mhurhangee/ep-ind-claims huggingface dataset:
A toxin peptide capable of selectively inhibiting a Kv1.3 potassium channel protein, said peptide having or consisting essentially of 32 to 36 amino acid residues, more preferably 33, 34 or 35 amino acid residues, said peptide having four disulphide bridges, wherein said peptide comprises the following amino acid sequence: Z X 1 X 2 C 1 X 3 X 4 X 5 X 6 X 7 C 2 X 8 X 9 X 10 C 3 X 11 X 12 X 13 K 1 C 4 T 1 X 14 G 1 K 2 C 5 X 15 N 1 R 1 K 3 C 6 X 16 C 7 T 1 N 2 C 8 X 17 wherein Pos. 1 Z is pyroglutamate (<E), glutamate, aspartate, asparagine or glutamine, 2 X 1 is lysine or arginine or nothing, 3 X 2 is glutamate or aspartate or nothing, 4 C 1 is cysteine, 5 X 3 is threonine or serine, 6 X 4 is glycine or alanine, 7 X 5 is proline or serine, 8 X 6 is glutamine, asparagine, glutamate, aspartate or lysine, 9 X 7 is histidine, phenylalanine, aspartate or glutamine, 10 C 2 is cysteine, 11 X 8 is threonine, serine, alanine, leucine or isoleucine, 12 X 9 is asparagine, glutamate, glutamine or lysine, 13 X 10 is phenylalanine, proline or histidine, 14 C 3 is cysteine, 15 X 11 is lysine or arginine, 16 X 12 is lysine or aspartate wherein preferably if X 12 is lysine then X 13 is alanine or asparagine, whereas if X 2 is aspartate then X 13 is asparagine, 17 X 13 is alanine or asparagine wherein preferably if X 12 is lysine then X 13 is alanine or asparagine, whereas if X 12 is aspartate then X 13 is asparagine, 18 K 1 is lysine, 19 C 4 is cysteine, 20 T 1 is threonine, 21 X 14 is histidine, 22 G 1 is glycine, 23 K 2 is lysine, 24 C 5 is cysteine, 25 X 15 is methionine or norleucine (Nor), 26 N 1 is asparagine, 27 R 1 is arginine, 28 K 3 is lysine, 29 C 6 is cysteine, 30 X 16 is lysine, 31 C 7 is cysteine, 32 T 1 is threonine, 33 N 2 is asparagine, 34 C 8 is cysteine, 35 X 17 is lysine or arginine
A non-therapeutic, cosmetic method for treating dermatological conditions, comprising the steps of: (a) controlling an electromagnetic radiation source to generate first and second electromagnetic radiation; (b) causing a first electromagnetic radiation to be applied to a first individual exposure area of a plurality of spatially separated individual exposure areas of a target area of skin, wherein epidermal tissue and dermal tissue of the first individual exposure area are thermally damaged; and (c) causing a second electromagnetic radiation to be applied to a second individual exposure area of a plurality of spatially separated individual exposure areas of the target area of the skin, wherein epidermal tissue and dermal tissue of the second individual exposure area are thermally damaged from a surface of the skin through an entire depth of the epidermal tissue and to at least a particular depth of the dermal tissue, wherein each of the plurality of spatially separated individual exposure areas has a lateral diameter of at least approximately 1 μm and at most approximately 500 μm, wherein the plurality of spatially separated individual exposure areas covers at least five percent of the target area and at most sixty percent of the target area, wherein the energy density of the first and second electromagnetic radiations is between 1 and 32 J/cm 2, and wherein the first and second individual exposure areas are separated from one another by an unaffected area. (a) controlling an electromagnetic radiation source to generate first and second electromagnetic radiation; (b) causing a first electromagnetic radiation to be applied to a first individual exposure area of a plurality of spatially separated individual exposure areas of a target area of skin, wherein epidermal tissue and dermal tissue of the first individual exposure area are thermally damaged; and (c) causing a second electromagnetic radiation to be applied to a second individual exposure area of a plurality of spatially separated individual exposure areas of the target area of the skin, wherein epidermal tissue and dermal tissue of the second individual exposure area are thermally damaged from a surface of the skin through an entire depth of the epidermal tissue and to at least a particular depth of the dermal tissue,
