mhurhangee/ep-ind-claims huggingface dataset:
An isolated T cell receptor specific for MAGE-A4, wherein the TCR comprises: a) a variable TCR α region comprising a CDR1 having the amino acid sequence of SEQ ID NO: 2, a CDR2 having the amino acid sequence of SEQ ID NO: 3 and a CDR3 having the amino acid sequence of SEQ ID NO: 4, a variable TCR β region comprising a CDR1 having the amino acid sequence of SEQ ID NO: 5, a CDR2 having the amino acid sequence of SEQ ID NO: 6 and a CDR3 having the amino acid sequence of SEQ ID NO: 7; or b) a variable TCR α region comprising a CDR1 having the amino acid sequence of SEQ ID NO: 12, a CDR2 having the amino acid sequence of SEQ ID NO: 13 and a CDR3 having the amino acid sequence of SEQ ID NO: 14, a variable TCR β region comprising a CDR1 having the amino acid sequence of SEQ ID NO: 15, a CDR2 having the amino acid sequence of SEQ ID NO: 16 and a CDR3 having the amino acid sequence of SEQ ID NO: 17; or c) a variable TCR α region comprising a CDR1 having the amino acid sequence of SEQ ID NO: 22, a CDR2 having the amino acid sequence of SEQ ID NO: 23 and a CDR3 having the amino acid sequence of SEQ ID NO: 24, a variable TCR β region comprising a CDR1 having the amino acid sequence of SEQ ID NO: 25, a CDR 2 having the amino acid sequence of SEQ ID NO: 26 and a CDR 3 having the amino acid sequence of SEQ ID NO: 27, wherein the TCR specifically recognizes the HLA-A2 bound form of the amino acid sequence of SEQ ID NO: 1. a) a variable TCR α region comprising a CDR1 having the amino acid sequence of SEQ ID NO: 2, a CDR2 having the amino acid sequence of SEQ ID NO: 3 and a CDR3 having the amino acid sequence of SEQ ID NO: 4, a variable TCR β region comprising a CDR1 having the amino acid sequence of SEQ ID NO: 5, a CDR2 having the amino acid sequence of SEQ ID NO: 6 and a CDR3 having the amino acid sequence of SEQ ID NO: 7; or b) a variable TCR α region comprising a CDR1 having the amino acid sequence of SEQ ID NO: 12, a CDR2 having the amino acid sequence of SEQ ID NO: 13 and a CDR3 having the amino acid sequence of SEQ ID NO: 14, a variable TCR β region comprising a CDR1 having the amino acid sequence of SEQ ID NO: 15, a CDR2 having the amino acid sequence of SEQ ID NO: 16 and a CDR3 having the amino acid sequence of SEQ ID NO: 17; or c) a variable TCR α region comprising a CDR1 having the amino acid sequence of SEQ ID NO: 22, a CDR2 having the amino acid sequence of SEQ ID NO: 23 and a CDR3 having the amino acid sequence of SEQ ID NO: 24, a variable TCR β region comprising a CDR1 having the amino acid sequence of SEQ ID NO: 25, a CDR 2 having the amino acid sequence of SEQ ID NO: 26 and a CDR 3 having the amino acid sequence of SEQ ID NO: 27, wherein the TCR specifically recognizes the HLA-A2 bound form of the amino acid sequence of SEQ ID NO: 1.
