mhurhangee/ep-ind-claims huggingface dataset:
A composition for use as a pharmaceutical, wherein the composition comprises an erythropoietin to which two or more straight-chain polyethylene glycol of 5-40 kDa are added, wherein an amount of said erythropoietin is not less than 50% of total erythropoietin, and wherein the erythropoietin is selected from the following (a) to (c): (a) a polypeptide having an amino acid sequence set forth in SEQ ID NO:1; (b) a polypeptide that has an amino acid sequence of not less than 90% sequence identity to the amino acid sequence set forth in SEQ ID NO:1, and has an erythropoietin activity in a cell proliferation assay using BaF/EPOR cells; or (c) a polypeptide that has not more than 30 amino acid substitutions, deletions, insertions and/or additions with respect to the amino acid sequence set forth in SEQ ID NO:1, and has an erythropoietin activity in a cell proliferation assay using BaF/EPOR cells. (a) a polypeptide having an amino acid sequence set forth in SEQ ID NO:1; (b) a polypeptide that has an amino acid sequence of not less than 90% sequence identity to the amino acid sequence set forth in SEQ ID NO:1, and has an erythropoietin activity in a cell proliferation assay using BaF/EPOR cells; or (c) a polypeptide that has not more than 30 amino acid substitutions, deletions, insertions and/or additions with respect to the amino acid sequence set forth in SEQ ID NO:1, and has an erythropoietin activity in a cell proliferation assay using BaF/EPOR cells.
Heatable roller having a circular-cylindrical tubular jacket made of heat-conductive metal which is closed at its end faces with caps (2, 3), having one or more electrical heating mats which are arranged in the interior of the tubular jacket and cover the entire inner surface of the tubular jacket, having at least one connection journal which is arranged on a cap and through which connection cables for supplying the heating mats with electrical current are guided, and having a slip ring body which is fixed to the connection journal and serves for electrical contacting of the connection cables, characterised in that in the interior of the tubular jacket there is arranged a clamping device (9, 14, 15) which presses the heating mats permanently against the inner surface of the tubular jacket in such a way that the heating mats are in contact with the entire inner surface of the tubular jacket.
Method for producing a three-dimensional object by layer by layer solidifying of a material which is solidifiable under the action of radiation, making use of exposure masks, wherein in order to form each object layer to be solidified of the object in a construction plane, there is generated at least one, preferably a single, digital exposure mask by means of which the radiation is selectively projected into the construction plane, characterized in that for each exposure mask, according to the object layer to be solidified, a single 2-bit bitmap is calculated which assigns either the bit-value "transparent" or the bit-value "non-transparent" to each pixel of the exposure mask, in that the bit-value "transparent" is assigned to at least one surface region of the 2-bit bitmap having a structure size below a limit structure size and in that an exposure texture is assigned to each surface region (66b, 66c) above the limit structure size, said exposure texture being configured in the form of a pattern of pixels with the bit-values "transparent" and "non-transparent".
A fluid monitoring and control system comprising: an information handling system; one or more fluid measurement devices communicatively coupled to the information handling system that are configured to detect the volume or flow rate of one or more fluids introduced into or exiting a well bore; a gas injection apparatus that is configured to introduce one or more noble gases into a fluid or the well bore; a gas extraction system that is configured to extract one or more gaseous samples from one or more fluids exiting the well bore; and a gas analyzer communicatively coupled to the information handling system that is configured to receive one or more gaseous samples from the gas extraction system; wherein the information handling system is configured to receive data from the gas analyzer regarding the presence of the one or more noble gases in the gaseous samples and data from the one or more fluid measurement devices regarding the volume or flow rate of one or more fluids introduced into or exiting the well bore; and wherein the information handling system is configured to use data received from the gas analyzer and the one or more fluid measurement devices to determine one or more parameters selected from the group consisting of: the total volume of the well bore, a lag time in the well bore, a flow characteristic in the well bore, the efficiency of the gas extraction system, and any combination thereof. an information handling system; one or more fluid measurement devices communicatively coupled to the information handling system that are configured to detect the volume or flow rate of one or more fluids introduced into or exiting a well bore; a gas injection apparatus that is configured to introduce one or more noble gases into a fluid or the well bore; a gas extraction system that is configured to extract one or more gaseous samples from one or more fluids exiting the well bore; and a gas analyzer communicatively coupled to the information handling system that is configured to receive one or more gaseous samples from the gas extraction system; wherein the information handling system is configured to receive data from the gas analyzer regarding the presence of the one or more noble gases in the gaseous samples and data from the one or more fluid measurement devices regarding the volume or flow rate of one or more fluids introduced into or exiting the well bore; and wherein the information handling system is configured to use data received from the gas analyzer and the one or more fluid measurement devices to determine one or more parameters selected from the group consisting of: the total volume of the well bore, a lag time in the well bore, a flow characteristic in the well bore, the efficiency of the gas extraction system, and any combination thereof.
