mhurhangee/ep-ind-claims huggingface dataset:
A method for producing a modified factor VII polypeptide (FVII), comprising: a) growing a cell that encodes the modified FVII polypeptide under conditions whereby the encoded modified FVII polypeptide is expressed, wherein: the modifications are at positions corresponding to position 286 and position 298 in a FVII polypeptide having the sequence of amino acids set forth in SEQ ID NO:3 or in corresponding positions at aligned loci in a FVII polypeptide, the modification at position 286 is an amino acid replacement with an arginine (Arg, R); the modification at position 298 is an amino acid replacement with a glutamine (Gln, Q); and the modified FVII polypeptide exhibits increased coagulant activity compared to an unmodified FVII polypeptide that does not have the modification at position 286; and b) recovering the expressed modified FVII polypeptide. a) growing a cell that encodes the modified FVII polypeptide under conditions whereby the encoded modified FVII polypeptide is expressed, wherein: the modifications are at positions corresponding to position 286 and position 298 in a FVII polypeptide having the sequence of amino acids set forth in SEQ ID NO:3 or in corresponding positions at aligned loci in a FVII polypeptide, the modification at position 286 is an amino acid replacement with an arginine (Arg, R); the modification at position 298 is an amino acid replacement with a glutamine (Gln, Q); and the modified FVII polypeptide exhibits increased coagulant activity compared to an unmodified FVII polypeptide that does not have the modification at position 286; and the modifications are at positions corresponding to position 286 and position 298 in a FVII polypeptide having the sequence of amino acids set forth in SEQ ID NO:3 or in corresponding positions at aligned loci in a FVII polypeptide, the modification at position 286 is an amino acid replacement with an arginine (Arg, R); the modification at position 298 is an amino acid replacement with a glutamine (Gln, Q); and the modified FVII polypeptide exhibits increased coagulant activity compared to an unmodified FVII polypeptide that does not have the modification at position 286; and b) recovering the expressed modified FVII polypeptide.
A method of manufacturing a steam turbine rotor which includes an ultra-high temperature side portion in which ultra-high temperature steam flows and a high temperature side portion in which high temperature steam flows, the steam turbine rotor manufacturing method comprising the steps of: preparing a first electrode having a solid structure and having a chemical composition corresponding to a chemical composition of a heat resistant alloy making up the ultra-high temperature side portion and a second electrode having a solid structure and having a chemical composition corresponding to a chemical composition of the high temperature side portion; providing joints on peripheral edges at longitudinal ends of the first and second electrodes, only the joints thereof are formed so as to provide a ring-shape or the joints thereof are configured such that only portions on an outer peripheral side of the electrodes protrude in an axial direction; tentatively joining together the joints of the first and second electrodes, with portions including the joints of the first and second electrodes made smaller in cross sectional area than other electrode portions; subjecting the tentatively joined first and second electrodes to electro-slag remelting, and forging a resulting electro-slag remelted ingot into a shape of a rotor to obtain a rotor forging; and subsequently heat-treating the rotor forging to obtain a rotor blank and manufacturing the steam turbine rotor from the rotor blank. preparing a first electrode having a solid structure and having a chemical composition corresponding to a chemical composition of a heat resistant alloy making up the ultra-high temperature side portion and a second electrode having a solid structure and having a chemical composition corresponding to a chemical composition of the high temperature side portion; providing joints on peripheral edges at longitudinal ends of the first and second electrodes, only the joints thereof are formed so as to provide a ring-shape or the joints thereof are configured such that only portions on an outer peripheral side of the electrodes protrude in an axial direction; tentatively joining together the joints of the first and second electrodes, with portions including the joints of the first and second electrodes made smaller in cross sectional area than other electrode portions; subjecting the tentatively joined first and second electrodes to electro-slag remelting, and forging a resulting electro-slag remelted ingot into a shape of a rotor to obtain a rotor forging; and subsequently heat-treating the rotor forging to obtain a rotor blank and manufacturing the steam turbine rotor from the rotor blank.
A lamp for a vehicle, comprising: a light source generating a light; a reflector rotatably coupled with a support; and a reflecting body connected to the reflector to rotate along with rotation of the reflector, the reflecting body receiving the light from the light source and reflecting the light to the reflector, characterized in that the reflecting body is rotatably axis-coupled with the support forward and backward, and the reflector and the reflecting body each having a set ratio are coupled with a reflector side gear and a reflecting body side gear which are meshed with each other. a light source generating a light; a reflector rotatably coupled with a support; and a reflecting body connected to the reflector to rotate along with rotation of the reflector, the reflecting body receiving the light from the light source and reflecting the light to the reflector, the reflecting body is rotatably axis-coupled with the support forward and backward, and the reflector and the reflecting body each having a set ratio are coupled with a reflector side gear and a reflecting body side gear which are meshed with each other.
