A sole structure for an article of footwear having a heel region, a mid-foot region, a forefoot region, an interior region, and a peripheral region, the sole structure comprising: a foam element extending from the forefoot region to the heel region and having an upper surface and a lower surface formed on an opposite side of the foam element from the upper surface, the foam element including a recess formed in the lower surface in the forefoot region and a peripheral groove formed in the lower surface and spaced apart from the recess, the peripheral groove extending from a first end in the forefoot region on the medial side and around the heel region to a second end in the mid-foot region on the lateral side; a posterior cushioning arrangement disposed within the peripheral groove and extending along the peripheral region of the sole structure from the heel region to the mid-foot region; and an anterior cushioning arrangement (i) disposed in the recess of the foam element, (ii) spaced apart from and free of the posterior cushioning arrangement, and (iii) having a proximal end adjacent to the lower surface of the foam element and a distal end formed on an opposite side of the anterior cushioning arrangement than the proximal end, the anterior cushioning arrangement including at least one medial bladder proximate to a medial side of the sole structure and at least one lateral bladder proximate to a lateral side of the sole structure and spaced apart and free from the at least one medial bladder. a foam element extending from the forefoot region to the heel region and having an upper surface and a lower surface formed on an opposite side of the foam element from the upper surface, the foam element including a recess formed in the lower surface in the forefoot region and a peripheral groove formed in the lower surface and spaced apart from the recess, the peripheral groove extending from a first end in the forefoot region on the medial side and around the heel region to a second end in the mid-foot region on the lateral side; a posterior cushioning arrangement disposed within the peripheral groove and extending along the peripheral region of the sole structure from the heel region to the mid-foot region; and an anterior cushioning arrangement (i) disposed in the recess of the foam element, (ii) spaced apart from and free of the posterior cushioning arrangement, and (iii) having a proximal end adjacent to the lower surface of the foam element and a distal end formed on an opposite side of the anterior cushioning arrangement than the proximal end, the anterior cushioning arrangement including at least one medial bladder proximate to a medial side of the sole structure and at least one lateral bladder proximate to a lateral side of the sole structure and spaced apart and free from the at least one medial bladder. (i) disposed in the recess of the foam element, (ii) spaced apart from and free of the posterior cushioning arrangement, and (iii) having a proximal end adjacent to the lower surface of the foam element and a distal end formed on an opposite side of the anterior cushioning arrangement than the proximal end, the anterior cushioning arrangement including at least one medial bladder proximate to a medial side of the sole structure and at least one lateral bladder proximate to a lateral side of the sole structure and spaced apart and free from the at least one medial bladder.