mhurhangee/ep-ind-claims huggingface dataset:
A method of monitoring the immune status of a subject, comprising: (a) detecting an amount of BCMA polypeptide in a biological sample that has been obtained from the subject; and (b) comparing the amount of BCMA polypeptide detected in (a) to a predetermined cut-off value or to an amount detected in a control serum sample, wherein a decreased amount of BCMA polypeptide in the biological sample of the subject as compared to the predetermined cut-off value or amount in the control serum or plasma sample is indicative of an impaired immune system as the result of an immunodeficiency disease selected from the group consisting of: X-linked agammaglobulinemia, Common Variable Immune Deficiency (CVID), IgG Deficiency, IgM Deficiency, or Hyper IgM Syndrome, wherein the biological sample is a serum or plasma sample or supernatant obtained from a culture of the subject's bone marrow mononuclear cells or peripheral blood mononuclear cells and wherein the BCMA polypeptide comprises the amino acid sequence of SEQ ID NO:1 or an amino acid sequence having at least about 75, 80 or 90% identity with SEQ ID NO:1. (a) detecting an amount of BCMA polypeptide in a biological sample that has been obtained from the subject; and (b) comparing the amount of BCMA polypeptide detected in (a) to a predetermined cut-off value or to an amount detected in a control serum sample, wherein a decreased amount of BCMA polypeptide in the biological sample of the subject as compared to the predetermined cut-off value or amount in the control serum or plasma sample is indicative of an impaired immune system as the result of an immunodeficiency disease selected from the group consisting of: X-linked agammaglobulinemia, Common Variable Immune Deficiency (CVID), IgG Deficiency, IgM Deficiency, or Hyper IgM Syndrome, wherein the biological sample is a serum or plasma sample or supernatant obtained from a culture of the subject's bone marrow mononuclear cells or peripheral blood mononuclear cells and wherein the BCMA polypeptide comprises the amino acid sequence of SEQ ID NO:1 or an amino acid sequence having at least about 75, 80 or 90% identity with SEQ ID NO:1.
A projection optical system, comprising: a light source array; a projection gate; a projection lens configured to project an image of the projection gate, wherein the projection gate is located between the light source array and the projection lens; and a relay lens group located between the light source array and the projection gate; a field stop, wherein the light source array is located in a volume contiguous to the field stop; and wherein the relay lens group is configured to prevent the projection lens from projecting an image of the light source array. a light source array; a projection gate; a projection lens configured to project an image of the projection gate, wherein the projection gate is located between the light source array and the projection lens; and a relay lens group located between the light source array and the projection gate; a field stop, wherein the light source array is located in a volume contiguous to the field stop; and wherein the relay lens group is configured to prevent the projection lens from projecting an image of the light source array.
A pharmaceutical composition for use in promoting muscle regeneration, which comprises an IL-6 inhibitor as an active ingredient wherein the IL-6 inhibitor is an antibody that recognizes an IL-6 receptor.
A compound represented by the following general formula (1 A): wherein the solid lines represent a single bonds and the double lines represent double bonds, C represents a carbon atom, H represents a hydrogen atom and N represents a nitrogen atom, each of R 4, R 5, R 6, R 7, R 8, R 9, R 10, R 11, R 12, R 13, R 14, and R 15 independently represents a group selected from the group consisting of a hydrogen atom, an alkyl group, a cycloalkyl group, an aryl group, and an aralkyl group, and G represents a group selected from the group consisting of a monovalent group represented by the following general formula (G P) and a monovalent group represented by the following general formula (G S): wherein the solid lines represent a single bonds, a dotted line represents a coordinate bond and a solid line intersected by a wavy line represents a bond to an adjacent atom, P represents a phosphorus atom, L represents a lone electron pair or a boron trihydride, each of R 1 and R 2 independently represents a group selected from the group consisting of an alkyl group, a cycloalkyl group, an alkenyl group that may have a substituent, an aryl group that may have a substituent, a heteroaryl group that may have a substituent, and an aralkyl group that may have a substituent, and R 1 and R 2 may combine with each other to form a phosphorus atom-containing ring that may have a substituent; and wherein a solid line represents a single bond and a solid line intersected by a wavy line represents a bond to an adjacent atom, S represents a sulfur atom, and R 3 represents a group selected from the group consisting of an alkyl group, a cycloalkyl group, an alkenyl group that may have a substituent, an aryl group that may have a substituent, a heteroaryl group that may have a substituent, and an aralkyl group that may have a substituent.
