mhurhangee/ep-ind-claims huggingface dataset:
A method for screening a molecule of interest comprising the following steps: a) putting into contact cells with a library of synthetic nanoparticles, each synthetic nanoparticle comprising a candidate molecule, a tracer and a single DNA tag specific to said candidate molecule, under conditions allowing said cells to integrate at least one of said synthetic nanoparticles, the candidate molecule being localised at the surface of of the synthetic nanoparticle, b) selecting the cells having integrated the tracer and having a phenotype of interest, c) identifying as a molecule of interest, the candidate molecule having been integrated into the cell selected in step b) by identifying the sequence of said single DNA tag. a) putting into contact cells with a library of synthetic nanoparticles, each synthetic nanoparticle comprising a candidate molecule, a tracer and a single DNA tag specific to said candidate molecule, under conditions allowing said cells to integrate at least one of said synthetic nanoparticles, the candidate molecule being localised at the surface of of the synthetic nanoparticle, b) selecting the cells having integrated the tracer and having a phenotype of interest, c) identifying as a molecule of interest, the candidate molecule having been integrated into the cell selected in step b) by identifying the sequence of said single DNA tag.
A method of extracting an analyte from a sample, the method comprising: adding the sample and a polymeric drying agent to a container, wherein the polymeric drying agent is a copolymer comprising a cationic monomer, an anionic monomer, and a crosslinker; and dispensing a solvent to the container; dissolving the analyte from the sample into the solvent; and sorbing water within the container by the polymeric drying agent, characterised in that: (i) the cationic monomer comprises [3-(methylacryloylamino) propyl]trimethylammonium chloride, the anionic monomer comprises 2-acrylamido-2-methyl-1-propanesulfonic acid, and the crosslinker comprises N,N'-methylenebis(acrylamide), or (ii) the cationic monomer comprises dimethylaminoethylacrylate, dimethylaminoethylmethacrylate, dimethylaminopropylacrylamide, dimethylaminopropylmethacrylamide, dimethylaminobenzylstyrene, diethylaminoethylstyrene, tertbutylaminoethylmethacrylate, or combinations thereof, the anionic monomer comprises acrylic acid, methacrylic acid, vinylbenzoic acid, 2-carboxyethyl acrylate, 2-acrylamidoglycolic acid, or combinations thereof, and the crosslinker comprises polyethylene glycol diacrylate. adding the sample and a polymeric drying agent to a container, wherein the polymeric drying agent is a copolymer comprising a cationic monomer, an anionic monomer, and a crosslinker; and dispensing a solvent to the container; dissolving the analyte from the sample into the solvent; and sorbing water within the container by the polymeric drying agent, characterised in that: (i) the cationic monomer comprises [3-(methylacryloylamino) propyl]trimethylammonium chloride, the anionic monomer comprises 2-acrylamido-2-methyl-1-propanesulfonic acid, and the crosslinker comprises N,N'-methylenebis(acrylamide), or (ii) the cationic monomer comprises dimethylaminoethylacrylate, dimethylaminoethylmethacrylate, dimethylaminopropylacrylamide, dimethylaminopropylmethacrylamide, dimethylaminobenzylstyrene, diethylaminoethylstyrene, tertbutylaminoethylmethacrylate, or combinations thereof, the anionic monomer comprises acrylic acid, methacrylic acid, vinylbenzoic acid, 2-carboxyethyl acrylate, 2-acrylamidoglycolic acid, or combinations thereof, and (i) the cationic monomer comprises [3-(methylacryloylamino) propyl]trimethylammonium chloride, the anionic monomer comprises 2-acrylamido-2-methyl-1-propanesulfonic acid, and the crosslinker comprises N,N'-methylenebis(acrylamide), or (ii) the cationic monomer comprises dimethylaminoethylacrylate, dimethylaminoethylmethacrylate, dimethylaminopropylacrylamide, dimethylaminopropylmethacrylamide, dimethylaminobenzylstyrene, diethylaminoethylstyrene, tertbutylaminoethylmethacrylate, or combinations thereof, the anionic monomer comprises acrylic acid, methacrylic acid, vinylbenzoic acid, 2-carboxyethyl acrylate, 2-acrylamidoglycolic acid, or combinations thereof, and the crosslinker comprises polyethylene glycol diacrylate.
