A pneumatic tire, preferably a heavy duty pneumatic tire or truck tire, the tire having a circumferential tread of a cap/base configuration comprising a circumferential outer tread cap rubber layer which contains a running surface for the tire and a tread base rubber layer at least partially underlying said tread cap rubber layer, wherein said tread cap rubber layer or said tread cap rubber layer and said tread base rubber layer comprises a rubber composition containing, based on parts by weight per 100 parts by weight elastomer (phr), 100 parts by weight conjugated diene-based elastomer(s) comprising: natural cis 1,4-polyisoprene rubber, or natural cis 1,4-polyisoprene rubber and from 5 up to 50 phr of an additional synthetic diene-based rubber comprising at least one of synthetic cis 1,4-polyisoprene rubber, cis 1,4 polybutadiene rubber and styrene/butadiene rubber; and 30 to 100 phr of a rubber reinforcing filler containing oxidized rubber reinforcing carbon black having from 3 to 8 percent of its surface containing a combination of carboxyl and hydroxyl groups, wherein the reinforcing filler is: carbon black comprising at least one of rubber reinforcing carbon black and said oxidized rubber reinforcing carbon black, provided that said carbon black contains from 25 to 100 weight percent of said oxidized carbon back, or a combination of precipitated silica and carbon black comprising from 5 to 40 weight percent of said silica, where said carbon black comprises at least one of rubber reinforcing carbon black and oxidized rubber reinforcing carbon black, provided that said carbon black contains from 25 to 100 weight percent of said oxidized rubber reinforcing carbon black, and further comprising a silica coupler having a moiety reactive with hydroxyl groups on the surface of the silica and another different moiety interactive with the conjugated diene-based elastomers. 100 parts by weight conjugated diene-based elastomer(s) comprising: natural cis 1,4-polyisoprene rubber, or natural cis 1,4-polyisoprene rubber and from 5 up to 50 phr of an additional synthetic diene-based rubber comprising at least one of synthetic cis 1,4-polyisoprene rubber, cis 1,4 polybutadiene rubber and styrene/butadiene rubber; and natural cis 1,4-polyisoprene rubber, or natural cis 1,4-polyisoprene rubber and from 5 up to 50 phr of an additional synthetic diene-based rubber comprising at least one of synthetic cis 1,4-polyisoprene rubber, cis 1,4 polybutadiene rubber and styrene/butadiene rubber; and 30 to 100 phr of a rubber reinforcing filler containing oxidized rubber reinforcing carbon black having from 3 to 8 percent of its surface containing a combination of carboxyl and hydroxyl groups, wherein the reinforcing filler is: carbon black comprising at least one of rubber reinforcing carbon black and said oxidized rubber reinforcing carbon black, provided that said carbon black contains from 25 to 100 weight percent of said oxidized carbon back, or a combination of precipitated silica and carbon black comprising from 5 to 40 weight percent of said silica, where said carbon black comprises at least one of rubber reinforcing carbon black and oxidized rubber reinforcing carbon black, provided that said carbon black contains from 25 to 100 weight percent of said oxidized rubber reinforcing carbon black, and further comprising a silica coupler having a moiety reactive with hydroxyl groups on the surface of the silica and another different moiety interactive with the conjugated diene-based elastomers. carbon black comprising at least one of rubber reinforcing carbon black and said oxidized rubber reinforcing carbon black, provided that said carbon black contains from 25 to 100 weight percent of said oxidized carbon back, or a combination of precipitated silica and carbon black comprising from 5 to 40 weight percent of said silica, where said carbon black comprises at least one of rubber reinforcing carbon black and oxidized rubber reinforcing carbon black, provided that said carbon black contains from 25 to 100 weight percent of said oxidized rubber reinforcing carbon black, and further comprising a silica coupler having a moiety reactive with hydroxyl groups on the surface of the silica and another different moiety interactive with the conjugated diene-based elastomers.