mhurhangee/ep-ind-claims huggingface dataset:
A method of estimating the fraction of fetal DNA in DNA obtained from a bodily fluid of a pregnant individual, the method comprising: (a) receiving a sample of the bodily fluid; (b) extracting DNA from the sample under conditions that extract DNA of both a maternal genome and a fetal genome present in the bodily fluid; (c) sequencing the extracted DNA with a nucleic acid sequencer under conditions that produce DNA segment sequences containing one or more polymorphisms; (d) mapping the DNA segment sequences derived from sequencing the DNA in the bodily fluid to one or more designated polymorphisms on a reference sequence, wherein the mapping is performed using a computational apparatus programmed to map nucleic acid sequences to the one or more designated polymorphisms; (e) determining allele frequencies of the mapped DNA segment sequences for at least one of the designated polymorphisms; (f) classifying the at least one designated polymorphism based on a combination of the zygosity of the pregnant individual and the zygosity of the fetus; and (g) estimating the fraction of fetal DNA in the DNA obtained from the pregnant individual using the allele frequencies determined in (e) in conjunction with the classification of zygosities from (f), wherein (e)-(g) are performed on one or more processors running under program instructions for the determining, classifying and estimating, wherein the sequencing in step (c) produces DNA segment sequences containing a plurality of polymorphisms and steps (d)-(f) are performed based on the plurality of polymorphisms; and wherein the classifying in (f) classifies each of the plurality of polymorphisms into one of the following combinations: (i) the pregnant individual is homozygous and the fetus is homozygous, (ii) the pregnant individual is homozygous and the fetus is heterozygous, (iii) the pregnant individual is heterozygous and the fetus is homozygous, and (iv) the pregnant individual is heterozygous and the fetus is heterozygous. (a) receiving a sample of the bodily fluid; (b) extracting DNA from the sample under conditions that extract DNA of both a maternal genome and a fetal genome present in the bodily fluid; (c) sequencing the extracted DNA with a nucleic acid sequencer under conditions that produce DNA segment sequences containing one or more polymorphisms; (d) mapping the DNA segment sequences derived from sequencing the DNA in the bodily fluid to one or more designated polymorphisms on a reference sequence, wherein the mapping is performed using a computational apparatus programmed to map nucleic acid sequences to the one or more designated polymorphisms; (e) determining allele frequencies of the mapped DNA segment sequences for at least one of the designated polymorphisms; (f) classifying the at least one designated polymorphism based on a combination of the zygosity of the pregnant individual and the zygosity of the fetus; and (g) estimating the fraction of fetal DNA in the DNA obtained from the pregnant individual using the allele frequencies determined in (e) in conjunction with the classification of zygosities from (f),
An aircraft comprising: a window assembly comprising: a windshield oriented toward a front of the aircraft; a side window oriented toward a side of the aircraft; a post (130, 350) interposed between the windshield and the side window; and an airflow surface disposed on the post (130, 350), the airflow surface extending along a length from a leading edge proximate the windshield to a trailing edge proximate the side window, the airflow surface extending along a height between a top and a bottom, the airflow surface having a first radius of curvature proximate the leading edge and a second radius of curvature proximate the trailing edge, wherein the first radius of curvature is less than the second radius of curvature. a windshield oriented toward a front of the aircraft; a side window oriented toward a side of the aircraft; a post (130, 350) interposed between the windshield and the side window; and an airflow surface disposed on the post (130, 350), the airflow surface extending along a length from a leading edge proximate the windshield to a trailing edge proximate the side window, the airflow surface extending along a height between a top and a bottom, the airflow surface having a first radius of curvature proximate the leading edge and a second radius of curvature proximate the trailing edge, wherein the first radius of curvature is less than the second radius of curvature.