An electrically driven surgical impacting tool and an adapter configured to interface a surgical implement with the surgical impacting tool, wherein: the surgical impacting tool includes an anvil and is configured to produce energy to move the anvil forward or rearward along an anvil axis; the adapter comprises: a surface for forward impacts to engage a forward impact surface of the surgical impacting tool; a surface for rearward impacts, distinct from the surface for forward impacts, to engage a rearward impact surface of the surgical impacting tool distinct from the forward impact surface of the surgical impacting tool; and a first lateral surface, a second lateral surface, and a third lateral surface, the first, second, and third surfaces (212a, 212b, 212c) forming distinct and respective first, second, and third planes that are each parallel to the anvil axis, wherein the first surface, the second surface, and the third surface allow for the adapter to be positioned with respect to the surgical impacting tool at distinct and respective first, second, and third rotational positions around the anvil axis; and the surface for forward impacts or the surface for rearward impacts is configured to contact the anvil during operation of the surgical impacting tool, and communicate an impact through the adapter to the surgical implement. the surgical impacting tool includes an anvil and is configured to produce energy to move the anvil forward or rearward along an anvil axis; the adapter comprises: a surface for forward impacts to engage a forward impact surface of the surgical impacting tool; a surface for rearward impacts, distinct from the surface for forward impacts, to engage a rearward impact surface of the surgical impacting tool distinct from the forward impact surface of the surgical impacting tool; and a first lateral surface, a second lateral surface, and a third lateral surface, the first, second, and third surfaces (212a, 212b, 212c) forming distinct and respective first, second, and third planes that are each parallel to the anvil axis, wherein a surface for forward impacts to engage a forward impact surface of the surgical impacting tool; a surface for rearward impacts, distinct from the surface for forward impacts, to engage a rearward impact surface of the surgical impacting tool distinct from the forward impact surface of the surgical impacting tool; and a first lateral surface, a second lateral surface, and a third lateral surface, the first, second, and third surfaces (212a, 212b, 212c) forming distinct and respective first, second, and third planes that are each parallel to the anvil axis, wherein the first surface, the second surface, and the third surface allow for the adapter to be positioned with respect to the surgical impacting tool at distinct and respective first, second, and third rotational positions around the anvil axis; and the surface for forward impacts or the surface for rearward impacts is configured to contact the anvil during operation of the surgical impacting tool, and communicate an impact through the adapter to the surgical implement.
A lubricating composition for use in an electric vehicle comprising: at least 95 weight percent of a lubricating base oil composition, the lubricating base oil composition including base oil selected from API Group III base oils or blends of Group III base oils with Group II, Group V base oils or mixtures thereof; at least a first dispersant being a phosphorylated succinimide dispersant containing 2 wt% to 3.5 wt% phosphorus, the phosphorylated succinimide dispersant providing 650 ppm or less phosphorus to the lubricating composition; the lubricating composition having 700 ppm or less total phosphorus and the phosphorylated succinimide dispersant provides at least 70% of the total phosphorus; and wherein the lubricating composition has a kinematic viscosity from 3 cSt to 6.5 cSt at 100°C; wherein if the lubricating base oil composition comprises API Group V base oil, the API Group V base oil is present in an amount up to 15 wt% based on the total lubricating composition; wherein if the lubricating base oil composition comprises API Group II base oil, the API Group II is present in an amount up to 80 wt% base on the total lubricating composition. at least 95 weight percent of a lubricating base oil composition, the lubricating base oil composition including base oil selected from API Group III base oils or blends of Group III base oils with Group II, Group V base oils or mixtures thereof; at least a first dispersant being a phosphorylated succinimide dispersant containing 2 wt% to 3.5 wt% phosphorus, the phosphorylated succinimide dispersant providing 650 ppm or less phosphorus to the lubricating composition; the lubricating composition having 700 ppm or less total phosphorus and the phosphorylated succinimide dispersant provides at least 70% of the total phosphorus; and wherein the lubricating composition has a kinematic viscosity from 3 cSt to 6.5 cSt at 100°C; wherein if the lubricating base oil composition comprises API Group V base oil, the API Group V base oil is present in an amount up to 15 wt% based on the total lubricating composition; wherein if the lubricating base oil composition comprises API Group II base oil, the API Group II is present in an amount up to 80 wt% base on the total lubricating composition.
