mhurhangee/ep-ind-claims huggingface dataset:
A method for preparation of a high concentration liquid formulation of an antibody having a concentration C H of the antibody, comprising the steps of: a. providing a solution containing the antibody in a starting concentration C S and histidine; b. ultrafiltering the solution of step (a) in order to obtain a solution having an intermediate concentration C I of the antibody, wherein C I is up to 285 mg/mL; and c. diluting the solution of step (b) with a buffer solution comprising histidine, a polysorbate and sorbitol to a concentration C H of the antibody in order to obtain the high concentration liquid formulation, having a pH value of 5.5±0.3, wherein C H is 160-220 mg/mL and the antibody is veltuzumab, the concentration of histidine is in the range of 20 to 40 mM, the polysorbate is polysorbate 20 with a concentration in the range of 0.1 to 0.3 mg/mL, and a concentration of sorbitol of 220 mM. a. providing a solution containing the antibody in a starting concentration C S and histidine; b. ultrafiltering the solution of step (a) in order to obtain a solution having an intermediate concentration C I of the antibody, wherein C I is up to 285 mg/mL; and c. diluting the solution of step (b) with a buffer solution comprising histidine, a polysorbate and sorbitol to a concentration C H of the antibody in order to obtain the high concentration liquid formulation, having a pH value of 5.5±0.3, wherein C H is 160-220 mg/mL and the antibody is veltuzumab, the concentration of histidine is in the range of 20 to 40 mM, the polysorbate is polysorbate 20 with a concentration in the range of 0.1 to 0.3 mg/mL, and a concentration of sorbitol of 220 mM.
A quick mounting holder structure for sinking mechanical extension device of functional sofa, comprising a mounting support; a stretchable component; a backrest component; and a main body; wherein the mounting support, the stretchable component, and the backrest component are rotatably installed on the main body; characterized in that: the mounting support includes a crossbeam and at least one mounting piece; the crossbeam includes a main board and a side panel; the side panel is fixed on the main board and is perpendicular to said main board; the at least one mounting piece is fixed on the side panel; the at least one mounting piece is perpendicular to the side panel; and at least one fixing hole and at least one mounting hole are provided on the at least mounting piece; wherein the at least one mounting piece is made by bending the side panel; and an opening is formed between the at least one mounting piece and the side panel. a mounting support; a stretchable component; a backrest component; and a main body; wherein the mounting support, the stretchable component, and the backrest component are rotatably installed on the main body; characterized in that: the mounting support includes a crossbeam and at least one mounting piece; the crossbeam includes a main board and a side panel; the side panel is fixed on the main board and is perpendicular to said main board; the at least one mounting piece is fixed on the side panel; the at least one mounting piece is perpendicular to the side panel; and at least one fixing hole and at least one mounting hole are provided on the at least mounting piece; wherein the at least one mounting piece is made by bending the side panel; and an opening is formed between the at least one mounting piece and the side panel.
System for locking and/or unlocking an object, such as a power battery of a drive engine of an electric or hybrid motor vehicle, under a structure such as a chassis of the vehicle, the system comprising a plurality of locks ensuring the fixing of the object under the structure, the system being characterized in that the locks are secured to the object and/or the structure and each comprising on the one hand a hook configured to draw the object in the direction of the structure by compressing a resiliently deformable means inserted between the object and the structure and to support the object relative to the structure at the end of the drawing travel, and on the other hand a transmission device (21, 22, 24) driving the hook during the drawing travel and configured to be actuated by an actuation tool that is separate from the structure and the object.
An in vitro cell population, comprising mammalian, preferably human, neuronal cells, at least about 80% the neuronal cells being positive for both LIM homeobox transcription factor 1 and forkhead box A2 (FoxA2) expression, wherein the cells are transgenic and comprise a screenable or selectable marker under the control of a pan-neural promoter.
