mhurhangee/ep-ind-claims huggingface dataset:
A method for identifying a cancer as likely to respond to an anti-Folate receptor 1 (FOLR1) immunoconjugate, the method comprising: (a) contacting a biological sample comprising cells from the cancer with a detection antibody or antigen binding fragment thereof that specifically binds FOLR1; (b) detecting binding of the detection antibody or antigen binding fragment thereof to the biological sample of step (a) using a detection method; (c) assigning a score to the binding of step (b), wherein the score is assigned based on comparison to one or more reference samples; and (d) comparing the score in step (c) to the score of one or more reference samples, wherein a score for the cancer FOLR1 level that is greater than the score for a normal or low FOLR1 expressing reference sample or a score for the cancer FOLR1 level that is equal to or greater than the score for a high FOLR1 expressing reference sample identifies the cancer as likely to respond to the anti-FOLR1 immunoconjugate, wherein the anti-FOLR1 immunoconjugate comprises an anti-FOLR1 antibody, a linker, and a cytotoxic agent, wherein the anti-FOLR1 antibody of the anti-FOLR1 immunoconjugate comprises: (i) a heavy chain variable domain comprising the amino acid sequence of SEQ ID NO: 3 (huMovl9 vHC) and a light chain variable domain comprising the amino acid sequence of SEQ ID NO: 4 (huMov19 vLCv1.00) or (ii) a heavy chain variable domain comprising the amino acid sequence of SEQ ID NO: 3 (huMov19 vHC) and a light chain variable domain comprising the amino acid sequence of SEQ ID NO: 5 (huMov19 vLCv1.60). (a) contacting a biological sample comprising cells from the cancer with a detection antibody or antigen binding fragment thereof that specifically binds FOLR1; (b) detecting binding of the detection antibody or antigen binding fragment thereof to the biological sample of step (a) using a detection method; (c) assigning a score to the binding of step (b), wherein the score is assigned based on comparison to one or more reference samples; and (d) comparing the score in step (c) to the score of one or more reference samples, wherein a score for the cancer FOLR1 level that is greater than the score for a normal or low FOLR1 expressing reference sample or a score for the cancer FOLR1 level that is equal to or greater than the score for a high FOLR1 expressing reference sample identifies the cancer as likely to respond to the anti-FOLR1 immunoconjugate, (i) a heavy chain variable domain comprising the amino acid sequence of SEQ ID NO: 3 (huMovl9 vHC) and a light chain variable domain comprising the amino acid sequence of SEQ ID NO: 4 (huMov19 vLCv1.00) or (ii) a heavy chain variable domain comprising the amino acid sequence of SEQ ID NO: 3 (huMov19 vHC) and a light chain variable domain comprising the amino acid sequence of SEQ ID NO: 5 (huMov19 vLCv1.60).
A system comprising: a plurality of solar modules including mounting slots formed in a sidewall of the solar module; a torque tube configured to support the solar modules such that the solar modules can be rotated; a plurality of mounting brackets (100, 200, 300) configured for integration with the torque tube and to which the plurality of solar modules are mounted; and at least one first retainer assembly connected to one of the plurality of mounting brackets (100, 200, 300), the first retainer assembly including a through bolt, a spring, a slotted washer, a mounting tab, and nut, wherein the through bolt is inserted through a hole of a rail of the one of the plurality of mounting brackets (100, 200, 300) such that a head of through bolt abuts a bottom surface of the rail, wherein the spring, the slotted washer, and the mounting tab are received over a protruding portion of the through bolt proximate a top surface of the rail, wherein the nut is tightened to the through bolt and a force of the spring causes the head of the through bolt to rest against the bottom surface of the rail, wherein the slotted washer is slotted to assist in locking the spring so that it does not fall through the hole of the rail, and wherein when a solar module is placed on the mounting bracket (100, 200, 300) and supported by the torque tube the mounting tab is received in the mounting slot of the solar module. a plurality of solar modules including mounting slots formed in a sidewall of the solar module; a torque tube configured to support the solar modules such that the solar modules can be rotated; a plurality of mounting brackets (100, 200, 300) configured for integration with the torque tube and to which the plurality of solar modules are mounted; and at least one first retainer assembly connected to one of the plurality of mounting brackets (100, 200, 300), the first retainer assembly including a through bolt, a spring, a slotted washer, a mounting tab, and nut, wherein the through bolt is inserted through a hole of a rail of the one of the plurality of mounting brackets (100, 200, 300) such that a head of through bolt abuts a bottom surface of the rail, wherein the spring, the slotted washer, and the mounting tab are received over a protruding portion of the through bolt proximate a top surface of the rail, wherein the nut is tightened to the through bolt and a force of the spring causes the head of the through bolt to rest against the bottom surface of the rail, wherein the slotted washer is slotted to assist in locking the spring so that it does not fall through the hole of the rail, and wherein when a solar module is placed on the mounting bracket (100, 200, 300) and supported by the torque tube the mounting tab is received in the mounting slot of the solar module.
