mhurhangee/ep-ind-claims huggingface dataset:
A method for preparing hydrogenated bisphenol A, comprising: (a) heating a reactor in which bisphenol A, a solvent, and a ruthenium supported catalyst are added; (b) reacting while supplying hydrogen into the reactor; (c) reacting after blocking the supply of hydrogen; characterized in that the reaction temperature in each of steps (b) and (c) is 130 to 160°C, the reaction time in step (b) is 30 to 180 minutes, the reaction time in step (c) is 40 to 90 minutes, and the ratio of trans/trans isomer of hydrogenated bisphenol A in the product of step (c) is 45% or more. (a) heating a reactor in which bisphenol A, a solvent, and a ruthenium supported catalyst are added; (b) reacting while supplying hydrogen into the reactor; (c) reacting after blocking the supply of hydrogen; the reaction temperature in each of steps (b) and (c) is 130 to 160°C, the reaction time in step (b) is 30 to 180 minutes, the reaction time in step (c) is 40 to 90 minutes, and the ratio of trans/trans isomer of hydrogenated bisphenol A in the product of step (c) is 45% or more.
A compound for use as a medicament by inhibiting Stat3 in a cell, wherein the compound is selected from the group consisting of: 4-[({3-[(carboxymethyl)thio]-4-hydroxy-1-naphthyl}amino)sulfonyl] benzoic acid (Cpd 188) 4{5-[(3-ethyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-2-furyl}benzoic acid (Cpd 30) 4-chloro-3-{5-[(1,3-diethyl-4,6-dioxo-2-thioxotetrahydro-5 -pyrimidinylidene)methyl]-2-furyl}benzoic acid (Cpd 30-12) and a mixture thereof, wherein the cell is in vivo in a human, and wherein the human is known, suspected, or at risk for developing cancer, a hyperproliferative disease, pulmonary fibrosis, asthma, or inflammatory bowel disease. 4-[({3-[(carboxymethyl)thio]-4-hydroxy-1-naphthyl}amino)sulfonyl] benzoic acid (Cpd 188) 4{5-[(3-ethyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-2-furyl}benzoic acid (Cpd 30) 4-chloro-3-{5-[(1,3-diethyl-4,6-dioxo-2-thioxotetrahydro-5 -pyrimidinylidene)methyl]-2-furyl}benzoic acid (Cpd 30-12) and a mixture thereof, wherein the cell is in vivo in a human, and wherein the human is known, suspected, or at risk for developing cancer, a hyperproliferative disease, pulmonary fibrosis, asthma, or inflammatory bowel disease.
A method for performing time domain optical coherence tomography, comprising: splitting light from a light source by a beam splitter and thereby generating a sample beam and a reference beam sharing an optical start point; propagating the reference beam along a fixed reference optical path (222-1, 222-2, 222-3) in a forward direction only to an optical axis of a standing waveguide spectrometer and to a first end of the standing waveguide spectrometer; propagating the sample beam to a sample, wherein a portion of the sample beam is back-scattered by the sample resulting in a measurement beam; propagating the measurement beam to the optical axis of the standing waveguide spectrometer, towards a partial mirror, and from the partial mirror to a second end of the standing waveguide spectrometer; and receiving an interference signal from the standing waveguide spectrometer, wherein the interference signal is indicative of optical interference within the standing waveguide spectrometer between the reference beam and the measurement beam; and redirecting the sample beam at a scanning mirror to enable scanning of the sample in lateral directions, wherein the reference beam and the measurement beam propagate in opposite directions along the optical axis of the standing waveguide spectrometer. splitting light from a light source by a beam splitter and thereby generating a sample beam and a reference beam sharing an optical start point; propagating the reference beam along a fixed reference optical path (222-1, 222-2, 222-3) in a forward direction only to an optical axis of a standing waveguide spectrometer and to a first end of the standing waveguide spectrometer; propagating the sample beam to a sample, wherein a portion of the sample beam is back-scattered by the sample resulting in a measurement beam; propagating the measurement beam to the optical axis of the standing waveguide spectrometer, towards a partial mirror, and from the partial mirror to a second end of the standing waveguide spectrometer; and receiving an interference signal from the standing waveguide spectrometer, wherein the interference signal is indicative of optical interference within the standing waveguide spectrometer between the reference beam and the measurement beam; and redirecting the sample beam at a scanning mirror to enable scanning of the sample in lateral directions, wherein the reference beam and the measurement beam propagate in opposite directions along the optical axis of the standing waveguide spectrometer.
