mhurhangee/ep-ind-claims huggingface dataset:
A tool for forming a workpiece comprising: a first layer defining an exterior tool face for forming a workpiece, a temperature control surface opposite the tool face and a plurality of discrete first fluid chambers each bounded by a part of the temperature control surface; a second layer defining a second fluid chamber; a plurality of heater assemblies each comprising a heater inlet, a heater outlet and a fluid heater disposed therebetween; in which the heater inlets are positioned within the second layer and each heater outlet is positioned within a respective first fluid chamber; and, wherein the first and second layers are configured such that flow of fluid from the first fluid chambers into the second fluid chamber is prohibited. a first layer defining an exterior tool face for forming a workpiece, a temperature control surface opposite the tool face and a plurality of discrete first fluid chambers each bounded by a part of the temperature control surface; a second layer defining a second fluid chamber; a plurality of heater assemblies each comprising a heater inlet, a heater outlet and a fluid heater disposed therebetween; in which the heater inlets are positioned within the second layer and each heater outlet is positioned within a respective first fluid chamber; and, wherein the first and second layers are configured such that flow of fluid from the first fluid chambers into the second fluid chamber is prohibited.
A radio communication system comprising: a first base station configured to transmit a first pilot signal within a first cell formed by the first base station itself; and a second base station configured to communicate with a mobile station, set, based on reception quality of the first pilot signal transmitted from the first base station, target received power of uplink data transmitted to the second base station from the mobile station and control transmission power of the uplink data by using the target received power. a first base station configured to transmit a first pilot signal within a first cell formed by the first base station itself; and a second base station configured to communicate with a mobile station, set, based on reception quality of the first pilot signal transmitted from the first base station, target received power of uplink data transmitted to the second base station from the mobile station and control transmission power of the uplink data by using the target received power.
A computational method for sampling the spatial distribution of one or more solutes and water in a defined region of space (system) comprising: 1) assigning a target concentration, N tgt, of each of the one or more solutes and water; 2) sampling the spatial distribution of the one or more solutes and water in a computationally defined region of space using Grand-Canonical Monte-Carlo (GCMC) Metropolis sampling criteria, wherein the excess chemical potential (μ ex) assigned for each of the one or more solutes, if present, and water is set to 0, if present; 3) updating μ ex of each of the one or more solutes and water from the difference in current concentration in the defined region of space (N sys) and the target (N tgt); 4) repeating steps 2) and 3) using the updated values of μ ex in step 2) to obtain a spatial distribution of the one or more solutes and water; wherein the system further comprises one or more macromolecules, wherein the spatial distribution of one or more solutes or water is used to identify preferential affinity of each of the solutes or water to each of the one or more macromolecules, and wherein said one or more macromolecules are selected from a protein, RNA, DNA, carbohydrate, lipid, organic chemical, inorganic chemical, or a combination thereof. 1) assigning a target concentration, N tgt, of each of the one or more solutes and water; 2) sampling the spatial distribution of the one or more solutes and water in a computationally defined region of space using Grand-Canonical Monte-Carlo (GCMC) Metropolis sampling criteria, wherein the excess chemical potential (μ ex) assigned for each of the one or more solutes, if present, and water is set to 0, if present; 3) updating μ ex of each of the one or more solutes and water from the difference in current concentration in the defined region of space (N sys) and the target (N tgt); 4) repeating steps 2) and 3) using the updated values of μ ex in step 2) to obtain a spatial distribution of the one or more solutes and water;
A skirt member (20, 120) for use in a flashing for a roof penetrating structure, comprising a first edge (31, 131) intended to be arranged at the roof penetrating structure, a second edge (32, 132) opposite the first edge (31, 131) and intended to rest on a roof surface and two end edges extending between the first and second edges, and comprising a first cover layer (21, 121) and a second cover layer (23, 123), said first and second cover layers being interconnected by a first adhesive layer (22, 122), said first cover layer (21, 121) being intended to face the exterior of a building in the mounted state of the flashing, and wherein it further comprises a second adhesive layer (24, 124) interconnecting a third cover layer (25, 125) to the second cover layer (23, 123), wherein the second cover layer (23, 123) being made of a sheet material or nonwoven made of a polymer, characterized in that said first adhesive layer (22,122) having a density of at least 2.5 g/ml, and that said first adhesive layer (22, 122) comprises a non-structural constituent in the form of a metal compound and said second adhesive layer (24, 124) is made from material without metal particles.
