mhurhangee/ep-ind-claims huggingface dataset:
A method for producing tumor-targeting virus-like particles, comprising: (a) transiently transfecting cells with a nucleic acid that encodes one or more papilloma virus capsid proteins, thereby forming proto-capsids, (b) collecting the proto-capsids and subjecting the proto-capsids to a maturation process in vitro, thereby forming virus-like particles, and (c) chemically conjugating photosensitive molecules to papilloma virus capsid proteins of the virus-like particles, wherein each virus-like particle is conjugated to about 50 to 1000 photosensitive molecules, and wherein cytotoxicity of the photosensitive molecules is activated by exposure to infrared, near-infrared or ultraviolet light. (a) transiently transfecting cells with a nucleic acid that encodes one or more papilloma virus capsid proteins, thereby forming proto-capsids, (b) collecting the proto-capsids and subjecting the proto-capsids to a maturation process in vitro, thereby forming virus-like particles, and (c) chemically conjugating photosensitive molecules to papilloma virus capsid proteins of the virus-like particles, wherein each virus-like particle is conjugated to about 50 to 1000 photosensitive molecules, and wherein cytotoxicity of the photosensitive molecules is activated by exposure to infrared, near-infrared or ultraviolet light.
A liquid antimicrobial composition for use in the disinfection of the skin of a human or an animal in the form of an aqueous or aqueous alcohol solution or dispersion and comprising a cationic, cell membrane-disrupting biocide being chlorhexidine in the form of a gluconate or of an acetate salt that is present in a concentration between 0.25% and 6.00% w/v inclusive, a cationic dendrimer capable of inhibiting an efflux pump mechanism of said cell membrane and being a generation 1 polyamidoamine (PAMAM) dendrimer, wherein the dendrimer comprises between 0.01% w/v and 2% w/v inclusive of the composition, additionally comprising a surfactant, wherein the surfactant is a poloxamer tri block copolymer surfactant and wherein non-medical use is excluded. a cationic, cell membrane-disrupting biocide being chlorhexidine in the form of a gluconate or of an acetate salt that is present in a concentration between 0.25% and 6.00% w/v inclusive, a cationic dendrimer capable of inhibiting an efflux pump mechanism of said cell membrane and being a generation 1 polyamidoamine (PAMAM) dendrimer, wherein the dendrimer comprises between 0.01% w/v and 2% w/v inclusive of the composition, additionally comprising a surfactant, wherein the surfactant is a poloxamer tri block copolymer surfactant and wherein non-medical use is excluded.
Device comprising a work table having a work plate that comprises a receiving opening for stationary operation of a machine-driven tool, comprising an insert plate which can be inserted into the receiving opening and comprises, on the mounting face thereof which faces downwards when inserted, attaching means for attaching a drive machine and a tool passage opening through which a tool, which is drivable by the drive machine, projects beyond the work face which faces upwards when clamped, the insert plate having a surface profile on the work face thereof for mobile operation of the machine-driven tool, which surface profile corresponds to a guide profile of a guide rail such that the drive machine attached to the mounting face is displaceable along the guide rail, in the longitudinal direction of the guide rail, which rests on a workpiece so as to have a tool engaging in the workpiece, characterised in that the insert plate can be inserted into the receiving opening by means of a push-in-pivoting movement, hinge retaining pins arranged on the edge of the receiving opening entering hook-receiving openings of hook elements located on the edge of the insert plate and forming a pivot axis when the hinge retaining pins abut against a rear end of the retaining opening, the other side of the insert plate, when fully pivoted in, being supported on latching pins which also protrude from the two longitudinal side edges of the receiving opening and latch with latching elements on the lower edge of the insert plate.
