A system for removing debris from one or more distal airways of a patient and for cleaning an endotracheal tube, the system comprising: a distal airway cleaning device comprising: a suction catheter having a main suction lumen and a distal end configured to facilitate steering of the suction catheter; and an endotracheal cleaning device comprising: an elongated member having a proximal end and a tip along its distal end, such that the elongated member comprises at least one lumen extending within its interior along at least a portion of length of the elongated member; an expandable structure positioned along the elongated member, wherein the structure is adapted to be selectively moved between a radially-collapsed position and a radially-expanded position; one or more removal members (187A, 187B, 187C, 187D) configured to contact and remove debris collected on an interior surface of the endotracheal tube when the endotracheal cleaning device is moved relative to the endotracheal tube; and a visualization channel configured to removably receive a visualization scope, wherein the visualization channel comprises a transparent or a substantially transparent window at its distal end. a distal airway cleaning device comprising: a suction catheter having a main suction lumen and a distal end configured to facilitate steering of the suction catheter; and an endotracheal cleaning device comprising: an elongated member having a proximal end and a tip along its distal end, such that the elongated member comprises at least one lumen extending within its interior along at least a portion of length of the elongated member; an expandable structure positioned along the elongated member, wherein the structure is adapted to be selectively moved between a radially-collapsed position and a radially-expanded position; one or more removal members (187A, 187B, 187C, 187D) configured to contact and remove debris collected on an interior surface of the endotracheal tube when the endotracheal cleaning device is moved relative to the endotracheal tube; and a visualization channel configured to removably receive a visualization scope, a suction catheter having a main suction lumen and a distal end configured to facilitate steering of the suction catheter; and an endotracheal cleaning device comprising: an elongated member having a proximal end and a tip along its distal end, such that the elongated member comprises at least one lumen extending within its interior along at least a portion of length of the elongated member; an expandable structure positioned along the elongated member, wherein the structure is adapted to be selectively moved between a radially-collapsed position and a radially-expanded position; one or more removal members (187A, 187B, 187C, 187D) configured to contact and remove debris collected on an interior surface of the endotracheal tube when the endotracheal cleaning device is moved relative to the endotracheal tube; and a visualization channel configured to removably receive a visualization scope, an elongated member having a proximal end and a tip along its distal end, such that the elongated member comprises at least one lumen extending within its interior along at least a portion of length of the elongated member; an expandable structure positioned along the elongated member, wherein the structure is adapted to be selectively moved between a radially-collapsed position and a radially-expanded position; one or more removal members (187A, 187B, 187C, 187D) configured to contact and remove debris collected on an interior surface of the endotracheal tube when the endotracheal cleaning device is moved relative to the endotracheal tube; and a visualization channel configured to removably receive a visualization scope, wherein the visualization channel comprises a transparent or a substantially transparent window at its distal end.