mhurhangee/ep-ind-claims huggingface dataset:
A magnetic field sensor, comprising: a circular vertical Hall sensing element comprising a plurality of individual vertical Hall elements, each vertical Hall element comprised of a respective group of vertical Hall element contacts selected from among a plurality of vertical Hall element contacts, the plurality of vertical Hall element contacts arranged over a common implant region in a semiconductor substrate, adjacent ones of the plurality of contacts at predetermined angles from each other; a CVH output stage comprising a drive circuit configured to drive the plurality of vertical Hall elements and produce an analog signal representing a strength of an external magnetic field as detected by the plurality of vertical Hall elements, the analog signal made up of outputs from the individual vertical Hall elements taken sequentially; an analog-to-digital converter coupled to receive the analog signal and produce a digital signal; a quadrature modulator circuit coupled to the digital signal and operable to generate from the digital signal a plurality of quadrature modulated signals; and a processor stage coupled to receive signals representative of the plurality of quadrature modulated signals and operable to compute an estimated angle of the external magnetic field using the received signals. a circular vertical Hall sensing element comprising a plurality of individual vertical Hall elements, each vertical Hall element comprised of a respective group of vertical Hall element contacts selected from among a plurality of vertical Hall element contacts, the plurality of vertical Hall element contacts arranged over a common implant region in a semiconductor substrate, adjacent ones of the plurality of contacts at predetermined angles from each other; a CVH output stage comprising a drive circuit configured to drive the plurality of vertical Hall elements and produce an analog signal representing a strength of an external magnetic field as detected by the plurality of vertical Hall elements, the analog signal made up of outputs from the individual vertical Hall elements taken sequentially; an analog-to-digital converter coupled to receive the analog signal and produce a digital signal; a quadrature modulator circuit coupled to the digital signal and operable to generate from the digital signal a plurality of quadrature modulated signals; and a processor stage coupled to receive signals representative of the plurality of quadrature modulated signals and operable to compute an estimated angle of the external magnetic field using the received signals.
Method for producing alkoxybenzonitriles according to formula where, for the functional groups Y and R 5, simultaneously or independently of one another, R 5 = hydrogen, hydroxy or a functional group according to formula where p = a number from 0 to 4 Y = hydrogen, fluorine, chlorine, bromine or iodine; and where, for the functional groups R 1, R 2, R 3, R 4 and the values m, n, o, simultaneously or independently of one another: a) R 1, R 2, R 3, R 4 = simultaneously or independently of one another hydrogen, hydroxy, C1-C6 alkyl, C1-C6 hydroxyalkyl or a functional group according to formula and meaning indicated above; m = a number from 1 to 4; n, o = simultaneously or independently of one another a number from 0 to 4; or b) R 1 and R 2 = together forming a ring, C1-C6 alkylene or C1-C6 hydroxyalkylene; R 3, R 4 = simultaneously or independently of one another hydrogen, hydroxy, C1-C6 alkyl, C1-C6 hydroxyalkyl or a functional group according to formula and meaning indicated above; m, n = simultaneously or independently of one another a number from 1 to 4; o = a number from 0 to 4; or c) R 1 and R 4 = together forming a ring, C1-C6 alkylene or C1-C6 hydroxyalkylene; R 2, R 3 = simultaneously or independently of one another hydrogen, hydroxy, C1-C6 alkyl, C1-C6 hydroxyalkyl or a functional group according to formula and meaning indicated above; m, o = simultaneously or independently of one another a number from 1 to 4; n = a number from 0 to 4; in which a halogen benzonitrile according to formula is reacted with an alcohol according to formula: where the functional groups R 1, R 2, R 3, R 4, R 5, Y and the values m, n, o have the meaning indicated above, and for the functional group X: X = fluorine, chlorine, bromine or iodine; characterised in that the reaction in a polar aprotic solvent that is different from dimethyl sulfoxide is carried out in the presence