A compound having formula: where X, Y and Z are H, F, or Cl; R 1 is OR, where R is hydrogen or a group selected from straight or branched C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 6 cycloalkyl, heterocyclyl, CF 3, CCl 3, and aryl in positions 2, 3 or 4; R 2 is OH, alkoxy, aryloxy, CH 2 OR (where R is H, linear or branched aryl, cycloalkyl or alkyl), CH 2 NR'R" (where R' and R" are independently H, linear or branched aryl, cycloalkyl or alkyl), CHO, OCOW (where W is linear or branched aryl or alkyl or C-(halogen) 3), CONR'R" (where R' and R" independently are H, alkyl, cycloalkyl or aryl), COOR (where R is H, alkyl, cycloalkyl or aryl), CH 2 NHSO 2 R (where R is H, alkyl, cycloalkyl or aryl), Cl, Br, F, CH 2 - N -benzimidazole, CONHNR'R" (where R' and R" independently are H, alkyl, cycloalkyl or aryl), NRCOOR' (where R and R' are independently H, alkyl, cycloalkyl or aryl), NH 2, NR'R" (where R' and R" independently are alkyl, cycloalkyl or aryl), NHCOR (where R is H, alkyl, cycloalkyl or aryl), nitro, OCH 2 CH 2 -heterocyclyl, OCOR (where R is H, alkyl, cycloalkyl or aryl), OCONR'R" (where R' and R" are independently H, alkyl, cycloalkyl or aryl), OCOOR (where R is H, alkyl, cycloalkyl or aryl), NHCOOCH 2 C-halo 3, NRCONR'R" (where R, R' and R" independently are H, alkyl, cycloalkyl or aryl), NHSO 2 R (where R is H, alkyl, cycloalkyl or aryl), NHSO 2 NR'R" (where R' and R" independently are H, alkyl, cycloalkyl or aryl), and R 3 is OH, alkoxy, aryloxy, NR'R" (where R' and R" are H), NHCOR (where R is H, alkyl, cycloalkyl or aryl), and_CONR'R" (where R' and R" independently are H, alkyl, cycloalkyl or aryl). where X, Y and Z are H, F, or Cl; R 1 is OR, where R is hydrogen or a group selected from straight or branched C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 6 cycloalkyl, heterocyclyl, CF 3, CCl 3, and aryl in positions 2, 3 or 4; R 2 is OH, alkoxy, aryloxy, CH 2 OR (where R is H, linear or branched aryl, cycloalkyl or alkyl), CH 2 NR'R" (where R' and R" are independently H, linear or branched aryl, cycloalkyl or alkyl), CHO, OCOW (where W is linear or branched aryl or alkyl or C-(halogen) 3), CONR'R" (where R' and R" independently are H, alkyl, cycloalkyl or aryl), COOR (where R is H, alkyl, cycloalkyl or aryl), CH 2 NHSO 2 R (where R is H, alkyl, cycloalkyl or aryl), Cl, Br, F, CH 2 - N -benzimidazole, CONHNR'R" (where R' and R" independently are H, alkyl, cycloalkyl or aryl), NRCOOR' (where R and R' are independently H, alkyl, cycloalkyl or aryl), NH 2, NR'R" (where R' and R" independently are alkyl, cycloalkyl or aryl), NHCOR (where R is H, alkyl, cycloalkyl or aryl), nitro, OCH 2 CH 2 -heterocyclyl, OCOR (where R is H, alkyl, cycloalkyl or aryl), OCONR'R" (where R' and R" are independently H, alkyl, cycloalkyl or aryl), OCOOR (where R is H, alkyl, cycloalkyl or aryl), NHCOOCH 2 C-halo 3, NRCONR'R" (where R, R' and R" independently are H, alkyl, cycloalkyl or aryl), NHSO 2 R (where R is H, alkyl, cycloalkyl or aryl), NHSO 2 NR'R" (where R' and R" independently are H, alkyl, cycloalkyl or aryl), and R 3 is OH, alkoxy, aryloxy, NR'R" (where R' and R" are H), NHCOR (where R is H, alkyl, cycloalkyl or aryl), and_CONR'R" (where R' and R" independently are H, alkyl, cycloalkyl or aryl).