mhurhangee/ep-ind-claims huggingface dataset:
An expression vector for mammalian cells comprising the following (a), (b) and (c): (a) a translation-impaired dihydrofolate reductase gene cassette (translation-impaired DHFR gene cassette) comprising a region with altered codons, wherein the altered codons comprise GCA for alanine, CGA for arginine, AAU for asparagine, GAU for aspartic acid, UGU for cysteine, CAA for glutamine, GAA for glutamic acid, GGU for glycine, CAU for histidine, UUA for leucine, AAA for lysine, CCA for proline, UUU for phenylalanine, UCA for serine, ACU for threonine, UAU for tyrosine, and/or GUA for valine, and wherein the region with altered codons accounts for 30% or more of the full length of the DHFR gene from the 5' end of the DHFR gene; (b) a gene cassette comprising a cloning site for integration of a foreign gene between a transcriptionally active promoter and a stable polyadenylation signal; and (c) ubiquitously acting chromatin opening elements (UCOEs) introduced in such positions that the gene cassette of (b) is sandwiched therebetween, wherein the UCOEs comprise the nucleotide sequence as shown in SEQ ID NO: 1. (a) a translation-impaired dihydrofolate reductase gene cassette (translation-impaired DHFR gene cassette) comprising a region with altered codons, wherein the altered codons comprise GCA for alanine, CGA for arginine, AAU for asparagine, GAU for aspartic acid, UGU for cysteine, CAA for glutamine, GAA for glutamic acid, GGU for glycine, CAU for histidine, UUA for leucine, AAA for lysine, CCA for proline, UUU for phenylalanine, UCA for serine, ACU for threonine, UAU for tyrosine, and/or GUA for valine, and wherein the region with altered codons accounts for 30% or more of the full length of the DHFR gene from the 5' end of the DHFR gene; (b) a gene cassette comprising a cloning site for integration of a foreign gene between a transcriptionally active promoter and a stable polyadenylation signal; and (c) ubiquitously acting chromatin opening elements (UCOEs) introduced in such positions that the gene cassette of (b) is sandwiched therebetween, wherein the UCOEs comprise the nucleotide sequence as shown in SEQ ID NO: 1.
A pressure control device, the pressure control device comprising a first dome pressure reducer, the first dome pressure reducer comprising a first control gas port, a first gas inlet and a first gas outlet, the first gas outlet being connected to a first pressure sensing device, characterized in that the pressure control device has a first piston accumulator, the first piston accumulator having a first gas side and a first fluid side, the first gas side of the first piston accumulator being connected in a gas-conducting manner to the first control gas opening of the first dome pressure reducer.
Radial compressor for an exhaust-gas turbocharger, in particular of an internal combustion engine, comprising: - a housing having an axial inlet duct and a radial outlet duct, which housing at least partially surrounds a compressor chamber, wherein a cutout is incorporated in the housing on the inlet duct side, - a compressor wheel arranged in the compressor chamber and intended for delivering and compressing a gas from the inlet duct to the outlet duct, - means for adapting the inner housing contour, comprising: - an axially displaceable housing insert which is arranged in the compressor chamber in a region between the housing and the compressor wheel, - a rotary disc which is mounted by means of a journal engaging in the cutout so as to be rotatable about the inlet duct and which is arranged circumferentially of the inlet duct, wherein the journal is arranged perpendicularly to an axis of rotation of the compressor wheel, and the cutout is formed obliquely, in particular so as to extend with a gradient, - a piston which is arranged between the rotary disc and the housing insert, wherein the means for adapting the inner housing contour are designed to control a gap width between the compressor wheel and the housing insert by virtue of the rotary disc transmitting a force to the housing insert via the piston. - a housing having an axial inlet duct and a radial outlet duct, which housing at least partially surrounds a compressor chamber, wherein a cutout is incorporated in the housing on the inlet duct side, - a compressor wheel arranged in the compressor chamber and intended for delivering and compressing a gas from the inlet duct to the outlet duct, - means for adapting the inner housing contour, comprising: - an axially displaceable housing insert which is arranged in the compressor chamber in a region between the housing and the compressor wheel, - a rotary disc which is mounted by means of a journal engaging in the cutout so as to be rotatable about the inlet duct and which is arranged circumferentially of the inlet duct, wherein the journal is arranged perpendicularly to an axis of rotation of the compressor wheel, and the cutout is formed obliquely, in particular so as to extend with a gradient, - a piston which is arranged between the rotary disc and the housing insert, - an axially displaceable housing insert which is arranged in the compressor chamber in a region between the housing and the compressor wheel, - a rotary disc which is mounted by means of a journal engaging in the cutout so as to be rotatable about the inlet duct and which is arranged circumferentially of the inlet duct, wherein the journal is arranged perpendicularly to an axis of rotation of the compressor wheel, and the cutout is formed obliquely, in particular so as to extend with a gradient, - a piston which is arranged between the rotary disc and the housing insert,
