A motorcycle comprising: a vehicle body frame including: a head pipe; a pair of main frames extending rearward from the head pipe in such a manner that the pair of main frames are spaced apart from each other in a vehicle width direction of a vehicle body; a cross member extending in the vehicle width direction and connecting rear end portions of the pair of main frames to each other; and a pair of rear frames extending rearward from the cross member and supporting a seat; and an engine connected to the pair of main frames, wherein each of the pair of main frames includes a trellis section including a plurality of pipes coupled to each other in a trellis form, and a single pipe section extending rearward from the trellis section and having a rear end joined to the cross member, wherein the trellis section is provided with a first mount to which a front portion of a cylinder head of the engine is connected, and wherein the single pipe section is provided with a second mount to which a rear portion of the cylinder head of the engine is connected, wherein each of the pair of main frames further includes an upper frame extending rearward from an upper portion of the head pipe, and a lower frame extending rearward from a lower portion of the head pipe, wherein the first mount is connected to the front portion of the cylinder head via a first bracket with a pipe shape; wherein a lower end portion of the first bracket is in contact with a fastening seat section provided on the front portion of the cylinder head from an outer side in the vehicle width direction, and fastened in the vehicle width direction to the fastening seat section by use of a bolt, the fastening seat section protruding in a forward direction and being located above exhaust ports of the cylinder head, characterized in that: one of the upper frame and the lower frame terminates at a location that is in front of a rear end of the other one of the upper frame and the lower frame, and is joined to an intermediate portion of the other one of the upper frame and the lower frame; an upper end portion of the first bracket is fastened in the vehicle width direction to the first mount by use of a bolt; and the first mount protrudes in a plate shape in a downward direction from a front portion of the lower frame. a vehicle body frame including: a head pipe; a pair of main frames extending rearward from the head pipe in such a manner that the pair of main frames are spaced apart from each other in a vehicle width direction of a vehicle body; a cross member extending in the vehicle width direction and connecting rear end portions of the pair of main frames to each other; and a pair of rear frames extending rearward from the cross member and supporting a seat; and a head pipe; a pair of main frames extending rearward from the head pipe in such a manner that the pair of main frames are spaced apart from each other in a vehicle width direction of a vehicle body; a cross member extending in the vehicle width direction and connecting rear end portions of the pair of main frames to each other; and a pair of rear frames extending rearward from the cross member and supporting a seat; and an engine connected to the pair of main frames, wherein each of the pair of main frames includes a trellis section including a plurality of pipes coupled to each other in a trellis form, and a single pipe section extending rearward from the trellis section and having a rear end joined to the cross member, wherein the trellis section is provided with a first mount to which a front portion of a cylinder head of the engine is connected, and wherein the single pipe section is provided with a second mount to which a rear portion of the cylinder head of the engine is connected, wherein each of the pair of main frames further includes an upper frame extending rearward from an upper portion of the head pipe, and a lower frame extending rearward from a lower portion of the head pipe, wherein the first mount is connected to the front portion of the cylinder head via a first bracket with a pipe shape; wherein a lower end portion of the first bracket is in contact with a fastening seat section provided on the front portion of the cylinder head from an outer side in the vehicle width direction, and fastened in the vehicle width direction to the fastening seat section by use of a bolt, the fastening seat section protruding in a forward direction and being located above exhaust ports of the cylinder head, characterized in that: one of the upper frame and the lower frame terminates at a location that is in front of a rear end of the other one of the upper frame and the lower frame, and is joined to an intermediate portion of the other one of the upper frame and the lower frame; an upper end portion of the first bracket is fastened in the vehicle width direction to the first mount by use of a bolt; and the first mount protrudes in a plate shape in a downward direction from a front portion of the lower frame. one of the upper frame and the lower frame terminates at a location that is in front of a rear end of the other one of the upper frame and the lower frame, and is joined to an intermediate portion of the other one of the upper frame and the lower frame; an upper end portion of the first bracket is fastened in the vehicle width direction to the first mount by use of a bolt; and the first mount protrudes in a plate shape in a downward direction from a front portion of the lower frame.