mhurhangee/ep-ind-claims huggingface dataset:
A method for identifying the likelihood that a mammalian subject will exhibit an adverse reaction to telomerase inhibition therapy comprising, (a) determining the average or median telomere length in a biological sample comprising cells obtained from the mammalian subject prior to or at the time of treatment with a telomerase inhibition therapy and multiplying the average or median telomere length by a coefficient to arrive at a telomere length component; (b) multiplying the intended treatment dosage by a coefficient to arrive at a dosage component; and (c) producing the sum of the telomere component, the dosage component and a constant; and (d) determining the expected likelihood of an adverse reaction in the mammalian subject from treatment with the telomerase inhibition therapy. (a) determining the average or median telomere length in a biological sample comprising cells obtained from the mammalian subject prior to or at the time of treatment with a telomerase inhibition therapy and multiplying the average or median telomere length by a coefficient to arrive at a telomere length component; (b) multiplying the intended treatment dosage by a coefficient to arrive at a dosage component; and (c) producing the sum of the telomere component, the dosage component and a constant; and (d) determining the expected likelihood of an adverse reaction in the mammalian subject from treatment with the telomerase inhibition therapy.
Lifetime measuring device for a blade of a lawnmower, said device comprising at least one first sensor configured to detect the impacts of the blade with stones or other objects, at least one second sensor configured to detect the lawnmower motor rotation revolutions and a control unit comprising first means (31, 32) configured to measure the intensity of the single impacts of the blade of the lawnmower in response to the detected data of the first sensor and configured to measure the rotation speed of the blade in response to the detected data of the second sensor, said control unit comprising second means configured to count the blade working hours, said control unit being configured to process the lifetime of the blade as a function of the carried out measures and of said counted working hours of the blade.
A method for removing a coating from an airfoil portion of a turbine engine component characterised by comprising the steps of: placing a maskant (10; 30) formed from an electrically conductive material on opposed sides of an edge of said airfoil portion; immersing said turbine engine component with said maskant into a bath; and electrochemically stripping a coating from unmasked portions of said turbine engine component. placing a maskant (10; 30) formed from an electrically conductive material on opposed sides of an edge of said airfoil portion; immersing said turbine engine component with said maskant into a bath; and electrochemically stripping a coating from unmasked portions of said turbine engine component.
A polymerizable composition comprising: a binder polymer being a polymer having a repeating unit represented by the following formula wherein R 1 represents a hydrogen atom or a methyl group; R 2 represents a linking group containing at least two of a carbon atom, a hydrogen atom, an oxygen atom, a nitrogen atom and a sulfur atom and carrying 2 to 82 atoms; A represents an oxygen atom or -NR 3 - wherein R 3 represents a hydrogen atom or a monovalent hydrocarbon group having 1 to 10 carbon atoms; and n represents an integer of from 1 to 5; a compound having a polymerizable unsaturated group; and a compound which has a triarylsulfonium salt structure and in which a sum of Hammett's constants of all substituents bonded to the aryl skeleton is larger than 0.46. a binder polymer being a polymer having a repeating unit represented by the following formula wherein R 1 represents a hydrogen atom or a methyl group; R 2 represents a linking group containing at least two of a carbon atom, a hydrogen atom, an oxygen atom, a nitrogen atom and a sulfur atom and carrying 2 to 82 atoms; A represents an oxygen atom or -NR 3 - wherein R 3 represents a hydrogen atom or a monovalent hydrocarbon group having 1 to 10 carbon atoms; and n represents an integer of from 1 to 5; a compound having a polymerizable unsaturated group; and a compound which has a triarylsulfonium salt structure and in which a sum of Hammett's constants of all substituents bonded to the aryl skeleton is larger than 0.46.
