mhurhangee/ep-ind-claims huggingface dataset:
A delivery device for percutaneously delivering a self-expanding prosthesis, the self-expanding prosthesis having a first end and a second end, the second end being proximal to the first end when the self-expanding prosthesis is loaded onto the delivery device, the delivery device comprising: a handle having at least one actuator thereon; a control release shaft having a proximal end operatively coupled to the handle and a distal end including a collar having a sloped distal edge, wherein the control release shaft is rotatable via actuation of the at least one actuator of the handle in order to rotate the collar; and a pusher shaft disposed within the control release shaft, the pusher shaft having a proximal end operatively coupled to the handle and a distal end having a spindle coupled thereto, the spindle being configured to receive at least one connector extending from at least one endmost crown of the self-expanding prosthesis in order to releasably attach the self-expanding prosthesis to the pusher shaft, wherein, when disposed over the second end of the self-expanding prosthesis, the collar is configured to radially restrain the endmost crowns and the at least one connector of the self-expanding prosthesis, and wherein actuation of the at least one actuator of the handle rotates and proximally retracts the collar relative to the spindle to achieve incremental release of the endmost crowns and the at least one connector of the self-expanding prosthesis. a handle having at least one actuator thereon; a control release shaft having a proximal end operatively coupled to the handle and a distal end including a collar having a sloped distal edge, wherein the control release shaft is rotatable via actuation of the at least one actuator of the handle in order to rotate the collar; and a pusher shaft disposed within the control release shaft, the pusher shaft having a proximal end operatively coupled to the handle and a distal end having a spindle coupled thereto, the spindle being configured to receive at least one connector extending from at least one endmost crown of the self-expanding prosthesis in order to releasably attach the self-expanding prosthesis to the pusher shaft, wherein, when disposed over the second end of the self-expanding prosthesis, the collar is configured to radially restrain the endmost crowns and the at least one connector of the self-expanding prosthesis, and wherein actuation of the at least one actuator of the handle rotates and proximally retracts the collar relative to the spindle to achieve incremental release of the endmost crowns and the at least one connector of the self-expanding prosthesis.
Nozzle with a nozzle surface area and a nozzle rim, on which first and second guiding devices (10, 20) are alternately provided in the circumferential direction, wherein - the first guiding devices are of the nozzle-type design, - the second guiding devices are of the diffuser-type design, - the first guiding devices each have a first azimuthal guide wall and two wall elements, with the first azimuthal guide wall forming a first trailing edge and two first edges to the wall elements, - the second guiding devices each have a second azimuthal guide wall and two wall elements, with the second azimuthal guide wall forming a second trailing edge and two second edges to the wall elements, and - a wall element connects a first guiding device to a second guiding device while forming part of both guiding devices (10, 20), with each wall element having a first edge to one of the first guide walls, a second edge diverging to the first edge in the axial direction to one of the second guide walls and a front-side trailing edge, wherein at least some of the first trailing edges of the first azimuthal guide walls and/ or at least some of the second trailing edges of the second azimuthal guide walls run obliquely to the circumferential direction, and by this at least some of the front-side trailing edges of adjacent wall elements (11, 21) have a different axial position, characterized in that the wall elements run obliquely with a radial component and a component in the circumferential direction, and/or the wall elements have a curved course in the axial direction. - the first guiding devices are of the nozzle-type design, - the second guiding devices are of the diffuser-type design, - the first guiding devices each have a first azimuthal guide wall and two wall elements, with the first azimuthal guide wall forming a first trailing edge and two first edges to the wall elements, - the second guiding devices each have a second azimuthal guide wall and two wall elements, with the second azimuthal guide wall forming a second trailing edge and two second edges to the wall elements, and - a wall element connects a first guiding device to a second guiding device while forming part of both guiding devices (10, 20), with each wall element having a first edge to one of the first guide walls, a second edge diverging to the first edge in the axial direction to one of the second guide walls and a front-side trailing edge,
A tubular cage having a side wall, the side wall of the cage forming an internal bore to be aligned with an outlet bore of a hollow valve body assembly of a valve and having a ported portion between its end formed with one or more flow ports; wherein the tubular cage is formed such that at least the ported portion includes a tubular outer cage member and a tubular inner cage member, the inner cage member and the outer cage member being formed from a tungsten carbide material, being concentrically aligned, having a length to span at least the ported portion, and being joined together by bonding at an interface formed between the inner cage member and the outer cage member.
