mhurhangee/ep-ind-claims huggingface dataset:
A method for controlling charging of a rechargeable power source of an implantable medical device in a patient, the method comprising: determining, by a processor, an estimated power stored in the rechargeable power source during charging of the rechargeable power source, the estimated power stored being separate from a resistive heat loss (302, 304) of the rechargeable power source during charging of the rechargeable power source; calculating, by the processor, an estimated energy transfer to tissue of the patient during charging of the rechargeable power source, the estimated energy transfer including the resistive heat loss of the rechargeable power source; and controlling, by the processor and based on the estimated energy transfer to the tissue, energy generation by a primary coil of an external charging device for charging the rechargeable power source via a secondary coil of the implantable medical device. determining, by a processor, an estimated power stored in the rechargeable power source during charging of the rechargeable power source, the estimated power stored being separate from a resistive heat loss (302, 304) of the rechargeable power source during charging of the rechargeable power source; calculating, by the processor, an estimated energy transfer to tissue of the patient during charging of the rechargeable power source, the estimated energy transfer including the resistive heat loss of the rechargeable power source; and controlling, by the processor and based on the estimated energy transfer to the tissue, energy generation by a primary coil of an external charging device for charging the rechargeable power source via a secondary coil of the implantable medical device.
A composition for use in tissue engineering comprising: a supporting scaffold for growing isolated differentiable human mesenchymal stem cells, the supporting scaffold comprising an electrospun three-dimensional matrix of a non-woven mesh of nanofibers formed by electrospinning a solution of poly-D,L-lactide glycolide (PLGA), the matrix being seeded initially with isolated differentiable human mesenchymal stem cells having a CD44+, CD34-, CD45- phenotype, wherein the differentiable human mesenchymal stem cells have differentiated into a mature osteoblast cell phenotype or a mature chondrocyte cell phenotype on the scaffold. a supporting scaffold for growing isolated differentiable human mesenchymal stem cells, the supporting scaffold comprising an electrospun three-dimensional matrix of a non-woven mesh of nanofibers formed by electrospinning a solution of poly-D,L-lactide glycolide (PLGA), the matrix being seeded initially with isolated differentiable human mesenchymal stem cells having a CD44+, CD34-, CD45- phenotype, wherein the differentiable human mesenchymal stem cells have differentiated into a mature osteoblast cell phenotype or a mature chondrocyte cell phenotype on the scaffold.
A metering device for metering a material, in particular a material to be dried such as a fermentation substrate or manure, comprising a conveying device for conveying material to be dried in a conveying direction, wherein material to be dried may be fed onto the conveying device by a feed means and wherein the conveying device may discharge material to be dried to a downstream unit, such as for example a drying device, and a control unit, which is configured to control a conveying velocity of the conveying device, wherein the conveying device is arranged so as to be pivotable about a vertical pivot axis, characterised in that the control unit is arranged and configured to control an oscillating motion, preferably a velocity, in particular an angular velocity, and/or a frequency of the oscillating motion, of the conveying device about the pivot axis, characterised in that the control unit is configured to control the velocity of the oscillating motion of the conveying device in such a way that the velocity of the oscillating motion of the conveying device is greater in the region of the reversal points (P 1, P 2, P 3, P 4, P 5) of a trajectory of the oscillating motion than between the reversal points (P 1, P 2, P 3, P 4, P 5).
An electromagnetic-clutch rotation stopping structure for stopping the rotation of an electromagnetic clutch of a phase varying apparatus equipped with: a sprocket (36, 37) and a brake drum (34, 54) coaxially supported by the camshaft for relative rotation thereto and driven by the crankshaft of an automobile engine; an electromagnetic clutch cover having a clutch holding section (71, 72) formed in the circumferential surface thereof coaxially with the camshaft; and a cylindrical electromagnetic clutch (35, 56) that is coaxial with the brake drum (34, 54) and adapted to put a brake on the brake drum (34, 54) as needed to change the phase angle between the camshaft and the crankshaft when stopped by the electromagnetic clutch cover unrotatable relative to the electromagnetic clutch cover, the electromagnetic-clutch rotation stopping structure is characterized by comprising: a substantially C-shaped leaf spring (73, 74) for holding the electromagnetic clutch in the same radial plane as the leaf spring mounted on the circumferential surface of the clutch holding section; first rotation stopping means (71e, 72d, 73a, 74a) provided between the electromagnetic clutch holding section and leaf spring; and second rotation stopping means (35d, 56b, 73b, 74b) provided between the leaf spring and electromagnetic clutch. a substantially C-shaped leaf spring (73, 74) for holding the electromagnetic clutch in the same radial plane as the leaf spring mounted on the circumferential surface of the clutch holding section; first rotation stopping means (71e, 72d, 73a, 74a) provided between the electromagnetic clutch holding section and leaf spring; and second rotation stopping means (35d, 56b, 73b, 74b) provided between the leaf spring and electromagnetic clutch.
