mhurhangee/ep-ind-claims huggingface dataset:
A processor comprising: an instruction unit to receive a first instruction and a second instruction, wherein the first instruction is to extend access permission for a page in a secure processing environment and the second instruction is to restrict access permission for the page; an execution unit to execute the first instruction and the second instruction, wherein execution of the first instruction and the second instruction includes changing at least one of a read, write, and execute access permission in an enclave page cache map entry without setting a modified bit in the enclave page cache map entry, wherein execution of the second instruction includes storing an enclave epoch value in the enclave page cache map entry, and wherein the page is immediately accessible from inside the secure processing environment according to the changed access permission; and a translation lookaside buffer, wherein an operating system is to track enclave threads with translation lookaside buffer entries made stale by the changed access permission and send interprocessor interrupts to trigger enclave thread exits and a translation lookaside buffer shootdown. an instruction unit to receive a first instruction and a second instruction, wherein the first instruction is to extend access permission for a page in a secure processing environment and the second instruction is to restrict access permission for the page; an execution unit to execute the first instruction and the second instruction, wherein execution of the first instruction and the second instruction includes changing at least one of a read, write, and execute access permission in an enclave page cache map entry without setting a modified bit in the enclave page cache map entry, wherein execution of the second instruction includes storing an enclave epoch value in the enclave page cache map entry, and wherein the page is immediately accessible from inside the secure processing environment according to the changed access permission; and a translation lookaside buffer, wherein an operating system is to track enclave threads with translation lookaside buffer entries made stale by the changed access permission and send interprocessor interrupts to trigger enclave thread exits and a translation lookaside buffer shootdown.
A robot cleaner comprising: a main body; a floor detection sensor for detecting a distance from the main body to a floor surface; characterized in that said robot cleaner further comprises a tilt sensor for detecting an inclination of the main body; and a controller for determining whether there is a protruding part that protrudes from a floor surface in a running path of the main body, based on a first sensor value output by the floor detection sensor and a second sensor value output by the tilt sensor. a main body; a floor detection sensor for detecting a distance from the main body to a floor surface; characterized in that said robot cleaner further comprises a tilt sensor for detecting an inclination of the main body; and a controller for determining whether there is a protruding part that protrudes from a floor surface in a running path of the main body, based on a first sensor value output by the floor detection sensor and a second sensor value output by the tilt sensor.
Vehicle with a bodywork comprising a trunk with an upper lid for selectively opening and closing said trunk, the upper lid comprising: - a first element with a first edge (12.1) pivotally attached to a fixed part of the bodywork and a second edge (12.2) opposed to said first edge (12.1); and - a second element with a first edge (14.1) pivotally attached to the second edge (12.2) of the first element; whereby the upper lid comprises at least one retainer (14.5) limiting a pivoting movement of the second element relative to the first element to an angle of not more than 100°, wherein each of the at least one retainer (14.5) comprises a support (14.5.1) attached to the second edge (12.2) of the first element and an arm (14.5.2) pivotally mounted on the support (14.5.1) and extending along an inner face of the second element, said arm being slidable along a guide (14.5.3) on said inner face of said second element and comprising at a distal end means (14.5.2.3) for abutting with said guide (14.5.3), wherein the means (14.5.2.3) for abutting with the guide (14.5.3) is also configured for engaging with said guide so as to hold the second element in a trunk opening position, characterised in that the arm (14.5.2) comprises two longitudinal portions of steel wire (14.5.2.1) progressively converging towards the distal end of the arm and thereafter abruptly diverging and again converging so as to form the means for engaging and abutting (14.5.2.3), the guide (14.5.3) forming a circular groove slidably engaging with the two longitudinal portions of steel wire (14.5.2.1), and able, under application of a longitudinal load, to engage with the means for abutting and engaging (14.5.2.3) by elastically deforming the two longitudinal portions of steel wire (14.5.2.1). - a first element with a first edge (12.1) pivotally attached to a fixed part of the bodywork and a second edge (12.2) opposed to said first edge (12.1); and - a second element with a first edge (14.1) pivotally attached to the second edge (12.2) of the first element;
