mhurhangee/ep-ind-claims huggingface dataset:
A nonwoven membrane comprising biocompatible electrospun nanofibers and microparticles of at least one active agent in pure form entangled between the nanofibers, obtainable by the method comprising the steps of: (a) electrospinning a solution of a biocompatible polymer; and (b) simultaneously pouring a suspension of microparticles of at least one active agent for obtaining an electrospun nonwoven membrane comprising biocompatible electrospun nanofibers and microparticles of at least one active agent entangled between said nanofibers; wherein the active agent has a water solubility lower than 33 mg/mL and is selected from the group consisting of: 7-ethyl-10-hydroxycamptothecin (SN-38), paclitaxel, cisplatin, carboplatin, etoposide, carmustine, melphalan, camptothecin, 5-fluorouracil, methotrexate, erlotinib, gefitinib, sunitinib, vandetanib, dasatinib, lapatinib, nutlin, gemcitabine, docetaxel, bortezomib, valproic acid, vismodegib, cinacalcet, trabectedin, topotecan, ((1S,2S,4R)-4-(4-(( -2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate, olaparib, iniparib, arsenic trioxide, crizotinib, celecoxib, perifosine, rapamycin, temsirolimus, everolimus, curcumin, resveratrol, genistein, quercetin, chloramphenicol, Penicillin G Procaine, fusidic acid, mebendazol, albendazol, Platelet-derived growth factor (PDGF), Human transforming growth factor-beta (TGF-B), Epidermal growth factor, Vascular Endothelial Growth Factor (VEGF), Insulin-like Growth Factor I (IGF-I), Basic fibroblast growth factor (bFGF) and Hepatocyte growth factor. (a) electrospinning a solution of a biocompatible polymer; and (b) simultaneously pouring a suspension of microparticles of at least one active agent for obtaining an electrospun nonwoven membrane comprising biocompatible electrospun nanofibers and microparticles of at least one active agent entangled between said nanofibers;
A method for anatomical object detection in a medical image of a patient, comprising: receiving a medical image of a patient including a target anatomical object; and detecting a pose of the target anatomical object in the medical image in a series of marginal parameter spaces of increasing dimensionality using a respective trained deep neural network for each of the marginal search spaces, wherein the respective trained deep neural network for each of the marginal parameter spaces is trained by sequentially training each of a plurality of hidden layers to reconstruct respective inputs to each hidden layer in an unsupervised pre-training stage, and training the deep neural network to detect the target anatomical object in the respective marginal parameter space based on ground truth training image patches in the respective marginal parameter space in a supervised training stage, and the respective trained deep neural network for each of the marginal parameter spaces is trained in the supervised training stage by adding an output layer for a target output for the respective marginal parameter space and training the plurality of hidden layers and the output layer using back-propagation to minimize an error between detected image patches for the anatomical object and the ground truth training image patches in the respective marginal parameter space. receiving a medical image of a patient including a target anatomical object; and detecting a pose of the target anatomical object in the medical image in a series of marginal parameter spaces of increasing dimensionality using a respective trained deep neural network for each of the marginal search spaces, wherein
Device for cleaning surfaces of objects, in particular of vehicle bodies, having a) a blowing device (58, 64) and an ionizing device, wherein the blowing device (58, 64) can be used to generate a flow of a gaseous fluid that is ionized by the ionizing device and to direct this flow, with an operating volumetric inflow, onto a surface, of the object, which is to be cleaned and where dirt particles are taken up by the fluid; b) a suction device (34, 72) by means of which fluid loaded with dirt particles can be suctioned, with an operating volumetric outflow, from the surface, of the object, which is to be cleaned, wherein c) the blowing device (58, 64) comprises means (64, 70) which are set up to raise and again lower the operating volumetric inflow at short notice and almost instantaneously. a) a blowing device (58, 64) and an ionizing device, wherein the blowing device (58, 64) can be used to generate a flow of a gaseous fluid that is ionized by the ionizing device and to direct this flow, with an operating volumetric inflow, onto a surface, of the object, which is to be cleaned and where dirt particles are taken up by the fluid; b) a suction device (34, 72) by means of which fluid loaded with dirt particles can be suctioned, with an operating volumetric outflow, from the surface, of the object, which is to be cleaned, c) the blowing device (58, 64) comprises means (64, 70) which are set up to raise and again lower the operating volumetric inflow at short notice and almost instantaneously.
