mhurhangee/ep-ind-claims huggingface dataset:
A method of detecting cancer cells in vitro, comprising the following steps: (a) a step of bringing a composition containing an L-glucose or an L-glucose in which a hydroxyl group is substituted by an amino group or a fluorine atom, said L-glucose being linked to a 7-nitrobenz-2-oxa-1,3-diazole group or a 7-(N,N-dimethylaminosulfonyl)benz-2-oxa-1,3-diazole group via an amine or via a spacer represented by the formula -NH-(CH 2) n -NH-, in which formula n is 2 to 20, or a salt form thereof into contact with a target cell in vitro, (b) a step of detecting the L-glucose linked to the 7-nitrobenz-2-oxa-1,3-diazole group or 7-(N,N-dimethylaminosulfonyl)benz-2-oxa-1,3-diazole group present in the target cell by detecting fluorescence, and (c) a step of detecting a cancer cell based on an increase in the fluorescence intensity in the target cell. (a) a step of bringing a composition containing an L-glucose or an L-glucose in which a hydroxyl group is substituted by an amino group or a fluorine atom, said L-glucose being linked to a 7-nitrobenz-2-oxa-1,3-diazole group or a 7-(N,N-dimethylaminosulfonyl)benz-2-oxa-1,3-diazole group via an amine or via a spacer represented by the formula -NH-(CH 2) n -NH-, in which formula n is 2 to 20, or a salt form thereof into contact with a target cell in vitro, (b) a step of detecting the L-glucose linked to the 7-nitrobenz-2-oxa-1,3-diazole group or 7-(N,N-dimethylaminosulfonyl)benz-2-oxa-1,3-diazole group present in the target cell by detecting fluorescence, and (c) a step of detecting a cancer cell based on an increase in the fluorescence intensity in the target cell.
System for transforming plastic parisons to plastic containers with a transport device which transports the plastic parisons along a predetermined transport path, wherein the transport device has a movable station support arranged at least indirectly on a stationary base support on which a plurality of transforming stations is arranged, wherein these transforming stations each have blow mould devices which each form cavities within which the plastic parisons can be transformed into the plastic containers and these blow mould devices are each arranged on blow mould supports, wherein the system has a manual changing device which is suitable and intended to, in a changing mode of the system, at least to remove the blow mould devices from their blow mould supports and/or to arrange blow mould devices on the blow mould supports, characterized in that during a further mode of operation which differs from the changing mode, the changing device is further suitable and intended for carrying out a treatment operation on at least one working element intended for the system, and further wherein the manual changing device is a manipulator, wherein the manipulator is suitable and intended to compensate a dead weight of the blow mould devices to be moved, wherein a gripping device for gripping the blow moulds to be moved is attached to one end of the manual changing device, the manual changing device is suitable and intended to be guided by an operator, the manual changing device is suitable and intended to exchange the blow mould device as a mould package, i.e. in particular including all parts of the blow mould, and further and wherein the gripping device is movable in at least two different directions. during a further mode of operation which differs from the changing mode, the changing device is further suitable and intended for carrying out a treatment operation on at least one working element intended for the system, and further wherein the manual changing device is a manipulator, wherein the manipulator is suitable and intended to compensate a dead weight of the blow mould devices to be moved, wherein a gripping device for gripping the blow moulds to be moved is attached to one end of the manual changing device, the manual changing device is suitable and intended to be guided by an operator, the manual changing device is suitable and intended to exchange the blow mould device as a mould package, i.e. in particular including all parts of the blow mould, and further and wherein the gripping device is movable in at least two different directions.
An improved method of plugging a well, wherein said method comprises removing inner tubing and outer casing at a section of a well to be plugged, and setting a base plug and a plug in said section, said improved method comprising: removing an inner tubing string before an outer casing is cut; cutting a plurality of helical coil openings at different depths through said outer casing at said section instead of removing said outer casing; deploying a solid bismuth alloy plug material below and adjacent to said helical coil openings; deploying a heater to said helical coil openings to melt said bismuth alloy plug material wherein said melted bismuth alloy plug material flows out of said helical coil openings and fills a portion of said section and cools to form a bismuth alloy plug; deploying a plugging material downhole adjacent said base plug; squeezing said plugging material out of said helical coil openings; and allowing said plugging material to set and form a plug, such that said set plugging material and said bismuth alloy plug together form multiple O-ring type rock-to-rock seals at different depths through said plurality of helical coil openings. removing an inner tubing string before an outer casing is cut; cutting a plurality of helical coil openings at different depths through said outer casing at said section instead of removing said outer casing; deploying a solid bismuth alloy plug material below and adjacent to said helical coil openings; deploying a heater to said helical coil openings to melt said bismuth alloy plug material wherein said melted bismuth alloy plug material flows out of said helical coil openings and fills a portion of said section and cools to form a bismuth alloy plug; deploying a plugging material downhole adjacent said base plug; squeezing said plugging material out of said helical coil openings; and allowing said plugging material to set and form a plug, such that said set plugging material and said bismuth alloy plug together form multiple O-ring type rock-to-rock seals at different depths through said plurality of helical coil openings.
