mhurhangee/ep-ind-claims huggingface dataset:
An isolated Pichia host cell lacking functional CRZ1 polypeptide of SEQ ID NO: 3 comprising a heterologous polynucleotide that encodes a heterologous polypeptide, wherein the heterologous polypeptide is an immunoglobulin.
A stacking device for stacking a plurality of shaped steel products, comprising: a stacking platform (1, 11) to be loaded with the shaped steel products (4, 14-1, 14-2, 14-3) in a stacked manner; a transferring platform (2, 12) having multiple loading surfaces to be loaded with at least one of the shaped steel products (4, 14-1, 14-2, 14-3) to be transferred to the stacking platform (1, 11); and a pushing means (3, 13) for pushing the at least one of the shaped steel products (4, 14-1, 14-2, 14-3) loaded on the transferring platform (2, 12) toward the stacking platform (1, 11) along a pushing direction, characterized in that the transferring platform (2, 12) is a rotating body rotatable around an axis that is parallel to the pushing direction along which the pushing means pushes, and comprises on its circumference a first loading surface (5, 15) having a flat portion and a second loading surface (6, 16) having a flat portion and an inclined portion, the flat portion and the inclined portion being formed along the pushing direction, the inclined portion being formed on a side facing the stacking platform (1, 11), and the first and second loading surfaces (5, 15; 6, 16) being selectable to be loaded with at least one of the shaped steel products (4, 14-1, 14-2, 14-3) to be transferred according to the order in which the shaped steel products (4, 14-1, 14-2, 14-3) are pushed. a stacking platform (1, 11) to be loaded with the shaped steel products (4, 14-1, 14-2, 14-3) in a stacked manner; a transferring platform (2, 12) having multiple loading surfaces to be loaded with at least one of the shaped steel products (4, 14-1, 14-2, 14-3) to be transferred to the stacking platform (1, 11); and a pushing means (3, 13) for pushing the at least one of the shaped steel products (4, 14-1, 14-2, 14-3) loaded on the transferring platform (2, 12) toward the stacking platform (1, 11) along a pushing direction,
A module for use in skin surgery comprising: a main body opened at both sides and having an inner space; a reciprocating assembly built in the main body, the reciprocating assembly being moved forward and backward in the lengthwise direction of the main body through a screw-coupling while rotating forward and backward; a needle assembly built in the main body in such a way as to come into contact with the reciprocating assembly while enabling the reciprocating assembly to be rotated, the needle assembly including a plurality of needles (401', 401) which retract or extend through one end portion of the main body; and a guide suction assembly, one end of which comes into contact with the skin such that ends of the needles (401', 401) are respectively retracted or extended, the guide suction assembly to which one end portion of the main body is rotatably coupled, the guide suction assembly communicating with the skin coming in close contact with the end portion thereof so as to suck air. a main body opened at both sides and having an inner space; a reciprocating assembly built in the main body, the reciprocating assembly being moved forward and backward in the lengthwise direction of the main body through a screw-coupling while rotating forward and backward; a needle assembly built in the main body in such a way as to come into contact with the reciprocating assembly while enabling the reciprocating assembly to be rotated, the needle assembly including a plurality of needles (401', 401) which retract or extend through one end portion of the main body; and a guide suction assembly, one end of which comes into contact with the skin such that ends of the needles (401', 401) are respectively retracted or extended, the guide suction assembly to which one end portion of the main body is rotatably coupled, the guide suction assembly communicating with the skin coming in close contact with the end portion thereof so as to suck air.
A catheter, comprising: an elongated shaft having a proximal section and a distal section, a channel (162, 164, 166) for accessing the distal end of the shaft, a guide wire channel extending along at least a portion of the shaft to the distal end of the shaft, a guide wire port disposed at or near the transition between the proximal section and the distal section of the shaft, the guide wire port defining a guide wire port opening and a guide wire port conduit that communicate with the guide wire channel of the shaft such that a guide wire may be insertable into the guide wire port opening and routed into the guide wire channel; and a deflector associated with the guide wire port and configured to move between the guide wire port conduit and the guide wire channel. an elongated shaft having a proximal section and a distal section, a channel (162, 164, 166) for accessing the distal end of the shaft, a guide wire channel extending along at least a portion of the shaft to the distal end of the shaft, a guide wire port disposed at or near the transition between the proximal section and the distal section of the shaft, the guide wire port defining a guide wire port opening and a guide wire port conduit that communicate with the guide wire channel of the shaft such that a guide wire may be insertable into the guide wire port opening and routed into the guide wire channel; and a deflector associated with the guide wire port and configured to move between the guide wire port conduit and the guide wire channel.
