mhurhangee/ep-ind-claims huggingface dataset:
A machine-implemented method for adapting a storage subsystem, included in an operating system executing on a processing device, to a non-volatile block storage device (141, 142), the machine-implemented method comprising: monitoring, by the non-volatile block storage device (141, 142), operations from the processing device; maintaining statistics with respect to I/O patterns of the processing device, said I/O patterns including read patterns and write patterns; determining, if a minimum number of operations from the processing device has been observed, whether a threshold has been reached or crossed; and if the threshold has been reached or crossed, providing feedback to the storage subsystem said feedback indicating a predefined profile comprising an associated I/O pattern for subsequent use of the non-volatile block storage device (141, 142). monitoring, by the non-volatile block storage device (141, 142), operations from the processing device; maintaining statistics with respect to I/O patterns of the processing device, said I/O patterns including read patterns and write patterns; determining, if a minimum number of operations from the processing device has been observed, whether a threshold has been reached or crossed; and if the threshold has been reached or crossed, providing feedback to the storage subsystem said feedback indicating a predefined profile comprising an associated I/O pattern for subsequent use of the non-volatile block storage device (141, 142).
A method for cutting or machining of internal gear teeth on a workpiece which is rotatable about its rotation axis and radially delimits a free space that extends axially to one side beyond the internally toothed region and whose radial extension is tapered along the direction of its axial extension in at least one point, wherein, to carry out said method, an externally toothed tool which is rotationally driven about its rotation axis is brought from the opposite side into rolling engagement with the internally toothed region, forming an axis intersection angle, characterised in that the chips which are produced and subjected to centrifugal force are caused to change their movement through the application of a mechanical force in the area upstream from the tapering point in a manner directed against the origin of the centrifugal force, wherein the application of the mechanical force occurs as a result of the chips colliding with a non-corotating collision partner (30, 36) of greater mass.
A method of making a composite gas separation module, wherein said method comprises: providing a porous support having a metal membrane layer thereon with a surface; imposing onto said surface and said metal membrane layer a surface morphology with a maximum peak height (Sp) and a maximum pit height (Sv) in the range of from 0.5 to 10μm that provides for an activated surface having enhanced activation properties for the placement thereon of a subsequent metal membrane layer; placing said subsequent metal membrane layer upon said activated surface without the application of a chemical activation solution; and annealing said subsequent metal membrane layer to provide an annealed metal layer. providing a porous support having a metal membrane layer thereon with a surface; imposing onto said surface and said metal membrane layer a surface morphology with a maximum peak height (Sp) and a maximum pit height (Sv) in the range of from 0.5 to 10μm that provides for an activated surface having enhanced activation properties for the placement thereon of a subsequent metal membrane layer; placing said subsequent metal membrane layer upon said activated surface without the application of a chemical activation solution; and annealing said subsequent metal membrane layer to provide an annealed metal layer.
A compound according to Formula I: or a pharmaceutically acceptable salt thereof, wherein: Base is a nucleobase; X is O or S; V is hydrogen, halogen or amino; Z 1 is halogen; Z 2 is halogen; R 1 and R 2 together with the two oxygen atoms to which they are attached form the ring: R 9 is C 1-10 alkyl, C 3-10 cycloalkyl, aryl or arylC 1-6 alkyl; R 10 is C 1-10 alkyl or COOR 9; R 11 is C 1-10 alkylcarbonyloxyC 1-10 alkyl, C 3-10 cycloalkylcarbonyoxy, aryl, aryloxy, C 1-10 alkylaryl, arylC 1-10 alkyl, heteroaryl, heteroarylC 1-10 alkyl or C 1-10 alkylheteroaryl; R z is C 2-11 alkenyl, C 2-11 alkynyl, C 1-10 alkoxycarbonylC 1-10 alkyl, C 1-10 alkylcarbonylthioC 1-10 alkyl, C 1-10 alkyldisulfideC 1-6 alkyl, aryl or heteroarylC 1-10 alkyl, wherein alkyl is optionally substituted by one, two or three substituents independently selected from halogen and hydroxy, and heteroaryl is substituted by one or two substituents selected from C 1-10 alkyl and nitro; and W is O or S. Base is a nucleobase; X is O or S; V is hydrogen, halogen or amino; Z 1 is halogen; Z 2 is halogen; R 1 and R 2 together with the two oxygen atoms to which they are attached form the ring: R 9 is C 1-10 alkyl, C 3-10 cycloalkyl, aryl or arylC 1-6 alkyl; R 10 is C 1-10 alkyl or COOR 9; R 11 is C 1-10 alkylcarbonyloxyC 1-10 alkyl, C 3-10 cycloalkylcarbonyoxy, aryl, aryloxy, C 1-10 alkylaryl, arylC 1-10 alkyl, heteroaryl, heteroarylC 1-10 alkyl or C 1-10 alkylheteroaryl; R z is C 2-11 alkenyl, C 2-11 alkynyl, C 1-10 alkoxycarbonylC 1-10 alkyl, C 1-10 alkylcarbonylthioC 1-10 alkyl, C 1-10 alkyldisulfideC 1-6 alkyl, aryl or heteroarylC 1-10 alkyl, wherein alkyl is optionally substituted by one, two or three substituents independently selected from halogen and hydroxy, and heteroaryl is substituted by one or two substituents selected from C 1-10 alkyl and nitro; and W is O or S.
