mhurhangee/ep-ind-claims huggingface dataset:
A single-stranded oligonucleotide, wherein all nucleosides of the oligonucleotide are 2'-O-alkyl ribose ribonucleosides, for use in the treatment of the human or animal body, wherein said oligonucleotide is capable of making a change in the sequence of a target RNA molecule present in a living cell of said human or animal body, by providing the oligonucleotide to the living cell under conditions allowing uptake by the living cell of said oligonucleotide, wherein said oligonucleotide comprises a sequence that is at least partially complementary to the target RNA molecule, such that hybridization of the oligonucleotide to the target RNA, or a precursor thereof, or a template therefor, takes place in said living cell, allowing biochemical machinery present in said living cell to copy a difference in sequence of the oligonucleotide relative to the target RNA molecule onto the RNA molecule, either directly or via a precursor thereof or a template there for, so as to bring about the change in said target RNA.
A sensor system comprising a sensor and a mast on which the sensor is mounted, the mast comprising a core body and a plurality of shrouds, whereby each shroud is provided about the core body and is independently rotatable with respect to the core body under the influence, in use, of a fluid flow flowing past the plurality of shrouds, and where further each shroud is shaped so that, from at least one fluid flow direction, each shroud presents a different flow resistance in dependence upon its rotational orientation, such that the rotational orientation of each shroud adjusts to reduce the flow resistance produced by the shroud to the fluid flow in response to the commencement of, or a change in the fluid flow direction to, one of the at least one fluid flow directions.
A hearing aid comprising a battery connected to supply power to a hearing aid circuit with an input transducer configured to output an audio signal based on a signal applied to the input transducer and representing sound, a hearing loss processor configured to compensate a hearing loss of a user of the hearing aid and output a hearing loss compensated audio signal, an output transducer configured to output an auditory output signal based on the hearing loss compensated audio signal that can be received by the human auditory system resulting in the user hearing sound, and a wireless communication unit configured to communicate wirelessly with another device, at least one capacitor, and a current limiting unit, characterized in that the at least one capacitor is coupled to supply peak currents to the wireless communication unit, and the at least one capacitor is further connected to the battery through the current limiting unit for replenishment of the at least one capacitor with energy from the battery, whereby the at least one capacitor draws lower peak currents from the battery than if the current limiting unit was absent.
An upsetting device comprising a top die and a bottom die that can be fastened to a forging press, in such a way that said dies (1, 2) can move in a vertical direction between an open position and a closed position, such that in the closed position the distance between the dies (1, 2) is less than in the open position, the device comprising at least two upsetting elements, wherein the position of the at least two upsetting elements according to a longitudinal direction perpendicular to the vertical direction is different in the open and closed positions, characterized in that each die (1, 2) comprises at least an inclined surface with respect to the vertical direction, each upsetting element has a complementary inclined surface that is in contact with the inclined surface of one of the dies (1, 2), both in the open position and in the closed position, said at least two upsetting elements being arranged opposite one another such that in at least any position other than the open position they are in contact by non-inclined surfaces opposite the complementary inclined surfaces.
An acoustic sensor comprising: an optical waveguide configured to emit an optical beam; a substantially planar first substrate optically coupled to the optical waveguide, the first substrate configured to be illuminated by the optical beam and to reflect at least a portion of the optical beam to the optical waveguide, the first substrate comprising: a first substrate portion configured to reflect a first portion of the optical beam back to the optical waveguide; and a diaphragm configured to reflect a second portion of the optical beam back to the optical waveguide, the diaphragm responsive to a perturbation by moving relative to the first substrate portion, the optical beam centered on a region between the first substrate portion and the diaphragm; and a substantially planar second substrate affixed to the first substrate and affixed to the optical waveguide, the second substrate substantially parallel to the first substrate, characterized in that the second substrate comprises a feedthrough hole extending through the second substrate and configured to receive the optical waveguide. an optical waveguide configured to emit an optical beam; a substantially planar first substrate optically coupled to the optical waveguide, the first substrate configured to be illuminated by the optical beam and to reflect at least a portion of the optical beam to the optical waveguide, the first substrate comprising: a first substrate portion configured to reflect a first portion of the optical beam back to the optical waveguide; and a diaphragm configured to reflect a second portion of the optical beam back to the optical waveguide, the diaphragm responsive to a perturbation by moving relative to the first substrate portion, the optical beam centered on a region between the first substrate portion and the diaphragm; and a substantially planar second substrate affixed to the first substrate and affixed to the optical waveguide, the second substrate substantially parallel to the first substrate, a first substrate portion configured to reflect a first portion of the optical beam back to the optical waveguide; and a diaphragm configured to reflect a second portion of the optical beam back to the optical waveguide, the diaphragm responsive to a perturbation by moving relative to the first substrate portion, the optical beam centered on a region between the first substrate portion and the diaphragm; and a substantially planar second substrate affixed to the first substrate and affixed to the optical waveguide, the second substrate substantially parallel to the first substrate, characterized in that the second substrate comprises a feedthrough hole extending through the second substrate and configured to receive the optical waveguide.
