mhurhangee/ep-ind-claims huggingface dataset:
A medical apparatus (600, 700, 800, 900, 1000) comprising: - a magnetic resonance imaging system comprising a magnet with an imaging zone for acquiring magnetic resonance data (642, 748) from a subject from within the imaging zone; - a memory for storing machine executable instructions (660, 662, 664, 760, 762, 764); - a processor for controlling the medical apparatus, wherein execution of the instructions causes the processor to: - acquire (100, 200, 300, 400, 506) B1 field map magnetic resonance data using the magnetic resonance imaging system, wherein the B1 field map magnetic resonance data comprises data or information which may be used to construct a B1 field map; - determine (202, 302, 402) a B1 field phase map and/or a B1 amplitude map using the B1 field map magnetic resonance data; - calculate a conductivity map from the B1 field phase map or from the B 1 field phase map and the B1 field amplitude map and/or a permittivity map from the B1 field amplitude map or from the B1 field phase map and the B1 field amplitude map and - determine (102, 206, 306, 408, 512) a temperature map from the conductivity map and/or the permittivity map. - a magnetic resonance imaging system comprising a magnet with an imaging zone for acquiring magnetic resonance data (642, 748) from a subject from within the imaging zone; - a memory for storing machine executable instructions (660, 662, 664, 760, 762, 764); - a processor for controlling the medical apparatus, wherein execution of the instructions causes the processor to: - acquire (100, 200, 300, 400, 506) B1 field map magnetic resonance data using the magnetic resonance imaging system, wherein the B1 field map magnetic resonance data comprises data or information which may be used to construct a B1 field map; - determine (202, 302, 402) a B1 field phase map and/or a B1 amplitude map using the B1 field map magnetic resonance data; - calculate a conductivity map from the B1 field phase map or from the B 1 field phase map and the B1 field amplitude map and/or a permittivity map from the B1 field amplitude map or from the B1 field phase map and the B1 field amplitude map and - determine (102, 206, 306, 408, 512) a temperature map from the conductivity map and/or the permittivity map.
Extension of an intermediate casing for an aircraft jet engine, intended to project towards the downstream end from an external shell of said intermediate casing, said extension comprising an annular connecting downstream end forming an annular groove open radially towards the outside, intended to receive nacelle covers, characterised in that said annular connecting downstream end is produced by means of a plurality of angular sectors (76a, 76b), in a number greater than or equal to three, and in that it also comprises a joining shell secured to said angular sectors (76a, 76b) forming said annular connecting downstream end, said shell being situated upstream of said angular sector and intended to extend a downstream end of the external shell of the intermediate casing.
A neurostimulation system, comprising: a lead having at least one electrode (72a, 72b, 72c, 72d) adapted for implantation in or near a target neural structure in the brain; a signal generator selectively coupled to one or more of the at least one electrode and configured to: a. apply a probe signal to one of the at least one electrode implanted in or near a target neural structure of the brain; and one or more processors configured to: b. detect at the at least one electrode a first response from the target neural structure evoked by the probe signal; c. determine a first time period between application of the probe signal and a first temporal feature of the first response; and d. generate a therapeutic signal comprising a plurality of pulses, at least two of the plurality of pulses separated by the first time period, the signal generator further configured to: e. apply the therapeutic signal to the at least one electrode or another electrode implanted in or near the target neural structure. a lead having at least one electrode (72a, 72b, 72c, 72d) adapted for implantation in or near a target neural structure in the brain; a signal generator selectively coupled to one or more of the at least one electrode and configured to: a. apply a probe signal to one of the at least one electrode implanted in or near a target neural structure of the brain; and a. apply a probe signal to one of the at least one electrode implanted in or near a target neural structure of the brain; and one or more processors configured to: b. detect at the at least one electrode a first response from the target neural structure evoked by the probe signal; c. determine a first time period between application of the probe signal and a first temporal feature of the first response; and d. generate a therapeutic signal comprising a plurality of pulses, at least two of the plurality of pulses separated by the first time period, b. detect at the at least one electrode a first response from the target neural structure evoked by the probe signal; c. determine a first time period between application of the probe signal and a first temporal feature of the first response; and d. generate a therapeutic signal comprising a plurality of pulses, at least two of the plurality of pulses separated by the first time period, the signal generator further configured to: e. apply the therapeutic signal to the at least one electrode or another electrode implanted in or near the target neural structure.