A computer device (102; 710) for use in material processing of a two dimensional sheet like material, the computer device (102; 710) comprising: means adapted to obtain information related to a desired design of a three dimensional object, means adapted to obtain information related to material characteristics of the two dimensional sheet like material, means adapted to define a primary surface and a secondary surface of the desired design of the three dimensional object, and means adapted to define a geometrical relationship between said primary surface and secondary surface, wherein the secondary surface is a reflection of the primary surface in a two dimensional plane, and wherein when said primary surface is concave said secondary surface is convex, or when said primary surface is convex said secondary surface is concave; and means adapted to provide, or otherwise create, a digital instruction for a fully developed spreading and subsequent folding of a two dimensional sheet into the obtained desired design of the three dimensional object, wherein said digital instruction is based on the defined primary and secondary surfaces, respectively, and said obtained material characteristics. means adapted to obtain information related to a desired design of a three dimensional object, means adapted to obtain information related to material characteristics of the two dimensional sheet like material, means adapted to define a primary surface and a secondary surface of the desired design of the three dimensional object, and means adapted to define a geometrical relationship between said primary surface and secondary surface, wherein the secondary surface is a reflection of the primary surface in a two dimensional plane, and wherein when said primary surface is concave said secondary surface is convex, or when said primary surface is convex said secondary surface is concave; and the secondary surface is a reflection of the primary surface in a two dimensional plane, and wherein when said primary surface is concave said secondary surface is convex, or when said primary surface is convex said secondary surface is concave; and means adapted to provide, or otherwise create, a digital instruction for a fully developed spreading and subsequent folding of a two dimensional sheet into the obtained desired design of the three dimensional object, wherein said digital instruction is based on the defined primary and secondary surfaces, respectively, and said obtained material characteristics.
A compound, or salt thereof, which compound is represented by Formula wherein A' is selected from: B is selected from wherein Z is NH or N(Me); or B is selected from A' is selected from: B is selected from wherein Z is NH or N(Me); or B is selected from
A method for manufacturing coal briquettes charged into a dome part of the melter-gasifier to be rapidly heated in an apparatus for manufacturing molten iron, the method comprising: providing fine coal; preparing a mixture by mixing a hardening agent of 1 to 5 parts by weight and a binder of 5 to 15 parts by weight with respect to fine coals of 100 parts by weight; and molding the mixture; characterized in that in the providing of the fine coal, the fine coals comprise low-grade coal of more than 0 and 50wt% or less and metallurgical coal, and the low-grade coal has a volatile matter (on a dry basis) of 25wt% to 40wt% and a free swelling index of more than 0 and less than 3. providing fine coal; preparing a mixture by mixing a hardening agent of 1 to 5 parts by weight and a binder of 5 to 15 parts by weight with respect to fine coals of 100 parts by weight; and molding the mixture; characterized in that in the providing of the fine coal, the fine coals comprise low-grade coal of more than 0 and 50wt% or less and metallurgical coal, and the low-grade coal has a volatile matter (on a dry basis) of 25wt% to 40wt% and a free swelling index of more than 0 and less than 3.
A lubricating oil composition not containing ZnDTP but comprising the following components (a) to (c): (a) a base oil; (b) molybdenum dialkyldithiocarbamate; and (c) an organic acid metal salt compound which is cobalt 2-ethylhexanoate or nickel 2-ethylhexanoate. (a) a base oil; (b) molybdenum dialkyldithiocarbamate; and (c) an organic acid metal salt compound which is cobalt 2-ethylhexanoate or nickel 2-ethylhexanoate.