A colorimetric analytical method for determining the concentration of an oxidising analyte present in a liquid sample, which method is characterised by the steps of: a) mixing a volume of reagent with a volume of said liquid sample to form a solution, wherein said reagent contains a food dye capable of reacting with said oxidising analyte so that the reaction product in the said solution has different absorbance wavelength characteristics from the un-reacted food dye; b) measuring the absorbance characteristics of said solution at two or more wavelengths, wherein at least one of the wavelengths corresponds to the unreacted food dye and one other of the wavelengths corresponds to reacted food dye; c) determining the concentration of said reaction product of said food dye and concentration of un-reacted food dye in said solution from said absorbance measurements; and d) determining the concentration of said oxidising analyte from the concentration of said reaction product and said concentration of un-reacted food dye a) mixing a volume of reagent with a volume of said liquid sample to form a solution, wherein said reagent contains a food dye capable of reacting with said oxidising analyte so that the reaction product in the said solution has different absorbance wavelength characteristics from the un-reacted food dye; b) measuring the absorbance characteristics of said solution at two or more wavelengths, wherein at least one of the wavelengths corresponds to the unreacted food dye and one other of the wavelengths corresponds to reacted food dye; c) determining the concentration of said reaction product of said food dye and concentration of un-reacted food dye in said solution from said absorbance measurements; and d) determining the concentration of said oxidising analyte from the concentration of said reaction product and said concentration of un-reacted food dye
A coating composition comprising: an aqueous dispersion of self-crosslinkable core-shell particles, wherein the core-shell particles comprise a polymeric core at least partially encapsulated by a polymeric shell comprising urethane linkages, keto and/or aldo functional groups, and hydrazide functional groups, wherein the polymeric core is covalently bonded to at least a portion of the polymeric shell, and a hydrophobic additive comprising a wax and/or a silicon-containing compound, wherein the hydrophobic additive is non-reactive with the polymeric core and the polymeric shell. an aqueous dispersion of self-crosslinkable core-shell particles, wherein the core-shell particles comprise a polymeric core at least partially encapsulated by a polymeric shell comprising urethane linkages, keto and/or aldo functional groups, and hydrazide functional groups, wherein the polymeric core is covalently bonded to at least a portion of the polymeric shell, and a hydrophobic additive comprising a wax and/or a silicon-containing compound, wherein the hydrophobic additive is non-reactive with the polymeric core and the polymeric shell.
A method of automatically generating a header file to define memory pools for deterministic memory allocation, the method comprising using at least one hardware processor to: receive bitcode representing compiled source code of an application, wherein the source code comprises an allocation function for allocating memory that calls a dummy function using one or more parameters, wherein the one or more parameters comprise an identifier of a memory pool; and, automatically, scan the bitcode to detect each call to the dummy function in the bitcode, for each detected call to the dummy function, extract the one or more parameters used in the detected call to the dummy function, and generate an allocation record, comprising the identifier of the memory pool, from the extracted one or more parameters, and generate a header file based on the generated allocation records, wherein the header file comprises a definition of one or more buckets and a definition of each of one or more memory pools, and wherein the definition of each of the one or more memory pools identifies at least one of the one or more buckets. receive bitcode representing compiled source code of an application, wherein the source code comprises an allocation function for allocating memory that calls a dummy function using one or more parameters, wherein the one or more parameters comprise an identifier of a memory pool; and, automatically, scan the bitcode to detect each call to the dummy function in the bitcode, for each detected call to the dummy function, extract the one or more parameters used in the detected call to the dummy function, and generate an allocation record, comprising the identifier of the memory pool, from the extracted one or more parameters, and generate a header file based on the generated allocation records, wherein the header file comprises a definition of one or more buckets and a definition of each of one or more memory pools, and wherein the definition of each of the one or more memory pools identifies at least one of the one or more buckets.
A compound selected from the group consisting of a compound of formula, and pharmaceutically acceptable salts, hydrates, and solvates thereof: wherein, A is and R 8 is hydrogen, halogen, or C 1-3 alkyl; R 1 and R 2 are each independently hydrogen or C 1-3 alkyl; and R 3 to R 7 are each independently hydrogen, halogen, cyano, nitro, or C 1-3 haloalkyl; and wherein R 3 and R 7 are each independently halogen, cyano, nitro, or C 1-3 haloalkyl. A is and R 8 is hydrogen, halogen, or C 1-3 alkyl; R 1 and R 2 are each independently hydrogen or C 1-3 alkyl; and R 3 to R 7 are each independently hydrogen, halogen, cyano, nitro, or C 1-3 haloalkyl; and wherein R 3 and R 7 are each independently halogen, cyano, nitro, or C 1-3 haloalkyl.
A method for controlling the operation of a diesel internal combustion engine comprising the following steps in which: - a temperature (Tfc) of the heat-transport fluid of a temperature control circuit of the engine is determined, - an ambient atmospheric pressure (Patm) is determined characterized in that it comprises the steps in which: - a modified temperature (Tm) of said heat-transport fluid is calculated from said temperature (Tfc) of the heat-transport fluid and of said ambient atmospheric pressure (Patm) - operating parameters of the engine are controlled from said modified temperature (Tm) of said heat-transport fluid. - a temperature (Tfc) of the heat-transport fluid of a temperature control circuit of the engine is determined, - an ambient atmospheric pressure (Patm) is determined characterized in that it comprises the steps in which: - a modified temperature (Tm) of said heat-transport fluid is calculated from said temperature (Tfc) of the heat-transport fluid and of said ambient atmospheric pressure (Patm) - operating parameters of the engine are controlled from said modified temperature (Tm) of said heat-transport fluid.
