mhurhangee/ep-ind-claims huggingface dataset:
A method of preparing a core fucosylated or nonfucosylated IgG antibody or Fc fragment thereof having a predetermined oligosaccharide moiety, the method comprising: providing an IgG antibody or IgG-Fc fragment comprising a core fucosylated or nonfucosylated GlcNAc-acceptor; and enzymatically reacting the core fucosylated or nonfucosylated GlcNAc-acceptor with an activated oligosaccharide donor using a Streptococcus pyogenes Endoglycosidase-S Asp233 mutant, wherein the activated oligosaccharide donor is a synthetic oligosaccharide oxazoline or sialylated oxazoline, wherein the Endoglycosidase-S mutant is selected from a mutant comprising a D233Q site-directed mutation represented by SEQ ID NO: 2 or a D233A site-directed mutation represented by SEQ ID NO: 3, wherein the activated oligosaccharide donor carries an activated oligosaccharide moiety comprising a predetermined number and type of sugar residues, wherein via an enzymatic reaction, the activated oligosaccharide moiety is covalently linked to the core fucosylated or nonfucosylated GlcNAc-acceptor, thereby preparing the fucosylated or nonfucosylated antibody or Fc fragment having the predetermined oligosaccharide moiety. providing an IgG antibody or IgG-Fc fragment comprising a core fucosylated or nonfucosylated GlcNAc-acceptor; and enzymatically reacting the core fucosylated or nonfucosylated GlcNAc-acceptor with an activated oligosaccharide donor using a Streptococcus pyogenes Endoglycosidase-S Asp233 mutant, wherein the activated oligosaccharide donor is a synthetic oligosaccharide oxazoline or sialylated oxazoline, wherein the Endoglycosidase-S mutant is selected from a mutant comprising a D233Q site-directed mutation represented by SEQ ID NO: 2 or a D233A site-directed mutation represented by SEQ ID NO: 3, wherein the activated oligosaccharide donor carries an activated oligosaccharide moiety comprising a predetermined number and type of sugar residues, wherein via an enzymatic reaction, the activated oligosaccharide moiety is covalently linked to the core fucosylated or nonfucosylated GlcNAc-acceptor, thereby preparing the fucosylated or nonfucosylated antibody or Fc fragment having the predetermined oligosaccharide moiety.
Lateral adapter for vehicle seat anchorings, wherein said anchorings are two Isofix type rings, characterized in that it comprises a first bar (1.1) with a length corresponding to at least the separation between two consecutive rings, and some first attachment means (1.2) for attaching the first bar (1.1) to the rings, there being one first attachment means (1.2) for each ring, so as to allow a vehicle seat to be placed at any transverse position on the first bar (1.1).
An apparatus for controlling the flow of urine in a urethra of a patient comprising: an implantable adjustable constriction device for constricting the urethra to influence the flow in the urinary tract; an implantable operation device for operating the constriction device to change the constriction of the urethra; a control device for controlling the operation device, wherein the control device is configured to: control the operation device to constrict the urethra, and control the operation device to release the urethra; and an implantable energy source for supplying energy to the operation device; an internal signal transmitter; wherein the control device is configured to determine the current state of the energy source, and wherein the control device is configured to store measurements related to the current state of the energy source, and wherein the control device is connected to an internal signal transmitter configured to wirelessly transmit information reflecting the current state of the energy source. an implantable adjustable constriction device for constricting the urethra to influence the flow in the urinary tract; an implantable operation device for operating the constriction device to change the constriction of the urethra; a control device for controlling the operation device, wherein the control device is configured to: control the operation device to constrict the urethra, and control the operation device to release the urethra; and an implantable energy source for supplying energy to the operation device; an internal signal transmitter; wherein the control device is configured to determine the current state of the energy source, and wherein the control device is configured to store measurements related to the current state of the energy source, and wherein the control device is connected to an internal signal transmitter configured to wirelessly transmit information reflecting the current state of the energy source.
