mhurhangee/ep-ind-claims huggingface dataset:
A cutter for an assay cartridge comprising a base member defining two or more wells (30, 32, 34, 36, 38) and a cap member arranged to carry a pipette (108, 110) positionable in at least two of said wells, characterised in that the cutter comprises: two shearing blades for shearing a foil seal covering one of the wells, the two shearing blades being linear and parallel to each other, and a third blade extending between the two shearing blades, spaced away from the ends of the shearing blades. two shearing blades for shearing a foil seal covering one of the wells, the two shearing blades being linear and parallel to each other, and a third blade extending between the two shearing blades, spaced away from the ends of the shearing blades.
A vat system, comprising: a vat that defines an enclosure having a top wall, a bottom wall, and side walls (14, 15), all of which extend longitudinally between a pair of end walls (18, 19), and a shaft arranged within the enclosure of the vat at a shaft height at which the shaft is provided with respect to the vat; characterized in that it further comprises a temporary shaft support system comprising: a holder for engaging and holding the shaft within the enclosure and a lift that is supported by and provided outside of the enclosure, the lift being connected to the holder for moving the holder in a generally vertical direction for temporarily supporting the shaft. a vat that defines an enclosure having a top wall, a bottom wall, and side walls (14, 15), all of which extend longitudinally between a pair of end walls (18, 19), and a shaft arranged within the enclosure of the vat at a shaft height at which the shaft is provided with respect to the vat; characterized in that it further comprises a temporary shaft support system comprising: a holder for engaging and holding the shaft within the enclosure and a lift that is supported by and provided outside of the enclosure, the lift being connected to the holder for moving the holder in a generally vertical direction for temporarily supporting the shaft. a holder for engaging and holding the shaft within the enclosure and a lift that is supported by and provided outside of the enclosure, the lift being connected to the holder for moving the holder in a generally vertical direction for temporarily supporting the shaft.
A preparation for use in a method of cell therapy for treating heart disease, comprising: a hydrogel containing a basic fibroblast growth factor; and pluripotent stem cells derived from heart tissue, wherein the preparation is formulated such that the basic fibroblast growth factor is administered in an amount of at least 1 to 100 μg with respect to the amount of the pluripotent stem cells of 1×10 6 cells; and wherein the preparation is formulated such that the pluripotent stem cells are administered in an amount of 1×10 6 cells or less per kg body weight of a patient.
A compound comprising a modified oligonucleotide consisting of 8 to 30 linked nucleosides and having a nucleobase sequence comprising a complementary region, wherein the complementary region comprises at least 8 contiguous nucleobases and is 100% complementary to an equal-length portion of a target region of a CLN3 transcript, wherein: (i) the nucleobase sequence of the oligonucleotide is at least 90% complementary to an equal-length region of the CLN3 transcript, as measured over the entire length of the oligonucleotide; and (ii) the modified oligonucleotide does not comprise more than 4 contiguous unmodified 2'deoxynucleosides; and wherein the compound is able to induce skipping of one or more exons of the CLN3 transcript, for use in the treatment of Batten Disease or for use in delaying or preventing the onset of Batten Disease. (i) the nucleobase sequence of the oligonucleotide is at least 90% complementary to an equal-length region of the CLN3 transcript, as measured over the entire length of the oligonucleotide; and (ii) the modified oligonucleotide does not comprise more than 4 contiguous unmodified 2'deoxynucleosides; and
A solid-state image sensor having a plurality of picture elements on a semiconductor substrate, each of the picture elements including: a photodiode for receiving light and generating photocharges; a floating diffusion region (13, 54) for collecting and holding electric charges generated by the photodiode; and a transfer transistor having a transfer gate between the photodiode and the floating diffusion region so as to transfer electric charges from the photodiode to the floating diffusion region, wherein, in a light-receiving surface of the photodiode, a region inside an arc drawn around the floating diffusion region (13, 54) and outside the transfer gate, and a region inside each of a plurality of extending portions radially extending outwards from the arc, are formed as regions whose conductivity type is same as a signal charge to be collected, characterized in that the floating diffusion region (13, 54) is located, when viewed in a planar view, at an edge of the light-receiving surface of the photodiode such that the floating diffusion region (13, 54) is not entirely surrounded by the light-receiving surface of the photodiode.
