mhurhangee/ep-ind-claims huggingface dataset:
A method for screening a compound candidate for use in the treatment of a neurodegenerative disorder comprising the steps consisting of: a) providing a plurality of neurons expressing BASIGIN on their surface; b) incubating said neurons with a candidate compound; c1) determining whether said candidate compound binds to BASIGIN and c2) - determining neuron viability; an increased viability of neuron in a culture medium comprising the candidate compound compared to a control without candidate compound being indicative of an activation of BASIGIN; and/or - analyzing the downstream molecular signalling pathway by measuring the intracellular ATP content; an increased intracellular ATP content compared to a control without candidate compound being indicative of an activation of BASIGIN; thereby determining whether said candidate compound activates BASIGIN and d) selecting candidate compounds that bind to and activate BASIGIN; wherein the neurons are selected from the group consisting of cone photoreceptor neurons, retina cells, retinoblastoma and other immortalized neuronal cell lines of any species. a) providing a plurality of neurons expressing BASIGIN on their surface; b) incubating said neurons with a candidate compound; c1) determining whether said candidate compound binds to BASIGIN and c2) - determining neuron viability; an increased viability of neuron in a culture medium comprising the candidate compound compared to a control without candidate compound being indicative of an activation of BASIGIN; and/or - analyzing the downstream molecular signalling pathway by measuring the intracellular ATP content; an increased intracellular ATP content compared to a control without candidate compound being indicative of an activation of BASIGIN; thereby determining whether said candidate compound activates BASIGIN and - determining neuron viability; an increased viability of neuron in a culture medium comprising the candidate compound compared to a control without candidate compound being indicative of an activation of BASIGIN; - analyzing the downstream molecular signalling pathway by measuring the intracellular ATP content; an increased intracellular ATP content compared to a control without candidate compound being indicative of an activation of BASIGIN; d) selecting candidate compounds that bind to and activate BASIGIN;
A slot die coater, comprising: a lower die block and an upper die block; a shim plate interposed between the lower die block and the upper die block to form a slot therebetween; and a manifold disposed in the lower die block, the manifold being configured to accommodate a coating solution, wherein the coating solution is configured to be delivered and coated on a substrate through an exit port in communication with the slot, and wherein the shim plate includes a plate-shaped member having an open portion which is cut in at least an area to determine a coating width of a coating layer coated on the substrate, and a structure protruding from the plate-shaped member and inserted into the manifold, characterized in that the structure is a branch structure for splitting the coating solution coming out of an injection port at a bottom of the manifold into two branches. a lower die block and an upper die block; a shim plate interposed between the lower die block and the upper die block to form a slot therebetween; and a manifold disposed in the lower die block, the manifold being configured to accommodate a coating solution, wherein the coating solution is configured to be delivered and coated on a substrate through an exit port in communication with the slot, and wherein the shim plate includes a plate-shaped member having an open portion which is cut in at least an area to determine a coating width of a coating layer coated on the substrate, and a structure protruding from the plate-shaped member and inserted into the manifold, characterized in that the structure is a branch structure for splitting the coating solution coming out of an injection port at a bottom of the manifold into two branches.
A refrigeration cycle apparatus, comprising: a refrigerant circuit configured to circulate refrigerant; an indoor unit configured to accommodate at least a load-side heat exchanger of the refrigerant circuit; a controller configured to control the indoor unit; and an operation unit configured to receive a manipulation on the indoor unit, the indoor unit including: a refrigerant detection unit; and an air-sending fan, the controller being configured to cause a first operation mode and a second operation mode to be executed as operation modes of the air-sending fan, the first operation mode being an operation mode in which an operation of the air-sending fan is started based on a first manipulation performed on the operation unit and the air-sending fan is stopped based on a second manipulation performed on the operation unit, the second operation mode being an operation mode in which the operation of the air-sending fan is started when refrigerant is detected by the refrigerant detection unit, the air-sending fan is prevented from being stopped based on the second manipulation, the air-sending fan is stopped based on a third manipulation different from the second manipulation, the third manipulation being a special manipulation on the operation unit, and the operation of the air-sending fan is restarted based on a fourth manipulation different from the first manipulation. a refrigerant circuit configured to circulate refrigerant; an indoor unit configured to accommodate at least a load-side heat exchanger of the refrigerant circuit; a controller configured to control the indoor unit; and an operation unit configured to receive a manipulation on the indoor unit, the indoor unit including: a refrigerant detection unit; and an air-sending fan, a refrigerant detection unit; and an air-sending fan, the controller being configured to cause a first operation mode and a second operation mode to be executed as operation modes of the air-sending fan, the first operation mode being an operation mode in which an operation of the air-sending fan is started based on a first manipulation performed on the operation unit and the air-sending fan is stopped based on a second manipulation performed on the operation unit, the second operation mode being an operation mode in which the operation of the air-sending fan is started when refrigerant is detected by the refrigerant detection unit, the air-sending fan is prevented from being stopped based on the second manipulation, the air-sending fan is stopped based on a third manipulation different from the second manipulation, the third manipulation being a special manipulation on the operation unit, and the operation of the air-sending fan is restarted based on a fourth manipulation different from the first manipulation.
