A method of forming a three-dimensional article, said method comprising: I) printing a first thermoplastic silicone composition with a 3D printer to form an at least partially solidified layer; II) printing a second thermoplastic silicone composition on the at least partially solidified layer with the 3D printer to form a subsequent at least partially solidified layer; and III) optionally, repeating step II) with independently selected thermoplastic silicone composition(s) for any additional layer(s) to form the 3D article; wherein the first and second thermoplastic silicone compositions are the same as or different from one another; (a) wherein the first and/or second thermoplastic silicone composition(s) comprise(s) a thermoplastic silicone polymer composition and wherein the thermoplastic silicone polymer composition comprises a silicone copolymer selected from a poly(dimethylsiloxane-co-diphenylsiloxane), a polysilphenylene, a poly(silphenylene-dimethylsiloxane), a poly(phenylmethylsiloxane-co-diphenylsiloxane), a silicone-polyurethane copolymer, a silicone-polyamide copolymer, a silicone-polyetherimide copolymer, a silicone-polysulfone copolymer, a silicone-polyester copolymer, a silicone-polyetherketone copolymer, a silicone-polyacrylate copolymer, a silicone-polyvinyl copolymer, a silicone-polyurea copolymer, a silicone-polyphenylene copolymer, a silicone-polysulfide copolymer, a silicone-polyether copolymer, a silicone-polyphosphazene copolymer, a silicone-polycarbohydrate copolymer or sugar siloxane, a silicone-polyolefin copolymer or silicone wax, a silicone-polypeptide copolymer, and a silicone-polycarborane copolymer; or (b) wherein the first and/or second thermoplastic silicone compositions comprises a silicone hot melt composition; or (c) wherein the first and/or second thermoplastic silicone compositions comprises a thermoplastic silicone vulcanizate composition. I) printing a first thermoplastic silicone composition with a 3D printer to form an at least partially solidified layer; II) printing a second thermoplastic silicone composition on the at least partially solidified layer with the 3D printer to form a subsequent at least partially solidified layer; and III) optionally, repeating step II) with independently selected thermoplastic silicone composition(s) for any additional layer(s) to form the 3D article; wherein the first and second thermoplastic silicone compositions are the same as or different from one another; (a) wherein the first and/or second thermoplastic silicone composition(s) comprise(s) a thermoplastic silicone polymer composition and wherein the thermoplastic silicone polymer composition comprises a silicone copolymer selected from a poly(dimethylsiloxane-co-diphenylsiloxane), a polysilphenylene, a poly(silphenylene-dimethylsiloxane), a poly(phenylmethylsiloxane-co-diphenylsiloxane), a silicone-polyurethane copolymer, a silicone-polyamide copolymer, a silicone-polyetherimide copolymer, a silicone-polysulfone copolymer, a silicone-polyester copolymer, a silicone-polyetherketone copolymer, a silicone-polyacrylate copolymer, a silicone-polyvinyl copolymer, a silicone-polyurea copolymer, a silicone-polyphenylene copolymer, a silicone-polysulfide copolymer, a silicone-polyether copolymer, a silicone-polyphosphazene copolymer, a silicone-polycarbohydrate copolymer or sugar siloxane, a silicone-polyolefin copolymer or silicone wax, a silicone-polypeptide copolymer, and a silicone-polycarborane copolymer; or (b) wherein the first and/or second thermoplastic silicone compositions comprises a silicone hot melt composition; or (c) wherein the first and/or second thermoplastic silicone compositions comprises a thermoplastic silicone vulcanizate composition. (a) wherein the first and/or second thermoplastic silicone composition(s) comprise(s) a thermoplastic silicone polymer composition and wherein the thermoplastic silicone polymer composition comprises a silicone copolymer selected from a poly(dimethylsiloxane-co-diphenylsiloxane), a polysilphenylene, a poly(silphenylene-dimethylsiloxane), a poly(phenylmethylsiloxane-co-diphenylsiloxane), a silicone-polyurethane copolymer, a silicone-polyamide copolymer, a silicone-polyetherimide copolymer, a silicone-polysulfone copolymer, a silicone-polyester copolymer, a silicone-polyetherketone copolymer, a silicone-polyacrylate copolymer, a silicone-polyvinyl copolymer, a silicone-polyurea copolymer, a silicone-polyphenylene copolymer, a silicone-polysulfide copolymer, a silicone-polyether copolymer, a silicone-polyphosphazene copolymer, a silicone-polycarbohydrate copolymer or sugar siloxane, a silicone-polyolefin copolymer or silicone wax, a silicone-polypeptide copolymer, and a silicone-polycarborane copolymer; or (b) wherein the first and/or second thermoplastic silicone compositions comprises a silicone hot melt composition; or (c) wherein the first and/or second thermoplastic silicone compositions comprises a thermoplastic silicone vulcanizate composition.