mhurhangee/ep-ind-claims huggingface dataset:
A heat exchange assembly for exchanging heat between a coolant and a gaseous medium, comprising: an outer jacket; a plurality of gas tubes positioned within the outer jacket; and a self-cleaning system positioned about the plurality of gas tubes; wherein the self-cleaning system comprises a plurality of chains extending through the plurality of gas tubes. wherein the self-cleaning system comprises an upper bar attached to a first end of the plurality of chains, characterized in that the self-cleaning system comprises a lower bar attached to a second end of the plurality of chains. wherein the self-cleaning system comprises an upper bar attached to a first end of the plurality of chains, characterized in that the self-cleaning system comprises a lower bar attached to a second end of the plurality of chains.
A mechanical assembly including two rotor parts (3, 9) of a turbomachine, one of the parts being a compressor shaft, the other part being a turbine shaft, at least one of these parts having a portion with external threading, said assembly further including, for the transmission of axial forces between these two parts, a nut with internal threading able to cooperate with said external threading to axially block by tightening the other part with respect to the first part and allow the transmission of axial forces between these two parts, characterized in that the pitch of the external threading and/or the pitch of the nut varies/vary along the axial height (Ax) of the threading, the space between the thread of said external threading and the thread of the nut progressively decreasing from the first thread to the rear thread in the expected direction for the axial force, and characterized in that the pitch variation (V p) from one thread to another along the axial height of the threading is constant.
A system for providing a user device access to a resource or data, the system comprising: the user device comprising: - a light detector configured to detect light emitted by a light source, which light comprises an embedded code comprising a light source identifier of the light source, - a communication unit configured to communicate with a network device, - a processor configured to retrieve the light source identifier from the light, and to communicate the light source identifier to the network device, wherein the system further comprises the network device, comprising: - a receiver configured to receive the light source identifier from the user device, and - a controller configured to determine at which light source of a plurality of light sources the user device is present by identifying the light source based on the light source identifier, to encrypt an access key or data with a public key corresponding to a private key, and to control the identified light source such that the light comprises an updated embedded code comprising the encrypted access key or the encrypted data, wherein the processor of the user device is further configured to retrieve the encrypted access key or the encrypted data from the updated embedded code comprised in the light, and to decrypt the encrypted access key or the encrypted data with the private key, and access the resource with the decrypted access key or retrieve the decrypted data. - a light detector configured to detect light emitted by a light source, which light comprises an embedded code comprising a light source identifier of the light source, - a communication unit configured to communicate with a network device, - a processor configured to retrieve the light source identifier from the light, and to communicate the light source identifier to the network device, wherein the system further comprises the network device, comprising: - a receiver configured to receive the light source identifier from the user device, and - a controller configured to determine at which light source of a plurality of light sources the user device is present by identifying the light source based on the light source identifier, to encrypt an access key or data with a public key corresponding to a private key, and to control the identified light source such that the light comprises an updated embedded code comprising the encrypted access key or the encrypted data, - a receiver configured to receive the light source identifier from the user device, and - a controller configured to determine at which light source of a plurality of light sources the user device is present by identifying the light source based on the light source identifier, to encrypt an access key or data with a public key corresponding to a private key, and to control the identified light source such that the light comprises an updated embedded code comprising the encrypted access key or the encrypted data,
A wet type dust collecting apparatus of a vacuum cleaner, comprising: a first separating unit which filters out and discharges dust by rotating air which is inlet via a first air inlet; and a plurality of second centrifugal separating units (B') which filter out dust from the air which is discharged from the first separating unit, characterized in that the plurality of the second centrifugal separating units (B') eliminate dust from the inlet air via water which is filled inside of the second centrifugal separating units (B'). a first separating unit which filters out and discharges dust by rotating air which is inlet via a first air inlet; and a plurality of second centrifugal separating units (B') which filter out dust from the air which is discharged from the first separating unit, characterized in that the plurality of the second centrifugal separating units (B') eliminate dust from the inlet air via water which is filled inside of the second centrifugal separating units (B').
