mhurhangee/ep-ind-claims huggingface dataset:
A computer processor for processing instruction packets comprising a plurality of instructions comprising at least one data processing instruction, the processor comprising: a decode unit for decoding the instruction packets fetched from a memory holding a sequence of the instruction packets; a control processing channel capable of performing control operations; and a data processing channel comprising a plurality of functional units (108, 109, 110); wherein, in use the decode unit causes a plurality of instructions comprising at least one data processing instruction to be executed simultaneously on the data processing channel; and the computer processor characterised by: the control processing channel comprising a plurality of functional units (106, 107, 108) including a control register file having a first bit width; the data processing channel capable of performing data processing operations at least one input of which is a vector; the plurality of functional units of the data processing channel including a data register file having a second bit width, wider than the first bit width; the decode unit configured to decode instruction packets sequentially and to determine from at least one identification bit of each instruction packet a type of instruction packet being decoded from a type (i) comprising a plurality of only control instructions and a type (ii) of a plurality of instructions including at least one data processing instruction, and configured to pass the plurality of only control instructions from an instruction packet of type (i) sequentially to the control processing channel and configured to pass the plurality of instructions from an instruction packet of type (ii) simultaneously to the data processing channel. a decode unit for decoding the instruction packets fetched from a memory holding a sequence of the instruction packets; a control processing channel capable of performing control operations; and a data processing channel comprising a plurality of functional units (108, 109, 110); the control processing channel comprising a plurality of functional units (106, 107, 108) including a control register file having a first bit width; the data processing channel capable of performing data processing operations at least one input of which is a vector; the plurality of functional units of the data processing channel including a data register file having a second bit width, wider than the first bit width; the decode unit configured to decode instruction packets sequentially and to determine from at least one identification bit of each instruction packet a type of instruction packet being decoded from a type (i) comprising a plurality of only control instructions and a type (ii) of a plurality of instructions including at least one data processing instruction, and configured to pass the plurality of only control instructions from an instruction packet of type (i) sequentially to the control processing channel and configured to pass the plurality of instructions from an instruction packet of type (ii) simultaneously to the data processing channel.
A pneumatic expulsion device for expelling objects or fluid substances from a reservoir by means of a drive piston which is subjectable to a gas volume compressible in a compression chamber, the drive piston being provided with a drive mechanism for compressing the gas volume and with a trigger for expanding the compressed gas volume, the compression chamber being provided with a filling mechanism for filling the vented compression chamber with compressed air, and the filling mechanism having a connection mechanism which is connected to the compression chamber and which serves to be connected to a compressed air cylinder, characterized in that the compression chamber is provided with a relief mechanism for temporarily venting and emptying the compression chamber, the connection mechanism having a pressure reducer.
Saddle tree for a saddle, especially Western saddle, with a fork, a cantle and with two rigid bars, which are joined to one another via fork and cantle and each of which has not only at least one positive curvature (7, 33) but also a twist an the underside along its centerline in longitudinal direction, characterized in that the bars are each positively curved along their centerline in longitudinal direction from the front bar end to the rear attachment of fork, then are curvature-free or negatively curved up to the front attachment of cantle and then are positively curved up to the rear bar end.
