mhurhangee/ep-ind-claims huggingface dataset:
A composition for use in a method for treating an individual in need of treatment having a condition in which HSP60/ClpP expression and/or binding is abnormal, the use comprising administering to the individual in need of treatment a therapeutically effective amount of the composition comprising a compound having the following structure: wherein the condition is a cancer chosen from prostate cancer, leukemia, lung cancer, dermatological cancer, premalignant lesions of the upper digestive tract, malignancies of the brain, malignancies of the breast, and combinations thereof.
A pneumatic radial tire for an aircraft, comprising a bead core including a pair of cable beads, a radial carcass including a plurality of plies toroidally extending between the bead cores, and a stiffener disposed adjacent to the bead core on a tire radial direction outer side of the bead core, the radial carcass comprising one or more turn-up plies (4a-4e) including a windup portion (4aT-4eT) wound up around the bead core from an inner side to an outer side in a tire axial direction, and one or more down plies (5a, 5b) that cover the windup portion (4aT-4eT) and extend to a radial direction inner side of at least the bead core, characterised in that, in tire axial direction cross-sectional view in a state where the tire is mounted to a rim, is not filled with an internal pressure, and is unloaded, when an intersection point of a virtual circle with a ply closest to a tire axial direction inner side of the stiffener among the plies intersecting with the virtual circle having a radius that is twice as large as a diameter D of the bead core from a center corresponding to a center O of the bead core is a point A, an intersection point of the virtual circle with a ply closest to a tire axial direction outer side of the stiffener is a point B, and a midpoint between the point A and the point B is a reference point C, then a line segment OC connecting the center O of the bead core to the reference point C has an inclination angle θ of 17° or less to a tire radial direction line passing the center O of the bead core on the tire axial direction outer side. the radial carcass comprising one or more turn-up plies (4a-4e) including a windup portion (4aT-4eT) wound up around the bead core from an inner side to an outer side in a tire axial direction, and one or more down plies (5a, 5b) that cover the windup portion (4aT-4eT) and extend to a radial direction inner side of at least the bead core, characterised in that, in tire axial direction cross-sectional view in a state where the tire is mounted to a rim, is not filled with an internal pressure, and is unloaded, when an intersection point of a virtual circle with a ply closest to a tire axial direction inner side of the stiffener among the plies intersecting with the virtual circle having a radius that is twice as large as a diameter D of the bead core from a center corresponding to a center O of the bead core is a point A, an intersection point of the virtual circle with a ply closest to a tire axial direction outer side of the stiffener is a point B, and a midpoint between the point A and the point B is a reference point C, then a line segment OC connecting the center O of the bead core to the reference point C has an inclination angle θ of 17° or less to a tire radial direction line passing the center O of the bead core on the tire axial direction outer side.
A compound selected from the group consisting of: 6-tert-butyl-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(morpholine-4-carbonyl)pyridin-2-yl]amino]-6-oxopyridin-3-yl]phenyl]-3,4-dihydro-2,7-naphthyridin-1-one; and 6-tert-butyl-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(morpholine-4-carbonyl)pyridin-2-yl]amino]-6-oxopyridazin-3-yl]phenyl]-3,4-dihydro-2,7-naphthyridin-1-one. 6-tert-butyl-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(morpholine-4-carbonyl)pyridin-2-yl]amino]-6-oxopyridin-3-yl]phenyl]-3,4-dihydro-2,7-naphthyridin-1-one; and 6-tert-butyl-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(morpholine-4-carbonyl)pyridin-2-yl]amino]-6-oxopyridazin-3-yl]phenyl]-3,4-dihydro-2,7-naphthyridin-1-one.
