Process of manufacturing a tampon with integrated therapeutic means, comprising - a first step, in which a band is produced, the width of which at least approximately corresponds to the length of said tampon and which consists of absorptive cotton and/or cellulose fibers, optionally with added synthetic fibers; - a second step, in which said band is helically wound around a geometric axis, which extends transversally with respect to said band and at the same time represents a central longitudinal axis of said tampon, wherein a string is inserted among threads, the one end of which protrudes outwardly from the distal end portion of said tampon, by which a substantially cylindrical semi-product consisting of said spirally wound absorptive fibrous material is obtained; - a third step, in which said semi-product consisting of said spirally wound absorptive fibrous material is radially compressed along its overall length in several directions thereof, namely in six up to twelve directions extending equidistantly along the circumference thereof, by which ribs and grooves are formed, which are alternatively and substantially equidistantly arranged along the circumference thereof, and which extend either linearly or spirally between the proximal end portion and the distal end portion; - a fourth step, in which a substantially hemispherical tip is formed on said tampon by means of longitudinal compression in a direction of said longitudinal axis thereof, characterized in that between said third and fourth step, namely upon finishing said third step including radial compression due to forming said ribs and grooves, and prior to axial compression due to forming said tip of a tampon, the last is furnished with a blind hole, which extends coaxially with said central longitudinal axis of the tampon, upon which a therapeutic means is introduced into said hole, which is then followed by performing said fourth step, namely said compression in axial direction due to forming said tip of the tampon. - a first step, in which a band is produced, the width of which at least approximately corresponds to the length of said tampon and which consists of absorptive cotton and/or cellulose fibers, optionally with added synthetic fibers; - a second step, in which said band is helically wound around a geometric axis, which extends transversally with respect to said band and at the same time represents a central longitudinal axis of said tampon, wherein a string is inserted among threads, the one end of which protrudes outwardly from the distal end portion of said tampon, by which a substantially cylindrical semi-product consisting of said spirally wound absorptive fibrous material is obtained; - a third step, in which said semi-product consisting of said spirally wound absorptive fibrous material is radially compressed along its overall length in several directions thereof, namely in six up to twelve directions extending equidistantly along the circumference thereof, by which ribs and grooves are formed, which are alternatively and substantially equidistantly arranged along the circumference thereof, and which extend either linearly or spirally between the proximal end portion and the distal end portion; - a fourth step, in which a substantially hemispherical tip is formed on said tampon by means of longitudinal compression in a direction of said longitudinal axis thereof, characterized in that