mhurhangee/ep-ind-claims huggingface dataset:
A compound or a pharmaceutically acceptable salt thereof, said compound described by the formula: wherein R 2 is selected from the group consisting of H, alkyl, and substituted alkyl; wherein R 3 is selected from the group consisting of H, alkyl, halogen, and OH; wherein R 4 is selected from the group consisting of C and N; wherein R 5 is selected from the group consisting of H, alkyl, substituted alkyl, mono-substituted aryl, di-substituted aryl, and tri-substituted aryl; wherein R 6 is selected from the group consisting of C and N; wherein R 11, R 12, R 13, and R 14, are independently selected from the group consisting of H, alkyl, fluoroalkyl, and wherein R 15, R 16, R 17, and R 18 are independently selected from the group consisting of C and N; wherein R 19 is a ketone; wherein R 20 is a ketone; and wherein R 21, R 22, R 23, and R 24 are independently selected from the group consisting of H, halogen, OH, fluoroalkyl, sulfonamide, sulfone, OCH 3, CH 3, SO 2 R 7', SO 2 N(R 7') 2, OR 7', N(R 7') 2, CON(R 7') 2, NHCOR 7', NHSO 2 R 7', alkyl, mono-substituted alkyl, di-substituted alkyl, tri-substituted alkyl; wherein R 7' is selected from the group consisting of halogen, H, alkyl, mono-substituted alkyl, di-substituted alkyl, tri-substituted alkyl, aryl, mono-substituted aryl, di-substituted aryl, tri-substituted aryl, cycloalipathic, mono-substituted cycloalipathic, di-substituted cycloalipathic, and tri-substituted cycloalipathic; wherein no more than two of R 21, R 22, R 23 and R 24 can be hydrogen; wherein the stereochemical configuration at a stereocenter in said compound is R, S, or a mixture thereof; wherein aliphatic is selected from the group consisting of alkyl, alkenyl, and alkynyl; wherein substituted is where at least one of the hydrogen atoms has been replaced by a halogen, an amino, a hydroxy, a nitro, a thio, a ketone, an aldehyde, an ether, an ester, an amide, a sulfone, a sulfonamide, a lower aliphatic or a ring (aryl or cycloaliphatic).
A measurement system, comprising: a container configured to contain solvated target molecules; and a plurality of magnetoresistive, MR, sensor devices (122, 322), each of the MR sensor devices comprising at least one MR sensor disposed near the container and configured to measure a magnetic field generated by the solvated target molecules, each of the at least one MR sensor comprising a pin layer having a pinned direction of magnetization, a free layer having a direction of magnetization that varies with an applied magnetic field, and a non-conductive layer separating the pin layer and the free layer, characterized in that the MR sensor devices are arranged along at least three orthogonal directions with respect to the container. a container configured to contain solvated target molecules; and a plurality of magnetoresistive, MR, sensor devices (122, 322), each of the MR sensor devices comprising at least one MR sensor disposed near the container and configured to measure a magnetic field generated by the solvated target molecules, each of the at least one MR sensor comprising a pin layer having a pinned direction of magnetization, a free layer having a direction of magnetization that varies with an applied magnetic field, and a non-conductive layer separating the pin layer and the free layer, characterized in that the MR
Arrangement for detecting an operational state of a strip guide, particularly a slab plant or thin-slab plant, comprising at least one strip guide segment with rollers and/or sub-rollers, which are mounted by means of bearings, wherein measured value pick-ups for monitoring bearing forces and/or change over time of bearing forces are arranged at least at individual bearings, characterised in that an evaluating unit for detecting an operational state is provided, wherein the data detected by the measured value pick-ups are supplied to the evaluating unit for evaluation and/or signalling the operational state of the plant, at least one segment and/or at least one roller and/or at least one sub-roller, wherein the evaluated data are used for monitoring roller fracture and/or for evaluating roller slip.
A method of controlling an autonomous vehicle, the method comprising: acquiring a vehicle state configuration information from a cloud; enabling a task receiving function of the vehicle, in response to the vehicle state configuration information indicating that the vehicle is in an automatic operation state; acquiring a task information from the cloud in response to the task receiving function being enabled; and controlling the vehicle according to the task information. acquiring a vehicle state configuration information from a cloud; enabling a task receiving function of the vehicle, in response to the vehicle state configuration information indicating that the vehicle is in an automatic operation state; acquiring a task information from the cloud in response to the task receiving function being enabled; and controlling the vehicle according to the task information.
