mhurhangee/ep-ind-claims huggingface dataset:
A cell culture device for culturing a cell by using a culture medium, the device comprising: a first module including multiple bags having the culture medium and the cell, and a first flow channel group that supplies the culture medium and the cell from some of the multiple bags and exhausts the culture medium and the cell to some other bags of the multiple bags; a second module including a culture vessel for culturing the cell, and a second flow channel group that supplies the culture medium and the cell to the culture vessel and exhausts the culture medium and the cell from the culture vessel; a tank unit including an injection tank that holds the culture medium and the cell supplied from a flow channel in the first flow channel group, and allows the held culture medium and the cell to flow out to a flow channel in the second flow channel group in order to supply the culture medium and the cell to the culture vessel, and a waste tank that holds the culture medium and the cell, which are exhausted from the culture vessel and flown from the flow channel in the second flow channel group, and allows the held culture medium and the cell to flow out to the flow channel in the first flow channel group in order to exhaust the culture medium and the cell to some other bags of the multiple bags, and a third module including a pump unit that controls a volume of the supplied culture medium and the cell in the flow channels in the first and second flow channel groups and a volume of the culture medium and the cell held in the tank unit. a first module including multiple bags having the culture medium and the cell, and a first flow channel group that supplies the culture medium and the cell from some of the multiple bags and exhausts the culture medium and the cell to some other bags of the multiple bags; a second module including a culture vessel for culturing the cell, and a second flow channel group that supplies the culture medium and the cell to the culture vessel and exhausts the culture medium and the cell from the culture vessel; a tank unit including an injection tank that holds the culture medium and the cell supplied from a flow channel in the first flow channel group, and allows the held culture medium and the cell to flow out to a flow channel in the second flow channel group in order to supply the culture medium and the cell to the culture vessel, and a waste tank that holds the culture medium and the cell, which are exhausted from the culture vessel and flown from the flow channel in the second flow channel group, and allows the held culture medium and the cell to flow out to the flow channel in the first flow channel group in order to exhaust the culture medium and the cell to some other bags of the multiple bags, and a third module including a pump unit that controls a volume of the supplied culture medium and the cell in the flow channels in the first and second flow channel groups and a volume of the culture medium and the cell held in the tank unit.
A method of determining a phase-alignment between first and second clock signals of differing frequency, the method comprising the step of: sampling a value of the first clock signal at instants defined by an edge of the second clock signal; and characterised by further comprising the steps of: defining a sequence of the sampled values of the first clock signal, wherein consecutive sample values in the sequence are separated by N cycles of the second clock signal, and wherein N is an integer greater than 1; detecting the occurrence of a predetermined pattern of values in the defined sequence; and determining a phase-alignment between the first and second clock signals based on the detected occurrence of the predetermined pattern. sampling a value of the first clock signal at instants defined by an edge of the second clock signal; and characterised by further comprising the steps of: defining a sequence of the sampled values of the first clock signal, wherein consecutive sample values in the sequence are separated by N cycles of the second clock signal, and wherein N is an integer greater than 1; detecting the occurrence of a predetermined pattern of values in the defined sequence; and determining a phase-alignment between the first and second clock signals based on the detected occurrence of the predetermined pattern.
A self-crosslinking, polysiloxane-modified, polyhydroxy polyurethane resin characterized by having masked isocyanate groups in a structure of a polysiloxane-modified, polyhydroxy polyurethane resin derived from a reaction of a 5-membered cyclic carbonate compound and an amine-modified polysiloxane compound and having polysiloxane segments therein.
