Roof system for a vehicle having a roof opening in a roof part (2,2') thereof, comprising: at least a closure which is movable between a closed position in which it closes the roof opening and an open position in which it opens the roof opening and is positioned at least partially above an adjoining roof part; a stationary guide rail at each longitudinal side of said roof opening, suitable for slidably guiding an operating mechanism that operates the closure in a longitudinal direction of the vehicle, said operating mechanism comprising: a first device including a lever for moving the rear edge of the closure towards a raised position relative to the closed position and above the adjoining roof part; a second device including a lever for moving the front edge of the closure in a vertical direction; and a guiding slide which is slidably accommodated in each guide rail and is drivable by a drive member in order to move the closure both in vertical and in horizontal direction through the first and second devices; wherein one of said levers (7;16) has, at a first end, a first pivotal connection to the closure, and, remote from the first end, spaced second and third connections (8,10) one of which connecting the respective lever at least to the guiding slide; wherein said lever is pivotally connected to a sliding member at the other of said second and third connections (8,10), said sliding member being separate from the guiding slide and being capable of sliding in the longitudinal direction of the stationary guide rail; characterised in that the sliding member is supported by the guide rail in directions perpendicularly to the longitudinal sliding direction, said sliding member being guided in a guide channel of the guide rail, which is provided with a guide flange (28, 29) having a vertical flange portion which is engaged by the sliding member near the respective second or third connection (8,10). at least a closure which is movable between a closed position in which it closes the roof opening and an open position in which it opens the roof opening and is positioned at least partially above an adjoining roof part; a stationary guide rail at each longitudinal side of said roof opening, suitable for slidably guiding an operating mechanism that operates the closure in a longitudinal direction of the vehicle, said operating mechanism comprising: a first device including a lever for moving the rear edge of the closure towards a raised position relative to the closed position and above the adjoining roof part; a second device including a lever for moving the front edge of the closure in a vertical direction; and a first device including a lever for moving the rear edge of the closure towards a raised position relative to the closed position and above the adjoining roof part; a second device including a lever for moving the front edge of the closure in a vertical direction; and a guiding slide which is slidably accommodated in each guide rail and is drivable by a drive member in order to move the closure both in vertical and in horizontal direction through the first and second devices; wherein one of said levers (7;16) has, at a first end, a first pivotal connection to the closure, and, remote from the first end, spaced second and third connections (8,10) one of which connecting the respective lever at least to the guiding slide; wherein said lever is pivotally connected to a sliding member at the other of said second and third connections (8,10), said sliding member being separate from the guiding slide and being capable of sliding in the longitudinal direction of the stationary guide rail; characterised in that the sliding member is supported by the guide rail in directions perpendicularly to the longitudinal sliding direction, said sliding member being guided in a guide channel of the guide rail, which is provided with a guide flange (28, 29) having a vertical flange portion which is engaged by the sliding member near the respective second or third connection (8,10).