mhurhangee/ep-ind-claims huggingface dataset:
A self-cleaving fusion protein comprising: (i) a target protein; (ii) a peptide represented by Formula I below; (iii) a domain of Sortase A having cleaving function; (iv) a tag, wherein (i) to (iv) are sequentially positioned from an amino terminal to a carboxyl terminal of the fusion protein, [Formula I] L-P-X-T-G, L represents Leucine, P represents Proline, X represents an any amino acid, T represents Threonine, G represents Glycine, and a peptide linker between (ii) a peptide represented by Formula I and (iii) a domain of Sortase A having cleaving function, the linker is represented by Sc l(GGSSRSS)GdSe, in which S represents Serine, G represents Glycine, R represents Arginine, c represents 0 to 5, d represents 0 to 5, e represents 0 to 5, and 1 represents 0 to 10. (i) a target protein; (ii) a peptide represented by Formula I below; (iii) a domain of Sortase A having cleaving function; (iv) a tag, wherein (i) to (iv) are sequentially positioned from an amino terminal to a carboxyl terminal of the fusion protein, [Formula I] L-P-X-T-G, L represents Leucine, P represents Proline, X represents an any amino acid, T represents Threonine, G represents Glycine, and a peptide linker between (ii) a peptide represented by Formula I and (iii) a domain of Sortase A having cleaving function, the linker is represented by Sc l(GGSSRSS)GdSe, in which S represents Serine, G represents Glycine, R represents Arginine, c represents 0 to 5, d represents 0 to 5, e represents 0 to 5, and 1 represents 0 to 10. L represents Leucine, P represents Proline, X represents an any amino acid, T represents Threonine, G represents Glycine, and a peptide linker between (ii) a peptide represented by Formula I and (iii) a domain of Sortase A having cleaving function, the linker is represented by Sc l(GGSSRSS)GdSe, in which S represents Serine, G represents Glycine, R represents Arginine, c represents 0 to 5, d represents 0 to 5, e represents 0 to 5, and 1 represents 0 to 10.
Device for medium or high voltage switching element gear, the device comprising: - a switching element (11, 12, 13, 15, 16) for connecting two conductors; and - a driving rod (14, 17) for operating the switching element (11, 12, 13, 15, 16), which driving rod (14, 17) is at least partially made of an insulating material to prevent short-circuiting or flashover; wherein the driving rod (14, 17) comprises at least a surface layer of an electrically high resistance material, wherein the driving rod (14, 17) is coated with electrically high resistance material characterized in that the coating is a dispersion of insulating particles and electrical conducting particles. - a switching element (11, 12, 13, 15, 16) for connecting two conductors; and - a driving rod (14, 17) for operating the switching element (11, 12, 13, 15, 16), which driving rod (14, 17) is at least partially made of an insulating material to prevent short-circuiting or flashover;
A fastener for securing a medical or surgical line with respect to a patient, the fastener comprising: an elongate braided tubular sleeve for receiving the line therethrough, the sleeve having a first end for fixing adjacent to the patient and a second end for arranging proximal to medical equipment coupled to the line; a collar (114, 116) coupled to the first end of the sleeve; an attachment member for securing the fastener with respect to the patient; a clip coupled to the attachment member; characterized in that the clip is configured to receive the collar to secure the collar to the clip, and to enable the collar to be released from the clip. an elongate braided tubular sleeve for receiving the line therethrough, the sleeve having a first end for fixing adjacent to the patient and a second end for arranging proximal to medical equipment coupled to the line; a collar (114, 116) coupled to the first end of the sleeve; an attachment member for securing the fastener with respect to the patient; a clip coupled to the attachment member; characterized in that the clip is configured to receive the collar to secure the collar to the clip, and to enable the collar to be released from the clip.
An ex-vivo or in-vitro method of obtaining expression of at least one protein of interest in a cell comprising: contacting a cell with an RNA composition comprising in vitro-synthesized RNA that encodes at least one protein of interest, wherein said RNA composition has been treated with RNase III in a buffered aqueous solution comprising magnesium cations at a concentration of about 1-4 mM and a salt providing an ionic strength equivalent to at least about 50-300 mM potassium acetate or potassium glutamate, wherein less than 0.01% of the mass of RNA in said treated RNA composition is dsRNA of a size greater than about 40 basepairs in length, such that said at least one protein of interest is expressed in said cell. contacting a cell with an RNA composition comprising in vitro-synthesized RNA that encodes at least one protein of interest, wherein said RNA composition has been treated with RNase III in a buffered aqueous solution comprising magnesium cations at a concentration of about 1-4 mM and a salt providing an ionic strength equivalent to at least about 50-300 mM potassium acetate or potassium glutamate, wherein less than 0.01% of the mass of RNA in said treated RNA composition is dsRNA of a size greater than about 40 basepairs in length, such that said at least one protein of interest is expressed in said cell.
