A wave-driven power generation system, comprising: an upright support frame fixedly fastened to a floor; at least one water reservoir respectively holding a predetermined amount of water; a rocker bar pivotally mounted at a top end of said upright support frame in a balanced manner and drivable by an external force to turn alternatively up and down on said upright support frame, said rocker bar having a coupling means; a plurality of wave-making barrels symmetrically coupled to two opposite ends of said rocker bar and movable with said rocker bar to cause the water in each said water reservoir to create water waves, each said wave-making barrel having a top handle pivotally coupled to one end of said rocker bar; a motor reducer for turning said rocker bar alternatively up and down on said upright support frame, said motor reducer comprising an output shaft and an eccentric wheel mounted at a distal end of said output shaft and coupled to said coupling means of said rocker bar; at least one float board floating up and down with created water waves in each said water reservoir, each said float board having a first connection rod and a second connection rod fixedly connected thereto in a parallel manner; at least one power generating unit rotatable to generate electricity; at least one transmission gearbox respectively coupled between the first connection rod and second connection rod of each said float board and said at least one power generating unit for transferring a rotary driving force from said at least one float board to said at least one power generating unit; and at least one inertial wheel set respectively coupled between said at least one transmission gearbox and said at least one power generating unit. an upright support frame fixedly fastened to a floor; at least one water reservoir respectively holding a predetermined amount of water; a rocker bar pivotally mounted at a top end of said upright support frame in a balanced manner and drivable by an external force to turn alternatively up and down on said upright support frame, said rocker bar having a coupling means; a plurality of wave-making barrels symmetrically coupled to two opposite ends of said rocker bar and movable with said rocker bar to cause the water in each said water reservoir to create water waves, each said wave-making barrel having a top handle pivotally coupled to one end of said rocker bar; a motor reducer for turning said rocker bar alternatively up and down on said upright support frame, said motor reducer comprising an output shaft and an eccentric wheel mounted at a distal end of said output shaft and coupled to said coupling means of said rocker bar; at least one float board floating up and down with created water waves in each said water reservoir, each said float board having a first connection rod and a second connection rod fixedly connected thereto in a parallel manner; at least one power generating unit rotatable to generate electricity; at least one transmission gearbox respectively coupled between the first connection rod and second connection rod of each said float board and said at least one power generating unit for transferring a rotary driving force from said at least one float board to said at least one power generating unit; and at least one inertial wheel set respectively coupled between said at least one transmission gearbox and said at least one power generating unit.