mhurhangee/ep-ind-claims huggingface dataset:
A process for obtaining a precursor molecule of insulin or insulin analog having correctly bonded cysteine bridges, which comprises: (a) providing a suspension of inclusion bodies obtained from E. coli host cells, wherein the inclusion bodies comprise precursor molecules of insulin or insulin analog having incorrectly bonded cysteine bridges; (b) solubilizing the inclusion bodies by adding urea, dithiothreitol, and ethanolamine to the suspension to provide a solubilization solution, wherein the solubilization solution comprises about 12 to 18 g/L of the precursor molecules of insulin or insulin analog having incorrectly bonded cysteine bridges, about 3.8 to 4.3 M urea, about 2.2 to 2.8 mM DTT, and about 265 to 365 mM ethanolamine, and has a pH of about 10.5; (c) diluting the solubilization solution about 10-fold with a refold diluent solution comprising ethanolamine and cystamine to provide a refold solution having about 1.2 to 1.8 g/L of the precursor molecules of insulin or insulin analog having incorrectly bonded cysteine bridges, 0.38 to 0.43 M urea, 345 to 404 μM cystamine, about 0.22 to 0.28 mM DTT, and about 40 mM ethanolamine and has a pH of about 10.5; and (d) incubating the refold solution with stirring to provide aeration for 6 to 12 hours to provide the precursor of insulin or insulin analog having correctly bonded cysteine bridges. (a) providing a suspension of inclusion bodies obtained from E. coli host cells, wherein the inclusion bodies comprise precursor molecules of insulin or insulin analog having incorrectly bonded cysteine bridges; (b) solubilizing the inclusion bodies by adding urea, dithiothreitol, and ethanolamine to the suspension to provide a solubilization solution, wherein the solubilization solution comprises about 12 to 18 g/L of the precursor molecules of insulin or insulin analog having incorrectly bonded cysteine bridges, about 3.8 to 4.3 M urea, about 2.2 to 2.8 mM DTT, and about 265 to 365 mM ethanolamine, and has a pH of about 10.5; (c) diluting the solubilization solution about 10-fold with a refold diluent solution comprising ethanolamine and cystamine to provide a refold solution having about 1.2 to 1.8 g/L of the precursor molecules of insulin or insulin analog having incorrectly bonded cysteine bridges, 0.38 to 0.43 M urea, 345 to 404 μM cystamine, about 0.22 to 0.28 mM DTT, and about 40 mM ethanolamine and has a pH of about 10.5; and (d) incubating the refold solution with stirring to provide aeration for 6 to 12 hours to provide the precursor of insulin or insulin analog having correctly bonded cysteine bridges.
An apparatus, comprising: control circuitry configured to cause a base station (150, 550, 650) configured for machine-type communication, MTC, to: determine a super-frame structure, the super-frame structure comprising a control region in a super-frame according to the super-frame structure, and a number of subframes in a data region of the super-frame, wherein the number of subframes in the data region of the super-frame is set, at least in part, based on a coverage enhancement target of a narrowband deployment; determine configuration information for a user equipment, UE, in communication with the base station (150, 550, 650); and generate a configuration for an MTC control format indicator, M-CFI, for the UE (101, 501, 601) to indicate the determined configuration information; and transmit circuitry configured to transmit the M-CFI through a narrowband MTC Physical Control Format Indicator Channel, M-PCFICH, (360, 460) within the control region of the super-frame, wherein the M-PCFICH (360, 460) carries the M-CFI, which is used to indicate information for MTC Physical Downlink Control Channel, M-PDCCH, WEPBEEH and MTC Physical Downlink Shared Channel, M-PDSCH, transmission. determine a super-frame structure, the super-frame structure comprising a control region in a super-frame according to the super-frame structure, and a number of subframes in a data region of the super-frame, wherein the number of subframes in the data region of the super-frame is set, at least in part, based on a coverage enhancement target of a narrowband deployment; determine configuration information for a user equipment, UE, in communication with the base station (150, 550, 650); and generate a configuration for an MTC control format indicator, M-CFI, for the UE (101, 501, 601) to indicate the determined configuration information; and transmit circuitry configured to transmit the M-CFI through a narrowband MTC Physical Control Format Indicator Channel, M-PCFICH, (360, 460) within the control region of the super-frame, wherein the M-PCFICH (360, 460) carries the M-CFI, which is used to indicate information for MTC Physical Downlink Control Channel, M-PDCCH, WEPBEEH and MTC Physical Downlink Shared Channel, M-PDSCH, transmission.