Separation method, carried out by a computer, for separating, in a mixed acoustic signal w ( t), a specific pure component affected by reverberation and a background sound component, characterised in that it consists in separating the specific pure component x ( t) and the background sound component z ( t), using a modelling spectrogram of the mixed acoustic signal V̂ rev corresponding to the sum of a spectrogram of a specific reverberated component V̂ rev,y and a spectrogram of the background sound component V̂ z, the spectrogram of the specific reverberated component being dependent on the spectrogram of the specific pure component V̂ x according to the model: V ^ f, t rev, y = ∑ τ = 1 T V ^ f, t − τ + 1 x R f, τ wherein R is a reverberation matrix F × T, where F is the frequency dimension and T is the temporal dimension of R, f is a frequency index, t is a time index and τ is an integer between 1 and T; and iteratively calculating an estimation of the spectrogram of the background sound component V̂ z, of the spectrogram of the specific pure component V̂ x and of the reverberation matrix R by minimising a cost function between a spectrogram of the mixed signal V and the modelling spectrogram of the mixed signal V̂ rev, the cost function using a divergence ( d) between the spectrogram of the mixed signal and the modelling spectrogram of the mixed signal, especially the divergence called beta-divergence defined by: d β a | b = { 1 β β − 1 a β + β − 1 b β − βa b β − 1, β ∈ R \ 0,1 a log a b − a + b, β = 1 a b − log a b − 1, β = 0 wherein a and b are two real positive scalars and the minimisation of the cost function implementing, in order to obtain an estimation of the reverberation matrix, multiplicative update rules of the type: R ← R ⊙ V ⊙ V ^ rev ⊙ β − 2 ∗ t V ^ x V ^ rev ⊙ β − 1 ∗ t V ^ x where V̂ rev = V̂ rev,y + V̂ z; and wherein ⊙ is an operator corresponding to the element-wise matrix product (or vector);. ⊙(.) is an operator corresponding to the element-wise exponentiation of a matrix by a scalar; * t is a temporal convolution operator between two matrices defined by A ∗ t B f, τ = ∑ τ = t T A f, τ B f, τ − t + 1.
A system for evaluating joint pain in a subject, the system comprising: a) a first reagent configured to specifically bind human neutrophil α defensin; and b) a control indicator configured to indicate that a test using the system has been run correctly; wherein detection of at least 3,000 ng/ml human neutrophil α defensin in a synovial fluid sample from a joint detects infection in the joint. a) a first reagent configured to specifically bind human neutrophil α defensin; and b) a control indicator configured to indicate that a test using the system has been run correctly;
An electronic device comprising: a first critical integrated circuit; and a second critical integrated circuit in communication with the first critical integrated circuit; wherein the first critical integrated circuit comprises a first security function block configured to authenticate an identity of the second critical integrated circuit, wherein the first security function block authenticates the identity of the second critical integrated circuit according to a chip identity of the second critical integrated circuit, characterized by that the chip identity of the second integrated circuit is created using at least one pair of symmetric antifuse structures in a non-volatile memory physically unclonable function, and the chip identity of the second critical integrated circuit is determined based on which antifuse structures rupture when a programming voltage is applied. a first critical integrated circuit; and a second critical integrated circuit in communication with the first critical integrated circuit; wherein the first critical integrated circuit comprises a first security function block configured to authenticate an identity of the second critical integrated circuit, wherein the first security function block authenticates the identity of the second critical integrated circuit according to a chip identity of the second critical integrated circuit, characterized by that the chip identity of the second integrated circuit is created using at least one pair of symmetric antifuse structures in a non-volatile memory physically unclonable function, and the chip identity of the second critical integrated circuit is determined based on which antifuse structures rupture when a programming voltage is applied.
