A method of forming an oral care implement comprising a base structure having a handle portion and a head portion, the method comprising: a) providing a first mold that defines a first mold cavity, the first mold cavity comprising a first portion that corresponds to the handle portion of the base structure and a second portion that corresponds to the head portion of the base structure; b) injecting a first material into the first portion of the first mold cavity via a first injection orifice with a first hot runner sub-system, the first injection orifice forming a first passageway into the first portion of the first mold cavity, wherein the first material is transparent or translucent; and c) injecting a second material into the first portion of the first mold cavity via a second injection orifice with a second hot runner sub-system, the second injection orifice forming a second passageway into the first portion of the first mold cavity, the second material being injected into the first material to displace the first material, thereby forming the base structure such that the second material forms a core component of the base structure and the first material forms a shell component of the base structure that surrounds the core component; wherein a portion of an exposed outer surface of the handle portion of the base structure that is aligned with the second injection orifice is formed of the second material, a remainder of the exposed outer surface of the base structure being formed of the first material; the method further comprising: d) cooling the first and second materials (124, 134) in the first mold cavity to harden the base structure; e) placing the base structure in a second mold cavity that is defined by a second mold; and f) injecting a third material into the second mold cavity to cover a portion of the exposed outer surface of the handle portion of the base structure that is formed of the second material to form an elastomeric overmold. a) providing a first mold that defines a first mold cavity, the first mold cavity comprising a first portion that corresponds to the handle portion of the base structure and a second portion that corresponds to the head portion of the base structure; b) injecting a first material into the first portion of the first mold cavity via a first injection orifice with a first hot runner sub-system, the first injection orifice forming a first passageway into the first portion of the first mold cavity, wherein the first material is transparent or translucent; and c) injecting a second material into the first portion of the first mold cavity via a second injection orifice with a second hot runner sub-system, the second injection orifice forming a second passageway into the first portion of the first mold cavity, the second material being injected into the first material to displace the first material, thereby forming the base structure such that the second material forms a core component of the base structure and the first material forms a shell component of the base structure that surrounds the core component; wherein a portion of an exposed outer surface of the handle portion of the base structure that is aligned with the second injection orifice is formed of the second material, a remainder of the exposed outer surface of the base structure being formed of the first material; the method further comprising: d) cooling the first and second materials (124, 134) in the first mold cavity to harden the base structure; e) placing the base structure in a second mold cavity that is defined by a second mold; and f) injecting a third material into the second mold cavity to cover a portion of the exposed outer surface of the handle portion of the base structure that is formed of the second material to form an elastomeric overmold. d) cooling the first and second materials (124, 134) in the first mold cavity to harden the base structure; e) placing the base structure in a second mold cavity that is defined by a second mold; and f) injecting a third material into the second mold cavity to cover a portion of the exposed outer surface of the handle portion of the base structure that is formed of the second material to form an elastomeric overmold.