mhurhangee/ep-ind-claims huggingface dataset:
A medical system for electrical stimulation therapy comprising: an implantable lead (350A, 350B, 450A, 450B, 550A, 550B, 650) with multiple levels of lead electrodes in a first segmented electrode configuration, at least one level of the lead electrodes (388, 380, 384, 392, 588, 580, 584, 592) comprising segmented electrodes, the implantable lead extending from a proximal end to a distal end; and a flexible member (340, 440, 540, 640, 740, 840, 940, 1040) configured to be disposed over the first electrode segmented electrode configuration, the flexible member having a first inner side and a first set of member electrodes, at least some of the first set of member electrodes configured to be positioned to electrically contact corresponding lead electrodes of the first segmented electrode configuration, the flexible member having a second outer side and a second set of member electrodes (354, 454, 554, 696A-D, 754, 844, 944, 1044) in a second segmented electrode configuration which is different than the first segmented electrode configuration, at least some of the second set of member electrodes (354, 454, 554, 696A-D, 754, 844, 944, 1044) electrically coupled to corresponding member electrodes of the first set of member electrodes. an implantable lead (350A, 350B, 450A, 450B, 550A, 550B, 650) with multiple levels of lead electrodes in a first segmented electrode configuration, at least one level of the lead electrodes (388, 380, 384, 392, 588, 580, 584, 592) comprising segmented electrodes, the implantable lead extending from a proximal end to a distal end; and a flexible member (340, 440, 540, 640, 740, 840, 940, 1040) configured to be disposed over the first electrode segmented electrode configuration, the flexible member having a first inner side and a first set of member electrodes, at least some of the first set of member electrodes configured to be positioned to electrically contact corresponding lead electrodes of the first segmented electrode configuration, the flexible member having a second outer side and a second set of member electrodes (354, 454, 554, 696A-D, 754, 844, 944, 1044) in a second segmented electrode configuration which is different than the first segmented electrode configuration, at least some of the second set of member electrodes (354, 454, 554, 696A-D, 754, 844, 944, 1044) electrically coupled to corresponding member electrodes of the first set of member electrodes.
A multilevel converter having an alternating current, AC, side and a Direct Current, DC, side and being configured to convert between AC and DC and comprising at least two converter blocks (CB1, CB2) connected in series between a first and a second DC terminal (DC1, DC2), wherein each converter block (CB1, CB2) comprises a number of parallel valve arm strings (VASA1, VASB1, VASC1, VASA2, VASB2, VASC2), where each valve arm string comprises an upper valve arm (VAUA1, VAUB1, VAUC1, VAUA2, VAUB2, VAUC2) connected in series with a lower valve arm (VALA1, VALB1, VALC1, VALA2, VALB2, VALC2) having a number of converter cells connected in cascade, a midpoint between the upper and lower valve arm (VAUA1, VALA1, VAUB1, VALB1, VAUC1, VALC1) of a valve arm string (VASA1, VASB1, VASC1) in the first converter block is connected to a corresponding primary AC terminal (ACA1, ACB1, ACC1) and a midpoint between the upper and lower valve arm (VAUA2, VALA2, VAUB2, VALB2, VAUC2, VALC2) in a corresponding valve arm string (VASA2, VASB2, VASC2) of the second converter block is connected to a corresponding secondary AC terminal (ACA2, ACB2, ACC2), characterised by a chopper circuit connected between the converter blocks (CB1, CB2), wherein the chopper circuit comprises a power dissipating element in parallel with a circuit breaker, and the multilevel converter is arranged to dissipate energy received via the AC terminals upon the detection of a fault at one of the sides, where, in order to obtain said energy dissipation and upon the detection of said fault, at least one set of valve arms connected to the DC terminals, is controlled to reduce the fault current from the DC side to zero and the converter when dissipating the energy received via the AC terminals is arranged to control the lower valve arms (VALA1, VALB1, VALC1) of the first converter block and the upper valve arms (VAUA2, VAUB2, VAUC2) of the second converter block to reduce the current through the chopper circuit to a level at which circuit breaker operation may be performed, the circuit breaker of the chopper circuit being controlled to open during said circuit breaker operation, and the lower valve arms (VALA1, VALB1, VALC1) of the first converter block and the upper valve arms (VAUA2, VAUB2, VAUC2) of the second converter block being controlled to let a current originating on the AC side of the converter dissipate through the power dissipating element of the chopper circuit.
