mhurhangee/ep-ind-claims huggingface dataset:
An effective amount of an immunotoxin for use in treating or preventing head and neck squamous cell carcinoma by administering it directly to the cancer site intratumorally or peritumorally, and wherein said immunotoxin comprises: (a) an antibody or an antibody fragment that binds to Ep-CAM on the cancer cell attached to; (b) a toxin that is cytotoxic to the cancer cell. (a) an antibody or an antibody fragment that binds to Ep-CAM on the cancer cell attached to; (b) a toxin that is cytotoxic to the cancer cell.
A lidocaine-containing hydrogel patch comprising: a support layer; and an adhesive layer stacked on a surface of the support layer, wherein the adhesive layer comprises at least one selected from the group consisting of lidocaine and pharmaceutically acceptable salts thereof, a total content of the lidocaine and the pharmaceutically acceptable salts thereof is 3 to 8% by mass relative to an entire mass of the adhesive layer, the adhesive layer further comprises oleic acid in an amount of 0.3 to 1% by mass relative to the entire mass of the adhesive layer, the adhesive layer further comprises an acid-treated gelatin, and a pH of the adhesive layer is 6.8 to 7.4. a support layer; and an adhesive layer stacked on a surface of the support layer, wherein the adhesive layer comprises at least one selected from the group consisting of lidocaine and pharmaceutically acceptable salts thereof, a total content of the lidocaine and the pharmaceutically acceptable salts thereof is 3 to 8% by mass relative to an entire mass of the adhesive layer, the adhesive layer further comprises oleic acid in an amount of 0.3 to 1% by mass relative to the entire mass of the adhesive layer, the adhesive layer further comprises an acid-treated gelatin, and a pH of the adhesive layer is 6.8 to 7.4.
A method for manufacturing a vehicle side airbag module having a side airbag inflated and deployed from a seat back to a vehicle front side through a side of a seat by inflator gas ejected from an inflator stored inside, the side airbag having an inflator storing region provided on a rear side in a vehicle front-back direction to store the inflator, the method comprising the steps of: folding an upper region of the side airbag above a folding line on a lower region thereof under the folding line along the folding line, and setting on the side airbag a folding region for folding the side airbag into a cone shape having a tapered upper part and a widened lower part, the folding line being set across the side airbag from a vehicle rear side to a vehicle front side; characterized by folding the folding region toward the inflator storing region with respect to at least one folding center set in a region vacating the upper region as a reference and forming a folded part. folding an upper region of the side airbag above a folding line on a lower region thereof under the folding line along the folding line, and setting on the side airbag a folding region for folding the side airbag into a cone shape having a tapered upper part and a widened lower part, the folding line being set across the side airbag from a vehicle rear side to a vehicle front side; characterized by folding the folding region toward the inflator storing region with respect to at least one folding center set in a region vacating the upper region as a reference and forming a folded part.
A semiconductor device, comprising: a substrate panel having interconnects; a first die (921, 922) and a second die (952, 953) coupled through packaging connections to the first die; the first die comprising a first surface and a second surface opposite the first surface, the first surface being supported by the substrate, the first die further comprising through silicon vias extending from the first surface of the first die to the second surface of the first die; a packaging connection between the substrate panel and the first die, the packaging connection coupled to the through silicon vias to facilitate communication between the substrate and the first die; a first molding compound between the substrate panel and the first die, the first molding compound partially surrounding the first die and arranged to fix the first die (921, 922) onto the substrate panel, a sidewall of the first molding compound being flush with a sidewall of the substrate panel; an isolation layer deposited on the second surface of the first die and supported in part by the first molding compound; wherein the isolation layer and back end of line layers are co-planar with the substrate panel; metal connections deposited in etched regions of said isolation layer; a second molding compound partially surrounding the second die to fix it; wherein a sidewall of the second molding compound is flush with the sidewall of the first molding compound and a sidewall of the isolation layer, and a surface of the second molding compound is adjacent with a second surface of the isolation layer. a substrate panel having interconnects; a first die (921, 922) and a second die (952, 953) coupled through packaging connections to the first die; the first die comprising a first surface and a second surface opposite the first surface, the first surface being supported by the substrate, the first die further comprising through silicon vias extending from the first surface of the first die to the second surface of the first die; a packaging connection between the substrate panel and the first die, the packaging connection coupled to the through silicon vias to facilitate communication between the substrate and the first die; a first molding compound between the substrate panel and the first die, the first molding compound partially surrounding the first die and arranged to fix the first die (921, 922) onto the substrate panel, a sidewall of the first molding compound being flush with a sidewall of the substrate panel; an isolation layer deposited on the second surface of the first die and supported in part by the first molding compound; wherein the isolation layer and back end of line layers are co-planar with the substrate panel; metal connections deposited in etched regions of said isolation layer; a second molding compound partially surrounding the second die to fix it; wherein a sidewall of the second molding compound is flush with the sidewall of the first molding compound and a sidewall of the isolation layer, and a surface of the second molding compound is adjacent with a second surface of the isolation layer.
