mhurhangee/ep-ind-claims huggingface dataset:
An extended-release capsule dosage form of metoprolol succinate in the form of coated discrete units, comprising: a) inert cores; b) a drug layer over the inert cores comprising metoprolol succinate; and c) an extended release layer over the drug layer coated cores, wherein the extended release layer comprises water-soluble polymer, selected from the group consisting of hydroxypropyl methyl cellulose, hydroxyethyl cellulose, polyethylene glycol, poly (ethylene oxide), hydroxypropyl cellulose, carboxymethyl cellulose, xanthan gum, starch, and mixtures thereof; and water-insoluble polymer, selected from the group consisting of cellulose ethers, cellulose esters, polymethacrylic acid esters copolymers, aminoalkyl methacrylate copolymers, copolymers of polyvinyl acetate and polyvinyl pyrrolidone, and mixtures thereof; and is present in an amount of 5% to 30% based on the weight of the drug layer coated cores, wherein the metoprolol succinate is present in an amount of 30% to 70% by the total weight of the dosage form and is bioequivalent to the marketed Toprol-XL ® tablet and wherein the extended-release capsule dosage form is in the form of a sprinkle capsule and the coated discrete units have a particle size from 0.2 mm to 2.5 mm. a) inert cores; b) a drug layer over the inert cores comprising metoprolol succinate; and c) an extended release layer over the drug layer coated cores, wherein the extended release layer comprises water-soluble polymer, selected from the group consisting of hydroxypropyl methyl cellulose, hydroxyethyl cellulose, polyethylene glycol, poly (ethylene oxide), hydroxypropyl cellulose, carboxymethyl cellulose, xanthan gum, starch, and mixtures thereof; and water-insoluble polymer, selected from the group consisting of cellulose ethers, cellulose esters, polymethacrylic acid esters copolymers, aminoalkyl methacrylate copolymers, copolymers of polyvinyl acetate and polyvinyl pyrrolidone, and mixtures thereof; and is present in an amount of 5% to 30% based on the weight of the drug layer coated cores, wherein the metoprolol succinate is present in an amount of 30% to 70% by the total weight of the dosage form and is bioequivalent to the marketed Toprol-XL ® tablet and wherein the extended-release capsule dosage form is in the form of a sprinkle capsule and the coated discrete units have a particle size from 0.2 mm to 2.5 mm.
Apparatus for inspecting a pharmaceutical cylindrical container made of glass or of a polymer, wherein the apparatus comprises a support device, a light receiving unit and a light emitting unit, wherein the support device supports the pharmaceutical cylindrical container on its lateral surface, such that the pharmaceutical cylindrical container is rotatable around its longitudinal axis, wherein the light receiving unit comprises a main camera for acquiring an image of the pharmaceutical cylindrical container, and whereby the light emitting unit comprises with regard to the main camera a bright field light source, a radial dark field light source, and an axial dark field light source. wherein the support device supports the pharmaceutical cylindrical container on its lateral surface, such that the pharmaceutical cylindrical container is rotatable around its longitudinal axis, wherein the light receiving unit comprises a main camera for acquiring an image of the pharmaceutical cylindrical container, and whereby the light emitting unit comprises with regard to the main camera a bright field light source, a radial dark field light source, and an axial dark field light source.
