mhurhangee/ep-ind-claims huggingface dataset:
A method of forming capped nano-pillars on a substrate, the method comprising: forming a template on the substrate, the template defining nano-pores having a first width; partially filling the nano-pores to define nano-pillar stem portions of a first thickness corresponding to the first width; re-shaping the nano-pores to define re-shaped nano-pore sections having a second width different than the first width; at least partially filling the re-shaped nano-pore sections to define nano-pillar cap portions of a second thickness corresponding to the second width; and removing the template. forming a template on the substrate, the template defining nano-pores having a first width; partially filling the nano-pores to define nano-pillar stem portions of a first thickness corresponding to the first width; re-shaping the nano-pores to define re-shaped nano-pore sections having a second width different than the first width; at least partially filling the re-shaped nano-pore sections to define nano-pillar cap portions of a second thickness corresponding to the second width; and removing the template.
A control system for an electric machine comprising an inverter, a current sensor and a current controller, wherein the current controller comprises an input, an output, a threshold generator and a comparator, the current sensor outputs a voltage that is sensitive to current in the inverter, the output of the current sensor is delivered to the input of the current controller, and the current controller generates an overcurrent signal at the output whenever current in the inverter exceeds a current threshold, characterised in that the threshold generator stores a scaling factor and comprises a PWM module that operates on a reference voltage to generate a threshold voltage, the duty cycle of the PWM module is defined by the scaling factor, the comparator compares a voltage at the input against the threshold voltage and causes the overcurrent signal to be generated at the output when the voltage at the input exceeds the threshold voltage, and the scaling factor is set such that the effect of component tolerances on the current threshold is trimmed.
A method operative in a system utilizing a Request-to-Send/Clear-to-Send, RTS/CTS, protocol and that utilizes a plurality of channels for data transfer, comprising: sending, by a first device (100, 500), an RTS frame over the plurality of channels, wherein each device (120, 130, 140, 500) within a network that receives the RTS frame sets a network allocation vector, NAV, to a time duration that is based in part on information included in the RTS frame and that is computed based on a bandwidth of one of the plurality of channels and an amount of data to be sent by the first device (100, 500) to a second device (110, 500) over the bandwidth of the one of the plurality of channels; receiving, by the first device (100, 500), a CTS frame from the second device (110, 500) based on receipt of the RTS frame at the second device (110, 500), the CTS frame being received over at least one of the plurality of channels; transmitting, by the first device (100, 500), data to the second device (110, 500) within the time duration set by the NAV using the at least one of the plurality of channels over which the CTS frame has been received; and outputting, by the first device (100, 500), if the data transmission to the second device (110, 500) is completed, a data completion signal over the at least one of the plurality of channels over which the CTS frame has been received and which has been used for transmitting the data. sending, by a first device (100, 500), an RTS frame over the plurality of channels, wherein each device (120, 130, 140, 500) within a network that receives the RTS frame sets a network allocation vector, NAV, to a time duration that is based in part on information included in the RTS frame and that is computed based on a bandwidth of one of the plurality of channels and an amount of data to be sent by the first device (100, 500) to a second device (110, 500) over the bandwidth of the one of the plurality of channels; receiving, by the first device (100, 500), a CTS frame from the second device (110, 500) based on receipt of the RTS frame at the second device (110, 500), the CTS frame being received over at least one of the plurality of channels; transmitting, by the first device (100, 500), data to the second device (110, 500) within the time duration set by the NAV using the at least one of the plurality of channels over which the CTS frame has been received; and outputting, by the first device (100, 500), if the data transmission to the second device (110, 500) is completed, a data completion signal over the at least one of the plurality of channels over which the CTS frame has been received and which has been used for transmitting the data.
