mhurhangee/ep-ind-claims huggingface dataset:
A method of monitoring an operation status of a confined laser cutting tool, the method comprising: forming a confining column with a nozzle in fluid communication with a reservoir of confining fluid; emitting light in the form of laser beams from a laser source; directing the emitted laser beams into the confining column comprised of the confining liquid to form a confined laser beam, the confined laser beam comprising the confining column and a portion of the laser beams confined therein; sensing a characteristic of the confined laser beam with a sensor; and characterized by the step of determining the operation status of the confined laser cutting tool based on the sensed characteristic of the confined laser beam, wherein the step of determining comprising determining a remaining usable life of the nozzle based on the sensed intensity, wherein the step of sensing comprises sensing an optical characteristic of the re-emitted light from the confined laser beam within a predetermined wavelength range, wherein the predetermined wavelength range includes approximately six hundred nanometers or greater, and the sensed optical characteristic of the re-emitted light from the confined laser beam comprises an intensity at a wavelength greater than about six hundred nanometers. forming a confining column with a nozzle in fluid communication with a reservoir of confining fluid; emitting light in the form of laser beams from a laser source; directing the emitted laser beams into the confining column comprised of the confining liquid to form a confined laser beam, the confined laser beam comprising the confining column and a portion of the laser beams confined therein; sensing a characteristic of the confined laser beam with a sensor; and characterized by the step of determining the operation status of the confined laser cutting tool based on the sensed characteristic of the confined laser beam, wherein the step of determining comprising determining a remaining usable life of the nozzle based on the sensed intensity, wherein the step of sensing comprises sensing an optical characteristic of the re-emitted light from the confined laser beam within a predetermined wavelength range, wherein the predetermined wavelength range includes approximately six hundred nanometers or greater, and the sensed optical characteristic of the re-emitted light from the confined laser beam comprises an intensity at a wavelength greater than about six hundred nanometers.
A heating tool comprising an exothermic composition containing a metal ion sequestrant, an oxidizable metal powder, a water-soluble salt, an oxidation accelerator and water, wherein at least the exothermic composition is housed in an air-permeable container bag, characterized in that the heating tool further comprises a fragrance, and wherein the oxidation accelerator has an iodine adsorption of not higher than 400 mg/g on average.
A method for determining a cause of a voltage drop load-side from a circuit breaker by means of an auxiliary unit, the load-side voltage drop corresponding to an opening of the circuit breaker or to a voltage drop at the input of the circuit breaker below a first reference voltage value, the circuit breaker being in an open position able to interrupt the flow of an electric current in an electric connection including at least one electric conductor (12, 14), the auxiliary unit comprising at least one current sensor able to measure the intensity of the current flowing in a respective electric conductor (12, 14) and a first detection means able to detect the voltage drop load-side from the circuit breaker, the method comprising the following steps: - a) measuring, with said or each current sensor, the intensity of the current flowing in said or each electric conductor (12, 14), - b) detecting, via the first detection means, the voltage drop load-side from the electric circuit breaker, the method being characterized in that it further comprises the following step: - c) determining (120, 122, 126, 128, 130), with the auxiliary unit and depending on the intensity measured by said or each current sensor, a cause of a detected voltage drop load-side from the circuit breaker, said cause being preferably selected from the group consisting in: an electric overload, a short-circuit and a voltage drop. - a) measuring, with said or each current sensor, the intensity of the current flowing in said or each electric conductor (12, 14), - b) detecting, via the first detection means, the voltage drop load-side from the electric circuit breaker, the method being characterized in that it further comprises the following step: - c) determining (120, 122, 126, 128, 130), with the auxiliary unit and depending on the intensity measured by said or each current sensor, a cause of a detected voltage drop load-side from the circuit breaker, said cause being preferably selected from the group consisting in: an electric overload, a short-circuit and a voltage drop.
