An optical tomography imaging system for detecting peripheral artery disease, comprising: a controller configured to control an external body part stimulator, the external body part stimulator applying a mechanical stimulus to a target body part to be inspected; an interfacing module adapted for control by the controller and arranged to image a peripheral body part of the body part and employing, therefore, a plurality of light sources and a plurality of light detectors, the controller being configured to control each of the plurality of light sources to emit light sequentially such that light may be transmitted through the body part and transmitted light detected by the plurality of light detectors; the controller being configured to generate a tomographic image from detection signals generated by the plurality of light detectors; and the controller being further configured to apply a first mechanical stimulus while acquiring a first series of time separated data from the light detected by the light detectors and to later apply a second mechanical stimulus while acquiring a second series of time separated data from the light detected by the light detectors; the controller further being configured to generate and display visual representations derived from the first and second time series of time separated data thereby displaying a representation of a differential response of the body part to the first and second mechanical stimuli, characterized in that, the interfacing module is cylindrical in shape and is adjustable in the axial and radial dimensions to accommodate different body part shapes and sizes, the light sources and the light detectors of the interfacing module are positioned in a plurality of ring-like rows, and the interfacing module comprises connecting means configured to permit said ring-like rows including the light sources and light detectors to be moved relative to each other to change the mutual spacing of the ring-like rows. a controller configured to control an external body part stimulator, the external body part stimulator applying a mechanical stimulus to a target body part to be inspected; an interfacing module adapted for control by the controller and arranged to image a peripheral body part of the body part and employing, therefore, a plurality of light sources and a plurality of light detectors, the controller being configured to control each of the plurality of light sources to emit light sequentially such that light may be transmitted through the body part and transmitted light detected by the plurality of light detectors; the controller being configured to generate a tomographic image from detection signals generated by the plurality of light detectors; and the controller being further configured to apply a first mechanical stimulus while acquiring a first series of time separated data from the light detected by the light detectors and to later apply a second mechanical stimulus while acquiring a second series of time separated data from the light detected by the light detectors; the controller further being configured to generate and display visual representations derived from the first and second time series of time separated data thereby displaying a representation of a differential response of the body part to the first and second mechanical stimuli, characterized in that, the interfacing module is cylindrical in shape and is adjustable in the axial and radial dimensions to accommodate different body part shapes and sizes, the light sources and the light detectors of the interfacing module are positioned in a plurality of ring-like rows, and the interfacing module comprises connecting means configured to permit said ring-like rows including the light sources and light detectors to be moved relative to each other to change the mutual spacing of the ring-like rows.