mhurhangee/ep-ind-claims huggingface dataset:
A method of reprogramming a mammalian somatic cell, comprising contacting the mammalian somatic cell with: a Wnt-conditioned medium comprising a concentration of 100 ng/mL to 1000 ng/mL secreted Wnt3a protein; an unconditioned medium comprising at least 5% of the conditioned medium by volume; or a Wnt pathway activator selected from the group consisting of: an exogenous, soluble, biologically active Wnt protein that binds to a Wnt receptor and activates the Wnt pathway, and a small molecule GSK-3 antagonist that activates the Wnt pathway selected from the group consisting of: 6-Bromoindirubin-3'-oxime; N-(4-Methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea (AR-AO 14418); 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione (SB 216763); 4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione (TDZD-8); CHIR-911, and CHIR-837; and reprogramming factors Oct4, Klf4, and Sox2, thereby reprogramming the cell to a pluripotent state. a Wnt-conditioned medium comprising a concentration of 100 ng/mL to 1000 ng/mL secreted Wnt3a protein; an unconditioned medium comprising at least 5% of the conditioned medium by volume; or a Wnt pathway activator selected from the group consisting of: an exogenous, soluble, biologically active Wnt protein that binds to a Wnt receptor and activates the Wnt pathway, and a small molecule GSK-3 antagonist that activates the Wnt pathway selected from the group consisting of: 6-Bromoindirubin-3'-oxime; N-(4-Methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea (AR-AO 14418); 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione (SB 216763); 4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione (TDZD-8); CHIR-911, and CHIR-837; and reprogramming factors Oct4, Klf4, and Sox2, thereby reprogramming the cell to a pluripotent state.
An image and text typesetting computer-implemented method, comprising: determining an importance measurement value of each pixel in an image; obtaining at least one text box area formed by at least one text box overlapped on the image, wherein the text box area is an area range of a background image obtained after the image is captured by using a coordinate axis of the text box as a boundary, and a background image corresponding to each of the at least one text box area comprises at least one pixel; obtaining, based on an importance measurement value of the pixels in the background image corresponding to each text box area, an importance measurement value of the background image corresponding to each text box area; obtaining an importance measurement value gravity center or an importance measurement value mass center of the image based on the importance measurement values of the pixels in the image; determining, based on a preset principle and a location relationship between the importance measurement value gravity center and a central area of the image or a location relationship between the importance measurement value mass center and a central area of the image, information about a balance degree of each text box area relative to the image; and selecting, from the at least one text box area based on the importance measurement value of the background image corresponding to each text box area and the information about the balance degree of each text box area, one text box area to typeset a word. determining an importance measurement value of each pixel in an image; obtaining at least one text box area formed by at least one text box overlapped on the image, wherein the text box area is an area range of a background image obtained after the image is captured by using a coordinate axis of the text box as a boundary, and a background image corresponding to each of the at least one text box area comprises at least one pixel; obtaining, based on an importance measurement value of the pixels in the background image corresponding to each text box area, an importance measurement value of the background image corresponding to each text box area; obtaining an importance measurement value gravity center or an importance measurement value mass center of the image based on the importance measurement values of the pixels in the image; determining, based on a preset principle and a location relationship between the importance measurement value gravity center and a central area of the image or a location relationship between the importance measurement value mass center and a central area of the image, information about a balance degree of each text box area relative to the image; and selecting, from the at least one text box area based on the importance measurement value of the background image corresponding to each text box area and the information about the balance degree of each text box area, one text box area to typeset a word.
Method for developing a predictive control setpoint that can be implanted in a trajectory control unit of a motor vehicle, the method comprising, for at least one given speed of movement of the motor vehicle on a traffic lane, steps of: - determining a plurality of regulation data (K S), each regulation datum (K S) making it possible, from at least one input datum, to generate the command setpoint which satisfies a robustness parameter, and each regulation datum (K S) being associated with a particular configuration of use of said motor vehicle, - identifying at least one regulation datum (K S) out of the plurality of determined regulation data (K S), as a function of a result of a simulation of the trajectory of the motor vehicle on the traffic lane, and - using said at least one identified regulation datum to control the trajectory of said motor vehicle. - determining a plurality of regulation data (K S), each regulation datum (K S) making it possible, from at least one input datum, to generate the command setpoint which satisfies a robustness parameter, and each regulation datum (K S) being associated with a particular configuration of use of said motor vehicle, - identifying at least one regulation datum (K S) out of the plurality of determined regulation data (K S), as a function of a result of a simulation of the trajectory of the motor vehicle on the traffic lane, and - using said at least one identified regulation datum to control the trajectory of said motor vehicle.
