An apparatus for treating vascular thrombosis with ultrasound, comprising: - a therapeutic ultrasonic transducer, suitable for generating focused ultrasonic waves that propagate along an emission axis; - an imaging ultrasonic transducer associated with the therapeutic ultrasonic transducer, suitable for acquiring two- or three-dimensional images (Im) of a region to be treated of a human or animal body, the region to be treated including a focal spot of the therapeutic ultrasonic transducer; characterised in that in also comprises: - a means (SMDR, FEF) for moving the focal spot of the therapeutic ultrasonic transducer along the emission axis with respect to the imaging ultrasonic transducer; - a motorised mechanical system suitable for moving the therapeutic ultrasonic transducer and the imaging ultrasonic transducer translationally along at least a first axis of movement parallel to said emission axis, and translationally or rotationally along or about a second axis of movement not parallel to the first; and - an electronic control system configured to: - drive the motorised mechanical system so as to perform a scan of the region to be treated while keeping constant, with a predefined tolerance, a distance between the imaging ultrasonic transducer and a surface of the human or animal body; and - drive the means for moving the focal spot of the therapeutic ultrasonic transducer so as to control the position of the focal spot along the emission axis during said scan. - a therapeutic ultrasonic transducer, suitable for generating focused ultrasonic waves that propagate along an emission axis; - an imaging ultrasonic transducer associated with the therapeutic ultrasonic transducer, suitable for acquiring two- or three-dimensional images (Im) of a region to be treated of a human or animal body, the region to be treated including a focal spot of the therapeutic ultrasonic transducer; - a means (SMDR, FEF) for moving the focal spot of the therapeutic ultrasonic transducer along the emission axis with respect to the imaging ultrasonic transducer; - a motorised mechanical system suitable for moving the therapeutic ultrasonic transducer and the imaging ultrasonic transducer translationally along at least a first axis of movement parallel to said emission axis, and translationally or rotationally along or about a second axis of movement not parallel to the first; and - an electronic control system configured to: - drive the motorised mechanical system so as to perform a scan of the region to be treated while keeping constant, with a predefined tolerance, a distance between the imaging ultrasonic transducer and a surface of the human or animal body; and - drive the means for moving the focal spot of the therapeutic ultrasonic transducer so as to control the position of the focal spot along the emission axis during said scan. - drive the motorised mechanical system so as to perform a scan of the region to be treated while keeping constant, with a predefined tolerance, a distance between the imaging ultrasonic transducer and a surface of the human or animal body; and - drive the means for moving the focal spot of the therapeutic ultrasonic transducer so as to control the position of the focal spot along the emission axis during said scan.