Rotary tablet press machine comprising: - a compression turret rotating with a rotation direction about a rotation axis and including a die table, provided along a circumferential portion thereof with a plurality of dies, a plurality of lower punches and a corresponding plurality of upper punches associated in pairs with respective dies; - a dosing station comprising filling means for filling with a product dosing cavities that are formed by said dies closed at the bottom by said lower punches and have a settled filling depth (L1, L2, L3, L4) and - cam means cooperating with said lower punches for moving the lower punches inside the respective dies and obtaining said settled filling depth (L1, L2, L3, L4), wherein said cam means comprise a first filling cam provided with a first channel and a second filling cam provided with a second channel, said first channel and said second channel being configured and mutually arranged to guide follower ends of said lower punches along a filling channel; characterized in that it comprises: - a first adjustment element supporting said first filling cam and a second adjustment element supporting said second filling cam, which is mounted on said second adjustment element slidably along an arc of circumference about said rotation axis, said second adjustment element being configured to be moved with respect to said first adjustment element along a first direction parallel to said rotation axis; - first driving means configured to move with respect to said compression turret and along said first direction simultaneously said first adjustment element supporting said first filling cam and said second adjustment element slidably supporting said second filling cam; and - second driving means configured to move, with respect to said first filling cam, said second adjustment element and said second filling cam in a coordinated manner respectively along the first direction and along the second adjustment element and about said rotation axis; wherein said first filling cam and said second filling cam are configured to be positioned with respect to each other by said first driving means and said second driving means so that said first channel and said second channel form said filling channel having a length and a profile such as to carry out the required displacement of the lower punches to obtain said settled filling depth (L1, L2, L3, L4) and wherein said first channel at an end thereof for entry of the lower punch has an inlet height bigger than an operating height (h) of said follower end of the lower punch. - a compression turret rotating with a rotation direction about a rotation axis and including a die table, provided along a circumferential portion thereof with a plurality of dies, a plurality of lower punches and a corresponding plurality of upper punches associated in pairs with respective dies; - a dosing station comprising filling means for filling with a product dosing cavities that are formed by said dies closed at the bottom by said lower punches and have a settled filling depth (L1, L2, L3, L4) and - cam means cooperating with said lower punches for moving the lower punches inside the respective dies and obtaining said settled filling depth (L1, L2, L3, L4), wherein said cam means comprise a first filling cam provided with a first channel and a second filling cam provided with a second channel, said first channel and said second channel being configured and mutually arranged to guide follower ends of said lower punches along a filling channel; - a first adjustment element supporting said first filling cam and a second adjustment element supporting said second filling cam, which is mounted on said second adjustment element slidably along an arc of circumference about said rotation axis, said second adjustment element being configured to be moved with respect to said first adjustment element along a first direction parallel to said rotation axis; - first driving means configured to move with respect to said compression turret and along said first direction simultaneously said first adjustment element supporting said first filling cam and said second adjustment element slidably supporting said second filling cam; and - second driving means configured to move, with respect to said first filling cam, said second adjustment element and said second filling cam in a coordinated manner respectively along the first direction and along the second adjustment element and about said rotation axis; wherein said first filling cam and said second filling cam are configured to be positioned with respect to each other by said first driving means and said second driving means so that said first channel and said second channel form said filling channel having a length and a profile such as to carry out the required displacement of the lower punches to obtain said settled filling depth (L1, L2, L3, L4) and wherein said first channel at an end thereof for entry of the lower punch has an inlet height bigger than an operating height (h) of said follower end of the lower punch.