A body composition analysis system (10, 10') having image scanning function, the body composition analysis system (10, 10') comprising an image capturing device; a body composition analyzer distanced from the image capturing device for a predetermined distance, the body composition analyzer having a stand platform, two handrails and a calculating unit, the stand platform being provided with two first electrode sets, the two handrails each having a telescopic rod and a handle, an end of each of the telescopic rods being pivotably attached to the stand platform, each of the handles being disposed at another end of each of the telescopic rods, each of the handles having a second electrode set, the calculating unit being electrically connected with the image capturing device, the calculating unit comprising a database, comprising data related to body shape stored therein, and a calculational logic, the calculating unit receiving resistance and reactance measured by the two first electrode sets and the two second electrode sets and receiving image data obtained by the image capturing device, and after comparing the image data obtained by the image capturing device with the data in the database, calculating by the calculational logic to obtain a body composition data; and a control panel electrically connected with the body composition analyzer, the image capturing device and the calculating unit for showing the body composition data. an image capturing device; a body composition analyzer distanced from the image capturing device for a predetermined distance, the body composition analyzer having a stand platform, two handrails and a calculating unit, the stand platform being provided with two first electrode sets, the two handrails each having a telescopic rod and a handle, an end of each of the telescopic rods being pivotably attached to the stand platform, each of the handles being disposed at another end of each of the telescopic rods, each of the handles having a second electrode set, the calculating unit being electrically connected with the image capturing device, the calculating unit comprising a database, comprising data related to body shape stored therein, and a calculational logic, the calculating unit receiving resistance and reactance measured by the two first electrode sets and the two second electrode sets and receiving image data obtained by the image capturing device, and after comparing the image data obtained by the image capturing device with the data in the database, calculating by the calculational logic to obtain a body composition data; and a control panel electrically connected with the body composition analyzer, the image capturing device and the calculating unit for showing the body composition data.
A pneumatic tire (1; 9; 10), comprising an outer apex which is located axially outward of a bead apex and which is formed from a rubber composition, the rubber composition having a thermal conductivity of 0.45 W/m·K or higher.
A controller comprising: a master clock (Cm); a controller clock (Ci, Cr); a master clock management unit configured to synchronize the master clock (Cm) with an external global clock and set a master time based on the master clock (Cm); a controller clock management unit configured to synchronize the controller clock (Ci, Cr) with the master clock (Cm) and perform time synchronization to synchronize a controller time based on the controller clock (Ci, Cr) with the master time, and to transmit controller time data indicating the synchronized controller time to at least one local device; characterized by further comprising a window setting unit configured to set a plurality of time windows corresponding to a plurality of clock cycles of a clock signal for the time synchronization; a determination unit configured to determine whether one clock cycle of the plurality of clock cycles has started within one time window of the plurality of time windows, the one time window corresponding to the one clock cycle; and an update control unit configured to suspend the time synchronization corresponding to the one clock cycle, in response to determining that the one clock cycle has not started within the one time window. a master clock (Cm); a controller clock (Ci, Cr); a master clock management unit configured to synchronize the master clock (Cm) with an external global clock and set a master time based on the master clock (Cm); a controller clock management unit configured to synchronize the controller clock (Ci, Cr) with the master clock (Cm) and perform time synchronization to synchronize a controller time based on the controller clock (Ci, Cr) with the master time, and to transmit controller time data indicating the synchronized controller time to at least one local device; characterized by further comprising a window setting unit configured to set a plurality of time windows corresponding to a plurality of clock cycles of a clock signal for the time synchronization; a determination unit configured to determine whether one clock cycle of the plurality of clock cycles has started within one time window of the plurality of time windows, the one time window corresponding to the one clock cycle; and an update control unit configured to suspend the time synchronization corresponding to the one clock cycle, in response to determining that the one clock cycle has not started within the one time window.
