A beam-to-column connection system, comprising: a first pair of splice plates configured to be secured to the column and to be spaced from each other along the column at a first distance; a second pair of splice plates configured to be secured to the column and opposite to the first pair of splice plates, and to be spaced from each other along the column at the first distance; a first seismic fuse plate exhibiting a single piece construction, the first seismic fuse plate including: a beam-connection portion configured to be fastened to a first flange of the beam; the beam-to-column connection system being characterised in that said first seismic fuse plate further includes: a first splice-connection portion longitudinally extending along at least a portion of the beam-connection portion and being configured to be fastened to and between the first pair of splice plates; a second splice-connection portion longitudinally extending along at least a portion of the beam-connection portion and being configured to be fastened to and between the second pair of splice plates at a second location, the distance between the first and second location being greater than the width of the beam; and a first shear portion extending between the first splice-connection portion and the beam-connection portion, the first shear portion configured to preferentially fail or deform before the column and the beam. a first pair of splice plates configured to be secured to the column and to be spaced from each other along the column at a first distance; a second pair of splice plates configured to be secured to the column and opposite to the first pair of splice plates, and to be spaced from each other along the column at the first distance; a first seismic fuse plate exhibiting a single piece construction, the first seismic fuse plate including: a beam-connection portion configured to be fastened to a first flange of the beam; the beam-to-column connection system being characterised in that said first seismic fuse plate further includes: a first splice-connection portion longitudinally extending along at least a portion of the beam-connection portion and being configured to be fastened to and between the first pair of splice plates; a second splice-connection portion longitudinally extending along at least a portion of the beam-connection portion and being configured to be fastened to and between the second pair of splice plates at a second location, the distance between the first and second location being greater than the width of the beam; and a first shear portion extending between the first splice-connection portion and the beam-connection portion, the first shear portion configured to preferentially fail or deform before the column and the beam. a first splice-connection portion longitudinally extending along at least a portion of the beam-connection portion and being configured to be fastened to and between the first pair of splice plates; a second splice-connection portion longitudinally extending along at least a portion of the beam-connection portion and being configured to be fastened to and between the second pair of splice plates at a second location, the distance between the first and second location being greater than the width of the beam; and a first shear portion extending between the first splice-connection portion and the beam-connection portion, the first shear portion configured to preferentially fail or deform before the column and the beam.