mhurhangee/ep-ind-claims huggingface dataset:
A composition for use in a method of treating a medical condition, the method comprising the step of administering to a patient a thermoreversible, thermoplastic, pharmaceutical composition comprising a biologically active botulinum toxin and a thermoreversible, thermoplastic poloxamer by intramuscular or subcutaneous injection or by insertion of a depot or implant, wherein the pharmaceutical composition is administered as a liquid having a first viscosity in a temperature range between 0 and 10 °C and becomes a gel having a second viscosity between 30 and 40°C after the administration, whereby the second viscosity is higher than the first viscosity, and; therapeutic amounts of the botulinum toxin are released from the composition in vivo for at least 1 week after the administration.
A method for intelligent data compression in a portable computing device, PCD, the method comprising: determining a fixation point within an image frame by a fixation point sensor, wherein the fixation point sensor is configured to determine an area of user focus within a given image frame; sectoring the image frame into two or more sectors, wherein the two or more sectors comprise a fixation sector that includes the fixation point and one or more foveated sectors (L2-L6), each foveated sector does not include the fixation point, and each sector comprises a plurality of tiles; compressing the image frame such that the fixation sector is compressed according to a compression algorithm having a low compression factor and the one or more foveated sectors are compressed according to a compression algorithm having a high compression factor, wherein each respective tile within a particular foveated sector is subject to a different compression factor that is based on a distance between the fixation sector and the respective tile, each compression factor of a respective tile within a foveated sector having a magnitude that is assigned corresponding to the distance between the fixation sector and a respective tile; and storing the compressed image frame. determining a fixation point within an image frame by a fixation point sensor, wherein the fixation point sensor is configured to determine an area of user focus within a given image frame; sectoring the image frame into two or more sectors, wherein the two or more sectors comprise a fixation sector that includes the fixation point and one or more foveated sectors (L2-L6), each foveated sector does not include the fixation point, and each sector comprises a plurality of tiles; compressing the image frame such that the fixation sector is compressed according to a compression algorithm having a low compression factor and the one or more foveated sectors are compressed according to a compression algorithm having a high compression factor, wherein each respective tile within a particular foveated sector is subject to a different compression factor that is based on a distance between the fixation sector and the respective tile, each compression factor of a respective tile within a foveated sector having a magnitude that is assigned corresponding to the distance between the fixation sector and a respective tile; and storing the compressed image frame.
An electronic module comprising: a bracket, wherein the bracket comprises a housing; and a first electronic component and a second electronic component, characterized in that the bracket further comprises a barrier rib, a conductive paste is coated on the barrier rib, the first electronic component and the second component are accommodated in the housing, in contact with the conductive paste, and spaced from each other by the barrier rib, and electrically connected to each other through the conductive paste. a bracket, wherein the bracket comprises a housing; and a first electronic component and a second electronic component, characterized in that the bracket further comprises a barrier rib, a conductive paste is coated on the barrier rib, the first electronic component and the second component are accommodated in the housing, in contact with the conductive paste, and spaced from each other by the barrier rib, and electrically connected to each other through the conductive paste.
A method of making a porous sintered body, comprising: a pellet making step of making a compound pellet by heating and mixing a sintering compound containing a binder, a sinterable powder material and a pore formation material at a temperature causing the binder to melt but not causing the pore formation material to soften, whereby the sintering compound contains the pore formation material at a rate of 50 through 80 volume percent of the sintering compound; a thermal formation step of forming the pellet made in the pellet making step into a predetermined shape at a temperature causing the binder to melt but not causing the pore formation material to deform; a degreasing step of removing the binder from a formed body obtained from the thermal formation step; and a sintering step of sintering a degreased body after the degreasing step, wherein the binder contains a component which melts at a temperature attained in the pellet making step and the formation step and drains at a temperature higher than a temperature at which the pore formation material drains, the pore formation material being drained in the degreasing step, with part of the binder remaining un-drained, wherein the binder component is drained by a 0.1 volume percent through 5.0 volume percent before the pore formation material begins draining, wherein the binder component remains un-drained by 5 volume percent through 40 volume percent upon complete drainage of the pore formation material, and wherein the porous sintered body has a porosity of 50 to 80 %. a pellet making step of making a compound pellet by heating and mixing a sintering compound containing a binder, a sinterable powder material and a pore formation material at a temperature causing the binder to melt but not causing the pore formation material to soften, whereby the sintering compound contains the pore formation material at a rate of 50 through 80 volume percent of the sintering compound; a thermal formation step of forming the pellet made in the pellet making step into a predetermined shape at a temperature causing the binder to melt but not causing the pore formation material to deform; a degreasing step of removing the binder from a formed body obtained from the thermal formation step; and a sintering step of sintering a degreased body after the degreasing step, wherein the binder contains a component which melts at a temperature attained in the pellet making step and the formation step and drains at a temperature higher than a temperature at which the pore formation material drains, the pore formation material being drained in the degreasing step, with part of the binder remaining un-drained, wherein the binder component is drained by a 0.1 volume percent through 5.0 volume percent before the pore formation material begins draining, wherein the binder component remains un-drained by 5 volume percent through 40 volume percent upon complete drainage of the pore formation material, and wherein the porous sintered body has a porosity of 50 to 80 %.