An isolated humanized monoclonal antibody or fragment thereof, wherein said antibody or said fragment specifically binds human immunoglobulin heavy chain variable region protein encoded by germline gene VH1-69, wherein said antibody or said fragment comprises: (a) a heavy chain variable region comprising the amino acid sequence QVQLVQSGAEVVKPGASVKVSCKASGYTFTSYWMHWVKQAPGQGLEWIGAVSPGNSDTSYNEKFKGKATLTVDTSASTAYMELSSLRSEDTAVYYCTRSRYGNNALDYWGQGTLVTVS (SEQ ID NO: 2) and a light chain variable region comprising the amino acid sequence (b) a heavy chain variable region comprising the amino acid sequence QVQL VQSGAEVVKPGASVKVSCKASGYTFTSYWMHWVKQAPGQGLEWIGA VSPGNSDTSYNEKFKGKATLTVDKSASTAYMELSSLRSEDTAVYYCTRSRYGNNALDYWGQGTLVTVS (SEQ ID NO: 12) and a light chain variable region comprising the amino acid sequence and wherein said antibody or said fragment further comprises an Fc domain comprising a cysteine residue for interchain disulphide bond formation, or wherein said antibody or said fragment is conjugated to a cytotoxic agent. (a) a heavy chain variable region comprising the amino acid sequence QVQLVQSGAEVVKPGASVKVSCKASGYTFTSYWMHWVKQAPGQGLEWIGAVSPGNSDTSYNEKFKGKATLTVDTSASTAYMELSSLRSEDTAVYYCTRSRYGNNALDYWGQGTLVTVS (SEQ ID NO: 2) and a light chain variable region comprising the amino acid sequence (b) a heavy chain variable region comprising the amino acid sequence QVQL VQSGAEVVKPGASVKVSCKASGYTFTSYWMHWVKQAPGQGLEWIGA VSPGNSDTSYNEKFKGKATLTVDKSASTAYMELSSLRSEDTAVYYCTRSRYGNNALDYWGQGTLVTVS (SEQ ID NO: 12) and a light chain variable region comprising the amino acid sequence and wherein said antibody or said fragment further comprises an Fc domain comprising a cysteine residue for interchain disulphide bond formation, or wherein said antibody or said fragment is conjugated to a cytotoxic agent.
A battery charging assembly for charging a battery of a mobile device comprising: a charging unit having a power converter for converting an input voltage to a desired output voltage and having a receptacle in form of a recess in the bottom surface of the charging unit, the receptacle forming a socket and having at least one electrical contact for receiving the input voltage; an output assembly coupled to the charging unit for charging a battery of a mobile device; a first input assembly detachably associated with the charging unit, said input assembly comprising an adapter for removable attachment to the charging unit, a power cord, and a plug configured to mate with a style of electrical outlet such that the charging unit is positionable at a remote location from the electrical outlet, said adapter being configured to mate with the receptacle of the charging unit, said adapter further having at least one electrical contact for mating with the at least one electrical contact of the charging unit; and a latching mechanism for removably latching the adapter in the receptacle, characterised in that the latching mechanism comprises a post defined in the receptacle and two arms (70; 96) defined on the adapter which are adapted to engage the post when the adapter is positioned in the receptacle. a charging unit having a power converter for converting an input voltage to a desired output voltage and having a receptacle in form of a recess in the bottom surface of the charging unit, the receptacle forming a socket and having at least one electrical contact for receiving the input voltage; an output assembly coupled to the charging unit for charging a battery of a mobile device; a first input assembly detachably associated with the charging unit, said input assembly comprising an adapter for removable attachment to the charging unit, a power cord, and a plug configured to mate with a style of electrical outlet such that the charging unit is positionable at a remote location from the electrical outlet, said adapter being configured to mate with the receptacle of the charging unit, said adapter further having at least one electrical contact for mating with the at least one electrical contact of the charging unit; and a latching mechanism for removably latching the adapter in the receptacle, characterised in that the latching mechanism comprises a post defined in the receptacle and two arms (70; 96) defined on the adapter which are adapted to engage the post when the adapter is positioned in the receptacle.
