mhurhangee/ep-ind-claims huggingface dataset:
Process for the preparation of a compound of the formula: and pharmaceutically acceptable addition salts thereof, comprising the following steps: step a) oxidation of [3-(bromomethyl)oxetan-3-yl]methanol of formula to form a compound of formula step b) conversion of carboxy group of a compound of formula to carbamate to form a compound of formula wherein R is C 1-6 alkyl, C 1-6 alkoxyphenyl-C x H 2x - or phenyl-C x H 2x -; wherein x is an integer selected from 1 to 6; step c) amination of a compound of formula to form a compound of formula wherein R is as defined above; step d) salt formation of a compound of formula with an acid to form a compound of formula wherein R is as defined above; step e) substitution reaction of a compound of formula with a compound of formula to give a compound of formula wherein R is as defined above; step f) substitution reaction of a compound of formula with a compound of formula to give a compound of formula (VIII) wherein R is as defined above; step g) comprises deprotection of a compound of formula (VIII) to give a compound of formula and if necessary, form a pharmaceutically acceptable addition salt. step a) oxidation of [3-(bromomethyl)oxetan-3-yl]methanol of formula to form a compound of formula step b) conversion of carboxy group of a compound of formula to carbamate to form a compound of formula wherein R is C 1-6 alkyl, C 1-6 alkoxyphenyl-C x H 2x - or phenyl-C x H 2x -; wherein x is an integer selected from 1 to 6; step c) amination of a compound of formula to form a compound of formula wherein R is as defined above; step d) salt formation of a compound of formula with an acid to form a compound of formula wherein R is as defined above; step e) substitution reaction of a compound of formula with a compound of formula to give a compound of formula wherein R is as defined above; step f) substitution reaction of a compound of formula with a compound of formula to give a compound of formula (VIII) wherein R is as defined above; step g) comprises deprotection of a compound of formula (VIII) to give a compound of formula and if necessary, form a pharmaceutically acceptable addition salt.
Connection device providing connection between a wiper blade and a driving arm (6, 7) for a vehicle, comprising a base adapter and at least a first adapter, this base adapter being equipped with at least one pivot member intended to connect it to a connector, the base adapter being configured to connect this connector to a first type of driving arm, the base adapter and the first adapter each having a U-shaped cross section formed of two lateral walls (251, 252, 261, 262) connected by an upper wall (250, 260), at least one lateral wall (251, 252) of the base adapter comprising at least one clearance (501, 502) which accepts a lateral wall (261, 262) of the first adapter, this connection device being characterized in that each lateral wall of the base adapter and the first adapter (251, 252, 261, 262) comprises bearing zones (503, 504, 505, 506), these bearing zones being rectangular strips projecting from the external faces (551, 552, 561, 562) of the lateral walls (251, 252, 261, 262).
A dust collecting device that can be attached to an impact tool and collects dust generated by the impact tool in which a hammer bit coupled to a front end region of a tool body is caused to rectilinearly move in an axial direction of the hammer bit for performing a chipping operation on a workpiece, wherein the axial direction defines a front-rear-direction of the dust collecting device when attached to the impact tool, the dust collecting device comprising: a dust suction port through which dust is sucked up and which can be adjusted in position in the axial direction of the hammer bit according to a length of the hammer bit in the axial direction, and a bit covering which is arranged to surround the hammer bit, wherein the bit covering comprises a plurality of cylindrical members (173a, 173b) which are fitted one on the other and can be moved relative to each other in the axial direction of the tool bit, wherein the plurality of cylindrical members comprises at least a front cylindrical member and a rear cylindrical member, a front opening of the front cylindrical member defines the dust suction port, and the position of the dust suction port can be adjusted by relative movement of the cylindrical members (173a, 173b) and can be fixed by engagement of a projection (174b; 177a; 179a) formed on one of the cylindrical members (173a, 173b), which are fitted one on the other, with a recess (177b; 179b) or female thread formed on the other of the cylindrical members (173a, 173b), which are fitted one on the other, according to the length of the hammer bit which is selectively coupled to the front region of the tool body. a dust suction port through which dust is sucked up and which can be adjusted in position in the axial direction of the hammer bit according to a length of the hammer bit in the axial direction, and a bit covering which is arranged to surround the hammer bit, wherein the bit covering comprises a plurality of cylindrical members (173a, 173b) which are fitted one on the other and can be moved relative to each other in the axial direction of the tool bit, wherein the plurality of cylindrical members comprises at least a front cylindrical member and a rear cylindrical member, a front opening of the front cylindrical member defines the dust suction port, and the position of the dust suction port can be adjusted by relative movement of the cylindrical members (173a, 173b) and can be fixed by engagement of a projection (174b; 177a; 179a) formed on one of the cylindrical members (173a, 173b), which are fitted one on the other, with a recess (177b; 179b) or female thread formed on the other of the cylindrical members (173a, 173b), which are fitted one on the other, according to the length of the hammer bit which is selectively coupled to the front region of the tool body.
