A system for detecting anatomical structures and therapeutic neuromodulation in a nasal region of a human patient, the system comprising: a shaft having a proximal portion and a distal portion, wherein the shaft is configured to locate the distal portion intraluminally at a target site within a nasal cavity inferior to a sphenopalatine foramen of the human patient; an evaluation/modulation assembly at the distal portion of the shaft, wherein the evaluation/modulation assembly comprises a plurality of electrodes configured to emit stimulating energy to tissue at the target site at frequencies for locating target neural structures and detect bioelectric properties in response to the stimulating energy, wherein the plurality of electrodes are configured to detect bioelectric properties of non-target anatomical structures at the target site, and wherein the plurality of electrodes are configured to apply therapeutic neuromodulation energy to target neural structures; and a console including a controller having a computer-readable medium carrying instructions, which when executed by the controller, cause the console to: apply, via at least a portion of the plurality of electrodes, stimulating energy to tissue at the target site, wherein applying stimulating energy comprises applying simulation energy with at least two different frequencies; detect, via at least a portion of the plurality of electrodes, responses to the applied stimulating energy; determine locations and morphology of the target neural structures and locations and morphology of non-target anatomical structures at the target site based on the detected responses; generate an ablation pattern based on the determined locations and morphology of the target neural structures and the determined location and morphology of the non-target anatomical structures, wherein the ablation pattern comprises a region of influence for each of the plurality of electrodes, and wherein the ablation pattern targets the target neural structures and avoids the non-target anatomical structures; and cause the evaluation/modulation assembly to apply, via at least a portion of the plurality of electrodes, therapeutic neuromodulation energy according to the generated ablation pattern to avoid the locations of the non-target anatomical structures. a shaft having a proximal portion and a distal portion, wherein the shaft is configured to locate the distal portion intraluminally at a target site within a nasal cavity inferior to a sphenopalatine foramen of the human patient; an evaluation/modulation assembly at the distal portion of the shaft, wherein the evaluation/modulation assembly comprises a plurality of electrodes configured to emit stimulating energy to tissue at the target site at frequencies for locating target neural structures and detect bioelectric properties in response to the stimulating energy, wherein the plurality of electrodes are configured to detect bioelectric properties of non-target anatomical structures at the target site, and wherein the plurality of electrodes are configured to apply therapeutic neuromodulation energy to target neural structures; and a console including a controller having a computer-readable medium carrying instructions, which when executed by the controller, cause the console to: apply, via at least a portion of the plurality of electrodes, stimulating energy to tissue at the target site, wherein applying stimulating energy comprises applying simulation energy with at least two different frequencies; detect, via at least a portion of the plurality of electrodes, responses to the applied stimulating energy; determine locations and morphology of the target neural structures and locations and morphology of non-target anatomical structures at the target site based on the detected responses; generate an ablation pattern based on the determined locations and morphology of the target neural structures and the determined location and morphology of the non-target anatomical structures, wherein the ablation pattern comprises a region of influence for each of the plurality of electrodes, and wherein the ablation pattern targets the target neural structures and avoids the non-target anatomical structures; and cause the evaluation/modulation assembly to apply, via at least a portion of the plurality of electrodes, therapeutic neuromodulation energy according to the generated ablation pattern to avoid the locations of the non-target anatomical structures. apply, via at least a portion of the plurality of electrodes, stimulating energy to tissue at the target site, wherein applying stimulating energy comprises applying simulation energy with at least two different frequencies; detect, via at least a portion of the plurality of electrodes, responses to the applied stimulating energy; determine locations and morphology of the target neural structures and locations and morphology of non-target anatomical structures at the target site based on the detected responses; generate an ablation pattern based on the determined locations and morphology of the target neural structures and the determined location and morphology of the non-target anatomical structures, wherein the ablation pattern comprises a region of influence for each of the plurality of electrodes, and wherein the ablation pattern targets the target neural structures and avoids the non-target anatomical structures; and cause the evaluation/modulation assembly to apply, via at least a portion of the plurality of electrodes, therapeutic neuromodulation energy according to the generated ablation pattern to avoid the locations of the non-target anatomical structures.