A mobile communication system that includes terminals and a plurality of base stations (211, 212) that are adapted to use scrambling codes to carry out radio communication with said terminals, wherein each of said plurality of base stations (211, 212) is adapted to: transmit to neighboring base stations (211, 212) information of the range of uplink scrambling codes that are reserved in that base station (211, 212); and when determining the range of uplink scrambling codes that are to be reserved in their own station (211, 212), receive from neighboring base stations (211, 212) information of the range of uplink scrambling codes that are reserved in the neighboring base stations (211, 212). transmit to neighboring base stations (211, 212) information of the range of uplink scrambling codes that are reserved in that base station (211, 212); and when determining the range of uplink scrambling codes that are to be reserved in their own station (211, 212), receive from neighboring base stations (211, 212) information of the range of uplink scrambling codes that are reserved in the neighboring base stations (211, 212).
A vehicle-mountable child safety seat assembly, the seat assembly including a safety seat, and a prop assembly mounted with respect to the safety seat, the prop assembly having a stowed position and a safely deployed position, the prop assembly including: a leg assembly; a foot assembly mounted to the leg assembly; and a first sensor for sensing when the prop assembly is not in the stowed position; a second sensor for sensing when the prop assembly is not in the safely deployed position; a visual warning indicator, the visual warning indicator visually obscured when the prop assembly is in the safely deployed position; and a warning system having a standby state, a timing state and a warning state, wherein the warning system changes from the standby state to the timing state when the first sensor senses that the prop assembly is not in its stowed position, and wherein the warning system changes from the timing state to the warning state, if the second sensor senses that the prop assembly is not in its safely deployed position by a pre-determined time after the change from the standby state to the timing state. a leg assembly; a foot assembly mounted to the leg assembly; and a first sensor for sensing when the prop assembly is not in the stowed position; a second sensor for sensing when the prop assembly is not in the safely deployed position; a visual warning indicator, the visual warning indicator visually obscured when the prop assembly is in the safely deployed position; and a warning system having a standby state, a timing state and a warning state, wherein the warning system changes from the standby state to the timing state when the first sensor senses that the prop assembly is not in its stowed position, and wherein the warning system changes from the timing state to the warning state, if the second sensor senses that the prop assembly is not in its safely deployed position by a pre-determined time after the change from the standby state to the timing state.
Soil compactor, comprising: - at least one compactor roller (14, 16) which can be rotated about a roller rotary axis, - a fluid storing/dispensing system for storing and dispensing fluid to at least one compactor roller (14, 16), wherein the fluid storing/dispensing system comprises at least two fluid main reservoirs (24, 26) and in association to each fluid main reservoir (24, 26) one fluid main line (30, 32), characterized in that: fluid main lines (30, 32) of at least two fluid main reservoirs (24, 26) communicate with a common filling port for filling the associated fluid main reservoirs (24, 26). - at least one compactor roller (14, 16) which can be rotated about a roller rotary axis, - a fluid storing/dispensing system for storing and dispensing fluid to at least one compactor roller (14, 16), wherein the fluid storing/dispensing system comprises at least two fluid main reservoirs (24, 26) and in association to each fluid main reservoir (24, 26) one fluid main line (30, 32), characterized in that: fluid main lines (30, 32) of at least two fluid main reservoirs (24, 26) communicate with a common filling port for filling the associated fluid main reservoirs (24, 26).
Serum glucocorticoid induced kinase 1 inhibitor for use in a method of reducing cerebrospinal fluid production in a subject having hydrocephalus, wherein the SGK1 inhibitor is SI-113. for use in a method of reducing cerebrospinal fluid production in a subject having hydrocephalus, wherein the SGK1 inhibitor is SI-113.
A method of handling certificate validation, the method comprising: receiving a certificate validation command, the certificate validation command specifying a certificate and a certificate store of a plurality of certificate stores, each certificate store with a designation of a class identifying a mode of operation of a device; building a certificate chain for the certificate; attempting to validate the certificate chain to a root certification authority certificate in the respective certificate store; and replying to a source of the certificate validation command with an indication of validation status. receiving a certificate validation command, the certificate validation command specifying a certificate and a certificate store of a plurality of certificate stores, each certificate store with a designation of a class identifying a mode of operation of a device; building a certificate chain for the certificate; attempting to validate the certificate chain to a root certification authority certificate in the respective certificate store; and replying to a source of the certificate validation command with an indication of validation status.
