A system for vertebral load and location sensing comprising: a measurement instrument (102, 400, 410, 2000, 2202, 2600, 3100) comprising: a measurement instrument shaft (430, 2010) comprising a measurement instrument proximal end and a measurement instrument distal end; a measurement instrument handle (409, 2030) coupled to the measurement instrument proximal end; and a sensored head (407, 2002) coupled to the measurement instrument distal end, the sensored head (407, 2002) comprising one or more sensors operable to measure a load applied to the one or more sensors by a muscular-skeletal system and a position of the load; an insertion instrument comprising: an insertion instrument shaft comprising an insertion instrument proximal end and an insertion instrument distal end; an insertion instrument handle coupled to the insertion instrument proximal end; and an insertion tip coupled to the insertion instrument distal end configured to receive a prosthetic component; a graphical user interface GUI and an electronic assembly (103, 401, 2024, 2212, 2626, 3104) configured to be coupled to the measurement instrument and the insertion instrument at different times; the system being characterised in that: when the electronic assembly is coupled to the measurement instrument, the electronic assembly is coupled to the one or more sensors and operable to determine a location and an orientation of the measurement instrument for use in determining a target trajectory path of the insertion instrument, wherein the target trajectory path includes an approach angle, target rotation, and trajectory path; and when the electronic assembly is coupled to the insertion instrument, the system 100 by way of GUI guides a user with the insertion instrument to recreate the target trajectory path through provision of haptic and visual feedback when the insertion instrument deviates from the target trajectory path such that the insertion instrument replicates the location and the orientation of the measurement instrument. a measurement instrument (102, 400, 410, 2000, 2202, 2600, 3100) comprising: a measurement instrument shaft (430, 2010) comprising a measurement instrument proximal end and a measurement instrument distal end; a measurement instrument handle (409, 2030) coupled to the measurement instrument proximal end; and a sensored head (407, 2002) coupled to the measurement instrument distal end, the sensored head (407, 2002) comprising one or more sensors operable to measure a load applied to the one or more sensors by a muscular-skeletal system and a position of the load; a measurement instrument shaft (430, 2010) comprising a measurement instrument proximal end and a measurement instrument distal end; a measurement instrument handle (409, 2030) coupled to the measurement instrument proximal end; and a sensored head (407, 2002) coupled to the measurement instrument distal end, the sensored head (407, 2002) comprising one or more sensors operable to measure a load applied to the one or more sensors by a muscular-skeletal system and a position of the load; an insertion instrument comprising: an insertion instrument shaft comprising an insertion instrument proximal end and an insertion instrument distal end; an insertion instrument handle coupled to the insertion instrument proximal end; and an insertion tip coupled to the insertion instrument distal end configured to receive a prosthetic component; an insertion instrument shaft comprising an insertion instrument proximal end and an insertion instrument distal end; an insertion instrument handle coupled to the insertion instrument proximal end; and an insertion tip coupled to the insertion instrument distal end configured to receive a prosthetic component; a graphical user interface GUI and an electronic assembly (103, 401, 2024, 2212, 2626, 3104) configured to be coupled to the measurement instrument and the insertion instrument at different times; the system being characterised in that: when the electronic assembly is coupled to the measurement instrument, the electronic assembly is coupled to the one or more sensors and operable to determine a location and an orientation of the measurement instrument for use in determining a target trajectory path of the insertion instrument, wherein the target trajectory path includes an approach angle, target rotation, and trajectory path; and when the electronic assembly is coupled to the insertion instrument, the system 100 by way of GUI guides a user with the insertion instrument to recreate the target trajectory path through provision of haptic and visual feedback when the insertion instrument deviates from the target trajectory path such that the insertion instrument replicates the location and the orientation of the measurement instrument. when the electronic assembly is coupled to the measurement instrument, the electronic assembly is coupled to the one or more sensors and operable to determine a location and an orientation of the measurement instrument for use in determining a target trajectory path of the insertion instrument, wherein the target trajectory path includes an approach angle, target rotation, and trajectory path; and when the electronic assembly is coupled to the insertion instrument, the system 100 by way of GUI guides a user with the insertion instrument to recreate the target trajectory path through provision of haptic and visual feedback when the insertion instrument deviates from the target trajectory path such that the insertion instrument replicates the location and the orientation of the measurement instrument.