A method of printing a yarn onto a base, the method comprising: dispensing the yarn from a nozzle of a printing system, the yarn including a heat-moldable material and a melt-resistant material; wherein the step of dispensing the yarn comprises dispensing the heat-moldable material in a liquid state and wherein the step of dispensing the yarn comprises dispensing the melt-resistant material in a solid state; selectively attaching the yarn to an attachment region (152, 210) of the base by moving the nozzle along a first axis into the attachment region (152, 210); wherein the first axis is approximately normal to an upper surface; wherein the base has the upper surface spaced from a lower surface by a base thickness; wherein the step of moving the nozzle along the first axis into the attachment region (152, 210) reduces the base thickness by a prodding distance; and wherein the heat-moldable material bonds to the attachment region (152, 210) during a transition of the heat-moldable material from the liquid state to a solid state of the heat-moldable material. dispensing the yarn from a nozzle of a printing system, the yarn including a heat-moldable material and a melt-resistant material; wherein the step of dispensing the yarn comprises dispensing the heat-moldable material in a liquid state and wherein the step of dispensing the yarn comprises dispensing the melt-resistant material in a solid state; selectively attaching the yarn to an attachment region (152, 210) of the base by moving the nozzle along a first axis into the attachment region (152, 210); wherein the first axis is approximately normal to an upper surface; wherein the base has the upper surface spaced from a lower surface by a base thickness; wherein the step of moving the nozzle along the first axis into the attachment region (152, 210) reduces the base thickness by a prodding distance; and wherein the heat-moldable material bonds to the attachment region (152, 210) during a transition of the heat-moldable material from the liquid state to a solid state of the heat-moldable material.
A surgical implant for correcting the mutual positioning or orientation of the bones of a patient designed to be inserted between at least two bone bodies (2, 3) of said patient, said surgical implant comprising: - a main body extending along a longitudinal axis (X-X') between a proximal end and a distal end of said main body, - a plurality of fins, each fin being provided with a junction edge connecting said fin to said main body, such that said fins protrude from said main body from the respective junction edge thereof, which substantially extends in a junction plane (Pj) whose normal is formed by said longitudinal axis (X-X'), each fin comprises a free edge and extends between the junction edge and the free edge, the surgical implant being characterized in that each fin has a sufficient flexibility so that it can be deformed along a direction centripetal and/or parallel to the longitudinal axis (X-X') under the action of at least one of the bone bodies (2, 3) when said surgical implant is inserted between said bone bodies (2, 3) and in that each fin has at least: - one portion of constant width along which the free edge and the junction edge are separated by a first distance substantially constant along said portion of constant width and, - one flat portion, along which the free edge and the junction edge are separated by a second distance lower than the first distance. - a main body extending along a longitudinal axis (X-X') between a proximal end and a distal end of said main body, - a plurality of fins, each fin being provided with a junction edge connecting said fin to said main body, such that said fins protrude from said main body from the respective junction edge thereof, which substantially extends in a junction plane (Pj) whose normal is formed by said longitudinal axis (X-X'), each fin comprises a free edge and extends between the junction edge and the free edge, - one portion of constant width along which the free edge and the junction edge are separated by a first distance substantially constant along said portion of constant width and, - one flat portion, along which the free edge and the junction edge are separated by a second distance lower than the first distance.
A method for constructing a concrete overhang on the wall of a building, said method comprising casting a concrete slab and placing the slab to be supported upon wall-mounted cantilever beams, wherein: - an enclosure in alignment with each beam is provided in the concrete slab, within said enclosures the beams settle as the slab is placed to be supported upon the beams, and - the slab is placed upon the beams for support, and - the slab is secured to the beams, characterized in that - the enclosures are fixed to the bottom surface of the concrete slab, - the slab has openings, which are in alignment with the beams and which include a plate provided with a threaded hole, and - the distance of the slab from the beam is adjusted before the slab is secured such that the slab settles exactly at a desired height and that the distance of the slab from the beam, when the slab is placed upon the beams for support, is adjusted by means of bolts to be screwed into the holes. - an enclosure in alignment with each beam is provided in the concrete slab, within said enclosures the beams settle as the slab is placed to be supported upon the beams, and - the slab is placed upon the beams for support, and - the slab is secured to the beams, characterized in that - the enclosures are fixed to the bottom surface of the concrete slab, - the slab has openings, which are in alignment with the beams and which include a plate provided with a threaded hole, and - the distance of the slab from the beam is adjusted before the slab is secured such that the slab settles exactly at a desired height and that the distance of the slab from the beam, when the slab is placed upon the beams for support, is adjusted by means of bolts to be screwed into the holes.
