mhurhangee/ep-ind-claims huggingface dataset:
A method for at least partially reversing deterioration of an apatite-based chromatography resin resulting from purification of a target molecule with said resin, said method comprising equilibrating the apatite-based chromatography resin, loading the target molecule onto the apatite-based chromatography resin, eluting the target molecule from the apatite-based chromatography resin, and then post-elution: (a) passing a solution of calcium ion through said resin; (b) passing a solution of phosphate ion having a pH of at least about 6.5 through said resin; and (c) passing a solution of hydroxide ion through said resin; steps (a), (b), and (c) being performed separately from any passage of equilibration, sample loading, and elution buffers through said resin and at concentrations of said ions and at volumes of said solutions that are effective to at least partially reverse deterioration of said resin caused by said elution buffer, and - wherein step (a) is performed before step (b), and step (b) is performed before step (c); - said solution of calcium ion has a calcium ion concentration of from 10 ppm to 2000 ppm, and is passed through said resin in an amount of from 1.0 resin volume to 10.0 resin volumes; - said solution of phosphate ion has a pH of from 6.5 to 9.0, has a phosphate ion concentration of from 50 mM to 1 M, and is passed through said resin in an amount of from 1.0 resin volume to 20.0 resin volumes; and - said solution of hydroxide ion has a hydroxide ion concentration of from 0.1 M to 5.0 M, and is passed through said resin in an amount of from 1.0 resin volume to 20.0 resin volumes, and wherein said deterioration of said apatite-based chromatography resin comprises a loss of resin mass and/or resin particle strength of said apatite-based chromatography resin. (a) passing a solution of calcium ion through said resin; (b) passing a solution of phosphate ion having a pH of at least about 6.5 through said resin; and (c) passing a solution of hydroxide ion through said resin; - wherein step (a) is performed before step (b), and step (b) is performed before step (c); - said solution of calcium ion has a calcium ion concentration of from 10 ppm to 2000 ppm, and is passed through said resin in an amount of from 1.0 resin volume to 10.0 resin volumes; - said solution of phosphate ion has a pH of from 6.5 to 9.0, has a phosphate ion concentration of from 50 mM to 1 M, and is passed through said resin in an amount of from 1.0 resin volume to 20.0 resin volumes; and - said solution of hydroxide ion has a hydroxide ion concentration of from 0.1 M to 5.0 M, and is passed through said resin in an amount of from 1.0 resin volume to 20.0 resin volumes, and
A variant, recombinant human β-glucocerebrosidase protein having a mutation selected from: F316A and L317F; H145L; H145F; H145L, F316A and L317F; K321A; and K321V; relative to the amino acid sequence of SEQ ID NO: 1. F316A and L317F; H145L; H145F; H145L, F316A and L317F; K321A; and K321V;
Shoe upper (100; 400; 500), comprising: a. an area (110; 410; 510) comprising a contiguous piece of natural and / or synthetic leather, b. wherein the area (110; 410; 510) comprises a first sub-area (120; 420; 520) and a second sub-area (130; 131; 430; 530), each sub-area (120; 130; 131; 420; 430; 520; 530) having a size of more than 3 cm 2, in particular more than 4 cm 2, c. wherein the leather has a reduced thickness in the second sub-area (130; 131; 430; 530) compared to the first sub-area (120; 420; 520), and d. wherein the reduced thickness is obtained by milling off a first surface layer of the leather in the entire second sub-area (130; 131; 430; 530). a. an area (110; 410; 510) comprising a contiguous piece of natural and / or synthetic leather, b. wherein the area (110; 410; 510) comprises a first sub-area (120; 420; 520) and a second sub-area (130; 131; 430; 530), each sub-area (120; 130; 131; 420; 430; 520; 530) having a size of more than 3 cm 2, in particular more than 4 cm 2, c. wherein the leather has a reduced thickness in the second sub-area (130; 131; 430; 530) compared to the first sub-area (120; 420; 520), and d. wherein the reduced thickness is obtained by milling off a first surface layer of the leather in the entire second sub-area (130; 131; 430; 530).
