mhurhangee/ep-ind-claims huggingface dataset:
A cooling system for a gas turbine engine turbine section, comprising: a high pressure turbine section including a rotor supporting a blade having a cooling passage; a disc secured relative to the rotor aft of the high pressure turbine section and forming a cavity between the rotor and the disc; a bleed air source in fluid communication with the cavity; and an impeller arranged in the cavity and configured to increase a fluid pressure within the cavity to drive bleed air from the bleed air source and thereby provide a pressurized cooling fluid to the cooling passage, wherein the bleed air source is a stage of a high pressure compressor section; characterized in that the high pressure compressor section includes an aft hub having an aft hub leak path, the aft hub leak path in fluid communication with the cavity and configured to provide aft hub fluid to the cavity; and in that the cooling system further comprises a tangential on board injector (TOBI) having a TOBI leak path, the TOBI leak path in fluid communication with the cavity and configured to provide a TOBI fluid to the cavity. a rotor supporting a blade having a cooling passage; a disc secured relative to the rotor aft of the high pressure turbine section and forming a cavity between the rotor and the disc; a bleed air source in fluid communication with the cavity; and an impeller arranged in the cavity and configured to increase a fluid pressure within the cavity to drive bleed air from the bleed air source and thereby provide a pressurized cooling fluid to the cooling passage, wherein the bleed air source is a stage of a high pressure compressor section; characterized in that the high pressure compressor section includes an aft hub having an aft hub leak path, the aft hub leak path in fluid communication with the cavity and configured to provide aft hub fluid to the cavity; and in that the cooling system further comprises a tangential on board injector (TOBI) having a TOBI leak path, the TOBI leak path in fluid communication with the cavity and configured to provide a TOBI fluid to the cavity.
A process for purification of fatty acid alkyl esters (FAAE) comprising: (a) treating fatty acid alkyl esters (FAAE) utilizing one or more adsorbent columns containing an adsorbent material for removing one or more impurities from the fatty acid alkyl esters (FAAE), wherein said fatty acid alkyl esters (FAAE) continuously flow through said one or more adsorbent columns; (b) regenerating the adsorbent material with a solvent for removing adsorbed impurities from the adsorbent material; and (c) re-using the regenerated adsorbent material in step (a), characterized in that the solvent in step (b) contains an acid. (a) treating fatty acid alkyl esters (FAAE) utilizing one or more adsorbent columns containing an adsorbent material for removing one or more impurities from the fatty acid alkyl esters (FAAE), wherein said fatty acid alkyl esters (FAAE) continuously flow through said one or more adsorbent columns; (b) regenerating the adsorbent material with a solvent for removing adsorbed impurities from the adsorbent material; and (c) re-using the regenerated adsorbent material in step (a),
An in vitro method of increasing anti-inflammatory activity of a reference glycoprotein preparation, the method comprising: providing a reference glycoprotein preparation comprising glycoproteins comprising an IgG Fc region; sialylating the branched glycans on the Fc region on the α1-3 arm of a plurality of said branched glycans to produce a sialylated glycoprotein preparation; measuring in said sialylated glycoprotein preparation the level of said branched glycans having a sialic acid on the α1-3 arm and processing said sialylated glycoprotein preparation into a pharmaceutical preparation if the level of branched glycans having a sialic acid on the α1-3 arm meets a predetermined level; wherein said sialylated glycoprotein preparation has an increased level of anti-inflammatory activity relative to the level of anti-inflammatory activity of said reference glycoprotein preparation; and wherein the step of sialylating comprises contacting the reference glycoprotein preparation with a sialyltransferase enzyme, wherein the sialyltransferase enzyme is an ST6Gal enzyme prepared by expressing the enzyme in CHO cells and purifying the enzyme. providing a reference glycoprotein preparation comprising glycoproteins comprising an IgG Fc region; sialylating the branched glycans on the Fc region on the α1-3 arm of a plurality of said branched glycans to produce a sialylated glycoprotein preparation; measuring in said sialylated glycoprotein preparation the level of said branched glycans having a sialic acid on the α1-3 arm and processing said sialylated glycoprotein preparation into a pharmaceutical preparation if the level of branched glycans having a sialic acid on the α1-3 arm meets a predetermined level; wherein said sialylated glycoprotein preparation has an increased level of anti-inflammatory activity relative to the level of anti-inflammatory activity of said reference glycoprotein preparation; and wherein the step of sialylating comprises contacting the reference glycoprotein preparation with a sialyltransferase enzyme, wherein the sialyltransferase enzyme is an ST6Gal enzyme prepared by expressing the enzyme in CHO cells and purifying the enzyme.
