mhurhangee/ep-ind-claims huggingface dataset:
A method for measuring fibroblast growth factor-23 (hereinafter indicated as FGF-23) in a sample, wherein the method comprises the steps of: reacting in an aqueous medium, FGF-23 in a sample with a magnetic particle, and a first antibody or a fragment thereof which binds to FGF-23 and is not bound to the magnetic particle, to form on the magnetic particle an immunocomplex 1 comprising FGF-23 and the first antibody or a fragment thereof which binds to FGF-23, wherein the magnetic particle is fixed to one of two substances with affinity to each other, and the first antibody or a fragment thereof is bound to the other of the two substances with affinity to each other, wherein the sample is serum or plasma; collecting the magnetic particle in the reaction mixture after step by magnetic force, and separating the magnetic particle collected by magnetic force from the other components; reacting the immunocomplex 1 on the magnetic particle with a second antibody or a fragment thereof which binds to FGF-23, to form on the magnetic particle an immunocomplex 2 comprising the first antibody or a fragment thereof which binds to FGF-23, FGF-23, and the second antibody or a fragment thereof which binds to FGF-23; collecting the magnetic particle in the reaction mixture after step by magnetic force, and separating the magnetic particle collected by magnetic force from the other components; and measuring the immunocomplex 2 on the magnetic particle separated in step. reacting in an aqueous medium, FGF-23 in a sample with a magnetic particle, and a first antibody or a fragment thereof which binds to FGF-23 and is not bound to the magnetic particle, to form on the magnetic particle an immunocomplex 1 comprising FGF-23 and the first antibody or a fragment thereof which binds to FGF-23, wherein the magnetic particle is fixed to one of two substances with affinity to each other, and the first antibody or a fragment thereof is bound to the other of the two substances with affinity to each other, wherein the sample is serum or plasma; collecting the magnetic particle in the reaction mixture after step by magnetic force, and separating the magnetic particle collected by magnetic force from the other components; reacting the immunocomplex 1 on the magnetic particle with a second antibody or a fragment thereof which binds to FGF-23, to form on the magnetic particle an immunocomplex 2 comprising the first antibody or a fragment thereof which binds to FGF-23, FGF-23, and the second antibody or a fragment thereof which binds to FGF-23; collecting the magnetic particle in the reaction mixture after step by magnetic force, and separating the magnetic particle collected by magnetic force from the other components; and measuring the immunocomplex 2 on the magnetic particle separated in step.
A display apparatus free of an additional backlight assembly having a receiving container, the display apparatus comprising: a covering part; a display panel under the covering part; the covering part entirely covering the display panel; an upper frame attached to the underside of the covering part, the upper frame comprising a first combining portion, the upper frame being disposed around the display panel, wherein the upper frame and the display panel are disposed not to overlap with each other when viewed from a top of the covering part; and alower frame being disposed under the upper frame, the lower frame is fixed to the upper frame through the first combining portion to support the display panel and overlaps only a peripheral portion of the display panel, wherein the lower frame includes an opening exposing a display area of the display panel except for the overlapped peripheral portion of the display panel. a covering part; a display panel under the covering part; the covering part entirely covering the display panel; an upper frame attached to the underside of the covering part, the upper frame comprising a first combining portion, the upper frame being disposed around the display panel, wherein the upper frame and the display panel are disposed not to overlap with each other when viewed from a top of the covering part; and alower frame being disposed under the upper frame, the lower frame is fixed to the upper frame through the first combining portion to support the display panel and overlaps only a peripheral portion of the display panel, wherein the lower frame includes an opening exposing a display area of the display panel except for the overlapped peripheral portion of the display panel.
Device (10; 10a) for encapsulating a component with plastics material, having at least two tool halves (11, 12), which in a closed arrangement for encapsulating the component form a receptacle for the component, having an injection channel for feeding the liquefied plastics material into the region of the receptacle and having a single holding element for positioning the component in the receptacle, the holding element being movable into a first position, for positioning the component in the receptacle, and into a second position, for preferably completely encapsulating the component with the plastics material, wherein the holding element holds the component in the region of the receptacle by interlocking or clamping engagement, and wherein the holding element is formed in a substantially pin-shaped manner, characterized in that the holding element is radially surrounded, at least in certain regions, by a tubular element (23; 23a) serving for controlling the flow of the plastics material into the receptacle, and in that the element (23; 23a) is movably arranged coaxially in relation to the holding element.