A terminal-equipped electric wire comprising: an electric wire that comprises: a conductor formed of at least one element wire, and a covering that covers an outer periphery of the conductor; and a compression terminal fixed to an end of the conductor, wherein the at least one element wire is made of a first material comprising aluminum as a main component, wherein at least a part, which contacts the conductor, of the compression terminal is made of a second material comprising aluminum as a main component, wherein the second material is pure aluminum that consists of Al and inevitable impurities, wherein the first material has a tensile strength greater than a tensile strength of the second material, characterised in that the first material is an aluminum alloy that comprises: 0.2 to 1.0% by mass of Fe; 0.01 to 0.10% by mass of Zr; 0.1% by mass or less of Si; 0.01% by mass or less of Cu; 0.01% by mass or less of Mn; 0.01% by mass or less of Mg; 0.01% by mass or less of Zn; 0.01% by mass or less of Ti; 0.01% by mass or less of V; and a remainder comprising Al and inevitable impurities, and wherein the terminal is provided with multiple compressed points along a longitudinal direction of the conductor. an electric wire that comprises: a conductor formed of at least one element wire, and a covering that covers an outer periphery of the conductor; and a compression terminal fixed to an end of the conductor, wherein the at least one element wire is made of a first material comprising aluminum as a main component, a conductor formed of at least one element wire, and a covering that covers an outer periphery of the conductor; and a compression terminal fixed to an end of the conductor, wherein the at least one element wire is made of a first material comprising aluminum as a main component, wherein at least a part, which contacts the conductor, of the compression terminal is made of a second material comprising aluminum as a main component, wherein the second material is pure aluminum that consists of Al and inevitable impurities, wherein the first material has a tensile strength greater than a tensile strength of the second material, characterised in that the first material is an aluminum alloy that comprises: 0.2 to 1.0% by mass of Fe; 0.01 to 0.10% by mass of Zr; 0.1% by mass or less of Si; 0.01% by mass or less of Cu; 0.01% by mass or less of Mn; 0.01% by mass or less of Mg; 0.01% by mass or less of Zn; 0.01% by mass or less of Ti; 0.01% by mass or less of V; and 0.2 to 1.0% by mass of Fe; 0.01 to 0.10% by mass of Zr; 0.1% by mass or less of Si; 0.01% by mass or less of Cu; 0.01% by mass or less of Mn; 0.01% by mass or less of Mg; 0.01% by mass or less of Zn; 0.01% by mass or less of Ti; 0.01% by mass or less of V; and
A method for queueing packets in a queueing system at a network element in a packet-switched network (300A, 300B), wherein each packet of said packets is sent from a source in said packet-switched network to a destination in said packet-switched network via said network element, wherein each packet of said packets comprises timing information representing a remaining time until a deadline associated with delivery of said packet at its destination; characterized in that said queueing system comprises: - a plurality of N queues, wherein each queue of said plurality of N queues is configured for buffering at least one packet of said packets, and wherein said plurality of N queues has a cyclic order; and in that said method comprises: - keeping track of a pointer, wherein at a first point in time said pointer points to a queue of said plurality of N queues; - after a second point in time succeeding said first point in time, repeatedly incrementing said pointer over said plurality of N queues, according to said cyclic order of said plurality of N queues, after each passing of a scheduling interval S, wherein said scheduling interval S represents an amount of time; - enqueueing each packet of said packets in a queue of said plurality of N queues, wherein that queue differs from the queue of said plurality of N queues to which said pointer is pointing, based on said packet's timing information and taking into account said cyclic order of said plurality of N queues; and - dequeueing enqueued packets from said plurality of N queues, while prioritizing dequeueing from the queue of said plurality of N queues to which said pointer is pointing. - a plurality of N queues, wherein each queue of said plurality of N queues is configured for buffering at least one packet of said packets, and wherein said plurality of N queues has a cyclic order; - keeping track of a pointer, wherein at a first point in time said pointer points to a queue of said plurality of N queues; - after a second point in time succeeding said first point in time, repeatedly incrementing said pointer over said plurality of N queues, according to said cyclic order of said plurality of N queues, after each passing of a scheduling interval S, wherein said scheduling interval S represents an amount of time; - enqueueing each packet of said packets in a queue of said plurality of N queues, wherein that queue differs from the queue of said plurality of N queues to which said pointer is pointing, based on said packet's timing information and taking into account said cyclic order of said plurality of N queues; and - dequeueing enqueued packets from said plurality of N queues, while prioritizing dequeueing from the queue of said plurality of N queues to which said pointer is pointing.
