Compound of general formula: wherein X is O or NH; U-V are selected from the following groups: R 1 is a group of formula -CH 2 Ar wherein Ar is an optionally substitured aryl or heteroaryl group; R 4 and R 8 together are a group of formula -(CH 2) n - wherein this group may optionally be substituted and n is 2, 3, 4 or 5; R 5, R 6 and R 7 are independently hydrogen or C 1-4 alkyl; R 9 is a hydrogen atom, an alkyl, an alkenyl, an alkynyl, a heteroalkyl, a cycloalkyl, a heterocycloalkyl, an alkylcycloalkyl, a heteroalkylcycloalkyl, an aryl, a heteroaryl, an aralkyl or a heteroaralkyl group; and R 10 is H or methyl; or a pharmacologically acceptable salt, solvate, or hydrate thereof; wherein the expression alkyl refers to a saturated, straight-chain or branched hydrocarbon group that contains from 1 to 6 carbon atoms; the expressions alkenyl and alkynyl refer to at least partially unsaturated, straight-chain or branched hydrocarbon groups that contain from 2 to 6 carbon atoms; the expression heteroalkyl refers to an alkyl, alkenyl or alkynyl group in which one or more carbon atoms have been replaced by an oxygen, nitrogen or sulphur atom; the terms alkyl, alkenyl, alkynyl and heteroalkyl refer furthermore to groups in which one or more hydrogen atoms have been replaced by a halogen atom; the expression cycloalkyl refers to a saturated or partially unsaturated, cyclic group that contains one or two rings, containing from 3 to 10 carbon atoms; the expression cycloalkyl refers furthermore to groups in which one or more hydrogen atoms have been replaced by fluorine, chlorine, bromine or iodine atoms or by OH, =O, SH, =S, NH 2, =NH or NO 2 groups; the expression heterocycloalkyl refers to a cycloalkyl group as defined above in which one or more ring carbon atoms have been replaced by an oxygen, nitrogen or sulphur atom; the expression alkylcycloalkyl refers to groups containing both cycloalkyl and also alkyl, alkenyl or alkynyl groups in accordance with the above definitions; the expression heteroalkylcycloalkyl refers to alkylcycloalkyl groups as defined above in which one or more carbon atoms have been replaced by an oxygen, nitrogen or sulphur atom; the expression aryl refers to an aromatic group that has one or more rings containing from 6 to 10 carbon atoms; the expression aryl refers furthermore to groups in which one or more hydrogen atoms have been replaced by fluorine, chlorine, bromine or iodine atoms or by OH, SH, NH 2 or NO 2 groups; the expression heteroaryl refers to an aromatic group that has one or more rings containing from 5 to 10 ring atoms, and contains one or more oxygen, nitrogen or sulphur ring atoms; the expression heteroaryl refers furthermore to groups in which one or more hydrogen atoms have been replaced by fluorine, chlorine, bromine or iodine atoms or by OH, SH, NH 2 or NO 2 groups; the expression aralkyl refers to groups containing both aryl and also alkyl, alkenyl, alkynyl and/or cycloalkyl groups in accordance with the above definitions; the expression heteroaralkyl refers to an aralkyl group as defined above in which one or more carbon atoms have been replaced by an oxygen, nitrogen or sulphur atom; and the expression "optionally substituted" refers to groups in which one or more hydrogen atoms optionally have been replaced by fluorine, chlorine, bromine or iodine atoms or by OH, =O, SH, =S, NH 2, =NH or NO 2 groups and wherein this expression refers furthermore to groups that are optionally substituted by one or more unsubstituted C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1- C 6 heteroalkyl, C 3 -C 10 cycloalkyl, C 2 -C 9 heterocycloalkyl, C 6 -C 10 aryl, C 1 -C 9 heteroaryl, C 7 -C 12 aralkyl or C 2 -C 11 heteroaralkyl groups. X is O or NH; U-V are selected from the following groups: R 1 is a group of formula -CH 2 Ar wherein Ar is an optionally substitured aryl or heteroaryl group; R 4 and R 8 together are a group of formula -(CH 2) n - wherein this group may optionally be substituted and n is 2, 3, 4 or 5; R 5, R 6 and R 7 are independently hydrogen or C 1-4 alkyl; R 9 is a hydrogen atom, an alkyl, an alkenyl, an alkynyl, a heteroalkyl, a cycloalkyl, a heterocycloalkyl, an alkylcycloalkyl, a heteroalkylcycloalkyl, an aryl, a heteroaryl, an aralkyl or a heteroaralkyl group; and R 10 is H or methyl;