mhurhangee/ep-ind-claims huggingface dataset:
An electrode array comprising: (a) at least two hydrogel islands, wherein at least two of the hydrogel islands have a corresponding electrode contacting said hydrogel island; (b) a flexible insulating substrate comprising an electrode region, a torsion relief region, and a connector region; and (c) conductors located on said substrate electrically connecting the electrodes to contact locations in the connector region, wherein all the electrodes are located in the electrode region; wherein the connector region and the electrode region are connected together through the torsion relief region; wherein the torsion relief region is narrower than the connector region, so as to reduce the bending stiffness; wherein the torsion relief region is connected to a long side of the electrode region, the long side of the electrode region being defined as the long side of the smallest rectangle that encloses all the electrodes; and wherein the connector region serves to connect the electrode array to an electrical connector and comprises a tip region and a stop region, wherein the tip region is arranged at an edge of the electrode array for allowing the electrical connector to slide onto, and wherein the stop region is arranged adjacent to the tip region and is wider than the tip region for physically stopping the electrical connector from sliding further onto the electrode array. (a) at least two hydrogel islands, wherein at least two of the hydrogel islands have a corresponding electrode contacting said hydrogel island; (b) a flexible insulating substrate comprising an electrode region, a torsion relief region, and a connector region; and (c) conductors located on said substrate electrically connecting the electrodes to contact locations in the connector region, wherein all the electrodes are located in the electrode region; wherein the connector region and the electrode region are connected together through the torsion relief region; wherein the torsion relief region is narrower than the connector region, so as to reduce the bending stiffness; wherein the torsion relief region is connected to a long side of the electrode region, the long side of the electrode region being defined as the long side of the smallest rectangle that encloses all the electrodes; and wherein the connector region serves to connect the electrode array to an electrical connector and comprises a tip region and a stop region, wherein the tip region is arranged at an edge of the electrode array for allowing the electrical connector to slide onto, and wherein the stop region is arranged adjacent to the tip region and is wider than the tip region for physically stopping the electrical connector from sliding further onto the electrode array.
A method for identifying a target site of a dimeric site-specific nuclease, the method comprising (a) providing a dimeric site-specific nuclease that cuts a double-stranded nucleic acid target site and creates a 5' overhang, wherein the target site comprises a [left-half site]-[spacer sequence]-[right-half site] structure, and the dimeric site-specific nuclease cuts the target site within the spacer sequence; (b) contacting the dimeric site-specific nuclease with a library of candidate nucleic acid molecules, wherein each nucleic acid molecule comprises a concatemer of a sequence comprising a candidate dimeric site-specific nuclease target site and a constant insert sequence, under conditions suitable for the dimeric site-specific nuclease to cut a candidate nucleic acid molecule comprising a target site of the dimeric site-specific nuclease; (c) filling in the 5' overhangs of a nucleic acid molecule that has been cut twice by the dimeric site-specific nuclease and comprises the constant insert sequence flanked by the left half-site and cut spacer sequence on one side, and the right half-site and cut spacer sequence on the other side, thereby creating blunt ends; and (d) identifying the nuclease target site cut by the dimeric site-specific nuclease by determining the sequence of the left-half site, the right-half-site, and the spacer sequence of the nucleic acid molecule of step (c). (a) providing a dimeric site-specific nuclease that cuts a double-stranded nucleic acid target site and creates a 5' overhang, wherein the target site comprises a [left-half site]-[spacer sequence]-[right-half site] structure, and the dimeric site-specific nuclease cuts the target site within the spacer sequence; (b) contacting the dimeric site-specific nuclease with a library of candidate nucleic acid molecules, wherein each nucleic acid molecule comprises a concatemer of a sequence comprising a candidate dimeric site-specific nuclease target site and a constant insert sequence, under conditions suitable for the dimeric site-specific nuclease to cut a candidate nucleic acid molecule comprising a target site of the dimeric site-specific nuclease; (c) filling in the 5' overhangs of a nucleic acid molecule that has been cut twice by the dimeric site-specific nuclease and comprises the constant insert sequence flanked by the left half-site and cut spacer sequence on one side, and the right half-site and cut spacer sequence on the other side, thereby creating blunt ends; and (d) identifying the nuclease target site cut by the dimeric site-specific nuclease by determining the sequence of the left-half site, the right-half-site, and the spacer sequence of the nucleic acid molecule of step (c).
