mhurhangee/ep-ind-claims huggingface dataset:
A breathing protector to be fitted in a tracheostoma, comprising; a filter housing (100, 200, 300) with a central axis, a distal end, a proximal end, a first opening (101, 201, 301), and a second opening (102, 202, 302), wherein said second opening (102, 202, 302) is located in a proximal end of said filter housing (100, 200, 300), and said first opening (101, 201, 301) is located distally of said second opening (102, 202, 302), such that said first opening (101, 201, 301) is located upstream said second opening (102, 202, 302) during inhalation; a heat-moisture exchanging filter (103, 203, 303) received in said filter housing (100, 200, 300), wherein said heat-moisture exchanging filter (103, 203, 303) is resilient; a valve seat (105, 205, 305) around said first opening (101, 201, 301); a rail, located circumferentially of said valve seat (105, 205, 305), extending axially and distally from said first opening (101, 201, 301), said rail comprising at least one rib (106, 206, 306) extending axially and distally from said first opening (101, 201, 301) and at least one aperture (108, 208, 308) perpendicular to the central axis; a valve member (109, 209, 309), arranged in a transversal plane to the central axis, adapted to closingly engage with the valve seat (105, 205, 305) in a closed position, said valve member (109, 209, 309) being reciprocatingly arranged within said rail between the closed position and an open position; a return spring pressing the valve member (109, 209, 309) axially and distally into the open position; characterized in that the heat-moisture exchanging filter (103, 203) is the return spring, and wherein the valve member (109, 209, 309) is hindered from distal movement by the rail (106, 206) in the open position.
An in vitro method of creating a dataset of modification sites which are affected in the same way by modulators of the same protein modifying enzyme, and are therefore indicative of the activity of the protein modifying enzyme that is affected by the modulators, comprising identifying and/or quantifying modification sites on modified peptides in a first sample which has been treated with a first modulator of a protein modifying enzyme and a second sample which has been treated with a second modulator of the same protein modifying enzyme using mass spectrometry; and grouping modification sites on modified peptides from the first sample which has been treated with the first modulator of a protein modifying enzyme and modification sites on modified peptides from the second sample which has been treated with the second modulator of the same protein modifying enzyme into a single group, according to the effect of said first and second modulators of said protein modifying enzyme on said modification sites, wherein the modification sites on modified peptides from a first sample and modification sites on modified peptides from a second sample are placed into a single group based on the modification sites being affected in the same way by the first and second modulators of the protein modifying enzyme, and wherein said first and second modulators of said protein modifying enzyme are different.
Process for producing bicyclic guanidines by reacting dialkylenetriamine with dialkyl carbonate in the presence of silane of the formula Si (OR x) o R y (4-o) and/or partial hydrolysates thereof, where R x may be identical or different and are monovalent, optionally substituted hydrocarbon radicals having 2 to 10 carbon atoms, R y may be identical or different and are monovalent, optionally substituted hydrocarbon radicals having 1 to 30 carbon atoms in which individual CH 2 moieties not bonded to silicon may be replaced by oxygen or substituted by silyl groups and o is 1, 2, 3 or 4, with the proviso that, in the case of silanes of the formula where o = 4, at least two radicals R x represent a monovalent, optionally substituted hydrocarbon radical having 3 to 10 carbon atoms. R x may be identical or different and are monovalent, optionally substituted hydrocarbon radicals having 2 to 10 carbon atoms, R y may be identical or different and are monovalent, optionally substituted hydrocarbon radicals having 1 to 30 carbon atoms in which individual CH 2 moieties not bonded to silicon may be replaced by oxygen or substituted by silyl groups and o is 1, 2, 3 or 4, with the proviso that, in the case of silanes of the formula where o = 4, at least two radicals R x represent a monovalent, optionally substituted hydrocarbon radical having 3 to 10 carbon atoms.
