A method for determining an input operation interface of a hand-held terminal, comprising: determining whether a user performs an input operation on the input operation interface of the hand-held terminal, wherein said input operation interface is a touch-screen, by using a right hand or a left hand; if a result of determining is that the user performs the input operation by using the right hand, setting input keys, which are on the input operation interface, to be arranged from right to left according to a preset rule; and if a result of determining is that the user performs the input operation by using the left hand, setting the input keys, which are on the input operation interface, to be arranged from left to right according to the preset rule; characterized in that the determining whether a user performs an input operation on the input operation interface of the hand-held terminal by using a right hand or a left hand comprises: determining on a basis of a probability at which a sub-area of a key is touched, whether the user performs the input operation by using the right hand or the left hand, wherein the key is located on the input operation interface, the sub-area indicates a part on an upper left side, a lower left side, an upper right side, a lower right side, a left side, or a right side of the key, and the probability at which the sub-area of the key is touched indicates a proportion of a quantity of times the sub-area is touched in a total quantity of times the key is touched. determining whether a user performs an input operation on the input operation interface of the hand-held terminal, wherein said input operation interface is a touch-screen, by using a right hand or a left hand; if a result of determining is that the user performs the input operation by using the right hand, setting input keys, which are on the input operation interface, to be arranged from right to left according to a preset rule; and if a result of determining is that the user performs the input operation by using the left hand, setting the input keys, which are on the input operation interface, to be arranged from left to right according to the preset rule; characterized in that the determining whether a user performs an input operation on the input operation interface of the hand-held terminal by using a right hand or a left hand comprises: determining on a basis of a probability at which a sub-area of a key is touched, whether the user performs the input operation by using the right hand or the left hand, wherein the key is located on the input operation interface, the sub-area indicates a part on an upper left side, a lower left side, an upper right side, a lower right side, a left side, or a right side of the key, and the probability at which the sub-area of the key is touched indicates a proportion of a quantity of times the sub-area is touched in a total quantity of times the key is touched. determining on a basis of a probability at which a sub-area of a key is touched, whether the user performs the input operation by using the right hand or the left hand, wherein the key is located on the input operation interface, the sub-area indicates a part on an upper left side, a lower left side, an upper right side, a lower right side, a left side, or a right side of the key, and the probability at which the sub-area of the key is touched indicates a proportion of a quantity of times the sub-area is touched in a total quantity of times the key is touched.