mhurhangee/ep-ind-claims huggingface dataset:
A sample processing system comprising: a first base comprising an upper surface; a sample plate mounted to the upper surface, the sample plate comprising: a top surface, a plurality of wells mounted to the top surface, each well comprising a well bottom surface and a well wall extending up from the well bottom surface, a plurality of reservoirs mounted to the top surface, each reservoir surrounding a corresponding well of the plurality of wells, and comprising a reservoir bottom surface and a reservoir wall defining, together with the well wall of the corresponding well, an interior of the reservoir; and a sliding head mounted to the first base to translate over the sample plate in a translation direction, the sliding head comprising: a housing comprising a second base, a magnet mounted in the housing to extend through the second base, and an adapter mounted to the second base. a first base comprising an upper surface; a sample plate mounted to the upper surface, the sample plate comprising: a top surface, a plurality of wells mounted to the top surface, each well comprising a well bottom surface and a well wall extending up from the well bottom surface, a plurality of reservoirs mounted to the top surface, each reservoir surrounding a corresponding well of the plurality of wells, and comprising a reservoir bottom surface and a reservoir wall defining, together with the well wall of the corresponding well, an interior of the reservoir; and a top surface, a plurality of wells mounted to the top surface, each well comprising a well bottom surface and a well wall extending up from the well bottom surface, a plurality of reservoirs mounted to the top surface, each reservoir surrounding a corresponding well of the plurality of wells, and comprising a reservoir bottom surface and a reservoir wall defining, together with the well wall of the corresponding well, an interior of the reservoir; and a sliding head mounted to the first base to translate over the sample plate in a translation direction, the sliding head comprising: a housing comprising a second base, a magnet mounted in the housing to extend through the second base, and an adapter mounted to the second base. a housing comprising a second base, a magnet mounted in the housing to extend through the second base, and an adapter mounted to the second base.
An inhibitor of bacterial phospholipase A 2, A 1, B, C and/or D for use in a method of treatment of inflammatory bacterial diseases of the intestine in a subject, wherein said inhibitor is a lysophospholipid chemically coupled to a bile acid.
A highly branched polymer characterized by comprising repeating units of formula or formula below wherein Ar 1 to Ar 3 are each independently a divalent organic group of any one of formulas to below in which R 5 to R 38 are each independently a hydrogen atom, a halogen atom, an alkyl group of 1 to 5 carbons which may have a branched structure, an alkoxy group of 1 to 5 carbons which may have a branched structure, or a carboxyl group, sulfo group, phosphoric acid group, phosphonic acid group or salt of any thereof; Z 1 and Z 2 are each independently a hydrogen atom, an alkyl group of 1 to 5 carbons which may have a branched structure, or a monovalent organic group of any one of formulas to below in which R 39 to R 62 are each independently a hydrogen atom, a halogen atom, an alkyl group of 1 to 5 carbons which may have a branched structure, a haloalkyl group of 1 to 5 carbons which may have a branched structure, a phenyl group, OR 63, COR 63, NR 63 R 64, COOR 65, a carboxyl group, sulfo group, phosphoric acid group, phosphonic acid group or salt of any thereof, R 63 and R 64 being each independently a hydrogen atom, an alkyl group of 1 to 5 carbons which may have a branched structure, a haloalkyl group of 1 to 5 carbons which may have a branched structure, or a phenyl group; and R 65 being an alkyl group of 1 to 5 carbons which may have a branched structure, a haloalkyl group of 1 to 5 carbons which may have a branched structure, or a phenyl group, with the proviso that Z 1 and Z 2 are not both alkyl groups; and R 1 to R 4 in formula are each independently a hydrogen atom, a halogen atom, an alkyl group of 1 to 5 carbons which may have a branched structure, an alkoxy group of 1 to 5 carbons which may have a branched structure, or a carboxyl group, sulfo group, phosphoric acid group, phosphonic acid group or salt of any thereof; with the proviso that at least one type of acidic group selected from among sulfo groups, phosphoric acid groups, phosphonic acid groups, and salts thereof is present on at least one aromatic ring of the repeating unit of formula or.