Multilayer tube made from thermoplastic, which is obtainable by extrusion and at least comprises a core layer, which is surrounded by an inner layer and an outer layer, characterized in that the core layer comprises a plastics material with a melt flow index value (MFI value) which is higher than the MFI value of the plastic of both the inner layer and the outer layer if the MFI values are measured under the same conditions, wherein the core layer comprises a plastic with an MFI value which is 1.5 to 20x the lowest MFI value of the plastic of the other layers (2, 3). wherein the core layer comprises a plastic with an MFI value which is 1.5 to 20x the lowest MFI value of the plastic of the other layers (2, 3).
An implant delivery system, comprising an inner tube assembly, an outer tube assembly and a functional handle, wherein the inner tube assembly comprises, from a proximal end to a distal end in the sequence set forth, a reinforcing tube, a proximal inner tube, a stent ear holder, a distal inner tube and a tip; the inner tube assembly is configured to allow a guide wire to extend therethrough; the outer tube assembly is disposed over the inner tube assembly and comprises, from a proximal end to a distal end, a proximal outer tube and a stent capsule, the proximal outer tube being received within a stability tube; the functional handle is connected to both the inner tube assembly and the outer tube assembly and the functional handle comprises a threaded rod, a push-pull control member, a casing tube, a displacement tube, an inner tube fixing member, an outer tube fixing member and a stability tube fixing member, the inner tube fixing member being in fixed connection with a proximal portion of the inner tube assembly; the outer tube fixing member being in fixed connection both with a proximal end of the outer tube assembly and with a distal end of the displacement tube, the stability tube fixing member being in fixed connection with a proximal end of the stability tube and fixed to a distal end of the casing tube; the displacement tube is received within the casing tube such that the displacement tube moves forward and backward in the casing tube only along its axis direction; the threaded rod extends through a bore of the displacement tube; the threaded rod defines a leading portion and a trailing portion, the trailing portion of the threaded rod being provided with a knob; the push-pull control member comprises a fastener and a button, the button being provided on the fastener; the displacement tube defines a slot compatible with the fastener, and the fastener is able to extend through the slot to engage a thread of the threaded rod in the displacement tube; the push-pull control member further comprises a cylindrical shell and springs, and the cylindrical shell is disposed over the casing tube such that the button is able to extend out of the cylindrical shell through an opening thereof; the fastener assumes an annular shape and is engageable with the thread provided on the leading portion of the threaded rod; and the springs are disposed between the fastener and the displacement tube and configured to cause an automatic locking of the fastener and the threaded rod.
An antenna assembly (200, 301, 401, 1201, 1301) and a window, the antenna assembly integrated with the window and comprising: an antenna array (201, 1200, 1300); a film layer (221, 1010, 1110, 1112, 1114) made of at least one insulating substance, spaced a predetermined first distance apart from the antenna array, and bonded to a surface of the window; an assistant installation structure (241, 331, 411) having a first surface attached and fixed to the window and a second surface on which an antenna array seat is formed to which the antenna array is coupled; and a lens (211, 1210, 1310) spaced a predetermined second distance from the antenna array and disposed between the antenna array and the film layer, wherein a seat for the lens is formed on the second surface of the assistant installation structure. an antenna array (201, 1200, 1300); a film layer (221, 1010, 1110, 1112, 1114) made of at least one insulating substance, spaced a predetermined first distance apart from the antenna array, and bonded to a surface of the window; an assistant installation structure (241, 331, 411) having a first surface attached and fixed to the window and a second surface on which an antenna array seat is formed to which the antenna array is coupled; and a lens (211, 1210, 1310) spaced a predetermined second distance from the antenna array and disposed between the antenna array and the film layer, wherein a seat for the lens is formed on the second surface of the assistant installation structure.
