Design method of an orthopedic support suitable for being applied on a part of the body of a patient; said method comprising the following steps: - step of determination of the part of the body where said orthopedic support is to be applied; - step of identification of a generic 3D model in a 3D model database relative to the part of the patient's body where the orthopedic support is to be applied; - step of acquisition of a 3D image of the part of the patient's body where said orthopedic support is to be applied, by means of 3D image acquisition means; - step of detection of biometric data of the part of the patient's body where said orthopedic support is to be applied; - step of modeling of the generic 3D model; said modeling of the generic 3D model providing for a step of merging wherein the generic 3D model is merged with the 3D image in such a way to obtain a 3D model that is modelized according to the morphology of the part of the patient's body; said modeling also providing for a as step of dimensioning wherein the modelized 3D model is redimensioned according to the biometric data detected in the step of detection, in such a way to obtain a 3D digital prototype of the orthopedic support wherein each generic 3D model stored in the 3D model database comprises a plurality of base units that are joined one to another; wherein, in said step of dimensioning of said step of modeling, each base unit of the generic 3D model is redimensioned according to the biometric data detected in the step of detection; and characterised in that said base units of the generic 3D model are disposed in such a way to define separation lines between adjacent base units that coincide with stress lines and breakage lines of the generic 3D model. - step of determination of the part of the body where said orthopedic support is to be applied; - step of identification of a generic 3D model in a 3D model database relative to the part of the patient's body where the orthopedic support is to be applied; - step of acquisition of a 3D image of the part of the patient's body where said orthopedic support is to be applied, by means of 3D image acquisition means; - step of detection of biometric data of the part of the patient's body where said orthopedic support is to be applied; - step of modeling of the generic 3D model; said modeling of the generic 3D model providing for a step of merging wherein the generic 3D model is merged with the 3D image in such a way to obtain a 3D model that is modelized according to the morphology of the part of the patient's body; said modeling also providing for a as step of dimensioning wherein the modelized 3D model is redimensioned according to the biometric data detected in the step of detection, in such a way to obtain a 3D digital prototype of the orthopedic support wherein each generic 3D model stored in the 3D model database comprises a plurality of base units that are joined one to another; wherein, in said step of dimensioning of said step of modeling, each base unit of the generic 3D model is redimensioned according to the biometric data detected in the step of detection; and characterised in that said base units of the generic 3D model are disposed in such a way to define separation lines between adjacent base units that coincide with stress lines and breakage lines of the generic 3D model.