A method for performing a pulse oximetry, the method comprising: emitting a light signal for a period of time; detecting a modulated light signal, the modulated light signal including a red signal and an infrared signal originating from an interaction of the light signal with a human tissue, the human tissue including a pulsatile tissue and a non-pulsatile tissue, wherein the interaction of the light signal with the human tissue includes reflection of the light signal from the human tissue; and processing the modulated light signal to estimate at least an oxygen saturation in the pulsatile tissue during the period of time, wherein the processing includes at least removing a non-pulsatile component resulting from the interaction of the light signal with the non-pulsatile tissue, wherein the removing the non-pulsatile component includes: removing a first parameter from maximums and minimums of an intensity associated with the infrared signal; and removing a second parameter from maximums and minimums of the intensity associated with the red signal, wherein the first and second parameters represent a bias generated by the non-pulsatile signal components, wherein the first parameter and the second parameter are pre-determined using a calibration process to reproduce a true value for a ratio = log I H ir I L ir / log I H red I L red, wherein I H ir is a maximum of intensity of the infrared signal, I L ir is a minimum of intensity of the infrared signal, I H red is a maximum of intensity of the red signal, and I L red is a minimum of an intensity of the red signal, or wherein the removing the non-pulsatile component includes multiplying a ratio R = I H ir − I L ir I H red − I L red by a correction factor, wherein the correction factor is predetermined during a calibration process, wherein I H ir is a maximum of intensity of the infrared signal, I L ir is a minimum of intensity of the infrared signal, I H red is a maximum of intensity of the red signal, and I L red is a minimum of intensity of the red signal. emitting a light signal for a period of time; detecting a modulated light signal, the modulated light signal including a red signal and an infrared signal originating from an interaction of the light signal with a human tissue, the human tissue including a pulsatile tissue and a non-pulsatile tissue, wherein the interaction of the light signal with the human tissue includes reflection of the light signal from the human tissue; and processing the modulated light signal to estimate at least an oxygen saturation in the pulsatile tissue during the period of time, wherein the processing includes at least removing a non-pulsatile component resulting from the interaction of the light signal with the non-pulsatile tissue, wherein the removing the non-pulsatile component includes: removing a first parameter from maximums and minimums of an intensity associated with the infrared signal; and removing a second parameter from maximums and minimums of the intensity associated with the red signal, removing a first parameter from maximums and minimums of an intensity associated with the infrared signal; and removing a second parameter from maximums and minimums of the intensity associated with the red signal, wherein the first and second parameters represent a bias generated by the non-pulsatile signal components, wherein the first parameter and the second parameter are pre-determined using a calibration process to reproduce a true value for a ratio = log I H ir I L ir / log I H red I L red, wherein I H ir is a maximum of intensity of the infrared signal, I L ir is a minimum of intensity of the infrared signal, I H red is a maximum of intensity of the red signal, and I L red is a minimum of an intensity of the red signal, or wherein the removing the non-pulsatile component includes multiplying a ratio R = I H ir − I L ir I H red − I L red by a correction factor, wherein the correction factor is predetermined during a calibration process, wherein I H ir is a maximum of intensity of the infrared signal, I L ir is a minimum of intensity of the infrared signal, I H red is a maximum of intensity of the red signal, and I L red is a minimum of intensity of the red signal.