A single-use compression lancing device comprising: a lower housing extending from a first end to a second end, the first end comprising an opening defining a cavity therein, the cavity comprising an internal surface, the internal surface having at least one interengagement feature (32,34) formed therein; an upper housing extending from a first end to a second end, the first end comprising a lancet opening and the second end comprising a second opening defining a cavity therein, the lancet opening and the second opening being in communication with the cavity, wherein at least a portion of the cavity defines an internal surface having an angled wall near the lancet opening; and a lancet configured for selective interengagement and guidance within the lower and upper housings, comprising a main body portion extending from a first end to a second end, the first end comprising a needle extending therefrom, the upper housing being configured for slidingly engaging the bottom housing such that manipulation of the upper housing relative to the lower housing causes a sharp tip of the needle to protrude from the lancet opening, characterized in that: at least a portion of the main body of the lancet comprises at least one resiliently flexible arm extending therefrom for sliding interengagement with the angled wall of the upper housing; the lower housing further comprises a first locking feature (42,44,46), and the second end of the lancet main body portion comprises a second locking feature (122,124) for interengagement with the first locking feature; and the at least one resiliently flexible arm extending from the lancet interengages with the angled wall of the upper housing such that the lancet is retracted within a portion of the lower housing. a lower housing extending from a first end to a second end, the first end comprising an opening defining a cavity therein, the cavity comprising an internal surface, the internal surface having at least one interengagement feature (32,34) formed therein; an upper housing extending from a first end to a second end, the first end comprising a lancet opening and the second end comprising a second opening defining a cavity therein, the lancet opening and the second opening being in communication with the cavity, wherein at least a portion of the cavity defines an internal surface having an angled wall near the lancet opening; and a lancet configured for selective interengagement and guidance within the lower and upper housings, comprising a main body portion extending from a first end to a second end, the first end comprising a needle extending therefrom, the upper housing being configured for slidingly engaging the bottom housing such that manipulation of the upper housing relative to the lower housing causes a sharp tip of the needle to protrude from the lancet opening, characterized in that: at least a portion of the main body of the lancet comprises at least one resiliently flexible arm extending therefrom for sliding interengagement with the angled wall of the upper housing; the lower housing further comprises a first locking feature (42,44,46), and the second end of the lancet main body portion comprises a second locking feature (122,124) for interengagement with the first locking feature; and the at least one resiliently flexible arm extending from the lancet interengages with the angled wall of the upper housing such that the lancet is retracted within a portion of the lower housing. at least a portion of the main body of the lancet comprises at least one resiliently flexible arm extending therefrom for sliding interengagement with the angled wall of the upper housing; the lower housing further comprises a first locking feature (42,44,46), and the second end of the lancet main body portion comprises a second locking feature (122,124) for interengagement with the first locking feature; and the at least one resiliently flexible arm extending from the lancet interengages with the angled wall of the upper housing such that the lancet is retracted within a portion of the lower housing.