An infection treatment system (10, 100) comprising: a first intramedullary rod (12, 112) configured for placement within an intramedullary canal, the first rod (12, 112) comprising a superior portion (26, 126) having a superior end (28, 128), an inferior portion (30, 130) having an inferior end (32, 132), and a shaft (34, 134) having a longitudinal axis therethrough and extending between the superior and inferior portions (26, 126, 30, 130), the shaft (34, 134) comprising a plurality of elongate angularly spaced channels (36, 136) extending substantially parallel to the longitudinal axis of the shaft (34, 134); a second intramedullary rod (14, 114) configured for placement within an intramedullary canal, the second rod (14, 114) comprising a superior portion (38, 138) having a superior end (40, 140), an inferior portion (42, 142) having an inferior end (44, 144), and a shaft (46, 146) having a longitudinal axis therethrough extending between the superior and inferior portions (38, 138, 42, 142), the shaft (46, 146) comprising a plurality of elongate angularly spaced channels (48, 148) extending substantially parallel to the longitudinal axis of the shaft (46, 146); and a fenestrated coupler (16, 116, 200) attached to the first and second rods (12, 112, 14, 114) in an operative configuration, the fenestrated coupler (16, 116, 200) having a superior face (50, 150), an inferior face (52, 152), an anterior face (54, 154), a posterior face (56, 156), a first lateral face (58, 158) and a second lateral face, at least one of the faces comprising at least one opening (60, 160) in fluid communication with at least a portion of the plurality of channels (26, 126, 48, 148) of the first and second rods (12, 112, 14, 114); characterised in that the superior face (50, 150) of the coupler (16, 116, 200) comprises a removable endplate (90, 190) and the inferior face (52, 152) comprises a removable endplate (92, 192), each of the endplates (90, 92, 190, 192) comprising a plurality of throughholes (95, 195). a first intramedullary rod (12, 112) configured for placement within an intramedullary canal, the first rod (12, 112) comprising a superior portion (26, 126) having a superior end (28, 128), an inferior portion (30, 130) having an inferior end (32, 132), and a shaft (34, 134) having a longitudinal axis therethrough and extending between the superior and inferior portions (26, 126, 30, 130), the shaft (34, 134) comprising a plurality of elongate angularly spaced channels (36, 136) extending substantially parallel to the longitudinal axis of the shaft (34, 134); a second intramedullary rod (14, 114) configured for placement within an intramedullary canal, the second rod (14, 114) comprising a superior portion (38, 138) having a superior end (40, 140), an inferior portion (42, 142) having an inferior end (44, 144), and a shaft (46, 146) having a longitudinal axis therethrough extending between the superior and inferior portions (38, 138, 42, 142), the shaft (46, 146) comprising a plurality of elongate angularly spaced channels (48, 148) extending substantially parallel to the longitudinal axis of the shaft (46, 146); and a fenestrated coupler (16, 116, 200) attached to the first and second rods (12, 112, 14, 114) in an operative configuration, the fenestrated coupler (16, 116, 200) having a superior face (50, 150), an inferior face (52, 152), an anterior face (54, 154), a posterior face (56, 156), a first lateral face (58, 158) and a second lateral face, at least one of the faces comprising at least one opening (60, 160) in fluid communication with at least a portion of the plurality of channels (26, 126, 48, 148) of the first and second rods (12, 112, 14, 114); characterised in that the superior face (50, 150) of the coupler (16, 116, 200) comprises a removable endplate (90, 190) and the inferior face (52, 152) comprises a removable endplate (92, 192), each of the endplates (90, 92, 190, 192) comprising a plurality of throughholes (95, 195).