mhurhangee/ep-ind-claims huggingface dataset:
A droplet deposition head comprising one or more actuator components, an actuator component including nozzles arranged for ejecting fluid, the head including a datum surface arrangement for alignment of the head relative to an external mounting component (100; 150) in either a vertical mounting mode in which the head is held against a vertical mounting plate or a horizontal mounting mode where the head is held against a horizontal mounting plate, the datum surface arrangement comprising at least seven datum surfaces (x1; y1, y2, y3; z1, z2, z3) provided on the head; wherein five of the at least seven datum surfaces are provided for alignment in both vertical and horizontal mounting modes; and wherein a sixth datum surface is provided for alignment exclusively in said horizontal mounting mode and a seventh datum surface is provided for alignment exclusively in said vertical mounting mode.
A carrier arrangement comprising: - a carrier element having a carrier surface, - a plurality of supporting elements attached to the carrier element, wherein each supporting element has a supporting surface extending from the carrier surface of the carrier element and being adapted to interact with a first surface of a component to be repaired, - a plurality of clamping elements, wherein at least a part of the clamping elements are releasably attachable to the carrier element in such a manner that a clamping surface of the clamping elements, which is adapted to interact with a second surface of a component to be repaired, faces the supporting surface of an associated supporting element so as to sandwich the component to be repaired therebetween in such a manner that the component is fixed to the carrier element with a repair site of the component facing away from the carrier surface of the carrier element, and - a fastening device adapted to interact with a corresponding fastening device of an apparatus for repairing components by selectively irradiating layers of a raw material powder applied to the repair sites of the components with electromagnetic or particle radiation, wherein at least a part of the supporting elements are attached to the carrier element in a row pattern, and wherein at least a part of the clamping elements are releasably attachable to respective supporting elements arranged in a first row of the row pattern in such a manner that their clamping surfaces face the supporting surfaces of their associated supporting elements which are arranged in an adjacent row of the row pattern. - a carrier element having a carrier surface, - a plurality of supporting elements attached to the carrier element, wherein each supporting element has a supporting surface extending from the carrier surface of the carrier element and being adapted to interact with a first surface of a component to be repaired, - a plurality of clamping elements, wherein at least a part of the clamping elements are releasably attachable to the carrier element in such a manner that a clamping surface of the clamping elements, which is adapted to interact with a second surface of a component to be repaired, faces the supporting surface of an associated supporting element so as to sandwich the component to be repaired therebetween in such a manner that the component is fixed to the carrier element with a repair site of the component facing away from the carrier surface of the carrier element, and - a fastening device adapted to interact with a corresponding fastening device of an apparatus for repairing components by selectively irradiating layers of a raw material powder applied to the repair sites of the components with electromagnetic or particle radiation,
Recombinant antibody, comprising a.) a binding unit of an antibody that specifically binds to an epitope of a human La protein, as well as b.) a binding unit - of an antibody that binds specifically to an effector cell or - of a ligand that binds specifically to an effector cell, whereas the antibody that binds specifically to an effector cell is direct against a surface structure selected from CD3, CD8, CD4, CD25, CD28, CD16, NKG2D, NKp46, NKp44 and activating KIR receptors, whereas the ligand that binds specifically to an effector cell, is selected from ULB-Ps, MICA, MICB, IL2 and IL15. a.) a binding unit of an antibody that specifically binds to an epitope of a human La protein, as well as b.) a binding unit - of an antibody that binds specifically to an effector cell or - of a ligand that binds specifically to an effector cell, whereas the antibody that binds specifically to an effector cell is direct against a surface structure selected from CD3, CD8, CD4, CD25, CD28, CD16, NKG2D, NKp46, NKp44 and activating KIR receptors, whereas the ligand that binds specifically to an effector cell, is selected from ULB-Ps, MICA, MICB, IL2 and IL15. - of an antibody that binds specifically to an effector cell or - of a ligand that binds specifically to an effector cell,
A seal assembly comprising a layered structure consisting of - a first layer (9,) of a base material, - a second layer of thermal insulating material on top of the first layer (9,) and - a third layer (11,) of the base material or of an oxidation resistant material on top of the layer of thermal insulation, - wherein this layered structure (9, 10, 11) is constructed as a connector plate, characterized in that - the connector plate is connected on two sides to a spring side support, this spring side support is an E-seal, the spring side support is welded to the connector plate and within the spring side support or within the E-seal are arranged cooling holes. - a first layer (9,) of a base material, - a second layer of thermal insulating material on top of the first layer (9,) and - a third layer (11,) of the base material or of an oxidation resistant material on top of the layer of thermal insulation, - wherein this layered structure (9, 10, 11) is constructed as a connector plate, characterized in that - the connector plate is connected on two sides to a spring side support, this spring side support is an E-seal, the spring side support is welded to the connector plate and within the spring side support or within the E-seal are arranged cooling holes.