Process for partial coloring of plastic parts containing the steps of i) immersing a plastic part in a coloring bath, ii) optionally heating the coloring bath, iii) irradiating the plastic part from i) and optionally ii) with focused nonionizing electromagnetic radiation, wherein the partial coloring is effected substantially only at the sites irradiated in step iii); wherein the wavelength range of the focused nonionizing electromagnetic radiation is chosen such that the coloring bath has a light permeability of ≥ 10% to ≤ 99%, preferably of ≥ 30% to ≤ 95%, particularly preferably ≥ 40% to ≤ 93%, determined according to ISO 13468-2; wherein the plastic part comprises at least one additive which has an absorption maximum in the wavelength range of the employed focused nonionizing electromagnetic radiation or wherein the plastic part is coated with at least one additive in the form of a coating composition which has an absorption maximum in the wavelength range of the employed focused nonionizing electromagnetic radiation. i) immersing a plastic part in a coloring bath, ii) optionally heating the coloring bath, iii) irradiating the plastic part from i) and optionally ii) with focused nonionizing electromagnetic radiation, wherein the partial coloring is effected substantially only at the sites irradiated in step iii); wherein the wavelength range of the focused nonionizing electromagnetic radiation is chosen such that the coloring bath has a light permeability of ≥ 10% to ≤ 99%, preferably of ≥ 30% to ≤ 95%, particularly preferably ≥ 40% to ≤ 93%, determined according to ISO 13468-2; wherein the plastic part comprises at least one additive which has an absorption maximum in the wavelength range of the employed focused nonionizing electromagnetic radiation or wherein the plastic part is coated with at least one additive in the form of a coating composition which has an absorption maximum in the wavelength range of the employed focused nonionizing electromagnetic radiation.
Adapter for an irrigation and ventilation device for woody plants, the adapter comprising a pipe portion which has a connecting nozzle holder part having a flow regulator, that the flow regulator being replaceable, characterized in that the connecting nozzle holder part has an installation direction which, relative to the vertical pipe portion, is tangential to the pipe portion and inclined obliquely downward.
A high-strength thin steel sheet having a thickness of 1 to 4 mm and a tensile strength of 780 MPa or more orthogonal to the rolling direction according to JIS Z 2241, and comprising a chemical composition containing, in mass%, C: 0.05 % to 0.20 %, Si: 0.6 % to 1.5 %, Mn: 1.3 % to 3.0 %, P: 0.10 % or less, S: 0.030 % or less, Al: 0.10 % or less, N: 0.010 % or less, at least one selected from Ti: 0.01 % to 1.00 %, Nb: 0.01 % to 1.00 %, and V: 0.01 % to 1.00 %, optionally at least one selected from Mo: 0.005 % to 0.50 %, Ta: 0.005 % to 0.50 %, and W: 0.005 % to 0.50 %, optionally at least one selected from Cr: 0.01 % to 1.00 %, Ni: 0.01 % to 1.00 %, and Cu: 0.01 % to 1.00 %, optionally Sb: 0.005 % to 0.050 %, and optionally one or both selected from Ca: 0.0005 % to 0.0100 % and REM: 0.0005 % to 0.0100 %, the balance consisting of Fe and inevitable impurities, wherein the structure of the steel sheet is composed of ferrite whose area ratio is 50 % or more with respect to the entire structure and the balance, a conversion value C** of total carbon contents in Ti, Nb, V, Mo, Ta and W precipitates whose grain sizes are less than 20 nm, defined by the following formula, is 0.010 mass% to 0.100 mass%, Fe content in Fe precipitates is 0.03 mass% to 0.50 mass%, the Fe content in Fe precipitates being determined as described in the description, and an average grain size of ferrite grains whose grain sizes are top 5 % large in ferrite grain size distribution of rolling direction cross section is (4000/TS) 2 μm or less, the TS indicating tensile strength in unit of MPa, C * * = Ti / 48 + Nb / 93 + V / 51 + Mo / 96 + Ta / 181 + W / 184 × 12 where [Ti], [Nb],, [Mo], [Ta] and each indicate contents of Ti, Nb, V, Mo, Ta and W in Ti, Nb, V, Mo, Ta and W precipitates whose grain sizes are less than 20 nm, the contents being determined as described in the description.
Use of a polymer as an agglutination enhancer for immunoagglutination measurement method, the polymer having a monomer unit shown by the following general formula: wherein R 1 represents a hydrogen atom or a methyl group; R 2 and R 3 represent independently a methyl group or an ethyl group, respectively; X represents -NH- or an oxygen atom; n represents an integer of 1 to 6; and m represents an integer of 1 to 3.
