mhurhangee/ep-ind-claims huggingface dataset:
A traffic planning method for controlling a plurality of vehicles (v1, v2, v3, v4), wherein each vehicle occupies one node in a shared set of planning nodes (wp1, wp2, wp3, wp4, wp5, wp6, wp7, wp8) representing resources which are shared among the vehicles, and each vehicle is movable to other nodes along predefined edges between pairs of the nodes in accordance with a finite set of motion commands (v1.a1, vi.a2, v2.a1, v2.a2), the method comprising: obtaining initial node occupancies of the vehicles; and determining a sequence of motion commands by means of an optimization process configured to maximize productivity and/or minimize cost, the method characterized in that the optimization process considers a search depth (d), which corresponds to an equal number of levels of a search tree, and which is variable and determined by the following preceding steps: - from said finite set of motion commands, determining a mean number of feasible motion commands in a neighborhood of the initial node occupancies, wherein the neighborhood of the initial node occupancies corresponds to a predefined search depth ( d 0); and - determining said search depth ( d) which makes optimal use of a predefined computational budget, wherein the search depth ( d) is calculated by applying the mean number of feasible motion commands as a mean branching factor of the search tree, and the computational budget corresponds to a maximum number of leaves that a search tree may include. obtaining initial node occupancies of the vehicles; and determining a sequence of motion commands by means of an optimization process configured to maximize productivity and/or minimize cost, the method characterized in that the optimization process considers a search depth (d), which corresponds to an equal number of levels of a search tree, and which is variable and determined by the following preceding steps: - from said finite set of motion commands, determining a mean number of feasible motion commands in a neighborhood of the initial node occupancies, wherein the neighborhood of the initial node occupancies corresponds to a predefined search depth ( d 0); and - determining said search depth ( d) which makes optimal use of a predefined computational budget, wherein the search depth ( d) is calculated by applying the mean number of feasible motion commands as a mean branching factor of the search tree, and the computational budget corresponds to a maximum number of leaves that a search tree may include. - from said finite set of motion commands, determining a mean number of feasible motion commands in a neighborhood of the initial node occupancies, wherein the neighborhood of the initial node occupancies corresponds to a predefined search depth ( d 0); and - determining said search depth ( d) which makes optimal use of a predefined computational budget, wherein the search depth ( d) is calculated by applying the mean number of feasible motion commands as a mean branching factor of the search tree, and the computational budget corresponds to a maximum number of leaves that a search tree may include.
A method of preparing an output file, for use by an additive layer manufacturing machine, of a computer-generated model of a three-dimensional structure constructed of porous geometries, the method comprising: preparing a computer-generated component file including a porous computer-aided design, CAD, volume having a boundary having at least one predefined portion; populating, by a processor, a space including the porous CAD volume with unit cells overlapping the at least one predefined portion of the boundary; populating, by a processor, the unit cells with porous geometries, the porous geometries having a plurality of struts having opposing ends, each end being connected at a respective node, the plurality of struts including at least a first strut overlapping the predefined portion of the boundary, the first strut further having a length, one end connected at a first node outside the porous CAD volume, and another end connected at a second node inside the porous CAD volume; and removing all struts entirely outside the porous CAD volume such that each end of the remaining struts remains connected at its respective node; and storing the computer-generated model of the three-dimensional structure into an output file usable by an additive layer manufacturing machine in preparing the three-dimensional structure. preparing a computer-generated component file including a porous computer-aided design, CAD, volume having a boundary having at least one predefined portion; populating, by a processor, a space including the porous CAD volume with unit cells overlapping the at least one predefined portion of the boundary; populating, by a processor, the unit cells with porous geometries, the porous geometries having a plurality of struts having opposing ends, each end being connected at a respective node, the plurality of struts including at least a first strut overlapping the predefined portion of the boundary, the first strut further having a length, one end connected at a first node outside the porous CAD volume, and another end connected at a second node inside the porous CAD volume; and removing all struts entirely outside the porous CAD volume such that each end of the remaining struts remains connected at its respective node; and storing the computer-generated model of the three-dimensional structure into an output file usable by an additive layer manufacturing machine in preparing the three-dimensional structure.
