A delivery device for the administration of a powdered pharmaceutical product comprising a first component and a second component: the first component having an ejection port at one end, a chamber holding a reservoir of diluent, and an activating means to facilitate the flow of said diluent through said ejection port; and the second component containing a lyophilized drug powder, said second component capable of engaging said first component at one end and engaging a standard type needle at the opposing end, said second component comprising a one-way valve mechanism formed as a plunger assembly which upon activation of said first component, allows the diluent ejected from said first component to flow into said second component and encounter the powder in said second component, rapidly reconstitute and pass through said needle characterised in that said second component is a container closure assembly comprising: a) a hard plug component comprising: a female luer slip fitting cavity to allow for friction fit of a standard type luer slip syringe; a circular cavity that can accommodate the standard type luer slip syringe; and a depression and female portion that can be mated with the sealing conical mound of the soft plug component to create a one way valve; b) a soft plug component comprising: a hollow inside capable of accepting said hard plug component to create the plunger assembly; vent holes which allow for vapors to escape during lyophilization processes; sealing ridges which serve to seal said soft plug component against the interior wall of the product container component; and a sealing conical mound that can be mated with said depression and female portion of said hard plug component to create a one way valve; and c) a product container component comprising: an open end having a chamber capable of holding a liquid to be lyophilized and capable of receiving said plunger assembly; and an opposing neck area having a detachable base to allow for attachment of a standard type luer slip or luer lock syringe needle, and in that in use there is no air space between the lyophilized drug powder and the plunger assembly. the first component having an ejection port at one end, a chamber holding a reservoir of diluent, and an activating means to facilitate the flow of said diluent through said ejection port; and the second component containing a lyophilized drug powder, said second component capable of engaging said first component at one end and engaging a standard type needle at the opposing end, said second component comprising a one-way valve mechanism formed as a plunger assembly which upon activation of said first component, allows the diluent ejected from said first component to flow into said second component and encounter the powder in said second component, rapidly reconstitute and pass through said needle a) a hard plug component comprising: a female luer slip fitting cavity to allow for friction fit of a standard type luer slip syringe; a circular cavity that can accommodate the standard type luer slip syringe; and a depression and female portion that can be mated with the sealing conical mound of the soft plug component to create a one way valve; a female luer slip fitting cavity to allow for friction fit of a standard type luer slip syringe; a circular cavity that can accommodate the standard type luer slip syringe; and a depression and female portion that can be mated with the sealing conical mound of the soft plug component to create a one way valve; b) a soft plug component comprising: a hollow inside capable of accepting said hard plug component to create the plunger assembly; vent holes which allow for vapors to escape during lyophilization processes; sealing ridges which serve to seal said soft plug component against the interior wall of the product container component; and a sealing conical mound that can be mated with said depression and female portion of said hard plug component to create a one way valve; and a hollow inside capable of accepting said hard plug component to create the plunger assembly; vent holes which allow for vapors to escape during lyophilization processes; sealing ridges which serve to seal said soft plug component against the interior wall of the product container component; and a sealing conical mound that can be mated with said depression and female portion of said hard plug component to create a one way valve; and c) a product container component comprising: an open end having a chamber capable of holding a liquid to be lyophilized and capable of receiving said plunger assembly; and an opposing neck area having a detachable base to allow for attachment of a standard type luer slip or luer lock syringe needle, and an open end having a chamber capable of holding a liquid to be lyophilized and capable of receiving said plunger assembly; and an opposing neck area having a detachable base to allow for attachment of a standard type luer slip or luer lock syringe needle, and