An aerosol generation device, comprising: a cartridge storing an aerosol source; a cartridge accommodation portion formed in a bottomed cylindrical shape and configured to accommodate the cartridge; a suction port portion screwed to the cartridge accommodation portion and in which a suction port for suctioning the aerosol atomized by the aerosol source is formed; and characterized by a position-alignment mechanism configured to perform position alignment of the cartridge with respect to the cartridge accommodation portion the position-alignment mechanism comprises: an engagement convex portion disposed in either of the cartridge or the cartridge accommodation portion, the engagement convex portion protruding toward the other of the cartridge or the cartridge accommodation portion in an axial direction in which a central axis of the cartridge accommodation portion extends; and an engagement concave groove portion disposed in the other of the cartridge or the cartridge accommodation portion and to which the engagement convex portion is insertable in the axial direction, and wherein the engagement convex portion and the engagement concave groove portion are formed in the same radius with the central axis as a center, such that the position alignment is performed by interlocking the engagement convex portion with the engagement concave groove portion during the screwing of the suction port portion with respect to the cartridge accommodation portion. a cartridge storing an aerosol source; a cartridge accommodation portion formed in a bottomed cylindrical shape and configured to accommodate the cartridge; a suction port portion screwed to the cartridge accommodation portion and in which a suction port for suctioning the aerosol atomized by the aerosol source is formed; and characterized by a position-alignment mechanism configured to perform position alignment of the cartridge with respect to the cartridge accommodation portion the position-alignment mechanism comprises: an engagement convex portion disposed in either of the cartridge or the cartridge accommodation portion, the engagement convex portion protruding toward the other of the cartridge or the cartridge accommodation portion in an axial direction in which a central axis of the cartridge accommodation portion extends; and an engagement concave groove portion disposed in the other of the cartridge or the cartridge accommodation portion and to which the engagement convex portion is insertable in the axial direction, and an engagement convex portion disposed in either of the cartridge or the cartridge accommodation portion, the engagement convex portion protruding toward the other of the cartridge or the cartridge accommodation portion in an axial direction in which a central axis of the cartridge accommodation portion extends; and an engagement concave groove portion disposed in the other of the cartridge or the cartridge accommodation portion and to which the engagement convex portion is insertable in the axial direction, and wherein the engagement convex portion and the engagement concave groove portion are formed in the same radius with the central axis as a center, such that the position alignment is performed by interlocking the engagement convex portion with the engagement concave groove portion during the screwing of the suction port portion with respect to the cartridge accommodation portion.