mhurhangee/ep-ind-claims huggingface dataset:
A monoclonal antibody, or an antigen-binding portion thereof, that specifically binds to a filovirus, wherein the antibody or antigen-binding portion comprises: (a) an immunoglobulin light chain variable region comprising LCDR1, LCDR2, and LCDR3, and an immunoglobulin heavy chain variable region comprising HCDR1, HCDR2, and HCDR3, wherein the LCDR1, LCDR2 and LCDR3 comprise the amino acid sequences set forth in SEQ ID NOs: 78, 79 and 80, respectively, and the HCDR1, HCDR2, and HCDR3 comprise the amino acid sequences set forth in SEQ ID NOs: 90, 91 and 92, respectively; or (b) an immunoglobulin light chain variable region comprising the amino acid sequence set forth in SEQ ID NO:2 and an immunoglobulin heavy chain variable region comprising the amino acid sequence set forth in SEQ ID NO:14; or (c) an immunoglobulin light chain variable region comprising the amino acid sequence set forth in SEQ ID NO:26 and an immunoglobulin heavy chain variable region comprising the amino acid sequence set forth in SEQ ID NO:38. (a) an immunoglobulin light chain variable region comprising LCDR1, LCDR2, and LCDR3, and an immunoglobulin heavy chain variable region comprising HCDR1, HCDR2, and HCDR3, wherein the LCDR1, LCDR2 and LCDR3 comprise the amino acid sequences set forth in SEQ ID NOs: 78, 79 and 80, respectively, and the HCDR1, HCDR2, and HCDR3 comprise the amino acid sequences set forth in SEQ ID NOs: 90, 91 and 92, respectively; or (b) an immunoglobulin light chain variable region comprising the amino acid sequence set forth in SEQ ID NO:2 and an immunoglobulin heavy chain variable region comprising the amino acid sequence set forth in SEQ ID NO:14; or (c) an immunoglobulin light chain variable region comprising the amino acid sequence set forth in SEQ ID NO:26 and an immunoglobulin heavy chain variable region comprising the amino acid sequence set forth in SEQ ID NO:38.
A pharmaceutical composition in the form of a capsule which achieves an in vitro initial rise in pH within about 4 minutes comprising: (a) 10 mg to 100 mg of at least one acid labile bicyclic-aryl-imidazole proton pump inhibiting agent; (b) at least one anatacid in an amount sufficient to increase gastric fluid pH to a pH that prevents acid degradation of at least some of the proton pump inhibitor in the gastric fluid; wherein the antacid comprises at least 400 mg of NaHCO 3; and (c) 0.5 wt-% to 3 wt-% of the hydrophilic lubricant sodium stearyl fumarate (a) 10 mg to 100 mg of at least one acid labile bicyclic-aryl-imidazole proton pump inhibiting agent; (b) at least one anatacid in an amount sufficient to increase gastric fluid pH to a pH that prevents acid degradation of at least some of the proton pump inhibitor in the gastric fluid; wherein the antacid comprises at least 400 mg of NaHCO 3; and (c) 0.5 wt-% to 3 wt-% of the hydrophilic lubricant sodium stearyl fumarate
A smoking article component including a curved sheet wrapper that includes a plurality of lines of strength discontinuity whereat the wrapper presents a visually discernable non-uniformity in its curvature, and includes lap seams along opposite side edges (9a, 9b, 66, 67) that include lines of weakness (15a, 15b) that permit intimate overlying abutment of side edges (9a, 9b, 66, 67) of the wrapper.
A method of preserving privacy for usage of a lightweight blockchain client in a blockchain network, the method comprising: using, in a full blockchain node of the blockchain network, a trusted execution environment, TEE; establishing a secure communication between the lightweight blockchain client and the TEE; receiving, by the TEE, a request from the lightweight blockchain client for at least one transaction or address of the lightweight blockchain client; and obtaining, by the TEE, unspent transaction output, UTXO, information in respect to the lightweight blockchain client's request from a UTXO database by means of oblivious database access using an oblivious RAM, ORAM, protocol, and removing, by the TEE in order to protect against internal leakage, all branching in the code that accesses the ORAM data structures and replacing the branching with cmov assembly instructions. using, in a full blockchain node of the blockchain network, a trusted execution environment, TEE; establishing a secure communication between the lightweight blockchain client and the TEE; receiving, by the TEE, a request from the lightweight blockchain client for at least one transaction or address of the lightweight blockchain client; and obtaining, by the TEE, unspent transaction output, UTXO, information in respect to the lightweight blockchain client's request from a UTXO database by means of oblivious database access using an oblivious RAM, ORAM, protocol, and removing, by the TEE in order to protect against internal leakage, all branching in the code that accesses the ORAM data structures and replacing the branching with cmov assembly instructions.
