An anti-folder hand safety door, comprising: a door frame comprising a header, a threshold, a first door jamb and a second door jamb, said first door jamb and said second door jamb being bilaterally connected between said header and said threshold to face toward each other, said first door jamb comprising a recess located on one side thereof and facing toward said second door jamb; a door panel comprising a top side pivotally connected to said header of said door frame, an opposing bottom side, a mounting hole defined in the bottom side thereof and a convex hanging stile located on one lateral side thereof and facing toward said first door jamb of said door frame, said convex hanging stile being received in said recess of said first door jamb of said door frame when said door panel is closed in said door frame; characterized in that it comprises an adjustment mechanism comprising a holder frame, a movable plate, a locating shaft and a fixed gear, said holder frame being mounted to a top surface of said threshold of said door frame adjacent to said first door jamb of said door frame, said movable plate being mounted in said holder frame and movable toward said first door jamb of said door frame, said locating shaft having a bottom side thereof affixed to said movable plate, said fixed gear being fixedly mounted on said locating shaft; and a door closer comprising a body, a rotating shaft and a transmission gear, said body being mounted in said mounting hole of said door panel and pivotally connected to an opposing top side of said locating shaft so that said body is turnable about said locating shaft when said door panel is opened from said door frame, said rotating shaft being rotatably mounted in said body with a top end thereof disposed inside said body and an opposing bottom end thereof extended outside said body, said transmission gear being affixed to the bottom end of said rotating shaft and meshed with said fixed gear of said adjustment mechanism for driving said rotating shaft to rotate relative to said body. a door frame comprising a header, a threshold, a first door jamb and a second door jamb, said first door jamb and said second door jamb being bilaterally connected between said header and said threshold to face toward each other, said first door jamb comprising a recess located on one side thereof and facing toward said second door jamb; a door panel comprising a top side pivotally connected to said header of said door frame, an opposing bottom side, a mounting hole defined in the bottom side thereof and a convex hanging stile located on one lateral side thereof and facing toward said first door jamb of said door frame, said convex hanging stile being received in said recess of said first door jamb of said door frame when said door panel is closed in said door frame; characterized in that it comprises an adjustment mechanism comprising a holder frame, a movable plate, a locating shaft and a fixed gear, said holder frame being mounted to a top surface of said threshold of said door frame adjacent to said first door jamb of said door frame, said movable plate being mounted in said holder frame and movable toward said first door jamb of said door frame, said locating shaft having a bottom side thereof affixed to said movable plate, said fixed gear being fixedly mounted on said locating shaft; and a door closer comprising a body, a rotating shaft and a transmission gear, said body being mounted in said mounting hole of said door panel and pivotally connected to an opposing top side of said locating shaft so that said body is turnable about said locating shaft when said door panel is opened from said door frame, said rotating shaft being rotatably mounted in said body with a top end thereof disposed inside said body and an opposing bottom end thereof extended outside said body, said transmission gear being affixed to the bottom end of said rotating shaft and meshed with said fixed gear of said adjustment mechanism for driving said rotating shaft to rotate relative to said body.