An implant for effecting a fusion of an SI joint, the implant including: an elongated base member having a base member longitudinal axis extending parallel to an implant width axis and perpendicular to an implant longitudinal axis; an elongated first side member extending along a first side longitudinal axis; an elongated second side member extending along a second side longitudinal axis wherein the base member, the first side member, and the second side member are connected together and lie in an implant plane defined by the implant width axis and the implant longitudinal axis; an internal support structure; and a plurality of fusion passages (108, 109, 110) defined by the internal support structure in an area between the first side member, second side member, and base member, each fusion passage (108, 109, 110) extending along a thickness axis perpendicular to the implant plane and defining a respective open area through the implant, characterised in that the internal support structure extends in the implant plane from the base member to the first side member and from the base member to the second side member. an elongated base member having a base member longitudinal axis extending parallel to an implant width axis and perpendicular to an implant longitudinal axis; an elongated first side member extending along a first side longitudinal axis; an elongated second side member extending along a second side longitudinal axis wherein the base member, the first side member, and the second side member are connected together and lie in an implant plane defined by the implant width axis and the implant longitudinal axis; an internal support structure; and a plurality of fusion passages (108, 109, 110) defined by the internal support structure in an area between the first side member, second side member, and base member, each fusion passage (108, 109, 110) extending along a thickness axis perpendicular to the implant plane and defining a respective open area through the implant, characterised in that the internal support structure extends in the implant plane from the base member to the first side member and from the base member to the second side member.
A method for a positioning node coupled to a radio access network, RAN, the method comprising: determining first spatial relations between downlink reference signals, DL-RS, and uplink reference signals, UL-RS, used for positioning in a first cell served by a first RAN node, wherein the first cell is a serving cell for a user equipment, UE; determining second spatial relations between DL-RS and UL-RS used for positioning in one or more second cells served by a second RAN node, wherein the second cells are neighbor cells to the first cell; and configuring the UE to transmit UL-RS according to the first and second spatial relations. determining first spatial relations between downlink reference signals, DL-RS, and uplink reference signals, UL-RS, used for positioning in a first cell served by a first RAN node, wherein the first cell is a serving cell for a user equipment, UE; determining second spatial relations between DL-RS and UL-RS used for positioning in one or more second cells served by a second RAN node, wherein the second cells are neighbor cells to the first cell; and configuring the UE to transmit UL-RS according to the first and second spatial relations.
A washing machine comprising: an outer case; an outer tub disposed in the outer case to receive washing water; a rotational tub disposed in the outer tub and selectively rotatable; and a pulsator rotating in the rotational tub to generate forced water current; a tub cover formed on an upper portion of the outer tub to guide the washing water to an inside of the rotational tub when the rotational tub and/or the pulsator rotate; and a motor for transmitting driving force to the rotational tub and/or the pulsator, the washing machine being characterized by further comprising a net(11,21,31,41,51) formed inwardly extending from an inner end of the tub cover.
