mhurhangee/ep-ind-claims huggingface dataset:
A high intensity focused ultrasound, HIFU, system for real-time, image-guided HIFU treatment of tissue of a patient, the system comprising: a HIFU applicator configured to deliver HIFU energy to the tissue; a HIFU generator configured to control and transmit the HIFU energy to the HIFU applicator; an ultrasound imaging device configured to control imaging of the tissue so as to provide, during operation of the HIFU system, 1) a real-time view of a first image plane that is parallel to a line passing through a feature of the HIFU applicator, and 2) a real-time view of a second image plane that is orthogonal to the first image plane, wherein the feature of the HIFU applicator visually provides to a user of the HIFU system a corresponding indication that correlates an orientation of a displayed image plane to the patient; and a user interface including a display, wherein the user interface is configured to display images of the tissue on the display which provide three-dimensional visualization of the tissue, wherein the display simultaneously includes an active parallel frame depicting the real-time view of the first image plane parallel to the feature of the HIFU applicator and an active orthogonal frame depicting the real-time view of the second image plane orthogonal to the first image plane depicted in the active parallel frame. a HIFU applicator configured to deliver HIFU energy to the tissue; a HIFU generator configured to control and transmit the HIFU energy to the HIFU applicator; an ultrasound imaging device configured to control imaging of the tissue so as to provide, during operation of the HIFU system, 1) a real-time view of a first image plane that is parallel to a line passing through a feature of the HIFU applicator, and 2) a real-time view of a second image plane that is orthogonal to the first image plane, wherein the feature of the HIFU applicator visually provides to a user of the HIFU system a corresponding indication that correlates an orientation of a displayed image plane to the patient; and a user interface including a display, wherein the user interface is configured to display images of the tissue on the display which provide three-dimensional visualization of the tissue, wherein the display simultaneously includes an active parallel frame depicting the real-time view of the first image plane parallel to the feature of the HIFU applicator and an active orthogonal frame depicting the real-time view of the second image plane orthogonal to the first image plane depicted in the active parallel frame.
Clutch device which is mounted such that it can be rotated about a rotational axis, having: - an input side, an output side, at least one friction package with at least one first friction partner and at least one second friction partner, and a boosting device, - the first friction partner being connected in a torque-transmitting manner to the input side, - the second friction partner being connected in a torque-transmitting manner to the output side, - it being possible for the first and the second friction partner (55, 60) to be brought into frictional engagement by way of a pressing force, in order to transmit a torque between the input side and the output side, - the output side having an output shaft and an output element, - the output element being coupled to the output shaft at least in an axial direction, - a hub being provided which is connected in a torque-transmitting manner to the output shaft and can be displaced axially with respect to the output shaft, and - the boosting device being configured to load the pressing force with a boosting force (F A), - characterized in that a limiting device is arranged between the hub and a supporting device, - the limiting device being configured to limit the pressing force and/or the boosting force (F A) at least partially, and comprising at least one spring means, - the spring means being configured as a compression spring or as a cup spring or as a tension spring or as a leaf spring, and being prestressed with a prestressing force which has a value which corresponds to a sum of the pressing force and a predefined value of the boosting force (F A). - an input side, an output side, at least one friction package with at least one first friction partner and at least one second friction partner, and a boosting device, - the first friction partner being connected in a torque-transmitting manner to the input side, - the second friction partner being connected in a torque-transmitting manner to the output side, - it being possible for the first and the second friction partner (55, 60) to be brought into frictional engagement by way of a pressing force, in order to transmit a torque between the input side and the output side, - the output side having an output shaft and an output element, - the output element being coupled to the output shaft at least in an axial direction, - a hub being provided which is connected in a torque-transmitting manner to the output shaft and can be displaced axially with respect to the output shaft, and - the boosting device being configured to load the pressing force with a boosting force (F A), - characterized in that a limiting device is arranged between the hub and a supporting device, - the limiting device being configured to limit the pressing force and/or the boosting force (F A) at least partially, and comprising at least one spring means, - the spring means being configured as a compression spring or as a cup spring or as a tension spring or as a leaf spring, and being prestressed with a prestressing force which has a value which corresponds to a sum of the pressing force and a predefined value of the boosting force (F A).