A mobile device for crushing bulky goods having at least one fibre-reinforced plastic, more particularly rotor blades for wind turbines, comprising at least one wire saw with a diamond wire, an irrigation system for releasing a fluid for cooling the diamond wire, and a collecting tank for collecting the fluid, characterised in that - a support for the bulky goods is provided in the vicinity of the diamond wire, that the support has at least one bearing element that is configured as rollers and is adjustable in height and/or inclination, and that a movable transport cart is provided which has a support for an end of the bulky goods facing away from the vicinity of the diamond wire. - a support for the bulky goods is provided in the vicinity of the diamond wire, that the support has at least one bearing element that is configured as rollers and is adjustable in height and/or inclination, and that a movable transport cart is provided which has a support for an end of the bulky goods facing away from the vicinity of the diamond wire.
A fastening system for implanting a fastener in a targeted endovascular region, the system comprising: a fastener attachment assembly sized and configured to be deployed within the targeted endovascular region and including a fastener applier that carries an actuated member that is selectively operable to generate an implantation force to implant a fastener into tissue in the targeted endovascular region; and characterised in that the system comprises a stabilizing member carried at the distal end of the fastener applier comprising an expandable basket-like structure that surrounds the fastener attachment assembly and is operable between a low profile generally collapsed profile condition, and an expanded profile condition, the expanded profile condition configured to contact a graft for applying a resolving force to resolve at least a portion of the implantation force within the targeted endovascular region, and wherein the fastener applier is maneuverable within the expanded basket-like structure into contact with the graft. a fastener attachment assembly sized and configured to be deployed within the targeted endovascular region and including a fastener applier that carries an actuated member that is selectively operable to generate an implantation force to implant a fastener into tissue in the targeted endovascular region; and characterised in that the system comprises a stabilizing member carried at the distal end of the fastener applier comprising an expandable basket-like structure that surrounds the fastener attachment assembly and is operable between a low profile generally collapsed profile condition, and an expanded profile condition, the expanded profile condition configured to contact a graft for applying a resolving force to resolve at least a portion of the implantation force within the targeted endovascular region, and wherein the fastener applier is maneuverable within the expanded basket-like structure into contact with the graft.
A device for withdrawing and applying a fluid product comprising: - a base piece mounted to a fluid product tank, the base piece comprising a dip tube defining a tube inner volume Vtp and a cup (21; 21'; 21") at the bottom of which an injection hole is formed, being connected to the dip tube, the cup being provided with a piston (27; 27') forming a piston lip having a piston diameter Dp, and - a removable member removably mounted to the base piece, the removable member comprising a gripping tab, a tubing (33'; 33"; 33) capable of sealingly sliding against the piston lip over a sealed axial stroke and an applicator capable of holding a fluid product dose from the dip tube by a suction generated by sealingly sliding the tubing (33; 33"; 33) against the piston lip over said sealed axial stroke, the applicator comprising a withdrawal and application space defining a withdrawal volume Vp, this withdrawal and application space being formed in the tubing (33; 33"; 33), the fluid product being injected into this withdrawal and application space through the dip tube and the injection hole, wherein the sealed axial stroke Cae represents an axial sliding height Hac which is determined so that this height Hac correlated with the piston diameter Dp of the piston lip defines a suction volume Va which is greater than the tube inner volume Vtp, so that Hac meets the formula: Va = Hac. π. Dp 2 / 4 > Vtp hence: Hac > 4 Vtp / π. Dp 2 characterised in that the suction volume Va is lower than the sum of the tube inner volume Vtp and of the withdrawal volume Vp, so that Hac further meets the formula: Hac < 4 Vtp + Vp / π. Dp 2 - a base piece mounted to a fluid product tank, the base piece comprising a dip tube defining a tube inner volume Vtp and a cup (21; 21'; 21") at the bottom of which an injection hole is formed, being connected to the dip tube, the cup being provided with a piston (27; 27') forming a piston lip having a piston diameter Dp, and - a removable member removably mounted to the base piece, the