A method of controlling the temperature of an environment, such as a flooring surface, comprising the steps of: providing a thermostat adapted to have values in the memory of a microprocessor assigned for each discrete time period for a 24 hour time period; receiving a signal from an occupancy sensor in a first area indicating whether the first area has been occupied for each discrete time period of a 24 hour time period; characterized in that it further comprises the steps of assigning a first point value to each discrete time period where occupancy has been sensed during each discrete time period in a first 24 hour time period; assigning a second point value to each discrete time period where occupancy has been sensed during each discrete time period in a second 24 hour time period that predates the first 24 hour time period; assigning a third point value to each discrete time period where occupancy has been sensed during each discrete time period in a third 24 hour time period that predates the second time period; averaging the point values for each discrete time period in the first, second, and third 24 hour periods, where occupancy was sensed in any of the first, second, or third 24 hour periods to obtain an average point value; sending a first signal to a heating device adapted for heating a second area to provide a temperature-related setting for a given discrete time period when the average point value for the given discrete time period is above a threshold point value K. providing a thermostat adapted to have values in the memory of a microprocessor assigned for each discrete time period for a 24 hour time period; receiving a signal from an occupancy sensor in a first area indicating whether the first area has been occupied for each discrete time period of a 24 hour time period; characterized in that it further comprises the steps of assigning a first point value to each discrete time period where occupancy has been sensed during each discrete time period in a first 24 hour time period; assigning a second point value to each discrete time period where occupancy has been sensed during each discrete time period in a second 24 hour time period that predates the first 24 hour time period; assigning a third point value to each discrete time period where occupancy has been sensed during each discrete time period in a third 24 hour time period that predates the second time period; averaging the point values for each discrete time period in the first, second, and third 24 hour periods, where occupancy was sensed in any of the first, second, or third 24 hour periods to obtain an average point value; sending a first signal to a heating device adapted for heating a second area to provide a temperature-related setting for a given discrete time period when the average point value for the given discrete time period is above a threshold point value K.
A measuring arrangement of a wind power installation having a tower and an aerodynamic rotor with at least one rotor blade for determining a thrust force of the rotor, comprising: - a measuring device configured for detecting a first bending moment of the tower at a first height and a second bending moment of the tower at a second height, which is different from the first height, the first and second bending moments (B1, B2) being made up in each case of a natural moment component, a pitching moment component and a thrust force moment component, - a thrust force determining unit configured for determining a thrust force based on a first comparison value, determined on the basis of a comparison of the first and second bending moments (B1, B2), the first comparison value being independent of the natural moment component and the pitching moment component. - a measuring device configured for detecting a first bending moment of the tower at a first height and a second bending moment of the tower at a second height, which is different from the first height, the first and second bending moments (B1, B2) being made up in each case of a natural moment component, a pitching moment component and a thrust force moment component, - a thrust force determining unit configured for determining a thrust force based on a first comparison value, determined on the basis of a comparison of the first and second bending moments (B1, B2), the first comparison value being independent of the natural moment component and the pitching moment component.
A flexible multiple chamber bag made by circumferentially welding two foils being non peelable and furthermore containing peelable and non-peelable welds (4,5,6) within the circumference weld for the separate storing of medical products in separate chambers (1,2,3), containing a hanger flap extending from the top end of said bag and a single medical port system welded within the lower end of said circumferential weld of said bag characterized in that one side end being different from the top end and the lower end of said circumferential weld of said bag contains a number of non-welded frustoconical-shaped interruptions (12,13,14) between said foils, each of said interruptions (12,13,14) respectively being connected to a different chamber (1 or 2 or 3) allowing the temporarily or permanent introduction of an appropriate filling tube (22,23,24) into each of said interruptions (12,13,14) wherein the opening angle from the inner side of the weld to the outer side of the weld of said frustoconical interruptions (12,13,14) is adjusted by welding and encompasses a solid angle of 15° to 60°.
A device for use in removing adipose tissue from a surgical site, the device comprising: a removable coupler (108, 140, 308, 408) configured to be connected to a cannula (102, 402) so that a channel of the cannula (102, 402) and a channel (130, 430) of the removable coupler (108, 140, 308, 408) provide a pathway for flow of adipose tissue from the surgical site, the removable coupler (108, 140, 308, 408) including a distal end and a cavity (136, 142, 436) located in the distal end and having interior walls, and a motor (106, 306) connected to the removable coupler (108, 140, 308, 408), the motor (106, 306) configured to rotate the cannula (102, 402), wherein a center axis of the motor (106, 306) is adjacent a center axis of the removable coupler (108, 140, 308, 408) so that the pathway does not pass through the motor (106, 306), characterized in that the removable coupler (108, 140, 308, 408) includes a plurality of venting channels on the interior walls of the cavity (136, 142, 436) and that allow a certain amount of air to flow between the interior walls of the cavity (136, 142, 436) and the cannula (102, 402). a removable coupler (108, 140, 308, 408) configured to be connected to a cannula (102, 402) so that a channel of the cannula (102, 402) and a channel (130, 430) of the removable coupler (108, 140, 308, 408) provide a pathway for flow of adipose tissue from the surgical site, the removable coupler (108, 140, 308, 408) including a distal end and a cavity (136, 142, 436) located in the distal end and having interior walls, and a motor (106, 306) connected to the removable coupler (108, 140, 308, 408), the motor (106, 306) configured to rotate the cannula (102, 402), wherein a center axis of the motor (106, 306) is adjacent a center axis of the removable coupler (108, 140, 308, 408) so that the pathway does not pass through the motor (106, 306), characterized in that the removable coupler (108, 140, 308, 408) includes a plurality of venting channels on the interior walls of the cavity (136, 142, 436) and that allow a certain amount of air to flow between the interior walls of the cavity (136, 142, 436) and the cannula (102, 402).