Parking brake for a chassis of a rail vehicle, wherein the parking brake comprises at least one power generation unit, at least one power transmission unit, at least one friction element, at least one friction partner and at least one emergency release device with at least one first force transmission element, characterised in that an electrical actuator is connected at least with the first force transmission element of the at least one emergency release device and that the emergency release device has at least one second force transmission element which is connected to a handle.
Firearm comprising: - a fixed part for example grippable by a user; - at least one movable part that performs a predefined guided movement during the firing cycle having a cycle time, wherein the firing cycle comprises a retraction time in which the movable part is induced by the firing action to be disposed in a return position starting from a firing position, and an advancement time in which the movable part starting from a starting position is disposed in a firing position or wherein the movable part starting from a return position is disposed in a firing position; - an electronic system suitable to detect the shot fired event, comprising: i) a management unit; ii) a fixed sensor device integral with the fixed part of the firearm, preferably housed on the fixed part; iii) a mobile sensor device housed on board said movable part; wherein the fixed sensor device and the mobile sensor device are mutually magnetically sensitive so as to influence each other according to their mutual position, the mobile sensor device being an element made of a ferromagnetic material, preferably a permanent magnet, and the fixed sensor device comprising a magnetically sensitive element; wherein said movable part comprises a hammer and said mobile sensor device is housed on the hammer, or said movable part comprises a hammer and a return lever connected to the hammer and said mobile sensor device is housed on the return lever, or said movable part comprises a connection lever connecting the hammer to the trigger and said mobile sensor device is housed on the connection lever; wherein the management unit is operatively connected to the fixed sensor device and is suitable to detect a movement time (Tm) as a function of the position of the mobile sensor device during the retraction time; wherein the management unit is suitable to detect the shot-fired event upon the correspondence of movement time value (Tm) lower than a predefined threshold value (Ts), wherein the maximum value of the movement time value (Tm) is equal to the retraction time. - a fixed part for example grippable by a user; - at least one movable part that performs a predefined guided movement during the firing cycle having a cycle time, wherein the firing cycle comprises a retraction time in which the movable part is induced by the firing action to be disposed in a return position starting from a firing position, and an advancement time in which the movable part starting from a starting position is disposed in a firing position or wherein the movable part starting from a return position is disposed in a firing position; - an electronic system suitable to detect the shot fired event, comprising: i) a management unit; ii) a fixed sensor device integral with the fixed part of the firearm, preferably housed on the fixed part; iii) a mobile sensor device housed on board said movable part; i) a management unit; ii) a fixed sensor device integral with the fixed part of the firearm, preferably housed on the fixed part; iii) a mobile sensor device housed on board said movable part;
A method of reading a mark printed on containers moving along a conveyor, wherein the mark is printed on a lateral portion of the containers, the method comprising: supplying a container into a reading area; applying torque on the container at least in the reading area, generating rotation of said container along a vertical axis thereof; reading the mark of the container while the container is spinning, characterized in that the step of generating rotation of the container comprises applying torque by a spinner on a lateral wall of the container at a first zone of the reading area, and pushing the container against the spinner to ensure rotational movement of the container, wherein the step of pushing the container against the spinner comprises applying of a high-pressure air flow directed at least partially towards the first zone of the reading area. supplying a container into a reading area; applying torque on the container at least in the reading area, generating rotation of said container along a vertical axis thereof; reading the mark of the container while the container is spinning, characterized in that the step of generating rotation of the container comprises applying torque by a spinner on a lateral wall of the container at a first zone of the reading area, and pushing the container against the spinner to ensure rotational movement of the container, wherein the step of pushing the container against the spinner comprises applying of a high-pressure air flow directed at least partially towards the first zone of the reading area.
