A method for synthesizing a 2-((6-(hydroxymethyl)chromen-5-yl)oxy)-1-phenylethanone derivative represented by Formula 4, the method comprising steps of: (a) reducing a compound of Formula 1 to produce a compound of Formula 2; and (b) coupling the compound of Formula 2 with a compound of Formula 3: wherein the dotted line is an optional double bond; R 1 and R 2 are each independently any one of a hydrogen atom; a substituted or unsubstituted linear or branched C 1 -C 6 alkyl group; a halogen atom; a substituted or unsubstituted linear or branched C 1 -C 6 alkoxy group; a substituted or unsubstituted linear or branched C 1 -C 4 thioalkyl group; a substituted or unsubstituted allyloxy group; a substituted or unsubstituted aryloxy group; and a phenyl group; R 3 is any one of a hydrogen atom; a C 1 -C 3 alkyl group; a C 1 -C 3 alkoxy group; and a halogen atom; R 4 and R 5 are each independently any one of a hydrogen atom and a C 1 -C 2 alkyl group; P is any one of a substituted or unsubstituted linear or branched C 1 -C 4 alkyl group; a substituted or unsubstituted benzyl group; an allyl group; a t-butyldimethylsilyl group; t-butyldiphenylsilyl group; a dimethylphenylsilyl group; a trimethylsilyl group; MeSO 2, a p-toluenesulfonyl group; and a 2,4,6-trimethylbenzenesulfonyl group; n is from 1 to 3; when OP is plural in number, they are the same or different; and the substituent for the substituted alkyl group, substituted alkoxy group, substituted thioalkyl group, substituted allyloxy group, substituted aryloxy group or substituted benzyl group is any one of a benzyloxy group, a halogen atom, a linear or branched C 1 -C 5 alkyl group, a linear or branched C 1 -C 5 alkoxy group, a linear or branched C 1 -C 3 thioalkyl group, a nitro group, and a naphthalene group. (a) reducing a compound of Formula 1 to produce a compound of Formula 2; and (b) coupling the compound of Formula 2 with a compound of Formula 3: wherein the dotted line is an optional double bond; R 1 and R 2 are each independently any one of a hydrogen atom; a substituted or unsubstituted linear or branched C 1 -C 6 alkyl group; a halogen atom; a substituted or unsubstituted linear or branched C 1 -C 6 alkoxy group; a substituted or unsubstituted linear or branched C 1 -C 4 thioalkyl group; a substituted or unsubstituted allyloxy group; a substituted or unsubstituted aryloxy group; and a phenyl group; R 3 is any one of a hydrogen atom; a C 1 -C 3 alkyl group; a C 1 -C 3 alkoxy group; and a halogen atom; R 4 and R 5 are each independently any one of a hydrogen atom and a C 1 -C 2 alkyl group; P is any one of a substituted or unsubstituted linear or branched C 1 -C 4 alkyl group; a substituted or unsubstituted benzyl group; an allyl group; a t-butyldimethylsilyl group; t-butyldiphenylsilyl group; a dimethylphenylsilyl group; a trimethylsilyl group; MeSO 2, a p-toluenesulfonyl group; and a 2,4,6-trimethylbenzenesulfonyl group; n is from 1 to 3; when OP is plural in number, they are the same or different; and the substituent for the substituted alkyl group, substituted alkoxy group, substituted thioalkyl group, substituted allyloxy group, substituted aryloxy group or substituted benzyl group is any one of a benzyloxy group, a halogen atom, a linear or branched C 1 -C 5 alkyl group, a linear or branched C 1 -C 5 alkoxy group, a linear or branched C 1 -C 3 thioalkyl group, a nitro group, and a naphthalene group. the dotted line is an optional double bond; R 1 and R 2 are each independently any one of a hydrogen atom; a substituted or unsubstituted linear or branched C 1 -C 6 alkyl group; a halogen atom; a substituted or unsubstituted linear or branched C 1 -C 6 alkoxy group; a substituted or unsubstituted linear or branched C 1 -C 4 thioalkyl group; a substituted or unsubstituted allyloxy group; a substituted or unsubstituted aryloxy group; and a phenyl group; R 3 is any one of a hydrogen atom; a C 1 -C 3 alkyl group; a C 1 -C 3 alkoxy group; and a halogen atom; R 4 and R 5 are each independently any one of a hydrogen atom and a C 1 -C 2 alkyl group; P is any one of a substituted or unsubstituted linear or branched C 1 -C 4 alkyl group; a substituted or unsubstituted benzyl group; an allyl group; a t-butyldimethylsilyl group; t-butyldiphenylsilyl group; a dimethylphenylsilyl group; a trimethylsilyl group; MeSO 2, a p-toluenesulfonyl group; and a 2,4,6-trimethylbenzenesulfonyl group; n is from 1 to 3; when OP is plural in number, they are the same or different; and the substituent for the substituted alkyl group, substituted alkoxy group, substituted thioalkyl group, substituted allyloxy group, substituted aryloxy group or substituted benzyl group is any one of a benzyloxy group, a halogen atom, a linear or branched C 1 -C 5 alkyl group, a linear or branched C 1 -C 5 alkoxy group, a linear or branched C 1 -C 3 thioalkyl group, a nitro group, and a naphthalene group.