A radar transceiver, comprising: a chirp generator for generating a chirp having an initial frequency, f 0, a final frequency, f 1 a controllable variable gain amplifier having an input connected to an output of the chirp generator, a control unit connected to a control input on the chirp generator, and to a control input on the controllable variable gain amplifier, said control unit adapted to output a first control signal to the chirp generator such that the chirp generator starts generating the chirp, output a second control signal to the controllable variable gain amplifier such that the controllable variable gain amplifier starts increasing an amplification in the controllable variable gain amplifier from a first amplification level, A 1, along a slope, to a second amplification level, A 2, during at least a portion of a time interval during which the chirp is generated, wherein the control unit is adapted to output the first control signal and the second control signal such that the start of generating the chirp coincides with the start of the increase in amplification. a chirp generator for generating a chirp having an initial frequency, f 0, a final frequency, f 1 a controllable variable gain amplifier having an input connected to an output of the chirp generator, a control unit connected to a control input on the chirp generator, and to a control input on the controllable variable gain amplifier, said control unit adapted to output a first control signal to the chirp generator such that the chirp generator starts generating the chirp, output a second control signal to the controllable variable gain amplifier such that the controllable variable gain amplifier starts increasing an amplification in the controllable variable gain amplifier from a first amplification level, A 1, along a slope, to a second amplification level, A 2, during at least a portion of a time interval during which the chirp is generated, output a first control signal to the chirp generator such that the chirp generator starts generating the chirp, output a second control signal to the controllable variable gain amplifier such that the controllable variable gain amplifier starts increasing an amplification in the controllable variable gain amplifier from a first amplification level, A 1, along a slope, to a second amplification level, A 2, during at least a portion of a time interval during which the chirp is generated, wherein the control unit is adapted to output the first control signal and the second control signal such that the start of generating the chirp coincides with the start of the increase in amplification.
Selamectin for use in treating a sea lice parasitic infection or infestation on a fish, said treatment comprising orally administering to said fish a dose of 50 -150 μg/kg/day of selamectin.
A bio-pressure sensor system, comprising: a first sensor configured to provide a reference pressure measurement; a second sensor configured to measure a fluid pressure associated with a bodily fluid within a human body; wherein the first and second sensors (202, 205) are of substantially similar material properties and characteristics, a first reference element; and a second reference element in fluid communication with the first sensor and configured to provide a reference pressure, wherein the first and second sensors (202, 205) share the first reference element, and wherein the first and second sensors (202, 205) each comprise independent output signals (V 1, V 2), characterized by the second reference element comprising a reference fluid column, providing a known positional dependent reference pressure (P col (θ)). a first sensor configured to provide a reference pressure measurement; a second sensor configured to measure a fluid pressure associated with a bodily fluid within a human body; wherein the first and second sensors (202, 205) are of substantially similar material properties and characteristics, a first reference element; and a second reference element in fluid communication with the first sensor and configured to provide a reference pressure, wherein the first and second sensors (202, 205) share the first reference element, and wherein the first and second sensors (202, 205) each comprise independent output signals (V 1, V 2), characterized by the second reference element comprising a reference fluid column, providing a known positional dependent reference pressure (P col (θ)).
A bit holder for holding a bit for coupling the bit to a drive tool, the bit holder comprising: a receiving device which is designed to receive the bit; and a tool coupling, which is designed for coupling with the drive tool, characterized by a fixing sleeve for fixing the bit to the receiving device; the bit holder furthermore having an impact load protection device which is designed to protect the fixing sleeve from an impact load acting on the fixing sleeve when the bit holder abuts against an anchoring base, when a fastening element to be driven by means of the bit, the drive tool and the bit holder is introduced into the anchoring base, in particular is introduced in a rotating manner. a receiving device which is designed to receive the bit; and a tool coupling, which is designed for coupling with the drive tool, a fixing sleeve for fixing the bit to the receiving device; the bit holder furthermore having an impact load protection device which is designed to protect the fixing sleeve from an impact load acting on the fixing sleeve when the bit holder abuts against an anchoring base, when a fastening element to be driven by means of the bit, the drive tool and the bit holder is introduced into the anchoring base, in particular is introduced in a rotating manner.
A disposable absorbent insert for use with an outer cover adapted to be worn about a wearer's lower torso, the insert having a longitudinal length, an insert forward region with a forward end, an insert rearward region with a rearward end, and an insert lateral axis between the forward and rearward regions (54, 55) and equally dividing the longitudinal length, comprising a fastener component (56, 57) disposed at least one of the insert forward region and the insert rearward region, the insert characterized in that the forward end or the rearward end of the at least one of the insert forward region and the insert rearward region (54,55) bearing the fastener component (56, 57) has a Bending Stiffness of between about 50 N/m and 1,000 N/m, as measured according to the test method set out herein, wherein the insert further comprises a disposal aid disposed thereon.
