A compound according to Formula: or a pharmaceutically acceptable salt thereof, wherein: R 1 is -C NR 7 R 8, -CN, phenyl, a 5-6 membered heteroaryl, -C NR'NR'C R 9, -C NR'OR 10, or a C 1 -C 6 alkyl group, wherein the alkyl group is substituted with one to three groups selected from halo, C 1 -C 3 alkoxy, -OH, -CN, -NR 7 R 8, -NR 7 COR 9, a 5-6 membered heteroaryl and a 5-7 membered heterocyclyl, and wherein the phenyl and heteroaryl represented by R 1 are optionally and independently substituted with 1-3 groups selected from halo, -OH, C 1 -C 3 alkoxy, -CN, -NR 7 R 8, and -CONR 7 R 8; R 2 and R 3 are independently selected from hydrogen, halo, C 1 -C 3 alkyl, and C 3 -C 6 cycloalkyl; R 4 and R 5 are independently selected from hydrogen, halo, -CN, -CO 2 R 9, C 1 -C 3 alkyl, and C 1 -C 3 haloalkyl; R 6 is hydrogen, C 1 -C 12 alkyl, C 1 -C 4 alkyl-C 1 -C 3 alkoxy-(NR'C 1 -C 6 alkyl)-C 1 -C 3 alkoxy, C 1 -C 4 alkyl-C 1 -C 3 alkoxy-C 1 -C 3 alkoxy, C 2 -C 12 alkenyl, C 3 -C 10 cycloalkyl, a 5-6 membered heteroaryl and a 5-7 membered heterocyclyl, wherein the alkyl, alkenyl, cycloalkyl, heteroaryl and heterocyclyl are optionally and independently substituted with 1-6 groups selected from a carboxyl, halo, C 1 -C 6 alkoxy, C 1 -C 6 alkyl and phenyl; each R 7 and R 8 are independently hydrogen, C 1 -C 3 alkyl, C 1 -C 3 alkoxy, phenyl, C 3 -C 6 cycloalkyl, 4-7 membered heterocyclyl, or 5-6 membered heteroaryl, wherein the alkyl, alkoxy, phenyl, cycloalkyl, heterocyclyl or heteroaryl represented by R 7 or R 8 is optionally and independently substituted with 1-6 groups selected from a 5-6 membered heterocyclyl optionally substituted with one or two -F atoms, carboxyl or -CO(OC 1-6 alkyl), 5-6 membered heteroaryl, -CN, -OH, C 1 -C 3 alkyl optionally substituted with -NH 2 or-OH, C 1 -C 3 haloalkyl, C 1 -C 3 haloalkoxy, C 1 -C 3 alkoxy -NHCO(C 1 -C 3 alkyl), -NHCO(C 1 -C 3 alkoxy), -S 2 NR'R", -NHS 2 NR'R", -NHS 2 (C 1 -C 3 alkyl), -NR'R", and -C NR'R"; each R 9 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 haloalkoxy or C 1 -C 6 alkoxy; each R 10 is a C 1 -C 3 alkyl optionally substituted with 1-6 groups selected from a 5-6 membered heterocyclyl optionally substituted with one or two -F atoms, carboxyl or -CO(OC 1-6 alkyl), a C 3 -C 6 cycloalkyl, a 5-6 membered heteroaryl, -CN, -OH, -NHCO(C 1 -C 3 alkyl), -NHCO(C 1 -C 3 alkoxy), -S 2 NR'R", -NHS 2 NR'R", -NHS 2 (C 1 -C 3 alkyl), -NR'R", or -C NR'R"; and each R' and R" is independently hydrogen, methyl, ethyl or propyl; or R' and R" are taken together with the nitrogen to which they are attached to form a 5-6 membered heterocyclyl; provided that at least one of R 2 and R 3 is other than hydrogen. R 1 is -C NR 7 R 8, -CN, phenyl, a 5-6 membered heteroaryl, -C NR'NR'C R 9, -C NR'OR 10, or a C 1 -C 6 alkyl group, wherein the alkyl group is substituted with one to three groups selected from halo, C 1 -C 3 alkoxy, -OH, -CN, -NR 7 R 8, -NR 7 COR 9, a 5-6 membered heteroaryl and a 5-7 membered heterocyclyl, and wherein the phenyl and heteroaryl represented by R 1 are optionally and independently substituted with 1-3 groups selected from halo, -OH, C 1 -C 3 alkoxy, -CN, -NR 7 R 8, and -CONR 7 R 8; R 2 and R 3 are independently selected from hydrogen, halo, C 1 -C 3 alkyl, and C 3 -C 6 cycloalkyl; R 4 and R 5 are independently selected from hydrogen, halo, -CN, -CO 2 R 9, C 1 -C 3 alkyl, and C 1 -C 3 haloalkyl; R 6 is hydrogen, C 1 -C 12 alkyl, C 1 -C 4 alkyl-C 1 -C 3 alkoxy-(NR'C 1 -C 6 alkyl)-C 1 -C 3 alkoxy, C 1 -C 4 alkyl-C 1 -C 3 alkoxy-C 1 -C 3 alkoxy, C 2 -C 12 alkenyl, C 3 -C 10 cycloalkyl, a 5-6 membered heteroaryl and a 5-7 membered heterocyclyl, wherein the alkyl, alkenyl, cycloalkyl, heteroaryl and heterocyclyl are optionally and independently substituted with 1-6 groups selected from a carboxyl, halo, C 1 -C 6 alkoxy, C 1 -C 6 alkyl and phenyl; each R 7 and R 8 are independently hydrogen, C 1 -C 3 alkyl, C 1 -C 3 alkoxy, phenyl, C 3 -C 6 cycloalkyl, 4-7 membered heterocyclyl, or 5-6 membered heteroaryl, wherein the alkyl, alkoxy, phenyl, cycloalkyl, heterocyclyl or heteroaryl represented by R 7 or R 8 is optionally and independently substituted with 1-6 groups selected from a 5-6 membered heterocyclyl optionally substituted with one or two -F atoms, carboxyl or -CO(OC 1-6 alkyl), 5-6 membered heteroaryl, -CN, -OH, C 1 -C 3 alkyl optionally substituted with -NH 2 or-OH, C 1 -C 3 haloalkyl, C 1 -C 3 haloalkoxy, C 1 -C 3 alkoxy -NHCO(C 1 -C 3 alkyl), -NHCO(C 1 -C 3 alkoxy), -S 2 NR'R", -NHS 2 NR'R", -NHS 2 (C 1 -C 3 alkyl), -NR'R", and -C NR'R"; each R 9 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 haloalkoxy or C 1 -C 6 alkoxy; each R 10 is a C 1 -C 3 alkyl optionally substituted with 1-6 groups selected from a 5-6 membered heterocyclyl optionally substituted with one or two -F atoms, carboxyl or -CO(OC 1-6 alkyl), a C 3 -C 6 cycloalkyl, a 5-6 membered heteroaryl, -CN, -OH, -NHCO(C 1 -C 3 alkyl), -NHCO(C 1 -C 3 alkoxy), -S 2 NR'R", -NHS 2 NR'R", -NHS 2 (C 1 -C 3 alkyl), -NR'R", or -C NR'R"; and each R' and R" is independently hydrogen, methyl, ethyl or propyl; or R' and R" are taken together with the nitrogen to which they are attached to form a 5-6 membered heterocyclyl; provided that at least one of R 2 and R 3 is other than hydrogen.