A blood pump system configured to pump blood into a peripheral vein for at least 1 day, wherein, when the system is operation, the mean wall shear stress in the peripheral vein is in the range of 2.5 to 10.0 Pa and the pulsatility in the outflow conduit is reduced, the centrifugal blood pump system comprising: a. a centrifugal blood pump comprising: an inlet and an outlet; an impeller disposed between the inlet and an outlet within the housing, the impeller having: an impeller pivot shaft configured to engage a top pivot bearing and a bottom pivot bearing, wherein an axial load can be shared between the top pivot bearing and the bottom pivot bearing, and wherein 0 to 100% of the axial load may be distributed to each pivot bearing; a plurality of blades on the top surface of the impeller extending radially away from a center of the impeller, the blades to direct blood received at the inlet through the pump housing and to the outlet; at least one magnet mechanically engaged to the impeller; an electric motor to magnetically engage the at least one magnet, wherein the electric motor, in operation, rotates the at least one magnet and the impeller; wherein the top pivot bearing extends from a top of the housing into the inlet, and the bottom pivot bearing extends from a bottom of the housing into the interior space of the housing; wherein there is a first gap between the impeller and a top portion of the housing, wherein the gap is between about 0.05mm and about 0.2mm; wherein the impeller has at least one lumen or bore extending parallel to a central axis of the impeller from a bottom surface through the impeller to a top surface; b. an inflow conduit having an inner diameter of 4 - 6 mm, having a first end and a second end, where the first end is fluidly connected to the inlet and the second end is configured for insertion into the lumen of a vein or configured for making a surgical anastomosis to a vein, the inflow conduit further comprising at least one side port providing controlled access to the fluid path; c. an outflow conduit with an inner diameter of 4 - 6 mm, having a first end and a second end, where the first end is fluidly connected to the outlet and the second end configured for insertion into the lumen of a vein or configured for making a surgical anastomosis to a vein, the outflow conduit further comprising at least one side port providing controlled access to the fluid path within the outflow conduit; and d. a control device for controlling the speed of the impeller, the control device including a processor for controlling the impeller speed, memory, a battery, and a cable for electrically connecting the control device to the centrifugal pump. a. a centrifugal blood pump comprising: an inlet and an outlet; an impeller disposed between the inlet and an outlet within the housing, the impeller having: an impeller pivot shaft configured to engage a top pivot bearing and a bottom pivot bearing, wherein an axial load can be shared between the top pivot bearing and the bottom pivot bearing, and wherein 0 to 100% of the axial load may be distributed to each pivot bearing; a plurality of blades on the top surface of the impeller extending radially away from a center of the impeller, the blades to direct blood received at the inlet through the pump housing and to the outlet; at least one magnet mechanically engaged to the impeller; an electric motor to magnetically engage the at least one magnet, wherein the electric motor, in operation, rotates the at least one magnet and the impeller; wherein the top pivot bearing extends from a top of the housing into the inlet, and the bottom pivot bearing extends from a bottom of the housing into the interior space of the housing; wherein there is a first gap between the impeller and a top portion of the housing, wherein the gap is between about 0.05mm and about 0.2mm; wherein the impeller has at least one lumen or bore extending parallel to a central axis of the impeller from a bottom surface through the impeller to a top surface; b. an inflow conduit having an inner diameter of 4 - 6 mm, having a first end and a second end, where the first end is fluidly connected to the inlet and the second end is configured for insertion into the lumen of a vein or configured for making a surgical anastomosis to a vein, the inflow conduit further comprising at least one side port providing controlled access to the fluid path; c. an outflow conduit with an inner diameter of 4 - 6 mm, having a first end and a second end, where the first end is fluidly connected to the outlet and the second end configured for insertion into the lumen of a vein or configured for making a surgical anastomosis to a vein, the outflow conduit further comprising at least one side port providing controlled access to the fluid path within the outflow conduit; and d. a control device for controlling the speed of the impeller, the control device including a processor for controlling the impeller speed, memory, a battery, and a cable for electrically connecting the control device to the centrifugal pump.