mhurhangee/ep-ind-claims huggingface dataset:
A device (10, 50, 90) for processing a biological material comprising: a. a syringe barrel (12, 52, 92) having an inner diameter (14, 54, 94) symmetrical about a longitudinal axis (16, 56, 96), an open end (18, 58, 98), a closed end (20, 60, 100), and an outlet (22, 62,102) at the closed end; b. desiccating beads (26, 64, 106) positioned within the barrel; c. a filter (28, 82, 108) positioned at the closed end of the barrel; and d. a plunger (30, 66, 110) insertable into the barrel through the open end (18, 58, 98), the plunger including: an exterior portion (32, 68, 112) extending from within the syringe barrel (12, 52, 92); and, a paddle assembly (40, 76,120) fixed to the plunger (30, 66, 110) and, in use, completely located within the syringe barrel (12, 52, 92) between the plunger and the filter (28,108) or between the plunger and the closed end, the paddle assembly (40, 76, 120) configured to collapse or break into a plurality of pieces when the plunger (30, 66, 110) is depressed and the paddle assembly is pressed against the filter (28, 108) or the closed end, wherein the paddle assembly (40, 76,120) is configured to mix the biological material with the desiccating beads (26, 64,106). a. a syringe barrel (12, 52, 92) having an inner diameter (14, 54, 94) symmetrical about a longitudinal axis (16, 56, 96), an open end (18, 58, 98), a closed end (20, 60, 100), and an outlet (22, 62,102) at the closed end; b. desiccating beads (26, 64, 106) positioned within the barrel; c. a filter (28, 82, 108) positioned at the closed end of the barrel; and d. a plunger (30, 66, 110) insertable into the barrel through the open end (18, 58, 98), the plunger including: an exterior portion (32, 68, 112) extending from within the syringe barrel (12, 52, 92); and, a paddle assembly (40, 76,120) fixed to the plunger (30, 66, 110) and, in use, completely located within the syringe barrel (12, 52, 92) between the plunger and the filter (28,108) or between the plunger and the closed end, the paddle assembly (40, 76, 120) configured to collapse or break into a plurality of pieces when the plunger (30, 66, 110) is depressed and the paddle assembly is pressed against the filter (28, 108) or the closed end, an exterior portion (32, 68, 112) extending from within the syringe barrel (12, 52, 92); and, a paddle assembly (40, 76,120) fixed to the plunger (30, 66, 110) and, in use, completely located within the syringe barrel (12, 52, 92) between the plunger and the filter (28,108) or between the plunger and the closed end, the paddle assembly (40, 76, 120) configured to collapse or break into a plurality of pieces when the plunger (30, 66, 110) is depressed and the paddle assembly is pressed against the filter (28, 108) or the closed end,
A tooling assembly for mounting a component in a powder bed additive manufacturing machine, the tooling assembly comprising: a component fixture configured for receiving the component; a mounting plate configured for receiving the component fixture; and a magnet assembly operably coupling the mounting plate to the component fixture for securing the component fixture to the mounting plate in a desired orientation. a component fixture configured for receiving the component; a mounting plate configured for receiving the component fixture; and a magnet assembly operably coupling the mounting plate to the component fixture for securing the component fixture to the mounting plate in a desired orientation.
A pharmaceutical composition comprising: a controlled release phase I comprising an effective amount of flurbiprofen or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable excipient; and a controlled release or immediate release phase II comprising an effective amount of tizanidine or thiocolchicoside or a salt thereof, and a pharmaceutically acceptable excipient.
A recombinant expression vector comprising a nucleotide sequence encoding a T cell receptor comprising the alpha chain complementarity determining region 1 amino acid sequence of SEQ ID NO: 3, the alpha chain CDR2 amino acid sequence of SEQ ID NO: 4, the alpha chain CDR3 amino acid sequence of SEQ ID NO: 5, the beta chain CDR1 amino acid sequence of SEQ ID NO: 6, the beta chain CDR2 amino acid sequence of SEQ ID NO: 7, and the beta chain CDR3 amino acid sequence of SEQ ID NO: 8 and having antigenic specificity for human papillomavirus 16 E7 11-19 SEQ ID NO: 2, optionally wherein the TCR: (i) comprises a human constant region; (ii) comprises a human variable region and a murine constant region; or (iii) comprises the amino acid sequences of (a) SEQ ID NO: 9 and (b) SEQ ID NO: 10, wherein X at position 2 is Ala or Gly. (i) comprises a human constant region; (ii) comprises a human variable region and a murine constant region; or (iii) comprises the amino acid sequences of (a) SEQ ID NO: 9 and (b) SEQ ID NO: 10, wherein X at position 2 is Ala or Gly.
