A prosthesis for repairing a hernia defect, the prosthesis comprising: a patch body having a periphery, a first axis and a second axis perpendicular to the first axis, the first axis and the second axis intersecting at approximately a center of the patch body, a first portion of the patch body on one side of the first axis and a second portion of the patch body on the other side of the first axis; a self-expanding hoisting frame releasably attachable to the patch body to assist in spreading the patch body from a reduced configuration to an expanded configuration, the self-expanding hoisting frame including an outer frame component and a force translation component, the outer frame component defining an open interior and the force translation component extending through the open interior; and a tether attached to the force translation component, a free end of the tether extendable away from the force translation component and through the patch body when the hoisting frame is releasably attached to the patch body, a pulling force on the free end of the tether in an outward direction away from the patch body being directed by the force translation component in the direction of the outer frame component when the patch body is in the expanded configuration; and a self-expanding support member coupled to the outer frame component to assist in expanding the hoisting frame from a reduced configuration to an expanded configuration, the support member being coupled to the outer frame component to constrain movement of the support member at one or more first regions of the outer frame component while allowing movement of the support member at one or more second regions of the outer frame component in response to manipulating the hoisting frame from the expanded configuration to the reduced configuration, the movement of the support member being greater at the one or more second regions than at the one or more first regions, wherein the patch body and the hoisting frame when releasably attached to the patch body are manipulable into the reduced configuration for insertion through an opening into a patient. a patch body having a periphery, a first axis and a second axis perpendicular to the first axis, the first axis and the second axis intersecting at approximately a center of the patch body, a first portion of the patch body on one side of the first axis and a second portion of the patch body on the other side of the first axis; a self-expanding hoisting frame releasably attachable to the patch body to assist in spreading the patch body from a reduced configuration to an expanded configuration, the self-expanding hoisting frame including an outer frame component and a force translation component, the outer frame component defining an open interior and the force translation component extending through the open interior; and a tether attached to the force translation component, a free end of the tether extendable away from the force translation component and through the patch body when the hoisting frame is releasably attached to the patch body, a pulling force on the free end of the tether in an outward direction away from the patch body being directed by the force translation component in the direction of the outer frame component when the patch body is in the expanded configuration; and a self-expanding support member coupled to the outer frame component to assist in expanding the hoisting frame from a reduced configuration to an expanded configuration, the support member being coupled to the outer frame component to constrain movement of the support member at one or more first regions of the outer frame component while allowing movement of the support member at one or more second regions of the outer frame component in response to manipulating the hoisting frame from the expanded configuration to the reduced configuration, the movement of the support member being greater at the one or more second regions than at the one or more first regions, wherein the patch body and the hoisting frame when releasably attached to the patch body are manipulable into the reduced configuration for insertion through an opening into a patient.