A method of removing casing from a well, in which an annulus between the outside of the casing and the inside of a surrounding downhole body is at least partially filled by a viscous and/or solid mass, the method comprising: (a) lowering a string into the well, a packer, a punch tool, and a cutting tool being connected to the string, and the string being arranged to carry a fluid; (b) locating an end of the string in relation to a plug in the casing, the plug providing a seal across the bore of the casing at a first depth; (c) forming one or more perforations through the casing with said punch tool at a second depth in the well, the second depth being shallower than the first depth; (d) setting the packer at a third depth, the third depth being shallower than the second depth; (e) pumping fluid through the string and through the one or more perforations; characterised in that: (f) a circulation test is performed by looking for a return at surface which determines if fluid has managed to pass through material in the annulus between the outside of the casing and the inside of the surrounding downhole body; (g) in the event that a return is detected at surface, cutting the casing using the cutting tool to separate a length of cut casing from plugged casing; and (h) pulling the length of cut casing from the well. (a) lowering a string into the well, a packer, a punch tool, and a cutting tool being connected to the string, and the string being arranged to carry a fluid; (b) locating an end of the string in relation to a plug in the casing, the plug providing a seal across the bore of the casing at a first depth; (c) forming one or more perforations through the casing with said punch tool at a second depth in the well, the second depth being shallower than the first depth; (d) setting the packer at a third depth, the third depth being shallower than the second depth; (e) pumping fluid through the string and through the one or more perforations; (f) a circulation test is performed by looking for a return at surface which determines if fluid has managed to pass through material in the annulus between the outside of the casing and the inside of the surrounding downhole body; (g) in the event that a return is detected at surface, cutting the casing using the cutting tool to separate a length of cut casing from plugged casing; and (h) pulling the length of cut casing from the well.
A modular orthosis (1, 1'), in particular for patients with osteoporosis, consisting of an orthopaedic garment (2, 2'), in particular an orthopaedically indicated undergarment (24, 24') which has a textile with various stretch zones (3, 4, 5, 6; 3', 4', 5', 6') for relieving and correcting the spine, wherein the stretch zones (3, 4, 5, 6; 3', 4', 5', 6') are designed in the form of integrated support strappings as two stretch zones (3, 4; 3', 4') encompassing the shoulders and two stretch zones (5, 6; 5', 6') encompassing the abdomen, and a splint, which is connectable to the garment (2, 2'), supports the spine, and, when the garment is worn, extends along the spine, wherein a belt system (8, 8') able to adjust the level of relief and correction of the spine is fastened to the garment (2, 2') and/or the splint.
A semiconductor device comprised of a single semiconductor chip, the semiconductor device comprising: a logic circuit having a predetermined function and comprising a second scan chain; a plurality of test points (TP1 to TPm) that include a test point flip-flop, wherein the test points (TP1 to TPm) are configured to fix a target node within the logic circuit to a predetermined logic level when the test point flip-flop holds a first value; a first scan chain configured by sequentially coupling each of the test point flip-flops; a failure injection circuit (ERINC1, ERINC2, ERINC3) that is configured to generate failure data; a mass-production test pattern generation circuit that is configured to generate a mass production test pattern and to input the mass production test pattern into the second scan chain; and a first selection circuit that is configured to select output data to the target node within the logic circuit between the failure data and the mass production test pattern and to inject the failure data or the mass production test pattern for performing a scan test of the logic circuit to the scan-in node of the first scan chain. a logic circuit having a predetermined function and comprising a second scan chain; a plurality of test points (TP1 to TPm) that include a test point flip-flop, wherein the test points (TP1 to TPm) are configured to fix a target node within the logic circuit to a predetermined logic level when the test point flip-flop holds a first value; a first scan chain configured by sequentially coupling each of the test point flip-flops; a failure injection circuit (ERINC1, ERINC2, ERINC3) that is configured to generate failure data; a mass-production test pattern generation circuit that is configured to generate a mass production test pattern and to input the mass production test pattern into the second scan chain; and a first selection circuit that is configured to select output data to the target node within the logic circuit between the failure data and the mass production test pattern and to inject the failure data or the mass production test pattern for performing a scan test of the logic circuit to the scan-in node of the first scan chain.