A method of enriching one or more target nucleic acids in a sample, comprising: (a) annealing one or more probes to the one or more target nucleic acid molecules in the sample to form one or more probe-target nucleic acid molecule complexes, wherein the one or more probes each comprise a constant region and a unique region, wherein the unique region of each probe includes a nucleotide sequence which hybridizes to a complementary nucleic acid sequence within the one or more target nucleic acid molecules; (b) extending the one or more probe-target nucleic acid molecule complexes to form one or more extended probe-target nucleic acid molecule complexes, and performing A-tailing; (c) generating one or more ligation products from the one or more extended probe-target nucleic acid molecule complexes; (d) introducing one or more primers to the generated one or more ligation products, wherein the one or more primers hybridize to one or more complementary portions of the constant region within each of the one or more ligation products; and (e) amplifying the one or more ligation products in the presence of a polymerase to provide one or more amplification products, wherein the one or more probes each include a bridge oligonucleotide comprising a 3' overhang and having Formula: 3' - - 5', wherein comprises between 5 and 50 nucleotides, and where at least a portion of the nucleotide sequence of is complementary to the constant region, and the 3' overhang is a T overhang. (a) annealing one or more probes to the one or more target nucleic acid molecules in the sample to form one or more probe-target nucleic acid molecule complexes, wherein the one or more probes each comprise a constant region and a unique region, wherein the unique region of each probe includes a nucleotide sequence which hybridizes to a complementary nucleic acid sequence within the one or more target nucleic acid molecules; (b) extending the one or more probe-target nucleic acid molecule complexes to form one or more extended probe-target nucleic acid molecule complexes, and performing A-tailing; (c) generating one or more ligation products from the one or more extended probe-target nucleic acid molecule complexes; (d) introducing one or more primers to the generated one or more ligation products, wherein the one or more primers hybridize to one or more complementary portions of the constant region within each of the one or more ligation products; and (e) amplifying the one or more ligation products in the presence of a polymerase to provide one or more amplification products,
A portable transporter for holding a portable housing and for providing hypothermic perfusion, wherein the transporter is configured to operate at any temperatures in the range of -25°C to 60 °C, comprising: a base portion configured to facilitate an upright position of the transporter; a top portion; a pump configured to control the flow of perfusate within the transporter to deliver the perfusate to an organ; a power supply; a compartment for holding the portable housing that is configured to contain the organ; a perfusion reservoir; a watertight additional compartment for holding a coolant, configured such that heat from the walls of the perfusion reservoir and the portable housing may be conducted into the coolant; and means for controlling the temperature of at least one of the perfusate and the organ with the coolant and a thermal controller, wherein the portable transporter further comprises a heater configured to raise the temperature of the perfusate. a base portion configured to facilitate an upright position of the transporter; a top portion; a pump configured to control the flow of perfusate within the transporter to deliver the perfusate to an organ; a power supply; a compartment for holding the portable housing that is configured to contain the organ;
A cosmetic method for ameliorating hyperpigmentation of human skin comprising topically applying to an area of the skin in need thereof an effective amount of an active agent selected from the group of botanical extracts of Amorphophallus campanulatus, Gomphrena globose Linn., Fibraretinum resica Pierre (Fibrauretine), Vernonia cinerea Linn. Less, Cayratia japonica, Pteris semipinnata and 5-chloro-salicylic acid, 3,6-Nonadienol, cis-6-nonenol and the compounds: and combinations thereof.
Rotor blade for a wind turbine, comprising a longitudinal rotor blade base body having a longitudinal axis, whereby a stiffening structure is disposed within the base body, whereby the stiffening structure is divided in at least two, axially adjacently disposed stiffening structure segments (6a, 6b), whereby at least one first stiffening structure segment is disposed with a different orientation relative to the longitudinal axis of the base body compared with at least one further stiffening structure segment, wherein axially adjacently disposed stiffening structure segments (6a, 6b) at least partially overlap each other in axial direction, characterised in that each stiffening structure segment (6a, 6b) is a composite component that comprises a stiffening web structure built of a fibre based fabric within a matrix material.
