A medical device for occluding a left atrial appendage, comprising: an expandable member (302, 402, 502) having a first end region (312, 412, 513) and a second end region (314, 414, 515), the expandable member comprising at least one inflation cavity (308, 334, 408, 434, 508) and at least one valve member (322, 332, 422, 432) configured to selectively seal the at least one inflation cavity; a first inflation media (370, 468) disposed within the at least one inflation cavity; a second inflation media (368, 474) disposed within the at least one inflation cavity, the second inflation media different than the first inflation media; wherein the expandable member is configured to expand and seal the opening of the left atrial appendage, wherein the expandable member comprises: an inner expandable member (304, 404, 504) having an inner inflation cavity (334, 434) and a first valve member (332, 432) configured to selectively seal the inner inflation cavity; and an outer expandable member (306, 406, 506) having an outer inflation cavity (308, 408, 508) and a second valve member (322, 422) configured to selectively seal the outer inflation cavity the inner expandable member being disposed within the outer inflation cavity, wherein a plurality of apertures extend from an inner surface to an outer surface of the outer expandable member (306, 406, 306), and wherein the outer expandable member (306, 406, 506) is configured to receive the first inflation media (370, 468) and the inner expandable member (304, 404, 504) is configured to receive the second inflation media (368, 474) an expandable member (302, 402, 502) having a first end region (312, 412, 513) and a second end region (314, 414, 515), the expandable member comprising at least one inflation cavity (308, 334, 408, 434, 508) and at least one valve member (322, 332, 422, 432) configured to selectively seal the at least one inflation cavity; a first inflation media (370, 468) disposed within the at least one inflation cavity; a second inflation media (368, 474) disposed within the at least one inflation cavity, the second inflation media different than the first inflation media; wherein the expandable member is configured to expand and seal the opening of the left atrial appendage, wherein the expandable member comprises: an inner expandable member (304, 404, 504) having an inner inflation cavity (334, 434) and a first valve member (332, 432) configured to selectively seal the inner inflation cavity; and an outer expandable member (306, 406, 506) having an outer inflation cavity (308, 408, 508) and a second valve member (322, 422) configured to selectively seal the outer inflation cavity the inner expandable member being disposed within the outer inflation cavity, an inner expandable member (304, 404, 504) having an inner inflation cavity (334, 434) and a first valve member (332, 432) configured to selectively seal the inner inflation cavity; and an outer expandable member (306, 406, 506) having an outer inflation cavity (308, 408, 508) and a second valve member (322, 422) configured to selectively seal the outer inflation cavity the inner expandable member being disposed within the outer inflation cavity, wherein a plurality of apertures extend from an inner surface to an outer surface of the outer expandable member (306, 406, 306), and wherein the outer expandable member (306, 406, 506) is configured to receive the first inflation media (370, 468) and the inner expandable member (304, 404, 504) is configured to receive the second inflation media (368, 474)