mhurhangee/ep-ind-claims huggingface dataset:
A method for conditioning an organ with a view to transplantation, comprising the following steps in succession: - flushing the organ, and - preserving the organ in a normal-potassium solution which has a potassium concentration of less than 10 mM and comprises a quantity in the range 15 to 20 g/L of polyethylene glycol with a molecular weight of 20 000 Da, characterized in that the flushing is carried out with a solution with a composition which is identical to that used in the preservation step, said solution having a viscosity in the range 0.8 to 1.4 mm2/s at 20°C. - flushing the organ, and - preserving the organ in a normal-potassium solution which has a potassium concentration of less than 10 mM and comprises a quantity in the range 15 to 20 g/L of polyethylene glycol with a molecular weight of 20 000 Da,
A method of performing rapid nucleic acid detection, comprising the steps of: (a) obtaining a sample comprising a target nucleic acid molecule; (b) mixing the target nucleic acid molecule with (i) a first probe that will bind to the nucleic acid molecule, and (ii) a second agent that will bind to the first probe, thereby forming a nucleic acid molecule complex in solution, wherein the nucleic acid molecule complex comprises the first probe and the second agent, the second agent comprising a signal generating labeling tag or an enzyme-linked conjugate; (c) applying in a flow through manner the solution comprising the nucleic acid molecule complex to an array comprising a third probe that will bind to the complex, thereby capturing the nucleic acid complex on the array; and (d) detecting the captured nucleic acid molecule on the array. (a) obtaining a sample comprising a target nucleic acid molecule; (b) mixing the target nucleic acid molecule with (i) a first probe that will bind to the nucleic acid molecule, and (ii) a second agent that will bind to the first probe, thereby forming a nucleic acid molecule complex in solution, wherein the nucleic acid molecule complex comprises the first probe and the second agent, the second agent comprising a signal generating labeling tag or an enzyme-linked conjugate; (c) applying in a flow through manner the solution comprising the nucleic acid molecule complex to an array comprising a third probe that will bind to the complex, thereby capturing the nucleic acid complex on the array; and (d) detecting the captured nucleic acid molecule on the array.
A method of identifying a candidate treatment for a cancer in a subject in need thereof, comprising performing DNA sequencing on a sample obtained from the subject to determine a sequencing mutation profile on a group of genes comprising KRAS, BRAF, c-KIT and EGFR.
Method for displaying a target vehicle opening fore zone for a potential, future vehicle user of an automated vehicle by means of a controller, wherein the target vehicle opening fore zone for the potential, future vehicle user is indicated by means of at least one actuator of the automated vehicle that is actuatable by the controller during the journey to the potential, future vehicle user before a stopping position is reached and after the potential, future vehicle user of the automated vehicle was identified outside of the automated vehicle.
A lighting device comprising a light source and a light converter, wherein the light source is configured to provide light source light, wherein the light converter comprises (a) a donor luminescent material able to convert at least part of the first light source light into donor light, and (b) a acceptor luminescent material, wherein the donor luminescent material and acceptor luminescent material are configured as donor-acceptor luminescent materials (210,220) which, upon excitation of the donor luminescent material by the light source light provide acceptor light having an acceptor light spectral distribution different from a donor light spectral distribution of the donor light, wherein the light converter further comprises (c) a periodic plasmonic antenna array, and wherein the lighting device (1000 is configured to provide lighting device light comprising said donor light and said acceptor light characterized in that the plasmonic antenna array is configured to enhance the generation of said donor light.
A process for obtaining an implant with a biocompatible polymer coating, said process comprising: (a) dipping the implant in a solution of biocompatible polymer to obtain an implant with a dip coating; and (b) immediately electrospinning the same polymer onto the implant with dip coating of step (a) to obtain an implant with a biocompatible polymer coating; wherein, fibres of the biocompatible polymer are partially embedded into the dip coating, and said coating remains intact/independent of cracks/tears even after application of mechanical forces selected from the group consisting of bending, tensile stress, compression, and torsion, wherein said biocompatible polymer is silk fibroin. (a) dipping the implant in a solution of biocompatible polymer to obtain an implant with a dip coating; and (b) immediately electrospinning the same polymer onto the implant with dip coating of step (a) to obtain an implant with a biocompatible polymer coating; wherein, fibres of the biocompatible polymer are partially embedded into the dip coating, and said coating remains intact/independent of cracks/tears even after application of mechanical forces selected from the group consisting of bending, tensile stress, compression, and torsion, wherein said biocompatible polymer is silk fibroin.
