mhurhangee/ep-ind-claims huggingface dataset:
A butene-1 polymer composition having MFR values of from 400 to 2000 g/10 min., measured according to ISO 1133 at 190°C with a load of 2.16 kg, comprising: A) a butene-1 homopolymer or a copolymer of butene-1 with one or more comonomers selected from ethylene and propylene, having a copolymerized comonomer content (C A) of up to 5% by mole; B) a copolymer of butene-1 with one or more comonomers selected from ethylene and propylene, having a copolymerized comonomer content (C B) of from 6% to 25% by mole; said composition having a total copolymerized comonomer content from 5% to 18% by mole, referred to the sum of A) and B), and a content of fraction soluble in xylene at 0°C of 65% by weight or more, determined on the total weight of A) and B). A) a butene-1 homopolymer or a copolymer of butene-1 with one or more comonomers selected from ethylene and propylene, having a copolymerized comonomer content (C A) of up to 5% by mole; B) a copolymer of butene-1 with one or more comonomers selected from ethylene and propylene, having a copolymerized comonomer content (C B) of from 6% to 25% by mole;
A bushing assembly for a track assembly, comprising a first end element; a second end element; and a central element positioned between the first end element and the second end element, wherein the central element is interference fit or positioned between the first end element and the second end element, and wherein the central element includes a greater hardness than the first and second end elements, wherein the first end element, the second end element, and the central element form a bushing with a longitudinal opening extending longitudinally through the bushing, characterised in that the first end element includes a first inner extension, the second end element includes a second inner extension, and the first inner extension and the second inner extension are complementary such that the first inner extension and the second inner extension at least partially overlap over a longitudinal length of the bushing assembly within the central element. a first end element; a second end element; and a central element positioned between the first end element and the second end element, wherein the central element is interference fit or positioned between the first end element and the second end element, and wherein the central element includes a greater hardness than the first and second end elements, wherein the first end element, the second end element, and the central element form a bushing with a longitudinal opening extending longitudinally through the bushing, characterised in that the first end element includes a first inner extension, the second end element includes a second inner extension, and the first inner extension and the second inner extension are complementary such that the first inner extension and the second inner extension at least partially overlap over a longitudinal length of the bushing assembly within the central element.
A conjugate comprising one, two, three, four, five, six, seven, or eight branched water-soluble poly(ethylene glycol) polymers, covalently attached via a releasable carbamate linkage to an amino group of an interleukin-2 moiety, each branched water-soluble poly(ethylene glycol) polymer having a total weight average molecular weight in a range of from 500 daltons to 100,000 daltons, wherein, upon release, the branched water-soluble poly(ethylene glycol) polymer detaches from the interleukin-2 moiety in vivo without leaving a fragment attached to the interleukin-2 moiety, the conjugate having a formula wherein POLY 1 is a first poly(ethylene glycol); POLY 2 is a second poly(ethylene glycol); X 1 is a first spacer moiety; X 2 is a second spacer moiety; Hα is an ionizable hydrogen atom; R 1 is H or an organic radical; R 2 is H or an organic radical; (a) is either zero or one; (b) is either zero or one; R e1, when present, is a first electron altering group; R e2, when present, is a second electron altering group; Y 1 is O; Y 2 is O; n is an integer from 1-8; and (IL-2) is an interleukin-2 moiety having an amino acid sequence of SEQ ID NO:3 or having 95% or greater sequence identity to SEQ ID NO:3.
