mhurhangee/ep-ind-claims huggingface dataset:
A sulfated cellulose hydrate membrane comprising a crosslinked cellulose hydrate matrix with pores which extend from one main surface to another main surface of the membrane, wherein the cellulose hydrate membrane has sulfate ligands on its inner and outer surfaces for the adsorptive substance separation, and wherein the degree of sulfation of the cellulose hydrate matrix is 15% by weight or more.
A motor tricycle having a vehicle body, a single front wheel attached to the vehicle body and steered by a handlebar, a pair of left and right rear wheels driven in the rear of said vehicle body, a pair of left and right drive means for driving said left and right rear wheels respectively, a steering angle detecting means for detecting a steering angle (θ) of said handlebar and a speed detecting means for detecting a travel speed of said vehicle body, wherein an inner wheel is defined as one of the left and right rear wheels, that is, one rear wheel (14L, 14R) in an inner position relative to a curve, and wherein an outer wheel is defined as the other rear wheel (14L, 14R) in an outer position relative to said curve; wherein a rotation speed ratio is defined as the rotations of the outer wheel per one rotation of the inner wheel; wherein the motor tricycle further comprises a control unit adapted to perform, when said travel speed is not less than a predetermined speed, and said steering angle is not less than a predetermined angle, addition of an additional rotation speed ratio meeting the thus travel speed and the thus steering angle (θ) to an outer-wheel necessary rotation speed ratio being a rotation speed ratio obtained in accordance with the handlebar steering angle (θ) detected by said steering angle detecting means on the assumption that no skid occurs between each of said left and right rear wheels and a road surface at the time when said vehicle body turns the curve by the turning operation of said handlebar, and then to permit said outer wheel to be driven by said drive means (13L, 13R) with a rotation speed ratio resulting from the addition.
An oven comprising an exterior body, a cooking cavity wherein the cooking process is performed, a heater that provides foodstuffs placed into the cooking cavity to be cooked, a cooling fan arranged between the exterior body and the cooking cavity, that provides air circulation around the cooking cavity, and a control unit that performs the cooking process in at least three phases being the first phase, the second phase and the third phase from the start to end of the cooking, in the first phase at a first temperature defined by the user at the start of cooking process for a first phase duration, in the second phase, at a second temperature lower than the temperature defined by the user for a second phase duration and in the third phase at a third temperature higher than the temperature in the first or second phase for a third phase duration, characterized by the cooling fan, the activation of which is delayed by the control unit until the end of the first phase and that is activated in the second phase.
Apparatus for actuating a hydraulic piston for an electrically actuable clutch, the apparatus having: an electric motor; a force transmission arrangement, for transmitting a force which is brought about by the electric motor as a linearly acting force for actuating the hydraulic piston; the force transmission arrangement having: a drive wheel segment with a toothing system which is arranged on its circumference, and with a first pin and second pins which are spaced apart from the first pin, a guide arrangement which has a first and a second slot (19, 21), the first pin being guided in the first slot and the second pin being guided in the second slot, in such a way that the guide arrangement is moved linearly during rotation of the drive wheel segment, characterized in that the drive wheel segment is mounted such that it can be rotated about a first pin, and in that the first and the second slot are arranged at a right angle with respect to one another. an electric motor; a force transmission arrangement, for transmitting a force which is brought about by the electric motor as a linearly acting force for actuating the hydraulic piston; the force transmission arrangement having: a drive wheel segment with a toothing system which is arranged on its circumference, and with a first pin and second pins which are spaced apart from the first pin, a guide arrangement which has a first and a second slot (19, 21), a drive wheel segment with a toothing system which is arranged on its circumference, and with a first pin and second pins which are spaced apart from the first pin, a guide arrangement which has a first and a second slot (19, 21), the first pin being guided in the first slot and the second pin being guided in the second slot, in such a way that the guide arrangement is moved linearly during rotation of the drive wheel segment, characterized in that the drive wheel segment is mounted such that it can be rotated about a first pin, and in that the first and the second slot are arranged at a right angle with respect to one another.
A fiber-reinforced concrete containing at least one cement material, at least one aggregate composition and at least one superplasticizer, wherein the aggregate composition comprises a mixture of barite, colemanite, and magnetite.
