mhurhangee/ep-ind-claims huggingface dataset:
Method for making shaped cutouts in the casing of a metal cylinder, such as a roll, using a fluting machine, wherein said fluting machine comprises: • a frame, provided with: ∘ a cylinder holder, for the rotatable positioning of the metal cylinder; ∘ rotation means, for rotating the cylinder holder about a rotation axis; and ∘ a guide extending parallel to the rotation axis; • a metal-cutting tool, movable over the guide, for making shaped cutouts in the metal cylinder; and provided with a drive mechanism, for moving the metal-cutting tool over the guide; • wherein the metal-cutting tool is arranged to remove a portion of the metal cylinder while moving over the guide; • wherein the metal-cutting tool is provided with a tooling holder for a metal-cutting element, such as a chisel or a milling cutter; • wherein the tooling holder is arranged to hold at least two metal-cutting elements, wherein the tooling holder is rotatable, the method is characterised in that: the metal tooling cutting tool is further provided with a detection device, for detecting the state of the metal-cutting elements in the tooling holder, the method is further characterised by: comprising a step of rotating the tooling holder when the metal-cutting tool has executed a predefined number of movements relative to the frame, or by comprising a step of rotating the tooling holder when the state of at least one of the metal-cutting elements reaches a predefined state. • a frame, provided with: ∘ a cylinder holder, for the rotatable positioning of the metal cylinder; ∘ rotation means, for rotating the cylinder holder about a rotation axis; and ∘ a guide extending parallel to the rotation axis; ∘ a cylinder holder, for the rotatable positioning of the metal cylinder; ∘ rotation means, for rotating the cylinder holder about a rotation axis; and ∘ a guide extending parallel to the rotation axis; • a metal-cutting tool, movable over the guide, for making shaped cutouts in the metal cylinder; and provided with a drive mechanism, for moving the metal-cutting tool over the guide; • wherein the metal-cutting tool is arranged to remove a portion of the metal cylinder while moving over the guide; • wherein the metal-cutting tool is provided with a tooling holder for a metal-cutting element, such as a chisel or a milling cutter; • wherein the tooling holder is arranged to hold at least two metal-cutting elements, wherein the tooling holder is rotatable, the method is characterised in that: the metal tooling cutting tool is further provided with a detection device, for detecting the state of the metal-cutting elements in the tooling holder, the method is further characterised by: comprising a step of rotating the tooling holder when the metal-cutting tool has executed a predefined number of movements relative to the frame, or by comprising a step of rotating the tooling holder when the state of at least one of the metal-cutting elements reaches a predefined state.
A check valve comprising made integrally a body and a seat with an inlet channel, guides arranged in the body, as well as a stem with a plate gate installed in the guides holes coaxially with the seat, arranged with a possibility of an axial displacement and interaction with the seat during action of a flow from the side of outlet channel, which is designed in a form of an outlet pipe, wherein the guides are made with a recess for a placement of one end of the outlet pipe, on which concentrically and coaxially with the guides a collet clamp and a nut are put, made with a tapered boring crimping the collet clamp and with a threaded hole mated with a thread cut provided on the body, wherein the guides are made in a form of two guide bushings successively installed in the body each of which has inclined partitions converging towards a central ring where the hole for the stem is provided, and a peripheral cylindrical band with an outer surface for installation in the body and with an inner surface for a placement of the output pipe connected with windows formed between the partitions with the seat, wherein the guide bushings are installed coaxially and faced with each other by bases of the inclined partitions connected with inner surface of the peripheral band by radial ribs.
A clustered system comprising a set of connected computers working as a single system, said set comprising a first nodes and a second node arranged for communicating with each other via a lossless Ethernet network, whereby said first and said second node exchange data storage traffic of a clustered file system between each other via an IP protocol over said lossless Ethernet network, said clustered file system being a file system which is simultaneously mountable via multiple servers and arranged for performing on said data storage traffic reading and writing operations displaying a many-to-one traffic pattern, whereby said data storage traffic comprises different data traffic flows of the same type.
