mhurhangee/ep-ind-claims huggingface dataset:
A hygiene nudging system for improving the overall cleanliness of a room or an area having one or more predetermined surfaces, including hand-touch-sites that is subject to frequent touching by human hands and/or fingers, said hygiene nudging system comprising - a dispenser unit being configured to dispense cleaning wipes for cleaning one or more predetermined surfaces of a room or area, - a control unit connected with the dispenser unit, wherein the system comprises a nudging unit connected with the control unit, the control unit being configured to control the nudging unit, the nudging unit is configured to issue an indication when activated by the control unit, a first sensor is connected with the dispenser unit and the control unit, the first sensor being configured to detect dispensing of cleaning wipes from the dispenser unit and to signal the detection of dispensing of cleaning wipes to the control unit, whereby the control unit deactivates the nudging unit after a predetermined time span and/or after a predetermined number of cleaning wipes having been dispensed from the dispenser unit, and wherein the dispenser unit comprises the control unit, the nudging unit and the first sensor so that the entire hygiene nudging system is comprised in one item, and wherein the system comprises a second sensor, and wherein the dispenser unit comprises the second sensor, the second sensor is configured to detect movements in the room and load of the room, wherein the control unit is configured to activate the nudging unit on the basis of data received from the second sensor. - a dispenser unit being configured to dispense cleaning wipes for cleaning one or more predetermined surfaces of a room or area, - a control unit connected with the dispenser unit, wherein the system comprises a nudging unit connected with the control unit, the control unit being configured to control the nudging unit, the nudging unit is configured to issue an indication when activated by the control unit, a first sensor is connected with the dispenser unit and the control unit, the first sensor being configured to detect dispensing of cleaning wipes from the dispenser unit and to signal the detection of dispensing of cleaning wipes to the control unit, whereby the control unit deactivates the nudging unit after a predetermined time span and/or after a predetermined number of cleaning wipes having been dispensed from the dispenser unit, and wherein the dispenser unit comprises the control unit, the nudging unit and the first sensor so that the entire hygiene nudging system is comprised in one item, and wherein the system comprises a second sensor, and wherein the dispenser unit comprises the second sensor, the second sensor is configured to detect movements in the room and load of the room, wherein the control unit is configured to activate the nudging unit on the basis of data received from the second sensor.
Method of paving a road surface, in particular renewing a road surface, comprising: spatial measurement of an existing road surface by means of a sensor; creation of a digital target milling profile; creation of a digital target height profile of a road surface to be paved and calculation of a layer thickness based on the target milling profile and the target height profile; at least partially automated control of a milling machine for milling an actual milling profile according to the specification of the target milling profile; spatial measurement of the milled actual milling profile; at least partially automated control of a road paver for paving the road surface in accordance with the specification of the target height profile. spatial measurement of an existing road surface by means of a sensor; creation of a digital target milling profile; creation of a digital target height profile of a road surface to be paved and calculation of a layer thickness based on the target milling profile and the target height profile; at least partially automated control of a milling machine for milling an actual milling profile according to the specification of the target milling profile; spatial measurement of the milled actual milling profile; at least partially automated control of a road paver for paving the road surface in accordance with the specification of the target height profile.
A viscous material feeder comprising: a nozzle to discharge a viscous material stored in a storage portion storing the viscous material; and a feeding mechanism transferring the viscous material from the storage portion to the nozzle and discharging the viscous material from the nozzle, wherein the nozzle has a bent feed route to guide the viscous material from the storage portion to a tip of the nozzle and is configured to be dividable along the bent feed route, wherein the feed route of the nozzle includes a straight passage portion formed in a linear manner and continuing from an entrance portion, and an inclined passage portion connected to the straight passage portion and inclined with respect to the straight passage portion, and wherein the inclined passage portion has a circularly cross-sectional surface and a constant flow path width, and linearly extends obliquely downward from a portion connecting to the straight passage portion toward an exit portion. a nozzle to discharge a viscous material stored in a storage portion storing the viscous material; and a feeding mechanism transferring the viscous material from the storage portion to the nozzle and discharging the viscous material from the nozzle, wherein the nozzle has a bent feed route to guide the viscous material from the storage portion to a tip of the nozzle and is configured to be dividable along the bent the feed route of the nozzle includes a straight passage portion formed in a linear manner and continuing from an entrance portion, and an inclined passage portion connected to the straight passage portion and inclined with respect to the straight passage portion, and wherein the inclined passage portion has a circularly cross-sectional surface and a constant flow path width, and linearly extends obliquely downward from a portion connecting to the straight passage portion toward an exit portion.