A paper cup comprising a sidewall member having an upper edge, a lower edge, a pair of opposite side edges (4,5), a front surface and a back surface, each of the side edges (4,5) and the upper edge defining upper corners, the side edges being overlapped and sealed together along an overlapping side seam, and a bottom member having a peripheral lip sealed to the lower edge of the sidewall member, characterized in that it further comprises at least one rigid or semi-rigid rim structure attached to the upper edge of the side wall member and in that the paper weight of the bottom member is greater than the paper weight of the sidewall member.
A washing machine having a basket within a drum for receiving articles to be laundered, and a chamber, wherein the washing machine is configured to provide a cycle having the following steps: (i) combining detergent in water in the chamber to provide a detergent solution wherein the detergent solution has a dilution factor of 40 or less and a surfactant concentration of at least 5,000 ppm, then (ii) spraying into the basket said detergent solution so as to dampen the articles in the basket, characterized in that the amount of detergent solution sprayed into the basket is from 50ml to 600ml per kilogram of articles to be laundered; and followed by (iii) a holding period of at least 5 minutes in which no water or further detergent solution is added to the basket containing the dampened articles. (i) combining detergent in water in the chamber to provide a detergent solution wherein the detergent solution has a dilution factor of 40 or less and a surfactant concentration of at least 5,000 ppm, then (ii) spraying into the basket said detergent solution so as to dampen the articles in the basket, characterized in that the amount of detergent solution sprayed into the basket is from 50ml to 600ml per kilogram of articles to be laundered; and followed by (iii) a holding period of at least 5 minutes in which no water or further detergent solution is added to the basket containing the dampened articles.
Lamp suitable for use in an automotive headlight of a motor vehicle, comprising - at least one filament arranged within a transparent lamp vessel, - the lamp vessel being bounded at one axial end by a top end and at another axial end by a lower end portion, - where said lamp vessel comprises a color filter portion through which light is emitted with a color change, and a color transparent portion, through which light is emitted without a color change, - where said color transparent portion is arranged such that an illumination beam of light is emitted from said filament through said color transparent portion to achieve a non-colored illumination, the illumination beam of light being a main portion of a luminous flux emitted from the lamp, being emitted into main illumination directions, and for use in a reflector of the automotive headlight to illuminate a road in front of the motor vehicle, wherein - said color transparent portion, at least for part of the circumference of the lamp vessel, extends between the top end and the lower end portion, and - said color filter portion is arranged such that a peripheral and/or a scattered portion of light (24, 26) from said filament is emitted through said color filter portion to achieve a color appearance outside of the angular range of the illumination beam of light. - at least one filament arranged within a transparent lamp vessel, - the lamp vessel being bounded at one axial end by a top end and at another axial end by a lower end portion, - where said lamp vessel comprises a color filter portion through which light is emitted with a color change, and a color transparent portion, through which light is emitted without a color change, - where said color transparent portion is arranged such that an illumination beam of light is emitted from said filament through said color transparent portion to achieve a non-colored illumination, the illumination beam of light being a main portion of a luminous flux emitted from the lamp, being emitted into main illumination directions, and for use in a reflector of the automotive headlight to illuminate a road in front of the motor vehicle, wherein - said color transparent portion, at least for part of the circumference of the lamp vessel, extends between the top end and the lower end portion, and - said color filter portion is arranged such that a peripheral and/or a scattered portion of light (24, 26) from said filament is emitted through said color filter portion to achieve a color appearance outside of the angular range of the illumination beam of light.
