mhurhangee/ep-ind-claims huggingface dataset:
A method of manufacturing a device, comprising: mounting a surface mount component to a substrate using a set of discrete mechanical coupling parts (20;30;32;34), the surface mount component and the mechanical coupling parts (20;30;32;34) being connected by a clamp or clicking system such that the surface mount component is a snap fit to the mechanical coupling parts, and the method further comprises forming the mechanical coupling parts (20;30;32;34) as integral components with the substrate or directly over the substrate and providing a statically determinate coupling between the substrate and the surface mount component; and after mounting the surface mount component to the substrate providing a bonding layer providing electrical and/or thermal interconnection between the surface mount component and the substrate; the method being characterized in that the mechanical coupling parts (20; 30; 32; 34) are formed by 3D printing on the substrate or by 3D machining of the substrate. mounting a surface mount component to a substrate using a set of discrete mechanical coupling parts (20;30;32;34), the surface mount component and the mechanical coupling parts (20;30;32;34) being connected by a clamp or clicking system such that the surface mount component is a snap fit to the mechanical coupling parts, and forming the mechanical coupling parts (20;30;32;34) as integral components with the substrate or directly over the substrate and providing a statically determinate coupling between the substrate and the surface mount component; and after mounting the surface mount component to the substrate providing a bonding layer providing electrical and/or thermal interconnection between the surface mount component and the substrate; the method being characterized in that the mechanical coupling parts (20; 30; 32; 34) are formed by 3D printing on the substrate or by 3D machining of the substrate.
A compound of general formula wherein: R 1 is selected from the group consisting of phenyl, 6 membered heteroaryl, phenoxy and 6 membered heteroaryloxy; all of which are optionally substituted with one or more substituents independently selected from R 3; and R 2 is selected from the group consisting of (C 3 -C 7)cycloalkyl, bridged (C 3 -C 7)cycloalkyl and (4-7 membered) heterocycloalkyl; all of which are optionally substituted with one or more substituents independently selected from R 4; and R 3 is selected from the group consisting of halogen, -CN, (C 1 -C 4)alkyl, halo(C 1 -C 4)alkyl, hydroxy(C 1 -C 4)alkyl and (C 3 -C 6)cycloalkyl; and R 4 is selected from the group consisting of fluoro, -CN, -OH, (C 1 -C 4)alkyl, halo(C 1 -C 4)alkyl, hydroxy(C 1 -C 4)alkyl, -OR x, -S 2 R x, -S 2 NR a R b, -C R x, -C (OR x), and -C NR a R b; and R x is selected from the group consisting of (C 1 -C 4)alkyl and (C 3 -C 6)cycloalkyl; and R a and R b are independently selected from the group consisting of hydrogen, (C 1 -C 4)alkyl and (C 3 -C 6)cycloalkyl; and represents a chiral sulfur atom with stereochemistry; or pharmaceutically acceptable salts, enantiomers, mixtures of enantiomers, diastereomers, mixtures of diastereomers, hydrates and solvates thereof. R 1 is selected from the group consisting of phenyl, 6 membered heteroaryl, phenoxy and 6 membered heteroaryloxy; all of which are optionally substituted with one or more substituents independently selected from R 3; and R 2 is selected from the group consisting of (C 3 -C 7)cycloalkyl, bridged (C 3 -C 7)cycloalkyl and (4-7 membered) heterocycloalkyl; all of which are optionally substituted with one or more substituents independently selected from R 4; and R 3 is selected from the group consisting of halogen, -CN, (C 1 -C 4)alkyl, halo(C 1 -C 4)alkyl, hydroxy(C 1 -C 4)alkyl and (C 3 -C 6)cycloalkyl; and R 4 is selected from the group consisting of fluoro, -CN, -OH, (C 1 -C 4)alkyl, halo(C 1 -C 4)alkyl, hydroxy(C 1 -C 4)alkyl, -OR x, -S 2 R x, -S 2 NR a R b, -C R x, -C (OR x), and -C NR a R b; and R x is selected from the group consisting of (C 1 -C 4)alkyl and (C 3 -C 6)cycloalkyl; and R a and R b are independently selected from the group consisting of hydrogen, (C 1 -C 4)alkyl and (C 3 -C 6)cycloalkyl; and represents a chiral sulfur atom with stereochemistry; or pharmaceutically acceptable salts, enantiomers, mixtures of enantiomers, diastereomers, mixtures of diastereomers, hydrates and solvates thereof.
