A tissue closure device, the tissue closure device (100, 200) comprising: an elongate body (110, 210) having a longitudinal axis, a sidewall of the elongate body being provided with a suture receiving recess (111, 211) extending from a proximal end to a distal end; an operating portion (120, 220) disposed at the proximal end of the elongate body (110, 210); a depth limiting mechanism comprising at least two wings (130, 230) disposed about the longitudinal axis, a proximal end of each wing (130, 230) being pivotally connected to the distal end of the elongate body (110, 220) about a pivot that is perpendicular to the longitudinal axis to allow movement of the wing (130, 230) between a folded position and an unfolded position, wherein the at least two wings (130, 230) together form an extension section of the elongate body (110, 210) when the at least two wings (130, 230) are in the folded position; and the at least two wings (130, 230) extend radially outward relative to the elongate body (110, 210) and together define a positioning plane at top surfaces of the at least two wings (130, 230) when the at least two wings (130, 230) are in the unfolded position, and the depth limiting mechanism is provided with a distal end engagement slot (131, 132, 231, 241) for clamping the suture, the distal end engagement (131, 132, 231, 241) slot being at least partially formed on the wing (130, 230), characterized in that the operating portion (120, 220) is provided with a proximal end engagement slot capable of clamping a suture, wherein the tissue closure device is configured to allow the suture to be retained between the proximal end engagement slot and the distal end engagement slot (131, 132, 231, 241) and received in the suture receiving recess (111, 211) prior to entry of the tissue closure device into a tissue, and to cause the suture to be stretched when the at least two wings (130, 230) are pivoted from the folded position to the unfolded position, so as to define a suture section (300a, 302) that can be gripped by an instrument, wherein the distal end engagement slot comprises a first distal end engagement slot (131, 241) and a second distal end engagement slot (132, 231), wherein the first distal end engagement slot and the second distal end engagement slot are arranged such that the defined suture section (300a, 302) that can be gripped by an instrument is positioned therebetween, the first distal end engagement slot (131, 241) and the second distal end engagement slot (132, 231) being configured to enable the suture to disengage from the first distal end engagement slot (131, 241) but remain engaged with the second distal end engagement slot (132. 231) when gripped by the instrument. an elongate body (110, 210) having a longitudinal axis, a sidewall of the elongate body being provided with a suture receiving recess (111, 211) extending from a proximal end to a distal end; an operating portion (120, 220) disposed at the proximal end of the elongate body (110, 210); a depth limiting mechanism comprising at least two wings (130, 230) disposed about the longitudinal axis, a proximal end of each wing (130, 230) being pivotally connected to the distal end of the elongate body (110, 220) about a pivot that is perpendicular to the longitudinal axis to allow movement of the wing (130, 230) between a folded position and an unfolded position, wherein the at least two wings (130, 230) together form an extension section of the elongate body (110, 210) when the at least two wings (130, 230) are in the folded position; and the at least two wings (130, 230) extend radially outward relative to the elongate body (110, 210) and together define a positioning plane at top surfaces of the at least two wings (130, 230) when the at least two wings (130, 230) are in the unfolded position, and the depth limiting mechanism is provided with a distal end engagement slot (131, 132, 231, 241) for clamping the suture, the distal end engagement (131, 132, 231, 241) slot being at least partially formed on the wing (130, 230), characterized in that the operating portion (120, 220) is provided with a proximal end engagement slot capable of clamping a suture, wherein the tissue closure device is configured to allow the suture to be retained between the proximal end engagement slot and the distal end engagement slot (131, 132, 231, 241) and received in the suture receiving recess (111, 211) prior to entry of the tissue closure device into a tissue, and to cause the suture to be stretched when the at least two wings (130, 230) are pivoted from the folded position to the unfolded position, so as to define a suture section (300a, 302) that can be gripped by an instrument, wherein the distal end engagement slot comprises a first distal end engagement slot (131, 241) and a second distal end engagement slot (132, 231), wherein the first distal end engagement slot and the second distal end engagement slot are arranged such that the defined suture section (300a, 302) that can be gripped by an instrument is positioned therebetween, the first distal end engagement slot (131, 241) and the second distal end engagement slot (132, 231) being configured to enable the suture to disengage from the first distal end engagement slot (131, 241) but remain engaged with the second distal end engagement slot (132. 231) when gripped by the instrument.