mhurhangee/ep-ind-claims huggingface dataset:
A compound, or a pharmaceutically acceptable salt thereof, having the structure of Formula: wherein: ring is an aryl ring or heteroaryl ring; X is a bond, -O-, -S-, or -N(R 6)-; R 1 is -CO 2 H or each R 2 is independently halogen, -OR 5, NO 2, substituted or unsubstituted C 1 -C 6 alkyl, or substituted or unsubstituted C 1 -C 6 fluoroalkyl; each R 3 is independently halogen, -OR 5, -SR 5, substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 1 -C 6 fluoroalkyl, substituted or unsubstituted C 3 -C 6 cycloalkyl, or substituted or unsubstituted aryl; R 4 is H, -CF 3, -CH 3, or substituted or unsubstituted phenyl; each R 5 is independently hydrogen, or substituted or unsubstituted C 1 -C 6 alkyl; R 6 is hydrogen, or substituted or unsubstituted C 1 -C 6 alkyl; wherein "substituted" means that the referenced group may be substituted with one or more additional group(s) individually and independently selected from alkyl, alkoxy, haloalkyl, cycloalkyl, halogen, -CN, -NH 2, -NH(CH 3), -N(CH 3) 2, -OH, -CO 2 H, and -CO 2 alkyl; n is 0, 1, 2, or 3; and m is 0, 1 or 2. ring is an aryl ring or heteroaryl ring; X is a bond, -O-, -S-, or -N(R 6)-; R 1 is -CO 2 H or each R 2 is independently halogen, -OR 5, NO 2, substituted or unsubstituted C 1 -C 6 alkyl, or substituted or unsubstituted C 1 -C 6 fluoroalkyl; each R 3 is independently halogen, -OR 5, -SR 5, substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted C 1 -C 6 fluoroalkyl, substituted or unsubstituted C 3 -C 6 cycloalkyl, or substituted or unsubstituted aryl; R 4 is H, -CF 3, -CH 3, or substituted or unsubstituted phenyl; each R 5 is independently hydrogen, or substituted or unsubstituted C 1 -C 6 alkyl; R 6 is hydrogen, or substituted or unsubstituted C 1 -C 6 alkyl; wherein "substituted" means that the referenced group may be substituted with one or more additional group(s) individually and independently selected from alkyl, alkoxy, haloalkyl, cycloalkyl, halogen, -CN, -NH 2, -NH(CH 3), -N(CH 3) 2, -OH, -CO 2 H, and -CO 2 alkyl; n is 0, 1, 2, or 3; and m is 0, 1 or 2.
A pressure vessel system, comprising: a pressure element configured to store compressed gas; a shell configured to enclose the pressure element and capture the compressed gas that permeates from the pressure element; an end fitting extending into a cavity of the pressure element and from the pressure element through the shell, the end fitting comprising: a stem that extends out from the shell in one direction and into the cavity of the pressure element in an opposite direction; and a cap (1506, 1507) that surrounds the pressure element and the stem at a location external to the pressure element; and a retention component configured to sustain engagement of the end fitting with at least one of the pressure element or the shell below a predetermined pressure threshold; wherein the retention component comprises: a tether with a first end coupled to the stem at a location external to the shell and a second end coupled to a curved portion of another pressure element interior to the shell. a pressure element configured to store compressed gas; a shell configured to enclose the pressure element and capture the compressed gas that permeates from the pressure element; an end fitting extending into a cavity of the pressure element and from the pressure element through the shell, the end fitting comprising: a stem that extends out from the shell in one direction and into the cavity of the pressure element in an opposite direction; and a cap (1506, 1507) that surrounds the pressure element and the stem at a location external to the pressure element; and a stem that extends out from the shell in one direction and into the cavity of the pressure element in an opposite direction; and a cap (1506, 1507) that surrounds the pressure element and the stem at a location external to the pressure element; and a retention component configured to sustain engagement of the end fitting with at least one of the pressure element or the shell below a predetermined pressure threshold; wherein the retention component comprises: a tether with a first end coupled to the stem at a location external to the shell and a second end coupled to a curved portion of another pressure element interior to the shell.
