mhurhangee/ep-ind-claims huggingface dataset:
A façade system suitable for attaching to a structural substrate comprising:- at least one façade panel comprising a front face and a rear face and an edge member intermediate to and contiguous to the front face and the rear face;- at least one panel support element having a first arm, a second arm and a bridging portion intermediate the first and second arm, wherein the first arm of the at least one panel support element is connected to the rear face of the at least one façade panel;- a support plate; at least one panel retaining means comprising means for attaching the panel retaining means to the support plate and means for securing the at least one panel support element to the at least one panel retaining means; - and spacing means intermediate the panel retaining means and the structural substrate, wherein the spacing means comprises a structural support element and a structural spacer element; characterized in that the means for securing the at least one panel support element comprises a channel formation for retaining the second arm of the at least one panel support element; and in that the support plate is positioned intermediate the panel retaining means and the structural spacer element, wherein the support plate comprises a support surface attached to a support shaft, the panel retaining means being attachable to the support plate and the support shaft being engageable into the structural spacer element so as to allow the height of the support plate to be adjusted to a desired relative distance from the surface of structural substrate. at least one façade panel comprising a front face and a rear face and an edge member intermediate to and contiguous to the front face and the rear face;- at least one panel support element having a first arm, a second arm and a bridging portion intermediate the first and second arm, wherein the first arm of the at least one panel support element is connected to the rear face of the at least one façade panel;- a support plate; at least one panel retaining means comprising means for attaching the panel retaining means to the support plate and means for securing the at least one panel support element to the at least one panel retaining means; - and spacing means intermediate the panel retaining means and the structural substrate, wherein the spacing means comprises a structural support element and a structural spacer element; characterized in that the means for securing the at least one panel support element comprises a channel formation for retaining the second arm of the at least one panel support element; and in that the support plate is positioned intermediate the panel retaining means and the structural spacer element, wherein the support plate comprises a support surface attached to a support shaft, the panel retaining means being attachable to the support plate and the support shaft being engageable into the structural spacer element so as to allow the height of the support plate to be adjusted to a desired relative distance from the surface of structural substrate.
A method for localizing electromagnetic sources in the brain, including performing an EEG procedure (36, 56) on the brain by an EEG system, including measuring electromagnetic potentials and virtually disposing a plurality of first model sources in the brain and obtaining one or more first solutions, corresponding to said first model sources, to an inverse problem relating said first model sources and said measured potentials for localizing real sources of neural activity in the brain corresponding to said first model sources, characterized by: performing a first tractographic analysis (32,52) of one or more first tracts in the brain by a tractographic system, and wherein said one or more first solutions are obtained at least in part by constraining said one or more solutions so as to take account of said first tractographic analysis. performing a first tractographic analysis (32,52) of one or more first tracts in the brain by a tractographic system, and wherein said one or more first solutions are obtained at least in part by constraining said one or more solutions so as to take account of said first tractographic analysis.
An applicator applying a microneedle (Da) to a skin, the applicator comprising: a transmission member transmitting a biasing force of an elastic member to the microneedle (Da); a housing containing at least a part of the transmission member and guiding a reciprocation of the transmission member; and a cap disposed so as to cover the housing and adapted to impart the biasing force to the elastic member by being pressed toward the transmission member; wherein the transmission member is provided with a stopper extending in a direction orthogonal to an axial direction of the transmission member; characterised in that one end of the housing adapted to mount the stopper is formed with a projection guiding the stopper along one circumferential direction, the projection having an inclined part helically inclined along the circumferential direction and a wall part cut along the axial direction of the housing from a top of the inclined part; wherein the inside of the cap is formed with a lead part adapted to come into contact with the stopper when the cap is pushed; and wherein the stopper is slid by the lead part to the top of the projection when the cap is pushed toward the transmission member, by which the transmission member moves toward the cap while rotating, and thereafter disengages from the projection when the cap is further pushed toward the transmission member, so that the transmission member transmits the biasing force to the microneedle (Da). a transmission member transmitting a biasing force of an elastic member to the microneedle (Da); a housing containing at least a part of the transmission member and guiding a reciprocation of the transmission member; and a cap disposed so as to cover the housing and adapted to impart the biasing force to the elastic member by being pressed toward the transmission member; wherein the transmission member is provided with a stopper extending in a direction orthogonal to an axial direction of the transmission member; characterised in that one end of the housing adapted to mount the stopper is formed with a projection guiding the stopper along one circumferential direction, the projection having an inclined part helically inclined along the circumferential direction and a wall part cut along the axial direction of the housing from a top of the inclined part; wherein the inside of the cap is formed with a lead part adapted to come into contact with the stopper when the cap is pushed; and wherein the stopper is slid by the lead part to the top of the projection when the cap is pushed toward the transmission member, by which the transmission member moves toward the cap while rotating, and thereafter disengages from the projection when the cap is further pushed toward the transmission member, so that the transmission member transmits the biasing force to the microneedle (Da).
