mhurhangee/ep-ind-claims huggingface dataset:
A computer-implemented method for identifying a mutation in a nucleic acid, the method comprising: sequencing nucleic acid to generate a plurality of sequence reads; assembling a contig from the reads; aligning the contig to a reference sequence to provide a contig-to-reference alignment, such that both a genomic position of the contig and any differences between the contig and the reference sequence are determined, wherein the differences include both positional and variant information; aligning the individual reads back to the contig in a local, contig-specific alignment to provide read-to-contig alignments such that both a position of the reads with respect to the contig and any differences between the reads and the contig are determined, wherein the differences include both positional and variant information; mapping the read-to-contig alignments to the reference sequence using the contig-to-reference specific alignment to provide positional information relative to the reference sequence for each read, as well as any differences between the reference sequence and the reads, wherein the differences between the reference sequence and the reads are determined by: combining the differences between the reads and the contig and the differences between the contig and the reference sequence for each read, wherein each of the differences is expressed in the same format; and identifying a mutation for each read based on the combined differences. sequencing nucleic acid to generate a plurality of sequence reads; assembling a contig from the reads; aligning the contig to a reference sequence to provide a contig-to-reference alignment, such that both a genomic position of the contig and any differences between the contig and the reference sequence are determined, wherein the differences include both positional and variant information; aligning the individual reads back to the contig in a local, contig-specific alignment to provide read-to-contig alignments such that both a position of the reads with respect to the contig and any differences between the reads and the contig are determined, wherein the differences include both positional and variant information; mapping the read-to-contig alignments to the reference sequence using the contig-to-reference specific alignment to provide positional information relative to the reference sequence for each read, as well as any differences between the reference sequence and the reads, wherein the differences between the reference sequence and the reads are determined by: combining the differences between the reads and the contig and the differences between the contig and the reference sequence for each read, wherein each of the differences is expressed in the same format; and identifying a mutation for each read based on the combined differences. combining the differences between the reads and the contig and the differences between the contig and the reference sequence for each read, wherein each of the differences is expressed in the same format; and identifying a mutation for each read based on the combined differences.
Tank for the transport of fuel, comprising: - at least a first container body defining at least a first containment volume of at least one work liquid, - at least a second container body defining at least a second containment volume of fuel and provided with at least one housing seat inside which said first container body is fitted in a removable manner; characterized by the fact that it comprises reinforcing means of said second container body provided with at least one reinforcing element (8, 9) positioned through inside said second containment volume and adapted to counteract the deformation of said second container body; and characterized by the fact that said reinforcing element (8, 9) is made in a single body piece with said second container body. - at least a first container body defining at least a first containment volume of at least one work liquid, - at least a second container body defining at least a second containment volume of fuel and provided with at least one housing seat inside which said first container body is fitted in a removable manner; characterized by the fact that it comprises reinforcing means of said second container body provided with at least one reinforcing element (8, 9) positioned through inside said second containment volume and adapted to counteract the deformation of said second container body; and characterized by the fact that said reinforcing element (8, 9) is made in a single body piece with said second container body.
Mobile home having a front mask which replaces the windscreen and front body parts of the manufacturer of the underlying vehicle, wherein the front mask by way of holding elements is fastened to a support structure for the drive motor and the front axle, characterized in that a frame structure is provided so as to be disposed behind and on the front mask and/or integrated in the front mask.
A composition containing an immunogenic cell preparation of killed Leptospira bacteria in an ethylenediaminetetraacetic acid solution, characterised in that the solution comprises 5 to 50 mmols of ethylenediaminetetraacetic acid per litre.
A method of manufacturing a seal for a pill dispenser having a body including a plurality of recesses formed in a surface of the body, each recess having an open mouth bounded by a surrounding portion of the body surface, the method comprising the step of providing a cover film and being characterised by the steps of: (a) adhering a liner film in face to face contact with the cover film; (b) kiss cutting the liner film to cut a plurality of liners in the liner film; and (c) kiss cutting the cover film to cut a corresponding number of covers in the cover film, each cover being cut in the cover film so as to be aligned with, and smaller than, a corresponding liner such that each of the covers remains adhered in face to face contact with the corresponding liner, and each of the liners remains adhered to the cover film about the entire periphery of the corresponding cover. (a) adhering a liner film in face to face contact with the cover film; (b) kiss cutting the liner film to cut a plurality of liners in the liner film; and (c) kiss cutting the cover film to cut a corresponding number of covers in the cover film, each cover being cut in the cover film so as to be aligned with, and smaller than, a corresponding liner such that each of the covers remains adhered in face to face contact with the corresponding liner, and each of the liners remains adhered to the cover film about the entire periphery of the corresponding cover.
