A system for controlling fluid flow to a patient through a fluid pathway comprising: a fluid port comprising: a fluid channel; a fluid inlet at a first end of the fluid channel configured to couple to an outlet of a manually administrable fluid source; and a fluid outlet at a second end of the fluid channel configured to deliver fluid from the manually administrable fluid source to a fluid pathway (204, 206) that provides fluid to a patient; at least one sensor (145, 148, 149) to characterize at least one attribute of the fluid from the manually administrable fluid source; a controller (125, 130) in communication with the at least one sensor that generates at least one operation modification signal in response to the characterized at least one attribute matching at least one condition specified by at least one rule; and a transmitter for wirelessly transmitting the operation modification signal to at least one flow control valve, the operation modification signal, when received by the at least one flow control valve, causing a change in a level of fluid flow restriction of fluid passing through the at least one flow control valve, characterized by a housing that encloses the fluid port, wherein the housing envelops at least a portion of each of the fluid channel, the fluid inlet, the fluid outlet, the at least one sensor, the controller, and the transmitter, wherein the flow control valve is physically separated from and external to the housing and positioned along the fluid pathway that provides fluid to the patient, wherein the housing is suspended from the fluid pathway, and wherein the at least one sensor is configured to automatically measure a withdrawn downstream fluid volume of the fluid downstream of the fluid inlet and still within the fluid pathway after fluid flow through the fluid pathway is stopped. a fluid port comprising: a fluid channel; a fluid inlet at a first end of the fluid channel configured to couple to an outlet of a manually administrable fluid source; and a fluid outlet at a second end of the fluid channel configured to deliver fluid from the manually administrable fluid source to a fluid pathway (204, 206) that provides fluid to a patient; a fluid channel; a fluid inlet at a first end of the fluid channel configured to couple to an outlet of a manually administrable fluid source; and a fluid outlet at a second end of the fluid channel configured to deliver fluid from the manually administrable fluid source to a fluid pathway (204, 206) that provides fluid to a patient; at least one sensor (145, 148, 149) to characterize at least one attribute of the fluid from the manually administrable fluid source; a controller (125, 130) in communication with the at least one sensor that generates at least one operation modification signal in response to the characterized at least one attribute matching at least one condition specified by at least one rule; and a transmitter for wirelessly transmitting the operation modification signal to at least one flow control valve, the operation modification signal, when received by the at least one flow control valve, causing a change in a level of fluid flow restriction of fluid passing through the at least one flow control valve, characterized by a housing that encloses the fluid port, wherein the housing envelops at least a portion of each of the fluid channel, the fluid inlet, the fluid outlet, the at least one sensor, the controller, and the transmitter, wherein the flow control valve is physically separated from and external to the housing and positioned along the fluid pathway that provides fluid to the patient, wherein the housing is suspended from the fluid pathway, and wherein the at least one sensor is configured to automatically measure a withdrawn downstream fluid volume of the fluid downstream of the fluid inlet and still within the fluid pathway after fluid flow through the fluid pathway is stopped.