A nuclide separating device, comprising: a column arrangement part in which a plurality of columns (C 1 - C N) are arranged; a first fluid channel through which a reagent or sample to be introduced into each of the columns arranged in the column arrangement part is transferred; a second fluid channel through which a purified sample or waste discharged from the column is delivered to a collection part; a fluid channel forming part for connecting or disconnecting the first fluid channel and the second fluid channel to or from a random column arranged in the column arrangement part; a main pump for supplying pressure to introduce the reagent or the sample into the first fluid channel and to discharge the purified sample or waste from the column; and a transfer part for transferring the fluid channel forming part so that the fluid channel forming part can connect or disconnect the first fluid channel and the second fluid channel to or from another random column arranged in the column arrangement part characterized in that the nuclide separating device is configured such that: the fluid channel forming part connects one column of the plurality of columns to the first fluid channel and the second fluid channel, the transfer part transfers the fluid channel forming part after extraction of the one column is completed, and the fluid channel forming part connects another one of the plurality of columns to the first fluid channel and the second fluid channel. a column arrangement part in which a plurality of columns (C 1 - C N) are arranged; a first fluid channel through which a reagent or sample to be introduced into each of the columns arranged in the column arrangement part is transferred; a second fluid channel through which a purified sample or waste discharged from the column is delivered to a collection part; a fluid channel forming part for connecting or disconnecting the first fluid channel and the second fluid channel to or from a random column arranged in the column arrangement part; a main pump for supplying pressure to introduce the reagent or the sample into the first fluid channel and to discharge the purified sample or waste from the column; and a transfer part for transferring the fluid channel forming part so that the fluid channel forming part can connect or disconnect the first fluid channel and the second fluid channel to or from another random column arranged in the column arrangement part characterized in that the nuclide separating device is configured such that: the fluid channel forming part connects one column of the plurality of columns to the first fluid channel and the second fluid channel, the transfer part transfers the fluid channel forming part after extraction of the one column is completed, and the fluid channel forming part connects another one of the plurality of columns to the first fluid channel and the second fluid channel. the fluid channel forming part connects one column of the plurality of columns to the first fluid channel and the second fluid channel, the transfer part transfers the fluid channel forming part after extraction of the one column is completed, and the fluid channel forming part connects another one of the plurality of columns to the first fluid channel and the second fluid channel.