A laundry drying machine of the type comprising a heat pump system (20; 120; 220; 320) having a refrigerant circuit (30; 130; 230; 330) for a refrigerant and comprising an air stream circuit for an air stream conveyable to a laundry drum suited to receive laundry to be dried, said refrigerant circuit (30; 130; 230; 330) comprising: - a first heat exchanger for a thermal coupling between said air stream circuit and said refrigerant circuit (30; 130; 230; 330) wherein the refrigerant is cooled down and said air stream is heated up; - a second heat exchanger for a further thermal coupling between said air stream circuit and said refrigerant circuit (30; 130; 230; 330) wherein the refrigerant is heated up and said air stream is cooled down; - a compressor arranged in said refrigerant circuit (30; 130; 230; 330) between said second heat exchanger and said first heat exchanger; - a refrigerant expansion device (22; 122) arranged in said refrigerant circuit (30; 130; 230; 330) between said first heat exchanger and said second heat exchanger; and two or more interrupting devices (71, 72; 171, 172; 122) arranged along said refrigerant circuit (30; 130; 230; 330) suited to define one or more portions of said refrigerant circuit (30; 130; 230; 330) where said refrigerant may be confined; cha racterized by a leakage sensor, wherein said interrupting devices (71, 72; 171, 172; 122) are closed when a refrigerant leakage is detected by said leakage sensor. - a first heat exchanger for a thermal coupling between said air stream circuit and said refrigerant circuit (30; 130; 230; 330) wherein the refrigerant is cooled down and said air stream is heated up; - a second heat exchanger for a further thermal coupling between said air stream circuit and said refrigerant circuit (30; 130; 230; 330) wherein the refrigerant is heated up and said air stream is cooled down; - a compressor arranged in said refrigerant circuit (30; 130; 230; 330) between said second heat exchanger and said first heat exchanger; - a refrigerant expansion device (22; 122) arranged in said refrigerant circuit (30; 130; 230; 330) between said first heat exchanger and said second heat exchanger; and
Method for detecting an activated brake of a vehicle, comprising the following method steps: a. detecting the vehicle speed v, b. detecting the total torque M total generated by at least one drive of the vehicle for propulsion, characterized by the following, further method steps: c. determining the braking force F B, which acts on the vehicle, depending on the vehicle speed v and the total torque M total when the vehicle speed v is greater than a minimum speed v min, d. generating a signal, which represents an activated brake, when the braking force F B is greater than a first threshold value S1. a. detecting the vehicle speed v, b. detecting the total torque M total generated by at least one drive of the vehicle for propulsion, c. determining the braking force F B, which acts on the vehicle, depending on the vehicle speed v and the total torque M total when the vehicle speed v is greater than a minimum speed v min, d. generating a signal, which represents an activated brake, when the braking force F B is greater than a first threshold value S1.
A pulp lifter for installation in a grinding mill downstream of a grate/screen (12; 150) formed with apertures/holes (13; 152) that allow slurry to pass to the pulp lifter for removal from the mill by the pulp lifter, the pulp lifter having a leading edge and a trailing edge with respect to rotation of the mill and comprising: a first wall means bounding an interior space, and a second wall means dividing the interior space into first (15; 115) and second (16; 116) sections, wherein the first wall means includes a leading edge wall formed with an inlet opening (17; 117) providing access to the second section (16; 116) and an inner edge wall (25; 106) formed with an outlet opening for discharge of slurry from the second section, the second wall means includes a guide (18; 112) that extends substantially from an outer end of the leading edge wall to a trailing end of an inner edge wall, and the first section (15; 115) of said interior space is open at the trailing edge of the pulp lifter. a first wall means bounding an interior space, and a second wall means dividing the interior space into first (15; 115) and second (16; 116) sections, wherein the first wall means includes a leading edge wall formed with an inlet opening (17; 117) providing access to the second section (16; 116) and an inner edge wall (25; 106) formed with an outlet opening for discharge of slurry from the second section, the second wall means includes a guide (18; 112) that extends substantially from an outer end of the leading edge wall to a trailing end of an inner edge wall, and the first section (15; 115) of said interior space is open at the trailing edge of the pulp lifter.