Wave winding device, comprising: a supply device which provides at least one winding wire via at least one winding nozzle and transports it in a supply direction, a winding device (5, 4) which winds up the supplied winding wire and comprises a mould core which is driven in rotation about an axis of rotation and extends in a transport direction, a wire entrainment device which is designed to seize one or more of the windings lying on the mould core and entrain them in the transport direction, the wire entrainment device comprises the following: a plurality of transport jaw elements which each have a plurality of wire receiving grooves, a transport jaw positioning device which is arranged in the region of the mould core and is designed to set the transport jaw elements onto the winding wire lying on the mould core, a transport jaw receiving device which is designed to receive transport jaw elements, and a transport jaw entrainment device (8.11, 8.21) which is designed to engage together with the transport jaw elements and move these in the transport direction, and characterised in that the transport jaw elements are loose. a supply device which provides at least one winding wire via at least one winding nozzle and transports it in a supply direction, a winding device (5, 4) which winds up the supplied winding wire and comprises a mould core which is driven in rotation about an axis of rotation and extends in a transport direction, a wire entrainment device which is designed to seize one or more of the windings lying on the mould core and entrain them in the transport direction, the wire entrainment device comprises the following: a plurality of transport jaw elements which each have a plurality of wire receiving grooves, a transport jaw positioning device which is arranged in the region of the mould core and is designed to set the transport jaw elements onto the winding wire lying on the mould core, a transport jaw receiving device which is designed to receive transport jaw elements, and a transport jaw entrainment device (8.11, 8.21) which is designed to engage together with the transport jaw elements and move these in the transport direction, and characterised in that the transport jaw elements are loose. a plurality of transport jaw elements which each have a plurality of wire receiving grooves, a transport jaw positioning device which is arranged in the region of the mould core and is designed to set the transport jaw elements onto the winding wire lying on the mould core, a transport jaw receiving device which is designed to receive transport jaw elements, and a transport jaw entrainment device (8.11, 8.21) which is designed to engage together with the transport jaw elements and move these in the transport direction, and characterised in that the transport jaw elements are loose.
- A device for compacting a tubular structure, including: - a support element defining a circulation passage of a cylindrical surface intended to receive the tubular structure, the circulation passage having a central axis (A-A') intended to be coaxial with the cylindrical surface, the support element and the cylindrical surface being intended to be mounted rotating relative to one another about the central axis (A-A'); - at least one compacting roller assembly, borne by the support element, the roller assembly including: * a straight central shaft, having a longitudinal axis (B-B'); * a plurality of compacting rollers, mounted parallel to one another about the central shaft, each compacting roller having a peripheral surface rotating around the central shaft about a roller axis (C-C'); wherein the longitudinal axis (B-B') of the central shaft is parallel to the central axis (A-A'), each roller axis (C-C') being inclined by a nonzero incline angle (α) relative to the longitudinal axis (B-B') of the central shaft. - a support element defining a circulation passage of a cylindrical surface intended to receive the tubular structure, the circulation passage having a central axis (A-A') intended to be coaxial with the cylindrical surface, the support element and the cylindrical surface being intended to be mounted rotating relative to one another about the central axis (A-A'); - at least one compacting roller assembly, borne by the support element, the roller assembly including: * a straight central shaft, having a longitudinal axis (B-B'); * a plurality of compacting rollers, mounted parallel to one another about the central shaft, each compacting roller having a peripheral surface rotating around the central shaft about a roller axis (C-C'); * a straight central shaft, having a longitudinal axis (B-B'); * a plurality of compacting rollers, mounted parallel to one another about the central shaft, each compacting roller having a peripheral surface rotating around the central shaft about a roller axis (C-C');
