A kit for qualitative and quantitative analysis of a subject biomolecule by inductively coupled plasma mass spectrometry (ICP-MS), comprising: a first microparticle comprising: a core including a metallic material which is selected from the group consisting of lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, titanium, lead, cadmium, iron oxide (Fe 3 O 4), silicon oxide (SiO 2), and titanium oxide (TiO 2); a silica coating layer formed on the core; and a first binding means, linked to the silica coating layer, for binding specifically to a biomolecule to be analyzed, and a second microparticle comprising: a core including a magnetic material; a silica coating layer formed on the core; and a second binding means, linked to the silica coating layer, for non-specifically binding to the biomolecule to be analyzed, wherein the second binding means is a functional group that forms a chemical bond with the analysis subject biomolecule, the functional group including at least one selected from among an aldehyde group, an ether group, an ester group, a ketone group, a sulfide groups, a thiol group, an aryl group, an amine group, a carboxyl group, and a hydroxy group, and a third microparticle including a third binding means that specifically binds to the first binding means of the first microparticle and comprises a fluorescent substance or a luminescent substance, wherein the metallic material is an aggregate of single metal atoms ranging in number from 10 4 to 10 6 atoms. a core including a metallic material which is selected from the group consisting of lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, titanium, lead, cadmium, iron oxide (Fe 3 O 4), silicon oxide (SiO 2), and titanium oxide (TiO 2); a silica coating layer formed on the core; and a first binding means, linked to the silica coating layer, for binding specifically to a biomolecule to be analyzed, and a second microparticle comprising: a core including a magnetic material; a silica coating layer formed on the core; and a second binding means, linked to the silica coating layer, for non-specifically binding to the biomolecule to be analyzed, wherein the second binding means is a functional group that forms a chemical bond with the analysis subject biomolecule, the functional group including at least one selected from among an aldehyde group, an ether group, an ester group, a ketone group, a sulfide groups, a thiol group, an aryl group, an amine group, a carboxyl group, and a hydroxy group, and a core including a magnetic material; a silica coating layer formed on the core; and a second binding means, linked to the silica coating layer, for non-specifically binding to the biomolecule to be analyzed, wherein the second binding means is a functional group that forms a chemical bond with the analysis subject biomolecule, the functional group including at least one selected from among an aldehyde group, an ether group, an ester group, a ketone group, a sulfide groups, a thiol group, an aryl group, an amine group, a carboxyl group, and a hydroxy group, and a third microparticle including a third binding means that specifically binds to the first binding means of the first microparticle and comprises a fluorescent substance or a luminescent substance, wherein the metallic material is an aggregate of single metal atoms ranging in number from 10 4 to 10 6 atoms.