mhurhangee/ep-ind-claims huggingface dataset:
A method for measuring translation of a protein of interest in a biological sample comprising at least one cell, comprising: (i) providing a biological sample comprising a protein of interest; (ii) selecting at least one first codon pair which occurs in an mRNA sequence encoding the protein of interest at a frequency that is at least five-fold higher than the general frequency of said at least one first codon pair in a reference proteome or transcriptome; (iii) introducing into the biological sample at least one first tRNA FRET pair capable of reading the at least one first codon pair occurring in the mRNA sequence encoding said protein of interest at a frequency that is at least five-fold higher than the general frequency of said at least one first codon pair in a reference proteome or transcriptome; wherein one tRNA member of the at least one tRNA pair is labeled with a donor fluorophore and the other tRNA member is labeled with an acceptor fluorophore; and (iv) detecting FRET signals emitted from the biological sample, thereby measuring translation of the protein of interest. (i) providing a biological sample comprising a protein of interest; (ii) selecting at least one first codon pair which occurs in an mRNA sequence encoding the protein of interest at a frequency that is at least five-fold higher than the general frequency of said at least one first codon pair in a reference proteome or transcriptome; (iii) introducing into the biological sample at least one first tRNA FRET pair capable of reading the at least one first codon pair occurring in the mRNA sequence encoding said protein of interest at a frequency that is at least five-fold higher than the general frequency of said at least one first codon pair in a reference proteome or transcriptome; wherein one tRNA member of the at least one tRNA pair is labeled with a donor fluorophore and the other tRNA member is labeled with an acceptor fluorophore; and (iv) detecting FRET signals emitted from the biological sample, thereby measuring translation of the protein of interest.
Use of one or more silicon-containing compounds represented by Formula 1 or one or more compounds selected from the group consisting of Compounds 3 and 4 or a salt or solvate thereof, in an electrolyte: wherein, in Formula 1, X is nitrogen; R is a C1-C6 alkyl group substituted with one or more halogen atoms; R 1 is an unsubstituted C1-C6 alkyl group or a C1-C6 alkyl group substituted with one or more halogen atoms; R 2 is an unsubstituted C2-C5 alkenyl group; and R 3, and R 4 are each independently an unsubstituted C2-C5 alkyl group; X is nitrogen; R is a C1-C6 alkyl group substituted with one or more halogen atoms; R 1 is an unsubstituted C1-C6 alkyl group or a C1-C6 alkyl group substituted with one or more halogen atoms; R 2 is an unsubstituted C2-C5 alkenyl group; and R 3, and R 4 are each independently an unsubstituted C2-C5 alkyl group;
A pharmaceutical composition for use in treating breast cancer selected from mammary ductal carcinoma and lobular carcinoma which comprises the compound of the formula: or a pharmaceutically acceptable salt thereof and one or more physiologically acceptable carriers.
A filtration device for analyzes in parasitology, comprising a central body forming a plug having a first end capable of receiving a first vial, and a second end capable of receiving a second vial, said plug having a through channel opening, on the one hand, at its first end inside a tubular filter extending from said first end and, on the other hand, at the second end, characterized in that the filter comprises at least two longitudinal portions each having a different porosity.
A film mirror (1, 30) comprising: a resin substrate (2, 11); a metal reflective layer (6, 12); and a surface coating layer (3, 14) having a polymer of monomers including at least one type of fluorine-containing monomer, wherein a ratio of a number of fluorine atoms to a number of carbon atoms in a surface layer portion of the surface coating layer as expressed by F/C is 0.21 to 1.00 characterised in that, the surface coating layer (3, 14) has a Martens surface hardness of more than 100 N/mm 2 and an elastic recovery rate of 60% or more, the elastic recovery rate being (hmax - hf)/hmax wherein hmax is the maximum indentation depth and hf the indentation depth after load removal.
