mhurhangee/ep-ind-claims huggingface dataset:
A phased array transmitter (200, 200') comprising: a splitter (210-A) configured for splitting an IF signal (IF-A) into a plurality of input IF signals (IF-1A, IF-2A, IF-NA); a plurality of transmitting branches each configured for up-converting an input IF signal (IF-1A, IF-2A, IF-NA) to an RF signal (RF-1, RF-2, RF-N) with a desired phase shift φ RF-1A, φ FF-2A, φ RF-NA); and each transmitting branch connected to an antenna element (230-1, 230-2, 230-N) configured for transmitting the RF signal, wherein each transmitting branch of the phased array transmitter (200, 200') is comprising an IF phase shifter (221-1A, 221-2A, 221-NA) configured for phase shifting the input IF signal (IF-1A, IF-2A, IF-NA) with an IF phase shift φ IF-1A, φ IF-2A, φ IF-NA) to obtain a phase shifted IF signal (IF-1', IF-2', IF-N'), an LO phase shifter (222-1, 222-2, 222-N) configured for phase shifting an LO signal with an LO phase shift φ LO-1, φ LO-2, φ LO-N) to obtain a phase shifted LO signal, a mixer (223-1, 223-2, 223-N) configured for mixing the phase shifted IF signal (IF-1', IF-2', IF-N') with the phased shifted LO signal to obtain the RF signal (RF-1, RF-2, RF-N), wherein the combined IF phase shift and LO phase shift is the desired RF phase shift φ RF-1A, φ FF-2A, φ RF-NA) of each transmitting branch; and characterized in that the LO phase shifts φ LO-1, φ LO-2, φ LO-N) are chosen randomly in order to suppress unwanted spurious signals.
A method for the deployment planning and coordination of a vehicle fleet which consists of a plurality of agricultural working vehicles (7, 8), by which different agricultural working procedures are carried out on a field substantially concurrently or at different times, wherein, for carrying out at least one of the agricultural working procedures, the working vehicles (7, 8) have at least one working assembly which is a component of the working vehicle (7, 8) and/or is adapted to the working vehicles (7, 8), wherein at least one working vehicle of the vehicle fleet is operated autonomously, wherein the deployment planning on the field is carried out by means of a database-based management system wherein, when carrying out planning of an agricultural working procedure respectively comprising a sequence of working steps, the autonomous working vehicles which are available to the vehicle fleet to be coordinated are integrated, whereby at least one autonomous working vehicle is associated with each working step of the agricultural working procedure, wherein specific deployment parameters are transmitted by the management system in order to carry out the working step associated with the autonomous working vehicle, through which the at least one autonomous working vehicle is instructed to carry out the associated working step, characterized in that operational parameters for the at least one integrated or adapted working assembly of the autonomous working vehicle are specified and transmitted by the management system as a function of the agricultural working procedure to be carried out by the at least one autonomous working vehicle.
A therapeutically effective amount of atezolizumab for use in a method of treating a patient suffering from a urothelial bladder cancer, the method comprising administering to the patient the therapeutically effective amount of atezolizumab, wherein a tumor sample obtained from the patient has been determined to have an increased level of mutation load relative to a reference level of mutation load, wherein the mutation load of the tumor sample reflects the level of somatic mutations in at least one-third of the genes set forth in Table 1.
