A compound of Formula I or a salt thereof: Q 2 -X-Y-CHR 3 -CHR 4 -Q 1 wherein: Q 1 is substituted phenyl, with up to 5 substituents selected from the group consisting of: fluoro; bromo; nitro; -NR 10 R 11; aroylamino; cyano; carboxamido; trifluoromethyl; -O-R 10; [-N(-R 1)-(CH 2) m -C(-R 5)(-R 6)-(CH 2) n -COOR 7] z; and a C 1 -C 10 saturated or unsaturated, straight or branched, cyclic or acyclic, chiral or achiral hydrocarbyl group, wherein optionally at least one carbon atom of the hydrocarbyl group is replaced by -N(-R 1)-, -O- or -S-; wherein Q 1 has at least one substituent selected from the group consisting of -O-R 10 and fluoro; Q 2 is substituted phenyl, with up to 5 substituents selected from the group consisting of: fluoro; chloro; nitro; -NR 10 R 11; aroylamino; cyano; carboxy; carboxamido; trifluoromethyl; -O-SO 2 -OH; -O-P(=O)(OR 8) 2; -O-R 10; [-N(-R 9)-(CH 2) m -C(-R 5)(-R 6)-(CH 2) n -COOR 7] z; and a C 1 -C 10 saturated or unsaturated, straight or branched, cyclic or acyclic, chiral or achiral hydrocarbyl group, wherein optionally at least one carbon atom of the hydrocarbyl group is replaced by -N(-R 1)-, -O- or -S-; wherein at least the 4-position of both Q 1 and Q 2 is substituted, and one of Q 1 and Q 2 is substituted with a substituent other than unsubstituted phenyl; X is -CH 2 -; Y is -S(=O) 2 -; R 1 is selected from the group consisting of H and a C 1 -C 10 saturated or unsaturated, straight or branched, cyclic or acyclic, chiral or achiral hydrocarbyl group, wherein optionally at least one carbon atom of the hydrocarbyl group is replaced by -N(-R 1)-, -O- or -S-; R 3 and R 4 are each H; R 5 and R 6 are each independently selected from the group consisting of H; halo; and C 1 -C 10 saturated or unsaturated, straight or branched, cyclic or acyclic, chiral or achiral hydrocarbyl group, optionally substituted with one or more of halogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, hydroxy, carboxy, carboxamido, amino, (C 1 -C 6) alkyl, (C 1 -C 6) dialkyl amino, or acylamino; or R 5 and R 6 may combine to form a saturated or unsaturated carbocyclic ring with from 3 to 6 carbon atoms, wherein one or more carbon atoms is optionally replaced with -N(-R 1)-, -O-, or -S-; R 7 is selected from the group consisting of H; and a C 1 -C 10 saturated or unsaturated, straight or branched, cyclic or acyclic, chiral or achiral hydrocarbyl group; and an inorganic cation or an organic cation to form a salt; R 8 is selected from the group consisting of H and (C 1 -C 7) hydrocarbyl; R 9 is selected from the group consisting of H and -(CH 2) m -C(-R 5)(-R 6)-(CH 2) n -COOR 7; R 10 is selected from the group consisting of H, branched or unbranched (C 1 -C 6)alkyl, and (C 2 -C 8)acyl; R 11 is selected from the group consisting of H, branched or unbranched (C 1 -C 6)alkyl, and (C 2 -C 8)acyl; m and n are each independently 0-2; and z is 1-2. Q 1 is substituted phenyl, with up to 5 substituents selected from the group consisting of: fluoro; bromo; nitro; -NR 10 R 11; aroylamino; cyano; carboxamido; trifluoromethyl; -O-R 10; [-N(-R 1)-(CH 2) m -C(-R 5)(-R 6)-(CH 2) n -COOR 7] z; and a C 1 -C 10 saturated or unsaturated, straight or branched, cyclic or acyclic, chiral or achiral hydrocarbyl group, wherein optionally at least one carbon atom of the hydrocarbyl group is replaced by -N(-R 1)-, -O- or -S-; wherein Q 1 has at least one substituent selected from the group consisting of -O-R 10 and fluoro; Q 2 is substituted phenyl, with up to 5 substituents selected from the group consisting of: fluoro; chloro; nitro; -NR 10 R 11; aroylamino; cyano; carboxy; carboxamido; trifluoromethyl; -O-SO 2 -OH; -O-P(=O)(OR 8) 2; -O-R 10; [-N(-R 9)-(CH 2) m -C(-R 5)(-R 6)-(CH 2) n -COOR 7] z; and a C 1 -C 10 saturated or unsaturated, straight or branched, cyclic or acyclic, chiral or achiral hydrocarbyl group, wherein optionally at least one carbon atom of the hydrocarbyl group is replaced by -N(-R 1)-, -O- or -S-; wherein at least the 4-position of both Q 1 and Q 2 is substituted, and one of Q 1 and Q 2 is substituted with a substituent other than unsubstituted phenyl; X is -CH 2 -; Y is -S(=O) 2 -; R 1 is selected from the group consisting of H and a C 1 -C 10 saturated or unsaturated, straight or branched, cyclic or acyclic, chiral or achiral hydrocarbyl group, wherein optionally at least one carbon atom of the hydrocarbyl group is replaced by -N(-R 1)-, -O- or -S-; R 3 and R 4 are each H; R 5 and R 6 are each independently selected from the group consisting of H; halo; and C 1 -C 10 saturated or unsaturated, straight or branched, cyclic or acyclic, chiral or achiral hydrocarbyl group, optionally substituted with one or more of halogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, hydroxy, carboxy, carboxamido, amino, (C 1 -C 6) alkyl, (C 1 -C 6) dialkyl amino, or acylamino; or R 5 and R 6 may combine to form a saturated or unsaturated carbocyclic ring with from 3 to 6 carbon atoms, wherein one or more carbon atoms is optionally replaced with -N(-R 1)-, -O-, or -S-; R 7 is selected from the group consisting of H; and a C 1 -C 10 saturated or unsaturated, straight or branched, cyclic or acyclic, chiral or achiral hydrocarbyl group; and an inorganic cation or an organic cation to form a salt; R 8 is selected from the group consisting of H and (C 1 -C 7) hydrocarbyl; R 9 is selected from the group consisting of H and -(CH 2) m -C(-R 5)(-R 6)-(CH 2) n -COOR 7; R 10 is selected from the group consisting of H, branched or unbranched (C 1 -C 6)alkyl, and (C 2 -C 8)acyl; R 11 is selected from the group consisting of H, branched or unbranched (C 1 -C 6)alkyl, and (C 2 -C 8)acyl; m and n are each independently 0-2; and z is 1-2.