mhurhangee/ep-ind-claims huggingface dataset:
An orbital shaker comprising - a shaker table with a surface for supporting a load (6, 7, 8, 9), - a rotor rotatable around an axis of rotation, - a drive adapted to produce the rotational movement of the rotor, - a rotary joint, which connects the rotor and the shaker table to one another so that they can rotate freely about a joint axis, which runs with a parallel offset (e) to the axis of rotation, - a guide (12, 13) which is adapted in such a manner that all points of the surface of the shaker table describe a circular orbit with the same diameter as the rotor rotates, which diameter corresponds to twice the parallel offset, characterized by a balancing device for the automatic compensation of imbalance-induced forces and/or moments comprising: - at least one balancing plane which is perpendicular to the axis of rotation, - at least one circular orbit arranged concentrically around the axis of rotation in each balancing plane, - a plurality of compensating masses (101/110)arranged freely movably on each circular orbit, - a rotational damping mechanism adapted in such a mannerthat when there is a deviation between the rotational speed of the compensating masses (101/110) and the rotational speed of the rotor about the axis of rotation, a moment acts on the compensating masses (101/110), - a guide system (102, 103, 106) adapted in such a manner thatit allows exclusively a translational movement of the rotor within a plane which is perpendicular to the axis of rotation and/or a tilting of the rotor around two axes which are at right angles to each other and which lie in a plane perpendicular to the axis of rotation. - a shaker table with a surface for supporting a load (6, 7, 8, 9), - a rotor rotatable around an axis of rotation, - a drive adapted to produce the rotational movement of the rotor, - a rotary joint, which connects the rotor and the shaker table to one another so that they can rotate freely about a joint axis, which runs with a parallel offset (e) to the axis of rotation, - a guide (12, 13) which is adapted in such a manner that all points of the surface of the shaker table describe a circular orbit with the same diameter as the rotor rotates, which diameter corresponds to twice the parallel offset, - at least one balancing plane which is perpendicular to the axis of rotation, - at least one circular orbit arranged concentrically around the axis of rotation in each balancing plane, - a plurality of compensating masses (101/110)arranged freely movably on each circular orbit, - a rotational damping mechanism adapted in such a mannerthat when there is a deviation between the rotational speed of the compensating masses (101/110) and the rotational speed of the rotor about the axis of rotation, a moment acts on the compensating masses (101/110), - a guide system (102, 103, 106) adapted in such a manner thatit allows exclusively a translational movement of the rotor within a plane which is perpendicular to the axis of rotation and/or a tilting of the rotor around two axes which are at right angles to each other and which lie in a plane perpendicular to the axis of rotation.
A laser cutting nozzle comprising: an inner nozzle that exhibits a tube shape having a through hole on an axis and having a diameter decreasing on a first end portion side and includes a notch (1a1-1a3) extending in the axis direction along an outer peripheral surface (1b1) on a second end portion side; and an outer nozzle that is fitted to the outer peripheral surface (1b1) of the inner nozzle and includes a vent passage including the notch (1a1-1a3) and communicating between the first end portion and the second end portion in the axis direction, wherein a minimum flow cross-sectional area (Smin) of the vent passage matches an opening area of the notch (1a1-1a3) in an end surface on the second end portion side, characterized in that an upper end surface and a lower end surface of the inner nozzle in the nozzle are positioned on substantially the same surfaces, namely the same axial positions, as the upper end surface and the lower end surface of the outer nozzle, respectively. an inner nozzle that exhibits a tube shape having a through hole on an axis and having a diameter decreasing on a first end portion side and includes a notch (1a1-1a3) extending in the axis direction along an outer peripheral surface (1b1) on a second end portion side; and an outer nozzle that is fitted to the outer peripheral surface (1b1) of the inner nozzle and includes a vent passage including the notch (1a1-1a3) and communicating between the first end portion and the second end portion in the axis direction, wherein a minimum flow cross-sectional area (Smin) of the vent passage matches an opening area of the notch (1a1-1a3) in an end surface on the second end portion side, characterized in that an upper end surface and a lower end surface of the inner nozzle in the nozzle are positioned on substantially the same surfaces, namely the same axial positions, as the upper end surface and the lower end surface of the outer nozzle, respectively.