A method of making a stator comprising: positioning an inner tubular member having an inner surface within an outer tubular member; and installing a rigid mandrel within the inner tubular member; the method characterised by applying a compressive force to the inner tubular member and the outer tubular member, the compressive force causing the inner tubular member to be connected to the outer tubular member. positioning an inner tubular member having an inner surface within an outer tubular member; and installing a rigid mandrel within the inner tubular member; the method characterised by applying a compressive force to the inner tubular member and the outer tubular member, the compressive force causing the inner tubular member to be connected to the outer tubular member.
A multi-cell carrier for battery cells, comprising: a semi-rigid elastomeric carrier having a plurality of closely spaced apart, substantially parallel and substantially cylindrical channels, wherein each channel has an outer wall and a length, with neighboring channels sharing a sidewall therebetween, wherein at least some of the channels include at least one vent extending though the outer wall, wherein the channels are sized and configured to hold at least a major portion of a length of a respective battery cell, characterized in that at least one outwardly extending member extends outwardly from a channel outer wall in a direction substantially orthogonal to an axially extending centerline of the channels. a semi-rigid elastomeric carrier having a plurality of closely spaced apart, substantially parallel and substantially cylindrical channels, wherein each channel has an outer wall and a length, with neighboring channels sharing a sidewall therebetween, wherein at least some of the channels include at least one vent extending though the outer wall, wherein the channels are sized and configured to hold at least a major portion of a length of a respective battery cell, characterized in that at least one outwardly extending member extends outwardly from a channel outer wall in a direction substantially orthogonal to an axially extending centerline of the channels.
A process for preparing a compound of formula: comprising the steps of: i) coupling an amide of formula: with a pyrimidine compound of formula: in an aprotic organic solvent in the presence of a base, to form, after quenching with an acid, an intermediate of formula and ii) at a pH >5, optionally in the presence of added N,O -dimethylhydroxylamine or a salt thereof, allowing the mixture to react to form the compound of formula, wherein: R 1 is phenyl, or a 5 to 6-membered heteroaryl ring; optionally substituted with up to three instances independently selected from the group consisting of halogen or methyl; wherein said 5 or 6-membered heteroaryl ring contains up to 3 ring atoms selected from the group consisting of N, S or O. i) coupling an amide of formula: with a pyrimidine compound of formula: in an aprotic organic solvent in the presence of a base, to form, after quenching with an acid, an intermediate of formula and with a pyrimidine compound of formula: in an aprotic organic solvent in the presence of a base, to form, after quenching with an acid, an intermediate of formula and ii) at a pH >5, optionally in the presence of added N,O -dimethylhydroxylamine or a salt thereof, allowing the mixture to react to form the compound of formula, wherein: R 1 is phenyl, or a 5 to 6-membered heteroaryl ring; optionally substituted with up to three instances independently selected from the group consisting of halogen or methyl; wherein said 5 or 6-membered heteroaryl ring contains up to 3 ring atoms selected from the group consisting of N, S or O.
A method of determining a stiffness of a tissue with ultrasound, the method comprising the steps of: forming a baseline image of a region of interest with an ultrasound imaging system having a point source transmit aperture transmitting an unfocused ultrasonic pulse; transmitting an unfocused ultrasonic pulse to induce a propagating shear wave in the region of interest; imaging the region of interest with the ultrasound imaging system at a frame rate sufficient to detect the propagating shear wave to form a plurality of image frames of the region of interest as the propagating shear wave moves through the region of interest; subtracting the baseline image from at least two of the formed image frames to obtain at least two difference frames; determining a position of the propagating shear wave in the at least two difference frames; calculating a propagation speed of the propagating shear wave in the region of interest from the positions in the at least two difference frames; and calculating a tissue stiffness of the region of interest from the propagation speed. forming a baseline image of a region of interest with an ultrasound imaging system having a point source transmit aperture transmitting an unfocused ultrasonic pulse; transmitting an unfocused ultrasonic pulse to induce a propagating shear wave in the region of interest; imaging the region of interest with the ultrasound imaging system at a frame rate sufficient to detect the propagating shear wave to form a plurality of image frames of the region of interest as the propagating shear wave moves through the region of interest; subtracting the baseline image from at least two of the formed image frames to obtain at least two difference frames; determining a position of the propagating shear wave in the at least two difference frames; calculating a propagation speed of the propagating shear wave in the region of interest from the positions in the at least two difference frames; and calculating a tissue stiffness of the region of interest from the propagation speed.
