A system for providing reduced-pressure therapy and instillation therapy to a tissue site, the system comprising: a dressing comprising: a tissue interface configured to be positioned adjacent the tissue site, and a sealing member configured to cover the tissue interface; a dressing interface fluidly coupled to the dressing; a reduced-pressure therapy system configured to be fluidly coupled to the dressing interface, the reduced-pressure therapy system comprising a reduced-pressure source and a fluid container; and an instillation therapy system configured to be fluidly coupled to the dressing interface, the instillation therapy system comprising: a pressure sensor fluidly coupled to the dressing interface and configured to measure a pressure proximate the tissue site, a valve fluidly coupled to the dressing interface and having an open position configured to permit fluid communication through the valve and a closed position configured to prevent fluid communication through the valve, a canister fluidly coupled to the valve, a flow meter configured to be fluidly coupled between the valve and the dressing interface and determine a rate of fluid flow through the valve, a computing device configured to receive input from the pressure sensor and the flow meter and, in response, operate the valve. a dressing comprising: a tissue interface configured to be positioned adjacent the tissue site, and a sealing member configured to cover the tissue interface; a tissue interface configured to be positioned adjacent the tissue site, and a sealing member configured to cover the tissue interface; a dressing interface fluidly coupled to the dressing; a reduced-pressure therapy system configured to be fluidly coupled to the dressing interface, the reduced-pressure therapy system comprising a reduced-pressure source and a fluid container; and an instillation therapy system configured to be fluidly coupled to the dressing interface, the instillation therapy system comprising: a pressure sensor fluidly coupled to the dressing interface and configured to measure a pressure proximate the tissue site, a valve fluidly coupled to the dressing interface and having an open position configured to permit fluid communication through the valve and a closed position configured to prevent fluid communication through the valve, a canister fluidly coupled to the valve, a flow meter configured to be fluidly coupled between the valve and the dressing interface and determine a rate of fluid flow through the valve, a computing device configured to receive input from the pressure sensor and the flow meter and, in response, operate the valve. a pressure sensor fluidly coupled to the dressing interface and configured to measure a pressure proximate the tissue site, a valve fluidly coupled to the dressing interface and having an open position configured to permit fluid communication through the valve and a closed position configured to prevent fluid communication through the valve, a canister fluidly coupled to the valve, a flow meter configured to be fluidly coupled between the valve and the dressing interface and determine a rate of fluid flow through the valve, a computing device configured to receive input from the pressure sensor and the flow meter and, in response, operate the valve.