An in vitro method for increasing adeno-associated virus vector infectivity of cells, wherein said method comprises contacting cells with said adeno-associated virus vector and a U2 snRNP spliceosome inhibitor.
Control method for a transmission arrangement having a transmission clutch unit, comprising an input shaft for driving the transmission clutch unit, a first and a second output shaft (16, 18) which can be connected, for the purpose of providing drive, to a transmission unit which is arranged downstream in the force flux, a first and second clutch (20, 22) with a common clutch drive element, wherein the first output shaft can be connected in terms of drive as required to the input shaft via the first clutch and the second output shaft can be connected in terms of drive as required to the input shaft via the second clutch, a planetary gear mechanism with a ring gear and a planetary gear carrier, wherein the ring gear can be locked against rotation with respect to a fixed housing of the transmission clutch unit by means of a reverse clutch, in order to bring about a reversing drive connection of the input shaft to the second output shaft, characterized in that the planetary gear carrier is connected so as to circulate together with the clutch drive element about a rotation axis which is defined by the input shaft, wherein a transmission unit with a plurality of gear stages and a transmission output shaft is arranged downstream of the transmission clutch unit in the force flux, wherein at least one first gear stage can be driven by the first output shaft and at least one second gear stage can be driven by the second output shaft, comprising the steps: driving the at least one first gear stage via the first output shaft in a first operating direction, pre-engaging the at least one second gear stage which can be driven by the second output shaft, reversing from the first operating direction into a second operating direction, and the driving the at least one second gear stage via the second output shaft as well as adjusting an input rotational speed (n E) which is present at the input shaft, with the objective of setting an output rotational speed (n A) of the transmission output shaft which is provided for the second operating direction, in order to compensate different transmission ratios in the first gear stage and in the second gear stage.
Distribution machine with a supply device for a self-regulated pneumatic supply from a main reservoir containing product toward at least one auxiliary reservoir according to its filling rate via a respective tight duct, each auxiliary reservoir comprising an air exhaust device and a distribution unit for distributing the product comprising a supply chamber and a rotary regulating element, characterized in that the air exhaust device is configured to extend substantially below the overflow spot of the said supply chamber.
A thermoplastically processable polyurethane elastomer which is readily releasable from a mold having a Shore A hardness of up to 80 Shore A, a tensile strength of greater than 10 MPa, a low degree of cold hardening being defined by a relative difference between the hardness value of the TPU at ambient temperature (approximately 23°C) before exposure to a sub-ambient temperature and the hardness value of the TPU at ambient temperature after exposure to a temperature of 4°C for a period of five days of up to 6%, and which is the reaction product of: A) at least one branched hydroxyl-terminated polyester having a number average molecular weight of from 800 to 5,000, which is the reaction product of: neopentyl glycol and adipic acid with B) at least one diisocyanate and C) at least one diol chain extender having a molecular weight of from 60 to 400, formed in the absence of a plasticizer by reacting A), B) and C) at an NCO:OH molar ratio of from 0.9:1 to 1.1:1. A) at least one branched hydroxyl-terminated polyester having a number average molecular weight of from 800 to 5,000, which is the reaction product of: neopentyl glycol and adipic acid with B) at least one diisocyanate and C) at least one diol chain extender having a molecular weight of from 60 to 400, formed in the absence of a plasticizer by reacting A), B) and C) at an NCO:OH molar ratio of from 0.9:1 to 1.1:1.
