mhurhangee/ep-ind-claims huggingface dataset:
An apparatus for producing an immune response by thermal treatment of a tumor, said apparatus comprises: a first lead (32, 34, 205, 207) configured to be arranged within and/or near boundaries of said tumor to be heat treated, said first lead comprises a heat source, wherein said heat source is a laser light source (13, 15) connectable to a light conducting fibre for conducting light from said light source to a point at said first lead; a thermal sensor (55, 57, 59, 61) on said first lead configured for measuring a first temperature; characterized by said first lead comprises a laser light transparent energy emission window, or a bare fibre tip, and is further provided with a scale and a sleeve (281, 283) with a reference point for determining a depth of said energy emission window, or said bare fibre tip, when said first lead is being positioned; a control unit configured to adjust a power output of said heat source based on said measured first temperature, so that said first temperature is a constant temperature in a range of 42.5°C to 48°C during treatment. a first lead (32, 34, 205, 207) configured to be arranged within and/or near boundaries of said tumor to be heat treated, said first lead comprises a heat source, wherein said heat source is a laser light source (13, 15) connectable to a light conducting fibre for conducting light from said light source to a point at said first lead; a thermal sensor (55, 57, 59, 61) on said first lead configured for measuring a first temperature; characterized by said first lead comprises a laser light transparent energy emission window, or a bare fibre tip, and is further provided with a scale and a sleeve (281, 283) with a reference point for determining a depth of said energy emission window, or said bare fibre tip, when said first lead is being positioned; a control unit configured to adjust a power output of said heat source based on said measured first temperature, so that said first temperature is a constant temperature in a range of 42.5°C to 48°C during treatment.
Knife having a handle which is made of plastics material and fastened to the blade, having a first recess which opens towards the end of the handle and is closed by an end cap or end disc made of plastics material or metal, wherein the end cap/end disc rests in or on the recess, and at least two tongues, which are parallel to the handle longitudinal axis, are integrally moulded on the rear side of the end cap/end disc, said at least two tongues protruding into a longitudinal recess which proceeds from the first recess and protrudes inwards in the direction of the blade, characterized in that the internal wall of the longitudinal recess has longitudinal ribs which are made of plastics material and are parallel to the handle longitudinal axis and project on opposite wall sides, and the free ends of the tongues have on the external side at least one tooth, or a toothed strip, which is/are held in the longitudinal rib so as to engage in the latter in a claw-like manner, wherein the tongues, the teeth and/or the toothed strips are composed of a material harder than the plastics material of the longitudinal ribs.
A speech/audio signal processing method, comprising: when a speech/audio signal switches from a wide frequency signal to a narrow frequency signal, obtaining an initial high frequency signal corresponding to a current frame of speech/audio signal; obtaining a time-domain global gain parameter of the initial high frequency signal; performing weighting processing on an energy ratio and the time-domain global gain parameter, and using an obtained weighted value as a predicted global gain parameter, wherein the energy ratio is a ratio between energy of a high frequency time-domain signal of a historical frame and energy of the initial high frequency signal of the current frame; correcting the initial high frequency signal by using the predicted global gain parameter, to obtain a corrected high frequency time-domain signal; and synthesizing a narrow frequency time-domain signal of the current frame and the corrected high frequency time-domain signal and outputting the synthesized signal. when a speech/audio signal switches from a wide frequency signal to a narrow frequency signal, obtaining an initial high frequency signal corresponding to a current frame of speech/audio signal; obtaining a time-domain global gain parameter of the initial high frequency signal; performing weighting processing on an energy ratio and the time-domain global gain parameter, and using an obtained weighted value as a predicted global gain parameter, wherein the energy ratio is a ratio between energy of a high frequency time-domain signal of a historical frame and energy of the initial high frequency signal of the current frame; correcting the initial high frequency signal by using the predicted global gain parameter, to obtain a corrected high frequency time-domain signal; and synthesizing a narrow frequency time-domain signal of the current frame and the corrected high frequency time-domain signal and outputting the synthesized signal.