A pharmaceutical composition comprising 500 mg to 650 mg amikacin or a pharmaceutically acceptable salt thereof, encapsulated in a plurality of liposomes, wherein the lipid component of the plurality of liposomes consists of dipalmitoylphosphatidylcholine (DPPC) and cholesterol for use in the treatment of a Mycobacterium avium complex lung infection, the treatment comprising: administering the pharmaceutical composition to the lungs of a patient during an administration period of at least 3 months, wherein administering the pharmaceutical composition to the lungs of the patient comprises aerosolizing the pharmaceutical composition to provide an aerosolized pharmaceutical composition comprising a mixture of free amikacin or pharmaceutically acceptable salt thereof and liposomal complexed amikacin or pharmaceutically acceptable salt thereof, and administering the aerosolized pharmaceutical composition via a nebulizer to the lungs of the patient once daily in a single dosing session during the administration period, administering to the patient one or more additional therapeutic agents selected from a macrolide antibiotic, a rifamycin, and ethambutol, and wherein the patient achieves a negative MAC sputum culture during or subsequent to the administration period. administering the pharmaceutical composition to the lungs of a patient during an administration period of at least 3 months, wherein administering the pharmaceutical composition to the lungs of the patient comprises aerosolizing the pharmaceutical composition to provide an aerosolized pharmaceutical composition comprising a mixture of free amikacin or pharmaceutically acceptable salt thereof and liposomal complexed amikacin or pharmaceutically acceptable salt thereof, and administering the aerosolized pharmaceutical composition via a nebulizer to the lungs of the patient once daily in a single dosing session during the administration period, administering to the patient one or more additional therapeutic agents selected from a macrolide antibiotic, a rifamycin, and ethambutol, and wherein the patient achieves a negative MAC sputum culture during or subsequent to the administration period.
A method of joining a pair of components, the method comprising preparing one of the components by growing an array of projections on a bond region of the component, wherein the components are joined by embedding the array of projections in the other component, characterised by each projection being grown in a series of layers by an additive fabrication process, and by each layer being grown by directing energy and/or material from a head to selected parts of the bond region.
A male fitting assembly for tubing connection, comprising: a male fitting shaped to be connected to a tube, wherein the male fitting comprises: a head including a plurality of first gripping portions, each first gripping portion extending from a top of the head; and a shaft attached to the head and comprising a plurality of external threads; a first washer configured to contact a tubing flare of the tube and distribute a force evenly around the tubing flare; an O-ring, configured to contact the first washer; characterized in that the male fitting assembly further comprises a second washer configured to contact the male fitting and the O-ring so that the male fitting rotates without moving the O-ring, wherein the O-ring is configured to (i) be located between the first washer and the second washer, and (ii) distribute the force to the first washer evenly. a male fitting shaped to be connected to a tube, wherein the male fitting comprises: a head including a plurality of first gripping portions, each first gripping portion extending from a top of the head; and a shaft attached to the head and comprising a plurality of external threads; a head including a plurality of first gripping portions, each first gripping portion extending from a top of the head; and a shaft attached to the head and comprising a plurality of external threads; a first washer configured to contact a tubing flare of the tube and distribute a force evenly around the tubing flare; an O-ring, configured to contact the first washer; characterized in that the male fitting assembly further comprises a second washer configured to contact the male fitting and the O-ring so that the male fitting rotates without moving the O-ring, wherein the O-ring is configured to (i) be located between the first washer and the second washer, and (ii) distribute the force to the first washer evenly.
An outsole for an article of footwear, the outsole comprising: a first surface of the outsole configured to be ground-facing; and a second surface of the outsole opposing the first surface, the outsole configured to be secured to an upper for an article of footwear; wherein the outsole comprises a material defining at least a portion of the first surface, and the material compositionally comprises a polymeric network formed of a plurality of polymer chains that comprise one or more hard segments; and one or more soft hydrophilic segments covalently bonded to the hard segments, wherein the one or more soft hydrophilic segments are present in the copolymer chains at a ratio ranging from 20:1 to 110:1 by weight relative to the one or more hard segments. a first surface of the outsole configured to be ground-facing; and a second surface of the outsole opposing the first surface, the outsole configured to be secured to an upper for an article of footwear; wherein the outsole comprises a material defining at least a portion of the first surface, and the material compositionally comprises a polymeric network formed of a plurality of polymer chains that comprise one or more hard segments; and one or more soft hydrophilic segments covalently bonded to the hard segments, wherein the one or more soft hydrophilic segments are present in the copolymer chains at a ratio ranging from 20:1 to 110:1 by weight relative to the one or more hard segments.
