A tissue specimen collection system comprising: a collection device adapted to be removably and serially engaged between a suction tube and a collection tube, the collection device being configured to be separable into a first segment comprising a distal end operably engaged with the collection tube and and a second segment comprising a proximal end operably engaged with the suction tube, the collection device defining a bore extending there through in coaxial relation with the suction tube and the collection tube, the bore being configured to allow fluid communication there between; a screen disposed within the bore of the collection device and positioned in the second segment of the collection device, the screen being configured to retain a tissue specimen drawn through the collection device by and towards the suction tube, the screen defining a plurality of apertures for allowing fluid communication between the collection tube and the suction tube; and said screen being positioned in the second segment of the collection device such that any fluid accompanying the tissue specimen passing through the collection tube and the first segment of the collection device is separated, and drawn through the screen and into the suction tube, while the tissue specimen is retained by the screen within the bore of the second segment of the collection device, and such that the retained tissue specimen is accessible for retrieval when the first segment is separated from the second segment, wherein the distal end of the collection device is configured to engage one end of the collection tube or suction tube and the proximal end of the collection device is configured to engage the other end of the collection tube or suction tube, such that the collection tube or suction tube may form a substantially continuous and closed fluid circuit with the bore defined in the collection device. a collection device adapted to be removably and serially engaged between a suction tube and a collection tube, the collection device being configured to be separable into a first segment comprising a distal end operably engaged with the collection tube and and a second segment comprising a proximal end operably engaged with the suction tube, the collection device defining a bore extending there through in coaxial relation with the suction tube and the collection tube, the bore being configured to allow fluid communication there between; a screen disposed within the bore of the collection device and positioned in the second segment of the collection device, the screen being configured to retain a tissue specimen drawn through the collection device by and towards the suction tube, the screen defining a plurality of apertures for allowing fluid communication between the collection tube and the suction tube; and said screen being positioned in the second segment of the collection device such that any fluid accompanying the tissue specimen passing through the collection tube and the first segment of the collection device is separated, and drawn through the screen and into the suction tube, while the tissue specimen is retained by the screen within the bore of the second segment of the collection device, and such that the retained tissue specimen is accessible for retrieval when the first segment is separated from the second segment, wherein the distal end of the collection device is configured to engage one end of the collection tube or suction tube and the proximal end of the collection device is configured to engage the other end of the collection tube or suction tube, such that the collection tube or suction tube may form a substantially continuous and closed fluid circuit with the bore defined in the collection device.