A pneumatic tire comprising: a tread portion having an outboard tread edge (To) to be positioned away from the center of a vehicle body and an inboard tread edge (Ti) to be positioned close to the center of the vehicle body, the tread portion provided with main grooves extending continuously in the tire circumferential direction, and comprising an inboard shoulder land portion defined between the inboard tread edge (Ti) and an inboard shoulder main groove which is the main groove on the most inboard tread edge side, the inboard shoulder land portion provided with inboard semi-open shoulder lateral grooves and inboard shoulder sipes disposed between the inboard semi-open shoulder lateral grooves and having a width of not more than 1.0 mm, wherein the inboard semi-open shoulder lateral grooves extend axially inwardly from the inboard tread edge (Ti) and terminate without reaching the inboard shoulder main groove so as to have axially inner ends within the inboard shoulder land portion, and the inboard shoulder sipes extend axially inwardly from the inboard tread edge (Ti) and terminate without reaching the inboard shoulder main groove so as to have axially inner ends within the inboard shoulder land portion, wherein the inboard shoulder main groove has a groove width in a range from 3% to 7% of the tread width between the outboard tread edge (To) and the inboard tread edge (Ti), wherein the main grooves include an outboard shoulder main groove which is the main groove on the most outboad tread edge side characterized in that the groove width of the inboard shoulder main groove is larger than a groove width of the outboard shoulder main groove. a tread portion having an outboard tread edge (To) to be positioned away from the center of a vehicle body and an inboard tread edge (Ti) to be positioned close to the center of the vehicle body, the tread portion provided with main grooves extending continuously in the tire circumferential direction, and comprising an inboard shoulder land portion defined between the inboard tread edge (Ti) and an inboard shoulder main groove which is the main groove on the most inboard tread edge side, the inboard shoulder land portion provided with inboard semi-open shoulder lateral grooves and inboard shoulder sipes disposed between the inboard semi-open shoulder lateral grooves and having a width of not more than 1.0 mm, wherein the inboard semi-open shoulder lateral grooves extend axially inwardly from the inboard tread edge (Ti) and terminate without reaching the inboard shoulder main groove so as to have axially inner ends within the inboard shoulder land portion, and the inboard shoulder sipes extend axially inwardly from the inboard tread edge (Ti) and terminate without reaching the inboard shoulder main groove so as to have axially inner ends within the inboard shoulder land portion, wherein the inboard shoulder main groove has a groove width in a range from 3% to 7% of the tread width between the outboard tread edge (To) and the inboard tread edge (Ti), wherein the main grooves include an outboard shoulder main groove which is the main groove on the most outboad tread edge side characterized in that the groove width of the inboard shoulder main groove is larger than a groove width of the outboard shoulder main groove.