A wash-down toilet comprising: a bowl having a sump; a passageway having an inlet, an outlet provided at a height above the inlet, and a weir, the inlet being in fluid communication with the sump; and a trapway including a body extending between an inlet and an outlet of the trapway wherein the inlet of the trapway is in fluid communication with the outlet of the passageway, and the outlet of the trapway is configured to be in fluid communication with a soil pipe, characterized in that: the trapway includes a first vent and a second vent, one of the first and second vents is configured as a one-way vent that allows fluid, such as air, to enter the body portion of the trapway from the first vent, and the second vent is configured as a one-way vent that allows gases to exit the body portion into the second vent, said first vent comprises a valve to supply air from an air supply to the trapway to prevent siphoning of the toilet and to prevent the fluid flowing through the trapway from entering the first vent from the trapway, and said second vent comprises a valve, said valve enabling gases to escape from the body portion and preventing fluid from entering the second vent from the body of the trapway. a bowl having a sump; a passageway having an inlet, an outlet provided at a height above the inlet, and a weir, the inlet being in fluid communication with the sump; and a trapway including a body extending between an inlet and an outlet of the trapway wherein the inlet of the trapway is in fluid communication with the outlet of the passageway, and the outlet of the trapway is configured to be in fluid communication with a soil pipe, characterized in that: the trapway includes a first vent and a second vent, one of the first and second vents is configured as a one-way vent that allows fluid, such as air, to enter the body portion of the trapway from the first vent, and the second vent is configured as a one-way vent that allows gases to exit the body portion into the second vent, said first vent comprises a valve to supply air from an air supply to the trapway to prevent siphoning of the toilet and to prevent the fluid flowing through the trapway from entering the first vent from the trapway, and said second vent comprises a valve, said valve enabling gases to escape from the body portion and preventing fluid from entering the second vent from the body of the trapway.
Naked mRNA, optionally complexed by a (poly)cationic polymer, polyplexes, protein(s) or peptide(s), for use in the treatment of cancer diseases, cardiovascular diseases, infectious diseases or autoimmune diseases, wherein - the mRNA is suitable for intracellular expression of an antibody and - contains at least one coding region, wherein the at least one coding region codes for at least one antibody comprising a light chain and a heavy chain, both of which having variable and constant domains. - the mRNA is suitable for intracellular expression of an antibody and - contains at least one coding region, wherein the at least one coding region codes for at least one antibody comprising a light chain and a heavy chain, both of which having variable and constant domains.
A method for hydrodynamically eliminating defects in the interior of pipelines, in particular for sanifying and cleaning water-carrying pipelines in the domestic and industrial sector, wherein a pressure jet acting on the defect is generated with the aid of a pressure jet nozzle having a central outlet opening supplied with working fluid via a pressure hose, while the pressure jet nozzle is moved relative to the pipeline, having the following method steps: a) connecting the pressure jet nozzle to a tension and compression resistant push rod, b) inserting the pressure jet nozzle into the pipeline with the aid of the push rod up to the defect, c) further pushing or withdrawing the pressure jet nozzle until a predetermined distance to the defect is reached, wherein the pressure jet nozzle points to the defect, d) generating a pressure jet in the form of a rotating spot jet only in the direction of the defect having a jet angle at which the pressure jet generated leaves the front, central outlet opening in relation to the longitudinal axis of the pressure jet nozzle, between 15° and 45° in the case of an operating pressure of up to 600 bar and greater, e) generating a movement of the pressure jet nozzle in the direction of the defect. a) connecting the pressure jet nozzle to a tension and compression resistant push rod, b) inserting the pressure jet nozzle into the pipeline with the aid of the push rod up to the defect, c) further pushing or withdrawing the pressure jet nozzle until a predetermined distance to the defect is reached, wherein the pressure jet nozzle points to the defect, d) generating a pressure jet in the form of a rotating spot jet only in the direction of the defect having a jet angle at which the pressure jet generated leaves the front, central outlet opening in relation to the longitudinal axis of the pressure jet nozzle, between 15° and 45° in the case of an operating pressure of up to 600 bar and greater, e) generating a movement of the pressure jet nozzle in the direction of the defect.