A medical device, comprising: a surgical cutting assembly insertable within an instrument channel of an endoscope having a torque generation component or a torque delivery component disposed within a portion of the endoscope insertable within a mammalian cavity of a patient, the surgical cutting assembly configured to resect material at a surgical site within the mammalian cavity of the patient and including an outer cannula including a cutting window; an inner cannula disposed within the outer cannula; a flexible outer tubing coupled to a proximal end of the outer cannula, the outer cannula and the outer tubing having a first length that exceeds a length of the instrument channel of the endoscope within which the surgical cutting assembly is insertable; a coupling member having a distal end coupled to the proximal end of the inner cannula; and an aspiration tubing disposed within an inner wall of the flexible outer tubing and fluidly coupled to the inner cannula via the coupling member, wherein the inner cannula, the coupling member and the aspiration tubing having a second length that exceeds the length of the instrument channel of the endoscope (5000,) within which the surgical cutting assembly is insertable, and wherein the inner cannula, the coupling member and the aspiration tubing defining an aspiration channel through which the material resected by the surgical cutting assembly is removed from the surgical site within the mammalian cavity of the patient to outside the mammalian cavity; characterised by: a coupling assembly including a stationary portion and a movable portion, the movable portion coupled to the coupling member and the stationary portion coupled to the aspiration tubing, the coupling assembly configured to cause the coupling member to move relative to the aspiration tubing responsive to actuation of a corresponding coupling component that is integral to a distal end of the endoscope, the corresponding coupling component of the endoscope positioned adjacent to or surrounding the instrument channel of the endoscope. an outer cannula including a cutting window; an inner cannula disposed within the outer cannula; a flexible outer tubing coupled to a proximal end of the outer cannula, the outer cannula and the outer tubing having a first length that exceeds a length of the instrument channel of the endoscope within which the surgical cutting assembly is insertable; a coupling member having a distal end coupled to the proximal end of the inner cannula; and an aspiration tubing disposed within an inner wall of the flexible outer tubing and fluidly coupled to the inner cannula via the coupling member, wherein the inner cannula, the coupling member and the aspiration tubing having a second length that exceeds the length of the instrument channel of the endoscope (5000,) within which the surgical cutting assembly is insertable, and wherein the inner cannula, the coupling member and the aspiration tubing defining an aspiration channel through which the material resected by the surgical cutting assembly is removed from the surgical site within the mammalian cavity of the patient to outside the mammalian cavity; characterised by: a coupling assembly including a stationary portion and a movable portion, the movable portion coupled to the coupling member and the stationary portion coupled to the aspiration tubing, the coupling assembly configured to cause the coupling member to move relative to the aspiration tubing responsive to actuation of a corresponding coupling component that is integral to a distal end of the endoscope, the corresponding coupling component of the endoscope positioned adjacent to or surrounding the instrument channel of the endoscope.