A syringe assembly, comprising: a syringe having a distal end, a proximal end, and a sidewall extending between the distal end and the proximal end, and a syringe drip guard (10, 10') is connected to the syringe and extends around at least a circumferential portion of the sidewall, characterized in that the syringe drip guard (10, 10') is connected to the syringe between the distal end and the proximal end of the syringe; wherein the syringe drip guard (10, 10') has an outer wall protruding radially outward relative to the sidewall and distally toward the distal end, wherein a channel is defined between the outer wall of the syringe drip guard (10, 10') and the sidewall of the syringe, the channel having a closed proximal end and an open distal end, and wherein the syringe drip guard (10, 10') is configured to collect fluid within the channel. a syringe having a distal end, a proximal end, and a sidewall extending between the distal end and the proximal end, and a syringe drip guard (10, 10') is connected to the syringe and extends around at least a circumferential portion of the sidewall, characterized in that the syringe drip guard (10, 10') is connected to the syringe between the distal end and the proximal end of the syringe; wherein the syringe drip guard (10, 10') has an outer wall protruding radially outward relative to the sidewall and distally toward the distal end, wherein a channel is defined between the outer wall of the syringe drip guard (10, 10') and the sidewall of the syringe, the channel having a closed proximal end and an open distal end, and wherein the syringe drip guard (10, 10') is configured to collect fluid within the channel.
A therapeutic agent that inhibits a platelet derived growth factor receptor beta (PDGFRβ) for use in a method of treating or preventing tumor metastasis, in a subject having a gain of function p53 mutation that increases its oncogenic properties relative to wild type, wherein the tumor is a pancreatic cancer tumor, a colorectal cancer tumor, or an ovarian cancer tumor.
A lithium positive electrode active material comprising at least 95 wt% spinel having a chemical composition of Li x Ni y Mn 2-y-z1-z2 D1 z1 D2 z2 O 4, wherein 09≤ x ≤ 1.1, 0.4≤y≤0.5, 0.005 ≤ z1 ≤ 0.2, 0 ≤ z2 ≤ 0.2, wherein D1 is a dopant chosen between the following elements: Co, Cu, Ti, Zn, Mg, Fe or combinations thereof, wherein D2 is a dopant chosen between Cu, Ti, Zn, Mg, Fe or combinations thereof, where D1 and D2 are different dopants, wherein the lithium positive electrode active material is a powder composed of material particles, wherein the distribution of dopant D1 is non-uniform along a radial axis of the material particles and wherein the distribution of the dopant D2 is uniform along the radial axis of the material particles.
A method for producing an aqueous dispersion containing a tetrafluoroethylene copolymer, characterized by comprising a polymerization step of subjecting tetrafluoroethylene and a (perfluoroalkyl) ethylene represented by the following formula to a polymerization reaction, in an aqueous medium, using a polymerization initiator, in the presence of a fluorinated emulsifier selected from the group consisting of C 4-7 fluorinated carboxylic acids having from 1 to 4 etheric oxygen atoms, and salts thereof, to obtain an aqueous emulsion having particles of a tetrafluoroethylene copolymer dispersed with a solid content concentration of from 10 to 45 mass%, and a concentrating step of adding a nonionic surfactant represented by the following formula to the aqueous emulsion, followed by concentration to a solid content concentration of from 50 to 70 mass% to obtain an aqueous dispersion, wherein in the polymerization step, tetrafluoroethylene is continuously or intermittently supplied to the polymerization reaction vessel, the (perfluoroalkyl) ethylene is initially added all at once, and a chain transfer agent is added at the time when from 10 to 95 mass% of the total mass of tetrafluoroethylene to be used in the polymerization reaction has been supplied, CH 2 =CH-Rf in the formula, Rf is a C 1-7 perfluoroalkyl group, R 1 -O-A-H wherein R 1 is a C 8-18 alkyl group, and A is a polyoxyalkylene chain composed of an average repeating number of from 5 to 20 oxyethylene groups and an average repeating number of from 0 to 2 oxypropylene groups.
