mhurhangee/ep-ind-claims huggingface dataset:
Isolated nucleic acid encoding a leader, which is selected from the group consisting of a) a leader peptide with the amino acid sequence of SEQ ID 10 or a functional variant thereof with one or two point mutations, and b) a leader peptide with the amino acid sequence selected from the group consisting of SEQ ID 11, 12, 13 and 14. a) a leader peptide with the amino acid sequence of SEQ ID 10 or a functional variant thereof with one or two point mutations, and b) a leader peptide with the amino acid sequence selected from the group consisting of SEQ ID 11, 12, 13 and 14.
A method of diagnosing a microbial infection in a subject, the method comprising: (i) assaying a biological sample obtained from a subject for the presence of microbe-associated molecular patterns (MAMPs) with a pattern recognition receptor -based assay; (ii) comparing the detectable signal level of MAMPs obtained from (i) to a reference level; and (iii) identifying the subject to be likely infected with at least one microbe having a masking capsule (encapsulated) if the detectable signal level of MAMPs is higher than the reference level; or identifying the subject to be unlikely infected with microbes if the detectable signal level is not higher than the reference level; wherein the method comprises pre-treating the sample to lyse or kill the at least one encapsulated microbe before assaying with the PRR-based assay; wherein said pre-treatment disrupts the cell wall of the at least one encapsulated microbe; wherein said pre-treatment is physical, mechanical, chemical, radiation, biological, or any combinations thereof; and wherein the reference level corresponds to the level of MAMPs in the same sample without pre-treatment. (i) assaying a biological sample obtained from a subject for the presence of microbe-associated molecular patterns (MAMPs) with a pattern recognition receptor -based assay; (ii) comparing the detectable signal level of MAMPs obtained from (i) to a reference level; and (iii) identifying the subject to be likely infected with at least one microbe having a masking capsule (encapsulated) if the detectable signal level of MAMPs is higher than the reference level; or identifying the subject to be unlikely infected with microbes if the detectable signal level is not higher than the reference level; wherein the method comprises pre-treating the sample to lyse or kill the at least one encapsulated microbe before assaying with the PRR-based assay; wherein said pre-treatment disrupts the cell wall of the at least one encapsulated microbe; wherein said pre-treatment is physical, mechanical, chemical, radiation, biological, or any combinations thereof; and wherein the reference level corresponds to the level of MAMPs in the same sample without pre-treatment. wherein the method comprises pre-treating the sample to lyse or kill the at least one encapsulated microbe before assaying with the PRR-based assay; wherein said pre-treatment disrupts the cell wall of the at least one encapsulated microbe; wherein said pre-treatment is physical, mechanical, chemical, radiation, biological, or any combinations thereof; and wherein the reference level corresponds to the level of MAMPs in the same sample without pre-treatment.
A side conveyor (104, 106) for a draper header, the side conveyor (104, 106) comprising: an endless belt with a web having a width in a direction transverse to a direction of travel of the web ("B"), and having an upper, crop conveying surface that is generally planar over substantially its entire extent, the web comprising a forward edge portion; and a crop ramp comprising a plurality of crop ramp segments, wherein each of the plurality of crop ramp segments comprises a rear portion, wherein the rear portion has a trailing edge, wherein the rear portion covers the forward edge portion, wherein at least one elongate recess is formed on an undersurface of the rear portion and wherein the at least one elongate recess is disposed at an angle, characterized in that the web comprises a plurality of protrusions (300, 400, 500, 502, 504, 602, 606) fixed to and extending upward from the forward edge portion, that the longitudinal axis of the least one elongate recess extends in the direction of travel of the web ("B") and also rearward to convey crop particles trapped between the forward edge portion of the web and the undersurface toward a trailing edge of each of the plurality of crop ramp segments, the plurality of protrusions (300, 400, 500, 502, 504, 602, 606) disposed to engage the at least one elongate recess and sweep the crop particles along the at least one elongate recess and toward the trailing edge. an endless belt with a web having a width in a direction transverse to a direction of travel of the web ("B"), and having an upper, crop conveying surface that is generally planar over substantially its entire extent, the web comprising a forward edge portion; and a crop ramp comprising a plurality of crop ramp segments, wherein each of the plurality of crop ramp segments comprises a rear portion, wherein the rear portion has a trailing edge, wherein the rear portion covers the forward edge portion, wherein at least one elongate recess is formed on an undersurface of the rear portion and wherein the at least one elongate recess is disposed at an angle, characterized in that the web comprises a plurality of protrusions (300, 400, 500, 502, 504, 602, 606) fixed to and extending upward from the forward edge portion, that the longitudinal axis of the least one elongate recess extends in the direction of travel of the web ("B") and also rearward to convey crop particles trapped between the forward edge portion of the web and the undersurface toward a trailing edge of each of the plurality of crop ramp segments, the plurality of protrusions (300, 400, 500, 502, 504, 602, 606) disposed to engage the at least one elongate recess and sweep the crop particles along the at least one elongate recess and toward the trailing edge.
