mhurhangee/ep-ind-claims huggingface dataset:
A DNA molecule comprising: a modified Group II intron which does not express the intron-encoded reverse transcriptase but which contains a modified selectable marker gene in the reverse orientation relative to the modified Group II intron, wherein the selectable marker gene comprises a region encoding a selectable marker and a promoter operably linked to said region, which promoter is capable of causing expression of the selectable marker encoded by a single copy of the selectable marker gene in an amount sufficient for the selectable marker to alter the phenotype of a bacterial cell of the class Clostridia such that it can be distinguished from the bacterial cell of the class Clostridia lacking the selectable marker gene; and a promoter for transcription of the modified Group II intron, said promoter being operably linked to said modified Group II intron; wherein the modified selectable marker gene contains a Group I intron positioned in the forward orientation relative to the modified Group II intron so as to disrupt expression of the selectable marker; wherein the DNA molecule allows for removal of the Group I intron from the RNA transcript of the modified Group II intron to leave a region encoding the selectable marker and allows for the insertion of said RNA transcript or a DNA copy thereof at a site in a DNA molecule in a bacterial cell of the class Clostridia; and wherein the selectable marker confers erythromycin resistance to the bacterial cell of the class Clostridia. a modified Group II intron which does not express the intron-encoded reverse transcriptase but which contains a modified selectable marker gene in the reverse orientation relative to the modified Group II intron, wherein the selectable marker gene comprises a region encoding a selectable marker and a promoter operably linked to said region, which promoter is capable of causing expression of the selectable marker encoded by a single copy of the selectable marker gene in an amount sufficient for the selectable marker to alter the phenotype of a bacterial cell of the class Clostridia such that it can be distinguished from the bacterial cell of the class Clostridia lacking the selectable marker gene; and a promoter for transcription of the modified Group II intron, said promoter being operably linked to said modified Group II intron; wherein the modified selectable marker gene contains a Group I intron positioned in the forward orientation relative to the modified Group II intron so as to disrupt expression of the selectable marker; wherein the DNA molecule allows for removal of the Group I intron from the RNA transcript of the modified Group II intron to leave a region encoding the selectable marker and allows for the insertion of said RNA transcript or a DNA copy thereof at a site in a DNA molecule in a bacterial cell of the class Clostridia; and wherein the selectable marker confers erythromycin resistance to the bacterial cell of the class Clostridia.
A drop nozzle for an agricultural sprayer, comprising: a valve assembly including a shutoff valve; a tube operably connected to the valve assembly; and an airfoil connected to the tube, the air foil comprising a fin; and a shield connected to a bottom surface of the fin. a valve assembly including a shutoff valve; a tube operably connected to the valve assembly; and an airfoil connected to the tube, the air foil comprising a fin; and a shield connected to a bottom surface of the fin.
A vehicle headlamp comprising: a light source; and a reflection surface adapted to reflect light from the light source and emit the reflected light forward of a vehicle in a predetermined light distribution pattern, wherein the light source is disposed at or near a reference focal point of the reflection surface, wherein the reflection surface is divided into reflection surfaces on upper and lower sides in a direction in which the light from the light source is to be radiated, with respect to a normal line passing through a center of the light source or proximity thereof is characterized in that the light source is a semiconductor-type light source and that either one of the reflection surfaces on the upper and lower sides is a convergent scattering reflection surface (31U-34U), and the other one is a divergent scattering reflection surface (31D-34D). a light source; and a reflection surface adapted to reflect light from the light source and emit the reflected light forward of a vehicle in a predetermined light distribution pattern, wherein the light source is disposed at or near a reference focal point of the reflection surface, wherein the reflection surface is divided into reflection surfaces on upper and lower sides in a direction in which the light from the light source is to be radiated, with respect to a normal line passing through a center of the light source or proximity thereof is characterized in that the light source is a semiconductor-type light source and that either one of the reflection surfaces on the upper and lower sides is a convergent scattering reflection surface (31U-34U), and the other one is a divergent scattering reflection surface (31D-34D).