Method for operating a household appliance, comprising a casing, at least one water circuit, and at least one valve associated to said water circuit, whereby said appliance performs at least one process in which water flows into and/or from said water circuit, said at least one valve is configured to allow and/or prevent water flow in said water circuit inside said appliance through its activation or its deactivation, characterised in that during a predetermined period an anti-stucking procedure is performed in which in an alternating sequence said valve is at least one time activated and subsequently deactivated or at least one time deactivated and subsequently activated, whereby said procedure is performed after a triggering event, said triggering event being an alarm and/or a detected water leakage, or said procedure is performed after the last deactivation of the valve has been performed, in case of a programmed sequence of activation and deactivation of the valve, and in that a quick alternation from the activation and the deactivation state or vice versa is performed to unblock the movable part(s) of the valve from its seat, said quick alternation being an alternation between the activation and deactivation state or vice versa in such a time that the reached state is not maintained as long as to stabilize the fluid dynamic state internally to the valve, whereby each alternation from the activation and the deactivation state is obtained by the change of the state immediately after the previous state has been reached.
Heatsink for a luminaire, said heatsink comprising • a first portion being adapted for arranging a light source driver, an emergency lighting unit or a housing for accommodating a light source driver or an emergency lighting unit, and • a second portion being integrally formed with the first portion and adapted for arranging a light source, wherein at least some cooling fins extending from the first portion to the second portion are interrupted by a gap, characterized in that the heatsink further comprises support elements extending from the first portion of the heatsink to the second portion, wherein the support elements comprise a cut which splits each support element in two portions (20a, 20b) and wherein the cut diagonally extends through the support element. • a first portion being adapted for arranging a light source driver, an emergency lighting unit or a housing for accommodating a light source driver or an emergency lighting unit, and • a second portion being integrally formed with the first portion and adapted for arranging a light source,
A cutting insert (100, 100', 101), comprising: an upper surface including: a rake surface; and an upper abutment portion defining an upper plane; a peripheral surface including a front surface, a rear surface, and two insert side surfaces extending therebetween, the front surface having a relief surface; and a cutting edge formed at the intersection of the rake surface and the relief surface, and characterised in that there is a bottom surface including: a first bottom abutment portion defining a first bottom plane, forming a first angle (α) with the upper plane; a second bottom abutment portion defining a second bottom plane parallel to the first bottom plane and spaced apart therefrom; and a stopper abutment portion located between the first and second bottom abutment portions (110, 112); wherein a reference plane perpendicular to the upper plane and passing through the upper abutment portion, intersects the first and second bottom planes (P1,P2) at first and second intersection lines (I1, 12), respectively, the first and second intersection lines (I1, I2) being spaced apart from the first and second bottom abutment portions (110, 112), respectively. an upper surface including: a rake surface; and an upper abutment portion defining an upper plane; a rake surface; and an upper abutment portion defining an upper plane; a peripheral surface including a front surface, a rear surface, and two insert side surfaces extending therebetween, the front surface having a relief surface; and a cutting edge formed at the intersection of the rake surface and the relief surface, and characterised in that there is a bottom surface including: a first bottom abutment portion defining a first bottom plane, forming a first angle (α) with the upper plane; a second bottom abutment portion defining a second bottom plane parallel to the first bottom plane and spaced apart therefrom; and a stopper abutment portion located between the first and second bottom abutment portions (110, 112); a first bottom abutment portion defining a first bottom plane, forming a first angle (α) with the upper plane; a second bottom abutment portion defining a second bottom plane parallel to the first bottom plane and spaced apart therefrom; and a stopper abutment portion located between the first and second bottom abutment portions (110, 112);
A manufacturing method of an impeller which includes a disc, a cover opposed to the disc, a plurality of blades provided between the disc and the cover, and a plurality of passages formed between the disc and the cover, each of the passages having an inlet formed on a surface of the cover of the impeller and an outlet formed on an outer peripheral surface of the impeller, and the direction of each of the passages being changed so as to follow a radial direction of the impeller as it proceeds from the inlet to the outlet, and a portion around an inner periphery of the disc which is a bond part bonded with the blade is formed with a curved surface, the manufacturing method comprising: forming the plurality of blades integrally on a blade attachment surface (2a; 4a) of one of the disc and the cover; placing the cover on a floor so as to face up the blade attachment surface of the cover; disposing the disc on the cover so as to face down the blade attachment surface of the disc; and bonding the plurality of blades to the blade attachment surface (4a; 2a) of the other of the disc and the cover which is not formed integrally with the plurality of blades by using a bonding material; characterized in that a protruding portion or a recess portion is provided near an inner peripheral bond part end where the passage is curved, in a bond part with the blades, on the blade attachment surface of the cover so as to prevent the bonding material from spilling. forming the plurality of blades integrally on a blade attachment surface (2a; 4a) of one of the disc and the cover; placing the cover on a floor so as to face up the blade attachment surface of the cover; disposing the disc on the cover so as to face down the blade attachment surface of the disc; and bonding the plurality of blades to the blade attachment surface (4a; 2a) of the other of the disc and the cover which is not formed integrally with the plurality of blades by using a bonding material; characterized in that a protruding portion or a recess portion is provided near an inner peripheral bond part end where the passage is curved, in a bond part with the blades, on the blade attachment surface of the cover so as to prevent the bonding material from spilling.
