A drug containing device comprising: a barrel; a valve for permitting mixing of at least two components, said valve being disposed in said barrel and including a body configured for slideable liquid tight engagement with said barrel, said body having a proximal end, a distal end, and a channel extending therebetween, said channel having a proximal portion and a distal portion; and, a poppet sealingly and slidably disposed in said channel to selectively move between closed and open positions relative to said body, said poppet having a proximal end, a distal end, and a fluid channel, said fluid channel defined in said poppet and extending from an outlet opening located distally of said distal end of said body; wherein, a first portion of said poppet is in engagement with said barrel, wherein a second portion of said poppet is in engagement with said channel, wherein, with said poppet in said closed position relative to said body, said poppet defining a liquid tight seal in said channel such that liquid flow through said channel is prevented, and, wherein, with said poppet in said open position relative to said body, said fluid channel being in communication with said proximal portion of said channel so as to define a liquid flow path from said proximal portion of said channel to said outlet opening, wherein said poppet includes a stem and a head, said stem defining the proximal end of said poppet and said head defining the distal end of said poppet, the device being characterized in that, under application of a sufficient amount of pressure to a wet component disposed within the barrel proximally of the valve, the applied pressure being transmitted to the body, the body moves distally relative to the stem of the poppet with the poppet remaining generally in a fixed position, from the closed position to the open position, with the frictional resistance against movement generated at the interface between the head of said poppet and said barrel being greater than the frictional resistance against movement generated at the interface between the stem of said poppet and said channel. a barrel; a valve for permitting mixing of at least two components, said valve being disposed in said barrel and including a body configured for slideable liquid tight engagement with said barrel, said body having a proximal end, a distal end, and a channel extending therebetween, said channel having a proximal portion and a distal portion; and, a poppet sealingly and slidably disposed in said channel to selectively move between closed and open positions relative to said body, said poppet having a proximal end, a distal end, and a fluid channel, said fluid channel defined in said poppet and extending from an outlet opening located distally of said distal end of said body; a body configured for slideable liquid tight engagement with said barrel, said body having a proximal end, a distal end, and a channel extending therebetween, said channel having a proximal portion and a distal portion; and, a poppet sealingly and slidably disposed in said channel to selectively move between closed and open positions relative to said body, said poppet having a proximal end, a distal end, and a fluid channel, said fluid channel defined in said poppet and extending from an outlet opening located distally of said distal end of said body; wherein, a first portion of said poppet is in engagement with said barrel, wherein a second portion of said poppet is in engagement with said channel, wherein, with said poppet in said closed position relative to said body, said poppet defining a liquid tight seal in said channel such that liquid flow through said channel is prevented, and, wherein, with said poppet in said open position relative to said body, said fluid channel being in communication with said proximal portion of said channel so as to define a liquid flow path from said proximal portion of said channel to said outlet opening, wherein said poppet includes a stem and a head, said stem defining the proximal end of said poppet and said head defining the distal end of said poppet, the device being characterized in that, under application of a sufficient amount of pressure to a wet component disposed within the barrel proximally of the valve, the applied pressure being transmitted to the body, the body moves distally relative to the stem of the poppet with the poppet remaining generally in a fixed position, from the closed position to the open position, with the frictional resistance against movement generated at the interface between the head of said poppet and said barrel being greater than the frictional resistance against movement generated at the interface between the stem of said poppet and said channel.