A method of preparing a coated medical device comprising: (a) preparing the molecule of formula IV: comprising: reacting a molecule of formula I: with a molecule of formula II: wherein R 1 comprises a polymer, the polymer containing at least one group selected from the group consisting of an acyloxy, alkenyl, alkoxyl, alkyl, alkylcycloalkenyl, alkylcycloalkyl, alkenylcycloalkyl, alkynyl, amino, aralkyl, aryl, cycloalkenyl, cycloalkenylalkyl, cycloalkyl, cycloalkylalkyl, cycloalkylcycloalkyl, halogen, heterocycle, heterocyclic, ketone, N-acylamino, N-containing heterocycle; saturated cyclic, partially saturated cyclic, unsaturated cyclic; saturated ring structure, partially saturated ring structure, unsaturated ring structure, and combinations thereof; and R 2, R 3, R 4, R 5, R 6 and R 7 are alkyls or silanol-terminated alkyls; and wherein n is an integer, 1 ≤ n ≤ 100; and wherein the reaction is carried out at room temperature; and (b) applying the molecule of formula IV obtained in step (a) to the surface of the medical device. (a) preparing the molecule of formula IV: comprising: reacting a molecule of formula I: with a molecule of formula II: wherein R 1 comprises a polymer, the polymer containing at least one group selected from the group consisting of an acyloxy, alkenyl, alkoxyl, alkyl, alkylcycloalkenyl, alkylcycloalkyl, alkenylcycloalkyl, alkynyl, amino, aralkyl, aryl, cycloalkenyl, cycloalkenylalkyl, cycloalkyl, cycloalkylalkyl, cycloalkylcycloalkyl, halogen, heterocycle, heterocyclic, ketone, N-acylamino, N-containing heterocycle; saturated cyclic, partially saturated cyclic, unsaturated cyclic; saturated ring structure, partially saturated ring structure, unsaturated ring structure, and combinations thereof; and R 2, R 3, R 4, R 5, R 6 and R 7 are alkyls or silanol-terminated alkyls; and wherein n is an integer, 1 ≤ n ≤ 100; and wherein the reaction is carried out at room temperature; and reacting a molecule of formula I: with a molecule of formula II: wherein R 1 comprises a polymer, the polymer containing at least one group selected from the group consisting of an acyloxy, alkenyl, alkoxyl, alkyl, alkylcycloalkenyl, alkylcycloalkyl, alkenylcycloalkyl, alkynyl, amino, aralkyl, aryl, cycloalkenyl, cycloalkenylalkyl, cycloalkyl, cycloalkylalkyl, cycloalkylcycloalkyl, halogen, heterocycle, heterocyclic, ketone, N-acylamino, N-containing heterocycle; saturated cyclic, partially saturated cyclic, unsaturated cyclic; saturated ring structure, partially saturated ring structure, unsaturated ring structure, and combinations thereof; and R 2, R 3, R 4, R 5, R 6 and R 7 are alkyls or silanol-terminated alkyls; and wherein n is an integer, 1 ≤ n ≤ 100; and wherein the reaction is carried out at room temperature; and R 1 comprises a polymer, the polymer containing at least one group selected from the group consisting of an acyloxy, alkenyl, alkoxyl, alkyl, alkylcycloalkenyl, alkylcycloalkyl, alkenylcycloalkyl, alkynyl, amino, aralkyl, aryl, cycloalkenyl, cycloalkenylalkyl, cycloalkyl, cycloalkylalkyl, cycloalkylcycloalkyl, halogen, heterocycle, heterocyclic, ketone, N-acylamino, N-containing heterocycle; saturated cyclic, partially saturated cyclic, unsaturated cyclic; saturated ring structure, partially saturated ring structure, unsaturated ring structure, and combinations thereof; and R 2, R 3, R 4, R 5, R 6 and R 7 are alkyls or silanol-terminated alkyls; and wherein n is an integer, 1 ≤ n ≤ 100; and (b) applying the molecule of formula IV obtained in step (a) to the surface of the medical device.