mhurhangee/ep-ind-claims huggingface dataset:
A hydroxyindole carboxylic acid, the hydroxyindole carboxylic acid comprising formula: wherein L 1 is selected from the group consisting of a single bond, -(C 1-6 alkyl)-, -(C 2-6 alkenyl)-, -(C 0-6 alkyl)-(C 3-6 cycloalkyl)-(C 0-6 alkyl)-, o-phenyl, m-phenyl, p-phenyl, a 3-7 member single aromatic or aliphatic ring, an unsubstituted or substituted fused 5-12 member aromatic or aliphatic ring system, wherein the substitution is selected from the group consisting of nitrogen, oxygen and sulfur; L 2 is selected from the group consisting of a bond, and wherein n is 0-3; and R 1 = NRaRb, wherein Ra or Rb can each independently be selected from the group consisting of hydrogen, unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl, unsubstituted or substituted heterocyclyl, unsubstituted or substituted aryl, unsubstituted or substituted heteroaryl, and unsubstituted or substituted fused 5-12 member aromatic or aliphatic ring system, wherein the substitution on the fused 5-12 member aromatic or aliphatic ring system is selected from the group consisting of nitrogen, oxygen and sulfur. wherein L 1 is selected from the group consisting of a single bond, -(C 1-6 alkyl)-, -(C 2-6 alkenyl)-, -(C 0-6 alkyl)-(C 3-6 cycloalkyl)-(C 0-6 alkyl)-, o-phenyl, m-phenyl, p-phenyl, a 3-7 member single aromatic or aliphatic ring, an unsubstituted or substituted fused 5-12 member aromatic or aliphatic ring system, wherein the substitution is selected from the group consisting of nitrogen, oxygen and sulfur; L 2 is selected from the group consisting of a bond, and wherein n is 0-3; and R 1 = NRaRb, wherein Ra or Rb can each independently be selected from the group consisting of hydrogen, unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl, unsubstituted or substituted heterocyclyl, unsubstituted or substituted aryl, unsubstituted or substituted heteroaryl, and unsubstituted or substituted fused 5-12 member aromatic or aliphatic ring system, wherein the substitution on the fused 5-12 member aromatic or aliphatic ring system is selected from the group consisting of nitrogen, oxygen and sulfur.
A tip assembly, comprising a proximal end, comprising a Y fitting, the Y fitting comprising a first proximal end; a second proximal end; a distal end; a first fluid channel extending from the first proximal end to the distal end; and a second fluid channel extending from the second proximal end to the distal end; a distal end; a mixing nozzle, comprising a proximal end, comprising a fluid inlet; a distal end, comprising a fluid outlet, wherein the distal end of the mixing nozzle corresponds to the distal end of the tip assembly; and a mixing chamber disposed between and in fluid communication with the fluid inlet and the fluid outlet; a tube extending from the distal end of the Y fitting to the proximal end of the mixing nozzle; a first cannula, disposed within and extending along substantially the entire length of the tube, in fluid communication with the first fluid channel of the Y fitting and the fluid inlet of the mixing nozzle; and a second cannula, disposed within and extending along substantially the entire length of the tube, in fluid communication with the second fluid channel of the Y fitting and the fluid inlet of the mixing nozzle; wherein the tube, the first cannula, and the second cannula are flexible; characterised in that the tip assembly further comprises a tubing adapter to receive the distal end of the Y fitting and a proximal end of the tube, in that the first cannula and the second cannula have an inside diameter of about 0.76 mm to about 1.27 mm, and in that the first cannula and the second cannula are identical in length and inside diameter. a first proximal end; a second proximal end; a distal end; a first fluid channel extending from the first proximal end to the distal end; and a second fluid channel extending from the second proximal end to the distal end; a proximal end, comprising a fluid inlet; a distal end, comprising a fluid outlet, wherein the distal end of the mixing nozzle corresponds to the distal end of the tip assembly; and a mixing chamber disposed between and in fluid communication with the fluid inlet and the fluid outlet;
Process for the preparation of a sugar product from lignocellulosic material, comprising the following steps: a) optionally, pretreatment of the lignocellulosic material; b) optionally, washing of the optionally pretreated lignocellulosic material; c) fed-batch addition of the optionally washed and/or optionally pretreated lignocellulosic material to a first container that comprises an enzyme composition comprising at least two cellulases; d) enzymatic hydrolysis of the optionally washed and/or optionally pretreated lignocellulosic material in the first container using the enzyme composition comprising at least two cellulases to liquefy the lignocellulosic material; e) addition of the liquefied lignocellulosic material to a second container; f) enzymatic hydrolysis of the liquefied lignocellulosic material in the second container using an enzyme composition comprising at least two cellulases to obtain a sugar product; and g) optionally, recovery of the sugar product, wherein oxygen is added to the first container and/or second container and wherein the feeding step starts by adding lignocellulosic material to a container wherein an enzyme composition is present and wherein enzymes used in the hydrolysis process are present at the start of the feeding step. a) optionally, pretreatment of the lignocellulosic material; b) optionally, washing of the optionally pretreated lignocellulosic material; c) fed-batch addition of the optionally washed and/or optionally pretreated lignocellulosic material to a first container that comprises an enzyme composition comprising at least two cellulases; d) enzymatic hydrolysis of the optionally washed and/or optionally pretreated lignocellulosic material in the first container using the enzyme composition comprising at least two cellulases to liquefy the lignocellulosic material; e) addition of the liquefied lignocellulosic material to a second container; f) enzymatic hydrolysis of the liquefied lignocellulosic material in the second container using an enzyme composition comprising at least two cellulases to obtain a sugar product; and g) optionally, recovery of the sugar product, wherein oxygen is added to the first container and/or second container and wherein the feeding step starts by adding lignocellulosic material to a container wherein an enzyme composition is present and wherein enzymes used in the hydrolysis process are present at the start of the feeding step.
