A compound of formula II shown below: wherein: R 1, R 4, R 6 and R 7 are each independently selected from the group consisting of H, alkyl, alkyl- R 10, aryl, aryl-R 10, aralkyl, aralkyl-R 11, halogen, NO 2, CN, CF 3, OH, O-alkyl, COR 10, COOR 10, O-aryl, OR 10,NH 2, NH-alkyl, NH-aryl, N-(alkyl) 2, N-(aryl) 2, N-(alkyl)(aryl), NH-R 10, N-(R 10)(R 11), N-(alkyl)(R 10), N-(aryl)(R 10), COOH, CONH 2, CONH-alkyl, CONH-aryl, CON-(alkyl)(R 10), CON(aryl)(R 10), CONH-R 10, CON-(R 10)(R 11), SO 3 H, SO 2 -alkyl, SO 2 -alkyl-R 10, SO 2 -aryl, SO 2 -aryl-R 10, SO 2 NH 2, SO 2 NH-R 10, SO 2 N-(R 10)(R 11), CF 3, CO-alkyl, CO-alkyl-R 10, CO-aryl, CO-aryl-R 10 and R 12, wherein said alkyl, aryl and aralkyl groups may be optionally substituted with one or more groups selected from halogen, CN, OH, O-methyl, NH 2, COOH, CONH 2 and CF 3; R 2 is C 1-3 alkyl; R 3 is H, C 1-6 alkyl, CN or halogen; R 5 is selected from alkyl, alkyl- R 10, aryl, aryl-R 10, aralkyl, aralkyl-R 11, halogen, NO 2, CN, CF 3, OH, O-alkyl, COR 10, COOR 10, O-aryl, O-R 10, NH 2, NH-alkyl, NH-aryl, N-(alkyl) 2, N-(aryl) 2, N-(alkyl)(aryl), NH-R 10, N-(R 10)(R 11), N-(alkyl)(R 10), N-(aryl)(R 10), SH-alkyl, SH-aryl, S-(alkyl) 2, S-(aryl) 2, S-(alkyl)(aryl), SH-R 10, S-(R 10)(R 11), S-(alkyl)(R 10), S-(aryl)(R 10), COOH, CONH 2, CONH-alkyl, CONH-aryl, CON-(alkyl)(R 10), CON(aryl)(R 10), CONH-R 10, CON-(R 10)(R 11), SO 3 H, SO 2 -alkyl, SO 2 -alkyl-R 10, SO 2 -aryl, SO 2 -aryl-R 10, SO 2 NH 2, SO 2 NH-R 10, SO 2 N-(R 10)(R 11), CF 3, CO-alkyl, CO-alkyl-R 10, CO-aryl, CO-aryl-R 10 and R 12, wherein said alkyl, aryl and aralkyl groups may be optionally substituted with one or more groups selected from halogen, CN, OH, O-methyl, NH 2, COOH, CONH 2 and CF 3; R 10, R 11 and R 12 are independently selected from the group of water solubilising groups consisting of: mono-, di- and poly-hydroxylated alicyclic groups, di- or poly-hydroxylated aliphatic or aryl groups, N-, O- and/or S-containing heterocyclic groups substituted with one or more hydroxyl or amino groups, aliphatic and aryl groups comprising one or more carboxamide, sulfoxide, sulfone or sulfonamide groups, and halogenated alkylcarbonyl groups, and COOH, SO 3 H, OSO 3 H, PO 3 H 2 and OPO 3 H 2, except when R 5 and/or R 6 is R 12, in which case R 12 is selected from the group of water solubilising groups consisting of: mono-, di- and poly-hydroxylated alicyclic groups, di- or poly-hydroxylated aliphatic or aryl groups, N-, O- and/or S-containing heterocyclic groups substituted with one or more hydroxyl or amino groups, aliphatic and aryl groups comprising one or more carboxamide, sulfoxide, sulfone or sulfonamide groups, and halogenated alkylcarbonyl groups, COOH, SO 3 H, OSO 3 H, PO 3 H 2 and OPO 3 H 2, and the following groups: or a pharmaceutically acceptable