Method using a guide having a guide part (1; 12) and having a guide component (2; 14) guided and movable via the guide part (1; 12), wherein a sensor is provided in the case of the guide component (2; 14) to detect a vibration signal, and wherein an analysis device is provided in the case of the guide component (2; 14) to analyse the vibration signal detected by the sensor, wherein the guide component is a guide carriage and the guide part is a guide rail, or wherein the guide component is a threaded nut and the guide part is a guide spindle, wherein the vibration signal detected by the sensor is digitally filtered and a movement profile of the guide component (2; 14) is determined based on the digitally filtered signal, wherein multiple parts of the movement profile of the guide component (2; 14) are determined via the analysis device, wherein the parts are several of the following parts: a standstill profile and/or a starting profile and/or an acceleration profile and/or a profile of constant velocity and/or a braking profile, wherein the vibration signal of a determined part of the movement profile is used for the fatigue detection, wherein the analysis device determines one or more characteristic(s) in the vibration signal of a part of the movement profile, wherein the characteristic or the characteristics is/are selected from the following characteristics: mean value, mean absolute deviation, root mean square, wherein the determined characteristic or the determined characteristics can be stored in a memory, wherein the analysis device compares the determined characteristic or the determined characteristics with the corresponding stored characteristics, wherein the analysis device presumes a non-change of the characteristic(s) if it or they is/are below a limit or upper limit and/or above a limit or lower limit and/or between two limits (64, 66), wherein the characteristic or the characteristics is/are used in a computation of the limit (64, 66) or the limits (64, 66) and the limit (64, 66) or the limits (64, 66) is/are adaptively adjusted in this way. wherein the guide component is a guide carriage and the guide part is a guide rail, or wherein the guide component is a threaded nut and the guide part is a guide spindle, wherein the vibration signal detected by the sensor is digitally filtered and a movement profile of the guide component (2; 14) is determined based on the digitally filtered signal, wherein multiple parts of the movement profile of the guide component (2; 14) are determined via the analysis device, wherein the parts are several of the following parts: a standstill profile and/or a starting profile and/or an acceleration profile and/or a profile of constant velocity and/or a braking profile, wherein the vibration signal of a determined part of the movement profile is used for the fatigue detection, wherein the analysis device determines one or more characteristic(s) in the vibration signal of a part of the movement profile, wherein the characteristic or the characteristics is/are selected from the following characteristics: mean value, mean absolute deviation, root mean square, wherein the determined characteristic or the determined characteristics can be stored in a memory, wherein the analysis device compares the determined characteristic or the determined characteristics with the corresponding stored characteristics, wherein the analysis device presumes a non-change of the characteristic(s) if it or they is/are below a limit or upper limit and/or above a limit or lower limit and/or between two limits (64, 66), wherein the characteristic or the characteristics is/are used in a computation of the limit (64, 66) or the limits (64, 66) and the limit (64, 66) or the limits (64, 66) is/are adaptively adjusted in this way.