An organic light-emitting device comprising: a first electrode; a second electrode; and an organic layer between the first electrode and the second electrode, the organic layer comprising an emission layer, wherein the emission layer comprises a condensed cyclic compound being one of Compounds 1-2 to 1-54 and 1-56 to 1-126 and a condensed cyclic compound represented by Formula -1: wherein, in Formula -1, m is one and (L 65) a65 does not exist, *-(L 61) a61 -(B 1), *-(L 62) a62 -(B 2), and *-(L 63) a63 -(B 3) in Formula -1 are each independently selected from the group represented by Formulae 7-1 to 7-29 and groups represented by Formulae 8-1 to 8-7: * indicates a binding site to a neighboring atom, wherein, in Formulae 7-1 to 7-29, Y 3 is O, S, C(Z 13)(Z 14), or N(Z 15), Z 13 to Z 15 are each independently selected from -CD 3, -CD 2 H, -CDH 2, a C 1 -C 20 alkyl group, a C 1 -C 20 alkoxy group, a phenyl group, and a biphenyl group. a first electrode; a second electrode; and an organic layer between the first electrode and the second electrode, the organic layer comprising an emission layer, wherein the emission layer comprises a condensed cyclic compound being one of Compounds 1-2 to 1-54 and 1-56 to 1-126 and a condensed cyclic compound represented by Formula -1: wherein, in Formula -1, m is one and (L 65) a65 does not exist, *-(L 61) a61 -(B 1), *-(L 62) a62 -(B 2), and *-(L 63) a63 -(B 3) in Formula -1 are each independently selected from the group represented by Formulae 7-1 to 7-29 and groups represented by Formulae 8-1 to 8-7: * indicates a binding site to a neighboring atom, wherein, in Formulae 7-1 to 7-29, Y 3 is O, S, C(Z 13)(Z 14), or N(Z 15), Z 13 to Z 15 are each independently selected from -CD 3, -CD 2 H, -CDH 2, a C 1 -C 20 alkyl group, a C 1 -C 20 alkoxy group, a phenyl group, and a biphenyl group. m is one and (L 65) a65 does not exist, *-(L 61) a61 -(B 1), *-(L 62) a62 -(B 2), and *-(L 63) a63 -(B 3) in Formula -1 are each independently selected from the group represented by Formulae 7-1 to 7-29 and groups represented by Formulae 8-1 to 8-7: * indicates a binding site to a neighboring atom, wherein, in Formulae 7-1 to 7-29, Y 3 is O, S, C(Z 13)(Z 14), or N(Z 15), Z 13 to Z 15 are each independently selected from -CD 3, -CD 2 H, -CDH 2, a C 1 -C 20 alkyl group, a C 1 -C 20 alkoxy group, a phenyl group, and a biphenyl group.
