Charge air cooling unit for a two-staged turbocharger of an internal combustion engine, comprising: - a first charge air cooler having a first end face provided with a first cooling fluid inlet and a first cooling fluid outlet, - a second charge air cooler having a second end face provided with a second cooling fluid inlet and a second cooling fluid outlet, wherein the second charge air cooler is arranged adjacent to the first charge air cooler such that the first end face and the second end face are oriented in the same direction, and - a manifold unit, characterized in that the manifold unit comprises -- a first manifold connected to the first end face and configured to guide cooling fluid supplied by a first cooling fluid supply line into the first cooling fluid inlet and to guide cooling fluid discharged from the first cooling fluid outlet toward a first cooling fluid discharge line, and -- a second manifold connected to the second end face and configured to guide cooling fluid supplied by the first cooling fluid supply line to the second cooling fluid inlet and to guide cooling fluid discharged from the second cooling fluid outlet toward the first cooling fluid discharge line, wherein the first manifold is further configured to guide cooling fluid supplied by the first cooling fluid supply line toward the second charge air cooler via the second manifold and to guide cooling fluid discharged from the second charge air cooler via the second manifold toward the first cooling fluid discharge line, and wherein the second manifold is provided with a first supply channel configured to guide cooling fluid supplied into the second manifold from the first cooling fluid supply line to the second cooling fluid inlet and a second supply channel configured to guide cooling fluid supplied into the second manifold from the second cooling fluid outlet toward the first cooling fluid discharge line. - a first charge air cooler having a first end face provided with a first cooling fluid inlet and a first cooling fluid outlet, - a second charge air cooler having a second end face provided with a second cooling fluid inlet and a second cooling fluid outlet, wherein the second charge air cooler is arranged adjacent to the first charge air cooler such that the first end face and the second end face are oriented in the same direction, and - a manifold unit, the manifold unit comprises -- a first manifold connected to the first end face and configured to guide cooling fluid supplied by a first cooling fluid supply line into the first cooling fluid inlet and to guide cooling fluid discharged from the first cooling fluid outlet toward a first cooling fluid discharge line, and -- a second manifold connected to the second end face and configured to guide cooling fluid supplied by the first cooling fluid supply line to the second cooling fluid inlet and to guide cooling fluid discharged from the second cooling fluid outlet toward the first cooling fluid discharge line, wherein -- a first manifold connected to the first end face and configured to guide cooling fluid supplied by a first cooling fluid supply line into the first cooling fluid inlet and to guide cooling fluid discharged from the first cooling fluid outlet toward a first cooling fluid discharge line, and -- a second manifold connected to the second end face and configured to guide cooling fluid supplied by the first cooling fluid supply line to the second cooling fluid inlet and to guide cooling fluid discharged from the second cooling fluid outlet toward the first cooling fluid discharge line, wherein the first manifold is further configured to guide cooling fluid supplied by the first cooling fluid supply line toward the second charge air cooler via the second manifold and to guide cooling fluid discharged from the second charge air cooler via the second manifold toward the first cooling fluid discharge line, and wherein the second manifold is provided with a first supply channel configured to guide cooling fluid supplied into the second manifold from the first cooling fluid supply line to the second cooling fluid inlet and a second supply channel configured to guide cooling fluid supplied into the second manifold from the second cooling fluid outlet toward the first cooling fluid discharge line.