Mobile communication antenna for connecting to at least one base station, comprising the following features: - a radome, a reflector arrangement, a plurality of mobile communication radiators and at least one or more electronic modules are provided; - the radome comprises a front wall, a rear wall and side walls; - the reflector arrangement, the plurality of mobile communication radiators and the at least one or more electronic modules are arranged inside the radome; - the plurality of mobile communication radiators are arranged on a front side of the reflector arrangement; - the at least one or the more electronic modules are arranged on a rear side of the reflector arrangement; - at least one electronic module comprises an electronic unit and a module housing, the electronic unit being arranged in the module housing; - the module housing of the at least one electronic module is made of metal or a metal alloy and comprises a front side, a rear side, end faces and side walls, wherein the front side of the module housing of the at least one electronic module points in the direction of the rear wall of the radome and the rear side of the module housing of the at least one electronic module is opposite the front side of the module housing of the at least one electronic module and points towards the front wall of the radome; - at least the surface of the front side and/or the rear side of the module housing of the at least one electronic module is at least predominantly coated with a heat emission layer which has an emissivity ε, with ε ≥ 0.6. - a radome, a reflector arrangement, a plurality of mobile communication radiators and at least one or more electronic modules are provided; - the radome comprises a front wall, a rear wall and side walls; - the reflector arrangement, the plurality of mobile communication radiators and the at least one or more electronic modules are arranged inside the radome; - the plurality of mobile communication radiators are arranged on a front side of the reflector arrangement; - the at least one or the more electronic modules are arranged on a rear side of the reflector arrangement; - at least one electronic module comprises an electronic unit and a module housing, the electronic unit being arranged in the module housing; - the module housing of the at least one electronic module is made of metal or a metal alloy and comprises a front side, a rear side, end faces and side walls, wherein the front side of the module housing of the at least one electronic module points in the direction of the rear wall of the radome and the rear side of the module housing of the at least one electronic module is opposite the front side of the module housing of the at least one electronic module and points towards the front wall of the radome; - at least the surface of the front side and/or the rear side of the module housing of the at least one electronic module is at least predominantly coated with a heat emission layer which has an emissivity ε, with ε ≥ 0.6.
A method of analyzing a sample comprising a protein of interest, the method comprising: a. denaturing the sample; b. labeling the sample with a fluorescent label to produce a labeled sample; c. quenching un-reacted fluorescent label in the labeled sample; d. deglycosylating the labeled sample with an endoglycosidase; and e. performing electrophoresis on the labeled sample; wherein the sample is denatured, labeled and quenched in steps (a) through (c) prior to deglycosylation in step (d). a. denaturing the sample; b. labeling the sample with a fluorescent label to produce a labeled sample; c. quenching un-reacted fluorescent label in the labeled sample; d. deglycosylating the labeled sample with an endoglycosidase; and e. performing electrophoresis on the labeled sample;
A luer lock connector comprising: a connector body having a distal end, a proximal end, and a gripping portion between the distal end and the proximal end; an intravenous line coupled to the distal end of the connector body; and a luer connector fitting disposed on the proximal end of the body, the luer connector having an outer diameter less than a maximum exterior thickness of the gripping portion of the connector body, characterized in that a substantially flexible material is disposed on at least the outer surface of the gripping portion of the connector body; wherein a substantially rigid material is forming an inner portion of the connector body and forming the luer connector fitting, wherein the rigid material extends through the flexible material to form gripping features. a connector body having a distal end, a proximal end, and a gripping portion between the distal end and the proximal end; an intravenous line coupled to the distal end of the connector body; and a luer connector fitting disposed on the proximal end of the body, the luer connector having an outer diameter less than a maximum exterior thickness of the gripping portion of the connector body, characterized in that a substantially flexible material is disposed on at least the outer surface of the gripping portion of the connector body; wherein a substantially rigid material is forming an inner portion of the connector body and forming the luer connector fitting, wherein the rigid material extends through the flexible material to form gripping features.
