A compound of Formula I: wherein R 1 is a 5 or 6 membered aryl, heteroaryl or heterocyclic group wherein each heteroaryl or heterocyclic group contains from 1 to 3 heteroatoms independently selected from the group consisting of nitrogen, oxygen and sulfur; and wherein the aryl, heteroaryl or heterocyclic group is optionally substituted with 1 or 2 groups independently selected from the group consisting of -C 1 -C 6 alkyl, -C 3 -C 6 cycloalkyl, C 1 -C 6 alkylC 3 -C 6 cycloalkyl, halogen, -C 1 -C 6 haloalkyl, -OC 1 -C 6 alkyl, -OC 1 -C 6 haloalkyl, and -C C 1 -C 6 alkyl; R 2 and R 2' are at each occurrence independently H or -C 1 -C 6 alkyl; or one set of R 2 and R 2' combine with the carbon atom to which they are both attached to form a C 3 -C 6 cycloalkyl group; R 3 is H, -C 1 -C 6 alkyl or C 3 -C 6 cycloalkyl, R 4 is H, -C 1 -C 6 alkyl, -OC 1 -C 6 alkyl, -OC 1 -C 6 haloalkyl, -C 3 -C 6 cycloalkyl, or halo; R 5 is a 5 or 6 membered aryl, heteroaryl or heterocyclic group optionally substituted with one, two or three groups independently selected from the group consisting of -C 1 -C 6 alkyl, -C 2 -C 6 alkenyl, -C 2 -C 6 alkynyl, C 3 -C 6 cycloalkyl, C 1 -C 6 alkylC 3 -C 6 cycloalkyl, -C 1 -C 6 haloalkyl, -OC 1 -C 6 alkyl, -OC 1 -C 6 haloalkyl, -O-aryl, and halo; wherein the cycloalkyl group is optionally substituted with -C 1 -C 6 alkyl or -C 1 -C 6 haloalkyl; and wherein the substituent -O-aryl group is optionally substituted with -C 1 -C 6 alkyl, halo, C 1 -C 6 haloalkyl, -OC 1 -C 6 alkyl, or -OC 1 -C 6 haloalkyl; and wherein two substituents on the aryl, heteroaryl, or heterocyclic ring of R 5 optionally combine to form a 8-12 membered bicyclic ring optionally containing one or two oxygen atoms; and wherein the bicyclic ring is optionally substituted with 1 or 2 groups independently selected from the group consisting of -C 1 -C 6 alkyl, -C 1 -C 6 haloalkyl, -OC 1 -C 6 alkyl, -OC 1 -C 6 haloalkyl, -C 3 -C 6 cycloalkyl, and halo; R 6 is H, -C 1 -C 6 alkyl, -C 1 -C 6 haloalkyl, -OC 1 -C 6 alkyl, -OC 1 -C 6 haloalkyl, or halo; or R 6 combines with the aryl, heteroaryl or heterocyclic ring of R 5 to form a tetracyclic ring optionally substituted with 1 or 2 groups independently selected from C 1 -C 6 alkyl, -C 1 -C 6 haloalkyl, -OC 1 -C 6 alkyl, -OC 1 -C 6 haloalkyl, -C 3 -C 6 cycloalkyl, and halo; R 7 is H, -C 1 -C 6 alkyl, -C 1 -C 6 haloalkyl, -OC 1 -C 6 alkyl, -C 1 -C 6 haloalkyl, or halo; n = 1 - 4; or a pharmaceutically acceptable salt thereof. R 1 is a 5 or 6 membered aryl, heteroaryl or heterocyclic group wherein each heteroaryl or heterocyclic group contains from 1 to 3 heteroatoms independently selected from the group consisting of nitrogen, oxygen and sulfur; and wherein the aryl, heteroaryl or heterocyclic group is optionally substituted with 1 or 2 groups independently selected from the group consisting of -C 1 -C 6 alkyl, -C 3 -C 6 cycloalkyl, C 1 -C 6 alkylC 3 -C 6 cycloalkyl, halogen, -C 1 -C 6 haloalkyl, -OC 1 -C 6 alkyl, -OC 1 -C 6 haloalkyl, and -C C 1 -C 6 alkyl; R 2 and R 2' are at each occurrence independently H or -C 1 -C 6 alkyl; or one set of R 2 and R 2' combine with the carbon atom to which they are both attached to form a C 3 -C 6 cycloalkyl group; R 3 is H, -C 1 -C 6 alkyl or C 3 -C 6 cycloalkyl, R 4 is H, -C 1 -C 6 alkyl, -OC 1 -C 6 alkyl, -OC 1 -C 6 haloalkyl, -C 3 -C 6 cycloalkyl, or halo; R 5 is a 5 or 6 membered aryl, heteroaryl or heterocyclic group optionally substituted with one, two or three groups independently selected from the group consisting of -C 1 -C 6 alkyl, -C 2 -C 6 alkenyl, -C 2 -C 6 alkynyl, C 3 -C 6 cycloalkyl, C 1 -C 6 alkylC 3 -C 6 cycloalkyl, -C 1 -C 6 haloalkyl, -OC 1 -C 6 alkyl, -OC 1 -C 6 haloalkyl, -O-aryl, and halo; wherein the cycloalkyl group is optionally substituted with -C 1 -C 6 alkyl or -C 1 -C 6 haloalkyl; and wherein the substituent -O-aryl group is optionally substituted with -C 1 -C 6 alkyl, halo, C 1 -C 6 haloalkyl, -OC 1 -C 6 alkyl, or -OC 1 -C 6 haloalkyl; and wherein two substituents on the aryl, heteroaryl, or heterocyclic ring of R 5 optionally combine to form a 8-12 membered bicyclic ring optionally containing one or two oxygen atoms; and wherein the bicyclic ring is optionally substituted with 1 or 2 groups independently selected from the group consisting of -C 1 -C 6 alkyl, -C 1 -C 6 haloalkyl, -OC 1 -C 6 alkyl, -OC 1 -C 6 haloalkyl, -C 3 -C 6 cycloalkyl, and halo; R 6 is H, -C 1 -C 6 alkyl, -C 1 -C 6 haloalkyl, -OC 1 -C 6 alkyl, -OC 1 -C 6 haloalkyl, or halo; or R 6 combines with the aryl, heteroaryl or heterocyclic ring of R 5 to form a tetracyclic ring optionally substituted with 1 or 2 groups independently selected from C 1 -C 6 alkyl, -C 1 -C 6 haloalkyl, -OC 1 -C 6 alkyl, -OC 1 -C 6 haloalkyl, -C 3 -C 6 cycloalkyl, and halo; R 7 is H, -C 1 -C 6 alkyl, -C 1 -C 6 haloalkyl, -OC 1 -C 6 alkyl, -C 1 -C 6 haloalkyl, or halo; n = 1 - 4; or a pharmaceutically acceptable salt thereof.