A compound selected from the group consisting of: 4-Amino-6-{3,4- cis -4-[1-(2-azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-pyrimidine-5-carbonitrile (racemic) ("1"); 4-Amino-6-{3,4- cis -4-[1-(2-azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-pyrimidine-5-carboxamide (racemic) ("2"); 4-amino-6-[(3R,4S)-4-[1-[2-(azetidin-1-yl)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]-3-fluoro-1-piperidyl]pyrimidine-5-carboxamide (chiral) ("3"); 4-amino-6-[(3S,4R)-4-[1-[2-(azetidin-1-yl)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]-3-fluoro-1-piperidyl]pyrimidine-5-carboxamide (chiral) ("4"); 4-Amino-6-{3,4- cis -4-[1-(2-azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-methyl-piperidin-1-yl}-pyrimidine-5-carbonitrile (racemic) ("5"); 4-Amino-6-{3,4- cis -4-[1-(2-azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-methyl-piperidin-1-yl}-pyrimidine-5-carboxamide (racemic) ("6"); 4-amino-6-{3,4- trans -4-[1-(2-azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-pyrimidine-5-carbonitrile (racemic) ("7"); 4-Amino-6-{3,4- trans -4-[1-(2-azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-pyrimidine-5-carboxamide (racemic) ("8"); 4-amino-6-{3,4- cis -4-[1-(2-dimethylaminoethyl)-4-(4-fluoro-3-methyl-phenyl)imidazol-2-yl]-3-fluoro-1-piperidyl]}-pyrimidine-5-carbonitrile (racemic) ("9"); 6-{3,4- cis -4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-5-chloro-pyrimidin-4-ylamine (racemic) ("10"); 6-{3,4- trans -4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-5-chloro-pyrimidin-4-ylamine (racemic) ("11"); 5-chloro-6-{3,4- cis --4-[1-(2-dimethylamino-ethyl)-4-(4-fluoro-3-methyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-pyrimidin-4-ylamine (racemic) ("12"); 6-{3,4- cis -4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-5-ethyl-pyrimidin-4-ylamine (racemic) ("13"); 4-Amino-6-{3,4- cis -4-[1-(2-dimethylamino-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-pyrimidine-5-carbonitrile (racemic) ("14"); 4-Amino-6-{3,4- cis -4-[1-(2-dimethylamino-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-pyrimidine-5-carbonitrile (racemic) ("15"); 6-{3,4- cis -4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-5-ethoxy-pyrimidin-4-ylamine (racemic) ("16"). or pharmaceutically acceptable salts, solvates, or solvates of salts thereof. 4-Amino-6-{3,4- cis -4-[1-(2-azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-pyrimidine-5-carbonitrile (racemic) ("1"); 4-Amino-6-{3,4- cis -4-[1-(2-azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-pyrimidine-5-carboxamide (racemic) ("2"); 4-amino-6-[(3R,4S)-4-[1-[2-(azetidin-1-yl)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]-3-fluoro-1-piperidyl]pyrimidine-5-carboxamide (chiral) ("3"); 4-amino-6-[(3S,4R)-4-[1-[2-(azetidin-1-yl)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]-3-fluoro-1-piperidyl]pyrimidine-5-carboxamide (chiral) ("4"); 4-Amino-6-{3,4- cis -4-[1-(2-azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-methyl-piperidin-1-yl}-pyrimidine-5-carbonitrile (racemic) ("5"); 4-Amino-6-{3,4- cis -4-[1-(2-azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-methyl-piperidin-1-yl}-pyrimidine-5-carboxamide (racemic) ("6"); 4-amino-6-{3,4- trans -4-[1-(2-azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-pyrimidine-5-carbonitrile (racemic) ("7"); 4-Amino-6-{3,4- trans -4-[1-(2-azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-pyrimidine-5-carboxamide (racemic) ("8"); 4-amino-6-{3,4- cis -4-[1-(2-dimethylaminoethyl)-4-(4-fluoro-3-methyl-phenyl)imidazol-2-yl]-3-fluoro-1-piperidyl]}-pyrimidine-5-carbonitrile (racemic) ("9"); 6-{3,4- cis -4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-5-chloro-pyrimidin-4-ylamine (racemic) ("10"); 6-{3,4- trans -4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-5-chloro-pyrimidin-4-ylamine (racemic) ("11"); 5-chloro-6-{3,4- cis --4-[1-(2-dimethylamino-ethyl)-4-(4-fluoro-3-methyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-pyrimidin-4-ylamine (racemic) ("12"); 6-{3,4- cis -4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-5-ethyl-pyrimidin-4-ylamine (racemic) ("13"); 4-Amino-6-{3,4- cis -4-[1-(2-dimethylamino-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-pyrimidine-5-carbonitrile (racemic) ("14"); 4-Amino-6-{3,4- cis -4-[1-(2-dimethylamino-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-pyrimidine-5-carbonitrile (racemic) ("15"); 6-{3,4- cis -4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-3-fluoro-piperidin-1-yl}-5-ethoxy-pyrimidin-4-ylamine (racemic) ("16").