mhurhangee/ep-ind-claims huggingface dataset:
A computer-implemented method for predicting a concentration of an in vivo analyte, the method comprising: obtaining a plurality of in vivo spectra of the in vivo analyte; determining a learning section of a concentration predicting algorithm for the in vivo analyte based on an unchanged section, during which a concentration of the in vivo analyte is not substantially changed, and the in vivo spectra; and predicting the concentration of the in vivo analyte by using the concentration predicting algorithm based on a learned result of the learning section and an intrinsic spectrum of the in vivo analyte, characterized in that, the determining of the learning section comprises: calculating a similarity between the in vivo spectra; determining a section having a high similarity as a similar section; and determining a section, during which the unchanged section and the similar section overlap each other, as the learning section. obtaining a plurality of in vivo spectra of the in vivo analyte; determining a learning section of a concentration predicting algorithm for the in vivo analyte based on an unchanged section, during which a concentration of the in vivo analyte is not substantially changed, and the in vivo spectra; and predicting the concentration of the in vivo analyte by using the concentration predicting algorithm based on a learned result of the learning section and an intrinsic spectrum of the in vivo analyte, characterized in that, the determining of the learning section comprises: calculating a similarity between the in vivo spectra; determining a section having a high similarity as a similar section; and determining a section, during which the unchanged section and the similar section overlap each other, as the learning section. calculating a similarity between the in vivo spectra; determining a section having a high similarity as a similar section; and determining a section, during which the unchanged section and the similar section overlap each other, as the learning section.
Operator control device for controlling functions of a motor vehicle, having an operator control element which can be moved out of a position of rest, beyond a first activation position into a second activation position, wherein the operator control device is configured to output feedback, which can be perceived in a tactile fashion, in at least the second activation position of the operator control element, and having a control unit which is configured to trigger a function to which the operator control element is assigned if the operator control element is arranged in the second activation position, characterized in that the control unit is configured to actuate, in accordance with the function, a display device to display information associated with the function, if the operator control element is arranged in the first activation position, wherein the operator control device is configured to output feedback, which can be perceived in a tactile fashion, in the first activation position of the operator control element, wherein the control unit is oriented to actuate an actuator, which acts on the operator control element, to output the feedback which can be perceived in a tactile fashion.
A non-burning type flavor inhaler configured to generate an aerosol atomized by an atomizer comprising a heat source without burning, comprising: a power source configured to supply power to the heat source; a light-emitting element; and a controller configured to control the light-emitting element, characterized in that the controller controls the light-emitting element in a predetermined light-emitting mode in a non-puff state not inhaling the aerosol, wherein the predetermined light-emitting mode comprises; a first predetermined light-emitting mode applied until a number of puff reaches a certain number which is three or more, a second predetermined light-emitting mode applied after the number of puff exceeds the certain number, and the first predetermined light-emitting mode is different from the second predetermined light-emitting mode. a power source configured to supply power to the heat source; a light-emitting element; and a controller configured to control the light-emitting element, characterized in that the controller controls the light-emitting element in a predetermined light-emitting mode in a non-puff state not inhaling the aerosol, wherein the predetermined light-emitting mode comprises; a first predetermined light-emitting mode applied until a number of puff reaches a certain number which is three or more, a second predetermined light-emitting mode applied after the number of puff exceeds the certain number, and the first predetermined light-emitting mode is different from the second predetermined light-emitting mode.
Cargo bicycle comprising a frame (1, 2) having a front frame part and a rear frame part, and a receiving element (4, 5) for receiving loads, the two frame parts (1, 2) being designed to be movable relative to one another in the longitudinal direction such that the length of the cargo bicycle is variable, the receiving element (4, 5) having a front receiving element part which is immovably connected to the front frame part and is movably connected to the rear frame part by means of the front frame part, and the receiving element (4, 5) having a rear receiving element part which is immovably connected to the rear frame part and is movably connected to the front frame part by means of the rear frame part, such that the length of the receiving element (4, 5) is variable due to the mobility of the two frame parts (1; 2) with respect to one another, characterized in that the front receiving element part has a bottom element and the rear receiving element part has a bottom element, the bottom element of the front receiving element part being arranged above the bottom element of the rear receiving element part, or vice versa.