removable member comprising a gripping tab, a tubing (33'; 33"; 33) capable of sealingly sliding against the piston lip over a sealed axial stroke and an applicator capable of holding a fluid product dose from the dip tube by a suction generated by sealingly sliding the tubing (33; 33"; 33) against the piston lip over said sealed axial stroke, the applicator comprising a withdrawal and application space defining a withdrawal volume Vp, this withdrawal and application space being formed in the tubing (33; 33"; 33), the fluid product being injected into this withdrawal and application space through the dip tube and the injection hole, wherein the sealed axial stroke Cae represents an axial sliding height Hac which is determined so that this height Hac correlated with the piston diameter Dp of the piston lip defines a suction volume Va which is greater than the tube inner volume Vtp, so that Hac meets the formula: Va = Hac. π. Dp 2 / 4 > Vtp hence: Hac > 4 Vtp / π. Dp 2 characterised in that the suction volume Va is lower than the sum of the tube inner volume Vtp and of the withdrawal volume Vp, so that Hac further meets the formula: Hac < 4 Vtp + Vp / π. Dp 2
A vehicle display system for a vehicle, the vehicle display system comprising: a display device comprising at least one display (411, 412, 413); and at least one processor configured to: acquire sitting position data of a user in the vehicle; and provide a control signal to adjust a viewing angle of the at least one display (411, 412, 413) in accordance with the sitting position data of the user, characterized in that the at least one processor is further configured to: receive, from an internal camera of the vehicle, image data comprising a user image; detect a user's gaze and the user's finger in the image data; and based on a determination that a virtual line connecting the user's gaze and the user's finger extends to a region where the display is configured to be positioned, output content that notifies a user control availability. a display device comprising at least one display (411, 412, 413); and at least one processor configured to: acquire sitting position data of a user in the vehicle; and provide a control signal to adjust a viewing angle of the at least one display (411, 412, 413) in accordance with the sitting position data of the user, acquire sitting position data of a user in the vehicle; and provide a control signal to adjust a viewing angle of the at least one display (411, 412, 413) in accordance with the sitting position data of the user, characterized in that the at least one processor is further configured to: receive, from an internal camera of the vehicle, image data comprising a user image; detect a user's gaze and the user's finger in the image data; and based on a determination that a virtual line connecting the user's gaze and the user's finger extends to a region where the display is configured to be positioned, output content that notifies a user control availability. receive, from an internal camera of the vehicle, image data comprising a user image; detect a user's gaze and the user's finger in the image data; and
A composition comprising: an ethylene-based polymer; wherein the ethylene-based polymer comprises an ethylene plastomer/elastomer and a low density polyethylene (LDPE); a carboxylic-functionalized ethylene-based polymer; and from 0.1 wt% to 0.5 wt% of a polydimethylsiloxane, based on the total weight of the composition. an ethylene-based polymer; wherein the ethylene-based polymer comprises an ethylene plastomer/elastomer and a low density polyethylene (LDPE); a carboxylic-functionalized ethylene-based polymer; and from 0.1 wt% to 0.5 wt% of a polydimethylsiloxane, based on the total weight of the composition.
Globally activated monocytes for use in treating cancer, wherein said cancer is treated in combination with an anti-tumor therapeutic antibody, and wherein said globally activated monocytes are obtainable by a method comprising at least the steps of: a) subjecting an extracorporeal quantity of a mammalian subject's blood sample, which comprises monocytes, to a shear force such that said monocytes are globally activated, b) wherein the method is performed in the absence of photoactivatable agents such as 8-MOP, and UVA, c) wherein the method is performed without the need for addition of a molecular cocktail comprising cytokines; and d) wherein said globally activated monocytes are identified by increased expression of at least HLA-DR, PLAUR or ICAM-1. a) subjecting an extracorporeal quantity of a mammalian subject's blood sample, which comprises monocytes, to a shear force such that said monocytes are globally activated, b) wherein the method is performed in the absence of photoactivatable agents such as 8-MOP, and UVA, c) wherein the method is performed without the need for addition of a molecular cocktail comprising cytokines; and d) wherein said globally activated monocytes are identified by increased expression of at least HLA-DR, PLAUR or ICAM-1.
