mhurhangee/ep-ind-claims huggingface dataset:
An isolated double stranded RNA (dsRNA) comprising: i) a first strand wherein said first strand is 19-80 nucleotides in length, and ii) a second strand, wherein said second strand is 19-35 nucleotides in length, wherein with reference to any one of Figures 1A, 1B, 5A and 5B, the first and second strands form a duplex in Region B of 15-35 base pairs in length; wherein the first strand comprises a Region E at the 3' terminus, wherein Region E comprises a tetraloop; and the dsRNA comprises a discontinuity between the 3' terminus of the first strand and the 5' terminus of the second strand, wherein the the dsRNA decreases target gene expression in a mammalian cell. i) a first strand wherein said first strand is 19-80 nucleotides in length, and ii) a second strand, wherein said second strand is 19-35 nucleotides in length, wherein with reference to any one of Figures 1A, 1B, 5A and 5B, the first and second strands form a duplex in Region B of 15-35 base pairs in length;
A vehicular multi-speed transmission including a shift mechanism, fork shafts, and a drum, wherein the shift mechanism is a parallel-shaft-type constant-mesh shift mechanism having a plurality of shift sleeves each configured to be moved in an axial direction of the shift mechanism so as to change a gear position, the fork shafts being provided with shift forks and projections corresponding to the respective shift sleeves, the shift forks being configured to move the shift sleeves in the axial direction of the shift mechanism, and projections protruding radially outward the respective fork shafts, the drum being mounted rotatably about an axis parallel to the fork shafts, the drum being provided at an outer circumferential surface with a plurality of grooves corresponding to the respective shift sleeves, and the grooves being configured to receive the projections such that each of the projections can slide in a circumferential direction of the drum, wherein: the drum includes a plurality of shift drums, a base drum, and a lock mechanism, the shift drums being (i) separately provided for the respective grooves, and (ii) located at predetermined intervals in an axial direction of the base drum, the base drum being (i) rotatably supported by a stationary member, coaxially with the shift drums, in a space radially inside of the shift drums, and (ii) configured to hold the shift drums such that the shift drums cannot rotate relative to the base drum and the shift drums can move independently in the axial direction of the base drum relative to the base drum; and the lock mechanism is configured to switch the shift drum between a locked state and a free state, the locked state being a state in which the shift drum cannot move relative to the base drum in the axial direction of the base drum, the free state being a state in which the shift drum can move relative to the base drum in the axial direction of the base drum; the vehicular multi-speed transmission being characterized in that the lock mechanism is provided in the base drum for each of the shift drums. the drum includes a plurality of shift drums, a base drum, and a lock mechanism, the shift drums being (i) separately provided for the respective grooves, and (ii) located at predetermined intervals in an axial direction of the base drum, the base drum being (i) rotatably supported by a stationary member, coaxially with the shift drums, in a space radially inside of the shift drums, and (ii) configured to hold the shift drums such that the shift drums cannot rotate relative to the base drum and the shift drums can move independently in the axial direction of the base drum relative to the base drum; and the lock mechanism is configured to switch the shift drum between a locked state and a free state, the locked state being a state in which the shift drum cannot move relative to the base drum in the axial direction of the base drum, the free state being a state in which the shift drum can move relative to the base drum in the axial direction of the base drum;
A compound of formula Ia or Ib for use in diagnostic imaging of a cell or population of cells expressing a folate-receptor in vitro or in vivo or for use in monitoring of cancer or inflammatory and autoimmune diseases and therapy thereof wherein R 1, R 2 are independently of each other H or straight chain or branched C1-C6 alkyl, and R 3, R 4 are independently of each other H, formyl, or methyl, or a pharmaceutically acceptable salt thereof. R 1, R 2 are independently of each other H or straight chain or branched C1-C6 alkyl, and R 3, R 4 are independently of each other H, formyl, or methyl,
An ignition unit adapted to produce an ignition in a combustion chamber of a combustion engine, the ignition unit comprising: - a signal input connection; - a radiofrequency resonator (117, 118) adapted to radiate a plasma-creating radiofrequency field into the combustion chamber; and - a microwave resonator adapted to radiate a plasma-boosting microwave field into the combustion chamber, the microwave resonator comprising an output surface to which the combustion chamber is exposed when the ignition unit is fitted on the combustion engine, - characterised in that the radiofrequency resonator comprises: - - an electrode that is at least partially embedded in the microwave resonator; and - a winding that couples the signal input connection to the electrode, the winding being surrounded by a cylindrical tube, the winding being adapted to form a microwave transmission path between the signal input connection and the microwave resonator, the microwave transmission path being formed by one of the two following volumes: an outer volume between the winding and the cylindrical tube, and an inner volume of the winding. - a signal input connection; - a radiofrequency resonator (117, 118) adapted to radiate a plasma-creating radiofrequency field into the combustion chamber; and - a microwave resonator adapted to radiate a plasma-boosting microwave field into the combustion chamber, the microwave resonator comprising an output surface to which the combustion chamber is exposed when the ignition unit is fitted on the combustion engine, - characterised in that - - an electrode that is at least partially embedded in the microwave resonator; and - a winding that couples the signal input connection to the electrode, the winding being surrounded by a cylindrical tube, the winding being adapted to form a microwave transmission path between the signal input connection and the microwave resonator, the microwave transmission path being formed by one of the two following volumes: an outer volume between the winding and the cylindrical tube, and an inner volume of the winding.
