mhurhangee/ep-ind-claims huggingface dataset:
A process for preparing a substantially pure β-D- or β-L-1,3-dioxolane nucleoside comprising: a) obtaining an esterified 2,2-dialkoxy ethanol of the formula (Ia) or the compound of formula (Ib); wherein: each R 1 is independently alkyl, aryl, heteroaryl, heterocyclic, alkaryl, alkylheteroaryl, or alkylheterocyclic, or aralkyl; and R 2 is any suitable removable group; b) cyclizing the esterified 2,2-dialkoxy ethanol of the formula (Ia) or the compound of formula (Ib) with glycolic acid to obtain a 1,3-dioxolane lactone of the formula: c) resolving the 1,3-dioxolane lactone of the formula to obtain a substantially pure D- or L-lactone; d) selectively reducing with a reducing agent and activating the substantially pure D- or L-chiral lactone to obtain a substantially pure D- or L-1,3-dioxolane of the formula: wherein L is a suitable leaving group; e) coupling the substantially pure D- or L-1,3-dioxolane of the formula to an activated and/or protected purine or pyrimidine base or its derivative to obtain α:β mixture of substantially pure protected D- or L-1,3-dioxolane nucleosides of the formula: wherein B is a purine or pyrimidine base or its derivative; f) optionally purifying the α:β mixture of substantially pure protected D- or L-1,3-dioxolane nucleosides of the formula to obtain a substantially pure protected β-D- or β-L-1,3-dioxolane nucleoside; and g) optionally deprotecting the substantially pure protected P-D- or P-L-1,3-dioxolane nucleoside to obtain a substantially pure β-D- or β-L-1,3-dioxolane nucleoside. a) obtaining an esterified 2,2-dialkoxy ethanol of the formula (Ia) or the compound of formula (Ib); wherein: each R 1 is independently alkyl, aryl, heteroaryl, heterocyclic, alkaryl, alkylheteroaryl, or alkylheterocyclic, or aralkyl; and R 2 is any suitable removable group; each R 1 is independently alkyl, aryl, heteroaryl, heterocyclic, alkaryl, alkylheteroaryl, or alkylheterocyclic, or aralkyl; and R 2 is any suitable removable group; b) cyclizing the esterified 2,2-dialkoxy ethanol of the formula (Ia) or the compound of formula (Ib) with glycolic acid to obtain a 1,3-dioxolane lactone of the formula: c) resolving the 1,3-dioxolane lactone of the formula to obtain a substantially pure D- or L-lactone; d) selectively reducing with a reducing agent and activating the substantially pure D- or L-chiral lactone to obtain a substantially pure D- or L-1,3-dioxolane of the formula: wherein L is a suitable leaving group; e) coupling the substantially pure D- or L-1,3-dioxolane of the formula to an activated and/or protected purine or pyrimidine base or its derivative to obtain α:β mixture of substantially pure protected D- or L-1,3-dioxolane nucleosides of the formula: wherein B is a purine or pyrimidine base or its derivative; f) optionally purifying the α:β mixture of substantially pure protected D- or L-1,3-dioxolane nucleosides of the formula to obtain a substantially pure protected β-D- or β-L-1,3-dioxolane nucleoside; and g) optionally deprotecting the substantially pure protected P-D- or P-L-1,3-dioxolane nucleoside to obtain a substantially pure β-D- or β-L-1,3-dioxolane nucleoside.
