mhurhangee/ep-ind-claims huggingface dataset:
A turning and face grooving tool body having a pocket and a pin, the pin having a unitary one-piece construction and an elongated shape defining a longitudinal direction along a pin axis P; the pin comprising: pin top and bottom ends (50, 52); a pin peripheral surface extending therebetween; and a pivot protrusion extending outwardly in a first direction from the pin peripheral surface; the pocket comprising: a base surface and transverse support walls which converge in an inward direction of the pocket, parallel to the base surface; and a pin bore comprising a pin bore inner surface and opening out to the base surface; wherein the pin is located in the pin bore and the pin top end protrudes beyond the base surface; the pin is rotationally asymmetric about the longitudinal pin axis P; the pivot protrusion is spaced apart from the pin top and bottom ends (50, 52) and offset in the longitudinal direction from a pin midway-point located midway between the pin top and bottom ends (50, 52); and characterised in that the pin top end has a triangular cross section when viewed in the longitudinal direction. the pin comprising: pin top and bottom ends (50, 52); a pin peripheral surface extending therebetween; and a pivot protrusion extending outwardly in a first direction from the pin peripheral surface; pin top and bottom ends (50, 52); a pin peripheral surface extending therebetween; and a pivot protrusion extending outwardly in a first direction from the pin peripheral surface; the pocket comprising: a base surface and transverse support walls which converge in an inward direction of the pocket, parallel to the base surface; and a pin bore comprising a pin bore inner surface and opening out to the base surface; a base surface and transverse support walls which converge in an inward direction of the pocket, parallel to the base surface; and a pin bore comprising a pin bore inner surface and opening out to the base surface; wherein the pin is located in the pin bore and the pin top end protrudes beyond the base surface; the pin is rotationally asymmetric about the longitudinal pin axis P; the pivot protrusion is spaced apart from the pin top and bottom ends (50, 52) and offset in the longitudinal direction from a pin midway-point located midway between the pin top and bottom ends (50, 52); and characterised in that the pin top end has a triangular cross section when viewed in the longitudinal direction. the pin is located in the pin bore and the pin top end protrudes beyond the base surface; the pin is rotationally asymmetric about the longitudinal pin axis P; the pivot protrusion is spaced apart from the pin top and bottom ends (50, 52) and offset in the longitudinal direction from a pin midway-point located midway between the pin top and bottom ends (50, 52); and characterised in that the pin top end has a triangular cross section when viewed in the longitudinal direction.
A method of producing a modified chimeric antigen receptor T cell, the method comprising: providing a T cell and introducing a nucleic acid sequence encoding a chimeric antigen receptor and a nucleic acid encoding hTERT, a nucleic acid encoding SV40 large T antigen (SV40LT), or a combination thereof into the cell wherein the nucleic acid encoding hTERT, SV40LT, or a combination thereof is integrated by genomic integration of the nucleic acid sequence encoding hTERT, a nucleic acid encoding SV40LT, or a combination thereof and constitutive expression of hTERT, SV40LT, or a combination thereof; or the expression of hTERT, SV40LT, or a combination thereof is regulated by an inducible expression system; and culturing the cell in the presence of an agent that is recognized by the extracellular domain of the CAR, thereby producing a modified CAR T cell. providing a T cell and introducing a nucleic acid sequence encoding a chimeric antigen receptor and a nucleic acid encoding hTERT, a nucleic acid encoding SV40 large T antigen (SV40LT), or a combination thereof into the cell wherein the nucleic acid encoding hTERT, SV40LT, or a combination thereof is integrated by genomic integration of the nucleic acid sequence encoding hTERT, a nucleic acid encoding SV40LT, or a combination thereof and constitutive expression of hTERT, SV40LT, or a combination thereof; or the expression of hTERT, SV40LT, or a combination thereof is regulated by an inducible expression system; and culturing the cell in the presence of an agent that is recognized by the extracellular domain of the CAR, thereby producing a modified CAR T cell.
A generally planar, conformable evaporative structure comprising: an envelope comprising substantially impermeable, flexible material (8, 9) containing: a layer of flexible wick material disposed adjacent to a major face of said envelope, adapted to hold a working fluid in liquid phase for evaporation by heat conducted through said envelope; a layer of flexible, breathable fabric adjacent to said layer of wick material; and one or more flexible rib(s) within said layer of breathable fabric, adapted to maintain pathway(s) for the flow of working fluid in vapour phase towards a condensation zone; wherein the working fluid is water; characterised in that a heat sink means is integrated with the evaporative structure at the condensation zone for condensation of said working fluid within the evaporative structure, and a heat exchanger is arranged in communication with the heat sink means, the heat exchanger being arranged to release heat to the environment, and wherein the evaporative structure is maintained under vacuum.