A device to device, D2D, communication method, comprising: receiving, by a first terminal device, a control channel transmitted by a second terminal device on a first transmission time interval, TTI, wherein the control channel comprises a specific bit, and the specific bit is used to indicate a length of time domain used by the second terminal device for transmitting a data channel; sensing, by the first terminal device, the data channel transmitted by the second terminal device based on the first TTI if a value on the specific bit indicates that the length of time domain is equal to a length of the first TTI; and sensing, by the first terminal device, the data channel transmitted by the second terminal device based on a second TTI if the value on the specific bit indicates that the length of time domain is equal to a length of the second TTI, wherein the length of the second TTI is smaller than the length of the first TTI. receiving, by a first terminal device, a control channel transmitted by a second terminal device on a first transmission time interval, TTI, wherein the control channel comprises a specific bit, and the specific bit is used to indicate a length of time domain used by the second terminal device for transmitting a data channel; sensing, by the first terminal device, the data channel transmitted by the second terminal device based on the first TTI if a value on the specific bit indicates that the length of time domain is equal to a length of the first TTI; and sensing, by the first terminal device, the data channel transmitted by the second terminal device based on a second TTI if the value on the specific bit indicates that the length of time domain is equal to a length of the second TTI, wherein the length of the second TTI is smaller than the length of the first TTI.
A DNA molecule exhibiting the promoter activity of SEQ ID NO:31, comprising a polynucleotide sequence selected from: a) a sequence with at least 85 percent sequence identity to the full length of SEQ ID NO: 31; b) a sequence comprising SEQ ID NO: 31; and c) a fragment comprising at least 500 contiguous nucleotides of SEQ ID NO: 31 and having the promoter activity of SEQ ID NO: 31; wherein said DNA molecule is operably linked to a transcribable polynucleotide molecule which is heterologous with respect to said DNA molecule. a) a sequence with at least 85 percent sequence identity to the full length of SEQ ID NO: 31; b) a sequence comprising SEQ ID NO: 31; and c) a fragment comprising at least 500 contiguous nucleotides of SEQ ID NO: 31 and having the promoter activity of SEQ ID NO: 31;
A method for the harvesting and removing at least part of micro-algae from water, wherein the micro-algae are cultivated in commercial photo-bioreactor systems, the method being characterized in that it includes: contacting carbonaceous fines with the water under conditions that permit adsorption of micro-algae onto particles of carbonaceous fines and in which the carbonaceous fines are loaded with micro-algae adsorbed thereon to an amount of from 1% to 25% micro-algae by weight of the carbonaceous fines; separating the carbonaceous fines together with the adsorbed micro-algae thereon from the water; and subjecting the carbonaceous fines together with the adsorbed micro-algae thereon to an agglomeration process for the production of agglomerates of the resultant admixture as part of a beneficiation of carbonaceous fines; and wherein the micro-algae serve as a binder. contacting carbonaceous fines with the water under conditions that permit adsorption of micro-algae onto particles of carbonaceous fines and in which the carbonaceous fines are loaded with micro-algae adsorbed thereon to an amount of from 1% to 25% micro-algae by weight of the carbonaceous fines; separating the carbonaceous fines together with the adsorbed micro-algae thereon from the water; and subjecting the carbonaceous fines together with the adsorbed micro-algae thereon to an agglomeration process for the production of agglomerates of the resultant admixture as part of a beneficiation of carbonaceous fines; and wherein the micro-algae serve as a binder.