Medical compress comprising at least 8 layers of a textile flat web material, wherein each layer is connected to a further layer via at least one folded edge, and at least two folded edges are perpendicular to each other, and the compress is formed from a rectangular material section of the flat web material having two parallel cut edges A (14, 15) lying opposite each other and having two parallel cut edges B (16, 17) lying opposite each other, wherein the edge length a of the cut edges A is greater than the edge length b of the cut edges B, characterized in that the compress is folded in such a way that the compress comprises a first enclosing edge formed from at least one first folded edge (26a, 26b, 26c, 27a, 27b, 27c) and one second folded edge, wherein the first folded edge (26a, 26b, 26c, 27a, 27b, 27c) connects directly adjacent layers or partial sections of the directly adjacent layers and is formed parallel to the cut edges B (16, 17), and the second folded edge connects the outer layers forming the contact surfaces (61, 62) of the compress, and wherein each outer edge (64, 65, 66, 67) of the compress is formed exclusively from folded edges or enclosing edges, wherein the compress, viewed in cross section, has a first 8-layer edge region and a second 12-layer edge region, and the compress is folded in such a way that the outer layers forming the contact surfaces of the compress have the shape of a rectangle or of a square.
Mast element, in particular leader element, for a construction machine, with an elongate, hollow mast profile, which is approximately rectangular in cross section and comprises a linear guide for a mast carriage on its outer side along a longitudinal direction of the mast, characterized in that at least one diagonal reinforcement element (30, 40) extends within the mast profile along the longitudinal direction of the mast, which is arranged at an oblique angle to the sides of the approximately rectangular mast profile.
A fine fiber comprising a core phase and a coating phase; wherein the fine fiber has an average fiber diameter of no greater than 10 μm; wherein the core phase comprises a polymer and optionally a resinous aldehyde composition, and the coating phase comprises a resinous aldehyde composition; and further wherein at least a portion of the polymer is crosslinked by the resinous aldehyde composition; wherein the weight ratio of the polymer to resinous aldehyde composition ranges from 100:125 to 100:40.
A pharmaceutical composition comprising an amount of citrulline effective for use in treating subjects at risk for suffering or suffering from bronchopulmonary dysplasia.
An optical fiber assembly comprising: a launching fiber consisting of a single fiber having a receiving end and a transmitting end; an illuminating fiber having a receiving end and a transmitting end; where the receiving end of the single launching fiber is operative to receive light from a light source and the transmitting end of the single launching fiber is operative to transmit light to the receiving end of the illuminating fiber; where the single launching fiber contacts the illuminating fiber in a manner so as to be offset from a center of a cross-sectional area of the illuminating fiber; and where the single launching fiber has a diameter that is 1/8 to 1/2 of a diameter of the illuminating fiber; and a lens that is operative to contact the transmitting end of the illuminating fiber; where the optical fiber assembly transmits light received from the light source at a divergence angle of greater than 60 degrees. a launching fiber consisting of a single fiber having a receiving end and a transmitting end; an illuminating fiber having a receiving end and a transmitting end; where the receiving end of the single launching fiber is operative to receive light from a light source and the transmitting end of the single launching fiber is operative to transmit light to the receiving end of the illuminating fiber; where the single launching fiber contacts the illuminating fiber in a manner so as to be offset from a center of a cross-sectional area of the illuminating fiber; and where the single launching fiber has a diameter that is 1/8 to 1/2 of a diameter of the illuminating fiber; and a lens that is operative to contact the transmitting end of the illuminating fiber; where the optical fiber assembly transmits light received from the light source at a divergence angle of greater than 60 degrees.
