mhurhangee/ep-ind-claims huggingface dataset:
A two-part, selectively dockable robotic system providing counterbalanced stabilization during performance of an operation on an underwater target structure, comprising: a first underwater robotic vehicle sized and shaped to at least partially surround the underwater target structure; a second underwater robotic vehicle sized and shaped to at least partially surround the underwater target structure and be at least partially orientated in a position opposite the first underwater robotic vehicle; complimentary docking mechanisms supported by the first and second underwater robotic vehicles and arranged so the first and second underwater robotic vehicles can selectively couple to each other with the underwater target structure disposed at least partially between the first and second underwater robotic vehicles; a tool for exerting a first force against the underwater target structure in a first direction, the tool being supported by one of the first and second underwater robotic vehicles; and a stabilization module for exerting a second force against the underwater target structure in a second direction to at least partially counteract the first force, the stabilization module being supported by one of the first and second underwater robotic vehicles. a first underwater robotic vehicle sized and shaped to at least partially surround the underwater target structure; a second underwater robotic vehicle sized and shaped to at least partially surround the underwater target structure and be at least partially orientated in a position opposite the first underwater robotic vehicle; complimentary docking mechanisms supported by the first and second underwater robotic vehicles and arranged so the first and second underwater robotic vehicles can selectively couple to each other with the underwater target structure disposed at least partially between the first and second underwater robotic vehicles; a tool for exerting a first force against the underwater target structure in a first direction, the tool being supported by one of the first and second underwater robotic vehicles; and a stabilization module for exerting a second force against the underwater target structure in a second direction to at least partially counteract the first force, the stabilization module being supported by one of the first and second underwater robotic vehicles.
A compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein: L-Ar is Ar is R 1 is H, -CN, halogen, C 1 -C 4 alkyl, -O-(C 3 -C 5 cycloalkyl), -O-(4- to 6-membered heterocycle) or -O-(C 1 -C 4 alkyl), wherein when R 1 is not H, -CN or halogen, R 1 is optionally substituted with one or more halogen; each R 2 is independently hydrogen, halogen or C 1 -C 4 alkyl; R 3 is H or F; R 21 is H, halogen, C 1 -C 4 alkyl, C 3 -C 5 cycloalkyl or 4- to 6-membered heterocycle; R 22 is H, halogen or C 1 -C 2 alkyl; R 24 is -O-(C 1 -C 4 alkyl)-O-(C 1 -C 4 alkyl), -O-(C 3 -C 5 cycloalkyl), or -O-(4- to 6-membered heterocycle), wherein R 24 is substituted with one or more hydroxyl or halogen; or R 24 is -O-(C 1 -C 4 alkyl) substituted with one or more hydroxyl; and R 25 is H, halogen, C 1 -C 4 alkyl or C 3 -C 5 cycloalkyl, wherein R 25 is optionally substituted with one or more halogen. or a pharmaceutically acceptable salt thereof, wherein: L-Ar is Ar is R 1 is H, -CN, halogen, C 1 -C 4 alkyl, -O-(C 3 -C 5 cycloalkyl), -O-(4- to 6-membered heterocycle) or -O-(C 1 -C 4 alkyl), wherein when R 1 is not H, -CN or halogen, R 1 is optionally substituted with one or more halogen; each R 2 is independently hydrogen, halogen or C 1 -C 4 alkyl; R 3 is H or F; R 21 is H, halogen, C 1 -C 4 alkyl, C 3 -C 5 cycloalkyl or 4- to 6-membered heterocycle; R 22 is H, halogen or C 1 -C 2 alkyl; R 24 is -O-(C 1 -C 4 alkyl)-O-(C 1 -C 4 alkyl), -O-(C 3 -C 5 cycloalkyl), or -O-(4- to 6-membered heterocycle), wherein R 24 is substituted with one or more hydroxyl or halogen; or R 24 is -O-(C 1 -C 4 alkyl) substituted with one or more hydroxyl; and R 25 is H, halogen, C 1 -C 4 alkyl or C 3 -C 5 cycloalkyl, wherein R 25 is optionally substituted with one or more halogen.