Multi-chamber syringe with a syringe body, of which the wall encloses a hollow space, wherein the syringe body has a syringe outlet and an opening for receiving a piston displaceable in the hollow space, wherein at least one displaceable stopper is arranged in the hollow space and divides the hollow space into a first chamber, for receiving a first substance, and a second chamber, for receiving a second substance, wherein the syringe body has a channel through which the first substance can flow from the first chamber into the second chamber when the stopper is positioned in such a way that the channel connects the first chamber to the second chamber, wherein the channel is formed by a material cutout in the wall, specifically on that side of the wall facing toward the hollow space, characterized in that, starting from the syringe outlet, the internal diameter of the syringe body widens in the direction of the opening and in that, for the widening of the internal diameter, the inside wall of the syringe body extends at an opening angle with respect to the center axis, wherein the widening of the internal diameter takes place in regions, and wherein the opening angle of the first region assigned to the channel is greater than the second region assigned to the syringe outlet and the third region assigned to the opening.
Fusarium toxin-cleaving polypeptide variants of a fusarium toxin carboxylesterase of SEQ ID No. 46, characterized in that the polypeptide variants each possess an amino acid sequence truncated by 47 amino acids at the N-terminus, the amino acid sequences sharing at least 70%, preferably 80%, particularly preferably 100%, sequence identity, namely SEQ ID No. 1, with the amino acid sequence section 48-540 of SEQ ID No. 46, that the temperature stability (T(50%) of the polypeptide of SEQ ID No. 46 is determined to be 42°C and that of the polypeptide variant of SEQ ID No. 1 is determined to be 45°, or modifications of SEQ ID No. 1 comprise relative increases of T(50%) as compared to the parental enzyme of SEQ ID No. 1, wherein on at least one position selected from the group consisting of 10, 33, 66, 107, 140, 144, 149, 151, 157, 199, 266, 267, 270, 272, 275, 280, 284, 286, 293, 302, 312, 329, 332, 360, 363, 364, 365, 367, 371, 372, 377, 389, 391, 394, 418, 419, 424, 427, 429, 430, 436, 440, 443, 447, 453, 455, 456, 457, 462, 463, 464, 465, 469, 473, 478, 487 and 490 an amino acid substitution is contained as modification, and that the amino acid substituents at positions 10 and 456 are selected from Q, E, N, H, K and R, at positions 33, 107, 293 and 332 from E, Q, D, K, R and N, at positions 66, 463 and 478 from D, E, K, N, Q and R, at positions 140 and 490 from P, A, S and N, at positions 144 and 367 from I, L, M and V, at positions 149, 270, 312, 329 and 372 from F, Y, W and H, at positions 151 and 453 from D, E, K and R, at positions 157 and 462 from F, H, W and Y, at positions 199, 302, 365 and 464 from I, L, M and V, at positions 266 and 455 and from A, S and T, at positions 267, 394 and 429 from A, N, P and S, at position 272 from H, N, Q and S, at position 275 from A, D, E, G, K, N, Q, R and S, at position 280 from A, D, E, K, N, P, Q, R and S, at position 284 from A, N, P, S, T and V, at position 286 from A, D, E, K, N, P, R and S, at positions 360, 377, 391, 419 and 427 from A, I, L S, T and V, at positions 363, 443 and 457 from A, S, T and V, at position 364 from H, I, L, M, N, Q, S and V, at position 371 from A, I, L, M, S, T and V, at position 389 from I, L, M and V, at positions 418, 430, 447 and 473 from A, G and S, at position 424 from A, D, E, G, K, R and S, at position 436 from A, G, S and T, at position 440 from A, G, S and T, at position 465 from A, G, H, N, Q, S and T, at position 469 from D, E, K and R and/or at position 487 from N, D, Q, H and S.
