mhurhangee/ep-ind-claims huggingface dataset:
An insertion device (100; 200), comprising: an elongate member (110; 210) having a proximal end portion (112; 212), a distal end portion (113; 213), and defining a lumen therethrough, the elongate member (110; 210) including a curved portion (111; 211) between the proximal end portion (112; 212) and the distal end portion (113; 213), the lumen being configured to receive a portion of a tissue anchor (190; 290) to removably couple the tissue anchor (190; 290) to the distal end portion (113; 213), the proximal end portion (112; 212) including a handle (170; 270) defining a longitudinal axis (B1-B1); and a stylet having a proximal end portion, a distal end portion and being configured to move proximally from a first position to a second position with respect to the elongate member (110; 210), the stylet configured to engage the tissue anchor (190; 290) to remove the tissue anchor (190; 290) from the elongate member (110; 210) when the stylet is moved distally from its second position to its first position, wherein a longitudinal axis (YY-YY, B-B) defined by the distal end portion (113; 213) of the elongate member (110; 210) is angled with respect to a longitudinal axis (XX-XX, A-A) defined by the proximal end portion (112; 212) of the elongate member (110; 210), wherein the stylet is disposed against an inner surface of the elongate member (110; 210) when the stylet is in the second position. an elongate member (110; 210) having a proximal end portion (112; 212), a distal end portion (113; 213), and defining a lumen therethrough, the elongate member (110; 210) including a curved portion (111; 211) between the proximal end portion (112; 212) and the distal end portion (113; 213), the lumen being configured to receive a portion of a tissue anchor (190; 290) to removably couple the tissue anchor (190; 290) to the distal end portion (113; 213), the proximal end portion (112; 212) including a handle (170; 270) defining a longitudinal axis (B1-B1); and a stylet having a proximal end portion, a distal end portion and being configured to move proximally from a first position to a second position with respect to the elongate member (110; 210), the stylet configured to engage the tissue anchor (190; 290) to remove the tissue anchor (190; 290) from the elongate member (110; 210) when the stylet is moved distally from its second position to its first position, wherein a longitudinal axis (YY-YY, B-B) defined by the distal end portion (113; 213) of the elongate member (110; 210) is angled with respect to a longitudinal axis (XX-XX, A-A) defined by the proximal end portion (112; 212) of the elongate member (110; 210), wherein the stylet is disposed against an inner surface of the elongate member (110; 210) when the stylet is in the second position.
An isolated antibody that is internalized into a cell via a macropinocytosis pathway, wherein said antibody is an antibody that binds to ephrin type A receptor 2 (EphA2), and wherein: said antibody comprises the amino acid sequence SYSMN for VH CDR1, the amino acid sequence YISSSSSTIYYADSVKG for VH CDR2, the amino acid sequence YRLPDFWSGYPNYGMDV for VH CDR3, the amino acid sequence TGSSSNIGAGYDVH for VL CDR1, the amino acid sequence YGNSNRPS for VL CDR2, and the amino acid sequence QSYDSSLSGHVV for VL CDR3; or said antibody comprises the amino acid sequence SYAMS for VH CDR1, the amino acid sequence AISGSGGSTYYADSVKG for VH CDR2, the amino acid sequence LSVEWYGSGSYLGY for VH CDR3, the amino acid sequence QGDSLRSYYAS for VL CDR1, the amino acid sequence YGKNNRPS for VL CDR2, and the amino acid sequence NSRDSSANHVV for VL CDR3. said antibody comprises the amino acid sequence SYSMN for VH CDR1, the amino acid sequence YISSSSSTIYYADSVKG for VH CDR2, the amino acid sequence YRLPDFWSGYPNYGMDV for VH CDR3, the amino acid sequence TGSSSNIGAGYDVH for VL CDR1, the amino acid sequence YGNSNRPS for VL CDR2, and the amino acid sequence QSYDSSLSGHVV for VL CDR3; or said antibody comprises the amino acid sequence SYAMS for VH CDR1, the amino acid sequence AISGSGGSTYYADSVKG for VH CDR2, the amino acid sequence LSVEWYGSGSYLGY for VH CDR3, the amino acid sequence QGDSLRSYYAS for VL CDR1, the amino acid sequence YGKNNRPS for VL CDR2, and the amino acid sequence NSRDSSANHVV for VL CDR3.
