mhurhangee/ep-ind-claims huggingface dataset:
Method for screening the binding properties of constituent peptides of MHC molecules, said method comprising the steps of: (a) providing in solution MHC molecules or their constituent peptides for a set of MHC molecules, which set includes a plurality of subsets of MHC molecules, wherein the MHC molecules of each subset differ from MHC molecules of at least one other subset in at least one constituent peptide selected from the group consisting of a putative MHC binding peptide, an MHC alpha chain and an MHC beta chain, and loading said MHC molecules with an MHC binding peptide by (i) refolding of the MHC alpha chain and beta chain peptides in presence of said MHC binding peptide or (ii) by peptide exchange or loading with an unlabelled MHC binding peptide in the absence of any labelled MHC binding peptide, (b) taking of at least one sample from each subset, and (c) determining loading efficiency for the sample of step (b), wherein said loading efficiency is determined by measuring the proportion of loaded MHC molecules to unloaded MHC molecules, wherein said MHC molecules are MHC oligomers and wherein oligomerisation occurs before step b) such as after step a) or in parallel to loading by refolding in step a). (a) providing in solution MHC molecules or their constituent peptides for a set of MHC molecules, which set includes a plurality of subsets of MHC molecules, wherein the MHC molecules of each subset differ from MHC molecules of at least one other subset in at least one constituent peptide selected from the group consisting of a putative MHC binding peptide, an MHC alpha chain and an MHC beta chain, and loading said MHC molecules with an MHC binding peptide by (i) refolding of the MHC alpha chain and beta chain peptides in presence of said MHC binding peptide or (ii) by peptide exchange or loading with an unlabelled MHC binding peptide in the absence of any labelled MHC binding peptide, (i) refolding of the MHC alpha chain and beta chain peptides in presence of said MHC binding peptide or (ii) by peptide exchange or loading with an unlabelled MHC binding peptide in the absence of any labelled MHC binding peptide, (b) taking of at least one sample from each subset, and (c) determining loading efficiency for the sample of step (b), wherein said loading efficiency is determined by measuring the proportion of loaded MHC molecules to unloaded MHC molecules,
Coating system for producing a highly scratch-resistant layered composite comprising a primer composition and a surface composition, characterized in that the primer composition comprises a1) polyalkyl methacrylate, a2) polysiloxane, and a3) organic solvent, and in that the surface composition comprises b1) colloidal silica, b2) methyltrimethoxysilane and/or methyltriethoxysilane, b3) methyltriacetoxysilane, and b4) organic solvent, preferably n-butanol and/or isopropanol. a1) polyalkyl methacrylate, a2) polysiloxane, and a3) organic solvent, b1) colloidal silica, b2) methyltrimethoxysilane and/or methyltriethoxysilane, b3) methyltriacetoxysilane, and b4) organic solvent, preferably n-butanol and/or isopropanol.
A container with a handle, wherein the container comprises: - a lower base (2.1), and - an upper base (2.2) from which there emerges a neck (2.3) with an opening (2.4) for accessing the inside of the container; wherein the handle is for a stackable container that can be vertically stacked and wherein the handle comprises: - a fixing ring (1.1) adapted for being coupled to the neck (2.3) of the container; - a gripping element (1.3); and - an attachment section (1.2) between the gripping element (1.3) and the fixing ring (1.1); wherein: - the lower base (2.1) is configured for being supported on the upper base (2.2) of the container arranged immediately thereunder when it is stacked in a stack in the operative mode, - the lower base (2.1) has a cavity (2.1.1) for housing the neck (2.3) and the opening (2.4) of the container arranged immediately thereunder when it is stacked in a stack in the operative mode, - the fixing ring (1.1) of the handle is fixed to the neck (2.3) of the container characterized in that - the attachment section (1.2) of the handle comprises a sheet-like portion (1.2.1) configured for being arranged between the upper base (2.2) of the container on which the fixing ring (1.1) is fixed and the lower base (2.1) of the upper stacked container when they are stacked in the operative mode, and - the gripping element (1.3) is spaced from the support area between the upper base (2.2) and the lower base (2.1) of two consecutively stacked containers in order to leave the handle accessible for the user after stacking. - a lower base (2.1), and - an upper base (2.2) from which there emerges a neck (2.3) with an opening (2.4) for accessing the inside of the container; - a fixing ring (1.1) adapted for being coupled to the neck (2.3) of the container; - a gripping element (1.3); and - an attachment section (1.2) between the gripping element (1.3) and the fixing ring (1.1); - the lower base (2.1) is configured for being supported on the upper base (2.2) of the container arranged immediately thereunder when it is stacked in a stack in the operative mode, - the lower base (2.1) has a cavity (2.1.1) for housing the neck (2.3) and the opening (2.4) of the container arranged immediately thereunder when it is stacked in a stack in the operative mode, - the fixing ring (1.1) of the handle is fixed to the neck (2.3) of the container characterized in that - the attachment section (1.2) of the handle comprises a sheet-like portion (1.2.1) configured for being arranged between the upper base (2.2) of the container on which the fixing ring (1.1) is fixed and the lower base (2.1) of the upper stacked container when they are stacked in the operative mode, and - the gripping element (1.3) is spaced from the support area between the upper base (2.2) and the lower base (2.1) of two consecutively stacked containers in order to leave the handle accessible for the user after stacking.