Refrigerated display cabinet with a closing mechanism, the display cabinet that implements a movable closing section, said closing mechanism being disposed relating to said movable closing section with the body of the display cabinet to open and close it, and said movable section having a part projected over a product arrangement area, normally fully or partially materialised in transparent material, characterised in that the closing mechanism comprises means for frontal displacement of the movable closing section from the body and means for lateral displacement of the movable closing section on either left side or right side of the body indifferently, wherein the front displacement is independent from the lateral displacement.
An integrated circuit comprising: a short-resistant pin; an adjacent pin; a short-resistant pad coupled to the short-resistant pin; an adjacent pad coupled to the adjacent pin; a short-resistant pin core logic configured to produce a first signal for the short-resistant pin; an adjacent pin core logic configured to produce a second signal for the adjacent pin; and short-resistant circuitry coupled to the short-resistant pad and the adjacent pad, the short-resistant circuitry configured to: detect a short-circuit condition between the short-resistant pin and the adjacent pin; and characterized by being further configured to prevent the second signal from being produced at the adjacent pin in response to the detection of the short-circuit condition. a short-resistant pin; an adjacent pin; a short-resistant pad coupled to the short-resistant pin; an adjacent pad coupled to the adjacent pin; a short-resistant pin core logic configured to produce a first signal for the short-resistant pin; an adjacent pin core logic configured to produce a second signal for the adjacent pin; and short-resistant circuitry coupled to the short-resistant pad and the adjacent pad, the short-resistant circuitry configured to: detect a short-circuit condition between the short-resistant pin and the adjacent pin; and characterized by being further configured to prevent the second signal from being produced at the adjacent pin in response to the detection of the short-circuit condition. detect a short-circuit condition between the short-resistant pin and the adjacent pin; and characterized by being further configured to prevent the second signal from being produced at the adjacent pin in response to the detection of the short-circuit condition.
A device for light treatment of skin, the device comprising: an interior compartment having a proximal end and a distal end an optical aperture disposed at the distal end; a laser or Broad Band Light source that produces a laser or BBL beam, the laser or BBL beam having a first optical path within the interior compartment between the proximal end and the distal end and exiting the interior compartment through the optical aperture; a camera that receives light from the optical aperture, the light having a second optical path within the interior compartment; a selectively reflective optical element disposed in the first optical path and in the second optical path; and an applicator attached to the distal end of the interior chamber, wherein the selectively reflective optical element transmits at least 70% of the laser or BBL beam incident on the selectively reflective optical element, wherein the selectively reflective optical element reflects to the camera at least 1% of incident light received from the optical aperture, and wherein the applicator is for coupling the device to a surface of skin of a patient and prevents or tracks relative movement of the surface of skin of the patient in one or more lateral directions relative to the optical aperture. an interior compartment having a proximal end and a distal end an optical aperture disposed at the distal end; a laser or Broad Band Light source that produces a laser or BBL beam, the laser or BBL beam having a first optical path within the interior compartment between the proximal end and the distal end and exiting the interior compartment through the optical aperture; a camera that receives light from the optical aperture, the light having a second optical path within the interior compartment; a selectively reflective optical element disposed in the first optical path and in the second optical path; and an applicator attached to the distal end of the interior chamber, wherein the selectively reflective optical element transmits at least 70% of the laser or BBL beam incident on the selectively reflective optical element, wherein the selectively reflective optical element reflects to the camera at least 1% of incident light received from the optical aperture, and wherein the applicator is for coupling the device to a surface of skin of a patient and prevents or tracks relative movement of the surface of skin of the patient in one or more lateral directions relative to the optical aperture.