An in vitro method for predicting whether a patient with a cancer is likely to respond to an epidermal growth factor receptor (EGFR) inhibitor, which method comprises determining the expression level of hsa-miR-31-3p (SEQ ID NO:1) miRNA in a sample of said patient, wherein the lower the level of expression of the miRNA is, the more likely the patient is to respond to the EGFR inhibitor treatment, and wherein the cancer is selected from: • a KRAS wild-type colorectal cancer; and • a lung, breast, ovarian, endometrial, thyroid, nasopharynx, prostate, head and neck, kidney, pancreas, bladder, or brain cancer. • a KRAS wild-type colorectal cancer; and • a lung, breast, ovarian, endometrial, thyroid, nasopharynx, prostate, head and neck, kidney, pancreas, bladder, or brain cancer.
A material system, comprising: a first aluminum layer, the surfaces of which have undergone surface preparation to enhance bonding between the aluminum layer and other layers; a first glass composite layer adjacent to the first aluminum layer; and a first carbon composite layer adjacent to the first glass composite layer, and opposite to the first aluminum layer; wherein the first glass composite layer comprises a first thermoplastic resin, and wherein the first thermoplastic resin bonds the first aluminum layer and the first glass composite layer, wherein the first thermoplastic resin preferably bonds the first glass composite layer and the first carbon composite layer, wherein said thermoplastic resin has undergone a raising to a temperature sufficient to soften said aluminum layer which is greater than or equal to 316°C (600°F). a first aluminum layer, the surfaces of which have undergone surface preparation to enhance bonding between the aluminum layer and other layers; a first glass composite layer adjacent to the first aluminum layer; and a first carbon composite layer adjacent to the first glass composite layer, and opposite to the first aluminum layer; wherein the first glass composite layer comprises a first thermoplastic resin, and wherein the first thermoplastic resin bonds the first aluminum layer and the first glass composite layer, wherein the first thermoplastic resin preferably bonds the first glass composite layer and the first carbon composite layer, wherein said thermoplastic resin has undergone a raising to a temperature sufficient to soften said aluminum layer which is greater than or equal to 316°C (600°F).
A compound of Formula: or a pharmaceutically acceptable salt, solvate, ester or stereoisomer thereof, wherein: A at each occurrence is an anchoring group selected from the group consisting of zanamivir, laninamivir, oseltamivir, peramivir, and 2,3-difluoro sialic acids or an antibody binding domain which specifically binds neuraminidase; B is a multivalent backbone group selected from the group consisting of propane-1,2,3-tricarboxylate, prop-1-ene-1,2,3-tricarboxylate, cyclopropane-1,2,3-tricarboxylate, cyclohexane-1,3,5-tricarboxylate, benzene-1,3,5-tricarboxylate, methane tetracarboxylate, 1,2,3,4-butane tetracarboxylate, ethylene-1,1,2,2-tetracarboxylate, cyclohexane-1,2,4,5-tetracarboxylate, and benzene-1,2,4,5-tetracarboxylate; C at each occurrence is an anionic group of formula VIII: wherein R 4 at each occurrence is independently selected from the group consisting of - COOH, -SO 3 H, -NHCH 2 SO 3 H, -CONH-Cya, -CONH-Asp, -CONH-Asp(-NHCH 2 SO 3 H) w, and -CONH-Asp(-NHCH 2 PO 3 H) w, wherein w is an integer 1 or 2; R 5 is selected from the group consisting of -OH and -NHCH 2 SO 3 H u is an integer from 0 to 3; t is an integer from 0 to 3; r is an integer from 0 to 6; v is an integer from 1 to 12; L 1 and L 2 at each occurrence are divalent linkers; n is 2 or 3; and p is an integer from 1 to 3. A at each occurrence is an anchoring group selected from the group consisting of zanamivir, laninamivir, oseltamivir, peramivir, and 2,3-difluoro sialic acids or an antibody binding domain which specifically binds neuraminidase; B is a multivalent backbone group selected from the group consisting of propane-1,2,3-tricarboxylate, prop-1-ene-1,2,3-tricarboxylate, cyclopropane-1,2,3-tricarboxylate, cyclohexane-1,3,5-tricarboxylate, benzene-1,3,5-tricarboxylate, methane tetracarboxylate, 1,2,3,4-butane tetracarboxylate, ethylene-1,1,2,2-tetracarboxylate, cyclohexane-1,2,4,5-tetracarboxylate, and benzene-1,2,4,5-tetracarboxylate; C at each occurrence is an anionic group of formula VIII: wherein R 4 at each occurrence is independently selected from the group consisting of - COOH, -SO 3 H, -NHCH 2 SO 3 H, -CONH-Cya, -CONH-Asp, -CONH-Asp(-NHCH 2 SO 3 H) w, and -CONH-Asp(-NHCH 2 PO 3 H) w, wherein w is an integer 1 or 2; R 5 is selected from the group consisting of -OH and -NHCH 2 SO 3 H u is an integer from 0 to 3; t is an integer from 0 to 3; r is an integer from 0 to 6; v is an integer from 1 to 12; L 1 and L 2 at each occurrence are divalent linkers; n is 2 or 3; and p is an integer from 1 to 3. R 4 at each occurrence is independently selected from the group consisting of - COOH, -SO 3 H, -NHCH 2 SO 3 H, -CONH-Cya, -CONH-Asp, -CONH-Asp(-NHCH 2 SO 3 H) w, and -CONH-Asp(-NHCH 2 PO 3 H) w, wherein w is an integer 1 or 2; R 5 is selected from the group consisting of -OH and -NHCH 2 SO 3 H u is an integer from 0 to 3; t is an integer from 0 to 3; r is an integer from 0 to 6; v is an integer from 1 to 12; L 1 and L 2 at each occurrence are divalent linkers; n is 2 or 3; and p is an integer from 1 to 3.
A method comprising: detecting when one or more geo-fence events occur for a computing device during a conservation period of an operating system during which certain programs are not scheduled to run; maintaining a record of geo-fence events for each of multiple geo-fences; providing, to a program associated with at least one of the multiple geo-fences when the program is scheduled to run during an execution period of the operating system, an indication of one or more geo-fence events for the at least one of the multiple geo-fences from the record of geo-fence events; and characterized in by automatically deleting one of the multiple geo-fences associated with the program once expired, without notifying the program to delete the one of the multiple geo-fences. detecting when one or more geo-fence events occur for a computing device during a conservation period of an operating system during which certain programs are not scheduled to run; maintaining a record of geo-fence events for each of multiple geo-fences; providing, to a program associated with at least one of the multiple geo-fences when the program is scheduled to run during an execution period of the operating system, an indication of one or more geo-fence events for the at least one of the multiple geo-fences from the record of geo-fence events; and characterized in by
A radio resource scheduling method to be executed by a radio base station, wherein the radio resource scheduling method comprises: generating format information, wherein the format information specifies a format of resource allocation information, the format depending on a number of a plurality of mobile stations that simultaneously perform communication with the radio base station; generating the resource allocation information provided with the format specified by the format information corresponding to radio resources allocated to the plurality of mobile stations; and transmitting, to the plurality of mobile stations, the format information and the resource allocation information, wherein the generating the format information includes generating the format information specifying a first format when a maximum number of the plurality of mobile stations that simultaneously perform the communication with the radio base station is less than or equal to a first threshold value; and generating the format information specifying a second format when the maximum number of the plurality of mobile stations that simultaneously perform the communication with the radio base station is greater than the first threshold value and less than or equal to a second threshold value. generating format information, wherein the format information specifies a format of resource allocation information, the format depending on a number of a plurality of mobile stations that simultaneously perform communication with the radio base station; generating the resource allocation information provided with the format specified by the format information corresponding to radio resources allocated to the plurality of mobile stations; and transmitting, to the plurality of mobile stations, the format information and the resource allocation information, wherein the generating the format information includes generating the format information specifying a first format when a maximum number of the plurality of mobile stations that simultaneously perform the communication with the radio base station is less than or equal to a first threshold value; and generating the format information specifying a second format when the maximum number of the plurality of mobile stations that simultaneously perform the communication with the radio base station is greater than the first threshold value and less than or equal to a second threshold value.