A combination for the treatment of prostate cancer, comprising (i) one of a benzoheterocyclic compound, a pharmaceutically acceptable salt, a solvate, a polymorph, a co-crystal, a stereoisomer and an isotope compound thereof, and (ii) an androgen receptor pathway modulator; wherein, the benzoheterocyclic compound is selected from the group consisting of: and the androgen receptor pathway modulator is selected from: wherein, the benzoheterocyclic compound is selected from the group consisting of: and the androgen receptor pathway modulator is selected from:
A system comprising: a stimulation generator that is configured to deliver a left-ventricular pacing pulse to a left ventricular chamber of a heart, and to deliver a right-ventricular pacing pulse to a right ventricular chamber of the heart; and a processor that is configured to detect at least one of an atrial sensing event or an atrial pacing event of an atrial chamber of the heart, wherein the processor is configured to determine a time interval between at least one of the atrial sensing event or the atrial pacing event of the atrial chamber of the heart and a ventricular sensing event of the ventricular chamber of the heart during a first cardiac cycle, determine a left-ventricular pacing interval based on the time interval, wherein the left-ventricular pacing interval is less than the time interval, and determine a right-ventricular pacing interval based on the time interval, wherein the right-ventricular pacing interval is greater than the left-ventricular pacing interval and less than the time interval, and wherein the processor is configured to control the stimulation generator to deliver the left-ventricular pacing pulse upon expiration of the left-ventricular pacing interval that begins at detection of at least one of the atrial sensing event or the atrial pacing event of the atrial chamber during a second cardiac cycle, and deliver the right-ventricular pacing pulse upon expiration of the right-ventricular pacing interval that begins at detection of at least one of the atrial sensing event or the atrial pacing event of the atrial chamber during the second cardiac cycle. a stimulation generator that is configured to deliver a left-ventricular pacing pulse to a left ventricular chamber of a heart, and to deliver a right-ventricular pacing pulse to a right ventricular chamber of the heart; and a processor that is configured to detect at least one of an atrial sensing event or an atrial pacing event of an atrial chamber of the heart, wherein the processor is configured to determine a time interval between at least one of the atrial sensing event or the atrial pacing event of the atrial chamber of the heart and a ventricular sensing event of the ventricular chamber of the heart during a first cardiac cycle, determine a left-ventricular pacing interval based on the time interval, wherein the left-ventricular pacing interval is less than the time interval, and determine a right-ventricular pacing interval based on the time interval, wherein the right-ventricular pacing interval is greater than the left-ventricular pacing interval and less than the time interval, and wherein the processor is configured to control the stimulation generator to deliver the left-ventricular pacing pulse upon expiration of the left-ventricular pacing interval that begins at detection of at least one of the atrial sensing event or the atrial pacing event of the atrial chamber during a second cardiac cycle, and deliver the right-ventricular pacing pulse upon expiration of the right-ventricular pacing interval that begins at detection of at least one of the atrial sensing event or the atrial pacing event of the atrial chamber during the second cardiac cycle.
A process of detecting Neisseria meningitidis in a sample comprising: a. producing an amplification product by amplifying a Neisseria meningitidis nucleotide sequence using a forward primer that hybridizes to a region within the sodC gene or sodC mRNA of Neisseria meningitidis, and a reverse primer that hybridizes to a region within the sodC gene or sodC mRNA of Neisseria meningitidis, under conditions suitable for a polymerase chain reaction; and b. detecting said amplification product to detect the Neisseria meningitidis in said sample. a. producing an amplification product by amplifying a Neisseria meningitidis nucleotide sequence using a forward primer that hybridizes to a region within the sodC gene or sodC mRNA of Neisseria meningitidis, and a reverse primer that hybridizes to a region within the sodC gene or sodC mRNA of Neisseria meningitidis, under conditions suitable for a polymerase chain reaction; and b. detecting said amplification product to detect the Neisseria meningitidis in said sample.
