mhurhangee/ep-ind-claims huggingface dataset:
A method comprising: generating a set of digital signals (405, 406, 407, 408) representative of a constellation point, each dimension of the constellation point being uniquely represented by m bits, wherein m ∈ 11, 2, 3}; applying a linear polyphase filter to a digital signal of the set, the linear polyphase filter configured to pre-compensate for a linear transfer function of an electro-optic path of the digital signal and to generate a first filtered signal having a roll-off factor α, wherein α is a positive real number satisfying α ≤ 1; applying a nonlinear polyphase filter to the digital signal, in parallel to applying the linear polyphase filter to the digital signal, the nonlinear polyphase filter configured to generate a second filtered signal representative of nonlinear noise in the electro-optic path; calculating a pre-compensated digital signal (413, 414, 415, 416, 507) from a difference between the first filtered signal and the second filtered signal; and transmitting an optical signal based on the pre-compensated digital signal. generating a set of digital signals (405, 406, 407, 408) representative of a constellation point, each dimension of the constellation point being uniquely represented by m bits, wherein m ∈ 11, 2, 3}; applying a linear polyphase filter to a digital signal of the set, the linear polyphase filter configured to pre-compensate for a linear transfer function of an electro-optic path of the digital signal and to generate a first filtered signal having a roll-off factor α, wherein α is a positive real number satisfying α ≤ 1; applying a nonlinear polyphase filter to the digital signal, in parallel to applying the linear polyphase filter to the digital signal, the nonlinear polyphase filter configured to generate a second filtered signal representative of nonlinear noise in the electro-optic path; calculating a pre-compensated digital signal (413, 414, 415, 416, 507) from a difference between the first filtered signal and the second filtered signal; and transmitting an optical signal based on the pre-compensated digital signal.
A compound of formula: wherein R 1 is selected from the group consisting of hydrogen, methyl and cyclopropylmethyl; AA-COOH is an amino acid selected from the group consisting of 2-amino-2-adamantane carboxylic acid, cyclohexylglycine and 9-amino-bicyclo[3.3.1]nonane-9-carboxylic acid; R 2 is selected from the group consisting of (C 1 -C 6)alkyl, (C 3 -C 8)cycloalkyl, (C 3 -C 8)cycloalkylmethyl, halogen, nitro and trifluoromethyl; ALK is (C 2 -C 5)alkylidene; R 3, R 4 and R 5 are each and independently selected from the group consisting of hydrogen and (C 1 -C 4)alkyl under the proviso that one of R 3, R 4 and R 5 is of the following formula wherein ALK' is (C 2 -C 5)alkylidene; R 6 is selected from the group consisting of hydrogen and (C 1 -C 4)alkyl; and R 7 is an Effector moiety, wherein the Effector moiety is comprising or capable of comprising an Effector, wherein the Effector is selected from the group consisting of a diagnostically active nuclide, a therapeutically active nuclide and a combination thereof; or a pharmaceutically acceptable salt, solvate or hydrate thereof. R 1 is selected from the group consisting of hydrogen, methyl and cyclopropylmethyl; AA-COOH is an amino acid selected from the group consisting of 2-amino-2-adamantane carboxylic acid, cyclohexylglycine and 9-amino-bicyclo[3.3.1]nonane-9-carboxylic acid; R 2 is selected from the group consisting of (C 1 -C 6)alkyl, (C 3 -C 8)cycloalkyl, (C 3 -C 8)cycloalkylmethyl, halogen, nitro and trifluoromethyl; ALK is (C 2 -C 5)alkylidene; R 3, R 4 and R 5 are each and independently selected from the group consisting of hydrogen and (C 1 -C 4)alkyl under the proviso that one of R 3, R 4 and R 5 is of the following formula wherein ALK' is (C 2 -C 5)alkylidene; R 6 is selected from the group consisting of hydrogen and (C 1 -C 4)alkyl; and R 7 is an Effector moiety, wherein the Effector moiety is comprising or capable of comprising an Effector, wherein the Effector is selected from the group consisting of a diagnostically active nuclide, a therapeutically active nuclide and a combination thereof; ALK' is (C 2 -C 5)alkylidene; R 6 is selected from the group consisting of hydrogen and (C 1 -C 4)alkyl; and R 7 is an Effector moiety, wherein the Effector moiety is comprising or capable of comprising an Effector, wherein the Effector is selected from the group consisting of a diagnostically active nuclide, a therapeutically active nuclide and a combination thereof; or a pharmaceutically acceptable salt, solvate or hydrate thereof.
