mhurhangee/ep-ind-claims huggingface dataset:
An isolated bi-specific antigen-binding polypeptide devoid of antibody light chains comprising an antibody heavy chain comprising a first VH domain that specifically binds to a first antigen, C-terminally linked to a second VH domain that specifically binds to a second antigen, wherein the first and second antigen are independently selected from the group consisting of human PDGFRβ and HER2, wherein one of the first VH domain or the second VH domain binds specifically to human HER2 and comprises HCDR3, HCDR2 and HCDR1 amino acid sequences selected from the group consisting of SEQ ID NO: 1, 2 and 3; 4, 5 and 6; 7, 8 and 9; and 10, 11 and 12, and wherein the polypeptide devoid of antibody light chains specifically binds to PDGFRβ and HER2.
Laundry drum for a laundry dryer, wherein the laundry drum has a drum interior space for receiving laundry to be dried and comprises a wall, wherein the drum interior space is separated by the wall from a drum exterior space, wherein the wall has a plurality of air openings through which a process air stream is guidable from the drum exterior space into the drum interior space, wherein the wall is at least partially made from perforated sheet metal, wherein the wall has collars directed into the drum exterior space and revolving around the air openings, characterized in that an intermediate volume between at least two of the collars is filled with a material in the drum exterior space at least up to an extension of the collars into the drum exterior space such that the wall has a flat or convex surface facing the drum exterior space at least between two of the air openings.
A process for electroless plating a metal on a non-conductive surface comprising; a) preparing a colloidal catalyst solution comprising silver ions and a polymer polymerized from monomers comprising at least a monomer having two or more carboxyl groups or carboxylic acid salt groups and an oxygen atom as an ether bond in a principal chain, wherein said polymer is chosen from polyepoxysuccinic acid, poly[oxy[1-carboxy-1-(carboxymethyl)-1,2-ethanediyl]] and a copolymer of phosphonic acid and epoxysuccinic acid; then b) adding a reducing agent in said solution with stirring to form a colloidal catalyst of silver nanoparticles stabilized by the polymer; c) dipping a substrate to be plated into a solution of the colloidal catalyst; and d) conducting electroless plating of the substrate without an accelerating step. a) preparing a colloidal catalyst solution comprising silver ions and a polymer polymerized from monomers comprising at least a monomer having two or more carboxyl groups or carboxylic acid salt groups and an oxygen atom as an ether bond in a principal chain, wherein said polymer is chosen from polyepoxysuccinic acid, poly[oxy[1-carboxy-1-(carboxymethyl)-1,2-ethanediyl]] and a copolymer of phosphonic acid and epoxysuccinic acid; then b) adding a reducing agent in said solution with stirring to form a colloidal catalyst of silver nanoparticles stabilized by the polymer; c) dipping a substrate to be plated into a solution of the colloidal catalyst; and d) conducting electroless plating of the substrate without an accelerating step.
Apparatus for the processing of a material web, with an ultrasonic unit containing a converter, a booster and a sonotrode, and a mating tool, wherein the material web is guided through a gap between the sonotrode and the mating tool and is processed by the sonotrode, wherein the ultrasonic unit may be adjusted relative to the mating tool via a traversable slide, and wherein there is provided a support which acts on at least one side face of the sonotrode and guides the sonotrode in its longitudinal direction, characterised in that not the sonotrode but instead the booster is permanently connected to the slide and wherein the support has a coefficient of thermal expansion which is less than 10 -5 /K and is fixed in or on the slide, so that the support is force-neutral relative to the sonotrode and does not initiate in the sonotrode any forces acting in the longitudinal direction of the sonotrode.
A sclerosing agent for use in promoting diffuse pleurodesis in a patient, wherein the sclerosing agent is administered to the patient using a catheter comprising: a proximal end; a distal end; and the sclerosing agent proximal to the distal end, wherein the sclerosing agent is configured to promote inflammation or fibrosis of a pleural layer; by inserting the distal end of the catheter into a pleural space between a first pleural layer and a second pleural layer of the patient such that the catheter terminates in the patient's pleural space and such that the sclerosing agent is brought into contact with the pleural space; sustainably releasing the sclerosing agent into the pleural space over a period of time greater than or equal to twenty-four hours; and creating a diffuse pleurodesis of the first and second pleural layers. a proximal end; a distal end; and the sclerosing agent proximal to the distal end, wherein the sclerosing agent is configured to promote inflammation or fibrosis of a pleural layer;
Toilet seat or toilet lid implemented with at least one functional electronic or electric component mounted on a support which is joint to a base material of the toilet seat or the toilet lid and is connected to a power supply or signal processing unit, wherein the support consists of approximately the same material as a base body of the toilet seat or toilet lid, wherein the arrangement of the toilet seat or toilet lid is prefabricated in a separate production line and then delivered to a press as a preform, and wherein a seat heater is mounted on the prefabricated support as an additional functional, preferably electronic or electric component.
