An ocular implant system for implantation of an ocular implant into an eye, comprising: an ocular implant having: an internal lumen having an inner diameter within the ocular implant for forming a flow pathway; at least one inflow port communicating with the internal lumen; and at least one outflow port communicating with the internal lumen; wherein, when the ocular implant is positioned in a deployed location in the eye, the at least one inflow port is in communication with the anterior chamber and the at least one outflow port is in communication with the suprachoroidal space such that the implant provides a flow pathway for draining aqueous humor from the anterior chamber toward the suprachoroidal space; and the ocular implant system further comprising a delivery instrument comprising: a proximal handle; and a delivery component including: an elongated applier element formed of an elongated body that releasably couples to the ocular implant by being longitudinally inserted through the internal lumen, wherein the elongated body has an outer diameter sufficiently smaller than the inner diameter of the internal lumen creating a gap for a retention layer; the retention layer; and a sheath positioned axially over the applier, wherein the delivery instrument is adapted for deployment of the ocular implant into the deployed location in the eye through a corneal incision, through the anterior chamber through an internal space between the ciliary body and the sclera formed upon detachment of at least a portion of the ciliary body from the sclera, and wherein the delivery instrument is adapted for detachment of the ocular implant from the elongated applier element and into the deployed location. an internal lumen having an inner diameter within the ocular implant for forming a flow pathway; at least one inflow port communicating with the internal lumen; and at least one outflow port communicating with the internal lumen; wherein, when the ocular implant is positioned in a deployed location in the eye, the at least one inflow port is in communication with the anterior chamber and the at least one outflow port is in communication with the suprachoroidal space such that the implant provides a flow pathway for draining aqueous humor from the anterior chamber toward the suprachoroidal space; and the ocular implant system further comprising a delivery instrument comprising: a proximal handle; and a delivery component including: an elongated applier element formed of an elongated body that releasably couples to the ocular implant by being longitudinally inserted through the internal lumen, wherein the elongated body has an outer diameter sufficiently smaller than the inner diameter of the internal lumen creating a gap for a retention layer; the retention layer; and a sheath positioned axially over the applier, wherein the delivery instrument is adapted for deployment of the ocular implant into the deployed location in the eye through a corneal incision, through the anterior chamber through an internal space between the ciliary body and the sclera formed upon detachment of at least a portion of the ciliary body from the sclera, and wherein the delivery instrument is adapted for detachment of the ocular implant from the elongated applier element and into the deployed location. a proximal handle; and a delivery component including: an elongated applier element formed of an elongated body that releasably couples to the ocular implant by being longitudinally inserted through the internal lumen, wherein the elongated body has an outer diameter sufficiently smaller than the inner diameter of the internal lumen creating a gap for a retention layer; the retention layer; and a sheath positioned axially over the applier, an elongated applier element formed of an elongated body that releasably couples to the ocular implant by being longitudinally inserted through the internal lumen, wherein the elongated body has an outer diameter sufficiently smaller than the inner diameter of the internal lumen creating a gap for a retention layer; the retention layer; and a sheath positioned axially over the applier, wherein the delivery instrument is adapted for deployment of the ocular implant into the deployed location in the eye through a corneal incision, through the anterior chamber through an internal space between the ciliary body and the sclera formed upon detachment of at least a portion of the ciliary body from the sclera, and wherein the delivery instrument is adapted for detachment of the ocular implant from the elongated applier element and into the deployed location.