A method for evaluating whether a subject having RIFLE stage I or F acute kidney injury will recover, comprising: performing an assay method configured to detect Chitinase-3-like protein 1 on a urine sample obtained from the subject to provide an assay result comprising a measured concentration of Chitinase-3-like protein 1; and assessing whether the subject is likely to recover to RIFLE stage of 0 or R within 7 days, 72 hours, 48 hours, 24 hours or 12 hours after the sample was obtained by comparing the assay result to a predetermined threshold selected from a population study, wherein an increased likelihood of recovery is assigned to the subject when the assay result is below the threshold, relative to a likelihood of recovery assigned when the assay result is above the threshold. performing an assay method configured to detect Chitinase-3-like protein 1 on a urine sample obtained from the subject to provide an assay result comprising a measured concentration of Chitinase-3-like protein 1; and assessing whether the subject is likely to recover to RIFLE stage of 0 or R within 7 days, 72 hours, 48 hours, 24 hours or 12 hours after the sample was obtained by comparing the assay result to a predetermined threshold selected from a population study, wherein an increased likelihood of recovery is assigned to the subject when the assay result is below the threshold, relative to a likelihood of recovery assigned when the assay result is above the threshold.
A device for packaging and dispensing a generally liquid or viscous product, comprising a container for containing the product to be packaged and dispensed in the form of clean or sterile measured doses or drops by means of a dispensing accessory including a tip, wherein the assembly of container and accessory comprises a product dosing chamber, supplied with product from the container by a first non-return valve, and in communication with outside the device by means of a second non-return valve in order to dispense a measured dose or drop of product, when said accessory is actuated, characterized in that it additionally comprises a flexible and deformable supplemental chamber, actuatable simultaneously with said closing chamber and enabling to either suction a residual drop present at the end of said accessory after the dispensing of a measured dose or drop, or blow said residual drop, or blow said measured dose or drop without permitting the formation of a residual drop.
An antisense oligonucleotide comprising at least one modification that is incorporated between two bases of the antisense oligonucleotide, wherein the modification increases binding affinity and nuclease resistance of the antisense oligonucleotide, and wherein the modification has the structure: wherein the linking groups L 1 and L 2 positioning the modification at an internal position of the oligonucleotide are independently an alkyl, alkynyl, alkenyl, heteroalkyl, substituted alkyl, aryl, heteroaryl, substituted aryl, cycloalkyl, alkylaryl, or alkoxy groups; R 1, R 2, R 4, R 5 are independently a hydrogen, alkyl, alkynyl, alkenyl, heteroalkyl, substituted alkyl, aryl, heteroaryl, substituted aryl, cycloalkyl, alkylaryl, alkoxy, an electron withdrawing group, or an electron donating group; R 6, R 7, R 9 -R 12 are independently a hydrogen, alkyl, alkynyl, alkenyl, heteroalkyl, substituted alkyl, aryl, heteroaryl, substituted aryl, cycloalkyl, alkylaryl, alkoxy, an electron withdrawing group, or an electron donating group; R 8 is a hydrogen, alkyl, alkynyl, alkenyl, heteroalkyl, substituted alkyl, aryl, heteroaryl, substituted aryl, cycloalkyl, alkylaryl, alkoxy, or an electron withdrawing group; and X is a nitrogen or carbon atom, wherein if X is a carbon atom, the fourth substituent attached to the carbon atom can be hydrogen or a C1-C8 alkyl group.
A seismic transducer apparatus for inducing energy waves in an elastic medium comprising: a frame; a baseplate attached to the frame, the baseplate having a flat lower surface for engagement of a surface of an elastic medium, the flat lower surface having a perimeter, wherein the perimeter is in the form of a polygon, wherein the polygon comprises at least eight sides, optionally between 8 and 10 sides; a reaction mass supported by the frame; and a driver configured to actuate the reaction mass in a reciprocating motion so as to impart vibratory energy to the baseplate. a frame; a baseplate attached to the frame, the baseplate having a flat lower surface for engagement of a surface of an elastic medium, the flat lower surface having a perimeter, wherein the perimeter is in the form of a polygon, wherein the polygon comprises at least eight sides, optionally between 8 and 10 sides; a reaction mass supported by the frame; and a driver configured to actuate the reaction mass in a reciprocating motion so as to impart vibratory energy to the baseplate.
A computer implemented method for deblending seismic data obtained when surveying an underground formation, the method comprising: receiving blended seismic data gathered using simultaneous source acquisition; applying a first deblending technique, FDT, to the blended seismic data to calculate a signal model and a noise model; calculating residual data by subtracting (i) data corresponding to the signal model and the noise model from (ii) the blended seismic data; applying a second deblending technique, SDT, to the residual data resulting after applying the FDT; and creating an image of the explored underground formation using deblended data obtained by applying the FDT and the SDT, wherein the FDT and the SDT are different techniques. receiving blended seismic data gathered using simultaneous source acquisition; applying a first deblending technique, FDT, to the blended seismic data to calculate a signal model and a noise model; calculating residual data by subtracting (i) data corresponding to the signal model and the noise model from (ii) the blended seismic data; applying a second deblending technique, SDT, to the residual data resulting after applying the FDT; and creating an image of the explored underground formation using deblended data obtained by applying the FDT and the SDT, wherein the FDT and the SDT are different techniques.
