A compound of the general formula wherein R is -H, or -C 1 -C 4 -alkyl, preferably -H, -methyl or -ethyl; in particular methyl; R 1 is -H, or -methyl, preferably -H; M is CH or N; preferably CH; V is -H, -OH, -Cl, -F, or -C 1 -C 4 -alkyl, preferably -H, -Cl, -F, or -methyl; W is R 2 and R 3 are identical or different and are -H, -C 1 -C 4 -alkyl, halogen-C 1 -C 4 -alkyl, -C 1 -C 4 -alkoxy, -C 1 -C 4 -dialkylamino, -C 2 -C 6 -alkenyl, -C 2 -C 6 -alkynyl, -halogen, -CN or -CO-NH 2; preferably-H, -C 1 -C 4 -alkyl, -CF 3, -OCH 3, -NHCH 3, -N(CH 3) 2, -F, or -Cl; X is -halogen, or -CN, preferably -F, with n = 1 or 2 or with m = 1; n = 0, 1, or 2, preferably 0 or 1; m = 0 or 1, preferably 0; Y is -NR 4 R 5 with R 4 is -H, or -C 1 -C 4 -alkyl, preferably -H or -methyl, and R 5 is -H, -C 1 -C 4 -alkyl, an unsubstituted or substituted -C 3 -C 6 -cycloalkyl, preferably -methyl, -ethyl, -isopropyl, or -cyclopropyl; or an unsubstituted or substituted pyridine residue; or an unsubstituted or substituted phenyl residue, preferably substituted at the para position; or Y is -NR 4 R 5 with N, R 4 and R 5 forming an unsubstituted or substituted 4-, 5- or 6-membered saturated heterocycle, preferably an unsubstituted or substituted azetidine residue, an unsubstituted or substituted piperidine residue, an unsubstituted or substituted pyrrolidine residue, an unsubstituted or substituted piperazine residue, an unsubstituted or substituted morpholine residue, or an unsubstituted or substituted tetrahydropyridine residue; or Y is -OR 6, with R 6 is -H or -C 1 -C 4 -alkyl, preferably -H, -methyl, -ethyl, -isopropyl, or -tert -butyl; or a pharmaceutically or veterinary acceptable salt, hydrate or solvate thereof. R is -H, or -C 1 -C 4 -alkyl, preferably -H, -methyl or -ethyl; in particular methyl; R 1 is -H, or -methyl, preferably -H; M is CH or N; preferably CH; V is -H, -OH, -Cl, -F, or -C 1 -C 4 -alkyl, preferably -H, -Cl, -F, or -methyl; W is R 2 and R 3 are identical or different and are -H, -C 1 -C 4 -alkyl, halogen-C 1 -C 4 -alkyl, -C 1 -C 4 -alkoxy, -C 1 -C 4 -dialkylamino, -C 2 -C 6 -alkenyl, -C 2 -C 6 -alkynyl, -halogen, -CN or -CO-NH 2; preferably-H, -C 1 -C 4 -alkyl, -CF 3, -OCH 3, -NHCH 3, -N(CH 3) 2, -F, or -Cl; X is -halogen, or -CN, preferably -F, with n = 1 or 2 or with m = 1; n = 0, 1, or 2, preferably 0 or 1; m = 0 or 1, preferably 0; R 2 and R 3 are identical or different and are -H, -C 1 -C 4 -alkyl, halogen-C 1 -C 4 -alkyl, -C 1 -C 4 -alkoxy, -C 1 -C 4 -dialkylamino, -C 2 -C 6 -alkenyl, -C 2 -C 6 -alkynyl, -halogen, -CN or -CO-NH 2; preferably-H, -C 1 -C 4 -alkyl, -CF 3, -OCH 3, -NHCH 3, -N(CH 3) 2, -F, or -Cl; -H, -C 1 -C 4 -alkyl, halogen-C 1 -C 4 -alkyl, -C 1 -C 4 -alkoxy, -C 1 -C 4 -dialkylamino, -C 2 -C 6 -alkenyl, -C 2 -C 6 -alkynyl, -halogen, -CN or -CO-NH 2; preferably-H, -C 1 -C 4 -alkyl, -CF 3, -OCH 3, -NHCH 3, -N(CH 3) 2, -F, or -Cl; X is -halogen, or -CN, preferably -F, with n = 1 or 2 or with m = 1; n = 0, 1, or 2, preferably 0 or 1; m = 0 or 1, preferably 0; Y is -NR 4 R 5 with R 4 is -H, or -C 1 -C 4 -alkyl, preferably -H or -methyl, and R 5 is -H, -C 1 -C 4 -alkyl, an unsubstituted or substituted -C 3 -C 6 -cycloalkyl, preferably -methyl, -ethyl, -isopropyl, or -cyclopropyl; or an unsubstituted or substituted pyridine residue; or an unsubstituted or substituted phenyl residue, preferably substituted at the para position; or R 4 is -H, or -C 1 -C 4 -alkyl, preferably -H or -methyl, and R 5 is -H, -C 1 -C 4 -alkyl, an unsubstituted or substituted -C 3 -C 6 -cycloalkyl, preferably -methyl, -ethyl, -isopropyl, or -cyclopropyl; or an unsubstituted or substituted pyridine residue; or an unsubstituted or substituted phenyl residue, preferably substituted at the para position; or an unsubstituted or substituted pyridine residue; or an unsubstituted or substituted phenyl residue, preferably substituted at the para position; or Y is -NR 4 R 5 with N, R 4 and R 5 forming an unsubstituted or substituted 4-, 5- or 6-membered saturated heterocycle, preferably an unsubstituted or substituted azetidine residue, an unsubstituted or substituted piperidine residue, an unsubstituted or substituted pyrrolidine residue, an unsubstituted or substituted piperazine residue, an unsubstituted or substituted morpholine residue, or an unsubstituted or substituted tetrahydropyridine residue; or Y is -OR 6, with R 6 is -H or -C 1 -C 4 -alkyl, preferably -H, -methyl, -ethyl, -isopropyl, or -tert -butyl;