A syringe comprising: a cylindrically-shaped gasket comprising a closed distal end, an open proximal end, and an inner cavity portion extending distally from a proximal side; a barrel comprising a distal opening portion and configured to slidably store the gasket; and a plunger comprising a head portion configured to be stored in the inner cavity portion of the gasket, wherein the plunger comprises a helical rib provided at the head portion, the helical rib comprising a starting end on a distal side and a terminal end on a proximal side, wherein the gasket comprises, on an inner surface of the inner cavity portion, a helical crest portion forming a helical valley portion configured to threadedly engage with the helical rib of the plunger, and a plunger-retaining annular rib positioned distally from the helical crest portion, wherein the inner cavity portion further comprises an accommodation portion positioned distally from the plunger-retaining annular rib, the accommodation portion configured to store a part of the head portion of the plunger at which the helical rib is formed, and wherein the plunger-retaining annular rib further comprises a rib absent portion configured to guide, to the accommodation portion, the helical rib reaching the plunger-retaining annular rib as threaded engagement is advanced between the plunger and the gasket, and wherein the plunger comprises, at the terminal end of the helical rib, an entrance-restricting terminal end portion configured to restrict the entrance of the helical rib into the rib absent portion, after the part of the plunger at which the helical rib is formed is stored in the accommodation portion of the gasket, characterized in that the head portion comprises a shaft portion comprising the helical rib on an outer surface, and the entrance-restricting terminal end portion of the helical rib comprises an inclined terminal end surface formed at the terminal end of the helical rib, wherein the inclined terminal end surface is configured to be directed obliquely by a predetermined angle to the axis of the shaft portion of the plunger, and the inclined terminal end surface is directed toward the proximal end of the plunger. a cylindrically-shaped gasket comprising a closed distal end, an open proximal end, and an inner cavity portion extending distally from a proximal side; a barrel comprising a distal opening portion and configured to slidably store the gasket; and a plunger comprising a head portion configured to be stored in the inner cavity portion of the gasket, wherein the plunger comprises a helical rib provided at the head portion, the helical rib comprising a starting end on a distal side and a terminal end on a proximal side, wherein the gasket comprises, on an inner surface of the inner cavity portion, a helical crest portion forming a helical valley portion configured to threadedly engage with the helical rib of the plunger, and a plunger-retaining annular rib positioned distally from the helical crest portion, wherein the inner cavity portion further comprises an accommodation portion positioned distally from the plunger-retaining annular rib, the accommodation portion configured to store a part of the head portion of the plunger at which the helical rib is formed, and wherein the plunger-retaining annular rib further comprises a rib absent portion configured to guide, to the accommodation portion, the helical rib reaching the plunger-retaining annular rib as threaded engagement is advanced between the plunger and the gasket, and wherein the plunger comprises, at the terminal end of the helical rib, an entrance-restricting terminal end portion configured to restrict the entrance of the helical rib into the rib absent portion, after the part of the plunger at which the helical rib is formed is stored in the accommodation portion of the gasket, characterized in that the head portion comprises a shaft portion comprising the helical rib on an outer surface, and the entrance-restricting terminal end portion of the helical rib comprises an inclined terminal end surface formed at the terminal end of the helical rib, wherein the inclined terminal end surface is configured to be directed obliquely by a predetermined angle to the axis of the shaft portion of the plunger, and the inclined terminal end surface is directed toward the proximal end of the plunger.