mhurhangee/ep-ind-claims huggingface dataset:
A centrifugal separator for separation of a cell culture mixture, comprising a stationary frame, a rotatable assembly and a drive unit for rotating the rotatable assembly relative the frame around an axis of rotation, wherein the rotatable assembly comprises a rotor casing enclosing a separation space in which a stack of separation discs is arranged to rotate around a vertical axis of rotation; said rotor casing further comprising a mechanically hermetically sealed inlet for supply of said cell culture mixture to said separation space; a first mechanically hermetically sealed liquid outlet for discharge of a separated liquid phase and a second mechanically hermetically sealed liquid outlet for discharge of a separated cell phase; said cell phase having a density that is higher than said liquid phase; wherein said hermetically sealed inlet is arranged at a first axial end of said rotor casing and arranged so that the cell culture mixture to be separated enters said rotor casing at the rotational axis and; wherein said second mechanically hermetically sealed outlet is arranged at a second axial end of said rotor casing opposite said first end and arranged so that said separated cell phase is discharged at the rotational axis. a rotor casing enclosing a separation space in which a stack of separation discs is arranged to rotate around a vertical axis of rotation; said rotor casing further comprising a mechanically hermetically sealed inlet for supply of said cell culture mixture to said separation space; a first mechanically hermetically sealed liquid outlet for discharge of a separated liquid phase and a second mechanically hermetically sealed liquid outlet for discharge of a separated cell phase; said cell phase having a density that is higher than said liquid phase; wherein said hermetically sealed inlet is arranged at a first axial end of said rotor casing and arranged so that the cell culture mixture to be separated enters said rotor casing at the rotational axis and; wherein said second mechanically hermetically sealed outlet is arranged at a second axial end of said rotor casing opposite said first end and arranged so that said separated cell phase is discharged at the rotational axis.
A process for producing Syngas in a plasma reactor from a natural gas stream containing a significant quantity of CO 2, which process comprises: providing a natural gas stream that contains CH 4 and between about 2 and 40 volume % CO 2 and treating such stream in a semipermeable membrane device to provide a first permeate stream that is increased in CO 2 and contains CO 2 and CH 4 in an about 50/50 molar ratio for use as a first feedstream and provide a methane-rich concentrate stream containing at least about 90 volume % methane, combusting a substream from said concentrate stream with air in a cogeneration apparatus to produce electrical power, delivering an exhaust gas stream from said cogeneration apparatus to another semipermeable membrane device and separating a predominantly CO 2 permeate stream, blending said predominantly CO 2 permeate stream with a second substream of said methane-rich concentrate stream to create a second feedstream containing CO 2 and CH 4 in an about 50/50 molar ratio, delivering a composite feedstream, made up of said first feedstream and said second feedstream, containing CO 2 and CH 4 in about a 1:1 mole ratio with no more than a 2% excess of CO 2 to a microwave plasma reactor, which converts the CO 2 and methane to a stream of Syngas, whereby Syngas is produced in an environmentally friendly process from CO 2 -containing natural gas, which overall process is controlled to generate sufficient electric power to operate said membrane separation devices (12, 30) and said plasma reactor. providing a natural gas stream that contains CH 4 and between about 2 and 40 volume % CO 2 and treating such stream in a semipermeable membrane device to provide a first permeate stream that is increased in CO 2 and contains CO 2 and CH 4 in an about 50/50 molar ratio for use as a first feedstream and provide a methane-rich concentrate stream containing at least about 90 volume % methane, combusting a substream from said concentrate stream with air in a cogeneration apparatus to produce electrical power, delivering an exhaust gas stream from said cogeneration apparatus to another semipermeable membrane device and separating a predominantly CO 2 permeate stream, blending said predominantly CO 2 permeate stream with a second substream of said methane-rich concentrate stream to create a second feedstream containing CO 2 and CH 4 in an about 50/50 molar ratio, delivering a composite feedstream, made up of said first feedstream and said second feedstream, containing CO 2 and CH 4 in about a 1:1 mole ratio with no more than a 2% excess of CO 2 to a microwave plasma reactor, which converts the CO 2 and methane to a stream of Syngas, whereby Syngas is produced in an environmentally friendly process from CO 2 -containing natural gas, which overall process is controlled to generate sufficient electric power to operate said membrane separation devices (12, 30) and said plasma reactor.
