mhurhangee/ep-ind-claims huggingface dataset:
A method for the quantitative determination of an impurity present in a peptide product composition, comprising the steps: (a) providing a peptide product composition comprising a peptide product, which is an exendin peptide product comprising the amino acid sequence S-S-G-A and an unknown amount of at least one impurity which is a Di-Ser -exendin peptide and/or a Di-Ala -exendin peptide and which differs from the desired peptide product by a dimeric amino acid building block of Di-serine and/or Di-alanine, wherein said impurity cannot be separated from the peptide product or another ingredient of the composition by a chromatographic procedure and wherein said impurity co-elutes or substantially co-elutes with the desired peptide product after the chromatographic separation procedure, (b) providing at least one sample of the peptide product composition without said impurity added and at least one further sample of the peptide product composition with a known amount of said impurity added, (c) quantitatively determining said impurity in said sample from step (b) by mass spectrometry, and (d) calculating the amount of said impurity in the peptide product composition based on the results of (c). (a) providing a peptide product composition comprising a peptide product, which is an exendin peptide product comprising the amino acid sequence S-S-G-A and an unknown amount of at least one impurity which is a Di-Ser -exendin peptide and/or a Di-Ala -exendin peptide and which differs from the desired peptide product by a dimeric amino acid building block of Di-serine and/or Di-alanine, wherein said impurity cannot be separated from the peptide product or another ingredient of the composition by a chromatographic procedure and wherein said impurity co-elutes or substantially co-elutes with the desired peptide product after the chromatographic separation procedure, (b) providing at least one sample of the peptide product composition without said impurity added and at least one further sample of the peptide product composition with a known amount of said impurity added, (c) quantitatively determining said impurity in said sample from step (b) by mass spectrometry, and (d) calculating the amount of said impurity in the peptide product composition based on the results of (c).
A seal assembly (20, 22) for a gas turbine engine, comprising: a seal (26, 34) comprising a carbon material; and a seal seat (24, 32) positioned for rotation relative to the seal (26, 34), wherein the seal (26, 34) and the seal seat (24, 32) each have a sealing surface (28, 30, 36, 38) which together define a sliding seal, and wherein at least the sealing surface (30, 36) of the seal seat (24, 32) is made of the same carbon material as the sealing surface (28, 38) of the seal (26, 34), characterized in that: only the seal seat (24, 32) has a receptacle and a carbon-based block mounted in the receptacle, the carbon-based block defining the sealing surface (30, 36) of the seal seat (24, 32). a seal (26, 34) comprising a carbon material; and a seal seat (24, 32) positioned for rotation relative to the seal (26, 34), wherein the seal (26, 34) and the seal seat (24, 32) each have a sealing surface (28, 30, 36, 38) which together define a sliding seal, and wherein at least the sealing surface (30, 36) of the seal seat (24, 32) is made of the same carbon material as the sealing surface (28, 38) of the seal (26, 34), characterized in that: only the seal seat (24, 32) has a receptacle and a carbon-based block mounted in the receptacle, the carbon-based block defining the sealing surface (30, 36) of the seal seat (24, 32).
A method for replacing the operating software of a limited-resource portable data carrier at a terminal, wherein the operating software controls the operation of the data carrier and executes at least one function provided by the data carrier, and wherein an authentication of the terminal to the data carrier is carried out, with the steps: - providing a new operating software in the terminal, - providing a bootstrap loader for loading new operating software in the data carrier, - providing a terminal certificate in the terminal, which proves the authorization for the transmission of a loading key, - transmitting the terminal certificate to the data carrier within the framework of the authentication of the terminal, - verifying the terminal certificate by the data carrier, - transmitting a loading key to the data carrier, - transferring the operation control of the data carrier to the bootstrap loader, - deleting the operating software of the data carrier by the bootstrap loader, - transmitting the new operating software to the data carrier using the loading key, - activating the new operating software by the bootstrap loader, - transferring the control of the data carrier from the bootstrap loader to the new operating software. - providing a new operating software in the terminal, - providing a bootstrap loader for loading new operating software in the data carrier, - providing a terminal certificate in the terminal, which proves the authorization for the transmission of a loading key, - transmitting the terminal certificate to the data carrier within the framework of the authentication of the terminal, - verifying the terminal certificate by the data carrier, - transmitting a loading key to the data carrier, - transferring the operation control of the data carrier to the bootstrap loader, - deleting the operating software of the data carrier by the bootstrap loader, - transmitting the new operating software to the data carrier using the loading key, - activating the new operating software by the bootstrap loader, - transferring the control of the data carrier from the bootstrap loader to the new operating software.
