mhurhangee/ep-ind-claims huggingface dataset:
A single-use injector having a piston actuation ram which is mounted in a housing, is loaded by means of a spring energy store, and can be released by means of a displaceable triggering device, wherein the piston actuation ram can be supported by means of a tension bar which is mounted in the housing, characterised in that - the triggering device comprises a triggering ring displaceable relative to the housing, - the tension bar can be supported directly or indirectly by means of a bearing face of the triggering ring, and - the bearing face encloses an angle between 10 degrees and 45 degrees with the longitudinal direction of the single-use injector, wherein the apex of the angle is offset in the triggering direction of the single-use injector relative to the triggering ring. - the triggering device comprises a triggering ring displaceable relative to the housing, - the tension bar can be supported directly or indirectly by means of a bearing face of the triggering ring, and - the bearing face encloses an angle between 10 degrees and 45 degrees with the longitudinal direction of the single-use injector, wherein the apex of the angle is offset in the triggering direction of the single-use injector relative to the triggering ring.
A process for obtaining recombinant factor VIII protein with improved activity, said process comprising acts of: a. introducing polynucleotide sequence consisting of SEQ ID NO. 1 or polynucleotide sequence consisting of SEQ ID NO. 3 into a non-filamentous fungi host cell to obtain both corresponding polypeptides individually; or b. introducing vector comprising polynucleotide sequence consisting of SEQ ID NO. 1 or polynucleotide sequence consisting of SEQ ID NO.3 into a non-filamentous fungi host cell to obtain corresponding polypeptides individually; and c. reconstituting the polypeptides produced by step (a) or (b) to obtain the recombinant Factor VIII protein. a. introducing polynucleotide sequence consisting of SEQ ID NO. 1 or polynucleotide sequence consisting of SEQ ID NO. 3 into a non-filamentous fungi host cell to obtain both corresponding polypeptides individually; or b. introducing vector comprising polynucleotide sequence consisting of SEQ ID NO. 1 or polynucleotide sequence consisting of SEQ ID NO.3 into a non-filamentous fungi host cell to obtain corresponding polypeptides individually; and c. reconstituting the polypeptides produced by step (a) or (b) to obtain the recombinant Factor VIII protein.
A complex comprising a radionuclide and a compound represented by A: wherein R represents H, alkyl, hydroxyalkyl, alkoxyalkyl, aminoalkyl, thioalkyl, alkenyl, alkynyl, aryl, heteroaryl, aralkyl, heteroaralkyl, acyl, aminoacyl, hydroxyacyl, thioacyl, -CO 2 H, -(CH 2) d -R 80, or an amino acid radical; wherein said radionuclide is technetium or rhenium; R 80 represents independently for each occurrence carboxaldehyde, carboxylate, carboxamido, alkoxycarbonyl, aryloxycarbonyl, ammonium, aryl, heteroaryl, cycloalkyl, cycloalkenyl, heterocyclyl, polycyclyl, amino acid, peptide, saccharide, ribonucleic acid, (deoxy)ribonucleic acid, or ligand for a G-protein-coupled receptor; and d is an integer in the range 0 to 12 inclusive.
Device for producing a profile from a half-finished product made of sheet metal, namely a predefined profile having a variable height and/or width and having at least two legs (1, 1'; 2, 2', 2"; 3, 3', 3") extending in its longitudinal direction and angled with respect to each other on its cross-sectional plane, with a first leg (1, 1') thereof having a partly uneven shape, the device having a molded plank defining the predefined profile for supporting one of the legs (1, 1') over its entire surface and an upper molded plank adapted to firmly clamp a portion of the half-finished product, which forms the first leg (1, 1') of the predefined profile, between itself and the lower molded plank; the mutually facing surfaces of the two molded planks (6, 7) being uneven und mutually complementary and having the same shape as the first leg (1, 1') of the predefined profile, and the device having at least one roller (17, 27) for rollforming the half-finished product supported by the lower molded plank to form the predefined profile; characterized in that at least the lower molded plank is mounted on a carriage which is horizontally movable on a platform along a straight path and an adjustment stand (14, 24) is mounted on the platform on at least one side of the path and the adjustment stand contains a base (15, 25) which is vertically movable and to which the at least one roller (17, 27) is rotatably mounted. the device having a molded plank defining the predefined profile for supporting one of the legs (1, 1') over its entire surface and an upper molded plank adapted to firmly clamp a portion of the half-finished product, which forms the first leg (1, 1') of the predefined profile, between itself and the lower molded plank; the mutually facing surfaces of the two molded planks (6, 7) being uneven und mutually complementary and having the same shape as the first leg (1, 1') of the predefined profile, and the device having at least one roller (17, 27) for rollforming the half-finished product supported by the lower molded plank to form the predefined profile; characterized in that at least the lower molded plank is mounted on a carriage which is horizontally movable on a platform along a straight path and an adjustment stand (14, 24) is mounted on the platform on at least one side of the path and the adjustment stand contains a base (15, 25) which is vertically movable and to which the at least one roller (17, 27) is rotatably mounted. characterized in that at least the lower molded plank is mounted on a carriage which is horizontally movable on a platform along a straight path and an adjustment stand (14, 24) is mounted on the platform on at least one side of the path and the adjustment stand contains a base (15, 25) which is vertically movable and to which the at least one roller (17, 27) is rotatably mounted.