A method for controlling self-loopback of network data, characterized by comprising: determining whether a master forwarding link and a standby forwarding link of a master node in a network structure both fail or not; and when the master forwarding link and the standby forwarding link of the master node both fail, modifying a forwarding attribute of a standby egress port in a data packet forwarding table of the master node from forwarding through a preset protection link into forwarding through the master forwarding link of the master node; and when the master forwarding link of the master node fails and the standby forwarding link of the master node does not fail, controlling the master node to send a received data packet to a standby node corresponding to the master node through the preset protection link to enable the standby node to forward the received data packet through the standby forwarding link of the master node. determining whether a master forwarding link and a standby forwarding link of a master node in a network structure both fail or not; and when the master forwarding link and the standby forwarding link of the master node both fail, modifying a forwarding attribute of a standby egress port in a data packet forwarding table of the master node from forwarding through a preset protection link into forwarding through the master forwarding link of the master node; and when the master forwarding link of the master node fails and the standby forwarding link of the master node does not fail, controlling the master node to send a received data packet to a standby node corresponding to the master node through the preset protection link to enable the standby node to forward the received data packet through the standby forwarding link of the master node.
An inkjet printing method comprising in order the steps of: a) providing to an inkjet printer two or more colourless liquids and a white ink comprising a pigment with a refractive index greater than 1.60; b) mixing said white ink in a controlled amount with said two or more colourless liquids to form a white ink-mixture wherein the viscosity is reduced by at least 5 mPa.s by reference to the white ink when measuring the viscosity at 40°C with a Brookfield DV-II+Pro at 12 rotations per minute and c) printing the white ink-mixture with the inkjet printer onto an ink-receiver, wherein at least two colourless liquids have a different surface tension. a) providing to an inkjet printer two or more colourless liquids and a white ink comprising a pigment with a refractive index greater than 1.60; b) mixing said white ink in a controlled amount with said two or more colourless liquids to form a white ink-mixture wherein the viscosity is reduced by at least 5 mPa.s by reference to the white ink when measuring the viscosity at 40°C with a Brookfield DV-II+Pro at 12 rotations per minute and c) printing the white ink-mixture with the inkjet printer onto an ink-receiver, wherein at least two colourless liquids have a different surface tension.
A method of sample processing, comprising: providing a microfluidic device with at least one separation channel in fluid communication with a background electrolyte reservoir, a waste reservoir connected to the separation channel through a waste channel, and a sample reservoir connected to the separation channel through a sample channel that connects to the separation channel at a junction; injecting a fluid sample from the sample reservoir into the at least one separation channel by concurrently applying pressurized gas to the BGE reservoir and the sample reservoir, and a lower pressure to the waste reservoir; delivering fluid from the BGE reservoir into the at least one separation channel to define a plug (Sp) of the sample in the at least one separation channel downstream of the junction by reducing the gas pressure in the sample reservoir, so that the gas pressure in the BGE reservoir is greater than the gas pressure in the sample reservoir; electrophoretically separating an analyte component of the sample from other sample components in the at least one separation channel by generating an axial electric field within the separation channel; and performing at least one of: (a) electrospraying the separated analyte component from at least one emitter in fluid communication with the at least one separation channel; and (b) measuring an electrical signal corresponding to the separated analyte component in or emerging from the separation channel. providing a microfluidic device with at least one separation channel in fluid communication with a background electrolyte reservoir, a waste reservoir connected to the separation channel through a waste channel, and a sample reservoir connected to the separation channel through a sample channel that connects to the separation channel at a junction; injecting a fluid sample from the sample reservoir into the at least one separation channel by concurrently applying pressurized gas to the BGE reservoir and the sample reservoir, and a lower pressure to the waste reservoir; delivering fluid from the BGE reservoir into the at least one separation channel to define a plug (Sp) of the sample in the at least one separation channel downstream of the junction by reducing the gas pressure in the sample reservoir, so that the gas pressure in the BGE reservoir is greater than the gas pressure in the sample reservoir; electrophoretically separating an analyte component of the sample from other sample components in the at least one separation channel by generating an axial electric field within the separation channel; and performing at least one of: (a) electrospraying the separated analyte component from at least one emitter in fluid communication with the at least one separation channel; and (b) measuring an electrical signal corresponding to the separated analyte component in or emerging from the separation channel. (a) electrospraying the separated analyte component from at least one emitter in fluid communication with the at least one separation channel; and (b) measuring an electrical signal corresponding to the separated analyte component in or emerging from the separation channel.