A method in predicting the life cycle of a splice comprising: a) establishing a baseline over time for a splice of predetermined construction based on deviations in a signal curve for the splice in a vicinity of a zero crossing point of the signal curve using a sine curve and a first ratio of amplitude at a time of monitoring and an amplitude at a start time and a period change ratio based on a period at the time of monitoring and the period at the start time; b) monitoring an in-service splice in the vicinity of the zero crossing point for a signal of the in-service splice using the deviations used in step (a) for the signal of the in-service splice; and c) comparing the baseline of step (a) to information from step (b) to determine a degradation for the in-service splice and a decay rate curve, the decay rate curve providing an indication of a percentage of useful life remaining and time to failure for the in-service splice, the decay rate curve providing a guide for monitoring other splices for useful life and time to failure. a) establishing a baseline over time for a splice of predetermined construction based on deviations in a signal curve for the splice in a vicinity of a zero crossing point of the signal curve using a sine curve and a first ratio of amplitude at a time of monitoring and an amplitude at a start time and a period change ratio based on a period at the time of monitoring and the period at the start time; b) monitoring an in-service splice in the vicinity of the zero crossing point for a signal of the in-service splice using the deviations used in step (a) for the signal of the in-service splice; and c) comparing the baseline of step (a) to information from step (b) to determine a degradation for the in-service splice and a decay rate curve, the decay rate curve providing an indication of a percentage of useful life remaining and time to failure for the in-service splice, the decay rate curve providing a guide for monitoring other splices for useful life and time to failure.
A uniform and controlled sinking system for submerging a raft or cage at user's discretion in case of adverse conditions that could jeopardize the fish production and the corresponding infrastructure, the system comprises - a raft or cage configured for buoyancy, - a lower ring bounded to the lower part of the raft by means of a mesh, - a distribution ring configured for uniformly submerging the system, which is attached to the lower ring by means of ropes or cables at an equal distance between them and said distribution ring having an eyebolt in its lower part, to which one rope, cable or chain being connected, this rope, cable or chain is connecting the distribution ring to a cylinder, which in its upper part is closed and maintains an air chamber and has an open bottom through which the water can enter, and the cylinder is connectable with the sea surface via a hose configured for injecting air into the air chamber of the cylinder, - a dead weight configured for maintaining said raft submerged, which is connected to the bottom of the cylinder by means of a chain. - a raft or cage configured for buoyancy, - a lower ring bounded to the lower part of the raft by means of a mesh, - a distribution ring configured for uniformly submerging the system, which is attached to the lower ring by means of ropes or cables at an equal distance between them and - a dead weight configured for maintaining said raft submerged, which is connected to the bottom of the cylinder by means of a chain.
