mhurhangee/ep-ind-claims huggingface dataset:
A filamentous fungal cell, which is a Trichoderma cell, preferably, Trichoderma reesei, which produces a heterologous glycoprotein with mammalian-like N-glycans, comprising: i. the deletion of at least the following endogenous proteases genes: pep1, tsp1, slp1, gap1, gap2, pep4, and pep3; ii. a polynucleotide encoding a heterologous catalytic subunit of oligosaccharyl transferase selected from Leishmania oligosaccharyl transferase catalytic subunits; iii. a recombinant polynucleotide for increasing α1, 2 mannosidase activity selected from the group consisting T. reesei α1,2 mannosidase encoding gene or T. reesei α1,2 mannosidase encoding gene fused to HDEL targeting sequence or microalgae α1,2 mannosidase encoding gene; and, iv. the deletion of OCH1 activity and EndoT activity, or the deletion of PMT1 activity and EndoT activity; v. a recombinant polynucleotide encoding said heterologous glycoprotein wherein the N-glycosylation site occupancy of the heterologous glycoprotein is at least 95%, and wherein at least 90% (mol%), preferably at least 95% of the total neutral N-glycans of said produced heterologous glycoprotein are from the group consisting of: • Manα3[Manα6(Manα3)Manα6]Manβ4GlcNAβ4GlcNAc (Man5 glycoform); • GlcNAcβ2Manα3[Manα6(Manα3)Manα6]Manβ4GlcNAβ4GlcNAc (GlcNAcMan5 glycoform); • Manα6(Manα3)Manβ4GlcNAβ4GlcNAc (Man3 glycoform); • Manα6(GlcNAcβ2Manα3)Manβ4GlcNAβ4GlcNAc (GlcNAcMan3 glycoform); • complex type N-glycans selected from the G0, G1, or G2 glycoform; and, • complex type fucosylated N-glycans FG0, FG1, or FG2 glycoform. i. the deletion of at least the following endogenous proteases genes: pep1, tsp1, slp1, gap1, gap2, pep4, and pep3; ii. a polynucleotide encoding a heterologous catalytic subunit of oligosaccharyl transferase selected from Leishmania oligosaccharyl transferase catalytic subunits; iii. a recombinant polynucleotide for increasing α1, 2 mannosidase activity selected from the group consisting T. reesei α1,2 mannosidase encoding gene or T. reesei α1,2 mannosidase encoding gene fused to HDEL targeting sequence or microalgae α1,2 mannosidase encoding gene; and, iv. the deletion of OCH1 activity and EndoT activity, or the deletion of PMT1 activity and EndoT activity; v. a recombinant polynucleotide encoding said heterologous glycoprotein • Manα3[Manα6(Manα3)Manα6]Manβ4GlcNAβ4GlcNAc (Man5 glycoform); • GlcNAcβ2Manα3[Manα6(Manα3)Manα6]Manβ4GlcNAβ4GlcNAc (GlcNAcMan5 glycoform); • Manα6(Manα3)Manβ4GlcNAβ4GlcNAc (Man3 glycoform); • Manα6(GlcNAcβ2Manα3)Manβ4GlcNAβ4GlcNAc (GlcNAcMan3 glycoform); • complex type N-glycans selected from the G0, G1, or G2 glycoform; and, • complex type fucosylated N-glycans FG0, FG1, or FG2 glycoform.
