A compound of Formula wherein each R 1 is independently selected from the group consisting of halogen, C 1-3 alkyl and -NH 2 n is 0, 1, 2 or 3 R 10 is selected from the group consisting of hydrogen, halogen, C 1-3 alkyl and -NH 2 R 2 and R 3 is independently selected from the group consisting of hydrogen, halogen, -OH, -C 1-4 alkylene- R q, -N R w R q, -NHC N R w R q, -C N R w R q, -C O R q, -S 2 N R w R q and -N R w S 2 R q or R 2 and R 3 together with the atoms they are attached to form a 5-6 membered heteroaryl optionally substituted by one or more same or different R t R w is selected from the group consisting of hydrogen, C 1-4 alkyl, C 3-6 cycloalkyl, -OH, -OC 1-4 alkyl and -NH 2 R q is selected from the group consisting of hydrogen, C 1-4 alkyl, C 3-6 cycloalkyl, -OH, -OC 1-4 alkyl and -NH 2 R t is selected from the group consisting of C 1-4 alkyl, C 3-6 cycloalkyl, -OH, -OC 1-4 alkyl and -NH 2 R 4 is -N( R x)- or-O- R x is selected from the group consisting of hydrogen, C 1-4 alkyl, -OH, -OC 1-4 alkyl and -C 1-5 alkylene-O- R y1 R y1 is selected from the group consisting of hydrogen, C 1-4 alkyl and -NH 2 R 5 is selected from the group consisting of hydrogen, C 1-4 alkyl, -OH, -OC 1-4 alkyl and -C 1-5 alkylene-O- R y2 R y2 is selected from the group consisting of hydrogen, C 1-4 alkyl and -NH 2 R 6 is hydrogen or C 1-3 alkyl R 7 is selected from the group consisting of -R a -Cy and -R a -R b or R 6 and R 7 together with the nitrogen that they are attached to form a 5-13 membered heterocyclyl or a 5-13 membered heteroaryl, wherein said heterocyclyl or heteroaryl is substituted by one or more same or different R b R a is selected from the group consisting of a covalent bond, -C 1-5 alkylene-and -C 1-3 alkylene- R c -C 1-3 alkylene CH 2 - R c is selected from the group consisting of a covalent bond, arylene, C 5-14 -carbocyclene, 5-13 membered heteroarylene and 5-13 membered heterocyclene Cy is selected from the group consisting of aryl, C 5-14 -carbocyclyl, 5-13 membered heteroaryl and 5-13 membered heterocyclyl; wherein Cy is substituted by -R a1 -R b or -R a1 -Cy' and Cy is optionally further substituted by one or more same or different R b Cy' is selected from the group consisting of aryl, 5-9 membered heteroaryl and 5-9 membered heterocyclyl; wherein Cy' is substituted by one or more same or different R b R a1 is a covalent bond or -C 1-5 salkylene- R b is selected from the group consisting of hydrogen, C 2-3 alkynyl, C 1-4 alkyl, -OH, -OC 1-4 alkyl, -NH 2, -C NH 2 and -C 1-5 alkylene-O-C 1-5 alkyl or a salt thereof. each R 1 is independently selected from the group consisting of halogen, C 1-3 alkyl and -NH 2 n is 0, 1, 2 or 3 R 10 is selected from the group consisting of hydrogen, halogen, C 1-3 alkyl and -NH 2 R 2 and R 3 is independently selected from the group consisting of hydrogen, halogen, -OH, -C 1-4 alkylene- R q, -N R w R q, -NHC N R w R q, -C N R w R q, -C O R q, -S 2 N R w R q and -N R w S 2 R q or R 2 and R 3 together with the atoms they are attached to form a 5-6 membered heteroaryl optionally substituted by one or more same or different R t R w is selected from the group consisting of hydrogen, C 1-4 alkyl, C 3-6 cycloalkyl, -OH, -OC 1-4 alkyl and -NH 2 R q is selected from the group consisting of hydrogen, C 1-4 alkyl, C 3-6 cycloalkyl, -OH, -OC 1-4 alkyl and -NH 2 R t is selected from the group consisting of C 1-4 alkyl, C 3-6 cycloalkyl, -OH, -OC 1-4 alkyl and -NH 2 R 4 is -N( R x)- or-O- R x is selected from the group consisting of hydrogen, C 1-4 alkyl, -OH, -OC 1-4 alkyl and -C 1-5 alkylene-O- R y1 R y1 is selected from the group consisting of hydrogen, C 1-4 alkyl and -NH 2 R 5 is selected from the group consisting of hydrogen, C 1-4 alkyl, -OH, -OC 1-4 alkyl and -C 1-5 alkylene-O- R y2 R y2 is selected from the group consisting of hydrogen, C 1-4 alkyl and -NH 2 R 6 is hydrogen or C 1-3 alkyl R 7 is selected from the group consisting of -R a -Cy and -R a -R b or R 6 and R 7 together with the nitrogen that they are attached to form a 5-13 membered heterocyclyl or a 5-13 membered heteroaryl, wherein said heterocyclyl or heteroaryl is substituted by one or more same or different R b R a is selected from the group consisting of a covalent bond, -C 1-5 alkylene-and -C 1-3 alkylene- R c -C 1-3 alkylene CH 2 - R c is selected from the group consisting of a covalent bond, arylene, C 5-14 -carbocyclene, 5-13 membered heteroarylene and 5-13 membered heterocyclene Cy is selected from the group consisting of aryl, C 5-14 -carbocyclyl, 5-13 membered heteroaryl and 5-13 membered heterocyclyl; wherein Cy is substituted by -R a1 -R b or -R a1 -Cy' and Cy is optionally further substituted by one or more same or different R b Cy' is selected from the group consisting of aryl, 5-9 membered heteroaryl and 5-9 membered heterocyclyl; wherein Cy' is substituted by one or more same or different R b R a1 is a covalent bond or -C 1-5 salkylene- R b is selected from the group consisting of hydrogen, C 2-3 alkynyl, C 1-4 alkyl, -OH, -OC 1-4 alkyl, -NH 2, -C NH 2 and -C 1-5 alkylene-O-C 1-5 alkyl