A method for determining cardiovascular information in the form of a fractional flow reserve using a computer system, comprising the steps of: a) receiving image data including a plurality of coronary arteries originating from an aorta; b) processing the image data to generate three-dimensional shape models of the coronary arteries; c) simulating a blood flow for the generated three-dimensional shape models of the coronary arteries; and d) determining the fractional flow reserve of the coronary arteries based on a blood flow simulation result, wherein the step c) of simulating the blood flow includes the following steps: c1) Applying a computational fluid dynamics model to the three-dimensional shape models of the coronary arteries, c2) Combining a lumped parameter model with the computational fluid dynamics model, characterized in that the lumped parameter model is a simplified coronary artery circulation model consisting of coronary arteries, capillaries of the coronary arteries and coronary veins, wherein the step c) of simulating the blood flow further includes the following steps: c3) finding lengths of centerlines of the three-dimensional shape models of the coronary arteries, c4) setting resistance values of the capillaries of the coronary arteries based on a ratio of blood flow rates in the coronary arteries when combining the simplified coronary artery circulation model with the computational fluid dynamics model, wherein the ratio of the blood flow rates in the coronary arteries is set based on a ratio of the lengths of the centerlines of the three-dimensional shape models of the coronary arteries as determined by the following formula: Q LAD: Q LCX: Q RCA = l LAD: l LCX: 1 α / l RCA RV + 1 / l RCA LV where - Q LAD is a blood flow rate of a left anterior descending coronary artery, - l LAD is a length of a left anterior descending coronary artery, - Q LCX is a blood flow rate of a left circumflex coronary artery, - l LCX is a length of a left circumflex coronary artery, - Q RCA is a blood flow rate of a right coronary artery, l RCA is a length of a right coronary artery, - (l RCA) RV is a length of a portion of a right coronary artery for supplying blood to a right ventricle, - (l RCA) LV is a length of a portion of a right coronary artery for supplying blood to a left ventricle, and - α is a correction coefficient of a blood vessel for supplying blood to a right ventricle. a) receiving image data including a plurality of coronary arteries originating from an aorta; b) processing the image data to generate three-dimensional shape models of the coronary arteries; c) simulating a blood flow for the generated three-dimensional shape models of the coronary arteries; and d) determining the fractional flow reserve of the coronary arteries based on a blood flow simulation result, c1) Applying a computational fluid dynamics model to the three-dimensional shape models of the coronary arteries, c2) Combining a lumped parameter model with the computational fluid dynamics model, c3) finding lengths of centerlines of the three-dimensional shape models of the coronary arteries, c4) setting resistance values of the capillaries of the coronary arteries based on a ratio of blood flow rates in the coronary arteries when combining the simplified coronary artery circulation model with the computational fluid dynamics model, wherein the ratio of the blood flow rates in the coronary arteries is set based on a ratio of the lengths of the centerlines of the three-dimensional shape models of the coronary arteries as determined by the following formula: Q LAD: Q LCX: Q RCA = l LAD: l LCX: 1 α / l RCA RV + 1 / l RCA LV where - Q LAD is a blood flow rate of a left anterior descending coronary artery, - l LAD is a length of a left anterior descending coronary artery, - Q LCX is a blood flow rate of a left circumflex coronary artery, - l LCX is a length of a left circumflex coronary artery, - Q RCA is a blood flow rate of a right coronary artery, l RCA is a length of a right coronary artery, - (l RCA) RV is a length of a portion of a right coronary artery for supplying blood to a right ventricle, - (l RCA) LV is a length of a portion of a right coronary artery for supplying blood to a left ventricle, and - α is a correction coefficient of a blood vessel for supplying blood to a right ventricle. - Q LAD is a blood flow rate of a left anterior descending coronary artery, - l LAD is a length of a left anterior descending coronary artery, - Q LCX is a blood flow rate of a left circumflex coronary artery, - l LCX is a length of a left circumflex coronary artery, - Q RCA is a blood flow rate of a right coronary artery, l RCA is a length of a right coronary artery, - (l RCA) RV is a length of a portion of a right coronary artery for supplying blood to a right ventricle, - (l RCA) LV is a length of a portion of a right coronary artery for supplying blood to a left ventricle, and - α is a correction coefficient of a blood vessel for supplying blood to a right ventricle.