A height adjustable wheelchair docking system adapted for releasably securing a wheelchair to the floor of a transport vehicle comprising: - a base frame with two side walls, and an open end, said base frame adapted for rigid attachment to the floor of a transport vehicle; - a middle frame with two side walls, said middle frame adapted for sliding back and forth in a horizontal direction within said base frame and through said open end; - means configured to slide said middle frame in relation to said base frame; and - a top frame with two side walls, the top frame adapted for covering at least a part of said base frame and middle frame, and adapted to move up and down in a vertical direction in relation to said base frame when said middle frame is sliding back and forth in a horizontal direction within said base frame and through the open end; wherein said top frame further comprises a female or male docking fixture adapted for locking engagement with a male or female docking fixture on a wheelchair; wherein said base frame and said middle frame each comprises one member of a pair of oppositely angled guide tracks (210, 320) in their side wall (204, 304); wherein said top frame comprises a channel in its side wall; wherein the pair of oppositely angled guide tracks (210, 320) and said channel together form a channel in which a guide pin is positioned. - a base frame with two side walls, and an open end, said base frame adapted for rigid attachment to the floor of a transport vehicle; - a middle frame with two side walls, said middle frame adapted for sliding back and forth in a horizontal direction within said base frame and through said open end; - means configured to slide said middle frame in relation to said base frame; and - a top frame with two side walls, the top frame adapted for covering at least a part of said base frame and middle frame, and adapted to move up and down in a vertical direction in relation to said base frame when said middle frame is sliding back and forth in a horizontal direction within said base frame and through the open end; wherein said top frame further comprises a female or male docking fixture adapted for locking engagement with a male or female docking fixture on a wheelchair;
A polymerization initiator comprising one or more compounds selected from the group consisting of a pyrazolidinedione compound and/or pyrazolidine(di)thione compound, and a salt of the compound, and a transition metal compound.
Polyesters obtained from alpha-epoxides that are derived from alpha-olefins comprising 10 to 16 carbon atoms, or from diols that are derived from that alpha-epoxides, and saturated linear aliphatic dicarboxylic acids selected from the group consisting of azelaic acid (nonanedioic acid), sebacic acid (decanedioic acid), dodecanedioic acid and mixtures thereof, wherein the polyesters have a number-average molecular weight M n in the range of 1,000 to 15,000 g/mol, determined by size exclusion chromatography using polymethylmethacrylate standards.
A method for rotary pressure cutting a moving source material including rotating a cutting cylinder about its longitudinal axis, wherein said cutting cylinder includes a lateral peripheral portion and a cutting blade extending outwardly from said lateral peripheral portion; positioning a structural member adjacent to, and in spaced relation from, said cutting cylinder, wherein the space between said cutting cylinder and said structural member is adapted to receive the moving source material, positioning an anvil in the space between said cutting cylinder and said structural member, wherein said anvil is adapted to engage and support the moving source material when the source material is displaced between said cutting cylinder and said structural member, directing the rotating cylinder's cutting blade into contact with the moving source material, whereupon said moving source material is pressed against said anvil and is severed by said cutting blade, and said anvil is displaced by said cutting blade from a first retracted position to a second activated position, applying an increasing biasing force to said moving anvil as it is displaced toward said second activated position so as to reverse the movement of said anvil and direct the anvil back to its first retracted position, wherein said biasing force is produced by increasingly bending each of a pair of flexible, resilient members coupled to said anvil as said anvil approaches said second activated position, whereupon release of deflection of said pair of flexible, resilient members causes said flexible, resilient members to return said anvil to said first retracted position in preparation for the next cut of the moving source material, the method characterized by coupling said anvil to each of said flexible resilient members by means of a respective semispherical ball bearing arrangement for reduced mass and increased reciprocating speeds of said anvil, wherein each semispherical ball bearing arrangement includes a pair of coupled upper and lower generally semispherical rotatable members coupled to first and second opposed portions of said anvil, respectively, with each semispherical ball bearing arrangement further including at least one inner ball bearing coupled to said upper and lower semispherical rotatable members, and wherein said flexible members include an upper spring member and a lower spring member respectively engaging said upper and lower semispherical rotatable member.
