A device for collecting a breath portion from a patient for analysis, comprising: a housing structure including: an inlet port for receiving a portion of the patient's breath; at least one sensor operatively coupled to the inlet port for detecting one or more parameters regarding the patient's breath; and wherein the device is portable and the inlet port includes a mask structure configured to conform to the patient's face and further comprises at least one sorbent tube for collecting a portion of the patient's breath received in the inlet port and configured to be detachable from the housing structure, the at least one sorbent tube pushed through holes formed in the mask structure and connected into a device frame; at least one pump configured to draw the patient's breath from the inlet port through the at least one sorbent tube and facilitating both passage of the patient's breath through the at least one sorbent tube and capture of a portion of the patient's breath in the at least one sorbent tube; and a control system for controlling operation of the at least one sensor and at least one pump and which selectively operates the at least one pump based upon a pressure level of the patient's breath as detected by the at least one sensor. a housing structure including: an inlet port for receiving a portion of the patient's breath; at least one sensor operatively coupled to the inlet port for detecting one or more parameters regarding the patient's breath; and wherein the device is portable and the inlet port includes a mask structure configured to conform to the patient's face and further comprises at least one sorbent tube for collecting a portion of the patient's breath received in the inlet port and configured to be detachable from the housing structure, the at least one sorbent tube pushed through holes formed in the mask structure and connected into a device frame; at least one pump configured to draw the patient's breath from the inlet port through the at least one sorbent tube and facilitating both passage of the patient's breath through the at least one sorbent tube and capture of a portion of the patient's breath in the at least one sorbent tube; and a control system for controlling operation of the at least one sensor and at least one pump and which selectively operates the at least one pump based upon a pressure level of the patient's breath as detected by the at least one sensor. an inlet port for receiving a portion of the patient's breath; at least one sensor operatively coupled to the inlet port for detecting one or more parameters regarding the patient's breath; and wherein the device is portable and the inlet port includes a mask structure configured to conform to the patient's face and further comprises at least one sorbent tube for collecting a portion of the patient's breath received in the inlet port and configured to be detachable from the housing structure, the at least one sorbent tube pushed through holes formed in the mask structure and connected into a device frame; at least one pump configured to draw the patient's breath from the inlet port through the at least one sorbent tube and facilitating both passage of the patient's breath through the at least one sorbent tube and capture of a portion of the patient's breath in the at least one sorbent tube; and a control system for controlling operation of the at least one sensor and at least one pump and which selectively operates the at least one pump based upon a pressure level of the patient's breath as detected by the at least one sensor.