Goggles, comprising: a pair of eyecups (110L,110R) having a lens part; a nose bridge including a plurality of hooking parts arrayed in a length direction at one or more ends and for connecting facing ends of the eyecups; and a band holder extended from at least one of the facing ends of the eyecups and for accommodating and fixing one end of the nose bridge, wherein the band holder includes a through hole formed at a free end and through which one end of the nose bridge passes, a first fixing pin positioned in the through hole and hooked to the hooking part of the nose bridge, and a pair of second fixing pins positioned in the through hole with the first fixing pin therebetween and hooked to a transverse edge of the nose bridge.
Rotating blade for a gas turbine, comprising an airfoil extending in a longitudinal direction and having a leading edge and a trailing edge, whereby said airfoil is bordered at its outer end by a tip shroud, whereby said airfoil comprises two or more internal passages (15a, 15b and 15c), which run in longitudinal direction and are separated by solid webs (23 and 24), and whereby a plurality of shroud fins (18a, 18b and 18c) are arranged on top of said tip shroud to improve gas sealing against a corresponding stator heat shield, the position of each of said shroud fins (18a, 18b and 18c) is selected to be exclusively above, along the longitudinal direction, one of said webs (23, 24) and/or a leading edge wall; the rotating blade being characterized in that on a longitudinally outer surface of said tip shroud and behind, along a direction towards the trailing edge, the shroud fin provided at the leading edge of said blade one or more small fins (21, 22) are provided to increase the heat transfer to a colder surrounding medium for increased cooling of a floor of said tip shroud; wherein said small fins (21, 22) are aligned with the rotating direction of the blade to minimise a breaking effect and improve the mechanical stability of tip shroud against bending upwards due to the centrifugal force.
A surgical light comprising: a light housing having at least one light source therein; a handle assembly extending from the light housing, the handle assembly including a knob and a cover; the handle assembly being rotatably connected to the light housing; the cover covering the knob; wherein the handle assembly is configured such that engaging the cover in a first mode and rotating the knob relative to the light housing alters a first characteristic of light emitted from the at least one light source; characterised in that the handle assembly is configured such that engaging the cover in a second mode and rotating the knob relative to the light housing alters a second characteristic of light emitted from the at least one light source. a light housing having at least one light source therein; a handle assembly extending from the light housing, the handle assembly including a knob and a cover; the handle assembly being rotatably connected to the light housing; the cover covering the knob; wherein the handle assembly is configured such that engaging the cover in a first mode and rotating the knob relative to the light housing alters a first characteristic of light emitted from the at least one light source; characterised in that the handle assembly is configured such that engaging the cover in a second mode and rotating the knob relative to the light housing alters a second characteristic of light emitted from the at least one light source.
An avalanche and the like protection element comprising a protection surface, beams supporting said protection surface, a stem developing in a direction with respect to said protection surface, and first tensile-stressed connection elements, said beams being connected to a first portion of said stem by connecting means and being further connected to an end of said stem by said first tensile-stressed connection elements, characterised in that it further comprises a rod (6; 36) developing in an opposite direction to the developing direction of said stem with respect to said protection surface, and second tensile-stressed connection elements connected to said beams, said rod (6; 36) supporting said second tensile-stressed connection elements.