A computer-implemented method in a cloud computing environment including at least first and second partners (A, B, C) that share a distributed file system, wherein: a. one or more Trading Partner Agreements (TPAs) are negotiated between two or more of the at least first and second partners (A, B, C), each said TPA specifying: any resources allocated by the partners (A, B, C) in the TPA, a transport protocol to be used by the partners (A, B, C) in the TPA, and a security mechanism to be used by the partners (A, B, C) in the TPA; and wherein a security policy is formed from the TPAs; characterized in that the method further comprises: b. running an algorithm to determine a target partner or target partner instance to which an executable code from a source partner or source partner instance is to be distributed; c. transferring the executable code to the target partner or target partner instance in accordance with a TPA negotiated between the target partner or target partner instance and the source partner or source partner instance; and d. invoking the executable code on the target partner or target partner instance within constraints specified by the security policy. a. one or more Trading Partner Agreements (TPAs) are negotiated between two or more of the at least first and second partners (A, B, C), each said TPA specifying: any resources allocated by the partners (A, B, C) in the TPA, a transport protocol to be used by the partners (A, B, C) in the TPA, and a security mechanism to be used by the partners (A, B, C) in the TPA; and wherein a security policy is formed from the TPAs; any resources allocated by the partners (A, B, C) in the TPA, a transport protocol to be used by the partners (A, B, C) in the TPA, and a security mechanism to be used by the partners (A, B, C) in the TPA; and wherein a security policy is formed from the TPAs; b. running an algorithm to determine a target partner or target partner instance to which an executable code from a source partner or source partner instance is to be distributed; c. transferring the executable code to the target partner or target partner instance in accordance with a TPA negotiated between the target partner or target partner instance and the source partner or source partner instance; and d. invoking the executable code on the target partner or target partner instance within constraints specified by the security policy.
Device for producing a tyre component by winding, characterized in that it comprises: - a helicoidal external wall, and - means for adjusting a diameter of the wall. - a helicoidal external wall, and - means for adjusting a diameter of the wall.
Arrangement for storing and transporting at least one security, having at least one transportation container for storing and for transporting the at least one security, having a receptacle unit (10, 44) for receiving the transportation container, wherein the transportation container has an information item carrier with at least one first machine-readable information item, wherein the first information item is an identifier of the transportation container, and wherein the transportation container has a first data transmission unit, and the receptacle unit (10, 44) has a second data transmission unit, characterized in that the receptacle unit (10, 44) has a reading unit for reading the identifier of the transportation container from the information item carrier, in that a control unit which is assigned to the receptacle unit is provided, said control unit processing the read identifier and generating a processed, second information item as a function of the read identifier of the transportation container, in that data with the second information item can be transmitted at least from the second data transmission unit to the first data transmission unit, and in that a data processing unit of the transportation container checks the second information item, wherein when a second information item is not correct, manipulation of the transportation container is detected.
A method of making a wind turbine blade, the method comprising: a. providing a first half shell and a second half shell to be joined together to form the wind turbine blade, the half shells (32a, 32b) each extending in a longitudinal direction; b. attaching a first edge of a shear web (42a, 42b) to an inner surface of the first half shell; c. defining a shear web mounting region (62a, 62b) on an inner surface of the second half shell; d. attaching at least one guide block (60a, 60b) to the inner surface of the second half shell adjacent to the shear web mounting region (62a, 62b), the guide block (60a, 60b) having a guide surface oriented transversely to the inner surface of the second half shell; e. bringing the first and second half shells (32a, 32b) together whilst guiding a second edge of the shear web (42a, 42b) over the guide surface of the mounting block (60a, 60b) towards the shear web mounting region (62a, 62b) defined on the inner surface of the second half shell; and f. attaching the second edge of the shear web (42a, 42b) to the shear web mounting region (62a, 62b) of the second half shell. a. providing a first half shell and a second half shell to be joined together to form the wind turbine blade, the half shells (32a, 32b) each extending in a longitudinal direction; b. attaching a first edge of a shear web (42a, 42b) to an inner surface of the first half shell; c. defining a shear web mounting region (62a, 62b) on an inner surface of the second half shell; d. attaching at least one guide block (60a, 60b) to the inner surface of the second half shell adjacent to the shear web mounting region (62a, 62b), the guide block (60a, 60b) having a guide surface oriented transversely to the inner surface of the second half shell; e. bringing the first and second half shells (32a, 32b) together whilst guiding a second edge of the shear web (42a, 42b) over the guide surface of the mounting block (60a, 60b) towards the shear web mounting region (62a, 62b) defined on the inner surface of the second half shell; and f. attaching the second edge of the shear web (42a, 42b) to the shear web mounting region (62a, 62b) of the second half shell.
