mhurhangee/ep-ind-claims huggingface dataset:
A combination comprising: a motor vehicle having a frame assembly; a pair of lost motion connecting structures each having a first mounting portion and a second mounting portion movably mounted to one another, the second mounting portions being connected to spaced lateral portions of the vehicle frame assembly; and a bumper beam operatively connected to the first mounting portions of the lost motion connecting structures, wherein the lost motion connecting structures are constructed and arranged such that during an offset collision proximate one of the lost motion connecting structures the first mounting portion of the other lost motion connecting structure moves relative to the second mounting portion to permit the portion of the bumper associated therewith to move relatively away from the frame assembly, wherein each lost motion connecting structure includes a hinge plate assembly having a first mounting plate and a second mounting plate pivotally connected by a hinge, one of the first and second mounting plates (51, 53) being connected to the spaced lateral portions of the vehicle frame assembly and the other of the first and second mounting plates being connected to the bumper beam, wherein the hinge plate assembly is movable from a closed position in which the first and second mounting plates (51, 53) are adjacent one another to an open position in which the first and second mounting plates (51, 53) are pivoted relative to one another during the offset collision. a motor vehicle having a frame assembly; a pair of lost motion connecting structures each having a first mounting portion and a second mounting portion movably mounted to one another, the second mounting portions being connected to spaced lateral portions of the vehicle frame assembly; and a bumper beam operatively connected to the first mounting portions of the lost motion connecting structures, wherein the lost motion connecting structures are constructed and arranged such that during an offset collision proximate one of the lost motion connecting structures the first mounting portion of the other lost motion connecting structure moves relative to the second mounting portion to permit the portion of the bumper associated therewith to move relatively away from the frame assembly, wherein each lost motion connecting structure includes a hinge plate assembly having a first mounting plate and a second mounting plate pivotally connected by a hinge, one of the first and second mounting plates (51, 53) being connected to the spaced lateral portions of the vehicle frame assembly and the other of the first and second mounting plates being connected to the bumper beam, wherein the hinge plate assembly is movable from a closed position in which the first and second mounting plates (51, 53) are adjacent one another to an open position in which the first and second mounting plates (51, 53) are pivoted relative to one another during the offset collision.
Method for visible-light communication between equipment comprising data processing means and a light emitting diode and a mobile terminal comprising data processing means, optical acquisition means and a flash, the method being characterised in that it comprises the implementation of steps of: (a) emission by the light emitting diode of at least one first light signal representing a first data item; (b) acquisition of said first light signal by the optical acquisition means, and reconstitution attempt to reconstitute said first data item by the data processing means of the mobile terminal; (c) generation by the data processing means of the mobile terminal of a second data item according to the result of the reconstitution of the first data item; (d) emission by the flash of a second light signal representing the second data item; (e) detection by the data processing means of the equipment of a reverse current produced by the light emitting diode due to said second light signal; the method comprising the periodic implementation of a cycle of charging the light emitting diode, discharging the light emitting diode during a predetermined period, measuring the voltage at the terminals of the light emitting diode, and comparing with a threshold; so as to detect said reverse current, said cycle having a variable period, the method comprising the selection of an operating mode between an active mode in which the cycle has a first period T1 allowing acquisition of a light signal, and at least one standby mode wherein the cycle has a second period T0 substantially greater than the first period. (a) emission by the light emitting diode of at least one first light signal representing a first data item; (b) acquisition of said first light signal by the optical acquisition means, and reconstitution attempt to reconstitute said first data item by the data processing means of the mobile terminal; (c) generation by the data processing means of the mobile terminal of a second data item according to the result of the reconstitution of the first data item; (d) emission by the flash of a second light signal representing the second data item; (e) detection by the data processing means of the equipment of a reverse current produced by the light emitting diode due to said second light signal; the method comprising the periodic implementation of a cycle of charging the light emitting diode, discharging the light emitting diode during a predetermined period, measuring the voltage at the terminals of the light emitting diode, and comparing with a threshold; so as to detect said reverse current, said cycle having a variable period, the method comprising the selection of an operating mode between an active mode in which the cycle has a first period T1 allowing acquisition of a light signal, and at least one standby mode wherein the cycle has a second period T0 substantially greater than the first period.
