mhurhangee/ep-ind-claims huggingface dataset:
A health device for applying pressure to one or more areas of a user's skin, comprising: one or more actuator members, each comprising a smart shape-changing material of a class which is disposed to change shape in response to a change in temperature or to the application of an electrical stimulus; one or more stimulating means adapted to deliver electrical stimuli to the one or more actuator members, for stimulating shape change of the smart shape-changing material, the one or more stimulating means comprising electrodes (40,64), electrically coupled to the smart shape-changing material of each of the one or more actuator members; and a controller operatively coupled with, and adapted to control the one or more stimulating means to deliver electrical stimuli to the shape-changing material in order to stimulate the smart shape-changing materials of the one or more actuator members to deliver pressures to one or more pressure delivery areas of a user's skin, wherein the device comprises one or more skin stimulation elements, electrically connected with the controller, adapted to transfer electrical stimuli generated by the controller to one or more areas of a user's skin, wherein the electrical stimuli are for sensing an impedance of the skin, and wherein the controller is adapted to determine an impedance of the skin through measuring one or more electrical parameters of the delivered electrical stimuli. one or more actuator members, each comprising a smart shape-changing material of a class which is disposed to change shape in response to a change in temperature or to the application of an electrical stimulus; one or more stimulating means adapted to deliver electrical stimuli to the one or more actuator members, for stimulating shape change of the smart shape-changing material, the one or more stimulating means comprising electrodes (40,64), electrically coupled to the smart shape-changing material of each of the one or more actuator members; and a controller operatively coupled with, and adapted to control the one or more stimulating means to deliver electrical stimuli to the shape-changing material in order to stimulate the smart shape-changing materials of the one or more actuator members to deliver pressures to one or more pressure delivery areas of a user's skin, wherein the device comprises one or more skin stimulation elements, electrically connected with the controller, adapted to transfer electrical stimuli generated by the controller to one or more areas of a user's skin, wherein the electrical stimuli are for sensing an impedance of the skin, and wherein the controller is adapted to determine an impedance of the skin through measuring one or more electrical parameters of the delivered electrical stimuli.
A bispecific antibody comprising a first variable domain with a first antigen-binding site that binds EGFR and a second variable domain with a second antigen-binding site that binds ErbB-3, wherein said first variable domain comprises a heavy chain variable region with a CDR1, CDR2 and CDR3 region comprising an amino acid sequence of NNAIN (SEQ ID NO: 18), WINTITGDPTYAQGFTG (SEQ ID NO: 20), and EEFLEWLFFDY (SEQ ID NO: 22) respectively, or a heavy chain CDR1, CDR2 and CDR3 amino acid sequence that differs in at most three amino acids from the CDR1, CDR2 and CDR3 amino acid sequence NNAIN (SEQ ID NO: 18), WINTITGDPTYAQGFTG (SEQ ID NO: 20), and EEFLEWLFFDY (SEQ ID NO: 22) and said second variable domain comprises a heavy chain variable region with a CDR1, CDR2 and CDR3 region comprising an amino acid sequence of GYYMH (SEQ ID NO: 90), WINPNSGGTNYAQKFQG (SEQ ID NO: 91), and DHGSRHFWSYWGFDY (SEQ ID NO: 92) respectively or a heavy chain CDR1, CDR2 and CDR3 amino acid sequence that differs in at most three amino acids from the CDR1, CDR2 and CDR3 amino acid sequence GYYMH (SEQ ID NO: 90), WINPNSGGTNYAQKFQG(SEQ ID NO: 91), and DHGSRHFWSYWGFDY (SEQ ID NO: 92), and wherein said first and second variable domains comprise a common light chain comprising the amino acid sequence
Method for creating an environment model of a vehicle, wherein a lane (207, 208, 209, 210) is ascertained on the basis of objects (201, 202, 203) and/or free space boundaries and/or roadway boundaries (204, 205), wherein the lane (207, 208, 209, 210) indicates the zone around the vehicle in which the vehicle can drive freely, wherein the lane (207, 208, 209, 210) comprises at least one lane segment, wherein the lane segment comprises at least one lane segment boundary, in particular a front lane segment boundary, a rear lane segment boundary, a left-hand lane segment boundary and a right-hand lane segment boundary, wherein the distance from the vehicle to the lane segment boundary is determined, and wherein the lane is made available to a driver assistance system, characterized in that the speed of change in the distance from the vehicle to at least one lane segment boundary is determined.