A method for determining a protection level of a position estimate using only a single epoch of global navigation satellite system (GNSS) measurements, the method comprising: specifying, in advance, a prior probability density P ( x) of a state x; specifying, in advance, a system model h ( x) that relates the state x to observables z of the measurements; quantifying, during operation, quality metrics q associated with the measurements; specifying, in advance, a non-Gaussian residual error probability density model f ( r i | θ, q i) for each observable z i, where r i is a residual error associated with the observable z i and r = z − h x, and fitting model parameters θ determined off-line a priori; defining, during operation, a posterior probability density P ( x | z, q, θ), where P x θ z q ∝ P x ∏ i f z i − h i x θ q i; and í is a natural number being an index to the observables z, estimating, during operation, the state x; and computing, during operation, the protection level by integrating the posterior probability density P ( x | z, q, θ) over the state x. specifying, in advance, a prior probability density P ( x) of a state x; specifying, in advance, a system model h ( x) that relates the state x to observables z of the measurements; quantifying, during operation, quality metrics q associated with the measurements; specifying, in advance, a non-Gaussian residual error probability density model f ( r i | θ, q i) for each observable z i, where r i is a residual error associated with the observable z i and r = z − h x, and fitting model parameters θ determined off-line a priori; defining, during operation, a posterior probability density P ( x | z, q, θ), where P x θ z q ∝ P x ∏ i f z i − h i x θ q i; and í is a natural number being an index to the observables z, estimating, during operation, the state x; and computing, during operation, the protection level by integrating the posterior probability density P ( x | z, q, θ) over the state x.
A compound of Formula I. wherein R 1 is H, -C alkyl, -CHF 2, -CF 3, -CN, -OCH 3, -OCH 2 CH 3, cyclopropyl, OCF 3, or OCHF 2; R 2 is H, F, -CHF 2, -CF 3, -CN, -OCH 3, -OCHF 2, or OCF 3; provided that R 2 may not be H if R 1 is H; A 1 and A 2 are taken together with their attached nitrogen to form a ring selected from the group A 3 is H, -C alkyl, -SO 2 CH(CH 3) 2, -SO 2 CH 3, or wherein said -C alkyl is optionally substituted with one -NH2 group, one or two - OH groups, and may be additionally substituted with up to six fluorine atoms; A 4 is -H, or -CH 3; or A 3 and A 4 may be taken together with their attached nitrogen to form a ring selected from the group consisting of A 5 is -C cycloalkyl, -C alkyl, wherein said -C alkyl and -C( 4 - 6)cycloalkyl are optionally substituted with up to three fluorine atoms; and said -C alkyl is independently optionally substituted with one cyclobutyl, or up to two cyclopropyl groups; and pharmaceutically acceptable salts thereof. R 1 is H, -C alkyl, -CHF 2, -CF 3, -CN, -OCH 3, -OCH 2 CH 3, cyclopropyl, OCF 3, or OCHF 2; R 2 is H, F, -CHF 2, -CF 3, -CN, -OCH 3, -OCHF 2, or OCF 3; provided that R 2 may not be H if R 1 is H; A 1 and A 2 are taken together with their attached nitrogen to form a ring selected from the group A 3 is H, -C alkyl, -SO 2 CH(CH 3) 2, -SO 2 CH 3, or wherein said -C alkyl is optionally substituted with one -NH2 group, one or two - OH groups, and may be additionally substituted with up to six fluorine atoms; A 4 is -H, or -CH 3; or A 3 and A 4 may be taken together with their attached nitrogen to form a ring selected from the group consisting of A 5 is -C cycloalkyl, -C alkyl, wherein said -C alkyl and -C( 4 - 6)cycloalkyl are optionally substituted with up to three fluorine atoms; and said -C alkyl is independently optionally substituted with one cyclobutyl, or up to two cyclopropyl groups;
A VTOL aircraft comprising: a sling system; and a drag reduction system forward of said sling system, said drag reduction system comprising a shield movable relative to an underside of the VTOL aircraft, characterized in that said shield is a generally planar member and said shield is substantially transverse to a VTOL aircraft longitudinal axis to increase a wake of reduced velocity airflow around a volume defined adjacent to the sling system and below the underside of the VTOL aircraft. a sling system; and a drag reduction system forward of said sling system, said drag reduction system comprising a shield movable relative to an underside of the VTOL aircraft, characterized in that said shield is a generally planar member and said shield is substantially transverse to a VTOL aircraft longitudinal axis to increase a wake of reduced velocity airflow around a volume defined adjacent to the sling system and below the underside of the VTOL aircraft.
