Device for the dimensional determination and the clinical evaluation of allergic wheals caused by a prick test, comprising the following components: (a) System for the acquisition of image of said wheals, said system comprising a video camera; (b) A test strip for the positioning of the allergens on a part of a patient's body, preferably the forearm; (c) A multimedia system comprising a software having the following functions: - optimization of the acquired images - identification of the wheals - interactive measuring of the form and dimensions of the identified wheals wherein said test strip comprises: cut-outs used for (i) administered allergens, (ii) reference allergens, characterised in that the test strip further comprises: targeting spots and a reference-color scale, said targeting spots and reference-color scale being provided for allowing to calibrate respectively the focusing and the color of the video camera before acquiring the image, said multimedia system comprising means for the calibration of the focus and color of the acquired image with control and correction of the image focus and color by means of the detection of respectively the targeting spots and reference colors on the test-strip thus allowing to distinguish each wheal from the skin and the erythema triggered by the administration of the allergen, obtaining a precise measure of the targeted area and allowing contemporarily an accurate clinical evaluation on the kind of allergic reaction. (a) System for the acquisition of image of said wheals, said system comprising a video camera; (b) A test strip for the positioning of the allergens on a part of a patient's body, preferably the forearm; (c) A multimedia system comprising a software having the following functions: - optimization of the acquired images - identification of the wheals - interactive measuring of the form and dimensions of the identified wheals wherein said test strip comprises: cut-outs used for (i) administered allergens, (ii) reference allergens, characterised in that the test strip further comprises: targeting spots and a reference-color scale, said targeting spots and reference-color scale being provided for allowing to calibrate respectively the focusing and the color of the video camera before acquiring the image, said multimedia system comprising means for the calibration of the focus and color of the acquired image with control and correction of the image focus and color by means of the detection of respectively the targeting spots and reference colors on the test-strip thus allowing to distinguish each wheal from the skin and the erythema triggered by the administration of the allergen, obtaining a precise measure of the targeted area and allowing contemporarily an accurate clinical evaluation on the kind of allergic reaction. - optimization of the acquired images - identification of the wheals - interactive measuring of the form and dimensions of the identified wheals cut-outs used for (i) administered allergens, (ii) reference allergens, (i) administered allergens, (ii) reference allergens, characterised in that the test strip further comprises: targeting spots and a reference-color scale, said targeting spots and reference-color scale being provided for allowing to calibrate respectively the focusing and the color of the video camera before acquiring the image, said multimedia system comprising means for the calibration of the focus and color of the acquired image with control and correction of the image focus and color by means of the detection of respectively the targeting spots and reference colors on the test-strip thus allowing to distinguish each wheal from the skin and the erythema triggered by the administration of the allergen, obtaining a precise measure of the targeted area and allowing contemporarily an accurate clinical evaluation on the kind of allergic reaction. targeting spots and a reference-color scale, said targeting spots and reference-color scale being provided for allowing to calibrate respectively the focusing and the color of the video camera before acquiring the image, said multimedia system comprising means for the calibration of the focus and color of the acquired image with control and correction of the image focus and color by means of the detection of respectively the targeting spots and reference colors on the test-strip thus allowing to distinguish each wheal from the skin and the erythema triggered by the administration of the allergen, obtaining a precise measure of the targeted area and allowing contemporarily an accurate clinical evaluation on the kind of allergic reaction.