Electronic system comprising at least one device comprising a substrate carrying at least one electronic component equipped with at least one electrical connector (121, 122), the system further comprising a support of said device, wherein the device comprises at least one passage (361, 362) according to a dimension in thickness of the device, said passage passing through at least the electrical connector (121, 122), the system comprising at least one electrically conductive pillar (471, 472) protruding over a first face of the support, the electrically conductive pillar (471, 472) passing through the passage (361, 362) by being configured to be in electrical continuity with the electrical connector (121, 122) passed through by said passage, characterised in that it comprises a casing defining a cavity for receiving the device, the support forming a bottom of the casing, the casing comprising a side wall extending from the support according to the dimension in thickness.
A coding mechanism for a cylinder lock with a rotatable key, said coding mechanism consisting of - a guiding element for aligning the shank of the rotatable key inside the cylinder lock and - the rotatable key itself, wherein the guiding element comprises two mutually parallel and spaced apart guide rails, which have their ends interconnected by an abutment bridge and which are provided with guiding surfaces extending along their entire lengths, the shank of the rotatable key being provided with usual coding projections adapted for interaction with usual catchers arranged inside the respective cylinder lock and the intermediate portion of the cross-section of the shank of the rotatable key being provided with a pair of corresponding longitudinal notches (22, 23), the longitudinal notches (22, 23) having bottom portions (24, 25), characterized in that the guiding surface of at least one guide rail and the corresponding bottom portion (24, 25) of the respective longitudinal notch (22, 23) formed in the shank of the rotatable key have their shapes adapted for generating a locking code of the cylinder lock, the shank of the rotatable key having its entire cross-section continuously increasing from its intermediate portion towards at least one of its longitudinal edges (36, 37), so that at least one of the two pairs of the functional surfaces (38, 39 and 40, 41) of said shank having an open V-shape. - a guiding element for aligning the shank of the rotatable key inside the cylinder lock and - the rotatable key itself,
A refrigeration cycle apparatus including a main refrigerant circuit, through which a refrigerant circulates through a compressor, a heat-source-side heat exchanger (3A, 3B), a first flow rate control device (4A, 4B, 4C), and a use-side heat exchanger (5A, 5B, 5C), the refrigeration cycle apparatus comprising: a first gas-liquid separator; and a foreign-substance recovery container that recovers a foreign substance contained in the refrigerant, wherein a foreign-substance recovery refrigerant circuit that connects the first gas-liquid separator with the foreign-substance recovery container through a first passage opening and closing device is arranged between a suction side of the compressor and the use-side heat exchanger (5A, 5B, 5C), in parallel with the main refrigerant circuit, and characterised in that a low-pressure-side pipe of a high-low pressure heat exchanger, a second gas-liquid separator, and a second passage opening and closing device are connected in that order between the first passage opening and closing device and the foreign-substance recovery container. a first gas-liquid separator; and a foreign-substance recovery container that recovers a foreign substance contained in the refrigerant, wherein a foreign-substance recovery refrigerant circuit that connects the first gas-liquid separator with the foreign-substance recovery container through a first passage opening and closing device is arranged between a suction side of the compressor and the use-side heat exchanger (5A, 5B, 5C), in parallel with the main refrigerant circuit, and characterised in that a low-pressure-side pipe of a high-low pressure heat exchanger, a second gas-liquid separator, and a second passage opening and closing device are connected in that order between the first passage opening and closing device and the foreign-substance recovery container.
An herbal formulation for the prevention of endothelial dysfunction Diabetes Mellitus and Diabetic Micro-Vascular complications comprising 350-550 mg Salacia chinensis, 200-400 mg Coccinia indica, 200-400 mg Hippophae rhamnoides for every 1000 mg of said formulation and optionally additives in trace amounts, in this herbal formulation, - Salacia chinensis is obtained by hydro-alcoholic extraction of root of Salacia chinensis through hot percolation method by soxhlet apparatus using water and alcohol as a solvent, the extraction being carried out continuously for 70 hours at boiling point of the solvent used; - Coccinia indica is obtained by hydro-alcoholic extraction of plant Coccinia indica with a hydro-alcoholic solvent 70:30 at the temperature of 60 to 70°C, continuously for 70 hours; - Hippophae rhamnoides is obtained by hydro-alcoholic extraction of dried fruit of Hippophae rhamnoides with a hydro-alcoholic solvent 70:30 at the temperature of 60 to 70°C, continuously for 70 hours. - Salacia chinensis is obtained by hydro-alcoholic extraction of root of Salacia chinensis through hot percolation method by soxhlet apparatus using water and alcohol as a solvent, the extraction being carried out continuously for 70 hours at boiling point of the solvent used; - Coccinia indica is obtained by hydro-alcoholic extraction of plant Coccinia indica with a hydro-alcoholic solvent 70:30 at the temperature of 60 to 70°C, continuously for 70 hours; - Hippophae rhamnoides is obtained by hydro-alcoholic extraction of dried fruit of Hippophae rhamnoides with a hydro-alcoholic solvent 70:30 at the temperature of 60 to 70°C, continuously for 70 hours.
