Multiple hold down and separation device for spacecraft, that comprises: - a central structure comprising: - a central section with an inner hole with a cylindrical surface comprising an end stop, an inner axial shaft being provided into the inner hole, the central section also comprising a release bolt aligned with the inner axial shaft, and - at least two arms protruding from the central section and corresponding pusher means, said at least two arms axially preloaded by the pusher means at the end opposite the central section, - a support connected to the central section of the central structure and comprising attaching means, - an actuator connected to the release bolt of the central section of the central structure, wherein - the central section of the central structure additionally comprises a main bushing at least partly arranged inside the inner hole and axially guided by means of a guiding system comprising a guiding bushing on the main bushing and a guiding bushing on the surface of the inner hole, the main bushing comprising a protrusion on its outer surface, a retainer spring being provided inside the main bushing, wherein the multiple hold down and separation device for spacecraft additionally comprises: - at least two connecting levers, each one of the connecting levers connected to the end of the corresponding arm of the central structure by means of the pusher means, and - at least two hold-down assemblies placed on the periphery of the device, each one of them comprising a hold-down support and a hold-down both of them with conical mating surfaces, each hold-down support comprising a torsion spring around a torsion spring axis, each corresponding lever being articulated with the corresponding hold-down support through the corresponding torsion spring axis. - a central structure comprising: - a central section with an inner hole with a cylindrical surface comprising an end stop, an inner axial shaft being provided into the inner hole, the central section also comprising a release bolt aligned with the inner axial shaft, and - at least two arms protruding from the central section and corresponding pusher means, said at least two arms axially preloaded by the pusher means at the end opposite the central section, - a central section with an inner hole with a cylindrical surface comprising an end stop, an inner axial shaft being provided into the inner hole, the central section also comprising a release bolt aligned with the inner axial shaft, and - at least two arms protruding from the central section and corresponding pusher means, said at least two arms axially preloaded by the pusher means at the end opposite the central section, - a support connected to the central section of the central structure and comprising attaching means, - an actuator connected to the release bolt of the central section of the central structure, wherein - the central section of the central structure additionally comprises a main bushing at least partly arranged inside the inner hole and axially guided by means of a guiding system comprising a guiding bushing on the main bushing and a guiding bushing on the surface of the inner hole, the main bushing comprising a protrusion on its outer surface, a retainer spring being provided inside the main bushing, - at least two connecting levers, each one of the connecting levers connected to the end of the corresponding arm of the central structure by means of the pusher means, and - at least two hold-down assemblies placed on the periphery of the device, each one of them comprising a hold-down support and a hold-down both of them with conical mating surfaces, each hold-down support comprising a torsion spring around a torsion spring axis, each corresponding lever being articulated with the corresponding hold-down support through the corresponding torsion spring axis.