A viral expression vector encoding a therapeutic protein for use in a method of treating an ophthalmic condition in a subject by intraocular injection of the viral expression vector and application of electric current to the eye.
A paper, in particular for use in the manufacture of corrugated board, the paper being formed from at least two layers of different composition which are calendered to one another, and the paper containing waste paper fibres and grass fibres, the grass fibres being fibres of fresh and/or sour grass and/or sea grass and/or algae, characterised in that a first layer of the paper is designed as a supporting layer and contains waste paper fibres and a maximum proportion of grass fibres of 30% by weight or no grass fibres, and in that a second layer of the paper forms a top layer which contains waste paper fibres and other fibres in the form of waste paper fibres, the top layer forming a top layer which contains grass fibres and other fibres in the form of waste paper fibres or no grass fibres, and that a second layer of the paper forms a top layer containing grass fibres and other fibres in the form of waste paper fibres, wherein the top layer contains a minimum proportion of grass fibres of 20% by weight and a maximum proportion of waste paper fibres of 80% by weight and wherein the proportion of grass fibres in the top layer is higher than the proportion of grass fibres in the base layer.
A spark plug which includes a ground electrode having a proximal end section fixed to a metallic shell, a bent section formed integral with the proximal end section, and a distal end section formed integral with the bent section and adapted to form a spark discharge gap g in cooperation with a center electrode and in which the ground electrode is configured to have a core portion extending from the proximal end section toward the distal end section via the bent section, a heat transfer portion extending from the proximal end section toward the distal end section via the bent section, and an external layer located externally of the core portion and the heat transfer portion and extending from the proximal end section to the distal end section via the bent section, the external layer is formed from a first metal being excellent in heat resistance and corrosion resistance, the heat transfer portion is formed from a second metal higher in thermal conductivity than the first metal, the core portion is formed from a third metal higher in hardness than the second metal, and the second metal is higher in linear thermal expansion coefficient than the first metal and the third metal, characterised in that, as viewed on a section of the ground electrode taken orthogonally to a direction along which the ground electrode extends, at least at an intermediate position January 2015 of the bent section with respect to the direction, a center of the core portion is offset toward the center electrode from a center of the heat transfer portion.
A compound having the structure: wherein A is a first polypeptide component of the compound; wherein C is a second polypeptide component of the compound, which polypeptide component has at its N-terminus a sequence of amino acids selected from the group consisting of a cysteine, selenocysteine, CP, CPXCP (where X = P, R, or S), CDKTHTCPPCP, CVECPPCP, CCVECPPCP and CDTPPPCPRCP, and comprises consecutive amino acids which (i) are identical to a stretch of consecutive amino acids present in a chain of an F c domain of an antibody; and (ii) bind to an F c receptor, wherein B is a chemical structure linking A and C; wherein the dashed line between B and C represents a peptidyl linkage between B and the N-terminus of C; wherein the solid line between A and B represents a nonpeptidyl linkage comprising the structure: or wherein R 1 is H or is part of an additional structure that is a cyclic structure, wherein the additional cyclic structure comprises R 1 or a portion of R 1, and may also comprise R 2 or a portion of R 2, and the carbon between R 2 and the alkene double bond. wherein A is a first polypeptide component of the compound; wherein C is a second polypeptide component of the compound, which polypeptide component has at its N-terminus a sequence of amino acids selected from the group consisting of a cysteine, selenocysteine, CP, CPXCP (where X = P, R, or S), CDKTHTCPPCP, CVECPPCP, CCVECPPCP and CDTPPPCPRCP, and comprises consecutive amino acids which (i) are identical to a stretch of consecutive amino acids present in a chain of an F c domain of an antibody; and (ii) bind to an F c receptor, wherein B is a chemical structure linking A and C; wherein the dashed line between B and C represents a peptidyl linkage between B and the N-terminus of C; wherein the solid line between A and B represents a nonpeptidyl linkage comprising the structure: or wherein R 1 is H or is part of an additional structure that is a cyclic structure, wherein the additional cyclic structure comprises R 1 or a portion of R 1, and may also comprise R 2 or a portion of R 2, and the carbon between R 2 and the alkene double bond.
