mhurhangee/ep-ind-claims huggingface dataset:
A foldable multi-stage tricycle, comprising: (a) a front wheel assembly; (b) a mainframe, latched to said front wheel assembly via a front mount; (c) a pair of rear-wheel assemblies; said foldable multi-stage tricycle being characterized in that it further comprises: (d) a pair of folding ring assemblies coupling said rear-wheel assemblies to said mainframe; and (e) a mechanism for simultaneously unlocking said pair of ring assemblies and unlatching said mainframe from said front wheel assembly so that a single pulling motion on said mechanism unlocks and unlatches the foldable tricycle from an assembled state thereof so as to be converted to a folded state thereof. (a) a front wheel assembly; (b) a mainframe, latched to said front wheel assembly via a front mount; (c) a pair of rear-wheel assemblies; (d) a pair of folding ring assemblies coupling said rear-wheel assemblies to said mainframe; and (e) a mechanism for simultaneously unlocking said pair of ring assemblies and unlatching said mainframe from said front wheel assembly so that a single pulling motion on said mechanism unlocks and unlatches the foldable tricycle from an assembled state thereof so as to be converted to a folded state thereof.
A method (500a, 500b) for providing aircraft network communications comprising: checking, by an onboard server of an aircraft, for aircraft network connection readiness; receiving, by the onboard server, a connection request from one or more user devices on the aircraft that subsequently and periodically continue scanning for aircraft network connection readiness; in response to finding, by the onboard server, a secure connection to an aircraft communications network based on one or more connection rules: connecting the onboard server to the aircraft communications network by using one or more long-distance antennas to communicate with one or more ground servers via a satellite communications system or an air-to-ground communications system; notifying the one or more user devices that a network is available; receiving connection approval from the one or more user devices; authenticating the one or more user devices; connecting the one or more user devices to the aircraft network; monitoring network connection status; and in response to determining that the network connection status is insecure based on the one or more connection rules, disconnecting the onboard server from the aircraft communications network. checking, by an onboard server of an aircraft, for aircraft network connection readiness; receiving, by the onboard server, a connection request from one or more user devices on the aircraft that subsequently and periodically continue scanning for aircraft network connection readiness; in response to finding, by the onboard server, a secure connection to an aircraft communications network based on one or more connection rules: connecting the onboard server to the aircraft communications network by using one or more long-distance antennas to communicate with one or more ground servers via a satellite communications system or an air-to-ground communications system; notifying the one or more user devices that a network is available; receiving connection approval from the one or more user devices; authenticating the one or more user devices; connecting the one or more user devices to the aircraft network; monitoring network connection status; and in response to determining that the network connection status is insecure based on the one or more connection rules, disconnecting the onboard server from the aircraft communications network. connecting the onboard server to the aircraft communications network by using one or more long-distance antennas to communicate with one or more ground servers via a satellite communications system or an air-to-ground communications system; notifying the one or more user devices that a network is available; receiving connection approval from the one or more user devices; authenticating the one or more user devices; connecting the one or more user devices to the aircraft network; monitoring network connection status; and in response to determining that the network connection status is insecure based on the one or more connection rules, disconnecting the onboard server from the aircraft communications network.
An implantable tissue repair device comprising: a body comprising a biocompatible hydrogel; and a rigid support at least partly located within the body or device, or connected to the body or device, characterised in that the body further comprises at least one layer of fibres (208, 209) and the device further comprises one or more threads stitched to the fibre layer (208, 209) and to and/or through the support.
A composition comprising one or more blood fraction(s), wherein said fraction(s) are free or substantially free of lipids and lipoproteins and obtained by a method comprising (i) fractionizing blood serum or plasma via ultracentrifugation in a tube into a top fraction, one or more middle fraction(s) and a bottom fraction; and (ii) selecting one or more middle fraction(s), wherein the selected fraction(s) are characterized by being capable of inducing wound healing and/or having a protective effect against oxidative stress and/or reducing inflammatory response and/or decreasing excessive reactive oxygen species activity in a human corneal epithelial cells-transformed (HCE-T) assay, wherein the composition is designed to be administered topically and preferably formulated as drops, ointment or gel. (i) fractionizing blood serum or plasma via ultracentrifugation in a tube into a top fraction, one or more middle fraction(s) and a bottom fraction; and (ii) selecting one or more middle fraction(s), wherein the selected fraction(s) are characterized by being capable of inducing wound healing and/or having a protective effect against oxidative stress and/or reducing inflammatory response and/or decreasing excessive reactive oxygen species activity in a human corneal epithelial cells-transformed (HCE-T) assay,
A suspension formulation comprising a spray dried monoclonal antibody at a concentration of about 200 mg/mL or more suspended in a non-aqueous suspension vehicle, wherein the viscosity of the suspension vehicle is less than about 20 centipoise at about 25°C, and wherein the non-aqueous suspension vehicle comprises ethyl lactate.