A kit comprising a rack comprising at least two positive control vials, wherein each of said positive control vials comprises a stock solution of a mixture of at least two positive control nucleic acids, wherein said at least two positive control nucleic acids are the same in the at least two positive control vials, wherein one positive control vial may have a different concentration of the positive control nucleic acids than another positive control nucleic acid in the same rack; a label indicating a single target nucleic acid to be detected with the kit components, wherein said target nucleic acid corresponds to one of the positive control nucleic acids in said stock solution, and a master mix vial comprising a master mix comprising reagents for amplification of said target nucleic acid and the corresponding positive control nucleic acid, and wherein the kit does not comprise a master mix comprising reagents for amplification of target nucleic acids corresponding to the at least one positive control nucleic acid not corresponding to said target nucleic acid indicated on the label, said at least one positive control nucleic acid not corresponding to said target nucleic acid indicated on the label being present in the stock solution of said positive control vial.
A curable composition comprising: a mixture of a first crosslinked polyorganosiloxane including a siloxane unit of Formula A and a siloxane unit of Formula B, having a ratio (B/(A+B)) of the molar amount of the siloxane unit of Formula B to the total molar amount (A+B) of the siloxane units of Formulas A and B of 0.1 to 0.25, and having a molar ratio (Ar/Si) of an aryl (Ar) group to silicon (Si) atoms of 0.3 or less; and a second crosslinked polyorganosiloxane including a siloxane unit of Formula A and a siloxane unit of Formula B, having a molar ratio B/(A+B) of 0.35 to 0.65, and having a molar ratio Ar/Si of 0.3 or less; and a polyorganosiloxane including a hydrogen atom and an aryl group, which bind to a silicon atom, having a molar ratio Ar/Si of 0.25 or more, and having 3 to 10 silicon atoms; [Formula A] (R a 3 SiO 1/2) [Formula B] (R b R a 2 SiO 1/2) wherein R a is an alkyl group, and R b is an alkenyl group; wherein the second crosslinked polyorganosiloxane is included in the mixture at 5 to 2,000 parts by weight with respect to 100 parts by weight of the first crosslinked po lyorgano silo xane. a mixture of a first crosslinked polyorganosiloxane including a siloxane unit of Formula A and a siloxane unit of Formula B, having a ratio (B/(A+B)) of the molar amount of the siloxane unit of Formula B to the total molar amount (A+B) of the siloxane units of Formulas A and B of 0.1 to 0.25, and having a molar ratio (Ar/Si) of an aryl (Ar) group to silicon (Si) atoms of 0.3 or less; and a second crosslinked polyorganosiloxane including a siloxane unit of Formula A and a siloxane unit of Formula B, having a molar ratio B/(A+B) of 0.35 to 0.65, and having a molar ratio Ar/Si of 0.3 or less; and a first crosslinked polyorganosiloxane including a siloxane unit of Formula A and a siloxane unit of Formula B, having a ratio (B/(A+B)) of the molar amount of the siloxane unit of Formula B to the total molar amount (A+B) of the siloxane units of Formulas A and B of 0.1 to 0.25, and having a molar ratio (Ar/Si) of an aryl (Ar) group to silicon (Si) atoms of 0.3 or less; and a second crosslinked polyorganosiloxane including a siloxane unit of Formula A and a siloxane unit of Formula B, having a molar ratio B/(A+B) of 0.35 to 0.65, and having a molar ratio Ar/Si of 0.3 or less; and a polyorganosiloxane including a hydrogen atom and an aryl group, which bind to a silicon atom, having a molar ratio Ar/Si of 0.25 or more, and having 3 to 10 silicon atoms; [Formula A] (R a 3 SiO 1/2) [Formula B] (R b R a 2 SiO 1/2) wherein R a is an alkyl group, and R b is an alkenyl group; wherein the second crosslinked polyorganosiloxane is included in the mixture at 5 to 2,000 parts by weight with respect to 100 parts by weight of the first crosslinked po lyorgano silo xane.
