mhurhangee/ep-ind-claims huggingface dataset:
A helmet comprising: an outer shell comprising an inner surface, an outer surface, and an outer shell lower edge extending between the inner surface and the outer surface, an energy management liner adjacent to the inner surface of the outer shell, characterized in that: the outer shell further comprises at least two shoulder pad recesses positioned at a lower edge of the outer shell on a respective left and right sides of the helmet; and and the energy management liner comprises at least two shoulder pads formed of a foamed energy management material, each of the at least two shoulder pads received into one of the at least two shoulder pad recesses on the respective left or right side of the helmet, each shoulder pad extending from inside of the outer shell to across at least a majority of a width of the lower edge of the outer shell. an outer shell comprising an inner surface, an outer surface, and an outer shell lower edge extending between the inner surface and the outer surface, an energy management liner adjacent to the inner surface of the outer shell, characterized in that: the outer shell further comprises at least two shoulder pad recesses positioned at a lower edge of the outer shell on a respective left and right sides of the helmet; and and the energy management liner comprises at least two shoulder pads formed of a foamed energy management material, each of the at least two shoulder pads received into one of the at least two shoulder pad recesses on the respective left or right side of the helmet, each shoulder pad extending from inside of the outer shell to across at least a majority of a width of the lower edge of the outer shell. the outer shell further comprises at least two shoulder pad recesses positioned at a lower edge of the outer shell on a respective left and right sides of the helmet; and and the energy management liner comprises at least two shoulder pads formed of a foamed energy management material, each of the at least two shoulder pads received into one of the at least two shoulder pad recesses on the respective left or right side of the helmet, each shoulder pad extending from inside of the outer shell to across at least a majority of a width of the lower edge of the outer shell.
A method of preparing (R,S)-nicotine, comprising: reacting a nicotinate ester with N-vinyl-2-pyrrolidinone in the presence of a base and a solvent to form a first mixture; combining the first mixture with an acid to form a second mixture comprising an aqueous layer; separating the aqueous layer from the second mixture; combining the separated aqueous layer with an acid to form a third mixture; combining the third mixture with a base to form a fourth mixture comprising myosmine; reducing the myosmine to nornicotine using a reducing agent; and methylating the nornicotine to yield R,S-nicotine. reacting a nicotinate ester with N-vinyl-2-pyrrolidinone in the presence of a base and a solvent to form a first mixture; combining the first mixture with an acid to form a second mixture comprising an aqueous layer; separating the aqueous layer from the second mixture; combining the separated aqueous layer with an acid to form a third mixture; combining the third mixture with a base to form a fourth mixture comprising myosmine; reducing the myosmine to nornicotine using a reducing agent; and methylating the nornicotine to yield R,S-nicotine.
A blood clot removal device for removing blood clots from the vascular system of a patient, the blood clot removal device being implantable in the patient's body and comprising: a blood flow passageway having a first side wall and a second side wall, a filter provided in the blood flow passageway for filtering blood clots, and a cleaning device for cleaning the filter, characterised in that the cleaning device is adapted to move from the first side wall towards the second side wall to move blood clots away from the blood flow passageway. a blood flow passageway having a first side wall and a second side wall, a filter provided in the blood flow passageway for filtering blood clots, and a cleaning device for cleaning the filter, characterised in that the cleaning device is adapted to move from the first side wall towards the second side wall to move blood clots away from the blood flow passageway.
A rewritable data storage medium, having a rewritable recording layer provided with a tracking structure having tracks, said layer having a data recording area, and an erasable identification mark forming a bar code, written using the same or the inverse property change of the recording layer as is used for user data recording, and which is present in an identification mark area other than the data recording area and which extends over a radial width corresponding to the radial width of several tracks of the tracking structure in the data recording area characterized in that the data recording area has a first tracking structure, whereas the identification mark area has a second tracking structure (8") modified from the first tracking structure.
An adapter (1, 2) for connecting air ducts to a ventilation device, an air distribution device and/or the like, comprising a base body formed in one piece and comprising a plurality of channels (6, 7, 8, 9) which are fluidically separated from each other and which extend through the base body, wherein each channel (6, 7, 8, 9) comprises a first port and a second port (4, 5), wherein each first port is configured for being connected to a ventilation device, an air distribution device and/or the like, and wherein each second port (4, 5) is configured for arranging an air duct, characterized in that the channels (6, 7, 8, 9) extend transversely with respect to each other at least in some sections and that the base body tapers from the first ports in the direction of the second ports (4, 5).