A current mirror circuit adapted to balance respective currents in a plurality of parallel circuit branches forming at least part of a target circuit, the current mirror circuit including: a plurality of balancing transistors, each having a collector, an emitter, and a base, the collector and emitter of each balancing transistor connected in series with a respective circuit branch; a selection circuit adapted to connect the circuit branch having the smallest current amongst the circuit branches to the bases of each balancing transistor; and an isolation circuit, characterised in that the isolation circuit includes a plurality of fault detection logic circuits, each corresponding to a respective circuit branch and adapted to respectively detect whether there is an open circuit fault in the respective circuit branch, the isolation circuit also including a plurality of isolation switches, each corresponding to a respective balancing transistor and adapted to be opened so as to disconnect the base of the balancing transistor corresponding to the circuit branch in which an open circuit fault is detected from the circuit branch having the smallest current amongst the circuit branches, thereby allowing the isolation circuit to isolate the circuit branch having an open circuit fault from the rest of the target circuit. a plurality of balancing transistors, each having a collector, an emitter, and a base, the collector and emitter of each balancing transistor connected in series with a respective circuit branch; a selection circuit adapted to connect the circuit branch having the smallest current amongst the circuit branches to the bases of each balancing transistor; and an isolation circuit, characterised in that the isolation circuit includes a plurality of fault detection logic circuits, each corresponding to a respective circuit branch and adapted to respectively detect whether there is an open circuit fault in the respective circuit branch, the isolation circuit also including a plurality of isolation switches, each corresponding to a respective balancing transistor and adapted to be opened so as to disconnect the base of the balancing transistor corresponding to the circuit branch in which an open circuit fault is detected from the circuit branch having the smallest current amongst the circuit branches, thereby allowing the isolation circuit to isolate the circuit branch having an open circuit fault from the rest of the target circuit.
A dialysis machine comprising a balancing system that has at least one balancing chamber for a volumetrically exact supply and removal of dialysis solution to and from a dialyzer fluidically connected to the balancing system in operation; a water inlet system connected to the balancing system for the supply of fresh dialysis liquid, with the water inlet system having an apparatus for degassing water that is connected to an air separator of the dialysis machine, with a first part region of the air separator serving as a mixing chamber and being connectable to at least one concentrate source (K1, K2) via at least one concentrate line (54, 56) and being in fluid communication with the balancing system via at least one dialyzate line, characterized in that the filling volume of a balancing chamber corresponds to or exceeds the sum of the volume of the mixing chamber and the inner volume of the dialyzate line.
