mhurhangee/ep-ind-claims huggingface dataset:
An interposer subassembly for an electronic system having at least one integrated circuit component, comprising: a flexible base layer, having a first surface and an opposing second surface; at least one active electronic circuit component comprising a thin film of semiconductor material, operatively integrated and embedded directly within said flexible base layer; at least one first patterned contact layer, provided on any one of said first surface and said second surface of said flexible base layer, and configured to operably interface with said at least one active electronic circuit component and the at least one IC component. a flexible base layer, having a first surface and an opposing second surface; at least one active electronic circuit component comprising a thin film of semiconductor material, operatively integrated and embedded directly within said flexible base layer; at least one first patterned contact layer, provided on any one of said first surface and said second surface of said flexible base layer, and configured to operably interface with said at least one active electronic circuit component and the at least one IC component.
Method of monitoring a zone of a metal structure in terms of its electrical resistance in order to detect possible defects in the structure, by periodically passing current through the zone in different directions while measuring and recording voltage drops between a number of contact points (C ij) arranged in rows and columns forming a matrix pattern, characterized in that the contact points in each adjacent two rows are mutually displaced in relation to one another so that each column of contact points is comprised by contact points in every second row of the matrix, thus forming unit areas (a ij) surrounded by four neighbouring contact points belonging to three different matrix rows,, and for each unit area(a ij) performing arithmetic addition of at least two measured values recorded during at least two measurements made with current passing in different directions, and by comparing values obtained by at least one similarly obtained value made earlier.
A desiccant container (10, 110) for an air dryer cartridge (12, 112) for a vehicle, especially utility vehicle, with at least one container cover (14a, 114a); with at least one container body for accommodating at least one desiccant; and with at least one pretension device (20, 120) for pretension, in a mounted state, the desiccant internally against the container body and/or the container cover (14a, 114a); wherein the container cover (14a, 114a) and the pretension device (20, 120), in a pre-mounted state, are formed as a common pre-mounted unit (11, 111), characterized in that the common pre-mounted unit (11, 111) comprises at least one locking device (13, 113) for holding, in the pre-mounted state, the pretension device (20, 120) in at least one compressed state.
A method for determining presence of cancer stem cells in a sample, preferably a biological sample of a human patient having or suspected of having a cancer, which method comprises measuring the levels of CD14 and CD44 in the sample, wherein an elevated level of both CD14 and CD44 is indicative of the presence of cancer stem cells in the sample.
Fill level measurement device having control and evaluation electronics having a signal generator for generating an AC voltage, a signal detector for detecting an AC voltage, reflected from an input of a resonant measuring probe, from the resonant measuring probe having the input, and a connecting element that electrically and mechanically connects the control and evaluation electronics to the measuring probe, characterized in that the connecting element has a first connecting line, which connects the signal generator to the input of the measuring probe, and a second connecting line, which connects the input of the measuring probe to the signal detector.
A cosmetic method of improving the appearance of a hyperpigmented spot comprising the step of identifying a plurality of hyperpigmented spots on a facial skin surface; applying a first composition comprising a safe and effective amount, preferably between 0.00008% and 1.25% by weight of the composition, of an Laminaria Saccharina extract to the hyperpigmented spot on the facial skin surface, wherein the composition is applied for a period of time sufficient for the Laminaria Saccharina extract to improve the appearance of the hyperpigmented spots.
A compound of formula I wherein X denotes COOH or a salt thereof, COOR 1, wherein R 1 is optionally substituted C 1-4 alkyl, CONR 2 R 3, wherein R 2 and R 3 independently of each other are H or C 1-5 alkyl, optionally comprising one or more heteroatoms from O, S and N, and/or optionally substituted, or CON(R 2)-CH(R 4)-R 5, wherein R 2 is as defined above, R 4 is a group normally occurring in the α position of α-amino acids,and R 5 is COOH or a salt thereof, COOR 1, wherein R 1 is as defined above; or CONR 2 R 3 wherein R 2 and R 3 are as defined above, Y and Y' both are H, or together denote =O, Z is O, NR 2 or N-CH(R 4)-R 5, wherein R 2, R 4 and R 5 are as defined above, n is 1 or 2, m is a number from 0 to 4, and R is H, or a saturated or unsaturated chain having 1 to 8 carbon atoms, optionally substituted by a 5- or 6 membered non-aromatic ring, having one or more heteroatoms selected from O, S and N, or by aryl, alkyl or cycloalkyl, optionally comprising one or more heteroatoms selected from O, S and N, and/or one or morefold substituted by heteroatoms selected from O, S and N, halogen Cl, Br, I and F and/or azido N 3. X denotes COOH or a salt thereof, COOR 1, wherein R 1 is optionally substituted C 1-4 alkyl, CONR 2 R 3, wherein R 2 and R 3 independently of each other are H or C 1-5 alkyl, optionally comprising one or more heteroatoms from O, S and N, and/or optionally substituted, or CON(R 2)-CH(R 4)-R 5, wherein R 2 is as defined above, R 4 is a group normally occurring in the α position of α-amino acids,and R 5 is COOH or a salt thereof, COOR 1, wherein R 1 is as defined above; or CONR 2 R 3 wherein R 2 and R 3 are as defined above, Y and Y' both are H, or together denote =O, Z is O, NR 2 or N-CH(R 4)-R 5, wherein R 2, R 4 and R 5 are as defined above, n is 1 or 2, m is a number from 0 to 4, and R is H, or a saturated or unsaturated chain having 1 to 8 carbon atoms, optionally substituted by a 5- or 6 membered non-aromatic ring, having one or more heteroatoms selected from O, S and N, or by aryl, alkyl or cycloalkyl, optionally comprising one or more heteroatoms selected from O, S and N, and/or one or morefold substituted by heteroatoms selected from O, S and N, halogen Cl, Br, I and F and/or azido N 3.