Double packaging for an object preferably intended to remain sterile until use, comprising: - a hollow external container extending generally along a longitudinal axis and comprising a first closed end, a second open end, and walls connecting the first and the second end, the second end being intended to be sealed by a closure system, - an internal container, placed inside the external container, comprising a hollow body and a stopper, the object being intended to be received in said body, the double packaging being characterized in that: - to close its first end, the external container includes a membrane capable of deforming when pressure is applied to it, - the membrane has an outer face and an inner face and is configured so that a pressure applied to its outer face, along the longitudinal axis, pushes its inner face against the internal container and causes the latter to exit at the second end of the external container, in the absence of the closure system. - a hollow external container extending generally along a longitudinal axis and comprising a first closed end, a second open end, and walls connecting the first and the second end, the second end being intended to be sealed by a closure system, - an internal container, placed inside the external container, comprising a hollow body and a stopper, the object being intended to be received in said body, - to close its first end, the external container includes a membrane capable of deforming when pressure is applied to it, - the membrane has an outer face and an inner face and is configured so that a pressure applied to its outer face, along the longitudinal axis, pushes its inner face against the internal container and causes the latter to exit at the second end of the external container, in the absence of the closure system.
A barrel element for a barrel extruder comprising: a body having an interior opening extending through a width of the body, wherein the body comprises: at least one injection port extending from a first external side of the body to the interior opening; a temperature sensor well extending from the first external side of the body towards the interior opening; a cooling inlet channel extending from a second external side of the body in a first direction; a cooling outlet channel extending from a third external side of the body in the first direction; and a plurality of connecting cooling channels (19, 20)extending in a second direction, wherein the cooling inlet channel and the cooling outlet channel are fluidly connected by the plurality of connecting cooling channels (19, 20). at least one injection port extending from a first external side of the body to the interior opening; a temperature sensor well extending from the first external side of the body towards the interior opening; a cooling inlet channel extending from a second external side of the body in a first direction; a cooling outlet channel extending from a third external side of the body in the first direction; and a plurality of connecting cooling channels (19, 20)extending in a second direction, wherein the cooling inlet channel and the cooling outlet channel are fluidly connected by the plurality of connecting cooling channels (19, 20).
Use of a chemical mechanical polishing composition for chemical mechanical polishing of a substrate comprising (i) cobalt and/or (ii) a cobalt alloy, wherein the CMP composition comprises Inorganic particles; an anionic surfactant of the general formula R-S wherein R is C 5 -C 20 -alkyl, C 5 -C 20 -alkenyl, C 5 -C 20 -alkylacyl or C 5 -C 20 -alkenylacy and S is a sulfonic acid derivative, an amino acid derivative or a phosphoric acid derivative or salts or mixtures thereof; at least one amino acid selected from the group consisting of glycine, alanine, leucine, valine, cysteine, serine and proline or a salt thereof; at least one oxidizer; an aqueous medium; and wherein the CMP composition has a pH of from 7 to 10; and wherein benzotriazole is not present in the CMP composition. Inorganic particles; an anionic surfactant of the general formula R-S wherein R is C 5 -C 20 -alkyl, C 5 -C 20 -alkenyl, C 5 -C 20 -alkylacyl or C 5 -C 20 -alkenylacy and S is a sulfonic acid derivative, an amino acid derivative or a phosphoric acid derivative or salts or mixtures thereof; at least one amino acid selected from the group consisting of glycine, alanine, leucine, valine, cysteine, serine and proline or a salt thereof; at least one oxidizer; an aqueous medium; and
Rail vehicle for transporting vehicles, in particular motor vehicles, wherein the rail vehicle is of least double-storey design and has a lower storey and an upper storey, and wherein each storey has a loading plane (14, 15) for parking vehicles, wherein the loading plane of the lower storey is formed from a plurality of elements (19, 20, 21, 22) which are designed to be at least partially adjustable for loading or unloading the vehicles on the one hand and for transporting the vehicles on the other hand, characterized in that the elements (19..22) are designed to be adjustable independent of one another, wherein one or more elements of the loading plane of the lower storey are designed to be only height-adjustable in the vertical direction and not pivotable between axles of the rail vehicle, and wherein one or more elements of the loading plane of the lower storey are designed to be height-adjustable in the vertical direction and pivotable between the axles and a head section of the rail vehicle.