A cutter holder structure, comprising: a cutter arbor, having a through hole therein, one end of the through hole being formed with an inner tapered hole, one end of the cutter arbor being provided with an external thread; a connecting shaft, having a tapered section at one end thereof, the tapered section corresponding to the inner tapered hole of the cutter arbor, one end of the tapered section being formed with a first inner screw hole for locking a set screw, another end of the connecting shaft being formed with a second inner screw hole, the connecting shaft further having a horizontal positioning hole that penetrates through the connecting shaft and is adjacent to the tapered section, two ends of the positioning hole being formed with cylindrical holes, a reduced hole being defined between the cylindrical holes at the two ends of the positioning hole, two ends of the reduced hole being connected to the cylindrical holes; a nut, having a third inner screw hole at one end and an axial hole at another end, the nut further having a horizontal countersink hole and a horizontal fourth inner screw hole, an eccentric distance (e) being defined between a center of the countersink hole and a center of the fourth inner screw hole; a screw, inserted through the countersink hole and locked into the fourth inner screw hole. a cutter arbor, having a through hole therein, one end of the through hole being formed with an inner tapered hole, one end of the cutter arbor being provided with an external thread; a connecting shaft, having a tapered section at one end thereof, the tapered section corresponding to the inner tapered hole of the cutter arbor, one end of the tapered section being formed with a first inner screw hole for locking a set screw, another end of the connecting shaft being formed with a second inner screw hole, the connecting shaft further having a horizontal positioning hole that penetrates through the connecting shaft and is adjacent to the tapered section, two ends of the positioning hole being formed with cylindrical holes, a reduced hole being defined between the cylindrical holes at the two ends of the positioning hole, two ends of the reduced hole being connected to the cylindrical holes; a nut, having a third inner screw hole at one end and an axial hole at another end, the nut further having a horizontal countersink hole and a horizontal fourth inner screw hole, an eccentric distance (e) being defined between a center of the countersink hole and a center of the fourth inner screw hole; a screw, inserted through the countersink hole and locked into the fourth inner screw hole.
A method of preparing a preserved multi-dose formulation, wherein the formulation is an immunogenic composition in the form of an oil-in-water emulsion, said method comprising or consisting essentially of the following steps: (a) providing at least two doses comprising an effective amount of at least one antigen; (b) providing between about 0.1 mg/mL and 5 mg/mL expressed as w/v of the formulation of a non-mercurial preservative which is an antimicrobial polyamide polymer having the following structure: wherein the weight average molecular weight (WAMW) is from about 1.0 kDa to about 15.0 kDa, as measured by size exclusion chromatography; (c) combining the antigen and the non-mercurial preservative with an aqueous and/or oily component to form a preserved multi-dose liquid oil-in-water formulation; (d) optionally providing one or more excipients; (e) optionally providing a container for containing the liquid formulation; (f) optionally sterilizing and transferring the liquid formulation to the container; and (g) optionally freeze-drying, lyophilizing and/or vitrifying the liquid formulation; thereby producing the preserved multi-dose formulation; and wherein the formulation contains no mercurial preservative. (a) providing at least two doses comprising an effective amount of at least one antigen; (b) providing between about 0.1 mg/mL and 5 mg/mL expressed as w/v of the formulation of a non-mercurial preservative which is an antimicrobial polyamide polymer having the following structure: wherein the weight average molecular weight (WAMW) is from about 1.0 kDa to about 15.0 kDa, as measured by size exclusion chromatography; (c) combining the antigen and the non-mercurial preservative with an aqueous and/or oily component to form a preserved multi-dose liquid oil-in-water formulation; (d) optionally providing one or more excipients; (e) optionally providing a container for containing the liquid formulation; (f) optionally sterilizing and transferring the liquid formulation to the container; and (g) optionally freeze-drying, lyophilizing and/or vitrifying the liquid formulation;
A method for manufacturing a composite body, the method comprising: a sintering step of molding and heating a blend containing a boron carbonitride powder and a sintering aid to obtain a boron nitride sintered body including boron nitride particles and pores; and an impregnating step of impregnating the boron nitride sintered body with a resin composition, the composite body having the boron nitride sintered body and a resin filled in at least some of the pores of the boron nitride sintered body. a sintering step of molding and heating a blend containing a boron carbonitride powder and a sintering aid to obtain a boron nitride sintered body including boron nitride particles and pores; and an impregnating step of impregnating the boron nitride sintered body with a resin composition, the composite body having the boron nitride sintered body and a resin filled in at least some of the pores of the boron nitride sintered body.
