A medical device, comprising: an elongate sheath having a proximal end, a distal end, and a lumen extending therebetween, wherein at least a portion of an actuating member is slidably disposed within the lumen, wherein a distal portion of the actuating member is operably coupled to an end-effector, and wherein a handle is disposed at the proximal end of the elongate sheath, and wherein the handle comprises: an elongate body portion defining a central bore therethrough, wherein the central bore includes a proximal opening, wherein a distal portion of the elongate body portion is operably coupled to the elongate sheath; and an actuator operably coupled to the actuating member and slidably disposed within the central bore of the elongate body portion, wherein the actuator includes a generally planar surface and an elongate tubular structure depending therefrom and configured to be received within the central bore, wherein the actuating member is configured to be received within the elongate tubular structure, wherein the actuator is configured to transition between a first longitudinal position relative to the elongate body portion and a second longitudinal position different from the first longitudinal position, wherein the actuator is fixedly coupled to an adjustable body including threads on an outer surface thereof and wherein a surface of the central bore includes threads for mating with the threads on the adjustable body. an elongate sheath having a proximal end, a distal end, and a lumen extending therebetween, wherein at least a portion of an actuating member is slidably disposed within the lumen, wherein a distal portion of the actuating member is operably coupled to an end-effector, and wherein a handle is disposed at the proximal end of the elongate sheath, and wherein the handle comprises: an elongate body portion defining a central bore therethrough, wherein the central bore includes a proximal opening, wherein a distal portion of the elongate body portion is operably coupled to the elongate sheath; and an actuator operably coupled to the actuating member and slidably disposed within the central bore of the elongate body portion, wherein the actuator includes a generally planar surface and an elongate tubular structure depending therefrom and configured to be received within the central bore, wherein the actuating member is configured to be received within the elongate tubular structure, wherein the actuator is configured to transition between a first longitudinal position relative to the elongate body portion and a second longitudinal position different from the first longitudinal position, an elongate body portion defining a central bore therethrough, wherein the central bore includes a proximal opening, wherein a distal portion of the elongate body portion is operably coupled to the elongate sheath; and an actuator operably coupled to the actuating member and slidably disposed within the central bore of the elongate body portion, wherein the actuator includes a generally planar surface and an elongate tubular structure depending therefrom and configured to be received within the central bore, wherein the actuating member is configured to be received within the elongate tubular structure, wherein the actuator is configured to transition between a first longitudinal position relative to the elongate body portion and a second longitudinal position different from the first longitudinal position, wherein the actuator is fixedly coupled to an adjustable body including threads on an outer surface thereof and wherein a surface of the central bore includes threads for mating with the threads on the adjustable body.