A system for treating ballast water in ballast tanks onboard vessels and offshore constructions, said system comprising: - one or more ballast tanks, - a circulation pump circulating or recirculating, via a tubing, ballast water from and to the one or more ballast tanks; - a nitrogen and/or carbon dioxide generator which is connected to the tubing in such a manner that nitrogen and/or carbon dioxide can be supplied to the ballast water; and - one or more nozzle heads that are functionally connected to the tubing and is/are arranged in one or more ballast tanks, said one or more nozzle heads comprising at least one nozzle for injection of the gas-containing water into the one or more ballast tanks; characterised in that at least one nozzle is configured for powered rotation about a first axis. - one or more ballast tanks, - a circulation pump circulating or recirculating, via a tubing, ballast water from and to the one or more ballast tanks; - a nitrogen and/or carbon dioxide generator which is connected to the tubing in such a manner that nitrogen and/or carbon dioxide can be supplied to the ballast water; and - one or more nozzle heads that are functionally connected to the tubing and is/are arranged in one or more ballast tanks, said one or more nozzle heads comprising at least one nozzle for injection of the gas-containing water into the one or more ballast tanks;
An orthopedic instrument for implanting an acetabular cup having a surface for attachment to an acetabular socket in a pelvic bone and a concave surface having an acetabular cup stem affixed therein and projecting outwardly therefrom, the concave surface further comprising a circumferential groove located in proximity to a circumferential edge of the acetabular cup, the orthopedic instrument comprising a handle comprising a shaft having an impactor head at a proximal end and an axially disposed first threaded annular portion at a distal end, an acetabular impactor having a hemispherical head at a distal end and an axially disposed second threaded annular portion at a proximal end, the second threaded annular portion being screwed into the first threaded annular portion removably affixing the handle to the acetabular impactor, the hemispherical head being configured to couple to the acetabular cup, characterized in that the hemispherical head comprises an annular recess to receive the acetabular cup stem, and in that the hemispherical head furthermore comprises retaining tabs configured to releasably engage the circumferential groove.
A method for sensing an image of a specimen, comprising: receiving light energy from the specimen, and applying the light energy to a sensor comprising at least one pixel (300, 400) having a storage well gate, characterised in that it additionally comprises determining a value of a variable gate voltage that reduces the effects of aliasing and applying the variable gate voltage to said storage well gate of each pixel (300, 400), in order to adjust a modulated transfer function of the pixel (300, 400). receiving light energy from the specimen, and applying the light energy to a sensor comprising at least one pixel (300, 400) having a storage well gate, characterised in that it additionally comprises determining a value of a variable gate voltage that reduces the effects of aliasing and applying the variable gate voltage to said storage well gate of each pixel (300, 400), in order to adjust a modulated transfer function of the pixel (300, 400).
A pouch assembly containing a liquid being an aqueous urea solution for use in a selective catalytic reduction system for treating exhaust gases of an internal combustion engine of a vehicle and for transferring the liquid to a liquid tank of the vehicle, the pouch assembly comprising a flexible pouch and a spout attached thereto, wherein at least a part of the spout extends outside the flexible pouch and is arranged to dispense the liquid contained in the flexible pouch into the liquid tank of the vehicle via a tank filling neck configured to receive the spout, wherein the spout comprises - a base having an elongated axial through-passage to serve as a discharge passage for the liquid, the base extending axially through an opening provided in a wall of the pouch and being attached to the opening, and - a top end having an elongated axial through-passage in fluid connection with the base elongated axial through-passage, the top end configured for insertion into the filling neck of the liquid tank for transfer of the liquid into the liquid tank; wherein the spout further comprises a body that - extends between the base and the top end of the spout, - has an elongated shape, - has an elongated axial through-passage in fluid connection with base and top end elongated axial through-passages (211, 221), and - is configured to at least partially extend into the tank filling neck of the liquid tank for the transfer of liquid into the liquid tank; wherein the top end has a maximum outer diameter (D 1) that is equal to or less than 97 % of the diameter of the inner inside passage of the tank filling neck at its narrowest whereby the filling neck is defined in accordance with ISO 22241 and wherein the body has a length (L 1) that is between 4 and 12 times the length (L 2) of the base of the spout, and is between 2 and 6 times the length (L 3) of the top end of the spout. - a base having an elongated axial through-passage to serve as a discharge passage for the liquid, the base extending axially through an opening provided in a wall of the pouch and being attached to the opening, and - a top end having an elongated axial through-passage in fluid connection with the base elongated axial through-passage, the top end configured for insertion into the filling neck of the liquid tank for transfer of the liquid into the liquid tank; - extends between the base and the top end of the spout, - has an elongated shape, - has an elongated axial through-passage in fluid connection with base and top end elongated axial through-passages (211, 221), and - is configured to at least partially extend into the tank filling neck of the liquid tank for the transfer of liquid into the liquid tank;