A short detection circuit for detecting a short circuit condition of an LED, comprising: a voltage threshold setting arrangement (R2, R5) for setting a voltage threshold (Vth), below which the short can be determined to have arisen, a voltage detecting circuit (R3, R4) for detecting a voltage (Vop) dependent on a LED operating voltage; and a comparison circuit for detecting the short circuit condition based on a comparison of the voltage threshold (Vth) and the detected voltage (Vop), wherein the voltage threshold setting arrangement (R2, R5) sets the voltage threshold (Vth) which is dependent on a LED operating current of the LED, such that there are at least two different voltage thresholds at two different LED operating currents, and wherein for each LED operating current the voltage threshold (Vth) corresponds to a voltage between a corresponding LED short circuit voltage, which is a voltage behavior of a shorted LED as a function of the LED operating current, and the corresponding LED operating voltage, characterized in that the voltage threshold setting arrangement comprises a resistor divider (R2, R5) supplied by a fixed voltage, and a current source which injects a current which is dependent on the LED operating current to the resistor divider (R2, R5). a voltage threshold setting arrangement (R2, R5) for setting a voltage threshold (Vth), below which the short can be determined to have arisen, a voltage detecting circuit (R3, R4) for detecting a voltage (Vop) dependent on a LED operating voltage; and a comparison circuit for detecting the short circuit condition based on a comparison of the voltage threshold (Vth) and the detected voltage (Vop), wherein the voltage threshold setting arrangement (R2, R5) sets the voltage threshold (Vth) which is dependent on a LED operating current of the LED, such that there are at least two different voltage thresholds at two different LED operating currents, and wherein for each LED operating current the voltage threshold (Vth) corresponds to a voltage between a corresponding LED short circuit voltage, which is a voltage behavior of a shorted LED as a function of the LED operating current, and the corresponding LED operating voltage, characterized in that the voltage threshold setting arrangement comprises a resistor divider (R2, R5) supplied by a fixed voltage, and a current source which injects a current which is dependent on the LED operating current to the resistor divider (R2, R5).
A compound of formula I wherein R 1 is, pyrazinyl or pyrimidyl, each of which is optionally substituted with one or more C 1-6 alkyl, halogen, hydroxy, C 1-4 fluoroalkyl, C 3-6 cycloalkyl, C 1-6 alkoxy, C 1-6 fluoroalkoxy, cyano or - SO 2 R 7; wherein R 2a and R 2b combine with the nitrogen to which they are attached to form piperazinyl, piperidinyl, morpholinyl, pyrrolidinyl, pyrrolo, imidazo, azetidinyl, 6 to 10 membered spiro(heterocyclyl), homomorpholinyl, homopiperidinyl or homopiperazinyl each of which is optionally substituted with one or more C 1-6 alkyl, C 1-6 alkenyl, C 3-6 -cycloalkyl, C 1-6 alkoxy, oxo, - NR 5 R 6 or fluorines; wherein R 3 is halogen, C 1-4 fluoroalkyl, cyano, cyclopropyl, C 1-4 alkyloxy, C 1-4 fluoroalkyloxy, - SO 2 R 7, -NR 5 R 6 or C 1-6 alkyl; wherein R 4 is halogen, C 1-6 alkyl, C 1-4 fluoroalkyl, cyano,, -NR 5 R 6, C 1-6 alkoxy, C 1-4 fluoroalkoxy or C 3-6 -cycloalkyl; wherein R 5 and R 6 independently of each other are hydrogen or C 1-6 alkyl; wherein R 7 is C 1-6 alkyl, C 3-6 cycloalkyl, C 1-4 fluoroalkyl and wherein n is 0-3; or a pharmaceutically acceptable salt thereof.