A gastro-resistant vehicle for the oral administration of at least one hydrophilic pharmacologically active substance that allows said active substance to pass from the intestinal lumen to the blood, optionally via the interstitial fluid, without any substantial denaturation or degradation of said substance, said gastro-resistant vehicle comprising a plurality of vectors comprising a hydrophilic matrix comprising as main constituent a poly(lactate-co-glycolate) or a mixture comprising a poly(lactate-co-glycolate) entrapping one or more hydrophilic active substances, the outer surface of said matrix being modified with one or more chemical species that give it an essentially lipophilic nature, said vectors being dispersed in a lipophilic medium itself contained in a gastric protection of solid nature.
A photography device, comprising: a wireless communication module configured to establish a wireless connection between the photography device and a wearable device; a photography assembly; and a control module configured to control the wireless communication module to transmit a preview image captured by the photography assembly to the wearable device, the preview image being transmitted in the form of thumbnails frame by frame by the wireless communication module to the wearable device to enable the wearable device to display to a user the received preview image; wherein the wireless communication module is further configured to receive a user control command transmitted by the wearable device, and the control module is further configured to control the photography assembly to perform an associated operation according to the user control command; wherein the user-control command comprises a photographing command; and the photography device being characterized in that: in order to perform the associated operation, the control module is further configured to first control the photography assembly to prompt another user to manually take a photograph so as to acquire a still image within a preset time, and to control the photography assembly to photograph automatically so as to obtain the still image when a manual photographing action is not received within the preset time. a wireless communication module configured to establish a wireless connection between the photography device and a wearable device; a photography assembly; and a control module configured to control the wireless communication module to transmit a preview image captured by the photography assembly to the wearable device, the preview image being transmitted in the form of thumbnails frame by frame by the wireless communication module to the wearable device to enable the wearable device to display to a user the received preview image; wherein the wireless communication module is further configured to receive a user control command transmitted by the wearable device, and the control module is further configured to control the photography assembly to perform an associated operation according to the user control command; wherein the user-control command comprises a photographing command; and the photography device being characterized in that: in order to perform the associated operation, the control module is further configured to first control the photography assembly to prompt another user to manually take a photograph so as to acquire a still image within a preset time, and to control the photography assembly to photograph automatically so as to obtain the still image when a manual photographing action is not received within the preset time.
A switch including one or more hybrid ports (156, 158), a local flow table containing flow definitions to indicate how a software defined data flow is processed in a software-defined network, and a local forwarding table for forwarding a regular data flow, the switch being configured to: logically partition a hybrid port into a first partition for frames belonging to the software-defined data flow and a second partition for frames belonging to the regular data flow; determine a frame received via said hybrid port as belonging to the software-defined flow or the regular data flow by checking one or more of: a virtual local area network (VLAN) tag or identifier; a type of a frame; and a flag in a header of a received frame; and if it is determined that the received frame belongs to the software-defined flow: control the frame based on the flow definition; or if it is determined that the received frame does not belong to the software-defined flow: perform a lookup on the frame in the local forwarding table to identify an output port; characterised in that the switch further comprises: an arbitration system configurable to apply an arbitration policy on the frame, wherein the arbitration policy dictates whether and at which order the switch uses the local flow table, local forwarding table, or both for processing the frame; wherein the arbitration policy is based on a priority associated with the software-defined data flow, wherein a value of the priority dictates the order at which the switch uses the local flow table, local forwarding table, or both for processing the frame; the switch further configured to change the value of the priority upon detecting a failure. logically partition a hybrid port into a first partition for frames belonging to the software-defined data flow and a second partition for frames belonging to the regular data flow; determine a frame received via said hybrid port as belonging to the software-defined flow or the regular data flow by checking one or more of: a virtual local area network (VLAN) tag or identifier; a type of a frame; and a flag in a header of a received frame; and if it is determined that the received frame belongs to the software-defined flow: control the frame based on the flow definition; or if it is determined that the received frame does not belong to the software-defined flow: perform a lookup on the frame in the local forwarding table to identify an output port; an arbitration system configurable to apply an arbitration policy on the frame, wherein the arbitration policy dictates whether and at which order the switch uses the local flow table, local forwarding table, or both for processing the frame; wherein the arbitration policy is based on a priority associated with the software-defined data flow, wherein a value of the priority dictates the order at which the switch uses the local flow table, local forwarding table, or both for processing the frame; the switch further configured to change the value of the priority upon detecting a failure.