A medical catheter (102, 148, 300, 350, 410, 450, 550, 602, 604, 654) for performing a medical operation on an organic lumen, the catheter (102, 148, 300, 350, 410, 450, 550, 602, 604, 654) comprising: an elongated tubular member defining a lumen (116, 162, 322, 362, 428, 464, 666) wherein said lumen is a guidewire lumen (116, 162, 322, 362, 428, 464, 666) for a guidewire (104, 320, 360, 426, 578, 606, 608, 674) to pass through said guidewire lumen (116, 162, 322, 362, 428, 464, 666) a medical operational element (120, 154, 310, 420, 558, 612, 616, 646) located at a distal end of said elongated tubular member (108, 152, 302, 352, 412, 452, 552, 660); an electromagnetic field detector (114, 156, 304, 414, 454, 554, 614, 618, 662) located at said distal end, and a wiring (136, 142, 158, 306, 308, 354, 356, 418, 456, 556, 620, 622, 672) for coupling said electromagnetic field detector with (114, 156, 304, 414, 454, 554, 614, 618, 662) a medical positioning system (106, 150, 610, 656), characterized in that said electromagnetical field detector (114, 156, 304, 414, 454, 554, 614, 618, 662) being in form of a coil which surrounds at least a portion of said lumen (116, 162, 322, 362, 428, 464, 666). an elongated tubular member defining a lumen (116, 162, 322, 362, 428, 464, 666) wherein said lumen is a guidewire lumen (116, 162, 322, 362, 428, 464, 666) for a guidewire (104, 320, 360, 426, 578, 606, 608, 674) to pass through said guidewire lumen (116, 162, 322, 362, 428, 464, 666) a medical operational element (120, 154, 310, 420, 558, 612, 616, 646) located at a distal end of said elongated tubular member (108, 152, 302, 352, 412, 452, 552, 660); an electromagnetic field detector (114, 156, 304, 414, 454, 554, 614, 618, 662) located at said distal end, and a wiring (136, 142, 158, 306, 308, 354, 356, 418, 456, 556, 620, 622, 672) for coupling said electromagnetic field detector with (114, 156, 304, 414, 454, 554, 614, 618, 662) a medical positioning system (106, 150, 610, 656), characterized in that said electromagnetical field detector (114, 156, 304, 414, 454, 554, 614, 618, 662) being in form of a coil which surrounds at least a portion of said lumen (116, 162, 322, 362, 428, 464, 666).
System having a control device of a work light of a work machine, in particular of an agricultural work machine, wherein the system comprises: - the work machine having at least one work light, which is provided to illuminate a work region to be monitored by a user of the work machine - a functional machine, in particular an agricultural functional machine, to be functionally coupled with the work machine - control means for controlling the operation of the work light - a data storage device, which is equipped to store an illumination profile, wherein the illumination profile comprises data and/or instructions, which are provided for transmission to the control means and the control means direct the at least one work light to illuminate the work region corresponding to the illumination profile, characterised in that the data storage device is equipped to store different illumination profiles, which are assigned to different users of the system. - the work machine having at least one work light, which is provided to illuminate a work region to be monitored by a user of the work machine - a functional machine, in particular an agricultural functional machine, to be functionally coupled with the work machine - control means for controlling the operation of the work light - a data storage device, which is equipped to store an illumination profile, wherein the illumination profile comprises data and/or instructions, which are provided for transmission to the control means and the control means direct the at least one work light to illuminate the work region corresponding to the illumination profile,
A method for performing measurements of discovery signals, the method being performed by a terminal and comprising: receiving, information on discovery signals from a primary cell, wherein the information includes a discovery signal periodicity, an offset and a secondary cell identifier, wherein the offset indicates a start point of the discovery signal based on a first sub-frame of a frame; determining a timing to measure the discovery signals from a secondary cell based on the periodicity, the offset, and a system frame number, SFN, of the primary cell; and measuring the discovery signals transmitted from the secondary cell based on the determined timing, wherein the discovery signal is a signal based on a channel-state information reference signal, CSI-RS, and wherein the information further includes information on CSI-RS. receiving, information on discovery signals from a primary cell, wherein the information includes a discovery signal periodicity, an offset and a secondary cell identifier, wherein the offset indicates a start point of the discovery signal based on a first sub-frame of a frame; determining a timing to measure the discovery signals from a secondary cell based on the periodicity, the offset, and a system frame number, SFN, of the primary cell; and measuring the discovery signals transmitted from the secondary cell based on the determined timing, wherein the discovery signal is a signal based on a channel-state information reference signal, CSI-RS, and wherein the information further includes information on CSI-RS.
