mhurhangee/ep-ind-claims huggingface dataset:
Method for assigning position values, detected by means of a position detection system, to a topographic image of an object or body part, the method comprising the following steps: - providing a topographic model of an object or body part, - scanning a surface of the object or body part by means of a scanning instrument, which has a scanning tip with a partly spherical external surface, - detecting position values during the scanning and - assigning detected position values to corresponding positions in the topographic model, the detected position values being assigned to points of a virtual surface of the topographic model, which has a distance from a model surface which equals a radius of a partly spherical scanning tip of a scanning instrument, by means of which the surface of the object or body part is scanned in each case. - providing a topographic model of an object or body part, - scanning a surface of the object or body part by means of a scanning instrument, which has a scanning tip with a partly spherical external surface, - detecting position values during the scanning and - assigning detected position values to corresponding positions in the topographic model, the detected position values being assigned to points of a virtual surface of the topographic model, which has a distance from a model surface which equals a radius of a partly spherical scanning tip of a scanning instrument, by means of which the surface of the object or body part is scanned in each case.
A computer implemented method for selecting an implant model associated with the lowest risk of a patient developing cardiac conduction abnormalities as a result of transcatheter structural heart intervention, including: - retrieving a patient-specific anatomical model representing a patient-specific cardiac region, said patient-specific anatomical model comprising a finite element mesh; - retrieving a plurality of implant models representing a finite element representation of a cardiac implant, each modeling geometrical and/or material properties of a corresponding implant; - virtually placing each implant model into said patient-specific anatomical model; - determining, from the virtually placed implant model into said patient-specific anatomical model, a measure of mechanical interaction between each implant model and the patient-specific anatomical model; and - determining a measure of risk of the patient developing cardiac conduction abnormalities on the basis of the determined mechanical interaction for each of the implant models, - selecting a cardiac implant corresponding to one of the plurality of the implant models for a percutaneous implantation procedure which minimizes the measured risk, characterised by further including: - estimating a position of the conduction system in the patient-specific anatomical model; and wherein determining the measure of the mechanical interaction includes: - determining the measure of mechanical interaction at or around the estimated location of the conduction system. - retrieving a patient-specific anatomical model representing a patient-specific cardiac region, said patient-specific anatomical model comprising a finite element mesh; - retrieving a plurality of implant models representing a finite element representation of a cardiac implant, each modeling geometrical and/or material properties of a corresponding implant; - virtually placing each implant model into said patient-specific anatomical model; - determining, from the virtually placed implant model into said patient-specific anatomical model, a measure of mechanical interaction between each implant model and the patient-specific anatomical model; and - determining a measure of risk of the patient developing cardiac conduction abnormalities on the basis of the determined mechanical interaction for each of the implant models, - selecting a cardiac implant corresponding to one of the plurality of the implant models for a percutaneous implantation procedure which minimizes the measured risk, - estimating a position of the conduction system in the patient-specific anatomical model; and - determining the measure of mechanical interaction at or around the estimated location of the conduction system.
A shaft seal assembly (10, 110), comprising: a metal case (12, 112) having a wall (14, 114) extending cylindrically about a central axis (16, 116) with an annular leg (18, 118) extending radially inwardly from said wall (14, 114) toward said central axis (16, 116); an elastomenc material (20, 120) bonded to said leg (18, 118); a PTFE seal element (22, 122) attached to said elastomeric material (20, 120) at a bond joint (24, 124), said bond joint (24, 124) being spaced radially inwardly from said leg (18, 118) and in radial inward alignment with said leg (18, 118), and wherein said bond joint (24, 124) extends obliquely to said central axis (16, 116). a metal case (12, 112) having a wall (14, 114) extending cylindrically about a central axis (16, 116) with an annular leg (18, 118) extending radially inwardly from said wall (14, 114) toward said central axis (16, 116); an elastomenc material (20, 120) bonded to said leg (18, 118); a PTFE seal element (22, 122) attached to said elastomeric material (20, 120) at a bond joint (24, 124), said bond joint (24, 124) being spaced radially inwardly from said leg (18, 118) and in radial inward alignment with said leg (18, 118), and wherein said bond joint (24, 124) extends obliquely to said central axis (16, 116).
