mhurhangee/ep-ind-claims huggingface dataset:
Load-bearing and fastening bush for fastening a load to a supporting component, wherein the load-bearing and fastening bush is designed as an elongate body with an inner cavity which has a first opening at least at an end face of the elongate body, wherein an internal thread is provided in the inner cavity and extends at least over a part of the longitudinal extent of the inner cavity, and wherein the inner cavity is configured to either receive a screw thread of a load-bearing and fastening means (30, 32) which has threaded screw (34, 37), and the threaded screw (34, 37) of said means can be screwed into the internal thread, or a load-bearing and fastening means (20, 31) which has a ball retaining bolt, wherein the inner cavity has a contact edge directed away from the first opening in order to fasten the ball retaining bolt in a load-bearing manner, with the result that the balls of the ball retaining bolt can be placed behind the contact edge, as viewed from the first opening, when the bolt portion of the ball retaining bolt is inserted into the inner cavity, characterized in that the inner cavity has an internal thread-free portion at least over a part of its longitudinal extent, wherein the internal thread-free portion is arranged between the contact edge and the portion of the inner cavity that is provided with the internal thread and extends from the contact edge as far as the portion provided with the internal thread, wherein the internal thread-free portion has a locating bore or is designed as a locating bore of which the inside diameter is dimensioned with consideration to a maximum permissible play for ball retaining bolts, wherein a region surrounding the locating bore forms the contact edge, or characterized in that an inner thread portion (9, 40) is arranged in the inner cavity on each side of the internal thread-free portion.
A process for culturing cells by a) generating a solid form of a cell culture medium comprising at least one cell culture media ingredient by using 3D printing technologies b) mixing said solid form with a liquid and the cells to be cultured, thereby dissolving the solid form c) performing cell culture by incubating the mixture of step b) a) generating a solid form of a cell culture medium comprising at least one cell culture media ingredient by using 3D printing technologies b) mixing said solid form with a liquid and the cells to be cultured, thereby dissolving the solid form c) performing cell culture by incubating the mixture of step b)
A method of diagnosing hepatocellular carcinoma in a subject in need thereof, the method comprising: (a) determining the levels of laminin gamma 2 monomer and one or both of protein induced vitamin K antagonist-II (PIVKA-II) and alpha fetoprotein in a biological sample obtained from the subject; (b) comparing the level of laminin gamma 2 monomer and one or both of PIVKA-II and AFP to reference levels of laminin gamma 2 monomer, PIVKA-II and/or AFP, respectively; and (c) identifying the subject as having HCC when the levels of laminin gamma 2 monomer and one or both of PIVKA-II and AFP are greater than the reference levels of laminin gamma 2 monomer PIVKA-II and/or AFP, respectively. (a) determining the levels of laminin gamma 2 monomer and one or both of protein induced vitamin K antagonist-II (PIVKA-II) and alpha fetoprotein in a biological sample obtained from the subject; (b) comparing the level of laminin gamma 2 monomer and one or both of PIVKA-II and AFP to reference levels of laminin gamma 2 monomer, PIVKA-II and/or AFP, respectively; and (c) identifying the subject as having HCC when the levels of laminin gamma 2 monomer and one or both of PIVKA-II and AFP are greater than the reference levels of laminin gamma 2 monomer PIVKA-II and/or AFP, respectively.
A peptide that increases the level of estrogen in vitro or in vivo, wherein the peptide is an isolated or substantially pure polypeptide obtainable from Dioscorea sp., wherein the polypeptide has an apparent molecular weight of about 32.5 kDA by chromatography, wherein the first twenty-one consecutive amino acids at the N-terminal of the polypeptide consist of SEQ ID NO:1.