A method of making an ophthalmic device comprising: forming a mask configured to transmit substantially all visible light along an optical axis of the eye, characterized in that the mask further comprises a transition portion configured to switch between at least a first degree of less opacity and a second degree of enhanced opacity in response to exposure to an external stimulus; wherein the transition portion comprises a photochromic chromophore within a polymer matrix, the polymer matrix having a glass transition temperature (T g) and the transition portion being configured to remain locked into the second degree of enhanced opacity after removal of the external stimulus until the polymer matrix is heated to undergo a glass transition, the transition portion then returning to the first degree of less opacity. forming a mask configured to transmit substantially all visible light along an optical axis of the eye, characterized in that the mask further comprises a transition portion configured to switch between at least a first degree of less opacity and a second degree of enhanced opacity in response to exposure to an external stimulus; wherein the transition portion comprises a photochromic chromophore within a polymer matrix, the polymer matrix having a glass transition temperature (T g) and the transition portion being configured to remain locked into the second degree of enhanced opacity after removal of the external stimulus until the polymer matrix is heated to undergo a glass transition, the transition portion then returning to the first degree of less opacity.
Structure for the production of stab-resistant ballistic protection, comprising at least one textile element including fibers having a negative axial Coefficient of Thermal Expansion, the textile element being impregnated with at least one polymer resin having a positive Coefficient of Thermal Expansion, hardness greater than 75 Shore D and a cohesive strength such that, once dry, the polymer resin becomes crumbly.
Method for producing preforms, by layup of fibres on a layup surface, comprising - the application of a binder on at least one continuous flat dry fibre, comprising two opposite main faces (91a, 91b), and - the layup of said fibre provided with binder by means of a layup head in order to form a preform, characterised in that the application of binder on a fibre is carried out by means of at least one fiberising nozzle comprising a discharge orifice supplied with liquid or pasty binder, and one or several injection orifices supplied with pressurized gas, in such a way that said nozzle is able to deliver the binder in the form of a spiral filament, the spirals of filament being deposited on a first main face of the fibre running underneath the nozzle in order to obtain a fibre provided with filaments (93, 94) of binder. - the application of a binder on at least one continuous flat dry fibre, comprising two opposite main faces (91a, 91b), and - the layup of said fibre provided with binder by means of a layup head in order to form a preform,
A compound of Formula I, or a pharmaceutically acceptable salt thereof: wherein: G 1 is C 6 -C 8 alkyl optionally substituted with 1-3 fluorines; or G 1 is one of the following: Z 1 is -C 1 -C 2 alkylene; Z 2 is -O-, -S(O 2)-, or -CH 2 -; Z 3 is -C 1 -C 2 alkylene; G 2 and G 3 are independently selected from H and -CH 3; G 4 is phenyl, pyridine, pyrimidine or pyrazine; G 5 is G 4, -OG 4, -O(C 1 -C 2 alkyl optionally substituted with 1-3 fluorines), or G 5 is one of the following: R 1 is hydrogen, C 1 -C 3 alkyl optionally substituted with 1-3 fluorines, or cyclopropyl optionally substituted with 1-2 fluorines; R 2 is C 1 -C 2 alkyl optionally substituted with 1-3 fluorines, or C 3 -C 4 cycloalkyl optionally substituted with 1-2 fluorines; R 3 is hydrogen, Cl, F, CH 3, or OCH 3; W is selected from: X 1, X 2 and X 3 are independently selected from H, F, and Cl, or one of the group X 1, X 2 and X 3 is selected from -CN, -OCH 3, -CH 3, -CH 2 F, -CHF 2, and -CF 3. G 1 is C 6 -C 8 alkyl optionally substituted with 1-3 fluorines; or G 1 is one of the following: Z 1 is -C 1 -C 2 alkylene; Z 2 is -O-, -S(O 2)-, or -CH 2 -; Z 3 is -C 1 -C 2 alkylene; G 2 and G 3 are independently selected from H and -CH 3; G 4 is phenyl, pyridine, pyrimidine or pyrazine; G 5 is G 4, -OG 4, -O(C 1 -C 2 alkyl optionally substituted with 1-3 fluorines), or G 5 is one of the following: R 1 is hydrogen, C 1 -C 3 alkyl optionally substituted with 1-3 fluorines, or cyclopropyl optionally substituted with 1-2 fluorines; R 2 is C 1 -C 2 alkyl optionally substituted with 1-3 fluorines, or C 3 -C 4 cycloalkyl optionally substituted with 1-2 fluorines; R 3 is hydrogen, Cl, F, CH 3, or OCH 3; W is selected from: X 1, X 2 and X 3 are independently selected from H, F, and Cl, or one of the group X 1, X 2 and X 3 is selected from -CN, -OCH 3, -CH 3, -CH 2 F, -CHF 2, and -CF 3.