Injector having an injector body and a nozzle body with a borehole (4, 4a) which accommodates a nozzle needle, wherein the nozzle needle can be moved in a translatory fashion in the borehole (4, 4a) and has a nozzle needle tip which interacts with a nozzle needle seat, wherein at least one nozzle opening is assigned to the nozzle needle seat and is connected, under control by the nozzle needle, to a high-pressure line (10, 10a) for a medium in the injector body and the nozzle body, and wherein a sensor is provided for recording a pressure profile of the medium, characterized in that the sensor is inserted into a pocket-shaped groove, embodied as a slot, of the injector, wherein one of the longitudinal sides of the groove which lie opposite one another is oriented laterally and in parallel with the high-pressure line (10, 10a), and the sensor is arranged with its sensor longitudinal sides which experience deformation and convert it into a signal, between the two opposite longitudinal sides of the groove.
A lithium sulfur battery comprising: a positive electrode and a negative electrode disposed opposite to each other; a separator positioned between the positive electrode and the negative electrode; and a gel polymer electrolyte positioned between the separator and the positive electrode, wherein the gel polymer electrolyte comprises LiNO 3, wherein the gel polymer electrolyte comprises a polymer matrix, and an organic solvent and a lithium salt supported on the polymer matrix, and wherein the polymer matrix is prepared by polymerizing a trimethylolpropane ethoxylate triacrylate monomer, the trimethylolpropane ethoxylate triacrylate having a weight average molecular weight of from 200 g/mol to 1000 g/mol. a positive electrode and a negative electrode disposed opposite to each other; a separator positioned between the positive electrode and the negative electrode; and a gel polymer electrolyte positioned between the separator and the positive electrode, wherein the gel polymer electrolyte comprises LiNO 3, wherein the gel polymer electrolyte comprises a polymer matrix, and an organic solvent and a lithium salt supported on the polymer matrix, and wherein the polymer matrix is prepared by polymerizing a trimethylolpropane ethoxylate triacrylate monomer, the trimethylolpropane ethoxylate triacrylate having a weight average molecular weight of from 200 g/mol to 1000 g/mol.
A semiconductor package (1, 1', 1"), the package (1, 1', 1") comprising: - a first substrate comprising at a front cavity side a plurality of cavities (6, 6'), each of the cavities (6, 6') having a bottom wall and side walls, and having a conductive path forming an electric contact surface located at the inner side of the bottom wall of the cavity (6, 6'), - a plurality of semiconductor elements (16, 17), each of the semiconductor elements (16, 17) comprising a first electric contact surface on a first side and a second electric contact surface on a second side opposite to the first side, wherein at least one of the semiconductor elements (16, 17) is placed within a corresponding cavity (6, 6') at the front cavity side of the first substrate, wherein the first electric contact of the semiconductor element (16, 17) and the electric contact surface at the inner side of the bottom wall of the corresponding cavity (6, 6') are electrically conductive bonded in a material-locking manner, and - a second substrate, the second substrate being attached with a connection side (12, 13) to the front cavity side of the first substrate thereby encapsulating the semiconductor elements (16, 17) located within the corresponding cavities (6, 6') at the front cavity side of the first substrate, characterized in that a third substrate is further comprised, the third substrate being attached with a connection side (12, 13) to the first substrate or to the second substrate, respectively. - a first substrate comprising at a front cavity side a plurality of cavities (6, 6'), each of the cavities (6, 6') having a bottom wall and side walls, and having a conductive path forming an electric contact surface located at the inner side of the bottom wall of the cavity (6, 6'), - a plurality of semiconductor elements (16, 17), each of the semiconductor elements (16, 17) comprising a first electric contact surface on a first side and a second electric contact surface on a second side opposite to the first side, wherein at least one of the semiconductor elements (16, 17) is placed within a corresponding cavity (6, 6') at the front cavity side of the first substrate, wherein the first electric contact of the semiconductor element (16, 17) and the electric contact surface at the inner side of the bottom wall of the corresponding cavity (6, 6') are electrically conductive bonded in a material-locking manner, and - a second substrate, the second substrate being attached with a connection side (12, 13) to the front cavity side of the first substrate thereby encapsulating the semiconductor elements (16, 17) located within the corresponding cavities (6, 6') at the front cavity side of the first substrate, characterized in that a third substrate is further comprised, the third substrate being attached with a connection side (12, 13) to the first substrate or to the second substrate, respectively.
A method for determining whether an input image is sufficiently sharp, comprising the steps of - providing a blur score threshold value, - inputting the input image to an image processing system, - generating, by the image processing system, a two-dimensional frequency spectrum of the input image, - generating a one-dimensional frequency spectrum from the two-dimensional frequency spectrum, - fitting a straight line on the one-dimensional frequency spectrum, and - determining a blur score value based on a residual of the fitting, and considering the input image as sufficiently sharp based on a comparison of the blur score value with the blur score threshold value. - providing a blur score threshold value, - inputting the input image to an image processing system, - generating, by the image processing system, a two-dimensional frequency spectrum of the input image, - generating a one-dimensional frequency spectrum from the two-dimensional frequency spectrum, - fitting a straight line on the one-dimensional frequency spectrum, and - determining a blur score value based on a residual of the fitting, and considering the input image as sufficiently sharp based on a comparison of the blur score value with the blur score threshold value.
