mhurhangee/ep-ind-claims huggingface dataset:
A compound for use in the treatment of tumors by enhancing the antitumor effect of an antitumor agent in a patient, wherein the compound has plasminogen activator inhibitor-1 (PAI-1) inhibitory activity and the compound is represented by Formula below or a pharmacologically acceptable salt thereof: wherein - either R 1 or R 2 is hydrogen, and the other is halogen; - X is vinylene (-CH=CH-); and - A is a group represented by Formula (I-1) below: wherein - q is an integer of 1; - both R 3 and R 4 are hydrogen; - T is a single bond; - D is aryl which optionally has one or two substituents, benzo-fused heteroaryl which optionally has one or two substituents, or heteroaryl which optionally has one or two substituents, wherein the substituent on heteroaryl is selected from the group of halogen, C 1-6 alkyl, C 3-8 cycloalkyl, C 1-6 alkoxy, C 3-8 cycloalkoxy, C 1-6 halogen-substituted alkoxy, hydroxyl, CF 3, CF 3 O, CHF 2 O, CF 3 CH 2 O, cyano, carboxy, alkoxycarbonyl, benzoyl, phenyl, and phosphonooxymethyl; - L is a single bond, -CONH-, or alkyleneoxyalkylene-CONH-; and - B is COOR 9 [wherein Rg is hydrogen or a group converted to hydrogen in vivo, which is selected from the group consisting of C 1-6 -alkyl, aryl, aralkyl, a group represented by -CH(R 10)-O-CO-R 11 or -CH(R 10)-O-CO-OR 11 (wherein R 10 is C 1-6 -alkyl or C 3-8 -cycloalkyl, and R 11 is C 1-6 -alkyl), and (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl represented by Formula below: wherein R 12 is C 1-6 alkyl]; or a heterocyclic group represented by any of Formulae to below: in the heterocyclic group represented by Formula above, Z represents sulfur or oxygen]. - either R 1 or R 2 is hydrogen, and the other is halogen; - X is vinylene (-CH=CH-); and - A is a group represented by Formula (I-1) below: - q is an integer of 1; - both R 3 and R 4 are hydrogen; - T is a single bond; - D is aryl which optionally has one or two substituents, benzo-fused heteroaryl which optionally has one or two substituents, or heteroaryl which optionally has one or two substituents, wherein the substituent on heteroaryl is selected from the group of halogen, C 1-6 alkyl, C 3-8 cycloalkyl, C 1-6 alkoxy, C 3-8 cycloalkoxy, C 1-6 halogen-substituted alkoxy, hydroxyl, CF 3, CF 3 O, CHF 2 O, CF 3 CH 2 O, cyano, carboxy, alkoxycarbonyl, benzoyl, phenyl, and phosphonooxymethyl; - L is a single bond, -CONH-, or alkyleneoxyalkylene-CONH-; and - B is COOR 9 [wherein Rg is hydrogen or a group converted to hydrogen in vivo, which is selected from the group consisting of C 1-6 -alkyl, aryl, aralkyl, a group represented by -CH(R 10)-O-CO-R 11 or -CH(R 10)-O-CO-OR 11 (wherein R 10 is C 1-6 -alkyl or C 3-8 -cycloalkyl, and R 11 is C 1-6 -alkyl), and (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl represented by Formula below: wherein R 12 is C 1-6 alkyl]; or a heterocyclic group represented by any of Formulae to below: in the heterocyclic group represented by Formula above, Z represents sulfur or oxygen].
