A process for the preparation of a drug delivery device characterized by: providing a substrate (42,202) comprising a sheet form edible flexible material substrate base having a sticky substance applied thereto wherein the sticky substance extends over part of one surface of the sheet form substrate (42,202) and comprises a sticky patch on part of the surface of the substrate (42,202) bordered or surrounded by areas of non-sticky substance, isolating a unit of the substrate (42,202) comprising a defined area of the sticky substance by positioning a mask adjacent to the sticky substance, the mask having one or more aperture through which a particulate drug substance (210, 411) may pass and come into contact with the region of the sticky substance defined by the aperture, the aperture of the mask defining the area of the sticky substance into contact with which the particulate drug substance (210, 411) comes, bringing the particulate drug substance (210, 411) into contact with the sticky substance through the aperture so that particulate drug substance (210, 411) becomes stuck to the sticky substance, removing excess particulate drug substance (210, 411) from the substrate (42,202) which has not become stuck thereto, forming a unit of the substrate (42,202) comprising an area of the sticky substance having the particulate drug substance (210, 411) stuck thereto by sub-dividing the substrate (42,202) to isolate one or more area of the sticky substance with particulate drug substance (210,411) stuck thereon by cutting through areas of the substrate (42,202) which have no sticky substance thereon, then the unit of substrate (42,202) is further processed, after the sticking of the particulate drug substance (210,411) thereto, into a form suitable for use as a drug substance delivery device by compaction in which the sheet form substrate (42,202) is compacted by rolling the sheet form substrate (42,202) into a cylinder, folding, or stacking isolated units of the substrate and enclosing the compacted sheet-form substrate (42,202) in a carrier which is a compacted tablet or capsule. providing a substrate (42,202) comprising a sheet form edible flexible material substrate base having a sticky substance applied thereto wherein the sticky substance extends over part of one surface of the sheet form substrate (42,202) and comprises a sticky patch on part of the surface of the substrate (42,202) bordered or surrounded by areas of non-sticky substance, isolating a unit of the substrate (42,202) comprising a defined area of the sticky substance by positioning a mask adjacent to the sticky substance, the mask having one or more aperture through which a particulate drug substance (210, 411) may pass and come into contact with the region of the sticky substance defined by the aperture, the aperture of the mask defining the area of the sticky substance into contact with which the particulate drug substance (210, 411) comes, bringing the particulate drug substance (210, 411) into contact with the sticky substance through the aperture so that particulate drug substance (210, 411) becomes stuck to the sticky substance, removing excess particulate drug substance (210, 411) from the substrate (42,202) which has not become stuck thereto, forming a unit of the substrate (42,202) comprising an area of the sticky substance having the particulate drug substance (210, 411) stuck thereto by sub-dividing the substrate (42,202) to isolate one or more area of the sticky substance with particulate drug substance (210,411) stuck thereon by cutting through areas of the substrate (42,202) which have no sticky substance thereon, then the unit of substrate (42,202) is further processed, after the sticking of the particulate drug substance (210,411) thereto, into a form suitable for use as a drug substance delivery device by compaction in which the sheet form substrate (42,202) is compacted by rolling the sheet form substrate (42,202) into a cylinder, folding, or stacking isolated units of the substrate and enclosing the compacted sheet-form substrate (42,202) in a carrier which is a compacted tablet or capsule.