A safety mechanism for ensuring disposable use of a staple cartridge in a stapler, comprising: the staple cartridge, a staple cartridge base, a sliding block, a cutter, and a staple anvil, wherein the staple cartridge base is centrally provided with a central track, a proximal end of the staple cartridge base is provided with a bias track, the bias track is in communication with a proximal end of the central track, a distal end of the bias track is provided with a blocking groove, and the sliding block is assembled at a proximal end of the staple cartridge; a first guide structure is provided on the cutter; characterised in that the sliding block is provided with a second guide structure corresponding to the first guide structure of the cutter, and the second guide structure is capable of guiding the first guide structure to a central position from a biased position, so that the cutter enters the central track.
A method for filtering distance information from a 3D-measurement camera system, the method comprising: comparing amplitude or distance information for pixels to respective amplitude or distance information of adjacent pixels; and averaging distance information for the pixels with the distance information of the adjacent pixels when amplitude or distance information for the pixels is within a range of the amplitudes or distances for the adjacent pixels. comparing amplitude or distance information for pixels to respective amplitude or distance information of adjacent pixels; and averaging distance information for the pixels with the distance information of the adjacent pixels when amplitude or distance information for the pixels is within a range of the amplitudes or distances for the adjacent pixels.
A set-up device for a tool for stamping or shaping planar materials, the device comprising at least one punch and one die, - with a punch holder in which the punch can be inserted, - with a die holder in which the die or a die plate holding the die can be inserted, - with at least one guide for moving the punch holder and the die holder toward one another, characterized in that, - the punch holder can be transferred along the guide to a measurement position in which the punch sits on a surface of an object to be measured and the bottom side of the object to be measured sits on the die, - a measuring device detects a distance of the punch holder to a zero point of the die holder and a distance of the object to be measured to the zero point of the die holder, and - an evaluation device evaluates the distances detected by the measuring device and outputs at least one punch length of the punch and a die height of the die or a die height of the die arranged in the die plate. - with a punch holder in which the punch can be inserted, - with a die holder in which the die or a die plate holding the die can be inserted, - with at least one guide for moving the punch holder and the die holder toward one another, characterized in that, - the punch holder can be transferred along the guide to a measurement position in which the punch sits on a surface of an object to be measured and the bottom side of the object to be measured sits on the die, - a measuring device detects a distance of the punch holder to a zero point of the die holder and a distance of the object to be measured to the zero point of the die holder, and - an evaluation device evaluates the distances detected by the measuring device and outputs at least one punch length of the punch and a die height of the die or a die height of the die arranged in the die plate.
Force sensor comprising: - a first part comprising a detection coil; - a second part positioned opposite the first part and comprising: ∘ a ferromagnetic plate that is translationally movable relative to the first part so as to move towards said part when a force is transferred to the sensor and to reduce the reluctance of a magnetic circuit formed by said two parts (PA1, PA2) in series with a variable gap; ∘ an electronic detection circuit configured to generate a signal dependent on the reluctance of the magnetic circuit, characterised in that the ferromagnetic plate is formed by an amorphous metal alloy. - a first part comprising a detection coil; - a second part positioned opposite the first part and comprising: ∘ a ferromagnetic plate that is translationally movable relative to the first part so as to move towards said part when a force is transferred to the sensor and to reduce the reluctance of a magnetic circuit formed by said two parts (PA1, PA2) in series with a variable gap; ∘ an electronic detection circuit configured to generate a signal dependent on the reluctance of the magnetic circuit, characterised in that the ferromagnetic plate is formed by an amorphous metal alloy. ∘ a ferromagnetic plate that is translationally movable relative to the first part so as to move towards said part when a force is transferred to the sensor and to reduce the reluctance of a magnetic circuit formed by said two parts (PA1, PA2) in series with a variable gap; ∘ an electronic detection circuit configured to generate a signal dependent on the reluctance of the magnetic circuit,
A mouthpiece for an apparatus to aid aerosol delivery to a patient, the mouthpiece comprising: a body; a bore extending through the body; an upper step on a top side of the mouthpiece; and a lower step on a bottom side of the mouthpiece; wherein each of the upper step and the lower step comprises a surface configured to engage at least a portion of teeth or a tooth of a user of the apparatus; characterised in that the mouthpiece further comprises a movable member, the body has thereon either the upper step or the lower step, and the movable member has the other of the upper step or the lower step so that a distance between the upper step and the lower step is adjustable; wherein movement of the moveable member adjusts or imparts a selected amount of mandibular displacement to the patient. a body; a bore extending through the body; an upper step on a top side of the mouthpiece; and a lower step on a bottom side of the mouthpiece; characterised in that the mouthpiece further comprises a movable member, the body has thereon either the upper step or the lower step, and the movable member has the other of the upper step or the lower step so that a distance between the upper step and the lower step is adjustable; wherein movement of the moveable member adjusts or imparts a selected amount of mandibular displacement to the patient.
