An imaging system, comprising an imaging device and a controller, wherein the controller is configured to: provide a user with a preferred operational setting of the imaging device for acquiring an image; control the imaging device to acquire the image based on an operational setting, wherein the preferred operational setting is used for the image acquisition with or without being changed by the user prior to the image acquisition, receive a user input and to generate a discard information based on the user input, said discard information indicating whether or not the image generated by the imaging device is discarded by the user; and update the preferred operational setting using a machine learning algorithm based on the discard information, characterized in that the controller is configured to update the preferred operational setting further based on the operational setting used for acquiring the image, wherein the controller is configured to generate the discard information indicating that the image is discarded if after acquiring the image a setting parameter of a first group of parameters of the operational setting for a next image acquisition is changed by the user compared to the operational setting with which the image was acquired, wherein the controller is configured to generate the discard information indicating that the image is not discarded if after acquiring the image only a setting parameter of a second group of parameters of the operational setting is changed by the user compared to the operational setting with which the image was acquired, wherein the first group of parameters includes at least of one of exposure time setting, gain setting, contrast setting, and illumination light setting, wherein the second group of parameters includes at least one of a zoom setting and a stage setting, and wherein the imaging system is a microscope system. provide a user with a preferred operational setting of the imaging device for acquiring an image; control the imaging device to acquire the image based on an operational setting, wherein the preferred operational setting is used for the image acquisition with or without being changed by the user prior to the image acquisition, receive a user input and to generate a discard information based on the user input, said discard information indicating whether or not the image generated by the imaging device is discarded by the user; and update the preferred operational setting using a machine learning algorithm based on the discard information, characterized in that the controller is configured to update the preferred operational setting further based on the operational setting used for acquiring the image, wherein the controller is configured to generate the discard information indicating that the image is discarded if after acquiring the image a setting parameter of a first group of parameters of the operational setting for a next image acquisition is changed by the user compared to the operational setting with which the image was acquired, wherein the controller is configured to generate the discard information indicating that the image is not discarded if after acquiring the image only a setting parameter of a second group of parameters of the operational setting is changed by the user compared to the operational setting with which the image was acquired, wherein the first group of parameters includes at least of one of exposure time setting, gain setting, contrast setting, and illumination light setting, wherein the second group of parameters includes at least one of a zoom setting and a stage setting, and wherein the imaging system is a microscope system.