mhurhangee/ep-ind-claims huggingface dataset:
A pharmaceutical composition for use in treating a subject having a neurodegenerative disease comprising a compound having the structure wherein bond α is present or absent; R 1 and R 2 is each independently H, O - or OR 9, where R 9 is H, alkyl, alkenyl, alkynyl or aryl, or R 1 and R 2 together are =O; R 3 and R 4 are each different, and each is OH, O -, OR 9, SH, S, SR 9, or where X is O, S, NR 10, or N + R 10 R 10, where each R 10 is independently H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, -CH 2 CN, -CH 2 CO 2 R 11, -CH 2 COR 11, -NHR 11 or -NH + (R 11) 2, where each R 11 is independently alkyl, alkenyl or alkynyl, each of which is substituted or unsubstituted, or H; R 5 and R 6 is each independently H, OH, or R 5 and R 6 taken together are =O; and R 7 and R 8 is each independently H, F, Cl, Br, SO 2 Ph, CO 2 CH 3, or SR 12, where R 12 is H, aryl or a substituted or unsubstituted alkyl, alkenyl or alkynyl, wherein the substituted alkyl, substituted alkenyl, and substituted alkynyl are substituted with one or more substituents selected from halo, hydroxy, mercapto, amino, carboxy, cyano and carbamoyl, and the substituted aryl is substituted with a substituent selected from amine, alkylamine, hydroxyl and alkylhydroxy, or a salt, enantiomer or zwitterion of the compound. bond α is present or absent; R 1 and R 2 is each independently H, O - or OR 9, where R 9 is H, alkyl, alkenyl, alkynyl or aryl, or R 1 and R 2 together are =O; where R 9 is H, alkyl, alkenyl, alkynyl or aryl, or R 1 and R 2 together are =O; R 3 and R 4 are each different, and each is OH, O -, OR 9, SH, S, SR 9, where X is O, S, NR 10, or N + R 10 R 10, where each R 10 is independently H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, -CH 2 CN, -CH 2 CO 2 R 11, -CH 2 COR 11, -NHR 11 or -NH + (R 11) 2, where each R 11 is independently alkyl, alkenyl or alkynyl, each of which is substituted or unsubstituted, or H; R 5 and R 6 is each independently H, OH, or R 5 and R 6 taken together are =O; and R 7 and R 8 is each independently H, F, Cl, Br, SO 2 Ph, CO 2 CH 3, or SR 12, where R 12 is H, aryl or a substituted or unsubstituted alkyl, alkenyl or alkynyl, where each R 10 is independently H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, -CH 2 CN, -CH 2 CO 2 R 11, -CH 2 COR 11, -NHR 11 or -NH + (R 11) 2, where each R 11 is independently alkyl, alkenyl or alkynyl, each of which is substituted or unsubstituted, or H; R 5 and R 6 is each independently H, OH, or R 5 and R 6 taken together are =O; and R 7 and R 8 is each independently H, F, Cl, Br, SO 2 Ph, CO 2 CH 3, or SR 12, where R 12 is H, aryl or a substituted or unsubstituted alkyl, alkenyl or alkynyl, where R 12 is H, aryl or a substituted or unsubstituted alkyl, alkenyl or alkynyl,
An isolated polypeptide consisting of an amino acid sequence selected from the group consisting of: (i) RRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAK (SEQ ID NO:7), (ii) SEQ ID NO:7 further including 1-5 conservative amino acid substitutions, wherein the peptide inhibits cell-cell interaction, inhibits Aβ production or binds to a β-APP, (iii) DEEEDEEL (SEQ ID NO:5), (iv) RRSLGHPEPLSNGRP (SEQ ID NO:6), (v) SEQ ID NO:6 further including 1-5 conservative amino acid substitutions, wherein the peptide inhibits cell-cell interaction, inhibits Aβ production or binds to a β-APP, (vi) any of the foregoing comprising an unnatural amino acid or D-amino acid, wherein the peptide inhibits cell-cell interaction, inhibits Aβ production or binds to a β-APP. (i) RRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAK (SEQ ID NO:7), (ii) SEQ ID NO:7 further including 1-5 conservative amino acid substitutions, wherein the peptide inhibits cell-cell interaction, inhibits Aβ production or binds to a β-APP, (iii) DEEEDEEL (SEQ ID NO:5), (iv) RRSLGHPEPLSNGRP (SEQ ID NO:6), (v) SEQ ID NO:6 further including 1-5 conservative amino acid substitutions, wherein the peptide inhibits cell-cell interaction, inhibits Aβ production or binds to a β-APP, (vi) any of the foregoing comprising an unnatural amino acid or D-amino acid, wherein the peptide inhibits cell-cell interaction, inhibits Aβ production or binds to a β-APP.
