mhurhangee/ep-ind-claims huggingface dataset:
A process for the preparation of [3-[[(2R,3S)-2-[ -1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-phosphonic acid bis(phenylmethyl) ester (fosaprepitant dibenzyl ester) of formula II, comprising the steps of, (a) obtaining a solution of fosaprepitant dibenzyl ester of formula II in at least one solvent or a mixture of solvents thereof, (b) adding an inorganic acid to the solution obtained in step (a), wherein the inorganic acid is boric acid, (c) concentrating the reaction mass obtained in step (b), (d) adding at least one solvent or a mixture of solvents thereof to the reaction mass obtained in step (c), (e) filtering the reaction mass obtained in step (d) to obtain a residue, Residue-A, (f) adding at least one solvent or a mixture of solvents thereof to the residue obtained in step (e), (g) filtering the reaction mass obtained in step (f) to obtain a residue, Residue-B, (h) adding at least one solvent or a mixture of solvents thereof to the residue obtained in step (g), (i) filtering the reaction mass obtained in step (h), (j) concentrating the filtrate obtained in step (i) to yield fosaprepitant dibenzyl ester of purity > 96 %. (a) obtaining a solution of fosaprepitant dibenzyl ester of formula II in at least one solvent or a mixture of solvents thereof, (b) adding an inorganic acid to the solution obtained in step (a), wherein the inorganic acid is boric acid, (c) concentrating the reaction mass obtained in step (b), (d) adding at least one solvent or a mixture of solvents thereof to the reaction mass obtained in step (c), (e) filtering the reaction mass obtained in step (d) to obtain a residue, Residue-A, (f) adding at least one solvent or a mixture of solvents thereof to the residue obtained in step (e), (g) filtering the reaction mass obtained in step (f) to obtain a residue, Residue-B, (h) adding at least one solvent or a mixture of solvents thereof to the residue obtained in step (g), (i) filtering the reaction mass obtained in step (h), (j) concentrating the filtrate obtained in step (i) to yield fosaprepitant dibenzyl ester of purity > 96 %.
A 7,8-dihydro-[1 H or 2 H]-imidazo[1,2- a]pyrazolo[4,3- e]pyrimidin-4(5 H)-one or 7,8,9-trihydro-[1 H or 2 H]-pyrimido [1,2- a]pyrazolo[4,3- e]pyrimidin-4(5 H)-one, substituted at the 1 or 2 position with C 2-9 alkyl, C 3-9 cycloalkyl, heteroarylalkyl or arylalkyl in free, or salt form, wherein: alkyl is a saturated or unsaturated hydrocarbon moiety, which may be linear or branched, and may be optionally substituted, with halogen, hydroxy, or carboxy; cycloalkyl is a saturated or unsaturated nonaromatic hydrocarbon moiety, at least some carbon atoms of which form a nonaromatic mono- or bicyclic, or bridged cyclic structure, and which may be optionally substituted with halogen, hydroxy, or carboxy; aryl is a mono or bicyclic aromatic hydrocarbon, optionally substituted, with alkyl, halogen, haloalkyl, hydroxy, carboxy, or an additional aryl or heteroaryl; and heteroaryl is an aromatic moiety wherein one or more of the atoms making up the aromatic ring is sulfur or nitrogen rather than carbon, which may be optionally substituted with alkyl, halogen, haloalkyl, hydroxy or carboxy, with the proviso that said arylalkyl is substituted with alkyl, halogen, haloalkyl, hydroxy, carboxy, or an additional aryl or heteroaryl. alkyl is a saturated or unsaturated hydrocarbon moiety, which may be linear or branched, and may be optionally substituted, with halogen, hydroxy, or carboxy; cycloalkyl is a saturated or unsaturated nonaromatic hydrocarbon moiety, at least some carbon atoms of which form a nonaromatic mono- or bicyclic, or bridged cyclic structure, and which may be optionally substituted with halogen, hydroxy, or carboxy; aryl is a mono or bicyclic aromatic hydrocarbon, optionally substituted, with alkyl, halogen, haloalkyl, hydroxy, carboxy, or an additional aryl or heteroaryl; and heteroaryl is an aromatic moiety wherein one or more of the atoms making up the aromatic ring is sulfur or nitrogen rather than carbon, which may be optionally substituted with alkyl, halogen, haloalkyl, hydroxy or carboxy, with the proviso that said arylalkyl is substituted with alkyl, halogen, haloalkyl, hydroxy, carboxy, or an additional aryl or heteroaryl.