A lift-truck comprising: - a load engagement means arranged to be moved by a lifting/lowering unit; - a support means extending from the load engagement means; - a distance sensor directed towards the load engagement means and configured to measure the distance to a surface (4, 50) on the load engagement means; - a control unit connected to an operator interface and to the lifting/lowering unit and to the distance sensor, characterized in that; - the distance sensor is attached to the support means at a fixed distance above the load engagement means, wherein - the control unit is configured to receive a start signal from the operator interface and in response thereto performing a height adjustment cycle of the load engagement means comprising; - determining a default distance (D 0) to the surface (4, 60) on the load engagement means; - determining the present distance to the surface (4, 60) on the load engagement means; - comparing the default distance (D 0) and the present distance; - moving the load engagement means a distance when a difference (D delta) between the default distance (D 0) and the present distance is determined, wherein the distance depends on the difference (D delta). - a load engagement means arranged to be moved by a lifting/lowering unit; - a support means extending from the load engagement means; - a distance sensor directed towards the load engagement means and configured to measure the distance to a surface (4, 50) on the load engagement means; - a control unit connected to an operator interface and to the lifting/lowering unit and to the distance sensor, characterized in that; - the distance sensor is attached to the support means at a fixed distance above the load engagement means, wherein - the control unit is configured to receive a start signal from the operator interface and in response thereto performing a height adjustment cycle of the load engagement means comprising; - determining a default distance (D 0) to the surface (4, 60) on the load engagement means; - determining the present distance to the surface (4, 60) on the load engagement means; - comparing the default distance (D 0) and the present distance; - moving the load engagement means a distance when a difference (D delta) between the default distance (D 0) and the present distance is determined, wherein the distance depends on the difference (D delta).
A photomultiplier comprising: an enclosure (2, 3, 4) having an inside kept in a vacuum state, said enclosure whose at least a part is constructed by a glass substrate having a flat part; a photocathode, accommodated in said enclosure, emitting photoelectrons to the inside of said enclosure in response to light captured through said enclosure; an electron multiplier section, arranged on a predetermined area of the flat part in said glass substrate, for multiplying in a cascading manner the photoelectrons emitted from said photocathode; and an anode, arranged on an area excluding the area where said electron multiplier section is arranged on the flat part in said glass substrate, for taking out electrons having arrived thereat among electrons multiplied in a cascading manner in said electron multiplier section as a signal, wherein; said enclosure comprises a lower frame comprised of said glass substrate; an upper frame opposing said lower frame; and a side wall frame, provided between said upper frame and said lower frame, having a form surrounding said electron multiplier section and said anode, and said electron multiplier section, said anode and said side wall frame are fixed to the flat part in said glass substrate, characterized in that said electron multiplier section, said anode and said side wall frame are formed from a single silicon substrate, an enclosure (2, 3, 4) having an inside kept in a vacuum state, said enclosure whose at least a part is constructed by a glass substrate having a flat part; a photocathode, accommodated in said enclosure, emitting photoelectrons to the inside of said enclosure in response to light captured through said enclosure; an electron multiplier section, arranged on a predetermined area of the flat part in said glass substrate, for multiplying in a cascading manner the photoelectrons emitted from said photocathode; and an anode, arranged on an area excluding the area where said electron multiplier section is arranged on the flat part in said glass substrate, for taking out electrons having arrived thereat among electrons multiplied in a cascading manner in said electron multiplier section as a signal, wherein; said enclosure comprises a lower frame comprised of said glass substrate; an upper frame opposing said lower frame; and a side wall frame, provided between said upper frame and said lower frame, having a form surrounding said electron multiplier section and said anode, and said electron multiplier section, said anode and said side wall frame are fixed to the flat part in said glass substrate, characterized in that said electron multiplier section, said anode and said side wall frame are formed from a single silicon substrate,
A payload of a measurement satellite of a system for locating a terrestrial transmitter of a target signal that is received by a main satellite in an Earth orbit over an uplink of said main satellite, said measurement satellite being intended to be placed in a traveling Earth orbit intercepting a downlink of said main satellite, said payload including a direct reception module that is adapted to measure said target signal received directly from the terrestrial transmitter, characterized in that said payload further includes an indirect reception module that is adapted to measure the target signal retransmitted by the main satellite over the downlink of said main satellite, and a transfer module that is adapted to transmit, to a ground station of the locating system: - a group of signals, referred to as homologous signals, that are measured by the direct reception module and the indirect reception module and that correspond to the target signal received from the terrestrial transmitter and from the main satellite, respectively; and/or - data that are determined on the basis of said homologous signals. - a group of signals, referred to as homologous signals, that are measured by the direct reception module and the indirect reception module and that correspond to the target signal received from the terrestrial transmitter and from the main satellite, respectively; and/or - data that are determined on the basis of said homologous signals.
