mhurhangee/ep-ind-claims huggingface dataset:
A composition comprising temsirolimus or a pharmaceutically acceptable salt thereof at a concentration of 0.01 mg/mL to 2.0 mg/mL, and a pharmaceutically acceptable excipient for use in treating a vascular disease, wherein said composition is administered by direct injection to a disease site in a blood vessel wall or tissue surrounding the blood vessel wall, to deliver a therapeutically effective amount of temsirolimus or a pharmaceutically acceptable salt thereof of 0.005 mg to 5 mg per cm of longitudinal length of the disease site in the blood vessel.
A thermal sensor, comprising: a semiconductor substrate; a first layered film (20, 21, 22) that is provided above the semiconductor substrate and includes a plurality of insulating films; a detection part (3, 37) that is provided on the first layered film (20, 21, 22) and has a heating resistor; a circuit part that is provided on the semiconductor substrate and has a control circuit (16, 17, 18, 19) for controlling the heating resistor; a second layered film (25, 26, 27) that is provided on the heating resistor and above the control circuit (16, 17, 18, 19), and includes a plurality of insulating films; an intermediate layer provided on the second layered film (25, 26, 27); a wiring layer (28, 31) for connecting the heating resistor and the control circuit (16, 17, 18, 19); an electrode for connecting the control circuit (16, 17, 18, 19) with the outside of the thermal sensor, formed on the wiring layer (28, 31); and a third layered film (32, 33) that is provided in a region on the intermediate layer from which a portion above the detection part is excluded and over the wiring layer (28, 31), above the control circuit (16, 17, 18, 19), and that includes a plurality of insulating films; wherein the intermediate layer is made up of any one of aluminum nitride, aluminum oxide, silicon carbide, titanium nitride, tungsten nitride, and titanium tungsten. a semiconductor substrate; a first layered film (20, 21, 22) that is provided above the semiconductor substrate and includes a plurality of insulating films; a detection part (3, 37) that is provided on the first layered film (20, 21, 22) and has a heating resistor; a circuit part that is provided on the semiconductor substrate and has a control circuit (16, 17, 18, 19) for controlling the heating resistor; a second layered film (25, 26, 27) that is provided on the heating resistor and above the control circuit (16, 17, 18, 19), and includes a plurality of insulating films; an intermediate layer provided on the second layered film (25, 26, 27); a wiring layer (28, 31) for connecting the heating resistor and the control circuit (16, 17, 18, 19); an electrode for connecting the control circuit (16, 17, 18, 19) with the outside of the thermal sensor, formed on the wiring layer (28, 31); and a third layered film (32, 33) that is provided in a region on the intermediate layer from which a portion above the detection part is excluded and over the wiring layer (28, 31), above the control circuit (16, 17, 18, 19), and that includes a plurality of insulating films; wherein the intermediate layer is made up of any one of aluminum nitride, aluminum oxide, silicon carbide, titanium nitride, tungsten nitride, and titanium tungsten.
A pouch comprising: a bag body including an accommodation space that can accommodate contents, a first aperture for opening the accommodation space, and a second aperture formed so as not to face the first aperture, for opening the accommodation space; a zipper attached to the bag body, for unsealing and sealing the first aperture, the zipper including a male part and a female part; and a closing sheet attached to the bag body so as to separate the male part and the female part of the zipper from the accommodation space, characterized in that the closing sheet includes a weakened part that can be broken when unsealing of the zipper, and in that the weakened part is a notch formed on a surface facing the zipper, and formed so as not to penetrate through the closing sheet, wherein the zipper further includes a male sheet in which the male part is formed and a female sheet in which the female part is formed, the closing sheet includes a first closing sheet part extending from the male sheet toward the accommodation space and a second closing sheet part extending from the female sheet toward the accommodation space and connected to the first closing sheet part, and the male sheet, the first closing sheet part, the second closing sheet part, and the female sheet configure a single sheet. a bag body including an accommodation space that can accommodate contents, a first aperture for opening the accommodation space, and a second aperture formed so as not to face the first aperture, for opening the accommodation space; a zipper attached to the bag body, for unsealing and sealing the first aperture, the zipper including a male part and a female part; and a closing sheet attached to the bag body so as to separate the male part and the female part of the zipper from the accommodation space, characterized in that the closing sheet includes a weakened part that can be broken when unsealing of the zipper, and in that the weakened part is a notch formed on a surface facing the zipper, and formed so as not to penetrate through the closing sheet, wherein the zipper further includes a male sheet in which the male part is formed and a female sheet in which the female part is formed, the closing sheet includes a first closing sheet part extending from the male sheet toward the accommodation space and a second closing sheet part extending from the female sheet toward the accommodation space and connected to the first closing sheet part, and the male sheet, the first closing sheet part, the second closing sheet part, and the female sheet configure a single sheet. the zipper further includes a male sheet in which the male part is formed and a female sheet in which the female part is formed, the closing sheet includes a first closing sheet part extending from the male sheet toward the accommodation space and a second closing sheet part extending from the female sheet toward the accommodation space and connected to the first closing sheet part, and the male sheet, the first closing sheet part, the second closing sheet part, and the female sheet configure a single sheet.
