mhurhangee/ep-ind-claims huggingface dataset:
A method of predicting a response of a subject to CD19 chimeric antigen receptor T cell (CAR-T cell) treatment of a hematological cancer comprising CD19 expressing cancer cells, the method comprising measuring a baseline Sum of Product Diameters of Index Lesions of the subject, determining the SPD range, wherein the SPD can fall within one of four ranges, wherein the four ranges comprise: SPD Quartile 1: from 100 to 2000 mm 2, median SPD of about 840; SPD Quartile 2: from more than 2000 to 3700 mm 2, median SPD of about 2820; SPD Quartile 3: from more than 3700 to 6700 mm 2, median SPD of about 5100; and SPD Quartile 4: from more than 6700 to 24,000 mm 2, median SPD of about 9300, wherein the subject is predicted to respond to a CD19 CAR-T treatment, when the SPD value of the subject falls within SPD Quartile 1 or SPD Quartile 2. measuring a baseline Sum of Product Diameters of Index Lesions of the subject, determining the SPD range, wherein the SPD can fall within one of four ranges, wherein the four ranges comprise: SPD Quartile 1: from 100 to 2000 mm 2, median SPD of about 840; SPD Quartile 2: from more than 2000 to 3700 mm 2, median SPD of about 2820; SPD Quartile 3: from more than 3700 to 6700 mm 2, median SPD of about 5100; and SPD Quartile 4: from more than 6700 to 24,000 mm 2, median SPD of about 9300, SPD Quartile 1: from 100 to 2000 mm 2, median SPD of about 840; SPD Quartile 2: from more than 2000 to 3700 mm 2, median SPD of about 2820; SPD Quartile 3: from more than 3700 to 6700 mm 2, median SPD of about 5100; and SPD Quartile 4: from more than 6700 to 24,000 mm 2, median SPD of about 9300, wherein the subject is predicted to respond to a CD19 CAR-T treatment, when the SPD value of the subject falls within SPD Quartile 1 or SPD Quartile 2.
Allopregnanolone for use in a method of treating postpartum depression in a human subject, the method comprising administering a continuous intravenous infusion, wherein the infusion comprises administering a first infusion, second infusion, and third infusion to the subject, and wherein the first (step-up) infusion delivers a smaller amount of allopregnanolone/unit time than the second (maintenance) infusion and wherein the third (step-down/downward taper) infusion delivers a smaller amount of allopregnanolone /unit time than the second (maintenance) infusion.
A device (1, 1') for applying adhesive and/or sealant, comprising a housing for receiving a container, the housing comprising: - a receiving space for receiving the container; - a closable application tip which is connected to the receiving space and through which the adhesive and/or sealant can exit; - a stable casing for the receiving space; - at least one region of the housing which is designed as a deformable pressure region and which allows for an exertion of pressure from the outside on the container which can be arranged in the receiving space, the pressure region having at least one movable region which is separated from the remaining housing surrounding said movable region by a zone having increased deformability, characterized in that the zone having increased deformability is designed in that the material of the pressure region is inserted therein in such a way that it is turned out when the movable region is pressed in and allows for movement of the movable region against the remaining housing surrounding said movable region. - a receiving space for receiving the container; - a closable application tip which is connected to the receiving space and through which the adhesive and/or sealant can exit; - a stable casing for the receiving space; - at least one region of the housing which is designed as a deformable pressure region and which allows for an exertion of pressure from the outside on the container which can be arranged in the receiving space, the pressure region having at least one movable region which is separated from the remaining housing surrounding said movable region by a zone having increased deformability, characterized in that the zone having increased deformability is designed in that the material of the pressure region is inserted therein in such a way that it is turned out when the movable region is pressed in and allows for movement of the movable region against the remaining housing surrounding said movable region.
A turbojet engine fan blade, the fan blade having a radially inner extremity and a radially outer extremity, the fan blade comprising: a blade root defining the radially inner extremity, and a blade tip defining the radially outer extremity, characterised by: a platform located between the blade root and a body of the blade, the platform having an axially protruding end; a leading edge extending radially between the extremities; and a sheath extending continuously over the leading edge and the axially protruding end from the blade root to the blade tip. a platform located between the blade root and a body of the blade, the platform having an axially protruding end; a leading edge extending radially between the extremities; and a sheath extending continuously over the leading edge and the axially protruding end from the blade root to the blade tip.
