mhurhangee/ep-ind-claims huggingface dataset:
A bifunctional oligonucleotide for use in a Forward Inner Primer and Reverse Inner Primer loop-mediated isothermal nucleic acid amplification reaction (LAMP) for a specific sequence of a target gene, wherein the oligonucleotide is one of the oligonucleotides set forth in SEQ ID NOS 5 - 8 and 15 - 16, wherein the oligonucleotide has two target gene sites, and a reporter dye is positioned at a 5' direction of the two target gene sites and a quencher is positioned at a 3' direction of the two target gene sites, and a base of the sequence in which the corresponding reporter dye or quencher is located is modified from thymine to amino-C6 (or C2)-deoxythymine, or from adenine, thymine, guanine, cytosine or uridine to amino-C6-deoxyribose; such that all or a part of the sequences of said oligonucleotide form a double-strand at a certain temperature or lower, the oligonucleotide having one to four bubble structures that are formed between the two target gene sites; and wherein there is a 21~33 mer interval between the reporter dye and the quencher. wherein the oligonucleotide is one of the oligonucleotides set forth in SEQ ID NOS 5 - 8 and 15 - 16, wherein the oligonucleotide has two target gene sites, and a reporter dye is positioned at a 5' direction of the two target gene sites and a quencher is positioned at a 3' direction of the two target gene sites, and a base of the sequence in which the corresponding reporter dye or quencher is located is modified from thymine to amino-C6 (or C2)-deoxythymine, or from adenine, thymine, guanine, cytosine or uridine to amino-C6-deoxyribose; such that all or a part of the sequences of said oligonucleotide form a double-strand at a certain temperature or lower, the oligonucleotide having one to four bubble structures that are formed between the two target gene sites; and wherein there is a 21~33 mer interval between the reporter dye and the quencher.
A cart for assisting in transferring mailpieces for a postal sorting machine having a row of sorting outlets at each of which the mailpieces are stacked on edge on a work surface, said cart for assisting in transferring mailpieces including a support defining the bottom of a filling zone suitable for receiving a tray to be filled with stacked mailpieces, said cart for assisting in transferring mailpieces being characterized in that it includes a back plate carrying guide means designed to co-operate with a longitudinal runner provided on said sorting machine for the purpose of guiding said cart for assisting in transferring mailpieces along said work surface, in that said back plate is extended by a transfer ramp inclined relative to said back plate with which it forms an acute angle and designed to bridge over the edge of the work surface to come flush with said work surface from above, regardless of the longitudinal position of said cart for assisting in transferring mailpieces.
A cartridge system comprising: a cartridge housing comprising: at least one sample inlet; a plurality of storage chambers; a plurality of reaction chambers; and a fluidic network connecting the at least one sample inlet, at least a portion of the plurality of storage chambers, and at least a portion of the plurality of reaction chambers to a first plurality of ports located on an inner surface of the cartridge housing; and a hollow transfer module, disposed within the cartridge housing, comprising a compliant jacket around a housing and a second plurality of ports along an outer surface of the transfer module that lead to a central chamber of the transfer module, the transfer module configured to move laterally along a length of the cartridge housing, wherein lateral movement of the transfer module aligns at least a portion of the first plurality of ports with at least a portion of the second plurality of ports. a cartridge housing comprising: at least one sample inlet; a plurality of storage chambers; a plurality of reaction chambers; and a fluidic network connecting the at least one sample inlet, at least a portion of the plurality of storage chambers, and at least a portion of the plurality of reaction chambers to a first plurality of ports located on an inner surface of the cartridge housing; and at least one sample inlet; a plurality of storage chambers; a plurality of reaction chambers; and a fluidic network connecting the at least one sample inlet, at least a portion of the plurality of storage chambers, and at least a portion of the plurality of reaction chambers to a first plurality of ports located on an inner surface of the cartridge housing; and a hollow transfer module, disposed within the cartridge housing, comprising a compliant jacket around a housing and a second plurality of ports along an outer surface of the transfer module that lead to a central chamber of the transfer module, the transfer module configured to move laterally along a length of the cartridge housing, wherein lateral movement of the transfer module aligns at least a portion of the first plurality of ports with at least a portion of the second plurality of ports.
