mhurhangee/ep-ind-claims huggingface dataset:
A method for preparing cerium oxide particles, comprising at least the steps of: (a) providing a cerium salt solution comprising anions and cations, wherein between 90 and 100 mol % of the cerium cations are tetravalent cerium cations; (b) heating said cerium salt solution at a temperature comprised between 60 and 220°C in order to obtain a suspension comprising a liquid medium and a precipitate; (c) decreasing the concentration of anions from the cerium salt present in the liquid medium between 10 and 90 mol %, in comparison with said anions comprised in the liquid medium in step (b); (d) heating the suspension obtained in step (c) at a temperature comprised between 100 and 300°C; (e) optionally cooling the suspension obtained in the step (d); (f) bringing said suspension into contact with a basic compound; (g) optionally separating off the precipitate from the liquid medium; (h) adding an organic texturing agent to the suspension obtained in step (f) or the precipitate obtained in step (g), the organic texturing agent being selected in the group of carboxylic acids and their salts; (i) optionally separating off the precipitate from the liquid medium; and (j) calcining the precipitate obtained at the end of step (h) or obtained at step (i) to obtain cerium oxide particles; said process of the invention comprising at least said step (g) and/or at said step (i). (a) providing a cerium salt solution comprising anions and cations, wherein between 90 and 100 mol % of the cerium cations are tetravalent cerium cations; (b) heating said cerium salt solution at a temperature comprised between 60 and 220°C in order to obtain a suspension comprising a liquid medium and a precipitate; (c) decreasing the concentration of anions from the cerium salt present in the liquid medium between 10 and 90 mol %, in comparison with said anions comprised in the liquid medium in step (b); (d) heating the suspension obtained in step (c) at a temperature comprised between 100 and 300°C; (e) optionally cooling the suspension obtained in the step (d); (f) bringing said suspension into contact with a basic compound; (g) optionally separating off the precipitate from the liquid medium; (h) adding an organic texturing agent to the suspension obtained in step (f) or the precipitate obtained in step (g), the organic texturing agent being selected in the group of carboxylic acids and their salts; (i) optionally separating off the precipitate from the liquid medium; and (j) calcining the precipitate obtained at the end of step (h) or obtained at step (i) to obtain cerium oxide particles; said process of the invention comprising at least said step (g) and/or at said step (i).
A method of detecting uncontrolled combustion in a dual-fuel internal combustion engine of an engine system, the engine system comprising an in-cylinder pressure sensor configured to measure pressure in a cylinder of the engine and generate a corresponding pressure signal and a crank angle sensor configured to measure the crank angle of the engine and generate a corresponding crank angle signal, a controller comprising a processor couplable to the in-cylinder pressure sensor and the crank angle sensor, the method comprising: sampling a pressure signal from the in-cylinder pressure sensor, the pressure signal representative of a measured pressure in a cylinder of the engine; calculating combustion metrics based on the pressure signal, the combustion metrics being at least a peak cylinder pressure, a rate of cylinder pressure rise, a cylinder pressure ripple, a burn duration, and a slope of heat release; calculating a combustion intensity metric based on the pressure signal, wherein the combustion intensity metric is an indicator of the engine's proximity to an uncontrolled combustion condition, and wherein the combustion intensity metric is a function of at least the peak cylinder pressure, the rate of cylinder pressure rise, the cylinder pressure ripple, the burn duration, and the slope of heat release; determining an engine control parameter as a function of the combustion intensity metric, wherein the engine control parameter comprises a substitution rate of a first fuel and a second fuel based on the combustion intensity metric; and controlling the engine based on the engine control parameter. sampling a pressure signal from the in-cylinder pressure sensor, the pressure signal representative of a measured pressure in a cylinder of the engine; calculating combustion metrics based on the pressure signal, the combustion metrics being at least a peak cylinder pressure, a rate of cylinder pressure rise, a cylinder pressure ripple, a burn duration, and a slope of heat release; calculating a combustion intensity metric based on the pressure signal, wherein the combustion intensity metric is an indicator of the engine's proximity to an uncontrolled combustion condition, and wherein the combustion intensity metric is a function of at least the peak cylinder pressure, the rate of cylinder pressure rise, the cylinder pressure ripple, the burn duration, and the slope of heat release; determining an engine control parameter as a function of the combustion intensity metric, wherein the engine control parameter comprises a substitution rate of a first fuel and a second fuel based on the combustion intensity metric; and controlling the engine based on the engine control parameter.
