A compound Formula: wherein: R 1 is selected from the group consisting of F, Cl, Br, and I; R 2 is selected from the group consisting of hydrogen, deuterium, F, Cl and Br; R 3 is selected from the group consisting of C 1-5 alkyl, C 2-5 alkenyl, C 3-5 cycloalkyl, C 5 cycloalkenyl, each of which is substituted with one or more, identical or different, substituents R 5, and C 2-5 alkynyl, which may be optionally substituted with one or more, identical or different, substituents R 5; and - R 4 is selected from the group consisting of H, C 1-5 alkyl optionally substituted with one or more, identical or different, substituents R 7, C 3-6 cycloalkyl optionally substituted with one or more, identical or different, substituents R 7, phenyl optionally substituted with one or more, identical or different, substituents R 8 and benzyl optionally substituted with one or more, identical or different, substituents R 8; R 5 is independently selected from the group consisting of F, OC 1-5 alkyl optionally substituted with one or more, identical or different, substituents R 7 and OC 3-5 cycloalkyl optionally substituted with one or more, identical or different, substituents R 7; R 6 is selected from the group consisting of hydrogen and deuterium; R 7 is independently selected from the group consisting of deuterium and F; and R 8 is independently selected from the group consisting of deuterium, methoxy, nitro, cyano, Cl, Br, I and F; R 9 is deuterium; and n is 0, 1, 2 or 3; or a pharmaceutically acceptable salt, hydrate, polymorph, tautomer, or solvate thereof. R 1 is selected from the group consisting of F, Cl, Br, and I; R 2 is selected from the group consisting of hydrogen, deuterium, F, Cl and Br; R 3 is selected from the group consisting of C 1-5 alkyl, C 2-5 alkenyl, C 3-5 cycloalkyl, C 5 cycloalkenyl, each of which is substituted with one or more, identical or different, substituents R 5, and C 2-5 alkynyl, which may be optionally substituted with one or more, identical or different, substituents R 5; and - R 4 is selected from the group consisting of H, C 1-5 alkyl optionally substituted with one or more, identical or different, substituents R 7, C 3-6 cycloalkyl optionally substituted with one or more, identical or different, substituents R 7, phenyl optionally substituted with one or more, identical or different, substituents R 8 and benzyl optionally substituted with one or more, identical or different, substituents R 8; - R 4 is selected from the group consisting of H, C 1-5 alkyl optionally substituted with one or more, identical or different, substituents R 7, C 3-6 cycloalkyl optionally substituted with one or more, identical or different, substituents R 7, phenyl optionally substituted with one or more, identical or different, substituents R 8 and benzyl optionally substituted with one or more, identical or different, substituents R 8; R 5 is independently selected from the group consisting of F, OC 1-5 alkyl optionally substituted with one or more, identical or different, substituents R 7 and OC 3-5 cycloalkyl optionally substituted with one or more, identical or different, substituents R 7; R 6 is selected from the group consisting of hydrogen and deuterium; R 7 is independently selected from the group consisting of deuterium and F; and R 8 is independently selected from the group consisting of deuterium, methoxy, nitro, cyano, Cl, Br, I and F; R 9 is deuterium; and n is 0, 1, 2 or 3; or a pharmaceutically acceptable salt, hydrate, polymorph, tautomer, or solvate thereof.