A compound of the following structural formula, stereoisomers thereof, epimers thereof, configurational isomers thereof, or pharmaceutically acceptable salts thereof or hydrates thereof, wherein echinocystic acid is excluded: wherein dotted line represents optional, i.e., single or double bond; R1 is XR1', wherein X is O or NH, R1' is hydrogen, monosaccharides, disaccharides or derivatives thereof wherein the derivatives of monosaccharides or disaccharides refers to that one or more wherein 2, 3 or 4 hydroxy groups thereof can be substituted by substituents such as C1-C6 alkanoyloxy group, C1-C6 alkoxy, benzoyloxy, and/or benzyloxy, wherein the benzene ring may be substituted with one or more halogen, nitro, amino and/or C1-C6 alkyl groups; one of the hydroxyl groups can be substituted by hydrogen, amino group or an acetylamino group; R2 and R7 are each independently selected from the group consisting of H, halogen, hydroxy, cyano, nitro, mercapto, carbonyl, C1-C6 thioalkyl, C1-C6 alkyl group unsubstituted or substituted by a hydroxyl group, an amino group or a carboxyl group, amino, NR11'R12', wherein R11' and R12' are each independently selected from C1-C6 alkyl group unsubstituted or substituted by a hydroxyl group, an amino group or a carboxyl group; R3, R4, R5, R6 and R8 are each independently selected from the group consisting of H, C1-C6 alkyl group unsubstituted or substituted by a hydroxyl group, an amino group or a carboxyl group; R9 is selected from the group consisting of H, halogen, hydroxy, cyano, nitro, mercapto, C1-C6 thioalkyl group, a carbonyl group, an oxime group, C1-C6 alkyl group unsubstituted or substituted by a hydroxyl group, an amino group or a carboxyl group; R10, R11, R12, R13 and R14 are each independently selected from the group consisting of H, OH, NHR9'(wherein R9' is H, C1-C3 alkyl unsubstituted or substituted by hydroxyl, amino or carboxyl group), mercapto, C1-C6 thioalkyl, C1-C3 alkyl unsubstituted or substituted by hydroxyl, amino or carboxyl; provided that when R7 is hydroxyl, R2 and R1'are not hydrogen. dotted line represents optional, i.e., single or double bond; R1 is XR1', wherein X is O or NH, R1' is hydrogen, monosaccharides, disaccharides or derivatives thereof wherein the derivatives of monosaccharides or disaccharides refers to that one or more wherein 2, 3 or 4 hydroxy groups thereof can be substituted by substituents such as C1-C6 alkanoyloxy group, C1-C6 alkoxy, benzoyloxy, and/or benzyloxy, wherein the benzene ring may be substituted with one or more halogen, nitro, amino and/or C1-C6 alkyl groups; one of the hydroxyl groups can be substituted by hydrogen, amino group or an acetylamino group; R2 and R7 are each independently selected from the group consisting of H, halogen, hydroxy, cyano, nitro, mercapto, carbonyl, C1-C6 thioalkyl, C1-C6 alkyl group unsubstituted or substituted by a hydroxyl group, an amino group or a carboxyl group, amino, NR11'R12', wherein R11' and R12' are each independently selected from C1-C6 alkyl group unsubstituted or substituted by a hydroxyl group, an amino group or a carboxyl group; R3, R4, R5, R6 and R8 are each independently selected from the group consisting of H, C1-C6 alkyl group unsubstituted or substituted by a hydroxyl group, an amino group or a carboxyl group; R9 is selected from the group consisting of H, halogen, hydroxy, cyano, nitro, mercapto, C1-C6 thioalkyl group, a carbonyl group, an oxime group, C1-C6 alkyl group unsubstituted or substituted by a hydroxyl group, an amino group or a carboxyl group; R10, R11, R12, R13 and R14 are each independently selected from the group consisting of H, OH, NHR9'(wherein R9' is H, C1-C3 alkyl unsubstituted or substituted by hydroxyl, amino or carboxyl group), mercapto, C1-C6 thioalkyl, C1-C3 alkyl unsubstituted or substituted by hydroxyl, amino or carboxyl; provided that when R7 is hydroxyl, R2 and R1'are not hydrogen.