A hydrogen desorption method comprising: bringing a liquid containing an alicyclic saturated hydrocarbon having a tertiary carbon atom bearing a saturated hydrocarbon side chain, a quinone, and an electrolyte into contact with an anode; and desorbing hydrogen from the alicyclic saturated hydrocarbon. bringing a liquid containing an alicyclic saturated hydrocarbon having a tertiary carbon atom bearing a saturated hydrocarbon side chain, a quinone, and an electrolyte into contact with an anode; and desorbing hydrogen from the alicyclic saturated hydrocarbon.
A method for repairing a partially collapsed subterranean pipe, the method comprising: fitting a mesh stent around the outside of an actuation assembly of a pipe repair apparatus, the actuation assembly comprising a plurality of arms; positioning the pipe repair apparatus within a portion of the pipe, at least a part of the portion of the pipe being partially collapsed; causing actuation, of at least one of the arms in the plurality of arms, between a retracted configuration in which the at least one arm exerts substantially no force against an interior surface of the pipe, and an extended configuration in which the at least one arm extends outwards to exert a force against the mesh stent and the interior surface of the pipe, such that the partially collapsed part of the pipe changes from a partially collapsed form towards a non-collapsed form; and removing the pipe repair apparatus from the pipe and leaving the mesh stent in the portion of the pipe such that the partially collapsed part of the pipe is held in the non-collapsed form by the mesh stent. fitting a mesh stent around the outside of an actuation assembly of a pipe repair apparatus, the actuation assembly comprising a plurality of arms; positioning the pipe repair apparatus within a portion of the pipe, at least a part of the portion of the pipe being partially collapsed; causing actuation, of at least one of the arms in the plurality of arms, between a retracted configuration in which the at least one arm exerts substantially no force against an interior surface of the pipe, and an extended configuration in which the at least one arm extends outwards to exert a force against the mesh stent and the interior surface of the pipe, such that the partially collapsed part of the pipe changes from a partially collapsed form towards a non-collapsed form; and removing the pipe repair apparatus from the pipe and leaving the mesh stent in the portion of the pipe such that the partially collapsed part of the pipe is held in the non-collapsed form by the mesh stent.
A composite compound structural component, particularly as semi-finished element, for application particularly in the aerospace sector, said component comprising: - at least two separate subpreforms (12, 13, 14) each separate subpreform (12, 13, 14) being at least two-dimensional and assembled of plies of fiber material, and - at least one connecting element (6, 15, 18, 19) made of plies of fibers connecting said separate subpreforms (12, 13, 14) to a stable semi-finished element, each connecting element having a curved part, being at least essentially two-dimensional and allowing coverage of various connections between said separate subpreforms (12, 13, 14) while supporting said subpreforms (12, 13, 14), wherein the at least one connecting element (6, 18, 19) is provided with at least one gusset filler (11, 16) arranged at the curved part of the at least one connecting element (6, 18, 19), said at least one gusset filler (11, 16) being adapted and projecting to the respective sides of any angle defined by said separate subpreforms (12, 13, 14), said separate subpreforms (12, 13, 14) being angular offset, characterized in that the at least one connecting element (6, 18, 19) is provided with at least one support layer (10, 17) for support of the gusset filler (10, 16), said support layer (10, 17) being partly attached to the at least one connecting element (6, 18, 19) and partly attached to the at least one gusset filler (10, 16). - at least two separate subpreforms (12, 13, 14) each separate subpreform (12, 13, 14) being at least two-dimensional and assembled of plies of fiber material, and - at least one connecting element (6, 15, 18, 19) made of plies of fibers connecting
