mhurhangee/ep-ind-claims huggingface dataset:
Fitting to be connected to at least one pipe, in particular plastic pipe or plastic-metal composite pipe, - with a main body, - with at least one to the main body connected supporting body for insertion into a pipe end, and - with at least one to the main body connected pressing sleeve for receiving the pipe end, - wherein the pressing sleeve has a cylindrical pressing portion, characterised in that, - the pressing sleeve is made of a metal with a microhardness of less than 65 HV, in particular less than 50 HV 1, preferably in the range from 40 to 50 HV 1 as measured according to Vickers, and - the ratio of wall thickness (s) of the pressing section to the outer diameter (d) of the pressing section is less than 0.06, preferably in the range from 0.03 to 0.06. - with a main body, - with at least one to the main body connected supporting body for insertion into a pipe end, and - with at least one to the main body connected pressing sleeve for receiving the pipe end, - wherein the pressing sleeve has a cylindrical pressing portion, - the pressing sleeve is made of a metal with a microhardness of less than 65 HV, in particular less than 50 HV 1, preferably in the range from 40 to 50 HV 1 as measured according to Vickers, and - the ratio of wall thickness (s) of the pressing section to the outer diameter (d) of the pressing section is less than 0.06, preferably in the range from 0.03 to 0.06.
A polynucleotide encoding a chimeric antigen receptor, wherein: (i) the CAR comprises: (a) an extracellular antigen-binding domain that specifically recognizes B cell maturation antigen (BCMA); (b) a spacer of at least 125 amino acids in length; (c) a transmembrane domain; and (d) an intracellular signaling region; and (ii) the nucleic acid sequence encoding the spacer comprises at least one modified splice donor and/or splice acceptor site, the modified splice donor and/or acceptor site comprising one or more nucleotide modifications corresponding to a reference splice donor and/or acceptor site contained in the sequence set forth in SEQ ID NO:621; wherein: the modified splice donor site is set forth in agtctaaatacggac (SEQ ID NO:661), tcaactggtatgtgg (SEQ ID NO:662), accatctccaaggcc (SEQ ID NO:663) and/or gccccaggtttacac (SEQ ID NO:664); and/or the modified splice acceptor site is set forth in cagtttcttcctgtatagtagactcaccgtggataaatcaa (SEQ ID NO:672), gggcaacgtgttcagctgcagcgtgatgcacgaggccctgc (SEQ ID NO: 673) and/or cgccttgtcctccttgtcccgctcctcctgttgccggacct (SEQ ID NO:766). (i) the CAR comprises: (a) an extracellular antigen-binding domain that specifically recognizes B cell maturation antigen (BCMA); (b) a spacer of at least 125 amino acids in length; (c) a transmembrane domain; and (d) an intracellular signaling region; and (ii) the nucleic acid sequence encoding the spacer comprises at least one modified splice donor and/or splice acceptor site, the modified splice donor and/or acceptor site comprising one or more nucleotide modifications corresponding to a reference splice donor and/or acceptor site contained in the sequence set forth in SEQ ID NO:621; wherein: the modified splice donor site is set forth in agtctaaatacggac (SEQ ID NO:661), tcaactggtatgtgg (SEQ ID NO:662), accatctccaaggcc (SEQ ID NO:663) and/or gccccaggtttacac (SEQ ID NO:664); and/or the modified splice acceptor site is set forth in cagtttcttcctgtatagtagactcaccgtggataaatcaa (SEQ ID NO:672), gggcaacgtgttcagctgcagcgtgatgcacgaggccctgc (SEQ ID NO: 673) and/or cgccttgtcctccttgtcccgctcctcctgttgccggacct (SEQ ID NO:766). the modified splice donor site is set forth in agtctaaatacggac (SEQ ID NO:661), tcaactggtatgtgg (SEQ ID NO:662), accatctccaaggcc (SEQ ID NO:663) and/or gccccaggtttacac (SEQ ID NO:664); and/or the modified splice acceptor site is set forth in cagtttcttcctgtatagtagactcaccgtggataaatcaa (SEQ ID NO:672), gggcaacgtgttcagctgcagcgtgatgcacgaggccctgc (SEQ ID NO: 673) and/or cgccttgtcctccttgtcccgctcctcctgttgccggacct (SEQ ID NO:766).
