mhurhangee/ep-ind-claims huggingface dataset:
An in vitro method for enriching for one or more target DNA molecule from a sample of mixed DNA molecules comprising the steps of: a) providing a liquid sample of mixed DNA molecules comprising one or more specific target DNA molecule and reagents for specific detection of at least one of said target DNA molecules, b) formation of an emulsion of a multiple of liquid droplets from said liquid sample, c) specific detection of droplets containing at least one of said target DNA molecules, wherein each droplet contains less than 0.5, preferably less than 0.25 or even more preferably less than 0.1 of said one of more target DNA molecule on average, and d) physically selecting droplets containing at least one of said target DNA molecules, e) general amplification of DNA molecules in the coalesced selected droplets from step d), where the DNA molecules are in a total amount of less than 300fg, wherein general amplification reagents are added to the coalesced selected droplets to form a general amplification reaction mixture, and wherein an emulsion of droplets are formed from the reaction mixture. a) providing a liquid sample of mixed DNA molecules comprising one or more specific target DNA molecule and reagents for specific detection of at least one of said target DNA molecules, b) formation of an emulsion of a multiple of liquid droplets from said liquid sample, c) specific detection of droplets containing at least one of said target DNA molecules, wherein each droplet contains less than 0.5, preferably less than 0.25 or even more preferably less than 0.1 of said one of more target DNA molecule on average, and d) physically selecting droplets containing at least one of said target DNA molecules, e) general amplification of DNA molecules in the coalesced selected droplets from step d), where the DNA molecules are in a total amount of less than 300fg, wherein general amplification reagents are added to the coalesced selected droplets to form a general amplification reaction mixture, and wherein an emulsion of droplets are formed from the reaction mixture.
A method comprising: receiving a target DNS response message that is directed to an internal network device and sent from an external network device, the target DNS response message including a source address of the external network device; determining whether the target DNS response message satisfies predetermined conditions under a circumstance that a dynamic white list includes the source address included in the target DNS response message; and discarding the target DNS response message if the target DNS response message satisfies the predetermined conditions, wherein the predetermined conditions include at least a target domain in the target DNS response message not being included in a historical domain name record, each historical domain name in the historical domain name record being extracted from historical DNS response messages sent by the external network device. receiving a target DNS response message that is directed to an internal network device and sent from an external network device, the target DNS response message including a source address of the external network device; determining whether the target DNS response message satisfies predetermined conditions under a circumstance that a dynamic white list includes the source address included in the target DNS response message; and discarding the target DNS response message if the target DNS response message satisfies the predetermined conditions, wherein the predetermined conditions include at least a target domain in the target DNS response message not being included in a historical domain name record, each historical domain name in the historical domain name record being extracted from historical DNS response messages sent by the external network device.
A fusion protein of an antibody, or a fusion protein of an antigen binding fragment thereof, comprising a first heavy chain and a first light chain fusion protein, wherein the light chain fusion protein comprises: a full length variable region fused to the N-terminus of the immunoglobulin light chain constant region and a fusion peptide fused to the C-terminus of the immunoglobulin light chain constant region without a linker peptide, wherein the fusion peptide consists of a cytokine, wherein the first heavy chain comprises a full length variable region fused to the N-terminus of a heavy chain constant region, and wherein the cytokine of said fusion peptide (i) is IL2, or (ii) is human IL2, or (iii) is human IL2, wherein the length of the N-terminal region of the cytokine fusion is shortened by 1 to 10 amino acids, or (iv) is an IL2 having a mutation at one or more positions corresponding in human IL2 to D20, F42, R38, N88, or Q126. a full length variable region fused to the N-terminus of the immunoglobulin light chain constant region and a fusion peptide fused to the C-terminus of the immunoglobulin light chain constant region without a linker peptide, wherein the fusion peptide consists of a cytokine, wherein the first heavy chain comprises a full length variable region fused to the N-terminus of a heavy chain constant region, and wherein the cytokine of said fusion peptide (i) is IL2, or (ii) is human IL2, or (iii) is human IL2, wherein the length of the N-terminal region of the cytokine fusion is shortened by 1 to 10 amino acids, or (iv) is an IL2 having a mutation at one or more positions corresponding in human IL2 to D20, F42, R38, N88, or Q126. (i) is IL2, or (ii) is human IL2, or (iii) is human IL2, wherein the length of the N-terminal region of the cytokine fusion is shortened by 1 to 10 amino acids, or (iv) is an IL2 having a mutation at one or more positions corresponding in human IL2 to D20, F42, R38, N88, or Q126.