A wiper blade coupled to a wiper arm of a vehicle to wipe a windshield, comprising: a wiper strip in contact with the windshield, a wiper frame curved along its lengthwise direction and having elasticity to bring the wiper strip into contact with the windshield; a connector provided at one side of the wiper frame to be coupled with the wiper arm, wherein the wiper frame is arranged to be inclined at a predetermined angle, the connector being formed to be inclined in the direction opposite to the inclination direction of the wiper frame, and the wiper strip is formed to be inclined with respect to the wiper frame, so that the wiper strip is adapted to be brought into perpendicular contact with the windshield, when the wiper blade is coupled to the wiper arm to wipe the windshield, the wiper strip comprising a body portion, and a strip portion which is formed in a lower end portion of the body portion and which is adapted to be brought into contact with the windshield, characterized in that the wiper strip has rail grooves formed on both sides thereof and wherein the wiper blade further comprises a coupling slit formed in the wiper frame, the rail grooves of the wiper strip being slidably fitted to the coupling slit; a coupling aperture formed in one end of the coupling slit and allowing the wiper strip to be inserted thereinto; and wherein the rail grooves are formed in an upper end portion of the body portion to be opened to both sides, and the body portion is formed in an inclined wedge shape. a wiper strip in contact with the windshield, a wiper frame curved along its lengthwise direction and having elasticity to bring the wiper strip into contact with the windshield; a connector provided at one side of the wiper frame to be coupled with the wiper arm, wherein the wiper frame is arranged to be inclined at a predetermined angle, the connector being formed to be inclined in the direction opposite to the inclination direction of the wiper frame, and the wiper strip is formed to be inclined with respect to the wiper frame, so that the wiper strip is adapted to be brought into perpendicular contact with the windshield, when the wiper blade is coupled to the wiper arm to wipe the windshield, the wiper strip comprising a body portion, and a strip portion which is formed in a lower end portion of the body portion and which is adapted to be brought into contact with the windshield, characterized in that the wiper strip has rail grooves formed on both sides thereof and wherein the wiper blade further comprises a coupling slit formed in the wiper frame, the rail grooves of the wiper strip being slidably fitted to the coupling slit; a coupling aperture formed in one end of the coupling slit and allowing the wiper strip to be inserted thereinto; and wherein the rail grooves are formed in an upper end portion of the body portion to be opened to both sides, and the body portion is formed in an inclined wedge shape.
A method for improving performance in a network with geographically separated antenna ports based on determining and reporting reference signal power from a communication device to a base station, comprising: receiving, from the base station, a first reference signal associated with a first antenna port of the base station; determining a first reference signal power value for the received first reference signal; receiving, from the base station, a second reference signal associated with a second antenna port of the base station; determining a second reference signal power value for the received second reference signal; determining the difference between the first reference signal power value and the second reference signal power value; determining a third reference signal power value for the communication device based on whether said determined difference is greater or less than a predetermined threshold value; and reporting said third reference signal power value to the base station. receiving, from the base station, a first reference signal associated with a first antenna port of the base station; determining a first reference signal power value for the received first reference signal; receiving, from the base station, a second reference signal associated with a second antenna port of the base station; determining a second reference signal power value for the received second reference signal; determining the difference between the first reference signal power value and the second reference signal power value; determining a third reference signal power value for the communication device based on whether said determined difference is greater or less than a predetermined threshold value; and
Method for controlling a converter having controllable power semiconductors, wherein - actual state values x̂ ( k) describing the state of the converter are compared with desired state values x desired ( k), with control difference values being obtained, - the control difference values are fed to a control unit, which generates actuating voltage values u ( k) at its output, and - control electronics provide control signals depending on the actuating voltage values u ( k) and transmit said control signals to the power semiconductors (S1, S2) of the converter, wherein the control unit generates actuating voltage values u ( k) such that the control difference values become as small as possible, - the actual state values x̂ ( k) are calculated by an observer unit proceeding from the actuating voltage values u ( k) and taking account of measured current values x ( k), characterized in that - actual state intermediate circuit energy values ŵ ( k) are calculated by an estimator unit taking account of measured intermediate circuit energy values w ( k) of the positive-side and of the negative-side three-phase voltage source of the converter, wherein the observer unit and the estimator unit model the converter, such that the calculated actual state current values x̂ ( k) and actual state intermediate circuit energy values ŵ ( k) in the steady state correspond to the fault-free current and intermediate circuit energy values, and - the fault-free current and intermediate circuit energy values x̂ ( k), ŵ ( k) are fed to the control unit embodied as a periodic controller having a periodically time-variant gain. - actual state values x̂ ( k) describing the state of the converter are compared with desired state values x desired ( k), with control difference values being obtained, - the control difference values are fed to a control unit, which generates actuating voltage values u ( k) at its output, and - control electronics provide control signals depending on the actuating voltage values u ( k) and transmit said control signals to the power semiconductors (S1, S2) of the converter, wherein the control unit generates actuating voltage values u ( k) such that the control difference values become as small as possible, - the actual state values x̂ ( k) are calculated by an observer unit proceeding from the actuating voltage values u ( k) and taking account of measured current values x ( k), - actual state intermediate circuit energy values ŵ ( k) are calculated by an estimator unit taking account of measured intermediate circuit energy values w ( k) of the positive-side and of the negative-side three-phase voltage source of the converter, wherein the observer unit and the estimator unit model the converter, such that the calculated actual state current values x̂ ( k) and actual state intermediate circuit energy values ŵ ( k) in the steady state correspond to the fault-free current and intermediate circuit energy values, and - the fault-free current and intermediate circuit energy values x̂ ( k), ŵ ( k) are fed to the control unit embodied as a periodic controller having a periodically time-variant gain.
