mhurhangee/ep-ind-claims huggingface dataset:
A kit for sequencing a polynucleotide target, comprising: (a) two amplification primers for amplifying DNA by a polymerase chain reaction process, one that is complementary to a first locus on one strand of the DNA, and a second that is complementary to a different or second locus of the other strand of the DNA, said amplification primers each comprising (i) a 3' target-specific nucleotide sequence and (ii) a 5' non-target-specific universal sequencing tag comprising at least three contiguous non-natural nucleobases capable of complementary binding to a corresponding non-natural nucleobase, wherein at least three contiguous non-natural nucleobases are capable of being replicated during amplification by an amplification polymerase but are not capable of being sequenced by a sequencing polymerase, whereby the portion of (ii) that is 5' to the at least three contiguous non-natural nucleobases cannot be sequenced; and (b) corresponding universal sequencing primers each comprising an oligonucleotide of the sequence comprising the 5' non-target-specific universal sequencing tag of the corresponding amplification primer, wherein the tag comprises at least three contiguous non-natural nucleobase capable of hybridizing to complementary non-natural nucleobases and capable of being replicated during amplification. (a) two amplification primers for amplifying DNA by a polymerase chain reaction process, one that is complementary to a first locus on one strand of the DNA, and a second that is complementary to a different or second locus of the other strand of the DNA, said amplification primers each comprising (i) a 3' target-specific nucleotide sequence and (ii) a 5' non-target-specific universal sequencing tag comprising at least three contiguous non-natural nucleobases capable of complementary binding to a corresponding non-natural nucleobase, wherein at least three contiguous non-natural nucleobases are capable of being replicated during amplification by an amplification polymerase but are not capable of being sequenced by a sequencing polymerase, whereby the portion of (ii) that is 5' to the at least three contiguous non-natural nucleobases cannot be sequenced; and (i) a 3' target-specific nucleotide sequence and (ii) a 5' non-target-specific universal sequencing tag comprising (b) corresponding universal sequencing primers each comprising an oligonucleotide of the sequence comprising the 5' non-target-specific universal sequencing tag of the corresponding amplification primer, wherein the tag comprises at least three contiguous non-natural nucleobase capable of hybridizing to complementary non-natural nucleobases and capable of being replicated during amplification.
An unlicensed channel sharing method, comprising: determining a channel sharing information, wherein the channel sharing information comprises a slot format information of Channel Occupy Time, COT, that is available for a network to access and occupy an unlicensed channel; and sending the channel sharing information to the network, wherein the slot format information comprises a slot deviation, where the slot deviation refers to a number of slots between a slot in which the channel sharing information is carried and a starting slot of the COT. determining a channel sharing information, wherein the channel sharing information comprises a slot format information of Channel Occupy Time, COT, that is available for a network to access and occupy an unlicensed channel; and sending the channel sharing information to the network, wherein the slot format information comprises a slot deviation, where the slot deviation refers to a number of slots between a slot in which the channel sharing information is carried and a starting slot of the COT.
Non-aqueous pigment concentrate comprising one or more pigments, one or more dispersants, and at least one resin, characterized in that the resin is a polyester comprising on average 2 to 7 oligo-ester building blocks with a hydrophobic tail linked thereto, wherein the hydrophobic tail is selected from the group consisting of: - branched hydrocarbons, - hydrocarbons containing a cyclic group, and - linear hydrocarbons, provided that when said linear hydrocarbon is linked to the oligo-ester building block via an ester group, the linear hydrocarbon contains 3 to 12 carbon atoms, and wherein the polyester is formed by reacting one or more anhydrides and/or the corresponding dicarboxylic: acids with one or more diols and/or monoepoxides having said pendent hydrophobic tail, and a monofunctional starter molecule selected from the group of alcohols, amines, carboxylic acids, or thiols. - branched hydrocarbons, - hydrocarbons containing a cyclic group, and - linear hydrocarbons, provided that when said linear hydrocarbon is linked to the oligo-ester building block via an ester group, the linear hydrocarbon contains 3 to 12 carbon atoms,
Wheelbarrow for the spreading of a material comprising a bucket intended to contain at least one material, said bucket comprising a base wall, a front wall, a rear wall, two side walls (30, 30'), a first upper opening, characterised in that it comprises a second opening in said base wall and/or the front wall through which the material is intended to flow, a closing flap closing the second opening and means for controlling the opening of said closing flap, the wheelbarrow comprises a distribution plate which is a generally rectangular shape and extends longitudinally according to a longitudinal axis parallel to a transverse axis of the wheelbarrow, under the whole length of the second opening, said plate being positioned under the second opening so that when a material flows gravitationally through the opening, said material flows over the plate along its surface across its width towards a surface requiring the application under the wheelbarrow or in front of the wheelbarrow.
