mhurhangee/ep-ind-claims huggingface dataset:
An agglomerate or capsule prepared by freeze-drying of a first agglomerate or first capsule, said first agglomerate or first capsule comprising a solvent, nanoobjects or nanostructures coated with macromolecules of polysaccharides being distributed homogeneously in said first agglomerate or first capsule, and said macromolecules forming in at least one portion of the first agglomerate or first capsule, a gel by crosslinking with positive ions.
System with a tool adjustment and measuring apparatus for measuring a tool unit, with at least one camera device configured to receive information of the tool unit, with a computing unit configured to generate a dataset of at least a portion of the tool unit at least on the basis of the information, and with a digital further-processing unit configured to supply the dataset in digital form for a machine further-processing, wherein the computing unit is configured to generate a dataset of a rough capturing of at least a portion of the tool unit at least on the basis of the information received by the camera device, wherein the dataset determined by the computing unit from the rough capturing describes a contour outline of the tool unit which is suitable for in-advance calculating of collisions with a workpiece in a machining process, and with an apparatus configured to calculate, via the dataset of the contour outline, whether there is a collision between the tool unit and the workpiece in an envisaged processing of the workpiece.
A low-profile access port for subcutaneous placement in a patient, comprising: a body including: a conduit including an inlet port at a proximal end thereof; and a receiving cup in communication with the inlet port, the receiving cup concavely shaped to direct a catheter-bearing needle into the conduit via the inlet port, the receiving cup to be oriented substantially toward a skin surface when subcutaneously implanted within the patient; and a valve/seal assembly disposed in the conduit that enables passage of the catheter therethrough; characterised by the receiving cup further including a guide groove to direct an impinging distal tip of the catheter-bearing needle toward the inlet port. a body including: a conduit including an inlet port at a proximal end thereof; and a receiving cup in communication with the inlet port, the receiving cup concavely shaped to direct a catheter-bearing needle into the conduit via the inlet port, the receiving cup to be oriented substantially toward a skin surface when subcutaneously implanted within the patient; and a conduit including an inlet port at a proximal end thereof; and a receiving cup in communication with the inlet port, the receiving cup concavely shaped to direct a catheter-bearing needle into the conduit via the inlet port, the receiving cup to be oriented substantially toward a skin surface when subcutaneously implanted within the patient; and a valve/seal assembly disposed in the conduit that enables passage of the catheter therethrough; characterised by the receiving cup further including a guide groove to direct an impinging distal tip of the catheter-bearing needle toward the inlet port.
A subtilase variant having protease activity, wherein the variant is a polypeptide that has at least 80% sequence identity to the polypeptide of SEQ ID NO: 1 and comprises the substitutions N76D, V205I and Q206L, wherein position numbers correspond to the position numbers of the polypeptide of SEQ ID NO: 2.
A cutting tap comprising: an elongate tap body having an axial forward end, an axial rearward end, a central longitudinal axis and a diameter, the elongate tap body having a fluted section at the axial forward end thereof wherein the fluted section presents a flute; the fluted section including a chamfered fluted section beginning at and extending in an axial rearward direction from the axial forward end of the elongate body wherein the chamfered fluted section has an axial rearward termination; and the chamfered fluted section comprising a plurality of cutting threads (58,..., 68) wherein each one of the cutting threads having a cutting face terminating at a distal cutting edge, characterized by the cutting face presenting a convex shape as defined by a transition radius having a center point and the center point of the transition radius moving radial inward relative to the distal cutting edge as the cutting thread moves in the axial rearward direction, and the transition radius ranging from between about five percent to about one hundred percent of the cutting tap diameter.
A homogenization apparatus for pepper raw materials, comprising a base, and an annular storage tank and a stirring barrel coaxially arranged with the base and respectively fixed to the base, characterized in that, the stirring barrel is positioned under the storage tank, the bottom center of the stirring barrel is fixedly connected to a rotating shaft, the stirring barrel is rotationally drivable to rotate together with the rotating shaft about the axis of the rotating shaft, the rotating shaft extends upward into the storage tank, a sleeve is provided on an outer side of the rotating shaft, the rotating shaft is coaxial with the sleeve, so that the stirring barrel rotates relative to the storage tank; a portion of the sleeve accommodated in the stirring barrel is fixedly connected with a stirring part, an upper end of the rotating shaft is fixedly connected with a connecting plate, one end of the connecting plate away from the rotating shaft extends into the storage tank and is connected with a rotatable stirring shaft, and a plurality of stirring blades are fixed to the stirring shaft; an inner wall of the storage tank is provided with a plurality of discharge chutes leading to the stirring tank, and the stirring shaft and the rotating shaft are connected via a transmission assembly.