A motor vehicle headlamp having an assembly comprising a first semiconductor light source, a second semiconductor light source, a first concave mirror reflector, a second concave mirror reflector, a third semiconductor light source and a third concave mirror reflector, wherein each semiconductor light source is composed of at least two separate semiconductor chips (16.1, 16.2, 36.i, 38.j, 24.1, 24.2), characterised in that the second semiconductor light source is composed of a first group of semiconductor chips and a second group of of semiconductor chips, and having a control circuit configured for operating, when the headlamp is switched on, either the first semiconductor light source without the third semiconductor light source, or the third semiconductor light source without the first semiconductor light source, and to operate exclusively the first group of semiconductor chips of the second semiconductor light source together with the first semiconductor light source, and to operate at least the second group of semiconductor chips of the second semiconductor light source together with the third semiconductor light source.
A device for extracting an ingredient in a cartridge by supplying an extraction liquid such as heated water into such cartridge, comprising: - upstream and downstream cartridge enclosing parts (7, 8) relatively movable between an open position for inserting and/or removing such cartridge and a closed position for forming an extraction chamber enclosing such cartridge during extraction; and - at least one piercer selected from an upst ream piercer borne by the upstream part for opening an upst ream portion of such cartridge and a downstream piercer borne by the downstream part for opening a downstream portion of such cartridge, said at least one piercer (30,34) has a generally tapered shape, in particular a tapered shape that has a truncation surface delimiting a piercing edge, characterised in that said at least one tapered piercer has a base with a reinforcing foot extending transversally away from said tapered shape, in particular a foot having a body (34") extending around an entire periphery of the base and/or a body (34"') extending radially or diameterally or diagonally from the base. - upstream and downstream cartridge enclosing parts (7, 8) relatively movable between an open position for inserting and/or removing such cartridge and a closed position for forming an extraction chamber enclosing such cartridge during extraction; and - at least one piercer selected from an upst ream piercer borne by the upstream part for opening an upst ream portion of such cartridge and a downstream piercer borne by the downstream part for opening a downstream portion of such cartridge,
A method of preparing a disordered crystalline composition having a water solubility of greater than 0.3% (w/w) comprising: (i) heating a mixture comprising water and a composition comprising rebaudioside M and rebaudioside D to a temperature between 120°C and 130°C, (ii) maintaining the mixture at the temperature in (i) for between 5 minutes to 1 hour to provide a concentrated solution, (iii) decreasing the temperature to greater than 95°C, and (iv) spray-drying the concentrated solution while maintaining the feed temperature about 95°C. (i) heating a mixture comprising water and a composition comprising rebaudioside M and rebaudioside D to a temperature between 120°C and 130°C, (ii) maintaining the mixture at the temperature in (i) for between 5 minutes to 1 hour to provide a concentrated solution, (iii) decreasing the temperature to greater than 95°C, and (iv) spray-drying the concentrated solution while maintaining the feed temperature about 95°C.
A protective helmet comprising a chin guard removable from an operating position, for protecting the chin, characterized in that the shell of said helmet is provided with a portion for coupling with said chin guard when removed.
A method for decoding a video signal using a graph-based transform which is obtained by a graph representing relationship information between pixels in a block, wherein the relationship information between pixels is defined based on a graph edge corresponding to a line connecting pixels and an edge weight corresponding to an intensity of the statistical dependence between the pixels, the method comprising: receiving a template index for a coding block from the video signal, wherein the template index indicates a graph-based transform template to be applied to the coding block; deriving a graph-based transform matrix for the coding block corresponding to the template index; and decoding the coding block based on the graph-based transform matrix, wherein the template index corresponds to one template graph in a predetermined template graph set, wherein the predetermined template graph set includes a plurality of template graphs, and wherein the plurality of template graphs have a pattern in which a corner region in the coding block has a smaller edge weight than other regions in the coding block. receiving a template index for a coding block from the video signal, wherein the template index indicates a graph-based transform template to be applied to the coding block; deriving a graph-based transform matrix for the coding block corresponding to the template index; and decoding the coding block based on the graph-based transform matrix, wherein the template index corresponds to one template graph in a predetermined template graph set, wherein the predetermined template graph set includes a plurality of template graphs, and wherein the plurality of template graphs have a pattern in which a corner region in the coding block has a smaller edge weight than other regions in the coding block.
