mhurhangee/ep-ind-claims huggingface dataset:
A Long Term Evolution/Evolved Packet Core (LTE/EPC) communication network comprising: a Policy and Charging Rules Function, PCRF, operable to store charging rules for a user; and a plurality of LTE network elements operable to transmit requests for charging rules to the PCRF for a session involving the user, to receive the charging rules from the PCRF, to generate charging messages for the session, and to transmit the charging messages to a charging system; the network being characterized by: the requests for the charging rules from the LTE network elements including at least one network/access charging identifier; the PCRF being further operable to assign an LTE charging identifier for the session by associating the network/access charging identifiers received in the requests, and to transmit the LTE charging identifier to the LTE network elements along with the charging rules; and the LTE network elements being further operable to insert the LTE charging identifier in the charging messages to the charging system. a Policy and Charging Rules Function, PCRF, operable to store charging rules for a user; and a plurality of LTE network elements operable to transmit requests for charging rules to the PCRF for a session involving the user, to receive the charging rules from the PCRF, to generate charging messages for the session, and to transmit the charging messages to a charging system; the requests for the charging rules from the LTE network elements including at least one network/access charging identifier; the PCRF being further operable to assign an LTE charging identifier for the session by associating the network/access charging identifiers received in the requests, and to transmit the LTE charging identifier to the LTE network elements along with the charging rules; and the LTE network elements being further operable to insert the LTE charging identifier in the charging messages to the charging system.
A soluble PD1-41BBL fusion protein for use in the treatment of cancer, wherein the fusion protein is in a form of a homo-trimer, comprises SEQ ID NO: 1 and is capable of: (i) binding PD-L1 and 41BB; (ii) activating said 41BB signaling pathway in a cell expressing said 41BB; and (iii) co-stimulating immune cells expressing said 41BB. (i) binding PD-L1 and 41BB; (ii) activating said 41BB signaling pathway in a cell expressing said 41BB; and (iii) co-stimulating immune cells expressing said 41BB.
Bypass device for accepting chyme from the stomach and for bypass-type conducting of the chyme through the pylorus in or through the duodenum of a patient, comprising a tubular, radially collapsible and self-erecting transpyloric conducting element (4, 7), which penetrates the pylorus, having a central conducting lumen for the chyme, and fixing elements for anchoring the transpyloric conducting element (4, 7) on the pylorus, consisting of an annular gastric anchor element, which is arranged on the gastric side or proximal to the pylorus, for anchoring the transpyloric conducting element (4, 7) proximally to the pylorus, having a gastric balloon segment, which regionally delimits a cavity of annular structure fillable with a medium, and also an annular duodenal anchor element, which is located on the intestine side or distally to the pylorus in the duodenum, for anchoring the transpyloric conducting element (4, 7) distally to the pylorus, having a duodenal balloon segment, which regionally delimits a cavity of annular structure fillable with a medium, characterized in that the gastric balloon segment and/or the duodenal balloon segment encloses the radial exterior of the transpyloric conducting segment (4, 7), is not closed along a circumferential line in the toroidal direction, and is connected to the conducting element (4, 7) such that the latter forms a part of the enclosure of the relevant toroidal cavity, wherein the conducting element (4, 7) is formed or reinforced at least in its region encompassing the gastric and/or duodenal cavity such that it has a higher structural stability or self-erection capability there than the relevant balloon segment (6, 8) in the immediate surroundings, and wherein at least one balloon segment (6, 8) has a free edge area extending circumferentially, which is closed in a ring shape and presses against the transpyloric conducting element (4, 7), which free edge area (i) is everted such that it presses flatly with its inner side, which faces the regarding cavity, against the transpyloric conducting segment (4, 7), and (ii) is connected to the transpyloric conducting element (4, 7) to form a seal.
An in vitro method for determining the prognosis for survival of a patient with colorectal cancer and regional lymph node metastases comprising: a. Contacting a suspension comprising peripheral blood mononuclear cells (PMBCs) and cancer patient serum with lipopolysaccharide; b. Measuring the amount of interleukin 6 (IL-6) in the suspension from (a); and c. Classifying said patient as having a reduced prognosis for survival when the amount of IL-6 in the suspension of (a) is above the amount of IL-6 in a suspension of lipopolysaccharide, and PBMCs and serum proteins from a human with colorectal cancer and a good prognosis; or d. Classifying said patient as having an increased prognosis for survival when the amount of IL-6 in the suspension of (a) is equivalent to the amount of IL-6 in a suspension of lipopolysaccharide, and PBMCs and serum proteins from a human with colorectal cancer and a good prognosis. a. Contacting a suspension comprising peripheral blood mononuclear cells (PMBCs) and cancer patient serum with lipopolysaccharide; b. Measuring the amount of interleukin 6 (IL-6) in the suspension from (a); and c. Classifying said patient as having a reduced prognosis for survival when the amount of IL-6 in the suspension of (a) is above the amount of IL-6 in a suspension of lipopolysaccharide, and PBMCs and serum proteins from a human with colorectal cancer and a good prognosis; or d. Classifying said patient as having an increased prognosis for survival when the amount of IL-6 in the suspension of (a) is equivalent to the amount of IL-6 in a suspension of lipopolysaccharide, and PBMCs and serum proteins from a human with colorectal cancer and a good prognosis.