An allylic oxidation process comprising: forming a mixture containing α-Guaiene and an iron -X porphyrin complex catalyst wherein X is selected from the group consisting of Cl, Br, I, mesylates, triflates, and carboxylates, in a sustainable solvent selected from the group consisting of water, acetone, ethanol, 2-propanol, ethyl acetate, isopropyl acetate, methanol, methyl ethyl ketone, 1-butanol, t-butanol, cyclohexane, heptane, toluene, and mixtures thereof, and / or a sustainable solvent selected from the group consisting of methylcyclohexane, methyl t-butyl ether, isooctane, acetonitrile, xylenes, dimethyl sulfoxide, acetic acid, ethylene glycol and mixtures thereof, introducing molecular oxygen into the mixture, and effecting allylic oxidation to produce an α,β-unsaturated ketone, Rotundone. forming a mixture containing α-Guaiene and an iron -X porphyrin complex catalyst wherein X is selected from the group consisting of Cl, Br, I, mesylates, triflates, and carboxylates, in a sustainable solvent selected from the group consisting of water, acetone, ethanol, 2-propanol, ethyl acetate, isopropyl acetate, methanol, methyl ethyl ketone, 1-butanol, t-butanol, cyclohexane, heptane, toluene, and mixtures thereof, and / or a sustainable solvent selected from the group consisting of methylcyclohexane, methyl t-butyl ether, isooctane, acetonitrile, xylenes, dimethyl sulfoxide, acetic acid, ethylene glycol and mixtures thereof, introducing molecular oxygen into the mixture, and effecting allylic oxidation to produce an α,β-unsaturated ketone, Rotundone.
Component, in particular for a battery arrangement, comprising at least one conductor track on a substrate, wherein the conductor track can be electrically isolated by means of a pyrotechnic charge arranged on or in the substrate and a trigger device functionally connected to said pyrotechnic charge, wherein a bypass device is associated with the electrically isolatable conductor track, by way of which bypass device a previously absent electrical connection can be made, characterized in that the bypass device comprises at least one diode, wherein the diode can be switched on at the same time as the electrical isolation of the conductor track and can make a further flow of current in a battery string possible.
A testing apparatus, including a plurality of 1-axis testing structures therein, each 1-axis testing structure comprising: an actuator (1, 2, 3), which is configured to move linearly, thereby to apply a load onto a test body; an actuator fixing base (40, 41, 42), which is configured to fix said actuator at a predetermined position; a reaction base (7, 8, 9) comprising a chucking tool, which is configured to chuck a test piece, in a pair with another chucking tool, which is provided at end portion of said actuator (1, 2, 3); and a base (4, 5, 6), which is configured to connect said actuator fixing base (40, 41, 42) and said reaction base (7, 8, 9), wherein said base (4, 5, 6) of one of said plurality of 1-axis testing structures is configured to be movable along its testing axis and with respect to the base (4, 5, 6) of another one of said plurality of 1-axis testing structures, and wherein all said testing axes (13, 14, 15), each almost passing through an axial center of the each actuator (1, 2, 3), come across at one point, and said 1-axis testing structures are arranged so that they are included in a same plane. an actuator (1, 2, 3), which is configured to move linearly, thereby to apply a load onto a test body; an actuator fixing base (40, 41, 42), which is configured to fix said actuator at a predetermined position; a reaction base (7, 8, 9) comprising a chucking tool, which is configured to chuck a test piece, in a pair with another chucking tool, which is provided at end portion of said actuator (1, 2, 3); and a base (4, 5, 6), which is configured to connect said actuator fixing base (40, 41, 42) and said reaction base (7, 8, 9), wherein said base (4, 5, 6) of one of said plurality of 1-axis testing structures is configured to be movable along its testing axis and with respect to the base (4, 5, 6) of another one of said plurality of 1-axis testing structures, and wherein all said testing axes (13, 14, 15), each almost passing through an axial center of the each actuator (1, 2, 3), come across at one point, and said 1-axis testing structures are arranged so that they are included in a same plane.
A first computing system configured to perform transactions on data stored at a remote storage system, the remote storage system comprising a key/value store, the first computing system comprising: a database client, wherein the database client comprises an interface configured to allow a user to request database operations using the database client; and a database engine coupled to the database client, and configured to receive requests for database operations from the database client; wherein the database engine is configured to obtain and operate on transaction state stored as one or more key/value pairs in the key/value store at the remote storage system; wherein the database engine is configured to transactionally perform data operations, using the transaction state, on data stored as one or more data key/value pairs in the key/value store; and characterised by the first computing system being further configured for: receiving a notification that a second computing system has begun a transaction on data in the one or more key/value pairs, and that the transaction has not been committed or aborted; and resuming the transaction of the second computing system using the transaction state, including at least one of performing data operations on the data in the one or more data key/value pairs, aborting the transaction, or committing the transaction. a database client, wherein the database client comprises an interface configured to allow a user to request database operations using the database client; and a database engine coupled to the database client, and configured to receive requests for database operations from the database client; wherein the database engine is configured to obtain and operate on transaction state stored as one or more key/value pairs in the key/value store at the remote storage system; wherein the database engine is configured to transactionally perform data operations, using the transaction state, on data stored as one or more data key/value pairs in the key/value store; and characterised by the first computing system being further configured for: receiving a notification that a second computing system has begun a transaction on data in the one or more key/value pairs, and that the transaction has not been committed or aborted; and resuming the transaction of the second computing system using the transaction state, including at least one of performing data operations on the data in the one or more data key/value pairs, aborting the transaction, or committing the transaction. receiving a notification that a second computing system has begun a transaction on data in the one or more key/value pairs, and that the transaction has not been committed or aborted; and resuming the transaction of the second computing system using the transaction state, including at least one of performing data operations on the data in the one or more data key/value pairs, aborting the transaction, or committing the transaction.
