A system comprising: a vial adapter having a first end, a second end, and a wall extending therebetween, and a tapered exterior wall portion, the wall defining an exterior profile, the vial adapter having a vial seal, the vial adapter attachable to a vial; a packaging member having a proximal end, a distal end, and a sidewall extending therebetween and defining an interior, the sidewall of the packaging member defining an interior profile, the interior of the packaging member sized and adapted to receive the vial adapter therein, and the interior profile of the packaging member sized and shaped to substantially correspond to the exterior profile of the vial adapter, the sidewall of the packaging member comprising a cylindrical portion, a tapered portion, and a bottom arcuate portion; and a sealing member removably attachable to the proximal end of the packaging member, wherein with the vial adapter received within the interior of the packaging member and the sealing member attached to the packaging member, the sealing member seals the vial adapter within the packaging member, wherein the interior profile of the packaging member is sized and shaped to substantially correspond to the exterior profile of the vial adapter such that, with the vial adapter received within the interior of the packaging member, the vial adapter is secured within the packaging member by an interference fit and a taper lock, wherein the interference fit is provided between the bottom arcuate portion of the packaging member and the tapered exterior wall portion of the vial adapter, and wherein the taper lock comprises complementary locking tapers formed by the tapered portion of the packaging member and the tapered exterior wall portion of the vial adapter. a vial adapter having a first end, a second end, and a wall extending therebetween, and a tapered exterior wall portion, the wall defining an exterior profile, the vial adapter having a vial seal, the vial adapter attachable to a vial; a packaging member having a proximal end, a distal end, and a sidewall extending therebetween and defining an interior, the sidewall of the packaging member defining an interior profile, the interior of the packaging member sized and adapted to receive the vial adapter therein, and the interior profile of the packaging member sized and shaped to substantially correspond to the exterior profile of the vial adapter, the sidewall of the packaging member comprising a cylindrical portion, a tapered portion, and a bottom arcuate portion; and a sealing member removably attachable to the proximal end of the packaging member, wherein with the vial adapter received within the interior of the packaging member and the sealing member attached to the packaging member, the sealing member seals the vial adapter within the packaging member, wherein the interior profile of the packaging member is sized and shaped to substantially correspond to the exterior profile of the vial adapter such that, with the vial adapter received within the interior of the packaging member, the vial adapter is secured within the packaging member by an interference fit and a taper lock, wherein the interference fit is provided between the bottom arcuate portion of the packaging member and the tapered exterior wall portion of the vial adapter, and wherein the taper lock comprises complementary locking tapers formed by the tapered portion of the packaging member and the tapered exterior wall portion of the vial adapter.