A method of analysing a target polynucleotide, the method comprising: expanding the target polynucleotide to form an expanded polynucleotide by expanding each nucleotide in the target polynucleotide in order into clock nucleotides and at least one signal nucleotide in a predetermined order, wherein the clock nucleotides have a predetermined sequence common to each nucleotide in the target polynucleotide, and the at least one signal nucleotide is characteristic of the identity of the respective nucleotide in the target polynucleotide; and during translocation of the expanded polynucleotide through a nanopore, making electrical measurements dependent on the expanded polynucleotide within the pore and deriving an analysis signal therefrom. expanding the target polynucleotide to form an expanded polynucleotide by expanding each nucleotide in the target polynucleotide in order into clock nucleotides and at least one signal nucleotide in a predetermined order, wherein the clock nucleotides have a predetermined sequence common to each nucleotide in the target polynucleotide, and the at least one signal nucleotide is characteristic of the identity of the respective nucleotide in the target polynucleotide; and during translocation of the expanded polynucleotide through a nanopore, making electrical measurements dependent on the expanded polynucleotide within the pore and deriving an analysis signal therefrom.
Method for detecting defects (4a, 4b) of fibre material of a fibre composite material placed on a tool for producing a fibre composite component, having the steps of: - determining a height profile of a fibre material surface of a fibre material placed on the tool by means of a height profile determination apparatus and saving the height profile as a digital dataset in an electronic data memory, and characterized in that, by means of an evaluation unit, - the height profile is divided into a plurality of partial regions which correspond to corresponding partial regions on the fibre material surface of the placed fibre material, - a statistical deviation of the height levels of the height profile relating to the respective partial region is determined for each partial region by means of a statistical evaluation and then it is established, in dependence on the determined statistical deviation of the height levels, whether the applicable partial region is a potential defect region (5a, 5b) for which it should be assumed that at least one potential defect (4a, 4b) of the placed fibre material is located in the partial region and, if previously at least one potential defect region (5a, 5b) was established, - property data of the placed fibre material can be respectively determined for each potential defect region (5a, 5b) from a stored database, wherein the property data describe one or more properties of the placed fibre material, and then a defect (4a, 4b) is detected in the potential defect regions (5a, 5b) in dependence on an evaluation of the determined property data. - determining a height profile of a fibre material surface of a fibre material placed on the tool by means of a height profile determination apparatus and saving the height profile as a digital dataset in an electronic data memory, and - the height profile is divided into a plurality of partial regions which correspond to corresponding partial regions on the fibre material surface of the placed fibre material, - a statistical deviation of the height levels of the height profile relating to the respective partial region is determined for each partial region by means of a statistical evaluation and then it is established, in dependence on the determined statistical deviation of the height levels, whether the applicable partial region is a potential defect region (5a, 5b) for which it should be assumed that at least one potential defect (4a, 4b) of the placed fibre material is located in the partial region and, if previously at least one potential defect region (5a, 5b) was established, - property data of the placed fibre material can be respectively determined for each potential defect region (5a, 5b) from a stored database, wherein the property data describe one or more properties of the placed fibre material, and then a defect (4a, 4b) is detected in the potential defect regions (5a, 5b) in dependence on an evaluation of the determined property data.