A cutting block comprising a mounting surface in which the mounting surface defines a first pair of openings for receiving a mounting projection installed in a bone; wherein the mounting surface further defines a first blind recess, a blind recess being a recess that does not extend through the entire depth of the surgical instrument and which extends linearly from each opening; in which the cutting block comprises a first side adjacent the mounting surface and a second side adjacent the mounting surface and opposite to the first side surface characterised in that the cutting block further includes a second pair of openings for receiving a mounting projection installed in a bone, and the mounting surface further defines a second blind recess in which each of the first and second blind recesses extends across the entirety of the mounting surface from a first edge of the mounting surface to a second edge of the mounting surface such that the first blind recess extends past the first pair of openings and into both the first and second side surfaces, and the second blind recess extends past the second pair of openings and into both the first and second side surfaces.
A system for executing one or more functions on a vehicle computing system, the system comprising: at least one vehicle computing system configured to: receive input associating one or more functions in a vehicle with at least one of one or more contacts or one or more other vehicle functions in order to select the one or more vehicle functions for execution; associate the one or more vehicle functions with at least one of the one or more contacts or the one or more other vehicle functions based on the input; display the one or more vehicle functions which are associated with the one or more contacts or with the one or more other vehicle functions; receive a selection of the one or more vehicle functions which are associated with at least one of the one or more contacts or the one or more other vehicle functions; execute the one or more vehicle functions in response to the selection while an application associated with the one or more contacts or the one or more other vehicle functions is running on the at least one vehicle computing system; and upon execution of the one or more vehicle functions, display the one or more contacts or the one or more other vehicle functions associated with the executing vehicle function. receive input associating one or more functions in a vehicle with at least one of one or more contacts or one or more other vehicle functions in order to select the one or more vehicle functions for execution; associate the one or more vehicle functions with at least one of the one or more contacts or the one or more other vehicle functions based on the input; display the one or more vehicle functions which are associated with the one or more contacts or with the one or more other vehicle functions; receive a selection of the one or more vehicle functions which are associated with at least one of the one or more contacts or the one or more other vehicle functions; execute the one or more vehicle functions in response to the selection while an application associated with the one or more contacts or the one or more other vehicle functions is running on the at least one vehicle computing system; and upon execution of the one or more vehicle functions, display the one or more contacts or the one or more other vehicle functions associated with the executing vehicle function.
A last for forming a footwear upper configuring an article of footwear, comprising a heel portion, a front foot portion and a middle foot portion, wherein the last further comprises: a foot length forming member that defines a shape of the last at least in a lengthwise direction of the article of footwear; a plurality of foot width forming members that define a shape of the last at least in a widthwise direction of the article of footwear and are assembled to the foot length forming member; wherein the plurality of the foot width forming members are aligned in a heightwise direction in the heel portion of the last and aligned in the lengthwise direction in the front foot portion and the middle foot portion of the last, wherein in the heel portion of the last the foot length forming member has formed therein a plurality of engagement grooves aligned at equal intervals in the heightwise direction, wherein the plurality of foot width forming members are assembled in engagement grooves and thus aligned at equal intervals in the heightwise direction. a foot length forming member that defines a shape of the last at least in a lengthwise direction of the article of footwear; a plurality of foot width forming members that define a shape of the last at least in a widthwise direction of the article of footwear and are assembled to the foot length forming member; wherein the plurality of the foot width forming members are aligned in a heightwise direction in the heel portion of the last and aligned in the lengthwise direction in the front foot portion and the middle foot portion of the last, wherein in the heel portion of the last the foot length forming member has formed therein a plurality of engagement grooves aligned at equal intervals in the heightwise direction, wherein the plurality of foot width forming members are assembled in engagement grooves and thus aligned at equal intervals in the heightwise direction.
An oral anticancer vaccine composition comprising spray-dried microparticles comprising β-cyclodextrin, hydroxypropylmethyl cellulose acetate succinate (HPMCAS), ethyl cellulose, recombinant SP17 protein, aleuria aurantia lectin in a microfold cell (M-cell) targeting effective amount and CpG in an innate immune response stimulatory amount, the β-cyclodextrin, hydroxypropylmethyl cellulose acetate succinate (HPMCAS) and ethyl cellulose comprised in a gastric acid resistant, enteric erodable matrix, and the recombinant SP17 protein being encapsulated in the particles and provided in an amount within the range from 1 to 10% w/w based on the weight of the particles. the β-cyclodextrin, hydroxypropylmethyl cellulose acetate succinate (HPMCAS) and ethyl cellulose comprised in a gastric acid resistant, enteric erodable matrix, and the recombinant SP17 protein being encapsulated in the particles and provided in an amount within the range from 1 to 10% w/w based on the weight of the particles.