A live attenuated derivative of a pathogenic Enterobacteriaceae species comprising a genetic construction consisting essentially of (a) a means for regulatable expression of a gene that encodes a phoPQ regulatory protein that comprises substituting the promoter of said gene that encodes said phoPQ protein with the araCP BAD repressor-activator-promoter, wherein expression of said phoPQ protein in vivo causes synthesis of antigenic proteins that are conserved among Enterobacteriaceae; and (b) a means for regulatable synthesis of an LPS O-antigen that comprises a mutation in the pmi gene or araCP BAD regulation of any rfb gene cluster gene, wherein said LPS O-antigen ceases to be synthesized in vivo, exposing an LPS core antigen that is conserved among Enterobacteriaceae; wherein said attenuated derivative has enhanced ability to induce cross protective immunity against Enterobacteriaceae. (a) a means for regulatable expression of a gene that encodes a phoPQ regulatory protein that comprises substituting the promoter of said gene that encodes said phoPQ protein with the araCP BAD repressor-activator-promoter, wherein expression of said phoPQ protein in vivo causes synthesis of antigenic proteins that are conserved among Enterobacteriaceae; and (b) a means for regulatable synthesis of an LPS O-antigen that comprises a mutation in the pmi gene or araCP BAD regulation of any rfb gene cluster gene, wherein said LPS O-antigen ceases to be synthesized in vivo, exposing an LPS core antigen that is conserved among Enterobacteriaceae; wherein said attenuated derivative has enhanced ability to induce cross protective immunity against Enterobacteriaceae.
A filter for filtering a fluid having a filter medium located in a housing that comprises an inlet for impure fluid at the housing and an outlet for cleaned fluid at the housing, wherein the filter medium comprises a plurality of filter bodies, - wherein each of the filter bodies has a filter material comprising a fiber fleece that is made of a plurality of synthetic fibers, wherein the adhesive strength of a fiber is increased by a mechanical treatment, whereby the material obtains an increased strength, and - the geometric shape of the filter body corresponds at least approximately to a rotation body; - characterized in that the plurality of filter bodies is located in the filter housing as bulk material. - wherein each of the filter bodies has a filter material comprising a fiber fleece that is made of a plurality of synthetic fibers, wherein the adhesive strength of a fiber is increased by a mechanical treatment, whereby the material obtains an increased strength, and - the geometric shape of the filter body corresponds at least approximately to a rotation body; - characterized in that the plurality of filter bodies is located in the filter housing as bulk material.
Dosing apparatus for dosing of bulk material into block-forming elements and for arrangement on a filling truck of a filling apparatus of a block-forming machine for producing patterned blocks, in particular paving blocks, wherein the filling truck can be pushed forwards and backwards in a displacement direction over block-forming elements and a first bulk material component can be filled into the block-forming elements by the filling truck, and the dosing apparatus comprises at least one filling box, wherein the filling box has a lower outlet which can be opened and closed with the aid of a closure, wherein a second bulk material component can be filled from the filling box into the block-forming elements through the lower outlet, characterised in that the outlet in its open state can still be closed in part-regions in a direction transverse to the displacement direction with the aid of a partial closure element, so that the second bulk material component can be filled into the block forming elements in segments, and the second bulk material component which emerges in segments can be moved to and fro in a transverse direction transverse to the displacement direction and relative to the block-forming elements with the aid of a drive unit which is arranged on the dosing apparatus, wherein the partial closure element has a flat basic shape which is designed to be complementary to the shape of the outlet.