A camera, comprising: a lens holder and one or more lens elements coupled to the lens holder, wherein the one or more lens elements define an optical axis for the camera; an image sensor configured to capture light passing through the one or more lens elements and convert the captured light into image signals; and a flexure assembly comprising: a first frame coupled to the image sensor such that: the image sensor moves together with the first frame; and the first frame receives the image signals from the image sensor; a second frame coupled to a stationary component of the camera; a first layer of flexure arms configured to mechanically connect the first frame to the second frame; and a second layer of flexure arms, mounted above or below the first layer of flexure arms, configured to mechanically connect the first frame to the second frame; wherein first layer of flexure arms and the second layer of flexure arms are separated at least in part by an open space between the flexure arms. a lens holder and one or more lens elements coupled to the lens holder, wherein the one or more lens elements define an optical axis for the camera; an image sensor configured to capture light passing through the one or more lens elements and convert the captured light into image signals; and a flexure assembly comprising: a first frame coupled to the image sensor such that: the image sensor moves together with the first frame; and the first frame receives the image signals from the image sensor; a second frame coupled to a stationary component of the camera; a first layer of flexure arms configured to mechanically connect the first frame to the second frame; and a second layer of flexure arms, mounted above or below the first layer of flexure arms, configured to mechanically connect the first frame to the second frame; wherein first layer of flexure arms and the second layer of flexure arms are separated at least in part by an open space between the flexure arms. a first frame coupled to the image sensor such that: the image sensor moves together with the first frame; and the first frame receives the image signals from the image sensor; the image sensor moves together with the first frame; and the first frame receives the image signals from the image sensor; a second frame coupled to a stationary component of the camera; a first layer of flexure arms configured to mechanically connect the first frame to the second frame; and a second layer of flexure arms, mounted above or below the first layer of flexure arms, configured to mechanically connect the first frame to the second frame; wherein first layer of flexure arms and the second layer of flexure arms are separated at least in part by an open space between the flexure arms.
System for electrical generation, conversion, distribution and starting on board an aircraft, of the "bleedless" type, that is, with an electrical power architecture with no pneumatic circuits, characterised in that it comprises: - at least two first electrical distribution channels (B, Y) for high power loads specific to "bleedless" type aircrafts, the loads generating harmonic pollution, and - at least two second electrical distribution channels (G1, G2) for conventional loads comprising technical loads requiring high quality voltage, such as avionics, lighting, fuel pumps and commercial loads such as catering services and passenger entertainment systems, in which the first and second channels are separated, and are supplied with power by separate generators (SG-B, SG-Y; SG-G1, SG-G2) driven by the aircraft's engines (Eng1, Eng2) under normal flight conditions. - at least two first electrical distribution channels (B, Y) for high power loads specific to "bleedless" type aircrafts, the loads generating harmonic pollution, and - at least two second electrical distribution channels (G1, G2) for conventional loads comprising technical loads requiring high quality voltage, such as avionics, lighting, fuel pumps and commercial loads such as catering services and passenger entertainment systems,
Build-in alcove (1; 40; 50) for mounting in a wall, which build-in alcove (1; 40; 50) comprises: - a frame of a number of side walls (4; 51) arranged against each other, wherein at least one edge of each side wall (4; 51) lies in a common plane and these edges together define an access opening for the frame; - a door (6; 44; 57) arranged in the access opening and pivotally connected to the side walls (4; 51) of the frame, so that the door (6; 44; 57) can swing between a first position, in which the access opening is closed, and a second position, in which the access opening is left clear; wherein the door (6; 44; 57) comprises a panel with a first side and an opposite second side, wherein a finishing layer such as a tile layer can be arranged on the first side, and wherein at least two hinges are arranged between the second side and the side walls (4; 51) of the frame, wherein the pivot axes of the at least two hinges lie mutually in line and form a hinge line (16, 58) extending in front of and parallel to the first side of the panel, characterized in that each hinge comprises a hinge pin (7; 43; 56) and a hinge plate (14; 41; 53), wherein provided in the hinge plate (14; 41; 53) is an opening (42; 55) in which the hinge pin (7; 43; 56) is mounted, wherein the hinge pin (7; 43; 56) is arranged on the second side of the panel and wherein the hinge plate (14; 41; 53) lies parallel against a side wall (4; 51) of the frame. - a frame of a number of side walls (4; 51) arranged against each other, wherein at least one edge of each side wall (4; 51) lies in a common plane and these edges together define an access opening for the frame; - a door (6; 44; 57) arranged in the access opening and pivotally connected to the side walls (4; 51) of the frame, so that the door (6; 44; 57) can swing between a first position, in which the access opening is closed, and a second position, in which the access opening is left clear;
