A composite comprising: a first compound comprising a first anti-tissue adhesion compound covalently bonded to a first anti-tissue adhesion support, wherein the first compound comprises (a) the reaction product between a first anti-tissue adhesion support having at least one SH group with at least one first anti-tissue adhesion compound having at least one thiol-reactive electrophilic functional group, wherein the thiol-reactive electrophilic functional group on the first anti-adhesion compound comprises an electron-deficient vinyl group, or (b) the reaction product between at least one first anti-tissue adhesion compound having at least two SH groups and a first anti-tissue adhesion support having at least one thiol-reactive electrophilic functional group, wherein the thiol-reactive electrophilic functional group on the first anti-tissue adhesion support is selected from the group consisting of acrylate, methacrylate, acrylamide and methacrylamide adduct; and a first prohealing compound, wherein the prohealing compound comprises a polysaccharide and possesses free thiol groups forming a disulfide bond with free thiol groups on the first compound in the presence of an oxidant, wherein the composite is a laminate including a first layer and a second layer, wherein the first layer comprises the first compound comprising a first anti-tissue adhesion compound covalently bonded to a first anti-tissue adhesion support, wherein the first layer has a first surface and a second surface, and the second layer comprises the first prohealing compound, wherein the second layer has a first surface and a second surface, wherein the first surface of the first layer is adjacent to the first surface of the second layer. a first compound comprising a first anti-tissue adhesion compound covalently bonded to a first anti-tissue adhesion support, wherein the first compound comprises (a) the reaction product between a first anti-tissue adhesion support having at least one SH group with at least one first anti-tissue adhesion compound having at least one thiol-reactive electrophilic functional group, wherein the thiol-reactive electrophilic functional group on the first anti-adhesion compound comprises an electron-deficient vinyl group, or (b) the reaction product between at least one first anti-tissue adhesion compound having at least two SH groups and a first anti-tissue adhesion support having at least one thiol-reactive electrophilic functional group, wherein the thiol-reactive electrophilic functional group on the first anti-tissue adhesion support is selected from the group consisting of acrylate, methacrylate, acrylamide and methacrylamide adduct; and (a) the reaction product between a first anti-tissue adhesion support having at least one SH group with at least one first anti-tissue adhesion compound having at least one thiol-reactive electrophilic functional group, wherein the thiol-reactive electrophilic functional group on the first anti-adhesion compound comprises an electron-deficient vinyl group, or (b) the reaction product between at least one first anti-tissue adhesion compound having at least two SH groups and a first anti-tissue adhesion support having at least one thiol-reactive electrophilic functional group, wherein the thiol-reactive electrophilic functional group on the first anti-tissue adhesion support is selected from the group consisting of acrylate, methacrylate, acrylamide and methacrylamide adduct; and a first prohealing compound, wherein the prohealing compound comprises a polysaccharide and possesses free thiol groups forming a disulfide bond with free thiol groups on the first compound in the presence of an oxidant,