A plug connector for wiring, including an attachment plug and a plug receptacle, the plug connector comprising: a sound collector configured to collect an ambient sound to generate a sound signal in form of an electric signal; and a determination processor; wherein the plug connector is provided with, as a target sound, a plurality of types of target sounds, wherein the determination processor has a first mode and a second mode as operation modes, and is configured to: detect, in the first mode, a first target sound of the plurality of types of target sounds as a detection target based on the sound signal to determine whether or not an event associated with generation of the first target sound occurs, and detect, in the second mode, a second target sound of the plurality of types of target sounds as the detection target based on the sound signal to determine whether or not an event associated with generation of the second target sound occurs, wherein the type of the first target sound and the type of the second target sound are different from each other, characterized in that the determination processor is configured to not detect, in the first mode, the second target sound and to not detect, in the second mode, the first target sound. a sound collector configured to collect an ambient sound to generate a sound signal in form of an electric signal; and a determination processor; wherein the plug connector is provided with, as a target sound, a plurality of types of target sounds, wherein the determination processor has a first mode and a second mode as operation modes, and is configured to: detect, in the first mode, a first target sound of the plurality of types of target sounds as a detection target based on the sound signal to determine whether or not an event associated with generation of the first target sound occurs, and detect, in the second mode, a second target sound of the plurality of types of target sounds as the detection target based on the sound signal to determine whether or not an event associated with generation of the second target sound occurs, detect, in the first mode, a first target sound of the plurality of types of target sounds as a detection target based on the sound signal to determine whether or not an event associated with generation of the first target sound occurs, and detect, in the second mode, a second target sound of the plurality of types of target sounds as the detection target based on the sound signal to determine whether or not an event associated with generation of the second target sound occurs, wherein the type of the first target sound and the type of the second target sound are different from each other, characterized in that the determination processor is configured to not detect, in the first mode, the second target sound and to not detect, in the second mode, the first target sound.
An imaging system, comprising: a base; an imaging assembly, comprising: a first arm including a first arm first portion and a first arm second portion distal from the first arm first portion, the first arm pivotally mounted on the base at the first arm first portion on a first pivot mount, a second arm including a second arm first portion and a second arm second portion distal from the second arm first portion, the second arm pivotally mounted on the first arm second portion at the second arm first portion on a second pivot mount, and an imaging device mounted on the second arm second portion; characterized by a holder assembly, comprising: a base mount mounted on a platform coupled to the base, a strut coupled to the base mount, and a gripper coupled to the strut, the gripper configured to grip a part, wherein, the second arm is rotatable about the second pivot mount to rotate the imaging device about an axis of the system around the part such that the part is imaged from a plurality of angles by the imaging device. a base; an imaging assembly, comprising: a first arm including a first arm first portion and a first arm second portion distal from the first arm first portion, the first arm pivotally mounted on the base at the first arm first portion on a first pivot mount, a second arm including a second arm first portion and a second arm second portion distal from the second arm first portion, the second arm pivotally mounted on the first arm second portion at the second arm first portion on a second pivot mount, and an imaging device mounted on the second arm second portion; characterized by a first arm including a first arm first portion and a first arm second portion distal from the first arm first portion, the first arm pivotally mounted on the base at the first arm first portion on a first pivot mount, a second arm including a second arm first portion and a second arm second portion distal from the second arm first portion, the second arm pivotally mounted on the first arm second portion at the second arm first portion on a second pivot mount, and an imaging device mounted on the second arm second portion; characterized by a holder assembly, comprising: a base mount mounted on a platform coupled to the base, a strut coupled to the base mount, and a gripper coupled to the strut, the gripper configured to grip a part, a base mount mounted on a platform coupled to the base, a strut coupled to the base mount, and a gripper coupled to the strut, the gripper configured to grip a part, wherein, the second arm is rotatable about the second pivot mount to rotate the imaging device about an axis of the system around the part such that the part is imaged from a plurality of angles by the imaging device.