A method for managing a power steering comprising a steering mechanism, management method during which the age of said steering mechanism is determined by means of an aging estimation method according to which a value called "aging value" is calculated according to an aging function (old, old2, ene) which corresponds to the integral, over time, of an expression which is weighted by a stress indicator (T m (u), T s (u)) whose value at each considered moment (u) is representative of the intensity of a biasing force (T m, T s) which is experienced by said steering mechanism at said considered moment, said management method being characterized in that it comprises adapting afterwards, as a function of the age determined thereby, at least one assist law and/or one friction model used by an assist law of said power steering and/or at least one elasticity chart which characterizes the stiffness of a movable member of the steering mechanism and/or the stiffness of the kinematic link between two movable members of the steering mechanism.
A vehicle having a lateral lifting device, comprising at least one first axle carrier and one second axle carrier, wherein the two axle carriers (3, 4) are coupled to one another by means of a laterally eccentrically arranged connecting structure and wherein the lifting device is arranged in a free space between the two axle carriers (3, 4), wherein the lifting device comprises at least one first lifting mast with a first vertically displaceable fork holder receptacle and one second lifting mast with a second vertically displaceable fork holder receptacle, wherein the two lifting masts (19, 20) are controlled such that the fork holder receptacles (21, 22) can be displaced synchronously with one another, characterized in that the first lifting mast has a first guide unit on a first side facing the first axle carrier and that the second lifting mast has a second guide unit on a second side facing the second axle carrier, wherein the two guide units (30, 32) each have at least two main guide rollers which are horizontally spaced apart from one another and have a horizontally oriented axis of rotation, said main guide rollers each cooperating with a guide rail which is arranged in the axle carriers (3, 4), wherein the main guide rollers are designed to accommodate the load acting on the lifting device and the torque acting on the lifting device, and that the two guide units (30, 32) each have at least one stabilization module which acts in the horizontal longitudinal direction of the vehicle and which serves to position the main guide rollers horizontally in the guide rail.
Transponder (4.1) comprising at least one wake-up unit (3.0) and at least one data exchange unit (3.1) for bidirectional data communication with at least one reading device (4.5), in particular for acquiring and/or controlling an access authorisation to spaces or objects, wherein the transponder comprises at least one data-emitting transmitter (4.3) and at least one receiver (4.4), wherein the transmitter (4.3) transmits signals automatically at least during some time periods, characterised in that the transponder (4.1) comprises at least one photodiode (1.1) and that the at least one wake-up unit (3.0) is an optical wake-up unit, which is continuously ready to receive signals (4.11) for the start of the data communication by means of the data exchange unit (3.1) between the transponder and the reading device (4.5).
A film forming gel composition for use as a conformable film bandage, the composition comprising: a silicone containing, film forming polymer; a tackifier comprising a silicate tackifying resin; guanidinyl-containing polymer particles having primary or secondary amino groups; and a volatile solvent, wherein a film cast from the composition is self-supporting on a biological substrate and can be peeled off the substrate without substantially compromising the integrity of the film such that at least a portion of the film is removable in a single continuous layer. a silicone containing, film forming polymer; a tackifier comprising a silicate tackifying resin; guanidinyl-containing polymer particles having primary or secondary amino groups; and a volatile solvent, wherein a film cast from the composition is self-supporting on a biological substrate and can be peeled off the substrate without substantially compromising the integrity of the film such that at least a portion of the film is removable in a single continuous layer.
