A method of evaluating a physiological condition of a patient using a biological simulation model comprising: providing a set of symptomatic actions for selection obtained from an identification of subjective and objective signs from a clinical examination of the patient; receiving measurements of biological elements from a blood sample of the patient, the respective biological elements being managed by hormones produced by glands of the endocrine system of the patient, wherein the glands and respective hormones are organizable in axes including a corticotropic axis, gonadotropic axis, thyreotropic axis and somatotropic axis; calculating a plurality of indexes as functions of the measurements, reflecting physiological relationships between the biological elements and the hormones that manage the respective biological elements, at least some of the indexes reflecting physiological relationships between hormones across axes; evaluating the indexes by axis and in sequence from the corticotropic axis to the gonadotropic axis, and then to the thyreotropic axis and somatotropic axis, the indexes being evaluated to facilitate identification of one or more dysfunctions capable of participating in the genesis, installation and evolution of a pathology, thereby identifying a functional imbalance in a state of the patient, and recommending further actions for selection; receiving a selection of at least one of the symptomatic actions and/or further actions; recommending a set of therapeutics for both the symptomatic actions and further actions for a user to select; and producing a prescription including dosage, based on the user selection, wherein receiving the measurements comprises receiving the measurements to an apparatus comprising a processor and a memory storing executable instructions that in response to execution by the processor cause the apparatus to at least calculate the plurality of indexes. providing a set of symptomatic actions for selection obtained from an identification of subjective and objective signs from a clinical examination of the patient; receiving measurements of biological elements from a blood sample of the patient, the respective biological elements being managed by hormones produced by glands of the endocrine system of the patient, wherein the glands and respective hormones are organizable in axes including a corticotropic axis, gonadotropic axis, thyreotropic axis and somatotropic axis; calculating a plurality of indexes as functions of the measurements, reflecting physiological relationships between the biological elements and the hormones that manage the respective biological elements, at least some of the indexes reflecting physiological relationships between hormones across axes; evaluating the indexes by axis and in sequence from the corticotropic axis to the gonadotropic axis, and then to the thyreotropic axis and somatotropic axis, the indexes being evaluated to facilitate identification of one or more dysfunctions capable of participating in the genesis, installation and evolution of a pathology, thereby identifying a functional imbalance in a state of the patient, and recommending further actions for selection; receiving a selection of at least one of the symptomatic actions and/or further actions; recommending a set of therapeutics for both the symptomatic actions and further actions for a user to select; and producing a prescription including dosage, based on the user selection, wherein receiving the measurements comprises receiving the measurements to an apparatus comprising a processor and a memory storing executable instructions that in response to execution by the processor cause the apparatus to at least calculate the plurality of indexes.