A system comprising a syringe adapter tool for a catheter and a catheter; the catheter including an elongate lumen and a proximal terminal end that defines a proximal opening into the lumen, the lumen including a proximal port portion and a seal zone portion, the proximal port portion extending distally from the proximal opening and the seal zone portion extending distally from the proximal port portion; and the adapter tool comprising: a distal tip segment including a channel extending therein, the distal tip segment being sized to pass through the seal zone portion of the lumen of the catheter; at least one feature configured to interlock with the catheter in proximity to the proximal terminal end of the catheter; and a proximal attachment segment including a bore communicating with the channel of the distal tip segment, the bore having a proximal opening sized to accommodate insertion therein of a standard tapered tip of a syringe so that fluid from the syringe can be injected through the channel of the distal tip segment; and wherein the distal tip segment extends from the at least one feature in a first direction and the proximal attachment segment extends from the at least one feature in a second direction, opposite the first direction; and when at least one of the at least one feature interlocks with the catheter, the distal tip segment extends through the seal zone portion of the lumen of the catheter, the proximal attachment segment extends outside the catheter, and a torsional force can be transferred to the catheter, through the tool, from the syringe, when the tip of the syringe is inserted in the bore of the tool; and wherein: the channel of the distal tip segment is sized to accommodate passage of an instrument therethrough; and characterized in that the tool further comprises an instrument loading segment extending between the distal tip segment and the proximal attachment segment, the loading segment including a passageway into the channel of the distal tip segment, the passageway being accessible from an exterior of the tool and accommodating passage of the instrument therethrough; and wherein the distal tip segment further includes a slit extending through a sidewall thereof and along a length thereof, from a distal opening of the channel to the passageway of the instrument loading segment. a distal tip segment including a channel extending therein, the distal tip segment being sized to pass through the seal zone portion of the lumen of the catheter; at least one feature configured to interlock with the catheter in proximity to the proximal terminal end of the catheter; and a proximal attachment segment including a bore communicating with the channel of the distal tip segment, the bore having a proximal opening sized to accommodate insertion therein of a standard tapered tip of a syringe so that fluid from the syringe can be injected through the channel of the distal tip segment; and wherein the distal tip segment extends from the at least one feature in a first direction and the proximal attachment segment extends from the at least one feature in a second direction, opposite the first direction; and when at least one of the at least one feature interlocks with the catheter, the distal tip segment extends through the seal zone portion of the lumen of the catheter, the proximal attachment segment extends outside the catheter, and a torsional force can be transferred to the catheter, through the tool, from the syringe, when the tip of the syringe is inserted in the bore of the tool; and wherein: the channel of the distal tip segment is sized to accommodate passage of an instrument therethrough; and characterized in that the tool further comprises an instrument loading segment extending between the distal tip segment and the proximal attachment segment, the loading segment including a passageway into the channel of the distal tip segment, the passageway being accessible from an exterior of the tool and accommodating passage of the instrument therethrough; and wherein the distal tip segment further includes a slit extending through a sidewall thereof and along a length thereof, from a distal opening of the channel to the passageway of the instrument loading segment. the channel of the distal tip segment is sized to accommodate passage of an instrument therethrough; and characterized in that the tool further comprises an instrument loading segment extending between the distal tip segment and the proximal attachment segment, the loading segment including a passageway into the channel of the distal tip segment, the passageway being accessible from an exterior of the tool and accommodating passage of the instrument therethrough; and wherein the distal tip segment further includes a slit extending through a sidewall thereof and along a length thereof, from a distal opening of the channel to the passageway of the instrument loading segment.