mhurhangee/ep-ind-claims huggingface dataset:
A phenalkamine represented by the structure of formula: wherein n = 0, 2, 4 or 6; wherein R = H, C 1 -C 10 alkyl, Ph or a C 5 -C 6 cycloaliphatic group; and wherein each of A, B, C, D and E = H or a group with the structure of formula wherein n = 0, 2, 4 or 6, wherein, independently, R = H, C 1 -C 10 alkyl, Ph, or a C 5 -C 6 cycloaliphatic group, provided that at least two substituents selected from A, B, C, D, and E are H, and bonding occurs via the asterisk. wherein n = 0, 2, 4 or 6; wherein R = H, C 1 -C 10 alkyl, Ph or a C 5 -C 6 cycloaliphatic group; and wherein each of A, B, C, D and E = H or a group with the structure of formula wherein n = 0, 2, 4 or 6, wherein, independently, R = H, C 1 -C 10 alkyl, Ph, or a C 5 -C 6 cycloaliphatic group, provided that at least two substituents selected from A, B, C, D, and E are H, and bonding occurs via the asterisk.
In vitro Method for the identification of agents that have a potential effect against chronic inflammatory conditions with the following steps: a.) stimulating cells expressing GPRC6A and cells expressing CaSR with at least one TLR-ligandand calcium, b.) selecting an agent that blocks the stimulation of the cells expressing GPRC6A and has no or an reduced blocking effect on the stimulation of the cells expressing CaSR, whereas reduced blocking effect means that the blocking effect on the stimulation of the cells expressing CaSR is lower than on the cells expressing GPRC6A. a.) stimulating cells expressing GPRC6A and cells expressing CaSR with at least one TLR-ligandand calcium, b.) selecting an agent that blocks the stimulation of the cells expressing GPRC6A and has no or an reduced blocking effect on the stimulation of the cells expressing CaSR, whereas reduced blocking effect means that the blocking effect on the stimulation of the cells expressing CaSR is lower than on the cells expressing GPRC6A.
A control support apparatus, comprising: an equipment abnormality estimation section for estimating an abnormality of equipment based on measurement data by measuring the equipment; a simulation section for simulating a future state of the equipment when controlling the equipment by each of a plurality of candidate control methods according to an abnormality estimation result of the equipment; and a control instruction section for instructing a control apparatus of the equipment to control the equipment by a control method selected based on a simulation result of the simulation section from the plurality of candidate control methods; characterized in that the simulation section is configured to perform a simulation for a first plurality of candidate control methods and a second plurality of candidate control methods; and the control instruction section is configured to instruct: the control apparatus to control the equipment by a selected control method from the first plurality of candidate control methods, before a completion of a simulation for the second plurality of candidate control methods, in response to a completion of a simulation for the first plurality of candidate control methods; and the control apparatus to control the equipment by a selected control method from candidate control methods including the second plurality of candidate control methods, in response to a completion of a simulation for the second plurality of candidate control methods. an equipment abnormality estimation section for estimating an abnormality of equipment based on measurement data by measuring the equipment; a simulation section for simulating a future state of the equipment when controlling the equipment by each of a plurality of candidate control methods according to an abnormality estimation result of the equipment; and a control instruction section for instructing a control apparatus of the equipment to control the equipment by a control method selected based on a simulation result of the simulation section from the plurality of candidate control methods; characterized in that the simulation section is configured to perform a simulation for a first plurality of candidate control methods and a second plurality of candidate control methods; and the control instruction section is configured to instruct: the control apparatus to control the equipment by a selected control method from the first plurality of candidate control methods, before a completion of a simulation for the second plurality of candidate control methods, in response to a completion of a simulation for the first plurality of candidate control methods; and the control apparatus to control the equipment by a selected control method from candidate control methods including the second plurality of candidate control methods, in response to a completion of a simulation for the second plurality of candidate control methods.
