mhurhangee/ep-ind-claims huggingface dataset:
The compound N-(4-((3-(2-amino-4-pyrimidinyl)-2-pyridinyl)oxy)phenyl)-4-(4-methyl-2-thienyl)-1-phthalazinamine or a pharmaceutically acceptable salt thereof for use in the treatment of cancer in a subject, wherein the cancer is selected from the group consisting of breast cancer, lung cancer, colon cancer, uterine cancer, liver cancer, kidney cancer and multiple myeloma or a combination thereof, and the cancer is refractory to prior treatment with a chemotherapeutic agent, an anti-neoplastic agent, AZD1152, PHA-739538, MK-0457 or a combination thereof.
A sheath (20, 220, 230), comprising: a sheath body (24, 224, 324) having a front plate and a back plate spaced apart from the front plate, the front plate and back plate defining a cavity therein, the cavity being externally accessible through an opening formed between the front plate and the back plate; and a plurality of snapping fasteners positioned about the back plate of the sheath body (24, 224, 324), the plurality of snapping fasteners each including a male component and a female component mounted on opposite sides of the back plate, the male component including a protrusion extending away from the sheath body (24, 224, 324), and the female component defining a recess complimentary to the protrusion. a sheath body (24, 224, 324) having a front plate and a back plate spaced apart from the front plate, the front plate and back plate defining a cavity therein, the cavity being externally accessible through an opening formed between the front plate and the back plate; and a plurality of snapping fasteners positioned about the back plate of the sheath body (24, 224, 324), the plurality of snapping fasteners each including a male component and a female component mounted on opposite sides of the back plate, the male component including a protrusion extending away from the sheath body (24, 224, 324), and the female component defining a recess complimentary to the protrusion.
An apparatus for producing a multicoloured design on a surface of a beverage or a food item, the apparatus comprising: a stencil mount (30; 110) comprising at least one first locating member (36; 118); and at least two stencils (10, 20; 50, 60; 120); each stencil defining a horizontal plane and comprising at least one second locating member (16; 26; 122), wherein each stencil is adapted to rest upon the stencil mount in such a way that the at least one first locating member (36; 118) engages with the at least one second locating member (16; 26; 122), thereby inhibiting or preventing rotation of the stencil within the horizontal plane and inhibiting or preventing lateral movement of the stencil relative to the stencil mount; and wherein the stencils (10, 20; 50, 60; 120) have complementary apertures of (14, 24; 54, 68) different shapes and dimensions which, due to the predetermined positional relationship of the stencils to the stencil mount, combine and complement one another to produce multicoloured patterns, designs or images on the beverage or food item when each stencil has a granulated substance of a different colour dispersed through its apertures, characterised in that the stencil mount and the stencil are substantially flat. a stencil mount (30; 110) comprising at least one first locating member (36; 118); and at least two stencils (10, 20; 50, 60; 120); each stencil defining a horizontal plane and comprising at least one second locating member (16; 26; 122), wherein each stencil is adapted to rest upon the stencil mount in such a way that the at least one first locating member (36; 118) engages with the at least one second locating member (16; 26; 122), thereby inhibiting or preventing rotation of the stencil within the horizontal plane and inhibiting or preventing lateral movement of the stencil relative to the stencil mount; and wherein the stencils (10, 20; 50, 60; 120) have complementary apertures of (14, 24; 54, 68) different shapes and dimensions which, due to the predetermined positional relationship of the stencils to the stencil mount, combine and complement one another to produce multicoloured patterns, designs or images on the beverage or food item when each stencil has a granulated substance of a different colour dispersed through its apertures, characterised in that the stencil mount and the stencil are substantially flat.
A high-strength steel wire comprising, by wt%, carbon: 0.52% to 0.72%, manganese (Mn): 0.6% to 0.8%, silicon (Si): 0.1% to 0.4%, nickel (Ni): 0.3% to 1.2%, vanadium: 0.3% to 1.2%, and a balance of iron (Fe) and inevitable impurities, wherein after a drawing process, the high-strength steel wire has a carbon content of 20 at. % or less in cementite within pearlite, wherein the high-strength steel wire has a pearlite lamellar spacing of 180 nm or less, and wherein the high-strength steel wire has a tensile strength of 1450 MPa or greater and an elongation of 13% or greater. wherein after a drawing process, the high-strength steel wire has a carbon content of 20 at. % or less in cementite within pearlite, wherein the high-strength steel wire has a pearlite lamellar spacing of 180 nm or less, and wherein the high-strength steel wire has a tensile strength of 1450 MPa or greater and an elongation of 13% or greater.