A monolithic implant comprising (i) a luteinizing hormone releasing hormone analogue (= LH-RH analogue) selected from the group consisting of Leuprorelin, Buserelin, Triptorelin, Nafarelin, Gonadorelin, Cetrorelix, Ganirelix, or a pharmaceutically acceptable salt thereof in an amount of less than 25% per weight of the total composition and (ii) a homogenous polylactide polymer consisting solely of lactic acid monomers and having a polydispersity index of 1.2 to 2.2, being resistant to degradation caused by gamma-radiation and/or temperature stress, wherein the degradation-resistant polylactide polymer shows a degree of decomposition of less than 1000 Dalton relative to the weight-average molecular weight of the polymer after gamma-irradiation is performed with an irradiation dose of between about 25 and 40 kGy of ionising gamma-radiation and/or wherein the degradation-resistant polylactide polymer shows a degree of decomposition of less than 1000 Dalton relative to the weight-average molecular weight of the polymer after temperature stress, at a temperature of about 30°C over a period of at least 24 month, wherein the polylactide polymer has a weight-average molecular weight of 4800 to 8600 Dalton. (i) a luteinizing hormone releasing hormone analogue (= LH-RH analogue) selected from the group consisting of Leuprorelin, Buserelin, Triptorelin, Nafarelin, Gonadorelin, Cetrorelix, Ganirelix, or a pharmaceutically acceptable salt thereof in an amount of less than 25% per weight of the total composition and (ii) a homogenous polylactide polymer consisting solely of lactic acid monomers and having a polydispersity index of 1.2 to 2.2, being resistant to degradation caused by gamma-radiation and/or temperature stress, wherein the degradation-resistant polylactide polymer shows a degree of decomposition of less than 1000 Dalton relative to the weight-average molecular weight of the polymer after gamma-irradiation is performed with an irradiation dose of between about 25 and 40 kGy of ionising gamma-radiation and/or wherein the degradation-resistant polylactide polymer shows a degree of decomposition of less than 1000 Dalton relative to the weight-average molecular weight of the polymer after temperature stress, at a temperature of about 30°C over a period of at least 24 month,
A method for producing a pattern structure by means of a polymer (1,4) deposited on a support, such method successively comprising: - forming, on the support, polymer sites which preferably react with a predetermined plasma, by preventing the deposit of a dielectric material by said plasma on said sites, - depositing, on the support, a dielectric material by said plasma, the polymer sites reacting with the plasma by preventing the deposit of the dielectric material at the level of said sites, so as to form openings (6,7) at the level of said sites. - forming, on the support, polymer sites which preferably react with a predetermined plasma, by preventing the deposit of a dielectric material by said plasma on said sites, - depositing, on the support, a dielectric material by said plasma, the polymer sites reacting with the plasma by preventing the deposit of the dielectric material at the level of said sites, so as to form openings (6,7) at the level of said sites.
A computer-implemented method for outputting a stimulation history map corresponding to a plurality of stimulations that have been performed using a stimulation device (200; 1200) implanted in an anatomical region, the method comprising: for each of a plurality of display elements, where each of the display elements is recorded as having been part of a plurality of scored estimated volumes of tissue activated (VOAs) by the plurality of stimulations, determining, by a computer processor, a score for the display element based on scores of the plurality of VOAs of which the display element has been recorded as being a part; and generating and outputting, by the processor, a map (800; 802; 808; 810; 1204; 1205) including the plurality of display elements graphically marked based on the respective scores determined for the display elements. for each of a plurality of display elements, where each of the display elements is recorded as having been part of a plurality of scored estimated volumes of tissue activated (VOAs) by the plurality of stimulations, determining, by a computer processor, a score for the display element based on scores of the plurality of VOAs of which the display element has been recorded as being a part; and generating and outputting, by the processor, a map (800; 802; 808; 810; 1204; 1205) including the plurality of display elements graphically marked based on the respective scores determined for the display elements.
A one-way valve for use in the inhalation or exhalation flowpath of respiratory protection equipment comprising a conduit and a circumferential array of at least three flexible flaps each extending inwards of the conduit from the wall thereof and away from the inlet end of the valve in the unflexed condition of the flaps, and wherein each flap is fixed directly to the conduit along an arcuate edge whereby under a pressure differential in the opening direction of the valve each said flap is adapted to flex outwards towards the wall of the conduit and under a reverse pressure differential the free edge of each said flap is adapted to press in sealing contact with respective portions of the free edges of the neighbouring said flaps, and to effect a seal without need for a seat for the flaps to seal against.
