mhurhangee/ep-ind-claims huggingface dataset:
A method of producing a cell sheet composed of retinal pigment epithelial cells, a tight junction formed between retinal pigment epithelial cells, and a basement membrane formed on a contact face with the collagen gel, comprising the following steps seeding and culturing retinal pigment epithelial cells on a collagen gel to form a cell sheet composed of the retinal pigment epithelial cells, the tight junction formed between retinal pigment epithelial cells, and the basement membrane formed on a contact face with the collagen gel, and degrading the collagen gel with collagenase to detach the cell sheet composed of the retinal pigment epithelial cells, the tight junction formed between retinal pigment epithelial cells, and the basement membrane formed on a contact face with the collagen gel. seeding and culturing retinal pigment epithelial cells on a collagen gel to form a cell sheet composed of the retinal pigment epithelial cells, the tight junction formed between retinal pigment epithelial cells, and the basement membrane formed on a contact face with the collagen gel, and degrading the collagen gel with collagenase to detach the cell sheet composed of the retinal pigment epithelial cells, the tight junction formed between retinal pigment epithelial cells, and the basement membrane formed on a contact face with the collagen gel.
A lithium battery module (202, 400, 500, 602, 604, 606) comprising: - a plurality of lithium battery cells (100, 210); and - a system configured for passing a fluid past the plurality of lithium battery cells (100, 210) in a parallel manner, wherein the system includes a battery cell container (450, 540) comprising individual battery cell containers, wherein each of the battery cells (100, 210) is located in an individual battery cell container and characterised in that each individual battery cell container includes apertures (451, 551) spaced equidistantly around the perimeter of the battery cell such that cooling fluid flowing through the apertures (451, 551) leads to an equal amount of the cooling fluid cooling the entire perimeter of the battery cell. - a plurality of lithium battery cells (100, 210); and - a system configured for passing a fluid past the plurality of lithium battery cells (100, 210) in a parallel manner, wherein the system includes a battery cell container (450, 540) comprising individual battery cell containers, wherein each of the battery cells (100, 210) is located in an individual battery cell container and characterised in that each individual battery cell container includes apertures (451, 551) spaced equidistantly around the perimeter of the battery cell such that cooling fluid flowing through the apertures (451, 551) leads to an equal amount of the cooling fluid cooling the entire perimeter of the battery cell.
Fabric for a machine for producing a fibrous web, in particular a paper, cardboard or tissue web, comprising a substrate with an upper side, a lower side, two side edges and a useful region between the two side edges, the useful region having a multiplicity of through channels which connect the upper side to the lower side of the substrate, the substrate being a laser-drilled substrate, the through channels being made in the substrate by means of a laser, characterized in that the inner surface of at least one through channel, preferably of the majority of all through channels, further preferably of all through channels in the useful region of the substrate has an averaged surface roughness R z which is greater than 4 μm, preferably greater than 6 μm, further preferably greater than 8 μm.
A method for diagnosing a health status of a Gas Insulated Switchgear, the method comprising: a) applying a DC-high-voltage at first connection points on the Gas Insulated Switchgear to apply charges on surfaces within the Gas Insulated Switchgear; b) connecting a current measuring device at second connection points at the Gas Insulated Switchgear, wherein a path between the second connection points is as a first current return path; c) measuring a first current, flowing over the first current return path; d) determining a leakage current level, related to charges within the Gas Insulated Switchgear, and setting the leakage current level as a threshold current level; e) replacing the Gas Insulated Switchgear by another Gas Insulated Switchgear; and repeating a) to c); identifying a first contamination in the Gas Insulated Switchgear, from a relation of the threshold current level determined in step d) and the height of the current over the first current return path. a) applying a DC-high-voltage at first connection points on the Gas Insulated Switchgear to apply charges on surfaces within the Gas Insulated Switchgear; b) connecting a current measuring device at second connection points at the Gas Insulated Switchgear, wherein a path between the second connection points is as a first current return path; c) measuring a first current, flowing over the first current return path; d) determining a leakage current level, related to charges within the Gas Insulated Switchgear, and setting the leakage current level as a threshold current level; e) replacing the Gas Insulated Switchgear by another Gas Insulated Switchgear; and repeating a) to c);
A container, containing a concentrate suitable for production of at least one dialysis solution, comprising at least one connecting means, by which the container can be connected to a dialysis machine or a preparation unit for liquid concentrates, characterized in that the container has air cushions as integrated supporting elements, which develop their supporting function only when a liquid and a gas are supplied to the container through the dialysis machine or the preparation unit, and wherein the air cushion is embodied in the form of an outer bag around a concentrate-filled inner bag.