A connecting means for connecting at least one first element to a base element, comprising: - a body that can be inserted with the lower region into an indentation in the base element and has two oppositely positioned protruding connection parts in the lower region; - whose lower and upper regions are separated by a middle region, said middle region having a circular cross-section; - said connecting means being provided for connecting said base element with said at least one first element by rotating by a defined angle; - wherein said upper region has two oppositely positioned protruding connection parts; - wherein, because of the rotation, said protruding connection parts of the lower region engage by positive locking in lateral recesses of the indentation in the base element, and at least one connection part of the upper region engages in a recess, which is preferably complementarily shaped, of said at least one first element, - wherein said connecting means is equipped with a locking means in order to complicate or prevent rotation of the connecting means beyond the defined angle characterized in that said protruding connection parts of the upper region are designed in the form of a trapezoid prism and arranged orthogonally to the two protruding connection parts in the lower region, wherein said upper region has a width that is the same or smaller than the circular cross-section of said middle region. - a body that can be inserted with the lower region into an indentation in the base element and has two oppositely positioned protruding connection parts in the lower region; - whose lower and upper regions are separated by a middle region, said middle region having a circular cross-section; - said connecting means being provided for connecting said base element with said at least one first element by rotating by a defined angle; - wherein said upper region has two oppositely positioned protruding connection parts; - wherein, because of the rotation, said protruding connection parts of the lower region engage by positive locking in lateral recesses of the indentation in the base element, and at least one connection part of the upper region engages in a recess, which is preferably complementarily shaped, of said at least one first element, - wherein said connecting means is equipped with a locking means in order to complicate or prevent rotation of the connecting means beyond the defined angle
A stable formulation of 15 mg/ml of an anti-CD 19 antibody conjugated to monomethylauristatin F (MMAF), in 10mM potassium phosphate buffer, wherein the anti-CD19 antibody is a humanized IgG1 antibody comprising a full length light chain having a variable region of SEQ ID NO:1 and a full length heavy chain having a variable region of SEQ ID NO:2, wherein the anti-CD 19 antibody is conjugated to maleimidocaproyl monomethyl auristatin F, the formulation comprising a surfactant and a bulking agent, wherein the potassium phosphate buffer has a pH value between 5.0 and 7.0, wherein the surfactant is polysorbate 80 at a concentration 0.02% w/v, and wherein the bulking agent is sucrose at a concentration of 6% w/v.
An effervescent composition, administered orally following its dispersion in water, characterized by comprising particles containing vildagliptin or a pharmaceutically acceptable salt of vildagliptin, an acid, and a carbonate, and an air- and humidity-barrier package into which said particles are filled. particles containing vildagliptin or a pharmaceutically acceptable salt of vildagliptin, an acid, and a carbonate, and an air- and humidity-barrier package into which said particles are filled.
Assembly system (1, 31) including first and second parts (3, 5, 33, 35') each including a blind recess (2, 4) and at least a third part (7, 35, 37', 37) including a through hole, characterized in that the assembly system (1, 31) further includes a permanent securing device (9, 39) including a pin (11, 41) mounted in the through hole of the at least one third part, the pin (11, 41) including, at a first end, a first means of locking in said blind recess of one of the first and second parts (3, 5, 33, 35') characterized in that it includes a socket (13, 43) whose external wall includes a second means of locking in said blind recess of the other of the first and second parts (3, 5, 33, 35') and whose internal wall is welded to the second end of the pin (11, 41) in order to join the first, second and at least one third parts (3, 5, 33, 35', 7, 35, 37', 37) to each other with no plastic deformation of the first and second parts (3, 5, 33, 35').
Process for producing metallised metal-ceramic substrates as circuit carriers, in particular for power semiconductor components or power semiconductor modules, comprising the following process steps: applying an aluminium-magnesium layer or an aluminium silicon layer to a copper plate or copper foil, wherein the aluminium-magnesium layer or aluminium-silicon layer is applied under pressure to the copper plate or foil, placing the copper plate or foil with the coated side on a ceramic substrate, heating the ceramic substrate with the placed copper plate or foil to a process temperature so that the copper plate or foil adhesively bonds to the ceramic substrate, and cooling the composite of ceramic substrate and copper plate or foil to room temperature, wherein the copper plate or foil is structured to form conductor tracks for the circuit carrier before being placed on the ceramic substrate or is structured in conjunction with the ceramic substrate. applying an aluminium-magnesium layer or an aluminium silicon layer to a copper plate or copper foil, wherein the aluminium-magnesium layer or aluminium-silicon layer is applied under pressure to the copper plate or foil, placing the copper plate or foil with the coated side on a ceramic substrate, heating the ceramic substrate with the placed copper plate or foil to a process temperature so that the copper plate or foil adhesively bonds to the ceramic substrate, and cooling the composite of ceramic substrate and copper plate or foil to room temperature, wherein the copper plate or foil is structured to form conductor tracks for the circuit carrier before being placed on the ceramic substrate or is structured in conjunction with the ceramic substrate.
