mhurhangee/ep-ind-claims huggingface dataset:
Masitinib or a pharmaceutically acceptable salt or solvate thereof for use in the treatment of severe systemic mastocytosis in a human patient, wherein said severe systemic mastocytosis is associated with at least two mast cell mediator release associated handicaps selected from a pruritus score ≥ 9; a number of flushes per week ≥ 8; a Hamilton rating scale for depression (HAMD-17) score ≥ 19; a number of stools per day ≥ 4; a number of micturition per day ≥ 8; and a fatigue (asthenia) score measured by Fatigue Impact Scale ≥ 75, and wherein at least two mast cell mediator release associated handicaps are selected from a pruritus score ≥ 9; a number of flushes per week ≥ 8; and a HAMD-17 score ≥ 19, wherein said systemic mastocytosis is smoldering systemic mastocytosis or indolent systemic mastocytosis.
A method for producing a lubricating base oil, the method comprising: a first step of subjecting a synthetic wax obtained by a gas-to-liquid process, or a lubricating-oil fraction separated from the synthetic wax, to hydrocracking at a reaction temperature of 180 to 400°C and at a hydrogen partial pressure of 0.5 to 12 MPa, thereby obtaining a hydrocracked oil having a normal paraffin content of 30% or greater and 50% or less; and a second step of subjecting the hydrocracked oil to hydroisomerization dewaxing at a reaction temperature of 200 to 450°C in the presence of a hydroisomerization catalyst, thereby obtaining a lubricating base oil; wherein the lubricating base oil has a volume resistivity at 80°C of 1 TΩ·m or greater; and a volume resistivity at 25°C relative to the volume resistivity at 80°C that satisfies conditions represented by the following formula: B 25 ° C / A 80 ° C ≥ 1.5 wherein in formula, A (80°C) indicates the volume resistivity at 80°C of the lubricating base oil, and B (25°C) indicates the volume resistivity at 25°C of the lubricating base oil. a first step of subjecting a synthetic wax obtained by a gas-to-liquid process, or a lubricating-oil fraction separated from the synthetic wax, to hydrocracking at a reaction temperature of 180 to 400°C and at a hydrogen partial pressure of 0.5 to 12 MPa, thereby obtaining a hydrocracked oil having a normal paraffin content of 30% or greater and 50% or less; and a second step of subjecting the hydrocracked oil to hydroisomerization dewaxing at a reaction temperature of 200 to 450°C in the presence of a hydroisomerization catalyst, thereby obtaining a lubricating base oil; wherein the lubricating base oil has a volume resistivity at 80°C of 1 TΩ·m or greater; and a volume resistivity at 25°C relative to the volume resistivity at 80°C that satisfies conditions represented by the following formula: B 25 ° C / A 80 ° C ≥ 1.5 wherein in formula, A (80°C) indicates the volume resistivity at 80°C of the lubricating base oil, and B (25°C) indicates the volume resistivity at 25°C of the lubricating base oil.
A medical device comprising: an inert tubular adapter comprising a proximal rim arranged to be connectable to an inner lining of the stomach to encircle the esophageal sphincter, and a treatment element affixed to the inert tubular adapter; characterized in that: the device has an active state in which the treatment element is operative to constrict the passage of food to the stomach and an inactive state in which the treatment element is not operative, the treatment element having a delayed activation mechanism; the tubular adapter and the treatment element are arranged to be endoscopically inserted into the stomach by a single insertion procedure, with the treatment element in the inactive state, and the delayed activation mechanism is arranged to be mechanically or chemically self-activated or activated externally after a specified period following insertion. an inert tubular adapter comprising a proximal rim arranged to be connectable to an inner lining of the stomach to encircle the esophageal sphincter, and a treatment element affixed to the inert tubular adapter; characterized in that: the device has an active state in which the treatment element is operative to constrict the passage of food to the stomach and an inactive state in which the treatment element is not operative, the treatment element having a delayed activation mechanism; the device has an active state in which the treatment element is operative to constrict the passage of food to the stomach and an inactive state in which the treatment element is not operative, the treatment element having a delayed activation mechanism;
A composition comprising a polymer, wherein this polymer is water-soluble and has a melting point of at least 145° C, preferably at least 160° C, and comprises sulfonic acid groups, and an organic amine having at least two amino groups, wherein the organic amine having at least two amino groups is selected from the group consisting of ethylendiamine, diethylenetriamine, triethylendiamine, tetraethylenepentamine and tetrahydroxypropyl ethylenediamine. and optionally further cosmetic ingredients, preferably selected from the group consisting of solvents, rheology modifiers, preservatives, surfactants, emulsifiers, perfumes, pigments and coloring agents. a polymer, wherein this polymer is water-soluble and has a melting point of at least 145° C, preferably at least 160° C, and comprises sulfonic acid groups, and an organic amine having at least two amino groups, wherein the organic amine having at least two amino groups is selected from the group consisting of ethylendiamine, diethylenetriamine, triethylendiamine, tetraethylenepentamine and tetrahydroxypropyl ethylenediamine. and optionally further cosmetic ingredients, preferably selected from the group consisting of solvents, rheology modifiers, preservatives, surfactants, emulsifiers, perfumes, pigments and coloring agents.