A shirt comprising a collar, wherein the shirt further comprises: a collar stand attached to a shirt body, wherein the collar stand is formed from a self fabric, wherein said collar stand comprises an inner piece and an outer piece, and wherein the inner piece and the outer piece are each formed from the self-fabric fused with a fusible substrate, and wherein the inner piece has substantially the same shape and size as the outer piece, characterized in that the collar stand has stretch and recovery in at least two non-opposing directions thereof, and wherein said collar stand is attached to a substantially rigid portion of said collar, and in that the fusible substrate provides and controls stretch and recovery in two directions, and in that the fusible substrate has greater stretch in one of said two directions. a collar stand attached to a shirt body, wherein the collar stand is formed from a self fabric, wherein said collar stand comprises an inner piece and an outer piece, and wherein the inner piece and the outer piece are each formed from the self-fabric fused with a fusible substrate, and wherein the inner piece has substantially the same shape and size as the outer piece, characterized in that the collar stand has stretch and recovery in at least two non-opposing directions thereof, and wherein said collar stand is attached to a substantially rigid portion of said collar, and in that the fusible substrate provides and controls stretch and recovery in two directions, and in that the fusible substrate has greater stretch in one of said two directions.
An apparatus for collecting urine which consists of a collecting part 60 and a case, whereby the collecting part 60 comprises a total tube 65 constructed as a single body containing an urine absorbing tube 51, a sensor tube 52 and a cleansing tube 53, whereby the collecting part 60 comprises a collecting body 95 where collecting part cases 70 and 70' are freely attachably and detachably fixed to, whereby said total tube 65 is connected to the collecting body 95 having a passage in which the urine absorbing tube 51, the sensor tube 52 and the cleansing tube 53 are continuously running through, whereby the collecting part 60 comprises an absorbing part 61 and a sensor part 62 which are connected to the collecting body 95; whereby said connection between the collecting body 95 and the absorbing part 61 and the sensor part 62 constitutes a joint structure allowing the absorbing part 61 and the sensor part 62 to freely rotate themselves in the direction of gravity, whereby the apparatus further comprises a sensor part 62 which is constructed by one or more sensors capable of recognizing urine.
A method performed by a UE in a Long Term Evolution, LTE, system, comprising: sending a MAC layer signalling to indicate a silence state; sending a layer 1 scheduling request (40, 56, 90, 106, 126) using a pre-allocated uplink transmission resource, wherein the pre-allocated uplink transmission resource is specific to the UE, the layer 1 scheduling request (40, 56, 90, 106, 126) indicating that the UE is requesting to use an uplink resource; resending the layer 1 scheduling request (40, 56, 90, 106, 126) at least one time, using the pre-allocated uplink transmission resource, wherein transmissions occur on the pre-allocated uplink transmission resource only when the UE is sending a layer 1 scheduling request (40, 56, 90, 106, 126) on the pre-allocated uplink transmission resource; sending a Voice over Internet Protocol, VOIP, packet using the uplink resource; wherein the layer 1 scheduling request indicates an end to the silence state. sending a MAC layer signalling to indicate a silence state; sending a layer 1 scheduling request (40, 56, 90, 106, 126) using a pre-allocated uplink transmission resource, wherein the pre-allocated uplink transmission resource is specific to the UE, the layer 1 scheduling request (40, 56, 90, 106, 126) indicating that the UE is requesting to use an uplink resource; resending the layer 1 scheduling request (40, 56, 90, 106, 126) at least one time, using the pre-allocated uplink transmission resource, wherein transmissions occur on the pre-allocated uplink transmission resource only when the UE is sending a layer 1 scheduling request (40, 56, 90, 106, 126) on the pre-allocated uplink transmission resource; sending a Voice over Internet Protocol, VOIP, packet using the uplink resource; wherein the layer 1 scheduling request indicates an end to the silence state.
