mhurhangee/ep-ind-claims huggingface dataset:
A method of prognosing inflammatory bowel disease in an individual, comprising: assaying a sample obtained from the individual to determine the presence or absence of one or more risk variants selected from rs10001225(SEQ ID No. 2) rs4694164(SEQ ID No. 3) and rs7668327(SEQ ID No. 4), assaying the sample to determine the presence or absence of serological marker ANCA; and prognosing an aggressive form of inflammatory bowel disease in the individual based on the presence of one or more of the risk variants and the presence of serological marker ANCA. assaying a sample obtained from the individual to determine the presence or absence of one or more risk variants selected from rs10001225(SEQ ID No. 2) rs4694164(SEQ ID No. 3) and rs7668327(SEQ ID No. 4), assaying the sample to determine the presence or absence of serological marker ANCA; and prognosing an aggressive form of inflammatory bowel disease in the individual based on the presence of one or more of the risk variants and the presence of serological marker ANCA.
Elongated structure for a window frame suitable for supporting a panel for separating an inner environment from an outer environment, wherein the elongated structure comprises: - a first crosspiece defining a first abutment surface; - a second crosspiece defining a second abutment surface, parallel to the first abutment surface; - a truss structure connecting the first crosspiece and the second crosspiece; wherein the truss structure comprises rods extending from connection zones of the first crosspiece to connection zones of the second crosspiece; characterised in that the rods are tapered. - a first crosspiece defining a first abutment surface; - a second crosspiece defining a second abutment surface, parallel to the first abutment surface; - a truss structure connecting the first crosspiece and the second crosspiece;
A method for estimating frequency offset in a received signal (y) originating from a transmitted signal (x) propagated through a radio propagation channel, the method comprising: estimating (390, 570) the frequency offset from at least one phase derived (380, 410, 530, 540, 550) from the received signal, wherein a weight dependent on characteristics of the transmitted signal is applied to the phase, wherein a first set of samples (z) is calculated by scaling and de-rotating the received signal, wherein the de-rotation is configured to be dependent on phase contributions from at least one of the transmitted signal (x) and the radio propagation channel, characterized by the at least one phase used in the frequency offset estimation being derived from a plurality of correlation terms that are calculated on the first set of samples (z), wherein the weight is derived from a plurality of correlation terms that are computed based on said characteristics of the transmitted signal, and wherein the transmitted signal (x) comprises a known training sequence from which the characteristics of the transmitted signal are derived. estimating (390, 570) the frequency offset from at least one phase derived (380, 410, 530, 540, 550) from the received signal, wherein a weight dependent on characteristics of the transmitted signal is applied to the phase, wherein a first set of samples (z) is calculated by scaling and de-rotating the received signal, wherein the de-rotation is configured to be dependent on phase contributions from at least one of the transmitted signal (x) and the radio propagation channel, characterized by the at least one phase used in the frequency offset estimation being derived from a plurality of correlation terms that are calculated on the first set of samples (z), wherein the weight is derived from a plurality of correlation terms that are computed based on said characteristics of the transmitted signal, and wherein the transmitted signal (x) comprises a known training sequence from which the characteristics of the transmitted signal are derived.
A sensor comprising: at least one optical waveguide configured to emit light in a direction; and an optical reflector optically coupled to the at least one optical waveguide, the optical reflector configured to reflect at least a portion of the light, the optical reflector comprising: a first portion of the optical reflector configured to reflect a first portion of the light back to the at least one optical waveguide; and a second portion of the optical reflector configured to reflect a second portion of the light back to the at least one optical waveguide, the second portion of the optical reflector responsive to a perturbation by moving relative to the first portion of the optical reflector, characterized in that the reflected second portion of the light is differing in phase from the reflected first portion of the light by a phase difference that is not substantially equal to an integer multiple of π when the second portion of the optical reflector is in an equilibrium position in absence of the perturbation. at least one optical waveguide configured to emit light in a direction; and an optical reflector optically coupled to the at least one optical waveguide, the optical reflector configured to reflect at least a portion of the light, the optical reflector comprising: a first portion of the optical reflector configured to reflect a first portion of the light back to the at least one optical waveguide; and a second portion of the optical reflector configured to reflect a second portion of the light back to the at least one optical waveguide, the second portion of the optical reflector responsive to a perturbation by moving relative to the first portion of the optical reflector, characterized in that the reflected second portion of the light is differing in phase from the reflected first portion of the light by a phase difference that is not substantially equal to an integer multiple of π when the second portion of the optical reflector is in an equilibrium position in absence of the perturbation. a first portion of the optical reflector configured to reflect a first portion of the light back to the at least one optical waveguide; and a second portion of the optical reflector configured to reflect a second portion of the light back to the at least one optical waveguide, the second portion of the optical reflector responsive to a perturbation by moving relative to the first portion of the optical reflector, characterized in that the reflected second portion of the light is differing in phase from the reflected first portion of the light by a phase difference that is not substantially equal to an integer multiple of π when the second portion of the optical reflector is in an equilibrium position in absence of the perturbation.