A laminate for a light emitting device, comprising: a glass substrate comprising potassium or a glass substrate coated with a mineral layer comprising potassium; and an internal light extraction layer formed from a glass frit having a refractive index of 1.8 to 2.1 on said glass substrate or on said mineral layer, wherein the internal light extraction layer comprises an interface void layer at an interface with the glass substrate or the mineral layer, characterised in that the interface void layer has a thickness of 1 to 5 μm, the interface void layer has a void area ratio of 40 to 90%, and a surface of the glass substrate or the mineral layer comprises potassium at a concentration of 1 to 15% by weight. a glass substrate comprising potassium or a glass substrate coated with a mineral layer comprising potassium; and an internal light extraction layer formed from a glass frit having a refractive index of 1.8 to 2.1 on said glass substrate or on said mineral layer, wherein the internal light extraction layer comprises an interface void layer at an interface with the glass substrate or the mineral layer, characterised in that the interface void layer has a thickness of 1 to 5 μm, the interface void layer has a void area ratio of 40 to 90%, and a surface of the glass substrate or the mineral layer comprises potassium at a concentration of 1 to 15% by weight.
A method of synthesizing 6-(5-methoxyhept-1-yl)bicyclo [3.3.0] octan-3-one, the method comprising: i) reacting a first mixture comprising 7,7-dichloro-4-(5-methoxyhept-1-yl)bicyclo[3.2.0]heptan-6-one and 6,6-dichloro-4-(5-methoxyhept-1-yl)bicyclo[3.2.0]heptan-7-one with acetic acid and zinc to form a second mixture comprising 4-(5-methoxyhept-1-yl)bicyclo[3.2.0]heptan-6-one and 4-(5-methoxyhept-1-yl)bicyclo [3.2.0]heptan-7-one; ii) reacting the second mixture with trimethylsulfonium iodide to form a third mixture comprising 2-(5-methoxyhept-1-yl)spiro[bicyclo[3.2.0]heptane-6,2'-oxirane] and 4-(5-methoxyhept-1-yl)-spiro[bicyclo[3.2.0]heptane-6,2'-oxirane]; and iii) reacting the third mixture with a Lewis acid to form 6-(5-methoxyhept-1-yl)bicyclo [3.3.0] octan-3-one. i) reacting a first mixture comprising 7,7-dichloro-4-(5-methoxyhept-1-yl)bicyclo[3.2.0]heptan-6-one and 6,6-dichloro-4-(5-methoxyhept-1-yl)bicyclo[3.2.0]heptan-7-one with acetic acid and zinc to form a second mixture comprising 4-(5-methoxyhept-1-yl)bicyclo[3.2.0]heptan-6-one and 4-(5-methoxyhept-1-yl)bicyclo [3.2.0]heptan-7-one; 7,7-dichloro-4-(5-methoxyhept-1-yl)bicyclo[3.2.0]heptan-6-one and 6,6-dichloro-4-(5-methoxyhept-1-yl)bicyclo[3.2.0]heptan-7-one with acetic acid and zinc to form a second mixture comprising 4-(5-methoxyhept-1-yl)bicyclo[3.2.0]heptan-6-one and 4-(5-methoxyhept-1-yl)bicyclo [3.2.0]heptan-7-one; ii) reacting the second mixture with trimethylsulfonium iodide to form a third mixture comprising 2-(5-methoxyhept-1-yl)spiro[bicyclo[3.2.0]heptane-6,2'-oxirane] and 4-(5-methoxyhept-1-yl)-spiro[bicyclo[3.2.0]heptane-6,2'-oxirane]; and 2-(5-methoxyhept-1-yl)spiro[bicyclo[3.2.0]heptane-6,2'-oxirane] and 4-(5-methoxyhept-1-yl)-spiro[bicyclo[3.2.0]heptane-6,2'-oxirane]; and iii) reacting the third mixture with a Lewis acid to form 6-(5-methoxyhept-1-yl)bicyclo [3.3.0] octan-3-one.