A compound of Formula I or a pharmaceutically acceptable salt thereof, wherein: R 1 is ―H, C 1-4 alkyl, or C 1-4 haloalkyl; R 2 is C 1-6 alkyl or C 1-6 haloalkyl; Q is CR 4; R 3 and R 4 are taken together to form: or phenyl optionally substituted with 1 to 3 R 5, wherein each R 5, R 6, and R 7 is optionally present; each R 5 is independently halogen, -OH, -NH 2, -CN, C 1-4 alkyl optionally substituted with 1 to 3 R Z, C 1-4 haloalkyl, C 1-4 alkoxy, -C OH, -C C 1-4 alkyl, -C OC 1-4 alkyl, -C NH 2, -C NH(C 1-4 alkyl), -C N(C 1-4 alkyl) 2, -N C C 1-4 alkyl, -S 2 C 1-4 alkyl, or 5 to 6 membered heteroaryl having 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur optionally substituted with 1 to 3 R Z; each R 6 is independently halogen, -OH, -NH 2, -CN, C 1-4 alkyl optionally substituted with 1 phenyl optionally substituted with 1 to 3 R Z; C 1-4 haloalkyl, C 1-4 alkoxy, -S 2 C 1-4 alkyl; 5 to 6 membered heterocyclyl having 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur optionally substituted with 1 to 3 R Z; phenyl optionally substituted with 1 to 3 R Z; or 5 to 6 membered heteroaryl having 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur optionally substituted with 1 to 3 R Z; R 7 is halogen, -OH, C 1-4 alkyl, C 1-4 alkoxy, or -C R 8; each R 8 is independently C 1-4 alkyl optionally substituted with -CN or -NH 2; C 1-4 haloalkyl; C 5-6 cycloalkyl, 5 to 6 membered heterocyclyl having 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur optionally substituted with 1 to 3 R Z; or 5 to 10 membered heteroaryl having 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur optionally substituted with 1 to 3 R Z; and each R Z is independently -NH 2, C 1-4 alkyl, halogen, -CN, -OC 1-4 alkyl, C 1-4 haloalkyl, or -C NH 2. R 1 is ―H, C 1-4 alkyl, or C 1-4 haloalkyl; R 2 is C 1-6 alkyl or C 1-6 haloalkyl; Q is CR 4; R 3 and R 4 are taken together to form: or phenyl optionally substituted with 1 to 3 R 5, wherein each R 5, R 6, and R 7 is optionally present; each R 5 is independently halogen, -OH, -NH 2, -CN, C 1-4 alkyl optionally substituted with 1 to 3 R Z, C 1-4 haloalkyl, C 1-4 alkoxy, -C OH, -C C 1-4 alkyl, -C OC 1-4 alkyl, -C NH 2, -C NH(C 1-4 alkyl), -C N(C 1-4 alkyl) 2, -N C C 1-4 alkyl, -S 2 C 1-4 alkyl, or 5 to 6 membered heteroaryl having 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur optionally substituted with 1 to 3 R Z; each R 6 is independently halogen, -OH, -NH 2, -CN, C 1-4 alkyl optionally substituted with 1 phenyl optionally substituted with 1 to 3 R Z; C 1-4 haloalkyl, C 1-4 alkoxy, -S 2 C 1-4 alkyl; 5 to 6 membered heterocyclyl having 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur optionally substituted with 1 to 3 R Z; phenyl optionally substituted with 1 to 3 R Z; or 5 to 6 membered heteroaryl having 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur optionally substituted with 1 to 3 R Z; R 7 is halogen, -OH, C 1-4 alkyl, C 1-4 alkoxy, or -C R 8; each R 8 is independently C 1-4 alkyl optionally substituted with -CN or -NH 2; C 1-4 haloalkyl; C 5-6 cycloalkyl, 5 to 6 membered heterocyclyl having 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur optionally substituted with 1 to 3 R Z; or 5 to 10 membered heteroaryl having 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur optionally substituted with 1 to 3 R Z; and each R 5 is independently halogen, -OH, -NH 2, -CN, C 1-4 alkyl optionally substituted with 1 to 3 R Z, C 1-4 haloalkyl, C 1-4 alkoxy, -C OH, -C C 1-4 alkyl, -C OC 1-4 alkyl, -C NH 2, -C NH(C 1-4 alkyl), -C N(C 1-4 alkyl) 2, -N C C 1-4 alkyl, -S 2 C 1-4 alkyl, or 5 to 6 membered heteroaryl having 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur optionally substituted with 1 to 3 R Z; each R 6 is independently halogen, -OH, -NH 2, -CN, C 1-4 alkyl optionally substituted with 1 phenyl optionally substituted with 1 to 3 R Z; C 1-4 haloalkyl, C 1-4 alkoxy, -S 2 C 1-4 alkyl; 5 to 6 membered heterocyclyl having 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur optionally substituted with 1 to 3 R Z; phenyl optionally substituted with 1 to 3 R Z; or 5 to 6 membered heteroaryl having 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur optionally substituted with 1 to 3 R Z; R 7 is halogen, -OH, C 1-4 alkyl, C 1-4 alkoxy, or -C R 8; each R 8 is independently C 1-4 alkyl optionally substituted with -CN or -NH 2; C 1-4 haloalkyl; C 5-6 cycloalkyl, 5 to 6 membered heterocyclyl having 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur optionally substituted with 1 to 3 R Z; or 5 to 10 membered heteroaryl having 1 to 3 heteroatoms selected from oxygen, nitrogen, and sulfur optionally substituted with 1 to 3 R Z; and each R Z is independently -NH 2, C 1-4 alkyl, halogen, -CN, -OC 1-4 alkyl, C 1-4 haloalkyl, or -C NH 2.