A system for maneuvering a handling device intended to equip the frame of a vehicle for loading and unloading a crate; said handling device comprising an arm consisting of a subframe, a central frame articulated on the subframe and at least one movable element linked directly or indirectly to the central frame, a movable element being provided at its free end with a hook adapted to come into engagement with a gripping member such as a ring secured to the front of the crate, said system comprising: - a set of one or several sensors among an angular sensor and/or an inclinometer and/or a linear sensor and/or a position sensor, the sensor(s) being configured to perform respectively a measurement of angle and/or inclination and/or stroke and/or position continuously during a manipulation of the arm; - a processing unit configured to determine the position (Pc) of the hook continuously during the manipulation of the arm, from one or several measurement(s) performed by the set of one or several sensors, the position (Pc) of the hook corresponding to a Cartesian position of the hook in a reference frame XOY, the reference frame XOY having as abscissa axis a horizontal axis oriented rearwardly of the vehicle and as ordinate axis an axis oriented upwards; - a non-volatile memory adapted to store characteristics of at least one area of interest (Za, Zr, Zrc, Zre, Zoc) defined in the reference frame XOY; the processing unit being further configured to check, continuously during the manipulation of the arm, whether the determined position (Pc) of the hook is inside the at least one area of interest (Za, Zr, Zrc, Zre, Zoc), characterized in that the non-volatile memory comprises the characteristics of two areas (Za, Zr) corresponding to: - a slow-down area (Zr), in which the speed of the hook is intended to be slowed down relative to a speed of the hook outside said slow-down area (Zr) during an operation of hooking the crate via the hook, the processing unit being configured to limit the speed of the hook when the position (Pc) of the hook is in the slow-down area (Zr), and - a stopping area (Za), in which the speed of the hook is intended to be zero during an operation of hooking the crate via the hook, the processing unit being configured to block the arm when the position (Pc) of the hook is in the stopping area (Za). - a set of one or several sensors among an angular sensor and/or an inclinometer and/or a linear sensor and/or a position sensor, the sensor(s) being configured to perform respectively a measurement of angle and/or inclination and/or stroke and/or position continuously during a manipulation of the arm; - a processing unit configured to determine the position (Pc) of the hook continuously during the manipulation of the arm, from one or several measurement(s) performed by the set of one or several sensors, the position (Pc) of the hook corresponding to a Cartesian position of the hook in a reference frame XOY, the reference frame XOY having as abscissa axis a horizontal axis oriented rearwardly of the vehicle and as ordinate axis an axis oriented upwards; - a non-volatile memory adapted to store characteristics of at least one area of interest (Za, Zr, Zrc, Zre, Zoc) defined in the reference frame XOY; - a slow-down area (Zr), in which the speed of the hook is intended to be slowed down relative to a speed of the hook outside said slow-down area (Zr) during an operation of hooking the crate via the hook, the processing unit being configured to limit the speed of the hook when the position (Pc) of the hook is in the slow-down area (Zr), and - a stopping area (Za), in which the speed of the hook is intended to be zero during an operation of hooking the crate via the hook, the processing unit being configured to block the arm when the position (Pc) of the hook is in the stopping area (Za).