mhurhangee/ep-ind-claims huggingface dataset:
A respiratory assistance system comprising: a respiratory assistance device comprising: a tubular body, forming a main channel, intended for being connected, through its distal end, to an airway of a patient so that the main channel connects the patient's breathing system to the outside; at least one auxiliary channel that opens into the main channel upstream of the distal end of the latter; and a tubular nozzle integrally mounted, tightly, at the proximal end of the tubular body; and a respiratory gas supply duct able to connect said tubular nozzle to a source of respiratory gas, so as to supply respiratory gas to said auxiliary channel, characterized in that said system comprises obstacle forming means, preventing assembly of a connecting member of an external medical device to said tubular nozzle, when the latter is connected to said source of respiratory gas by means of said supply duct. a respiratory assistance device comprising: a tubular body, forming a main channel, intended for being connected, through its distal end, to an airway of a patient so that the main channel connects the patient's breathing system to the outside; at least one auxiliary channel that opens into the main channel upstream of the distal end of the latter; and a tubular nozzle integrally mounted, tightly, at the proximal end of the tubular body; and a tubular body, forming a main channel, intended for being connected, through its distal end, to an airway of a patient so that the main channel connects the patient's breathing system to the outside; at least one auxiliary channel that opens into the main channel upstream of the distal end of the latter; and a tubular nozzle integrally mounted, tightly, at the proximal end of the tubular body; and a respiratory gas supply duct able to connect said tubular nozzle to a source of respiratory gas, so as to supply respiratory gas to said auxiliary channel, characterized in that said system comprises obstacle forming means, preventing assembly of a connecting member of an external medical device to said tubular nozzle, when the latter is connected to said source of respiratory gas by means of said supply duct.
Method for determining a mass (m) of an attachment which is coupled on the front side to a supporting structure of a work vehicle by means of a front power lift, wherein the power lift has at least one upper link, at least one lower link and a length-adjustable lifting arm, wherein one operative end of the lifting arm is connected in an articulated manner to the supporting structure and another operative end of the lifting arm is coupled to a link connecting point of the lower link, characterized in that the mass m of the attachment is determined in accordance with m = AD ̅ ⋅ F → Zyl ⋅ cos φ + γ + AK ̅ ⋅ F → E ⋅ sin ψ − φ AK ̅ ⋅ g ⋅ cos φ − θ depending on the following variables: - an angle ψ between the upper link and a vehicle horizontal, - an angle φ between the lower link and the vehicle horizontal, - an angle γ between a vehicle vertical and a connecting section between two operative ends (28, 30) of the lifting arm, - an angle of inclination θ of the vehicle horizontal in relation to the earth horizontal, - a section AK which represents a connection along the lower link between the supporting structure and the attachment, - a section AD which represents a connection along the lower link between the supporting structure and the link connecting point, - a force F Zyl which is effective between the two operative ends (28, 30) of the lifting arm, and - a force F E acting on a connection between upper link and attachment and effective along the upper link. - an angle ψ between the upper link and a vehicle horizontal, - an angle φ between the lower link and the vehicle horizontal, - an angle γ between a vehicle vertical and a connecting section between two operative ends (28, 30) of the lifting arm, - an angle of inclination θ of the vehicle horizontal in relation to the earth horizontal, - a section AK which represents a connection along the lower link between the supporting structure and the attachment, - a section AD which represents a connection along the lower link between the supporting structure and the link connecting point, - a force F Zyl which is effective between the two operative ends (28, 30) of the lifting arm, and - a force F E acting on a connection between upper link and attachment and effective along the upper link.
A treatment system, comprising: a hand piece having an elongate probe with a distal tip and a length, at least one infusion lumen positioned through or along the elongate probe, at least one delivery lumen slidingly positioned through or along the infusion lumen, and a liner expandably enclosing the probe such that a cryoablative fluid introduced through one or more unobstructed openings along the infusion lumen is sprayed into contact with an interior surface of the liner and coats the interior surface; a base station having a reservoir of the cryoablative fluid and a motor; and a connection having an elongate flexible body coupling the hand piece and the base station such that the hand piece is positionable independently of the base station and the reservoir, wherein the connection defines at least one fluid lumen for delivery of the cryoablative fluid from the reservoir and to the infusion lumen within the hand piece and wherein the connection further includes an actuator cable detachably coupled to the motor and to the at least one delivery lumen in the hand piece such that actuation of the motor translates the at least one delivery lumen distally or proximally relative to the at least one infusion lumen; wherein the cryoablative fluid is introduced through the delivery lumen and subsequently passed to the infusion lumen. a hand piece having an elongate probe with a distal tip and a length, at least one infusion lumen positioned through or along the elongate probe, at least one delivery lumen slidingly positioned through or along the infusion lumen, and a liner expandably enclosing the probe such that a cryoablative fluid introduced through one or more unobstructed openings along the infusion lumen is sprayed into contact with an interior surface of the liner and coats the interior surface; a base station having a reservoir of the cryoablative fluid and a motor; and a connection having an elongate flexible body coupling the hand piece and the base station such that the hand piece is positionable independently of the base station and the reservoir, wherein the connection defines at least one fluid lumen for delivery of the cryoablative fluid from the reservoir and to the infusion lumen within the hand piece and wherein the connection further includes an actuator cable detachably coupled to the motor and to the at least one delivery lumen in the hand piece such that actuation of the motor translates the at least one delivery lumen distally or proximally relative to the at least one infusion lumen; wherein the cryoablative fluid is introduced through the delivery lumen and subsequently passed to the infusion lumen.
