A drug delivery device (400, 600, 704, 904) comprising: a tip configured to be positioned in a nose of a patient, the tip having an opening therein; a coupling mechanism (410,602,710) configured to releasably couple to a first vial (100,702, 800,900) containing a first drug therein, to release the first vial therefrom, and to subsequently be releasably coupled to a second vial containing a second drug therein; a plunger configured to be actuated in a stroke direction through a first partial stroke and a second partial stroke to cause the first drug to exit through the opening, and to be subsequently actuated in the stroke direction through the first partial stroke and the second partial stroke to cause the second drug to exit through the opening; characterized in that the drug delivery device further comprises: a limiting device comprising: a one-piece stop body; a plurality of spring arms freely projecting in the stroke direction from the stop body and forming a component of the stop body; a stop formed by a circumferentially divided, radially inwardly projecting resilient collar, portions of which are in each case provided on each of the plurality of spring arms, the stop including a plurality of facing stop faces (436,454) in the form of an inner shoulder of the resilient collar; and wherein the stop face is configured such that in use a counter-stop defined by a proximal surface of the first or second vial at the end of the first partial stroke strikes against the stop face, so that a noticeable resistance is exerted against further operation of the device, and wherein the spring arms are configured to be forced outwards until they slide on the outer circumference of the first or second vial, thereby allowing the resistance to be overcome by a correspondingly more powerful actuation. a tip configured to be positioned in a nose of a patient, the tip having an opening therein; a coupling mechanism (410,602,710) configured to releasably couple to a first vial (100,702, 800,900) containing a first drug therein, to release the first vial therefrom, and to subsequently be releasably coupled to a second vial containing a second drug therein; a plunger configured to be actuated in a stroke direction through a first partial stroke and a second partial stroke to cause the first drug to exit through the opening, and to be subsequently actuated in the stroke direction through the first partial stroke and the second partial stroke to cause the second drug to exit through the opening; a limiting device comprising: a one-piece stop body; a plurality of spring arms freely projecting in the stroke direction from the stop body and forming a component of the stop body; a stop formed by a circumferentially divided, radially inwardly projecting resilient collar, portions of which are in each case provided on each of the plurality of spring arms, the stop including a plurality of facing stop faces (436,454) in the form of an inner shoulder of the resilient collar; and a one-piece stop body; a plurality of spring arms freely projecting in the stroke direction from the stop body and forming a component of the stop body; a stop formed by a circumferentially divided, radially inwardly projecting resilient collar, portions of which are in each case provided on each of the plurality of spring arms, the stop including a plurality of facing stop faces (436,454) in the form of an inner shoulder of the resilient collar; and wherein the stop face is configured such that in use a counter-stop defined by a proximal surface of the first or second vial at the end of the first partial stroke strikes against the stop face, so that a noticeable resistance is exerted against further operation of the device, and wherein the spring arms are configured to be forced outwards until they slide on the outer circumference of the first or second vial, thereby allowing the resistance to be overcome by a correspondingly more powerful actuation.