An intrauterine device comprising: - a wire having free ends, said wire configured to be deliverable from a delivery guide; wherein when inside the delivery guide the wire is configured to remain in a linear configuration; wherein, when the wire is advanced out of the delivery guide, a portion of the wire is configured to form a three dimensional structure; wherein the three dimensional structure a) is elastically deformable to a partially collapsed configuration; b) has a crush force of at least 15 grams/cm2; and c) is configured to elastically contract and expand in response to contraction and expansion of the uterine cavity, wherein said three dimensional structure is formed by two or more contiguous loops of the wire which are angled with respect to each other, wherein the loops are 12-18 mm in diameter and are arranged such that one loop is positioned within the plane of the second loop and is angled 60-120, preferably 80-100 degrees with respect thereto, characterized in that the wire comprises a plurality of beads (22, 24, 26) attached to the wire; wherein the plurality of beads (22, 24, 26) a) are 1.5-6.0 mm in diameter b) freely slide upon the wire; and c) comprise an active agent. - a wire having free ends, said wire configured to be deliverable from a delivery guide; wherein when inside the delivery guide the wire is configured to remain in a linear configuration; wherein, when the wire is advanced out of the delivery guide, a portion of the wire is configured to form a three dimensional structure; wherein the three dimensional structure a) is elastically deformable to a partially collapsed configuration; b) has a crush force of at least 15 grams/cm2; and c) is configured to elastically contract and expand in response to contraction and expansion of the uterine cavity, wherein said three dimensional structure is formed by two or more contiguous loops of the wire which are angled with respect to each other, wherein the loops are 12-18 mm in diameter and are arranged such that one loop is positioned within the plane of the second loop and is angled 60-120, preferably 80-100 degrees with respect thereto, characterized in that the wire comprises a plurality of beads (22, 24, 26) attached to the wire; wherein the plurality of beads (22, 24, 26) a) are 1.5-6.0 mm in diameter b) freely slide upon the wire; and c) comprise an active agent. wherein when inside the delivery guide the wire is configured to remain in a linear configuration; wherein, when the wire is advanced out of the delivery guide, a portion of the wire is configured to form a three dimensional structure; wherein the three dimensional structure a) is elastically deformable to a partially collapsed configuration; b) has a crush force of at least 15 grams/cm2; and c) is configured to elastically contract and expand in response to contraction and expansion of the uterine cavity, a) is elastically deformable to a partially collapsed configuration; b) has a crush force of at least 15 grams/cm2; and c) is configured to elastically contract and expand in response to contraction and expansion of the uterine cavity, wherein said three dimensional structure is formed by two or more contiguous loops of the wire which are angled with respect to each other, wherein the loops are 12-18 mm in diameter and are arranged such that one loop is positioned within the plane of the second loop and is angled 60-120, preferably 80-100 degrees with respect thereto, characterized in that the wire comprises a plurality of beads (22, 24, 26) attached to the wire; wherein the plurality of beads (22, 24, 26) a) are 1.5-6.0 mm in diameter b) freely slide upon the wire; and c) comprise an active agent. a) are 1.5-6.0 mm in diameter b) freely slide upon the wire; and c) comprise an active agent.