mhurhangee/ep-ind-claims huggingface dataset:
A compound of formula, wherein R 1 is wherein R 4 is cyano; R 4a is H or deuterium; R 4b is H or deuterium; R 2 is 1,2,3,4-tetrahydroisoquinolinyl which is unsubstituted or substituted by hydroxy; 5,6,7,8-tetrahydro-1,6-naphthyridiny1;5,6,7,8-tetrahydro-2,6-naphthyridinyl which is unsubstituted or substituted by C 1-6 alkyl;5,6,7,8-tetrahydro-2,7-naphthyridinyl; or 6,7-dihydro-5H-pyrrolo[3,4-b]pyridinyl which is unsubstituted or substituted by C 1-6 alkyl; R 3 is C 1-6 alkyl; L is or a pharmaceutically acceptable salt thereof. R 1 is wherein R 4 is cyano; R 4a is H or deuterium; R 4b is H or deuterium; R 2 is 1,2,3,4-tetrahydroisoquinolinyl which is unsubstituted or substituted by hydroxy; 5,6,7,8-tetrahydro-1,6-naphthyridiny1;5,6,7,8-tetrahydro-2,6-naphthyridinyl which is unsubstituted or substituted by C 1-6 alkyl;5,6,7,8-tetrahydro-2,7-naphthyridinyl; or 6,7-dihydro-5H-pyrrolo[3,4-b]pyridinyl which is unsubstituted or substituted by C 1-6 alkyl; R 3 is C 1-6 alkyl; L is or a pharmaceutically acceptable salt thereof.
A method for the display of an image in a display area, the method comprising: requesting, from a server, a scrambled image file using an image identifier, the scrambled image file containing the image in a scrambled form; receiving the scrambled image file; dividing the scrambled image file into a plurality of image fragments, the image fragments having a first order within the scrambled image file, wherein dividing the scrambled image file into a plurality of image fragments is defined by a slicing map which is generated based on the image identifier, the slicing map defining the boundary between image fragments within the scrambled image file, each image fragment having a shape and the slicing map being generated such that the shape of at least some of the image fragments are different to the shape of at least some of the other image fragments; and rendering the image fragments on to the display area in a second order derived from the image identifier to display the image in unscrambled form, wherein the image identifier is used as a scrambling key to generate the second order of the image fragments. requesting, from a server, a scrambled image file using an image identifier, the scrambled image file containing the image in a scrambled form; receiving the scrambled image file; dividing the scrambled image file into a plurality of image fragments, the image fragments having a first order within the scrambled image file, wherein dividing the scrambled image file into a plurality of image fragments is defined by a slicing map which is generated based on the image identifier, the slicing map defining the boundary between image fragments within the scrambled image file, each image fragment having a shape and the slicing map being generated such that the shape of at least some of the image fragments are different to the shape of at least some of the other image fragments; and rendering the image fragments on to the display area in a second order derived from the image identifier to display the image in unscrambled form, wherein the image identifier is used as a scrambling key to generate the second order of the image fragments.
An agent, suitable for applying to mucosa, for use in the prevention or treatment of corneal epithelial layer disorders containing glycosaminoglycan into which a hydrophobic group is introduced via a binding chain, as an active ingredient, wherein the glycosaminoglycan is hyaluronic acid or salt thereof, the binding chain is -CONH-, or -COO-, the hydrophobic group is arylalkenyl group, the glycosaminoglycan into which a hydrophobic group is introduced via a binding chain further includes a spacer chain between the binding chain and the hydrophobic group, wherein the spacer chain further includes a binding chain at a hydrophobic group side, and the spacer chain further having the binding chain at the hydrophobic group side is -COO-(CH 2) m -, -COO-(CH 2)-(OCH 2) n -, -CONH-(CH 2) m, or -CONH-(CH 2)-(OCH 2) n -, wherein m and n represent integers of 1 to 18.