An intraorally disintegrating tablet, in which (i) an active ingredient-containing core particle coated with a layer comprising a water insoluble polymer and/or an enteric polymer, and a disintegrant, and (ii) a granule obtained by coating a disintegrant-containing particle with a disintegrant, have been compression molded together with an organic acid. (i) an active ingredient-containing core particle coated with a layer comprising a water insoluble polymer and/or an enteric polymer, and a disintegrant, and (ii) a granule obtained by coating a disintegrant-containing particle with a disintegrant, have been compression molded together with an organic acid.
A flexible guide catheter for use in a transvascular aortic valve replacement procedure, the guide catheter defining a substantially tubular delivery lumen through which one or more other functional catheters may be introduced to the site of the aortic valve, wherein the guide catheter comprises flexible material that permits the lumen of the guide catheter to (i) collapse in cross-section to a compact form for introduction into the vasculature, and (ii) distend in cross-section to a distended form to accommodate the size of a said functional catheter introduced therethrough, wherein the distended form is large enough to provide an inner diameter of at least 6 mm, wherein in the collapsed state, the material has an annular shape with multiple S-folds, wherein in a cross-sectional view, each of the S-folds comprises a radially inner fold and a radially outer fold, wherein the radially inner and the radially outer folds each comprise a folding edge, and wherein the folding edges of the radially inner folds are oriented into a first circumferential direction and the folding edges of the radially outer folds are oriented into a second circumferential direction which is opposite to the first circumferential direction. wherein in the collapsed state, the material has an annular shape with multiple S-folds, wherein in a cross-sectional view, each of the S-folds comprises a radially inner fold and a radially outer fold, wherein the radially inner and the radially outer folds each comprise a folding edge, and wherein the folding edges of the radially inner folds are oriented into a first circumferential direction and the folding edges of the radially outer folds are oriented into a second circumferential direction which is opposite to the first circumferential direction.
A polycarbonate resin composition containing, relative to 100 parts by mass of a polycarbonate resin containing a polycarbonate resin having a structural unit represented by general formula below, 3-200 parts by mass of a (meth)acrylate copolymer containing phenyl (meth)acrylate units and methyl methacrylate units at a / mass ratio of 5-80/95-20 and having a mass average molecular weight of 5, 000-30, 000, as measured by gel permeation chromatography in chloroform solvent calculated by using polystyrene standard
Dispensing device for a preferably liquid product, with a housing, a spray head and a protective cap, wherein the protective cap covers the spray head on the outside, wherein the protective cap can be depressed together with the spray head in order to deliver product and/or pump the product, wherein the protective cap can be manually rotated between an unblocked position and a blocked position, wherein the protective cap can be depressed manually in the unblocked position together with the spray head, and wherein the protective cap is locked against manual depression in the blocked position, characterized in that the protective cap and the spray head are coupled preferably directly by means of a rotary coupling in such a way that the protective cap and the spray head can be twisted to a limited extent relative to one another, particularly so that, upon rotation of the protective cap from the blocked position into the unblocked position, the spray head is also rotated in a predetermined delivery direction when the spray head has been twisted toward the blocked position.