A compound selected from compounds of Formula ( Ia) and pharmaceutically acceptable salts, solvates, hydrates, and N -oxides thereof: wherein: Y is selected from: -CH 2 -, -O-, and -S-; Ring A is pyridinediyl or pyrazine-2,6-diyl; R 1 is H or C 1 -C 6 alkyl; R 2 is H or halogen; R 3 is aryl or heteroaryl, wherein each ring is optionally substituted with one or more groups selected independently from: C 1 -C 6 acyl, C 1 -C 6 acyloxy, C 1 -C 6 alkoxy, C 1 -C 6 alkylcarboxamide, C 1 -C 6 alkyl, cyano, C 1 -C 6 haloalkoxy, C 1 -C 6 haloalkyl, halogen, hydroxyl, and hydroxy-C 1 -C 6 -alkyl; and said C 1 -C 6 alkyl is optionally substituted with one or more groups selected independently from: C 1 -C 6 alkylamino, C 2 -C 6 dialkylamino, and oxo; R 4 is H; and R 5 is selected from: H, C 1 -C 6 alkyl, heteroaryl, heteroaryl-C 1 -C 6 alkyl, heterocyclyl, heterocyclyl-C 1 -C 6 alkyl, and hydroxy-C 1 -C 6 -alkyl; and each group is optionally substituted with one or more groups selected independently from: C 1 -C 6 alkoxy, C 1 -C 6 alkylcarboxamide, C 1 -C 6 alkyl, cyano, C 1 -C 6 alkylamino, C 2 -C 6 dialkylamino, C 1 -C 6 haloalkyl, halogen, hydroxyl, hydroxy-C 1 -C 6 -alkoxy, hydroxy-C 1 -C 6 -alkyl, and oxo; wherein aryl refers to a ring system containing 6 to 10 carbon atoms that may contain a single ring or two fused rings, wherein at least one ring is aromatic; and heteroaryl refers to a ring system containing 5 to 10 ring atoms, that may contain a single ring, two fused rings or three fused rings, wherein at least one ring is aromatic and at least one ring atom is a heteroatom. Y is selected from: -CH 2 -, -O-, and -S-; Ring A is pyridinediyl or pyrazine-2,6-diyl; R 1 is H or C 1 -C 6 alkyl; R 2 is H or halogen; R 3 is aryl or heteroaryl, wherein each ring is optionally substituted with one or more groups selected independently from: C 1 -C 6 acyl, C 1 -C 6 acyloxy, C 1 -C 6 alkoxy, C 1 -C 6 alkylcarboxamide, C 1 -C 6 alkyl, cyano, C 1 -C 6 haloalkoxy, C 1 -C 6 haloalkyl, halogen, hydroxyl, and hydroxy-C 1 -C 6 -alkyl; and said C 1 -C 6 alkyl is optionally substituted with one or more groups selected independently from: C 1 -C 6 alkylamino, C 2 -C 6 dialkylamino, and oxo; R 4 is H; and R 5 is selected from: H, C 1 -C 6 alkyl, heteroaryl, heteroaryl-C 1 -C 6 alkyl, heterocyclyl, heterocyclyl-C 1 -C 6 alkyl, and hydroxy-C 1 -C 6 -alkyl; and each group is optionally substituted with one or more groups selected independently from: C 1 -C 6 alkoxy, C 1 -C 6 alkylcarboxamide, C 1 -C 6 alkyl, cyano, C 1 -C 6 alkylamino, C 2 -C 6 dialkylamino, C 1 -C 6 haloalkyl, halogen, hydroxyl, hydroxy-C 1 -C 6 -alkoxy, hydroxy-C 1 -C 6 -alkyl, and oxo; wherein aryl refers to a ring system containing 6 to 10 carbon atoms that may contain a single ring or two fused rings, wherein at least one ring is aromatic; and heteroaryl refers to a ring system containing 5 to 10 ring atoms, that may contain a single ring, two fused rings or three fused rings, wherein at least one ring is aromatic and at least one ring atom is a heteroatom.
