A closure assembly (14, 110) for a container defining an interior volume, an opening into said interior volume, and a sealing surface bordering said opening, said closure assembly comprising: a closure, including an inner surface, said closure being attachable over a container opening; an impermeable inner seal comprising a metallic foil, including a first surface for temporary engagement with a container sealing surface and a second, opposed surface; a radio frequency identification tag (25, 46, 64, 80, 120) including a microprocessor electromagnetically coupled with an antenna (24, 52) for selectively receiving, storing, and transmitting digitized information; characterized by: an isolation liner (40, 42, 58) or an isolation pad disposed between the microprocessor and said first surface or said second surface to electromagnetically isolate said microprocessor from said metallic foil; wherein said impermeable inner seal can prevent migration of a substance between a container interior volume and an exterior of a container when said impermeable inner seal is engaged with a container sealing surface; and wherein said radio frequency identification tag (25, 46, 64, 80, 120) is included in said closure assembly, contained within a container interior volume, mounted to an exterior surface of a container, or incorporated into said impermeable inner seal, without said closure assembly electromagnetically interfering with said receiving, storing, or transmitting of said digitized information. a closure, including an inner surface, said closure being attachable over a container opening; an impermeable inner seal comprising a metallic foil, including a first surface for temporary engagement with a container sealing surface and a second, opposed surface; a radio frequency identification tag (25, 46, 64, 80, 120) including a microprocessor electromagnetically coupled with an antenna (24, 52) for selectively receiving, storing, and transmitting digitized information; characterized by: an isolation liner (40, 42, 58) or an isolation pad disposed between the microprocessor and said first surface or said second surface to electromagnetically isolate said microprocessor from said metallic foil; wherein said impermeable inner seal can prevent migration of a substance between a container interior volume and an exterior of a container when said impermeable inner seal is engaged with a container sealing surface; and wherein said radio frequency identification tag (25, 46, 64, 80, 120) is included in said closure assembly, contained within a container interior volume, mounted to an exterior surface of a container, or incorporated into said impermeable inner seal, without said closure assembly electromagnetically interfering with said receiving, storing, or transmitting of said digitized information. an isolation liner (40, 42, 58) or an isolation pad disposed between the microprocessor and said first surface or said second surface to electromagnetically isolate said microprocessor from said metallic foil; wherein said impermeable inner seal can prevent migration of a substance between a container interior volume and an exterior of a container when said impermeable inner seal is engaged with a container sealing surface; and wherein said radio frequency identification tag (25, 46, 64, 80, 120) is included in said closure assembly, contained within a container interior volume, mounted to an exterior surface of a container, or incorporated into said impermeable inner seal, without said closure assembly electromagnetically interfering with said receiving, storing, or transmitting of said digitized information.