Use of VEGF-A isoform VEGF 145 or VEGF 189 for the manufacture of a medicament to treat any of frontotemporal lobe dementia, Alzheimer's disease, Parkinson's disease, Huntington's disease, and motor neuron disorders.
A water pump, comprising: a driving rotary body being drivingly rotated by a drive mechanism; a pump shaft rotating by a power transmission from the driving rotary body; a housing, the pump shaft being inserted in the housing; an impeller being fixed at one end side of the pump shaft; an electromagnetic clutch including a clutch portion being disposed at the other end side of the pump shaft, the clutch portion switching on and off the power transmission from the driving rotary body to the pump shaft; a mechanical seal being disposed at a position between the impeller and the clutch portion, the mechanical seal being mounted between the pump shaft and the housing; and a liquid storage space allowing to store a liquid leaking out from a side of the impeller to a side of the clutch portion via the mechanical seal; wherein the electromagnetic clutch includes a yoke holding an electromagnetic coil; the liquid storage space is formed at the housing; the yoke is in contact with the housing; characterized in that the housing is formed with an opening portion opening the liquid storage space to a side of the yoke; and the yoke is positioned so as to close an outer circumferential side portion of the opening portion of the liquid storage space into which the liquid leaking out via the mechanical seal flows by its own weight. a driving rotary body being drivingly rotated by a drive mechanism; a pump shaft rotating by a power transmission from the driving rotary body; a housing, the pump shaft being inserted in the housing; an impeller being fixed at one end side of the pump shaft; an electromagnetic clutch including a clutch portion being disposed at the other end side of the pump shaft, the clutch portion switching on and off the power transmission from the driving rotary body to the pump shaft; a mechanical seal being disposed at a position between the impeller and the clutch portion, the mechanical seal being mounted between the pump shaft and the housing; and a liquid storage space allowing to store a liquid leaking out from a side of the impeller to a side of the clutch portion via the mechanical seal; wherein the electromagnetic clutch includes a yoke holding an electromagnetic coil; the liquid storage space is formed at the housing; the yoke is in contact with the housing; characterized in that the housing is formed with an opening portion opening the liquid storage space to a side of the yoke; and the yoke is positioned so as to close an outer circumferential side portion of the opening portion of the liquid storage space into which the liquid leaking out via the mechanical seal flows by its own weight.
An electrochemical cell, comprising: a negative electrode including a form of lithium; a positive electrode spaced apart from the negative electrode and including an electron conducting matrix; a separator positioned between the negative electrode and the positive electrode; an electrolyte including a salt; and a charging redox couple located within the positive electrode, wherein the electrochemical cell is characterized by the transfer of electrons from a discharge product located in the positive electrode to the electron conducting matrix by the charging redox couple during a charge cycle, wherein the charging redox couple is at least partially dissolved in the electrolyte, characterized in that a protective layer is provided between the negative electrode and the positive electrode configured to block transport of an oxidized species of the charging redox couple to the negative electrode. a negative electrode including a form of lithium; a positive electrode spaced apart from the negative electrode and including an electron conducting matrix; a separator positioned between the negative electrode and the positive electrode; an electrolyte including a salt; and a charging redox couple located within the positive electrode, wherein the electrochemical cell is characterized by the transfer of electrons from a discharge product located in the positive electrode to the electron conducting matrix by the charging redox couple during a charge cycle, wherein the charging redox couple is at least partially dissolved in the electrolyte, characterized in that a protective layer is provided between the negative electrode and the positive electrode configured to block transport of an oxidized species of the charging redox couple to the negative electrode.
A device comprising an ossicular prosthesis and an elongate applicator, in which case the prosthesis, designed to replace or bridge at least one element of the human ossicular chain, comprises a first fastening element at one end for mechanical connection to the tympanic membrane or an element of the ossicular chain, a second fastening element at its other end for mechanical connection to another element or parts of an element of the ossicular chain or for direct connection to the inner ear, and an elongate connecting element which joins together the two fastening elements (41 and 12) in a sound-conducting manner, and in which case the elongate applicator, provided for transferring the ossicular prosthesis from a sterile package to the operation site and inserting it into the middle ear or auditory canal, has a first free end extending away from the ossicular prosthesis for handling purposes, and at its other end an engagement portion, said engagement portion of the applicator being gripped in a force- and/or form-locking manner by a receiving portion connected to the ossicular prosthesis, characterized in that the receiving portion takes the form of a sleeve which is open in direction of the engagement portion of the applicator and which has a cylindrical or conical bore in which a conical end section of the engagement portion can engage.