A multiple-cell tank for use in winemaking, which comprises a supporting frame for a tank body which comprises a bottom wall, a top wall and a lateral shell, at least two containment cells (11, 12) being defined inside said tank body and being mutually hermetically separated by at least one separation partition, characterized in that said at least one separation partition extends between said bottom wall and said top wall, at said lateral shell there being at least one first and at least one second access hatch (11a, 11b), which lead into a respective containment cell (11, 12), and are arranged substantially at the same height with respect to said bottom wall, at said top wall there being at least one first and at least one second evacuation stack (12a, 12b) in communication with a respective containment cell (11, 12).
A method of unmasking an endotoxin in a composition, preferably a pharmaceutical composition, comprising an endotoxin masker and suspected of comprising said endotoxin, said method comprising the step of adding to said composition a modulator capable of unmasking said endotoxin, wherein said endotoxin masker is a substance which, in solution with endotoxin, renders the endotoxin undetectable by available detection methods, and wherein said modulator comprises a first heteroatom-substituted aliphatic, wherein said first heteroatom-substituted aliphatic is an aliphatic alcohol comprising 8 to 16 carbon atoms.
A system configured to record a position and orientation of a dental component, the system comprising: a coping comprising: an anti-rotational feature that is configured to mate with an anti-rotational feature of the dental component, and an orientation feature that is configured to convey the orientation of the dental component; and a replica of the dental component comprising: a first anti-rotational feature that corresponds to the anti-rotational feature of the dental component, and a second anti-rotational feature that does not correspond to the anti-rotational feature of the dental component, wherein the second anti-rotational feature of the replica is positioned on a surface configured to mate with an adjacent component, wherein the adjacent component comprises the coping, an abutment, and/or a prosthesis. a coping comprising: an anti-rotational feature that is configured to mate with an anti-rotational feature of the dental component, and an orientation feature that is configured to convey the orientation of the dental component; and an anti-rotational feature that is configured to mate with an anti-rotational feature of the dental component, and an orientation feature that is configured to convey the orientation of the dental component; and a replica of the dental component comprising: a first anti-rotational feature that corresponds to the anti-rotational feature of the dental component, and a second anti-rotational feature that does not correspond to the anti-rotational feature of the dental component, wherein the second anti-rotational feature of the replica is positioned on a surface configured to mate with an adjacent component, wherein the adjacent component comprises the coping, an abutment, and/or a prosthesis. a first anti-rotational feature that corresponds to the anti-rotational feature of the dental component, and a second anti-rotational feature that does not correspond to the anti-rotational feature of the dental component, wherein the second anti-rotational feature of the replica is positioned on a surface configured to mate with an adjacent component, wherein the adjacent component comprises the coping, an abutment, and/or a prosthesis.
A syringe device comprising: a syringe barrel; a piston having a first end insertable within the syringe barrel, a second end opposing the first end, and an overall length defined between the first and second ends; a piston seal disposed at the first end of the piston, the piston seal being over-molded onto a stem portion of the piston; a vial port disposed within the piston configured to receive a vial in lengthwise orientation along a portion of the overall length of the piston; and a fluid passageway extending through the piston from the vial port through the first end and through the piston seal; characterized by: a valve having a valve axis and configured to fit into an opening in a side of the piston, the valve axis orthogonally traversing the fluid passageway. a syringe barrel; a piston having a first end insertable within the syringe barrel, a second end opposing the first end, and an overall length defined between the first and second ends; a piston seal disposed at the first end of the piston, the piston seal being over-molded onto a stem portion of the piston; a vial port disposed within the piston configured to receive a vial in lengthwise orientation along a portion of the overall length of the piston; and a fluid passageway extending through the piston from the vial port through the first end and through the piston seal; characterized by: a valve having a valve axis and configured to fit into an opening in a side of the piston, the valve axis orthogonally traversing the fluid passageway.
A compound selected from the group consisting of the pantothenamide analogues represented by formula: wherein ring E represents an unsubstituted phenyl ring or a phenyl substituted with 1-3 substituents independently selected from nitril and halo or a pharmaceutically acceptable salt thereof.
