A gastroretentive dosage form (GRDF) for extended retention in a human stomach, comprising: a. a body comprising at least two arms, the body configured to transform between a collapsed configuration for ingestion, an expanded configuration for retention within the stomach and a disassembled configuration wherein after a predetermined time period has elapsed, the GRDF mechanically disassembles into at least two parts such that each of the disassembled parts of the GRDF is sized for exiting the stomach; and b. an erodible insert comprising a therapeutic agent, a diagnostic agent, an electronical device, or a combination thereof; wherein the disassembled configuration is induced by at least partial erosion of the erodible insert and wherein at least a portion of at least one arm of said at least two arms forms a sleeve, tube or shell, wherein said sleeve, tube or shell of said at least one arm comprises a cavity and at least one opening, wherein said erodible insert is housed in said cavity, wherein said at least one opening is configured to expose said erodible insert housed in said cavity to gastric fluid, wherein an uncoated surface area on said erodible insert overlaps with said at least one opening in said sleeve, tube or shell, thereby defining at least one overlapping area exposed to gastric fluid, and wherein a sum area of said at least one overlapping area is less than 59.8 mm 2, or less than 40.7 mm 2, or less than 15.5 mm 2. a. a body comprising at least two arms, the body configured to transform between a collapsed configuration for ingestion, an expanded configuration for retention within the stomach and a disassembled configuration wherein after a predetermined time period has elapsed, the GRDF mechanically disassembles into at least two parts such that each of the disassembled parts of the GRDF is sized for exiting the stomach; and b. an erodible insert comprising a therapeutic agent, a diagnostic agent, an electronical device, or a combination thereof; wherein the disassembled configuration is induced by at least partial erosion of the erodible insert and wherein at least a portion of at least one arm of said at least two arms forms a sleeve, tube or shell, wherein said sleeve, tube or shell of said at least one arm comprises a cavity and at least one opening, wherein said erodible insert is housed in said cavity, wherein said at least one opening is configured to expose said erodible insert housed in said cavity to gastric fluid, wherein an uncoated surface area on said erodible insert overlaps with said at least one opening in said sleeve, tube or shell, thereby defining at least one overlapping area exposed to gastric fluid, and wherein a sum area of said at least one overlapping area is less than 59.8 mm 2, or less than 40.7 mm 2, or less than 15.5 mm 2. wherein said sleeve, tube or shell of said at least one arm comprises a cavity and at least one opening, wherein said erodible insert is housed in said cavity, wherein said at least one opening is configured to expose said erodible insert housed in said cavity to gastric fluid, wherein said erodible insert is housed in said cavity, wherein said at least one opening is configured to expose said erodible insert housed in said cavity to gastric fluid, wherein an uncoated surface area on said erodible insert overlaps with said at least one opening in said sleeve, tube or shell, thereby defining at least one overlapping area exposed to gastric fluid, and wherein a sum area of said at least one overlapping area is less than 59.8 mm 2, or less than 40.7 mm 2, or less than 15.5 mm 2.