A method for implementing trusted computing, the method comprising: executing, by a central processing unit, CPU (330, 430),each respective software component in a sequence of software components (320, 420), stored on a storage device (310, 410) at a location from where the CPU (330, 430) is configured to load a first instruction at a boot process,; measuring, by each respective software component, a next software component in the sequence, and providing the resulting measurement to a security module (340, 440) connected to the CPU (330, 430); characterized in that said storage device (310, 410) is write-protected, wherein the method further comprises authorizing, by the security module (340, 440), an update of one or more software components in the sequence of software components (320, 420) based on the provided resulting measurements; and upon successful authorization by the security module (340, 440) changing, by the CPU (330, 430), the status of the storage device (310, 410) to be write-enabled so as to perform the update of one or more software components. executing, by a central processing unit, CPU (330, 430),each respective software component in a sequence of software components (320, 420), stored on a storage device (310, 410) at a location from where the CPU (330, 430) is configured to load a first instruction at a boot process,; measuring, by each respective software component, a next software component in the sequence, and providing the resulting measurement to a security module (340, 440) connected to the CPU (330, 430); characterized in that said storage device (310, 410) is write-protected, wherein the method further comprises authorizing, by the security module (340, 440), an update of one or more software components in the sequence of software components (320, 420) based on the provided resulting measurements; and upon successful authorization by the security module (340, 440) changing, by the CPU (330, 430), the status of the storage device (310, 410) to be write-enabled so as to perform the update of one or more software components.
Prefabricated building element (1; 101) including a concrete body and at least one thermal insulation main unit (5; 105) secured to the concrete body, the main unit being arranged to protrude from an upper face of the concrete body, the element being characterized in that it includes at least one thermal insulation and structural support secondary unit (8; 108) comprising a block of specific concrete having a thermal conductivity less than 1 watt per metre kelvin and reinforcements arranged in said block, the block and the main unit extending side by side so that said unit is anchored in said specific concrete block, the secondary unit (8; 108) being arranged so as to protrude from the upper face of the concrete body.
An imaging apparatus to which a lens apparatus is detachably attached, comprising: imaging means configured to generate an image signal by photoelectrically converting an object image; first acquisition means (227; 230) configured to acquire a contrast value based on the image signal obtained by the imaging means; second acquisition means configured to acquire lens position information at a predetermined time interval; and focus detection means configured to detect a focal position based on outputs of the first acquisition means and the second acquisition means; wherein a length of a charge accumulation period in a frame of image signal generation is changeable, characterized in that the first acquisition means (227; 230) is configured to obtain first timing information corresponding to a timing of each charge accumulation period based on which the contrast value is acquired, and the second acquisition means is configured to obtain second timing information corresponding to a timing at which each piece of the lens position information is acquired, and the focus detection means is configured to relate the lens position information from a plurality of pieces of the lens position information acquired by the second acquisition means with the contrast value acquired by the first acquisition means (227; 230), to detect the focal position, based on a timing between the first timing information and the second timing information. imaging means configured to generate an image signal by photoelectrically converting an object image; first acquisition means (227; 230) configured to acquire a contrast value based on the image signal obtained by the imaging means; second acquisition means configured to acquire lens position information at a predetermined time interval; and focus detection means configured to detect a focal position based on outputs of the first acquisition means and the second acquisition means; wherein a length of a charge accumulation period in a frame of image signal generation is changeable, characterized in that the first acquisition means (227; 230) is configured to obtain first timing information corresponding to a timing of each charge accumulation period based on which the contrast value is acquired, and the second acquisition means is configured to obtain second timing information corresponding to a timing at which each piece of the lens position information is acquired, and the focus detection means is configured to relate the lens position information from a plurality of pieces of the lens position information acquired by the second acquisition means with the contrast value acquired by the first acquisition means (227; 230), to detect the focal position, based on a timing between the first timing information and the second timing information.
Method for segmenting the data from a 3-D sensor, generated in the presence of aerosol clouds, in order to increase the situational awareness and the detection of the position of obstacles, wherein - in a first step, the sensor data are transformed into a 3-D measurement point cloud, - in a second step, contiguous subsets, so-called measurement point clusters, are determined from the 3-D measurement point cloud of an individual measuring cycle of the 3-D sensor on the basis of the local measurement point density, - in a third step, at least one of the following characteristic variables of the individual measurement point clusters are determined: - position, - orientation in space, - shape, - in a fourth step, the temporal change in these characteristic variables is determined on the basis of the sensor data recorded in subsequent measuring cycles, which change reveals the affiliation of a measurement point cluster to a real obstacle or to the aerosol cloud. - in a first step, the sensor data are transformed into a 3-D measurement point cloud, - in a second step, contiguous subsets, so-called measurement point clusters, are determined from the 3-D measurement point cloud of an individual measuring cycle of the 3-D sensor on the basis of the local measurement point density, - in a third step, at least one of the following characteristic variables of the individual measurement point clusters are determined: - position, - orientation in space, - shape, - position, - orientation in space, - shape, - in a fourth step, the temporal change in these characteristic variables is determined on the basis of the sensor data recorded in subsequent measuring cycles, which change reveals the affiliation of a measurement point cluster to a real obstacle or to the aerosol cloud.
