Dosing closure device for bottles, in particular for storing and dispensing liquid pharmaceuticals, having - a bottle neck of the bottle, - a multi-piece cap closure that is mountable on the bottle neck, comprising = an inner cap with a mounting element for attachment to the bottle neck, characterized by = an intermediate socket that is configured in one piece and detachably fastened to the inner cap, = an outer cap detachably fastened thereto with a mounting element for attachment to the bottle neck, as well as = a dosing insert held in the outer cap which, after the first opening of the cap closure, can be brought permanently into positional engagement in the outlet opening of the bottle neck by removing the inner cap and the intermediate socket and first placing the outer cap on the bottle neck, wherein the integrally formed intermediate socket has a cup-shaped, downwardly open base part and a sleeve-shaped, upwardly open retaining part, wherein the intermediate socket with the cup-shaped base part is slipped onto the inner cap and, for the detachable fastening of these two components to one another, a latching device is provided which is formed from a circumferential annular projection on the inside in front of the end-face edge of the base part and an annular shoulder that is cooperating therewith and circumferential on the outside of the inner cap, wherein the outer cap is detachably fastened to the retaining part and wherein the dosing insert is at least partially accommodated in the retaining part. - a bottle neck of the bottle, - a multi-piece cap closure that is mountable on the bottle neck, comprising = an inner cap with a mounting element for attachment to the bottle neck, characterized by = an intermediate socket that is configured in one piece and detachably fastened to the inner cap, = an outer cap detachably fastened thereto with a mounting element for attachment to the bottle neck, as well as = a dosing insert held in the outer cap which, after the first opening of the cap closure, can be brought permanently into positional engagement in the outlet opening of the bottle neck by removing the inner cap and the intermediate socket and first placing the outer cap on the bottle neck, wherein the integrally formed intermediate socket has a cup-shaped, downwardly open base part and a sleeve-shaped, upwardly open retaining part, wherein the intermediate socket with the cup-shaped base part is slipped onto the inner cap and, for the detachable fastening of these two components to one another, a latching device is provided which is formed from a circumferential annular projection on the inside in front of the end-face edge of the base part and an annular shoulder that is cooperating therewith and circumferential on the outside of the inner cap, wherein the outer cap is detachably fastened to the retaining part and wherein the dosing insert is at least partially accommodated in the retaining part. = an inner cap with a mounting element for attachment to the bottle neck, characterized by = an intermediate socket that is configured in one piece and detachably fastened to the inner cap, = an outer cap detachably fastened thereto with a mounting element for attachment to the bottle neck, as well as = a dosing insert held in the outer cap which, after the first opening of the cap closure, can be brought permanently into positional engagement in the outlet opening of the bottle neck by removing the inner cap and the intermediate socket and first placing the outer cap on the bottle neck, wherein the integrally formed intermediate socket has a cup-shaped, downwardly open base part and a sleeve-shaped, upwardly open retaining part, wherein the intermediate socket with the cup-shaped base part is slipped onto the inner cap and, for the detachable fastening of these two components to one another, a latching device is provided which is formed from a circumferential annular projection on the inside in front of the end-face edge of the base part and an annular shoulder that is cooperating therewith and circumferential on the outside of the inner cap, wherein the outer cap is detachably fastened to the retaining part and wherein the dosing insert is at least partially accommodated in the retaining part.