A method for wireless communication, comprising: providing L signaling symbols to each one of a plurality of spreaders (S 1...S M), wherein L > 1; with each one of the plurality of spreaders (S 1...S M), spreading said L signaling symbols to obtain a respective set of L output symbols, each set of L output symbols being obtained by spreading the L signaling symbols with a spreading matrix corresponding to the respective spreader; and mapping the respective set of L output symbols from each spreader to L resource units within one of multiple time frequency blocks corresponding to the respective spreader. providing L signaling symbols to each one of a plurality of spreaders (S 1...S M), wherein L > 1; with each one of the plurality of spreaders (S 1...S M), spreading said L signaling symbols to obtain a respective set of L output symbols, each set of L output symbols being obtained by spreading the L signaling symbols with a spreading matrix corresponding to the respective spreader; and mapping the respective set of L output symbols from each spreader to L resource units within one of multiple time frequency blocks corresponding to the respective spreader.
Pivot joint for adjusting a functional part, in particular a head part, a foot part or an armrest, of a piece of furniture, in particular a piece of seating furniture and/or reclining furniture, with a mounting lever for mounting of the swivel joint on the furniture and a swivel lever for supporting and adjusting the functional part, wherein the mounting lever and the swivel lever are connected to one another in a manner pivotable from an initial position to an end position about a swivel axis in an adjusting direction, wherein the swivel lever is lockable in a plurality of locking positions between the initial position and the end position by a blocking clamping engagement of at least one clamping element in a tapered clamping gap formed between a shaft and a collar at least partially receiving the shaft during adjustment in a return direction opposite to the adjustment direction, wherein the shaft and the collar are adjustable relative to one another from a setting position into a reset position, and wherein the shaft and the collar are held in the reset position in a form-fitting and/or force-fitting manner in alignment with one another during adjustment in the reset direction in such a way that the clamping element is not held clampingly with a clamping force a clearance in the clamping gap and/or outside the clamping gap, characterized in that the collar and the shaft in the reset position are connected to one another in a form fit or friction fit in such a way that when they are adjusted in the return direction, the collar and the shaft rotate jointly around the swivel axis.
Floor cover for preventing growth under fences between the uprights thereof, the floor cover being composed of a plurality of laths, preferably of plastic, which telescopically engage each other, characterized in that one lath is formed as a sleeve with open ends in which two pull-out laths are arranged which - when the floor cover lies on the floor - are superimposed and each can be pulled out from one end of the sleeve.
Device for multipoint acquisition/distribution of fluid comprising at least two internal ducts (C1 to C9) arranged in a cylindrical body, characterized in that these ducts follow helicoidal traces in a cylindrical section, having the same axis as the one of the body, in which several acquisitions/distributions of fluid are carried out by propagation in the ducts (C1 to C9) from inlet/outlet orifices (01 to 09) formed on an external radial skin of the cylindrical section of the body in regards of the ducts (C1 to C9) in several parallel planes at different heights (H1, H2, H3) along the axis of the body, the position of the orifices (01 to 09) and the pitch of the ducts (C1 to C9) being determined so that at least one orifice corresponds to a one and only internal duct.