A low refractive layer satisfying the following formula 1: 0.5 ≥ Δ b * = b * 1 − b * 0 in the formula 1, b* 0 is a b* value in a L*a*b* color coordinate system as defined by the International Commission on Illumination as to the low refractive layer; and b* 1 is a b* value in a L*a*b* color coordinate system as measured in the same manner as a method for measuring b* 0 as to the film prepared by immersing the low refractive layer for 2 minutes in 10 wt% sodium hydroxide aqueous solution heated to 30°C, washing the immersed layer with water, wiping off moisture, followed by immersing the wiped layer for 30 seconds in 10 wt% sodium hydroxide aqueous solution heated to 55°C, washing it with water and wiping off moisture, wherein the low refractive layer is a layer exhibiting a refractive index of 1.2 to 1.6, and wherein the low refractive layer includes a photocured product obtained by photo-curing a photocurable coating composition comprising a photopolymerizable compound, a fluorine-based compound containing -O-CF 2 CF 2 -O-CF 3, and a polysilsesquioxane substituted with at least one reactive functional group. b* 0 is a b* value in a L*a*b* color coordinate system as defined by the International Commission on Illumination as to the low refractive layer; and b* 1 is a b* value in a L*a*b* color coordinate system as measured in the same manner as a method for measuring b* 0 as to the film prepared by immersing the low refractive layer for 2 minutes in 10 wt% sodium hydroxide aqueous solution heated to 30°C, washing the immersed layer with water, wiping off moisture, followed by immersing the wiped layer for 30 seconds in 10 wt% sodium hydroxide aqueous solution heated to 55°C, washing it with water and wiping off moisture, wherein the low refractive layer is a layer exhibiting a refractive index of 1.2 to 1.6, and wherein the low refractive layer includes a photocured product obtained by photo-curing a photocurable coating composition comprising a photopolymerizable compound, a fluorine-based compound containing -O-CF 2 CF 2 -O-CF 3, and a polysilsesquioxane substituted with at least one reactive functional group.
A chimeric antigen receptor polypeptide, the CAR contains at least the following domains starting from the N-terminus to the C-terminus: i) an anti-CD30 single chain antibody domainHRS3 scFv peptide of SEQ ID No. 2, ii) optionally a spacer domain; iii) a transmembrane domain; and iv) a cytoplasmic domain comprising: - a cytoplasmatic CD28 signalling domain having SEQ ID NO:6 and lacking the Ick binding motif, and - a CD3-zeta or an FcepsilonRlgamma signalling domain. i) an anti-CD30 single chain antibody domainHRS3 scFv peptide of SEQ ID No. 2, ii) optionally a spacer domain; iii) a transmembrane domain; and iv) a cytoplasmic domain comprising: - a cytoplasmatic CD28 signalling domain having SEQ ID NO:6 and lacking the Ick binding motif, and - a CD3-zeta or an FcepsilonRlgamma signalling domain. - a cytoplasmatic CD28 signalling domain having SEQ ID NO:6 and lacking the Ick binding motif, and - a CD3-zeta or an FcepsilonRlgamma signalling domain.
Fine-dust collection member for a bagless vacuum cleaner comprising a fine-dust filter received by the fine-dust collection member, characterised in that the fine-dust collection member comprises a sedimentation vessel for fine dust below a position of the fine-dust filter, the sedimentation vessel being arranged in a flow-calmed zone of the fine-dust collection member.