An exhaust after treatment system (100, 200, 300) for a vehicle, comprising an exhaust outlet pipe (1a, 1b), having a first end that is connectable to a vehicle engine, for receiving exhaust gases from said vehicle engine, and having an outlet opening at a second end, arranged to eject the outlet gases, a catalytic converter (4, 6), connected to the exhaust outlet pipe (1a, 1b), and an electric heater element which is in heat exchanging contact with the catalytic converter (4, 6) and adapted for pre-heating the catalytic converter (4, 6), a gas pump, which is with an inlet connected to the exhaust outlet pipe section at or near the first end, the heater element being positioned downstream of the catalytic converter (4,6) with respect to the first end, and the exhaust after treatment system being adapted to, upon the vehicle being started, switch on the heater element and the pump to pump gases from the second end, in_the direction of the first end of the exhaust outlet pipe (1a, 1b), through the catalytic converter (4, 6) for a pre-set period of time prior to passing exhaust gases from the engine towards the outlet opening at the second end., an exhaust outlet pipe (1a, 1b), having a first end that is connectable to a vehicle engine, for receiving exhaust gases from said vehicle engine, and having an outlet opening at a second end, arranged to eject the outlet gases, a catalytic converter (4, 6), connected to the exhaust outlet pipe (1a, 1b), and an electric heater element which is in heat exchanging contact with the catalytic converter (4, 6) and adapted for pre-heating the catalytic converter (4, 6), a gas pump, which is with an inlet connected to the exhaust outlet pipe section at or near the first end, the heater element being positioned downstream of the catalytic converter (4,6) with respect to the first end, and the exhaust after treatment system being adapted to, upon the vehicle being started, switch on the heater element and the pump to pump gases from the second end, in_the direction of the first end of the exhaust outlet pipe (1a, 1b), through the catalytic converter (4, 6) for a pre-set period of time prior to passing exhaust gases from the engine towards the outlet opening at the second end.,
An effective amount of an agent that inhibits or reduces the expression or activity of CD33 protein for use in a method of treating Alzheimer's disease in a subject, wherein the agent is an anti-CD33 antibody that binds to a cell-surface receptor encoded by CD33.
A gearbox comprises: a sun gear, a plurality of planetary gears supported by a rotating frame and meshed with the sun gear, and a housing with an internal ring gear, the internal ring gear provided on the inner surface of the housing to mesh with the plurality of planetary gears; and wherein each of the plurality of planetary gears comprises a first gear and a second gear coaxially connected to each other along an axial direction and rotating synchronously, the first gear meshed with the sun gear, and the second gear meshed with the internal ring gear of the housing; the rotating frame received in the housing comprises an upper frame and a lower frame, each of the plurality of planetary gears is arranged between the upper frame and the lower frame, the lower frame is supported by a flange connected to the housing, the sun gear is driven to rotate so as to operate the rotating frame and characterised in that the a protrusion extends from the upper frame toward the sun gear and is configured to maintain a gap with the sun gear to prevent the sun gear from excessive displacement. each of the plurality of planetary gears comprises a first gear and a second gear coaxially connected to each other along an axial direction and rotating synchronously, the first gear meshed with the sun gear, and the second gear meshed with the internal ring gear of the housing; the rotating frame received in the housing comprises an upper frame and a lower frame, each of the plurality of planetary gears is arranged between the upper frame and the lower frame, the lower frame is supported by a flange connected to the housing, the sun gear is driven to rotate so as to operate the rotating frame and characterised in that the a protrusion extends from the upper frame toward the sun gear and is configured to maintain a gap with the sun gear to prevent the sun gear from excessive displacement.
Device for melting adhesive, having a melting grill that has a multiplicity of passage openings, and having heating elements, wherein the melting grill is heatable by means of the heating elements and melted adhesive by means of the hot melting grill is dischargeable through the passage openings, the melting grill on that side thereof that faces the adhesive to be melted having ribs, wherein the melting grill has rods that are disposed beside one another and ribs that are disposed on the rods, the rods and the ribs being heatable by means of the heating elements, wherein ribs of adjacent rods are aligned so as to be directed toward one another, characterized in that the passage cross sections of the passage openings between the rods are modifiable by rotating rods of the melting grill.
