A device, comprising: a housing; a communication module configured to send and receive information via at least wireless communication; a plurality of antennas (106A-D:106') configured to conduct the wireless communication; a plurality of sensors (108A-D:108') configured to sense device conditions and provide device condition information; and an antenna selection module (110:110':110") configured to cause at least one antenna in the plurality of antennas to be coupled to the communication module (212, wherein: the antenna selection module (110:110':110") comprises at least a multiplexer coupled to the communication module and the plurality of antennas (106A-D:106'), the multiplexer being configured to select the at least one antenna to be coupled to the communication module, the antenna selection module (110:110':110") further comprises a controller coupled to the plurality of sensors (108A-D:108') and the multiplexer; the plurality of sensors (108A-D:108') comprises: an orientation sensor to sense an orientation of the device and provide orientation information to said controller; a proximity sensor to sense a proximity of at least a portion of a human body and provide proximity information to said controller; a configuration sensor to sense a mechanical configuration of the housing and provide mechanical configuration information to said controller; and a motion sensor configured to sense motion of the device and provide motion information to said controller; and said controller is configured to control which of the plurality of antennas (106A-D:106') is selected by the multiplexer based at least in part on the device configuration information, wherein the device configuration information is a combination of primary device condition information and secondary device configuration information, the primary device condition information is said proximity information, said motion information, or a combination thereof, and said secondary device configuration information is said orientation information, said mechanical configuration information, or a combination thereof. a housing; a communication module configured to send and receive information via at least wireless communication; a plurality of antennas (106A-D:106') configured to conduct the wireless communication; a plurality of sensors (108A-D:108') configured to sense device conditions and provide device condition information; and an antenna selection module (110:110':110") configured to cause at least one antenna in the plurality of antennas to be coupled to the communication module (212, the antenna selection module (110:110':110") comprises at least a multiplexer coupled to the communication module and the plurality of antennas (106A-D:106'), the multiplexer being configured to select the at least one antenna to be coupled to the communication module, the antenna selection module (110:110':110") further comprises a controller coupled to the plurality of sensors (108A-D:108') and the multiplexer; the plurality of sensors (108A-D:108') comprises: an orientation sensor to sense an orientation of the device and provide orientation information to said controller; a proximity sensor to sense a proximity of at least a portion of a human body and provide proximity information to said controller; a configuration sensor to sense a mechanical configuration of the housing and provide mechanical configuration information to said controller; and an orientation sensor to sense an orientation of the device and provide orientation information to said controller; a proximity sensor to sense a proximity of at least a portion of a human body and provide proximity information to said controller; a configuration sensor to sense a mechanical configuration of the housing and provide mechanical configuration information to said controller; and a motion sensor configured to sense motion of the device and provide motion information to said controller; and said controller is configured to control which of the plurality of antennas (106A-D:106') is selected by the multiplexer based at least in part on the device configuration information, wherein the device configuration information is a combination of primary device condition information and secondary device configuration information, the primary device condition information is said proximity information, said motion information, or a combination thereof, and said secondary device configuration information is said orientation information, said mechanical configuration information, or a combination thereof.