A hair care composition comprising: (a) from 1% to 2% of a calcium chelant by weight of the hair care composition, wherein the calcium chelant comprises methylglycinediacetic acid (MGDA), wherein the total amount of calcium chelant ranges from 1% to 2% by weight of the hair care composition, wherein the calcium chelant is selected from the group consisting of diethylenetriaminepentaacetic acid (DTPA), hydroxyethyl ethylenediamine triacetic acid (HEDTA), methylglycinediacetic acid (MGDA), N-(2-acetamido)iminodiacetic acid, N(2-hydroxyethylimino)diacetic acid (HIDA), etidronic acid, pyrophosphoric acid, neridronic acid, aledronic acid, diethylenetriamine penta(methylene phosphonic acid) (DTPMP), 2-pyridinol-1- oxide (HPNO) hinokitiol, octopirox, and mixtures thereof; (b) from 5% to 20% of an anionic surfactant by weight of the hair care composition; (c) from 0.1 % to 5% of a hydrotrope by weight of the hair care composition; and (d) from 45% to 95% of a carrier by weight of the hair care composition, wherein the pH of the hair care composition is from 4 to 7. (a) from 1% to 2% of a calcium chelant by weight of the hair care composition, wherein the calcium chelant comprises methylglycinediacetic acid (MGDA), wherein the total amount of calcium chelant ranges from 1% to 2% by weight of the hair care composition, wherein the calcium chelant is selected from the group consisting of diethylenetriaminepentaacetic acid (DTPA), hydroxyethyl ethylenediamine triacetic acid (HEDTA), methylglycinediacetic acid (MGDA), N-(2-acetamido)iminodiacetic acid, N(2-hydroxyethylimino)diacetic acid (HIDA), etidronic acid, pyrophosphoric acid, neridronic acid, aledronic acid, diethylenetriamine penta(methylene phosphonic acid) (DTPMP), 2-pyridinol-1- oxide (HPNO) hinokitiol, octopirox, and mixtures thereof; (b) from 5% to 20% of an anionic surfactant by weight of the hair care composition; (c) from 0.1 % to 5% of a hydrotrope by weight of the hair care composition; and (d) from 45% to 95% of a carrier by weight of the hair care composition,
A method for detecting and tracking human activities in the vicinity of a robot, the method comprising: combining one or more two-dimensional images obtained from a time-of-flight (ToF) sensor with contemporaneously obtained data from a radar sensor, to obtain fused sensor data; detecting the presence of a human in the vicinity of the robot, based on the fused sensor data; and estimating direction of motion and speed of motion of the human, based on the fused sensor data, wherein said detecting and estimating are performed using a machine-learning model, the machine-learning model having been trained using two-dimensional ToF images and radar sensor data representative of an environment for the robot; and aligning velocity and/or range data obtained from the radar sensor with depth and/or amplitude data in the two-dimensional images, for input into the machine learning model; and filtering the velocity and/or range data and the depth and/or amplitude data, to detect distinct features in the combined data, prior to said detecting and estimating. combining one or more two-dimensional images obtained from a time-of-flight (ToF) sensor with contemporaneously obtained data from a radar sensor, to obtain fused sensor data; detecting the presence of a human in the vicinity of the robot, based on the fused sensor data; and estimating direction of motion and speed of motion of the human, based on the fused sensor data, wherein said detecting and estimating are performed using a machine-learning model, the machine-learning model having been trained using two-dimensional ToF images and radar sensor data representative of an environment for the robot; and aligning velocity and/or range data obtained from the radar sensor with depth and/or amplitude data in the two-dimensional images, for input into the machine learning model; and filtering the velocity and/or range data and the depth and/or amplitude data, to detect distinct features in the combined data, prior to said detecting and estimating.