(Amended) A mental disorder analysis apparatus, comprising: a storage portion in which sleep electroencephalogram information, which is information on electroencephalograms during sleep of a test subject, is stored; an analyzing portion which is configured to perform analysis regarding presence or absence of a mental disorder using the sleep electroencephalogram information stored in the storage portion; and wherein, as the analysis, the analyzing portion is configured to acquire information indicating an appearance rate of α waves contained in sleep electroencephalogram information in a non-REM sleep period, in the sleep electroencephalogram information, characterised in that the analysis portion is further configured to determine the presence or absence of a mental disorder according to the information; an output portion which is configured to output a result of the determination regarding the presence or absence of a mental disorder performed by the analyzing portion, wherein said mental disorder is depression, wherein the analyzing portion is configured to detect spindle waves in an α band in sleep electroencephalogram information in a non-REM sleep period, in the sleep electroencephalogram information, and to determine that depression is present in a case where an appearance rate of the detected spindle waves exceeds a predetermined threshold value. a storage portion in which sleep electroencephalogram information, which is information on electroencephalograms during sleep of a test subject, is stored; an analyzing portion which is configured to perform analysis regarding presence or absence of a mental disorder using the sleep electroencephalogram information stored in the storage portion; and wherein, as the analysis, the analyzing portion is configured to acquire information indicating an appearance rate of α waves contained in sleep electroencephalogram information in a non-REM sleep period, in the sleep electroencephalogram information, characterised in that the analysis portion is further configured to determine the presence or absence of a mental disorder according to the information; an output portion which is configured to output a result of the determination regarding the presence or absence of a mental disorder performed by the analyzing portion, wherein said mental disorder is depression, wherein the analyzing portion is configured to detect spindle waves in an α band in sleep electroencephalogram information in a non-REM sleep period, in the sleep electroencephalogram information, and to determine that depression is present in a case where an appearance rate of the detected spindle waves exceeds a predetermined threshold value.
A method for setting femto cell identification information for handover by a femto cell Base Station, BS, in a wireless communication system, the method comprising: setting a start frequency of a beacon signal to be different from a start frequency of a neighbor femto cell, a femto cell of the femto cell BS and the neighbor femto cell shares frequencies of the beacon signal for frequency hopping; sequentially hopping a frequency of the beacon signal according to a frequency hopping scheme beginning from the start frequency; and setting, by the femto cell BS, new femto cell identification information of the femto cell which is distinguishable from a femto cell identification information of the neighbor femto cell and which is based on the frequency hopping scheme and the start frequency. setting a start frequency of a beacon signal to be different from a start frequency of a neighbor femto cell, a femto cell of the femto cell BS and the neighbor femto cell shares frequencies of the beacon signal for frequency hopping; sequentially hopping a frequency of the beacon signal according to a frequency hopping scheme beginning from the start frequency; and setting, by the femto cell BS, new femto cell identification information of the femto cell which is distinguishable from a femto cell identification information of the neighbor femto cell and which is based on the frequency hopping scheme and the start frequency.
A method for producing a large container, comprising: an injection step of injection molding a polyethylene terephthalate resin to form a preform; an intermediate molding step of blow molding the preform to form a primary blow molded product having a size larger than that of the large container, heating the primary blow molded product, and shrinking the primary blow molded product to a size smaller than that of the large container to form an intermediate molded product; and a final molding step of blow molding the intermediate molded product within a final blow mold heated to a predetermined temperature to obtain the large container of a predetermined shape, characterized in that the preform has a longitudinal axis length longer than that of the large container which is a final molded product. an injection step of injection molding a polyethylene terephthalate resin to form a preform; an intermediate molding step of blow molding the preform to form a primary blow molded product having a size larger than that of the large container, heating the primary blow molded product, and shrinking the primary blow molded product to a size smaller than that of the large container to form an intermediate molded product; and a final molding step of blow molding the intermediate molded product within a final blow mold heated to a predetermined temperature to obtain the large container of a predetermined shape, characterized in that the preform has a longitudinal axis length longer than that of the large container which is a final molded product.
An apparatus comprising: a firing furnace comprising: a heating chamber configured to fire a metallization layer of photovoltaic devices and a cooling chamber configured to cool the photovoltaic devices that have been heated by the heating chamber; wherein the cooling chamber comprises lights to light anneal the photovoltaic devices to reduce light induced degradation as the photovoltaic devices are cooled in the cooling chamber; and wherein the cooling chamber of the firing furnace is configured to use residual heat from heating performed in the heating chamber of the firing furnace as heat for the light annealing of the photovoltaic devices; and wherein light annealing is not performed in the heating chamber of the firing furnace, characterized in that the lights comprise light emitting diodes (LEDs) mounted to a water-cooled plate. a heating chamber configured to fire a metallization layer of photovoltaic devices and a cooling chamber configured to cool the photovoltaic devices that have been heated by the heating chamber; wherein the cooling chamber comprises lights to light anneal the photovoltaic devices to reduce light induced degradation as the photovoltaic devices are cooled in the cooling chamber; and wherein the cooling chamber of the firing furnace is configured to use residual heat from heating performed in the heating chamber of the firing furnace as heat for the light annealing of the photovoltaic devices; and wherein light annealing is not performed in the heating chamber of the firing furnace, characterized in that the lights comprise light emitting diodes (LEDs) mounted to a water-cooled plate.
