mhurhangee/ep-ind-claims huggingface dataset:
A method for producing a polypeptide multimer that comprises a first polypeptide having an antigen-binding activity and a second polypeptide having an antigen-binding activity or no antigen-binding activity, which comprises the steps of: (a) expressing a DNA that encodes the first polypeptide and a DNA that encodes the second polypeptide; and (b) collecting the expression product of step (a) by protein A affinity chromatography, wherein the first polypeptide and the second polypeptide comprise an amino acid sequence of an antibody Fc domain or an amino acid sequence of an antibody heavy-chain constant region; wherein the antibody Fc domain or antibody heavy-chain constant region is derived from human IgG; wherein the amino acid residue at position 435, according to EU numbering, in the amino acid sequence of the Fc domain or heavy-chain constant region is histidine or arginine in the first polypeptide and arginine or histidine respectively in the second polypeptide; wherein the amino acid combination at positions 356 and 439 in the amino acid sequence of the Fc region or heavy chain constant region of the first polypeptide have been modified to amino acids with the same electric charge; and wherein the amino acid combination at positions 356 and 439 in the amino acid sequence of the Fc region or heavy chain constant region of the second polypeptide have been modified to amino acids with an electric charge opposite to that of positions 356 and 439 of the first polypeptide. (a) expressing a DNA that encodes the first polypeptide and a DNA that encodes the second polypeptide; and (b) collecting the expression product of step (a) by protein A affinity chromatography, wherein the first polypeptide and the second polypeptide comprise an amino acid sequence of an antibody Fc domain or an amino acid sequence of an antibody heavy-chain constant region;
A drive device for an electric vehicle, comprising: a casing; and a plurality of motor generators (20, 30) mounted in the casing, each of the motor generators including a plurality of fastening portions (23, 33) at which a stator (21, 31) of the motor generator is fixed to the casing, the drive device characterized in that a number of the fastening portions of one of the motor generators is coprime to a number of the fastening portions of at least one of the rest of the motor generators. a casing; and a plurality of motor generators (20, 30) mounted in the casing, each of the motor generators including a plurality of fastening portions (23, 33) at which a stator (21, 31) of the motor generator is fixed to the casing, the drive device characterized in that a number of the fastening portions of one of the motor generators is coprime to a number of the fastening portions of at least one of the rest of the motor generators.
A corona igniter assembly, comprising: an ignition coil assembly for receiving a radio frequency voltage, a firing end assembly for receiving energy from said ignition coil assembly and distributing a radio frequency electric field, said firing end assembly including a corona igniter; a metal tube including a first tube end attached to said ignition coil assembly and a second tube end attached to said firing end assembly; said metal tube including an outer surface and an oppositely facing inner surface surrounding at least a portion of said ignition coil assembly and at least a portion of said firing end assembly; said inner surface of said metal tube presenting a tube volume between said first tube end and said second tube end, said tube volume including space not occupied by said ignition coil assembly and said firing end assembly; said metal tube including at least one hole extending through said inner surface and said outer surface for allowing air to exit said tube volume; and a rubber boot filling said tube volume and providing a hermetic seal between said ignition coil assembly and said firing end assembly, wherein said rubber boot has a boot volume being greater than said tube volume. an ignition coil assembly for receiving a radio frequency voltage, a firing end assembly for receiving energy from said ignition coil assembly and distributing a radio frequency electric field, said firing end assembly including a corona igniter; a metal tube including a first tube end attached to said ignition coil assembly and a second tube end attached to said firing end assembly; said metal tube including an outer surface and an oppositely facing inner surface surrounding at least a portion of said ignition coil assembly and at least a portion of said firing end assembly; said inner surface of said metal tube presenting a tube volume between said first tube end and said second tube end, said tube volume including space not occupied by said ignition coil assembly and said firing end assembly; said metal tube including at least one hole extending through said inner surface and said outer surface for allowing air to exit said tube volume; and a rubber boot filling said tube volume and providing a hermetic seal between said ignition coil assembly and said firing end assembly, wherein said rubber boot has a boot volume being greater than said tube volume.
Method for transmitting energy to a projectile during the passage through a gun barrel, muzzle brake or the like by means of an energy transmission system, wherein - a frequency (f 2) generated by a signal generator for the energy transmission is imparted to the projectile during the passage, as a result of which the said projectile is loaded with energy, and wherein - the energy is imparted within the passage by a waveguide, which is operated below the cut-off frequency of the relevant waveguide mode (TE, TM). - a frequency (f 2) generated by a signal generator for the energy transmission is imparted to the projectile during the passage, as a result of which the said projectile is loaded with energy, and wherein - the energy is imparted within the passage by a waveguide, which is operated below the cut-off frequency of the relevant waveguide mode (TE, TM).
