A compound of Formula I or a salt thereof: R 1 is a 6-membered aryl or heteroaryl ring optionally substituted with one or more substituent groups independently selected from the group consisting of halogen, hydroxyl, linear C1-C4 alkyl, branched C1-C4 alkyl, linear C1-C4 alkoxy, and branched C 1-C4 alkoxy; R 2 is selected from the group consisting of hydrogen, linear C1-C4 alkyl and branched C1-C4 alkyl; X is selected from the group consisting of -CH 2 -, -CH 2 CH 2 -, -CH 2 O- and - CH -, wherein Z is halogen; and Q is selected from the group consisting of -CH=CR 3 C NR 4 R 5, -C≡CC NR 4 R 5, and wherein R 3 is hydrogen or halogen, wherein -NR 4 R 5 either forms a 4-7 membered heterocyclic ring or does not form a ring structure, the heterocylic ring being either heteroaryl or heterocycloalkyl ring, wherein when -NR 4 R 5 forms a 4-7 membered heterocyclic ring, the 4-7 membered heterocyclic ring includes an optional second heteroatom in addition to the nitrogen of -NR 4 R 5 and is optionally substituted with one or more substituent groups independently selected from the group consisting of linear C1-C6 alkyl, branched C1-C6 alkyl, hydroxyl, carboxylic acid, linear C1-C4 alkyl carboxylic acid, and branched C1-C4 alkyl carboxylic acid, wherein when -NR 4 R 5 does not form a ring structure, R 4 is selected from the group consisting of hydrogen, linear C1-C6 alkyl and branched C1-C6 alkyl, and R 5 is selected from the group consisting of hydrogen, linear C1-C6 alkyl optionally substituted with at least one fluorine or at least one hydroxyl, branched C1-C6 alkyl optionally substituted with at least one fluorine or at least one hydroxyl, and C1-C6 cycloalkyl optionally substituted with at least one fluorine or at least one hydroxyl, wherein Y 1, Y 2, Y 3, and Y 4 are each independently selected from the group consisting of -CH, N, O, S, -CR 6, and -NR 6, wherein R 6 is selected from the group consisting of hydrogen, linear C1-C4 alkyl, branched C1-C4 alkyl, 5-6 membered aryl ring, 5-6 membered heteroaryl ring, 3-7 membered heterocycloalkyl ring, 3-7 membered cycloalkyl ring, -NHCO-(aryl ring), and -CH 2 CO-(C3-C6 membered heterocylic ring). R 1 is a 6-membered aryl or heteroaryl ring optionally substituted with one or more substituent groups independently selected from the group consisting of halogen, hydroxyl, linear C1-C4 alkyl, branched C1-C4 alkyl, linear C1-C4 alkoxy, and branched C 1-C4 alkoxy; R 2 is selected from the group consisting of hydrogen, linear C1-C4 alkyl and branched C1-C4 alkyl; X is selected from the group consisting of -CH 2 -, -CH 2 CH 2 -, -CH 2 O- and - CH -, wherein Z is halogen; and Q is selected from the group consisting of -CH=CR 3 C NR 4 R 5, -C≡CC NR 4 R 5, and wherein R 3 is hydrogen or halogen, wherein -NR 4 R 5 either forms a 4-7 membered heterocyclic ring or does not form a ring structure, the heterocylic ring being either heteroaryl or heterocycloalkyl ring, wherein when -NR 4 R 5 forms a 4-7 membered heterocyclic ring, the 4-7 membered heterocyclic ring includes an optional second heteroatom in addition to the nitrogen of -NR 4 R 5 and is optionally substituted with one or more substituent groups independently selected from the group consisting of linear C1-C6 alkyl, branched C1-C6 alkyl, hydroxyl, carboxylic acid, linear C1-C4 alkyl carboxylic acid, and branched C1-C4 alkyl carboxylic acid, wherein when -NR 4 R 5 does not form a ring structure, R 4 is selected from the group consisting of hydrogen, linear C1-C6 alkyl and branched C1-C6 alkyl, and R 5 is selected from the group consisting of hydrogen, linear C1-C6 alkyl optionally substituted with at least one fluorine or at least one hydroxyl, branched C1-C6 alkyl optionally substituted with at least one fluorine or at least one hydroxyl, and C1-C6 cycloalkyl optionally substituted with at least one fluorine or at least one hydroxyl, wherein Y 1, Y 2, Y 3, and Y 4 are each independently selected from the group consisting of -CH, N, O, S, -CR 6, and -NR 6, wherein R 6 is selected from the group consisting of hydrogen, linear C1-C4 alkyl, branched C1-C4 alkyl, 5-6 membered aryl ring, 5-6 membered heteroaryl ring, 3-7 membered heterocycloalkyl ring, 3-7 membered cycloalkyl ring, -NHCO-(aryl ring), and -CH 2 CO-(C3-C6 membered heterocylic ring).