A bio sample collection device comprising: - a housing; - a cap part detachably fastened to the housing, and including a bio sample collector for collecting a bio sample; and - a bio sample processing liquid storage unit storing bio sample processing liquid, wherein the cap part and the housing have screw threads corresponding to each other, so that the cap part is configured to be detachable by rotation to the housing, - a stopper is formed on the screw thread of the cap part and the housing, and the cap part and the housing are configured to be fastened only to the stopper before the bio sample is collected, and - the cap part and the housing are configured to be completely fastened to each other through the stopper, after the bio sample is collected by the bio sample collector; wherein the cap part comprises: - a covering part formed with the screw thread and configured to be fastened to the housing; and - a cylinder part having an upper portion connected to a lower portion of the covering part and having a lower portion opened, wherein the bio sample collector is configured to be movably combined with the cylinder part, so that the bio sample collector is configured to be movable along the outer surface of the cylinder part up and down; wherein the bio sample collector comprises a plurality of protruding parts protruding toward a bottom of the housing; characterized in that the lower portion of the cylinder part, which is open, is sealed by a sealing film, so that the bio sample processing liquid is contained in the cylinder part to configure the bio sample processing liquid storage unit; and wherein the bio sample collector comprises a puncher, so that the puncher is configured to punch the sealing film when the cap part and the housing are completely engaged, thereby introducing the bio sample processing liquid into the housing. - a housing; - a cap part detachably fastened to the housing, and including a bio sample collector for collecting a bio sample; and - a bio sample processing liquid storage unit storing bio sample processing liquid, wherein the cap part and the housing have screw threads corresponding to each other, so that the cap part is configured to be detachable by rotation to the housing, - a stopper is formed on the screw thread of the cap part and the housing, and the cap part and the housing are configured to be fastened only to the stopper before the bio sample is collected, and - the cap part and the housing are configured to be completely fastened to each other through the stopper, after the bio sample is collected by the bio sample collector; - a stopper is formed on the screw thread of the cap part and the housing, and the cap part and the housing are configured to be fastened only to the stopper before the bio sample is collected, and - the cap part and the housing are configured to be completely fastened to each other through the stopper, after the bio sample is collected by the bio sample collector; wherein the cap part comprises: - a covering part formed with the screw thread and configured to be fastened to the housing; and - a cylinder part having an upper portion connected to a lower portion of the covering part and having a lower portion opened, wherein the bio sample collector is configured to be movably combined with the cylinder part, so that the bio sample collector is configured to be movable along the outer surface of the cylinder part up and down; wherein the bio sample collector comprises a plurality of protruding parts protruding toward a bottom of the housing; characterized in that the lower portion of the cylinder part, which is open, is sealed by a sealing film, so that the bio sample processing liquid is contained in the cylinder part to configure the bio sample processing liquid storage unit; and wherein the bio sample collector comprises a puncher, so that the puncher is configured to punch the sealing film when the cap part and the housing are completely engaged, thereby introducing the bio sample processing liquid into the housing. - a covering part formed with the screw thread and configured to be fastened to the housing; and - a cylinder part having an upper portion connected to a lower portion of the covering part and having a lower portion opened, wherein the bio sample collector is configured to be movably combined with the cylinder part, so that the bio sample collector is configured to be movable along the outer surface of the cylinder part up and down; wherein the bio sample collector comprises a plurality of protruding parts protruding toward a bottom of the housing; characterized in that the lower portion of the cylinder part, which is open, is sealed by a sealing film, so that the bio sample processing liquid is contained in the cylinder part to configure the bio sample processing liquid storage unit; and wherein the bio sample collector comprises a puncher, so that the puncher is configured to punch the sealing film when the cap part and the housing are completely engaged, thereby introducing the bio sample processing liquid into the housing.