mhurhangee/ep-ind-claims huggingface dataset:
Method for obtaining a door or window frame forming a right angle between at least two profiled members, each of said profiled members being delimited by an inner edge, an outer edge and at least one facing, said method comprising the following steps: - a cutting step during which each of said profiled members are cut aslant along a slanted cutting plane normal to said facing, - a forging step during which said profiled members are assembled together in order to form a right angle, putting said slanted cutting planes in contact, said method being characterised in that, during said cutting step, said profiled members are cut aslant at a slanted cutting angle (α) between said outer edge and said slanted cutting plane that is strictly greater than 45°, and in that, during said forging step, said slanted cutting planes are deformed at least locally so as to form a welding bead the size of which decreases from said inner edge towards said outer edge. - a cutting step during which each of said profiled members are cut aslant along a slanted cutting plane normal to said facing, - a forging step during which said profiled members are assembled together in order to form a right angle, putting said slanted cutting planes in contact,
A compound of general formula wherein R 1 is (C 1 -C 4)alkyl; and R 2 is selected from the group consisting of (C 1 -C 4)alkyl, (C 3 -C 6)cycloalkyl or bridged (C 3 -C 6)cycloalkyl, (4-8 membered) heterocycloalkyl or bridged (4-8 membered) heterocycloalkyl, and phenyl; all of which are optionally substituted with one or more substituents independently selected from R 3; and R 3 is selected from the group consisting of halogen, -CN, -OH, (C 1 -C 4)alkyl, halo(C 1 -C 4)alkyl, hydroxy(C 1 -C 4)alkyl, (C 1 -C 6)alkoxy, and halo(C 1 -C 4)alkyloxy; and S* represents a chiral sulfur atom with stereochemistry; or pharmaceutically acceptable salts, enantiomers, mixtures of enantiomers, diastereomers, mixtures of diastereomers, hydrates and solvates thereof. R 1 is (C 1 -C 4)alkyl; and R 2 is selected from the group consisting of (C 1 -C 4)alkyl, (C 3 -C 6)cycloalkyl or bridged (C 3 -C 6)cycloalkyl, (4-8 membered) heterocycloalkyl or bridged (4-8 membered) heterocycloalkyl, and phenyl; all of which are optionally substituted with one or more substituents independently selected from R 3; and R 3 is selected from the group consisting of halogen, -CN, -OH, (C 1 -C 4)alkyl, halo(C 1 -C 4)alkyl, hydroxy(C 1 -C 4)alkyl, (C 1 -C 6)alkoxy, and halo(C 1 -C 4)alkyloxy; and S* represents a chiral sulfur atom with stereochemistry; or pharmaceutically acceptable salts, enantiomers, mixtures of enantiomers, diastereomers, mixtures of diastereomers, hydrates and solvates thereof.
A method for selecting a membrane protein with increased stability, the method comprising: a) providing one or more mutants of a parent membrane protein in a membrane-containing composition, wherein the one or more mutants are exposed to an amount of a membrane destabilising agent which is effective to destabilise the parent membrane protein in-situ, and wherein following exposure to said amount of membrane destabilising agent, the one or more mutants are destabilised in-situ, b) determining whether the or each mutant membrane protein, when destabilised in-situ, has increased stability with respect to its structure and/or a biological activity compared to the stability of the parent membrane protein, when destabilised in-situ, with respect to its structure and/or the same biological activity, and c) selecting the one or more mutants which have increased stability compared to the stability of the parent membrane protein. a) providing one or more mutants of a parent membrane protein in a membrane-containing composition, wherein the one or more mutants are exposed to an amount of a membrane destabilising agent which is effective to destabilise the parent membrane protein in-situ, and wherein following exposure to said amount of membrane destabilising agent, the one or more mutants are destabilised in-situ, b) determining whether the or each mutant membrane protein, when destabilised in-situ, has increased stability with respect to its structure and/or a biological activity compared to the stability of the parent membrane protein, when destabilised in-situ, with respect to its structure and/or the same biological activity, and c) selecting the one or more mutants which have increased stability compared to the stability of the parent membrane protein.
A recombinant or synthetic protein including: - a first region having a sequence encoded by a gene that encodes a component of a Mycobacterium sulphate assimilation pathway, wherein the gene is a Mycobacterium CysD gene that has at least 75% identity with SEQ ID NO: 1; and - a further region having a sequence encoded by a Mycobacterium Ag85B gene that has a sequence as shown in SEQ ID NO: 5. - a first region having a sequence encoded by a gene that encodes a component of a Mycobacterium sulphate assimilation pathway, wherein the gene is a Mycobacterium CysD gene that has at least 75% identity with SEQ ID NO: 1; and - a further region having a sequence encoded by a Mycobacterium Ag85B gene that has a sequence as shown in SEQ ID NO: 5.