Riding assistance system for a vehicle which is drivable by muscle power and/or additionally by motor power, such as an electric bicycle, e-bike or pedelec, which vehicle has at least one front wheel and one rear wheel and a brake system for braking at least the front wheel, having a controllable electrical generator-motor unit, - which is mountable on or in the region of a hub of the front wheel, and - which is couplable to the front wheel and/or to a rotation of the front wheel such that the rotation of the front wheel can thus be influenced by braking and/or acceleration, - which controls the generator-motor unit by means of the front wheel such that, in this way, in a generator mode, energy is coupled out of a rotation of the front wheel, acts as a brake, suppresses a rotation of the front wheel wheel, prevents and/or brakes the acceleration thereof, wherein the generator-motor unit is designed to be operable by short-circuiting, in particular in the manner of a brake chopper, and - which actuates the front wheel such that, in this way, the generator-motor unit, in a motor mode, couples energy into a rotation of the front wheel, acts as a drive and initiates, maintains and/or accelerates a rotation of the front wheel, wherein the riding assistance system is configured to, in the event of detection of a risk of an RLM scenario and if a brake pressure of the underlying brake system is not generated and/or demanded, activate the generator-motor unit in the motor mode to accelerate the front wheel such that the risk of the RLM scenario is thus alleviated or eliminated. - which is mountable on or in the region of a hub of the front wheel, and - which is couplable to the front wheel and/or to a rotation of the front wheel such that the rotation of the front wheel can thus be influenced by braking and/or acceleration, - which controls the generator-motor unit by means of the front wheel such that, in this way, in a generator mode, energy is coupled out of a rotation of the front wheel, acts as a brake, suppresses a rotation of the front wheel wheel, prevents and/or brakes the acceleration thereof, wherein the generator-motor unit is designed to be operable by short-circuiting, in particular in the manner of a brake chopper, and - which actuates the front wheel such that, in this way, the generator-motor unit, in a motor mode, couples energy into a rotation of the front wheel, acts as a drive and initiates, maintains and/or accelerates a rotation of the front wheel,
A tool holder for the internal machining, more particularly internal honing, of a workpiece using a tool comprising a geometrically undefined cutting edge, having a spindle, having a tool receptacle having a drive connection to the spindle for moving the accommodated tool, and having a unit for pressing the tool in the infeed direction against the workpiece, wherein the unit comprises a support which can engage on the inner side of the workpiece, which is guided on the toolholder (1, 22, 24) so it is settable in its distance to the tool, which tool is rotatably mounted via the tool receptacle on the toolholder (1, 22, 24), characterized in that the support and tool receptacle are arranged diametrically opposite on the shaft sides (17, 18) to relieve the toolholder (1, 22, 24) with respect to bending.
A method of skiving metal using a skiving blade, comprising: forming a nick in a surface of a metal material; introducing the skiving blade into the nick; and advancing the skiving blade from the nick into the metal material thereby forming a shaving; characterized in that: forming the nick comprises forming a recess in the metal material, wherein forming the recess comprises forming an acute ledge in the metal material directed toward a direction of advancement of the skiving blade. forming a nick in a surface of a metal material; introducing the skiving blade into the nick; and advancing the skiving blade from the nick into the metal material thereby forming a shaving; characterized in that: forming the nick comprises forming a recess in the metal material, wherein forming the recess comprises forming an acute ledge in the metal material directed toward a direction of advancement of the skiving blade. forming the nick comprises forming a recess in the metal material, wherein forming the recess comprises forming an acute ledge in the metal material directed toward a direction of advancement of the skiving blade.