A motor control device (10; 90) including a motor current detector detecting current in windings to control an operation of a motor with a stator having the windings of three phases, the motor control device (10; 90) comprising: a digital controller (17; 97) outputting a PWM switching signal based on an operation command from a host device, positional information from an encoder, and a detected motor current value that is a value of current in the windings; a power converter (18; 98) applying drive voltage to the windings by turning on and off a switching element according to the PWM switching signal; the motor current detector converting current flowing in the windings by the drive voltage to analog voltage; a ΔΣ AD converter converting the analog voltage to a 1-bit digital signal; an AD conversion decimating filter converting the 1-bit digital signal to a multi-bit digital signal, and outputting the multi-bit digital signal as the detected motor current value; a clock generator generating a clock for operating the ΔΣ AD converter and the AD conversion decimating filter, characterized in that the motor control device (10; 90) further comprises a stop signal generator (19; 59; 69) generating a clock stop signal that stops the clock of the clock generator for a predetermined period being longer than duration of leak current which occurs at the moment of turning on and off the switching element, wherein the stop signal generator (19; 59; 69) generates the clock stop signal with a predetermined pulse width based on a timing of change of the PWM switching signal, and the clock generator uses the clock stop signal to stop the clock for a period of the predetermined pulse width. a digital controller (17; 97) outputting a PWM switching signal based on an operation command from a host device, positional information from an encoder, and a detected motor current value that is a value of current in the windings; a power converter (18; 98) applying drive voltage to the windings by turning on and off a switching element according to the PWM switching signal; the motor current detector converting current flowing in the windings by the drive voltage to analog voltage; a ΔΣ AD converter converting the analog voltage to a 1-bit digital signal; an AD conversion decimating filter converting the 1-bit digital signal to a multi-bit digital signal, and outputting the multi-bit digital signal as the detected motor current value; a clock generator generating a clock for operating the ΔΣ AD converter and the AD conversion decimating filter, characterized in that the motor control device (10; 90) further comprises a stop signal generator (19; 59; 69) generating a clock stop signal that stops the clock of the clock generator for a predetermined period being longer than duration of leak current which occurs at the moment of turning on and off the switching element, wherein the stop signal generator (19; 59; 69) generates the clock stop signal with a predetermined pulse width based on a timing of change of the PWM switching signal, and the clock generator uses the clock stop signal to stop the clock for a period of the predetermined pulse width.
A method, performed in a multipath Transmission Control Protocol, MPTCP, proxy configured with an Internet Protocol, IP, address and an additional IP address, of relaying data between an MPTCP capable wireless device and a server, the method comprising: - establishing a multipath Transmission Control Protocol, MPTCP, session between the MPTCP proxy and the wireless device, the MPTCP session comprising a first MPTCP subflow mapped on a first network path for the wireless device using a default traffic flow tuple, wherein for setting up the first MPTCP subflow a Traffic Flow Template, TFT, with the IP address configured for the MPTCP proxy and an IP address configured for the wireless device is used; - establishing a TCP session with the server; - after establishing the TCP session with the server, initiating a further MPTCP subflow in the MPTCP session between the MPTCP proxy and the wireless device based on a mapping of the further MPTCP subflow to a second network path for the wireless device using a filtering traffic flow tuple comprising the additional IP address configured for the MPTCP proxy, wherein for setting up the further MPTCP subflow a TFT with the additional IP address configured for the MPTCP proxy and the IP address configured for the wireless device is used; and - relaying data between the wireless device and the server, wherein data between the MPTCP proxy and the wireless device is exchanged in the MPTCP session comprising the first MPTCP subflow on the first network path and the further MPTCP subflow on the second network path and wherein data between the MPTCP proxy and the server is exchanged in the TCP session. - establishing a multipath Transmission Control Protocol, MPTCP, session between the MPTCP proxy and the wireless device, the MPTCP session comprising a first MPTCP subflow mapped on a first network path for the wireless device using a default traffic flow tuple, wherein for setting up the first MPTCP subflow a Traffic Flow Template, TFT, with the IP address configured for the MPTCP proxy and an IP address configured for the wireless device is used; - establishing a TCP session with the server; - after establishing the TCP session with the server, initiating a further MPTCP subflow in the MPTCP session between the MPTCP proxy and the wireless device based on a mapping of the further MPTCP subflow to a second network path for the wireless device using a filtering traffic flow tuple comprising the additional IP address configured for the MPTCP proxy, wherein for setting up the further MPTCP subflow a TFT with the additional IP address configured for the MPTCP proxy and the IP address configured for the wireless device is used; and - relaying data between the wireless device and the server, wherein data between the MPTCP proxy and the wireless device is exchanged in the MPTCP session comprising the first MPTCP subflow on the first network path and the further MPTCP subflow on the second network path and wherein data between the MPTCP proxy and the server is exchanged in the TCP session.