A topical composition comprising an active agent comprising a peptide having an amino acid sequence comprising or consisting of M 2 VV or M VV, wherein the methionine amino acid residue of said sequence is oxidized.
A travel region specifying device comprising: a positional information acquirer configured to acquire positional information of a body part of a work vehicle; a travel trajectory region specifier configured to specify a travel trajectory region of the body part based on a travel trajectory of the body part specified using the positional information, said travel trajectory region being a closed region surrounded by the travel trajectory; and a travel region specifier configured to specify a field shape as a travel region where the body part travels based on a plurality of selection points selected from the travel trajectory by an operator; characterized by comprising: a notifier configured to issue a predetermined notification, wherein the predetermined notification is a notification suggesting that the travel region includes a region outside the travel trajectory region. a positional information acquirer configured to acquire positional information of a body part of a work vehicle; a travel trajectory region specifier configured to specify a travel trajectory region of the body part based on a travel trajectory of the body part specified using the positional information, said travel trajectory region being a closed region surrounded by the travel trajectory; and a travel region specifier configured to specify a field shape as a travel region where the body part travels based on a plurality of selection points selected from the travel trajectory by an operator; characterized by comprising: a notifier configured to issue a predetermined notification, wherein the predetermined notification is a notification suggesting that the travel region includes a region outside the travel trajectory region. a notifier configured to issue a predetermined notification, wherein the predetermined notification is a notification suggesting that the travel region includes a region outside the travel trajectory region.
A photovoltaic module comprising a plurality of thin film photovoltaic cells positioned on a transparent substrate, each thin film photovoltaic cell comprising a transparent electrode provided on the transparent substrate, a solar cell stack positioned on the transparent electrode, and a top electrode positioned on the solar cell stack, wherein a plurality of parallel connected photovoltaic cell units are provided, each comprising a string of series connected photovoltaic cells, the photovoltaic module further comprising a positive connection part (6, 20a) and a negative connection part (5, 20b) in a single top interconnection layer, providing the parallel connection circuit of the parallel connected photovoltaic cell units, characterised in that at least one cross over connection member (9a, 9b) is present in a layer different from the single top interconnection layer, the at least one cross over connection member (9a, 9b) providing an electrical connection in the negative connection part (5, 20b) and/or in the positive connection part (6, 20a).
Microwave cooking appliance, including: an interior chamber including a cooking space; an apparatus (38,39) for providing microwaves of at least one wavelength λ to the interior chamber; and a rotatable device (47,48) for homogenising an energy distribution in the cooking space, the device (47,48) being driven by fluid flow past at least one first fan blade (49a-h,52a-d,53a-d) and provided with at least one of reflective and resonant structures arranged in the interior chamber, characterised in that the rotatable device (47,48) further includes at least one device for adjusting at least one of the first fan blades (49a-h,52a-d,53a-d) in dependence on at least one of a speed of rotation, centrifugal forces and forces exerted by the fluid flow on the first blade (49ah,52a-d,53a-d). an interior chamber including a cooking space; an apparatus (38,39) for providing microwaves of at least one wavelength λ to the interior chamber; and a rotatable device (47,48) for homogenising an energy distribution in the cooking space, the device (47,48) being driven by fluid flow past at least one first fan blade (49a-h,52a-d,53a-d) and provided with at least one of reflective and resonant structures arranged in the interior chamber, characterised in that the rotatable device (47,48) further includes at least one device for adjusting at least one of the first fan blades (49a-h,52a-d,53a-d) in dependence on at least one of a speed of rotation, centrifugal forces and forces exerted by the fluid flow on the first blade (49ah,52a-d,53a-d).