Method for adjusting the speed of at least one vehicle (V1, V2, V3, V4, V5) belonging to a first set of at least two autonomous vehicles moving in a coordinated manner on an itinerary, comprising the following steps implemented in an entity for managing a telecommunications infrastructure which is able to transmit a message to the at least one vehicle: - acquiring event information (Mf) originating from a vehicle in the first set and relating to an event occurring on said itinerary, said information comprising an identifier of the vehicle associated with an identifier of the first set, - identifying at least one target vehicle (V1, V2, V3, V4, V5) and at least one second set of vehicles in accordance with the transmitting vehicle determined on the basis of the identifier of the vehicle transmitting the acquired event information, - determining an instruction to adjust the speed of the at least one target vehicle (V1, V2, V3, V4, V5) in accordance with the acquired event information, - transmitting, to the at least one identified vehicle (V1, V2, V3, V4, V5) and to a second entity for managing a telecommunications infrastructure in charge of the at least one second set, said instruction to adjust the speed (Mr, Mr1, Mr2) of the at least one target vehicle (V1, V2, V3, V4, V5). - acquiring event information (Mf) originating from a vehicle in the first set and relating to an event occurring on said itinerary, said information comprising an identifier of the vehicle associated with an identifier of the first set, - identifying at least one target vehicle (V1, V2, V3, V4, V5) and at least one second set of vehicles in accordance with the transmitting vehicle determined on the basis of the identifier of the vehicle transmitting the acquired event information, - determining an instruction to adjust the speed of the at least one target vehicle (V1, V2, V3, V4, V5) in accordance with the acquired event information, - transmitting, to the at least one identified vehicle (V1, V2, V3, V4, V5) and to a second entity for managing a telecommunications infrastructure in charge of the at least one second set, said instruction to adjust the speed (Mr, Mr1, Mr2) of the at least one target vehicle (V1, V2, V3, V4, V5).
A system comprising: a controller configured to control power plant operations; a heat recovery steam generator, HRSG, monitor communicatively coupled to the controller and configured to receive inputs corresponding to the power plant operations; and an HRSG life prediction model configured to predict a remaining operating life for an HRSG component, wherein the HRSG monitor uses the HRSG life prediction model and the inputs to communicate a control action to the controller, wherein the HRSG life prediction model comprises a pre-calculated differential temperature curve model configured to model stress as a first function of a temperature difference over time. a controller configured to control power plant operations; a heat recovery steam generator, HRSG, monitor communicatively coupled to the controller and configured to receive inputs corresponding to the power plant operations; and an HRSG life prediction model configured to predict a remaining operating life for an HRSG component, wherein the HRSG monitor uses the HRSG life prediction model and the inputs to communicate a control action to the controller, wherein the HRSG life prediction model comprises a pre-calculated differential temperature curve model configured to model stress as a first function of a temperature difference over time.
A composition comprising atropine for use in a method of treatment of myopia in a child, wherein the composition comprises 0.0001% to 5% atropine by weight and is delivered to an eye of the child as a micro-dose stream of droplets by once-a-day dosing, wherein the micro-dose stream of droplets: (i) is from 3 microliters to less than 10 microliters; (ii) is generated via a piezoelectric droplet delivery device; (iii) has an average ejected droplet diameter of 20 microns to 100 microns; and (iv) has an average initial ejecting velocity of at least 3 m/s to about 4 m/s. (i) is from 3 microliters to less than 10 microliters; (ii) is generated via a piezoelectric droplet delivery device; (iii) has an average ejected droplet diameter of 20 microns to 100 microns; and (iv) has an average initial ejecting velocity of at least 3 m/s to about 4 m/s.
A visible light photocatalyst coating, comprising a metal oxide and an auxiliary light absorbent in the presence of an organic contaminant that absorbs at least some visible light, wherein visible light catalyzes degradation of the organic contaminant, and wherein the metal oxide is a nanoparticle or microparticle or a film that contains crystallites of less than 50 nm, wherein the auxiliary light absorbent is a dye having an absorbance of light in at least a portion of the visible spectrum, wherein the auxiliary light absorbent comprises polyhydroxy fullerene, fullerenes, carbon onions, graphene, or any combination thereof, wherein the organic contaminant is a microbe or an organic pollutant.
A method for data processing, wherein, during a training-phase of a customer premises equipment, a central office reports a transmit power to the customer premises equipment, characterized in that the central office conveys data towards the customer premises equipment with a reduced transmission power compared to the reported transmission power at at least one frequency, and the customer premises equipment determines a signal-to-noise ratio based on the data conveyed.
