mhurhangee/ep-ind-claims huggingface dataset:
A method for determining the suitability of a neoepitope resulting from a disease-specific mutation at an allele in a gene (mutated allele) as a disease-specific target comprising determining, in a diseased cell or population of diseased cells, the copy number of the mutated allele encoding the neoepitope, wherein a copy number of the mutated allele which is greater than 2 indicates the suitability of the neoepitope as a disease-specific target, wherein the disease is cancer and wherein the higher the copy number of the mutated allele, the higher the suitability of the neoepitope as a disease-specific target.
Apraglutide, or a pharmaceutically acceptable salt thereof, for use in the treatment or prevention of acute gastrointestinal Graft versus Host Disease (GvHD) in a subject.
A continuous wrapping material for wrapping agricultural produce into round bales comprising: a plurality of wrapping units, each one of said plurality of wrapping units comprises a predetermined length of base wrapping material that extends in a longitudinal direction and terminates with a leading edge at one end thereof and a trailing edge at an opposing end thereof, said leading edge and said trailing edge both extend a predetermined length in a width direction that is transverse to said longitudinal direction and terminate at opposing lateral edges, said each one of said plurality of wrapping units also includes a first surface and an opposing second surface, said each one of said plurality of wrapping units is serially connected to at least another one of said plurality of wrapping units at least one of the corresponding leading and trailing edges forming a continuous wrapping material; and a first plurality of discrete spaced-apart adhesive areas disposed on said first surface of said each one of said plurality of wrapping units and a second plurality of discrete spaced- apart adhesive areas disposed on said second surface of said each one of said plurality of wrapping units; characterised in that each adhesive area of said first plurality of discrete adhesive areas is longitudinally spaced from the at least one other adhesive area and each adhesive area of said second plurality of discrete adhesive areas is longitudinally spaced from the at least one other adhesive area and said first plurality of discrete adhesive areas are longitudinally spaced from the second plurality of discrete adhesive areas so that, when the continuous wrapping material is rolled onto a roll core none of the first plurality of adhesive areas comes into face-to-face contact with any one or more of said second plurality of adhesive areas and when each wrapping unit is wrapped around an item each one of the first plurality of discrete adhesive areas comes into face-to-face contact with a corresponding one of the second plurality of discrete adhesive areas.
A ceramic-wound-capacitor comprising: a first-electrically-conductive-layer that defines an exposed-surface; a dielectric-layer formed of lead-lanthanum-zirconium-titanate (PLZT) in direct contact with the first-electrically-conductive-layer opposite the exposed-surface; a second-electrically-conductive-layer in direct contact with the dielectric-layer opposite the first-electrically-conductive-layer; and characterised in including a protective-coating in direct contact with the exposed-surface, said protective-coating, being on the opposite surface of the first conductive layer to the dielectric layer, and having a thickness of less than 10 micrometers, wherein the first-electrically-conductive-layer, the dielectric-layer, the second-electrically-conductive-layer, and the protective-coating form a capacitive-element, and the capacitive-element is wound to form the ceramic-wound-capacitor. a first-electrically-conductive-layer that defines an exposed-surface; a dielectric-layer formed of lead-lanthanum-zirconium-titanate (PLZT) in direct contact with the first-electrically-conductive-layer opposite the exposed-surface; a second-electrically-conductive-layer in direct contact with the dielectric-layer opposite the first-electrically-conductive-layer; and characterised in including a protective-coating in direct contact with the exposed-surface, said protective-coating, being on the opposite surface of the first conductive layer to the dielectric layer, and having a thickness of less than 10 micrometers, wherein the first-electrically-conductive-layer, the dielectric-layer, the second-electrically-conductive-layer, and the protective-coating form a capacitive-element, and the capacitive-element is wound to form the ceramic-wound-capacitor.
