A system, comprising: a flow-sensing intravascular device, comprising: a flexible elongate member having a proximal portion, a distal portion, and a central longitudinal axis, the flexible elongate member sized and shaped for insertion into a lumen of a human vasculature; and a flow sensing element fixedly secured to a distal tip of the flexible elongate member such that the flow sensing element is positioned at a distal tip of the flow-sensing intravascular device, wherein the flow sensing element is mounted at an oblique angle with respect to the central longitudinal axis of the flexible elongate member; a rotational monitor configured to monitor a rotational position of the intravascular device about the central longitudinal axis; and a processing unit in communication with the flow-sensing intravascular device and the rotational monitor, the processing unit configured to: obtain flow measurements from the flow-sensing intravascular device; output a visual representation of the obtained flow measurements to a display; and monitor relative changes in flow measurements associated with different rotational positions of the device and determine, based on the monitored relative changes, an optimal rotational position of the device for obtaining flow measurements. a flow-sensing intravascular device, comprising: a flexible elongate member having a proximal portion, a distal portion, and a central longitudinal axis, the flexible elongate member sized and shaped for insertion into a lumen of a human vasculature; and a flow sensing element fixedly secured to a distal tip of the flexible elongate member such that the flow sensing element is positioned at a distal tip of the flow-sensing intravascular device, wherein the flow sensing element is mounted at an oblique angle with respect to the central longitudinal axis of the flexible elongate member; a flexible elongate member having a proximal portion, a distal portion, and a central longitudinal axis, the flexible elongate member sized and shaped for insertion into a lumen of a human vasculature; and a flow sensing element fixedly secured to a distal tip of the flexible elongate member such that the flow sensing element is positioned at a distal tip of the flow-sensing intravascular device, wherein the flow sensing element is mounted at an oblique angle with respect to the central longitudinal axis of the flexible elongate member; a rotational monitor configured to monitor a rotational position of the intravascular device about the central longitudinal axis; and a processing unit in communication with the flow-sensing intravascular device and the rotational monitor, the processing unit configured to: obtain flow measurements from the flow-sensing intravascular device; output a visual representation of the obtained flow measurements to a display; and monitor relative changes in flow measurements associated with different rotational positions of the device and determine, based on the monitored relative changes, an optimal rotational position of the device for obtaining flow measurements. obtain flow measurements from the flow-sensing intravascular device; output a visual representation of the obtained flow measurements to a display; and monitor relative changes in flow measurements associated with different rotational positions of the device and determine, based on the monitored relative changes, an optimal rotational position of the device for obtaining flow measurements.