A method for dehydrogenating a hydrogen carrier medium, comprising the method steps of - providing -- a metal-containing catalyst material, -- an at least partially loaded hydrogen carrier medium, -- a metal-free reaction accelerator substance, - transferring hydrogen from the hydrogen carrier medium to the reaction accelerator substance by means of the metal-containing catalyst material, - releasing hydrogen gas from the reaction accelerator substance by means of the metal-containing catalyst material, wherein the reaction accelerator substance has at least one functional group which contains oxygen and/or nitrogen. - providing -- a metal-containing catalyst material, -- an at least partially loaded hydrogen carrier medium, -- a metal-free reaction accelerator substance, -- a metal-containing catalyst material, -- an at least partially loaded hydrogen carrier medium, -- a metal-free reaction accelerator substance, - transferring hydrogen from the hydrogen carrier medium to the reaction accelerator substance by means of the metal-containing catalyst material, - releasing hydrogen gas from the reaction accelerator substance by means of the metal-containing catalyst material,
Cooling lubricant nozzle holder for a grinding machine, wherein the cooling lubricant nozzle holder comprises a middle shank and two lateral shanks (130, 140) arranged on the middle shank movably in relation to the middle shank, and wherein the cooling lubricant nozzle holder comprises at least two cooling lubricant nozzles (110, 120), at least one of which is arranged on each of the lateral shanks (130, 140), wherein each of the lateral shanks (130, 140) are movably mounted in relation to the middle shank such that each cooling lubricant nozzle (110, 120) which is arranged on one of the respective lateral shanks (130, 140) moves together with the lateral shank (130, 140) on a section of a circular path when the respective lateral shank (130, 140) moves, characterized in that the lateral shanks (130, 140) are arranged offset to each other in relation to the middle axis of the circular path on which the cooling lubricant nozzles (110, 120) move, together with the lateral shank (130, 140), when the respective lateral shank (130, 140) moves. wherein each of the lateral shanks (130, 140) are movably mounted in relation to the middle shank such that each cooling lubricant nozzle (110, 120) which is arranged on one of the respective lateral shanks (130, 140) moves together with the lateral shank (130, 140) on a section of a circular path when the respective lateral shank (130, 140) moves, characterized in that the lateral shanks (130, 140) are arranged offset to each other in relation to the middle axis of the circular path on which the cooling lubricant nozzles (110, 120) move, together with the lateral shank (130, 140), when the respective lateral shank (130, 140) moves.
A sheet-like composite, comprising as layers of a layer sequence: a) an outer polymer layer, b) a carrying layer following the outer polymer layer, c) a barrier layer following the carrying layer, d) an adhesion-promoting layer following the barrier layer, and e) an inner polymer layer following the adhesion-promoting layer; wherein the adhesion-promoting layer comprises an outer surface of the adhesion-promoting layer and an inner surface of the adhesion-promoting layer; wherein the outer surface of the adhesion-promoting layer i) is adjacent to the barrier layer, and ii) is characterised by a first C=O group absorption maximum; wherein the inner surface of the adhesion-promoting layer A) is adjacent to the inner polymer layer, B) is characterised by a second C=O group absorption maximum, and C) has a first distance to the outer surface of the adhesion-promoting layer; wherein the first C=O group absorption maximum is higher than the second C=O group absorption maximum. a) an outer polymer layer, b) a carrying layer following the outer polymer layer, c) a barrier layer following the carrying layer, d) an adhesion-promoting layer following the barrier layer, and e) an inner polymer layer following the adhesion-promoting layer; wherein the adhesion-promoting layer comprises an outer surface of the adhesion-promoting layer and an inner surface of the adhesion-promoting layer; wherein the outer surface of the adhesion-promoting layer i) is adjacent to the barrier layer, and ii) is characterised by a first C=O group absorption maximum; i) is adjacent to the barrier layer, and ii) is characterised by a first C=O group absorption maximum; A) is adjacent to the inner polymer layer, B) is characterised by a second C=O group absorption maximum, and C) has a first distance to the outer surface of the adhesion-promoting layer;
Process for producing a rod, by a) extruding a plastics profile made of a first plastics moulding composition which forms the outermost layer and which is composed of at least 50% by weight of a semicrystalline thermoplastic, b) within the calibrator, a second plastics moulding composition is inserted into the freshly extruded profile and c) calibrating, drawing off and cooling the newly formed rod, characterized in that the first plastics moulding composition has the following properties: - crystallite melting point T m in accordance with ISO 11357 of at least 170°C, - crystallization temperature T k in accordance with ISO 11357 of at most 70 K below T m and - enthalpy of fusion AH in accordance with ISO 11357 of at least 20 J/g. a) extruding a plastics profile made of a first plastics moulding composition which forms the outermost layer and which is composed of at least 50% by weight of a semicrystalline thermoplastic, b) within the calibrator, a second plastics moulding composition is inserted into the freshly extruded profile and c) calibrating, drawing off and cooling the newly formed rod, - crystallite melting point T m in accordance with ISO 11357 of at least 170°C, - crystallization temperature T k in accordance with ISO 11357 of at most 70 K below T m and - enthalpy of fusion AH in accordance with ISO 11357 of at least 20 J/g.
