An aziridine compound with absolute configuration R represented by Formula I: wherein: R 1 is -CH 2 SR 3, wherein R 3 is C 1 -C 4 alkyl; or R 1 is -CH 2 OR 4, wherein R 4 is selected from the group consisting of methyl, substituted methyl, tetrahydropyranyl, methoxyphenyl, ethyl, benzyl, substituted benzyl and silyl; wherein the substituted methyl is selected from the group consisting of methoxymethyl, methylthiomethyl, benzyloxymethyl, (p-methoxybenzyloxy)methyl, 2-methoxyethoxymethyl, and 2-trimethylsilylethoxymethyl; the substituted benzyl is selected from the group consisting of p-methoxybenzyl, 3,4-dimethoxybenzyl and p-nitrobenzyl; the silyl is selected from the group consisting of trimethylsilyl, triethylsilyl, tri-isopropylsilyl, tert-butyldimethylsilyl, tert-butyldiphenylsilyl, diphenylmethylsilyl and tert-butylmethoxyphenylsilyl; and R 2 is selected from the group consisting of hydrogen, formate group, acyl, sulfonyl, benzyl and 4-methoxybenzyl; wherein the formate group is selected from the group consisting of methoxycarbonyl, ethoxycarbonyl, 9-fluorenylmethoxycarbonyl, 2-chloro-3-indenylmethoxycarbonyl, 2,2,2-trichloroethoxycarbonyl, 2-trimethylsilylethoxycarbonyl, homobenzyloxycarbonyl, tert-butoxycarbonyl, benzyloxycarbonyl and allyloxycarbonyl; the acyl is selected from the group consisting of formyl, acetyl, trifluoroacetyl and benzoyl; the sulfonyl is benzenesulfonyl or trifluoromethylsulfonyl. R 1 is -CH 2 SR 3, wherein R 3 is C 1 -C 4 alkyl; or R 1 is -CH 2 OR 4, wherein R 4 is selected from the group consisting of methyl, substituted methyl, tetrahydropyranyl, methoxyphenyl, ethyl, benzyl, substituted benzyl and silyl; wherein the substituted methyl is selected from the group consisting of methoxymethyl, methylthiomethyl, benzyloxymethyl, (p-methoxybenzyloxy)methyl, 2-methoxyethoxymethyl, and 2-trimethylsilylethoxymethyl; the substituted benzyl is selected from the group consisting of p-methoxybenzyl, 3,4-dimethoxybenzyl and p-nitrobenzyl; the silyl is selected from the group consisting of trimethylsilyl, triethylsilyl, tri-isopropylsilyl, tert-butyldimethylsilyl, tert-butyldiphenylsilyl, diphenylmethylsilyl and tert-butylmethoxyphenylsilyl; and wherein the substituted methyl is selected from the group consisting of methoxymethyl, methylthiomethyl, benzyloxymethyl, (p-methoxybenzyloxy)methyl, 2-methoxyethoxymethyl, and 2-trimethylsilylethoxymethyl; the substituted benzyl is selected from the group consisting of p-methoxybenzyl, 3,4-dimethoxybenzyl and p-nitrobenzyl; the silyl is selected from the group consisting of trimethylsilyl, triethylsilyl, tri-isopropylsilyl, tert-butyldimethylsilyl, tert-butyldiphenylsilyl, diphenylmethylsilyl and tert-butylmethoxyphenylsilyl; and R 2 is selected from the group consisting of hydrogen, formate group, acyl, sulfonyl, benzyl and 4-methoxybenzyl; wherein the formate group is selected from the group consisting of methoxycarbonyl, ethoxycarbonyl, 9-fluorenylmethoxycarbonyl, 2-chloro-3-indenylmethoxycarbonyl, 2,2,2-trichloroethoxycarbonyl, 2-trimethylsilylethoxycarbonyl, homobenzyloxycarbonyl, tert-butoxycarbonyl, benzyloxycarbonyl and allyloxycarbonyl; the acyl is selected from the group consisting of formyl, acetyl, trifluoroacetyl and benzoyl; the sulfonyl is benzenesulfonyl or trifluoromethylsulfonyl. wherein the formate group is selected from the group consisting of methoxycarbonyl, ethoxycarbonyl, 9-fluorenylmethoxycarbonyl, 2-chloro-3-indenylmethoxycarbonyl, 2,2,2-trichloroethoxycarbonyl, 2-trimethylsilylethoxycarbonyl, homobenzyloxycarbonyl, tert-butoxycarbonyl, benzyloxycarbonyl and allyloxycarbonyl; the acyl is selected from the group consisting of formyl, acetyl, trifluoroacetyl and benzoyl; the sulfonyl is benzenesulfonyl or trifluoromethylsulfonyl.