An integral nano-scale pump and injection valve for high performance liquid chromatography comprising: an integrated barrel-stator, said integrated barrel-stator having an elongate barrel and a stator (302, 1712), said integrated barrel-stator integrally-formed of a single piece of material, said elongate barrel having a first open end at a first end of said integrated barrel-stator and a second open end at a second end of said integrated barrel-stator and a sidewall defining an interior chamber adapted to receive a supply of fluid, said stator (302, 1712) being circular, said stator (302, 1712) having a first side, said elongate barrel second end terminating at a centerpoint of said stator (302, 1712), at said stator first side and providing an orifice (320, 1714), said stator (302, 1712) having a first stator port (304, 1716) for communication with a mobile phase supply, said stator (302, 1712) in communication with a rotor (402, 1702) at said orifice (320, 1714), said stator (302, 1712) being at said second end of said integrated barrel-stator, a longitudinal plunger slidably extending into said interior chamber at said first end of said integrated barrel-stator, said plunger being of substantially uniform cross-section; and said rotor (402, 1702) being circular, said rotor (402 1702) having a surface adjacent said stator (302, 1712), said rotor (402, 1702) having a first channel (404, 1704) in said surface, said rotor (402, 1702) being rotatable with respect to said stator (302, 1712) about said centerpoint of said stator (302, 1712) between a load position (502, 1710) and an injection position (602, 1802), said load position (502, 1710) defined by said first stator port and said orifice (320, 1714) communicating with said first channel (404, 1704), and said injection position (602, 1802) defined by said orifice (320, 1714) and a second stator port (306, 1706) communicating with said first channel (404, 1704). an integrated barrel-stator, said integrated barrel-stator having an elongate barrel and a stator (302, 1712), said integrated barrel-stator integrally-formed of a single piece of material, said elongate barrel having a first open end at a first end of said integrated barrel-stator and a second open end at a second end of said integrated barrel-stator and a sidewall defining an interior chamber adapted to receive a supply of fluid, said stator (302, 1712) being circular, said stator (302, 1712) having a first side, said elongate barrel second end terminating at a centerpoint of said stator (302, 1712), at said stator first side and providing an orifice (320, 1714), said stator (302, 1712) having a first stator port (304, 1716) for communication with a mobile phase supply, said stator (302, 1712) in communication with a rotor (402, 1702) at said orifice (320, 1714), said stator (302, 1712) being at said second end of said integrated barrel-stator, said elongate barrel having a first open end at a first end of said integrated barrel-stator and a second open end at a second end of said integrated barrel-stator and a sidewall defining an interior chamber adapted to receive a supply of fluid, said stator (302, 1712) being circular, said stator (302, 1712) having a first side, said elongate barrel second end terminating at a centerpoint of said stator (302, 1712), at said stator first side and providing an orifice (320, 1714), said stator (302, 1712) having a first stator port (304, 1716) for communication with a mobile phase supply, said stator (302, 1712) in communication with a rotor (402, 1702) at said orifice (320, 1714), said stator (302, 1712) being at said second end of said integrated barrel-stator, a longitudinal plunger slidably extending into said interior chamber at said first end of said integrated barrel-stator, said plunger being of substantially uniform cross-section; and said rotor (402, 1702) being circular, said rotor (402 1702) having a surface adjacent said stator (302, 1712), said rotor (402, 1702) having a first channel (404, 1704) in said surface, said rotor (402, 1702) being rotatable with respect to said stator (302, 1712) about said centerpoint of said stator (302, 1712) between a load position (502, 1710) and an injection position (602, 1802), said load position (502, 1710) defined by said first stator port and said orifice (320, 1714) communicating with said first channel (404, 1704), and said injection position (602, 1802) defined by said orifice (320, 1714) and a second stator port (306, 1706) communicating with said first channel (404, 1704). rotatable with respect to said stator (302, 1712) about said centerpoint of said stator (302, 1712) between a load position (502, 1710) and an injection position (602, 1802), said load position (502, 1710) defined by said first stator port and said orifice (320, 1714) communicating with said first channel (404, 1704), and said injection position (602, 1802) defined by said orifice (320, 1714) and a second stator port (306, 1706) communicating with said first channel (404, 1704).