A simulated moving bed chromatography system (10, 41, 41', 41") comprising: at least two chromatography columns (11a, 11b, 11c, 11d; 11a', 11b', 11c'; 11a", 11b"); at least two inlet valves (13a, 13b, 13c, 13d), wherein each inlet valve (13a, 13b, 13c, 13d) is connected to a respective inlet of one of the at least two chromatography columns (11a, 11b, 11c, 11d; 11a', 11b'; 11c', 11a", 11b"); and at least two outlet valves (15a, 15b, 15c, 15d), wherein each outlet valve (15a, 15b, 15c, 15d) is connected to a respective outlet of one of the at least two chromatography columns (11a, 11b, 11c, 11d; 11a', 11b'; 11c', 11a", 11b"); characterised in that: a single feed recirculation flow path (36, 36', 36", 39) is provided in the simulated moving bed chromatography system (10, 41', 41", 41), said simulated moving bed chromatography system (10, 41', 41", 41) comprising inflows (18, 18', 18") fluidically connected to each of said at least two inlet valves (13a, 13b, 13c, 13d) and outflows (34, 34', 34") fluidically connected to each of said at least two outlet valves (15a, 15b, 15c, 15d), said single feed recirculation flow path (36, 36', 36", 39) being fluidically connected to said inflows (18, 18', 18") via a feed recirculation flow splitter (35, 35', 35") and to said outflows (34, 34', 34") via a feed recirculation flow uniter (33, 33', 33"), and wherein the simulated moving bed chromatography system (10, 41', 41", 41) is configured to recirculate outlet flow from each chromatography column (11a, 11b, 11c, 11d; 11a', 11b', 11c'; 11a", 11b") through the single feed recirculation flow path (36, 36', 36", 39) when each of said chromatography columns (11a, 11b, 11c, 11d, 11a', 11b', 11c', 11a", 11b") serves as a primary load column in a simulated moving bed chromatography process, wherein a feed recirculation of outflow from a primary load column to the inlet of a secondary load column is combined such that the feed recirculation outflow from all columns that will be used as primary load columns in the system will pass through one and the same feed recirculation flow path (36; 36'; 36"; 39), wherein the feed recirculation flow uniter (33, 33', 33") is connected to each of the outflows (34, 34', 34") and the single feed recirculation flow path (36, 36', 36"); and the feed recirculation flow splitter (35, 35', 35") is connected to each of the inflows (18, 18', 18") and the single feed recirculation flow path (36, 36', 36"). at least two chromatography columns (11a, 11b, 11c, 11d; 11a', 11b', 11c'; 11a", 11b"); at least two inlet valves (13a, 13b, 13c, 13d), wherein each inlet valve (13a, 13b, 13c, 13d) is connected to a respective inlet of one of the at least two chromatography columns (11a, 11b, 11c, 11d; 11a', 11b'; 11c', 11a", 11b"); and at least two outlet valves (15a, 15b, 15c, 15d), wherein each outlet valve (15a, 15b, 15c, 15d) is connected to a respective outlet of one of the at least two chromatography columns (11a, 11b, 11c, 11d; 11a', 11b'; 11c', 11a", 11b"); characterised in that: a single feed recirculation flow path (36, 36', 36", 39) is provided in the simulated moving bed chromatography system (10, 41', 41", 41), said simulated moving bed chromatography system (10, 41', 41", 41) comprising inflows (18, 18', 18") fluidically connected to each of said at least two inlet valves (13a, 13b, 13c, 13d) and outflows (34, 34', 34") fluidically connected to each of said at least two outlet valves (15a, 15b, 15c, 15d), said single feed recirculation flow path (36, 36', 36", 39) being fluidically connected to said inflows (18, 18', 18") via a feed recirculation flow splitter (35, 35', 35") and to said outflows (34, 34', 34") via a feed recirculation flow uniter (33, 33', 33"), and wherein the simulated moving bed chromatography system (10, 41', 41", 41) is configured to recirculate outlet flow from each chromatography column (11a, 11b, 11c, 11d; 11a', 11b', 11c'; 11a", 11b") through the single feed recirculation flow path (36, 36', 36", 39) when each of said chromatography columns (11a, 11b, 11c, 11d, 11a', 11b', 11c', 11a", 11b") serves as a primary load column in a simulated moving bed chromatography process, wherein a feed recirculation of outflow from a primary load column to the inlet of a secondary load column is combined such that the feed recirculation outflow from all columns that will be used as primary load columns in the system will pass through one and the same feed recirculation flow path (36; 36'; 36"; 39), wherein the feed recirculation flow uniter (33, 33', 33") is connected to each of the outflows (34, 34', 34") and the single feed recirculation flow path (36, 36', 36"); and the feed recirculation flow splitter (35, 35', 35") is connected to each of the inflows (18, 18', 18") and the single feed recirculation flow path (36, 36', 36").