A method for selecting hybridoma cells from a plurality of cells, the hybridoma cell comprising a surface protein having an extracellularly exposed ligation peptide sequence for enzymatic conjugation of an adapter ligand that is suitable for the direct or indirect coupling of a molecular catcher structure comprising at least one specific binding site for the released antibodies at a distance from the specific binding site, comprising an enzymatic conjugation of the adapter ligand biotin with the ligation peptide sequence GLNDIFEAQKIEWHE, the direct or indirect coupling of the molecular catcher structure at a distance from the specific binding site, and the specific binding of at least one of the released antibodies to the specific binding site, wherein the molecular catcher structure is an antigen, the specific binding site is an epitope, and the released antibodies are antibodies or antibody constitutes directed against the epitope, and the antibody is detectable.
A medium- or large-sized battery pack having a plurality of unit cells, wherein the battery pack is constructed in a structure characterised in that: the battery pack further comprises a sealed container; perfluoroketone, as a fire extinguishing agent, is disposed in the container in a sealed state; and the container is arranged so that the sealed container will be broken due to an increase of vapor pressure caused by the evaporation of the perfluoroketone when the temperature of the battery pack is increased, whereby the evaporated perfluoroketone will be ejected. the battery pack further comprises a sealed container; perfluoroketone, as a fire extinguishing agent, is disposed in the container in a sealed state; and the container is arranged so that the sealed container will be broken due to an increase of vapor pressure caused by the evaporation of the perfluoroketone when the temperature of the battery pack is increased, whereby the evaporated perfluoroketone will be ejected.
Method for determining the nitrogen oxide content and/or ammonia content in the exhaust gas of an internal combustion engine which comprises a catalytic converter, preferably three-way catalytic converter, arranged in an exhaust tract of the internal combustion engine and an exhaust gas sensor arranged downstream of the catalytic converter, wherein the method comprises: - generating a linear and/or binary lambda signal which indicates the lambda value by means of the exhaust gas sensor, - determining a lambda value based on the generated linear and/or binary lambda signal, - determining an operating state of the internal combustion engine which indicates a lean operation or a rich operation of the internal combustion engine based at least partially on the determined lambda value, - generating at least one signal by means of the exhaust gas sensor that indicates the proportion of nitrogen oxide and/or ammonia in the exhaust gas, and - determining the nitrogen oxide content and/or ammonia content in the exhaust gas of the internal combustion engine at least partially based on the determined operating state of the internal combustion engine and at least partially based on the at least one signal of the exhaust gas sensor. - generating a linear and/or binary lambda signal which indicates the lambda value by means of the exhaust gas sensor, - determining a lambda value based on the generated linear and/or binary lambda signal, - determining an operating state of the internal combustion engine which indicates a lean operation or a rich operation of the internal combustion engine based at least partially on the determined lambda value, - generating at least one signal by means of the exhaust gas sensor that indicates the proportion of nitrogen oxide and/or ammonia in the exhaust gas, and - determining the nitrogen oxide content and/or ammonia content in the exhaust gas of the internal combustion engine at least partially based on the determined operating state of the internal combustion engine and at least partially based on the at least one signal of the exhaust gas sensor.
Device for reducing pathogenic microbes, which device is in the form of a hand-held device, comprising a hand grip, a negative terminal coming into contact with the body, and also a device head with a positive terminal, wherein a low electrical voltage can be generated in the hand-held device between the terminals, characterized in that the positive terminal on the device head is in the form of a round or elliptical or rod-shaped body composed of silver which is configured to release positive ions into the body tissue upon closing the electric circuit, and the negative terminal in the hand grip of the hand-held device is integrated as a conductive zone in the midsection of said hand grip.
