mhurhangee/ep-ind-claims huggingface dataset:
Minnelide and paclitaxel for use in a method for treating gastric cancer in a cancer patient, the method comprising administering to a gastric cancer patient during a 28 day cycle a therapeutically effective combination of: a)0.25 mg to 2.0 mg ± 25% of minnelide according to a first regimen wherein a dose is given once per day on days 1 to 5, 8 to 12, and 15 to 19 of the cycle; and b)60 mg/m 2 to 100 mg/m 2 ± 25% of paclitaxel according to a second regimen wherein a dose is given once per day on days 1, 8, and 15 of the cycle; wherein the 28-day cycle is repeated one or more times and the combination effectively treats the gastric cancer. a)0.25 mg to 2.0 mg ± 25% of minnelide according to a first regimen wherein a dose is given once per day on days 1 to 5, 8 to 12, and 15 to 19 of the cycle; and b)60 mg/m 2 to 100 mg/m 2 ± 25% of paclitaxel according to a second regimen wherein a dose is given once per day on days 1, 8, and 15 of the cycle;
A method for manufacturing a wind turbine blade shell part made of a composite structure comprising a fibre-reinforcement material embedded in a polymer matrix via vacuum assisted resin transfer moulding, the method comprising the steps of: - mounting a plurality of fastening devices on a first side of a mounting plate so as to form a root end assembly, the mounting plate comprising one or more first openings for evacuating air, the mounting plate having a second side opposite the first side, - arranging the root end assembly, one or more outer fibre layers defining an outer surface of the wind turbine blade shell part, and one or more inner fibre layers on a mould surface of a mould such that the fastening devices are arranged above a root end section of the mould and are embedded between the one or more outer fibre layers and the one or more inner fibre layers, - arranging an air-tight cover member so as to form a mould cavity defined by the air-tight cover member, the mould surface, and the mounting plate, with the one or more outer fibre layers, the one or more inner fibre layers, and the fastening devices arranged within the mould cavity, - evacuating air from the mould cavity via at least the one or more first openings of the mounting plate, and - supplying a polymer into the mould cavity and allowing the polymer to cure so as to form the composite structure. - mounting a plurality of fastening devices on a first side of a mounting plate so as to form a root end assembly, the mounting plate comprising one or more first openings for evacuating air, the mounting plate having a second side opposite the first side, - arranging the root end assembly, one or more outer fibre layers defining an outer surface of the wind turbine blade shell part, and one or more inner fibre layers on a mould surface of a mould such that the fastening devices are arranged above a root end section of the mould and are embedded between the one or more outer fibre layers and the one or more inner fibre layers, - arranging an air-tight cover member so as to form a mould cavity defined by the air-tight cover member, the mould surface, and the mounting plate, with the one or more outer fibre layers, the one or more inner fibre layers, and the fastening devices arranged within the mould cavity, - evacuating air from the mould cavity via at least the one or more first openings of the mounting plate, and - supplying a polymer into the mould cavity and allowing the polymer to cure so as to form the composite structure.
A viscous clutch comprising: an input member; an output member; a working chamber defined between the input member and the output member; a reservoir to hold a supply of a shear fluid, the reservoir fluidically connected to the working chamber by a fluid circuit; a valve, wherein the valve is electromagnetically actuatable to selectively control a flow of the shear fluid between the reservoir and the working chamber along the fluid circuit such that a torque coupling between the input member and the output member can be created as a function of a volume of the shear fluid present in the working chamber; and a control coil assembly that includes: an electromagnetic coil; and a coil bearing; characterized by a securing mechanism removably attached to the input member radially inward of the working chamber and the reservoir, wherein the securing mechanism includes a radially outwardly extending flange, and wherein the control coil assembly further includes a modular center hub removably attached to the input member; and wherein the coil bearing rotatably supports the electromagnetic coil on the modular center hub an input member; an output member; a working chamber defined between the input member and the output member; a reservoir to hold a supply of a shear fluid, the reservoir fluidically connected to the working chamber by a fluid circuit; a valve, wherein the valve is electromagnetically actuatable to selectively control a flow of the shear fluid between the reservoir and the working chamber along the fluid circuit such that a torque coupling between the input member and the output member can be created as a function of a volume of the shear fluid present in the working chamber; and a control coil assembly that includes: an electromagnetic coil; and a coil bearing; an electromagnetic coil; and a coil bearing; characterized by a securing mechanism removably attached to the input member radially inward of the working chamber and the reservoir, wherein the securing mechanism includes a radially outwardly extending flange, and wherein the control coil assembly further includes a modular center hub removably attached to the input member; and wherein the coil bearing rotatably supports the electromagnetic coil on the modular center hub
A method for controlling a drilling robot, of the type including a servo-driven mechanical structure allowing placing a drilling tool in a drilling sequence programming the position and orientation of the drilling of a part such as a technical surface patch, the method including the following steps: a step of determining the acceleration (Ax, Ay, Az) of the drilling tool at the end of the approach on a drilling position, and then testing a stabilization condition of the drilling tool, and finally establishing a drilling enable-command ((c), Figure 2; (d) Figure 3; (a) Figure 7); the step of determining the acceleration (Ax, Ay, Az) of the drilling tool at the end of the approach on a drilling position being carried on after the drilling enable-command ((a), Figure 7) so as to carry out an analysis of the measurement data of the accelerometer, and then exploit the analysis data in real-time in order to trigger a corrective action, such as a cycle-stop command, on the drilling robot and/or on the drilling tool. a step of determining the acceleration (Ax, Ay, Az) of the drilling tool at the end of the approach on a drilling position, and then testing a stabilization condition of the drilling tool, and finally establishing a drilling enable-command ((c), Figure 2; (d) Figure 3; (a) Figure 7); the step of determining the acceleration (Ax, Ay, Az) of the drilling tool at the end of the approach on a drilling position being carried on after the drilling enable-command ((a), Figure 7) so as to carry out an analysis of the measurement data of the accelerometer, and then exploit the analysis data in real-time in order to trigger a corrective action, such as a cycle-stop command, on the drilling robot and/or on the drilling tool.
