mhurhangee/ep-ind-claims huggingface dataset:
A method of bonding a metal cutting tip to a shaft, wherein the tip includes first openings intersecting a first end surface of the tip, and the shaft includes second openings intersecting a second end surface of the shaft, the method being characterized by the steps: A. positioning elongated elements, wherein each elongated element extends into a first opening of the tip and an associated second opening of the shaft to align the first openings with the associated second openings, with brazing material disposed between the first and second end surfaces; B. applying to each elongated element a bond-blocking material for preventing brazing of the elongated elements to the brazing material; C. applying heat to the brazing material to braze the first and second end surfaces together while the first openings are maintained in alignment with the associated second openings by the elongated elements; and D. removing the elongated elements and residual bond-blocking material subsequent to step C; wherein the method further comprises between steps B and C, the step of moving the elongated members axially relative to the tip and the shaft to cause the bond-blocking material to enter the first and second openings (16, 24). A. positioning elongated elements, wherein each elongated element extends into a first opening of the tip and an associated second opening of the shaft to align the first openings with the associated second openings, with brazing material disposed between the first and second end surfaces; B. applying to each elongated element a bond-blocking material for preventing brazing of the elongated elements to the brazing material; C. applying heat to the brazing material to braze the first and second end surfaces together while the first openings are maintained in alignment with the associated second openings by the elongated elements; and D. removing the elongated elements and residual bond-blocking material subsequent to step C;
An immunogenic composition comprising: (a) a glycan consisting essentially of Globo H, stage-specific embryonic antigen-3 (SSEA-3, Gb5), stage-specific embryonic antigen-4 (SSEA-4, Sialyl Gb5), Bb4, or an immunogenic fragment thereof, wherein the glycan is conjugated with a carrier protein is diphtheria toxin cross-reacting material 197 (DT-CRM 197) or diphtheria toxoid, through a linker; and (b) an α-galactosyl-ceramide (α-GalCer) adjuvant. (a) a glycan consisting essentially of Globo H, stage-specific embryonic antigen-3 (SSEA-3, Gb5), stage-specific embryonic antigen-4 (SSEA-4, Sialyl Gb5), Bb4, or an immunogenic fragment thereof, wherein the glycan is conjugated with a carrier protein is diphtheria toxin cross-reacting material 197 (DT-CRM 197) or diphtheria toxoid, through a linker; and (b) an α-galactosyl-ceramide (α-GalCer) adjuvant.
A sealing test device for checking out the sealing of a cork stopper, which cork stopper comprises a body defining a central part and two ends (5a, 5b), the device comprising: • a cork stopper receiving chamber; • a chamber partitioning mechanism which divides the chamber in two compartments (8a, 8b), the mechanism comprising: • an adjustable insulator to said central part of the cork stopper, wherein the insulator is configured for, upon actuation, sealing hermetically the central part of the cork stopper body in relation to the outside environment, and simultaneously for arranging each end (5a, 5b) of the stopper in one of said compartments (8a, 8b), • an insulator actuation member, configured for, upon actuation, arranging the insulator on the central part of the cork stopper body; • at least one chamber compartment closing block (11a, 11b) arranged for, in operation, closing and hermetically isolating a respective compartment (8a, 8b) in relation to the outside environment and, together with said insulator, for isolating hermetically the compartments (8a, 8b) from each other; • at least one test fluid inlet arranged in at least one closing block (11a, 11b); • at least one detection member arranged for detecting head loss or for detecting test fluid in at least one of the compartments (8a, 8b); and • at least one test fluid source connected to at least one test fluid inlet. • a cork stopper receiving chamber; • a chamber partitioning mechanism which divides the chamber in two compartments (8a, 8b), the mechanism comprising: • an adjustable insulator to said central part of the cork stopper, wherein the insulator is configured for, upon actuation, sealing hermetically the central part of the cork stopper body in relation to the outside environment, and simultaneously for arranging each end (5a, 5b) of the stopper in one of said compartments (8a, 8b), • an insulator actuation member, configured for, upon actuation, arranging the insulator on the central part of the cork stopper body; • an adjustable insulator to said central part of the cork stopper, wherein the insulator is configured for, upon actuation, sealing hermetically the central part of the cork stopper body in relation to the outside environment, and simultaneously for arranging each end (5a, 5b) of the stopper in one of said compartments (8a, 8b), • an insulator actuation member, configured for, upon actuation, arranging the insulator on the central part of the cork stopper body; • at least one chamber compartment closing block (11a, 11b) arranged for, in operation, closing and hermetically isolating a respective compartment (8a, 8b) in relation to the outside environment and, together with said insulator, for isolating hermetically the compartments (8a, 8b) from each other; • at least one test fluid inlet arranged in at least one closing block (11a, 11b); • at least one detection member arranged for detecting head loss or for detecting test fluid in at least one of the compartments (8a, 8b); and • at least one test fluid source connected to at least one test fluid inlet.
