A vehicle pillar structure comprising: a transparent portion that configures a skeleton of a pillar of a vehicle, the transparent portion being made of transparent material, preferably of transparent resin, and being disposed such that a lengthwise direction thereof extends in a vehicle vertical direction; and a glass holding portion (32, 34) that is disposed at least at a vehicle width direction outer side of the transparent portion, and that holds a glass (14, 18), wherein the glass holding portion (32, 34) comprises a first glass holding portion that is disposed at a vehicle width direction inner side of the transparent portion and holds one vehicle width direction end portion of a first glass disposed at a cabin front portion or a cabin rear portion; and a second glass holding portion that is disposed at the vehicle width direction outer side of the transparent portion and holds one vehicle front-rear direction end portion of a second glass disposed at a cabin side portion, characterized in that a width dimension (D2, D3), along a direction intersecting the lengthwise direction of the transparent portion in the direction perpendicular to the viewing direction from the driver's seat, of at least one of the first glass holding portion or the second glass holding portion is set equal to or less than 65mm, and a width dimension of the transparent portion, along a direction intersecting the lengthwise direction of the transparent portion in the direction perpendicular to the viewing direction from the driver's seat, is set equal to or greater than 60mm throughout the lengthwise direction of the transparent portion. a transparent portion that configures a skeleton of a pillar of a vehicle, the transparent portion being made of transparent material, preferably of transparent resin, and being disposed such that a lengthwise direction thereof extends in a vehicle vertical direction; and a glass holding portion (32, 34) that is disposed at least at a vehicle width direction outer side of the transparent portion, and that holds a glass (14, 18), wherein the glass holding portion (32, 34) comprises a first glass holding portion that is disposed at a vehicle width direction inner side of the transparent portion and holds one vehicle width direction end portion of a first glass disposed at a cabin front portion or a cabin rear portion; and a second glass holding portion that is disposed at the vehicle width direction outer side of the transparent portion and holds one vehicle front-rear direction end portion of a second glass disposed at a cabin side portion, characterized in that a width dimension (D2, D3), along a direction intersecting the lengthwise direction of the transparent portion in the direction perpendicular to the viewing direction from the driver's seat, of at least one of the first glass holding portion or the second glass holding portion is set equal to or less than 65mm, and a width dimension of the transparent portion, along a direction intersecting the lengthwise direction of the transparent portion in the direction perpendicular to the viewing direction from the driver's seat, is set equal to or greater than 60mm throughout the lengthwise direction of the transparent portion.