A cleaning system for removing debris from an interior wall of an endotracheal tube having an internal lumen, comprising: a non-inflatable mechanically-actuatable cleaning device, comprising: an elongate body having a proximal end and a distal end, said elongate body comprising at least one internal lumen extending along at least a portion of a length of the elongate body and a closed distal tip having a viewing window that is at least partially optically transparent; a non-inflatable, mechanically-expandable cleaning member positioned along an exterior surface of the elongate body, wherein said cleaning member comprises a mesh scaffold adapted to selectively move between a radially-collapsed position and a radially-expanded position and an expandable removal member positioned, at least partially, along the outside of the mesh scaffold such that the removal member is adapted to collapse and expand with the movement of the mesh scaffold, wherein said removal member and said mesh scaffold are separate items that are permanently or removably attached to each other, wherein said removal member is configured to engage an interior surface of an endotracheal tube when the mesh scaffold is in a radially-expanded position, wherein said removal member is configured to remove debris collected on the interior surface of the endotracheal tube when said cleaning member is moved along a longitudinal axis of the endotracheal tube; and a mechanical actuation assembly coupled to the proximal end of the elongate body; wherein the mesh scaffold is configured to move between the radially-collapsed position and the radially-expanded position by manipulation of the actuation assembly, wherein expansion and collapse of the scaffold occurs mechanically; and wherein said at least one internal lumen is configured to receive a visualization scope. a non-inflatable mechanically-actuatable cleaning device, comprising: an elongate body having a proximal end and a distal end, said elongate body comprising at least one internal lumen extending along at least a portion of a length of the elongate body and a closed distal tip having a viewing window that is at least partially optically transparent; a non-inflatable, mechanically-expandable cleaning member positioned along an exterior surface of the elongate body, wherein said cleaning member comprises a mesh scaffold adapted to selectively move between a radially-collapsed position and a radially-expanded position and an expandable removal member positioned, at least partially, along the outside of the mesh scaffold such that the removal member is adapted to collapse and expand with the movement of the mesh scaffold, wherein said removal member and said mesh scaffold are separate items that are permanently or removably attached to each other, wherein said removal member is configured to engage an interior surface of an endotracheal tube when the mesh scaffold is in a radially-expanded position, wherein said removal member is configured to remove debris collected on the interior surface of the endotracheal tube when said cleaning member is moved along a longitudinal axis of the endotracheal tube; and a mechanical actuation assembly coupled to the proximal end of the elongate body; wherein the mesh scaffold is configured to move between the radially-collapsed position and the radially-expanded position by manipulation of the actuation assembly, wherein expansion and collapse of the scaffold occurs mechanically; and wherein said at least one internal lumen is configured to receive a visualization scope. an elongate body having a proximal end and a distal end, said elongate body comprising at least one internal lumen extending along at least a portion of a length of the elongate body and a closed distal tip having a viewing window that is at least partially optically transparent; a non-inflatable, mechanically-expandable cleaning member positioned along an exterior surface of the elongate body, wherein said cleaning member comprises a mesh scaffold adapted to selectively move between a radially-collapsed position and a radially-expanded position and an expandable removal member positioned, at least partially, along the outside of the mesh scaffold such that the removal member is adapted to collapse and expand with the movement of the mesh scaffold, wherein said removal member and said mesh scaffold are separate items that are permanently or removably attached to each other, wherein said removal member is configured to engage an interior surface of an endotracheal tube when the mesh scaffold is in a radially-expanded position, wherein said removal member is configured to remove debris collected on the interior surface of the endotracheal tube when said cleaning member is moved along a longitudinal axis of the endotracheal tube; and a mechanical actuation assembly coupled to the proximal end of the elongate body; wherein the mesh scaffold is configured to move between the radially-collapsed position and the radially-expanded position by manipulation of the actuation assembly, wherein expansion and collapse of the scaffold occurs mechanically; and wherein said at least one internal lumen is configured to receive a visualization scope.