A method for forming an optical fiber preform, the method comprising: depositing silica-based glass soot on a bait rod to form a low-index trench region of the optical fiber preform, wherein the silica-based glass soot is deposited such that the low-index trench region has a first density and is initially substantially free from any dopant materials; forming a barrier layer of silica-based glass soot around the low-index trench region, wherein the barrier layer has a second density greater than the first density; depositing silica-based glass soot around the barrier layer to form an overclad region of the optical fiber preform thereby forming a trench-overclad assembly; removing the bait rod from a central channel of the trench-overclad assembly; inserting a separately formed core assembly into the central channel; and flowing a precursor gas comprising a down-dopant through the central channel of the trench-overclad assembly as the trench-overclad assembly is heated to dope the low-index trench region with the down-dopant, wherein the barrier layer prevents diffusion of the down-dopant from the low-index trench region into the overclad region. depositing silica-based glass soot on a bait rod to form a low-index trench region of the optical fiber preform, wherein the silica-based glass soot is deposited such that the low-index trench region has a first density and is initially substantially free from any dopant materials; forming a barrier layer of silica-based glass soot around the low-index trench region, wherein the barrier layer has a second density greater than the first density; depositing silica-based glass soot around the barrier layer to form an overclad region of the optical fiber preform thereby forming a trench-overclad assembly; removing the bait rod from a central channel of the trench-overclad assembly; inserting a separately formed core assembly into the central channel; and flowing a precursor gas comprising a down-dopant through the central channel of the trench-overclad assembly as the trench-overclad assembly is heated to dope the low-index trench region with the down-dopant, wherein the barrier layer prevents diffusion of the down-dopant from the low-index trench region into the overclad region.
A light-emitting device comprising: a plurality of light sources configured to be disposed on a substrate; a light diffusion member configured to commonly cover the plurality of light sources; and a plurality of wavelength conversion members configured to be disposed between the light sources and the light diffusion member in a thickness direction and disposed in regions corresponding to the plurality of light sources in a plane, respectively, and configured to convert light with a first wave-length from the light sources into light with a second wavelength, characterized by light reflection members configured to be disposed between the wavelength conversion members and the light diffusion members and disposed in regions corresponding to the plurality of light sources in the plane, respectively, and configured to reflect the light transmitted through the wave-length conversion members; wherein a central point of the light reflection member is identical to an optical axis of the light source in an in-plane direction and satisfies a condition expression and a condition expression below: Tan − 1 R 2 / L 2 < 27 ° and R 2 < R 1 where R2 is a median value of a circumradius and an inradius in the light reflection member, R1 is a radius obtained as a median value of a circumradius and an inradius in the direct upper portion of the wavelength conversion member and L2 is a distance between the light reflection member and the light diffusion member in the thickness direction. a plurality of light sources configured to be disposed on a substrate; a light diffusion member configured to commonly cover the plurality of light sources; and a plurality of wavelength conversion members configured to be disposed between the light sources and the light diffusion member in a thickness direction and disposed in regions corresponding to the plurality of light sources in a plane, respectively, and configured to convert light with a first wave-length from the light sources into light with a second wavelength, characterized by light reflection members configured to be disposed between the wavelength conversion members and the light diffusion members and disposed in regions corresponding to the plurality of light sources in the plane, respectively, and configured to reflect the light transmitted through the wave-length conversion members; wherein a central point of the light reflection member is identical to an optical axis of the light source in an in-plane direction and satisfies a condition expression and a condition expression below: Tan − 1 R 2 / L 2 < 27 ° and R 2 < R 1 where R2 is a median value of a circumradius and an inradius in the light reflection member, R1 is a radius obtained as a median value of a circumradius and an inradius in the direct upper portion of the wavelength conversion member and L2 is a distance between the light reflection member and the light diffusion member in the thickness direction.
A method for purifying a polyethylene glycol compound having one amino group and having a total average molar number of ethylene oxide units added in a molecule thereof of 20 to 2300, the method comprising the following steps, and: a step of preparing an aqueous solution of the polyethylene glycol compound having one amino group, the solution having a pH of 1 to 5, an extraction step of mixing the aqueous solution obtained in the step with a mixed organic solvent at a temperature of 10°C or higher and 55°C or lower and causing layer separation into an organic layer and an aqueous layer, wherein a ratio of an organic solvent I is 25 to 65% by mass and a ratio of an organic solvent II is 75 to 35% by mass in the mixed organic solvent, the organic solvent I is selected from an aromatic hydrocarbon-based solvent having a total carbon number of 8 or less and an ester compound solvent containing no hetero atom and having a total carbon number of 5 or less, the organic solvent II is a halogenated hydrocarbon-based solvent, and a mixing ratio Y of the organic solvent I to the organic solvent II by mass (organic solvent I/organic solvent II), temperature T (°C) at the mixing, and molecular weight M of the polyethylene glycol compound, measured by GPC under the conditions as detailed in the experimental part of the description, satisfy the following relationship: 1.9 × 10 − 6 M + 0.09 ≦ Y − 0.015 ⁢ T ≦ − 1.4 × 10 − 6 M + 0.44, and a step of recovering the polyethylene glycol compound from the aqueous layer. a step of preparing an aqueous solution of the polyethylene glycol compound having one amino group, the solution having a pH of 1 to 5, an extraction step of mixing the aqueous solution obtained in the step with a mixed organic solvent at a temperature of 10°C or higher and 55°C or lower and causing layer separation into an organic layer and an aqueous layer, wherein a ratio of an organic solvent I is 25 to 65% by mass and a ratio of an organic solvent II is 75 to 35% by mass in the mixed organic solvent, the organic solvent I is selected from an aromatic hydrocarbon-based solvent having a total carbon number of 8 or less and an ester compound solvent containing no hetero atom and having a total carbon number of 5 or less, the organic solvent II is a halogenated hydrocarbon-based solvent, and a mixing ratio Y of the organic solvent I to the organic solvent II by mass (organic solvent I/organic solvent II), temperature T (°C) at the mixing, and molecular weight M of the polyethylene glycol compound, measured by GPC under the conditions as detailed in the experimental part of the description, satisfy the following relationship: 1.9 × 10 − 6 M + 0.09 ≦ Y − 0.015 ⁢ T ≦ − 1.4 × 10 − 6 M + 0.44, and a step of recovering the polyethylene glycol compound from the aqueous layer.
