Composition comprising collagen and hyaluronic acid for use in a method for repair of a ligament or tendon in a subject, the method comprising: - applying said composition in form of a flexible and bio-compatible patch comprising: - a support layer comprising collagen, wherein the support layer is cell porous, and - a matrix layer comprising collagen and hyaluronic acid to said ligament or tendon, wherein a) the support layer comprises a dried porcine split skin layer; and/or b) the matrix layer further comprises one or more compounds selected from analgesics, anti-inflammatory agents, antibiotics, and agents promoting ligament and/or tendon regeneration, wherein the agents promoting ligament and/or tendon regeneration are selected from the group consisting of: growth factors, Diacerein, Rhein, platelet rich plasma, poly-lactic acid and chitosan, chitosan hydrochloride, carboxymethyl chitosan, chitosan lactate, chitosan acetate, chitosan glutamate, chitosan succinate, N-(2-hydroxy)propyl-3-trimethyl ammonium chitosan chloride, N-trimethylene chitosan chloride, and pharmaceutically acceptable salts thereof; and/or c) the composition further comprises a third layer, which is disposed on the matrix layer such that the matrix layer is sandwiched between the support layer and the third layer. - applying said composition in form of a flexible and bio-compatible patch comprising: - a support layer comprising collagen, wherein the support layer is cell porous, and - a matrix layer comprising collagen and hyaluronic acid to said ligament or tendon, wherein a) the support layer comprises a dried porcine split skin layer; and/or b) the matrix layer further comprises one or more compounds selected from analgesics, anti-inflammatory agents, antibiotics, and agents promoting ligament and/or tendon regeneration, wherein the agents promoting ligament and/or tendon regeneration are selected from the group consisting of: growth factors, Diacerein, Rhein, platelet rich plasma, poly-lactic acid and chitosan, chitosan hydrochloride, carboxymethyl chitosan, chitosan lactate, chitosan acetate, chitosan glutamate, chitosan succinate, N-(2-hydroxy)propyl-3-trimethyl ammonium chitosan chloride, N-trimethylene chitosan chloride, and pharmaceutically acceptable salts thereof; and/or c) the composition further comprises a third layer, which is disposed on the matrix layer such that the matrix layer is sandwiched between the support layer and the third layer. - a support layer comprising collagen, wherein the support layer is cell porous, and - a matrix layer comprising collagen and hyaluronic acid to said ligament or tendon, a) the support layer comprises a dried porcine split skin layer; and/or b) the matrix layer further comprises one or more compounds selected from analgesics, anti-inflammatory agents, antibiotics, and agents promoting ligament and/or tendon regeneration, wherein the agents promoting ligament and/or tendon regeneration are selected from the group consisting of: growth factors, Diacerein, Rhein, platelet rich plasma, poly-lactic acid and chitosan, chitosan hydrochloride, carboxymethyl chitosan, chitosan lactate, chitosan acetate, chitosan glutamate, chitosan succinate, N-(2-hydroxy)propyl-3-trimethyl ammonium chitosan chloride, N-trimethylene chitosan chloride, and pharmaceutically acceptable salts thereof; and/or c) the composition further comprises a third layer, which is disposed on the matrix layer such that the matrix layer is sandwiched between the support layer and the third layer.