Device for separating a flowing medium comprising mixture into at least two fractions with differing mass density, comprising: - a plurality of plates disposed parallel to each other, and - a frame engaging at least substantially round the plates, wherein the plates disposed parallel to each other are provided with coupling openings, through which coupling openings is inserted at least one elongate coupling member which, in a direction perpendicularly of the axial of the elongate coupling member, has an asymmetrical cross-section at positions located between the plates which varies from a circle-symmetrical section, characterized in that the elongate coupling member: A) is insertable through the openings in a specific insert rotation position, and B) turned around the axial relative to the insert rotation position to a distant keeping rotational position determines the distance between the plates in fixed manner. - a plurality of plates disposed parallel to each other, and - a frame engaging at least substantially round the plates, A) is insertable through the openings in a specific insert rotation position, and B) turned around the axial relative to the insert rotation position to a distant keeping rotational position determines the distance between the plates in fixed manner.
An intaglio printing press comprising: - a stationary machine frame supporting an intaglio printing cylinder and an impression cylinder contacting said intaglio printing cylinder; - an inking system (12, 13, 16) for inking the intaglio printing cylinder, which inking system (12, 13, 16) comprises an ink-collecting cylinder designed to contact said intaglio printing cylinder and at least one inking device (13, 16) for supplying ink to said ink-collecting cylinder; and - at least a first mobile carriage supporting said ink-collecting cylinder, which first mobile carriage is adapted to be moved with respect to said stationary machine frame between a working position where the ink-collecting cylinder contacts the intaglio printing cylinder and a retracted position where the ink-collecting cylinder is retracted away from the intaglio printing cylinder, characterized in that the axis of rotation of the ink-collecting cylinder lies below a horizontal plane containing the axis of rotation of the intaglio printing cylinder, and in that a plane containing the axis of rotation of the ink-collecting cylinder and the axis of rotation of the intaglio printing cylinder forms, in the working position of the first mobile carriage, an acute angle with respect to the horizontal plane. - a stationary machine frame supporting an intaglio printing cylinder and an impression cylinder contacting said intaglio printing cylinder; - an inking system (12, 13, 16) for inking the intaglio printing cylinder, which inking system (12, 13, 16) comprises an ink-collecting cylinder designed to contact said intaglio printing cylinder and at least one inking device (13, 16) for supplying ink to said ink-collecting cylinder; and - at least a first mobile carriage supporting said ink-collecting cylinder, which first mobile carriage is adapted to be moved with respect to said stationary machine frame between a working position where the ink-collecting cylinder contacts the intaglio printing cylinder and a retracted position where the ink-collecting cylinder is retracted away from the intaglio printing cylinder,
Device for comminuting or grinding material to be ground, in particular hard, brittle or embrittled particles or substances, having a container for receiving the material to be ground and having a tool, which rotates in said container during comminution or grinding, and having a drive for said tool, wherein the container together with the tool can be releasably coupled to the drive, and the tool is disposed in the container in a position released or decoupled from the drive and/or is loosely rotatable and, in the usage position, is connected for conjoint rotation with the drive and centred by the coupling, characterised in that a shaft engaging with the tool extends outwards or downwards through the bottom or a wall of the container and has or carries a coupling protrusion which can be plugged together in a centring and non-positive or positive manner with a counter coupling piece disposed on the drive for conjoint rotation therewith, that the coupling protrusion and the counter coupling piece can be latched by means of outwardly or radially protruding projections and matching apertures which are open in the axial direction and have undercuts, and that the aperture provided for latching with the respective projection is disposed at a point of the coupling at which the coupling protrusion and the counter coupling piece are held together by a reciprocal axial force, and the bottom region or wall region of the container adjacent to the coupling protrusion are pressed against a seal surrounding the shaft.
A control device used in a delivery system having an automatic movement device that automatically moves an article inside a specific space and delivering the article, the control device comprising: a storage section configured to store schedule information including at least one of change information including a change region in which a movable region, that is a region in which the automatic movement device is movable, of the automatic movement device is changed in the specific space and a change time at which the region is changed, and operation information including an operation time at which the automatic movement device starts operating; and a processing control section configured to perform processing of preparing a usage map used by the automatic movement device by adding a change to a reference map of the specific space, based on the schedule information, wherein the processing control section prepares the usage map by reflecting the change region included in the schedule information on the reference map, based on the change time included in the schedule information. a storage section configured to store schedule information including at least one of change information including a change region in which a movable region, that is a region in which the automatic movement device is movable, of the automatic movement device is changed in the specific space and a change time at which the region is changed, and operation information including an operation time at which the automatic movement device starts operating; and a processing control section configured to perform processing of preparing a usage map used by the automatic movement device by adding a change to a reference map of the specific space, based on the schedule information, wherein the processing control section prepares the usage map by reflecting the change region included in the schedule information on the reference map, based on the change time included in the schedule information.