An ion source for a mass spectrometer comprising: an Atmospheric Pressure lonisation ("API") ionisation device comprising an Electrospray ion source, arranged and adapted to emit a stream of charged droplets; and characterised by: one or more ultrasonic transmitters or sonotrodes arranged and adapted to create one or more acoustic standing waves downstream of said ionisation device; wherein said one or more acoustic standing waves are arranged and adapted: to further nebulise said stream of droplets; and to result in a reduction of the average size of droplets in said stream of droplets. one or more ultrasonic transmitters or sonotrodes arranged and adapted to create one or more acoustic standing waves downstream of said ionisation device; wherein said one or more acoustic standing waves are arranged and adapted: to further nebulise said stream of droplets; and to result in a reduction of the average size of droplets in said stream of droplets. to further nebulise said stream of droplets; and to result in a reduction of the average size of droplets in said stream of droplets.
A method for enhancing the corrosion resistance, wear resistance, and contact resistance of an electronic or microelectronic device comprising a copper or copper alloy substrate and at least one metal-based layer on a surface of the substrate, the method comprising exposing the device to a composition comprising: a phosphorus oxide compound; an organic compound comprising a nitrogen-containing functional group selected from the group consisting of amine, aromatic heterocycle comprising nitrogen, and a combination thereof; and a solvent having a surface tension less than 50 mN/m (50 dynes/cm) as measured at 25°C, wherein the solvent is selected from the group consisting of paraffinic mineral oil, isoparaffinic mineral oil, naphthenic oil solvent, an alcohol having a boiling point of at least 90°C, and water and a surfactant, said solvent comprising water and a surfactant; characterized in that the phosphorus oxide compound is selected from the group consisting of a phosphonic acid, a phosphonate salt, a phosphonate ester, and mixtures thereof and_has the structure: wherein R 1 is a hydrocarbyl having between one and 24 carbon atoms; and R 2 and R 3 are each independently or together hydrogen, a charge balancing cation, or a hydrocarbyl having between one carbon atom and four carbon atoms. a phosphorus oxide compound; an organic compound comprising a nitrogen-containing functional group selected from the group consisting of amine, aromatic heterocycle comprising nitrogen, and a combination thereof; and a solvent having a surface tension less than 50 mN/m (50 dynes/cm) as measured at 25°C, wherein the solvent is selected from the group consisting of paraffinic mineral oil, isoparaffinic mineral oil, naphthenic oil solvent, an alcohol having a boiling point of at least 90°C, and water and a surfactant, said solvent comprising water and a surfactant; characterized in that the phosphorus oxide compound is selected from the group consisting of a phosphonic acid, a phosphonate salt, a phosphonate ester, and mixtures thereof and_has the structure: wherein R 1 is a hydrocarbyl having between one and 24 carbon atoms; and R 2 and R 3 are each independently or together hydrogen, a charge balancing cation, or a hydrocarbyl having between one carbon atom and four carbon atoms. wherein R 1 is a hydrocarbyl having between one and 24 carbon atoms; and R 2 and R 3 are each independently or together hydrogen, a charge balancing cation, or a hydrocarbyl having between one carbon atom and four carbon atoms.
Screen cover containing an insert piece located between inner and outer layers and configured to be fastened directly on an object or its carrying case wherein the insert piece is designed to be flexible, characterised in that the insert piece is designed to have variable rigidity which increases towards its fastening on the object or its carrying case.
Method for cleaning filters (22; 22'), which are in the form of solid bodies having pores and optionally having ducts open to the surface, by blasting with a gaseous blasting medium, the filter (22; 22') being arranged upstream from a suction opening (34, 34'; 52, 56), which sucks in the blasting medium and ambient air, during the blasting, characterised in that - the blasting medium contains dry snow as a blasting agent, - the blasting medium is accelerated in a blasting nozzle (16, 18; 48; 50; 58), in such a way that it strikes the filter (22; 22') at at least approximately the speed of sound, - the volumetric flow rate through the suction opening (34, 34'; 52; 56) per minute corresponds to at least ten times the volume of the filter (22; 22'), - the blasting medium being made able to penetrate the pores, in such a way that upon striking the filter material it can be rapidly evaporated or sublimated and subsequently sucked up through the pores and/or in such a way that the particles of the blasting medium are so small or become so small as a result of evaporation or sublimation that they pass through the pores. - the blasting medium contains dry snow as a blasting agent, - the blasting medium is accelerated in a blasting nozzle (16, 18; 48; 50; 58), in such a way that it strikes the filter (22; 22') at at least approximately the speed of sound, - the volumetric flow rate through the suction opening (34, 34'; 52; 56) per minute corresponds to at least ten times the volume of the filter (22; 22'), - the blasting medium being made able to penetrate the pores, in such a way that upon striking the filter material it can be rapidly evaporated or sublimated and subsequently sucked up through the pores and/or in such a way that the particles of the blasting medium are so small or become so small as a result of evaporation or sublimation that they pass through the pores.