A baby carrier comprising chest straps, which are arranged to extend around both shoulder regions of a wearer, a waist belt, and a baby-carrying pouch mounted on the chest straps and the waist belt, said baby-carrying pouch comprises at least a front piece having leg openings and a head support, respective lateral corner of the head support being detachably connected to corresponding nearby connecting point at respective chest strap by a first strap means having a detachable buckle, characterized in that a second strap means is arranged between respective lateral corner of the head support and a buckle slidably arranged along respective first strap means, and that said second strap means is continuously adjustably connected to said buckle.
A case for a mobile device, the case comprising: a flexible covering defining a cavity configured for receiving and holding the mobile device; a rigid frame at least partially disposed within the flexible covering, wherein at least one first portion of the rigid frame is covered on one of two opposing sides by the flexible covering and exposed on another of the two opposing sides, at least one second portion of the rigid frame is exposed on both of the two opposing sides, and at least one third portion of the rigid frame is covered on both of the two opposing sides by the flexible covering; and an adapter disposed at least partially within the rigid frame and the flexible covering, the adapter comprising a plurality of first contacts for coupling to contacts of an external device, a male plug extending into the cavity defined by the flexible covering and configured for insertion into a female socket of the mobile device, and a plurality of second contacts disposed on the male plug and electrically coupled to the first contacts of the adapter; wherein the adapter, in combination with at least one of the flexible covering or the rigid frame, defines a first male structure extending away from the cavity defined by the flexible covering of the case and configured for coupling to the external device, wherein the first contacts of the adapter are disposed on the first male structure. a flexible covering defining a cavity configured for receiving and holding the mobile device; a rigid frame at least partially disposed within the flexible covering, wherein at least one first portion of the rigid frame is covered on one of two opposing sides by the flexible covering and exposed on another of the two opposing sides, at least one second portion of the rigid frame is exposed on both of the two opposing sides, and at least one third portion of the rigid frame is covered on both of the two opposing sides by the flexible covering; and an adapter disposed at least partially within the rigid frame and the flexible covering, the adapter comprising a plurality of first contacts for coupling to contacts of an external device, a male plug extending into the cavity defined by the flexible covering and configured for insertion into a female socket of the mobile device, and a plurality of second contacts disposed on the male plug and electrically coupled to the first contacts of the adapter; wherein the adapter, in combination with at least one of the flexible covering or the rigid frame, defines a first male structure extending away from the cavity defined by the flexible covering of the case and configured for coupling to the external device, wherein the first contacts of the adapter are disposed on the first male structure.