Method for operating a transmission device for a motor vehicle, wherein a driving gear is selected from a set of driving gears (6,7) and set on a transmission and, on exceeding an upper speed limit, a gear with a larger gear ratio is selected from the set of driving gears (6,7) and set on the transmission, wherein in a normal operating mode, the set of driving gears (6,7) corresponds to a normal operation set of driving gears, which comprises a plurality of different driving gears, and the upper speed limit corresponds to a normal operation upper speed limit, and in an alternative operating mode, the set of driving gears (6,7) corresponds to and alternative operation set of driving gears, which has a smaller number of different driving gears than the normal operation set of driving gears, and the upper speed limit corresponds to an alternative operation upper speed limit that is different from the normal operation upper speed limit, characterised in that a smallest driving gear of the alternative operation set of driving gears is larger than the smallest driving gear of the normal operation set of driving gears, and that the alternative operation upper speed limit is higher than the normal operation upper speed limit.
An occupancy sensing unit configured to monitor an environment illuminated by a lighting fixture, the occupancy sensing unit comprising: A) at least one occupancy sensor to detect radiation indicative of at least one occupancy event, in the environment illuminated by the lighting fixture, according to sensing parameters; B) a memory coupled to the at least one occupancy sensor; characterised in that the memory is configured to log sensor data, representing a velocity and/or a trajectory associated with the at least one occupancy event, provided by the at least one occupancy sensor; and in that said occupancy sensing unit further comprising C) a processor coupled to the memory and configured to: C1) perform an analysis of the sensor data logged in the memory, the analysis comprising determining a frequency with which a particular velocity and/or a particular trajectory appears in the sensor data, and C2) adjust the sensing parameters of the at least one occupancy sensor based on the analysis of the sensor data logged in the memory. A) at least one occupancy sensor to detect radiation indicative of at least one occupancy event, in the environment illuminated by the lighting fixture, according to sensing parameters; B) a memory coupled to the at least one occupancy sensor; characterised in that the memory is configured to log sensor data, representing a velocity and/or a trajectory associated with the at least one occupancy event, provided by the at least one occupancy sensor; and in that said occupancy sensing unit further comprising C) a processor coupled to the memory and configured to: C1) perform an analysis of the sensor data logged in the memory, the analysis comprising determining a frequency with which a particular velocity and/or a particular trajectory appears in the sensor data, and C2) adjust the sensing parameters of the at least one occupancy sensor based on the analysis of the sensor data logged in the memory. C1) perform an analysis of the sensor data logged in the memory, the analysis comprising determining a frequency with which a particular velocity and/or a particular trajectory appears in the sensor data, and C2) adjust the sensing parameters of the at least one occupancy sensor based on the analysis of the sensor data logged in the memory.
A system for treating target tissue, the system comprising: an ablation device comprising: a first elongate tube with a proximal portion, a distal portion, and a first lumen extending from the proximal portion to the distal portion; and an expandable treatment element mounted to the first elongate tube and in fluid communication with the first lumen; and an energy delivery unit constructed and arranged to deliver energy to the expandable treatment element; and a second elongate tube with a second lumen and a port configured to extract fluid delivered by the first elongate tube; wherein the system is constructed and arranged to deliver a thermal dose of energy, sufficient to effect ablation, to the target tissue, wherein delivering the thermal dose comprises delivering a continuous flow of fluid to and from the treatment element; and wherein the expandable treatment element comprises a balloon, characterized in that the device is configured to thermally prime, prior to delivery of the thermal dose of energy, by delivering fluid at an elevated temperature while preventing pressure within the expandable treatment element from exceeding a pressure threshold for inflation. a first elongate tube with a proximal portion, a distal portion, and a first lumen extending from the proximal portion to the distal portion; and an expandable treatment element mounted to the first elongate tube and in fluid communication with the first lumen; and an energy delivery unit constructed and arranged to deliver energy to the expandable treatment element; and a second elongate tube with a second lumen and a port configured to extract fluid delivered by the first elongate tube; wherein the system is constructed and arranged to deliver a thermal dose of energy, sufficient to effect ablation, to the target tissue, wherein delivering the thermal dose comprises delivering a continuous flow of fluid to and from the treatment element; and wherein the expandable treatment element comprises a balloon, characterized in that the device is configured to thermally prime, prior to delivery of the thermal dose of energy, by delivering fluid at an elevated temperature while preventing pressure within the expandable treatment element from exceeding a pressure threshold for inflation.