A meniscus implant for replacing damaged meniscal tissue, comprising: a porous body having a plurality of interconnected open micro-pores and more than one open cavities for receiving meniscal tissue, wherein the interconnected micro-pores are arranged to allow fluid to flow into the porous body and are in fluid communication with the more than one open cavities. a porous body having a plurality of interconnected open micro-pores and more than one open cavities for receiving meniscal tissue, wherein the interconnected micro-pores are arranged to allow fluid to flow into the porous body and are in fluid communication with the more than one open cavities.
Method for routing synchronization messages in a packet communication network, in which a packet is routed by means of a routing table, referred to as a global routing table, said method comprising the following steps implemented by a piece of equipment in the network: - detection of a packet carrying a synchronization message in a packet stream; - determination of at least one output port; - sending of a packet carrying the modified synchronization message to the determined output port, the synchronization message being modified using a piece of information that is representative of a transit time for said equipment; characterized in that the method furthermore comprises: - a step of configuration of a synchronization routing table that stores at least one association between an input port and at least one output port; - a step of verification that the packet carrying the received synchronization message indicates that routing by means of the synchronization routing table needs to be carried out, the output port for said packet carrying the synchronization message then being determined on the basis of an input port on which the packet carrying the synchronization message is received and by reading the synchronization routing table. - detection of a packet carrying a synchronization message in a packet stream; - determination of at least one output port; - sending of a packet carrying the modified synchronization message to the determined output port, the synchronization message being modified using a piece of information that is representative of a transit time for said equipment; - a step of configuration of a synchronization routing table that stores at least one association between an input port and at least one output port; - a step of verification that the packet carrying the received synchronization message indicates that routing by means of the synchronization routing table needs to be carried out,
Assembly for medical use for injecting a patient with a liquid or viscous product, such as a contrast product, characterized in that the assembly comprises: - an injection line for the transfer of the product to be injected between a container and the patient, said injection line comprising an upstream tubular part, a downstream tubular part and a thresholded non-return valve on the downstream tubular part, said thresholded non-return value allowing the liquid product to pass from the container to the patient, - a filling line for the transfer of the product to be injected between a feed source and the container via the upstream tubular part, said filling line being connected to the injection line between the upstream and downstream tubular parts (11, 12) and comprising a non-return valve allowing the liquid product to pass from the feed source to the container, - a coupling interface on the filling line intended to be coupled to a pumping unit allowing for the displacement of the liquid between the feed source and the container. - an injection line for the transfer of the product to be injected between a container and the patient, said injection line comprising an upstream tubular part, a downstream tubular part and a thresholded non-return valve on the downstream tubular part, said thresholded non-return value allowing the liquid product to pass from the container to the patient, - a filling line for the transfer of the product to be injected between a feed source and the container via the upstream tubular part, said filling line being connected to the injection line between the upstream and downstream tubular parts (11, 12) and comprising a non-return valve allowing the liquid product to pass from the feed source to the container, - a coupling interface on the filling line intended to be coupled to a pumping unit allowing for the displacement of the liquid between the feed source and the container.
An endoluminal biopsy tool, said tool comprising an outer tube, and an instrument provided in the outer tube, wherein the outer tube and the instrument are movable with respect to each other for taking the biopsy, wherein the instrument is an inner tube movably fitting inside the outer tube, wherein the inner tube has a wall that is provided with a cut out, characterized in that the outer tube is provided with a tongue extending from a distal portion of the outer tube, and further characterised in that the cut out in the wall of the inner tube is closable with the tongue. wherein the instrument is an inner tube movably fitting inside the outer tube, wherein the inner tube has a wall that is provided with a cut out, characterized in that the outer tube is provided with a tongue extending from a distal portion of the outer tube, and further characterised in that the cut out in the wall of the inner tube is closable with the tongue.