A pharmaceutical composition comprising suitable pharmaceutical excipients and also comprising a human in vivo clinical effective amount of a recombinant human growth hormone (rhGH) PEGylated prodrug conjugate, wherein PEG is linked to rhGH via a self hydrolysable (autocleavage) transient linker; said prodrug conjugate is characterized in that:: the conjugate has a GH activity which is less than 5% of the native growth hormone without PEG; and: the linker autohydrolysis rate is such that the in vivo half-life is from 10 hours to 600 hours which is measured by intravenously injecting into rats the conjugate, followed by taking blood samples at time intervals, preparing plasma and analyzing hGH using ELISA; and wherein the PEGylated prodrug conjugate has the chemical structure: wherein HN-rhGH represents the rhGH residue attached to the transient linker; R1, R2, R3, R4, and R5 are selected independently from hydrogen, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tertiary butyl; PEG represents the pegylation residue attached to the transient linker; n = 1 or 2; and X is selected from C1 to C8 alkyl or C1 to C12 heteroalkyl; and wherein the PEG is branched and contains at least 3 chains.: the conjugate has a GH activity which is less than 5% of the native growth hormone without PEG; and: the linker autohydrolysis rate is such that the in vivo half-life is from 10 hours to 600 hours which is measured by intravenously injecting into rats the conjugate, followed by taking blood samples at time intervals, preparing plasma and analyzing hGH using ELISA; and HN-rhGH represents the rhGH residue attached to the transient linker; R1, R2, R3, R4, and R5 are selected independently from hydrogen, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tertiary butyl; PEG represents the pegylation residue attached to the transient linker; n = 1 or 2; and X is selected from C1 to C8 alkyl or C1 to C12 heteroalkyl; and wherein the PEG is branched and contains at least 3 chains.
A thermoelectric sensor for measuring thermoelectric voltages with an irradiation side and an assembly side, comprising a plurality of thermoelements with measurement transitions which are formed in each case by the transitions of a first metal layer and a second metal layer merging into another metal layer, wherein the two metal layers (1, 2) sandwich an electrically insulating matrix layer, characterised in that from the assembly side a plurality of first and second blind holes (4, 4') are arranged so as to completely cross the second metal layer and the matrix layer in the transverse direction, extending in the direction of the first metal layer, wherein the internal walls of the first blind holes are covered by a third metal layer and successively a fourth metal layer and the internal walls of the second blind holes are covered by the fourth metal layer, whereby the thermoelectric sensor is configured with a body which is closed toward the irradiation side.
A magnetic load sensor comprising: a magnetic target configured to generate a magnetic field; a magnetic sensor element configured to detect a magnitude of the magnetic field generated by the magnetic target; a pair of parallel plates (2 and 3) spaced apart from each other in an axial direction and extending parallel to each other; and at least one coupling piece through which the parallel plates (2 and 3) are coupled together, wherein the coupling piece is inclined relative to the axial direction such that when a load in the axial direction is applied to the parallel plates (2 and 3), the coupling piece is deflected in such a manner that the parallel plates (2 and 3) are displaced relative to each other in a direction perpendicular to the axial direction, characterized in that the magnetic target and the magnetic sensor element are mounted to one and the other of the parallel plates (2 and 3), respectively, such that when the parallel plates (2 and 3) are displaced relative to each other in said direction perpendicular to the axial direction, the magnetic target and the magnetic sensor element are displaced relative to each other in said direction perpendicular to the axial direction. a magnetic target configured to generate a magnetic field; a magnetic sensor element configured to detect a magnitude of the magnetic field generated by the magnetic target; a pair of parallel plates (2 and 3) spaced apart from each other in an axial direction and extending parallel to each other; and at least one coupling piece through which the parallel plates (2 and 3) are coupled together, wherein the coupling piece is inclined relative to the axial direction such that when a load in the axial direction is applied to the parallel plates (2 and 3), the coupling piece is deflected in such a manner that the parallel plates (2 and 3) are displaced relative to each other in a direction perpendicular to the axial direction, characterized in that the magnetic target and the magnetic sensor element are mounted to one and the other of the parallel plates (2 and 3), respectively, such that when the parallel plates (2 and 3) are displaced relative to each other in said direction perpendicular to the axial direction, the magnetic target and the magnetic sensor element are displaced relative to each other in said direction perpendicular to the axial direction.