A method of transforming source image data for a source image, the source image data being in a source format having a transparency channel, the method comprising: determining, from the source image data, colour information and transparency information for each source pixel of the source image; characterized in that the method further comprises: generating a transformed image including a first region and a second region by: for each source pixel of the source image, basing colour information of a corresponding pixel of the first region on the colour information of that source pixel; and basing colour information of a corresponding pixel of the second region on the transparency information of that source pixel; and saving the transformed image in a target format that lacks a transparency channel. determining, from the source image data, colour information and transparency information for each source pixel of the source image; characterized in that the method further comprises: generating a transformed image including a first region and a second region by: for each source pixel of the source image, basing colour information of a corresponding pixel of the first region on the colour information of that source pixel; and basing colour information of a corresponding pixel of the second region on the transparency information of that source pixel; and saving the transformed image in a target format that lacks a transparency channel. generating a transformed image including a first region and a second region by: for each source pixel of the source image, basing colour information of a corresponding pixel of the first region on the colour information of that source pixel; and basing colour information of a corresponding pixel of the second region on the transparency information of that source pixel; and saving the transformed image in a target format that lacks a transparency channel. for each source pixel of the source image, basing colour information of a corresponding pixel of the first region on the colour information of that source pixel; and basing colour information of a corresponding pixel of the second region on the transparency information of that source pixel; and basing colour information of a corresponding pixel of the first region on the colour information of that source pixel; and basing colour information of a corresponding pixel of the second region on the transparency information of that source pixel; and saving the transformed image in a target format that lacks a transparency channel.
Fuel channel for a nuclear power boiling water reactor, which fuel channel is configured to include a bundle of fuel rods with nuclear fuel, wherein the fuel channel is made of a sheet material and has an elongated shape and thus defines a longitudinal direction, wherein the fuel channel has a plurality of sides which have an elongated shape in said longitudinal direction and which are connected to each other such that a corner with an elongated shape is formed where two adjacent sides meet, wherein the sides are connected to each other such that the fuel channel thus has as many corners as sides, wherein each side defines an inside (11a, 12a, 13a, 14a), in the fuel channel, and an outside (11b, 12b, 13b, 14b), at the outside of the fuel channel, wherein in at least one of said corners the sheet materials from the two adjacent sides (11, 12) overlap with each other such that there is a corner region with double sheet material consisting of the overlapping sheet material from one of the two sides and the overlapping sheet material from the other of the two sides, characterized in that in said at least one corner, or in more than one of or in all of said corners, the sheet materials from the two adjacent sides (e.g. 11, 12) overlap with each other in such a manner that in the overlapping region a space is formed between the overlapping sheet material from one of the two sides and the overlapping sheet material from the other of the two sides.
An apparatus for facilitating delivery of a fluid to the respiratory tract of a subject, comprising a fluid line substrate having conduits (14, 16) for transmission of fluid, a support for stabilizing the substrate with respect to a supporting surface, and a subject port formed in the substrate and arranged for delivery of fluid to a subject placed proximate the subject port, the conduits (14, 16) comprising a first conduit having a first conduit outlet which opens into the subject port, whereby fluid may be delivered to the subject port via the first conduit, and a second conduit having a second conduit inlet communicating with the subject port, whereby fluid may flow from the subject port into the second conduit, characterized in that the second conduit inlet being positioned distally with respect to the subject port from the first conduit outlet, the fluid line substrate is a block of material in the form of a prism, the conduits (14, 16) are formed in the block of material and the support is a first surface of the block of material, the first surface is one or more of the surfaces of the prism, which is arranged to mount the block on a supporting surface and wherein the subject port is formed in a further surface of the block, the further surface being adjacent the first surface.