An abrasive article (200; 300; 400; 500) comprising: a flexible abrasive layer having opposed first and second major surfaces; a permeable backing bonded to the second major surface, the permeable backing being resiliently compressible; a plurality of slits (230; 330; 430; 530) disposed on the first major surface and penetrating through the flexible abrasive layer and at least partially through the permeable backing; and a structured member disposed between the flexible abrasive layer and the permeable backing, wherein the structured member and the flexible abrasive layer have respective three-dimensional patterns of discrete, isolated wells that conform with each other. a flexible abrasive layer having opposed first and second major surfaces; a permeable backing bonded to the second major surface, the permeable backing being resiliently compressible; a plurality of slits (230; 330; 430; 530) disposed on the first major surface and penetrating through the flexible abrasive layer and at least partially through the permeable backing; and a structured member disposed between the flexible abrasive layer and the permeable backing, wherein the structured member and the flexible abrasive layer have respective three-dimensional patterns of discrete, isolated wells that conform with each other.
An ultrasound diagnostic apparatus comprising: an ultrasound probe that is configured to be positioned at a measurement spot of a subject to perform transmission and reception of an ultrasonic wave to and from the subject; a head-mounted display that is configured to be mounted on a head of a user and has a camera unit configured to acquire a camera image obtained by imaging a field of view in front of the user and a display unit; a measurement spot decision unit that, in a case where subject information including at least one of a symptom or a disease of the subject is input, decides at least one measurement spot where the transmission and reception of the ultrasonic wave by the ultrasound probe is desired, based on the input subject information; and a navigation image generation unit that recognizes the subject from the camera image acquired by the camera unit of the head-mounted display, generates a navigation image indicating a position of the measurement spot decided by the measurement spot decision unit with respect to the recognized subject, and displays the generated navigation image on the display unit of the head-mounted display. an ultrasound probe that is configured to be positioned at a measurement spot of a subject to perform transmission and reception of an ultrasonic wave to and from the subject; a head-mounted display that is configured to be mounted on a head of a user and has a camera unit configured to acquire a camera image obtained by imaging a field of view in front of the user and a display unit; a measurement spot decision unit that, in a case where subject information including at least one of a symptom or a disease of the subject is input, decides at least one measurement spot where the transmission and reception of the ultrasonic wave by the ultrasound probe is desired, based on the input subject information; and a navigation image generation unit that recognizes the subject from the camera image acquired by the camera unit of the head-mounted display, generates a navigation image indicating a position of the measurement spot decided by the measurement spot decision unit with respect to the recognized subject, and displays the generated navigation image on the display unit of the head-mounted display.
A security sealing device comprising a sealing element, an integrated circuit and an antenna (2,4) connected to said integrated circuit, said integrated circuit and said antenna (2,4) forming a RFID circuit, characterized by the fact that the device comprises a housing containing said integrated circuit and a portion of the antenna (2,4) forming a partial antenna, that said sealing element is conductive and is connected to said partial antenna and forming a part of said antenna (2,4) and that at least a part of said sealing element extends outside of said housing.
