mhurhangee/ep-ind-claims huggingface dataset:
Method for geographic region detection of traffic infrastructure by means of a receive unit disposed in the region of the traffic infrastructure for a detection region of the receive unit, wherein the method comprises the following steps: - Status data of a number of vehicles, which status data in each case includes at least a position of the respective vehicle and if necessary a time at which the position was determined, is communicated by the vehicles several times to the receive unit in the period during which the vehicles are passing through the detection region of the receive unit by means of wireless communication; wherein the method is characterised in that it comprises the following further steps: - The receive unit determines the first position received in the detection region and the last position received in the detection region for each vehicle from the transmitted status data; - The receive unit, or a processing unit connected to the receive unit, computes a vector for each vehicle, wherein the vector extends from the first position of the vehicle received in the detection region to the last position of the vehicle received in the detection region; - From the vectors of all vehicles the receive unit or processing unit determines directions of travel of the vehicles as well as the geographic location of roadways and/or lanes of the roadways of the traffic infrastructure in the detection region. - Status data of a number of vehicles, which status data in each case includes at least a position of the respective vehicle and if necessary a time at which the position was determined, is communicated by the vehicles several times to the receive unit in the period during which the vehicles are passing through the detection region of the receive unit by means of wireless communication; - The receive unit determines the first position received in the detection region and the last position received in the detection region for each vehicle from the transmitted status data; - The receive unit, or a processing unit connected to the receive unit, computes a vector for each vehicle, wherein the vector extends from the first position of the vehicle received in the detection region to the last position of the vehicle received in the detection region; - From the vectors of all vehicles the receive unit or processing unit determines directions of travel of the vehicles as well as the geographic location of roadways and/or lanes of the roadways of the traffic infrastructure in the detection region.
A pressure measuring assembly with a pressure measuring cell disposed in a process connection, wherein the process connection for accommodating the pressure measuring cell and coupling the same to a process environment is provided with a fastening portion and an accommodating portion with an accommodating space for at least one base body of the pressure measuring cell, wherein the process connection, at least in a portion adjacent to the process environment, is made from ceramic and comprises at least one ceramic diaphragm sealing the accommodating space from the process environment, characterized in that the pressure measuring cell has its own measuring diaphragm, which is connected to the ceramic diaphragm.
Use of a compound of formula: in which R and R', which may be the same or different, are H or C 1-5 alkyl, and R" is H or C 1-4 alkyl, optionally, when R" is H, in the form of a salt thereof with a pharmaceutically acceptable organic or mineral base, in the manufacture of a pharmaceutical composition for treating hypertriglyceridemia, hypercholesterolemia, or hyperglycaemia. R and R', which may be the same or different, are H or C 1-5 alkyl, and R" is H or C 1-4 alkyl, optionally, when R" is H, in the form of a salt thereof with a pharmaceutically acceptable organic or mineral base, in the manufacture of a pharmaceutical composition for treating hypertriglyceridemia, hypercholesterolemia, or hyperglycaemia.
