A work machine control system that is configured to control an actuator (8, 12) of a work machine having a boom, the work machine control system comprising: a signal processing unit (35, 36) that is configured to generate a signal related to a target operating amount of the actuator (8, 12) from an input signal; and a feedback control unit that is configured to control the actuator (8, 12) based on a difference between the signal related to the target operating amount and a signal related to a fed-back operating amount of the actuator (8, 12); characterized in that the work machine control system further comprises: a feed-forward control unit that is configured to control the actuator (8, 12) based on the signal related to the target operating amount in cooperation with the feedback control unit, and is configured to learn characteristics of the actuator (8, 12) by adjusting a weighting factor based on a teacher signal; and a calculation unit that is configured to calculate information related to a deflection of the work machine, wherein the signal processing unit (35, 36) is configured to correct intermediate information, which is generated in a process of generating the signal related to the target operating amount, based on the information related to the deflection obtained from the calculation unit, and is configured to generate the signal related to the target operating amount. a signal processing unit (35, 36) that is configured to generate a signal related to a target operating amount of the actuator (8, 12) from an input signal; and a feedback control unit that is configured to control the actuator (8, 12) based on a difference between the signal related to the target operating amount and a signal related to a fed-back operating amount of the actuator (8, 12); characterized in that the work machine control system further comprises: a feed-forward control unit that is configured to control the actuator (8, 12) based on the signal related to the target operating amount in cooperation with the feedback control unit, and is configured to learn characteristics of the actuator (8, 12) by adjusting a weighting factor based on a teacher signal; and a calculation unit that is configured to calculate information related to a deflection of the work machine, wherein the signal processing unit (35, 36) is configured to correct intermediate information, which is generated in a process of generating the signal related to the target operating amount, based on the information related to the deflection obtained from the calculation unit, and is configured to generate the signal related to the target operating amount. a feed-forward control unit that is configured to control the actuator (8, 12) based on the signal related to the target operating amount in cooperation with the feedback control unit, and is configured to learn characteristics of the actuator (8, 12) by adjusting a weighting factor based on a teacher signal; and a calculation unit that is configured to calculate information related to a deflection of the work machine, wherein the signal processing unit (35, 36) is configured to correct intermediate information, which is generated in a process of generating the signal related to the target operating amount, based on the information related to the deflection obtained from the calculation unit, and is configured to generate the signal related to the target operating amount.