A path computation method, comprising: receiving, by a second network device, path requirement information and a recomputation condition that are sent by a first network device; computing, by the second network device, a path meeting a requirement according to the path requirement information; sending, by the second network device, first description information to the first network device, wherein the first description information is description information of the path meeting the requirement; determining, by the second network device, whether the recomputation condition is met, wherein the recomputation condition is associated with a current network performance parameter change rate on the path meeting the requirement; performing, by the second network device, path recomputation when the recomputation condition is met; and sending, by the second network device, second description information to the first network device, wherein the second description information is description information of a path obtained by means of recomputation. receiving, by a second network device, path requirement information and a recomputation condition that are sent by a first network device; computing, by the second network device, a path meeting a requirement according to the path requirement information; sending, by the second network device, first description information to the first network device, wherein the first description information is description information of the path meeting the requirement; determining, by the second network device, whether the recomputation condition is met, wherein the recomputation condition is associated with a current network performance parameter change rate on the path meeting the requirement; performing, by the second network device, path recomputation when the recomputation condition is met; and sending, by the second network device, second description information to the first network device, wherein the second description information is description information of a path obtained by means of recomputation.
A synthetic optical image system, comprising an array of focusing elements, and an image system including an array of microstructured icon elements designed to collectively form an image, wherein the array of focusing elements and the image system cooperate to form a synthetic optical image, wherein the array of microstructured icon elements is incorporated into an icon layer, wherein the microstructured icon elements are holographic surface relief patterns, and/or diffractive relief patterns, and wherein the icon layer is laminated with laminating adhesive to a coating material layer, wherein the laminating adhesive is in contact with the microstructured icon elements, wherein the microstructured icon elements are unfilled or not completely filled.
A computer-implemented method for performing customizable machine prediction, the method comprising: receiving a specification comprising at least features of a trained machine learning model; generating an application programming interface, API, for the trained machine learning model based on the received specification; loading the trained machine learning model to a software service using the generated interface, the trained machine learning model comprising a binary file configured to receive data as input and generate prediction data as output; generating predictions using observed data that is stored according to a multidimensional data model, wherein a portion of the observed data is input to the trained machine learning model that has been loaded to generate first data predictions, and a portion of the observed data is used by a generic forecast model to generate second data predictions; and displaying the first data predictions and the second data predictions in a user interface configured to display intersections of the multidimensional data model. receiving a specification comprising at least features of a trained machine learning model; generating an application programming interface, API, for the trained machine learning model based on the received specification; loading the trained machine learning model to a software service using the generated interface, the trained machine learning model comprising a binary file configured to receive data as input and generate prediction data as output; generating predictions using observed data that is stored according to a multidimensional data model, wherein a portion of the observed data is input to the trained machine learning model that has been loaded to generate first data predictions, and a portion of the observed data is used by a generic forecast model to generate second data predictions; and displaying the first data predictions and the second data predictions in a user interface configured to display intersections of the multidimensional data model.
Brush for cleaning surfaces, comprising at least a central support which extends along a longitudinal axis between two opposite ends (13a, 13b), and a plurality of tufts of bristles projecting outward from said central support and disposed according to an ordered disposition on said central support, wherein said tufts of bristles are disposed along distribution directrices (P, P1, P2, P3, P4) extending longitudinally on said brush between said opposite ends (13a, 13b) of said central support, wherein said tufts of bristles are grouped into groups, distributed around said central support, and all the tufts of bristles of the same group have the same inclination with respect to said central support, wherein any distribution directrix (P, P1, P2, P3, P4) of the tufts of bristles between said opposite ends (13a, 13b) of said central support, along which said tufts of bristles arc distributed, comprises tufts (14a, 14b, 14c, 14d, 14n) of bristles belonging to at least two different groups (15a, 15b, 15c, 15d, 15n), having inclinations (A1, A2, A3, A4, An) that differ with respect to each other and in that corresponding tufts (14a, 14b, 14c, 14d) of bristles disposed on at least two different distribution directrices (P, P1, P2, P3, P4) have an inclination (A1, A2, A3, A4) that differs one from the others, said tufts (14a, 14b, 14c, 14d) of bristles belonging to different groups (15a, 15b, 15c, 15d), wherein each distribution directrix (P, P1, P2, P3, P4) of the tufts of bristles between said opposite ends (13a, 13b) of said central support, along which said tufts of bristles are distributed, comprises tufts (14a, 14b, 14c, 14d, 14n) of bristles belonging to at least three different groups (15a, 15b, 15c, 15d, 15n), having inclinations (A1, A2, A3, A4, An) that differ one from the others said brush being characterized in that on the same distribution directrix (P, P1, P2, P3, P4), the tufts of bristles of one group vary their inclination by a determinate angle with respect to the inclination of the tufts of bristles of another group, wherein said tufts (14a, 14b) are disposed adjacent and aligned in a row, that is, consecutive one after the other, along said longitudinal distribution directrix (P, P1, P2, P3, P4), said tufts (14a, 14b) of different groups (15a, 15b, 15c, 15d, 15n) being also inclined differently from each other.