An air conditioner indoor unit, two opposite sides of the air conditioner indoor unit being an air outlet side and a leeward side respectively, and the air conditioner indoor unit comprising: a panel assembly and an air outlet frame inserted to the panel assembly, a length direction of the air outlet frame being defined as a first dimension, a width direction of the air outlet frame being defined as a second dimension, a plane perpendicular to the first dimension and the second dimension being defined as a third dimension, wherein the panel assembly defines a mounting through cavity provided close to the air outlet side, the air outlet frame is mounted at the mounting through cavity, the panel assembly is provided with an assembly strip at an edge of the mounting through cavity, the assembly strip defines a first through hole and a second through hole therein, the air outlet frame is provided with a snap hook and an insertion plate at an edge thereof, the snap hook passes through the first through hole and is hooked to an outside of the assembly strip to limit movement of the air outlet frame in the third dimension, the insertion plate is inserted into the second through hole and slides in the second through hole, and the insertion plate has a front end clamped to a front end of the second through hole in an insertion direction, the insertion plate limits movement of the air outlet frame in the first dimension and the second dimension.
The compound FK506 for use in the treatment of pulmonary arterial hypertension in a human subject having pulmonary arterial hypertension associated with defective BMPR2 signaling, wherein said FK506 is administered at a dosage of 0.002 mg/kg of the subject's weight per day to 0.05 mg/kg of the subject's weight per day.
A stapling assembly for use with a surgical stapler, comprising: a cartridge having a plurality of staples disposed therein, the plurality of staples being configured to be deployed into tissue; and a non-fibrous adjunct formed of at least one fused bioabsorbable polymer and configured to be releasably retained on the cartridge such that the adjunct can be attached to tissue by the plurality of staples in the cartridge, the adjunct comprising, a lattice structure being formed a plurality of repeating unit cells, each unit cell having a geometry that forms at least one tissue-facing surface having planar and non-planar surfaces, and characterised in that the stapling assembly further comprises an absorbable film that is positioned on at least a portion of the at least one tissue-facing surface of the lattice structure to thereby substantially prevent tissue from causing the first lattice structure from detaching from the cartridge while the tissue slides across the adjunct. a cartridge having a plurality of staples disposed therein, the plurality of staples being configured to be deployed into tissue; and a non-fibrous adjunct formed of at least one fused bioabsorbable polymer and configured to be releasably retained on the cartridge such that the adjunct can be attached to tissue by the plurality of staples in the cartridge, the adjunct comprising, a lattice structure being formed a plurality of repeating unit cells, each unit cell having a geometry that forms at least one tissue-facing surface having planar and non-planar surfaces, and characterised in that the stapling assembly further comprises an absorbable film that is positioned on at least a portion of the at least one tissue-facing surface of the lattice structure to thereby substantially prevent tissue from causing the first lattice structure from detaching from the cartridge while the tissue slides across the adjunct. a lattice structure being formed a plurality of repeating unit cells, each unit cell having a geometry that forms at least one tissue-facing surface having planar and non-planar surfaces, and characterised in that the stapling assembly further comprises an absorbable film that is positioned on at least a portion of the at least one tissue-facing surface of the lattice structure to thereby substantially prevent tissue from causing the first lattice structure from detaching from the cartridge while the tissue slides across the adjunct.
A subchannel encoding device, comprising: an information bit string separating unit for separating one information bit string into N groups and M × N subchannels, with M and N each being an integer of two or more a probability distribution shaping-encoding unit provided with N probability distribution shaping-encoding processing units -(72-N) for shaping a probability distribution of transmission modulation symbols corresponding to the information bit string belonging to each group separated by the information bit string separating unit on a basis of signal-to-noise ratios of the M × N subchannels, and converting the information bit string belonging to each group into a shaped bit string corresponding to the probability distribution of the shaped transmission modulation symbols; a subchannel signal generating unit for generating each subchannel signal in the M × N subchannels from the N shaped bit strings; and a signal multiplexing unit for multiplexing the M × N subchannel signals generated by the subchannel signal generating unit to generate a subchannel multiplexed signal. an information bit string separating unit for separating one information bit string into N groups and M × N subchannels, with M and N each being an integer of two or more a probability distribution shaping-encoding unit provided with N probability distribution shaping-encoding processing units -(72-N) for shaping a probability distribution of transmission modulation symbols corresponding to the information bit string belonging to each group separated by the information bit string separating unit on a basis of signal-to-noise ratios of the M × N subchannels, and converting the information bit string belonging to each group into a shaped bit string corresponding to the probability distribution of the shaped transmission modulation symbols; a subchannel signal generating unit for generating each subchannel signal in the M × N subchannels from the N shaped bit strings; and a signal multiplexing unit for multiplexing the M × N subchannel signals generated by the subchannel signal generating unit to generate a subchannel multiplexed signal.
