one adjusting element (16, 16a, 16b) is at least greater than a force of the weight of the at least one adjusting element (16, 16a, 16b), the at least one adjusting element (16, 16a, 16b) being adjustable with respect to the at least one magnet (12, 12a, 12b) by means of a centrifugal force that can be brought about when operating the centrifuge in the rotor device of which the reagent vessel with the reagent vessel insert inserted therein is arranged and is greater than the magnetic force of attraction and/or by means of a compressive force that can be brought about when operating the pressure varying device in which the reagent vessel with the reagent vessel insert inserted therein is arranged and is greater than the magnetic force of attraction, characterized in that it is possible by means of the at least one adjusting element (16, 16a, 16b) that is adjustable with respect to the at least one magnet (12, 12a, 12b) for the cutting edge, the point and/or the spike to be brought into contact with the layer that can be penetrated by means of the cutting edge, the point and/or the spike.