Display and/or operating element comprising a layer stack having - a TFT layer, - a liquid crystal cell arranged on the TFT layer, and - a colour filter glass which is arranged in the form of a delimitation of the liquid crystal cell on its side facing away from the TFT layer and has a colour filter, wherein the colour filter glass is arranged on an outer surface of the display and/or operating element, characterized in that the colour filter glass laterally projects beyond the TFT layer and the liquid crystal cell at least regionally, and the colour filter glass is configured in the projecting region to conceal the layer stack. - a TFT layer, - a liquid crystal cell arranged on the TFT layer, and - a colour filter glass which is arranged in the form of a delimitation of the liquid crystal cell on its side facing away from the TFT layer and has a colour filter, wherein the colour filter glass is arranged on an outer surface of the display and/or operating element,
A light emitting semiconductor element package comprising: a first substrate; a semiconductor element disposed on the first substrate; first and second electrodes (181, 182) disposed on the first substrate, and electrically connected to the semiconductor element; a housing disposed on the first substrate, disposed around the semiconductor element, and having a step in an upper region thereof; a diffusion part disposed at the step of the housing, and disposed on the semiconductor element; and further characterised by a plurality of via holes passing through the first substrate and the housing; and a plurality of connection wirings (171 to 174) disposed in the plurality of via holes. a first substrate; a semiconductor element disposed on the first substrate; first and second electrodes (181, 182) disposed on the first substrate, and electrically connected to the semiconductor element; a housing disposed on the first substrate, disposed around the semiconductor element, and having a step in an upper region thereof; a diffusion part disposed at the step of the housing, and disposed on the semiconductor element; and further characterised by a plurality of via holes passing through the first substrate and the housing; and a plurality of connection wirings (171 to 174) disposed in the plurality of via holes.
An autonomous hydraulic unit, applicable in the displacement of liquids and comprising: a liquid inlet which is integrally attached to an inlet of a compression chamber of a vibrating piston pump where a piston injects the compressed liquid through a nozzle inside a heating chamber limited perimetrically and on the left side by a plastic body which in turn integrates the compression chamber and a safety valve and it is limited on the right side by a disk welded to a heating element this last responsible for heating up the liquid in its passage towards an outlet; an electronic board configured to process and use uses the information received from a temperature sensor to control the operation of the vibrating pump and the heating element ensuring at any time the characteristics of pressure and temperature of the liquid driven out through an outlet; wherein the vibrating piston pump, the heating element and the safety valve are integrally joined by the plastic body constituting a single device with a single inlet of the liquid, a single outlet of the liquid and a single electrical connection toward the outside.
A melt-formable ethylene-vinyl alcohol copolymer composition comprising: an ethylene-vinyl alcohol copolymer; an alkali metal compound; and an iron compound; characterized in that the weight ratio of the alkali metal compound to the iron compound on a metal basis is 30 to 100,000. an ethylene-vinyl alcohol copolymer; an alkali metal compound; and an iron compound;
Method, comprising: providing an untreated whole blood sample introducing the untreated whole blood sample into a device adapted for accommodating a sample in a fluid state comprising a reaction chamber wherein the reaction chamber comprises a first surface and a second surface and further comprises a microarray disposed on the first surface or the second surface; and determining the value indicative of the presence and/or amount of nucleic acids associated with a viral infection in the whole blood sample by performing a microarray-based analysis in the device. providing an untreated whole blood sample introducing the untreated whole blood sample into a device adapted for accommodating a sample in a fluid state comprising a reaction chamber wherein the reaction chamber comprises a first surface and a second surface and further comprises a microarray disposed on the first surface or the second surface; and determining the value indicative of the presence and/or amount of nucleic acids associated with a viral infection in the whole blood sample by performing a microarray-based analysis in the device.
