A compound of Formula: in which: R 1 is selected from the group consisting of a substituted aryl, substituted or unsubstituted arylalkyl and substituted or unsubstituted heteroaryl; X is selected from the group consisting of a C and N atom; Y is selected from the group consisting of CO and SO 2; R 2, R 3 and R 4 are independently selected from the group consisting of, H, OH, substituted or unsubstituted aryl, substituted or unsubstituted arylalkyl, substituted or unsubstituted linear, cyclic or branched alkyl, cyano, and perfluoroalkyl; and R 5 is selected from the group consisting of H, halogen, alkyl, cyano and null, wherein R 5 is null when X is N, and optionally wherein R 2, R 4, Y and N form a substituted or unsubstituted 4-7 member saturated ring, and optionally wherein R 2, R 3 and N form a substituted or unsubstituted 4-7 member saturated ring, for use for protecting a patient from a bacterial infection; wherein, when substituted, an aryl group may have up to three substituents selected from the group consisting of halogen, cyano, (C 1 - 6)alkyl, mono to perfluoro(C 1 - 3)alkyl, (C 3 - 7)cycloalkyl, (C 2 - 6)alkenyl, (C 1 - 6)alkoxy, (C 2 - 6)alkenoxy, aryl(C 1 - 6)alkoxy, halo(C 1 - 6)alkyl, hydroxy, amino, mono- or di-(C 1 - 6)alkylamino, acylamino, nitro, carboxy, (C 1 - 6)alkoxycarbonyl, (C 1 - 6)alkenyloxycarbonyl, (C 1-6)alkoxycarbonyl(C 1 - 6)alkyl, carboxy(C 1 - 6)alkyl, (C 1 - 6)alkylcarbonyloxy, carboxy(C 1 - 6)alkyloxy, (C 1 - 6)alkoxycarbonyl(C 1 - 6)alkoxy, (C 1 - 6)alkylthio, (C 1 - 6)alkylsulphinyl, (C 1 - 6)alkylsulphonyl, sulphamoyl, mono- and di-(C 1 - 6)-alkylsulphamoyl, carbamoyl, mono- and di-(C 1-6)alkylcarbamoyl, heteroaryl and heterocyclyl; wherein when substituted, a heteroaryl or a heterocyclyl group may have up to three substituents, each substituent being selected from the group consisting of halogen, cyano, (C 1 - 6)alkyl, mono to perfluoro(C 1 - 3)alkyl, (C 3 - 7)cycloalkyl, (C 2 - 6)alkenyl, (C 1 - 6)alkoxy, (C 2 - 6)alkenoxy, aryl(C 1 - 6)alkoxy, halo(C 1 - 6)alkyl, hydroxy, amino, mono- or di-(C 1 - 6)alkylamino, acylamino, nitro, carboxy, (C 1 - 6)alkoxycarbonyl, (C 1 - 6)alkenyloxycarbonyl, (C 1 - 6)alkoxycarbonyl(C 1 - 6)alkyl, carboxy(C 1 - 6)alkyl, (C 1 - 6)alkylcarbonyloxy, carboxy(C 1 - 6)alkyloxy, (C 1 - 6)alkoxycarbonyl(C 1 - 6)alkoxy, (C 1 - 6)alkylthio, (C 1 - 6)alkylsulphinyl, (C 1 - 6)alkylsulphonyl, sulphamoyl, mono- and di-(C 1 - 6)-alkylsulphamoyl, carbamoyl, mono- and di-(C 1 - 6)alkylcarbamoyl, heteroaryl, heterocyclyl and oxo; and wherein the substituent of a substituted alkyl moiety is selected from the group consisting of halogen, cyano, azido, nitro, carboxy, (C 1 - 6)alkoxycarbonyl, carbamoyl, mono- or di-(C 1-6)alkylcarbamoyl, sulpho, sulphamoyl, mono- or di-(C 1-6)alkylsulphamoyl, mono- or di-(C 1 - 6)alkylamino, acylamino, ureido, (C 1 - 6)alkoxycarbonylamino, 2,2,2-trichloroethoxycarbonylamino, aryl, heteroaryl, heterocyclyl, hydroxy, (C 1 - 6)alkoxy, acyloxy, oxo, acyl, 2-thienoyl, (C 1 - 6)alkylthio, (C 1 - 6)alkylsulphinyl, (C 1 - 6)alkylsulphonyl, hydroxyimino, (C 1 - 6)alkoxyimino, hydrazino, hydrazono, benzohydroximoyl, guanido, amidino, iminoalkylamino,. alkylthioalkoxycarbinyl, and alkylsulfonyl, 4-formyl-piperazine-1-yl, 4-methyl-piperazine-1-yl, 4-ethylpiperazin-1-yl, 4-phenylpiperazin-1-yl, 4-pyrimidin-2-yl-piperazin-1-yl, Hexahydroxy-pyrrolo[1,2-a]imidazole-1-yl, Morpholin-4-yl, 3-(2-methoxy-ethyl)-methyl-amino, and 3-(2-methoxy-ethyl)-methyl-amino. R 1 is selected from the group consisting of a substituted aryl, substituted or unsubstituted arylalkyl and substituted or unsubstituted heteroaryl; X is selected from the group consisting of a C and N atom; Y is selected from the group consisting of CO and SO 2; R 2, R 3 and R 4 are independently selected from the group consisting of, H, OH, substituted or unsubstituted aryl, substituted or unsubstituted arylalkyl, substituted or unsubstituted linear, cyclic or branched alkyl, cyano, and perfluoroalkyl; and R 5 is selected from the group consisting of H, halogen, alkyl, cyano and null, wherein R 5 is null when X is N, and optionally wherein R 2, R 4, Y and N form a substituted or unsubstituted 4-7 member saturated ring, and optionally wherein R 2, R 3 and N form a substituted or unsubstituted 4-7 member saturated ring, for use for protecting a patient from a bacterial infection;