A method of operating a scheduling entity in a wireless communication network, the method comprising: determining interference tolerance information of a plurality of uplink channels, wherein the interference tolerance information is configured to individually indicate an availability of each of the plurality of uplink channels for grantless uplink data transmission, wherein the interference tolerance information is further configured to indicate two or more levels of different grantless access for each of the plurality of uplink channels and wherein the two or more levels of different grantless access comprise: a first level indicating grantless access not allowed; a second level indicating grantless access allowed with a constraint; and a third level indicating grantless access allowed without constraint. broadcasting the interference tolerance information to one or more subordinate entities; and receiving a grantless uplink data transmission from the one or more subordinate entities utilizing one or more of the plurality of uplink channels according to the interference tolerance information. a first level indicating grantless access not allowed; a second level indicating grantless access allowed with a constraint; and a third level indicating grantless access allowed without constraint. broadcasting the interference tolerance information to one or more subordinate entities; and receiving a grantless uplink data transmission from the one or more subordinate entities utilizing one or more of the plurality of uplink channels according to the interference tolerance information.
Method for detecting an at least partial blockage of a process air channel in a dryer, in which process air is supplied to and/or conveyed away from a drum, which is rotatably mounted as a drying chamber, through the process air channel by means of a process air fan and in which a motor for driving the process air fan is at least switched on and switched off, and/or influenced with respect to its rotational speed, by means of a control device, an evaluation circuit determining the power that is input or output by the motor and detecting an at least partial blockage of the process air channel due to a decrease in power, characterised in that the process air fan, together with the drum, is driven by the motor and in that, for determining the proportion of power allocated to driving the process air fan, either the rotational direction of the motor is modified if the process air fan has a preferred rotational direction with respect to its air conveyance, or the rotational speed of the motor is modified.
Acetabular hip prosthesis consisting of a metallic hemispherical acetabular cup into which an insert is anchored wherein the cup is provided with an arcuate slot forming a longitudinal portion of the hemisphere, contained in a plane perpendicular to the equator to cushion the application of the cup into a previously prepared acetabulum and to remain there in a prestressed state, characterised in that the longitudinal slot of the external cup extends towards the pole at an angle β≤70° measured from the equator and is continued in the shape of a T to its end in both directions in a transverse curved slot forming globally a portion of the latitude of the hemisphere at an angle of 20°<α/2<95°, wherein said transverse slot is terminated at each end by a hole with a diameter of d>4 mm in such a way that, by adjusting the parameters of α and β, the said external cup is provided with a stiffness independent of its size, i.e. constant elasticity, so that the user is always provided with the same resistance to impaction regardless of the diameter of the cup.
A device having a plurality of parallel operating computing units, which is suitable for the error-tolerant execution of digital computer programs by means of the parallel operation of computing units constructed as redundancy units, wherein each computing unit is constructed as a module, and an arbitrary number of computer units can be connected in parallel via data lines for the exchange of data signals, clock lines for forced synchronisation and reset lines for switching off a computer unit, wherein when a computing unit is switched off by means of the reset signals, the computing unit no longer takes part in parallel operation and transitions to a wait setting, wherein each computing unit has a microprocessor control unit (14a, 14b) for controlling the function of the computing unit, for carrying out a data comparison, data exchange and for error processing, and a reset circuit for error-tolerant switching off of an adjacent computing unit, characterised in that the data lines, clock lines and reset lines are cross-strapping connections and in that the computing units have a circuit for generating a unique identifier assigned to the computing unit and a random access memory having an apparatus for error detection and correction.