Guide and fastening device for plant support wires, in particular for rows of grapevines, the device comprising at least one pair of vertical upright elements, fastened to a head pole and provided with longitudinal guides within which are made to slide fastening elements for the lateral vegetation containment wires, characterized in that to each pair of uprights for the lateral containment wires is associated a further vertical upright provided with a guide wherein is made to slide a fastening element for at least one training wire.
A vascular graft, comprising: a tubular conduit comprising a tubular wall, the tubular wall defining a lumen for the passage of blood therethrough; and wherein the tubular wall comprises an acellular tissue matrix having a basement membrane, the basement membrane forming a luminal surface of the tubular wall wherein a first longitudinal edge of the acellular tissue matrix is attached to a second longitudinal edge of the acellular tissue matrix with an adhesive to form a fluid-tight seam extending along the length of the graft, wherein the attachment of the first and the second longitudinal edges creates a longitudinal ridge protruding from an abluminal surface of the tubular wall. a tubular conduit comprising a tubular wall, the tubular wall defining a lumen for the passage of blood therethrough; and wherein the tubular wall comprises an acellular tissue matrix having a basement membrane, the basement membrane forming a luminal surface of the tubular wall wherein a first longitudinal edge of the acellular tissue matrix is attached to a second longitudinal edge of the acellular tissue matrix with an adhesive to form a fluid-tight seam extending along the length of the graft, wherein the attachment of the first and the second longitudinal edges creates a longitudinal ridge protruding from an abluminal surface of the tubular wall.
A method to reduce crediting errors due to spillover in a dwelling or across adjacent dwellings, comprising: determining, by a processor, if first media monitoring data provided from a first meter identifies a same media as second media monitoring data provided from a second meter, the first meter and the second meter to monitor presented media at respective different locations of the dwelling or the adjacent dwellings; if the first media monitoring data identifies the same media as the second media monitoring data, detecting, by the processor, if spillover occurred by determining the absolute value of the difference between a first timestamp associated with the first media monitoring data and a second timestamp associated with the second media monitoring data is not less than a threshold; if spillover occurred, determining, by the processor, which of the first media monitoring data or the second media monitoring data to credit with a media exposure; and crediting the first media monitoring data or the second media monitoring data with the media exposure corresponding to the earliest associated timestamp. determining, by a processor, if first media monitoring data provided from a first meter identifies a same media as second media monitoring data provided from a second meter, the first meter and the second meter to monitor presented media at respective different locations of the dwelling or the adjacent dwellings; if the first media monitoring data identifies the same media as the second media monitoring data, detecting, by the processor, if spillover occurred by determining the absolute value of the difference between a first timestamp associated with the first media monitoring data and a second timestamp associated with the second media monitoring data is not less than a threshold; if spillover occurred, determining, by the processor, which of the first media monitoring data or the second media monitoring data to credit with a media exposure; and crediting the first media monitoring data or the second media monitoring data with the media exposure corresponding to the earliest associated timestamp.
A light grid having a plurality of first light transmitters which are arranged with an equidistant mutual grid distance and a plurality of first light receivers which are arranged opposite the respective first light transmitters with the equidistant grid distance, forming direct monitoring beams between one another, wherein the first light transmitters and first light receivers additionally have an aperture angle where also crossing monitoring beams with neighbors of mutually assigned first light transmitters and first light receivers are formed, characterized in that at least one additional light transmitter is arranged in an intermediate space between two first light transmitters and/or at least one additional light receiver is arranged in an intermediate space between two first light receivers, wherein additional light transmitters and/or light receivers are only arranged in a part of the intermediate spaces, and in that any position in the middle of the first light transmitters and the first light receivers which is free from monitoring beams (18a-b) of the first light transmitters and first light receivers is passed by at least one additional monitoring beam generated by the additional light transmitters and/or additional light receivers, so that the resolution of the light grid is increased with only a few additional components.
