An interference elimination method applied to cancel interference on a k th transmitter in a wireless communication system, comprising: obtaining, by the k th transmitter, an interference vector of each receiver, wherein: the interference vector of the k th receiver is H ki w im; k, i, and m are positive integers, 1≤ k ≤ K, k≠i, 1≤ m ≤ L k, m is an index of the number of signal flows, and the number of the transmitters and the number of receivers are K; L k is the number of the signal flows of the k th receiver; H ki is a channel matrix from the i th transmitter to the k th receiver; and w im is a pre-coding vector of the i th transmitter with the index of the number of the signal flows being m; obtaining, by the k th transmitter, at least L-N linear combination relations for each receiver, wherein: the linear combination is composed of aligned interference vectors and remaining N-L k interference vectors, N is the number of receiving antennas of the receiver, and L is a sum of the signal flows of all receivers, and wherein for all receivers, an equation group is derived from the linear combination obtained, and an unknown number in the equation group is the pre-coding vectors of each transmitter; after solving the equation group, obtaining, by the k th transmitter, pre-coding vectors of all transmitters according to the linear combination relations of all receivers; and sending, by the k th transmitter, the signals pre-coded using the pre-coding vectors. obtaining, by the k th transmitter, an interference vector of each receiver, wherein: the interference vector of the k th receiver is H ki w im; k, i, and m are positive integers, 1≤ k ≤ K, k≠i, 1≤ m ≤ L k, m is an index of the number of signal flows, and the number of the transmitters and the number of receivers are K; L k is the number of the signal flows of the k th receiver; H ki is a channel matrix from the i th transmitter to the k th receiver; and w im is a pre-coding vector of the i th transmitter with the index of the number of the signal flows being m; the interference vector of the k th receiver is H ki w im; k, i, and m are positive integers, 1≤ k ≤ K, k≠i, 1≤ m ≤ L k, m is an index of the number of signal flows, and the number of the transmitters and the number of receivers are K; L k is the number of the signal flows of the k th receiver; H ki is a channel matrix from the i th transmitter to the k th receiver; and w im is a pre-coding vector of the i th transmitter with the index of the number of the signal flows being m; obtaining, by the k th transmitter, at least L-N linear combination relations for each receiver, wherein: the linear combination is composed of aligned interference vectors and remaining N-L k interference vectors, N is the number of receiving antennas of the receiver, and L is a sum of the signal flows of all receivers, and wherein for all receivers, an equation group is derived from the linear combination obtained, and an unknown number in the equation group is the pre-coding vectors of each transmitter; after solving the equation group, obtaining, by the k th transmitter, pre-coding vectors of all transmitters according to the linear combination relations of all receivers; and sending, by the k th transmitter, the signals pre-coded using the pre-coding vectors.