A display device or portable terminal (1000, 1001), comprising: a window member comprising a flat portion and a bent portion (BA1, BA2) connected to the flat portion; a display panel (200, 201) disposed on a rear surface of the window member and comprising a central portion and a corner portion protruding from the central portion and overlapping with the flat portion and the bent portion (BA1, BA2); a first sealing member (SM1, SM11) disposed on a rear surface of the display panel (200, 201) and overlapping with the corner portion; a second sealing member (SM2, SM12) disposed on the rear surface of the window member and spaced apart from the central portion and the corner portion; a first adhesive (AD1, AD11) contacting the first sealing member (SM1, SM11) and the second sealing member (SM2, SM12) and sealing a space which is defined between the first sealing member (SM1, SM11) and the second sealing member (SM2, SM12) in the flat portion. a window member comprising a flat portion and a bent portion (BA1, BA2) connected to the flat portion; a display panel (200, 201) disposed on a rear surface of the window member and comprising a central portion and a corner portion protruding from the central portion and overlapping with the flat portion and the bent portion (BA1, BA2); a first sealing member (SM1, SM11) disposed on a rear surface of the display panel (200, 201) and overlapping with the corner portion; a second sealing member (SM2, SM12) disposed on the rear surface of the window member and spaced apart from the central portion and the corner portion; a first adhesive (AD1, AD11) contacting the first sealing member (SM1, SM11) and the second sealing member (SM2, SM12) and sealing a space which is defined between the first sealing member (SM1, SM11) and the second sealing member (SM2, SM12) in the flat portion.
A method for producing a micro- or nano-structured molded part, comprising the steps of (a) providing an intermediate mold insert comprising a support structure, wherein the intermediate mold insert comprises a shape memory material at least in sections, (b) forming a micro- or nano-structured surface on the intermediate mold insert, so that the intermediate mold insert comprises a support structure and a micro- or nano-structured surface formed on the support structure, (c') reshaping the intermediate mold insert to a free-form mold insert for producing a micro- or nano-structured molded part by reshaping the support structure to a three-dimensionally deformed free form F D at least in sections, (d) shaping the micro- or nano-structured molded part by means of the free-form mold insert, (e) at least partially demolding the micro- or nano-structured mold part by restoring the permanent shape F 0 of the intermediate mold insert by activation of the shape memory material. (a) providing an intermediate mold insert comprising a support structure, wherein the intermediate mold insert comprises a shape memory material at least in sections, (b) forming a micro- or nano-structured surface on the intermediate mold insert, so that the intermediate mold insert comprises a support structure and a micro- or nano-structured surface formed on the support structure, (c') reshaping the intermediate mold insert to a free-form mold insert for producing a micro- or nano-structured molded part by reshaping the support structure to a three-dimensionally deformed free form F D at least in sections, (d) shaping the micro- or nano-structured molded part by means of the free-form mold insert, (e) at least partially demolding the micro- or nano-structured mold part by restoring the permanent shape F 0 of the intermediate mold insert by activation of the shape memory material.
A system for assessing effective delivery of ablation therapy to a tissue in a body, comprising: an electronic control unit configured to generate a three-dimensional anatomical map (72, 80) of said tissue, said map defining a corresponding volume; and a display configured to display said anatomical map; wherein said electronic control unit is further configured to: receive a user input; adjust at least one weight responsive to the user input; apply each adjusted weight to a plurality of associated factors indicative of delivery of ablation therapy at a first location (76, 84) within said volume to create a plurality of weighted factors, wherein an adjusted weight applied to one associated factor is different than an adjusted weight applied to another associated factor, update a cumulative index indicating a state of the ablation therapy at the first location (76, 84) based upon said at least one weighted factor; and alter, responsive to said updated cumulative index, a visual characteristic of a portion of said anatomical map corresponding to said first location (76, 84). an electronic control unit configured to generate a three-dimensional anatomical map (72, 80) of said tissue, said map defining a corresponding volume; and a display configured to display said anatomical map; wherein said electronic control unit is further configured to: receive a user input; adjust at least one weight responsive to the user input; apply each adjusted weight to a plurality of associated factors indicative of delivery of ablation therapy at a first location (76, 84) within said volume to create a plurality of weighted factors, wherein an adjusted weight applied to one associated factor is different than an adjusted weight applied to another associated factor, update a cumulative index indicating a state of the ablation therapy at the first location (76, 84) based upon said at least one weighted factor; and alter, responsive to said updated cumulative index, a visual characteristic of a portion of said anatomical map corresponding to said first location (76, 84). receive a user input; adjust at least one weight responsive to the user input; apply each adjusted weight to a plurality of associated factors indicative of delivery of ablation therapy at a first location (76, 84) within said volume to create a plurality of weighted factors, wherein an adjusted weight applied to one associated factor is different than an adjusted weight applied to another associated factor, update a cumulative index indicating a state of the ablation therapy at the first location (76, 84) based upon said at least one weighted factor; and alter, responsive to said updated cumulative index, a visual characteristic of a portion of said anatomical map corresponding to said first location (76, 84).