Coating material composition comprising - at least one polyhydroxyl group-containing component, - at least one polyisocyanate group-containing component, - at least one zinc-imidazole-carboxylate complex preparable by reacting at least one Zn biscarboxylate with one or more imidazoles of the general formula in which R 1 is an acyclic or cyclic, saturated or unsaturated hydrocarbon radical, an aromatic hydrocarbon radical or a radical R v -aryl, where R v is an alkylene radical and aryl is an aromatic radical, and where all of the aforementioned radicals may contain heteroatoms, R 2, R 3 and R 4 independently of one another are hydrogen, an acyclic or cyclic, saturated or unsaturated hydrocarbon radical, an aromatic hydrocarbon radical or a radical R v -aryl, where R v is an alkylene radical and aryl is an aromatic radical, and where all of the aforementioned radicals may contain heteroatoms, with the proviso that zinc-(1-methylimidazole)-bis(2-ethylhexanoate) complexes which are obtainable by reacting zinc bis(2-ethylhexanoate) with 1-methylimidazole in a molar ratio of 1 to ≤ 2.2 are excluded, and - at least one monomeric aromatic carboxylic acid in which the carboxyl group is in conjugation to a pi electron system. - at least one polyhydroxyl group-containing component, - at least one polyisocyanate group-containing component, - at least one zinc-imidazole-carboxylate complex preparable by reacting at least one Zn biscarboxylate with one or more imidazoles of the general formula in which R 1 is an acyclic or cyclic, saturated or unsaturated hydrocarbon radical, an aromatic hydrocarbon radical or a radical R v -aryl, where R v is an alkylene radical and aryl is an aromatic radical, and where all of the aforementioned radicals may contain heteroatoms, R 2, R 3 and R 4 independently of one another are hydrogen, an acyclic or cyclic, saturated or unsaturated hydrocarbon radical, an aromatic hydrocarbon radical or a radical R v -aryl, where R v is an alkylene radical and aryl is an aromatic radical, and where all of the aforementioned radicals may contain heteroatoms, with the proviso that zinc-(1-methylimidazole)-bis(2-ethylhexanoate) complexes which are obtainable by reacting zinc bis(2-ethylhexanoate) with 1-methylimidazole in a molar ratio of 1 to ≤ 2.2 are excluded, and - at least one monomeric aromatic carboxylic acid in which the carboxyl group is in conjugation to a pi electron system.
Portable electronic object provided with a case including a middle part closed by a back cover and by a glass and a bezel fixed to the middle part, said case containing at least one electronic module formed of a printed circuit board on which is fixed at least one microcontroller sending information to display means, said object further including touch control means including at least one flexible base element on which at least one electrode is structured, said electrode being electrically connected to the microcontroller by a conductive track, characterized in that the base element is arranged so as to be deformed in order to adapt to the shapes of the portable object and in that the base element is fixed and directly connected to said printed circuit board.
A vehicle comprising: a battery pack housing a battery module; a cover plate attached to a side surface of the battery pack; and a battery cooling structure comprising: a plurality of cooling passages (2a, 2b, 2c) for taking cooling air into the battery pack, the plurality of cooling passages (2a, 2b, 2c) being formed on a surface of the cover plate; and a connection passage (2d, 2e, 2f, 2g, 2h, 2i) that is formed in a direction intersecting with the plurality of cooling passages (2a, 2b, 2c) on the surface of the cover plate and that connects the plurality of cooling passages (2a, 2b, 2c) with one another to allow interchange of the cooling air, wherein the battery pack is arranged in a center console box between a driver seat and a front passenger seat in the vehicle, the plurality of cooling passages (2a, 2b, 2c) extend in parallel with one another and in a direction vertical to a floor surface, and partial portions of the cooling passages (2a, 2b, 2c) on a floor surface side are open. a battery pack housing a battery module; a cover plate attached to a side surface of the battery pack; and a battery cooling structure comprising: a plurality of cooling passages (2a, 2b, 2c) for taking cooling air into the battery pack, the plurality of cooling passages (2a, 2b, 2c) being formed on a surface of the cover plate; and a connection passage (2d, 2e, 2f, 2g, 2h, 2i) that is formed in a direction intersecting with the plurality of cooling passages (2a, 2b, 2c) on the surface of the cover plate and that connects the plurality of cooling passages (2a, 2b, 2c) with one another to allow interchange of the cooling air, a plurality of cooling passages (2a, 2b, 2c) for taking cooling air into the battery pack, the plurality of cooling passages (2a, 2b, 2c) being formed on a surface of the cover plate; and a connection passage (2d, 2e, 2f, 2g, 2h, 2i) that is formed in a direction intersecting with the plurality of cooling passages (2a, 2b, 2c) on the surface of the cover plate and that connects the plurality of cooling passages (2a, 2b, 2c) with one another to allow interchange of the cooling air, wherein the battery pack is arranged in a center console box between a driver seat and a front passenger seat in the vehicle, the plurality of cooling passages (2a, 2b, 2c) extend in parallel with one another and in a direction vertical to a floor surface, and partial portions of the cooling passages (2a, 2b, 2c) on a floor surface side are open.