A radio base station (MMeNB) for forming a narrow-area cell to communicate with a user terminal in a radio communication system where the narrow-area cell is provided inside a wide-area cell, comprising: a reference signal generating section configured to generate a reference signal; a carrier frequency correction information calculating section configured to calculate carrier frequency correction information which is information to correct a carrier frequency of the narrow-area cell, based on a wide-area radio signal; a sampling frequency correction information calculating section configured to calculate sampling frequency correction information which is information to correct a sampling frequency of a baseband signal of the narrow-area cell, based on the wide-area radio signal; a carrier frequency synthesizer configured to generate a carrier frequency of the narrow-area cell based on the reference signal and the carrier frequency correction information; and a sampling frequency synthesizer configured to generate a sampling frequency of a baseband signal of the narrow-area cell based on the reference signal and the sampling frequency correction information. a reference signal generating section configured to generate a reference signal; a carrier frequency correction information calculating section configured to calculate carrier frequency correction information which is information to correct a carrier frequency of the narrow-area cell, based on a wide-area radio signal; a sampling frequency correction information calculating section configured to calculate sampling frequency correction information which is information to correct a sampling frequency of a baseband signal of the narrow-area cell, based on the wide-area radio signal; a carrier frequency synthesizer configured to generate a carrier frequency of the narrow-area cell based on the reference signal and the carrier frequency correction information; and a sampling frequency synthesizer configured to generate a sampling frequency of a baseband signal of the narrow-area cell based on the reference signal and the sampling frequency correction information.
A three-dimensional bioabsorbable adjunct (800, 1200, 1300, 1400, 1500) for use with a stapling assembly, comprising: a plurality of resilient struts (816, 1216, 1316, 1416, 1516) that are formed of a first matrix comprising at least one fused bioabsorbable polymer, the plurality of resilient struts forming repeating geometric units, and the plurality of resilient struts being configured to deform when compressed, wherein the adjunct is configured to be releasably retained on a stapling body, and to allow a plurality of staples disposed within the stapling body to pass therethrough such that the adjunct can be attached to tissue by the plurality of staples; wherein the plurality of resilient struts are interconnected at nodes (814, 822, 1222, 1314, 1322, 1422, 1514, 1522) to form truss-like structures that are configured to bend when compressed; and characterised in that the nodes are formed of a second matrix comprising at least one fused bioabsorbable polymer that differs from the at least one fused bioabsorbable polymer of the first matrix; and wherein the three-dimensional bioabsorbable adjunct further comprises at least one stop element configured to limit an amount of compression of the adjunct. a plurality of resilient struts (816, 1216, 1316, 1416, 1516) that are formed of a first matrix comprising at least one fused bioabsorbable polymer, the plurality of resilient struts forming repeating geometric units, and the plurality of resilient struts being configured to deform when compressed, wherein the adjunct is configured to be releasably retained on a stapling body, and to allow a plurality of staples disposed within the stapling body to pass therethrough such that the adjunct can be attached to tissue by the plurality of staples; wherein the plurality of resilient struts are interconnected at nodes (814, 822, 1222, 1314, 1322, 1422, 1514, 1522) to form truss-like structures that are configured to bend when compressed; and characterised in that the nodes are formed of a second matrix comprising at least one fused bioabsorbable polymer that differs from the at least one fused bioabsorbable polymer of the first matrix; and wherein the three-dimensional bioabsorbable adjunct further comprises at least one stop element configured to limit an amount of compression of the adjunct.