A thermoelectric generator assembly, comprising: a thermoelectric generator having a thermoelectric element and spaced-apart hot and cold junction flanges (204, 206) that comprise enlarged flat plates that overhang the thermoelectric element and are larger than the thermoelectric element, the hot junction flange having an adapter shaped for thermally coupling to a process vessel; a heat sink thermally coupled to ambient air and having a heat sink flange; and a heat pipe assembly comprising a fluid in a circulation chamber, the circulation chamber having an evaporator flange mounted to the cold junction flange and a condenser flange mounted to the heat sink flange, at least a portion of the fluid transporting heat from the evaporator flange to the condenser flange. a thermoelectric generator having a thermoelectric element and spaced-apart hot and cold junction flanges (204, 206) that comprise enlarged flat plates that overhang the thermoelectric element and are larger than the thermoelectric element, the hot junction flange having an adapter shaped for thermally coupling to a process vessel; a heat sink thermally coupled to ambient air and having a heat sink flange; and a heat pipe assembly comprising a fluid in a circulation chamber, the circulation chamber having an evaporator flange mounted to the cold junction flange and a condenser flange mounted to the heat sink flange, at least a portion of the fluid transporting heat from the evaporator flange to the condenser flange.
Process for manufacturing products made of composite materials, characterized in that it comprises the following operative steps: - arranging one or more substrates in at least one cavity (24, 41) of at least one mould (16, 36) made of a composite material; - hermetically closing the mould (16, 36) by means of mechanic fastening devices (20, 34, 37, 48, 55) comprising a plurality of bushings (20, 37) incorporated in the mould (16, 36); - evacuating the cavity (24, 41) and injecting resin into the cavity (24, 41) at a pressure comprised between 0,5 bar and 3,5 bar, in particular comprised between 1,5 and 2,5 bar, so that the substrates are impregnated by the injected resin; - heating the mould (16, 36) for curing the resin which impregnates the substrates in the cavity (24, 41). - arranging one or more substrates in at least one cavity (24, 41) of at least one mould (16, 36) made of a composite material; - hermetically closing the mould (16, 36) by means of mechanic fastening devices (20, 34, 37, 48, 55) comprising a plurality of bushings (20, 37) incorporated in the mould (16, 36); - evacuating the cavity (24, 41) and injecting resin into the cavity (24, 41) at a pressure comprised between 0,5 bar and 3,5 bar, in particular comprised between 1,5 and 2,5 bar, so that the substrates are impregnated by the injected resin; - heating the mould (16, 36) for curing the resin which impregnates the substrates in the cavity (24, 41).
Method of indicating the degree of ageing experienced by a tire as it is being driven on by a vehicle, characterized in that the temperature is measured locally at at least one point of the tire, in that the time of exposure to the said temperature is measured and in that these measurements are analyzed using a model of the said tire.
An aircraft headrest adjusting bracket comprising: a bracket body having a first side and a second side, the bracket body defining at least two headrest post engaging portions (102, 104) and an internal gap separating the first side and the second side; at least two protrusions (112, 114) disposed on an interior surface defining the internal gap, each proximal to a corresponding headrest post engaging portion; and a tensioning element engaging the first side and the second side, wherein the tensioning element is configured to displace the first side toward the second side to create tension between the bracket body and headrests posts disposed within the at least two headrest post engaging portions and the at least two protrusions are disposed to contact the headrest posts when inserted into the at least two headrest post engaging portions to increase surface area contact with the headrest posts when the tension element displaces the first side toward the second side. a bracket body having a first side and a second side, the bracket body defining at least two headrest post engaging portions (102, 104) and an internal gap separating the first side and the second side; at least two protrusions (112, 114) disposed on an interior surface defining the internal gap, each proximal to a corresponding headrest post engaging portion; and a tensioning element engaging the first side and the second side, wherein the tensioning element is configured to displace the first side toward the second side to create tension between the bracket body and headrests posts disposed within the at least two headrest post engaging portions and the at least two protrusions are disposed to contact the headrest posts when inserted into the at least two headrest post engaging portions to increase surface area contact with the headrest posts when the tension element displaces the first side toward the second side.
