mhurhangee/ep-ind-claims huggingface dataset:
A health and security management apparatus (3,300) for facilitating the management of health and security of a patient and their home, the management apparatus comprising a processing device having a processor, memory, a remote communications interface (4, 5, 50, 340, 51, 55) for communicating with a remote monitoring system which is arranged for communications with a plurality of the health and security apparatus, a local communications interface (50, 340, 53, 49, 72, 75) for communication with devices locally, a patient interface for operation by the patient, the patient interface comprising a display screen for display and input means for patient input, a health monitoring arrangement being arranged to obtain health data on patient health, and arranged to transmit the data via the remote communication interface to the remote monitoring system, a security monitoring arrangement arranged to obtain data on patient security, including personal alarm data and home security data, including obtaining the patient security data via the local communications interface from security devices (301, 311, 312, 303) locally, and arranged to transmit the data via the remote communications interface to the remote monitoring system, a home automation arrangement (30, 314) arranged to produce home automation data to control home automation devices (31, 32) in the patient's home, the home automation data being transmitted to the home automation devices via the local communication interface, and the home automation arrangement being arranged to receive home automation data from the remote monitoring system via the remote communications interface, for control of home automation devices from the remote monitoring system, wherein the remote communication interface comprises a plurality of different communication modules (4, 5, 50, 55, 72, 340), enabling communications by different pathways, to enable redundancy of communications with the remote monitoring system, and wherein the health and security management apparatus converges the health monitoring arrangement, the security monitoring arrangement and the home automation arrangement into a single apparatus, wherein the single apparatus comprises a plurality of units arranged to be mounted to each other, and wherein the health and security management apparatus being arranged to port all health data, security data and home automation data.
Ironing appliance comprising a water tank, a steam generator connected to the water tank by a supply circuit and a water treatment device comprising a cathode and an anode to precipitate the calcium carbonate, characterised in that the cathode and the anode are arranged in a container, independent from the tank, placed in the supply circuit connecting the tank to the steam generator, said supply circuit drawing water from the tank through an opening located closer to the anode than the cathode, and in that the water flow rate at the opening is less than 70 g/min.
An engine starting system for a twin engine installation comprising: a first engine arrangement comprising a first electric machine; a second engine arrangement comprising a second electric machine; characterised by an energy storage unit coupled to the first engine arrangement and the second engine arrangement and having at least a first super-capacitor and a second super-capacitor; and a DC to DC converter configured to receive a first voltage level from a power source, increase the first voltage level to a second voltage level, and charge the first super-capacitor and the second super-capacitor to the second voltage level. a first engine arrangement comprising a first electric machine; a second engine arrangement comprising a second electric machine; characterised by an energy storage unit coupled to the first engine arrangement and the second engine arrangement and having at least a first super-capacitor and a second super-capacitor; and a DC to DC converter configured to receive a first voltage level from a power source, increase the first voltage level to a second voltage level, and charge the first super-capacitor and the second super-capacitor to the second voltage level.
An LED having a radiation-emitting active layer, an n-type contact, a p-type contact and a current spreading layer wherein - the current spreading layer is arranged between the active layer and the n-type contact, - the current spreading layer has a multiply repeating layer sequence, - the layer sequence has at least one n-doped layer, an undoped layer and a layer composed of Al x Ga 1-x N, where 0 < x < 1, and - the layer composed of Al x Ga 1-x N has a concentration gradient of the Al content, characterized in that - the layer composed of Al x Ga 1-x N is arranged between the undoped layer and the n-doped layer. - the current spreading layer is arranged between the active layer and the n-type contact, - the current spreading layer has a multiply repeating layer sequence, - the layer sequence has at least one n-doped layer, an undoped layer and a layer composed of Al x Ga 1-x N, where 0 < x < 1, and - the layer composed of Al x Ga 1-x N has a concentration gradient of the Al content, - the layer composed of Al x Ga 1-x N is arranged between the undoped layer and the n-doped layer.