A film for administration of an active agent to a body surface, the film comprising: (a) a blend of a hydrophilic polymer and a plasticizer, wherein the plasticizer is capable of non-covalent bonding to the hydrophilic polymer; wherein the weight ratio of the hydrophilic polymer to plasticizer is in the range of about 1.5:1 to about 3:1; wherein the plasticizer is a bifunctional, linear oligomer having a functional group at each terminus, each of said terminal functional groups capable of noncovalently bonding to the hydrophilic polymer, and wherein the hydrophilic polymer is selected from poly (N-vinyl lactams), poly (N-vinyl amides), poly (N-vinyl acrylamides), poly (N-alkylacrylamides), poly (N-vinyl acetamides), substituted and unsubstituted acrylic and methacrylic acid polymers, polyvinyl alcohol, polyvinylamine, and copolymers and blends thereof; (b) a rapidly dissolving polymeric material selected from oligosaccharides and polysaccharides; and (c) an effective amount of an active agent, wherein the blend and the rapidly dissolving polymeric material facilitate dissolution of the film within 10 minutes following application of the film to a moist body surface. (a) a blend of a hydrophilic polymer and a plasticizer, wherein the plasticizer is capable of non-covalent bonding to the hydrophilic polymer; wherein the weight ratio of the hydrophilic polymer to plasticizer is in the range of about 1.5:1 to about 3:1; wherein the plasticizer is a bifunctional, linear oligomer having a functional group at each terminus, each of said terminal functional groups capable of noncovalently bonding to the hydrophilic polymer, and wherein the hydrophilic polymer is selected from poly (N-vinyl lactams), poly (N-vinyl amides), poly (N-vinyl acrylamides), poly (N-alkylacrylamides), poly (N-vinyl acetamides), substituted and unsubstituted acrylic and methacrylic acid polymers, polyvinyl alcohol, polyvinylamine, and copolymers and blends thereof; (b) a rapidly dissolving polymeric material selected from oligosaccharides and polysaccharides; and (c) an effective amount of an active agent, wherein the blend and the rapidly dissolving polymeric material facilitate dissolution of the film within 10 minutes following application of the film to a moist body surface.
A coated cutting tool comprising a substrate and a coating layer formed on a surface of the substrate, wherein: the coating layer comprises at least one α-type aluminum oxide layer and a Ti compound layer between the substrate and the α-type aluminum oxide layer, wherein an average thickness of the α-type aluminum oxide layer is from 1.0 μm or more to 15 μm or less; and in the α-type aluminum oxide layer, when regarding a "texture coefficient of a (0,0,6) plane," which is represented by formula below, as being denoted as a "TC18 (0,0,6)," and also regarding a "texture coefficient of a (0,0,12) plane," which is represented by formula below, as being denoted as a "TC18 (0,0,12)," the TC18 (0,0,6) is the highest texture coefficient and the TC18 (0,0,12) is the second highest texture coefficient from among texture coefficients of eighteen crystal planes of the α-type aluminum oxide layer which are set forth below. [Equation 1] TC 18 0 0,6 = I 0 0,6 I 0 0 0,6 1 18 ∑ I h k l I 0 h k l − 1 [Equation 2] TC 18 0,0 12 = I 0,0 12 I 0 0,0 12 1 18 ∑ I h k l I 0 h k l − 1 In formulae and, I (h,k,l) denotes a peak intensity for an (h,k,l) plane in X-ray diffraction of the α-type aluminum oxide layer, I 0 (h,k,l) denotes a standard diffraction intensity for an (h,k,l) plane which is indicated on JCPDS Card No. 10-0173 for α-type aluminum oxide, and (h,k,l) refers to the eighteen crystal planes of (0,1,2), (1,0,4), (1,1,0), (0,0,6), (1,1,3), (2,0,2), (0,2,4), (1,1,6), (0,1,8), (2,1,4), (3,0,0), (1,0,10), (0,2,10), (0,0,12), (0,1,14), (2,0,14), (1,1,15) and (1,0,16). the coating layer comprises at least one α-type aluminum oxide layer and a Ti compound layer between the substrate and the α-type aluminum oxide layer, wherein an average thickness of the α-type aluminum oxide layer is from 1.0 μm or more to 15 μm or less; and in the α-type aluminum oxide layer, when regarding a "texture coefficient of a (0,0,6) plane," which is represented by formula below, as being denoted as a "TC18 (0,0,6)," and also regarding a "texture coefficient of a (0,0,12) plane," which is represented by formula below, as being denoted as a "TC18 (0,0,12)," the TC18 (0,0,6) is the highest texture coefficient and the TC18 (0,0,12) is the second highest texture coefficient from among texture coefficients of eighteen crystal planes of the α-type aluminum oxide layer which are set forth below. [Equation 1] TC 18 0 0,6 = I 0 0,6 I 0 0 0,6 1 18 ∑ I h k l I 0 h k l − 1 [Equation 2] TC 18 0,0 12 = I 0,0 12 I 0 0,0 12 1 18 ∑ I h k l I 0 h k l − 1 In formulae and, I (h,k,l) denotes a peak intensity for an (h,k,l) plane in X-ray diffraction of the α-type aluminum oxide layer, I 0 (h,k,l) denotes a standard diffraction intensity for an (h,k,l) plane which is indicated on JCPDS Card No. 10-0173 for α-type aluminum oxide, and (h,k,l) refers to the eighteen crystal planes of (0,1,2), (1,0,4), (1,1,0), (0,0,6), (1,1,3), (2,0,2), (0,2,4), (1,1,6), (0,1,8), (2,1,4), (3,0,0), (1,0,10), (0,2,10), (0,0,12), (0,1,14), (2,0,14), (1,1,15) and (1,0,16).