Computer-implemented method for representing operator control information in the context of a technical installation, which has at least one operator station server and one operator station client, the method comprising: a) Receiving measurement values of at least one technical object (8,9) of the technical installation by means of the operator station server; b) Continuously generating an actual trend progression of the measurement value, wherein, in the event that no measurement value can be received from the at least one technical object (8, 9), an interpolation of the measurement value is undertaken to generate an interpolated trend progression, until a measurement value can be received once again; c) Transferring the actual and the interpolated trend progression from the operator station server to the operator station client; d) Visually presenting the actual and the interpolated trend progression to an operator of the technical installation in a common trend progression diagram; wherein the method is characterised by the following steps: e) In the event that the actual measurement values of at least one technical object (8, 9), which have occurred during a period of time of the presentation of the interpolated trend progression, can be received from the operator station server retrospectively, then using the relevant actual measurement values from the operator station server to generate the actual trend progression of the measurement value and transferring a comparison of the interpolated and the actual trend progression to the operator station client for visual presentation to the operator of the technical installation. a) Receiving measurement values of at least one technical object (8,9) of the technical installation by means of the operator station server; b) Continuously generating an actual trend progression of the measurement value, wherein, in the event that no measurement value can be received from the at least one technical object (8, 9), an interpolation of the measurement value is undertaken to generate an interpolated trend progression, until a measurement value can be received once again; c) Transferring the actual and the interpolated trend progression from the operator station server to the operator station client; d) Visually presenting the actual and the interpolated trend progression to an operator of the technical installation in a common trend progression diagram; wherein the method is characterised by the following steps: e) In the event that the actual measurement values of at least one technical object (8, 9), which have occurred during a period of time of the presentation of the interpolated trend progression, can be received from the operator station server retrospectively, then using the relevant actual measurement values from the operator station server to generate the actual trend progression of the measurement value and transferring a comparison of the interpolated and the actual trend progression to the operator station client for visual presentation to the operator of the technical installation.
A tape cartridge attachably/detachably installed on a cartridge installation portion of a tape printing apparatus having the cartridge installation portion and a press switch, the cartridge installation portion having an installation base portion and an installation peripheral wall portion surrounding the installation base portion and allowing the tape cartridge to be installed thereon, the press switch having a stem projecting in a direction crossing an installation direction and provided on the installation peripheral wall portion, the tape cartridge comprising: a detected portion that is provided on an outer peripheral surface of the tape cartridge and corresponds to the stem when the tape cartridge is installed on the cartridge installation portion, wherein the detected portion has an installation guide slant surface that presses the stem when the tape cartridge is installed on the cartridge installation portion characterized in that the cartridge installation portion allows n types (where n is an integer of two or more) of the tape cartridges having a different thickness in the installation direction to be installed thereon, the press switch includes n press switches, each of which is different in distance from the installation base portion to a direction opposite to the installation direction, on the installation peripheral wall portion, the detected portion includes n detected portions on the outer peripheral surface of the tape cartridge, and one or more and (n - 1) or less of the n detected portions and the detected portions different in number according to the thickness of the tape cartridge further have a removing guide slant surface that releases pressing of the stem when the tape cartridge is installed on the cartridge installation portion and presses the stem when the tape cartridge is removed from the cartridge installation portion. a detected portion that is provided on an outer peripheral surface of the tape cartridge and corresponds to the stem when the tape cartridge is installed on the cartridge installation portion, wherein the detected portion has an installation guide slant surface that presses the stem when the tape cartridge is installed on the cartridge installation portion characterized in that the cartridge installation portion allows n types (where n is an integer of two or more) of the tape cartridges having a different thickness in the installation direction to be installed thereon, the press switch includes n press switches, each of which is different in distance from the installation base portion to a direction opposite to the installation direction, on the installation peripheral wall portion, the detected portion includes n detected portions on the outer peripheral surface of the tape cartridge, and one or more and (n - 1) or less of the n detected portions and the detected portions different in number according to the thickness of the tape cartridge further have a removing guide slant surface that releases pressing of the stem when the tape cartridge is installed on the cartridge installation portion and presses the stem when the tape cartridge is removed from the cartridge installation portion.
