mhurhangee/ep-ind-claims huggingface dataset:
A monoclonal antibody which comprises a heavy chain constant region which is IgG2 wherein valine at position 234, glycine at position 237 and proline at position 331 are at least substituted with alanine, alanine and serine, respectively (numbering is based on the EU index of Kabat et al); has an agonist activity; and binds to human CD40, comprising a heavy chain variable region comprising CDR1, CDR2 and CDR3 represented by SEQ ID NOs: 6, 8 and 10, respectively, and a light chain variable region comprising CDR1, CDR2 and CDR3 represented by SEQ ID NOs:16, 18 and 20, respectively.
An electric work vehicle comprising: a hydraulic cylinder (45, 46, 47); a work oil feeding section for feeding work oil to the hydraulic cylinder; and an electric motor (6, 9); wherein the work oil feeding section includes a heating section for heating the work oil with using heat generated from the electric motor, the electric work vehicle further comprising: a control section for effecting an oil temperature adjustment operation for heating the work oil by controlling the work oil feeding section; the electric work vehicle being further characterised by a traveling motor for driving a traveling device as the electric motor; a power feeding section for feeding electric power to the traveling motor; and the control section causing the power feeding section to feed electric power to the traveling motor when the oil temperature adjustment operation is effected. a hydraulic cylinder (45, 46, 47); a work oil feeding section for feeding work oil to the hydraulic cylinder; and an electric motor (6, 9); wherein the work oil feeding section includes a heating section for heating the work oil with using heat generated from the electric motor, the electric work vehicle further comprising: a control section for effecting an oil temperature adjustment operation for heating the work oil by controlling the work oil feeding section; the electric work vehicle being further characterised by a traveling motor for driving a traveling device as the electric motor; a power feeding section for feeding electric power to the traveling motor; and the control section causing the power feeding section to feed electric power to the traveling motor when the oil temperature adjustment operation is effected. a control section for effecting an oil temperature adjustment operation for heating the work oil by controlling the work oil feeding section; the electric work vehicle being further characterised by a traveling motor for driving a traveling device as the electric motor; a power feeding section for feeding electric power to the traveling motor; and the control section causing the power feeding section to feed electric power to the traveling motor when the oil temperature adjustment operation is effected.
System for measuring pressure and temperature of a fluid, comprising at least one sensor unit and at least one releasably insertable tube, wherein the tube comprises a first section and a second section, wherein the first section is configured as a metal sleeve, and wherein the second section is a resilient section configured to provide a deformation response indicative of a fluid pressure, wherein the sensor unit comprises a temperature sensor, a pressure sensor, and a receiving area for releasably receiving the tube conveying the fluid, wherein the temperature sensor comprises a first contact portion adapted to contact the outer shape of the first section, wherein the pressure sensor comprises a second contact portion adapted to contact the outer shape of the second section, and wherein the first contact portion and the second contact portion at least partially define and/or adjoin the receiving area. wherein the first section is configured as a metal sleeve, and wherein the second section is a resilient section configured to provide a deformation response indicative of a fluid pressure,
An elongated lighting module defining a longitudinal axis and comprising: - a housing having a base at a base side and a light transmissive cover comprising a light transmissive cover top at a top side opposite said base side and a light transmissive wall extending between the top side and the base side, - an array of LEDs accommodated in a space enclosed by the base and the cover and facing away from the base side, - a mounting element for suspended connection via a suspension element to a ceiling defining in suspended arrangement a suspension axis, the mounting element extending over essentially the full length of the module, centrally intersecting, or extending over an outer surface of, or directly connected to the cover top and enabling the suspension element to be displaceable along the longitudinal axis, and the transparent cover facing towards the suspension element and extending over essentially the whole width of the housing and portions of side walls of the housing either as one cover or as two intersected elongated cover parts (39a,39b) axially extending mutually parallel and next to each other. - a housing having a base at a base side and a light transmissive cover comprising a light transmissive cover top at a top side opposite said base side and a light transmissive wall extending between the top side and the base side, - an array of LEDs accommodated in a space enclosed by the base and the cover and facing away from the base side, - a mounting element for suspended connection via a suspension element to a ceiling defining in suspended arrangement a suspension axis, the mounting element extending over essentially the full length of the module, centrally intersecting, or extending over an outer surface of, or directly connected to the cover top and enabling the suspension element to be displaceable along the longitudinal axis, and the transparent cover facing towards the suspension element and extending over essentially the whole width of the housing and portions of side walls of the housing either as one cover or as two intersected elongated cover parts (39a,39b) axially extending mutually parallel and next to each other.
