A compound of Formula: or a salt, racemate, isomer, diastereoisomer, enantiomer, hydrate, solvate or N-oxide thereof wherein W is a substituted C 6-10 -membered monocyclic or fused bicyclic aryl group or an optionally substituted 5-6-membered monocyclic heteroaryl or a 9-membered fused bicyclic heteroaryl group; R 1 and R 2 are each independently selected from halo or H; R 3 is selected from the group consisting of C t alkyl-R 4, C 2-6 alkenyl, C 2-6 alkynyl, C 3-7 cycloalkyl, C 6 aryl, and 5-6 membered heterocyclyl wherein each alkyl, alkenyl, alkynyl, cycloalkyl, aryl or heterocyclyl may be optionally substituted with one or more R 4 or R 5 groups; t is an integer selected from 0, 1, 2 and 3; R 4 is selected from the group consisting of C 2-6 alkenyl, C 2-6 alkynyl, C 6-10 aryl, C 1-6 alkylaryl, 4-10 membered heterocyclyl, C 1-6 alkylheterocyclyl, OR 6, (C=O)R 6, O(C=O)R 6, C(=O)OR 6, N(R 6) 2, NR 6 C(=O)R 5, C(=O)N(R 6) 2, NR 6 C(=O)OR 5, OC(=O)N(R 6) 2, C(=O)NH-NHC(=O)R 5, NHC(=O)NHC 1-6 alkyl, NHS x R 5, S x R 5, OS x R 5, OP(=O)(OR 6) 2 and P(=O)(OR 6) 2 wherein each C 2-6 alkenyl, C 2-6 alkynyl, C 6-10 aryl, C 1-6 alkylaryl, 4-10 membered heterocyclyl and C 1-6 alkylheterocyclyl independently may be further optionally substituted with one or more optional substituents independently selected from the group consisting of C 1-3 alkyl, C 2-3 alkenyl, C 1-3 alkoxyl, OR 7, oxo, (C=O)R 7, O(C=O)R 7, C(=O)OR 7, N(R 7) 2, NR 7 C(=O)R 7, C(=O)N(R 7) 2, NR 7 C(=O)OR 7, OC(=O)N(R 7) 2, C(=O)NH-NHC(=O)R 7, S x R 7, OS x R 7, OP(=O)(OR 7) 2 and P(=O)(OR 7) 2 wherein each R 7 is independently selected from H, C 1-3 alkyl and C 2-3 alkenyl; each R 5 is optionally substituted and is selected from C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 6-10 aryl, C 1-6 alkylaryl, 4-10 membered heterocyclyl and C 1-6 alkylheterocyclyl; each R 6 is independently selected from H or optionally substituted C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 6-10 aryl, C 1-6 alkylaryl, 4-10 membered heterocyclyl and C 1-6 alkylheterocyclyl; wherein each R 5 and R 6 independently may be further optionally substituted with one or more optional substituents independently selected from the group consisting of C 1-3 alkyl, C 2-3 alkenyl, C 1-3 alkoxyl, OR 7, oxo, (C=O)R 7, O(C=O)R 7, C(=O)OR 7, N(R 7) 2, NR 7 C(=O)R 7, C(=O)N(R 7) 2, NR 7 C(=O)OR 7, OC(=O)N(R 7) 2, C(=O)NH-NHC(=O)R 7, S x R 7, OS x R 7, OP(=O)(OR 7) 2 and P(=O)(OR 7) 2 wherein each R 7 is independently selected from H, C 1-3 alkyl and C 2-3 alkenyl; and x is 0 or an integer from 1 to 2. W is a substituted C 6-10 -membered monocyclic or fused bicyclic aryl group or an optionally substituted 5-6-membered monocyclic heteroaryl or a 9-membered fused bicyclic heteroaryl group; R 1 and R 2 are each independently selected from halo or H; R 3 is selected from the group consisting of C t alkyl-R 4, C 2-6 alkenyl, C 2-6 alkynyl, C 3-7 cycloalkyl, C 6 aryl, and 5-6 membered heterocyclyl wherein each alkyl, alkenyl, alkynyl, cycloalkyl, aryl or heterocyclyl may be optionally substituted with one or more R 4 or R 5 groups; t is an integer selected from 0, 1, 2 and 3; R 4 is selected from the group consisting of C 2-6 alkenyl, C 2-6 alkynyl, C 6-10 aryl, C 1-6 alkylaryl, 4-10 membered heterocyclyl, C 1-6 alkylheterocyclyl, OR 6, (C=O)R 6, O(C=O)R 6, C(=O)OR 6, N(R 6) 2, NR 6 C(=O)R 5, C(=O)N(R 6) 2, NR 6 C(=O)OR 5, OC(=O)N(R 6) 2, C(=O)NH-NHC(=O)R 5, NHC(=O)NHC 1-6 alkyl, NHS x R 5, S x R 5, OS x R 5, OP(=O)(OR 6) 2 and P(=O)(OR 6) 2 wherein each C 2-6 alkenyl, C 2-6 alkynyl, C 6-10 aryl, C 1-6 alkylaryl, 4-10 membered heterocyclyl and C 1-6 alkylheterocyclyl independently may be further optionally substituted with one or more optional substituents independently selected from the group consisting of C 1-3 alkyl, C 2-3 alkenyl, C 1-3 alkoxyl, OR 7, oxo, (C=O)R 7, O(C=O)R 7, C(=O)OR 7, N(R 7) 2, NR 7 C(=O)R 7, C(=O)N(R 7) 2, NR 7 C(=O)OR 7, OC(=O)N(R 7) 2, C(=O)NH-NHC(=O)R 7, S x R 7, OS x R 7, OP(=O)(OR 7) 2 and P(=O)(OR 7) 2 wherein each R 7 is independently selected from H, C 1-3 alkyl and C 2-3 alkenyl; each R 5 is optionally substituted and is selected from C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 6-10 aryl, C 1-6 alkylaryl, 4-10 membered heterocyclyl and C 1-6 alkylheterocyclyl; each R 6 is independently selected from H or optionally substituted C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 6-10 aryl, C 1-6 alkylaryl, 4-10 membered heterocyclyl and C 1-6 alkylheterocyclyl; wherein each R 5 and R 6 independently may be further optionally substituted with one or more optional substituents independently selected from the group consisting of C 1-3 alkyl, C 2-3 alkenyl, C 1-3 alkoxyl, OR 7, oxo, (C=O)R 7, O(C=O)R 7, C(=O)OR 7, N(R 7) 2, NR 7 C(=O)R 7, C(=O)N(R 7) 2, NR 7 C(=O)OR 7, OC(=O)N(R 7) 2, C(=O)NH-NHC(=O)R 7, S x R 7, OS x R 7, OP(=O)(OR 7) 2 and P(=O)(OR 7) 2 wherein each R 7 is independently selected from H, C 1-3 alkyl and C 2-3 alkenyl; and x is 0 or an integer from 1 to 2.