A device for wound treatment, comprising: a chamber that includes an inner surface and defines a treatment space, the chamber being made of a flexible impermeable material; a plurality of embossed structures configured to engage a wound and to exert mechanical stress on the wound and configured to create pathways through which negative pressure can be distributed and maintained in the treatment space and prevent complete contact between the inner surface and the wound, the plurality of embossed structures intruding from the inner surface of the chamber into the treatment space and being in a concave state relative to the outside of the chamber; and a tube (32, 35) having a first end connected to the chamber, the tube (32, 35) being in fluid communication with the treatment space so as to enable at least one selected from the group of applying negative pressure to the treatment space and applying a therapeutic modality. a chamber that includes an inner surface and defines a treatment space, the chamber being made of a flexible impermeable material; a plurality of embossed structures configured to engage a wound and to exert mechanical stress on the wound and configured to create pathways through which negative pressure can be distributed and maintained in the treatment space and prevent complete contact between the inner surface and the wound, the plurality of embossed structures intruding from the inner surface of the chamber into the treatment space and being in a concave state relative to the outside of the chamber; and a tube (32, 35) having a first end connected to the chamber, the tube (32, 35) being in fluid communication with the treatment space so as to enable at least one selected from the group of applying negative pressure to the treatment space and applying a therapeutic modality.
A medical device comprising: a sensing unit configured to monitor an electrogram signal; a primary sensing channel configured to apply a primary threshold to the EGM signal to detect sense events within the EGM signal, the device being characterised by comprising: a processor configured to detect at least one of bradycardia or asystole based on intervals between sense events detected by the primary sensing channel; a secondary sensing channel configured to apply a secondary threshold, more sensitive than the primary threshold, to the EGM signal to detect under-sensed events within the EGM signal, responsive to the processor detecting at least one of bradychardia or asystole from the primary sensor channel; and wherein the processor is configured to determine whether the detected bradycardia or asystole is false based on detection of under-sensed events by the secondary sensing threshold and intervals between sense events detected by the secondary sensing channel. a sensing unit configured to monitor an electrogram signal; a primary sensing channel configured to apply a primary threshold to the EGM signal to detect sense events within the EGM signal, the device being characterised by comprising: a processor configured to detect at least one of bradycardia or asystole based on intervals between sense events detected by the primary sensing channel; a secondary sensing channel configured to apply a secondary threshold, more sensitive than the primary threshold, to the EGM signal to detect under-sensed events within the EGM signal, responsive to the processor detecting at least one of bradychardia or asystole from the primary sensor channel; and wherein the processor is configured to determine whether the detected bradycardia or asystole is false based on detection of under-sensed events by the secondary sensing threshold and intervals between sense events detected by the secondary sensing channel.
Locking device for a window or door, with a driving rod for moving bolt elements and a main lock case with at least one bolt, which can be moved by means of a key out of a locking position, together with a corresponding driving rod movement, into an opening position, with an arrangement of a second lock cylinder in a second lock case, which actuates the driving rod, wherein the main lock case is configured as a panic lock, and the actuation of the driving rod initiates an unlocking action corresponding to the panic actuation of the first lock case, characterized in that the lock mechanisms of the second lock case are reduced to a pick-off gear wheel and a driving rod thrust element.
