A glucose monitoring assembly, the assembly comprising: an inserter (200, 300, 400, 2400, 2500, 2700, 3700, 3700'), comprising: an inserter housing (202, 302, 402, 2402, 2502, 2702, 3702); a sharp (224, 324, 424, 2404, 2550), wherein the sharp is configured to insert a portion of a glucose sensor into a subject; and a carrier (230, 330, 430, 2730, 3730) detachably engaged with a plurality of recesses (3766, 3766') of an on body electronics unit housing (122, 322, 3800, 4200), wherein the carrier (230, 330, 430, 2730, 3730) comprises a plurality of gripping arms (3762, 3762'); an on body electronics unit, comprising: the on body electronics unit housing comprising the plurality of recesses circumferentially disposed thereon, wherein the plurality of recesses comprises a first recess in a spaced relation to a second recess; the glucose sensor; and on body electronics coupled with the glucose sensor, wherein the on body electronics is disposed within the on body electronics unit housing, and wherein the on body electronics includes a processor, memory, a power supply, and wireless communication circuitry configured to wirelessly communicate data indicative of a glucose level; wherein the inserter is configured to advance the on body electronics unit and the sharp from a proximal position entirely within the inserter to a distal position, wherein each gripping arm of the plurality of gripping arms (3762, 3762') is configured to be engaged with a corresponding recess of the plurality of recesses (3766, 3766') of the on body electronics unit housing when the on body electronics unit is in the proximal position, and wherein the inserter is further configured to retract the sharp from the distal position to a retracted position entirely within the inserter. an inserter (200, 300, 400, 2400, 2500, 2700, 3700, 3700'), comprising: an inserter housing (202, 302, 402, 2402, 2502, 2702, 3702); a sharp (224, 324, 424, 2404, 2550), wherein the sharp is configured to insert a portion of a glucose sensor into a subject; and a carrier (230, 330, 430, 2730, 3730) detachably engaged with a plurality of recesses (3766, 3766') of an on body electronics unit housing (122, 322, 3800, 4200), wherein the carrier (230, 330, 430, 2730, 3730) comprises a plurality of gripping arms (3762, 3762'); an inserter housing (202, 302, 402, 2402, 2502, 2702, 3702); a sharp (224, 324, 424, 2404, 2550), wherein the sharp is configured to insert a portion of a glucose sensor into a subject; and a carrier (230, 330, 430, 2730, 3730) detachably engaged with a plurality of recesses (3766, 3766') of an on body electronics unit housing (122, 322, 3800, 4200), wherein the carrier (230, 330, 430, 2730, 3730) comprises a plurality of gripping arms (3762, 3762'); an on body electronics unit, comprising: the on body electronics unit housing comprising the plurality of recesses circumferentially disposed thereon, wherein the plurality of recesses comprises a first recess in a spaced relation to a second recess; the glucose sensor; and on body electronics coupled with the glucose sensor, wherein the on body electronics is disposed within the on body electronics unit housing, and wherein the on body electronics includes a processor, memory, a power supply, and wireless communication circuitry configured to wirelessly communicate data indicative of a glucose level; wherein the inserter is configured to advance the on body electronics unit and the sharp from a proximal position entirely within the inserter to a distal position, wherein each gripping arm of the plurality of gripping arms (3762, 3762') is configured to be engaged with a corresponding recess of the plurality of recesses (3766, 3766') of the on body electronics unit housing when the on body electronics unit is in the proximal position, and wherein the inserter is further configured to retract the sharp from the distal position to a retracted position entirely within the inserter. the on body electronics unit housing comprising the plurality of recesses circumferentially disposed thereon, wherein the plurality of recesses comprises a first recess in a spaced relation to a second recess; the glucose sensor; and on body electronics coupled with the glucose sensor, wherein the on body electronics is disposed within the on body electronics unit housing, and wherein the on body electronics includes a processor, memory, a power supply, and wireless communication circuitry configured to wirelessly communicate data indicative of a glucose level; wherein the inserter is configured to advance the on body electronics unit and the sharp from a proximal position entirely within the inserter to a distal position, wherein each gripping arm of the plurality of gripping arms (3762, 3762') is configured to be engaged with a corresponding recess of the plurality of recesses (3766, 3766') of the on body electronics unit housing when the on body electronics unit is in the proximal position, and wherein the inserter is further configured to retract the sharp from the distal position to a retracted position entirely within the inserter. wherein the inserter is configured to advance the on body electronics unit and the sharp from a proximal position entirely within the inserter to a distal position, wherein each gripping arm of the plurality of gripping arms (3762, 3762') is configured to be engaged with a corresponding recess of the plurality of recesses (3766, 3766') of the on body electronics unit housing when the on body electronics unit is in the proximal position, and wherein the inserter is further configured to retract the sharp from the distal position to a retracted position entirely within the inserter.