An array substrate comprising: a base substrate; and a pixel define layer on the base substrate, the pixel define layer comprising a plurality of thickness thinning regions, wherein the thickness thinning regions have a smaller height than other areas of the pixel define layer on the base substrate, and the plurality of the thickness thinning regions are configured to guide flow of fillers to form an encapsulating layer on the pixel define layer; the pixel define layer comprises: a plurality of first spacing parts; and a plurality of second spacing parts intersecting the plurality of the first spacing parts, each of the plurality of the second spacing parts comprising a plurality of second spacing sub-parts, wherein a height of each of the plurality of the second spacing sub-parts is smaller than that of each of the plurality of the first spacing parts, and each of the thickness thinning regions comprises a plurality of the second spacing sub-parts between two adjacent first spacing parts; each of the plurality of the first spacing parts has a rectangular strip shape, a length direction of the first spacing parts is a first direction (a), and the plurality of the first spacing parts are distributed at intervals in a second direction (b); and the pixel define layer defines a plurality of pixel grids arranged in an array, and at least some of the pixel grids are located between two adjacent second spacing parts, wherein heights of the plurality of the second spacing sub-parts in a same thickness thinning region gradually decrease or increase along the first direction (a). a base substrate; and a pixel define layer on the base substrate, the pixel define layer comprising a plurality of thickness thinning regions, wherein the thickness thinning regions have a smaller height than other areas of the pixel define layer on the base substrate, and the plurality of the thickness thinning regions are configured to guide flow of fillers to form an encapsulating layer on the pixel define layer; the pixel define layer comprises: a plurality of first spacing parts; and a plurality of second spacing parts intersecting the plurality of the first spacing parts, each of the plurality of the second spacing parts comprising a plurality of second spacing sub-parts, wherein a height of each of the plurality of the second spacing sub-parts is smaller than that of each of the plurality of the first spacing parts, and each of the thickness thinning regions comprises a plurality of the second spacing sub-parts between two adjacent first spacing parts; each of the plurality of the first spacing parts has a rectangular strip shape, a length direction of the first spacing parts is a first direction (a), and the plurality of the first spacing parts are distributed at intervals in a second direction (b); and the pixel define layer defines a plurality of pixel grids arranged in an array, and at least some of the pixel grids are located between two adjacent second spacing parts, wherein heights of the plurality of the second spacing sub-parts in a same thickness thinning region gradually decrease or increase along the first direction (a). a plurality of first spacing parts; and a plurality of second spacing parts intersecting the plurality of the first spacing parts, each of the plurality of the second spacing parts comprising a plurality of second spacing sub-parts, wherein a height of each of the plurality of the second spacing sub-parts is smaller than that of each of the plurality of the first spacing parts, and each of the thickness thinning regions comprises a plurality of the second spacing sub-parts between two adjacent first spacing parts; each of the plurality of the first spacing parts has a rectangular strip shape, a length direction of the first spacing parts is a first direction (a), and the plurality of the first spacing parts are distributed at intervals in a second direction (b); and the pixel define layer defines a plurality of pixel grids arranged in an array, and at least some of the pixel grids are located between two adjacent second spacing parts, wherein heights of the plurality of the second spacing sub-parts in a same thickness thinning region gradually decrease or increase along the first direction (a).