mhurhangee/ep-ind-claims huggingface dataset:
A T cell genetically modified to express a CAR wherein the CAR comprises (a) an antigen binding domain that is an anti-CD19 scFv (b) a costimulatory 4-1BB signaling region, and (c) a CD3 zeta signaling domain for use in a method for treating cancer in a human, wherein the anti-CD19 scFv comprises the amino acid sequence of SEQ ID NO:20 and/or the CD3 zeta signaling domain comprises the amino acid sequence of SEQ ID NO:24, and wherein the human is resistant to at least one chemotherapeutic agent.
An electronic device, comprising: a display module; an input module; a moving mechanism, comprising: a torsion hinge, having a first plate disposed on the input module and a second plate rotatable relative to the first plate, wherein the second plate has a slot portion; a fixed member, mounted on the second plate; a slider, fixed to the display module and slidable relative to the fixed member; a lock member, rotatable relative to the first plate and disposed inside the input module, wherein when the moving mechanism is in a closed state, the lock member is in an initial position and engaged with the slot portion of the second plate to restrict the second plate in a predetermined angle; and an elastic member disposed on the slider, wherein when the slider moves relative to the fixed member to a critical position, the elastic member is adapted to protrude into the input module and to push the lock member to release from the slot portion, such that the second plate is rotatable relative to the first plate to an open position. a display module; an input module; a moving mechanism, comprising: a torsion hinge, having a first plate disposed on the input module and a second plate rotatable relative to the first plate, wherein the second plate has a slot portion; a fixed member, mounted on the second plate; a slider, fixed to the display module and slidable relative to the fixed member; a lock member, rotatable relative to the first plate and disposed inside the input module, wherein when the moving mechanism is in a closed state, the lock member is in an initial position and engaged with the slot portion of the second plate to restrict the second plate in a predetermined angle; and an elastic member disposed on the slider, wherein when the slider moves relative to the fixed member to a critical position, the elastic member is adapted to protrude into the input module and to push the lock member to release from the slot portion, such that the second plate is rotatable relative to the first plate to an open position. a torsion hinge, having a first plate disposed on the input module and a second plate rotatable relative to the first plate, wherein the second plate has a slot portion; a fixed member, mounted on the second plate; a slider, fixed to the display module and slidable relative to the fixed member; a lock member, rotatable relative to the first plate and disposed inside the input module, wherein when the moving mechanism is in a closed state, the lock member is in an initial position and engaged with the slot portion of the second plate to restrict the second plate in a predetermined angle; and an elastic member disposed on the slider, wherein when the slider moves relative to the fixed member to a critical position, the elastic member is adapted to protrude into the input module and to push the lock member to release from the slot portion, such that the second plate is rotatable relative to the first plate to an open position.
Vibration absorber for damping vibrations which occur in machines, installations and buildings, comprising at least one pendulum cable or pendulum rod with a pendulum weight and at least one magnetic damper, characterised in that the magnetic damper is rotationally symmetrical and comprises the following components: (i) a damper tube made from a non-magnetisable conductive material, (ii) a support device, which is rotationally symmetrical around the longitudinal axis of the damper, is provided with attachment means and has at least one outer, in relation to the damper tube, magnetic ring arrangement comprising one or more permanent magnets or comprising one or more electromagnets in the form of coils, which are arranged in such a way that north and south poles of the said magnets point either radially inwards or radially outwards in relation to the longitudinal axis of the tube of the magnetic damper, where the at least one magnetic outer ring has been pushed over the damper tube, and ring and tube are movable relative to one another in a non-contact and friction-free manner, and the separation between the at least one magnetic ring and the outside surface of the damper tube is ≥ 0.1 mm and ≤ 2.0 mm, and (iii) at least one ring consisting of a ferromagnetic material or segments composed thereof, which immediately surrounds the at least one magnetic outer ring. (i) a damper tube made from a non-magnetisable conductive material, (ii) a support device, which is rotationally symmetrical around the longitudinal axis of the damper, is provided with attachment means and has at least one outer, in relation to the damper tube, magnetic ring arrangement comprising one or more permanent magnets or comprising one or more electromagnets in the form of coils, which are arranged in such a way that north and south poles of the said magnets point either radially inwards or radially outwards in relation to the longitudinal axis of the tube of the magnetic damper, where the at least one magnetic outer ring has been pushed over the damper tube, and ring and tube are movable relative to one another in a non-contact and friction-free manner, and the separation between the at least one magnetic ring and the outside surface of the damper tube is ≥ 0.1 mm and ≤ 2.0 mm, and (iii) at least one ring consisting of a ferromagnetic material or segments composed thereof, which immediately surrounds the at least one magnetic outer ring.