(original) An alkoxy-functional organosiloxane oligomer of formula: where each R 1 is independently selected from the group consisting of a monovalent hydrocarbon group of 1 to 18 carbon atoms and a monovalent halogenated hydrocarbon group of 1 to 18 carbon atoms, D is a divalent hydrocarbon group of 2 to 18 carbon atoms, subscript a is an integer up to 20, subscript c is 0 or 1, and R 10 is a reactive moiety selected from the group consisting of where R 4, R 5, R 6, R 7, R 8 and R 9 are each independently selected from the group consisting of a monovalent hydrocarbon group of 1 to 18 carbon atoms and a monovalent halogenated hydrocarbon group of 1 to 18 carbon atoms.
A tin oxide-based electrode formed from a composition comprising: a major component comprised of SnO 2, wherein the SnO 2 forms not less than 95 wt% of the composition; additives comprising a=CuO, b=ZnO, and c=Sb 2 O 3, wherein a, b, and c represent weight percentages of respective components CuO, ZnO and Sb 2 O 3, wherein the relationship of components a, b and c is 0.2 ≤ (a + b)/c < 0.9 and the relationship of components a and b is 0.05 < a/b < 0.7, CuO being present in an amount of not less than 0.025 wt% of the composition, ZnO being present within a range of 0.25 to 0.975 wt% of the composition, and Sb 2 O 3 being present within a range of 0.50 to 1.5 wt% of the composition. a major component comprised of SnO 2, wherein the SnO 2 forms not less than 95 wt% of the composition; additives comprising a=CuO, b=ZnO, and c=Sb 2 O 3, wherein a, b, and c represent weight percentages of respective components CuO, ZnO and Sb 2 O 3, wherein the relationship of components a, b and c is 0.2 ≤ (a + b)/c < 0.9 and the relationship of components a and b is 0.05 < a/b < 0.7, CuO being present in an amount of not less than 0.025 wt% of the composition, ZnO being present within a range of 0.25 to 0.975 wt% of the composition, and Sb 2 O 3 being present within a range of 0.50 to 1.5 wt% of the composition.
A door opener with a monitoring system, comprising: - a bolt assembled on a rotating shaft; - a height adjustable front part with respect to the bolt, said adjustable front part being movable between a lower position and an upper position away from the rotating shaft of the bolt, and being provided with a stop defining a lower plane for retaining a catch of a door in a closed position; - an internal mechanism for locking and unlocking the bolt activating a solenoid and, - a drive cam of a monitoring system for monitoring the state of the door, said cam facing the front part of the bolt and being moved by the catch of the door from an inoperative position to an operative position in which said cam drives the monitoring system by providing a signal about the closed state of the door; - wherein the adjustable front part comprises a receiving groove of the cam, said groove being defined both on a front face and in the stop of said front part; characterised in that: - the cam and the adjustable front part are sized such that, when the front part is in said lower position, an end of the cam is arranged inside the groove of the stop of the front part, and when the front part is in said upper position, the end of the cam is arranged considerably flush with said lower plane of the stop or inside the groove of the stop. - a bolt assembled on a rotating shaft; - a height adjustable front part with respect to the bolt, said adjustable front part being movable between a lower position and an upper position away from the rotating shaft of the bolt, and being provided with a stop defining a lower plane for retaining a catch of a door in a closed position; - an internal mechanism for locking and unlocking the bolt activating a solenoid and, - a drive cam of a monitoring system for monitoring the state of the door, said cam facing the front part of the bolt and being moved by the catch of the door from an inoperative position to an operative position in which said cam drives the monitoring system by providing a signal about the closed state of the door; - wherein the adjustable front part comprises a receiving groove of the cam, said groove being defined both on a front face and in the stop of said front part; - the cam and the adjustable front part are sized such that, when the front part is in said lower position, an end of the cam is arranged inside the groove of the stop of the front part, and when the front part is in said upper position, the end of the cam is arranged considerably flush with said lower plane of the stop or inside the groove of the stop.