A clamping device for machine tools, in particular turning or milling machines provided with a power chuck for fixing a tool or work piece, the clamping jaws of which can be operated by means of the clamping device via an axially adjustable pull and/or pressure rod which is co-rotational during operation of the machine tool, wherein the clamping device comprises: - an axially adjustable pull and/or pressure rod, - an electric motor via which the axial adjustment of the pull and/or pressure rod is performed, wherein the electric motor is arranged to be coaxial to the pull and/or pressure rod but does not co-rotate with the pull and/or pressure rod during operation of the machine tool, - gear means co-rotating with the pull and/or pressure rod, and - a coupling device to couple the electric motor as needed in a torque-fit manner to the gear means and thus to apply an axial force upon the pull and/or pressure rod, wherein the clamping device features a spring force storage unit which sets a sufficient counterforce against an axial displacement of the pull and/or pressure rod against the closing movement of the clamping jaws such as to counterbalance centrifugal forces of the clamping jaws and/or machining forces, characterized in that the spring force storage unit comprises a plurality of spring elements (25, 26) of different design which are mutually effective in parallel, that is a predefined number of spiral springs and a predefined number of gas pressure springs. - an axially adjustable pull and/or pressure rod, - an electric motor via which the axial adjustment of the pull and/or pressure rod is performed, wherein the electric motor is arranged to be coaxial to the pull and/or pressure rod but does not co-rotate with the pull and/or pressure rod during operation of the machine tool, - gear means co-rotating with the pull and/or pressure rod, and - a coupling device to couple the electric motor as needed in a torque-fit manner to the gear means and thus to apply an axial force upon the pull and/or pressure rod,
A therapeutic composition comprising the combination of at least one curcumin component, at least one harmine component, and at least one isovanillin component, wherein the components of the composition are different, said curcumin component selected from the group consisting of curcumin, bisdemethoxy curcumin, (1E,4E)-1,5-bis(3,5-dimethoxyphenyl)-1,4-pentadien-3-one, cardamomnin, 2'-hydroxy-3,4,4',5'-tetramethoxychalcone, 2,2'-dihydroxy-4',6'-dimethoxychalcone, (1E,4E)-1,5-bis(2-hydroxyphenyl)-1,4-pentadien-3-one, demethoxy curcumin, and caffeic acid, said isovanillin component selected from the group consisting of isovanillin, vanillin, orthovanillin, isovanillyl alcohol, isovanillic acid, 5-bromovanillin, 2-bromo-3-hydroxy-4-methoxy benzaldehyde, 2-iodo-3-hydroxy-4-methoxy benzaldehyde, and ethyl vanillin, and said harmine component selected from the group consisting of harmine, harmaline, harmane, harmalol, harmol, and 1,2,3,4-tetrahydroharmane-3-carboxylic acid, wherein the isovanillin component(s) is/are be present at a level of from about 25-85% by weight, the harmine component(s) is/are present at a level of from about 7-50% by weight, and the curcumin component(s) is/are present at a level of from about 5-40% by weight, based upon the total weight of the three components taken as 100% by weight, wherein said composition exhibits anti-cancer therapeutic synergy.