A control device (10, 10a) for a gas turbine including a plurality of combustors, comprising: a prediction unit (11, 11a) which is configured to determine the number and arrangement of combustors required for achieving a target load on the basis of a learned model in which a relationship between a load and the number and arrangement of combustors to ignite is defined; and a control unit which is configured to select and ignite the combustors determined by the prediction unit (11, 11a). a prediction unit (11, 11a) which is configured to determine the number and arrangement of combustors required for achieving a target load on the basis of a learned model in which a relationship between a load and the number and arrangement of combustors to ignite is defined; and a control unit which is configured to select and ignite the combustors determined by the prediction unit (11, 11a).
A method comprising: obtaining a code to be printed on one or more products by a laser marking device configured to direct a laser beam in two orthogonal directions to move between different locations and to dwell at the different locations to form marks on the one or more products; grouping discrete symbols in the code with each other into separate symbol groups (402, 404, 406, 408) based on locations of the discrete symbols in the code; organizing the separate symbol groups into one or more macro-level stripes (412, 414) in a direction perpendicular to a direction of motion of the one or more products in a product line configured to move products through a facility; organizing one or more symbols in each respective symbol group into one or more stripes (220, 222, 224, 226, 228) in the direction perpendicular to the direction of motion; adding an extra distance or a time delay between stripes in at least one of the separate symbol groups to prevent clipping of a symbol by the laser marking device due to a print aperture of the laser marking device; and causing the laser marking device to direct the laser beam in accordance with the separate symbol groups, including using the extra distance or the time delay between the stripes in the at least one of the separate symbol groups. obtaining a code to be printed on one or more products by a laser marking device configured to direct a laser beam in two orthogonal directions to move between different locations and to dwell at the different locations to form marks on the one or more products; grouping discrete symbols in the code with each other into separate symbol groups (402, 404, 406, 408) based on locations of the discrete symbols in the code; organizing the separate symbol groups into one or more macro-level stripes (412, 414) in a direction perpendicular to a direction of motion of the one or more products in a product line configured to move products through a facility; organizing one or more symbols in each respective symbol group into one or more stripes (220, 222, 224, 226, 228) in the direction perpendicular to the direction of motion; adding an extra distance or a time delay between stripes in at least one of the separate symbol groups to prevent clipping of a symbol by the laser marking device due to a print aperture of the laser marking device; and causing the laser marking device to direct the laser beam in accordance with the separate symbol groups, including using the extra distance or the time delay between the stripes in the at least one of the separate symbol groups.
A composite profile, comprising - a first profile having at least one insulating strip receiver, - at least one second profile having at least one insulating strip receiver, - at least one insulating strip having one first connecting section and at least one second connecting section, wherein - the first connecting section is accommodated in the insulating strip receiver of the first profile and the second connecting section is accommodated in the insulating strip receiver of the second profile, wherein - the at least one insulating strip receiver of the second profile and the second connecting section of the at least one insulating strip form a shear-resilient connection, wherein the shear-resilient connection is formed by at least one bulge in the insulating strip and at least one recess in the accommodated connecting section, wherein the at least one bulge engages with the at least one recess, wherein the at least one insulating strip receiver of the first profile and the first connecting section of the at least one insulating strip form a shear-resistant connection, characterized in that the at least one bulge is a semi-spherical bulge. - a first profile having at least one insulating strip receiver, - at least one second profile having at least one insulating strip receiver, - at least one insulating strip having one first connecting section and at least one second connecting section, wherein - the first connecting section is accommodated in the insulating strip receiver of the first profile and the second connecting section is accommodated in the insulating strip receiver of the second profile, wherein - the at least one insulating strip receiver of the second profile and the second connecting section of the at least one insulating strip form a shear-resilient connection, wherein
Process for the preparation of fluoroalkylnitriles of the general formula by catalytic gas-phase dehydration, in which X 1 and X 2 are, independently of each other, a halogen, hydrogen or methyl, characterized in that fluorinated carboxamides of the formula in which X 1 and X 2 have the abovementioned meanings, are converted into the gas phase and are reacted in the presence of catalysts from the group of zeolites, aluminium phosphate, zirconium dioxide and heteropolyacids. X 1 and X 2 are, independently of each other, a halogen, hydrogen or methyl, characterized in that fluorinated carboxamides of the formula in which X 1 and X 2 have the abovementioned meanings, are converted into the gas phase and are reacted in the presence of catalysts from the group of zeolites, aluminium phosphate, zirconium dioxide and heteropolyacids.