Refrigeration device having an interior in which a shelf is arranged, wherein a tray supported in a displaceable manner on rollers is arranged on the shelf, characterised in that the shelf has two guide rails on two opposing longitudinal sides, wherein the guide rails have guide surfaces which cooperate with roller side walls of the rollers.
A lighting device comprising: - a housing and multiple light sources arranged in the housing, the light sources emitting light of a first wavelength range; - a wavelength converting member arranged at a distance from said light sources, said wavelength converting member comprising a first wavelength converting material configured to convert a part of said light of a first wavelength range into light of a second wavelength range; and - a color distribution member providing a color distribution of the light emitted from the lighting device where the ratio of intensity of light with the first wavelength range to the intensity of light with the second wavelength range is larger at low angles to a light output surface of the lighting device than at high angles to the light output surface, characterized in that the color distribution member comprises a light redirecting element, arranged between the light sources and the wavelength converting member, which redirects incoming light from the light sources reaching the light redirecting element at an angle of incidence to outgoing light leaving the light redirecting element at a lower angle than the angle of incidence. - a housing and multiple light sources arranged in the housing, the light sources emitting light of a first wavelength range; - a wavelength converting member arranged at a distance from said light sources, said wavelength converting member comprising a first wavelength converting material configured to convert a part of said light of a first wavelength range into light of a second wavelength range; and - a color distribution member providing a color distribution of the light emitted from the lighting device where the ratio of intensity of light with the first wavelength range to the intensity of light with the second wavelength range is larger at low angles to a light output surface of the lighting device than at high angles to the light output surface,
A wrist-worn physical activity measurement apparatus comprising: a bracelet comprising a plurality of links; a flexible casing encasing the plurality of the links; one or more physical activity measurement sensors (702, 724); and an electronics module (300, 404; 600, 602, 604, 606, 608, 610, 612) coupled with the bracelet; wherein the apparatus is attachable around a curvature of a wrist of a user such that the links and the adjacent links are pivotably lockable in relation to each other in order to wrap and lock around the wrist; characterized in that each link is formed at one side to comprise a part and at the opposite side a counterpart interlocking with a part of an adjacent link. a bracelet comprising a plurality of links; a flexible casing encasing the plurality of the links; one or more physical activity measurement sensors (702, 724); and an electronics module (300, 404; 600, 602, 604, 606, 608, 610, 612) coupled with the bracelet; wherein the apparatus is attachable around a curvature of a wrist of a user such that the links and the adjacent links are pivotably lockable in relation to each other in order to wrap and lock around the wrist; characterized in that each link is formed at one side to comprise a part and at the opposite side a counterpart interlocking with a part of an adjacent link.
An optical polyester film comprising: a base material comprising a polyester resin comprising a unit of the following formula; and at least one functional layer disposed on at least one surface of the base material, wherein the at least one functional layer is selected from the group consisting of a hard coat layer, a transparent conductive layer, an anti-reflection layer, a gas barrier layer, and an adhesive layer: wherein R 1 is a hydrogen atom, CH 3, or C 2 H 5, R 2 and R 3 are each independently a hydrogen atom or CH 3, and n is 1. a base material comprising a polyester resin comprising a unit of the following formula; and at least one functional layer disposed on at least one surface of the base material, wherein the at least one functional layer is selected from the group consisting of a hard coat layer, a transparent conductive layer, an anti-reflection layer, a gas barrier layer, and an adhesive layer: wherein R 1 is a hydrogen atom, CH 3, or C 2 H 5, R 2 and R 3 are each independently a hydrogen atom or CH 3, and n is 1.
A depth camera configured to emit infrared light to image a physical space, comprising: an infrared light source to emit infrared light into a physical space; an infrared camera to receive infrared light from the physical space; an imaging interface to output a depth map derived from the received infrared light; and a control interface configured to receive an instruction indicating that an infrared remote control signal command for causing an action to be performed by an external device is to be emitted from the infrared light source, wherein the infrared light source is configured to emit the infrared remote control signal command responsive to the control interface receiving the instruction. an infrared light source to emit infrared light into a physical space; an infrared camera to receive infrared light from the physical space; an imaging interface to output a depth map derived from the received infrared light; and a control interface configured to receive an instruction indicating that an infrared remote control signal command for causing an action to be performed by an external device is to be emitted from the infrared light source, wherein the infrared light source is configured to emit the infrared remote control signal command responsive to the control interface receiving the instruction.
