An endoscopy system apparatus comprising: (a) an endoscope including a control body having a docking block on the proximal end of the control body, the endoscope including at least one surgical instrument lumen, wherein one or more inlets of the at least one surgical instrument lumen are disposed at a proximal end of the docking block; (b) a docking station including a docking mechanism, (i) wherein the docking mechanism is mechanically connected to the exterior of the docking block; (ii) wherein the docking block and the docking mechanism include one matching orientation feature configured to allow the docking block to be inserted in a pre-defined single correct orientation, wherein the one matching orientation feature is configured to align the one or more inlets of surgical instrument lumen to corresponding one or more surgical instrument motorboxes when the endoscope is docked to the docking mechanism of the docking station by the docking block; and (iii) wherein the docking block and the docking mechanism together further comprise a one-touch retaining mechanism including at least one or more lock pin recesses on the docking block and one or more corresponding lock pins on the docking station configured to mechanically lock the docking block to the docking mechanisn. (a) an endoscope including a control body having a docking block on the proximal end of the control body, the endoscope including at least one surgical instrument lumen, wherein one or more inlets of the at least one surgical instrument lumen are disposed at a proximal end of the docking block; (b) a docking station including a docking mechanism, (i) wherein the docking mechanism is mechanically connected to the exterior of the docking block; (ii) wherein the docking block and the docking mechanism include one matching orientation feature configured to allow the docking block to be inserted in a pre-defined single correct orientation, wherein the one matching orientation feature is configured to align the one or more inlets of surgical instrument lumen to corresponding one or more surgical instrument motorboxes when the endoscope is docked to the docking mechanism of the docking station by the docking block; and (iii) wherein the docking block and the docking mechanism together further comprise a one-touch retaining mechanism including at least one or more lock pin recesses on the docking block and one or more corresponding lock pins on the docking station configured to mechanically lock the docking block to the docking mechanisn. (i) wherein the docking mechanism is mechanically connected to the exterior of the docking block; (ii) wherein the docking block and the docking mechanism include one matching orientation feature configured to allow the docking block to be inserted in a pre-defined single correct orientation, wherein the one matching orientation feature is configured to align the one or more inlets of surgical instrument lumen to corresponding one or more surgical instrument motorboxes when the endoscope is docked to the docking mechanism of the docking station by the docking block; and (iii) wherein the docking block and the docking mechanism together further comprise a one-touch retaining mechanism including at least one or more lock pin recesses on the docking block and one or more corresponding lock pins on the docking station configured to mechanically lock the docking block to the docking mechanisn.