mhurhangee/ep-ind-claims huggingface dataset:
A compound selected from: (a) biphenyl-2-ylcarbamic acid 1-[2-({3-[2-(3-{ -2-[ -2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]propyl}phenyl)acetylamino]propyl}methyl-carbamoyl)ethyl]piperidin-4-yl ester of formula: or a pharmaceutically acceptable salt thereof; (b) biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-{[ -2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}-2,5-dimethylphenylcarbamoyl)butyl]methyl-carbamoyl} ethyl)piperidin-4-yl ester of formula: or a pharmaceutically acceptable salt thereof; and (c) biphenyl-2-ylcarbamic acid 1-{2-[(4-{[2-(3-{ -2-[ -2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]propyl}phenyl)ethylcarbamoyl]methyl}phenyl)-methylcarbamoyl]ethyl}piperidin-4-yl ester of formula: or a pharmaceutically acceptable salt thereof. (a) biphenyl-2-ylcarbamic acid 1-[2-({3-[2-(3-{ -2-[ -2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]propyl}phenyl)acetylamino]propyl}methyl-carbamoyl)ethyl]piperidin-4-yl ester of formula: or a pharmaceutically acceptable salt thereof; (b) biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-{[ -2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}-2,5-dimethylphenylcarbamoyl)butyl]methyl-carbamoyl} ethyl)piperidin-4-yl ester of formula: or a pharmaceutically acceptable salt thereof; and (c) biphenyl-2-ylcarbamic acid 1-{2-[(4-{[2-(3-{ -2-[ -2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]propyl}phenyl)ethylcarbamoyl]methyl}phenyl)-methylcarbamoyl]ethyl}piperidin-4-yl ester of formula: or a pharmaceutically acceptable salt thereof.
A film of poly-4-hydroxybutyrate or copolymer thereof, wherein the film has a tensile strength greater than 53.9MPa (5.5 kgf/mm 2), a tensile modulus less than 1775 MPa (181 kgf/mm 2) and an elongation to break of 10 to 500%, and wherein the film is derived by a continuous process, followed by orientation such that the film is stretched by more than 25% of the film's original length in one or more direction.
A lighting device, including: - a support member including a thermally-conductive elongated body extending along a longitudinal direction with a plurality of pairs (141a, 141b; 142a, 142b) of heat exchange surfaces for mounting light radiation sources (161a, 161b; 162a, 162b), the surfaces in each pair (141a, 141b; 142a, 142b) being mutually opposed transversally relative to the longitudinal direction of the elongated body, with the pairs in the plurality of pairs (141a, 141b; 142a, 142b) staggered in the longitudinal direction of the elongated body, wherein the support member includes respective light radiation source mounting boards (141a, 141b; 142a, 142b) at the heat exchange surfaces, and - a plurality of pairs of electrically-powered light radiation sources (161a, 161b; 162a, 162b) arranged at the plurality of pairs (141a, 141b; 142a, 142b) of heat exchange surfaces characterised in that - the light radiation sources (161a, 161b; 162a, 162b) include thermal pads facing towards the respective mounting boards (141a, 141b; 142a, 142b), and - the mounting boards (141a, 141b; 142a, 142b) include electrically-conductive formations extending therethrough, the electrically-conductive formations being thermally coupled (1410a, 1410b) with the thermal pads and the elongated body. - a support member including a thermally-conductive elongated body extending along a longitudinal direction with a plurality of pairs (141a, 141b; 142a, 142b) of heat exchange surfaces for mounting light radiation sources (161a, 161b; 162a, 162b), the surfaces in each pair (141a, 141b; 142a, 142b) being mutually opposed transversally relative to the longitudinal direction of the elongated body, with the pairs in the plurality of pairs (141a, 141b; 142a, 142b) staggered in the longitudinal direction of the elongated body, wherein the support member includes respective light radiation source mounting boards (141a, 141b; 142a, 142b) at the heat exchange surfaces, and - a plurality of pairs of electrically-powered light radiation sources (161a, 161b; 162a, 162b) arranged at the plurality of pairs (141a, 141b; 142a, 142b) of heat exchange surfaces characterised in that - the light radiation sources (161a, 161b; 162a, 162b) include thermal pads facing towards the respective mounting boards (141a, 141b; 142a, 142b), and - the mounting boards (141a, 141b; 142a, 142b) include electrically-conductive formations extending therethrough, the electrically-conductive formations being thermally coupled (1410a, 1410b) with the thermal pads and the elongated body.
