mhurhangee/ep-ind-claims huggingface dataset:
An implant for securing to tissue comprising: a body comprising a first metallic material and having a plurality of apertures; a fastener disposable within at least one of the plurality of apertures and securable to the tissue; and a fastener blank disposed within at least one aperture; characterized inthat the blank being configured to fill the aperture in which it is disposed without protruding from the body and wherein the fastener blank comprises a second metallic material that has a nobility that is different than the first material. a body comprising a first metallic material and having a plurality of apertures; a fastener disposable within at least one of the plurality of apertures and securable to the tissue; and a fastener blank disposed within at least one aperture; characterized inthat the blank being configured to fill the aperture in which it is disposed without protruding from the body and wherein the fastener blank comprises a second metallic material that has a nobility that is different than the first material.
An apparatus for caching data in a network, the apparatus comprising: a proxy cache configured to receive a request for an object from a client (105 - 105(n)) and to fetch data blocks (188a - 189c) from a server (110 - 110(m)) if the data blocks are not cached in the proxy cache; wherein the proxy cache is configured to consolidate mount points to a plurality of volumes (505, 510, 515, 520, 525, 530, 550m, 555m, 560m) on a plurality of servers, such that after the proxy cache receives a file handle of the object from one of the plurality of servers, the proxy cache mutates the file handle by using a hash function and the mutated file handle is sent to the client, such that the unmutated file handle may not be visible to the client; wherein if the data blocks are not cached in the proxy cache, then the proxy cache determines which particular server stores the data blocks by performing a hash computation based on the hash function; wherein the proxy cache fetches the data blocks from the particular server; wherein the proxy cache is configured to cache the data blocks within the object and as an active data set which is a data set that is presently cached in the proxy cache. a proxy cache configured to receive a request for an object from a client (105 - 105(n)) and to fetch data blocks (188a - 189c) from a server (110 - 110(m)) if the data blocks are not cached in the proxy cache; wherein the proxy cache is configured to consolidate mount points to a plurality of volumes (505, 510, 515, 520, 525, 530, 550m, 555m, 560m) on a plurality of servers, such that after the proxy cache receives a file handle of the object from one of the plurality of servers, the proxy cache mutates the file handle by using a hash function and the mutated file handle is sent to the client, such that the unmutated file handle may not be visible to the client; wherein if the data blocks are not cached in the proxy cache, then the proxy cache determines which particular server stores the data blocks by performing a hash computation based on the hash function; wherein the proxy cache fetches the data blocks from the particular server; wherein the proxy cache is configured to cache the data blocks within the object and as an active data set which is a data set that is presently cached in the proxy cache.
An organic electroluminescent element comprising a light-transmitting electrode layer that is provided on a light-transmitting substrate; an electrode layer that forms a pair with the light-transmitting electrode layer; an organic layer that is held between the electrode layers and contains an organic electroluminescent substance; a light-blocking auxiliary electrode that is formed on the light-transmitting electrode layer so as to be in contact with a part of the light-transmitting electrode layer; and an insulating coating film that covers the auxiliary electrode, wherein the auxiliary electrode has: a low resistivity layer which is provided on the light-transmitting electrode layer to contact with a part of the light-transmitting electrode layer, the low resistivity layer being formed from a low resistivity material that has a low specific resistance in comparison to the light-transmitting electrode layer; characterized by a coating layer which is provided on the low resistivity layer, the coating layer covering top and side surfaces of the low resistivity layer that do not contact the light-transmitting electrode layer, and the coating layer being formed from a metal that has a higher melting point than the low resistivity material. a low resistivity layer which is provided on the light-transmitting electrode layer to contact with a part of the light-transmitting electrode layer, the low resistivity layer being formed from a low resistivity material that has a low specific resistance in comparison to the light-transmitting electrode layer; characterized by a coating layer which is provided on the low resistivity layer, the coating layer covering top and side surfaces of the low resistivity layer that do not contact the light-transmitting electrode layer, and the coating layer being formed from a metal that has a higher melting point than the low resistivity material.