A process of making an n-type zinc-oxide-based thin film semiconductor by depositing a thin film material on a surface area of a substrate, either an entire surface area or a selected portion thereof, wherein deposition is by an atomic layer deposition process that is carried out at or above atmospheric pressure, wherein the temperature of the substrate during deposition is under 300°C, and wherein the atomic layer deposition process comprises simultaneously directing a series of gas flows along elongated substantially parallel channels comprising, in order, at least a first reactive gaseous material containing a zinc-containing compound having a molar flow during deposition, an inert purge gas, and a second reactive gaseous material through a plurality of output openings spaced apart from the substrate, and transporting the substrate in a direction relative to the plurality of output openings, such that any point on the surface area of the substrate experiences a sequence of the first reactive gaseous material, the inert purge gas, and the second reactive gaseous material, whereby the sequence causes a thin film to be formed by atomic layer deposition on the surface area of the substrate, wherein a volatile indium-containing compound is introduced into the first reactive gaseous material or a supplemental gaseous material such that the indium-containing compound has a molar flow at a level of greater than 20 percent of the molar flow of the zinc-containing compound, wherein the series of gas flows are provided by a deposition device comprising, facing said substrate in plan view, a series of elongated output openings, substantially in parallel, positioned over the substrate, in an output face of the deposition device, spaced within 1 mm from the surface of the substrate subject to deposition and the flows of one or more of the first and second reactive gaseous materials and inert purge gas to the substrate surface for thin film deposition provides at least part of a force separating the depositing output face of said deposition device from the surface of the substrate.
A terminal wallpaper control method, wherein the method is applied to a terminal equipped with a touchscreen, and comprises: when the terminal detects a flick operation on the touchscreen and the flick operation meets a preset condition, dynamically changing, by the terminal corresponding to the flick operation, display content of a random N% zone in a wallpaper displayed on the touchscreen, which comprises randomly changing, by the terminal, at least one of the following parameters of the random N% zone: a shape or a location, and adding dynamic display content to the random N% zone; wherein display content of the wallpaper except the random N% zone remains unchanged, and wherein N is an integer greater than or equal to 1 and less than 100 and wherein N% zone refers to an area of the wallpaper occupying N% of the area of the wallpaper, wherein the flick operation meets the preset condition comprises: a direction of the flick operation meets a preset direction condition and an absolute value of displacement of the flick operation meets a preset absolute value condition; and when the terminal detects that the flick operation stops, stopping dynamically changing display content of the random N% zone in the wallpaper, and presenting a changed N% zone, that corresponds to the dynamically changed random N% zone when the flick operation stops, wherein a display content of a 1-N% zone in the wallpaper except the changed N% zone remains unchanged. when the terminal detects a flick operation on the touchscreen and the flick operation meets a preset condition, dynamically changing, by the terminal corresponding to the flick operation, display content of a random N% zone in a wallpaper displayed on the touchscreen, which comprises randomly changing, by the terminal, at least one of the following parameters of the random N% zone: a shape or a location, and adding dynamic display content to the random N% zone; wherein display content of the wallpaper except the random N% zone remains unchanged, and wherein N is an integer greater than or equal to 1 and less than 100 and wherein N% zone refers to an area of the wallpaper occupying N% of the area of the wallpaper, wherein the flick operation meets the preset condition comprises: a direction of the flick operation meets a preset direction condition and an absolute value of displacement of the flick operation meets a preset absolute value condition; and when the terminal detects that the flick operation stops, stopping dynamically changing display content of the random N% zone in the wallpaper, and presenting a changed N% zone, that corresponds to the dynamically changed random N% zone when the flick operation stops, wherein a display content of a 1-N% zone in the wallpaper except the changed N% zone remains unchanged.
