An analyte measurement system comprising: a biosensor having a plurality of electrodes including at least two electrodes with an enzyme disposed thereon; and a meter including: a temperature sensor, and a microcontroller coupled to a power source, memory and the plurality of electrodes of the biosensor and in which the microcontroller is configured to: measure ambient temperature proximate the biosensor; drive a signal to the at least two electrodes when a fluid sample with an analyte is deposited proximate the at least two electrodes; measure a signal output from the at least two electrodes during the electrochemical reaction; calculate an uncompensated analyte value from the signal output; characterized in that the microcontroller is configured to: adjust the uncompensated analyte value to a final analyte value with a temperature compensation term defined by an equation of the following form: G F = G 0 1 + x 1 T − T 0 3 + x 2 T − T 0 2 + x 3 T − T 0 x 4 log G 0 3 + x 5 log G 0 2 + x 6 log G 0 + 1 Where: G F comprises the final analyte value G 0 comprises the uncompensated analyte value ≥1; T comprises the temperature measured by the meter (in °C); T 0 comprises 22°C; x 1 comprises 4.69e-4, x 2 comprises -2.19e-2, x 3 comprises 2.80e-1, x 4 comprises 2.99e0, x 5 comprises -3.89e1, and x 6 comprises 1.32e 2; and annunciate the final analyte value. a biosensor having a plurality of electrodes including at least two electrodes with an enzyme disposed thereon; and a meter including: a temperature sensor, and a microcontroller coupled to a power source, memory and the plurality of electrodes of the biosensor and in which the microcontroller is configured to: measure ambient temperature proximate the biosensor; drive a signal to the at least two electrodes when a fluid sample with an analyte is deposited proximate the at least two electrodes; measure a signal output from the at least two electrodes during the electrochemical reaction; calculate an uncompensated analyte value from the signal output; characterized in that the microcontroller is configured to: adjust the uncompensated analyte value to a final analyte value with a temperature compensation term defined by an equation of the following form: G F = G 0 1 + x 1 T − T 0 3 + x 2 T − T 0 2 + x 3 T − T 0 x 4 log G 0 3 + x 5 log G 0 2 + x 6 log G 0 + 1 Where: G F comprises the final analyte value G 0 comprises the uncompensated analyte value ≥1; T comprises the temperature measured by the meter (in °C); T 0 comprises 22°C; x 1 comprises 4.69e-4, x 2 comprises -2.19e-2, x 3 comprises 2.80e-1, x 4 comprises 2.99e0, x 5 comprises -3.89e1, and x 6 comprises 1.32e 2; and annunciate the final analyte value. a temperature sensor, and a microcontroller coupled to a power source, memory and the plurality of electrodes of the biosensor and in which the microcontroller is configured to: measure ambient temperature proximate the biosensor; drive a signal to the at least two electrodes when a fluid sample with an analyte is deposited proximate the at least two electrodes; measure a signal output from the at least two electrodes during the electrochemical reaction; calculate an uncompensated analyte value from the signal output; characterized in that the microcontroller is configured to: adjust the uncompensated analyte value to a final analyte value with a temperature compensation term defined by an equation of the following form: G F = G 0 1 + x 1 T − T 0 3 + x 2 T − T 0 2 + x 3 T − T 0 x 4 log G 0 3 + x 5 log G 0 2 + x 6 log G 0 + 1 Where: G F comprises the final analyte value G 0 comprises the uncompensated analyte value ≥1; T comprises the temperature measured by the meter (in °C); T 0 comprises 22°C; x 1 comprises 4.69e-4, x 2 comprises -2.19e-2, x 3 comprises 2.80e-1, x 4 comprises 2.99e0, x 5 comprises -3.89e1, and x 6 comprises 1.32e 2; and annunciate the final analyte value. measure ambient temperature proximate the biosensor; drive a signal to the at least two electrodes when a fluid sample with an analyte is deposited proximate the at least two electrodes; measure a signal output from the at least two electrodes during the electrochemical reaction; calculate an uncompensated analyte value from the signal output; characterized in that the microcontroller is configured to: adjust the uncompensated analyte value to a final analyte value with a temperature compensation term defined by an equation of the following form: G F = G 0 1 + x 1 T − T 0 3 + x 2 T − T 0 2 + x 3 T − T 0 x 4 log G 0 3 + x 5 log G 0 2 + x 6 log G 0 + 1 Where: G F comprises the final analyte value G 0 comprises the uncompensated analyte value ≥1; T comprises the temperature measured by the meter (in °C); T 0 comprises 22°C; x 1 comprises 4.69e-4, x 2 comprises -2.19e-2, x 3 comprises 2.80e-1, x 4 comprises 2.99e0, x 5 comprises -3.89e1, and x 6 comprises 1.32e 2; and annunciate the final analyte value. G F comprises the final analyte value G 0 comprises the uncompensated analyte value ≥1; T comprises the temperature measured by the meter (in °C); T 0 comprises 22°C; x 1 comprises 4.69e-4, x 2 comprises -2.19e-2, x 3 comprises 2.80e-1, x 4 comprises 2.99e0, x 5 comprises -3.89e1, and x 6 comprises 1.32e 2;