A computer-implemented method, comprising: generating a velocity model based upon seismic waveforms via a velocity model builder; receiving data representative of a physical attribute of an area surrounding one or more wells, wherein the data comprises a sediment velocity of a formation in a region (26, 90) of a subsurface filled with brine; generating an attribute model based upon the velocity model and the data; and rendering an image (78, 94) based upon the attribute model for use with seismic exploration above the region (26, 90) comprising a hydrocarbon reservoir and containing structural or stratigraphic features conducive to a presence, migration, or accumulation of hydrocarbons. generating a velocity model based upon seismic waveforms via a velocity model builder; receiving data representative of a physical attribute of an area surrounding one or more wells, wherein the data comprises a sediment velocity of a formation in a region (26, 90) of a subsurface filled with brine; generating an attribute model based upon the velocity model and the data; and rendering an image (78, 94) based upon the attribute model for use with seismic exploration above the region (26, 90) comprising a hydrocarbon reservoir and containing structural or stratigraphic features conducive to a presence, migration, or accumulation of hydrocarbons.
A system for creating an endoluminal valve from a blood vessel wall (1620, 5302, 5708), the system comprising: a tubular assembly (1660, 5300, 5704) having a longitudinal axis, a proximal end, a distal portion with a distal end, and a first lumen extending from the proximal end to a distal port (1670, 5703) located proximate the distal portion, the distal port (1670, 5703) located along the longitudinal axis, the distal portion having an outer supporting surface on a same side of the tubular assembly (1660, 5300, 5704) as the distal port (1670, 5703); and a tissue dissection probe (1683, 5304, 5702) disposed within the first lumen, the tissue dissection probe (1683, 5304, 5702) having a fluid delivery lumen extending to a fluid delivery port located at a distal end of the tissue dissection probe (1683, 5304, 5702), the tissue dissection probe (1683, 5304, 5702) configured to be inserted into the blood vessel wall (1620, 5302, 5708); characterized in that the outer supporting surface extends in a longitudinal direction and is offset from another outer surface of the tubular assembly (1660, 5300, 5704) that is on the same side of the tubular assembly (1660, 5300, 5704) as the distal port (1670, 5703) and proximal to the distal port (1670, 5703), the outer supporting surface configured to contact the blood vessel wall (1620, 5302, 5708), wherein the tissue dissection probe (1683, 5304, 5702) is configured to extend out of the distal port (1670, 5703) in an orientation that is substantially parallel to the outer supporting surface. a tubular assembly (1660, 5300, 5704) having a longitudinal axis, a proximal end, a distal portion with a distal end, and a first lumen extending from the proximal end to a distal port (1670, 5703) located proximate the distal portion, the distal port (1670, 5703) located along the longitudinal axis, the distal portion having an outer supporting surface on a same side of the tubular assembly (1660, 5300, 5704) as the distal port (1670, 5703); and a tissue dissection probe (1683, 5304, 5702) disposed within the first lumen, the tissue dissection probe (1683, 5304, 5702) having a fluid delivery lumen extending to a fluid delivery port located at a distal end of the tissue dissection probe (1683, 5304, 5702), the tissue dissection probe (1683, 5304, 5702) configured to be inserted into the blood vessel wall (1620, 5302, 5708); characterized in that the outer supporting surface extends in a longitudinal direction and is offset from another outer surface of the tubular assembly (1660, 5300, 5704) that is on the same side of the tubular assembly (1660, 5300, 5704) as the distal port (1670, 5703) and proximal to the distal port (1670, 5703), the outer supporting surface configured to contact the blood vessel wall (1620, 5302, 5708), wherein the tissue dissection probe (1683, 5304, 5702) is configured to extend out of the distal port (1670, 5703) in an orientation that is substantially parallel to the outer supporting surface.
A method of producing a lumbar support device, the method comprising: forming a support basket, characterized in that the method further comprises molding a pair of arching elements (4, 5) to a carrier of the lumbar support device by injection molding in a molding tool, and the support basket is formed by injection molding in the molding tool in which the pair of arching elements (4, 5) is molded to the carrier. forming a support basket, characterized in that the method further comprises molding a pair of arching elements (4, 5) to a carrier of the lumbar support device by injection molding in a molding tool, and the support basket is formed by injection molding in the molding tool in which the pair of arching elements (4, 5) is molded to the carrier.
A polylactic acid solid composition comprising: a polylactic acid having a weight average molecular weight of not more than 40,000, which is measured in terms of polystyrene standard by GPC; and a basic compound of an alkali metal or an alkaline earth metal, which is a residue of a molecular weight reduction accelerator, wherein the basic compound is contained in an amount in a range of 0.5 to 20 mass%; and wherein the polylactic acid solid composition has a granular form with an average particle diameter (D 50) of not more than 10 pm, which is measured by a laser diffraction scattering method.