Clamping element for connecting support tubes (12; 112) or rods of gripping and handling systems in body shell construction, wherein a middle part (14; 114) has half-shells (16a, b, c, and d; 116c and d) which are arranged rigidly relative to one another and can be closed by means of correspondingly formed, half-shell-shaped covers (20a, b, c and d; 120c, d), so that the support tubes (12; 112) or rods can be clamped between the covers and the half-shells of the middle part, wherein the middle part (14; 114) has four half-shells (16a, b, c and d; 116c, d) which are arranged in two pairs in alignment with one another and are connected by means of at least one additional connecting element (24a, b, c, d; 124a, b, c, d) which consists of a tube or rod body.
Exhaust system for an internal combustion engine, having - an exhaust path which has, at least in certain sections, two parallel exhaust lines (30, 32), specifically a main line and a secondary line, - an HC adsorber which is arranged in the secondary line and has the purpose of reversibly adsorbing unburnt hydrocarbons, - an exhaust gas catalytic converter which is arranged in the main line and has the purpose of converting at least one exhaust gas component; - an actuator means for selectively conducting an exhaust gas flow through the main line and/or through the secondary line, in each case in the direction from an inlet to an outlet of the exhaust system, - a main catalytic converter which is arranged downstream of the parallel exhaust lines (30, 32), characterized in that a junction region of the secondary line with a common exhaust line has at least one junction opening which is configured in such a way that in a position of the actuator means in which the main line and the secondary line are opened, at least a major portion of the exhaust gas flow flows through the main line. - an exhaust path which has, at least in certain sections, two parallel exhaust lines (30, 32), specifically a main line and a secondary line, - an HC adsorber which is arranged in the secondary line and has the purpose of reversibly adsorbing unburnt hydrocarbons, - an exhaust gas catalytic converter which is arranged in the main line and has the purpose of converting at least one exhaust gas component; - an actuator means for selectively conducting an exhaust gas flow through the main line and/or through the secondary line, in each case in the direction from an inlet to an outlet of the exhaust system, - a main catalytic converter which is arranged downstream of the parallel exhaust lines (30, 32),
A medicament for use in preventing and/or treating Alzheimer's disease or diabetes, or delaying senility, comprising a first active ingredient, and the first active ingredient comprises one of carrimycin, isovalerylspiramycin I, isovalerylspiramycin II and isovalerylspiramycin III, or a combination of two or three of isovalerylspiramycin I, isovalerylspiramycin II and isovalerylspiramycin III.
A mass spectrometer for analysing fragment ions, the mass spectrometer comprising: an ion source for producing fragment ions, wherein the ion source for producing fragment ions comprises an RF ion trap (102, 602); an RF multipole ion guide (104, 305, 306, 607); an ion mobility spectrometer (101, 301, 603) for receiving fragment ions produced by the ion source and for separating at least a fraction of the received fragment ions according to their ion mobility into mobility-separated fragment ions; and a system of electrodes (101, 102, 103, 104, 301, 305, 306, 602, 603, 604, 607) configured to receive DC electrical potentials to transfer at least a fraction of the mobility-separated fragment ions to a mass analyser (103, 604) for generating a mass-to-charge (m/z) spectrum exhibiting reduced spectral complexity; wherein the mass spectrometer is arranged to eject ions from the RF ion trap (102, 602), to re-trap the ejected ions within the RF multipole ion guide (104, 305, 306, 607), and subsequently to gate the re-trapped ions into the ion mobility spectrometer (101, 301, 603); characterised by: wherein the system of electrodes (101, 102, 103, 104, 301, 305, 306, 602, 603, 604, 607) is configured to receive DC electrical potentials so as to raise the potential energy level of the ions stored in the RF multipole ion guide (104, 305, 306, 607) and simultaneously to raise the DC voltage gradient established across the ion mobility spectrometer (101, 301, 603) that induces separation. an ion source for producing fragment ions, wherein the ion source for producing fragment ions comprises an RF ion trap (102, 602); an RF multipole ion guide (104, 305, 306, 607); an ion mobility spectrometer (101, 301, 603) for receiving fragment ions produced by the ion source and for separating at least a fraction of the received fragment ions according to their ion mobility into mobility-separated fragment ions; and a system of electrodes (101, 102, 103, 104, 301, 305, 306, 602, 603, 604, 607) configured to receive DC electrical potentials to transfer at least a fraction of the mobility-separated fragment ions to a mass analyser (103, 604) for generating a mass-to-charge (m/z) spectrum exhibiting reduced spectral complexity; wherein the mass spectrometer is arranged to eject ions from the RF ion trap (102, 602), to re-trap the ejected ions within the RF multipole ion guide (104, 305, 306, 607), and subsequently to gate the re-trapped ions into the ion mobility spectrometer (101, 301, 603); characterised by: wherein the system of electrodes (101, 102, 103, 104, 301, 305, 306, 602, 603, 604, 607) is configured to receive DC electrical potentials so as to raise the potential energy level of the ions stored in the RF multipole ion guide (104, 305, 306, 607) and simultaneously to raise the DC voltage gradient established across the ion mobility spectrometer (101, 301, 603) that induces separation.