A work machine comprising: a lower structure; a slewing upper structure attached to the lower structure via a slewing mechanism; an attachment (4, 5), including at least a boom, and attached to the slewing upper structure; a boom cylinder configured to drive the boom; a work tool attached to the attachment (4, 5); and a controller, wherein the controller includes a weight calculating part configured to measure a weight of a transporting object to be transported by the work tool, based on a boom cylinder pressure of the boom cylinder, and a vibration control part configured to generate a command for reducing vibration of the attachment (4, 5), wherein the work tool is a lifting magnet, and wherein the vibration control part generates a command for controlling a supply voltage with respect to the lifting magnet. a lower structure; a slewing upper structure attached to the lower structure via a slewing mechanism; an attachment (4, 5), including at least a boom, and attached to the slewing upper structure; a boom cylinder configured to drive the boom; a work tool attached to the attachment (4, 5); and a controller, wherein the controller includes a weight calculating part configured to measure a weight of a transporting object to be transported by the work tool, based on a boom cylinder pressure of the boom cylinder, and a vibration control part configured to generate a command for reducing vibration of the attachment (4, 5), a weight calculating part configured to measure a weight of a transporting object to be transported by the work tool, based on a boom cylinder pressure of the boom cylinder, and a vibration control part configured to generate a command for reducing vibration of the attachment (4, 5), wherein the work tool is a lifting magnet, and wherein the vibration control part generates a command for controlling a supply voltage with respect to the lifting magnet.
A method of applying entropy coding to a symbol associated with a block for video encoding or decoding performed by a video encoder or a video decoder respectively, the method comprising: receiving input data associated with a current block in a current picture, wherein the current block is generated by applying block partitioning to an initial block using a quadtree structure or quadtree plus binary-tree structure; determining a current symbol to be encoded or decoded from the input data, wherein the current symbol is associated with the current block; determining a current context based on first information derived from one or more neighbouring blocks and second information related to a partition depth of the current block, wherein said one or more neighbouring blocks are processed prior to the current block; and applying context-based entropy encoding or decoding to the current symbol according to the current context; wherein the current symbol corresponds to a quadtree split flag; characterized in that an index ctxlnc of the current context is determined by a number of neighbouring blocks n within said one or more neighbouring blocks having a greater quadtree depth than the current block and by a quadtree depth d of the current block according to the following equation: ctxInc = d < T 0 ? 0: d > T 1 ? T 1 − T 0 + 1: d − T 0 * N + 1 + n, wherein N is a maximum number of said one or more neighbouring blocks, T0 and T1 are two pre-determined depth threshold values, and a logic operator "x ? y: z" means "if x is TRUE or not equal to 0, evaluates it to the value of y, otherwise, evaluates it to the value of z". receiving input data associated with a current block in a current picture, wherein the current block is generated by applying block partitioning to an initial block using a quadtree structure or quadtree plus binary-tree structure; determining a current symbol to be encoded or decoded from the input data, wherein the current symbol is associated with the current block; determining a current context based on first information derived from one or more neighbouring blocks and second information related to a partition depth of the current block, wherein said one or more neighbouring blocks are processed prior to the current block; and applying context-based entropy encoding or decoding to the current symbol according to the current context; wherein the current symbol corresponds to a quadtree split flag; characterized in that an index ctxlnc of the current context is determined by a number of neighbouring blocks n within said one or more neighbouring blocks having a greater quadtree depth than the current block and by a quadtree depth d of the current block according to the following equation: ctxInc = d < T 0 ? 0: d > T 1 ? T 1 − T 0 + 1: d − T 0 * N + 1 + n, wherein N is a maximum number of said one or more neighbouring blocks, T0 and T1 are two pre-determined depth threshold values, and a logic operator "x ? y: z" means "if x is TRUE or not equal to 0, evaluates it to the value of y, otherwise, evaluates it to the value of z".
