A method for estimating load weights for an implement of a work vehicle, the method comprising: controlling, with one or more computing devices, movement of a boom of the work vehicle such that the boom is moved across a plurality of overlapping measurement regions defined along an angular travel range of the boom, each measurement region being overlapped by at least one adjacent measurement region of the plurality of overlapping measurement regions across the angular travel range; receiving, with the one or more computing devices, load-related data associated with a load weight for the implement as the boom is moved across the plurality of overlapping measurement regions; determining, with the one or more computing devices, a region load weight for at least one measurement region of the plurality of overlapping measurement regions based on the load-related data; and calculating, with the one or more computing devices, a final load weight for the implement based on the region load weight for the at least one measurement region; the method being characterized in that it further comprises: receiving operator-initiated control commands associated with controlling an operation of at least one component of the work vehicle as the boom is moved across the plurality of overlapping measurement regions; identifying a first group of measurement regions of the plurality of overlapping measurement regions across which a variation in the operator-initiated control commands is less than a variation threshold; and identifying at least one second measurement region of the plurality of overlapping measurement regions across which the variation in the operator-initiated control commands exceeds the variation threshold. controlling, with one or more computing devices, movement of a boom of the work vehicle such that the boom is moved across a plurality of overlapping measurement regions defined along an angular travel range of the boom, each measurement region being overlapped by at least one adjacent measurement region of the plurality of overlapping measurement regions across the angular travel range; receiving, with the one or more computing devices, load-related data associated with a load weight for the implement as the boom is moved across the plurality of overlapping measurement regions; determining, with the one or more computing devices, a region load weight for at least one measurement region of the plurality of overlapping measurement regions based on the load-related data; and calculating, with the one or more computing devices, a final load weight for the implement based on the region load weight for the at least one measurement region; the method being characterized in that it further comprises: receiving operator-initiated control commands associated with controlling an operation of at least one component of the work vehicle as the boom is moved across the plurality of overlapping measurement regions; identifying a first group of measurement regions of the plurality of overlapping measurement regions across which a variation in the operator-initiated control commands is less than a variation threshold; and identifying at least one second measurement region of the plurality of overlapping measurement regions across which the variation in the operator-initiated control commands exceeds the variation threshold. receiving operator-initiated control commands associated with controlling an operation of at least one component of the work vehicle as the boom is moved across the plurality of overlapping measurement regions; identifying a first group of measurement regions of the plurality of overlapping measurement regions across which a variation in the operator-initiated control commands is less than a variation threshold; and identifying at least one second measurement region of the plurality of overlapping measurement regions across which the variation in the operator-initiated control commands exceeds the variation threshold.