A method of determining risk of experiencing a major adverse cardiac event (MACE), in a patient, within one year from presentation of at least one symptom of acute coronary syndrome comprising the steps of: a) determining the amount in a test sample from said patient of at least three biomarkers selected from the group consisting of BNP, P1GF, eGFR and homocysteine; or from the group consisting of BNP, P1GF and eGFR; or from the group consisting of cTnI, BNP and P1GF; or from the group consisting of cTnI, BNP, choline and eGFR in said test sample; and b) comparing the amount of said at least three biomarkers to biomarker reference standards, wherein said risk is determined by results of said comparison, wherein the biomarker reference standard is 150 pg/mL for BNP, 20 pg/mL for P1GF, 68 mL/min/1.73 m 2 for EGFR, 12.5 μmol/L for homocysteine, 49 μmol/L for choline, and 0.015 ng/mL for cTnI. a) determining the amount in a test sample from said patient of at least three biomarkers selected from the group consisting of BNP, P1GF, eGFR and homocysteine; or from the group consisting of BNP, P1GF and eGFR; or from the group consisting of cTnI, BNP and P1GF; or from the group consisting of cTnI, BNP, choline and eGFR in said test sample; and b) comparing the amount of said at least three biomarkers to biomarker reference standards, wherein said risk is determined by results of said comparison, wherein the biomarker reference standard is 150 pg/mL for BNP, 20 pg/mL for P1GF, 68 mL/min/1.73 m 2 for EGFR, 12.5 μmol/L for homocysteine, 49 μmol/L for choline, and 0.015 ng/mL for cTnI.
A resin composition comprising 100 parts by weight of an organic resin and 50 to 1,000 parts by weight of an inorganic filler, wherein 10 to 100% by weight of the inorganic filler is composed of an oxide of a rare earth element selected from yttrium, neodymium, lanthanum, cerium, samarium, gadolinium or dysprosium.
Electronic device for a firearm having a grip comprising: a) a firearm element, configured to detect and/or manage one or more events occurring to the firearm, including an event of a shot fired, housable in a housing in the grip of the firearm, wherein the firearm element comprises a power supply battery and comprises a firearm interface port for access to said power supply battery, wherein the firearm interface port comprises at least one firearm pin flat or convex in such a way that is flush or convex with respect to the firearm, when the firearm element is housed in the grip of the firearm; b) a base element engageable to the grip, for example housed in a firearm base, comprising a base interface port that comprises at least one base pin, wherein the base pin has a substantially complementary shape of the respective firearm pin, wherein the base element comprises a main port electrically connected with the base interface port, wherein the main port is configured to be operatively connected to a source of electricity, to provide electrical power to the base element, wherein the base pin further comprises elastic elements suitable to allow correct alignment between the at least one firearm pin and the at least one base pin; wherein, in the reciprocal engagement between the firearm element and the base element through the at least one firearm pin and the respective at least base pin, the base element is configured to electrically recharge the power supply battery. a) a firearm element, configured to detect and/or manage one or more events occurring to the firearm, including an event of a shot fired, housable in a housing in the grip of the firearm, wherein the firearm element comprises a power supply battery and comprises a firearm interface port for access to said power supply battery, wherein the firearm interface port comprises at least one firearm pin flat or convex in such a way that is flush or convex with respect to the firearm, when the firearm element is housed in the grip of the firearm; b) a base element engageable to the grip, for example housed in a firearm base, comprising a base interface port that comprises at least one base pin, wherein the base pin has a substantially complementary shape of the respective firearm pin, wherein the base element comprises a main port electrically connected with the base interface port, wherein the main port is configured to be operatively connected to a source of electricity, to provide electrical power to the base element, wherein the base pin further comprises elastic elements suitable to allow correct alignment between the at least one firearm pin and the at least one base pin;
Method performed by a User Equipment, UE, for determining separate channel state information, CSI, for a flexible subframe in a wireless communication system applying time division duplex, TDD, the method comprising: for a scheduled downlink flexible subframe: - receiving a signal from a base station; - determining (104, 204) whether a reference signal for CSI measurement is comprised in the received signal; - determining (106, 206, 403) CSI for the flexible subframe based on the reference signal when a reference signal for CSI measurement is comprised in the received signal; and - reporting (107, 207) the determined CSI to the base station, wherein the determined CSI is reported to the base station in one or more configured uplink resources until at least one of the following is fulfilled: - a predefined time period has elapsed after the determining of the CSI; - the CSI has been reported a predefined number of times; and - a more recent CSI for a flexible subframe is determined. - receiving a signal from a base station; - determining (104, 204) whether a reference signal for CSI measurement is comprised in the received signal; - determining (106, 206, 403) CSI for the flexible subframe based on the reference signal when a reference signal for CSI measurement is comprised in the received signal; and - reporting (107, 207) the determined CSI to the base station, - a predefined time period has elapsed after the determining of the CSI; - the CSI has been reported a predefined number of times; and - a more recent CSI for a flexible subframe is determined.