A method, performed by a wireless device, for communicating within a telecommunications network, the method comprising: while in a Radio Resource Control, RRC, INACTIVE state, transmitting, to a base station, a request to resume communication, characterised by: arid, without entering an RRC CONNECTED state, receiving, from the base station, an instruction to release and redirect; and in response to receiving the instruction to release and redirect, performing cell selection in a Radio Access Technology, RAT, and attempting to establish or resume communication with a selected cell. arid, without entering an RRC CONNECTED state, receiving, from the base station, an instruction to release and redirect; and in response to receiving the instruction to release and redirect, performing cell selection in a Radio Access Technology, RAT, and attempting to establish or resume communication with a selected cell.
An apparatus for continuously molding chocolate with inclusions, comprising: a substantially cylindrical rotary mold having an outer surface, at least one mold cavity on said outer surface, and an interior coolant cavity; conduits leading to and from said interior cavity for connecting said interior cavity with a coolant source; a liquid chocolate feeder for depositing liquid chocolate into said at least one mold cavity; a retaining/casting belt positioned to maintain said liquid chocolate in the mold cavity where the liquid chocolate solidifies; characterised in that the apparatus comprises: an inclusion feeder adapted to transport inclusions and communicating with said at least one mold cavity, so that at least one inclusion is deposited in the at least one mold cavity before the liquid chocolate is deposited into the mold cavity and prior to the liquid chocolate solidifying, wherein the inclusion feeder comprises a rotatable inclusion feeder drum positioned above the rotary mold, where the drum and mold are rotatable in opposite directions, such that inclusions may fall into each mold cavity by force of gravity prior to the liquid chocolate filling the mold. a substantially cylindrical rotary mold having an outer surface, at least one mold cavity on said outer surface, and an interior coolant cavity; conduits leading to and from said interior cavity for connecting said interior cavity with a coolant source; a liquid chocolate feeder for depositing liquid chocolate into said at least one mold cavity; a retaining/casting belt positioned to maintain said liquid chocolate in the mold cavity where the liquid chocolate solidifies; characterised in that the apparatus comprises: an inclusion feeder adapted to transport inclusions and communicating with said at least one mold cavity, so that at least one inclusion is deposited in the at least one mold cavity before the liquid chocolate is deposited into the mold cavity and prior to the liquid chocolate solidifying, wherein the inclusion feeder comprises a rotatable inclusion feeder drum positioned above the rotary mold, where the drum and mold are rotatable in opposite directions, such that inclusions may fall into each mold cavity by force of gravity prior to the liquid chocolate filling the mold. an inclusion feeder adapted to transport inclusions and communicating with said at least one mold cavity, so that at least one inclusion is deposited in the at least one mold cavity before the liquid chocolate is deposited into the mold cavity and prior to the liquid chocolate solidifying, wherein the inclusion feeder comprises a rotatable inclusion feeder drum positioned above the rotary mold, where the drum and mold are rotatable in opposite directions, such that inclusions may fall into each mold cavity by force of gravity prior to the liquid chocolate filling the mold.
A teat (110, 130, 150, 180) for use with a feeding bottle having a mouthpiece (114, 134, 154, 184) on which a baby sucks during feeding with one or more apertures (122, 144, 202) therein for the flow of milk out of the teat (110, 130, 150, 180), a main body (136, 156, 186) from which the mouthpiece (114, 134, 154, 184) extends, and an inner core (118, 138, 158, 188) disposed within the mouthpiece (114, 134, 154, 184) to define a fluid duct (120, 142, 170, 200) between the mouthpiece (114, 134, 154, 184) and the inner core (118, 138, 158, 188), the mouthpiece (114, 134, 154, 184) and the inner core (118, 138, 158, 188) being configured such that during feeding, the mouthpiece (114, 134, 154, 184) deforms characterized in that a majority of a perimeter surface of the inner core (118, 138, 158,188) lies against the mouthpiece (114, 134, 154, 184) and an elongate arced face or recess (115, 140, 168, 198) is formed in the inner core (118, 138, 158, 188) along the length of the inner core (118, 138, 158, 188), spaced from the mouthpiece (114, 134, 154, 184), wherein the duct (120, 142, 170, 200) is defined between said elongate arced face or recess (115, 140, 168, 198) and the mouthpiece (114, 134, 154, 184), such that the deformation of the mouthpiece (114, 134, 154, 184) makes a peristaltic feeding action possible which forces the milk along said duct (120, 142, 170, 200) and expels the milk through said one or more apertures (122, 144,202).
