A patient interface comprising: sealing means for providing a sealed contact with a user, wherein the sealing means includes a flexible first end portion including a patient contacting surface and a second end portion; supporting means for supporting the sealing means on a user; headgear attaching means for attaching a headgear to the supporting means; and adjusting means, operatively coupled to the sealing means and the supporting means, for adjusting the sealing means relative to the supporting means manually from a first position to a second position and maintaining the sealing means in the second position responsive to being adjusted; wherein the adjusting means comprises: a knob portion, which is rotatably secured within a recess provided in the supporting means, wherein the knob portion have threads provided on an interior surface of the knob portion; a barrel member having threads provided on an exterior surface of the barrel member which engage the threads of the knob portion; a stem that engages with the barrel member; wherein the patient interface is configured so that rotating the knob portion causes the barrel member also to rotate, wherein the knob portion and the barrel member are not displaced relative to the supporting means when they are rotated and the stem is displaced relative to the supporting means. sealing means for providing a sealed contact with a user, wherein the sealing means includes a flexible first end portion including a patient contacting surface and a second end portion; supporting means for supporting the sealing means on a user; headgear attaching means for attaching a headgear to the supporting means; and adjusting means, operatively coupled to the sealing means and the supporting means, for adjusting the sealing means relative to the supporting means manually from a first position to a second position and maintaining the sealing means in the second position responsive to being adjusted; wherein the adjusting means comprises: a knob portion, which is rotatably secured within a recess provided in the supporting means, wherein the knob portion have threads provided on an interior surface of the knob portion; a barrel member having threads provided on an exterior surface of the barrel member which engage the threads of the knob portion; a stem that engages with the barrel member; wherein the patient interface is configured so that rotating the knob portion causes the barrel member also to rotate, wherein the knob portion and the barrel member are not displaced relative to the supporting means when they are rotated and the stem is displaced relative to the supporting means. a knob portion, which is rotatably secured within a recess provided in the supporting means, wherein the knob portion have threads provided on an interior surface of the knob portion; a barrel member having threads provided on an exterior surface of the barrel member which engage the threads of the knob portion; a stem that engages with the barrel member; wherein the patient interface is configured so that rotating the knob portion causes the barrel member also to rotate, wherein the knob portion and the barrel member are not displaced relative to the supporting means when they are rotated and the stem is displaced relative to the supporting means.