Battery arrangement for electric powering of an industrial vehicle, the battery arrangement being removably connectable to the vehicle, wherein the battery arrangement can be set to a first state, wherein the battery arrangement is prevented from turning power off to the vehicle, and in that the battery arrangement can be set to a second state, wherein the battery arrangement is allowed to turn power off to the vehicle, characterized in that the battery arrangement comprises one or more current sensors, and wherein the battery arrangement is in the first state, when a measured current (Iout) out from the battery arrangement exceeds a first current level threshold, and wherein the battery arrangement is in the second state, when a measured current (Iout) out from the battery arrangement is below a first current level threshold during a first predetermined period of time.
A method of constructing a rotary drum filtering apparatus including: a drum structure that supports a circumferential filter medium, the drum structure having filtrate compartments communicating with openings in the filter medium for receiving liquid drained through the latter, the drum structure including a supporting drum, rib elements supported on the drum and defining the filtrate compartments which extend generally longitudinally along the drum circumference, and cover elements, each having an end mounted to the rib elements by a clip and an overlying cap, the cover elements forming a cover circumferentially around the supporting drum over the filtrate compartments, each clip having a cover element edge support portion (173, 175), and characterized by each cap having a cover element edge overlying portion (177, 179), the overlying portion (177, 179) including a plurality of tabs spaced apart along the longitudinal axis of the overlying portion (177, 179), each tab having a first portion that, when the drum is assembled, extends perpendicular to the support portion (173, 175), and a second portion angled relative to the first portion and extending parallel to the longitudinal axis of the cap, the support portion (173, 175) having tab receiving openings spaced apart along the longitudinal axis of the support portions (173, 175), the method comprising the steps of: placing the cover element end on the support portion (173, 175), placing the overlying portion (177, 179) over the cover element end and inserting each respective tab into a respective opening in the support portion (173, 175), moving the overlying portion (177, 179) along the support portion (173, 175), so that the tab second portion is then under the support portion (173, 175), thus holding the cap on the clip, with the cover element end trapped in between. placing the cover element end on the support portion (173, 175), placing the overlying portion (177, 179) over the cover element end and inserting each respective tab into a respective opening in the support portion (173, 175), moving the overlying portion (177, 179) along the support portion (173, 175), so that the tab second portion is then under the support portion (173, 175), thus holding the cap on the clip, with the cover element end trapped in between.
A cable assembly for an electrical test probe, comprising: a first end of the cable assembly connected to a probe tip; one or more signal cables; a pliable spine proximate to the one or more signal cables; a flexible housing that secures the pliable spine to the one or more signal cables; characterised in that the cable assembly further comprises an anchor at the probe tip, wherein the anchor prevents the pliable spine from moving with respect to the probe tip and connects the pliable spine to the probe tip; and a flexible boot that surrounds the one or more signal cables, the pliable spine, and the flexible housing, the flexible boot having multiple sections that are cut out. a first end of the cable assembly connected to a probe tip; one or more signal cables; a pliable spine proximate to the one or more signal cables; a flexible housing that secures the pliable spine to the one or more signal cables; characterised in that the cable assembly further comprises an anchor at the probe tip, wherein the anchor prevents the pliable spine from moving with respect to the probe tip and connects the pliable spine to the probe tip; and a flexible boot that surrounds the one or more signal cables, the pliable spine, and the flexible housing, the flexible boot having multiple sections that are cut out.
An array for amplification and sequencing of template polynucleotides, the array comprising: a plurality of wells wherein each well is exposed to an ISFET; a plurality of capture beads, wherein each capture bead comprises a single template binding site, wherein the wells and capture beads are relatively sized so that only one bead will fit into each well; a removable seal arranged to cover the wells and isolate each well from adjacent wells; and a heating element. a plurality of wells wherein each well is exposed to an ISFET; a plurality of capture beads, wherein each capture bead comprises a single template binding site, wherein the wells and capture beads are relatively sized so that only one bead will fit into each well; a removable seal arranged to cover the wells and isolate each well from adjacent wells; and a heating element.
An apparatus for plate punching and laser cutting, comprising a bearing frame on which, on one machine front, a punching unit and a laser cutting unit are assembled; said punching unit comprising two punching heads, one overlapping the other, an upper head with punches and a lower head with cavities; said laser cutting unit comprises two laser cutting heads, one overlapping the other, an upper head with a laser cutting device, and a lower head with a support frame for the plate to be processed and a fumes extraction assembly; characterised in that each of said heads is set in motion in an independent manner along an axis transversal to the direction of forward movement of a plate to be processed.