Cargo hold of an aircraft, comprising: - cladding elements which are attached to supports, in particular structural elements, of the aircraft, wherein the cladding elements have a plurality of cladding holes with predefined cladding hole spacings (dV) for attachment, and - at least one housing element (10,20,30) for accommodating electronic components and/or cables, characterized in that the housing element (10, 20, 30) has at least one pair of housing holes for receiving fastening devices, wherein the housing holes have a housing hole spacing (dG) corresponding to at least one pair of cladding hole spacings (dV). - cladding elements which are attached to supports, in particular structural elements, of the aircraft, wherein the cladding elements have a plurality of cladding holes with predefined cladding hole spacings (dV) for attachment, and - at least one housing element (10,20,30) for accommodating electronic components and/or cables,
A shroud and shroud hanger assembly for a gas turbine engine, said assembly comprising: a shroud hanger assembly formed of a first material having a first coefficient of thermal expansion, said shroud hanger assembly having a forward hanger portion and a separate aftward hanger portion; and said aftward hanger portion including a diagonal web member extending from a radially inner end of a forward radially extending leg to a radially outer end of an aftward radially extending leg; a shroud formed of a second material having a second coefficient of thermal expansion, said shroud comprising a forward radially extending wall, an aftward radially extending wall, and a body extending axially therebetween; said forward hanger portion and said aftward hanger portion configured to couple together to clamp said forward radially extending wall of said shroud between said forward hanger portion and said forward radially extending leg of said aftward hanger portion. a shroud hanger assembly formed of a first material having a first coefficient of thermal expansion, said shroud hanger assembly having a forward hanger portion and a separate aftward hanger portion; and said aftward hanger portion including a diagonal web member extending from a radially inner end of a forward radially extending leg to a radially outer end of an aftward radially extending leg; a shroud formed of a second material having a second coefficient of thermal expansion, said shroud comprising a forward radially extending wall, an aftward radially extending wall, and a body extending axially therebetween; said forward hanger portion and said aftward hanger portion configured to couple together to clamp said forward radially extending wall of said shroud between said forward hanger portion and said forward radially extending leg of said aftward hanger portion.