A machine arrangement which operates on a plurality of articles comprising: a plurality of machines arranged to cooperate with each other in a manner to form the machine arrangement, the plurality of machines including at least one upstream machine and at least one downstream machine in the machine arrangement, at least one of the plurality of machines comprising an apparatus configured to modify the articles in at least one modifying operation as the articles pass from an article infeed to an article discharge of the machine arrangement; and a recirculation mechanism configured to move the articles from the at least one downstream machine after a first pass through the machine arrangement and recirculate the articles back to the at least one upstream machine in a recirculation pass so that the articles which are recirculated through the recirculation pass are subjected to a different modifying operation in a machine that the articles have previously passed through in the first pass, and wherein the recirculation mechanism comprises an article guide track which transfers the articles from the at least one downstream machine to the at least one upstream machine, characterised in that the article guide track comprises a belt and a track width adjusting arrangement (160, 170) that adjusts the track width of the article guide track to accommodate varying article sizes in a direction generally perpendicular to the surface of the belt, the belt including openings having a vacuum applied therethrough, the vacuum being configured to hold the articles onto the belt. a plurality of machines arranged to cooperate with each other in a manner to form the machine arrangement, the plurality of machines including at least one upstream machine and at least one downstream machine in the machine arrangement, at least one of the plurality of machines comprising an apparatus configured to modify the articles in at least one modifying operation as the articles pass from an article infeed to an article discharge of the machine arrangement; and a recirculation mechanism configured to move the articles from the at least one downstream machine after a first pass through the machine arrangement and recirculate the articles back to the at least one upstream machine in a recirculation pass so that the articles which are recirculated through the recirculation pass are subjected to a different modifying operation in a machine that the articles have previously passed through in the first pass, and wherein the recirculation mechanism comprises an article guide track which transfers the articles from the at least one downstream machine to the at least one upstream machine, characterised in that the article guide track comprises a belt and a track width adjusting arrangement (160, 170) that adjusts the track width of the article guide track to accommodate varying article sizes in a direction generally perpendicular to the surface of the belt, the belt including openings having a vacuum applied therethrough, the vacuum being configured to hold the articles onto the belt.
A method comprising: receiving (1101, 1102), from an image capture device coupled to a computing device, a first image of a face of a user, and a second image of the face of the user; detecting, by the computing device, a liveness gesture based on at least one of a yaw angle of the second image relative to the first image and a pitch angle of the second image relative to the first image, wherein the yaw angle corresponds to a transition of a head of the user centered around a vertical axis, and wherein the pitch angle corresponds to a transition of the head of the user centered around a horizontal axis, wherein detecting the liveness gesture is based at least in part on at least one facial landmark represented in one or both of the first image and the second image, wherein the yaw angle is obtained at least partly based on a detected presence of the at least one facial landmark in one of the first image and the second image and a detected absence of the at least one facial landmark in the respective other one of the first image and the second image; generating, by the computing device, a liveness score based on a yaw angle magnitude associated with the yaw angle; comparing, by the computing device, the liveness score to a threshold value; and determining (1110, 1114, 1116), by the computing device, based at least in part on the comparison, whether to deny authentication to the user with respect to accessing one or more functionalities controlled by the computing device. receiving (1101, 1102), from an image capture device coupled to a computing device, a first image of a face of a user, and a second image of the face of the user; detecting, by the computing device, a liveness gesture based on at least one of a yaw angle of the second image relative to the first image and a pitch angle of the second image relative to the first image, wherein the yaw angle corresponds to a transition of a head of the user centered around a vertical axis, and wherein the pitch angle corresponds to a transition of the head of the user centered around a horizontal axis, wherein detecting the liveness gesture is based at least in part on at least one facial landmark represented in one or both of the first image and the second image, wherein the yaw angle is obtained at least partly based on a detected presence of the at least one facial landmark in one of the first image and the second image and a detected absence of the at least one facial landmark in the respective other one of the first image and the second image; generating, by the computing device, a liveness score based on a yaw angle magnitude associated with the yaw angle; comparing, by the computing device, the liveness score to a threshold value; and determining (1110, 1114, 1116), by the computing device, based at least in part on the comparison, whether to deny authentication to the user with respect to accessing one or more functionalities controlled by the computing device.
Arrangement of a magnet-based rotational angle measuring system on a drive motor housing part, comprising a drive motor housing part, a drive shaft having a free end extending out of the drive motor housing part, an exciter unit non-rotatably connected to the drive shaft at the free end, a static sensor unit which functionally interacts with the exciter unit in order to detect a rotary movement of the drive shaft, and a shielding body arranged axially between the sensor unit and the drive motor housing part, characterized in that means for direct alignment of the sensor unit with respect to the drive motor housing part are provided, the means extending from the drive motor housing part to the sensor unit, wherein the shielding body comprises at least one recess through which the means extend in an axial direction.
