A wheelchair comprising a frame and two main drive wheels (10,20) each coupled to a hand-rim (11,21) for actuating the wheels in both directions of rotation and for braking, characterized in that said frame is equipped: • on the right-hand side in relation to the normal direction of movement ∘ by a connecting means with a side shaft locking in a clockwise direction and freely rotating in a counterclockwise direction ∘ the right hand-rim being mounted freely rotating in relation to said side shaft, without freedom of axial translation ∘ the right wheel being provided with a hub connected to the hand-rim by a connecting means locking in the clockwise direction ∘ said hub comprising a means of braking the rotation of the hub in relation to the side shaft, actuated by a counterclockwise movement of said hand-rim in relation to the side shaft • on the left-hand side in relation to the normal direction of movement ∘ by a left connecting means with a side shaft locking in the counterclockwise direction and freely rotating in the clockwise direction ∘ the left hand-rim being mounted freely rotating in relation to the side shaft, without freedom of axial translation ∘ the left wheel being provided with a hub connected to the hand-rim by a connecting hub locking in the counterclockwise direction ∘ said hub comprising a means of braking the rotation of the hub in relation to the side shaft, actuated by the clockwise movement of the hand-rim in relation to the side shaft. • on the right-hand side in relation to the normal direction of movement ∘ by a connecting means with a side shaft locking in a clockwise direction and freely rotating in a counterclockwise direction ∘ the right hand-rim being mounted freely rotating in relation to said side shaft, without freedom of axial translation ∘ the right wheel being provided with a hub connected to the hand-rim by a connecting means locking in the clockwise direction ∘ said hub comprising a means of braking the rotation of the hub in relation to the side shaft, actuated by a counterclockwise movement of said hand-rim in relation to the side shaft ∘ by a connecting means with a side shaft locking in a clockwise direction and freely rotating in a counterclockwise direction ∘ the right hand-rim being mounted freely rotating in relation to said side shaft, without freedom of axial translation ∘ the right wheel being provided with a hub connected to the hand-rim by a connecting means locking in the clockwise direction ∘ said hub comprising a means of braking the rotation of the hub in relation to the side shaft, actuated by a counterclockwise movement of said hand-rim in relation to the side shaft • on the left-hand side in relation to the normal direction of movement ∘ by a left connecting means with a side shaft locking in the counterclockwise direction and freely rotating in the clockwise direction ∘ the left hand-rim being mounted freely rotating in relation to the side shaft, without freedom of axial translation ∘ the left wheel being provided with a hub connected to the hand-rim by a connecting hub locking in the counterclockwise direction ∘ said hub comprising a means of braking the rotation of the hub in relation to the side shaft, actuated by the clockwise movement of the hand-rim in relation to the side shaft. ∘ by a left connecting means with a side shaft locking in the counterclockwise direction and freely rotating in the clockwise direction ∘ the left hand-rim being mounted freely rotating in relation to the side shaft, without freedom of axial translation ∘ the left wheel being provided with a hub connected to the hand-rim by a connecting hub locking in the counterclockwise direction ∘ said hub comprising a means of braking the rotation of the hub in relation to the side shaft, actuated by the clockwise movement of the hand-rim in relation to the side shaft.