Assembly comprising a tubular foundation element, in particular a pile e.g. a jacket pile, to be installed in a ground formation, a pile driver and an anvil, the tubular foundation element having at least one open end, allowing the pile driver with the anvil to be inserted into the tubular foundation element, wherein the tubular foundation element has two open ends, wherein the tubular foundation element comprises a support at the inside thereof, wherein the support is adapted to transmit energy from the anvil directly to the tubular foundation element, during installation of the tubular foundation element, wherein the anvil and the support are configured such that during installation of the tubular foundation element to a position in which the tubular foundation element extends a distance above the surface of the ground formation the distance being for example 1.5 m, soil material that enters the tubular foundation element below the anvil and the support is directly compressed by both the anvil and the support, wherein the anvil and the support are configured such that the part of the tubular foundation element above the support after such installation of the tubular foundation element contains no or little soil material. a tubular foundation element, in particular a pile e.g. a jacket pile, to be installed in a ground formation, a pile driver and an anvil, the tubular foundation element having at least one open end, allowing the pile driver with the anvil to be inserted into the tubular foundation element, wherein the tubular foundation element has two open ends, wherein the tubular foundation element comprises a support at the inside thereof, wherein the support is adapted to transmit energy from the anvil directly to the tubular foundation element, during installation of the tubular foundation element, wherein the anvil and the support are configured such that during installation of the tubular foundation element to a position in which the tubular foundation element extends a distance above the surface of the ground formation the distance being for example 1.5 m, soil material that enters the tubular foundation element below the anvil and the support is directly compressed by both the anvil and the support, wherein the anvil and the support are configured such that the part of the tubular foundation element above the support after such installation of the tubular foundation element contains no or little soil material.
Flue terminal intended to connect an enclosed space to a discharge area by passing through a separation element, the terminal providing an air supply and discharge by means of two concentric ducts (23, 27), an outer duct and an inner duct, one end of the inner duct protruding outside the outer duct at one end located in the discharge area; the end of the terminal comprising: - a fastening ring designed to be secured to the outer duct; - a cowl comprising a central opening, designed to be secured to said end of the inner duct; - a partition connecting the fastening ring to the cowl and comprising openings designed to let the air pass between the outer duct and the inner duct; - a turbulator in a helical arrangement, designed to cause turbulence in the gases exiting from the terminal, housed in the inner duct; and - a clamping ring adjusting concentrically around the outer duct, said clamping ring being fixed to one wall of the separation element located in the enclosed space. - a fastening ring designed to be secured to the outer duct; - a cowl comprising a central opening, designed to be secured to said end of the inner duct; - a partition connecting the fastening ring to the cowl and comprising openings designed to let the air pass between the outer duct and the inner duct; - a turbulator in a helical arrangement, designed to cause turbulence in the gases exiting from the terminal, housed in the inner duct; and - a clamping ring adjusting concentrically around the outer duct, said clamping ring being fixed to one wall of the separation element located in the enclosed space.
An apparatus for measuring and treating dysphagia comprising: at least one dysphagia measurement sensor unit configured to be attached to a neck of a patient, at least one electrical stimulation electrode unit configured to be attached to the neck of the patient and applying electrical stimulation to the neck of the patient according to a dysphagia signal measured in the dysphagia measurement sensor unit to resolve dysphagia, and a control unit controlling the dysphagia measurement sensor unit and the electrical stimulation electrode unit, characterized in that the dysphagia measurement sensor unit includes an ultrasonic wave transmitting unit and an ultrasonic wave receiving unit, and the apparatus further comprises a ultrasonic wave sound absorption unit disposed between the ultrasonic wave transmitting unit and the ultrasonic wave receiving unit. at least one dysphagia measurement sensor unit configured to be attached to a neck of a patient, at least one electrical stimulation electrode unit configured to be attached to the neck of the patient and applying electrical stimulation to the neck of the patient according to a dysphagia signal measured in the dysphagia measurement sensor unit to resolve dysphagia, and a control unit controlling the dysphagia measurement sensor unit and the electrical stimulation electrode unit, characterized in that the dysphagia measurement sensor unit includes an ultrasonic wave transmitting unit and an ultrasonic wave receiving unit, and the apparatus further comprises a ultrasonic wave sound absorption unit disposed between the ultrasonic wave transmitting unit and the ultrasonic wave receiving unit.