In vitro method for non-invasive embryo competence assessment, comprising the following steps: a) determining the number of nucleic acid-containing extracellular vesicles in samples of a plurality of culture media of the same type, which were used to culture embryos, b) identifying an embryo with a higher number of nucleic acid-containing EVs in its culture medium as having a limited probability for clinical pregnancy relative to an embryo with a lower number of nucleic acid-containing EVs in its culture medium, wherein the embryos cultured in the plurality of culture media are from the same female. a) determining the number of nucleic acid-containing extracellular vesicles in samples of a plurality of culture media of the same type, which were used to culture embryos, b) identifying an embryo with a higher number of nucleic acid-containing EVs in its culture medium as having a limited probability for clinical pregnancy relative to an embryo with a lower number of nucleic acid-containing EVs in its culture medium,
Process for hydrotreating a biomass oil diluted in a refinery stream of petroleum hydrocarbons in a catalytic bed reactor, wherein the catalytic bed reactor comprises sulphided catalytic beds consisting of (i) a first monometallic catalytic bed containing a group VIB metal oxide and (ii) one or more second bimetallic catalytic beds for hydrotreating the refinery stream, preferably configuring a first reaction zone for hydroconversion of triglycerides and/or fatty acids into corresponding n-paraffins, wherein the process comprises the steps of: a) diluting a volume of a biomass oil comprising more than 70% wt of one or more triglycerides and/or one or more fatty acids in a refinery stream of petroleum hydrocarbons with a distillation range between 140 and 500°C to obtain a feedstock containing between 1 and 75% wt of the biomass oil, preferably wherein said one or more triglycerides have ester groups derived from fatty acids having a C12-C18 carbon chain and/or said one or more fatty acids have a C12-C18 carbon chain; b) mixing a hydrogen stream with the feedstock to obtain a first reaction mixture, which is heated and injected in the first catalytic bed at a temperature of between 220 and 370°C causing it to react under a pressure of between 3 and 15 MPa; c) injecting upstream of a second catalytic bed a dilution stream comprising hydrogen to obtain a second reaction mixture, which is hydrotreated under conditions for hydrotreating petroleum hydrocarbons, such that gaseous products and a stream of liquid hydrocarbons are obtained; d) separating the gaseous products, recovering a stream of liquid hydrocarbons containing dissolved gases, purifying the stream to remove dissolved gases to obtain a hydrotreated liquid product. a) diluting a volume of a biomass oil comprising more than 70% wt of one or more triglycerides and/or one or more fatty acids in a refinery stream of petroleum hydrocarbons with a distillation range between 140 and 500°C to obtain a feedstock containing between 1 and 75% wt of the biomass oil, preferably wherein said one or more triglycerides have ester groups derived from fatty acids having a C12-C18 carbon chain and/or said one or more fatty acids have a C12-C18 carbon chain; b) mixing a hydrogen stream with the feedstock to obtain a first reaction mixture, which is heated and injected in the first catalytic bed at a temperature of between 220 and 370°C causing it to react under a pressure of between 3 and 15 MPa; c) injecting upstream of a second catalytic bed a dilution stream comprising hydrogen to obtain a second reaction mixture, which is hydrotreated under conditions for hydrotreating petroleum hydrocarbons, such that gaseous products and a stream of liquid hydrocarbons are obtained; d) separating the gaseous products, recovering a stream of liquid hydrocarbons containing dissolved gases, purifying the stream to remove dissolved gases to obtain a hydrotreated liquid product.
An apparatus for delivering therapeutic agent to an eye, wherein the apparatus comprises: (a) a body; (b) a cannula extending distally from the body, wherein the cannula defines a longitudinal axis and includes a needle guide defining an internal lumen that includes a straight proximal portion corresponding to the longitudinal axis and a curved distal portion; (c) a hollow needle, wherein the needle is slidably received in the internal lumen such that the needle is slidable relative to the cannula; and (d) an actuation assembly, wherein the actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle through the curved distal portion of the internal lumen along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula; characterised in that: the cannula is sized and configured to be insertable between a choroid and a sclera of a patient's eye, and the cannula has a generally rectangular cross-section. (a) a body; (b) a cannula extending distally from the body, wherein the cannula defines a longitudinal axis and includes a needle guide defining an internal lumen that includes a straight proximal portion corresponding to the longitudinal axis and a curved distal portion; (c) a hollow needle, wherein the needle is slidably received in the internal lumen such that the needle is slidable relative to the cannula; and (d) an actuation assembly, wherein the actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle through the curved distal portion of the internal lumen along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula; characterised in that: the cannula is sized and configured to be insertable between a choroid and a sclera of a patient's eye, and the cannula has a generally rectangular cross-section.
