A compound having the following formula: or a stereoisomer or pharmaceutically-acceptable salt thereof, wherein: R 1 is C 1-3 alkyl optionally substituted by 0-7 R 1a; R 1a at each occurrence is independently hydrogen, deuterium, F, Cl, Br, CF 3 or CN; R 2 is C 1-6 alkyl or -(CH 2) r -3-14 membered carbocycle, each group substituted with 0-4 R 2a; R 2a at each occurrence is independently hydrogen, =O, halo, OCF 3, CN, NO 2, -(CH 2) r OR b, -(CH 2) r SR b, -(CH 2) r C R b, -(CH 2) r C OR b, -(CH 2) r OC R b, CH 2) r NR 11 R 11, -(CH 2) r C NR 11 R 11, -(CH 2) r NR b C R c, -(CH 2) r NR b C OR c, -NR b C NR 11 R 11, -S p NR 11 R 11, -NR b S p R c, -S p R c, C 1-6 alkyl substituted with 0-3 R a, C 1-6 haloalkyl, C 2-6 alkenyl substituted with 0-3 R a, C 2-6 alkynyl substituted with 0-3 R a, -(CH 2) r -3-14 membered carbocycle substituted with 0-1 R a or a -(CH 2) r -5-7 membered heterocycle comprising carbon atoms or 1-4 heteroatoms selected from N, O, and S p substituted with 0-2 R a; R 3 is R 3aa is S p R c, OR b, chloro, F, CN, NH 2, C NR 11 R 11, NR b SO p R c, NR b C R c, C 1-6 alkyl substituted with 0-3 R a or a 5- to 6-membered heteroaryl containing 1-3 heteroatoms selected from N, O, and S substituted with 0-3 R a; R 3ab, R 3ac, or R 3ad are independently hydrogen, Cl, F, Br, CN, OR b, C 1-6 alkyl substituted 0-3 R a; C NR 11 R 11, C R b, S p R c, or a 4-7 membered heterocycle containing1-3 heteroatoms selected from N, O, and S substituted with 0-3 R a; R a is OR b or halo; R b is hydrogen, C 1-6 alkyl substituted with 0-2 R d, a 5- to 7-membered heterocyclo containing 1-3 heteroatoms selected from N, O and S; R 4 and R 5 are independently hydrogen, C 1-4 alkyl substituted with 0-1 R f, (CH 2) r- phenyl substituted with 0-3 R d, or a -(CH 2)-5-7 membered heterocycle comprising carbon atoms and 1-4 heteroatoms selected from N, O, and S p; R 11 at each occurrence independently is hydrogen, cyclopropyl substituted with 0-3 R f, or C 1-4 alkyl substituted with 0-3 R f; R c is C 1-6 alkyl substituted with 0-3 R f; R d independently at each occurrence is F or OH; R f is halo; p is 0-2; and r is 0, 1, 2, 3, or 4. R 1 is C 1-3 alkyl optionally substituted by 0-7 R 1a; R 1a at each occurrence is independently hydrogen, deuterium, F, Cl, Br, CF 3 or CN; R 2 is C 1-6 alkyl or -(CH 2) r -3-14 membered carbocycle, each group substituted with 0-4 R 2a; R 2a at each occurrence is independently hydrogen, =O, halo, OCF 3, CN, NO 2, -(CH 2) r OR b, -(CH 2) r SR b, -(CH 2) r C R b, -(CH 2) r C OR b, -(CH 2) r OC R b, CH 2) r NR 11 R 11, -(CH 2) r C NR 11 R 11, -(CH 2) r NR b C R c, -(CH 2) r NR b C OR c, -NR b C NR 11 R 11, -S p NR 11 R 11, -NR b S p R c, -S p R c, C 1-6 alkyl substituted with 0-3 R a, C 1-6 haloalkyl, C 2-6 alkenyl substituted with 0-3 R a, C 2-6 alkynyl substituted with 0-3 R a, -(CH 2) r -3-14 membered carbocycle substituted with 0-1 R a or a -(CH 2) r -5-7 membered heterocycle comprising carbon atoms or 1-4 heteroatoms selected from N, O, and S p substituted with 0-2 R a; R 3 is R 3aa is S p R c, OR b, chloro, F, CN, NH 2, C NR 11 R 11, NR b SO p R c, NR b C R c, C 1-6 alkyl substituted with 0-3 R a or a 5- to 6-membered heteroaryl containing 1-3 heteroatoms selected from N, O, and S substituted with 0-3 R a; R 3ab, R 3ac, or R 3ad are independently hydrogen, Cl, F, Br, CN, OR b, C 1-6 alkyl substituted 0-3 R a; C NR 11 R 11, C R b, S p R c, or a 4-7 membered heterocycle containing1-3 heteroatoms selected from N, O, and S substituted with 0-3 R a; R a is OR b or halo; R b is hydrogen, C 1-6 alkyl substituted with 0-2 R d, a 5- to 7-membered heterocyclo containing 1-3 heteroatoms selected from N, O and S; R 4 and R 5 are independently hydrogen, C 1-4 alkyl substituted with 0-1 R f, (CH 2) r- phenyl substituted with 0-3 R d, or a -(CH 2)-5-7 membered heterocycle comprising carbon atoms and 1-4 heteroatoms selected from N, O, and S p; R 11 at each occurrence independently is hydrogen, cyclopropyl substituted with 0-3 R f, or C 1-4 alkyl substituted with 0-3 R f; R c is C 1-6 alkyl substituted with 0-3 R f; R d independently at each occurrence is F or OH; R f is halo; p is 0-2; and r is 0, 1, 2, 3, or 4.