A non-oriented electrical steel sheet consisting of: in mass%, C: greater than 0.01% and 0.05% or less; Si: not less than 2.0% nor more than 4.0%; Mn: not less than 0.05% nor more than 0.5%; Al: not less than 0.01% nor more than 3.0%; optionally at least one selected from the group consisting of N: not less than 0.001% nor more than 0.004%; Cu: not less than 0.5% nor more than 1.5%; Sn: not less than 0.05% nor more than 0.5%; Ni: not less than 0.5% nor more than 5%; and P: not less than 0.005% nor more than 0.1%; and at least one selected from the group consisting of Ti, V, Zr, and Nb,a balance being composed of Fe and inevitable impurities, wherein when contents of Ti, V, Zr, Nb, and C (mass%) are represented as [Ti],, [Zr], [Nb], and respectively, a value of a parameter Q represented by "Q = ([Ti]/48 + /51 + [Zr]/91 + [Nb]/93)/( /12)" is not less than 0.9 nor more than 1.1, the matrix of a metal structure is a ferrite phase, the metal structure does not comprise a non-recrystallized structure, an average grain size of ferrite grains constituting the ferrite phase is not less than 10 μm nor more than 200 μm, a precipitate containing at least one selected from the group consisting of Ti, V, Zr, and Nb exists with a density of 1000 μm -3 or more in the ferrite grain, and an average grain size of the precipitate is not less than 0.002 μm nor more than 0.2 μm. in mass%, C: greater than 0.01% and 0.05% or less; Si: not less than 2.0% nor more than 4.0%; Mn: not less than 0.05% nor more than 0.5%; Al: not less than 0.01% nor more than 3.0%; C: greater than 0.01% and 0.05% or less; Si: not less than 2.0% nor more than 4.0%; Mn: not less than 0.05% nor more than 0.5%; Al: not less than 0.01% nor more than 3.0%; optionally at least one selected from the group consisting of N: not less than 0.001% nor more than 0.004%; Cu: not less than 0.5% nor more than 1.5%; Sn: not less than 0.05% nor more than 0.5%; Ni: not less than 0.5% nor more than 5%; and P: not less than 0.005% nor more than 0.1%; and at least one selected from the group N: not less than 0.001% nor more than 0.004%; Cu: not less than 0.5% nor more than 1.5%; Sn: not less than 0.05% nor more than 0.5%; Ni: not less than 0.5% nor more than 5%; and P: not less than 0.005% nor more than 0.1%; and at least one selected from the group consisting of Ti, V, Zr, and Nb,a balance being composed of Fe and inevitable impurities, wherein when contents of Ti, V, Zr, Nb, and C (mass%) are represented as [Ti],, [Zr], [Nb], and respectively, a value of a parameter Q represented by "Q = ([Ti]/48 + /51 + [Zr]/91 + [Nb]/93)/( /12)" is not less than 0.9 nor more than 1.1, the matrix of a metal structure is a ferrite phase, the metal structure does not comprise a non-recrystallized structure, an average grain size of ferrite grains constituting the ferrite phase is not less than 10 μm nor more than 200 μm, a precipitate containing at least one selected from the group consisting of Ti, V, Zr, and Nb exists with a density of 1000 μm -3 or more in the ferrite grain, and an average grain size of the precipitate is not less than 0.002 μm nor more than 0.2 μm.