A radiation therapy system, comprising: a magnetic resonance imaging system, the MRI system including first and second main MRI magnets separated by an MRI magnet gap, wherein the first and second main MRI magnets are configured to operate together to produce a magnetic field, at least a portion of the magnetic field extending along a first longitudinal axis that extends through an isocenter of the MRI system; a gantry positioned in the MRI magnet gap, the gantry being rotatable about the first longitudinal axis; a linear particle accelerator, linac, supported by the gantry at a first fixed radial distance from the isocenter, the linac being aligned along a second axis (p) and being configured to rotate with the gantry and to direct a radiation beam towards the isocenter; characterised in that the radiation therapy system further comprises: a magnetic shield supported by the gantry at a second fixed radial distance from the isocenter, wherein the magnetic shield includes at least a first shell having a first magnetic permeability and a secondary shielding element comprising a second shell, separate from the first shell, having a second magnetic permeability, wherein the second magnetic permeability is higher than the first magnetic permeability, wherein the second shell has a lower saturation flux density than the first shell, wherein the second shell is positioned inside of the first shell, wherein both shells are placed around the linac. a magnetic resonance imaging system, the MRI system including first and second main MRI magnets separated by an MRI magnet gap, wherein the first and second main MRI magnets are configured to operate together to produce a magnetic field, at least a portion of the magnetic field extending along a first longitudinal axis that extends through an isocenter of the MRI system; a gantry positioned in the MRI magnet gap, the gantry being rotatable about the first longitudinal axis; a linear particle accelerator, linac, supported by the gantry at a first fixed radial distance from the isocenter, the linac being aligned along a second axis (p) and being configured to rotate with the gantry and to direct a radiation beam towards the isocenter; characterised in that the radiation therapy system further comprises: a magnetic shield supported by the gantry at a second fixed radial distance from the isocenter, wherein the magnetic shield includes at least a first shell having a first magnetic permeability and a secondary shielding element comprising a second shell, separate from the first shell, having a second magnetic permeability, wherein the second magnetic permeability is higher than the first magnetic permeability, wherein the second shell has a lower saturation flux density than the first shell, wherein the second shell is positioned inside of the first shell, wherein both shells are placed around the linac.
Cable-pulling actuation system for a parking brake comprising - a body that houses motor means, - a tie rod, suitable to actuate along an actuation direction (X-X), in correspondence of a first end, an actuating member of a drum brake and/or a parking brake, - transmission means that operatively connect the motor means to a second end of the tie rod, - wherein the second end of the tie rod is integral in translation with a first screw, having a first thread with a first pitch, - wherein said first screw is engaged, through the first thread, in a second screw, - the second screw comprises a second thread with a second pitch, through which is in turn engaged in a nut screw integral with the body, the second thread being opposite to the first thread, - the second screw being actuated in rotation by said transmission means, characterised in that the second screw is engaged with a second prismatic coupling to an output gear of the transmission means, in order to roto-translate with respect to the actuation direction (X-X), while maintaining the mechanical connection with the transmission means. - a body that houses motor means, - a tie rod, suitable to actuate along an actuation direction (X-X), in correspondence of a first end, an actuating member of a drum brake and/or a parking brake, - transmission means that operatively connect the motor means to a second end of the tie rod, - wherein the second end of the tie rod is integral in translation with a first screw, having a first thread with a first pitch, - wherein said first screw is engaged, through the first thread, in a second screw, - the second screw comprises a second thread with a second pitch, through which is in turn engaged in a nut screw integral with the body, the second thread being opposite to the first thread, - the second screw being actuated in rotation by said transmission means,
A refrigerating cycle apparatus in which a refrigerating cycle is connected circularly through a compressor, a condenser, a flow controller, and an evaporator (5, 7), respectively, wherein the flow controller comprising a multi-directional valve connected in parallel with a throttle device having at least one porous permeable member (20, 25) communicating in a refrigerant flow direction in a flow path is disposed in a divided intermediate flow path of the evaporator (5, 7), and a gas/liquid two-phase refrigerant is caused to pass through the throttle section, characterized in that the throttle device comprises an orifice, wherein the porous permeable member (20, 25) is disposed at least at one of the upstream side and the downstream side of the orifice in the refrigerant flow direction, in that a space (22, 24) is defined between the orifice and the porous permeable member (20, 25), and in that bypass flow paths (21, 26) are formed through foamed metal as the porous permeable members (20, 25) at positions where the bypass flow paths (21, 26) are not superimposed on the orifice, wherein through hole diameters of the bypass flow paths (21, 26) are equal to or larger than the minimum diameters of 100 μm of the vent holes of the porous permeable members (20, 25).