Plate heat exchanger comprising at least two heat exchanger blocks (10a, 10b), each heat exchanger block (10a, 10b) having multiple sheets that are arranged parallel to one another and form a plurality of heat-exchange passages for fluids involved in the heat exchange, the heat exchanger blocks (10a, 10b) being connected to one another by way of connecting means and having at least one common header for distributing a heat-exchanging fluid to the two heat exchanger blocks (10a, 10b) or for draining a heat-exchanging fluid from the two heat exchanger blocks (10a, 10b), characterized in that in an interspace of adjacent heat exchanger blocks (10a, 10b) that is present between opposing outer surfaces (14a, 14b) there is metal foam, which connects the outer surfaces (14a, 14b) to one another.
A magnetic resonance imaging inductively-coupled wireless tracking marker for three-dimensional positional tracking comprising: a plurality of double layered flexible printed circuit sheets; at least first and second conductive planar coils disposed on respective sides of each flexible printed circuit sheet, the coils having a resonant frequency corresponding to a Larmor frequency of a magnetic resonance imaging scanner, each of the coils forming a spiral inductor, the at least first and second planar coils being coupled to each other to provide a mutual coupling effect between the at least first and second planar coils; capacitors connected to each of the planar coils; each of the planar coils being formed from a magnetic resonance imaging-compatible non-ferromagnetic material wherein each flexible printed circuit sheet is encapsulated in a biocompatible and magnetic resonance compatible material, and the flexible printed circuit sheets are bonded together with an adhesive to form a multilayer coil. a plurality of double layered flexible printed circuit sheets; at least first and second conductive planar coils disposed on respective sides of each flexible printed circuit sheet, the coils having a resonant frequency corresponding to a Larmor frequency of a magnetic resonance imaging scanner, each of the coils forming a spiral inductor, the at least first and second planar coils being coupled to each other to provide a mutual coupling effect between the at least first and second planar coils; capacitors connected to each of the planar coils; each of the planar coils being formed from a magnetic resonance imaging-compatible non-ferromagnetic material
A method of managing the weight of an animal comprising: providing a measuring device comprising a container having a first side with a cavity and a second opposing side having a cavity that is larger than the cavity of the first side; feeding to the animal an amount of food that fills the cavity of the first side for a length of time to achieve a desired weight in the animal; and feeding to the animal an amount of food that fills the cavity of the second side to maintain the weight of the animal after the animal has achieved the desired weight. providing a measuring device comprising a container having a first side with a cavity and a second opposing side having a cavity that is larger than the cavity of the first side; feeding to the animal an amount of food that fills the cavity of the first side for a length of time to achieve a desired weight in the animal; and feeding to the animal an amount of food that fills the cavity of the second side to maintain the weight of the animal after the animal has achieved the desired weight.
