mhurhangee/ep-ind-claims huggingface dataset:
A compound selected from the group consisting of wherein X is lysine; L is a bond or a linker; each PEG is a polyethyleneglycol polymer, wherein each PEG polymer has a molecular weight of 1-100 kDa; each R' is selected from the group consisting of cholic acid, (3α, 5β, 7α, 12α)-7,12-dihydroxy-3-(2,3-dihydroxy-1-propoxy)-cholic acid (CA-4OH), (3α, 5β, 7α, 12α)-7-hydroxy-3,12-di(2,3-dihydroxy-1-propoxy)-cholic acid (CA-5OH) and (3α, 5β, 7α, 12α)-7,12-dihydroxy-3-(3-amino-2-hydroxy-1-propoxy)-cholic acid (CA-3OH-NH 2); and each R" is selected from the group consisting of cholesterol formate, doxorubicin, and rhein (Rh). X is lysine; L is a bond or a linker; each PEG is a polyethyleneglycol polymer, wherein each PEG polymer has a molecular weight of 1-100 kDa; each R' is selected from the group consisting of cholic acid, (3α, 5β, 7α, 12α)-7,12-dihydroxy-3-(2,3-dihydroxy-1-propoxy)-cholic acid (CA-4OH), (3α, 5β, 7α, 12α)-7-hydroxy-3,12-di(2,3-dihydroxy-1-propoxy)-cholic acid (CA-5OH) and (3α, 5β, 7α, 12α)-7,12-dihydroxy-3-(3-amino-2-hydroxy-1-propoxy)-cholic acid (CA-3OH-NH 2); and each R" is selected from the group consisting of cholesterol formate, doxorubicin, and rhein (Rh).
A fluidic actuator comprising: - a fluid nozzle for delivering fluid; - a tube having an open end and a closed end, the open end spaced from the fluid nozzle; - a pair of electrodes mounted in the tube and spaced apart to create a spark gap therebetween; and - a voltage source arranged to supply a voltage across the pair of electrodes wherein the voltage causes plasma formation in the spark gap which forms a barrier to fluid flow thereby shortening an effective length (x) of the tube. - a fluid nozzle for delivering fluid; - a tube having an open end and a closed end, the open end spaced from the fluid nozzle; - a pair of electrodes mounted in the tube and spaced apart to create a spark gap therebetween; and - a voltage source arranged to supply a voltage across the pair of electrodes wherein the voltage causes plasma formation in the spark gap which forms a barrier to fluid flow thereby shortening an effective length (x) of the tube.
A functional article comprising a waterproof breathable polymer membrane, where the functional article consists of the waterproof breathable polymer membrane and where the functional article has no other layer; where the functional article is selected from the group consisting of functional clothing item; functional footwear item; functional object selected from the group consisting of bag, backpack or tent; swimwear item; and clothing for water sport, where the polymer membrane has an elongation at break of more than 100% as measured to DIN 53504; where the polymer membrane is generated from a solution comprising at least one thermoplastic polymer and at least one additive selected from the group consisting of mono-, di- and trialkanols which have no other functional groups by formation of a film from the solution and contacting of the film with a mixture comprising a coagulant selected from the group of liquid water, water vapor, alcohols or mixtures thereof, and has pores having a mean pore diameter in the range from 0.001 μm to 0.8 μm, determined by Hg porosimetry according to DIN 66133; and where the polymer membrane comprises at least one thermoplastic polymer selected from the group consisting of polyurethane, polyester, polyetherester, polyesterester, polyamide, polyetheramide, polybutadiene-styrene and ethylenevinyl acetate.