Compound of formula: wherein X is (CH 2)n; Y is selected from (CH 2) m, para substituted phenyl; Z is (CH 2) p; n is an integer 0 to 4; m is an integer 1 to 8; p is an integer 0 to 4; A is selected from the following groups: B is selected from Br, Cl, I, F, Methyl, Isopropyl, tert-butyl, substituted or unsubstituted aryl or heteroaryl (Ar) group, wherein Ar is selected from benzene, furan, thiophene, pyrrolidine, pyrrole, 1,2,3-triazole, pyrazole, imidazole, oxazole, isooxazole, thiazole, isothiazole, 1,2,3-oxadiazole, 1,2,4-oxadiazole, 1,2,5-oxadiazole, pyridine, pyridazine, pyrimidine, pyrazine, naphthalene, indole, 1 H -indazole, 1 H -benzo[d]imidazole, benzofuran, benzothiophene, quinoline, isoquinoline, quinoxaline, or carbazole, and wherein when B is selected from a substituted aryl or heteroaryl (Ar) group, the one or more substituents are independently selected from -COOH, -NH 2, - COOR 1, -CONH 2, -CONHR 1, -CONR 1 R 2, -R 3; wherein R 1 and R 2 are identical or different from each other and independently selected from -H, straight or branched, unsubstituted C 1-8 alkyl, unsubstituted C 3-6 cycloalkyl, R 3 is selected from straight or branched, unsubstituted C 1-8 alkyl, unsubstituted C 3-6 cycloalkyl; pharmaceutically acceptable, hydrate, solvate or salt thereof. X is (CH 2)n; Y is selected from (CH 2) m, para substituted phenyl; Z is (CH 2) p; n is an integer 0 to 4; m is an integer 1 to 8; p is an integer 0 to 4; A is selected from the following groups: B is selected from Br, Cl, I, F, Methyl, Isopropyl, tert-butyl, substituted or unsubstituted aryl or heteroaryl (Ar) group, wherein Ar is selected from benzene, furan, thiophene, pyrrolidine, pyrrole, 1,2,3-triazole, pyrazole, imidazole, oxazole, isooxazole, thiazole, isothiazole, 1,2,3-oxadiazole, 1,2,4-oxadiazole, 1,2,5-oxadiazole, pyridine, pyridazine, pyrimidine, pyrazine, naphthalene, indole, 1 H -indazole, 1 H -benzo[d]imidazole, benzofuran, benzothiophene, quinoline, isoquinoline, quinoxaline, or carbazole, and wherein when B is selected from a substituted aryl or heteroaryl (Ar) group, the one or more substituents are independently selected from -COOH, -NH 2, - COOR 1, -CONH 2, -CONHR 1, -CONR 1 R 2, -R 3; R 1 and R 2 are identical or different from each other and independently selected from -H, straight or branched, unsubstituted C 1-8 alkyl, unsubstituted C 3-6 cycloalkyl, R 3 is selected from straight or branched, unsubstituted C 1-8 alkyl, unsubstituted C 3-6 cycloalkyl; pharmaceutically acceptable, hydrate, solvate or salt thereof.
A method of treating a catheter, comprising: moving an expander longitudinally within a lumen of a catheter, while the catheter is outside a patient, wherein the expander comprises a control wire and a rigid enlarging member at a distal portion of the control wire, wherein an outer cross-sectional dimension of the enlarging member is (i) between 0.0051 mm and 0.0152 mm (0.0002" and 0.0006") larger than a first inner cross-sectional dimension of the lumen in an unrestrained condition and/or (ii) between 1% and 3% larger than the first inner cross-sectional dimension of the lumen, wherein the moving comprises passing the enlarging member from a first location distal to a distal end of the catheter to a second location proximal to a proximal end of the catheter. moving an expander longitudinally within a lumen of a catheter, while the catheter is outside a patient, wherein the expander comprises a control wire and a rigid enlarging member at a distal portion of the control wire, wherein an outer cross-sectional dimension of the enlarging member is (i) between 0.0051 mm and 0.0152 mm (0.0002" and 0.0006") larger than a first inner cross-sectional dimension of the lumen in an unrestrained condition and/or (ii) between 1% and 3% larger than the first inner cross-sectional dimension of the lumen, wherein the moving comprises passing the enlarging member from a first location distal to a distal end of the catheter to a second location proximal to a proximal end of the catheter.