A compound of Formula: or a salt thereof, wherein l is selected from 1, 2, 3, 4, and 5; m is selected from 5, 6, 7, 8, and 9; M 1 is a bond or M'; M and M' are independently selected from -C O-, -OC -, -C N(R')-, -P (OR')O-, -S-S-, an aryl group, and a heteroaryl group; each R' is linear C 1-18 alkyl; R 4 is -(CH 2) n Q, in which Q is OH or -OC N 2, and n is selected from 1, 2, 3, 4, and 5; each R is independently selected from the group consisting of C 1-3 alkyl, C 2-3 alkenyl, and H; and R 2 and R 3 are independently selected from the group consisting of H, C 1-14 alkyl, and C 2-14 alkenyl. l is selected from 1, 2, 3, 4, and 5; m is selected from 5, 6, 7, 8, and 9; M 1 is a bond or M'; M and M' are independently selected from -C O-, -OC -, -C N(R')-, -P (OR')O-, -S-S-, an aryl group, and a heteroaryl group; each R' is linear C 1-18 alkyl; R 4 is -(CH 2) n Q, in which Q is OH or -OC N 2, and n is selected from 1, 2, 3, 4, and 5; each R is independently selected from the group consisting of C 1-3 alkyl, C 2-3 alkenyl, and H; and R 2 and R 3 are independently selected from the group consisting of H, C 1-14 alkyl, and C 2-14 alkenyl.
Assembly for packaging and applying a cosmetic product chosen from mascaras, glosses, nail varnishes and foundations and comprising at least one volatile solvent, said packaging and application assembly comprising, for the one part, a body forming a reservoir containing the cosmetic product to be applied and a free edge of which delimits an opening, said body being equipped with a closing member provided to close the opening of said reservoir in a removable manner, and, for the other part, an applicator comprising an applicator member (22, 201, 211, 221, 231, 240, 250, 260, 270, 300) having a, preferably elongate, main body bearing a set of protruding application elements (24, 202, 212, 222, 224, 261, 302, 303) that define between one another a plurality of spaces (25, 203, 213, 223, 263) for loading and applying the cosmetic product, said applicator being able to move between a first position, known as the pick-up position, in which the applicator member is situated inside the reservoir and is able to be brought at least partially into contact with the cosmetic product intended to be contained in the reservoir, and a position, known as the application position, in which the applicator member is removed from the reservoir and can be brought into contact with a part of the human body, said packaging and application assembly being characterized in that at least some of the spaces for loading and applying cosmetic product are delimited by at least one surface produced from an open-cell porous material that mainly and preferentially absorbs the volatile solvent of the cosmetic product with respect to the active components of said cosmetic product so that the ratio between the mass concentration of the solvent in the cosmetic product and the mass concentration of the solvent in the liquid absorbed in the porous material is greater than 1.3.
A method for distinguishing isobaric amino acids and amino acid combinations of isoleucine and leucine; asparagine and glycine-glycine; glutamine and glycine-alanine; and/or glutamine and alanine-glycine or glycine-alanine, during polypeptide sequencing, the method comprising: obtaining a peptide of interest and/or digesting a polypeptide of interest with a protease or a chemical cleavage method to produce shorter peptides; reacting the obtained and/or generated peptides with a coupling reagent capable of derivatizing the free C-terminal carboxylic acid function of the peptides, under conditions to add a basic functional group (a single positive charge or multiple positive charges); selecting a charge state of 2+ or more, and fragmenting the derivatized peptides in a mass spectrometer under conditions effective to generate at least w ions; and detecting said w ions by mass spectrometry, and identifying derivatized peptides which incorporate the additional mass of said basic functional group; wherein positive charges are added to the free C-terminal carboxylic acid function of the peptide and/or polypeptide, and said w ions are analyzed to distinguish between the isobaric amino acids and amino acid combinations of: isoleucine and leucine; asparagine and glycine-glycine; glutamine and glycine-alanine; and/or glutamine and alanine-glycine. obtaining a peptide of interest and/or digesting a polypeptide of interest with a protease or a chemical cleavage method to produce shorter peptides; reacting the obtained and/or generated peptides with a coupling reagent capable of derivatizing the free C-terminal carboxylic acid function of the peptides, under conditions to add a basic functional group (a single positive charge or multiple positive charges); selecting a charge state of 2+ or more, and fragmenting the derivatized peptides in a mass spectrometer under conditions effective to generate at least w ions; and detecting said w ions by mass spectrometry, and identifying derivatized peptides which incorporate the additional mass of said basic functional group;
