An anti-TF antibody drug conjugate (anti-TF-ADC) comprising an anti-TF antibody selected from the group consisting of: (i) an anti-TF antibody having a VH region comprising a CDR1 region having the amino acid sequence set forth in SEQ ID NO:2, a CDR2 region having the amino acid sequence set forth in SEQ ID NO: 3, and a CDR3 region having the amino acid sequence set forth in SEQ ID NO: 4, and a VL region comprising a CDR1 region having the amino acid sequence set forth in SEQ ID NO:18, a CDR2 region having the amino acid sequence set forth in SEQ ID NO: 19, and a CDR3 region having the amino acid sequence set forth in SEQ ID NO: 20, (ii) an anti-TF antibody having a VH region comprising a CDR1 region having the amino acid sequence set forth in SEQ ID NO:6, a CDR2 region having the amino acid sequence set forth in SEQ ID NO: 7, and a CDR3 region having the amino acid sequence set forth in SEQ ID NO: 8, and a VL region comprising a CDR1 region having the amino acid sequence set forth in SEQ ID NO:22, a CDR2 region having the amino acid sequence set forth in SEQ ID NO: 23, and a CDR3 region having the amino acid sequence set forth in SEQ ID NO: 24, or (iii) an anti-TF antibody having a VH region comprising a CDR1 region having the amino acid sequence set forth in SEQ ID NO:10, a CDR2 region having the amino acid sequence set forth in SEQ ID NO: 11, and a CDR3 region having the amino acid sequence set forth in SEQ ID NO: 12, and a VL region comprising a CDR1 region having the amino acid sequence set forth in SEQ ID NO:26, a CDR2 region having the amino acid sequence set forth in SEQ ID NO: 27, and a CDR3 region having the amino acid sequence set forth in SEQ ID NO: 28, or (iv) an anti-TF antibody having a VH region comprising a CDR1 region having the amino acid sequence set forth in SEQ ID NO:14, a CDR2 region having the amino acid sequence set forth in SEQ ID NO: 15, and a CDR3 region having the amino acid sequence set forth in SEQ ID NO: 16, and a VL region comprising a CDR1 region having the amino acid sequence set forth in SEQ ID NO: 30, a CDR2 region having the amino acid sequence set forth in SEQ ID NO: 31, and a CDR3 region having the amino acid sequence set forth in SEQ ID NO: 32, or (v) a variant of any of said antibodies defined in (i) to (iv), wherein said variant has at most 1, 2 or 3 conservative amino-acid substitutions in the six CDR sequences, wherein the antibody has been conjugated to an auristatin via a linker, said anti-TF-ADC for use in a method of treating a solid cancer wherein the anti-TF-ADC is administered to a subject in need thereof in cycles comprising administration once a week for three consecutive weeks followed by a one week resting period without any administration of anti-TF ADC so that each cycle time is 28 days including the resting period wherein the dose of the anti-TF-ADC is between 0.8 mg/kg and 2.4 mg/kg of the subject's body weight. (i) an anti-TF antibody having a VH region comprising a CDR1 region having the amino acid sequence set forth in SEQ ID NO:2, a CDR2 region having the amino acid sequence set forth in SEQ ID NO: 3, and a CDR3 region having the amino acid sequence set forth in SEQ ID NO: 4, and a VL region comprising a CDR1 region having the amino acid sequence set forth in SEQ ID NO:18, a CDR2 region having the amino acid sequence set forth in SEQ ID NO: 19, and a CDR3 region having the amino acid sequence set forth in SEQ ID NO: 20, (ii) an anti-TF antibody having a VH region comprising a CDR1 region having the amino acid sequence set forth in SEQ ID NO:6, a CDR2 region having the amino acid sequence set forth in SEQ ID NO: 7, and a CDR3 region having the amino acid sequence set forth in SEQ ID NO: 8, and a VL region comprising a CDR1 region having the amino acid sequence set forth in SEQ ID NO:22, a CDR2 region having the amino acid sequence set forth in SEQ ID NO: 23, and a CDR3 region having the amino acid sequence set forth in SEQ ID NO: 24, or (iii) an anti-TF antibody having a VH region comprising a CDR1 region having the amino acid sequence set forth in SEQ ID NO:10, a CDR2 region having the amino acid sequence set forth in SEQ ID NO: 11, and a CDR3 region having the amino acid sequence set forth in SEQ ID NO: 12, and a VL region comprising a CDR1 region having the amino acid sequence set forth in SEQ ID NO:26, a CDR2 region having the amino acid sequence set forth in SEQ ID NO: 27, and a CDR3 region having the amino acid sequence set forth in SEQ ID NO: 28, or (iv) an anti-TF antibody having a VH region comprising a CDR1 region having the amino acid sequence set forth in SEQ ID NO:14, a CDR2 region having the amino acid sequence set forth in SEQ ID NO: 15, and a CDR3 region having the amino acid sequence set forth in SEQ ID NO: 16, and a VL region comprising a CDR1 region having the amino acid sequence set forth in SEQ ID NO: 30, a CDR2 region having the amino acid sequence set forth in SEQ ID NO: 31, and a CDR3 region having the amino acid sequence set forth in SEQ ID NO: 32, or (v) a variant of any of said antibodies defined in (i) to (iv), wherein said variant has at most 1, 2 or 3 conservative amino-acid substitutions in the six CDR sequences,