A cassette assembly attachable to an end portion of a waterborne vessel, the cassette assembly comprising: a cassette section to bear against an external structure in use, the cassette section movable relative to the vessel in a direction towards an opposite end of the vessel; and a resilient buffer system to counter movement of the cassette section when the vessel is moved towards the external structure, wherein the resilient buffer system comprises a fluid-operated buffer, characterised in that the cassette section is rotatable in a horizontal plane relative to the vessel. a cassette section to bear against an external structure in use, the cassette section movable relative to the vessel in a direction towards an opposite end of the vessel; and a resilient buffer system to counter movement of the cassette section when the vessel is moved towards the external structure, wherein the resilient buffer system comprises a fluid-operated buffer, characterised in that the cassette section is rotatable in a horizontal plane relative to the vessel.
A cover assembly for a Lithium-ion battery container, comprising: a cover for sealing a top opening of a battery container, said cover defining one or more openings for current collecting posts; a current collecting post extending through each opening and having a gap between the current collecting post and the cover; a top flange encircling each current collecting post, disposed to be opposed to and displaced from a top surface of said cover and extending radially outward from the current collecting post to beyond edges of the opening; a bottom flange encircling each current collecting post, disposed to be opposed to and displaced from a bottom surface of said cover and extending radially outward from the current collecting post to beyond edges of the opening; and a first polymer body for each current collecting post, wherein said first polymer body is continuous and extends to fill all gaps formed between any of the cover, current collecting post, top flange and bottom flange, and wherein said first polymer body is fused to the cover, current collector post, top flange and bottom flange where contacting same; the cover assembly characterized in that the cover further includes at least one of an electrolyte filling opening and a safety venting means, and the first polymer body is fused to same. a cover for sealing a top opening of a battery container, said cover defining one or more openings for current collecting posts; a current collecting post extending through each opening and having a gap between the current collecting post and the cover; a top flange encircling each current collecting post, disposed to be opposed to and displaced from a top surface of said cover and extending radially outward from the current collecting post to beyond edges of the opening; a bottom flange encircling each current collecting post, disposed to be opposed to and displaced from a bottom surface of said cover and extending radially outward from the current collecting post to beyond edges of the opening; and a first polymer body for each current collecting post, wherein said first polymer body is continuous and extends to fill all gaps formed between any of the cover, current collecting post, top flange and bottom flange, and wherein said first polymer body is fused to the cover, current collector post, top flange and bottom flange where contacting same; the cover assembly characterized in that the cover further includes at least one of an electrolyte filling opening and a safety venting means, and the first polymer body is fused to same.
A random access transmission apparatus, comprising: a controller configured to determine transmission power of a physical random access channel, PRACH, by estimating a pathloss based on a selected synchronization signal/physical broadcast channel block, SS/PBCH block, or a selected channel state information reference signal; and a transmitter configured to transmit a preamble via the PRACH at the determined transmission power, the controller is further configured to: calculate the transmission power using a first parameter; wherein, the first parameter comprises: a configuration parameter of a subcarrier spacing for the preamble transmission of a short sequence preamble, wherein the controller is further configured to calculate the transmission power according to a preamble receiving target power obtained based on a power offset and a power ramping counter, the power offset being set by the first parameter. a controller configured to determine transmission power of a physical random access channel, PRACH, by estimating a pathloss based on a selected synchronization signal/physical broadcast channel block, SS/PBCH block, or a selected channel state information reference signal; and a transmitter configured to transmit a preamble via the PRACH at the determined transmission power, the controller is further configured to: calculate the transmission power using a first parameter; wherein, the first parameter comprises: a configuration parameter of a subcarrier spacing for the preamble transmission of a short sequence preamble, wherein the controller is further configured to calculate the transmission power according to a preamble receiving target power obtained based on a power offset and a power ramping counter, the power offset being set by the first parameter.