A method for producing a metal/ceramic bonding substrate, the method comprising the steps of: arranging a ceramic substrate in a mold; putting the mold in a furnace; lowering an oxygen concentration to 25 ppm or less and a dew point to -45 °C or lower in the furnace; injecting a molten metal of aluminum into the mold so as to allow the molten metal to contact one side of the ceramic substrate; and cooling and solidifying the molten metal in the mold to form an aluminum plate on the one side of the ceramic substrate to bond the aluminum plate directly to the ceramic substrate. arranging a ceramic substrate in a mold; putting the mold in a furnace; lowering an oxygen concentration to 25 ppm or less and a dew point to -45 °C or lower in the furnace; injecting a molten metal of aluminum into the mold so as to allow the molten metal to contact one side of the ceramic substrate; and cooling and solidifying the molten metal in the mold to form an aluminum plate on the one side of the ceramic substrate to bond the aluminum plate directly to the ceramic substrate.
A diagnostic apparatus for a rotational angle sensor that outputs two correlated signals, corresponding to a rotational angle, characterized in that the diagnostic apparatus determines whether or not a failure has occurred in the rotational angle sensor based on whether or not a numerical value obtained from the two correlated signals is within a predetermined range, and in a case in which the diagnostic apparatus determines that the failure has occurred in the rotational angle sensor, the diagnostic apparatus cancels the determination that the failure has occurred in the rotational angle sensor, when the numerical value obtained after the diagnostic apparatus has determined the failure is within the predetermined range and the rotational angle obtained from the two correlated signals is an angle that cannot be recognized to be 0°, 90°, 180°, or 270°.
A stabilizer device for arrangement between a first railcar body and a second railcar body of a vehicle, in particular a roll stabilizer for arrangement in the roof region between the railcar bodies (10, 11) of a rail vehicle, having a first fastening member for arrangement at the first railcar body and a second fastening member for arrangement at the second railcar body, further having a coupling element by which the two fastening members (12, 13) are coupled to one another, wherein the fastening members (12, 13) have a flange part for arrangement at the railcar body (10, 11) and a coupling part for receiving the coupling element, wherein the coupling element is movably linked to the respective coupling part of the fastening members (12, 13) by means of a coupling joint, and wherein the flange part and the coupling part are connected to one another by means of a pivot joint, wherein the pivot joint has a damping means, and wherein the damping means comprises at least one elastic member, characterized in that the pivot joint has a sleeve member and an axle member, with the elastic member forming the damping means being introduced between the sleeve member and the axle member.
A robot configured for interaction with a user, comprising: a robot body comprising a torso and, attached thereto, a head and at least one appendage; a plurality of identical navigators, disposed in different locations on the robot, for receiving input from a user; and a processor for processing the input and, based thereon, controlling an action of the at least one appendage, characterized in that the navigators and processor are collectively configured such that a series of user inputs provided via multiple of the navigators causes the same action as the series of user inputs provided via a single one of the navigators. a robot body comprising a torso and, attached thereto, a head and at least one appendage; a plurality of identical navigators, disposed in different locations on the robot, for receiving input from a user; and a processor for processing the input and, based thereon, controlling an action of the at least one appendage,
A geared architecture for a gas turbine engine comprising: a fan shaft; a frame which supports said fan shaft, said frame defines a frame transverse stiffness (Kframe BEND); a gear system which drives said fan shaft; a flexible support which at least partially supports said gear system; and an input coupling to said gear system, characterised in that: said input coupling defines an input coupling transverse stiffness (KIC BEND) with respect to said frame transverse stiffness (Kframe BEND) of less than 11% of said frame transverse stiffness (Kframe BEND); and said flexible support defines a flexible support transverse stiffness (KFS BEND) with respect to said frame transverse stiffness (Kframe BEND) of less than 11% of said frame transverse stiffness (Kframe BEND). a fan shaft; a frame which supports said fan shaft, said frame defines a frame transverse stiffness (Kframe BEND); a gear system which drives said fan shaft; a flexible support which at least partially supports said gear system; and an input coupling to said gear system, said input coupling defines an input coupling transverse stiffness (KIC BEND) with respect to said frame transverse stiffness (Kframe BEND) of less than 11% of said frame transverse stiffness (Kframe BEND); and said flexible support defines a flexible support transverse stiffness (KFS BEND) with respect to said frame transverse stiffness (Kframe BEND) of less than 11% of said frame transverse stiffness (Kframe BEND).
