mhurhangee/ep-ind-claims huggingface dataset:
A method for coating particles with calcium phosphate (CaP), wherein the particles are negatively charged, the method comprising: contacting the particles with a first solution containing calcium ions; removing the first solution to obtain a precipitate; and contacting the precipitate with a second solution containing phosphate ions to obtain CaP-coated particles, wherein the negatively charged particles comprise a polymer or polymer mixture, and wherein the second solution is selected from the group consisting of ammonium dihydrogenphosphate solution, disodium hydrogen phosphate, dipotassium hydrogen phosphate, and orthophosphoric acid. contacting the particles with a first solution containing calcium ions; removing the first solution to obtain a precipitate; and contacting the precipitate with a second solution containing phosphate ions to obtain CaP-coated particles, wherein the negatively charged particles comprise a polymer or polymer mixture, and wherein the second solution is selected from the group consisting of ammonium dihydrogenphosphate solution, disodium hydrogen phosphate, dipotassium hydrogen phosphate, and orthophosphoric acid.
An engineered Gram-negative bacterium for the production of a polysaccharide, wherein the Gram-negative bacterium comprises (a) a nucleic acid encoding a regulatory gene wzg, wzh, wzd or wze of S. pneumoniae capsular polysaccharide gene cluster CPS1, CPS2, CPS3, CPS4, CPS5, CPS6 (A and B), CPS7 (A,B,C), CPS8, CPS9 (A,L,N,V), CPS10 (A,B,C,F), CPS11 (A,B,C,D,F), CPS12 (A,B,F), CPS13, CPS14, CPS15 (A,B,C,F), CPS16 (A,F), CPS17 (A,F), CPS18 (A,B,C,F), CPS19 (A,B,C,F), CPS20, CPS21, CPS22 (A,F), CPS23 (A,B,F), CPS24 (A,B,F), CPS25 (A,F), CPS26, CPS27, CPS28 (A,F), CPS29, CPS31, CPS32 (A,F), CPS33 (A,B,C,D,F), CPS34, CPS35 (A,B,C,D,F), CPS36, CPS37, CPS38, CPS39, CPS40, CPS41 (A,F), CPS42, CPS43, CPS44, CPS45, CPS46, CPS47 (A,F), or CPS48; or (b) a nucleic acid encoding a regulatory gene capA, capB or capC of Staphylococcus aureus capsular polysaccharide gene cluster CPS5, or CPS8; or (c) a nucleic acid encoding a regulatory gene CpsA, CpsB, CpsC or CpsD of Streptococcus agalactiae (group B, GBS) capsular polysaccharide gene cluster CPSIa, CPSIb, CPSII, CPSIII, CPSIV, CPSV, CPSVI, CPSVII, or CPSVIII. wherein the expression and activity of UDP-glucose:undecaprenyl phosphate glucose-phosphate transferase activity is increased.
A medical device, comprising: an elongate body defining a distal portion, a proximal portion and a fluid flow path through at least a portion of the proximal portion, at least one electrode disposed on the distal portion of the elongate body; a temperature sensor proximate the electrode; at least one of the electrodes and temperature sensor being isolated from the fluid flow path; a heat transfer element disposed within the elongate body defining a first portion in thermal communication with the electrode and a second portion in thermal communication with a fluid flow path; characterised by: the distal portion and the proximal portion being separated by a fluidically-sealing element disposed within the elongate body; and at least a portion of the heat transfer element passing through the fluidically-sealing element. an elongate body defining a distal portion, a proximal portion and a fluid flow path through at least a portion of the proximal portion, at least one electrode disposed on the distal portion of the elongate body; a temperature sensor proximate the electrode; at least one of the electrodes and temperature sensor being isolated from the fluid flow path; a heat transfer element disposed within the elongate body defining a first portion in thermal communication with the electrode and a second portion in thermal communication with a fluid flow path; characterised by: the distal portion and the proximal portion being separated by a fluidically-sealing element disposed within the elongate body; and the distal portion and the proximal portion being separated by a fluidically-sealing element disposed within the elongate body; and at least a portion of the heat transfer element passing through the fluidically-sealing element.