An apparatus for mechanically loading a biological sample, comprising: a hermetically sealable container, for housing the biological sample; a ferromagnetic element, for attachment to the biological sample within the container; and a solenoid for generating a magnetic field within the container, so as to apply a force to the ferromagnetic element, the solenoid having a solenoid axis; wherein: the solenoid is configured, when energised by a constant current, to produce a force on the ferromagnetic element that varies by less than a predetermined amount over a predetermined range of movement of the ferromagnetic element within the container; characterized in that the solenoid has a hole or recess along the axis for at least partially receiving the container and in that the container is positioned at least partly within the solenoid so that the ferromagnetic element within the container is within the solenoid. a hermetically sealable container, for housing the biological sample; a ferromagnetic element, for attachment to the biological sample within the container; and a solenoid for generating a magnetic field within the container, so as to apply a force to the ferromagnetic element, the solenoid having a solenoid axis; wherein: the solenoid is configured, when energised by a constant current, to produce a force on the ferromagnetic element that varies by less than a predetermined amount over a predetermined range of movement of the ferromagnetic element within the container;
A method for prioritizing one of a device-to-device, D2D, transmission and a D2D reception in a wireless communication system, the method performed by a user equipment, UE, (10, 900) and comprising: prioritizing one of the D2D transmission and the D2D reception over another based on whether priority information is present or not, when both the D2D transmission and the D2D reception are scheduled at a same subframe and both the D2D transmission and the D2D reception are not possible at the same subframe simultaneously, and performing the D2D transmission or the D2D reception at the same subframe based on the prioritization, wherein if the priority information is present, the UE performs the D2D transmission or the D2D reception according to the priority information, and wherein if the priority information is not present and the D2D transmission is a vehicle to everything, V2X, transmission, the V2X transmission is prioritized over the D2D reception and the UE performs V2X transmission. prioritizing one of the D2D transmission and the D2D reception over another based on whether priority information is present or not, when both the D2D transmission and the D2D reception are scheduled at a same subframe and both the D2D transmission and the D2D reception are not possible at the same subframe simultaneously, and performing the D2D transmission or the D2D reception at the same subframe based on the prioritization, wherein if the priority information is present, the UE performs the D2D transmission or the D2D reception according to the priority information, and wherein if the priority information is not present and the D2D transmission is a vehicle to everything, V2X, transmission, the V2X transmission is prioritized over the D2D reception and the UE performs V2X transmission.
A continuous process for the simultaneous hydration of an olefin feedstream which contains principally mixed butenes, and includes at least two butene isomers to produce mixed butanols, the process comprising: a. providing a reaction vessel containing water, an acid hydration catalyst and liquefied olefins containing butene isomers; b. promoting the hydration of the butene isomers to form mixed butanols and the extraction of the butanols from the aqueous phase by the butene isomers in the liquid olefin phase; c. removing the olefins containing butene isomers enriched with mixed butanol reaction products extracted from the first aqueous phase; d. separating the mixed butanols from the olefins containing butene isomers to form a mixed butanol product stream and a lean olefin stream; e. recovering the mixed butanol product stream; and f. returning the lean olefin containing butene isomer stream to the reaction vessel. a. providing a reaction vessel containing water, an acid hydration catalyst and liquefied olefins containing butene isomers; b. promoting the hydration of the butene isomers to form mixed butanols and the extraction of the butanols from the aqueous phase by the butene isomers in the liquid olefin phase; c. removing the olefins containing butene isomers enriched with mixed butanol reaction products extracted from the first aqueous phase; d. separating the mixed butanols from the olefins containing butene isomers to form a mixed butanol product stream and a lean olefin stream; e. recovering the mixed butanol product stream; and f. returning the lean olefin containing butene isomer stream to the reaction vessel.
Electronic circuit arrangement with (a) a carrier circuit board, (b) a multi-layer substrate (47, 65) which is arranged with its underside on the carrier circuit board, (c) at least one opening in at least one layer of the substrate (47, 65) on its underside, (d) at least one heat-radiating component which is arranged on the underside of the substrate (47, 65) in the opening, (e) at least one cooling element arranged on the upper side of the substrate (47, 65), (f) a spacer between the cooling element and the upper side of the substrate (47, 65), wherein the cross-sectional area of the spacer is less than that of the cooling element, (g) at least one feed through (44, 60) which passes completely through the substrate (47, 65) and connects the heat-radiating component with the cooling element, and (h) an electrical connection of the multi-layer substrate (47, 65) with the carrier circuit board. (a) a carrier circuit board, (b) a multi-layer substrate (47, 65) which is arranged with its underside on the carrier circuit board, (c) at least one opening in at least one layer of the substrate (47, 65) on its underside, (d) at least one heat-radiating component which is arranged on the underside of the substrate (47, 65) in the opening, (e) at least one cooling element arranged on the upper side of the substrate (47, 65), (f) a spacer between the cooling element and the upper side of the substrate (47, 65), wherein the cross-sectional area of the spacer is less than that of the cooling element, (g) at least one feed through (44, 60) which passes completely through the substrate (47, 65) and connects the heat-radiating component with the cooling element, and (h) an electrical connection of the multi-layer substrate (47, 65) with the carrier circuit board.