A multiple input and multiple output distributed antenna system, comprising: a head-end unit (315, 414, 503) communicatively coupled to a base station (322, 402, 501); and a remote unit (310, 404, 500, 600) communicatively coupled to the head-end unit (315, 414, 503) and located remotely from the head-end unit (315, 414, 503), wherein the remote unit (310, 404, 500, 600) comprises: a plurality of uplink signal paths (300a, 300b, 400a, 400b, 504a, 504b, 602a, 602b); a first plurality of mixers (304a, 304b, 406a, 406b, 507a, 507b, 605a, 605b) located in the plurality of uplink signal paths, the first plurality of mixers being coupled to first oscillators (305a, 305b, 407a, 407b, 508a, 508b, 606a, 606b) and configured to produce a plurality of uplink signals occupying non-overlapping frequency bands and representative of wireless signals; a first summer (308, 410, 511, 609) coupled to the plurality of uplink signal paths and configured to sum the plurality of uplink signals to form summed uplink signals; and a first shared wideband analog-to-digital converter (309, 411, 512, 611) configured to convert the summed uplink signals to digital uplink signals; wherein the head-end unit (315, 414, 503) is configured to provide uplink signals based on the digital uplink signals to one or more signal ports of the base station (322, 402, 501). a head-end unit (315, 414, 503) communicatively coupled to a base station (322, 402, 501); and a remote unit (310, 404, 500, 600) communicatively coupled to the head-end unit (315, 414, 503) and located remotely from the head-end unit (315, 414, 503), wherein the remote unit (310, 404, 500, 600) comprises: a plurality of uplink signal paths (300a, 300b, 400a, 400b, 504a, 504b, 602a, 602b); a first plurality of mixers (304a, 304b, 406a, 406b, 507a, 507b, 605a, 605b) located in the plurality of uplink signal paths, the first plurality of mixers being coupled to first oscillators (305a, 305b, 407a, 407b, 508a, 508b, 606a, 606b) and configured to produce a plurality of uplink signals occupying non-overlapping frequency bands and representative of wireless signals; a first summer (308, 410, 511, 609) coupled to the plurality of uplink signal paths and configured to sum the plurality of uplink signals to form summed uplink signals; and a first shared wideband analog-to-digital converter (309, 411, 512, 611) configured to convert the summed uplink signals to digital uplink signals; wherein the head-end unit (315, 414, 503) is configured to provide uplink signals based on the digital uplink signals to one or more signal ports of the base station (322, 402, 501). a plurality of uplink signal paths (300a, 300b, 400a, 400b, 504a, 504b, 602a, 602b); a first plurality of mixers (304a, 304b, 406a, 406b, 507a, 507b, 605a, 605b) located in the plurality of uplink signal paths, the first plurality of mixers being coupled to first oscillators (305a, 305b, 407a, 407b, 508a, 508b, 606a, 606b) and configured to produce a plurality of uplink signals occupying non-overlapping frequency bands and representative of wireless signals; a first summer (308, 410, 511, 609) coupled to the plurality of uplink signal paths and configured to sum the plurality of uplink signals to form summed uplink signals; and a first shared wideband analog-to-digital converter (309, 411, 512, 611) configured to convert the summed uplink signals to digital uplink signals; wherein the head-end unit (315, 414, 503) is configured to provide uplink signals based on the digital uplink signals to one or more signal ports of the base station (322, 402, 501).