A compound of Formula I: or an enantiomer or diastereomer thereof; or a pharmaceutically acceptable salt thereof; wherein ring A is phenyl or a heteroaryl ring selected from pyridyl, thiazolyl, or isoquinolinyl; wherein when ring A is thiazolyl, ring A is optionally substituted with up to 3 substituents selected from R 1, R 2, R 3 or R 4, and wherein when ring A is phenyl, pyridyl, or isoquinolinyl, ring A is optionally substituted with up to 4 substituents selected from R 1, R 2, R 3 or R 4; R 1 is H, alkoxy, halo, triazolyl, thiazolyl, pyridazinyl, pyrimidinyl, oxazolyl, isoxazolyl, oxadiazolyl, pyridyl, phenyl, or pyrazolyl, wherein triazolyl, thiazolyl, pyridazinyl, pyrimidinyl, oxazolyl, isoxazolyl, oxadiazolyl, pyridyl, phenyl or pyrazolyl is optionally substituted with up to two substituents selected from halo or alkyl; R 2 is H, alkyl, alkoxy, or halo; Z is NH, N-CH 3, N-CH 2 CH 3, N-CH 2 -cyclopropyl, N-C(=O)CH 3, N-CH 2 CH 2 OCH 3 or O; R 3 is H, alkyl, alkoxy, halo, triazolyl, thiazolyl, pyridazinyl, pyrimidinyl, pyrazinyl, oxazolyl, isoxazolyl, oxadiazolyl, pyridyl, phenyl, or pyrazolyl, wherein triazolyl, thiazolyl, pyridazinyl, pyrimidinyl, pyrazinyl, oxazolyl, isoxazolyl, oxadiazolyl, pyridyl, phenyl or pyrazolyl is optionally substituted with up to two substituents selected from halo, alkyl, NO 2, or hydroxy-alkoxy; R 4 is H or alkyl; or R 3 and R 4, together with the atoms to which they are attached, form a 6-membered aryl ring or a 5- or 6-membered heteroaryl ring; R 5 is pyridyl, pyrazinyl, benzoxazolyl, pyridazinyl, naphthyridinyl, pyrimidinyl, quinoxalinyl, quinolinyl, or phenyl, wherein the pyridyl, pyrazinyl, benzoxazolyl, pyridazinyl, naphthyridinyl pyrimidinyl, quinoxalinyl, quinolinyl, or phenyl is optionally substituted with up to two substituents selected from halo, alkoxy, hydroxymethyl or alkyl; R 6A and R 6B are independently selected from H, alkyl, hydroxyalkyl, -alkyl-alkoxy, -alkyl-alkoxy-alkoxy or -CO 2 -alkyl; and n is 1 or 2, wherein one or both of R 6A and R 6B is other than H. ring A is phenyl or a heteroaryl ring selected from pyridyl, thiazolyl, or isoquinolinyl; wherein when ring A is thiazolyl, ring A is optionally substituted with up to 3 substituents selected from R 1, R 2, R 3 or R 4, and wherein when ring A is phenyl, pyridyl, or isoquinolinyl, ring A is optionally substituted with up to 4 substituents selected from R 1, R 2, R 3 or R 4; R 1 is H, alkoxy, halo, triazolyl, thiazolyl, pyridazinyl, pyrimidinyl, oxazolyl, isoxazolyl, oxadiazolyl, pyridyl, phenyl, or pyrazolyl, wherein triazolyl, thiazolyl, pyridazinyl, pyrimidinyl, oxazolyl, isoxazolyl, oxadiazolyl, pyridyl, phenyl or pyrazolyl is optionally substituted with up to two substituents selected from halo or alkyl; R 2 is H, alkyl, alkoxy, or halo; Z is NH, N-CH 3, N-CH 2 CH 3, N-CH 2 -cyclopropyl, N-C(=O)CH 3, N-CH 2 CH 2 OCH 3 or O; R 3 is H, alkyl, alkoxy, halo, triazolyl, thiazolyl, pyridazinyl, pyrimidinyl, pyrazinyl, oxazolyl, isoxazolyl, oxadiazolyl, pyridyl, phenyl, or pyrazolyl, wherein triazolyl, thiazolyl, pyridazinyl, pyrimidinyl, pyrazinyl, oxazolyl, isoxazolyl, oxadiazolyl, pyridyl, phenyl or pyrazolyl is optionally substituted with up to two substituents selected from halo, alkyl, NO 2, or hydroxy-alkoxy; R 4 is H or alkyl; or R 3 and R 4, together with the atoms to which they are attached, form a 6-membered aryl ring or a 5- or 6-membered heteroaryl ring; R 5 is pyridyl, pyrazinyl, benzoxazolyl, pyridazinyl, naphthyridinyl, pyrimidinyl, quinoxalinyl, quinolinyl, or phenyl, wherein the pyridyl, pyrazinyl, benzoxazolyl, pyridazinyl, naphthyridinyl pyrimidinyl, quinoxalinyl, quinolinyl, or phenyl is optionally substituted with up to two substituents selected from halo, alkoxy, hydroxymethyl or alkyl; R 6A and R 6B are independently selected from H, alkyl, hydroxyalkyl, -alkyl-alkoxy, -alkyl-alkoxy-alkoxy or -CO 2 -alkyl; and or R 3 and R 4, together with the atoms to which they are attached, form a 6-membered aryl ring or a 5- or 6-membered heteroaryl ring; R 5 is pyridyl, pyrazinyl, benzoxazolyl, pyridazinyl, naphthyridinyl, pyrimidinyl, quinoxalinyl, quinolinyl, or phenyl, wherein the pyridyl, pyrazinyl, benzoxazolyl, pyridazinyl, naphthyridinyl pyrimidinyl, quinoxalinyl, quinolinyl, or phenyl is optionally substituted with up to two substituents selected from halo, alkoxy, hydroxymethyl or alkyl; R 6A and R 6B are independently selected from H, alkyl, hydroxyalkyl, -alkyl-alkoxy, -alkyl-alkoxy-alkoxy or -CO 2 -alkyl; and n is 1 or 2, wherein one or both of R 6A and R 6B is other than H.