A quinuclidine ester of 1-azaheterocyclylacetic acid of general formula wherein: A may be a single bond, double bond, O, S, SO, SO2, NR 3, C(R 3)R 4, CO, C N(R 3), N(R 3)C O, SO 2 N(R 3), N(R 3)C, OC N(R 3), N(R 3)SO 2, C(R 3)=C(R 4) and C(R 3)-(CH 2)-C(R 4); m is an integer from 1 to 4; n is 0 or an integer from 1 to 4; R1 is selected from the group consisting of (C 1 -C 10)-alkyl, aryl, (C 3 -C 8)-cycloalkyl, heteroaryl, aryl(C 1 -C 6)alkyl and heteroaryl(C 1 -C 6)alkyl, optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo (=O), SH, NO 2, CN, CON(R 3) 2, COOH, CO 2 R 3, CF 3, (C 1 -C 10)-alkoxycarbonyl, (C 1 -C 10)-alkylsulfanyl, (C 1 -C 10)-alkylsulfinyl, (C 1 -C 10)-alkylsulfonyl, (C 1 -C 10)-alkyl, (C 1 -C 10)-alkoxyl, aryloxy and heteroaryl; X - is a physiologically acceptable anion; R2 is a group of formula ---(CH 2)p---P---(CH 2)q---W wherein p is 0 or an integer from 1 to 4; q is 0 or an integer from 1 to 4; P is absent or is selected from the group consisting of O, S, SO, SO 2, CO, NR 3, CH=CH, N(R 3)SO 2, N(R 3)COO, N(R 3)C, SO 2 N(R 3), OC N(R 3) and C N(R 3); W is selected from the group consisting of H, (C 1 -C 10)-alkyl, (C 1 -C 10)-alkoxyl, (C 3 -C 8)-cycloalkyl, aryl, heteroaryl, (C 5 -C 10)heterocycloalkyl, optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo (=O), SH, NO 2, CN, CON(R 3) 2, COOH, NH 2, NHCOR 3, CO 2 R 3, (C 1 -C 10)-alkoxycarbonyl, (C 1 -C 10)-alkylsulfanyl, (C 1 -C 10)-alkylsulfinyl, (C 1 -C 10)-alkylsulfonyl, (C 1 -C 10)-alkyl, (C 1 -C 10)-alkoxyl, (C 1 -C 10)alkanoyl and aryl; R3 and R4 are independently selected from the group consisting of H, halogen atoms, CONH 2, (C 1 -C 10)alkyl, (C 2 -C 6)alkynyl, (C 2 -C 6)alkenyl, (C 1 -C 10)alkanoyl, (C 3 -C 8)cycloalkyl, heteroaryl, and aryl optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo (=O), SH, NO 2, CN, CONH 2, COOH, (C 1 -C 10)-alkoxycarbonyl, (C 1 -C 10)-alkylsulfanyl, (C 1 -C 10)-alkylsulfinyl, (C 1 -C 10)-alkylsulfonyl, (C 1 -C 10)-alkyl, (C 1 -C 10)-alkoxyl and (C 3 -C 7)-cycloalkyl. A may be a single bond, double bond, O, S, SO, SO2, NR 3, C(R 3)R 4, CO, C N(R 3), N(R 3)C O, SO 2 N(R 3), N(R 3)C, OC N(R 3), N(R 3)SO 2, C(R 3)=C(R 4) and C(R 3)-(CH 2)-C(R 4); m is an integer from 1 to 4; n is 0 or an integer from 1 to 4; R1 is selected from the group consisting of (C 1 -C 10)-alkyl, aryl, (C 3 -C 8)-cycloalkyl, heteroaryl, aryl(C 1 -C 6)alkyl and heteroaryl(C 1 -C 6)alkyl, optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo (=O), SH, NO 2, CN, CON(R 3) 2, COOH, CO 2 R 3, CF 3, (C 1 -C 10)-alkoxycarbonyl, (C 1 -C 10)-alkylsulfanyl, (C 