Flat steel product for a subsequent austenitizing annealing treatment in a furnace at a furnace temperature in the range of 880 to 950°C, comprising an aluminum-based coating, the coating comprising an aluminum-based coat which is applied in a hot-dipping process and has 1.8 to 15 mass percent silicon, advantageously 5 to 13 mass percent silicon, even more advantageously 8 to 11 mass percent silicon, characterized in that the coat - for determining an absorption degree of the surface of the coating for thermal radiation, which is relative to the aforementioned range of the furnace temperature during the austenitizing annealing treatment, in a range of from 0.35 to 0.95, in particular from 0.40 to 0.80, advantageously from 0.45 to 0.70 - starting from the surface within the first 0.05 μm, has an average silicon content between 25 and 70 mass percent.
An apparatus for laying cables and/or lines, with at least one rotatable milling wheel, which is designed to cut a groove into an asphalted and/or an otherwise at least approximately air-tightly and/or water-tightly sealed ground layer, wherein the apparatus comprises a laying device with a feeding device for the cables and/or lines to be laid, the laying device being arranged downstream from the milling wheel in a direction of movement of the apparatus, and/or being couplable with the milling wheel and/or adjustable, and being designed for laying at least one cable and/or at least one line, the laying device being adjustable in height relative to the ground surface via at least one actuator, and being characterised in that the laying device is adjustable in inclination relative to a frame accommodating the milling wheel via at least one actuator, and in that the laying device is designed for material compaction with side shoulders, at least in some sections, that are inclined toward one another in a V-shaped cross section, wherein loosened material can be pushed and recompacted into cavities and/or uncompacted areas formed at the sides of the milled groove by means of the laying device during the forward movement in the direction of movement, and in that the laying device is designed to be exchangeable for a clearing device.
An infusion dosage form comprising i. an aqueous solution of morphine or its pharmaceutically acceptable salt as a sole active ingredient in a concentration ranging from about 0.1 mg/ml to about 10.0 mg/ml, filled in containers in volumes ranging from about 50 ml to about 250 ml, and having dissolved oxygen content of less than 2 ppm, ii. the container being surrounded by an outer covering, and iii. an inert gas or vacuum in the space between the container and outer covering, wherein the infusion container surrounded by an outer covering and having an inert gas in the space between the container and the outer covering is sterilized by autoclaving, wherein the infusion dosage form is stable upon autoclaving, wherein the space between the container and outer covering does not have an oxygen scavenger pouch before or during autoclaving, further wherein the container is a flexible infusion container. i. an aqueous solution of morphine or its pharmaceutically acceptable salt as a sole active ingredient in a concentration ranging from about 0.1 mg/ml to about 10.0 mg/ml, filled in containers in volumes ranging from about 50 ml to about 250 ml, and having dissolved oxygen content of less than 2 ppm, ii. the container being surrounded by an outer covering, and iii. an inert gas or vacuum in the space between the container and outer covering, wherein the infusion container surrounded by an outer covering and having an inert gas in the space between the container and the outer covering is sterilized by autoclaving, wherein the infusion dosage form is stable upon autoclaving, wherein the space between the container and outer covering does not have an oxygen scavenger pouch before or during autoclaving, further wherein the container is a flexible infusion container.
A method for simultaneously measuring a respiration rate and a heart rate using dual cameras (120, 160) of a smartphone, the method comprising: collecting, at a first step, a PPG signal of a human with a first camera of a smartphone and visual data on chest and abdomen movements of the human with a second camera of the smartphone; converting, at a second step, the visual data to an RGBA signal; applying, at a third step, a bandpass filter such that a frequency only within a range in the RGBA signal passes; removing, at a fourth step, first and last predetermined time-portions of the RGBA signal to which the band-pass filter is applied at the third step; selecting, at a fifth step, a color channel having a highest standard deviation from the RGBA signal where the predetermined portions are removed at the fourth step; applying, at a sixth step, a spline filter to the color channel selected at the fifth step; computing, at a seventh step, power spectrum density using the result of the sixth step; and computing, at an eighth step, a heart rate and a respiration rate using the result of the seventh step. collecting, at a first step, a PPG signal of a human with a first camera of a smartphone and visual data on chest and abdomen movements of the human with a second camera of the smartphone; converting, at a second step, the visual data to an RGBA signal; applying, at a third step, a bandpass filter such that a frequency only within a range in the RGBA signal passes; removing, at a fourth step, first and last predetermined time-portions of the RGBA signal to which the band-pass filter is applied at the third step; selecting, at a fifth step, a color channel having a highest standard deviation from the RGBA signal where the predetermined portions are removed at the fourth step; applying, at a sixth step, a spline filter to the color channel selected at the fifth step; computing, at a seventh step, power spectrum density using the result of the sixth step; and computing, at an eighth step, a heart rate and a respiration rate using the result of the seventh step.