An assembly kit for preparing of a pre-filled syringe, comprising: - a gripping means (20, 21) to be attached to a proximal end section of a cartridge, which comprises an axially displaceable bung for sealing of an interior volume of the cartridge being pre-filled with an injectable medicinal product, wherein the cartridge comprises a distal end section sealed by a septum, wherein the septum is pierceable by an injection needle or cannula of a needle assembly, - a plunger rod (26; 30) connectable with the bung of the cartridge for applying distally directed thrust to the bung, and wherein the cartridge is at least partially embedded in a protecting sleeve, wherein - a needle mount undetachably and steadfastly attachable to the distal end section of the cartridge and providing a mount for the needle assembly to be coupled to the interior volume of the cartridge in a fluid-transferring way, characterised in that the needle mount comprises a threaded socket with an outer thread to be threadedly engaged with the correspondingly threaded needle assembly configured as a needle holder and - wherein the protecting sleeve comprises a foil adhesively attached almost across the entire outer surface of the cartridge. - a gripping means (20, 21) to be attached to a proximal end section of a cartridge, which comprises an axially displaceable bung for sealing of an interior volume of the cartridge being pre-filled with an injectable medicinal product, wherein the cartridge comprises a distal end section sealed by a septum, wherein the septum is pierceable by an injection needle or cannula of a needle assembly, - a plunger rod (26; 30) connectable with the bung of the cartridge for applying distally directed thrust to the bung, and wherein the cartridge is at least partially embedded in a protecting sleeve, wherein - a needle mount undetachably and steadfastly attachable to the distal end section of the cartridge and providing a mount for the needle assembly to be coupled to the interior volume of the cartridge in a fluid-transferring way, characterised in that the needle mount comprises a threaded socket with an outer thread to be threadedly engaged with the correspondingly threaded needle assembly configured as a needle holder and - wherein the protecting sleeve comprises a foil adhesively attached almost across the entire outer surface of the cartridge.
A laser machining method, comprising: emitting a laser beam having a wavelength of 900 nm to 1100 nm for cutting a sheet metal from a nozzle to irradiate the sheet metal with the laser beam, the nozzle being attached to a tip end of a machining head and having an opening formed therein; cutting the sheet metal by relatively moving the machining head with respect to a surface of the sheet metal; and vibrating the laser beam in a parallel direction with a cutting advancing direction of the sheet metal when the sheet metal is cut, characterized in that a calculation value Va is expressed by the following expression, Va = Qx + rtop + 2 × rbottom where an amplitude amount at a time of vibrating the laser beam is Qx, a radius of a first circular region having an area occupying 86% beam energy at a center side of total beam energy in a sectional area of the laser beam on a top surface of the sheet metal is rtop, and a radius of a second circular region having an area occupying 86% beam energy at a center side of total beam energy in a sectional area of the laser beam in a bottom surface of the sheet metal is rbottom, and when a standard deviation of the calculation value Va at a time of cutting sheet metals of a plurality of plate thicknesses is Vasd, a nozzle having a diameter of an opening between a minimum value obtained by 2Va - Vasd, and a maximum value obtained by 2.5 Va + Vasd is used as the nozzle. emitting a laser beam having a wavelength of 900 nm to 1100 nm for cutting a sheet metal from a nozzle to irradiate the sheet metal with the laser beam, the nozzle being attached to a tip end of a machining head and having an opening formed therein; cutting the sheet metal by relatively moving the machining head with respect to a surface of the sheet metal; and vibrating the laser beam in a parallel direction with a cutting advancing direction of the sheet metal when the sheet metal is cut, characterized in that a calculation value Va is expressed by the following expression, Va = Qx + rtop + 2 × rbottom where an amplitude amount at a time of vibrating the laser beam is Qx, a radius of a first circular region having an area occupying 86% beam energy at a center side of total beam energy in a sectional area of the laser beam on a top surface of the sheet metal is rtop, and a radius of a second circular region having an area occupying 86% beam energy at a center side of total beam energy in a sectional area of the laser beam in a bottom surface of the sheet metal is rbottom, and when a standard deviation of the calculation value Va at a time of cutting sheet metals of a plurality of plate thicknesses is Vasd, a nozzle having a diameter of an opening between a minimum value obtained by 2Va - Vasd, and a maximum value obtained by 2.5 Va + Vasd is used as the nozzle.
A non-aqueous automotive engine oil comprising at least 65% by weight base stock wherein the base stock has one of a Group II, Group III or Group IV base oil as its major component, and an organic polymeric friction reducing additive wherein the additive has a molecular weight ranging from 1000 to 30,000 Daltons (Da) and is the reaction product of a) a hydrophobic polymeric sub unit which is a polyisobutylene polymer which has been subjected to maleinisation to form polyisobutylene succinic anhydride having a molecular weight in the range of 300 to 5000 Da: b) a hydrophilic polymeric sub unit which is a polyethylene glycol; c) at least one backbone moiety capable of linking together polymeric sub units selected from a polyol and a polycarboxylic acid; and d) a chain terminating group, wherein the chain terminating group is a C12 - C22 linear saturated, branched saturated, linear unsaturated or branched unsaturated fatty carboxylic acid. a) a hydrophobic polymeric sub unit which is a polyisobutylene polymer which has been subjected to maleinisation to form polyisobutylene succinic anhydride having a molecular weight in the range of 300 to 5000 Da: b) a hydrophilic polymeric sub unit which is a polyethylene glycol; c) at least one backbone moiety capable of linking together polymeric sub units selected from a polyol and a polycarboxylic acid; and d) a chain terminating group, wherein the chain terminating group is a C12 - C22 linear saturated, branched saturated, linear unsaturated or branched unsaturated fatty carboxylic acid.