A method for producing polyaspartic acid, comprising the following steps: (a) contacting a mixture of: (i) aspartic acid, (ii) 1 to 25 mol%, based on the amount of aspartic acid used in moles, of an acidic catalyst, and (iii) water in a reactor; (b) heating the mixture according to (a) under reflux cooling without distillative removal of water at a reaction temperature of 100 to 220°C up to a degree of conversion of the aspartic acid of at least 1%; (c) polycondensing the reaction mixture according to (b) with simultaneous distillative removal of water at 170 to 250°C; (d) hydrolyzing the polycondensates according to (c) with addition of a base; and (e) optionally acidifying the salts of polyaspartic acid obtained in (d). (a) contacting a mixture of: (i) aspartic acid, (ii) 1 to 25 mol%, based on the amount of aspartic acid used in moles, of an acidic catalyst, and (iii) water in a reactor; (i) aspartic acid, (ii) 1 to 25 mol%, based on the amount of aspartic acid used in moles, of an acidic catalyst, and (iii) water (b) heating the mixture according to (a) under reflux cooling without distillative removal of water at a reaction temperature of 100 to 220°C up to a degree of conversion of the aspartic acid of at least 1%; (c) polycondensing the reaction mixture according to (b) with simultaneous distillative removal of water at 170 to 250°C; (d) hydrolyzing the polycondensates according to (c) with addition of a base; and (e) optionally acidifying the salts of polyaspartic acid obtained in (d).
A device for sensing a neurological signal while stimulation therapy is being provided wherein the stimulation therapy involves application of a stimulation signal comprising a stimulation phase and a passive recharge phase, comprising: a sensing electrode (118, 120) configured to sense the neurological signal; a blanking switch (302, 304) comprising a distal end and a proximal end; an electrically conductive pathway connected between the sensing electrode and the distal end of the blanking switch; a sensing amplifier connected to the proximal end of the blanking switch and configured to amplify the neurological signal; a controller configured to maintain the blanking switch in a non-conducting state during at least a portion of the recharge phase and until the stimulation phase of the stimulation signal that follows the recharge phase has ended and to maintain the blanking switch in a conducting state during at least another portion of the recharge phase. a sensing electrode (118, 120) configured to sense the neurological signal; a blanking switch (302, 304) comprising a distal end and a proximal end; an electrically conductive pathway connected between the sensing electrode and the distal end of the blanking switch; a sensing amplifier connected to the proximal end of the blanking switch and configured to amplify the neurological signal; a controller configured to maintain the blanking switch in a non-conducting state during at least a portion of the recharge phase and until the stimulation phase of the stimulation signal that follows the recharge phase has ended and to maintain the blanking switch in a conducting state during at least another portion of the recharge phase.
A masking system for an airfoil having a leading edge, a trailing edge and convex and concave surfaces (14, 12) extending therebetween, the masking system comprising: a locator for positioning the masking system along the trailing edge of the airfoil, the locator having a positioning tab; a first mask comprising: a trailing edge portion having locator pins for cooperating with the positioning tab to position the first mask along the trailing edge of the airfoil; and a leading edge portion for extending around the leading edge of the airfoil from the convex surface to the concave surface to locate the first mask along the convex surface of the airfoil, the leading edge portion having a retainer process; and a second mask comprising: a retainer portion for cooperating with the retainer process to retain the second mask along the leading edge of the airfoil; and a flange portion for extending between the locator pins to locate the second mask along the concave surface of the airfoil. a locator for positioning the masking system along the trailing edge of the airfoil, the locator having a positioning tab; a first mask comprising: a trailing edge portion having locator pins for cooperating with the positioning tab to position the first mask along the trailing edge of the airfoil; and a leading edge portion for extending around the leading edge of the airfoil from the convex surface to the concave surface to locate the first mask along the convex surface of the airfoil, the leading edge portion having a retainer process; and a trailing edge portion having locator pins for cooperating with the positioning tab to position the first mask along the trailing edge of the airfoil; and a leading edge portion for extending around the leading edge of the airfoil from the convex surface to the concave surface to locate the first mask along the convex surface of the airfoil, the leading edge portion having a retainer process; and a second mask comprising: a retainer portion for cooperating with the retainer process to retain the second mask along the leading edge of the airfoil; and a flange portion for extending between the locator pins to locate the second mask along the concave surface of the airfoil. a retainer portion for cooperating with the retainer process to retain the second mask along the leading edge of the airfoil; and a flange portion for extending between the locator pins to locate the second mask along the concave surface of the airfoil.