An inhibitor of antithrombin III for use in the treatment and prevention of bleeding: i) in a subject suffering from an acquired or genetic bleeding disorder (hypocoagulability); or, ii) in a subject having a clinical condition characterised by excessive bleeding, wherein the bleeding is not due to the use of anti-coagulants; wherein the inhibitor is selected from the group consisting of: a) a peptide or peptidomimetic that mimicks the amino acid sequence of RSL residues P1-P14; b) an aptamer that specifically binds to antithrombin III; and, c) an antibody or antibody fragment that specifically binds to antithrombin III, and wherein the inhibitor, when added to pooled plasma from healthy volunteers, causes a decrease of functional antithrombin III levels by at least 20% as measured with a chromogenic assay for functional antithrombin III using factor Xa or thrombin. i) in a subject suffering from an acquired or genetic bleeding disorder (hypocoagulability); or, ii) in a subject having a clinical condition characterised by excessive bleeding, wherein the bleeding is not due to the use of anti-coagulants; a) a peptide or peptidomimetic that mimicks the amino acid sequence of RSL residues P1-P14; b) an aptamer that specifically binds to antithrombin III; and, c) an antibody or antibody fragment that specifically binds to antithrombin III,
A method for determining a strong classifier based on features extracted from training media segments, comprising: creating a set of feature vectors by extracting a plurality of features from a training set of media segments, each individual feature vector in the set of feature vectors comprises a plurality of features extracted from an individual segment in the training set of media segments; associating a set of reference truth labels with the training set of media segments, each individual segment in the training set of media segments is associated with an individual reference truth label in the set of reference truth labels; calculating a plurality of sets of weak classifiers, each individual set of weak classifier in the plurality of sets of weak classifiers maps the set of feature vectors to a set of predicted truth labels; determining a plurality of weights for the plurality of sets of weak classifiers, each individual set of weak classifiers in the plurality of sets of weak classifiers is given an individual weight in the plurality of weights; creating, based on the plurality of sets of weak classifiers and the plurality of weights, a strong classifier that is to be applied to media data to rank and select a representative segment in a plurality of candidate representative segments; wherein the method is performed by one or more computing devices. creating a set of feature vectors by extracting a plurality of features from a training set of media segments, each individual feature vector in the set of feature vectors comprises a plurality of features extracted from an individual segment in the training set of media segments; associating a set of reference truth labels with the training set of media segments, each individual segment in the training set of media segments is associated with an individual reference truth label in the set of reference truth labels; calculating a plurality of sets of weak classifiers, each individual set of weak classifier in the plurality of sets of weak classifiers maps the set of feature vectors to a set of predicted truth labels; determining a plurality of weights for the plurality of sets of weak classifiers, each individual set of weak classifiers in the plurality of sets of weak classifiers is given an individual weight in the plurality of weights; creating, based on the plurality of sets of weak classifiers and the plurality of weights, a strong classifier that is to be applied to media data to rank and select a representative segment in a plurality of candidate representative segments; wherein the method is performed by one or more computing devices.
A method comprising: welding a first end of a base to a first end (110, 212) of a first work piece (102, 202, 402, 806) having a first content of a metallic element, the base having a same content of the metallic element as the first work piece (102, 202, 402, 806); depositing a first weld layer (106, 216, 410, 820) on a second end of the base opposite the first end; depositing a second weld layer (108, 300, 412, 822) between the first weld layer (106, 216, 410, 820) and a second end (112, 214) of a second work piece (104, 204, 404) to couple the first work piece (102, 202, 402, 806) to the second work piece (104, 204, 404), the second work piece having a second content of the metallic element higher than the first content, the first weld layer (106, 216, 410, 820) having a third content of the metallic element higher than the first content and lower than the second content, and the second weld layer (108, 300, 412, 822) having a fourth content of the metallic element higher than the third content and lower than the second content; and before the deposition of the second weld layer (108, 300, 412, 822), depositing a third weld layer on the first weld layer (106, 216, 410, 820), the second weld layer (108, 300, 412, 822) to be deposited between the third weld layer and the second end (112, 214) of the second work piece (104, 204, 404), the third weld layer having a fifth content of the metallic element higher than the third content and lower than the fourth content. welding a first end of a base to a first end (110, 212) of a first work piece (102, 202, 402, 806) having a first content of a metallic element, the base having a same content of the metallic element as the first work piece (102, 202, 402, 806); depositing a first weld layer (106, 216, 410, 820) on a second end of the base opposite the first end; depositing a second weld layer (108, 300, 412, 822) between the first weld layer (106, 216, 410, 820) and a second end (112, 214) of a second work piece (104, 204, 404) to couple the first work piece (102, 202, 402, 806) to the second work piece (104, 204, 404), the second work piece having a second content of the metallic element higher than the first content, the first weld layer (106, 216, 410, 820) having a third content of the metallic element higher than the first content and lower than the second content, and the second weld layer (108, 300, 412, 822) having a fourth content of the metallic element higher than the third content and lower than the second content; and before the deposition of the second weld layer (108, 300, 412, 822), depositing a third weld layer on the first weld layer (106, 216, 410, 820), the second weld layer (108, 300, 412, 822) to be deposited between the third weld layer and the second end (112, 214) of the second work piece (104, 204, 404), the third weld layer having a fifth content of the metallic element higher than the third content and lower than the fourth content.
