A percutaneous transluminal angioplasty device, comprising: a multi-lumen catheter having a proximal portion and a distal portion, the catheter defining a first lumen, a second lumen, and a third lumen, each lumen extending through at least a portion of the catheter; a filter disposed adjacent the end of the distal portion of the catheter, and being movable between unexpanded and expanded configuration, the filter comprising a filter frame and a filter membrane, said frame formed of a shape memory material having a memory of the unexpanded configuration, wherein the filter frame has a distal end and a proximal end, the proximal end of the filter frame being fixedly coupled to the catheter, and the distal end of the filter frame being slidably coupled to the catheter, wherein the filter membrane has a distal end and proximal end, and the distal end of the filter membrane is fixedly coupled to the catheter distally of the proximal end of the filter membrane an the distal end of the filter frame, and the proximal end of the filter membrane is fixedly coupled to a portion of the filter frame; a filter activation wire disposed within the first lumen, wherein a distal end of the filter activation wire is coupled to the distal end of the filter frame, and wherein tensioning the filter activation wire in a proximal direction urges the distal end of the filter frame in an axial proximal direction from an unexpanded configuration to an expanded configuration; an expandable balloon disposed between the filter frame and the proximal end of the distal portion of the catheter; and a self-expanding stent (100, 280, 400, 500, 600)extending over at least a portion of the expandable balloon; and a movable sheath extending over at least a portion of the self-expanding stent (100, 280, 400, 500, 600); a sheath wire coupled to the movable sheath, the sheath wire extending through one of the lumens defined by the catheter, wherein movement of the sheath wire translates the sheath axially; and a handle coupled to a proximal end of the catheter, wherein the handle comprises a first actuation knob coupled to the filter activation wire and being manipulatable to expand and contract the filter via the filter activation wire, and wherein the handle further comprises a second actuation knob coupled to the sheath wire and being manipulatable to axially move the sheath via the sheath wire. a multi-lumen catheter having a proximal portion and a distal portion, the catheter defining a first lumen, a second lumen, and a third lumen, each lumen extending through at least a portion of the catheter; a filter disposed adjacent the end of the distal portion of the catheter, and being movable between unexpanded and expanded configuration, the filter comprising a filter frame and a filter membrane, said frame formed of a shape memory material having a memory of the unexpanded configuration, wherein the filter frame has a distal end and a proximal end, the proximal end of the filter frame being fixedly coupled to the catheter, and the distal end of the filter frame being slidably coupled to the catheter, wherein the filter membrane has a distal end and proximal end, and the distal end of the filter membrane is fixedly coupled to the catheter distally of the proximal end of the filter membrane an the distal end of the filter frame, and the proximal end of the filter membrane is fixedly coupled to a portion of the filter frame; a filter activation wire disposed within the first lumen, wherein a distal end of the filter activation wire is coupled to the distal end of the filter frame, and wherein tensioning the filter activation wire in a proximal direction urges the distal end of the filter frame in an axial proximal direction from an unexpanded configuration to an expanded configuration; an expandable balloon disposed between the filter frame and the proximal end of the distal portion of the catheter; and a self-expanding stent (100, 280, 400, 500, 600)extending over at least a portion of the expandable balloon; and a movable sheath extending over at least a portion of the self-expanding stent (100, 280, 400, 500, 600); a sheath wire coupled to the movable sheath, the sheath wire extending through one of the lumens defined by the catheter, wherein movement of the sheath wire translates the sheath axially; and a handle coupled to a proximal end of the catheter, wherein the handle comprises a first actuation knob coupled to the filter activation wire and being manipulatable to expand and contract the filter via the filter activation wire, and wherein the handle further comprises a second actuation knob coupled to the sheath wire and being manipulatable to axially move the sheath via the sheath wire.