A method of monitoring a milking process, the milking process performed by a milking apparatus including at least one teatcup (2, 3, 4, 5) configured to receive a teat of a milking animal and at least one airline configured to deliver varying levels of pressure to the teatcup, the method including the steps of: - measuring airflow within the airline using a flow sensor to obtain an indication of volume of displaced air within the teatcup; - comparing the indication of volume with a reference value; and - determining a connection parameter relating to an extent of connection between the teat and the teatcup based on the comparison, characterized in that the method includes adjusting a position of the teatcup relative to the teat on the basis of the connection parameter. - measuring airflow within the airline using a flow sensor to obtain an indication of volume of displaced air within the teatcup; - comparing the indication of volume with a reference value; and - determining a connection parameter relating to an extent of connection between the teat and the teatcup based on the comparison, characterized in that the method includes adjusting a position of the teatcup relative to the teat on the basis of the connection parameter. - determining a connection parameter relating to an extent of connection between the teat and the teatcup based on the comparison, characterized in that the method includes adjusting a position of the teatcup relative to the teat on the basis of the connection parameter.
A battery pack, comprising: a box body assembly, comprising a box body and a plurality of fixing beams which are fixed to the box body and divide the box body into several containing cavities; a plurality of battery modules, each of which comprises a plurality of battery cells and is correspondingly arranged in each containing cavity; and a plurality of restraint components, each of which comprises a limit part, a first mounting part and a second mounting part, wherein each limit part covers each battery module correspondingly, the first mounting part and the second mounting part are respectively connected on both sides of the limit part in the direction in which the plurality of fixing beams are arranged, and are fixed with the fixing beams on both sides of the corresponding battery module respectively; wherein, for two adjacent restraint components, the first mounting part of one restraint component and the second mounting part of the other restraint component are fixed on the same fixing beam and are overlapped in a height direction. a box body assembly, comprising a box body and a plurality of fixing beams which are fixed to the box body and divide the box body into several containing cavities; a plurality of battery modules, each of which comprises a plurality of battery cells and is correspondingly arranged in each containing cavity; and a plurality of restraint components, each of which comprises a limit part, a first mounting part and a second mounting part, wherein each limit part covers each battery module correspondingly, the first mounting part and the second mounting part are respectively connected on both sides of the limit part in the direction in which the plurality of fixing beams are arranged, and are fixed with the fixing beams on both sides of the corresponding battery module respectively; wherein, for two adjacent restraint components, the first mounting part of one restraint component and the second mounting part of the other restraint component are fixed on the same fixing beam and are overlapped in a height direction.
Magnetic floating device comprising: - a base unit with a shell, a magnetic floating controller and at least one base magnet; and - a floating unit with a covering component, a functional component and at least one floating magnet, wherein the magnetic floating controller is designed to adjust the floating unit between a floating state and a grounded state by means of an adjustment in magnetism of the at least one base magnet, wherein in the floating state, the floating unit is floating above the base unit and in the grounded state, the floating unit is docked in the shell of the base unit, characterized in that - the magnetic floating device comprises a signal input unit which is designed to receive an announcement signal that signals an anticipation of a jerk event; and - the magnetic floating controller is designed to adjust the floating unit from the floating state to the grounded state in order to temporarily dock and/or lock the floating unit in the shell of the base unit by adjusting the magnetism of the at least one base magnet as a function of the announcement signal received by the signal input unit. - a base unit with a shell, a magnetic floating controller and at least one base magnet; and - a floating unit with a covering component, a functional component and at least one floating magnet, wherein the magnetic floating controller is designed to adjust the floating unit between a floating state and a grounded state by means of an adjustment in magnetism of the at least one base magnet, wherein in the floating state, the floating unit is floating above the base unit and in the grounded state, the floating unit is docked in the shell of the base unit, - the magnetic floating device comprises a signal input unit which is designed to receive an announcement signal that signals an anticipation of a jerk event; and - the magnetic floating controller is designed to adjust the floating unit from the floating state to the grounded state in order to temporarily dock and/or lock the floating unit in the shell of the base unit by adjusting the magnetism of the at least one base magnet as a function of the announcement signal received by the signal input unit.