A computing device comprising: a support plate; a first hinge coupled to a first end of the support plate; a second hinge coupled to a second end of the support plate; a first display coupled to the first hinge, and includes a cavity configured behind the first display to receive at least the support plate; a physical keyboard coupled to the second hinge; and a second display coupled to the second hinge, the physical keyboard and the second display rotatable about the second hinge, wherein the first display is coupled to the support plate at a first location, and the physical keyboard is coupled to the support plate at a second location, the second location closer to the second display than the first location; and wherein the physical keyboard is rotatable about the second hinge to be movable between a stowed position and a deployed position, where in the stowed position, the physical keyboard is rotated to be received, together with the support plate, in the cavity of the first display, and in the deployed position, the physical keyboard is rotated from the stowed position to be disposed at least partially on the second display. a support plate; a first hinge coupled to a first end of the support plate; a second hinge coupled to a second end of the support plate; a first display coupled to the first hinge, and includes a cavity configured behind the first display to receive at least the support plate; a physical keyboard coupled to the second hinge; and a second display coupled to the second hinge, the physical keyboard and the second display rotatable about the second hinge, wherein the first display is coupled to the support plate at a first location, and the physical keyboard is coupled to the support plate at a second location, the second location closer to the second display than the first location; and wherein the physical keyboard is rotatable about the second hinge to be movable between a stowed position and a deployed position, where in the stowed position, the physical keyboard is rotated to be received, together with the support plate, in the cavity of the first display, and in the deployed position, the physical keyboard is rotated from the stowed position to be disposed at least partially on the second display.
GLP-1R/GCGR dual target agonist polypeptides compound for use in preventing or treating non-alcoholic fatty liver diseases (NAFLDs), the polypeptides compound comprising a parent peptide represented by the following amino acid sequence: wherein, R 1 = -NH2; Xaa2 = Aib, or D-Ser; Xaa10 = Lys or Tyr; Xaa13 = Lys or Tyr; Xaa16 = Aib, Lys or Glu; Xaa17 = Arg; Xaa18 = Arg; Xaa20 = Gln; Xaa21 =Asp; Xaa23 = Val; Xaa24 = Gln; Xaa27 = Met, Leu, or Nle; Xaa28 = Asp, or Asn; Xaa29 = Thr or is absent; Xaa30 = Gly; Xaa31 = Gly; Xaa32 = Pro; Xaa33 = Ser; Xaa34 = Ser; Xaa35 = Gly; Xaa36 = Ala; Xaa37 = Pro; Xaa38 = Pro; Xaa39 = Pro; Xaa40 = Ser; in the amino acid sequence of the parent peptide, Xaa10, or Xaa16 is Lys, the side chain of the at least one Lys or the Lys at position 12 of the sequence is attached to a lipophilic substituent in such a way that a carboxyl group of the lipophilic substituent forms an amide bond with an amino of a bridging group, the bridging group is attached to the parent peptide by means of a carboxyl group of the amino acid residue of the bridging group which forms an amide bond with the amino of the side chain of the Lys at position 10,12 or 16 of the sequence of the parent peptide, the bridging group is Glu- m or Asp- m or m, wherein m is an integer of 2-10; the lipophilic substituent is an acyl group selected from CH 3 (CH 2) n CO- or HOOC(CH 2) n CO-, wherein n is an integer of 10-24. wherein, R 1 = -NH2; Xaa2 = Aib, or D-Ser; Xaa10 = Lys or Tyr; Xaa13 = Lys or Tyr; Xaa16 = Aib, Lys or Glu; Xaa17 = Arg; Xaa18 = Arg; Xaa20 = Gln; Xaa21 =Asp; Xaa23 = Val; Xaa24 = Gln; Xaa27 = Met, Leu, or Nle; Xaa28 = Asp, or Asn; Xaa29 = Thr or is absent; Xaa30 = Gly; Xaa31 = Gly; Xaa32 = Pro; Xaa33 = Ser; Xaa34 = Ser; Xaa35 = Gly; Xaa36 = Ala; Xaa37 = Pro; Xaa38 = Pro; Xaa39 = Pro; Xaa40 = Ser;
A phenylimidazole compound represented by the following General Formula: wherein R 1 represents a hydrogen atom, a phenyl C 1-6 alkyl group or a pyridyl C 1-6 alkyl group, and the benzene ring and the pyridine ring are optionally substituted with 1 or 2 substituents selected from the group consisting of halogen atoms, cyano group and halogen-substituted C 1-6 alkyl groups. One of R 2 and R 3 represents a hydrogen atom and the other represents a C 1-6 alkoxy group. R 4 represents a C 1-6 alkyl group, a furyl group, a thienyl group or a phenyl group optionally substituted with 1 or 2 substituents selected from the group consisting of C 1-6 alkyl groups, C 1-6 alkoxy groups, halogen atoms, carboxyl group, C 1-6 alkoxycarbonyl groups and halogen-substituted C 1-6 alkyl groups. R 5 and R 6 are the same or different, and represent a hydrogen atom or a C 1-6 alkyl group. R 7 and R 8 are the same or different, and represent a hydrogen atom or a C 1-6 alkoxy group. However, when R 1 represents an unsubstituted phenyl C 1-6 alkyl group, R 2 represents a C 1-6 alkoxy group, R 3 represents a hydrogen atom, R 4 represents an unsubstituted phenyl group or a phenyl group having 1 or 2 halogen-substituted C 1-6 alkyl groups, and R 5 represents a hydrogen atom, R 6 is not a hydrogen atom.