A modified biotin-binding protein comprising an amino acid sequence having 5 or less amino acid mutations in the amino acid sequence of SEQ ID NO: 2, or an amino acid sequence having an identity of not less than 96% to the amino acid sequence of SEQ ID NO: 2, said modified biotin-binding protein further meeting the following requirements: - an asparagine residue at position 115 of SEQ ID NO: 2 is replaced with cysteine; - the modified biotin-binding protein maintains biotin-binding activity of not less than 75% after a heat treatment at 99.9°C for 30 min compared with that of before the treatment, and - said modified biotin-binding protein is characterized by one or more of the following: (a) four tryptophan residues (W69, W80, W96, and W108) in the amino acid sequence of SEQ ID NO: 2 are not modified or are replaced with phenylalanine, (b) asparagine is not modified or is replaced with glutamine or aspartic acid, (c) aspartic acid is not modified or is replaced with asparagine, serine (S18, S36, or S76) is not modified or is replaced with threonine or tyrosine, (d)tyrosine is not modified or is replaced with serine, threonine, or phenylalanine, (e) threonine is not modified or is replaced with serine or tyrosine, and aspartic acid is not modified or is replaced with glutamic acid or asparagine. - an asparagine residue at position 115 of SEQ ID NO: 2 is replaced with cysteine; - the modified biotin-binding protein maintains biotin-binding activity of not less than 75% after a heat treatment at 99.9°C for 30 min compared with that of before the treatment, and - said modified biotin-binding protein is characterized by one or more of the following: (a) four tryptophan residues (W69, W80, W96, and W108) in the amino acid sequence of SEQ ID NO: 2 are not modified or are replaced with phenylalanine, (b) asparagine is not modified or is replaced with glutamine or aspartic acid, (c) aspartic acid is not modified or is replaced with asparagine, serine (S18, S36, or S76) is not modified or is replaced with threonine or tyrosine, (d)tyrosine is not modified or is replaced with serine, threonine, or phenylalanine, (e) threonine is not modified or is replaced with serine or tyrosine, and aspartic acid is not modified or is replaced with glutamic acid or asparagine. (a) four tryptophan residues (W69, W80, W96, and W108) in the amino acid sequence of SEQ ID NO: 2 are not modified or are replaced with phenylalanine, (b) asparagine is not modified or is replaced with glutamine or aspartic acid, (c) aspartic acid is not modified or is replaced with asparagine, serine (S18, S36, or S76) is not modified or is replaced with threonine or tyrosine, (d)tyrosine is not modified or is replaced with serine, threonine, or phenylalanine, (e) threonine is not modified or is replaced with serine or tyrosine, and aspartic acid is not modified or is replaced with glutamic acid or asparagine.
A method of making the compound which comprises: (a) acylating the compound 10 using to yield the compound 11 and then (b) reacting compound 11 with compound 13 in an activation reaction to produce compound 14 and (c) adding the triazolyl compound 9 in the presence of Cu ion and a ligand to obtain compound 15 and (d) reacting compound 17 with compound 15 to produce compound 18 and (e) conducting a functional group interconversion reaction to yield Compound II above; wherein: R 5 = -H, -OR, -NR 2, -Cl, -Br, -I, -SR; R 6 = -H, -Boc, -Piv, -SO 2 Aryl, -CH 2 SAryl, -CH 2 OP 2, - CH 2 OR, -CH 2 Aryl, -Li, Na, K, Ca, Mg, TMG; R = each independently -H, -C 1 -C 6 alkyl, -aryl, -CH 2 Aryl; X 1 = -H, -Cl, -Br, -I, X 5 = -H, -OR, -NR 2 -Cl, -Br, -I, -SR; X 6 = -H, -OR, -NR 2, -Cl, -Br, -I, -SR, -SO 2 R, -SR 2 +, -OSO 2 R, -OSO 3 R; and X 7 = -Cl, -Br, -I, -OSO 2 R. (a) acylating the compound 10 using to yield the compound 11 and then (b) reacting compound 11 with compound 13 in an activation reaction to produce compound 14 and (c) adding the triazolyl compound 9 in the presence of Cu ion and a ligand to obtain compound 15 and (d) reacting compound 17 with compound 15 to produce compound 18 and (e) conducting a functional group interconversion reaction to yield Compound II above; wherein: R 5 = -H, -OR, -NR 2, -Cl, -Br, -I, -SR; R 6 = -H, -Boc, -Piv, -SO 2 Aryl, -CH 2 SAryl, -CH 2 OP 2, - CH 2 OR, -CH 2 Aryl, -Li, Na, K, Ca, Mg, TMG; R = each independently -H, -C 1 -C 6 alkyl, -aryl, -CH 2 Aryl; X 1 = -H, -Cl, -Br, -I, X 5 = -H, -OR, -NR 2 -Cl, -Br, -I, -SR; X 6 = -H, -OR, -NR 2, -Cl, -Br, -I, -SR, -SO 2 R, -SR 2 +, -OSO 2 R, -OSO 3 R; and X 7 = -Cl, -Br, -I, -OSO 2 R. R 5 = -H, -OR, -NR 2, -Cl, -Br, -I, -SR; R 6 = -H, -Boc, -Piv, -SO 2 Aryl, -CH 2 SAryl, -CH 2 OP 2, - CH 2 OR, -CH 2 Aryl, -Li, Na, K, Ca, Mg, TMG; R = each independently -H, -C 1 -C 6 alkyl, -aryl, -CH 2 Aryl; X 1 = -H, -Cl, -Br, -I, X 5 = -H, -OR, -NR 2 -Cl, -Br, -I, -SR; X 6 = -H, -OR, -NR 2, -Cl, -Br, -I, -SR, -SO 2 R, -SR 2 +, -OSO 2 R, -OSO 3 R; and X 7 = -Cl, -Br, -I, -OSO 2 R.
