A vacuum insulation glass panel assembly manufacturing method, comprising: an edge sealing step of sealing an edge of a glass panel assembly of glass panels (12, 14) spaced apart at a predetermined interval; and an exhaust port sealing step of causing a lid member to seal an exhaust port of the glass panel assembly formed so as to communicate with a space between the glass panels (12, 14) whose edges are sealed, wherein in the edge sealing step, a glass panel assembly obtained by applying a first sealing agent having a high melting point to edges of the glass panels (12, 14) spaced apart at a predetermined interval is put into a first heating chamber and is heated to melt the first sealing agent to seal the edge of the glass panel assembly, and the exhaust port sealing step includes: a step of mounting a lid member closing device mounted with a lid member having one surface coated with a second sealing agent having a low melting point on the glass panel assembly having a sealed edge so that the lid member is disposed around the exhaust port of the glass panel assembly so as to be spaced apart by a predetermined distance; a step of putting the edge-sealed glass panel assembly mounted with the lid member closing device into a second heating chamber and melting the second sealing agent coated on the lid member by heating the glass panel assembly to a temperature at which the first sealing agent having a high melting point is not melted and the second sealing agent having a low melting point is melted; a step of putting the glass panel assembly mounted with the lid member closing device into a first vacuum heating chamber kept in an atmospheric pressure state, heating the glass panel assembly to maintain the second sealing agent in a molten state, and depressurizing the first vacuum heating chamber so that an air is exhausted through the exhaust port of the glass panel assembly to form a vacuum in the space between the glass panels (12, 14); a lid member close contact step of, when moving the glass panel assembly to a second vacuum heating chamber communicating with the first vacuum heating chamber and remaining in a depressurized state, bringing the lid member mounted on the lid member closing device into close contact with a periphery of the exhaust port of the glass panel assembly by an external force acting on the lid member closing device to seal the exhaust port of the glass panel assembly; and a pressurizing step of, after putting the vacuum insulation glass panel assembly sealed by the lid member into the second vacuum heating chamber kept in a depressurized state, pressurizing the second vacuum heating chamber to an atmospheric pressure. an edge sealing step of sealing an edge of a glass panel assembly of glass panels (12, 14) spaced apart at a predetermined interval; and an exhaust port sealing step of causing a lid member to seal an exhaust port of the glass panel assembly formed so as to communicate with a space between the glass panels (12, 14) whose edges are sealed, wherein in the edge sealing step, a glass panel assembly obtained by applying a first sealing agent having a high melting point to edges of the glass panels (12, 14) spaced apart at a predetermined interval is put into a first heating chamber and is heated to melt the first sealing agent to seal the edge of the glass panel assembly, and the exhaust port sealing step includes: a step of mounting a lid member closing device mounted with a lid member having one surface coated with a second sealing agent having a low melting point on the glass panel assembly having a sealed edge so that the lid member is disposed around the exhaust port of the glass panel assembly so as to be spaced apart by a predetermined distance; a step of putting the edge-sealed glass panel assembly mounted with the lid member closing device into a second heating chamber and melting the second sealing agent coated on the lid member by heating the glass panel assembly to a temperature at which the first sealing agent having a high melting point is not melted and the second sealing agent having a low melting point is melted; a step of putting the glass panel assembly mounted with the lid member closing device into a first vacuum heating chamber kept in an atmospheric pressure state, heating the glass panel assembly to maintain the second sealing agent in a molten state, and depressurizing the first vacuum heating chamber so that an air is exhausted through the exhaust port of the glass panel assembly to form a vacuum in the space between the glass panels (12, 14); a lid member close contact step of, when moving the glass panel assembly to a second vacuum heating chamber communicating with the first vacuum heating chamber and remaining in a depressurized state, bringing the lid member mounted on the lid member closing device into close contact with a periphery of the exhaust port of the glass panel assembly by an external force acting on the lid member closing device to seal the exhaust port of the glass panel assembly; and a pressurizing step of, after putting the vacuum insulation glass panel assembly sealed by the lid member into the second vacuum heating chamber kept in a depressurized state, pressurizing the second vacuum heating chamber to an atmospheric pressure.