A process for producing moldings, where the mixture comprising at least one lactam at least one catalyst at least one activator selected from the group of lactams N-substituted by electrophilic radicals, aliphatic diisocyanates, aromatic diisocyanates, polyisocyanates, aliphatic diacyl halides and aromatic diacyl halides optionally at least one additional substance selected from fillers and/or fibers, polymers and further additives proceeds through treatments comprising a) mixing of,,, and optionally b) metering of the mixture into an apparatus for producing mixture droplets comprising,,, and optionally and producing mixture droplets, c) depositing the mixture droplets on a belt, and d) producing moldings where the steps a), b), and c) are conducted independently of one another at a temperature which is in the range from the melting point of the highest-melting-point lactam comprised in the mixture to 100°C above the melting point of the highest-melting-point lactam comprised in the mixture, and wherein the belt onto which the mixture droplets are deposited in step c) is cooled to a temperature in the range from 100°C below the melting point of, and and optionally to 20°C below the melting point of, and and optionally and wherein the belt is moved at a speed of 1 to 20 m/min and wherein the longest axis of the moldings is in the range from 0.05 to 15 mm and the shortest axis of the moldings is in the range from 0.05 to 15 mm, wherein the length of the axes is measured under the microscope on ten randomly selected particles. at least one lactam at least one catalyst at least one activator selected from the group of lactams N-substituted by electrophilic radicals, aliphatic diisocyanates, aromatic diisocyanates, polyisocyanates, aliphatic diacyl halides and aromatic diacyl halides optionally at least one additional substance selected from fillers and/or fibers, polymers and further additives a) mixing of,,, and optionally b) metering of the mixture into an apparatus for producing mixture droplets comprising,,, and optionally and producing mixture droplets, c) depositing the mixture droplets on a belt, and d) producing moldings
A method of making a flexible plasma-based film comprising the steps of: (a) mixing blood plasma with one or two activators of the coagulation system selected from: more than 2.5 International Units of thrombin per milliliter (ml) of said plasma; and 0.65 to 1.3 mg of calcium ions per milliliter (ml) of said plasma, to induce clotting of said plasma, wherein said plasma is contained within a mold; and (b) maintaining said plasma in said mold for the time required for the plasma to clot and to form said film, wherein optionally during or at the end of said time a pressure is applied to said plasma in said mold. (a) mixing blood plasma with one or two activators of the coagulation system selected from: more than 2.5 International Units of thrombin per milliliter (ml) of said plasma; and 0.65 to 1.3 mg of calcium ions per milliliter (ml) of said plasma, to induce clotting of said plasma, wherein said plasma is contained within a mold; and (b) maintaining said plasma in said mold for the time required for the plasma to clot and to form said film, wherein optionally during or at the end of said time a pressure is applied to said plasma in said mold.
At least one TGF-beta2 antisense oligonucleotide of SEQ ID NO: 30 or its active derivative which is a morpholino oligonucleotide, or comprises a locked nucleic acid, or comprises 1 to 20 additional nucleotides at the 3'- and/or 5'-end, for use in inhibiting the formation of metastasis in pancreatic cancer.
Device for at least partially closing an opening of a cooking vessel, comprising a support element which can be brought to rest on an opening edge of the opening of the cooking vessel, and a plug-in element which can be at least partially inserted through the opening, wherein the plug-in element has a blocking means which can be brought into a blocking position in which the blocking means interacts with the opening edge so that a withdrawal of the plug-in element is essentially prevented, characterized in that, in the blocking position, a free space is formed at least in regions around the plug-in element, as a result of which the plug-in element can be moved in the direction of the opening edge, so that the blocking means can be brought into a release position in which the blocking means can be released at least partially from the opening edge.
A composition comprising: a plurality of diodes, a first solvent and a viscosity modifier; wherein each diode of the plurality of diodes comprises: a light emitting or absorbing region having a lateral dimension between 6 and 30 microns and a height between 1 and 7 microns; a first terminal coupled to the light emitting region on a first side; and a second terminal (105, 127) coupled to the light emitting region on a second side opposite the first side, the first and second terminals having a height between 1 and 6 microns; wherein each diode of the plurality of diodes is substantially hexagonal laterally, has a lateral dimension between 10 and 50 microns measured opposing face-to-face, and a height between 5 and 25 microns; the composition being characterised in that the lateral sides of each diode of the plurality of diodes are substantially sigmoidal and terminate in a curved point. a plurality of diodes, a first solvent and a viscosity modifier; wherein each diode of the plurality of diodes comprises: a light emitting or absorbing region having a lateral dimension between 6 and 30 microns and a height between 1 and 7 microns; a first terminal coupled to the light emitting region on a first side; and a second terminal (105, 127) coupled to the light emitting region on a second side opposite the first side, the first and second terminals having a height between 1 and 6 microns; wherein each diode of the plurality of diodes is substantially hexagonal laterally, has a lateral dimension between 10 and 50 microns measured opposing face-to-face, and a height between 5 and 25 microns; a light emitting or absorbing region having a lateral dimension between 6 and 30 microns and a height between 1 and 7 microns; a first terminal coupled to the light emitting region on a first side; and a second terminal (105, 127) coupled to the light emitting region on a second side opposite the first side, the first and second terminals having a height between 1 and 6 microns; wherein each diode of the plurality of diodes is substantially hexagonal laterally, has a lateral dimension between 10 and 50 microns measured opposing face-to-face, and a height between 5 and 25 microns; the composition being characterised in that the lateral sides of each diode of the plurality of diodes are substantially sigmoidal and terminate in a curved point.