A compound of the following Formula I: and pharmaceutically acceptable salts, enantiomers, polymorphs, solvates, or hydrates thereof, wherein: Ar is a heterocyclic aryl group selected from furan, methylfuran, pyrrole, imidazole, pyrazole, triazole, tetrazole, thiazole, isothiazole, methoxypyridine, pyridazine, pyrazine, triazine, indole, methylindole, benzofuran, benzothiophene, benzothiazole, isoquinoline, cinnoline, phthalazine, quinazoline, chromane and isochromane, and Ar is either unsubstituted or substituted with one or more substituents independently selected from fluoro, chloro, bromo, iodo, -NO 2, -CN, -NH 2, carboxy, C 2-8 alkenyl, C 2-8 alkynyl, halo(C 1-8)alkyl, hydroxy, trifluoromethyl, C 3-8 cycloalkyl, C 1-3 alkoxy, C 1-3 alkoxy(C 1-3)alkyl, carboxy(C 1-3)alkyl, C 1-3 alkanoyl, halo(C 1-3)alkoxyl, C 1-8 alkylamino, and di(C 1-8)alkylamino; and R 1 is selected from hydrogen, unsubstituted C 1-10 alkyl, C 3-8 cycloalkyl, C 2-10 alkenyl, and C 3-10 alkynyl, and substituted C 1-10 alkyl, C 3-10 alkenyl and C 3-10 alkynyl wherein the substituent is one or more of hydroxy, cyano, halogen, C 1-6 alkoxy, aryl substituted C 1-6 alkoxy, aryloxy, aryloxy substituted with one or more halogens, C 1-6 alkyl, C 1-6 alkyl independently substituted with one or more of cyano and halogen, C 1-4 alkoxy, and C 1-4 haloalkoxy. Ar is a heterocyclic aryl group selected from furan, methylfuran, pyrrole, imidazole, pyrazole, triazole, tetrazole, thiazole, isothiazole, methoxypyridine, pyridazine, pyrazine, triazine, indole, methylindole, benzofuran, benzothiophene, benzothiazole, isoquinoline, cinnoline, phthalazine, quinazoline, chromane and isochromane, and Ar is either unsubstituted or substituted with one or more substituents independently selected from fluoro, chloro, bromo, iodo, -NO 2, -CN, -NH 2, carboxy, C 2-8 alkenyl, C 2-8 alkynyl, halo(C 1-8)alkyl, hydroxy, trifluoromethyl, C 3-8 cycloalkyl, C 1-3 alkoxy, C 1-3 alkoxy(C 1-3)alkyl, carboxy(C 1-3)alkyl, C 1-3 alkanoyl, halo(C 1-3)alkoxyl, C 1-8 alkylamino, and di(C 1-8)alkylamino; and R 1 is selected from hydrogen, unsubstituted C 1-10 alkyl, C 3-8 cycloalkyl, C 2-10 alkenyl, and C 3-10 alkynyl, and substituted C 1-10 alkyl, C 3-10 alkenyl and C 3-10 alkynyl wherein the substituent is one or more of hydroxy, cyano, halogen, C 1-6 alkoxy, aryl substituted C 1-6 alkoxy, aryloxy, aryloxy substituted with one or more halogens, C 1-6 alkyl, C 1-6 alkyl independently substituted with one or more of cyano and halogen, C 1-4 alkoxy, and C 1-4 haloalkoxy.
An injection device comprising: a dispensing chamber having an inner surface and an outer surface, the inner surface defining a cavity for receiving a quantity of a substance; a plunger engaged with the inner surface of the dispensing chamber, the plunger capable of sliding in the cavity of the dispensing chamber, the plunger fluidly sealed to the inner surface of the dispensing chamber; a controller for controlling the operation of the injection device; a fuse, adapted such that after the substance has been delivered from the dispensing chamber, the fuse is blown, thereby preventing reuse of the device; and a temperature control device at least partially surrounding the dispensing chamber; a memory device having a parameter stored on the memory device, wherein the parameter is a dosage information or delivery rate information parameter wherein the controller is adapted to use the dosage information or delivery rate information parameter from the memory device to operate the injection device; characterized in that the memory device is a hard-wired memory device that comprises multiple pairs of a fuse (F1-F6) and a resistor (R1-R6), each fuse and resistor connected in series, the multiple pairs of a fuse and a resistor being connected in parallel. a dispensing chamber having an inner surface and an outer surface, the inner surface defining a cavity for receiving a quantity of a substance; a plunger engaged with the inner surface of the dispensing chamber, the plunger capable of sliding in the cavity of the dispensing chamber, the plunger fluidly sealed to the inner surface of the dispensing chamber; a controller for controlling the operation of the injection device; a fuse, adapted such that after the substance has been delivered from the dispensing chamber, the fuse is blown, thereby preventing reuse of the device; and a temperature control device at least partially surrounding the dispensing chamber; a memory device having a parameter stored on the memory device, wherein the parameter is a dosage information or delivery rate information parameter wherein the controller is adapted to use the dosage information or delivery rate information parameter from the memory device to operate the injection device; characterized in that the memory device is a hard-wired memory device that comprises multiple pairs of a fuse (F1-F6) and a resistor (R1-R6), each fuse and resistor connected in series, the multiple pairs of a fuse and a resistor being connected in parallel.
