A surgical access device, comprising: (a) a cannula having a proximal end, a distal end, and a cannula lumen (35, 124) extending therebetween; (b) a housing coupled to the proximal end of the cannula, wherein the housing defines a housing interior (27, 130) in communication with the cannula lumen (35, 124); (c) a working channel (38, 132, 286) extending between proximal and distal ends of the surgical access device along a central axis thereof, wherein the working channel is defined by the cannula lumen (35, 124) and the housing interior (27, 130), wherein the working channel is configured to receive a surgical instrument therethrough; (d) a needle entrance port (150, 320, 416) arranged on a side portion of the housing, wherein the needle entrance port opens to the working channel; and (e) a needle exit port (152, 320, 418) arranged distally of the needle entrance port on a side portion of the cannula, wherein the needle exit port communicates with the needle entrance port to define a suture path extending through the surgical access device at an oblique angle relative to the central axis, characterised in that the surgical access device further comprises (f) a suture passer guide tube extending through the needle entrance and exit ports, wherein the suture passer guide tube includes a distal tube end positioned outwardly of the cannula at a predetermined radial distance from the central axis; wherein when the cannula is positioned within a first tissue of a first thickness, the needle entrance and exit ports are configured to guide a suture passer device through the surgical access device and the first tissue to define a tissue bite distance in the first tissue, wherein when the cannula is positioned within a second tissue of a second thickness different than the first thickness, the needle entrance and exit ports are configured to guide the suture passer device through the surgical access device and the second tissue to define the same tissue bite distance in the second tissue; wherein the suture passer guide tube is configured to guide a suture passer device distally through the surgical access device and the first and second tissues; and wherein the suture passer guide tube comprises a proximal tube portion defining a proximal tube end, and a distal tube portion defining the distal tube end, wherein the distal tube portion is angled relative to the proximal tube portion; wherein the distal tube portion extends along an axis parallel to the central axis. (a) a cannula having a proximal end, a distal end, and a cannula lumen (35, 124) extending therebetween; (b) a housing coupled to the proximal end of the cannula, wherein the housing defines a housing interior (27, 130) in communication with the cannula lumen (35, 124); (c) a working channel (38, 132, 286) extending between proximal and distal ends of the surgical access device along a central axis thereof, wherein the working channel is defined by the cannula lumen (35, 124) and the housing interior (27, 130), wherein the working channel is configured to receive a surgical instrument therethrough; (d) a needle entrance port (150, 320, 416) arranged on a side portion of the housing, wherein the needle entrance port opens to the working channel; and (e) a needle exit port (152, 320, 418) arranged distally of the needle entrance port on a side portion of the cannula, wherein the needle exit port communicates with the needle entrance port to define a suture path extending through the surgical access device at an oblique angle relative to the central axis, characterised in that the surgical access device further comprises (f) a suture passer guide tube extending through the needle entrance and exit ports, wherein the suture passer guide tube includes a distal tube end positioned outwardly of the cannula at a predetermined radial distance from the central axis; wherein when the cannula is positioned within a first tissue of a first thickness, the needle entrance and exit ports are configured to guide a suture passer device through the surgical access device and the first tissue to define a tissue bite distance in the first tissue,