A drive unit for a drive train of an electrically driven motor vehicle, in particular a hybrid motor vehicle, having a first electric rotary machine and a second electric rotary machine and a first shaft and a second shaft, wherein a rotor of the first electric rotary machine is connected in a rotationally fixed manner to the first shaft and a rotor of the second electric rotary machine is connected in a rotationally fixed manner to the second shaft, and wherein the drive unit further comprises a separating clutch with which the rotor of the first electric rotary machine can be or is connected to the second shaft for torque transmission, wherein one of the two electric rotary machines (10, 20) is arranged, at least in regions, radially and axially within a space radially delimited by the other electric rotary machine (10, 20), the separating clutch is connected with its input side to the first shaft, and with its output side, to the second shaft, the drive unit has a second transmission stage which is formed by a toothing of the second shaft and a first gear which meshes with the toothing of the second shaft, a torque provided by the rotor of the first electric rotary machine is transmitted via the second transmission stage when the separating clutch is closed, and wherein the two shafts (40, 41) are arranged coaxially, the second shaft is designed as a hollow shaft and the first shaft runs in sections within the second shaft, characterized in that the separating clutch is designed as a multi-plate clutch, the input side of which is formed by inner plates, which are arranged axially next to the rotor of the first electric rotary machine on the first shaft, and outer plates of the separating clutch are connected to the second shaft as its output side. wherein one of the two electric rotary machines (10, 20) is arranged, at least in regions, radially and axially within a space radially delimited by the other electric rotary machine (10, 20), the separating clutch is connected with its input side to the first shaft, and with its output side, to the second shaft, the drive unit has a second transmission stage which is formed by a toothing of the second shaft and a first gear which meshes with the toothing of the second shaft, a torque provided by the rotor of the first electric rotary machine is transmitted via the second transmission stage when the separating clutch is closed, and wherein the two shafts (40, 41) are arranged coaxially, the second shaft is designed as a hollow shaft and the first shaft runs in sections within the second shaft, characterized in that the separating clutch is designed as a multi-plate clutch, the input side of which is formed by inner plates, which are arranged axially next to the rotor of the first electric rotary machine on the first shaft, and outer plates of the separating clutch are connected to the second shaft as its output side.
A composition comprising an NGly1 inhibitor for use in treating cancer, wherein the NGly1 inhibitor is effective to reduce expression of a cancer cell proteasome, further wherein the number of viable cancer cells is reduced, optionally wherein the composition further comprises a pharmaceutically acceptable carrier.
A composition for use in a method for treating a blood disorder or hematological or solid malignancy in a human subject, the method comprising administering the composition to the subject, wherein the composition is for oral administration and comprises a therapeutically effective amount of decitabine and tetrahydrouridine, wherein the tetrahydrouridine is bio-available 30 to 60 minutes before the decitabine, wherein the composition is effective to result in a peak level decitabine plasma concentration no greater than 0.5 μM in the subject.
A fuel pipe structure for a motorcycle connecting a fuel pump joint pipe to a fuel supply tube with a quick connector, the structure comprising: a protective cover covering at least a part of a connection between the joint pipe and the fuel supply tube; wherein the protective cover includes a fitting portion (102, 103) fitting on and accommodating at least the joint pipe and the quick connector; an outer peripheral surface of the quick connector includes two planes formed thereon; and the protective cover includes a structure designed to clamp the planes preventing the quick connector from being rotated relative to the joint pipe, characterised in that the protective cover includes opposing ribs formed on side wall portions for clamping the planes. a protective cover covering at least a part of a connection between the joint pipe and the fuel supply tube; wherein the protective cover includes a fitting portion (102, 103) fitting on and accommodating at least the joint pipe and the quick connector; an outer peripheral surface of the quick connector includes two planes formed thereon; and the protective cover includes a structure designed to clamp the planes preventing the quick connector from being rotated relative to the joint pipe, characterised in that the protective cover includes opposing ribs formed on side wall portions for clamping the planes.