A medical signal processing device configured to receive a RAW signal imaged by a medical observation device and processes the RAW signal, comprising: a signal input unit configured to receive the RAW signal; a first signal converting unit (62, 62C) configured to convert the RAW signal received by the signal input unit from an RGB signal into a luminance signal and a color difference signal by performing a matrix calculating process; an identification information appending unit (63, 63C) configured to append color gamut identification information related to a color gamut of the picture signal and identifying the matrix calculating process used by the first converting unit (62, 62C), to a picture signal resulting from the conversion; and a signal output unit (64, 64C) configured to output the picture signal to which the color gamut identification information has been appended, to either an external medical display device or an external medical recording device. a signal input unit configured to receive the RAW signal; a first signal converting unit (62, 62C) configured to convert the RAW signal received by the signal input unit from an RGB signal into a luminance signal and a color difference signal by performing a matrix calculating process; an identification information appending unit (63, 63C) configured to append color gamut identification information related to a color gamut of the picture signal and identifying the matrix calculating process used by the first converting unit (62, 62C), to a picture signal resulting from the conversion; and a signal output unit (64, 64C) configured to output the picture signal to which the color gamut identification information has been appended, to either an external medical display device or an external medical recording device.
Y-connector for medical lines, comprising a tubular body having a first inlet coaxial with the tubular body and containing a valve device formed by a hollow elastic element sealingly closing said first inlet in an openable manner, an outlet, and a second inlet arranged obliquely to the tubular body and communicating therewith between said first inlet and the outlet, said tubular body is formed with an inner septum for deviating the flow coming from the second inlet towards said elastic element prior to directing it to the outlet, said inner septum extending axially and being provided with a radial end portion connected to the tubular body in proximity of said second inlet so as to define a first chamber open towards the elastic element and closed on the side of the outlet, and a second chamber open towards the elastic element and towards the outlet characterised in that said inner septum is offset relative to the axis of the tubular body such that the first chamber has a radial size greater than that of the second chamber.
A module for treatment of a fluid comprising: an inner pressure vessel designed to accommodate a treatment medium, the treatment medium being selected to remove radioactive contaminants from a fluid passed through the pressure vessel; an outer shield vessel surrounding the pressure vessel and designed to attenuate the radiation from the radioactive contaminants accumulated by the treatment medium in the pressure vessel and to facilitate ease of handling and storage of the module together with the contaminated treatment medium; and an annular region between the pressure vessel and the shield vessel for passing a cooling medium therethrough to remove decay heat from the radioactive contaminants accumulated in the pressure vessel, characterised in that the treatment medium selected to remove radioactive contaminants from the contaminated fluid is an ion exchange medium. an inner pressure vessel designed to accommodate a treatment medium, the treatment medium being selected to remove radioactive contaminants from a fluid passed through the pressure vessel; an outer shield vessel surrounding the pressure vessel and designed to attenuate the radiation from the radioactive contaminants accumulated by the treatment medium in the pressure vessel and to facilitate ease of handling and storage of the module together with the contaminated treatment medium; and an annular region between the pressure vessel and the shield vessel for passing a cooling medium therethrough to remove decay heat from the radioactive contaminants accumulated in the pressure vessel, characterised in that the treatment medium selected to remove radioactive contaminants from the contaminated fluid is an ion exchange medium.
An adhesive-backed polymeric film assembly comprising: a polymeric film comprising a polyurethane polymeric material and having a back surface and a front surface; and a release liner having an outer surface and an inner surface releasably bonded to said adhesive, wherein said assembly is wound into a roll, with the outer surface of said release liner facing outwardly and the front surface of said polymeric film facing inwardly, and wherein said polymeric film comprises multiple discrete films, with the adhesive on the back surface of each said discrete films being releasably bonded to the inner surface of said release liner, each said discrete film having a surface area with a desired 2-dimensional shape and a peripheral edge that defines the 2-dimensional shape of said surface area designed to cover a corresponding area of a substrate. a polymeric film comprising a polyurethane polymeric material and having a back surface and a front surface; and a release liner having an outer surface and an inner surface releasably bonded to said adhesive, wherein said assembly is wound into a roll, with the outer surface of said release liner facing outwardly and the front surface of said polymeric film facing inwardly, and wherein said polymeric film comprises multiple discrete films, with the adhesive on the back surface of each said discrete films being releasably bonded to the inner surface of said release liner, each said discrete film having a surface area with a desired 2-dimensional shape and a peripheral edge that defines the 2-dimensional shape of said surface area designed to cover a corresponding area of a substrate.