A wall cupboard holder for wall cupboards, comprising: - a box-shaped body made of plastic material comprising in its turn: an upper side - destined for being buffered against a top of the cupboard - a rear side and a front side - opposite to said rear side - destined to be buffered against the cover of the cupboard - - an arm which extends externally from said box-shaped body - a hook with a hooking point situated at a free end of said arm - a regulation mechanism for regulating the positions in depth and height of said hook contained in said box-shaped body - exactly three fixing means (21, 121, 221) of said box-shaped body to be fixed to a shoulder of said cupboard - a first and second fixing means (21, 121) being engaged with two respective interspaced points lying on a first plane, - a third fixing means being engaged with a third point lying on a second plane - said arm being positioned between said first and second plane (P1, P3), said first and second plane (P1, P3) being respectively positioned above and below the hooking point - said first plane being parallel to said upper side of the wall cupboard holder - said third fixing means lies with the first fixing means on a third plane which is parallel to the front side, wherein said third lower fixing means is positioned close to a front side of the wall cupboard holder. - a box-shaped body made of plastic material comprising in its turn: an upper side - destined for being buffered against a top of the cupboard - a rear side and a front side - opposite to said rear side - destined to be buffered against the cover of the cupboard - - an arm which extends externally from said box-shaped body - a hook with a hooking point situated at a free end of said arm - a regulation mechanism for regulating the positions in depth and height of said hook contained in said box-shaped body - exactly three fixing means (21, 121, 221) of said box-shaped body to be fixed to a shoulder of said cupboard - a first and second fixing means (21, 121) being engaged with two respective interspaced points lying on a first plane, - a third fixing means being engaged with a third point lying on a second plane - said arm being positioned between said first and second plane (P1, P3), said first and second plane (P1, P3) being respectively positioned above and below the hooking point - said first plane being parallel to said upper side of the wall cupboard holder - said third fixing means lies with the first fixing means on a third plane which is parallel to the front side, wherein
A method of manufacturing a product having a complex shape by using at least one jig and at least one mandrel, the method comprising: a preparation step of preparing a prepreg sheet and a cylindrical first mandrel around which the prepreg sheet is wound; a first rolling step of forming a first stacking surface by winding the prepreg sheet around the first mandrel; a first heating step of taping and heating the first stacking surface; a second mandrel preparation step of removing the tape and locating a second mandrel on an outer circumferential surface of the first stacking surface; a second rolling step of forming a second stacking surface by winding the first stacking surface and the second mandrel with a prepreg sheet; a second heating step of taping and heating the second stacking surface; and a core removal step of removing the first mandrel and the second mandrel wherein the second mandrel is a jig having one of various shapes. a preparation step of preparing a prepreg sheet and a cylindrical first mandrel around which the prepreg sheet is wound; a first rolling step of forming a first stacking surface by winding the prepreg sheet around the first mandrel; a first heating step of taping and heating the first stacking surface; a second mandrel preparation step of removing the tape and locating a second mandrel on an outer circumferential surface of the first stacking surface; a second rolling step of forming a second stacking surface by winding the first stacking surface and the second mandrel with a prepreg sheet; a second heating step of taping and heating the second stacking surface; and a core removal step of removing the first mandrel and the second mandrel wherein the second mandrel is a jig having one of various shapes.
A method of communicating capability information operable at a device, comprising: communicating with another device over a carrier utilizing a half duplex mode or a same frequency full duplex mode; and transmitting a capability indication indicative of the capability of the device to support a plurality of features based on whether the device is operating in the half duplex mode or the same frequency duplex mode, wherein the capability indication comprises a message having a number of bits less than configurations of the plurality of supported features, to indicate one or more features of the plurality of features are disabled or enabled at the device based on whether the device is communicating in the half duplex mode or the same frequency full duplex mode, characterized in that the capability indication comprises 3 bits that are utilized to signal more than 8 configurations of the plurality of supported features, wherein the capability indication is configured not to individually indicate the support of the plurality of features. communicating with another device over a carrier utilizing a half duplex mode or a same frequency full duplex mode; and transmitting a capability indication indicative of the capability of the device to support a plurality of features based on whether the device is operating in the half duplex mode or the same frequency duplex mode, wherein the capability indication comprises a message having a number of bits less than configurations of the plurality of supported features, to indicate one or more features of the plurality of features are disabled or enabled at the device based on whether the device is communicating in the half duplex mode or the same frequency full duplex mode, characterized in that the capability indication comprises 3 bits that are utilized to signal more than 8 configurations of the plurality of supported features, wherein the capability indication is configured not to individually indicate the support of the plurality of features.
