A compound represented by the structure of Formula I: Wherein in Formula I: A is COR 1; R 1 is a heteroaryloxy; R 2 is selected from the group consisting of hydrogen, unsubstituted or substituted C 1 -C 12 alkyl, unsubstituted or substituted C 3 -C 8 cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heteroaryl, OR 8, oxo and NR 9a R 9b; R 3, R 4, R 5, R 6 and R 7 are each independently selected from the group consisting of hydrogen, unsubstituted or substituted C 1 -C 12 alkyl, unsubstituted or substituted C 1 -C 12 haloalkyl, unsubstituted or substituted C 3 -C 8 cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heteroaryl, OR 8 and NR 9a R 9b, or and R 6 together with the carbons to which they are attached form a C 3 -C 8 cycloalkyl or a C 3 -C 8 cycloalkyl substituted by halo; or one of R 5 and R 6 represents an oxygen atom which is bonded to C 6, thereby forming an oxygen-containing 6 or 5 membered heterocyclic ring, respectively; wherein the bond between C 9 and C 10 can be a single or double bond; R 8, R 9a and R 9b are each independently selected from the group consisting of hydrogen, unsubstituted or substituted C 1 -C 12 alkyl, unsubstituted or substituted C 3 -C 8 cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heteroaryl, glucosyl, or R 9a and R 9b can together with the nitrogen to which they are attached form an unsubstituted or substituted heterocyclic or heteroaromatic ring optionally containing one or more additional heteroatom selected from O, N and S; and n is selected from O. 1 and 2; including salts, hydrates, solvates, polymorphs, optical isomers, geometrical isomers, enantiomers, diastereomers, and mixtures thereof. A is COR 1; R 1 is a heteroaryloxy; R 2 is selected from the group consisting of hydrogen, unsubstituted or substituted C 1 -C 12 alkyl, unsubstituted or substituted C 3 -C 8 cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heteroaryl, OR 8, oxo and NR 9a R 9b; R 3, R 4, R 5, R 6 and R 7 are each independently selected from the group consisting of hydrogen, unsubstituted or substituted C 1 -C 12 alkyl, unsubstituted or substituted C 1 -C 12 haloalkyl, unsubstituted or substituted C 3 -C 8 cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heteroaryl, OR 8 and NR 9a R 9b, or and R 6 together with the carbons to which they are attached form a C 3 -C 8 cycloalkyl or a C 3 -C 8 cycloalkyl substituted by halo; or one of R 5 and R 6 represents an oxygen atom which is bonded to C 6, thereby forming an oxygen-containing 6 or 5 membered heterocyclic ring, respectively; wherein the bond between C 9 and C 10 can be a single or double bond; R 8, R 9a and R 9b are each independently selected from the group consisting of hydrogen, unsubstituted or substituted C 1 -C 12 alkyl, unsubstituted or substituted C 3 -C 8 cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted heteroaryl, glucosyl, or R 9a and R 9b can together with the nitrogen to which they are attached form an unsubstituted or substituted heterocyclic or heteroaromatic ring optionally containing one or more additional heteroatom selected from O, N and S; and n is selected from O. 1 and 2;