A pressure detection device, comprising a sensor unit and a sensor unit accommodating portion configured to accommodate the sensor unit, the sensor unit comprising a sensor chip configured to detect a pressure, a chip mounting member having an outer peripheral surface and supporting the sensor chip at one end portion of the chip mounting member, a cylindrical housing having an inner peripheral portion with an inner peripheral surface and configured to accommodate a hermetic glass surrounding at least one terminal electrically connected to a circuit in the sensor chip between the outer peripheral surface of the chip mounting member and the inner peripheral surface of the housing, a diaphragm supported with a peripheral edge of the diaphragm at a lower end surface of the housing and configured to isolate the inner peripheral portion of the housing from a pressure chamber of which a pressure is to be detected, such that a liquid seal chamber is formed between the diaphragm and a lower end surface of the hermetic glass and the sensor chip is accommodated in the liquid seal chamber, a pressure transfer medium filled into the liquid seal chamber, an electrostatic protection layer (50, 54), and a terminal block having a lower side, a cavity located on an inner side at the lower side and a lower end surface attached to an upper end surface (12ES1) of the housing such that an upper end surface of the (14ES1) of the hermetic glass is covered by the terminal block and configured to align the terminal(s) of the sensor unit, characterized in that the electrostatic protection layer (50, 54) is formed either only at a portion, which is surrounded by and in direct contact with the lower end surface of the terminal block, the inner peripheral surface of the housing, and an outer peripheral edge portion of the upper end surface of the hermetic glass, or only from an annular projection of the terminal block, the annular projection being formed on a lower surface of the terminal block forming the cavity and opposed to the upper end surface (14ES1) of the hermetic glass and protruding toward the upper end surface of the hermetic glass with a gap between the annular projection and an inner peripheral surface of the terminal block forming the cavity substantially orthogonal to the upper end surface (14ES1) of the hermetic glass, to the upper end surface (14ES1) of the hermetic glass. a sensor unit and a sensor unit accommodating portion configured to accommodate the sensor unit, the sensor unit comprising a sensor chip configured to detect a pressure, a chip mounting member having an outer peripheral surface and supporting the sensor chip at one end portion of the chip mounting member, a cylindrical housing having an inner peripheral portion with an inner peripheral surface and configured to accommodate a hermetic glass surrounding at least one terminal electrically connected to a circuit in the sensor chip between the outer peripheral surface of the chip mounting member and the inner peripheral surface of the housing, a diaphragm supported with a peripheral edge of the diaphragm at a lower end surface of the housing and configured to isolate the inner peripheral portion of the housing from a pressure chamber of which a pressure is to be detected, such that a liquid seal chamber is formed between the diaphragm and a lower end surface of the hermetic glass and the sensor chip is accommodated in the liquid seal chamber, a pressure transfer medium filled into the liquid seal chamber, an electrostatic protection layer (50, 54), and a terminal block having a lower side, a cavity located on an inner side at the lower side and a lower end surface attached to an upper end surface (12ES1) of the housing such that an upper end surface of the (14ES1) of the hermetic glass is covered by the terminal block and configured to align the terminal(s) of the sensor unit, characterized in that the electrostatic protection layer (50, 54) is formed either only at a portion, which is surrounded by and in direct contact with the lower end surface of the terminal block, the inner peripheral surface of the housing, and an outer peripheral edge portion of the upper end surface of the hermetic glass, or only from an annular projection of the terminal block, the annular projection being formed on a lower surface of the terminal block forming the cavity and opposed to the upper end surface (14ES1) of the hermetic glass and protruding toward the upper end surface of the hermetic glass with a gap between the annular projection and an inner peripheral surface of the terminal block forming the cavity substantially orthogonal to the upper end surface (14ES1) of the hermetic glass, to the upper end surface (14ES1) of the hermetic glass.