A catheter hub assembly comprising: a catheter comprising a second chamber formed as an expandable membrane; a body, a pressure sensor disposed within the body to sense pressure within the catheter and communicating with said body, the body having a first chamber formed therein, the first chamber having a predetermined volume, the body having an opening at one end of the first chamber to the ambient environment; a stopper assembly comprising a push in stopper having an axial bore extending through the stopper, a seal disposed around the stopper, the stopper assembly slideably moveable into the opening, within the first chamber, the seal engaging the body forming a gastight seal within the first chamber and pushing a column of gas ahead of the stopper assembly as the stopper assembly moves from a first position to a second position; the catheter being supported by the stopper assembly; wherein the volume of the first chamber is sufficient to contain a volume of gas to charge the second chamber, wherein the sliding of said stopper assembly from the first position not sealingly engaging the body to the second position sealingly engaging the body, pushing the column of gas ahead of the stopper assembly, charges the second chamber with the volume of gas as the stopper assembly moves to the second position and wherein the catheter is disposed and affixed within said bore, characterised in that the catheter is extending at least along an entire length of said stopper assembly. a catheter comprising a second chamber formed as an expandable membrane; a body, a pressure sensor disposed within the body to sense pressure within the catheter and communicating with said body, the body having a first chamber formed therein, the first chamber having a predetermined volume, the body having an opening at one end of the first chamber to the ambient environment; a stopper assembly comprising a push in stopper having an axial bore extending through the stopper, a seal disposed around the stopper, the stopper assembly slideably moveable into the opening, within the first chamber, the seal engaging the body forming a gastight seal within the first chamber and pushing a column of gas ahead of the stopper assembly as the stopper assembly moves from a first position to a second position; the catheter being supported by the stopper assembly; wherein the volume of the first chamber is sufficient to contain a volume of gas to charge the second chamber, wherein the sliding of said stopper assembly from the first position not sealingly engaging the body to the second position sealingly engaging the body, pushing the column of gas ahead of the stopper assembly, charges the second chamber with the volume of gas as the stopper assembly moves to the second position and wherein the catheter is disposed and affixed within said bore, characterised in that the catheter is extending at least along an entire length of said stopper assembly.
A fuel composition prepared by blending a petroleum derived low sulphur diesel comprising <50 ppm of sulphur with a Fischer-Tropsch derived gasoil and a Fischer-Tropsch derived base oil wherein the amount of the petroleum derived low sulphur diesel is from 60% up to 80% v/v of the total composition; the amount of Fischer-Tropsch derived gasoil is from 10% up to 30% v/v of the total composition; the amount of Fischer-Tropsch derived base oil is from 10% up to 30% v/v of the total composition; the amounts of the Fischer-Tropsch derived gas oil and Fischer-Tropsch derived base oil together being at least 20% v/v of the total composition; and wherein the petroleum derived low sulphur diesel has a density of 0.81 to 0.865 g/cm 3 at 15°C and a kinematic viscosity (ASTM D445) from 1.5 to 4.5 mm 2 /s at 40°C; the Fischer-Tropsch derived gasoil has a density of 0.76 to 0.80 g/cm 3 at 15°C and a kinematic viscosity (ASTM D445) from 2.0 to 4.5 mm 2 /s at 40°C; the Fischer-Tropsch derived base oil has a density of 0.79 to 0.82 g/cm 3 at 15°C and a kinematic viscosity (ASTM D445) from 7.5 to 12.0 mm 2 /s at 40°C; and wherein the composition has increased power performance in a diesel engine when compared to fuel compositions comprising only a petroleum derived low sulphur diesel comprising <50 ppm of sulphur and a Fischer-Tropsch derived gasoil.
A method for removing large protein aggregate impurities from a biological product of interest, the method comprising steps of: pretreating a hydrophobic membrane filter with a surfactant solution having a mass concentration in the range of 0.01 to 10 %w/v surfactant so as to provide a pretreated membrane filter; and, filtering a fluid comprising a biological product through the pretreated membrane filter so as to obtain a filtrate comprising the biological product; wherein the membrane filter has a pore size sufficient to retain large protein aggregate impurities present in the fluid; and, wherein a higher yield of recovery of the biological product in the filtrate is achieved as compared to a non-pretreated control; wherein the biological product is or comprises a protein, a virus-like particle, a viral particle, a virion, or any combination thereof. pretreating a hydrophobic membrane filter with a surfactant solution having a mass concentration in the range of 0.01 to 10 %w/v surfactant so as to provide a pretreated membrane filter; and, filtering a fluid comprising a biological product through the pretreated membrane filter so as to obtain a filtrate comprising the biological product; wherein the membrane filter has a pore size sufficient to retain large protein aggregate impurities present in the fluid; and, wherein a higher yield of recovery of the biological product in the filtrate is achieved as compared to a non-pretreated control; wherein the biological product is or comprises a protein, a virus-like particle, a viral particle, a virion, or any combination thereof. wherein the membrane filter has a pore size sufficient to retain large protein aggregate impurities present in the fluid; and, wherein a higher yield of recovery of the biological product in the filtrate is achieved as compared to a non-pretreated control; wherein the biological product is or comprises a protein, a virus-like particle, a viral particle, a virion, or any combination thereof.
