An ophthalmic imaging system (10; 10-1; 10-2) for generating an image of a region of an eye of a subject, the ophthalmic imaging system comprising: an ocular imaging device operable to acquire an ocular image of the region; a control module (2; 2-1; 2-2) configured to: control the ocular imaging device to acquire, from a first viewpoint relative to the region, a first ocular image of the region having an image artefact caused by obstruction from imaging of a part of the region by an object between the ocular imaging device and the region during acquisition of the first ocular image; and control the ocular imaging device to acquire a second ocular image from a predetermined second viewpoint that is different from the first viewpoint, the second ocular image showing at least a portion of the part of the region that was obstructed by the object from being imaged during acquisition of the first ocular image; and an image data processing module configured to combine image data of the first ocular image with image data of the second ocular image to generate an enhanced ocular image having one of: no image artefact caused by obstruction from imaging of a part of the region by the object between the ocular imaging device and the region during acquisition of the first ocular image or the second ocular image; or an image artefact that is based on at least one of the image artefact in the first ocular image, or an image artefact in the second ocular image caused by obstruction from imaging of a part of the region by the object between the ocular imaging device and the region during acquisition of the second ocular image, and is smaller in relation to at least one of the image artefact in the first ocular image or the image artefact in the second ocular image. an ocular imaging device operable to acquire an ocular image of the region; a control module (2; 2-1; 2-2) configured to: control the ocular imaging device to acquire, from a first viewpoint relative to the region, a first ocular image of the region having an image artefact caused by obstruction from imaging of a part of the region by an object between the ocular imaging device and the region during acquisition of the first ocular image; and control the ocular imaging device to acquire a second ocular image from a predetermined second viewpoint that is different from the first viewpoint, the second ocular image showing at least a portion of the part of the region that was obstructed by the object from being imaged during acquisition of the first ocular image; and control the ocular imaging device to acquire, from a first viewpoint relative to the region, a first ocular image of the region having an image artefact caused by obstruction from imaging of a part of the region by an object between the ocular imaging device and the region during acquisition of the first ocular image; and control the ocular imaging device to acquire a second ocular image from a predetermined second viewpoint that is different from the first viewpoint, the second ocular image showing at least a portion of the part of the region that was obstructed by the object from being imaged during acquisition of the first ocular image; and an image data processing module configured to combine image data of the first ocular image with image data of the second ocular image to generate an enhanced ocular image having one of: no image artefact caused by obstruction from imaging of a part of the region by the object between the ocular imaging device and the region during acquisition of the first ocular image or the second ocular image; or an image artefact that is based on at least one of the image artefact in the first ocular image, or an image artefact in the second ocular image caused by obstruction from imaging of a part of the region by the object between the ocular imaging device and the region during acquisition of the second ocular image, and is smaller in relation to at least one of the image artefact in the first ocular image or the image artefact in the second ocular image. no image artefact caused by obstruction from imaging of a part of the region by the object between the ocular imaging device and the region during acquisition of the first ocular image or the second ocular image; or an image artefact that is based on at least one of the image artefact in the first ocular image, or an image artefact in the second ocular image caused by obstruction from imaging of a part of the region by the object between the ocular imaging device and the region during acquisition of the second ocular image, and is smaller in relation to at least one of the image artefact in the first ocular image or the image artefact in the second ocular image.