Sealing arrangement, comprising: - a first and a second machine part (12, 14), which are arranged at a distance from one another to form a sealing gap and can be moved relative to one another about a movement axis; - a sealing element designed as a radial shaft sealing ring having a base portion which is arranged to be held on a sealing holding structure, in particular in a holding groove, of one of the two machine parts (12, 14), and - comprising a sealing head, a sealing portion of which rests against a sealing surface of the other machine part (12, 14) in each case in a dynamically sealing manner in order to seal a high-pressure side H of the sealing gap, which side can be pressurized with a fluid, against a low-pressure side N of the sealing gap, wherein the sealing portion comprises an end face having a convex cross section and comprises a tread extending away from the sealing head at the end face, wherein the tread has a continuous tread surface which rests against the sealing surface, wherein the sealing head and the base portion are connected to one another via an elastically deformable connection portion of the sealing element, which connection portion has a non-linear U-shaped cross-sectional profile at least in portions, wherein the connection portion has a first and a second leg (36, 38) which extend parallel or substantially parallel to the sealing surface and which are connected to one another via a back portion, wherein the two legs (36, 38) each have an angled end piece which extends in a direction that is radial with respect to the movement axis, wherein the end piece of one leg is integrally formed on the center of the sealing head and the end piece of the other leg is integrally formed on the base portion, wherein a free space is formed between the two legs (36, 38) of the connection portion which surrounds the sealing head around the circumference and which is directly delimited in the radial direction solely by the two legs (36, 38) of the connection portion, wherein the free space is fluidically connected to the high-pressure side H of the sealing arrangement and wherein the connection portion has a plurality of material-weakened regions in the radial direction at the level of the back portion 40, which regions are arranged one behind the other in the circumferential direction of the sealing element, preferably regularly, at a distance from one another. - a first and a second machine part (12, 14), which are arranged at a distance from one another to form a sealing gap and can be moved relative to one another about a movement axis; - a sealing element designed as a radial shaft sealing ring having a base portion which is arranged to be held on a sealing holding structure, in particular in a holding groove, of one of the two machine parts (12, 14), and - comprising a sealing head, a sealing portion of which rests against a sealing surface of the other machine part (12, 14) in each case in a dynamically sealing manner in order to seal a high-pressure side H of the sealing gap, which side can be pressurized with a fluid, against a low-pressure side N of the sealing gap, wherein the sealing portion comprises an end face having a convex cross section and comprises a tread extending away from the sealing head at the end face, wherein the tread has a continuous tread surface which rests against the sealing surface, wherein the sealing head and the base portion are connected to one another via an elastically deformable connection portion of the sealing element, which connection portion has a non-linear U-shaped cross-sectional profile at least in portions, wherein the connection portion has a first and a second leg (36, 38) which extend parallel or substantially parallel to the sealing surface and which are connected to one another via a back portion, wherein the two legs (36, 38) each have an angled end piece which extends in a direction that is radial with respect to the movement axis, wherein the end piece of one leg is integrally formed on the center of the sealing head and the end piece of the other leg is integrally formed on the base portion, wherein a free space is formed between the two legs (36, 38) of the connection portion which surrounds the sealing head around the circumference and which is directly delimited in the radial direction solely by the two legs (36, 38) of the connection portion, wherein the free space is fluidically connected to the high-pressure side H of the sealing arrangement and wherein the connection portion has a plurality of material-weakened regions in the radial direction at the level of the back portion 40, which regions are arranged one behind the other in the circumferential direction of the sealing element, preferably regularly, at a distance from one another.