mhurhangee/ep-ind-claims huggingface dataset:
A tamper-evident closure for a container neck, the tamper-evident closure comprising: a first portion (105, 106), and a second portion (102, 104) comprising a window through which a view of the first portion (105, 106) is visible; the second portion (102, 104) rotatable relative to the first portion (105, 106) upon first opening of the tamper-evident closure, in a first direction of rotation, from a first position in which the first and second portions (105, 106; 102, 104) are in a first relative relation to a second position in which the first and second portions (105, 106; 102, 104) are in a second relative relation; and rotation of the second portion (102, 104) relative to the first portion (105, 106) causes rotation of the window relative to the first portion (105, 106), a first view of the first portion (105, 106) is visible through the window when the first and second portions (105, 106; 102, 104) are in the first relative relation, and a second, different view of the first portion (105, 106) is visible through the window when the first and second portions (105, 106; 102, 104) are in the second relative relation; characterized in that the closure further comprises a locking mechanism for irreversibly locking the first and second portions (105, 106; 102, 104) in the second relative relation; whereby the view of the first portion (105, 106) through the window of the second portion (102, 104) is irreversibly changed during first opening of the tamper-evident closure. a first portion (105, 106), and a second portion (102, 104) comprising a window through which a view of the first portion (105, 106) is visible; the second portion (102, 104) rotatable relative to the first portion (105, 106) upon first opening of the tamper-evident closure, in a first direction of rotation, from a first position in which the first and second portions (105, 106; 102, 104) are in a first relative relation to a second position in which the first and second portions (105, 106; 102, 104) are in a second relative relation; and rotation of the second portion (102, 104) relative to the first portion (105, 106) causes rotation of the window relative to the first portion (105, 106), a first view of the first portion (105, 106) is visible through the window when the first and second portions (105, 106; 102, 104) are in the first relative relation, and a second, different view of the first portion (105, 106) is visible through the window when the first and second portions (105, 106; 102, 104) are in the second relative relation; characterized in that the closure further comprises a locking mechanism for irreversibly locking the first and second portions (105, 106; 102, 104) in the second relative relation; whereby the view of the first portion (105, 106) through the window of the second portion (102, 104) is irreversibly changed during first opening of the tamper-evident closure.
A positioning method for balloon coating for forming a coating layer containing a water-insoluble drug on an outer surface of a balloon of a balloon catheter, wherein a flexible dispensing tube is formed with an opening portion for discharging a coating solution containing the water-insoluble drug and a solvent, and a plane which is perpendicular to an extending direction of the dispensing tube in a state of non-contact with the balloon and which passes through an axis of the balloon is defined as a reference plane, and the positioning method comprises a positioning step in which the dispensing tube is positioned relative to the balloon in such a manner that a virtual position at which the opening portion would be located if the dispensing tube is assumed to be non-flexible is located at a position deviated from the reference plane toward the balloon rotating direction side by an angle (θ) within the range of 0 degrees to 40 degrees, with the axis of the balloon (x) as the vertex of the angle, in a region extending from the reference plane in a direction opposite to a discharge direction of the dispensing tube, wherein in the positioning step, the dispensing tube is moved in the extending direction of the dispensing tube without making contact with the balloon, after which the dispensing tube is moved in a direction intersecting the extending direction of the dispensing tube, and an opening portion-formed end portion side of the dispensing tube formed with the opening portion at its end portion is thereby placed in contact with the outer surface of the balloon; or the coating solution is discharged in a state where a continuous length of a side surface on an opening portion-formed end portion side of the dispensing tube is kept in contact with the outer surface of the balloon; and wherein in a contact step in or, the flexible dispensing tube is pressed against the outer surface of the balloon while being bent. in the positioning step, the dispensing tube is moved in the extending direction of the dispensing tube without making contact with the balloon, after which the dispensing tube is moved in a direction intersecting the extending direction of the dispensing tube, and an opening portion-formed end portion side of the dispensing tube formed with the opening portion at its end portion is thereby placed in contact with the outer surface of the balloon; or the coating solution is discharged in a state where a continuous length of a side surface on an opening portion-formed end portion side of the dispensing tube is kept in contact with the outer surface of the balloon; and wherein in a contact step in or, the flexible dispensing tube is pressed against the outer surface of the balloon while being bent.
A non-particulate cross-linked poly-ε-lysine polymer comprising poly-ε-lysine and a cross linker linked by amide bonds wherein the polymer is cross-linked with a cross linker comprising two or more carboxylic acid groups and an aliphatic chain linking the two or more groups reacting with an alpha carbon amine of poly-ε-lysine.