Use of cyclohexa-2,5-dien-1-yl-silanes of general formula wherein R 1 and R 2 represent independently from each other C 1 -C 3 -alkyl or C 1 -C 3 -alkoxy, R 3 represent independently from R 1 and R 2 H, C 1 -C 3 -alkyl, C 1 -C 3 -alkoxy or aryl and R 4 and R 5 represent independently from each other H, C 1 -C 3 -alkyl or R 1 R 2 R 3 Si with R 1 to R 3 as defined above, and a Lewis acid of general formulae II or IIa B(C 6 F m H n) 3 wherein m+n=5, m = 0 to 5 and n = 0 to 5, BF 3 ·O 2 (IIa) wherein R is methyl or ethyl, for hydrosilylation of alkenes and carbonyl compounds under concomitant formation of an arene solvent. R 1 and R 2 represent independently from each other C 1 -C 3 -alkyl or C 1 -C 3 -alkoxy, R 3 represent independently from R 1 and R 2 H, C 1 -C 3 -alkyl, C 1 -C 3 -alkoxy or aryl and R 4 and R 5 represent independently from each other H, C 1 -C 3 -alkyl or R 1 R 2 R 3 Si with R 1 to R 3 as defined above, and a Lewis acid of general formulae II or IIa B(C 6 F m H n) 3 wherein m+n=5, m = 0 to 5 and n = 0 to 5, BF 3 ·O 2 (IIa) wherein R is methyl or ethyl, for hydrosilylation of alkenes and carbonyl compounds under concomitant formation of an arene solvent.
A method of predicting the response of a subject having, suspected of having, or at risk of developing, a thyroid cancer or a kidney cancer to a therapy comprising lenvatinib or a pharmaceutically acceptable salt thereof, the method comprising: providing a biological sample obtained from the subject after the therapy comprising lenvatinib or a pharmaceutically acceptable salt thereof; and measuring the concentration of ANGPT2 protein in the biological sample, wherein a reduced concentration, as compared to a control, of ANGPT2 is predictive that the subject will respond to the therapy comprising lenvatinib or a pharmaceutically acceptable salt thereof. providing a biological sample obtained from the subject after the therapy comprising lenvatinib or a pharmaceutically acceptable salt thereof; and measuring the concentration of ANGPT2 protein in the biological sample, wherein a reduced concentration, as compared to a control, of ANGPT2 is predictive that the subject will respond to the therapy comprising lenvatinib or a pharmaceutically acceptable salt thereof.
Data carrier made of cellulosic materials or of plastic intended to be handled relatively frequently, characterized in that it contains at least one bacteriostatic and/or bactericidal agent, and at least one fungistatic and/or fungicidal agent, and containing silver ions as the bacteriostatic and/or bactericidal agent, and an agent based on p-[(diiodomethyl)sulfonyl] toluene in the form of aqueous dispersion or an agent based on iodopropynyl butylcarbamate in the form of aqueous dispersion as the fungistatic and/or fungicidal agent.