A computer-implemented method for providing a real-time estimate of glycosylated hemoglobin (HbA1c) of a patient having Type 1 diabetes from a self-monitoring blood glucose (SMBG) measurement, and tracking changes in average glycemia of said patient over time, the method comprising the steps of: computing a surrogate fasting measurement, based on unstructured SMBG data received from the patient on consecutive days, wherein said unstructured SMBG data is aggregated according to time bins for said consecutive days; computing a glycation value using the said surrogate fasting measurement and a calibration offset in a predetermined glycation equation, wherein said calibration offset is calculated according to components of a blood glucose profile computed from values of said aggregated unstructured SMBG data, such that said BG profile defines a surrogate for a seven-point SMBG profile for said patient; outputting said glycation value as an initial estimate of HbA1c upon initialization of tracking of said patient's average glycemia; updating said glycation value by using an updated SMBG value in said predetermined glycation equation, said updated SMBG value being based on a subsequent computed surrogate fasting measurement; computing an updated estimate of HbA1c using said initial estimate of HbA1c and said updated glycation value in a predetermined HbA1c estimation equation; and outputting said updated estimate of HbA1c to a user. computing a surrogate fasting measurement, based on unstructured SMBG data received from the patient on consecutive days, wherein said unstructured SMBG data is aggregated according to time bins for said consecutive days; computing a glycation value using the said surrogate fasting measurement and a calibration offset in a predetermined glycation equation, wherein said calibration offset is calculated according to components of a blood glucose profile computed from values of said aggregated unstructured SMBG data, such that said BG profile defines a surrogate for a seven-point SMBG profile for said patient; outputting said glycation value as an initial estimate of HbA1c upon initialization of tracking of said patient's average glycemia; updating said glycation value by using an updated SMBG value in said predetermined glycation equation, said updated SMBG value being based on a subsequent computed surrogate fasting measurement; computing an updated estimate of HbA1c using said initial estimate of HbA1c and said updated glycation value in a predetermined HbA1c estimation equation; and outputting said updated estimate of HbA1c to a user.
Fluid washing composition with four separate components housed in respective independent tanks of a laundry washing machine equipped with a programme for the selection, dosing and differentiated delivery of said separated components according to the varying characteristics of the individual laundry batch, characterised in that said separate components have the following formulation: Component 1 - detergent formulation with a pH ranging between 4.0 and 12.0, with high detergent effect in washing programmes at temperatures in the range 40°-60°C, having a specific action on cotton fibres and, in particular, on white-coloured items; Component 2 - detergent formulation with a pH ranging between 8.0 and 12.0, with high detergent effect in washing programmes at temperatures in the range 15°-40°C, having a specific action on synthetic, coloured and animal-origin fibres; Component 3 - enzyme-based stain-removing formulation based at least on subtilisin-type protease and lipase and possibly amylase with a pH ranging between 5.0 and 6.0 and preferably between 5.0 and 5.5, stabilised with sorbitol, calcium chloride and overall content of monopropylene glycol not above 10% of active agent; Component 4 - after-wash conditioning formulation, with a pH ranging between 2.0 and 4.0, whereby distributing said components across four different and independent volumes, separating the components enzymes and surfactants. Component 1 - detergent formulation with a pH ranging between 4.0 and 12.0, with high detergent effect in washing programmes at temperatures in the range 40°-60°C, having a specific action on cotton fibres and, in particular, on white-coloured items; Component 2 - detergent formulation with a pH ranging between 8.0 and 12.0, with high detergent effect in washing programmes at temperatures in the range 15°-40°C, having a specific action on synthetic, coloured and animal-origin fibres; Component 3 - enzyme-based stain-removing formulation based at least on subtilisin-type protease and lipase and possibly amylase with a pH ranging between 5.0 and 6.0 and preferably between 5.0 and 5.5, stabilised with sorbitol, calcium chloride and overall content of monopropylene glycol not above 10% of active agent; Component 4 - after-wash conditioning formulation, with a pH ranging between 2.0 and 4.0, whereby distributing said components across four different and independent volumes, separating the components enzymes and surfactants.
