A touch substrate, including: a base substrate; a plurality of first touch electrodes disposed on the base substrate and arranged in a first direction; and a plurality of second touch electrodes disposed on the base substrate and arranged in a second direction, wherein the touch substrate includes a touch region and a peripheral region located at a periphery of the touch region, and the touch region includes a rounded-corner region, the plurality of first touch electrodes include at least one first rounded-corner touch electrode extending into the rounded-corner region, the touch substrate further includes a touch-driving connection line connected with each of the at least one first rounded-corner touch electrode, the plurality of second touch electrodes include at least one second rounded-corner touch electrode extending into the rounded-corner region, the touch substrate further includes a touch-sensing connection line connected with each of the at least one second rounded-corner touch electrode, characterized in that the touch-sensing connection line includes a first U-shaped bent portion and a first extension portion extending in the second direction, the first U-shaped bent portion includes a first bent portion, a second bent portion, and a first connection portion, the first bent portion is electrically connected with the second rounded-corner touch electrode and located at a side of the touch-driving connection line close to the touch region, the second bent portion is connected with the first extension portion and located at a side of the touch-driving connection line away from the touch region, and the first connection portion connects the first bent portion with the second bent portion, and the first connection portion and the touch-driving connection line are overlapped with each other in a direction perpendicular to the base substrate, and, in an overlap region of the first connection portion and the touch-driving connection line, the first connection portion and the touch-driving connection line are arranged in different layers. a base substrate; a plurality of first touch electrodes disposed on the base substrate and arranged in a first direction; and a plurality of second touch electrodes disposed on the base substrate and arranged in a second direction, wherein the touch substrate includes a touch region and a peripheral region located at a periphery of the touch region, and the touch region includes a rounded-corner region, the plurality of first touch electrodes include at least one first rounded-corner touch electrode extending into the rounded-corner region, the touch substrate further includes a touch-driving connection line connected with each of the at least one first rounded-corner touch electrode, the plurality of second touch electrodes include at least one second rounded-corner touch electrode extending into the rounded-corner region, the touch substrate further includes a touch-sensing connection line connected with each of the at least one second rounded-corner touch electrode, characterized in that the touch-sensing connection line includes a first U-shaped bent portion and a first extension portion extending in the second direction, the first U-shaped bent portion includes a first bent portion, a second bent portion, and a first connection portion, the first bent portion is electrically connected with the second rounded-corner touch electrode and located at a side of the touch-driving connection line close to the touch region, the second bent portion is connected with the first extension portion and located at a side of the touch-driving connection line away from the touch region, and the first connection portion connects the first bent portion with the second bent portion, and the first connection portion and the touch-driving connection line are overlapped with each other in a direction perpendicular to the base substrate, and, in an overlap region of the first connection portion and the touch-driving connection line, the first connection portion and the touch-driving connection line are arranged in different layers.