A system for modulating permeability of the blood brain barrier, the system comprising: a transcranial magnetic stimulation coil for transcranial magnetic stimulation configured to be placed on a scalp and to provide a series of magnetic pulses to the brain wherein the system is configured to provide said pulses in a range of at least 0.2 Hz stimulation frequency, and at least 100 stimulation pulses, and the system is characterized in that said system is configured to provide said pulses at an amplitude of at least 120% of the resting motor threshold stimulation amplitude. a transcranial magnetic stimulation coil for transcranial magnetic stimulation configured to be placed on a scalp and to provide a series of magnetic pulses to the brain wherein the system is configured to provide said pulses in a range of at least 0.2 Hz stimulation frequency, and at least 100 stimulation pulses, and the system is characterized in that said system is configured to provide said pulses at an amplitude of at least 120% of the resting motor threshold stimulation amplitude.
A light-emitting device, comprising an encapsulation housing and a light engine arranged in the encapsulation housing, wherein the light engine is arranged in the encapsulation housing in such a manner that a cavity is formed between the light engine and the encapsulation housing, wherein at least the exit surface of a light source arranged on one side of the light engine is located in the cavity, characterized in that the encapsulation housing comprises a first housing portion and a second housing portion, wherein the first housing portion comprises a receiving groove for receiving the second housing portion, the receiving groove is separated from the cavity by the light engine, and the other side of the light engine opposite to the side arranged with the light source is closed by the second housing portion.
A method for displaying a front-view of a vehicle's surrounding, the method comprising the steps of: capturing camera images of the vehicle's surrounding through a wide-angle or fisheye lens of a vehicle camera on an image sensor of said vehicle camera, said camera images comprising a plurality of camera pixels; transforming said captured camera images by a processing unit into display images corresponding to images being projected in parallel onto a projection plane being parallel to an image sensor plane of said image sensor, wherein a virtual plane being divided into a plurality of virtual pixels is defined at a predetermined distance from the vehicle camera, wherein the projection of each virtual pixel onto the camera image through the lens is computed, and wherein the display image is generated, the display image having a plurality of display pixels, each display pixel being associated with a corresponding virtual pixel, and wherein each display pixel is generated by interpolating and/or averaging and/or filtering over the camera pixels lying in a vicinity of the projection of the associated virtual pixel; and displaying said display images on a display device for viewing by a driver of said vehicle. capturing camera images of the vehicle's surrounding through a wide-angle or fisheye lens of a vehicle camera on an image sensor of said vehicle camera, said camera images comprising a plurality of camera pixels; transforming said captured camera images by a processing unit into display images corresponding to images being projected in parallel onto a projection plane being parallel to an image sensor plane of said image sensor, wherein a virtual plane being divided into a plurality of virtual pixels is defined at a predetermined distance from the vehicle camera, wherein the projection of each virtual pixel onto the camera image through the lens is computed, and wherein the display image is generated, the display image having a plurality of display pixels, each display pixel being associated with a corresponding virtual pixel, and wherein each display pixel is generated by interpolating and/or averaging and/or filtering over the camera pixels lying in a vicinity of the projection of the associated virtual pixel; and displaying said display images on a display device for viewing by a driver of said vehicle.
A composition comprising: a modified hepatitis E virus capsid protein comprising a portion of an HEV ORF 2 protein and a heterologous peptide, wherein the heterologous peptide is inserted into a portion of HEV ORF 2 within a pre-selected region corresponding to residues 483-490, residues 530-535, residues 554-561, residues 573-577, residues 582-593, or residues 601-613 of SEQ ID NO:1; and a heterologous nucleic acid encapsulated in a chimeric virus-like particle formed by the modified HEV capsid protein. a modified hepatitis E virus capsid protein comprising a portion of an HEV ORF 2 protein and a heterologous peptide, wherein the heterologous peptide is inserted into a portion of HEV ORF 2 within a pre-selected region corresponding to residues 483-490, residues 530-535, residues 554-561, residues 573-577, residues 582-593, or residues 601-613 of SEQ ID NO:1; and a heterologous nucleic acid encapsulated in a chimeric virus-like particle formed by the modified HEV capsid protein.
A high-frequency electric field coupler used in a contactless communication system propagating high frequency signals in a wide band utilizing electric field coupling, comprising: a coupling electrode; and a resonance unit operating to increase the amplitude of electrical charge accumulated at the coupling electrode at a predetermined resonance frequency, wherein the coupling electrode is formed by a coiled linear conductor. a coupling electrode; and a resonance unit operating to increase the amplitude of electrical charge accumulated at the coupling electrode at a predetermined resonance frequency, wherein the coupling electrode is formed by a coiled linear conductor.