A system comprising: a memory storing one or more images of a patient and one or more software applications; a display configured to present the one or more images of a patient; a user interface adapted to be presented on the display in combination with the one or more images of a patient enabling the identification of one or more image locations illustrating the effects of chronic obstructive pulmonary disease (COPD); an extended working channel navigable to one or more actual locations within a patient corresponding to the one or more image locations; an electromagnetic field generator; a first sensor associated with the extended working channel, the first sensor configured to detect a field produced by the electromagnetic field generator, wherein the detected field enables determination of the location of the first sensor in the electromagnetic field; a processor, configured to execute one of the one or more software applications to register the one or more images of a patient with the determined location of the first sensor such that the determined location of the first sensor is presented on the user interface; and a catheter (100a, 100b, 100c), extendible through the extended working channel, and characterised in that the catheter is configured to evacuate air from within a portion of a patient's lungs including the one or more actual locations within a patient corresponding to the one or more image locations illustrating the effects of COPD to temporarily isolate the portion of the lungs including the one or more actual locations in order to predict a clinical consequence of permanently isolating the portion of the lungs including the one or more actual locations. a memory storing one or more images of a patient and one or more software applications; a display configured to present the one or more images of a patient; a user interface adapted to be presented on the display in combination with the one or more images of a patient enabling the identification of one or more image locations illustrating the effects of chronic obstructive pulmonary disease (COPD); an extended working channel navigable to one or more actual locations within a patient corresponding to the one or more image locations; an electromagnetic field generator; a first sensor associated with the extended working channel, the first sensor configured to detect a field produced by the electromagnetic field generator, wherein the detected field enables determination of the location of the first sensor in the electromagnetic field; a processor, configured to execute one of the one or more software applications to register the one or more images of a patient with the determined location of the first sensor such that the determined location of the first sensor is presented on the user interface; and a catheter (100a, 100b, 100c), extendible through the extended working channel, and characterised in that the catheter is configured to evacuate air from within a portion of a patient's lungs including the one or more actual locations within a patient corresponding to the one or more image locations illustrating the effects of COPD to temporarily isolate the portion of the lungs including the one or more actual locations in order to predict a clinical consequence of permanently isolating the portion of the lungs including the one or more actual locations.