A hybrid type filtration structure comprising: a first active layer having a first nano pore passing vertically through the first active layer, the first nano pore having an inner wall and a maximum pore diameter less than 50 nm, wherein the first active layer comprises a copolymer selected from a styrene-acrylic acid block copolymer, a styrene-lactic acid block copolymer, and a styrene-acrylic oxide block copolymer; a porous supporting layer having a plurality of pores and being disposed under the first active layer; and a permeable layer disposed under the porous supporting layer, wherein the porous supporting layer comprises a plurality of lipid bilayers inside of the pores, wherein the lipid bilayers comprise membrane proteins for selectively passing molecules of water therethrough, wherein the membrane protein comprises aquaporin or aquaglyceroporin, and the porous supporting layer comprises a polymer selected from polysulfone, polyethersulfone, polyphenylsulfone, polyetherethersulfone, polyetherketone, polyetheretherketone, polyphenyleneether, polydiphenylphenyleneether, polyvinylene cellulose acetate, cellulose diacetate, cellulose triacetate, polyphenylenesulphide, nitrocellulose, acetylation methyl cellulose, polyacrylonitrile, polyvinyl alcohol, polycarbonate, organic siloxane carbonate, polyester carbonate, organic polysiloxane, polyethylene oxide, polyamide, polyimide, polyamide-imide and polybenzimidazole; wherein the first nano pore and the pores are connected for allowing liquid flow through the structure; wherein the inner wall of the first nano pore comprises an active group, the active group being combined with a functional group; characterised in that the functional group comprises a peptide functional group comprising a single arginine-phenylalanine unit or a plurality of arginine-phenylalanine units. a first active layer having a first nano pore passing vertically through the first active layer, the first nano pore having an inner wall and a maximum pore diameter less than 50 nm, wherein the first active layer comprises a copolymer selected from a styrene-acrylic acid block copolymer, a styrene-lactic acid block copolymer, and a styrene-acrylic oxide block copolymer; a porous supporting layer having a plurality of pores and being disposed under the first active layer; and a permeable layer disposed under the porous supporting layer, wherein the porous supporting layer comprises a plurality of lipid bilayers inside of the pores, wherein the lipid bilayers comprise membrane proteins for selectively passing molecules of water therethrough, wherein the membrane protein comprises aquaporin or aquaglyceroporin, and the porous supporting layer comprises a polymer selected from polysulfone, polyethersulfone, polyphenylsulfone, polyetherethersulfone, polyetherketone, polyetheretherketone, polyphenyleneether, polydiphenylphenyleneether, polyvinylene cellulose acetate, cellulose diacetate, cellulose triacetate, polyphenylenesulphide, nitrocellulose, acetylation methyl cellulose, polyacrylonitrile, polyvinyl alcohol, polycarbonate, organic siloxane carbonate, polyester carbonate, organic polysiloxane, polyethylene oxide, polyamide, polyimide, polyamide-imide and polybenzimidazole; wherein the first nano pore and the pores are connected for allowing liquid flow through the structure; wherein the inner wall of the first nano pore comprises an active group, the active group being combined with a functional group; characterised in that the functional group comprises a peptide functional group comprising a single arginine-phenylalanine unit or a plurality of arginine-phenylalanine units.