mhurhangee/ep-ind-claims huggingface dataset:
A recombinant, artificial or engineered metabolic pathway in a cell free system or a microorganism comprising a plurality of enzymatic steps that converts a substrate to a product, wherein the pathway includes an unbalanced production and utilization of a first co-factor, said pathway comprising: a first co-factor-dependent enzyme that is capable of converting a first substrate to a second substrate, said enzyme producing the unbalanced production and utilization of a first cofactor; a second co-factor-dependent enzyme that is also capable of converting the first substrate to the second substrate, wherein the second cofactor-dependent enzyme is a mutant of the first co-factor-dependent enzyme that has been modified to have its cofactor preference altered to a second cofactor; and an enzyme that recycles the first cofactor, wherein the first co-factor comprises NAD + /NADH and the second co-factor comprises NADP + /NADPH and wherein the pathway comprises a NADH dehydrogenase, a NADPH dehydrogenase that is a mutant NADH dehydrogenase that utilizes NADP+ instead of NAD+, and a NADH oxidase. a first co-factor-dependent enzyme that is capable of converting a first substrate to a second substrate, said enzyme producing the unbalanced production and utilization of a first cofactor; a second co-factor-dependent enzyme that is also capable of converting the first substrate to the second substrate, wherein the second cofactor-dependent enzyme is a mutant of the first co-factor-dependent enzyme that has been modified to have its cofactor preference altered to a second cofactor; and an enzyme that recycles the first cofactor, wherein the first co-factor comprises NAD + /NADH and the second co-factor comprises NADP + /NADPH and wherein the pathway comprises a NADH dehydrogenase, a NADPH dehydrogenase that is a mutant NADH dehydrogenase that utilizes NADP+ instead of NAD+, and a NADH oxidase.
A production optimization device of a component mounting line in which components are mounted on a circuit board using component mounting machines, comprising: intra present property optimization means for optimizing production of the component mounting line under conditions in which a selection range of members of the mounting line to use in the production is restricted to within a range of members actually owned by a user; second optimization means for optimizing the production of the component mounting line under conditions in which restriction of the selection range of the members of the mounting line to use in the production is removed for at least a subset of the members; and display means for displaying optimization results of the intra present property optimization means compared to the optimization results of the second optimization means, wherein the display means is configured to display at least one of a total production time, a cycle time, a number of set-up changes, and a total set-up changing time, respectively, as the optimization results of the intra present property optimization means and the optimization results of the second optimization means. intra present property optimization means for optimizing production of the component mounting line under conditions in which a selection range of members of the mounting line to use in the production is restricted to within a range of members actually owned by a user; second optimization means for optimizing the production of the component mounting line under conditions in which restriction of the selection range of the members of the mounting line to use in the production is removed for at least a subset of the members; and display means for displaying optimization results of the intra present property optimization means compared to the optimization results of the second optimization means, wherein the display means is configured to display at least one of a total production time, a cycle time, a number of set-up changes, and a total set-up changing time, respectively, as the optimization results of the intra present property optimization means and the optimization results of the second optimization means.
Method for detecting a combustion process in an internal combustion engine, which has a crankshaft, of a hybrid vehicle, comprising: acquiring a rotational speed signal (30, 31) which represents a rotational speed of the crankshaft; acquiring a crankshaft angle signal which represents a crankshaft angle of the crankshaft; and determining, on the basis of the rotational speed signal (30, 31) and the crankshaft angle signal, whether combustion is taking place in the internal combustion engine, wherein the determining comprises detecting, on the basis of the rotational speed signal, a rotational speed profile which contains a dead centre rotational speed (n T50, n T51), which is reached when a cylinder piston of the internal combustion engine is at a top dead centre in a working stroke, and a rotational speed maximum (53, 54), and determining a maximum increase in the rotational speed from the dead centre rotational speed (n T50, n T51) up to the rotational speed maximum (53, 54), characterized in that the determining also comprises determining a reference rotational speed (n B50, n B51) at which a predefined percentage of the maximum increase is reached, and determining a reference crankshaft angle (φ B50, φ B51) which is associated with the reference rotational speed (n B50, n B51), and the