1 -C 10)-alkylsulfinyl, (C 1 -C 10)-alkylsulfonyl, (C 1 -C 10)-alkyl, (C 1 -C 10)-alkoxyl, aryloxy and heteroaryl; X - is a physiologically acceptable anion; R2 is a group of formula ---(CH 2)p---P---(CH 2)q---W wherein p is 0 or an integer from 1 to 4; q is 0 or an integer from 1 to 4; P is absent or is selected from the group consisting of O, S, SO, SO 2, CO, NR 3, CH=CH, N(R 3)SO 2, N(R 3)COO, N(R 3)C, SO 2 N(R 3), OC N(R 3) and C N(R 3); W is selected from the group consisting of H, (C 1 -C 10)-alkyl, (C 1 -C 10)-alkoxyl, (C 3 -C 8)-cycloalkyl, aryl, heteroaryl, (C 5 -C 10)heterocycloalkyl, optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo (=O), SH, NO 2, CN, CON(R 3) 2, COOH, NH 2, NHCOR 3, CO 2 R 3, (C 1 -C 10)-alkoxycarbonyl, (C 1 -C 10)-alkylsulfanyl, (C 1 -C 10)-alkylsulfinyl, (C 1 -C 10)-alkylsulfonyl, (C 1 -C 10)-alkyl, (C 1 -C 10)-alkoxyl, (C 1 -C 10)alkanoyl and aryl; R3 and R4 are independently selected from the group consisting of H, halogen atoms, CONH 2, (C 1 -C 10)alkyl, (C 2 -C 6)alkynyl, (C 2 -C 6)alkenyl, (C 1 -C 10)alkanoyl, (C 3 -C 8)cycloalkyl, heteroaryl, and aryl optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo (=O), SH, NO 2, CN, CONH 2, COOH, (C 1 -C 10)-alkoxycarbonyl, (C 1 -C 10)-alkylsulfanyl, (C 1 -C 10)-alkylsulfinyl, (C 1 -C 10)-alkylsulfonyl, (C 1 -C 10)-alkyl, (C 1 -C 10)-alkoxyl and (C 3 -C 7)-cycloalkyl. p is 0 or an integer from 1 to 4; q is 0 or an integer from 1 to 4; P is absent or is selected from the group consisting of O, S, SO, SO 2, CO, NR 3, CH=CH, N(R 3)SO 2, N(R 3)COO, N(R 3)C, SO 2 N(R 3), OC N(R 3) and C N(R 3); W is selected from the group consisting of H, (C 1 -C 10)-alkyl, (C 1 -C 10)-alkoxyl, (C 3 -C 8)-cycloalkyl, aryl, heteroaryl, (C 5 -C 10)heterocycloalkyl, optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo (=O), SH, NO 2, CN, CON(R 3) 2, COOH, NH 2, NHCOR 3, CO 2 R 3, (C 1 -C 10)-alkoxycarbonyl, (C 1 -C 10)-alkylsulfanyl, (C 1 -C 10)-alkylsulfinyl, (C 1 -C 10)-alkylsulfonyl, (C 1 -C 10)-alkyl, (C 1 -C 10)-alkoxyl, (C 1 -C 10)alkanoyl and aryl; R3 and R4 are independently selected from the group consisting of H, halogen atoms, CONH 2, (C 1 -C 10)alkyl, (C 2 -C 6)alkynyl, (C 2 -C 6)alkenyl, (C 1 -C 10)alkanoyl, (C 3 -C 8)cycloalkyl, heteroaryl, and aryl optionally substituted by one or more substituents selected from the group consisting of halogen atoms, OH, oxo (=O), SH, NO 2, CN, CONH 2, COOH, (C 1 -C 10)-alkoxycarbonyl, (C 1 -C 10)-alkylsulfanyl, (C 1 -C 10)-alkylsulfinyl, (C 1 -C 10)-alkylsulfonyl, (C 1 -C 10)-alkyl, (C 1 -C 10)-alkoxyl and (C 3 -C 7)-cycloalkyl.