A monitoring method for an industrial control system used for remote monitoring and/or for controlling an industrial process and comprising industrial devices such as industrial controllers and/or field devices, wherein the method comprises: - obtaining first network traffic transmitted in the industrial control system in a passive monitoring manner; - determining whether it is necessary to monitor the industrial control system in an active probe manner according to characteristics of industrial devices in the industrial control system in the first network traffic; - if determining that it is necessary to monitor the industrial control system in an active probe manner: - determining a target industrial device according to the characteristics of the industrial devices in the industrial control system in the first network traffic, - sending third network traffic to the determined target industrial device, and - obtaining second network traffic sent by the target industrial device in response to the third network traffic. - obtaining first network traffic transmitted in the industrial control system in a passive monitoring manner; - determining whether it is necessary to monitor the industrial control system in an active probe manner according to characteristics of industrial devices in the industrial control system in the first network traffic; - if determining that it is necessary to monitor the industrial control system in an active probe manner: - determining a target industrial device according to the characteristics of the industrial devices in the industrial control system in the first network traffic, - sending third network traffic to the determined target industrial device, and - obtaining second network traffic sent by the target industrial device in response to the third network traffic. - determining a target industrial device according to the characteristics of the industrial devices in the industrial control system in the first network traffic, - sending third network traffic to the determined target industrial device, and - obtaining second network traffic sent by the target industrial device in response to the third network traffic.
A method of operating an intermediate node for in-order message delivery in a distributed store-and-forward system comprising a plurality of intermediate nodes and an origination node having information for a destination node, the method comprising the steps of: establishing (210; 410), by the intermediate node, a first communication link with the destination node, based on the destination node coming within wireless communication range of the intermediate node or being physically connected to the intermediate node, wherein the first communication link comprises a first Open Systems Interconnection, OSI, model layer; in response to establishing the first communication link with the destination node, sending (215; 420) a request from the intermediate node to the origination node, wherein: the request is for the information to provide to the destination node, and the request is sent via a second communication link comprising a second OSI model layer different from the first OSI model layer; receiving (240; 430), by the intermediate node via the second communication link, a message to provide to the destination node; and sending (245; 440) the message from the intermediate node to the destination node via the first communication link while the first communication link is established. establishing (210; 410), by the intermediate node, a first communication link with the destination node, based on the destination node coming within wireless communication range of the intermediate node or being physically connected to the intermediate node, wherein the first communication link comprises a first Open Systems Interconnection, OSI, model layer; in response to establishing the first communication link with the destination node, sending (215; 420) a request from the intermediate node to the origination node, wherein: the request is for the information to provide to the destination node, and the request is sent via a second communication link comprising a second OSI model layer different from the first OSI model layer; the request is for the information to provide to the destination node, and the request is sent via a second communication link comprising a second OSI model layer different from the first OSI model layer; receiving (240; 430), by the intermediate node via the second communication link, a message to provide to the destination node; and sending (245; 440) the message from the intermediate node to the destination node via the first communication link while the first communication link is established.
A television device for adjusting quality of a received video image to be displayed on a display unit, comprising: an external light detection unit which detects an illuminance and a tint of an ambient light; and an image quality control unit which adjusts the quality of the video image to be displayed on the display unit, characterized in that: the external light detection unit obtains the illuminance value and the tint value corresponding to a color temperature of an external light from an output value of a first sensor for detecting an illuminance of the external light and an output value of a second sensor for detecting a tint of the external light, the first sensor is an illuminance sensor for detecting a visible light, and the second sensor is an infrared sensor for detecting an infrared light, and the image quality control unit adjusts a color temperature of the video image to be displayed so that the color temperature is increased when the illuminance value detected by the external light detection unit becomes large, and when the tint value detected by the external light detection unit becomes large. an external light detection unit which detects an illuminance and a tint of an ambient light; and an image quality control unit which adjusts the quality of the video image to be displayed on the display unit, characterized in that: the external light detection unit obtains the illuminance value and the tint value corresponding to a color temperature of an external light from an output value of a first sensor for detecting an illuminance of the external light and an output value of a second sensor for detecting a tint of the external light, the first sensor is an illuminance sensor for detecting a visible light, and the second sensor is an infrared sensor for detecting an infrared light, and the image quality control unit adjusts a color temperature of the video image to be displayed so that the color temperature is increased when the illuminance value detected by the external light detection unit becomes large, and when the tint value detected by the external light detection unit becomes large. the external light detection unit obtains the illuminance value and the tint value corresponding to a color temperature of an external light from an output value of a first sensor for detecting an illuminance of the external light and an output value of a second sensor for detecting a tint of the external light, the first sensor is an illuminance sensor for detecting a visible light, and the second sensor is an infrared sensor for detecting an infrared light, and the image quality control unit adjusts a color temperature of the video image to be displayed so that the color temperature is increased when the illuminance value detected by the external light detection unit becomes large, and when the tint value detected by the external light detection unit becomes large.