A compound of Formula or a pharmaceutically acceptable salt thereof; wherein R 1 is halo; R 2 is H; R 3 is SO 2 R 7 wherein R 7 is C 1-6 alkyl; R 4 is C 1-6 alkoxy; R 5 is piperidinyl optionally substituted with C 1-6 alkyl; R 6 is C 1-6 alkyl; or R 5 and R 6 together with the carbon atoms to which they are attached form a 5-6 membered heterocyclic ring comprising having 1-2 heteroatoms selected from N, O and S; for use in a method of treating an EML4-ALK + non-small cell lung cancer, and optionally resistant to crizotinib.
An apparatus for providing a safety strategy to a vehicle, the apparatus comprising: a sensor configured to sense information about an outside of the vehicle; a memory storing road information; and a control circuit configured to be electrically connected with the sensor and the memory, wherein the control circuit is configured to: generate a route which is toward a shoulder included in a road where the vehicle is traveling, when a transition demand of the vehicle is ignored, wherein the transition demand is output to hand over control authority to a driver of the vehicle; calculate an expected time taken to enter the shoulder; adjust an operational condition of an automatic lane change based on at least a portion of a speed of the vehicle, a speed of a following vehicle in a target lane of the route, or a distance between the vehicle and the following vehicle, when the expected time is longer than a specified time; and perform the automatic lane change toward the shoulder along the route, when the adjusted operational condition is satisfied. a sensor configured to sense information about an outside of the vehicle; a memory storing road information; and a control circuit configured to be electrically connected with the sensor and the memory, wherein the control circuit is configured to: generate a route which is toward a shoulder included in a road where the vehicle is traveling, when a transition demand of the vehicle is ignored, wherein the transition demand is output to hand over control authority to a driver of the vehicle; calculate an expected time taken to enter the shoulder; adjust an operational condition of an automatic lane change based on at least a portion of a speed of the vehicle, a speed of a following vehicle in a target lane of the route, or a distance between the vehicle and the following vehicle, when the expected time is longer than a specified time; and perform the automatic lane change toward the shoulder along the route, when the adjusted operational condition is satisfied. generate a route which is toward a shoulder included in a road where the vehicle is traveling, when a transition demand of the vehicle is ignored, wherein the transition demand is output to hand over control authority to a driver of the vehicle; calculate an expected time taken to enter the shoulder; adjust an operational condition of an automatic lane change based on at least a portion of a speed of the vehicle, a speed of a following vehicle in a target lane of the route, or a distance between the vehicle and the following vehicle, when the expected time is longer than a specified time; and perform the automatic lane change toward the shoulder along the route, when the adjusted operational condition is satisfied.
A kitchen apppliance with • a housing, • a container with an opening on a side located at the top during operation for receiving food for the preparation of meals, • a stirring and/or crushing device arranged in the container, • a drive arranged in the housing for rotatingly driving the stirring and/or comminuting tool, • a receptacle provided on the housing for the container, wherein a coupling is formed in the receptacle for transmitting a torque generated by the drive to the stirring and/or comminuting tool arranged in the container, • a heating device arranged in the housing for heating food placed in the vessel arranged in the container, • a lid for closing the opening of the container, the lid being mechanically movable between a locking position in which it tightly closes the opening of the container and an unlocking position in which it can be removed from the opening of the container, • and a control for the automatic operation of the kitchen apppliance, in particular the drive as well as the heating device, wherein a sensor system connected to the control system is provided for detecting the locking position and the unlocking position of the lid, and wherein an acoustic signal generator connected to the control is provided, characterised in that it is set up to emit a first acoustic signal when the lid moves from the unlocked position to the locked position, and to emit a second acoustic signal, different from the first acoustic signal, when the lid moves from the locked position to the unlocked position. • a housing, • a container with an opening on a side located at the top during operation for receiving food for the preparation of meals, • a stirring and/or crushing device arranged in the container, • a drive arranged in the housing for rotatingly driving the stirring and/or comminuting tool, • a receptacle provided on the housing for the container, wherein a coupling is formed in the receptacle for transmitting a torque generated by the drive to the stirring and/or comminuting tool arranged in the container, • a heating device arranged in the housing for heating food placed in the vessel arranged in the container, • a lid for closing the opening of the container, the lid being mechanically movable between a locking position in which it tightly closes the opening of the container and an unlocking position in which it can be removed from the opening of the container, • and a control for the automatic operation of the kitchen apppliance, in particular the drive as well as the heating device, wherein a sensor system connected to the control system is provided for detecting the locking position and the unlocking position of the lid, and wherein an acoustic signal generator connected to the control is provided, characterised in that it is set up to emit a first acoustic signal when the lid moves from the unlocked position to the locked position, and to emit a second acoustic signal, different from the first acoustic signal, when the lid moves from the locked position to the unlocked position.