A process for extracting a perfluoropolyether from a lubricating grease, comprising: (a) contacting a solvent comprising a liquid or supercritical carbon dioxide with the lubricating grease comprising a thickener and the perfluoropolyether in an extraction zone to form an extraction solution comprising an extracted perfluoropolyether; and (b) recovering the extracted perfluoropolyether from the extraction solution by evaporating the liquid or super critical carbon dioxide; wherein the recovered extracted perfluoropolyether comprises no more than about 2 wt % of the thickener. (a) contacting a solvent comprising a liquid or supercritical carbon dioxide with the lubricating grease comprising a thickener and the perfluoropolyether in an extraction zone to form an extraction solution comprising an extracted perfluoropolyether; and (b) recovering the extracted perfluoropolyether from the extraction solution by evaporating the liquid or super critical carbon dioxide; wherein the recovered extracted perfluoropolyether comprises no more than about 2 wt % of the thickener.
Compound of formula wherein R' signifies hydrogen, unbranched C 1 -C 6 -alkyl or branched C 3 -C 6 -alkyl, or SO 3 Y, or SO 2 CH 2 CH 2 OH, R 2 signifies hydrogen, unbranched C 1 -C 6 -alkyl or branched C 3 -C 6 -alkyl, or SO 3 Y, or SO 2 CH 2 CH 2 OH, or -NHCH 2 CH 2 OH, R 3 and R 4 signify independently from each other hydrogen, unbranched C 1 -C 6 -alkyl or branched C 3 -C 6 -alkyl, unbranched C 1 -C 6 -alkoxy or branched C 3 -C 6 -alkoxy, R 5 signifies hydrogen or SO 3 Y, R 6 signifies hydrogen or SO 3 Y, R 7 signifies hydrogen, unbranched C 1 -C 6 -alkyl or branched C 3 -C 6 -alkyl, phenyl, or unbranched C 1 -C 12 -alkoxy, or branched C 3 -C 12 -alkoxy, or NH 2, R 8 and R 9 signify independently from each other unbranched C 1 -C 6 -alkyl or branched C 3 -C 6 -alkyl, or aryl, or -(CH 2) n -aryl with n = 1, 2, 3 or 4; wherein Y signifies H + or an alkali metal cation, preferably Na + or K +; and wherein said compound of formula contains at least one SO 3 Y group. R' signifies hydrogen, unbranched C 1 -C 6 -alkyl or branched C 3 -C 6 -alkyl, or SO 3 Y, or SO 2 CH 2 CH 2 OH, R 2 signifies hydrogen, unbranched C 1 -C 6 -alkyl or branched C 3 -C 6 -alkyl, or SO 3 Y, or SO 2 CH 2 CH 2 OH, or -NHCH 2 CH 2 OH, R 3 and R 4 signify independently from each other hydrogen, unbranched C 1 -C 6 -alkyl or branched C 3 -C 6 -alkyl, unbranched C 1 -C 6 -alkoxy or branched C 3 -C 6 -alkoxy, R 5 signifies hydrogen or SO 3 Y, R 6 signifies hydrogen or SO 3 Y, R 7 signifies hydrogen, unbranched C 1 -C 6 -alkyl or branched C 3 -C 6 -alkyl, phenyl, or unbranched C 1 -C 12 -alkoxy, or branched C 3 -C 12 -alkoxy, or NH 2, R 8 and R 9 signify independently from each other unbranched C 1 -C 6 -alkyl or branched C 3 -C 6 -alkyl, or aryl, or -(CH 2) n -aryl with n = 1, 2, 3 or 4; wherein Y signifies H + or an alkali metal cation, preferably Na + or K +; and wherein said compound of formula contains at least one SO 3 Y group.
A mechanical tool, for the manipulation of smaller-sized objects such as dental implants, post-traumatic prostheses, screw, bolts, said mechanical tool comprising a first elongated shaft that is interiorly hollow having on its free end a defined geometric termination which can be coupled in a region of the object to be handled, and a second elongated shaft that passes through the middle of the first elongated shaft and has on its free end a defined geometric termination that projects outwardly from the first elongated shaft and can be coupled in a second region of the object to be handled, one of the two elongated shafts being able to rotate on its own central longitudinal axis in relation to the other elongated shaft, including an actuating means for carrying out said rotary action, characterised by the fact that the actuating means have a push button comprising a shaft that can be axially moved and it is coupled with the rotary shaft by means of a cam system.
Apparatus designed to determine and/or monitor the temperature of a medium, said apparatus comprising at least a temperature sensor arranged in a sensor head, wherein at least an internal volume of the sensor head is at least partially filled with at least a first material and at least partially filled with at least a second material, wherein the first material serves to fix at least one component (8, 9a, 9b) of the temperature sensor inside the sensor head and is designed to mechanically stabilize at least a component (8, 9a, 9b) of the temperature sensor inside the sensor head, and to protect against vibrations, wherein the at least one first material is a ceramic, particularly a magnesium oxide or an aluminum oxide, or a ceramic potting, particularly a hardened ceramic potting, and wherein the second material serves to conduct heat inside the sensor head, characterized in that the at least second material, present for example in powder form, is a carbon nanotube.