A device for supporting and positioning a patient in a medical equipment, comprising: a patient support means; and a robotic arm supporting said patient support means; a robotic wrist with at least two motorized rotational degrees of freedom, said robotic wrist being borne by said robotic arm and bearing said patient support means; characterized by: a translational release unit connected between said robotic wrist and said patient support means, said translational release unit including: an XY translation mechanism providing two translational degrees of freedom; and a translation locking mechanism cooperating with said XY translation mechanism, said translation locking mechanism being switchable between a locked state, in which it locks said two translational degrees of freedom of said XY translation mechanism in a mechanically defined position, and an unlocked state, in which said two translational degrees of freedom are unlocked. a patient support means; and a robotic arm supporting said patient support means; a robotic wrist with at least two motorized rotational degrees of freedom, said robotic wrist being borne by said robotic arm and bearing said patient support means; characterized by: a translational release unit connected between said robotic wrist and said patient support means, said translational release unit including: an XY translation mechanism providing two translational degrees of freedom; and a translation locking mechanism cooperating with said XY translation mechanism, said translation locking mechanism being switchable between a locked state, in which it locks said two translational degrees of freedom of said XY translation mechanism in a mechanically defined position, and an unlocked state, in which said two translational degrees of freedom are unlocked. a translational release unit connected between said robotic wrist and said patient support means, said translational release unit including: an XY translation mechanism providing two translational degrees of freedom; and a translation locking mechanism cooperating with said XY translation an XY translation mechanism providing two translational degrees of freedom; and a translation locking mechanism cooperating with said XY translation mechanism, said translation locking mechanism being switchable between a locked state, in which it locks said two translational degrees of freedom of said XY translation mechanism in a mechanically defined position, and an unlocked state, in which said two translational degrees of freedom are unlocked.
A shielded wire harness comprising: a wire harness; a conductive sheet wrapped around the wire harness in a parallel state to the wire harness, the conductive sheet having a long belt shape along a longitudinal direction of the wire harness; and a long protection tape spirally wound around an outer circumference of the conductive sheet wrapped around the wire harness, wherein an adhesive surface is formed on a back surface side of the protection tape, the protection tape is spirally wound around the outer circumference of the conductive sheet after wrapping the conductive sheet around the wire harness thereby fixing the conductive sheet to the wire harness. a wire harness; a conductive sheet wrapped around the wire harness in a parallel state to the wire harness, the conductive sheet having a long belt shape along a longitudinal direction of the wire harness; and a long protection tape spirally wound around an outer circumference of the conductive sheet wrapped around the wire harness, wherein an adhesive surface is formed on a back surface side of the protection tape, the protection tape is spirally wound around the outer circumference of the conductive sheet after wrapping the conductive sheet around the wire harness thereby fixing the conductive sheet to the wire harness.
A system for forming a fistula between two blood vessels comprising: a first catheter, comprising a catheter body, a leaf spring electrode (802, 2002) for ablating or vaporizing tissue and at least one alignment element, wherein the leaf spring electrode (802, 2002) is moveable between a low-profile configuration and a deployed position wherein at least a portion of the leaf spring electrode deforms away from catheter body and is separated from the catheter body by a distance, wherein the electrode naturally flexes away from the catheter body. a first catheter, comprising a catheter body, a leaf spring electrode (802, 2002) for ablating or vaporizing tissue and at least one alignment element, wherein the leaf spring electrode (802, 2002) is moveable between a low-profile configuration and a deployed position wherein at least a portion of the leaf spring electrode deforms away from catheter body and is separated from the catheter body by a distance, wherein the electrode naturally flexes away from the catheter body.
A filter cartridge with a housing that has a circumferential side wall enclosing a filter volume filled at least partially with a filter granulate that is at least partially insoluble in water, a first transverse wall provided with openings, the transverse wall closing off the filter volume in an inlet area, and a second transverse wall spaced apart from the first transverse wall and also provided with openings, the second transverse wall closing off the filter volume in an outlet area, as well as a port leading from the second transverse wall to an outflow opening, characterised in that the filter granulate is configured in such a way that it cannot escape through the openings, and in that the port is provided with at least one bridging opening connecting an outer side of the filter cartridge to the outflow opening so that the flow resistance in the circuit is not substantially increased.