Battery for powering an electric motor of a motor vehicle, the battery comprising electrochemical accumulators included in an adiabatic enclosure and included in an air-tight and water-tight enclosure, in which battery the tight enclosure encompasses the adiabatic enclosure and has a volume external to the adiabatic enclosure and that benefits from heat exchanges with the outside, the battery comprising a valve selectively establishing a flow of a heat transfer fluid between the adiabatic enclosure and said volume, characterized in that the tight enclosure is configured to be elastically deformed upon a variation of pressure inside the latter.
Pneumatic vehicle tyre, in particular for use in winter driving conditions, comprising a tread having positive profiles, for example profile blocks or tread strips, which are separated from one another by grooves running around in the circumferential direction, by transverse grooves and the like, which positive profiles are each provided with a multiplicity of narrow sipes, which extend at least substantially parallel to one another and at least substantially in the transverse direction of the tread and the mutually opposite sipe walls of which have projections (6, 7) and depressions (16, 17) that correspond to one another, having flattened sides oriented in the radial direction and substantially perpendicular to the sipe wall and having flattened sides oriented substantially parallel to the upper surface of the positive profile, characterized in that, overall, the projections (6, 7) are rounded raised areas, which are each surrounded by wall regions which remain unstructured, wherein projections are arranged at individual locations in the radially outer region of one sipe wall, each of said projections having a single flattened side, oriented in the radial direction and substantially perpendicular to the sipe wall, forming a support surface, and wherein projections are arranged at individual locations in the radially inner region of the sipe wall, each of said projections having a flattened side, oriented substantially parallel to the upper surface of the positive profile, forming a support surface.
A method of making a functionally graded metal matrix composite product comprising the steps of: - providing a molten metal containing particulate matter to a pair of advancing casting surfaces (R 1, R 2); - solidifying the molten metal while advancing the molten metal between the advancing casting surfaces (R 1, R 2) to form a product comprising a first solid outer layer, a second solid outer layer, and a semi-solid central layer therebetween, wherein the semi-solid central layer has a particulate matter concentration greater than particulate matter concentrations of the first or second solid outer layers (6, 8); - solidifying the semi-solid central layer to form a solid metal product comprised of the outer layers (6, 8) and the solidified central layer after-the semi-solid central layer passes a location of minimum distance between the casting surfaces (R 1, R 2); and - withdrawing the solid metal product from between the casting surfaces (R 1, R 2); the step of advancing the molten metal comprises advancing the molten metal mixture between the casting surfaces (R 1, R 2) at a speed ranging from 0.254 m/s (= 50 feet/minute) to 1.524 m/s (= 300 feet/minute) characterized in that the first and second solid outer layers (6, 8) have a combined thickness (T 2 + T 3) ranging from 60 to 90 % of the thickness of the solid metal product, wherein the thickness (T 1) of the solidified central layer is 10 to 40% of the thickness of the solid metal product; during the step of advancing the molten material particulate matter having a size of 30 microns or greater is moved into the semi-solid central layer; and that the particulate matter is selected from the group consisting of Aluminum Oxide, Boron Carbide, silicon Carbide, Boron Nitride, and any non-metallic material. - providing a molten metal containing particulate matter to a pair of advancing casting surfaces (R 1, R 2); - solidifying the molten metal while advancing the molten metal between the advancing casting surfaces (R 1, R 2) to form a product comprising a first solid outer layer, a second solid outer layer, and a semi-solid central layer therebetween, wherein the semi-solid central layer has a particulate matter concentration greater than particulate matter concentrations of the first or second solid outer layers (6, 8); - solidifying the semi-solid central layer to form a solid metal product comprised of the outer layers (6, 8) and the solidified central layer after-the semi-solid central layer passes a location of minimum distance between the casting surfaces (R 1, R 2); and - withdrawing the solid metal product from between the casting surfaces (R 1, R 2);