Breeding system for the breeding of crawling insects, preferably insect larvae, comprising: - a drum, comprising at least one wall, defining a drum interior, to house the insects, - a shuffling device, arranged at least partially in the drum interior, to shuffle insects in the drum interior, - a feeding device, to feed nutrients into the drum interior, characterized in that, the system comprises a cooling device having a cooling fluid circuit that is, by means of a flow of coolant in the circuit, configured to withdraw heat from the drum interior. - a drum, comprising at least one wall, defining a drum interior, to house the insects, - a shuffling device, arranged at least partially in the drum interior, to shuffle insects in the drum interior, - a feeding device, to feed nutrients into the drum interior, characterized in that, the system comprises a cooling device having a cooling fluid circuit that is, by means of a flow of coolant in the circuit, configured to withdraw heat from the drum interior.
Method for operating a variable-speed variable displacement pump, in which a conveying mechanism, which is adjustable in a displacement volume per working cycle, is driven by means of a variable-speed drive, which has a peak drive torque (M An.max) and a continuous drive torque (M An,0), comprising: determining a load torque (Δp) at the variable-speed variable displacement pump, depending on an operating state, specifying a setpoint (V Pu,Soll) for a characteristic variable determining the displacement volume per working cycle to an adjustment device of the conveying mechanism such that a drive torque of the variable-speed drive corresponds either to more than the continuous drive torque (M an,0) and to not more than the peak drive torque (M an,max) of the drive, or to not more than the continuous drive torque (M an,0) of the drive, wherein a first actuating variable (α S,Spitze) is determined from the load torque (Δp) and the peak drive torque (M An,max) of the drive according to a first filter function with a time delay (T P,Spitze) and a second actuating variable (α S,Dauer) is determined from the load torque (Δp) and the continuous drive torque (M An,0) of the drive according to a second filter function with a time delay (T P,Dauer), wherein the setpoint (V Pu,Soll) for the characteristic variable determining the displacement volume per working cycle is specified by means of the smaller of the first and second actuating variable. determining a load torque (Δp) at the variable-speed variable displacement pump, depending on an operating state, specifying a setpoint (V Pu,Soll) for a characteristic variable determining the displacement volume per working cycle to an adjustment device of the conveying mechanism such that a drive torque of the variable-speed drive corresponds either to more than the continuous drive torque (M an,0) and to not more than the peak drive torque (M an,max) of the drive, or to not more than the continuous drive torque (M an,0) of the drive, wherein a first actuating variable (α S,Spitze) is determined from the load torque (Δp) and the peak drive torque (M An,max) of the drive according to a first filter function with a time delay (T P,Spitze) and a second actuating variable (α S,Dauer) is determined from the load torque (Δp) and the continuous drive torque (M An,0) of the drive according to a second filter function with a time delay (T P,Dauer), wherein the setpoint (V Pu,Soll) for the characteristic variable determining the displacement volume per working cycle is specified by means of the smaller of the first and second actuating variable.
Rodent trap for catching and killing rodents, in particular mice and/or rats, comprising clamp means at least having an upper jaw part and a lower jaw part, wherein the upper jaw part is able to swing relative to the lower jaw part from an open position to a closed position, in which it hits and kills a rodent, the upper jaw part being at least partially rotatable around a jaw rotational axis (A jaw) a lifting lever for releasing the clamp means from the open position, the lifting lever being activatable by a rodent on a first side (f) of the jaw rotational axis (A jaw), a force means, in particular at least one spring, enabling the clamp means to change from the open position into the closed position when released, the lifting lever comprising a latch means on a latch side of the lifting lever being arranged on a second side of the jaw rotational axis (A jaw), opposite of the first side of the jaw rotational axis (A jaw), characterized in that the force means in the closed position exerts a closing force on the upper jaw part and the lower jaw part such that both jaws (3,4) are pressed against each other, wherein a longitudinal centerline of the force means is located beside the jaw rotational axis (A jaw), preferably located on the first side of the jaw rotational axis (A jaw). clamp means at least having an upper jaw part and a lower jaw part, wherein the upper jaw part is able to swing relative to the lower jaw part from an open position to a closed position, in which it hits and kills a rodent, the upper jaw part being at least partially rotatable around a jaw rotational axis (A jaw) a lifting lever for releasing the clamp means from the open position, the lifting lever being activatable by a rodent on a first side (f) of the jaw rotational axis (A jaw), a force means, in particular at least one spring, enabling the clamp means to change from the open position into the closed position when released, the lifting lever comprising a latch means on a latch side of the lifting lever being arranged on a second side of the jaw rotational axis (A jaw), opposite of the first side of the jaw rotational axis (A jaw), characterized in that the force means in the closed position exerts a closing force on the upper jaw part and the lower jaw part such that both jaws (3,4) are pressed against each other, wherein a longitudinal centerline of the force means is located beside the jaw rotational axis (A jaw), preferably located on the first side of the jaw rotational axis (A jaw).