A method for preparing a high activity ethylene polymerization catalyst, wherein said method comprising the following steps: (a) adding magnesium halide into an alcohol solvent selected from ethanol, isopropanol, butanol, hexanol, 2-hexanol, octanol, or a mixture thereof; (b) precipitating the solution obtained from (a) in a solution of organic solvent containing an organo compound of group III element selected from an alkyl compound of group III element, tris(halophenyl)borane, alkylaluminium alkoxide, dialkylaluminium chloride, or a mixture thereof; (c) adding a titanium compound selected from trialkoxy titanium monochloride, dialkoxy titanium dichloride, alkoxy titanium trichloride, titanium halide, or a mixture thereof into the mixture obtained from (b) to obtain a catalyst; (d) treating the catalyst obtained from (c) with an organoaluminium compound selected from trialkylaluminium, alkylaluminium alkoxide, alkylaluminium halide, or a mixture thereof at a temperature ranging from 0 to 60 °C for 2 to 5 hours, wherein the mole ratio of aluminium to titanium (Al/Ti) for treatment is in a range of 1 to 30. (a) adding magnesium halide into an alcohol solvent selected from ethanol, isopropanol, butanol, hexanol, 2-hexanol, octanol, or a mixture thereof; (b) precipitating the solution obtained from (a) in a solution of organic solvent containing an organo compound of group III element selected from an alkyl compound of group III element, tris(halophenyl)borane, alkylaluminium alkoxide, dialkylaluminium chloride, or a mixture thereof; (c) adding a titanium compound selected from trialkoxy titanium monochloride, dialkoxy titanium dichloride, alkoxy titanium trichloride, titanium halide, or a mixture thereof into the mixture obtained from (b) to obtain a catalyst; (d) treating the catalyst obtained from (c) with an organoaluminium compound selected from trialkylaluminium, alkylaluminium alkoxide, alkylaluminium halide, or a mixture thereof at a temperature ranging from 0 to 60 °C for 2 to 5 hours, wherein the mole ratio of aluminium to titanium (Al/Ti) for treatment is in a range of 1 to 30.
Data transmission system having a data transmission channel (2; 2 1, 2 2) and a plurality of transmission and reception units, wherein the data transmission channel (2; 2 1, 2 2) is an electrical line, which has a rail (4; 4 1, 4 2) made of an electrically insulating material and has at least one electrical conductor, wherein the at least one electrical conductor in each case runs in a longitudinal direction along a longitudinal axis of the rail (4; 4 1, 4 2), wherein the lateral surface of the rail (4; 4 1, 4 2) is surrounded by one of the electrical conductors and/or at least two of the electrical conductors are in each case kept apart from one other by the rail (4; 4 1, 4 2), wherein the plurality of transmission and reception units are arranged along the rail (4; 4 1, 4 2) and wherein the plurality of transmission and reception units are each configured to couple an electromagnetic wave into the electrical line or out of the electrical line, wherein a coupling device for electromagnetic near-field coupling between the transmission and reception unit and the electrical line is arranged between the transmission and reception unit and the electrical line, and wherein the coupling device has at least two coupling elements with in each case an electrical terminal and/or has at least one coupling element with in each case two electrical terminals, characterized in that the transmission and reception unit has a unit for MIMO equalization and a unit for MIMO control which are in each case connected to the electrical terminals of the coupling elements.
Refrigerator and/or freezer comprising at least one body and comprising at least one cooled interior, which is surrounded by the body, and comprising at least one closure element, by means of which the cooled interior can be closed, wherein at least one space is located between the cooled interior and the outer wall of the appliance, in which at least one vacuum insulation body is arranged which comprises a covering which defines a vacuum region, characterised in that a Peltier element and thermally conductive bodies that are in contact therewith on either side are arranged inside the vacuum region of the vacuum insulation body, wherein the Peltier element is designed to generate a temperature difference between two opposing regions on the outside of the covering, and the thermally conductive bodies are in thermally conductive contact with the Peltier element and the covering.