A feeder for presenting components (230, 232) comprising: a container for holding the components, the container having sloped interior walls and a passage; an elongated pedestal having a plurality of flat upper surfaces, the pedestal being reciprocally mounted for movement through the passage along a longitudinal axis (a); and an actuator for moving the pedestal along the longitudinal axis between a low position and a high position, wherein the feeder is adapted so that: when the pedestal is in the low position, the flat upper surfaces of the pedestal are substantially below a rim of the container and the interior walls of the container direct the components onto the flat upper surfaces of the pedestal and when the pedestal is in the high position, a plurality of select components are on the flat upper surfaces, characterized in that the elongated pedestal has ribs and a plurality of channels formed between the ribs, the ribs defining the plurality of flat upper surfaces and comprising a depth and a length, wherein the length of the ribs varies with distance from a center of the pedestal, wherein the pedestal is adapted so that: as the pedestal moves from the low position to the high position, a plurality of excess components are dispersed through the channels; and when the pedestal is in the high position, a plurality of select components are isolated, on the flat upper surfaces, from the other components. a container for holding the components, the container having sloped interior walls and a passage; an elongated pedestal having a plurality of flat upper surfaces, the pedestal being reciprocally mounted for movement through the passage along a longitudinal axis (a); and an actuator for moving the pedestal along the longitudinal axis between a low position and a high position, when the pedestal is in the low position, the flat upper surfaces of the pedestal are substantially below a rim of the container and the interior walls of the container direct the components onto the flat upper surfaces of the pedestal and when the pedestal is in the high position, a plurality of select components are on the flat upper surfaces, as the pedestal moves from the low position to the high position, a plurality of excess components are dispersed through the channels; and when the pedestal is in the high position, a plurality of select components are isolated, on the flat upper surfaces, from the other components.
Method for producing cavities having an optically transparent wall in a component using microsystems engineering, wherein the component is realized on a silicon substrate, wherein a silicon region is produced, which is surrounded on all sides by at least one optically transparent cladding layer by virtue of a buried doped region being produced in the silicon substrate, an anodization being carried out, in the course of which a buried porous region arises from the buried doped region, and by virtue of an oxidation being carried out, in the course of which the porous silicon in the buried region is oxidized and a silicon oxide layer forms on the surface of the silicon substrate, such that said silicon region lies between the oxidized porous silicon and the silicon oxide layer and is surrounded on all sides by a silicon oxide cladding layer, wherein at least one opening is produced in the cladding layer, wherein the silicon surrounded by the cladding layer is removed via the opening in the cladding layer, and wherein the cladding layer acts as an etch stop layer.
A method of welding laminated metal foils sandwiched between a pair of metal plates (12, 13) to the pair of metal plates (12, 13), the method comprising: locally pressing and crimping the laminated metal foils sandwiched between the pair of metal plates (12, 13) at a welding point in a laminating direction; welding the crimped pair of metal plates (12, 13) and laminated metal foils at the welding point; wherein in the welding, the welding point is irradiated with a laser beam to be welded; characterized in that in the welding, an irradiation condition of the laser beam is feedback-controlled based on intensity of thermal radiation light emitted from a molten pool formed by the irradiation of the laser beam; wherein in the welding, contact of the molten pool with a base on which the pair of metal plates (12, 13) and the laminated metal foils are placed is detected based on the intensity of the thermal radiation light, and when the contact of the molten pool with the base is detected, the irradiation of the molten pool with the laser beam is ended. locally pressing and crimping the laminated metal foils sandwiched between the pair of metal plates (12, 13) at a welding point in a laminating direction; welding the crimped pair of metal plates (12, 13) and laminated metal foils at the welding point; wherein in the welding, the welding point is irradiated with a laser beam to be welded; characterized in that in the welding, an irradiation condition of the laser beam is feedback-controlled based on intensity of thermal radiation light emitted from a molten pool formed by the irradiation of the laser beam; wherein in the welding, contact of the molten pool with a base on which the pair of metal plates (12, 13) and the laminated metal foils are placed is detected based on the intensity of the thermal radiation light, and when the contact of the molten pool with the base is detected, the irradiation of the molten pool with the laser beam is ended.
