A retractable luer lock system comprising: a male tubing fitting extending along a longitudinal axis and having a first internal bore and an end portion including a male plug, and wherein the male tubing fitting comprises a plurality of flanges at a proximal end thereof; a female tubing fitting with an exterior surface having a second internal bore configured to receive the male plug; and a collar disposed about the male tubing fitting and positioned to slide freely along the longitudinal axis from a first retracted position to a second locked position, wherein in the first retracted position the male and female tubing fittings are unlocked with respect to each other such that the male plug is removably insertable into the second internal bore of the female tubing fitting, and in the second locked position the male and female fittings are locked with respect to each other such that the male plug is prevented from being removed from the second internal bore of the female tubing fitting, characterized in that the collar includes an elastically deformable portion that deforms in order to slidably position the collar along the longitudinal axis from the first retracted position to the second locked position, wherein the elastically deformable portion includes a tapered lip that deforms outwardly away from the longitudinal axis, wherein the male tubing fitting includes a proximal retention member on an exterior surface thereof that is adapted to interface with the tapered lip to selectively retain the collar in the first retracted position, wherein the elastically deformable portion includes slits that interrupt the tapered lip thereby allowing the tapered lip to deform outwardly from the longitudinal axis to slide the collar beyond the selective retainment of the proximal retention member, and wherein the tapered lip is able to pass beyond the selective retainment of the proximal retention member, and move along the exterior surface towards the second locked position; and wherein the collar is rotatable about the longitudinal axis with respect to the male tubing fitting, such that the collar does not lock the female and male tubing fittings (102,104) together when in the first retracted position. a male tubing fitting extending along a longitudinal axis and having a first internal bore and an end portion including a male plug, and wherein the male tubing fitting comprises a plurality of flanges at a proximal end thereof; a female tubing fitting with an exterior surface having a second internal bore configured to receive the male plug; and a collar disposed about the male tubing fitting and positioned to slide freely along the longitudinal axis from a first retracted position to a second locked position, wherein in the first retracted position the male and female tubing fittings are unlocked with respect to each other such that the male plug is removably insertable into the second internal bore of the female tubing fitting, and in the second locked position the male and female fittings are locked with respect to each other such that the male plug is prevented from being removed from the second internal bore of the female tubing fitting, characterized in that the collar includes an elastically deformable portion that deforms in order to slidably position the collar along the longitudinal axis from the first retracted position to the second locked position, wherein the elastically deformable portion includes a tapered lip that deforms outwardly away from the longitudinal axis, wherein the male tubing fitting includes a proximal retention member on an exterior surface thereof that is adapted to interface with the tapered lip to selectively retain the collar in the first retracted position, wherein the elastically deformable portion includes slits that interrupt the tapered lip thereby allowing the tapered lip to deform outwardly from the longitudinal axis to slide the collar beyond the selective retainment of the proximal retention member, and wherein the tapered lip is able to pass beyond the selective retainment of the proximal retention member, and move along the exterior surface towards the second locked position; and wherein the collar is rotatable about the longitudinal axis with respect to the male tubing fitting, such that the collar does not lock the female and male tubing fittings (102,104) together when in the first retracted position.