A drive assist device for assisting a drive when a subject vehicle changes lanes, comprising: a position measurement unit configured to measure a position of the subject vehicle; a detection unit provided at the subject vehicle and configured to detect a surrounding situation of the subject vehicle; a database configured to store map information; and a setting unit configured to set a lane change location and a reference point on a travel route of the subject vehicle on a basis of the position of the subject vehicle and the map information, the lane change location being a location at which the subject vehicle should change lanes, the reference point being located ahead of the lane change location in a travel direction of the subject vehicle, the setting unit setting, on a basis of a detection range of the detection unit and a position of the reference point, a point at which the subject vehicle should complete changing lanes, as a lane change completion point, characterized in that the setting unit sets the lane change completion point at a position separate from the reference point at least by a length of the detection range in a direction opposite to the travel direction. a position measurement unit configured to measure a position of the subject vehicle; a detection unit provided at the subject vehicle and configured to detect a surrounding situation of the subject vehicle; a database configured to store map information; and a setting unit configured to set a lane change location and a reference point on a travel route of the subject vehicle on a basis of the position of the subject vehicle and the map information, the lane change location being a location at which the subject vehicle should change lanes, the reference point being located ahead of the lane change location in a travel direction of the subject vehicle, the setting unit setting, on a basis of a detection range of the detection unit and a position of the reference point, a point at which the subject vehicle should complete changing lanes, as a lane change completion point, characterized in that the setting unit sets the lane change completion point at a position separate from the reference point at least by a length of the detection range in a direction opposite to the travel direction.
An electronic device comprising: a window (161a, 161b, 1600) having a first refractive index with respect to light; a light emitting module disposed in an area under the window (161a, 161b, 1600) and configured to radiate infrared light; a fingerprint sensor disposed under the window and configured to obtain a fingerprint of a user based on a user input on the window (161a, 161b, 1600) using scattered light of the infrared light; and a light change layer (312, 604) which is formed in the window (161a, 161b, 1600) configured to change a propagation direction of the infrared light radiated by the light emitting module such that the infrared light is totally reflected inside the window (161a, 161b, 1600) in correspondence with the first refractive index, wherein the light change layer (312, 604) consists of: an optical pattern formed in the window (161a, 1600) corresponding to the area in which the light emitting module is disposed; or an optical member disposed in a recess formed in the window corresponding to the area in which the light emitting module is disposed. a window (161a, 161b, 1600) having a first refractive index with respect to light; a light emitting module disposed in an area under the window (161a, 161b, 1600) and configured to radiate infrared light; a fingerprint sensor disposed under the window and configured to obtain a fingerprint of a user based on a user input on the window (161a, 161b, 1600) using scattered light of the infrared light; and a light change layer (312, 604) which is formed in the window (161a, 161b, 1600) configured to change a propagation direction of the infrared light radiated by the light emitting module such that the infrared light is totally reflected inside the window (161a, 161b, 1600) in correspondence with the first refractive index, wherein the light change layer (312, 604) consists of: an optical pattern formed in the window (161a, 1600) corresponding to the area in which the light emitting module is disposed; or an optical member disposed in a recess formed in the window corresponding to the area in which the light emitting module is disposed. an optical pattern formed in the window (161a, 1600) corresponding to the area in which the light emitting module is disposed; or an optical member disposed in a recess formed in the window corresponding to the area in which the light emitting module is disposed.
A tube fitting comprising: a first coupling member having at least a snap coupling wherein the snap coupling is a retaining ring groove and a retaining ring where the retaining ring is captured within the retaining ring groove; a second coupling member having a first quick-connect side with a mating snap coupling disposed at a first end of the second coupling member wherein the mating snap coupling is a groove, and at least one elastomeric seal disposed on the second coupling member; and a sleeve member configured to interface with the first coupling member and the at least one elastomeric seal; and wherein the sleeve member is disposed between and retained by the first coupling member and the second coupling member and the snap coupling and mating snap coupling effect coupling of the first coupling member and the second coupling member, and wherein the retaining ring is configured to radially expand within the retaining ring groove of the snap coupling so that the first coupling member is slidable over the second coupling member and subsequently to radially contract, thereby allowing the tube fitting, in an assembled state, withstanding fluidic system pressures, burst and blow off loads. a first coupling member having at least a snap coupling wherein the snap coupling is a retaining ring groove and a retaining ring where the retaining ring is captured within the retaining ring groove; a second coupling member having a first quick-connect side with a mating snap coupling disposed at a first end of the second coupling member wherein the mating snap coupling is a groove, and at least one elastomeric seal disposed on the second coupling member; and a sleeve member configured to interface with the first coupling member and the at least one elastomeric seal; and a first quick-connect side with a mating snap coupling disposed at a first end of the second coupling member wherein the mating snap coupling is a groove, and at least one elastomeric seal disposed on the second coupling member; and wherein the sleeve member is disposed between and retained by the first coupling member and the second coupling member and the snap coupling and mating snap coupling effect coupling of the first coupling member and the second coupling member, and wherein the retaining ring is configured to radially expand within the retaining ring groove of the snap coupling so that the first coupling member is slidable over the second coupling member and subsequently to radially contract, thereby allowing the tube fitting, in an assembled state, withstanding fluidic system pressures, burst and blow off loads.