A system for ventilating a vacuum bandage covering a wound having a wound surface, and the bandage being connectable to a vacuum source and an irrigation source, the system comprising: a multi-lumen tube configured to couple to the vacuum bandage, the multi-lumen tube including a first lumen configured to communicate with the vacuum source, a second lumen in communication with the surrounding atmosphere, and a third lumen in communication with the irrigation source, a wound dressing member coupled to the multi-lumen tube, the wound dressing member being provided to communicate negative pressure from the vacuum source to the wound, a vent coupled to the multi-lumen tube and including a passageway between the second lumen and the surrounding atmosphere wherein the vent includes a multi-lumen connector coupled to the multi-lumen tube and a single-lumen connector configured to be coupled to the vacuum source, wherein the vent further includes another single-lumen connector configured to be coupled to the irrigation source, wherein the multi-lumen connector includes an irrigation conduit coupled to the single-lumen connector configured to be coupled to the irrigation source and a vacuum conduit coupled to the single-lumen connector configured to be coupled to the vacuum source; wherein the multi-lumen connector further includes an outer conduit positioned around and spaced-apart from the vacuum and irrigation conduits (274, 276) to create a space in communication with the second lumen and with the surrounding atmosphere. a multi-lumen tube configured to couple to the vacuum bandage, the multi-lumen tube including a first lumen configured to communicate with the vacuum source, a second lumen in communication with the surrounding atmosphere, and a third lumen in communication with the irrigation source, a wound dressing member coupled to the multi-lumen tube, the wound dressing member being provided to communicate negative pressure from the vacuum source to the wound, a vent coupled to the multi-lumen tube and including a passageway between the second lumen and the surrounding atmosphere wherein the vent includes a multi-lumen connector coupled to the multi-lumen tube and a single-lumen connector configured to be coupled to the vacuum source, wherein the vent further includes another single-lumen connector configured to be coupled to the irrigation source, wherein the multi-lumen connector includes an irrigation conduit coupled to the single-lumen connector configured to be coupled to the irrigation source and a vacuum conduit coupled to the single-lumen connector configured to be coupled to the vacuum source; wherein the multi-lumen connector further includes an outer conduit positioned around and spaced-apart from the vacuum and irrigation conduits (274, 276) to create a space in communication with the second lumen and with the surrounding atmosphere.
A medical system, comprising: an insertion device having: a handle; a shaft coupled to the handle of the insertion device; and a port positioned on the handle of the insertion device and in fluid communication with a working channel of the shaft, the port comprising a female luer port; a medical device having: an elongate control member terminating in an end effector; and a handle having a plurality of circumferential slots along the length of the handle; and a plunger moveable along a longitudinal axis of the handle of the medical device between a first position and a second position; wherein in the first position, the end effector is positioned within the shaft, and wherein in the second position, the end effector is positioned distally of the shaft, characterised in that the handle of the insertion device includes a clip on a proximal end thereof, the clip including a plurality of arms (172, 174) defining a receiving space for receiving the handle of the medical device therebetween, such that an operator may hold both the handle of the insertion device and the handle of the medical device in a single hand. an insertion device having: a handle; a shaft coupled to the handle of the insertion device; and a port positioned on the handle of the insertion device and in fluid communication with a working channel of the shaft, the port comprising a female luer port; a handle; a shaft coupled to the handle of the insertion device; and a port positioned on the handle of the insertion device and in fluid communication with a working channel of the shaft, the port comprising a female luer port; a medical device having: an elongate control member terminating in an end effector; and a handle having a plurality of circumferential slots along the length of the handle; and a plunger moveable along a longitudinal axis of the handle of the medical device between a first position and a second position; an elongate control member terminating in an end effector; and a handle having a plurality of circumferential slots along the length of the handle; and a plunger moveable along a longitudinal axis of the handle of the medical device between a first position and a second position; wherein in the first position, the end effector is positioned within the shaft, and wherein in the second position, the end effector is positioned distally of the shaft, characterised in that the handle of the insertion device includes a clip on a proximal end thereof, the clip including a plurality of arms (172, 174) defining a receiving space for receiving the handle of the medical device therebetween, such that an operator may hold both the handle of the insertion device and the handle of the medical device in a single hand.
A heat-treated carbon black prepared by a process comprising heating a carbon black at a temperature ranging from 1100°C to 1700°C in an inert atmosphere to form the heat-treated carbon black, wherein the heat-treated carbon black has a Brunauer-Emmett-Teller surface area ranging from 100 m 2 /g to 1100 m 2 /g and a) a surface energy of 10 mJ/m 2 or less and/or b) a Raman microcrystalline planar size (L a) ranging from 2.2 nm to 5 nm (22 Å to 50 Å). a) a surface energy of 10 mJ/m 2 or less and/or b) a Raman microcrystalline planar size (L a) ranging from 2.2 nm to 5 nm (22 Å to 50 Å).