A method for producing rod-like articles of the tobacco industry wherein a first cutting is carried out in which a continuous rod is cut by means of a first cutting unit into a train of double rod-like articles, the direction of conveying the double rod-like articles is changed from a first direction along the axis of the rod-like articles to a second direction transverse to the axis of the rod-like articles, at least each time two double rod-like articles being transferred into grooves of a drum conveyor, and at least two input streams (S1, S2) of the double rod-like articles being formed, at least two streams (S1, S2) of the double rod-like articles are transformed into one intermediate stream of double rod-like articles by moving a double rod-like article from one of the streams (S1, S2) between two double rod-like articles of the other of the streams (S1, S2), the geometric centres of the double rod-like articles in the intermediate stream being disposed in a plane (k) parallel to the second direction, a second cutting is carried out wherein the double rod-like articles conveyed in the intermediate stream of the double rod-like articles are cut into two single rod-like articles by means of a second cutting unit to form two output streams (S4, S5) of single rod-like articles. a first cutting is carried out in which a continuous rod is cut by means of a first cutting unit into a train of double rod-like articles, the direction of conveying the double rod-like articles is changed from a first direction along the axis of the rod-like articles to a second direction transverse to the axis of the rod-like articles, at least each time two double rod-like articles being transferred into grooves of a drum conveyor, and at least two input streams (S1, S2) of the double rod-like articles being formed, at least two streams (S1, S2) of the double rod-like articles are transformed into one intermediate stream of double rod-like articles by moving a double rod-like article from one of the streams (S1, S2) between two double rod-like articles of the other of the streams (S1, S2), the geometric centres of the double rod-like articles in the intermediate stream being disposed in a plane (k) parallel to the second direction, a second cutting is carried out wherein the double rod-like articles conveyed in the intermediate stream of the double rod-like articles are cut into two single rod-like articles by means of a second cutting unit to form two output streams (S4, S5) of single rod-like articles.
A filter test strip to filter and test a specimen in liquid, comprising: a test element; and a specimen filter assembly which is located on the test element and includes: at least one filter cotton holding layer; at least one filter cotton layer; and at least one cotton bonding layer; wherein the filter cotton holding layer includes a filter channel to allow the specimen in liquid to pass through and to hold the filter cotton layer in the filter channel, wherein a gap is formed between the filter cotton holding layer and filter cotton layer, and the cotton bonding layer is bonded to a lower side of the filter cotton holding layer via an adhesive; characterized in that the adhesive on the cotton bonding layer fully covers a circumference of the filter cotton layer and masks the gap between the filter cotton holding layer and filter cotton layer. a test element; and a specimen filter assembly which is located on the test element and includes: at least one filter cotton holding layer; at least one filter cotton layer; and at least one cotton bonding layer; wherein the filter cotton holding layer includes a filter channel to allow the specimen in liquid to pass through and to hold the filter cotton layer in the filter channel, wherein a gap is formed between the filter cotton holding layer and filter cotton layer, and the cotton bonding layer is bonded to a lower side of the filter cotton holding layer via an adhesive; at least one filter cotton holding layer; at least one filter cotton layer; and at least one cotton bonding layer; wherein the filter cotton holding layer includes a filter channel to allow the specimen in liquid to pass through and to hold the filter cotton layer in the filter channel, wherein a gap is formed between the filter cotton holding layer and filter cotton layer, and the cotton bonding layer is bonded to a lower side of the filter cotton holding layer via an adhesive; characterized in that the adhesive on the cotton bonding layer fully covers a circumference of the filter cotton layer and masks the gap between the filter cotton holding layer and filter cotton layer.
Profile machining device, comprising at least one tool for profile machining, at least one clamping device for a profile to be machined, and an advancing device for moving a profile to be machined through the profile machining device along a transport direction corresponding to a longitudinal direction of the profile, wherein the tool is disposed on a tool holder, and wherein the tool and the tool holder are configured to machine the profile essentially on all sides, wherein the clamping device includes at least one plate clamp for fixing a profile to be machined during a profile machining procedure using the tool and at least one roller clamp (26, 30) for guiding the profile during a profile machining procedure of the tool with simultaneous moving of the profile using the advancing device, characterized in that the tool holder is displaceable in and counter a longitudinal direction of a profile to be machined, and in that means are provided for setting a first operation mode, wherein the profile to be machined is fixed relative to a machine frame using the plate clamps, or a second operation mode, wherein the profile to be machined is guided using at least one of the roller clamps (26, 30) and the profile is moved using the advancing device.