A compound of Formula: or a pharmaceutically acceptable salt or quaternary amine salt thereof; wherein: m is 0, 1, 2, 3, or 4; R 1 and R 2 are joined to form a ring of Formula: n is 0, 1, 2, 3 or 4; each instance of R 6A is independently halogen, -NO 2, -CN, -OR 6C, SR 6C, N(R 6C) 2, - C(=O)R 6C, -C(=O)OR 6C, -C(=O)N(R 6C) 2, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, optionally substituted aryl, or optionally substituted heteroaryl; wherein each instance of R 6C is independently hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, optionally substituted aryl, optionally substituted heteroaryl, an oxygen protecting group when attached to oxygen, a sulfur protecting group when attached to sulfur, or a nitrogen protecting group when attached to nitrogen, optionally when attached to N the two R 6C groups may be joined to form an optionally substituted heterocyclyl or optionally substituted heteroaryl ring; G is -O-, -S-, -NH-, -NR 7-, -CH 2 -, -CH(R 7)-, or -C(R 7) 2 -; each instance of R 7 is independently amino, hydroxyl, halogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, optionally substituted aryl, optionally substituted heteroaryl, substituted amino, substituted hydroxyl, thiol, substituted thiol, carbonyl, sulfonyl, sulfinyl, or a nitrogen protecting group when attached to a nitrogen atom; and optionally wherein two R 7 groups are joined to form an optionally substituted carbocyclyl, optionally substituted heterocyclyl, optionally substituted aryl, or optionally substituted heteroaryl ring, or an oxo (=O) group. m is 0, 1, 2, 3, or 4; R 1 and R 2 are joined to form a ring of Formula: n is 0, 1, 2, 3 or 4; each instance of R 6A is independently halogen, -NO 2, -CN, -OR 6C, SR 6C, N(R 6C) 2, - C(=O)R 6C, -C(=O)OR 6C, -C(=O)N(R 6C) 2, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, optionally substituted aryl, or optionally substituted heteroaryl; wherein each instance of R 6C is independently hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, optionally substituted aryl, optionally substituted heteroaryl, an oxygen protecting group when attached to oxygen, a sulfur protecting group when attached to sulfur, or a nitrogen protecting group when attached to nitrogen, optionally when attached to N the two R 6C groups may be joined to form an optionally substituted heterocyclyl or optionally substituted heteroaryl ring; G is -O-, -S-, -NH-, -NR 7-, -CH 2 -, -CH(R 7)-, or -C(R 7) 2 -; each instance of R 7 is independently amino, hydroxyl, halogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, optionally substituted aryl, optionally substituted heteroaryl, substituted amino, substituted hydroxyl, thiol, substituted thiol, carbonyl, sulfonyl, sulfinyl, or a nitrogen protecting group when attached to a nitrogen atom; and optionally wherein two R 7 groups are joined to form an optionally substituted carbocyclyl, optionally substituted heterocyclyl, optionally substituted aryl, or optionally substituted heteroaryl ring, or an oxo (=O) group. n is 0, 1, 2, 3 or 4; each instance of R 6A is independently halogen, -NO 2, -CN, -OR 6C, SR 6C, N(R 6C) 2, - C(=O)R 6C, -C(=O)OR 6C, -C(=O)N(R 6C) 2, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, optionally substituted aryl, or optionally substituted heteroaryl; wherein each instance of R 6C is independently hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, optionally substituted aryl, optionally substituted heteroaryl, an oxygen protecting group when attached to oxygen, a sulfur protecting group when attached to sulfur, or a nitrogen protecting group when attached to nitrogen, optionally when attached to N the two R 6C groups may be joined to form an optionally substituted heterocyclyl or optionally substituted heteroaryl ring; G is -O-, -S-, -NH-, -NR 7-, -CH 2 -, -CH(R 7)-, or -C(R 7) 2 -; each instance of R 7 is independently amino, hydroxyl, halogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, optionally substituted aryl, optionally substituted heteroaryl, substituted amino, substituted hydroxyl, thiol, substituted thiol, carbonyl, sulfonyl, sulfinyl, or a nitrogen protecting group when attached to a nitrogen atom; and optionally wherein two R 7 groups are joined to form an optionally substituted carbocyclyl, optionally substituted heterocyclyl, optionally substituted aryl, or optionally substituted heteroaryl ring, or an oxo (=O) group.