A resin structure (1, 30) comprising: a resin molded body; and a plurality of electronic components embedded in the resin molded body, the resin molded body having a plurality of exposed surfaces (11, 13) on which electrodes of the plurality of electronic components are exposed, the resin molded body having a recess provided therein, the recess having a bottom surface which is at least one of the plurality of exposed surfaces, the resin structure (1, 30) further comprising a wiring provided on each of the plurality of exposed surfaces (11, 13), the wiring connecting between the electrodes exposed on the plurality of exposed surfaces (11, 13), characterized in that at least one of the electrodes is a electrode (3a-2, 3c-2, 3d-1, 3f-2) with multiple exposed faces which is exposed on at least two exposed surfaces (11, 13) that are different from each other; and the wiring is provided on each of the at least two exposed surfaces (11, 13), and includes a wiring being connected with the electrode with multiple exposed faces (3a-2, 3c-2, 3d-1, 3f-1). a resin molded body; and a plurality of electronic components embedded in the resin molded body, the resin molded body having a plurality of exposed surfaces (11, 13) on which electrodes of the plurality of electronic components are exposed, the resin molded body having a recess provided therein, the recess having a bottom surface which is at least one of the plurality of exposed surfaces, the resin structure (1, 30) further comprising a wiring provided on each of the plurality of exposed surfaces (11, 13), the wiring connecting between the electrodes exposed on the plurality of exposed surfaces (11, 13), characterized in that at least one of the electrodes is a electrode (3a-2, 3c-2, 3d-1, 3f-2) with multiple exposed faces which is exposed on at least two exposed surfaces (11, 13) that are different from each other; and the wiring is provided on each of the at least two exposed surfaces (11, 13), and includes a wiring being connected with the electrode with multiple exposed faces (3a-2, 3c-2, 3d-1, 3f-1).
A computer-implemented method comprising: receiving, for each of multiple utterances of a hotword, a first data set including at least (i) a speaker verification confidence score associated with the utterance, and (ii) environmental context data associated with the utterance; selecting from among a plurality of data set clusters, a data set cluster that is associated with a particular environmental context; selecting a second data set from among the selected data set cluster based on one or more selection criteria; selecting, as a speaker verification threshold for the particular environmental context, the speaker verification confidence score included in the second data set; and providing the speaker verification threshold for use in performing speaker verification of utterances that are associated with the particular environmental context. receiving, for each of multiple utterances of a hotword, a first data set including at least (i) a speaker verification confidence score associated with the utterance, and (ii) environmental context data associated with the utterance; selecting from among a plurality of data set clusters, a data set cluster that is associated with a particular environmental context; selecting a second data set from among the selected data set cluster based on one or more selection criteria; selecting, as a speaker verification threshold for the particular environmental context, the speaker verification confidence score included in the second data set; and providing the speaker verification threshold for use in performing speaker verification of utterances that are associated with the particular environmental context.
A liquid ejecting head comprising: a piezoelectric element that includes a first drive electrode, a second drive electrode, and a piezoelectric body, the piezoelectric body being provided between the first drive electrode and the second drive electrode in a lamination direction in which the first drive electrode, the second drive electrode, and the piezoelectric body are laminated; a vibration plate that is provided on one side of the lamination direction with respect to the piezoelectric element and is deformed by driving of the piezoelectric element; and a pressure chamber substrate that is provided on the one side of the lamination direction with respect to the vibration plate and is provided with a plurality of pressure chambers, characterized by further comprising an interlayer that is laminated on at least one of the piezoelectric body, the vibration plate, or the pressure chamber substrate and of which capacitance changes according to humidity; a first detection electrode that is in contact with the interlayer; and a second detection electrode that is in contact with the interlayer and is disposed to be separated from the first detection electrode. a piezoelectric element that includes a first drive electrode, a second drive electrode, and a piezoelectric body, the piezoelectric body being provided between the first drive electrode and the second drive electrode in a lamination direction in which the first drive electrode, the second drive electrode, and the piezoelectric body are laminated; a vibration plate that is provided on one side of the lamination direction with respect to the piezoelectric element and is deformed by driving of the piezoelectric element; and a pressure chamber substrate that is provided on the one side of the lamination direction with respect to the vibration plate and is provided with a plurality of pressure chambers, characterized by further comprising an interlayer that is laminated on at least one of the piezoelectric body, the vibration plate, or the pressure chamber substrate and of which capacitance changes according to humidity; a first detection electrode that is in contact with the interlayer; and a second detection electrode that is in contact with the interlayer and is disposed to be separated from the first detection electrode.