mhurhangee/ep-ind-claims huggingface dataset:
A fire protection sprinkler comprising: a body having an inlet orifice, an outlet orifice, and an interior surface that defines a water passage between the inlet orifice and the outlet orifice; a seal cap configured to seal a flow of a fluid from the outlet orifice; a thermally-responsive element configured to releasably retain the seal cap in the outlet orifice; and a deflector supported on the body, wherein the fire protection sprinkler is characterized by: (a) the interior surface of the body being formed of or coated with one of polytetrafluoroethylene and fluorinated ethylene propylene, and (b) a water-exposed surface of the seal cap being formed of or coated with one of polytetrafluoroethylene and fluorinated ethylene propylene. a body having an inlet orifice, an outlet orifice, and an interior surface that defines a water passage between the inlet orifice and the outlet orifice; a seal cap configured to seal a flow of a fluid from the outlet orifice; a thermally-responsive element configured to releasably retain the seal cap in the outlet orifice; and a deflector supported on the body, wherein the fire protection sprinkler is characterized by: (a) the interior surface of the body being formed of or coated with one of polytetrafluoroethylene and fluorinated ethylene propylene, and (b) a water-exposed surface of the seal cap being formed of or coated with one of polytetrafluoroethylene and fluorinated ethylene propylene. (a) the interior surface of the body being formed of or coated with one of polytetrafluoroethylene and fluorinated ethylene propylene, and (b) a water-exposed surface of the seal cap being formed of or coated with one of polytetrafluoroethylene and fluorinated ethylene propylene.
A method for thermally treating a workpiece, comprising marking a predetermined area of a face side of the workpiece with unique identifiers by a first laser-generated beam; and heating an area of a backside of the workpiece across the predetermined area on the face side by a second laser-generated beam so as to minimize a deformation of the workpiece, the workpiece being metal or plastic and having a thickness of up to about two millimeters, wherein the laser generated beams are emitted by respective lasers, the method further comprising controlling a laser parameter selected from the group consisting of a focal spot diameter, power on workpiece, marking speed, line spacing, repetition rate, marking direction and pulse length, and a combination thereof.
An irreversible Btk inhibitor for use in the treatment of B-cell proliferative disorders which irreversible Btk inhibitor is of formula D: wherein: L a is CH 2, O, NH or S; Ar is a substituted or unsubstituted aryl, or a substituted or unsubstituted heteroaryl; Y is an optionally substituted group selected from among alkyl, heteroalkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl; Z is C(=O), OC(=O), NHC(=O), C(=S), S(=O) x, OS(=O) x, NHS(=O) x, where x is 1 or 2; R 7 and R 8 are independently selected from among H, unsubstituted C 1 -C 4 alkyl, substituted C 1 -C 4 alkyl. unsubstituted C 1 -C 4 heteroalkyl, substituted C 1 -C 4 heteroalkyl, unsubstituted C 3 -C 6 cycloalkyl, substituted C 3 -C 6 cycloalkyl, unsubstituted C 2 -C 6 heterocycloalkyl, and substituted C 2 -C 6 heterocycloalkyl; or R 7 and R 8 taken together form a bond; R 6 is H, substituted or unsubstituted C 1 -C 4 alkyl, substituted or unsubstituted C 1 -C 4 heteroalkyl, C 1 -C 8 alkoxyalkyl, C 1 -C 8 alkylaminoalkyl, substituted or unsubstituted C 3 -C 6 cycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted C 2 -C 8 heterocycloalkyl, substituted or unsubstituted heteroaryl, C 1 -C 4 alkyl(aryl), C 1 -C 4 alkyl(heteroaryl), C 1 -C 4 alkyl(C 3 -C 8 cycloalkyl), or C 1 -C 4 alkyl(C 2 -C 8 heterocycloalkyl); and pharmaceutically acceptable solvates or pharmaceutically acceptable salts thereof. L a is CH 2, O, NH or S; Ar is a substituted or unsubstituted aryl, or a substituted or unsubstituted heteroaryl; Y is an optionally substituted group selected