A fuel cell seal assembly (56; 256), comprising: a seal that is configured to restrict flow of a fuel cell fluid through at least one of an outer lateral edge (60; 160; 260; 360) of a first gas diffusion layer (18; 118; 218; 318), an outer lateral edge (64; 164; 264; 364) of a membrane electrode assembly (50; 150; 250; 350), an outer lateral edge (68; 168; 268; 368) of a second gas diffusion layer (22; 122; 222; 322), wherein the outer lateral edge (60; 160; 260; 360) of the first gas diffusion layer (18; 118; 218; 318) is laterally spaced from the outer lateral edge (68; 168; 268; 368) of the second gas diffusion layer (22; 122; 222; 322), wherein the seal is secured about the periphery of the first gas diffusion layer (18; 118; 218; 318), the membrane electrode assembly (50; 150; 250; 350), and the second gas diffusion layer (22; 122; 222; 322), wherein the outer lateral edge (60; 160; 260; 360) of the first gas diffusion layer (18; 118; 218; 318) extends laterally past the outer lateral edge (68; 168; 268; 368) of the second gas diffusion layer (22; 122; 222; 322) on a first outboard side (X 1) of the fuel cell seal assembly (56; 256), characterized in that the outer lateral edge (68; 168; 268; 368) of the second gas diffusion layer (22; 122; 222; 322) extends laterally past the outer lateral edge (60; 160; 260; 360) of the first gas diffusion layer (18; 118; 218; 318) on a second outboard side (X 2) that is transverse to the first outboard side (X 1). a seal that is configured to restrict flow of a fuel cell fluid through at least one of an outer lateral edge (60; 160; 260; 360) of a first gas diffusion layer (18; 118; 218; 318), an outer lateral edge (64; 164; 264; 364) of a membrane electrode assembly (50; 150; 250; 350), an outer lateral edge (68; 168; 268; 368) of a second gas diffusion layer (22; 122; 222; 322), wherein the outer lateral edge (60; 160; 260; 360) of the first gas diffusion layer (18; 118; 218; 318) is laterally spaced from the outer lateral edge (68; 168; 268; 368) of the second gas diffusion layer (22; 122; 222; 322), wherein the seal is secured about the periphery of the first gas diffusion layer (18; 118; 218; 318), the membrane electrode assembly (50; 150; 250; 350), and the second gas diffusion layer (22; 122; 222; 322), wherein the outer lateral edge (60; 160; 260; 360) of the first gas diffusion layer (18; 118; 218; 318) extends laterally past the outer lateral edge (68; 168; 268; 368) of the second gas diffusion layer (22; 122; 222; 322) on a first outboard side (X 1) of the fuel cell seal assembly (56; 256), characterized in that the outer lateral edge (68; 168; 268; 368) of the second gas diffusion layer (22; 122; 222; 322) extends laterally past the outer lateral edge (60; 160; 260; 360) of the first gas diffusion layer (18; 118; 218; 318) on a second outboard side (X 2) that is transverse to the first outboard side (X 1).
A device for inserting a bouquet into a vase, containing - an upper carrier surface, - a support wall adjoining the underside of the carrier surface and - several small tubes, which are inserted into the carrier surface and which are open on one side on the lower end thereof, characterized in that - the small tubes are closed on the upper end thereof and - have at least one lateral opening in the region of the upper end thereof, and that - the small tube are thin-walled and have an outer diameter of 130 um to 200 um and - an inner diameter of 120 um to 190 μm. - an upper carrier surface, - a support wall adjoining the underside of the carrier surface and - several small tubes, which are inserted into the carrier surface and which are open on one side on the lower end thereof, - the small tubes are closed on the upper end thereof and - have at least one lateral opening in the region of the upper end thereof, and that - the small tube are thin-walled and have an outer diameter of 130 um to 200 um and - an inner diameter of 120 um to 190 μm.
