A compound having the following structure: or a stereoisomer or pharmaceutically acceptable salt thereof, wherein: R 1 and R 2 are independently selected from the group consisting of: H and C 1-6 alkyl; or R 2 and R 5 are fused and form a ring; R 3 and R 4 are independently selected from the group consisting of: H and R; or R 3 and R 4 are joined to form a ring; R 5 is selected from the group consisting of: optionally substituted alkyl, optionally substituted alkylamino, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heterocyclyl and optionally substituted heteroaryl; or R 5 and R 2 are fused and form a ring; R 6 is H; R 7 and R 8 are independently selected from the group consisting of: H and R; and R 9 is: wherein, R is a saturated or unsaturated moiety having a linear, branched, or non-aromatic cyclic skeleton containing one to ten carbon atoms, zero to four nitrogen atoms, zero to four oxygen atoms, and zero to four sulfur atoms, and the carbon atoms are optionally independently substituted with: =O, =S, OH, -OR 10, -O 2 CR 10, -SH,-SR 10, -SOCR 10, -NH 2, -NHR 10, -N(R 10) 2, -NHCOR 10, -NR 10 COR 10, -I, -Br, -Cl, -F,-CN, -CO 2 H, -CO 2 R 10, -CHO, -COR 10, -CONH 2, -CONHR 10, -CON(R 10) 2, -COSH, -COSR 10, -NO 2, -SO 3 H, -SOR 10, or -SO 2 R 10, wherein R 10 is a linear, branched or cyclic, one to ten carbon saturated or unsaturated alkyl group; the ring formed by joining R 3 and R 4 is a three to seven member non-aromatic cyclic skeleton within the definition of R; Y is a linear, saturated or unsaturated, one to six carbon alkyl group, optionally substituted with R; and R 14 is selected from the group consisting of optionally substituted alkyl, optionally substituted alkylamino, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heterocyclyl and optionally substituted heteroaryl. R 1 and R 2 are independently selected from the group consisting of: H and C 1-6 alkyl; or R 2 and R 5 are fused and form a ring; R 3 and R 4 are independently selected from the group consisting of: H and R; or R 3 and R 4 are joined to form a ring; R 5 is selected from the group consisting of: optionally substituted alkyl, optionally substituted alkylamino, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heterocyclyl and optionally substituted heteroaryl; or R 5 and R 2 are fused and form a ring; R 6 is H; R 7 and R 8 are independently selected from the group consisting of: H and R; and R 9 is: wherein, R is a saturated or unsaturated moiety having a linear, branched, or non-aromatic cyclic skeleton containing one to ten carbon atoms, zero to four nitrogen atoms, zero to four oxygen atoms, and zero to four sulfur atoms, and the carbon atoms are optionally independently substituted with: =O, =S, OH, -OR 10, -O 2 CR 10, -SH,-SR 10, -SOCR 10, -NH 2, -NHR 10, -N(R 10) 2, -NHCOR 10, -NR 10 COR 10, -I, -Br, -Cl, -F,-CN, -CO 2 H, -CO 2 R 10, -CHO, -COR 10, -CONH 2, -CONHR 10, -CON(R 10) 2, -COSH, -COSR 10, -NO 2, -SO 3 H, -SOR 10, or -SO 2 R 10, wherein R 10 is a linear, branched or cyclic, one to ten carbon saturated or unsaturated alkyl group; the ring formed by joining R 3 and R 4 is a three to seven member non-aromatic cyclic skeleton within the definition of R; Y is a linear, saturated or unsaturated, one to six carbon alkyl group, optionally substituted with R; and R 14 is selected from the group consisting of optionally substituted alkyl, optionally substituted alkylamino, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heterocyclyl and optionally substituted heteroaryl. R is a saturated or unsaturated moiety having a linear, branched, or non-aromatic cyclic skeleton containing one to ten carbon atoms, zero to four nitrogen atoms, zero to four oxygen atoms, and zero to four sulfur atoms, and the carbon atoms are optionally independently substituted with: =O, =S, OH, -OR 10, -O 2 CR 10, -SH,-SR 10, -SOCR 10, -NH 2, -NHR 10, -N(R 10) 2, -NHCOR 10, -NR 10 COR 10, -I, -Br, -Cl, -F,-CN, -CO 2 H, -CO 2 R 10, -CHO, -COR 10, -CONH 2, -CONHR 10, -CON(R 10) 2, -COSH, -COSR 10, -NO 2, -SO 3 H, -SOR 10, or -SO 2 R 10, wherein R 10 is a linear, branched or cyclic, one to ten carbon saturated or unsaturated alkyl group; the ring formed by joining R 3 and R 4 is a three to seven member non-aromatic cyclic skeleton within the definition of R; Y is a linear, saturated or unsaturated, one to six carbon alkyl group, optionally substituted with R; and R 14 is selected from the group consisting of optionally substituted alkyl, optionally substituted alkylamino, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heterocyclyl and optionally substituted heteroaryl.