A method of wireless communication, comprising: generating, by a base station, BS (110, 910, 1005, 1600, 1700), a first transmission layer of a multi-layer communication using a first waveform of a plurality of waveforms; generating, by the base station, BS (110, 910, 1005, 1600, 1700), a second transmission layer of the multi-layer communication using a second waveform of the plurality of waveforms, wherein the first waveform and the second waveform are different; and transmitting, by the base station, BS (110, 910, 1005, 1600, 1700), the first transmission layer and the second transmission layer using a same time resource and a same frequency resource, wherein the first transmission layer is transmitted using the first waveform and the second transmission layer is transmitted using the second waveform. generating, by a base station, BS (110, 910, 1005, 1600, 1700), a first transmission layer of a multi-layer communication using a first waveform of a plurality of waveforms; generating, by the base station, BS (110, 910, 1005, 1600, 1700), a second transmission layer of the multi-layer communication using a second waveform of the plurality of waveforms, wherein the first waveform and the second waveform are different; and transmitting, by the base station, BS (110, 910, 1005, 1600, 1700), the first transmission layer and the second transmission layer using a same time resource and a same frequency resource, wherein the first transmission layer is transmitted using the first waveform and the second transmission layer is transmitted using the second waveform.
An apparatus for controlling a switch (103, 203, 303, 403, 503), the apparatus comprising: circuitry (105, 205, 305, 405, 505) configured to: detect a voltage across the switch; generate a current reference signal based on the voltage across the switch, the current reference signal being inversely proportional to the voltage across the switch; receive a feedback current signal representing a current level in the switch; and control the switch based on a difference between the current reference signal and the feedback current signal. detect a voltage across the switch; generate a current reference signal based on the voltage across the switch, the current reference signal being inversely proportional to the voltage across the switch; receive a feedback current signal representing a current level in the switch; and control the switch based on a difference between the current reference signal and the feedback current signal.
A compound having a structure according to formula I or a pharmaceutically acceptable salt thereof, wherein Xaa 1 is selected from the group consisting of iodo-substituted D- and L-Tyr or D- and L-Tyr, which is methyl-substituted at the aromatic ring, iodo-substituted or methyl-substituted D- and L- homotyrosine, iodo-substituted or methyl-substituted D- and L-Phe, iodo-substituted or methyl-substituted D- and L- p-OH-phenylglycine, and iodo-substituted or methyl-substituted D- or L- Trp; Xaa 2 is a natural or unnatural basic amino acid, Xaa 3 is an optionally N-alkylated natural or unnatural amino acid, Xaa 4 is glycine or a D-amino acid, R is H or methyl, L is a linker moiety Ar is a spacer comprising an aromatic moiety and D comprises, preferably is i) a combination of an organic complexation agent and a radioactive, or non-radioactive metal, or detectable label; or ii) a radioactive or detectable label, an organic complexation agent or an active substance, said active substance particularly being selected from cytotoxic agents, lipids, sugars, sugar conjugates, sugar derivatives, proteins and combinations thereof. wherein Xaa 1 is selected from the group consisting of iodo-substituted D- and L-Tyr or D- and L-Tyr, which is methyl-substituted at the aromatic ring, iodo-substituted or methyl-substituted D- and L- homotyrosine, iodo-substituted or methyl-substituted D- and L-Phe, iodo-substituted or methyl-substituted D- and L- p-OH-phenylglycine, and iodo-substituted or methyl-substituted D- or L- Trp; Xaa 2 is a natural or unnatural basic amino acid, Xaa 3 is an optionally N-alkylated natural or unnatural amino acid, Xaa 4 is glycine or a D-amino acid, R is H or methyl, L is a linker moiety Ar is a spacer comprising an aromatic moiety and D comprises, preferably is i) a combination of an organic complexation agent and a radioactive, or non-radioactive metal, or detectable label; or ii) a radioactive or detectable label, an organic complexation agent or an active substance, said active substance particularly being selected from cytotoxic agents, lipids, sugars, sugar conjugates, sugar derivatives, proteins and combinations thereof. i) a combination of an organic complexation agent and a radioactive, or non-radioactive metal, or detectable label; or ii) a radioactive or detectable label, an organic complexation agent or an active substance, said active substance particularly being selected from cytotoxic agents, lipids, sugars, sugar conjugates, sugar derivatives, proteins and combinations thereof.