A continuous belt screen assembly for arranging in a channel defined by opposed side walls (39, 41) containing liquid to be treated, the continuous belt screen assembly including: a base and opposed sides (18, 20); a moving belt screen defining an inlet arranged to allow liquid to flow into the moving belt screen to be screened; and at least one outlet (40, 43) arranged to allow screened liquid to exit from an outside of the movable belt screen; and a flow restrictor wherein the flow restrictor has a body comprising two parts which are mountable to be spaced from each other and extend outwardly from the opposed sides (18, 20) to be mounted downstream of the at least one outlet (40, 43) to cause a damming effect by restricting the liquid flowing past the body out of the at least one outlet (40, 43), the two parts being plates (24, 26) defining a peripheral operative edge which, in use, the liquid flows across, the peripheral operative edge extending from the base in a direction towards one of the sides (18, 20) to define at least a portion of at least one aperture (48, 50) arranged to control a level of the liquid upstream of the body. a base and opposed sides (18, 20); a moving belt screen defining an inlet arranged to allow liquid to flow into the moving belt screen to be screened; and at least one outlet (40, 43) arranged to allow screened liquid to exit from an outside of the movable belt screen; and a flow restrictor wherein the flow restrictor has a body comprising two parts which are mountable to be spaced from each other and extend outwardly from the opposed sides (18, 20) to be mounted downstream of the at least one outlet (40, 43) to cause a damming effect by restricting the liquid flowing past the body out of the at least one outlet (40, 43), the two parts being plates (24, 26) defining a peripheral operative edge which, in use, the liquid flows across, the peripheral operative edge extending from the base in a direction towards one of the sides (18, 20) to define at least a portion of at least one aperture (48, 50) arranged to control a level of the liquid upstream of the body.
Device for indicating existing compressed air within a system which is loaded with compressed air, the system which is loaded with compressed air having a housing and a housing covering, characterized by a through hole within the housing of a component which is loaded with compressed air of the system which is loaded with compressed air, which through hole is configured so as to acoustically indicate, as a throttle point, the existing pressure in the component which is loaded with compressed air, within a predefined pressure range, it being possible for an outlet opening of the through hole to be closed in a pressure-tight manner by way of the housing covering, the through hole having a diameter in the range from 0.2 mm to 2 mm, preferably from 0.8 mm to 1.2 mm, and particularly preferably 1 mm.
The pet waste disposal device comprising a stabilization pillar mounted in a protection frame characterized in that the bottom part of the pillar is fitted with a pheromone reservoir 10, which attracts the animals to the device; the top part of the protection frame is fitted with an absorption pad and then underneath the absorption pad, at the bottom part of the stabilization pillar, a filtration pad, which eliminates disease-carrying germs and decreases the PH of urine; wherein at the bottom of the frame, the permeable openings are located, which are used to drain the filtered urine and the rainwater in the surrounding areas; underneath the filtration pad, a probe is located, which checks the level of filtration pad contamination and signals the need to replace the filtration pad; the pillar is fitted with a frame with a container, in which a poop bag is attached; the bag is placed in a container to make sure that the bag will not tear; the bag is placed on the frame with the container, the opening of the bag being oriented such that the bag itself provides a covering, which ensures that neither rain nor snow can get into the bag; the pillar is also fitted with a supply bin filled with bags and protection gloves; mounted to the pillar is a feature used to fasten the leash to the pillar with a possibility to lock it down; the pillar is equipped with a pet waste scooper, which is attached to the pillar by a fairly long connective wire; in the top part of the pillar, a plate is located, which can be used for advertising or placing information; above the plate, a solar panel is located, which is connected to rechargeable batteries and lighting units used to illuminate the pet waste disposal device and the access road or sidewalk, or background illumination of advertising board or information pictogram.