A cell, comprising: an element portion (a) in which a first electrode layer serving as a tubular support body, a solid electrolyte layer and a second electrode layer are laminated in that order; the solid electrolyte layer containing an oxide as a primary component, the solid electrolyte layer having a thickness of 30 μm or less, the solid electrolyte layer having a region devoid of the second electrode layer, the oxide containing a rare earth element; and a first layer located in the region devoid of the second electrode layer, the first layer provided on the solid electrolyte layer, the first layer containing the oxide as a primary component with a content of the rare earth element, the content different from a content of the rare earth element in the solid electrolyte layer, the first layer having a higher strength than the solid electrolyte layer. an element portion (a) in which a first electrode layer serving as a tubular support body, a solid electrolyte layer and a second electrode layer are laminated in that order; the solid electrolyte layer containing an oxide as a primary component, the solid electrolyte layer having a thickness of 30 μm or less, the solid electrolyte layer having a region devoid of the second electrode layer, the oxide containing a rare earth element; and a first layer located in the region devoid of the second electrode layer, the first layer provided on the solid electrolyte layer, the first layer containing the oxide as a primary component with a content of the rare earth element, the content different from a content of the rare earth element in the solid electrolyte layer, the first layer having a higher strength than the solid electrolyte layer.
A skin cosmetic composition comprising the following components,,,, and: from 0.5 to 6% by mass of a linear saturated fatty acid having 12 to 22 carbon atoms, from 0.01 to 5% by mass of an organic base, from 0.01 to 1% by mass of an inorganic base, from 0.5 to 6% by mass of a linear saturated alcohol having 12 to 22 carbon atoms, from 0.1 to 20% by mass of an oil agent, and water, wherein a total amount of components and, [ +], is from 1 to 12% by mass; a mass ratio /[ +], which is a mass ratio of component to the total amount of components and, [ +], is from 0.2 to 0.7; a molar ratio /[ +], which is a molar ratio of component to a total amount of components and, [ +], is from 5 to 60 mol%; and a molar ratio [ +]/, which is a molar ratio of the total amount of components and,[+], to component, is from 10 to 80 mol%. from 0.5 to 6% by mass of a linear saturated fatty acid having 12 to 22 carbon atoms, from 0.01 to 5% by mass of an organic base, from 0.01 to 1% by mass of an inorganic base, from 0.5 to 6% by mass of a linear saturated alcohol having 12 to 22 carbon atoms, from 0.1 to 20% by mass of an oil agent, and water,
A pharmaceutical composition for use in the treatment of a viral upper respiratory infection or a lower respiratory infection comprising a blocker selected from the group consisting of a calcium channel blocker, and a pharmaceutical acceptable diluent or carrier, wherein the calcium channel blocker is verapamil.
A polyol component comprising • at least 35 % by weight of a polyol a1) having an hydroxyl value between 80 and 300 mg KOH/g of resin and a glass transition temperature Tg of from -10 to 75 0 C, the polyol a1) being selected from polyester polyols, (meth)acrylic polyols, polycarbonate polyols, polyether polyols, polyurethane polyols, and mixtures and hybrids thereof, wherein the polyol either: ∘ has a number averaged molecular weight Mn of from 600 to 2,500 Dalton, and a weight averaged molecular weight Mw of from 1,000 to less than 3,000 Dalton, or ∘ is a (meth)acrylic polyol having a number averaged molecular weight Mn of from 900 to 2,500 Dalton, and having a weight averaged molecular weight Mw of from 1,500 to 4,000 Dalton, and • between 0.1 and 10 % by weight of polyurea product a2) as rheological agent, wherein the weight averaged molecular weight (Mw) and number averaged molecular weight (Mn) of the polyol are determined according to ASTM D 3593 by Gel Permeation Chromatography using polystyrene standards, glass transition temperature and hydroxyl value are determined as disclosed in the description. • at least 35 % by weight of a polyol a1) having an hydroxyl value between 80 and 300 mg KOH/g of resin and a glass transition temperature Tg of from -10 to 75 0 C, the polyol a1) being selected from polyester polyols, (meth)acrylic polyols, polycarbonate polyols, polyether polyols, polyurethane polyols, and mixtures and hybrids thereof, wherein the polyol either: ∘ has a number averaged molecular weight Mn of from 600 to 2,500 Dalton, and a weight averaged molecular weight Mw of from 1,000 to less than 3,000 Dalton, or ∘ is a (meth)acrylic polyol having a number averaged molecular weight Mn of from 900 to 2,500 Dalton, and having a weight averaged molecular weight Mw of from 1,500 to 4,000 Dalton, and ∘ has a number averaged molecular weight Mn of from 600 to 2,500 Dalton, and a weight averaged molecular weight Mw of from 1,000 to less than 3,000 Dalton, or ∘ is a (meth)acrylic polyol having a number averaged molecular weight Mn of from 900 to 2,500 Dalton, and having a weight averaged molecular weight Mw of from 1,500 to 4,000 Dalton, and • between 0.1 and 10 % by weight of polyurea product a2) as rheological agent,
A method for producing an illumination component with at least one spacer arranged thereon, which spacer is being provided as a gap limiter, which method provides, that initially at least one elastic part is being produced as spacer by injection moulding of a first component, and subsequently after the at least partial solidification of the first component the illumination component is injected onto the at least one elastic part as a spacer by injection moulding of a second component onto the at least one part already produced by injection moulding of the first component or by partially overmoulding the at least one part already produced by injection moulding of the first component by injection moulding of the second component, wherein pre-mouldings provided to be the elastic parts are themselves already produced by multi-component injection moulding, wherein a part of the material provided for the illumination component is injected onto a part of the elastic part consisting of elastic material.
