A system for performing an endoscopic surgical procedure in a surgical cavity of a patient, comprising: a) a multi-lumen tube set including a dual lumen portion having a pressurized gas line and a return gas line for facilitating gas recirculation relative to the surgical cavity of the patient, and a single lumen portion having a gas supply and sensing line for delivering insufflation gas to the surgical cavity of the patient and for periodically sensing pressure within the surgical cavity of the patient, wherein the multi-lumen tube set comprises a multi-path filter cartridge assembly that includes a first filtered flow passage communicating with the pressurized gas line, a second filtered flow passage communicating with the return gas line, and a third filtered flow passage communicating with the gas supply and sensing line; b) a first access port having a proximal housing portion and an elongated single lumen tubular body portion extending distally from the proximal housing portion and defining a central cannula, the proximal housing portion of the first access port having an inlet path for communicating with the pressurized gas line of the tube set and an outlet path for communicating with the return gas line of the tube set, wherein the proximal housing portion of the first access port includes a manifold that defines the inlet path and the outlet path, wherein the inlet and outlet paths (56, 58) are concentrically arranged within the manifold; and c) a second access port having a proximal housing and a single lumen tubular body portion extending from the proximal housing portion of the second access port, the proximal housing portion of the second access port having a mechanical valve for sealing the tubular body portion and an inlet path for communicating with the gas supply and sensing line of the tube set. a) a multi-lumen tube set including a dual lumen portion having a pressurized gas line and a return gas line for facilitating gas recirculation relative to the surgical cavity of the patient, and a single lumen portion having a gas supply and sensing line for delivering insufflation gas to the surgical cavity of the patient and for periodically sensing pressure within the surgical cavity of the patient, wherein the multi-lumen tube set comprises a multi-path filter cartridge assembly that includes a first filtered flow passage communicating with the pressurized gas line, a second filtered flow passage communicating with the return gas line, and a third filtered flow passage communicating with the gas supply and sensing line; b) a first access port having a proximal housing portion and an elongated single lumen tubular body portion extending distally from the proximal housing portion and defining a central cannula, the proximal housing portion of the first access port having an inlet path for communicating with the pressurized gas line of the tube set and an outlet path for communicating with the return gas line of the tube set, wherein the proximal housing portion of the first access port includes a manifold that defines the inlet path and the outlet path, wherein the inlet and outlet paths (56, 58) are concentrically arranged within the manifold; and c) a second access port having a proximal housing and a single lumen tubular body portion extending from the proximal housing portion of the second access port, the proximal housing portion of the second access port having a mechanical valve for sealing the tubular body portion and an inlet path for communicating with the gas supply and sensing line of the tube set.