A method for producing a reactive polyurethane composition, comprising the steps of - in a first method step, preparing a monomer-free thermoplastic polyurethane having isocyanate-reactive groups from an isocyanate-reactive polymer or from a mixture of isocyanate-reactive polymers having a fraction of at least 90 wt% of linear molecules by reaction with a polyisocyanate having a molecular weight of < 500 g/mol with a molar deficit of the isocyanate groups of the polyisocyanate relative to the isocyanate-reactive end groups of the polymer or of the mixture of polymers, and - in a second method step, reacting said thermoplastic polyurethane with a low-monomer-content isocyanate-terminal prepolymer having a residual monomer content of not greater than 0.5 wt%, in a molar ratio of the isocyanate-reactive end groups of the thermoplastic polyurethane to the isocyanate groups of the prepolymer of 1:1.1 to 1:5 to give the polyurethane composition comprising reactive isocyanate groups, where the method takes place with addition of an inorganic filler component and optionally of auxiliaries and the filler component comprises particles of at least one filler which have a Mohs hardness of at least 6, and where the reactive polyurethane composition has a viscosity of 2000 mPas to 100 000 mPas at 120°C. - in a first method step, preparing a monomer-free thermoplastic polyurethane having isocyanate-reactive groups from an isocyanate-reactive polymer or from a mixture of isocyanate-reactive polymers having a fraction of at least 90 wt% of linear molecules by reaction with a polyisocyanate having a molecular weight of < 500 g/mol with a molar deficit of the isocyanate groups of the polyisocyanate relative to the isocyanate-reactive end groups of the polymer or of the mixture of polymers, and - in a second method step, reacting said thermoplastic polyurethane with a low-monomer-content isocyanate-terminal prepolymer having a residual monomer content of not greater than 0.5 wt%, in a molar ratio of the isocyanate-reactive end groups of the thermoplastic polyurethane to the isocyanate groups of the prepolymer of 1:1.1 to 1:5 to give the polyurethane composition comprising reactive isocyanate groups,
Use of an acrylic composition comprising a melt blend of a thermoplastic high molecular weight acrylic material (HMWA) and a thermoplastic low molecular weight acrylic material (LMWA), at least 70% w/w, based on the total weight of the HMWA, of the said HMWA comprising an alkyl (alk)acrylate (co)polymer, the said (co)polymer comprising at least 80% w/w of a first polymer unit derived from C 1 -C 12 alkyl (C 1 -C 8 alk) acrylate monomer units and optionally, up to 20% w/w, based on the said alkyl (alk)acrylate (co) polymer of a first copolymer unit derived from C 1 -C 12 alkyl(C 0 -C 8 alk) acrylate and/or (C 0 -C 8 alk)acrylic acid monomer units, the said HMWA having a weight average molecular weight of between 40k Daltons and 1000k Daltons, at least 70% w/w, based on the total weight of the LMWA, of the said LMWA comprising an alkyl (alk) acrylate (co)polymer, the said (co)polymer comprising at least 80% w/w of a second polymer unit derived from C 1 -C 12 alkyl (C 1 -C 8 alk)acrylate monomer units and optionally, up to 20% w/w, based on the said alkyl (alk) acrylate (co)polymer of a second copolymer unit derived from C 1 -C 12 alkyl (C 0 -C 8 alk) acrylate and/or (C 0 -C 8 alk)acrylic acid monomer units, the said LMWA having a weight average molecular weight of between the entanglement molecular weight (M e) (expressed in k Daltons) and 250k Daltons, with the proviso that the HMWA has a higher Mw than the LMWA, to provide a high Tg melt blended composition or moulded polymer product, wherein the product is optionally impact modified.
A transdermal pharmaceutical formulation comprising progesterone, wherein the progesterone is solubilized in medium chain fatty acid esters, and wherein the progesterone is present in a transdermal patch; the pharmaceutical formulation being: (i) 7.14% w/w progesterone, 0.29% w/w 17-β estradiol, hemihydrate 82.57% w/w monoglycerides/diglycerides/triglycerides of caprylic and capric acid (e.g., Capmul MCM), and 10.0% w/w lauroyl polyoxy-32-glycerides (e.g., Gelucire 44/14); (ii) 7.34% w/w progesterone, 1.2% w/w 17-β estradiol, hemihydrate and 91.46% w/w monoglycerides/diglycerides/triglycerides of caprylic and capric acid (e.g., Capmul MCM); or (iii) 9.50% w/w progesterone, 1.2% w/w 17-β estradiol, hemihydrate and 89.30% w/w propylene glycol monocaprylate (e.g., Capmul PG8). (i) 7.14% w/w progesterone, 0.29% w/w 17-β estradiol, hemihydrate 82.57% w/w monoglycerides/diglycerides/triglycerides of caprylic and capric acid (e.g., Capmul MCM), and 10.0% w/w lauroyl polyoxy-32-glycerides (e.g., Gelucire 44/14); (ii) 7.34% w/w progesterone, 1.2% w/w 17-β estradiol, hemihydrate and 91.46% w/w monoglycerides/diglycerides/triglycerides of caprylic and capric acid (e.g., Capmul MCM); or (iii) 9.50% w/w progesterone, 1.2% w/w 17-β estradiol, hemihydrate and 89.30% w/w propylene glycol monocaprylate (e.g., Capmul PG8).