An apparatus for densifying and compacting granular materials comprising a drive shaft, a compaction chamber at a lower end of the drive shaft, and one or more diametric expansion and restriction elements, wherein the apparatus further comprises an opening in an upper surface of the compaction chamber comprising a flow-through passage exterior of the drive shaft and configured for accepting granular materials from outside of the drive shaft.
A driving domain management unit that manages a driving domain for an autonomous vehicle, comprising: a change pattern setting portion that selects one of a plurality of typical patterns previously stored and patterning autonomously drivable domains based on input information changing in time series to determine a driving permission domain permitting autonomous driving of the vehicle; a driving condition monitor portion that collects event related information about an event causing deterioration of a road condition from an outside (120, 130) to determine the event based on the collected event related information; an exclusion domain management portion that determines an exclusion domain prohibiting autonomous driving of the vehicle in preference to the driving permission domain indicated by the typical pattern based on a result of the determination by the driving condition monitor portion and on position information about the event included in the event related information used for the determination; a distribution portion that distributes the typical pattern selected by the change pattern setting portion and the information about the exclusion domain determined by the exclusion domain management portion or the change pattern and the information based on the exclusion domain; and a data storage portion that stores the multiple typical patterns and the information about the exclusion domain. a change pattern setting portion that selects one of a plurality of typical patterns previously stored and patterning autonomously drivable domains based on input information changing in time series to determine a driving permission domain permitting autonomous driving of the vehicle; a driving condition monitor portion that collects event related information about an event causing deterioration of a road condition from an outside (120, 130) to determine the event based on the collected event related information; an exclusion domain management portion that determines an exclusion domain prohibiting autonomous driving of the vehicle in preference to the driving permission domain indicated by the typical pattern based on a result of the determination by the driving condition monitor portion and on position information about the event included in the event related information used for the determination; a distribution portion that distributes the typical pattern selected by the change pattern setting portion and the information about the exclusion domain determined by the exclusion domain management portion or the change pattern and the information based on the exclusion domain; and a data storage portion that stores the multiple typical patterns and the information about the exclusion domain.
A powder comprising core/shell particles having an average particle size of less than 1000 microns, each particle comprising: a liquid core that is substantially free of water, wherein substantially free means 5% by weight or less, and comprises A) a polar liquid having a percent surface polarity of at least 24%, wherein the percent surface polarity is measured using the method described in the description; B) a basic active agent, wherein the basic active agent is selected from the group consisting of minoxidil, finasteride, lumigan and mixtures thereof, and C) from about 0.1% to about 20% by weight of at least one acidic solubility enhancing agent that is not an active ingredient; and a shell comprising hydrophobic particles. a liquid core that is substantially free of water, wherein substantially free means 5% by weight or less, and comprises A) a polar liquid having a percent surface polarity of at least 24%, wherein the percent surface polarity is measured using the method described in the description; B) a basic active agent, wherein the basic active agent is selected from the group consisting of minoxidil, finasteride, lumigan and mixtures thereof, and C) from about 0.1% to about 20% by weight of at least one acidic solubility enhancing agent that is not an active ingredient; and A) a polar liquid having a percent surface polarity of at least 24%, wherein the percent surface polarity is measured using the method described in the description; B) a basic active agent, wherein the basic active agent is selected from the group consisting of minoxidil, finasteride, lumigan and mixtures thereof, and C) from about 0.1% to about 20% by weight of at least one acidic solubility enhancing agent that is not an active ingredient; and a shell comprising hydrophobic particles.