A vehicle comprising: an engine; a tilting sensor configured to detect that a body of the vehicle is tilted a predetermined angle or larger; a driving state sensor (41 to 48) configured to detect a driving state of the vehicle using a component other than the tilting sensor; and a determiner configured to determine whether or not to stop the engine, based on a signal received from the tilting sensor, and a signal received from the driving state sensor (41 to 48), wherein in a case where the determiner detects that the body is tilted the predetermined angle or larger by using the tilting sensor and then starts to detect a predetermined signal output from the driving state sensor (41 to 48), the determiner determines that the engine should be stopped when the determiner detects that the predetermined signal continues to be output for a predetermined time period, and the determiner determines that the engine should not be stopped when the determiner detects that the predetermined signal does not continue to be output for the predetermined time period. an engine; a tilting sensor configured to detect that a body of the vehicle is tilted a predetermined angle or larger; a driving state sensor (41 to 48) configured to detect a driving state of the vehicle using a component other than the tilting sensor; and a determiner configured to determine whether or not to stop the engine, based on a signal received from the tilting sensor, and a signal received from the driving state sensor (41 to 48), the determiner determines that the engine should be stopped when the determiner detects that the predetermined signal continues to be output for a predetermined time period, and the determiner determines that the engine should not be stopped when the determiner detects that the predetermined signal does not continue to be output for the predetermined time period.
An ophthalmologic apparatus, comprising: an acquisition unit including an optical scanner capable of deflecting light in a predetermined deflection angle range and configured to acquire data of a subject's eye by performing A-scan on the subject's eye using optical coherence tomography by measurement light deflected by the optical scanner; and a controller configured to cause the acquisition unit to perform A-scan based on a deflection operation state of the optical scanner, wherein the controller is configured to cause the acquisition unit to perform A-scan depending on a deflection angle of the optical scanner and is configured to cause the acquisition unit to perform A-scan so that intervals between the deflection angles are substantially equal; characterized in that the controller is configured: to acquire operation information representing a deflection angle of the optical scanner; to determine whether or not the deflection angle is a predetermined deflection angle based on the acquired operation information; and to cause the acquisition unit to perform A-scan when it is determined that the deflection angle is the predetermined deflection angle. an acquisition unit including an optical scanner capable of deflecting light in a predetermined deflection angle range and configured to acquire data of a subject's eye by performing A-scan on the subject's eye using optical coherence tomography by measurement light deflected by the optical scanner; and a controller configured to cause the acquisition unit to perform A-scan based on a deflection operation state of the optical scanner, wherein the controller is configured to cause the acquisition unit to perform A-scan depending on a deflection angle of the optical scanner and is configured to cause the acquisition unit to perform A-scan so that intervals between the deflection angles are substantially equal; characterized in that the controller is configured: to acquire operation information representing a deflection angle of the optical scanner; to determine whether or not the deflection angle is a predetermined deflection angle based on the acquired operation information; and to cause the acquisition unit to perform A-scan when it is determined that the deflection angle is the predetermined deflection angle. to acquire operation information representing a deflection angle of the optical scanner; to determine whether or not the deflection angle is a predetermined deflection angle based on the acquired operation information; and to cause the acquisition unit to perform A-scan when it is determined that the deflection angle is the predetermined deflection angle.
