A handle assembly for a left atrial appendage occlusion device delivery system comprising: a first non-rotating catheter displacement component rotatably connected to a second rotatable catheter displacement component, said first non-rotating catheter displacement component having a distal end adapted to operably connect to a delivery catheter for a left atrial appendage occlusion device, wherein the first non-rotating catheter displacement component and the second rotatable catheter displacement component further comprise a lumen therethrough, further wherein the second rotatable catheter displacement component portion of the lumen comprises an internally threaded segment; a first manipulation segment having an externally threaded tubular distal extension adapted to rotationally engage the internally threaded segment of the second rotatable catheter displacement component, said externally threaded tubular distal extension having a length; and a second manipulation segment reversibly coupled to the first manipulation segment, wherein the second manipulation segment has affixed thereto an elongate shaft adapted to slidably and rotatably pass through a lumen associated with the first manipulation segment, the lumen of the first non-rotating catheter displacement component and second rotatable catheter displacement component, and a connected delivery catheter for a left atrial appendage occlusion device, further wherein rotation of the second rotatable catheter displacement component relative to the first non-rotating catheter displacement component is adapted to displace the delivery catheter proximally relative to the elongate shaft by a distance at least equal to the length of the externally threaded tubular distal extension of the first manipulation segment, wherein the lumen of the first non-rotating catheter displacement component and second rotatable catheter displacement component is sized and adapted to slidably receive the externally threaded tubular distal extension of the first manipulation segment in a region distal of the internally threaded segment of the second rotatable catheter displacement component, characterized in that the first manipulation segment having an externally threaded tubular distal extension further comprises a tubular segment affixed to a proximal end of the externally threaded tubular distal extension, said tubular segment being sized and adapted to be slidably received within the internally threaded segment of the second rotatable catheter displacement component. a first non-rotating catheter displacement component rotatably connected to a second rotatable catheter displacement component, said first non-rotating catheter displacement component having a distal end adapted to operably connect to a delivery catheter for a left atrial appendage occlusion device, wherein the first non-rotating catheter displacement component and the second rotatable catheter displacement component further comprise a lumen therethrough, further wherein the second rotatable catheter displacement component portion of the lumen comprises an internally threaded segment; a first manipulation segment having an externally threaded tubular distal extension adapted to rotationally engage the internally threaded segment of the second rotatable catheter displacement component, said externally threaded tubular distal extension having a length; and a second manipulation segment reversibly coupled to the first manipulation segment, wherein the second manipulation segment has affixed thereto an elongate shaft adapted to slidably and rotatably pass through a lumen associated with the first manipulation segment, the lumen of the first non-rotating catheter displacement component and second rotatable catheter displacement component, and a connected delivery catheter for a left atrial appendage occlusion device, further wherein rotation of the second rotatable catheter displacement component relative to the first non-rotating catheter displacement component is adapted to displace the delivery catheter proximally relative to the elongate shaft by a distance at least equal to the length of the externally threaded tubular distal extension of the first manipulation segment, wherein the lumen of the first non-rotating catheter displacement component and second rotatable catheter displacement component is sized and adapted to slidably receive the externally threaded tubular distal extension of the first manipulation segment in a region distal of the internally threaded segment of the second rotatable catheter displacement component, characterized in that the first manipulation segment having an externally threaded tubular distal extension further comprises a tubular segment affixed to a proximal end of the externally threaded tubular distal extension, said tubular segment being sized and adapted to be slidably received within the internally threaded segment of the second rotatable catheter displacement component.