Shaving unit, comprising: - at least one hair-cutting unit comprising an external cutting member having hair-entry openings in a cutting track surface and an internal cutting member having at least one hair-cutting element and being movable relative to the external cutting member; - a base member supporting the at least one hair-cutting unit; and - at least one skin-heating unit comprising at least one infrared or near-infrared light source arranged to emit infrared or near-infrared light; characterized in that: the at least one skin-heating unit comprises a skin-contacting member having a skin-contacting surface arranged adjacent to the at least one hair-cutting unit to contact the skin during use of the shaving unit; and the at least one infrared or near-infrared light source is integrated in the skin-contacting member, thermally coupled to the skin-contacting surface and arranged to emit the infrared or near-infrared light via the skin-contacting surface. - at least one hair-cutting unit comprising an external cutting member having hair-entry openings in a cutting track surface and an internal cutting member having at least one hair-cutting element and being movable relative to the external cutting member; - a base member supporting the at least one hair-cutting unit; and - at least one skin-heating unit comprising at least one infrared or near-infrared light source arranged to emit infrared or near-infrared light; the at least one skin-heating unit comprises a skin-contacting member having a skin-contacting surface arranged adjacent to the at least one hair-cutting unit to contact the skin during use of the shaving unit; and the at least one infrared or near-infrared light source is integrated in the skin-contacting member, thermally coupled to the skin-contacting surface and arranged to emit the infrared or near-infrared light via the skin-contacting surface.
A method of reducing glycoprotein aggregation comprising eliminating one or more O-linked glycosylation sites therein, wherein the glycoprotein comprises the hinge region of a Fc domain and wherein the O-linked glycosylation sites to be eliminated are in said hinge region.
A belt retractor comprising a frame provided with locking teeth, a belt reel which is rotatably supported in the frame and is provided on at least one axial end with ratchet teeth adapted to engage in the locking teeth when the belt reel is adjusted from a home position into a locking position, a blocking bearing interacting with the belt reel on the side on which the ratchet teeth are arranged and retaining the latter in the home position up to a first load threshold, and a load bearing interacting with the belt reel on the opposite side and retaining the latter in the home position up to a second load threshold, wherein the first load threshold is below the second load threshold, characterized in that a control mechanism is provided which is adapted to shift the belt reel from a home position into a locking position in which the locking teeth are engaged in the ratchet teeth. and in that the control mechanism includes a control lever pivoted on the frame side which acts on the blocking bearing and is adapted to shift the belt reel into the locking position.