Multilayer laminate comprising a facestock material, consisting of a film or paper, and at least two adhesive substance layers (12, 14), wherein the adhesive substance layers (12, 14) each comprise an adhesive substance composition, characterised in that an intermediate layer is arranged between the adhesive substance layers (12, 14), wherein the intermediate layer comprises an intermediate layer composition with one or more binders, and that the intermediate layer has a glass transition temperature measured to ASTM D 3418/82 of less than 0°C, wherein the binders are elastomers and the at least one binder of the intermediate layer is not tacky at a room temperature of 21°C and the intermediate layer is not formed so as to be adhesive.
A method, comprising: determining (1120; 1220), at an evolved Node B, eNB, to grant resources on a long term evolution Unlicensed secondary cell, LTE-U SCell, carrier (130, 720, 820) for an uplink, UL, transmission; transmitting (1130; 1230) from the eNB and on an LTE primary cell, PCell, carrier (710, 810), the determined scheduling grant for the UL transmission on a packet data shared channel on the LTE-U SCell carrier, wherein the LTE PCell carrier is in a licensed frequency spectrum; broadcasting (1140; 1240), from the eNB, at least one of a Clear to Send, CTS, message (142, 1020, 1140, 1240) or a Request to Send, RTS, message (142, 1020, 1140, 1240) on the LTE-U SCell carrier, wherein the at least one of the CTS message or the RTS message includes a duration field, the duration field indicating a specific number of subframes for the scheduled UL transmission for clearing the LTE-U SCell carrier for the UL transmission during the specific number of subframes; and receiving (1150;1250) the UL transmission on the LTE-U SCell carrier. determining (1120; 1220), at an evolved Node B, eNB, to grant resources on a long term evolution Unlicensed secondary cell, LTE-U SCell, carrier (130, 720, 820) for an uplink, UL, transmission; transmitting (1130; 1230) from the eNB and on an LTE primary cell, PCell, carrier (710, 810), the determined scheduling grant for the UL transmission on a packet data shared channel on the LTE-U SCell carrier, wherein the LTE PCell carrier is in a licensed frequency spectrum; broadcasting (1140; 1240), from the eNB, at least one of a Clear to Send, CTS, message (142, 1020, 1140, 1240) or a Request to Send, RTS, message (142, 1020, 1140, 1240) on the LTE-U SCell carrier, wherein the at least one of the CTS message or the RTS message includes a duration field, the duration field indicating a specific number of subframes for the scheduled UL transmission for clearing the LTE-U SCell carrier for the UL transmission during the specific number of subframes; and receiving (1150;1250) the UL transmission on the LTE-U SCell carrier.
A method for refreshing a row hammer, comprising: determining a row hammer refresh instruction for a target word line; setting, according to the row hammer refresh instruction, a preset row hammer refresh signal to a valid state, wherein the valid state of the preset row hammer refresh signal indicates that the row hammer refresh instruction is performed in a first refresh period; and in response to detecting that the row hammer refresh instruction is not completed within the first refresh period, continuing the valid state of the preset row hammer refresh signal to a next refresh period of the first refresh period; and in response to detecting that the row hammer refresh instruction is completed, setting the preset row hammer refresh signal to an invalid state. determining a row hammer refresh instruction for a target word line; setting, according to the row hammer refresh instruction, a preset row hammer refresh signal to a valid state, wherein the valid state of the preset row hammer refresh signal indicates that the row hammer refresh instruction is performed in a first refresh period; and in response to detecting that the row hammer refresh instruction is not completed within the first refresh period, continuing the valid state of the preset row hammer refresh signal to a next refresh period of the first refresh period; and in response to detecting that the row hammer refresh instruction is completed, setting the preset row hammer refresh signal to an invalid state.