A method for printing a desired one-dimensional or two-dimensional periodic pattern of features into a photosensitive layer, which method includes: a) providing a mask bearing a periodic mask pattern of features; b) providing a substrate bearing the photosensitive layer; c) arranging the substrate substantially parallel to and with a separation from the mask; d) forming a beam of collimated monochromatic light for illuminating said mask pattern so that the light-field transmitted by the mask forms Talbot image planes separated by a Talbot distance; and characterized in that the method includes: f) performing N sub-exposures of the mask with said beam and changing the separation between sub-exposures such that the relative separation during the ith sub-exposure with respect to that during the first sub-exposure is given by (m i + n i /N) times the Talbot distance, where m i is an integer and n i takes each of the integer values from 0 to N-1 for the different sub-exposures; wherein the period is selected in relation to the wavelength of illumination so that substantially only the zeroth and first diffraction orders are transmitted by the mask. a) providing a mask bearing a periodic mask pattern of features; b) providing a substrate bearing the photosensitive layer; c) arranging the substrate substantially parallel to and with a separation from the mask; d) forming a beam of collimated monochromatic light for illuminating said mask pattern so that the light-field transmitted by the mask forms Talbot image planes separated by a Talbot distance; and characterized in that the method includes: f) performing N sub-exposures of the mask with said beam and changing the separation between sub-exposures such that the relative separation during the ith sub-exposure with respect to that during the first sub-exposure is given by (m i + n i /N) times the Talbot distance, where m i is an integer and n i takes each of the integer values from 0 to N-1 for the different sub-exposures; f) performing N sub-exposures of the mask with said beam and changing the separation between sub-exposures such that the relative separation during the ith sub-exposure with respect to that during the first sub-exposure is given by (m i + n i /N) times the Talbot distance, where m i is an integer and n i takes each of the integer values from 0 to N-1 for the different sub-exposures;
An incubator, such as an infant incubator, a chicken incubator or a glove box comprising a PCM-based heat exchanger comprising: a) a case having insulated walls comprising an inlet and an outlet; and b) a plurality of modules comprising a support structure containing a PCM characterised in that said modules are arranged within said case in a way as to define a single, one way fluidic path connecting said inlet with said outlet. a) a case having insulated walls comprising an inlet and an outlet; and b) a plurality of modules comprising a support structure containing a PCM
A method of manufacturing ordered Alloy 690 with improved thermal conductivity, the method comprising: solution-annealing Alloy 690; cooling the solution-annealed Alloy 690 to a first temperature at a cooling rate of 200 °C/min or less; and ordering the cooled Alloy 690 by annealing at a temperature ranging from 410 to 520 °C. solution-annealing Alloy 690; cooling the solution-annealed Alloy 690 to a first temperature at a cooling rate of 200 °C/min or less; and ordering the cooled Alloy 690 by annealing at a temperature ranging from 410 to 520 °C.
Method of labelling containers with sleeve labels, whereby the sleeve labels are ejected from above onto circulating spreading units having spreading jaws which can be moved apart from one another, characterised in that the sleeve labels are decelerated before making a bottom abutting contact with the spreading units by being sucked onto at least one of the spreading jaws and/or by moving the spreading jaws apart from one another.
An aeration diffuser (12, 14) for a pressurized liquid treatment module, having a plurality of tubular filtration membranes fixed in the module by a potting section, the diffuser comprising: a base having a gas passageway, a liquid passageway fluidically separated from the gas passageway, a central hub, and at least two channels extending radially outwardly from the hub, each channel being in fluid communication with the gas passageway and fluidically separated from the liquid passageway, each channel having at least one opening to aerate the at least one filtration membrane within the module, and an adapter including a gas passageway having a gas inlet and a liquid passageway having a liquid inlet and being fluidically separated from the gas passageway, the adapter being fixed to the hub, such that the gas passageway of the adapter is in fluid communication with the gas passageway of the base and the liquid passageway of the adapter is in fluid communication with the liquid passageway of the base, wherein liquid is injectable into the liquid passageway of the base, the liquid flowing axially through the hub and into the module on one side of the filtration membranes to be filtered by the filtration membranes within the module, and wherein gas is injectable into the gas passageway of the base, the gas flowing through the hub and out of the diffuser through the openings of the at least two channels to aerate the one side of the filtration membranes within the module. a base having a gas passageway, a liquid passageway fluidically separated from the gas passageway, a central hub, and at least two channels extending radially outwardly from the hub, each channel being in fluid communication with the gas passageway and fluidically separated from the liquid passageway, each channel having at least one opening to aerate the at least one filtration membrane within the module, and an adapter including a gas passageway having a gas inlet and a liquid passageway having a liquid inlet and being fluidically separated from the gas passageway, the adapter being fixed to the hub, such that the gas passageway of the adapter is in fluid communication with the gas passageway of the base and the liquid passageway of the adapter is in fluid communication with the liquid passageway of the base, wherein liquid is injectable into the liquid passageway of the base, the liquid flowing axially through the hub and into the module on one side of the filtration membranes to be filtered by the filtration membranes within the module, and wherein gas is injectable into the gas passageway of the base, the gas flowing through the hub and out of the diffuser through the openings of the at least two channels to aerate the one side of the filtration membranes within the module.