A trocar system comprising: a cannula; an obturator configured to be slid into and removed from the cannula, the obturator extending along an axis from a distal end to a proximal end, the obturator configured to be operably connected to an angled endoscope via a lumen defined by the obturator, the obturator comprising: a window at or near the distal end of the obturator; a prism which is removeably attached to the lumen defined by the obturator, the prism configured to bend light received through the window toward a light gathering element associated with the endoscope, wherein the prism is disposed at an angle such that the direction of travel of light is substantially perpendicular to the light gathering element, the light gathering element disposed at an angle relative to a plane extending transversely to the endoscope's axis; and retaining functionality configured to allow the prism to be one or both of: placed into the obturator to bend the light toward the light gathering element or attached to the obturator to bend the light toward the light gathering element. a cannula; an obturator configured to be slid into and removed from the cannula, the obturator extending along an axis from a distal end to a proximal end, the obturator configured to be operably connected to an angled endoscope via a lumen defined by the obturator, the obturator comprising: a window at or near the distal end of the obturator; a prism which is removeably attached to the lumen defined by the obturator, the prism configured to bend light received through the window toward a light gathering element associated with the endoscope, wherein the prism is disposed at an angle such that the direction of travel of light is substantially perpendicular to the light gathering element, the light gathering element disposed at an angle relative to a plane extending transversely to the endoscope's axis; and retaining functionality configured to allow the prism to be one or both of: placed into the obturator to bend the light toward the light gathering element or attached to the obturator to bend the light toward the light gathering element. a window at or near the distal end of the obturator; a prism which is removeably attached to the lumen defined by the obturator, the prism configured to bend light received through the window toward a light gathering element associated with the endoscope, wherein the prism is disposed at an angle such that the direction of travel of light is substantially perpendicular to the light gathering element, the light gathering element disposed at an angle relative to a plane extending transversely to the endoscope's axis; and retaining functionality configured to allow the prism to be one or both of: placed into the obturator to bend the light toward the light gathering element or attached to the obturator to bend the light toward the light gathering element.
A method for detecting a particulate substance by immunochromatography, the particulate substance comprising, on its surface, a plurality of substances to be bound containing a first substance to be bound and a second substance to be bound which may be the same or different with respect to each other, wherein the method comprises the steps of: contacting on a membrane a sample containing the particulate substance with a first specific binding substance for the first substance to be bound to capture the particulate substance with the first specific binding substance; contacting the captured particulate substance with a second specific binding substance for the second substance to be bound to label the particulate substance; and detecting the labeled particulate substance, wherein the first specific binding substance is immobilized on the membrane, and the second specific binding substance is bound to a labeling substance, and wherein the particulate substance is an extracellular vesicle. contacting on a membrane a sample containing the particulate substance with a first specific binding substance for the first substance to be bound to capture the particulate substance with the first specific binding substance; contacting the captured particulate substance with a second specific binding substance for the second substance to be bound to label the particulate substance; and detecting the labeled particulate substance, wherein the first specific binding substance is immobilized on the membrane, and the second specific binding substance is bound to a labeling substance, and wherein the particulate substance is an extracellular vesicle.
Rotating floating platform comprising: a central floating module, a plurality of propulsion modules coupled to the central floating module, said central floating module comprising a central floating component and an outer component of a ring shape, said central floating component being provided with a bearing type connection for coupling said outer component and means for fixating a mooring unit of an anchor type, said outer component providing the connection of the central floating module to said plurality of propulsion modules by means of a fixation mechanism; wherein each of said plurality of propulsion modules comprises at least one floating component and a motor unit coupled to said at least one floating component, the motor unit comprising a motor and a propeller; and a control unit comprising a processor and a communication module, wherein the communication module is configured to establish a wired/wireless communication link to an external entity, and the processor is configured to operate the motor and the propeller of the motor unit of each of said plurality of propulsion modules by defining a rotation movement according to instructions received by the external entity. a central floating module, a plurality of propulsion modules coupled to the central floating module, said central floating module comprising a central floating component and an outer component of a ring shape, said central floating component being provided with a bearing type connection for coupling said outer component and means for fixating a mooring unit of an anchor type, said outer component providing the connection of the central floating module to said plurality of propulsion modules by means of a fixation mechanism; wherein each of said plurality of propulsion modules comprises at least one floating component and a motor unit coupled to said at least one floating component, the motor unit comprising a motor and a propeller; and a control unit comprising a processor and a communication module, wherein the communication module is configured to establish a wired/wireless communication link to an external entity, and the processor is configured to operate the motor and the propeller of the motor unit of each of said plurality of propulsion modules by defining a rotation movement according to instructions received by the external entity.