A surface layer on a substrate comprising structurally integrated minerals grown from a zwitterionic polymer template, wherein the zwitterionic polymers are covalently linked to the substrate surface, wherein the substrate is a metallic or ceramic substrate; and the substrate is characterized by having a porous surface.
A multi-column sequenced separation process on resin for separating an ionic metal derivative from a leaching solution containing an ionic metal derivative, by passing said solution on a fixed resin bed and comprising at least three zones, liquid flow means being arranged between adjacent zones and between the last and the first zone, said process comprising several sequences, each sequence comprising at least one step chosen from an adsorption step, a rinsing step, a desorption step, implemented simultaneously or not, each following sequence is done by the displacement of the fronts in the zones in the downstream direction by substantially a same increment before the periodic displacement of the introduction and withdrawal points.
An active magnetic rotor-bearing assembly for conveying a fluid F) comprising a rotor assembly driven by a motor assembly to pump the fluid from an inlet opening through the rotor assembly to the outlet opening and a bearing assembly for contactless bearing the rotor assembly, wherein the bearing assembly comprises an even number of electromagnetic units arranged around a central structure of the bearing assembly, where the central structure provides a fluid channel towards the rotor assembly, each comprising a first salient established by a magnetic material and a permanent magnet at least magnetically connected to the magnetic material providing a first magnetic pole facing towards the rotor assembly and a coil wound around the first salient, where the bearing assembly further comprises an inter joke comprising inter joke portions connected to the first salient of each electromagnetic unit, where the permanent magnets of adjacent electromagnetic units are suitably arranged to provide a closed first magnetic flux via the first salient and the inter joke portions of both the adjacent electromagnetic units and the rotor assembly, the first magnetic flux applying a first attractive force acting on the rotor assembly for compensating at least present motor and fluid-caused forces at a levitation position of the rotor assembly, the first magnetic flux applying a first additional attractive force further comprising a position stabilizing portion perpendicular to the first attractive force on the rotor-assembly, and the coils providing an electromagnetic flux between each first salient and the rotor assembly for applying adaptable axial force and/or tilting torque to the rotor assembly to keep the rotor within the levitation range during rotation and to compensate the current motor force and fluid caused forces in order to adjust the bearing provided by the first magnetic flux.
Liquid cathode battery comprising: - an anode made of calcium; - an electrolyte comprising a sulphur-containing and/or phosphorous-containing oxidising solvent and at least one salt; - a cathode comprising, as the active material, a compound which is identical to the above-mentioned oxidising solvent, and which comprises a carbon-containing matrix; characterised in that the carbon-containing matrix is a self-supporting matrix which comprises interlaced carbon fibres which have a porosity of at least 90% and a specific surface area equal to or less than 5 m 2 /g. - an anode made of calcium; - an electrolyte comprising a sulphur-containing and/or phosphorous-containing oxidising solvent and at least one salt; - a cathode comprising, as the active material, a compound which is identical to the above-mentioned oxidising solvent, and which comprises a carbon-containing matrix;
Insert designed to be fitted on a support, comprising a body extending along a longitudinal axis and a base comprising at least one plate (15a, 15b) extending along a base plane, the at least one plate (15a, 15b) having first and second opposing surfaces (17, 18) and defining at least one through hole oriented along an orientation axis perpendicular to the base plane and at least one protuberance and at least one hollow being formed on a first surface of said at least one plate (15a, 15b), and the at least one protuberance forms a hollow on a second surface of said at least one plate (15a, 15b), characterized in that at least one protuberance has a form of a tray extending from a central part to an external edge (21a, 21b) of said at least one plate (15a, 15b), the at least one protuberance having a flat portion connecting two angled edges or two sloped edges at an angular distance with respect to the flat portion, the two angled edges or the two sloped edges separating the at least one protuberance and the at least one hollow on the first surface of said at least one plate (15a, 15b).