Method for the production of composite rods for smoking articles, comprising the steps of: - providing a plurality of rod segments (A, B), and - wrapping a web of wrapping material around said segments, and causing it to adhere thereto with the aid of adhesive material (G, G') interposed between said web and said segments (A, B), characterized in that before wrapping said web around said segments (A, B) adhesive material (G') is applied directly on the surface of at least some of said segments (A, B). - providing a plurality of rod segments (A, B), and - wrapping a web of wrapping material around said segments, and causing it to adhere thereto with the aid of adhesive material (G, G') interposed between said web and said segments (A, B),
A method of diagnosing and/or predicting erosive joint destruction in rheumatoid arthritis comprising determining in a sample obtained from an individual independent of HLA-DR shared epitope the presence of at least one nucleic acid sequence selected from the group consisting of (a) a nucleic acid sequence encoding an IL-4 receptor (IL-4R) which contains a mutation in position 465 of the nucleotide sequence of the wild-type IL4R as shown in SEQ ID NO: 1, whereby at said position the nucleotide A is replaced by the nucleotide G; (b) a nucleic acid sequence encoding an IL-4 receptor (IL-4R), said IL-4R comprising at position 75 as shown in SEQ ID NO: 2 a valine; (c) a nucleic acid sequence comprising at least 15 nucleotides of the nucleic acid sequence of (a) or (b) and comprising the mutation as defined in (a) or (b); (d) a nucleic acid sequence comprising a nucleotide sequence as shown in SEQ ID NO: 3 or a fragment of the sequence as shown in SEQ ID NO: 3, said fragment comprising the nucleotide sequence "gtc"/"guc" as shown in position 5758 to 5760 of SEQ ID NO: 3 and said fragment comprising at least 15 nucleotides; (e) a nucleic acid sequence encoding a polypeptide comprising the amino acid sequence as shown in SEQ ID NO: 4; and (f) a nucleic acid sequence comprising at least 12 nucleotides which hybridizes under stringent conditions to a nucleotide sequence defined in any one of (a) to (e) and having a mutation as defined in (a) or (b). (a) a nucleic acid sequence encoding an IL-4 receptor (IL-4R) which contains a mutation in position 465 of the nucleotide sequence of the wild-type IL4R as shown in SEQ ID NO: 1, whereby at said position the nucleotide A is replaced by the nucleotide G; (b) a nucleic acid sequence encoding an IL-4 receptor (IL-4R), said IL-4R comprising at position 75 as shown in SEQ ID NO: 2 a valine; (c) a nucleic acid sequence comprising at least 15 nucleotides of the nucleic acid sequence of (a) or (b) and comprising the mutation as defined in (a) or (b); (d) a nucleic acid sequence comprising a nucleotide sequence as shown in SEQ ID NO: 3 or a fragment of the sequence as shown in SEQ ID NO: 3, said fragment comprising the nucleotide sequence "gtc"/"guc" as shown in position 5758 to 5760 of SEQ ID NO: 3 and said fragment comprising at least 15 nucleotides; (e) a nucleic acid sequence encoding a polypeptide comprising the amino acid sequence as shown in SEQ ID NO: 4; and (f) a nucleic acid sequence comprising at least 12 nucleotides which hybridizes under stringent conditions to a nucleotide sequence defined in any one of (a) to (e) and having a mutation as defined in (a) or (b).
A wiper blade coupled to a wiper arm of a vehicle to wipe a glass surface of a windshield, comprising: a heating element heating the wiper blade; a power source supplying power to the heating element; characterized in that it further comprises a vibration sensor detecting vibration of the vehicle, on which the wiper blade is mounted; and a controller operating the heating element based on the vibration detected by the vibration sensor. a heating element heating the wiper blade; a power source supplying power to the heating element; characterized in that it further comprises a vibration sensor detecting vibration of the vehicle, on which the wiper blade is mounted; and a controller operating the heating element based on the vibration detected by the vibration sensor.
A mobile terminal, comprising: a body (BD, 200) comprising a plurality of bodies (210, 220), positioned in a specific state between a first state in which the plurality of bodies are flat and a second state in which the plurality of bodies (210, 220) are folded; a flexible display positioned on one side of the body (BD, 200); a back cover positioned on the other side of the body (BD, 200), wherein when the position of the body is changed from the first state to the second state, at least a partial region of the body covered by the back cover is uncovered; a hinge assembly having a guide shaft coupled to the plurality of bodies (210, 220); and a bezel in an outer region of the flexible display wherein the guide shaft comprises a plurality of curved portions (CV1, CV2, CV3) in which at least one curvature is different from at least another curvature, wherein the bezel comprises: a first bezel on one side of the flexible display, and a second bezel at a position opposite to the first bezel about the flexible display, and a width of the first bezel is larger than that of the second bezel, and at least a partial region of the first bezel is a transparent or translucent region. a body (BD, 200) comprising a plurality of bodies (210, 220), positioned in a specific state between a first state in which the plurality of bodies are flat and a second state in which the plurality of bodies (210, 220) are folded; a flexible display positioned on one side of the body (BD, 200); a back cover positioned on the other side of the body (BD, 200), wherein when the position of the body is changed from the first state to the second state, at least a partial region of the body covered by the back cover is uncovered; a hinge assembly having a guide shaft coupled to the plurality of bodies (210, 220); and a bezel in an outer region of the flexible display wherein the guide shaft comprises a plurality of curved portions (CV1, CV2, CV3) in which at least one curvature is different from at least another curvature, wherein the bezel comprises: a first bezel on one side of the flexible display, and a second bezel at a position opposite to the first bezel about the flexible display, and a width of the first bezel is larger than that of the second bezel, and at least a partial region of the first bezel is a transparent or translucent region. a first bezel on one side of the flexible display, and a second bezel at a position opposite to the first bezel about the flexible display, and a width of the first bezel is larger than that of the second bezel, and at least a partial region of the first bezel is a transparent or translucent region.