A centrifugal pendulum absorber for a flywheel, comprising: - a plurality of pendulum weights being arranged circumferentially around a center axis of the centrifugal pendulum absorber, each pendulum weight being configured to be movable along a predetermined pendulum path during use, characterized in that, - the centrifugal pendulum absorber further comprises at least one stopping element for at least one of the pendulum weights which is positioned such that it defines an end point of the predetermined pendulum path, at which end point the at least one of the pendulum weights is configured to come into contact with the at least one stopping element, wherein at least a portion of the at least one stopping element which is intended to contact the at least one pendulum weight comprises a copper alloy, such as brass and/or bronze. - a plurality of pendulum weights being arranged circumferentially around a center axis of the centrifugal pendulum absorber, each pendulum weight being configured to be movable along a predetermined pendulum path during use, characterized in that, - the centrifugal pendulum absorber further comprises at least one stopping element for at least one of the pendulum weights which is positioned such that it defines an end point of the predetermined pendulum path, at which end point the at least one of the pendulum weights is configured to come into contact with the at least one stopping element, wherein at least a portion of the at least one stopping element which is intended to contact the at least one pendulum weight comprises a copper alloy, such as brass and/or bronze.
Profile for frames of windows, wall elements or doors which separate an interior space from an exterior space, having at least one metal profile (2, 3) extending in the longitudinal direction, wherein a plurality of openings for receiving or for leading through components are provided on at least one end wall (4, 5), which can face the interior space and/or the exterior space, of the metal profile (2, 3), and wherein the end wall (4, 5) has means for fastening a cover, characterized in that the profile is a composite profile, wherein the composite profile comprises at least two metal profiles (2, 3) which are arranged at a distance from one another and which are connected to one another.
A ventilator chamber for use in a ventilator circuit for administering medication to a patient, the ventilator chamber comprising: a housing comprising: a chamber defining an interior space having an input opening and an output opening; an input port defining an input passageway communicating with said input opening and adapted to receive a flow of gases from a ventilator intake line; a metered dose inhaler receptacle in fluid flow communication with said interior space; an output port defining an output passageway and communicating with said output opening; and an exhaust conduit communicating between and directly with said output passageway of said output port and said input passageway of input port; a one-way inhalation valve positioned to permit one-way flow from said input passageway of said input port to said interior space of said chamber housing; and a one-way exhaust valve located in said exhaust conduit, said one-way exhaust valve adapted to prevent a backflow of gas from said exhaust conduit into said output passageway, characterized in that said input port, said output port, and said metered dose inhaler receptacle are oriented in a non-parallel relationship to each other. a chamber defining an interior space having an input opening and an output opening; an input port defining an input passageway communicating with said input opening and adapted to receive a flow of gases from a ventilator intake line; a metered dose inhaler receptacle in fluid flow communication with said interior space; an output port defining an output passageway and communicating with said output opening; and an exhaust conduit communicating between and directly with said output passageway of said output port and said input passageway of input port; a one-way inhalation valve positioned to permit one-way flow from said input passageway of said input port to said interior space of said chamber housing; and a one-way exhaust valve located in said exhaust conduit, said one-way exhaust valve adapted to prevent a backflow of gas from said exhaust conduit into said output passageway, characterized in that said input port, said output port, and said metered dose inhaler receptacle are oriented in a non-parallel relationship to each other.