Nanodiamonds having a positive ζ-potential of at least 1 mV for use in a method of treatment of a disease, caused by aberrant FGF-FGFR signalling and/or aberrant FGF-FGFR interaction, through sequestration of one or more FGF family members wherein the disease caused by the aberrant FGF-FGFR signalling and/or aberrant FGF-FGFR interaction is selected from breast cancer, multiple myeloma, renal cell carcinoma, metastatic renal cell carcinoma, urothelial carcinoma, bladder cancer, endometrial cancer, lung metastasis, lymph node metastasis, melanoma, biliary cancer, gastric cancer, gastro-oesophageal cancer, glioma, glioblastoma, squamous cell carcinoma, cholangiocarcinoma, craniosynostoses, skeletal dysplasias, dwarfism and impaired bone growth or regeneration.
A method for wireless communication, comprising: defining a timeslot for slotted communication; and transmitting in the timeslot data and at least two instances of a control indication (306; 308), wherein each instance of the control indication is independently encoded and transmitted; wherein the control indication comprises a resource utilization message; and wherein the resource utilization message indicates a degree to which data reception is being adversely affected by interfering transmissions from at least one wireless node. defining a timeslot for slotted communication; and transmitting in the timeslot data and at least two instances of a control indication (306; 308), wherein each instance of the control indication is independently encoded and transmitted; wherein the control indication comprises a resource utilization message; and wherein the resource utilization message indicates a degree to which data reception is being adversely affected by interfering transmissions from at least one wireless node.
A method for producing 3,7-dimethyl-7-octenol of Formula: comprising steps of: subjecting a 3-methyl-butenyl nucleophilic reagent of General Formula: wherein M denotes Li, MgZ 1, ZnZ 1, Cu, CuZ 1, or CuLiZ 1, wherein Z 1 denotes a halogen atom or a 3-methyl-3-butenyl group, and a 1,3-dihalo-2-methylpropane compound of General Formula: wherein X 1 and X 2 are the same as or different from each other, and each of X 1 and X 2 denotes a halogen atom, to a coupling reaction to obtain a 2,6-dimethyl-6-heptenyl halide compound of General Formula: wherein Y is X 1 or X 2 as defined above; converting the 2,6-dimethyl-6-heptenyl halide compound into a 2,6-dimethyl-6-heptenyl nucleophilic reagent of General Formula: wherein E denotes Li or MgZ 2, wherein Z 2 is a halogen atom; and subjecting the 2,6-dimethyl-6-heptenyl nucleophilic reagent to an addition reaction with at least one electrophilic reagent selected from the group consisting of formaldehyde, paraformaldehyde and 1,3,5-trioxane, followed by a hydrolysis reaction to obtain the 3,7-dimethyl-7-octenol of Formula. subjecting a 3-methyl-butenyl nucleophilic reagent of General Formula: wherein M denotes Li, MgZ 1, ZnZ 1, Cu, CuZ 1, or CuLiZ 1, wherein Z 1 denotes a halogen atom or a 3-methyl-3-butenyl group, and a 1,3-dihalo-2-methylpropane compound of General Formula: wherein X 1 and X 2 are the same as or different from each other, and each of X 1 and X 2 denotes a halogen atom, to a coupling reaction to obtain a 2,6-dimethyl-6-heptenyl halide compound of General Formula: wherein Y is X 1 or X 2 as defined above; converting the 2,6-dimethyl-6-heptenyl halide compound into a 2,6-dimethyl-6-heptenyl nucleophilic reagent of General Formula: wherein E denotes Li or MgZ 2, wherein Z 2 is a halogen atom; and subjecting the 2,6-dimethyl-6-heptenyl nucleophilic reagent to an addition reaction with at least one electrophilic reagent selected from the group consisting of formaldehyde, paraformaldehyde and 1,3,5-trioxane, followed by a hydrolysis reaction to obtain the 3,7-dimethyl-7-octenol of Formula.