A shape measuring machine for measuring a contour shape of a surface of a to-be-measured object, and surface roughness, comprising: an arm configured to rotate with a support unit as a fulcrum; and a stylus configured to be brought into contact with the to-be-measured object, be displaced up and down following a surface shape of the to-be-measured object, and be mounted at one end of the arm, characterized in that the arm includes a displacement sensor and a scale detector to detect displacement of the arm caused by swing, and the stylus is mounted at a first end being the one end of the arm, the displacement sensor and at least part of the scale detector are mounted at a second end being the other end of the arm, the support unit is mounted on the arm to be closer to the second end than the center of the arm, and a ratio of the length between the fulcrum of the arm and a distal end on a side of the first end to the length between the fulcrum and a distal end on a side of the second end is 1: 1 to 6: 1, and comprising a hemispherical calibration jig, of which shape and dimension are known, for calibrating at least one of the displacement sensor and the scale detector.. an arm configured to rotate with a support unit as a fulcrum; and a stylus configured to be brought into contact with the to-be-measured object, be displaced up and down following a surface shape of the to-be-measured object, and be mounted at one end of the arm, characterized in that the arm includes a displacement sensor and a scale detector to detect displacement of the arm caused by swing, and the stylus is mounted at a first end being the one end of the arm, the displacement sensor and at least part of the scale detector are mounted at a second end being the other end of the arm, the support unit is mounted on the arm to be closer to the second end than the center of the arm, and a ratio of the length between the fulcrum of the arm and a distal end on a side of the first end to the length between the fulcrum and a distal end on a side of the second end is 1: 1 to 6: 1, and comprising a hemispherical calibration jig, of which shape and dimension are known, for calibrating at least one of the displacement sensor and the scale detector..
Fastening arrangement for securing a sensor element, in particular a camera, to a fastening element of a motor vehicle, wherein the sensor element is held on a holding element of the fastening element by a force generated by a spring region of a spring element and oriented in one direction, characterised in that wherein the spring element comprises a second spring region, which at least indirectly adjoins the first spring region, extends at an angle or a right angle to the first spring region and is located between the fastening element and the sensor element, and on which the sensor element is supported in a second direction extending at an angle or a right angle to the first direction, wherein the spring element is supported in the second direction on the fastening element via the second spring region, and wherein the second spring region at least indirectly contacts a surface of the fastening element which faces the sensor element and extends at an angle or a right angle to the second direction.
An ultrahigh-strength steel sheet consisting of, by wt%, carbon: 0.4% to 0.7%, manganese (Mn): 12% to 24%, aluminum (Al): 0.01% to 3.0%, silicon (Si): 0.3% or less, phosphorus: 0.03% or less, sulfur: 0.03% or less, nitrogen: 0.04% or less, nickel (Ni): 0.05% to 1.0%, chromium (Cr): 0.05% to 1.0%, tin (Sn): 0.01% to 0.03%, and a balance of iron (Fe) and inevitable impurities, wherein the ultrahigh-strength steel sheet consisting of austenite as a microstructure, wherein the microstructure of the ultrahigh-strength steel sheet comprises grains of austenite in an amount of 70% or greater that have an aspect ratio of 2 or greater in a rolling direction by an effect of work hardening, wherein the steel sheet has a tensile strength of 1300 MPa or greater and a yield strength of 1000 MPa or greater, the parameters being measured according to the description.
Surgical clip, in particular for use as an implant, comprising two clip arms (14, 16) and a resiliently flexible element via which the two clip arms (14, 16) are connected to each other, wherein the two clip arms (14, 16) each have a first free end, these first free ends being held parallel to and in contact with each other with a predetermined closing force by the resiliently flexible element when the clip is in a rest position, wherein the clip arms (14, 16) are held at a second end thereof opposite the free end on the resiliently flexible element and wherein the clip arms (14, 16) have between their first end and second end sections configured to cross each other, characterized in that the clip arms (14, 16) have stop elements (48, 50) configured to complement each other, said stop elements being adapted to be brought in mutual contact when the clip is transferred from the rest position to an application position in which the free ends of the clip arms (14, 16) are spaced apart from each other, wherein the complementary-configured stop elements (48, 50) are arranged in line with a force application plane in which the transfer of the clip from the rest position to the application position is carried out.