A process for the production of styrene monomers by depolymerization of a polystyrene-containing polymer composition, comprising the steps of: a) introducing a polymer composition containing: I) 60% to 99.5% by weight of polystyrene, based on the total weight of the polymer composition; and II) 0.1% to 30% by weight of polyolefin, based on the total weight of the polymer composition; and/or III) 0.1% to 4.9% by weight of acrylonitrile-based polymer, based on the total weight of the polymer composition; and/or IV) 0.1% to 4.9% by weight of polyester, based on the total weight of the polymer composition, into the reaction zone of a pyrolysis reactor; b) thermally cleaving the polystyrene present in the polymer composition in the reaction zone of the pyrolysis reactor at a temperature of from 400°C to 1000°C, in order to obtain a product mixture containing styrene monomers and further components; c) withdrawing the product mixture obtained in step b) from the reaction zone of the pyrolysis reactor; d) cooling the product mixture withdrawn in step c), in order to obtain a condensed product mixture containing styrene monomers and further components; and e) separating the styrene monomers from the further components of the condensed product mixture obtained in step d), wherein the average residence time of the polymer composition in the reaction zone of the pyrolysis reactor is from 0.01 s to 10 s. a) introducing a polymer composition containing: I) 60% to 99.5% by weight of polystyrene, based on the total weight of the polymer composition; and II) 0.1% to 30% by weight of polyolefin, based on the total weight of the polymer composition; and/or III) 0.1% to 4.9% by weight of acrylonitrile-based polymer, based on the total weight of the polymer composition; and/or IV) 0.1% to 4.9% by weight of polyester, based on the total weight of the polymer composition, into the reaction zone of a pyrolysis reactor; I) 60% to 99.5% by weight of polystyrene, based on the total weight of the polymer composition; and II) 0.1% to 30% by weight of polyolefin, based on the total weight of the polymer composition; and/or III) 0.1% to 4.9% by weight of acrylonitrile-based polymer, based on the total weight of the polymer composition; and/or IV) 0.1% to 4.9% by weight of polyester, based on the total weight of the polymer composition, b) thermally cleaving the polystyrene present in the polymer composition in the reaction zone of the pyrolysis reactor at a temperature of from 400°C to 1000°C, in order to obtain a product mixture containing styrene monomers and further components; c) withdrawing the product mixture obtained in step b) from the reaction zone of the pyrolysis reactor; d) cooling the product mixture withdrawn in step c), in order to obtain a condensed product mixture containing styrene monomers and further components; and e) separating the styrene monomers from the further components of the condensed product mixture obtained in step d),
Aqueous dispersion comprising at least one copolymer, the copolymer being preparable by (i) initially charging an aqueous dispersion of at least one polyurethane, and then (ii) polymerizing a mixture of olefinically unsaturated monomers in the presence of the polyurethane from (i), where (a) a water-soluble initiator is used, (b) the metered addition of the olefinically unsaturated monomers is effected such that a concentration of 6.0% by weight, based on the total amount of olefinically unsaturated monomers, in the reaction solution is not exceeded over the entire duration of the reaction, and (c) the mixture of the olefinically unsaturated monomers comprises at least one polyolefinically unsaturated monomer. (i) initially charging an aqueous dispersion of at least one polyurethane, and then (ii) polymerizing a mixture of olefinically unsaturated monomers in the presence of the polyurethane from (i), where (a) a water-soluble initiator is used, (b) the metered addition of the olefinically unsaturated monomers is effected such that a concentration of 6.0% by weight, based on the total amount of olefinically unsaturated monomers, in the reaction solution is not exceeded over the entire duration of the reaction, and (c) the mixture of the olefinically unsaturated monomers comprises at least one polyolefinically unsaturated monomer. (a) a water-soluble initiator is used, (b) the metered addition of the olefinically unsaturated monomers is effected such that a concentration of 6.0% by weight, based on the total amount of olefinically unsaturated monomers, in the reaction solution is not exceeded over the entire duration of the reaction, and (c) the mixture of the olefinically unsaturated monomers comprises at least one polyolefinically unsaturated monomer.
Compressed-air device of a vehicle having an electro-pneumatic brake system which contains an electro-pneumatic parking-brake device with an auxiliary brake function, with at least the following features: a) compressed-air-actuated spring brake cylinders on at least one axle, b) an electronic parking-brake control unit, c) a parking-brake operating device for operating the parking-brake, which in when the auxiliary brake function is activated, emits auxiliary brake demand signals to the electronic parking-brake control unit in a manner that depends on the degree of actuation of a parking-brake operating element of the parking-brake operating device, d) a solenoid valve device controlled by the electronic parking-brake control unit, which as a function of the auxiliary brake demand signals from the parking-brake operating device controls auxiliary brake pressures in the compressed-air-actuated spring brake cylinders on the axle, characterized in that e) means for determining an axle load on the axle are provided, which means emit axle load signals that depend on the axle load on the axle at the time, to the electronic parking-brake control unit, wherein f) the electronic control unit is designed such that on receiving auxiliary brake demand signals from the parking-brake operating device it controls or regulates the auxiliary brake pressure for the compressed-air-actuated spring brake cylinders on the axle as a function of the axle load existing on the axle concerned. a) compressed-air-actuated spring brake cylinders on at least one axle, b) an electronic parking-brake control unit, c) a parking-brake operating device for operating the parking-brake, which in when the auxiliary brake function is activated, emits auxiliary brake demand signals to the electronic parking-brake control unit in a manner that depends on the degree of actuation of a parking-brake operating element of the parking-brake operating device, d) a solenoid valve device controlled by the electronic parking-brake control unit, which as a function of the auxiliary brake demand signals from the parking-brake operating device controls auxiliary brake pressures in the compressed-air-actuated spring brake cylinders on the axle, characterized in that e) means for determining an axle load on the axle are provided, which means emit axle load signals that depend on the axle load on the axle at the time, to the electronic parking-brake control unit, wherein f) the electronic control unit is designed such that on receiving auxiliary brake demand signals from the parking-brake operating device it controls or regulates the auxiliary brake pressure for the compressed-air-actuated spring brake cylinders on the axle as a function of the axle load existing on the axle concerned.
