A fluid delivery device comprising: a housing having a base including a bottom surface and a cartridge receiver configured to receive a cartridge, the cartridge having a fluid reservoir and a septum configured to be generally perpendicular to the bottom surface when the cartridge is engaged with the cartridge receiver; a needle assembly having a needle, the needle having a delivery end, a fluid coupling end, and a central portion located between the delivery end and the fluid coupling end, the fluid coupling end being fluidly disengaged from the fluid reservoir in an initial position, the fluid coupling end being fluidly coupled with the fluid reservoir in a primed position, the needle assembly being configured to translate laterally relative to the base from the initial position to the primed position, the needle assembly further comprising one or more snap features, and a channel for receiving the cartridge, wherein the cartridge receiver has a locked position in which the needle assembly is retained in the initial position and an unlocked position in which the needle assembly is able to translate from the initial position to the primed position, and wherein the cartridge receiver is configured to be in the locked position when the cartridge receiver is not engaged with the cartridge and configured to be in the unlocked position when the cartridge receiver is engaged with the cartridge; the cartridge receiver, when in the locked position, is configured to be raised vertically from the base and block the snap elements from moving towards the channel; and the cartridge receiver is configured to be depressed out of alignment with snap features on placement of a cartridge in the channel, allowing the needle assembly to be pushed toward the cartridge. a housing having a base including a bottom surface and a cartridge receiver configured to receive a cartridge, the cartridge having a fluid reservoir and a septum configured to be generally perpendicular to the bottom surface when the cartridge is engaged with the cartridge receiver; a needle assembly having a needle, the needle having a delivery end, a fluid coupling end, and a central portion located between the delivery end and the fluid coupling end, the fluid coupling end being fluidly disengaged from the fluid reservoir in an initial position, the fluid coupling end being fluidly coupled with the fluid reservoir in a primed position, the needle assembly being configured to translate laterally relative to the base from the initial position to the primed position, the needle assembly further comprising one or more snap features, and a channel for receiving the cartridge, wherein the cartridge receiver has a locked position in which the needle assembly is retained in the initial position and an unlocked position in which the needle assembly is able to translate from the initial position to the primed position, and wherein the cartridge receiver is configured to be in the locked position when the cartridge receiver is not engaged with the cartridge and configured to be in the unlocked position when the cartridge receiver is engaged with the cartridge; the cartridge receiver, when in the locked position, is configured to be raised vertically from the base and block the snap elements from moving towards the channel; and the cartridge receiver is configured to be depressed out of alignment with snap features on placement of a cartridge in the channel, allowing the needle assembly to be pushed toward the cartridge.