mhurhangee/ep-ind-claims huggingface dataset:
A process for preparing a compound of formula I: wherein R 2 is hydrogen or an amine protecting group, comprising: (a) carbon-nitrogen cross-coupling of (i) an indazole of formula II containing a protected amide: wherein R 1 is C 1-8 alkyl, C 3-8 cycloalkyl, C 4-8 heterocyclyl, aryl, heteroaryl or arylC 1-8 alkyl, optionally substituted with one to three aryl, heteroaryl, C 3-8 cycloalkyl or OC 1-8 alkyl; and (ii) a piperidine compound of formula III: wherein R 3 is a leaving group and R 2 is as provided above; in the presence of a catalytic amount of a copper salt, a suitable ligand, a base, and a solvent, forming a compound of formula IV: wherein R 1 and R 2 are as provided above; and, (b) de-protecting the amide of the compound of formula IV. (a) carbon-nitrogen cross-coupling of (i) an indazole of formula II containing a protected amide: wherein R 1 is C 1-8 alkyl, C 3-8 cycloalkyl, C 4-8 heterocyclyl, aryl, heteroaryl or arylC 1-8 alkyl, optionally substituted with one to three aryl, heteroaryl, C 3-8 cycloalkyl or OC 1-8 alkyl; and (ii) a piperidine compound of formula III: wherein R 3 is a leaving group and R 2 is as provided above; in the presence of a catalytic amount of a copper salt, a suitable ligand, a base, and a solvent, forming a compound of formula IV: wherein R 1 and R 2 are as provided above; and, (b) de-protecting the amide of the compound of formula IV.
An influx chamber for an exhaust-gas catalytic converter, comprising: - a cylindrical housing having a side face and two front faces (32, 33), the side face and a first front face being made from a material impermeable to exhaust gases, and a second front face being at least partially permeable to exhaust gases, and the side face including an inlet opening for exhaust gases loaded with a reducing agent; and - a baffle positioned in the cylindrical housing and made from a material impermeable for exhaust gases, the baffle extending from the second front face of the housing towards the first front face of the housing, and the baffle including, along its longitudinal direction, a cone section where it forms the side face of a truncated cone, the cover face of which faces the first front face of the housing, and which extends over at least 90°, and in particular at least 135°, and further in particular more than 180° along the circumferential direction of the housing; characterized in that the cone section of the baffle extends along the circumferential direction of the housing over less than 330°, and in particular over less than 300°, and further in particular over less than 270°. - a cylindrical housing having a side face and two front faces (32, 33), the side face and a first front face being made from a material impermeable to exhaust gases, and a second front face being at least partially permeable to exhaust gases, and the side face including an inlet opening for exhaust gases loaded with a reducing agent; and - a baffle positioned in the cylindrical housing and made from a material impermeable for exhaust gases, the baffle extending from the second front face of the housing towards the first front face of the housing, and the baffle including, along its longitudinal direction, a cone section where it forms the side face of a truncated cone, the cover face of which faces the first front face of the housing, and which extends over at least 90°, and in particular at least 135°, and further in particular more than 180° along the circumferential direction of the housing; characterized in that
Heat exchange device able to work as a pulsating heat pipe comprising a plurality of pipes to provide fluid paths between a first fluid distribution element and a second fluid distribution element of the heat exchange device, wherein each pipe of the plurality of pipes comprises a group of channels, wherein each of the first fluid distribution element and the second fluid distribution element comprises at least a plate of a first type, and wherein each plate of the first type comprises openings for providing an alignment functionality for the plurality of pipes, and wherein the first fluid distribution element comprises a plate of a second type, and wherein the plate of the second type comprises openings for providing fluid paths between the plurality of pipes, and wherein the plate of the second type is positioned on a side of the plate of the first type of plates of the first fluid distribution element that is opposite to the second fluid distribution element, characterized in that the plates of the first type have a thickness that is identical of the thickness of the plate of the second type, the thickness of the plates of the first and second type being identical to the thickness of said pipes, wherein the thickness of a pipe is defined as a width of a pipe, wherein the width of the pipe is orthogonal both to a stacking direction of channels of the pipe and a fluid path direction of the pipe.
