A cartridge for secondary batteries, the cartridge comprising: a main frame comprising at least four unit frames (101,102) connected to each other at ends thereof to provide a cavity inside the four unit frames (101, 102), wherein at least some of the unit frames (101, 102) have openings penetrating therethrough in a horizontal direction and the main frame being configured to be vertically stackable on at least another main frame; an upper cooling plate having a plate shape, comprising an upper bonding portion serving as edges and bonded to the main frame, and arranged to cover the cavity; and a lower cooling plate having a plate shape, comprising a lower bonding portion serving as edges and bonded to the main frame, and spaced apart from the upper cooling plate by a predetermined distance to face the upper cooling plate and generating a cooling channel between the upper and lower cooling plates, characterized in that the main frame comprises: an upper groove provided along a circumferential direction, having a concave shape, and filled with an adhesive; and a lower groove provided below the upper groove, having a shape symmetrical to the upper groove, and filled with the adhesive, and wherein the upper bonding portion is bonded and fixed to the upper groove and the lower bonding portion is bonded and fixed to the lower groove, wherein an end of the upper bonding portion is bent downward and is inserted into the upper groove, and wherein an end of the lower bonding portion is bent upward and is inserted into the lower groove. a main frame comprising at least four unit frames (101,102) connected to each other at ends thereof to provide a cavity inside the four unit frames (101, 102), wherein at least some of the unit frames (101, 102) have openings penetrating therethrough in a horizontal direction and the main frame being configured to be vertically stackable on at least another main frame; an upper cooling plate having a plate shape, comprising an upper bonding portion serving as edges and bonded to the main frame, and arranged to cover the cavity; and a lower cooling plate having a plate shape, comprising a lower bonding portion serving as edges and bonded to the main frame, and spaced apart from the upper cooling plate by a predetermined distance to face the upper cooling plate and generating a cooling channel between the upper and lower cooling plates, characterized in that the main frame comprises: an upper groove provided along a circumferential direction, having a concave shape, and filled with an adhesive; and a lower groove provided below the upper groove, having a shape symmetrical to the upper groove, and filled with the adhesive, and wherein the upper bonding portion is bonded and fixed to the upper groove and the lower bonding portion is bonded and fixed to the lower groove, wherein an end of the upper bonding portion is bent downward and is inserted into the upper groove, and wherein an end of the lower bonding portion is bent upward and is inserted into the lower groove. an upper groove provided along a circumferential direction, having a concave shape, and filled with an adhesive; and a lower groove provided below the upper groove, having a shape symmetrical to the upper groove, and filled with the adhesive, and wherein the upper bonding portion is bonded and fixed to the upper groove and the lower bonding portion is bonded and fixed to the lower groove, wherein an end of the upper bonding portion is bent downward and is inserted into the upper groove, and wherein an end of the lower bonding portion is bent upward and is inserted into the lower groove.