A solenoid comprising: a magnetic frame; a pick up coil having a pick up coil length wound around a portion of a bobbin in a radial level; the bobbin having a length that equals the sum of the pick up coil length and the remaining bobbin portion; a hold coil; a fixed pole; a movable armature having a length; and a return spring biasing the armature away from the pole; wherein said solenoid includes a pick up state when the armature and the pole are separated by a magnetic gap, and a holding state when the armature and the pole are proximate each other; wherein the pick up coil is wound around the bobbin for a portion of the length of the bobbin and the hold coil is wound around the bobbin for the remaining portion of the length of the bobbin; and wherein the length of the pick up coil is about the same as the length of the armature and is less than the length of the bobbin; wherein the pick up coil is first wound around said portion of the bobbin for a portion of the length of the bobbin but not all of the length of the bobbin; wherein the hold coil is placed at an end of the pick up coil in the remaining portion of the length of the bobbin; and wherein of the remaining turns of the hold coil are wound across the complete length of the bobbin to a further radial level that is greater than said radial level after the hold coil and the pick up coil are both wound to said radial level on the bobbin. a magnetic frame; a pick up coil having a pick up coil length wound around a portion of a bobbin in a radial level; the bobbin having a length that equals the sum of the pick up coil length and the remaining bobbin portion; a hold coil; a fixed pole; a movable armature having a length; and a return spring biasing the armature away from the pole; wherein said solenoid includes a pick up state when the armature and the pole are separated by a magnetic gap, and a holding state when the armature and the pole are proximate each other; wherein the pick up coil is wound around the bobbin for a portion of the length of the bobbin and the hold coil is wound around the bobbin for the remaining portion of the length of the bobbin; and wherein the length of the pick up coil is about the same as the length of the armature and is less than the length of the bobbin; wherein the pick up coil is first wound around said portion of the bobbin for a portion of the length of the bobbin but not all of the length of the bobbin; wherein the hold coil is placed at an end of the pick up coil in the remaining portion of the length of the bobbin; and wherein of the remaining turns of the hold coil are wound across the complete length of the bobbin to a further radial level that is greater than said radial level after the hold coil and the pick up coil are both wound to said radial level on the bobbin.
A flexible matrix for supporting repair of biological tissues comprising a high molecular weight caprolactone polymer entangled with hyaluronic acid polymers by a process of dual solvent emulsion, optionally further comprising at least one flexibility agent entangled with the hyaluronic acid polymers, wherein the matrix is characterized by (i) retention of flexibility, compressive resistance and conformability when manipulated during a surgery, and (ii) the ability to support the growth of cells in vivo or ex vivo, and wherein said dual solvent emulsion is formed by the steps of: (i) dissolving the caprolactone polymer in an organic solvent; (ii) dissolving the hyaluronic acid polymers in an aqueous solvent; and (iii) blending the caprolactone polymer in the organic solvent with the hyaluronic acid polymers in an aqueous solvent to form the dual solvent emulsion. (i) dissolving the caprolactone polymer in an organic solvent; (ii) dissolving the hyaluronic acid polymers in an aqueous solvent; and (iii) blending the caprolactone polymer in the organic solvent with the hyaluronic acid polymers in an aqueous solvent to form the dual solvent emulsion.
A torque sensor unit comprising: - a ring magnet which can be connected to a first partial shaft for conjoint rotation and a magnetic flux conductor which can be connected to a second partial shaft, - a sensor unit having a first housing, wherein the sensor unit detects a change in rotational angle between the partial shafts (30, 31), - a second housing, which surrounds the ring magnet and the magnetic flux conductor and is fixedly connected to the first housing of the sensor unit, characterized in that the second housing of the torque sensor unit has a housing opening into which the first housing of the sensor unit is pressed to form a frictional connection, wherein the housing opening has a first profile on at least two side faces. - a ring magnet which can be connected to a first partial shaft for conjoint rotation and a magnetic flux conductor which can be connected to a second partial shaft, - a sensor unit having a first housing, wherein the sensor unit detects a change in rotational angle between the partial shafts (30, 31), - a second housing, which surrounds the ring magnet and the magnetic flux conductor and is fixedly connected to the first housing of the sensor unit, characterized in that the second housing of the torque sensor unit has a housing opening into which the first housing of the sensor unit is pressed to form a frictional connection, wherein the housing opening has a first profile on at least two side faces.