A vehicle and compressor assembly comprising: a vehicle; a compressor mounted to the vehicle, the compressor having an intake port and an exhaust port; and a silencer having an inlet port in communication with the air exhaust port of the compressor, the silencer including a silencer housing and a resonator assembly removably positioned inside the silencer housing, the silencer housing including a removable portion that facilitates access to and removal of the resonator assembly; wherein the silencer housing includes an inner surface and a groove in the inner surface, the resonator assembly being at least partially positioned in the groove; and wherein the resonator assembly includes a resonator plate and a plurality of resonator pipes extending through the plate, the resonator plate being slidably positioned at least partially in the groove. a vehicle; a compressor mounted to the vehicle, the compressor having an intake port and an exhaust port; and a silencer having an inlet port in communication with the air exhaust port of the compressor, the silencer including a silencer housing and a resonator assembly removably positioned inside the silencer housing, the silencer housing including a removable portion that facilitates access to and removal of the resonator assembly; wherein the silencer housing includes an inner surface and a groove in the inner surface, the resonator assembly being at least partially positioned in the groove; and wherein the resonator assembly includes a resonator plate and a plurality of resonator pipes extending through the plate, the resonator plate being slidably positioned at least partially in the groove.
Cooking container comprising a bowl that comprises a base, a side wall and an energy recovery device intended to engage with an induction heating means, said energy recovery device comprising a rigid holder that is separate from the bowl, in the shape of a loop arranged on the base and at least one electrically insulated conductive element and attached by means of deposition to the support, in particular by means of screen printing, pad printing, thermal spraying, decalcomania or laser sintering, characterised in that the support comprises an open loop that comprises two free ends (17a, 17b) and two extensions (15, 16) that extend radially without touching one another starting at the two free ends (17a, 17b), from the base towards the side wall and in that the conductive element is attached by deposition to the open loop and to the two extensions (15, 16).
An apparatus for manufacturing molten iron, comprising: an iron ore-mixing/pre-reducing furnace that receives and mixes natural iron ore and oxidized iron ore supplied from an iron ore oxidizing-burning furnace, and heats or pre-reduces iron ore using a flue gas supplied from an iron ore reduction furnace; the iron ore reduction furnace that receives pre-processed iron ore discharged from the iron ore-mixing/pre-reducing furnace via an iron ore supply line or partially reduced iron ore, and reduces the iron ore using a reduction gas discharged from a molten gasification furnace; the molten gasification furnace that receives coal and some of reduced iron produced by the iron ore reduction furnace via a first reduced iron supply line and produces molten iron and a reduction gas to be supplied to the iron ore reduction furnace; and the iron ore oxidizing-burning furnace that receives new iron ore and some of reduced iron discharged from the iron ore reduction furnace via a second reduced iron supply line and changes the new iron ore into oxidized iron ore including a larger amount of oxygen by burning the new iron ore and the some reduced iron with air. an iron ore-mixing/pre-reducing furnace that receives and mixes natural iron ore and oxidized iron ore supplied from an iron ore oxidizing-burning furnace, and heats or pre-reduces iron ore using a flue gas supplied from an iron ore reduction furnace; the iron ore reduction furnace that receives pre-processed iron ore discharged from the iron ore-mixing/pre-reducing furnace via an iron ore supply line or partially reduced iron ore, and reduces the iron ore using a reduction gas discharged from a molten gasification furnace; the molten gasification furnace that receives coal and some of reduced iron produced by the iron ore reduction furnace via a first reduced iron supply line and produces molten iron and a reduction gas to be supplied to the iron ore reduction furnace; and the iron ore oxidizing-burning furnace that receives new iron ore and some of reduced iron discharged from the iron ore reduction furnace via a second reduced iron supply line and changes the new iron ore into oxidized iron ore including a larger amount of oxygen by burning the new iron ore and the some reduced iron with air.