Device for measuring a relative rotation speed and/or a relative angular position between a first rotating element and a second rotating element mounted to rotate relative to a static part, the device including: - means for generating a magnetic field rotating at a magnetic rotation speed representing a rotation speed of the first rotating element; - a sensor mounted to rotate at the rotation speed of the first rotating element or at a rotation speed of the second rotating element and sensitive to the rotating magnetic field, the sensor being adapted to produce from the rotating magnetic field a measurement signal representing the relative rotation speed and/or the relative angular position; - processing means positioned on the static part and intended to acquire the measurement signal; - first transmission means adapted to transmit the measurement signal to the processing means from the sensor, the first transmission means comprising two rotating transformers (109, 110), the generation means comprising a rotor comprising a single winding mounted on the first rotating element, the sensor comprising a stator (120, 121) comprising two windings mounted on the second rotating element, the rotor and the stator forming a resolver, the magnetic field generated inducing out-of-phase induced electric currents in the windings of the stator, the out-of-phase induced electric currents representing the relative speed between the first rotating element and the second rotating element, the out-of-phase induced electric currents themselves inducing measurement electric currents which are acquired by the processing means via the two rotating transformers. - means for generating a magnetic field rotating at a magnetic rotation speed representing a rotation speed of the first rotating element; - a sensor mounted to rotate at the rotation speed of the first rotating element or at a rotation speed of the second rotating element and sensitive to the rotating magnetic field, the sensor being adapted to produce from the rotating magnetic field a measurement signal representing the relative rotation speed and/or the relative angular position; - processing means positioned on the static part and intended to acquire the measurement signal; - first transmission means adapted to transmit the measurement signal to the processing means from the sensor, the first transmission means comprising two rotating transformers (109, 110), the generation means comprising a rotor comprising a single winding mounted on the first rotating element, the sensor comprising a stator (120, 121) comprising two windings mounted on the second rotating element, the rotor and the stator forming a resolver,
A method of operating a relay station, RS, in a wireless communication system, the method comprising: receiving subframe configuration information through a higher layer signal from a base station, BS; and configuring a downlink subframe, to be used for receiving a signal from the BS, based on the subframe configuration information, wherein a first downlink transmission, from the BS to the RS, and a second downlink transmission, from the RS to a user equipment, UE, are performed at different times and in a downlink frequency band, wherein a first uplink transmission, from the RS to the BS, and a second uplink transmission, from the UE to the RS, are performed at different times and in an uplink frequency band, wherein the downlink subframe to be used for receiving a signal is configured per a specific number of subframes with an exception of a first downlink subframe, a fifth downlink subframe, a sixth downlink subframe and a tenth downlink subframe of a frame, and wherein the frame comprises 10 downlink subframes. receiving subframe configuration information through a higher layer signal from a base station, BS; and configuring a downlink subframe, to be used for receiving a signal from the BS, based on the subframe configuration information, wherein a first downlink transmission, from the BS to the RS, and a second downlink transmission, from the RS to a user equipment, UE, are performed at different times and in a downlink frequency band, wherein a first uplink transmission, from the RS to the BS, and a second uplink transmission, from the UE to the RS, are performed at different times and in an uplink frequency band, wherein the downlink subframe to be used for receiving a signal is configured per a specific number of subframes with an exception of a first downlink subframe, a fifth downlink subframe, a sixth downlink subframe and a tenth downlink subframe of a frame, and wherein the frame comprises 10 downlink subframes.
An article of footwear mold comprising: an inner ring mold having an inner medial sidewall molding surface and an inner lateral sidewall molding surface; an outer ring mold having an outer medial sidewall molding surface and an outer lateral sidewall molding surface, wherein the inner medial sidewall molding surface and the outer medial sidewall molding surface in combination form a medial sidewall molding surface of the article of footwear mold and the inner lateral sidewall molding surface and the outer lateral sidewall molding surface in combination form a lateral sidewall molding surface of the article of footwear mold; and a bottom plate positioned between the inner medial sidewall molding surface and the inner lateral sidewall molding surface; characterized in that the article of footwear mold further comprises a polymeric film composition securement; wherein the polymeric film composition securement comprises a vacuum port at a top surface of the inner ring mold. an inner ring mold having an inner medial sidewall molding surface and an inner lateral sidewall molding surface; an outer ring mold having an outer medial sidewall molding surface and an outer lateral sidewall molding surface, wherein the inner medial sidewall molding surface and the outer medial sidewall molding surface in combination form a medial sidewall molding surface of the article of footwear mold and the inner lateral sidewall molding surface and the outer lateral sidewall molding surface in combination form a lateral sidewall molding surface of the article of footwear mold; and a bottom plate positioned between the inner medial sidewall molding surface and the inner lateral sidewall molding surface; characterized in that the article of footwear mold further comprises a polymeric film composition securement; wherein the polymeric film composition securement comprises a vacuum port at a top surface of the inner ring mold.