A method, comprising at a user equipment: receiving a set of candidate grants, wherein the receiving comprises performing blind decoding with respect to an associated control channel; and identifying the set of candidate grants based on the blind decoding; discarding respective received candidate grants deemed to be invalid based on at least one criterion, thereby resulting in remaining candidate grants; and selecting candidate grants intended for the user equipment from among the remaining candidate grants. receiving a set of candidate grants, wherein the receiving comprises performing blind decoding with respect to an associated control channel; and identifying the set of candidate grants based on the blind decoding; performing blind decoding with respect to an associated control channel; and identifying the set of candidate grants based on the blind decoding; discarding respective received candidate grants deemed to be invalid based on at least one criterion, thereby resulting in remaining candidate grants; and selecting candidate grants intended for the user equipment from among the remaining candidate grants.
A system, for point of sale, the system being operable in an indicia reading mode and a verification mode, the system comprising: an illumination subsystem configured to illuminate items with radiation from light sources, wherein the radiation depends upon the operating mode; an imaging subsystem configured to acquire images of an indicia or an item illuminated by the illumination system; an indicia-reading subsystem configured to decode indicia information from images acquired by the imaging subsystem when the system is in the indicia reading mode; and a verification subsystem configured to: verify items from images acquired by the imaging subsystem when the system is in the verification mode; and produce an output corresponding to the verification, so that the output is configured to restrict the checkout process in case of failed verification; wherein when the system is in indicia reading mode, the system switches from the indicia reading mode to the verification mode in response to decoded indicia information indicating that verification is necessary. an illumination subsystem configured to illuminate items with radiation from light sources, wherein the radiation depends upon the operating mode; an imaging subsystem configured to acquire images of an indicia or an item illuminated by the illumination system; an indicia-reading subsystem configured to decode indicia information from images acquired by the imaging subsystem when the system is in the indicia reading mode; and a verification subsystem configured to: verify items from images acquired by the imaging subsystem when the system is in the verification mode; and produce an output corresponding to the verification, so that the output is configured to restrict the checkout process in case of failed verification; wherein when the system is in indicia reading mode, the system switches from the indicia reading mode to the verification mode in response to decoded indicia information indicating that verification is necessary. verify items from images acquired by the imaging subsystem when the system is in the verification mode; and produce an output corresponding to the verification, so that the output is configured to restrict the checkout process in case of failed verification; wherein when the system is in indicia reading mode, the system switches from the indicia reading mode to the verification mode in response to decoded indicia information indicating that verification is necessary.