An electrical network, comprising: parallel operated units (2; 2.1 - 2.N) which are droop controlled for active and reactive power sharing and connected to each other via impedances and protection switches (14, 15) for detecting a short circuit on the electrical network and for disconnecting the faulty part of the electrical network, said units (2; 2.1 - 2.N) including a direct current source (10.1 - 10.N) and a grid forming voltage source inverter (3; 3.1 - 3.N) which is controlled by a cascaded control structure comprising a voltage controller and a short circuit controller for limiting an output current (I 1 or I 2) and an output voltage ( V 2) at the output terminals of the inverter (3; 3.1 - 3.N), characterized in that said voltage controller and said short circuit controller are configured to limit the output current (I 1 or I 2) and the output voltage ( V 2) at the output terminals of the inverter (3; 3.1 - 3.N) as a function of a measured output current (I 1, I 2) and a desired droop voltage ( V ̃ 2 d) provided by a droop control for voltage and frequency power sharing. parallel operated units (2; 2.1 - 2.N) which are droop controlled for active and reactive power sharing and connected to each other via impedances and protection switches (14, 15) for detecting a short circuit on the electrical network and for disconnecting the faulty part of the electrical network, said units (2; 2.1 - 2.N) including a direct current source (10.1 - 10.N) and a grid forming voltage source inverter (3; 3.1 - 3.N) which is controlled by a cascaded control structure comprising a voltage controller and a short circuit controller for limiting an output current (I 1 or I 2) and an output voltage ( V 2) at the output terminals of the inverter (3; 3.1 - 3.N), characterized in that said voltage controller and said short circuit controller are configured to limit the output current (I 1 or I 2) and the output voltage ( V 2) at the output terminals of the inverter (3; 3.1 - 3.N) as a function of a measured output current (I 1, I 2) and a desired droop voltage ( V ̃ 2 d) provided by a droop control for voltage and frequency power sharing.
Use of sensor read out system with at least one fiber optical sensor, which is connected via at least one signal line to a processing unit as part of an additive manufacturing setup, for in situ and real time quality control of a running ion and electron beams, microwave or laser additive manufacturing process, wherein acoustic emission is measured via the at least one fiber optical sensor in form of fibers with Bragg grating, fibre interferometer or Fabry-Perot structure, followed by a signal transfer and an analysis of the measured signals in the processing unit, estimation of the additive manufacturing process quality due to correlation between sintering or melting quality and measured acoustic emission signals and subsequent adaption of additive manufacturing parameters of an ion and electron beams, microwave or laser electronics of the additive manufacturing setup in real times via a feedback loop as a result of the measured acoustic emission signals after interpretation with an algorithmic framework in the processing unit, wherein the at least one optical fiber sensor is arranged separated from the sample and source alongside a process axis between the ion and electron beams, microwave or laser source and the ion and electron beams, microwave or laser irradiation focused spot, and the at least one optical fiber sensor respectively its fiber axis (f) is tilted in an angle (Θ) of range 0° to 90° relative to the process axis.
Microorganism strain for the production of low-molecular-weight substances or proteins, containing in its genome a mutation in a gene, which mutation brings about an auxotrophy in the strain, and also a production plasmid encoding at least one enzyme for the production of a low-molecular-weight substance or at least one recombinant protein and also a functional copy of the gene, the chromosomal inactivation of which brings about the auxotrophy, characterized in that the auxotrophy is a nonfeedable auxotrophy and the gene is the pyrH gene having SEQ ID No.1 or a pyrH -homologous gene, wherein a nonfeedable auxotrophy is to be understood to mean that the auxotrophy reduces the growth of the microorganism cell or brings about the death of the microorganism cell and is not supplementable by addition of metabolism-specific precursors, intermediates and/or end products to the growth medium and wherein the pyrH-homologous genes are genes which code for a protein having pyrH activity and which have a sequence identity greater than 30% in relation to SEQ ID No.1.
An optical device (100, 200), comprising: a free space optical region (120, 220); one or more input optical waveguides (110, 210) end connected to the free space optical region (120, 220) along a first surface thereof; and one or more output optical waveguides (130, 230) end connected to the free space optical region (120, 220) along a second surface thereof, the second surface facing the first surface; wherein the set of input and output optical waveguides (110, 210, 130, 230) includes at least three optical waveguides, wherein at least one of the one or more input optical waveguides supports multi-mode propagation and includes an offset at joined ends of an input portion and an output portion thereof, the output portion end connecting to the first surface; and wherein the offset is adapted to cause an oscillating mode in the at least one of the one or more input optical waveguides such that the oscillating mode moves transversely in a zig-zag pattern along a length of the one of the one or more input optical waveguides. a free space optical region (120, 220); one or more input optical waveguides (110, 210) end connected to the free space optical region (120, 220) along a first surface thereof; and one or more output optical waveguides (130, 230) end connected to the free space optical region (120, 220) along a second surface thereof, the second surface facing the first surface; wherein the set of input and output optical waveguides (110, 210, 130, 230) includes at least three optical waveguides, wherein at least one of the one or more input optical waveguides supports multi-mode propagation and includes an offset at joined ends of an input portion and an output portion thereof, the output portion end connecting to the first surface; and wherein the offset is adapted to cause an oscillating mode in the at least one of the one or more input optical waveguides such that the oscillating mode moves transversely in a zig-zag pattern along a length of the one of the one or more input optical waveguides.