An additive manufacturing device comprising: a molding unit including a molding tank accommodating a manufactured object and forming the manufactured object in the molding tank; a pressure vessel accommodating the molding unit; and a gas supply unit connected to the pressure vessel, supplying a gas into the pressure vessel, and configured to pressurize an inner portion of the pressure vessel, wherein a hole portion allowing an inside and an outside of a wall portion of the molding tank to communicate with each other is provided in the wall portion, and wherein the molding tank is configured such that the hole portion remains closed during the molding of the manufactured object and the hole portion opens after the molding of the manufactured object to allow the gas in the pressure vessel to flow through the hole portion into the molding tank. a molding unit including a molding tank accommodating a manufactured object and forming the manufactured object in the molding tank; a pressure vessel accommodating the molding unit; and a gas supply unit connected to the pressure vessel, supplying a gas into the pressure vessel, and configured to pressurize an inner portion of the pressure vessel, wherein a hole portion allowing an inside and an outside of a wall portion of the molding tank to communicate with each other is provided in the wall portion, and wherein the molding tank is configured such that the hole portion remains closed during the molding of the manufactured object and the hole portion opens after the molding of the manufactured object to allow the gas in the pressure vessel to flow through the hole portion into the molding tank.
A drive apparatus for a reciprocating tool (10, 100), comprising; a housing; a rotatable drive shaft assembly (34, 36, 38, 40) located in said housing; an elongated spindle (28, 28' 28") located in said housing for reciprocating motion, said spindle having a front end portion for attaching a cutting blade thereto and a rear portion; a bushing in said housing for supporting said spindle; and a wobble drive mechanism comprising a wobble drive shaft connected to said drive shaft assembly, an elongated arm having a lengthwise axis extending upwardly from said wobble drive shaft and including an upper interface for reciprocating said spindle generally in its lengthwise direction during alternating cutting and return strokes; wherein said upper interface connects said arm to said spindle in a manner that prevents translational movement of said spindle relative to said arm in the direction of the arm lengthwise axis and causes a cutting blade attached to said front end portion to travel through an arc-like path that is traversed in said cutting and return strokes; characterized in that said upper interface comprises an adapter that is configured to be connected to said arm and said spindle by first and second pivot connections at opposite end portions, said pivot connections being oriented perpendicular to one another, said first connection between said adapter and said arm permitting side to side pivoting movement of said spindle, and said second connection between said adapter and said spindle permitting reciprocating movement of said spindle in its lengthwise direction, wherein said bushing is a front bushing for supporting the front end portion of said spindle and said front bushing permits reciprocating and limited angular motion of said spindle therein; wherein said arm has an upper end portion with a recess configured to receive said adapter, said adapter having a generally cylindrical shape with a lengthwise axis and being sized to fit within said recess and be pivotable in two orthogonal directions relative to said arm; wherein said first pivot connection comprises a first pin interconnecting said adapter and said arm, said first pin being oriented generally in the lengthwise direction of said spindle to thereby permit said side to side pivoting movement of said spindle; wherein said second pivot connection comprises a second pin interconnecting said adapter and said spindle, said second pin being oriented perpendicular to the lengthwise axis of said adapter and perpendicular to said first pin.