Tarpaulin unit (1, 30), in particular side tarpaulin unit, for a tarpaulin body of a commercial vehicle, having a tarpaulin element, a piping unit (14, 31) and at least one strap, wherein at least one end region of at least one strap is folded around at least one strap section (18, 32) of the piping unit (14, 31), characterised in that the piping unit (14, 31) in the at least one strap section (18, 32) has a smaller circumference than on at least one section outside the strap section (18, 32).
1-(4-(((6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)amino)methyl)-4-fluoropiperidin-1-yl)prop-2-en-1-one, and pharmaceutically usable salts, including mixtures thereof in all ratios, for use in treating or preventing myeloproliferative disorders or cancer, wherein the cancer is selected from Non-Hodgkin's Lymphoma mantle cell lymphoma and Non-Hodgkins's Lymphoma diffuse large b-cell lymphoma, including abc subtype.
A CMUT transducer array comprising: a first column of spaced CMUT cells on at least one silicon island; a second column of spaced CMUT cells on at least one further silicon island, the second column being staggered in alignment with the first column such that cells of the second column are partially located in spaces between successive cells of the first column, the first column and the second column being spaced apart by a gap; and a flexible foil retaining the respective silicon islands, the flexible foil comprising conductive interconnects. a first column of spaced CMUT cells on at least one silicon island; a second column of spaced CMUT cells on at least one further silicon island, the second column being staggered in alignment with the first column such that cells of the second column are partially located in spaces between successive cells of the first column, the first column and the second column being spaced apart by a gap; and a flexible foil retaining the respective silicon islands, the flexible foil comprising conductive interconnects.
A loaded printed circuit board test fixture comprising: an array of spaced interface probes extending through a probe plate and adapted for electrical connection to an external electronic test analyzer; a plurality of test probes for contacting test point locations on a loaded printed circuit board under test; a wiring board (26, 48, 80) positioned between the probe plate and the loaded printed circuit board under test for routing test signals from the test probes to the interface probes; wherein the wiring board (26, 48, 80) has at least one conductive circuit layer positioned on a transfer board (34; 50, 52; 84, 86) made of non-conductive material, and wherein the conductive circuit layer has a conductive pad, for contacting a test probe of the plurality of test probes, and a conductive trace extending to a second pad having a via positioned in a hole for receiving an interface pin from a plurality of interface pins; characterised in that the conductive circuit layer communicates with the plurality of interface pins extending through the wiring board (26, 48, 80) for routing the test signals from the conductive circuit layer to the interface probes, each interface pin having one end in contact with a respective interface probe and the other end communicating with the conductive circuit layer. an array of spaced interface probes extending through a probe plate and adapted for electrical connection to an external electronic test analyzer; a plurality of test probes for contacting test point locations on a loaded printed circuit board under test; a wiring board (26, 48, 80) positioned between the probe plate and the loaded printed circuit board under test for routing test signals from the test probes to the interface probes; wherein the wiring board (26, 48, 80) has at least one conductive circuit layer positioned on a transfer board (34; 50, 52; 84, 86) made of non-conductive material, and wherein the conductive circuit layer has a conductive pad, for contacting a test probe of the plurality of test probes, and a conductive trace extending to a second pad having a via positioned in a hole for receiving an interface pin from a plurality of interface pins; characterised in that the conductive circuit layer communicates with the plurality of interface pins extending through the wiring board (26, 48, 80) for routing the test signals from the conductive circuit layer to the interface probes, each interface pin having one end in contact with a respective interface probe and the other end communicating with the conductive circuit layer.