A method of producing a transdermal absorption sheet comprising: an apparatus preparing step of preparing a mold (13, 113) having needle-like recessed portions and having an angle of 120° or more and 160° or less inside the mold (13, 113), the angle being formed between a flat portion of a surface and an inlet portion of the needle-like recessed portion, and a liquid feeding apparatus including a slit-shaped opening portion (34C, 134C, 234C, 334C, 434C) formed at a nozzle tip end portion and a lip land portion; a filling step of filling the needle-like recessed portions with a solution by feeding the solution to the mold (13, 113) from the liquid feeding apparatus and moving the liquid feeding apparatus while, when a travelling direction of the liquid feeding apparatus is set to a primary side and a direction opposite to the travelling direction is set to a secondary side, bringing at least a rear end of the lip land portion (34B, 134B, 234B, 334B, 434B) on the secondary side into contact with the mold; and a sheet portion forming step of forming needle portions and a sheet portion using a polymer solution, characterized in that in the filling step, when the rear end of the lip land portion (34B, 134B, 234B, 334B, 434B) on the secondary side of the liquid feeding apparatus matches with a secondary side inlet of the needle-like recessed portion, the shortest length of a distance from a primary side inlet of the needle-like recessed portion to the lip land portion (34B, 134B, 234B, 334B, 434B) on the secondary side or a wall surface (34D, 134D, 234D, 334D, 434D) of a secondary side block of the opening portion (34C, 134C, 234C, 334C, 434C) of the liquid feeding apparatus is 220 μm or less. an apparatus preparing step of preparing a mold (13, 113) having needle-like recessed portions and having an angle of 120° or more and 160° or less inside the mold (13, 113), the angle being formed between a flat portion of a surface and an inlet portion of the needle-like recessed portion, and a liquid feeding apparatus including a slit-shaped opening portion (34C, 134C, 234C, 334C, 434C) formed at a nozzle tip end portion and a lip land portion; a filling step of filling the needle-like recessed portions with a solution by feeding the solution to the mold (13, 113) from the liquid feeding apparatus and moving the liquid feeding apparatus while, when a travelling direction of the liquid feeding apparatus is set to a primary side and a direction opposite to the travelling direction is set to a secondary side, bringing at least a rear end of the lip land portion (34B, 134B, 234B, 334B, 434B) on the secondary side into contact with the mold; and a sheet portion forming step of forming needle portions and a sheet portion using a polymer solution, characterized in that in the filling step, when the rear end of the lip land portion (34B, 134B, 234B, 334B, 434B) on the secondary side of the liquid feeding apparatus matches with a secondary side inlet of the needle-like recessed portion, the shortest length of a distance from a primary side inlet of the needle-like recessed portion to the lip land portion (34B, 134B, 234B, 334B, 434B) on the secondary side or a wall surface (34D, 134D, 234D, 334D, 434D) of a secondary side block of the opening portion (34C, 134C, 234C, 334C, 434C) of the liquid feeding apparatus is 220 μm or less.