A method of configuring a timing advance group for a secondary cell, in a base station, the method comprising the steps of: II1. triggering a random access procedure of a user equipment over the secondary cell; II2. obtaining a timing advance value of the user equipment over the secondary cell according to a result of the random access procedure of the user equipment over the secondary cell; and II3. determining a final timing advance group to which the secondary cell belongs according to the timing advance value, wherein, after the step II3, the method further comprises the step of: II4. providing the user equipment with an identifier of the final timing advance group, wherein before the step II1, the method further comprises the steps of: I. transmitting an initial timing advance group identifier to the secondary cell of the user equipment via a radio link control message or a media access control protocol data unit; and II. determining whether the timing advance group identifier is valid for the secondary cell; and If it is invalid for the secondary cell, then performing the step II1 and the step II2; and the step II3 further comprises: comparing obtained timing advance value with timing advance values pre-stored in the base station; and II31. taking a timing advance group corresponding to the pre-stored timing advance value as the final timing advance group of the secondary cell, when a difference between the obtained timing advance value and any one of timing advance values pre_stored in the base station is within a predetermined range; or II32. taking a timing advance group corresponding to the obtained timing advance value as the final timing advance group of the secondary cell, when a difference between the obtained timing advance value and any one of the timing advance values pre-stored in the base station exceeds the predetermined range. II1. triggering a random access procedure of a user equipment over the secondary cell; II2. obtaining a timing advance value of the user equipment over the secondary cell according to a result of the random access procedure of the user equipment over the secondary cell; and II3. determining a final timing advance group to which the secondary cell belongs according to the timing advance value, wherein, after the step II3, the method further comprises the step of: II4. providing the user equipment with an identifier of the final timing advance group, wherein before the step II1, the method further comprises the steps of: I. transmitting an initial timing advance group identifier to the secondary cell of the user equipment via a radio link control message or a media access control protocol data unit; and II. determining whether the timing advance group identifier is valid for the secondary cell; and If it is invalid for the secondary cell, then performing the step II1 and the step II2; and the step II3 further comprises: comparing obtained timing advance value with timing advance values pre-stored in the base station; and I. transmitting an initial timing advance group identifier to the secondary cell of the user equipment via a radio link control message or a media access control protocol data unit; and II. determining whether the timing advance group identifier is valid for the secondary cell; and If it is invalid for the secondary cell, then performing the step II1 and the step II2; and the step II3 further comprises: comparing obtained timing advance value with timing advance values pre-stored in the base station; and II31. taking a timing advance group corresponding to the pre-stored timing advance value as the final timing advance group of the secondary cell, when a difference between the obtained timing advance value and any one of timing advance values pre_stored in the base station is within a predetermined range; or II32. taking a timing advance group corresponding to the obtained timing advance value as the final timing advance group of the secondary cell, when a difference between the obtained timing advance value and any one of the timing advance values pre-stored in the base station exceeds the predetermined range.