A modified microorganism belonging to the genus of Corynebacterium for producing L-leucine, comprising a modified polypeptide having an isopropylmalate synthase activity, wherein glycine at position 561 from a N-terminus of a polypeptide consisting of the amino acid sequence of SEQ ID NO: 1 is substituted with aspartic acid in the modified polypeptide, and wherein the modified microorganism has a resistance to norleucine or L-leucine. wherein glycine at position 561 from a N-terminus of a polypeptide consisting of the amino acid sequence of SEQ ID NO: 1 is substituted with aspartic acid in the modified polypeptide, and wherein the modified microorganism has a resistance to norleucine or L-leucine.
A method for wireless communications, comprising: transmitting, by a base station to a user device, a message comprising a first field that includes cell access information for a first set of public land mobile networks, PLMNs, that provide access to an evolved packet core, EPC, the first field indicating whether a current cell is barred from providing network access to the user device in the EPC, the message further comprising a second field, separate from the first field, that includes a list of cell access information for a second set of PLMNs that provides access to a Fifth-Generation, 5G, core network, wherein the second field further indicates whether the current cell is barred from providing network access to the user device in the 5G core network; and providing, by the base station, communication services to the user device according to the message. transmitting, by a base station to a user device, a message comprising a first field that includes cell access information for a first set of public land mobile networks, PLMNs, that provide access to an evolved packet core, EPC, the first field indicating whether a current cell is barred from providing network access to the user device in the EPC, the message further comprising a second field, separate from the first field, that includes a list of cell access information for a second set of PLMNs that provides access to a Fifth-Generation, 5G, core network, wherein the second field further indicates whether the current cell is barred from providing network access to the user device in the 5G core network; and providing, by the base station, communication services to the user device according to the message.
A double spiro structure compound represented by the following Chemical Formula 1: wherein, in Chemical Formula 1, R 1 is represented by any one of Chemical Formula B or Chemical Formula C, wherein, in Chemical Formula B and Chemical Formula C, X 1 to X 3 are the same as or different from each other, and each independently CH or N; at least one of X 1 to X 3 is N; X 4 is O, S or NAr 5; L 2 and L 3 are the same as or different from each other, and each independently a direct bond; a substituted or unsubstituted monocyclic or multicyclic arylene group having 6 to 30 carbon atoms; or a substituted or unsubstituted heteroarylene group having 2 to 30 carbon atoms; Ar 3 to Ar 5 are the same as or different from each other, and each independently selected from the group consisting of a substituted or unsubstituted arylamine group; a substituted or unsubstituted monocyclic or multicyclic aryl group having 6 to 30 carbon atoms; and a substituted or unsubstituted heteroaryl group having 2 to 30 carbon atoms; and Cy1 is a substituted or unsubstituted monocyclic or multicyclic hydrocarbon ring having 3 to 30 carbon atoms; or a substituted or unsubstituted monocyclic or multicyclic heteroring having 2 to 30 carbon atoms, and with the proviso that the compound is none of the following: X 1 to X 3 are the same as or different from each other, and each independently CH or N; at least one of X 1 to X 3 is N; X 4 is O, S or NAr 5; L 2 and L 3 are the same as or different from each other, and each independently a direct bond; a substituted or unsubstituted monocyclic or multicyclic arylene group having 6 to 30 carbon atoms; or a substituted or unsubstituted heteroarylene group having 2 to 30 carbon atoms; Ar 3 to Ar 5 are the same as or different from each other, and each independently selected from the group consisting of a substituted or unsubstituted arylamine group; a substituted or unsubstituted monocyclic or multicyclic aryl group having 6 to 30 carbon atoms; and a substituted or unsubstituted heteroaryl group having 2 to 30 carbon atoms; and Cy1 is a substituted or unsubstituted monocyclic or multicyclic hydrocarbon ring having 3 to 30 carbon atoms; or a substituted or unsubstituted monocyclic or multicyclic heteroring having 2 to 30 carbon atoms,
An ink supply system for a printer having a scanning printhead comprising: a housing member; an ink fluid circuit within said housing member, said ink fluid circuit comprising; a recirculation tank enclosed within said housing member; a recirculation pump enclosed within said housing member, said pump configured to pulselessly draw ink from said recirculation tank and to pulselessly impel ink within said circuit; a heating assembly mounted to said housing member for heating ink impelled by said recirculation pump; a sensor assembly comprising first and second pressure sensors (105a, b) and first and second temperature sensors (107a, b) mounted to said housing member and configured to detect the pressure and temperature of: ink received from said heating assembly and; return ink received from one or more printheads; and a control system housed within said housing member and configured to be responsive to said sensors and operable to adjust said recirculation pump speed and temperature