A compound of Structure: or a pharmaceutically acceptable salt thereof, wherein: R 1 is H, -CN, halogen, C 1 -C 4 straight or branched alkyl, -O-(C 3 -C 5 cycloalkyl), -O-(C 1 -C 4 straight or branched alkyl) wherein: C 3 -C 5 cycloalkyl optionally includes an oxygen or nitrogen heteroatom; and when R 1 is not H, -CN or halogen, it is optionally substituted with one or more halogens; each R 2 is independently hydrogen, halogen or C 1 -C 4 straight or branched alkyl; R 3 is H, -OH, or halogen; R 21 is H, halogen, C 1 -C 4 straight or branched alkyl, C 3 -C 5 cycloalkyl wherein the C 3 -C 5 cycloalkyl optionally includes an oxygen or nitrogen heteroatom; R 22 is H, halogen, or C 1 -C 2 alkyl; R 24 is H, C 1 -C 4 straight or branched alkyl, -(C 1 -C 4 alkyl) t -OH, -(C 1 -C 4 alkyl) t -O t -(C 3 -C 5 cycloalkyl), or -(C 1 -C 4 alkyl) t -O-(C 1 -C 4 straight or branched alkyl) wherein: t is 0 or 1; the C 3 -C 5 cycloalkyl optionally includes an oxygen or nitrogen heteroatom; L 1 is CR 23 or N; L 2 is CH or N; at least one of L 1 or L 2 is N; and R 23 is H or C 1 -C 4 straight or branched alkyl. R 1 is H, -CN, halogen, C 1 -C 4 straight or branched alkyl, -O-(C 3 -C 5 cycloalkyl), -O-(C 1 -C 4 straight or branched alkyl) wherein: C 3 -C 5 cycloalkyl optionally includes an oxygen or nitrogen heteroatom; and when R 1 is not H, -CN or halogen, it is optionally substituted with one or more halogens; C 3 -C 5 cycloalkyl optionally includes an oxygen or nitrogen heteroatom; and when R 1 is not H, -CN or halogen, it is optionally substituted with one or more halogens; each R 2 is independently hydrogen, halogen or C 1 -C 4 straight or branched alkyl; R 3 is H, -OH, or halogen; R 21 is H, halogen, C 1 -C 4 straight or branched alkyl, C 3 -C 5 cycloalkyl wherein the C 3 -C 5 cycloalkyl optionally includes an oxygen or nitrogen heteroatom; R 22 is H, halogen, or C 1 -C 2 alkyl; R 24 is H, C 1 -C 4 straight or branched alkyl, -(C 1 -C 4 alkyl) t -OH, -(C 1 -C 4 alkyl) t -O t -(C 3 -C 5 cycloalkyl), or -(C 1 -C 4 alkyl) t -O-(C 1 -C 4 straight or branched alkyl) wherein: t is 0 or 1; the C 3 -C 5 cycloalkyl optionally includes an oxygen or nitrogen heteroatom; t is 0 or 1; the C 3 -C 5 cycloalkyl optionally includes an oxygen or nitrogen heteroatom; L 1 is CR 23 or N; L 2 is CH or N; at least one of L 1 or L 2 is N; and R 23 is H or C 1 -C 4 straight or branched alkyl.