A temperature controllable textile (2; 5), comprising: two first conductive cloths (21, 23; 51, 53), each having a first metal; and a second conductive cloth (22; 52), having a second metal not identical to the first metal, the second conductive cloth (22; 52) being disposed between the two first conductive cloths (21, 23; 51, 53), the second conductive cloth (22; 52) being in contact with and electrically connected to the two first conductive cloths (21, 23; 51, 53), to form two junction portions; wherein, when a negative end and a positive end of a direct current power (V DC) electrically connect to the two first conductive cloths (21, 23; 51, 53), respectively, the two junction portions form a cooling end and a heating end, respectively. two first conductive cloths (21, 23; 51, 53), each having a first metal; and a second conductive cloth (22; 52), having a second metal not identical to the first metal, the second conductive cloth (22; 52) being disposed between the two first conductive cloths (21, 23; 51, 53), the second conductive cloth (22; 52) being in contact with and electrically connected to the two first conductive cloths (21, 23; 51, 53), to form two junction portions; wherein, when a negative end and a positive end of a direct current power (V DC) electrically connect to the two first conductive cloths (21, 23; 51, 53), respectively, the two junction portions form a cooling end and a heating end, respectively.
A botulinum nanoemulsion composition comprising: a population of nanoparticles, wherein more than 50% of particles have diameters between 10 and 300 nanometers or wherein more than 50% of particles have a range of diameters between 10 and 250 nanometers or wherein more than 50% of particles have a range of diameters between 10 and 200 nanometers or wherein more than 50% of particles have a range of diameters between 10 and 150 nanometers or wherein more than 50% of particles have a range of diameters between 10 and 120 nanometers or wherein more than 50% of particles have a range of diameters between 10 and 100 nanometers or wherein more than 50% of particles have a range of diameters between 10 and 50 nanometers, wherein particles of the nanoemulsion comprise botulinum toxin; an oil; and a surfactant. a population of nanoparticles, wherein more than 50% of particles have diameters between 10 and 300 nanometers or wherein more than 50% of particles have a range of diameters between 10 and 250 nanometers or wherein more than 50% of particles have a range of diameters between 10 and 200 nanometers or wherein more than 50% of particles have a range of diameters between 10 and 150 nanometers or wherein more than 50% of particles have a range of diameters between 10 and 120 nanometers or wherein more than 50% of particles have a range of diameters between 10 and 100 nanometers or wherein more than 50% of particles have a range of diameters between 10 and 50 nanometers, wherein particles of the nanoemulsion comprise botulinum toxin; an oil; and a surfactant.
Apparatus for use in isolating a subject, the apparatus including: a) a door (142; 642); b) a frame (110; 610) movable between collapsed and erected configurations; c) a body (120; 620) supported by the frame (110; 610), wherein in the erected configuration, the body (120; 620) defines an internal volume (130; 630) for containing a subject to thereby substantially isolate the subject from a surrounding environment; and, d) a door actuator (140; 640) supported by the frame (110; 610) and configured to move the door (142; 642) between open and closed positions to thereby provide access to the internal volume (130; 630). a) a door (142; 642); b) a frame (110; 610) movable between collapsed and erected configurations; c) a body (120; 620) supported by the frame (110; 610), wherein in the erected configuration, the body (120; 620) defines an internal volume (130; 630) for containing a subject to thereby substantially isolate the subject from a surrounding environment; and, d) a door actuator (140; 640) supported by the frame (110; 610) and configured to move the door (142; 642) between open and closed positions to thereby provide access to the internal volume (130; 630).