A laser processing method comprising: irradiating laser lights (Ls) of fiber lasers or direct diode lasers from a nozzle to an iron-based plate material; selecting a nozzle to be used that has a nozzle opening (2b2) with an opening diameter preliminarily set according to a thickness (t) of the plate material to be worked and with respect to each output power of the laser lights (Ls) from a plurality of nozzles whose nozzle openings (2b2) have different opening diameters from each other; cutting the plate material by injecting assist gas from the nozzle opening (2b2) while irradiating the laser lights (Ls) onto the plate material, characterized in that a trial cutting is performed in advance to grasp the opening diameter which enables good cutting for each of different plate thicknesses (t) and each output power of the laser lights (Ls), and a nozzle selection table (Tn) is created in advance; the nozzle having the nozzle diameter associated with the thickness (t) of the plate material to be cut and with respect to the desired output power of the laser lights (Ls) is selected with respect to said nozzle selection table (Tn), and the plate material is cut with said nozzle. irradiating laser lights (Ls) of fiber lasers or direct diode lasers from a nozzle to an iron-based plate material; selecting a nozzle to be used that has a nozzle opening (2b2) with an opening diameter preliminarily set according to a thickness (t) of the plate material to be worked and with respect to each output power of the laser lights (Ls) from a plurality of nozzles whose nozzle openings (2b2) have different opening diameters from each other; cutting the plate material by injecting assist gas from the nozzle opening (2b2) while irradiating the laser lights (Ls) onto the plate material, characterized in that a trial cutting is performed in advance to grasp the opening diameter which enables good cutting for each of different plate thicknesses (t) and each output power of the laser lights (Ls), and a nozzle selection table (Tn) is created in advance; the nozzle having the nozzle diameter associated with the thickness (t) of the plate material to be cut and with respect to the desired output power of the laser lights (Ls) is selected with respect to said nozzle selection table (Tn), and the plate material is cut with said nozzle.
An aerosol generating article, the aerosol generating article comprising an aerosolisable material and a wrapper wrapped around the aerosolisable material, wherein the wrapper comprises at least three layers; an innermost peripheral layer disposed in contact with the aerosolisable material and an outermost peripheral layer, the innermost and outermost peripheral layers (501, 503) comprising paper, and an intermediate layer comprising a non-combustible material, wherein at least the intermediate layer and one of the innermost or outermost peripheral layers (501, 503) are provided as a laminate structure, characterised in that the paper of either or each of the innermost and outermost layers (501, 503) has a basis weight of 25 to 50 g/m 2 and in that the wrapper extends from a distal end of the aerosol generating article.
A column structure for the containment of high surface area packing and absorbent liquid reagent for the removal of a target gas from a gas stream comprising a plurality of vessel column modules each having an elongate upright vessel wall structure defining a perimeter comprising a closed simple polygon or closed simple curve or combination of the same that surrounds a process volume within the column module, the column modules being disposed together alongside one another in two dimensional array to constitute collectively the column structure; and; a column top support structure located in the vicinity of the upper part of a column structure so assembled; characterized in that each column module is mechanically supported from the column top support structure; and in that each column module comprises a plurality of vertically disposed sub-modules arrayed successively above one another to constitute the column module, each sub-module comprising a basket for the containment of a discrete portion of high surface area packing material having at least a horizontal support surface adapted to carry the discrete portion of high surface area packing material.