Piece of jewellery made of a noble metal or gemstone material with a surface which can be seen into, wherein a plurality of first optical elements are provided at the surface for creating lighting effects, characterised in that the first optical elements in each case comprise an arrangement of reflection surfaces let into the surface of the noble metal or gemstone material, by means of which a retroreflection can be created, and, addition to the first retroreflective optical elements, second optical elements, with different optical effects are additionally let into the surface of the noble metal or gemstone material.
Antenna for an NFC device, the antenna comprising at least one wire loop of a wire, wherein each wire loop delimits a loop area such that an electric current and/or an electric voltage in the wire is coupled to a magnetic flux that penetrates the loop area, and wherein the respective loop area of the at least one wire loop is bent or folded around a volume, characterized in that the wire of the at least one wire loop is shaped as follows: starting from an electric contacting area of the wire loop where the wire may be electrically connected to a control circuit, the wire forms a first half circle in a first plane and is then oriented perpendicular to the first plane towards a second plane that is arranged parallel to the first plane and then forms a circle, apart from a gap, in the second plane and is then oriented back towards the first plane and then forms a second half circle in the first plane to finally reach the electric contacting area, wherein the first half circle and the second half circle form a full circle, apart from two gaps.
An inhalation stick for inhalation through the nose, having an elongate housing sleeve and a rodshaped storage means for storing at least one essential oil, wherein the housing sleeve comprises an inner compartment to accommodate the storage means, wherein at least one fixing projection which protrudes into the compartment in the radial direction is provided in the interior in the housing sleeve for friction-fitted fixing of the storage means in the housing sleeve, characterized in that in order to close the housing sleeve, a plug sleeve is provided which can be inserted into the rear sleeve region and in that fixing projections which are provided with terminal feed-in stops and are formed as ribs are provided in the plug sleeve for terminal fixing of the storage means.
LED lamp (1; 9; 13; 17; 21; 25; 36; 40) comprising - at least one support (29; 32; 34) fitted with at least one LED, - a lamp base, - at least one circuit component connected to the lamp base and the at least one LED for operating the at least one LED, - a lamp body (5; 10; 14; 18; 22; 26; 39; 41) of translucent material, - wherein the lamp body (5; 10; 14; 18; 22; 26; 39; 41) comprises a surface structuring (6, 7; 11, 12; 15, 16; 19, 20; 23; 24; 27; 38; 42) for cooling by way of heat convection and - the surface structuring comprises a plurality of protrusions (6; 11; 15; 19; 23; 27; 38; 42), - the lamp body (5; 10; 14; 18; 22; 26; 39; 41) comprises a recess for receiving at least the part of the support (29; 32; 34) that supports the at least one LED, - the protrusions (6; 11; 15) are respectively configured in the form of islands. - at least one support (29; 32; 34) fitted with at least one LED, - a lamp base, - at least one circuit component connected to the lamp base and the at least one LED for operating the at least one LED, - a lamp body (5; 10; 14; 18; 22; 26; 39; 41) of translucent material, - wherein the lamp body (5; 10; 14; 18; 22; 26; 39; 41) comprises a surface structuring (6, 7; 11, 12; 15, 16; 19, 20; 23; 24; 27; 38; 42) for cooling by way of heat convection and - the surface structuring comprises a plurality of protrusions (6; 11; 15; 19; 23; 27; 38; 42), - the lamp body (5; 10; 14; 18; 22; 26; 39; 41) comprises a recess for receiving at least the part of the support (29; 32; 34) that supports the at least one LED, - the protrusions (6; 11; 15) are respectively configured in the form of islands.
A vessel for hydrolyzing acetone cyanohydrin by sulfuric acid (H 2 SO 4) to produce an hydrolysis mixture comprising α-sulfatoisobutyramide (SIBAM), said vessel comprising an agitation system for homogenizing the mixture, said vessel comprising at least one cooling system on its internal annular periphery area and it is divided into at least three stages along its vertical wall, each stage (S1 to S3) comprising a ACH feeding inlet (201, 202, 203) distributed along the vertical wall of the vessel and characterized in that: - the cooling system comprises vertical tubes bundle that comprises between 10 and 50 000 tubes, set up in the peripheral internal annular area of the vessel, said tubes extending on the height of the vessel and being traversed by a cooling water stream, - the agitation system comprises a shaft equipped with two impellers (215, 216) per stage (S1 to S3) of the vessel and - -between each stage (S1 to S3) is a separation baffle (213, 230) comprising a free central area and holes in its peripheral annular area for insertion of tubes of first cooling system. - the cooling system comprises vertical tubes bundle that comprises between 10 and 50 000 tubes, set up in the peripheral internal annular area of the vessel, said tubes extending on the height of the vessel and being traversed by a cooling water stream, - the agitation system comprises a shaft equipped with two impellers (215, 216) per stage (S1 to S3) of the vessel and - -between each stage (S1 to S3) is a separation baffle (213, 230) comprising a free central area and holes in its peripheral annular area for insertion of tubes of first cooling system.