A machine-implemented method for controlling retry of unicast data packet transmission from a transmitter node to a receiver node, the method comprising steps of: selecting said receiver node from a set of receiver nodes having different processing delays; transmitting a first unicast data packet to said receiver node; receiving, at said transmitter node, an acknowledgement packet from said receiver node after an actual acknowledgement duration; responsive to the actual acknowledgement wait duration being less than an expected acknowledgement wait duration, setting said expected acknowledgement wait duration to a new expected acknowledgement wait duration comprising at least said actual acknowledgement wait duration; transmitting a second unicast data packet to said receiver node; setting a retry count threshold; responsive to no receipt of an acknowledgement of the second packet within said new expected acknowledgement wait duration, retrying the step of transmitting the second unicast data packet; responsive to a crossing of said retry count threshold, resetting said new expected acknowledgement wait duration to said expected acknowledgement wait duration. selecting said receiver node from a set of receiver nodes having different processing delays; transmitting a first unicast data packet to said receiver node; receiving, at said transmitter node, an acknowledgement packet from said receiver node after an actual acknowledgement duration; responsive to the actual acknowledgement wait duration being less than an expected acknowledgement wait duration, setting said expected acknowledgement wait duration to a new expected acknowledgement wait duration comprising at least said actual acknowledgement wait duration; transmitting a second unicast data packet to said receiver node; setting a retry count threshold; responsive to no receipt of an acknowledgement of the second packet within said new expected acknowledgement wait duration, retrying the step of transmitting the second unicast data packet; responsive to a crossing of said retry count threshold, resetting said new expected acknowledgement wait duration to said expected acknowledgement wait duration.
A peptide having an overall length of between 10 and 14 amino acids comprising a sequence selected from the group of a) a sequence consisting of SEQ ID No. 1 b) a variant of SEQ ID No. 1 that induces T cells cross-reacting with said peptide, wherein said variant is selected from the group of the sequences LFQILQGIVF, LYQILQGIVL, LYQILQGIVI, LFQILQGIVL, and LFQILQGIVI. a) a sequence consisting of SEQ ID No. 1 b) a variant of SEQ ID No. 1 that induces T cells cross-reacting with said peptide, wherein said variant is selected from the group of the sequences LFQILQGIVF, LYQILQGIVL, LYQILQGIVI, LFQILQGIVL, and LFQILQGIVI.
An information processing apparatus, comprising: a camera for picking up a live image; a display unit; an inputting apparatus interface configured to receive user input from an inputting apparatus; a picked up image displaying unit configured to live display the picked up live image on the display unit, the picked up live image being an image of a space in which a face of one or more users exist, a registered user information retaining block for retaining information including face identification data as registered user information in an associated relationship with a user account; and a face authentication unit configured to determine that a face of a registered user is included in the picked up live image on the display unit using the face identification data retained in the registered user information retaining unit, characterized by an image processing unit configured to display a position designation image on the display unit at a location below the determined face of the registered user; an object authentication unit configured to detect that an image of the inputting apparatus is included in a designated region designated by the position designation image, of the picked up live image; and a login processing unit configured to allow, when the object authentication unit detects that the image of the inputting apparatus is included in the designated region, the registered user to log in. a camera for picking up a live image; a display unit; an inputting apparatus interface configured to receive user input from an inputting apparatus; a picked up image displaying unit configured to live display the picked up live image on the display unit, the picked up live image being an image of a space in which a face of one or more users exist, a registered user information retaining block for retaining information including face identification data as registered user information in an associated relationship with a user account; and a face authentication unit configured to determine that a face of a registered user is included in the picked up live image on the display unit using the face identification data retained in the registered user information retaining unit, characterized by an image processing unit configured to display a position designation image on the display unit at a location below the determined face of the registered user; an object authentication unit configured to detect that an image of the inputting apparatus is included in a designated region designated by the position designation image, of the picked up live image; and a login processing unit configured to allow, when the object authentication unit detects that the image of the inputting apparatus is included in the designated region, the registered user to log in.