A compound of formula I where: Ar 1 is phenyl, pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl, or benzodioxyl, and is substituted with 1-3 substituents selected from cyano, halo, alkyl, fluoroalkyl, alkoxy, fluoroalkoxy, alkylthio, and alkylsulfonyl; Ar 2 is phenyl, pyridinyl, pyridazinyl, pyrimidinyl, or pyrazinyl, and is substituted with 0-3 substituents selected from cyano, halo, alkyl, fluoroalkyl, alkoxy, and fluoroalkoxy; Ar 3 is 5- or 6-membered monocyclic heteroaromatic ring system with 1-5 heteroatoms independently selected from nitrogen, oxygen, and sulfur; R 1 is cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, tetrahyrofuranyl, or tetrahydropyranyl, and is substituted with 0-2 substituents selected from cyano, alkyl, haloalkyl, hydroxyalkyl, alkoxyalkyl, ((R 2)(R 3)N)alkyl, hydroxy, alkoxy, (R 2)(R 3)N, (R 2)(R 3)NCO, and Ar 3; R 2 is hydrogen, alkyl, alkylcarbonyl, or alkylsulfonyl; R 3 is hydrogen or alkyl; or NR 2 R 3 taken together is selected from azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, and morpholinyl, and is substituted with 0-3 substituents selected from halo, alkyl, fluoroalkyl, alkoxy, and fluoroalkoxy; and X is hydrogen, fluoro, hydroxy, or alkoxy; or a pharmaceutically acceptable salt thereof. Ar 1 is phenyl, pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl, or benzodioxyl, and is substituted with 1-3 substituents selected from cyano, halo, alkyl, fluoroalkyl, alkoxy, fluoroalkoxy, alkylthio, and alkylsulfonyl; Ar 2 is phenyl, pyridinyl, pyridazinyl, pyrimidinyl, or pyrazinyl, and is substituted with 0-3 substituents selected from cyano, halo, alkyl, fluoroalkyl, alkoxy, and fluoroalkoxy; Ar 3 is 5- or 6-membered monocyclic heteroaromatic ring system with 1-5 heteroatoms independently selected from nitrogen, oxygen, and sulfur; R 1 is cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, tetrahyrofuranyl, or tetrahydropyranyl, and is substituted with 0-2 substituents selected from cyano, alkyl, haloalkyl, hydroxyalkyl, alkoxyalkyl, ((R 2)(R 3)N)alkyl, hydroxy, alkoxy, (R 2)(R 3)N, (R 2)(R 3)NCO, and Ar 3; R 2 is hydrogen, alkyl, alkylcarbonyl, or alkylsulfonyl; R 3 is hydrogen or alkyl; or NR 2 R 3 taken together is selected from azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, and morpholinyl, and is substituted with 0-3 substituents selected from halo, alkyl, fluoroalkyl, alkoxy, and fluoroalkoxy; and X is hydrogen, fluoro, hydroxy, or alkoxy; or a pharmaceutically acceptable salt thereof.
Method to purify a compound of formula as a single enantiomer or as a mixture of isomers, comprising: a. one or more washes of an aqueous solution of a compound of formula and wherein the aqueous solution comprises NaCl from 0% to 5% w/w, with an organic solvent S1; b. increase of the concentration of NaCl of the aqueous solution of a compound of formula as in point a. greater than 5% w/w; c. one or more extractions of the aqueous solution of a compound of formula as in point b. with an organic solvent S2, and d. concentration of the solution of a compound of formula in an organic solvent S2 to obtain a compound of formula, and wherein the solvent S1 is an organic solvent selected from a cyclic or acyclic ether or a non-polar aprotic solvent, and wherein the solvent S2 is an organic solvent selected from a polar aprotic solvent; a chlorinated solvent; an ester; or a linear or branched C 3 -C 7 ketone. a. one or more washes of an aqueous solution of a compound of formula and wherein the aqueous solution comprises NaCl from 0% to 5% w/w, with an organic solvent S1; b. increase of the concentration of NaCl of the aqueous solution of a compound of formula as in point a. greater than 5% w/w; c. one or more extractions of the aqueous solution of a compound of formula as in point b. with an organic solvent S2, and d. concentration of the solution of a compound of formula in an organic solvent S2 to obtain a compound of formula,
Method for suppressing stray light guided into the used beam path of the optical imaging by way of mounted and unmounted regions of optical elements, characterized in that the mechanical mount of the optical elements is split structurally into a region for oriented fixation of the optical element in a mount and into a region in the form of a free space overlaying the optical element, wherein the free space is filled with a transparent cement material for stray light suppression and the region serving for oriented fixation is limited to the regions which do not contribute to forwarding stray light.
