A method for optimizing a neighbor relation, comprising: determining, by a centralized device, to-be-processed neighboring cells according to a preset rule; generating, by the centralized device, an optimization suggestion according to the determined to-be-processed neighboring cells; and delivering, by the centralized device, the optimization suggestion to a radio network controller RNC, so that the RNC optimizes the to-be-processed neighboring cells according to the optimization suggestion, wherein the determining, by a centralized device, to-be-processed neighboring cells according to a preset rule comprises: determining, by the centralized device, whether a count value reaches a preset neighboring cell priority optimization period; if it is determined that the count value reaches the neighboring cell priority optimization period, sorting, by the centralized device, neighboring cells of a same type according to a quantity of handover success times of handovers to each cell of the neighboring cells of the same type, and acquiring at least one neighboring cell queue after sorting, wherein the neighboring cells of the same type are Universal Mobile Telecommunications System, UMTS, intra-frequency cells, UMTS inter-frequency cells, or Global System for Mobile Communications, GSM, cells; and selecting, by the centralized device, K i neighboring cells from each of the at least one neighboring cell queue according to a preset proportion threshold a and according to a sorting sequence as the to-be-processed neighboring cells, wherein K i = a× M i, K i indicates a quantity of neighboring cells selected from an i th neighboring cell queue, M i indicates a quantity of neighboring cells comprised in the i th neighboring cell queue, and i is an integer greater than or equal to 1, and less than or equal to 3. determining, by a centralized device, to-be-processed neighboring cells according to a preset rule; generating, by the centralized device, an optimization suggestion according to the determined to-be-processed neighboring cells; and delivering, by the centralized device, the optimization suggestion to a radio network controller RNC, so that the RNC optimizes the to-be-processed neighboring cells according to the optimization suggestion, wherein the determining, by a centralized device, to-be-processed neighboring cells according to a preset rule comprises: determining, by the centralized device, whether a count value reaches a preset neighboring cell priority optimization period; if it is determined that the count value reaches the neighboring cell priority optimization period, sorting, by the centralized device, neighboring cells of a same type according to a quantity of handover success times of handovers to each cell of the neighboring cells of the same type, and acquiring at least one neighboring cell queue after sorting, wherein the neighboring cells of the same type are Universal Mobile Telecommunications System, UMTS, intra-frequency cells, UMTS inter-frequency cells, or Global System for Mobile Communications, GSM, cells; and selecting, by the centralized device, K i neighboring cells from each of the at least one neighboring cell queue according to a preset proportion threshold a and according to a sorting sequence as the to-be-processed neighboring cells, wherein K i = a× M i, K i indicates a quantity of neighboring cells selected from an i th neighboring cell queue, M i indicates a quantity of neighboring cells comprised in the i th neighboring cell queue, and i is an integer greater than or equal to 1, and less than or equal to 3. determining, by the centralized device, whether a count value reaches a preset neighboring cell priority optimization period; if it is determined that the count value reaches the neighboring cell priority optimization period, sorting, by the centralized device, neighboring cells of a same type according to a quantity of handover success times of handovers to each cell of the neighboring cells of the same type, and acquiring at least one neighboring cell queue after sorting, wherein the neighboring cells of the same type are Universal Mobile Telecommunications System, UMTS, intra-frequency cells, UMTS inter-frequency cells, or Global System for Mobile Communications, GSM, cells; and selecting, by the centralized device, K i neighboring cells from each of the at least one neighboring cell queue according to a preset proportion threshold a and according to a sorting sequence as the to-be-processed neighboring cells, wherein K i = a× M i, K i indicates a quantity of neighboring cells selected from an i th neighboring cell queue, M i indicates a quantity of neighboring cells comprised in the i th neighboring cell queue, and i is an integer greater than or equal to 1, and less than or equal to 3.