A lens unit comprising: a plurality of lenses (1, 2, 3, 4, 6, 7); and a cylindrical holder configured to hold the plurality of lenses (1, 2, 3, 4, 6, 7), wherein the plurality of lenses (1, 2, 3, 4, 6, 7) include a cemented lens obtained by bonding a second lens through an adhesive layer to a first lens, the first lens is a plastic lens including a concave lens surface facing a side of the second lens, and a first flange part surrounding the concave lens surface at an outer peripheral side, the second lens is a plastic lens including a convex lens surface bonded by the adhesive layer on the concave lens surface with facing a side of the first lens, and a second flange part surrounding the convex lens surface at an outer peripheral side, when T0 denotes a center thickness in an optical axis direction of the second lens and C denotes a thickness in an optical axis direction of the second flange part, the thicknesses T0 and C satisfy a relationship of: 2.0 ≤ T 0 / C ≤ 3.2, and when n0 denotes a refractive index of the adhesive layer, n1 denotes a refractive index of the first lens, and n2 denotes a refractive index of the second lens, the refractive indexes n0, n1, and n2 satisfy the following relationship of: n 1 − n 0 > n 2 − n 0, wherein in the second lens, when T1 denotes a dimension in an optical axis direction from the apex of the convex lens surface to a surface at the side of the first lens of the second flange part, the dimension T1 and the thickness C satisfy a relationship of: T 1 / C ≤ 1.5.
A Method for detecting a status of a rotor blade for a wind turbine, the rotor blade including at least an aerodynamic device (31, 32, 33, 34, 35, 36) for influencing the airflow flowing from the leading edge to the trailing edge of the rotor blade, the aerodynamic device (31, 32, 33, 34, 35, 36) being movable between a first configuration and a second configuration, the method comprising the steps of: - measuring an output signal measured by at least one sensor (201, 202, 203, 204) installed on the wind turbine, - moving the aerodynamic device (31, 32, 33, 34, 35, 36) between the first configuration and the second configuration, - measuring a change in the output signal induced by the moving of the aerodynamic device (31, 32, 33, 34, 35, 36) between the first configuration and the second configuration, - post-processing the measured output signal for performing an analysis of the measured change in the output signal, wherein the post-processing step is performed in the frequency domain and includes: - deriving a frequency spectrum of the output signal, - calculating an upper spectrum interval of the frequency spectrum above a frequency threshold value, - comparing the upper spectrum interval with a reference frequency spectrum, - deriving a status of the rotor blade based on said step of comparing. - measuring an output signal measured by at least one sensor (201, 202, 203, 204) installed on the wind turbine, - moving the aerodynamic device (31, 32, 33, 34, 35, 36) between the first configuration and the second configuration, - measuring a change in the output signal induced by the moving of the aerodynamic device (31, 32, 33, 34, 35, 36) between the first configuration and the second configuration, - post-processing the measured output signal for performing an analysis of the measured change in the output signal, wherein the post-processing step is performed in the frequency domain and includes: - deriving a frequency spectrum of the output signal, - calculating an upper spectrum interval of the frequency spectrum above a frequency threshold value, - deriving a frequency spectrum of the output signal, - calculating an upper spectrum interval of the frequency spectrum above a frequency threshold value, - comparing the upper spectrum interval with a reference frequency spectrum, - deriving a status of the rotor blade based on said step of comparing.
A mould layer assembly comprising: a mould face component defining: a mould profile for forming a moulded article on a first side thereof; and, a temperature control surface on an opposite side to the mould profile, which temperature control surface is separated into a plurality of temperature control zones, each zone comprising a fluid chamber at least partially defined by the temperature control surface; characterised in that: the mould face component comprises a stepped, three dimensional support profile on the temperature control surface side of the mould face component; and, the mould layer assembly comprises a mould face support assembly comprising a plurality of support elements stacked on the support profile to provide a support surface for the mould layer assembly. a mould profile for forming a moulded article on a first side thereof; and, a temperature control surface on an opposite side to the mould profile, which temperature control surface is separated into a plurality of temperature control zones, each zone comprising a fluid chamber at least partially defined by the temperature control surface; characterised in that: the mould face component comprises a stepped, three dimensional support profile on the temperature control surface side of the mould face component; and, the mould layer assembly comprises a mould face support assembly comprising a plurality of support elements stacked on the support profile to provide a support surface for the mould layer assembly. the mould face component comprises a stepped, three dimensional support profile on the temperature control surface side of the mould face component; and, the mould layer assembly comprises a mould face support assembly comprising a plurality of support elements stacked on the support profile to provide a support surface for the mould layer assembly.