A method for tempering glass sheets to a surface compressive stress of at least 150 MPa, in which method the quenching of the glass sheet is carried out when the glass sheet travels through the quenching section by blowing air jets on the upper and lower surfaces of the glass sheet with a blower, through blowing apertures (6, 7) in the blowing box and by means of air compressor pressure through pipe nozzles, characterised in that the quenching section comprises at least three successive quenching zones, and the average convective heat transfer coefficient jointly produced by the blowing and the compressed air jets on the upper and lower surfaces of the glass sheet is at least 750 W/m 2 /K in the first zone, at least 10% lower in the second zone than in the first, and at least equally high in the third zone as in the first, and these zone-specific differences in the heat transfer coefficient are implemented by changing the blowing pressures of the pipe nozzles.
A liner assembly suitable for use with a pipeline section having at least one junction with a lateral pipe, the liner assembly comprising: an outer tubular liner having an opening therein generally coinciding in position with each junction when the liner assembly is positioned within said pipeline section; an inner malleable inflatable bladder positioned longitudinally within said tubular liner, the liner assembly further comprising a retaining sleeve generally coinciding in position with each opening, said bladder being inhibited from over-expanding during positioning and inflation of the liner assembly within the pipeline section by said retaining sleeve. an outer tubular liner having an opening therein generally coinciding in position with each junction when the liner assembly is positioned within said pipeline section; an inner malleable inflatable bladder positioned longitudinally within said tubular liner, the liner assembly further comprising a retaining sleeve generally coinciding in position with each opening, said bladder being inhibited from over-expanding during positioning and inflation of the liner assembly within the pipeline section by said retaining sleeve.
Method for assisting a user of a hearing system, comprising the steps of a) receiving a request for assistance from said user by means of a request-receiving unit of said hearing system; and b) automatically carrying out an assistance function upon step a), wherein said assistance function assists said user in case that a failure of at least one component of said hearing system has occurred and/or in case that said user has carried out manipulations which lead to an inappropriate status of said hearing system or of at least one device (11,11',12,13) of said hearing system. a) receiving a request for assistance from said user by means of a request-receiving unit of said hearing system; and b) automatically carrying out an assistance function upon step a),
Liquid-crystalline medium having negative dielectric anisotropy based on a mixture of polar compounds, characterised in that it comprises at least one compound of the formula I, in which R 1, R 1* in each case, independently of one another, denote an alkyl radical having 1-6 C atoms, and a denotes 0 or 1, and additionally one or more compounds of the formulae IIA, IIB and/or IIC, in which R 2A, R 2B and R 2C in each case, independently of one another, denote H, an alkyl radical having up to 15 C atoms which is unsubstituted, monosubstituted by CN or CF 3 or at least monosubstituted by halogen, where, in addition, one or more CH 2 groups in these radicals may be replaced by -O-, -S-, -C≡C-, -CF 2 O-, -OCF 2 -, -OC-O- or -O-CO- in such a way that O atoms are not linked directly to one another, L 1-4 in each case, independently of one another, denote F or Cl, Z 2 and Z 2' in each case, independently of one another, denote a single bond, -CH 2 CH 2 -, -CH=CH-, -CF 2 O-, -OCF 2 -, -CH 2 O-, -OCH 2 -, -COO-, -OCO-, -C 2 F 4 -, -CF=CF-, -CH=CHCH 2 O-, p denotes 1 or 2, q denotes 0 or 1, and v denotes 1 to 6, where the medium comprises at least three compounds selected from the group of the compounds of the formulae I-1 to I-6, and which comprises