A chain conveyor (1; 101), in particular for food products, comprising two ring chains having each a respective plurality of rings (4, 5) connected to one another; a plurality of support bars, each of which extends between the two ring chains and is connected to corresponding rings (4, 5) of the ring chains; a driving gear wheel, which is mounted so as to rotate around a rotation axis and feed the ring chains along a given path; and a plurality of wings (6; 106; 106'), each of which is engaged with a respective ring chain so as to form a respective side edge; wherein the support bars define a support surface for at least one product to be transported, and wherein each ring chain comprises a plurality of first rings, which are substantially parallel to the support surface, and a plurality of second rings, which are alternated with the first rings and are substantially perpendicular to the support surface; and wherein each wing (6; 106; 106') is mounted in a releasable manner on a single respective bar and on a single respective ring (4,5); characterized in that each wing (6; 106; 106') comprises a containment wall, which is transverse to the surface and is substantially parallel to the path; a sliding block, which is mounted so as to slide on a respective guide extending along the path; and a coupling element (19; 19'), which is interposed between the containment wall and the sliding block; wherein each coupling element (19; 19') comprises a tubular body having an axis that is transverse to the guide and parallel to said surface; wherein the tubular body has a cavity, which is suited to house a bar and a radial opening, which establishes a connection between said cavity and an external area; wherein the tubular body is fitted around a respective bar; in particular, the opening faces the outside in a direction that is opposite to the feeding direction; wherein the coupling element (19; 19') comprises, furthermore, an appendage, which axially projects from the tubular body towards the respective ring chain; wherein the appendage comprises, in turn, an abutment having contact faces, which are arranged in contact with a respective ring (4,5); in particular, the abutment leans against the respective ring (4,5).
A method of forming a negative electrode for a lithium secondary battery, the method comprising: forming a first mixture by mixing silicon nanoparticles having an average particle diameter (D 50) of 70 nm to 300 nm, a first conductive material, a first cellulose-based compound having a weight average molecular weight of 10,000 Da to 500,000 Da, and a solvent; forming a second mixture by mixing a graphite-based active material having an average particle diameter (D 50) of 5 μm to 50 μm, a second cellulose-based compound having a weight average molecular weight of 1,000,000 Da to 2,500,000 Da, and a solvent; forming a negative electrode active material slurry by mixing the first mixture and the second mixture; and forming a negative electrode active material layer by applying the negative electrode active material slurry on a negative electrode current collector, the average particle diameter being measured using a laser diffraction method or a scanning electrode microscope image and being defined as a particle diameter at 50% in cumulative particle diameter distribution based on a volume, the weight average molecular weight meaning a polystyrene reduced weight average molecular weight measured by gel permeation chromatography. forming a first mixture by mixing silicon nanoparticles having an average particle diameter (D 50) of 70 nm to 300 nm, a first conductive material, a first cellulose-based compound having a weight average molecular weight of 10,000 Da to 500,000 Da, and a solvent; forming a second mixture by mixing a graphite-based active material having an average particle diameter (D 50) of 5 μm to 50 μm, a second cellulose-based compound having a weight average molecular weight of 1,000,000 Da to 2,500,000 Da, and a solvent; forming a negative electrode active material slurry by mixing the first mixture and the second mixture; and forming a negative electrode active material layer by applying the negative electrode active material slurry on a negative electrode current collector, the average particle diameter being measured using a laser diffraction method or a scanning electrode microscope image and being defined as a particle diameter at 50% in cumulative particle diameter distribution based on a volume, the weight average molecular weight meaning a polystyrene reduced weight average molecular weight measured by gel permeation chromatography.