A polymer composition comprising a random copolymer, wherein the random copolymer is produced with a metallocene catalyst, and a radiation additive, wherein the random copolymer comprises propylene and less than 2 wt.% ethylene and exhibits a melt flow rate of from 30 to 100 dg/min., the polymer composition exhibits a flexural modulus of from 1100 MPa to 1380 MPa (160 kpsi to 200 kpsi) and the polymer composition contains 0.10 wt% to 0.25 wt% of clarifier which is a sorbitol derivative, wherein a polymer article produced from the polymer composition exhibits low plate out, a haze at 0.508 mm (20 mils) of no greater than 15%, radiation stability and autoclavability.
An elongate medical appliance comprising a coating, wherein the elongate medical appliance comprises a wire, a hypotube, a guidewire, a mandrel, or a stylet, and wherein the elongate medical appliance comprises a metal or a metal alloy substrate; and wherein the coating is disposed concentrically around the elongate medical appliance, the coating comprising: a first layer comprising a polyethersulfone, the first layer being adhered to a surface of the elongate medical appliance; a second layer comprising a polyethersulfone, the second layer being disposed on the first layer; a third layer comprising a polymer blend comprising a polyethersulfone and a polyimide, the third layer being disposed on the second layer; and a fourth layer comprising a polymer blend comprising a polyethersulfone, a fluoropolymer, and a polyimide, the fourth layer being disposed on the third layer. a first layer comprising a polyethersulfone, the first layer being adhered to a surface of the elongate medical appliance; a second layer comprising a polyethersulfone, the second layer being disposed on the first layer; a third layer comprising a polymer blend comprising a polyethersulfone and a polyimide, the third layer being disposed on the second layer; and a fourth layer comprising a polymer blend comprising a polyethersulfone, a fluoropolymer, and a polyimide, the fourth layer being disposed on the third layer.
An automatic analysis device comprising: a measurement mechanism that has at least one light measuring unit in which a reaction container into which a specimen is dispensed is erected, a light source which is configured to irradiate the reaction container with light, and at least one detection unit which is configured to detect scattered light from the specimen in the reaction container; an amplification circuit unit that has an adder/subtracter which is configured to add or subtract a correction signal to/from a first measurement signal from the detection unit and an amplification circuit which is configured to amplify an output signal from the adder/subtracter with a fixed amplification rate and to output the amplified output signal as a second measurement signal; an arithmetic operation unit that is configured to calculate the correction signal based on a difference between a signal level of the second measurement signal and a target value thereof and to execute an analysis operation based on the second measurement signal after the correction by the correction signal; and a control unit that is configured to control operations of the measurement mechanism, the amplification circuit unit, and the arithmetic operation unit; characterized in that the arithmetic operation unit is configured to calculate a degree of an interference substance contained in the specimen based on the correction signal and based on a predetermined relationship between the degree of an interference substance and the correction signal. a measurement mechanism that has at least one light measuring unit in which a reaction container into which a specimen is dispensed is erected, a light source which is configured to irradiate the reaction container with light, and at least one detection unit which is configured to detect scattered light from the specimen in the reaction container; an amplification circuit unit that has an adder/subtracter which is configured to add or subtract a correction signal to/from a first measurement signal from the detection unit and an amplification circuit which is configured to amplify an output signal from the adder/subtracter with a fixed amplification rate and to output the amplified output signal as a second measurement signal; an arithmetic operation unit that is configured to calculate the correction signal based on a difference between a signal level of the second measurement signal and a target value thereof and to execute an analysis operation based on the second measurement signal after the correction by the correction signal; and a control unit that is configured to control operations of the measurement mechanism, the amplification circuit unit, and the arithmetic operation unit; characterized in that the arithmetic operation unit is configured to calculate a degree of an interference substance contained in the specimen based on the correction signal and based on a predetermined relationship between the degree of an interference substance and the correction signal.