A process for purifying a compound of formula 1, comprising the following steps: a) adding an acid to an aqueous solution of the compound of formula 1, including salts thereof so as to obtain a pH ≤ 3 whereby a slurry is obtained; and b) filtering the slurry and at least one time washing the obtained precipitate with a mixture of water and a water miscible low boiling organic solvent, the mixture having a water: water miscible low boiling organic solvent weight ratio of 1: 1.5 to 1: 5; and c) dissolving the precipitate obtained in step b) in water to obtain an aqueous solution; and d) filtering of the solution obtained in step c) over a nanofiltration membrane having a Molecular Weight Cut Off in the range from 150 to 500 and wherein optionally, between step c) and step d) the pH of the aqueous solution is adjusted to a pH value in the pH range as specified by the manufacturer of the nanofiltration membrane. a) adding an acid to an aqueous solution of the compound of formula 1, including salts thereof so as to obtain a pH ≤ 3 whereby a slurry is obtained; and b) filtering the slurry and at least one time washing the obtained precipitate with a mixture of water and a water miscible low boiling organic solvent, the mixture having a water: water miscible low boiling organic solvent weight ratio of 1: 1.5 to 1: 5; and c) dissolving the precipitate obtained in step b) in water to obtain an aqueous solution; and d) filtering of the solution obtained in step c) over a nanofiltration membrane having a Molecular Weight Cut Off in the range from 150 to 500 and wherein optionally, between step c) and step d) the pH of the aqueous solution is adjusted to a pH value in the pH range as specified by the manufacturer of the nanofiltration membrane.
A planar patch clamp device for analyzing a neuron network, comprising: an electrical insulating plate with a neuron network-forming side and a second surface side on the opposite side provided with at least one through-hole allowing communication between both sides and having a diameter which is such that the neurons cannot pass through; liquid pool sections and formed on each side of the electrical insulating plate surface, which enable holding cell culture medium, being connected together by the fine(s) through hole; an electrode section provided on the neuron network-forming side disposed to be electrically conductive to the cell culture medium; a second electrode section provided on the second surface side disposed to be electrically conductive to the conducting liquid; wherein (a) cell plating section surrounded by a plurality of protrusions is formed on the first surface so that the protrusions restrict the movement of cells, but allow the formation of a neuron network, (b) the through-hole is arranged in the cell plating section, (c) plate surface forming the bottom of the cell plating section is coated with an extracellular matrix-forming substance, and (d) the diameter of the cell plating section defined by the plurality of protrusions is a size enables to accommodate one to several cell bodies. an electrical insulating plate with a neuron network-forming side and a second surface side on the opposite side provided with at least one through-hole allowing communication between both sides and having a diameter which is such that the neurons cannot pass through; liquid pool sections and formed on each side of the electrical insulating plate surface, which enable holding cell culture medium, being connected together by the fine(s) through hole; an electrode section provided on the neuron network-forming side disposed to be electrically conductive to the cell culture medium; a second electrode section provided on the second surface side disposed to be electrically conductive to the conducting liquid; wherein (a) cell plating section surrounded by a plurality of protrusions is formed on the first surface so that the protrusions restrict the movement of cells, but allow the formation of a neuron network, (b) the through-hole is arranged in the cell plating section, (c) plate surface forming the bottom of the cell plating section is coated with an extracellular matrix-forming substance, and (d) the diameter of the cell plating section defined by the plurality of protrusions is a size enables to accommodate one to several cell bodies. (a) cell plating section surrounded by a plurality of protrusions is formed on the first surface so that the protrusions restrict the movement of cells, but allow the formation of a neuron network, (b) the through-hole is arranged in the cell plating section, (c) plate surface forming the bottom of the cell plating section is coated with an extracellular matrix-forming substance, and (d) the diameter of the cell plating section defined by the plurality of protrusions is a size enables to accommodate one to several cell bodies.