An ERK inhibitor for use in treating spinal muscular atrophy associated to a deficiency in a Survival-Motor-Neuron gene, said deficiency resulting in loss of motor function, wherein said ERK inhibitor is a compound which inhibits MEK ERK1/2 signaling activity as measured by the relative amount of phosphorylated ERK proteins or Elk1 protein.
A ski boot comprising: - a cuff and a lower shell mutually coupled to define a substantially rigid support structure; - a liner designed to receive the foot of a user, said liner being positionable inside said support structure, the latter having a first end portion and a second end portion mutually slidable between at least one first initial position and at least one second operative position so as to vary the mutual distance thereof and thus the configuration of the ski boot; - a plurality of connection elements for the operative connection of said first and second end portions ( 4, 5); - a single lever selectively actuatable by the user operatively connected with said plurality of connection elements so that the action of the former allows the sliding of said first and second end portions ( 4, 5) from said at least one first initial position to said at least one second operative position; the ski boot being characterised in that each of the connection elements of said plurality comprises a pair of mutually engeagable male and female elements ( 51, 52), the female element being anchored to one of said first and second end portions ( 4, 5), the male element being operatively connected with the other of said first and second end portions ( 4, 5), a plurality of tensioners interposed between each of said male elements and said single actuation lever being further provided, so that said single actuation lever acts simultaneously on all the connection elements of said plurality. - a cuff and a lower shell mutually coupled to define a substantially rigid support structure; - a liner designed to receive the foot of a user, said liner being positionable inside said support structure, the latter having a first end portion and a second end portion mutually slidable between at least one first initial position and at least one second operative position so as to vary the mutual distance thereof and thus the configuration of the ski boot; - a plurality of connection elements for the operative connection of said first and second end portions ( 4, 5); - a single lever selectively actuatable by the user operatively connected with said plurality of connection elements so that the action of the former allows the sliding of said first and second end portions ( 4, 5) from said at least one first initial position to said at least one second operative position;
A method for manufacturing coagulated particles from a latex prepared by emulsion polymerization, comprising step of discharging the latex prepared by emulsion polymerization containing a thickener into a solution containing a coagulating agent, to coagulate the latex prepared by emulsion polymerization, wherein the thickener is contained in an amount of from 0.01 to 3.0 parts by weight, per 100 parts by weight of a polymer solid content of the latex prepared by emulsion polymerization, the thickener is a nonionic water-soluble polymer, and the latex prepared by emulsion polymerization is discharged from a nozzle such that the linear velocity of the latex prepared by emulsion polymerization at the nozzle outlet is 0.3 to 2 m/s.
