A polyurethane composition comprising: a) from 80 to 99.9% by weight, based on the total weight of the polyurethane composition, of at least one polyurethane component; b) from 0.05 to 1.5% by weight (500 to 15,000 ppm), based on the total weight of the polyurethane composition, of at least one complexing agent; c) from 0.005 to 5% by weight (50 to 50,000 ppm), based on the total weight of the polyurethane composition, of at least one organic antimicrobially active component comprising at least one nitrogen atom; d) optionally up to 15% by weight, based on the total weight of the polyurethane composition, of one or more polymers different from the at least one polyurethane component and e) optionally up to 5% by weight, based on the total weight of the polyurethane composition, of one or more additives; wherein the at least one complexing agent is selected from the group consisting of organic compounds having at least two functional moieties, of which at least one functional moiety is a carboxylic acid moiety or a salt thereof; and wherein the at least one organic antimicrobially active component comprising at least one nitrogen atom is selected from the group consisting of quaternary ammonium salts having at least one C 8 -C 30 hydrocarbon moiety attached to the nitrogen atom, primary, secondary or tertiary amines having at least one C 8 -C 30 hydrocarbon moiety attached to the nitrogen atom, N-oxides of tertiary amines having at least one C 8 -C 30 hydrocarbon moiety attached to the nitrogen atom, tertiary amines having a C 8 -C 30 hydrocarbon moiety and two aminoalkyl moieties attached to the tertiary nitrogen atom, and polymers having repeating units comprising quaternary ammonium moieties or amine moieties. a) from 80 to 99.9% by weight, based on the total weight of the polyurethane composition, of at least one polyurethane component; b) from 0.05 to 1.5% by weight (500 to 15,000 ppm), based on the total weight of the polyurethane composition, of at least one complexing agent; c) from 0.005 to 5% by weight (50 to 50,000 ppm), based on the total weight of the polyurethane composition, of at least one organic antimicrobially active component comprising at least one nitrogen atom; d) optionally up to 15% by weight, based on the total weight of the polyurethane composition, of one or more polymers different from the at least one polyurethane component and e) optionally up to 5% by weight, based on the total weight of the polyurethane composition, of one or more additives; wherein the at least one complexing agent is selected from the group consisting of organic compounds having at least two functional moieties, of which at least one functional moiety is a carboxylic acid moiety or a salt thereof; and wherein the at least one organic antimicrobially active component comprising at least one nitrogen atom is selected from the group consisting of quaternary ammonium salts having at least one C 8 -C 30 hydrocarbon moiety attached to the nitrogen atom, primary, secondary or tertiary amines having at least one C 8 -C 30 hydrocarbon moiety attached to the nitrogen atom, N-oxides of tertiary amines having at least one C 8 -C 30 hydrocarbon moiety attached to the nitrogen atom, tertiary amines having a C 8 -C 30 hydrocarbon moiety and two aminoalkyl moieties attached to the tertiary nitrogen atom, and polymers having repeating units comprising quaternary ammonium moieties or amine moieties.