A method for preparing a phase-stable suspension of cellulose II in water, having a high water retention capacity, characterized by the following steps: a. Preparing a spinning dope with 10 to 15% by weight of cellulose according to the lyocell process, b. precipitating the cellulose, whereby a material containing NMMO and cellulose is obtained, c. washing the material until it is substantially NMMO-free, d. enzymatic treatment of the moist material which has been washed free of NMMO with endoglucanase or a mixture of endoglucanases and exoglucanases e. comminution in a comminution unit, whereby a coarse cellulose suspension is obtained, f. microcomminution in a high pressure homogenizer into a stable microsuspension. a. Preparing a spinning dope with 10 to 15% by weight of cellulose according to the lyocell process, b. precipitating the cellulose, whereby a material containing NMMO and cellulose is obtained, c. washing the material until it is substantially NMMO-free, d. enzymatic treatment of the moist material which has been washed free of NMMO with endoglucanase or a mixture of endoglucanases and exoglucanases e. comminution in a comminution unit, whereby a coarse cellulose suspension is obtained, f. microcomminution in a high pressure homogenizer into a stable microsuspension.
Treatment arrangement for the treatment of a surface, with a planar electrode arrangement (2, 2') to which an electrical voltage can be supplied, and a planar shielding layer consisting of an isolating plastic, which at least partially encloses the electrode arrangement (2, 2'), the electrode arrangement (2, 2') consisting of a plastic provided with conductive additives, characterised in that the in the region of the boundary layer between the electrode arrangement (2, 2') and the shielding layer, the plastics of the electrode arrangement (2, 2') and the shielding layer are connected to one another in material-bonding manner without an additional adhesive layer by the plastics being mixed and/or cross-linked with one another in the region of the boundary layer.
An aircraft with a first vehicle part and at least one second vehicle part, which is movable relative to the first vehicle part, and a system for the contactless transfer of energy and data, the system comprising a primary line, a primary control unit, a secondary line, a secondary control unit, a transfer path with a primary coil, connected by way of the primary line to primary control unit, and a secondary coil connected by way of the secondary line to the secondary control unit, and a switching device with a signal output, wherein the primary control unit is designed to modulate data on first alternating-voltage signals and to lead the first alternating-voltage signals by way of the primary line into the primary coil, wherein the frequency of the first alternating-voltage signals without the modulated-on data is in a first frequency range that extends from 50 kHz to 10 MHz, wherein the secondary control unit is designed to receive the first alternating-voltage signals of the first frequency range from the secondary coil, and to demodulate the modulated-on data; wherein the system further comprises a feed-in line connected to the primary line, an activation line connected to the secondary line, an activation connection connected to the activation line, and a first filter arranged between the activation line and the secondary line, wherein the first filter is permeable to second alternating-voltage signals of a second frequency range while blocking the first alternating-voltage signals of the first frequency range, wherein the second frequency range extends from 50 Hz to 1000 Hz, wherein the primary coil is attached to the first vehicle part, and the secondary coil is attached to the second vehicle part that is variably positionable relative to the first vehicle part, wherein the switching device is designed to controllably apply a second alternating-voltage signal from the second frequency range to the signal output, wherein the signal output is connected to the feed-in line to transfer the second alternating-voltage signal to the same primary coil as the first alternating-voltage signals and transparently superimpose the second alternating-voltage signal on the first alternating-voltage signals, and wherein the at least one second vehicle part comprises a closeable container for oxygen masks, which container has a release mechanism that is connected to the activation connection and is adapted to open the container when it receives the second alternating-voltage signal.
A cooking appliance, in particular a freestanding oven comprising: a cooktop for accommodating one or more heating units; a top lid for covering/uncovering the cooktop; one or more hinge assemblies each for pivotably connecting the top lid to the cooktop, wherein one or more hinge assemblies each comprises: a hinge arm which is adapted to be connected to the top lid; a hinge base which is adapted to be connected to the cooktop; a hinge joint which is adapted to pivotably join the hinge arm and the hinge base; a first connecting means for non-releasably connecting the hinge arm to the top lid; a second connecting means for non-releasably connecting the hinge arm and the hinge base through the hinge joint; and a third connecting means for releasably connecting the hinge base to the cooktop; characterized in that the third connecting means comprises a screw connection comprising a vertical threaded bar which is fixed to the hinge base and adapted to protrude into an aperture on the cooktop, and a nut to be fixed on the threaded bar from the inner side of the cooktop, wherein the threaded bar is integrally provided with the hinge base as a single piece.
