A thrombectomy catheter system comprising: a catheter (12, 612, 712) including a catheter body (24, 624, 724) and a high pressure tube (28, 628, 728), the catheter body defining an exhaust lumen (30, 30a, 630, 730) and an infusion lumen (32, 32a, 632), and the high pressure tube having a nozzle orifice (40a, 640a, 740a), positioned to direct a fluid jet into a distal opening of the exhaust lumen; a source of infusion fluid communicating with a proximal end of the infusion lumen; a fluid control device fluidly coupled between the catheter and the source of infusion fluid, the fluid control device being adapted to regulate a flow rate of infusion fluid from the source of infusion fluid to the infusion lumen of the catheter, wherein the high pressure tube extends through the infusion lumen of the catheter body; and either 1) a recirculation channel configured to recirculate fluid from the exhaust lumen into a body lumen of a patient and a filter positioned upstream of the recirculation channel; or 2) a) a first recirculation channel configured to recirculate fluid from the exhaust lumen into a body lumen of a patient and a first filter positioned upstream of the first recirculation channel; and/or b) a second recirculation channel configured to recirculate fluid from the exhaust lumen into the high pressure tube and a second filter positioned within the second recirculation channel. a catheter (12, 612, 712) including a catheter body (24, 624, 724) and a high pressure tube (28, 628, 728), the catheter body defining an exhaust lumen (30, 30a, 630, 730) and an infusion lumen (32, 32a, 632), and the high pressure tube having a nozzle orifice (40a, 640a, 740a), positioned to direct a fluid jet into a distal opening of the exhaust lumen; a source of infusion fluid communicating with a proximal end of the infusion lumen; a fluid control device fluidly coupled between the catheter and the source of infusion fluid, the fluid control device being adapted to regulate a flow rate of infusion fluid from the source of infusion fluid to the infusion lumen of the catheter, wherein the high pressure tube extends through the infusion lumen of the catheter body; and either 1) a recirculation channel configured to recirculate fluid from the exhaust lumen into a body lumen of a patient and a filter positioned upstream of the recirculation channel; or 2) a) a first recirculation channel configured to recirculate fluid from the exhaust lumen into a body lumen of a patient and a first filter positioned upstream of the first recirculation channel; and/or b) a second recirculation channel configured to recirculate fluid from the exhaust lumen into the high pressure tube and a second filter positioned within the second recirculation channel. 1) a recirculation channel configured to recirculate fluid from the exhaust lumen into a body lumen of a patient and a filter positioned upstream of the recirculation channel; or 2) a) a first recirculation channel configured to recirculate fluid from the exhaust lumen into a body lumen of a patient and a first filter positioned upstream of the first recirculation channel; and/or b) a second recirculation channel configured to recirculate fluid from the exhaust lumen into the high pressure tube and a second filter positioned within the second recirculation channel. a) a first recirculation channel configured to recirculate fluid from the exhaust lumen into a body lumen of a patient and a first filter positioned upstream of the first recirculation channel; and/or b) a second recirculation channel configured to recirculate fluid from the exhaust lumen into the high pressure tube and a second filter positioned within the second recirculation channel.