A stent-graft suture lock comprising: a substantially tubular stent structure; graft material affixed to the stent structure, thereby creating a first stent-graft, fluid carrying conduit configured for placement in a vessel; and a plurality of fixation elements for fastening the graft material to the stent structure; characterised in that a portion of the plurality of fixation elements (226, 236) are knotted stitches, made from suture material, and having a retention element comprising a protrusion formed on the ends of at least a portion of the knotted stitches, the protrusion comprising a spherical element formed from the suture material and configured to interact with at least one of a second stent-graft, fluid carrying conduit or a vessel to prevent relative movement thereof. a substantially tubular stent structure; graft material affixed to the stent structure, thereby creating a first stent-graft, fluid carrying conduit configured for placement in a vessel; and a plurality of fixation elements for fastening the graft material to the stent structure; characterised in that a portion of the plurality of fixation elements (226, 236) are knotted stitches, made from suture material, and having a retention element comprising a protrusion formed on the ends of at least a portion of the knotted stitches, the protrusion comprising a spherical element formed from the suture material and configured to interact with at least one of a second stent-graft, fluid carrying conduit or a vessel to prevent relative movement thereof.
A strut bearing comprising: a housing comprising a top piece and a bottom piece; and a plurality of low friction components each comprising a low friction layer comprising a low friction material, wherein the plurality of low friction components are bonded to the top piece or the bottom piece of the housing, characterized in that the plurality of low friction components are circumferentially offset from one another by at least one groove formed in at least one of the top piece and the bottom piece of the housing, wherein the at least one groove is a gap, slot, channel or trough into which a low friction component of the plurality of low friction components is disposed. a housing comprising a top piece and a bottom piece; and a plurality of low friction components each comprising a low friction layer comprising a low friction material, wherein the plurality of low friction components are bonded to the top piece or the bottom piece of the housing,
An arrangement for improved operability of a high temperature fuel cell device at higher fuel cell voltage values than nominal voltage values, each fuel cell in the fuel cell device comprising an anode side, a cathode side, and an electrolyte between the anode side and the cathode side, and the arrangement comprises a main power converter for loading fuels cells at least up to their rated power level, the main power converter comprising galvanic isolation, characterized by, that the arrangement comprises a non-isolating pre-regulator suitable for reducing voltage to a voltage level useable for the main power converter at least at low current levels in start-up and low current load situations when the fuel cell voltage is significantly higher than in nominal operation conditions, said pre-regulator being located between the fuel cells and the main power converter, and said pre-regulator being dimensioned to partial load current, and the arrangement comprises bypass means suitable for bypassing the pre-regulator at high current loads when the fuel cell voltage has decreased to the voltage level suitable for an input voltage of the main power converter.
A sliding bearing element, embodied as a half shell, comprising a support layer and a sliding layer, wherein at least one lubricant groove is formed in the sliding layer, which lubricant groove starts in an end face of the sliding bearing element extending in the direction of the axial direction, wherein a depth of the lubricant groove becomes smaller in the direction towards a groove outlet, such that the lubricant groove in the groove outlet runs out flat into the sliding surface of the sliding layer, characterized in that a floor surface of the lubricant groove has a surface with a surface structure, wherein the surface structure has a plurality of recesses.
