A medication compliance package for use in dispensing solid medications to patients comprising: a carrier and a blister insert sheet to be carried within the carrier; the blister insert sheet comprising a plurality of raised pockets arranged in rows and columns, each of which can be compressed by a digit of a hand of a user to expel the solid medications contained within the pocket through an open mouth of the pocket; the carrier comprising a generally rectangular front panel with a front face and a rear face and a generally rectangular rear panel with a front face and a rear face the front panel and the rear panel being hingedly connected together along one corresponding mutual side edge (16, 17) thereof so that the front and rear panels can be moved between a closed position where the front and rear panels are parallel and overlie for closing a rear face of the front panel over a front face of the rear panel and an open position in which the front panel is moved away from overlaying the rear panel; the rear panel having a plurality of apertures arranged in rows and columns matching the rows and columns of the blister insert sheet and formed through the rear panel such that the blister insert sheet can be arranged with the raised pockets thereof projecting forwardly of the front face of the rear panel from the apertures of the rear panel; a frangible layer covering the open mouths of the pockets at the rear face of the rear panel; the front panel having an opening at or adjacent the mutual side (16, 17) edge with the rear panel; the opening being shaped and arranged to allow fingers of the hand of the user to extend through the opening, with the front and rear panels (11, 12) in the open position, from the rear face of the front panel to reach around the mutual side edge to the rear face of the rear panel. a carrier and a blister insert sheet to be carried within the carrier; the blister insert sheet comprising a plurality of raised pockets arranged in rows and columns, each of which can be compressed by a digit of a hand of a user to expel the solid medications contained within the pocket through an open mouth of the pocket; the carrier comprising a generally rectangular front panel with a front face and a rear face and a generally rectangular rear panel with a front face and a rear face the front panel and the rear panel being hingedly connected together along one corresponding mutual side edge (16, 17) thereof so that the front and rear panels can be moved between a closed position where the front and rear panels are parallel and overlie for closing a rear face of the front panel over a front face of the rear panel and an open position in which the front panel is moved away from overlaying the rear panel; the rear panel having a plurality of apertures arranged in rows and columns matching the rows and columns of the blister insert sheet and formed through the rear panel such that the blister insert sheet can be arranged with the raised pockets thereof projecting forwardly of the front face of the rear panel from the apertures of the rear panel; a frangible layer covering the open mouths of the pockets at the rear face of the rear panel; the front panel having an opening at or adjacent the mutual side (16, 17) edge with the rear panel; the opening being shaped and arranged to allow fingers of the hand of the user to extend through the opening, with the front and rear panels (11, 12) in the open position, from the rear face of the front panel to reach around the mutual side edge to the rear face of the rear panel.