Sputtering target consisting of a NiSi alloy consisting of Ni, from 2 to 8 weight% Si, optionally dopant elements in an amount of 1000 ppm or less, and the remainder being unavoidable impurities, characterized in that the NiSi alloy has an average grain size of 150 to 400 μm and a grain size variation of lower than 30% both measured according to the specification.
An airbag module for a steering wheel, comprising fastening means and further comprising a gas generator support that interconnects a gas generator with a covering, said gas generator support being fastened to said gas generator and said covering, wherein said gas generator support comprises an airbag fabric characterized in that said gas generator comprises a flange-type extension which is fastened to an inner circumference defined by an inner opening of the gas generator support together with a free end of a folded air bag via said fastening means, said fastening means being adapted to be fastened to said steering wheel.
An isolated antibody, or antigen binding portion thereof, that specifically binds to human CD40, wherein said antibody comprises a heavy chain, and a light chain, wherein: said heavy chain comprises a CDR1 comprising GYTFTDLSMHW (SEQ ID NO: 1), a CDR2 comprising YITPSSGYTAYNQKFKG (SEQ ID NO: 2), a CDR3 comprising LILQRGAY (SEQ ID NO: 3) and a human heavy chain constant region; and said light chain comprises a CDR1 comprising RASKNVDSYGNSFMHW (SEQ ID NO: 4), a CDR2 comprising RASNLES (SEQ ID NO: 5), a CDR3 comprising QQSNEDPLT (SEQ ID NO: 6) and a human light chain constant region, and said human heavy chain constant region is a human IgG1 Fc domain comprising a mutation at Kabat position 238 that reduces binding to Fc-gamma-receptors (FcgRs), wherein proline 238 is mutated to lysine or arginine, and wherein the antibody or antigen binding portion has reduced FcgR binding. said heavy chain comprises a CDR1 comprising GYTFTDLSMHW (SEQ ID NO: 1), a CDR2 comprising YITPSSGYTAYNQKFKG (SEQ ID NO: 2), a CDR3 comprising LILQRGAY (SEQ ID NO: 3) and a human heavy chain constant region; and said light chain comprises a CDR1 comprising RASKNVDSYGNSFMHW (SEQ ID NO: 4), a CDR2 comprising RASNLES (SEQ ID NO: 5), a CDR3 comprising QQSNEDPLT (SEQ ID NO: 6) and a human light chain constant region, and said human heavy chain constant region is a human IgG1 Fc domain comprising a mutation at Kabat position 238 that reduces binding to Fc-gamma-receptors (FcgRs), wherein proline 238 is mutated to lysine or arginine, and wherein the antibody or antigen binding portion has reduced FcgR binding.
A method for producing acetic acid comprising: A) combining, in a carbonylation reactor, a carbonylation catalyst, methanol, carbon monoxide, and water, to form a reactor mixture; B) introducing a feed stream comprising methyl acetate and methanol into the carbonylation reactor, and C) measuring a concentration of methyl acetate and/or methanol in the feed stream by Raman spectroscopic analysis or by infrared spectroscopic analysis; and D) adjusting at least one feed stream comprising water in response to the concentration measured by Raman spectroscopic analysis or infrared spectroscopic analysis. A) combining, in a carbonylation reactor, a carbonylation catalyst, methanol, carbon monoxide, and water, to form a reactor mixture; B) introducing a feed stream comprising methyl acetate and methanol into the carbonylation reactor, and C) measuring a concentration of methyl acetate and/or methanol in the feed stream by Raman spectroscopic analysis or by infrared spectroscopic analysis; and D) adjusting at least one feed stream comprising water in response to the concentration measured by Raman spectroscopic analysis or infrared spectroscopic analysis.