A method for detecting an analyte in a sample, comprising: (a) contacting said sample with at least one set of at least first and second proximity probes, which probes each comprise an analyte-binding domain and a nucleic acid domain and can simultaneously bind to the analyte; (b) allowing the nucleic acid domains of the proximity probes to interact with each other upon binding of said proximity probes to said analyte, wherein said interaction comprises the formation of a duplex; (c) extending the 3' end of at least one nucleic acid domain of said duplex to generate an extension product, wherein the extension reaction comprises increasing the temperature of the assay above room temperature and uses a polymerase enzyme which is characterised as having less than 20% of its maximal enzyme activity at 40°C and having less than 10% of its maximal enzyme activity at 25°C, wherein the optimum temperature for maximal activity of the polymerase is more than 40°C and wherein the polymerase is selected from Pyrococcus furiosus (Pfu) DNA polymerase and Pyrococcus woesei (Pwo) DNA polymerase or a derivative or mutant thereof, preferably wherein said derivative is a sequence-modified derivative; and (d) amplifying and detecting the extension product. (a) contacting said sample with at least one set of at least first and second proximity probes, which probes each comprise an analyte-binding domain and a nucleic acid domain and can simultaneously bind to the analyte; (b) allowing the nucleic acid domains of the proximity probes to interact with each other upon binding of said proximity probes to said analyte, wherein said interaction comprises the formation of a duplex; (c) extending the 3' end of at least one nucleic acid domain of said duplex to generate an extension product, wherein the extension reaction comprises increasing the temperature of the assay above room temperature and uses a polymerase enzyme which is characterised as having less than 20% of its maximal enzyme activity at 40°C and having less than 10% of its maximal enzyme activity at 25°C, wherein the optimum temperature for maximal activity of the polymerase is more than 40°C and wherein the polymerase is selected from Pyrococcus furiosus (Pfu) DNA polymerase and Pyrococcus woesei (Pwo) DNA polymerase or a derivative or mutant thereof, preferably wherein said derivative is a sequence-modified derivative; and (d) amplifying and detecting the extension product.
An electronic device comprising: a plurality of electronic components (410, 420) mounted into the electronic device; a processor operatively connected to the electronic components (410, 420); and a memory storing instructions that, when executed by the processor, cause the electronic device to: classify a plurality of areas of the electronic device into a plurality of prediction areas (430, 530), wherein the plurality of prediction areas (430, 530) is classified based on predetermined characteristics of whether an area of the electronic device includes an electronic component (410, 420) and whether a current of the electronic component (410, 420) is measured; configure a virtual thermistor corresponding to each of the plurality of prediction areas (430, 530), based on the classification of the plurality of prediction areas (430, 530), wherein the virtual thermistor is configured as a virtualized sensor for predicting temperature; collect information on each of the plurality of prediction areas (430, 530), based on the virtual thermistor; and manage temperature for each of the plurality of prediction areas (430, 530), based on the collected information. a plurality of electronic components (410, 420) mounted into the electronic device; a processor operatively connected to the electronic components (410, 420); and a memory storing instructions that, when executed by the processor, cause the electronic device to: classify a plurality of areas of the electronic device into a plurality of prediction areas (430, 530), wherein the plurality of prediction areas (430, 530) is classified based on predetermined characteristics of whether an area of the electronic device includes an electronic component (410, 420) and whether a current of the electronic component (410, 420) is measured; configure a virtual thermistor corresponding to each of the plurality of prediction areas (430, 530), based on the classification of the plurality of prediction areas (430, 530), wherein the virtual thermistor is configured as a virtualized sensor for predicting temperature; collect information on each of the plurality of prediction areas (430, 530), based on the virtual thermistor; and manage temperature for each of the plurality of prediction areas (430, 530), based on the collected information. classify a plurality of areas of the electronic device into a plurality of prediction areas (430, 530), wherein the plurality of prediction areas (430, 530) is classified based on predetermined characteristics of whether an area of the electronic device includes an electronic component (410, 420) and whether a current of the electronic component (410, 420) is measured; configure a virtual thermistor corresponding to each of the plurality of prediction areas (430, 530), based on the classification of the plurality of prediction areas (430, 530), wherein the virtual thermistor is configured as a virtualized sensor for predicting temperature; collect information on each of the plurality of prediction areas (430, 530), based on the virtual thermistor; and manage temperature for each of the plurality of prediction areas (430, 530), based on the collected information.
A coating composition comprising: a hydrophobic first aliphatic polyisocyanate; a second aliphatic polyisocyanate comprising a hydrophilic portion; a polyester polyol being a polycaprolactone polyol, a polycaprolactone diol, or a mixture thereof having a weight average molecular weight in a range of 300 to 5,000 g/mole; a hydrophilic polyol; a fluorinated polyol, and a fluorinated alcohol comprising a perfluorinated carbon chain and a hydroxyl group. a hydrophobic first aliphatic polyisocyanate; a second aliphatic polyisocyanate comprising a hydrophilic portion; a polyester polyol being a polycaprolactone polyol, a polycaprolactone diol, or a mixture thereof having a weight average molecular weight in a range of 300 to 5,000 g/mole; a hydrophilic polyol; a fluorinated polyol, and a fluorinated alcohol comprising a perfluorinated carbon chain and a hydroxyl group.