Device comprising a catheter for intravascular use, the catheter having a blood inlet and a blood outlet and comprising a membrane, a first side of the membrane delimiting a lumen for receiving a carrier medium and the membrane being arranged in the catheter such that at least a portion of the blood flowing through the blood inlet into the catheter during operation comes into contact with a second side of the membrane, opposite the first side, before the blood exits the catheter through the blood outlet, the membrane permitting an exchange of at least one substance to be exchanged between a carrier medium received in the lumen during operation and the blood, and the catheter comprising a conveying device having a drive unit for generating a torque and having a pump rotor connected to the drive unit for transmitting a torque, the conveying device being set up to at least partially compensate for a pressure difference between the blood inlet and the blood outlet during operation, and the membrane being a membrane suitable for liquids, the carrier medium being a carrier liquid in which the substance to be exchanged is soluble, and characterised in that the pump rotor is connected to the drive unit by a magnetic coupling, the magnetic coupling comprising two coupling parts (88, 101) which can be rotated relative to one another along a rotational axis and which each have a permanent magnet (103, 102), one of the coupling parts comprising an at least partially ferromagnetic deflection element which is connected to the permanent magnet of the coupling part for conjoint rotation therewith, part of the deflection element being arranged radially outside the permanent magnet of the other coupling part, the deflection element having at least one diamagnetic separating means which divides the deflection element into at least two ferromagnetic portions.
Process for making a particulate (oxy)hydroxide or oxide of TM wherein TM represents one or more metals, and wherein TM comprises nickel or cobalt and, optionally, at least one metal selected from aluminum and manganese, wherein said process comprises the steps of: (a) combining an aqueous slurry of metallic nickel or cobalt and, optionally, at least one metal selected from manganese and aluminum with an oxidant selected from nitrate and peroxide in a reaction vessel under an atmosphere with less than 100 ppm O 2, thereby obtaining an aqueous reaction medium with a pH value in the range of from 7.5 to 12 containing particles, (b) removing the particles from step (a) from the liquid by a solid-liquid separation method, and drying the particles, (c) returning mother liquor obtained in step (b) to the reaction vessel. (a) combining an aqueous slurry of metallic nickel or cobalt and, optionally, at least one metal selected from manganese and aluminum with an oxidant selected from nitrate and peroxide in a reaction vessel under an atmosphere with less than 100 ppm O 2, thereby obtaining an aqueous reaction medium with a pH value in the range of from 7.5 to 12 containing particles, (b) removing the particles from step (a) from the liquid by a solid-liquid separation method, and drying the particles, (c) returning mother liquor obtained in step (b) to the reaction vessel.
A display medium comprising a display layer for authenticity identification, wherein the display layer contains a droplet-cured product and the droplet-cured product contains a resin having cholesteric regularity, characterized in that the display layer further contains a metal particle and a half width of a selective reflection band within the visible wavelength region of the droplet-cured product is greater than 100 nm. the display layer contains a droplet-cured product and the droplet-cured product contains a resin having cholesteric regularity, characterized in that the display layer further contains a metal particle and a half width of a selective reflection band within the visible wavelength region of the droplet-cured product is greater than 100 nm.
Front flap module for a vehicle, wherein the front flap module consists of a coupling shaft, a coupling device accommodated in the coupling shaft, and at least one front flap which can be moved using front flap cinematics and which can at least partially cover the coupling shaft, characterized by a covering device which can be arranged on the coupling shaft and which has a cladding which, on the one hand, is releasably fastened to the coupling shaft in a region of an opening of the coupling shaft and, on the other hand, to the coupling device.
Implant formed as an intraluminal endoprosthesis comprising a basic structure formed as a hollow cylinder, wherein a nonwoven fabric arranged in and/or on the basic structure, wherein the basic structure comprises a magnesium alloy or a polymer selected from the class of biodegradable polymers, wherein at least one section of the implant further comprises a fastening means (2", 12, 14, 16, 18, 20) or the nonwoven fabric treated to prevent or reduce, at least in an expanded state of the implant, either a protrusion of nonwoven fabric sections from the basic structure, and/or formation of more extensive regions, which comprises fibers or fiber sections protruding from the basic structure, characterized in that the fastening means is formed by a hydrogel and/or a hydrogel-based adhesive, which is arranged at the outer side of the nonwoven fabric.
