A device for implanting biological units into tissue, comprising: a robotic system having a robotic arm and one or more control mechanisms; an implanting tool having a lumen therethrough, the implanting tool being connected to and manipulated by the robotic arm; and a cartridge having a plurality of receptacles each sized and configured to retain a biological unit, wherein the one or more control mechanisms is configured to automatically align a selected cartridge receptacle with the lumen of the implanting tool and urge the biological unit from the selected receptacle through the lumen of the implanting tool into the tissue; wherein the cartridge is a rectilinear cartridge; wherein the one or more control mechanisms includes a cartridge shuttle subsystem; wherein the cartridge shuttle subsystem comprises a base member having a longitudinal channel extending entirely through the base member in a longitudinal direction and a transverse channel perpendicular to the longitudinal channel and extending entirely across the base member in a transverse direction; wherein the rectilinear cartridge slides transversely within the transverse channel of the cartridge shuttle subsystem to align the selected cartridge receptacle with the lumen of the implanting tool; and wherein the device further comprises an obturator positioned within the longitudinal channel to pass through the selected cartridge receptacle, and wherein the control mechanism directs passage of the obturator through the selected cartridge receptacle to urge the biological unit from the selected cartridge receptacle, and wherein at least one of the plurality of receptacles comprises a pressure relief structure that limits the maximum suction created within the receptacle from a source of suction, and preferably wherein the pressure relief structure comprises one or more notches. a robotic system having a robotic arm and one or more control mechanisms; an implanting tool having a lumen therethrough, the implanting tool being connected to and manipulated by the robotic arm; and a cartridge having a plurality of receptacles each sized and configured to retain a biological unit, wherein the one or more control mechanisms is configured to automatically align a selected cartridge receptacle with the lumen of the implanting tool and urge the biological unit from the selected receptacle through the lumen of the implanting tool into the tissue; wherein the cartridge is a rectilinear cartridge; wherein the one or more control mechanisms includes a cartridge shuttle subsystem; wherein the cartridge shuttle subsystem comprises a base member having a longitudinal channel extending entirely through the base member in a longitudinal direction and a transverse channel perpendicular to the longitudinal channel and extending entirely across the base member in a transverse direction; wherein the rectilinear cartridge slides transversely within the transverse channel of the cartridge shuttle subsystem to align the selected cartridge receptacle with the lumen of the implanting tool; and wherein the device further comprises an obturator positioned within the longitudinal channel to pass through the selected cartridge receptacle, and wherein the control mechanism directs passage of the obturator through the selected cartridge receptacle to urge the biological unit from the selected cartridge receptacle, and wherein at least one of the plurality of receptacles comprises a pressure relief structure that limits the maximum suction created within the receptacle from a source of suction, and preferably wherein the pressure relief structure comprises one or more notches.