Duplex ferritic austenitic stainless steel having high formability utilizing the TRIP effect and high corrosion resistance with the high pitting resistance equivalent, characterized in that the duplex stainless steel contains less than 0,04 weight % carbon, 0,2 - 0,8 weight % silicon, 0,3 - 2,0 weight % manganese, 14,0 - 19,0 weight % chromium, 2,0 - 5,0 weight % nickel, 4,0 - 7,0 weight % molybdenum, less than 4,5 weight % tungsten, 0,1 - 1,5 weight % copper, 0,14 - 0,23 weight % nitrogen, optionally contains one or more added elements: less than 0,04 weight % Al, less than 0,004 weight % B, less than 0,004 weight % Ca, less than 0,1 weight % Ce, up to 1 weight % Co, up to 0,1 weight % Nb, up to 0,1 weight % Ti, up to 0,2 weight % V, the rest being iron and inevitable impurities less than 0,010 weight %, preferably less than 0,005 weight % S, less than 0,040 weight % P so that the sum (S+P) is less than 0,04 weight %, and the total oxygen content is below 100 ppm occurring in stainless steels, and that the co-effect of the chromium, molybdenum and tungsten contents in weight % is in the range of 20<(Cr+Mo+0,5W)<23,5, where the ratio Cr/(Mo+0,5W) is in the range of 2 - 4,75, and the pitting resistance equivalent value is in the range of 35 - 42, the M d30 temperature is at the range of (-30°C) - (+90 °C), where the formulas of PRE = %Cr + 3,3*(%Mo+0,5%W) + 30*%N - %Mn and the Md30 = 551-462(C+N)-9,2Si-8,1Mn-13,7Cr-29(Ni+Cu)-18,5Mo-68Nb when annealed at the temperature of 1050 °C.
A donor vector suitable for use in producing a disease model mouse, comprising a fragment of a target gene, wherein the target gene is contained in the mouse genome and comprises n exons, wherein n represents the number of exons contained in the gene, and wherein n exons in the fragment of the target gene are replaced respectively with exons of the corresponding human target gene and the introns in the fragment of the target gene have mouse nucleotide sequences of the target gene, wherein the target gene is the transthyretin gene.
Electric installation device, such as a switch or button, for mounting in an installation opening along a mounting direction, having at least one base part with at least one receptacle in which a contact housing is arranged, wherein the contact housing has a clamping spring to allow at least one electrical wire to be clamped in, wherein a pivotable release lever is arranged outside an outer wall of the base part that extends parallel to the mounting direction in the region of the receptable, wherein, in a basic position of the release lever, an electrical line introduced into the contact housing is fixed by the clamping spring of the contact housing, wherein, in a release position of the release lever, the clamping spring is actuated and frees the electrical wire, wherein the release lever has a plug on an underside which faces the outer wall of the base part, wherein a cutout in the outer wall is arranged in the region of the plug, wherein the plug, the cutout, the contact housing and the clamping spring are arranged in such a way that, in the released position of the release lever, the plug actuates the clamping spring of the contact housing through the cutout to free the electrical wire, characterized in that the release lever and the base part are formed in one piece, and the plug has a latching extension projecting from the plug, wherein, in the basic position without an electrical wire introduced, the latching extension is situated within the base part and is in latching operative connection with a part of the edge of the outer wall in the region of the cutout, wherein the operative connection prevents the latching extension from coming out of the base part.
