An acoustic line tracing system for tracing a fluid transfer system tubing line, the tracing system comprising: a first acoustic receiver operably connectable to the tubing line and configured to receive a vibratory signal, the first acoustic receiver including: a first vibration sensor disposed to contact the tubing line, said first vibration sensor being configured for detecting vibration of the surface of the tubing line caused by the vibratory signal; a signal transmitter operatively contacting the tubing set and electrically coupled with said first acoustic receiver, said signal transmitter configured for generating acoustic vibrations in the tubing line when said first vibration sensor detects a vibratory signal; and a second acoustic receiver connectable to the tubing line and configured for receiving the acoustic vibrations generated by said signal transmitter, said second acoustic receiver including: a second vibration sensor disposed to contact the tubing line, said second vibration sensor being configured for detecting vibrations in the surface of the tubing line caused by the acoustic vibrations; and an indicator producing at least one of an audio and a visual cue when said second vibration sensor detects the vibratory signal; wherein the first acoustic receiver is upstream from the infusion pump and the signal transmitter is downstream from the infusion pump for reducing dampening of the vibrator signal by the infusion pump. a first acoustic receiver operably connectable to the tubing line and configured to receive a vibratory signal, the first acoustic receiver including: a first vibration sensor disposed to contact the tubing line, said first vibration sensor being configured for detecting vibration of the surface of the tubing line caused by the vibratory signal; a signal transmitter operatively contacting the tubing set and electrically coupled with said first acoustic receiver, said signal transmitter configured for generating acoustic vibrations in the tubing line when said first vibration sensor detects a vibratory signal; and a second acoustic receiver connectable to the tubing line and configured for receiving the acoustic vibrations generated by said signal transmitter, said second acoustic receiver including: a second vibration sensor disposed to contact the tubing line, said second vibration sensor being configured for detecting vibrations in the surface of the tubing line caused by the acoustic vibrations; and an indicator producing at least one of an audio and a visual cue when said second vibration sensor detects the vibratory signal; wherein the first acoustic receiver is upstream from the infusion pump and the signal transmitter is downstream from the infusion pump for reducing dampening of the vibrator signal by the infusion pump. a second vibration sensor disposed to contact the tubing line, said second vibration sensor being configured for detecting vibrations in the surface of the tubing line caused by the acoustic vibrations; and an indicator producing at least one of an audio and a visual cue when said second vibration sensor detects the vibratory signal; wherein the first acoustic receiver is upstream from the infusion pump and the signal transmitter is downstream from the infusion pump for reducing dampening of the vibrator signal by the infusion pump.