A portable clinical system for in vitro analysis, the system comprising: an analyzer comprising: a port configured to receive a test device; and a computing device comprising at least one accelerometer, wherein the computing device is configured to: determine a spatial orientation of the analyzer and measure dynamic acceleration to determine motion of the analyzer; determine that the analyzer is in free fall based on the at least one accelerometer sensing the free fall as a predetermined value or was in free fall followed by a subsequent impact based on the at least one accelerometer sensing the free fall as the predetermined value and a sudden change in rate of acceleration after the free fall as the subsequent impact; lock the analyzer from performing an analytical test using the test device, when the analyzer is determined to be in the free fall or have been in the free fall followed by the subsequent impact; provide a first time-stamp of when the analyzer is locked; provide an alert prompting a user that a system performance verification is required to unlock the analyzer; perform a system performance verification; provide a second time-stamp of when the system performance verification is performed; and, store the first time-stamp and the second time-stamp in an electronic auditable system. a port configured to receive a test device; and a computing device comprising at least one accelerometer, wherein the computing device is configured to: determine a spatial orientation of the analyzer and measure dynamic acceleration to determine motion of the analyzer; determine that the analyzer is in free fall based on the at least one accelerometer sensing the free fall as a predetermined value or was in free fall followed by a subsequent impact based on the at least one accelerometer sensing the free fall as the predetermined value and a sudden change in rate of acceleration after the free fall as the subsequent impact; lock the analyzer from performing an analytical test using the test device, when the analyzer is determined to be in the free fall or have been in the free fall followed by the subsequent impact; provide a first time-stamp of when the analyzer is locked; provide an alert prompting a user that a system performance verification is required to unlock the analyzer; perform a system performance verification; provide a second time-stamp of when the system performance verification is performed; and, store the first time-stamp and the second time-stamp in an electronic auditable system. determine a spatial orientation of the analyzer and measure dynamic acceleration to determine motion of the analyzer; determine that the analyzer is in free fall based on the at least one accelerometer sensing the free fall as a predetermined value or was in free fall followed by a subsequent impact based on the at least one accelerometer sensing the free fall as the predetermined value and a sudden change in rate of acceleration after the free fall as the subsequent impact; lock the analyzer from performing an analytical test using the test device, when the analyzer is determined to be in the free fall or have been in the free fall followed by the subsequent impact; provide a first time-stamp of when the analyzer is locked; provide an alert prompting a user that a system performance verification is required to unlock the analyzer; perform a system performance verification; provide a second time-stamp of when the system performance verification is performed; and, store the first time-stamp and the second time-stamp in an electronic auditable system.