A compound selected from compounds of the following formula, and pharmaceutically acceptable salts, hydrates, and solvates thereof: wherein: - W is independently -Y; - Y is independently -Y 1, -Y 2, -Y 3, -Y 4, or -Y 5; - Y 1 is independently -OH; - Y 2 is independently Y 2A, - -Y 2B, or -Y 2c; - Y 3 is independently -Y 3A, -Y 3B, or -Y 3C; - Y 4 is independently -F, -Cl, -Br, or -I; - Y 5 is independently -CN; wherein: - Y 2A is independently -OR YA; - Y 2B is independently -OR YB; - Y 2C is independently -OR YC; - Y 3A is independently -R YA; - Y 3B is independently -R YB; - Y 3C is independently -R YC; wherein: each -R YA is independently saturated aliphatic C 1-6 alkyl; each -R YB is independently saturated aliphatic halo-C 1-6 alkyl; each -R YC is independently saturated aliphatic hydroxy-C 1-6 alkyl; and wherein: each of -J 1, -J 2, -J 3, and -J 4 is -H; or each of -J 2 and -J 4 is -H; and -J 1 and -J 3 taken together form -CH 2 - or -CH 2 CH 2 -; or each of -J 1 and -J 3 is -H; and -J 2 and -J 4 taken together form -CH 2 - or -CH 2 CH 2 -; or each of -J 2 and -J 3 is -H; and -J 1 and -J 4 taken together form -CH 2 - or -CH 2 CH 2 -; and wherein: - R N is independently -H or -R NN; - R NN is independently saturated aliphatic C 1-6 alkyl; and wherein: - R B1 is independently -H or -R BB; - R B2 is independently -H or -R BB; wherein: each -R BB is independently -R BB1, -R BB2, or -R BB3; wherein: each -R BB1 is independently saturated aliphatic C 1-6 alkyl, and is optionally substituted with one or more substituents selected from -F, -OH, -OR BBB, -OCH 2 F, -OCHF 2, -OCF 3, -NH 2, -NHR BBB, and -NR BBB 2; wherein each -R BBB is independently saturated aliphatic C 1-4 alkyl; each -R BB2 is independently -F, -Cl, -Br, or -I; each-R BB3 is independently -CN; and wherein: n is independently 0, 1, 2, 3, 4, or 5; each -R F is independently -R Z, -F, -Cl, -Br, -I, -CF 3, -OH, -OR Z, -OCF 3, -SR Z, -S(=O) 2 R Z, or -CN; and each -R Z is independently saturated aliphatic C 1-6 alkyl, and is optionally substituted with one or more substituents selected from -F, -Cl, -OH, -OR ZZ, -OCH 2 F, -OCHF 2, and -OCF 3; wherein each -R ZZ is independently saturated aliphatic C 1-4 alkyl. - W is independently -Y; - Y is independently -Y 1, -Y 2, -Y 3, -Y 4, or -Y 5; - Y 1 is independently -OH; - Y 2 is independently Y 2A, - -Y 2B, or -Y 2c; - Y 3 is independently -Y 3A, -Y 3B, or -Y 3C; - Y 4 is independently -F, -Cl, -Br, or -I; - Y 5 is independently -CN; - Y 2A is independently -OR YA; - Y 2B is independently -OR YB; - Y 2C is independently -OR YC; - Y 3A is independently -R YA; - Y 3B is independently -R YB; - Y 3C is independently -R YC; each -R YA is independently saturated aliphatic C 1-6 alkyl; each -R YB is independently saturated aliphatic halo-C 1-6 alkyl; each -R YC is independently saturated aliphatic hydroxy-C 1-6 alkyl; each of -J 1, -J 2, -J 3, and -J 4 is -H; or each of -J 2 and -J 4 is -H; and -J 1 and -J 3 taken together form -CH 2 - or -CH 2 CH 2 -; or each of -J 1 and -J 3 is -H; and -J 2 and -J 4 taken together form -CH 2 - or -CH 2 CH 2 -; or each of -J 2 and -J 3 is -H; and -J 1 and -J 4 taken together form -CH 2 - or -CH 2 CH 2 -; - R N is independently -H or -R NN; - R NN is independently saturated aliphatic C 1-6 alkyl; - R B1 is independently -H or -R BB; - R B2 is independently -H or -R BB; each -R BB is independently -R BB1, -R BB2, or -R BB3; each -R BB1 is independently saturated aliphatic C 1-6 alkyl, and is optionally substituted with one or more substituents selected from -F, -OH, -OR BBB, -OCH 2 F, -OCHF 2, -OCF 3, -NH 2, -NHR BBB, and -NR BBB 2; wherein each -R BBB is independently saturated aliphatic C 1-4 alkyl; each -R BB2 is independently -F, -Cl, -Br, or -I; each-R BB3 is independently -CN; n is independently 0, 1, 2, 3, 4, or 5; each -R F is independently -R Z, -F, -Cl, -Br, -I, -CF 3, -OH, -OR Z, -OCF 3, -SR Z, -S(=O) 2 R Z, or -CN; and each -R Z is independently saturated aliphatic C 1-6 alkyl, and is optionally substituted with one or more substituents selected from -F, -Cl, -OH, -OR ZZ, -OCH 2 F, -OCHF 2, and -OCF 3; wherein each -R ZZ is independently saturated aliphatic C 1-4 alkyl.