Method for controlling a rotary electric machine connected to an electrical network, in a case of load shedding, said machine comprising: - a plurality of phase windings; - a power circuit (12, 16), including a plurality of branches each formed from a switch bridge the switches of which are intended to be associated with said phase windings, which circuit is capable of supplying power to said electrical network under an output voltage (Vres) that is equal to a nominal voltage (Vn) in a nominal operating mode of said switch bridge; - an excitation winding through which an excitation current (Iexc) flows producing a magnetic flux in an excitation magnetic circuit; - an electronic control and regulation circuit driving said power circuit (12, 16) and controlling said excitation current (Iexc); and said method being of the type of those consisting of locking said switch bridge of at least one of said branches of said power circuit (12, 16) in a conducting state when said output voltage (Vres) exceeds a predetermined voltage threshold (Vs) that is higher than said nominal voltage (Vn), characterized in that said nominal operating mode of said switch bridge is re-established according to a criterion independent of said output voltage (Vres). - a plurality of phase windings; - a power circuit (12, 16), including a plurality of branches each formed from a switch bridge the switches of which are intended to be associated with said phase windings, which circuit is capable of supplying power to said electrical network under an output voltage (Vres) that is equal to a nominal voltage (Vn) in a nominal operating mode of said switch bridge; - an excitation winding through which an excitation current (Iexc) flows producing a magnetic flux in an excitation magnetic circuit; - an electronic control and regulation circuit driving said power circuit (12, 16) and controlling said excitation current (Iexc);
A metallocene catalyst based on a transition metal of groups 4 or 5 of the periodic table immobilized on a support modified with soluble hybrid silica, comprising: - at least one metallocene derived from a compound of formula 1: 2 - MQ 2 formula 1 wherein, M is a transition metal of groups 4 or 5; Q, which may be the same or different, comprises: halogen radical, aryl radical, alkyl radical containing from 1 to 5 carbon atoms or alkoxy radical containing from 1 to 5 carbon atoms; and L is a bulky ligand of the cyclopentadienyl, indenyl or fluorenyl type, substituted or not by hydrogen, alkyl, cycloalkyl, aryl, alkenyl, alkylaryl, arylalkyl or arylalkenyl, linked to the transition metal by bonding; - a hybrid soluble silica, prepared by a non-hydrolytic sol-gel process wherein a metal halide acts as catalyst of the sol-gel reaction; - an inorganic catalyst support modified with the hybrid soluble silica, wherein the hybrid soluble silica is obtained by means of the non-hydrolytic sol-gel route and has a structure consisting of siloxane groups (SiOSi), alkoxy groups and aliphatic organic groups, covalently bonded to the silicon atoms; and which is reacted with - at least one aluminum-containing organometallic reagent. - at least one metallocene derived from a compound of formula 1: 2 - MQ 2 formula 1 wherein, M is a transition metal of groups 4 or 5; Q, which may be the same or different, comprises: halogen radical, aryl radical, alkyl radical containing from 1 to 5 carbon atoms or alkoxy radical containing from 1 to 5 carbon atoms; and L is a bulky ligand of the cyclopentadienyl, indenyl or fluorenyl type, substituted or not by hydrogen, alkyl, cycloalkyl, aryl, alkenyl, alkylaryl, arylalkyl or arylalkenyl, linked to the transition metal by bonding; M is a transition metal of groups 4 or 5; Q, which may be the same or different, comprises: halogen radical, aryl radical, alkyl radical containing from 1 to 5 carbon atoms or alkoxy radical containing from 1 to 5 carbon atoms; and L is a bulky ligand of the cyclopentadienyl, indenyl or fluorenyl type, substituted or not by hydrogen, alkyl, cycloalkyl, aryl, alkenyl, alkylaryl, arylalkyl or arylalkenyl, linked to the transition metal by bonding; - a hybrid soluble silica, prepared by a non-hydrolytic sol-gel process wherein a metal halide acts as catalyst of the sol-gel reaction; - an inorganic catalyst support modified with the hybrid soluble silica, wherein the hybrid soluble silica is obtained by means of the non-hydrolytic sol-gel route and has a structure consisting of siloxane groups (SiOSi), alkoxy groups and aliphatic organic groups, covalently bonded to the silicon atoms; and which is reacted with - at least one aluminum-containing organometallic reagent.