from among alkyl, heteroalkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl; Z is C(=O), OC(=O), NHC(=O), C(=S), S(=O) x, OS(=O) x, NHS(=O) x, where x is 1 or 2; R 7 and R 8 are independently selected from among H, unsubstituted C 1 -C 4 alkyl, substituted C 1 -C 4 alkyl. unsubstituted C 1 -C 4 heteroalkyl, substituted C 1 -C 4 heteroalkyl, unsubstituted C 3 -C 6 cycloalkyl, substituted C 3 -C 6 cycloalkyl, unsubstituted C 2 -C 6 heterocycloalkyl, and substituted C 2 -C 6 heterocycloalkyl; or R 7 and R 8 taken together form a bond; R 6 is H, substituted or unsubstituted C 1 -C 4 alkyl, substituted or unsubstituted C 1 -C 4 heteroalkyl, C 1 -C 8 alkoxyalkyl, C 1 -C 8 alkylaminoalkyl, substituted or unsubstituted C 3 -C 6 cycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted C 2 -C 8 heterocycloalkyl, substituted or unsubstituted heteroaryl, C 1 -C 4 alkyl(aryl), C 1 -C 4 alkyl(heteroaryl), C 1 -C 4 alkyl(C 3 -C 8 cycloalkyl), or C 1 -C 4 alkyl(C 2 -C 8 heterocycloalkyl); and pharmaceutically acceptable solvates or pharmaceutically acceptable salts thereof.
A compound of formula I: wherein: X is N(C 1-4 alkyl), N or O; R 1 is H or C 1-6 alkyl (e.g., methyl); R 2 is H or OR 3 wherein R 3 is H or C 1-6 alkyl (e.g., methyl); provided that R 1 and R 2 are not both H, and R 1 and R 3 are not both H; in free or salt form. X is N(C 1-4 alkyl), N or O; R 1 is H or C 1-6 alkyl (e.g., methyl); R 2 is H or OR 3 wherein R 3 is H or C 1-6 alkyl (e.g., methyl); provided that R 1 and R 2 are not both H, and R 1 and R 3 are not both H;
A method used for fiber pairing in an optical fiber cable network, wherein the optical fiber cable network comprises at least two node devices, each node device comprises at least two direction-A ports or direction-B ports, the node devices are connected by using an optical cable, and both ends of each optical fiber comprised in the optical cable are respectively connected to a direction-A port of a node device and a direction-B port of another node device; characterized in that the method comprises: determining direction-A optical fiber lengths of the direction-A ports of each node device of the at least two node devices, and direction-B optical fiber lengths of the direction-B ports of each node device, wherein the direction-A optical fiber lengths of the direction-A ports of the node device are mutually different, and the direction-B optical fiber lengths of the direction-B ports of the node device are also mutually different; determining direction-A correspondences between the direction-A optical fiber lengths of each node device and the direction-A ports of the node device, and direction-B correspondences between the direction-B optical fiber lengths of each node device and the direction-B ports of the node device; and determining connection relationships between ports of different node devices of the at least two node devices according to connection relationships between the node devices of the at least two node devices, the direction-A correspondences, and the direction-B correspondences. determining direction-A optical fiber lengths of the direction-A ports of each node device of the at least two node devices, and direction-B optical fiber lengths of the direction-B ports of each node device, wherein the direction-A optical fiber lengths of the direction-A ports of the node device are mutually different, and the direction-B optical fiber lengths of the direction-B ports of the node device are also mutually different; determining direction-A correspondences between the direction-A optical fiber lengths of each node device and the direction-A ports of the node device, and direction-B correspondences between the direction-B optical fiber lengths of each node device and the direction-B ports of the node device; and determining connection relationships between ports of different node devices of the at least two node devices according to connection relationships between the node devices of the at least two node devices, the direction-A correspondences, and the direction-B correspondences.