An adapter supporting a first charging mode and a second charging mode, comprising: a power converting circuit, configured to convert inputted alternating current, AC, to generate output voltage and output current of the adapter, the power converting circuit comprising a secondary filter circuit; a control circuit, coupled to the secondary filter circuit and configured to control the secondary filter circuit to operate when the adapter operates in the first charging mode, so that the adapter outputs constant direct current, and configured to control the secondary filter circuit not to operate when the adapter operates in the second charging mode, so that the adapter outputs an alternating current or a pulsating direct current; wherein a speed by which the adapter operable in the second charging mode charges a chargeable device is faster than a speed by which the adapter operable in the first charging mode charges the chargeable device. a power converting circuit, configured to convert inputted alternating current, AC, to generate output voltage and output current of the adapter, the power converting circuit comprising a secondary filter circuit; a control circuit, coupled to the secondary filter circuit and configured to control the secondary filter circuit to operate when the adapter operates in the first charging mode, so that the adapter outputs constant direct current, and configured to control the secondary filter circuit not to operate when the adapter operates in the second charging mode, so that the adapter outputs an alternating current or a pulsating direct current; wherein a speed by which the adapter operable in the second charging mode charges a chargeable device is faster than a speed by which the adapter operable in the first charging mode charges the chargeable device.
An extrusion foam process, the process comprising preparing at a mixing pressure a foamable polymer mixture comprising a thermoplastic polymer and a blowing agent, cooling the foamable polymer mixture and extruding it in an extrusion direction through a foaming die at a die pressure and out of the foaming die through a die opening at a flow rate into an atmosphere of low enough pressure to allow the foamable polymer mixture to expand into a polymer foam while traveling in the extrusion direction at an extrusion rate, the extrusion foam process being further characterized by: a. the die pressure being at least 90 bars lower than the mixing pressure; b. all cross sectional dimensions of the die opening being at least 2.5 millimeters and the cross sectional area of the die opening being at least 700 square millimeters; c. the flow rate of the foamable polymer mixture through the die opening being greater than 500 kilograms per hour; d. the foamable polymer mixture expands between restraining elements positioned immediately after the foaming die; e. a device positioned after the restraining elements that restrains the extrusion rate of the polymer foam relative to its unrestrained extrusion rate; and wherein the polymer foam characterized by having a continuous thermoplastic polymer matrix defining cells therein, a void volume of 96 volume percent or less based on total polymer foam volume, a cell size dimensional ratio in the polymer foam thickness dimension to its width and length dimension that is greater than one, and a thickness of 50 millimeters or more, a compressive modulus and tensile modulus in the thickness dimension that is greater than 35 mega pascals and an average shear modulus between its thickness/width and thickness/length dimensions that is greater than sixteen mega pascals. a. the die pressure being at least 90 bars lower than the mixing pressure; b. all cross sectional dimensions of the die opening being at least 2.5 millimeters and the cross sectional area of the die opening being at least 700 square millimeters; c. the flow rate of the foamable polymer mixture through the die opening being greater than 500 kilograms per hour; d. the foamable polymer mixture expands between restraining elements positioned immediately after the foaming die; e. a device positioned after the restraining elements that restrains the extrusion rate of the polymer foam relative to its unrestrained extrusion rate;
A control device for a machining apparatus including a multi-joint arm provided with a machining tool for machining a machining object which is supported in a cantilever fashion, without being supported in the vicinity of a machining region that is to be machined by the machining apparatus, and which has a plurality of machining surfaces each corresponding to a different face of the machining object, the control device comprising: a storage means that is arranged to store machining data indicating the machining region of the machining object, wherein the machining data is divided according to the different machining surfaces so that the divided machining data respectively correspond to each of the machining surfaces; a distance measurement means placed on the arm and arranged to measure the distance between the machining object and the machining apparatus at at least two locations for each of the plurality of machining surfaces; and a correction means that is arranged to correct the machining data for each of the plurality of machining surfaces based on a measurement result by the distance measurement means, the control device characterised in that the correction means is arranged to calculate a rotational center of deflection-caused deviation between an actual position of the machining region of the machining object and a position thereof indicated by the machining data based on a measurement result by the distance measurement means, and to correct the machining data based on the calculated rotational center. a storage means that is arranged to store machining data indicating the machining region of the machining object, wherein the machining data is divided according to the different machining surfaces so that the divided machining data respectively correspond to each of the machining surfaces; a distance measurement means placed on the arm and arranged to measure the distance between the machining object and the machining apparatus at at least two locations for each of the plurality of machining surfaces; and a correction means that is arranged to correct the machining data for each of the plurality of machining surfaces based on a measurement result by the distance measurement means, the control device characterised in that the correction means is arranged to calculate a rotational center of deflection-caused deviation between an actual position of the machining region of the machining object and a position thereof indicated by the machining data based on a measurement result by the distance measurement means, and to correct the machining data based on the calculated rotational center.