Biting element for supporting a dynamic imaging examination of a temporomandibular joint of an examination object, comprising a first section, a second section, a coupling unit and at least one sensor, wherein when the biting element is positioned as intended on a jaw region of the examination object, the first section is positioned in a predetermined position relative to an upper jaw of the examination object and the second section is connected mechanically to a lower jaw of the examination object, wherein the first section and the second section are connected mechanically to one another by means of the coupling unit and can be positioned relative to one another as a function of a movement of the temporomandibular joint, and wherein the at least one sensor is embodied to determine an item of information relating to the movement of the temporomandibular joint as a function of the position of the first section relative to the second section, characterised in that the coupling unit is embodied to oppose the movement of the temporomandibular joint by changing a geometric configuration a predetermined resistance, wherein the at least one sensor is embodied to determine the information about the movement of the temporomandibular joint as a function of the geometric configuration of the coupling unit.
An apparatus for preparing food, comprising: - a food preparation chamber; - an air movement device; - a heating device; and - air guiding means; wherein the food preparation chamber is provided by a container structure at least partly enclosing a receiving volume for receiving food to be prepared; wherein the container structure comprises sidewalls, a bottom wall and an upper surface, wherein the bottom wall and/or one of the side walls is air-permeable providing an air entry opening for entering of air into the receiving volume, and wherein the container structure comprises an air discharge opening at the upper surface; wherein the air movement device is a fan with an air inlet and an air outlet; wherein the fan is provided sidewards of the food preparation chamber; and wherein the heating device is configured to heat air of an air flow provided by the air movement device; characterized in that the air guiding means provide an air duct arrangement from the discharge opening via the heating device and the air movement device to the air entry opening; in that the heating device is sidewards of, or above, the food preparation chamber; and in that, during operation of the apparatus, the food is prepared by a through-streaming of hot air, i.e. through delivery of heat to the food by hot air, provided by the air movement device and the heating device. - a food preparation chamber; - an air movement device; - a heating device; and - air guiding means;
Housing for a storage compartment of a vehicle, having a wall with a first surface region which forms a first side of the wall at least partially, and a fastening opening, which is adjacent to the first surface region, wherein, in the fastening opening, a guide means for guiding an opening and/or closing movement of a flap of the storage compartment can be arranged, characterized in that the fastening opening has a lateral surface, which partially projects beyond the first surface region, wherein a further surface region forms a further part of the first side, wherein the first and the further surface regions (12, 17) are separated by a step or merge into one another steplessly by a slope. a wall with a first surface region which forms a first side of the wall at least partially, and a fastening opening, which is adjacent to the first surface region, wherein, in the fastening opening, a guide means for guiding an opening and/or closing movement of a flap of the storage compartment can be arranged, characterized in that the fastening opening has a lateral surface, which partially projects beyond the first surface region, wherein a further surface region forms a further part of the first side, wherein the first and the further surface regions (12, 17) are separated by a step or merge into one another steplessly by a slope.