An L1CAM inhibitor for use in inhibiting metastatic spread of a cancer in a subject, where it has been determined in a cell of the cancer that the cell (i) overexpresses a serpin, wherein the metastasis inhibited is metastasis to the brain or a bone in the subject.
An RF circuit for providing a radio frequency signal, the circuit comprising: a dual inductor including one winding including an input and an output, another winding 216) including an input and an output; and a capacitive load (244,246); wherein the one winding and the another winding are arranged to provide, between the one winding 214) and the another winding, a selected parasitic capacitance; wherein the outputs of the windings (214, 216)are electrically coupled to the capacitive load (244, 246), characterized in that the one winding and the another winding are spatially arranged so that the selected parasitic capacitance, the capacitive load (244, 246) and the inductance of the dual inductor provide a resonant circuit having an RF resonant frequency. a dual inductor including one winding including an input and an output, another winding 216) including an input and an output; and a capacitive load (244,246); wherein the one winding and the another winding are arranged to provide, between the one winding 214) and the another winding, a selected parasitic capacitance; wherein the outputs of the windings (214, 216)are electrically coupled to the capacitive load (244, 246), characterized in that the one winding and the another winding are spatially arranged so that the selected parasitic capacitance, the capacitive load (244, 246) and the inductance of the dual inductor provide a resonant circuit having an RF resonant frequency.
A multifilament spun and twisted from viscose, having a lint piece number of 2 lint pieces per 1000 metres of length or less, preferably 1 lint piece per 1000 metres or less, in particular 0.6 lint piece per 1000 metres or less and a phosphorus content in relation to the alpha cellulose of 2.8 % or higher, preferably 3 % or higher, in particular 3.2 % or higher as well as of 4.2 % or less, preferably 4 % or less, in particular 3.8 % or less.
A method of processing a signal in a receiving terminal provided with a plurality of antennas, the method comprising: demapping a symbol signal received via the plurality of antennas to a bit signal according to a mapping rule adaptively decided and used in a transmitting terminal; extracting reliability information for the bit signal obtained from the demapping; and re-performing the demapping the symbol signal using the reliability information, characterized in that: the mapping rule is selected from at least one mapping group formed by using a mean bit error value of each of available mapping rules, and the extracting the reliability information and the re-performing demapping are repeated as many as a prescribed count respectively based on the decided mapping rule. demapping a symbol signal received via the plurality of antennas to a bit signal according to a mapping rule adaptively decided and used in a transmitting terminal; extracting reliability information for the bit signal obtained from the demapping; and re-performing the demapping the symbol signal using the reliability information, the mapping rule is selected from at least one mapping group formed by using a mean bit error value of each of available mapping rules, and the extracting the reliability information and the re-performing demapping are repeated as many as a prescribed count respectively based on the decided mapping rule.
A method for wireless communications by a base station, BS, comprising: obtaining a first indication that downlink communications to a first user equipment, UE, potentially interfere with uplink communications by a second UE; dynamically allocating, based on the first indication, a first set of one or more resource blocks, RBs, for the downlink communications to the first UE or for the uplink communications by the second UE, via changing from an allocation of a second set of RBs spanning a first bandwidth to an allocation of the first set of RBs, wherein the first set of RBs is allocated adjacent frequency resources compared to the second set of RBs, and/or allocated a second bandwidth smaller than the first bandwidth; and transmitting a second indication of the first set of RBs to the first UE or a second indication of the first set of RBs to the second UE. obtaining a first indication that downlink communications to a first user equipment, UE, potentially interfere with uplink communications by a second UE; dynamically allocating, based on the first indication, a first set of one or more resource blocks, RBs, for the downlink communications to the first UE or for the uplink communications by the second UE, via changing from an allocation of a second set of RBs spanning a first bandwidth to an allocation of the first set of RBs, wherein the first set of RBs is allocated adjacent frequency resources compared to the second set of RBs, and/or allocated a second bandwidth smaller than the first bandwidth; and transmitting a second indication of the first set of RBs to the first UE or a second indication of the first set of RBs to the second UE.