A non-aqueous electrolyte solution for a lithium secondary battery, the non-aqueous electrolyte solution comprising: a lithium salt; an organic solvent; a compound represented by Formula 1 as a first additive; lithium difluorophosphate (LiDFP) as a second additive; and tetravinylsilane as a third additive, wherein the first additive and the second additive are each independently included in an amount of 0.01 wt% to 8.5 wt% based on a total amount of the non-aqueous electrolyte solution: wherein, in Formula 1, R 1 to R 3 are each independently hydrogen or a substituted or unsubstituted alkyl group having 1 to 6 carbon atoms, and A is wherein R 6 is a substituted or unsubstituted alkyl group having 1 to 6 carbon atoms, a substituted or unsubstituted aryl group having 6 to 12 carbon atoms, or -OR 5; and wherein R 5 is a substituted or unsubstituted alkyl group having 1 to 6 carbon atoms, a substituted or unsubstituted alkynyl group having 2 to 6 carbon atoms, or a substituted or unsubstituted aryl group having 6 to 12 carbon atoms, wherein the substituted alkyl group having 1 to 6 carbon atoms is an alkyl group having 1 to 6 carbon atoms which is substituted with at least one halogen element or an alkyl group having 1 to 6 carbon atoms which is substituted with an alkyl group having 1 to 3 carbon atoms; and wherein the substituted aryl group having 6 to 12 carbon atoms is a phenyl group substituted with at least one halogen element or a phenyl group substituted with an alkyl group having 1 to 3 carbon atoms, and wherein the unsubstituted aryl group having 6 to 12 carbon atoms is a phenyl group. a lithium salt; an organic solvent; a compound represented by Formula 1 as a first additive; lithium difluorophosphate (LiDFP) as a second additive; and tetravinylsilane as a third additive, wherein the first additive and the second additive are each independently included in an amount of 0.01 wt% to 8.5 wt% based on a total amount of the non-aqueous electrolyte solution: wherein, in Formula 1, R 1 to R 3 are each independently hydrogen or a substituted or unsubstituted alkyl group having 1 to 6 carbon atoms, and A is wherein R 6 is a substituted or unsubstituted alkyl group having 1 to 6 carbon atoms, a substituted or unsubstituted aryl group having 6 to 12 carbon atoms, or -OR 5; and wherein R 5 is a substituted or unsubstituted alkyl group having 1 to 6 carbon atoms, a substituted or unsubstituted alkynyl group having 2 to 6 carbon atoms, or a substituted or unsubstituted aryl group having 6 to 12 carbon atoms, wherein the substituted alkyl group having 1 to 6 carbon atoms is an alkyl group having 1 to 6 carbon atoms which is substituted with at least one halogen element or an alkyl group having 1 to 6 carbon atoms which is substituted with an alkyl group having 1 to 3 carbon atoms; and wherein the substituted aryl group having 6 to 12 carbon atoms is a phenyl group substituted with at least one halogen element or a phenyl group substituted with an alkyl group having 1 to 3 carbon atoms, and wherein the unsubstituted aryl group having 6 to 12 carbon atoms is a phenyl group.
