Device for automatically fixing and/or embedding a sample in a patient, comprising - a sample region with a sample space, in which the sample space is embodied to receive a sample; - a cover, which is connected to the sample region and is embodied to close the sample space after the sample has been introduced; - a substance region, which comprises at least one first and one second compartment (K1, K2), wherein the first compartment is embodied to receive at least one first substance and the second compartment is embodied to receive at least one second substance, wherein the at least one first substance and the at least one second substance differ and are used to fix and/or embed the sample of the patient; - a fluidic region, which connects the first compartment with the sample space and the second compartment with the sample space so that the at least one first substance can be routed from the first compartment via a first channel and the at least one second substance can be routed from the second compartment via a second channel into the sample space, wherein the first channel comprises at least one first and the second channel comprises at least one second valve; - a collection region with a collection compartment, in which the collection compartment is embodied to collect at least one first replaced substance, at least one second replaced substance, the at least one first substance and/or the at least one second substance, wherein the collection compartment is connected to the sample space with at least one collection channel, which comprises at least one collection valve, and - a control region with at least one control device, which is embodied to control at least the at least one first valve, the at least one second valve and the at least one collection valve; characterised in that the device has an overall volume which corresponds at most to forty times the volume of the sample space, wherein the sample space has a volume of less than 200 cm 3. - a sample region with a sample space, in which the sample space is embodied to receive a sample; - a cover, which is connected to the sample region and is embodied to close the sample space after the sample has been introduced; - a substance region, which comprises at least one first and one second compartment (K1, K2), wherein the first compartment is embodied to receive at least one first substance and the second compartment is embodied to receive at least one second substance, wherein the at least one first substance and the at least one second substance differ and are used to fix and/or embed the sample of the patient; - a fluidic region, which connects the first compartment with the sample space and the second compartment with the sample space so that the at least one first substance can be routed from the first compartment via a first channel and the at least one second substance can be routed from the second compartment via a second channel into the sample space, wherein the first channel comprises at least one first and the second channel comprises at least one second valve; - a collection region with a collection compartment, in which the collection compartment is embodied to collect at least one first replaced substance, at least one second replaced substance, the at least one first substance and/or the at least one second substance, wherein the collection compartment is connected to the sample space with at least one collection channel, which comprises at least one collection valve, and - a control region with at least one control device, which is embodied to control at least the at least one first valve, the at least one second valve and the at least one collection valve; characterised in that the device has an overall volume which corresponds at most to forty times the volume of the sample space, wherein the sample space has a volume of less than 200 cm 3.