A combination comprising (i) 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]-amino]-2-pyrimidinyl]-amino]-benzonitrile, also named TMC278, or a stereoisomeric form thereof; or a pharmaceutically acceptable salt thereof; and (ii) a nucleoside reverse transcriptase inhibitor and/or a nucleotide reverse transcriptase inhibitor; wherein TMC278 and the nucleotide reverse transcriptase inhibitor and the nucleoside reverse transcriptase inhibitor are therapeutically effective HIV inhibitors at a dose that can be administered once daily; for use in the treatment of HIV infection wherein the combination is administered once daily. (i) 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]-amino]-2-pyrimidinyl]-amino]-benzonitrile, also named TMC278, or a stereoisomeric form thereof; or a pharmaceutically acceptable salt thereof; and (ii) a nucleoside reverse transcriptase inhibitor and/or a nucleotide reverse transcriptase inhibitor; wherein TMC278 and the nucleotide reverse transcriptase inhibitor and the nucleoside reverse transcriptase inhibitor are therapeutically effective HIV inhibitors at a dose that can be administered once daily;
A compound for use in the treatment of a disease or condition selected from brain metastases from breast cancer, and brain metastases from non-brain cancers; the compound being of the formula: or a salt or tautomer thereof; wherein: X 1 is N or N + (O -); X 2 is N or CH; Q is selected from a C 1-3 alkylene group, cyclopropane-1,1-diyl and cyclobutane-1,1-diyl; R 1 is selected from hydrogen and C 1-4 alkyl; R 2, R 3 and R 4 are the same or different and each is selected from hydrogen and fluorine; Ar 1 is a benzene, thiophene, naphthyl or pyridine ring optionally substituted with 1, 2 or 3 substituents selected from fluorine; chlorine; bromine; C 1-4 hydrocarbyl; C 1-4 hydrocarbyloxy; trifluoromethyl; difluoromethyl; cyano; trifluoromethoxy; difluoromethoxy; Ar 2 is a monocyclic 5- or 6-membered heteroaryl ring containing 1, 2 or 3 heteroatom ring members selected from O, N and S and being optionally substituted with 1, 2 or 3 substituents selected from fluorine; C 1-4 hydrocarbyl; amino; mono-C 1-4 hydrocarbylamino and di-C 1-4 hydrocarbylamino; and wherein, in each substituent consisting of or containing C 1-4 hydrocarbyl, the C 1-4 hydrocarbyl is selected from C 1-4 alkyl, C 2-4 alkenyl, C 2-4 alkynyl, cyclopropyl, cyclobutyl and cyclopropylmethyl. X 1 is N or N + (O -); X 2 is N or CH; Q is selected from a C 1-3 alkylene group, cyclopropane-1,1-diyl and cyclobutane-1,1-diyl; R 1 is selected from hydrogen and C 1-4 alkyl; R 2, R 3 and R 4 are the same or different and each is selected from hydrogen and fluorine; Ar 1 is a benzene, thiophene, naphthyl or pyridine ring optionally substituted with 1, 2 or 3 substituents selected from fluorine; chlorine; bromine; C 1-4 hydrocarbyl; C 1-4 hydrocarbyloxy; trifluoromethyl; difluoromethyl; cyano; trifluoromethoxy; difluoromethoxy; Ar 2 is a monocyclic 5- or 6-membered heteroaryl ring containing 1, 2 or 3 heteroatom ring members selected from O, N and S and being optionally substituted with 1, 2 or 3 substituents selected from fluorine; C 1-4 hydrocarbyl; amino; mono-C 1-4 hydrocarbylamino and di-C 1-4 hydrocarbylamino; and wherein, in each substituent consisting of or containing C 1-4 hydrocarbyl, the C 1-4 hydrocarbyl is selected from C 1-4 alkyl, C 2-4 alkenyl, C 2-4 alkynyl, cyclopropyl, cyclobutyl and cyclopropylmethyl.
