A medicated module attachable to a drug delivery device, wherein the drug delivery device comprises a primary reservoir of a first medicament and a distal end with first attachment means, wherein the medicated module comprises a second medicament, the medicated module having a proximal end and a distal end and further comprising: a. second attachment means at the proximal end for attachment to the first attachment means of the drug delivery device, b. a second reservoir containing the second medicament; c. a cavity containing the second reservoir and a proximal needle cannula configured to provide fluid communication with the primary reservoir when the medicated module is connected thereto and a distal injection needle cannula, the second reservoir being arranged in the axial direction between the proximal and the distal needle cannula (5, 3), and the proximal and distal needle cannulae (5, 3) being configured to allow fluid communication with the second reservoir, d. a needle guard to provide protection against the distal injection needle cannula arranged in a portion of the medicated module and configured to move in an axial direction during application to an injection site; e. a guard lock comprising a rotating sleeve operably connected to the needle guard for at least temporarily disabling axial movement of the needle guard; and f. a release mechanism comprising a button accessible to a user operably connected to the guard lock for unlocking the guard lock by movement of the button such that axial movement of the needle guard is enabled, wherein the activation of the release mechanism unlocks the guard lock to allow one or more additional retractions of the needle guard after a first application of the first medicament to the injection site. a. second attachment means at the proximal end for attachment to the first attachment means of the drug delivery device, b. a second reservoir containing the second medicament; c. a cavity containing the second reservoir and a proximal needle cannula configured to provide fluid communication with the primary reservoir when the medicated module is connected thereto and a distal injection needle cannula, the second reservoir being arranged in the axial direction between the proximal and the distal needle cannula (5, 3), and the proximal and distal needle cannulae (5, 3) being configured to allow fluid communication with the second reservoir, d. a needle guard to provide protection against the distal injection needle cannula arranged in a portion of the medicated module and configured to move in an axial direction during application to an injection site; e. a guard lock comprising a rotating sleeve operably connected to the needle guard for at least temporarily disabling axial movement of the needle guard; and f. a release mechanism comprising a button accessible to a user operably connected to the guard lock for unlocking the guard lock by movement of the button such that axial movement of the needle guard is enabled, wherein the activation of the release mechanism unlocks the guard lock to allow one or more additional retractions of the needle guard after a first application of the first medicament to the injection site.