A surgical system, comprising: an outer shaft having a lumen extending therethrough; a suture anchor comprising a first anchor body having a distal portion, a proximal portion, and a first lumen extending longitudinally therethrough, and a second anchor body having a distal end mated to a proximal end of the first anchor body and having a second lumen extending therethrough that is configured to receive the proximal portion of the first anchor, the second anchor body having at least one opening extending through a side wall of the second anchor body at a position offset from proximal and distal ends (112p, 112d) thereof, wherein the proximal portion of the first anchor body has an external thread formed thereon that is configured to mate with a corresponding thread formed in the second lumen of the second anchor body; and an elongate inner shaft configured to be removably received within the lumen of the outer shaft and through the first and second anchor bodies (110, 112) such that a distal end of the inner shaft protrudes beyond a distal end of the distal portion, the inner shaft having a driver shaft portion configured to be removably coupled to the first anchor body within the first lumen such that the inner shaft is configured to be rotated to cause the proximal portion of the first anchor body to be threaded proximally into the second lumen and to occlude the opening of the second anchor body. an outer shaft having a lumen extending therethrough; a suture anchor comprising a first anchor body having a distal portion, a proximal portion, and a first lumen extending longitudinally therethrough, and a second anchor body having a distal end mated to a proximal end of the first anchor body and having a second lumen extending therethrough that is configured to receive the proximal portion of the first anchor, the second anchor body having at least one opening extending through a side wall of the second anchor body at a position offset from proximal and distal ends (112p, 112d) thereof, wherein the proximal portion of the first anchor body has an external thread formed thereon that is configured to mate with a corresponding thread formed in the second lumen of the second anchor body; and an elongate inner shaft configured to be removably received within the lumen of the outer shaft and through the first and second anchor bodies (110, 112) such that a distal end of the inner shaft protrudes beyond a distal end of the distal portion, the inner shaft having a driver shaft portion configured to be removably coupled to the first anchor body within the first lumen such that the inner shaft is configured to be rotated to cause the proximal portion of the first anchor body to be threaded proximally into the second lumen and to occlude the opening of the second anchor body. a first anchor body having a distal portion, a proximal portion, and a first lumen extending longitudinally therethrough, and a second anchor body having a distal end mated to a proximal end of the first anchor body and having a second lumen extending therethrough that is configured to receive the proximal portion of the first anchor, the second anchor body having at least one opening extending through a side wall of the second anchor body at a position offset from proximal and distal ends (112p, 112d) thereof, wherein the proximal portion of the first anchor body has an external thread formed thereon that is configured to mate with a corresponding thread formed in the second lumen of the second anchor body; and an elongate inner shaft configured to be removably received within the lumen of the outer shaft and through the first and second anchor bodies (110, 112) such that a distal end of the inner shaft protrudes beyond a distal end of the distal portion, the inner shaft having a driver shaft portion configured to be removably coupled to the first anchor body within the first lumen such that the inner shaft is configured to be rotated to cause the proximal portion of the first anchor body to be threaded proximally into the second lumen and to occlude the opening of the second anchor body.