Stack of layers (100, 101), comprising: • a first layer made of an anisotropic magnetostrictive material including at least one preferential axis of deformation (4, 5) in the plane defined by said layer, the first layer having at least one mark, such as a flattening or a notch on an edge of said layer or an engraving on one face of said layer, or being provided with at least one locating means, locating a preferential axis of deformation (4, 5); • a second layer made of a piezoelectric material having a first axis of polarization in the plane defined by the second layer parallel to the plane defined by the first layer, the first axis of polarization being located by a second mark; the first axis of polarization and the preferential axis of deformation (4, 5) being aligned to within 15°. • a first layer made of an anisotropic magnetostrictive material including at least one preferential axis of deformation (4, 5) in the plane defined by said layer, the first layer having at least one mark, such as a flattening or a notch on an edge of said layer or an engraving on one face of said layer, or being provided with at least one locating means, locating a preferential axis of deformation (4, 5); • a second layer made of a piezoelectric material having a first axis of polarization in the plane defined by the second layer parallel to the plane defined by the first layer, the first axis of polarization being located by a second mark;
An antibody or an antigen-binding fragment thereof that specifically binds and inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9) for use in a method for reducing cardiovascular risk in a high cardiovascular risk patient following an acute coronary syndrome event, wherein said patient has hypercholesterolemia and exhibits inadequate control of other atherogenic lipoproteins despite treatment with a maximum tolerated daily dose statin therapy, wherein the antibody or the antigen-binding fragment thereof has heavy and light chain CDR amino acid sequences having SEQ ID NOs: 2 (HCDR1), 3 (HCDR2), 4 (HCDR3), 7 (LCDR1), 8 (LCDR2) and 10 (LCDR3), and wherein the use comprises administering the antibody or antigen-binding fragment thereof to the patient at a dose of 75 mg or 150 mg.
A pressure reducer for reducing a fluid pressure comprising: a pressure reducer body defining at least one pressure reducer chamber along a central axis ( X-X'), the pressure reducer chamber including: an inlet section and an outlet section fluidly coupled with the inlet section such that the inlet section and the outlet section allow inlet and outlet of the fluid respectively; a spring-operated piston rod; a sealing component operatively coupled with the piston rod in the pressure reducer chamber for preventing fluid in the outlet section from leaking back to the pressure reducer chamber; a valve, wherein the valve opens and closes due to rocking motion of the piston rod, and wherein the valve is coupled to the inlet section of the pressure reducer chamber; and a sealing element disposed between the valve and the piston rod, wherein the piston rod is configured to stop a supply of fluid by engagement with the sealing element of the valve; characterized in that: the valve defines a sealing seat for the sealing element, wherein the sealing element rests upon the sealing seat; and, when the piston rod stops the supply of fluid, the piston rod is sealed radially by the sealing element to prevent the fluid from entering the piston rod. a pressure reducer body defining at least one pressure reducer chamber along a central axis ( X-X'), the pressure reducer chamber including: an inlet section and an outlet section fluidly coupled with the inlet section such that the inlet section and the outlet section allow inlet and outlet of the fluid respectively; a spring-operated piston rod; a sealing component operatively coupled with the piston rod in the pressure reducer chamber for preventing fluid in the outlet section from leaking back to the pressure reducer chamber; a valve, wherein the valve opens and closes due to rocking motion of the piston rod, and wherein the valve is coupled to the inlet section of the pressure reducer chamber; and a sealing element disposed between the valve and the piston rod, wherein the piston rod is configured to stop a supply of fluid by engagement with the sealing element of the valve; the valve defines a sealing seat for the sealing element, wherein the sealing element rests upon the sealing seat; and, when the piston rod stops the supply of fluid, the piston rod is sealed radially by the sealing element to prevent the fluid from entering the piston rod.
Method for producing an injection valve having an injection-moulded encapsulation, comprising the steps: - providing an injection assembly, - pushing a disk-shaped alignment element onto a part of the injection assembly, wherein the alignment element has a slot in order to exhibit adequate flexibility, - welding the alignment element onto the part of the injection assembly, wherein, during the welding-on step, at least a part of the slot is simultaneously welded closed in order to stiffen the alignment element, and - injection-moulding the injection-moulded encapsulation onto the injection assembly. - providing an injection assembly, - pushing a disk-shaped alignment element onto a part of the injection assembly, wherein the alignment element has a slot in order to exhibit adequate flexibility, - welding the alignment element onto the part of the injection assembly, wherein, during the welding-on step, at least a part of the slot is simultaneously welded closed in order to stiffen the alignment element, and - injection-moulding the injection-moulded encapsulation onto the injection assembly.