A support device for an ankle, comprising: a main body having a medial portion and a lateral portion disposed about the ankle, and an interior surface, wherein said main body further comprises a flexible front portion (104, 130) and a flexible rear portion (102, 128) disposed opposite of one another, and wherein edges of the front portion (104, 130) and the rear portion (102, 128) are coupled to edges of the medial portion and the lateral portion; wherein the flexible front portion, the flexible rear portion, the medial portion and the lateral portion are arranged in a patchwork arrangement and wherein the flexible front portion (104, 130) and the flexible rear portion (102, 128) comprise a more flexible material than the medial portion and the lateral portion; at least one of a medial support member disposed in a cavity in the medial portion of said main body and a lateral support member disposed in a cavity in the lateral portion of said main body; a strap disposed on a proximal portion of said main body, said strap having fastening means adapted to create a first level of pressure in the front of the lower leg immediately proximal to the ankle and a second level of pressure in the rear of the lower leg immediately proximal to the ankle; and one or more proprioceptive members disposed on the interior surface of said main body. a main body having a medial portion and a lateral portion disposed about the ankle, and an interior surface, wherein said main body further comprises a flexible front portion (104, 130) and a flexible rear portion (102, 128) disposed opposite of one another, and wherein edges of the front portion (104, 130) and the rear portion (102, 128) are coupled to edges of the medial portion and the lateral portion; wherein the flexible front portion, the flexible rear portion, the medial portion and the lateral portion are arranged in a patchwork arrangement and wherein the flexible front portion (104, 130) and the flexible rear portion (102, 128) comprise a more flexible material than the medial portion and the lateral portion; at least one of a medial support member disposed in a cavity in the medial portion of said main body and a lateral support member disposed in a cavity in the lateral portion of said main body; a strap disposed on a proximal portion of said main body, said strap having fastening means adapted to create a first level of pressure in the front of the lower leg immediately proximal to the ankle and a second level of pressure in the rear of the lower leg immediately proximal to the ankle; and one or more proprioceptive members disposed on the interior surface of said main body.
A variable displacement assembly for a fluid device, the variable displacement assembly comprising: a rotor having a rotation axis about which the rotor selectively rotates and defining a plurality of bores; a plurality of reciprocating members (44; 200, 300) in engagement with the plurality of bores of the rotor; a ring assembly defining a cam surface in engagement with the reciprocating members (44; 200, 300), the ring assembly having a first ring and an axially adjacent second ring, at least one of the first and second rings being adapted for selective movement relative to the other between a neutral position and a displaced position, the first ring having a first ring portion defining a bore having an inner surface, the second ring having a second ring portion defining a bore having an inner surface, characterized in that a first circumferential portion of the inner surface of the first ring portion and a second circumferential portion of the inner surface of the second ring portion define the cam surface in the displaced position; and in that the first ring portion has at least one displacement ring, and the second ring portion has at least two displacement rings, wherein the at least one displacement ring of the first ring portion and the two displacement rings of the second ring portion are alternatingly disposed in the ring assembly. a rotor having a rotation axis about which the rotor selectively rotates and defining a plurality of bores; a plurality of reciprocating members (44; 200, 300) in engagement with the plurality of bores of the rotor; a ring assembly defining a cam surface in engagement with the reciprocating members (44; 200, 300), the ring assembly having a first ring and an axially adjacent second ring, at least one of the first and second rings being adapted for selective movement relative to the other between a neutral position and a displaced position, the first ring having a first ring portion defining a bore having an inner surface, the second ring having a second ring portion defining a bore having an inner surface, characterized in that a first circumferential portion of the inner surface of the first ring portion and a second circumferential portion of the inner surface of the second ring portion define the cam surface in the displaced position; and in that the first ring portion has at least one displacement ring, and the second ring portion has at least two displacement rings, wherein the at least one displacement ring of the first ring portion and the two displacement rings of the second ring portion are alternatingly disposed in the ring assembly.
