A pericardium puncture needle assembly, comprising an outer sheath and a guide wire, wherein the guide wire can slide in the outer sheath, and the guide wire is made of a high elastic material; the guide wire comprises a distal end bent section, the distal end bent section is formed by bending the guide wire and has a preset bent shape, and the distal end bent section is adapted to regain the preset bent shape from a straightened state, and its tip end part is of a sharp tip structure; the sharp tip structure is provided with a distal end and a proximal end, the distal end of the sharp tip structure is provided with a sharp tip end for puncturing, and within a length not larger than 3 mm of the sharp tip structure, the rotation angle of the sharp tip end relative to the proximal end of the sharp tip structure is at least 90 degree; wherein the puncturing direction of the guide wire is located in a plane defined by the normal direction of the needle point plane of the outer sheath and the axial line of the outer sheath; characterized in that: the guide wire comprises a proximal end bent section, and the proximal end of the outer sheath comprises a proximal bent section; or the guide wire comprises a proximal end bent section, the outer sheath is further provided with an inner sheath, and the proximal end of the inner sheath comprises a proximal end bent section, wherein the curvature radius of the proximal end bent section of the guide wire is selected such that within a length range of not larger than 20mm, the rotation angle of the proximal end bent section of the guide wire is larger than 15 degree; the curvature radius of the proximal end bent section of the inner sheath is selected such that within a length range of not larger than 20mm, the rotation angle of the proximal end bent section of the inner sheath is larger than 45 degree. wherein the puncturing direction of the guide wire is located in a plane defined by the normal direction of the needle point plane of the outer sheath and the axial line of the outer sheath; characterized in that: the guide wire comprises a proximal end bent section, and the proximal end of the outer sheath comprises a proximal bent section; or the guide wire comprises a proximal end bent section, the outer sheath is further provided with an inner sheath, and the proximal end of the inner sheath comprises a proximal end bent section, wherein the curvature radius of the proximal end bent section of the guide wire is selected such that within a length range of not larger than 20mm, the rotation angle of the proximal end bent section of the guide wire is larger than 15 degree; the curvature radius of the proximal end bent section of the inner sheath is selected such that within a length range of not larger than 20mm, the rotation angle of the proximal end bent section of the inner sheath is larger than 45 degree. the guide wire comprises a proximal end bent section, and the proximal end of the outer sheath comprises a proximal bent section; or the guide wire comprises a proximal end bent section, the outer sheath is further provided with an inner sheath, and the proximal end of the inner sheath comprises a proximal end bent section, wherein the curvature radius of the proximal end bent section of the guide wire is selected such that within a length range of not larger than 20mm, the rotation angle of the proximal end bent section of the guide wire is larger than 15 degree; the curvature radius of the proximal end bent section of the inner sheath is selected such that within a length range of not larger than 20mm, the rotation angle of the proximal end bent section of the inner sheath is larger than 45 degree.