A compound of formula or a pharmaceutically acceptable salt, solvate or polymorph thereof, wherein Y is (C 1-4) alkylene, R 1 is selected from the group consisting of imidazolyl, pyrazolyl, pyrrolyl, furyl, oxadiazolyl, oxazolyl, and pyrimidyl each of which is optionally substituted by one or more substituents independently selected from halogen, hydroxyl, C 1-6 alkyl, C 1-4 alkoxy or C 3-6 cycloalkyl and R 2 is an aryl 2 or a heterocyclyl; wherein the term aryl 2 includes phenyl, naphtyl, anthracenyl and phenanthrenyl, and is optionally substituted by one or more substituents independently selected from hydroxyl, C 1-6 alkyl, C 1-4 alkoxy, trifluoromethyl, CO 2 R 3, halogen, hydroxyl- C 1-4 alkyl-, NR 6 R 7, C R 6, C NR 6 R 7, C 1-4 alkyl-diethoxyphosphoryl or C 1-4 alkyl-phosphonic acid, whereby R 3 is selected from H and C 1-6 alkyl, and R 6 and R 7 are each independently selected from H, C 1-6 -alkyl and C 1-4 alkoxy; and wherein the term heterocyclyl refers to tetrahydropyran and heteroaryl 2. The term heteroaryl 2 includes pyridyl, tetrahydroisoquinolinyl, imidazopyridinyl, quinolinyl, isoquinolinyl, pyrazinyl, pyrimidyl, naphtyridinyl, pyridazinyl, benzimidazolyl, benzothiazolyl, pyrazolyl, thiazolyl, imidazolyl, indazolyl. Heteroaryl 2 is optionally substituted by one or more substituents independently selected from halogen, hydroxyl, C 1-6 alkyl, C 1-4 alkoxy, oxy-C 1-4 alkylamine or pyrrolidinyl-methanone.
An apparatus for automatically dispensing a teeth whitening substance, the apparatus comprising: a fluid reservoir configured to receive the teeth whitening substance; a nozzle having an output port; a fluid dispenser coupled between the fluid reservoir and the nozzle, wherein the fluid dispenser is configured to dispense the teeth whitening substance from the fluid reservoir to the nozzle, wherein the teeth whitening substance is output via the output port; a sensor positioned for viewing in an advance dispensing direction of the nozzle, wherein the sensor is configured to sense a target surface that comprises either (i) a tooth surface or (ii) a surface other than the tooth surface in the advance dispensing direction of the nozzle; and a controller operatively coupled between the sensor and the fluid dispenser for (i) controlling a gating of the fluid dispenser to dispense the teeth whitening substance from the fluid reservoir in response to the sensor detecting the tooth surface, and (ii) stopping or disabling the gating of the fluid dispenser to stop or disable a dispensing of the teeth whitening substance from the fluid reservoir in response to the sensor detecting the surface other than a tooth surface. a fluid reservoir configured to receive the teeth whitening substance; a nozzle having an output port; a fluid dispenser coupled between the fluid reservoir and the nozzle, wherein the fluid dispenser is configured to dispense the teeth whitening substance from the fluid reservoir to the nozzle, wherein the teeth whitening substance is output via the output port; a sensor positioned for viewing in an advance dispensing direction of the nozzle, wherein the sensor is configured to sense a target surface that comprises either (i) a tooth surface or (ii) a surface other than the tooth surface in the advance dispensing direction of the nozzle; and a controller operatively coupled between the sensor and the fluid dispenser for (i) controlling a gating of the fluid dispenser to dispense the teeth whitening substance from the fluid reservoir in response to the sensor detecting the tooth surface, and (ii) stopping or disabling the gating of the fluid dispenser to stop or disable a dispensing of the teeth whitening substance from the fluid reservoir in response to the sensor detecting the surface other than a tooth surface.