A pneumatic tire comprising a carcass extending from a tread portion through sidewall portions to bead portions, wherein the carcass is formed by arranging ribbon-shaped carcass ply pieces, in each of which a length in a tire circumferential direction is shorter than a length in a radial direction, in the tire circumferential direction, and each carcass ply piece includes a plurality of carcass cords arranged as warps along the radial direction, and a topping rubber covering the carcass cords, characterized in that the plurality of carcass cords is arranged without wefts, and in that the carcass cords include first cords and second cords having a twisting direction opposite to that of the first cords.
A solar thermal collector comprising a glass plate, an absorber, an apparatus for overheat prevention and a transparent insulation including thermal convection suppression, said insulation suppressing convective heat transfer between said glass plate and said absorber, characterized in that said absorber includes a spectrally selective coating with an emittance greater than 0.15 at wavelengths greater than a critical wavelength.
A suture button construct comprising: a dog-bone shaped suture button having body having a concavity, the body having four lobes and two slotted openings (14, 16) separated by a middle portion, each of the two slotted openings (14, 16) forming a slot extending from an outer circumference of the body between two neighboring lobes ofsaid four lobes to one of a plurality of apertures within the body, the slotted openings (14, 16) allowing a suture construct to pass through the elongated body, wherein the suture button construct comprises a suture construct passing through the plurality of apertures of the body, the suture construct being attached to the suture button, characterized in that the suture construct is a fused suture construct comprising at least two separate and independent suture strands or suture tapes connected together at a midpoint of each of the suture strands or tapes, resulting in multiple limbs (210a, 210b, 220a, 220b) of suture strands or tapes of equal length. a dog-bone shaped suture button having body having a concavity, the body having four lobes and two slotted openings (14, 16) separated by a middle portion, each of the two slotted openings (14, 16) forming a slot extending from an outer circumference of the body between two neighboring lobes ofsaid four lobes to one of a plurality of apertures within the body, the slotted openings (14, 16) allowing a suture construct to pass through the elongated body,
(clean copy) A method of manufacturing an organic photovoltaic cell comprising: preparing a substrate; forming a first electrode in one region of the substrate; forming an organic layer including a photoactive layer on an upper portion of the first electrode; performing surface treatment of the photoactive layer by a non-solvent; and forming a second electrode on the organic layer, wherein in the surface treatment by a non-solvent, the non-solvent is removed within 1 min after the non-solvent is applied, and wherein the photoactive layer includes an electron accepting material and an electron donating material, Wherein the non-solvent is one or more alcohols, and wherein the electron donating material is a polymer comprising a unit represented by the following Formula 6: wherein x is a mole fraction and a real number in the range of 0 < x < 1; y is a mole fraction and a real number in the range of 0 < y < 1; x+y=1; n is an integer ranging from 1 to 10,000; R10 to R12 are the same or different and are each independently hydrogen; a substituted or unsubstituted alkyl group; or a substituted or unsubstituted alkoxy group. preparing a substrate; forming a first electrode in one region of the substrate; forming an organic layer including a photoactive layer on an upper portion of the first electrode; performing surface treatment of the photoactive layer by a non-solvent; and forming a second electrode on the organic layer, wherein in the surface treatment by a non-solvent, the non-solvent is removed within 1 min after the non-solvent is applied, and wherein the photoactive layer includes an electron accepting material and an electron donating material, Wherein the non-solvent is one or more alcohols, and wherein the electron donating material is a polymer comprising a unit represented by the following Formula 6: wherein x is a mole fraction and a real number in the range of 0 < x < 1; y is a mole fraction and a real number in the range of 0 < y < 1; x+y=1; n is an integer ranging from 1 to 10,000; R10 to R12 are the same or different and are each independently hydrogen; a substituted or unsubstituted alkyl group; or a substituted or unsubstituted alkoxy group. x is a mole fraction and a real number in the range of 0 < x < 1; y is a mole fraction and a real number in the range of 0 < y < 1; x+y=1; n is an integer ranging from 1 to 10,000; R10 to R12 are the same or different and are each independently hydrogen; a substituted or unsubstituted alkyl group; or a substituted or unsubstituted alkoxy group.