A method for three-dimensional beamforming, the method comprising: estimating a channel spatial coherence for a beam space of a terminal device based on a plurality of non-precoded reference signals, the beam space comprising a plurality of beam subspaces, each of the plurality of beam subspaces including a beam direction representative of a respective beam subspace of the plurality of beam subspaces; selecting, by the terminal device, a beam subspace of the plurality of beam subspaces based on a channel quality metric of the beam direction that is representative of the beam subspace; defining the plurality of beam subspaces based on the estimated channel spatial coherence; and performing a bounding procedure on the plurality of beam subspaces that may be selected by the terminal device. estimating a channel spatial coherence for a beam space of a terminal device based on a plurality of non-precoded reference signals, the beam space comprising a plurality of beam subspaces, each of the plurality of beam subspaces including a beam direction representative of a respective beam subspace of the plurality of beam subspaces; selecting, by the terminal device, a beam subspace of the plurality of beam subspaces based on a channel quality metric of the beam direction that is representative of the beam subspace; defining the plurality of beam subspaces based on the estimated channel spatial coherence; and performing a bounding procedure on the plurality of beam subspaces that may be selected by the terminal device.
A drug delivery system, comprising a supporting structure including at least one pharmaceutically acceptable carrier or excipient; a therapeutic composition including zotarolimus or a salt thereof and paclitaxel or a salt thereof, wherein zotarolimus or a salt thereof and paclitaxel or a salt thereof are present in ratio, r, of zotarolimus:paclitaxel that is 10:7≤ r ≤ 10:0.1; and wherein the system is to be implanted in a lumen of a blood vessel of a subject and is capable of reducing neointimal hyperplasia after being implanted in the lumen when compared to a control system.
A method for automatically recommissioning a lighting node using wireless signal characteristics, the method comprising: receiving, at each lighting node of a plurality of lighting nodes, a plurality of respective wireless signals from the other lighting nodes of the plurality of lighting nodes; determining, for each lighting node of the plurality of lighting nodes, received signal strength indicators, RSSIs, for each of the plurality of respective wireless signals received from the other lighting nodes; generating, for each lighting node of the plurality of lighting nodes, an RSSI fingerprint based on the RSSIs of the respective wireless signals received from the other lighting nodes and storing the thus generated RSSI fingerprints; determining a respective lighting node role for each lighting node of the plurality of lighting nodes; storing associations between the RSSI fingerprints and the lighting node roles; identifying a new lighting node that has been used to replace an out-of-service lighting node of the plurality of lighting nodes; receiving, at the new lighting node, a plurality of respective wireless signals from the remaining lighting nodes of the plurality of lighting nodes; generating a new RSSI fingerprint for the new lighting node based on the plurality of respective wireless signals from the remaining lighting nodes; determining, based on the stored RSSI fingerprints and the new RSSI fingerprint, that the new lighting node is a replacement for the out-of-service lighting node; and assigning the lighting node role previously assigned to the out-of-service lighting node to the new lighting node. receiving, at each lighting node of a plurality of lighting nodes, a plurality of respective wireless signals from the other lighting nodes of the plurality of lighting nodes; determining, for each lighting node of the plurality of lighting nodes, received signal strength indicators, RSSIs, for each of the plurality of respective wireless signals received from the other lighting nodes; generating, for each lighting node of the plurality of lighting nodes, an RSSI fingerprint based on the RSSIs of the respective wireless signals received from the other lighting nodes and storing the thus generated RSSI fingerprints; determining a respective lighting node role for each lighting node of the plurality of lighting nodes; storing associations between the RSSI fingerprints and the lighting node roles; identifying a new lighting node that has been used to replace an out-of-service lighting node of the plurality of lighting nodes; receiving, at the new lighting node, a plurality of respective wireless signals from the remaining lighting nodes of the plurality of lighting nodes; generating a new RSSI fingerprint for the new lighting node based on the plurality of respective wireless signals from the remaining lighting nodes; determining, based on the stored RSSI fingerprints and the new RSSI fingerprint, that the new lighting node is a replacement for the out-of-service lighting node; and assigning the lighting node role previously assigned to the out-of-service lighting node to the new lighting node.
Wire cutting device for cutting unfired bricks, comprising a wire for cutting said unfired bricks, tensioning means for keeping said wire tensioned between two ends, wherein the cutting device comprises two wire holders (4, 6) for holding the wire between said ends, away from a straight line between said ends and at an intermediate distance from each other, and damping means for resiliently mounting said wire holders (4, 6) on the cutting device, comprises displacement means (12, 13) for moving the wire downwards through a horizontal unfired brick and comprises control means for controlling said movement, characterized in that the cutting device comprises a fixing element for retaining at least a part of a brick to be cut when cutting the latter.