A housing assembly, comprising a housing, a decorating part, and an adhesive assembly, wherein the housing is provided with a through hole; the decorating part comprises a substrate and a decorating ring protruding from the substrate; an air hole is disposed on the substrate; the air hole is located on an outer side of the decorating ring; the decorating ring is at least partially accommodated in the through hole; a gap is formed between an outer peripheral side surface of the decorating ring and a hole wall of the through hole; the adhesive assembly is attached between the substrate and the housing in a sealed manner; the adhesive assembly is disposed around the decorating ring and the air hole, and a channel is formed between the adhesive assembly and the outer peripheral side surface of the decorating ring; and the channel communicates with the gap and the air hole; characterized in that the channel continuously surrounds an outer periphery of the decorating ring; and the decorating ring has a groove; the groove is disposed in a circumferential direction of the decorating ring; the groove is recessed from the outer peripheral side surface of the decorating ring towards an interior of the decorating ring; and the groove communicates with the gap and the channel. the channel continuously surrounds an outer periphery of the decorating ring; and the decorating ring has a groove; the groove is disposed in a circumferential direction of the decorating ring; the groove is recessed from the outer peripheral side surface of the decorating ring towards an interior of the decorating ring; and the groove communicates with the gap and the channel.
Apparatus for converting energy from waves in a body of water, the apparatus comprising: - a main body, adapted to float onto the water; - a first anchor line connected to the main body at two horizontally distinct locations, and adapted to be anchored to the bottom of the body of water at two points, which two points are located at a distance from one another in a first direction; and - a second anchor line connected to the main body at two horizontally distinct locations, and adapted to be anchored to the bottom of the body of water at two further points, which two further points are located at a distance from one another in a second direction that is substantially perpendicular to the said first direction; and - rotation means connected to the main body and to the first and second anchor line, such that a horizontal first movement of the main body with respect to the two points and/or the two further points results in a second movement of the rotation means, - conversion means adapted to convert the second movement in another form of energy, and - coiling means for controlling the vertical position of the main body by adapting the length of the first and second anchor line, characterized in that the coiling means are formed as a differential wherein the first anchor line is coiled at a first side gear and the second anchor line is coiled at a second side gear of the differential, and wherein a crown gear of the differential is operated to adapt the vertical position. - a main body, adapted to float onto the water; - a first anchor line connected to the main body at two horizontally distinct locations, and adapted to be anchored to the bottom of the body of water at two points, which two points are located at a distance from one another in a first direction; and - a second anchor line connected to the main body at two horizontally distinct locations, and adapted to be anchored to the bottom of the body of water at two further points, which two further points are located at a distance from one another in a second direction that is substantially perpendicular to the said first direction; and - rotation means connected to the main body and to the first and second anchor line, such that a horizontal first movement of the main body with respect to the two points and/or the two further points results in a second movement of the rotation means, - conversion means adapted to convert the second movement in another form of energy, and - coiling means for controlling the vertical position of the main body by adapting the length of the first and second anchor line,
A Continuity Check, CC, protocol optimization method in a switch (302A, 600), the method comprising: operating a plurality of CC sessions with a peer switch (302D, 600), wherein, for CC intervals, N sessions of the plurality of CC sessions are set to a short interval and M sessions of the plurality of CC sessions are set to a long interval, wherein N and M are integers; switching a first session of the N sessions with a second session of the M sessions based on one of a fault and user provisioning; and characterized by automatically exchanging the CC intervals between the first session and the second session subsequent to the switching, wherein the automatic exchange is through one of Type-Length-Value, TLV, fields and renegotiation in Bidirectional Forwarding Detection, BFD. operating a plurality of CC sessions with a peer switch (302D, 600), wherein, for CC intervals, N sessions of the plurality of CC sessions are set to a short interval and M sessions of the plurality of CC sessions are set to a long interval, wherein N and M are integers; switching a first session of the N sessions with a second session of the M sessions based on one of a fault and user provisioning; and characterized by automatically exchanging the CC intervals between the first session and the second session subsequent to the switching, wherein the automatic exchange is through one of Type-Length-Value, TLV, fields and renegotiation in Bidirectional Forwarding Detection, BFD.