A combustion chamber of a gas turbine assembly, comprising: a casing (8; 108), defining a combustion volume (8a; 108a) therein; a heat shield (10; 110), which lines the inside of the casing (8; 108) and comprises a plurality of tiles (12, 12a, 12b; 112, 112a, 112b) of a refractory material; structural elements (15; 25) shaped so as to define housing seats of the tiles (12, 12a, 12b; 112, 112a, 112b) and withhold the tiles (12, 12a, 12b; 112, 112a, 112b) in the respective housing seats; wherein the structural elements (15; 25) comprise supporting elements for a group of first tiles (12a; 112a, 112b), each having a protecting plate which delimits a respective portion of the combustion volume (8a; 108a); wherein each supporting element comprises a base, fixed to the casing (8; 108), and a pair of elastic fastening elements, extending from the base opposite to each other and shaped so as to withhold portions of respective first tiles (12a; 112a, 112b) against the casing (8; 108); wherein the protecting plate of each supporting element is carried by at least one respective elastic fastening element and is arranged to cover the base; characterized by thermal protection elements, arranged so as to cover portions of the structural elements (15; 25) facing the inside of the casing (8; 108); wherein the thermal protection elements comprise heat insulating layers of heat insulating material, lining respective faces of respective protecting plates oriented towards the inside of the casing (8; 108). a casing (8; 108), defining a combustion volume (8a; 108a) therein; a heat shield (10; 110), which lines the inside of the casing (8; 108) and comprises a plurality of tiles (12, 12a, 12b; 112, 112a, 112b) of a refractory material; structural elements (15; 25) shaped so as to define housing seats of the tiles (12, 12a, 12b; 112, 112a, 112b) and withhold the tiles (12, 12a, 12b; 112, 112a, 112b) in the respective housing seats; wherein the structural elements (15; 25) comprise supporting elements for a group of first tiles (12a; 112a, 112b), each having a protecting plate which delimits a respective portion of the combustion volume (8a; 108a); wherein each supporting element comprises a base, fixed to the casing (8; 108), and a pair of elastic fastening elements, extending from the base opposite to each other and shaped so as to withhold portions of respective first tiles (12a; 112a, 112b) against the casing (8; 108); wherein the protecting plate of each supporting element is carried by at least one respective elastic fastening element and is arranged to cover the base; characterized by thermal protection elements, arranged so as to cover portions of the structural elements (15; 25) facing the inside of the casing (8; 108); wherein the thermal protection elements comprise heat insulating layers of heat insulating material, lining respective faces of respective protecting plates oriented towards the inside of the casing (8; 108).
A parison pressing plunger for a press-and-blow glassware manufacturing machine, which includes: a base, a nose, and a body extending between the base and the nose, said body having a central axis and an outer surface of revolution around the central axis, the outer surface of revolution including at least first and second spaced portions (40 and 42) and an intermediate third portion extending between the first and second spaced portions, the first and second spaced portions being conical and tapering in the direction from the base toward the nose at angles of not more than 2° to the axis and the third portion is a conical outer surface and tapering in the direction from the base toward the nose at an angle between 4° and 6° inclusive to the axis. a base, a nose, and a body extending between the base and the nose, said body having a central axis and an outer surface of revolution around the central axis, the outer surface of revolution including at least first and second spaced portions (40 and 42) and an intermediate third portion extending between the first and second spaced portions, the first and second spaced portions being conical and tapering in the direction from the base toward the nose at angles of not more than 2° to the axis and the third portion is a conical outer surface and tapering in the direction from the base toward the nose at an angle between 4° and 6° inclusive to the axis.