A mission critical, push to talk, MCPTT, server comprising: a transceiver configured to receive a call request for a MCPTT call, from a MCPTT user equipment initiating a MCPTT call towards a GSM-R user equipment, wherein the call request includes the MCPTT identifier of the MCPTT user equipment; and a processor configured to access, in response to receiving the call request, a mapping of the MCPTT identifier of the MCPTT user equipment with an interworking identifier that is formed according to an address format implemented in Global System for Mobile communications, GSM, for Railways, GSM-R, wherein the processor is configured to obtain, by means of the mapping, the interworking identifier corresponding to the MCPTT identifier of the MCPTT user equipment, and to add the interworking identifier to the call request; wherein the transceiver is configured to forward the call request to an interworking function associated with the GSM-R system, characterized in that the mapping is stored in a user profile that includes a binding between the MCPTT identifier, the interworking identifier, and an identifier of the MCPTT server. a transceiver configured to receive a call request for a MCPTT call, from a MCPTT user equipment initiating a MCPTT call towards a GSM-R user equipment, wherein the call request includes the MCPTT identifier of the MCPTT user equipment; and a processor configured to access, in response to receiving the call request, a mapping of the MCPTT identifier of the MCPTT user equipment with an interworking identifier that is formed according to an address format implemented in Global System for Mobile communications, GSM, for Railways, GSM-R, wherein the processor is configured to obtain, by means of the mapping, the interworking identifier corresponding to the MCPTT identifier of the MCPTT user equipment, and to add the interworking identifier to the call request; wherein the transceiver is configured to forward the call request to an interworking function associated with the GSM-R system, characterized in that the mapping is stored in a user profile that includes a binding between the MCPTT identifier, the interworking identifier, and an identifier of the MCPTT server.
System for a compression therapy, comprising - a compression means, - a photoplethysmographic sensor, - a computer, wherein measured values of the photoplethysmographic sensor can be transmitted to the computer, and wherein the computer comprises means for performing a method for checking the compression therapy, wherein the method comprises the following steps: i. receiving measured values of the photoplethysmographic sensor during the compression therapy, ii. determining a refilling time on the basis of the received measured values of the photoplethysmographic sensor, iii. checking whether the determined refilling time undershoots a predefined lower limit, iv. optionally outputting an alarm if the check reveals that the predefined lower limit is undershot, v. checking whether the determined refilling time exceeds a predefined upper limit, vi. optionally outputting an alarm if the check reveals that the predefined upper limit is exceeded. - a compression means, - a photoplethysmographic sensor, - a computer, i. receiving measured values of the photoplethysmographic sensor during the compression therapy, ii. determining a refilling time on the basis of the received measured values of the photoplethysmographic sensor, iii. checking whether the determined refilling time undershoots a predefined lower limit, iv. optionally outputting an alarm if the check reveals that the predefined lower limit is undershot, v. checking whether the determined refilling time exceeds a predefined upper limit, vi. optionally outputting an alarm if the check reveals that the predefined upper limit is exceeded.
A radiation sterilized hydrogel comprising: a hydrocolloid in an amount of below 6 wt%, the hydrocolloid comprising gellan gum, high acyl gellan gum, low acyl gellan gum or combinations thereof; a carboxylic acid in an amount of above 0.05 wt%, wherein the carboxylic acid comprises citric acid; and water in an amount above about 94 wt%. a hydrocolloid in an amount of below 6 wt%, the hydrocolloid comprising gellan gum, high acyl gellan gum, low acyl gellan gum or combinations thereof; a carboxylic acid in an amount of above 0.05 wt%, wherein the carboxylic acid comprises citric acid; and water in an amount above about 94 wt%.
A computer-based method of evaluating a radiotherapy treatment plan for ion based radiotherapy, comprising the following steps, performed by a processor, for each of at least a first and a second portion in a treatment volume, of - Obtaining information related to the incident energy of ions that will stop in the portion, - Calculate a quantity value representative of the incident energy of the ions that will stop in the portion, characterized in that the method is - Using the quantity values calculated for the first and second portion as a measure of the robustness of the radiotherapy treatment plan. - Obtaining information related to the incident energy of ions that will stop in the portion, - Calculate a quantity value representative of the incident energy of the ions that will stop in the portion, characterized in that the method is - Using the quantity values calculated for the first and second portion as a measure of the robustness of the radiotherapy treatment plan.
A fixed wing aircraft, comprising: a primary powertrain to provide power to a propulsion unit; a secondary powertrain to provide power to the propulsion unit; and a detachable power coupling to transfer power to the secondary powertrain from a source external to the fixed wing aircraft during takeoff, the detachable power coupling is to be detachably coupled to a cable to provide electrical power to the secondary powertrain, the detachable power coupling to enable detachment of the cable following takeoff. a primary powertrain to provide power to a propulsion unit; a secondary powertrain to provide power to the propulsion unit; and a detachable power coupling to transfer power to the secondary powertrain from a source external to the fixed wing aircraft during takeoff, the detachable power coupling is to be detachably coupled to a cable to provide electrical power to the secondary powertrain, the detachable power coupling to enable detachment of the cable following takeoff.
