A compound of Formula: or a pharmaceutically acceptable salt thereof, wherein: R 1 is H or halo; G 1 is -N- or -C(R b)-, wherein R b is H or halo, or R b is taken together with R 2 and the atoms to which they are attached to form a 5- or 6-membered cycloalkyl or heterocycloalkyl ring; R 2 is H or -CH 3, or R 2 is taken together with R b and the atoms to which they are attached to form a 5- or 6-membered cycloalkyl or heterocycloalkyl ring; L 1, Y 1, and Y 2 are defined by (i) or (ii): (i) L 1 is absent; Y 1 is R x; and Y 2 is R z; or (ii) L 1 is wherein L 2 is absent, -O-, -NH-, or -OCH 2 - ∗, and wherein ∗ indicates the attachment to Y 2; Y 1 is wherein R 1aa is H, alkyl, cycloalkyl, cycloalkenyl, heterocycloalkyl, heterocycloalkenyl, aryl, or heteroaryl; and Y 2 is -CH 3, phenyl, or R z; R x is R 1a, R 1b, R 1c1, R 1c2, R 1f, R 1g, R 1h1, and R 1h2 are each independently H, alkyl, alkenyl, alkynyl, haloalkyl, -C O-alkyl, cycloalkyl, cycloalkenyl, cycloalkynyl, heterocycloalkyl, heterocycloalkenyl, aryl, or heteroaryl; R 1d1, R 1d2, and R 1d3 are each independently alkyl, alkenyl, alkynyl, haloalkyl, -C O-alkyl, cycloalkyl, cycloalkenyl, cycloalkynyl, heterocycloalkyl, heterocycloalkenyl, aryl, or heteroaryl; R 1e1 and R 1e2 are each independently H, alkyl, alkenyl, alkynyl, haloalkyl, -C O-alkyl, or a cycloalkyl, cycloalkenyl, cycloalkynyl, heterocycloalkyl, heterocycloalkenyl, or heteroaryl ring; R z is R 2a, R 2b1, R 2b2, R 2c, R 2d1, R 2d2, R 2h, R 2i, and R 2j are each independently selected from the group consisting of H, halo, -OH, -CN, -NR c R d, alkyl, alkenyl, alkynyl, -O-alkyl, haloalkyl, cycloalkyl, and -C NR c R d; R 2e, R 2f, R 2g1, and R 2g2 are each independently selected from the group consisting of halo, -OH, -CN, -NR c R d, alkyl, alkenyl, alkynyl, -O-alkyl, haloalkyl, cycloalkyl, and - C NR c R d; and R c and R d are each independently H or alkyl; wherein, when Y 1 is, at least one of (a)-(c) applies: (a) R 2 is -CH 3; (b) R 1 is halo; and (c) G 1 is -C(R b)-, wherein R b is halo; and when Y 1 is and Y 2 is R 2b1 is selected from the group consisting of H, halo, -OH, -CN, -NR c R d, alkyl, alkenyl, alkynyl, -O-C 2 -C 6 alkyl, haloalkyl, cycloalkyl, and -C NR c R d. R 1 is H or halo; G 1 is -N- or -C(R b)-, wherein R b is H or halo, or R b is taken together with R 2 and the atoms to which they are attached to form a 5- or 6-membered cycloalkyl or heterocycloalkyl ring; R 2 is H or -CH 3, or R 2 is taken together with R b and the atoms to which they are attached to form a 5- or 6-membered cycloalkyl or heterocycloalkyl ring; L 1, Y 1, and Y 2 are defined by (i) or (ii): (i) L 1 is absent; Y 1 is R x; and Y 2 is R z; or (ii) L 1 is wherein L 2 is absent, -O-, -NH-, or -OCH 2 - ∗, and wherein ∗ indicates the attachment to Y 2; Y 1 is wherein R 1aa is H, alkyl, cycloalkyl, cycloalkenyl, heterocycloalkyl, heterocycloalkenyl, aryl, or heteroaryl; and Y 2 is -CH 3, phenyl, or R z; (i) L 1 is absent; Y 1 is R x; and Y 2 is R z; or Y 1 is R x; and Y 2 is R z; or (ii) L 1 is wherein L 2 is absent, -O-, -NH-, or -OCH 2 - ∗, and wherein ∗ indicates the attachment to Y 2; Y 1 is wherein R 1aa is H, alkyl, cycloalkyl, cycloalkenyl, heterocycloalkyl, heterocycloalkenyl, aryl, or heteroaryl; and Y 2 is -CH 3, phenyl, or R z; Y 1 is wherein R 1aa is H, alkyl, cycloalkyl, cycloalkenyl, heterocycloalkyl, heterocycloalkenyl, aryl, or heteroaryl; and Y 2 is -CH 3, phenyl, or R z; R x is R 1a, R 1b, R 1c1, R 1c2, R 1f, R 1g, R 1h1, and R 1h2 are each independently H, alkyl, alkenyl, alkynyl, haloalkyl, -C O-alkyl, cycloalkyl, cycloalkenyl, cycloalkynyl, heterocycloalkyl, heterocycloalkenyl, aryl, or heteroaryl; R 1d1, R 1d2, and R 1d3 are each independently alkyl, alkenyl, alkynyl, haloalkyl, -C O-alkyl, cycloalkyl, cycloalkenyl, cycloalkynyl, heterocycloalkyl, heterocycloalkenyl, aryl, or heteroaryl; R 1e1 and R 1e2 are each independently H, alkyl, alkenyl, alkynyl, haloalkyl, -C O-alkyl, or a cycloalkyl, cycloalkenyl, cycloalkynyl, heterocycloalkyl, heterocycloalkenyl, or heteroaryl ring; R z is R 2a, R 2b1, R 2b2, R 2c, R 2d1, R 2d2, R 2h, R 2i, and R 2j are each independently selected from the group consisting of H, halo, -OH, -CN, -NR c R d, alkyl, alkenyl, alkynyl, -O-alkyl, haloalkyl, cycloalkyl, and -C NR c R d; R 2e, R 2f, R 2g1, and R 2g2 are each independently selected from the group consisting of halo, -OH, -CN, -NR c R d, alkyl, alkenyl, alkynyl, -O-alkyl, haloalkyl, cycloalkyl, and - C NR c R d; and R c and R d are each independently H or alkyl; wherein, when Y 1 is, at least one of (a)-(c) applies: (a) R 2 is -CH 3; (b) R 1 is halo; and (c) G 1 is -C(R b)-, wherein R b is halo; and (a) R 2 is -CH 3; (b) R 1 is halo; and (c) G 1 is -C(R b)-, wherein R b is halo; and when Y 1 is and Y 2 is R 2b1 is selected from the group consisting of H, halo, -OH, -CN, -NR c R d, alkyl, alkenyl, alkynyl, -O-C 2 -C 6 alkyl, haloalkyl, cycloalkyl, and -C NR c R d.