A method of selectively sintering particulate material, the method comprising: providing a layer of particulate material; providing an amount of a radiation absorbent material over a selected surface portion of the layer of particulate material; providing an amount of a material that comprises a plurality of elongate elements over at least part of the selected surface portion of the layer of particulate material; and providing radiation across the selected surface portion of the layer of particulate material so as to sinter a portion of the material of the layer including causing the plurality of elongate elements to become embedded in the sintered portion of material; characterized in that the elongate elements are selected from the group of elongate elements consisting of carbon nanotubes and elongate graphene plates; and in that the method further comprises providing the elongate elements over at least part of the selected surface portion of the layer of particulate material comprises ejecting, from a printing device, the elongate elements as the printing device moves over the selected surface portion of the layer of particulate material, thereby aligning the elongate elements in a direction of travel of the printing device. providing a layer of particulate material; providing an amount of a radiation absorbent material over a selected surface portion of the layer of particulate material; providing an amount of a material that comprises a plurality of elongate elements over at least part of the selected surface portion of the layer of particulate material; and providing radiation across the selected surface portion of the layer of particulate material so as to sinter a portion of the material of the layer including causing the plurality of elongate elements to become embedded in the sintered portion of material; characterized in that the elongate elements are selected from the group of elongate elements consisting of carbon nanotubes and elongate graphene plates; and in that the method further comprises providing the elongate elements over at least part of the selected surface portion of the layer of particulate material comprises ejecting, from a printing device, the elongate elements as the printing device moves over the selected surface portion of the layer of particulate material, thereby aligning the elongate elements in a direction of travel of the printing device.
Turbine engine, such as an aircraft turbofan or a turboprop, comprising a device for monitoring a high-pressure pump in a engine fuel supply circuit, said circuit comprising a pressurising and shut-off valve which is regulated at a predetermined pressure threshold and which is mounted between a fuel flow regulating valve and a supply duct of the injectors, and means for measuring the rotational speed of the turbine engine, characterised in that it comprises means for detecting the opening of the pressurising and shut-off valve, means for recording the measured value of the rotational speed of the turbine engine at the opening of the pressurising and shut-off valve, and means for comparing this measured value with a predetermined threshold, in order to propose the replacement of the high-pressure pump when the recorded value of the rotational speed reaches the predetermined threshold.
A fabric for an air-bag comprising interwoven sets of warp and weft yarns, wherein the yarns of a first sets of yarns are tape-like, having a width/depth ratio of at least 1.5, and the yarns of a second set of yarns are not tape-like and have a width-depth ratio less than 1.5, wherein the first set of yarns comprises monofilament tape elements; and wherein the first set of yarns is formed from multiple layers of material, with one of the layers comprising a layer of a base polymer.
Device for treating fluid mixtures that contain gases, in particular such as hydrogen (H 2), air, nitrogen (N 2) or natural gases, and liquids, in particular such as ionic liquids, hydraulic oil or process liquids, comprising at least one first separation stage for separating the fluid mixture into a liquid portion and a gas portion that is contaminated with a residual liquid portion, from which this residual liquid portion is cleaned in at least one further separation stage, a centrifugal separator being provided as a first separation stage, characterised in that an inner wall of a cyclone housing of the centrifugal separator delimits, at the lower end of said centrifugal separator adjacent to a collection chamber, an annular opening between a pipe section concentric to a vertical axis of a housing, said annular opening forming a connection between the region of the cylindrical cyclone housing that is furthest from the axis and the collection chamber.
An agricultural mobile system configured to perform one or more in-season management task on an agricultural field while autonomously navigating between adjacent rows of planted crops, based at least in part on an increased data collection range of one or more aerial navigation sensors, the agricultural mobile system comprising: an unmanned mobile vehicle platform dimensioned so as to enable traversal between adjacent rows of planted crops on an agricultural field, the unmanned mobile vehicle platform including a navigation module configured to receive data collected by one or more external aerial navigation sensors for aid in at least one of navigating the unmanned mobile vehicle platform between adjacent rows of planted crops and avoiding obstacles, while performing the one or more in-season management task; and an aerial vehicle comprising the one or more external aerial navigation sensors and configured to collect a range of data related to the navigational condition of the agricultural field. an unmanned mobile vehicle platform dimensioned so as to enable traversal between adjacent rows of planted crops on an agricultural field, the unmanned mobile vehicle platform including a navigation module configured to receive data collected by one or more external aerial navigation sensors for aid in at least one of navigating the unmanned mobile vehicle platform between adjacent rows of planted crops and avoiding obstacles, while performing the one or more in-season management task; and an aerial vehicle comprising the one or more external aerial navigation sensors and configured to collect a range of data related to the navigational condition of the agricultural field.