Method for forming a protective coating against high-temperature oxidation on a surface of a refractory composite material based on silicon and niobium, characterised in that chromium present on the surface to be protected is reacted with a reactive gas which contains silicon and oxygen in order to produce a composite coating having two phases, the first phase of which is an oxide phase based on silica (SiO 2) which has adjustable viscoplastic properties and the second phase of which is based on silicon, chromium and oxygen (CrSiO), and in that the first phase and second phase are coalesced at high temperature, which allows a protective coating to be formed in which the second phase acts as a reservoir to reform, during operation, the first phase by means of reaction with an oxidising gas.
A particulate matter measurement device comprising a dilutor that is connected to an exhaust pipe of an automobile and connected to a dilution gas introducing inlet (Ia) and that mixes an exhaust gas from an engine of the automobile with a dilution gas so as to dilute the exhaust gas, a mass-related value measurement device into which a part of the diluted exhaust gas diluted by the d'ilutor is introduced and that continuously measures a mass-related value indirectly indicating a mass of particulate matters contained in the diluted exhaust gas, a collection filter through which the remainder of the diluted exhaust gas passes and that collects the particulate matters contained in the remainder of the diluted exhaust gas, a dilution gas flow rate adjusting device that adjusts a flow rate of the dilution gas introduced into the dilutor, a filter passing flow rate adjusting device that adjusts a flow rate of the diluted exhaust gas passing the collection filter, characterized by a control part adapted to keep a flow rate of the diluted exhaust gas passing the collection filter at a constant value by controlling the filter passing flow rate adjusting device and adapted to secure a necessary flow rate of the diluted exhaust gas introduced into the mass-related value measurement device by controlling the dilution gas flow rate adjusting device, and an information processing part adapted to calculate a correlation between a mass measurement value of the particulate matters collected by the collection filter during a predetermined period while the engine is in operation and a time integrated value of the mass-related value measurement data during the predetermined period as being a time series change data of the mass-related value measured by the mass-related value measurement device and adapted to convert the mass-related value measurement data to the time series change data of the mass of the particulate matters based on the correlation.
An image forming system comprising: an image forming apparatus configured to form an image on a recording material; a pressure sealing processing apparatus configured to execute a pressure sealing processing process of pressure-sealing the recording material by folding the recording material on which the image is formed by the image forming apparatus and applying pressure to the folded recording material; and a control unit configured to control the image forming apparatus and the pressure sealing processing apparatus, characterized in that the control unit is configured to permit execution of the pressure sealing processing process by the pressure sealing processing apparatus on a recording material of which a grammage is smaller than a predetermined grammage, and is configured not to permit execution of the pressure sealing processing process by the pressure sealing processing apparatus on a recording material of which a grammage is equal to or more than the predetermined grammage. an image forming apparatus configured to form an image on a recording material; a pressure sealing processing apparatus configured to execute a pressure sealing processing process of pressure-sealing the recording material by folding the recording material on which the image is formed by the image forming apparatus and applying pressure to the folded recording material; and a control unit configured to control the image forming apparatus and the pressure sealing processing apparatus, characterized in that the control unit is configured to permit execution of the pressure sealing processing process by the pressure sealing processing apparatus on a recording material of which a grammage is smaller than a predetermined grammage, and is configured not to permit execution of the pressure sealing processing process by the pressure sealing processing apparatus on a recording material of which a grammage is equal to or more than the predetermined grammage.
A method of diagnosing prostate cancer in a human subject comprising quantitating methylation in genomic DNA obtained from the human subject in at least one target region selected from the group consisting of SEQ ID NO: 18 and SEQ ID NO:39, wherein significant methylation changes indicate the presence of prostate cancer or a prostate cancer field defect, wherein the change is relative to tissue from a second human subject who does not have prostate cancer.