A system for the time-limited storage of objects, comprising a conveyor, which can be moved along an at least partially curved and at least partially inclined path, wherein the path describes a spatial spiral having a plurality of revolutions, and wherein the radius of the spatial spiral becomes smaller in the upward direction in the operating state of the conveyor, such that in each case an upper path segment (8, 9) is closer to the central axis of the spatial spiral than the adjacent lower path segment (7, 8), wherein the conveyor is guided via a plurality of turn rollers, wherein a straight, rising path segment is provided between each two opposite turn rollers, wherein the central axis of the spatial spiral lies in the plane of a first axis of rotation of a first set of concentrically arranged turn rollers (1, 3, 5) rotatable about the first axis of rotation and of a second axis of rotation of a second set of concentrically arranged turn rollers (2, 4) rotatable about the second axis of rotation, in the middle between the first and the second axis of rotation, and wherein the turn rollers (1, 3, 5) rotatable about the first axis of rotation are opposite the turn rollers (2, 4) rotatable about the second axis of rotation, characterised in that in each case an upper path segment (8, 9) is closer to the central axis of the spatial spiral than the adjacent lower path segment (7, 8) by at least the width of the conveyor.
A contact lens applicator container comprising at least one contact lens applicator film for picking up a contact lens and applying the contact lens to an eye, the contact lens applicator film comprising: a sterilised film; wherein at least a portion of at least one side of the film comprises an adhesive coating that is arranged for adhering to the surface of a finger such that, in use, when applying the contact lens to the eye a user can pick up the contact lens applicator film with the finger and subsequently pick up the contact lens using the finger protected by the contact lens applicator film; wherein the contact lens applicator container comprises a recess having a base wall for housing the at least one applicator film; and wherein the base wall is deformable so as to conform to the contour of the finger under the application of finger pressure. wherein the contact lens applicator container comprises a recess having a base wall for housing the at least one applicator film; and wherein the base wall is deformable so as to conform to the contour of the finger under the application of finger pressure.
A processor implemented method for chromosome classification, the method comprising: receiving, via one or more hardware processors, a chromosome image comprising a chromosome with a plurality of chromosome bands; extracting, via one or more hardware processors, visual features associated with the chromosome bands of the chromosome by generating a plurality of feature maps with dimension GxHxK; obtaining, via one or more hardware processors, a plurality of feature vectors from the plurality of feature maps, with each feature vector F g of dimension H*K, by applying horizontal slicing on the plurality of feature maps; concatenating, via one or more hardware processors, the plurality of feature vectors in sequence from a top chromosome band to a bottom chromosome band among the plurality of chromosome bands to generate a feature sequence S i of dimension Gx H*K; and classifying, via one or more hardware processors, the chromosome into a class label among a plurality of pre-determined class labels of chromosomes by processing the feature sequence using a Recurrent Neural Network characterized in that said Recurrent Neural Network is augmented with an attention mechanism, wherein the RNN learns the feature sequence and the attention mechanism concentrates on a plurality of Regions-of-interest (ROIs) of the feature sequence, wherein the ROIs are specific to a class label of chromosomes. receiving, via one or more hardware processors, a chromosome image comprising a chromosome with a plurality of chromosome bands; extracting, via one or more hardware processors, visual features associated with the chromosome bands of the chromosome by generating a plurality of feature maps with dimension GxHxK; obtaining, via one or more hardware processors, a plurality of feature vectors from the plurality of feature maps, with each feature vector F g of dimension H*K, by applying horizontal slicing on the plurality of feature maps; concatenating, via one or more hardware processors, the plurality of feature vectors in sequence from a top chromosome band to a bottom chromosome band among the plurality of chromosome bands to generate a feature sequence S i of dimension Gx H*K; and classifying, via one or more hardware processors, the chromosome into a class label among a plurality of pre-determined class labels of chromosomes by processing the feature sequence using a Recurrent Neural Network characterized in that said Recurrent Neural Network is augmented with an attention mechanism, wherein the RNN learns the feature sequence and the attention mechanism concentrates on a plurality of Regions-of-interest (ROIs) of the feature sequence, wherein the ROIs are specific to a class label of chromosomes.