A power supply for providing power to a lithography illumination source, the power supply comprising: a voltage source (310, 400) configured to provide the power; and a transmission line (T 1) configured to transmit the power from the voltage source (310, 400); characterised by a RF termination (360, 380) provided on an input end of the transmission line (T 1) or an output end of the transmission line (T 1), the RF termination (360, 380) being configured to terminate the transmission line (T 1) to reduce reflection of RF energy at the end of the transmission line (T 1). a voltage source (310, 400) configured to provide the power; and a transmission line (T 1) configured to transmit the power from the voltage source (310, 400); characterised by a RF termination (360, 380) provided on an input end of the transmission line (T 1) or an output end of the transmission line (T 1), the RF termination (360, 380) being configured to terminate the transmission line (T 1) to reduce reflection of RF energy at the end of the transmission line (T 1).
A pneumatic tire comprising: a pair of bead cores; a carcass ply comprising a main body positioned between the bead cores and a turn-up portion connected to the main body and formed by turning up around each bead core from inside to outside in a tire width direction; a cover rubber covering the main body of the carcass ply and an outer side of the turn-up portion in the tire width direction and configuring a tire outer surface; and a reinforcement layer (21, 121) located inward from the tire outer surface of the cover rubber and covering an outer side, in the tire width direction, of at least a portion of the turn-up portion of the carcass ply, wherein the reinforcement layer is configured by a non-woven fabric formed from metal fibers; wherein in a tire widthwise cross-sectional view, at least a portion of the reinforcement layer is located in a region, in a tire radial direction, that is from 5% to 30% of a tire section height from an inner edge of the bead core in the tire radial direction outward in the tire radial direction; wherein in the tire widthwise cross-sectional view, the reinforcement layer extends from a position farther outward, in the tire radial direction, than an outer edge of the bead core in the tire radial direction to a position farther inward; and wherein in the tire widthwise cross-sectional view, the reinforcement layer is turned up around the bead core from an outer side towards an inner side in the tire width direction. a pair of bead cores; a carcass ply comprising a main body positioned between the bead cores and a turn-up portion connected to the main body and formed by turning up around each bead core from inside to outside in a tire width direction; a cover rubber covering the main body of the carcass ply and an outer side of the turn-up portion in the tire width direction and configuring a tire outer surface; and a reinforcement layer (21, 121) located inward from the tire outer surface of the cover rubber and covering an outer side, in the tire width direction, of at least a portion of the turn-up portion of the carcass ply, wherein the reinforcement layer is configured by a non-woven fabric formed from metal fibers; wherein in a tire widthwise cross-sectional view, at least a portion of the reinforcement layer is located in a region, in a tire radial direction, that is from 5% to 30% of a tire section height from an inner edge of the bead core in the tire radial direction outward in the tire radial direction; wherein in the tire widthwise cross-sectional view, the reinforcement layer extends from a position farther outward, in the tire radial direction, than an outer edge of the bead core in the tire radial direction to a position farther inward; and wherein in the tire widthwise cross-sectional view, the reinforcement layer is turned up around the bead core from an outer side towards an inner side in the tire width direction.
An apparatus, comprising: an interposer (203; 600; 700; 800) having conductive layers (451; 452; 453; 457; 603; 604; 611; 707) disposed above a top surface of an interposer substrate, the interposer substrate having a plurality of conductors and a plurality of charge attracting structures (610; 620; 710; 720; 810; 820), the charge attracting structures (610; 620; 710; 720; 810; 820) configured to function as decoupling capacitors, the charge attracting structures (610; 620; 710; 720; 810; 820) comprising either a heavily doped n-type region (613; 813) formed in p-doped well (615; 715) or a heavily doped p-type region (614; 814) formed in n-doped well (616; 716; 816); wherein the plurality of charge attracting structures (610; 620; 710; 720; 810; 820) are configured to protect at least one integrated circuit die to be coupled to the interposer (203; 600; 700; 800) to provide a stacked die; and wherein the plurality of conductors include a plurality of through-substrate vias formed through the interposer substrate and coupled to the plurality of charge attracting structures (610; 620; 710; 720; 810; 820) through respective ones of said conductive layers (451; 452; 453; 457; 603; 604; 611; 707). an interposer (203; 600; 700; 800) having conductive layers (451; 452; 453; 457; 603; 604; 611; 707) disposed above a top surface of an interposer substrate, the interposer substrate having a plurality of conductors and a plurality of charge attracting structures (610; 620; 710; 720; 810; 820), the charge attracting structures (610; 620; 710; 720; 810; 820) configured to function as decoupling capacitors, the charge attracting structures (610; 620; 710; 720; 810; 820) comprising either a heavily doped n-type region (613; 813) formed in p-doped well (615; 715) or a heavily doped p-type region (614; 814) formed in n-doped well (616; 716; 816); wherein the plurality of charge attracting structures (610; 620; 710; 720; 810; 820) are configured to protect at least one integrated circuit die to be coupled to the interposer (203; 600; 700; 800) to provide a stacked die; and wherein the plurality of conductors include a plurality of through-substrate vias formed through the interposer substrate and coupled to the plurality of charge attracting structures (610; 620; 710; 720; 810; 820) through respective ones of said conductive layers (451; 452; 453; 457; 603; 604; 611; 707).