A method of producing cellulase comprising the following steps of to: the step of subjecting an aqueous solution of cellulase derived from filamentous fungi to filtration through an ultrafiltration membrane with a molecular weight cut off of 100,000 to 200,000 to obtain a filtrate and to concurrently obtain a concentrated enzyme liquid as a retentate; the step of further subjecting the filtrate obtained in the step to filtration through a second ultrafiltration membrane with a molecular weight cut off of 5,000 to 50,000 to obtain a second concentrated enzyme liquid as a retentate; and the step of mixing the concentrated enzyme liquid obtained in the steps of and to obtain cellulase derived from filamentous fungi. the step of subjecting an aqueous solution of cellulase derived from filamentous fungi to filtration through an ultrafiltration membrane with a molecular weight cut off of 100,000 to 200,000 to obtain a filtrate and to concurrently obtain a concentrated enzyme liquid as a retentate; the step of further subjecting the filtrate obtained in the step to filtration through a second ultrafiltration membrane with a molecular weight cut off of 5,000 to 50,000 to obtain a second concentrated enzyme liquid as a retentate; and the step of mixing the concentrated enzyme liquid obtained in the steps of and to obtain cellulase derived from filamentous fungi.
Office or conference seating furniture such as for example an office swivel chair, having a backrest and having armrests that are coupled to a seat carrier, and having a connecting arrangement comprising: a backrest structural element, which forms a supporting part of the backrest, a crossbeam element, which the seat carrier is coupled to, a radial bearing via which the backrest structural element is rotatably coupled perpendicular to a transverse direction to the crossbeam element, and a connecting section, which connects the crossbeam element to the backrest structural element and which is arranged and embodied in such a manner that the backrest structural element may move relative to the crossbeam element in a resilient elastic manner, wherein the connecting section is formed in an integral manner from an elastomer material. a backrest structural element, which forms a supporting part of the backrest, a crossbeam element, which the seat carrier is coupled to, a radial bearing via which the backrest structural element is rotatably coupled perpendicular to a transverse direction to the crossbeam element, and a connecting section, which connects the crossbeam element to the backrest structural element and which is arranged and embodied in such a manner that the backrest structural element may move relative to the crossbeam element in a resilient elastic manner, wherein the connecting section is formed in an integral manner from an elastomer material.
A method for the preparation of sulfated cellulose ethers, with the following steps: a) dissolving at least one cellulose ether in a polar aprotic solvent, b) adding a sulfating agent to the solution of the cellulose ether, wherein the sulfating takes place at a temperature of -10 to 150°C, c) precipitating the sulfated intermediate product in a precipitation medium containing water, at least one alcohol and at least one sodium salt, d) washing and drying the precipitation product, with a cellulose ether sulfate being obtained. a) dissolving at least one cellulose ether in a polar aprotic solvent, b) adding a sulfating agent to the solution of the cellulose ether, wherein the sulfating takes place at a temperature of -10 to 150°C, c) precipitating the sulfated intermediate product in a precipitation medium containing water, at least one alcohol and at least one sodium salt, d) washing and drying the precipitation product, with a cellulose ether sulfate being obtained.
Composition comprising a compound of formula A-B, wherein A is a pancreatic βcell targeting moiety, and B is an inhibitor of expression and/or activity of Apolipoprotein CIII (apoCIII), and/or of β1 integrin for use in treating or limiting development of diabetes in a subject.
A system for processing fluids, comprising: an elongated vessel defining an inner chamber having a fluid inlet and a rotatable shaft through the vessel, wherein said elongated vessel and rotatable shaft are oriented horizontally; means for centrifugally and axially compressing a fluid through the vessel, wherein the means for centrifugally and axially compressing comprises a proximate set of alternately spaced trays and baffles, the trays attached to the shaft and having a plurality of scoops through which the fluid passes, the baffles attached to the vessel and having a plurality of apertures through which the fluid passes, wherein each of the plurality of scoops and plurality of apertures have an inlet (52, 62) of a first diameter and an outlet (54, 64) of a second smaller diameter; means (30, 32, 34) for rotating the shaft to drive the means for centrifugally and axially compressing; a means for axially pumping the fluid through the vessel comprising an intake chamber disposed between the fluid inlet and the means for centrifugally and axially compressing, wherein the intake chamber functions as an axial pump once the system is run to an operating rotation speed; and a fluid outlet on the vessel characterized in that the baffles extend from the wall of the vessel through the chamber and end proximate to the shaft leaving a central opening between the baffles and the shaft and the trays are affixed to the shaft and have scoops disposed therethrough. an elongated vessel defining an inner chamber having a fluid inlet and a rotatable shaft through the vessel, wherein said elongated vessel and rotatable shaft are oriented horizontally; means for centrifugally and axially compressing a fluid through the vessel, wherein the means for centrifugally and axially compressing comprises a proximate set of alternately spaced trays and baffles, the trays attached to the shaft and having a plurality of scoops through which the fluid passes, the baffles attached to the vessel and having a plurality of apertures through which the fluid passes, wherein each of the plurality of scoops and plurality of apertures have an inlet (52, 62) of a first diameter and an outlet (54, 64) of a second smaller diameter; means (30, 32, 34) for rotating the shaft to drive the means for centrifugally and axially compressing; a means for axially pumping the fluid through the vessel comprising an intake chamber disposed between the fluid inlet and the means for centrifugally and axially compressing, wherein the intake chamber functions as an axial pump once the system is run to an operating rotation speed; and a fluid outlet on the vessel