A radiation-sensitive composition comprising: a polymer comprising a first structural unit that comprises an acid-labile group; a first compound that generates a first acid upon an irradiation with a radioactive ray; and a second compound that generates a second acid upon an irradiation with a radioactive ray, wherein, the first acid does not substantially dissociate the acid-labile group under a condition of a temperature of 110 °C and a time period of 1 min, and the second acid dissociates the acid-labile group under a condition of a temperature of 110 °C and a time period of 1 min, and the radiation-sensitive composition satisfies at least one of requirements and: the polymer comprises a monovalent iodine atom; and the radiation-sensitive composition further comprises a third compound that is other than the first compound or the second compound, and that comprises a monovalent iodine atom. a polymer comprising a first structural unit that comprises an acid-labile group; a first compound that generates a first acid upon an irradiation with a radioactive ray; and a second compound that generates a second acid upon an irradiation with a radioactive ray, wherein, the first acid does not substantially dissociate the acid-labile group under a condition of a temperature of 110 °C and a time period of 1 min, and the second acid dissociates the acid-labile group under a condition of a temperature of 110 °C and a time period of 1 min, and the radiation-sensitive composition satisfies at least one of requirements and: the polymer comprises a monovalent iodine atom; and the radiation-sensitive composition further comprises a third compound that is other than the first compound or the second compound, and that comprises a monovalent iodine atom. the polymer comprises a monovalent iodine atom; and the radiation-sensitive composition further comprises a third compound that is other than the first compound or the second compound, and that comprises a monovalent iodine atom.
A paper recycling device comprising: a dry type defibrator for crushing paper and defibrating it, a first transport unit for conveying defibrated material defibrated by the dry type defibrator, a classifier unit that is arranged to do deinking of the defibrated material transported by the first transport unit, a second transport unit that is arranged to transport the defibrated material deinked by the classifier unit, and a paper forming unit that is arranged to form paper with the defibrated material transported by the second transport unit, wherein the classifier unit is arranged to do deinking by doing air flow classification of the defibrated material transported by the first transport unit, characterized in that the first transport unit comprises a first transport pipe provided with an adjustment unit for performing adjustment of the transport cross section of the first transport pipe and thereby performing adjustment of the air flow that transports fibers in the first transport pipe, so that the flow velocity of the air flow of the classifier unit's connecting part with the first transport unit is larger than the flow velocity of the air flow of the dry type defibrator unit's connecting part with the first transport unit. a dry type defibrator for crushing paper and defibrating it, a first transport unit for conveying defibrated material defibrated by the dry type defibrator, a classifier unit that is arranged to do deinking of the defibrated material transported by the first transport unit, a second transport unit that is arranged to transport the defibrated material deinked by the classifier unit, and a paper forming unit that is arranged to form paper with the defibrated material transported by the second transport unit, wherein the classifier unit is arranged to do deinking by doing air flow classification of the defibrated material transported by the first transport unit, characterized in that the first transport unit comprises a first transport pipe provided with an adjustment unit for performing adjustment of the transport cross section of the first transport pipe and thereby performing adjustment of the air flow that transports fibers in the first transport pipe, so that the flow velocity of the air flow of the classifier unit's connecting part with the first transport unit is larger than the flow velocity of the air flow of the dry type defibrator unit's connecting part with the first transport unit.
A process for gelatinisation and the enzymatic hydrolysis of flour which comprises passing said flour through a twin-screw extruder in the presence of 0.025 % to 1.5 % w/w relative to flour of an α-amylase hydrolytic enzyme and in the presence of water at a moisture level from 30% to 45% w/w relative to the total quantity of ingredients, at a screw speed from 300 RPM to 800 RPM and a temperature in the range from 80°C to 160°C; the dimensions of the extruder being such that the residence time of the flour through the extruder is from 60 to 120 seconds and results in a dextrinised product having a dextrose equivalent of at least 15.
A process for starch cationization, comprising the steps of: providing a powdered starch, having a moisture content not higher than 5% by weight of the total weight of the starch, reacting said starch with boron trifluoride (BF 3) at a temperature comprised between 5°C and 100°C, with a weight ratio between boron trifluoride and starch of 0.01 to 1.0. providing a powdered starch, having a moisture content not higher than 5% by weight of the total weight of the starch, reacting said starch with boron trifluoride (BF 3) at a temperature comprised between 5°C and 100°C, with a weight ratio between boron trifluoride and starch of 0.01 to 1.0.