An axial pump for pumping liquid metal, the axial pump comprising - an inlet for receiving liquid, - at least one rotor, the rotor comprising a rotor hub and a plurality of rotor blades positioned thereon, - a stator, comprising a stator hub and a plurality of stator vanes, and - an outlet for discharging the liquid metal, - characterised in that the inlet is defined by two axially concentric walls, the concentric walls having curved edges such that the inlet walls define an inlet entrance area which normal vector is substantially perpendicular to the axis of the axial pump, and in that the rotor blades have a tip being positioned closest to the wall opposing the rotor and whereby the ratio of the distance between the rotor axis and the rotor hub, being the rotor hub radius, to the distance between the rotor axis and the rotor blade tip, being the rotor tip radius, is larger than 0.87. - an inlet for receiving liquid, - at least one rotor, the rotor comprising a rotor hub and a plurality of rotor blades positioned thereon, - a stator, comprising a stator hub and a plurality of stator vanes, and - an outlet for discharging the liquid metal, - characterised in that the inlet is defined by two axially concentric walls, the concentric walls having curved edges such that the inlet walls define an inlet entrance area which normal vector is substantially perpendicular to the axis of the axial pump, and in that the rotor blades have a tip being positioned closest to the wall opposing the rotor and whereby the ratio of the distance between the rotor axis and the rotor hub, being the rotor hub radius, to the distance between the rotor axis and the rotor blade tip, being the rotor tip radius, is larger than 0.87. the inlet is defined by two axially concentric walls, the concentric walls having curved edges such that the inlet walls define an inlet entrance area which normal vector is substantially perpendicular to the axis of the axial pump, and in that the rotor blades have a tip being positioned closest to the wall opposing the rotor and whereby the ratio of the distance between the rotor axis and the rotor hub, being the rotor hub radius, to the distance between the rotor axis and the rotor blade tip, being the rotor tip radius, is larger than 0.87.
Medical device wherein the medical device comprises an elongated body made of a polymer material and the polymer material encloses a passive-negative MRI marker consisting of marker particles for generating an artifact in a magnetic resonance imaging process wherein the passive-negative MRI marker is located only in a central section of the medical device in a way that the passive MRI marker has a certain distance to a circumferential surface of the medical device so that a confined artefact is obtained, wherein the distance of the passive-negative MRI marker to the outer surface of the medical device is at least 0.1 mm.
A glazing panel repair device, the device comprising a coupling arranged to couple with a single pneumatic line to deliver suction and/or positive pneumatic pressure to the device from a pump arrangement remote from the device, wherein the coupling provides: i) holding suction to secure the device to the glazing panel; and ii) pressure cycling to a repair zone; wherein the device comprises a manifold or duct arrangement communicating between the coupling and i) a suction zone to apply suction to secure the device to the glazing panel and ii) the repair zone; and wherein the manifold or duct arrangement comprises separate branches (8, 9) communicating with the suction zone and the repair zone. i) holding suction to secure the device to the glazing panel; and ii) pressure cycling to a repair zone;
A light amplifying device (50, 51) comprising: a seed light source configured to emit a pulsed seed beam; an excitation light source (3, 9A, 9B) configured to emit an excitation beam; a light amplifying fiber (1, 8) configured to amplify the seed beam with the excitation beam; and a controller configured to control light beams emitted from the seed light source and the excitation light source, wherein the controller is configured to cause the seed light source to emit the seed beam in an emission period in which the light amplifying fiber outputs the amplified light beam, to cause the excitation light source to emit the excitation beam having first-level power in a non-emission period immediately before the emission period, and to change the power of the excitation beam emitted from the excitation light source to a second level higher than the first level at a beginning of the emission period, characterised in that the controller is further configured to increase the power of the excitation beam emitted from the excitation light source to a third level higher than the second level after starting of the emission period, and to decrease gradually the power of the excitation beam from the third level to the second level. a seed light source configured to emit a pulsed seed beam; an excitation light source (3, 9A, 9B) configured to emit an excitation beam; a light amplifying fiber (1, 8) configured to amplify the seed beam with the excitation beam; and a controller configured to control light beams emitted from the seed light source and the excitation light source, wherein the controller is configured to cause the seed light source to emit the seed beam in an emission period in which the light amplifying fiber outputs the amplified light beam, to cause the excitation light source to emit the excitation beam having first-level power in a non-emission period immediately before the emission period, and to change the power of the excitation beam emitted from the excitation light source to a second level higher than the first level at a beginning of the emission period, characterised in that the controller is further configured to increase the power of the excitation beam emitted from the excitation light source to a third level higher than the second level after starting of the emission period, and to decrease gradually the power of the excitation beam from the third level to the second level.
A suspension of gas-filled microvesicles comprising a physiologically acceptable gas with a stabilizing envelope, said envelope comprising: a) a phospholipid b) from 1% to 8% by moles of a first pegylated phospholipid comprising a reactive moiety, at least a portion of said first pegylated phospholipid being bound to a ligand through said reactive moiety; and c) from 1% to 12% by moles of a second pegylated phospholipid; said suspension comprising less than 40% by moles of said ligand, either in free form or bound to said pegylated phospholipid, with respect to the molar amount of the pegylated phospholipid comprising said ligand in the envelope. a) a phospholipid b) from 1% to 8% by moles of a first pegylated phospholipid comprising a reactive moiety, at least a portion of said first pegylated phospholipid being bound to a ligand through said reactive moiety; and c) from 1% to 12% by moles of a second pegylated phospholipid;