A compound of formula I where: R 1 is phenyl or pyridinyl and is substituted with 0-3 substituents selected from the group consisting of halo, alkyl, cycloalkyl, haloalkyl, hydroxyalkyl, alkoxyalkyl, alkoxy, cycloalkoxy, hydroxyalkyloxy, and alkoxyalkyloxy, provided that the phenyl or pyridinyl is also substituted with 1 CON(R 9)(R 10) substituent; R 2 is hydrogen, halo, alkyl, or alkoxy; R 3 is cyano, alkoxycarbonyl, (cycloalkyl)oxycarbonyl, (alkylsulfonyl)aminocarbonyl, CON(R 13)(R 14), (R 13)(R 14)NCONH, thiazolyl, tetrazolyl, triazolyl, or imidazolyl wherein the thiazolyl, tetrazolyl, triazolyl, or imidazolyl is substituted with 0-3 halo or alkyl substituents; R 4 is phenyl that is independently substituted with 0-2 halo, alkyl, or alkoxy or is para substituted with X-Ar 1; R 5 and R 6 are independently hydrogen, nitro, halo, alkyl, alkoxy, N(R 7)(R 8), or alkylsulfonyl; R 7 and R 8 are independently hydrogen, alkyl, cyanoalkyl, haloalkyl, (cycloalkyl)alkyl, cycloalkyl, hydroxyalkyl, alkoxyalkyl, alkylcarbonyl, alkoxycarbonyl, haloalkoxycarbonyl, alkylsulfonyl, alkylsulfonylalkyl, SO 2 N(R 15)(R 16), or benzyl where said benzyl is substituted with 0-3 substituents selected from halo, alkyl, haloalkyl, alkoxy, haloalkoxy, carboxy, and alkoxycarbonyl; or N(R 7)(R 8) taken together is azetidinyl, pyrrolidinyl, piperidinyl, or piperazinyl, and is substituted with 0-2 substituents selected from alkyl, hydroxyalkyl, or hydroxy; R 9 is R 10 is hydrogen; R 11 and R 12 taken together with the carbon to which they are attached is azetidinyl substituted with 0-3 alkyl substituents; R 13 is hydrogen or alkyl; R 14 is hydrogen or alkyl; R 15 is hydrogen or alkyl; R 16 is hydrogen or alkyl; X is -O- or -NH-; Ar 1 is phenyl or para-halophenyl; and Ar 2 is phenyl, pyridinyl, pyrazinyl, pyrimidinyl, pyrazolyl, isoxazolyl, imidazolyl, oxazolyl, thiazolyl, oxadiazolyl, oxadiathiazolyl, triazolyl, or tetrazolyl, and is substituted with 0-3 substituents selected from halo, alkyl, or dialkylamino; or a pharmaceutically acceptable salt thereof. R 1 is phenyl or pyridinyl and is substituted with 0-3 substituents selected from the group consisting of halo, alkyl, cycloalkyl, haloalkyl, hydroxyalkyl, alkoxyalkyl, alkoxy, cycloalkoxy, hydroxyalkyloxy, and alkoxyalkyloxy, provided that the phenyl or pyridinyl is also substituted with 1 CON(R 9)(R 10) substituent; R 2 is hydrogen, halo, alkyl, or alkoxy; R 3 is cyano, alkoxycarbonyl, (cycloalkyl)oxycarbonyl, (alkylsulfonyl)aminocarbonyl, CON(R 13)(R 14), (R 13)(R 14)NCONH, thiazolyl, tetrazolyl, triazolyl, or imidazolyl wherein the thiazolyl, tetrazolyl, triazolyl, or imidazolyl is substituted with 0-3 halo or alkyl substituents; R 4 is phenyl that is independently substituted with 0-2 halo, alkyl, or alkoxy or is para substituted with X-Ar 1; R 5 and R 6 are independently hydrogen, nitro, halo, alkyl, alkoxy, N(R 7)(R 8), or alkylsulfonyl; R 7 and R 8 are independently hydrogen, alkyl, cyanoalkyl, haloalkyl, (cycloalkyl)alkyl, cycloalkyl, hydroxyalkyl, alkoxyalkyl, alkylcarbonyl, alkoxycarbonyl, haloalkoxycarbonyl, alkylsulfonyl, alkylsulfonylalkyl, SO 2 N(R 15)(R 16), or benzyl where said benzyl is substituted with 0-3 substituents selected from halo, alkyl, haloalkyl, alkoxy, haloalkoxy, carboxy, and alkoxycarbonyl; or N(R 7)(R 8) taken together is azetidinyl, pyrrolidinyl, piperidinyl, or piperazinyl, and is substituted with 0-2 substituents selected from alkyl, hydroxyalkyl, or hydroxy; R 9 is R 10 is hydrogen; R 11 and R 12 taken together with the carbon to which they are attached is azetidinyl substituted with 0-3 alkyl substituents; R 13 is hydrogen or alkyl; R 14 is hydrogen or alkyl; R 15 is hydrogen or alkyl; R 16 is hydrogen or alkyl; X is -O- or -NH-; Ar 1 is phenyl or para-halophenyl; and Ar 2 is phenyl, pyridinyl, pyrazinyl, pyrimidinyl, pyrazolyl, isoxazolyl, imidazolyl, oxazolyl, thiazolyl, oxadiazolyl, oxadiathiazolyl, triazolyl, or tetrazolyl, and is substituted with 0-3 substituents selected from halo, alkyl, or dialkylamino; or a pharmaceutically acceptable salt thereof.