A method, comprising: detecting the presence of a FIG- ROS fusion polypeptide in a biological sample of a human lung cancer or suspected lung cancer, wherein the lung cancer is non-small cell lung carcinoma (NSCLC).
Process of printing high resolution, preferably medical, devices with complex geometries, comprising the steps of: - printing a model with a three-dimensional printing method by using a three-dimensional printer; said model positive reproducing the medical device to be made; - said model being printed of a first water-soluble polymer or aqueous solutions; - covering said model with a layer of material insoluble to a solution able to dissolve said first soluble polymer; said covering step making a shell of solid mold provided with a surface comprising empty interstitial spots; - infiltrating an amount of water or aqueous solution into said solid mold through said empty interstitial spots so that to dissolve said model and to make a mold cavity negative reproducing said model; - infiltrating into the mold cavity, through the outer walls of said mold, a second liquid polymer; said material having a melting temperature greater than the melting temperature of said second liquid polymer and/or a difference in the Hildebrand solubility parameter greater than or equal to 2 cal 1/2 cm -3/2 with respect to that of said second liquid polymer; said step of infiltrating into the mold cavity occurs by depositing the liquid polymer on the outer walls of said mold, wherein the second liquid polymer solidifies or hardens in the mold cavity and the device is formed; - removing said mold by releasing the product obtained and created in said second polymer. - printing a model with a three-dimensional printing method by using a three-dimensional printer; said model positive reproducing the medical device to be made; - said model being printed of a first water-soluble polymer or aqueous solutions; - covering said model with a layer of material insoluble to a solution able to dissolve said first soluble polymer; said covering step making a shell of solid mold provided with a surface comprising empty interstitial spots; - infiltrating an amount of water or aqueous solution into said solid mold through said empty interstitial spots so that to dissolve said model and to make a mold cavity negative reproducing said model; - infiltrating into the mold cavity, through the outer walls of said mold, a second liquid polymer; said material having a melting temperature greater than the melting temperature of said second liquid polymer and/or a difference in the Hildebrand solubility parameter greater than or equal to 2 cal 1/2 cm -3/2 with respect to that of said second liquid polymer; said step of infiltrating into the mold cavity occurs by depositing the liquid polymer on the outer walls of said mold, wherein the second liquid polymer solidifies or hardens in the mold cavity and the device is formed; - removing said mold by releasing the product obtained and created in said second polymer.
Method for producing a lamp having a substrate on which at least one semiconductor chip for emitting light radiation is arranged, a cover covering the at least one semiconductor chip being sealingly associated with the substrate and a bridge connecting the legs extending at a distance from the substrate so that an air space is present between the substrate and the interior of the cover, in which air space the semiconductor chips are arranged at a distance from the cover, and the cover being completely encased on its outer side by a plastics mass permeable to light radiation, characterized in that legs of the cover bear against the substrate in a clamping manner.
A method for producing a polyester comprising adding a phosphorus compound represented by the following formula to a reaction system, in a method for obtaining a polyester comprising esterification or transesterification-reacting dicarboxylic acid or an ester-forming derivative thereof, and a diol or an ester-forming derivative thereof, and polycondensing this in the presence of a titanium-based polycondensation catalyst. (in the formula, X represents a hydrocarbon group of a carbon number of 1 to 10, or sulfur, the hydrocarbon group may contain one or more of an alicyclic structure, an aromatic ring structure and a double bond, or may contain a substituent, R 5 to R 8 each represent independently a group selected from a hydroxy group, a hydrocarbon group of a carbon number of 1 to 30, and an alkoxy group of a carbon number of 1 to 30, the hydrocarbon group may contain one or more structures selected from an alicyclic structure, an aliphatic branched structure, an aromatic ring structure and a double bond, R 9 to R 12 each represent independently a group selected from a hydroxy group, a hydrocarbon group of a carbon number of 1 to 10, and an alkoxy group of a carbon number of 1 to 10, the hydrocarbon group may contain one or more structures selected from an alicyclic structure, an aliphatic branched group, an aromatic ring structure and a double bond, and a+b, and c+d are each an integer of 0 to 4)