Method for operating a thermoregulation arrangement for controlling the temperature of a system which is in thermal contact with the thermoregulation arrangement and is arranged in particular inside a vehicle, in which method, in a reaction gas system, reaction gas is conducted from a reaction gas source into a reaction gas sink, which have a temperature control arrangement connected therebetween, wherein, in the temperature control arrangement arranged in the reaction gas system, in at least one reactor device (14, 14') comprising reaction material, heat is generated in an absorption mode and then cold is generated in a desorption mode or vice versa, wherein, in the absorption mode, reaction gas is absorbed from the reaction material while releasing heat and, in the desorption mode, reaction gas is desorbed from the reaction material while absorbing heat, and wherein a heat transfer medium for absorbing the generated heat or cold flows through the at least one reactor device (14, 14'), wherein, in the desorption mode, a first heat transfer circuit and, in the absorption mode, a second heat transfer circuit having a different, preferably higher, outlet temperature of the heat transfer medium from the reactor device (14, 14') than in the first heat transfer circuit is fluidically connected to the reactor device (14, 14'), wherein when changing from the absorption mode to the desorption mode or vice versa, the fluid connection of the reactor device (14, 14') with the second heat transfer circuit is switched over to the first heat transfer circuit or vice versa, wherein a fluid connection upstream of the reactor device (14, 14') is firstly switched over to the other heat transfer circuit (211, 211') and, after a switchover time, the fluid connection downstream of the reactor device (14, 14') is switched over to this other heat transfer circuit (211, 211'), wherein the switchover time is determined depending on a through-flow time of the heat transfer medium through at least the reactor device (14, 14'). in which method, in a reaction gas system, reaction gas is conducted from a reaction gas source into a reaction gas sink, which have a temperature control arrangement connected therebetween, wherein, in the temperature control arrangement arranged in the reaction gas system, in at least one reactor device (14, 14') comprising reaction material, heat is generated in an absorption mode and then cold is generated in a desorption mode or vice versa, wherein, in the absorption mode, reaction gas is absorbed from the reaction material while releasing heat and, in the desorption mode, reaction gas is desorbed from the reaction material while absorbing heat, and wherein a heat transfer medium for absorbing the generated heat or cold flows through the at least one reactor device (14, 14'), wherein, in the desorption mode, a first heat transfer circuit and, in the absorption mode, a second heat transfer circuit having a different, preferably higher, outlet temperature of the heat transfer medium from the reactor device (14, 14') than in the first heat transfer circuit is fluidically connected to the reactor device (14, 14'), wherein when changing from the absorption mode to the desorption mode or vice versa, the fluid connection of the reactor device (14, 14') with the second heat transfer circuit is switched over to the first heat transfer circuit or vice versa, wherein a fluid connection upstream of the reactor device (14, 14') is firstly switched over to the other heat transfer circuit (211, 211') and, after a switchover time, the fluid connection downstream of the reactor device (14, 14') is switched over to this other heat transfer circuit (211, 211'), wherein the switchover time is determined depending on a through-flow time of the heat transfer medium through at least the reactor device (14, 14').