An imidazole derivative of Formula 1 or a pharmaceutically acceptable salt thereof, wherein: in the Formula 1 above, R 1 is C 4 -C 10 aryl, C 4 -C 10 heteroaryl, or C 4 -C 10 heterocycloalkyl, wherein C 4 -C 10 aryl and C 4 -C 10 heteroaryl are ones selected from the group consisting of phenyl, naphthyl, pyrenyl, carbazolyl, benzoxazolyl, benzodioxazolyl, 1,3-benzodioxolyl, 1,4-benzodioxinyl, benzothiazolyl, benzoimidazolyl, benzothiophenyl, quinolinyl, isoquinolinyl, indolyl, benzofuranyl, purinyl and indolizinyl, wherein C 4 -C 10 heterocycloalkyl is one selected from the group consisting of tetrahydrofuranyl, tetrahydrothiophenyl, pyrrolidinyl, tetrahydropyranyl, tetrahydrothiopyranyl, piperidinyl and dihydrobenzodioxinyl, and wherein R 1 may be unsubstituted or substituted with at least one substituent selected from the group consisting of C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, hydroxy, amino and halogen; and R 2 is C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 2 -C 6 alkoxy, C 1 -C 6 alcohol, C 3 -C 10 cycloalkyl, or C 4 -C 10 heterocycloalkyl, wherein C 4 -C 10 heterocycloalkyl is one selected from the group consisting of tetrahydrofuranyl, tetrahydrothiophenyl, pyrrolidinyl, tetrahydropyranyl, tetrahydrothiopyranyl, piperidinyl and dihydrobenzodioxinyl, and wherein R 2 may be unsubstituted or substituted with at least one substituent selected from the group consisting of C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, hydroxy, amino, halogen, C 2 -C 10 alkylcarbonyl, and C 4 -C 10 cycloalkylcarbonyl. R 1 is C 4 -C 10 aryl, C 4 -C 10 heteroaryl, or C 4 -C 10 heterocycloalkyl, wherein C 4 -C 10 aryl and C 4 -C 10 heteroaryl are ones selected from the group consisting of phenyl, naphthyl, pyrenyl, carbazolyl, benzoxazolyl, benzodioxazolyl, 1,3-benzodioxolyl, 1,4-benzodioxinyl, benzothiazolyl, benzoimidazolyl, benzothiophenyl, quinolinyl, isoquinolinyl, indolyl, benzofuranyl, purinyl and indolizinyl, wherein C 4 -C 10 heterocycloalkyl is one selected from the group consisting of tetrahydrofuranyl, tetrahydrothiophenyl, pyrrolidinyl, tetrahydropyranyl, tetrahydrothiopyranyl, piperidinyl and dihydrobenzodioxinyl, and wherein R 1 may be unsubstituted or substituted with at least one substituent selected from the group consisting of C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, hydroxy, amino and halogen; and wherein C 4 -C 10 aryl and C 4 -C 10 heteroaryl are ones selected from the group consisting of phenyl, naphthyl, pyrenyl, carbazolyl, benzoxazolyl, benzodioxazolyl, 1,3-benzodioxolyl, 1,4-benzodioxinyl, benzothiazolyl, benzoimidazolyl, benzothiophenyl, quinolinyl, isoquinolinyl, indolyl, benzofuranyl, purinyl and indolizinyl, wherein C 4 -C 10 heterocycloalkyl is one selected from the group consisting of tetrahydrofuranyl, tetrahydrothiophenyl, pyrrolidinyl, tetrahydropyranyl, tetrahydrothiopyranyl, piperidinyl and dihydrobenzodioxinyl, and wherein R 1 may be unsubstituted or substituted with at least one substituent selected from the group consisting of C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, hydroxy, amino and halogen; and R 2 is C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 2 -C 6 alkoxy, C 1 -C 6 alcohol, C 3 -C 10 cycloalkyl, or C 4 -C 10 heterocycloalkyl, wherein C 4 -C 10 heterocycloalkyl is one selected from the group consisting of tetrahydrofuranyl, tetrahydrothiophenyl, pyrrolidinyl, tetrahydropyranyl, tetrahydrothiopyranyl, piperidinyl and dihydrobenzodioxinyl, and wherein R 2 may be unsubstituted or substituted with at least one substituent selected from the group consisting of C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, hydroxy, amino, halogen, C 2 -C 10 alkylcarbonyl, and C 4 -C 10 cycloalkylcarbonyl. wherein C 4 -C 10 heterocycloalkyl is one selected from the group consisting of tetrahydrofuranyl, tetrahydrothiophenyl, pyrrolidinyl, tetrahydropyranyl, tetrahydrothiopyranyl, piperidinyl and dihydrobenzodioxinyl, and wherein R 2 may be unsubstituted or substituted with at least one substituent selected from the group consisting of C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, hydroxy, amino, halogen, C 2 -C 10 alkylcarbonyl, and C 4 -C 10 cycloalkylcarbonyl.