Spacer for electrically insulating a prismatic battery cell from another prismatic battery cell or another component, having a first spacer frame with a lower edge and upper edge and a pre-definable height for enclosing the narrow sides of the prismatic battery cell and a partition wall for completely covering a broad side of the prismatic battery cell, said partition wall having a first and second surface, the lower edge of the spacer frame being materially connected to the first surface of the partition wall, and the partition wall being formed from an electrically insulating plastics film with a thickness of 0.2 mm to 0.8 mm, characterised in that congruent with the first spacer frame is a second spacer frame on the second surface of the plastics film, the upper edge of which is materially connected to the second surface of the plastics film, and each spacer frame together with the plastics film forms a space for the insertion of a prismatic battery cell, such that a broad side of the prismatic battery cell can be placed on the surface of the plastics film.
An exposure apparatus for transferring an image to a device, the exposure apparatus comprising: an optical assembly, a device stage (42, 742) for retaining the device, and an environmental system for controlling an environment in a gap between the optical assembly and the device, the environmental system including a surrounding member which has a first surface facing at least one of the device and the device stage, an immersion fluid system for delivering an immersion fluid within the surrounding member for filling the gap, and an inlet portion on the first surface of the surrounding member to inhibit the immersion fluid from leaking, characterised in that the exposure apparatus further comprises an apparatus frame by which the optical assembly is supported with optical mount isolators, each of which has a pneumatic cylinder for isolating vibration and an actuator for isolating vibration and controlling the position of the optical assembly; and in that the device stage includes a stage surface (280, 680, 780) arranged to be in approximately the same plane as an exposure surface of the device. an optical assembly, a device stage (42, 742) for retaining the device, and an environmental system for controlling an environment in a gap between the optical assembly and the device, the environmental system including a surrounding member which has a first surface facing at least one of the device and the device stage, an immersion fluid system for delivering an immersion fluid within the surrounding member for filling the gap, and an inlet portion on the first surface of the surrounding member to inhibit the immersion fluid from leaking, characterised in that the exposure apparatus further comprises an apparatus frame by which the optical assembly is supported with optical mount isolators, each of which has a pneumatic cylinder for isolating vibration and an actuator for isolating vibration and controlling the position of the optical assembly; and in that the device stage includes a stage surface (280, 680, 780) arranged to be in approximately the same plane as an exposure surface of the device.
A component cooling device (101, 201, 301, 401, 501) comprising: a circuit board (102, 202, 302, 402, 502), the circuit board (102, 202, 302, 402, 502) having an upper side (103, 203, 303, 403, 503) and a lower side (104, 204, 304, 404, 504) facing away from the upper side (103, 203, 303, 403, 503); and at least one electronic component (6, 106, 206, 306, 406, 506) and at least one hollow circuit board opening (107, 207, 307a, 307b, 407, 507) for a gaseous cooling medium for cooling the component, characterised in that on the lower side (104, 204, 304, 404, 504) of the circuit board (102, 202, 302, 402, 502) is provided a guide (10, 110, 210, 310, 410, 510) which forms a flow channel (109, 209, 309, 409, 509) that has at least one inlet (13, 113, 213, 313, 413, 513) and at least one outlet which is formed by the at least one circuit board opening (107, 207, 307a, 307b, 407, 507), for at least one convection flow (108, 208, 408, 508) of the cooling medium, wherein the flow channel (109, 209, 309, 409, 509) is delimited by the guide (10, 110, 210, 310, 410, 510) and a region of the lower side (104, 204, 304, 404, 504) of the circuit board (102, 202, 302, 402, 502).
Heating system with a pressure maintenance and/or degassing device and with a heating circuit distributor, wherein a connecting unit is arranged between the pressure maintenance and/or degassing device and the heating distributor to connect them fluidically, wherein a first heating medium flow path leads from the heating circuit distributor to the pressure maintenance and/or degassing device via a pressure-dependent switching valve, and a second heating medium flow path leads from the pressure maintenance and/or degassing device to the heating circuit distributor via a pump capable of being switched on and off, depending on pressure, characterised in that the connecting unit has two separate, spaced-apart conduits (11, 12) on the side of the pressure maintenance and/or degassing device for the two heating medium flow paths, each with one conduit connection (11', 12') connectable to matching opposite conduit connections of the pressure maintenance and/or degassing device, that the connection unit has a coaxial conduit on the heating-distributor side for the two heating medium flow paths, the conduit being connectable by one single connection to a matching opposite connection on the heating circuit distributor, and that the inner conduit (13.1) of the coaxial conduit projects beyond a distributor-side end of the outer conduit (13.2) of the coaxial conduit.
A catalyst coated membrane for a water electrolyser, the catalyst coated membrane comprising: an ionomer membrane having a first surface and a second surface; an anode catalyst layer on the first surface of the ionomer membrane; and a cathode catalyst layer on the second surface of the ionomer membrane, wherein the ionomer membrane comprises reinforcement material, and wherein the reinforcement material is distributed asymmetrically relative to a central plane of the ionomer membrane such that its average location is closer to the anode catalyst layer than the cathode catalyst layer. an ionomer membrane having a first surface and a second surface; an anode catalyst layer on the first surface of the ionomer membrane; and a cathode catalyst layer on the second surface of the ionomer membrane, wherein the ionomer membrane comprises reinforcement material, and wherein the reinforcement material is distributed asymmetrically relative to a central plane of the ionomer membrane such that its average location is closer to the anode catalyst layer than the cathode catalyst layer.