A guide vane intended to be arranged in all or part of an air flow of a bypass aircraft turbomachine fan, the guide vane comprising a root, a tip as well as an aerodynamic flow straightening part arranged between the root and the tip of the vane, said aerodynamic part of the vane including a first lubricant cooling interior passage in which heat transfer means are arranged, the first interior passage extending along a first main flowing direction of the lubricant from the root to the tip of the vane, said first interior passage being partly delimited by an intrados wall and an extrados wall of the vane, the aerodynamic part also including a second lubricant cooling interior passage in which heat transfer means are arranged, the second interior passage extending along a second main flowing direction of the lubricant from the tip to the root of the vane, said second interior passage being partly delimited by the intrados wall and the extrados wall of the vane, and characterized in that the aerodynamic part comprises a bent area connecting one end (50a1) of the first interior passage to one end (50b1) of the second passage, the bent area extending along a curved generatrix and being partly delimited by the intrados wall and the extrados wall of the vane, and in that the bent area comprises at least one lubricant guide arranged between the intrados wall and the extrados wall of the vane, and each extending substantially parallel to the curved generatrix of the bent area.
The use of lamellar fillers in a composition of a seal which may notably be used in a timepiece, for obtaining a permeability to helium or hydrogen gas of said seal of less than 5.10 -17 m 2 Pa -1 s -1, said seal including at least one elastomer, between 50 and 100 parts by weight of a mixture of carbon black, silica and organosilane, and between 50 and 60 parts by weight of lamellar fillers, 100 parts by weight of said elastomer.
A method for accelerating load flow for integrated volt/var control (IVVC) optimization, comprising: evaluating load flow on lines of an electrical network by calculating operating conditions for all lines in the network, the operating conditions comprising at least a voltage drop and a power loss. identifying combinable network lines, wherein identifying combinable network lines includes identifying lines of the electrical network that have a power loss below a predetermined threshold; generating a simplified network model by combining identified combinable lines including eliminating the identified lines having a power loss below a predetermined threshold and combining the end buses thereof together; and determining load flow optimization for IVVC based at least in part on the simplified network model. evaluating load flow on lines of an electrical network by calculating operating conditions for all lines in the network, the operating conditions comprising at least a voltage drop and a power loss. identifying combinable network lines, wherein identifying combinable network lines includes identifying lines of the electrical network that have a power loss below a predetermined threshold; generating a simplified network model by combining identified combinable lines including eliminating the identified lines having a power loss below a predetermined threshold and combining the end buses thereof together; and determining load flow optimization for IVVC based at least in part on the simplified network model.
A High Electron Mobility Transistor, HEMT, semiconductor structure (10, 40), comprising: a substrate (12, 42); a nucleation layer (14, 44) on the substrate; a Group III-N buffer layer (16, 46) on the nucleation layer; and a Group III-N barrier layer (18, 48) in direct contact with the Group III-N buffer layer (16, 46) to form a junction between the Group III-N buffer layer and the Group III-N barrier layer, the Group III-N buffer layer having a band gap lower than the Group III-N barrier layer producing a two dimensional electron gas, 2DEG, channel in the Group III-N buffer layer; wherein the Group III-N barrier layer consists of a 1.5nm thick lower portion (18a, 48a) and an upper portion (18b, 48b) both extending from a source electrode to a drain electrode of the HEMT; wherein the entire upper portion (18b, 48b) of the barrier layer is doped with a dopant with a doping concentration in excess of 1×10 17 atoms per cm 3 and wherein the lower portion (18a, 48a) of the barrier layer closest to the 2DEG channel has doping concentration levels of 5 × 10 16 atoms per cm 3 or less, wherein the dopant is carbon, beryllium, chromium, vanadium, magnesium, zinc or iron, and wherein the barrier layer is AlGaN and the buffer layer is GaN. a substrate (12, 42); a nucleation layer (14, 44) on the substrate; a Group III-N buffer layer (16, 46) on the nucleation layer; and a Group III-N barrier layer (18, 48) in direct contact with the Group III-N buffer layer (16, 46) to form a junction between the Group III-N buffer layer and the Group III-N barrier layer, the Group III-N buffer layer having a band gap lower than the Group III-N barrier layer producing a two dimensional electron gas, 2DEG, channel in the Group III-N buffer layer; wherein the dopant is carbon, beryllium, chromium, vanadium, magnesium, zinc or iron, and wherein the barrier layer is AlGaN and the buffer layer is GaN.