A method of wireless communication performed by a user equipment, UE, comprising: identifying a downlink transmission time interval, TTI, of a time-division duplex, TDD, configured carrier; receiving an indication of a duration of the downlink TTI during a first symbol of the downlink TTI; receiving an indication of a duration of an uplink TTI that adjacently follows the downlink TTI, wherein the indication of the duration of the uplink TTI is received during a last symbol of the downlink TTI; and communicating with the base station based at least in part on the indication of the duration of the downlink TTI and the indication of the duration of the uplink TTI; wherein the communicating with the base station comprises switching a radio from a downlink configuration to an uplink configuration upon reception of the indication of the duration of the uplink TTI, if said duration is not zero. identifying a downlink transmission time interval, TTI, of a time-division duplex, TDD, configured carrier; receiving an indication of a duration of the downlink TTI during a first symbol of the downlink TTI; receiving an indication of a duration of an uplink TTI that adjacently follows the downlink TTI, wherein the indication of the duration of the uplink TTI is received during a last symbol of the downlink TTI; and communicating with the base station based at least in part on the indication of the duration of the downlink TTI and the indication of the duration of the uplink TTI; wherein the communicating with the base station comprises switching a radio from a downlink configuration to an uplink configuration upon reception of the indication of the duration of the uplink TTI, if said duration is not zero.
Hydrodynamic coupling device, in particular torque converter, comprising a housing arrangement which is filled or can be filled with fluid, an impeller which can be rotated with the housing arrangement about a rotational axis, a turbine wheel which is arranged in the housing arrangement and can be rotated with an output member about the rotational axis, a lock-up clutch for producing a torque transmission connection between the housing arrangement and the output member, a torsional vibration damping arrangement with an input region and an output region, a first torque transmission path being provided between the input region and the output region and, parallel thereto, a second torque transmission path and a coupling arrangement for superimposing the torques which are conducted via the torque transmission paths (46, 48) being provided, the torsional vibration damping arrangement comprising, furthermore, a phase shifter arrangement at least in the first torque transmission path in order to produce a phase shift of rotational non-uniformities which are conducted via the first torque transmission path with regard to rotational non-uniformities which are conducted via the second torque transmission path, characterized in that the torsional vibration damping arrangement is arranged in such a way that the entire torque flow via the torsional vibration damping arrangement is interrupted by way of an interruption of one of the torque transmission paths (46, 48).