An apparatus for generating a constant current pulse wave, the apparatus comprising: a charge unit receiving a current and charging electric charges; a converter unit applying a constant voltage to a flash lamp during a first reference time and applying a constant current to the flash lamp during a second reference time by using the electric charges charged in the charge unit; and a controller (3, 8) operating in a constant voltage control mode to transmit a constant voltage control signal for controlling the converter unit to output the constant voltage, to the converter unit during the first reference time and operating in a constant current control mode to transmit a constant current control signal for controlling the converter unit to output the constant current, to the converter unit during the second reference time. a charge unit receiving a current and charging electric charges; a converter unit applying a constant voltage to a flash lamp during a first reference time and applying a constant current to the flash lamp during a second reference time by using the electric charges charged in the charge unit; and a controller (3, 8) operating in a constant voltage control mode to transmit a constant voltage control signal for controlling the converter unit to output the constant voltage, to the converter unit during the first reference time and operating in a constant current control mode to transmit a constant current control signal for controlling the converter unit to output the constant current, to the converter unit during the second reference time.
Apparatus, comprising: a probe, which is positionable adjacent to an eye of a patient and configured to irradiate a trabecular meshwork of the eye with one or more optical beams that traverse a sclera of the eye, the apparatus being configured such that the probe does not make physical contact with the eye; and a processor, which is configured to select one or more target regions of the trabecular meshwork; acquire images of a sclera and a limbus of the eye using a camera; automatically identify the target regions of the trabecular meshwork based on the images of the sclera around the limbus and control the probe to irradiate with the optical beams multiple points, which lie on a region around the junction of the cornea and the sclera being a circle having a diameter between 10-14 millimeters around a cornea of the eye, so as to irradiate the automatically-identified target regions of the trabecular meshwork. a probe, which is positionable adjacent to an eye of a patient and configured to irradiate a trabecular meshwork of the eye with one or more optical beams that traverse a sclera of the eye, the apparatus being configured such that the probe does not make physical contact with the eye; and a processor, which is configured to select one or more target regions of the trabecular meshwork; acquire images of a sclera and a limbus of the eye using a camera; automatically identify the target regions of the trabecular meshwork based on the images of the sclera around the limbus and control the probe to irradiate with the optical beams multiple points, which lie on a region around the junction of the cornea and the sclera being a circle having a diameter between 10-14 millimeters around a cornea of the eye, so as to irradiate the automatically-identified target regions of the trabecular meshwork.
A slackline device comprising: - a main body having at least one bearing portion and two mutually opposite end portions (18, 20) which are disposed so as to be elevated in relation to the at least one bearing portion; and - a webbing which in an assembled state of the slackline device is tensioned between the two end portions (18, 20) of the main body, characterized in that the main body in a longitudinal section has a camber profile and is configured to be more elastic than the webbing. - a main body having at least one bearing portion and two mutually opposite end portions (18, 20) which are disposed so as to be elevated in relation to the at least one bearing portion; and - a webbing which in an assembled state of the slackline device is tensioned between the two end portions (18, 20) of the main body,
A drive apparatus having a coaxial shaft arrangement which comprises a plurality of drive shafts which are arranged coaxially to one another at least regionally, with the axis of rotation of each drive shaft lying on a common rotational drive axis; and having an electric drive motor which comprises a rotor arrangement which comprises a plurality of rotors arranged coaxially to one another and/or behind one another at least regionally, with the axis of rotation of each rotor lying on the common rotational drive axis and forming one of the drive shafts or being connected to one of the drive shafts, wherein the drive motor can be controlled such that the rotors can be driven independently of one another, characterized in that the drive shafts are each arranged at the same side of the rotors.
A wind turbine blade, comprising: a first and a second blade component (10, 12) connected with each other in an overlap region by thermal welding, a resistive element arranged between the first and second blade components (10, 12) in the overlap region as a remnant of the thermal welding, characterized by the resistive element having a first and a second terminal (31, 32), a lightning conductor electrically connected with each of the first and second terminals (31, 32), and a surge protection device, wherein one of the first and second terminals (31, 32) is electrically connected with the lightning conductor via the surge protection device. a first and a second blade component (10, 12) connected with each other in an overlap region by thermal welding, a resistive element arranged between the first and second blade components (10, 12) in the overlap region as a remnant of the thermal welding, characterized by the resistive element having a first and a second terminal (31, 32), a lightning conductor electrically connected with each of the first and second terminals (31, 32), and a surge protection device, wherein one of the first and second terminals (31, 32) is electrically connected with the lightning conductor via the surge protection device.
