A device for optoacoustic sensing, the device comprising an irradiation unit configured to generate at least one train of periodic pulses of electromagnetic energy, the pulses of the at least one train of periodic pulses exhibiting a predetermined pulse duration (t p) and repetition rate (r) and the at least one train of periodic pulses exhibiting a train duration, and to irradiate a target with the generated at least one train of periodic pulses, a detection unit configured to detect acoustic waves generated in the target in response to irradiating the target with the at least one train of periodic pulses and to generate an according detection signal, the detection signal comprising detection signal components at a plurality of discrete frequencies in the frequency domain, the discrete frequencies being spaced from each other by a frequency spacing corresponding to the predetermined repetition rate (r) of the pulses of the at least one train of periodic pulses, and a processing unit configured - to modify the detection signal in the frequency domain to obtain a modified detection signal, and - to derive at least one property of the target based on the modified detection signal, wherein the inverse of the product of the repetition rate (r) and the pulse duration (t p) of the pulses of the at least one train of periodic pulses of electromagnetic energy is at least 10, whereby the detection signal comprises discrete detection signal components at at least 10 discrete frequencies in the frequency domain, and characterised in that the processing unit is configured to modify the detection signal in the frequency domain by filtering the detection signal in the frequency domain by filtering out and/or suppressing and/or attenuating signal components of the detection signal at frequencies located between the plurality of discrete frequencies. the device comprising an irradiation unit configured to generate at least one train of periodic pulses of electromagnetic energy, the pulses of the at least one train of periodic pulses exhibiting a predetermined pulse duration (t p) and repetition rate (r) and the at least one train of periodic pulses exhibiting a train duration, and to irradiate a target with the generated at least one train of periodic pulses, a detection unit configured to detect acoustic waves generated in the target in response to irradiating the target with the at least one train of periodic pulses and to generate an according detection signal, the detection signal comprising detection signal components at a plurality of discrete frequencies in the frequency domain, the discrete frequencies being spaced from each other by a frequency spacing corresponding to the predetermined repetition rate (r) of the pulses of the at least one train of periodic pulses, and a processing unit configured - to modify the detection signal in the frequency domain to obtain a modified detection signal, and - to derive at least one property of the target based on the modified detection signal, - to modify the detection signal in the frequency domain to obtain a modified detection signal, and - to derive at least one property of the target based on the modified detection signal, wherein the inverse of the product of the repetition rate (r) and the pulse duration (t p) of the pulses of the at least one train of periodic pulses of electromagnetic energy is at least 10, whereby the detection signal comprises discrete detection signal components at at least 10 discrete frequencies in the frequency domain, and characterised in that the processing unit is configured to modify the detection signal in the frequency domain by filtering the detection signal in the frequency domain by filtering out and/or suppressing and/or attenuating signal components of the detection signal at frequencies located between the plurality of discrete frequencies.