A resource state acquisition method comprising: receiving a resource state report request message including basic resource information from a first Evolved Node Base called a first eNB, the basic resource information being configured to indicate basic resources required to be provided by a second eNB, and the basic resources being resources required by load balance; and judging whether the second eNB can provide the basic resources according to the basic resource information, and when the second eNB cannot provide the basic resources, sending a resource state failure message to the first eNB; and wherein the resource state report request message further comprises requested resource type information; the requested resource type information is configured to represent requested resources required to be provided by the second eNB; and the basic resource information is indication information which indicates whether each requested resource is a basic resource. receiving a resource state report request message including basic resource information from a first Evolved Node Base called a first eNB, the basic resource information being configured to indicate basic resources required to be provided by a second eNB, and the basic resources being resources required by load balance; and judging whether the second eNB can provide the basic resources according to the basic resource information, and when the second eNB cannot provide the basic resources, sending a resource state failure message to the first eNB; and wherein the resource state report request message further comprises requested resource type information; the requested resource type information is configured to represent requested resources required to be provided by the second eNB; and the basic resource information is indication information which indicates whether each requested resource is a basic resource.
A pharmaceutical dosage form that is suitable for peroral administration to the gastrointestinal tract, which dosage form comprises a pharmaceutical composition in the form of a particulate mixture comprising: (a) solid particles of N-butyloxycarbonyl-3-(4-imidazol-1-ylmethylphenyl)-5-iso-butylthiophene-2-sulfonamide sodium salt, admixed with (b) a blend of: (i) carrier particles having a weight- based mean diameter and/or a volume-based mean diameter that that is less than about 100 μm, and a structural/particle density that is within about ±20% of the structural/particle density of the solid particles of N-butyloxycarbonyl-3-(4-imidazol-1-ylmethylphenyl)-5-iso-butylthiophene-2-sulfonamide sodium salt, and (ii) a glidant, which composition is contained within a capsule that is suitable for such peroral administration. (a) solid particles of N-butyloxycarbonyl-3-(4-imidazol-1-ylmethylphenyl)-5-iso-butylthiophene-2-sulfonamide sodium salt, admixed with (b) a blend of: (i) carrier particles having a weight- based mean diameter and/or a volume-based mean diameter that that is less than about 100 μm, and a structural/particle density that is within about ±20% of the structural/particle density of the solid particles of N-butyloxycarbonyl-3-(4-imidazol-1-ylmethylphenyl)-5-iso-butylthiophene-2-sulfonamide sodium salt, and (ii) a glidant, (i) carrier particles having a weight- based mean diameter and/or a volume-based mean diameter that that is less than about 100 μm, and a structural/particle density that is within about ±20% of the structural/particle density of the solid particles of N-butyloxycarbonyl-3-(4-imidazol-1-ylmethylphenyl)-5-iso-butylthiophene-2-sulfonamide sodium salt, and (ii) a glidant,
Cosmetic oral use of glucosamine comprising all its salified, acetylated and/or polymeric forms in the prevention and/or treatment of loss of skin firmness induced by menopause.
