A signal interference avoidance method for a first network device (700; 900), the signal interference avoidance method comprising: transmitting first interference avoidance indication information to a second network device, when a self-interference occurs for a User Equipment, UE, connected concurrently to the first network device (700; 900) and the second network device (800; 1000), wherein the first interference avoidance indication information is used to enable the second network device (800; 1000) to communicate with the UE through a first time-domain resource and/or a first frequency-domain resource, wherein the first network device (700; 900) is one of a Long Term Evolution, LTE, base station and a New Radio, NR, base station, while the second network device (800; 1000) is the other one of the LTE base station and the NR base station, the signal interference avoidance method being characterized by the first interference avoidance indication information comprises: identification information about the UE, identification information about each cell where the UE is located, and resource indication information about frequency-domain resources for the UE in the cell; the resource indication information about frequency-domain resources is a bitmap, and each bit in the bitmap represents one Physical Resource Block, PRB; when the bit has a value of 1, it indicates that the PRB at a corresponding position is used by the first network device (700; 900) for the downlink transmission, and when the bit has a value of 0, it indicates that the PRB at the corresponding position is not used by the first network device (700; 900) for the downlink transmission. transmitting first interference avoidance indication information to a second network device, when a self-interference occurs for a User Equipment, UE, connected concurrently to the first network device (700; 900) and the second network device (800; 1000), wherein the first interference avoidance indication information is used to enable the second network device (800; 1000) to communicate with the UE through a first time-domain resource and/or a first frequency-domain resource, wherein the first network device (700; 900) is one of a Long Term Evolution, LTE, base station and a New Radio, NR, base station, while the second network device (800; 1000) is the other one of the LTE base station and the NR base station, the signal interference avoidance method being characterized by the first interference avoidance indication information comprises: identification information about the UE, identification information about each cell where the UE is located, and resource indication information about frequency-domain resources for the UE in the cell; the resource indication information about frequency-domain resources is a bitmap, and each bit in the bitmap represents one Physical Resource Block, PRB; when the bit has a value of 1, it indicates that the PRB at a corresponding position is used by the first network device (700; 900) for the downlink transmission, and when the bit has a value of 0, it indicates that the PRB at the corresponding position is not used by the first network device (700; 900) for the downlink transmission.