A radially collapsible and balloon-expandable frame for a prosthetic valve, wherein the frame, when viewed in a flattened state thereof, comprises a plurality of struts, the struts extending longitudinally, being sinusoidal-shaped or undulating, and connecting to each other at nodes so as to define a plurality of open cells arranged in plural rows along the longitudinal flow axis of the frame; wherein the plural rows consist of one inflow row of cells, one outflow row of cells, and one or two intermediate rows of cells between the inflow and outflow rows of cells; wherein the outflow row includes six cells, and the inflow row and each intermediate row include twelve cells each, wherein three circumferentially spaced, longitudinally extending commissure attachment posts are interspaced between a plurality of frame apices, and wherein the frame is suitable for being balloon-expanded in a shape defined by: an inflow end portion of the frame increasing in diameter from a diameter D1 at an inflow end of the frame to a relatively larger diameter D2 at a distance spaced from the inflow end of the frame, an intermediate portion defining a landing zone for positioning the intermediate portion within the native annulus when the prosthetic valve is deployed, the intermediate portion initially decreasing in diameter from the diameter D2 to a relatively smaller diameter D3 at a middle section of the intermediate portion and then increasing in diameter to a diameter D4 proximate an outflow end of the frame, an outflow portion of the frame decreasing in diameter from the diameter D4 at an outflow end of the intermediate portion to a diameter D5 at the outflow end of the frame, the diameter D5 being defined by upper free ends of the commissure attachment posts, and the commissure attachment posts extending inwardly at an angle of about 10 degrees to about 60 degrees with respect the flow axis A. wherein the plural rows consist of one inflow row of cells, one outflow row of cells, and one or two intermediate rows of cells between the inflow and outflow rows of cells; wherein the outflow row includes six cells, and the inflow row and each intermediate row include twelve cells each, wherein three circumferentially spaced, longitudinally extending commissure attachment posts are interspaced between a plurality of frame apices, and wherein the frame is suitable for being balloon-expanded in a shape defined by: an inflow end portion of the frame increasing in diameter from a diameter D1 at an inflow end of the frame to a relatively larger diameter D2 at a distance spaced from the inflow end of the frame, an intermediate portion defining a landing zone for positioning the intermediate portion within the native annulus when the prosthetic valve is deployed, the intermediate portion initially decreasing in diameter from the diameter D2 to a relatively smaller diameter D3 at a middle section of the intermediate portion and then increasing in diameter to a diameter D4 proximate an outflow end of the frame, an inflow end portion of the frame increasing in diameter from a diameter D1 at an inflow end of the frame to a relatively larger diameter D2 at a distance spaced from the inflow end of the frame, an intermediate portion defining a landing zone for positioning the intermediate portion within the native annulus when the prosthetic valve is deployed, the intermediate portion initially decreasing in diameter from the diameter D2 to a relatively smaller diameter D3 at a middle section of the intermediate portion and then increasing in diameter to a diameter D4 proximate an outflow end of the frame, an outflow portion of the frame decreasing in diameter from the diameter D4 at an outflow end of the intermediate portion to a diameter D5 at the outflow end of the frame, the diameter D5 being defined by upper free ends of the commissure attachment posts, and the commissure attachment posts extending inwardly at an angle of about 10 degrees to about 60 degrees with respect the flow axis A.