Sensor apparatus comprising: - at least one sensor; - a housing for the at least one sensor; - at least one solar cell for supplying energy to the at least one sensor, wherein the at least one solar cell is mounted on an external wall of the housing; and - a cover, which covers a photovoltaically active side of the at least one solar cell, wherein the cover comprises a translucent material, wherein particles having light-scattering properties are embedded in the translucent material, and wherein the translucent material comprises a fluorescent material through which incident photons of the incoming light are converted into wavelengths in which the quantum efficiency of the solar cell is greater than in the case of the wavelengths of the original incoming light. - at least one sensor; - a housing for the at least one sensor; - at least one solar cell for supplying energy to the at least one sensor, wherein the at least one solar cell is mounted on an external wall of the housing; and - a cover, which covers a photovoltaically active side of the at least one solar cell, wherein the cover comprises a translucent material, wherein particles having light-scattering properties are embedded in the translucent material, and wherein the translucent material comprises a fluorescent material through which incident photons of the incoming light are converted into wavelengths in which the quantum efficiency of the solar cell is greater than in the case of the wavelengths of the original incoming light.
A method of measuring the rate of reaction between a target molecule and a ligand candidate comprising the steps of: a) providing a target molecule comprising a binding site of interest and a thiol group within or near the binding site of interest, wherein the thiol group is near the binding site of interest when it is close enough to the binding site of interest to allow the formation of a covalent bond between the thiol group and a functional group on the ligand candidate, when the ligand candidate binds to the binding site of interest; b) contacting the target molecule with a ligand candidate in a reaction mixture, wherein the ligand candidate comprises a functional group which is capable of forming an irreversible covalent bond with said thiol group; c) forming an irreversible covalent bond between the thiol group of the target molecule and the functional group of the ligand candidate, thereby forming a target molecule-ligand conjugate; d) contacting the reaction mixture or an aliquot thereof with a thiol quantification reagent at a defined time point during the reaction, wherein the thiol quantification reagent is capable of bonding to free thiol groups to form a quantification conjugate which provides the reaction mixture or aliquot thereof with a biophysical property assessable by a biophysical method; e) measuring the biophysical property of the reaction mixture or aliquot thereof; and f) calculating the rate of reaction between the target molecule and the ligand candidate. a) providing a target molecule comprising a binding site of interest and a thiol group within or near the binding site of interest, wherein the thiol group is near the binding site of interest when it is close enough to the binding site of interest to allow the formation of a covalent bond between the thiol group and a functional group on the ligand candidate, when the ligand candidate binds to the binding site of interest; b) contacting the target molecule with a ligand candidate in a reaction mixture, wherein the ligand candidate comprises a functional group which is capable of forming an irreversible covalent bond with said thiol group; c) forming an irreversible covalent bond between the thiol group of the target molecule and the functional group of the ligand candidate, thereby forming a target molecule-ligand conjugate; d) contacting the reaction mixture or an aliquot thereof with a thiol quantification reagent at a defined time point during the reaction, wherein the thiol quantification reagent is capable of bonding to free thiol groups to form a quantification conjugate which provides the reaction mixture or aliquot thereof with a biophysical property assessable by a biophysical method; e) measuring the biophysical property of the reaction mixture or aliquot thereof; and f) calculating the rate of reaction between the target molecule and the ligand candidate.