A machining tool (12, 50) comprising a recess formed at the periphery of the machining tool (12, 50) and a cutting insert positioning system being disposed within the recess, the cutting insert positioning system comprising a cartridge for positioning a cutting insert on the machining tool (12, 50), the cutting insert being configured to be clamped onto the cartridge, said cartridge having a central longitudinal axis, along which the cutting insert is configured to be positioned, wherein the cutting insert positioning system comprises a wedge for displacing the cartridge along the central longitudinal axis, the cartridge comprising: - an end wall contacting the wedge and supporting the cartridge, said end wall defining a first surface extending beyond the end wall and transversally to the central longitudinal axis, - a rear wall for supporting the cartridge against the machining tool (12, 50) and defining a second surface extending beyond the rear wall, - a front clamping wall having a clamping hole, said clamping hole extending along a clamping direction and being configured to receive a clamping screw for clamping the cartridge onto the machining tool, characterized in that the clamping direction is arranged to intersect the first and second surfaces of the cartridge. - an end wall contacting the wedge and supporting the cartridge, said end wall defining a first surface extending beyond the end wall and transversally to the central longitudinal axis, - a rear wall for supporting the cartridge against the machining tool (12, 50) and defining a second surface extending beyond the rear wall, - a front clamping wall having a clamping hole, said clamping hole extending along a clamping direction and being configured to receive a clamping screw for clamping the cartridge onto the machining tool,
Process for manufacturing a hollow body comprising a thermoplastic wall and a fibrous reinforcement welded on at least one portion of the outer surface of said wall, the fibrous reinforcement comprising a thermoplastic similar to or compatible with that of the wall of the hollow body, having a thickness of at least 1 mm and comprising from 30 to 60% in weight of fibres, according to which: - the portion of the outer surface of the hollow body where the reinforcement will be welded is heated; - the fibrous reinforcement is also heated so as to soften or even preferably melt the thermoplastic of the reinforcement; and - the reinforcement is moved to and applied to said portion of the outer surface of the hollow body, characterised in that the step of applying the reinforcement to said portion of the outer surface of the hollow body comprises: - applying an initial pressure on at least one portion of the reinforcement; - applying pressure for the final welding using robotized pressure applying means. - the portion of the outer surface of the hollow body where the reinforcement will be welded is heated; - the fibrous reinforcement is also heated so as to soften or even preferably melt the thermoplastic of the reinforcement; and - the reinforcement is moved to and applied to said portion of the outer surface of the hollow body, - applying an initial pressure on at least one portion of the reinforcement; - applying pressure for the final welding using robotized pressure applying means.
A belt retractor for a vehicle seat belt, comprising a frame, a belt reel which is rotatably supported within the frame, a blocking mechanism adapted to react at least sensitive to webbing and including a locking disk, and a child-proof locking mechanism controlled by a planetary gearing, characterized in that a sensor tranquilizing mechanism (84, 88, 90) which is equally controlled by the planetary gearing is provided.
An apparatus of a high-efficiency, HE, access point, AP, the apparatus comprising: memory; and, processing circuitry coupled to the memory, wherein the processing circuitry configured to: encode a multi-user, MU, block acknowledgement request, BAR,MU-BAR,, the MU-BAR to indicate to a plurality of HE stations, STAs, to simultaneously transmit block acknowledgements, BAs, to the HE AP, the MU-BAR to indicate which subchannel each HE STA of the plurality of HE STAs should use to transmit a BA to the HE AP; configure the HE AP to transmit the MU-BAR; and receive the BAs from the plurality of HE STAs. encode a multi-user, MU, block acknowledgement request, BAR,MU-BAR,, the MU-BAR to indicate to a plurality of HE stations, STAs, to simultaneously transmit block acknowledgements, BAs, to the HE AP, the MU-BAR to indicate which subchannel each HE STA of the plurality of HE STAs should use to transmit a BA to the HE AP; configure the HE AP to transmit the MU-BAR; and receive the BAs from the plurality of HE STAs.
A turbine stage for a turbine engine, the stage comprising a stationary nozzle and a wheel mounted downstream from the nozzle and inside an annular casing, the nozzle being attached to the casing and being retained axially downstream by bearing against an annular split ring mounted in an annular groove of a rail of the casing, the wheel being mounted inside a sectorized ring carried by the casing, each ring sector including at its upstream end a member of C-shaped section that is engaged on the casing rail and that holds the split ring radially in the above-mentioned groove, the stage being characterized in that the radially inner wall of the C-shaped member of each ring sector extends inside the split ring over the entire axial dimension thereof and its upstream end portion is engaged in at least one recess (160, 162) of the nozzle, the upstream circumferential edge of the radially inner wall of the C-shaped member of each ring sector including at least one notch (180, 182) cooperating with complementary means (164, 166) of the nozzle in order to prevent a ring sector from moving in rotation relative to the nozzle.