Method for producing a printed matter, in particular a multi-part patient information leaflet for a pharmaceutical product, from a single print sheet, comprising a long side and a transverse side, characterised by at least the following steps, which are carried out in the following or, where technically possible, in a deviating sequence: i) application of at least four adhesive strips (44a-d) extending in a longitudinal direction and offset from each other in a transverse direction or at least two adhesive areas extending in a longitudinal direction and offset from each other in a transverse direction, on one or both sides of the print sheet, ii) implementation of one or more longitudinal folds with fold lines extending transverse to the longitudinal direction in such a way that adhesions (44a,b and 44c,d) are formed through cooperation of the adhesive strips (44a-d) or the adhesive areas, which connect overlaying print sheet areas, iii) insertion of at least two perforations (42a, 42c) into the print sheet in a longitudinal direction and offset from each other in transverse direction in such a way that each perforation lies between two adjacent adhesive strips (44a,b or 44c,d) or within one adhesive area, iv) application of a further adhesive (48a, 48b) onto at least one outside area of the longitudinally folded print sheet directed towards at least one of the adhesions (44a,b or 44c,d), v) realisation of a transverse fold with a fold line extending transverse to the transverse direction, and thus adhesion of the two transversely folded parts by means of the previously applied further adhesive in such a way that adhesions (44a,b and 44c,d) are adhered to each other by the further adhesive (48a, 48b) in an overlaying way, so that the page number resulting for the final product of the printed matter is doubled and a consistently adhesion-bound printed matter is created, vi) realisation of a bleed of the print sheet processed in this way on at least one side transverse to the adhesions and in the area of the transverse fold, wherein the correspondingly processed product comprises at least two parts (46a, 46b), each following the other, in a longitudinal condition, which are separately connected with each other on at least one perforation, wherein each part (46a, 46b) is bound in a book-like fashion in the separated condition. i) application of at least four adhesive strips (44a-d) extending in a longitudinal direction and offset from each other in a transverse direction or at least two adhesive areas extending in a longitudinal direction and offset from each other in a transverse direction, on one or both sides of the print sheet, ii) implementation of one or more longitudinal folds with fold lines extending transverse to the longitudinal direction in such a way that adhesions (44a,b and 44c,d) are formed through cooperation of the adhesive strips (44a-d) or the adhesive areas, which connect overlaying print sheet areas, iii) insertion of at least two perforations (42a, 42c) into the print sheet in a longitudinal direction and offset from each other in transverse direction in such a way that each perforation lies between two adjacent adhesive strips (44a,b or 44c,d) or within one adhesive area, iv) application of a further adhesive (48a, 48b) onto at least one outside area of the longitudinally folded print sheet directed towards at least one of the adhesions (44a,b or 44c,d), v) realisation of a transverse fold with a fold line extending transverse to the transverse direction, and thus adhesion of the two transversely folded parts by means of the previously applied further adhesive in such a way that adhesions (44a,b and 44c,d) are adhered to each other by the further adhesive (48a, 48b) in an overlaying way, so that the page number resulting for the final product of the printed matter is doubled and a consistently adhesion-bound printed matter is created, vi) realisation of a bleed of the print sheet processed in this way on at least one side transverse to the adhesions and in the area of the transverse fold,