Facade system with a supporting structure which, at the rear, can be attached to the wall of a building, where the supporting structure has upright posts and horizontally arranged bars, and with facade panels which are fixed to the front of the supporting structure, where the supporting structure has retaining ducts which run parallel to the wall of the building and open onto the front side of the supporting structure, the cross-section of which ducts is wider than the opening, scaffold anchors are assigned to the retaining ducts which have a retaining section extending into a retaining duct and a connecting section extending in front of the supporting structure, and the connecting section has connecting means permitting the connection of a scaffold, characterised in that the retaining section is divided into two parts in such a way that each of the two parts can be inserted into the opening of a retaining duct from the front of the supporting structure independently of the other part, and both parts, when arranged to rest on one another, form a substantially T-shaped retaining head, by means of which the scaffold anchor is held securely in the retaining duct against forward-acting forces.
A method of initiating handover between cells of a High-Speed Downlink Packet Access wireless telecommunications network where user equipment receives a data stream on a common frequency from both a serving cell and at least one assisting serving cell, said method comprising: in response to a received message from a controlling network node identifying that a change in serving cell is required, transmitting a level 1 message from a target serving base station supporting a target serving cell to said user equipment instructing said user equipment to handover to said target serving cell and indicating to said user equipment whether to continue to utilise each of said at least one assisting serving cell, characterised by said message indicating to said user equipment a revised subframe pairing between said target serving cell and each of some of said at least one assisting serving cell. in response to a received message from a controlling network node identifying that a change in serving cell is required, transmitting a level 1 message from a target serving base station supporting a target serving cell to said user equipment instructing said user equipment to handover to said target serving cell and indicating to said user equipment whether to continue to utilise each of said at least one assisting serving cell, characterised by said message indicating to said user equipment a revised subframe pairing between said target serving cell and each of some of said at least one assisting serving cell.
A control module for controlling a field-effect transistor having a gate, a drain and a source, the control module comprising: a comparator operable to receive the drain-to-source voltage (V ds) of the transistor and compare it to a threshold voltage, the comparator comprising a clock input operable to receive a gate voltage of the transistor, wherein the comparator is further operable to latch a result of the comparison to an output of the comparator on the basis of the received gate voltage; and control circuitry operable to receive the comparator output and to perform a control function with respect to the transistor based on the value of the comparator output; wherein the comparator further comprises: a first output configured to provide an on-late flag indicative of whether the gate voltage turned the transistor on before or after the drain-to-source voltage (V ds) went from high to low, wherein the comparator is further operable to latch a result of the comparison to the first output of the comparator on the basis of a rising edge of the received gate voltage; and a second output configured to provide an off-late flag indicative of whether the gate voltage turned the transistor off before or after the drain-to-source voltage (V ds) went from low to high, wherein the comparator is further operable to latch a result of the comparison to the second output of the comparator on the basis of a falling edge of the received gate voltage. a comparator operable to receive the drain-to-source voltage (V ds) of the transistor and compare it to a threshold voltage, the comparator comprising a clock input operable to receive a gate voltage of the transistor, wherein the comparator is further operable to latch a result of the comparison to an output of the comparator on the basis of the received gate voltage; and control circuitry operable to receive the comparator output and to perform a control function with respect to the transistor based on the value of the comparator output; a first output configured to provide an on-late flag indicative of whether the gate voltage turned the transistor on before or after the drain-to-source voltage (V ds) went from high to low, wherein the comparator is further operable to latch a result of the comparison to the first output of the comparator on the basis of a rising edge of the received gate voltage; and a second output configured to provide an off-late flag indicative of whether the gate voltage turned the transistor off before or after the drain-to-source voltage (V ds) went from low to high, wherein the comparator is further operable to latch a result of the comparison to the second output of the comparator on the basis of a falling edge of the received gate voltage.