A thermoplastic molding composition comprising A) from 10 to 98% by weight of a thermoplastic polyamide, B) from 0.1 to 60% by weight of red phosphorus, C) from 0.5 to 20% by weight of a melamine compound, D) from 1 to 30% by weight of titanium dioxide in the rutile form, E) from 0 to 40% by weight of an impact modifier, and F) from 0 to 60% by weight of further additives, where the sum of the percentages by weight of components A) to F) is 100%. A) from 10 to 98% by weight of a thermoplastic polyamide, B) from 0.1 to 60% by weight of red phosphorus, C) from 0.5 to 20% by weight of a melamine compound, D) from 1 to 30% by weight of titanium dioxide in the rutile form, E) from 0 to 40% by weight of an impact modifier, and F) from 0 to 60% by weight of further additives,
Medical microelectrode for insertion into soft tissue, comprising an electrically conducting elongate electrode body (2, 3, 4) comprising insulated sections and having a first, proximal end and a second, distal end, the electrode body (2, 3, 4) comprising a tip section extending from its distal end, a main body section extending in a proximal direction from the tip section, and, optionally, a coupling section extending in a proximal direction from the main body section, wherein the tip section, the main body section and, optionally, the coupling section are embedded in a first electrode matrix element, disposed rotationally symmetrical in respect of the electrode sharing its longitudinal axis with that of the electrode body (2, 3, 4), which is substantially rigid, biocompatible and soluble or biodegradable in a body fluid, further comprising one or both of: a dissolution retarding layer on the first electrode matrix element; a second electrode matrix element disposed between the first electrode matrix element and the electrode; wherein a drug capable of being released upon dissolution or biodegradation of the first electrode matrix element is comprised by the first electrode matrix element or the second electrode matrix element. a dissolution retarding layer on the first electrode matrix element; a second electrode matrix element disposed between the first electrode matrix element and the electrode; wherein a drug capable of being released upon dissolution or biodegradation of the first electrode matrix element is comprised by the first electrode matrix element or the second electrode matrix element.
A method of differentiating pluripotent cells into hematopoietic precursor cells comprising the sequential steps of: a) culturing or maintaining a plurality of substantially undifferentiated pluripotent cells in a first defined media comprising at least one growth factor; b) incubating the cells for a period of from 12 hours to 7 days in a second defined media which is free or essentially free of BMP4, VEGF, IL-3, Flt3 ligand, and GMCSF, wherein said media comprises FGF-2 and/or TGF-β; c) culturing the cells in a third defined media comprising an amount of BMP4 and VEGF sufficient to promote differentiation in a plurality of the cells; and d) culturing the cells in a fourth defined media comprising an amount of IL-3 and Flt3 ligand sufficient to expand and promote differentiation in a plurality of the cells; wherein a plurality of the pluripotent cells are differentiated into hematopoietic precursor cells. a) culturing or maintaining a plurality of substantially undifferentiated pluripotent cells in a first defined media comprising at least one growth factor; b) incubating the cells for a period of from 12 hours to 7 days in a second defined media which is free or essentially free of BMP4, VEGF, IL-3, Flt3 ligand, and GMCSF, wherein said media comprises FGF-2 and/or TGF-β; c) culturing the cells in a third defined media comprising an amount of BMP4 and VEGF sufficient to promote differentiation in a plurality of the cells; and d) culturing the cells in a fourth defined media comprising an amount of IL-3 and Flt3 ligand sufficient to expand and promote differentiation in a plurality of the cells;
A magnesium alloy suitable for use as a corrodible downhole article, wherein the alloy comprises: (a) 11-15wt% Y, (b) 0.5-5wt% in total of rare earth metals other than Y, (c) 0-1wt% Zr, (d) 0.1-5wt% Ni, (e) 0-1wt% Gd, and (f) 0-1wt% Ce, wherein the remainder of the alloy is magnesium and incidental impurities. (a) 11-15wt% Y, (b) 0.5-5wt% in total of rare earth metals other than Y, (c) 0-1wt% Zr, (d) 0.1-5wt% Ni, (e) 0-1wt% Gd, and (f) 0-1wt% Ce, wherein the remainder of the alloy is magnesium and incidental impurities.
An installation for melting a composition of raw materials, suitable for obtaining glass wool, textile glass yarns and/or flat glass, which comprises a melting chamber equipped with at least one submerged burner, characterized in that the melting chamber, preferentially cylindrical in shape, is defined by side walls made of refractory material in accordance with the ISO/R836 orAFNOR NF B 40-001 standards and a bare metal bottom to which said burner is attached and which is traversed by a network of pipes adapted for the circulation of a cooling fluid, preferentially water.
