A device for targeted and individualized delivery of multiple skin benefit agents to the skin of a user comprising: a first device for capturing an image of a predetermined treatment area of the user's skin; means for analyzing the image captured with the first device for mapping the predetermined treatment area; a second device for capturing selective data inputs, wherein the second device is an input device for diagnosing skin conditions in the predetermined treatment area, the input device selected from at least of a digital imaging device, a spectral camera system, a thermal camera system, a laser Doppler imaging system, a translucency meter, a skin pH meter, a moisture meter, an elasticity meter, a scope camera, a keyboard and a touch screen; means for generating from the captured selective data inputs a skin profile indicative of the conditions of the predetermined treatment area of the user's skin; means for processing the captured image, the mapping and the skin profile to generate a virtual 3D image of the user's face or head to allow more precise location of treatment areas, the 3D image showing the conditions of the predetermined treatment area; and means for generating a cosmetically active product for targeted and individualized delivery of multiple skin benefit agents based on the generated skin profile, wherein the product contains different skin benefit agents for treating the indicated conditions of the predetermined treatment area, and wherein said product is a cosmetic delivery sheet arranged and constructed for conforming to the predetermined treatment area of the user's skin, and wherein said cosmetic delivery sheet comprises a substrate with multiple isolate, discrete regions, wherein at least two of the isolate, discrete regions are imprinted with different skin benefit agents for treating different skin conditions of the predetermined treatment area. a first device for capturing an image of a predetermined treatment area of the user's skin; means for analyzing the image captured with the first device for mapping the predetermined treatment area; a second device for capturing selective data inputs, wherein the second device is an input device for diagnosing skin conditions in the predetermined treatment area, the input device selected from at least of a digital imaging device, a spectral camera system, a thermal camera system, a laser Doppler imaging system, a translucency meter, a skin pH meter, a moisture meter, an elasticity meter, a scope camera, a keyboard and a touch screen; means for generating from the captured selective data inputs a skin profile indicative of the conditions of the predetermined treatment area of the user's skin; means for processing the captured image, the mapping and the skin profile to generate a virtual 3D image of the user's face or head to allow more precise location of treatment areas, the 3D image showing the conditions of the predetermined treatment area; and means for generating a cosmetically active product for targeted and individualized delivery of multiple skin benefit agents based on the generated skin profile, wherein the product contains different skin benefit agents for treating the indicated conditions of the predetermined treatment area, and wherein said product is a cosmetic delivery sheet arranged and constructed for conforming to the predetermined treatment area of the user's skin, and wherein said cosmetic delivery sheet comprises a substrate with multiple isolate, discrete regions, wherein at least two of the isolate, discrete regions are imprinted with different skin benefit agents for treating different skin conditions of the predetermined treatment area.