Windscreen wiper drive for driving at least a first windscreen wiper of a motor vehicle, said windscreen wiper drive comprising an electric motor which is provided for driving a drive shaft which extends in the direction of a drive axis and, in an operating state, is rotatable about the drive axis • in a direction of rotation to an upper turning point and • counter to the direction of rotation into a lower turning point, wherein the windscreen wiper drive comprises a mechanical retaining means (16, 17) which is provided in order to releasably retain the drive shaft in a loaded inoperative state in a holding position, which is arranged below the lower turning point counter to the direction of rotation, against inadvertent rotation in the direction of rotation, characterized in that the retaining means (16, 17) is a snap-action means which is released when a retaining load which is greater than a wind load is exceeded. • in a direction of rotation to an upper turning point and • counter to the direction of rotation into a lower turning point,
A method comprising: receiving, with a management device, an initial transmission control protocol synchronize packet output by a managed device as a TCP client as a request to initiate a TCP session between the management device and the managed device; outputting a TCP synchronize-acknowledged (SYN-ACK) packet from the management device to accept the TCP session as a TCP server; after establishing the TCP session, receiving with the management device a role reversal message output by the managed device specifying an identity of the managed device; comparing the identity of the managed device specified in the role reversal message to a device ID stored on a database; and based on the comparing, initiating, with the management device, a secure shell connection over the TCP session in accordance with a secure shell protocol such that the management device acts as a client for the SSH protocol and the managed device acts as the server for the SSH protocol. receiving, with a management device, an initial transmission control protocol synchronize packet output by a managed device as a TCP client as a request to initiate a TCP session between the management device and the managed device; outputting a TCP synchronize-acknowledged (SYN-ACK) packet from the management device to accept the TCP session as a TCP server; after establishing the TCP session, receiving with the management device a role reversal message output by the managed device specifying an identity of the managed device; comparing the identity of the managed device specified in the role reversal message to a device ID stored on a database; and based on the comparing, initiating, with the management device, a secure shell connection over the TCP session in accordance with a secure shell protocol such that the management device acts as a client for the SSH protocol and the managed device acts as the server for the SSH protocol.
Multiple plasma burner unit for making a contour cut or bevel cut, comprising a burner holder with a middle plasma burner, a leading plasma burner and a trailing plasma burner, said plasma burners (30, 32, 34) being connected to hose assemblies (36, 38, 40) respectively and operable simultaneously, and said plasma burners (30, 32, 34) being connected to the burner holder such that their longitudinal axes (46, 52, 58) are settable at angles α, β, γ respectively to a workpiece surface of a workpiece, said burner holder being rotatably arranged on a height-adjustable arm eccentrically about a rotary axis, wherein the rotatable arrangement is achieved by means of a hollow shaft, said leading plasma burner and said trailing plasma burner are movably arranged on motor-driven carriages (48, 54) respectively on arc-shaped angle setting devices (50, 56) respectively for program-controlled setting of said angles β, γ by means of a control unit during the cutting operation, and said individual hose assemblies (36, 38, 40) are twistably held by said hollow shaft running along said rotary axis inside said arm.
Planar heating module, in particular for a planar heating system, said planar heating module having an electrically-insulating base body, having at least one electrode (12, 13) that can be electrically contacted and is arranged on the base body, said electrode extending in a continuous manner in a strip-shape along the base body, and said planar heating module having a heating layer that can be operated electrically, said layer being in physical contact in sections with the respective electrode (12, 13), wherein the electrode (12, 13) comprises at least one longitudinal section that forms a thermal expansion compensating region, characterised in that the thermal expansion compensating region comprises at least two lateral cut-outs (21, 22, 26) that are spaced apart from one another and are provided starting on opposite-lying longitudinal side edges (20, 24) of the electrode (12, 13), and that the respective cut-out (21, 22, 26) extends along a centre longitudinal line of the electrode (12, 13).
A wire which is formed of a magnetocaloric material having a magnetocaloric effect, wherein an outer surface of the wire partially has at least one of a concave portion and a convex portion in a longitudinal direction of the wire, the concave portion is recessed in a radial direction of the wire, and the convex portion protrudes in the radial direction.
Process for distillative separation of a mixture of three or more components comprising at least one low boiler, at least one middle boiler and at least one high boiler, wherein the mixture of three or more components is supplied to a first distillation column, wherein three distillation columns (K1, k2, K3) are present which are coupled with one another so as to allow mass transfer such that vapors from a first distillation column are communicatively connected to the rectifying section of a second distillation column and the rectifying section of the second distillation column is communicatively connected to the vapors of a third distillation column and bottom draws from the first distillation column are communicatively connected to the stripping section of the second distillation column and the stripping section of the second distillation column is communicatively connected to the bottom of the third distillation column, wherein the second distillation column comprises a horizontal impermeable dividing wall dividing the stripping section and rectifying section of the second distillation column, wherein the second distillation column comprises an evaporator and also a condenser, wherein a bottoms fraction comprising at least one high boiler and a tops fraction comprising at least one low boiler are removed from the second distillation column, wherein at least one middle boiler is removed from a side draw of the third distillation column.
