A compound selected from VT-03-00045: 6-methoxy-4-(2-(4-(4-nitrobenzylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile; VT-03-00046: 4-(2-(4-(4-hydroxy-3-methoxybenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile; VT-03-00048: 4-(2-(4-(4-fluoro-3-nitrobenzylamino)-piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile; VT-03-00049: 6-methoxy-4-(2-(4-(3-nitrobenzylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile; VT-03-00050: 4-(2-(4-(2-fluoro-5-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile; VT-03-00051: 6-methoxy-4-(2-(4-((5-nitrofuran-2-yl)methylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile; VT-03-00052: 6-methoxy-4-(2-(4-((5-nitrothiophen-2-yl)methylamino)-piperidin-1-yl)ethyl)quinoline-3-carbonitrile; VT-03-00053: 6-methoxy-4-(2-(4-((5-nitrothiophen-3-yl)methylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile; VT-03-00054: 4-(2-(4-(3-fluoro-4-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile; VT-03-00055: N-(1-(2-(3-cyano-6-methoxyquinolin-4-yl)ethyl)piperidin-4-yl)-3-fluoro-4-nitrobenzamide; VT-03-00058: 4-(2-(4-(4-chloro-3-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile; VT-03-00059: 4-(2-(4-(2-hydroxy-5-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile; VT-03-00060: 4-(2-(4-(4-hydroxy-3-methoxy-5-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile; VT-03-00061: 6-methoxy-4-(2-(4-(4-methyl-3-nitrobenzylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile; VT-03-00063: 6-methoxy-4-(2-(4-(4-methoxy-3-nitrobenzylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile; VT-03-00064: 4-(2-(4-(4-(dimethylamino)-3-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile; VT-03-00069: 6-methoxy-4-(2-((1R,5S)-3-(4-methyl-3-nitrobenzylamino)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)quinoline-3-carbonitrile; VT-03-00071: 4-(2-((1R,5S)-3-(2,5-dimethyl-3-nitrobenzylamino)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-6-methoxyquinoline-3-carbonitrile; VT-03-00072: 6-methoxy-4-(2-((1R,5S)-3-((5-nitrothiophen-2-yl)methylamino)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)quinoline-3-carbonitrile; VT-03-00074: 4-(2-(4-(2,5-dimethyl-3-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile; VT-03-00075: 4-(2-(4-(2,4-dimethyl-5-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile; VT-03-00076:4- (2-(4-(4-ethyl-3-nitrobenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile; VT-03-00078: 6-methoxy-4-(2-(4-((5-nitro-1H-imidazol-2-yl)methylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile; VT-03-00079: 6-methoxy-4-(2-(4-((4-nitropyridin-2-yl)methylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile; VT-03-00080: 6-methoxy-4-(2-(4-((2-nitrothiazol-4-yl)methylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile; VT-03-00081: 6-methoxy-4-(2-(4-((5-nitropyridin-2-yl)methylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile; VT-03-00083: 1-(2-(3-cyano-6-methoxyquinolin-4-yl)ethyl)-4-(4-methyl-3-nitrobenzylamino)piperidine-4-carboxamide; VT-03-00084: 6-methoxy-4-(2-(3-((4-methyl-3-nitrobenzylamino)methyl)azetidin-1-yl)ethyl)quinoline-3-carbonitrile; VT-03-00085: 6-methoxy-4-(2-(6-(4-methyl-3-nitrobenzylamino)-2-azaspiro[3.3]heptan-2-yl)ethyl)quinoline-3-carbonitrile; VT-03-00086: -6-methoxy-4-(2-(2-((4-methyl-3-nitrobenzylamino)methyl)pyrrolidin-1-yl)ethyl)quinoline-3-carbonitrile; VT-03-00087: 6-methoxy-4-(2-(9-(4-methyl-3-nitrobenzylamino)-2-oxa-6-azaspiro[3.5]nonan-6-yl)ethyl)quinoline-3-carbonitrile; VT-03-00088: 6-methoxy-4-(2-(4-((6-methylpyridin-3-yl)methylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile; VT-03-00089: 4-(2-(4-(2,3-difluoro-4-methylbenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile; VT-03-00090: 6-methoxy-4-(2-(4-(4-methyl-3-(trifluoromethyl)benzylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile; VT-03-00092: 4-(2-(4-(3-acetyl-4-methylbenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile; VT-03-00093: 4-(2-(4-(3-cyano-4-methylbenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile; VT-03-00094: 6-methoxy-4-(2-(4-(4-methyl-3-(1,1,1-trifluoropropan-2-yl)benzylamino)piperidin-1-yl)ethyl)quinoline-3-carbonitrile; or VT-03-00095: 4-(2-(4-(3-fluoro-4-methylbenzylamino)piperidin-1-yl)ethyl)-6-methoxyquinoline-3-carbonitrile.