A method comprising: generating a dereverberated audio signal based on an original audio signal containing reverberation by; using sinusoidal modeling to separate the original audio signal into a sinusoidal component and a noisy residual component, applying a dereverberation algorithm to the noisy residual component to generate a dereverberated noisy residual component, summing the sinusoidal component to the dereverberated noisy residual component thereby to generate the dereverberated audio signal; and generating audio analysis data based on audio analysis of the original audio signal and audio analysis of the dereverberated audio signal, wherein the method is characterised by performing beat period determination analysis on the dereverberated audio signal and performing beat time determination analysis on the original audio signal. generating a dereverberated audio signal based on an original audio signal containing reverberation by; using sinusoidal modeling to separate the original audio signal into a sinusoidal component and a noisy residual component, applying a dereverberation algorithm to the noisy residual component to generate a dereverberated noisy residual component, summing the sinusoidal component to the dereverberated noisy residual component thereby to generate the dereverberated audio signal; and generating audio analysis data based on audio analysis of the original audio signal and audio analysis of the dereverberated audio signal, wherein the method is characterised by performing beat period determination analysis on the dereverberated audio signal and performing beat time determination analysis on the original audio signal.
A self-propelled forage harvester having a central, elevated walkway extending in a longitudinal direction along the harvester above machine parts situated below on a floor of the harvester, characterized in that said harvester has at least two opposing exterior side panels, each of said side panels movable between a closed position in which each panel extends in a substantially vertical plane between the walkway and the floor of the harvester providing protection to a side of the harvester, and an open position, wherein when in the open position each panel is in a raised position that extends in a substantially vertical plane providing access underneath the panel to the machine parts and wherein at least a portion of each panel projects above the walkway providing a safety barrier along two edges of the walkway.
A method of shaping a laminated glass structure (10; 142) comprising a flexible glass sheet (14; 146) having a thickness of no greater than 0.3 mm laminated to a non-glass substrate (18; 148) by an adhesive layer, the method comprising: cutting the laminated glass structure (10; 142) with an abrasive cutting jet comprising a pressurized cutting fluid and abrasive particles thereby forming a shaped laminated glass structure (10; 142); wherein the average diameter of the abrasive particles is less than 1/4 of the thickness of the flexible glass sheet (14; 146). cutting the laminated glass structure (10; 142) with an abrasive cutting jet comprising a pressurized cutting fluid and abrasive particles thereby forming a shaped laminated glass structure (10; 142); wherein the average diameter of the abrasive particles is less than 1/4 of the thickness of the flexible glass sheet (14; 146).
A compound represented by the general formula or a pharmaceutically acceptable salt thereof: wherein p is 1 or 2; R 1 is a C1-C6 alkyl group which may have 1 to 3 substituents selected from substituent group α, or a C3-C7 cycloalkyl group which may have 1 to 3 substituents selected from substituent group β; substituent group α is the group consisting of a halogen atom, a hydroxyl group, a C1-C6 alkoxy group, a C3-C7 cycloalkyl group which may have 1 to 3 substituents selected from substituent group β, an amino group, a mono- or di(C1-C6 alkyl)amino group, an aryl group which may have 1 to 3 substituents selected from substituent group β, and a heteroaryl group which may have 1 to 3 substituents selected from substituent group β; substituent group β is the group consisting of a halogen atom, a hydroxyl group, a C1-C6 alkyl group, and a C1-C6 alkoxy group; m is 0; whereby each R 2 is absent; n is 0; whereby each R 3 is absent; R 4 is a hydrogen atom; R 5 is a hydrogen atom; R 6 is -C O-R 6a; R 6a is a C1-C6 alkyl group which may have 1 to 3 substituents selected from substituent group α, a C3-C7 cycloalkyl group which may have 1 to 3 substituents selected from substituent group β, an aryl group which may have 1 to 3 substituents selected from substituent group β, or a heteroaryl group which may have 1 to 3 substituents selected from substituent group β; and R 7 is a hydrogen atom, a halogen atom, or a C1-C6 alkyl group. p is 1 or 2; R 1 is a C1-C6 alkyl group which may have 1 to 3 substituents selected from substituent group α, or a C3-C7 cycloalkyl group which may have 1 to 3 substituents selected from substituent group β; substituent group α is the group consisting of a halogen