An apparatus for treating human skin, comprising: an outer housing including a graspable portion and an applicator portion comprising an applicator head; an image capture device configured to capture images of the human skin through an opening in the applicator head; a processor configured to analyse the images of the human skin to identify skin deviations; a replaceable cartridge including at least one nozzle in the applicator portion having a main axis that passes through the opening for delivering a skin treatment composition through the opening in the applicator head onto human skin; and a first roller at a first side of the opening and a second roller at a second, opposite side of the opening, wherein the rollers (64, 66) have surface features (80, 82) for reducing contact between the surface of the rollers (64, 66) and the skin surface. an outer housing including a graspable portion and an applicator portion comprising an applicator head; an image capture device configured to capture images of the human skin through an opening in the applicator head; a processor configured to analyse the images of the human skin to identify skin deviations; a replaceable cartridge including at least one nozzle in the applicator portion having a main axis that passes through the opening for delivering a skin treatment composition through the opening in the applicator head onto human skin; and a first roller at a first side of the opening and a second roller at a second, opposite side of the opening, wherein the rollers (64, 66) have surface features (80, 82) for reducing contact between the surface of the rollers (64, 66) and the skin surface.
A non-therapeutic method for removing leukocytes from a leukocyte-containing liquid to obtain a leukocyte-free liquid comprising passing said leukocyte-containing liquid through a leukocyte removal filter comprising a nonwoven fabric obtained by a melt-blown method having an average fiber diameter of 0.3 to 3.0 μm and having a formation index y of 41 to 50 corresponding to a thickness of 0.3 mm wherein the formation index y is determined as follows: i) preparing a formation tester; ii) setting the total number of pixels using a CCD camera to 3400; iii) providing three sheets of non-woven fabric having the same quality and a uniform thickness of 0.3 mm or less, and measuring the formation index and the thickness of each sheet; iv) placing two of the three sheets of non-woven fabric once upon another so that the thickness is 0.3 mm or more, and measuring the formation index and the thickness, measuring the formation index for all three combinations; v) creating a linear regression equation of the thickness and the formation index, and calculating the formation index at a thickness of 0.3 mm using said equation. i) preparing a formation tester; ii) setting the total number of pixels using a CCD camera to 3400; iii) providing three sheets of non-woven fabric having the same quality and a uniform thickness of 0.3 mm or less, and measuring the formation index and the thickness of each sheet; iv) placing two of the three sheets of non-woven fabric once upon another so that the thickness is 0.3 mm or more, and measuring the formation index and the thickness, measuring the formation index for all three combinations; v) creating a linear regression equation of the thickness and the formation index, and calculating the formation index at a thickness of 0.3 mm using said equation.
An optical transmitter (100; 200; 300; 500), comprising: an encoding means (110; 310; 510) for encoding digital signals to be transmitted under a predetermined transmission condition over an optical carrier wave by using one of a plurality of encoding methods; an encoding control means for selecting a predetermined encoding method corresponding to the predetermined transmission condition from among the plurality of encoding methods and causing the encoding means (110; 310; 510) to operate in accordance with the predetermined encoding method; a mapping means (130; 230; 530) for mapping output bit signals output from the encoding means to modulation symbols; and an optical modulation means for modulating the optical carrier wave based on symbol signals output from the mapping means. an encoding means (110; 310; 510) for encoding digital signals to be transmitted under a predetermined transmission condition over an optical carrier wave by using one of a plurality of encoding methods; an encoding control means for selecting a predetermined encoding method corresponding to the predetermined transmission condition from among the plurality of encoding methods and causing the encoding means (110; 310; 510) to operate in accordance with the predetermined encoding method; a mapping means (130; 230; 530) for mapping output bit signals output from the encoding means to modulation symbols; and an optical modulation means for modulating the optical carrier wave based on symbol signals output from the mapping means.
