A compound of Formula: or a pharmaceutically acceptable salt thereof, wherein R 2 is selected from F, Cl, Br, NO 2, CN, NR a R a, - r -aryl substituted with 0-3 R 2a -O-C 1-4 alkyl, -O- r -aryl substituted with 0-3 R 2a, and heterocyclyl substituted with 0-3 R 2a; R 2a, at each occurrence, is independently selected from C 1-4 alkyl, C 1-4 haloalkyl, F, Cl, Br, NO 2, CN, -OH, -SH, -OR b, -S 2 R b, -C R d, -NR a R a, -C NR a R a, -C NR a OR b, -NHC R d, -NHC NR a R a, -NHC OR b, -OC NR a R a, -C OR d, -S 2 NR a R a, -NHS 2 R b, -C NHS 2 R b, -C NR a (CH 2) r C OR d, C 3-6 cycloalkyl substituted with 0-3 R e, phenyl substituted with 0-3 R e and/or heterocyclyl substituted with 0-3 Re; Q is phenyl; R 4a is selected from F, Cl, Br, OH, and C 1-6 alkyl; R a, at each occurrence, is independently selected from H, NH 2, C 1-4 alkyl substituted with 0-3 R e, CF 3, -O-C 1-6 alkyl, -(CH 2) r OH, C 3-6 cycloalkyl substituted with 0-3 R e, phenyl substituted with 0-3 R e, and/or heterocyclyl substituted with 0-3 R e, or R a and R a together with the nitrogen atom to which they are both attached form a heterocyclyl substituted with 0-3 R e; R b, at each occurrence, is independently selected from C 1-4 alkyl, CF 3, phenyl substituted with 0-3 R e, and/or heterocyclyl substituted with 0-3 R e; R c is phenyl substituted with 0-3 Rg; R d, at each occurrence, is independently selected from H, C 1-4 alkyl, CF 3, phenyl substituted with 0-3 R e, and/or heterocyclyl substituted with 0-3 R e; R e, at each occurrence, is independently selected from C 1-4 alkyl, C 3-6 cycloalkyl, F, Cl, Br, CN, NO 2, CO 2 H, -(CH 2) r OC 1-5 alkyl, OH, SH, -(CH 2) r SC 1-5 alkyl, -(CH 2) r phenyl and/or -(CH 2) r heterocyclyl; Rg, at each occurrence, is independently selected from F, Cl, Br, OH, C 1-6 alkyl, and/or -OC 1-5 alkyl; and R, at each occurrence, is independently selected from H, C 1-6 alkyl, C 1-6 haloalkyl, and/or -(CH 2) r -aryl; n, at each occurrence, is independently selected from 0, 1, and/or 2; and r, at each occurrence, is independently selected from 0 and/or 1. R 2 is selected from F, Cl, Br, NO 2, CN, NR a R a, - r -aryl substituted with 0-3 R 2a -O-C 1-4 alkyl, -O- r -aryl substituted with 0-3 R 2a, and heterocyclyl substituted with 0-3 R 2a; R 2a, at each occurrence, is independently selected from C 1-4 alkyl, C 1-4 haloalkyl, F, Cl, Br, NO 2, CN, -OH, -SH, -OR b, -S 2 R b, -C R d, -NR a R a, -C NR a R a, -C NR a OR b, -NHC R d, -NHC NR a R a, -NHC OR b, -OC NR a R a, -C OR d, -S 2 NR a R a, -NHS 2 R b, -C NHS 2 R b, -C NR a (CH 2) r C OR d, C 3-6 cycloalkyl substituted with 0-3 R e, phenyl substituted with 0-3 R e and/or heterocyclyl substituted with 0-3 Re; Q is phenyl; R 4a is selected from F, Cl, Br, OH, and C 1-6 alkyl; R a, at each occurrence, is independently selected from H, NH 2, C 1-4 alkyl substituted with 0-3 R e, CF 3, -O-C 1-6 alkyl, -(CH 2) r OH, C 3-6 cycloalkyl substituted with 0-3 R e, phenyl substituted with 0-3 R e, and/or heterocyclyl substituted with 0-3 R e, or R a and R a together with the nitrogen atom to which they are both attached form a heterocyclyl substituted with 0-3 R e; R b, at each occurrence, is independently selected from C 1-4 alkyl, CF 3, phenyl substituted with 0-3 R e, and/or heterocyclyl substituted with 0-3 R e; R c is phenyl substituted with 0-3 Rg; R d, at each occurrence, is independently selected from H, C 1-4 alkyl, CF 3, phenyl substituted with 0-3 R e, and/or heterocyclyl substituted with 0-3 R e; R e, at each occurrence, is independently selected from C 1-4 alkyl, C 3-6 cycloalkyl, F, Cl, Br, CN, NO 2, CO 2 H, -(CH 2) r OC 1-5 alkyl, OH, SH, -(CH 2) r SC 1-5 alkyl, -(CH 2) r phenyl and/or -(CH 2) r heterocyclyl; Rg, at each occurrence, is independently selected from F, Cl, Br, OH, C 1-6 alkyl, and/or -OC 1-5 alkyl; and R, at each occurrence, is independently selected from H, C 1-6 alkyl, C 1-6 haloalkyl, and/or -(CH 2) r -aryl; n, at each occurrence, is independently selected from 0, 1, and/or 2; and r, at each occurrence, is independently selected from 0 and/or 1.