salt or solvate thereof. R 1, R 4, R 6 and R 7 are each independently selected from the group consisting of H, alkyl, alkyl- R 10, aryl, aryl-R 10, aralkyl, aralkyl-R 11, halogen, NO 2, CN, CF 3, OH, O-alkyl, COR 10, COOR 10, O-aryl, OR 10,NH 2, NH-alkyl, NH-aryl, N-(alkyl) 2, N-(aryl) 2, N-(alkyl)(aryl), NH-R 10, N-(R 10)(R 11), N-(alkyl)(R 10), N-(aryl)(R 10), COOH, CONH 2, CONH-alkyl, CONH-aryl, CON-(alkyl)(R 10), CON(aryl)(R 10), CONH-R 10, CON-(R 10)(R 11), SO 3 H, SO 2 -alkyl, SO 2 -alkyl-R 10, SO 2 -aryl, SO 2 -aryl-R 10, SO 2 NH 2, SO 2 NH-R 10, SO 2 N-(R 10)(R 11), CF 3, CO-alkyl, CO-alkyl-R 10, CO-aryl, CO-aryl-R 10 and R 12, wherein said alkyl, aryl and aralkyl groups may be optionally substituted with one or more groups selected from halogen, CN, OH, O-methyl, NH 2, COOH, CONH 2 and CF 3; R 2 is C 1-3 alkyl; R 3 is H, C 1-6 alkyl, CN or halogen; R 5 is selected from alkyl, alkyl- R 10, aryl, aryl-R 10, aralkyl, aralkyl-R 11, halogen, NO 2, CN, CF 3, OH, O-alkyl, COR 10, COOR 10, O-aryl, O-R 10, NH 2, NH-alkyl, NH-aryl, N-(alkyl) 2, N-(aryl) 2, N-(alkyl)(aryl), NH-R 10, N-(R 10)(R 11), N-(alkyl)(R 10), N-(aryl)(R 10), SH-alkyl, SH-aryl, S-(alkyl) 2, S-(aryl) 2, S-(alkyl)(aryl), SH-R 10, S-(R 10)(R 11), S-(alkyl)(R 10), S-(aryl)(R 10), COOH, CONH 2, CONH-alkyl, CONH-aryl, CON-(alkyl)(R 10), CON(aryl)(R 10), CONH-R 10, CON-(R 10)(R 11), SO 3 H, SO 2 -alkyl, SO 2 -alkyl-R 10, SO 2 -aryl, SO 2 -aryl-R 10, SO 2 NH 2, SO 2 NH-R 10, SO 2 N-(R 10)(R 11), CF 3, CO-alkyl, CO-alkyl-R 10, CO-aryl, CO-aryl-R 10 and R 12, wherein said alkyl, aryl and aralkyl groups may be optionally substituted with one or more groups selected from halogen, CN, OH, O-methyl, NH 2, COOH, CONH 2 and CF 3; R 10, R 11 and R 12 are independently selected from the group of water solubilising groups consisting of: mono-, di- and poly-hydroxylated alicyclic groups, di- or poly-hydroxylated aliphatic or aryl groups, N-, O- and/or S-containing heterocyclic groups substituted with one or more hydroxyl or amino groups, aliphatic and aryl groups comprising one or more carboxamide, sulfoxide, sulfone or sulfonamide groups, and halogenated alkylcarbonyl groups, and COOH, SO 3 H, OSO 3 H, PO 3 H 2 and OPO 3 H 2, except when R 5 and/or R 6 is R 12, in which case R 12 is selected from the group of water solubilising groups consisting of: mono-, di- and poly-hydroxylated alicyclic groups, di- or poly-hydroxylated aliphatic or aryl groups, N-, O- and/or S-containing heterocyclic groups substituted with one or more hydroxyl or amino groups, aliphatic and aryl groups comprising one or more carboxamide, sulfoxide, sulfone or sulfonamide groups, and halogenated alkylcarbonyl groups, COOH, SO 3 H, OSO 3 H, PO 3 H 2 and OPO 3 H 2, and the following groups: or a pharmaceutically acceptable salt or solvate thereof.