A system for mapping a patient data structure for describing a patient's case into a guideline data structure for describing a medical guideline, the system comprising a user interface for receiving user input comprising data items (DI1; DI3; DI5; DI27; DI47, DI67, DI74) of a plurality of data items (DI1; DI2;...; DI99) for the patient data structure and storage for storing: - the plurality of data items (DI1; DI2;...; DI99); - the patient data structure comprising the data items (DI1; DI3; DI5; DI27; DI47, DI67, DI74) of the plurality of data items (DI1; DI2;...; DI99); - the guideline data structure comprising a guideline graph, wherein the guideline graph is a directed graph, the guideline graph comprising action nodes (AN1; AN2), wherein each action node (AN1; AN2) is associated with an action, wherein an action associated with each action node comprises to perform a measurement on and/or apply a treatment to the patient; - the system further comprising a linker for linking data items (DI1; DI3; DI5; DI27; DI47, DI67, DI74) comprised in the patient data structure to action nodes (AN1; AN2) of the guideline graph, based on a relation between said data items and actions associated with said action nodes (AN1; AN2), thereby mapping the patient data structure into the guideline data structure, wherein the relation between the data items and actions comprises a measurement outcome for the action to perform a measurement and/or parameters of the applied treatment for the action to apply a treatment to the patient; wherein the system is adapted such that the receiving of the user input comprising the data items (DI1; DI3; DI5; DI27; DI47, DI67, DI74) of the patient data structure and the guideline graph are decoupled and such that the user input, which comprises the data items (DI1; DI3; DI5; DI27; DI47, DI67, DI74) of the patient data structure, is receivable out of an order of the action nodes defined by the guideline graph; - the system further comprising a pathway finder for computing a pathway of the patient in the guideline graph, the pathway comprising the action nodes (AN1; AN2) to which data items comprised in the patient data structure are linked, and wherein the pathway is determined by data items comprised in the patient data structure and the relation between said data items and actions associated with the action nodes comprised in the guideline graph, wherein the pathway provides an overview of a personalized medical guideline showing actions which have already been completed and which need to be completed. - the plurality of data items (DI1; DI2;...; DI99); - the patient data structure comprising the data items (DI1; DI3; DI5; DI27; DI47, DI67, DI74) of the plurality of data items (DI1; DI2;...; DI99); - the guideline data structure comprising a guideline graph, wherein the guideline graph is a directed graph, the guideline graph comprising action nodes (AN1; AN2), wherein each action node (AN1; AN2) is associated with an action, wherein an action associated with each action node comprises to perform a measurement on and/or apply a treatment to the patient; - the system further comprising a linker for linking data items (DI1; DI3; DI5; DI27; DI47, DI67, DI74) comprised in the patient data structure to action nodes (AN1; AN2) of the guideline graph, based on a relation between said data items and actions associated with said action nodes (AN1; AN2), thereby mapping the patient data structure into the guideline data structure, wherein the relation between the data items and actions comprises a measurement outcome for the action to perform a measurement and/or parameters of the applied treatment for the action to apply a treatment to the patient; wherein the system is adapted such that the receiving of the user input comprising the data items (DI1; DI3; DI5; DI27; DI47, DI67, DI74) of the patient data structure and the guideline graph are decoupled and such that the user input, which comprises the data items (DI1; DI3; DI5; DI27; DI47, DI67, DI74) of the patient data structure, is receivable out of an order of the action nodes defined by the guideline graph; - the system further comprising a pathway finder for computing a pathway of the patient in the guideline graph, the pathway comprising the action nodes (AN1; AN2) to which data items comprised in the patient data structure are linked, and wherein the pathway is determined by data items comprised in the patient data structure and the relation between said data items and actions associated with the action nodes comprised in the guideline graph, wherein the pathway provides an overview of a personalized medical guideline showing actions which have already been completed and which need to be completed.