A propulsion system for an aquatic vessel, wherein the propulsion system includes at least one Magnus-type rotor including a cylindrical body, which Magnus-type rotor is operable to rotate about a corresponding substantially upright axis, a drive arrangement for rotating the at least one Magnus-type rotor, and a control arrangement for controlling the drive arrangement for varying rates of rotation and/or direction of the at least one Magnus-type rotor, characterized in that the at least one Magnus-type rotor includes a hollow region therein, and is rotationally supported onto a support arrangement which extends into the hollow region, and at least one motor of the drive arrangement for rotating the at least one Magnus-type rotor is included in the hollow region and lies outside the support arrangement, and the at least one motor is accessible for maintenance, and the at least one Magnus-type rotor includes a ventilation aperture arrangement in the upper region of the rotor for enabling an upward movement of air into and out of the cylindrical body to occur in operation within the at least one Magnus-type rotor for ventilating and cooling the drive arrangement and/or other internal components.
A linear stepper motor comprising a rotor, two plain bearings (13, 15; 14, 16), two motor bearing shields (2, 3), a spindle nut, and a fork-shaped actuating rod; wherein the rotor comprises a rotor shaft that comprises a motive thread and is configured to drive a linearly guided actuator, the rotor shaft comprises plain bearing journals (11, 12) at ends thereof, which each comprise an end radially and axially enclosed in the plain bearings (13, 15; 14, 16) seated in the motor bearing shields (2, 3), and, by the motive thread, axially drives the spindle nut connected with the fork-shaped actuating rod in a rotation-proof manner; characterised in that the rotor shaft comprises a flexurally and torsionally rigid plastic threaded spindle with a plastic core with coaxially arranged metallic shaft ends so as to act as metallic journals on opposite ends for concurrent plain bearing support and axial support.
A magnetic pole detection system comprising: a magnetic pole array including a plurality of magnetic poles of N and S arranged alternately; a magnetic sensor array including a plurality of magnetic sensors (A to E) for detecting a magnetic pole of the magnetic pole array; a phase detection head for detecting a phase regarding one magnetic pole currently being detected by the magnetic sensor array in the magnetic pole array according to a signal from the magnetic sensor array; a pitch identification unit for identifying a pitch number of the magnetic pole currently being detected in the magnetic pole array; a plurality of marks arranged in parallel with the magnetic pole array, changing synchronously with the magnetic poles of the magnetic pole array; and the marks each being configured at least by the magnetic poles of the magnetic sensor array extended in a first direction perpendicular to a second direction in which the magnet poles of the magnet sensor array are arranged and magnetic poles of the magnet sensor array un-extended in the first direction; wherein the mark sensor array includes a plurality of mark detection sensors (A to E) provided in parallel with the magnetic sensor array; and the pitch identification unit identifies the pitch number of a magnetic pole in the magnet pole array based on unique combinations of signals from the mark detection sensors (A to E). a magnetic pole array including a plurality of magnetic poles of N and S arranged alternately; a magnetic sensor array including a plurality of magnetic sensors (A to E) for detecting a magnetic pole of the magnetic pole array; a phase detection head for detecting a phase regarding one magnetic pole currently being detected by the magnetic sensor array in the magnetic pole array according to a signal from the magnetic sensor array; a pitch identification unit for identifying a pitch number of the magnetic pole currently being detected in the magnetic pole array; a plurality of marks arranged in parallel with the magnetic pole array, changing synchronously with the magnetic poles of the magnetic pole array; and the marks each being configured at least by the magnetic poles of the magnetic sensor array extended in a first direction perpendicular to a second direction in which the magnet poles of the magnet sensor array are arranged and magnetic poles of the magnet sensor array un-extended in the first direction; wherein the mark sensor array includes a plurality of mark detection sensors (A to E) provided in parallel with the magnetic sensor array; and the pitch identification unit identifies the pitch number of a magnetic pole in the magnet pole array based on unique combinations of signals from the mark detection sensors (A to E).