A trim unit (200; 200'; 200"; 440) for an electrical switch comprising a trim plate (210; 210'; 210") that presents an opening (215; 215'; 215") and a control member (220; 220'; 220") that is received in the opening (215; 215'; 215"), characterised in that the opening is an annular gap that is situated between a central portion of the trim plate and a peripheral portion of the trim plate and in that the trim plate (210; 210'; 210") is mounted on a plane front face of a backplate that includes holder means (241; 240) for holding the control member (220; 220'; 220") in the opening (215; 215'; 215").
A compound of Formula I: wherein M is H, Pd, Zn, Pt, Gd, or Yb; each R 1 is same or different and, independently, C X--(CH 2) n -YC C(R 4)CH 2, C X--(CH 2 CH 2 O) m CH 2 CH 2 --YC C(R 4)CH 2, or COOH; R 7 is C X--(CH 2) n --YC C(R 4)CH 2 or C X--(CH 2 CH 2 O) m CH 2 CH 2 -YC C(R 4)CH 2; R 2 and R 3 are fused, in each case, to form a cycloalkenyl, aryl, or heteroaryl group; X is O or NR 5; Y is O; R 5 and R 4 are independently H or C 1 -C 4 alkyl; each R 6 is same or different and, independently, H or F; n is 1-10; and m is 1-300. wherein M is H, Pd, Zn, Pt, Gd, or Yb; each R 1 is same or different and, independently, C X--(CH 2) n -YC C(R 4)CH 2, C X--(CH 2 CH 2 O) m CH 2 CH 2 --YC C(R 4)CH 2, or COOH; R 7 is C X--(CH 2) n --YC C(R 4)CH 2 or C X--(CH 2 CH 2 O) m CH 2 CH 2 -YC C(R 4)CH 2; R 2 and R 3 are fused, in each case, to form a cycloalkenyl, aryl, or heteroaryl group; X is O or NR 5; Y is O; R 5 and R 4 are independently H or C 1 -C 4 alkyl; each R 6 is same or different and, independently, H or F; n is 1-10; and m is 1-300.
A delayed release drug formulation for oral administration to deliver a drug to the colon of a subject, said formulation comprising: a core and a coating for the core, the core comprising a drug and the coating comprising an outer layer and at least one layer between the core and the outer layer selected from the group consisting of an isolation layer and an inner layer, said outer layer comprising a mixture of a first polymeric material which is susceptible to attack by colonic bacteria and a second polymeric material which has a pH threshold at pH 6 or above, said inner layer comprising a third polymeric material which is a non-ionic polymer which is soluble in intestinal fluid or gastrointestinal fluid, and at least one additive selected from a buffer agent and a base, said isolation layer comprising a non-ionic polymer which is soluble in intestinal fluid or gastrointestinal fluid, wherein the outer layer is applied directly to the inner layer or the isolation layer using a coating preparation formed by combining said first polymeric material in an aqueous medium with said second polymeric material in an organic medium. a core and a coating for the core, the core comprising a drug and the coating comprising an outer layer and at least one layer between the core and the outer layer selected from the group consisting of an isolation layer and an inner layer, said outer layer comprising a mixture of a first polymeric material which is susceptible to attack by colonic bacteria and a second polymeric material which has a pH threshold at pH 6 or above, said inner layer comprising a third polymeric material which is a non-ionic polymer which is soluble in intestinal fluid or gastrointestinal fluid, and at least one additive selected from a buffer agent and a base, said isolation layer comprising a non-ionic polymer which is soluble in intestinal fluid or gastrointestinal fluid,
Micro-mechanical timepiece part, namely escape wheel (3, 53) or escapement anchor (1, 105), comprising impulse planes (67, 121) provided to slide against corresponding contact zones of another micro-mechanical part, namely an escapement anchor or an escape wheel respectively, in a timepiece, characterised in that - the micro-mechanical part is produced from a fragile material; - said impulse planes of the micro-mechanical part are striated, the striations being straight and parallel to the sliding direction; - the striations are separated by solid intervals having a width between 0.5 and 50 micrometres; preferably between 0.5 and 25 micrometres; - in cross section, the