A fluidic sanitation device configured to purify a fluid of a polluting agent, comprising a fluidic sanitation network, characterized in that the fluidic sanitation network is a three-dimensional network of microfluidic channels, each microfluidic channel being defined by one or more fluid-tight walls, each microfluidic channel comprising at least one zone on the inner surface of said microfluidic channel presenting an autonomous sanitizing agent and each microfluidic channel presenting at the level of such a zone a height of less than 60 μm in a direction normal to the main direction of flow of the fluid, the autonomous sanitizing agent being chosen: -- from cyclodextrin, activated carbon, calixarene, activated alumina, silica gel, graphite, clay and zeolite so that the self-contained sanitizing agent is configured to capture the pollutant, or -- one of laccase, horseradish peroxidase, lignin peroxidase, manganese peroxidase, tyrosinase, potassium permanganate, persulfate and a fungal enzyme, so that the self-contained sanitizing agent is configured to degrade the pollutant, the self-contained sanitizing agent and the sizing of said zones being configured to enable capture and/or degradation of at least 10% of the pollutant by said zones, for at least one flow rate of the fluid to be purified, the device comprising a plurality of distribution channels and a plurality of collection channels, the sanitizing fluidic network connecting the distribution channels and the collection channels and being implemented at least by a network of microfluidic channels connected in parallel, at least one wall of a microfluidic channel having a plurality of reliefs extending in at least one direction different from the main fluid flow direction, the fluidic device being configured so that, when the absolute value of the pressure difference is less than 5 bar, the hydrodynamic resistance of the distribution channel(s) and the collection channel(s) is strictly less than the hydrodynamic resistance of the fluidic sewage network. -- from cyclodextrin, activated carbon, calixarene, activated alumina, silica gel, graphite, clay and zeolite so that the self-contained sanitizing agent is configured to capture the pollutant, or -- one of laccase, horseradish peroxidase, lignin peroxidase, manganese peroxidase, tyrosinase, potassium permanganate, persulfate and a fungal enzyme, so that the self-contained sanitizing agent is configured to degrade the pollutant, the self-contained sanitizing agent and the sizing of said zones being configured to enable capture and/or degradation of at least 10% of the pollutant by said zones, for at least one flow rate of the fluid to be purified, the device comprising a plurality of distribution channels and a plurality of collection channels, the sanitizing fluidic network connecting the distribution channels and the collection channels and being implemented at least by a network of microfluidic channels connected in parallel, at least one wall of a microfluidic channel having a plurality of reliefs extending in at least one direction different from the main fluid flow direction, the fluidic device being configured so that, when the absolute value of the pressure difference is less than 5 bar, the hydrodynamic resistance of the distribution channel(s) and the collection channel(s) is strictly less than the hydrodynamic resistance of the fluidic sewage network.