Arrangement of a telescopic shock absorber, in particular for the wheel suspensions of motor vehicles, on a functional component, wherein a damper pipe of the telescopic shock absorber is securely connected to the functional component at an end opposite a piston rod via a clamping connection, and wherein above a base section of the damper pipe a reinforcement piece, which comprises a bushing supported on the damper pipe inner wall, is inserted into the damper pipe, characterised in that in the area of the clamping connection a base section is formed directly on the damper pipe and the reinforcement piece is composed of the bushing supported on the damper pipe inner wall with a central support disc reinforcing the latter.
A management system comprising: a receiver (51, 509) configured to receive a pubrequest to request distribution of information including a specific topic name from a first communication terminal that is authenticated by a first client and whose access to a first service is authorized and to receive a subrequest to receive a message including the specific topic name from a second communication terminal that is authenticated by a second client and whose access to a second service is authorized; and a distribution controller comprising a pub acceptance unit and a sub acceptance unit configured to control distribution of information related to the specific topic name to the second communication terminal based on whether the first service that is used by the first client and the second service that is used by the second client are each associated with the specific topic name, characterized in that the pub acceptance unit is configured to: determine whether authority to publish is obtained for the first service on the specific topic name, when it is determined that authority to publish is not obtained, further obtain a service to be inherited, which is associated with the first service that the first client is authorized to use, and determine whether authority to publish is obtained for the service to be inherited on the specific topic name, and determine that the first communication terminal has the authority to publish, when it is determined that authority to publish is obtained either for the first service or the service to be inherited. a receiver (51, 509) configured to receive a pubrequest to request distribution of information including a specific topic name from a first communication terminal that is authenticated by a first client and whose access to a first service is authorized and to receive a subrequest to receive a message including the specific topic name from a second communication terminal that is authenticated by a second client and whose access to a second service is authorized; and a distribution controller comprising a pub acceptance unit and a sub acceptance unit configured to control distribution of information related to the specific topic name to the second communication terminal based on whether the first service that is used by the first client and the second service that is used by the second client are each associated with the specific topic name, characterized in that the pub acceptance unit is configured to: determine whether authority to publish is obtained for the first service on the specific topic name, when it is determined that authority to publish is not obtained, further obtain a service to be inherited, which is associated with the first service that the first client is authorized to use, and determine whether authority to publish is obtained for the service to be inherited on the specific topic name, and determine that the first communication terminal has the authority to publish, when it is determined that authority to publish is obtained either for the first service or the service to be inherited.
A turbine engine airfoil comprising an airfoil structure having a wall providing an interior cooling channel and an exterior airfoil surface, a cooling passage provided in the wall fluidly connecting the interior cooling channel to the exterior airfoil surface, the cooling passage including at least one inlet and multiple outlets respectively adjoining the interior cooling channel and the exterior airfoil surface, wherein the airfoil has multiple inlets that each include an entrance at the interior cooling channel, and the outlets each include an exit at the exterior airfoil surface, the entrances having a greater cross-sectional area than that of the exits, characterized in that a first outlet has a different cross-sectional area than a second outlet.
A multimodal chromatography medium with anion exchange and cation exchange chromatographic capacity, said medium comprising: a porous solid support having an exterior surface and interior walls defining interior pores extending to openings in said exterior surface; organic ligands covalently bound to said interior walls, said ligands comprising first ion-exchange groups having a first charge, positive or negative; and micro-particles comprising second ion-exchange groups having a second charge, wherein said second charge is opposite to said first charge, said micro-particles being bound, directly or indirectly, to said exterior surface of said support wherein said micro-particles have a first average diameter and said interior pores have a second average diameter, said first average diameter of said micro-particles being larger than said second average diameter of said interior pores, essentially preventing said micro-particles from penetrating into said interior pores, said medium having anion exchange, cation exchange and reverse phase chromatographic capacity wherein said ligands comprise an alkyl chain having at least 8 carbon atoms in sequence, such that said alkyl chain provides said medium with reverse phase chromatographic capacity, said interior pores having a volume average diameter of 60 to 5000 Angstroms. a porous solid support having an exterior surface and interior walls defining interior pores extending to openings in said exterior surface; organic ligands covalently bound to said interior walls, said ligands comprising first ion-exchange groups having a first charge, positive or negative; and micro-particles comprising second ion-exchange groups having a second charge, wherein said second charge is opposite to said first charge, said micro-particles being bound, directly or indirectly, to said exterior surface of said support wherein said micro-particles have a first average diameter and said interior pores have a second average diameter, said first average diameter of said micro-particles being larger than said second average diameter of said interior pores, essentially preventing said micro-particles from penetrating into said interior pores, said medium having anion exchange, cation exchange and reverse phase chromatographic capacity wherein said ligands comprise an alkyl chain having at least 8 carbon atoms in sequence, such that said alkyl chain provides said medium with reverse phase chromatographic capacity, said interior pores having a volume average diameter of 60 to 5000 Angstroms.