One or more formulations of tagged proteins and one or more therapeutically-effective populations of anti-tag chimeric antigen receptor (AT-CAR) expressing T cells, wherein the protein is an antibody or an antigen-binding fragment thereof which binds a tumor-associated antigen and the proteins of each formulation of tagged proteins are the same or different and the AT-CARs of each population of AT-CAR-expressing T cells are the same or different and the AT-CAR comprises a tag-binding domain, a transmembrane domain, and a T cell activation domain, wherein the AT-CAR-expressing T cells bind the tag of the tagged proteins and induce cancer cell death, for use in a combination therapy for treating cancer in a subject wherein said one or more formulations of tagged proteins and said one or more populations of (AT-CAR)-expressing T cells are both administered to the subject, thereby treating cancer in the subject.
A method of separating a volatile compound from a liquid feed mixture comprising an emulsion, the emulsion comprising an organopolysiloxane polymer, the method comprising: contacting a first side of a first dense silicone hollow fibre membrane within an absorption module with the liquid feed mixture comprising the emulsion having at least one volatile compound, wherein the volatile compound is selected from a volatile linear- or cyclosiloxane; and contacting a second side of the first dense silicone hollow fibre membrane in the absorption module with a sweep medium comprising a sweep fluid, to produce a permeate mixture on the second side of the first membrane and a retentate mixture comprising the emulsion on the first side of the first membrane, wherein the permeate mixture is enriched in the volatile compound, and the retentate mixture is depleted in the volatile compound; wherein the sweep fluid is regenerated by desorbing the volatile compounds through the use of a membrane or membrane-free desorption module using a higher temperature than used during the absorption and recirculated into contact with the second side of the first dense membrane; and wherein the feed fluid exiting the absorption module is recirculated continuously to the first side of the first dense membrane until the process is stopped; wherein the sweep fluid comprises an organosilicon fluid. contacting a first side of a first dense silicone hollow fibre membrane within an absorption module with the liquid feed mixture comprising the emulsion having at least one volatile compound, wherein the volatile compound is selected from a volatile linear- or cyclosiloxane; and contacting a second side of the first dense silicone hollow fibre membrane in the absorption module with a sweep medium comprising a sweep fluid, to produce a permeate mixture on the second side of the first membrane and a retentate mixture comprising the emulsion on the first side of the first membrane, wherein the permeate mixture is enriched in the volatile compound, and the retentate mixture is depleted in the volatile compound; wherein the sweep fluid is regenerated by desorbing the volatile compounds through the use of a membrane or membrane-free desorption module using a higher temperature than used during the absorption and recirculated into contact with the second side of the first dense membrane; and wherein the feed fluid exiting the absorption module is recirculated continuously to the first side of the first dense membrane until the process is stopped; wherein the sweep fluid comprises an organosilicon fluid.
A liquid ejecting apparatus comprising: a liquid ejecting head that ejects liquid from nozzles formed in a nozzle surface; a recording unit having a first tank that stores the liquid to be supplied to the liquid ejecting head, a second tank which receives the liquid that has not been ejected by the liquid ejecting head and whose lower surface is arranged vertically lower than the nozzle surface, a circulation path that circulates the liquid among the first tank, the liquid ejecting head, and the second tank, and a pump that sends the liquid from the second tank to the first tank; a first atmosphere opening valve that switches the first tank between a sealed state and an atmosphere opening state; a second atmosphere opening valve that switches the second tank between a sealed state and an atmosphere opening state; a first pressure adjusting unit that can pressurize the first tank; and a second pressure adjusting unit that can depressurize the second tank, wherein the second tank has a first opening that communicates with the second pressure adjusting unit and a second opening that communicates with the second atmosphere opening valve, and the second opening is arranged at a position lower than the first opening in a vertical direction, and wherein a flow path resistance of the circulation path from the first tank to the liquid ejecting head is greater than a flow path resistance of the circulation path from the liquid ejecting head to the second tank. a liquid ejecting head that ejects liquid from nozzles formed in a nozzle surface; a recording unit having a first tank that stores the liquid to be supplied to the liquid ejecting head, a second tank which receives the liquid that has not been ejected by the liquid ejecting head and whose lower surface is arranged vertically lower than the nozzle surface, a circulation path that circulates the liquid among the first tank, the liquid ejecting head, and the second tank, and a pump that sends the liquid from the second tank to the first tank; a first atmosphere opening valve that switches the first tank between a sealed state and an atmosphere opening state; a second atmosphere opening valve that switches the second tank between a sealed state and an atmosphere opening state; a first pressure adjusting unit that can pressurize the first tank; and a second pressure adjusting unit that can depressurize the second tank, wherein the second tank has a first opening that communicates with the second pressure adjusting unit and a second opening that communicates with the second atmosphere opening valve, and the second opening is arranged at a position lower than the first opening in a vertical direction, and wherein a flow path resistance of the circulation path from the first tank to the liquid ejecting head is greater than a flow path resistance of the circulation path from the liquid ejecting head to the second tank.