Drug delivery device comprising: a housing body; a piston rod configured to rotate in a first direction during dose dispensing under a driving torque; and a threaded insert, wherein the piston rod is in threaded engagement with the threaded insert such that during dose dispensing, the piston rod displaces axially in a distal direction relative to the threaded insert, characterized in that the threaded insert is movable relative to a stop provided in the housing body and that a resilient means is provided to bias the threaded insert against the stop so that rotation of the piston rod causes the threaded insert to move away from the stop in response to reaction forces acting on the piston rod in a proximal direction when the reaction forces exceed the biasing force of the resilient means. a housing body; a piston rod configured to rotate in a first direction during dose dispensing under a driving torque; and a threaded insert, wherein the piston rod is in threaded engagement with the threaded insert such that during dose dispensing, the piston rod displaces axially in a distal direction relative to the threaded insert, characterized in that the threaded insert is movable relative to a stop provided in the housing body and that a resilient means is provided to bias the threaded insert against the stop so that rotation of the piston rod causes the threaded insert to move away from the stop in response to reaction forces acting on the piston rod in a proximal direction when the reaction forces exceed the biasing force of the resilient means.
A method for preparing a composition comprising monomeric calicheamicin derivative/antibody conjugates with reduced low conjugated fraction below 10 percent having the formula, Pr(-X-S-S-W) m, wherein: Pr is an antibody, X is a hydrolyzable linker that is capable of releasing the calicheamicin derivative from the conjugate after binding and entry into target cells, W is a calicheamicin; m is the average loading for a purified conjugation product such that the cytotoxic drug constitutes 4 - 10% of the conjugate by weight; and (-X-S-S-W) m is a calicheamicin derivative, said method comprising the steps of: adding the calicheamicin derivative to the antibody wherein the calicheamicin derivative is 4.5 - 11% by weight of the antibody; incubating the calicheamicin derivative and the antibody in a non-nucleophilic, protein-compatible, buffered solution having a pH in the range from about 8 to 9 to produce a composition comprising monomeric cytotoxic drug/carrier conjugate, wherein the solution further comprises (a) ethanol, and (b) an additive comprising at least one C 6 -C 18 carboxylic acid or its salt, selected from: decanoate, 100 mM nanonoate, 20 mM undecanoate, 5 mM dodecanoate, and wherein the incubation is conducted at a temperature ranging from about 30 °C to about 35 °C for a period of time ranging from about 15 minutes to 24 hours; and subjecting the composition produced in step to a chromatographic separation process to separate monomeric cytotoxic calicheamicin derivative/antibody conjugates with a loading in the range of 4 - 10% by weight cytotoxic drug and with low conjugated fraction below 10 percent from unconjugated antibody, calicheamicin derivative, and aggregated conjugates. Pr is an antibody, X is a hydrolyzable linker that is capable of releasing the calicheamicin derivative from the conjugate after binding and entry into target cells, W is a calicheamicin; m is the average loading for a purified conjugation product such that the cytotoxic drug constitutes 4 - 10% of the conjugate by weight; and (-X-S-S-W) m is a calicheamicin derivative, adding the calicheamicin derivative to the antibody wherein the calicheamicin derivative is 4.5 - 11% by weight of the antibody; incubating the calicheamicin derivative and the antibody in a non-nucleophilic, protein-compatible, buffered solution having a pH in the range from about 8 to 9 to produce a composition comprising monomeric cytotoxic drug/carrier conjugate, wherein the solution further comprises (a) ethanol, and (b) an additive comprising at least one C 6 -C 18 carboxylic acid or its salt, selected from: decanoate, 100 mM nanonoate, 20 mM undecanoate, 5 mM dodecanoate, and wherein the incubation is conducted at a temperature ranging from about 30 °C to about 35 °C for a period of time ranging from about 15 minutes to 24 hours; and subjecting the composition produced in step to a chromatographic separation process to separate monomeric cytotoxic calicheamicin derivative/antibody conjugates with a loading in the range of 4 - 10% by weight cytotoxic drug and with low conjugated fraction below 10 percent from unconjugated antibody, calicheamicin derivative, and aggregated conjugates.