A method for preparing a product comprising: 1) combining starting materials comprising A) a boron containing Lewis acid; B) a hydroxyl terminated polydiorganosiloxane of formula where subscript n is 2 to 2,000, and each R 1 is independently selected from the group consisting of monovalent hydrocarbon groups and monovalent halogenated hydrocarbon groups; and C) a cyclic polyorganohydrogensiloxane of formula (RHSiO 2/2) v, where subscript v is 3 to 12; and each R is an independently selected monovalent hydrocarbon group; thereby preparing the product comprising a polyfunctional organohydrogensiloxane and a by-product comprising H 2; and 2) combining a) the polyfunctional organohydrogensiloxane, b) a hydrosilylation reaction catalyst, and c) a reactive species having an average, per molecule at least one aliphatically unsaturated group capable of undergoing an addition reaction with a silicon bonded hydrogen atom of starting material a) and further comprising one or more curable groups per molecule. 1) combining starting materials comprising A) a boron containing Lewis acid; B) a hydroxyl terminated polydiorganosiloxane of formula where subscript n is 2 to 2,000, and each R 1 is independently selected from the group consisting of monovalent hydrocarbon groups and monovalent halogenated hydrocarbon groups; and C) a cyclic polyorganohydrogensiloxane of formula (RHSiO 2/2) v, where subscript v is 3 to 12; and each R is an independently selected monovalent hydrocarbon group; thereby preparing the product comprising a polyfunctional organohydrogensiloxane and a by-product comprising H 2; and A) a boron containing Lewis acid; B) a hydroxyl terminated polydiorganosiloxane of formula where subscript n is 2 to 2,000, and each R 1 is independently selected from the group consisting of monovalent hydrocarbon groups and monovalent halogenated hydrocarbon groups; and C) a cyclic polyorganohydrogensiloxane of formula (RHSiO 2/2) v, where subscript v is 3 to 12; and each R is an independently selected monovalent hydrocarbon group; thereby preparing the product comprising a polyfunctional organohydrogensiloxane and a by-product comprising H 2; and 2) combining a) the polyfunctional organohydrogensiloxane, b) a hydrosilylation reaction catalyst, and c) a reactive species having an average, per molecule at least one aliphatically unsaturated group capable of undergoing an addition reaction with a silicon bonded hydrogen atom of starting material a) and further comprising one or more curable groups per molecule. a) the polyfunctional organohydrogensiloxane, b) a hydrosilylation reaction catalyst, and c) a reactive species having an average, per molecule at least one aliphatically unsaturated group capable of undergoing an addition reaction with a silicon bonded hydrogen atom of starting material a) and further comprising one or more curable groups per molecule.
A biocompatible scaffold for multi-dimensional cultivation of cells, said scaffolds capable of automechanoinduction and comprising: - highly aligned fibers oriented to form a scaffold with open porosity in a range of 70-99%, preferably 85-95% for the cultured cells, wherein the fibers have a diameter of 20-100 nm, and an aspect ratio more than 10000:1 calculated as length divided by diameter of the fibers, - said fibers being made of non-cytotoxic, non-carcinogenic inorganic metal oxide, and - said fibers being self-aligned into the scaffold during its manufacturing process. - highly aligned fibers oriented to form a scaffold with open porosity in a range of 70-99%, preferably 85-95% for the cultured cells, wherein the fibers have a diameter of 20-100 nm, and an aspect ratio more than 10000:1 calculated as length divided by diameter of the fibers, - said fibers being made of non-cytotoxic, non-carcinogenic inorganic metal oxide, and - said fibers being self-aligned into the scaffold during its manufacturing process.