A computer-implemented method for controlling access to data, the method being performed by a computing system comprising at least one processor, the computer-implemented method comprising: receiving a request to access data stored in a deactivated virtualization layer that mirrors a directory structure of an underlying file system; analyzing a computing device to determine whether the computing device meets a condition specified by an access-control policy that requires the condition to be met before access to the data stored in the deactivated virtualization layer is allowed; determining, based on the analysis of the computing device, that the access-control policy is satisfied; activating, by overlaying the virtualization layer over a file system, the virtualization layer to allow access to the data in response to the determination that the access-control policy is satisfied. receiving a request to access data stored in a deactivated virtualization layer that mirrors a directory structure of an underlying file system; analyzing a computing device to determine whether the computing device meets a condition specified by an access-control policy that requires the condition to be met before access to the data stored in the deactivated virtualization layer is allowed; determining, based on the analysis of the computing device, that the access-control policy is satisfied; activating, by overlaying the virtualization layer over a file system, the virtualization layer to allow access to the data in response to the determination that the access-control policy is satisfied.
A pharmaceutical composition comprising an antagonist of human CLEC-1 and a pharmaceutical acceptable excipient, for use in the treatment of a human subject suffering from cancer.
Floor panel for forming a floor covering, wherein the floor panel comprises a layer-shaped substrate, as well as a decorative top layer situated above the substrate; wherein the substrate comprises at least a layer which is realized on the basis of a composition comprising at least a thermoplastic synthetic material; wherein the floor panel, on at least two opposite edges, is provided with mechanical coupling means or coupling parts, said coupling means or coupling parts being realized in the substrate layer; and wherein these coupling means or coupling parts allow that two of such floor panels can be coupled to each other in such a manner that a locking is created in a direction perpendicular to the plane of the coupled floor panels, as well as in a direction perpendicular to the coupled edges and in the plane of the coupled floor panels; characterized in that the composition, apart from the thermoplastic synthetic material, also comprises at least one or more elastomers, and in that said thermoplastic synthetic material concerns thermoplastic polyester.
A process of producing methyl methacrylate or methacrylic acid comprising the steps of; (i) converting 2-butanone to methyl propionate using a Baeyer-Villiger monooxygenase, and (ii) treating the methyl propionate produced to obtain methyl methacrylate or methacrylic acid; wherein the Baeyer-Villiger monooxygenase is selected from a cyclohexanone monoxygenase, a 4-hydroxyacetophenone monooxygenase, or a cyclopentadecanone monooxygenase. (i) converting 2-butanone to methyl propionate using a Baeyer-Villiger monooxygenase, and (ii) treating the methyl propionate produced to obtain methyl methacrylate or methacrylic acid;
A product comprising a copolymer, said copolymer comprising (a) one or more pendant group segments and (b) one or more polyol segments, each of said segments being linked to one or more further segments which may be the same or different, wherein said one or more pendant group segments are the same or different and are siloxane segments comprising a silsesquioxane cage or partial silsesquioxane cage, and wherein in the copolymer the ratio of pendant siloxane segment(s) to polyol segment(s) is 1:X wherein X is 10 or more, and wherein at least a part of each of said pendant group segment(s) is on a side chain of the copolymer, and wherein the product is a product for medical use selected from a moulded article, an implantable device, a contact lens, or a surgical device.
A storage interposer module, comprising: a host connector configured to couple to one or more host systems (120, 121) over associated host Peripheral Component Interconnect Express, herein referred to as PCIe, interfaces; PCIe switch circuitry configured to receive storage operations over the host connector that are issued by the one or more host systems (120, 121) and transfer the storage operations for storage by one or more storage devices over drive PCIe interfaces; and an interposer control module configured to monitor the storage operations in the PCIe switch circuitry via a control interface coupled between the PCIe switch circuitry and the interposer control module, selectively direct delivery of each of the storage operations to corresponding storage areas among the one or more storage devices based at least on addressing information monitored about the storage operations in the PCIe switch circuitry, and characterized in that, in response to detecting a power loss that affects the one or more storage devices, the interposer control module is configured to emulate one or more of the host systems (120, 121) to inject PCIe control traffic onto the drive PCIe interfaces of the storage devices to control a data commit process of the one or more storage devices. a host connector configured to couple to one or more host systems (120, 121) over associated host Peripheral Component Interconnect Express, herein referred to as PCIe, interfaces; PCIe switch circuitry configured to receive storage operations over the host connector that are issued by the one or more host systems (120, 121) and transfer the storage operations for storage by one or more storage devices over drive PCIe interfaces; and an interposer control module configured to monitor the storage operations in the PCIe switch circuitry via a control interface coupled between the PCIe switch circuitry and the interposer control module, selectively direct delivery of each of the storage operations to corresponding storage areas among the one or more storage devices based at least on addressing information monitored about the storage operations in the PCIe switch circuitry, and characterized in that, in response to detecting a power loss that affects the one or more storage devices, the interposer control module is configured to emulate one or more of the host systems (120, 121) to inject PCIe control traffic onto the drive PCIe interfaces of the storage devices to control a data commit process of the one or more storage devices.