A system comprising: a secure processing engine (110, 210) to store a host key; and an integrated circuit (120, 220, 500, 600) in a single package, the integrated circuit (120, 220, 500, 600) including: a firmware engine (121, 221, 510, 610) to execute firmware instructions, a one-time-programmable, OTP, memory (122, 222) unreadable by the firmware engine (121, 221, 510, 610), the OTP memory (122, 222) to store the host key, a security engine (123, 223, 530, 630) to encrypt and decrypt communications between the firmware engine (121, 221, 510, 610) and the secure processing engine (110, 210) based on the host key, wherein the security engine (123, 223, 530, 630) is to receive a message to be encrypted from the firmware engine (121, 221, 510, 610) and to store an encrypted version of the message in a memory location readable by the firmware engine (121,221,510,610). a secure processing engine (110, 210) to store a host key; and an integrated circuit (120, 220, 500, 600) in a single package, the integrated circuit (120, 220, 500, 600) including: a firmware engine (121, 221, 510, 610) to execute firmware instructions, a one-time-programmable, OTP, memory (122, 222) unreadable by the firmware engine (121, 221, 510, 610), the OTP memory (122, 222) to store the host key, a security engine (123, 223, 530, 630) to encrypt and decrypt communications between the firmware engine (121, 221, 510, 610) and the secure processing engine (110, 210) based on the host key, wherein the security engine (123, 223, 530, 630) is to receive a message to be encrypted from the firmware engine (121, 221, 510, 610) and to store an encrypted version of the message in a memory location readable by the firmware engine (121,221,510,610). a firmware engine (121, 221, 510, 610) to execute firmware instructions, a one-time-programmable, OTP, memory (122, 222) unreadable by the firmware engine (121, 221, 510, 610), the OTP memory (122, 222) to store the host key, a security engine (123, 223, 530, 630) to encrypt and decrypt communications between the firmware engine (121, 221, 510, 610) and the secure processing engine (110, 210) based on the host key, wherein the security engine (123, 223, 530, 630) is to receive a message to be encrypted from the firmware engine (121, 221, 510, 610) and to store an encrypted version of the message in a memory location readable by the firmware engine (121,221,510,610).
Water-conducting domestic appliance, in particular laundry treatment device for washing and/or drying laundry, having a switching valve, which has a valve chamber, into which an input opens, wherein the valve chamber has a first output with a first valve seat surface and a second output with a second valve seat surface, and wherein the switching valve has a magnetic actuation facility for optionally controlling a fluid flow from the input to the first output or the second output, characterised in that the switching valve has a spherical valve closing element which can be actuated by the magnetic actuation facility, said valve closing element interacting on the one hand with the first valve seat surface and on the other hand with the second valve seat surface to form a seal seat.
A method for calibrating sensor data collected from a characteristic sensor comprising: obtaining a calibration reference value from another characteristic measuring device for the characteristic sensor; calculating a current calibration factor based on the calibration reference value and a current sensor data point; comparing a rate of change parameter relating to the current sensor data point to a threshold value; characterised by reducing a weight of the current calibration factor if the rate of change parameter is equal to or exceeds the threshold value; determining a calibration formula using the weighted current calibration factor; and interpreting the collected sensor data using the calibration formula. obtaining a calibration reference value from another characteristic measuring device for the characteristic sensor; calculating a current calibration factor based on the calibration reference value and a current sensor data point; comparing a rate of change parameter relating to the current sensor data point to a threshold value; characterised by reducing a weight of the current calibration factor if the rate of change parameter is equal to or exceeds the threshold value; determining a calibration formula using the weighted current calibration factor; and interpreting the collected sensor data using the calibration formula.