A telesurgical system for performing surgery on a patient, the system comprising: a support structure (110, 850) for receiving, at a connector of the support structure (110, 850), one manipulator (500, 700, 720, 740) of a plurality of different manipulators (500, 700, 720, 740) each having a plurality of degrees of freedom; a controller (852, 862); and a hardware mapping unit configured to implement a plurality of maps (1200, 1250), each map (1200, 1250) being configured to map signals from input elements (854, 910, 920) of the connector to interface elements of the controller (852, 862), wherein the maps (1200, 1250) include a specific map (1200, 1250) for each of the different manipulators (500, 700, 720, 740), wherein a first map (940, 950) of the maps (1200, 1250) maps a first input element to a first interface element when a first manipulator (500, 700, 720, 740) of the plurality of different manipulators is connected to the connector and a second map (941, 951) of the maps (1200, 1250) maps the first input element to a second interface element when a second manipulator (500, 700, 720, 740) of the plurality of different manipulators is connected to the connector in place of the first manipulator (500, 700, 720, 740). a support structure (110, 850) for receiving, at a connector of the support structure (110, 850), one manipulator (500, 700, 720, 740) of a plurality of different manipulators (500, 700, 720, 740) each having a plurality of degrees of freedom; a controller (852, 862); and a hardware mapping unit configured to implement a plurality of maps (1200, 1250), each map (1200, 1250) being configured to map signals from input elements (854, 910, 920) of the connector to interface elements of the controller (852, 862), wherein the maps (1200, 1250) include a specific map (1200, 1250) for each of the different manipulators (500, 700, 720, 740), wherein a first map (940, 950) of the maps (1200, 1250) maps a first input element to a first interface element when a first manipulator (500, 700, 720, 740) of the plurality of different manipulators is connected to the connector and a second map (941, 951) of the maps (1200, 1250) maps the first input element to a second interface element when a second manipulator (500, 700, 720, 740) of the plurality of different manipulators is connected to the connector in place of the first manipulator (500, 700, 720, 740).
A system for a lithographic apparatus wherein the lithographic apparatus comprises: a housing comprising an internal wall; a radiation-receiving component (10, 11; 13, 14; MA; W) arranged within a chamber defined at least in part by the internal wall and configured to receive a radiation beam; wherein the system comprises: a cooling apparatus arranged to cool at least a portion of the internal wall to a temperature below that of the radiation-receiving component such that during use of the cooling apparatus a contaminant within the chamber rests preferentially on the internal wall relative to the radiation-receiving component, and wherein the system is configured such that, prior to an exposure operation of the lithographic apparatus, heating of the radiation-receiving component is controlled to increase a temperature difference between the radiation-receiving component and the at least a portion of the internal wall. a housing comprising an internal wall; a radiation-receiving component (10, 11; 13, 14; MA; W) arranged within a chamber defined at least in part by the internal wall and configured to receive a radiation beam; wherein the system comprises: a cooling apparatus arranged to cool at least a portion of the internal wall to a temperature below that of the radiation-receiving component such that during use of the cooling apparatus a contaminant within the chamber rests preferentially on the internal wall relative to the radiation-receiving component, and wherein the system is configured such that, prior to an exposure operation of the lithographic apparatus, heating of the radiation-receiving component is controlled to increase a temperature difference between the radiation-receiving component and the at least a portion of the internal wall. a cooling apparatus arranged to cool at least a portion of the internal wall to a temperature below that of the radiation-receiving component such that during use of the cooling apparatus a contaminant within the chamber rests preferentially on the internal wall relative to the radiation-receiving component, and wherein the system is configured such that, prior to an exposure operation of the lithographic apparatus, heating of the radiation-receiving component is controlled to increase a temperature difference between the radiation-receiving component and the at least a portion of the internal wall.