A stabiliser for an organic polymer mixture, comprising one or more compounds from group (a) and one or more compounds from group (c) wherein (a) and (c) are as follows; (a) Antioxidant L; (CAS68610-51-5); (c) Antioxidant 1520, (CAS110553-27-0); wherein the ratio by weight of (a):(c) is in the range 4:1 to 1:1. (a) Antioxidant L; (CAS68610-51-5); (c) Antioxidant 1520, (CAS110553-27-0);
An overvoltage protection device for electrical terminal devices which, in addition to an at least single-phase low-voltage supply system connection, have at least one control signal connection (Lst) for switching a lamp arrangement in a street lighting system on and off, wherein a change in the operating state of the respective terminal device or of a consumer can be specified by means of the control signal connection (Lst), consisting of an arrangement of varistors which are each assigned a thermal disconnecting device and an optical function display, and having at least one gas discharge tube which is connected between a neutral conductor and a protective earth conductor, wherein furthermore a first varistor with a thermal disconnecting device is provided between the power supply system connection and a neutral conductor and a second varistor with a thermal disconnecting device is provided between the control signal connection (Lst) and the neutral conductor, wherein the overvoltage protection device (KÜG) is adapted to be arranged in the immediate vicinity of the electrical terminal device or consumer in a terminal box which is located within a conductive pole, wherein the optical function displays are provided for a separate signaling of overvoltage events of the power supply system connection and of the control signal connection (Lst), wherein in the case of a power supply from a TNC power system with a PEN conductor, which is at the same time a protective earth conductor and a neutral conductor, the gas discharge tube is connected between the PEN conductor and the conductive pole to form a potential equalization.
9-[(2,2-dimethyl-propyl amino)-methyl]-minocycline or a salt thereof for use in a method of treating Community-Acquired Bacterial Pneumonia (CABP) in a subject in need of treatment thereof, wherein the method comprises administering to said subject 9-[(2,2-dimethyl-propyl amino)-methyl]-minocycline or a salt thereof according to the following dosing regimen: three intravenous doses of about 100 mg each, administered 12 hours apart, followed by, optionally, one or more intravenous doses of about 100 mg each, each administered 24 hours following the immediate preceding intravenous dose, followed by, optionally, one oral dose of about 300 mg, administered in the morning and 12-24 hrs after the immediate preceding intravenous dose, followed by, optionally, one or more oral doses of about 300 mg each, each administered 24 hours following the immediate preceding oral dose, such that said subject is treated. three intravenous doses of about 100 mg each, administered 12 hours apart, followed by, optionally, one or more intravenous doses of about 100 mg each, each administered 24 hours following the immediate preceding intravenous dose, followed by, optionally, one oral dose of about 300 mg, administered in the morning and 12-24 hrs after the immediate preceding intravenous dose, followed by, optionally, one or more oral doses of about 300 mg each, each administered 24 hours following the immediate preceding oral dose,
A signal transmission method, comprising: determining a codebook C, wherein the codebook C is a set of matrices W; determining a matrix set Ω = ∈ C from the codebook C; generating one or more layers of signals, beamforming the signals with a matrix in the matrix set Ω, and cyclically mapping the matrixes in the matrix set Ω to different locations of transmission resources; and transmitting the beamformed signals at the different locations of the transmission resources; wherein each matrix W is generated by transforming a phase φ of at least one Discrete Fourier Transform DFT vector V; a set of DFT vectors corresponding to the matrices W in the matrix set Ω constitutes a group of adjacent DFT vectors V = { V 1,V 2,....V N}; a set of phases corresponding to the matrices W in the matrix set Ω constitutes a set of adjacent phases Θ = { φ 1, φ 2,... φ K}; characterized in that the DFT vectors corresponding to the matrices W mapped to adjacent transmission resources are discontinuous in V = { V 1, V 2,,,.V N}, or the phases φ corresponding to the matrices W mapped to adjacent transmission resources are discontinuous in Θ = { φ 1, φ 2,... φ K}. determining a codebook C, wherein the codebook C is a set of matrices W; determining a matrix set Ω = ∈ C from the codebook C; generating one or more layers of signals, beamforming the signals with a matrix in the matrix set Ω, and cyclically mapping the matrixes in the matrix set Ω to different locations of transmission resources; and transmitting the beamformed signals at the different locations of the transmission resources; wherein each matrix W is generated by transforming a phase φ of at least one Discrete Fourier Transform DFT vector V; a set of DFT vectors corresponding to the matrices W in the matrix set Ω constitutes a group of adjacent DFT vectors V = { V 1,V 2,....V N}; a set of phases corresponding to the matrices W in the matrix set Ω constitutes a set of adjacent phases Θ = { φ 1, φ 2,... φ K}; characterized in that the DFT vectors corresponding to the matrices W mapped to adjacent transmission resources are discontinuous in V = { V 1, V 2,,,.V N}, or the phases φ corresponding to the matrices W mapped to adjacent transmission resources are discontinuous in Θ = { φ 1, φ 2,... φ K}.