A system for use in an orthopedic surgery on a target bone, comprising: a cut guide adjustably positionable onto the target bone via two or more coupling receptacles (331A-B) created on the target bone, the cut guide comprising: a guide body forming the cut guide, the guide body including one or more guide members (120A-D) each sized, shaped or otherwise configured to guide a cutting tool with respect to a respective cutting trajectory (150A-D); and a plurality of landing members (130A-B, 131A-B), each of the plurality of landing members (130A-B, 131A-B) including a respective coupling feature; an input interface (220, 420) configured to receive a target bone representation including a data set representing two or more landing sites (330A-B) of the target bone (X pre-coupling); a model receiver module (210, 410) configured to receive a generic post-coupling bone model (M coupling) including a data set representing a bone having the two or more coupling receptacles (331A-B) each sized, shaped or otherwise configured to receive and secure the respective coupling feature of each of the plurality of landing members (130A-B, 131A-B); a navigation-based guide coupling preparation system, including a cut guide positioning planning module configured to generate a plan for positioning the cut guide onto or conforming to the target bone, the cut guide positioning planning module including: a first registration module configured to register M coupling to X pre-coupling and create a registered generic post-coupling bone model; and a positioning plan formation module (233, 453) configured, using the registered generic post-coupling bone model, to respectively determine the two or more landing sites (330A-B) of the target bone for creating the two or more coupling receptacles (331A-B) and geometric or morphological descriptors of the two or more coupling receptacles (331A-B); and a display module configured to provide one or more of: the data set representing the two or more landing sites (330A-B) of the target bone (X pre-coupling); the generic post-coupling bone model (M coupling); the landing site (330A-B) of the target bone; and the size, shape, and geometric or morphological descriptors of the two or more coupling receptacles (331A-B) on the target bone. a cut guide adjustably positionable onto the target bone via two or more coupling receptacles (331A-B) created on the target bone, the cut guide comprising: a guide body forming the cut guide, the guide body including one or more guide members (120A-D) each sized, shaped or otherwise configured to guide a cutting tool with respect to a respective cutting trajectory (150A-D); and a plurality of landing members (130A-B, 131A-B), each of the plurality of landing members (130A-B, 131A-B) including a respective coupling feature; a guide body forming the cut guide, the guide body including one or more guide members (120A-D) each sized, shaped or otherwise configured to guide a cutting tool with respect to a respective cutting trajectory (150A-D); and a plurality of landing members (130A-B, 131A-B), each of the plurality of landing members (130A-B, 131A-B) including a respective coupling feature; an input interface (220, 420) configured to receive a target bone representation including a data set representing two or more landing sites (330A-B) of the target bone (X pre-coupling); a model receiver module (210, 410) configured to receive a generic post-coupling bone model (M coupling) including a data set representing a bone having the two or more coupling receptacles (331A-B) each sized, shaped or otherwise configured to receive and secure the respective coupling feature of each of the plurality of landing members (130A-B, 131A-B); a navigation-based guide coupling preparation system, including a cut guide positioning planning module configured to generate a plan for positioning the cut guide onto or conforming to the target bone, the cut guide positioning planning module including: a first registration module configured to register M coupling to X pre-coupling and create a registered generic post-coupling bone model; and a positioning plan formation module (233, 453) configured, using the registered generic post-coupling bone model, to respectively determine the two or more landing sites (330A-B) of the target bone for creating the two or more coupling receptacles (331A-B) and geometric or morphological descriptors of the two or more coupling receptacles (331A-B); and a first registration module configured to register M coupling to X pre-coupling and create a registered generic post-coupling bone model; and a positioning plan formation module (233, 453) configured, using the registered generic post-coupling bone model, to respectively determine the two or more landing sites (330A-B) of the target bone for creating the two or more coupling receptacles (331A-B) and geometric or morphological descriptors of the two or more coupling receptacles (331A-B); and a display module configured to provide one or more of: the data set representing the two or more landing sites (330A-B) of the target bone (X pre-coupling); the generic post-coupling bone model (M coupling); the landing site (330A-B) of the target bone; and the size, shape, and geometric or morphological descriptors of the two or more coupling receptacles (331A-B) on the target bone. the data set representing the two or more landing sites (330A-B) of the target bone (X pre-coupling); the generic post-coupling bone model (M coupling); the landing site (330A-B) of the target bone; and the size, shape, and geometric or morphological descriptors of the two or more coupling receptacles (331A-B) on the target bone.