A component supply device (60, 160) which is configured to be arranged adjacent to a mounter which mounts components on a board and which is configured to supply the components to the mounter comprising: a replenishment section provided with a magazine which houses a component carrying member on which multiple components are arranged on a base material; and a conveyance section which conveys the component carrying member housed in the magazine, wherein the conveyance section is equipped with side surface number one to which the replenishment section is mounted; the replenishment section is slidably mounted with respect to the side surface number one of the conveyance section; the side surface number one is positioned in direction number one with respect to the center of the conveyance section; the replenishment section is slidable in a direction number two which is perpendicular to the direction number one; and the replenishment section is slidable in the direction number two within a range in which the replenishment section is not separated from the conveyance section, characterized in that the conveyance section is equipped with side surface number two positioned on the opposite side to the direction number one with respect to the center of the conveyance section; the side surface number two is configured to be arranged adjacent to the mounter when the component supply device (60, 160) is arranged adjacent to the mounter; and the replenishment section and the conveyance section can be treated as one body when arranging the component supply device (60, 160) adjacent to the mounter.
An immunomodulatory composition for use in treating a metabolic disease, disorder or condition in an individual, wherein the metabolic disease, disorder or condition is selected from obesity, diabetes mellitus, insulin resistance, glucose metabolism disorders, hypoinsulinemia, atherosclerosis, hypercholesterolemia, hypertriglyceridemia, metabolic syndrome, hypertension, non-alcoholic fatty liver disease and glucose-intolerance; and the immunomodulatory composition comprises: a) live non-pathogenic Caulobacter crescentus; and b) a pharmaceutically acceptable excipient. a) live non-pathogenic Caulobacter crescentus; and b) a pharmaceutically acceptable excipient.
A strain wave gearing device comprising: a rigid internally toothed gear; a flexible externally toothed gear of a cup shape or a silk hat shape; a wave generator which is mounted on an inner side of the externally toothed gear, flexes the externally toothed gear in a non-circular shape to partly mesh with the internally toothed gear, and moves meshing positions of the two gears (5, 6) in a circumferential direction; and a grease temperature control mechanism for controlling a temperature of a grease portion covering an outer peripheral side portion of the wave generator, of grease filled inside the externally toothed gear; wherein the grease temperature control mechanism includes a heater facing the outer peripheral side portion of the wave generator over an entire circumference thereof from a direction of a device central axis line characterized in that the heater is in contact with an inner peripheral surface of the externally toothed gear over an entire circumference of the inner peripheral surface or the heater is attached to an inner peripheral surface of the externally toothed gear over an entire circumference of the inner peripheral surface, and the heater has a flexibility capable of flexing together with the inner peripheral surface of the externally toothed gear. a rigid internally toothed gear; a flexible externally toothed gear of a cup shape or a silk hat shape; a wave generator which is mounted on an inner side of the externally toothed gear, flexes the externally toothed gear in a non-circular shape to partly mesh with the internally toothed gear, and moves meshing positions of the two gears (5, 6) in a circumferential direction; and a grease temperature control mechanism for controlling a temperature of a grease portion covering an outer peripheral side portion of the wave generator, of grease filled inside the externally toothed gear; wherein the grease temperature control mechanism includes a heater facing the outer peripheral side portion of the wave generator over an entire circumference thereof from a direction of a device central axis line characterized in that the heater is in contact with an inner peripheral surface of the externally toothed gear over an entire circumference of the inner peripheral surface or the heater is attached to an inner peripheral surface of the externally toothed gear over an entire circumference of the inner peripheral surface, and the heater has a flexibility capable of flexing together with the inner peripheral surface of the externally toothed gear.
A method for reading film grain patterns in a raster order in film grain simulation comprising: establishing a start read offset position for selecting samples of the film grain patterns; the method being characterised by the steps of: repeating said start read offset position for each display line of a group of film grain blocks from the film grain patterns by resetting at least one seed value for each group of film grain blocks such that the seed values are the same for the beginning of each display line of the group of film grain blocks; and using a different start read offset position for each display line of a next group of film grain blocks. establishing a start read offset position for selecting samples of the film grain patterns; the method being characterised by the steps of: repeating said start read offset position for each display line of a group of film grain blocks from the film grain patterns by resetting at least one seed value for each group of film grain blocks such that the seed values are the same for the beginning of each display line of the group of film grain blocks; and using a different start read offset position for each display line of a next group of film grain blocks.