A riding mower comprising: a mower assembly supported on a vehicle body frame between pairs of left and right rear wheels and front wheels; a steering assembly configured for operation by a driver; a driver seat supported on the vehicle body frame; and a floor panel provided on the vehicle body frame extending frontward from an area including the driver seat; the floor panel comprising: a main panel located in front of the driver seat; and a left footrest and a right footrest each extending further frontward from the main panel; and a recessed portion being formed on at least one side edge of the floor panel, the recessed portion including a side edge dropoff point that, in a plan view, is the shortest distance to a front-back direction centerline of the vehicle body; and the recessed portion being formed from a front recessed side edge that extends forward from the side edge dropoff point, and a rear recessed side edge that extends rearward from the side edge dropoff point. a mower assembly supported on a vehicle body frame between pairs of left and right rear wheels and front wheels; a steering assembly configured for operation by a driver; a driver seat supported on the vehicle body frame; and a floor panel provided on the vehicle body frame extending frontward from an area including the driver seat; the floor panel comprising: a main panel located in front of the driver seat; and a left footrest and a right footrest each extending further frontward from the main panel; and a main panel located in front of the driver seat; and a left footrest and a right footrest each extending further frontward from the main panel; and a recessed portion being formed on at least one side edge of the floor panel, the recessed portion including a side edge dropoff point that, in a plan view, is the shortest distance to a front-back direction centerline of the vehicle body; and the recessed portion being formed from a front recessed side edge that extends forward from the side edge dropoff point, and a rear recessed side edge that extends rearward from the side edge dropoff point.
A method for controlling the antibody-dependent cellular cytotoxicity (ADCC) of an IgG antibody molecule, said method comprising regulating the presence or absence of binding of fucose to the N -acetylglucosamine of the reducing terminus of a biantennary complex type N-glycoside-linked sugar chain by deleting a gene encoding an α1,6-fucosyltransferase in a host cell, non-human animal or plant, or by adding a mutation to the gene to reduce or eliminate the enzyme activity in a host cell, non-human animal or plant, wherein said sugar chain binds to said antibody and mainly has the following structure: wherein said regulating comprises binding a sugar chain in which fucose is not bound to the N-acetylglucosamine of the reducing terminus of a complex type N-glycoside-linked sugar chain to the antibody molecule, to thereby promote ADCC of the antibody molecule.
A method for diagnosing a postoperative pulmonary infection in a patient who underwent surgery, comprising a step of measuring the concentration of endocan in a blood sample obtained from said patient, at a time point comprised between 3h and 30h after surgery.