A herbicidal composition effective against mature weeds, comprising: water; 8% to 30% by weight of a herbicidally active limonene component; 0.05% to 10% by weight of a polyethoxylated castor oil emulsifying agent; a wetting agent; and a pH modifier effective to provide a pH greater than 5. 8% to 30% by weight of a herbicidally active limonene component; 0.05% to 10% by weight of a polyethoxylated castor oil emulsifying agent; a wetting agent; and a pH modifier effective to provide a pH greater than 5.
Cash box having a receiving area for receiving banknotes, a voiding unit for irreversibly voiding banknotes designed in the receiving area, a sensor unit with at least one sensor for detecting manipulation attempts, and a control unit for controlling the voiding unit, wherein the control unit is designed such that, in an activated operating state of the cash box, said control unit triggers the voiding unit if the sensor unit detects a manipulation attempt and, in a deactivated operating state of the cash box, said control unit does not trigger the voiding unit in the event of a manipulation attempt, characterized in that the control unit is designed such that, before the cash box is activated, the planned function of at least one sensor of the sensor unit is checked, and in that a setpoint signal value is stored in the control unit for each sensor to be checked before activation, and in that the control unit is designed such that it calculates an actual signal value of the respective sensor in order to check the function of each sensor to be checked, and compares said calculated actual signal value with the respective setpoint signal value.
An industrial vehicle comprising: an engine; a hydraulic actuator (15, 16); a hydraulic pump driven by the engine; an instruction member (25, 26) operated to instruct operation of the hydraulic actuator (15, 16); a supply passage (22, 23, 32, 33, 34) adapted to supply hydraulic oil discharged from the hydraulic pump to the hydraulic actuator (15, 16); a return passage (24, 32, 35) adapted to return the hydraulic oil discharged from the hydraulic pump to an oil tank; and a controller adapted to compare an engine speed and a predetermined comparison threshold value, wherein the controller is adapted so that when the engine speed is less than the comparison threshold value, the controller opens the return passage (24, 32, 35) so that the hydraulic oil flows through the return passage (24, 32, 35), wherein the comparison threshold value includes a first threshold value and a second threshold value that is lower than the first threshold value, and the controller is adapted to, in response to the operation of the instruction member (25, 26), open the return passage (24, 32, 35) so that the hydraulic oil flows through the return passage (24, 32, 35), perform revving control to increase the engine speed, and change the comparison threshold value from the first threshold value to the second threshold value. an engine; a hydraulic actuator (15, 16); a hydraulic pump driven by the engine; an instruction member (25, 26) operated to instruct operation of the hydraulic actuator (15, 16); a supply passage (22, 23, 32, 33, 34) adapted to supply hydraulic oil discharged from the hydraulic pump to the hydraulic actuator (15, 16); a return passage (24, 32, 35) adapted to return the hydraulic oil discharged from the hydraulic pump to an oil tank; and a controller adapted to compare an engine speed and a predetermined comparison threshold value, wherein the controller is adapted so that when the engine speed is less than the comparison threshold value, the controller opens the return passage (24, 32, 35) so that the hydraulic oil flows through the return passage (24, 32, 35), wherein the comparison threshold value includes a first threshold value and a second threshold value that is lower than the first threshold value, and the controller is adapted to, in response to the operation of the instruction member (25, 26), open the return passage (24, 32, 35) so that the hydraulic oil flows through the return passage (24, 32, 35), perform revving control to increase the engine speed, and change the comparison threshold value from the first threshold value to the second threshold value.
Apparatus for damping torsional vibrations of a shaft, comprising a first assembly which is fixed to the shaft and a second assembly which can be rotated relative to the first assembly about a rotational axis of the shaft, at least one energy store being arranged between the first and the second assembly, which energy store stores energy during a relative rotation of the first assembly with respect to the second assembly, the energy store comprising at least one compression spring which is clamped in cut-outs (13, 14) of the first and second assembly (7, 8), and the apparatus comprising at least one damper element which dissipates energy during a relative rotation of the first assembly with respect to the second assembly, characterized in that the damper element performs dry or viscous friction work, in that the damper element comprises friction linings which are connected in each case fixedly to the first assembly and the second assembly so as to rotate with them, and can slide frictionally on one another, and in that the damper element comprises a front friction element which is connected fixedly to the first assembly, a front outer friction ring and/or a front inner friction ring which are connected fixedly to the second assembly being in frictional contact with the front friction element.