A method of preparing a compound having formula: or a salt thereof, wherein R 1 is Cl or CF 3; R 2 is F or Cl; and R 3 is H or CH 3; and wherein said compound of formula is at least 95% free of enantiomeric or diastereomeric impurities, said method comprising: (a) contacting a compound having the formula (i-3): wherein R is selected from the group consisting of H, C 1-8 alkyl, aryl and aryl-C 1-4 alkyl, which is at least 95% free of enantiomeric or diastereomeric impurities, or a salt thereof, with a compound having the formula: wherein LG is a leaving group; R 2 is F or Cl; and R 3 is H or CH 3; under conditions sufficient to form a compound of formula (i-4): and (b) converting said compound of formula (i-4) to said compound of formula wherein said compound of formula is at least 95% free of enantiomeric or diastereomeric impurities. R 1 is Cl or CF 3; R 2 is F or Cl; and R 3 is H or CH 3; and wherein said compound of formula is at least 95% free of enantiomeric or diastereomeric impurities, said method comprising: (a) contacting a compound having the formula (i-3): wherein R is selected from the group consisting of H, C 1-8 alkyl, aryl and aryl-C 1-4 alkyl, which is at least 95% free of enantiomeric or diastereomeric impurities, or a salt thereof, with a compound having the formula: wherein LG is a leaving group; R 2 is F or Cl; and R 3 is H or CH 3; under conditions sufficient to form a compound of formula (i-4): and (b) converting said compound of formula (i-4) to said compound of formula wherein said compound of formula is at least 95% free of enantiomeric or diastereomeric impurities. (a) contacting a compound having the formula (i-3): wherein R is selected from the group consisting of H, C 1-8 alkyl, aryl and aryl-C 1-4 alkyl, which is at least 95% free of enantiomeric or diastereomeric impurities, or a salt thereof, with a compound having the formula: wherein LG is a leaving group; R 2 is F or Cl; and R 3 is H or CH 3; under conditions sufficient to form a compound of formula (i-4): and (b) converting said compound of formula (i-4) to said compound of formula wherein said compound of formula is at least 95% free of enantiomeric or diastereomeric impurities.
A nozzle for forming a container preform into a plastic container, the nozzle comprising: a first cylindrical portion including a first seal; a second cylindrical portion including a second seal; and a tapered portion between the first and second cylindrical portions. a first cylindrical portion including a first seal; a second cylindrical portion including a second seal; and a tapered portion between the first and second cylindrical portions.
An ex vivo method for editing the C9ORF72 gene in a human cell by genome editing comprising introducing into the cell one or more Cas9 endonucleases and one or more guide ribonucleic acids (gRNAs) to effect one or more single-strand breaks (SSBs) or double-strand breaks (DSBs) within or near the C9ORF72 gene or other DNA sequences that encode regulatory elements of the C9ORF72 gene that results in permanent deletion or correction of an expanded hexanucleotide repeat within or near the C9ORF72 gene and results in restoration of C9ORF72 protein activity, wherein the one or more gRNAs comprise a spacer sequence selected from the group consisting of SEQ ID NOs 2669, 2673, 2681, 2687, 2689, 2694, 2697, 2698, 2701, 2755, 2758, 2763, 2785, 2805, 3341, 3344, 3403, 3404, 3405, 3410, 3421, 3422, 3430, 3432, 3435, 3437, 3464, 3472, 3475, 3479, 3485, 3496, 3503, 3519, 3523, 3524, 3531, 3534, 3542, 3549, 3556, 3558, and 3592, and wherein the gRNAs induce a cutting efficiency of 80% or higher.
Flow meter for determining the flow rate of liquids with a viscosity of more than 30 mm 2 /s, with a housing, which comprises precisely one elongated cylindrical recess, with precisely one screw spindle, which comprises a longitudinal axis, wherein the screw spindle is arranged at least partially in the elongated cylindrical recess and is freely rotatable about its longitudinal axis, wherein the screw spindle comprises three wings which correspondingly define three screw threads, wherein the elongated cylindrical recess defines a measuring chamber, which has at least a length to enclose one and a half turns of the screw threads, and wherein the ratio of the outer diameter to the core diameter of the screw spindle is at least 1.5:1.