A three-dimensional modeled object comprising: a shaping material which is layered on a fabrication table (4, 141); a modeled article (10, 11a-11c, 12-15) which is formed inside the shaping material; and a support which is formed inside the shaping material and is formed with a predetermined gap (d 0 -d 20) with respect to the modeled article (10, 11a-11c, 12-15), wherein a plurality of the modeled articles (10, 11a-11c, 12-15) is formed in the height direction, and the support includes a plate-shaped support (23a, 23b) which is provided between two modeled articles (10, 11a-11c, 12-15) adjacent to each other in the height direction, characterized in that the support includes a columnar support (24a, 24b, 25a, 25b) which is higher than the modeled article (10, 11a-11c, 12-15) formed between the fabrication table and the plate-shaped support (23a, 23b) or adjacent plate-shaped supports (23a, 23b). a shaping material which is layered on a fabrication table (4, 141); a modeled article (10, 11a-11c, 12-15) which is formed inside the shaping material; and a support which is formed inside the shaping material and is formed with a predetermined gap (d 0 -d 20) with respect to the modeled article (10, 11a-11c, 12-15), wherein a plurality of the modeled articles (10, 11a-11c, 12-15) is formed in the height direction, and the support includes a plate-shaped support (23a, 23b) which is provided between two modeled articles (10, 11a-11c, 12-15) adjacent to each other in the height direction, characterized in that the support includes a columnar support (24a, 24b, 25a, 25b) which is higher than the modeled article (10, 11a-11c, 12-15) formed between the fabrication table and the plate-shaped support (23a, 23b) or adjacent plate-shaped supports (23a, 23b).
A composition for use in the treatment of cancer, comprising one or more agents for use in a CRISPR/Cas genome editing technique targeting a TMEM135-CCDC67 fusion gene present in a cancer, wherein the one or more agents comprise (i) a vector comprising a nucleic acid encoding a Cas protein or a mutant thereof and two guide RNAs (gRNA), wherein one gRNA is complementary to a region within one gene of the TMEM135-CCDC67 fusion gene and a second gRNA is complementary to a region within a second gene of the TMEM135-CCDC67 fusion gene, and (ii) a vector comprising a donor nucleic acid, that when expressed results in cell death, and one or more targeting sequences, wherein the one or more targeting sequences are complementary to one or more sequences of the TMEM135-CCDC67 fusion gene.
Laundry drying apparatus, in particular dryer or washer-dryer, comprising: a cabinet, a laundry storing compartment arranged within the cabinet, an air channel arranged within the cabinet and adapted to guide drying air in a drying air flow from at least one air outlet of the laundry storing compartment to at least one air inlet of the laundry storing compartment, a heat exchanger arranged within the air channel and being adapted to cool the drying air, a filter system arranged within the air channel downstream the laundry storing compartment and upstream of the heat exchanger, wherein the filter system comprises a first lint filter, and a filter wet cleaning unit having a nozzle for supply liquid for washing the first filter, wherein the nozzle is arranged to direct the liquid flowing out of the nozzle towards a front surface of the first filter; characterized in that the filter system further comprises a second lint filter, wherein, when the filter system is arranged within the air channel, the first lint filter is arranged upstream the second lint filter, and the first filter is configured and arranged relative to the nozzle to screen or to substantially screen the second filter from contact with liquid flowing out of the nozzle, such that no or essentially no liquid supplied to the first filter can contact the front surface of the second filter. a cabinet, a laundry storing compartment arranged within the cabinet, an air channel arranged within the cabinet and adapted to guide drying air in a drying air flow from at least one air outlet of the laundry storing compartment to at least one air inlet of the laundry storing compartment, a heat exchanger arranged within the air channel and being adapted to cool the drying air, a filter system arranged within the air channel downstream the laundry storing compartment and upstream of the heat exchanger, wherein the filter system comprises a first lint filter, and a filter wet cleaning unit having a nozzle for supply liquid for washing the first filter, wherein the nozzle is arranged to direct the liquid flowing out of the nozzle towards a front surface of the first filter; characterized in that the filter system further comprises a second lint filter, wherein, when the filter system is arranged within the air channel, the first lint filter is arranged upstream the second lint filter, and the first filter is configured and arranged relative to the nozzle to screen or to substantially screen the second filter from contact with liquid flowing out of the nozzle, such that no or essentially no liquid supplied to the first filter can contact the front surface of the second filter.