Protection equipment for protecting a person in an emergency, the protection equipment comprising a securing device which is wearable by the person with a securing system for protecting the person in an emergency, wherein the wearable securing device is a rope protection, in particular a safety belt, a sensor unit for detecting a dangerous situation prior to an emergency of the person, wherein the sensor unit is coupled with the securing system directly or via a control unit, such that the sensor unit itself or the control unit function as a command provider for the securing system, such that, when detecting the dangerous situation for the person, the sensor unit automatically adjusts the securing system to a securing state for protecting the person prior to the emergency, wherein the sensor unit comprises a distance sensor for measuring a distance to a falling edge as a danger location, wherein the securing system comprises a fall protection, wherein the fall protection comprises a rope winch, on which a safety rope is wound up, wherein the rope winch of the fall protection is provided with the safety rope, and is configured to control the length of a rope length of the safety rope between the wearable securing device and a securing point for fixing the safety rope, wherein the fall protection is coupled with the sensor unit, such that the rope length is controllable depending on the detection of the dangerous situation, in which the distance of the person to a falling edge is below a boundary value. a securing device which is wearable by the person with a securing system for protecting the person in an emergency, wherein the wearable securing device is a rope protection, in particular a safety belt, a sensor unit for detecting a dangerous situation prior to an emergency of the person, wherein the sensor unit is coupled with the securing system directly or via a control unit, such that the sensor unit itself or the control unit function as a command provider for the securing system, such that, when detecting the dangerous situation for the person, the sensor unit automatically adjusts the securing system to a securing state for protecting the person prior to the emergency, wherein the sensor unit comprises a distance sensor for measuring a distance to a falling edge as a danger location, wherein the securing system comprises a fall protection, wherein the fall protection comprises a rope winch, on which a safety rope is wound up, wherein the rope winch of the fall protection is provided with the safety rope, and is configured to control the length of a rope length of the safety rope between the wearable securing device and a securing point for fixing the safety rope, wherein the fall protection is coupled with the sensor unit, such that the rope length is controllable depending on the detection of the dangerous situation, in which the distance of the person to a falling edge is below a boundary value.
System for dispensing a pressurised product comprising a body equipped with means making it possible to supply an inner chamber of said body with product coming from a source, said system also comprising a rod on which is mounted a pushbutton to be actuated reversibly in translation in said body, said rod being equipped with a valve which is arranged in the inner chamber having a stable state for closing a dispensing path formed through the rod and the pushbutton up to a dispensing orifice, and a state constrained by actuation of the rod wherein said dispensing path is in communication with the inner chamber, said pushbutton having a housing in which is mounted a nozzle provided with the dispensing orifice, said system being characterised in that the nozzle is made, of a material comprising at least one polyolefin which is loaded with at least one cyclic olefin copolymer COC.
A method of recovering copper from sulfide ores with copper and iron, the method comprising: reacting, in a reaction vessel, a copper-containing sulfide ore with sulfur dioxide gas at a temperature of 120°C to 140°C, and a residence time of less than 2 hours, to form a reaction mixture comprising elemental sulfur and residual solids, the residual solids comprising an iron oxide and a copper sulfide; condensing and removing the elemental sulfur from the reaction mixture; reacting residual solids remaining in the reaction mixture with concentrated sulfuric acid to form copper sulfate and sulfur dioxide gas; recycling the sulfur dioxide gas; separating solids comprising the iron oxide and copper sulfate from a liquid phase of the reaction mixture; drying the separated solids; leaching the dried solids with an aqueous solution comprising water or dilute sulfuric acid and solubilizing the copper sulfate; separating the solids comprising the iron oxide and gangue from a liquid phase of the reaction mixture; and recovering copper from the solubilized copper sulfate. reacting, in a reaction vessel, a copper-containing sulfide ore with sulfur dioxide gas at a temperature of 120°C to 140°C, and a residence time of less than 2 hours, to form a reaction mixture comprising elemental sulfur and residual solids, the residual solids comprising an iron oxide and a copper sulfide; condensing and removing the elemental sulfur from the reaction mixture; reacting residual solids remaining in the reaction mixture with concentrated sulfuric acid to form copper sulfate and sulfur dioxide gas; recycling the sulfur dioxide gas; separating solids comprising the iron oxide and copper sulfate from a liquid phase of the reaction mixture; drying the separated solids; leaching the dried solids with an aqueous solution comprising water or dilute sulfuric acid and solubilizing the copper sulfate; separating the solids comprising the iron oxide and gangue from a liquid phase of the reaction mixture; and recovering copper from the solubilized copper sulfate.
A wound dressing assembly, comprising a clotting mold device comprising a cavity defined by concave walls surrounded by lips configured for attachment to skin in a fluid tight manner, wherein, for introducing blood into the cavity once said lips are attached to the skin, the concave walls of the clotting mold device comprise one of (i) a portion being pierceable and suitable for introducing blood into the cavity, and (ii) a port suitable for introducing said blood into the cavity; a device for introducing blood into the cavity after it is fixed over a wound to permit the blood to come into contact with the wound and to clot over the wound within said cavity; a blood coagulation initiator. a clotting mold device comprising a cavity defined by concave walls surrounded by lips configured for attachment to skin in a fluid tight manner, wherein, for introducing blood into the cavity once said lips are attached to the skin, the concave walls of the clotting mold device comprise one of (i) a portion being pierceable and suitable for introducing blood into the cavity, and (ii) a port suitable for introducing said blood into the cavity; a device for introducing blood into the cavity after it is fixed over a wound to permit the blood to come into contact with the wound and to clot over the wound within said cavity; a blood coagulation initiator.