Method for producing components made from a lightweight austenitic steel, which is metastable in the initial state, by forming a steel sheet, a blank or a tube in one or more steps, having a temperature-dependent TRIP- and/or TWIP effect during the forming, characterised in that, in order to achieve a particularly high toughness of the component, the forming is undertaken at a temperature above room temperature, which avoids the TRIP-/TWIP effect, at 40 to 160°C, and in order to achieve a high component strength, the forming is undertaken at a temperature below room temperature, which reinforces the TRIP-/TWIP effect, at -65 to 0°C, and in that the forming takes place in several steps, in the individual steps the forming temperature and/or the degree of deformation and/or the deformation speed being varied, the forming being effected in the first step or in further steps at a temperature which avoids the deformation-induced TRIP-/TWIP effect above room temperature and in the final step the forming being effected at a temperature below room temperature, which reinforces the TRIP-/TWIP effect, the entire component being able to be subjected to the corresponding forming temperature, or the component being formed with partially different temperatures, so that different material properties can be produced within one component.
A kit for use in hip arthroplasty comprising: an acetabular shell which has a shell locking section, and a liner adapted to be inserted into the shell, the liner including an inner surface and an outer surface and a rim extending between the inner surface and the outer surface, in which the inner surface is generally concave, and the outer surface includes a liner locking section, in which the shell locking section and the liner locking section are self-locking tapers, and characterised in that the outer surface also includes a composite-curved section extending from the locking section at a first transition point when the liner is viewed in cross-section, the composite-curved section is tangential to the locking section and includes a radial portion having a radius extending from the locking section at the first transition point, and in which the composite-curved section also includes a tangential portion that is a straight line and that is tangential to the radial portion at a second transition point. an acetabular shell which has a shell locking section, and a liner adapted to be inserted into the shell, the liner including an inner surface and an outer surface and a rim extending between the inner surface and the outer surface, in which the inner surface is generally concave, and the outer surface includes a liner locking section, in which the shell locking section and the liner locking section are self-locking tapers, and characterised in that the outer surface also includes a composite-curved section extending from the locking section at a first transition point when the liner is viewed in cross-section, the composite-curved section is tangential to the locking section and includes a radial portion having a radius extending from the locking section at the first transition point, and in which the composite-curved section also includes a tangential portion that is a straight line and that is tangential to the radial portion at a second transition point.
Closure cap having a substantially planar cap element having an angled retaining element and a curved spring clip which projects from the planar cap element, characterized in that the spring clip, proceeding from the cap element, has two first legs (10, 11) which are spaced apart and obliquely disposed in such a manner that they are oriented so as to face away from one another, wherein the two first legs are interconnected by a bracket, wherein the bracket is configured so as to be M-shaped from two outer second legs (13, 14) and two inner third legs (15, 16) wherein the outer second legs (13, 14) are inclined towards one another and the two third legs (15, 16) are inclined away from one another, such that the M-shaped contour is produced.
A pipe component with an outer pipe element and at least one inner pipe element arranged inside the outer pipe element, wherein the outer pipe element is formed as flexible pipe element with a plurality of projections, in particular corrugations, and/or at least one corrugated portion, wherein on at least one point the outer pipe element and the at least one inner pipe element each have a projection (11, 12) pointing to the outside in radial direction, wherein the outside of the projection of the at least one inner pipe element at least partly flatly rests against the inside of the projection of the outer pipe element or against the inside of the projection of another inner pipe element, so that by means of the projections (11, 12) a connection exists between the at least one inner pipe element and the outer pipe element, characterized in that the at least one connection is formed as positive and/or non-positive connection.
A moisture-curable hot melt adhesive comprising an alicyclic urethane prepolymer having isocyanate group(s) at the ends, wherein the alicyclic urethane prepolymer comprises a chemical structure derived from a polycarbonate polyol, and at least one of the isocyanate group(s) at the ends is combined with a chemical structure derived from an aromatic ring, and wherein the alicyclic urethane prepolymer comprises a urethane prepolymer obtainable by mixing an alicyclic polycarbonate urethane polyol with an aromatic isocyanate, and the alicyclic polycarbonate urethane polyol comprises an alicyclic polyol obtainable by mixing a polycarbonate polyol with an alicyclic isocyanate.