A switching circuit for providing a switched current source output, comprising: a reference voltage input device (Vref), which comprises a reference voltage charge storage device (Cref); a gate voltage charge storage arrangement (Cbuf) for storing a precharge voltage derived from the reference voltage (Vref); a reference current source (Iref) providing a reference current; an output transistor (Mout); a current sensing transistor (Msense) for generating a sense current (Isense) dependent on the current source output and which is supplied by the reference current source (Iref); an isolating switch arrangement for selectively coupling or isolating the gate of the output transistor (Mout) and the gate of the current sensing transistor (Msense) to or from the gate voltage charge storage arrangement (Cbuf); a discharge switch arrangement for discharging the gate of the output transistor (Mout) and the gate of the current sensing transistor (Msense); a feedback loop for controlling the reference voltage (Vref) stored on the reference voltage charge storage device (Cref) to maintain the sense current (Isense) substantially equal to the reference current (Iref); wherein the reference voltage input device comprises a comparator, which depending on the sign of a difference between the reference current and the sense current, controls the charging or discharging of the reference voltage charge storage device, and a pull up current source and a pull down current source, wherein the comparator output is used to couple a selected one of the pull up and pull down current sources to the reference voltage charge storage device. a reference voltage input device (Vref), which comprises a reference voltage charge storage device (Cref); a gate voltage charge storage arrangement (Cbuf) for storing a precharge voltage derived from the reference voltage (Vref); a reference current source (Iref) providing a reference current; an output transistor (Mout); a current sensing transistor (Msense) for generating a sense current (Isense) dependent on the current source output and which is supplied by the reference current source (Iref); an isolating switch arrangement for selectively coupling or isolating the gate of the output transistor (Mout) and the gate of the current sensing transistor (Msense) to or from the gate voltage charge storage arrangement (Cbuf); a discharge switch arrangement for discharging the gate of the output transistor (Mout) and the gate of the current sensing transistor (Msense); a feedback loop for controlling the reference voltage (Vref) stored on the reference voltage charge storage device (Cref) to maintain the sense current (Isense) substantially equal to the reference current (Iref); wherein the reference voltage input device comprises a comparator, which depending on the sign of a difference between the reference current and the sense current, controls the charging or discharging of the reference voltage charge storage device, and a pull up current source and a pull down current source, wherein the comparator output is used to couple a selected one of the pull up and pull down current sources to the reference voltage charge storage device.
A transdermal delivery device comprising a pharmaceutical composition, wherein said composition comprises a N-oxide derivative of an opioid antagonist of formula, or a salt thereof, and an opioid agonist or salt thereof: wherein R 1 is selected from optionally substituted C 1-8 alkyl and optionally substituted C 2-8 alkenyl; R 2 is selected from OH, H, OC 1-8 alkyl, NHCOR, NR 1 COR, CONR 1 R and CONHR wherein R is a hydrocarbyl group or R 2 forms a bridge to the carbon to which R 3 is attached; R 3 is selected from O, CH 2, N-NH 2 or a linking group to a second N-oxide derivative of an opioid antagonist or a salt thereof when the dashed bond is present and is selected from OH, H, OC 1-8 alkyl, OCOR 1, O(CH 2 CH 2 (CH 2) y O) x CH 3 wherein x is 1-10 and y is 0-3, N(R 1) 2, NR 1 COR, NHCOR, CONR 1 R, CONHR, wherein R is a hydrocarbyl group, or a linking group to a second N-oxide derivative of an opioid antagonist or a salt thereof, when the dashed bond is absent and R 4 is selected from H, CONHR, CONR 1 R, NHCOR, NR 1 COR and C (R 1) 2, wherein R is a hydrocarbyl group; or R 3 and R 4, together with the carbon atoms