A refrigerator including a cabinet in which a storage space is formed, a door opening and closing the storage space, and a transparent panel assembly mounted on the door to see through a space behind the door, wherein the transparent panel assembly comprises: a front panel (61, 66) defining at least a part of a front appearance of the door and made of a glass material and accommodating a see-through region and a screening region, the screening region being formed at peripheries of the front panel (61, 66); a rear panel (63, 65) defining at least a part of a rear appearance of the door and made of a transparent material and accommodating a see-through region and a screening region, the screening region being formed at peripheries of the rear panel (63, 65); and an intermediate member connected between the front panel (61, 66) and the rear panel (63, 65) and made of a transparent plastic member, and the intermediate member comprises: an edge portion having both ends connected to the screening region of the front panel (61, 66) and the screening region of the rear panel (63, 65); and a partition portion formed to cross an inner volume of the edge portion to partition a gap between the front panel (61, 66) and the rear panel (63, 65) to thereby form a sealed insulation layer (601, 602, 603, 604, 605), characterized in that the intermediate member being injection-molded such that the entire structure of the intermediate member is integrally molded. a front panel (61, 66) defining at least a part of a front appearance of the door and made of a glass material and accommodating a see-through region and a screening region, the screening region being formed at peripheries of the front panel (61, 66); a rear panel (63, 65) defining at least a part of a rear appearance of the door and made of a transparent material and accommodating a see-through region and a screening region, the screening region being formed at peripheries of the rear panel (63, 65); and an intermediate member connected between the front panel (61, 66) and the rear panel (63, 65) and made of a transparent plastic member, and the intermediate member comprises: an edge portion having both ends connected to the screening region of the front panel (61, 66) and the screening region of the rear panel (63, 65); and a partition portion formed to cross an inner volume of the edge portion to partition a gap between the front panel (61, 66) and the rear panel (63, 65) to thereby form a sealed insulation layer (601, 602, 603, 604, 605), characterized in that the intermediate member being injection-molded such that the entire structure of the intermediate member is integrally molded. an edge portion having both ends connected to the screening region of the front panel (61, 66) and the screening region of the rear panel (63, 65); and a partition portion formed to cross an inner volume of the edge portion to partition a gap between the front panel (61, 66) and the rear panel (63, 65) to thereby form a sealed insulation layer (601, 602, 603, 604, 605), characterized in that the intermediate member being injection-molded such that the entire structure of the intermediate member is integrally molded.
A beamforming method of an active electronically steerable receive antenna, which receive antenna comprises an antenna array containing several receive antenna elements, the method comprising: - receiving reflected radar signals at the receive antenna elements, and obtaining received signals from the receive antenna elements; - receive processing the received signals, the receive processing comprising frequency down-conversion, and analog-to-digital conversion, thereby generating several digital signals; - aligning the received signals or the digital signals for a predetermined angle of incidence; characterized in - determining a beamformed signal, comprising multiplying several signals including a sum beamforming signal, which is determined by summing at least two of the digital signals, and a product beamforming signal, which is determined by multiplying at least two of the digital signals, wherein the product beamforming signal is a grating lobe suppression signal, which suppresses grating lobes of the sum beamforming signal when multiplied with the sum beamforming signal, wherein the aligning is performed before the determining of the beamformed signal. - receiving reflected radar signals at the receive antenna elements, and obtaining received signals from the receive antenna elements; - receive processing the received signals, the receive processing comprising frequency down-conversion, and analog-to-digital conversion, thereby generating several digital signals; - aligning the received signals or the digital signals for a predetermined angle of incidence; characterized in - aligning the received signals or the digital signals for a predetermined angle of incidence; characterized in - determining a beamformed signal, comprising multiplying several signals including a sum beamforming signal, which is determined by summing at least two of the digital signals, and a product beamforming signal, which is determined by multiplying at least two of the digital signals, wherein the product beamforming signal is a grating lobe suppression signal, which suppresses grating lobes of the sum beamforming signal when multiplied with the sum beamforming signal,