An injection moulding unit for an injection moulding machine for processing plastics and other plasticisable substances, comprising - a carrier block with a receiving bore, - a replaceable plasticiser cylinder of a plasticiser unit, the plasticiser cylinder being removably receivable in the receiving bore, in which plasticiser cylinder there is arranged a feeding means which is movable along an injection axis (a-a), - a locking device for alternately locking the plasticiser unit on the carrier block and unlocking the plasticiser unit from the carrier block by relative movement of bevel surfaces running transversely to the injection axis (a-a) on operatively connected locking elements which are guided on bearing surfaces (10b, 20b) of the carrier block and/or plasticiser cylinder, characterised in that a bearing nut is provided on the outer surface of the plasticiser cylinder, the surface of said bearing nut oriented in the direction of the carrier block forms at least one of the bearing surfaces, and in that a plurality of locking elements are provided which either have bevel surfaces which are oriented toward each other, independently of the carrier block and plasticiser cylinder, and which slide on each other during a locking movement and during an unlocking movement, or have, on the side spaced from the bearing surface of the bearing nut, oppositely inclined bevel surfaces which slide synchronously on bevel surfaces of the carrier block during a locking movement and during an unlocking movement. - a carrier block with a receiving bore, - a replaceable plasticiser cylinder of a plasticiser unit, the plasticiser cylinder being removably receivable in the receiving bore, in which plasticiser cylinder there is arranged a feeding means which is movable along an injection axis (a-a), - a locking device for alternately locking the plasticiser unit on the carrier block and unlocking the plasticiser unit from the carrier block by relative movement of bevel surfaces running transversely to the injection axis (a-a) on operatively connected locking elements which are guided on bearing surfaces (10b, 20b) of the carrier block and/or plasticiser cylinder, characterised in that a bearing nut is provided on the outer surface of the plasticiser cylinder, the surface of said bearing nut oriented in the direction of the carrier block forms at least one of the bearing surfaces, and in that a plurality of locking elements are provided which either have bevel surfaces which are oriented toward each other, independently of the carrier block and plasticiser cylinder, and which slide on each other during a locking movement and during an unlocking movement, or have, on the side spaced from the bearing surface of the bearing nut, oppositely inclined bevel surfaces which slide synchronously on bevel surfaces of the carrier block during a locking movement and during an unlocking movement.
Process for separating an isocyanate prepared by reaction of a primary amine with an excess of phosgene in the gas phase from the gaseous crude product obtained in the reaction, wherein (i) the gaseous crude product, which comprises at least isocyanate, hydrogen chloride and unreacted phosgene, is converted by contacting with at least one quenching liquid into a liquid phase comprising at least quenching liquid and isocyanate and into a gas phase comprising at least hydrogen chloride and phosgene, (ii) the gas phase obtained in step (i) is partially condensed, (iii) the condensate obtained in step (ii) is used as the quenching liquid in step (i), (iv) the portions of the gas phase that were not condensed in step (ii) are at least partially liquefied to obtain a liquid phase, (v) the liquid phase obtained in step (iv) is likewise used as the quenching liquid in step (i), and (vi) the liquid phase obtained in step (i) is worked up to the pure isocyanate without previously being used as quenching liquid. (i) the gaseous crude product, which comprises at least isocyanate, hydrogen chloride and unreacted phosgene, is converted by contacting with at least one quenching liquid into a liquid phase comprising at least quenching liquid and isocyanate and into a gas phase comprising at least hydrogen chloride and phosgene, (ii) the gas phase obtained in step (i) is partially condensed, (iii) the condensate obtained in step (ii) is used as the quenching liquid in step (i), (iv) the portions of the gas phase that were not condensed in step (ii) are at least partially liquefied to obtain a liquid phase, (v) the liquid phase obtained in step (iv) is likewise used as the quenching liquid in step (i), and (vi) the liquid phase obtained in step (i) is worked up to the pure isocyanate without previously being used as quenching liquid.
Method of operating a gas turbine system in part load operation, characterized in that - with a given operating state of a flow medium flowing into a compressor of the gas turbine system, a compressor pre-guide blade adjustment for part load operation is initiated, - at least one temperature and/or humidity of the flow medium flowing in is determined in the operating state, - depending on the determined temperature and/or humidity of the flow medium flowing in, a compressor pre-guide blade adjustment limit value is determined in operation, - a value of the initiated compressor pre-guide blade adjustment is compared with the compressor pre-guide blade adjustment limit value which is determined in operation, and - if the value of the initiated compressor pre-guide blade adjustment fulfils a predefined condition with regard to the compressor pre-guide blade adjustment limit value which is determined in operation, - at least one measure is initiated for changing the state (96, 98, 102-106) of the flow medium flowing into the compressor of the gas turbine system in part load operation. - with a given operating state of a flow medium flowing into a compressor of the gas turbine system, a compressor pre-guide blade adjustment for part load operation is initiated, - at least one temperature and/or humidity of the flow medium flowing in is determined in the operating state, - depending on the determined temperature and/or humidity of the flow medium flowing in, a compressor pre-guide blade adjustment limit value is determined in operation, - a value of the initiated compressor pre-guide blade adjustment is compared with the compressor pre-guide blade adjustment limit value which is determined in operation, and - if the value of the initiated compressor pre-guide blade adjustment fulfils a predefined condition with regard to the compressor pre-guide blade adjustment limit value which is determined in operation, - at least one measure is initiated for changing the state (96, 98, 102-106) of the flow medium flowing into the compressor of the gas turbine system in part load operation.