Power shift transmission having an input shaft, a first output shaft which is arranged coaxially with respect to the input shaft, a planetary gear mechanism with a planetary carrier which is connected to the input shaft and at least one multi-step planet set, the multi-step planet set meshing on the input side and on the output side with in each case one sun gear (52, 44), and at least two shifting elements (24, 26), characterized in that the first output shaft can be connected by way of a first shifting element to the output-side sun gear of the multi-step planet set, and the first output shaft can be connected by way of a second shifting element directly to the input shaft, the input-side sun gear of the multi-step planet set being connected fixedly to a housing part of the power shift transmission so as to rotate with it.
A timepiece case, comprising: a fitting surface facing a lid member when the lid member is fitted to the timepiece case, the timepiece case being formed of ceramics, which is any one selected from aluminum oxide-based ceramics, zirconium oxide-based ceramics and silicon nitride-based ceramics, an arithmetic mean roughness Ra, as defined in JIS B 0601, of the fitting surface which is obtained from a roughness profile, being 0.6 um or less, a reduced peak height Rpk, as defined in JIS B 0671-2, of the fitting surface which is obtained from the roughness profile, being 0.9 um or less. a fitting surface facing a lid member when the lid member is fitted to the timepiece case, the timepiece case being formed of ceramics, which is any one selected from aluminum oxide-based ceramics, zirconium oxide-based ceramics and silicon nitride-based ceramics, an arithmetic mean roughness Ra, as defined in JIS B 0601, of the fitting surface which is obtained from a roughness profile, being 0.6 um or less, a reduced peak height Rpk, as defined in JIS B 0671-2, of the fitting surface which is obtained from the roughness profile, being 0.9 um or less.
An oral care composition comprising at least one carbon dioxide source, at least one acid source, at least one abrasive and one or more pharmaceutically acceptable excipients wherein the at least one carbon dioxide source is a bicarbonate salt of an alkali or alkaline earth metal, a carbonate of an alkali or alkaline earth metal or a mixture thereof, the at least one acid source is a pharmaceutically acceptable organic acid, inorganic acid, salt or partial salt of an organic or inorganic acid or a mixture thereof, and the at least one abrasive is co-processed abrasive and the co-processed abrasive is co-processed calcium silicate, co-processed magnesium silicate or a combination thereof.
A turboshaft engine (10, 100) comprising a low-pressure compressor, a high-pressure compressor, a low-pressure turbine, a high-pressure turbine, and regulator means for regulating the speed of rotation of the low-pressure turbine to a speed that is substantially constant, wherein the low-pressure turbine is coupled by a first shaft to the high-pressure compressor, while the high-pressure turbine is coupled by a second shaft to the low-pressure compressor, the first shaft passes coaxially inside the second shaft, the first and second shafts (24, 26) defining an axial direction, characterized in that the high-pressure compressor, the low-pressure compressor, the high-pressure turbine, and the low-pressure turbine are arranged in that order along the axial direction.
A static spray mixer for the mixing and spraying of at least two flowable components having a tubular mixer housing which extends in the direction of a longitudinal axis up to a distal end which has an outlet opening for the components, having at least one mixing element arranged in the mixer housing for the mixing of the components as well as having an atomization sleeve which has an inner surface which surrounds the mixer housing in its end region, wherein the atomization sleeve has an inlet channel for a pressurized atomization medium, wherein a plurality of grooves are provided in the outer surface of the mixer housing or in the inner surface of the atomization sleeve which respectively extend toward the distal end and which form separate flow channels between the atomization sleeve and the mixer housing through which the atomization medium can flow from the inlet channel of the atomization sleeve to the distal end of the mixer housing, characterized in that the inlet channel is arranged asymmetrically with respect to the longitudinal axis such that the inlet channel has a central axis and is arranged such that the central axis does not intersect the longitudinal axis, but rather has a perpendicular spacing (e) from the longitudinal axis.