A method for preparing a glycoside of a flavonoid compound, which comprises the step of treating the flavonoid compound and a glycosyl donor with an α-amylase from the genus Trichoderma, wherein the flavonoid compound is a catechin compound or a methylated derivative thereof in which H in at least one OH group is replaced by methyl; and wherein the glycosyl donor is maltotetraose, maltopentaose, maltohexaose, maltoheptaose, dextrin, γ-cyclodextrin or soluble starch; and wherein the glycoside of the flavonoid compound is represented by the following formula: wherein at least one of R 1 to R 4 represents an α-linked glucose residue, and each of the others represents OH; R 5 represents OH or H; and X represents H or a galloyl group. at least one of R 1 to R 4 represents an α-linked glucose residue, and each of the others represents OH; R 5 represents OH or H; and X represents H or a galloyl group.
A laser system having a predefined range of operating temperatures, the laser system comprising: a reflective chamber having a hemi-cylindrical shape and capable of housing a laser medium located on a flat inner surface of the reflective chamber, the laser medium having a peak absorption wavelength; and at least two laser diodes emitting light at different respective wavelengths into the reflective chamber through at least one elongated opening in the reflective chamber, the elongated opening having a long axis that is aligned with a long axis of the reflective chamber; wherein the wavelength of light emitted by each respective laser diode is selected such that the wavelength of light emitted by at least one laser diode is displaced from the peak absorption wavelength at all temperatures within the predefined range of operating temperatures. a reflective chamber having a hemi-cylindrical shape and capable of housing a laser medium located on a flat inner surface of the reflective chamber, the laser medium having a peak absorption wavelength; and at least two laser diodes emitting light at different respective wavelengths into the reflective chamber through at least one elongated opening in the reflective chamber, the elongated opening having a long axis that is aligned with a long axis of the reflective chamber; wherein the wavelength of light emitted by each respective laser diode is selected such that the wavelength of light emitted by at least one laser diode is displaced from the peak absorption wavelength at all temperatures within the predefined range of operating temperatures.
A computer-implemented method comprising: obtaining data representing a subterranean volume, the data having been collected by a user in a field; generating a digital model representing at least the subterranean volume based in part on the data; searching the digital model based in part on one or more metadata parameters; identifying one or more gaps in the model; and determining a data acquisition activity based on the one or more gaps that were identified in the model, the data acquisition activity specifying a type of data to be acquired, a location to collect the data, and acquisition equipment to be used in a subsequent data acquisition field trip; and outputting the data acquisition activity to be used in the field trip. obtaining data representing a subterranean volume, the data having been collected by a user in a field; generating a digital model representing at least the subterranean volume based in part on the data; searching the digital model based in part on one or more metadata parameters; identifying one or more gaps in the model; and determining a data acquisition activity based on the one or more gaps that were identified in the model, the data acquisition activity specifying a type of data to be acquired, a location to collect the data, and acquisition equipment to be used in a subsequent data acquisition field trip; and outputting the data acquisition activity to be used in the field trip.
Method for improving the accuracy of touch inputs on a touchscreen connected to a computer on which runs an operating system that is controllable using control elements presented on the touchscreen, wherein touching the touchscreen renders signals containing touch coordinates transmittable to the operating system in order for the operating system to check them for whether the screen has been touched in the region of the control elements, so as accordingly to perform a function, characterized by the steps: - intercepting the signals containing the touch coordinates before they are passed on to the operating system; - accessing the coordinates of the control elements of the operating system, and checking whether the touch coordinates are within a control element; - if the touch coordinates are within a control element, forwarding the touch coordinates to the operating system; - if the touch coordinates are not within any of the control elements, altering the touch coordinates, so that they are within the spatially closest control element, and forwarding the altered touch coordinates to the operating system. - intercepting the signals containing the touch coordinates before they are passed on to the operating system; - accessing the coordinates of the control elements of the operating system, and checking whether the touch coordinates are within a control element; - if the touch coordinates are within a control element, forwarding the touch coordinates to the operating system; - if the touch coordinates are not within any of the control elements, altering the touch coordinates, so that they are within the spatially closest control element, and forwarding the altered touch coordinates to the operating system.