A method of cruise control whereby a following vehicle can be caused to travel at a target speed, subject to maintaining a pre-determined distance from a leading vehicle in substantially straight travel, the method comprising: transmitting a signal from the following vehicle to the leading vehicle; receiving at the following vehicle a reflection of said signal from the leading vehicle; and determining from said reflection, by means of measuring means, a separation distance of the leading vehicle and following vehicle and maintaining the predetermined separation distance from the leading vehicle; the method being characterised by determining from said reflection, by means of deviation detection means, a deviation of the leading vehicle from a substantially straight path and an instant location of the deviation; and preventing automatic acceleration of the following vehicle until reaching said instant location in dependence on the detection of a deviation. transmitting a signal from the following vehicle to the leading vehicle; receiving at the following vehicle a reflection of said signal from the leading vehicle; and determining from said reflection, by means of measuring means, a separation distance of the leading vehicle and following vehicle and maintaining the predetermined separation distance from the leading vehicle; the method being characterised by determining from said reflection, by means of deviation detection means, a deviation of the leading vehicle from a substantially straight path and an instant location of the deviation; and preventing automatic acceleration of the following vehicle until reaching said instant location in dependence on the detection of a deviation.
A piercer plug comprising: a tip portion; and a trunk portion made of the same material as the tip portion and continuous to the tip portion, wherein the trunk portion includes a cylindrical portion having a hole used for attaching a bar, characterized in that the tip portion is harder than the cylindrical portion. a tip portion; and a trunk portion made of the same material as the tip portion and continuous to the tip portion, wherein the trunk portion includes a cylindrical portion having a hole used for attaching a bar, characterized in that the tip portion is harder than the cylindrical portion.
A process for preparing a polymer latex comprising encapsulated pigment particles, said process comprising the steps of: a) Providing a first dispersion comprising water, at least one surfactant and at least one particulate, inorganic pigment of which the particles have a mean diameter of from 200 nm to 10 μm, the mean particle diameter being a 50% particle diameter determined upon calculation of volume average particle diameter from measurements obtained using a coulter LS230 Particle Sizer. b) Providing a second dispersion comprising water, a dispersant, a hydrophobe and at least two polymerizable monomers, of which monomers at least one is an acrylic monomer; c) Independently homogenizing the first and / or second dispersion; d) Mixing said first and second homogenized dispersions and homogenizing said mixture until the particles of pigment are encapsulated by monomer droplets; and e) Initiating polymerization of the monomers, wherein the dispersant of the second dispersion is an amphiphilic polymer selected from the group consisting of: polyvinylpyrrolidone; alkylated polyvinylpyrrolidone; polyethylene glycol; poly(vinylpyrrolidone-co-vinyl acetate); poly(styrenesulfonate); poly(diallyldimethylammonium chloride); poly(ethylene-co-methacrylic acid); poly(ethylene-co-maleic acid); poly(styrene-co-maleic acid); poly(vinylimidazole); block and random copolymers of the aforementioned polymers; and, mixtures thereof. a) Providing a first dispersion comprising water, at least one surfactant and at least one particulate, inorganic pigment of which the particles have a mean diameter of from 200 nm to 10 μm, the mean particle diameter being a 50% particle diameter determined upon calculation of volume average particle diameter from measurements obtained using a coulter LS230 Particle Sizer. b) Providing a second dispersion comprising water, a dispersant, a hydrophobe and at least two polymerizable monomers, of which monomers at least one is an acrylic monomer; c) Independently homogenizing the first and / or second dispersion; d) Mixing said first and second homogenized dispersions and homogenizing said mixture until the particles of pigment are encapsulated by monomer droplets; and e) Initiating polymerization of the monomers,
A box for storing produce comprising: a base comprising a front panel, a rear panel, and a pair of opposing side panels (11,15), wherein the front, rear, and opposing side panels define a top opening, wherein the base comprises at least one cutout extending inwardly from a top edge of a select one or more of the front, rear, and opposing side panels adjacent to the top opening, wherein the at least one cutout has a substantially rectangular shape; and a lid comprising a front panel, a rear panel, and a pair of opposing side panels (31, 35), wherein the front, rear, and opposing side panels define a top opening, wherein the lid comprises at least one cutout extending inwardly from a top edge of a select one or more of the front, rear, and opposing side panels adjacent to the top opening; wherein the lid is positionable about the base such that the at least one cutout of the lid is aligned with the at least one cutout of the base; characterized in that the cutout in the base extends along about 30% to about 55% of a length of the top edge of the select one or more of the