A compound of Formula I: or a pharmaceutically acceptable salt, solvate, or stereoisomer thereof, wherein: X is C(=O) or CH 2; YisO; m is an integer of 0, 1, 2, or 3; R 1 is hydrogen; R 2 is -NO 2, C 0-6 alkyl-(5 to 10 membered heteroaryl), C 0-6 alkyl-(5 to 6 membered heterocyclyl), C 0-6 alkyl-OH, C 0-4 alkyl-NH 2, -NHCO-C 1-6 alkyl, -OR 21, or -(CH 2 -Z) 0-2 -(5 to 10 membered heteroaryl), where each heteroaryl and heterocyclyl is optionally substituted with one or more C 1-6 alkyl; R 3 is hydrogen, halogen, -NO 2, C 0-6 alkyl-(5 to 10 membered heteroaryl), C 0-6 alkyl-(5 to 6 membered heterocyclyl), C 0-6 alkyl-OH, C 0-4 alkyl-NH 2, -NHCO-C 1-6 alkyl, -OR 21, or -(CH 2 -Z) 0-2 -(5 to 10 membered heteroaryl), where each heteroaryl and heterocyclyl is optionally substituted with one or more Alkyl; R 21 is C 6-10 aryl, 5 to 10 membered heteroaryl, 5 to 6 membered heterocyclyl, or -CO(CH 2) 0-2 R 22, wherein the aryl, heteroaryl, and heterocyclyl are each optionally substituted with one or more C 1-6 alkyl; R 22 is -NH 2 or 5 to 6 membered heterocyclyl; and Z is CH 2, NH, or O; with the proviso that when R 3 is halogen, then R 2 is C 0-6 alkyl-(5-6 membered heterocyclyl). X is C(=O) or CH 2; YisO; m is an integer of 0, 1, 2, or 3; R 1 is hydrogen; R 2 is -NO 2, C 0-6 alkyl-(5 to 10 membered heteroaryl), C 0-6 alkyl-(5 to 6 membered heterocyclyl), C 0-6 alkyl-OH, C 0-4 alkyl-NH 2, -NHCO-C 1-6 alkyl, -OR 21, or -(CH 2 -Z) 0-2 -(5 to 10 membered heteroaryl), where each heteroaryl and heterocyclyl is optionally substituted with one or more C 1-6 alkyl; R 3 is hydrogen, halogen, -NO 2, C 0-6 alkyl-(5 to 10 membered heteroaryl), C 0-6 alkyl-(5 to 6 membered heterocyclyl), C 0-6 alkyl-OH, C 0-4 alkyl-NH 2, -NHCO-C 1-6 alkyl, -OR 21, or -(CH 2 -Z) 0-2 -(5 to 10 membered heteroaryl), where each heteroaryl and heterocyclyl is optionally substituted with one or more Alkyl; R 21 is C 6-10 aryl, 5 to 10 membered heteroaryl, 5 to 6 membered heterocyclyl, or -CO(CH 2) 0-2 R 22, wherein the aryl, heteroaryl, and heterocyclyl are each optionally substituted with one or more C 1-6 alkyl; R 22 is -NH 2 or 5 to 6 membered heterocyclyl; and Z is CH 2, NH, or O; with the proviso that when R 3 is halogen, then R 2 is C 0-6 alkyl-(5-6 membered heterocyclyl).
A lighting system comprising: - a power supply apparatus which has a power generation unit, which is suitable for generating a direct current, and an energy storage unit for storing energy from the power generation unit, and - a lighting means unit which emits white light and comprises a plurality of lighting means, which can be operated with a direct current, and which is connected to the energy storage unit in order to be supplied with a direct current, wherein no apparatus for converting a direct current into an alternating current or an alternating current into a direct current is arranged between the power generation unit and the lighting means, wherein the power supply apparatus and the lighting means unit have a common control apparatus which is connected to a weather station and/or is designed to receive weather data via the Internet, and the control apparatus is designed to control the lighting means unit as a function of a prediction for the amount of energy which can be expected to be input into the power generation unit in the future, characterized in that - the lighting means are colored LEDs, - the generation of white light is achieved by additive color mixing of the colored LEDs, - the control device is designed to change a color temperature of the lighting means unit which emits white light, such that a predefined light intensity is achieved with a relatively low level of power consumption. - a power supply apparatus which has a power generation unit, which is suitable for generating a direct current, and an energy storage unit for storing energy from the power generation unit, and - a lighting means unit which emits white light and comprises a plurality of lighting means, which can be operated with a direct current, and which is connected to the energy storage unit in order to be supplied with a direct current, wherein no apparatus for converting a direct current into an alternating current or an alternating current into a direct current is arranged between the power generation unit and the lighting means, wherein the power supply apparatus and the lighting means unit have a common control apparatus which is connected to a weather station and/or is designed to receive weather data via the Internet, and the control apparatus is designed to control the lighting means unit as a function of a prediction for the amount of energy which can be expected to be input into the power generation unit in the future, characterized in that - the lighting means are colored LEDs, - the generation of white light is achieved by additive color mixing of the colored LEDs, - the control device is designed to change a color temperature of the lighting means unit which emits white light, such that a predefined light intensity is achieved with a relatively low level of power consumption.