of sodium methylsulfinylmethylide, the polar aprotic solvent having a permittivity of more than 15. R 5 = hydrogen, hydroxy or a functional group according to formula where p = a number from 0 to 4 Y = hydrogen, fluorine, chlorine, bromine or iodine; a) R 1, R 2, R 3, R 4 = simultaneously or independently of one another hydrogen, hydroxy, C1-C6 alkyl, C1-C6 hydroxyalkyl or a functional group according to formula and meaning indicated above; m = a number from 1 to 4; n, o = simultaneously or independently of one another a number from 0 to 4; or b) R 1 and R 2 = together forming a ring, C1-C6 alkylene or C1-C6 hydroxyalkylene; R 3, R 4 = simultaneously or independently of one another hydrogen, hydroxy, C1-C6 alkyl, C1-C6 hydroxyalkyl or a functional group according to formula and meaning indicated above; m, n = simultaneously or independently of one another a number from 1 to 4; o = a number from 0 to 4; or c) R 1 and R 4 = together forming a ring, C1-C6 alkylene or C1-C6 hydroxyalkylene; R 2, R 3 = simultaneously or independently of one another hydrogen, hydroxy, C1-C6 alkyl, C1-C6 hydroxyalkyl or a functional group according to formula and meaning indicated above; m, o = simultaneously or independently of one another a number from 1 to 4; n = a number from 0 to 4;
A pharmaceutical composition comprising a population of lung spheroid cell-derived exosomes in an amount effective in modulating a pulmonary pathological condition when delivered to an animal or human subject in need thereof, and a pharmaceutically acceptable carrier.
Process for the biocatalytic preparation of sphingolipids of the general formula I by preparing a lysosphingolipid of the general formula II by deprotonation of an acid addition product, and reacting the lysosphingolipid with a carboxylic ester of the general formula III where R 1 represents a linear or branched alkyl chain which has 2 to 55 carbon atoms, optionally comprises one or more multiple bonds and/or aromatic or heteroaromatic rings, is optionally interrupted by oxygen atoms or ester or amide functionalities and is optionally substituted by at least one further group selected from alkyl, hydroxy, keto or amine groups, R 2 represents H, phosphocholine, ethanolamine, serine or a sugar, X represents CH=CH, CH 2 -CH 2 or CH 2 -HCOH, R 3 represents a branched or unbranched alkyl radical which has 1 to 12 carbon atoms and may be substituted with at least one radical -OR 4, where R 4 independently is identical or nonidentical radicals selected from the group comprising H and -C R 1 where R 1 is as defined above, characterized in that a biocatalyst used includes at least one carboxylic ester hydrolase of enzyme class E.C. 3.1.1 selected from the group comprising carboxylic ester hydrolases of enzyme class E.C. 3.1.1 which can be isolated from an organism of the kingdom of fungi and carboxylic ester hydrolases of enzyme class E.C. 3.1.1 which are at least 80% homologous at the amino acid level with those which can be isolated from one organism of the kingdom of fungi, and in that an organic or inorganic base which does not liberate any water after protonation is employed for the deprotonation. where R 1 represents a linear or branched alkyl chain which has 2 to 55 carbon atoms, optionally comprises one or more multiple bonds and/or aromatic or heteroaromatic rings, is optionally interrupted by oxygen atoms or ester or amide functionalities and is optionally substituted by at least one further group selected from alkyl, hydroxy, keto or amine groups, R 2 represents H, phosphocholine, ethanolamine, serine or a sugar, X represents CH=CH, CH 2 -CH 2 or CH 2 -HCOH, R 3 represents a branched or unbranched alkyl radical which has 1 to 12 carbon atoms and may be substituted with at least one radical -OR 4, where R 4 independently is identical or nonidentical radicals selected from the group comprising H and -C R 1 where R 1 is as defined above, characterized in that a biocatalyst used includes at least one carboxylic ester hydrolase of enzyme class E.C. 3.1.1 selected from the group comprising carboxylic ester hydrolases of enzyme class E.C. 3.1.1 which can be isolated from an organism of the kingdom of fungi and carboxylic ester hydrolases of enzyme class E.C. 3.1.1 which are at least 80% homologous at the amino acid level with those which can be isolated from one organism of the kingdom of fungi, and in that an organic or inorganic base which does not liberate any water after protonation is employed for the deprotonation.
