A computer-implemented method for providing planning information for a neurosurgical procedure, the method comprising: receiving a first set of data characterizing the neurosurgical procedure, wherein the first set of data characterizing the neurosurgical procedure comprises a region of interest; accessing one or more historical databases containing historical data about historical procedures; determining one or more historical data relevant to the neurosurgical procedure, based on a determination of similarity to the first set of data, wherein determining the one or more historical data relevant to the neurosurgical procedure comprises determining one or more historical data associated with tissue analysis data similar to tissue analysis data associated with the neurosurgical procedure, and wherein the tissue analysis data includes Raman spectrum data; determining, from the one or more historical data, one or more historical instances of one or more procedure parameters relevant to the neurosurgical procedure, wherein the one or more procedure parameters include an entry site for the neurosurgical procedure, and wherein determining the one or more historical instances of the one or more procedure parameters comprises determining at least one tissue diagnosis associated with the one or more historical data; displaying, on an output device, the one or more historical instances of the one or more procedure parameters, wherein the displaying comprises displaying indicators of locations of one or more historical entry sites superimposed on an image of the region of interest for the neurosurgical procedure, and displaying, on the output device, one or more procedure outcomes associated with the one or more historical data. receiving a first set of data characterizing the neurosurgical procedure, wherein the first set of data characterizing the neurosurgical procedure comprises a region of interest; accessing one or more historical databases containing historical data about historical procedures; determining one or more historical data relevant to the neurosurgical procedure, based on a determination of similarity to the first set of data, wherein determining the one or more historical data relevant to the neurosurgical procedure comprises determining one or more historical data associated with tissue analysis data similar to tissue analysis data associated with the neurosurgical procedure, and wherein the tissue analysis data includes Raman spectrum data; determining, from the one or more historical data, one or more historical instances of one or more procedure parameters relevant to the neurosurgical procedure, wherein the one or more procedure parameters include an entry site for the neurosurgical procedure, and wherein determining the one or more historical instances of the one or more procedure parameters comprises determining at least one tissue diagnosis associated with the one or more historical data; displaying, on an output device, the one or more historical instances of the one or more procedure parameters, wherein the displaying comprises displaying indicators of locations of one or more historical entry sites superimposed on an image of the region of interest for the neurosurgical procedure, and displaying, on the output device, one or more procedure outcomes associated with the one or more historical data.