A laser device for generating an optical wave comprising at least two frequencies, such laser device comprising: - a first element comprising a gain region located between one first end defined by a first mirror and a second end defined by an exit region, - a second mirror, distinct from the first element, and arranged so as to form with the first mirror an optical cavity including the gain region and a gap between the exit region and the second mirror, - means for pumping the gain region so as to generate the optical wave, characterized in that the laser device further comprises: - means for shaping the light intensity of the optical wave arranged for selecting at least two transverse modes of the optical wave, said means for shaping the light intensity comprise at least one mask, each mask being patterned with a surface having a non-uniform absorbance, said surface including at least one absorbing area and at least one transmitting area; and - means for shaping the longitudinal and transversal phase profile of the optical wave and arranged for adjusting the frequency difference between at least two transverse modes of the optical wave, said means for shaping the phase profile comprise at least one photonic crystal and/or diffraction grating located at least at one end of the gain region and patterned in order to shape the transverse phase and the transverse intensity of the optical wave. - a first element comprising a gain region located between one first end defined by a first mirror and a second end defined by an exit region, - a second mirror, distinct from the first element, and arranged so as to form with the first mirror an optical cavity including the gain region and a gap between the exit region and the second mirror, - means for pumping the gain region so as to generate the optical wave, - means for shaping the light intensity of the optical wave arranged for selecting at least two transverse modes of the optical wave, said means for shaping the light intensity comprise at least one mask, each mask being patterned with a surface having a non-uniform absorbance, said surface including at least one absorbing area and at least one transmitting area; and - means for shaping the longitudinal and transversal phase profile of the optical wave and arranged for adjusting the frequency difference between at least two transverse modes of the optical wave, said means for shaping the phase profile comprise at least one photonic crystal and/or diffraction grating located at least at one end of the gain region and patterned in order to shape the transverse phase and the transverse intensity of the optical wave.
An advanced communication controller unit for a distributed communication system having a plurality of communication controller units, at least one being an advanced communication controller unit, each coupled to a communication medium and adapted to communicate using a communication protocol; said advanced communication controller unit comprising a protocol event recording circuit, the protocol event recording circuit having: a monitoring input connected to at least one internal protocol event data transmission path of said advanced communication controller unit, said at least one internal protocol event data transmission path connecting between a protocol engine and a host interface of said advanced communication controller unit, wherein said monitoring input is connected to directly monitor status information of host interface registers; and a debug output connected to a memory device; and the protocol event recording circuit adapted to: filter protocol event data received from said monitoring input depending on at least one configuration parameter; and provide filtered protocol event data to said debug output. a monitoring input connected to at least one internal protocol event data transmission path of said advanced communication controller unit, said at least one internal protocol event data transmission path connecting between a protocol engine and a host interface of said advanced communication controller unit, wherein said monitoring input is connected to directly monitor status information of host interface registers; and a debug output connected to a memory device; and filter protocol event data received from said monitoring input depending on at least one configuration parameter; and provide filtered protocol event data to said debug output.
A vehicle headlamp comprising: at least one light source module comprising a substrate and a light emitting diode mounted on the substrate; a shade for shielding a part of light emitted from a light emitting surface of the light emitting diode; a projection lens through which the light passes; and a shade driving unit (28, 28B) configured to move the shade to a light shielding position in which the part of the light emitted from the light emitting surface is shielded, and to an open position in which the light emitted from the light emitting surface is unshielded; wherein the shade being located adjacent to the light emitting surface at the light shielding position, and a focal point of the projection lens is located on the light emitting surface when the shade is in the open position, and characterised in that the focal point of the projection lens is located at a top portion of a slope surface when the shade is in the light shielding position. at least one light source module comprising a substrate and a light emitting diode mounted on the substrate; a shade for shielding a part of light emitted from a light emitting surface of the light emitting diode; a projection lens through which the light passes; and a shade driving unit (28, 28B) configured to move the shade to a light shielding position in which the part of the light emitted from the light emitting surface is shielded, and to an open position in which the light emitted from the light emitting surface is unshielded; wherein the shade being located adjacent to the light emitting surface at the light shielding position, and a focal point of the projection lens is located on the light emitting surface when the shade is in the open position, and characterised in that the focal point of the projection lens is located at a top portion of a slope surface when the shade is in the light shielding position.