A helmet earpiece, comprising: a body configured to cover at least a portion of an ear; a first feature on the body configured to fit with a complementary first feature associated with a helmet; a second feature on the body configured to fit with a complementary second feature associated with the helmet; wherein the first and second features on the body are configured to fit with the respective complementary first and second features associated with the helmet to detachably mount the helmet earpiece to the helmet without the use of a tool; wherein the first feature on the body comprises: an opening in the body; characterized by the first feature on the body further comprising a lock adjacent the opening, the lock having an unlocked position and a locked position, wherein in the unlocked position, the opening is configured to receive the complementary first feature associated with the helmet, and in the locked position, the lock is configured to retain the complementary first feature in the opening. a body configured to cover at least a portion of an ear; a first feature on the body configured to fit with a complementary first feature associated with a helmet; a second feature on the body configured to fit with a complementary second feature associated with the helmet; wherein the first and second features on the body are configured to fit with the respective complementary first and second features associated with the helmet to detachably mount the helmet earpiece to the helmet without the use of a tool; wherein the first feature on the body comprises: an opening in the body; an opening in the body; characterized by the first feature on the body further comprising a lock adjacent the opening, the lock having an unlocked position and a locked position, wherein in the unlocked position, the opening is configured to receive the complementary first feature associated with the helmet, and in the locked position, the lock is configured to retain the complementary first feature in the opening.
A compound having Formula I, its enantiomers, diastereoisomers, tautomers or a pharmaceutically acceptable salt thereof, wherein: R 1 is N or C-R 10; R 2 is 5-member aromatic heterocycle which may be substituted by hydroxyl, 1 to 2 C 1-3 alkyl or 1 to 2 halogens or cycloalkenyl which may be substituted by 1 to 3 C 1-3 alkyl or 1 or 2 halogens; R 3 is O, N-R 11, or -C; R 4 is H, aromatic heterocycle which may be substituted by hydroxyl, 1 to 2 C 1-3 alkyl or 1 to 2 halogens; non-aromatic heterocycle which may be substituted by hydroxyl, 1 to 2 C 1-3 alkyl or 1 to 2 halogens; cycloalkyl which may be substituted by 1 to 3 C 1-3 alkyl or 1 or 2 halogens; cycloalkenyl which may be substituted by 1 to 3 C 1-3 alkyl or 1 or 2 halogens; or aryl which may be substituted by 1 to 3 halogens or by 1 to 2 C 1-3 alkyl; R 5 is H, halogen, or C 1-3 alkyl; R 6 is H, C 1-3 alkyl, halogen; R 7 is H or C 1-6 alkyl; R 8 is H or C 1-6 alkyl; R 9 is -OPO 3 H 2, -P 2, -S 2 OH, -P MeOH, -P OH or-OR 15; R 10 is H, C 1-6 alkyl, or halogen; R 11 is H or C 1-3 alkyl; R 15 is H or C 1-3 alkyl; L is CHR 16, NR 17 or -C -; a is 0, 1, 2, 3, 4 or 5; b is 0, 1, 2, 3, 4 or 5; c is 0 or 1; d is 1, 2 or 3; R 16 is H, C 1-3 alkyl, -OC 1-3 alkyl, halogen, hydroxyl or amino; and R 17 is H or C 1-3 alkyl; with the proviso: when R 3 is O or N-R 12, and b is 0 or 1 then L is not NR 17; and when R 9 is -OR 15 then d is not 1. R 1 is N or C-R 10; R 2 is 5-member aromatic heterocycle which may be substituted by hydroxyl, 1 to 2 C 1-3 alkyl or 1 to 2 halogens or cycloalkenyl