A biodegradable polyester composition, characterized in that, it comprises following components in parts by weight: i) 60 to 99 parts of biodegradable aliphatic-aromatic polyester; ii) 0 to 40 parts of polylactic acid; iii) 0 to 30 parts of an organic filler and/or an inorganic filler; iv) 0 to 1 part of a copolymer which contains epoxy group and is based on styrene, acrylate and/or methacrylate, wherein based on a total weight of the biodegradable polyester composition, a weight content of cyclopentanone is 0.5ppm-85ppm, preferably 5ppm-50ppm, more preferably 10ppm-35ppm, the weight content of the cyclopentanone being measured as disclosed in the description. i) 60 to 99 parts of biodegradable aliphatic-aromatic polyester; ii) 0 to 40 parts of polylactic acid; iii) 0 to 30 parts of an organic filler and/or an inorganic filler; iv) 0 to 1 part of a copolymer which contains epoxy group and is based on styrene, acrylate and/or methacrylate,
A method for the recovery of metals from a feed stream containing one or more value metals and lithium, the method comprising: subjecting the feed stream to a sulphuric acid leach to form a slurry comprising a pregnant leach solution of soluble metal salts and a solid residue; separating the pregnant leach solution and the solid residue; subjecting the pregnant leach solution to a precipitation step to remove iron and aluminium, the precipitation step comprising the addition of ammonia to increase the pH of the pregnant leach solution to above 4.5: subjecting the pregnant leach solution to one or more separate solvent extraction steps, wherein each solvent extraction step recovers one or more value metals from the pregnant leach solution and where each solvent extraction step comprises the dosing of the pregnant leach solution with ammonia to maintain a target pH, the remaining pregnant leach solution comprising lithium recovery of lithium from the pregnant leach solution; and following the step of lithium recovery, the leach solution is subjected to an ammonium sulphate recovery step. subjecting the feed stream to a sulphuric acid leach to form a slurry comprising a pregnant leach solution of soluble metal salts and a solid residue; separating the pregnant leach solution and the solid residue; subjecting the pregnant leach solution to a precipitation step to remove iron and aluminium, the precipitation step comprising the addition of ammonia to increase the pH of the pregnant leach solution to above 4.5: subjecting the pregnant leach solution to one or more separate solvent extraction steps, wherein each solvent extraction step recovers one or more value metals from the pregnant leach solution and where each solvent extraction step comprises the dosing of the pregnant leach solution with ammonia to maintain a target pH, the remaining pregnant leach solution comprising lithium recovery of lithium from the pregnant leach solution; and following the step of lithium recovery, the leach solution is subjected to an ammonium sulphate recovery step. subjecting the pregnant leach solution to one or more separate solvent extraction steps, wherein each solvent extraction step recovers one or more value metals from the pregnant leach solution and where each solvent extraction step comprises the dosing of the pregnant leach solution with ammonia to maintain a target pH, the remaining pregnant leach solution comprising lithium recovery of lithium from the pregnant leach solution; and following the step of lithium recovery, the leach solution is subjected to an ammonium sulphate recovery step.
Use of a low dose of IL-6, or a mutein, isoform, fused protein, functional derivative, active fraction or circularly permutated derivative or a salt thereof, for the manufacture of a medicament for the prevention of chemotherapy-induced peripheral neuropathy, wherein the chemotherapy-induced peripheral neuropathy is caused by at least one chemotherapeutic agent, wherein the medicament is to be administered during the chemotherapy, and wherein the dose of IL-6, or a mutein, isoform, fused protein, functional derivative, active fraction or circularly permutated derivative or a salt thereof, is in the range of 4 to 210 μg.
A compound, or pharmaceutically acceptable salt thereof, comprising a vascular disrupting agent selected from colchicine, azademethylcolchicine, azacolchicine, N-methyl desacetylcolchicine and desacetylcolchicine linked to a peptide comprising a membrane-type matrix metalloproteinase (MT-MMP) proteolytic cleavage site comprising the amino acid sequence -Arg-Ser-Cit-Gly-Hof-Tyr-Leu-.
An apparatus, comprising: a substrate made of an optical material having a first surface and a second surface; and a single three-dimensional diffractive element comprising a plurality of pixels disposed on the substrate, said three-dimensional diffractive element comprises: at least one area configured to receive an input optical beam, and at least one further area configured to provide at least one output optical beam with an exit pupil expanded in two dimensions, wherein the three-dimensional diffractive element has a matching x-direction pixel period in the at least one area and the at least one further area, wherein the three-dimensional diffractive element has a matching y-direction pixel period in the at least one area and the at least one further area, wherein at least part of the input optical beam is diffracted in said at least one area to provide at least one optical beam substantially within the first and second surfaces, and at least part of the at least one optical beam is further coupled out of the first or the second surface of the substrate by diffraction in said at least one further area to provide said at least one output optical beam. a substrate made of an optical material having a first surface and a second surface; and a single three-dimensional diffractive element comprising a plurality of pixels disposed on the substrate, said three-dimensional diffractive element comprises: at least one area configured to receive an input optical beam, and at least one further area configured to provide at least one output optical beam with an exit pupil expanded in two dimensions, at least one area configured to receive an input optical beam, and at least one further area configured to provide at least one output optical beam with an exit pupil expanded in two dimensions, wherein the three-dimensional diffractive element has a matching x-direction pixel period in the at least one area and the at least one further area, wherein the three-dimensional diffractive element has a matching y-direction pixel period in the at least one area and the at least one further area, wherein at least part of the input optical beam is diffracted in said at least one area to provide at least one optical beam substantially within the first and second surfaces, and at least part of the at least one optical beam is further coupled out of the first or the second surface of the substrate by diffraction in said at least one further area to provide said at least one output optical beam.
