A 1,3,4-oxadiazole derivative compound represented by Chemical Formula I below, an optical isomer thereof, or a pharmaceutically acceptable salt thereof: in the Chemical Formula I above, L 1, L 2 and L 3 are each independently -(C 0 -C 2 alkyl)-; a, b and c are each independently N or CR 4, wherein a, b and c cannot be N at the same time, and R 4 is -H, -X or -O(C 1 -C 4 alkyl); Z is N, O, S, or nothing (null), wherein when Z is nothing (null), R 2 is also nothing (null), and L 2 and L 3 are directly linked; R 1 is -CX 2 H or -CX 3; R 2 is -H, -(C 1 -C 4 alkyl), -C(=O)-R A, -C(=O)-OR B or -C(=O)-NR C R D, wherein when Z is O or S, R 2 is nothing (null); R A is -(C 1 -C 4 alkyl), -(C 1 -C 4 alkyl)-O-(C 1 -C 4 alkyl), -(C 1 -C 4 alkyl)-C(=O)-O(C 1 -C 4 alkyl), -aryl, -heteroaryl, -NR A1 R A2, R B to R D are each independently -H, -(C 1 -C 4 alkyl), -(C 1 -C 4 alkyl)-O-(C 1 -C 4 alkyl), -(C 1 -C 4 alkyl)-C(=O)-O(C 1 -C 4 alkyl), -(C 3 -C 7 cycloalkyl), -aryl or -heteroaryl; Y is N, CH, O or S(=O) 2, when Y is N or CH, R Y1 to R Y4 are each independently -H, -X, -OH, -(C 1 -C 4 alkyl), -(C 3 -C 7 cycloalkyl), -(C 2 -C 6 heterocycloalkyl), -(C 1 -C 4 alkyl)-O-(C 1 -C 4 alkyl), -(C 1 -C 4 alkyl)-C(=O)-O(C 1 -C 4 alkyl), -C(=O)-(C 1 -C 4 alkyl), -C(=O)-O(C 1 -C 4 alkyl), -C(=O)-NR A3 R A4, -C(=O)-(C 3 -C 7 cycloalkyl), -C(=O)-(C 2 -C 6 heterocycloalkyl), -S(=O) 2 -(C 1 -C 4 alkyl), -aryl, -(C 1 -C 4 alkyl)-aryl, -heteroaryl, -(C 1 -C 4 alkyl)-heteroaryl, an amine protecting group, or wherein at least one H of -(C 1 -C 4 alkyl), -(C 3 -C 7 cycloalkyl), -(C 1 -C 4 alkyl)-O-(C 1 -C 4 alkyl), -(C 1 -C 4 alkyl)-C(=O)-O(C 1 -C 4 alkyl), -C(=O)-(C 1 -C 4 alkyl), -C(=O)-(C 3 -C 7 cycloalkyl), -C(=O)-(C 2 -C 6 heterocycloalkyl) and -S(=O) 2 -(C 1 -C 4 alkyl) may be substituted with -X or -OH; at least one H of the aryl, -(C 1 -C 4 alkyl)-aryl, heteroaryl and -(C 1 -C 4 alkyl)-heteroaryl may be substituted with -(C 1 -C 4 alkyl), -O-(C 1 -C 4 alkyl), -X, -OH or -CF 3; -(C 2 -C 6 heterocycloalkyl), -heteroaryl, -(C 1 -C 4 alkyl)heteroaryl may contain N, O or S atoms in the ring; and W is NH, CH 2 or O; when Y is O or S(=O) 2, R Y1 to R Y4 are nothing (null); m and n are each independently an integer of 1, 2 or 3; R a to R d are each independently -H or -(C 1 -C 4 alkyl); R 3 is -(C 3 -C 7 cycloalkyl), -adamantyl, -aryl or -heteroaryl, wherein at least one -H of -(C 3 -C 7 cycloalkyl), -adamantyl, -aryl or -heteroaryl may each independently be substituted with -X, -OH, -(C 1 -C 4 alkyl), -O(C 1 -C 4 alkyl), -(C=O)-(C 1 -C 4 alkyl), -C(=O)-O(C 1 -C 4 alkyl), -CF 3, -CF 2 H, -OCF 3, -NR A5 R A6, -S(=O) 2 -(C 1 -C 4 alkyl), -aryl and -heteroaryl; R A1 to R A6 are each independently -H or -(C 1 -C 4 alkyl); and X is F, Cl, Br or I. L 1, L 2 and L 3 are each independently -(C 0 -C 2 alkyl)-; a, b and c are each independently N or CR 4, wherein a, b and c cannot be N at the same time, and R 4 is -H, -X or -O(C 1 -C 4 alkyl); Z is N, O, S, or nothing (null), wherein when Z is nothing (null), R 2 is also nothing (null), and L 2 and L 3 are directly linked; R 1 is -CX 2 H or -CX 3; R 2 is -H, -(C 1 -C 4 alkyl), -C(=O)-R A, -C(=O)-OR B or -C(=O)-NR C R D, wherein when Z is O or S, R 2 is nothing (null); R A is -(C 1 -C 4 alkyl), -(C 1 -C 4 alkyl)-O-(C 1 -C 4 alkyl), -(C 1 -C 4 alkyl)-C(=O)-O(C 1 -C 4 alkyl), -aryl, -heteroaryl, -NR A1 R A2, R B to R D are each independently -H, -(C 1 -C 4 alkyl), -(C 1 -C 4 alkyl)-O-(C 1 -C 4 alkyl), -(C 1 -C 4 alkyl)-C(=O)-O(C 1 -C 4 alkyl), -(C 3 -C 7 cycloalkyl), -aryl or -heteroaryl; Y is N, CH, O or S(=O) 2, when Y is N or CH, R Y1 to R Y4 are each independently -H, -X, -OH, -(C 1 -C 4 alkyl), -(C 3 -C 7 cycloalkyl), -(C 2 -C 6 heterocycloalkyl), -(C 1 -C 4 alkyl)-O-(C 1 -C 4 alkyl), -(C 1 -C 4 alkyl)-C(=O)-O(C 1 -C 4 alkyl), -C(=O)-(C 1 -C 4 alkyl), -C(=O)-O(C 1 -C 4 alkyl), -C(=O)-NR A3 R A4, -C(=O)-(C 3 -C 7 cycloalkyl), -C(=O)-(C 2 -C 6 heterocycloalkyl), -S(=O) 2 -(C 1 -C 4 alkyl), -aryl, -(C 1 -C 4 alkyl)-aryl, -heteroaryl, -(C 1 -C 4 alkyl)-heteroaryl, an amine protecting group, or wherein at least one H of -(C 1 -C 4 alkyl), -(C 3 -C 7 cycloalkyl), -(C 1 -C 4 alkyl)-O-(C 1 -C 4 alkyl), -(C 1 -C 4 alkyl)-C(=O)-O(C 1 -C 4 alkyl), -C(=O)-(C 1 -C 4 alkyl), -C(=O)-(C 3 -C 7 cycloalkyl), -C(=O)-(C 2 -C 6 heterocycloalkyl) and -S(=O) 2 -(C 1 -C 4 alkyl) may be substituted with -X or -OH; at least one H of the aryl, -(C 1 -C 4 alkyl)-aryl, heteroaryl and -(C 1 -C 4 alkyl)-heteroaryl may be substituted with -(C 1 -C 4 alkyl), -O-(C 1 -C 4 alkyl), -X, -OH or -CF 3; -(C 2 -C 6 heterocycloalkyl), -heteroaryl, -(C 1 -C 4 alkyl)heteroaryl may contain N, O or S atoms in the ring; and W is NH, CH 2 or O; when Y is O or S(=O) 2, R Y1 to R Y4 are nothing (null); m and n are each independently an integer of 1, 2 or 3; R a to R d are each independently -H or -(C 1 -C 4 alkyl); R 3 is -(C 3 -C 7 cycloalkyl), -adamantyl, -aryl or -heteroaryl, wherein at least one -H of -(C 3 -C 7 cycloalkyl), -adamantyl, -aryl or -heteroaryl may each independently be substituted with -X, -OH, -(C 1 -C 4 alkyl), -O(C 1 -C 4 alkyl), -(C=O)-(C 1 -C 4 alkyl), -C(=O)-O(C 1 -C 4 alkyl), -CF 3, -CF 2 H, -OCF 3, -NR A5 R A6, -S(=O) 2 -(C 1 -C 4 alkyl), -aryl and -heteroaryl; R A1 to R A6 are each independently -H or -(C 1 -C 4 alkyl); and X is F, Cl, Br or I.