A pneumatic tire, comprising: a tread with a designated direction to be mounted on a vehicle; an inner tread edge (Tei) to be positioned on the vehicle inner side and an outer tread edge (Teo) to be positioned on the vehicle outer side when mounted on a vehicle; a plurality of main grooves extending continuously in a tire circumferential direction so as to form a plurality of land sections between the tread edges (Tei, Teo); and a plurality of lateral grooves extending in a direction to cross the main grooves, wherein the main grooves include an inner shoulder-main groove positioned closest to the inner tread edge (Tei), an outer shoulder-main groove positioned closest to the outer tread edge (Teo), an inner center-main groove positioned between the inner shoulder-main groove and the tire equator, and an outer center-main groove positioned between the outer shoulder-main groove and the tire equator, the land sections include an inner middle land section between the inner shoulder-main groove and the inner center-main groove, and an outer middle land section between the outer shoulder-main groove and the outer center-main groove, the lateral grooves include inner middle-lateral grooves formed in the inner middle land section, and outer middle-lateral grooves formed in the outer middle land section, the inner middle-lateral grooves include a first inner middle-inclined groove that extends from the inner shoulder-main groove and terminates within the inner middle land section, and a second inner middle-inclined groove that extends from the inner center-main groove and terminates within the inner middle land section while inclining in a direction opposite that of the first inner middle-inclined groove and being arranged alternately with the first inner middle-inclined groove, the outer middle-lateral grooves include a first outer middle-inclined groove that extends from the outer shoulder-main groove and terminates within the outer middle land section, and a second outer middle-inclined groove that extends from the outer center-main groove and terminates within the outer middle land section while inclining in a direction opposite that of the first outer middle-inclined groove and being arranged alternately with the first outer middle-inclined groove, characterized in that the total number of the first and second outer middle-inclined grooves (21, 22) is set to be less than the total number of the first and second inner middle-inclined grooves (16, 17). a tread with a designated direction to be mounted on a vehicle; an inner tread edge (Tei) to be positioned on the vehicle inner side and an outer tread edge (Teo) to be positioned on the vehicle outer side when mounted on a vehicle; a plurality of main grooves extending continuously in a tire circumferential direction so as to form a plurality of land sections between the tread edges (Tei, Teo); and a plurality of lateral grooves extending in a direction to cross the main grooves, wherein the main grooves include an inner shoulder-main groove positioned closest to the inner tread edge (Tei), an outer shoulder-main groove positioned closest to the outer tread edge (Teo), an inner center-main groove positioned between the inner shoulder-main groove and the tire equator, and an outer center-main groove positioned between the outer shoulder-main groove and the tire equator, the land sections include an inner middle land section between the inner shoulder-main groove and the inner center-main groove, and an outer middle land section between the outer shoulder-main groove and the outer center-main groove, the lateral grooves include inner middle-lateral grooves formed in the inner middle land section, and outer middle-lateral grooves formed in the outer middle land section, the inner middle-lateral grooves include a first inner middle-inclined groove that extends from the inner shoulder-main groove and terminates within the inner middle land section, and a second inner middle-inclined groove that extends from the inner center-main groove and terminates within the inner middle land section while inclining in a direction opposite that of the first inner middle-inclined groove and being arranged alternately with the first inner middle-inclined groove, the outer middle-lateral grooves include a first outer middle-inclined groove that extends from the outer shoulder-main groove and terminates within the outer middle land section, and a second outer middle-inclined groove that extends from the outer center-main groove and terminates within the outer middle land section while inclining in a direction opposite that of the first outer middle-inclined groove and being arranged alternately with the first outer middle-inclined groove, characterized in that the total number of the first and second outer middle-inclined grooves (21, 22) is set to be less than the total number of the first and second inner middle-inclined grooves (16, 17).