Device (20, 42) for determining a torque acting on a drive shaft, comprising: - a field generating device which is firmly connected to the drive shaft or a coupling of the same and which, in the surroundings of the drive shaft, generates a magnetic field that depends on the torque, characterized by - an organic magnetoresistive OMR semiconductor element, which is arranged in a stationary manner in the surroundings, wherein the OMR semiconductor element forms an OLED, and - a voltage source for generating an electric voltage between two electrodes (24, 26) of the OMR semiconductor element. - a field generating device which is firmly connected to the drive shaft or a coupling of the same and which, in the surroundings of the drive shaft, generates a magnetic field that depends on the torque, characterized by - an organic magnetoresistive OMR semiconductor element, which is arranged in a stationary manner in the surroundings, wherein the OMR semiconductor element forms an OLED, and - a voltage source for generating an electric voltage between two electrodes (24, 26) of the OMR semiconductor element.
A computing device comprising: an in-memory database; an external database compute unit configured to generate a schema in the in-memory database based on a portion of an external database, wherein the in-memory database is configured to use a first defined database query language and the external database is configured to use a second defined database query language that differs from the first defined database query language; a relational search unit configured to receive a request for data and generate a resolved-request including an ordered sequence of tokens that represent the request for data; a semantic interface configured to interface with the in-memory database and interface with the external database, wherein the semantic interface is further configured to receive the resolved-request and to generate a data-query based on the in-memory database schema for execution on the external database on a condition that a previous data-query associated with the data-query was executed on the external database; an external database specific serializer configured to generate an external database specific query based on the data-query in accordance with the second defined database query language; and an interface unit configured to receive results data responsive to the execution of the external database specific query from the external database via the semantic interface and output the results data for display on a user interface. an in-memory database; an external database compute unit configured to generate a schema in the in-memory database based on a portion of an external database, wherein the in-memory database is configured to use a first defined database query language and the external database is configured to use a second defined database query language that differs from the first defined database query language; a relational search unit configured to receive a request for data and generate a resolved-request including an ordered sequence of tokens that represent the request for data; a semantic interface configured to interface with the in-memory database and interface with the external database, wherein the semantic interface is further configured to receive the resolved-request and to generate a data-query based on the in-memory database schema for execution on the external database on a condition that a previous data-query associated with the data-query was executed on the external database; an external database specific serializer configured to generate an external database specific query based on the data-query in accordance with the second defined database query language; and an interface unit configured to receive results data responsive to the execution of the external database specific query from the external database via the semantic interface and output the results data for display on a user interface.
A measuring device for determining the displacement of a rotating object provided with a light reflective surface with an accuracy of nanometers and nanoradials, which object prior to or during the displacement may tilt over a relatively large angle, which measuring device comprises an optical system, as well as a light source which sends a light beam into the optical system, and a sensor which measures and outputs parameters of the light beam leaving the optical system, which optical system comprises a beam splitter provided with a light splitting surface having a front side directed towards the light source and a rear side facing away of the light source, of which beam splitter the light splitting surface is at 45° with respect to the light beam emitted by the light source, as well as a reflector of which the light reflecting surface is parallel to the light beam transmitted by the light source and is located on the front side of the light splitting surface and is under 45° with respect to light splitting surface of the beam splitter, and a corner cube which is present opposite the reflector at the other side of the beam splitter, wherein the light reflecting surface of the rotating object to be measured is located at the rear of the light splitting surface of the beam splitter and in line with the light beam emitted by the light source, which optical system is such that it forwards at least a part of the incoming light beam to the light reflecting surface of the object and forwards the light beam reflected from the object to the sensor, which measuring device further comprises a further optical system which comprises one or more of the following elements: further reflectors (23; 37; 57), retro-reflectors (15, 19; 31, 35; 51) and lenses (15; 31), characterized in that the further optical system is between the optical system and the light reflecting surface of the rotating object to be measured, said further optical system is such that it returns an incoming sub light beam reflected from the light reflecting surface of the object to be measured in opposite direction and at the same place as it entered into the further optical system.
A double-stranded nucleic acid (dsNA) comprising first and second nucleic acid strands forming a duplex structure wherein said first strand is 15-35 nucleotides in length and said second strand is 19-35 nucleotides in length and wherein said dsNA is complementary to the target HAO1 mRNA sequence as set forth in SEQ. ID. NO: 1823 along at least 19 consecutive nucleotides of said second strand and reduces HAO1 target mRNA expression when introduced into a mammalian cell which expresses said mRNA in vivo.