An assembly for frothing a fluid including: - a controllable air source assembly including an air channel having an air inlet and a downstream end; - a fluid channel extending from a fluid inlet to a fluid outlet, the fluid channel including subsequently: ∼ an air inlet emanation point to which the downstream end of the air channel is connected; ∼ a pump; ∼ a fluid restriction; ∼ a heater; ∼ a valve assembly having a first state in which fluid is channeled to the fluid outlet of the fluid channel and a second state in which the fluid is diverted from the fluid channel to a second fluid outlet of the valve assembly; the assembly additionally including: - a water supply channel connected to the fluid channel and including a controllable water valve; - a cleaning reservoir; - a return channel having an upstream end that is connected to the second fluid outlet of the valve assembly and having a downstream end that emanates in the cleaning reservoir; - at least one conductivity sensor that is positioned in the fluid channel; - an electronic controller assembly configured to control at least the pump, the heater, and the valve assembly, wherein the electronic controller assembly is configured to operate the assembly in a production mode and in a cleaning mode; wherein, in the production mode, the fluid inlet of the fluid channel is supplied with fluid to be frothed and wherein, during at least part of the cleaning mode, the fluid inlet of the fluid channel is supplied with cleaning fluid. - a controllable air source assembly including an air channel having an air inlet and a downstream end; - a fluid channel extending from a fluid inlet to a fluid outlet, the fluid channel including subsequently: ∼ an air inlet emanation point to which the downstream end of the air channel is connected; ∼ a pump; ∼ a fluid restriction; ∼ a heater; ∼ a valve assembly having a first state in which fluid is channeled to the fluid outlet of the fluid channel and a second state in which the fluid is diverted from the fluid channel to a second fluid outlet of the valve assembly; ∼ an air inlet emanation point to which the downstream end of the air channel is connected; ∼ a pump; ∼ a fluid restriction; ∼ a heater; ∼ a valve assembly having a first state in which fluid is channeled to the fluid outlet of the fluid channel and a second state in which the fluid is diverted from the fluid channel to a second fluid outlet of the valve assembly; - a water supply channel connected to the fluid channel and including a controllable water valve; - a cleaning reservoir; - a return channel having an upstream end that is connected to the second fluid outlet of the valve assembly and having a downstream end that emanates in the cleaning reservoir; - at least one conductivity sensor that is positioned in the fluid channel; - an electronic controller assembly configured to control at least the pump, the heater, and the valve assembly, wherein the electronic controller assembly is configured to operate the assembly in a production mode and in a cleaning mode;
A timepiece or jewelry part comprising an alloy constituted of at least 750‰ gold by weight, characterized in that the alloy is also constituted of: - at least 200‰ copper, - between 19‰ and 35‰ palladium, - between 1‰ and 16‰ indium, - optionally at least one grain refining element, especially selected from Ru, Ir, Re, Co, V and Mo, - optionally at least one element Y selected from calcium (Ca), strontium (Sr), silicon (Si), titanium (Ti), zirconium (Zr) or magnesium (Mg) - at least 200‰ copper, - between 19‰ and 35‰ palladium, - between 1‰ and 16‰ indium, - optionally at least one grain refining element, especially selected from Ru, Ir, Re, Co, V and Mo, - optionally at least one element Y selected from calcium (Ca), strontium (Sr), silicon (Si), titanium (Ti), zirconium (Zr) or magnesium (Mg)
A device for reducing the sound level of underwater sound sources, with ∘ a sound level-reducing enveloping element, having openings (4, 5) for emitting a gaseous substance, ∘ a central alignment component for the enveloping element, ∘ means for spaced-apart alignment of the enveloping element along the central alignment component, characterised in that ∘ means for spaced-apart alignment of the enveloping element comprise link elements connected together in chain-like manner, suitable for forming a guide which is extensible in concertina-like manner for the sound level-reducing enveloping element. ∘ a sound level-reducing enveloping element, having openings (4, 5) for emitting a gaseous substance, ∘ a central alignment component for the enveloping element, ∘ means for spaced-apart alignment of the enveloping element along the central alignment component, ∘ means for spaced-apart alignment of the enveloping element comprise link elements connected together in chain-like manner, suitable for forming a guide which is extensible in concertina-like manner for the sound level-reducing enveloping element.