Freight loading system for loading and unloading a freight deck, comprising: - at least one freight reading device mounted in the entry area of the aeroplane for detecting at least one identifier of an item of freight; - a plurality of freight conveying means (100, 110,..., 210), each having at least one roller (102a, 102b) for conveying the item of freight along a conveying route into an end position, - a plurality of sensors (104a, 104b, 104c, 104d), - a control unit which receives signals from the sensors (104a, 104b, 104c, 104d) in order to detect a movement of the item of freight along the conveying route based on a changing overlap pattern, and is in communicative coupling with the freight reading device, wherein the overlap pattern indicates which freight conveying means are overlapped by the item of freight, wherein the control unit is configured to detect the end position of the item of freight on the freight deck based on the signals and to store data indicating the end position in conjunction with the identifier of the item of freight detected in the entry area, wherein a position is then detected as an end position and is stored in conjunction with the detected identifier when the overlap pattern does not change any more. - at least one freight reading device mounted in the entry area of the aeroplane for detecting at least one identifier of an item of freight; - a plurality of freight conveying means (100, 110,..., 210), each having at least one roller (102a, 102b) for conveying the item of freight along a conveying route into an end position, - a plurality of sensors (104a, 104b, 104c, 104d), - a control unit which receives signals from the sensors (104a, 104b, 104c, 104d) in order to detect a movement of the item of freight along the conveying route based on a changing overlap pattern, and is in communicative coupling with the freight reading device, wherein the overlap pattern indicates which freight conveying means are overlapped by the item of freight,
A method, comprising: a third computing device (KMSO), configured to perform a key management function according to MIKEY-TICKET method and having a pre-existing security association with a first computing device (KMS I) and a pre-existing security association with a second computing device (KMS R), the first computing device (KMS I) and the second computing device (KMS R) not having a pre-existing security association there-between, receives a request from one of the first computing device (KMS I) and the second computing device (KMS R); wherein the first computing device (KMS I) is configured to perform a key management function for a first user equipment (UE I) according to MIKEY-TICKET method; wherein the second computing device (KMS R) is configured to perform a key management function for a second user equipment (UE R) according to MIKEY-TICKET method; wherein the first, second and third computing device (KMSO, KMS I, KMS R), and the first and second user equipments (UE I, UE R) are in a communication system, wherein in response to the request, the third computing device (KMSO) facilitates establishment of a security association between the first computing device (KMS I) and the second computing device (KMSR); and the first computing device (KMS I) and the second computing device (KMS R) then facilitate establishment of a security association between the first user equipment (UE I) and the second user equipment (UE R). a third computing device (KMSO), configured to perform a key management function according to MIKEY-TICKET method and having a pre-existing security association with a first computing device (KMS I) and a pre-existing security association with a second computing device (KMS R), the first computing device (KMS I) and the second computing device (KMS R) not having a pre-existing security association there-between, receives a request from one of the first computing device (KMS I) and the second computing device (KMS R); wherein the first computing device (KMS I) is configured to perform a key management function for a first user equipment (UE I) according to MIKEY-TICKET method; wherein the second computing device (KMS R) is configured to perform a key management function for a second user equipment (UE R) according to MIKEY-TICKET method; wherein the first, second and third computing device (KMSO, KMS I, KMS R), and the first and second user equipments (UE I, UE R) are in a communication system, wherein in response to the request, the third computing device (KMSO) facilitates establishment of a security association between the first computing device (KMS I) and the second computing device (KMSR); and the first computing device (KMS I) and the second computing device (KMS R) then facilitate establishment of a security association between the first user equipment (UE I) and the second user equipment (UE R).
A device for delivering nasal medication, having: - an ultrasonic energy generator, being a concave ultrasonic transducer, adapted to create an ultrasonic focal zone of concentrated ultrasonic energy; - a feeder chamber holding medication; - an energising chamber smaller than the feeder chamber, arranged to hold medication at the focal zone; - a mesh; and - a nasal prong; the device formed so that when it is activated: - the feeder chamber continuously fills the energising chamber with medication, until the feeder chamber has insufficient medication left to achieve this, so that there is a substantially constant supply of medication within the focal zone able to be energised and forced from the energising chamber so as to contact the mesh, become an aerosol, and leave the device by way of the prong. - an ultrasonic energy generator, being a concave ultrasonic transducer, adapted to create an ultrasonic focal zone of concentrated ultrasonic energy; - a feeder chamber holding medication; - an energising chamber smaller than the feeder chamber, arranged to hold medication at the focal zone; - a mesh; and - a nasal prong; - the feeder chamber continuously fills the energising chamber with medication, until the feeder chamber has insufficient medication left to achieve this, so that there is a substantially constant supply of medication within the focal zone able to be energised and forced from the energising chamber so as to contact the mesh, become an aerosol, and leave the device by way of the prong.
