A stimulation system for detecting and identifying a stimulation threshold to avoid tetany of a patient's muscles, wherein the system comprises: an input device for obtaining electrical potential data from the patient's physiological system after application of stimulation to the patient's tissue; at least one processor; and at least one memory storing instructions which, when executed by the at least one data processor, result in operations comprising: stimulating (402, 404; 508) tissue with a sequence of pulses delivered at a current level and a frequency, the stimulating including increasing the current level of each pulse in the sequence of pulses from an immediately preceding pulse; determining (406; 510) that a first evocation pulse from the sequence of pulses evokes a first muscular response; continuing to stimulate (408; 518, 522) the tissue with a second evocation pulse from the sequence of pulses to evoke a second muscular response, the stimulating comprising: decreasing the frequency of the delivery of each pulse in the sequence of pulses; and increasing the current level of each pulse in the sequence of pulses from the immediately preceding pulse by a second current increment; and determining (410; 532) that the second evocation pulse from the sequence of pulses evokes the second muscular response. an input device for obtaining electrical potential data from the patient's physiological system after application of stimulation to the patient's tissue; at least one processor; and at least one memory storing instructions which, when executed by the at least one data processor, result in operations comprising: stimulating (402, 404; 508) tissue with a sequence of pulses delivered at a current level and a frequency, the stimulating including increasing the current level of each pulse in the sequence of pulses from an immediately preceding pulse; determining (406; 510) that a first evocation pulse from the sequence of pulses evokes a first muscular response; continuing to stimulate (408; 518, 522) the tissue with a second evocation pulse from the sequence of pulses to evoke a second muscular response, the stimulating comprising: decreasing the frequency of the delivery of each pulse in the sequence of pulses; and increasing the current level of each pulse in the sequence of pulses from the immediately preceding pulse by a second current increment; and determining (410; 532) that the second evocation pulse from the sequence of pulses evokes the second muscular response. stimulating (402, 404; 508) tissue with a sequence of pulses delivered at a current level and a frequency, the stimulating including increasing the current level of each pulse in the sequence of pulses from an immediately preceding pulse; determining (406; 510) that a first evocation pulse from the sequence of pulses evokes a first muscular response; continuing to stimulate (408; 518, 522) the tissue with a second evocation pulse from the sequence of pulses to evoke a second muscular response, the stimulating comprising: decreasing the frequency of the delivery of each pulse in the sequence of pulses; and increasing the current level of each pulse in the sequence of pulses from the immediately preceding pulse by a second current increment; and decreasing the frequency of the delivery of each pulse in the sequence of pulses; and increasing the current level of each pulse in the sequence of pulses from the immediately preceding pulse by a second current increment; and determining (410; 532) that the second evocation pulse from the sequence of pulses evokes the second muscular response.