A pyro-fuse control circuit, comprising: a current sensing circuit configured to determine whether the current flowing in a conductor exceeds a threshold current; and a diagnostic circuit coupled to the current sensing circuit, and configured to determine whether an indication of current exceeding the threshold current generated by the current sensing circuit is caused by current flowing in the conductor and is not caused by a fault in the current sensing circuit, characterized in that the current sensing circuit comprises a first isolation amplifier configured to measure a voltage across a shunt resistor disposed in the conductor; wherein the current sensing circuit comprises a first comparator coupled to an output of the first isolation amplifier, the first comparator configured to compare an output voltage of the first isolation amplifier to a threshold voltage representative of the threshold current; wherein the diagnostic circuit comprises: a switch coupled to a first input terminal of the first isolation amplifier; and a second isolation amplifier coupled to a second input terminal of the first isolation amplifier, the second isolation amplifier configured to detect current flow from the switch through the second input terminal of the first isolation amplifier; a second comparator coupled to an output of the second isolation amplifier, the comparator configured to compare an output voltage of the second isolation amplifier to a threshold voltage representative of a predetermined current flowing in the second input terminal of the first isolation amplifier; further comprising control circuitry configured to trigger a pyro-fuse based on the output of the first comparator indicating that current exceeds the threshold current and the output of the second comparator indicating that current flowing in the second terminal of the first isolation amplifier exceeds the predetermined current. a current sensing circuit configured to determine whether the current flowing in a conductor exceeds a threshold current; and a diagnostic circuit coupled to the current sensing circuit, and configured to determine whether an indication of current exceeding the threshold current generated by the current sensing circuit is caused by current flowing in the conductor and is not caused by a fault in the current sensing circuit, the current sensing circuit comprises a first isolation amplifier configured to measure a voltage across a shunt resistor disposed in the conductor; wherein the current sensing circuit comprises a first comparator coupled to an output of the first isolation amplifier, the first comparator configured to compare an output voltage of the first isolation amplifier to a threshold voltage representative of the threshold current; wherein the diagnostic circuit comprises: a switch coupled to a first input terminal of the first isolation amplifier; and a second isolation amplifier coupled to a second input terminal of the first isolation amplifier, the second isolation amplifier configured to detect current flow from the switch through the second input terminal of the first isolation amplifier; a second comparator coupled to an output of the second isolation amplifier, the comparator configured to compare an output voltage of the second isolation amplifier to a threshold voltage representative of a predetermined current flowing in the second input terminal of the first isolation amplifier; a switch coupled to a first input terminal of the first isolation amplifier; and a second isolation amplifier coupled to a second input terminal of the first isolation amplifier, the second isolation amplifier configured to detect current flow from the switch through the second input terminal of the first isolation amplifier; a second comparator coupled to an output of the second isolation amplifier, the comparator configured to compare an output voltage of the second isolation amplifier to a threshold voltage representative of a predetermined current flowing in the second input terminal of the first isolation amplifier; further comprising control circuitry configured to trigger a pyro-fuse based on the output of the first comparator indicating that current exceeds the threshold current and the output of the second comparator indicating that current flowing in the second terminal of the first isolation amplifier exceeds the predetermined current.