An aircraft comprising: a fuselage comprising: a wiring racetrack comprising: a first wire group comprising one or more wires of exclusively a first category; a second wire group comprising one or more wires of exclusively a second category distinct from the first category; a wiring pallet comprising a first track and a second track, wherein the one or more wires of the first category are contained exclusively within the first track, and wherein the one or more wires of the second category are contained exclusively within the second track; a first connector (310A; 314A) electrically coupled to each of the wires of the first wire group within or at the end of the first track; and a second connector (310B; 314B) electrically coupled to each of the wires of the second wire group within or at the end of the second track; and secondary wiring comprising one or more connectors electrically coupled to the first connector, the second connector, or to both the first connector and the second connector; wherein the first wire group is electrically coupled to a first aircraft system and the second wire group is electrically coupled to a second aircraft system. a wiring racetrack comprising: a first wire group comprising one or more wires of exclusively a first category; a second wire group comprising one or more wires of exclusively a second category distinct from the first category; a wiring pallet comprising a first track and a second track, wherein the one or more wires of the first category are contained exclusively within the first track, and wherein the one or more wires of the second category are contained exclusively within the second track; a first connector (310A; 314A) electrically coupled to each of the wires of the first wire group within or at the end of the first track; and a second connector (310B; 314B) electrically coupled to each of the wires of the second wire group within or at the end of the second track; and a first wire group comprising one or more wires of exclusively a first category; a second wire group comprising one or more wires of exclusively a second category distinct from the first category; a wiring pallet comprising a first track and a second track, wherein the one or more wires of the first category are contained exclusively within the first track, and wherein the one or more wires of the second category are contained exclusively within the second track; a first connector (310A; 314A) electrically coupled to each of the wires of the first wire group within or at the end of the first track; and a second connector (310B; 314B) electrically coupled to each of the wires of the second wire group within or at the end of the second track; and secondary wiring comprising one or more connectors electrically coupled to the first connector, the second connector, or to both the first connector and the second connector; wherein the first wire group is electrically coupled to a first aircraft system and the second wire group is electrically coupled to a second aircraft system.
A method of detecting a subtype of cancer with DNA damage repair deficiency related immune signalling in an individual having cancer comprising: a. measuring in a test sample obtained from the individual expression levels of CXCL10, MX1, IDO1 or IFI44L and at least 1 additional biomarker selected from Table 2B; b. deriving a test score that captures the expression levels; c. providing a threshold score comprising information correlating the test score and the detection of the subtype of cancer with DNA damage repair deficiency related immune signalling; d. and comparing the test score to the threshold score; wherein the cancer with DNA damage repair deficiency related immune signalling is detected when the test score exceeds the threshold score. a. measuring in a test sample obtained from the individual expression levels of CXCL10, MX1, IDO1 or IFI44L and at least 1 additional biomarker selected from Table 2B; b. deriving a test score that captures the expression levels; c. providing a threshold score comprising information correlating the test score and the detection of the subtype of cancer with DNA damage repair deficiency related immune signalling; d. and comparing the test score to the threshold score; wherein the cancer with DNA damage repair deficiency related immune signalling is detected when the test score exceeds the threshold score.
A loom including a rotary shaft bridged to a pair of side frames (3, 3) with being supported via bearings each provided in corresponding one of the side frames (3, 3), the rotary shaft including: solid shaft-shaped shaft parts (5a, 5c) supported by corresponding one of the side frames (3, 3); and a hollow pipe-shaped main body part located between the shaft parts (5a, 5c), the loom comprising: a bearing structure provided in at least one of existence ranges of the shaft parts (5a, 5c) between the side frames (3, 3) with respect to an axis line direction of the rotary shaft, the bearing structure including: a rolling bearing into which one of the shaft parts (5a, 5c) is fitted; and a support body configured to support the rolling bearing.
An energy storage apparatus comprising a compressible spring extending between a releasing means and a compressing means, said compressing means and releasing means being in a fixedly attached relationship with said compressible spring at two ends thereof, said compressing means and releasing means being rotatable at different speeds so as to compress the compressible spring at one longitudinal side thereof while simultaneously releasing the compressible spring at the other longitudinal side, characterized by said energy storage apparatus further comprising a hydraulic jack continuously driven by a hydraulic pump in the manner that said compressible spring is compressed by said compressing means to which rotational movement is imparted by said hydraulic jack and, said hydraulic jack is periodically released by a hydraulic valve in constant intervals to provide continuous unidirectional rotary movement of constant speed to said compressing means.
