A nebulizer device (1, 10, 20, 30, 40, 50, 80, 90), such as a spray can, for the topical application of a liquid cooling medium, comprising: - a container (2, 11, 21, 33, 41, 56, 91) comprising a propellant gas (57, 92) and a liquid cooling medium (58, 93), which liquid cooling medium cools the skin by evaporation to a temperature below the freezing point when applied to the skin; - an actuatable valve (12, 54, 94) attached to the container; and - a nozzle (3, 13, 24, 34, 42, 55, 99) attached to the valve, designed for generating a stream or spray, - a spacer, - a cover means with an opening, wherein the valve: - comprises a mixing chamber (53, 96) attached to the nozzle; and - comprises a first (51, 97) and a second inlet (52, 98) attached to the mixing chamber for the separate delivery of the liquid cooling medium and the propellant gas to the mixing chamber, wherein the mixing chamber is provided with a Venturi (59, 95) and is designed for forming a colloidal mixture comprising the liquid colling medium and the propellant gas before delivering the colloidal mixture to the nozzle, wherein the device is configured such that when the nozzle is pointed downwards at a lower level than the container: - the first inlet delivers the propellant gas to the mixing chamber and the second inlet delivers the liquid cooling medium to the mixing chamber; - upon activating the nebulizer, propellant gas is delivered to the mixing chamber via the first inlet to which the liquid cooling medium is drawn up by the Venturi effect via second inlet; - the colloidal mixture comprises a dispersed phase consisting of the liquid cooling medium and a continuous phase consisting of the propellant gas; and wherein the nebulizer is connected to the spacer, which spacer is connected to the cover means provided with the opening, wherein the center axis of the stream or spray to be generated by the nebulizer extends through the opening. - a container (2, 11, 21, 33, 41, 56, 91) comprising a propellant gas (57, 92) and a liquid cooling medium (58, 93), which liquid cooling medium cools the skin by evaporation to a temperature below the freezing point when applied to the skin; - an actuatable valve (12, 54, 94) attached to the container; and - a nozzle (3, 13, 24, 34, 42, 55, 99) attached to the valve, designed for generating a stream or spray, - a spacer, - a cover means with an opening, wherein the valve: - comprises a mixing chamber (53, 96) attached to the nozzle; and - comprises a first (51, 97) and a second inlet (52, 98) attached to the mixing chamber for the separate delivery of the liquid cooling medium and the propellant gas to the mixing chamber, - comprises a mixing chamber (53, 96) attached to the nozzle; and - comprises a first (51, 97) and a second inlet (52, 98) attached to the mixing chamber for the separate delivery of the liquid cooling medium and the propellant gas to the mixing chamber, wherein the mixing chamber is provided with a Venturi (59, 95) and is designed for forming a colloidal mixture comprising the liquid colling medium and the propellant gas before delivering the colloidal mixture to the nozzle, wherein the device is configured such that when the nozzle is pointed downwards at a lower level than the container: - the first inlet delivers the propellant gas to the mixing chamber and the second inlet delivers the liquid cooling medium to the mixing chamber; - upon activating the nebulizer, propellant gas is delivered to the mixing chamber via the first inlet to which the liquid cooling medium is drawn up by the Venturi effect via second inlet; - the colloidal mixture comprises a dispersed phase consisting of the liquid cooling medium and a continuous phase consisting of the propellant gas; and - the first inlet delivers the propellant gas to the mixing chamber and the second inlet delivers the liquid cooling medium to the mixing chamber; - upon activating the nebulizer, propellant gas is delivered to the mixing chamber via the first inlet to which the liquid cooling medium is drawn up by the Venturi effect via second inlet; - the colloidal mixture comprises a dispersed phase consisting of the liquid cooling medium and a continuous phase consisting of the propellant gas; and wherein the nebulizer is connected to the spacer, which spacer is connected to the cover means provided with the opening, wherein the center axis of the stream or spray to be generated by the nebulizer extends through the opening.