A detection circuit of a bridge sensor, comprising an alternating current excitation module, and a signal conditioning module, an analog-to-digital conversion module and a processing module connected in sequence; wherein the alternating current excitation module is configured to apply an alternating current excitation signal to the bridge sensor; the signal conditioning module and the analog-to-digital conversion module are configured to sequentially process an output signal from the bridge sensor; and the processing module is configured to demodulate a processed output signal, and obtain a detection information of the bridge sensor according to a demodulated output signal; wherein the signal conditioning module comprises an instrumentation amplifier and an anti-alias filter; first input terminals (121-1, 121-2) of the instrumentation amplifier are connected to output terminals (21-3, 21-4) of the bridge sensor, respectively, an output terminal of the instrumentation amplifier is connected to an input terminal of the anti-alias filter, and an output terminal of the anti-alias filter is connected to an input terminal of the analog-to-digital conversion module; characterised in that the signal conditioning module further comprises a cancellation circuit; the cancellation circuit is connected to second input terminals (121-3, 121-4) of the instrumentation amplifier, and the cancellation circuit is configured such that a magnitude of a voltage output from the instrumentation amplifier meets a preset requirement in the case when no external force acts on the bridge sensor; wherein the preset requirement comprises: a difference between the magnitude of the voltage output from the instrumentation amplifier and a magnitude of a reference voltage input to the instrumentation amplifier is zero, and the reference voltage is a common mode voltage provided by the analog-to-digital conversion module. an alternating current excitation module, and a signal conditioning module, an analog-to-digital conversion module and a processing module connected in sequence; wherein the alternating current excitation module is configured to apply an alternating current excitation signal to the bridge sensor; the signal conditioning module and the analog-to-digital conversion module are configured to sequentially process an output signal from the bridge sensor; and the processing module is configured to demodulate a processed output signal, and obtain a detection information of the bridge sensor according to a demodulated output signal; wherein the signal conditioning module comprises an instrumentation amplifier and an anti-alias filter; first input terminals (121-1, 121-2) of the instrumentation amplifier are connected to output terminals (21-3, 21-4) of the bridge sensor, respectively, an output terminal of the instrumentation amplifier is connected to an input terminal of the anti-alias filter, and an output terminal of the anti-alias filter is connected to an input terminal of the analog-to-digital conversion module; characterised in that the signal conditioning module further comprises a cancellation circuit; the cancellation circuit is connected to second input terminals (121-3, 121-4) of the instrumentation amplifier, and the cancellation circuit is configured such that a magnitude of a voltage output from the instrumentation amplifier meets a preset requirement in the case when no external force acts on the bridge sensor; wherein the preset requirement comprises: a difference between the magnitude of the voltage output from the instrumentation amplifier and a magnitude of a reference voltage input to the instrumentation amplifier is zero, and the reference voltage is a common mode voltage provided by the analog-to-digital conversion module.