A surgical drilling device comprising: a housing defining a first arcuate channel, a second elongate channel, and a third elongate channel positioned adjacent said second channel; a retractable guide tube assembly comprising an arcuate guide tube slidingly positioned in the first arcuate channel of the housing, the arcuate guide tube operatively connected to an actuating rod slidingly positioned in the second channel of the housing wherein the actuating rod is configured to controllably advance the arcuate guide tube from the housing and retract the arcuate guide tube into the housing; and a flexible cable drill having a first distal portion slidingly positioned in the arcuate guide tube and a second proximal portion slidingly positioned in the third channel of the housing. a housing defining a first arcuate channel, a second elongate channel, and a third elongate channel positioned adjacent said second channel; a retractable guide tube assembly comprising an arcuate guide tube slidingly positioned in the first arcuate channel of the housing, the arcuate guide tube operatively connected to an actuating rod slidingly positioned in the second channel of the housing wherein the actuating rod is configured to controllably advance the arcuate guide tube from the housing and retract the arcuate guide tube into the housing; and a flexible cable drill having a first distal portion slidingly positioned in the arcuate guide tube and a second proximal portion slidingly positioned in the third channel of the housing.
A method for playing a video, comprising: obtaining video information of each of moving objects contained in a currently played video frame image, wherein the video information of each of the moving objects comprises at least: a position of this moving object in the video frame image and a size of this moving object; updating a pre-created moving object pool based on the obtained video information of each of the moving objects; extracting, from the moving object pool, a size of a forefront moving object in the moving object pool and a position of the forefront moving object in the video frame image, obtaining a first sub-image containing the forefront moving object from the video frame image based on the position of the forefront moving object in the video frame image and the size of the forefront moving object, and displaying the first sub-image in a first window; and sequentially obtaining second sub-images surrounding the forefront moving object from a cruising region of the video frame image, based on the position of the forefront moving object in the video frame image, the size of the forefront moving object, a preset cruising speed and a preset cruising region size, and displaying the second sub-images in a second window sequentially. obtaining video information of each of moving objects contained in a currently played video frame image, wherein the video information of each of the moving objects comprises at least: a position of this moving object in the video frame image and a size of this moving object; updating a pre-created moving object pool based on the obtained video information of each of the moving objects; extracting, from the moving object pool, a size of a forefront moving object in the moving object pool and a position of the forefront moving object in the video frame image, obtaining a first sub-image containing the forefront moving object from the video frame image based on the position of the forefront moving object in the video frame image and the size of the forefront moving object, and displaying the first sub-image in a first window; and sequentially obtaining second sub-images surrounding the forefront moving object from a cruising region of the video frame image, based on the position of the forefront moving object in the video frame image, the size of the forefront moving object, a preset cruising speed and a preset cruising region size, and displaying the second sub-images in a second window sequentially.
A method to measure and/or monitor consciousness in a subject, comprising the steps: a) Acquisition of brain activity signals; b) Pre-processing of the brain activity signals of step a); c) Using Permutation Entropy to transform the signals from step b) into a series of discrete symbols; characterized by: d) Analysis of the series of symbols from step c) with weighted symbolic mutual information (wSMI), using the formula: wSMI = ∑ x ∈ X ∑ y ∈ Y w x y p x y log p x y p x p y where x and y are all symbols present in signals from electrodes X and Y respectively; p(x,y) is the joint probability of co-occurrence of symbol x in electrode X and symbol y in electrode Y; and p(x) and p(y) are the probabilities of those symbols in each respective signal and w(x,y) is a weight matrix. e) Calculation of a consciousness index based upon the outcome of the analysis of step d). a) Acquisition of brain activity signals; b) Pre-processing of the brain activity signals of step a); c) Using Permutation Entropy to transform the signals from step b) into a series of discrete symbols; characterized by: d) Analysis of the series of symbols from step c) with weighted symbolic mutual information (wSMI), using the formula: wSMI = ∑ x ∈ X ∑ y ∈ Y w x y p x y log p x y p x p y where x and y are all symbols present in signals from electrodes X and Y respectively; p(x,y) is the joint probability of co-occurrence of symbol x in electrode X and symbol y in electrode Y; and p(x) and p(y) are the probabilities of those symbols in each respective signal and w(x,y) is a weight matrix. e) Calculation of a consciousness index based upon the outcome of the analysis of step d).