A personal care composition comprising a dermatologically acceptable carrier, and from 3% to 40%, preferably from 3% to 37%, of at least one undecyl sulfate compound selected from the group consisting of: a) R 1 -O(CH 2 CHR 3 O) y -SO 3 M; b) CH 3 -(CH 2) z -CHR 2 -CH 2 -O(CH 2 CHR 3 O) y -SO 3 M; and c) mixtures thereof; where R 1 represents CH 3 (CH 2) 10, R 2 represents H or a hydrocarbon radical comprising 1 to 4 carbon atoms such that the sum of the carbon atoms in 2 and R 2 is 8, R 3 is H or CH 3, y is 0 to 7, the average value of y is 1 when y is not = 0, and M is a mono-valent or divalent, positively-charged cation, preferably selected from the group consisting of ammonium, sodium, potassium, magnesium, triethanolamine cation, and mixtures thereof, and further comprising from 0.5% to 10% of a co-surfactant, selected from the group consisting of: Cocomonoethanol Amide, Cocoamidopropyl Betaine, Laurylamidopropyl Betaine, Cocobetaine, lauryl betaine, lauryl amine oxide, sodium lauryl amphoacetate, alkyl glyceryl ethers, alkyl-di-glyceryl ethers, 1.,2-alkyl cyclic sulfites, 1,2-alkyl cyclic carbonates, 1,2-alkyl-epoxides, alkyl glycidylethers, and alkyl-1,3-dioxolanes, wherein the alkyl group contains 6 to 14 carbon atoms in linear or branched configuration; 1.,2- alkane diols where the total carbon content is from 6 to 14 carbon atoms linear or branched, methyl-2-hydroxy-decyl ethers, hydroxyethyl-2-dodecyl ether, hydroxyethyl-2-decyl ether, and mixtures thereof. a) R 1 -O(CH 2 CHR 3 O) y -SO 3 M; b) CH 3 -(CH 2) z -CHR 2 -CH 2 -O(CH 2 CHR 3 O) y -SO 3 M; and c) mixtures thereof;
A turbomachine including a casing, a low-pressure shaft mounted in rotation in the casing, a fan shaft mounted in rotation relative to the casing and a coupling assembly, the low-pressure shaft being configured to drive the fan shaft in rotation by means of the coupling assembly, the turbomachine being characterized in that the coupling assembly includes: - a first shaft which extends along an axis and integral with one among the low-pressure shaft and the fan shaft, the first shaft comprising at least a first portion having an outer face in which are formed a plurality of first axial grooves, - a second shaft coaxial with the first shaft and integral with one among the low-pressure shaft and the fan shaft, the second shaft comprising at least one second portion which surrounds the first portion and has an inner face in which are formed a plurality of second axial grooves, - a coupling device including a plurality of rolling elements and an annular cage, said cage being positioned between the first shaft and the second shaft, a plurality of recesses being formed in the cage, each of the rolling elements begin positioned on the one hand in a respective recess and on the other hand between one of the first axial grooves and one of the second axial grooves so as to couple in rotation the first and the second shaft (1, 2), and wherein each first and second groove (7, 12) has a first and a second substantially planar surface and extending along the axis, the first and the second surfaces being inclined relative to one another and wherein the dimensions of at least one of the rolling elements and the positioning of one of the second grooves relative to at least one of the first grooves are configured to supply a radial and tangential clearance to at least one of the rolling elements. - a first shaft which extends along an axis and integral with one among the low-pressure shaft and the fan shaft, the first shaft comprising at least a first portion having an outer face in which are formed a plurality of first axial grooves, - a second shaft coaxial with the first shaft and integral with one among the low-pressure shaft and the fan shaft, the second shaft comprising at least one second portion which surrounds the first portion and has an inner face in which are formed a plurality of second axial grooves, - a coupling device including a plurality of rolling elements and an annular cage, said cage being positioned between the first shaft and the second shaft, a plurality of recesses being formed in the cage, each of the rolling elements begin positioned on the one hand in a respective recess and on the other hand between one of the first axial grooves and one of the second axial grooves so as to couple in rotation the first and the second shaft (1, 2),