An electric latch for a motor vehicle foldable seat, located inside a case, said latch comprising: - a locking means adapted to move between a position in which a striker is retained and a position in which said striker is released, - a blocking member adapted to move between a position for blocking the locking means in said striker retaining position and a position for clearing the way with respect to the displacement of the locking means - a transmission lever secured to the blocking member so as to displace it between said position for blocking the locking means in the striker retaining position and said cleared position with respect to the displacement of the locking means, - an actuator including an electric motor, said actuator being adapted to displace said transmission lever, characterized in that said transmission lever moves about an axis of rotation and has two arms (11,12) extending radially from the axis, the first arm having at its end a handle for manually displacing the transmission lever and the second arm having at its end a means for securing with the blocking element. - a locking means adapted to move between a position in which a striker is retained and a position in which said striker is released, - a blocking member adapted to move between a position for blocking the locking means in said striker retaining position and a position for clearing the way with respect to the displacement of the locking means - a transmission lever secured to the blocking member so as to displace it between said position for blocking the locking means in the striker retaining position and said cleared position with respect to the displacement of the locking means, - an actuator including an electric motor, said actuator being adapted to displace said transmission lever,
A process for preparing substituted 2-methylaminopyridine derivatives of the formula and corresponding salts thereof, wherein p is an integer equal to 1 or 2, X is independently of the others, as being fluorine, chlorine, or difluoromethyl, trifluoromethyl, dichloromethyl, trichloromethyl; and the 2-pyridyl moiety is substituted by X in 3- and/or in 5-position, characterized in that in step a substituted cyanopyridyl derivative according to formula wherein p is 1 or 2; X is independently of the others, as being fluorine, chlorine, or difluoromethyl, trifluoromethyl, dichloromethyl, trichloromethyl; and the 2-pyridyl moiety is substituted by X in 3- and/or in 5-position, is hydrogenated in the presence of a metal catalyst, wherein the metal catalyst is selected from the group of palladium, platinum, ruthenium, and rhodium catalysts, a catalyst modifier, wherein the catalyst modifier is selected from the group of n-tetramethylammonium bromide (TMAB), n-tetrabutylammoniumbromide (TBAB) and an acid wherein the the concentration of the catalyst modifier is in the range from about 0.0000001 equivalents to about 10 equivalents with respect to the amount of cyanopyridyl derivative according to formula. X is independently of the others, as being fluorine, chlorine, or difluoromethyl, trifluoromethyl, dichloromethyl, trichloromethyl; and the 2-pyridyl moiety is substituted by X in 3- and/or in 5-position, characterized in that in step a substituted cyanopyridyl derivative according to formula X is independently of the others, as being fluorine, chlorine, or difluoromethyl, trifluoromethyl, dichloromethyl, trichloromethyl; and the 2-pyridyl moiety is substituted by X in 3- and/or in 5-position, is hydrogenated in the presence of a metal catalyst, wherein the metal catalyst is selected from the group of palladium, platinum, ruthenium, and rhodium catalysts, a catalyst modifier, wherein the catalyst modifier is selected from the group of n-tetramethylammonium bromide (TMAB), n-tetrabutylammoniumbromide (TBAB) and an acid wherein the the concentration of the catalyst modifier is in the range from about 0.0000001 equivalents to about 10 equivalents with respect to the amount of cyanopyridyl derivative according to formula.
Wing anti-collision strobe light unit for an aircraft comprising: at least one light source, particularly at least one LED; a reflector element, the at least one light source and the reflector element being configured for projecting light into a desired range of directions; and a stray light blocking element for blocking stray light from being projected into undesired directions, the stray light blocking element attached to the reflector element or to a base portion of the strobe light unit, the stray light blocking element comprising a substantially planar main portion, characterized in that the substantially planar main portion extends into a radial direction from the at least one light source, such that parallel and/or radial light beams projected into the desired range of directions are substantially unaffected by the stray light blocking element and such that stray light beams of an undesired range of directions, particularly stray light beams reflected by an additional transparent cover or an additional cover lens, are blocked. at least one light source, particularly at least one LED; a reflector element, the at least one light source and the reflector element being configured for projecting light into a desired range of directions; and a stray light blocking element for blocking stray light from being projected into undesired directions, the stray light blocking element attached to the reflector element or to a base portion of the strobe light unit, the stray light blocking element comprising a substantially planar main portion, characterized in that the substantially planar main portion extends into a radial direction from the at least one light source, such that parallel and/or radial light beams projected into the desired range of directions are substantially unaffected by the stray light blocking element and such that stray light beams of an undesired range of directions, particularly stray light beams reflected by an additional transparent cover or an additional cover lens, are blocked.