A display apparatus comprising: a chassis disposed at a rear side of a display panel to support the display panel; a cover coupled to a rear side of the chassis to cover the chassis; a mounting unit provided on the chassis and configured to mount the display apparatus and comprising a plurality of mounting holes, each configured to be coupled with a fastening member passing through the cover; and a plurality of concealing units provided on the cover, wherein the plurality of concealing units are configured to cover respective ones of the plurality of mounting holes and are removable from the cover to expose the plurality of mounting holes, wherein each of the plurality of concealing units comprises: a concealing portion formed integrally with the cover to conceal the respective ones of the plurality of mounting holes of the mounting unit; and a removing guide portion provided to facilitate removal of the concealing portion, and wherein the removing guide portion comprises at least two slits formed as a cut out along a circumference of the concealing portion, and at least one guide groove formed as a notch on the inner surface of the cover along the circumference of the concealing portion where the at least two slits are not formed. a chassis disposed at a rear side of a display panel to support the display panel; a cover coupled to a rear side of the chassis to cover the chassis; a mounting unit provided on the chassis and configured to mount the display apparatus and comprising a plurality of mounting holes, each configured to be coupled with a fastening member passing through the cover; and a plurality of concealing units provided on the cover, wherein the plurality of concealing units are configured to cover respective ones of the plurality of mounting holes and are removable from the cover to expose the plurality of mounting holes, wherein each of the plurality of concealing units comprises: a concealing portion formed integrally with the cover to conceal the respective ones of the plurality of mounting holes of the mounting unit; and a removing guide portion provided to facilitate removal of the concealing portion, and a concealing portion formed integrally with the cover to conceal the respective ones of the plurality of mounting holes of the mounting unit; and a removing guide portion provided to facilitate removal of the concealing portion, and wherein the removing guide portion comprises at least two slits formed as a cut out along a circumference of the concealing portion, and at least one guide groove formed as a notch on the inner surface of the cover along the circumference of the concealing portion where the at least two slits are not formed.
A process for the production of a water-soluble composition comprising a water-insoluble sartan, wherein the water-insoluble sartan has a solubility in water of less than 10 g/L, which comprises the steps of: a) providing a mixture consisting essentially of: i) the water-insoluble sartan, ii) a water-soluble carrier material, which consists essentially of at least one surfactant and at least one polymer, iii) a solvent for each of the sartan and the carrier material, wherein the at least one surfactant is selected from the group consisting of: alkoxylated non-ionic surfactants, phenol ethoxylates, alkyl sulphonates, ester surfactants and cationic surfactants, wherein the at least one polymer is selected from the group consisting of: polyethylene glycol, polyvinylpyrrolidone, poly(2-ethyl-2-oxazaline), polyvinyl alcohol, hydroxypropyl cellulose, hydroxypropylmethyl cellulose and alginate, and wherein the solvent for the water-soluble carrier material is water and the solvent for the water-soluble sartan is non-aqueous and selected from the group consisting of: dichloromethane, chloroform, methanol, ethanol, isopropanol, isobutanol, formic acid, acetic acid, formamide, N,N -dimethylformamide, acetonitrile, ethyl acetate, methyl ethyl ketone, acetone, dialkyl sulphoxide and tetrahydrofuran, and b) spray-drying the mixture to remove each solvent and to thereby obtain a substantially solvent-free nano-dispersion of the water-insoluble sartan in the carrier material, wherein the weight ratio of the sartan to carrier material is from 1:500 to 1:1. a) providing a mixture consisting essentially of: i) the water-insoluble sartan, ii) a water-soluble carrier material, which consists essentially of at least one surfactant and at least one polymer, iii) a solvent for each of the sartan and the carrier material, wherein the at least one surfactant is selected from the group consisting of: alkoxylated non-ionic surfactants, phenol ethoxylates, alkyl sulphonates, ester surfactants and cationic surfactants, wherein the at least one polymer is selected from the group consisting of: polyethylene glycol, polyvinylpyrrolidone, poly(2-ethyl-2-oxazaline), polyvinyl alcohol, hydroxypropyl cellulose, hydroxypropylmethyl cellulose and alginate, and wherein the solvent for the water-soluble carrier material is water and the solvent for the water-soluble sartan is non-aqueous and selected from the group consisting of: dichloromethane, chloroform, methanol, ethanol, isopropanol, isobutanol, formic acid, acetic acid, formamide, N,N -dimethylformamide, acetonitrile, ethyl acetate, methyl ethyl ketone, acetone, dialkyl sulphoxide and tetrahydrofuran, and i) the water-insoluble sartan, ii) a water-soluble carrier material, which consists essentially of at least one surfactant and at least one polymer, iii) a solvent for each of the sartan and the carrier material, b) spray-drying the mixture to remove each solvent and to thereby obtain a substantially solvent-free nano-dispersion of the water-insoluble sartan in the carrier material, wherein the weight ratio of the sartan to carrier material is from 1:500 to 1:1.