Method for detecting a blocked condensate drain of a heater, comprising at least the following steps: a) detecting an operating parameter of the heater which allows a voltage amplitude of an ionization electrode of a flame detection system to be inferred, b) comparing the operating parameter detected in step a) with a limit value, c) recognizing a blocked condensate drain from the comparison according to step b), characterized in that the operating parameter detected in step a) is a manipulated variable of a control circuit for keeping the voltage amplitude of an AC voltage signal of the ionization electrode of the flame detection system constant. a) detecting an operating parameter of the heater which allows a voltage amplitude of an ionization electrode of a flame detection system to be inferred, b) comparing the operating parameter detected in step a) with a limit value, c) recognizing a blocked condensate drain from the comparison according to step b),
A multilayer silo bag comprising: a tube comprising at least two layers, the tube having a first open end, a second open end, and a first region disposed between the first and second end and a second region disposed between the first and second end, wherein each of the at least two layers comprises an ethylene/alpha-olefin interpolymer having a density of 0.90 g/cc to 0.965 g/cc when measured according to ASTM D792 and a melt index (I 2) of 0.1 to 6.0 g/10 minutes when measured according to ASTM D1238, a low density ethylene-based polymer having a density of 0.917 g/cc to 0.935 g/cc and melt index (I 2) of 0.1 to 2.0 g/10 minutes, or combinations thereof; wherein the first region has a thickness 10% to 40% greater than a thickness of the second region; wherein the first region has a surface area that is at least 65% of an overall surface area of the multilayer silo bag; and wherein the tube has an overall thickness (average thickness of the silo bag) of 50 micrometers (μm) to 350 μm. a tube comprising at least two layers, the tube having a first open end, a second open end, and a first region disposed between the first and second end and a second region disposed between the first and second end, wherein each of the at least two layers comprises an ethylene/alpha-olefin interpolymer having a density of 0.90 g/cc to 0.965 g/cc when measured according to ASTM D792 and a melt index (I 2) of 0.1 to 6.0 g/10 minutes when measured according to ASTM D1238, a low density ethylene-based polymer having a density of 0.917 g/cc to 0.935 g/cc and melt index (I 2) of 0.1 to 2.0 g/10 minutes, or combinations thereof; wherein the first region has a thickness 10% to 40% greater than a thickness of the second region; wherein the first region has a surface area that is at least 65% of an overall surface area of the multilayer silo bag; and wherein the tube has an overall thickness (average thickness of the silo bag) of 50 micrometers (μm) to 350 μm.
A method for assembling a plurality of harvested micro tissue grafts, the method comprising: a) arranging the plurality of micro tissue grafts in a desired orientation; and b) forming a tissue construct containing the plurality of micro tissue grafts arranged in the desired orientation, the tissue construct being a solid, three-dimensional construct that maintains the plurality of micro tissue grafts therein in the desired orientation for application of the tissue construct to a recipient site, wherein the tissue construct includes the plurality of micro tissue grafts arranged in the desired orientation within a supportive material, and characterised in that step b) includes rolling a strip of the supportive material and attaching the plurality of micro tissue grafts attached to the strip at spaced-apart intervals during rolling. a) arranging the plurality of micro tissue grafts in a desired orientation; and b) forming a tissue construct containing the plurality of micro tissue grafts arranged in the desired orientation, the tissue construct being a solid, three-dimensional construct that maintains the plurality of micro tissue grafts therein in the desired orientation for application of the tissue construct to a recipient site, wherein the tissue construct includes the plurality of micro tissue grafts arranged in the desired orientation within a supportive material, and characterised in that step b) includes rolling a strip of the supportive material and attaching the plurality of micro tissue grafts attached to the strip at spaced-apart intervals during rolling. wherein the tissue construct includes the plurality of micro tissue grafts arranged in the desired orientation within a supportive material, and characterised in that step b) includes rolling a strip of the supportive material and attaching the plurality of micro tissue grafts attached to the strip at spaced-apart intervals during rolling.
