A surgical instrument, comprising: a handle; a shaft assembly configured to be releasably coupled to the handle, wherein the shaft assembly comprises; a clamping trigger rotatably connected to the shaft assembly, wherein the clamping trigger is rotatable between a first position and a second position; a shaft comprising a longitudinal shaft axis; a shaft rotation joint configured to permit said shaft to rotate about said longitudinal shaft axis relative to said handle; an end effector comprising a proximal end effector portion, a distal end effector portion and a longitudinal end effector axis, wherein said distal end effector portion comprises a jaw assembly, wherein the clamping trigger is rotatable to open or close the jaw assembly; an articulation joint, wherein said articulation joint is distal with respect to said shaft rotation joint, wherein said articulation joint rotatably connects said proximal end effector portion to said shaft, and wherein said end effector is rotatable about an articulation axis; and an end effector rotation joint, wherein said end effector rotation joint is distal with respect to said articulation joint, and wherein said distal end effector portion is rotatable about said longitudinal end effector axis relative to said proximal end effector portion about said end effector rotation joint. a handle; a shaft assembly configured to be releasably coupled to the handle, wherein the shaft assembly comprises; a clamping trigger rotatably connected to the shaft assembly, wherein the clamping trigger is rotatable between a first position and a second position; a shaft comprising a longitudinal shaft axis; a shaft rotation joint configured to permit said shaft to rotate about said longitudinal shaft axis relative to said handle; an end effector comprising a proximal end effector portion, a distal end effector portion and a longitudinal end effector axis, wherein said distal end effector portion comprises a jaw assembly, wherein the clamping trigger is rotatable to open or close the jaw assembly; an articulation joint, wherein said articulation joint is distal with respect to said shaft rotation joint, wherein said articulation joint rotatably connects said proximal end effector portion to said shaft, and wherein said end effector is rotatable about an articulation axis; and an end effector rotation joint, wherein said end effector rotation joint is distal with respect to said articulation joint, and wherein said distal end effector portion is rotatable about said longitudinal end effector axis relative to said proximal end effector portion about said end effector rotation joint. a clamping trigger rotatably connected to the shaft assembly, wherein the clamping trigger is rotatable between a first position and a second position; a shaft comprising a longitudinal shaft axis; a shaft rotation joint configured to permit said shaft to rotate about said longitudinal shaft axis relative to said handle; an end effector comprising a proximal end effector portion, a distal end effector portion and a longitudinal end effector axis, wherein said distal end effector portion comprises a jaw assembly, wherein the clamping trigger is rotatable to open or close the jaw assembly; an articulation joint, wherein said articulation joint is distal with respect to said shaft rotation joint, wherein said articulation joint rotatably connects said proximal end effector portion to said shaft, and wherein said end effector is rotatable about an articulation axis; and an end effector rotation joint, wherein said end effector rotation joint is distal with respect to said articulation joint, and wherein said distal end effector portion is rotatable about said longitudinal end effector axis relative to said proximal end effector portion about said end effector rotation joint.