A compound of Formula (Ia): or pharmaceutically acceptable salts, hydrates, solvates, clathrates, polymorphs, stereoisomers thereof wherein: R1 and R2 are independently selected from the group consisting of hydrogen, C 1-4 alkyl, hydroxyC 1-4 alkyl, and C 1-4 alkyl-O-C 1-4 alkyl; R3 is selected from the group consisting of C 1-6 alkyl, haloC 1-6 alkyl, OH, O-C 1-6 alkyl, C 1-6 alkyl-O-C 1-6 alkyl, CN, NO 2 and halogen; R4 is independently selected from the group consisting of C 1-6 alkyl, haloC 1-6 alkyl and halogen; A is selected from the group consisting of S, SO, and SO 2; B is selected from the group consisting of CR iv R v, O, and NR ii; C is selected from the group consisting of C 1-6 alkyl, haloC 1-6 alkyl, C 3-6 cycloalkyl optionally substituted with one or more R5, C 3-6 heterocycloalkyl optionally substituted with one or more R5, aryl optionally substituted with one or more R5, heteroaryl optionally substituted with one or more R5, C 1-6 alkyl-O-C 1-6 alkyl, C 1-6 alkyl-O-aryl, C 1-6 alkyl-O-heteroaryl, C 1-6 alkyl-O-C 3-6 heterocycloalkyl, aryl-O-aryl, and aryl-O-heteroaryl; R5 is selected from the group consisting of C 1-6 alkyl, haloC 1-6 alkyl, O-C 1-6 alkyl, C 3-6 cycloalkyl, C 3-6 heterocycloalkyl, aryl, heteroaryl, O-aryl, O-aryl-O-C 1-6 alkyl, O-heteroaryl, O-C 3-6 heterocycloalkyl, O-haloC 1-6 alkyl, OH, CN, NO 2, SF 6, halogen and COOR i; n is an integer comprised from 0 to 2; m is an integer comprised from 0 to 2; R i is independently selected from the group consisting of hydrogen and C 1-6 alkyl; R ii is independently selected from the group consisting of hydrogen and C 1-6 alkyl; R iv and R v are independently selected from the group consisting of hydrogen, C 1-6 alkyl and hydroxyC 1-6 alkyl; provided that: a) when A is S, B is O, R1 and R2 are both CH 3, R3 and R4 are both H, C is not one of b) when A is S, B is O, R1 and R2 are respectively CH 3 and H, R3 and R4 are both H, C is not one of c) when A is S, B is O, R1 and R2 are respectively isopropyl and H, R3 and R4 are both H, C is not one of d) when A is S, B is O, R1 and R2 are both H, R3 and R4 are both H, C is not one of e) when A is S, B is O, R1 and R2 are respectively H and CH 2 CH 2 OH, R3 and R4 are both H, C is not phenyl. R1 and R2 are independently selected from the group consisting of hydrogen, C 1-4 alkyl, hydroxyC 1-4 alkyl, and C 1-4 alkyl-O-C 1-4 alkyl; R3 is selected from the group consisting of C 1-6 alkyl, haloC 1-6 alkyl, OH, O-C 1-6 alkyl, C 1-6 alkyl-O-C 1-6 alkyl, CN, NO 2 and halogen; R4 is independently selected from the group consisting of C 1-6 alkyl, haloC 1-6 alkyl and halogen; A is selected from the group consisting of S, SO, and SO 2; B is selected from the group consisting of CR iv R v, O, and NR ii; C is selected from the group consisting of C 1-6 alkyl, haloC 1-6 alkyl, C 3-6 cycloalkyl optionally substituted with one or more R5, C 3-6 heterocycloalkyl optionally substituted with one or more R5, aryl optionally substituted with one or more R5, heteroaryl optionally substituted with one or more R5, C 1-6 alkyl-O-C 1-6 alkyl, C 1-6 alkyl-O-aryl, C 1-6 alkyl-O-heteroaryl, C 1-6 alkyl-O-C 3-6 heterocycloalkyl, aryl-O-aryl, and aryl-O-heteroaryl; R5 is selected from the group consisting of C 1-6 alkyl, haloC 1-6 alkyl, O-C 1-6 alkyl, C 3-6 cycloalkyl, C 3-6 heterocycloalkyl, aryl, heteroaryl, O-aryl, O-aryl-O-C 1-6 alkyl, O-heteroaryl, O-C 3-6 heterocycloalkyl, O-haloC 1-6 alkyl, OH, CN, NO 2, SF 6, halogen and COOR i; n is an integer comprised from 0 to 2; m is an integer comprised from 0 to 2; R i is independently selected from the group consisting of hydrogen and C 1-6 alkyl; R ii is independently selected from the group consisting of hydrogen and C 1-6 alkyl; R iv and R v are independently selected from the group consisting of hydrogen, C 1-6 alkyl and hydroxyC 1-6 alkyl; provided that: a) when A is S, B is O, R1 and R2 are both CH 3, R3 and R4 are both H, C is not one of b) when A is S, B is O, R1 and R2 are respectively CH 3 and H, R3 and R4 are both H, C is not one of c) when A is S, B is O, R1 and R2 are respectively isopropyl and H, R3 and R4 are both H, C is not one of d) when A is S, B is O, R1 and R2 are both H, R3 and R4 are both H, C is not one of e) when A is S, B is O, R1 and R2 are respectively H and CH 2 CH 2 OH, R3 and R4 are both H, C is not phenyl. a) when A is S, B is O, R1 and R2 are both CH 3, R3 and R4 are both H, C is not one of b) when A is S, B is O, R1 and R2 are respectively CH 3 and H, R3 and R4 are both H, C is not one of c) when A is S, B is O, R1 and R2 are respectively isopropyl and H, R3 and R4 are both H, C is not one of d) when A is S, B is O, R1 and R2 are both H, R3 and R4 are both H, C is not one of e) when A is S, B is O, R1 and R2 are respectively H and CH 2 CH 2 OH, R3 and R4 are both H, C is not phenyl.