A cluster-tool assembly (330; 530) for abrasive flow machining of a plurality of airfoils (302; 502), comprising: an airfoil cluster (200, 252; 300; 406), the airfoil cluster (200, 252; 300; 406) including a supporting rail and the plurality of airfoils (302; 502) spaced about the supporting rail; and characterised by a sacrificial tool unitarily formed with the airfoil cluster (200, 252; 300; 406), the sacrificial tool including a body and a plurality of prongs extending from the body; wherein the sacrificial tool of the cluster-tool assembly (330; 530) is made of a softer material than the material used to fabricate the airfoil cluster (200, 252; 300; 406). an airfoil cluster (200, 252; 300; 406), the airfoil cluster (200, 252; 300; 406) including a supporting rail and the plurality of airfoils (302; 502) spaced about the supporting rail; and characterised by a sacrificial tool unitarily formed with the airfoil cluster (200, 252; 300; 406), the sacrificial tool including a body and a plurality of prongs extending from the body; wherein the sacrificial tool of the cluster-tool assembly (330; 530) is made of a softer material than the material used to fabricate the airfoil cluster (200, 252; 300; 406).
An oral care composition, comprising: a soluble zinc polyphosphate complex in a solvent, said complex made by using zinc chloride and sodium hexametaphosphate; wherein the relative amounts of inorganic zinc salt and long chain polyphosphates provide a phosphorus to zinc mole ratio of 15:1 to 25:1. a soluble zinc polyphosphate complex in a solvent, said complex made by using zinc chloride and sodium hexametaphosphate; wherein the relative amounts of inorganic zinc salt and long chain polyphosphates provide a phosphorus to zinc mole ratio of 15:1 to 25:1.
A device, in particular a composite beam, comprising a hollow profile-shaped outer body having an interior space and a core arranged in the interior space, wherein the core comprises or is formed from a fibre composite material, namely wood, that is swellable upon contact with a fluid, wherein the core in the interior space is swollen by a fluid and exerts a pressure on the outer body generated by the swelling, such that the core is braced in the interior space, characterized in that the core is fluid-tightly enclosed by the outer body and by at least one closure arranged on the outer body.
Household appliance, which has at least one household appliance device with at least one housing unit, with at least one electronics unit, which is arranged at least largely in the housing unit and which has at least one printed circuit board, which is provided to support at least some of the electrical components of the electronics unit, to connect and/or form the same in an electrically conducting manner with one another, and with at least one barrier unit (50, 150), which is provided, at least in an assembled state, to delimit at least one electronics module (60, 160) of the electronics unit from at least a majority of other electronic components of the electronics unit, wherein the barrier unit (50, 150) and the housing unit are embodied separately from one another and the barrier unit (50, 150) is formed at least substantially from plastic, characterised in that the printed circuit board is part of the barrier unit (50, 150) and the barrier unit (50, 150), at least in the assembled state, as a partially open enclosure, wherein viewed from at least each component of the electronics module (60, 160), at most 95% of the full spatial angle is delimited by at least one attachment surface of the barrier unit (50, 150), or at least in the assembled state as an at least essentially closed enclosure, wherein viewed at least from each component of the electronics module (60, 160), at least 95% of the full spatial angle is delimited by at least the attachment surface of the barrier unit (50, 150), wherein at least the one electronics module (60, 160) is embodied as a protective module, wherein the protective module is an electronics module (60, 160), which is provided to protect at least one electric circuit from an overvoltage and/or an overcurrent.
Operating circuit for an LED lamp, comprising: - an input stage for generating a DC voltage (Vdc) from a mains voltage (Vn) supplied to the operating circuit; - a step-down converter for converting the DC voltage (Vdc) into an operating signal for the LED lamp; and - a controller which is designed to: - monitor a difference between the voltage level of the DC voltage (Vdc) and the voltage level of the operating signal, and control a speed of an adjustment process of the operating signal depending on the monitored difference, wherein the adjustment process is a dimming process and the controller is designed to reduce the speed of the dimming process if the difference falls below a first threshold value, wherein during the adjustment process, control signals are generated which are supplied to the step-down converter and the control signals cause the step-down converter to adjust the operating signal accordingly. - an input stage for generating a DC voltage (Vdc) from a mains voltage (Vn) supplied to the operating circuit; - a step-down converter for converting the DC voltage (Vdc) into an operating signal for the LED lamp; and - a controller which is designed to: - monitor a difference between the voltage level of the DC voltage (Vdc) and the voltage level of the operating signal, and control a speed of an adjustment process of the operating signal depending on the monitored difference, wherein the adjustment process is a dimming process and the controller is designed to reduce the speed of the dimming process if the difference falls below a first threshold value,
A soft magnetic material comprising: a compound metal magnetic powder, said metal magnetic powder being formed of multiple particles and a phosphate insulative film surrounding the surface of each particle, wherein said metal magnetic powder is iron powder; characterised in that each particle forming the powder is a collection of multiple crystal grains having an average size of between 10 and 20 microns, and in that each particle includes multiple single crystals having an average size, as determined by X-ray diffraction, of between 30 and 110 nm. a compound metal magnetic powder, said metal magnetic powder being formed of multiple particles and a phosphate insulative film surrounding the surface of each particle, wherein said metal magnetic powder is iron powder; characterised in that each particle forming the powder is a collection of multiple crystal grains having an average size of between 10 and 20 microns, and in that each particle includes multiple single crystals having an average size, as determined by X-ray diffraction, of between 30 and 110 nm.