A topical composition for treating, inhibiting or ameliorating excessive sweating, said composition comprising the following ingredients: (a) a compound having the formula: said compound having the R stereoisomeric configuration at the 2 position and the R, S or RS stereoisomeric configuration at the 1' and 3' positions, or being a mixture thereof; (b) anhydrous ethanol, present in an amount of at least 70% w/w of the composition, as a non-aqueous solvent for the compound of formula; (c) optionally, at least one gelling or viscosity-controlling ingredient; (d) isopropyl myristate; and (e) optionally, at least one additional carrier or excipient provided that said topical composition is anhydrous and comprises from about 1 % to about 25 % w/w of the compound of formula, wherein the recitation of the term "about" in relation to a stated numerical value modifies the value of the stated amount by a variance of ±20% of said stated numerical value. (a) a compound having the formula: said compound having the R stereoisomeric configuration at the 2 position and the R, S or RS stereoisomeric configuration at the 1' and 3' positions, or being a mixture thereof; (b) anhydrous ethanol, present in an amount of at least 70% w/w of the composition, as a non-aqueous solvent for the compound of formula; (c) optionally, at least one gelling or viscosity-controlling ingredient; (d) isopropyl myristate; and (e) optionally, at least one additional carrier or excipient
A composition comprising a liposome having a lipid bi-layer, the liposome containing a) an agent; b) a phospholipase A2 or phospholipase C capable of releasing the agent from the liposome in the presence of a calcium co-factor; and c) a DM-Nitrophen sequestering the calcium co-factor capable of activating the phospholipase, wherein the calcium co-factor is required for activating the phospholipase. a) an agent; b) a phospholipase A2 or phospholipase C capable of releasing the agent from the liposome in the presence of a calcium co-factor; and c) a DM-Nitrophen sequestering the calcium co-factor capable of activating the phospholipase, wherein the calcium co-factor is required for activating the phospholipase.
A ground-engaging component for an article of footwear, comprising: an outer perimeter boundary rim that at least partially defines an outer perimeter of the ground-engaging component, wherein the outer perimeter boundary rim defines an upper-facing surface and a ground-facing surface opposite the upper-facing surface, wherein the outer perimeter boundary rim defines an open space at least at a forefoot support area of the ground-engaging component, wherein a rearmost extent of the outer perimeter boundary rim is located within one of: an arch support area or a forward heel support area of the ground-engaging component, and wherein the outer perimeter boundary rim tapers inwardly at the arch support area and defines a smoothly curved rear end area at which the rearmost extent is located; and a support structure extending from the outer perimeter boundary rim and at least partially across the open space. an outer perimeter boundary rim that at least partially defines an outer perimeter of the ground-engaging component, wherein the outer perimeter boundary rim defines an upper-facing surface and a ground-facing surface opposite the upper-facing surface, wherein the outer perimeter boundary rim defines an open space at least at a forefoot support area of the ground-engaging component, wherein a rearmost extent of the outer perimeter boundary rim is located within one of: an arch support area or a forward heel support area of the ground-engaging component, and wherein the outer perimeter boundary rim tapers inwardly at the arch support area and defines a smoothly curved rear end area at which the rearmost extent is located; and a support structure extending from the outer perimeter boundary rim and at least partially across the open space.
An apparatus for reducing memory access latency in a virtual memory based system, comprising: a processor arranged to perform executable instructions; a main memory coupled, by way of a data bus, to the processor arranged to store executable instructions that are performed by the processor; a cache memory (114, 402) coupled, by way of the data bus, to the processor and the main memory arranged to store a subset of recently used instructions, wherein memory access to the cache is faster than to the main memory; a TLB for storing recently determined address translations pointed to by a TLB entry, wherein under the direction of the processor, a new address translation is moved to the TLB, which memory access is faster to the TLB than to the main memory, wherein said cache memory (114, 402) comprises a plurality of DRAM type memory devices (402-1 to 402-n), with each DRAM type memory device (402-n) including a sense amp coupled to said data bus, wherein said plurality of DRAM type memory devices (402-1 to 402-n) are virtual channel type DRAM devices and said sense amps of said DRAM type memory devices are virtual channels; and characterised in that: the address translation is distributed amongst the sense amps included in the DRAM type memory devices (402-1 to 402-n). a processor arranged to perform executable instructions; a main memory coupled, by way of a data bus, to the processor arranged to store executable instructions that are performed by the processor; a cache memory (114, 402) coupled, by way of the data bus, to the processor and the main memory arranged to store a subset of recently used instructions, wherein memory access to the cache is faster than to the main memory; a TLB for storing recently determined address translations pointed to by a TLB entry, wherein under the direction of the processor, a new address translation is moved to the TLB, which memory access is faster to the TLB than to the main memory, wherein said cache memory (114, 402) comprises a plurality of DRAM type memory devices (402-1 to 402-n), with each DRAM type memory device (402-n) including a sense amp coupled to said data bus, wherein said plurality of DRAM type memory devices (402-1 to 402-n) are virtual channel type DRAM devices and said sense amps of said DRAM type memory devices are virtual channels; and characterised in that: the address translation is distributed amongst the sense amps included in the DRAM type memory devices (402-1 to 402-n). the address translation is distributed amongst the sense amps included in the DRAM type memory devices (402-1 to 402-n).