A security inspection system for persons, comprising: a passageway which provides an inspection space isolated or partially isolated from an ambient environment, wherein a plurality of sub-passageways allowing persons to be inspected to pass is provided in the inspection space, and each of the sub-passageways is provided with at least one millimeter wave imaging device for millimeter wave imaging of persons being inspected; and an ion mobility spectrometer for ionizing particles of substance or gases that are given off or volatilized from the inspected persons within at least one of the sub-passageways into the air in the passageway and then measuring a mobility rate thereof under the action of the electric field to effect identification of substances, characterized in that an isolation means is provided at both ends of the passageway to keep the entrance and exit of the passageway at least partly isolated from the ambient environment.
A medical fluid waste container assembly, comprising: a container; a base forming a bottom for the container, the base having an interior surface at least partially defining a drain opening; a lid assembly providing selective access to an interior of the container; and characterised in that the interior surface of the base has an outer perimeter at least partially defined by a perimeter wall and an inner perimeter at least partially defined by a wall, where said wall at least partially defining the inner perimeter extends from the interior surface to a base surface, wherein the interior surface of the base extends along a ramped path, the interior surface following the path to direct collected waste toward the drain opening and solids of the medical waste away from the base surface, the path declining toward the drain opening in the shape of a ramped crescent, the interior surface including a non-linear surface. a container; a base forming a bottom for the container, the base having an interior surface at least partially defining a drain opening; a lid assembly providing selective access to an interior of the container; and characterised in that the interior surface of the base has an outer perimeter at least partially defined by a perimeter wall and an inner perimeter at least partially defined by a wall, where said wall at least partially defining the inner perimeter extends from the interior surface to a base surface, wherein the interior surface of the base extends along a ramped path, the interior surface following the path to direct collected waste toward the drain opening and solids of the medical waste away from the base surface, the path declining toward the drain opening in the shape of a ramped crescent, the interior surface including a non-linear surface.
A computer-implemented method for converting an input audio signal into one or more haptic effects, the computer-implemented method comprising: receiving the input audio signal (910, 1030); shifting a frequency content of the input audio signal (910, 1030) to a haptically perceptible range less than 1 kHz to form a frequency-shifted signal; segmenting the frequency-shifted signal into a plurality of waveforms (220, 911, 920, 930), wherein each waveform (220, 911, 920, 930) comprises at least a portion of the frequency-shifted signal; combining each waveform (220, 911, 920, 930) with an envelope (210, 940) to generate a grain (200, 480, 610, 620, 810, 950, 1010, 1220, 1230, 1240), wherein a plurality of grains is generated, wherein each grain (200, 480, 610, 620, 810, 950, 1010, 1220, 1230, 1240) of the plurality of grains comprises an amplitude parameter, a waveform parameter, an envelope parameter, and a duration parameter, wherein each grain (200, 480, 610, 620, 810, 950, 1010, 1220, 1230, 1240) of the plurality of grains is mapped to a corresponding position on a touchscreen, and wherein generation of at least one of the plurality of grains is triggered according to a sensor signal comprising a signal value indicating a position of a touchscreen input at the corresponding position on the touchscreen; combining the plurality of grains to generate a cloud, wherein the cloud comprises a representation of the plurality of grains; and generating the one or more haptic effects based on the cloud. receiving the input audio signal (910, 1030); shifting a frequency content of the input audio signal (910, 1030) to a haptically perceptible range less than 1 kHz to form a frequency-shifted signal; segmenting the frequency-shifted signal into a plurality of waveforms (220, 911, 920, 930), wherein each waveform (220, 911, 920, 930) comprises at least a portion of the frequency-shifted signal; combining each waveform (220, 911, 920, 930) with an envelope (210, 940) to generate a grain (200, 480, 610, 620, 810, 950, 1010, 1220, 1230, 1240), wherein a plurality of grains is generated, wherein each grain (200, 480, 610, 620, 810, 950, 1010, 1220, 1230, 1240) of the plurality of grains comprises an amplitude parameter, a waveform parameter, an envelope parameter, and a duration parameter, wherein each grain (200, 480, 610, 620, 810, 950, 1010, 1220, 1230, 1240) of the plurality of grains is mapped to a corresponding position on a touchscreen, and wherein generation of at least one of the plurality of grains is triggered according to a sensor signal comprising a signal value indicating a position of a touchscreen input at the corresponding position on the touchscreen; combining the plurality of grains to generate a cloud, wherein the cloud comprises a representation of the plurality of grains; and generating the one or more haptic effects based on the cloud.