An apparatus for discouraging a user from sucking on a digit of the user's hand, the apparatus comprising: a hollow vacuum-breaking device including a base and defining one or more air passages, the vacuum-breaking device being sized to permit insertion of the user's digit into the vacuum-breaking device so that the base of the vacuum-breaking device is nearer to the base of the digit than the tip thereof, the air passages of the vacuum-breaking device preventing the user from establishing a sucking vacuum when the respective digit including the vacuum-breaking device is inserted into the user's mouth; a pair of straps extending from the vacuum-breaking device, characterised in that the straps of the pair of straps defining respective pluralities of holes along their length, a pair of the holes including a hole of each of the pluralities being selectable according to a size of the user's hand, the straps being configured to cross when the holes of the pair of holes overlap; and a retainer configured to extend through overlapping holes of the straps to thereby secure the straps together, the retainer defining an aperture for receiving a wristband securable to the user's wrist to secure the straps to the user's wrist, the vacuum-breaking device thereby being securable to the user's hand. a hollow vacuum-breaking device including a base and defining one or more air passages, the vacuum-breaking device being sized to permit insertion of the user's digit into the vacuum-breaking device so that the base of the vacuum-breaking device is nearer to the base of the digit than the tip thereof, the air passages of the vacuum-breaking device preventing the user from establishing a sucking vacuum when the respective digit including the vacuum-breaking device is inserted into the user's mouth; a pair of straps extending from the vacuum-breaking device, characterised in that the straps of the pair of straps defining respective pluralities of holes along their length, a pair of the holes including a hole of each of the pluralities being selectable according to a size of the user's hand, the straps being configured to cross when the holes of the pair of holes overlap; and a retainer configured to extend through overlapping holes of the straps to thereby secure the straps together, the retainer defining an aperture for receiving a wristband securable to the user's wrist to secure the straps to the user's wrist, the vacuum-breaking device thereby being securable to the user's hand.
Method for post-processing a base component of a projectile, in particular of a guided missile, a warhead or a munition, comprising the steps of: providing a base component; and applying a reactive material having a material property which can be activated by means of a predetermined stimulus to a predetermined processing region of the base component in such a manner that the reactive material is bonded to the base component, characterised in that the reactive material comprises an intermetallic compound, wherein at least zirconium and tungsten are contained in the intermetallic compound. providing a base component; and applying a reactive material having a material property which can be activated by means of a predetermined stimulus to a predetermined processing region of the base component in such a manner that the reactive material is bonded to the base component, characterised in that the reactive material comprises an intermetallic compound, wherein at least zirconium and tungsten are contained in the intermetallic compound.
Glazing unit for fire protection wall elements, windows, doors and the like, having at least two parallel and spaced apart glass panes (2a, 2b) and a spacer arranged between these glass panes (2a, 2b), wherein the spacer has a sleeve and at least two contact faces (8a, 8b) which are parallel and spaced apart and securely connected to the sleeve, wherein a first contact face is intended to bear a first glass pane and a second contact face is intended to bear a second glass pane, and a spacing is defined by the contact faces (8a, 8b), wherein the spacer has the external shape of a reel, characterized in that the sleeve finishes flush on both sides with the contact faces (8a, 8b) and does not project beyond the contact faces (8a, 8b) and a compression sleeve, which projects beyond the outer faces of the glass panes (2a, 2b), is arranged in the sleeve, in particular in a form-fitting manner.