Control unit for controlling and/or regulating an electrical drive motor, comprising a setpoint speed sensor, comprising an actual speed detection system, comprising two switchover contacts (12, 13) fixing the direction of rotation of the drive motor and comprising a disconnection device, which is designed to switch one of the switchover contacts (12, 13) in the case of the setpoint speed being overshot by a preset amount by the actual speed for current interruption purposes, wherein the disconnection device is designed to change the switching state (12', 12", 13', 13") of the respective other switchover contact (12, 13) after the switching operation in the case of an unexpected decrease in the actual speed.
A two-component composition constituted by a component A intended to be mixed, in situ, with a component B in order to form an injectable or pumpable organo-mineral material or compound, notably for the injection-sealing of dynamic anchoring bolts, the component A comprising essentially at least one alkali metal silicate and the component B comprising essentially at least one polyisocyanate prepolymer and at least one cement, characterized in that the component A moreover contains at least one polyol with a molecular mass of between 50 and 200 g/mol, a polymerization catalyst comprising at least one primary amine or alcohol function and at least one gelling agent manifesting the final mixture of the two components A and B in the form of a gel without causing the mixture of said components to set, and in that the component B moreover comprises at least one compatible plasticizer, the final mixture of said components A and B leading to the formation of an organo-mineral material exhibiting compressive strength at 10% strain of at least 17 MPa, in accordance with the standard ISO 604, and shear strength of at least 7 MPa, in accordance with the standard AFTM D732, for setting times of between 20 seconds and 15 minutes at 20°C.
A printer comprising: a printhead configured to selectively cause a mark to be created on a substrate; a stepper motor having an output shaft coupled to the printhead, the stepper motor being arranged to vary the position of the printhead; a sensor configured to generate a signal indicative of an angular position of the output shaft of the stepper motor; and a controller arranged to generate control signals for the stepper motor; said control signals being at least partially based upon an output of said sensor and at least partially based upon a target position, wherein: said control signals for the stepper motor are arranged to cause a magnetic field to be generated by windings of the stepper motor, a field angle being defined between an angular position of the output shaft of the stepper motor, and an orientation of the generated magnetic field; said control signals comprise a first control signal configured to cause said field angle to have a predetermined value, and a second control signal configured to cause said magnetic field to have a predetermined magnitude; and said controller is configured to vary said first and second control signals based upon said target position and said output of said sensor. a printhead configured to selectively cause a mark to be created on a substrate; a stepper motor having an output shaft coupled to the printhead, the stepper motor being arranged to vary the position of the printhead; a sensor configured to generate a signal indicative of an angular position of the output shaft of the stepper motor; and a controller arranged to generate control signals for the stepper motor; said control signals being at least partially based upon an output of said sensor and at least partially based upon a target position, wherein: said control signals for the stepper motor are arranged to cause a magnetic field to be generated by windings of the stepper motor, a field angle being defined between an angular position of the output shaft of the stepper motor, and an orientation of the generated magnetic field; said control signals comprise a first control signal configured to cause said field angle to have a predetermined value, and a second control signal configured to cause said magnetic field to have a predetermined magnitude; and said controller is configured to vary said first and second control signals based upon said target position and said output of said sensor. said control signals for the stepper motor are arranged to cause a magnetic field to be generated by windings of the stepper motor, a field angle being defined between an angular position of the output shaft of the stepper motor, and an orientation of the generated magnetic field; said control signals comprise a first control signal configured to cause said field angle to have a predetermined value, and a second control signal configured to cause said magnetic field to have a predetermined magnitude; and said controller is configured to vary said first and second control signals based upon said target position and said output of said sensor.
Use of an inositol derivative, in which a monosaccharide or an oligosaccharide is bonded to inositol, for the non-therapeutic prevention or treatment of wrinkles, wherein a total amount of the monosaccharide or the oligosaccharide bonded to one inositol molecule is 2 or greater in terms of monosaccharide unit.