A method of fabricating a micro-electrical-mechanical system (MEMS) microphone on a substrate, the method comprising: depositing first and second electrodes (113, 123); depositing a membrane, the membrane being mechanically coupled to the first electrode; and depositing a back plate, the back plate being mechanically coupled to the second electrode; wherein the step of depositing the membrane further comprises the step of depositing the membrane on a first sacrificial layer; and wherein the method further comprises the steps of: depositing a second sacrificial layer in an area between the first and second electrodes (113, 123); and removing the first and second sacrificial layers (109, 117) so as to form a MEMS microphone having a first cavity beneath the membrane, and a second cavity between the first and second electrodes, such that the membrane and the first electrode are able to move relative to the second electrode. depositing first and second electrodes (113, 123); depositing a membrane, the membrane being mechanically coupled to the first electrode; and depositing a back plate, the back plate being mechanically coupled to the second electrode; wherein the step of depositing the membrane further comprises the step of depositing the membrane on a first sacrificial layer; and wherein the method further comprises the steps of: depositing a second sacrificial layer in an area between the first and second electrodes (113, 123); and removing the first and second sacrificial layers (109, 117) so as to form a MEMS microphone having a first cavity beneath the membrane, and a second cavity between the first and second electrodes, such that the membrane and the first electrode are able to move relative to the second electrode. depositing a second sacrificial layer in an area between the first and second electrodes (113, 123); and removing the first and second sacrificial layers (109, 117) so as to form a MEMS microphone having a first cavity beneath the membrane, and a second cavity between the first and second electrodes, such that the membrane and the first electrode are able to move relative to the second electrode.
A polyethylene formulation comprising a partially cross-linked multimodal polyethylene composition having a first molecular weight ethylene-based polymer component and a second molecular weight ethylene-based polymer component, wherein the partially cross-linked multimodal polyethylene composition comprises: a density from 0.930 g/cc to 0.943 g/cc measured according to ASTM D792; a melt index (I 2) from 0.01 g/10 min to 5 g/10 min, when measured according to ASTM D1238 at 190 °C and a 2.16 kg load; a molecular weight distribution from 5 to 10, wherein MWD is defined as M w /M n with M w being a weight average molecular weight and M n being a number average molecular weight; and a complex viscosity ratio from 250 to 450, wherein the complex viscosity ratio is defined as the complex viscosity at a shear rate of 0.01 rad/s divided by the complex viscosity at a shear rate of 100 rad/s. a density from 0.930 g/cc to 0.943 g/cc measured according to ASTM D792; a melt index (I 2) from 0.01 g/10 min to 5 g/10 min, when measured according to ASTM D1238 at 190 °C and a 2.16 kg load; a molecular weight distribution from 5 to 10, wherein MWD is defined as M w /M n with M w being a weight average molecular weight and M n being a number average molecular weight; and a complex viscosity ratio from 250 to 450, wherein the complex viscosity ratio is defined as the complex viscosity at a shear rate of 0.01 rad/s divided by the complex viscosity at a shear rate of 100 rad/s.
A method performed by a user equipment, the method comprising: receiving downlink orthogonal frequency division multiplexing signals including a synchronization signal, where the synchronization signal is transmitted with a first subcarrier spacing and a first bandwidth; performing cell detection using the received downlink orthogonal frequency division multiplexing signals to detect at least one cell; selecting a cell of the at least one detected cell; receiving information of at least one subcarrier spacing associated with the selected cell, where the at least one subcarrier spacing is used for communication; selecting a second subcarrier spacing from the at least one subcarrier spacing; obtaining fine downlink timing information from an extended synchronization signal having a second bandwidth when the selected second subcarrier spacing is larger than the first subcarrier spacing; and transmitting using the fine downlink timing information. receiving downlink orthogonal frequency division multiplexing signals including a synchronization signal, where the synchronization signal is transmitted with a first subcarrier spacing and a first bandwidth; performing cell detection using the received downlink orthogonal frequency division multiplexing signals to detect at least one cell; selecting a cell of the at least one detected cell; receiving information of at least one subcarrier spacing associated with the selected cell, where the at least one subcarrier spacing is used for communication; selecting a second subcarrier spacing from the at least one subcarrier spacing; obtaining fine downlink timing information from an extended synchronization signal having a second bandwidth when the selected second subcarrier spacing is larger than the first subcarrier spacing; and transmitting using the fine downlink timing information.
