A bronchoscopy scope guide for a non-invasive ventilation patient interface, comprising: a semi-rigid scope guide tube having a principal axis along a length dimension thereof, further having an entrance guide portion and an exit guide portion; a bronchoscopy scope seal coupled to the scope guide tube for sealing between the scope guide tube and around a bronchoscopy scope, in response to the bronchoscopy scope being inserted through the scope guide tube, further to enable maintaining of a positive pressure within the patient interface during usage of the patient interface for non-invasive ventilation; and a semi-rigid grommet being disposed about an outer circumference of and flexibly coupled to the scope guide tube and located in a principal plane transverse to the principal axis of the scope guide tube, in-between the entrance and exit guide portions thereof, wherein the scope guide tube is pivotally manipulate-able about the flexible coupling of the grommet for positioning a distal end of the exit guide portion of the scope guide tube proximate, but not in contact with, one of a nasal cavity or mouth opening of a patient for assisted guidance control of the bronchoscopy scope within an interior region of the patient interface that extends from at least an interior surface of the patient interface to the patient's face, and for preventing undesirable bending or looping of the bronchoscopy scope within the interior region of the patient interface during insertion of the bronchoscopy scope into the nasal cavity or mouth opening and associated airway of the patient in performance of a bronchoscopy procedure wherein the scope guide tube and grommet form an integral component part; and wherein the integral component part further comprises the bronchoscopy scope seal. a semi-rigid scope guide tube having a principal axis along a length dimension thereof, further having an entrance guide portion and an exit guide portion; a bronchoscopy scope seal coupled to the scope guide tube for sealing between the scope guide tube and around a bronchoscopy scope, in response to the bronchoscopy scope being inserted through the scope guide tube, further to enable maintaining of a positive pressure within the patient interface during usage of the patient interface for non-invasive ventilation; and a semi-rigid grommet being disposed about an outer circumference of and flexibly coupled to the scope guide tube and located in a principal plane transverse to the principal axis of the scope guide tube, in-between the entrance and exit guide portions thereof, wherein the scope guide tube is pivotally manipulate-able about the flexible coupling of the grommet for positioning a distal end of the exit guide portion of the scope guide tube proximate, but not in contact with, one of a nasal cavity or mouth opening of a patient for assisted guidance control of the bronchoscopy scope within an interior region of the patient interface that extends from at least an interior surface of the patient interface to the patient's face, and for preventing undesirable bending or looping of the bronchoscopy scope within the interior region of the patient interface during insertion of the bronchoscopy scope into the nasal cavity or mouth opening and associated airway of the patient in performance of a bronchoscopy procedure wherein the scope guide tube and grommet form an integral component part; and wherein the integral component part further comprises the bronchoscopy scope seal.