A compound according to Formula II or Formula III: wherein: R 1 is C 1-4 alkyl, -CH 2 CN, -CN, C 1-4 alkoxyC 1-4 alkyl, halo-C 1-4 alkyl, -CH=N-OH, -CH=N-O-C 1-4 alkyl, -CH=N-O-(hydroxyC 1-4 alkyl), hydroxy-C 1-4 alkyl, -CH 2 OP 2, or C 3-5 cycloalkyl; R 3 is -OR a; -NHR b; -C NH 2; -C [hydroxyC 1-4 alkyl]; heterocyclyl optionally substituted with one or more substituents independently selected from OH and hydroxyC 1-4 alkyl; 5- or 6-membered heteroaryl optionally substituted with one or more C 1-4 alkyl; or R 3 is C 1-4 alkyl substituted with one or more substituents independently selected from - C [hydroxyC 1-4 alkyl] and -OR c; R a is -C 1-6 alkyl substituted with one or more substituents independently selected from -OR c, - SO 2 C 1-4 alkyl, -NHS 2 C 1-4 alkyl, and heterocyclyl which is further optionally substituted with one or more substituents independently selected from C 1-4 alkyl and hydroxyC 1-4 alkyl; or R a is H, -[CH 2 -CH 2 -O] n -H, -[CH 2 -CH 2 -O] m -CH 3, or heteroaryl optionally substituted with one or more C 1-4 alkyl; wherein n is 2-6 and m is 1-6; R b is -C 1-6 alkyl substituted with one or more substituents independently selected from -OR c, - C NH-C 1-4 alkyl, -C NH-(hydroxyC 1-4 alkyl), hydroxyC 1-4 alkyl, 5- or 6-membered heteroaryl, heterocyclyl, -SO 2 C 1-4 alkyl, and -NHS 2 C 1-4 alkyl; or R b is -S 2 heteroaryl; or R b is 4- to 7-membered heterocyclyl optionally substituted with one or more hydroxy groups; or R b is H, -OR c; -[CH 2 -CH 2 -O] n -H, -[CH 2 -CH 2 -O] m -CH 3, or heteroaryl optionally substituted with one or more C 1-4 alkyl; wherein n is 2-6 and m is 1-6; R c is H or hydroxyC 1-4 alkyl; R 2 is H, C 1-4 alkoxy, halo-C 1-4 alkoxy, halo, C 1-4 alkyl, -S-C 1-4 alkyl, or -NH-C 1-4 alkyl; R 4 is H, halo, halo-C 1-4 alkyl, C 1-4 alkyl, or C 3-5 cycloalkyl; R 5 is H, halo, CN, C 1-4 alkoxy, hydroxy-C 1-4 alkoxy, C 1-4 alkoxy-C 1-4 alkoxy, -CH=NH-O-C 1-4 alkyl, or -CH=NH-O(hydroxyC 1-4 alkyl); or R 5 is C 2-6 alkynyl optionally substituted with OH or NR g R h wherein R g and R h are independently H or C 1-4 alkyl; or R g and R h form together with the nitrogen to which they are attached a 4- to 7-membered heterocyclyl optionally containing an additional heteroatom selected from O, S, and N, wherein the heteroatom can be in its oxidized form; and wherein said heterocyclyl is optionally substituted with C 1-4 alkyl; and R 6 is halo, C 1-4 alkyl or CN; or a pharmaceutically acceptable salt thereof. R 1 is C 1-4 alkyl, -CH 2 CN, -CN, C 1-4 alkoxyC 1-4 alkyl, halo-C 1-4 alkyl, -CH=N-OH, -CH=N-O-C 1-4 alkyl, -CH=N-O-(hydroxyC 1-4 alkyl), hydroxy-C 1-4 alkyl, -CH 2 OP 2, or C 3-5 cycloalkyl; R 3 is -OR a; -NHR b; -C NH 2; -C [hydroxyC 1-4 alkyl]; heterocyclyl optionally substituted with one or more substituents independently selected from OH and hydroxyC 1-4 alkyl; 5- or 6-membered heteroaryl optionally substituted with one or more C 1-4 alkyl; or R 3 is C 1-4 alkyl substituted with one or more substituents independently selected from - C [hydroxyC 1-4 alkyl] and -OR c; R a is -C 1-6 alkyl substituted with one or more substituents independently selected from -OR c, - SO 2 C 1-4 alkyl, -NHS 2 C 1-4 alkyl, and heterocyclyl which is further optionally substituted with one or more substituents independently selected from C 1-4 alkyl and hydroxyC 1-4 alkyl; or R a is H, -[CH 2 -CH 2 -O] n -H, -[CH 2 -CH 2 -O] m -CH 3, or heteroaryl optionally substituted with one or more C 1-4 alkyl; wherein n is 2-6 and m is 1-6; R b is -C 1-6 alkyl substituted with one or more substituents independently selected from -OR c, - C NH-C 1-4 alkyl, -C NH-(hydroxyC 1-4 alkyl), hydroxyC 1-4 alkyl, 5- or 6-membered heteroaryl, heterocyclyl, -SO 2 C 1-4 alkyl, and -NHS 2 C 1-4 alkyl; or R b is -S 2 heteroaryl; or R b is 4- to 7-membered heterocyclyl optionally substituted with one or more hydroxy groups; or R b is H, -OR c; -[CH 2 -CH 2 -O] n -H, -[CH 2 -CH 2 -O] m -CH 3, or heteroaryl optionally substituted with one or more C 1-4 alkyl; wherein n is 2-6 and m is 1-6; R c is H or hydroxyC 1-4 alkyl; R 2 is H, C 1-4 alkoxy, halo-C 1-4 alkoxy, halo, C 1-4 alkyl, -S-C 1-4 alkyl, or -NH-C 1-4 alkyl; R 4 is H, halo, halo-C 1-4 alkyl, C 1-4 alkyl, or C 3-5 cycloalkyl; R 5 is H, halo, CN, C 1-4 alkoxy, hydroxy-C 1-4 alkoxy, C 1-4 alkoxy-C 1-4 alkoxy, -CH=NH-O-C 1-4 alkyl, or -CH=NH-O(hydroxyC 1-4 alkyl); or R 5 is C 2-6 alkynyl optionally substituted with OH or NR g R h wherein R g and R h are independently H or C 1-4 alkyl; or R g and R h form together with the nitrogen to which they are attached a 4- to 7-membered heterocyclyl optionally containing an additional heteroatom selected from O, S, and N, wherein the heteroatom can be in its oxidized form; and wherein said heterocyclyl is optionally substituted with C 1-4 alkyl; and R 6 is halo, C 1-4 alkyl or CN; or a pharmaceutically acceptable salt thereof.