An intracorporeal fluid delivery device for heating a fluid to be administered to a patient, the device characterized by: an outer shell including an activation aperture, wherein the outer shell comprises an inner impermeable layer with the activation aperture, and an outer layer with the activation aperture, wherein the inner layer and the outer layer surround an internal enclosure, a heat generation layer, and a heater activation system within the outer shell; wherein the heat generation layer comprises at least one first liquid permeable heater comprising a first exothermic reactant; an intracorporeal fluid conduit attached to the outside of outer shell with a fastener, adhesive or other suitable mounting mechanism or holder or disposed between outer layer and inner impermeable layer or disposed internal to impermeable layer that is inside internal enclosure and contacting heat generation layer and/or heater activation system; wherein the intracorporeal fluid conduit has a path through the device, and wherein the intracorporeal conduit further comprises an inlet port adjacent to a proximal end of the device and an outlet port adjacent to a distal end of the device; whereby the heater activation system comprises at least one sealed bladder disposed inside the internal enclosure adjacent to the heat generation layer; and an activator liquid disposed in the at least one sealed bladder; wherein the activator liquid when released from the at least one sealed bladder contacts the heat generation layer and permeates the at least one first liquid permeable heater to combine with the first exothermic reactant causing a first exothermic reaction that heats fluids in the intracorporeal fluid conduit. an outer shell including an activation aperture, wherein the outer shell comprises an inner impermeable layer with the activation aperture, and an outer layer with the activation aperture, wherein the inner layer and the outer layer surround an internal enclosure, a heat generation layer, and a heater activation system within the outer shell; wherein the heat generation layer comprises at least one first liquid permeable heater comprising a first exothermic reactant; an intracorporeal fluid conduit attached to the outside of outer shell with a fastener, adhesive or other suitable mounting mechanism or holder or disposed between outer layer and inner impermeable layer or disposed internal to impermeable layer that is inside internal enclosure and contacting heat generation layer and/or heater activation system; wherein the intracorporeal fluid conduit has a path through the device, and wherein the intracorporeal conduit further comprises an inlet port adjacent to a proximal end of the device and an outlet port adjacent to a distal end of the device; whereby the heater activation system comprises at least one sealed bladder disposed inside the internal enclosure adjacent to the heat generation layer; and an activator liquid disposed in the at least one sealed bladder; at least one sealed bladder disposed inside the internal enclosure adjacent to the heat generation layer; and an activator liquid disposed in the at least one sealed bladder; wherein the activator liquid when released from the at least one sealed bladder contacts the heat generation layer and permeates the at least one first liquid permeable heater to combine with the first exothermic reactant causing a first exothermic reaction that heats fluids in the intracorporeal fluid conduit.