A microneedle array comprising microneedles containing noncrystalline polylactic acid, wherein the crystallinity of the polylactic acid is 38% or less and the microneedles are transparent or translucent.
A plastic cap including a cap body fixed to a mouth portion of a container and an upper lid mounted on said cap body so as to be opened and closed, said cap body having a top panel and a skirt falling down from a circumferential edge of the top panel, said top panel having an opening or a predetermined opening area for pouring the liquid in the container, and on an outer side of said opening or the predetermined opening area in the upper surface of said top panel, a pouring protrusion (11; 110) and an annular small protrusion for engagement with the upper lid being formed, said pouring protrusion (11; 110) serving as a guide for pouring the liquid in the container, and said annular small protrusion being positioned on an outer side of said pouring protrusion (11; 110) wherein: a bill is formed at an upper end portion of said pouring protrusion (11; 110), the bill protruding outward in an inclined manner and assuming a triangular shape as viewed from the upper surface thereof; a lower end portion of an inner surface of said pouring protrusion (11; 110) is a seal surface that extends in a vertical direction; a groove is formed in the inner surface of said pouring protrusion (11; 110) extending from an upper end portion of said bill up to an upper end portion of said seal surface; and a seal ring is formed on an inner surface of said upper lid so as to come into close contact with said seal surface when said upper lid is closed, characterized in that a buffer protrusion is formed protruding outward on the outer surface of said pouring protrusion (11; 110), and the buffer protrusion is positioned on a lower portion than said bill and on a higher portion than said annular small protrusion for engagement with the upper lid. a bill is formed at an upper end portion of said pouring protrusion (11; 110), the bill protruding outward in an inclined manner and assuming a triangular shape as viewed from the upper surface thereof; a lower end portion of an inner surface of said pouring protrusion (11; 110) is a seal surface that extends in a vertical direction; a groove is formed in the inner surface of said pouring protrusion (11; 110) extending from an upper end portion of said bill up to an upper end portion of said seal surface; and a seal ring is formed on an inner surface of said upper lid so as to come into close contact with said seal surface when said upper lid is closed, characterized in that a buffer protrusion is formed protruding outward on the outer surface of said pouring protrusion (11; 110), and the buffer protrusion is positioned on a lower portion than said bill and on a higher portion than said annular small protrusion for engagement with the upper lid.
An anti-ice system for a gas turbine engine, comprising: a first thermally conductive applique comprising a first heating circuit bonded to one or more airfoil surfaces, wherein the first thermally conductive applique comprises a metallic layer covering the first heating circuit; and a first conductive layer electrically coupling the first heating circuit and a power generating device, the power generating device comprising: a first component configured to generate a current; a first magnet and a second magnet, wherein the first and second magnets are non-rotating structures; characterised by the first magnet being located over a first surface of the first component; the second magnet being located over a second surface of the first component opposite the first surface of the first component; the first component being a Faraday disk mounted to a rotor and configured to rotate in a plane perpendicular to a static magnetic field created by the first and second magnets, and wherein a first end of the first conductive layer is electrically coupled to a radially outward end of the first component, and wherein a second end of the first conductive layer is electrically coupled to a radially inward end of the first component. a first thermally conductive applique comprising a first heating circuit bonded to one or more airfoil surfaces, wherein the first thermally conductive applique comprises a metallic layer covering the first heating circuit; and a first conductive layer electrically coupling the first heating circuit and a power generating device, the power generating device comprising: a first component configured to generate a current; a first magnet and a second magnet, wherein the first and second magnets are non-rotating structures; a first component configured to generate a current; a first magnet and a second magnet, wherein the first and second magnets are non-rotating structures; characterised by the first magnet being located over a first surface of the first component; the second magnet being located over a second surface of the first component opposite the first surface of the first component; the first component being a Faraday disk mounted to a rotor and configured to rotate in a plane perpendicular to a static magnetic field created by the first and second magnets, and wherein a first end of the first conductive layer is electrically coupled to a radially outward end of the first component, and wherein a second end of the first conductive layer is electrically coupled to a radially inward end of the first component.