An operator control unit comprising: a user interface configured to receive one or more commands from an operator for controlling a locomotive; a receiver configured to receive location information of the operator control unit; and a wireless communication device, the wireless communication device configured to transmit command data corresponding to the one or more commands and location data corresponding to the location information to a machine control unit on the locomotive. a user interface configured to receive one or more commands from an operator for controlling a locomotive; a receiver configured to receive location information of the operator control unit; and a wireless communication device, the wireless communication device configured to transmit command data corresponding to the one or more commands and location data corresponding to the location information to a machine control unit on the locomotive.
Supercritical CO 2 arrangement for the utilization of waste heat comprising at least a waste heat exchanger (3, 3', 3"), at least two turbines (6, 6', 6"), at least two recuperators (11, 11'), and at least a cooler unit (8, 9, 8', 9', 8", 9") in at least one fluid circuit, characterized in that a pump and compressor (10, 10', 10") in one device is comprised, switchable between a pump and compressor function by a change of the rotational frequency of a rotor of the device.
A baby bottle comprising a glass container, characterized in that it also comprises a protective coating for protection against thermal shocks that covers the outside of at least a fraction of said glass container, said glass container being made of soda-lime glass and said protective coating comprising at least a first layer of a flexible material adhering to said glass container, said flexible material being a polyurethane-based material.
A method of obtaining a three-dimensional composition comprising human inner ear sensory tissue, the method comprising the steps of: (a) culturing human induced pluripotent stem cell aggregates in a culture medium comprising FGF-2, BMP4 and a small molecule inhibitor of Transforming Growth Factor Beta (TGFβ) signaling for four days, wherein the small molecule inhibitor of TGFβ is SB431542; (b) further culturing the cultured aggregates of (a) in the presence of a Fibroblast Growth Factor and a small molecule inhibitor of BMP signaling for 4 days, wherein the small molecule inhibitor of BMP is LDN-193189; (c) contacting the further cultured aggregates of (b) to a Wnt agonist for 4 days, wherein the Wnt agonist is an inhibitor of GSK3, whereby cells within the contacted aggregates differentiate into pre-otic epithelial cells; (d) embedding the pre-otic epithelial cells in a semi-solid culture medium comprising extracellular matrix protein and a basement membrane extract; (e) culturing the embedded pre-otic epithelial cells in the presence of a Wnt agonist for 6 days, wherein the Wnt agonist is an inhibitor of GSK3; and (f) culturing the embedded, pre-otic epithelial cells of (e) for at least a further 22-42 days under conditions that promote self-assembly of embedded pre-otic epithelial cells into otic vesicles, whereby a three-dimensional composition comprising human inner ear sensory tissue is obtained. (a) culturing human induced pluripotent stem cell aggregates in a culture medium comprising FGF-2, BMP4 and a small molecule inhibitor of Transforming Growth Factor Beta (TGFβ) signaling for four days, wherein the small molecule inhibitor of TGFβ is SB431542; (b) further culturing the cultured aggregates of (a) in the presence of a Fibroblast Growth Factor and a small molecule inhibitor of BMP signaling for 4 days, wherein the small molecule inhibitor of BMP is LDN-193189; (c) contacting the further cultured aggregates of (b) to a Wnt agonist for 4 days, wherein the Wnt agonist is an inhibitor of GSK3, whereby cells within the contacted aggregates differentiate into pre-otic epithelial cells; (d) embedding the pre-otic epithelial cells in a semi-solid culture medium comprising extracellular matrix protein and a basement membrane extract; (e) culturing the embedded pre-otic epithelial cells in the presence of a Wnt agonist for 6 days, wherein the Wnt agonist is an inhibitor of GSK3; and (f) culturing the embedded, pre-otic epithelial cells of (e) for at least a further 22-42 days under conditions that promote self-assembly of embedded pre-otic epithelial cells into otic vesicles, whereby a three-dimensional composition comprising human inner ear sensory tissue is obtained.