A layer element, wherein said layer element is a multilayer element, which comprises at least one layer comprising a polypropylene composition, which comprises - 5 to 50 wt% of a heterophasic copolymer of propylene which has a Melting temperature (Tm) of at least 145°C, when measured as described in the specification under the Determination methods, and a Vicat softening temperature (Vicat A) of at least 90°C (according to ASTM D 1525, method A, 50°C/h, 10N), and which comprises a polypropylene matrix component and an elastomeric propylene copolymer component which is dispersed in said polypropylene matrix, and - 20 to 60 wt% of a heterophasic copolymer of propylene which has a Melting temperature (Tm) of at least 145°C, when measured as described in the specification under the Determination methods, and a Vicat softening temperature (Vicat A) of at least 90°C (according to ASTM D 1525, method A, 50°C/h, 10N), and which comprises a polypropylene matrix component and an elastomeric propylene copolymer component which is dispersed in said polypropylene matrix, - 10 to 40 wt% of an inorganic filler, - 0 to 30 wt% of an plastomer, and - 0.3 to 5 wt% of an additive(s) other than the inorganic filler, based on the total amount (100 wt%) of the polypropylene composition; wherein the XCS of heterophasic copolymer of propylene is higher than the XCS of heterophasic copolymer of propylene; wherein the layer element has a total thickness of 140 μm to 700 μm. - 5 to 50 wt% of a heterophasic copolymer of propylene which has a Melting temperature (Tm) of at least 145°C, when measured as described in the specification under the Determination methods, and a Vicat softening temperature (Vicat A) of at least 90°C (according to ASTM D 1525, method A, 50°C/h, 10N), and which comprises a polypropylene matrix component and an elastomeric propylene copolymer component which is dispersed in said polypropylene matrix, and - 20 to 60 wt% of a heterophasic copolymer of propylene which has a Melting temperature (Tm) of at least 145°C, when measured as described in the specification under the Determination methods, and a Vicat softening temperature (Vicat A) of at least 90°C (according to ASTM D 1525, method A, 50°C/h, 10N), and which comprises a polypropylene matrix component and an elastomeric propylene copolymer component which is dispersed in said polypropylene matrix, a polypropylene matrix component and an elastomeric propylene copolymer component which is dispersed in said polypropylene matrix, - 10 to 40 wt% of an inorganic filler, - 0 to 30 wt% of an plastomer, and - 0.3 to 5 wt% of an additive(s) other than the inorganic filler, wherein the XCS of heterophasic copolymer of propylene is higher than the XCS of heterophasic copolymer of propylene; wherein the layer element has a total thickness of 140 μm to 700 μm.
A split mini-louvered fin for a heat exchanger assembly, comprising: a planar portion having a louver segment defined between a pair of primary slits, wherein said louver segment includes at least one intermediate slit between said pair of primary slits, thereby splitting said louver segment into at least two mini-louvers (176, 178), wherein each of said mini-louvers (176, 178) includes a front edge and an opposite trailing edge, characterized in that wherein said mini-louvers (176, 178) partially overlap one another such that the rear edge of one mini-louver extends past the front edge of the other said mini-louver (176, 178). a planar portion having a louver segment defined between a pair of primary slits, wherein said louver segment includes at least one intermediate slit between said pair of primary slits, thereby splitting said louver segment into at least two mini-louvers (176, 178), each of said mini-louvers (176, 178) includes a front edge and an opposite trailing edge, characterized in that wherein said mini-louvers (176, 178) partially overlap one another such that the rear edge of one mini-louver extends past the front edge of the other said mini-louver (176, 178).
Connection element for a blood treatment device, in particular a dialysis machine, comprising an inlet line, for admitting a fluid into the connection element, an outlet line, for removing a fluid from the connection element, at least a first discharge line, for discharging a fluid from the connection element, characterized in that the first discharge line is formed in a subsection around the inlet line, and wherein the inlet line and the first discharge line are open to a first end section of the connection element, and the first end section is fluidically connected to the subsection. an inlet line, for admitting a fluid into the connection element, an outlet line, for removing a fluid from the connection element, at least a first discharge line, for discharging a fluid from the connection element, characterized in that the first discharge line is formed in a subsection around the inlet line, and wherein the inlet line and the first discharge line are open to a first end section of the connection element, and the first end section is fluidically connected to the subsection.