A vehicle transmission, comprising; a multi-ratio gearbox having a gearbox input shaft and a gearbox output shaft, the gearbox being operable to provide a driving connection between the gearbox input shaft and the gearbox output shaft at a selected one of a plurality of gear ratios, a torque converter having a torque converter input for connection to an engine, and a torque converter output driveably connected to the torque converter input by fluid coupling within the torque converter, a first driving connection between the torque converter output and the gearbox input shaft, a second driving connection between the torque converter input and the gearbox input shaft, and a selection means to select one of the first driving connection and the second driving connection, wherein the second driving connection comprises a connection to a casing of the torque converter, and the second driving connection comprises a first gear carried on a shaft connected to the casing of the torque converter and the first driving connection comprises a torque converter output shaft drivingly connected to the torque converter output, and the second driving connection comprises a lay shaft disposed alongside the torque converter output shaft wherein a second gear and third gear are mounted on the lay shaft, characterised in that the second gear is in mesh with the first gear, and wherein a fourth gear is provided on the torque converter output shaft in mesh with the third gear and the selection means comprises a clutch mounted on the lay shaft to drivingly connect one of the second gear and third gear to the lay shaft.
A medical device comprising: an elongate body including a distal portion and a proximal portion; a shaft within the elongate body, the shaft including a distal portion; an inflatable treatment element at the distal portion of the elongate body, at least a portion of the inflatable treatment element being coupled to the distal portion of the shaft, the inflatable treatment element defining an inner chamber; and at least one fiber sensor, at least a portion of each of the at least one fiber sensor being located within the inner chamber of the inflatable treatment element and including at least one singlemode waveguide segment and at least one multimode waveguide segment, each of the at least one fiber sensor including a proximal portion (96A, 96B) and a distal portion (94A, 94B), the distal portion being coupled to the distal portion of the shaft and the proximal portion being freely movable within the inner chamber of the inflatable treatment element. an elongate body including a distal portion and a proximal portion; a shaft within the elongate body, the shaft including a distal portion; an inflatable treatment element at the distal portion of the elongate body, at least a portion of the inflatable treatment element being coupled to the distal portion of the shaft, the inflatable treatment element defining an inner chamber; and at least one fiber sensor, at least a portion of each of the at least one fiber sensor being located within the inner chamber of the inflatable treatment element and including at least one singlemode waveguide segment and at least one multimode waveguide segment, each of the at least one fiber sensor including a proximal portion (96A, 96B) and a distal portion (94A, 94B), the distal portion being coupled to the distal portion of the shaft and the proximal portion being freely movable within the inner chamber of the inflatable treatment element.
A microfluidic device comprising arrays for detecting a plurality of targets in a sample, each array comprising: a plurality of capture agents or components thereof attached to a substrate in a plurality of substantially parallel lines forming a barcoded pattern, wherein the plurality of capture agents is disposed such that each capture agent is disposed along one line, wherein some or all of the substantially parallel lines are connected to one another through at least one of the ends, wherein each capture agent of the plurality of capture agents is bindingly distinguishable and positionally distinguishable from another and capable of specifically binding a target of the plurality of targets to form a plurality of capture agent target binding complexes, and wherein the capture agent target binding complexes are detectable along a plurality of substantially parallel lines forming a barcoded pattern, which can be detected with a single line scan perpendicular to the stripe direction, wherein said substantially parallel lines are formed by microfluidic channels or portions thereof that are connected to each other to form single channels configured in a serpentine-like shape such that the substantially parallel lines are connected to each other and are configured in a serpentine-like shape forming repeated barcode arrays. a plurality of capture agents or components thereof attached to a substrate in a plurality of substantially parallel lines forming a barcoded pattern, wherein the plurality of capture agents is disposed such that each capture agent is disposed along one line, wherein some or all of the substantially parallel lines are connected to one another through at least one of the ends, wherein each capture agent of the plurality of capture agents is bindingly distinguishable and positionally distinguishable from another and capable of specifically binding a target of the plurality of targets to form a plurality of capture agent target binding complexes, and wherein the capture agent target binding complexes are detectable along a plurality of substantially parallel lines forming a barcoded pattern, which can be detected with a single line scan perpendicular to the stripe direction, wherein said substantially parallel lines are formed by microfluidic channels or portions thereof that are connected to each other to form single channels configured in a serpentine-like shape such that the substantially parallel lines are connected to each other and are configured in a serpentine-like shape forming repeated barcode arrays.