A system (300, 400, 600) for applying a mechanical strain to a portion of skin, said system including an appliance (302, 402, 500) and an end effector (304, 404, 606), said appliance (302, 402, 500) including: a drive motor assembly, a drive motor, a drive shaft or mounting arm, a drive control, a power storage source, wherein said drive control is configured and arranged to selectively deliver power from the power storage source to the drive motor assembly, wherein said drive control includes a power adjust or mode control button coupled to control circuitry, such as a programmed microcontroller or processor, which is configured to control the delivery of power to the drive motor assembly, wherein the drive motor is configured to drive the end effector (304, 404, 606), and thus to impart oscillatory motion at an oscillation frequency to the end effector (304, 404, 606) in a first rotational direction and a second rotational direction, wherein the end effector includes a plurality of contact points being the first portions to contact the portion of skin as the end effector is lowered to a portion of skin to be treated with the end effector, characterized in that the contact points on the end effector are equidistantly positioned at a target distance, where the target distance is calculated based on the equation target distance 106 = n × propagation speed target frequency where the propagation speed equals 2 meters per second and the target frequency is a desired oscillation frequency of the end effector at which the oscillatory motion is imparted to the end effector and a cyclical response within a portion of the skin is to be induced, and n is an integer, and where the target frequency is in particular in a range from about 30 Hz to about 140 Hz, the appliance further includes a user-activated input configured to activate the end effector to act as cyclical mechanical strain component for a predetermined treatment time period at the oscillation frequency. a drive motor assembly, a drive motor, a drive shaft or mounting arm, a drive control, a power storage source, wherein said drive control is configured and arranged to selectively deliver power from the power storage source to the drive motor assembly, wherein said drive control includes a power adjust or mode control button coupled to control circuitry, such as a programmed microcontroller or processor, which is configured to control the delivery of power to the drive motor assembly, wherein the drive motor is configured to drive the end effector (304, 404, 606), and thus to impart oscillatory motion at an oscillation frequency to the end effector (304, 404, 606) in a first rotational direction and a second rotational direction, wherein the end effector includes a plurality of contact points being the first portions to contact the portion of skin as the end effector is lowered to a portion of skin to be treated with the end effector, characterized in that the contact points on the end effector are equidistantly positioned at a target distance, where the target distance is calculated based on the equation target distance 106 = n × propagation speed target frequency where the propagation speed equals 2 meters per second and the target frequency is a desired oscillation frequency of the end effector at which the oscillatory motion is imparted to the end effector and a cyclical response within a portion of the skin is to be induced, and n is an integer, and where the target frequency is in particular in a range from about 30 Hz to about 140 Hz, the appliance further includes a user-activated input configured to activate the end effector to act as cyclical mechanical strain component for a predetermined treatment time period at the oscillation frequency.