An ex vivo method of producing a labeled virus, comprising the steps: i) producing a virus labeled with an azide-modified fatty acid, an azide-modified carbohydrate, an azide-modified isoprenoid lipid, or a pharmaceutically acceptable salt thereof, the method comprising contacting a cell infected with the virus with the azide-modified fatty acid, the azide-modified carbohydrate, the azide-modified isoprenoid lipid, or pharmaceutically acceptable salt thereof so that the azide-modified fatty acid, the azide-modified carbohydrate, the azide-modified isoprenoid lipid, or pharmaceutically acceptable salt thereof enters the cell and is incorporated into a protein of the virus, thereby producing the labeled virus, and ii) coupling the labeled virus to an alkyne-labeled reporter molecule, wherein "azide-modified fatty acid" refers to a fatty acid that comprises an azido group and has the following formula, R-N 3 where R comprises a hydrocarbon chain with at least one carboxylic acid functional group; wherein the azide-modified carbohydrate refers to a carbohydrate that comprises an azido group and has the following formula, R-N 3 where R is a carbohydrate; and wherein the azide-modified isoprenoid lipid is an azido farnesyl diphosphate, an azido farnesyl alcohol, an azido geranylgeranyl diphosphate, or an azido geranylgeranyl alcohol. i) producing a virus labeled with an azide-modified fatty acid, an azide-modified carbohydrate, an azide-modified isoprenoid lipid, or a pharmaceutically acceptable salt thereof, the method comprising contacting a cell infected with the virus with the azide-modified fatty acid, the azide-modified carbohydrate, the azide-modified isoprenoid lipid, or pharmaceutically acceptable salt thereof so that the azide-modified fatty acid, the azide-modified carbohydrate, the azide-modified isoprenoid lipid, or pharmaceutically acceptable salt thereof enters the cell and is incorporated into a protein of the virus, thereby producing the labeled virus, and ii) coupling the labeled virus to an alkyne-labeled reporter molecule, wherein "azide-modified fatty acid" refers to a fatty acid that comprises an azido group and has the following formula, R-N 3 where R comprises a hydrocarbon chain with at least one carboxylic acid functional group; wherein the azide-modified carbohydrate refers to a carbohydrate that comprises an azido group and has the following formula, R-N 3 where R is a carbohydrate; and wherein the azide-modified isoprenoid lipid is an azido farnesyl diphosphate, an azido farnesyl alcohol, an azido geranylgeranyl diphosphate, or an azido geranylgeranyl alcohol.
A computer implemented method comprising, at an electronic device having an input interface and a display: receiving information indicating a current location of the electronic device relative to a location of at least one other electronic device (402, 403) from an imaging device located above the electronic device and the at least one other electronic device, wherein the imaging device is in a device that is separate from the electronic device and the at least one other electronic device (402, 403); displaying on the display a representation of said at least one other electronic device and its location relative to the location of the electronic device; receiving at said input interface a gesture in a direction of the displayed representation of said at least one other electronic device; and in response to the gesture, establishing a communication session with said at least one other electronic device. receiving information indicating a current location of the electronic device relative to a location of at least one other electronic device (402, 403) from an imaging device located above the electronic device and the at least one other electronic device, wherein the imaging device is in a device that is separate from the electronic device and the at least one other electronic device (402, 403); displaying on the display a representation of said at least one other electronic device and its location relative to the location of the electronic device; receiving at said input interface a gesture in a direction of the displayed representation of said at least one other electronic device; and in response to the gesture, establishing a communication session with said at least one other electronic device.
Steering column for a motor vehicle, comprising a supporting unit, which can be connected to the chassis of the motor vehicle, and an adjusting unit which is held on said supporting unit and which supports a steering spindle which serves for introducing a steering movement from a steering wheel into a steering system for transmitting the steering movement to a steerable wheel, wherein the adjusting unit is displaceable with respect to the supporting unit in the event of a crash, and wherein an energy absorption device is arranged between the supporting unit and the adjusting unit in order to absorb energy over the displacement path in the event of a crash, wherein the energy absorption device comprises a first sliding rail fixed to the adjusting unit and a second sliding rail fixed to the supporting unit, which sliding rails are guided on one another, characterized in that the first sliding rail comprises a C-shaped cross section and the second sliding rail comprises a C-shaped cross section, and one sliding rail (50, 52) is guided in the other sliding rail (52, 50), wherein a contact is established between the sliding rails (50, 52), and which sliding rails are displaceable with respect to one another by friction to absorb energy in the event of a crash.
A method comprising: providing a plurality of multimedia broadcast multicast services to be transmitted over a common area from a plurality of nodes; and characterised in that the method comprises: providing information relating to a quantity of data of each of said plurality of services individually to said plurality of nodes; wherein said information relating to a quantity of data comprises information relating to a total number of packets and a total number of octets of each of said plurality of services; wherein data for each of the multimedia broadcast multicast services is transmitted in bursts; wherein, for each multimedia broadcast multicast service, a timestamp is included in a header of a beginning of a burst; wherein a packet counter and an octet counter are included in each packet header for each multimedia broadcast multicast service; and wherein the packets are transmitted to said plurality of nodes. providing information relating to a quantity of data of each of said plurality of services individually to said plurality of nodes; wherein said information relating to a quantity of data comprises information relating to a total number of packets and a total number of octets of each of said plurality of services; wherein data for each of the multimedia broadcast multicast services is transmitted in bursts; wherein, for each multimedia broadcast multicast service, a timestamp is included in a header of a beginning of a burst; wherein a packet counter and an octet counter are included in each packet header for each multimedia broadcast multicast service; and wherein the packets are transmitted to said plurality of nodes.
