Mathematical problem solving circuit (100; 1000), comprising: a crosspoint matrix (M G; M G ou) including a plurality of row conductors (L i), a plurality of column conductors (C j; C ouj) and a plurality of resistive elements (Gij; Xij) each connected between a row conductor and column conductor; a plurality of operational amplifiers (OA i; OAouj), each having: a first input terminal (IN1i; "+") connected to a respective row conductor (L i), a second input terminal (IN2i;"-") connected to a ground terminal and an output terminal (OUi; OUPj) connected to a respective column; each operational amplifier (OA i; OAouj) of the plurality is in closed-loop configuration and comprises a respective output terminal (OUi; OUPj) connected to a respective column conductor (C j; C ouj) which is connected to the respective row conductor to perform the closed-loop configuration and being such to bring the respective first input terminal (IN1i; "+") towards a virtual ground; wherein: the plurality of resistive elements represents, by respective conductance values (Gij; Xij), a first plurality of known values of a mathematical problem; at least one configurable electric quantity (Ii; λG0; Go) for representing at least one second known value of the mathematical problem is associated with the circuit; the plurality of operational amplifiers (OAi; OAouj) defining from the respective output terminals (OUi; OUPj) a plurality of output voltages (V i; wi) representative of a plurality of solution values of the mathematical problem; the circuit is configured so as that the plurality of output voltages (Vi; wi) representative of the plurality of solution values are assumed when said first input terminals (IN1i; "+") assume the virtual ground. a crosspoint matrix (M G; M G ou) including a plurality of row conductors (L i), a plurality of column conductors (C j; C ouj) and a plurality of resistive elements (Gij; Xij) each connected between a row conductor and column conductor; a plurality of operational amplifiers (OA i; OAouj), each having: a first input terminal (IN1i; "+") connected to a respective row conductor (L i), a second input terminal (IN2i;"-") connected to a ground terminal and an output terminal (OUi; OUPj) connected to a respective column; each operational amplifier (OA i; OAouj) of the plurality is in closed-loop configuration and comprises a respective output terminal (OUi; OUPj) connected to a respective column conductor (C j; C ouj) which is connected to the respective row conductor to perform the closed-loop configuration and being such to bring the respective first input terminal (IN1i; "+") towards a virtual ground; wherein: the plurality of resistive elements represents, by respective conductance values (Gij; Xij), a first plurality of known values of a mathematical problem; at least one configurable electric quantity (Ii; λG0; Go) for representing at least one second known value of the mathematical problem is associated with the circuit; the plurality of operational amplifiers (OAi; OAouj) defining from the respective output terminals (OUi; OUPj) a plurality of output voltages (V i; wi) representative of a plurality of solution values of the mathematical problem; the circuit is configured so as that the plurality of output voltages (Vi; wi) representative of the plurality of solution values are assumed when said first input terminals (IN1i; "+") assume the virtual ground. the plurality of resistive elements represents, by respective conductance values (Gij; Xij), a first plurality of known values of a mathematical problem; at least one configurable electric quantity (Ii; λG0; Go) for representing at least one second known value of the mathematical problem is associated with the circuit; the plurality of operational amplifiers (OAi; OAouj) defining from the respective output terminals (OUi; OUPj) a plurality of output voltages (V i; wi) representative of a plurality of solution values of the mathematical problem; the circuit is configured so as that the plurality of output voltages (Vi; wi) representative of the plurality of solution values are assumed when said first input terminals (IN1i; "+") assume the virtual ground.