A vapour-generating system, comprising: a housing comprising an air inlet, an air outlet, and an airflow passage extending therebetween; a reservoir holding an aerosol-generating substrate; and a heating assembly, comprising: a heating element; and a capillary material, one side of the capillary material being in fluidic communication with the heating element, an opposite side of the capillary material being in fluidic communication with the reservoir so as to transport the aerosol-generating substrate to the heating element by capillary action, wherein the heating element is configured to heat the aerosol-generating substrate therein to generate a vapour, and wherein the heating assembly comprises at least one mesh, the at least one mesh having an aperture size of zero whereby when wires or filaments of the mesh are projected along a line normal to the mesh onto a two-dimensional flat plane, there is no open space visible between the two-dimensional projections of the wires or filaments, so as to inhibit transmission of particles in the aerosol-generating substrate into the airflow passage. a housing comprising an air inlet, an air outlet, and an airflow passage extending therebetween; a reservoir holding an aerosol-generating substrate; and a heating assembly, comprising: a heating element; and a capillary material, one side of the capillary material being in fluidic communication with the heating element, an opposite side of the capillary material being in fluidic communication with the reservoir so as to transport the aerosol-generating substrate to the heating element by capillary action, a heating element; and a capillary material, one side of the capillary material being in fluidic communication with the heating element, an opposite side of the capillary material being in fluidic communication with the reservoir so as to transport the aerosol-generating substrate to the heating element by capillary action, wherein the heating element is configured to heat the aerosol-generating substrate therein to generate a vapour, and wherein the heating assembly comprises at least one mesh, the at least one mesh having an aperture size of zero whereby when wires or filaments of the mesh are projected along a line normal to the mesh onto a two-dimensional flat plane, there is no open space visible between the two-dimensional projections of the wires or filaments, so as to inhibit transmission of particles in the aerosol-generating substrate into the airflow passage.
An electrochemical hydrogen compressor comprising: a cell including a proton conductive electrolyte membrane having a pair of principal surfaces, a cathode disposed on a first one of the principal surfaces of the electrolyte membrane, and an anode disposed on a second one of the principal surfaces of the electrolyte membrane; a voltage applicator configured to apply a voltage between the anode and the cathode; a dew point adjuster configured to adjust a dew point of a hydrogen-containing gas to be supplied to the anode; and a controller, characterized in that when the temperature of the cell increases, the controller is configured to control the dew point adjuster to increase the dew point of the hydrogen-containing gas. a cell including a proton conductive electrolyte membrane having a pair of principal surfaces, a cathode disposed on a first one of the principal surfaces of the electrolyte membrane, and an anode disposed on a second one of the principal surfaces of the electrolyte membrane; a voltage applicator configured to apply a voltage between the anode and the cathode; a dew point adjuster configured to adjust a dew point of a hydrogen-containing gas to be supplied to the anode; and a controller, characterized in that when the temperature of the cell increases, the controller is configured to control the dew point adjuster to increase the dew point of the hydrogen-containing gas.
A fitting comprising a first fitting member and a second fitting member articulated to said first fitting member and detachably or non-detachably connected thereto, with one of said fitting members (20; 10) having retarding means coupled thereto, said retarding means comprising an activating element coupled therewith and comprising a piston-cylinder unit of which the activating element is a piston rod, with the fitting comprising an actuating element pivotable relative to the fitting member (20; 10) supporting the retarding means and articulated to or rigidly connected with the respective other fitting member (10; 20), and with fitting comprising a transmission means arranged on the fitting member (20; 10) supporting the retarding means, characterized in that - the transmission means converts the pivoting movement of the actuating element into a translatory movement of at least one part (76; 77; 79) of the transmission means; in that - the at least one, translatorily moved part (76; 77; 79) of the transmission means is guided by guide means in a direction parallel to the activating element; and in that - the at least one, translatorily moved part (76; 77; 79) actuates the retarding means directly or indirectly. - the transmission means converts the pivoting movement of the actuating element into a translatory movement of at least one part (76; 77; 79) of the transmission means; in that - the at least one, translatorily moved part (76; 77; 79) of the transmission means is guided by guide means in a direction parallel to the activating element; and in that - the at least one, translatorily moved part (76; 77; 79) actuates the retarding means directly or indirectly.