A bioabsorbable suture thread comprising: a core thread made of a bioabsorbable lower-melting component; and a plurality of winding threads made of a bioabsorbable higher-melting component, the winding threads being wound around the core thread, wherein the bioabsorbable suture thread has a structure in which the core thread molten by heat treatment is bonded to the winding threads wherein the number of the winding threads wound around the core thread is 3 or more, wherein the bioabsorbable lower-melting component constituting the core thread has a melting point of 50 to 200°C, and the bioabsorbable higher-melting component constituting the winding threads has a melting point of 180 to 290°C, wherein the bioabsorbable lower-melting component constituting the core thread is at least one selected from the group consisting of ε-polycaprolactone, a copolymer of ε-polycaprolactone and glycolic acid, and a copolymer of ε-polycaprolactone and lactic acid, wherein the bioabsorbable higher-melting component constituting the winding threads is polyglycolic acid and/or a copolymer of glycolic acid and lactic acid.
A method of removing moisture in a sealed system comprising a compressor comprising: a. introducing a fluid comprising a refrigerant and a lubricant oil into the sealed system comprising the compressor; and b. contacting the fluid with a dehydration device located inside the compressor at a location that facilitates contact with the fluid to remove a portion of moisture from the fluid within the sealed system, wherein the dehydration device comprises a composite comprising a sorbent material in a polymer matrix, wherein the composite has a first water affinity and the fluid has a second water affinity, wherein the first water affinity is greater than the second water affinity, characterized in that the composite is shaped as an integral component of the compressor. a. introducing a fluid comprising a refrigerant and a lubricant oil into the sealed system comprising the compressor; and b. contacting the fluid with a dehydration device located inside the compressor at a location that facilitates contact with the fluid to remove a portion of moisture from the fluid within the sealed system,
A method for mitigating memory imprinting in volatile configuration memory, CM, of a field programmable gate array, FPGA, device, said method comprising: providing an FPGA device with a CM input inversion plane between a CM controller and a layer of CM cells, a CM output inversion plane between the layer of CM cells and a programmable function block layer, and a CM inversion control module in communication with the CM input and output inversion planes; determining, by the CM inversion control module at system power-up, whether to select a normal mode or an inversion mode for a current power cycle, wherein the normal mode is a mode configured to allow data flowing into and out of the layer of CM cells to flow without inversion; inverting (614, 616), by the CM input and output inversion planes when operating in the inversion mode, data flowing into and out of the layer of CM cells, where inverting includes swapping values of logical ones and zeroes; tracking, by the CM inversion control module, cumulative system times operating in the normal mode and the inversion mode; and writing the cumulative system times to a CM mode non-volatile memory module, at system power-down, for use in determining which mode to select at a next system power-up, wherein determining whether to operate a current power cycle in a normal mode or an inversion mode includes reading the cumulative system times from the CM mode non-volatile memory module and setting the current power cycle to a mode with less cumulative time. providing an FPGA device with a CM input inversion plane between a CM controller and a layer of CM cells, a CM output inversion plane between the layer of CM cells and a programmable function block layer, and a CM inversion control module in communication with the CM input and output inversion planes; determining, by the CM inversion control module at system power-up, whether to select a normal mode or an inversion mode for a current power cycle, wherein the normal mode is a mode configured to allow data flowing into and out of the layer of CM cells to flow without inversion; inverting (614, 616), by the CM input and output inversion planes when operating in the inversion mode, data flowing into and out of the layer of CM cells, where inverting includes swapping values of logical ones and zeroes; tracking, by the CM inversion control module, cumulative system times operating in the normal mode and the inversion mode; and writing the cumulative system times to a CM mode non-volatile memory module, at system power-down, for use in determining which mode to select at a next system power-up, wherein determining whether to operate a current power cycle in a normal mode or an inversion mode includes reading the cumulative system times from the CM mode non-volatile memory module and setting the current power cycle to a mode with less cumulative time.