which may be substituted by 1 to 3 C 1-3 alkyl or 1 or 2 halogens; R 3 is O, N-R 11, or -C; R 4 is H, aromatic heterocycle which may be substituted by hydroxyl, 1 to 2 C 1-3 alkyl or 1 to 2 halogens; non-aromatic heterocycle which may be substituted by hydroxyl, 1 to 2 C 1-3 alkyl or 1 to 2 halogens; cycloalkyl which may be substituted by 1 to 3 C 1-3 alkyl or 1 or 2 halogens; cycloalkenyl which may be substituted by 1 to 3 C 1-3 alkyl or 1 or 2 halogens; or aryl which may be substituted by 1 to 3 halogens or by 1 to 2 C 1-3 alkyl; R 5 is H, halogen, or C 1-3 alkyl; R 6 is H, C 1-3 alkyl, halogen; R 7 is H or C 1-6 alkyl; R 8 is H or C 1-6 alkyl; R 9 is -OPO 3 H 2, -P 2, -S 2 OH, -P MeOH, -P OH or-OR 15; R 10 is H, C 1-6 alkyl, or halogen; R 11 is H or C 1-3 alkyl; R 15 is H or C 1-3 alkyl; L is CHR 16, NR 17 or -C -; a is 0, 1, 2, 3, 4 or 5; b is 0, 1, 2, 3, 4 or 5; c is 0 or 1; d is 1, 2 or 3; R 16 is H, C 1-3 alkyl, -OC 1-3 alkyl, halogen, hydroxyl or amino; and R 17 is H or C 1-3 alkyl; with the proviso: when R 3 is O or N-R 12, and b is 0 or 1 then L is not NR 17; and when R 9 is -OR 15 then d is not 1.
An electrolyte configured to provide physical separation between an anode and a cathode of an electrochemical cell, comprising: a room temperature ionic liquid electrolyte comprising an ionic liquid and a dissolved salt, said ionic liquid electrolyte imbibed into a polymer to form a printable non-aqueous gel, and said ionic liquid electrolyte having a concentration of zinc salt between 0.2 and 0.75 M; the electrolyte comprising a composition configured to provide ionic communication between the anode and the cathode by facilitating transmission of multivalent ions across the electrolyte, wherein the dissolved salt releases zinc cations, and wherein the electrolyte forms a flexible layer. a room temperature ionic liquid electrolyte comprising an ionic liquid and a dissolved salt, said ionic liquid electrolyte imbibed into a polymer to form a printable non-aqueous gel, and said ionic liquid electrolyte having a concentration of zinc salt between 0.2 and 0.75 M; the electrolyte comprising a composition configured to provide ionic communication between the anode and the cathode by facilitating transmission of multivalent ions across the electrolyte, wherein the dissolved salt releases zinc cations, and wherein the electrolyte forms a flexible layer.
An apparatus for coating a substrate by reactive sputtering, comprising an axis, at least two targets (11, 12) in an arrangement symmetrically to said axis, a substrate carrier for carrying said substrate and a power supply connected to said targets (11,12), wherein said targets are alternatively operable as cathode and anode, characterised in that the apparatus further comprises means for rotating said substrate carrier around said axis, and further characterised in that said targets (11, 12) are arranged such that a plane defined by an unsputtered front plane of the respective target (11; 12) is angled between 2° and 20° with respect to a plane perpendicular to said axis.
A galactose-fermenting Streptococcus thermophilus strain, wherein the strain carries a mutation in the DNA sequence of the glcK gene encoding a glucokinase protein, wherein the mutation partially or totally inactivates the glucokinase protein, thereby causing the strain to be resistant to 2-deoxyglucose so that it is able to grow to a colony when streaked on a plate of M17 medium containing 2 % (w/v) lactose or 2 % (w/v) galactose, and 20 mM 2-deoxyglucose after incubation at 40 °C for 20 hours.
