A connector for use with an analytical instrument system, comprising: A) a reinforcement insert (200, 400, 500, 600, 700, 800, 900) comprising, a) a first end (201, 401, 501, 601) comprising an interior threaded portion (213, 413, 513) for connection to a system conduit; b) a second end (202, 402, 502, 602) comprising an interior threaded portion (223, 423, 523) for connection to a system conduit, c) a central portion (250, 450, 550, 650) connecting the first end to the second end, wherein the central portion is lacking interior threads; d) an interior surface that defines a fluid conduit providing a fluid connection from the first end to the second end, e) an exterior surface (257, 457, 557), wherein the central portion forms a plurality of channels (259, 459, 559, 659), each channel providing a fluid conduit from the exterior surface to the interior surface; and f) a first lip (216, 416, 516) formed in the interior surface at the junction of the threaded and non-threaded portions of the first end and a second lip (226, 426, 526) formed in the interior surface at the junction of the threaded and non-threaded portions of the second end, and B) a biocompatible molding (260, 460, 760, 860, 960), wherein the molding covers the interior surface between the first lip and the second lip and extends to the exterior surface through the fluid channels formed in the central portion. A) a reinforcement insert (200, 400, 500, 600, 700, 800, 900) comprising, a) a first end (201, 401, 501, 601) comprising an interior threaded portion (213, 413, 513) for connection to a system conduit; b) a second end (202, 402, 502, 602) comprising an interior threaded portion (223, 423, 523) for connection to a system conduit, c) a central portion (250, 450, 550, 650) connecting the first end to the second end, wherein the central portion is lacking interior threads; d) an interior surface that defines a fluid conduit providing a fluid connection from the first end to the second end, e) an exterior surface (257, 457, 557), wherein the central portion forms a plurality of channels (259, 459, 559, 659), each channel providing a fluid conduit from the exterior surface to the interior surface; and f) a first lip (216, 416, 516) formed in the interior surface at the junction of the threaded and non-threaded portions of the first end and a second lip (226, 426, 526) formed in the interior surface at the junction of the threaded and non-threaded portions of the second end, and a) a first end (201, 401, 501, 601) comprising an interior threaded portion (213, 413, 513) for connection to a system conduit; b) a second end (202, 402, 502, 602) comprising an interior threaded portion (223, 423, 523) for connection to a system conduit, c) a central portion (250, 450, 550, 650) connecting the first end to the second end, wherein the central portion is lacking interior threads; d) an interior surface that defines a fluid conduit providing a fluid connection from the first end to the second end, e) an exterior surface (257, 457, 557), wherein the central portion forms a plurality of channels (259, 459, 559, 659), each channel providing a fluid conduit from the exterior surface to the interior surface; and f) a first lip (216, 416, 516) formed in the interior surface at the junction of the threaded and non-threaded portions of the first end and a second lip (226, 426, 526) formed in the interior surface at the junction of the threaded and non-threaded portions of the second end, and B) a biocompatible molding (260, 460, 760, 860, 960), wherein the molding covers the interior surface between the first lip and the second lip and extends to the exterior surface through the fluid channels formed in the central portion.