An apparatus (100, 200, 300, 400) for infusing liquid and sealing an indwelling medical device comprising: a syringe body (112, 212, 312, 412) having an outer wall (115, 215, 315, 415) defining a lumen extending therethrough and further including a proximal end and a distal end, and wherein the outer wall (115, 215, 315, 415) defines an opening at the distal end of the syringe body (112, 212, 312, 412); a plunger (114, 214, 314, 414) having a proximal end (116, 216, 316, 416) and a distal end (118, 218, 318, 418) slidably disposed within the lumen of the syringe body (112, 212, 312, 412), such that the plunger (114, 214, 314, 414) slides from the proximal end of the syringe body (112, 212, 312, 412) to the distal end of the syringe body (112, 212, 312, 412); a plunger seal (124, 224, 324, 424) disposed at the distal end (118, 218, 318, 418) of the plunger (114, 214, 314, 414), and being separable from the distal end (118, 218, 318, 418) of the plunger (114, 214, 314, 414), a cap (128, 228, 328, 428) defining an opening through which infusing liquid can travel, the cap (128, 228, 328, 428) being disposed at the distal end of the syringe body (112, 212, 312, 412) within the opening of the lumen defined by the outer wall (115, 215, 315, 415) of the syringe body (112, 212, 312, 412), the cap (128, 228, 328, 428) being configured to couple to an end of the indwelling medical device, the apparatus characterized by: a first notch (131, 231, 331, 431) defined by the outer wall (115, 215, 315, 415) of the syringe body (112, 212, 312, 412) and positioned proximate of the opening at the distal end of the syringe body (112, 212, 312, 412); and a pinch release ring (130, 230, 330, 430, 530) having a finger (133, 233, 333, 433, 533) which couples with the first notch (131, 231, 331, 431),wherein the cap (128, 228, 328, 428) is configured to be separated from the syringe body and defines a second notch (131a, 231a, 331a, 431a) with which the finger (133, 233, 333, 433, 533) of the pinch release ring (130, 230, 330, 430, 530) can couple, and the plunger seal (124, 224, 324, 424) being coupleable to the cap (128, 228, 328, 428) to seal the cap (128, 228, 328, 428). a syringe body (112, 212, 312, 412) having an outer wall (115, 215, 315, 415) defining a lumen extending therethrough and further including a proximal end and a distal end, and wherein the outer wall (115, 215, 315, 415) defines an opening at the distal end of the syringe body (112, 212, 312, 412); a plunger (114, 214, 314, 414) having a proximal end (116, 216, 316, 416) and a distal end (118, 218, 318, 418) slidably disposed within the lumen of the syringe body (112, 212, 312, 412), such that the plunger (114, 214, 314, 414) slides from the proximal end of the syringe body (112, 212, 312, 412) to the distal end of the syringe body (112, 212, 312, 412); a plunger seal (124, 224, 324, 424) disposed at the distal end (118, 218, 318, 418) of the plunger (114, 214, 314, 414), and being separable from the distal end (118, 218, 318, 418) of the plunger (114, 214, 314, 414), a cap (128, 228, 328, 428) defining an opening through which infusing liquid can travel, the cap (128, 228, 328, 428) being disposed at the distal end of the syringe body (112, 212, 312, 412) within the opening of the lumen defined by the outer wall (115, 215, 315, 415) of the syringe body (112, 212, 312, 412), the cap (128, 228, 328, 428) being configured to couple to an end of the indwelling medical device, the apparatus characterized by: a first notch (131, 231, 331, 431) defined by the outer wall (115, 215, 315, 415) of the syringe body (112, 212, 312, 412) and positioned proximate of the opening at the distal end of the syringe body (112, 212, 312, 412); and a pinch release ring (130, 230, 330, 430, 530) having a finger (133, 233, 333, 433, 533) which couples with the first notch (131, 231, 331, 431),wherein the cap (128, 228, 328, 428) is configured to be separated from the syringe body and defines a second notch (131a, 231a, 331a, 431a) with which the finger (133, 233, 333, 433, 533) of the pinch release ring (130, 230, 330, 430, 530) can couple, and the plunger seal (124, 224, 324, 424) being coupleable to the cap (128, 228, 328, 428) to seal the cap (128, 228, 328, 428). a first notch (131, 231, 331, 431) defined by the outer wall (115, 215, 315, 415) of the syringe body (112, 212, 312, 412) and positioned proximate of the opening at the distal end of the syringe body (112, 212, 312, 412); and a pinch release ring (130, 230, 330, 430, 530) having a finger (133, 233, 333, 433, 533) which couples with the first notch (131, 231, 331, 431),wherein the cap (128, 228, 328, 428) is configured to be separated from the syringe body and defines a second notch (131a, 231a, 331a, 431a) with which the finger (133, 233, 333, 433, 533) of the pinch release ring (130, 230, 330, 430, 530) can couple, and the plunger seal (124, 224, 324, 424) being coupleable to the cap (128, 228, 328, 428) to seal the cap (128, 228, 328, 428).