A composition comprising two or more sets of different detection molecules, wherein each of the two or more sets of detection molecules comprises a nucleic acid label which is unique to and specific for the binding molecule of each of said two or more different sets of detection molecules; each set comprising a detection molecule comprising a. at least one binding molecule, wherein said binding molecule is selected from the group consisting of an antibody, an antibody mimetic, an MHC complex, CD1, MR1, a protein, a peptide, a peptide aptamer, and a ligand; b. a multimerization domain associated with the at least one binding molecule and the at least one nucleic acid label, optionally via one or more connector molecules, wherein the multimerization domain is selected from the group consisting of a peptide, a protein, a coiled-coil polypeptide structure, streptactin, a polysaccharide such as dextran, and an avidin such as a streptavidin; and c. at least one nucleic acid label, wherein said nucleic acid label comprises a 5' first primer region (forward), a barcode region and a 3' second primer region (reverse), wherein said label further comprises a random nucleotide region between the 5' first primer region and the 3' second primer region, wherein said random nucleotide region comprises 7 to 20 nucleotides, wherein said barcode region serves as an identification tag for said at least one binding molecule, and wherein said random nucleotide region is unique for each label, and wherein the primer regions of said nucleic acid label are identical for each set of detection molecules. wherein each of the two or more sets of detection molecules comprises a nucleic acid label which is unique to and specific for the binding molecule of each of said two or more different sets of detection molecules; each set comprising a detection molecule comprising a. at least one binding molecule, wherein said binding molecule is selected from the group consisting of an antibody, an antibody mimetic, an MHC complex, CD1, MR1, a protein, a peptide, a peptide aptamer, and a ligand; b. a multimerization domain associated with the at least one binding molecule and the at least one nucleic acid label, optionally via one or more connector molecules, wherein the multimerization domain is selected from the group consisting of a peptide, a protein, a coiled-coil polypeptide structure, streptactin, a polysaccharide such as dextran, and an avidin such as a streptavidin; and c. at least one nucleic acid label, wherein said nucleic acid label comprises a 5' first primer region (forward), a barcode region and a 3' second primer region (reverse), wherein said label further comprises a random nucleotide region between the 5' first primer region and the 3' second primer region, wherein said random nucleotide region comprises 7 to 20 nucleotides, a. at least one binding molecule, wherein said binding molecule is selected from the group consisting of an antibody, an antibody mimetic, an MHC complex, CD1, MR1, a protein, a peptide, a peptide aptamer, and a ligand; b. a multimerization domain associated with the at least one binding molecule and the at least one nucleic acid label, optionally via one or more connector molecules, wherein the multimerization domain is selected from the group consisting of a peptide, a protein, a coiled-coil polypeptide structure, streptactin, a polysaccharide such as dextran, and an avidin such as a streptavidin; and c. at least one nucleic acid label, wherein said nucleic acid label comprises a 5' first primer region (forward), a barcode region and a 3' second primer region (reverse), wherein said label further comprises a random nucleotide region between the 5' first primer region and the 3' second primer region, wherein said random nucleotide region comprises 7 to 20 nucleotides, wherein said barcode region serves as an identification tag for said at least one binding molecule, and wherein said random nucleotide region is unique for each label, and wherein the primer regions of said nucleic acid label are identical for each set of detection molecules.