A stable formulation for intracutaneous injection of a therapeutic agent, said formulation comprising an effective amount of said therapeutic agent in the form of particles, wherein said particles are homogeneously contained within a non-aqueous pharmaceutically acceptable carrier and comprise from 1.0 to 80 weight percent of the formulation, wherein said formulation has an injection volume of 0.1 to about 1000 microliters, and wherein said therapeutic agent and pharmaceutically acceptable carrier form a paste suitable for intracutaneous injection.
An active road-noise control system comprising: a sensor arrangement (301; 401) configured to generate a first sense signal representative of at least one of acceleration, motion and vibration that occurs at a first position on a vehicle body and a second sense signal representative of sound that occurs at a second position within the vehicle body; an active road-noise control module (108, 109) configured to provide a noise-reducing signal by processing the first sense signal and the second sense signal according to a first mode of operation or a second mode of operation; at least one loudspeaker (111; 114; 202) disposed at a third position within the vehicle body and configured to generate noise-reducing sound at the second position from the noise-reducing signal; and a malfunction detection module (115; 205; 306) configured to evaluate the operational state of the sensor arrangement (301; 401) and to control the active road-noise control module (108, 109) so that the active road-noise control module (108, 109) operates in the first mode of operation when the sensor arrangement (301; 401) is in a proper operational state and in the second mode of operation when a malfunction of the sensor arrangement (301; 401) has been detected, characterized in that the malfunction detection module (115; 205; 306) is further configured to compare the first sense signal with the second sense signal to evaluate the operational state of the sensor arrangement (301; 401). a sensor arrangement (301; 401) configured to generate a first sense signal representative of at least one of acceleration, motion and vibration that occurs at a first position on a vehicle body and a second sense signal representative of sound that occurs at a second position within the vehicle body; an active road-noise control module (108, 109) configured to provide a noise-reducing signal by processing the first sense signal and the second sense signal according to a first mode of operation or a second mode of operation; at least one loudspeaker (111; 114; 202) disposed at a third position within the vehicle body and configured to generate noise-reducing sound at the second position from the noise-reducing signal; and a malfunction detection module (115; 205; 306) configured to evaluate the operational state of the sensor arrangement (301; 401) and to control the active road-noise control module (108, 109) so that the active road-noise control module (108, 109) operates in the first mode of operation when the sensor arrangement (301; 401) is in a proper operational state and in the second mode of operation when a malfunction of the sensor arrangement (301; 401) has been detected, characterized in that the malfunction detection module (115; 205; 306) is further configured to compare the first sense signal with the second sense signal to evaluate the operational state of the sensor arrangement (301; 401).
Gas treatment system with at least one channel for channelling at least one gas flow and with at least injection lance introduced in the at least one channel to inject exclusively at least one vaporous and/or liquid additive component in the at least one gas flow, wherein the at least one injection lance comprises at least one nozzle unit to inject the at least one additive component into the at least one gas flow via at least one nozzle opening and at least one supply unit to supply the at least one additive component to the at least one nozzle unit, wherein at least one SCR catalyst is arranged downstream of the at least one injection lance in the flow direction of the at least one gas flow for the reaction of the additive component and at least one component of the at least one gas flow for the selective reduction of nitrogen oxides (NO x) in the at least one gas flow, and wherein at least one collar surrounding the at least one nozzle opening and extending in the injection direction of the additive component is provided, characterised in that the collar is formed to shield the nozzle opening from the gas flow flowing past the collar.