A receiving device, comprising: at least two selecting modules, a fast optical switch connecting to each selecting module, an output module connecting to all fast optical switches, and a receiver connecting to the output module, wherein the selecting module is configured to receive a multiwavelength optical signal, filter a first optical signal of a set time segment from the multiwavelength optical signal, and send the first optical signal to the fast optical switch; the fast optical switch is configured to select a second optical signal from the first optical signal filtered by the selecting module, and send the second optical signal to the output module; the output module is configured to combine the second optical signals separately selected by all the fast optical switches into one optical burst signal, and send the optical burst signal to the receiver; and the receiver is configured to perform optical-to-electrical conversion on the optical burst signal to obtain an electrical signal, extract service data from the electrical signal, and output the service data, wherein the first optical signals separately output by the at least two selecting modules partly overlap in the time; and the second optical signals output by at least two fast optical switches do not overlap in the time. at least two selecting modules, a fast optical switch connecting to each selecting module, an output module connecting to all fast optical switches, and a receiver connecting to the output module, wherein the selecting module is configured to receive a multiwavelength optical signal, filter a first optical signal of a set time segment from the multiwavelength optical signal, and send the first optical signal to the fast optical switch; the fast optical switch is configured to select a second optical signal from the first optical signal filtered by the selecting module, and send the second optical signal to the output module; the output module is configured to combine the second optical signals separately selected by all the fast optical switches into one optical burst signal, and send the optical burst signal to the receiver; and the receiver is configured to perform optical-to-electrical conversion on the optical burst signal to obtain an electrical signal, extract service data from the electrical signal, and output the service data, wherein the first optical signals separately output by the at least two selecting modules partly overlap in the time; and the second optical signals output by at least two fast optical switches do not overlap in the time.
A method for forming an Atomic Force Microscopy probe configuration, comprising a cantilever and a planar tip attached to a sidewall of the cantilever and extending along a longitudinal direction (x) of the cantilever, the method comprising: - providing a flat substrate, - forming a planar diamond layer on this flat substrate, - forming the planar tip by patterning this planar diamond layer in an essentially two-dimensional geometry having at least one corner, whereby diamond nano-crystallites protrude from the diamond surface of the planar tip, - forming a cantilever portion and a holder chip area by a subsequent deposition step of a metallic seedlayer for plating the cantilever and the holder chip area, lithographic patterning thereof to outline the cantilever and holder chip area and plating the seedlayer exposed at the location of the cantilever and holder chip area, in such a way that the planar tip is attached by a sidewall thereof to the cantilever portion at a location remote from the corner of the planar tip, and; releasing the planar tip, the attached cantilever and the holder chip area from the flat substrate. - providing a flat substrate, - forming a planar diamond layer on this flat substrate, - forming the planar tip by patterning this planar diamond layer in an essentially two-dimensional geometry having at least one corner, whereby diamond nano-crystallites protrude from the diamond surface of the planar tip, - forming a cantilever portion and a holder chip area by a subsequent deposition step of a metallic seedlayer for plating the cantilever and the holder chip area, lithographic patterning thereof to outline the cantilever and holder chip area and plating the seedlayer exposed at the location of the cantilever and holder chip area, in such a way that the planar tip is attached by a sidewall thereof to the cantilever portion at a location remote from the corner of the planar tip, and; releasing the planar tip, the attached cantilever and the holder chip area from the flat substrate.
A method for handling a sample tube containing a biological sample, a tube label (210, 306) being attached to the sample tube, the tube label carrying tube data, the tube data comprising at least geometric tube data being descriptive of at least one geometric property of the sample tube, the method comprising: - reading at least the geometric tube data from the tube label (210, 306) by a reader device, - transmitting at least the geometric tube data from the reader device to a processing device; - controlling the processing device for handling the sample tube in accordance with the at least one geometric property described by the read geometric data, the tube label comprising: - an optically readable pattern, such as a barcode, in particular a two-dimensional bar code; or - a sender for sending the tube data via an antenna, the antenna being attached to the sample tube; the method being characterized in that: - the processing device is one of: a capper, a decapper, an aliquoter, a centrifuge or a gripper for gripping the sample tube or cap of the sample tube; - and in that the method further comprises deriving the tube type from the geometric data read from the tube label. - reading at least the geometric tube data from the tube label (210, 306) by a reader device, - transmitting at least the geometric tube data from the reader device to a processing device; - controlling the processing device for handling the sample tube in accordance with the at least one geometric property described by the read geometric data, - an optically readable pattern, such as a barcode, in particular a two-dimensional bar code; or - a sender for sending the tube data via an antenna, the antenna being attached to the sample tube; - the processing device is one of: a capper, a decapper, an aliquoter, a centrifuge or a gripper for gripping the sample tube or cap of the sample tube; - and in that the method further comprises deriving the tube type from the geometric data read from the tube label.