A method of performing transmission for a user equipment, UE, for a wireless communication system, the method comprising: receiving, by the UE, a plurality of configured grants, wherein the receiving comprises receiving a configured grant for at least one service configured in a single bandwidth part, BWP; verifying, by the UE, whether an overlap occurs between the plurality of configured grants, wherein the verifying comprises verifying whether transmission points for transmitting traffic are overlapped in time; characterized by selecting, by the UE, a first configured grant from among a plurality of overlapped configured grants, wherein the selecting of the first configured grant is based on a priority for a logical channel corresponding to the first configured grant, and wherein the priority is indicated by a radio resource control, RRC, message received from a base station; and transmitting, using the first configured grant, traffic associated with the logical channel. receiving, by the UE, a plurality of configured grants, wherein the receiving comprises receiving a configured grant for at least one service configured in a single bandwidth part, BWP; verifying, by the UE, whether an overlap occurs between the plurality of configured grants, wherein the verifying comprises verifying whether transmission points for transmitting traffic are overlapped in time; characterized by selecting, by the UE, a first configured grant from among a plurality of overlapped configured grants, wherein the selecting of the first configured grant is based on a priority for a logical channel corresponding to the first configured grant, and wherein the priority is indicated by a radio resource control, RRC, message received from a base station; and transmitting, using the first configured grant, traffic associated with the logical channel.
A compound vaccine of micellar nanoparticles for mucosal intranasal administration comprising as immunogen a Y-helix peptide that corresponds to the carboxy-end 11 amino acid sequence of CETP added with a Cys residue in the amino-end of said peptide; and archaebacteria membrane lipids, 1-Lauroyl-2-hydroxy- sn -glycero-3-phosphocholine (Lyso C12) and L-α-phosphatidylcholine as structural lipids, in a pharmaceutically acceptable vehicle.
A method for wireless communication, comprising: reporting, by a terminal, at a first protocol layer, a first event to a second protocol layer, wherein the first event is used to indicate that quality of a signal in a first signal set is bad enough to satisfy a first condition; wherein the first protocol layer is a physical layer, and the second protocol layer is a Media Access Control, MAC, layer; determining, by the terminal, at the second protocol layer, occurrence of a second event when a number of times that the first event has successively occurred within a specific time period exceeds a threshold; sending, by the terminal, second indication information to the first protocol layer from the second protocol layer, wherein the second indication information is used to indicate reporting a signal in a second signal set, of which signal quality is good enough to satisfy a third condition; and responsive to the second indication information, sending, by the terminal, a first message to a network device, wherein the first message is used to indicate the signal in the second signal set, of which the signal quality is good enough to satisfy the third condition; wherein occurrence of the first event comprises occurrence of beam failure instance, the occurrence of the second event comprises occurrence of beam failure, and the second event is used to indicate that link quality corresponding to the signal in the first signal set is bad enough to satisfy a second condition. reporting, by a terminal, at a first protocol layer, a first event to a second protocol layer, wherein the first event is used to indicate that quality of a signal in a first signal set is bad enough to satisfy a first condition; wherein the first protocol layer is a physical layer, and the second protocol layer is a Media Access Control, MAC, layer; determining, by the terminal, at the second protocol layer, occurrence of a second event when a number of times that the first event has successively occurred within a specific time period exceeds a threshold; sending, by the terminal, second indication information to the first protocol layer from the second protocol layer, wherein the second indication information is used to indicate reporting a signal in a second signal set, of which signal quality is good enough to satisfy a third condition; and responsive to the second indication information, sending, by the terminal, a first message to a network device, wherein the first message is used to indicate the signal in the second signal set, of which the signal quality is good enough to satisfy the third condition; wherein occurrence of the first event comprises occurrence of beam failure instance, the occurrence of the second event comprises occurrence of beam failure, and the second event is used to indicate that link quality corresponding to the signal in the first signal set is bad enough to satisfy a second condition.
A method of manufacturing a thin film transistor comprising a substrate; a source and a drain electrode that are mutually separated by a channel, and a gate electrode that is isolated from the channel through a gate insulating layer, wherein the gate electrode is formed on the island-shaped channel with the gate insulating layer (260 being interposed therebetween, the channel being formed comprising the steps of applying a channel forming layer and photolithographical patterning of the channel forming layer with a mask, wherein the substrate is transparent and is provided with the mask for patterning the channel forming layer, the mask being a shield layer to prevent light from entering the channel, characterized by providing the source and drain electrodes on the substrate, onto which the channel forming layer is applied; oxidizing side faces of said channel comprising amorphous silicon, and forming said gate electrode on said channel having the oxidized side faces with the gate insulating layer being interposed therebetween.
Immunostimulatory composition comprising a) an adjuvant component, comprising or consisting of at least one mRNA, complexed with protamine, and b) at least one free mRNA, encoding at least one antigen, wherein the at least one mRNA of component (a) and the at least one free mRNA of component (b) are identical to each other, and wherein the immunostimulatory composition is capable to elicit or enhance an innate and optionally an adaptive immune response in a mammal. a) an adjuvant component, comprising or consisting of at least one mRNA, complexed with protamine, and b) at least one free mRNA, encoding at least one antigen,