A method for reconstructing a tomographic image from projection data representing a number of detected photons, comprising: scaling a regularization term of an update algorithm of an iterative reconstruction algorithm with regularization with a scaling value, wherein the scaling value is variable in at least one spatial dimension, thereby varying the regularization of the iterative reconstruction in the least one dimension, wherein the scaling value varies the regularization such that in regions of the image where a total or average number of detected photons is higher the regularization strength is stronger and in regions of the image where the number of detected photons is lower the regularization strength is less strong, and wherein the update algorithm includes a constant regularization term; wherein the scaling includes multiplying the constant regularization term by the scaling value at each update; and iteratively reconstructing an image based at least on the update algorithm, the varying scaled regularization term, and projection data. scaling a regularization term of an update algorithm of an iterative reconstruction algorithm with regularization with a scaling value, wherein the scaling value is variable in at least one spatial dimension, thereby varying the regularization of the iterative reconstruction in the least one dimension, wherein the scaling value varies the regularization such that in regions of the image where a total or average number of detected photons is higher the regularization strength is stronger and in regions of the image where the number of detected photons is lower the regularization strength is less strong, and wherein the update algorithm includes a constant regularization term; wherein the scaling includes multiplying the constant regularization term by the scaling value at each update; and iteratively reconstructing an image based at least on the update algorithm, the varying scaled regularization term, and projection data.
Device for the attachment and the adjustment of a bearing in an orifice provided for that purpose in a bridge or a plate of a timepiece, comprising: - A first screw, said bearing screw, defining a support opening of such a bearing having a diameter d1, said first screw comprising an external thread having an external diameter df1 larger than d1 and a length L1, measured perpendicularly to said diameters d1, df1; - A second screw, said locking screw, defining an internal bore of diameter d2 smaller or equal to d1, said second screw comprising an external thread having an external diameter df2 larger than diameters d2, d1, df1 and a length L2, measured perpendicularly to said diameters d2, df2; and - A socket defining a tubular housing extending following a longitudinal axis (A-A'), said tubular housing comprising a first tapped section, adapted to screw the first screw, and a second tapped section, adapted to screw the second screw, said tapped sections being joined by a medium section of linear guiding of said screws (2, 3); - The external threads (F1, F2) of the first and second screws (2, 3) and the corresponding sections (S1, S2) of the socket have respective screwing pitches in opposite directions. - A first screw, said bearing screw, defining a support opening of such a bearing having a diameter d1, said first screw comprising an external thread having an external diameter df1 larger than d1 and a length L1, measured perpendicularly to said diameters d1, df1; - A second screw, said locking screw, defining an internal bore of diameter d2 smaller or equal to d1, said second screw comprising an external thread having an external diameter df2 larger than diameters d2, d1, df1 and a length L2, measured perpendicularly to said diameters d2, df2; and - A socket defining a tubular housing extending following a longitudinal axis (A-A'), said tubular housing comprising a first tapped section, adapted to screw the first screw, and a second tapped section, adapted to screw the second screw, said tapped sections being joined by a medium section of linear guiding of said screws (2, 3); - The external threads (F1, F2) of the first and second screws (2, 3) and the corresponding sections (S1, S2) of the socket have respective screwing pitches in opposite directions.
An apparatus for limiting a current of a circuit or breaking a current, comprising: a current breaking branch, the current breaking branch comprising one breaking unit or at least two breaking units that are connected in series, each breaking unit comprising one solid-state direct current circuit breaker and one non-linear resistance connected in parallel, further comprising a bridge branch, the bridge branch comprising two bridge arms formed by four identical current commutation branches (A, B, C, D), wherein every two of the four current commutation branches are connected in series, the formed two bridge arms are then connected in parallel, the two bridge arms are both connected in parallel to the current breaking branch, and middle points (3, 4) of the two bridge arms are separately connected to two ends of a circuit, characterized in that each current commutation branch comprises at least one high-speed isolation switch and at least one bidirectional power semiconductor switch that are connected in series; and a direction in which a current enters from the middle point of a first bridge arm and sequentially flows through a first current commutation branch in the first bridge arm, the current breaking branch, and a fourth current commutation branch in a second bridge arm is defined as a first current direction, a direction in which a current enters from the middle point of the second bridge arm and sequentially flows through a third current commutation branch in the second bridge arm, the current breaking branch, and a second current commutation branch in the first bridge arm is defined as a second current direction, and an arrangement direction of the solid-state DC circuit breaker is the same as the first and second current directions.
