A system comprising: one or more remote analytical instruments operably coupled to one or more servers, wherein the one or more instruments are configured to transmit data from the instruments in real time, the data transmitted from the one or more instruments being collected and stored in one or more repositories on the one or more servers, wherein the data comprises flow cell related failures recorded over a period of time; wherein one or more processors associated with the one or more servers are configured to: - correlate data from individual records using cross-linked translation tables and employ the cross-linked translation tables to process the data on a dedicated server of the one or more servers; - identify one or more drivers for the flow cell related failures, wherein the one or more drivers for the flow cell related failures comprises a reduction of functionality of an auto-purge cycle in a particular version of instrument software; - deploy corrective measures for at least one of the identified one or more drivers associated with the flow cell related failures, which comprises deploying software updates increasing a number of flow cell aperture backflushes triggered by clogs. one or more remote analytical instruments operably coupled to one or more servers, wherein the one or more instruments are configured to transmit data from the instruments in real time, the data transmitted from the one or more instruments being collected and stored in one or more repositories on the one or more servers, wherein the data comprises flow cell related failures recorded over a period of time; wherein one or more processors associated with the one or more servers are configured to: - correlate data from individual records using cross-linked translation tables and employ the cross-linked translation tables to process the data on a dedicated server of the one or more servers; - identify one or more drivers for the flow cell related failures, wherein the one or more drivers for the flow cell related failures comprises a reduction of functionality of an auto-purge cycle in a particular version of instrument software; - deploy corrective measures for at least one of the identified one or more drivers associated with the flow cell related failures, which comprises deploying software updates increasing a number of flow cell aperture backflushes triggered by clogs. wherein the data comprises flow cell related failures recorded over a period of time; wherein one or more processors associated with the one or more servers are configured to: - correlate data from individual records using cross-linked translation tables and employ the cross-linked translation tables to process the data on a dedicated server of the one or more servers; - identify one or more drivers for the flow cell related failures, wherein the one or more drivers for the flow cell related failures comprises a reduction of functionality of an auto-purge cycle in a particular version of instrument software; - deploy corrective measures for at least one of the identified one or more drivers associated with the flow cell related failures, which comprises deploying software updates increasing a number of flow cell aperture backflushes triggered by clogs. - correlate data from individual records using cross-linked translation tables and employ the cross-linked translation tables to process the data on a dedicated server of the one or more servers; - identify one or more drivers for the flow cell related failures, wherein the one or more drivers for the flow cell related failures comprises a reduction of functionality of an auto-purge cycle in a particular version of instrument software; - deploy corrective measures for at least one of the identified one or more drivers associated with the flow cell related failures, which comprises deploying software updates increasing a number of flow cell aperture backflushes triggered by clogs.