A method of adaptively processing an input signal, the method comprising: passing the input signal through an adaptive time domain filter to produce an output signal; taking at least one of the input signal and the output signal as an analysis signal; transforming the analysis signal into a frequency domain to produce a transformed analysis signal; analysing the transformed analysis signal to produce a plurality of logarithmically expressed desired gains each corresponding to a respective frequency domain sub-band; synthesising a minimum phase time domain filter characteristic having a magnitude response which approximates a gain profile of the plurality of desired gains, the synthesising comprising: obtaining a cepstrum as an inverse discrete Fourier transform of the logarithmically expressed desired gains; adjusting the cepstrum to generate an adjusted cepstrum which is causal; and applying a discrete Fourier transform to the adjusted causal cepstrum to produce a minimum phase complex frequency response comprising logarithmically expressed complex gains; and updating the adaptive filter with the synthesised filter characteristic. passing the input signal through an adaptive time domain filter to produce an output signal; taking at least one of the input signal and the output signal as an analysis signal; transforming the analysis signal into a frequency domain to produce a transformed analysis signal; analysing the transformed analysis signal to produce a plurality of logarithmically expressed desired gains each corresponding to a respective frequency domain sub-band; synthesising a minimum phase time domain filter characteristic having a magnitude response which approximates a gain profile of the plurality of desired gains, the synthesising comprising: obtaining a cepstrum as an inverse discrete Fourier transform of the logarithmically expressed desired gains; adjusting the cepstrum to generate an adjusted cepstrum which is causal; and applying a discrete Fourier transform to the adjusted causal cepstrum to produce a minimum phase complex frequency response comprising logarithmically expressed complex gains; and updating the adaptive filter with the synthesised filter characteristic. obtaining a cepstrum as an inverse discrete Fourier transform of the logarithmically expressed desired gains; adjusting the cepstrum to generate an adjusted cepstrum which is causal; and applying a discrete Fourier transform to the adjusted causal cepstrum to produce a minimum phase complex frequency response comprising logarithmically expressed complex gains; and updating the adaptive filter with the synthesised filter characteristic.
Method for chromatic confocal multipoint measurement with colour splitting in the propagation direction of the illumination light based on a point-wise chromatic confocal distance measurement, characterized in that the chromatically coded measurement values of a plurality of measurement points, which are laterally spaced apart perpendicularly to the propagation direction and in which a reference wavelength λ 0 is focused in each case at different axial distances from a sensor, are transmitted to a detector unit with a spectral multiplexing method, wherein each measurement point is assigned a spectral partial band of the entire spectral bandwidth of the illumination light and a respectively different focal length, and wherein, in the spectral multiplexing method, the spectral partial bands that are assigned to the plurality of measurement points are transmitted simultaneously to the detection unit via an individual broadband optical channel.
Composition comprising a first and a second isolated protein, wherein the first isolated protein is a Bm86 protein or a homolog thereof, comprising an amino acid sequence having an amino acid sequence identity of at least 71 % with the amino acid sequence according to SEQ ID NO: 1, and wherein the second isolated protein is a Subolesin protein or a homolog thereof, comprising an amino acid sequence having an amino acid sequence identity of at least 96 % with the amino acid sequence according to SEQ ID NO: 2, and wherein the two proteins are physically separated from each other.
Nail-tight sealing membrane, in particular under-roof membrane or façade membrane, comprising, in this order, a first nonwoven layer, a membrane layer and a second nonwoven layer, the first nonwoven layer comprising polypropylene fibers and the second nonwoven layer comprising polypropylene fibers and the membrane layer being formed on the basis of a thermoplastic elastomer, the second nonwoven layer having a weight per unit area of between 40 g/m 2 and 200 g/m 2, and the first nonwoven layer has a weight per unit area of between 60 g/m 2 and 200 g/m 2, characterized in that the sealing membrane comprises the first nonwoven layer, the membrane layer and the second nonwoven layer, the first nonwoven layer optionally being bonded to the membrane layer via an adhesive layer and/or the membrane layer optionally being bonded to the second nonwoven layer via an adhesive layer.
A storage cell unit for a motor vehicle with an electric drive, having a housing in which storage cells are arranged, characterized in that the housing has an energy absorption region (7, 71, 72, 73, 74) which is formed such that it is deformable for the purpose of absorbing energy in the event of a collision, wherein the energy absorption region (7, 71, 72, 73, 74) is formed by a wall element of the housing, wherein the housing further has a storage cell protection region in which the storage cells are arranged and which is formed such that it is not deformable in the event of the collision.