A method for producing at least one metabolite, peptide or recombinant protein of interest comprising the steps consisting in: a) culturing bacteria comprising: (i) a gene encoding said recombinant protein or at least one gene encoding an enzyme involved in the production of said peptide or metabolite, and (ii) genes encoding the ββ' subunits of a bacterial RNA polymerase operably linked to an inducible promoter, the natural promoter of said genes being replaced by said inducible promoter, in a first culture medium inducing the expression of the genes encoding said ββ' subunits, thereby inducing bacterial growth; b) culturing said bacteria in a second culture medium inhibiting the expression of the genes encoding said ββ' subunits and producing said metabolite, peptide or recombinant protein while inhibiting bacterial growth; c) optionally iterating steps a) and b) successively; and d) optionally recovering said metabolite, peptide or recombinant protein produced by said bacteria. a) culturing bacteria comprising: (i) a gene encoding said recombinant protein or at least one gene encoding an enzyme involved in the production of said peptide or metabolite, and (ii) genes encoding the ββ' subunits of a bacterial RNA polymerase operably linked to an inducible promoter, the natural promoter of said genes being replaced by said inducible promoter, in a first culture medium inducing the expression of the genes encoding said ββ' subunits, thereby inducing bacterial growth; (i) a gene encoding said recombinant protein or at least one gene encoding an enzyme involved in the production of said peptide or metabolite, and (ii) genes encoding the ββ' subunits of a bacterial RNA polymerase operably linked to an inducible promoter, the natural promoter of said genes being replaced by said inducible promoter, b) culturing said bacteria in a second culture medium inhibiting the expression of the genes encoding said ββ' subunits and producing said metabolite, peptide or recombinant protein while inhibiting bacterial growth; c) optionally iterating steps a) and b) successively; and d) optionally recovering said metabolite, peptide or recombinant protein produced by said bacteria.
Conveyor drum in the tobacco processing industry having a drum body comprising an external face and an internal face and at least one blade body disposed on the external face of the drum body, and a clamping device (122, 124) for the blade body acting on the internal face of the drum body remote from the external face of the drum body is provided to create a tensioning force directed radially inwards, and the drum body is provided with at least one connecting passage for the clamping device (122, 124) disposed radially between the internal face and a seat for a blade body in order to accommodate a clamping bolt of the clamping device (122, 124), characterised in that the seat having a pressing surface for a blade body and a wall surface lying opposite the pressing surface is provided on the drum body, preferably between two supporting bodies for material strip segments, and the clamping device (122, 124) comprises a clamping body, in particular a clamping bar, lying in contact with the wall surface and with a surface of the blade body facing the wall surface.
A method for manufacturing a built-up object, wherein the built-up object is a rotary member to be provided in a fluid machine and the built-up object includes a plurality of blades provided around a shaft body at circumferential intervals, and concave portions provided between adjacent ones of the blades, each of the concave portions having a curved shape in a section perpendicular to an axial direction, the method comprising: a selecting step of selecting a base material having a circular shape in a sectional view so that the base material has a larger radius than a bottom portion circle passing through bottom portions of the concave portions of the built-up object to be built, a building step of depositing weld beads obtained by melting and solidifying a filler material on a circumferential surface of the base material, thereby forming built-up portions to serve as the blades; and a cutting step of cutting parts of surfaces of the built-up portions and the circumferential surface of the base material, thereby forming the blades and the concave portions between the blades, satisfying T ≥ 1 / 2 H wherein H designates a height of the weld beads, and T designates a maximum cutting dimension in a radial direction of the base material. a selecting step of selecting a base material having a circular shape in a sectional view so that the base material has a larger radius than a bottom portion circle passing through bottom portions of the concave portions of the built-up object to be built, a building step of depositing weld beads obtained by melting and solidifying a filler material on a circumferential surface of the base material, thereby forming built-up portions to serve as the blades; and a cutting step of cutting parts of surfaces of the built-up portions and the circumferential surface of the base material, thereby forming the blades and the concave portions between the blades, satisfying T ≥ 1 / 2 H wherein H designates a height of the weld beads, and T designates a maximum cutting dimension in a radial direction of the base material.