A vehicle body lower structure (S1, S2) comprising: a side sill; a center tunnel; a floor panel disposed between the side sill and the center tunnel; and first and second frame members (7, 8) connected to a front side member, wherein the first frame member extends obliquely such that the first frame member is located more outward in a vehicle width direction as extending toward a vehicle body rear side, and is connected to the side sill, and the second frame member extends obliquely such that the second frame member is located more inward in the vehicle width direction as extending toward the vehicle body rear side, and is connected to the center tunnel, characterized in that one of the first and second frame members (7, 8) is provided on an upper surface of the floor panel and the other one of the first and second frame members (7, 8) is provided on a lower surface of the floor panel. a side sill; a center tunnel; a floor panel disposed between the side sill and the center tunnel; and first and second frame members (7, 8) connected to a front side member, wherein the first frame member extends obliquely such that the first frame member is located more outward in a vehicle width direction as extending toward a vehicle body rear side, and is connected to the side sill, and the second frame member extends obliquely such that the second frame member is located more inward in the vehicle width direction as extending toward the vehicle body rear side, and is connected to the center tunnel, characterized in that one of the first and second frame members (7, 8) is provided on an upper surface of the floor panel and the other one of the first and second frame members (7, 8) is provided on a lower surface of the floor panel.
A curable silicone composition comprising: (a) a photo-curable silicone resin comprising a free radical curing group selected from acryloxy, methacryloxy, vinyl and combinations thereof; (b) a solid photoinitiator selected from the group consisting of bisacylphosphine oxide, acylphosphine oxide and combinations thereof; (c) a solvent for the solid photoinitiator; and (d) a fluorescent dye. (a) a photo-curable silicone resin comprising a free radical curing group selected from acryloxy, methacryloxy, vinyl and combinations thereof; (b) a solid photoinitiator selected from the group consisting of bisacylphosphine oxide, acylphosphine oxide and combinations thereof; (c) a solvent for the solid photoinitiator; and (d) a fluorescent dye.
Tool holder for the turning of material by means of several tools (17a-17d) tools (17a-17d) arranged to rotate around the material, said tool holder incorporating a plurality of motors (16a-16d), each motor in said plurality of motors comprising a rotor, each said motor (16a-16d) being provided with a longitudinal opening for the passage of material through the motors (16a-16d), characterized in that said motors (16a-16d) are arranged to control independently the respective plunge depths of the tools (17a-17d).
A connector set comprising: a first connector and a first external substrate; a first cap to be attached to the first connector to hold the first connector when it is reflow-mounted on the first external substrate; and a second connector and a second external substrate; and a second cap to be attached to the second connector to hold the second connector when it is reflow-mounted on the second external substrate formed of a material with a smaller thermal expansion coefficient than that of the external first substrate, wherein the first connector comprises: a first housing with a slot; and a plurality of contacts arranged in the slot, the first connector arranged in a direction orthogonal to an extending direction of the slot the second connector comprises a second housing with a header to be fitted in the slot, and a plurality of contacts arranged in a direction orthogonal to an extending direction of the header, wherein when the header is fitted into slots, the contacts of the first connector are electronically connected to the contacts of the second connector, characterised in that, the second cap is formed of a material with a smaller thermal expansion coefficient than that of the first cap. a first connector and a first external substrate; a first cap to be attached to the first connector to hold the first connector when it is reflow-mounted on the first external substrate; and a second connector and a second external substrate; and a second cap to be attached to the second connector to hold the second connector when it is reflow-mounted on the second external substrate formed of a material with a smaller thermal expansion coefficient than that of the external first substrate, wherein the first connector comprises: a first housing with a slot; and a plurality of contacts arranged in the slot, the first connector arranged in a direction orthogonal to an extending direction of the slot the second connector comprises a second housing with a header to be fitted in the slot, and a plurality of contacts arranged in a direction orthogonal to an extending direction of the header, wherein when the header is fitted into slots, the contacts of the first connector are electronically connected to the contacts of the second connector, characterised in that, the second cap is formed of a material with a smaller thermal expansion coefficient than that of the first cap. a first housing with a slot; and a plurality of contacts arranged in the slot, the first connector arranged in a direction orthogonal to an extending direction of the slot the second connector comprises a second housing with a header to be fitted in the slot, and a plurality of contacts arranged in a direction orthogonal to an extending direction of the header, wherein when the header is fitted into slots, the contacts of the first connector are electronically connected to the contacts of the second connector, characterised in that, the second cap is formed of a material with a smaller thermal expansion coefficient than that of the first cap.