A device for delivering a predetermined amount V sub of at least one substance, within at least one body cavity of a subject, said device comprising: at least one predetermined volume sized and shaped for containing said predetermined amount V sub of said at least one substance; a delivery end for placement in proximity to said body cavity, said delivery end being in fluid communication with said at least one predetermined volume; said delivery end comprises at least one orifice of diameter D [mm]; a fluid tight chamber configured to contain a predetermined amount V gas of a pressurized gas at a predetermined pressure, P gas [barg]; at least one valve mechanically connectable to said predetermined volume, characterized by at least two configurations: (i) an active configuration in which said valve enables delivery of predetermined amount V sub of said at least one substance from said volume to said body cavity via said delivery end; and, (ii) an inactive configuration, in which said valve prevents delivery of said predetermined amount V sub of said at least one substance from said volume to said body cavity; said valve is reconfigurable from said inactive configuration to said active configuration within a predetermined period of time, dt, in response to activation of the same; said pressurized gas, once said valve is reconfigured from said inactive configuration to said active configuration, is configured to entrain said at least one substance and deliver the same via said orifice in said delivery end within said body cavity; and said device is configured to deliver said predetermined amount V sub of said at least one substance and said predetermined volume V gas of said pressurized gas through said at least one orifice within a predetermined time dt deliver; characterized in that the device comprises a body having an air chamber gate with a first gate O-ring at a proximal end of the air chamber gate and a second gate O-ring at a distal end of the air chamber gate, the first gate O-ring and the second gate O-ring providing airtight seals before reconfiguration of the valve from said inactive configuration to said active configuration so that pressurized gas is storable in the fluid tight chamber; and the valve is configured to be reconfigured from said inactive configuration to said active configuration by moving the air chamber gate to open up a gap, allowing the pressurized gas to exit the fluid tight chamber through the gap. at least one predetermined volume sized and shaped for containing said predetermined amount V sub of said at least one substance; a delivery end for placement in proximity to said body cavity, said delivery end being in fluid communication with said at least one predetermined volume; said delivery end comprises at least one orifice of diameter D [mm]; a fluid tight chamber configured to contain a predetermined amount V gas of a pressurized gas at a predetermined pressure, P gas [barg]; at least one valve mechanically connectable to said predetermined volume, characterized by at least two configurations: (i) an active configuration in which said valve enables delivery of predetermined amount V sub of said at least one substance from said volume to said body cavity via said delivery end; and, (ii) an inactive configuration, in which said valve prevents delivery of said predetermined amount V sub of said at least one substance from said volume to said body cavity; said valve is reconfigurable from said inactive configuration to said active configuration within a predetermined period of time, dt, in response to activation of the same; said pressurized gas, once said valve is reconfigured from said inactive configuration to said active configuration, is configured to entrain said at least one substance and deliver the same via said orifice in said delivery end within said body cavity; and said device is configured to deliver said predetermined amount V sub of said at least one substance and said predetermined volume V gas of said pressurized gas through said at least one orifice within a predetermined time dt deliver; characterized in that the device comprises a body having an air chamber gate with a first gate O-ring at a proximal end of the air chamber gate and a second gate O-ring at a distal end of the air chamber gate, the first gate O-ring and the second gate O-ring providing airtight seals before reconfiguration of the valve from said inactive configuration to said active configuration so that pressurized gas is storable in the fluid tight chamber; and the valve is configured to be reconfigured from said inactive configuration to said active configuration by moving the air chamber gate to open up a gap, allowing the pressurized gas to exit the fluid tight chamber through the gap.