to which they are attached form a heterocycle or a linking group to a second N-oxide derivative of an opioid antagonist or a salt thereof; R 5 is selected from OH, OC 1-8 alkyl, OCOR 1, H and CONH 2; R 6 and R 7 are each independently selected from H, OH and OC 1-8 alkyl or R 6 and R 7, together with the carbon atoms to which they are attached, form a dihydrofuran ring; and each dashed bond in the cyclohexyl ring may be present or absent with the proviso that both may not be present. R 1 is selected from optionally substituted C 1-8 alkyl and optionally substituted C 2-8 alkenyl; R 2 is selected from OH, H, OC 1-8 alkyl, NHCOR, NR 1 COR, CONR 1 R and CONHR wherein R is a hydrocarbyl group or R 2 forms a bridge to the carbon to which R 3 is attached; R 3 is selected from O, CH 2, N-NH 2 or a linking group to a second N-oxide derivative of an opioid antagonist or a salt thereof when the dashed bond is present and is selected from OH, H, OC 1-8 alkyl, OCOR 1, O(CH 2 CH 2 (CH 2) y O) x CH 3 wherein x is 1-10 and y is 0-3, N(R 1) 2, NR 1 COR, NHCOR, CONR 1 R, CONHR, wherein R is a hydrocarbyl group, or a linking group to a second N-oxide derivative of an opioid antagonist or a salt thereof, when the dashed bond is absent and R 4 is selected from H, CONHR, CONR 1 R, NHCOR, NR 1 COR and C (R 1) 2, wherein R is a hydrocarbyl group; or R 3 and R 4, together with the carbon atoms to which they are attached form a heterocycle or a linking group to a second N-oxide derivative of an opioid antagonist or a salt thereof; R 5 is selected from OH, OC 1-8 alkyl, OCOR 1, H and CONH 2; R 6 and R 7 are each independently selected from H, OH and OC 1-8 alkyl or R 6 and R 7, together with the carbon atoms to which they are attached, form a dihydrofuran ring; and each dashed bond in the cyclohexyl ring may be present or absent with the proviso that both may not be present.
Device for closing containers with a closure, comprising a closure cone for applying the closure to the container and a picking wheel for transferring the closure to the closure cone, wherein the picking wheel is designed so as to be concentric with the path on which the closure cone is guided, characterized in that the picking wheel comprises at least one mobile segment which is movable from a carrying position for carrying the closure from a closure infeed to a transfer position for transferring the closure to the closure cone, and that at least one segment is movable in relation to the rotation plane of the picking wheel.
A method of creating a background reference frame at a video decoder, the method comprising: at each of a plurality of time intervals, receiving one or more coded portions of a background reference frame from a video encoder; decoding the one or more portions; storing the one or more decoded portions in a buffer such that, after the plurality of time intervals, some or all of a background reference frame is stored in the buffer; receiving an encoded updated portion of the background reference frame; decoding the updated portion to produce a decoded updated portion; and overwriting the corresponding portion of the background reference frame in the buffer using the decoded updated portion in response to determining, at the video decoder, that the updated portion is of superior quality relative to the corresponding portion of the background reference frame in the buffer, characterised in that the determination is made using a quality parameter. at each of a plurality of time intervals, receiving one or more coded portions of a background reference frame from a video encoder; decoding the one or more portions; storing the one or more decoded portions in a buffer such that, after the plurality of time intervals, some or all of a background reference frame is stored in the buffer; receiving an encoded updated portion of the background reference frame; decoding the updated portion to produce a decoded updated portion; and overwriting the corresponding portion of the background reference frame in the buffer using the decoded updated portion in response to determining, at the video decoder, that the updated portion is of superior quality relative to the corresponding portion of the background reference frame in the buffer, characterised in that the determination is made using a quality parameter.