Any one or more of the following: a cathepsin D polypeptide, a procathepsin D polypeptide, and a polynucleotide encoding a cathepsin D or procathepsin D polypeptide, for use in a method of treating a subject with a synucleinopathy, but not a clinically diagnosed lysosomal storage disease, the method comprising administering to a subject the polypeptide or polynucleotide in an amount effective to reduce a level of α-synuclein in the subject's nervous system, wherein the synucleinopathy comprises any one or more of: Parkinson's disease; sporadic or heritable dementia with Lewy bodies; and Alzheimer's disease of the Lewy body variant. a cathepsin D polypeptide, a procathepsin D polypeptide, and a polynucleotide encoding a cathepsin D or procathepsin D polypeptide,
Catalyst composition comprising an amorphous inorganic porous material with pore diameters of at least 2 nm and containing Al2O3 and SiO2 with an atomic ratio Al/Si > 1, and crystals of molecular sieve, wherein - the crystals of molecular sieve have an maximum diameter not bigger than 50 nm measured using Scanning Electron Microscopy; - the catalyst composition presents a concentration of acid sites ranging from 50 to 1200 μmol/g measured by Temperature-Programmed Desorption of ammonia, TPD NH3 in accordance to the measurement protocol indicated in the description; and - a powder X ray diffraction pattern of said catalyst composition obtained using Cu Kα radiation is the same as the X ray diffraction pattern of said inorganic porous material, i.e. it does not present the characteristic X ray bands of the molecular sieve - the catalyst composition contains a Bronsted acidic sites concentration of at least 10 μmol/g measured by pyridine desorption at 150°C quantified via Infrared Spectroscopy in accordance to the measurement protocol indicated in the description - the catalyst composition contains up to 30 weight % of crystals of molecular sieve relative to the total weight of the catalyst composition - the catalyst composition has a surface area of at least 250 m2/g, measured using ASTM D3663; - the catalyst composition has a ratio V total / Vmicro of at least 5 with V total standing for the total porous volume of the catalyst compositions and Vmicro standing for the microporous volume of the catalyst compositions both being measured via ASTM D4365. - the crystals of molecular sieve have an maximum diameter not bigger than 50 nm measured using Scanning Electron Microscopy; - the catalyst composition presents a concentration of acid sites ranging from 50 to 1200 μmol/g measured by Temperature-Programmed Desorption of ammonia, TPD NH3 in accordance to the measurement protocol indicated in the description; and - a powder X ray diffraction pattern of said catalyst composition obtained using Cu Kα radiation is the same as the X ray diffraction pattern of said inorganic porous material, i.e. it does not present the characteristic X ray bands of the molecular sieve - the catalyst composition contains a Bronsted acidic sites concentration of at least 10 μmol/g measured by pyridine desorption at 150°C quantified via Infrared Spectroscopy in accordance to the measurement protocol indicated in the description - the catalyst composition contains up to 30 weight % of crystals of molecular sieve relative to the total weight of the catalyst composition - the catalyst composition has a surface area of at least 250 m2/g, measured using ASTM D3663; - the catalyst composition has a ratio V total / Vmicro of at least 5 with V total standing for the total porous volume of the catalyst compositions and Vmicro standing for the microporous volume of the catalyst compositions both being measured via ASTM D4365.
A composite lay up comprising a plurality of layers arranged in a stacked formation, at least one of said plurality of layers comprising a plurality of macro fibers in a side-by-side arrangement, said macro fibers comprising: a plurality of inner fibers each having an inner fiber final cross-sectional size of less than approximately 100 nanometers; and the inner fibers being surrounded by matrix material, wherein the macro fiber comprises upper and lower surfaces that are substantially planar and parallel. a plurality of inner fibers each having an inner fiber final cross-sectional size of less than approximately 100 nanometers; and the inner fibers being surrounded by matrix material,