A device for separating a plurality of molecular analytes according to both isoelectric points and electrophoretic mobility within one dimension, the device comprising a chamber for containing a solution having a plurality of molecular analytes, wherein the chamber contains a sieving medium suitable for electrophoresis; an electrical source for applying an electric field along an axis in the chamber; a one or more ion sources for establishing a pH gradient along said axis in said chamber by injecting ion flows, capable of forming one or more pH steps in a pH gradient, wherein each of said ion sources is a proton injector or a hydroxide injector separated from said chamber by a bipolar membrane; and a controller which operates said one or more ion sources to adjust the pH gradient so as to induce migration and capturing of the molecular analytes separately along the axis.
A switch that is provided with a plunger configured to linearly move from a reference position to an operation position in response to an operation performed on an operation portion, and that is configured to open and close contacts according to the movement of the plunger, the switch comprising: a torsion spring (45a, 45b) configured to bias the plunger in a returning direction from the operation position to the reference position, wherein the torsion spring (45a, 45b) has an arm that extends to the plunger and abuts against the plunger, the plunger has a hole at a position into which the arm is inserted, and the hole is a through hole extending in a direction that is perpendicular to a direction in which the plunger moves, and is the same as a direction in which the arm extends when viewed in the direction in which the plunger moves characterized in that, the torsion spring (45a, 45b) has a sliding member in a front end portion of the arm, and the sliding member of the torsion spring (45a, 45b) abuts against the plunger in the reference position. a torsion spring (45a, 45b) configured to bias the plunger in a returning direction from the operation position to the reference position, wherein the torsion spring (45a, 45b) has an arm that extends to the plunger and abuts against the plunger, the plunger has a hole at a position into which the arm is inserted, and the hole is a through hole extending in a direction that is perpendicular to a direction in which the plunger moves, and is the same as a direction in which the arm extends when viewed in the direction in which the plunger moves characterized in that, the torsion spring (45a, 45b) has a sliding member in a front end portion of the arm, and the sliding member of the torsion spring (45a, 45b) abuts against the plunger in the reference position.
A polymeric material for use in thermal insulation, wherein the polymeric material is formed from a thermoplastic composition containing a continuous phase that includes a matrix polymer, and further wherein a polymeric microinclusion additive and a polymeric nanoinclusion additive are dispersed within the continuous phase in the form of discrete domains, wherein a porous network is defined in the material that includes a plurality of nanopores having an average cross-sectional dimension of 800 nanometers or less, wherein the polymeric material exhibits a thermal conductivity of 0.20 watts per meter-kelvin or less; wherein the micro-scale domains have an average cross-sectional dimension of from 0.5 to 250 micrometers; wherein the nano-scale domains have an average cross-sectional dimension of from 1 nanometer to 500 nanometers; wherein the microinclusion additive constitutes from 0.1 wt.% to 30 wt.% of the composition; and wherein the nanoinclusion additive constitutes from 0.01 wt.% to 15 wt.% of the composition.