A method of making a titanium alloy, the method comprising: providing a homogenous mixture comprising solid titanium raw feed material, the solid raw feed material being used in preparing a metal melt, where "metal melt" refers to a melt of a metal and, optionally, metal and non-metal alloying additives that is subsequently solidified into an alloy, and a quantity of formed articles, the formed articles comprising a predetermined quantity of a master alloy consisting of titanium dioxide particles, wherein the formed articles comprise particles of the master alloy bound together by at least one organic polymer binder that decomposes at a predetermined temperature that is greater than 260°C (500°F) and releases the particles of master alloy and wherein the formed articles comprise 5% to 60% by weight of the at least one organic polymer binder; and heating the mixture at a temperature above the predetermined temperature to melt the solid raw feed material and release the particles of the master alloy in the formed articles and prepare a melt; wherein the solid raw feed material and the formed articles are mixed prior to melting of the solid raw feed material; and subsequently solidifying the mixture of melted raw feed materials and master alloy to form an alloy having a desired chemistry. providing a homogenous mixture comprising solid titanium raw feed material, the solid raw feed material being used in preparing a metal melt, where "metal melt" refers to a melt of a metal and, optionally, metal and non-metal alloying additives that is subsequently solidified into an alloy, and a quantity of formed articles, the formed articles comprising a predetermined quantity of a master alloy consisting of titanium dioxide particles, wherein the formed articles comprise particles of the master alloy bound together by at least one organic polymer binder that decomposes at a predetermined temperature that is greater than 260°C (500°F) and releases the particles of master alloy and wherein the formed articles comprise 5% to 60% by weight of the at least one organic polymer binder; and heating the mixture at a temperature above the predetermined temperature to melt the solid raw feed material and release the particles of the master alloy in the formed articles and prepare a melt; wherein the solid raw feed material and the formed articles are mixed prior to melting of the solid raw feed material; and subsequently solidifying the mixture of melted raw feed materials and master alloy to form an alloy having a desired chemistry.
An adhesive wafer for an ostomy device, the wafer comprising a proximal adhesive layer, a backing layer on the distal side of the adhesive layer, and a hole for accommodating a stoma, a connection zone for attaching a collecting bag, circumferending the hole in a radial distance, characterized in that the wafer comprises a release layer configured to releasing a neutralizer on the distal side of the backing layer, the release layer is located on at least a central portion of the backing layer, the central portion being defined as the area extending radially from the edge of the hole to the connection zone, wherein the neutralizer is selected from the group consisting of: Amberlite IRA 958 chloride, Deurex Pure, Diaion WA30, Cholestyramine, Dianion HP 20, Dianion HP 2MG, Toyo Pearl, Kaolin (from adhesive lab), Calcium acetate, Calcium carbonate, Zinc sulfate, Zinc oxide, Strontium chloride, Lima bean inhibitor, Ovomucoids, pancreatic inhibitor/ Kunitz inhibitor, Aprotinin, papaya Kunitz-type trypsin inhibitor, soybean trypsin inhibitor, potato trypsin inhibitor, barley trypsin inhibitor and squash trypsin inhibitor.
A compound of formula I: wherein X is N or CH; R 1 is H, CD 3, C 1-3 alkyl or C 3-6 cycloalkyl; R 2 is C 1-6 alkoxy; R 3 is C 1-3 alkyl, C 1-3 alkoxy, -NHS p R a or -S p R a;R 4 is absent or a 5-7 membered heterocycle substituted with 0-3 R 5; R 5 is H, halogen, C 1-3 alkyl, C 1-3 alkyl C 1-3 alkoxy, --(CH 2) r 5-8 membered heterocycle substituted with 0-2 R 5a or -CO-3-8 membered heterocycle; R 5a is SO 2 - C 1-6 alkyl or COO- C 1-6 alkyl; R a is C 1-3 alkyl or C 3-6 cycloalkyl; p is 1 or 2; r is 0, 1, 2, 3, 4 or 5; or a stereoisomer or pharmaceutically acceptable salt thereof. X is N or CH; R 1 is H, CD 3, C 1-3 alkyl or C 3-6 cycloalkyl; R 2 is C 1-6 alkoxy; R 3 is C 1-3 alkyl, C 1-3 alkoxy, -NHS p R a or -S p R a;R 4 is absent or a 5-7 membered heterocycle substituted with 0-3 R 5; R 5 is H, halogen, C 1-3 alkyl, C 1-3 alkyl C 1-3 alkoxy, --(CH 2) r 5-8 membered heterocycle substituted with 0-2 R 5a or -CO-3-8 membered heterocycle; R 5a is SO 2 - C 1-6 alkyl or COO- C 1-6 alkyl; R a is C 1-3 alkyl or C 3-6 cycloalkyl; p is 1 or 2; r is 0, 1, 2, 3, 4 or 5; or a stereoisomer or pharmaceutically acceptable salt thereof.