An enhanced mattress configured for enabling passive involuntary digestive tract movement, shoulder opening and pelvis bones movement, the mattress being configured solely for prone lying of a human body thereupon and comprising: a head support section configured to support a head of the human body, the head support section comprising an open face section; an upper main section connected to the head support section, the upper main section configured to support shoulders and an abdomen of the human body, the upper main section comprising a plurality of dedicated supporting members, each being smaller than the upper main section and having a greater firmness therefrom; a lower support section connected to the upper main section, the lower support section configured to support a pelvis of the human body. a head support section configured to support a head of the human body, the head support section comprising an open face section; an upper main section connected to the head support section, the upper main section configured to support shoulders and an abdomen of the human body, the upper main section comprising a plurality of dedicated supporting members, each being smaller than the upper main section and having a greater firmness therefrom; a lower support section connected to the upper main section, the lower support section configured to support a pelvis of the human body.
An auxiliary switch comprising: a housing including a first housing part and a second housing part separate from and releasably connected to the first housing part; a printed circuit board fixedly mounted within the housing and having an electrical pad; a terminal conductor electrically connected to the printed circuit board; and an actuator mechanism mounted within the housing and having an electrical contactor engaged to the terminal conductor, characterised in that the printed circuit board has an electrical contact connected to the electrical pad and the actuator mechanism is configured to move within the housing and at least partially displace the electrical contact while maintaining engagement between the contactor and the terminal conductor. a housing including a first housing part and a second housing part separate from and releasably connected to the first housing part; a printed circuit board fixedly mounted within the housing and having an electrical pad; a terminal conductor electrically connected to the printed circuit board; and an actuator mechanism mounted within the housing and having an electrical contactor engaged to the terminal conductor, characterised in that the printed circuit board has an electrical contact connected to the electrical pad and the actuator mechanism is configured to move within the housing and at least partially displace the electrical contact while maintaining engagement between the contactor and the terminal conductor.
A stent device delivery system, comprising: a stent device, and an outer sheath overlaying the stent device in a radially compact, delivery configuration of the stent device; the outer sheath is retractable to allow the stent device to radially expand to a deployed configuration; a pull member for pulling proximally on to retract the outer sheath; wherein a portion of the outer sheath is heat shrunk radially onto a relatively heat shrink resistant support member in order to capture a distal portion of the pull member radially between the outer sheath and the heat shrink resistant support member, characterized in that the outer sheath comprises an inner layer, an outer layer and a fold-over portion connecting the inner layer and the outer layer, the fold-over portion is axially movable relative to the stent device by moving the inner layer relative to the outer layer, thereby allowing the outer sheath to be retracted from the stent device and the outer layer is heat shrunk onto the heat shrink resistant support member to capture the pull member. a stent device, and an outer sheath overlaying the stent device in a radially compact, delivery configuration of the stent device; the outer sheath is retractable to allow the stent device to radially expand to a deployed configuration; a pull member for pulling proximally on to retract the outer sheath; wherein a portion of the outer sheath is heat shrunk radially onto a relatively heat shrink resistant support member in order to capture a distal portion of the pull member radially between the outer sheath and the heat shrink resistant support member, characterized in that the outer sheath comprises an inner layer, an outer layer and a fold-over portion connecting the inner layer and the outer layer, the fold-over portion is axially movable relative to the stent device by moving the inner layer relative to the outer layer, thereby allowing the outer sheath to be retracted from the stent device and the outer layer is heat shrunk onto the heat shrink resistant support member to capture the pull member.
A method for the removal of inorganic components from raw material for the production of clean materials, wherein the raw material is biomass, coal, residues from urban or industrial origin, wastes from urban or industrial origin, or sludges from sewage treatment plants, or any combination thereof, the method including: preparing an aqueous solution that contains one or more organic and/or inorganic salt(s) of calcium, magnesium, aluminum, titanium and/or ammonium, wherein the concentration of the salt(s) in the aqueous solution varies from 0.1% to 30% w/w in water volume; and washing of the raw material with the aqueous solution, wherein the washing is realized at a raw material to aqueous solution ratio from 33 g/l up to 600 g/l, at a temperature that varies from 13 °C up to 95 °C, and at a washing time that varies from 5 minutes to 24 hours. preparing an aqueous solution that contains one or more organic and/or inorganic salt(s) of calcium, magnesium, aluminum, titanium and/or ammonium, wherein the concentration of the salt(s) in the aqueous solution varies from 0.1% to 30% w/w in water volume; and washing of the raw material with the aqueous solution, wherein the washing is realized at a raw material to aqueous solution ratio from 33 g/l up to 600 g/l, at a temperature that varies from 13 °C up to 95 °C, and at a washing time that varies from 5 minutes to 24 hours.