A support assembly comprising an anchor system, a support and a securing article to secure the support to the anchor system; the anchor system comprising: an anchor and a tendon arrangement; the anchor having an attaching formation to attach the tendon arrangement to the anchor, the tendon arrangement extending from the attaching formation as first and second passes (28, 30) of the tendon arrangement; wherein the tendon arrangement has opposite first and second end portions (24A, 26A); the system further including a joining arrangement (32, 34) to join the first and second end portions (24A, 26A) to each other; wherein the tendon arrangement comprises a looped region through which a securing article can extend, the tendon arrangement extending from the attaching formation to the looped region; characterised in that the tendon arrangement comprises an elongate member extending through the attaching formation to provide the first and second passes (28, 30); and the anchor system includes a protecting member defining a through hole, the protecting member being received within the attaching formation to receive the elongate member therethrough, and the elongate member extending through the hole. an anchor and a tendon arrangement; the anchor having an attaching formation to attach the tendon arrangement to the anchor, the tendon arrangement extending from the attaching formation as first and second passes (28, 30) of the tendon arrangement; wherein the tendon arrangement has opposite first and second end portions (24A, 26A); the system further including a joining arrangement (32, 34) to join the first and second end portions (24A, 26A) to each other; wherein the tendon arrangement comprises a looped region through which a securing article can extend, the tendon arrangement extending from the attaching formation to the looped region; characterised in that the tendon arrangement comprises an elongate member extending through the attaching formation to provide the first and second passes (28, 30); and the anchor system includes a protecting member defining a through hole, the protecting member being received within the attaching formation to receive the elongate member therethrough, and the elongate member extending through the hole.
A universal pipe joint, comprising a first connector, a second connector, and a connection mechanism, wherein the connection mechanism comprises an annular boss and a ring buckle buckled to the annular boss; the ring buckle can spin relative to the annular boss around its own center axis; the annular boss is in a fixed connection to the second connector; a first included angle is formed between the center axis of the annular boss and the center axis of the second connector; the ring buckle is in a fixed connection to the first connector; and a second included angle is formed between the center axis of the ring buckle and the center axis of the first connector,wherein the annular boss comprises an annular flange, and the ring buckle comprises a plurality of arc barbs for clamping the annular flange, and wherein the arc barbs are circumferentially distributed on an end of the ring buckle at intervals, characterized in that the outer wall of the second connector comprises an annular chime, the annular chime is in the vicinity of the arc barbs, and the outer diameter of the chime is slightly greater than or equal to the outer diameter of the ring buckle.
Housing unit for an electric machine, in particular for a PM servomotor, with a first bearing shield, with an intermediate flange and with a first stator laminated core, characterised in that the first bearing shield, the stator laminated core and the intermediate flange have a shared stainless steel coating, which is generated by means of an additive manufacturing method, wherein the housing unit is formed from the first bearing shield, the stator laminated core, the intermediate flange and the shared stainless steel coating.
A method of detecting brain injury in a test subject suspected of having a brain injury comprising: (a) contacting a blood sample obtained from the test subject with a probe that binds to ADAM10; and (b) detecting and/or quantifying the amount of ADAM10; wherein an increase in the amount of ADAM10 compared to a control is indicative of the test subject having suffered a brain injury; wherein the control is a reference baseline level of ADAM10 of the same test subject, a reference baseline level of ADAM10 of the general population, a reference baseline level of a population of similar age and/or of the same sex as the test subject, or a reference baseline level of ADAM10 of an athlete population off-season. (a) contacting a blood sample obtained from the test subject with a probe that binds to ADAM10; and (b) detecting and/or quantifying the amount of ADAM10; wherein an increase in the amount of ADAM10 compared to a control is indicative of the test subject having suffered a brain injury; wherein the control is a reference baseline level of ADAM10 of the same test subject, a reference baseline level of ADAM10 of the general population, a reference baseline level of a population of similar age and/or of the same sex as the test subject, or a reference baseline level of ADAM10 of an athlete population off-season.