Electrical installation device comprising a base device which can be mounted in a commercially available flush-mounted device box and which can be latched to at least one operator control or functional element (2, 3) by means of at least one carrier frame, to which end the at least one operator control or functional element (2, 3) engages with a latching face by means of a latching hook, which is arranged at the end of a spring limb, by a carrier frame recess in the carrier frame, characterized in that a removal protection means is provided which can be mounted on the carrier frame by means of connecting means at the site of the carrier frame recess and which has a frame and a supporting plate which is fastened to the said frame and enters the carrier frame recess and which makes it difficult to deflect the spring limb of the operator control or functional element (2, 3).
An electronic device, the device comprising: a flexible display; a first sensor for detecting whether the electronic device is unfolded; a second sensor for detecting biometric information of a user while the electronic device is being unfolded, and a processor configured to control the electronic device to release a locking state of the electronic device and provide an unlocked screen only if an unfolded angle sensed through the first sensor is greater than or equal to a predetermined first angle and the user is authenticated by the biometric information; and if the user is not authenticated by the biometric information, provide a locked screen. a flexible display; a first sensor for detecting whether the electronic device is unfolded; a second sensor for detecting biometric information of a user while the electronic device is being unfolded, and a processor configured to control the electronic device to release a locking state of the electronic device and provide an unlocked screen only if an unfolded angle sensed through the first sensor is greater than or equal to a predetermined first angle and the user is authenticated by the biometric information; and
A sensor element, comprising a substrate having a strain-sensitive element which is preferably applied by means of thin-film technology and is used for measuring the deformation of the substrate when pressure is applied or a force is introduced, characterised in that the strain-sensitive element consists of XAlO y N 1-y, wherein X is a metal with a high melting temperature in the range of greater than 1400°C and 0 < y < 0.4 applies.
A temperature change composition for providing a cooling sensation to the skin of a user comprising a structured emulsion containing: a phase change material present in an amount between 1% by weight of the temperature change composition and 90% by weight of the temperature change composition; a crystalline initiator present in an amount between 0.1% by weight of the temperature change composition and 30% by weight of the temperature change composition; a carrier present in an amount between 1% by weight of the temperature change composition and 40% by weight of the temperature change composition; and a surfactant present in an amount between 0.5% by weight of the temperature change composition and 15% by weight of the temperature change composition; characterized in that the structured emulsion is a d-phase emulsion. a phase change material present in an amount between 1% by weight of the temperature change composition and 90% by weight of the temperature change composition; a crystalline initiator present in an amount between 0.1% by weight of the temperature change composition and 30% by weight of the temperature change composition; a carrier present in an amount between 1% by weight of the temperature change composition and 40% by weight of the temperature change composition; and a surfactant present in an amount between 0.5% by weight of the temperature change composition and 15% by weight of the temperature change composition; characterized in that the structured emulsion is a d-phase emulsion.
A heat exchanger, comprising partition members respectively separated from each other by a spacing maintained by one of spacing members, the partition members facilitating circulation of two different air flows (4, 5), with total enthalpy heat exchange occurring between said two air flows via said partition members, characterized in that said partition members are made of an air shielding sheet comprising a hydrophilic fiber and having a thickness of 10 to 50 μm and a porosity with an air permeability of 5000sec/100cc or more, and only coated with lithium chloride as a primary constituent, so as to improve moisture permeability, said spacing members are made of a flame resistant corrugated paper having a thickness of 60 to 120 μm, comprising cellulose fibers as a primary constituent, and containing a flame retardant so that the heat exchanger is made to have a flame resistance as a whole by the spacing members; and a migration rate of carbon dioxide gas is not more than 1% in the heat exchanger as a whole. said partition members are made of an air shielding sheet comprising a hydrophilic fiber and having a thickness of 10 to 50 μm and a porosity with an air permeability of 5000sec/100cc or more, and only coated with lithium chloride as a primary constituent, so as to improve moisture permeability, said spacing members are made of a flame resistant corrugated paper having a thickness of 60 to 120 μm, comprising cellulose fibers as a primary constituent, and containing a flame retardant so that the heat exchanger is made to have a flame resistance as a whole by the spacing members; and a migration rate of carbon dioxide gas is not more than 1% in the heat exchanger as a whole.
