A host unit of a distributed antenna system, wherein the host unit is configured to be coupled to a base station, the host unit comprising: at least one of: a baseband processor configured to receive Internet Protocol data from an IP gateway, wherein the baseband processor is configured to perform baseband processing to place the IP data onto a channel, wherein the baseband processor is configured to convert between IP data and baseband, digital data; or an interface configured to communicate baseband, digital data with a base station; the host unit further comprising: an radio frequency module (208, 210, 212) configured to communicate with a base station using RF signals configured for communication over an antenna, the RF module (208, 210, 212) configured to convert between the RF signals configured for communication over an antenna and RF sampled data; and a serial interface configured to convert between the RF sampled data and one or more serial data streams, wherein the serial interface is further configured to convert between the baseband, digital data and one or more second serial data streams; wherein the host unit is configured to provide the one or more serial data streams and the one or more second serial data streams to a communication medium for transmission to a remote unit of the distributed antenna system. at least one of: a baseband processor configured to receive Internet Protocol data from an IP gateway, wherein the baseband processor is configured to perform baseband processing to place the IP data onto a channel, wherein the baseband processor is configured to convert between IP data and baseband, digital data; or an interface configured to communicate baseband, digital data with a base station; a baseband processor configured to receive Internet Protocol data from an IP gateway, wherein the baseband processor is configured to perform baseband processing to place the IP data onto a channel, wherein the baseband processor is configured to convert between IP data and baseband, digital data; or an interface configured to communicate baseband, digital data with a base station; the host unit further comprising: an radio frequency module (208, 210, 212) configured to communicate with a base station using RF signals configured for communication over an antenna, the RF module (208, 210, 212) configured to convert between the RF signals configured for communication over an antenna and RF sampled data; and a serial interface configured to convert between the RF sampled data and one or more serial data streams, wherein the serial interface is further configured to convert between the baseband, digital data and one or more second serial data streams; wherein the host unit is configured to provide the one or more serial data streams and the one or more second serial data streams to a communication medium for transmission to a remote unit of the distributed antenna system. an radio frequency module (208, 210, 212) configured to communicate with a base station using RF signals configured for communication over an antenna, the RF module (208, 210, 212) configured to convert between the RF signals configured for communication over an antenna and RF sampled data; and a serial interface configured to convert between the RF sampled data and one or more serial data streams, wherein the serial interface is further configured to convert between the baseband, digital data and one or more second serial data streams; wherein the host unit is configured to provide the one or more serial data streams and the one or more second serial data streams to a communication medium for transmission to a remote unit of the distributed antenna system.