A chimeric clotting factor which comprises i) a clotting factor comprising a FVII polypeptide ii) a targeting moiety which binds to platelets, and iii) a scaffold moiety comprising an FcRn binding moiety, wherein the clotting factor is linked to the scaffold moiety directly or by a first linker, and wherein the targeting moiety is linked to the scaffold moiety directly or by a second linker, and wherein the scaffold moiety is a dimeric Fc region comprising a first Fc moiety, F1, and a second Fc moiety, F2. i) a clotting factor comprising a FVII polypeptide ii) a targeting moiety which binds to platelets, and iii) a scaffold moiety comprising an FcRn binding moiety,
Air intake device for an internal combustion engine, comprising an air filter device for cleaning the intake air, a choke device for changing the amount of intake air, a primary suction pipe arrangement which connects the choke device and an internal combustion engine in such a manner as to convey an airflow, and a secondary suction pipe arrangement (10; 110; 210) which connects the air filter device and the choke device in such a manner as to convey an airflow, it being possible to change at least one flow variable which influences the airflow behaviour of the air intake device, in particular a flow geometry, most preferably the flow length and/or the flow cross section and/or the flow course, of at least one suction pipe arrangement (8, 10; 110; 210), it being possible to selectively change at least one flow variable of the secondary suction pipe arrangement (10; 110; 210), the secondary suction pipe arrangement (10; 110; 210) further having precisely two different flow paths (20, 22; 120, 122; 260) through itself and a flow guiding means (24; 124; 224) for guiding an airflow through at least one of these flow paths (20, 22; 120, 122; 260), the flow guiding means (24; 124) having a partition, in particular a pivotable flap (26; 126), which is movable into a plurality of different flow guiding positions, characterised in that the flow guiding means (24; 124) is more precisely designed to selectively guide an airflow through one of the two flow paths (20, 22; 120, 122) and preferably is additionally designed to selectively guide an airflow through both flow paths (20, 22; 120, 122) at the same time.
An in situ method for determining the binding site of a chromatin-associated factor of interest to DNA sequences in a cell or nucleus, comprising: contacting a permeabilized cell or nucleus with a first specific binding agent that specifically binds the chromatin-associated factor interest wherein the first specific binding agent is coupled to a plurality of transposomes, each of the plurality of transposomes comprising: at least one transposase; and a transposon comprising: a first DNA molecule comprising a first transposase recognition site; and a second DNA molecule comprising a second transposase recognition site; activating the transposase, thereby excising and tagging the sequence of DNA bound to the chromatin-associated factor of interest with the DNA tag, wherein the at least one transposase integrates the first and second DNA molecules into chromatin DNA, thereby cleaving and tagging chromatin DNA with the first and second DNA molecules; isolating the excised DNA; and determining the sequence of the excised DNA, thereby mapping binding of a chromatin-associated factor of interest to one or more sequences of DNA in the cell or nucleus. contacting a permeabilized cell or nucleus with a first specific binding agent that specifically binds the chromatin-associated factor interest wherein the first specific binding agent is coupled to a plurality of transposomes, each of the plurality of transposomes comprising: at least one transposase; and a transposon comprising: a first DNA molecule comprising a first transposase recognition site; and a second DNA molecule comprising a second transposase recognition site; at least one transposase; and a transposon comprising: a first DNA molecule comprising a first transposase recognition site; and a second DNA molecule comprising a second transposase recognition site; a first DNA molecule comprising a first transposase recognition site; and a second DNA molecule comprising a second transposase recognition site; activating the transposase, thereby excising and tagging the sequence of DNA bound to the chromatin-associated factor of interest with the DNA tag, wherein the at least one transposase integrates the first and second DNA molecules into chromatin DNA, thereby cleaving and tagging chromatin DNA with the first and second DNA molecules; isolating the excised DNA; and determining the sequence of the excised DNA, thereby mapping binding of a chromatin-associated factor of interest to one or more sequences of DNA in the cell or nucleus.
Thermal cycler comprising: - a housing, the housing accommodating a thermal block having a plurality of sample wells, each for receiving a test sample in a sample vessel, electric heater means for heating the thermal block, a power supply and an electronic control for controlling the electric heater means, - a temperature analysis and verification unit for analyzing and verifying a thermal performance of the thermal block, i.e. that the temperatures achieved in the samples wells are according to specification, - wherein the temperature analysis and verification unit comprises a temperature probe plate having a plurality of temperature probes for measuring the temperature within selected sample wells, characterized in that the temperature analysis and verification unit is integrated into the housing and is connected to the power supply and to the electronic control by means of an internal interface and in that an electric connection between the temperature probe plate and the interface can be disconnected for removal of the temperature probe plate from the thermal cycler for external calibration. - a housing, the housing accommodating a thermal block having a plurality of sample wells, each for receiving a test sample in a sample vessel, electric heater means for heating the thermal block, a power supply and an electronic control for controlling the electric heater means, - a temperature analysis and verification unit for analyzing and verifying a thermal performance of the thermal block, i.e. that the temperatures achieved in the samples wells are according to specification, - wherein the temperature analysis and verification unit comprises a temperature probe plate having a plurality of temperature probes for measuring the temperature within selected sample wells,