An actuation structure of a blood vessel clip applier driven by an operating unit to make a jaw clamp a clip, the actuation structure of the blood vessel clip applier comprising: a body comprising a bump; a tube set comprising a rear end connected to said body and a front end comprising the jaw; a loading push rod movably set in said tube set back and forth for pushing said clip forward to the front end of the tube set; a bolt axially movably arranged on said body; a loading plug set in said body to link said loading push rod; characterized in that the actuation structure further comprises: a feeding loop claw pivoted to said bolt, said feeding loop claw comprising a front end and a rear end so configured that when said feeding loop claw moves forward in the direction of the rear end of the tube set, said feeding loop claw is touched by said bump of said body so that the front end of said feeding loop claw changes from a tilted out position to a pressed down position; a loading spring to push said loading plug to move backward in the direction of the rear end of the tube set; wherein when the front end of said feeding loop claw is tilted out, said loading plug is pushed forward in the direction of the front end of the tube set; wherein when the front end of said feeding loop claw is pressed down the front end is kept away from said loading plug, so that said loading spring pushes said loading plug back to its original position; a recoil push rod movably set in said tube set, so that after said loading plug returns to its original position, the front end of said feeding loop claw is still pressed down to push said recoil push rod forward in the direction of the front end of the tube set to drive said jaw clamp said clip; and a recoil spring used to push said recoil push rod to move backward in a direction of the rear end of the the tube set. a body comprising a bump; a tube set comprising a rear end connected to said body and a front end comprising the jaw; a loading push rod movably set in said tube set back and forth for pushing said clip forward to the front end of the tube set; a bolt axially movably arranged on said body; a loading plug set in said body to link said loading push rod; characterized in that the actuation structure further comprises: a feeding loop claw pivoted to said bolt, said feeding loop claw comprising a front end and a rear end so configured that when said feeding loop claw moves forward in the direction of the rear end of the tube set, said feeding loop claw is touched by said bump of said body so that the front end of said feeding loop claw changes from a tilted out position to a pressed down position; a loading spring to push said loading plug to move backward in the direction of the rear end of the tube set; wherein when the front end of said feeding loop claw is tilted out, said loading plug is pushed forward in the direction of the front end of the tube set; wherein when the front end of said feeding loop claw is pressed down the front end is kept away from said loading plug, so that said loading spring pushes said loading plug back to its original position; a recoil push rod movably set in said tube set, so that after said loading plug returns to its original position, the front end of said feeding loop claw is still pressed down to push said recoil push rod forward in the direction of the front end of the tube set to drive said jaw clamp said clip; and a recoil spring used to push said recoil push rod to move backward in a direction of the rear end of the the tube set. a feeding loop claw pivoted to said bolt, said feeding loop claw comprising a front end and a rear end so configured that when said feeding loop claw moves forward in the direction of the rear end of the tube set, said feeding loop claw is touched by said bump of said body so that the front end of said feeding loop claw changes from a tilted out position to a pressed down position; a loading spring to push said loading plug to move backward in the direction of the rear end of the tube set; wherein when the front end of said feeding loop claw is tilted out, said loading plug is pushed forward in the direction of the front end of the tube set; wherein when the front end of said feeding loop claw is pressed down the front end is kept away from said loading plug, so that said loading spring pushes said loading plug back to its original position; a recoil push rod movably set in said tube set, so that after said loading plug returns to its original position, the front end of said feeding loop claw is still pressed down to push said recoil push rod forward in the direction of the front end of the tube set to drive said jaw clamp said clip; and a recoil spring used to push said recoil push rod to move backward in a direction of the rear end of the the tube set.