A display screen, comprising a display frame, a display module detachably connected to the display frame, and a locking mechanism mounted on a back of the display module for locking the display module on the display frame; wherein the display frame has at least two frame bars arranged in a row and at intervals, and any two adjacent frame bars are provided with at least two engaged grooves spaced opposite to each other; the locking mechanism comprises two telescopic rods and a drive assembly for driving the two telescopic rods to be inserted into or pulled out from the engaged grooves arranged on the two frame bars, respectively; the drive assembly is installed on the back of the display module and connected to the two telescopic rods.; wherein, the drive assembly is a knob assembly arranged on the back of the display module, and one end of each of the two telescopic rods is hinged with a side of the knob assembly; wherein, the knob assembly comprises a knob and a rotating member with one end connected to the knob, and the one end of each of the two telescopic rods is hinged with a side of the rotating member; wherein, the rotating member comprises a plate body, a first bulge disposed on a side of the plate body, and a second bulge arranged on the other side of the plate body; the first bulge is connected to the knob; a limiting hole is arranged on the back of the display module, and the second bulge is mounted in the limiting hole and capable of rotating in the limiting hole; characterized in that the one end of each of the two telescopic rods is hinged with a side of the plate body; the plate body is respectively provided with a first through hole on both sides, the first through holes are oppositely arranged in an extension direction of the first bulge, and one end of each of the two telescopic rods is provided with a second through hole; the locking mechanism further comprises two pins, and the telescopic rods are hinged with the plate body by means of the pins penetrating the first through hole and the second through hole: and the display module is provided with two arc-shaped holes on a side of the limiting hole at an interval along a circumferential direction, and one end of each pin away from the knob is arranged in the arc-shaped hole and capable of sliding in the arc-shaped hole; and/or, the display module comprises a module bracket and a lamp panel mounted on the module bracket; the locking mechanism is arranged on a back of the module bracket, and the module bracket is provided with the limiting hole; the second bulge is provided with an inner hexagonal hole, and the lamp panel is provided with a disassembly hole in alignment with the limiting hole penetrating the lamp panel. wherein, the drive assembly is a knob assembly arranged on the back of the display module, and one end of each of the two telescopic rods is hinged with a side of the knob assembly; wherein, the knob assembly comprises a knob and a rotating member with one end connected to the knob, and the one end of each of the two telescopic rods is hinged with a side of the rotating member; wherein, the rotating member comprises a plate body, a first bulge disposed on a side of the plate body, and a second bulge arranged on the other side of the plate body; the first bulge is connected to the knob; a limiting hole is arranged on the back of the display module, and the second bulge is mounted in the limiting hole and capable of rotating in the limiting hole; characterized in that the one end of each of the two telescopic rods is hinged with a side of the plate body; the plate body is respectively provided with a first through hole on both sides, the first through holes are oppositely arranged in an extension direction of the first bulge, and one end of each of the two telescopic rods is provided with a second through hole; the locking mechanism further comprises two pins, and the telescopic rods are hinged with the plate body by means of the pins penetrating the first through hole and the second through hole: and the display module is provided with two arc-shaped holes on a side of the limiting hole at an interval along a circumferential direction, and one end of each pin away from the knob is arranged in the arc-shaped hole and capable of sliding in the arc-shaped hole; and/or, the display module comprises a module bracket and a lamp panel mounted on the module bracket; the locking mechanism is arranged on a back of the module bracket, and the module bracket is provided with the limiting hole; the second bulge is provided with an inner hexagonal hole, and the lamp panel is provided with a disassembly hole in alignment with the limiting hole penetrating the lamp panel. the display module is provided with two arc-shaped holes on a side of the limiting hole at an interval along a circumferential direction, and one end of each pin away from the knob is arranged in the arc-shaped hole and capable of sliding in the arc-shaped hole; and/or, the display module comprises a module bracket and a lamp panel mounted on the module bracket; the locking mechanism is arranged on a back of the module bracket, and the module bracket is provided with the limiting hole; the second bulge is provided with an inner hexagonal hole, and the lamp panel is provided with a disassembly hole in alignment with the limiting hole penetrating the lamp panel.