atom, a hydroxyl group, a C1-C6 alkoxy group, a C3-C7 cycloalkyl group which may have 1 to 3 substituents selected from substituent group β, an amino group, a mono- or di(C1-C6 alkyl)amino group, an aryl group which may have 1 to 3 substituents selected from substituent group β, and a heteroaryl group which may have 1 to 3 substituents selected from substituent group β; substituent group β is the group consisting of a halogen atom, a hydroxyl group, a C1-C6 alkyl group, and a C1-C6 alkoxy group; m is 0; whereby each R 2 is absent; n is 0; whereby each R 3 is absent; R 4 is a hydrogen atom; R 5 is a hydrogen atom; R 6 is -C O-R 6a; R 6a is a C1-C6 alkyl group which may have 1 to 3 substituents selected from substituent group α, a C3-C7 cycloalkyl group which may have 1 to 3 substituents selected from substituent group β, an aryl group which may have 1 to 3 substituents selected from substituent group β, or a heteroaryl group which may have 1 to 3 substituents selected from substituent group β; and R 7 is a hydrogen atom, a halogen atom, or a C1-C6 alkyl group.
A trip unit for a circuit breaker, where the circuit breaker has at least one sensor configured for monitoring a current in a protected circuit and has an electromechanical tripping system, the trip unit comprising: a first controller arranged to be operably coupled to receive a current signal from the at least one sensor, and electrically coupled to the electromechanical tripping system, the first controller including a first processor responsive to executable computer instructions for transmitting a first signal to the electromechanical tripping system in response to a detection of a first current condition; and a second controller arranged to be operably coupled in parallel with the first controller to receive the current signal from the at least one sensor, and electrically coupled to the electromechanical tripping system, the second controller including a second processor responsive to executable computer instructions for detecting the first current condition and for classifying the first current condition and transmitting a second signal to the electromechanical tripping system after a predetermined first time period from the transmitting of the first signal, where the predetermined first time period is determined by the classification of the first current condition; wherein the first processor measures the current signal at a first accuracy level and the second processor measures the current signal at a second accuracy level, the first accuracy level being higher than the second accuracy level. a first controller arranged to be operably coupled to receive a current signal from the at least one sensor, and electrically coupled to the electromechanical tripping system, the first controller including a first processor responsive to executable computer instructions for transmitting a first signal to the electromechanical tripping system in response to a detection of a first current condition; and a second controller arranged to be operably coupled in parallel with the first controller to receive the current signal from the at least one sensor, and electrically coupled to the electromechanical tripping system, the second controller including a second processor responsive to executable computer instructions for detecting the first current condition and for classifying the first current condition and transmitting a second signal to the electromechanical tripping system after a predetermined first time period from the transmitting of the first signal, where the predetermined first time period is determined by the classification of the first current condition; wherein the first processor measures the current signal at a first accuracy level and the second processor measures the current signal at a second accuracy level, the first accuracy level being higher than the second accuracy level.
A medical ultrasound device for delivering non-contact ultrasound therapies to a skin, mucosa, or other tissue affected by a wound, ulcer, or other condition, the device comprising: at least one treatment wand comprising an ultrasonic transducer; at least one reservoir that contains a fluid comprising a micronized cellular or biological material; and a pump that is in fluid communication with the reservoir and the treatment wand to deliver the fluid to the treatment wand such that the ultrasonic transducer forms the fluid including the cellular or biological material into a mist as the fluid passes through the treatment wand for delivery to the skin, mucosa, or other tissue. at least one treatment wand comprising an ultrasonic transducer; at least one reservoir that contains a fluid comprising a micronized cellular or biological material; and a pump that is in fluid communication with the reservoir and the treatment wand to deliver the fluid to the treatment wand such that the ultrasonic transducer forms the fluid including the cellular or biological material into a mist as the fluid passes through the treatment wand for delivery to the skin, mucosa, or other tissue.