Device for measuring a blood parameter, preferably related to the presence or concentration of oxygen in blood, comprising: - a box body, - a coupling portion associated to the box body and comprising at least one coupling element (8, 9), the coupling portion being configured to feature: o a coupled configuration wherein it is coupled to a container by said at least one coupling element (8, 9), o a decoupled configuration wherein it is not coupled to a container, - a container, for example a tubular element, apt to contain blood and/or in which blood can flow, the container being configured to be coupled to said coupling portion, - a photosensitive element associated to the container and apt to respond, at the end of an excitation to which it is subjected when it is in contact with blood, with a light response, the light response providing a luminescence decay curve, in operative conditions the photosensitive element being in contact with blood, - an excitation member housed inside the box body and configured to excite said photosensitive element by a series of excitation pulses, - a photodetector housed inside the box body and configured to detect, in operative conditions of the device, a plurality of light responses of the photosensitive element corresponding to the series of excitation pulses, the light responses providing luminescence decay curves, - a temperature sensor housed inside the box body and configured to detect the temperature of blood, - a control unit housed inside the box body and configured to perform the following operations: o receiving, for each of at least two time windows (t1, t2, t3, t4, t5, tN-1, tN) in which each luminescence curve is analyzed, one or more light response analog information regarding the luminescence decay curve, o converting the light response analog information, detected at at least two time windows (t1, t2, t3, t4, t5, tN-1, tN) for each light response, into light response digital data, o processing said light response digital data and the actual temperature value of blood by considering a plurality of data of previous measures of said blood parameter performed during previous training, o determining, as a result of the processing operation, at least one value of said blood parameter. - a box body, - a coupling portion associated to the box body and comprising at least one coupling element (8, 9), the coupling portion being configured to feature: o a coupled configuration wherein it is coupled to a container by said at least one coupling element (8, 9), o a decoupled configuration wherein it is not coupled to a container, o a coupled configuration wherein it is coupled to a container by said at least one coupling element (8, 9), o a decoupled configuration wherein it is not coupled to a container, - a container, for example a tubular element, apt to contain blood and/or in which blood can flow, the container being configured to be coupled to said coupling portion, - a photosensitive element associated to the container and apt to respond, at the end of an excitation to which it is subjected when it is in contact with blood, with a light response, the light response providing a luminescence decay curve, in operative conditions the photosensitive element being in contact with blood, - an excitation member housed inside the box body and configured to excite said photosensitive element by a series of excitation pulses, - a photodetector housed inside the box body and configured to detect, in operative conditions of the device, a plurality of light responses of the photosensitive element corresponding to the series of excitation pulses, the light responses providing luminescence decay curves, - a temperature sensor housed inside the box body and configured to detect the temperature of blood, - a control unit housed inside the box body and configured to perform the following operations: o receiving, for each of at least two time windows (t1, t2, t3, t4, t5, tN-1, tN) in which each luminescence curve is analyzed, one or more light response analog information regarding the luminescence decay curve, o converting the light response analog information, detected at at least two time windows (t1, t2, t3, t4, t5, tN-1, tN) for each light response, into light response digital data, o processing said light response digital data and the actual temperature value of blood by considering a plurality of data of previous measures of said blood parameter performed during previous training, o determining, as a result of the processing operation, at least one value of said blood parameter. o receiving, for each of at least two time windows (t1, t2, t3, t4, t5, tN-1, tN) in which each luminescence curve is analyzed, one or more light response analog information regarding the luminescence decay curve, o converting the light response analog information, detected at at least two time windows (t1, t2, t3, t4, t5, tN-1, tN) for each light response, into light response digital data, o processing said light response digital data and the actual temperature value of blood by considering a plurality of data of previous measures of said blood parameter performed during previous training, o determining, as a result of the processing operation, at least one value of said blood parameter.