An ophthalmic imaging probe, comprising: a handle; a cannula coupled to the handle, the cannula sized and shaped for insertion through a sclera of an eye to facilitate imaging of a retina of the eye; an optical fiber positioned at least partially within the handle and the cannula, the optical fiber having an electrically conductive layer, the optical fiber configured to receive an imaging light from an imaging light source and guide the imaging light to an optical element positioned within the distal portion of the cannula; and an actuator system configured to impart motion to the optical fiber, the actuator system including an electrode (194, 196, 232, 242, 262, 272, 282, 302, 312, 322, 332) positioned within the cannula and configured to impart motion to the optical fiber by selectively imparting an electric charge to at least one of the electrode and the electrically conductive layer of the optical fiber. a handle; a cannula coupled to the handle, the cannula sized and shaped for insertion through a sclera of an eye to facilitate imaging of a retina of the eye; an optical fiber positioned at least partially within the handle and the cannula, the optical fiber having an electrically conductive layer, the optical fiber configured to receive an imaging light from an imaging light source and guide the imaging light to an optical element positioned within the distal portion of the cannula; and an actuator system configured to impart motion to the optical fiber, the actuator system including an electrode (194, 196, 232, 242, 262, 272, 282, 302, 312, 322, 332) positioned within the cannula and configured to impart motion to the optical fiber by selectively imparting an electric charge to at least one of the electrode and the electrically conductive layer of the optical fiber.
Use of a liquid composition, comprising - one or more monomers for the production of a polyester, polyamide or polyesteramide, where at least one monomer is at least trifunctional, - a solvent, as binder, which when hardened leads to a polyester, polyamide or polyesteramide, in additive manufacture by binder jetting. - one or more monomers for the production of a polyester, polyamide or polyesteramide, where at least one monomer is at least trifunctional, - a solvent,
A laminate comprising a support, a resin layer formed on the support, a metal layer formed on the resin layer, an insulating layer and a redistribution layer formed on the metal layer, the resin layer comprising a photo-decomposable resin having light-shielding properties and having a transmittance of up to 20% with respect to light of wavelength 355 nm, measured according to the method specified in the description, wherein the resin layer is formed of a cured product of a resin composition comprising a resin comprising repeating units having the formula: wherein R 1 to R 3 are each independently hydrogen, hydroxyl or a C 1 -C 20 monovalent organic group, at least one of R 1 to R 3 being hydroxyl, and R 4 is hydrogen or an optionally substituted C 1 -C 30 monovalent organic group.
A polyimide resin, which is an imidized product of polyamic acid in which a polymerization composition comprising diamine-based monomers and dianhydride-based monomers is copolymerized, wherein the diamine-based monomers comprise: bis(trifluoromethyl)-I,I'-biphenyl-4,4'-diamine (TFDB); and at least one selected from among 1,3-bis(4-aminophenoxy)benzene and 2,2-bis[4-(4-aminophenoxy)phenyl]hexafluoropropane (4BDAF), the dianhydride-based monomers comprise any mixture of 4,4'-hexafluoroisopropylidene diphthalic anhydride, 3,3,4,4-diphenylsulfonetetracarboxylic dianhydride (SO 2 DPA) and/or oxydiphthalic dianhydride (ODPA), and wherein the at least one selected from among 1,3-bis(4-aminophenoxy)benzene and 2,2-bis[4-(4-aminophenoxy)phenyl]hexafluoropropane (4BDAF) is used in an amount of 10 mol% or less based on a total molar amount of the diamine-based monomer. wherein the diamine-based monomers comprise: bis(trifluoromethyl)-I,I'-biphenyl-4,4'-diamine (TFDB); and at least one selected from among 1,3-bis(4-aminophenoxy)benzene and 2,2-bis[4-(4-aminophenoxy)phenyl]hexafluoropropane (4BDAF), bis(trifluoromethyl)-I,I'-biphenyl-4,4'-diamine (TFDB); and at least one selected from among 1,3-bis(4-aminophenoxy)benzene and 2,2-bis[4-(4-aminophenoxy)phenyl]hexafluoropropane (4BDAF), the dianhydride-based monomers comprise any mixture of 4,4'-hexafluoroisopropylidene diphthalic anhydride, 3,3,4,4-diphenylsulfonetetracarboxylic dianhydride (SO 2 DPA) and/or oxydiphthalic dianhydride (ODPA), and wherein the at least one selected from among 1,3-bis(4-aminophenoxy)benzene and 2,2-bis[4-(4-aminophenoxy)phenyl]hexafluoropropane (4BDAF) is used in an amount of 10 mol% or less based on a total molar amount of the diamine-based monomer.