Tool arrangement comprising a tool receptacle with a clamping mandrel, a rotary tool, placed on the tool receptacle, with a receiving bore and a closed centring ring (6; 8; 11; 17) that is inserted between the clamping mandrel and the rotary tool and has an elastically deformable contour, wherein the centring ring (6; 8; 11; 17) is formed in a circular manner in cross section and has at least one radially outwardly protruding, elastically movable outer centring region (7; 9; 13), characterized in that the outer centring region (7; 9; 13) has a slight oversize compared with the receiving bore and as a result deforms elastically radially inwardly when the rotary tool is fitted.
Positioning device for determining an object depth (12, 14, 16) of a concealed positioning object, in particular of a reinforcing bar, comprising a first positioning sensor, at least one second positioning sensor, and comprising a computation unit, which is provided for determining an object depth (12, 14, 16) at least from a positioning characteristic variable of the first positioning sensor, wherein the first positioning sensor is embodied as an inductive positioning sensor, the second positioning sensor is embodied as a radar sensor, and wherein the computation unit is provided for correcting the determined object depth (12, 14, 16) in at least one operating state by means of a positioning characteristic variable of the second positioning sensor, wherein the second positioning sensor is provided for positioning the positioning object at least substantially independently of a positioning mass of the positioning object, characterized in that the computation unit is provided for determining the object depth (12, 14, 16) by means of at least one object mass information item which describes a positioning mass of the positioning object, wherein the object mass information item is settable by an operator.
A method for checking a circuit devised for contactless data communication, which comprises an antenna and an electronic component coupled with the antenna, comprising the steps of: - generating an alternating magnetic field for the circuit; - exciting the circuit by means of an energy pulse, - capturing an oscillation of the circuit in response to the excitation by the energy pulse; and - evaluating the captured oscillation of the circuit; wherein during the exciting the generating of the alternating magnetic field is effected, and wherein the exciting of the circuit by the energy pulse is effected with the alternating magnetic field constantly present. - generating an alternating magnetic field for the circuit; - exciting the circuit by means of an energy pulse, - capturing an oscillation of the circuit in response to the excitation by the energy pulse; and - evaluating the captured oscillation of the circuit;
Apparatus for presenting structure information about a technical object, having a) an identification module for identifying the technical object, b) a modeling module - to provide a structure model of the identified technical object and - to specifically determine, in each case, an externally recognizable object structure for the technical object and a piece of internal structure information, which is physically associated with the object structure, about the technical object on the basis of the structure model and c) an image generation module (IGEN) - for creating a structure image (SIMG) of the technical object, - for inserting the object structure into the structure image (SIMG) in a manner true to projection and - for inserting the structure information into the structure image (SIMG) in a graphical association with the object structure in a mode of presentation that differs from the mode of presentation of the object structure, d) a projection module for projecting the structure image (SIMG) onto the technical object, and e) a receiver module for receiving sensor data detected by a sensor of the technical object and transmitted by the technical object, wherein the image generation module (IGEN) is set up for inserting the sensor data into the structure image (SIMG) in a graphical association with the object structure. a) an identification module for identifying the technical object, b) a modeling module - to provide a structure model of the identified technical object and - to specifically determine, in each case, an externally recognizable object structure for the technical object and a piece of internal structure information, which is physically associated with the object structure, about the technical object on the basis of the structure model and - to provide a structure model of the identified technical object and - to specifically determine, in each case, an externally recognizable object structure for the technical object and a piece of internal structure information, which is physically associated with the object structure, about the technical object on the basis of the structure model