A solid oral dosage form, which is a tablet or capsule, comprising: a core comprising a compound chosen from: and/or a pharmaceutically acceptable salt thereof; an enteric coating; a subcoat between the enteric coating and the core, wherein the subcoat is: a water soluble or hydrophilic erodible polymer, said polymer being a low molecular weight polymer selected from hydroxymethyl cellulose (HPMC), hydroxyethyl cellulose, hydroxymethyl cellulose, hydroxypropyl cellulose, microcrystalline cellulose, polyvinylpyrrolidiones, polysaccharides (or a polysaccharide derivative), polyvinyl alcohols, polyethylene glycol, polypropylene glycol, and PEG-PPG block copolymers; or a water insoluble composition comprising: (i) particles of a water soluble compound capable of forming channels in the water insoluble composition; or (ii) water insoluble hydrophilic particles which cause swelling of the subcoat when in contact with an aqueous media; and a pharmaceutically acceptable excipient, wherein the solid oral dosage form has an onset of release of the compound and/or said pharmaceutically acceptable salt thereof of the core into the ileo-jejunal portion of the small intestine of a mammal after oral ingestion of the dosage form by the mammal; and wherein the solid oral dosage form is able to release at least 80% by weight of said compound and/or said pharmaceutically acceptable salt thereof in 120 minutes in a dissolution vessel comprising an aqueous solution at a pH of from 6.4 to 7.4. a core comprising a compound chosen from: and/or a pharmaceutically acceptable salt thereof; an enteric coating; a subcoat between the enteric coating and the core, wherein the subcoat is: a water soluble or hydrophilic erodible polymer, said polymer being a low molecular weight polymer selected from hydroxymethyl cellulose (HPMC), hydroxyethyl cellulose, hydroxymethyl cellulose, hydroxypropyl cellulose, microcrystalline cellulose, polyvinylpyrrolidiones, polysaccharides (or a polysaccharide derivative), polyvinyl alcohols, polyethylene glycol, polypropylene glycol, and PEG-PPG block copolymers; or a water insoluble composition comprising: (i) particles of a water soluble compound capable of forming channels in the water insoluble composition; or (ii) water insoluble hydrophilic particles which cause swelling of the subcoat when in contact with an aqueous media; and a water soluble or hydrophilic erodible polymer, said polymer being a low molecular weight polymer selected from hydroxymethyl cellulose (HPMC), hydroxyethyl cellulose, hydroxymethyl cellulose, hydroxypropyl cellulose, microcrystalline cellulose, polyvinylpyrrolidiones, polysaccharides (or a polysaccharide derivative), polyvinyl alcohols, polyethylene glycol, polypropylene glycol, and PEG-PPG block copolymers; or a water insoluble composition comprising: (i) particles of a water soluble compound capable of forming channels in the water insoluble composition; or (ii) water insoluble hydrophilic particles which cause swelling of the subcoat when in contact with an aqueous media; and a pharmaceutically acceptable excipient, wherein the solid oral dosage form has an onset of release of the compound and/or said pharmaceutically acceptable salt thereof of the core into the ileo-jejunal portion of the small intestine of a mammal after oral ingestion of the dosage form by the mammal; and wherein the solid oral dosage form is able to release at least 80% by weight of said compound and/or said pharmaceutically acceptable salt thereof in 120 minutes in a dissolution vessel comprising an aqueous solution at a pH of from 6.4 to 7.4. wherein the solid oral dosage form has an onset of release of the compound and/or said pharmaceutically acceptable salt thereof of the core into the ileo-jejunal portion of the small intestine of a mammal after oral ingestion of the dosage form by the mammal; and wherein the solid oral dosage form is able to release at least 80% by weight of said compound and/or said pharmaceutically acceptable salt thereof in 120 minutes in a dissolution vessel comprising an aqueous solution at a pH of from 6.4 to 7.4.