A surgical instrument assembly configured to be operably attached to and detached from a surgical robot interface, wherein said surgical instrument assembly comprises: a shaft assembly, comprising: an end effector, comprising: a staple cartridge; an anvil; a first jaw; and a second jaw pivotable relative to said first jaw between an unclamped configuration and a clamped configuration; a distal end, wherein said end effector extends from said distal end of said shaft assembly; and a closure drive member configured to move said second jaw relative to said first jaw; and a control assembly, wherein said shaft assembly is operably coupled with said control assembly, and wherein said control assembly comprises: housing (5100, 5200); wherein said control assembly comprises a closure drive system configured to actuate said closure drive member, characterised in that said closure drive system comprises a rotary input drive configured to be driven by a rotary drive member of the surgical robot interface when said surgical instrument assembly is operably attached to the surgical robot interface; and an exterior closure drive actuator operably coupled to said input drive, wherein said exterior closure drive actuator is exterior to said housing, and wherein said exterior closure drive actuator is configured to be actuated by a clinician to manually rotate said rotary input drive to move said second jaw from said unclamped configuration to said clamped configuration when said surgical instrument assembly is not operably attached to the surgical robot interface. a shaft assembly, comprising: an end effector, comprising: a staple cartridge; an anvil; a first jaw; and a second jaw pivotable relative to said first jaw between an unclamped configuration and a clamped configuration; a distal end, wherein said end effector extends from said distal end of said shaft assembly; and a closure drive member configured to move said second jaw relative to said first jaw; and an end effector, comprising: a staple cartridge; an anvil; a first jaw; and a second jaw pivotable relative to said first jaw between an unclamped configuration and a clamped configuration; a staple cartridge; an anvil; a first jaw; and a second jaw pivotable relative to said first jaw between an unclamped configuration and a clamped configuration; a distal end, wherein said end effector extends from said distal end of said shaft assembly; and a closure drive member configured to move said second jaw relative to said first jaw; and a control assembly, wherein said shaft assembly is operably coupled with said control assembly, and wherein said control assembly comprises: housing (5100, 5200); wherein said control assembly comprises a closure drive system configured to actuate said closure drive member, characterised in that said closure drive system comprises a rotary input drive configured to be driven by a rotary drive member of the surgical robot interface when said surgical instrument assembly is operably attached to the surgical robot interface; and an exterior closure drive actuator operably coupled to said input drive, wherein said exterior closure drive actuator is exterior to said housing, and wherein said exterior closure drive actuator is configured to be actuated by a clinician to manually rotate said rotary input drive to move said second jaw from said unclamped configuration to said clamped configuration when said surgical instrument assembly is not operably attached to the surgical robot interface. housing (5100, 5200); wherein said control assembly comprises a closure drive system configured to actuate said closure drive member, characterised in that said closure drive system comprises a rotary input drive configured to be driven by a rotary drive member of the surgical robot interface when said surgical instrument assembly is operably attached to the surgical robot interface; and an exterior closure drive actuator operably coupled to said input drive, wherein said exterior closure drive actuator is exterior to said housing, and wherein said exterior closure drive actuator is configured to be actuated by a clinician to manually rotate said rotary input drive to move said second jaw from said unclamped configuration to said clamped configuration when said surgical instrument assembly is not operably attached to the surgical robot interface.