Use of an alkaline aqueous composition for coating an aluminum or aluminum alloy substrate, the composition comprising: an aqueous carrier; one or more Group IA metal ions; a hydroxide; and a phosphate, wherein at least one of the Group 1A metal ions is a lithium ion, the composition has a pH of greater than 10 and is substantially free of Group 3 through Group 12 metals (transition metals), chromates, other metallates and oxidizing agents. an aqueous carrier; one or more Group IA metal ions; a hydroxide; and a phosphate, wherein at least one of the Group 1A metal ions is a lithium ion, the composition has a pH of greater than 10 and is substantially free of Group 3 through Group 12 metals (transition metals), chromates, other metallates and oxidizing agents.
A strain relief for a coaxial cable and coaxial connector interconnection, the coaxial cable provided with an outer conductor having corrugations and the coaxial connector provided with a connector body with a bore, the strain relief comprising: an injection moldable polymer material surrounding the interconnection; characterized in the injection moldable polymer material filling a solder pre-form cavity between the outer conductor of the coaxial cable, a solder joint and an inner diameter of the bore of the connector body. an injection moldable polymer material surrounding the interconnection; characterized in the injection moldable polymer material filling a solder pre-form cavity between the outer conductor of the coaxial cable, a solder joint and an inner diameter of the bore of the connector body.
Method for immobilising and processing functional multi-component structures of the extracellular matrix, comprising the following successive method steps: a) covalent bonding of an adhesion promoter layer composed of carboxylic acid-bearing polymers, including maleic anhydride copolymers and polyacrylates, to cell culture carriers; b) cultivation of mesenchymal stem cells on the adhesion promoter layer and subsequent immobilisation of the extracellular matrix secreted by the cells through deposition and connection to the adhesion promoter layer; whereby the adhesion promoter layer serves to stabilise the extracellular matrix secreted by the cells, and c) application of a decellularisation protocol in order to remove the matrix-secreting cells from the surface whilst simultaneously maintaining the structure and functionality of the underlying, immobilised extracellular matrix connected with the adhesion promoter; and d) the functionalisation of the extracellular matrix processed according to method steps a) to c) with signalling modules, characterised in that in method step c) the mesenchymal stem cell layers and extracellular matrix layers are incubated in a decellularisation solution, which is composed of 5 percent Triton x-100 and 20 mM ammonium hydroxide (NH40H) in a phosphate-buffered saline solution, in a temperature range of between 35°C to 39 °C and are then washed with a phosphate-buffered saline solution. a) covalent bonding of an adhesion promoter layer composed of carboxylic acid-bearing polymers, including maleic anhydride copolymers and polyacrylates, to cell culture carriers; b) cultivation of mesenchymal stem cells on the adhesion promoter layer and subsequent immobilisation of the extracellular matrix secreted by the cells through deposition and connection to the adhesion promoter layer; whereby the adhesion promoter layer serves to stabilise the extracellular matrix secreted by the cells, and c) application of a decellularisation protocol in order to remove the matrix-secreting cells from the surface whilst simultaneously maintaining the structure and functionality of the underlying, immobilised extracellular matrix connected with the adhesion promoter; and d) the functionalisation of the extracellular matrix processed according to method steps a) to c) with signalling modules, characterised in that in method step c) the mesenchymal stem cell layers and extracellular matrix layers are incubated in a decellularisation solution, which is composed of 5 percent Triton x-100 and 20 mM ammonium hydroxide (NH40H) in a phosphate-buffered saline solution, in a temperature range of between 35°C to 39 °C and are then washed with a phosphate-buffered saline solution.
