A respiratory therapy system comprising: a pressure generator configured to generate a pressurized flow of breathable gas for delivery to the airway of a subject; one or more sensors configured to generate one or more output signals conveying information related to one or more gas parameters of the pressurized flow of breathable gas; and one or more processors configured to execute computer program modules, the computer program modules comprising: a trigger module configured to detect trigger events indicating respiratory effort by the subject based on the one or more output signals and one or more trigger parameters, wherein the one or more trigger parameters are adjustable to facilitate detection of the trigger events with different levels of trigger sensitivity; and a control module configured to control the pressure generator to adjust one or more gas parameters of the pressurized flow of breathable gas as a function of time in accordance with a respiratory therapy regime, wherein the respiratory therapy regime dictates adjustments to the one or more gas parameters based on the detected trigger events, characterized in that the computer program modules further comprise: a muscle pressure module configured to determine a muscle pressure of the subject based on the one or more output signals; an error detection module configured to detect one or both of an ineffective trigger event and/or a false trigger event, wherein one or both detections by the error detection module are based on the determined muscle pressure; a sensitivity module configured to adjust the one or more trigger parameters to adjust the trigger sensitivity based on one or more detections by the error detection module. a pressure generator configured to generate a pressurized flow of breathable gas for delivery to the airway of a subject; one or more sensors configured to generate one or more output signals conveying information related to one or more gas parameters of the pressurized flow of breathable gas; and one or more processors configured to execute computer program modules, the computer program modules comprising: a trigger module configured to detect trigger events indicating respiratory effort by the subject based on the one or more output signals and one or more trigger parameters, wherein the one or more trigger parameters are adjustable to facilitate detection of the trigger events with different levels of trigger sensitivity; and a control module configured to control the pressure generator to adjust one or more gas parameters of the pressurized flow of breathable gas as a function of time in accordance with a respiratory therapy regime, wherein the respiratory therapy regime dictates adjustments to the one or more gas parameters based on the detected trigger events, a trigger module configured to detect trigger events indicating respiratory effort by the subject based on the one or more output signals and one or more trigger parameters, wherein the one or more trigger parameters are adjustable to facilitate detection of the trigger events with different levels of trigger sensitivity; and a control module configured to control the pressure generator to adjust one or more gas parameters of the pressurized flow of breathable gas as a function of time in accordance with a respiratory therapy regime, wherein the respiratory therapy regime dictates adjustments to the one or more gas parameters based on the detected trigger events, characterized in that the computer program modules further comprise: a muscle pressure module configured to determine a muscle pressure of the subject based on the one or more output signals; an error detection module configured to detect one or both of an ineffective trigger event and/or a false trigger event, wherein one or both detections by the error detection module are based on the determined muscle pressure; a sensitivity module configured to adjust the one or more trigger parameters to adjust the trigger sensitivity based on one or more detections by the error detection module. a muscle pressure module configured to determine a muscle pressure of the subject based on the one or more output signals; an error detection module configured to detect one or both of an ineffective trigger event and/or a false trigger event, wherein one or both detections by the error detection module are based on the determined muscle pressure; a sensitivity module configured to adjust the one or more trigger parameters to adjust the trigger sensitivity based on one or more detections by the error detection module.