An isolated antibody, or a functional fragment thereof, which on tumors i) specifically binds to the ligand independent activated form of cMet ii) does not bind to the non activated form of cMet and iii) does not bind to the ligand dependent activated form of cMet, characterized in that: i) it does not block the binding of the ligand HGF to cMet; ii) it interacts with the extra-cellular region of cMet between amino acid residues 1 and 950; and iii) it is selected from the group consisting of: a) an antibody, or a functional fragment thereof, comprising: - a light chain comprising the following three CDRs as defined according to IMGT, respectively CDR-L1 having the sequence SEQ ID No. 1, CDR-L2 having the sequence SEQ ID No. 2 and CDR-L3 having the sequence SEQ ID No.3; and - a heavy chain comprising the following three CDRs as defined according to IMGT, respectively CDR-H1 having the sequence SEQ ID No. 4, CDR-H2 having the sequence SEQ ID No. 5 and CDR-H3 having the sequence SEQ ID No. 6, and b) an antibody, or a functional fragment thereof, comprising - a light chain comprising the following three CDRs as defined according to IMGT, respectively CDR-L1 having the sequence SEQ ID No. 9, CDR-L2 having the sequence SEQ ID No. 10 and CDR-L3 having the sequence SEQ ID No.11; and - a heavy chain comprising the following three CDRs as defined according to IMGT, respectively CDR-H1 having the sequence SEQ ID No. 12, CDR-H2 having the sequence SEQ ID No. 13 and CDR-H3 having the sequence SEQ ID No. 14. i) it does not block the binding of the ligand HGF to cMet; ii) it interacts with the extra-cellular region of cMet between amino acid residues 1 and 950; and iii) it is selected from the group consisting of: a) an antibody, or a functional fragment thereof, comprising: - a light chain comprising the following three CDRs as defined according to IMGT, respectively CDR-L1 having the sequence SEQ ID No. 1, CDR-L2 having the sequence SEQ ID No. 2 and CDR-L3 having the sequence SEQ ID No.3; and - a heavy chain comprising the following three CDRs as defined according to IMGT, respectively CDR-H1 having the sequence SEQ ID No. 4, CDR-H2 having the sequence SEQ ID No. 5 and CDR-H3 having the sequence SEQ ID No. 6, and b) an antibody, or a functional fragment thereof, comprising - a light chain comprising the following three CDRs as defined according to IMGT, respectively CDR-L1 having the sequence SEQ ID No. 9, CDR-L2 having the sequence SEQ ID No. 10 and CDR-L3 having the sequence SEQ ID No.11; and - a heavy chain comprising the following three CDRs as defined according to IMGT, respectively CDR-H1 having the sequence SEQ ID No. 12, CDR-H2 having the sequence SEQ ID No. 13 and CDR-H3 having the sequence SEQ ID No. 14. a) an antibody, or a functional fragment thereof, comprising: - a light chain comprising the following three CDRs as defined according to IMGT, respectively CDR-L1 having the sequence SEQ ID No. 1, CDR-L2 having the sequence SEQ ID No. 2 and CDR-L3 having the sequence SEQ ID No.3; and - a heavy chain comprising the following three CDRs as defined according to IMGT, respectively CDR-H1 having the sequence SEQ ID No. 4, CDR-H2 having the sequence SEQ ID No. 5 and CDR-H3 having the sequence SEQ ID No. 6, and - a light chain comprising the following three CDRs as defined according to IMGT, respectively CDR-L1 having the sequence SEQ ID No. 1, CDR-L2 having the sequence SEQ ID No. 2 and CDR-L3 having the sequence SEQ ID No.3; and - a heavy chain comprising the following three CDRs as defined according to IMGT, respectively CDR-H1 having the sequence SEQ ID No. 4, CDR-H2 having the sequence SEQ ID No. 5 and CDR-H3 having the sequence SEQ ID No. 6, and b) an antibody, or a functional fragment thereof, comprising - a light chain comprising the following three CDRs as defined according to IMGT, respectively CDR-L1 having the sequence SEQ ID No. 9, CDR-L2 having the sequence SEQ ID No. 10 and CDR-L3 having the sequence SEQ ID No.11; and - a heavy chain comprising the following three CDRs as defined according to IMGT, respectively CDR-H1 having the sequence SEQ ID No. 12, CDR-H2 having the sequence SEQ ID No. 13 and CDR-H3 having the sequence SEQ ID No. 14. - a light chain comprising the following three CDRs as defined according to IMGT, respectively CDR-L1 having the sequence SEQ ID No. 9, CDR-L2 having the sequence SEQ ID No. 10 and CDR-L3 having the sequence SEQ ID No.11; and - a heavy chain comprising the following three CDRs as defined according to IMGT, respectively CDR-H1 having the sequence SEQ ID No. 12, CDR-H2 having the sequence SEQ ID No. 13 and CDR-H3 having the sequence SEQ ID No. 14.