front, rear, and opposing side panels. a base comprising a front panel, a rear panel, and a pair of opposing side panels (11,15), wherein the front, rear, and opposing side panels define a top opening, wherein the base comprises at least one cutout extending inwardly from a top edge of a select one or more of the front, rear, and opposing side panels adjacent to the top opening, wherein the at least one cutout has a substantially rectangular shape; and a lid comprising a front panel, a rear panel, and a pair of opposing side panels (31, 35), wherein the front, rear, and opposing side panels define a top opening, wherein the lid comprises at least one cutout extending inwardly from a top edge of a select one or more of the front, rear, and opposing side panels adjacent to the top opening; wherein the lid is positionable about the base such that the at least one cutout of the lid is aligned with the at least one cutout of the base; characterized in that the cutout in the base extends along about 30% to about 55% of a length of the top edge of the select one or more of the front, rear, and opposing side panels.
A lithographic apparatus comprising: a substrate table configured to hold a substrate; a projection system configured to project a patterned beam onto a target portion of the substrate; and a liquid supply system configured to provide an immersion liquid to a space between the substrate and the projection system, the liquid supply system comprising a barrier member extending along at least a part of the boundary of the space and being moveable relative to the substrate table in a z axis of the apparatus or another axis perpendicular to the z axis, wherein at least one outlet (60, 66) is provided, the outlet (60, 66) being positioned radially outward of and external to the barrier member, the at least one outlet (60, 66) being provided: above the substrate table; at an edge of the substrate table; or both. a substrate table configured to hold a substrate; a projection system configured to project a patterned beam onto a target portion of the substrate; and a liquid supply system configured to provide an immersion liquid to a space between the substrate and the projection system, the liquid supply system comprising a barrier member extending along at least a part of the boundary of the space and being moveable relative to the substrate table in a z axis of the apparatus or another axis perpendicular to the z axis, wherein at least one outlet (60, 66) is provided, the outlet (60, 66) being positioned radially outward of and external to the barrier member, the at least one outlet (60, 66) being provided: above the substrate table; at an edge of the substrate table; or both.
An H1 receptor antagonist and an H2 receptor antagonist for use in treating diarrhea in a patient, wherein the patient has chemotherapy induced diarrhea, and the H1 receptor antagonist comprises cetirizine, levocetirizine, or mixtures thereof.
A method for a computer system to perform radiotherapy treatment planning based on continuous deep learning, wherein the method comprises: obtaining a deep learning engine (320, 420, 520) that is trained to perform a radiotherapy treatment planning task based on first training data (310, 410, 510) associated with a first planning rule; based on input data (330, 430, 530) associated with a particular patient, performing the radiotherapy treatment planning task using the deep learning engine (320, 420, 520) to generate output data (340, 440, 540) associated with the particular patient; characterized by: obtaining modified output data (350, 450, 550) that includes one or more modifications to the output data (340, 440, 540) generated by the deep learning engine (320, 420, 520); based on the modified output data (350, 450, 550), generating second training data (360, 460, 560) associated with a second planning rule; and generating a modified deep learning engine (380, 480, 580) by re-training the deep learning engine (320, 420, 520) using a combination of the first training data (310, 410, 510) and the second training data (360, 460, 560). obtaining a deep learning engine (320, 420, 520) that is trained to perform a radiotherapy treatment planning task based on first training data (310, 410, 510) associated with a first planning rule; based on input data (330, 430, 530) associated with a particular patient, performing the radiotherapy treatment planning task using the deep learning engine (320, 420, 520) to generate output data (340, 440, 540) associated with the particular patient; characterized by: obtaining modified output data (350, 450, 550) that includes one or more modifications to the output data (340, 440, 540) generated by the deep learning engine (320, 420, 520); based on the modified output data (350, 450, 550), generating second training data (360, 460, 560) associated with a second planning rule; and generating a modified deep learning engine (380, 480, 580) by re-training the deep learning engine (320, 420, 520) using a combination of the first training data (310, 410, 510) and the second training data (360, 460, 560). obtaining modified output data (350, 450, 550) that includes one or more modifications to the output data (340, 440, 540) generated by the deep learning engine (320, 420, 520); based on the modified output data (350, 450, 550), generating second training data (360, 460, 560) associated with a second planning rule; and generating a modified deep learning engine (380, 480, 580) by re-training the deep learning engine (320, 420, 520) using a combination of the first training data (310, 410, 510) and the second training data (360, 460, 560).