A yarn detecting system of a spinning machine wherein the spinning machine has a plurality of ring plates, the yarn detecting system including: a yarn detecting unit provided in the ring plate, wherein the yarn detecting unit includes a yarn detecting device having a sensor provided for each spindle and a determining device determining a state of yarn based on a signal generated by the yarn detecting device; characterized in that the yarn detecting system further includes: a main control device, wherein the signal is transmitted by the determining device to the main control device by wireless communication; and a non-contact power transmission device provided in each ring plate, wherein non-contact electric power transmission is performed between any two adjacent ring plates, wherein electric power is supplied to the yarn detecting unit through the non-contact power transmission device. a yarn detecting unit provided in the ring plate, wherein the yarn detecting unit includes a yarn detecting device having a sensor provided for each spindle and a determining device determining a state of yarn based on a signal generated by the yarn detecting device; characterized in that the yarn detecting system further includes: a main control device, wherein the signal is transmitted by the determining device to the main control device by wireless communication; and a non-contact power transmission device provided in each ring plate, wherein non-contact electric power transmission is performed between any two adjacent ring plates, wherein electric power is supplied to the yarn detecting unit through the non-contact power transmission device. a main control device, wherein the signal is transmitted by the determining device to the main control device by wireless communication; and a non-contact power transmission device provided in each ring plate, wherein non-contact electric power transmission is performed between any two adjacent ring plates, wherein electric power is supplied to the yarn detecting unit through the non-contact power transmission device.
A method for the detection of an analyte in a liquid sample using an open lateral flow assay device including at least one sample addition zone, at least one reaction zone, and at least one sink on a substrate, said zones forming a flow path for said sample on said substrate; a first capture molecule on said assay device, capable of binding to said analyte; and a second capture molecule also capable of binding to said analyte, wherein said first capture molecule carries a first label which is not a magnetic label, thereby forming a detection conjugate, and said second capture molecule is attached to a magnetic particle, thereby forming a capture conjugate, wherein the flow path includes micro-pillars being projections substantially vertical in relation to a surface, and having a height, diameter and reciprocal spacing capable of creating capillary lateral flow of the sample in said flow path, and further wherein a magnetic force is applied to the open side of the flow path, concentrating the detection conjugate to the liquid/air interface.
A safety system for bypass tunnels and the like, characterized in that it comprises: - measurement means for measuring the degree of opening of fire doors arranged between a pressurized chamber and a tunnel; - fan means arranged in said pressurized chamber and adapted to create a pressurized atmosphere with an overpressure with respect to the atmospheric pressure present in said tunnel, said fan means being configured so as to operate as a function of the calculated differential pressure between the pressure in said pressurized chamber and in said tunnel and the measurement performed by said measurement means; - electronic control and management means functionally connected to said measurement means and to said fan means in order to adjust the operating speed of said fan means; - door-closing means applied to said fire doors; - means for the assisted opening and closing of said fire doors, configured so as to aid the opening and the closing of said fire doors following actuation of a panic bar of said fire doors. - measurement means for measuring the degree of opening of fire doors arranged between a pressurized chamber and a tunnel; - fan means arranged in said pressurized chamber and adapted to create a pressurized atmosphere with an overpressure with respect to the atmospheric pressure present in said tunnel, said fan means being configured so as to operate as a function of the calculated differential pressure between the pressure in said pressurized chamber and in said tunnel and the measurement performed by said measurement means; - electronic control and management means functionally connected to said measurement means and to said fan means in order to adjust the operating speed of said fan means; - door-closing means applied to said fire doors; - means for the assisted opening and closing of said fire doors, configured so as to aid the opening and the closing of said fire doors following actuation of a panic bar of said fire doors.