A method for determining whether a subject has a predisposition or a susceptibility to develop a cancer selected from the group consisting of a cutaneous malignant melanoma, a renal cancer, and combinations thereof, comprising determining in a biological sample from the subject if MITF (microphthalmia-associated transcription factor) presents or not a mutation reducing or abolishing the sumoylation of MITF, the presence of said mutation being indicative that the subject has a predisposition or a susceptibility to develop such cancer.
An operating panel device comprising: an operating ring having an operable front surface and a back surface opposite to the front surface; and a display device formed of a display and a cover lens disposed on the upper surface of the display including a first portion located inside the operating ring so as to include an inside center of the operating ring, a second portion located outside the operating ring, and, wherein a display of the first portion changes in conjunction with a rotational operation applied to the operating ring, characterized in that the display device further includes a third portion being an arcuate groove portion formed on cover lens connecting the first portion and the second portion, the display device being disposed such that the third portion faces the back surface of the operating ring. an operating ring having an operable front surface and a back surface opposite to the front surface; and a display device formed of a display and a cover lens disposed on the upper surface of the display including a first portion located inside the operating ring so as to include an inside center of the operating ring, a second portion located outside the operating ring, and, wherein a display of the first portion changes in conjunction with a rotational operation applied to the operating ring, characterized in that the display device further includes a third portion being an arcuate groove portion formed on cover lens connecting the first portion and the second portion, the display device being disposed such that the third portion faces the back surface of the operating ring.
A method for dividing a blister strip, wherein a blister strip, comprising a substrate having a plurality of depressions for drug portions and a cover layer for covering the depressions are provided; a 3D sensor device generates an image of the substrate having the depressions, wherein the image comprises depth information; a control device evaluates the image by means of image analysis, wherein during image analysis evaluation it is determined where the depressions are individually situated and which dimensions the depressions comprise, characterized in that control signals for a separating device having at least one separating means are calculated based on the arrangement and the dimensions of the depressions; and the blister strip is, based on the control signals, divided into a plurality of blister strip parts (15, 15', 16).
A collet adaptor for use in tool forming machinery including a body, the body having forward and rear ends and an axial bore extending through the forward and rear ends, a drawbar disposed within the bore for connection to a collet, a forward end of the drawbar being for connection of the collet and the bore being constructed so that the collet can be inserted into the bore from the front end of the bore for connection with the forward end of the drawbar, a biasing arrangement (41, 42) within the bore acting on the drawbar in a direction tending to shift the drawbar rearwardly within the bore, characterised by the bore being constructed so that the drawbar is insertable into the bore from the rear end of the bore and is retained within the bore after insertion by a retainer that secures the drawbar against release from the bore, an end of the drawbar extending out of the bore at the rear end of the body and the drawbar being displaceable within the bore against the biasing influence of the biasing arrangement (41, 42) by load applied to the drawbar end to shift the drawbar forwardly within the bore.
Date mechanism comprising a date driving wheel, a date actuator intended to cooperate with a date wheel to cause it to advance by one step per day, the date wheel being subject to the action of a jumper in order to determine its angular positions, characterised in that the date mechanism further comprises a fixed spindle and an eccentric which is carried by the date driving wheel; in that the date actuator is arranged to be able to slide and pivot with respect to said fixed spindle; in that the eccentric is arranged to drive the date actuator; and in that the eccentric, the fixed spindle and the date actuator are arranged with respect to the date driving wheel in order that: • the date actuator causes the date wheel to advance by one step when the date driving wheel turns in a first direction but does not cause the date wheel to pivot when the date driving wheel pivots in a second direction opposite to the first; and in order that • the date actuator can slide and pivot with respect to the fixed spindle against the action of an elastic force or deform elastically under the action of the date wheel without driving the date driving wheel, a rotation of the date wheel by an auxiliary mechanism when the date actuator is in the path of the tooth arrangement of the date wheel thus not driving the rotation of the date driving wheel. • the date actuator causes the date wheel to advance by one step when the date driving wheel turns in a first direction but does not cause the date wheel to pivot when the date driving wheel pivots in a second direction opposite to the first; and in order that • the date actuator can slide and pivot with respect to the fixed spindle against the action of an elastic force or deform elastically under the action of the date wheel without driving the date driving wheel, a rotation of the date wheel by an auxiliary mechanism when the date actuator is in the path of the tooth arrangement of the date wheel thus not driving the rotation of the date driving wheel.