Use of bond functionalized polymer crosslinking agent with bond functions which are each localized in the area of the molecular termini of the crosslinking agent, having at least one peptide component and at least one high-molecular linear polymer component bonded to the at least one peptide component to form a linear molecule and having a molecular weight of 3 kDa or more, for crosslinking complementary bond functionalized polymers to form a two-component or multicomponent hydrogel.
A method for positioning a disc-shaped blank (16, 116, 216), which after insertion in a holder is in contact therewith, wherein the holder (10, 110) has a structural element (32, 119, 121) such as a recess, such as a depression or a projection, wherein the blank (16, 116, 216) is positioned in the holder (10, 110) by means of an adapter (18, 118), which is inserted in both the holder (10, 110) and the structural element (32, 119, 121), and the blank (16, 116, 216), wherein the adapter positively engages with the holder (10, 110) and the structural element (32, 119, 121), and with the blank (16, 116, 216); wherein the blank (16, 116, 216) after positioning in the holder (10, 110) is processed, removed from the holder and then repositioned in the holder by means of the adapter (18, 118); wherein the blank (16, 116, 216) is provided with a mechanical referencing (34, 134), such as a recess, such as a groove, which interacts with a first section (46, 146) of the adapter (18, 118) for positioning of the blank, the first section (46, 146) penetrates into the mechanical referencing; and wherein for unambiguous positioning of the blank (16, 116, 216) the adapter (18, 118) with a second section (36, 136) interacts with the structural element (34, 119, 121) and with the first section (46, 146) interacts with the mechanical referencing (34, 134) of the blank, wherein between the first section and the second section a section of the adapter (18, 118) bridges over a section of the holder (10, 110). and the blank (16, 116, 216), wherein the adapter positively engages with the holder (10, 110) and the structural element (32, 119, 121), and with the blank (16, 116, 216); wherein the blank (16, 116, 216) after positioning in the holder (10, 110) is processed, removed from the holder and then repositioned in the holder by means of the adapter (18, 118); wherein the blank (16, 116, 216) is provided with a mechanical referencing (34, 134), such as a recess, such as a groove, which interacts with a first section (46, 146) of the adapter (18, 118) for positioning of the blank, the first section (46, 146) penetrates into the mechanical referencing; and wherein for unambiguous positioning of the blank (16, 116, 216) the adapter (18, 118) with a second section (36, 136) interacts with the structural element (34, 119, 121) and with the first section (46, 146) interacts with the mechanical referencing (34, 134) of the blank, wherein between the first section and the second section a section of the adapter (18, 118) bridges over a section of the holder (10, 110).