A Cucurbita plant comprising a Cmv-2 gene conferring Cucumber Mosaic Virus resistance to said Cucurbita plant, wherein said Cmv-2 gene is obtainable from a plant of C. moschata cv. Seminole pumpkin, wherein, when said Cucurbita plant is crossed with a plant of inbred line 90-3588, 100% of F1 plants resulting from said cross are resistant to CMV, and 100% of said F1 plants produce 100% of F2 progeny plants resistant to CMV, wherein said Cucurbita plant is homozygous for a Cmv-2 gene, wherein said plant is not a plant of C. moschata cv. Seminole pumpkin, wherein said plant is male sterile, wherein resistance to CMV is monogenic and wherein said Cmv-2 gene is obtainable from a plant of line 90-3588, representative seed of which being deposited under accession number NCIMB 41369.
A growth hormone releasing hormone (GHRH) analog comprising a peptide having the sequence set forth in formula (SEQ ID NO: 1): wherein: X1 is Tyr, His, N-methyl Tyr or Desamino Tyr; X2 is Ala, D-Ala, Ser or alpha aminoisobutyric acid (Aib); X8 is Asn, Asp, Ala, Gln, Ser or Aib; X9 is Cys conjugated to a PEG polymer of less than or equal to 5 kDa; X11 is Arg or L-Homoarginine (Har); X12 is Lys or Orn; X15 is Gly or Ala; X18 is Ser or Ala; X20 is Arg or Har; X21 is Lys or Orn; X22 is Leu, Val or Ala; X24 is Gln; X25 is Asp or Ala; X26 is Ile or Ala; X27 is Met, Leu or Norleucine; X28 is Ser or Ala; X29 is Lys, Arg, Orn, Har or Agmatine; and X30 is an NH 2 group or Asn-NH 2; or a pharmaceutically acceptable salt thereof, wherein optionally one of X22, X24 or X28 is Cys conjugated to a PEG polymer of less than or equal to 5 kDa. X1 is Tyr, His, N-methyl Tyr or Desamino Tyr; X2 is Ala, D-Ala, Ser or alpha aminoisobutyric acid (Aib); X8 is Asn, Asp, Ala, Gln, Ser or Aib; X9 is Cys conjugated to a PEG polymer of less than or equal to 5 kDa; X11 is Arg or L-Homoarginine (Har); X12 is Lys or Orn; X15 is Gly or Ala; X18 is Ser or Ala; X20 is Arg or Har; X21 is Lys or Orn; X22 is Leu, Val or Ala; X24 is Gln; X25 is Asp or Ala; X26 is Ile or Ala; X27 is Met, Leu or Norleucine; X28 is Ser or Ala; X29 is Lys, Arg, Orn, Har or Agmatine; and X30 is an NH 2 group or Asn-NH 2;
An LED unit comprising: a string of LED modules including: a pair of terminal LED modules (6, 8) at opposite ends of said string, each of said terminal LED modules comprising two external terminals (1, 2; 3, 4) connected to an anode (10; 12) and cathode (14; 16) respectively of the LED module; and an intermediate LED module having an anode connected to the cathode of one of the terminal LED modules and a cathode connected to the anode of the other of the terminal LED modules, such that any combination of said LED modules may be switched on by providing a current between a selected combination of said external terminals (1, 2; 3, 4). a string of LED modules including: a pair of terminal LED modules (6, 8) at opposite ends of said string, each of said terminal LED modules comprising two external terminals (1, 2; 3, 4) connected to an anode (10; 12) and cathode (14; 16) respectively of the LED module; and an intermediate LED module having an anode connected to the cathode of one of the terminal LED modules and a cathode connected to the anode of the other of the terminal LED modules, such that any combination of said LED modules may be switched on by providing a current between a selected combination of said external terminals (1, 2; 3, 4). a pair of terminal LED modules (6, 8) at opposite ends of said string, each of said terminal LED modules comprising two external terminals (1, 2; 3, 4) connected to an anode (10; 12) and cathode (14; 16) respectively of the LED module; and an intermediate LED module having an anode connected to the cathode of one of the terminal LED modules and a cathode connected to the anode of the other of the terminal LED modules, such that any combination of said LED modules may be switched on by providing a current between a selected combination of said external terminals (1, 2; 3, 4).