A compound as shown in formulation: wherein the R is selected from the groups consisting of: i) halo, amino, hydroxyl and thiol groups; ii) nitrogen-containing linear alkyl chains of NH(CH 2) n H, alkyl groups with substituted side chains, alkyl side chains with a substituted amino group and alkyl side chains with a substituted hydroxyl group, wherein 1 ≤ n ≤ 10; iii) O(CH 2) n H, N(CH 3) 2, NH(CH 2) n NH(CH 2) n OH, wherein 1 ≤ n ≤ 10; iv) nitrogen-containing cycloalkyl groups and heterocyclic compounds of C 3-12 which contain 1 to 3 heteroatoms selected from the group consisting of O, S and N, wherein the ortho-, para- and meta- position can be further selected independently from one of the groups consisting of: hydrogen group, (CH 2) n H alkyl groups, (CH 2) n hydroxyl groups, (CH 2) n C 3-12 cycloalkyl groups, (CH 2) n C 3-12 nitrogen-containing cycloalkyl groups, (CH 2) n benzene rings, formyl group and (CH 2) n CO C 3-12 nitrogen-containing cycloalkyl groups, wherein 0 ≤ n ≤ 10; v) NH(CH 2) n R 1, 0 ≤ n ≤ 10, wherein R 1 is selected from the groups consisting of: N(CH 3) 2, C(NH 2) 2, linear alkyl chains of NH(CH 2) n H, alkyl groups with substituted side chains, alkyl side chains with a substituted amino group and alkyl side chains with a substituted hydroxyl group; vi) NH(CH 2) n R 2, 0 ≤ n ≤ 10, wherein R 2 is selected from the groups consisting of: benzene rings, C 3-12 cycloalkyl groups and heterocyclic groups of which contain 1 to 3 heteroatoms selected from the group consisting of O, S and N, wherein the ortho-, para- and meta- position can be further selected independently from one of the groups consisting of: Methoxyl group, amino group, benzene rings, alkyl, amino, nitro,hydroxyl groups with substituted C1-C3 side chains and C 3-12 heterocyclic groups; wherein the C 3-12 heterocyclic groups which contain 1 to 3 heteroatoms selected from the group consisting of O, S and N; and their pharmaceutically acceptable salts, stereoisomers and enantiomers. i) halo, amino, hydroxyl and thiol groups; ii) nitrogen-containing linear alkyl chains of NH(CH 2) n H, alkyl groups with substituted side chains, alkyl side chains with a substituted amino group and alkyl side chains with a substituted hydroxyl group, wherein 1 ≤ n ≤ 10; iii) O(CH 2) n H, N(CH 3) 2, NH(CH 2) n NH(CH 2) n OH, wherein 1 ≤ n ≤ 10; iv) nitrogen-containing cycloalkyl groups and heterocyclic compounds of C 3-12 which contain 1 to 3 heteroatoms selected from the group consisting of O, S and N, wherein the ortho-, para- and meta- position can be further selected independently from one of the groups consisting of: hydrogen group, (CH 2) n H alkyl groups, (CH 2) n hydroxyl groups, (CH 2) n C 3-12 cycloalkyl groups, (CH 2) n C 3-12 nitrogen-containing cycloalkyl groups, (CH 2) n benzene rings, formyl group and (CH 2) n CO C 3-12 nitrogen-containing cycloalkyl groups, wherein 0 ≤ n ≤ 10; v) NH(CH 2) n R 1, 0 ≤ n ≤ 10, wherein R 1 is selected from the groups consisting of: N(CH 3) 2, C(NH 2) 2, linear alkyl chains of NH(CH 2) n H, alkyl groups with substituted side chains, alkyl side chains with a substituted amino group and alkyl side chains with a substituted hydroxyl group; vi) NH(CH 2) n R 2, 0 ≤ n ≤ 10, wherein R 2 is selected from the groups consisting of: benzene rings, C 3-12 cycloalkyl groups and heterocyclic groups of which contain 1 to 3 heteroatoms selected from the group consisting of O, S and N, wherein the ortho-, para- and meta- position can be further selected independently from one of the groups consisting of: Methoxyl group, amino group, benzene rings, alkyl, amino, nitro,hydroxyl groups with substituted C1-C3 side chains and C 3-12 heterocyclic groups; wherein the C 3-12 heterocyclic groups which contain 1 to 3 heteroatoms selected from the group consisting of O, S and N;