Undershot gate system to control flow of liquid through an open channel or pipe, said system including a gate leaf adapted to be raised and lowered by a control means to allow flow of liquid along said open channel or pipe, a plurality of pairs of acoustic transducers (22, 24) forming an acoustic array (18, 20) on opposing sides of the open channel or pipe to provide, in use, a plurality of multiple planes of crossed acoustic path for measurements of flow velocity through the gate opening, characterised in that the gate leaf includes a flow diverter at an end of the gate leaf to guide liquid under said gate leaf and through the gate opening when the gate leaf is in an open position and a means to measure the height of the opening of the gate leaf.
A method for the layer-wise building of bodies, comprising at least the following steps: a) combining of at least one refractory mold base material and at least one ester in order to obtain an ester-impregnated mold material mixture, b) spreading of a thin layer having a layer thickness of 1 to 6, preferably 1 to 5, particularly preferably 1 to 3, grains of the ester-impregnated mold material mixture, c) printing of selected areas of the thin layer with a binder comprising at least resoles for curing the areas, d) multiple repetitions of steps b) and c) for the fabrication of at least a partially cured three-dimensional body. a) combining of at least one refractory mold base material and at least one ester in order to obtain an ester-impregnated mold material mixture, b) spreading of a thin layer having a layer thickness of 1 to 6, preferably 1 to 5, particularly preferably 1 to 3, grains of the ester-impregnated mold material mixture, c) printing of selected areas of the thin layer with a binder comprising at least resoles for curing the areas, d) multiple repetitions of steps b) and c) for the fabrication of at least a partially cured three-dimensional body.
A paper product with three or more plies, comprising a first outer embossed ply, a second outer embossed ply and an embossed middle ply; said first outer embossed ply has a first set of protrusions and a second set of protrusions, obtained by means of a first embossing step; said protrusions of the second set are higher than said protrusions of the first set; said second outer ply has a first set of protrusions obtained in a first step of embossing of said second outer ply; said first outer ply and said middle ply are mated to said second outer ply by lamination; said paper product being characterized in that said middle ply comprises a set of intermediate protrusions provided on said middle ply during a second embossing operation; said second set of protrusions of said first outer embossed ply corresponding to said set of intermediate protrusions; said first outer ply and said middle ply being glued at said second sets of protrusions (22, 42).
A method for assisting the judgment of the prognosis for a patient with breast cancer, the method comprising the steps of: detecting ACTN4 gene contained in a biological sample of the patient; and judging that the prognosis of breast cancer is poor if the copy number of ACTN4 gene is 5 or more and/or the gene amplification of ACTN4 gene is present; wherein the patient is HER2 negative, hormone receptor positive and lymph node metastasis negative. detecting ACTN4 gene contained in a biological sample of the patient; and judging that the prognosis of breast cancer is poor if the copy number of ACTN4 gene is 5 or more and/or the gene amplification of ACTN4 gene is present; wherein the patient is HER2 negative, hormone receptor positive and lymph node metastasis negative.
A pharmaceutical composition comprising an agent selected from 1-(N-(2-(diethylamino)ethyl)-N-(4-(4-trifluoromethylphenyl)benzyl)-aminocarbonylmethyl)-2-(4-fluorobenzyl)thio-5,6-trimethylenepyrimidin-4-one, N-(2-diethylaminoethyl)-2-[2-(2-(2,3-difluorophenyl)ethyl)-4-oxo-4,5,6,7-tetrahydro-cyclopentapyrimidin-1-yl]- N -(4'-trifluoromethyl-biphenyl-4-ylmethyl)acetamide, N -(1-(2-methoxyethyl)piperidin-4-yl)-2-[2-(2,3-difluorobenzylthio)-4-oxo-4H-quinolin-1-yl]- N -(4'-trifluoromethylbiphenyl-4-ylmethyl)-acetamide, or methyl 2-[4-({[2-[2-(2,3-difluorophenyl)ethyl]-4-oxopyrido[2,3-d]pyrimidm-1 -yl]acetyl}{[4'-(trifluoromethyl)-4-biphenylyl]methyl}amino)-1-piperidinyl]-2-methylpropanoate, or a pharmaceutically acceptable salt or ester of said agent, for use in a method of treating and/or preventing skin ulcers in a subject, comprising determining whether said subject has or is at risk of having a skin ulcer, and administering the pharmaceutical composition to the subject having a skin ulcer or at risk of developing a skin ulcer.