A method of purifying a protein of interest from a mixture comprising the protein of interest and one or more contaminants, comprising: (a) determining the pI of the most acidic isoform of the protein of interest in the mixture, wherein the mixture is produced from culturing a host cell that expresses the protein of interest; (b) contacting the protein of interest with a cation exchange resin at a first pH that is less than the pI of the most acidic isoform of the protein of interest, such that the protein of interest binds to the resin; (c) washing the cation exchange resin at a second pH that is greater than the first pH, but less than the pI of the most acidic isoform of the protein of interest; and (d) eluting the protein of interest from the resin at a third pH that is equal to or less than the first pH, thereby purifying the protein of interest. (a) determining the pI of the most acidic isoform of the protein of interest in the mixture, wherein the mixture is produced from culturing a host cell that expresses the protein of interest; (b) contacting the protein of interest with a cation exchange resin at a first pH that is less than the pI of the most acidic isoform of the protein of interest, such that the protein of interest binds to the resin; (c) washing the cation exchange resin at a second pH that is greater than the first pH, but less than the pI of the most acidic isoform of the protein of interest; and (d) eluting the protein of interest from the resin at a third pH that is equal to or less than the first pH, thereby purifying the protein of interest.
A steer-by-wire system, comprising a first control device, which controls at least one steering actuator, and at least one second control device, which controls at least one actuator on a steering handle, in order to generate a haptic torque, wherein a sensor system for detecting a steering wheel angle is associated with the second control device, wherein the first control device is connected to a first bus system and the second control device is connected to a second bus system, characterized in that the two bus systems (9, 10) are connected to one another via a gateway control device and the first control device and the second control device are directly connected with one another via a third bus system.
A method of manufacturing a security sheet comprising: forming a plurality of perforations through at least one core layer comprising plastic, from a first core surface to a second core surface of said at least one core layer; after forming the plurality of perforations, feeding a security element through the plurality of perforations such that the security element extends through the at least one core layer from the first core surface to the second core surface; locating at least one first region of the security element over part of the first core surface and locating at least one second region of the security element over part of the second core surface; and laminating together the at least one core layer and the security element. forming a plurality of perforations through at least one core layer comprising plastic, from a first core surface to a second core surface of said at least one core layer; after forming the plurality of perforations, feeding a security element through the plurality of perforations such that the security element extends through the at least one core layer from the first core surface to the second core surface; locating at least one first region of the security element over part of the first core surface and locating at least one second region of the security element over part of the second core surface; and laminating together the at least one core layer and the security element.
A mixer base assembly comprising: (a) a body having: (i) an upper end including a mating face for mixing vessel connection; (ii) a lower end including a cavity; (iii) a plurality of side walls (551A, 551B, 551C, 551D); (iv) an inlet port arranged in a side wall; (v) an outlet port arranged in a side wall; and, (vi) a fluid mixing chamber having a bottom wall; (b) an impeller seat arranged in the cavity in the lower end of the body; and, (c) a levitating magnetic impeller arranged in the impeller seat, the impeller comprising a magnet, a base, and at least two blades (651A, 651B, 651C, 651D), wherein the at least two blades (651A, 651B, 651C, 651D) extend above the bottom wall of the fluid mixing chamber into the fluid mixing chamber, characterized in that the body has: (vii) a sampling port arranged in a side wall; and (viii) at least one probe port (518; 519) arranged in a side wall. (a) a body having: (i) an upper end including a mating face for mixing vessel connection; (ii) a lower end including a cavity; (iii) a plurality of side walls (551A, 551B, 551C, 551D); (iv) an inlet port arranged in a side wall; (v) an outlet port arranged in a side wall; and, (vi) a fluid mixing chamber having a bottom wall; (i) an upper end including a mating face for mixing vessel connection; (ii) a lower end including a cavity; (iii) a plurality of side walls (551A, 551B, 551C, 551D); (iv) an inlet port arranged in a side wall; (v) an outlet port arranged in a side wall; and, (vi) a fluid mixing chamber having a bottom wall; (b) an impeller seat arranged in the cavity in the lower end of the body; and, (c) a levitating magnetic impeller arranged in the impeller seat, the impeller comprising a magnet, a base, and at least two blades (651A, 651B, 651C, 651D), wherein the at least two blades (651A, 651B, 651C, 651D) extend above the bottom wall of the fluid mixing chamber into the fluid mixing chamber, (vii) a sampling port arranged in a side wall; and (viii) at least one probe port (518; 519) arranged in a side wall.