Holding device for a membrane for a medical application to the eye, comprising two rings (12, 14) being disposed concentrically with respect to each other, wherein a first ring, which is embodied as an inner ring of a receptacle, is received on the inside of a second ring which is configured as an outer ring, wherein said membrane can be disposed in the region of said receptacle such that it can be clamped circumferentially between the two rings and such that the common opening of the two rings (12, 14) is covered, wherein the two rings feature a common frusto-conical inner surface, the inner ring is largely dimensionally stable and the outer ring is elastic, wherein the outer ring encloses the inner ring under tension and the membrane can be held between the outer ring and the inner ring by means of said tension, characterized in that the outer ring features an essentially triangular base with a wedge-shaped recess forming the receptacle, wherein one side of the triangle, starting from one of the vertices thereof, is partially formed by one side of the wedge-shaped recess, and wherein one vertex forms a rounded edge in opposite angle to said side.
A method of preparing a single-serve container (100, 300) configured for receipt in a single-serve brewing machine for rapid extraction of cannabis using water, the method comprising: processing cannabis by pulverizing the cannabis and by heating the cannabis in an oven at a temperature of between 120 and 140 degrees Celsius for a time period in the range of 30 to 60 minutes to decarboxylate the cannabis; adding the processed cannabis to the single-serve container (100, 300); adding, to the single-serve container (100, 300), an amount of a lipid-rich food-based extraction agent, wherein the extraction agent is a powder and is solid at room temperature, and sealing the single-serve container (100, 300). processing cannabis by pulverizing the cannabis and by heating the cannabis in an oven at a temperature of between 120 and 140 degrees Celsius for a time period in the range of 30 to 60 minutes to decarboxylate the cannabis; adding the processed cannabis to the single-serve container (100, 300); adding, to the single-serve container (100, 300), an amount of a lipid-rich food-based extraction agent, wherein the extraction agent is a powder and is solid at room temperature, and sealing the single-serve container (100, 300).
An electrode comprising: a resin current collector containing a polymer material and a conductive filler; an active material layer disposed adjacent to the resin current collector; and a second concavoconvex shape that coincides with a first concavoconvex shape formed on a surface of the active material layer that is in contact with the resin current collector, the second concavoconvex shape being formed on a surface of the resin current collector that is in contact with the active material layer, wherein the active material layer is disposed between the resin current collector and an electrolyte layer, the active material layer comprises a plurality of active materials and a first conductive member continuously arranged from a surface on the resin current collector side to a surface on the electrolyte layer side and having higher electron conductivity than the active material, and in the second concavoconvex shape in the resin current collector, at least a part of a second conductive member that is in electrical contact with the conductive filler exists in the resin current collector beyond the surface of the resin current collector. a resin current collector containing a polymer material and a conductive filler; an active material layer disposed adjacent to the resin current collector; and a second concavoconvex shape that coincides with a first concavoconvex shape formed on a surface of the active material layer that is in contact with the resin current collector, the second concavoconvex shape being formed on a surface of the resin current collector that is in contact with the active material layer, wherein the active material layer is disposed between the resin current collector and an electrolyte layer, the active material layer comprises a plurality of active materials and a first conductive member continuously arranged from a surface on the resin current collector side to a surface on the electrolyte layer side and having higher electron conductivity than the active material, and in the second concavoconvex shape in the resin current collector, at least a part of a second conductive member that is in electrical contact with the conductive filler exists in the resin current collector beyond the surface of the resin current collector.
Field-effect transistor with local source-drain insulation, having a semiconductor substrate; a source depression and a drain depression, which are formed in a manner spaced apart from one another in the semiconductor substrate; a depression insulation layer, which is formed at least in a bottom region of the source depression and of the drain depression; an electrically conductive filling layer, which is formed for realizing source and drain regions (S, D) and for filling the source and drain depressions (SV, DV) at the surface of the depression insulation layer; a gate dielectric, which is formed at the substrate surface between the source and drain depressions (SV, DV); and a gate layer, which is formed at the surface of the gate dielectric, the source and drain depressions (SV, DV) having, in an upper region, a widening with a predetermined depth for realizing defined channel connection regions, the depression insulation layer furthermore having a depression sidewall insulation layer, which is formed in the sidewall region of the source and drain depressions (SV, DV) and which extends into a region below the gate dielectric but does not touch the gate dielectric.