A system for a wind turbine comprising: - a pitch system comprising a pitch bearing and a wind turbine hub, the pitch bearing being attached to the hub and being attachable to a wind turbine rotor blade; and - a pitch gear releaseably coupled to the pitch system; and - a flange for coupling the pitch gear to the pitch system; the flange, in use, being connected to the pitch bearing or hub and being arranged to support the pitch gear between the axis of rotation of the pitch bearing and the pitch bearing circumference and at a position between the pitch bearing and the blade tip. - a pitch system comprising a pitch bearing and a wind turbine hub, the pitch bearing being attached to the hub and being attachable to a wind turbine rotor blade; and - a pitch gear releaseably coupled to the pitch system; and - a flange for coupling the pitch gear to the pitch system;
A bifunctional aptamer conjugate comprising: (i) the sequence 5' -GCG CGG TAC CGC GCT AAC GGA GGT TGC GTC CGT- 3' (SEQ ID NO:3); or (ii) the sequence of SEQ ID NO:3 having one, two, three, four or five substitutions therein, wherein the aptamer conjugate binds to EpCAM and TfR. (i) the sequence 5' -GCG CGG TAC CGC GCT AAC GGA GGT TGC GTC CGT- 3' (SEQ ID NO:3); or (ii) the sequence of SEQ ID NO:3 having one, two, three, four or five substitutions therein, wherein the aptamer conjugate binds to EpCAM and TfR.
A method for obtaining a cellular composition comprising epithelial stem cells (EpSCs) from mammalian skin, whereby said EpSCs are derived from the epidermal layer, comprising the steps of: - at least partially separating the epidermal layer from the dermal layer; of a skin sample - obtaining a cell suspension from said epidermal layer by performing at least one enzymatic dissociation step; and - culturing said cell suspension under low-attachment conditions. - at least partially separating the epidermal layer from the dermal layer; of a skin sample - obtaining a cell suspension from said epidermal layer by performing at least one enzymatic dissociation step; and - culturing said cell suspension under low-attachment conditions.
A controller for a motor vehicle comprising: means for receiving information indicative of a current vehicle speed; means for receiving information indicative of an amount of brake force a braking system of the vehicle is developing or is capable of developing; means for receiving information indicative of a gradient of a driving surface on which the vehicle is driving; and torque transmission reduction means for causing a powertrain torque reduction operation to be performed in which the controller causes one or more components in a torque transmission path from a torque delivery device to one or more driven wheels of the vehicle to assume a torque reduction condition in which torque transmission from the torque delivery device to the one or more driven wheels is reduced or substantially terminated; the controller being configured automatically to cause the torque reduction operation to be performed in dependence at least in part on the information indicative of current vehicle speed, information indicative of brake force amount and information indicative of driving surface gradient the controller being further configured to determine, in dependence on the brake force information and gradient information, whether the amount of brake force would be sufficient to hold the vehicle stationary should the vehicle come to a halt on the current driving surface, the controller being configured to not to allow the torque reduction operation to take place if the amount of brake force would not be sufficient to hold the vehicle stationary on the current driving surface. means for receiving information indicative of a current vehicle speed; means for receiving information indicative of an amount of brake force a braking system of the vehicle is developing or is capable of developing; means for receiving information indicative of a gradient of a driving surface on which the vehicle is driving; and torque transmission reduction means for causing a powertrain torque reduction operation to be performed in which the controller causes one or more components in a torque transmission path from a torque delivery device to one or more driven wheels of the vehicle to assume a torque reduction condition in which torque transmission from the torque delivery device to the one or more driven wheels is reduced or substantially terminated; the controller being configured automatically to cause the torque reduction operation to be performed in dependence at least in part on the information indicative of current vehicle speed, information indicative of brake force amount and information indicative of driving surface gradient the controller being further configured to determine, in dependence on the brake force information and gradient information, whether the amount of brake force would be sufficient to hold the vehicle stationary should the vehicle come to a halt on the current driving surface, the controller being configured to not to allow the torque reduction operation to take place if the amount of brake force would not be sufficient to hold the vehicle stationary on the current driving surface.
1-{5-cyclopropyl-2-[(propan-2-yl)oxy]pyridin-3-yl}- N- (2-methylquinoline-5-sulfonyl)cyclopropane-1-carboxamide, or a pharmaceutically acceptable salt thereof.