An image-capturing device comprising: an image-capturing unit that captures a subject to output the captured image; a detection unit that physically detects a shake angle (θ) when the image-capturing unit has shaken; and a correction processing unit that calculates a correction amount (Δx, Δy) based on an arrangement position of a pixel constituting the image outputted by the image-capturing unit and the shake angle (θ) detected by the detection unit, to correct the image according to the correction amount (Δx, Δy), wherein the correction processing unit performs calculation according to a geometric and optical calculation formula to calculate the correction amount (Δx, Δy) for each pixel, by using a pupil distance (d) as an optical distance from a pupil position of an optical system for forming the image of the subject on a sensor surface of the image-capturing unit to the sensor surface of the image-capturing unit, an arrangement position of a predetermined pixel of the image supplied from the image-capturing unit, an elevation angle (α) from the pupil position with respect to a point on the sensor surface corresponding to the arrangement position, and the shake angle (θ). an image-capturing unit that captures a subject to output the captured image; a detection unit that physically detects a shake angle (θ) when the image-capturing unit has shaken; and a correction processing unit that calculates a correction amount (Δx, Δy) based on an arrangement position of a pixel constituting the image outputted by the image-capturing unit and the shake angle (θ) detected by the detection unit, to correct the image according to the correction amount (Δx, Δy), wherein the correction processing unit performs calculation according to a geometric and optical calculation formula to calculate the correction amount (Δx, Δy) for each pixel, by using a pupil distance (d) as an optical distance from a pupil position of an optical system for forming the image of the subject on a sensor surface of the image-capturing unit to the sensor surface of the image-capturing unit, an arrangement position of a predetermined pixel of the image supplied from the image-capturing unit, an elevation angle (α) from the pupil position with respect to a point on the sensor surface corresponding to the arrangement position, and the shake angle (θ).
A stable formulation for intrathecal administration comprising an arylsulfatase A protein at a concentration of at least 5 mg/ml and a poloxamer at a concentration ranging from 0.05-0.5%, wherein said formulation has a pH of 6-6.5 and wherein less than 5% of the arylsulfatase A protein exists in aggregated form.
A method of determining the position of a rotor in a brushless DC motor comprising the steps of: applying a sequence of current pulses to the stator phases, such that each stator phase experiences an equal number of current pulses in a first direction and such that each stator phase experiences an equal number of current pulses in a second opposite direction; measuring for each pulse the rise time for the stator phase current to exceed a predetermined threshold level; calculating the difference between the sum of rise times for current pulses generating current flows in the first direction in the respective stator phase and the sum of rise times for current pulses generating current flows in the second direction in the respective stator phase to generate respective scalar parameters for each stator phase, the respective scalar parameters being indicative of the inductance of each stator phase; and thereby determining the orientation of the rotor by ranking the scalar parameters in size order and characterized in that the ratios of the median value scalar parameter are calculated to the smallest value and to the largest value of the scalar parameters to determine how close to or far from alignment the rotor orientation is with the axis of the stator phase between the largest and smallest scalar parameters.
The use, in the lubrication of a spark-ignited or compression-ignited internal combustion engine, of an oil-soluble or oil-dispersible polymeric friction modifier, as an additive in an effective minor amount of at least 0.1 mass % based on the total mass of the lubricating oil composition, in a lubricating oil composition comprising an oil of lubricating viscosity in a major amount, to reduce and/or inhibit corrosion of the copper and/or lead, or an alloy of such metals, containing engine components during operation of the engine compared with a comparable lubricant which includes glycerol monooleate friction modifier and an oil-soluble or oil-dispersible dihydrocarbyl dithiophosphate metal salt, wherein: the oil-soluble or oil-dispersible polymeric friction modifier is the reaction product of only: (i) one or more polyisobutylene succinic anhydrides (PIBSAs); and, (ii) one or more poly(C 2 to C 6 alkylene) glycol(s); and, (iii) one or more C 2 to C 20 aliphatic hydrocarbyl polyols; and, (iv) one or more unsaturated acyclic C 6 to C 30 hydrocarbyl monocarboxylic acids; and, wherein the lubricating oil composition includes an oil-soluble or oil-dispersible dihydrocarbyl dithiophosphate metal salt, as an additive in an effective minor amount.