Dispensing mechanism for dispensing measurement strips, comprising: - a strip cartridge with an enclosure for retaining a plurality of measurement strips and a dispensing slot for dispensing one measurement strip at a time, - a spring rotatably arranged with respect to the strip cartridge, the spring comprising at least one engagement section (11.1) adapted to engage one of the measurement strips at a time and move it out of the dispensing slot when the spring is rotated, - a guide slot arranged in the strip cartridge for guiding the engagement section (11.1) of the spring as the spring is rotated wherein the guide slot comprises a first section (12.1) in parallel to and in the vicinity of the measurement strips such that the engagement section (11.1) engages one of the blood glucose measurement strips when within the first section (12.1), wherein the first section (12.1) is followed by a second section (12.2) directed to allow the engagement section (11.1) to move out of engagement with the measurement strips, characterized in that the second section points in an outward direction and (12.2) is substantially transversally arranged to the first section (12.1) so as to allow the engagement section (11.1) to relax and move away and out of engagement with the measurement strips and so as to provide a one-way feature preventing rotation of the spring against a rotational direction. - a strip cartridge with an enclosure for retaining a plurality of measurement strips and a dispensing slot for dispensing one measurement strip at a time, - a spring rotatably arranged with respect to the strip cartridge, the spring comprising at least one engagement section (11.1) adapted to engage one of the measurement strips at a time and move it out of the dispensing slot when the spring is rotated, - a guide slot arranged in the strip cartridge for guiding the engagement section (11.1) of the spring as the spring is rotated wherein the guide slot comprises a first section (12.1) in parallel to and in the vicinity of the measurement strips such that the engagement section (11.1) engages one of the blood glucose measurement strips when within the first section (12.1), wherein the first section (12.1) is followed by a second section (12.2) directed to allow the engagement section (11.1) to move out of engagement with the measurement strips, characterized in that the second section points in an outward direction and (12.2) is substantially transversally arranged to the first section (12.1) so as to allow the engagement section (11.1) to relax and move away and out of engagement with the measurement strips and so as to provide a one-way feature preventing rotation of the spring against a rotational direction.
A mandolin slicer comprising: a handle having a first end and a second end; a frame extending from the first end of the handle and having two opposite side walls; a guiding plate having a proximal end pivotally connected to the frame, and a distal end; a slicing plate held between the two side walls of the frame and configured to comprise a slicing blade, wherein the slicing blade and the distal end of the guiding plate together define a gap as slice thickness for an item to be sliced; a linkage for movably carrying the guiding plate so that the movement of the linkage enables the guiding plate to pivot around its proximal end relative to the slicing blade thereby to provide variable slice thickness for the item to be sliced; and an actuator assembly in operative connection with the linkage to move the linkage relative to the guiding plate characterised in that the actuator assembly is configured as a ballpoint pen ratchet mechanism provided in the handle, the ballpoint pen ratchet mechanism being latched in a plurality of latched positions, which are respectively correspondent to the plurality of carrying positions of the linkage. a handle having a first end and a second end; a frame extending from the first end of the handle and having two opposite side walls; a guiding plate having a proximal end pivotally connected to the frame, and a distal end; a slicing plate held between the two side walls of the frame and configured to comprise a slicing blade, wherein the slicing blade and the distal end of the guiding plate together define a gap as slice thickness for an item to be sliced; a linkage for movably carrying the guiding plate so that the movement of the linkage enables the guiding plate to pivot around its proximal end relative to the slicing blade thereby to provide variable slice thickness for the item to be sliced; and an actuator assembly in operative connection with the linkage to move the linkage relative to the guiding plate characterised in that the actuator assembly is configured as a ballpoint pen ratchet mechanism provided in the handle, the ballpoint pen ratchet mechanism being latched in a plurality of latched positions, which are respectively correspondent to the plurality of carrying positions of the linkage.
A compound which is Ac-Arg-c(Cys-D-Ala-His-D-Phe-Arg-Trp-Cys)-NH 2 (SEQ ID NO: 50) or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising a therapeutically effective amount of the compound and a pharmaceutically acceptable carrier or diluent, for use in therapy.
A booster comprising: a booster circuit configured to generate a boosted output obtained by boosting an input voltage as a target to be boosted; an auxiliary booster circuit configured to generate start-up energy necessary for starting up the booster circuit, based on the input voltage; a power storing unit configured to store all or a part of the boosted output; and a selector circuit configured to output, to the booster circuit, either one of the start-up energy output from the auxiliary booster circuit and start-up energy output from the power storing unit; and wherein the booster circuit is configured to feed back a part of the boosted output, as operation energy, to the booster circuit itself, and control the start-up of the auxiliary booster circuit and the start-up of the power storing unit respectively based on the boosted output. a booster circuit configured to generate a boosted output obtained by boosting an input voltage as a target to be boosted; an auxiliary booster circuit configured to generate start-up energy necessary for starting up the booster circuit, based on the input voltage; a power storing unit configured to store all or a part of the boosted output; and a selector circuit configured to output, to the booster circuit, either one of the start-up energy output from the auxiliary booster circuit and start-up energy output from the power storing unit; and wherein the booster circuit is configured to feed back a part of the boosted output, as operation energy, to the booster circuit itself, and control the start-up of the auxiliary booster circuit and the start-up of the power storing unit respectively based on the boosted output.