A pharmaceutical formulation comprising: a therapeutically effective amount of a bispecific protein comprising a soluble T cell receptor and an scFV; a surfactant; a bulking agent; and a stabiliser, wherein the w/w ratio of surfactant to protein is in the range of 0.75:1 to 1.5:1, the ratio of stabiliser to bulking agent is greater than 1:1, the surfactant is polysorbate 20, the bulking agent is mannitol, the stabiliser is sucrose and/or trehalose, and the bispecific protein is present at a concentration of less than 1 mg/ml. a therapeutically effective amount of a bispecific protein comprising a soluble T cell receptor and an scFV; a surfactant; a bulking agent; and a stabiliser,
A method for producing a panel of cells expressing mutant variants of a protein of interest, wherein one of said mutant variants of said protein of interest is expressed per cell from a single gene copy, said method comprising: a) inducing a double-strand break or a single-strand nick in the genome of cells at or in close proximity to a target site for mutagenesis in the gene encoding for said protein of interest, wherein said gene encoding for said protein of interest is comprised in the genome of the cells in a single copy, and wherein said single copy of the gene encoding for said protein of interest comprises an inactivating mutation at or in close proximity to said target site for mutagenesis; b) providing to the cells of step a) a library of different donor nucleic acid templates for the repair of the induced DSB or single-strand nick via homologous recombination, wherein the different donor nucleic acid templates of said library comprise different mutations at the position corresponding to said target site for mutagenesis and remove said inactivating mutation by homology-directed repair; c) selecting and/or enriching cells in which the inactivating mutation has been removed; and d) providing a panel of cells selected in step c), which is a panel of cells expressing different mutant variants of said protein of interest, wherein one of said different mutant variants of said protein of interest is expressed per cell from a single gene copy. a) inducing a double-strand break or a single-strand nick in the genome of cells at or in close proximity to a target site for mutagenesis in the gene encoding for said protein of interest, wherein said gene encoding for said protein of interest is comprised in the genome of the cells in a single copy, and wherein said single copy of the gene encoding for said protein of interest comprises an inactivating mutation at or in close proximity to said target site for mutagenesis; b) providing to the cells of step a) a library of different donor nucleic acid templates for the repair of the induced DSB or single-strand nick via homologous recombination, wherein the different donor nucleic acid templates of said library comprise different mutations at the position corresponding to said target site for mutagenesis and remove said inactivating mutation by homology-directed repair; c) selecting and/or enriching cells in which the inactivating mutation has been removed; and d) providing a panel of cells selected in step c), which is a panel of cells expressing different mutant variants of said protein of interest, wherein one of said different mutant variants of said protein of interest is expressed per cell from a single gene copy.
A compressor system for a vehicle with a drive unit, the compressor system comprising: a variable air compressor with a compressor shaft to be driven by the drive unit, the variable air compressor is configured to compress a variable volume of air within a time period; a control unit configured to control the variable air compressor to change the variable volume of air; an auxiliary device; and a controllable clutch configured to decouple the compressor shaft from the auxiliary device, characterized in that the compressor shaft extends through the variable air compressor to couple to the controllable clutch to drive the auxiliary device by the compressor shaft, the controllable clutch being installed between the variable air compressor and the auxiliary device and being capable of detaching the auxiliary device from a driveline. a variable air compressor with a compressor shaft to be driven by the drive unit, the variable air compressor is configured to compress a variable volume of air within a time period; a control unit configured to control the variable air compressor to change the variable volume of air; an auxiliary device; and a controllable clutch configured to decouple the compressor shaft from the auxiliary device, characterized in that the compressor shaft extends through the variable air compressor to couple to the controllable clutch to drive the auxiliary device by the compressor shaft, the controllable clutch being installed between the variable air compressor and the auxiliary device and being capable of detaching the auxiliary device from a driveline.
