A compound or salt thereof of the formula: Wherein: R 1 is H or -C R 4, R 4 is hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl, aryl, alkyaryl, arylakyl, arylalkenyl, arylalkynyl and heterocyclic; R 3 is hydrogen, R 2 is substituted alkyl having in the range of 1 up to 8 carbon atoms, where substituent is -NR 7 R 8, and its pharmaceutically acceptable salts formed with inorganic and/or organic acid, and including its quaternary ammonium salts formed with R 9 Z; Where R 7 and R 8 are selected from hydrogen, alkyl having in the range of 1 up to 8 carbon atoms, or cycloalkyl; Z is fluorine, chlorine, bromine, iodine, tosylate, methanesulfonate, benzenesulfonate, trifluoromethanesulfonate, R 9 is alkyl, cycloalkyl, alkyl substituted by hydroxyl,alkenyl, alkynyl, aryl, heterocyclic, arylakyl, arylalkenyl, arylalkynyl, cyanomethyl, alkoxy or aryloxyalkyl; inorganic or organic acid are hydrofluoric acid, hydrochloric acid, hydrobromic acid, hydriodic acid, sulfuric acid, nitric acid, phosphoric acid, carbonic acid, boric acid, selenious acid, phosphomolybdic acid, phosphorous acid, sulfurous acid, citric acid, maleic acid, D-malic acid, L-malic acid, DL-malic acid, L-lactic acid, D-lactic acid, DL-lactic acid, oxalic acid, methanesulfonic acid, valeric acid, oleic acid, lauric acid, para-toluenesulfonic acid, 1-naphthalensulfonic acid, 2-naphthalensulfonic acid, phthalic acid, tartaric acid, malonic acid, succinic acid, fumaric acid, glycolic acid, thioglycolic acid, glycine, sarcocine, sulfonic acid, nicotinic acid, picolinic acid, isonicotinic acid, and benzoic acid; X is O; Y is single bond, O, R 11 N, R 12 R 13 C, R 11 is hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl, aryl, alkyaryl, arylalkyl, arylalkenyl, arylalkynyl or heterocyclic; R 12 and R 13 are the same or different, they are hydrogen, fluorine, chlorine, bromine, iodine, alkyl, cycloalkyl, alkyl substituted by hydroxyl,alkenyl, alkynyl, aryl, heterocyclic, arylakyl, arylalkenyl, arylalkynyl, cyanomethyl, alkoxy or aryloxyalkyl. R 1 is H or -C R 4, R 4 is hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl, aryl, alkyaryl, arylakyl, arylalkenyl, arylalkynyl and heterocyclic; R 3 is hydrogen, R 2 is substituted alkyl having in the range of 1 up to 8 carbon atoms, where substituent is -NR 7 R 8, and its pharmaceutically acceptable salts formed with inorganic and/or organic acid, and including its quaternary ammonium salts formed with R 9 Z; Where R 7 and R 8 are selected from hydrogen, alkyl having in the range of 1 up to 8 carbon atoms, or cycloalkyl; Z is fluorine, chlorine, bromine, iodine, tosylate, methanesulfonate, benzenesulfonate, trifluoromethanesulfonate, R 9 is alkyl, cycloalkyl, alkyl substituted by hydroxyl,alkenyl, alkynyl, aryl, heterocyclic, arylakyl, arylalkenyl, arylalkynyl, cyanomethyl, alkoxy or aryloxyalkyl; inorganic or organic acid are hydrofluoric acid, hydrochloric acid, hydrobromic acid, hydriodic acid, sulfuric acid, nitric acid, phosphoric acid, carbonic acid, boric acid, selenious acid, phosphomolybdic acid, phosphorous acid, sulfurous acid, citric acid, maleic acid, D-malic acid, L-malic acid, DL-malic acid, L-lactic acid, D-lactic acid, DL-lactic acid, oxalic acid, methanesulfonic acid, valeric acid, oleic acid, lauric acid, para-toluenesulfonic acid, 1-naphthalensulfonic acid, 2-naphthalensulfonic acid, phthalic acid, tartaric acid, malonic acid, succinic acid, fumaric acid, glycolic acid, thioglycolic acid, glycine, sarcocine, sulfonic acid, nicotinic acid, picolinic acid, isonicotinic acid, and benzoic acid; X is O; Y is single bond, O, R 11 N, R 12 R 13 C, R 11 is hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl, aryl, alkyaryl, arylalkyl, arylalkenyl, arylalkynyl or heterocyclic; R 12 and R 13 are the same or different, they are hydrogen, fluorine, chlorine, bromine, iodine, alkyl, cycloalkyl, alkyl substituted by hydroxyl,alkenyl, alkynyl, aryl, heterocyclic, arylakyl, arylalkenyl, arylalkynyl, cyanomethyl, alkoxy or aryloxyalkyl.