A device configured to detect an improvement in a seizure condition of a patient, the device comprising: at least one EEG sensor configured to generate EEG data; at least one heart rate sensor configured to generate heart rate data; and a therapy analysis device configured to receive the EEG data and the heart rate data, wherein the therapy analysis device is configured to evaluate an effect of a therapy, the evaluation comprising: identifying an EEG synchronization of a first seizure of the patient; identifying a first amount of heart rate increase of the seizure condition of the patient; applying a therapy configured to improve the seizure condition of the patient; identifying an EEG synchronization of a second seizure of the patient subsequent to application of the therapy, wherein an improvement of the seizure condition of the patient is demonstrated by a reduced EEG synchronization of the patient such that the second EEG synchronization is less than the first EEG synchronization; identifying a second amount of heart rate increase of the seizure condition of the patient subsequent to application of the therapy, wherein an improvement of the seizure condition of the patient is demonstrated by a reduced increase in heart rate of the patient wherein the second amount of heart rate increase is less than the first amount of heart rate increase; and modifying parameters of the therapy based on at least one of the second EEG synchronization or a comparison of the first and second EEG synchronization. at least one EEG sensor configured to generate EEG data; at least one heart rate sensor configured to generate heart rate data; and a therapy analysis device configured to receive the EEG data and the heart rate data, wherein the therapy analysis device is configured to evaluate an effect of a therapy, the evaluation comprising: identifying an EEG synchronization of a first seizure of the patient; identifying a first amount of heart rate increase of the seizure condition of the patient; applying a therapy configured to improve the seizure condition of the patient; identifying an EEG synchronization of a second seizure of the patient subsequent to application of the therapy, wherein an improvement of the seizure condition of the patient is demonstrated by a reduced EEG synchronization of the patient such that the second EEG synchronization is less than the first EEG synchronization; identifying a second amount of heart rate increase of the seizure condition of the patient subsequent to application of the therapy, wherein an improvement of the seizure condition of the patient is demonstrated by a reduced increase in heart rate of the patient wherein the second amount of heart rate increase is less than the first amount of heart rate increase; and modifying parameters of the therapy based on at least one of the second EEG synchronization or a comparison of the first and second EEG synchronization. identifying an EEG synchronization of a first seizure of the patient; identifying a first amount of heart rate increase of the seizure condition of the patient; applying a therapy configured to improve the seizure condition of the patient; identifying an EEG synchronization of a second seizure of the patient subsequent to application of the therapy, wherein an improvement of the seizure condition of the patient is demonstrated by a reduced EEG synchronization of the patient such that the second EEG synchronization is less than the first EEG synchronization; identifying a second amount of heart rate increase of the seizure condition of the patient subsequent to application of the therapy, wherein an improvement of the seizure condition of the patient is demonstrated by a reduced increase in heart rate of the patient wherein the second amount of heart rate increase is less than the first amount of heart rate increase; and modifying parameters of the therapy based on at least one of the second EEG synchronization or a comparison of the first and second EEG synchronization.