Extrusion line for producing plastic profiles, preferably plastic pipes, comprising at least an extruder, a tool, a calibration device, as well as further downstream equipment (4, 5), at least the tool featuring at least one aperture, and an extraction device being arranged in front of the tool as viewed in the extrusion direction, by means of which extraction device air in the interior of the plastic profile can be exchanged, the tool consisting of a plurality of functional regions with separate melt channels, by means of which the plastic melt can be divided into part melts and the temperature of the melt can be reduced, characterized in that a chamber is arranged around the extruded pipe downstream from the calibration means, a fan being arranged on the chamber, by means of which air can be guided past the outer wall of the extruded pipe counter to the extrusion direction, the tool comprising at least one shaping nozzle and one shaping mandrel, and the shaping nozzle being divided at the circumference into individual segments, each segment having both a heating device and a cooling device.
A blending device comprising: a blender base; a blending container; and a power source operatively connected to the blending container, configured to supply power to the blending container, and wherein the blending container includes a feature that is powered by the power source; wherein the blending container includes a lid selectively attached thereto; wherein the blending container and the lid include an interlock feature; wherein the blending container includes a wireless controller for communicating with the blender base; characterized in that the blending container is configured to communicate wirelessly with other wireless devices, such as a smartphone, computer, tablet, personal computer, NFC point or other wireless device. a blender base; a blending container; and a power source operatively connected to the blending container, configured to supply power to the blending container, and wherein the blending container includes a feature that is powered by the power source; wherein the blending container includes a lid selectively attached thereto; wherein the blending container and the lid include an interlock feature; wherein the blending container includes a wireless controller for communicating with the blender base; characterized in that the blending container is configured to communicate wirelessly with other wireless devices, such as a smartphone, computer, tablet, personal computer, NFC point or other wireless device.
Vector network analyzer having at least one signal generator which generates a respective RF output signal, and having n measurement ports, where n is an integer greater than or equal to one, each measurement port being assigned an RF coupler and the RF coupler being designed in such a way that the RF coupler couples out an RF signal b n running away from a measurement object in the direction of the respective measurement port (114, 116, 118) from the outside, the at least one signal generator being arranged and designed in such a way that it supplies a respective RF output signal as an outwardly outgoing RF signal at at least one measuring port (114, 116, 118), each RF coupler being assigned a measuring point which measures the respective RF signal b n, each measuring port (114, 116, 118) having precisely one measuring point, wherein for the RF output signal for the at least one signal generator an amplitude and a phase are stored in a parameter field in the VNA in a retrievable manner as a function of at least one parameter, wherein the at least one signal generator is designed in such a way that it reproducibly generates the RF output signal in amplitude and phase as a function of at least this one parameter, wherein the at least one signal generator comprises a phase-locked loop and is coupled to a reference signal, the reference signal being provided such that this signal triggers a reception of the RF signals b n running into the respective measurement port from outside at the corresponding RF coupler. wherein for the RF output signal for the at least one signal generator an amplitude and a phase are stored in a parameter field in the VNA in a retrievable manner as a function of at least one parameter, wherein the at least one signal generator is designed in such a way that it reproducibly generates the RF output signal in amplitude and phase as a function of at least this one parameter, wherein the at least one signal generator comprises a phase-locked loop and is coupled to a reference signal, the reference signal being provided such that this signal triggers a reception of the RF signals b n running into the respective measurement port from outside at the corresponding RF coupler.