A fusion polypeptide, comprising an arginine deiminase that is covalently linked to a Tumor Necrosis Factor superfamily ligand, wherein the TNF superfamily ligand is a TNF-related apoptosis-inducing ligand (TRAIL) polypeptide, and wherein the ADI comprises, consists, or consists essentially of an amino acid sequence that is at least 98%, or 99% identical to any one of SEQ ID NOs: 9, 37, 38, 50, and 57-68, and wherein the TRAIL polypeptide comprises, consists, or consists essentially of an amino acid sequence that is at least 98%, or 99% identical to a sequence selected from SEQ ID NO: 70 and 69, and wherein the fusion polypeptide forms a hexameric complex of six ADI-TRAIL and/or TRAIL-ADI fusion polypeptides. wherein the TNF superfamily ligand is a TNF-related apoptosis-inducing ligand (TRAIL) polypeptide, and wherein the ADI comprises, consists, or consists essentially of an amino acid sequence that is at least 98%, or 99% identical to any one of SEQ ID NOs: 9, 37, 38, 50, and 57-68, and wherein the TRAIL polypeptide comprises, consists, or consists essentially of an amino acid sequence that is at least 98%, or 99% identical to a sequence selected from SEQ ID NO: 70 and 69, and wherein the fusion polypeptide forms a hexameric complex of six ADI-TRAIL and/or TRAIL-ADI fusion polypeptides.
A method of receiving a data stream from a transmitting device via a communication link, wherein symbols of the data stream are transmitted at a link symbol clock rate, the data stream comprising a stream of pixels that are clocked according to a stream clock rate, which is different from the link symbol clock rate, the data stream comprising time stamp values M and N, and a reference value, the method comprising providing a regenerated local stream clock according to the link symbol clock rate, and the time stamp values M and N, characterized in that the method further comprises: recovering blank start symbols and blank end symbols from the received data stream, for every line of pixel data, wherein M and N are updated once per several lines of pixel data; counting a number of cycles of the regenerated local stream clock between consecutive blank end or blank start symbols; comparing the counted number of cycles of the regenerated local stream clock with the reference value, and adjusting a rate of the regenerated local stream clock based on the comparison, wherein the adjusting is performed more often than updates to M and N are received. recovering blank start symbols and blank end symbols from the received data stream, for every line of pixel data, wherein M and N are updated once per several lines of pixel data; counting a number of cycles of the regenerated local stream clock between consecutive blank end or blank start symbols; comparing the counted number of cycles of the regenerated local stream clock with the reference value, and adjusting a rate of the regenerated local stream clock based on the comparison, wherein the adjusting is performed more often than updates to M and N are received.
A topical pharmaceutical composition comprising: - a therapeutically active ingredient selected from the group consisting of sirolimus, everolimus, tacrolimus, pimecrolimus, ridaforolimus, temsirolimus, and zotarolimus, - a hydrophilic component; - a lipophilic component; and - an amphiphilic component, wherein the composition is formulated as a microemulsion; wherein the hydrophilic component comprises a combination of water and a liquid glycol which is preferably selected from glycerol, propylene glycol, 1,2-pentylene glycol, and polyethylene glycol; and wherein the ratio of water to the liquid glycol is in the range from 1: 10 to 10: 1. - a therapeutically active ingredient selected from the group consisting of sirolimus, everolimus, tacrolimus, pimecrolimus, ridaforolimus, temsirolimus, and zotarolimus, - a hydrophilic component; - a lipophilic component; and - an amphiphilic component,
An apparatus for sonicating a patient, said apparatus comprising: an ultrasound array having a plurality of transducers (42, 42,..., 42); a driving module for driving said transducers (42, 42,..., 42); and a controller connected to the driving module by multiple channels (30, 30,..., 30) to drive said transducers (42, 42,..., 42) concurrently at two different frequencies. characterized in that the controller provides a signal being the superposition of two or more frequencies to a single channel, thus enabling the one transducer associated with said single channel to be driven simultaneously at said two or more frequencies. an ultrasound array having a plurality of transducers (42, 42,..., 42); a driving module for driving said transducers (42, 42,..., 42); and a controller connected to the driving module by multiple channels (30, 30,..., 30) to drive said transducers (42, 42,..., 42) concurrently at two different frequencies. characterized in that the controller provides a signal being the superposition of two or more frequencies to a single channel, thus enabling the one transducer associated with said single channel to be driven simultaneously at said two or more frequencies.