A ferrule assembly comprising: a receptacle ferrule for a fiber optic receptacle connector for mating with a fiber optic plug connector having a plug ferrule with a plug optical pathway, the receptacle ferrule comprising: a receptacle ferrule body having top and bottom surfaces (371, 373) and opposite back and front ends (372, 374); at least one monolithic optical system formed in receptacle ferrule body and including a lens formed at the bottom surface and a mirror formed at the back end, the at least one monolithic optical system being configured to define a receptacle optical pathway from the bottom surface to the front end and having a substantially right-angle bend; and a plug ferrule matingly engaged to the receptacle ferrule; wherein the front end of the receptacle ferrule body has a first mating geometry configured to form with the plug ferrule a solid-solid contact at an interface between the plug and receptacle optical pathways (450P, 450R), with the solid-solid contact being sufficient to substantially expel liquid from the interface. a receptacle ferrule for a fiber optic receptacle connector for mating with a fiber optic plug connector having a plug ferrule with a plug optical pathway, the receptacle ferrule comprising: a receptacle ferrule body having top and bottom surfaces (371, 373) and opposite back and front ends (372, 374); at least one monolithic optical system formed in receptacle ferrule body and including a lens formed at the bottom surface and a mirror formed at the back end, the at least one monolithic optical system being configured to define a receptacle optical pathway from the bottom surface to the front end and having a substantially right-angle bend; and a receptacle ferrule body having top and bottom surfaces (371, 373) and opposite back and front ends (372, 374); at least one monolithic optical system formed in receptacle ferrule body and including a lens formed at the bottom surface and a mirror formed at the back end, the at least one monolithic optical system being configured to define a receptacle optical pathway from the bottom surface to the front end and having a substantially right-angle bend; and a plug ferrule matingly engaged to the receptacle ferrule;
Length or position measuring system which has an at least locally substantially linear measuring gauge (400, 405) and at least one sensor that is able to be moved relative to the measuring gauge (400, 405), wherein the measuring gauge (400, 405) comprises an incremental track and at least one absolute track and wherein the incremental track and the at least one absolute track have poles arranged in the longitudinal direction of the measuring gauge (400, 405), characterised in that the poles of the at least one absolute track are divided in at least four pole segments, wherein the at least one absolute track provides a mixture of poles of different polarity, by means of which at least five logical values are generated, wherein the logical values of pole pairs (410, 415, 420, 425, 430) provided by the absolute track are formed from completely opposed, over partially opposed, over neutral, over partially concordant and completely concordant compared to the corresponding pole pairs (410, 415, 420, 425, 430) of the incremental track, whereby the at least five logical values +1, +0.5, 0, -0.5 and -1 are generated.
A molten metal pump comprised of a base defining a pumping chamber, an impeller disposed within said pumping chamber, an outlet passage extending from said pumping chamber, said outlet passage being defined by opposed top and bottom walls and opposed side walls (124, 124'), that are elements of the base, wherein at least one of said top wall and said opposed side walls (124, 124') include a gas injection inlet, and wherein said top and side walls (124, 124') terminate at an intersection with a boundary of the base, said boundary defining an exit from the outlet passage, and wherein at least a portion of said bottom wall terminates inward from said boundary.
A polysiloxane composition comprising polysiloxane and a hydroxyalkylsilane having a boiling point of at least 80 °C at a pressure of up to 1 mbar and having no side groups attached to the silicon atom(s) that are capable of undergoing hydrolysis or condensation under curing conditions.
A thermal-acoustic section (36, 236, 336, 436) for an aircraft for reducing noise along an acoustic path produced from an acoustic source, the thermal-acoustic section (36, 236, 336, 436) comprising: a first porous layer (351, 451) having a first characteristic acoustic impedance; and a second porous layer (352, 452) disposed adjacent to the first porous layer (351, 451) and having a second characteristic acoustic impedance that is greater than the first characteristic acoustic impedance, wherein the thermal-acoustic section (36, 236, 336, 436) is configured to be positioned along the acoustic path such that at least a portion of the noise is directed through the first porous layer (351, 451) to the second porous layer (352, 452) to promote absorption of the noise, wherein the first porous layer (351, 451) is in a first compressed condition at a first percent compression such that the first porous layer (351, 451) has a first acoustic absorption coefficient that is about 95% or greater of a maximum acoustic absorption value for the first porous layer over a predetermined frequency range; and/or wherein the second porous layer (352, 452) is in a second compressed condition at a second percent compression such that the second porous layer (352, 452) has a second acoustic absorption coefficient that is about 95% or greater of a maximum acoustic absorption value for the second porous layer (352, 452) over a predetermined frequency range. a first porous layer (351, 451) having a first characteristic acoustic impedance; and a second porous layer (352, 452) disposed adjacent to the first porous layer (351, 451) and having a second characteristic acoustic impedance that is greater than the first characteristic acoustic impedance, wherein the thermal-acoustic section (36, 236, 336, 436) is configured to be positioned along the acoustic path such that at least a portion of the noise is directed through the first porous layer (351, 451) to the second porous layer (352, 452) to promote absorption of the noise, wherein the first porous layer (351, 451) is in a first compressed condition at a first percent compression such that the first porous layer (351, 451) has a first acoustic absorption coefficient that is about 95% or greater of a maximum acoustic absorption value for the first porous layer over a predetermined frequency range; and/or wherein the second porous layer (352, 452) is in a second compressed condition at a second percent compression such that the second porous layer (352, 452) has a second acoustic absorption coefficient that is about 95% or greater of a maximum acoustic absorption value for the second porous layer (352, 452) over a predetermined frequency range.