A damper system for orthopedic devices, having a proximal fastening device and a distal fastening device which are coupled to each other and displaceable relative to each other, having a first hydraulic or pneumatic damper device, which is arranged between the fastening devices (10, 20) and has a flexion chamber and an extension chamber which are separated from each other by a movable piston and are fluidically connected to each other by at least one overflow line, characterized in that a second damper device with parallel action, and with a speed-independent hysteresis behavior, is arranged between the fastening devices (10, 20) and is designed as a tube structure damper.
An assembly for general lighting, having - a first light-generating unit for generating a diffuse light, - a second light-generating unit for generating a light directed in an emission direction, - a means for influencing the second light-generating unit, wherein the means are designed to influence the second light-generating unit in such a manner that the emission direction changes in a time-dependent manner, wherein the first light-generating unit has a light exit surface, via which the diffuse light is emitted and the second light-generating unit has a light emission area, via which the directed light is emitted, characterized in that the light emission area extends annularly about the light exit surface. - a first light-generating unit for generating a diffuse light, - a second light-generating unit for generating a light directed in an emission direction, - a means for influencing the second light-generating unit,
A method for displaying a screen on an electronic device, the method comprising the steps of: displaying a locked screen on which at least two objects are arranged, wherein each object is one of a background image, a clock object, a date or calendar object, a pattern lock object, or a shortcut icon object; detecting that an event, such as an event related to a specific function of the electronic device, occurs; and removing, from the locked screen, an object having an attribute that is not related to the attribute of the event and adjacent to another object having an attribute that is related to the attribute of the event, and displaying the event information at the location from which the object is removed, wherein the attribute of the event is related or not related to an object according to a user setting or a usage history of the electronic device, wherein displaying the event information comprises overlaying, on the locked screen, a layer including the event information corresponding to the event, the layer having a size corresponding to the object which is removed from the locked screen when the event occurs, wherein the size of the event information is adjusted to correspond to the size of the object which is removed from the locked screen. displaying a locked screen on which at least two objects are arranged, wherein each object is one of a background image, a clock object, a date or calendar object, a pattern lock object, or a shortcut icon object; detecting that an event, such as an event related to a specific function of the electronic device, occurs; and removing, from the locked screen, an object having an attribute that is not related to the attribute of the event and adjacent to another object having an attribute that is related to the attribute of the event, and displaying the event information at the location from which the object is removed, wherein the attribute of the event is related or not related to an object according to a user setting or a usage history of the electronic device, wherein displaying the event information comprises overlaying, on the locked screen, a layer including the event information corresponding to the event, the layer having a size corresponding to the object which is removed from the locked screen when the event occurs, wherein the size of the event information is adjusted to correspond to the size of the object which is removed from the locked screen.
Recreational vehicle kitchen block comprising a functional area having at least one sink and/or one hob, the functional area having at least one functional module (3, 4, 5, 6), the plan view of which is rectangular and the length of which is twice as large as its width and in which the sink and/or the hob is arranged, characterised in that the functional module has a sink having a preferably rectangular plan view, and the sink of the sink functional module has a bracket for an insert which covers the sink, the insert only partially covering the sink and preferably being held in the bracket so as to be displaceable in the longitudinal direction of the module.
Stator unit (100, 700, 701, 702, 703, 704, 705) for driving a rotor of an electrical planar motor, wherein the stator unit (100, 700, 701, 702, 703, 704, 705) comprises stator longitudinal layers with first coil conductors for interacting with first drive magnets of the rotor and stator oblique or transverse layers with second coil conductors for interacting with second drive magnets of the rotor, wherein the first coil conductors are extended in an elongated manner in a first direction, wherein the second coil conductors are extended in an elongated manner in a second direction different from the first direction, wherein the stator longitudinal layers and the stator oblique or transverse layers are arranged one above another in a third direction oriented perpendicularly to the first and second directions (12, 14), characterized in that the uppermost stator layer of the stator unit (100, 700, 701, 702, 703, 704, 705) and the lowermost stator layer of the stator unit (100, 700, 701, 702, 703, 704, 705) are each formed as a stator longitudinal layer with first coil conductors, wherein the stator longitudinal layers are arranged in the third direction at most on one side next to a stator oblique or transverse layer, wherein the stator oblique or transverse layers are arranged in the third direction at most on one side next to a stator longitudinal layer. wherein the stator longitudinal layers and the stator oblique or transverse layers are arranged one above another in a third direction oriented perpendicularly to the first and second directions (12, 14), characterized in that the uppermost stator layer of the stator unit (100, 700, 701, 702, 703, 704, 705) and the lowermost stator layer of the stator unit (100, 700, 701, 702, 703, 704, 705) are each formed as a stator longitudinal layer with first coil conductors, wherein the stator longitudinal layers are arranged in the third direction at most on one side next to a stator oblique or transverse layer, wherein the stator oblique or transverse layers are arranged in the third direction at most on one side next to a stator longitudinal layer.