A method for amplifying a nucleic acid by multiple displacement amplification, comprising: a) providing a target nucleic acid template; b) contacting the target nucleic acid template with a reaction mixture comprising a DNA polymerase having a strand displacement activity, a deoxyribonucleoside triphosphate (dNTP) mixture, a random hexamer primer with a 3' end and a 5' end, a molecular crowding reagent, and a buffer solution, wherein the buffer solution maintains a KCl concentration of the reaction mixture of 20 mM; and c) amplifying the target nucleic acid template under isothermal amplification conditions at a constant reaction temperature of 30°C, wherein the KCl concentration results in a melting temperature (T m) of the primer at least 10°C below the reaction temperature,: and wherein the molecular crowding reagent is selected from a group consisting of a PEG 400, PEG 2000, PEG 6000, PEG 8000 or combinations thereof in a concentration of 2.5%. a) providing a target nucleic acid template; b) contacting the target nucleic acid template with a reaction mixture comprising a DNA polymerase having a strand displacement activity, a deoxyribonucleoside triphosphate (dNTP) mixture, a random hexamer primer with a 3' end and a 5' end, a molecular crowding reagent, and a buffer solution, wherein the buffer solution maintains a KCl concentration of the reaction mixture of 20 mM; and c) amplifying the target nucleic acid template under isothermal amplification conditions at a constant reaction temperature of 30°C,
A mouthpiece for a setting device setting a blind rivet element (50; 50'), comprising: a. a hollow, preferably a hollow-cylindrical, body having an abutting end and a central through bore through which a pulling component of the setting device is movable, said mouthpiece being characterised by further comprising: b. a first endless sealing being arranged adjacent to the central through bore at the abutting end for abutting at a head portion of the blind rivet element, c. a second endless sealing being arranged radially outwardly of the first endless sealing at the abutting end for abutting at a component, and d. a fluid channel extending at least partly through the hollow, preferably a hollow-cylindrical, body such that an exit opening is provided between the first and the second endless sealing and an entry opening for supplying a testing fluid is provided, preferably remote, to the abutting end. a. a hollow, preferably a hollow-cylindrical, body having an abutting end and a central through bore through which a pulling component of the setting device is movable, said mouthpiece being characterised by further comprising: b. a first endless sealing being arranged adjacent to the central through bore at the abutting end for abutting at a head portion of the blind rivet element, c. a second endless sealing being arranged radially outwardly of the first endless sealing at the abutting end for abutting at a component, and d. a fluid channel extending at least partly through the hollow, preferably a hollow-cylindrical, body such that an exit opening is provided between the first and the second endless sealing and an entry opening for supplying a testing fluid is provided, preferably remote, to the abutting end. b. a first endless sealing being arranged adjacent to the central through bore at the abutting end for abutting at a head portion of the blind rivet element, c. a second endless sealing being arranged radially outwardly of the first endless sealing at the abutting end for abutting at a component, and d. a fluid channel extending at least partly through the hollow, preferably a hollow-cylindrical, body such that an exit opening is provided between the first and the second endless sealing and an entry opening for supplying a testing fluid is provided, preferably remote, to the abutting end.