A recombinant adenovirus genome, comprising a heterologous open reading frame and a self-cleaving peptide coding sequence, both operably linked to and in the same reading frame as an endogenous adenovirus ORF, wherein the self-cleaving peptide coding sequence is located between the heterologous ORF and the endogenous ORF, and wherein: the endogenous ORF is E1B-55k and the heterologous ORF is 3' of E1B-55k; the endogenous ORF is DNA polymerase and the heterologous ORF is 5' of DNA polymerase; the endogenous ORF is DNA-binding protein and the heterologous ORF is 3' of DBP; the endogenous ORF is adenovirus death protein and the heterologous ORF is 5' of ADP; the endogenous ORF is E3-14.7k and the heterologous ORF is 3' of E3-14.7k; or the endogenous ORF is E4-ORF2 and the heterologous ORF is 5' of E4-ORF2. the endogenous ORF is E1B-55k and the heterologous ORF is 3' of E1B-55k; the endogenous ORF is DNA polymerase and the heterologous ORF is 5' of DNA polymerase; the endogenous ORF is DNA-binding protein and the heterologous ORF is 3' of DBP; the endogenous ORF is adenovirus death protein and the heterologous ORF is 5' of ADP; the endogenous ORF is E3-14.7k and the heterologous ORF is 3' of E3-14.7k; or the endogenous ORF is E4-ORF2 and the heterologous ORF is 5' of E4-ORF2.
A downhole flow tool, comprising: a housing having a bore and defining first and second ports (118, 112) communicating the bore outside the housing; a first insert disposed in the bore and movable from a first position to a second position; and a second insert movably disposed in the bore relative to the second port, the second insert having a catch (146, 148) for moving the second insert; characterized in that the first insert conceals the catch (146, 148) when the first insert has the first position such that the catch (146, 148) has an inactive condition; control circuitry (130, 160) opens fluid communication through the first port in response to a predetermined signal; the first insert moves from the first position to the second position in response to fluid pressure from the first port, the first insert revealing the catch (146, 148) when the first insert moves toward the second position such that the catch (146, 148) has the active condition for moving the second insert; and the second insert moves from a closed condition restricting fluid communication through the second port to an opened condition permitting fluid communication through the second port when the revealed catch is engaged. a housing having a bore and defining first and second ports (118, 112) communicating the bore outside the housing; a first insert disposed in the bore and movable from a first position to a second position; and a second insert movably disposed in the bore relative to the second port, the second insert having a catch (146, 148) for moving the second insert; characterized in that the first insert conceals the catch (146, 148) when the first insert has the first position such that the catch (146, 148) has an inactive condition; control circuitry (130, 160) opens fluid communication through the first port in response to a predetermined signal; the first insert moves from the first position to the second position in response to fluid pressure from the first port, the first insert revealing the catch (146, 148) when the first insert moves toward the second position such that the catch (146, 148) has the active condition for moving the second insert; and the second insert moves from a closed condition restricting fluid communication through the second port to an opened condition permitting fluid communication through the second port when the revealed catch is engaged.
A vial adaptor configured to couple with a vial, the vial adaptor comprising: a piercing member configured to be introduced into the vial through a septum of the vial; an extractor channel, wherein fluid withdrawn from the vial flows through the extractor channel; a reservoir comprising sterilized gas, wherein the reservoir is housed in a casing member; and a regulator channel configured to releasably contain the sterilized gas within the reservoir and fluidly connect the reservoir to the vial when the vial adaptor is coupled with the vial; wherein, as fluid is withdrawn from the vial through the extractor channel, the vial adaptor is configured to permit the sterilized gas to pass through the regulator channel, and into the vial. a piercing member configured to be introduced into the vial through a septum of the vial; an extractor channel, wherein fluid withdrawn from the vial flows through the extractor channel; a reservoir comprising sterilized gas, wherein the reservoir is housed in a casing member; and a regulator channel configured to releasably contain the sterilized gas within the reservoir and fluidly connect the reservoir to the vial when the vial adaptor is coupled with the vial; wherein, as fluid is withdrawn from the vial through the extractor channel, the vial adaptor is configured to permit the sterilized gas to pass through the regulator channel, and into the vial.
