A compound of Formula II: wherein R 1 is: H; C 1 -C 6 alkyl; benzyl; or -C(=O)R 8; R 2 is: H; or C 1 -C 6 alkyl; alternatively R 1 and R 2 may be taken together to form =CR 11 N(R 12)R 13; R 3 is: -C(=O)R 8; or -C(=S)R 8; R 5 is independently halogen, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, halothio, amino, C 1 -C 6 alkylamino, C 2 -C 6 dialkylamino, C 2 -C 6 alkoxycarbonyl, C 2 -C 6 alkylcarbonyl, nitro, hydroxyl, or cyano; R 8 is H, ethyl, propyl, butyl, isopropyl, isobutyl, tertiary butyl, pentyl, hexyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, C 2 -C 6 alkenyl, C 3 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyalkyl, phenyl or benzyl wherein each of the phenyl or the benzyl may be optionally substituted with 1-3 R 5, or with a 5- or 6-membered saturated or unsaturated ring system, or with a 5-6 fused ring system, or with a 6-6 fused ring system each containing 1-3 heteroatoms wherein each ring may be optionally substituted with 1-3 R 5, biphenyl or naphthyl optionally substituted with 1-3 R 5; R 11 is H or C 1 -C 4 alkyl; R 12 is H, cyano, hydroxyl, C 1 -C 4 alkyl, C 1 -C 6 alkoxy, C 2 -C 6 alkylcarbonyl, phenyl or benzyl wherein each of the phenyl or the benzyl may be optionally substituted with 1-3 R 5; alternatively R 11 and R 12 may be taken together to form a 5- or 6-membered saturated or unsaturated ring containing 1-3 heteroatoms wherein each ring may be optionally substituted with 1-3 R 5; R 13 is H, C 1 -C 4 alkyl, C 1 -C 6 alkoxy, C 2 -C 6 alkylcarbonyl, phenyl or benzyl wherein each of the phenyl or the benzyl may be optionally substituted with 1-3 R 5; and alternatively R 12 and R 13 may be taken together to form a 5- or 6-membered saturated or unsaturated ring containing 1-3 heteroatoms wherein each ring may be optionally substituted with 1-3 R 5, or an optical isomer, a salt or a hydrate thereof, wherein the alkyl is a branched, unbranched, or cyclic carbon chain. wherein R 1 is: H; C 1 -C 6 alkyl; benzyl; or -C(=O)R 8; H; C 1 -C 6 alkyl; benzyl; or -C(=O)R 8; R 2 is: H; or C 1 -C 6 alkyl; H; or C 1 -C 6 alkyl; alternatively R 1 and R 2 may be taken together to form =CR 11 N(R 12)R 13; R 3 is: -C(=O)R 8; or -C(=S)R 8; -C(=O)R 8; or -C(=S)R 8; R 5 is independently halogen, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, halothio, amino, C 1 -C 6 alkylamino, C 2 -C 6 dialkylamino, C 2 -C 6 alkoxycarbonyl, C 2 -C 6 alkylcarbonyl, nitro, hydroxyl, or cyano; R 8 is H, ethyl, propyl, butyl, isopropyl, isobutyl, tertiary butyl, pentyl, hexyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, C 2 -C 6 alkenyl, C 3 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyalkyl, phenyl or benzyl wherein each of the phenyl or the benzyl may be optionally substituted with 1-3 R 5, or with a 5- or 6-membered saturated or unsaturated ring system, or with a 5-6 fused ring system, or with a 6-6 fused ring system each containing 1-3 heteroatoms wherein each ring may be optionally substituted with 1-3 R 5, biphenyl or naphthyl optionally substituted with 1-3 R 5; R 11 is H or C 1 -C 4 alkyl; R 12 is H, cyano, hydroxyl, C 1 -C 4 alkyl, C 1 -C 6 alkoxy, C 2 -C 6 alkylcarbonyl, phenyl or benzyl wherein each of the phenyl or the benzyl may be optionally substituted with 1-3 R 5; alternatively R 11 and R 12 may be taken together to form a 5- or 6-membered saturated or unsaturated ring containing 1-3 heteroatoms wherein each ring may be optionally substituted with 1-3 R 5; R 13 is H, C 1 -C 4 alkyl, C 1 -C 6 alkoxy, C 2 -C 6 alkylcarbonyl, phenyl or benzyl wherein each of the phenyl or the benzyl may be optionally substituted with 1-3 R 5; and alternatively R 12 and R 13 may be taken together to form a 5- or 6-membered saturated or unsaturated ring containing 1-3 heteroatoms wherein each ring may be optionally substituted with 1-3 R 5, or an optical isomer, a salt or a hydrate thereof, wherein the alkyl is a branched, unbranched, or cyclic carbon chain.