Connection terminal for electrically contact-connecting at least one conductor to a current bar which is mounted on a holder, comprising at least one clamping spring with a first limb and a second limb, wherein the clamping spring is provided for applying a clamping force for clamping the conductor, wherein an operating device which comprises the clamping spring is provided, characterized in that an insert device is arranged between the first limb and the second limb of the clamping spring which is designed as a tension spring, which insert device provides a mating bearing for a tool when the operating device is operated.
A flashlight comprising - a casing having a casing interior and a casing outer side, - an infrared light source arranged in the casing interior for operation in at least one infrared light mode, - a visible light source arranged in the casing interior for operation in at least one visible light mode, - an energy source, - a control unit for driving the infrared light source and the visible light source, and - a manually operable operating element, arranged on the casing outer side, for selecting between the at least one infrared light mode, the at least one visible light mode and a switch-off mode; wherein - the operating element is movable into different adjustment positions along an adjustment path comprising a first adjustment range and a second adjustment range, wherein, in said first range, the at least one infrared light mode or the switch-off mode is selectable and, in said second range, the at least one visible light mode is selectable; - a locking element for locking the operating element upon its movement from said first range to said second range; and - wherein the locking state of the operating element upon its movement from said first range to said second range can be released by actuation of the locking element in the switched-off mode adjustment position; characterized in that - a transition of the operating element from said second range to said first range is performed in an unhindered manner. - a casing having a casing interior and a casing outer side, - an infrared light source arranged in the casing interior for operation in at least one infrared light mode, - a visible light source arranged in the casing interior for operation in at least one visible light mode, - an energy source, - a control unit for driving the infrared light source and the visible light source, and - a manually operable operating element, arranged on the casing outer side, for selecting between the at least one infrared light mode, the at least one visible light mode and a switch-off mode; wherein - the operating element is movable into different adjustment positions along an adjustment path comprising a first adjustment range and a second adjustment range, wherein, in said first range, the at least one infrared light mode or the switch-off mode is selectable and, in said second range, the at least one visible light mode is selectable; - a locking element for locking the operating element upon its movement from said first range to said second range; and - wherein the locking state of the operating element upon its movement from said first range to said second range can be released by actuation of the locking element in the switched-off mode adjustment position; - a transition of the operating element from said second range to said first range is performed in an unhindered manner.
Method for processing board-shaped products of wood or wood substitutes, in which the board-shaped product is fitted in the region of a narrow side with an electric or electronic component comprising an individualising code, wherein for this purpose a recess is formed on the narrow side wherein the component is arranged on, against or in a carrier material which is inserted into the recess, characterised in that after inserting the carrier material an edge processing is carried out along the narrow side.
Double fabric comprising an upper fabric G H and a lower fabric G L, wherein the fabrics G H and G L each comprise a plurality of warp threads K, K R, K H and K L and a plurality of weft threads S, S H and S L and the fabrics G H and G L are woven with the warp threads K R in the end region of the weft threads S to a common edge R, R', wherein between the two edges R and R' the upper fabric G H is divided into a segment A H and a segment B H, wherein the lower fabric G L is divided into a segment A L and a segment B L as a mirror images to the segments A H and B H, wherein - the segment A H has the same length as the segment B L and the segment A L has the same length as the segment B H and - at least one weft thread S connects the segment A H of the upper fabric G H to the segment B L of the lower fabric G L and thus forms the weft thread S(A H B L) and at least one weft thread S connects the segment A L of the lower fabric G L to the segment B H of the upper fabric G H and thus forms the weft thread S(A L B H), wherein the weft thread S(A H B L) is preferably arranged parallel to the segment B H and the weft thread S(A L B H) is preferably arranged parallel to the segment A H, characterized in that the weft threads S H are woven with the warp threads K H to the upper fabric G H and extend from the edge R along the entire upper fabric G H, which comprises the warp threads K H as far as the edge R' and that the weft threads S L are woven with the warp threads K L to the lower fabric G L and extend from the edge R along the entire lower fabric G L comprising the warp threads K L as far as the edge R'. - the segment A H has the same length as the segment B L and the segment A L has the same length as the segment B H and - at least one weft thread S connects the segment A H of the upper fabric G H to the segment B L of the lower fabric G L and thus forms the weft thread S(A H B L) and at least one weft thread S connects the segment A L of the lower fabric G L to the segment B H of the upper fabric G H and thus forms the weft thread S(A L B H), wherein the weft thread S(A H B L) is preferably arranged parallel to the segment B H and the weft thread S(A L B H) is preferably arranged parallel to the segment A H,