A compound of one of the following formulas: formula IIa; or a pharmaceutically acceptable salt, or solvate, thereof; formula IIIa: or a pharmaceutically acceptable salt, or solvate, thereof; formula IVa; or a pharmaceutically acceptable salt, or solvate, thereof; formula IIb: or a pharmaceutically acceptable salt, or solvate, thereof; formula IIIb; or a pharmaceutically acceptable salt, or solvate, thereof; formula IVb: or a pharmaceutically acceptable salt or solvate, thereof, wherein R 1, is selected from hydrogen, halogen, OH, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, OR 7, NH 2, NO 2, NHR 7, NR 7 R 7, S q R 7, C R 7, C OR 7, CF 3, CF 2 H, CFH 2, OCF 3, OCF 2 H, and OCFH 2; R 7 is selected from (a) hydrogen, (b) C 1 -C 6 alkyl, (c) C 2 -C 6 alkenyl, (d) C 2 -C 6 alkynyl, (e) 3-14 membered saturated, partially saturated, or unsaturated carbocycle, and (f) 3-14 membered saturated, partially saturated, or unsaturated heterocycle containing one or more heteroatoms selected from N, O, and S; wherein (b)-(f) optionally is substituted with one or more R 8; R 8 is selected from (a) halogen, (b) OH, (c) NO 2, (c) NH 2, (d) C OH, (e) NH(C 1 -C 6 alkyl), (f) N(C 1 -C 6 alkyl) 2, (g) C O-(C 1 -C 6 alkyl), (h) C 1 -C 6 alkyl, (i) C 1 -C 6 alkoxy, (j) 3-14 membered saturated, partially saturated, or unsaturated carbocycle, (k) 3-14 membered saturated, partially saturated, or unsaturated heterocycle containing one or more heteroatoms selected from N, O, and S; and =O wherein (e)-(k) optionally is substituted with one or more R 9; R 9 is selected from halogen, OH, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C OH, NH 2, NH(C 1 -C 6 alkyl), N(C 1 -C 6 alkyl) 2, NO 2, and S q -(C 1 -C 6 alkyl) and; q is 0, 1, or 2. R 1, is selected from hydrogen, halogen, OH, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, OR 7, NH 2, NO 2, NHR 7, NR 7 R 7, S q R 7, C R 7, C OR 7, CF 3, CF 2 H, CFH 2, OCF 3, OCF 2 H, and OCFH 2; R 7 is selected from (a) hydrogen, (b) C 1 -C 6 alkyl, (c) C 2 -C 6 alkenyl, (d) C 2 -C 6 alkynyl, (e) 3-14 membered saturated, partially saturated, or unsaturated carbocycle, and (f) 3-14 membered saturated, partially saturated, or unsaturated heterocycle containing one or more heteroatoms selected from N, O, and S; wherein (b)-(f) optionally is substituted with one or more R 8; R 8 is selected from (a) halogen, (b) OH, (c) NO 2, (c) NH 2, (d) C OH, (e) NH(C 1 -C 6 alkyl), (f) N(C 1 -C 6 alkyl) 2, (g) C O-(C 1 -C 6 alkyl), (h) C 1 -C 6 alkyl, (i) C 1 -C 6 alkoxy, (j) 3-14 membered saturated, partially saturated, or unsaturated carbocycle, (k) 3-14 membered saturated, partially saturated, or unsaturated heterocycle containing one or more heteroatoms selected from N, O, and S; and =O wherein (e)-(k) optionally is substituted with one or more R 9; R 9 is selected from halogen, OH, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C OH, NH 2, NH(C 1 -C 6 alkyl), N(C 1 -C 6 alkyl) 2, NO 2, and S q -(C 1 -C 6 alkyl) and; q is 0, 1, or 2.
