A method of preparing a water-based anti-acne gel comprising: mixing deionized water and hydroxyethylcellulose to obtain a first mixture; applying heat to the first mixture until the first mixture reaches about 75 degrees Celsius; adding disodium ethylenediaminetetraacetic acid (EDTA) and sodium pyrrolidone carboxylic acid to the first mixture and mixing to obtain a second mixture; allowing the second mixture to cool to from 60 to 65 degrees Celsius; mixing butylene glycol and salicylic acid to obtain a third mixture; applying heat to the third mixture until the third mixture reaches about 65 degrees Celsius; mixing the third mixture and second mixture together to obtain a fourth mixture; allowing the fourth mixture to cool to from 55 to 60 degrees Celsius; adding glycolic acid and lactic acid to the fourth mixture and mixing to obtain a fifth mixture; allowing the fifth mixture to cool to from 50 to 55 degrees Celsius; mixing deionized water and sodium hydroxide to obtain a sixth mixture; mixing the sixth mixture and the fifth mixture together to obtain a seventh mixture; allowing the seventh mixture to cool to from 45 to 50 degrees Celsius; mixing deionized water and perilla ocymoides leaf extract to obtain an eighth mixture; mixing the eighth mixture and the seventh mixture to obtain a ninth mixture; mixing deionized water and olea europaea fruit extract to obtain a tenth mixture; mixing the tenth mixture and ninth mixture to obtain an eleventh mixture; allowing the eleventh mixture to cool to from 40 to 45 degrees Celsius; adding sodium benzoate to the eleventh mixture and mixing to obtain a twelfth mixture; solubilizing an unsolubilized hydrolyzed Psoralea Corylifolia extract to obtain a solubilized hydrolyzed Psoralea Corylifolia extract comprising mixing the unsolubilized hydrolyzed Psoralea Corylifolia extract, bisabolol, and polysorbate 20 to obtain a thirteenth mixture, and mixing the thirteenth mixture and the twelfth mixture to obtain a fourteenth mixture, wherein the fourteenth mixture comprises the solubilized hydrolyzed Psoralea Corylifolia extract; allowing the fourteenth mixture to cool to 35 degrees Celsius; thereby obtaining an aqueous mixture that is a combination of the twelfth and thirteenth mixtures, wherein the aqueous mixture comprises the water-based, anti-acne gel. mixing deionized water and hydroxyethylcellulose to obtain a first mixture; applying heat to the first mixture until the first mixture reaches about 75 degrees Celsius; adding disodium ethylenediaminetetraacetic acid (EDTA) and sodium pyrrolidone carboxylic acid to the first mixture and mixing to obtain a second mixture; allowing the second mixture to cool to from 60 to 65 degrees Celsius; mixing butylene glycol and salicylic acid to obtain a third mixture; applying heat to the third mixture until the third mixture reaches about 65 degrees Celsius; mixing the third mixture and second mixture together to obtain a fourth mixture; allowing the fourth mixture to cool to from 55 to 60 degrees Celsius; adding glycolic acid and lactic acid to the fourth mixture and mixing to obtain a fifth mixture; allowing the fifth mixture to cool to from 50 to 55 degrees Celsius; mixing deionized water and sodium hydroxide to obtain a sixth mixture; mixing the sixth mixture and the fifth mixture together to obtain a seventh mixture; allowing the seventh mixture to cool to from 45 to 50 degrees Celsius; mixing deionized water and perilla ocymoides leaf extract to obtain an eighth mixture; mixing the eighth mixture and the seventh mixture to obtain a ninth mixture; mixing deionized water and olea europaea fruit extract to obtain a tenth mixture; mixing the tenth mixture and ninth mixture to obtain an eleventh mixture; allowing the eleventh mixture to cool to from 40 to 45 degrees Celsius; adding sodium benzoate to the eleventh mixture and mixing to obtain a twelfth mixture; solubilizing an unsolubilized hydrolyzed Psoralea Corylifolia extract to obtain a solubilized hydrolyzed Psoralea Corylifolia extract comprising mixing the unsolubilized hydrolyzed Psoralea Corylifolia extract, bisabolol, and polysorbate 20 to obtain a thirteenth mixture, and mixing the thirteenth mixture and the twelfth mixture to obtain a fourteenth mixture, wherein the fourteenth mixture comprises the solubilized hydrolyzed Psoralea Corylifolia extract; allowing the fourteenth mixture to cool to 35 degrees Celsius; thereby obtaining an aqueous mixture that is a combination of the twelfth and thirteenth mixtures, wherein the aqueous mixture comprises the water-based, anti-acne gel.