A railway train safety monitoring and processing method based on radio block center, comprising: detecting, by the radio block center, whether communication between the radio block center and an Interlocking fails or not; when a communication failure between the radio block center and the Interlocking occurs, stopping sending, by the radio block center, messages to all railway trains in a control range of the Interlocking or to all railway trains whose movement authority extend in the control range of the Interlocking; if a communication failure between the radio block center and a railway train is detected by the radio block center, reserving, by the radio block center, the movement authority of a railway train for a predetermined time, and not allocating routes contained in the movement authority to other railway trains; if a handing over radio block center detects a handover process between the handing over radio block center and a accepting radio block center has not been started, and communication connection between the handing over radio block center and the accepting radio block center is disconnected, monitoring, by the handing over radio block center, operation of the railway train till the border between the handing over radio block center and the accepting radio block center, but not extending movement authority to control range of the accepting radio block center; if a handing over radio block center detects a handover process between the handing over radio block center and a accepting radio block center has already been started, and communication connection between the handing over radio block center and the accepting radio block center is disconnected, stopping sending, by the handing over radio block center, any message to the railway train on which the handover process takes place; if the accepting radio block center detects a handover process between the accepting radio block center and the handing over radio block center has already been started, and its connection with the railway train is not yet established, and then communication connection between the accepting radio block center and the handing over radio block center is disconnected, deleting, by the accepting radio block center, information related to the railway train on which the handover process takes place; if the accepting radio block center detects a handover process between the accepting radio block center and the handing over radio block center has already been started, and the connection with the railway train is established, and then communication connection between the accepting radio block center and the handing over radio block center is disconnected, reserving, by the accepting radio block center, information related to the railway train on which the handover process takes place. detecting, by the radio block center, whether communication between the radio block center and an Interlocking fails or not; when a communication failure between the radio block center and the Interlocking occurs, stopping sending, by the radio block center, messages to all railway trains in a control range of the Interlocking or to all railway trains whose movement authority extend in the control range of the Interlocking; if a communication failure between the radio block center and a railway train is detected by the radio block center, reserving, by the radio block center, the movement authority of a railway train for a predetermined time, and not allocating routes contained in the movement authority to other railway trains; if a handing over radio block center detects a handover process between the handing over radio block center and a accepting radio block center has not been started, and communication connection between the handing over radio block center and the accepting radio block center is disconnected, monitoring, by the handing over radio block center, operation of the railway train till the border between the handing over radio block center and the accepting radio block center, but not extending movement authority to control range of the accepting radio block center; if a handing over radio block center detects a handover process between the handing over radio block center and a accepting radio block center has already been started, and communication connection between the handing over radio block center and the accepting radio block center is disconnected, stopping sending, by the handing over radio block center, any message to the railway train on which the handover process takes place; if the accepting radio block center detects a handover process between the accepting radio block center and the handing over radio block center has already been started, and its connection with the railway train is not yet established, and then communication connection between the accepting radio block center and the handing over radio block center is disconnected, deleting, by the accepting radio block center, information related to the railway train on which the handover process takes place; if the accepting radio block center detects a handover process between the accepting radio block center and the handing over radio block center has already been started, and the connection with the railway train is established, and then communication connection between the accepting radio block center and the handing over radio block center is disconnected, reserving, by the accepting radio block center, information related to the railway train on which the handover process takes place.