A deflecting guide catheter for guiding a medical device through a lumen of a patient during a medical procedure comprising: an elongated tubular body portion having a lumen and a distal end and proximal end; a first anchor band near the distal end of the elongated tubular body portion; a second anchor band near the distal end of the elongated tubular body portion; a handle assembly attached to the proximal end of the elongated tubular body portion wherein the handle assembly comprises a proximal actuator assembly; a first puller wire connected from the proximal actuator assembly to the first anchor band wherein movement of the actuator assembly in a proximal direction causes proximal movement of the puller wire and deflection of the distal end of the deflecting guide catheter; and a second puller wire connected from the distal actuator assembly to the second anchor band wherein movement of the distal actuator assembly in a proximal direction causes proximal movement of the second puller wire and deflection of the distal end of the deflecting guide catheter, wherein: the elongated tubular body portion is comprised of polymeric materials having two different durometers used in an pattern with a first material used in two circumferential portions opposite one another and a second material used in two other opposing circumferential portions; the durometer of the first material is greater than the durometer of the second material; and the first puller wire is attached to the first anchor band at a position in the first material and the second puller wire is attached to a second anchor band at a position in the second material. an elongated tubular body portion having a lumen and a distal end and proximal end; a first anchor band near the distal end of the elongated tubular body portion; a second anchor band near the distal end of the elongated tubular body portion; a handle assembly attached to the proximal end of the elongated tubular body portion wherein the handle assembly comprises a proximal actuator assembly; a first puller wire connected from the proximal actuator assembly to the first anchor band wherein movement of the actuator assembly in a proximal direction causes proximal movement of the puller wire and deflection of the distal end of the deflecting guide catheter; and a second puller wire connected from the distal actuator assembly to the second anchor band wherein movement of the distal actuator assembly in a proximal direction causes proximal movement of the second puller wire and deflection of the distal end of the deflecting guide catheter, wherein: the elongated tubular body portion is comprised of polymeric materials having two different durometers used in an pattern with a first material used in two circumferential portions opposite one another and a second material used in two other opposing circumferential portions; the durometer of the first material is greater than the durometer of the second material; and the first puller wire is attached to the first anchor band at a position in the first material and the second puller wire is attached to a second anchor band at a position in the second material. the elongated tubular body portion is comprised of polymeric materials having two different durometers used in an pattern with a first material used in two circumferential portions opposite one another and a second material used in two other opposing circumferential portions; the durometer of the first material is greater than the durometer of the second material; and the first puller wire is attached to the first anchor band at a position in the first material and the second puller wire is attached to a second anchor band at a position in the second material.