Interlock for an access protection device for a lockable area of a machine installation comprising an electromagnet, which by means of an actuation system can be controlled in at least two states of different energy requirements, wherein the interlock is designed for connection to a fieldbus, and a switching controller of the interlock being supplied from the fieldbus is used as voltage supply and is connected in series to a current source, which together with an energy store unit forms a Kirchhoff's node, wherein the Kirchhoff's node is connected to the actuation system for the electromagnet, and the energy store unit that charges during the state of low energy requirement provides energy for the higher energy requirement and wherein the electromagnet is current-controlled by means of the actuation system and the current source unit is a constant current source unit.
A sleep awaking system comprising: a physical sign parameter collecting module configured to collect a physical sign parameter of a human body; a time determining module configured to determine whether the present time is a REM determining time; a REM determining module configured to obtain the physical sign parameter and determine whether the human body is in a REM stage according to the physical sign parameter in a REM determining period when the time determining module determines that the present time is the REM determining time; an awaking module configured to awake the human body after a pre-awaking period, wherein if the REM determining module determines that the human body is in the REM stage, the awaking module is configured to awake the human body after the pre-awaking period by emitting white light changing gradually from weak to strong within the awaking buffering period after the pre-awaking period until the human body is awaked or the awaking buffering period is over, and stopping emitting the white light changing gradually from weak to strong, and if the REM determining module determines that the human body is not in the REM stage, the awaking module is configured to cause the human body to enter the REM stage by emitting a blue light which is changed gradually from weak to strong within the pre-awaking period and awake the human body after the pre-awaking period, wherein the REM determining period and the pre-awaking period pass in turn from the REM determining time to the awaking time. a physical sign parameter collecting module configured to collect a physical sign parameter of a human body; a time determining module configured to determine whether the present time is a REM determining time; a REM determining module configured to obtain the physical sign parameter and determine whether the human body is in a REM stage according to the physical sign parameter in a REM determining period when the time determining module determines that the present time is the REM determining time; an awaking module configured to awake the human body after a pre-awaking period, wherein if the REM determining module determines that the human body is in the REM stage, the awaking module is configured to awake the human body after the pre-awaking period by emitting white light changing gradually from weak to strong within the awaking buffering period after the pre-awaking period until the human body is awaked or the awaking buffering period is over, and stopping emitting the white light changing gradually from weak to strong, and if the REM determining module determines that the human body is not in the REM stage, the awaking module is configured to cause the human body to enter the REM stage by emitting a blue light which is changed gradually from weak to strong within the pre-awaking period and awake the human body after the pre-awaking period, wherein the REM determining period and the pre-awaking period pass in turn from the REM determining time to the awaking time.
Linear compressor for a household appliance, with a piston movable in the longitudinal direction of a cylinder between an upper and lower dead-centre position, whose piston outer surface can be stored in the radial direction of the cylinder in a contactless manner opposite a corresponding cylinder inner surface to form a gas pressure bearing, characterised in that the piston outer surface and the cylinder inner surface have a martensitic microstructure at least in an area (40, 42) predefined in each case.
A coacervate formed by mixing a catechol derivative of a mussel adhesive protein and a catechol-substituted hyaluronic acid, wherein a substitution degree of the catechol of the hyaluronic acid is 10 to 52%.
A screen segment of a screening device for separating or classifying feed material, especially mineral crushed material such as oil sand, into at least two grain fractions, wherein the screen segment comprises a base plate essentially in the form of a screen having a multitude of screen passages, wherein at least one antiwear unit has been mounted on the base plate, wherein the antiwear unit has been formed from a metal matrix composite material having an antiwear insert made of a hard metal and/or of ceramic, characterized in that the metal matrix composite material comprises a metal matrix material and wherein the antiwear insert is cast at least partially into the metal matrix material of the antiwear unit. the antiwear unit has been formed from a metal matrix composite material having an antiwear insert made of a hard metal and/or of ceramic, characterized in that the metal matrix composite material comprises a metal matrix material and wherein the antiwear insert is cast at least partially into the metal matrix material of the antiwear unit.