A vessel bottom cover configured to be attached to a bottom part of a vessel standardized as for use in dissolution tests, the vessel having a cylindrical body and a hemispherical bottom part, wherein the vessel bottom cover has a column body with a recessed portion in a top face of the column body, and the recessed portion is configured to be fitted with the hemispherical bottom part of the vessel having the hemispherical bottom part and the cylindrical body of: - 160 to 210 mm in height and 98 to 106 mm in inside diameter, - 280 to 300 mm in height and 98 to 106 mm in inside diameter, or - 280 to 300 mm in height and 145 to 155 mm in inside diameter, and the vessel bottom cover is made of a transparent resin or a transparent inorganic material, wherein the bottom face of the vessel bottom cover is flat or provided with a recessed portion, characterised in that the side face of the column body has a convex curve shape. - 160 to 210 mm in height and 98 to 106 mm in inside diameter, - 280 to 300 mm in height and 98 to 106 mm in inside diameter, or - 280 to 300 mm in height and 145 to 155 mm in inside diameter,
A process for preparing a modified zeolite Y which process comprises subjecting zeolite Y having a silica to alumina molar ratio of at least 10 and a unit cell size less than 24.40 Å to calcination at a temperature of from 700 to 1000 °C wherein (i) the steam partial pressure is at most 0.06 bar at a temperature of from 700 to 800 °C, (ii) the steam partial pressure is at most 0.08 bar at a temperature of from greater than 800 to 850 °C, (iii) the steam partial pressure is at least 0.03 bar at a temperature of 850 to less than 900 °C, and (iv) the steam partial pressure is at least 0.05 bar at a temperature of from 900 to less than 950 °C and (v) the steam partial pressure is at least 0.07 bar at a temperature of from 950 to 1000 °C.
Method for selecting a eukaryotic cell expressing an immunoglobulin, whereby the method comprises a) transfecting a eukaryotic cell with a nucleic acid comprising in 5' to 3' direction i) a first nucleic acid encoding at least a fragment of an immunoglobulin heavy chain C H 3 or C H 4 domain without an in frame translational stop codon, ii) a second nucleic acid beginning with the 5' splice donor site of an immunoglobulin heavy chain C H 3 or C H 4 domain exon and terminated by the 3' splice acceptor site of the succeeding immunoglobulin heavy chain transmembrane domain exon M1 comprising an in frame translational stop codon and a polyadenylation signal, iii) a third nucleic acid encoding iiia) at least a fragment of an immunoglobulin transmembrane domain, b) culturing of said transfected cell under conditions suitable for the production of pre-mRNA from said nucleic acid, processing of said pre-mRNA, and translation of said processed mRNA into an immunoglobulin, wherein said transfected cell produces soluble immunoglobulin and plasma-membrane-bound immunoglobulin by alternative splicing of said pre-mRNA, and c) selecting a cell with plasma-membrane-bound immunoglobulin to be said cell expressing an immunoglobulin. a) transfecting a eukaryotic cell with a nucleic acid comprising in 5' to 3' direction i) a first nucleic acid encoding at least a fragment of an immunoglobulin heavy chain C H 3 or C H 4 domain without an in frame translational stop codon, ii) a second nucleic acid beginning with the 5' splice donor site of an immunoglobulin heavy chain C H 3 or C H 4 domain exon and terminated by the 3' splice acceptor site of the succeeding immunoglobulin heavy chain transmembrane domain exon M1 comprising an in frame translational stop codon and a polyadenylation signal, iii) a third nucleic acid encoding iiia) at least a fragment of an immunoglobulin transmembrane domain, i) a first nucleic acid encoding at least a fragment of an immunoglobulin heavy chain C H 3 or C H 4 domain without an in frame translational stop codon, ii) a second nucleic acid beginning with the 5' splice donor site of an immunoglobulin heavy chain C H 3 or C H 4 domain exon and terminated by the 3' splice acceptor site of the succeeding immunoglobulin heavy chain transmembrane domain exon M1 comprising an in frame translational stop codon and a polyadenylation signal, iii) a third nucleic acid encoding iiia) at least a fragment of an immunoglobulin transmembrane domain, iiia) at least a fragment of an immunoglobulin transmembrane domain, b) culturing of said transfected cell under conditions suitable for the production of pre-mRNA from said nucleic acid, processing of said pre-mRNA, and translation of said processed mRNA into an immunoglobulin, wherein said transfected cell produces soluble immunoglobulin and plasma-membrane-bound immunoglobulin by alternative splicing of said pre-mRNA, and c) selecting a cell with plasma-membrane-bound immunoglobulin to be said cell expressing an immunoglobulin.