An end effector for a surgical device, the end effector comprising: an anvil assembly; and a cartridge assembly pivotally coupled to the anvil assembly, the cartridge assembly including: a staple cartridge; a cartridge carrier including an elongated support channel configured to receive the staple cartridge, the elongated support channel defined by an inner first surface and a pair of inner second surfaces; characterised in that the inner first surface includes a recess defined therein; and a strain gauge is disposed within the recess of the cartridge carrier. an anvil assembly; and a cartridge assembly pivotally coupled to the anvil assembly, the cartridge assembly including: a staple cartridge; a cartridge carrier including an elongated support channel configured to receive the staple cartridge, the elongated support channel defined by an inner first surface and a pair of inner second surfaces; characterised in that the inner first surface includes a recess defined therein; and a strain gauge is disposed within the recess of the cartridge carrier. a staple cartridge; a cartridge carrier including an elongated support channel configured to receive the staple cartridge, the elongated support channel defined by an inner first surface and a pair of inner second surfaces; characterised in that the inner first surface includes a recess defined therein; and a strain gauge is disposed within the recess of the cartridge carrier.
An implantable medical device, comprising: a medical module; an antenna; a transceiver operatively coupled to said antenna and said medical module and facilitating wireless transmission of data between said medical module and an external device; and an impedance match circuit operatively coupled between said transceiver and said antenna; characterised by said impedance match circuit having a plurality of predetermined selectable configurations, each individual one of the plurality of configurations corresponding to different predetermined impedances. a medical module; an antenna; a transceiver operatively coupled to said antenna and said medical module and facilitating wireless transmission of data between said medical module and an external device; and an impedance match circuit operatively coupled between said transceiver and said antenna; characterised by said impedance match circuit having a plurality of predetermined selectable configurations, each individual one of the plurality of configurations corresponding to different predetermined impedances.
A confectionary image design system, comprising a display adapted to display a graphical user interface through which a user defines a pattern of confectionary pieces to be arranged on a substrate; a computer processor adapted to control the graphical user interface through which the user defines the pattern on the substrate, and to provide instructions for arranging the confectionary pieces in the defined pattern; at least one container adapted to retain the confectionary pieces used to form the defined pattern; and a robot comprising a robotic production system and a robot controller, the robot controller receiving from the computer processor the instructions for arranging the confectionary pieces; the robot controller controlling the robotic production system to retrieve the confectionary pieces stored in the at least one container and arrange the pieces on the substrate in the pattern defined by the user, wherein the user defines the pattern by selecting points on a grid displayed in the graphical user interface, with the selected points on the grid corresponding to placement of the confectionary pieces on the substrate, and wherein the substrate comprises depressions arranged in a grid corresponding to the grid displayed on the graphical user interface, and wherein the robot controller controls the robotic production system to place individual confectionary pieces in the depressions in a pattern corresponding to the selected points on the grid displayed on the graphical user interface.
A marine diesel cylinder lubricating oil composition is provided which comprises (a) a major amount of one or more Group I basestocks, and (b) a detergent composition comprising (i) 0.1 to 35 wt. % on an actives basis of one or more alkaline earth metal salts of an alkyl-substituted hydroxyaromatic carboxylic acid having a total base number of 100 to 250, based on the total weight of the marine diesel cylinder lubricating oil composition; and (ii) 0.1 to 34 wt. % on an actives basis of one or more high overbased alkyl aromatic sulfonic acids or salts thereof, based on the total weight of the marine diesel cylinder lubricating oil composition; wherein the aromatic moiety of the alkyl aromatic sulfonic acids or salts thereof contains no hydroxyl groups; and wherein the marine diesel cylinder lubricating oil composition has a TBN of 5 to 120; wherein TBN is measured in accordance with ASTM Standard No. D2896 or an equivalent procedure; wherein the one or more high overbased alkyl aromatic sulfonic acids or salts thereof have a TBN of greater than 250; and wherein the one or more alkaline earth metal salts of an alkyl-substituted hydroxyaromatic carboxylic acid are one or more alkaline earth metal salts of an alkyl-substituted hydroxybenzoic acid.