An edible composition, which is an oil-in-water (O/W) emulsion comprising from 30 to 38wt.% water and ≤30 wt.% total fat, and has a water activity (a w) at 20°C of ≥0.80.
V-type 4-stroke internal combustion engine having 20 cylinders, having a counter-clockwise or clockwise direction of rotation, comprising a crankshaft, characterized in that the engine further comprises a torsional vibration damper and a flywheel arranged on the crankshaft, wherein the crankshaft has 10 crank throws forming a crank star, wherein in each case the piston rods of the two cylinders of a V-segment are connected to the same crank throw, wherein the crank throws C1 to C10 have one of the following angular sequences in the direction of rotation of the engine when seen from the side of the flywheel, with the crank throws numbered as C1 to C10 when starting from the side of the flywheel: i) C1, C9, C4, C6, C3, C10, C2, C7, C5, C8 ii) C1, C8, C5, C7, C2, C10, C3, C6, C4, C9 iii) C1, C9, C5, C7, C3, C10, C2, C6, C4, C8 iv) C1, C9, C7, C3, C6, C10, C2, C4, C8, C5 v) C1, C7, C5, C8, C2, C10, C4, C6, C3, C9 vi) C1, C9, C7, C3, C5, C10, C2, C4, C8, C6 vii) C1, C6, C8, C4, C2, C10, C5, C3, C7, C9 viii) C1, C5, C8, C4, C2, C10, C6, C3, C7, C9 ix) C1, C8, C4, C6, C2, C10, C3, C7, C5, C9. i) C1, C9, C4, C6, C3, C10, C2, C7, C5, C8 ii) C1, C8, C5, C7, C2, C10, C3, C6, C4, C9 iii) C1, C9, C5, C7, C3, C10, C2, C6, C4, C8 iv) C1, C9, C7, C3, C6, C10, C2, C4, C8, C5 v) C1, C7, C5, C8, C2, C10, C4, C6, C3, C9 vi) C1, C9, C7, C3, C5, C10, C2, C4, C8, C6 vii) C1, C6, C8, C4, C2, C10, C5, C3, C7, C9 viii) C1, C5, C8, C4, C2, C10, C6, C3, C7, C9 ix) C1, C8, C4, C6, C2, C10, C3, C7, C5, C9.
Towing apparatus, comprising: a towing vehicle, particularly a tractor, and a trailer device for attaching to the towing vehicle by way of a tow bar, the towing vehicle comprising: a towing mechanism, in particular a hitch, into which the tow bar of the trailer device can be clipped so as to be pivotable around a first pivot point, and a lower link arm, particularly a height-adjustable lower link arm, arranged at the rear of the towing vehicle, the lower link arm being set up such that, when the tow bar is attached to the towing mechanism, the lower link arm brings about an interlock of the first pivot point while the trailer device is being towed, and the lower link arm being able to be brought into engagement with the tow bar by adjusting its height, so as to interlock the first pivot point, characterized in that a second pivot point arranged at the rear in relation to the first pivot point in a forward direction of travel is provided on the tow bar. a towing vehicle, particularly a tractor, and a trailer device for attaching to the towing vehicle by way of a tow bar, the towing vehicle comprising: a towing mechanism, in particular a hitch, into which the tow bar of the trailer device can be clipped so as to be pivotable around a first pivot point, and a lower link arm, particularly a height-adjustable lower link arm, arranged at the rear of the towing vehicle, the lower link arm being set up such that, when the tow bar is attached to the towing mechanism, the lower link arm brings about an interlock of the first pivot point while the trailer device is being towed, and the lower link arm being able to be brought into engagement with the tow bar by adjusting its height, so as to interlock the first pivot point, characterized in that a second pivot point arranged at the rear in relation to the first pivot point in a forward direction of travel is provided on the tow bar. a towing mechanism, in particular a hitch, into which the tow bar of the trailer device can be clipped so as to be pivotable around a first pivot point, and a lower link arm, particularly a height-adjustable lower link arm, arranged at the rear of the towing vehicle, the lower link arm being set up such that, when the tow bar is attached to the towing mechanism, the lower link arm brings about an interlock of the first pivot point while the trailer device is being towed, and the lower link arm being able to be brought into engagement with the tow bar by adjusting its height, so as to interlock the first pivot point, characterized in that a second pivot point arranged at the rear in relation to the first pivot point in a forward direction of travel is provided on the tow bar.
