An extrusion press for continuous production of profiles from an extrudable material, comprising - a base frame, - at least one friction wheel that can be rotated about a drive axis, which is provided at least with one peripheral groove, the friction wheel being in drive connection with a drive unit, - at least one pinch roller, - a tool holding device, which is mounted at a swivel axis on the base frame and can be swiveled about the swivel axis between a working position and a release position, wherein the tool holding device, as viewed in the passage direction of the profile to be manufactured, is arranged after the friction wheel, - a locking device, which in its locking position keeps the tool holding device locked in its working position with respect to the base frame, - at least one tool unit, which is supported at the tool holding device, - wherein a gap is formed between the tool unit and the friction wheel in case the tool holding device is present in the working position, characterized in that - at the base frame, a setting device is arranged in an end area of the tool holding device which is distanced from the swivel axis as well as lying opposite with respect to the drive axis of the friction wheel, which setting device has a setting element formed to be adjustable with respect to the base frame with a setting surface facing the end area of the tool holding device as well as a guide surface facing away from the tool holding device, - the setting surface and the guide surface are aligned to be wedge-shaped to each other, - the tool holding device has a support surface at its end area distanced from the swivel axis as well as at a first side facing the friction wheel, wherein in the working position of the tool holding device, the support surface is supported at the setting surface of the setting element, - the locking device has at least one pressure unit with at least one pressure element, which pressure element is arranged also at the end area distanced from the swivel axis when the tool holding device is in working position, but is in contact with the tool holding device at a second side facing away from the friction wheel, and the support surface of the tool holding device is pressed against the setting surface of the setting element by means of the pressure unit, - the gap formed between the tool unit and the friction wheel can be changed by adjusting the setting element in its gap width. - a base frame, - at least one friction wheel that can be rotated about a drive axis, which is provided at least with one peripheral groove, the friction wheel being in drive connection with a drive unit, - at least one pinch roller, - a tool holding device, which is mounted at a swivel axis on the base frame and can be swiveled about the swivel axis between a working position and a release position, wherein the tool holding device, as viewed in the passage direction of the profile to be manufactured, is arranged after the friction wheel, - a locking device, which in its locking position keeps the tool holding device locked in its working position with respect to the base frame, - at least one tool unit, which is supported at the tool holding device, - wherein a gap is formed between the tool unit and the friction wheel in case the tool holding device is present in the working position, characterized in that - at the base frame, a setting device is arranged in an end area of the tool holding device which is distanced from the swivel axis as well as lying opposite with respect to the drive axis of the friction wheel, which setting device has a setting element formed to be adjustable with respect to the base frame with a setting surface facing the end area of the tool holding device as well as a guide surface facing away from the tool holding device, - the setting surface and the guide surface are aligned to be wedge-shaped to each other, - the tool holding device has a support surface at its end area distanced from the swivel axis as well as at a first side facing the friction wheel, wherein in the working position of the tool holding device, the support surface is supported at the setting surface of the setting element, - the locking device has at least one pressure unit with at least one pressure element, which pressure element is arranged also at the end area distanced from the swivel axis when the tool holding device is in working position, but is in contact with the tool holding device at a second side facing away from the friction wheel, and the support surface of the tool holding device is pressed against the setting surface of the setting element by means of the pressure unit, - the gap formed between the tool unit and the friction wheel can be changed by adjusting the setting element in its gap width.