A fixing system for a plate, a wall or the like, comprising: - a retaining member, having at least one through hole, - a rotating member, having at least one bore, extending along a central longitudinal axis of the rotating member, wherein the rotating member is insertable into the through hole of the retaining member; wherein the rotating member comprises a first portion and a second portion and - a fastening member configured to fasten the rotating member within the retaining member; characterized in that the first portion of the rotating member is disposed within the through hole of the retaining member with freedom of movement in radial direction therebetween, whereby the rotating member is slidable in the radial direction within the retaining member. - a retaining member, having at least one through hole, - a rotating member, having at least one bore, extending along a central longitudinal axis of the rotating member, wherein the rotating member is insertable into the through hole of the retaining member; wherein the rotating member comprises a first portion and a second portion and - a fastening member configured to fasten the rotating member within the retaining member;
Droplet separator comprising: a first number of blades arranged on a first carrier, each blade of the first number of blades comprising a first portion and a second portion which have a first obtuse angle formed between them; a second number of blades arranged on a second carrier, each blade of the second number of blades comprising a first portion and a second portion which have a second obtuse angle formed between them; wherein the blades of the first number of blades extend radially outward from the first carrier and wherein the blades of the second number of blades extend radially outward from the second carrier, characterized in that the first carrier and the second carrier are joined such that a blade of the second number of blades is arranged between two blades (101, 102) of the first number of blades. a first number of blades arranged on a first carrier, each blade of the first number of blades comprising a first portion and a second portion which have a first obtuse angle formed between them; a second number of blades arranged on a second carrier, each blade of the second number of blades comprising a first portion and a second portion which have a second obtuse angle formed between them; wherein the blades of the first number of blades extend radially outward from the first carrier and wherein the blades of the second number of blades extend radially outward from the second carrier, characterized in that the first carrier and the second carrier are joined such that a blade of the second number of blades is arranged between two blades (101, 102) of the first number of blades.
Use of at least one polypeptide chosen from type III polyketide synthases of algae, such as phloroglucinol synthase, with the exclusion of the type III polyketide synthases of Ectocarpus siliculosus chosen from PKS1.Es, PKS2.Es, PKS3.Es; said polypeptide comprising at least one amino acid sequence having at least 80% identity with a sequence chosen from SEQ ID NO: 3 and SEQ ID NO: 1.
A method for screening a request to establish a SIP session, comprising: a) receiving a first request to establish a SIP session at a network node of an internet protocol network and incrementing a received request counter to maintain a total request count; b) determining whether the first request includes a resource priority parameter with a first elevated priority value; c) comparing a priority request ratio to a predetermined priority request threshold, wherein the priority request ratio is indicative of a ratio of the priority request count to the total request count;and d) allowing processing for each first request that includes the first elevated priority value to continue in accordance with the first elevated priority value after the priority request ratio does not exceed the predetermined priority request threshold, and allowing processing for each first request that does not include the first elevated priority value to continue in accordance with a routine priority; characterized by: in b), if it is determined that the first request includes a resource priority parameter with a first priority value, incrementing an elevated priority request counter to maintain a priority request count; and in d), processing each first request that includes the elevated priority value using more comprehensive screening after the priority request ratio exceeds the predetermined priority request threshold. a) receiving a first request to establish a SIP session at a network node of an internet protocol network and incrementing a received request counter to maintain a total request count; b) determining whether the first request includes a resource priority parameter with a first elevated priority value; c) comparing a priority request ratio to a predetermined priority request threshold, wherein the priority request ratio is indicative of a ratio of the priority request count to the total request count;and d) allowing processing for each first request that includes the first elevated priority value to continue in accordance with the first elevated priority value after the priority request ratio does not exceed the predetermined priority request threshold, and allowing processing for each first request that does not include the first elevated priority value to continue in accordance with a routine priority; in b), if it is determined that the first request includes a resource priority parameter with a first priority value, incrementing an elevated priority request counter to maintain a priority request count; and in d), processing each first request that includes the elevated priority value using more comprehensive screening after the priority request ratio exceeds the predetermined priority request threshold.
Method for manufacturing a curved composite casing for a turbomachine, notably an aircraft turbojet engine, the method comprising the following steps: (a) draping a preform by automatic placement of carbon fibres on a concave form; (b) laying a glass-fibre ply on a convex form; (c) transferring the preform onto the convex form by covering the glass-fibre ply on the convex form. (a) draping a preform by automatic placement of carbon fibres on a concave form; (b) laying a glass-fibre ply on a convex form; (c) transferring the preform onto the convex form by covering the glass-fibre ply on the convex form.