A chin ring heat shield for a wheel assembly arranged to provide a shield between convection and radiation heat from braking components (16, 18)and a wheel of the wheel assembly, the chin ring heat shield comprising a first, radially extending, flat portion extending from a first chin ring end and a second, concave portion extending generally axially away from the first portion to a second chin ring end,and characterised in that the chin ring heat shield comprises an intermediate, straight portion extending in an axial direction from the first, radially extending, flat portion and from which the second, concave portion extends, and wherein the intermediate portion is at an angle of substantially 90 degrees to the first radially extending flat portion.
A method comprising: hydrocracking a polynucleararomatic hydrocarbon feed in the presence of hydrogen and a base metal catalyst at 380°C to 430°C, 2500 psig (17.34 MPa) or greater, and 0.1 hr -1 to 5 hr -1 liquid hourly space velocity (LSHV), wherein the weight ratio of PNA feed to hydrogen is 30:1 to 10:1, wherein the PNA feed comprises 25 wt% or less of hydrocarbons having a boiling point of 700°F (371°C) or less and 2 wt% or greater sulfur and having an aromatic content of 50 wt% or greater to form a first product; separating the first product into an overheads stream and a 950+°F (510°C) bottoms stream, wherein the overheads stream comprises 50 wt% or greater of the hydrocarbons having a boiling point of 700°F (371°C) or less and having an aromatic content of 20 wt% or less; distilling the overheads stream into a 700+°F (371+°C) boiling point stream having less than 15 ppm sulfur and one or more fractions selected from the group consisting of: a C 4- paraffin stream comprising less than 15 ppm sulfur, a naphtha fraction having less than 15 ppm sulfur, and a distillate fraction having less than 15 ppm sulfur; hydrocracking the 700+°F (371+°C) boiling point stream in the presence of hydrogen and a noble metal catalyst to form a second product; and recycling the second product to mix the second product and the overheads before distillation. hydrocracking a polynucleararomatic hydrocarbon feed in the presence of hydrogen and a base metal catalyst at 380°C to 430°C, 2500 psig (17.34 MPa) or greater, and 0.1 hr -1 to 5 hr -1 liquid hourly space velocity (LSHV), wherein the weight ratio of PNA feed to hydrogen is 30:1 to 10:1, wherein the PNA feed comprises 25 wt% or less of hydrocarbons having a boiling point of 700°F (371°C) or less and 2 wt% or greater sulfur and having an aromatic content of 50 wt% or greater to form a first product; separating the first product into an overheads stream and a 950+°F (510°C) bottoms stream, wherein the overheads stream comprises 50 wt% or greater of the hydrocarbons having a boiling point of 700°F (371°C) or less and having an aromatic content of 20 wt% or less; distilling the overheads stream into a 700+°F (371+°C) boiling point stream having less than 15 ppm sulfur and one or more fractions selected from the group consisting of: a C 4- paraffin stream comprising less than 15 ppm sulfur, a naphtha fraction having less than 15 ppm sulfur, and a distillate fraction having less than 15 ppm sulfur; hydrocracking the 700+°F (371+°C) boiling point stream in the presence of hydrogen and a noble metal catalyst to form a second product; and recycling the second product to mix the second product and the overheads before distillation.
A flexible container for an injection device, comprising: - a flexible bag having an interior volume to be filled with a liquid medicament, - an outlet located at a first end of the bag, - a contraction member connected to the bag to displace a second end of the bag, located opposite to the first end, towards the first end, - a sidewall located between the first end and the second end, and wherein at least one of the first end and the second end is flexible, characterized in that - the contraction member comprises a helically shaped tension spring having at least two windings extending around the bag and wherein the contraction member is connected to the sidewall or to the mutually oppositely located first and second ends (13, 15) of the flexible bag. - a flexible bag having an interior volume to be filled with a liquid medicament, - an outlet located at a first end of the bag, - a contraction member connected to the bag to displace a second end of the bag, located opposite to the first end, towards the first end, - a sidewall located between the first end and the second end, and wherein at least one of the first end and the second end is flexible, characterized in that - the contraction member comprises a helically shaped tension spring having at least two windings extending around the bag and wherein the contraction member is connected to the sidewall or to the mutually oppositely located first and second ends (13, 15) of the flexible bag.