A compound of Formula or a pharmaceutically acceptable salt thereof, wherein: X is -S - or -SO 2 -; each R 1 and R 2 is independently C 1-6 alkylene-R 4, -N(R 3)-C -R 4, -C -N(R 3)-R 4, -N(R 3)-C -O-R 4, -N(R 3)-C -N(R 3)-R 4, -O-C -N(R 3)-R 4,-N(R 3)-C -C 1-6 alkylene-C -R 4 or -N(R 3)-C -C 1-6 alkylene-N(R 3)-C -R 4; each R 3 is independently hydrogen, C 1-6 alkyl or aryl; each R 4 is independently C 1-6 alkyl, C 1-6 alkenyl, aryl, heteroaryl, aralkyl, heteroaralkyl, heterocyclylalkyl, heterocyclyl, cycloalkyl or cycloalkylalkyl, each of which is substituted with 0-3 occurrences of R 5, or two adjacent R 5 moieties, taken together with the atoms to which they are attached form a heterocyclyl, heteroaryl, cycloalkyl or aryl; each R 5 is independently oxo (=O), C 1-6 alkyl, C 1-6 haloalkyl, C 1-6 alkoxy, cyano, halo, -OH, -SH, -OCF 3, -SO 2 -C 1-6 alkyl, -NO 2, -N(R 7)-C -C 1-6 alkyl, -N(R 6) 2, -O-C -C 1-6 alkyl, C 3-7 cycloalkyl, (C 3-7 cycloalkyl)alkyl, aryl, aryloxy, -C -aryl, heteroaryl, aralkyl, heteroaralkyl, heterocyclylalkyl or heterocyclyl, wherein each aryl, heteroaryl or heterocyclyl is further substituted with 0-3 occurrences of R 7; each R 6 is independently hydrogen, fluoro, OH or C 1-6 alkyl; each R 7 is independently hydrogen, C 1-6 alkyl, -OH, -SH, cyano, halo, -CF 3, -OCF 3, -SO 2 -C 1-6 alkyl, -NO 2, -N(R 6)-C -C 1-6 alkyl, -N(R 6) 2 or C 1-6 alkoxy; m is 1, 2 or 3; and n is 1, 2 or 3; provided that the sum of m and n is from 2 to 4, wherein the term "aralkyl" refers to an alkyl moiety in which an alkyl hydrogen atom is replaced by an aryl group, wherein the term "aryl" refers to a monocyclic, bicyclic, or tricyclic aromatic hydrocarbon ring system, wherein the term "cycloalkyl" includes cyclic, bicyclic, tricyclic, or polycyclic non-aromatic hydrocarbon groups having 3 to 12 carbons, wherein the term "cycloalkylalkyl" refers to an alkyl group substituted with a cycloalkyl group, wherein the term "heterocyclyl" refers to 3- to 14-membered non-aromatic ring structures, whose ring structures include one to four heteroatoms independently selected from O, N and S, wherein the term "heteroaryl" refers to a 5-14 membered aromatic ring system having 1-3 ring heteroatoms if monocyclic, 1-6 ring heteroatoms if bicyclic, or 1-9 ring heteroatoms if tricyclic, said heteroatoms indendently selected from O, N and S, wherein the term "heterocyclylalkyl" refers to an alkyl group substituted with a heterocycle group, and wherein the term "heteroaralkyl" refers to an alkyl group substituted with a heteroaryl group. X is -S - or -SO 2 -; each R 1 and R 2 is independently C 1-6 alkylene-R 4, -N(R 3)-C -R 4, -C -N(R 3)-R 4, -N(R 3)-C -O-R 4, -N(R 3)-C -N(R 3)-R 4, -O-C -N(R 3)-R 4,-N(R 3)-C -C 1-6 alkylene-C -R 4 or -N(R 3)-C -C 1-6 alkylene-N(R 3)-C -R 4; each R 3 is independently hydrogen, C 1-6 alkyl or aryl; each R 4 is independently C 1-6 alkyl, C 1-6 alkenyl, aryl, heteroaryl, aralkyl, heteroaralkyl, heterocyclylalkyl, heterocyclyl, cycloalkyl or cycloalkylalkyl, each of which is substituted with 0-3 occurrences of R 5, or two adjacent R 5 moieties, taken together with the atoms to which they are attached form a heterocyclyl, heteroaryl, cycloalkyl or aryl; each R 5 is independently oxo (=O), C 1-6 alkyl, C 1-6 haloalkyl, C 1-6 alkoxy, cyano, halo, -OH, -SH, -OCF 3, -SO 2 -C 1-6 alkyl, -NO 2, -N(R 7)-C -C 1-6 alkyl, -N(R 6) 2, -O-C -C 1-6 alkyl, C 3-7 cycloalkyl, (C 3-7 cycloalkyl)alkyl, aryl, aryloxy, -C -aryl, heteroaryl, aralkyl, heteroaralkyl, heterocyclylalkyl or heterocyclyl, wherein each aryl, heteroaryl or heterocyclyl is further substituted with 0-3 occurrences of R 7; each R 6 is independently hydrogen, fluoro, OH or C 1-6 alkyl; each R 7 is independently hydrogen, C 1-6 alkyl, -OH, -SH, cyano, halo, -CF 3, -OCF 3, -SO 2 -C 1-6 alkyl, -NO 2, -N(R 6)-C -C 1-6 alkyl, -N(R 6) 2 or C 1-6 alkoxy; m is 1, 2 or 3; and n is 1, 2 or 3; provided that the sum of m and n is from 2 to 4, wherein the term "aralkyl" refers to an alkyl moiety in which an alkyl hydrogen atom is replaced by an aryl group, wherein the term "aryl" refers to a monocyclic, bicyclic, or tricyclic aromatic hydrocarbon ring system, wherein the term "cycloalkyl" includes cyclic, bicyclic, tricyclic, or polycyclic non-aromatic hydrocarbon groups having 3 to 12 carbons, wherein the term "cycloalkylalkyl" refers to an alkyl group substituted with a cycloalkyl group, wherein the term "heterocyclyl" refers to 3- to 14-membered non-aromatic ring structures, whose ring structures include one to four heteroatoms independently selected from O, N and S, wherein the term "heteroaryl" refers to a 5-14 membered aromatic ring system having 1-3 ring heteroatoms if monocyclic, 1-6 ring heteroatoms if bicyclic, or 1-9 ring heteroatoms if tricyclic, said heteroatoms indendently selected from O, N and S, wherein the term "heterocyclylalkyl" refers to an alkyl group substituted with a heterocycle group, and wherein the term "heteroaralkyl" refers to an alkyl group substituted with a heteroaryl group.