A method performed by a location server in a Long Term Evolution Positioning Protocol, LPP, control plane environment, the method comprising: generating a message containing assistance data to be processed by a mobile terminal and an acknowledgement request field; determining whether the message is solicited by the mobile terminal; setting, based on said determining, the acknowledgement request field in the message to indicate acknowledgement is required when the message is solicited by the mobile terminal and to indicate acknowledgement is not required when the message is unsolicited by the mobile terminal; and transmitting the message from the location server to the mobile terminal. generating a message containing assistance data to be processed by a mobile terminal and an acknowledgement request field; determining whether the message is solicited by the mobile terminal; setting, based on said determining, the acknowledgement request field in the message to indicate acknowledgement is required when the message is solicited by the mobile terminal and to indicate acknowledgement is not required when the message is unsolicited by the mobile terminal; and transmitting the message from the location server to the mobile terminal.
A method for wireless communications, comprising: determining (1905; 2005; 2105; 2205; 2305) a first subframe structure having a first subframe duration for communicating in a first carrier; determining (1910; 2010; 2110; 2210; 2310) a second subframe structure having a second subframe duration for communicating in a second carrier, the second subframe duration being different from the first subframe duration; allocating resources using at least a pair of adjacent resource blocks, RBs, of the second subframe structure, the adjacent RBs of the second subframe structure functioning together as a single RB of the first subframe structure; and communicating (1915; 2020; 2120; 2220; 2315, 2320) with at least one node using at least the second subframe structure having the second subframe duration based on the allocating. determining (1905; 2005; 2105; 2205; 2305) a first subframe structure having a first subframe duration for communicating in a first carrier; determining (1910; 2010; 2110; 2210; 2310) a second subframe structure having a second subframe duration for communicating in a second carrier, the second subframe duration being different from the first subframe duration; allocating resources using at least a pair of adjacent resource blocks, RBs, of the second subframe structure, the adjacent RBs of the second subframe structure functioning together as a single RB of the first subframe structure; and communicating (1915; 2020; 2120; 2220; 2315, 2320) with at least one node using at least the second subframe structure having the second subframe duration based on the allocating.
A device for coupling to a connector (16a, 16b) on an ear cup (12a, 12b) of a headset, the device comprising: a mating connector including a crossover conductor coupled to a first and a second terminal within the mating connector; a power conductor and a ground conductor coupled to respective third and fourth terminals in the mating connector; and an accessory electronic device (100, 102) adapted to be powered by power received from the headset over the third and fourth terminal within the mating connector when the device is coupled to the headset, wherein the accessory electronic device comprises: a position sensor for determining a position of the device; and a data connection outputting data from the position sensor. a mating connector including a crossover conductor coupled to a first and a second terminal within the mating connector; a power conductor and a ground conductor coupled to respective third and fourth terminals in the mating connector; and an accessory electronic device (100, 102) adapted to be powered by power received from the headset over the third and fourth terminal within the mating connector when the device is coupled to the headset,
A respiratory protection system which comprises a heterogeneous catalyst system, comprising: a plurality of composite particles, wherein said composite particles are derived from ingredients comprising nanoporous guest particles with a size less than 100 micrometers and host particles with a size greater than 590 micrometers (30 mesh), and wherein the composite particles comprise gold clusters with cluster dimensions from 0.5 to 50 nm deposited onto the composite particles using physical vapor deposition; and wherein the respiratory protection system is a mask that removes CO from breathing air. a plurality of composite particles, wherein said composite particles are derived from ingredients comprising nanoporous guest particles with a size less than 100 micrometers and host particles with a size greater than 590 micrometers (30 mesh), and wherein the composite particles comprise gold clusters with cluster dimensions from 0.5 to 50 nm deposited onto the composite particles using physical vapor deposition;
A complete media formulation comprising the following components: albumin, an iron carrier, glutamine, hyaluronidase at a concentration of about 1 to about 100 μg/ml, fibroblast growth factor, a salt or mineral, and essential amino acids, at an osmolarity of about 220-330 mOsm/Liter.