An aseptic coupling device for a tube, the device comprising: · a tubular insert defining a channel and having both a first end segment (20.1) provided with means for connecting it to the tube and also a second end segment (20.2) for extending outside the tube, the tubular insert being provided with a cantilevered rod extending axially inside the channel so as to have a free end portion (25.1) projecting out from the second end segment of the insert; and · an annular body comprising both a first end segment (30.1) mounted on the second end segment of the insert and also a second end segment (30.2) projecting axially from the second end segment of the insert so as to co-operate therewith to define a housing in register with the free end portion of the rod for receiving an annular sealing element of the device that is placed between a front face of the second end segment of the insert and an internal lip of the second segment of the annular body and that is deformable between a first state in which the sealing element defines a fluid flow section greater than the cross section of the rod and a second state in which the sealing element tightly surrounds the rod, the sealing element being arranged to be taken from its first state to its second state under the effect of axial compression; and wherein: · the sealing element has a front face projecting from the second segment of the annular body with a protective film removably fastened thereto, the film having a pull-tongue folded down thereon with a first end connected to an edge of the protective film and a second end projecting from the edge of the film that is opposite from the first end of the pull-tongue; and · the first end segment of the body is mounted on the insert so as to be movable axially between a projecting position in which it projects axially from the insert and in which the sealing element is in its first state, and a flush position in which it is flush with the insert and in which the sealing element is compressed axially sufficiently to be in its second state. · a tubular insert defining a channel and having both a first end segment (20.1) provided with means for connecting it to the tube and also a second end segment (20.2) for extending outside the tube, the tubular insert being provided with a cantilevered rod extending axially inside the channel so as to have a free end portion (25.1) projecting out from the second end segment of the insert; and · an annular body comprising both a first end segment (30.1) mounted on the second end segment of the insert and also a second end segment (30.2) projecting axially from the second end segment of the insert so as to co-operate therewith to define a housing in register with the free end portion of the rod for receiving an annular sealing element of the device that is placed between a front face of the second end segment of the insert and an internal lip of the second segment of the annular body and that is deformable between a first state in which the sealing element defines a fluid flow section greater than the cross section of the rod and a second state in which the sealing element tightly surrounds the rod, the sealing element being arranged to be taken from its first state to its second state under the effect of axial compression; · the sealing element has a front face projecting from the second segment of the annular body with a protective film removably fastened thereto, the film having a pull-tongue folded down thereon with a first end connected to an edge of the protective film and a second end projecting from the edge of the film that is opposite from the first end of the pull-tongue; and · the first end segment of the body is mounted on the insert so as to be movable axially between a projecting position in which it projects axially from the insert and in which the sealing element is in its first state, and a flush position in which it is flush with the insert and in which the sealing element is compressed axially sufficiently to be in its second state.