An antenna device (10C-F) comprising a plurality of antennas, wherein: the antennas include a plurality of first antennas which form a first array and a plurality of second antennas which form a second array; the first antennas include two first predetermined antennas; a longitudinal direction of one of the first predetermined antennas and another longitudinal direction of a remaining one of the first predetermined antennas intersect with each other and define a horizontal plane; each of the first antennas mainly radiates a horizontally polarized wave which is in parallel to the horizontal plane; each of the second antennas mainly radiates a vertically polarized wave which is perpendicular to the horizontal plane; the second antennas include two second predetermined antennas; the two first predetermined antennas are arranged along a first line; the two second predetermined antennas are arranged along a second line; and when the first line and the second line are projected onto the horizontal plane along a direction perpendicular to the horizontal plane, the first line and the second line intersect with each other, characterized in that each of the first antennas is an antenna which has a split-ring resonance structure, and each of the second antennas is an antenna which has a split-ring resonance structure. the antennas include a plurality of first antennas which form a first array and a plurality of second antennas which form a second array; the first antennas include two first predetermined antennas; a longitudinal direction of one of the first predetermined antennas and another longitudinal direction of a remaining one of the first predetermined antennas intersect with each other and define a horizontal plane; each of the first antennas mainly radiates a horizontally polarized wave which is in parallel to the horizontal plane; each of the second antennas mainly radiates a vertically polarized wave which is perpendicular to the horizontal plane; the second antennas include two second predetermined antennas; the two first predetermined antennas are arranged along a first line; the two second predetermined antennas are arranged along a second line; and when the first line and the second line are projected onto the horizontal plane along a direction perpendicular to the horizontal plane, the first line and the second line intersect with each other, characterized in that each of the first antennas is an antenna which has a split-ring resonance structure, and each of the second antennas is an antenna which has a split-ring resonance structure.
A fitting part for a window, a door or the like with a holding element for holding the fitting part at a profile groove having an undercut, consisting of a clamping piece, a screw and a spring element, wherein the screw with its head is held on a cover rail of the fitting part and a shank of the screw passes through the cover rail and on its free end is screwed to the clamping piece, which limited by an at least initially sluggish threaded connection is rotatable with the screw and is designed narrower in an initial rotational position and wider in a final rotational position directed transversely thereto, than a clear opening width between the shoulders of the profile groove pointing towards the center of the groove, wherein the spring element designed as a compression spring is arranged between the cover rail and the clamping piece and surrounds the shank, wherein the spring element consists of at least one leaf spring with a largely planar base part and ends angled away from said base part on two opposite sides in the direction towards the cover rail, wherein the leaf spring has a stop for the clamping piece in the initial rotational position, characterized in that the angled ends correspond in width to the clear opening width between the shoulders of the profile groove pointing toward the center of the groove, so that in the mounted state a rotation of the spring element is prevented in the profile groove and that the leaf spring has the stop on an outer edge of the base part, close to an angled end.
A steam generator adapted for use in a steam convection oven, comprising a cylindrical steam generation vessel having a vertical steam generation portion formed to store an amount of water for generation of steam and a steam passage formed on the upper end of the steam generation portion for spouting steam generated in the steam generation portion, a heater element disposed in the interior of the steam generation portion, an induction heating coil wound around the periphery of the steam generation portion for energizing the heater element, wherein the heater element is energized by activation of the induction heating coil so that the steam is generated by boiling of the water in the steam generation portion and spouts upward from the steam passage, characterized in that a steam discharge duct is mounted on the upper end of the steam passage for receiving the steam spouting upward from the steam passage to discharge it in a lateral direction into the interior of a cooking chamber of a steam convection oven such that drops of hot water adhered to a ceiling surface of the discharge duct fall and circulate into the steam generation portion, and in that intercept means is provided for receiving drops of hot water jumping from the steam generation portion into the steam passage to spout only the steam upward and for permitting the drops of hot water falling from the steam discharge duct therethrough to be circulated into the steam generation portion.