An organic-inorganic composite filler with an average particle size of 3 to 100 μm, comprising: inorganic agglomerated particles comprising agglomerates of inorganic primary particles with an average particle size of 10 to 1,000 nm; an organic resin phase with which a surface of each inorganic primary particle is coated and with which the inorganic primary particles are bonded together; and intra-agglomerate voids that are formed between parts of the organic resin phase, with which the surface of each inorganic primary particle is coated, and have a pore volume of 0.01 to 0.30 cm 3 /g as measured by mercury intrusion porosimetry, wherein the pore volume corresponds to the volume of pores with pore sizes in the range of 1 to 500 nm. inorganic agglomerated particles comprising agglomerates of inorganic primary particles with an average particle size of 10 to 1,000 nm; an organic resin phase with which a surface of each inorganic primary particle is coated and with which the inorganic primary particles are bonded together; and intra-agglomerate voids that are formed between parts of the organic resin phase, with which the surface of each inorganic primary particle is coated, and have a pore volume of 0.01 to 0.30 cm 3 /g as measured by mercury intrusion porosimetry, wherein the pore volume corresponds to the volume of pores with pore sizes in the range of 1 to 500 nm.
A power supply unit for supplying energy to a digital information bus system via a voltage output, wherein the power supply unit comprises: - a first voltage input to which a first voltage is supplied and - a current limiting circuit connected between the first voltage input and the voltage output, characterised by - a control circuit for controlling a first switching element arranged between the first voltage input and the current limiting circuit for switchably connecting the first voltage input to the current limiting circuit and - a second voltage input, to which a second voltage (Uh) is supplied, wherein the control circuit is configured to record the output voltage (Ub) at the voltage output and, if a determinable first threshold value Us1 is not reached, to interrupt the connection of the first voltage input to the current limiting circuit by controlling the first switching element, and to re-establish it if a second threshold value Us2 is exceeded, wherein the second voltage input is configured to supply the second voltage (Uh) to the current limiting circuit during the duration of interruption by the first switching element, wherein the second voltage (Uh) is lower than the first voltage. - a first voltage input to which a first voltage is supplied and - a current limiting circuit connected between the first voltage input and the voltage output, - a control circuit for controlling a first switching element arranged between the first voltage input and the current limiting circuit for switchably connecting the first voltage input to the current limiting circuit and - a second voltage input, to which a second voltage (Uh) is supplied,
Winding mechanism of a timepiece comprising at least one first power accumulator arranged such that it supplies a first mechanism with power and a second power accumulator arranged such that it supplies a second mechanism with power, said winding mechanism including a winding stem, a winding pinion and a sliding pinion borne by said winding stem and having straight toothings facing one another, arranged so as to allow the winding pinion to be driven by the sliding pinion in the two directions of rotation of the winding stem, said winding stem and the sliding pinion occupying the same axial winding position, characterised in that said winding stem is housed inside a plate such that the winding pinion is operational on either side of the winding stem relative to the plate and in that the winding mechanism comprises a first and a second coupling/uncoupling devices (16, 18) disposed on either side of the winding stem relative to the plate, cooperating with the winding pinion and arranged such that one of said first and second coupling/uncoupling devices (16, 18) occupies a coupling position for coupling the winding pinion and the first power accumulator, while the other of the first and second coupling/uncoupling devices (16, 18) occupies an uncoupling position for uncoupling the second power accumulator when the winding stem is turned in one direction, and occupies an uncoupling position for uncoupling the first power accumulator, while the other of the first and second coupling/uncoupling devices (16, 18) occupies a coupling position for coupling the winding pinion and the second power accumulator when the winding stem is turned in the other direction.
A polyester elastomer resin composition which contains; a thermoplastic polyester elastomer prepared by bonding a hard segment and a soft segment, wherein the hard segment comprises a polyester constituted from an aromatic dicarboxylic acid and an aliphatic and/or alicyclic diol(s) as constituting ingredients, and wherein the soft segment is at least one member selected from a group consisting of an aliphatic polyether, an aliphatic polyester and an aliphatic polycarbonate; an alicyclic polycarbodiimide compound and/or an aliphatic polycarbodiimide compound; and a polyamide resin having an amine value of 50 to 2000 eq/t in such a ratio that is in 0.1 to 5 part(s) by mass and is in 0.1 to 10 part(s) by mass to 100 parts by mass of, characterized in that the polyester elastomer resin composition has an acid value which is more than 5 eq/t and not more than 20 eq/t, wherein the amine value and the acid value are determined as indicated in the description.