An ignition system for a lawn care device, the ignition system comprising: a processor; a device interface configured to interface between the processor and a data bus operably coupled to a plurality of switches associated with respective components of the lawn care device, wherein the processor is configured to monitor status of the plurality of switches associated with respective components of the lawn care device, characterized in that the processor is further configured to monitor opposing switching statuses of at least one of the switches by detecting each of the opposing switching statuses, respectively, wherein the processor is configured to compare the opposing switching statuses to determine a fault status of the at least one of the switches and wherein the processor is configured to count each instance of activation of the opposing switching statuses and compare the count to determine the fault status. a processor; a device interface configured to interface between the processor and a data bus operably coupled to a plurality of switches associated with respective components of the lawn care device, wherein the processor is configured to monitor status of the plurality of switches associated with respective components of the lawn care device, characterized in that the processor is further configured to monitor opposing switching statuses of at least one of the switches by detecting each of the opposing switching statuses, respectively, wherein the processor is configured to compare the opposing switching statuses to determine a fault status of the at least one of the switches and wherein the processor is configured to count each instance of activation of the opposing switching statuses and compare the count to determine the fault status.
Vehicle, in particular rail vehicle for high-speed traffic, with - a wagon body and - an air duct (107.2) for directing a first air flow in the wagon body, - the air duct (107.2) having an outlet opening (107.4), which opens into an environment of the wagon body in an outlet area (107.5) on a surface (102.1) of the wagon body over which a second air stream flows during operation of the vehicle, characterized in that - the outlet opening (107.4) is arranged in the region of an essentially convex transition of the surface (102.1) into an indentation of the surface (102.1). - a wagon body and - an air duct (107.2) for directing a first air flow in the wagon body, - the air duct (107.2) having an outlet opening (107.4), which opens into an environment of the wagon body in an outlet area (107.5) on a surface (102.1) of the wagon body over which a second air stream flows during operation of the vehicle, characterized in that - the outlet opening (107.4) is arranged in the region of an essentially convex transition of the surface (102.1) into an indentation of the surface (102.1).
A fill level valve for a pressure equalization line of a fluid tank assembly, wherein the pressure equalization line is fluidically connected between a fluid tank and a filling line opening into the fluid tank, wherein the fill level valve comprises a connecting piece which can be arranged on the fluid tank, from which a dip tube, which can be arranged in the fluid tank, and which is fluidically connected to the connecting piece, originates from the connecting piece, wherein a flow resistance formed by a constricted through-flow cross section is provided in the dip tube, characterized in that the fill level valve is designed in such a way that upon fluid reaching the dip tube, due to a pressure equalization only possible in the dip tube, upon further filling of fluid into the fluid tank, a fluid level rises faster in the dip tube than outside the dip tube and the fluid reaches the flow resistance, before a floater interacts with a valve seat to interrupt the fluidic connection through the fill level valve, so that the pressure loss via the fill level valve increases, upon the fluid reaching the flow resistance, to suppress or restrict the venting of the fluid tank through the fill level valve.
A method of assembling into sets gas turbine engine components characterized in that: there is a plurality of gas turbine engine components each have flow passages; and in that the method comprises: classifying the flow capability through the flow passages of each one of the plurality of the gas turbine engine components; and assembling into sets gas turbine engine components having the same flow capability classification. there is a plurality of gas turbine engine components each have flow passages; and in that the method comprises: classifying the flow capability through the flow passages of each one of the plurality of the gas turbine engine components; and assembling into sets gas turbine engine components having the same flow capability classification.
Rotatable laundry drum, having a drum casing and a drum rear wall, wherein - the drum rear wall has at least one perforated air passage region (15, 15a), and - at least one unperforated shaped area, which faces in the direction of a drum inner area, is introduced into the perforated air passage region, - wherein the at least one shaped area has at least one fin extending radially outwards, characterised in that - the fin extends such that it is curved in the direction of rotation of the laundry drum. - the drum rear wall has at least one perforated air passage region (15, 15a), and - at least one unperforated shaped area, which faces in the direction of a drum inner area, is introduced into the perforated air passage region, - wherein the at least one shaped area has at least one fin extending radially outwards, characterised in that - the fin extends such that it is curved in the direction of rotation of the laundry drum.