Panel light, comprising: an optical element panel substantially extending in a plane and having a front side, a rear side and a circumferential side edge extending between the front side and the rear side, a light source to emit light via the optical element panel for light output of the panel light, an electronic module to run the light source, and a luminaire housing for carrying the optical element panel, wherein an opening penetrates the optical element panel to connect the front side and the rear side wherein the luminaire housing comprises a base portion covering the rear side of the optical element panel, wherein the base portion is in flat contact with the rear side of the optical element panel and extends over the whole rear side to thus completely cover and support the optical element panel at its rear side, and wherein the base portion comprises a second opening being coaxially arranged with the opening of the optical element panel to form a through hole designed to receive at least part of a functional component. an optical element panel substantially extending in a plane and having a front side, a rear side and a circumferential side edge extending between the front side and the rear side, a light source to emit light via the optical element panel for light output of the panel light, an electronic module to run the light source, and a luminaire housing for carrying the optical element panel, wherein an opening penetrates the optical element panel to connect the front side and the rear side wherein the luminaire housing comprises a base portion covering the rear side of the optical element panel, wherein the base portion is in flat contact with the rear side of the optical element panel and extends over the whole rear side to thus completely cover and support the optical element panel at its rear side, and wherein the base portion comprises a second opening being coaxially arranged with the opening of the optical element panel to form a through hole designed to receive at least part of a functional component.
A device for mounting a slider to actuate closure profiles (P 1, P 2), in particular for a closure assembly equipping a bag, which comprises a base, two flanges (11,12) and means adapted to urge the said closure profiles (P 1, P 2) respectively to draw together or to draw apart depending on the direction of travel of the slider along the profiles (P 1, P 2), to move the profiles (P 1, P 2) between an engaged closed position and a separated open position, on a bag with mating closure profiles (P 1, P 2) or on an assembly of mating closure profiles (P 1, P 2), this device comprising at least one retaining clamp to hold the profiles (P 1, P 2) in stable position, and means to push a slider towards means for provisionally drawing apart said flanges (11, 12) of the slider for the purpose of causing it to cooperate with the said profiles (P 1, P 2) in stable position, these drawing-apart means comprising cam paths with rising slope, characterized by the fact that the said means are composed of retractable cams which, in a first non-retracted position, interact with said slider so that during the travel thereof the inner face (110, 120) of its flanges (11, 12) comes into contact with the cam paths to draw them gradually away from each other and which, in a second retracted position, no longer interact with the said slider so that the said flanges (11, 12) draw close to one another, the changeover from the first to the second position taking place by contact of the base of said slider with the said cams, during the movement of said slider.
An apparatus for producing reinforcing means usable for constructing a building, and which take the form of first upper and second lower reinforcing means, defined by a respective metal mesh; said reinforcing means comprise respective longitudinal members (11 a, 13a), which take the form of respective wires or rods, and respective transverse members (11b, 13b), which take the form of associated wires or rods; the apparatus comprises positioning means (38, 40) for positioning the transverse reinforcing members in line with the joining zone to the longitudinal reinforcing members (11 a), characterised in that said positioning means comprise first positioning means being capable of moving respective transverse members upwards to position them below corresponding longitudinal reinforcing members of said first upper reinforcing means and second positioning means being capable of moving respective transverse members downwards under gravity to position them above corresponding longitudinal reinforcing members of said second lower reinforcing means, said first positioning means and second positioning means for the transverse members are arranged between the first and second reinforcing means(11, 13).