A data transmission method, wherein the method is applied to an optical transport network, and the method comprises: determining total bandwidth ofN slice containers based on a reference unit, wherein the reference unit is minimum bandwidth of a service of transmitting data, the total bandwidth of the N slice containers is an integer multiple of the reference unit, each slice container comprises slice data, the slice data is data obtained after slice processing is performed on the data, and N is an integer greater than or equal to 2; determining, based on the total bandwidth of the N slice containers and an available link resource, M links for carrying the N slice containers, wherein M is an integer greater than or equal to 1; and adding the N slice containers to the M links, and sending the data to a receive end (1401, 1402) through the different links, characterised in that, each slice container further comprises a sequence identifier, the sequence identifier is obtained by encoding the N slice containers according to a preset rule, and the sequence identifier is used to indicate sorting of the N slice containers; wherein the M links comprise a first link and a second link; and the adding the N slice containers to the M links comprises: adding K slice containers in the N slice containers based on a bandwidth ratio of the first link to the second link, wherein a quantity of slice containers to be carried on the first link and a quantity of slice containers to be carried on the second link are determined based on the bandwidth ratio of the first link to the second link, and K ≤ N. determining total bandwidth ofN slice containers based on a reference unit, wherein the reference unit is minimum bandwidth of a service of transmitting data, the total bandwidth of the N slice containers is an integer multiple of the reference unit, each slice container comprises slice data, the slice data is data obtained after slice processing is performed on the data, and N is an integer greater than or equal to 2; determining, based on the total bandwidth of the N slice containers and an available link resource, M links for carrying the N slice containers, wherein M is an integer greater than or equal to 1; and adding the N slice containers to the M links, and sending the data to a receive end (1401, 1402) through the different links, characterised in that, each slice container further comprises a sequence identifier, the sequence identifier is obtained by encoding the N slice containers according to a preset rule, and the sequence identifier is used to indicate sorting of the N slice containers; wherein the M links comprise a first link and a second link; and the adding the N slice containers to the M links comprises: adding K slice containers in the N slice containers based on a bandwidth ratio of the first link to the second link, wherein a quantity of slice containers to be carried on the first link and a quantity of slice containers to be carried on the second link are determined based on the bandwidth ratio of the first link to the second link, and K ≤ N.
A machine for breaking and reducing the bulk size of one or more objects, the machine comprising: a frame; a reception chamber for receiving and accommodating the one or more objects to be broken; a drum rotatably coupled to the frame and configured to oscillate relative to the frame between a first, fully retracted position and a second, fully advanced position about a longitudinal rotational axis; a cutting member coupled to the drum and extending therefrom, the cutting member being configured to penetrate through one or more of the objects in the reception chamber during operation as the drum rotates from the first position to the second position during each oscillation cycle, wherein the cutting member comprises a cutting head having a main body extending laterally from the drum and extending longitudinally along a length of the drum; and a breaking screen comprising a plurality of breaking plates extending along a plane substantially orthogonal to a longitudinal axis of the drum configured to cause further breakdown of the one or more pieces of the one or more objects during operation as the drum rotates toward the second position during each oscillation cycle and forces the one or more pieces against the breaking plates, wherein each breaking plate comprises a curved portion configured to wrap around a portion of a circumference of the drum and the series of breaking plates form a magazine within a path traversed by the cutting head during operation for supporting the one or more objects received within the reception chamber during operation. a frame; a reception chamber for receiving and accommodating the one or more objects to be broken; a drum rotatably coupled to the frame and configured to oscillate relative to the frame between a first, fully retracted position and a second, fully advanced position about a longitudinal rotational axis; a cutting member coupled to the drum and extending therefrom, the cutting member being configured to penetrate through one or more of the objects in the reception chamber during operation as the drum rotates from the first position to the second position during each oscillation cycle, wherein the cutting member comprises a cutting head having a main body extending laterally from the drum and extending longitudinally along a length of the drum; and a breaking screen comprising a plurality of breaking plates extending along a plane substantially orthogonal to a longitudinal axis of the drum configured to cause further breakdown of the one or more pieces of the one or more objects during operation as the drum rotates toward the second position during each oscillation cycle and forces the one or more pieces against the breaking plates, wherein each breaking plate comprises a curved portion configured to wrap around a portion of a circumference of the drum and the series of breaking plates form a magazine within a path traversed by the cutting head during operation for supporting the one or more objects received within the reception chamber during operation.
