A distributed antenna system, comprising: a master unit configured to: receive at least one set of multiple input multiple output, MIMO, channel signals at original MIMO radio frequencies in a service provider frequency band from at least one signal source, the at least one set of the MIMO channel signals including at least a first MIMO channel signal at a first original MIMO radio frequency and a second MIMO channel signal at a second original MIMO radio frequency; generate a local oscillator signal; frequency convert the first MIMO channel signal having the first original MIMO radio frequency into a frequency converted first MIMO channel signal having a frequency different than the first original MIMO radio frequency using the local oscillator signal; maintain the second MIMO channel signal at the second original MIMO radio frequency; combine the frequency converted first MIMO channel signal, the second MIMO channel signal, and the local oscillator signal into a combined signal for transmission; an optical link operably coupled with the master unit; a remote unit communicatively coupled with the master unit via the optical link for receiving the combined signal from the master unit via the optical link, the remote unit further configured to process the combined signal to obtain the frequency converted first MIMO channel signal, the second MIMO channel signal, and the local oscillator signal; at least one extension unit in communication with the remote unit, wherein the at least one extension unit includes conversion circuitry and is configured to receive the frequency converted first MIMO channel signal and the local oscillator signal from the remote unit and to frequency convert the frequency converted first MIMO channel signal from the frequency different than the first original MIMO radio frequency back to the first original MIMO radio frequency for transmission over at least one antenna (44a, 44b, 132a, 132b, 216a, 216b, 216c, 216d). receive at least one set of multiple input multiple output, MIMO, channel signals at original MIMO radio frequencies in a service provider frequency band from at least one signal source, the at least one set of the MIMO channel signals including at least a first MIMO channel signal at a first original MIMO radio frequency and a second MIMO channel signal at a second original MIMO radio frequency; generate a local oscillator signal; frequency convert the first MIMO channel signal having the first original MIMO radio frequency into a frequency converted first MIMO channel signal having a frequency different than the first original MIMO radio frequency using the local oscillator signal; maintain the second MIMO channel signal at the second original MIMO radio frequency; combine the frequency converted first MIMO channel signal, the second MIMO channel signal, and the local oscillator signal into a combined signal for transmission; an optical link operably coupled with the master unit; a remote unit communicatively coupled with the master unit via the optical link for receiving the combined signal from the master unit via the optical link, the remote unit further configured to process the combined signal to obtain the frequency converted first MIMO channel signal, the second MIMO channel signal, and the local oscillator signal; at least one extension unit in communication with the remote unit, wherein the at least one extension unit includes conversion circuitry and is configured to receive the frequency converted first MIMO channel signal and the local oscillator signal from the remote unit and to frequency convert the frequency converted first MIMO channel signal from the frequency different than the first original MIMO radio frequency back to the first original MIMO radio frequency for transmission over at least one antenna (44a, 44b, 132a, 132b, 216a, 216b, 216c, 216d).