A method of synchronizing master medication configuration information within a pharmacy information system comprising a primary medication configuration computer (104, 204) with an ancillary medication management system (110, 210) comprising an ancillary medication configuration computer, comprising the steps of: receiving medication configuration change information from the primary medication configuration computer at the ancillary medication configuration computer, the medication configuration change information having been generated by the primary medication configuration computer in response to receiving medication configuration content from a medication configuration content source (106, 108); configuring filtering rules with a filtering rules configuration module, storing the filtering rules in a filtering rules repository, filtering the medication configuration change information by the ancillary medication configuration computer applying a configured filtering rule stored in the filtering rules repository within the ancillary medication configuration computer to generate filtered medication configuration change information, the configured filtering rule includes a criteria to be included or excluded from a repository; storing the filtered medication configuration change information in the repository; and, transmitting at least a portion of the filtered medication configuration change information to a management client computer, receiving an implementation decision on a trap management interface screen generated by repository management module about the portion of the filtered medication configuration change information at the ancillary medication configuration computer from the management client computer, wherein the implementation decision comprises accepting the portion of the filtered medication configuration change information to establish accepted filtered medication configuration change information, transmitting the accepted filtered medication configuration change information to at least one of a local formulary database and an ancillary clinical information system database; and integrating the accepted filtered medication configuration change information into at least one of the local formulary database and the ancillary clinical information system database, wherein the medication configuration information comprises formulary medication information. receiving medication configuration change information from the primary medication configuration computer at the ancillary medication configuration computer, the medication configuration change information having been generated by the primary medication configuration computer in response to receiving medication configuration content from a medication configuration content source (106, 108); configuring filtering rules with a filtering rules configuration module, storing the filtering rules in a filtering rules repository, filtering the medication configuration change information by the ancillary medication configuration computer applying a configured filtering rule stored in the filtering rules repository within the ancillary medication configuration computer to generate filtered medication configuration change information, the configured filtering rule includes a criteria to be included or excluded from a repository; storing the filtered medication configuration change information in the repository; and, transmitting at least a portion of the filtered medication configuration change information to a management client computer, receiving an implementation decision on a trap management interface screen generated by repository management module about the portion of the filtered medication configuration change information at the ancillary medication configuration computer from the management client computer, wherein the implementation decision comprises accepting the portion of the filtered medication configuration change information to establish accepted filtered medication configuration change information, transmitting the accepted filtered medication configuration change information to at least one of a local formulary database and an ancillary clinical information system database; and integrating the accepted filtered medication configuration change information into at least one of the local formulary database and the ancillary clinical information system database, wherein the medication configuration information comprises formulary medication information.