An injection device for self-administration of settable doses of a liquid drug comprising: a housing grippable by a user, a dose setting element by which the size of the dose is set, a needle cannula having a distal tip for penetrating the skin of the user during injection, a needle shield which is telescopically movable in a proximal direction from a first position to a second position and in a distal direction from the second position back to the first position by a resilient element, and wherein the needle shield in the first position is extended distally to cover at least the distal tip of the needle cannula and in the second position is retracted proximally to expose the distal tip of the needle cannula, and a rotatable scale sleeve indicating the size of the set dose which scale sleeve is helically guided relatively to the housing, the scale sleeve being helically moved away from an initial "zero" position during dose setting and helically returned to the same initial "zero" position during dose injection, characterized in that a stopping means interconnects the needle shield and the scale sleeve, which stopping means engages the scale sleeve when the scale sleeve is in the "zero" position such that the needle shield is prevented from being moved in the proximal direction from the first position and into the second position but is allowed to be moved in the distal direction from the second position and into the first position, and, the needle shield carries the stopping means such that the needle shield and the stopping means move together at least in the axially direction. a housing grippable by a user, a dose setting element by which the size of the dose is set, a needle cannula having a distal tip for penetrating the skin of the user during injection, a needle shield which is telescopically movable in a proximal direction from a first position to a second position and in a distal direction from the second position back to the first position by a resilient element, and wherein the needle shield in the first position is extended distally to cover at least the distal tip of the needle cannula and in the second position is retracted proximally to expose the distal tip of the needle cannula, and a rotatable scale sleeve indicating the size of the set dose which scale sleeve is helically guided relatively to the housing, the scale sleeve being helically moved away from an initial "zero" position during dose setting and helically returned to the same initial "zero" position during dose injection, characterized in that a stopping means interconnects the needle shield and the scale sleeve, which stopping means engages the scale sleeve when the scale sleeve is in the "zero" position such that the needle shield is prevented from being moved in the proximal direction from the first position and into the second position but is allowed to be moved in the distal direction from the second position and into the first position, and, the needle shield carries the stopping means such that the needle shield and the stopping means move together at least in the axially direction.
A suspension system comprising first and second support elements, configured to be vertically arranged, first and second brackets, each configured to be attached to a respective one of the support elements in a cantilevered fashion, wherein each bracket has a U-shaped cross-section with first and second leg portions and an interconnecting lower bend portion, and a frame (7, 27), comprising side portions each configured to be attached to a respective one of the brackets by means of a fastening arrangement at each bracket, a guided part of the frame being slideable in and out of an area in between the brackets and comprising a holding device, the fastening arrangement comprising the combination of: - a mid-section attachment device (19, 23, 25) including a centre cut-out in the mid third of the bracket and in a leg portion thereof, an attachment tongue on the side portion, which is configured to be inserted into the centre cut-out to clasp the edge thereof, and a bulb adapted to snap into the centre cut-out, and - a front attachment device including a front cut-out in the cantilevered end of the bracket, in said leg portion thereof, a front attachment tongue on the side portion, which is configured to be inserted into the front cut-out to clasp the edge thereof, the suspension system being characterized in that the front attachment device includes a support tongue configured to abut the lower portion of the bracket, such that a nose portion of the bracket is wedged in between the front attachment tongue and the support tongue. - a mid-section attachment device (19, 23, 25) including a centre cut-out in the mid third of the bracket and in a leg portion thereof, an attachment tongue on the side portion, which is configured to be inserted into the centre cut-out to clasp the edge thereof, and a bulb adapted to snap into the centre cut-out, and - a front attachment device including a front cut-out in the cantilevered end of the bracket, in said leg portion thereof, a front attachment tongue on the side portion, which is configured to be inserted into the front cut-out to clasp the edge thereof,
Locking system (1, 2) for locking two locking partners (1, 2), the first locking partner having a bolt which is movable in a translational direction of movement between an unlocking position and a locking position, characterized in that the bolt has a first magnet, the first locking partner also having a second magnet, the direction of magnetization of the first magnet corresponding to the translational direction of movement of the bolt, and the direction of magnetization of the second magnet being oriented perpendicularly to the direction of magnetization of the first magnet. the first locking partner having a bolt which is movable in a translational direction of movement between an unlocking position and a locking position, characterized in that the bolt has a first magnet, the first locking partner also having a second magnet, the direction of magnetization of the first magnet corresponding to the translational direction of movement of the bolt, and the direction of magnetization of the second magnet being oriented perpendicularly to the direction of magnetization of the first magnet.
A method for controlling a process section for refining of fibrous material, said process section comprising at least one first refiner driven by at least one motor, and having a control unit, said method comprising measuring, alternatively estimating, one or more process variables representing external states outside of the refiner (η 1 Q 1) for said process section, and the possibility to manipulate at least two variables ( u 1) using a multivariable control method, and calculating changes for said at least two manipulated variable ( u 1) for said at least one refiner using said measurement, alternatively estimate, of an external state (η 1, Q 1) and wherein a setpoint (ω m) for any motor speed within a predetermined range of motor speeds for a variable motor speed of at least one refiner motor is one of said manipulated variables ( u 1), and wherein a setpoint (P inlet) for inlet pressure is one of said manipulated variables ( u 1).