Device for use in molecular diagnostics testing comprising: - at least one reagent storage container (1, 710, 825), the reagent storage container (1, 710, 825) initially being sealed; - at least one opener (5, 715, 830) for unsealing the reagent storage container (1, 710, 825) by piercing; - a rotatable actuator (20, 40, 700, 800) coupled to at least one of the reagent storage container (1, 710, 825) and the opener (5, 715, 830) such that moving the actuator (15, 20, 40, 700, 800) brings the reagent storage container (1, 710, 825) and the opener (5, 715, 830) together so that the opener (5, 715, 830) unseals the reagent storage container (1, 710, 825), - a housing comprising the rotatable actuator (20, 40, 700, 800), and - locking means (855, 860, 880, 880A, 880B, 885) for temporarily preventing the reagent storage container (1, 710, 825) and the opener (5, 715, 830) from moving towards each other, the locking means comprising - a protrusion that is supported by a supporting part of the housing over a limited angle of rotation in such a way that once the actuator is rotated over an angle exceeding the angle of rotation, the protrusion is not supported anymore by the supporting part such that the actuator is able to bring the reagent storage container and the opener together, and/or - a groove (880, 880A, 880B) on the actuator that holds a pin comprised in the housing, or vice versa, in such a way that, when the pin rests in a first part of the groove, the actuator is prevented from rotating, and when the actuator is moved slightly in a direction perpendicular to the plane or rotation, the pin enters a second part of the groove extending in the direction of rotation and the actuator is allowed to rotate. - at least one reagent storage container (1, 710, 825), the reagent storage container (1, 710, 825) initially being sealed; - at least one opener (5, 715, 830) for unsealing the reagent storage container (1, 710, 825) by piercing; - a rotatable actuator (20, 40, 700, 800) coupled to at least one of the reagent storage container (1, 710, 825) and the opener (5, 715, 830) such that moving the actuator (15, 20, 40, 700, 800) brings the reagent storage container (1, 710, 825) and the opener (5, 715, 830) together so that the opener (5, 715, 830) unseals the reagent storage container (1, 710, 825), - a housing comprising the rotatable actuator (20, 40, 700, 800), and - locking means (855, 860, 880, 880A, 880B, 885) for temporarily preventing the reagent storage container (1, 710, 825) and the opener (5, 715, 830) from moving towards each other, the locking means comprising - a protrusion that is supported by a supporting part of the housing over a limited angle of rotation in such a way that once the actuator is rotated over an angle exceeding the angle of rotation, the protrusion is not supported anymore by the supporting part such that the actuator is able to bring the reagent storage container and the opener together, and/or - a groove (880, 880A, 880B) on the actuator that holds a pin comprised in the housing, or vice versa, in such a way that, when the pin rests in a first part of the groove, the actuator is prevented from rotating, and when the actuator is moved slightly in a direction perpendicular to the plane or rotation, the pin enters a second part of the groove extending in the direction of rotation and the actuator is allowed to rotate. - a protrusion that is supported by a supporting part of the housing over a limited angle of rotation in such a way that once the actuator is rotated over an angle exceeding the angle of rotation, the protrusion is not supported anymore by the supporting part such that the actuator is able to bring the reagent storage container and the opener together, and/or - a groove (880, 880A, 880B) on the actuator that holds a pin comprised in the housing, or vice versa, in such a way that, when the pin rests in a first part of the groove, the actuator is prevented from rotating, and when the actuator is moved slightly in a direction perpendicular to the plane or rotation, the pin enters a second part of the groove extending in the direction of rotation and the actuator is allowed to rotate.