mhurhangee/ep-ind-claims huggingface dataset:
A mounting tool for mounting a flexible ring-shaped part of an anastomotic device on a rigid part of an anastomotic device, said tool comprising: a receiving portion in a distal end of the mounting tool for receiving the flexible part thereat; a handle portion proximally of said receiving portion; said receiving portion comprises an elongated tubular sheet element, and a tubular displacement element, arranged within the sheet element to be longitudinally displaceable in relation to the sheet element, such that a shelf is obtained circumferentially of the tubular displacement element and distally of the sheet element, said shelf being configured to receive the flexible part, the mounting tool further comprising a tubular cutting element inside the tubular displacement element, such that the tubular cutting element is longitudinally displaceable within and in relation to the tubular displacement element, and said mounting tool being characterized in that the tubular sheet element or the tubular cutting element is spring loaded proximally of the receiving portion, such that a release of the spring load will move the sheet element or the cutting element distally in relation to the displacement element. a receiving portion in a distal end of the mounting tool for receiving the flexible part thereat; a handle portion proximally of said receiving portion; said receiving portion comprises an elongated tubular sheet element, and a tubular displacement element, arranged within the sheet element to be longitudinally displaceable in relation to the sheet element, such that a shelf is obtained circumferentially of the tubular displacement element and distally of the sheet element, said shelf being configured to receive the flexible part, the mounting tool further comprising a tubular cutting element inside the tubular displacement element, such that the tubular cutting element is longitudinally displaceable within and in relation to the tubular displacement element, and said mounting tool being characterized in that the tubular sheet element or the tubular cutting element is spring loaded proximally of the receiving portion, such that a release of the spring load will move the sheet element or the cutting element distally in relation to the displacement element.
A tourniquet comprising: • a support capable of surrounding a first part of a limb, • an elastic sleeve capable of being held in a stretched position around the support, the support preventing a contraction of the elastic sleeve, • a grip element movable with respect to the support, • a drive element capable of driving the elastic sleeve, when the grip element is manually displaced with respect to the support, from its stretched position around the support to a constricting position in which the elastic sleeve surrounds a second part of the limb, adjacent to the first part of the limb but not surrounded by the support, so that the elastic sleeve can retract itself by elastic return, and thus compress the second part of the limb, characterized in that the drive element comprises a first portion and is capable of adopting: • a folded configuration wherein the first portion extends between the support and the elastic sleeve in its entirety maintained in the stretched position around the support, • a deployed configuration wherein the elastic sleeve, in the constricting position, extends between the first portion and the second part of the limb when the support surrounds the first part of the limb, and in that the grip element is arranged with respect to the first portion so that a displacement of the grip element with respect to the support causes the first portion of the drive element to shift from the folded configuration to the deployed configuration so as to displace, by lever action, the elastic sleeve from the stretched position to the constricting position. • a support capable of surrounding a first part of a limb, • an elastic sleeve capable of being held in a stretched position around the support, the support preventing a contraction of the elastic sleeve, • a grip element movable with respect to the support, • a drive element capable of driving the elastic sleeve, when the grip element is manually displaced with respect to the support, from its stretched position around the support to a constricting position in which the elastic sleeve surrounds a second part of the limb, adjacent to the first part of the limb but not surrounded by the support, so that the elastic sleeve can retract itself by elastic return, and thus compress the second part of the limb, • a folded configuration wherein the first portion extends between the support and the elastic sleeve in its entirety maintained in the stretched position around the support, • a deployed configuration wherein the elastic sleeve, in the constricting position, extends between the first portion and the second part of the limb when the support surrounds the first part of the limb, and in that the grip element is arranged with respect to the first portion so that a displacement of the grip element with respect to the support causes the first portion of the drive element to shift from the folded configuration to the deployed configuration so as to displace, by lever action, the elastic sleeve from the stretched position to the constricting position.