Device for drying and fixing foundry molds, comprising a chamber with walls, in which walls microwave means and optionally means for generating a negative pressure in the chamber are present, characterized in that - the chamber is coextensive with a mold box (10, 210) for the casting mold (20, 220), which is fabricated in the mold box (10, 210) using a mixture of particulate filler material and binder in a 3D printing process; means for microwaves are arranged in the ceiling plate and/or in the walls of the chamber, which microwave means radiate into the box space and onto the 3D-printed casting mold (20, 220); the walls of the chamber are impermeable to microwaves; the ceiling panel contactless seals the mold box (10, 210) to high-frequency microwaves through a circumferential high-frequency seal that cooperates with the side walls of the chamber (10, 210); the mold box (10, 210) with the casting mold (20, 220) and the ceiling plate with the microwave device (100, 200) are movable relative to each other. the chamber is coextensive with a mold box (10, 210) for the casting mold (20, 220), which is fabricated in the mold box (10, 210) using a mixture of particulate filler material and binder in a 3D printing process; means for microwaves are arranged in the ceiling plate and/or in the walls of the chamber, which microwave means radiate into the box space and onto the 3D-printed casting mold (20, 220); the walls of the chamber are impermeable to microwaves; the ceiling panel contactless seals the mold box (10, 210) to high-frequency microwaves through a circumferential high-frequency seal that cooperates with the side walls of the chamber (10, 210); the mold box (10, 210) with the casting mold (20, 220) and the ceiling plate with the microwave device (100, 200) are movable relative to each other.
Arrangement for making homemade beer per serving which comprises an industrial stage of an industrial arrangement performing pre-fabrication and a domestic stage for home use performing fermentation-free brewing of beer along with preparation for consumption, the arrangement of the domestic stage comprising a brewer apparatus, a liquid transfer unit, an end product container, a gas transfer unit, and at least one beer component container (5a, 5b) filled during the industrial stage, the beer component container (5a, 5b) is placed into a receiver unit, or under a filling member and is connected to the liquid transfer unit, and a gas cartridge connects to the gas transfer unit, characterized in that the end product container is a beer bottle, the brewing apparatus having a filling member for preventing the overflowing of the beer foam from the beer bottle, and the gas transfer unit connects to the filling member (4, 4a), which empties into the beer bottle or to a siphon.
A device for reducing network feedback during operation of an electric arc furnace, the device comprising - three lines, each with one electrode and one assigned phase conductor for supplying electrical energy; - in each line a sensor for measuring the presently flowing current and a sensor for measuring the presently applied voltage; - a control and regulating unit by means of which an electrical actual value (Eist1, Eist2, Eist3) and, based thereupon, a suitable phase voltage (USOLL12, USOLL23, USOLL31) is calculable for each line from the measured current (list1, list2, list3) and the presently applied line voltage, characterised in that - a semiconductor tap changer is assigned to the furnace transformer such that, by the suitable selection of three target winding taps (TSOLL1, TSOLL2, TSOLL3) of a primary side of the furnace transformer, and with a given electrical value (ESOLL1, ESOLL2, ESOLL3), a target current (IS1, IS2, IS3) is adjustable in each line. - three lines, each with one electrode and one assigned phase conductor for supplying electrical energy; - in each line a sensor for measuring the presently flowing current and a sensor for measuring the presently applied voltage; - a control and regulating unit by means of which an electrical actual value (Eist1, Eist2, Eist3) and, based thereupon, a suitable phase voltage (USOLL12, USOLL23, USOLL31) is calculable for each line from the measured current (list1, list2, list3) and the presently applied line voltage, - a semiconductor tap changer is assigned to the furnace transformer such that, by the suitable selection of three target winding taps (TSOLL1, TSOLL2, TSOLL3) of a primary side of the furnace transformer, and with a given electrical value (ESOLL1, ESOLL2, ESOLL3), a target current (IS1, IS2, IS3) is adjustable in each line.