A device for detecting the presence of an arsenic derivative analyte in a sample, comprising (i) at least one electrode, (ii) an arsenite oxidase enzyme, and (iii) a first redox mediator; characterised in that the first redox mediator is cytochrome C, and the device further comprises a second redox mediator, wherein the second redox mediator is ferricyanide. (i) at least one electrode, (ii) an arsenite oxidase enzyme, and (iii) a first redox mediator;
A multigrade additive composition for asphalts which consists essentially of a product obtained by reacting: a) at least one saponifiable organic acid; b) at least one resin acid; c) at least one unsaturated organic compound; and d) an alkali metal base, and removing water during the reaction so that the percentage of water in the final reaction product is from 0.2 to 1.5 wt. %. a) at least one saponifiable organic acid; b) at least one resin acid; c) at least one unsaturated organic compound; and d) an alkali metal base,
A complex comprising: a) a nanoparticle-nucleic acid conjugate; b) a Type II or a Type V CRISPR system comprising: i) a Cas9 polypeptide or a Cpfl polypeptide; and ii) a guide RNA; and c) an endosomal disruptive polymer. a) a nanoparticle-nucleic acid conjugate; b) a Type II or a Type V CRISPR system comprising: i) a Cas9 polypeptide or a Cpfl polypeptide; and ii) a guide RNA; and i) a Cas9 polypeptide or a Cpfl polypeptide; and ii) a guide RNA; and c) an endosomal disruptive polymer.
A device for urinary catheterisation comprising: a catheter 10 having an elongate body 12 provided with a distal tip 16, a proximal end 18, and a drainage channel 14 and a separate guidewire channel 32 extending therethrough; a guidewire 38 extending through the guidewire channel for guiding the catheter upon insertion; and a lubrication port 34 at or towards the proximal end of the elongate body, the lubrication port comprising a side arm in fluid communication with the guidewire channel for the introduction of a guidewire lubrication fluid into the guidewire channel; wherein the drainage channel extends along the centre of the elongate body and the guidewire channel extends parallel to the drainage channel along one side of the elongate body. a catheter 10 having an elongate body 12 provided with a distal tip 16, a proximal end 18, and a drainage channel 14 and a separate guidewire channel 32 extending therethrough; a guidewire 38 extending through the guidewire channel for guiding the catheter upon insertion; and a lubrication port 34 at or towards the proximal end of the elongate body, the lubrication port comprising a side arm in fluid communication with the guidewire channel for the introduction of a guidewire lubrication fluid into the guidewire channel; wherein the drainage channel extends along the centre of the elongate body and the guidewire channel extends parallel to the drainage channel along one side of the elongate body.
A control system configured to control priming of a catheter assembly, the control system comprising one or more hardware processors, the control system configured to: generate a first user interface including a visual indication of a first instruction corresponding to priming of the catheter assembly to remove gas from the catheter assembly prior to a treatment procedure; monitor one or more sensors (902, 904, 906, 908) of a fluid handling system, the fluid handling system configured to prime the catheter assembly to remove the gas; determine a system condition based in part on the monitoring of the one or more sensors (902, 904, 906, 908); and control an operation of a component of the fluid handling system based on the determined system condition, wherein the controlling of the operation comprises controlling, based on the determined system condition, directing of fluid distally through the catheter assembly to remove the gas. generate a first user interface including a visual indication of a first instruction corresponding to priming of the catheter assembly to remove gas from the catheter assembly prior to a treatment procedure; monitor one or more sensors (902, 904, 906, 908) of a fluid handling system, the fluid handling system configured to prime the catheter assembly to remove the gas; determine a system condition based in part on the monitoring of the one or more sensors (902, 904, 906, 908); and control an operation of a component of the fluid handling system based on the determined system condition, wherein the controlling of the operation comprises controlling, based on the determined system condition, directing of fluid distally through the catheter assembly to remove the gas.