A method of controlling a capacitor commutated inverter device being connected to an AC voltage bus of an AC power system and converting between DC power and AC power, the inverter device including a number of converter valves (V1, V2, V3, V4, V5, V6) in a 6-pulse valve bridge and the method comprising the steps of: receiving measurements of the voltage (U AC) at the AC voltage bus, applying the measured AC voltage in a proportional control branch for obtaining an AC voltage dependent control factor (α MAX_UAC) that increases or decreases a maximum limitation signal (α MAX) in order to provide a constant AC voltage, determining a control factor (α MAX_γ') based on the commutation margin as a firing angle calculated for a given commutation margin reference (γ ref), and combining the AC voltage dependent control factor and commutation margin based control factor through selecting the lower of the commutation margin based control factor and the AC voltage dependent control factor as the maximum limitation signal (α MAX), and controlling the inverter device to provide a constant AC voltage on the bus based on the received measurements through providing the maximum limitation signal to a maximum output limitation terminal (max lim) of a DC current controller amplifier that determines a fire angle order based on a direct current control and being forced against the maximum limitation, and controlling the firing angle (α) of the converter valves using a fire angle order (α order) at the output of the DC current control amplifier for generating reactive power to or absorbing reactive power from the AC voltage bus. receiving measurements of the voltage (U AC) at the AC voltage bus, applying the measured AC voltage in a proportional control branch for obtaining an AC voltage dependent control factor (α MAX_UAC) that increases or decreases a maximum limitation signal (α MAX) in order to provide a constant AC voltage, determining a control factor (α MAX_γ') based on the commutation margin as a firing angle calculated for a given commutation margin reference (γ ref), and combining the AC voltage dependent control factor and commutation margin based control factor through selecting the lower of the commutation margin based control factor and the AC voltage dependent control factor as the maximum limitation signal (α MAX), and controlling the inverter device to provide a constant AC voltage on the bus based on the received measurements through providing the maximum limitation signal to a maximum output limitation terminal (max lim) of a DC current controller amplifier that determines a fire angle order based on a direct current control and being forced against the maximum limitation, and controlling the firing angle (α) of the converter valves using a fire angle order (α order) at the output of the DC current control amplifier for generating reactive power to or absorbing reactive power from the AC voltage bus.
A method of producing a salt of dinitramidic acid, comprising nitration of an initial compound with a nitrating acid mixture, the nitrating acid mixture comprising sulphuric acid and nitric acid, to form dinitramidic acid in an acid reaction mixture, characterised in that a guanylurea ion is added to the acid reaction mixture forming the salt of dinitramidic acid and that the salt of dinitramidic acid, guanylureadinitramide, is precipitated from the reaction mixture, which is acid at the time of precipitation.