A method of making a panel assembly, the method comprising the steps of: a. forming a thermoplastic panel, b. placing a thermoset portion into a pocket in a mold, c. placing an attachment member into the pocket in the mold, d. positioning the thermoplastic panel in the mold, e. cooling the thermoplastic panel while heating the thermoset portion to flow at least a portion of the thermoset portion into openings defined in the thermoplastic panel, and f. cooling the panel assembly so that the thermoset portion hardens, thereby securing the attachment member to the thermoplastic panel. a. forming a thermoplastic panel, b. placing a thermoset portion into a pocket in a mold, c. placing an attachment member into the pocket in the mold, d. positioning the thermoplastic panel in the mold, e. cooling the thermoplastic panel while heating the thermoset portion to flow at least a portion of the thermoset portion into openings defined in the thermoplastic panel, and f. cooling the panel assembly so that the thermoset portion hardens, thereby securing the attachment member to the thermoplastic panel.
A circuit breaker, comprising: a communication module configured to receive protection settings and breaker information from a trip unit coupled to said communication module; a non-transitory memory device configured to store the protection settings and the breaker information associated with said circuit breaker; characterized in a memory controller configured to cause the protection settings and the breaker information received to be written to said non-transitory memory device; and the communication module is adapted to receive the protection settings and the breaker information upon a triggering event which comprises powering-on the trip unit. a communication module configured to receive protection settings and breaker information from a trip unit coupled to said communication module; a non-transitory memory device configured to store the protection settings and the breaker information associated with said circuit breaker; a memory controller configured to cause the protection settings and the breaker information received to be written to said non-transitory memory device; and the communication module is adapted to receive the protection settings and the breaker information upon a triggering event which comprises powering-on the trip unit.
Device for the automatic determination of characteristics on textile test material, such as yarns, rovings and slivers, containing a path, through which the test material is movable in its longitudinal direction, at least one measuring element (4, 5, 6) arranged along the path for measuring a parameter of the test material, a feed mechanism for generating a longitudinal movement of the test material in the path, a supply device for supplying the test material into the path, and means for removing undesired particles, such as loose fibres, dirt or dust, characterised in that the means for removing undesired particles contain a plurality of suction elements (14 to 18, 31, 32, 40, 41) which are arranged along the path and spaced apart from one another and are configured for generating an underpressure, by means of which the undesired particles are suckable from the path.
A wind turbine rotor blade comprising at least a first rotor blade segment and a second rotor blade segment connected by means of a connecting interface, which connecting interface comprises - a plurality of bores formed in a connecting face (21F, 22F) of each rotor blade segment (21, 22), each bore extending in a longitudinal direction of the rotor blade and terminating in a cavity dimensioned to accommodate a threaded nut; - a threaded nut arranged in each of the plurality of cavities; and - a plurality of double-end stud bolts, wherein a double-end stud bolt comprises a shaped portion formed between a first threaded end and a second threaded end, which shaped portion is shaped to engage with a bolt tightening means; and wherein the first threaded end of each double-end stud bolt is screwed into a threaded nut held in a cavity of the first rotor blade segment, and the second threaded end of each double-end stud bolt is screwed into a threaded nut held in a cavity of the second rotor blade segment. - a plurality of bores formed in a connecting face (21F, 22F) of each rotor blade segment (21, 22), each bore extending in a longitudinal direction of the rotor blade and terminating in a cavity dimensioned to accommodate a threaded nut; - a threaded nut arranged in each of the plurality of cavities; and - a plurality of double-end stud bolts, wherein a double-end stud bolt comprises a shaped portion formed between a first threaded end and a second threaded end, which shaped portion is shaped to engage with a bolt tightening means; and wherein the first threaded end of each double-end stud bolt is screwed into a threaded nut held in a cavity of the first rotor blade segment, and the second threaded end of each double-end stud bolt is screwed into a threaded nut held in a cavity of the second rotor blade segment.
A medical support and compression stocking, comprising a woven- or knitted-fabric-type base element that is substantially tubular, which is designed in such manner that it can be pulled over the lower leg of the wearer, at least one air chamber that can be filled with air, wherein the at least one air chamber is designed in a tubular shape along the length of the support and compression stocking, characterized in that the woven- or knitted-fabric-type base element comprises at least one tensioning device, namely at least one zipper or at least one velcro fastener, and wherein the walls of the at least one air chamber are designed in such manner that they comprise at least a defined breathability to allow the body moisture to diffuse, wherein the water vapor transfer resistance Ret shall not exceed 20 m 2 Pa/W and wherein the walls of the at least one air chamber comprise airtight membranes.