An aeroderivative gas turbine engine, comprising: - a gas generator comprised of a compressor section; and - a power turbine section, having a power turbine rotor supported by a power turbine shaft, which is mechanically uncoupled from the gas generator; wherein the power turbine shaft has an axial cavity therein, fluidly coupled with a bearing sump; wherein the bearing sump is fluidly coupled with the compressor section and houses at least one bearing supporting a shaft of the gas generator; and wherein an air venting path extends from said axial cavity and leads in a combustion gas flow path downstream of the power turbine rotor. - a gas generator comprised of a compressor section; and - a power turbine section, having a power turbine rotor supported by a power turbine shaft, which is mechanically uncoupled from the gas generator;
A microreactor for photoreactions to proceed a photoreaction of a reactant or a plurality of reactants, comprising a flow path plate on which a flow path for passing the reactant or plurality of reactants is formed, and a lid plate, wherein a fluid inlet and a fluid exit are formed to the lid plate at positions corresponding to a fluid inlet and a fluid exit of the flow path formed in the flow path plate respectively, characterised in that the flow path plate is made of black alumina which is a material having a high thermal conductivity and suppressing light reflection, the light reflectance of the flow path plate is 5.1% to 15.3% at a wavelength of light of 240 to 2600 nm, the thermal conductivity of the flow path plate is 12 to 31 W/(m·K), and the lid plate has a window frame part made of an identical material having high thermal conductivity and suppressing light reflectance as the flow path plate, and a light transmitting part made of a material allowing transmission of light and secured with the flow path plate. a flow path plate on which a flow path for passing the reactant or plurality of reactants is formed, and a lid plate, wherein a fluid inlet and a fluid exit are formed to the lid plate at positions corresponding to a fluid inlet and a fluid exit of the flow path formed in the flow path plate respectively, characterised in that the flow path plate is made of black alumina which is a material having a high thermal conductivity and suppressing light reflection, the light reflectance of the flow path plate is 5.1% to 15.3% at a wavelength of light of 240 to 2600 nm, the thermal conductivity of the flow path plate is 12 to 31 W/(m·K), and the lid plate has a window frame part made of an identical material having high thermal conductivity and suppressing light reflectance as the flow path plate, and a light transmitting part made of a material allowing transmission of light and secured with the flow path plate.
A method for monitoring the operation of a liquid delivery pen, the liquid delivery pen comprising a medication delivery module, and an electronic module (6; 30; 40) coupled to the liquid delivery pen, the electronic module (6; 30; 40) comprising a sensor element, a control element, and a storing element, the method comprising the steps of: - detecting, using the sensor element, signals generated in response to a measurable operation of the medication delivery module, - generating electronic data by processing, using the control element, electronic information derived from the detected signals, the electronic data comprising information about: - a medication delivery characteristic of at least one measurable operation of the medication delivery module, and - storing the electronic data in the storing element, characterized in that the step of generating electronic data comprises generating information about a measurable priming operation of the medication delivery module, wherein, if the medication delivery module is brought into a spatial position which causes air to rise in order to be expelled, the spatial position is detected by a positioning sensor, and wherein an expelling event with the detected spatial position of the medication delivery module is determined as a priming operation. - detecting, using the sensor element, signals generated in response to a measurable operation of the medication delivery module, - generating electronic data by processing, using the control element, electronic information derived from the detected signals, the electronic data comprising information about: - a medication delivery characteristic of at least one measurable operation of the medication delivery module, and - a medication delivery characteristic of at least one measurable operation of the medication delivery module, - storing the electronic data in the storing element,