A layered delivery system (100, 110) for a skin care composition, the system comprising: a. A flexible cover layer forming an upper surface of the delivery system removably attached to a coupling layer, the coupling layer having an upper surface in facing relation to the flexible cover layer, an opposite lower surface, an outer perimeter, and defining an interior void volume substantially closed by the flexible cover layer; b. A first adhesive layer coupled to the lower surface of the coupling layer through at least one intermediate layer, and disposed on a lower surface of the delivery system and protected by a removable release liner; and c. A reservoir disposed on an inner surface of the flexible cover layer, disposed in fluid communication with the interior void volume, and carrying the skin care composition. a. A flexible cover layer forming an upper surface of the delivery system removably attached to a coupling layer, the coupling layer having an upper surface in facing relation to the flexible cover layer, an opposite lower surface, an outer perimeter, and defining an interior void volume substantially closed by the flexible cover layer; b. A first adhesive layer coupled to the lower surface of the coupling layer through at least one intermediate layer, and disposed on a lower surface of the delivery system and protected by a removable release liner; and c. A reservoir disposed on an inner surface of the flexible cover layer, disposed in fluid communication with the interior void volume, and carrying the skin care composition.
A computing system that is implemented in a decentralized network that implements a distributed ledger, the distributed ledger being configured to back one or more decentralized identities, DID (210; 205), for one or more users of the computing system, the computing system comprising: one or more processors; and one or more computer-readable media having thereon computer-executable instructions that are structured such that, when executed by the one or more processors, cause the computing system to: access a DID attestation (115; 501) issued by a first entity (411; 550) of the decentralized network, the DID attestation defining information that has been generated by the first entity about a DID owner who is the subject of the DID attestation, the DID attestation including interrupt metadata that directs that the first entity be contacted prior to the DID owner being able to present the DID attestation to a second entity (401; 560) of the decentralized network; in response to the DID owner attempting to present the DID attestation to the second entity, contact the first entity as directed by the interrupt metadata; and receiving authorization information from the first entity, the authorization information indicating if the DID owner is able to present the DID attestation to the second entity. one or more processors; and one or more computer-readable media having thereon computer-executable instructions that are structured such that, when executed by the one or more processors, cause the computing system to: access a DID attestation (115; 501) issued by a first entity (411; 550) of the decentralized network, the DID attestation defining information that has been generated by the first entity about a DID owner who is the subject of the DID attestation, the DID attestation including interrupt metadata that directs that the first entity be contacted prior to the DID owner being able to present the DID attestation to a second entity (401; 560) of the decentralized network; in response to the DID owner attempting to present the DID attestation to the second entity, contact the first entity as directed by the interrupt metadata; and receiving authorization information from the first entity, the authorization information indicating if the DID owner is able to present the DID attestation to the second entity. access a DID attestation (115; 501) issued by a first entity (411; 550) of the decentralized network, the DID attestation defining information that has been generated by the first entity about a DID owner who is the subject of the DID attestation, the DID attestation including interrupt metadata that directs that the first entity be contacted prior to the DID owner being able to present the DID attestation to a second entity (401; 560) of the decentralized network; in response to the DID owner attempting to present the DID attestation to the second entity, contact the first entity as directed by the interrupt metadata; and receiving authorization information from the first entity, the authorization information indicating if the DID owner is able to present the DID attestation to the second entity.