and c) an image generation module (IGEN) - for creating a structure image (SIMG) of the technical object, - for inserting the object structure into the structure image (SIMG) in a manner true to projection and - for inserting the structure information into the structure image (SIMG) in a graphical association with the object structure in a mode of presentation that differs from the mode of presentation of the object structure, - for creating a structure image (SIMG) of the technical object, - for inserting the object structure into the structure image (SIMG) in a manner true to projection and - for inserting the structure information into the structure image (SIMG) in a graphical association with the object structure in a mode of presentation that differs from the mode of presentation of the object structure, d) a projection module for projecting the structure image (SIMG) onto the technical object, and e) a receiver module for receiving sensor data detected by a sensor of the technical object and transmitted by the technical object,
A process for manufacturing a composite pyrotechnic product, comprising at least: - forming the pyrotechnic product by depositing a mixture by three-dimensional printing, said mixture comprising at least: ∘ a binder comprising a polymer polyol cross-linked by a cross-linking agent and having an NCO/OH bridging ratio comprised between 0.2 and 0.6, the binder being free of free cross-linking agent, and ∘ an energetic filler. - forming the pyrotechnic product by depositing a mixture by three-dimensional printing, said mixture comprising at least: ∘ a binder comprising a polymer polyol cross-linked by a cross-linking agent and having an NCO/OH bridging ratio comprised between 0.2 and 0.6, the binder being free of free cross-linking agent, and ∘ an energetic filler. ∘ a binder comprising a polymer polyol cross-linked by a cross-linking agent and having an NCO/OH bridging ratio comprised between 0.2 and 0.6, the binder being free of free cross-linking agent, and ∘ an energetic filler.
Coated part comprising: - a metallic substrate, - a thermal barrier comprising a ceramic material and covering the metallic substrate, characterised in that the coated part further comprises a protective coating covering the thermal barrier, the protective coating comprising, in a first region, a first MAX phase, denoted PZ2, of formula (Zr x Ti 1-x) 2 AlC or a first MAX phase, denoted PC2, of formula (Cr x Ti 1-x) 2 AlC with x non-zero and less than or equal to 1 in the MAX phases PZ2 and PC2, and the protective coating comprising, in a second region covering the first region, a second MAX phase of formula Ti 2 AlC. - a metallic substrate, - a thermal barrier comprising a ceramic material and covering the metallic substrate,
A poxvirus vector comprising nucleic acid encoding: (a) a first HIV envelope (Env) antigen comprising the amino acid sequence of SEQ ID NO: 18; (b) a second HIV Env antigen different from the first HIV Env antigen; (c) a third antigen and a fourth antigen, being two different HIV Gag antigens; and (d) a fifth antigen and a sixth antigen, being two different HIV Pol antigens. (a) a first HIV envelope (Env) antigen comprising the amino acid sequence of SEQ ID NO: 18; (b) a second HIV Env antigen different from the first HIV Env antigen; (c) a third antigen and a fourth antigen, being two different HIV Gag antigens; and (d) a fifth antigen and a sixth antigen, being two different HIV Pol antigens.
A method for fault detection, comprising: actuating a shut off valve to an open position; determining a first air pressure, of air in an enclosed space, at a first time using an air pressure sensor (240;801); determining a second air pressure, of the air in the enclosed space, at a second time using the air pressure sensor (240;801) and in response to actuation of the shut off valve to the open position; characterised by subtracting the first air pressure and the second air pressure to obtain an actual pressure difference; making a transient comparison of the actual pressure difference to a predetermined pressure difference; determining, based on the transient comparison, whether at least one of the shut off valve and a check valve is in a failed state. actuating a shut off valve to an open position; determining a first air pressure, of air in an enclosed space, at a first time using an air pressure sensor (240;801); determining a second air pressure, of the air in the enclosed space, at a second time using the air pressure sensor (240;801) and in response to actuation of the shut off valve to the open position; characterised by subtracting the first air pressure and the second air pressure to obtain an actual pressure difference; making a transient comparison of the actual pressure difference to a predetermined pressure difference; determining, based on the transient comparison, whether at least one of the shut off valve and a check valve is in a failed state.