A method of processing an audio signal, the audio signal having a plurality of audio objects, the method comprising: calculating (step S101), based on spatial metadata of the audio object, a panning coefficient for each of the audio objects in relation to each of a plurality of predefined channel coverage zones, the predefined channel coverage zones being defined by a plurality of endpoints distributed in a sound field; converting (step S102) the audio signal into submixes in relation to the predefined channel coverage zones based on the calculated panning coefficients and the audio objects, each of the submixes indicating a sum of components of the plurality of the audio objects in relation to one of the predefined channel coverage zones; generating (step S103) a submix gain by applying an audio processing to each of the submixes; and controlling (step S104) an object gain applied to each of the audio objects, the object gain being as a function of the panning coefficients for each of the audio objects and the submix gains in relation to each of the predefined channel coverage zones. calculating (step S101), based on spatial metadata of the audio object, a panning coefficient for each of the audio objects in relation to each of a plurality of predefined channel coverage zones, the predefined channel coverage zones being defined by a plurality of endpoints distributed in a sound field; converting (step S102) the audio signal into submixes in relation to the predefined channel coverage zones based on the calculated panning coefficients and the audio objects, each of the submixes indicating a sum of components of the plurality of the audio objects in relation to one of the predefined channel coverage zones; generating (step S103) a submix gain by applying an audio processing to each of the submixes; and controlling (step S104) an object gain applied to each of the audio objects, the object gain being as a function of the panning coefficients for each of the audio objects and the submix gains in relation to each of the predefined channel coverage zones.
An exhaust duct comprising a stiffener mechanism the exhaust duct including an upper row of flutes and a lower row of flutes generally opposite to the upper row of flutes, wherein each flute of the upper row of flutes and each flute of the lower row of flutes has an axis and is elongated therealong, the stiffener mechanism comprising: at least two flute ties coupling together at least two flutes from the upper row of flutes to at least two flutes from the lower row of flutes; and a retainer coupled to the at least two of the flute ties and extending generally perpendicularly to the axis of each of the at least two flutes from the upper row of flutes and the at least two flutes from the lower row of flutes, wherein the retainer is configured to generally restrain relative movement between the at least two flutes from the upper row of flutes and the at least two flutes from the lower row of flutes. at least two flute ties coupling together at least two flutes from the upper row of flutes to at least two flutes from the lower row of flutes; and a retainer coupled to the at least two of the flute ties and extending generally perpendicularly to the axis of each of the at least two flutes from the upper row of flutes and the at least two flutes from the lower row of flutes, wherein the retainer is configured to generally restrain relative movement between the at least two flutes from the upper row of flutes and the at least two flutes from the lower row of flutes.
Method for producing an assembly, comprising at least three components (11, 12, 13), said method having the steps of: - producing an intermediate assembly from a first component, a second component and a third component, wherein the three components (11, 12, 13) are arranged in a predetermined position with respect to one another, wherein, during production of the intermediate assembly, a cavity is created between the components (11, 12, 13) which comprises a first region, which extends substantially between the second component and the third component, and comprises a second region, which extends substantially between the second component and the first component, - producing a first adhesive connection between the second component and the third component, and - producing a second adhesive connection between the first component and the second component, characterized in that the second component has an aperture and in that, in order to produce the first adhesive connection, an adhesive is introduced into the first region of the cavity through the aperture, and in that the first component has an aperture, wherein, in order to produce the second adhesive connection, an adhesive is introduced into the second region of the cavity through the aperture, wherein first of all the first adhesive connection is produced and then the second adhesive connection. - producing an intermediate assembly from a first component, a second component and a third component, wherein the three components (11, 12, 13) are arranged in a predetermined position with respect to one another, wherein, during production of the intermediate assembly, a cavity is created between the components (11, 12, 13) which comprises a first region, which extends substantially between the second component and the third component, and comprises a second region, which extends substantially between the second component and the first component, - producing a first adhesive connection between the second component and the third component, and - producing a second adhesive connection between the first component and the second component,