A balloon catheter assembly, comprising: an elongate catheter tube, including a lumen, having a first cross sectional area; a wire, extending through said lumen,; and an inflatable balloon, mountably associated, at a rearward end, thereof, with said elongate catheter tube, and mountably associated, at a forward end, thereof, with said wire,; said elongate catheter tube, being formed with a plurality of balloon inflation apertures, communicating with said lumen,, said plurality of balloon inflation apertures, including at least two apertures being arranged at different azimuthal locations along said catheter tube, underlying said balloon,, and said balloon, having an inflated state and a corresponding deflated state wherein at least a first portion of said balloon, is capable of being twisted relative to at least a second portion of said balloon,, resulting in at least partial blockage of at least one but not all of said plurality of balloon inflation apertures,; characterized in that: said plurality of balloon inflation apertures, have a total aperture cross sectional area which exceeds said first cross sectional area of said lumen,; and the inflated state of said balloon, has a ratio of maximum inflated diameter to length of more than 0.4. an elongate catheter tube, including a lumen, having a first cross sectional area; a wire, extending through said lumen,; and an inflatable balloon, mountably associated, at a rearward end, thereof, with said elongate catheter tube, and mountably associated, at a forward end, thereof, with said wire,; said elongate catheter tube, being formed with a plurality of balloon inflation apertures, communicating with said lumen,, said plurality of balloon inflation apertures, including at least two apertures being arranged at different azimuthal locations along said catheter tube, underlying said balloon,, and said balloon, having an inflated state and a corresponding deflated state wherein at least a first portion of said balloon, is capable of being twisted relative to at least a second portion of said balloon,, resulting in at least partial blockage of at least one but not all of said plurality of balloon inflation apertures,; characterized in that: said plurality of balloon inflation apertures, have a total aperture cross sectional area which exceeds said first cross sectional area of said lumen,; and the inflated state of said balloon, has a ratio of maximum inflated diameter to length of more than 0.4. said plurality of balloon inflation apertures, have a total aperture cross sectional area which exceeds said first cross sectional area of said lumen,; and the inflated state of said balloon, has a ratio of maximum inflated diameter to length of more than 0.4.
An aircraft assembly comprising: a wing component comprising three fastening locations arranged in a triangle such that they define a plane; an engine mounting pylon component connected to the wing component by three tension fasteners, wherein each of the tension fasteners passes through a different one of the fastening locations; characterised in that the wing component comprises three first spherical surfaces (14a, 14b, 14c) positioned such that the centre of each first spherical surface is at a different one of the fastening locations, and wherein the engine mounting pylon component comprises three second spherical surfaces (13a, 13b, 13c) having equal and opposite curvature to the first spherical surfaces, each of the second spherical surfaces being in contact with a different one of the first spherical surfaces. a wing component comprising three fastening locations arranged in a triangle such that they define a plane; an engine mounting pylon component connected to the wing component by three tension fasteners, wherein each of the tension fasteners passes through a different one of the fastening locations; characterised in that the wing component comprises three first spherical surfaces (14a, 14b, 14c) positioned such that the centre of each first spherical surface is at a different one of the fastening locations, and wherein the engine mounting pylon component comprises three second spherical surfaces (13a, 13b, 13c) having equal and opposite curvature to the first spherical surfaces, each of the second spherical surfaces being in contact with a different one of the first spherical surfaces.
A method of controlling storage of electrical energy by charging and discharging an energy storage device in response to pricing data indicative of future prices of electrical energy over time and energy losses caused by charging and discharging the energy storage device, the method comprising: detecting alternating candidate charging and discharging occasions with respect to the pricing data by selecting a next occurrence of a locally minimum price in the pricing data as a candidate charging occasion or a next occurrence of a locally maximum price in the pricing data as a candidate discharging occasion; validating a candidate charging or discharging occasion if the price difference between that candidate charging or discharging occasion and another later price in the pricing data is greater than the value of the energy losses caused by charging and discharging the energy storage device, a candidate charging or discharging occasion being validated if: P D > P C / Eff, where P D represents the price at the discharge occasion, P C represents the price at the charging occasion, and Eff represents the efficiency of the charging and discharging of the energy storage device such that Eff is equal to the ratio of energy retrieved at discharging to energy input at charging; and charging and discharging the energy storage device at the validated charging and discharging occasions, respectively. detecting alternating candidate charging and discharging occasions with respect to the pricing data by selecting a next occurrence of a locally minimum price in the pricing data as a candidate charging occasion or a next occurrence of a locally maximum price in the pricing data as a candidate discharging occasion; validating a candidate charging or discharging occasion if the price difference between that candidate charging or discharging occasion and another later price in the pricing data is greater than the value of the energy losses caused by charging and discharging the energy storage device, a candidate charging or discharging occasion being validated if: P D > P C / Eff, where P D represents the price at the discharge occasion, P C represents the price at the charging occasion, and Eff represents the efficiency of the charging and discharging of the energy storage device such that Eff is equal to the ratio of energy retrieved at discharging to energy input at charging; and charging and discharging the energy storage device at the validated charging and discharging occasions, respectively.