An offshore cryogenic offloading system that lies in a sea having a sea surface and a sea floor, wherein cryogenic fluid is transferred between two floating units in a bow to stem configuration, said system comprising: - a floating structure that lies at the sea surface and comprises processing units - a floating tanker that lies at the sea surface and transports the cryogenic fluids from one location to another said tanker having a bow loading station; - at least one cryogenic transfer line (3b, 3c) that extends from the stem of said floating structure to the bow of said floating tanker to carry cryogenic fluids from one to the other; - at least one transfer line acting as vapor return line that extends from the stem of said floating structure to the bow of said floating tanker to carry the boil-off vapor from the floating tanker to the floating structure in normal operations; wherein the bow of the floating tanker is provided with an additional level comprising a fluid connection deck placed on the top of a bow upper deck, characterised in that the bow of the floating tanker is provided with a third level comprising a tandem mooring offloading deck placed on top of the fluid connection deck to enable the two floating units (1, 2) to be releasably moored one to the other, wherein all mooring and handling elements are located on the bow loading station at the tandem mooring offloading deck at a different level than fluid connecting elements which are at the fluid connection deck. - a floating structure that lies at the sea surface and comprises processing units - a floating tanker that lies at the sea surface and transports the cryogenic fluids from one location to another said tanker having a bow loading station; - at least one cryogenic transfer line (3b, 3c) that extends from the stem of said floating structure to the bow of said floating tanker to carry cryogenic fluids from one to the other; - at least one transfer line acting as vapor return line that extends from the stem of said floating structure to the bow of said floating tanker to carry the boil-off vapor from the floating tanker to the floating structure in normal operations; wherein the bow of the floating tanker is provided with an additional level comprising a fluid connection deck placed on the top of a bow upper deck,
Computer-implemented method for training a normalizing flow, wherein the normalizing flow is configured to predict a first density value based on a first input image (x), wherein the first density value characterizes a likelihood of the first input image to occur, wherein the first density value is predicted based on an intermediate output of a first convolutional layer of the normalizing flow, wherein the intermediate output is determined based on a plurality of weights of the first convolutional layer, wherein the method for training comprises the steps of: • Determining a second input image (x i); • Determining an output ( ŷ i), wherein the output (ŷ i) is determined by providing the second input image (x i) to the normalizing flow and providing an output of the normalizing flow as output ( ŷ i); • Determining a second density value based on the output tensor and on the plurality of weights; • Determining a natural gradient of the plurality of weights with respect to the second density value, wherein the natural gradient is determined according to the formula: ∇ w l = δ l ⋆ w l ⋆ T h l T + w l ⋅ H l ⋅ W l, wherein ∇ w l is the natural gradient, δ l is an error signal for the first convolutional layer, w l is the plurality of weights, H l is a height of a layer input of the first convolutional layer, W l is a width of the layer input, ★ denotes a convolution operation and ★ T denotes a transposed convolution operation; · Adapting the plurality of weights according to the natural gradient. • Determining a second input image (x i); • Determining an output ( ŷ i), wherein the output (ŷ i) is determined by providing the second input image (x i) to the normalizing flow and providing an output of the normalizing flow as output ( ŷ i); • Determining a second density value based on the output tensor and on the plurality of weights; • Determining a natural gradient of the plurality of weights with respect to the second density value, wherein the natural gradient is determined according to the formula: ∇ w l = δ l ⋆ w l ⋆ T h l T + w l ⋅ H l ⋅ W l, wherein ∇ w l is the natural gradient, δ l is an error signal for the first convolutional layer, w l is the plurality of weights, H l is a height of a layer input of the first convolutional layer, W l is a width of the layer input, ★ denotes a convolution operation and ★ T denotes a transposed convolution operation; · Adapting the plurality of weights according to the natural gradient.
Multi-layer liquid purification element having a liquid-permeable top layer and having a liquid-impermeable base layer, wherein the base layer has a suction port for the drawing-in of liquid through the liquid purification element, and at least the top layer and the base layer are connected to one another by means of a liquid-impermeable connection, wherein, between the top layer and the base layer, there is arranged at least one separate insert (6, 7) and wherein the liquid purification element constitutes an areal element which has a thickness significantly smaller than the maximum areal extent along the top layer or along the base layer.