A multiaxial machine tool for working stone slabs and/or blocks, comprising: - a primary beam extending along a substantially horizontal first axis (X 1), and having associated therewith first guide means, substantially parallel to said first axis (X 1); - means for anchoring said primary beam to the ground; - a carriage slidably mounted to said first guide means; - a secondary beam extending along a substantially horizontal third axis (X 3), and having associated therewith third guide means, substantially parallel to said third axis (X 3); - connection means for rotatably connecting said secondary beam to said carriage about a substantially vertical fourth axis (X 4); - one or more tool-carrying heads slidably mounted to said secondary beam along said third guide means; - a support table for supporting the products being processed; - characterized in that said ground anchoring means have associated therewith second guide means parallel to a substantially horizontal second axis (X 2) perpendicular to the first axis (X 1), for slidably guiding said primary beam, said secondary beam having a pair of side faces, at least one of which has associated therewith said third guide means, said secondary beam being suitable for removable mounting of said one or more tool-carrying heads and for their removal and replacement with one or more tool-carrying heads having tools for working and handling respectively which may be equal and different respectively, said tools being selected from the group comprising cutting blades, abrasive grinders, water jets, suction cup manipulator or similar vacuum-operated means, each of said one or more tool-carrying heads having associated therewith a support with a first portion having sliding means adapted for removable coupling with said third guide means and a second portion for supporting said at least one tool (16, 16') for working and handling respectively. - a primary beam extending along a substantially horizontal first axis (X 1), and having associated therewith first guide means, substantially parallel to said first axis (X 1); - means for anchoring said primary beam to the ground; - a carriage slidably mounted to said first guide means; - a secondary beam extending along a substantially horizontal third axis (X 3), and having associated therewith third guide means, substantially parallel to said third axis (X 3); - connection means for rotatably connecting said secondary beam to said carriage about a substantially vertical fourth axis (X 4); - one or more tool-carrying heads slidably mounted to said secondary beam along said third guide means; - a support table for supporting the products being processed; - characterized in that said ground anchoring means have associated therewith second guide means parallel to a substantially horizontal second axis (X 2) perpendicular to the first axis (X 1), for slidably guiding said primary beam, said secondary beam having a pair of side faces, at least one of which has associated therewith said third guide means, said secondary beam being suitable for removable mounting of said one or more tool-carrying heads and for their removal and replacement with one or more tool-carrying heads having tools for working and handling respectively which may be equal and different respectively, said tools being selected from the group comprising cutting blades, abrasive grinders, water jets, suction cup manipulator or similar vacuum-operated means, each of said one or more tool-carrying heads having associated therewith a support with a first portion having sliding means adapted for removable coupling with said third guide means and a second portion for supporting said at least one tool (16, 16') for working and handling respectively.