An in-vivo imaging system comprising: at least one imaging modality for acquiring in-vivo imaging data of a subject in an imaging region of the modality; a reconstruction processor configured to reconstruct raw data into an image representation; a research workstation configured to provide a user with an electronic interface to the imaging modality, the workstation including a study design user interface that allows a user to one of create a new study and modify an existing study for use in the in-vivo imaging system; wherein the imaging modality, the reconstruction processor and the research workstation are in mutual communication; the workstation further including: a quantification user interface configured to enable the user to recall existing clinical study packages and allows the user to access at least one of a standardized uptake value tool, a pharmacokinetics tool, a cardiology tool, a neurology tool, an oncology tool, a bone densitometry tool, and a neo-vascularization tool; characterised in the in-vivo imaging system further including: a positioner configured for positioning an animal capsule optimally in the imaging region of the imaging modality during an imaging session; wherein the animal capsule is dockable with at least one of several docking interfaces located at a preparation area and the at least one imaging modality during the imaging session; the in-vivo imaging system further including: the animal capsule, the at least one of several docting interfaces and at least one animal monitoring and anesthesia system configured for monitoring vital signs of the subject during a sedation period, and for providing regulated anesthesia to the subject via the at least one of several docking interfaces. at least one imaging modality for acquiring in-vivo imaging data of a subject in an imaging region of the modality; a reconstruction processor configured to reconstruct raw data into an image representation; a research workstation configured to provide a user with an electronic interface to the imaging modality, the workstation including a study design user interface that allows a user to one of create a new study and modify an existing study for use in the in-vivo imaging system; wherein the imaging modality, the reconstruction processor and the research workstation are in mutual communication; the workstation further including: a quantification user interface configured to enable the user to recall existing clinical study packages and allows the user to access at least one of a standardized uptake value tool, a pharmacokinetics tool, a cardiology tool, a neurology tool, an oncology tool, a bone densitometry tool, and a neo-vascularization tool; characterised in the in-vivo imaging system further including: a positioner configured for positioning an animal capsule optimally in the imaging region of the imaging modality during an imaging session; wherein the animal capsule is dockable with at least one of several docking interfaces located at a preparation area and the at least one imaging modality during the imaging session; the in-vivo imaging system further including: the animal capsule, the at least one of several docting interfaces and at least one animal monitoring and anesthesia system configured for monitoring vital signs of the subject during a sedation period, and for providing regulated anesthesia to the subject via the at least one of several docking interfaces. a quantification user interface configured to enable the user to recall existing clinical study packages and allows the user to access at least one of a standardized uptake value tool, a pharmacokinetics tool, a cardiology tool, a neurology tool, an oncology tool, a bone densitometry tool, and a neo-vascularization tool; characterised in the in-vivo imaging system further including: a positioner configured for positioning an animal capsule optimally in the imaging region of the imaging modality during an imaging session; wherein the animal capsule is dockable with at least one of several docking interfaces located at a preparation area and the at least one imaging modality during the imaging session; the in-vivo imaging system further including: the animal capsule, the at least one of several docting interfaces and at least one animal monitoring and anesthesia system configured for monitoring vital signs of the subject during a sedation period, and for providing regulated anesthesia to the subject via the at least one of several docking interfaces. the animal capsule, the at least one of several docting interfaces and at least one animal monitoring and anesthesia system configured for monitoring vital signs of the subject during a sedation period, and for providing regulated anesthesia to the subject via the at least one of several docking interfaces.