A method for displaying virtual slide images using a viewer application on a display device (143, 147) of a virtual slide viewing device (142, 146) for a pathologist making a diagnosis, comprising: automatically displaying images of a plurality of slides (310, 312, 314, 316) in a first region of the display device at a first magnification upon opening a case using the viewer application, wherein said first region is continuous and said plurality of slides comprise all of the slides of the case currently being reviewed by the pathologist, wherein the first region has its own first coordinate system and each image of the plurality of slides has its own internal coordinate system and the image data for the plurality of slides has a position within the coordinate system of an individual slide and each slide image has a position within the first coordinate system, _and wherein each slide includes a different section of tissue; displaying an image (318, 320, 322, 324) of at least a part of at least one of the plurality of slides in a second region of the display device at a second magnification, wherein said second magnification is greater than said first magnification; receiving user input to the virtual slide viewing device by user interaction with the first coordinate system of the first region to view any different region of any of the plurality of slides in the second region of the display device; and changing at least the image displayed in the second region of the display device responsive to said user interaction with the first region to display the different region of any of the plurality of slides in the second region of the display device, and wherein said images of the plurality of slides are always displayed in the first region during the method. automatically displaying images of a plurality of slides (310, 312, 314, 316) in a first region of the display device at a first magnification upon opening a case using the viewer application, wherein said first region is continuous and said plurality of slides comprise all of the slides of the case currently being reviewed by the pathologist, wherein the first region has its own first coordinate system and each image of the plurality of slides has its own internal coordinate system and the image data for the plurality of slides has a position within the coordinate system of an individual slide and each slide image has a position within the first coordinate system, _and wherein each slide includes a different section of tissue; displaying an image (318, 320, 322, 324) of at least a part of at least one of the plurality of slides in a second region of the display device at a second magnification, wherein said second magnification is greater than said first magnification; receiving user input to the virtual slide viewing device by user interaction with the first coordinate system of the first region to view any different region of any of the plurality of slides in the second region of the display device; and changing at least the image displayed in the second region of the display device responsive to said user interaction with the first region to display the different region of any of the plurality of slides in the second region of the display device, and wherein said images of the plurality of slides are always displayed in the first region during the method.