Internal combustion engine made up of three cylinders in which there moves a piston in collaboration with a combustion chamber, whereby the said combustion chamber comprises a single intake valve, a single exhaust valve, a single fuel injector arranged in the combustion chamber, two spark plugs (Al), and means for creating a flow inside of the said chamber, "swumble", namely a movement whereby the air rotates about the axis of the cylinder combined with a movement of rotation about an axis perpendicular to the axis of the said cylinder, the said "swumble" flow creating means comprising the shape of the intake duct and of the combustion chamber and the relative positioning of the injector and of the spark plugs, and whereby, for two consecutive cylinders, the layout of the intake valve, of the exhaust valve, of the fuel injector and of the two spark plugs is symmetrical about a plane separating two consecutive combustion chambers.
Nuclear reactor, comprising a vessel, a reaction chamber located in the vessel, nuclear fuel contained in the reaction chamber, wherein said nuclear reactor comprises a radiation source suitable for providing electromagnetic radiations to the nuclear fuel contained in the reaction chamber, wherein the nuclear fuel comprises a colloidal mixture, characterized in that said nuclear fuel is capable of producing Ultra Low Momentum Neutrons (ULMNs) when subjected to said electromagnetic radiations, the wavelength of which is on the order of 1 to 10 micrometres and the nuclear fuel comprises particles with a radius similar to the wavelength of said electromagnetic radiations, wherein said Ultra Low Momentum Neutrons are suitable for capture by the nuclei of the nuclear fuel.
A fast roll-up door for closing an aperture, said roll-up door comprising: (a) a curtain having two opposite and parallel lateral edges extending along a longitudinal direction, and two opposite end edges joining the lateral edges, the curtain comprising a continuous bead extending parallel and adjacent to each of the two lateral edges, said continuous beads being held in, (b) a pair of elongated guiding rails suitable for interacting with the continuous beads of the lateral edges of the curtain, for holding said lateral edges, and for guiding them as the curtain is being wound or unwound about a rotating axle, X1, characterized in that, the curtain comprises a plurality of windows of same geometry and evenly distributed along a line adjacent and parallel to at least one of the continuous beads of the curtain and in that, the roll-up door further comprises a speed device for detecting and monitoring during the winding and unwinding of the curtain about the rotating axle, X1, of the time sequence of passage of the windows before a fixed point, and thus for determining the instantaneous translation speed of the curtain along the guiding rails. (a) a curtain having two opposite and parallel lateral edges extending along a longitudinal direction, and two opposite end edges joining the lateral edges, the curtain comprising a continuous bead extending parallel and adjacent to each of the two lateral edges, said continuous beads being held in, (b) a pair of elongated guiding rails suitable for interacting with the continuous beads of the lateral edges of the curtain, for holding said lateral edges, and for guiding them as the curtain is being wound or unwound about a rotating axle, X1,
An X-ray fluoroscopic imaging system, characterized in that, comprising: an inspection passage through which an inspected object is passed; an electron accelerator comprising an electron accelerating unit, an electron emitting unit and a target, the electron beam coming from the electron emitting unit and accelerated by the electron accelerating unit bombarding the target to generate X-rays at a target point (page 11, I 33 - page 12, line 9); a shielding collimator apparatus comprising a shielding structure, and a first collimator for extracting a lower energy planar sector X-ray beam and a second collimator for extracting a higher energy planar sector X-ray beam which are disposed within the shielding structure; a lower energy detector array for receiving the X-ray beam from the first collimator; a higher energy detector array for receiving the X-ray beam from the second collimator; wherein the shielding structure surrounds the target; wherein the first collimator, the lower energy detector array and the target point bombarded by the electron beam are located in a first plane; and wherein the second collimator, the higher energy detector array and the target point bombarded by the electron beam are located in a second plane. an inspection passage through which an inspected object is passed; an electron accelerator comprising an electron accelerating unit, an electron emitting unit and a target, the electron beam coming from the electron emitting unit and accelerated by the electron accelerating unit bombarding the target to generate X-rays at a target point (page 11, I 33 - page 12, line 9); a shielding collimator apparatus comprising a shielding structure, and a first collimator for extracting a lower energy planar sector X-ray beam and a second collimator for extracting a higher energy planar sector X-ray beam which are disposed within the shielding structure; a lower energy detector array for receiving the X-ray beam from the first collimator; a higher energy detector array for receiving the X-ray beam from the second collimator; wherein the shielding structure surrounds the target; wherein the first collimator, the lower energy detector array and the target point bombarded by the electron beam are located in a first plane; and wherein the second collimator, the higher energy detector array and the target point bombarded by the electron beam are located in a second plane.