A connector for connection with a fluid transfer device, said connector comprising: an outer body having a longitudinal axis; a luer lock connection port (100, 100') positioned within the outer body and configured to be coupled with an external port of said fluid transfer device, the luer lock connection port being rotatable about the longitudinal axis in a clockwise direction as well as a counter-clockwise direction, seen from the direction of the fluid transfer device into the connector along the longitudinal axis, at least prior to initiation of coupling thereof with the external port, wherein the outer body is structured, and the luer lock connection port is positioned therewithin, such that to prevent an operator to access, through the outer body, directly by fingertips an exterior of the luer lock connection port after the luer lock connection port has been coupled with the external port; a coupling facilitating mechanism configured to selectively assume a coupling enabled state at which it restricts the rotation of the luer lock connection port at least in the clockwise direction, and a coupling disabled state at which it allows the rotation of the luer lock connection port at least in the clockwise direction; and a decoupling facilitating mechanism configured to selectively assume a decoupling disabled state at which it allows rotation of the luer lock connection port about the longitudinal axis thereof at least in the counter-clockwise direction, and a decoupling enabled state at which it restricts the rotation of the luer lock connection port at least in the counter-clockwise direction so as to allow decoupling of the external port from the luer lock connection port wherein the luer lock connection port is configured to axially displace along the longitudinal axis between a first position associated with the coupling disabled state, and a second position associated with the coupling enabled state, and wherein the luer lock connection port is configured to axially displace along the longitudinal axis into a third position, wherein the third position is the first position, or any position between the first position and the second position, wherein the luer lock connection port is configured to freely displace from the second position to the third position upon application of a pulling force during decoupling the external port from the luer lock connection port, characterised in that the decoupling facilitating mechanism is configured to assume the decoupling enabled state only upon the luer lock connection port displacing into the third position. an outer body having a longitudinal axis; a luer lock connection port (100, 100') positioned within the outer body and configured to be coupled with an external port of said fluid transfer device, the luer lock connection port being rotatable about the longitudinal axis in a clockwise direction as well as a counter-clockwise direction, seen from the direction of the fluid transfer device into the connector along the longitudinal axis, at least prior to initiation of coupling thereof with the external port, wherein the outer body is structured, and the luer lock connection port is positioned therewithin, such that to prevent an operator to access, through the outer body, directly by fingertips an exterior of the luer lock connection port after the luer lock connection port has been coupled with the external port; a coupling facilitating mechanism configured to selectively assume a coupling enabled state at which it restricts the rotation of the luer lock connection port at least in the clockwise direction, and a coupling disabled state at which it allows the rotation of the luer lock connection port at least in the clockwise direction; and a decoupling facilitating mechanism configured to selectively assume a decoupling disabled state at which it allows rotation of the luer lock connection port about the longitudinal axis thereof at least in the counter-clockwise direction, and a decoupling enabled state at which it restricts the rotation of the luer lock connection port at least in the counter-clockwise direction so as to allow decoupling of the external port from the luer lock connection port wherein the luer lock connection port is configured to axially displace along the longitudinal axis between a first position associated with the coupling disabled state, and a second position associated with the coupling enabled state, and wherein the luer lock connection port is configured to axially displace along the longitudinal axis into a third position, wherein the third position is the first position, or any position between the first position and the second position, wherein the luer lock connection port is configured to freely displace from the second position to the third position upon application of a pulling force during decoupling the external port from the luer lock connection port, characterised in that the decoupling facilitating mechanism is configured to assume the decoupling enabled state only upon the luer lock connection port displacing into the third position.