determining of whether combustion is taking place is carried out on the basis of a threshold angle (φ S) the reference crankshaft angle (φ B50, φ B51) is compared with the threshold angle (φ S) and it is detected that combustion is taking place when the reference crankshaft angle (φ B50, φ B51) exceeds the threshold angle (φ S). acquiring a rotational speed signal (30, 31) which represents a rotational speed of the crankshaft; acquiring a crankshaft angle signal which represents a crankshaft angle of the crankshaft; and determining, on the basis of the rotational speed signal (30, 31) and the crankshaft angle signal, whether combustion is taking place in the internal combustion engine, wherein the determining comprises detecting, on the basis of the rotational speed signal, a rotational speed profile which contains a dead centre rotational speed (n T50, n T51), which is reached when a cylinder piston of the internal combustion engine is at a top dead centre in a working stroke, and a rotational speed maximum (53, 54), and determining a maximum increase in the rotational speed from the dead centre rotational speed (n T50, n T51) up to the rotational speed maximum (53, 54),
An optical article having antistatic and antireflection or reflective properties, comprising a substrate having at least one main surface coated with an antireflection or reflective coating, said coating comprising at least one electrically conductive layer, wherein: - said electrically conductive layer comprises at least 30% by weight of tin oxide, SnO 2, relative to the total weight of the electrically conductive layer, - the deposition of said electrically conductive layer has been performed under ionic assistance: o either in a vacuum chamber under a residual pressure varying from 6.10 -5 mbar to 2.10 -4 mbar, o or under an acceleration voltage ranging from 50 to 200 V, and - said substrate has a water uptake rate equal to or greater than 0.6% by weight relative to the total weight of said substrate, the water uptake rate being measured after predrying said substrate and then storing it for 800 hours in a chamber at 50°C under 100% relative humidity and at atmospheric pressure. - said electrically conductive layer comprises at least 30% by weight of tin oxide, SnO 2, relative to the total weight of the electrically conductive layer, - the deposition of said electrically conductive layer has been performed under ionic assistance: o either in a vacuum chamber under a residual pressure varying from 6.10 -5 mbar to 2.10 -4 mbar, o or under an acceleration voltage ranging from 50 to 200 V, and o either in a vacuum chamber under a residual pressure varying from 6.10 -5 mbar to 2.10 -4 mbar, o or under an acceleration voltage ranging from 50 to 200 V, and - said substrate has a water uptake rate equal to or greater than 0.6% by weight relative to the total weight of said substrate, the water uptake rate being measured after predrying said substrate and then storing it for 800 hours in a chamber at 50°C under 100% relative humidity and at atmospheric pressure.
An apparatus comprising: a handwriting input device adapted to receive input stroke data; a processor; a memory; and a stroke data storage module, wherein the stroke data storage module is configured to identify a handwritten character from the stroke data, map the handwritten character to a user-specific font character based on the stroke data, and create a file storing a character encoding corresponding to the handwritten character mapped to the user-specific font character, characterized in that, the stroke data storage module is further configured to determine a deviation between the handwritten character and a model character, wherein the stroke data storage module is further adapted to store the deviation in the file. a handwriting input device adapted to receive input stroke data; a processor; a memory; and a stroke data storage module, wherein the stroke data storage module is configured to identify a handwritten character from the stroke data, map the handwritten character to a user-specific font character based on the stroke data, and create a file storing a character encoding corresponding to the handwritten character mapped to the user-specific font character, characterized in that, the stroke data storage module is further configured to determine a deviation between the handwritten character and a model character, wherein the stroke data storage module is further adapted to store the deviation in the file.
An in vitro method for selecting human mesenchymal lineage precursor or stem cells for use in treatment comprising: (i) culturing an obtained population of cells comprising human mesenchymal lineage precursor or stem cells; (ii) determining the amount of TGFβ1 released by the human mesenchymal lineage precursor or stem cells into the culture medium; and (iii) selecting for use in treatment the human mesenchymal lineage precursor or stem cells that release TGFβ1 into the culture medium in an amount of at least 2800 pg/10 6 cells. (i) culturing an obtained population of cells comprising human mesenchymal lineage precursor or stem cells; (ii) determining the amount of TGFβ1 released by the human mesenchymal lineage precursor or stem cells into the culture medium; and (iii) selecting for use in treatment the human mesenchymal lineage precursor or stem cells that release TGFβ1 into the culture medium in an amount of at least 2800 pg/10 6 cells.