A medical device comprising: an elongate shaft having a proximal end, a distal end, a length and a lumen extending therethrough, the elongate shaft including a plurality of micromachined apertures along at least a portion of the length to facilitate bending; a polymer layer disposed on at least a portion of the elongate shaft, the polymer layer fluidly sealing at least a portion of the plurality of micromachined apertures, a distal portion of the elongate shaft including at least one of the plurality of micromachined apertures being free of the polymer layer, a proximal portion of the elongate shaft including at least one of the plurality of micromachined apertures being free of the polymer layer; an inflatable balloon disposed about at least the distal portion of the elongate shaft being free of the polymer layer, the inflatable balloon in fluid communication with the lumen. an elongate shaft having a proximal end, a distal end, a length and a lumen extending therethrough, the elongate shaft including a plurality of micromachined apertures along at least a portion of the length to facilitate bending; a polymer layer disposed on at least a portion of the elongate shaft, the polymer layer fluidly sealing at least a portion of the plurality of micromachined apertures, a distal portion of the elongate shaft including at least one of the plurality of micromachined apertures being free of the polymer layer, a proximal portion of the elongate shaft including at least one of the plurality of micromachined apertures being free of the polymer layer; an inflatable balloon disposed about at least the distal portion of the elongate shaft being free of the polymer layer, the inflatable balloon in fluid communication with the lumen.
A line monitoring system for an optical communication system comprising: a laser transmitter, said laser transmitter configured for providing an optical output at a carrier wavelength; a code generator configured to generate a test code, said code generator being coupled to said laser transmitter for modulating said test code on said optical output to provide a test signal representative of said test code, said test signal being provided for coupling to an optical path whereby said test signal is returned to the line monitoring system through a first loopback path as a first returned test signal and said test signal is returned to the line monitoring system through a second loopback path as a second returned test signal; and a correlator for simultaneously receiving overlapping portions of said first and second returned test signals (80, 82), characterised in that the line monitoring system further comprises a wavelength dither generator coupled to said laser transmitter, said wavelength dither generator being configured for generating a wavelength dither signal for dithering said carrier wavelength. a laser transmitter, said laser transmitter configured for providing an optical output at a carrier wavelength; a code generator configured to generate a test code, said code generator being coupled to said laser transmitter for modulating said test code on said optical output to provide a test signal representative of said test code, said test signal being provided for coupling to an optical path whereby said test signal is returned to the line monitoring system through a first loopback path as a first returned test signal and said test signal is returned to the line monitoring system through a second loopback path as a second returned test signal; and a correlator for simultaneously receiving overlapping portions of said first and second returned test signals (80, 82), characterised in that the line monitoring system further comprises a wavelength dither generator coupled to said laser transmitter, said wavelength dither generator being configured for generating a wavelength dither signal for dithering said carrier wavelength.
Process for preparing dimeric and/or trimeric silanes of the general formula I where n = 0 or 1, by i) subjecting a reactant stream comprising monosilane of the general formula II and hydrogen, where the reactant stream has a defined ratio of hydrogen and monosilane in per cent by volume (% by vol.) of 15:1 to 1:5, ii) to a gas discharge and iii) obtaining dimeric and/or trimeric silanes of the formula I from the resulting phase, and setting a defined ratio of the partial hydrogen pressure to the partial pressure of the silanes which are gaseous under the conditions selected in the resulting phase by means of a hydrogen-permeable membrane. i) subjecting a reactant stream comprising monosilane of the general formula II and hydrogen, where the reactant stream has a defined ratio of hydrogen and monosilane in per cent by volume (% by vol.) of 15:1 to 1:5, ii) to a gas discharge and iii) obtaining dimeric and/or trimeric silanes of the formula I from the resulting phase, and setting a defined ratio of the partial hydrogen pressure to the partial pressure of the silanes which are gaseous under the conditions selected in the resulting phase by means of a hydrogen-permeable membrane.
A Mach-Zehnder type optical modulator comprising: at least one input waveguide; one output waveguide; a first 3-dB coupler connected to said at least one input waveguide; a second 3-dB coupler connected to said output waveguide; two three-dimensional optical waveguides connecting said first and second 3-dB couplers together, and at least one of said three-dimensional optical waveguides has an electro-optic phase shifter in which at least one electrode is placed; characterized in that the material used for said two three-dimensional optical waveguides is a cubic crystal of KTa 1-x Nb x O 3 with 0<x<1, or K 1-y Li y Ta 1-x Nb x O 3 with 0<x<1 and 0<y<1 having a secondary electro-optic constant, and the optical modulator comprises a temperature controller that controllably adjusts the temperature of said KTa 1-x Nb x O 3 or K 1-y Li y Ta 1-x Nb x O 3 in the vicinity of a phase transition temperature at which said KTa 1-x Nb x O 3 or K 1-y Li y Ta 1-x Nb x O 3 shifts from the cubic crystal to a tetragonal crystal. at least one input waveguide; one output waveguide; a first 3-dB coupler connected to said at least one input waveguide; a second 3-dB coupler connected to said output waveguide; two three-dimensional optical waveguides connecting said first and second 3-dB couplers together, and at least one of said three-dimensional optical waveguides has an electro-optic phase shifter in which at least one electrode is placed; characterized in that the material used for said two three-dimensional optical waveguides is a cubic crystal of KTa 1-x Nb x O 3 with 0<x<1, or K 1-y Li y Ta 1-x Nb x O 3 with 0<x<1 and 0<y<1 having a secondary electro-optic constant, and the optical modulator comprises a temperature controller that controllably adjusts the temperature of said KTa 1-x Nb x O 3 or K 1-y Li y Ta 1-x Nb x O 3 in the vicinity of a phase transition temperature at which said KTa 1-x Nb x O 3 or K 1-y Li y Ta 1-x Nb x O 3 shifts from the cubic crystal to a tetragonal crystal.