An access system for disabled persons comprising; • A lower level platform • A sloped platform • A hinged connection between a higher level and a sloped platform, and • Lifting and lowering means. and characterized in that, • It has hinged connection between the lower level platform and the sloped platform in order to keep horizontal position of the lower level platform during the lifting and lowering operations, and • it has an adjustable hinge joint of side guiderails which can be moved between a fixed position and an adjusting position (A'), an adjustable hinge joint of the sloped platform which can be moved between a fixed position and an adjusting position (B'), an adjustable hinge joint of a hydraulic-pneumatic piston which can be moved between a fixed position and an adjusting position (C') and an adjustable hinge joint of a scissor lift mechanism which can be moved between a fixed position and an adjusting position (D'). • A lower level platform • A sloped platform • A hinged connection between a higher level and a sloped platform, and • Lifting and lowering means. and characterized in that, • It has hinged connection between the lower level platform and the sloped platform in order to keep horizontal position of the lower level platform during the lifting and lowering operations, and • it has an adjustable hinge joint of side guiderails which can be moved between a fixed position and an adjusting position (A'), an adjustable hinge joint of the sloped platform which can be moved between a fixed position and an adjusting position (B'), an adjustable hinge joint of a hydraulic-pneumatic piston which can be moved between a fixed position and an adjusting position (C') and an adjustable hinge joint of a scissor lift mechanism which can be moved between a fixed position and an adjusting position (D').
A linear compressor, comprising: a shell; a cylinder provided in the shell to define a compression space for a refrigerant; a piston reciprocated in an axial direction within the cylinder; a discharge valve provided at one end of the cylinder to selectively discharge the refrigerant compressed in the compression space; and at least one nozzle provided disposed in the cylinder and through which at least a portion of the refrigerant discharged through the discharge valve is flowable, wherein the at least one nozzle comprises an inlet, through which the refrigerant is introduced, and an outlet having a diameter less than a diameter of the inlet, wherein the linear compressor further comprises: at least one gas inflow recessed from an outer circumferential surface of the cylinder, wherein the least one gas inflow communicates with the at least one nozzle; and a filter member disposed in the at least one gas inflow, characterized in that the filter member comprises a thread that is wound several times around the at least one gas inflow. a shell; a cylinder provided in the shell to define a compression space for a refrigerant; a piston reciprocated in an axial direction within the cylinder; a discharge valve provided at one end of the cylinder to selectively discharge the refrigerant compressed in the compression space; and at least one nozzle provided disposed in the cylinder and through which at least a portion of the refrigerant discharged through the discharge valve is flowable, wherein the at least one nozzle comprises an inlet, through which the refrigerant is introduced, and an outlet having a diameter less than a diameter of the inlet, wherein the linear compressor further comprises: at least one gas inflow recessed from an outer circumferential surface of the cylinder, wherein the least one gas inflow communicates with the at least one nozzle; and a filter member disposed in the at least one gas inflow, characterized in that the filter member comprises a thread that is wound several times around the at least one gas inflow. at least one gas inflow recessed from an outer circumferential surface of the cylinder, wherein the least one gas inflow communicates with the at least one nozzle; and a filter member disposed in the at least one gas inflow, characterized in that the filter member comprises a thread that is wound several times around the at least one gas inflow.