Pharmaceutical container for drug delivery, having - a barrel and a stopper, the stopper being slidably arranged within the barrel, - the stopper having a proximal end suitable for contacting a plunger rod, and a distal end suitable for contacting a pharmaceutical composition, - the stopper having a circumferential surface partially contacting an inner surface of the barrel, - the stopper having one or more annular protrusions contacting the inner surface of the barrel when the stopper moves in distal direction, - the annular protrusions each having a rising edge and a falling edge in proximal-distal direction, wherein the rising edge of the most proximal annular protrusion and the inner surface of the barrel span angle X in the distal direction, the falling edge of the most distal annular protrusion and the inner surface span an angle A in the proximal direction, and the ratio X/A is at least 1.05, wherein the container exhibits a ratio of the break loose force relative to the glide force of BLF/GF ≤ 2 during a break loose and glide force test and wherein the total glide force variation TGFV = GF max - GF min measured when the stopper is moved from start position to its end position is TGFV < 2 N, wherein the break loose and glide force test comprises - filling the containers to be tested with water for injection or demineralized water, - fixing the filled containers at room temperature in vertical orientation in a universal testing machine, - and pushing the stoppers with plungers with flat ends with a speed of 20 mm/min into the containers until an initial force of 0.25 N is reached, and - pushing the stoppers with a test speed of 100 mm/min into the containers and recording the force until a shut-off value of 35 N is reached, and the break loose force is determined as the highest force measured within the first 4 mm of stopper movement and the mean and maximum glide force values are measured within a test range starting after 4 mm of movement and ending 10 mm before reaching the distal end of the barrel, and wherein a ratio of water contact angles between the stopper's circumferential surface θ C and the barrel's inner surface θ I is θ C /θ I > 0.9. - a barrel and a stopper, the stopper being slidably arranged within the barrel, - the stopper having a proximal end suitable for contacting a plunger rod, and a distal end suitable for contacting a pharmaceutical composition, - the stopper having a circumferential surface partially contacting an inner surface of the barrel, - the stopper having one or more annular protrusions contacting the inner surface of the barrel when the stopper moves in distal direction, - the annular protrusions each having a rising edge and a falling edge in proximal-distal direction, the rising edge of the most proximal annular protrusion and the inner surface of the barrel span angle X in the distal direction, the falling edge of the most distal annular protrusion and the inner surface span an angle A in the proximal direction, and the ratio X/A is at least 1.05, wherein the container exhibits a ratio of the break loose force relative to the glide force of BLF/GF ≤ 2 during a break loose and glide force test and wherein the total glide force variation TGFV = GF max - GF min measured when the stopper is moved from start position to its end position is TGFV < 2 N, wherein the break loose and glide force test comprises - filling the containers to be tested with water for injection or demineralized water, - fixing the filled containers at room temperature in vertical orientation in a universal testing machine, - and pushing the stoppers with plungers with flat ends with a speed of 20 mm/min into the containers until an initial force of 0.25 N is reached, and - pushing the stoppers with a test speed of 100 mm/min into the containers and recording the force until a shut-off value of 35 N is reached, - filling the containers to be tested with water for injection or demineralized water, - fixing the filled containers at room temperature in vertical orientation in a universal testing machine, - and pushing the stoppers with plungers with flat ends with a speed of 20 mm/min into the containers until an initial force of 0.25 N is reached, and - pushing the stoppers with a test speed of 100 mm/min into the containers and recording the force until a shut-off value of 35 N is reached, and the break loose force is determined as the highest force measured within the first 4 mm of stopper movement and the mean and maximum glide force values are measured within a test range starting after 4 mm of movement and ending 10 mm before reaching the distal end of the barrel, and wherein a ratio of water contact angles between the stopper's circumferential surface θ C and the barrel's inner surface θ I is θ C /θ I > 0.9.