A computer-implemented method comprising: receiving an alarm, the alarm comprising failure conditions that are indicative of a network failure in a data center, the alarm generated by a network infrastructure device, the network infrastructure device being one of a switch, a router, a re-router, a gateway, a hub, or a bridge; responsive to receiving the alarm, accessing historical data, the historical data comprising a failure symptom of the network failure and troubleshooting options previously undertaken to mitigate the network failure; mapping the failure conditions of the alarm to the failure symptom in the historical data; responsive to mapping the failure conditions of the alarm to the failure symptom, identifying the troubleshooting options; assigning respective labels to the troubleshooting options, the labels indicative of respective probabilities that the troubleshooting options will mitigate the failure symptom; and outputting the plurality of troubleshooting options and their respective labels; wherein the method further comprises, responsive to receiving the alarm, identifying a failing device that causes the network failure, wherein the mapping of the failure conditions of the alarm to the failure symptom in the historical data is based upon the identifying of the failing device, and wherein the identifying of the troubleshooting options is based upon the identifying of the failing device. receiving an alarm, the alarm comprising failure conditions that are indicative of a network failure in a data center, the alarm generated by a network infrastructure device, the network infrastructure device being one of a switch, a router, a re-router, a gateway, a hub, or a bridge; responsive to receiving the alarm, accessing historical data, the historical data comprising a failure symptom of the network failure and troubleshooting options previously undertaken to mitigate the network failure; mapping the failure conditions of the alarm to the failure symptom in the historical data; responsive to mapping the failure conditions of the alarm to the failure symptom, identifying the troubleshooting options; assigning respective labels to the troubleshooting options, the labels indicative of respective probabilities that the troubleshooting options will mitigate the failure symptom; and outputting the plurality of troubleshooting options and their respective labels;
A TGFβ antagonist for use in a method for inhibiting breast cancer associated tumor growth in a subject, the method comprising administering to said subject a therapeutically effective amount of the TGFβ antagonist in combination with capecitabine and ixabepilone, wherein the administration of said TGFβ antagonist enhances the efficacy of capecitabine and ixabepilone to inhibit said breast cancer associated tumor growth.
Joining process for producing positively bonded connections between metal parts (1, 4; 21, 24; 51, 54), characterised by the following steps: embossing of at least one impression (2; 22; 52) into a joining part carrier (1; 21; 51), the impression (2; 22; 52) having a step-like edge region (5, 25; 25, 26); 55, 56) with a course which corresponds to a predetermined joining seam course, applying a joining part (4; 24; 54) to the joining part carrier (1; 21; 51), wherein a connecting region (10; 32) of the joining part (4; 24; 54) is located adjacent to the edge region (5, 6; 25, 26; 52); 55, 56), carrying out a joining operation to create a joining zone between the step-like edge region (5, 6; 25, 26; 55, 56) of the impression (2; 22; 52) and the connecting region (10; 32) of the joining part (4; 24; 54) adjoining the edge region (5, 6; 25, 26; 55, 56), the joining process being carried out as a gluing process and/or as a laser welding process or as a gas shielded arc welding process for metal or as a TIG welding process.
A glucose-responsive injectable formulation for delivering insulin to a subject in need thereof, comprising pH-responsive polymeric microgels having entrapped therein (a) insulin, (b) glucose oxidase entrapped in or bound to the microgels, and (c) an agent that reduces hydrogen peroxide, entrapped in or bound to the microgels, wherein the glucose oxidase and/or the agent that reduces hydrogen peroxide are encapsulated in nanogels, then encapsulated within the microgels, wherein the polymeric microgel expands when pH decreases from physiological pH and shrinks when pH increases towards physiological pH, thereby releasing insulin at a rate corresponding to the glucose concentration, and wherein the average microgel particle size is between 100 to 1000μm as determined by dynamic light scattering. (a) insulin, (b) glucose oxidase entrapped in or bound to the microgels, and (c) an agent that reduces hydrogen peroxide, entrapped in or bound to the microgels,
A method, comprising: at a first base station of a network that is configured to operate in a carrier aggregation mode, the first base station operating as a primary cell: generating a list of a plurality of secondary cells, wherein the plurality of secondary cells are one of femtocells and picocells of an LTE network, and each of the secondary cells being associated with a base station separated from the first base station; sending the list of the plurality of secondary cells to a user equipment, UE,; receiving a measurement results report from a user equipment, UE,, wherein the measurement results report includes signal quality measurements for the primary cell and the plurality of secondary cells; selecting a first frequency of the primary cell as a primary component carrier and a second frequency of one of the secondary cells as a secondary component carrier for the UE based on the signal quality measurements of the measurement results report, wherein a coverage area associated with the second frequency of one of the secondary cells is within a coverage area associated with the first frequency of the primary cell; and sending the selection to the UE, wherein the primary cell transmits first data on the primary component carrier to the UE and the secondary cell transmits second data on the secondary component carrier to the UE. generating a list of a plurality of secondary cells, wherein the plurality of secondary cells are one of femtocells and picocells of an LTE network, and each of the secondary cells being associated with a base station separated from the first base station; sending the list of the plurality of secondary cells to a user equipment, UE,; receiving a measurement results report from a user equipment, UE,, wherein the measurement results report includes signal quality measurements for the primary cell and the plurality of secondary cells; selecting a first frequency of the primary cell as a primary component carrier and a second frequency of one of the secondary cells as a secondary component carrier for the UE based on the signal quality measurements of the measurement results report, wherein a coverage area associated with the second frequency of one of the secondary cells is within a coverage area associated with the first frequency of the primary cell; and sending the selection to the UE, wherein the primary cell transmits first data on the primary component carrier to the UE and the secondary cell transmits second data on the secondary component carrier to the UE.