Antibody or antigen-binding fragment thereof that binds to the EDA domain of fibronectin-EDA, comprising a heavy chain variable region comprising: - a CDR1 having the amino acid sequence GYSITSGYSWH; - a CDR2 having the amino acid sequence YIHYSGX 1 ANYNPSLKS, and wherein X 1 is selected from S and I; and - a CDR3 having the amino acid sequence EKTGFFDY; and a light chain variable region comprising: - a CDR1 having the amino acid sequence RSSQSLVHSNGNTYLH; - a CDR2 having the amino acid sequence KVSNRFS; and - a CDR3 having the amino acid sequence SQSAHVPPT. - a CDR1 having the amino acid sequence GYSITSGYSWH; - a CDR2 having the amino acid sequence YIHYSGX 1 ANYNPSLKS, and wherein X 1 is selected from S and I; and - a CDR3 having the amino acid sequence EKTGFFDY; - a CDR1 having the amino acid sequence RSSQSLVHSNGNTYLH; - a CDR2 having the amino acid sequence KVSNRFS; and - a CDR3 having the amino acid sequence SQSAHVPPT.
System or autonomous device for providing a direct current to a consumer, and in particular for providing a direct current for the regulated charging of at least one battery, said system or device comprising a combustion engine supplied with a fuel, an alternator and a current-rectifier means suitable for producing a direct current, characterised in that: - said alternator is a synchronous alternator (preferably a triphase alternator) operating at a variable frequency (preferably of the type having permanent magnets, bipolar or multipolar), - said combustion engine is coupled with said alternator, - said current-rectifier means is placed at the output of said alternator and at the input of said consumer, which can be a battery, - said combustion engine and said alternator are dimensioned to provide a power such that the direct current coming from said rectifier means does not exceed a predetermined value, and characterised in that - in said system or device, the direct current demanded by the consumer is self-regulated in such a way that said combustion engine does not receive any outside control signal that can act on its supply of fuel or its speed of rotation, except optionally for the starting of said combustion engine via a starting means, such as an electric starter, and in that - the combustion engine of said system or autonomous device is configured and adjusted to provide a power such that the direct current coming from said rectifier means does not exceed a predetermined value that is less than or equal to the maximum value of the charging current of the battery plus the direct current absorbed by optional other consumers placed in parallel with the battery. - said alternator is a synchronous alternator (preferably a triphase alternator) operating at a variable frequency (preferably of the type having permanent magnets, bipolar or multipolar), - said combustion engine is coupled with said alternator, - said current-rectifier means is placed at the output of said alternator and at the input of said consumer, which can be a battery, - said combustion engine and said alternator are dimensioned to provide a power such that the direct current coming from said rectifier means does not exceed a predetermined value, - in said system or device, the direct current demanded by the consumer is self-regulated in such a way that said combustion engine does not receive any outside control signal that can act on its supply of fuel or its speed of rotation, except optionally for the starting of said combustion engine via a starting means, such as an electric starter, and in that - the combustion engine of said system or autonomous device is configured and adjusted to provide a power such that the direct current coming from said rectifier means does not exceed a predetermined value that is less than or equal to the maximum value of the charging current of the battery plus the direct current absorbed by optional other consumers placed in parallel with the battery.
A pulse generator adapted for use with a lead having a plurality of electrodes, comprising: memory circuitry that stores a first library of pulse shapes and a second library of electrode configurations specifying a polarity and an allocation of current to each of the electrodes; and control circuitry configured to execute a program, wherein the program comprises a first instruction to provide a first number of applications of a first pulse shape from the first library to a first group of the electrodes according to a polarity and allocation of current defined in a first electrode configuration in the second library. memory circuitry that stores a first library of pulse shapes and a second library of electrode configurations specifying a polarity and an allocation of current to each of the electrodes; and control circuitry configured to execute a program, wherein the program comprises a first instruction to provide a first number of applications of a first pulse shape from the first library to a first group of the electrodes according to a polarity and allocation of current defined in a first electrode configuration in the second library.