A method of identifying the relative proportions by percent of a plurality of end member components in a sample of reservoir rock taken from a specific oil field by analysis of pyrolytic characterizing data (pcd), the method comprising the steps of: a. identifying the end-member components known to be present in reservoir rock in the oil field; b. preparing individual pyrograms consisting of pcd for each of the components identified in step (a); c. storing the pcd for each component in a digital data file; d. conducting a pyrolytic analysis of a sample from the oil field of reservoir rock that contains one or more hydrocarbon and organic matter components of the type identified in step (a) to obtain pcd for the sample; e. comparing the pcd for the sample with the pcd obtained in step (b) for each of the components, measuring and recording the difference between the sample pcd and the pcd for each of the components; f. applying a statistical analysis to minimize the aggregate differences between the pcd for the sample and a combination of pcd selected from the components; g. recording for retention and display for analysis the resulting pcd that constitutes the minimum aggregate error over the temperature range of the pyrolytic analysis; and h. analyzing the displayed data to identify the respective components. a. identifying the end-member components known to be present in reservoir rock in the oil field; b. preparing individual pyrograms consisting of pcd for each of the components identified in step (a); c. storing the pcd for each component in a digital data file; d. conducting a pyrolytic analysis of a sample from the oil field of reservoir rock that contains one or more hydrocarbon and organic matter components of the type identified in step (a) to obtain pcd for the sample; e. comparing the pcd for the sample with the pcd obtained in step (b) for each of the components, measuring and recording the difference between the sample pcd and the pcd for each of the components; f. applying a statistical analysis to minimize the aggregate differences between the pcd for the sample and a combination of pcd selected from the components; g. recording for retention and display for analysis the resulting pcd that constitutes the minimum aggregate error over the temperature range of the pyrolytic analysis; and h. analyzing the displayed data to identify the respective components.
A method of preparing dry core-shell microcapsules from an aqueous dispersion of such capsules, comprising spraying the dispersion through a two-fluid air-liquid nozzle into a heated chamber having an upper part and a lower part, the spraying taking place in the upper part and the lower part being provided with a means of continuous capsule removal, selected from rotary valves, double-flap valves and cycle valves.
A computer program product having a plurality of instructions for causing a processor of a computer to initialize a virtual machine (VM, 150) that subsequently executes an application to render an object (310, 311, 320, 321) on a display of the computer the computer program product causing to initialize by the following steps: providing a localization class that has at least one class variable without initialization, wherein the class variable represents an object (310, 311, 320, 321) of the display, the class variable being part of the application; providing a markup language document comprising object representations (310', 311', 320', 321') of the object (310, 311, 320, 321) for at least two distinct natural languages; selecting a property value identifying one of the at least two distinct natural languages, wherein the property value is assigned to an auxiliary variable; loading the localization class if the localization class is used the first time; if the loading was successful, loading the markup language document and initializing the the class variable of the localization class by the following steps: if the loading of the markup language document was successful, reading at least one of the object representations (310', 311', 320', 321') from the markup language document in dependence on the selected property value assigned to the auxiliary variable; and assigning the at least one of the object representations (310', 311', 320', 321') to the class variable in the localization class. providing a localization class that has at least one class variable without initialization, wherein the class variable represents an object (310, 311, 320, 321) of the display, the class variable being part of the application; providing a markup language document comprising object representations (310', 311', 320', 321') of the object (310, 311, 320, 321) for at least two distinct natural languages; selecting a property value identifying one of the at least two distinct natural languages, wherein the property value is assigned to an auxiliary variable; loading the localization class if the localization class is used the first time; if the loading was successful, loading the markup language document and initializing the the class variable of the localization class by the following steps: if the loading of the markup language document was successful, reading at least one of the object representations (310', 311', 320', 321') from the markup language document in dependence on the selected property value assigned to the auxiliary variable; and assigning the at least one of the object representations (310', 311', 320', 321') to the class variable in the localization class. if the loading of the markup language document was successful, reading at least one of the object representations (310', 311', 320', 321') from the markup language document in dependence on the selected property value assigned to the auxiliary variable; and assigning the at least one of the object representations (310', 311', 320', 321') to the class variable in the localization class.