A method of manufacturing an article of footwear from a flat pattern, the method comprising: cutting a first cut in a first material of the flat pattern, wherein the first material forms an upper portion and a coextensive footbed portion, and wherein the first cut forms an acute angle between an intersection (322, 324) of the upper portion and the footbed portion, the first material having a top surface and an opposite bottom surface, the first cut extending through the top surface and the bottom surface; coupling an overlay on the first material top surface, the overlay extending over the first cut such that the first cut is obscured on the first material top surface by the overlay wherein the overlay obscures the acute angle at said intersection (322, 324); and forming the flat pattern having the first material with the first cut and the overlay into a dimensional article of footwear configured to receive a foot, wherein the first material bottom surface is more interior to the dimensional article of footwear than the top surface. cutting a first cut in a first material of the flat pattern, wherein the first material forms an upper portion and a coextensive footbed portion, and wherein the first cut forms an acute angle between an intersection (322, 324) of the upper portion and the footbed portion, the first material having a top surface and an opposite bottom surface, the first cut extending through the top surface and the bottom surface; coupling an overlay on the first material top surface, the overlay extending over the first cut such that the first cut is obscured on the first material top surface by the overlay wherein the overlay obscures the acute angle at said intersection (322, 324); and forming the flat pattern having the first material with the first cut and the overlay into a dimensional article of footwear configured to receive a foot, wherein the first material bottom surface is more interior to the dimensional article of footwear than the top surface.
Particulate composition comprising (i) urea; and an additive comprising component (ii) and one or both of components (iii) and (vii): (ii) combination of polyethyleneimine and polyvinyl alcohol or combination of polyethyleneimine and polyvinylamine; (iii) at least one aliphatic C 2 -C 8 dialdehyde; (vii) at least one compound selected from the group of the aliphatic dicarboxylic acids and the salts and anhydrides thereof, the aliphatic tricarboxylic acids and the salts and anhydrides thereof, the aromatic dicarboxylic acids and the salts and anhydrides thereof, and the aldehyde acids and the salts and anhydrides thereof; and an additive comprising one or more of components (iv) to (v): (iv) sulfur: (v) ammonium sulfate; wherein the content by weight of component (i) is > 50% by weight and the content by weight of the sum of components (ii), (iii) and (vii) in the composition is < 1% by weight and the content by weight of the sum of components (iv) and (v) in the composition is < 50% by weight. (i) urea; (ii) combination of polyethyleneimine and polyvinyl alcohol or combination of polyethyleneimine and polyvinylamine; (iii) at least one aliphatic C 2 -C 8 dialdehyde; (vii) at least one compound selected from the group of the aliphatic dicarboxylic acids and the salts and anhydrides thereof, the aliphatic tricarboxylic acids and the salts and anhydrides thereof, the aromatic dicarboxylic acids and the salts and anhydrides thereof, and the aldehyde acids and the salts and anhydrides thereof; (iv) sulfur: (v) ammonium sulfate;