A hand held controller for a games console comprising: an outer case; a plurality of controls (2, 3, 4, 5, 6, 7, 8, 9) located on a front end and/or top of the controller; at least one additional control (11A, 11B, 11C, 11D) located on a back of the controller; a control unit for controlling a mode of operation of the controller; and at least one magnetic sensor in communication with the control unit; the control unit being configured to receive a signal from the at least one magnetic sensor in dependence upon a magnetic field being detected by the at least one magnetic sensor and the control unit being configured to determine a mode of operation of the controller in dependence upon the signal received from the at least one magnetic sensor, wherein the controller enters a programmable mode in which the controller is configurable when the at least one magnetic sensor detects a correctly aligned magnetic field and wherein in the programmable mode, functions operated by the at least one additional control (11A, 11B, 11C, 11D) located on the back of the controller can be assigned to replicate a function operated by one of the plurality of controls (2, 3, 4, 5, 6, 7, 8, 9) located on a front end and/or top of the controller. an outer case; a plurality of controls (2, 3, 4, 5, 6, 7, 8, 9) located on a front end and/or top of the controller; at least one additional control (11A, 11B, 11C, 11D) located on a back of the controller; a control unit for controlling a mode of operation of the controller; and at least one magnetic sensor in communication with the control unit; the control unit being configured to receive a signal from the at least one magnetic sensor in dependence upon a magnetic field being detected by the at least one magnetic sensor and the control unit being configured to determine a mode of operation of the controller in dependence upon the signal received from the at least one magnetic sensor, wherein the controller enters a programmable mode in which the controller is configurable when the at least one magnetic sensor detects a correctly aligned magnetic field and wherein in the programmable mode, functions operated by the at least one additional control (11A, 11B, 11C, 11D) located on the back of the controller can be assigned to replicate a function operated by one of the plurality of controls (2, 3, 4, 5, 6, 7, 8, 9) located on a front end and/or top of the controller.
Nozzle assembly for a combustion chamber of an engine, comprising a plurality of nozzles (2A, 2B, 2C) arranged next to one another for introducing fuel into the combustion chamber, wherein each nozzle (2A, 2B, 2C) has a nozzle outlet opening and a fuel duct for conveying fuel in the direction of the nozzle outlet opening, wherein at least two different types of nozzles (2A, 2B, 2C) are provided, wherein - the nozzles (2A, 2B, 2C) of different types have nozzle outlet openings with an identical cross section, and - to specify different through-flow rates of fuel through the fuel ducts of the different types of nozzles (2A, 2B, 2C), a cross section of a fuel duct of one type of nozzle (2A, 2B, 2C) is different from a cross section of a fuel duct of another type of nozzle (2B, 2C, 2A), characterized in that - a through-flow controller is assigned to at least one type of nozzle and connected upstream of the fuel duct and by means of which a quantity of fuel that can be supplied to the fuel duct can be set, wherein the through-flow controller is assigned to the type of nozzle whose fuel duct has the largest cross section. - the nozzles (2A, 2B, 2C) of different types have nozzle outlet openings with an identical cross section, and - to specify different through-flow rates of fuel through the fuel ducts of the different types of nozzles (2A, 2B, 2C), a cross section of a fuel duct of one type of nozzle (2A, 2B, 2C) is different from a cross section of a fuel duct of another type of nozzle (2B, 2C, 2A), characterized in that - a through-flow controller is assigned to at least one type of nozzle and connected upstream of the fuel duct and by means of which a quantity of fuel that can be supplied to the fuel duct can be set, wherein the through-flow controller is assigned to the type of nozzle whose fuel duct has the largest cross section.
A method for determining whether a hepatitis B patient has an improved chance of a positive outcome of hepatitis B treatment, as compared to the mean hepatitis B patient population, comprising determining whether a nucleic acid-containing sample of said hepatitis B patient comprises the G allele of SNP rs12356193.