Machine for producing and dispensing products such as ice cream, frozen beverages or granita, comprising a product-containing lank which is provided with a tap for dispensing the product and inside which there projects from a rear wall a cylinder which has a substantially horizontal axis and which forms the evaporator of a refrigerating circuit of the machine for cooling the product in the tank, a mixer element for stirring the product being present around the cylinder so as to rotate coaxially with the axis of the cylinder by means of a motor unit, which is arranged outside the tank and which rotates the mixer element by means of a drive shaft with an axis which passes along the axis of the cylinder and which is connected to the mixer element at one end of the cylinder which is opposite to the said rear wall, characterized in that the motor unit comprises a final reduction stage arranged coaxial with said drive shaft and an electric motor which projects laterally with its axis substantially transverse to the axis of the drive shaft, the final reduction stage and motor being interconnected by means of an angular transmission stage, and in that the motor unit is at least partially housed inside the cylinder through the said rear wall.
A method for producing a laser arrangement (200; 300) including a submount (201, 301), said method comprising: - providing a submount (201;301) with a recess (202, 302); - providing at least one Vertical-Cavity Surface-Emitting Laser or VCSEL (203, 303) in the recess (202; 302); - depositing metal connections (204; 304) extending between an upper surface of said at least one VCSEL (203, 303) and an upper surface of said submount (201; 301), wherein said recess (202; 302) is dimensioned to hold said at least one VCSEL (203; 303) such that said metal connections (204; 304) are substantially flat; and - providing a planar waveguide light coupling device at a distance of at most 30 micrometers from a light emitting surface of said at least one VCSEL (203,303), wherein said step of depositing metal connections (204; 304) comprises a plating technique or a lift-off technique. - providing a submount (201;301) with a recess (202, 302); - providing at least one Vertical-Cavity Surface-Emitting Laser or VCSEL (203, 303) in the recess (202; 302); - depositing metal connections (204; 304) extending between an upper surface of said at least one VCSEL (203, 303) and an upper surface of said submount (201; 301), wherein said recess (202; 302) is dimensioned to hold said at least one VCSEL (203; 303) such that said metal connections (204; 304) are substantially flat; and - providing a planar waveguide light coupling device at a distance of at most 30 micrometers from a light emitting surface of said at least one VCSEL (203,303),
A cathode assembly suitable for a Hall-Heroult electrolysis cell, comprising - a cathode body (1,2) made of a carbonaceous material; - at least one cathode bar (3,3',4,4') made of a first conductive material, said cathode bar (3,3',4,4') being fitted in a groove provided in said cathode body (1,2); - at least an insert (5,5',6,6') made of a second conductive material, having a higher electrical conductivity than that of said first conductive material, said insert (5,5',6,6') being fitted in a slot or bore provided in said cathode bar (3,3',4,4'); characterized in that said insert (5,5',6,6') has at least one first so-called electrically conductive region and at least one second so-called electrically non-conductive region, the electrically conductive contact peripheral length of said insert with said cathode body (1,2) and/or said cathode bar (3,3',4,4') being superior in the first region than in the second region, the peripheral contact length of the insert being the sum of the lengths of its sides, in cross section, which contact the cathode bar and/or the cathode body. - a cathode body (1,2) made of a carbonaceous material; - at least one cathode bar (3,3',4,4') made of a first conductive material, said cathode bar (3,3',4,4') being fitted in a groove provided in said cathode body (1,2); - at least an insert (5,5',6,6') made of a second conductive material, having a higher electrical conductivity than that of said first conductive material, said insert (5,5',6,6') being fitted in a slot or bore provided in said cathode bar (3,3',4,4');