of said heating assembly, characterized in that: the housing member is mounted to the scanning printhead to travel with the printhead as it scans; and, the recirculation tank is in fluid communication with an air pump operable for maintaining acceptable pressure within said recirculation tank. a housing member; an ink fluid circuit within said housing member, said ink fluid circuit comprising; a recirculation tank enclosed within said housing member; a recirculation pump enclosed within said housing member, said pump configured to pulselessly draw ink from said recirculation tank and to pulselessly impel ink within said circuit; a heating assembly mounted to said housing member for heating ink impelled by said recirculation pump; a sensor assembly comprising first and second pressure sensors (105a, b) and first and second temperature sensors (107a, b) mounted to said housing member and configured to detect the pressure and temperature of: ink received from said heating assembly and; return ink received from one or more printheads; and ink received from said heating assembly and; return ink received from one or more printheads; and a control system housed within said housing member and configured to be responsive to said sensors and operable to adjust said recirculation pump speed and temperature of said heating assembly, characterized in that: the housing member is mounted to the scanning printhead to travel with the printhead as it scans; and, the recirculation tank is in fluid communication with an air pump operable for maintaining acceptable pressure within said recirculation tank. the housing member is mounted to the scanning printhead to travel with the printhead as it scans; and, the recirculation tank is in fluid communication with an air pump operable for maintaining acceptable pressure within said recirculation tank.
Control system for a heating, ventilation and/or air conditioning installation of a motor vehicle, said control system comprising: ▪ a first camera sensitive to wavelengths situated in the mid-infrared spectrum, and ▪ a device for processing and analyzing images capable of carrying out temperature measurements on the images of the first camera and of computing, on the basis of these measurements, at least one thermal comfort coefficient of at least one occupant of the motor vehicle, the thermal comfort coefficient being used for regulating the air temperature, the air flow rate and the air distribution within the heating, ventilation and/or air conditioning system, characterized in that the control system comprises moreover a second camera sensitive to wavelengths situated in the visible spectrum and/or in the near-infrared spectrum and in that the device for processing and analysis is capable of spotting noteworthy points (401,402,403,404,405,406) for the thermal comfort of the occupant on the images of the second camera and of transferring said noteworthy points (401,402,403,404,405,406) onto the images of the first camera, the temperature measurements of the occupant being carried out on these noteworthy points (401,402,403,404,405,406). ▪ a first camera sensitive to wavelengths situated in the mid-infrared spectrum, and ▪ a device for processing and analyzing images capable of carrying out temperature measurements on the images of the first camera and of computing, on the basis of these measurements, at least one thermal comfort coefficient of at least one occupant of the motor vehicle,
Method for producing an electrical heater which has at least one heating body with at least one contact surface and has at least one electrical resistance element which is arranged between the contact surface and a mating contact surface of a holding element which is arranged such that it can move in relation to the heating body, wherein the holding element is pressed against the resistance element with a contact-pressure force in order to hold the said resistance element on the heating body, characterized in that the contact surface and/or the mating contact surface is provided or produced with at least one breaking projection, and in that the contact-pressure force is increased, at least in regions, to such an extent that the resistance element breaks into at least two pieces (8 to 11, 31 to 34).
Safety device for preventing puncture wounds for a syringe having a syringe body and a piercing means arranged at the distal end of the syringe body, comprising a sleeve element that extends along an axial direction and encloses the piercing means and the syringe body at least in part, and a collar element that is arranged on a distal end region of the syringe body and locks the safety device in the axial direction, the collar element having at least one guide projection that is guided in at least one guide track of the sleeve element substantially along the axial direction when the syringe body is moved relative to the sleeve element, the collar element being arranged on the distal end region of the syringe body so as to be rotatable in a circumferential direction and having at least one tolerance compensation element (11a, 11b, 11c) which is mechanically in operative contact with the syringe body such that tolerances of the syringe body can be compensated, the movement of the syringe body relative to the sleeve element causing the collar element to rotate in the circumferential direction by means of the guide projection being guided in the at least one guide track of the sleeve element, characterised in that the collar element comprises a distal region in which the wall of the collar element has at least two slots (19a, 19b) that extend in the axial direction.