A coupling arrangement for fluid coupling a work tool to a machine comprising: a plurality of coupler assemblies slideably mounted in a plurality of cavities for coupling a machine fluid circuit and a work tool fluid circuit, the coupler assembles partitioning the cavities to form chambers; a rail circuit connecting the chambers wherein the rail circuit comprises a single hydraulic line connected to each of the chambers through further hydraulic lines; and at least one actuator connected to the rail circuit for actuating the plurality of coupler assemblies between a connect position and a disconnect position. a plurality of coupler assemblies slideably mounted in a plurality of cavities for coupling a machine fluid circuit and a work tool fluid circuit, the coupler assembles partitioning the cavities to form chambers; a rail circuit connecting the chambers wherein the rail circuit comprises a single hydraulic line connected to each of the chambers through further hydraulic lines; and at least one actuator connected to the rail circuit for actuating the plurality of coupler assemblies between a connect position and a disconnect position.
A method for preparing a hydrophobic silica aerogel, the method comprising Soxhlet extracting a hydrophobic silica wet gel, wherein the hydrophobic silica wet gel is a hydrophobic silica lyogel or a hydrophobic silica hydrogel, solvent substitution, washing, and drying are simultaneously performed on the hydrophobic silica wet gel during the Soxhlet extraction, and the Soxhlet extraction is performed in a pressure of 40 bar to 70 bar by using carbon dioxide as an extraction solvent, or in a pressure of 5 bar to 20 bar by using dimethyl ether as an extraction solvent.
Cylinder lubricant having a BN determined according to standard ASTM D-2896 greater than or equal to 15, preferably greater than 20, preferably greater than 30, advantageously greater than 40 milligrams of potash per gram of lubricant, comprising: a) one or more lubricating base oils for marine engines, b) at least one detergent based on alkali or alkaline-earth metals, overbased with metallic carbonate salts, optionally in combination with one or more neutral detergents, c) one or more oil-soluble fatty amines having a BN determined according to standard ASTM D-2896 comprised between 150 and 600 milligrams of potash per gram, preferably comprised between 200 and 500 milligrams of potash per gram, the percentage by mass of fatty amines relative to the total weight of lubricant being chosen such that the BN provided by these compounds represents a contribution of at least 10 milligrams of potash per gram of lubricant, preferably at least 20 milligrams of potash per gram, preferably at least 30 milligrams of potash per gram, still more preferably at least 40 milligrams of potash per gram of lubricant, to the total BN of said cylinder lubricant, the percentage by mass of overbased detergents relative to the total weight of lubricant being chosen such that the BN provided by the metallic carbonate salts represents a contribution of at most 20 milligrams of potash per gram of lubricant to the total BN of said cylinder lubricant, and the fatty amine comprises at least one aliphatic chain made up of at least 16 carbon atoms. a) one or more lubricating base oils for marine engines, b) at least one detergent based on alkali or alkaline-earth metals, overbased with metallic carbonate salts, optionally in combination with one or more neutral detergents, c) one or more oil-soluble fatty amines having a BN determined according to standard ASTM D-2896 comprised between 150 and 600 milligrams of potash per gram, preferably comprised between 200 and 500 milligrams of potash per gram,