A heat exchange catheter, comprising: a supply conduit configured to supply working fluid received from a source to a distal location; a return conduit communicating with the supply conduit at the distal location and configured to communicate with the source; wherein: the catheter defines a longitudinal axis, and portions of the supply conduit establish axially longer segments and axially shorter segments and portions of the return conduit establish axially longer segments and axially shorter segments, the axially shorter segments (114, 118) being shorter in the dimension defined by the longitudinal axis than the axially longer segments (112, 116), and further wherein at least one of the axially shorter segments (118, 136) of the return conduit is bordered by and extends axially between first and second transverse legs of a corresponding one of the axially longer segments of the supply conduit, the at least one axially shorter segment (118, 136) of the return conduit extending from a first transverse segment of the return conduit to a second transverse segment of the return conduit, at least one of the axially shorter segments of the supply conduit is bordered by and extends axially between first and second transverse legs of a corresponding one of the axially longer segments of the return conduit, the at least one axially shorter segment of the supply conduit extending from a first transverse segment of the supply conduit to a second transverse segment of the supply conduit, at least the axially shorter segments being oriented parallel to the longitudinal axis. a supply conduit configured to supply working fluid received from a source to a distal location; a return conduit communicating with the supply conduit at the distal location and configured to communicate with the source; wherein: the catheter defines a longitudinal axis, and portions of the supply conduit establish axially longer segments and axially shorter segments and portions of the return conduit establish axially longer segments and axially shorter segments, the axially shorter segments (114, 118) being shorter in the dimension defined by the longitudinal axis than the axially longer segments (112, 116), and further wherein at least one of the axially shorter segments (118, 136) of the return conduit is bordered by and extends axially between first and second transverse legs of a corresponding one of the axially longer segments of the supply conduit, the at least one axially shorter segment (118, 136) of the return conduit extending from a first transverse segment of the return conduit to a second transverse segment of the return conduit, at least one of the axially shorter segments of the supply conduit is bordered by and extends axially between first and second transverse legs of a corresponding one of the axially longer segments of the return conduit, the at least one axially shorter segment of the supply conduit extending from a first transverse segment of the supply conduit to a second transverse segment of the supply conduit, at least the axially shorter segments being oriented parallel to the longitudinal axis. the catheter defines a longitudinal axis, and portions of the supply conduit establish axially longer segments and axially shorter segments and portions of the return conduit establish axially longer segments and axially shorter segments, the axially shorter segments (114, 118) being shorter in the dimension defined by the longitudinal axis than the axially longer segments (112, 116), and further wherein at least one of the axially shorter segments (118, 136) of the return conduit is bordered by and extends axially between first and second transverse legs of a corresponding one of the axially longer segments of the supply conduit, the at least one axially shorter segment (118, 136) of the return conduit extending from a first transverse segment of the return conduit to a second transverse segment of the return conduit, at least one of the axially shorter segments of the supply conduit is bordered by and extends axially between first and second transverse legs of a corresponding one of the axially longer segments of the return conduit, the at least one axially shorter segment of the supply conduit extending from a first transverse segment of the supply conduit to a second transverse segment of the supply conduit, at least the axially shorter segments being oriented parallel to the longitudinal axis.