Assembly for a sampling pipette including a control rod at the end of which is arranged a control button for controlling the movement of the control rod along a longitudinal axis thereof, the button having a pressure surface for receiving the thumb of an operator, characterised in that the pressure surface of the control button is movable such as to be able, during operation, to assume multiple angles relative to the longitudinal axis of the control rod.
Rolling tool, with a base body for fastening the rolling tool in a rolling machine, and a profile part for shaping a workpiece to be rolled, wherein the base body and the profile part are constructed in several pieces and are connectable to one another and separable from one another in a non-destructive manner, characterised in that the base body and the profile part, in their interconnected position, are mounted movably relative to one another in a plane perpendicular to the rolling direction while exclusively overcoming static friction between them are mounted so as to be movable relative to one another. a base body for fastening the rolling tool in a rolling machine, and a profile part for shaping a workpiece to be rolled, wherein the base body and the profile part are constructed in several pieces and are connectable to one another and separable from one another in a non-destructive manner, characterised in that the base body and the profile part, in their interconnected position, are mounted movably relative to one another in a plane perpendicular to the rolling direction while exclusively overcoming static friction between them are mounted so as to be movable relative to one another.
An aqueous composition formulated for nasal administration comprising a pharmaceutically acceptable acetate or methanesulfonate salt of compound I or a racemate or enantiomer thereof, wherein compound I, or the racemate or enantiomer thereof, is dissolved in the aqueous composition at a concentration of between 150 mg/mL and 600 mg/mL.
A method for automatically managing a recorded interaction between a customer and an agent of a contact center, the method comprising: extracting, by a processor, features from the recorded interaction; computing, by the processor, an agent performance evaluation score of the recorded interaction by supplying the features to a prediction model, wherein the prediction model is trained by: extracting, by the processor, a plurality of historical interaction features from a plurality of historical interactions; receiving, by the processor, a plurality of manual evaluations, each of the manual evaluations corresponding to one of the plurality of historical interactions, and each of the manual evaluations comprising a score; and training, by the processor, the prediction model in accordance with a relationship between the historical interaction features of the historical interactions and the scores of corresponding ones of the manual evaluations; detecting, by the processor, a condition based on the agent performance evaluation score; matching, by the processor, the condition with an action; and controlling, by the processor, a workforce management server to assign a training session to the agent of the contact center in accordance with the agent performance evaluation score of the recorded interaction. extracting, by a processor, features from the recorded interaction; computing, by the processor, an agent performance evaluation score of the recorded interaction by supplying the features to a prediction model, wherein the prediction model is trained by: extracting, by the processor, a plurality of historical interaction features from a plurality of historical interactions; receiving, by the processor, a plurality of manual evaluations, each of the manual evaluations corresponding to one of the plurality of historical interactions, and each of the manual evaluations comprising a score; and training, by the processor, the prediction model in accordance with a relationship between the historical interaction features of the historical interactions and the scores of corresponding ones of the manual evaluations; extracting, by the processor, a plurality of historical interaction features from a plurality of historical interactions; receiving, by the processor, a plurality of manual evaluations, each of the manual evaluations corresponding to one of the plurality of historical interactions, and each of the manual evaluations comprising a score; and training, by the processor, the prediction model in accordance with a relationship between the historical interaction features of the historical interactions and the scores of corresponding ones of the manual evaluations; detecting, by the processor, a condition based on the agent performance evaluation score; matching, by the processor, the condition with an action; and controlling, by the processor, a workforce management server to assign a training session to the agent of the contact center in accordance with the agent performance evaluation score of the recorded interaction.