A method of improving the removal efficiency of a color cosmetic, comprising applying a makeup base cosmetic composition for skin containing biocellulose microfibrils to the skin before applying the color cosmetic, wherein the biocellulose microfibrils have a number-average diameter of 30 to 60 nm and a maximum diameter of 60 to 100 nm, and wherein the cosmetic composition further comprises a polyvinyl alcohol-based film-forming polymer. wherein the biocellulose microfibrils have a number-average diameter of 30 to 60 nm and a maximum diameter of 60 to 100 nm, and wherein the cosmetic composition further comprises a polyvinyl alcohol-based film-forming polymer.
A Cardio-Pulmonary Resuscitation ("CPR") machine configured to perform chest compressions on a chest of a patient, the chest having a resting height relative to a reference level, the resting height measured when no chest compressions are being performed, the CPR machine comprising: a compression mechanism; a chest-lifting device configured to lift the chest; a driver system configured to drive the compression mechanism and the chest-lifting device according to a motion-time profile (1800,1900, 2000) so as to cause the compression mechanism to repeatedly perform the chest compressions, the driver further configured to drive the chest-lifting device according to the motion-time profile and to cause the chest-lifting device to lift the chest to a height above the reference level; and a failure detector configured to detect if the chest-lifting device fails to lift the chest: and in which the motion-time profile is configured to be adjusted in response to the failure detector detecting that the chest-lifting device failed to lift the chest. a compression mechanism; a chest-lifting device configured to lift the chest; a driver system configured to drive the compression mechanism and the chest-lifting device according to a motion-time profile (1800,1900, 2000) so as to cause the compression mechanism to repeatedly perform the chest compressions, the driver further configured to drive the chest-lifting device according to the motion-time profile and to cause the chest-lifting device to lift the chest to a height above the reference level; and a failure detector configured to detect if the chest-lifting device fails to lift the chest: and in which the motion-time profile is configured to be adjusted in response to the failure detector detecting that the chest-lifting device failed to lift the chest.
A light apparatus selectively operable as a torchlight and a nightlight 1, said apparatus including a housing 3 and having a first end with a substantially transparent portion 11, and side walls 13 which, at least in part, are at least partially transparent to allow light to pass to externally of the apparatus 1; one or more light sources 23 located within the housing such as to cause, when illuminated, illumination within the housing 3 characterised in that said apparatus 1 further includes motion sensing means 5, and said one or more light sources 23 are illuminated upon detection by said motion sensing means 5 of movement of the apparatus 1 and said one or more light sources cease to illuminate after a predetermined period of non-movement of the apparatus 1 and when the first end 11 of the housing 3 is unblocked the illumination passes through the same to cause the apparatus 1 to operate as a torchlight and when the said first end 11 is blocked the apparatus 1 operates as a nightlight by the increase in prominence of the illumination from the same one or more light sources 23 passing through the partially transparent side walls 13 of the housing 3.