A tabbed sealing member for bonding to a rim surrounding a container opening, the tabbed sealing member comprising: a lower member including at least a seal layer for bonding to a container rim; an upper member including one or more layers and partially bonded to the lower member and including a free portion thereof not bonded to the lower member; a hinge joint formed by the partial bond between the upper member and the lower member, the hinge joint permitting the upper member free portion to pivot away from the lower member to form a gripping tab; and a folded sheet with a first folded portion bonded to the upper member free portion, a second folded portion bonded to a portion of the lower member below the free portion, and a dead fold aligned with the hinge joint, an inner surface of the first folded portion is not bonded to a facing inner surface of the second folded portion, characterized in that the folded sheet is non-symmetrical with one of the first folded portion or the second folded portion extending to a periphery of the tabbed sealing member and the other of the first folded portion or the second folded portion has a distal end spaced from the periphery of the tabbed sealing member. a lower member including at least a seal layer for bonding to a container rim; an upper member including one or more layers and partially bonded to the lower member and including a free portion thereof not bonded to the lower member; a hinge joint formed by the partial bond between the upper member and the lower member, the hinge joint permitting the upper member free portion to pivot away from the lower member to form a gripping tab; and a folded sheet with a first folded portion bonded to the upper member free portion, a second folded portion bonded to a portion of the lower member below the free portion, and a dead fold aligned with the hinge joint, an inner surface of the first folded portion is not bonded to a facing inner surface of the second folded portion,
Method for applying a radially expandable sealing ring to the outside of a corrugated pipe, the outer surface of which pipe has annularly peripheral recesses, wherein - a rotatable crucible-shaped holder causes the sealing ring to rotate at such a rotational speed that the sealing ring is in contact with the inner surface of the holder, wherein, due to centrifugal force and expansion, the inner radius of said ring becomes greater than the maximum outer radius of the corrugated pipe in the region of the outer surface of the corrugated pipe, over which outer surface the seal is to be guided as far as one of the recesses, and wherein the rotatable holder contains a central holding mandrel for receiving the sealing ring that is at rest, and the holding mandrel has a diameter that substantially corresponds to the inner diameter of the sealing ring that is at rest, - when the holder is rotating, the sealing ring is guided from the end of the pipe, via the region having the maximum outer radius, as far as a recess in which the sealing ring is to be inserted, and then - the rotational speed of the holder is reduced until the sealing ring enters the recess due to elastic relaxation. - a rotatable crucible-shaped holder causes the sealing ring to rotate at such a rotational speed that the sealing ring is in contact with the inner surface of the holder, wherein, due to centrifugal force and expansion, the inner radius of said ring becomes greater than the maximum outer radius of the corrugated pipe in the region of the outer surface of the corrugated pipe, over which outer surface the seal is to be guided as far as one of the recesses, and wherein the rotatable holder contains a central holding mandrel for receiving the sealing ring that is at rest, and the holding mandrel has a diameter that substantially corresponds to the inner diameter of the sealing ring that is at rest, - when the holder is rotating, the sealing ring is guided from the end of the pipe, via the region having the maximum outer radius, as far as a recess in which the sealing ring is to be inserted, and then - the rotational speed of the holder is reduced until the sealing ring enters the recess due to elastic relaxation.
An imaging system, comprising; a sample stage (170, 812) comprising a surface configured to support a sample to be scanned by the imaging system; an optical stage having an objective lens (142, 346), the optical stage being positionable relative to the sample stage; focus tracking circuitry electrically coupled to the optical stage; an actuator (130, 344, 490) physically coupled to at least one of the sample stage and the optical stage to move the sample stage relative to the optical stage; a servo circuit configured to control the actuator (130, 344, 490); a first set of control parameters to control the servo circuit; a second set of control parameters to control the servo circuit; and a servo control circuit configured to: apply the first set of control parameters to the servo circuit when the imaging system is operating in a first mode of operation, apply the second set of control parameters to the servo circuit when the imaging system is operating in a second mode of operation, enable feedback from the focus tracking circuitry to the servo circuit when the imaging system is operating in a scanning mode of operation, and disable feedback from the focus tracking circuitry to the servo circuit when the imaging system is operating in focus model generation mode of operation. a sample stage (170, 812) comprising a surface configured to support a sample to be scanned by the imaging system; an optical stage having an objective lens (142, 346), the optical stage being positionable relative to the sample stage; focus tracking circuitry electrically coupled to the optical stage; an actuator (130, 344, 490) physically coupled to at least one of the sample stage and the optical stage to move the sample stage relative to the optical stage; a servo circuit configured to control the actuator (130, 344, 490); a first set of control parameters to control the servo circuit; a second set of control parameters to control the servo circuit; and a servo control circuit configured to: apply the first set of control parameters to the servo circuit when the imaging system is operating in a first mode of operation, apply the second set of control parameters to the servo circuit when the imaging system is operating in a second mode of operation, enable feedback from the focus tracking circuitry to the servo circuit when the imaging system is operating in a scanning mode of operation, and disable feedback from the focus tracking circuitry to the servo circuit when the imaging system is operating in focus model generation mode of operation. apply the first set of control parameters to the servo circuit when the imaging system is operating in a first mode of operation, apply the second set of control parameters to the servo circuit when the imaging system is operating in a second mode of operation, enable feedback from the focus tracking circuitry to the servo circuit when the imaging system is operating in a scanning mode of operation, and disable feedback from the focus tracking circuitry to the servo circuit when the imaging system is operating in focus model generation mode of operation.