Nivolumab for use in the treatment of a non-small cell lung cancer with ALK translocation, wherein nivolumab is administered in combination with ceritinib.
An implantable device for delivering cardiac function therapy to a patient, comprising: a plurality of pacing channels (30a-c, 31a-c, 32a-c, 33a-c, 34a-c) for delivering pacing pulses to multiple ventricular sites; a parasympathetic stimulation channel for stimulating parasympathetic nerves innervating the heart; a controller for controlling the delivery of pacing pulses to the multiple ventricular sites during a cardiac cycle in accordance with a programmed pacing mode, wherein the multi-site ventricular pacing therapy is delivered in accordance with a demand pacing mode which enforces a minimum ventricular rate; and wherein the controller is programmed to deliver multi-site ventricular pacing therapy in conjunction with parasympathetic stimulation to counteract a decreased cardiac output caused by said parasympathetic stimulation. a plurality of pacing channels (30a-c, 31a-c, 32a-c, 33a-c, 34a-c) for delivering pacing pulses to multiple ventricular sites; a parasympathetic stimulation channel for stimulating parasympathetic nerves innervating the heart; a controller for controlling the delivery of pacing pulses to the multiple ventricular sites during a cardiac cycle in accordance with a programmed pacing mode, wherein the multi-site ventricular pacing therapy is delivered in accordance with a demand pacing mode which enforces a minimum ventricular rate; and wherein the controller is programmed to deliver multi-site ventricular pacing therapy in conjunction with parasympathetic stimulation to counteract a decreased cardiac output caused by said parasympathetic stimulation.
A flexible cable and ferrule system for sternal reconstruction, the system comprising a fexible cable having first and second ends, wherein the first end of the flexible cable comprises a crimp fitting member, and wherein the crimp fitting member comprises a flattened disk-like crimp head comprising a diametrical hole sized so as to accommodate the flexible cable, characterized in that the system further comprises a ferrule securing the flexible cable in place, after the flexible cable is looped around a sternum and drawn through the hole to a predetermined tension.
A recording device for recording an image of an object, wherein the device comprises an optical axis and a concave mirror formed by rotating a curve about the optical axis, and whereas through the use of said concave mirror an image of an object is generated/can be generated through reflection, the object being located at or projected onto the optical axis near the focal point of the concave mirror, characterized in that a flat light scanner surface is disposed between the concave mirror and the object such that the light beams (15, 16) reflected by the concave mirror generate a two-dimensional projection of the object on the light scanner surface, wherein the light scanner surface comprises light receptors through which the incident light beams (15, 16) of the two-dimensional projection can be captured/are captured in relation to their frequency and/ or phase and/ or magnitude, the device further comprising means through which the captured two-dimensional projection is encoded/ can be encoded in an electronic file.
An array of micro devices, the array comprising: a source substrate having a process side; a sacrificial layer comprising sacrificial material on the process side of the source substrate; a plurality of releasable micro objects (106, 402, 1010) formed at least in part on the sacrificial layer; a plurality of anchor structures (108, 408) located on the process side of the source substrate, wherein the anchor structures remain rigidly attached to the source substrate in the absence of the sacrificial material; and a plurality of tethers (110, 404), wherein each tether of the plurality of tethers connects a releasable micro object (106, 402, 1010) of the plurality of releasable micro objects to one of the anchor structures, so that in the absence of the sacrificial material the releasable micro objects move with respect to the anchor structures and the tethers deform and are mechanically stressed, characterised in that each micro object (106, 402, 1010) of the plurality of micro objects is connected to a single anchor structure by a single tether (110, 404) located off-center on an anchor-facing edge of the releasable micro object. a source substrate having a process side; a sacrificial layer comprising sacrificial material on the process side of the source substrate; a plurality of releasable micro objects (106, 402, 1010) formed at least in part on the sacrificial layer; a plurality of anchor structures (108, 408) located on the process side of the source substrate, wherein the anchor structures remain rigidly attached to the source substrate in the absence of the sacrificial material; and a plurality of tethers (110, 404), wherein each tether of the plurality of tethers connects a releasable micro object (106, 402, 1010) of the plurality of releasable micro objects to one of the anchor structures, so that in the absence of the sacrificial material the releasable micro objects move with respect to the anchor structures and the tethers deform and are mechanically stressed, characterised in that each micro object (106, 402, 1010) of the plurality of micro objects is connected to a single anchor structure by a single tether (110, 404) located off-center on an anchor-facing edge of the releasable micro object.