A seatbelt retractor having a switchable force-limiting device for a seatbelt of a motor vehicle including: - a belt shaft and a locking device locking the belt shaft in the belt extraction direction upon an activation, wherein the force-limiting device is disposed in the force flow between the belt shaft and the locking device, and - a switching device for switching the force-limiting device, which force-limiting device includes a gas generator for releasing a gas flow into a pressure chamber and a piston activatable by the gas flow, characterised in that - the piston is disposed on an expandable, hollow pot that is connected gas-tight to the gas generator and forms the pressure chamber. - a belt shaft and a locking device locking the belt shaft in the belt extraction direction upon an activation, wherein the force-limiting device is disposed in the force flow between the belt shaft and the locking device, and - a switching device for switching the force-limiting device, which force-limiting device includes a gas generator for releasing a gas flow into a pressure chamber and a piston activatable by the gas flow, characterised in that - the piston is disposed on an expandable, hollow pot that is connected gas-tight to the gas generator and forms the pressure chamber.
A device configured to monitor traffic of a network, the device comprising a memory configured to record, for each flow in the network, metadata and flow information to be used in measurement, and a traffic feature value calculation unit configured to forecast a future traffic state, wherein the traffic state is forecasted using a packet flowing in the network; wherein the memory comprises a recording area for the metadata and the flow information, which is configured to be set based on the forecasted traffic state, wherein the recording area is a hash table configured to store and update key-value pairs, wherein flow information is recorded and updated by using the hash table with a flow as a key and a counter as a value. a memory configured to record, for each flow in the network, metadata and flow information to be used in measurement, and a traffic feature value calculation unit configured to forecast a future traffic state, wherein the traffic state is forecasted using a packet flowing in the network; wherein the memory comprises a recording area for the metadata and the flow information, which is configured to be set based on the forecasted traffic state, wherein the recording area is a hash table configured to store and update key-value pairs, wherein flow information is recorded and updated by using the hash table with a flow as a key and a counter as a value.
A valve prosthesis for implantation into a native cardiac valve site of an individual, the valve prosthesis comprising: a valve body; and a frame supporting the valve body, the frame comprising: a central portion configured to fit securely within an annulus of the valve site; a support arm extending from the central portion of the frame and configured to extend over and secure a native valve leaflet; an inlet portion configured to engage the floor of the outflow tract of the native heart atrium and restrict movement of the valve prosthesis in a downstream direction of blood flow at the valve site; wherein the inlet portion includes an extension that protrudes in a radially outward direction from the central portion of the frame, wherein the inlet portion is substantially s-shaped, wherein the s-shape of the inlet portion is formed by the extension bending in a first curve from an inflow end of the frame towards an outflow end of the frame and then bending in a second curve back towards the inflow end. a valve body; and a frame supporting the valve body, the frame comprising: a central portion configured to fit securely within an annulus of the valve site; a support arm extending from the central portion of the frame and configured to extend over and secure a native valve leaflet; an inlet portion configured to engage the floor of the outflow tract of the native heart atrium and restrict movement of the valve prosthesis in a downstream direction of blood flow at the valve site; wherein the inlet portion includes an extension that protrudes in a radially outward direction from the central portion of the frame, wherein the inlet portion is substantially s-shaped, wherein the s-shape of the inlet portion is formed by the extension bending in a first curve from an inflow end of the frame towards an outflow end of the frame and then bending in a second curve back towards the inflow end. a central portion configured to fit securely within an annulus of the valve site; a support arm extending from the central portion of the frame and configured to extend over and secure a native valve leaflet; an inlet portion configured to engage the floor of the outflow tract of the native heart atrium and restrict movement of the valve prosthesis in a downstream direction of blood flow at the valve site; wherein the inlet portion includes an extension that protrudes in a radially outward direction from the central portion of the frame, wherein the inlet portion is substantially s-shaped, wherein the s-shape of the inlet portion is formed by the extension bending in a first curve from an inflow end of the frame towards an outflow end of the frame and then bending in a second curve back towards the inflow end.