An adeno-associated virus serotype 4 capsid protein selected from the group consisting of: i) an AAV4 capsid protein of SEQ ID NO:1 which is modified, wherein the modifications consist of: K492E, and K503E and modifications selected from one of the following groups (a) through (e): (a) N585S, T590V, D592R, R593G, and T595R; (b) N585S, T590V, D592N, and T595S; (c) N585S, T590P, D592M, R593G, and T595G; (d) N585R; S586V, N587D, and L588R; and (e) N585R; S586A, N587L, and L588R; wherein the numbering of the residues is based on the amino acid sequence of SEQ ID NO:1; and ii) an AAV4 capsid protein of SEQ ID NO:2 which is modified, wherein the modifications consist of: K493E, and K504E and modifications selected from one of the following groups (a) through (e): (a) N586S, T591V, D593R, R594G, and T596R; (b) N586S, T591V, D593N, and T596S; (c) N586S, T591P, D593M, R594G, and T596G; (d) N586R; S587V, N588D, and L589R; and (e) N586R; S587A, N588L, and L589R; wherein the numbering of the residues is based on the amino acid sequence of SEQ ID NO:2. i) an AAV4 capsid protein of SEQ ID NO:1 which is modified, wherein the modifications consist of: K492E, and K503E and modifications selected from one of the following groups (a) through (e): (a) N585S, T590V, D592R, R593G, and T595R; (b) N585S, T590V, D592N, and T595S; (c) N585S, T590P, D592M, R593G, and T595G; (d) N585R; S586V, N587D, and L588R; and (e) N585R; S586A, N587L, and L588R; wherein the numbering of the residues is based on the amino acid sequence of SEQ ID NO:1; and (a) N585S, T590V, D592R, R593G, and T595R; (b) N585S, T590V, D592N, and T595S; (c) N585S, T590P, D592M, R593G, and T595G; (d) N585R; S586V, N587D, and L588R; and (e) N585R; S586A, N587L, and L588R; ii) an AAV4 capsid protein of SEQ ID NO:2 which is modified, wherein the modifications consist of: K493E, and K504E and modifications selected from one of the following groups (a) through (e): (a) N586S, T591V, D593R, R594G, and T596R; (b) N586S, T591V, D593N, and T596S; (c) N586S, T591P, D593M, R594G, and T596G; (d) N586R; S587V, N588D, and L589R; and (e) N586R; S587A, N588L, and L589R; wherein the numbering of the residues is based on the amino acid sequence of SEQ ID NO:2. (a) N586S, T591V, D593R, R594G, and T596R; (b) N586S, T591V, D593N, and T596S; (c) N586S, T591P, D593M, R594G, and T596G; (d) N586R; S587V, N588D, and L589R; and (e) N586R; S587A, N588L, and L589R;
A method for producing a customized article of footwear, comprising the step of: receiving a customized three-dimensional footwear representation including a customized design having a background color and a design from a customer; converting the customized footwear representation into a set of two-dimensional portions (1186, 1188, 1190, 1192, 1194), the set including a first two-dimensional portion; associating each two-dimensional portion (1186, 1188, 1190, 1192, 1194) with a portion of a sheet material; printing substantially the entire area of the first two-dimensional portion, including the background color and the design to the first two-dimensional portion; cutting the first two-dimensional portion out of the sheet material; and assembling the first two-dimensional portion with a second two-dimensional portion. receiving a customized three-dimensional footwear representation including a customized design having a background color and a design from a customer; converting the customized footwear representation into a set of two-dimensional portions (1186, 1188, 1190, 1192, 1194), the set including a first two-dimensional portion; associating each two-dimensional portion (1186, 1188, 1190, 1192, 1194) with a portion of a sheet material; printing substantially the entire area of the first two-dimensional portion, including the background color and the design to the first two-dimensional portion; cutting the first two-dimensional portion out of the sheet material; and assembling the first two-dimensional portion with a second two-dimensional portion.
An organic electroluminescence device comprising a pair of electrodes and one or more organic layers including an emitting layer between the pair of electrodes, wherein one of the organic layer (s) comprises electron transporting compound having a structure of Formula (a) below and an emitting compound; wherein R 1 to R 15 are each independently a hydrogen atom, a halogen atom, a cyano group, an amino group, a C1-12 alkyl group, a C1-12 alkoxy group, an aryloxy group, an aryl group or a heterocyclic group, and neighboring substituent groups of R 1 to R 15 that are on the same phenyl group may be bonded together to form a condensed ring; and characterized in that said organic layer further comprises a hole transporting compound having 4 to 8 arylamine structures in the molecule and a molecular weight in the range of 800 to 5000.