A peptide of less than 30 amino acids, which comprises the RETEV motif, wherein the amino acid sequence of said peptide comprises at least one of SEQ ID NOs: 1-3, 5 and 7, and wherein said peptide has an affinity for the PDZ of PTPN4 that is lower than 4 microM.
A method for improving plasma uniformity in a plasma etching process, the method comprising: placing a substrate in a vacuum chamber comprising a dielectric cylinder as its chamber wall, J Z said vacuum chamber having a mechanically adjustable helical RF coil positioned outside and in proximity to said dielectric cylinder; subjecting the substrate to an inductively coupled plasma etch process within said vacuum chamber; characterized in mechanically adjusting the position of said mechanically adjustable helical RF coil in an "X" direction and in a "Y" direction relative to said dielectric cylinder through a mechanism, said mechanism being attached to said mechanically adjustable helical RF coil and removing the substrate from the vacuum chamber.
A composition for intravitreal administration of a therapeutic protein, characterized in that it comprises a therapeutic protein and a polyamidoamine dendrimeric polycation combined electrostatically with the therapeutic protein, wherein the therapeutic protein is neurotrophin-4 (NT-4) and the polyamidoamine dendrimeric polycation is a PAMAM dendrimer, preferably PAMAM G 6.0.
A Cardio-Pulmonary Resuscitation ("CPR") machine configured to perform chest compressions on a chest of a patient, the chest having a resting height relative to a reference level, the resting height measured when no chest compressions are being performed, the CPR machine comprising: a compression mechanism; a chest-lifting device configured to lift the chest; and a driver system configured to drive the compression mechanism and the chest-lifting device according to a motion-time profile so as to cause the chest-lifting device to lift the chest a first distance from the resting height and the chest-lifting device to lift the chest a second distance from the resting height greater than the first distance after lifting the chest to the first distance. a compression mechanism; a chest-lifting device configured to lift the chest; and a driver system configured to drive the compression mechanism and the chest-lifting device according to a motion-time profile so as to cause the chest-lifting device to lift the chest a first distance from the resting height and the chest-lifting device to lift the chest a second distance from the resting height greater than the first distance after lifting the chest to the first distance.
Sensor arrangement which has a sensor array and a substrate, wherein the sensor array is monolithically integrated in and/or on the substrate, having at least three electrodes, wherein the plurality of the at least three electrodes are designed as biosensor arrangements for detection of biomolecules, and having a switching unit, which is designed in such a manner that, by means of the switching unit, at least one of the at least three electrodes can be selectively connected as a working electrode (WE, 210) which is coupled to an electrolyte solution of an electrolytic analyte and that at least two of the electrodes of the at least three electrodes can be selectively connected as an opposing electrode, and wherein the at least three electrodes are designed in such a manner that sensor events take place at one electrode, which is connected as a working electrode (WE, 210), of the at least three electrodes in the electrolyte solution when in the presence of the electrolytic analyte, characterized by a control circuit which is designed to drive, select and/or read the at least three electrodes or some of the at least three electrodes, to provide the opposing electrode by interconnection of electrodes of the sensor array which are not used as working electrodes.
Pipe connection comprising a pipe, a ring, a flange and fastening means, the ring which projects radially beyond the pipe being fastened to the end of the pipe, and the flange being configured to bear against a bearing face of the ring, and the fastening means fixing the flange for fastening the pipe end, and the pipe end having, on its outer circumference, and the ring having, on its inner circumference, in each case one threaded section (16, 14), and in that the ring is screwed by way of the threaded section onto the threaded section of the pipe end, characterized in that the pipe connection has a seal carrier which is of hollow-cylindrical configuration, has at least one groove for receiving a sealing ring, and is arranged between the pipe end and a connector face which lies opposite the pipe end, and in that an internal radius of the seal carrier corresponds to an internal radius of the pipe, and an external radius of the seal carrier corresponds to an external radius of the ring.