A computer system (100, 300) for automatically overclocking, comprising: an overclocking element (130, 350) having a signal standard; a detecting circuit (110, 310) for acquiring an input/output (I/O) signal (Ds) of the overclocking element (130, 350), and detecting a reference clock (Rs) and the I/O signal and obtaining a phase difference between the reference clock (Rs) and the I/O signal, wherein the signal standard comprises the setting of a rated setup time of the I/O signal (Ds) and the setting of a rated hold time of the I/O signal (Ds), wherein the rated setup time and the rated hold time in the signal standard are respectively a minimal setup time and a minimal hold time for normally reading the I/O signal (Ds); and a basic input/output system (BIOS) (120, 320) configured to work out an I/O setup time of the I/O signal (Ds) and an I/O hold time of the I/O signal (Ds) according to the phase difference, compare the I/O setup time with the rated setup time and compare the I/O hold time with the rated hold time, thus getting a comparing result, and increase a frequency of the reference clock (Rs) to make the I/O setup time closest to but not less than the rated setup time and to make the I/O hold time closest to but not less than the rated hold time according to the comparing result, to maximize the frequency of the reference clock; wherein the reference clock is an input signal of the overclocking element (130, 350). an overclocking element (130, 350) having a signal standard; a detecting circuit (110, 310) for acquiring an input/output (I/O) signal (Ds) of the overclocking element (130, 350), and detecting a reference clock (Rs) and the I/O signal and obtaining a phase difference between the reference clock (Rs) and the I/O signal, wherein the signal standard comprises the setting of a rated setup time of the I/O signal (Ds) and the setting of a rated hold time of the I/O signal (Ds), wherein the rated setup time and the rated hold time in the signal standard are respectively a minimal setup time and a minimal hold time for normally reading the I/O signal (Ds); and a basic input/output system (BIOS) (120, 320) configured to work out an I/O setup time of the I/O signal (Ds) and an I/O hold time of the I/O signal (Ds) according to the phase difference, compare the I/O setup time with the rated setup time and compare the I/O hold time with the rated hold time, thus getting a comparing result, and increase a frequency of the reference clock (Rs) to make the I/O setup time closest to but not less than the rated setup time and to make the I/O hold time closest to but not less than the rated hold time according to the comparing result, to maximize the frequency of the reference clock; wherein the reference clock is an input signal of the overclocking element (130, 350).
A wafer container (20, 300) for receiving and transporting bonded wafers, the wafer container (20, 300) comprising: a container portion (30, 302) including an open front defining an open interior and a back wall having an inside surface; a door (32, 304) that closes the open front defining the open interior, the door (32, 304) having an inside surface; a wafer support (82, 88) attached to one of the inside surface of the front door (32, 304) and the inside surface of the back wall, the wafer support (82, 88) having a plurality of pairs of wafer edge engagement portions (222, 330, 356) having a first wafer edge engagement portion and a second wafer edge engagement portion, each wafer edge engagement portion defining a recess having a primary seating position, each of the wafer edge engagement portions (222, 330, 356) comprised of a first polymeric material, wherein an edge of a wafer is in the primary seating position when the wafer container (20, 300) is not in a shock condition, the wafer support (82, 88) further including at least one shock deflection region axially offset from each primary seating position, each of the at least one shock deflection region having a shock deflection contact portion positioned to contact a wafer when the wafer container (20, 300) is in a shock condition, wherein the shock deflection contact portion is comprised of a second polymeric material, the wafer container (20, 300) being characterized in that the second polymeric material is softer than the first polymeric material of the wafer edge engagement portions (222, 330, 356). a container portion (30, 302) including an open front defining an open interior and a back wall having an inside surface; a door (32, 304) that closes the open front defining the open interior, the door (32, 304) having an inside surface; a wafer support (82, 88) attached to one of the inside surface of the front door (32, 304) and the inside surface of the back wall, the wafer support (82, 88) having a plurality of pairs of wafer edge engagement portions (222, 330, 356) having a first wafer edge engagement portion and a second wafer edge engagement portion, each wafer edge engagement portion defining a recess having a primary seating position, each of the wafer edge engagement portions (222, 330, 356) comprised of a first polymeric material, wherein an edge of a wafer is in the primary seating position when the wafer container (20, 300) is not in a shock condition, the wafer support (82, 88) further including at least one shock deflection region axially offset from each primary seating position, each of the at least one shock deflection region having a shock deflection contact portion positioned to contact a wafer when the wafer container (20, 300) is in a shock condition, wherein the shock deflection contact portion is comprised of a second polymeric material,