Hydrogel formulations of oxidized dextrin reticulated with adipic acid dihydrazide comprising the following structure: which possess the capacity of embodiment within its three-dimensional porous, wherein said dextrin has a molecular weight between 1200 and 8000 Da.
An exposure apparatus for exposing a substrate with an illumination light through liquid (Lm 1, Lm 2), comprising: a stage (9, 10) for holding the substrate; an illumination optical system for illuminating a pattern with the illumination light; a projection optical system for projecting an image of the illuminated pattern onto the substrate through the liquid; and a driving system for driving the stage so that in a scanning exposure of the substrate, the substrate is moved relative to the illumination light with respect to a first direction perpendicular to an optical axis of the projection optical system, wherein the projection optical system comprises a refractive optical element (Lp, Lb) having a light emitting surface (Lpb), through a part of which the illumination light passes in use and which is arranged nearest to an imaging plane of the projection optical system to contact the liquid in use, characterised in that the refractive optical element has a protruding portion formed in a light emitting side of the refractive optical element so as to extend toward the imaging plane with respect to a surrounding portion other than the protruding portion and being bounded by the light emitting surface (Lpb) and a surface (Lpc) that extends from the light emitting surface toward a light entering side of the optical element, and in that the protruding portion is formed so that a center (Lpba) of the light emitting surface is decentred from the optical axis with respect to the first direction. a stage (9, 10) for holding the substrate; an illumination optical system for illuminating a pattern with the illumination light; a projection optical system for projecting an image of the illuminated pattern onto the substrate through the liquid; and a driving system for driving the stage so that in a scanning exposure of the substrate, the substrate is moved relative to the illumination light with respect to a first direction perpendicular to an optical axis of the projection optical system, wherein the projection optical system comprises a refractive optical element (Lp, Lb) having a light emitting surface (Lpb), through a part of which the illumination light passes in use and which is arranged nearest to an imaging plane of the projection optical system to contact the liquid in use, characterised in that the refractive optical element has a protruding portion formed in a light emitting side of the refractive optical element so as to extend toward the imaging plane with respect to a surrounding portion other than the protruding portion and being bounded by the light emitting surface (Lpb) and a surface (Lpc) that extends from the light emitting surface toward a light entering side of the optical element, and in that the protruding portion is formed so that a center (Lpba) of the light emitting surface is decentred from the optical axis with respect to the first direction.
An integrated biopsy/access tool for harvesting a biopsy specimen and providing access to a remote anatomical site, comprising: a biopsy device having distal and proximal ends; a cannula having distal and proximal ends, and a first functional channel extending therebetween; a handle means (6, 12, 54), removably coupled to at least the biopsy device or cannula, wherein if the handle means is removed from the biopsy device or cannula, at least a portion of the first functional channel is adapted to telescope over the biopsy device; and a placement means (9, 33, 51) for determining proper placement of at least one of the biopsy device or cannula, characterized in that the placement means (9, 33, 51) is telescopically received within a second functional channel extending through the biopsy device.
A system (100; 200) for smoke detection and indoor air quality monitoring, comprising: two or more light sources (102, 104; 202, 204) configured to emit light into a monitored space, wherein at least two of the two or more light sources emit respective light cones each having a respective symmetry axis, wherein the symmetry axes of the respective light cones intersect one another; one or more light sensing devices (106, 108, 110; 206, 208, 210) configured to receive scattered light; a processor (112; 212) operatively connected to the one or more light sensing devices to evaluate the scattered light for the presence of one or more indoor air quality conditions in the monitored space; and a polarizing filter optically coupled to a respective one of the light sensing devices wherein an airborne particle type is discriminated via the use the polarizing filter. two or more light sources (102, 104; 202, 204) configured to emit light into a monitored space, wherein at least two of the two or more light sources emit respective light cones each having a respective symmetry axis, wherein the symmetry axes of the respective light cones intersect one another; one or more light sensing devices (106, 108, 110; 206, 208, 210) configured to receive scattered light; a processor (112; 212) operatively connected to the one or more light sensing devices to evaluate the scattered light for the presence of one or more indoor air quality conditions in the monitored space; and a polarizing filter optically coupled to a respective one of the light sensing devices wherein an airborne particle type is discriminated via the use the polarizing filter.