A powder pulverization method for pulverizing powder by causing high-pressure air to collide with powder introduced into a hermetically sealed pulverization container, and leading pulverized powder out from the pulverization container, characterized in that the method comprising performing the pulverization of powder while injecting air from a lined inner surface (60A, 60B) of the pulverization container.
A method for generating a target path for an autonomous vehicle, in which a controller for generating a target path that can be tracked by a host vehicle, that does not deviate from a road, and that involves no contact with an obstacle is provided, the method for generating a target path for an autonomous vehicle comprising: acquiring travel path boundaries of a road in the host vehicle surroundings determining a presence or absence of an occupant; generating a first target path upon determining that the occupant is present (S13, S15); generating a second target path upon determining no occupant is present (S14, S15); and a difference in target path is imparted between the first target path and the second target path; characterized in that the first target path and the second target path are each determined based on a path curvature function and a margin function with respect to the travel path boundaries; the first target path is determined by placing a greater weight on the path curvature function than the margin function with respect to the travel path boundaries; and the second target path is determined by placing a greater weight on the margin function with respect to the travel path boundaries than the path curvature function. acquiring travel path boundaries of a road in the host vehicle surroundings determining a presence or absence of an occupant; generating a first target path upon determining that the occupant is present (S13, S15); generating a second target path upon determining no occupant is present (S14, S15); and a difference in target path is imparted between the first target path and the second target path; characterized in that the first target path and the second target path are each determined based on a path curvature function and a margin function with respect to the travel path boundaries; the first target path is determined by placing a greater weight on the path curvature function than the margin function with respect to the travel path boundaries; and the second target path is determined by placing a greater weight on the margin function with respect to the travel path boundaries than the path curvature function.
A battery module comprising: two or more stacked battery cells which can be charged and discharged; and cartridges for fixing the respective battery cells to form a battery cell stack structure, wherein each of the cartridges is provided with a cooling plate having one end, as a thermal conduction part, disposed between the respective battery cells and the other end, as a heat dissipation part, protruding outward from each of the cartridges,and further comprising a first plate and a second plate mounted at outermost battery cells of the battery cell stack structure for fixing the battery cell stack structure wherein the heat dissipation part of the cooling plate is repeatedly bent such that an area of the heat dissipation part contacting external air is increased, and the battery module is characterized in that the first plate and the second plate are bent to cover the heat dissipation parts of the cooling plates. two or more stacked battery cells which can be charged and discharged; and cartridges for fixing the respective battery cells to form a battery cell stack structure, wherein each of the cartridges is provided with a cooling plate having one end, as a thermal conduction part, disposed between the respective battery cells and the other end, as a heat dissipation part, protruding outward from each of the cartridges,and further comprising a first plate and a second plate mounted at outermost battery cells of the battery cell stack structure for fixing the battery cell stack structure wherein the heat dissipation part of the cooling plate is repeatedly bent such that an area of the heat dissipation part contacting external air is increased, and the battery module is characterized in that the first plate and the second plate are bent to cover the heat dissipation parts of the cooling plates.