A tire comprising: a tread portion comprising a middle land region defined between a middle circumferential groove and an axially outer shoulder circumferential groove, the middle land region circumferentially divided by middle lateral grooves into a plurality of middle blocks each having a block side wall and a block tread, and each of the middle lateral grooves comprising a first portion extending from the shoulder circumferential groove, a second portion located on the middle circumferential groove side and inclined with respect to the first portion, and a connect portion at which the first portion and the second portion are connected with each other, so that each of the middle blocks is provided with a convex corner portion which is convex toward the outside of the block at the connect portion, wherein in the convex corner portion, the block side wall comprises a first side wall extending along the first portion, and a second side wall extending along the second portion, characterized in that in the convex corner portion, the block side wall further comprises a substantially triangular third side wall intersecting the first side wall, the second side wall and the block tread, wherein the third side wall terminates on the outside in the tire radial direction, of the groove bottom of the middle lateral groove. a tread portion comprising a middle land region defined between a middle circumferential groove and an axially outer shoulder circumferential groove, the middle land region circumferentially divided by middle lateral grooves into a plurality of middle blocks each having a block side wall and a block tread, and each of the middle lateral grooves comprising a first portion extending from the shoulder circumferential groove, a second portion located on the middle circumferential groove side and inclined with respect to the first portion, and a connect portion at which the first portion and the second portion are connected with each other, so that each of the middle blocks is provided with a convex corner portion which is convex toward the outside of the block at the connect portion, wherein a first portion extending from the shoulder circumferential groove, a second portion located on the middle circumferential groove side and inclined with respect to the first portion, and a connect portion at which the first portion and the second portion are connected with each other, so that each of the middle blocks is provided with a convex corner portion which is convex toward the outside of the block at the connect portion, wherein in the convex corner portion, the block side wall comprises a first side wall extending along the first portion, and a second side wall extending along the second portion, characterized in that in the convex corner portion, the block side wall further comprises a substantially triangular third side wall intersecting the first side wall, the second side wall and the block tread, wherein the third side wall terminates on the outside in the tire radial direction, of the groove bottom of the middle lateral groove.
A method for performing multi-sampling for anti-aliasing, comprising using a sample grid of a non-power-of-two dimension per pixel to sample a polygon; distributing a non-power-of-two plurality of sub-samples within the sample grid; creating a bounding box whose size is less than the size of said sample grid; wherein the sub-samples are distributed within the bounding box; and wherein the bounding box guarantees that, if a polygon to be rendered crosses the boundary of the bounding box, the polygon covers at least one sub-sample.
An in vitro method for screening a candidate compound for use as a drug for the prevention and treatment of neurological disorders involving Tau dysfunction comprising the following steps: a) determining the ability of the candidate compound, to enhance the interaction between a Tau polypeptide and a FKBP52 polypeptide and b) selecting positively the candidate compound if the candidate compound enhances said interaction. a) determining the ability of the candidate compound, to enhance the interaction between a Tau polypeptide and a FKBP52 polypeptide and b) selecting positively the candidate compound if the candidate compound enhances said interaction.
Method for monitoring and controlling sample preparation, sample purification and/or sample fractionation of biological samples and chemical labelling reactions and antibody reactions in a sample containing proteins, comprising the following steps: i. adding a control protein to the sample, which control protein has been labelled prior to addition to the sample, ii. optionally steps of sample preparation, for example protein precipitations, iii. labelling the at least one target protein and the labelled control protein, preferably with a fluorescent dye, in the sample, iv. fractionating the proteins in the sample by means of gel electrophoresis to separate the at least one labelled target protein and the twice labelled control protein, v. detecting and/or quantifying the at least one target protein and the labelled control protein, vi. normalizing the quantified amount and/or concentration and/or the migration behaviour/separating path of and/or quantifying absolutely the at least one target protein based on the known amount and/or concentration and/or the migration behaviour/separating path of the labelled control protein in the sample, characterized in that the control protein is labelled twice during labelling of the target protein and the control protein is labelled with different dyes. i. adding a control protein to the sample, which control protein has been labelled prior to addition to the sample, ii. optionally steps of sample preparation, for example protein precipitations, iii. labelling the at least one target protein and the labelled control protein, preferably with a fluorescent dye, in the sample, iv. fractionating the proteins in the sample by means of gel electrophoresis to separate the at least one labelled target protein and the twice labelled control protein, v. detecting and/or quantifying the at least one target protein and the labelled control protein, vi. normalizing the quantified amount and/or concentration and/or the migration behaviour/separating path of and/or quantifying absolutely the at least one target protein based on the known amount and/or concentration and/or the migration behaviour/separating path of the labelled control protein in the sample,