A flow sensor for an internal combustion engine control system of a vehicle including a sub-passage constituting a measurement channel by taking in a measured fluid from an opening, a flow rate detector arranged inside the sub-passage to measure a flow rate of the measured fluid, a housing isolated from the sub-passage in a circuit chamber to house electronic components that drive the flow rate detector, and resin cover joined to the housing to airtightly seal the sub-passage and the circuit chamber from an outside air wherein a joining portion formed on the housing and a joining portion formed on an inner surface of the cover are joined by using an adhesive or by laser welding, characterized in that, the cover contains a crystalline resin as a main material and contains at least one non-crystalline alloy material, the cover has a natural color, and a glass transition temperature of the alloy material contained in the resin material of the cover is 80°C to 120°C.
The compound of formula IX: wherein Ar is 3,4-dichloro-5-fluoro-phenyl and R 1 is C 3-6 alkyl; aryl-C 1-6 alkyl; C 3-6 cycloalkyl-C 1-6 alkyl; hetero-C 1-6 alkyl; halo-C 1-6 alkyl; or C 1-6 -alkyl-C 1-3 cycloalkyl-C 1-6 alkyl. wherein Ar is 3,4-dichloro-5-fluoro-phenyl and R 1 is C 3-6 alkyl; aryl-C 1-6 alkyl; C 3-6 cycloalkyl-C 1-6 alkyl; hetero-C 1-6 alkyl; halo-C 1-6 alkyl; or C 1-6 -alkyl-C 1-3 cycloalkyl-C 1-6 alkyl. C 3-6 alkyl; aryl-C 1-6 alkyl; C 3-6 cycloalkyl-C 1-6 alkyl; hetero-C 1-6 alkyl; halo-C 1-6 alkyl; or C 1-6 -alkyl-C 1-3 cycloalkyl-C 1-6 alkyl.
An apparatus for installing at least one electrical contact into a connector housing, the apparatus comprising: a base configured to fixedly support the connector housing; an alignment guide extending from the base and having a central axis, wherein, with the connector housing fixedly supported by the base, the alignment guide is configured to be parallel to an insertion axis of a socket of the connector housing; a carrier translatably and pivotally coupled with the alignment guide, wherein, with the connector housing fixedly supported by the base, the carrier is movable parallel to the insertion axis of the socket of the connector housing; and a tool holder coupled to the carrier, wherein the tool holder has a working axis and only three degrees of freedom relative to the base; wherein the tool holder comprises a coupler configured to removably retain an insertion tool in the tool holder; characterized in that the carrier comprises a sleeve and a carrier arm that is configured to be fixed to the sleeve and is rotatably coupled with the tool holder; wherein the carrier arm is configured to be releasably fixed to the sleeve; and wherein the carrier arm is selectively repositionable relative to the sleeve along the central axis, which is configured to be parallel to the insertion axis of the socket, to adjust a minimum distance between the tool holder and the base. a base configured to fixedly support the connector housing; an alignment guide extending from the base and having a central axis, wherein, with the connector housing fixedly supported by the base, the alignment guide is configured to be parallel to an insertion axis of a socket of the connector housing; a carrier translatably and pivotally coupled with the alignment guide, wherein, with the connector housing fixedly supported by the base, the carrier is movable parallel to the insertion axis of the socket of the connector housing; and a tool holder coupled to the carrier, wherein the tool holder has a working axis and only three degrees of freedom relative to the base; wherein the tool holder comprises a coupler configured to removably retain an insertion tool in the tool holder; characterized in that the carrier comprises a sleeve and a carrier arm that is configured to be fixed to the sleeve and is rotatably coupled with the tool holder; wherein the carrier arm is configured to be releasably fixed to the sleeve; and wherein the carrier arm is selectively repositionable relative to the sleeve along the central axis, which is configured to be parallel to the insertion axis of the socket, to adjust a minimum distance between the tool holder and the base.
A double-stranded short interfering nucleic acid (siNA) molecule that inhibits the expression of CTNNB1, wherein the siNA comprises: 5'-ACGACUAGUUCAGUUGCUU-3' (SEQ ID NO: 194) and 5'-AAGCAACUGAACUAGUCGU-3' (SEQ ID NO: 5107). 5'-ACGACUAGUUCAGUUGCUU-3' (SEQ ID NO: 194) and 5'-AAGCAACUGAACUAGUCGU-3' (SEQ ID NO: 5107).