A cooling arrangement of a vehicle, comprising: - a coolant circuit for carrying a coolant flow. - a first heat transfer system which is connected into the coolant circuit and integrated into a combustion engine for cooling the combustion engine of the vehicle, - a second heat transfer system which is connected into the coolant circuit for cooling an exhaust gas turbocharger of the vehicle, and - a third heat transfer system which is connected into the coolant circuit for cooling an exhaust gas recirculation of the vehicle, characterised in that a first partial flow of the coolant flow can be applied to the first heat transfer system, wherein irrespective thereof a second and third partial flow (51, 53) of the coolant flow can be applied to the second and third heat transfer systems (41, 45), wherein the first heat transfer system is connected into a first partial circuit of the coolant circuit, the second and third heat transfer systems (41, 45) are connected into a second partial circuit of the coolant circuit and the exhaust gas recirculation and the exhaust gas turbocharger can be cooled in the case of a coolant standstill in the first heat transfer system. - a coolant circuit for carrying a coolant flow. - a first heat transfer system which is connected into the coolant circuit and integrated into a combustion engine for cooling the combustion engine of the vehicle, - a second heat transfer system which is connected into the coolant circuit for cooling an exhaust gas turbocharger of the vehicle, and - a third heat transfer system which is connected into the coolant circuit for cooling an exhaust gas recirculation of the vehicle,
An implant device for tissue and/or bone distraction, with an elongate stretching unit, which can be controlled to perform a stretching movement between two anchoring portions (14, 42) for tissue and/or bone, wherein the stretching movement is effected by length-adjustable actuating means (16, 18, 20) in the stretching unit, wherein the actuating means have a hydraulic actuating unit connected via a pressure line to a hydraulic control unit, which is provided outside the stretching unit and can be provided inside the body adjacent to the stretching unit, in order to interact therewith in such a way that, as a reaction to the hydraulic control unit applying a pressure to a hydraulic fluid guided in the pressure line, the hydraulic actuating unit effects the stretching movement of the stretching unit, wherein an electric, electromagnetic and/or thermal energy supply of the drive means in an implanted state of the implant device takes place by means of wireless energy transmission means, and wherein detector means are provided, which on the transmitter side enable a wireless and/or contactless detection of an activation and/or deactivation state of the energy supply for the drive means, and wherein the stretching unit has a detent device, which determines a gradual stretching movement in accordance with a respective detent- and/or tooth interval of the detent device, characterized in that the hydraulic control unit has drive means realized for the application of pressure by means of a shape memory alloy of a thermal and/or magnetic shape memory alloy material, wherein a structural space surrounding the shape memory alloy element has, in an inserted manner, a return spring.
A compound for use in reducing the rate of progression of dry age related macular degeneration, the compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein: each of R 1 and R 2 is independently H or a C 1 -C 6 alkyl and R 3 is H or a C 1 -C 6 alkyl, wherein the compound is to be intravitreally administered in an effective amount to a subject in need thereof. each of R 1 and R 2 is independently H or a C 1 -C 6 alkyl and R 3 is H or a C 1 -C 6 alkyl, wherein
A method for processing a used mattress, the method comprising: a compression stage for compressing the mattress into a compressed state; maintaining the mattress in the compressed state to facilitate transportation or deconstruction of the mattress; and a deconstruction stage wherein the mattress is deconstructed using high pressure water jets while in the compressed state. a compression stage for compressing the mattress into a compressed state; maintaining the mattress in the compressed state to facilitate transportation or deconstruction of the mattress; and a deconstruction stage wherein the mattress is deconstructed using high pressure water jets while in the compressed state.
A method for generating a constraint based routing comprising: when computing a routing with a constraint condition, directly computing paths from a head node to a tail node of the routing; once a path is computed, comparing the computed path with a constraint condition; if the constraint condition is satisfied, the path is added to the result set until an upper limit of a capacity of the result set is reached. when computing a routing with a constraint condition, directly computing paths from a head node to a tail node of the routing; once a path is computed, comparing the computed path with a constraint condition; if the constraint condition is satisfied, the path is added to the result set until an upper limit of a capacity of the result set is reached.