Method for controlling a plurality of hover-capable aircraft (2; 2.1-2.4), preferably vertical take-off and landing multicopters having a plurality of spaced-apart, electrically driven rotors, during transportation of a load, which load is carried jointly by all aircraft (2; 2.1-2.4) by means of at least one flexible element (3; 3.1-3.4) for each aircraft, wherein an attitude and/or a position of the load is altered by altering a length of at least one of the flexible elements (3; 3.1-3.4); characterized in that the attitude and/or position of the load is altered while keeping the attitude and altitude of the plurality of aircraft (2; 2.1-2.4) essentially constant.
An integrated device for improving the visual system of a human subject having an eye, a head, and a skull, the device comprising: - a computer in data communication with a display, the computer and display adapted to present optical stimuli to a targeted region of an eye, the computer including a timer for measuring a time relationship; - a current source having at least one connector for connection of at least one electrode assembly (220, 230), - wherein the current source provides electrical stimulation to the subject's brain and the display provides optical stimulation to the subject's visual system in the time relationship, wherein the time relationship includes providing the electrical stimulation prior to, concurrent with or subsequent to the optical stimulation, characterized by a housing adapted to contain the current source in combination with at least one of the display and the computer, wherein the computer is adapted to control the current source such that specific current limits and specific coulomb limits for exposure of the human subject over an established period of time are not exceeded. - a computer in data communication with a display, the computer and display adapted to present optical stimuli to a targeted region of an eye, the computer including a timer for measuring a time relationship; - a current source having at least one connector for connection of at least one electrode assembly (220, 230), - wherein the current source provides electrical stimulation to the subject's brain and the display provides optical stimulation to the subject's visual system in the time relationship,
A method for controlling communication with a communication device connected to a plurality of access points, the method comprising determining predefined inactivity related to expiration of an inactivity timer in communications between a first access point and the communication device, receiving an indication of predefined inactivity in communications between the communication device and a second access point, and changing the connectivity state of the communication device when said predefined inactivity in communications between the first access point and the communication device has been determined and said indication has been received.
Sensor structure (16, 16') for online monitoring of levels of Furans in oil of a transformer tank, the sensor structure (16, 16') being characterized in comprising: an ultraviolet light source, a filter permitting only ultraviolet light of a certain wavelength range to pass the filter, a transparent window arranged so that the filtered ultraviolet light passes there-through, the window having a passage through which the oil can flow, wherein ultraviolet light is transmitted through a first side of the window, travels through the passage and exits on a second side of the window, and an ultraviolet light detector configured to receive ultraviolet light that passes through the window, wherein, when the sensor structure (16, 16') is mounted with respect to the transformer tank that is online so that the window is exposed to oil, and the Furans in the oil are being monitored, the Furans will absorb ultraviolet light, thus creating a difference in ultraviolet light received by the ultraviolet light detector when compared to the ultraviolet light received by the ultraviolet light detector when the monitored oil has no Furans therein, and wherein the ultraviolet light detector is configured to provide an output signal that is substantially proportional to a total of the Furans in the monitored oil. an ultraviolet light source, a filter permitting only ultraviolet light of a certain wavelength range to pass the filter, a transparent window arranged so that the filtered ultraviolet light passes there-through, the window having a passage through which the oil can flow, wherein ultraviolet light is transmitted through a first side of the window, travels through the passage and exits on a second side of the window, and an ultraviolet light detector configured to receive ultraviolet light that passes through the window, wherein, when the sensor structure (16, 16') is mounted with respect to the transformer tank that is online so that the window is exposed to oil, and the Furans in the oil are being monitored, the Furans will absorb ultraviolet light, thus creating a difference in ultraviolet light received by the ultraviolet light detector when compared to the ultraviolet light received by the ultraviolet light detector when the monitored oil has no Furans therein, and wherein the ultraviolet light detector is configured to provide an output signal that is substantially proportional to a total of the Furans in the monitored oil.
A copper alloy sheet material, having an alloy composition consisting of any one or two of Ni and Co 0.5 to 5.0 mass% in total, Si 0.1 to 1.5 mass%, and optionally at least one selected from the group consisting of Sn, Zn, Ag, Mn, B, P, Mg, Cr, Fe, Ti, Zr, and Hf 0.005 to 2.0 mass% in total, with the balance being copper and unavoidable impurities, having an R value of 1 or greater, which is defined by: R = BR + RDW + W / C + S + B wherein,,,,, and represent an area ratio of crystal texture orientation component of BR orientation {3 6 2} <8 5 3>, RD-rotated-cube orientation {0 1 2} <1 0 0>, cube orientation {1 0 0} <0 0 1>, copper orientation {1 2 1} <1 1 1>, S-orientation {2 3 1} <3 4 6>, and brass orientation {1 1 0} <1 1 2>, respectively, in crystal orientation analysis in an EBSD (electron back scatter diffraction) analysis, and having a proof stress of 500 MPa or greater, and an electrical conductivity of 30%IACS or higher.