Measuring device for a boring machine tool that comprises a boring bar, that is movable along and around a working axis and is provided with a first end that is suitable for supporting a machining tool, and a spindle for slidably supporting said boring bar and transmitting a torque thereto at a coupling zone, a first portion of said boring bar comprised between said first end and said coupling zone being subject to torsion, said measuring device comprising: - a tubular element inserted into said boring bar and provided with a first end part fixed to said first end in such a manner that said tubular element rotates together with the latter; - first sensor means associated with said tubular element to detect a first signal indicating rotation of said tubular element and thus of said first end; - second sensor means associated with a second portion of said boring bar that is not subject to torsion to detect a second signal indicating rotation of said boring bar in said second portion; and - a computing unit for receiving and processing said first signal and said second signal and calculating an angular displacement (Δθ) between said first end and said second portion, said angular displacement (Δθ) being a torsion angle to which said first portion is subject. - a tubular element inserted into said boring bar and provided with a first end part fixed to said first end in such a manner that said tubular element rotates together with the latter; - first sensor means associated with said tubular element to detect a first signal indicating rotation of said tubular element and thus of said first end; - second sensor means associated with a second portion of said boring bar that is not subject to torsion to detect a second signal indicating rotation of said boring bar in said second portion; and - a computing unit for receiving and processing said first signal and said second signal and calculating an angular displacement (Δθ) between said first end and said second portion, said angular displacement (Δθ) being a torsion angle to which said first portion is subject.
An optical fiber comprising: a core having an oblong rectangular or square cross section made of quartz; a cladding sorrounding the core, having a circular outer cross-sectional shape; having a lower refractive index than the core, and made of quartz; and a support layer surrounding the cladding and made of quartz; and a protection layer surrounding the support layer and having a higher refractive index than the support layer, wherein the cladding is doped with at least one of fluorine and boron. a core having an oblong rectangular or square cross section made of quartz; a cladding sorrounding the core, having a circular outer cross-sectional shape; having a lower refractive index than the core, and made of quartz; and a support layer surrounding the cladding and made of quartz; and a protection layer surrounding the support layer and having a higher refractive index than the support layer, wherein the cladding is doped with at least one of fluorine and boron.
A vehicle display device (1,201,301) comprising: an emission unit that is mountable on a vehicle and emits display light; an optical system that makes the display light emitted from the emission unit cross along an intersecting direction (Y,Z) intersecting with an optical axis direction of the display light, thereby forming a cross point, and then reflects the display light on a display surface provided to the vehicle toward an eye point that is assumed in advance; a light-blocking wall provided to face an optical path of the display light and including a narrowing part that narrows the optical path toward a cross point of the display light along the intersecting direction (Y,Z), wherein the narrowing part has a narrowing shape so that the distance between a pair of narrowing parts along the vehicle width direction gradually smaller in a manner that the light-blocking wall gets close to the cross point gradually along the vehicle width direction from an end part side to a central part side in the vehicle front-rear direction; and a partial cutoff adjustment structure (6,206,306) that partially cuts off a display image by the display light at a portion other than the narrowing part when the eye point moves along the vehicle width direction. an emission unit that is mountable on a vehicle and emits display light; an optical system that makes the display light emitted from the emission unit cross along an intersecting direction (Y,Z) intersecting with an optical axis direction of the display light, thereby forming a cross point, and then reflects the display light on a display surface provided to the vehicle toward an eye point that is assumed in advance; a light-blocking wall provided to face an optical path of the display light and including a narrowing part that narrows the optical path toward a cross point of the display light along the intersecting direction (Y,Z), wherein the narrowing part has a narrowing shape so that the distance between a pair of narrowing parts along the vehicle width direction gradually smaller in a manner that the light-blocking wall gets close to the cross point gradually along the vehicle width direction from an end part side to a central part side in the vehicle front-rear direction; and a partial cutoff adjustment structure (6,206,306) that partially cuts off a display image by the display light at a portion other than the narrowing part when the eye point moves along the vehicle width direction.
A method of producing a polyimide polymer comprising: (a) reacting at least one acid monomer with at least one diamino monomer to form a polyimide polymer backbone such that the polymer backbone includes at least one non-terminal attachment point, wherein the attachment point is comprised of a carboxylic acid; (b) after step a), reacting a functional group selected from the group consisting of an amine and an alcohol with the polymer backbone attachment point, wherein the functional group is connected to an oligomeric silsesquioxane compound. (a) reacting at least one acid monomer with at least one diamino monomer to form a polyimide polymer backbone such that the polymer backbone includes at least one non-terminal attachment point, wherein the attachment point is comprised of a carboxylic acid; (b) after step a), reacting a functional group selected from the group consisting of an amine and an alcohol with the polymer backbone attachment point, wherein the functional group is connected to an oligomeric silsesquioxane compound.