striations have the angular shape of crenellations and the solid intervals have the angular shape of merlons; - the impulse planes each have an effective contact area corresponding to the area of the portion of the impulse plane that is occupied by the solid intervals; - the effective contact area is between 2 and 70% of the total area of the impulse plane. - the micro-mechanical part is produced from a fragile material; - said impulse planes of the micro-mechanical part are striated, the striations being straight and parallel to the sliding direction; - the striations are separated by solid intervals having a width between 0.5 and 50 micrometres; preferably between 0.5 and 25 micrometres; - in cross section, the striations have the angular shape of crenellations and the solid intervals have the angular shape of merlons; - the impulse planes each have an effective contact area corresponding to the area of the portion of the impulse plane that is occupied by the solid intervals; - the effective contact area is between 2 and 70% of the total area of the impulse plane.
Cutting device, in particular a garden cutting device, having a first and a second cutting element (12, 14) that are movable relative to one another, having a first and a second gripping element (16, 18) that are movable relative to one another, having at least one drive unit, which is provided, in at least one operating state, at least to support a movement of the second cutting element relative to the first cutting element, and having at least one driving force transmission element, which, at least in the one operating state, is operatively connected to the drive unit, characterized in that the driving force transmission element has a cable that has a loop and a knot, wherein the knot is arranged on, in particular at least partially in, a receptacle of a winch, and the loop is arranged on a lever.
Agricultural machine intended to be moved in a direction of advance in work configuration and in transport configuration and comprising a frame carrying at least a tool and a coupling head for its connection to a three point hitching device of a tractor vehicle, the coupling head comprising, on the one hand, a hitching crossbar with fasteners at its two opposite ends, intended to engage with the two lower hitching points of the three point hitching device and, on the other hand, an articulated coupling part for the said crossbar, which is rigidly fastened to the frame and receives this crossbar in a flat assembly space in which it is movable with translational and rotational guidance by means of a pivot / slide connection, the axis of the pivot being perpendicular to the plane of the assembly space, the slide being substantially rectilinear and parallel to the said plane and to the direction of advance and having opposite front and rear ends (8', 8"), machine in which the said relative rotational movements between the crossbar and the articulated coupling part are limited by stops, respectively front and rear in relation to the direction of advance, and in which the pivot is rigidly fastened to the crossbar and rests against the front end of the said slide when the said machine is subjected to a traction force in the direction of advance by means of the said crossbar, machine characterized in that the articulated coupling part of the coupling head comprises, on the one hand, a hitching means for the pivot, preferably of the type that can be retracted by rotating, locking its translation in the slide in the direction of the rear end (8") when this part is subjected to a relative displacement in the direction of advance in relation to the hitching crossbar and, on the other hand, an elastic stressing means which automatically engages the said hitching means with the said pivot when the latter is positioned in the slide beyond a given distance from the rear end (8").
The compound RK-33, or a salt, solvate, enantiomer, stereoisomer, diastereoisomer, tautomeric form or hydrate thereof, for use as a radiation dose sensitizer in a subject suffering from a proliferative disease and undergoing stereotactic ablative radiotherapy (SABR), stereotactic radiosurgery, or stereotactic body radiation therapy (SBRT).