Compounds represented by general formula wherein: R 1 is aryl C 1-6 alkyl unsubstituted or substituted by 1 to 3 substituents V, wherein the substituent V is independently selected from cyano, C 2-6 alkynyl, halogen atom, hydroxy, amino, carboxyl, C 1-6 alkyl, C 1-6 alkoxy, carbamoyl, cyano C 1-6 alkyl, halogen C 1-6 alkyl, hydroxy C 1-6 alkyl, amino C 1-6 alkyl, carboxyl C 1-6 alkyl, halogen C 1-6 alkoxy, C 1-6 alkylamino, C 1-6 alkoxyamino or di-(C 1-6 alkyl)amino; R 2 and R 3 are independently from each other hydrogen atom, halogen atom, cyano, amino, hydroxy, carboxyl, C 1-6 alkylamino, di-(C 1-6 alkyl)amino, C 1-6 alkyl or C 1-6 alkoxy unsubstituted or substituted by halogen atom, hydroxy, amino, or R 2 and R 3 together with the C atoms they are attached to form a phenyl, 5- to 6-membered saturated or unsaturated heterocyclyl group containing at least one nitrogen atom or C 3-6 cycloalkyl; X is NR 4, CR 5 R 6, O, or S, R 4 is selected from hydrogen atom, C 1-6 alkyl, halogen C 1-6 alkyl, C 2-6 alkenyl or C 3-6 cycloalkyl, R 5 and R 6 are independently selected from hydrogen atom, halogen atom, C 1-6 alkyl, halogen C 1-6 alkyl, C 1-6 alkoxy, halogen C 1-6 alkoxy or C 3-6 cycloalkyl, or R 5 and R 6 together with the C atoms they are attached to form C 3-6 cycloalkyl; Y is O, S or NR 7, R 7 is hydrogen atom, C 3-6 cycloalkyl, or C 1-6 alkyl, C 1-6 alkoxy, phenyl C 0-6 alkyl or phenyl C 0-6 alkoxy, which are unsubstituted or substituted by halogen atom, hydroxy, amino, carboxyl or carbamoyl; Q is 4- to 7-membered saturated or unsaturated heterocyclyl group containing at least one nitrogen atom, unsubstituted or substituted by 1 to 3 substituents W, the said substituent W is independently selected from halogen atom, amino, C 1-6 alkylamino, di-(C 1-6 alkyl)amino, amino C 1-6 alkyl, hydroxy C 1-6 alkyl, carboxyl C 1-6 alkyl, carbamoyl, C 1-6 alkyl, halogen C 1-6 alkyl, C 1-6 alkoxy, halogen C 1-6 alkoxy, formimino, C 1-6 alkylcarbonylaminomethyl, C 1-6 alkylcarbonyloxyl, C 1-6 alkylcarbamoyl or C 1-6 alkoxyformyl, their pharmaceutically acceptable salts, stereoisomers or solvates thereof. R 1 is aryl C 1-6 alkyl unsubstituted or substituted by 1 to 3 substituents V, wherein the substituent V is independently selected from cyano, C 2-6 alkynyl, halogen atom, hydroxy, amino, carboxyl, C 1-6 alkyl, C 1-6 alkoxy, carbamoyl, cyano C 1-6 alkyl, halogen C 1-6 alkyl, hydroxy C 1-6 alkyl, amino C 1-6 alkyl, carboxyl C 1-6 alkyl, halogen C 1-6 alkoxy, C 1-6 alkylamino, C 1-6 alkoxyamino or di-(C 1-6 alkyl)amino; R 2 and R 3 are independently from each other hydrogen atom, halogen atom, cyano, amino, hydroxy, carboxyl, C 1-6 alkylamino, di-(C 1-6 alkyl)amino, C 1-6 alkyl or C 1-6 alkoxy unsubstituted or substituted by halogen atom, hydroxy, amino, or R 2 and R 3 together with the C atoms they are attached to form a phenyl, 5- to 6-membered saturated or unsaturated heterocyclyl group containing at least one nitrogen atom or C 3-6 cycloalkyl; X is NR 4, CR 5 R 6, O, or S, R 4 is selected from hydrogen atom, C 1-6 alkyl, halogen C 1-6 alkyl, C 2-6 alkenyl or C 3-6 cycloalkyl, R 5 and R 6 are independently selected from hydrogen atom, halogen atom, C 1-6 alkyl, halogen C 1-6 alkyl, C 1-6 alkoxy, halogen C 1-6 alkoxy or C 3-6 cycloalkyl, or R 5 and R 6 together with the C atoms they are attached to form C 3-6 cycloalkyl; Y is O, S or NR 7, R 7 is hydrogen atom, C 3-6 cycloalkyl, or C 1-6 alkyl, C 1-6 alkoxy, phenyl C 0-6 alkyl or phenyl C 0-6 alkoxy, which are unsubstituted or substituted by halogen atom, hydroxy, amino, carboxyl or carbamoyl; Q is 4- to 7-membered saturated or unsaturated heterocyclyl group containing at least one nitrogen atom, unsubstituted or substituted by 1 to 3 substituents W, the said substituent W is independently selected from halogen atom, amino, C 1-6 alkylamino, di-(C 1-6 alkyl)amino, amino C 1-6 alkyl, hydroxy C 1-6 alkyl, carboxyl C 1-6 alkyl, carbamoyl, C 1-6 alkyl, halogen C 1-6 alkyl, C 1-6 alkoxy, halogen C 1-6 alkoxy, formimino, C 1-6 alkylcarbonylaminomethyl, C 1-6 alkylcarbonyloxyl, C 1-6 alkylcarbamoyl or C 1-6 alkoxyformyl, their pharmaceutically acceptable salts, stereoisomers or solvates thereof.