An aerosol delivery system comprising a nebulizer, and a humidifier for a nebulizer gas flow to the nebulizer, wherein the system comprises a controller configured to vary humidity level of the nebulizer gas flow, characterized in that, the controller is configured to control humidity of the nebulizer gas flow to the nebuliser so that the nebulizer brings the relative humidity of the nebulizer output flow up to a target level, and the controller is configured to vary humidification according to nebulization rate or according to gas flow rate.
An optical particle sensor comprising: - at least one channel intended to accommodate a fluid transporting at least one particle, and to be crossed by light rays such that said light rays are partially scattered by the at least one particle, - a plurality of photosensors capable of receiving said scattered light rays, said detector being characterised in that it comprises at least one optical guide comprising at least one first portion and one second portion which are separated from each other by the channel, the first portion of the guide having a first inlet and a first outlet opening onto the channel and the second portion of the guide having a second inlet and a second outlet opening onto the channel, said first and second portions (41, 42) being arranged so that the first inlet is opposite to the second outlet, and the second inlet is opposite to the first outlet, the optical guide being configured to: - collect, at least one inlet of the guide from the first and second inlets (51, 52), light rays which are not scattered by the at least one particle and having crossed the channel, and to - reinject, via at least one outlet of the guide from the first and second outlets (61, 62), said unscattered light rays into the channel. - at least one channel intended to accommodate a fluid transporting at least one particle, and to be crossed by light rays such that said light rays are partially scattered by the at least one particle, - a plurality of photosensors capable of receiving said scattered light rays, - collect, at least one inlet of the guide from the first and second inlets (51, 52), light rays which are not scattered by the at least one particle and having crossed the channel, and to - reinject, via at least one outlet of the guide from the first and second outlets (61, 62), said unscattered light rays into the channel.
Arrangement comprising an electrical device, in particular a converter or an inverter, and a component, the electrical device comprising a cooling member, a base plate being fastened to the cooling member, and the component being connected to a first or second adapter plate (24, 90) fastened to the base plate, the base plate in particular being pressed onto the cooling member by the screw head of a screw that is screwed into a threaded bore in the cooling member, characterised in that the base plate acts as a shielding plate, the base plate being electrically connected to the cooling member, which is metallic, the base plate being used for retaining a power supply cable, the component being connected to the first or second adapter plate (24, 90) in a heat-conducting manner. the electrical device comprising a cooling member, a base plate being fastened to the cooling member, and the component being connected to a first or second adapter plate (24, 90) fastened to the base plate, the base plate in particular being pressed onto the cooling member by the screw head of a screw that is screwed into a threaded bore in the cooling member, characterised in that the base plate acts as a shielding plate, the base plate being electrically connected to the cooling member, which is metallic, the base plate being used for retaining a power supply cable, the component being connected to the first or second adapter plate (24, 90) in a heat-conducting manner.
A lighting module, comprising: a base panel; a plurality of low-power light-emitting diode chips attached directly to the base panel in electrical communication with a conductive trace (112, 114), wherein the plurality of light-emitting diode chips is attached directly to the base panel without underlying packaging; and a power source coupled to the conductive trace (112, 114); wherein the plurality of light-emitting diode chips have a rated current; characterized by the power source being adapted to deliver a drive current of less than about 75% of the rated current to increase an allowable pack-density without requiring auxiliary heat sinking techniques; and wherein at least a portion of the base panel has a lumens-density metric greater than 1.0 x 10 6 lm 2 /mm 2 W. a base panel; a plurality of low-power light-emitting diode chips attached directly to the base panel in electrical communication with a conductive trace (112, 114), wherein the plurality of light-emitting diode chips is attached directly to the base panel without underlying packaging; and a power source coupled to the conductive trace (112, 114); wherein the plurality of light-emitting diode chips have a rated current; characterized by the power source being adapted to deliver a drive current of less than about 75% of the rated current to increase an allowable pack-density without requiring auxiliary heat sinking techniques; and wherein at least a portion of the base panel has a lumens-density metric greater than 1.0 x 10 6 lm 2 /mm 2 W.