A stimuli-responsive material characterized by comprising a stimuli-responsive polymer, fibers and water, wherein the fibers are dispersed as having a number average diameter of 1 to 900 nm (determined according to the method of the description), wherein the weight ratio (stimuli-responsive polymer/fiber) of the stimuli-responsive polymer to the fiber is 5 to 100, and the stimuli-responsive polymer or fiber has one or more basic chemical structures constituting a polymer, selected from the group consisting of lactic acid unit (-O-CH(CH 3)-CO-) in polylactic acid, propylene unit (-CH 2 -CH(CH 3)-) in polypropylene, terephthalic acid and ethylene glycol unit (-O-CO-C 6 H 6 -CO-O-CH 2 CH 2 -), glycol unit (-CH 2 CH 2 -O-) in polyethylene terephthalate, nylon 6 unit (-CH 2 CH 2 CH 2 CH 2 CH 2 -CO-NH-) amide unit (-CO-NH-) in nylon 6, glycol unit (-CH 2 CH 2 -O-) in polyethylene glycol, N-isopropyl acrylamide unit (-CH 2 CH(CO-NH-CH(CH 3) 2)-), amide unit (-CO-NH-) in poly(N-isopropyl acrylamide), glucose unit in cellulose, glucosamine unit and amide unit (-CO-NH-) in chitin.
A hand-operated strapping tool comprising: a compressed gas driven motor; a tensioning assembly coupled to the motor; an opening assembly coupled to the tensioning assembly and actuated by movement of a first piston disposed within a first piston chamber to unclamp the strap during a powered opening operation; and a weld plate assembly coupled to the motor, the weld plate assembly including an upper weld gripper, a lower weld gripper and a second piston disposed within a second piston chamber; wherein: the motor actuates the tensioning assembly to tension overlapping strap portions clamped by the tensioning assembly during a tensioning operation; the second piston is actuated to force the upper weld gripper against the lower weld gripper during a welding operation; and the opening assembly is actuated to unclamp the overlapping strap portions during a powered opening operation. a compressed gas driven motor; a tensioning assembly coupled to the motor; an opening assembly coupled to the tensioning assembly and actuated by movement of a first piston disposed within a first piston chamber to unclamp the strap during a powered opening operation; and a weld plate assembly coupled to the motor, the weld plate assembly including an upper weld gripper, a lower weld gripper and a second piston disposed within a second piston chamber; wherein: the motor actuates the tensioning assembly to tension overlapping strap portions clamped by the tensioning assembly during a tensioning operation; the second piston is actuated to force the upper weld gripper against the lower weld gripper during a welding operation; and the opening assembly is actuated to unclamp the overlapping strap portions during a powered opening operation. the motor actuates the tensioning assembly to tension overlapping strap portions clamped by the tensioning assembly during a tensioning operation; the second piston is actuated to force the upper weld gripper against the lower weld gripper during a welding operation; and the opening assembly is actuated to unclamp the overlapping strap portions during a powered opening operation.
A method for discovering at least one neighbor cell, the method being performed by a base station of a cell (900, 1550) and comprising: receiving, by the base station, first discovering resource configuration information from a master cell (950, 1500) for managing a group of cells including the cell and the at least one neighbor cell (930, 1560); and receiving, by the base station, a discovery signal from the at least one neighbor cell based on the first discovering resource configuration information, the method being characterized in that: the first discovering resource configuration information includes information indicating a first time resource for allowing the cell to receive the discovery signal through a first frequency band and information indicating a second time resource for allowing the cell to transmit downlink data to a user equipment, UE, through the first frequency band. receiving, by the base station, first discovering resource configuration information from a master cell (950, 1500) for managing a group of cells including the cell and the at least one neighbor cell (930, 1560); and receiving, by the base station, a discovery signal from the at least one neighbor cell based on the first discovering resource configuration information, the method being characterized in that: the first discovering resource configuration information includes information indicating a first time resource for allowing the cell to receive the discovery signal through a first frequency band and information indicating a second time resource for allowing the cell to transmit downlink data to a user equipment, UE, through the first frequency band.