A prosthetic valve, preferably an expandable prosthetic valve, having a valve component, preferably a mitral valve component, made of a single functional leaflet wherein the prosthetic valve comprises at least two tissue supports (4', 4",4"',4"") attachable to an inner surface of a stent component, wherein at least one tissue support (4', 4",4"',4"") comprises at least one attachment area (7', 7"), at least a section of the attachment area extending essentially inwardly from the inner surface, wherein said leaflet is attached to at least one tissue support (4', 4",4"',4"') at the section of said attachment area(s) (7', 7") such that the leaflet is arranged between said attachment area(s) (7', 7") or integrally formed with one tissue support (4',4",4"',4"") and attached to the second tissue support (4',4",4'",4"") at the section of the attachment area(s) (7', 7").
An embossing tool for deforming smooth and embossed films made of metal or films made of laminates of metal and plastics, wherein the embossing tool is formed to be integratable into a stamping and embossing machine and comprises a matrix with an embossing region and a patrix to emboss a film which is guidable or placeable between the matrix and patrix, wherein an embossing structure is applied to the bottom side of the matrix by elevations, characterized - in that, above the matrix, a first compensating element is arranged and an upper receiving plate is arranged above that, - in that, in the receiving plate, a recess is formed at the bottom side thereof, in which recess the compensating element is inserted, wherein the compensating element projects beyond the recess by a few tenths of a millimeter and lies at the back side of the matrix directly behind the elevations for the embossing, and - in that, in a mirror-image manner to the matrix at the patrix on the surface of which an elevation with the embossing pattern is formed, a second, elastically deformable compensating element is arranged in a recess in a lower receiving plate and projects beyond the receiving plate. - in that, above the matrix, a first compensating element is arranged and an upper receiving plate is arranged above that, - in that, in the receiving plate, a recess is formed at the bottom side thereof, in which recess the compensating element is inserted, wherein the compensating element projects beyond the recess by a few tenths of a millimeter and lies at the back side of the matrix directly behind the elevations for the embossing, and - in that, in a mirror-image manner to the matrix at the patrix on the surface of which an elevation with the embossing pattern is formed, a second, elastically deformable compensating element is arranged in a recess in a lower receiving plate and projects beyond the receiving plate.
Luminaire comprising a housing having a light-emitting opening for emitting light and a transparent light-emitting element for covering the light exit opening, wherein the housing comprises a holding element for holding the light-emitting element on the housing, and wherein the luminaire is so formed that the holding element can be moved freely back and forth between a holding position in which it holds the light-emitting element on the housing and a released position in which it releases the light-emitting element so that it can be separated directly from the housing, wherein a supporting unit is provided on the rest of the housing for the movable support of the holding element characterised in that the supporting unit is so designed that the holding element for movement from the holding position to the released position, first moves rectilinearly along an axis with respect to the rest of the housing and can then be rotated about the axis.
A survey and navigation metrology device, comprising: at least one sensor string segment; at least three centralizers; at least one metrology sensor; and at least one odometry sensor, wherein the at least three centralizers are for supporting said string segment, said at least three centralizers including a middle centralizer and at least two other centralizers (14b, 14c); the at least one metrology sensor is for measuring displacement of said string segment relative to said middle centralizer, and for generating metrology information corresponding to said displacement, said metrology sensor being associated with said middle centralizer and being located between said at least two other centralizers, and wherein said displacement of said string segment relative to said middle centralizer is caused by relative movement of said at least two other centralizers; and the at least one odometry sensor is for generating odometry information for determining, together with said displacement information, the position of said sensor string segment. at least one sensor string segment; at least three centralizers; at least one metrology sensor; and at least one odometry sensor, wherein the at least three centralizers are for supporting said string segment, said at least three centralizers including a middle centralizer and at least two other centralizers (14b, 14c); the at least one metrology sensor is for measuring displacement of said string segment relative to said middle centralizer, and for generating metrology information corresponding to said displacement, said metrology sensor being associated with said middle centralizer and being located between said at least two other centralizers, and wherein said displacement of said string segment relative to said middle centralizer is caused by relative movement of said at least two other centralizers; and the at least one odometry sensor is for generating odometry information for determining, together with said displacement information, the position of said sensor string segment.