A computer-implemented method that, when executed by a computer, performs a method, comprising: analyzing non-invasive electrical data for a region of interest of a patient's anatomical structure to identify a plurality of zones within the ROI that contain at least one mechanism of distinct arrhythmogenic electrical activity, wherein analyzing non-invasive electrical information further comprises determining a number of mechanisms of distinct arrhythmogenic electrical activity that occur within each respective zone of the plurality of zones during at least one time interval, wherein the number of mechanisms of distinct arrhythmogenic electrical activity within each respective zone of the plurality of zones comprises at least one of a number of rotors that occur within the at least one time interval or a number of foci that occur within the at least one time interval, and a number of fast bursting cycle length that occur within the at least one time interval; analyzing invasive electrical data for a plurality of signals of interest at different spatial sites within each of the plurality of zones to determine intracardiac signal characteristics for the plurality of sites within each respective zone of the plurality of zones; evaluating a plurality of different intracardiac signal characteristics determined for each of the plurality of sites within each zone of the plurality of zones to determine a local priority among the plurality of sites within each respective zone of the plurality of zones; and generating an output that integrates the at least one mechanism of distinct arrhythmogenic electrical activity for the plurality of zones with the intracardiac signal characteristics for the plurality of sites within each respective zone of the plurality of zones. analyzing non-invasive electrical data for a region of interest of a patient's anatomical structure to identify a plurality of zones within the ROI that contain at least one mechanism of distinct arrhythmogenic electrical activity, wherein analyzing non-invasive electrical information further comprises determining a number of mechanisms of distinct arrhythmogenic electrical activity that occur within each respective zone of the plurality of zones during at least one time interval, wherein the number of mechanisms of distinct arrhythmogenic electrical activity within each respective zone of the plurality of zones comprises at least one of a number of rotors that occur within the at least one time interval or a number of foci that occur within the at least one time interval, and a number of fast bursting cycle length that occur within the at least one time interval; analyzing invasive electrical data for a plurality of signals of interest at different spatial sites within each of the plurality of zones to determine intracardiac signal characteristics for the plurality of sites within each respective zone of the plurality of zones; evaluating a plurality of different intracardiac signal characteristics determined for each of the plurality of sites within each zone of the plurality of zones to determine a local priority among the plurality of sites within each respective zone of the plurality of zones; and generating an output that integrates the at least one mechanism of distinct arrhythmogenic electrical activity for the plurality of zones with the intracardiac signal characteristics for the plurality of sites within each respective zone of the plurality of zones.