Apparatus suitable for facilitating delivery of a therapeutic agent, the apparatus comprising: a pressure source; a container having proximal and distal ends with an inlet port at the proximal end for receiving a fluid from the pressure source; a therapeutic agent disposed within the container; and a tube member having proximal and distal ends, characterized in that: the proximal end of the tube member is positioned within the container; and the apparatus further comprises a flow obstruction member positioned within the container between the inlet port and the proximal end of the tube member, the flow obstruction member structured to direct fluid around the flow obstruction member and towards the proximal end of the tube member, the flow obstruction member and the tube member being spaced relative to each other to cause the fluid to flow around the obstruction member and draw the therapeutic agent into the tube member and direct the therapeutic agent distally therethrough. a pressure source; a container having proximal and distal ends with an inlet port at the proximal end for receiving a fluid from the pressure source; a therapeutic agent disposed within the container; and a tube member having proximal and distal ends, characterized in that: the proximal end of the tube member is positioned within the container; and the apparatus further comprises a flow obstruction member positioned within the container between the inlet port and the proximal end of the tube member, the flow obstruction member structured to direct fluid around the flow obstruction member and towards the proximal end of the tube member, the flow obstruction member and the tube member being spaced relative to each other to cause the fluid to flow around the obstruction member and draw the therapeutic agent into the tube member and direct the therapeutic agent distally therethrough. the proximal end of the tube member is positioned within the container; and the apparatus further comprises a flow obstruction member positioned within the container between the inlet port and the proximal end of the tube member, the flow obstruction member structured to direct fluid around the flow obstruction member and towards the proximal end of the tube member, the flow obstruction member and the tube member being spaced relative to each other to cause the fluid to flow around the obstruction member and draw the therapeutic agent into the tube member and direct the therapeutic agent distally therethrough.
A biosensor, comprising: a measuring layer configured to measure whether reaction to a biological sample has occurred; a lower cover disposed below the measuring layer, and provided with a lower protrusion which protrudes between an open window configured to allow a measurement area of the measuring layer to be exposed and an upper protrusion of an upper cover so that the lower protrusion is spaced apart from the upper protrusion by a predetermined gap and which presses the measuring layer so that a top of the measuring layer upwardly protrudes from the open window through which the biological sample is to be introduced to the measuring layer; and the upper cover disposed on a top of the measuring layer, and provided with the open window and the upper protrusion configured to protrude from an outer portion of the open window in a direction in which the upper protrusion is coupled to the lower cover, wherein the lower protrusion presses the measuring layer so that a bottom of the measuring layer is flattened and the measuring layer is pressed between the upper cover and the lower cover such that the lower protrusion upwardly presses the measuring layer so that a top of the measuring layer is upwardly convex. a measuring layer configured to measure whether reaction to a biological sample has occurred; a lower cover disposed below the measuring layer, and provided with a lower protrusion which protrudes between an open window configured to allow a measurement area of the measuring layer to be exposed and an upper protrusion of an upper cover so that the lower protrusion is spaced apart from the upper protrusion by a predetermined gap and which presses the measuring layer so that a top of the measuring layer upwardly protrudes from the open window through which the biological sample is to be introduced to the measuring layer; and the upper cover disposed on a top of the measuring layer, and provided with the open window and the upper protrusion configured to protrude from an outer portion of the open window in a direction in which the upper protrusion is coupled to the lower cover, wherein the lower protrusion presses the measuring layer so that a bottom of the measuring layer is flattened and the measuring layer is pressed between the upper cover and the lower cover such that the lower protrusion upwardly presses the measuring layer so that a top of the measuring layer is upwardly convex.
An expression system comprising: a. suspension 293 cells, wherein said suspension 293 cells have been adapted for growth under high density conditions b. high density culture medium c. at least one expression enhancer comprising valproic acid (VPA and a sodium salt) in combination with sodium propionate. a. suspension 293 cells, wherein said suspension 293 cells have been adapted for growth under high density conditions b. high density culture medium c. at least one expression enhancer comprising valproic acid (VPA and a sodium salt) in combination with sodium propionate.