A drug conjugate comprising an amphiphilic peptide and a hydrophobic drug selectively activated by cathepsin B in tumor cells and spontaneously forming spherical nanoparticles in a solvent, wherein the amphiphilic peptide is represented by n -F-R-R- m (n=0-5, m=1-5), wherein the hydrophobic drug is selected from the group consisting of taxol, bendamustine, busulfan, carmustine, chlorambucil, cyclophosphamide, dacarbazine, adriamycin, daunomycin, ifosfamide, melphalan, procarbazine, streptozocin, temozolomide, asparaginase, capecitabine, cytarabine, 5-fluorouracil, fludarabine, gemcitabine, methotrexate, pemetrexed, raltitrexed, actinomycin-D, bleomycin, daunorubicin, doxorubicin, pegylated liposomal doxorubicin, epirubicin, idarubicin, mitomycin, mitoxantrone, etoposide, docetaxel, irinotecan, paclitaxel, topotecan, vinblastine, vincristine, vinorelbine, carboplatin, cisplatin, oxaliplatin, alemtuzumab, BCG, bevacizumab, cetuximab, denosumab, erlotinib, gefitinib, imatinib, interferon, ipilimumab, lapatinib, panitumumab, rituximab, sunitinib, sorafenib, temsirolimus, trastuzumab, clodronate, ibandronic acid, pamidronate, and zoledronic acid.
An electroconductive member for electrophotography, comprising, in this order: an electroconductive support; an electroconductive elastic layer; and a surface layer, wherein: the surface layer contains a binder resin; and electroconductive fine particles which are dispersed in the binder resin and have a number average particle diameter of 5.0 nm or more and 50.0 nm or less; at least part of the electroconductive fine particles are exposed from the surface layer; the surface layer has, on a surface thereof, protruded portions derived from exposed portions of the electroconductive fine particles; the surface layer has a volume resistivity of 1.0×10 10 Ω•cm or more and 1.0×10 16 Ω•cm or less, the volume resistivity being measured as described in the description and the surface layer has a universal hardness at a depth of 1 μm from the surface thereof of 1.0 N/mm 2 or more and 7.0 N/mm 2 or less, the universal hardness being measured as described in the description. an electroconductive support; an electroconductive elastic layer; and a surface layer, the surface layer contains a binder resin; and electroconductive fine particles which are dispersed in the binder resin and have a number average particle diameter of 5.0 nm or more and 50.0 nm or less; a binder resin; and electroconductive fine particles which are dispersed in the binder resin and have a number average particle diameter of 5.0 nm or more and 50.0 nm or less; at least part of the electroconductive fine particles are exposed from the surface layer; the surface layer has, on a surface thereof, protruded portions derived from exposed portions of the electroconductive fine particles; the surface layer has a volume resistivity of 1.0×10 10 Ω•cm or more and 1.0×10 16 Ω•cm or less, the volume resistivity being measured as described in the description and the surface layer has a universal hardness at a depth of 1 μm from the surface thereof of 1.0 N/mm 2 or more and 7.0 N/mm 2 or less, the universal hardness being measured as described in the description.
An earpiece comprising: a body comprising an acoustic passage for conducting sound waves to an ear canal of a user of the earpiece; a retaining structure configured to engage with external structural features, including the concha and/or the anti-helix, of an ear of the user to hold the body in position; a movable joint structure to couple the body to the retaining structure, the movable joint structure being configured to allow angular motion of the body with respect to the retaining structure along a plane perpendicular to an axis of the angular motion; wherein the body is arranged to be inserted partially into the ear canal under the tragus, and adapted to rotate, with respect to the axis, towards an exterior opening of the ear canal of the user when the retaining structure engages with the concha and/or the anti-helix of the user. a body comprising an acoustic passage for conducting sound waves to an ear canal of a user of the earpiece; a retaining structure configured to engage with external structural features, including the concha and/or the anti-helix, of an ear of the user to hold the body in position; a movable joint structure to couple the body to the retaining structure, the movable joint structure being configured to allow angular motion of the body with respect to the retaining structure along a plane perpendicular to an axis of the angular motion; wherein the body is arranged to be inserted partially into the ear canal under the tragus, and adapted to rotate, with respect to the axis, towards an exterior opening of the ear canal of the user when the retaining structure engages with the concha and/or the anti-helix of the user.
Apparatus for determining chest compression during CPR, the apparatus comprising: an accelerometer configured to be applied to the chest of a patient at a location near or at the location at which a rescuer applies force to produce chest compressions; processing circuitry configured to determine chest displacement from analysis of features of an acceleration waveform produced by the accelerometer, characterized in that the processing circuitry is configured to decide from the analysis of features of the acceleration waveform whether or not a rescuer has sufficiently released the patient's chest. an accelerometer configured to be applied to the chest of a patient at a location near or at the location at which a rescuer applies force to produce chest compressions; processing circuitry configured to determine chest displacement from analysis of features of an acceleration waveform produced by the accelerometer, characterized in that the processing circuitry is configured to decide from the analysis of features of the acceleration waveform whether or not a rescuer has sufficiently released the patient's chest.