An end effector for a surgical clip applier, comprising: a housing having a tapered section at a distal end thereof; first and second jaw members protruding distally from the tapered section; a surgical clip feeder arranged within the housing and configured to contain a plurality of surgical clips (1510a-f) therein; wherein the plurality of surgical clips are arrangeable within the surgical clip feeder at a non-zero angle with respect to a longitudinal axis of the end effector; and a feedbar longitudinally movable between the housing and the plurality of surgical clips, the feedbar having a distal portion engageable with a distal-most surgical clip of the plurality of surgical clips within the tapered section; wherein actuation of the feedbar engages and advances the distal-most surgical clip out of the surgical clip feeder and into interposition between the first and second jaw members, characterized in that the surgical clip feeder is a first surgical clip feeder positioned in a first hemisphere of the housing, the plurality of surgical clips is a first plurality of surgical clips (1510a-f), and the feedbar is a first feedbar, the end effector further comprising: a second surgical clip feeder positioned in a second hemisphere of the housing opposite the first hemisphere and configured to contain a second plurality of surgical clips (1510b-f) therein; wherein the second plurality of surgical clips are arrangeable within the second surgical clip feeder at a non-zero angle with respect to the longitudinal axis of the end effector; and a second feedbar longitudinally movable between the housing and the second plurality of surgical clips, the second feedbar having a distal portion engageable with a distal-most surgical clip of the second plurality of surgical clips within the tapered section; wherein actuation of the second feedbar engages and advances the distal-most surgical clip out of the second surgical clip feeder and into interposition between the first and second jaw members. a housing having a tapered section at a distal end thereof; first and second jaw members protruding distally from the tapered section; a surgical clip feeder arranged within the housing and configured to contain a plurality of surgical clips (1510a-f) therein; wherein the plurality of surgical clips are arrangeable within the surgical clip feeder at a non-zero angle with respect to a longitudinal axis of the end effector; and a feedbar longitudinally movable between the housing and the plurality of surgical clips, the feedbar having a distal portion engageable with a distal-most surgical clip of the plurality of surgical clips within the tapered section; wherein actuation of the feedbar engages and advances the distal-most surgical clip out of the surgical clip feeder and into interposition between the first and second jaw members, characterized in that the surgical clip feeder is a first surgical clip feeder positioned in a first hemisphere of the housing, the plurality of surgical clips is a first plurality of surgical clips (1510a-f), and the feedbar is a first feedbar, the end effector further comprising: a second surgical clip feeder positioned in a second hemisphere of the housing opposite the first hemisphere and configured to contain a second plurality of surgical clips (1510b-f) therein; wherein the second plurality of surgical clips are arrangeable within the second surgical clip feeder at a non-zero angle with respect to the longitudinal axis of the end effector; and a second feedbar longitudinally movable between the housing and the second plurality of surgical clips, the second feedbar having a distal portion engageable with a distal-most surgical clip of the second plurality of surgical clips within the tapered section; wherein actuation of the second feedbar engages and advances the distal-most surgical clip out of the second surgical clip feeder and into interposition between the first and second jaw members. a second surgical clip feeder positioned in a second hemisphere of the housing opposite the first hemisphere and configured to contain a second plurality of surgical clips (1510b-f) therein; wherein the second plurality of surgical clips are arrangeable within the second surgical clip feeder at a non-zero angle with respect to the longitudinal axis of the end effector; and a second feedbar longitudinally movable between the housing and the second plurality of surgical clips, the second feedbar having a distal portion engageable with a distal-most surgical clip of the second plurality of surgical clips within the tapered section; wherein actuation of the second feedbar engages and advances the distal-most surgical clip out of the second surgical clip feeder and into interposition between the first and second jaw members.