Apparatus comprising a closed-system grinding syringe (10, 110) for liquefying and delivering a solid dosage form, the closed-system grinding syringe (10, 110) comprising: a barrel, which is shaped so as to define (a) a lateral wall shaped so as to define a cylindrical inner surface, (b) a top barrel opening, and (c) a bottom barrel wall; a fluid port disposed on the bottom barrel wall; a plunger, which comprises (a) a plunger shaft; (b) a plunger head shaped so as to define a bottom plunger wall shaped so as to define a lower surface; and (c) a plunger-head annular seal, wherein the plunger head is insertable into and moveable within the barrel such that (a) a portion of the barrel defines a closed-system syringe chamber between the bottom barrel wall and the lower surface of the bottom plunger wall, and (b) the plunger-head annular seal forms a plunger-head fluid-tight seal between an outer surface of the plunger head and the cylindrical inner surface of the barrel; a barrel cap, which is (a) configured to be attachable to the top barrel opening so as to form a barrel-cap fluid-tight seal with the top barrel opening, and (b) shaped so as to define a cap opening through the barrel cap, wherein the plunger shaft is slidably disposed through the cap opening so as to form a plunger-head fluid-tight seal between the plunger shaft and a perimeter of the cap opening; a solid-dosage-form support disc (60, 360), which (a) is disposed below the bottom plunger wall so as to define a grinding compartment between the lower surface of the bottom plunger wall and an upper surface of the solid-dosage-form support disc (60, 360), and (b) is shaped so as to define a plurality of holes (68, 368) through the solid-dosage-form support disc (60, 360); and a knob, wherein the closed-system grinding syringe (10, 110) is configured such that when (a) the solid dosage form is disposed in the grinding compartment, (b) the plunger head is inserted into the barrel, and (c) the closed-system grinding syringe (10, 110) is oriented upright, upon activation of the knob, the grinding compartment grinds the solid dosage form (60, 360) to a powder and at least 75% of the powder passes through the plurality of holes (68, 368) into a portion of the closed-system syringe chamber below the solid-dosage-form support disc (60, 360). a barrel, which is shaped so as to define (a) a lateral wall shaped so as to define a cylindrical inner surface, (b) a top barrel opening, and (c) a bottom barrel wall; a fluid port disposed on the bottom barrel wall; a plunger, which comprises (a) a plunger shaft; (b) a plunger head shaped so as to define a bottom plunger wall shaped so as to define a lower surface; and (c) a plunger-head annular seal, wherein the plunger head is insertable into and moveable within the barrel such that (a) a portion of the barrel defines a closed-system syringe chamber between the bottom barrel wall and the lower surface of the bottom plunger wall, and (b) the plunger-head annular seal forms a plunger-head fluid-tight seal between an outer surface of the plunger head and the cylindrical inner surface of the barrel; a barrel cap, which is (a) configured to be attachable to the top barrel opening so as to form a barrel-cap fluid-tight seal with the top barrel opening, and (b) shaped so as to define a cap opening through the barrel cap, wherein the plunger shaft is slidably disposed through the cap opening so as to form a plunger-head fluid-tight seal between the plunger shaft and a perimeter of the cap opening; a solid-dosage-form support disc (60, 360), which (a) is disposed below the bottom plunger wall so as to define a grinding compartment between the lower surface of the bottom plunger wall and an upper surface of the solid-dosage-form support disc (60, 360), and (b) is shaped so as to define a plurality of holes (68, 368) through the solid-dosage-form support disc (60, 360); and a knob, wherein the closed-system grinding syringe (10, 110) is configured such that when (a) the solid dosage form is disposed in the grinding compartment, (b) the plunger head is inserted into the barrel, and (c) the closed-system grinding syringe (10, 110) is oriented upright, upon activation of the knob, the grinding compartment grinds the solid dosage form (60, 360) to a powder and at least 75% of the powder passes through the plurality of holes (68, 368) into a portion of the closed-system syringe chamber below the solid-dosage-form support disc (60, 360).