A microstrip antenna (14, 37) comprising: - at least one dielectric material (15, 38) forming a dielectric layer structure having a first main side (16, 39), - at least one antenna structure (18, 41) formed on the first main side (16, 39); and - a ground plane (19, 43), where the dielectric layer structure (15, 38) is positioned between said antenna structure (18, 41) and the ground plane (19, 43), where each of said at least one antenna structure (18, 41) comprises a microstrip conductor (20, 44) that in turn comprises a slot structure (21, 45), where, for each of said at least one antenna structure (18, 41), the microstrip conductor (20, 44) and the slot structure (21, 45) mainly extend in the direction of a longitudinal extension (22, 42), wherein the antenna structure (18, 41) has a constant total width (w t) along the longitudinal extension (22, 42), characterised in that the slot structure divides the microstrip conductor in a first conductor part and a second conductor part that extend parallel to each other, where the slot structure has a varying width that varies step-wise between different values and for different lengths along the longitudinal extension. - at least one dielectric material (15, 38) forming a dielectric layer structure having a first main side (16, 39), - at least one antenna structure (18, 41) formed on the first main side (16, 39); and - a ground plane (19, 43),
A material for a non-aqueous electrolyte secondary battery anode; a specific surface area of the material determined by a BET method being not greater than 30 m 2 /g; an atomic ratio,H/C, of hydrogen atoms to carbon atoms of the material determined by elemental analysis being not greater than 0.1; an average particle size of the material being not greater than 50 μm; and a diffraction intensity ratio (R-value) determined by Equation being not greater than 1.25: [Formula 1] R = I max − I 35 I min − I 35 wherein I max is a maximum value of a 002 diffraction intensity of carbon measured at an angle of diffraction (2θ) within a range of from 20 to 25° as determined by powder X-ray diffraction measured using CuKa rays; I min is a minimum value of a diffraction intensity measured at an angle of diffraction (2θ) within a range of from 15 to 20° as determined by powder X-ray diffraction; and I 35 is a diffraction intensity at an angle of diffraction (2θ) of 35° as determined by powder X-ray diffraction.
A semiconductor device, comprising: an isolation structure; a first active area formed on the isolation structure; a protection area formed on the isolation structure and laterally surrounding the first active area; a second active area formed on the isolation structure and laterally surrounding the protection area; a first trench isolation structure electrically separating the first active area and the protection area; a second trench isolation structure electrically separating the protection area and the second active area; and a protection structure in the protection area, wherein a first pin of the protection structure is electrically connected to the first active area and a second pin of the protection structure is electrically connected to the second active area, characterized in that the protection structure comprises a plurality of protection elements consecutively arranged substantially along a sidewall of the first trench isolation structure and serially connected to one another substantially along the sidewall of the first trench isolation structure,and each of or groups of the plurality of protection elements are laterally surrounded by a closed-loop trench device isolation structure not surrounding the first active area. an isolation structure; a first active area formed on the isolation structure; a protection area formed on the isolation structure and laterally surrounding the first active area; a second active area formed on the isolation structure and laterally surrounding the protection area; a first trench isolation structure electrically separating the first active area and the protection area; a second trench isolation structure electrically separating the protection area and the second active area; and a protection structure in the protection area, wherein a first pin of the protection structure is electrically connected to the first active area and a second pin of the protection structure is electrically connected to the second active area, characterized in that the protection structure comprises a plurality of protection elements consecutively arranged substantially along a sidewall of the first trench isolation structure and serially connected to one another substantially along the sidewall of the first trench isolation structure,and each of or groups of the plurality of protection elements are laterally surrounded by a closed-loop trench device isolation structure not surrounding the first active area.
A closure part for a connecting rod fitting of a window or of a door comprising a base body; and a holding part supported in a vertically adjustable manner at the base body, wherein the holding part has at least one reception opening for receiving a latching element of a leaf of the window or of the door; wherein the reception opening extends in a U-shaped manner and forms a holding edge for engaging behind the latching element; and wherein the latching element is arranged at a connecting rod displaceably supported at the leaf and is linearly displaceable together with said connecting rod between a release position and a blocked position, characterized in that at least one magnetic region (33A, 33B, 33C) is provided at the holding part and comprises a permanent magnet and/or is configured as ferromagnetic for a vertical adjustment of the holding part with respect to the base body.