Mounted turn-about plow having a mounting pedestal for being mounted on a tractor, a plow frame which is rotatable about a horizontal turning axis, having plow bodies pivotally arranged thereon, the plow bodies being pivotally adjustable in terms of their working width by means of a cutting width actuator, and the plow frame being mounted on a turning bracket, which is rotatably mounted on the mounting pedestal about the horizontal turning axis, so that said frame can be pivoted about a pivot axis arranged transversely to the turning axis and the frame being pivotable into a turning position with reduced transverse extension by means of a pivot actuator for the turning process, the pivot actuator being controllable by means of a frame pivot controller for different pre-settings in different lift positions to reach the turning position, the frame pivot controller comprising a limiting device for starting and holding the turning position, characterized in that the frame pivot controller has a detection device for detecting the lift position of the cutting width actuator, and in that the frame pivot controller is designed to limit the lift adjustment path of the pivot actuator to the lift position for the turning position by means of the limiting device depending on the detected lift position of the cutting width actuator.
A juicer for extracting juice from food ingredients comprising: a cavity for receiving the food ingredients, the cavity having an outlet which is adapted to be opened and closed; a tool in the cavity for releasing juice from the food ingredients; a rotary sieve for receiving food ingredients processed by the tool from the cavity outlet, the rotary sieve having an outer sieve wall; a drive system for operating the tool to cut the food ingredients in the cavity, and for rotating the rotary sieve so as to pass juice through the outer sieve wall wherein the drive system enables independent control of the tool and the rotating of the sieve; and a juice outlet for providing juice which has passed through the outer sieve wall. a cavity for receiving the food ingredients, the cavity having an outlet which is adapted to be opened and closed; a tool in the cavity for releasing juice from the food ingredients; a rotary sieve for receiving food ingredients processed by the tool from the cavity outlet, the rotary sieve having an outer sieve wall; a drive system for operating the tool to cut the food ingredients in the cavity, and for rotating the rotary sieve so as to pass juice through the outer sieve wall wherein the drive system enables independent control of the tool and the rotating of the sieve; and a juice outlet for providing juice which has passed through the outer sieve wall.
A gas turbine engine comprising: a core casing; and a fairing (10, 101) coupled to the core casing to cover the core casing, the fairing comprising a first layer comprising a metallic material and defining a first surface and a second opposite surface, the first layer being coupled to the core casing of the gas turbine engine; and a second layer comprising a composite material and defining a first surface and a second opposite surface, the second layer being coupled to the first layer, the second surface of the second layer defining an external surface of the fairing. a core casing; and a fairing (10, 101) coupled to the core casing to cover the core casing, the fairing comprising a first layer comprising a metallic material and defining a first surface and a second opposite surface, the first layer being coupled to the core casing of the gas turbine engine; and a second layer comprising a composite material and defining a first surface and a second opposite surface, the second layer being coupled to the first layer, the second surface of the second layer defining an external surface of the fairing.
A polysiloxane-polycarbonate copolymer comprising: as repeating units, a hydroxyl-terminated polysiloxane of the following chemical formula 1; a hydroxyl-terminated polysiloxane of the following chemical formula 2; and a polycarbonate block; wherein total 100 parts by weight of the hydroxyl-terminated polysiloxanes of chemical formulas 1 and 2 consists of 1 to 39 parts by weight of the hydroxyl-terminated polysiloxane of chemical formula 1 and 61 to 99 parts by weight of the hydroxyl-terminated polysiloxane of chemical formula 2: wherein: in the above chemical formulas 1 and 2, each R 1 independently represents hydrogen atom, halogen atom, hydroxy group, an alkyl group, an alkoxy group, or an aryl group; each R 2 independently represents a hydrocarbon group having 1 to 13 carbon atoms, or hydroxy group; each R 3 independently represents an alkylene group having 2 to 8 carbon atoms; A represents a substituted or unsubstituted divalent hydrocarbon group comprising one or more bonds selected from ester bond, ether bond, thioether bond, ketone bond or urethane bond; l represents an integer of 0 to 4; and each of m and n independently represents an integer of 2 to 1,000. as repeating units, a hydroxyl-terminated polysiloxane of the following chemical formula 1; a hydroxyl-terminated polysiloxane of the following chemical formula 2; and a polycarbonate block; wherein total 100 parts by weight of the hydroxyl-terminated polysiloxanes of chemical formulas 1 and 2 consists of 1 to 39 parts by weight of the hydroxyl-terminated polysiloxane of chemical formula 1 and 61 to 99 parts by weight of the hydroxyl-terminated polysiloxane of chemical formula 2: wherein: in the above chemical formulas 1 and 2, each R 1 independently represents hydrogen atom, halogen atom, hydroxy group, an alkyl group, an alkoxy group, or an aryl group; each R 2 independently represents a hydrocarbon group having 1 to 13 carbon atoms, or hydroxy group; each R 3 independently represents an alkylene group having 2 to 8 carbon atoms; A represents a substituted or unsubstituted divalent hydrocarbon group comprising one or more bonds selected from ester bond, ether bond, thioether bond, ketone bond or urethane bond; l represents an integer of 0 to 4; and each of m and n independently represents an integer of 2 to 1,000.