A sealing arrangement for a control device for the flow of coolant in a cooling circuit of a vehicle, comprising a sealing frame, a support element and a spring arranged between the sealing frame and the support element, wherein the sealing frame has an annular sealing surface which can be pressed by the spring against a movable control element of the control device, characterised in that the sealing frame has, on the side opposite its sealing surface, at least two spring supports with an intermediate space arranged between them, the support element has, on its side facing the sealing frame, at least one spring support which enters into the at least one intermediate space of the sealing frame when the sealing frame and the support element move towards each other, and the spring is a spring washer which is in contact both with the spring supports of the sealing frame and with said at least one spring support of the support element. the sealing frame has an annular sealing surface which can be pressed by the spring against a movable control element of the control device, characterised in that the sealing frame has, on the side opposite its sealing surface, at least two spring supports with an intermediate space arranged between them, the support element has, on its side facing the sealing frame, at least one spring support which enters into the at least one intermediate space of the sealing frame when the sealing frame and the support element move towards each other, and the spring is a spring washer which is in contact both with the spring supports of the sealing frame and with said at least one spring support of the support element.
A wheel loader comprising: a vehicle frame an engine mounted on the vehicle frame; an operating fluid tank disposed in front of the engine; a front support frame fixed to the vehicle frame; a rear support frame disposed facing the front support frame with the engine interposed therebetween and fixed to the vehicle frame; a base member disposed above the engine and having one end fixed to an upper part of the front support frame and the other end fixed to an upper part of the rear support frame; and a diesel particulate filtering device, a nitrogen oxide reduction catalyst device and a connecting pipe, all mounted on the base member, and the connecting pipe connecting the diesel particulate filtering device and the nitrogen oxide reduction catalyst device, characterised in that the front support frame supports the operating fluid tank. a vehicle frame an engine mounted on the vehicle frame; an operating fluid tank disposed in front of the engine; a front support frame fixed to the vehicle frame; a rear support frame disposed facing the front support frame with the engine interposed therebetween and fixed to the vehicle frame; a base member disposed above the engine and having one end fixed to an upper part of the front support frame and the other end fixed to an upper part of the rear support frame; and a diesel particulate filtering device, a nitrogen oxide reduction catalyst device and a connecting pipe, all mounted on the base member, and the connecting pipe connecting the diesel particulate filtering device and the nitrogen oxide reduction catalyst device, characterised in that the front support frame supports the operating fluid tank.
Support fitting for supporting a shelf on a side of a piece of furniture, comprising: - a main body destined to be housed in a seat obtained in an edge of the shelf, the body comprising a pass-through cavity to contain a transverse screw, with an axis, to be fixed to the side, and - a movable member capable of being pressed against the walls of the seat to anchor the main body thereto. - a main body destined to be housed in a seat obtained in an edge of the shelf, the body comprising a pass-through cavity to contain a transverse screw, with an axis, to be fixed to the side, and - a movable member capable of being pressed against the walls of the seat to anchor the main body thereto.
A data migration method, comprising: performing (301; 601), by a source base station, a transmission control protocol, TCP, proxy for user equipment; learning (301; 602), by the source base station, that the user equipment is to be handed over to a target base station; sending (304, 308; 603), by the source base station, context information to the target base station, wherein the context information comprises a sequence number of a data packet, and the sequence number of the data packet is a largest sequence number of data packets that have been acknowledged by the user equipment or a smallest sequence number of data packets that have not been acknowledged by the user equipment, the data packets separately including a plurality of byte stream-based sequentially numbered data segments with each data segment corresponding to one sequence number, wherein the largest sequence number is the sequence number of a last data segment of a data packet received and acknowledged by the user equipment to the source base station, and wherein the smallest sequence number is the sequence number of a first data segment of a data packet not acknowledged by the user equipment to the source base station; and migrating (305, 309; 604), by the source base station by using the stream control transmission protocol, SCTP, the data packets that have not been acknowledged by the user equipment to the target base station, so that the target base station receives, based on the sequence number of the data packet, the data packets that have not been acknowledged by the user equipment. performing (301; 601), by a source base station, a transmission control protocol, TCP, proxy for user equipment; learning (301; 602), by the source base station, that the user equipment is to be handed over to a target base station; sending (304, 308; 603), by the source base station, context information to the target base station, wherein the context information comprises a sequence number of a data packet, and the sequence number of the data packet is a largest sequence number of data packets that have been acknowledged by the user equipment or a smallest sequence number of data packets that have not been acknowledged by the user equipment, the data packets separately including a plurality of byte stream-based sequentially numbered data segments with each data segment corresponding to one sequence number, wherein the largest sequence number is the sequence number of a last data segment of a data packet received and acknowledged by the user equipment to the source base station, and wherein the smallest sequence number is the sequence number of a first data segment of a data packet not acknowledged by the user equipment to the source base station; and migrating (305, 309; 604), by the source base station by using the stream control transmission protocol, SCTP, the data packets that have not been acknowledged by the user equipment to the target base station, so that the target base station receives, based on the sequence number of the data packet, the data packets that have not been acknowledged by the user equipment.