A deployable reflector system, comprising: a support structure; a reflector surface connected to the support structure; the reflector surface comprised of a carbon nanotube, CNT, sheet which is highly reflective of electromagnetic waves; the support structure configured to transition from a compact stowed configuration to a larger deployed configuration; the CNT sheet intricately folded in accordance with a predetermined folding pattern to define a compact folded state when the support structure is in the stowed configuration; and the predetermined folding pattern configured to permit automatic extension of the CNT sheet from the compact folded state to a fully unfolded state when a tension force is applied to at least a portion of the CNT sheet by the support structure, wherein the reflector-system is characterized in that the CNT sheet is comprised of a plurality of separate pieces of CNT sheet which are bonded together in a predetermined piece pattern so as to form a concave or parabolic shape when the CNT sheet is in the fully unfolded state. a support structure; a reflector surface connected to the support structure; the reflector surface comprised of a carbon nanotube, CNT, sheet which is highly reflective of electromagnetic waves; the support structure configured to transition from a compact stowed configuration to a larger deployed configuration; the CNT sheet intricately folded in accordance with a predetermined folding pattern to define a compact folded state when the support structure is in the stowed configuration; and the predetermined folding pattern configured to permit automatic extension of the CNT sheet from the compact folded state to a fully unfolded state when a tension force is applied to at least a portion of the CNT sheet by the support structure, wherein the reflector-system is characterized in that the CNT sheet is comprised of a plurality of separate pieces of CNT sheet which are bonded together in a predetermined piece pattern so as to form a concave or parabolic shape when the CNT sheet is in the fully unfolded state.
A computer program for assisting a physician to perform reduction of complex fractures, the computer program comprising instructions which when executed on a processing unit of a device cause the device to execute the steps of: receiving a 2D x-ray image of a fractured bone having a plurality of bone fragments (10, 11, 12, 13), said 2D x-ray image being captured from a first direction, identifying, manually through input means or automatically, a structural aspect (21, 22) of at least one of the bone fragments in the first 2D x-ray image, identifying a reference body shown in the 2D x-ray image, wherein the reference body is formed by a plurality of radiopaque elements which are provided with a predetermined 3D position relative to each other such that the 3D orientation of the reference body is determined based on a single 2D projection image, and wherein the physician has the possibility to hold or move a bone fragment by means of the reference body, adapting, based on the identified structural aspect, a virtual bone model from a database to the imaged fracture bone, with the virtual bone model representing a real bone of the same kind without fractures, (S5,S6) generating and showing an overlay of the virtual bone model onto the 2D x-ray image, with the virtual bone model aligned to the identified structural aspect (21,22), and automatically indicating, in the shown image, directions and distances for manual repositioning of the respective bone fragments by means of said reference body such that they fit into the contour of the bone model, repeating the above steps (S1 to S6) from a further direction, or again from the first direction to control the results of the repositioning. receiving a 2D x-ray image of a fractured bone having a plurality of bone fragments (10, 11, 12, 13), said 2D x-ray image being captured from a first direction, identifying, manually through input means or automatically, a structural aspect (21, 22) of at least one of the bone fragments in the first 2D x-ray image, identifying a reference body shown in the 2D x-ray image, wherein the reference body is formed by a plurality of radiopaque elements which are provided with a predetermined 3D position relative to each other such that the 3D orientation of the reference body is determined based on a single 2D projection image, and wherein the physician has the possibility to hold or move a bone fragment by means of the reference body, adapting, based on the identified structural aspect, a virtual bone model from a database to the imaged fracture bone, with the virtual bone model representing a real bone of the same kind without fractures, (S5,S6) generating and showing an overlay of the virtual bone model onto the 2D x-ray image, with the virtual bone model aligned to the identified structural aspect (21,22), and automatically indicating, in the shown image, directions and distances for manual repositioning of the respective bone fragments by means of said reference body such that they fit into the contour of the bone model, repeating the above steps (S1 to S6) from a further direction, or again from the first direction to control the results of the repositioning.