An arrangement for interconnecting electrochemical cells of the type having a membrane electrode assembly interposed between an anode gas diffusion layer and a cathode gas diffusion layer, and first and second current collectors coupled to said anode and cathode gas diffusion layers, respectively, wherein the first current collector extends from the anode side of one cell to the cathode side of an adjacent cell, and wherein the cell components are clamped together; the first current collector which is in contact with the anode gas diffusion layer (GDL; 208a) of a first electrochemical cell is configured to be connected to the cathode side of a second, adjacent electrochemical cell via an inert and electrically conductive member (204b; 504; 904; 1110); and wherein there is provided an insulating element (201; 319; 420; 520; 801) interposed between the anode current collector of the first cell and the cathode side of the second, adjacent cell, wherein electrical connection is provided by said inert conductive member; characterized in that the insulating element comprises an insulating spacer member (201a; 319; 420; 520; 801; 920; 1150) having a top and a bottom surface, and provided such that the bottom surface of the spacer member is in contact with a portion of the membrane electrode assembly of said second cell, and wherein said first current collector has an extended portion which is in contact with the upper surface of said spacer member (201a; 319; 420; 520; 801) when clamped.
A coated cutting tool comprising a substrate and a coating layer formed on a surface of the substrate, the coating layer including at least one α-type aluminum oxide layer, wherein, in the α-type aluminum oxide layer, a texture coefficient TC (1,2,11) of a (1,2,11) plane represented by the formula below is 1.4 or more and 6.9 or less: TC 1,2 11 = I 1,2 11 I 0 1,2 11 1 8 ∑ I h k l I 0 h k l − 1, wherein, I (h,k,l) denotes a peak intensity for an (h,k,l) plane in X-ray diffraction of the α-type aluminum oxide layer, I 0 (h,k,l) denotes a standard diffraction intensity for an (h,k,l) plane which is indicated on a JCPDS Card No. 10-0173 for α-type aluminum oxide, and (h,k,l) refers to eight crystal planes of (0,1,2), (1,0,4), (1,1,0), (1,1,3), (0,2,4), (1,1,6), (2,1,4) and (1,2,11), wherein an average thickness of the α-type aluminum oxide layer is from 1.0 μm or more to 15.0 μm or less, wherein the coating layer comprises a TiCN layer between the substrate and the α-type aluminum oxide layer, and a ratio I 311 /I 220 of a peak intensity I 311 for a (3,1,1) plane in X-ray diffraction of the TiCN layer to a peak intensity I 220 for a (2,2,0) plane in X-ray diffraction of the TiCN layer is from 1.5 or more to 20.0 or less, wherein the coating layer comprises, between the TiCN layer and the α-type aluminum oxide layer, an intermediate layer comprised of a compound of at least one kind selected from the group consisting of a Ti carbonate, a Ti oxynitride and a Ti carboxynitride, and wherein an average thickness of the coating layer is from 3.0 μm or more to 30.0 μm or less. wherein, I (h,k,l) denotes a peak intensity for an (h,k,l) plane in X-ray diffraction of the α-type aluminum oxide layer, I 0 (h,k,l) denotes a standard diffraction intensity for an (h,k,l) plane which is indicated on a JCPDS Card No. 10-0173 for α-type aluminum oxide, and (h,k,l) refers to eight crystal planes of (0,1,2), (1,0,4), (1,1,0), (1,1,3), (0,2,4), (1,1,6), (2,1,4) and (1,2,11), wherein an average thickness of the α-type aluminum oxide layer is from 1.0 μm or more to 15.0 μm or less, wherein the coating layer comprises a TiCN layer between the substrate and the α-type aluminum oxide layer, and a ratio I 311 /I 220 of a peak intensity I 311 for a (3,1,1) plane in X-ray diffraction of the TiCN layer to a peak intensity I 220 for a (2,2,0) plane in X-ray diffraction of the TiCN layer is from 1.5 or more to 20.0 or less, wherein the coating layer comprises, between the TiCN layer and the α-type aluminum oxide layer, an intermediate layer comprised of a compound of at least one kind selected from the group consisting of a Ti carbonate, a Ti oxynitride and a Ti carboxynitride, and wherein an average thickness of the coating layer is from 3.0 μm or more to 30.0 μm or less.