A method of producing a vessel (10, 20, 30) useful for gravimetric testing, the vessel (10, 20, 30) comprising a main body having an open top end (12, 22, 32) and a sealed bottom end (16, 26, 36) to define an inner cavity configured to hold a volume of liquid, the main body comprising a polymeric material having a melting temperature greater than 180°C, the method characterized by: performing at least two preconditioning steps on the vessel; and applying an indicia to a portion of the main body of the vessel, wherein the indicia include a tare weight of the vessel, wherein the tare weight of the vessel comprises a weight measured after a subsequent preconditioning step yields a weight variation of less than 0.5 mg from a weight recorded from a previous preconditioning step, wherein the at least two preconditioning steps comprises heating the vessel to at least 180°C for a specific length of time. performing at least two preconditioning steps on the vessel; and applying an indicia to a portion of the main body of the vessel, wherein the indicia include a tare weight of the vessel,
A camellia japonica saponin for use in preventing, inhibiting or treating coronavirus infection, wherein the camellia japonica saponin is extracted from oil press cake of seeds of camellia japonica, wherein the coronavirus is severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), wherein the camellia japonica saponin comprises camellia japonica saponin A1, camellia japonica saponin A2, camellia japonica saponin B 1, camellia japonica saponin B2, camellia japonica saponin C1, or a combination thereof. wherein the coronavirus is severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), wherein the camellia japonica saponin comprises camellia japonica saponin A1, camellia japonica saponin A2, camellia japonica saponin B 1, camellia japonica saponin B2, camellia japonica saponin C1, or a combination thereof.
A planetary gear system including a pin for coupling a planet gear to a carrier, the pin comprising: a first end and a second end; the pin being supported by the carrier at only one end of said first and second ends (52,54) such that the pin is cantilevered; an outer surface of the pin extending between the first end and the second end; wherein the outer surface comprises a first end surface extending from the first end and an intermediate surface extending from the first end surface, the first end surface being configured for interfacing with the carrier, the pin further comprising: means for modifying the compliance of the pin at the interface between the pin and the carrier; the means for modifying the compliance of the pin comprising opposing channels positioned on opposite sides of the pin with no channels or other features connecting the opposing channels; wherein the means for modifying the compliance of the pin allows greater compliance of the pin in the tangential direction than in the radial direction; characterized in that: the means for modifying the compliance of the pin includes a bore hole extending through the outer surface generally transverse to a central planet axis. a first end and a second end; the pin being supported by the carrier at only one end of said first and second ends (52,54) such that the pin is cantilevered; an outer surface of the pin extending between the first end and the second end; wherein the outer surface comprises a first end surface extending from the first end and an intermediate surface extending from the first end surface, the first end surface being configured for interfacing with the carrier, the pin further comprising: means for modifying the compliance of the pin at the interface between the pin and the carrier; the means for modifying the compliance of the pin comprising opposing channels positioned on opposite sides of the pin with no channels or other features connecting the opposing channels; wherein the means for modifying the compliance of the pin allows greater compliance of the pin in the tangential direction than in the radial direction; characterized in that: the means for modifying the compliance of the pin includes a bore hole extending through the outer surface generally transverse to a central planet axis. means for modifying the compliance of the pin at the interface between the pin and the carrier; the means for modifying the compliance of the pin comprising opposing channels positioned on opposite sides of the pin with no channels or other features connecting the opposing channels; wherein the means for modifying the compliance of the pin allows greater compliance of the pin in the tangential direction than in the radial direction; characterized in that: the means for modifying the compliance of the pin includes a bore hole extending through the outer surface generally transverse to a central planet axis.
An oven range comprising: an oven chamber; a door for selectively opening or closing the oven chamber, a heating chamber in which a heating source for cooking the food within the oven chamber is disposed; at least one communication opening for allowing the oven chamber to communicate with the heating chamber; and an opening/closing device for selectively opening or closing the communication opening, characterized in that the opening/closing device opens the communication opening when the oven chamber is closed by the oven door, and the opening/closing device closes the communication opening when the oven chamber is opened by the oven door. an oven chamber; a door for selectively opening or closing the oven chamber, a heating chamber in which a heating source for cooking the food within the oven chamber is disposed; at least one communication opening for allowing the oven chamber to communicate with the heating chamber; and an opening/closing device for selectively opening or closing the communication opening, characterized in that the opening/closing device opens the communication opening when the oven chamber is closed by the oven door, and the opening/closing device closes the communication opening when the oven chamber is opened by the oven door.