Method for accessing a radio channel in a communication system comprising a plurality of terminals communicating with one another by radio links, a terminal being equipped with transmission and/or reception means (11n, 12n), a processor adapted for executing the steps of the method, said method using an access protocol based on a communication frame made up of a plurality of slots S,.., S(S+2), the first S slots each comprising two mini-slots, the first mini-slot MS1 comprising a request to send data signalling message RTS or data, the second mini-slot MS2 comprising a "ready to receive" signalling message, CTS, or data, the slot (S+1) containing a message of RTS type or data, the slot (S+2) containing a message of CTS type and an acknowledgement message placed at the end of the frame in order to acknowledge one or more transmissions taking place on the radio channel.
Switchgear having an enclosure housing and anchoring points (7a, 7b, 7c, 7d), wherein the enclosure housing has a flange, beyond the circumference of which the anchoring points (7a, 7b, 7c, 7d) project, characterized in that the anchoring points (7a, 7b, 7c, 7d) are arranged such that the centre of gravity of the switchgear is located below the anchoring points (7a, 7b, 7c, 7d), between the anchoring points (7a, 7b, 7c, 7d) and a counter-bearing for the anchoring forces, in the anchoring direction, wherein the anchoring direction is located in a vertical direction and is determined by the sum of the forces which act on the switchgear, and the flange is closed by a gear cover.
A sensor device comprising: a housing placed at least in part on top of a soil surface; at least one battery housed within a battery compartment in the housing, wherein the battery compartment is at least partly submerged into the soil surface; a sensor electrically coupled with the at least one battery; the battery is housed in an upright position within the battery compartment, wherein the sensor is electrically connected to a secondary PCB and/or an antenna; characterized in that: the housing has a top cover and a battery cover, to allow for the insertion of the at least one battery into the housing the battery cover is removable, while being used to cover the housing from below when installed. a housing placed at least in part on top of a soil surface; at least one battery housed within a battery compartment in the housing, wherein the battery compartment is at least partly submerged into the soil surface; a sensor electrically coupled with the at least one battery; the battery is housed in an upright position within the battery compartment, wherein the sensor is electrically connected to a secondary PCB and/or an antenna; characterized in that: the housing has a top cover and a battery cover, to allow for the insertion of the at least one battery into the housing the battery cover is removable, while being used to cover the housing from below when installed. the housing has a top cover and a battery cover, to allow for the insertion of the at least one battery into the housing the battery cover is removable, while being used to cover the housing from below when installed.
A system for reducing carbon dioxide emissions from a flue gas generated via combusting a fossil fuel, the system comprising: a calcination chamber configured to receive a plurality of loaded sorbent particles and a plurality of heat-transferring particles such that the loaded sorbent particles are heated within the calcination chamber so as to release carbon dioxide; a sealing-purger (90, 92) that includes at least one gravity driven moving particle bed (106, 132); and wherein the at least one gravity driven moving particle bed (106, 132) allows the plurality of heat-transferring particles or the plurality of sorbent particles to enter or leave the calcination chamber while restricting the flue gas from entering the calcination chamber and the released carbon dioxide from leaving the calcination chamber, wherein a height of the at least one gravity driven moving particle bed is adjustable by a flow restriction device based at least in part on a pressure gradient across the at least one gravity driven moving particle bed. a calcination chamber configured to receive a plurality of loaded sorbent particles and a plurality of heat-transferring particles such that the loaded sorbent particles are heated within the calcination chamber so as to release carbon dioxide; a sealing-purger (90, 92) that includes at least one gravity driven moving particle bed (106, 132); and wherein the at least one gravity driven moving particle bed (106, 132) allows the plurality of heat-transferring particles or the plurality of sorbent particles to enter or leave the calcination chamber while restricting the flue gas from entering the calcination chamber and the released carbon dioxide from leaving the calcination chamber, wherein a height of the at least one gravity driven moving particle bed is adjustable by a flow restriction device based at least in part on a pressure gradient across the at least one gravity driven moving particle bed.