Actuator having a planetary roller screw drive, the actuator having a housing with a cylinder chamber and a pressure medium reservoir, the pressure medium reservoir and the cylinder chamber forming a common volume, and the housing being filled with a pressure medium fluid, and the planetary roller screw drive having a spindle with a profiling (26.1) which meshes with a plurality of planetary rollers which are arranged around the spindle in an axially parallel manner with respect to the spindle and in each case have a profiling and are mounted at the two ends in a planetary roller carrier, the planetary rollers meshing with an inner profiling of an internal gear which surrounds them, and the planetary roller carriers being supported in a sleeve which surrounds the internal gear, characterized in that the planetary roller carriers and/or the sleeve have/has one or more flow ducts (38.1) which connect the inner space and the outer space of the space which is delimited radially by the sleeve and axially by the planetary roller carriers to one another.
An excavator comprising: an undercarriage; an slewing upper structure rotatably mounted on the undercarriage; attachments, mounted on the slewing upper structure, and including a boom, an arm, and an end attachment; a boom cylinder configured to drive the boom; a first hydraulic mechanism section configured to operate according to an operation of the attachments; a second hydraulic mechanism section, provided in an oil passage between a bottom-side oil chamber of the boom cylinder and the first hydraulic mechanism section, and configured to close when a lowering operation of the boom is not performed; and a control device, characterized in that: the control device releases a closed state of the second hydraulic mechanism section according to whether or not an unstable action of the excavator is generated, and controls a released state so that an acting velocity in a lowering direction of the boom is less than or equal to a predetermined reference. an undercarriage; an slewing upper structure rotatably mounted on the undercarriage; attachments, mounted on the slewing upper structure, and including a boom, an arm, and an end attachment; a boom cylinder configured to drive the boom; a first hydraulic mechanism section configured to operate according to an operation of the attachments; a second hydraulic mechanism section, provided in an oil passage between a bottom-side oil chamber of the boom cylinder and the first hydraulic mechanism section, and configured to close when a lowering operation of the boom is not performed; and a control device, characterized in that: the control device releases a closed state of the second hydraulic mechanism section according to whether or not an unstable action of the excavator is generated, and controls a released state so that an acting velocity in a lowering direction of the boom is less than or equal to a predetermined reference.
A safety device for a pre-filled syringe comprising - a hollow support body (1.2) for mounting the pre-filled syringe therein, - a hollow needle shield (1.1) that is slidable relative to the support body (1.2), - and guiding means for guiding the movement of the needle shield (1.1) relative to the support body (1.2), wherein the guiding means comprise - a flexible arm (1.1.4) with a guide pin (1.1.3) extending from the flexible arm (1.1.4) in a radial direction, - a guide track (1.2.5), wherein the guide pin (1.1.3) protrudes into the guide track (1.2.5) and - a separating wall (1.2.6) that extends into the guide track (1.2.5) in a direction parallel to a central axis of the safety device and wherein, when the needle shield (1.1) is slid relative to the support body (1.2), the guide pin (1.1.3) moves along the guide track (1.2.5) and the movement of the guide pin (1.1.3) along the guide track (1.2.5) is guided by the interplay of the flexible arm (1.1.4) and the separating wall (1.2.6), characterized in that, when the needle shield (1.1) is slid relative to the support body (1.2), the guide pin (1.1.3) moves along the guide track (1.2.5) to deflect the flexible arm (1.1.4) in a lateral direction perpendicular