An assay for determining the likelihood of late onset Alzheimer's disease (LOAD) in a subject in need thereof comprising: i) assaying a sample obtained from the subject to determine the level of amyloid precursor protein -specific CD8+ T cells, wherein assaying the sample comprises using an MHC/APP peptide complex to determine the level of APP-specific CD8+ T cells; and ii) determining that the subject has a likelihood of LOAD if the level of the APP-specific CD8+ T cells are higher relative to the reference value, or determining that the subject has a decreased likelihood of LOAD if the level of the APP-specific CD8+ T cells are same as or lower relative to the reference value, wherein the reference value is the mean or median level of APP-specific CD8+ T cells in a population of subjects that do not have LOAD; or wherein the reference level is the mean or median level of APP-specific CD8+ T cells in the sample obtained from the subject at a different time point. i) assaying a sample obtained from the subject to determine the level of amyloid precursor protein -specific CD8+ T cells, wherein assaying the sample comprises using an MHC/APP peptide complex to determine the level of APP-specific CD8+ T cells; and ii) determining that the subject has a likelihood of LOAD if the level of the APP-specific CD8+ T cells are higher relative to the reference value, or determining that the subject has a decreased likelihood of LOAD if the level of the APP-specific CD8+ T cells are same as or lower relative to the reference value, wherein the reference value is the mean or median level of APP-specific CD8+ T cells in a population of subjects that do not have LOAD; or wherein the reference level is the mean or median level of APP-specific CD8+ T cells in the sample obtained from the subject at a different time point.
Use of pure magnesium or magnesium alloy for preparing a bioresorbable implant for generating or regenerating ligaments within a mammal, wherein the implant itself induces fibrosis within the body of the mammal, and the fibrosis induced by the implant contributes to the generation or regeneration of the ligaments, wherein the pure magnesium has a purity of 99.95% to 99.9999%, and the magnesium alloy comprises 0-16 wt% aluminum, 0-5 wt% calcium, 0-8 wt% rare earth metals, 0-5 wt% lithium and 0-5 wt% manganese.
A quarter wave plate (100; 400) comprising at least one body of dielectric material, the or each said body having first and second end faces on opposite sides thereof; the or each body comprising a first portion (a; a', a") comprising a first number of parallel grooves (2; 42) extending inwardly of said first end face; a second portion (b; b', b") comprising a second number of parallel grooves (12; 42') extending inwardly of said second end face; the second number being identical to the first number and each groove (2, 42) of the first portion (a; a', a") being aligned with a corresponding groove (12, 42') of the second portion (b; b', b"); and a third portion (c; c', c") defined between the first and second portions; the respective depths of the first (2; 42) and second grooves (12; 42') being such that a phase difference of an odd integer multiple of quarter wavelengths is produced between first and second orthogonal components of an electromagnetic wave traversing the plate (100; 400), the first component having its E-vector parallel to the grooves (2, 12; 42, 42'), the second component having its E-vector perpendicular to the grooves (2, 12; 42, 42'); characterised in that the dielectric material has a relative dielectric constant of less than 5; and the length of the third portion (c; c', c") is not exactly an integer number of half wavelengths but varies from an integer number of half wavelengths by an amount selected to minimise the reflection coefficient at the first and second end faces. a first portion (a; a', a") comprising a first number of parallel grooves (2; 42) extending inwardly of said first end face; a second portion (b; b', b") comprising a second number of parallel grooves (12; 42') extending inwardly of said second end face; the second number being identical to the first number and each groove (2, 42) of the first portion (a; a', a") being aligned with a corresponding groove (12, 42') of the second portion (b; b', b"); and a third portion (c; c', c") defined between the first and second portions; the respective depths of the first (2; 42) and second grooves (12; 42') being such that a phase difference of an odd integer multiple of quarter wavelengths is produced between first and second orthogonal components of an electromagnetic wave traversing the plate (100; 400), the first component having its E-vector parallel to the grooves (2, 12; 42, 42'), the second component having its E-vector perpendicular to the grooves (2, 12; 42, 42'); characterised in that the dielectric material has a relative dielectric constant of less than 5; and the length of the third portion (c; c', c") is not exactly an integer number of half wavelengths but varies from an integer number of half wavelengths by an amount selected to minimise the reflection coefficient at the first and second end faces.