A medical implant and delivery tool package comprising: a wet compartment containing a fluid; a dry compartment; an implant at least partially stored inside the wet compartment; a delivery tool connected to the implant at least partially stored inside the dry compartment; a seal between the wet compartment and dry compartment; an additional seal in the handle. a wet compartment containing a fluid; a dry compartment; an implant at least partially stored inside the wet compartment; a delivery tool connected to the implant at least partially stored inside the dry compartment; a seal between the wet compartment and dry compartment; an additional seal in the handle.
A reciprocating engine, comprising: a cylinder liner having an inner wall and extending around a cavity, wherein the inner wall comprises a first axial end, a second axial end, a piston travel portion, and a top portion, wherein the top portion is nearer to the first axial end of the cylinder liner than to the second axial end of the cylinder liner, the top portion comprises a first surface finish, the first surface finish comprises a first roughness (Ra 1) greater than approximately 2 μm and a total waviness (W t) less than approximately 0.1 mm, and wherein the first roughness (Ra 1) and the total waviness (Wt) are based on a characteristic length of approximately 0.8 mm; and a piston disposed within the cavity and configured to move in a reciprocating manner within the cylinder liner, wherein the piston comprises a top land configured to be radially opposite the top portion of the inner wall of the cylinder liner when the piston is at a top dead center position, a second surface finish of the top land of the piston comprises a second roughness average (Ra 2) less than approximately 2 μm, wherein the second roughness (Ra 2) is less than the first roughness (Ra 1), and the second roughness (Ra 2) is based on the characteristic length of approximately 0.8 mm. a cylinder liner having an inner wall and extending around a cavity, wherein the inner wall comprises a first axial end, a second axial end, a piston travel portion, and a top portion, wherein the top portion is nearer to the first axial end of the cylinder liner than to the second axial end of the cylinder liner, the top portion comprises a first surface finish, the first surface finish comprises a first roughness (Ra 1) greater than approximately 2 μm and a total waviness (W t) less than approximately 0.1 mm, and wherein the first roughness (Ra 1) and the total waviness (Wt) are based on a characteristic length of approximately 0.8 mm; and a piston disposed within the cavity and configured to move in a reciprocating manner within the cylinder liner, wherein the piston comprises a top land configured to be radially opposite the top portion of the inner wall of the cylinder liner when the piston is at a top dead center position, a second surface finish of the top land of the piston comprises a second roughness average (Ra 2) less than approximately 2 μm, wherein the second roughness (Ra 2) is less than the first roughness (Ra 1), and the second roughness (Ra 2) is based on the characteristic length of approximately 0.8 mm.
An optical beam delivery device configured to facilitate coordination of different states of applied perturbation with changes of optical power of an optical beam generated by a laser source, the optical beam delivery device comprising: a first length of fiber (104; 204; 1100; 1300; 1400; 1406; 1500; 1500; 1600; 2912) having a first refractive index profile (212; 1102; 1202; 1302; 1402; 1412; 1504; 1602), the first RIP enabling, in response to an applied perturbation, modification of the optical beam to form an adjusted optical beam, the adjusted optical beam defining, at an output end of the first length of fiber, different intensity distributions based on different states of the applied perturbation; and a second length of fiber (108; 208; 1700; 1800; 1900; 2000; 2100; 2920) having an input end coupled to the output end of the first length of fiber, the second length of fiber formed with multiple confinement regions (216, 218, 220; 1704, 1706, 1708; 1808, 1810, 1812; 1904, 1906, 1908, 1910; 2004, 2006, 2008; 2104, 2106, 2108) defining a second RIP (1702; 1802; 1902; 2002; 2102) that is different from the first RIP, the multiple confinement regions arranged to confine at least a portion of the adjusted optical beam, the confined portion (2940 A, 2940 B, 2940 C, 2940 D) corresponding to an intensity distribution of the different intensity distributions established by a controllable state of the different states of the applied perturbation such that the confined portion is adjustable to control, at an output end of the second length of fiber, optical power density provided by the confined portion of the adjusted optical beam. a first length of fiber (104; 204; 1100; 1300; 1400; 1406; 1500; 1500; 1600; 2912) having a first refractive index profile (212; 1102; 