Loading machine for cartridges with a metal case comprising: - a frame structure; - feed means for a plurality of cases having a given caliber (c) and a longitudinally extending axis (x); - feed means for a plurality of ogival balls adapted to act as bullets; - feed means for gunpowder; - a first operating beam having an alternating vertical translation movement, provided with working tools having a vertical axis (y), adapted to load said cases; - feed and conveying means of said cases during loading; - means for ejecting the loaded cartridges; - motor means for activation of kinematic mechanisms; - a control unit; wherein said feed means of said cases comprise: - a race adapted to support and to allow feed of said cases in a given direction; - a conveyor guide, arranged parallel to said race and comb shaped to define a plurality of seats, adapted to contain said cases and to convey them along said race, to position them, according to the various filling steps, under respective working tools, characterized in that: - said conveyor guide comprises a plurality of bushings, each bushing comprising at least a first conical surface and a hole adapted to house one of said cases and being housed in one of said seats, wherein the outer diameter of said bushing is less than the inner dimension (d) of said seats so as to have a minimum freedom of movement between bushing and respective seat; - said machine comprises a second operating beam, having an alternating vertical translation movement coordinated with the alternating vertical translation movement of said first operating beam, wherein said second operating beam is provided with a plurality of hollow centering cylinders, having a vertical axis (z) and a second conical surface inside them, each centering cylinder being arranged so that its vertical axis (z) coincides with the vertical axis (y) of one of said tools, wherein coupling between the first conical surface of each bushing and the second conical surface of a corresponding centering cylinder causes shifting of said bushing in said seat, and consequently shifting of the case housed in said bushing, to obtain coaxiality between the longitudinal axis (x) of said case and the vertical axis (z) of said centering cylinder. - a frame structure; - feed means for a plurality of cases having a given caliber (c) and a longitudinally extending axis (x); - feed means for a plurality of ogival balls adapted to act as bullets; - feed means for gunpowder; - a first operating beam having an alternating vertical translation movement, provided with working tools having a vertical axis (y), adapted to load said cases; - feed and conveying means of said cases during loading; - means for ejecting the loaded cartridges; - motor means for activation of kinematic mechanisms; - a control unit; - a race adapted to support and to allow feed of said cases in a given direction; - a conveyor guide, arranged parallel to said race and comb shaped to define a plurality of seats, adapted to contain said cases and to convey them along said race, to position them, according to the various filling steps, under respective working tools, - said conveyor guide comprises a plurality of bushings, each bushing comprising at least a first conical surface and a hole adapted to house one of said cases and being housed in one of said seats, wherein the outer diameter of said bushing is less than the inner dimension (d) of said seats so as to have a minimum freedom of movement between bushing and respective seat; - said machine comprises a second operating beam, having an alternating vertical translation movement coordinated with the alternating vertical translation movement of said first operating beam, wherein said second operating beam is provided with a plurality of hollow centering cylinders, having a vertical axis (z) and a second conical surface inside them, each centering cylinder being arranged so that its vertical axis (z) coincides with the vertical axis (y) of one of said tools,