A cyclic chromatographic purification method for the isolation of a product from a feed mixture consisting of the product and at least one further component representing impurities, which impurities bind stronger to the chromatographic stationary phase than the product, the method using at least two chromatographic non-affinity adsorbers as chromatographic stationary phase, grouped into only one first adsorber section and one second adsorber section, wherein if an adsorber section comprises more than one chromatographic adsorber these are permanently connected in series, wherein the first adsorber section has a first adsorber section inlet and a first adsorber section outlet, and the second adsorber section has a second adsorber section inlet and a second adsorber section outlet, the method comprising the following steps in order: a. a first interconnected step (IC1a), wherein the first adsorber section outlet is connected to the second adsorber section inlet during an first interconnected timespan (t ICa), wherein the first adsorber section is loaded via the first adsorber section inlet with feed mixture and wherein product is collected from the second adsorber section outlet; b. a second interconnected step (IC1b), wherein the first adsorber section outlet is connected to the second adsorber section inlet during a second interconnected timespan (t ICb), wherein the first adsorber section is loaded via the first adsorber section inlet with a first washing buffer to transfer product unbound in the first absorber section into the second adsorber section and wherein the stream exiting the first adsorber section outlet is either diluted inline before entering the second adsorber section inlet or is supplemented with feed mixture and wherein product is collected from the second adsorber section outlet; c. a first batch step, wherein during a batch timespan (t B) said first and second adsorber sections (1,2) are disconnected and wherein the first adsorber section is cleaned and regenerated to remove impurities and the first adsorber section outlet is directed to waste and wherein the second adsorber section inlet is either loaded with a second washing buffer or loaded with feed mixture and product is collected from the second adsorber section outlet; d. a third interconnected step (IC2a), wherein the first adsorber section performs tasks of the second adsorber section in the first interconnected step, and the second adsorber section performs tasks of the first adsorber section in the first interconnected step; e. a fourth interconnected step (IC2b), wherein the first adsorber section performs tasks of the second adsorber section in the second interconnected step, and the second adsorber section performs tasks of the first adsorber section in the second interconnected step; f. a second batch step, wherein the first adsorber section performs tasks of the second adsorber section in the first batch step, and the second adsorber section performs tasks of the first adsorber section in the first batch step. a. a first interconnected step (IC1a), wherein the first adsorber section outlet is connected to the second adsorber section inlet during an first interconnected timespan (t ICa), wherein the first adsorber section is loaded via the first adsorber section inlet with feed mixture and wherein product is collected from the second adsorber section outlet; b. a second interconnected step (IC1b), wherein the first adsorber section outlet is connected to the second adsorber section inlet during a second interconnected timespan (t ICb), wherein the first adsorber section is loaded via the first adsorber section inlet with a first washing buffer to transfer product unbound in the first absorber section into the second adsorber section and wherein the stream exiting the first adsorber section outlet is either diluted inline before entering the second adsorber section inlet or is supplemented with feed mixture and wherein product is collected from the second adsorber section outlet; either diluted inline before entering the second adsorber section inlet or is supplemented with feed mixture c. a first batch step, wherein during a batch timespan (t B) said first and second adsorber sections (1,2) are disconnected and wherein the first adsorber section is cleaned and regenerated to remove impurities and the first adsorber section outlet is directed to waste and wherein the second adsorber section inlet is either loaded with a second washing buffer or loaded with feed mixture and product is collected from the second adsorber section outlet; either loaded with a second washing buffer or loaded with feed mixture d. a third interconnected step (IC2a), wherein the first adsorber section performs tasks of the second adsorber section in the first interconnected step, and the second adsorber section performs tasks of the first adsorber section in the first interconnected step; e. a fourth interconnected step (IC2b), wherein the first adsorber section performs tasks of the second adsorber section in the second interconnected step, and the second adsorber section performs tasks of the first adsorber section in the second interconnected step; f. a second batch step, wherein the first adsorber section performs tasks of the second adsorber section in the first batch step, and the second adsorber section performs tasks of the first adsorber section in the first batch step.