An isolated polynucleotide comprising a nucleotide sequence at least 95% identical to a sequence selected from the group consisting of: (a) a nucleotide sequence encoding a SLC34A2-ROS fusion polypeptide comprising the amino acid sequence of SEQ ID NO: 1 or SEQ ID NO: 3; (b) a nucleotide sequence encoding a SLC34A2-ROS fusion polypeptide, said nucleotide sequence comprising the nucleotide sequence of SEQ ID NO: 2 or SEQ ID NO: 4; (c) a nucleotide sequence encoding a SLC34A2-ROS fusion polypeptide comprising the N-terminal amino acid sequence of SLC34A2 which consists of residues 1-126 of SEQ ID NO: 5 and the kinase domain of ROS which consists of residues 1945-2222 of SEQ ID NO: 7; (d) a nucleotide sequence comprising the N-terminal nucleotide sequence of SLC34A2 which consists of nucleotides 1-378 of SEQ ID NO: 6 and the kinase domain nucleotide sequence of ROS which consists of nucleotides 6032-6865 of SEQ ID NO: 8; and (e) a nucleotide sequence complementary to any of the nucleotide sequences of (a)-(d). (a) a nucleotide sequence encoding a SLC34A2-ROS fusion polypeptide comprising the amino acid sequence of SEQ ID NO: 1 or SEQ ID NO: 3; (b) a nucleotide sequence encoding a SLC34A2-ROS fusion polypeptide, said nucleotide sequence comprising the nucleotide sequence of SEQ ID NO: 2 or SEQ ID NO: 4; (c) a nucleotide sequence encoding a SLC34A2-ROS fusion polypeptide comprising the N-terminal amino acid sequence of SLC34A2 which consists of residues 1-126 of SEQ ID NO: 5 and the kinase domain of ROS which consists of residues 1945-2222 of SEQ ID NO: 7; (d) a nucleotide sequence comprising the N-terminal nucleotide sequence of SLC34A2 which consists of nucleotides 1-378 of SEQ ID NO: 6 and the kinase domain nucleotide sequence of ROS which consists of nucleotides 6032-6865 of SEQ ID NO: 8; and (e) a nucleotide sequence complementary to any of the nucleotide sequences of (a)-(d).
An enzymatic detergent composition comprising the combination of: (i) a surfactant system; (ii) one or more enzymes; and (iii) one or more lignin compounds, wherein the surfactant system comprises a biosurfactant. (i) a surfactant system; (ii) one or more enzymes; and (iii) one or more lignin compounds, wherein the surfactant system comprises a biosurfactant.
A thermal transfer printer comprising: first and second spool supports (8, 12) each being configured to support a spool of ribbon; a ribbon drive configured to cause movement of ribbon from the first spool support to the second spool support; a printhead for selectively transferring ink from the ribbon to a substrate; and a motor coupled to the printhead via a flexible linkage, wherein the flexible linkage is a belt, the motor being arranged to vary the position of the printhead relative to a surface against which printing is carried out to thereby control the pressure exerted by the printhead on said surface; wherein the printhead is rotatable about a pivot (40, 40a) and the motor is arranged to cause rotation of the printhead about said pivot to vary said position of the printhead relative to said surface. first and second spool supports (8, 12) each being configured to support a spool of ribbon; a ribbon drive configured to cause movement of ribbon from the first spool support to the second spool support; a printhead for selectively transferring ink from the ribbon to a substrate; and a motor coupled to the printhead via a flexible linkage, wherein the flexible linkage is a belt, the motor being arranged to vary the position of the printhead relative to a surface against which printing is carried out to thereby control the pressure exerted by the printhead on said surface; wherein the printhead is rotatable about a pivot (40, 40a) and the motor is arranged to cause rotation of the printhead about said pivot to vary said position of the printhead relative to said surface.