A compression garment, comprising: a fabric sleeve (105, 170); a flex frame proximate a surface of the fabric sleeve (105, 170), the flex frame defining a broad surface and comprising: a series of support regions each having a first height; a series of enclosed openings, each of the series of enclosed openings having a second height and passing orthogonally through the broad surface of the flex frame; a series of bridges, each of the series of bridges having a bridge height smaller than the first height and the second height and coupling adjacent enclosed opening (114, 116) pairs of the series of enclosed openings, the compression garment further comprising: a body of shape memory material, the shape memory material comprising at least one of a shape memory alloy and a shape memory polymer, at least part of the shape memory material retained by the series of support regions in a crossed arrangement along a length of the flex frame; and a controller comprising a microprocessor, the controller electrically connected to the shape memory alloy wire and comprising an active mode wherein, in the active mode: the controller applies a threshold current definition to the shape memory alloy wire and, in response, the shape memory alloy wire transitions from a first length to a second length, the second length smaller than the first length, characterised in that the series of support regions comprises a set of magnetic elements coupled to edges of the series of support regions, the set of magnetic elements providing a magnetic field for retention of the body of shape memory alloy.
A polypeptide comprising a fibronectin based scaffold moiety that comprises a modified 10 th fibronectin type III ( 10 Fn3) domain, wherein the modified 10 Fn3 domain comprises an amino acid sequence wherein the amino acid residue corresponding to the threonine residue at position 58 of SEQ ID NO: 1 is a glutamic acid residue; the solubility of the modified 10 Fn3 domain is enhanced relative to the solubility of a 10 Fn3 domain comprising the same amino acid sequence as the modified 10 Fn3 domain, except that the amino acid residue corresponding to the threonine residue at position 58 of SEQ ID NO: 1 is not mutated; and the modified 10 Fn3 domain binds specifically to a target that is not bound by a human Fn3 domain selected from those set forth in SEQ ID NOs: 1-16, 65 and 66.
A circuit for managing power and heat of a Central Processing Unit, comprising: a motherboard voltage regulator to supply a current to a loadline; a sense point coupled to the loadline, the circuit to measure a sensed voltage at the sense point; a comparator to compare the sensed voltage to a reference voltage, an output of the comparator to indicate a level of current being provided by the motherboard voltage regulator; a second line coupled to the motherboard voltage regulator; a precision resistor at the sense point; an amplifier to cancel out temperature-related variation in the resistance of the loadline by controlling a transistor coupled to an output of the amplifier to increase or decrease a current in the second line, wherein the loadline and the second line are each coupled to an input of the amplifier, and the precision resistor is coupled to the transistor; and a switch to change between voltage mode sensing and current mode sensing. a motherboard voltage regulator to supply a current to a loadline; a sense point coupled to the loadline, the circuit to measure a sensed voltage at the sense point; a comparator to compare the sensed voltage to a reference voltage, an output of the comparator to indicate a level of current being provided by the motherboard voltage regulator; a second line coupled to the motherboard voltage regulator; a precision resistor at the sense point; an amplifier to cancel out temperature-related variation in the resistance of the loadline by controlling a transistor coupled to an output of the amplifier to increase or decrease a current in the second line, wherein the loadline and the second line are each coupled to an input of the amplifier, and the precision resistor is coupled to the transistor; and a switch to change between voltage mode sensing and current mode sensing.
An antibody or antibody derivative that binds to a cancer cell-associated Glypican 2 for use in a method of treating glypican 2 -positive cancer, wherein the method comprises the step of contacting a Glypican 2-positive cancer cell in a subject with said antibody or antibody derivative, wherein the antibody or antibody derivative comprises: (a) a heavy chain variable domain and a light chain variable domain encoded by nucleic acid sequences of SEQ ID NOs. 1 and 3; or (b) a heavy chain variable domain and a light chain variable domain having amino acid sequences of SEQ ID NOs. 2 and 4. (a) a heavy chain variable domain and a light chain variable domain encoded by nucleic acid sequences of SEQ ID NOs. 1 and 3; or (b) a heavy chain variable domain and a light chain variable domain having amino acid sequences of SEQ ID NOs. 2 and 4.