A power conversion system to be used with an energy source, comprising: a plurality of conversion units, each comprising a pair of input terminals and a pair of output terminals, wherein the input terminals are connected in series with the energy source, wherein the positive input terminal of a first conversion unit and the negative input terminal of a last conversion unit of the series are for connection to an output (14, 16) of the energy source, and for each two neighboring conversion units in this series a negative input terminal pin of an upstream conversion unit is connected to a positive input terminal of a downstream conversion unit; a master monitor unit (30a, 30b) adapted to monitor the output power of the energy source; and a controller adapted to control the input voltage of each conversion unit synchronously in dependence on the monitored output power, characterized in that both input terminals of each of conversion unit are decoupled from the energy source except for the positive input terminal of the first conversion unit and the negative input terminal of the last conversion unit. a plurality of conversion units, each comprising a pair of input terminals and a pair of output terminals, wherein the input terminals are connected in series with the energy source, wherein the positive input terminal of a first conversion unit and the negative input terminal of a last conversion unit of the series are for connection to an output (14, 16) of the energy source, and for each two neighboring conversion units in this series a negative input terminal pin of an upstream conversion unit is connected to a positive input terminal of a downstream conversion unit; a master monitor unit (30a, 30b) adapted to monitor the output power of the energy source; and a controller adapted to control the input voltage of each conversion unit synchronously in dependence on the monitored output power, characterized in that both input terminals of each of conversion unit are decoupled from the energy source except for the positive input terminal of the first conversion unit and the negative input terminal of the last conversion unit.
An oligonucleotide comprising the sequence 5'-GGAACAGTTCGTCCATGGC-3' (SEQ ID NO:2) for use in the treatment of an inflammatory bowel disease in a human subject via topical administration to the colon, wherein the subject has not been subjected to colonic cleaning prior to said administration.
A device configured to be insertable through an access manhole opening of a tank designed to contain fuels or other hazardous liquids, the device being configured to carry out maintenance operations, the device comprising a carriage (32, 51) of self-propelled type driven by at least one pneumatic or hydraulic motor, connected by suitable wiring (33, 53) to a remote control panel (34, 52) suitable to be located outside the tank, wherein an articulated arm (31, 50) is rotatably connected by one end thereof to the carriage (32,51), said arm comprising a tower (35, 57) hinged on the carriage (32, 51), said tower having a telescopic device which, through pneumatic pistons or pneumatic or hydraulic motors (38, 62), is able to raise up to two times the height of said tower (35, 57), wherein the articulated arm (31, 50) further comprises a gear unit (39, 63) having at least one gear axis of rotation (40, 41) located at the distal end of said telescopic device, as well as at least an articulated telescopic rod (42, 43, 65) equipped with a telescopic device (45, 46, 66) and located on said gear unit (39, 63) in such a way as to be driven by the latter, wherein at least one tool (47, 67) is applied in an interchangeable fashion at the top free end of the at least one articulated telescopic rod (42, 43, 65), wherein the at least one articulated telescopic rod (42, 43, 65) is configured to be rotated on the axis (40, 41) of the gears of the gear unit (39, 63) by means of a pneumatic or hydraulic piston (44, 64) and wherein the device further comprises a feeler device fixed close to said at least one tool on the end point of the articulated arm (31, 50) and connected to the control panel, the feeler device being configured to automatically adjust the length of the telescopic device of the articulated telescopic rod (42, 43, 65) to control the working distance of said at least one tool from the inside wall of the tank during use of the device.