A thermal sleeve (12, 12') for protecting an electronic member (14, 14') operably connected to an elongate wiring harness (16, 16'), comprising: a tubular member (26, 26') including a circumferentially continuous wall (28, 28') with an insulative inner layer (30, 30') bounding an inner cavity (32, 32') extending along a central longitudinal axis (34; 134) between open opposite ends (36, 36', 38, 38') and a reflective outer layer (40, 40'); and a positioning member (25, 25'; 125) having an annular portion (42, 42'; 142) attached to the tubular member (26, 26') and at least one resilient finger (44, 44'; 144) having a fixed end attached to the annular portion, characterised in that said at least one finger (44, 44'; 144) extends radially inwardly along a plane from said fixed end along an arcuate path to a free (48, 48'; 148) end configured for abutment with the wiring harness (16, 16'), said at least one finger being compressible radially outwardly along said plane toward said annular portion (42, 42'; 142) to automatically adjust to an outer envelope of the wiring harness. a tubular member (26, 26') including a circumferentially continuous wall (28, 28') with an insulative inner layer (30, 30') bounding an inner cavity (32, 32') extending along a central longitudinal axis (34; 134) between open opposite ends (36, 36', 38, 38') and a reflective outer layer (40, 40'); and a positioning member (25, 25'; 125) having an annular portion (42, 42'; 142) attached to the tubular member (26, 26') and at least one resilient finger (44, 44'; 144) having a fixed end attached to the annular portion, characterised in that said at least one finger (44, 44'; 144) extends radially inwardly along a plane from said fixed end along an arcuate path to a free (48, 48'; 148) end configured for abutment with the wiring harness (16, 16'), said at least one finger being compressible radially outwardly along said plane toward said annular portion (42, 42'; 142) to automatically adjust to an outer envelope of the wiring harness.
Device for reducing soot particles in an exhaust gas, in particular in an exhaust gas of a combustion engine, comprising an outer tube and an inner tube that is arranged in a concentric manner with respect thereto, which tubes form an intermediate space through which the exhaust gas can flow, characterized in that at least one annular electrode having a plurality of electrode tips that protrude radially into the intermediate space is arranged on the inside of the outer tube, wherein terminals (6, 7) for connecting the annular electrode and the inner tube to a high voltage source are provided for generating a radial electric field in the intermediate space, so that a uniform ionization is rendered possible in the intermediate space between the outer tube and the inner tube; wherein electrons that have exited the annular electrodes move towards the inner tube; wherein at least two annular electrodes (4a, 4b) are arranged axially one behind the other at a respective electrode spacing of 10 to 30 mm.
Device for mandibular advancement, comprising a tube and a telescopic rod associated with the tube, in which the tube and the telescopic rod can be associated with the teeth of the upper and lower arches, in which the telescopic rod comprises a threaded pin which engages a female thread of a hollow element slidably positioned in said tube, and in which the said hollow element comprises a maneuvering portion external to the tube, characterized in that the device comprises a friction element stably housed inside the maneuvering portion, the friction element being arranged between the internal walls of said maneuvering portion and the thread of the pin, and the friction element having an external surface complementarily shaped with respect to the inner walls of said maneuvering portion and a threaded internal cavity which is compatible with said thread of the pin but with thread pitch and/or inclination differentiated with respect to the corresponding values of pitch and inclination of the thread of the pin or copies the thread of the pin.
A silicone rubber composition comprising: 100 parts by mass of an organopolysiloxane having at least two alkenyl groups in a molecule and free of an aryl group; 0.1 to 5 parts by mass of (B-1) an organosiloxane having in a molecule at least one silicon-bonded aryl group, at least one silicon-bonded hydrogen atom, and free of an alkenyl group, or a mixture of component (B-1) and (B-2) an organosiloxane having in a molecule at least one aryl group and at least one alkenyl group; 0.1 to 5 parts by mass of an acrylic or a methacrylic compound; an organopolysiloxane having at least two silicon-bonded hydrogen atoms in a molecule and free of an aryl group and an alkenyl group, in an amount such that the mole ratio of silicon-bonded hydrogen atoms per 1 mole of total aliphatic unsaturated bonds in this component is 0.5 to 5; and a catalytically effective amount of a hydrosilylation reaction catalyst. 100 parts by mass of an organopolysiloxane having at least two alkenyl groups in a molecule and free of an aryl group; 0.1 to 5 parts by mass of (B-1) an organosiloxane having in a molecule at least one silicon-bonded aryl group, at least one silicon-bonded hydrogen atom, and free of an alkenyl group, or a mixture of component (B-1) and (B-2) an organosiloxane having in a molecule at least one aryl group and at least one alkenyl group; 0.1 to 5 parts by mass of an acrylic or a methacrylic compound; an organopolysiloxane having at least two silicon-bonded hydrogen atoms in a molecule and free of an aryl group and an alkenyl group, in an amount such that the mole ratio of silicon-bonded hydrogen atoms per 1 mole of total aliphatic unsaturated bonds in this component is 0.5 to 5; and a catalytically effective amount of a hydrosilylation reaction catalyst.