Pharmaceutical composition comprising an antibody or an antigen-binding fragment thereof which specifically binds human proprotein convertase subtilisin/kexin type 9 (hPCSK9) together with a pharmaceutically acceptable excipient or carrier, wherein the pharmaceutical composition is comprised in a unit dosage form, wherein the unit dosage form comprises 150 mg of the antibody or antigen-binding fragment thereof, and wherein the antibody or antigen-binding fragment thereof comprises the three heavy chain CDRs set forth in SEQ ID NOs: 76, 78, and 80 and the three light chain CDRs set forth in SEQ ID NOs: 84, 86, and 88.
A mobile terminal comprising: a first frame; a second frame movable with respect to the first frame in a first direction such that the mobile terminal is switched from a first state to a second state or in a second direction opposite to the first direction such that the mobile terminal is switched from the second state to the first state; a slide frame movable in the first direction or the second direction with respect to the second frame; and a support link comprising a first end hinged to the first frame and a second opposite end hinged to the second frame, characterised in that the second frame comprises: a front portion positioned on a front portion of the mobile terminal; and a rear portion positioned on a rear portion of the mobile terminal, and the support link is positioned between the front portion and the rear portion and comprises a variable length and a thickness corresponding to a distance between the front portion and the rear portion. a first frame; a second frame movable with respect to the first frame in a first direction such that the mobile terminal is switched from a first state to a second state or in a second direction opposite to the first direction such that the mobile terminal is switched from the second state to the first state; a slide frame movable in the first direction or the second direction with respect to the second frame; and a support link comprising a first end hinged to the first frame and a second opposite end hinged to the second frame, characterised in that the second frame comprises: a front portion positioned on a front portion of the mobile terminal; and a rear portion positioned on a rear portion of the mobile terminal, and the support link is positioned between the front portion and the rear portion and comprises a variable length and a thickness corresponding to a distance between the front portion and the rear portion. a front portion positioned on a front portion of the mobile terminal; and a rear portion positioned on a rear portion of the mobile terminal, and the support link is positioned between the front portion and the rear portion and comprises a variable length and a thickness corresponding to a distance between the front portion and the rear portion.
A method for calibrating a treatment probe including at least one transducer for generating high-intensity focused ultrasound in a target focusing area, the probe being intended to be electrically connected to a power supply source for providing an electric signal for the power supply of the transducer, characterized in that the method comprises a step for adjusting a frequency of the electric signal for the power supply of the transducer so that the variation between the maximum vibration intensity and the minimum vibration intensity of the transducer along its width is minimal, the step for adjusting the excitation frequency of the transducer comprising the sub-steps of: o supplying the transducer with a plurality of input signals having equal amplitudes and different respective frequencies, o measuring temperatures or pressures in different points of the target area for each input signal, o obtaining a temperature or pressure profile of the transducer for each input signal, o selecting from among the plurality of temperature or pressure profiles of the transducer, the temperature or pressure profile for which the variation between the maximum and the minimum temperature, respectively pressure, of the temperature or pressure profile is the smallest along the width of the transducer, o calculating the frequency of the electric signal for the power supply of the transducer from the frequency of the input signal associated with the selected temperature or pressure profile. o supplying the transducer with a plurality of input signals having equal amplitudes and different respective frequencies, o measuring temperatures or pressures in different points of the target area for each input signal, o obtaining a temperature or pressure profile of the transducer for each input signal, o selecting from among the plurality of temperature or pressure profiles of the transducer, the temperature or pressure profile for which the variation between the maximum and the minimum temperature, respectively pressure, of the temperature or pressure profile is the smallest along the width of the transducer, o calculating the frequency of the electric signal for the power supply of the transducer from the frequency of the input signal associated with the selected temperature or pressure profile.
A heat source for a laser deposition apparatus, comprising a source of laser light, an optical element to modulate the laser light to provide a beam, means for traversing the beam over a substrate in use in a predetermined direction, the beam having a leading edge and a trailing edge defined with reference to the traverse direction and having transverse edges joining the leading and trailing edges, the intensity distribution of the beam over its cross-sectional area being defined to provide a desired temperature distribution in use in the substrate characterised in that the optical element is so modulating the laser light to provide a beam having the defined intensity distribution, that the beam intensity is higher at the transverse edges of the beam than in the centre of the beam, at a given position between the leading and trailing edges.