CPY-n-Om, CPY-n-Om in which n and m in each case, independently of one another, denote 1, 2, 3, 4, 5 or 6. R 1, R 1* in each case, independently of one another, denote an alkyl radical having 1-6 C atoms, and a denotes 0 or 1, R 2A, R 2B and R 2C in each case, independently of one another, denote H, an alkyl radical having up to 15 C atoms which is unsubstituted, monosubstituted by CN or CF 3 or at least monosubstituted by halogen, where, in addition, one or more CH 2 groups in these radicals may be replaced by -O-, -S-, -C≡C-, -CF 2 O-, -OCF 2 -, -OC-O- or -O-CO- in such a way that O atoms are not linked directly to one another, L 1-4 in each case, independently of one another, denote F or Cl, Z 2 and Z 2' in each case, independently of one another, denote a single bond, -CH 2 CH 2 -, -CH=CH-, -CF 2 O-, -OCF 2 -, -CH 2 O-, -OCH 2 -, -COO-, -OCO-, -C 2 F 4 -, -CF=CF-, -CH=CHCH 2 O-, p denotes 1 or 2, q denotes 0 or 1, and v denotes 1 to 6, n and m in each case, independently of one another, denote 1, 2, 3, 4, 5 or 6.
A unitized build assembly for a gas turbine engine, the unitized build assembly comprising: an exhaust duct; a hot section (106, 206, 306) with a locking structure, wherein the hot section (106, 206, 306) comprises a combustor (112, 212) and a turbine section, the hot section (106, 206, 306) at least partially circumferentially surrounding the exhaust duct; and a compressor section (104, 204, 304) having an interface structure, wherein the compressor section (104, 204, 304) is proximal to the hot section (106, 206, 306) and the hot section (106, 206, 306) at least partially circumferentially surrounds at least part of the compressor section (104, 204, 304), wherein the locking structure is configured to engage the interface structure to limit movement of the hot section (106, 206, 306) relative to the compressor section (104, 204, 304); wherein the build assembly is manufactured using additive manufacturing techniques; and characterized by a plurality of removable support structures (122, 222) extending between the compressor section (104, 204, 304) and the hot section (106, 206, 306). an exhaust duct; a hot section (106, 206, 306) with a locking structure, wherein the hot section (106, 206, 306) comprises a combustor (112, 212) and a turbine section, the hot section (106, 206, 306) at least partially circumferentially surrounding the exhaust duct; and a compressor section (104, 204, 304) having an interface structure, wherein the compressor section (104, 204, 304) is proximal to the hot section (106, 206, 306) and the hot section (106, 206, 306) at least partially circumferentially surrounds at least part of the compressor section (104, 204, 304), wherein the locking structure is configured to engage the interface structure to limit movement of the hot section (106, 206, 306) relative to the compressor section (104, 204, 304); wherein the build assembly is manufactured using additive manufacturing techniques; and characterized by a plurality of removable support structures (122, 222) extending between the compressor section (104, 204, 304) and the hot section (106, 206, 306).
Surgical system for connecting body tissue, comprising a surgical instrument having two tool elements (14, 16'; 16"; 16"') movable relative to each other, each of which comprises a high-frequency electrode (28, 29), the high-frequency electrodes (28, 29), in an approach position of the tool elements (14, 16'; 16"; 16"'), defining a minimum distance from each other, lying opposite each other and facing each other; a shaft, at the distal end of which at least a first one of the tool elements is arranged or formed; and wherein a second tool element (16'; 16"; 16"') is adapted to be moved from an operating position, in which it is adapted for movement into the approach position, into a removal position and/or vice versa, a surface area of a perpendicular projection of the second tool element onto a projection plane extending perpendicularly to the shaft direction in the region of the second tool element being smaller in the removal position than in the operating position, characterized in that the instrument comprises a ring-shaped, closed cutting edge.