A method comprising: collecting pressure data while aspirating a gas into a pipette tip attached to a pipette at a given rate of aspiration in a range of 300 μL/sec to 700 μL/sec, the pressure data including a plurality of pressure values measured at an internal portion of the pipette and taken over a given time interval, the plurality of pressure values including a maximum pressure value and a minimum pressure value; estimating a pressure range value between the maximum pressure value and the minimum pressure value, wherein estimating the pressure range value between the maximum pressure value and the minimum pressure value comprises subtracting the minimum pressure value from the maximum pressure value to obtain the pressure range value; responsive to the pressure range value being greater than or equal to a lower threshold and the pressure range value being less than or equal to an upper threshold, determining that the pipette tip attached to the pipette is properly functioning and is suitable to aspirate and dispense a liquid, or responsive to the pressure range value being greater than an upper threshold, determining that the pipette tip attached to the pipette is not properly functioning, wherein said not properly functioning pipette tip comprises said pipette tip being defective, clogged, and/or improperly attached to the pipette, or responsive to the pressure range value being less than the lower threshold, detecting that the pipette tip without a filter or determining that the pipette tip attached to the pipette is not properly functioning wherein said not properly functioning pipette tip comprises said pipette tip being defective, clogged, and/or improperly attached to the pipette; wherein at least one of the upper threshold and the lower threshold is determined using the given rate of aspiration in a range of 300 μL/sec to 700 μL/sec. collecting pressure data while aspirating a gas into a pipette tip attached to a pipette at a given rate of aspiration in a range of 300 μL/sec to 700 μL/sec, the pressure data including a plurality of pressure values measured at an internal portion of the pipette and taken over a given time interval, the plurality of pressure values including a maximum pressure value and a minimum pressure value; estimating a pressure range value between the maximum pressure value and the minimum pressure value, wherein estimating the pressure range value between the maximum pressure value and the minimum pressure value comprises subtracting the minimum pressure value from the maximum pressure value to obtain the pressure range value; responsive to the pressure range value being greater than or equal to a lower threshold and the pressure range value being less than or equal to an upper threshold, determining that the pipette tip attached to the pipette is properly functioning and is suitable to aspirate and dispense a liquid, or responsive to the pressure range value being greater than an upper threshold, determining that the pipette tip attached to the pipette is not properly functioning, wherein said not properly functioning pipette tip comprises said pipette tip being defective, clogged, and/or improperly attached to the pipette, or responsive to the pressure range value being less than the lower threshold, detecting that the pipette tip without a filter or determining that the pipette tip attached to the pipette is not properly functioning wherein said not properly functioning pipette tip comprises said pipette tip being defective, clogged, and/or improperly attached to the pipette; wherein at least one of the upper threshold and the lower threshold is determined using the given rate of aspiration in a range of 300 μL/sec to 700 μL/sec.