A mouse with ganglioglioma and brain somatic mutation-related intractable epilepsy, comprising - a mutant nucleic acid molecule, comprising the sequence of SEQ ID NO: 4 in which thymine at position 1910 is substituted to adenine, encoding a BRAF mutant protein consisting of the amino acid sequence of SEQ ID NO: 3 in which valine at position 637 is substituted to glutamic acid, wherein the mouse is induced to express the BRAF mutant protein or the mutant nucleic acid molecule encoding the BRAF mutant protein, in brain during the formation of a cortical layer in embryonic period, and wherein the mouse has an activated MARK signaling pathway of Ras-Raf-MEK-ERK, dysplasia of nerve cells and a numerical increment of glial cells. - a mutant nucleic acid molecule, comprising the sequence of SEQ ID NO: 4 in which thymine at position 1910 is substituted to adenine, encoding a BRAF mutant protein consisting of the amino acid sequence of SEQ ID NO: 3 in which valine at position 637 is substituted to glutamic acid, wherein the mouse is induced to express the BRAF mutant protein or the mutant nucleic acid molecule encoding the BRAF mutant protein, in brain during the formation of a cortical layer in embryonic period, and wherein the mouse has an activated MARK signaling pathway of Ras-Raf-MEK-ERK, dysplasia of nerve cells and a numerical increment of glial cells.
An image processing device for acquiring a plurality of images and for generating a composite image, comprising: a unit for determining a number of combined images, the unit detecting the number of combined images for each area of the composite image generated from a plurality of the combined images and storing the number as information about the number of combined images for each area of the composite image when the composite image is generated; one of or both of an image processing parameter switch unit for switching a parameter of image processing performed on each area of the composite image according to the information about the number of combined images, the parameter being different for different numbers of combined images, and an image processing switch unit for switching to another type of image processing performed on each area of the composite image according to the information about the number of combined images; and a unit for performing image processing on the composite image according to one of or both of the switching result of the image processing parameter switch unit and the switching result of the image processing switch unit. a unit for determining a number of combined images, the unit detecting the number of combined images for each area of the composite image generated from a plurality of the combined images and storing the number as information about the number of combined images for each area of the composite image when the composite image is generated; one of or both of an image processing parameter switch unit for switching a parameter of image processing performed on each area of the composite image according to the information about the number of combined images, the parameter being different for different numbers of combined images, and an image processing switch unit for switching to another type of image processing performed on each area of the composite image according to the information about the number of combined images; and a unit for performing image processing on the composite image according to one of or both of the switching result of the image processing parameter switch unit and the switching result of the image processing switch unit.
A building wall, comprising: a wall body; a rechargeable battery component provided in the wall body, wherein the rechargeable battery component forms a combined structure with the wall body, and is configured to supply power to electrical equipment; a photovoltaic outer wall panel, wherein the wall body comprises an outer wall surface on which the photovoltaic outer wall panel is provided; characterized in that a pre-embedded part is provided in the wall body, wherein the photovoltaic outer wall panel is electrically connected with the rechargeable battery component by the pre-embedded part; wherein the rechargeable battery component is a rechargeable energy storage cement battery component, one end of the pre-embedded part is connected to the photovoltaic outer wall panel, and the other end of the pre-embedded part is connected with the rechargeable energy storage cement battery component. a wall body; a rechargeable battery component provided in the wall body, wherein the rechargeable battery component forms a combined structure with the wall body, and is configured to supply power to electrical equipment; a photovoltaic outer wall panel, wherein the wall body comprises an outer wall surface on which the photovoltaic outer wall panel is provided; characterized in that a pre-embedded part is provided in the wall body, wherein the photovoltaic outer wall panel is electrically connected with the rechargeable battery component by the pre-embedded part; wherein the rechargeable battery component is a rechargeable energy storage cement battery component, one end of the pre-embedded part is connected to the photovoltaic outer wall panel, and the other end of the pre-embedded part is connected with the rechargeable energy storage cement battery component.