A labelling machine comprising: a supply spool support for supporting a spool of label carrying web, a labelling station arranged to remove labels from a label carrying web supported by the supply spool, a take up spool support for supporting a label take up spool to take up the web from which labels have been removed, and a first motive apparatus for transporting web from the supply spool support to the take up spool support via the labelling station, wherein the supply spool support, the labelling station and the take up spool support are mounted to a base plate, wherein the base plate includes: a first portion which supports the labelling station via a base of the labelling station such that the labelling station extends from the base plate in a first direction, and a second portion which supports one or more of the supply spool support, take-up spool support and first motive apparatus, wherein the maximum distance to which the second portion and any component supported by the second portion extend from the base of the labelling station in a second direction is greater than the maximum distance to which the first portion and any component supported by the first portion extend from the base of the labelling station in the second direction, the first and second directions being generally opposite; characterised in that a first wall separates the first portion and the second portion, and extends generally in the second direction. a supply spool support for supporting a spool of label carrying web, a labelling station arranged to remove labels from a label carrying web supported by the supply spool, a take up spool support for supporting a label take up spool to take up the web from which labels have been removed, and a first motive apparatus for transporting web from the supply spool support to the take up spool support via the labelling station, wherein the supply spool support, the labelling station and the take up spool support are mounted to a base plate, wherein the base plate includes: a first portion which supports the labelling station via a base of the labelling station such that the labelling station extends from the base plate in a first direction, and a second portion which supports one or more of the supply spool support, take-up spool support and first motive apparatus, a first portion which supports the labelling station via a base of the labelling station such that the labelling station extends from the base plate in a first direction, and a second portion which supports one or more of the supply spool support, take-up spool support and first motive apparatus, wherein the maximum distance to which the second portion and any component supported by the second portion extend from the base of the labelling station in a second direction is greater than the maximum distance to which the first portion and any component supported by the first portion extend from the base of the labelling station in the second direction, the first and second directions being generally opposite; characterised in that a first wall separates the first portion and the second portion, and extends generally in the second direction.
A chimeric polypeptide comprising: a) a recombinase, a transcription factor or nuclease; and b) a Xanthomonas derived or a Ralstonia derived transcription activator-like effector (TALE) protein, wherein the Xanthomonas derived TALE protein has an N-terminal domain comprising an amino acid sequence in the N- 1 hairpin as set forth in SEQ ID NO: 3 (VGKQWSGARAL) except for one or more mutations selected from: Q is Y, Q is S, Q is R, W is R, W is G, W is deleted, S is R, S is H, S is A, S is N, and S is T; and wherein the Ralstonia derived TALE protein has an N-terminal domain comprising an amino acid sequence in the N- 1 hairpin as set forth in SEQ ID NO: 8 (IVDIAR1QR2SGDLA) except for one or more mutations selected from: R 1 is K, Q is Y, Q is S, Q is R, R 2 is W, R 2 is G, R 2 is deleted, S is R, S is H, S is A, S is N, and S is T. a) a recombinase, a transcription factor or nuclease; and b) a Xanthomonas derived or a Ralstonia derived transcription activator-like effector (TALE) protein, wherein the Xanthomonas derived TALE protein has an N-terminal domain comprising an amino acid sequence in the N- 1 hairpin as set forth in SEQ ID NO: 3 (VGKQWSGARAL) except for one or more mutations selected from: Q is Y, Q is S, Q is R, W is R, W is G, W is deleted, S is R, S is H, S is A, S is N, and S is T; and wherein the Ralstonia derived TALE protein has an N-terminal domain comprising an amino acid sequence in the N- 1 hairpin as set forth in SEQ ID NO: 8 (IVDIAR1QR2SGDLA) except for one or more mutations selected from: R 1 is K, Q is Y, Q is S, Q is R, R 2 is W, R 2 is G, R 2 is deleted, S is R, S is H, S is A, S is N, and S is T. wherein the Xanthomonas derived TALE protein has an N-terminal domain comprising an amino acid sequence in the N- 1 hairpin as set forth in SEQ ID NO: 3 (VGKQWSGARAL) except for one or more mutations selected from: Q is Y, Q is S, Q is R, W is R, W is G, W is deleted, S is R, S is H, S is A, S is N, and S is T; and wherein the Ralstonia derived TALE protein has an N-terminal domain comprising an amino acid sequence in the N- 1 hairpin as set forth in SEQ ID NO: 8 (IVDIAR1QR2SGDLA) except for one or more mutations selected from: R 1 is K, Q is Y, Q is S, Q is R, R 2 is W, R 2 is G, R 2 is deleted, S is R, S is H, S is A, S is N, and S is T.