A household appliance with a component part (12,18) containing a polymer and at least one polyoxometalate, characterized in that the polyoxometalate is anchored to a silica containing substrate.
A covering for an architectural opening, comprising: a rotatable roller; a shade suspended from the roller and wrappable about the roller; and an assembly associated with the roller comprising a biasing element associated with the roller and a retention element associated with the biasing element, characterized in that the biasing element is configured to selectively rotate the roller in an extension direction, the biasing element being preloaded with a resilient force and remaining in a preloaded state until the shade reaches a predetermined extended position; and in that the retention element is configured to release the preload at the predetermined extended position such that the assembly rotates the roller a supplemental amount in the extension direction when the shade reaches the predetermined extended position. a rotatable roller; a shade suspended from the roller and wrappable about the roller; and an assembly associated with the roller comprising a biasing element associated with the roller and a retention element associated with the biasing element, characterized in that the biasing element is configured to selectively rotate the roller in an extension direction, the biasing element being preloaded with a resilient force and remaining in a preloaded state until the shade reaches a predetermined extended position; and in that the retention element is configured to release the preload at the predetermined extended position such that the assembly rotates the roller a supplemental amount in the extension direction when the shade reaches the predetermined extended position. a biasing element associated with the roller and a retention element associated with the biasing element, characterized in that the biasing element is configured to selectively rotate the roller in an extension direction, the biasing element being preloaded with a resilient force and remaining in a preloaded state until the shade reaches a predetermined extended position; and in that the retention element is configured to release the preload at the predetermined extended position such that the assembly rotates the roller a supplemental amount in the extension direction when the shade reaches the predetermined extended position.
Apparatus for fixing railway rails to a substructure (20; 20a, 20b), comprising to each fixing point: - two angle guide elements (30; 30a, 30b) which are disposed on both sides of the rail foot; - one supporting element on the side of each angle guide element (30; 30a, 30b) facing away from the rail foot; - two screw bolts for tightening rail clamps which are disposed so as to extend through openings in the angle guide plates (30; 30a, 30b) in the assembled state; and - a base unit which is disposed under the angle guide elements (30; 30a, 30b) and supporting elements of the fixing point; characterised by projections on the base unit, which extend upwards in the assembly position and have stop faces for abutment against counterfaces of the supporting elements, in each case on the side of the supporting elements facing towards the angle guide element (30; 30a, 30b). - two angle guide elements (30; 30a, 30b) which are disposed on both sides of the rail foot; - one supporting element on the side of each angle guide element (30; 30a, 30b) facing away from the rail foot; - two screw bolts for tightening rail clamps which are disposed so as to extend through openings in the angle guide plates (30; 30a, 30b) in the assembled state; and - a base unit which is disposed under the angle guide elements (30; 30a, 30b) and supporting elements of the fixing point;
A vehicle for transporting one or more substantially cylindrical items, wherein each cylindrical item has a cylindrical axis and a cylindrical surface, said vehicle comprising: a support (110, 120, 130) for supporting one or more of the cylindrical items; one or more skate guides for guiding one or more skates, wherein the one or more skate guides each have a longitudinal axis that is substantially parallel to the cylindrical axis of the cylindrical item supported by the support (110, 120, 130); characterised in that said vehicle comprises one or more skates, the or each skate being insertable and retractable along one of the skate guides and having a first, raised, configuration arranged to support the cylindrical item about its cylindrical axis during insertion or retraction of the skate and a second, lowered, configuration arranged to disconnect the skate from the cylindrical item for insertion or retraction of the skate alone, the or each skate being completely retractable from the vehicle; wherein, one or more bearing means comprising roller ball casters for receiving a side thrust from one or more skates during insertion or retraction along one of the skate guides is provided. a support (110, 120, 130) for supporting one or more of the cylindrical items; one or more skate guides for guiding one or more skates, wherein the one or more skate guides each have a longitudinal axis that is substantially parallel to the cylindrical axis of the cylindrical item supported by the support (110, 120, 130);