A vehicle ventilation module (102, 103, 105) comprising: a return air duct having a return air inlet fluidly connected to a return air outlet downstream of the return air inlet; a fresh air duct (214, 202) having a fresh air inlet fluidly connected to a fresh air outlet downstream of the fresh air inlet; a heat exchanger thermally coupled to the return air duct and the fresh air duct (214, 202), wherein the heat exchanger is upstream of the return air outlet and the fresh air outlet, and downstream of the return air inlet and the fresh air inlet; characterized in comprising: a first door joining an upstream portion of the return air duct upstream of the heat exchanger and an upstream portion of the fresh air duct (214, 202) upstream of the heat exchanger; and a second door joining a downstream portion of the return air duct downstream of the heat exchanger and a downstream portion of the fresh air duct (214, 202) downstream of the heat exchanger; wherein the first door and the second door are operable to selectively open and close to allow air downstream and/or upstream of the heat exchanger to pass between the fresh air duct (214, 202) and the return air duct, wherein the return air outlet is configured to be coupled with a HVAC system of a vehicle to provide air to the HVAC system. a return air duct having a return air inlet fluidly connected to a return air outlet downstream of the return air inlet; a fresh air duct (214, 202) having a fresh air inlet fluidly connected to a fresh air outlet downstream of the fresh air inlet; a heat exchanger thermally coupled to the return air duct and the fresh air duct (214, 202), wherein the heat exchanger is upstream of the return air outlet and the fresh air outlet, and downstream of the return air inlet and the fresh air inlet; characterized in comprising: a first door joining an upstream portion of the return air duct upstream of the heat exchanger and an upstream portion of the fresh air duct (214, 202) upstream of the heat exchanger; and a second door joining a downstream portion of the return air duct downstream of the heat exchanger and a downstream portion of the fresh air duct (214, 202) downstream of the heat exchanger; a first door joining an upstream portion of the return air duct upstream of the heat exchanger and an upstream portion of the fresh air duct (214, 202) upstream of the heat exchanger; and a second door joining a downstream portion of the return air duct downstream of the heat exchanger and a downstream portion of the fresh air duct (214, 202) downstream of the heat exchanger; wherein the first door and the second door are operable to selectively open and close to allow air downstream and/or upstream of the heat exchanger to pass between the fresh air duct (214, 202) and the return air duct, wherein the return air outlet is configured to be coupled with a HVAC system of a vehicle to provide air to the HVAC system.
A surgical system for use in a surgical procedure, the surgical system comprising: at least one imaging device; and a control circuit configured to: identify an anatomical organ targeted by the surgical procedure; generate a virtual three-dimensional construct of at least a portion of the anatomical organ based on visualization data from the at least one imaging device; identify anatomical structures relevant to the surgical procedure from the visualization data from the at least one imaging device; couple the anatomical structures to the virtual 3D construct; and overlay onto the virtual 3D construct a layout plan of the surgical procedure determined based on the anatomical structures. at least one imaging device; and a control circuit configured to: identify an anatomical organ targeted by the surgical procedure; generate a virtual three-dimensional construct of at least a portion of the anatomical organ based on visualization data from the at least one imaging device; identify anatomical structures relevant to the surgical procedure from the visualization data from the at least one imaging device; couple the anatomical structures to the virtual 3D construct; and overlay onto the virtual 3D construct a layout plan of the surgical procedure determined based on the anatomical structures. identify an anatomical organ targeted by the surgical procedure; generate a virtual three-dimensional construct of at least a portion of the anatomical organ based on visualization data from the at least one imaging device; identify anatomical structures relevant to the surgical procedure from the visualization data from the at least one imaging device; couple the anatomical structures to the virtual 3D construct; and overlay onto the virtual 3D construct a layout plan of the surgical procedure determined based on the anatomical structures.
A method for producing cancer stem cells, comprising: a) transducing cancer cells with a vector expressing Δ133p53β isoform, Δ133p53γ isoform, or both Δ133p53β and Δ133p53γ isoforms; b) culturing transduced cancer cells in a medium supporting expansion of transduced cancer cells; and c) isolating cancer stem cells by means of at least one of the 4 following methods: i) isolation according to CSC-specific cell surface markers; ii) isolation by flow cytometry based on side-population phenotype by DNA dye exclusion; iii) isolation by flow cytometry based on high aldehyde dehydrogenase (ALDH) activity; and iv) submission to sphere-forming assay and collection of spheres. a) transducing cancer cells with a vector expressing Δ133p53β isoform, Δ133p53γ isoform, or both Δ133p53β and Δ133p53γ isoforms; b) culturing transduced cancer cells in a medium supporting expansion of transduced cancer cells; and c) isolating cancer stem cells by means of at least one of the 4 following methods: i) isolation according to CSC-specific cell surface markers; ii) isolation by flow cytometry based on side-population phenotype by DNA dye exclusion; iii) isolation by flow cytometry based on high aldehyde dehydrogenase (ALDH) activity; and iv) submission to sphere-forming assay and collection of spheres. i) isolation according to CSC-specific cell surface markers; ii) isolation by flow cytometry based on side-population phenotype by DNA dye exclusion; iii) isolation by flow cytometry based on high aldehyde dehydrogenase (ALDH) activity; and iv) submission to sphere-forming assay and collection of spheres.