A method of selective observation of non-hydrogenative para- hydrogen induced polarisation (NH-PHIP) in a material, as enhanced magnetic resonance signals, said method comprising the steps of: a) preparing a fluid containing spatially symmetric molecules comprising two halves each, with a non-Boltzmann nuclear spin state distribution of the symmetric molecules at the temperature of the fluid; b) providing a compound with a defined chemical identity; c) providing a template which binds or supports an interaction with parahydrogen and the compound and that offers sites of ordered environment for the two halves of the symmetric molecule and the compound which can be arranged at each site, wherein the ordered environment distinguishes chemically or magnetically the two halves of the symmetric molecule arranged at each site, and wherein the ordered environment allows interaction via scalar coupling or dipolar coupling between the two halves of the symmetric molecule and the compound arranged at each site; said template being selected from the group consisting of [Ir 2 (Py) 3] +, in which NHC is a saturated or unsaturated N-heterocyclic carbene; and analogues thereof; d) bringing together, at said temperature, the prepared fluid, the compound and the assembled template, thereby transferring the spin order from the symmetric molecules to the hyperpolarisable nuclei of the compound during a temporary association of the symmetric molecules, the compound at the template while ultimately keeping the chemical identity of the compound; e) performing an MR measurement on the compound comprising hyperpolarized nuclei prepared in step d); and f) separating thermal and longitudinal spin order states by suppressing or filtering a thermal magnetisation background signal created due to the interaction with a magnetic field of an instrument that is used, by the use of appropriate pulse sequences made up of appropriately phased RF pulses and receiver phases. a) preparing a fluid containing spatially symmetric molecules comprising two halves each, with a non-Boltzmann nuclear spin state distribution of the symmetric molecules at the temperature of the fluid; b) providing a compound with a defined chemical identity; c) providing a template which binds or supports an interaction with parahydrogen and the compound and that offers sites of ordered environment for the two halves of the symmetric molecule and the compound which can be arranged at each site, wherein the ordered environment distinguishes chemically or magnetically the two halves of the symmetric molecule arranged at each site, and wherein the ordered environment allows interaction via scalar coupling or dipolar coupling between the two halves of the symmetric molecule and the compound arranged at each site; said template being selected from the group consisting of [Ir 2 (Py) 3] +, in which NHC is a saturated or unsaturated N-heterocyclic carbene; and analogues thereof; d) bringing together, at said temperature, the prepared fluid, the compound and the assembled template, thereby transferring the spin order from the symmetric molecules to the hyperpolarisable nuclei of the compound during a temporary association of the symmetric molecules, the compound at the template while ultimately keeping the chemical identity of the compound; e) performing an MR measurement on the compound comprising hyperpolarized nuclei prepared in step d); and f) separating thermal and longitudinal spin order states by suppressing or filtering a thermal magnetisation background signal created due to the interaction with a magnetic field of an instrument that is used, by the use of appropriate pulse sequences made up of appropriately phased RF pulses and receiver phases.