A fixation device for fixing a medical line to a patient, in particular an endotracheal tube, comprising a retainer and a support member for supporting the retainer on the patient, the retainer defining an axis and being adapted to retain the line extending in axial direction, wherein the retainer is openable and closable, in an open state accepting the line to be clamped in another direction than axial direction, and in a closed state configured for clamping the line; wherein the retainer comprises an enclosure for radially retaining the line and a clamp accommodated at least partly within the enclosure,wherein the clamp comprises a deformable clamp member, characterised in that the deformable clamp member comprises one of a flexible strap, belt or chain, that the clamp comprises a second clamp member which is adjustably coupled together with the deformable clamp member via a clamp connector, wherein the second clamp member and the clamp connector comprise, respectively, teeth and a pawl forming a ratchet-and-pawl connection for tightening the clamp in the circumferential direction around the axis, so that an opening of the clamp accommodating the line is reduced and the clamp is configured to provide a crimping force around the axis for fixing the line in at least axial direction relative to the enclosure, preferably also in radial direction. a retainer and a support member for supporting the retainer on the patient, the retainer defining an axis and being adapted to retain the line extending in axial direction, wherein the retainer is openable and closable, in an open state accepting the line to be clamped in another direction than axial direction, and in a closed state configured for clamping the line; wherein the retainer comprises an enclosure for radially retaining the line and a clamp accommodated at least partly within the enclosure,wherein the clamp comprises a deformable clamp member, characterised in that the deformable clamp member comprises one of a flexible strap, belt or chain, that the clamp comprises a second clamp member which is adjustably coupled together with the deformable clamp member via a clamp connector, wherein the second clamp member and the clamp connector comprise, respectively, teeth and a pawl forming a ratchet-and-pawl connection for tightening the clamp in the circumferential direction around the axis, so that an opening of the clamp accommodating the line is reduced and the clamp is configured to provide a crimping force around the axis for fixing the line in at least axial direction relative to the enclosure, preferably also in radial direction. wherein the retainer comprises an enclosure for radially retaining the line and a clamp accommodated at least partly within the enclosure,wherein the clamp comprises a deformable clamp member, characterised in that the deformable clamp member comprises one of a flexible strap, belt or chain, that the clamp comprises a second clamp member which is adjustably coupled together with the deformable clamp member via a clamp connector, wherein the second clamp member and the clamp connector comprise, respectively, teeth and a pawl forming a ratchet-and-pawl connection for tightening the clamp in the circumferential direction around the axis, so that an opening of the clamp accommodating the line is reduced and the clamp is configured to provide a crimping force around the axis for fixing the line in at least axial direction relative to the enclosure, preferably also in radial direction.