A bubble trap for a fuel tank for storing liquids for operating the power units of spacecraft, having a propellant gas used as flow medium and also having an arrangement for separating the propellant gas from the liquid fuel, in which a separation of the propellant gas from the liquid is brought about in a collection chamber by means of sieves and utilizing the surface tension, a series of guide plates, arranged essentially radially in the region of the outer wall of the collection chamber, being provided in a rotationally symmetrical collection chamber, characterized in that a gas separator, tapering in a conical manner in the direction of an outlet pipe and provided with through holes, and sieves (17, 18) are provided in the vicinity of the outlet region of the collection container.
A user equipment, UE, comprising: a sending module, configured to send, to a mobility management entity, MME, a request message for requesting to perform circuit switched fallback, CSFB; a receiving module, configured to receive a switch command sent by an evolved base station eNodeB, wherein the switch command instructs the UE to switch from a packet switched, PS, domain to a circuit switched, CS, domain; a processing module, configured to hold a default CS call of the UE after the UE switches to the CS domain according to the switch command, wherein the default CS call is generated by the UE according to the switch command; and a call module, configured to, by using a mobile switching center, MSC, initiate a CS call or receive a CS call. a sending module, configured to send, to a mobility management entity, MME, a request message for requesting to perform circuit switched fallback, CSFB; a receiving module, configured to receive a switch command sent by an evolved base station eNodeB, wherein the switch command instructs the UE to switch from a packet switched, PS, domain to a circuit switched, CS, domain; a processing module, configured to hold a default CS call of the UE after the UE switches to the CS domain according to the switch command, wherein the default CS call is generated by the UE according to the switch command; and a call module, configured to, by using a mobile switching center, MSC, initiate a CS call or receive a CS call.
A polyester resin composition, comprising: a polysiloxane-mixed polyester resin comprising a polyester compound and an amino group-containing polysiloxane compound mixed; a phosphorus-containing flame retardant; a metal hydrate; and a fluorine-containing polymer, wherein the metal hydrate is at least one selected from aluminum hydroxide, magnesium hydroxide, dawsonite, calcium aluminate, hydrated gypsum, calcium hydroxide, zinc borate, barium metaborate, borax, kaolin clay and calcium carbonate, wherein a content of the polyester compound is in the range of 30 to 65% by mass with respect to the polyester resin composition; a content of the amino group-containing polysiloxane compound is in the range of 1.5 to 10% by mass with respect to the polyester resin composition; a content of the phosphorus-containing flame retardant is in the range of 1 to 20% by mass with respect to the polyester resin composition; a content of the metal hydrate is in the range of 30 to 60% by mass with respect to the polyester resin composition; and a content of the fluorine-containing polymer is in the range of 0.1 to 5% by mass with respect to the polyester resin composition, wherein the polyester compound comprises a polylactic acid compound and an aliphatic polyester resin.
A dry powder formulation for inhalation comprising: - vilanterol or a pharmaceutically acceptable salt thereof, - coarse carrier, - fine carrier, and - magnesium stearate, characterized in that the ratio of the volume median diameter of the fine carrier to the volume median diameter of the magnesium stearate is 1:1 and the volume median diameter of the magnesium stearate is between 1μm and 120 μm. - vilanterol or a pharmaceutically acceptable salt thereof, - coarse carrier, - fine carrier, and - magnesium stearate,