An electron beam emission device comprising: a housing defining a space for electron beams acceleration, and comprising an emission port for emission of the electron beams; a cathode disposed in the housing, and configured to emit the electrons; an anode positioned in the housing opposite and spaced apart from the cathode, and configured to accelerate the electrons emitted from the cathode; and an insulation holder which insulates a portion between the cathode and the housing, and fixes the cathode, wherein the cathode comprises a concave surface which faces the anode, characterised in that the cathode further comprises a rounded rim surrounding the concave surface, and wherein the insulation holder is formed to surround a rear surface of the concave surface of the cathode, and to surround a lateral surface of the cathode, the insulation holder extending to the rounded rim of the cathode, and wherein a surface of the cathode, which faces the anode, is disposed to be closer to the anode than the insulation holder. a housing defining a space for electron beams acceleration, and comprising an emission port for emission of the electron beams; a cathode disposed in the housing, and configured to emit the electrons; an anode positioned in the housing opposite and spaced apart from the cathode, and configured to accelerate the electrons emitted from the cathode; and an insulation holder which insulates a portion between the cathode and the housing, and fixes the cathode, wherein the cathode comprises a concave surface which faces the anode, characterised in that the cathode further comprises a rounded rim surrounding the concave surface, and wherein the insulation holder is formed to surround a rear surface of the concave surface of the cathode, and to surround a lateral surface of the cathode, the insulation holder extending to the rounded rim of the cathode, and wherein a surface of the cathode, which faces the anode, is disposed to be closer to the anode than the insulation holder.
A process for removing mercury impurities from gaseous hydrocarbon streams comprising a mixture of saturated hydrocarbons and unsaturated hydrocarbons, wherein said hydrocarbons contain acetylene or acetylenic hydrocarbons; said process comprising: a) providing a fluid stream containing elemental mercury; b) passing said fluid stream into a regenerable fixed adsorption bed containing an adsorbent on which said mercury is preferentially adsorbed whereby mercury is adsorbed, a mercury mass transfer front is established and a purified product effluent is recovered; c) terminating the flow into said regenerable bed prior to breakthrough of the mercury mass transfer front; d) regenerating said regenerable bed by passing therethrough a purge desorbent whereby mercury is desorbed and removed from said bed in a regenerant effluent stream, wherein said purge desorbent is a portion of a demethanizer overhead stream from a separation section of an ethylene plant; and e) passing said regenerant effluent stream into a nonregenerable fixed adsorbent bed comprising a composite comprising alumina and copper sulfide to remove mercury from said regenerant effluent stream. a) providing a fluid stream containing elemental mercury; b) passing said fluid stream into a regenerable fixed adsorption bed containing an adsorbent on which said mercury is preferentially adsorbed whereby mercury is adsorbed, a mercury mass transfer front is established and a purified product effluent is recovered; c) terminating the flow into said regenerable bed prior to breakthrough of the mercury mass transfer front; d) regenerating said regenerable bed by passing therethrough a purge desorbent whereby mercury is desorbed and removed from said bed in a regenerant effluent stream, wherein said purge desorbent is a portion of a demethanizer overhead stream from a separation section of an ethylene plant; and e) passing said regenerant effluent stream into a nonregenerable fixed adsorbent bed comprising a composite comprising alumina and copper sulfide to remove mercury from said regenerant effluent stream.
Control device for controlling a brake system of a vehicle (10; 92; 132; 238), having ABS lines (40; 66) which lead from the control device (17; 99; 125; 141; 244) to wheel speed sensors (38; 60), - wherein the vehicle (10; 92; 132; 238) has a supporting structure (222; 240) and a cabin (224; 242) which is supported by the supporting structure (222; 240) and has at least one driver's seat, - wherein the control device (17; 99; 125; 141; 244) can be arranged outside the cabin (224; 242) on the supporting structure (222; 240), characterized in that - the ABS lines (40; 66) which lead from the control device (17; 99; 125; 141; 244) to wheel speed sensors (38; 60) are used as antennas for receiving signals from tyre pressure monitoring modules which detect the tyre pressure and are mounted on or in wheels (20; 56) or tyre valves of the vehicle (10; 92; 132; 238) or are used as electrical feed lines to antennas which are mounted in wheel housings of the vehicle (10; 92; 132; 238) and have the purpose of receiving signals of the tyre pressure monitoring modules. - wherein the vehicle (10; 92; 132; 238) has a supporting structure (222; 240) and a cabin (224; 242) which is supported by the supporting structure (222; 240) and has at least one driver's seat, - wherein the control device (17; 99; 125; 141; 244) can be arranged outside the cabin (224; 242) on the supporting structure (222; 240), - the ABS lines (40; 66) which lead from the control device (17; 99; 125; 141; 244) to wheel speed sensors (38; 60) are used as antennas for receiving signals from tyre pressure monitoring modules which detect the tyre pressure and are mounted on or in wheels (20; 56) or tyre valves of the vehicle (10; 92; 132; 238) or are used as electrical feed lines to antennas which are mounted in wheel housings of the vehicle (10; 92; 132; 238) and have the purpose of receiving signals of the tyre pressure monitoring modules.