A low beam optical module, comprising a lens, a light-shielding sheet and at least one light concentrating portion, wherein, the light concentrating portion and the light-shielding sheet are formed as an integrated part, the light-shielding sheet comprises a light-shielding sheet body; an upper edge of a front end of the light-shielding sheet body is provided with a low beam cutoff line structure; a front end surface and a rear end surface of the light-shielding sheet body are transparent; the light concentrating portion is connected to a rear end of the light-shielding sheet; the lens is arranged in front of the light-shielding sheet; and an outer contour surface of the at least one light concentrating portion is engaged with a lower surface of the light-shielding sheet body, so that when in use, a part of the light emitted by the light concentrating portion can pass above the light-shielding sheet body and then enter into the lens to form a low beam shape located below the low beam cutoff line (a), and the light-shielding sheet body can receive a part of the emitted light of the light concentrating portion and refract the light from the front end surface to the lens, and then the light is projected to form a low beam region III beam shape. comprising a lens, a light-shielding sheet and at least one light concentrating portion, wherein, the light concentrating portion and the light-shielding sheet are formed as an integrated part, the light-shielding sheet comprises a light-shielding sheet body; an upper edge of a front end of the light-shielding sheet body is provided with a low beam cutoff line structure; a front end surface and a rear end surface of the light-shielding sheet body are transparent; the light concentrating portion is connected to a rear end of the light-shielding sheet; the lens is arranged in front of the light-shielding sheet; and an outer contour surface of the at least one light concentrating portion is engaged with a lower surface of the light-shielding sheet body, so that when in use, a part of the light emitted by the light concentrating portion can pass above the light-shielding sheet body and then enter into the lens to form a low beam shape located below the low beam cutoff line (a), and the light-shielding sheet body can receive a part of the emitted light of the light concentrating portion and refract the light from the front end surface to the lens, and then the light is projected to form a low beam region III beam shape.
An electronic circuit (30; 45; 50) comprising a semiconductor or conductive substrate having first and second opposite surfaces (8, 10) and at least first and second electric insulation trenches (12, 14), not parallel, comprising walls, extending in the substrate from the first surface, delimiting at least a portion of the substrate and joining at a junction, the portion of the substrate comprising a protrusion penetrating into the junction, wherein the first trench comprises, on the side of said portion, a first planar wall and wherein the second trench comprises, on the side of said portion, a second planar wall, the first planar wall being coupled to the second planar wall by a connection surface successively comprising, from the first planar wall to the second planar wall, a first curved surface delimiting a portion of convex volume of the first trench, a second curved surface delimiting a portion of concave volume of the junction, and a third curved surface delimiting a portion of convex volume of the second trench, and wherein the first, second, and third surfaces (36, 38, 40) correspond, in a plane parallel to the first surface, respectively to first, second, and third arcs of a circle.
A handheld tool adapted to facilitate the removal of an aerofoil from an array of aerofoils for a gas turbine engine, the tool comprising: a body portion, and first and second jaw members (24,26) depending from the body portion, wherein the first jaw member is shaped to be insertable between a first aerofoil and an adjacent aerofoil in the array so as to contact a first portion of the first aerofoil, the first portion of the first aerofoil being on a suction side of the aerofoil part way between a leading edge of the aerofoil and a trailing edge of the aerofoil, and the second jaw member is adapted to contact a further portion of the first aerofoil, the further portion of the first aerofoil being on an opposing pressure side of the aerofoil at one of the leading edge and the trailing edge of the aerofoil, the position of the first and/or second jaw member (24,26) being adjustable to selectively grip the first aerofoil therebetween in use, characterized in that the body portion comprises an upstanding impact formation adapted to receive impact forces applied by a user in a direction towards the aerofoil held between the first and second jaw members, and transfer the impact forces to the first and/or second jaw member (24,26) in use. a body portion, and first and second jaw members (24,26) depending from the body portion, wherein the first jaw member is shaped to be insertable between a first aerofoil and an adjacent aerofoil in the array so as to contact a first portion of the first aerofoil, the first portion of the first aerofoil being on a suction side of the aerofoil part way between a leading edge of the aerofoil and a trailing edge of the aerofoil, and the second jaw member is adapted to contact a further portion of the first aerofoil, the further portion of the first aerofoil being on an opposing pressure side of the aerofoil at one of the leading edge and the trailing edge of the aerofoil, the position of the first and/or second jaw member (24,26) being adjustable to selectively grip the first aerofoil therebetween in use, characterized in that the body portion comprises an upstanding impact formation adapted to receive impact forces applied by a user in a direction towards the aerofoil held between the first and second jaw members, and transfer the impact forces to the first and/or second jaw member (24,26) in use.