A method for the enzymatic synthesis of an enantiomerically enriched -amine of general formula [c] from the corresponding ketone of the general formula [a] and a suitable amino donor, wherein R 1 and R 2 are different and are independently linear or branched aliphatic, aromatic, hetero-aromatic or form a cyclic structure, by using a transaminase selected from the group consisting of a. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 1; b. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 3; c. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 5; d. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 7; e. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 9; f. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 11; g. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 13; h. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 15; i. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 17; j. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 19; k. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 21; l. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 23; m. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 25 and n. a protein having transaminase activity and obtainable from an organism selected from the group of organisms consisting of Rahnella aquatilis, Ochrobactrum anthropi, Ochrobactrum tritici, Sinorhizobium morelense, Curtobacterium pusilllum, Paecilomyces lilacinus, Microbacterium ginsengisoli, Microbacterium trichothecenolyticum, Pseudomonas citronellolis, Yersinia kristensenii, Achromobacter spanius, Achromobacter insolitus, Mycobacterium fortuitum, Mycobacterium frederiksbergense, Mycobacterium sacrum, Mycobacterium fluoranthenivorans, Burkholderia sp., Burkholderia tropica, Cosmospora episphaeria, and Fusarium oxysporum with the proviso that the above-mentioned proteins (i.e. alternative (a)) do not consist of an amino acid sequence identical to the amino acid sequences SEQ ID no. 3 of WO2011/026556 a. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 1; b. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 3; c. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 5; d. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 7; e. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 9; f. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 11; g. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 13; h. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 15; i. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 17; j. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 19; k. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 21; l. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 23; m. a protein having at least 90 % identity to the amino acid sequence of SEQ ID No. 25 and n. a protein having transaminase activity and obtainable from an organism selected from the group of organisms consisting of Rahnella aquatilis, Ochrobactrum anthropi, Ochrobactrum tritici, Sinorhizobium morelense, Curtobacterium pusilllum, Paecilomyces lilacinus, Microbacterium ginsengisoli, Microbacterium trichothecenolyticum, Pseudomonas citronellolis, Yersinia kristensenii, Achromobacter spanius, Achromobacter insolitus, Mycobacterium fortuitum, Mycobacterium frederiksbergense, Mycobacterium sacrum, Mycobacterium fluoranthenivorans, Burkholderia sp., Burkholderia tropica, Cosmospora episphaeria, and Fusarium oxysporum with the proviso that the above-mentioned proteins (i.e. alternative (a)) do not consist of an amino acid sequence identical to the amino acid sequences SEQ ID no. 3 of WO2011/026556