to the central axis and that the safety device comprises means (1.2.1, 1.2.2) for preventing relative rotation between the support body (1.2) and the needle shield (1.1). - a hollow support body (1.2) for mounting the pre-filled syringe therein, - a hollow needle shield (1.1) that is slidable relative to the support body (1.2), - and guiding means for guiding the movement of the needle shield (1.1) relative to the support body (1.2), wherein the guiding means comprise - a flexible arm (1.1.4) with a guide pin (1.1.3) extending from the flexible arm (1.1.4) in a radial direction, - a guide track (1.2.5), wherein the guide pin (1.1.3) protrudes into the guide track (1.2.5) and - a separating wall (1.2.6) that extends into the guide track (1.2.5) in a direction parallel to a central axis of the safety device and - a flexible arm (1.1.4) with a guide pin (1.1.3) extending from the flexible arm (1.1.4) in a radial direction, - a guide track (1.2.5), wherein the guide pin (1.1.3) protrudes into the guide track (1.2.5) and - a separating wall (1.2.6) that extends into the guide track (1.2.5) in a direction parallel to a central axis of the safety device and
An isolated nucleic acid encoding a polypeptide, the polypeptide comprising a zinc finger peptide having from 8 to 32 zinc finger domains and which binds to CAG- and/or CTG-trinucleotide repeat nucleic acid sequences; wherein the zinc finger peptide comprising the sequence: N'- [(Formula 4) - L 3] n0 - {[(Formula 6) - L 2 - (Formula 6) - L 3] n1 - [(Formula 6) - L 2 - (Formula 6) - X L]} n2 - [(Formula 4) - L 2 - (Formula 6) - L3] n3 - [(Formula 6) - L 2 - (Formula 6)] - [L 3 - (Formula 6) -] n4 -C', wherein n0 is 0 or 1, n1 is from 1 to 4, n2 is 1 or 2, n3 is from 1 to 4, n4 is 0 or 1, L 2 is the linker sequence -TG E / Q K / R P- (SEQ ID NO: 7), L 3 is the linker sequence -TG G / S E / Q K / R P- (SEQ ID NO: 8), and X L is a linker sequence of between 8 and 50 amino acids; Formula 4 is a zinc finger domain of the sequence X 2 C X 2,4 C X 5 X -1 X +1 X +2 X +3 X +4 X +5 X +6 H X 3,4,5 H / C and Formula 6 is a zinc finger domain of the sequence X 2 C X 2 C X 5 X -1 X +1 X +2 X +3 X +4 X +5 X +6 H X 3 H, wherein X is any amino acid, the numbers in subscript indicate the possible numbers of residues represented by X at that position, and the number in superscript indicates the position of the amino acid in the recognition sequence of the zinc finger domain; and wherein at least 8 adjacent zinc finger domains have a recognition sequence X -1 X +1 X +2 X +3 X +4 X +5 X +6 according to SEQ ID NO: 1; wherein the sequence of SEQ ID NO: 1 is selected from a combination of SEQ ID NOs: 2 and 5; from a combination of SEQ ID NOs: 3 and 4; from a combination of SEQ ID NOs: 2, 3 or 4, or from a combination of SEQ ID NOs: 3, 4 and 5. N'- [(Formula 4) - L 3] n0 - {[(Formula 6) - L 2 - (Formula 6) - L 3] n1 - [(Formula 6) - L 2 - (Formula 6) - X L]} n2 - [(Formula 4) - L 2 - (Formula 6) - L3] n3 - [(Formula 6) - L 2 - (Formula 6)] - [L 3 - (Formula 6) -] n4 -C', wherein n0 is 0 or 1, n1 is from 1 to 4, n2 is 1 or 2, n3 is from 1 to 4, n4 is 0 or 1, L 2 is the linker sequence -TG E / Q K / R P- (SEQ ID NO: 7), L 3 is the linker sequence -TG G / S E / Q K / R P- (SEQ ID NO: 8), and X L is a linker sequence of between 8 and 50 amino acids; Formula 4 is a zinc finger domain of the sequence X 2 C X 2,4 C X 5 X -1 X +1 X +2 X +3 X +4 X +5 X +6 H X 3,4,5 H / C and Formula 6 is a zinc finger domain of the sequence X 2 C X 2 C X 5 X -1 X +1 X +2 X +3 X +4 X +5 X +6 H X 3 H, wherein X is any amino acid, the numbers in subscript indicate the possible numbers of residues represented by X at that position, and the number in superscript indicates the position of the amino acid in the recognition sequence of the zinc finger domain; and wherein at least 8 adjacent zinc finger domains have a recognition sequence X -1 X +1 X +2 X +3 X +4 X +5 X +6 according to SEQ ID NO: 1; wherein the sequence of SEQ ID NO: 1 is selected from a combination of SEQ ID NOs: 2 and 5; from a combination of SEQ ID NOs: 3 and 4; from a combination of SEQ ID NOs: 2, 3 or 4, or from a combination of SEQ ID NOs: 3, 4 and 5.