A coin separation device, comprising - a conveying device for conveying coins from an inlet container in a conveying direction along a conveying line, and - a checking device arranged on the conveying line for recognizing a coin conveyed along the conveying line, characterized by an acceleration device which is formed to accelerate a coin conveyed along the conveying line and recognized by the checking device in conveying direction such that the coin is conveyed from the conveying line into a coin collection device, wherein the acceleration device includes a step motor and an acceleration element driven by the step motor for accelerating a coin, wherein the acceleration element is formed by a paddle wheel rotatable about an axis of rotation with paddles for acting on a coin. - a conveying device for conveying coins from an inlet container in a conveying direction along a conveying line, and - a checking device arranged on the conveying line for recognizing a coin conveyed along the conveying line,
A system for dispensing a pressurized product comprising a pump comprising a body, a rod, and a pushbutton mounted on the rod for reversibly actuating said rod in said body, the body being equipped with means allowing an internal chamber of said body to be supplied with product from a source, said rod being equipped with a valve which is arranged in the internal chamber, having a stable state of closure of a dispensing path formed through the rod and the pushbutton to a dispensing orifice, and a state constrained by actuation of the rod wherein said dispensing path is in communication with the internal chamber, said dispensing system being characterized in that it comprises at least one part made of a material M comprising an aliphatic polyketone.
Method for controlling the lateral position of a vehicle on a traffic lane, characterized in that it comprises: - a step for calculating a reference state vector (Xref) of the vehicle, - a step for calculating an observed state vector (Xobs) of the vehicle, - a step for calculating a steering angle setpoint (δc) for the steerable wheels of the vehicle as a function of the difference (Xerr) between the reference state vector (Xref) and the observed state vector (Xobs), the control method comprising an initialization step executed at the moment the control method is activated, the initialization step comprising a substep for calculating a component of an initial observed state vector such that the steering angle setpoint (δc) for the steerable wheels at the moment the control method is activated is equal to a measured steering angle value (δm) of the steerable wheels at the moment the control method is activated. - a step for calculating a reference state vector (Xref) of the vehicle, - a step for calculating an observed state vector (Xobs) of the vehicle, - a step for calculating a steering angle setpoint (δc) for the steerable wheels of the vehicle as a function of the difference (Xerr) between the reference state vector (Xref) and the observed state vector (Xobs),
Method for dismounting a guide arrangement for a sliding door with a guide means (20, 30) which can be moved along a guide rail and is held on a sliding door, wherein the guide means (20, 30) can be moved into three different positions, namely a mounted position in which the guide means (20, 30) is engaged with the guide rail, a mounting position in which the guide means (20, 30) is disengaged from the guide rail and can therefore be dismounted, and an escape position in which the guide means (20, 30) is located entirely above a lower surface of the sliding door, comprising the following steps: - moving the guide means (20, 30) from the mounted position to the mounting position where the guide means (20, 30) is disposed out of engagement with the guide rail, and - lowering the sliding door onto a floor, whereby the guide means (20, 30) is moved from the mounting position to the escape position. - moving the guide means (20, 30) from the mounted position to the mounting position where the guide means (20, 30) is disposed out of engagement with the guide rail, and - lowering the sliding door onto a floor, whereby the guide means (20, 30) is moved from the mounting position to the escape position.
A control apparatus comprising: an angle control unit configured to change a tilt angle by tilting an imaging sensor relative to a plane orthogonal to an optical axis of an imaging optical system; a first determination unit configured to determine a first area from among a plurality of areas in an image based on distance information of each of the plurality of areas; an evaluation value acquisition unit configured to acquire a contrast evaluation value of imaging signals of each of second areas excluding the first area among the plurality of areas by changing the tilt angle through the angle control unit, wherein said contrast evaluation values of respective second areas are acquired for each tilt angle, and a maximum contrast evaluation value among the acquired contrast evaluation values is determined; and a second determination unit configured to determine for each area, as an optimal tilt angle, a tilt angle corresponding to the maximum contrast evaluation value acquired by the evaluation value acquisition unit, and determining the tilt angle of the image sensor based on the optimal tilt angle determined for each area, characterized in that the angle control unit tilts the image sensor relative to the plane orthogonal to the optical axis of the imaging optical system so as to obtain the tilt angle determined by the second determination unit. an angle control unit configured to change a tilt angle by tilting an imaging sensor relative to a plane orthogonal to an optical axis of an imaging optical system; a first determination unit configured to determine a first area from among a plurality of areas in an image based on distance information of each of the plurality of areas; an evaluation value acquisition unit configured to acquire a contrast evaluation value of imaging signals of each of second areas excluding the first area among the plurality of areas by changing the tilt angle through the angle control unit, wherein said contrast evaluation values of respective second areas are acquired for each tilt angle, and a maximum contrast evaluation value among the acquired contrast evaluation values is determined; and a second determination unit configured to determine for each area, as an optimal tilt angle, a tilt angle corresponding to the maximum contrast evaluation value acquired by the evaluation value acquisition unit, and determining the tilt angle of the image sensor based on the optimal tilt angle determined for each area, characterized in that the angle control unit tilts the image sensor relative to the plane orthogonal to the optical axis of the imaging optical system so as to obtain the tilt angle determined by the second determination unit.