A method for communicating multimedia data between a first device and a second device over a network, the method comprising the steps of: - at least the first device repeatedly generates multimedia data and sends said multimedia data to the second device, - at least the second device repeatedly generates quality data representative of the quality of the communication between the two devices (A, B), - at least the first device applies at least one current error correction strategy selected from a group of error correction strategies, in view of increasing the quality of the communication between the devices (A, B), - an evaluation of an effectiveness of each current error correction strategy on the quality of the communication between the two devices is carried out as a function of newly received quality data, wherein the evaluation of an effectiveness of each error correction strategy in the first device keeps track of a strategy counter (Ci) for each of the first device's current error correction strategy, the strategy counter (Ci) of a given error correction strategy being incremented at least when the packet loss for the multimedia data sent by the first device is above a chosen high threshold, and wherein the strategy counter of a given error correction strategy is reset at least when the packet loss for the multimedia data sent by the first device is below a chosen low threshold. - at least the first device repeatedly generates multimedia data and sends said multimedia data to the second device, - at least the second device repeatedly generates quality data representative of the quality of the communication between the two devices (A, B), - at least the first device applies at least one current error correction strategy selected from a group of error correction strategies, in view of increasing the quality of the communication between the devices (A, B), - an evaluation of an effectiveness of each current error correction strategy on the quality of the communication between the two devices is carried out as a function of newly received quality data, wherein the evaluation of an effectiveness of each error correction strategy in the first device keeps track of a strategy counter (Ci) for each of the first device's current error correction strategy, the strategy counter (Ci) of a given error correction strategy being incremented at least when the packet loss for the multimedia data sent by the first device is above a chosen high threshold, and wherein the strategy counter of a given error correction strategy is reset at least when the packet loss for the multimedia data sent by the first device is below a chosen low threshold.
An optical glucose sensor comprising: - a sensing region comprising a boronic acid receptor for binding to glucose and a fluorophore associated with said receptor; - an optical waveguide for directing incident light onto the sensing region; and - a hydrophilic, polymeric, glucose-permeable barrier layer comprising a semi-permeable membrane which is provided on at least a part of the sensing region, wherein a hydrophilic polymer and/or a negatively charged polymer is present within the pores of the membrane, the membrane being formed by generating the hydrophilic and/or negatively charged polymer in situ by diffusing a hydrophilic and/ or negatively charged monomer into the pores of a membrane and initiating polymerisation; wherein the sensor is adapted so that glucose enters the sensing region of the sensor through said barrier layer. - a sensing region comprising a boronic acid receptor for binding to glucose and a fluorophore associated with said receptor; - an optical waveguide for directing incident light onto the sensing region; and - a hydrophilic, polymeric, glucose-permeable barrier layer comprising a semi-permeable membrane which is provided on at least a part of the sensing region, wherein a hydrophilic polymer and/or a negatively charged polymer is present within the pores of the membrane, the membrane being formed by generating the hydrophilic and/or negatively charged polymer in situ by diffusing a hydrophilic and/ or negatively charged monomer into the pores of a membrane and initiating polymerisation;
A method of carrying out a biosensing process comprising: providing a biosensing device, the biosensing device comprising a substrate, an electrically conductive lead on the substrate, an insulating layer disposed on the lead and defining an aperture exposing a portion of the lead, and a nanostructured microelectrode disposed on the lead and in electrical communication with the exposed portion of the lead, the nanostructured microelectrode configured to generate a charge in response to a biomolecular stimulus; biasing the nanostructured microelectrode relative to a reference electrode; measuring a reference charge or a reference current flow between the nanostructured microelectrode and the reference electrode; exposing the nanostructured microelectrode to a biomolecular stimulus; measuring a charge or a current flow generated at the nanostructured microelectrode in response to the biomolecular stimulus; and determining the amount of biomolecular stimulus by comparing the measured charge against the reference charge or the measured current flow against the reference current flow. providing a biosensing device, the biosensing device comprising a substrate, an electrically conductive lead on the substrate, an insulating layer disposed on the lead and defining an aperture exposing a portion of the lead, and a nanostructured microelectrode disposed on the lead and in electrical communication with the exposed portion of the lead, the nanostructured microelectrode configured to generate a charge in response to a biomolecular stimulus; biasing the nanostructured microelectrode relative to a reference electrode; measuring a reference charge or a reference current flow between the nanostructured microelectrode and the reference electrode; exposing the nanostructured microelectrode to a biomolecular stimulus; measuring a charge or a current flow generated at the nanostructured microelectrode in response to the biomolecular stimulus; and determining the amount of biomolecular stimulus by comparing the measured charge against the reference charge or the measured current flow against the reference current flow.