A lighting device comprising: a light emitting unit comprising a circular substrate and a plurality of light emitting devices disposed on the substrate; a lens disposed on the light emitting unit; and a ring-shaped gap member disposed between the lens and the light emitting unit and spacing the substrate and the lens by a predetermined gap, wherein the gap member comprises: a ring-shaped wall; and a reflective portion having an circular opening and extended at a predetermined inclination from an upper surface of the wall toward the center of the opening, wherein the light emitting devices are exposed through the opening, wherein the gap member is disposed on the substrate, wherein the diameter of the substrate is greater than the diameter of the opening, wherein the substrate is accommodated under the gap member, wherein the bottom surface of the reflective portion is in contact with the edge of the upper surface of the substrate, and wherein an inner circumference of the ring-shaped wall is in contact with an outer circumference of the substrate such that the light emitting unit is seated in the gap member. a light emitting unit comprising a circular substrate and a plurality of light emitting devices disposed on the substrate; a lens disposed on the light emitting unit; and a ring-shaped gap member disposed between the lens and the light emitting unit and spacing the substrate and the lens by a predetermined gap, wherein the gap member comprises: a ring-shaped wall; and a reflective portion having an circular opening and extended at a predetermined inclination from an upper surface of the wall toward the center of the opening, a ring-shaped wall; and a reflective portion having an circular opening and extended at a predetermined inclination from an upper surface of the wall toward the center of the opening, wherein the light emitting devices are exposed through the opening, wherein the gap member is disposed on the substrate, wherein the diameter of the substrate is greater than the diameter of the opening, wherein the substrate is accommodated under the gap member, wherein the bottom surface of the reflective portion is in contact with the edge of the upper surface of the substrate, and wherein an inner circumference of the ring-shaped wall is in contact with an outer circumference of the substrate such that the light emitting unit is seated in the gap member.
Method for actuating a hydraulic medium supply system of an automatic transmission of a vehicle, wherein the hydraulic medium supply system is supplied with hydraulic medium at least by a hydraulic pump (FZP-Pu) which is driven on the motor side and by a hydraulic pump (RS-Pu) which is driven on the wheel set side, wherein a cooling valve of the hydraulic medium supply system for supplying hydraulic medium is actuated as a function of sensed vehicle parameters for setting an adapted power distribution at the hydraulic pumps (FZP-Pu, RS-Pu), wherein a respectively present operating mode (BM1, BM2, BM3, BM4, BM5) of the vehicle for the actuation of the cooling valve is determined as a function of sensed vehicle parameters, characterized in that when a first operating mode, in which the vehicle is in the coasting driving state during slow travel with an additional engine start request, is sensed, the cooling valve is actuated in such a way that the cooling of the wheel set is carried out predominantly by the wheel set-side hydraulic pump (RS-Pu), and in that the cooling of the clutches and the generation of a system pressure are carried out by the hydraulic pump (FZP-Pu) which is driven on the motor side.
An assembly comprising: - at least one vehicle wheel, adapted to rotate about a vehicle wheel axis and adapted to perform an at least rolling movement on a travel surface for the vehicle; - at least one further rotating member, which can be operatively connected to said at least one vehicle wheel; - at least one transmission, adapted to transmit mechanical power between said vehicle wheel and said at least one further rotating member; wherein said transmission achieves a transmission ratio other than +1; - at least one braking device acting on said at least one further rotating member in order to brake said vehicle wheel, possibly until stopping it, by means of a braking action acting on said at least one further rotating member which is transmitted to the vehicle wheel by means of said transmission, characterised in that said assembly comprises at least one frictional braking device or an electromagnetic means adapted to apply a braking action on said at least one further rotating member in order to brake said at least one vehicle wheel or to brake said at least one vehicle wheel until stopping it, by braking said at least one further rotating member. - at least one vehicle wheel, adapted to rotate about a vehicle wheel axis and adapted to perform an at least rolling movement on a travel surface for the vehicle; - at least one further rotating member, which can be operatively connected to said at least one vehicle wheel; - at least one transmission, adapted to transmit mechanical power between said vehicle wheel and said at least one further rotating member; wherein said transmission achieves a transmission ratio other than +1; - at least one braking device acting on said at least one further rotating member in order to brake said vehicle wheel, possibly until stopping it, by means of a braking action acting on said at least one further rotating member which is transmitted to the vehicle wheel by means of said transmission,
System for descaling an internal combustion engine, descaling system comprising an injection means arranged so as to inject a cleaning fluid over an inlet 5for the inflow of a fuel-air mixture of the running engine, descaling system characterized in that it also comprises a control means arranged so as to control an opening or closing of an EGR valve of the engine according to parameters of the injected cleaning fluid.