A compound of Formula I: or a pharmaceutically acceptable salt thereof wherein, R 1 is selected from the group consisting of of: R 11 is H, halogen, alkyl or alkoxy, all alkyl and alkoxy groups optionally being substituted with one or more halogen; R 12 is halogen, alkyl alkenyl, alkynyl, alkoxy, cycloalkyl, or cyano, all alkyl, alkoxy and cycloalkyl groups optionally being substituted with one or more halogen; R 13 is H, halogen, alkyl or alkoxy, all alkyl and alkoxy groups optionally being substituted with one or more halogen; R 14 is H, halogen, alkyl or alkoxy, all alkyl and alkoxy groups optionally being substituted with one or more halogen; R 15 is H, halogen, alkyl or alkoxy, all alkyl and alkoxy groups optionally being substituted with one or more halogen; R 2 is selected from the group consisting of: a) hydrogen, b) alkyl, wherein alkyl optionally can be substituted, R 3 is selected from the group consisting of: a) aryl, b) heteroaryl, c) cycloalkyl, d) heterocycloalkyl, e) alkyl, f) alkylamino, g) cycloalkylamino h) arylamino, i) heteroarylamino, j) heterocycloalkylamino, wherein all groups optionally can be substituted, R 4 is selected from the group consisting of: a) hydrogen, b) alkyl, wherein alkyl optionally can be substituted, R 5 is selected from the group consisting of: a) hydrogen, b) alkyl, wherein alkyl optionally can be substituted, A is selected from CH(R a), C, S or SO 2, R a is selected from the group consisting of: a) hydrogen, b) alkyl, wherein alkyl optionally can be substituted with fluorine or hydroxyl. R 1 is selected from the group consisting of of: R 11 is H, halogen, alkyl or alkoxy, all alkyl and alkoxy groups optionally being substituted with one or more halogen; R 12 is halogen, alkyl alkenyl, alkynyl, alkoxy, cycloalkyl, or cyano, all alkyl, alkoxy and cycloalkyl groups optionally being substituted with one or more halogen; R 13 is H, halogen, alkyl or alkoxy, all alkyl and alkoxy groups optionally being substituted with one or more halogen; R 14 is H, halogen, alkyl or alkoxy, all alkyl and alkoxy groups optionally being substituted with one or more halogen; R 15 is H, halogen, alkyl or alkoxy, all alkyl and alkoxy groups optionally being substituted with one or more halogen; R 2 is selected from the group consisting of: a) hydrogen, b) alkyl, a) hydrogen, b) alkyl, wherein alkyl optionally can be substituted, R 3 is selected from the group consisting of: a) aryl, b) heteroaryl, c) cycloalkyl, d) heterocycloalkyl, e) alkyl, f) alkylamino, g) cycloalkylamino h) arylamino, i) heteroarylamino, j) heterocycloalkylamino, a) aryl, b) heteroaryl, c) cycloalkyl, d) heterocycloalkyl, e) alkyl, f) alkylamino, g) cycloalkylamino h) arylamino, i) heteroarylamino, j) heterocycloalkylamino, wherein all groups optionally can be substituted, R 4 is selected from the group consisting of: a) hydrogen, b) alkyl, a) hydrogen, b) alkyl, wherein alkyl optionally can be substituted, R 5 is selected from the group consisting of: a) hydrogen, b) alkyl, a) hydrogen, b) alkyl, wherein alkyl optionally can be substituted, A is selected from CH(R a), C, S or SO 2, R a is selected from the group consisting of: a) hydrogen, b) alkyl, a) hydrogen, b) alkyl, wherein alkyl optionally can be substituted with fluorine or hydroxyl.