A compound of the formula wherein: Cy is heteroaryl or heterocycle, each is substituted by R 1 and optionally substituted by halogen, halo C 1-4 alkyl, C 1-4 alkyl, oxo and C 1-4 alkoxy; R 1 is chosen from: L-Ar, C 1-6 alkyl, -S m -R 3 and C 1-6 alkoxy, each Ar, C 1-6 alkyl and C 1-6 alkoxy are optionally substituted by benzyl, halogen, halo C 1-4 alkyl, C 1-4 alkyl, R 2 -S m -, -CN, - C -N(R 3) 2 or C 1-4 alkoxy; L is a linker chosen from a bond, O, >C, -(CH 2) n -, -O-(CH 2) n -, -N(R 3)-, -N(R 3)-(CH 2) n -, -(CH 2) n -N(R 3)-, -C -N(R 3)-, -C -N(R 3)-(CH 2) n -,-N(R 3)-C -N(R 3)-, -N(R 3)-C -, -S m -N(R 3)-, R 3 -S m -, and -N(R 3)-S m -, wherein the -CH 2 - in each L can have 1-2 hydrogens replaced by C 1-3 alkyl, said C 1-3 alkyl groups can optionally cyclize to form a C 3-6 cycloalkyl ring; Ar is carbocycle, heterocycle or heteroaryl; X of the formula is a nitrogen containing C 6 -C 10 spirocycle, each X is substituted by one R 4 and optionally substituted by halogen, halo C 1-4 alkyl, C 1-4 alkyl and C 1-4 alkoxy; R 4 is each n is independently 1-4; each m is independently 0-2; each R 2 and R 3 are independently chosen from hydrogen or C 1-4 alkyl; each R 5 is independently chosen from hydrogen, halogen, C 1-4 alkyl, C 1-4 alkoxy, C 1-4 alkylC 1-4 alkoxy, C 1-4 alkylhydroxy, -(CH 2) n -heterocycle and heterocycle each heterocycle optionally substituted by halogen, OH or R 2 -S m -; each group defined above for Cy, R 1 -R 5, and Y can be, where possible partially or fully halogenated; or a pharmaceutically acceptable salt thereof. Cy is heteroaryl or heterocycle, each is substituted by R 1 and optionally substituted by halogen, halo C 1-4 alkyl, C 1-4 alkyl, oxo and C 1-4 alkoxy; R 1 is chosen from: L-Ar, C 1-6 alkyl, -S m -R 3 and C 1-6 alkoxy, each Ar, C 1-6 alkyl and C 1-6 alkoxy are optionally substituted by benzyl, halogen, halo C 1-4 alkyl, C 1-4 alkyl, R 2 -S m -, -CN, - C -N(R 3) 2 or C 1-4 alkoxy; L is a linker chosen from a bond, O, >C, -(CH 2) n -, -O-(CH 2) n -, -N(R 3)-, -N(R 3)-(CH 2) n -, -(CH 2) n -N(R 3)-, -C -N(R 3)-, -C -N(R 3)-(CH 2) n -,-N(R 3)-C -N(R 3)-, -N(R 3)-C -, -S m -N(R 3)-, R 3 -S m -, and -N(R 3)-S m -, wherein the -CH 2 - in each L can have 1-2 hydrogens replaced by C 1-3 alkyl, said C 1-3 alkyl groups can optionally cyclize to form a C 3-6 cycloalkyl ring; Ar is carbocycle, heterocycle or heteroaryl; X of the formula is a nitrogen containing C 6 -C 10 spirocycle, each X is substituted by one R 4 and optionally substituted by halogen, halo C 1-4 alkyl, C 1-4 alkyl and C 1-4 alkoxy; R 4 is each n is independently 1-4; each m is independently 0-2; each R 2 and R 3 are independently chosen from hydrogen or C 1-4 alkyl; each R 5 is independently chosen from hydrogen, halogen, C 1-4 alkyl, C 1-4 alkoxy, C 1-4 alkylC 1-4 alkoxy, C 1-4 alkylhydroxy, -(CH 2) n -heterocycle and heterocycle each heterocycle optionally substituted by halogen, OH or R 2 -S m -; each group defined above for Cy, R 1 -R 5, and Y can be, where possible partially or fully halogenated;
Apparatus, comprising: a guidewire having a proximal end and a distal end which is deflectable; at least one wire within the guidewire, traversing the guidewire from the proximal end to the distal end, wherein the at least one wire is fixed to the distal end; one or more irrigation tubes within the guidewire and traversing the guidewire from the proximal end to the distal end; and an imaging assembly enclosure, fixedly attached to the distal end, comprising: a camera, having a distal face, fixedly mounted within the enclosure; respective deflectors for each of the one or more irrigation tubes, fixedly attached to and positioned