An antibody drug conjugate composed of an antibody or antibody fragment, tridentate linker, linker and drug of the general scheme wherein said ADC is of formula V, VI, VII or VIII: wherein D is a drug part; wherein C is a cleavable linker; E is a self immolative linker, F is an optional self immolative linker; e or f is an integer of 0-5; G is a noncleavable linker; g is an integer of 0-5; n' is an integer of 1-8; and wherein L' and L are part of the same antibody or antibody fragment; Z is O, S, NR 2, C(=O)O, C(=O)NR 3, C(=S)O, C(=S)NR 4, C(=S)S, NR 5 C(=O)NR 6, NR 7 C(=S)NR 8, or OC(=O)NR 9; wherein m is 0 or 1; R 1 is linear alkyl, cycloalkyl, heterocyclyalkyl, alkenyl, alkynyl, aryl, heteroaryl, poly(ethylene glycol) chain, or any combination thereof; n is an integer of 0-8; R 2, R 3, R 4, R 5, R 6, R 7, R 8, and R 9 are independently selected from H, linear alkyl, cycloalkyl, heterocycloalkyl, alkenyl, alkynyl, aryl, heteroaryl; X is -NR 10 -, -O-, -S-, -C(=O)-, -C(=S)-, -NR 11 C(=O)-, -NR 12 C(=S)-, -OC(=O)-, or -OC(=S)-; wherein R 10, R 11, and R 12 are independently selected from H, linear alkyl, cycloalkyl, heterocycloalkyl, alkenyl, alkynyl, aryl, heteroaryl; J is a substitution group, including H, halogen, nitro, cyano, hydroxyl, alkoxy, amino, amide, ester, sulfamide, urea, linear alkyl, cycloalkyl, heterocycloalkyl, alkenyl, alkynyl, aryl, heteroaryl; o is 0, 1, 2 or 3; R 13, R 14, R 15 and R 16 are independently selected from linear alkyl, cycloalkyl, heterocycloalkyl, alkenyl, alkynyl, aryl, heteroaryl, or any combination thereof; Q is N or CR 17; R 17 is independently selected from H, linear alkyl, cycloalkyl, heterocycloalkyl, alkenyl, alkynyl, aryl, and heteroaryl; p, q is an integer of 0-8; x, y is an integer of 0-8, and x + y ≥ 1.
A conveyor assembly configured to move material relative to a mine face, the conveyor assembly comprising: a conveyor pan configured to support the material; a drive unit including a drive shaft and a plurality of sprockets secured to the drive shaft, the drive shaft driven about a rotational axis; and a conveying element including a plurality of chains and a plurality of flights, each of the chains driven by one of the sprockets to move the chain and the flights over the conveyor pan, each of the flights coupled between the plurality of chains, each of the plurality of flights including a first portion and a second portion, the first portion coupled to the second portion by a movable joint (210, 222), the flights configured to move the material over the conveyor pan, wherein the plurality of sprockets are angularly offset about the rotational axis relative to each other, and wherein the first portion moves relative to the second portion at the movable joint (210, 222) in response to the plurality of chains engaging the plurality of sprockets and moving about the rotational axis. a conveyor pan configured to support the material; a drive unit including a drive shaft and a plurality of sprockets secured to the drive shaft, the drive shaft driven about a rotational axis; and a conveying element including a plurality of chains and a plurality of flights, each of the chains driven by one of the sprockets to move the chain and the flights over the conveyor pan, each of the flights coupled between the plurality of chains, each of the plurality of flights including a first portion and a second portion, the first portion coupled to the second portion by a movable joint (210, 222), the flights configured to move the material over the conveyor pan, wherein the plurality of sprockets are angularly offset about the rotational axis relative to each other, and wherein the first portion moves relative to the second portion at the movable joint (210, 222) in response to the plurality of chains engaging the plurality of sprockets and moving about the rotational axis.
