A method, in a controlling device in wireless telecommunication networks, of controlling the cancellation of the interference among received signals of multiple mobile stations (MS2, MS2', MS2") in a macro-diversity handover zone dominated by the controlling device, comprising: a. obtaining channel related information of the downlinks between multiple mobile stations (MS2, MS2', MS2") in said macro-diversity handover zone and multiple base stations (BS1, BS1', BS1") that serve said macro-diversity handover zone; b. selecting, based on said channel related information, multiple base stations (BS1, BS1', BS1") from said multiple base stations (BS1, BS1', BS1") that serve said macro-diversity handover zone for jointly sending downlink signals to said multiple mobile stations (MS2, MS2', MS2"), over same time-frequency resources; grouping said multiple base stations (BS1, BS1', BS1") that serve said macro-diversity handover zone into multiple base station groups and grouping said multiple mobile stations (MS2, MS2', MS2") into multiple mobile station groups based on said channel related information, wherein base stations (BS1, BS1', BS1") of each group jointly send downlink signals to corresponding one mobile station group over same time-frequency resources respectively, and said time frequency resources occupied by each base station group is different c. determining precoding coefficients of said multiple base stations (BS1, BS1', BS1") based on said channel related information and a predetermined rule, said precoding coefficients configured to be used by said multiple base stations (BS1, BS1', BS1") to precode the multi-streams modulated signals to be sent jointly by said multiple base stations (BS1, BS1', BS1") to said multiple mobile stations (MS2, MS2', MS2") over same time-frequency resources, so as to cancel interference among received signals of said multiple mobile stations (MS2, MS2', MS2"); determining precoding coefficients of said selected multiple base stations (BS1, BS1', BS1"), based on channel related information between said selected multiple base stations (BS1, BS1', BS1") and said multiple mobile stations (MS2, MS2', MS2") and said predetermined rule; determining precoding coefficients of multiple base stations (BS1, BS1', BS1") of each group based on said channel related information and said predetermined rule, said precoding coefficients configured to be used by said multiple base stations (BS1, BS1', BS1") of said each group to precode the modulated signals to be sent jointly over same time-frequency resources to a corresponding group of multiple mobile stations (MS2, MS2', MS2"). d. informing each base station of its corresponding precoding coefficients. a. obtaining channel related information of the downlinks between multiple mobile stations (MS2, MS2', MS2") in said macro-diversity handover zone and multiple base stations (BS1, BS1', BS1") that serve said macro-diversity handover zone; b. selecting, based on said channel related information, multiple base stations (BS1, BS1', BS1") from said multiple base stations (BS1, BS1', BS1") that serve said macro-diversity handover zone for jointly sending downlink signals to said multiple mobile stations (MS2, MS2', MS2"), over same time-frequency resources; grouping said multiple base stations (BS1, BS1', BS1") that serve said macro-diversity handover zone into multiple base station groups and grouping said multiple mobile stations (MS2, MS2', MS2") into multiple mobile station groups based on said channel related information, wherein base stations (BS1, BS1', BS1") of each group jointly send downlink signals to corresponding one mobile station group over same time-frequency resources respectively, and said time frequency resources occupied by each base station group is different c. determining precoding coefficients of said multiple base stations (BS1, BS1', BS1") based on said channel related information and a predetermined rule, said precoding coefficients configured to be used by said multiple base stations (BS1, BS1', BS1") to precode the multi-streams modulated signals to be sent jointly by said multiple base stations (BS1, BS1', BS1") to said multiple mobile stations (MS2, MS2', MS2") over same time-frequency resources, so as to cancel interference among received signals of said multiple mobile stations (MS2, MS2', MS2"); determining precoding coefficients of said selected multiple base stations (BS1, BS1', BS1"), based on channel related information between said selected multiple base stations (BS1, BS1', BS1") and said multiple mobile stations (MS2, MS2', MS2") and said predetermined rule; determining precoding coefficients of multiple base stations (BS1, BS1', BS1") of each group based on said channel related information and said predetermined rule, said precoding coefficients configured to be used by said multiple base stations (BS1, BS1', BS1") of said each group to precode the modulated signals to be sent jointly over same time-frequency resources to a corresponding group of multiple mobile stations (MS2, MS2', MS2"). d. informing each base station of its corresponding precoding coefficients.