A method for achieving a desired level of curl in hair during a relaxation process comprising: (a) applying to the hair one or more relaxing agents comprising an alkali metal containing hydroxide; and (b) applying to the hair an active agent of Formula II: wherein Z is a linker or is absent and wherein the linker is not a polymer; m and n are each an integer independently selected from 1-6, and the sum of m+n is equal to or greater than 2; B is a functional group capable of forming a covalent bond with a nucleophile and B is independently selected from the group consisting of: wherein R is independently selected from the group consisting of hydrogen, C 1-6 alkyl groups, aryl groups, or an ionizable functional groups and Z' is oxygen, NH or is absent, and G is carbon and g is 1, or G is sulfur and g is 2; A is an ionizable functional group independently selected from the group consisting of: -COOH, -SO 3 H, -PO 3 H 2, -N(R 1) 2, -N(R 1) 3; wherein R 1 is independently selected from the group consisting of a hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocycloalkyl and heteroaryl groups; wherein each R 1 is independently unsubstituted or substituted with one or more substituents;wherein the one or more relaxing agents cause relaxation of the hair; and wherein steps (a) and (b) are performed simultaneously. (a) applying to the hair one or more relaxing agents comprising an alkali metal containing hydroxide; and (b) applying to the hair an active agent of Formula II: wherein Z is a linker or is absent and wherein the linker is not a polymer; m and n are each an integer independently selected from 1-6, and the sum of m+n is equal to or greater than 2; B is a functional group capable of forming a covalent bond with a nucleophile and B is independently selected from the group consisting of: wherein R is independently selected from the group consisting of hydrogen, C 1-6 alkyl groups, aryl groups, or an ionizable functional groups and Z' is oxygen, NH or is absent, and G is carbon and g is 1, or G is sulfur and g is 2; A is an ionizable functional group independently selected from the group consisting of: -COOH, -SO 3 H, -PO 3 H 2, -N(R 1) 2, -N(R 1) 3; wherein R 1 is independently selected from the group consisting of a hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocycloalkyl and heteroaryl groups; wherein each R 1 is independently unsubstituted or substituted with one or more substituents;wherein the one or more relaxing agents cause relaxation of the hair; and wherein steps (a) and (b) are performed simultaneously.
Component for a cutting or welding torch, the component comprising a ridge forming a thread for connecting the component to other parts of the cutting or welding torch, the thread having a pressure flank (81, 91), a clearance flank (82, 92), a root flat (84, 94) and a crest flat (83, 93), wherein - an angle included by the pressure flank (81, 91) and the clearance flank (82, 92) is 60° or less, - an angle α included by the pressure flank (81, 91) and a plane perpendicular to the longitudinal axis (10, 20, 30) of the thread is 40° to 50°, - an angle β included by the clearance flank (82, 92) and a plane perpendicular to the longitudinal axis (10, 20, 30) of the thread is 0° to 20°, characterised in that - height of the ridge is 0.4 times the pitch of the thread or less. - an angle included by the pressure flank (81, 91) and the clearance flank (82, 92) is 60° or less, - an angle α included by the pressure flank (81, 91) and a plane perpendicular to the longitudinal axis (10, 20, 30) of the thread is 40° to 50°, - an angle β included by the clearance flank (82, 92) and a plane perpendicular to the longitudinal axis (10, 20, 30) of the thread is 0° to 20°, characterised in that - height of the ridge is 0.4 times the pitch of the thread or less.