A drive device for a movable furniture part, comprising a retracting device for retracting the movable furniture part from an open position into a closed position, said retracting device having - a housing, - a guide path which is formed in the housing and which comprises a retaining section, - a retracting slide which can be moved in the guide path relative to the housing and can be locked in the retaining section and - a retracting force storage means which urges the retracting slide, wherein the retracting slide can be moved along the guide path between a first end position, which corresponds to the retaining section, and a second end position, which corresponds to the closed end position, characterized in that the distance of the end positions (E1, E2) from each other along the guide path can be changed, wherein the drive device comprises limit stops or bordering elements and the distance of the end positions (E1, E2) is adjusted by the limit stops or bordering elements, or wherein the housing has a base part and a slide part which is movable relative to the base part between at least a first state and a second state. - a housing, - a guide path which is formed in the housing and which comprises a retaining section, - a retracting slide which can be moved in the guide path relative to the housing and can be locked in the retaining section and - a retracting force storage means which urges the retracting slide,
Device for performing at least one medical function on a user, wherein the device has at least one medical functional element that is designed to perform the medical function, wherein the medical function is selected from a diagnostic, a therapeutic and a surgical function, wherein the device has at least one evaluation and control part, wherein the evaluation and control part has at least one actuation component for controlling the medical function, wherein the evaluation and control part has at least one casing and at least one battery receptacle, wherein the battery receptacle comprises at least one electrical energy reservoir, more particularly at least one battery, wherein the battery receptacle is designed to be opened irreversibly by the user for removing the energy reservoir, wherein the battery receptacle has a battery-receptacle casing, wherein the battery-receptacle casing and the casing are interconnected, wherein the connection can be irreversibly detached by the user, wherein the casing, more particularly the disposable casing, has at least one predetermined breaking point, wherein the casing is deformed when the battery-receptacle casing is detached from the casing.
A method for protecting a surface of an article from sulfate corrosion resulting from exposure to a sulfate containing material at an elevated temperature, comprising coating the surface with a nickel based material to form an anti-corrosion coating, the nickel based material comprising NiO, a spinel of formulation AB 2 O 4, or a combination thereof, wherein A comprises nickel, and B comprises iron or a combination of manganese and a B site dopant.
An individually pocketed coil spring for use in a bedding or seating product, said individually pocketed coil spring comprising: a coil spring having an upper end and a lower end, a casing for ming a pocket enclosing said coil spring; and a cushioning pad located above said upper end of the coil spring; wherein the casing provides a first compartment enclosing the coil spring, and a second compartment enclosing the cushioning pad, said first and second compartment (21, 22) being separated from each other. a coil spring having an upper end and a lower end, a casing for ming a pocket enclosing said coil spring; and a cushioning pad located above said upper end of the coil spring; wherein the casing provides a first compartment enclosing the coil spring, and a second compartment enclosing the cushioning pad, said first and second compartment (21, 22) being separated from each other.
Method for directing communication traffic to and from a communication unit (400, A4, A6, A7, A8, A9) within an application control system, wherein the application control system comprises a network, the network comprising a plurality of application control components (301, L1-L34, Tx1-Tx3) and data-forwarding devices (d1-d8) for forwarding data to the application control components, the application control components being capable of transmitting data to the communication unit using light waves, the method comprising: determining the positions of the application control components (301, L1-L34, Tx1-Tx3) within the application control system; determining first position information of a first communication unit (400, A4, A6, A7, A8, A9) within the application control system at a first instant; computing an area of interest for the first communication unit based on at least the first position information; and identifying a first subgroup of one or more application control components from the plurality of application control components located within the area of interest of the first communication unit; characterized in that the method comprises: programming data paths through the application control system by programming the data-forwarding devices (d1-d8) to forward data to the first communication unit (400, A4, A6, A7, A8, A9) via a selected path in the network and to communicate data with the first communication unit (400, A4, A6, A8, A9) using the identified subgroup of application control components and temporarily assigning a light channel for wireless optical communication to the first communication unit for delivering data addressed to the first communication unit (400, A4, A6, A8, A9) using the assigned light channel. determining the positions of the application control components (301, L1-L34, Tx1-Tx3) within the application control system; determining first position information of a first communication unit (400, A4, A6, A7, A8, A9) within the application control system at a first instant; computing an area of interest for the first communication unit based on at least the first position information; and identifying a first subgroup of one or more application control components from the plurality of application control components located within the area of interest of the first communication unit; programming data paths through the application control system by programming the data-forwarding devices (d1-d8) to forward data to the first communication unit (400, A4, A6, A7, A8, A9) via a selected path in the network and to communicate data with the first communication unit (400, A4, A6, A8, A9) using the identified subgroup of application control components and temporarily assigning a light channel for wireless optical communication to the first communication unit for delivering data addressed to the first communication unit (400, A4, A6, A8, A9) using the assigned light channel.
A closed suture loop comprising: a tubular braided length of filaments defining a hollow conduit; characterised in that the closed suture loop further comprises a non-braided length of the filaments, where the braided length of the filaments and the non-braided length of the filaments form the closed suture loop. a tubular braided length of filaments defining a hollow conduit; characterised in that the closed suture loop further comprises a non-braided length of the filaments, where the braided length of the filaments and the non-braided length of the filaments form the closed suture loop.