A system for providing information related to a shared frequency spectrum to a wireless network that lacks Internet connectivity, comprising: one or more processors; and memory comprising instructions that are executable by the one or more processors to perform operations comprising: receiving registration of the wireless network, by a vehicle when the vehicle is within a communication range of the wireless network after having been outside the communication range of the wireless network; querying, by the vehicle, a database on behalf of the wireless network when an Internet connection is available; receiving, by the vehicle, query results comprising the information related to the shared frequency spectrum; and communicating, by the vehicle, the information related to the shared frequency spectrum to the wireless network when the vehicle or a proxy of the vehicle is again within the communication range of the wireless network after again having been outside the communication range of the wireless network; wherein the vehicle comprises one of: a satellite, an unmanned aerial vehicle, UAV, and a land vehicle. one or more processors; and memory comprising instructions that are executable by the one or more processors to perform operations comprising: receiving registration of the wireless network, by a vehicle when the vehicle is within a communication range of the wireless network after having been outside the communication range of the wireless network; querying, by the vehicle, a database on behalf of the wireless network when an Internet connection is available; receiving, by the vehicle, query results comprising the information related to the shared frequency spectrum; and communicating, by the vehicle, the information related to the shared frequency spectrum to the wireless network when the vehicle or a proxy of the vehicle is again within the communication range of the wireless network after again having been outside the communication range of the wireless network; wherein the vehicle comprises one of: a satellite, an unmanned aerial vehicle, UAV, and a land vehicle. receiving registration of the wireless network, by a vehicle when the vehicle is within a communication range of the wireless network after having been outside the communication range of the wireless network; querying, by the vehicle, a database on behalf of the wireless network when an Internet connection is available; receiving, by the vehicle, query results comprising the information related to the shared frequency spectrum; and communicating, by the vehicle, the information related to the shared frequency spectrum to the wireless network when the vehicle or a proxy of the vehicle is again within the communication range of the wireless network after again having been outside the communication range of the wireless network; wherein the vehicle comprises one of: a satellite, an unmanned aerial vehicle, UAV, and a land vehicle.
An inflatable hemostasis device (100; 200), comprising: a top plate (130; 230); and a bladder (140; 240) sealably coupled to the top plate along a perimeter of the bladder, wherein the bladder (140; 240) comprises an apex when inflated and a location indicium (160; 260) comprising a first portion linearly offset from the apex and configured to be positioned over a skin puncture site, characterised in that the location indicium (160; 260) further comprises a second portion disposed adjacent the apex and configured to be positioned over an arteriotomy, and a third portion disposed between the first portion and the second portion and configured to axially align the bladder with an artery. a top plate (130; 230); and a bladder (140; 240) sealably coupled to the top plate along a perimeter of the bladder, wherein the bladder (140; 240) comprises an apex when inflated and a location indicium (160; 260) comprising a first portion linearly offset from the apex and configured to be positioned over a skin puncture site, characterised in that the location indicium (160; 260) further comprises a second portion disposed adjacent the apex and configured to be positioned over an arteriotomy, and a third portion disposed between the first portion and the second portion and configured to axially align the bladder with an artery.
Windscreen wiper device (2; 28, 30; 74; 78) for a vehicle, in particular a motor vehicle, having - an elongate upper part, which is at least partially of flexible form, - an elongate lower part, which is at least partially of flexible form, and - a plurality of connecting elements for connecting the upper part and the lower part, wherein the connecting elements are spaced apart from one another along a longitudinal extent of the windscreen wiper device (2; 28, 30; 74; 78), characterized in that the connecting elements are fastened to the lower part by means of rotary joints, and in that the windscreen wiper device (2; 28, 30; 74; 78) is constructed according to the fin ray principle, according to which the lower part of the windscreen wiper device, and advantageously also the upper part thereof, when a compressive force occurs on the lower part does not yield in the direction of the compressive force, but rather arches in the opposite direction. - an elongate upper part, which is at least partially of flexible form, - an elongate lower part, which is at least partially of flexible form, and - a plurality of connecting elements for connecting the upper part and the lower part, wherein the connecting elements are spaced apart from one another along a longitudinal extent of the windscreen wiper device (2; 28, 30; 74; 78), characterized in that the connecting elements are fastened to the lower part by means of rotary joints, and in that the windscreen wiper device (2; 28, 30; 74; 78) is constructed according to the fin ray principle, according to which the lower part of the windscreen wiper device, and advantageously also the upper part thereof, when a compressive force occurs on the lower part does not yield in the direction of the compressive force, but rather arches in the opposite direction.