A carded web comprising a plurality of staple fibers formed from a monofilament fiber comprising at least one polymeric resin, wherein the polymeric resin is polypropylene, and at least one coated filler, wherein the at least one coated filler has an average particle size of less than or equal to 3 microns, more preferably less than or equal to 2 microns, and most preferably less than or equal to 1.5 microns, wherein the at least one coated filler is ground calcium carbonate coated with at least one organic material chosen from fatty acids and salts and esters thereof and wherein the top cut is less than the diameter of the fiber, wherein the top cut refers to the largest particle size that can be identified in a sample of filler by a MICROTRAC® 100 particle size analyzer and wherein the at least one coated filler is present in the staple fibers in an amount less than or equal to 20 wt%, relative to the total weight of the staple fibers.
A dye-sensitized solar cell comprises an electrolyte composition as electrolyte in which the electrolyte composition comprises ionic liquid and a redox couple, characterized in that the ionic liquid includes dicyanamide anions as anions and cations having quaternized nitrogen atom, and that the redox couple is a halogen type redox couple obtained by reacting halogen molecules with halide ions, and that the cations are selected from a group consisting of quaternary ammonium, pyridinium with quaternized nitrogen atom, and pyrrolidinium with quaternized nitrogen atom.
An air inlet plenum for a gas turbine engine, comprising: a hollow body having an air inlet aperture and an air outlet aperture arranged and configured for connection to the gas turbine engine; at least one removable portion (23L,23R), which is removable from the hollow body when the air inlet plenum is connected to a gas turbine engine; characterised in that: the air inlet plenum is at least partly made of fiber-reinforced plastic; and said air outlet is provided with a connection flange formed by at least two flange portions (23L, 23R), wherein at least one of said flange portions is removable from the hollow body and forms said at least one removable portion of the air inlet plenum.
An immungenie composition comprising a Leptospira interrogans serovar hardjo (type hardjoprajitno) and Leptospira serovars canicola, grippotyphosa, icterohaemorrhagiae, and pomona and an adjuvant for use in a method for provoking an immune response against Leptospira borgpetersenii serovar hardjo (type hardjo-bovis) in a subject wherein the immune response provides protection against, reduction in the incidence, and/or lessens the severity of infection by Leptospira borgpetersenii serovar hardjo (type hardjo-bovis) in a subject, wherein the Leptospira interrogans serovar hardjo (type hardjoprajitno) is a killed bacterium.
A method for evaluating adhesive strength among coal particles of different coal brands using interfacial tension determined on the basis of the surface tension of each kind of coal brand as an index, wherein the surface tension of each kind of coal brand is measured in cooled coal after heating the coal in an inert atmosphere to a temperature in which coal particles begin softening and cooling the heated coal at a cooling rate of 10°C/sec or more, and wherein the value of interfacial tension is calculated from the measured values of surface tension and the blending ratios of the two kinds of heat treated coals and wherein the adhesive strength is evaluated based on a value of interfacial tension between two kinds of heat treated coals obtained by heat treating the two kinds of coals, and wherein the adhesive strength among coal particles is evaluated as poor when the value of interfacial tension is more than a prescribed threshold. wherein the surface tension of each kind of coal brand is measured in cooled coal after heating the coal in an inert atmosphere to a temperature in which coal particles begin softening and cooling the heated coal at a cooling rate of 10°C/sec or more, and wherein the value of interfacial tension is calculated from the measured values of surface tension and the blending ratios of the two kinds of heat treated coals and wherein the adhesive strength is evaluated based on a value of interfacial tension between two kinds of heat treated coals obtained by heat treating the two kinds of coals, and wherein the adhesive strength among coal particles is evaluated as poor when the value of interfacial tension is more than a prescribed threshold.
