Control device for a recuperative brake system of a vehicle, having: a motor- and hydraulics- actuation device by means of which, while taking into account at least one sensor signal which is made available by at least one vehicle-mounted sensor and relates to an activation intensity of activation of at least one input element, - a first setpoint variable, relating to a first setpoint engine braking torque which is to be applied by means of at least one electric motor of the brake system to at least one first wheel which is assigned to at least one first wheel brake cylinder of a first brake circuit the brake system, can be defined as being unequal to zero, and - a second setpoint variable relating to a second setpoint engine braking torque which is to be applied by means of at least one electric motor of the brake system to at least one second wheel which is assigned to at least one first wheel brake cylinder of a second brake circuit of the brake system, can be defined as being unequal to zero, and can be output to the at least one electric motor; characterized in that by means of the motor- and hydraulics- actuation device, while additionally taking into account at least the at least one sensor signal of the first setpoint variable, of the second setpoint variable and/or at least one variable derived therefrom, a closing signal can be output to an isolating valve by means of which the at least one first wheel brake cylinder of the first brake circuit is connected to a master brake cylinder of the brake system. a motor- and hydraulics- actuation device by means of which, while taking into account at least one sensor signal which is made available by at least one vehicle-mounted sensor and relates to an activation intensity of activation of at least one input element, - a first setpoint variable, relating to a first setpoint engine braking torque which is to be applied by means of at least one electric motor of the brake system to at least one first wheel which is assigned to at least one first wheel brake cylinder of a first brake circuit the brake system, can be defined as being unequal to zero, and - a second setpoint variable relating to a second setpoint engine braking torque which is to be applied by means of at least one electric motor of the brake system to at least one second wheel which is assigned to at least one first wheel brake cylinder of a second brake circuit of the brake system, can be defined as being unequal to zero, - a first setpoint variable, relating to a first setpoint engine braking torque which is to be applied by means of at least one electric motor of the brake system to at least one first wheel which is assigned to at least one first wheel brake cylinder of a first brake circuit the brake system, can be defined as being unequal to zero, and - a second setpoint variable relating to a second setpoint engine braking torque which is to be applied by means of at least one electric motor of the brake system to at least one second wheel which is assigned to at least one first wheel brake cylinder of a second brake circuit of the brake system, can be defined as being unequal to zero, and can be output to the at least one electric motor;