Method of applying a field grading layer to a power cable, wherein it comprises the following steps: i) preparing a polymer composition comprising a polymer matrix, at least one conductive filler different from a non-linear conductive organic filler, and at least one crosslinking agent, * said conductive filler being a linear or non-linear inorganic conductive filler selected from metal oxides, ceramics, carbon nanotubes, SiC, graphene oxide and mixtures thereof, or a linear organic conductive filler selected from intrinsically conducting polymers, and * said polymer matrix being different from an elastomer matrix, ii) extruding the polymer composition into a crosslinkable field grading tape, iii) winding the crosslinkable field grading tape onto a section of power cable in need of field grading, and iv) crosslinking the crosslinkable tape to obtain a field grading layer. i) preparing a polymer composition comprising a polymer matrix, at least one conductive filler different from a non-linear conductive organic filler, and at least one crosslinking agent, * said conductive filler being a linear or non-linear inorganic conductive filler selected from metal oxides, ceramics, carbon nanotubes, SiC, graphene oxide and mixtures thereof, or a linear organic conductive filler selected from intrinsically conducting polymers, and * said polymer matrix being different from an elastomer matrix, * said conductive filler being a linear or non-linear inorganic conductive filler selected from metal oxides, ceramics, carbon nanotubes, SiC, graphene oxide and mixtures thereof, or a linear organic conductive filler selected from intrinsically conducting polymers, and * said polymer matrix being different from an elastomer matrix, ii) extruding the polymer composition into a crosslinkable field grading tape, iii) winding the crosslinkable field grading tape onto a section of power cable in need of field grading, and iv) crosslinking the crosslinkable tape to obtain a field grading layer.
A guiding ancillary intended to cooperate with at least two bone surfaces (11, 12), characterised in that it comprises: - For each bone surface, a bearing surface which is an impression of a portion of the corresponding bone surface to at least partially match a portion of the corresponding bone surface; said bearing surface delimiting a working area on said bone surface when it is in contact with said bone surface; - said bearing surfaces being configured to hold said ancillary in position on the corresponding bone surfaces and - At least one guide means (13, 14, 15, 16, 17, 18, 19, 20) capable of receiving at least one medical device, said at least one guide means guiding the medical device towards said working area on the corresponding bone surface, each guide means defining a working axis (131, 141, 151, 161, 171, 181, 191) for moving the medical device along said working axis, said working area being determined by said working axes. - For each bone surface, a bearing surface which is an impression of a portion of the corresponding bone surface to at least partially match a portion of the corresponding bone surface; said bearing surface delimiting a working area on said bone surface when it is in contact with said bone surface; - said bearing surfaces being configured to hold said ancillary in position on the corresponding bone surfaces and - At least one guide means (13, 14, 15, 16, 17, 18, 19, 20) capable of receiving at least one medical device, said at least one guide means guiding the medical device towards said working area on the corresponding bone surface, each guide means defining a working axis (131, 141, 151, 161, 171, 181, 191) for moving the medical device along said working axis, said working area being determined by said working axes.
An apparatus comprising: an enclosure having first and second compartments (214, 216) having respective first and second opposing walls; a columnar cooling structure disposed between the first and second compartments (214, 216) and having a coolant passage defined therein configured to support a coolant flow in a direction parallel to the first and second opposing walls; a heatsink disposed in the coolant passage; and first and second semiconductor switches (230a, 230b) disposed in respective ones of the first and second compartments (214, 216) and thermally coupled to first and second sides of the heatsink so that both of the first and second semiconductor switches (230a, 230b) are cooled by the coolant flow through the heatsink, characterized in that the columnar cooling structure further comprises at least one vent (310a, 310b) on at least one of the first and second walls at a lower portion of the columnar cooling structure below the heatsink and configured to provide coolant from inside at least one of the first and second compartments to the coolant passage. an enclosure having first and second compartments (214, 216) having respective first and second opposing walls; a columnar cooling structure disposed between the first and second compartments (214, 216) and having a coolant passage defined therein configured to support a coolant flow in a direction parallel to the first and second opposing walls; a heatsink disposed in the coolant passage; and first and second semiconductor switches (230a, 230b) disposed in respective ones of the first and second compartments (214, 216) and thermally coupled to first and second sides of the heatsink so that both of the first and second semiconductor switches (230a, 230b) are cooled by the coolant flow through the heatsink, characterized in that the columnar cooling structure further comprises at least one vent (310a, 310b) on at least one of the first and second walls at a lower portion of the columnar cooling structure below the heatsink and configured to provide coolant from inside at least one of the first and second compartments to the coolant passage.