A bone, cartilage, and disk removal tool assembly comprising: - a housing, said housing including a guide, said guide being constructed and arranged to guide a shuttle slidably mounted on said guide for reciprocating lateral translation along said guide, said shuttle including a rack portion of a rack-and-pinion mechanism; - a motor mounted in the housing, - a spindle mounted for rotation to the housing, said spindle including a pinion gear secured thereto to be intermeshed with said rack portion; and - said rack-and-pinion mechanism operably driven by the motor and connected to the spindle to oscillate the spindle for providing a rotary oscillating cutting operation characterized in that said motor drives an eccentric drive, said eccentric drive having a pin member offset with respect to a motor shaft that cooperates with a slot in said shuttle to reciprocate said shuttle along said guide during rotation of said motor shaft, a counterbalance secured to said eccentric drive offset from said motor shaft and said pin member. - a housing, said housing including a guide, said guide being constructed and arranged to guide a shuttle slidably mounted on said guide for reciprocating lateral translation along said guide, said shuttle including a rack portion of a rack-and-pinion mechanism; - a motor mounted in the housing, - a spindle mounted for rotation to the housing, said spindle including a pinion gear secured thereto to be intermeshed with said rack portion; and - said rack-and-pinion mechanism operably driven by the motor and connected to the spindle to oscillate the spindle for providing a rotary oscillating cutting operation
A flexible tool system comprising: a tool body with a flexible portion, a proximal end, and a distal end, the tool body defining a channel in the flexible portion; a first optical fiber embedded in the tool body or attached to a wall of the tool body within the flexible portion, the first optical fiber having a first diameter; and an instrument comprising a second optical fiber, the instrument configured to be removably inserted within the channel in the flexible portion, the second optical fiber having a second diameter, the second diameter being larger than the first diameter; wherein the first optical fiber and the second optical fiber are multicore optical fibers, each comprising a peripheral core arranged helically about a central axis and are each configured to sense a shape of the flexible portion. a tool body with a flexible portion, a proximal end, and a distal end, the tool body defining a channel in the flexible portion; a first optical fiber embedded in the tool body or attached to a wall of the tool body within the flexible portion, the first optical fiber having a first diameter; and an instrument comprising a second optical fiber, the instrument configured to be removably inserted within the channel in the flexible portion, the second optical fiber having a second diameter, the second diameter being larger than the first diameter; wherein the first optical fiber and the second optical fiber are multicore optical fibers, each comprising a peripheral core arranged helically about a central axis and are each configured to sense a shape of the flexible portion.
A method comprising: receiving service requirements for one or more wireless devices from the respective wireless devices; evaluating the service requirements corresponding to data to be transmitted to the wireless devices in a first time interval and a second time interval; for the first time interval, allocating first and second non-overlapping portions of a frequency band to first and second multicarrier modulation schemes, respectively, the first and second multicarrier modulation schemes having first and second subcarrier spacings, respectively, the first and second subcarrier spacings differing from one another; and for the second time interval, allocating third and fourth non-overlapping portions of a frequency band to third and fourth multicarrier modulation schemes, respectively, the third and fourth multicarrier modulation schemes having third and fourth subcarrier spacings, respectively, wherein the third and fourth subcarrier spacings differ from one another, wherein the allocating of the first and second portions of the frequency band to the first and second multicarrier modulation schemes for the first time interval and the allocating of the third and fourth portions of the frequency band to the third and fourth multicarrier modulation schemes for the second time interval are based on said evaluating of service requirements, and wherein the third and fourth portions differ from the first and second portions or the third and fourth multicarrier modulation schemes differ from the first and second multicarrier modulation schemes, or both. receiving service requirements for one or more wireless devices from the respective wireless devices; evaluating the service requirements corresponding to data to be transmitted to the wireless devices in a first time interval and a second time interval; for the first time interval, allocating first and second non-overlapping portions of a frequency band to first and second multicarrier modulation schemes, respectively, the first and second multicarrier modulation schemes having first and second subcarrier spacings, respectively, the first and second subcarrier spacings differing from one another; and for the second time interval, allocating third and fourth non-overlapping portions of a frequency band to third and fourth multicarrier modulation schemes, respectively, the third and fourth multicarrier modulation schemes having third and fourth subcarrier spacings, respectively, wherein the third and fourth subcarrier spacings differ from one another, wherein the allocating of the first and second portions of the frequency band to the first and second multicarrier modulation schemes for the first time interval and the allocating of the third and fourth portions of the frequency band to the third and fourth multicarrier modulation schemes for the second time interval are based on said evaluating of service requirements, and wherein the third and fourth portions differ from the first and second portions or the third and fourth multicarrier modulation schemes differ from the first and second multicarrier modulation schemes, or both.