A cryotherapy apparatus comprising: a heat exchanger mounted in an exchanger enclosure; a cryotherapy chamber configured to receive at least a portion of a body of a patient designated to receive cryotherapy; a nitrogen supply conduit configured to supply cryogenic nitrogen to the heat exchanger; a nitrogen exhaust conduit configured to exhaust nitrogen from the heat exchanger; an air return conduit configured to flow warmed return air from the cryotherapy chamber to the heat exchanger enclosure; an air supply conduit configured to flow chilled air from the heat exchanger enclosure to the cryotherapy chamber; a variable speed fan configured to cause a flow rate of chilled air through a loop including the air return conduit, the heat exchanger, the air supply conduit, and the cryotherapy chamber; and a controller programmed to control the flow rate of chilled air to the cryotherapy chamber by regulating the speed of the variable speed fan according to a treatment protocol, characterized in that the controller is further programmed to provide customized treatment protocols based one or more of: a characteristic of the patient being treated, a type of treatment required, a type of injury being treated, a type of athletic activity from which recovery is desired, and a portion of the body requiring treatment, wherein the controller is further programmed to provide customized treatment protocols taking into account a customization factor based one or more of a patient's susceptibility to cold, age, and athletic type; and/or the controller is further programmed to provide customized treatment protocols taking into account a personalization factor based on one or more of a patient's body height, mass, surface area, body surface area-to-mass ratio, body fat percentage, lean body mass, body mass index, and fat free mass index; and/or the controller is further programmed to provide customized treatment protocols taking into account an adaptation factor based on one or both of treatment frequency and a treatment cycle. a heat exchanger mounted in an exchanger enclosure; a cryotherapy chamber configured to receive at least a portion of a body of a patient designated to receive cryotherapy; a nitrogen supply conduit configured to supply cryogenic nitrogen to the heat exchanger; a nitrogen exhaust conduit configured to exhaust nitrogen from the heat exchanger; an air return conduit configured to flow warmed return air from the cryotherapy chamber to the heat exchanger enclosure; an air supply conduit configured to flow chilled air from the heat exchanger enclosure to the cryotherapy chamber; a variable speed fan configured to cause a flow rate of chilled air through a loop including the air return conduit, the heat exchanger, the air supply conduit, and the cryotherapy chamber; and a controller programmed to control the flow rate of chilled air to the cryotherapy chamber by regulating the speed of the variable speed fan according to a treatment protocol, characterized in that the controller is further programmed to provide customized treatment protocols based one or more of: a characteristic of the patient being treated, a type of treatment required, a type of injury being treated, a type of athletic activity from which recovery is desired, and a portion of the body requiring treatment, wherein the controller is further programmed to provide customized treatment protocols taking into account a customization factor based one or more of a patient's susceptibility to cold, age, and athletic type; and/or the controller is further programmed to provide customized treatment protocols taking into account a personalization factor based on one or more of a patient's body height, mass, surface area, body surface area-to-mass ratio, body fat percentage, lean body mass, body mass index, and fat free mass index; and/or the controller is further programmed to provide customized treatment protocols taking into account an adaptation factor based on one or both of treatment frequency and a treatment cycle. the controller is further programmed to provide customized treatment protocols taking into account a customization factor based one or more of a patient's susceptibility to cold, age, and athletic type; and/or the controller is further programmed to provide customized treatment protocols taking into account a personalization factor based on one or more of a patient's body height, mass, surface area, body surface area-to-mass ratio, body fat percentage, lean body mass, body mass index, and fat free mass index; and/or the controller is further programmed to provide customized treatment protocols taking into account an adaptation factor based on one or both of treatment frequency and a treatment cycle.