A dispensing closure for a container containing granular dispensable materials, the dispensing closure comprising: a cap adapted to be received on the container, the cap having an inside face, an outside face, and an aperture extending from the inside face to the outside face through the cap to allow materials within the container to be dispensed; a first movable member positioned adjacent the inside face of the cap to selectively block the aperture in the cap; the first movable member having a passage being movable between a first position in which the aperture is not in communication with the passage and a second position in which the aperture is in communication with the passage, wherein the passage has a first edge and a second edge, the first edge comes into communication with the aperture before the second edge as the first movable member is rotated; and a second movable member positioned adjacent the outside face of the cap to selectively block the aperture in the cap, the second moveable member being movable between a first position in which the aperture is blocked and a second position in which the aperture is not blocked, movement of the first movable member and the second moveable member being sequenced such that at least one of the first movable member and the second moveable member always blocks the aperture, characterized in that the second edge of the passage of the first movable member has a recess positioned along the edge to define a gap between the first movable member and the cap, wherein the gap allows dispensable materials entrapped between the first movable member and the cap to escape. a cap adapted to be received on the container, the cap having an inside face, an outside face, and an aperture extending from the inside face to the outside face through the cap to allow materials within the container to be dispensed; a first movable member positioned adjacent the inside face of the cap to selectively block the aperture in the cap; the first movable member having a passage being movable between a first position in which the aperture is not in communication with the passage and a second position in which the aperture is in communication with the passage, wherein the passage has a first edge and a second edge, the first edge comes into communication with the aperture before the second edge as the first movable member is rotated; and a second movable member positioned adjacent the outside face of the cap to selectively block the aperture in the cap, the second moveable member being movable between a first position in which the aperture is blocked and a second position in which the aperture is not blocked, movement of the first movable member and the second moveable member being sequenced such that at least one of the first movable member and the second moveable member always blocks the aperture, characterized in that the second edge of the passage of the first movable member has a recess positioned along the edge to define a gap between the first movable member and the cap, wherein the gap allows dispensable materials entrapped between the first movable member and the cap to escape.
A touch display panel comprising: a color filter substrate; an array substrate opposite to the color filter substrate; a liquid crystal layer positioned between the color filter substrate and the array substrate; and a touch sensing film positioned at a side of the color filter substrate which is away from the liquid crystal layer; wherein the color filter substrate comprises a first substrate and a black matrix provided on the first substrate, and the black matrix is provided with a plurality of opening areas which are in array distribution; the touch sensing film comprises a second substrate, one side of the second substrate is provided with a plurality of first electrodes in parallel with each other and each having a strip-like structure, the other side of the second substrate is provided with a plurality of second electrodes in parallel with each other and each having a strip-like structure, the projections of the first electrodes and the second electrodes on the color filter substrate are intersected with each other, characterized in that the first electrodes are color filter electrodes with color filtering function, and the projections of the first electrodes on the color filter substrate are opposite to the opening areas which are in array distribution. a color filter substrate; an array substrate opposite to the color filter substrate; a liquid crystal layer positioned between the color filter substrate and the array substrate; and a touch sensing film positioned at a side of the color filter substrate which is away from the liquid crystal layer; wherein the color filter substrate comprises a first substrate and a black matrix provided on the first substrate, and the black matrix is provided with a plurality of opening areas which are in array distribution; the touch sensing film comprises a second substrate, one side of the second substrate is provided with a plurality of first electrodes in parallel with each other and each having a strip-like structure, the other side of the second substrate is provided with a plurality of second electrodes in parallel with each other and each having a strip-like structure, the projections of the first electrodes and the second electrodes on the color filter substrate are intersected with each other, characterized in that the first electrodes are color filter electrodes with color filtering function, and the projections of the first electrodes on the color filter substrate are opposite to the opening areas which are in array distribution.
A cooling device comprising a cabin wherein food and beverages are stored, one or more doors providing access to the inside of the cabin, one or more drawers inside the cabin in which food and beverages are stored, more than one rail situated opposite each other on the side surfaces of the cabin on which the drawer slides, and characterized by at least one roller that facilitates the movement of the drawer situated on it, a shaft that provides the rotation of the roller around itself, a casing that houses the roller situated inside, protecting it from outside effects, a casing housing situated on the cabin and in front of the rail, and provided as a recess in the inner wall of the cabin without harming the inner surface of the cabin, which casing housing is in matching shape to the casing and, inside which the casing is positioned, and a fixing element that provides the mounting of the casing, the shaft and the roller to the casing housing all at once.