1202; 1302; 1402; 1412; 1504; 1602), the first RIP enabling, in response to an applied perturbation, modification of the optical beam to form an adjusted optical beam, the adjusted optical beam defining, at an output end of the first length of fiber, different intensity distributions based on different states of the applied perturbation; and a second length of fiber (108; 208; 1700; 1800; 1900; 2000; 2100; 2920) having an input end coupled to the output end of the first length of fiber, the second length of fiber formed with multiple confinement regions (216, 218, 220; 1704, 1706, 1708; 1808, 1810, 1812; 1904, 1906, 1908, 1910; 2004, 2006, 2008; 2104, 2106, 2108) defining a second RIP (1702; 1802; 1902; 2002; 2102) that is different from the first RIP, the multiple confinement regions arranged to confine at least a portion of the adjusted optical beam, the confined portion (2940 A, 2940 B, 2940 C, 2940 D) corresponding to an intensity distribution of the different intensity distributions established by a controllable state of the different states of the applied perturbation such that the confined portion is adjustable to control, at an output end of the second length of fiber, optical power density provided by the confined portion of the adjusted optical beam.
Coating agent, comprising (a) at least one thermoplastic polymer in a proportion of at least 30% by weight of the solid content of the coating agent; (b) at least one UV hardenable reactive thinner in a proportion of at least 30% by weight of the solid content of the coating agent; (c) at least one photo-initiator; and (d) at least one organic solvent, wherein the proportion of ethylenically unsaturated groups amounts to at least 3 mol per kg of the solid content of the coating agent, wherein the at least one reactive thinner comprises at least three polymerisable (meth)acrylate functions in the molecule and wherein the ester-oxygen atoms of the (meth)acrylate functions in the molecule of the reactive thinner are separated from one another by a chain of at least six atoms. (a) at least one thermoplastic polymer in a proportion of at least 30% by weight of the solid content of the coating agent; (b) at least one UV hardenable reactive thinner in a proportion of at least 30% by weight of the solid content of the coating agent; (c) at least one photo-initiator; and (d) at least one organic solvent,
Winding device for winding a rope onto a rope drum, which is rotatable about an axis of rotation and comprises a rope guide for feeding the rope to the rope drum, wherein the rope guide has a pivoting arm having a longitudinal axis and has a deflection element, wherein the pivoting arm is pivotable about a pivot axis, wherein the deflection element is arranged on the pivoting arm, wherein the winding device is designed such that the rope, when being wound onto the rope drum, passes the pivoting arm before the deflection element, characterized in that the rope guide comprises a delimitation element, and in that the delimitation element is arranged such that a pivoting movement of the pivoting arm about the pivot axis is limited to a critical angular range (Δ), in that the deflection element is tiltable about a tilting axis, and in that the tilting axis extends along the longitudinal axis of the pivoting arm.
A method of printing spots on a substrate with high spot placement accuracy, the method comprising: Setting up a plurality of components of a printing system having a process direction, where the plurality of components includes a camera and one or more print heads with one or more ejectors on each print head; ejecting at least one drop from all of the ejectors of at least one print head to form printed spots on a substrate; using the camera to measure the positions of the printed spots from the print head; and storing the measured spot positions in a common coordinate system as initial virtual positions describing at least one virtual print head, characterized by calculating a printing sequence to be used to make a desired image based on the virtual print head descriptions. printing an image with the calculated printing sequence utilizing the virtual print head descriptions. Setting up a plurality of components of a printing system having a process direction, where the plurality of components includes a camera and one or more print heads with one or more ejectors on each print head; ejecting at least one drop from all of the ejectors of at least one print head to form printed spots on a substrate; using the camera to measure the positions of the printed spots from the print head; and storing the measured spot positions in a common coordinate system as initial virtual positions describing at least one virtual print head, calculating a printing sequence to be used to make a desired image based on the virtual print head descriptions. printing an image with the calculated printing sequence utilizing the virtual print head descriptions.