A booster assembly (412,512,612) comprising at least one turbine unit and at least one booster apparatus (10,210,310,510), the booster apparatus (10,210,310,510) comprises a booster housing adapted to be connected to an outlet of the turbine unit whereby a second fluid passes along a fluid path extending through the turbine unit and passing into the booster housing, the at least one turbine unit comprising one or more drive turbine blade sets located upstream from one or more pump turbine blade sets mounted within a passage of a turbine housing, the one or more drive turbine blade sets and the one or more pump turbine blade sets are mounted on a common shaft such that they are confined to rotate in the same direction and same speed, the booster apparatus (10,210,310,510) having at least one inlet (124,323,523) through which a first fluid passes to be entrained in the second fluid as the second fluid is flowing through the booster housing, the booster assembly further comprising a flow regulator (436,636) for regulating the volume and velocity of the second fluid passing through the booster assembly, the flow regulator (436,636) comprises a valve head (438,638) adapted to be variably positioned along the fluid path, the valve head (438,638) is supported on the shaft, wherein the shaft is rotatable relative to the valve head (438,638).
A computer program product for calculating a synthetic CT image, wherein the computer program product comprises machine executable instructions for execution by a processor, wherein execution of the machine executable instructions causes the processor to: - receive bone mineralization density data; - receive a magnetic resonance image of a region of interest; - calculate an image segmentation by segmenting the magnetic resonance image into a set of tissue types, wherein the set of tissue types comprises a cortical bone segmentation; - calculate a cortical bone Hounsfield value using the bone mineralization density data; - calculate a Hounsfield unit mapping by assigning at least one Hounsfield unit value to each of the set of tissue types in the image segmentation, wherein the cortical bone segmentation is assigned the cortical bone Hounsfield value; and - calculate the synthetic CT image using the Hounsfield unit mapping. - receive bone mineralization density data; - receive a magnetic resonance image of a region of interest; - calculate an image segmentation by segmenting the magnetic resonance image into a set of tissue types, wherein the set of tissue types comprises a cortical bone segmentation; - calculate a cortical bone Hounsfield value using the bone mineralization density data; - calculate a Hounsfield unit mapping by assigning at least one Hounsfield unit value to each of the set of tissue types in the image segmentation, wherein the cortical bone segmentation is assigned the cortical bone Hounsfield value; and - calculate the synthetic CT image using the Hounsfield unit mapping.
Use of an allergen inactivating agent for inactivating an allergen in house dust, wherein the allergen inactivating agent consists of (a), (b) and (c): (a) titanium oxide having a photocatalytic activity and an average particle size of the primary particle of from 1 to 30 nm; (b) a solvent that is water, an alcohol having from 1 to 5 carbon atoms, or a mixture thereof; and (c) one or more of a dispersant, a deodorant, a mildewproof preservative, an antistatic agent, a brightener, a pH adjusting agent and a texture improver. (a) titanium oxide having a photocatalytic activity and an average particle size of the primary particle of from 1 to 30 nm; (b) a solvent that is water, an alcohol having from 1 to 5 carbon atoms, or a mixture thereof; and (c) one or more of a dispersant, a deodorant, a mildewproof preservative, an antistatic agent, a brightener, a pH adjusting agent and a texture improver.