Device for regulating the level of a driver's cab of a utility vehicle relative to a vehicle frame, characterised in that between the driver's cab and the vehicle frame four electrically operated spindle drives (8, 8a, 8b, 8c, 8d, 9, 10), which are controllable separately from one another by means of a control device and adjust a variable lift, are arranged with two mutually displaceable components (13, 13c, 14, 14c), wherein a cartridge receiving the spindle drive and a sleeve connected to the spindle of the spindle drive are guided into one another in an axially displaceable manner.
Non-linear superconducting quantum circuit comprising: a first resonant portion (30; 70) comprising at least one inductance (300; 700) and at least one capacitor (302; 702); a second resonant portion (32; 72) comprising at least one inductance (320; 720) and at least one capacitor (322; 722); and an asymmetrical threaded superconducting quantum interference device being arranged between said first resonant portion (30; 70) and said second resonant portion (32; 72), said non-linear superconducting quantum circuit being characterized in that said asymmetrical threaded superconducting quantum interference device is connected to both said first resonant portion (30; 70) and said second resonant portion (32; 72) galvanically, said non-linear superconducting circuit hosts a first mode (a) with a first resonant frequency in said first resonant portion (30; 70) and hosts a second mode (b) with a second resonant frequency in said second resonant portion (32; 72), the ratio between said first resonant frequency and said second resonant frequency is different from 1⁄2, said first resonant portion (30; 70) and said second resonant portion (32; 72) are configured with inductance and capacitance values which induce with said asymmetrical threaded superconducting quantum interference device said first mode (a) and said second mode (b) such that said non-linear superconducting quantum circuit has zero-point fluctuations of the superconducting phase across the asymmetrical threaded superconducting quantum interference device for the first mode (a) and the second mode (b) which are superior or equal to 0.05 rad. a first resonant portion (30; 70) comprising at least one inductance (300; 700) and at least one capacitor (302; 702); a second resonant portion (32; 72) comprising at least one inductance (320; 720) and at least one capacitor (322; 722); and an asymmetrical threaded superconducting quantum interference device being arranged between said first resonant portion (30; 70) and said second resonant portion (32; 72), said non-linear superconducting quantum circuit being characterized in that said asymmetrical threaded superconducting quantum interference device is connected to both said first resonant portion (30; 70) and said second resonant portion (32; 72) galvanically, said non-linear superconducting circuit hosts a first mode (a) with a first resonant frequency in said first resonant portion (30; 70) and hosts a second mode (b) with a second resonant frequency in said second resonant portion (32; 72), the ratio between said first resonant frequency and said second resonant frequency is different from 1⁄2, said first resonant portion (30; 70) and said second resonant portion (32; 72) are configured with inductance and capacitance values which induce with said asymmetrical threaded superconducting quantum interference device said first mode (a) and said second mode (b) such that said non-linear superconducting quantum circuit has zero-point fluctuations of the superconducting phase across the asymmetrical threaded superconducting quantum interference device for the first mode (a) and the second mode (b) which are superior or equal to 0.05 rad.
Compressor device for compressing gas that comprises a compressor element with a housing with an inlet and an outlet, whereby at least one rotor is affixed in the housing that is provided with a drive, whereby the compressor device is provided with an oil circuit for injecting oil into the housing, whereby the oil circuit only comprises one pump for driving the oil around in the oil circuit, whereby this pump is coupled to a first shaft via a first disengageable coupling, more specifically a shaft of the aforementioned drive on the one hand, characterized in that the first coupling is disengageable; and the pump is further driven by a second shaft via a second disengageable coupling, more specifically a shaft of a secondary drive on the other hand, whereby the first and second disengageable couplings (24, 28) between the pump and the first shaft and between the pump and the second shaft are such that the pump is only driven by the shaft of these two shafts (9, 27) that has the highest speed.