A cable drum feeding tool for a vehicle with a lifting device, the tool comprises - a primary gripper arm arrangement comprising a primary first gripper arm and a primary second gripper arm extending parallel and spaced apart from each other by means of a spacing, and a connection element connecting the primary first gripper arm and the primary second gripper arm, - a primary gripper arm mechanism for moving at least one of the primary first gripper arm and the primary second gripper arm towards and away from the other of the primary gripper arms (12, 14), - a rotation mechanism comprising a respective pivot (32, 34) at the primary first gripper arm and the primary second gripper arm adapted to engage with respective flanges of a cable drum, and the tool comprises an attachment arrangement for releasably attaching the tool to said lifting device of the vehicle, wherein the pivots (32, 34) comprise a respective conical member adapted to engage with a wall section of an opening in the flange of the cable drum and a respective plate member adapted to engage with the flanges of the cable drum, wherein the pivots (32, 34) further comprise a connection mechanism for moving the plate member between a disengaged position and an engaged position with the flange of the drum, wherein the connection mechanism comprises a movable connection member adapted to be contacted by the conical member and transfer a force to the plate member that moves the plate member from the disengaged position and the engaged position, characterised in that the connection member comprises two or more connection arms comprising a first end portion adapted to be contacted by the conical member and a second end portion adapted to contact the plate member for transferring said force to the plate member. - a primary gripper arm arrangement comprising a primary first gripper arm and a primary second gripper arm extending parallel and spaced apart from each other by means of a spacing, and a connection element connecting the primary first gripper arm and the primary second gripper arm, - a primary gripper arm mechanism for moving at least one of the primary first gripper arm and the primary second gripper arm towards and away from the other of the primary gripper arms (12, 14), - a rotation mechanism comprising a respective pivot (32, 34) at the primary first gripper arm and the primary second gripper arm adapted to engage with respective flanges of a cable drum, and
A method for in vitro diagnosis or prognosis of testicular cancer, in a testicular sample, from a patient suspected of suffering from testicular cancer, characterized in that it comprises a step of detecting the presence or absence of at least one expression product from at least one nucleic acid sequence selected from the sequences identified in SEQ ID Nos.: 1 to 6 or from the sequences which exhibit at least 99% identity with one of the sequences identified in SEQ ID Nos.: 1 to 6, a step of comparing the quantity of the expression product of the sample to be analyzed, compared with the quantity of the expression product of an healthy sample; in which an overexpression in the analyzed sample, compared with the expression in the healthy sample, is correlated to the testicular cancer.
A medical device having stability and alignability along an axis of one or more of finger, hand, and arm of user, thereby allowing a user to accurately orient an operable end without a need of direct visualization, the medical device comprising: a flexible tubular member having a lumen extending from a proximal end to a distal end, a connection mechanism having a tapered ridge on a distal end portion of the flexible tubular member, wherein the lumen of the flexible tubular member is configured to receive an actuator; a finger sheath unit coupled to a distal portion of the flexible tubular member along a central axis of the flexible tubular member with a receiver where the receiver is configured to receive the tapered ridge of the connection mechanism, wherein the finger sheath unit comprises a first finger sheath and a second finger sheath arranged substantially in a similar plane; and a suture or an anchor; an operational unit releasably coupled to the distal portion of the flexible tubular member with a connection mechanism, wherein the operational unit is configured to deliver, one of the suture or the anchor, wherein the operational unit is arranged below the finger sheath unit; and an actuator configured to fit within a portion of the lumen of the flexible tubular member and actuate the operational unit upon movement of the actuator from a first location to second location. a flexible tubular member having a lumen extending from a proximal end to a distal end, a connection mechanism having a tapered ridge on a distal end portion of the flexible tubular member, wherein the lumen of the flexible tubular member is configured to receive an actuator; a finger sheath unit coupled to a distal portion of the flexible tubular member along a central axis of the flexible tubular member with a receiver where the receiver is configured to receive the tapered ridge of the connection mechanism, wherein the finger sheath unit comprises a first finger sheath and a second finger sheath arranged substantially in a similar plane; and a suture or an anchor; an operational unit releasably coupled to the distal portion of the flexible tubular member with a connection mechanism, wherein the operational unit is configured to deliver, one of the suture or the anchor, wherein the operational unit is arranged below the finger sheath unit; and an actuator configured to fit within a portion of the lumen of the flexible tubular member and actuate the operational unit upon movement of the actuator from a first location to second location.