at a distal end of the enclosure so as to deflect fluid, ejected from the one or more irrigation tubes, to pass over the camera distal face so as to clean the face, so that applying tension at the proximal end of the guidewire on the at least one wire deflects the distal end of the guidewire, the imaging assembly enclosure attached thereto, and the camera in the enclosure; and wherein the one or more irrigation tubes comprises at least two irrigation tubes on opposite sides of the camera, characterised in that j the at least two irrigation tubes are configured to simultaneously eject and withdraw fluid from the camera distal face. a guidewire having a proximal end and a distal end which is deflectable; at least one wire within the guidewire, traversing the guidewire from the proximal end to the distal end, wherein the at least one wire is fixed to the distal end; one or more irrigation tubes within the guidewire and traversing the guidewire from the proximal end to the distal end; and an imaging assembly enclosure, fixedly attached to the distal end, comprising: a camera, having a distal face, fixedly mounted within the enclosure; respective deflectors for each of the one or more irrigation tubes, fixedly attached to and positioned at a distal end of the enclosure so as to deflect fluid, ejected from the one or more irrigation tubes, to pass over the camera distal face so as to clean the face, a camera, having a distal face, fixedly mounted within the enclosure; respective deflectors for each of the one or more irrigation tubes, fixedly attached to and positioned at a distal end of the enclosure so as to deflect fluid, ejected from the one or more irrigation tubes, to pass over the camera distal face so as to clean the face, so that applying tension at the proximal end of the guidewire on the at least one wire deflects the distal end of the guidewire, the imaging assembly enclosure attached thereto, and the camera in the enclosure; and wherein the one or more irrigation tubes comprises at least two irrigation tubes on opposite sides of the camera, characterised in that j the at least two irrigation tubes are configured to simultaneously eject and withdraw fluid from the camera distal face.
A recombinant or chimeric FVIII protein comprising one or more ancestral mutations and a B-domain deletion, and wherein the protein sequence does not naturally occur; and wherein the protein has: an A1 domain having an amino acid sequence having greater than 96% identity to SEQ ID NO: 22, 4, or 13; an A2 domain having an amino acid sequence having greater than 96% identity to SEQ ID NO: 23, 5 or 14; an ap domain having an amino acid sequence having greater than 96% identity to SEQ ID NO: 25, 7, or 16; an A3 domain having an amino acid sequence having greater than 96% identity to SEQ ID NO: 26, 8, or 17; a C1 domain having an amino acid sequence having greater than 96% identity to SEQ ID NO: 27, 9, or 18; and a C2 domain having an amino acid sequence having greater than 96% identity to SEQ ID NO: 28, 10 or 19. an A1 domain having an amino acid sequence having greater than 96% identity to SEQ ID NO: 22, 4, or 13; an A2 domain having an amino acid sequence having greater than 96% identity to SEQ ID NO: 23, 5 or 14; an ap domain having an amino acid sequence having greater than 96% identity to SEQ ID NO: 25, 7, or 16; an A3 domain having an amino acid sequence having greater than 96% identity to SEQ ID NO: 26, 8, or 17; a C1 domain having an amino acid sequence having greater than 96% identity to SEQ ID NO: 27, 9, or 18; and a C2 domain having an amino acid sequence having greater than 96% identity to SEQ ID NO: 28, 10 or 19.