A compound, being a compound represented by Formula; or being a stereoisomer, geometric isomer, tautomer, nitrogen oxide, hydrate, solvate, or pharmaceutically acceptable salt of the compound represented by Formula: wherein X 1 and X 2 are independently C(R 7a) 2; wherein R 1 is H, D, F, Cl, Br, I, -CN, -NO 2, -OH, -NH 2, -COOH, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-8 cycloalkyl, C 1-6 halogenated alkyl, C 1-6 hydroxyl-substituted alkyl, C 1-6 alkoxyl, C 1-6 halogenated alkoxyl, -C(=O)R 7b, -C(=O)OR 7b, -OC(=O)R 7b, -C(=O)NR 8a R 8b, - NR 8 C(=O)R 7b, R 8a R 8b N-S(=O) 2 -, -R 8 N-S(=O) 2 R 7b, R 7b S(=O) 2 -, C 6-10 aryl, or heteroaryl consisting of 5-12 atoms, wherein one, two, three, four or five carbon atoms of the C 6-10 aryl or heteroaryl consisting of 5-12 atoms are independently and optionally substituted with R 10, wherein R 10 is each independently H, D, F, Cl, Br, I, -CN, -NO 2, -OH, -NH 2, -COOH, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-8 cycloalkyl, C 1-6 halogenated alkyl, C 1-6 hydroxyl-substituted alkyl, C 1-6 alkoxyl, C 1-6 halogenated alkoxyl, -C(=O)R 7b, -C(=O)OR 7b, -OC(=O)R 7b, -C(=O)NR 8a R 8b, -NR 8 C(=O)R 7b, R 8a R 8b N-S(=O) 2 -, -R 8 N-S(=O) 2 R 7b, or R 7b S(=O) 2 -; wherein R 2 is -C(=O)R 7c, -C(=O)(C(R 7a) 2) n1 R 7c, -C(=O)OR 7c, -OC(=O)R 7c, - C(=O)NR 8a R 8b, -C(=S)NR 8a R 8b, -NR 8 C(=O)R 7c, R 8a R 8b N-S(=O) 2 -, -R 8 N-S(=O) 2 R 7c, or R 7c S(=O) 2 -; wherein R 3 is H, D, F, Cl, Br, I, -CN, -NO 2, -OH, -NH 2, -COOH, oxo, or C 1-6 alkyl; wherein R 4, R 5, and R 6 are each independently H, D, F, Cl, Br, I, -CN, -NO 2, -OH, -NH 2, -COOH, or C 1-6 alkyl; wherein R 7a, R 7b, R 7c, R 8, R 8a, and R 8b are each independently H, D, F, Cl, Br, I, -CN, - NO 2, -OH, -NH 2, -COOH, C 1-6 alkyl, or C 1-6 halogenated alkyl; and wherein m1, m2, and n1 are independently 0, 1, 2, 3, or 4. wherein X 1 and X 2 are independently C(R 7a) 2; wherein R 1 is H, D, F, Cl, Br, I, -CN, -NO 2, -OH, -NH 2, -COOH, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-8 cycloalkyl, C 1-6 halogenated alkyl, C 1-6 hydroxyl-substituted alkyl, C 1-6 alkoxyl, C 1-6 halogenated alkoxyl, -C(=O)R 7b, -C(=O)OR 7b, -OC(=O)R 7b, -C(=O)NR 8a R 8b, - NR 8 C(=O)R 7b, R 8a R 8b N-S(=O) 2 -, -R 8 N-S(=O) 2 R 7b, R 7b S(=O) 2 -, C 6-10 aryl, or heteroaryl consisting of 5-12 atoms, wherein one, two, three, four or five carbon atoms of the C 6-10 aryl or heteroaryl consisting of 5-12 atoms are independently and optionally substituted with R 10, wherein R 10 is each independently H, D, F, Cl, Br, I, -CN, -NO 2, -OH, -NH 2, -COOH, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-8 cycloalkyl, C 1-6 halogenated alkyl, C 1-6 hydroxyl-substituted alkyl, C 1-6 alkoxyl, C 1-6 halogenated alkoxyl, -C(=O)R 7b, -C(=O)OR 7b, -OC(=O)R 7b, -C(=O)NR 8a R 8b, -NR 8 C(=O)R 7b, R 8a R 8b N-S(=O) 2 -, -R 8 N-S(=O) 2 R 7b, or R 7b S(=O) 2 -; wherein R 2 is -C(=O)R 7c, -C(=O)(C(R 7a) 2) n1 R 7c, -C(=O)OR 7c, -OC(=O)R 7c, - C(=O)NR 8a R 8b, -C(=S)NR 8a R 8b, -NR 8 C(=O)R 7c, R 8a R 8b N-S(=O) 2 -, -R 8 N-S(=O) 2 R 7c, or R 7c S(=O) 2 -; wherein R 3 is H, D, F, Cl, Br, I, -CN, -NO 2, -OH, -NH 2, -COOH, oxo, or C 1-6 alkyl; wherein R 4, R 5, and R 6 are each independently H, D, F, Cl, Br, I, -CN, -NO 2, -OH, -NH 2, -COOH, or C 1-6 alkyl; wherein R 7a, R 7b, R 7c, R 8, R 8a, and R 8b are each independently H, D, F, Cl, Br, I, -CN, - NO 2, -OH, -NH 2, -COOH, C 1-6 alkyl, or C 1-6 halogenated alkyl; and wherein m1, m2, and n1 are independently 0, 1, 2, 3, or 4.