A compound of formula I or a pharmaceutically acceptable salt thereof: wherein: R A is and; R B is or R A is and R B is and R 1A, R 1B, R 2A, R 2B are selected from unsubstitued or substituted alkyl, alkenyl, or alkynyl, whereby the substituents are selected from halogen, hydroxyl, carbonyl, thiocarbonyl, alkoxy, phosphoryl, phosphate, phosphonate, phosphinate, amino, amido, amidine, imine, cyano, nitro, azido, sulfhydryl, alkylthio, sulfate, sulfonate, sulfamoyl, sulfonamido, sulfonyl, heterocyclyl, aralkyl, aromatic or heteroaromatic moieties which themselves can be substituted; R 4 and R 5 are independently selected from H, halo, alkyl, alkenyl, alkynyl, amino, amide, carboxyl, ester, or nitro; or R 4 and R 5, together with the atoms that separate them, complete a cycloalkyl, aryl, or heteroaryl; R 6 and R 7 are independently selected from H, halo, alkyl, alkenyl, alkynyl, amino, amide, carboxyl, ester, or nitro; or R 6 and R 7, together with the atoms that separate them, complete a cycloalkyl, aryl, or heteroaryl. R A is and; R B is or R A is and R B is and R 1A, R 1B, R 2A, R 2B are selected from unsubstitued or substituted alkyl, alkenyl, or alkynyl, whereby the substituents are selected from halogen, hydroxyl, carbonyl, thiocarbonyl, alkoxy, phosphoryl, phosphate, phosphonate, phosphinate, amino, amido, amidine, imine, cyano, nitro, azido, sulfhydryl, alkylthio, sulfate, sulfonate, sulfamoyl, sulfonamido, sulfonyl, heterocyclyl, aralkyl, aromatic or heteroaromatic moieties which themselves can be substituted; R 4 and R 5 are independently selected from H, halo, alkyl, alkenyl, alkynyl, amino, amide, carboxyl, ester, or nitro; or R 4 and R 5, together with the atoms that separate them, complete a cycloalkyl, aryl, or heteroaryl; R 6 and R 7 are independently selected from H, halo, alkyl, alkenyl, alkynyl, amino, amide, carboxyl, ester, or nitro; or R 6 and R 7, together with the atoms that separate them, complete a cycloalkyl, aryl, or heteroaryl. R 1A, R 1B, R 2A, R 2B are selected from unsubstitued or substituted alkyl, alkenyl, or alkynyl, whereby the substituents are selected from halogen, hydroxyl, carbonyl, thiocarbonyl, alkoxy, phosphoryl, phosphate, phosphonate, phosphinate, amino, amido, amidine, imine, cyano, nitro, azido, sulfhydryl, alkylthio, sulfate, sulfonate, sulfamoyl, sulfonamido, sulfonyl, heterocyclyl, aralkyl, aromatic or heteroaromatic moieties which themselves can be substituted; R 4 and R 5 are independently selected from H, halo, alkyl, alkenyl, alkynyl, amino, amide, carboxyl, ester, or nitro; or R 4 and R 5, together with the atoms that separate them, complete a cycloalkyl, aryl, or heteroaryl; R 6 and R 7 are independently selected from H, halo, alkyl, alkenyl, alkynyl, amino, amide, carboxyl, ester, or nitro; or R 6 and R 7, together with the atoms that separate them, complete a cycloalkyl, aryl, or heteroaryl.
A method for displaying virtual objects in an augmented reality environment performed at a computing device integrated into or communicatively coupled with a head-mounted display, HMD, device comprising a display, the method comprising: displaying a virtual object within a real world physical environment; displaying one or more user interface elements for use by a user to interact with the virtual object; receiving user input that moves one or more of the virtual object and the one or more user interface elements; determining that one or more of the virtual object and the one or more user interface elements are within a predetermined distance of a physical surface; based at least on determining that one or more of the virtual object and the one or more user interface elements are within the predetermined distance of the physical surface, transitioning the one or more user interface elements independently from the virtual object for display on the physical surface while maintaining the location of the virtual object; and displaying the one or more user interface elements on the physical surface. displaying a virtual object within a real world physical environment; displaying one or more user interface elements for use by a user to interact with the virtual object; receiving user input that moves one or more of the virtual object and the one or more user interface elements; determining that one or more of the virtual object and the one or more user interface elements are within a predetermined distance of a physical surface; based at least on determining that one or more of the virtual object and the one or more user interface elements are within the predetermined distance of the physical surface, transitioning the one or more user interface elements independently from the virtual object for display on the physical surface while maintaining the location of the virtual object; and displaying the one or more user interface elements on the physical surface.