A heat exchange device, comprising: a center manifold configured to allow fluid to enter the manifold through at least one first plenum at a first side, pass into a first and a second section (102, 104) disposed on either side of the center manifold, and return to the center manifold to exit the center manifold at a second side through a second plenum; the center manifold being disposed between the first and second sections (102, 104), each of the first and second sections including flow passages configured to exchange heat between heat exchange fluid within the flow passages and fluid external of the flow passages, wherein each of the flow passages have a first end and a second end; wherein each of the first ends includes a fluid inlet (12, 120) directing flow from the center manifold into the flow passage and each of the second ends includes a fluid outlet (14, 122) directing flow from the flow passage to the center manifold; wherein the fluid inlet (12, 120) and the fluid outlet (14, 122) of adjacent flow passages are opposite in flow direction of one another; and wherein adjacent ends of adjacent flow passages direct fluid flow in opposite directions, or wherein fluid inlets of adjacent flow passages are adjacent one another, and wherein fluid outlets of adjacent flow passages are adjacent one another the center manifold further comprising a plurality of angled or curved separators within the center manifold connected to one another by arcuate segments arranged at alternating ends of the separators along a height of the center manifold, the separators being configured to separate the inlets and outlets (12, 14) of the flow passages in which fluid flows in the opposite direction; characterized in that the center manifold further comprises a plurality of angled center manifold plates, wherein the downstream end of each of the angled center manifold plates abuts an arcuate segment connecting adjacent separators. a center manifold configured to allow fluid to enter the manifold through at least one first plenum at a first side, pass into a first and a second section (102, 104) disposed on either side of the center manifold, and return to the center manifold to exit the center manifold at a second side through a second plenum; the center manifold being disposed between the first and second sections (102, 104), each of the first and second sections including flow passages configured to exchange heat between heat exchange fluid within the flow passages and fluid external of the flow passages, wherein each of the flow passages have a first end and a second end; wherein each of the first ends includes a fluid inlet (12, 120) directing flow from the center manifold into the flow passage and each of the second ends includes a fluid outlet (14, 122) directing flow from the flow passage to the center manifold; wherein the fluid inlet (12, 120) and the fluid outlet (14, 122) of adjacent flow passages are opposite in flow direction of one another; and wherein adjacent ends of adjacent flow passages direct fluid flow in opposite directions, or wherein fluid inlets of adjacent flow passages are adjacent one another, and wherein fluid outlets of adjacent flow passages are adjacent one another the center manifold further comprising a plurality of angled or curved separators within the center manifold connected to one another by arcuate segments arranged at alternating ends of the separators along a height of the center manifold, the separators being configured to separate the inlets and outlets (12, 14) of the flow passages in which fluid flows in the opposite direction; characterized in that the center manifold further comprises a plurality of angled center manifold plates, wherein the downstream end of each of the angled center manifold plates abuts an arcuate segment connecting adjacent separators. a plurality of angled or curved separators within the center manifold connected to one another by arcuate segments arranged at alternating ends of the separators along a height of the center manifold, the separators being configured to separate the inlets and outlets (12, 14) of the flow passages in which fluid flows in the opposite direction; characterized in that the center manifold further comprises a plurality of angled center manifold plates, wherein the downstream end of each of the angled center manifold plates abuts an arcuate segment connecting adjacent separators.