A reciprocating compressor, comprising: a piston reciprocatably disposed in compression cylinder; a translatable assembly connected to the piston; an electromagnetic drive having a fixed stator and a core coupled to the translatable assembly, the drive configured to reciprocatably drive the translatable assembly; and an accumulator coupled to the translatable assembly, wherein the accumulator is configured to store kinetic energy resident in the motion of a movement of the translatable assembly in a first direction, and wherein the accumulator is configured to impart kinetic energy resident in the motion of a movement of the translatable assembly in a second direction; and characterised in that the accumulator comprises: a connecting rod defining a first movable flange and a second movable flange, a fixed post having an aperture to slidably receive the connecting rod therein; a first resilient member disposed between the first movable flange and the fixed post; and a second resilient member disposed between the second movable flange and the fixed post. a piston reciprocatably disposed in compression cylinder; a translatable assembly connected to the piston; an electromagnetic drive having a fixed stator and a core coupled to the translatable assembly, the drive configured to reciprocatably drive the translatable assembly; and an accumulator coupled to the translatable assembly, wherein the accumulator is configured to store kinetic energy resident in the motion of a movement of the translatable assembly in a first direction, and wherein the accumulator is configured to impart kinetic energy resident in the motion of a movement of the translatable assembly in a second direction; and characterised in that the accumulator comprises: a connecting rod defining a first movable flange and a second movable flange, a fixed post having an aperture to slidably receive the connecting rod therein; a first resilient member disposed between the first movable flange and the fixed post; and a second resilient member disposed between the second movable flange and the fixed post. a connecting rod defining a first movable flange and a second movable flange, a fixed post having an aperture to slidably receive the connecting rod therein; a first resilient member disposed between the first movable flange and the fixed post; and a second resilient member disposed between the second movable flange and the fixed post.
An immediate release pharmaceutical composition comprising 0.10 % to 3.00 % (wt/wt) of pomalidomide; 40.00 % to 93.00 % (wt/wt) of anhydrous lactose as a diluent; 6.00 % to 25.00 % (wt/wt) of hypromellose as a binder. 0.10 % to 3.00 % (wt/wt) of pomalidomide; 40.00 % to 93.00 % (wt/wt) of anhydrous lactose as a diluent; 6.00 % to 25.00 % (wt/wt) of hypromellose as a binder.
A method for forming a glass-containing microfluidic device having at least one fluid passage therethrough, the method comprising: providing a first piece (3; 62; 82) having a patterned molding surface; providing a first amount of glass-containing composition (2; 60; 81); contacting the first amount of glass-containing composition (2; 60; 81) with the patterned molding surface; pressing the first amount of glass-containing composition (2; 60; 81) between the patterned molding surface and a second surface; heating the first piece (3; 62; 82) and the first amount of glass-containing composition (2; 60; 81) together sufficiently to soften the amount of glass-containing composition (2; 60; 81) such that the patterned molding surface is replicated in the first amount of glass-containing composition (2; 60; 81), the first amount of glass-containing composition (2; 60; 81) forming a first formed glass-containing article (51; 63; 91); sealing at least a portion of the first formed glass-containing article (51; 63; 91) to create a microfluidic device having at least one fluidic passage therethrough; characterized in that said first piece (3; 62; 82) is of a rigid, non-stick material, in that the step of heating together comprises heating to a temperature sufficient to produce molten glass and result in viscous flow of the glass-containing composition (2; 60; 81) and in that the second surface comprises a surface of a substrate onto which the glass-containing composition is to be formed, said heating step being effective to attach or join the glass-containing composition to the surface of the substrate. providing a first piece (3; 62; 82) having a patterned molding surface; providing a first amount of glass-containing composition (2; 60; 81); contacting the first amount of glass-containing composition (2; 60; 81) with the patterned molding surface; pressing the first amount of glass-containing composition (2; 60; 81) between the patterned molding surface and a second surface; heating the first piece (3; 62; 82) and the first amount of glass-containing composition (2; 60; 81) together sufficiently to soften the amount of glass-containing composition (2; 60; 81) such that the patterned molding surface is replicated in the first amount of glass-containing composition (2; 60; 81), the first amount of glass-containing composition (2; 60; 81) forming a first formed glass-containing article (51; 63; 91); sealing at least a portion of the first formed glass-containing article (51; 63; 91) to create a microfluidic device having at least one fluidic passage therethrough;