A compound represented by structural Formula or pharmaceutically acceptable salts thereof: wherein: Ar is each R is independently selected from H, OH, halogen, nitro, amino, (C 1 -C 6)alkyl, (C=O)(C 0 -C 6)alkyl, (C=O)O(C 0 -C 6)alkyl, NH(C=O)(C 0 -C 6)alkyl, OCF 3, CH=CH(C 0 -C 6)alkyl aryl, O(C 1 -C 6)alkenyl, (C 0 -C 6)alkylCH=O, O(C 1 -C 6)alkyl, S(C 1 -C 6)alkyl, S(C 1 -C 6)haloalkyl, O(C 1 -C 6)haloalkyl, OCHF 2, O(C 0 -C 6)alkylamino, (C 6 -C 10)aryl, (C 5 -C 10)heteroaryl, (C 5 -C 10)heterocyclyl, (C 1 -C 6)alkyl aryl, O(C 0 -C 6)alkyl aryl, O(CH 2) m CHCH 2 or 1-5-membered polycyclyl, wherein each 1-5-membered polycycle optionally and independently contains 1-2 ring heteroatoms selected from oxygen, nitrogen and sulfur; n is 1, 2, 3 or 4; m is 0, 1, 2, 3 or 4; p is 1, 2, 3, 4, or 5; wherein, when n is 2 or greater, the R substituents may be optionally taken together to form a fused polycyclic aromatic ring system; and wherein each R is optionally substituted with 1-4 R 2 substituents independently selected from: (C 1 -C 6)alkyl, halo(C 0 -C 6)alkyl, hydroxy(C 0 -C 6)alkyl, (C 6 -C 10)aryl, halo (C 6 -C 10)aryl, hydroxy(C 6 -C 10)aryl, O(C 1 -C 6)alkyl, O(C 1 -C 6)haloalkyl, (C 3 -C 8)cycloalkyl, halo(C 6 -C 10)aryl(C 1 -C 6)alkoxy, halogen, amino, (C 1 -C 6)alkoxy(C 6 -C 10)aryl(C 1 -C 6)alkoxy, nitro, hydroxy, halogen, (C 0 -C 6)alkyl(C 6 -C 10)aryl(C 0 -C 6)alkoxy, (C 5 -C 10)heterocycle, OCF 3, amino, O(C 1 -C 6)alkylamino, (C 6 -C 10)aryl(C 2 -C 6)alkenyl, (C 2 -C 6)alkenyl(C 1 -C 6)alkoxy, (C 1 -C 6)sulfoxy, (C=O)O(C 0 -C 6)alkyl or N(CH 3)(C 1 -C 6)OH; R 1 is H, C=O(C 0 -C 6)haloalkyl, C=O(C 0 -C 6)alkyl, C=O(C 0 -C 6)alkylene or C=O(C 6 -C 10)aryl. Ar is each R is independently selected from H, OH, halogen, nitro, amino, (C 1 -C 6)alkyl, (C=O)(C 0 -C 6)alkyl, (C=O)O(C 0 -C 6)alkyl, NH(C=O)(C 0 -C 6)alkyl, OCF 3, CH=CH(C 0 -C 6)alkyl aryl, O(C 1 -C 6)alkenyl, (C 0 -C 6)alkylCH=O, O(C 1 -C 6)alkyl, S(C 1 -C 6)alkyl, S(C 1 -C 6)haloalkyl, O(C 1 -C 6)haloalkyl, OCHF 2, O(C 0 -C 6)alkylamino, (C 6 -C 10)aryl, (C 5 -C 10)heteroaryl, (C 5 -C 10)heterocyclyl, (C 1 -C 6)alkyl aryl, O(C 0 -C 6)alkyl aryl, O(CH 2) m CHCH 2 or 1-5-membered polycyclyl, wherein each 1-5-membered polycycle optionally and independently contains 1-2 ring heteroatoms selected from oxygen, nitrogen and sulfur; n is 1, 2, 3 or 4; m is 0, 1, 2, 3 or 4; p is 1, 2, 3, 4, or 5; wherein, when n is 2 or greater, the R substituents may be optionally taken together to form a fused polycyclic aromatic ring system; and wherein each R is optionally substituted with 1-4 R 2 substituents independently selected from: (C 1 -C 6)alkyl, halo(C 0 -C 6)alkyl, hydroxy(C 0 -C 6)alkyl, (C 6 -C 10)aryl, halo (C 6 -C 10)aryl, hydroxy(C 6 -C 10)aryl, O(C 1 -C 6)alkyl, O(C 1 -C 6)haloalkyl, (C 3 -C 8)cycloalkyl, halo(C 6 -C 10)aryl(C 1 -C 6)alkoxy, halogen, amino, (C 1 -C 6)alkoxy(C 6 -C 10)aryl(C 1 -C 6)alkoxy, nitro, hydroxy, halogen, (C 0 -C 6)alkyl(C 6 -C 10)aryl(C 0 -C 6)alkoxy, (C 5 -C 10)heterocycle, OCF 3, amino, O(C 1 -C 6)alkylamino, (C 6 -C 10)aryl(C 2 -C 6)alkenyl, (C 2 -C 6)alkenyl(C 1 -C 6)alkoxy, (C 1 -C 6)sulfoxy, (C=O)O(C 0 -C 6)alkyl or N(CH 3)(C 1 -C 6)OH; R 1 is H, C=O(C 0 -C 6)haloalkyl, C=O(C 0 -C 6)alkyl, C=O(C 0 -C 6)alkylene or C=O(C 6 -C 10)aryl. (C 1 -C 6)alkyl, halo(C 0 -C 6)alkyl, hydroxy(C 0 -C 6)alkyl, (C 6 -C 10)aryl, halo (C 6 -C 10)aryl, hydroxy(C 6 -C 10)aryl, O(C 1 -C 6)alkyl, O(C 1 -C 6)haloalkyl, (C 3 -C 8)cycloalkyl, halo(C 6 -C 10)aryl(C 1 -C 6)alkoxy, halogen, amino, (C 1 -C 6)alkoxy(C 6 -C 10)aryl(C 1 -C 6)alkoxy, nitro, hydroxy, halogen, (C 0 -C 6)alkyl(C 6 -C 10)aryl(C 0 -C 6)alkoxy, (C 5 -C 10)heterocycle, OCF 3, amino, O(C 1 -C 6)alkylamino, (C 6 -C 10)aryl(C 2 -C 6)alkenyl, (C 2 -C 6)alkenyl(C 1 -C 6)alkoxy, (C 1 -C 6)sulfoxy, (C=O)O(C 0 -C 6)alkyl or N(CH 3)(C 1 -C 6)OH; R 1 is H, C=O(C 0 -C 6)haloalkyl, C=O(C 0 -C 6)alkyl, C=O(C 0 -C 6)alkylene or C=O(C 6 -C 10)aryl.