A thermally conductive polysiloxane composition comprising: a thermally conductive filler; a siloxane compound having an alkoxysilyl group and a linear siloxane structure; a polyorganosiloxane having at least two alkenyl groups bonded to silicon atoms per molecule; a linear polyorganohydrogensiloxane represented by the following general formula: wherein, R 7 is a hydrogen atom, R 8 is each independently a monovalent hydrocarbon group having no aliphatic unsaturated bond and having 1 to 12 carbon atoms, and f is 1 to 200; a polyorganohydrogensiloxane having per molecule at least three units represented by the following general formula: R 9 g R 10 h SiO ({4 - (g + h)}/2) wherein, R 9 is each independently a monovalent hydrocarbon group having no aliphatic unsaturated bond and having 1 to 12 carbon atoms, R 10 is a hydrogen atom, g is an integer of 0 to 2, h is an integer of 1 or 2, and g + h is an integer of 1 to 3, with the proviso that a case in which g is 1 and h is 1 is excluded; and a platinum catalyst. a thermally conductive filler; a siloxane compound having an alkoxysilyl group and a linear siloxane structure; a polyorganosiloxane having at least two alkenyl groups bonded to silicon atoms per molecule; a linear polyorganohydrogensiloxane represented by the following general formula: wherein, R 7 is a hydrogen atom, R 8 is each independently a monovalent hydrocarbon group having no aliphatic unsaturated bond and having 1 to 12 carbon atoms, and f is 1 to 200; R 7 is a hydrogen atom, R 8 is each independently a monovalent hydrocarbon group having no aliphatic unsaturated bond and having 1 to 12 carbon atoms, and f is 1 to 200; a polyorganohydrogensiloxane having per molecule at least three units represented by the following general formula: R 9 g R 10 h SiO ({4 - (g + h)}/2) wherein, R 9 is each independently a monovalent hydrocarbon group having no aliphatic unsaturated bond and having 1 to 12 carbon atoms, R 10 is a hydrogen atom, g is an integer of 0 to 2, h is an integer of 1 or 2, and g + h is an integer of 1 to 3, with the proviso that a case in which g is 1 and h is 1 is excluded; and R 9 is each independently a monovalent hydrocarbon group having no aliphatic unsaturated bond and having 1 to 12 carbon atoms, R 10 is a hydrogen atom, g is an integer of 0 to 2, h is an integer of 1 or 2, and g + h is an integer of 1 to 3, with the proviso that a case in which g is 1 and h is 1 is excluded; and a platinum catalyst.
A method for itinerary planning for a vehicle which has a navigation unit installed on board and adapted to gathering, collating and presenting navigation information comprising the vehicle's weight/ length/ height, which method comprises: transferring the navigation information related to the vehicle comprising the vehicle's weight/length/height from the navigation unit on board the vehicle to a portable unit, planning the itinerary in the portable unit at a location outside the vehicle based on the transferred navigation information, by inputting starting point, inputting destination, calculating length of time and/ or fuel consumption for at least one itinerary, receiving the planned itinerary in the vehicle's navigation unit from the portable unit and introducing the itinerary received into the vehicle's navigation unit. transferring the navigation information related to the vehicle comprising the vehicle's weight/length/height from the navigation unit on board the vehicle to a portable unit, planning the itinerary in the portable unit at a location outside the vehicle based on the transferred navigation information, by inputting starting point, inputting destination, calculating length of time and/ or fuel consumption for at least one itinerary, receiving the planned itinerary in the vehicle's navigation unit from the portable unit and introducing the itinerary received into the vehicle's navigation unit.
A grounded antenna with cross-shaped high-impedance surface metal strips, comprising an antenna radiating element and a ground plate thereof; wherein multiple high-impedance surface units are arranged on the ground plate in intervals; each high-impedance surface unit is composed of two high-impedance surface metal strips to form a cross; a high-impedance surface through hole is made at the intersection of the cross; and with the high-impedance surface through holes the high-impedance surface units connect with each other, wherein the cross-shaped high-impedance surface units are arranged on the ground plate in at least one of rows or lines and at least one high-impedance surface metal strip is inclined to the rows or lines formed by the high-impedance surface units.
A ring type wearable terminal comprising: a first ring that has a recessed portion formed on a side surface thereof; a second ring that covers the recessed portion; and a communication unit that is housed in the recessed portion, wherein the recessed portion is filled with an adhesive agent, characterised in that: the second ring is bonded to the first ring by the adhesive agent; wherein a notch that is filled with the adhesive agent is formed on a side edge portion of at least one of the first ring and the second ring. a first ring that has a recessed portion formed on a side surface thereof; a second ring that covers the recessed portion; and a communication unit that is housed in the recessed portion, wherein the recessed portion is filled with an adhesive agent, characterised in that: the second ring is bonded to the first ring by the adhesive agent; wherein a notch that is filled with the adhesive agent is formed on a side edge portion of at least one of the first ring and the second ring. the second ring is bonded to the first ring by the adhesive agent; wherein a notch that is filled with the adhesive agent is formed on a side edge portion of at least one of the first ring and the second ring.