A method for lamination of a barrier film or sheet to a bulk layer of paper or paperboard or other cellulose-based material, said bulk layer being provided with going-through holes, the method comprising: coating the barrier film or sheet with a wet adhesive, feeding the coated barrier film or sheet to a nip formed between a nip roller and a support roller such that the non-coated side of the barrier film or sheet is in contact with the nip roller, feeding the bulk layer to said nip such that the bulk layer is in contact with the support roller, and feeding the bulk layer and the coated barrier film or sheet through the nip, thereby allowing the bulk layer to adhere to the barrier film or sheet by means of the adhesive, characterized in that the surface material of the nip roller is softer than the surface material of the support roller. coating the barrier film or sheet with a wet adhesive, feeding the coated barrier film or sheet to a nip formed between a nip roller and a support roller such that the non-coated side of the barrier film or sheet is in contact with the nip roller, feeding the bulk layer to said nip such that the bulk layer is in contact with the support roller, and feeding the bulk layer and the coated barrier film or sheet through the nip, thereby allowing the bulk layer to adhere to the barrier film or sheet by means of the adhesive, characterized in that the surface material of the nip roller is softer than the surface material of the support roller.
A method for fusing a first conduit portion to a second conduit portion, wherein at least one of the first conduit portion and the second conduit portion comprises a polyvinyl chloride material, the method comprising the steps of: (a) removably positioning a first terminal edge of the first conduit portion in an opposing relationship with a first terminal edge of the second conduit portion; (b) facing the first terminal edge of the first conduit portion and the first terminal edge of the second conduit portion; (c) aligning the first terminal edge of the first conduit portion with the first terminal edge of the second conduit portion; (d) melting at least a portion of the first terminal edge of the first conduit portion and the first terminal edge of the second conduit portion; (e) engaging the melted terminal edge of the first conduit portion with the melted terminal edge of the second conduit portion at a pressure of about 965 kPa (140 psi); and (f) maintaining pressure between the engaged terminal edge of the first conduit portion and the terminal edge of the second conduit portion, thereby creating a fused joint area. (a) removably positioning a first terminal edge of the first conduit portion in an opposing relationship with a first terminal edge of the second conduit portion; (b) facing the first terminal edge of the first conduit portion and the first terminal edge of the second conduit portion; (c) aligning the first terminal edge of the first conduit portion with the first terminal edge of the second conduit portion; (d) melting at least a portion of the first terminal edge of the first conduit portion and the first terminal edge of the second conduit portion; (e) engaging the melted terminal edge of the first conduit portion with the melted terminal edge of the second conduit portion at a pressure of about 965 kPa (140 psi); and (f) maintaining pressure between the engaged terminal edge of the first conduit portion and the terminal edge of the second conduit portion, thereby creating a fused joint area.
Method for increasing the coercivity of a sintered type NdFeB permanent magnet, the method comprising the following steps: (a) adsorbing a heavy rare earth powder on at least one face of an adhesive organic film whose thickness is in the range of 4 to 50 μm, thus obtaining a heavy rare earth diffusion source comprising at least one uniform layer of the heavy rare earth powder on the adhesive organic film; (b) placing the heavy rare earth diffusion source with its heavy rare earth powder layer on a surface of an NdFeB permanent magnet which extends perpendicular to the magnetization direction of the NdFeB permanent magnet and applying a pressing force; and (c) subjecting the NdFeB permanent magnet coated with the heavy rare earth diffuse source to high temperature diffusion and aging treatment. (a) adsorbing a heavy rare earth powder on at least one face of an adhesive organic film whose thickness is in the range of 4 to 50 μm, thus obtaining a heavy rare earth diffusion source comprising at least one uniform layer of the heavy rare earth powder on the adhesive organic film; (b) placing the heavy rare earth diffusion source with its heavy rare earth powder layer on a surface of an NdFeB permanent magnet which extends perpendicular to the magnetization direction of the NdFeB permanent magnet and applying a pressing force; and (c) subjecting the NdFeB permanent magnet coated with the heavy rare earth diffuse source to high temperature diffusion and aging treatment.
A catheter comprising: an inner layer made of a resin; a braid surrounding an outer periphery of the inner layer, the braid including a plurality of first wires and a plurality of second wires; an outer layer surrounding an outer periphery of the braid, the outer layer being made of a resin; and a distal tip disposed at a distal end of the inner layer, a distal end of the braid, and a distal end of the outer layer, the distal tip being made of a resin, wherein a recessed region (100, 300, 400, 1000) is formed in a distal end portion of the braid, the recessed region (100, 300, 400, 1000) having a recess first side (101, 301, 401) and a recess second side (102, 302, 402), and wherein the distal tip is bonded to the inner layer in the recessed region (100, 300, 400, 1000), characterized in that the recess first side (101, 301, 401) is longer than the sum of a wire width of each of the first wires and a distance between two adjacent first wires among the plurality of the first wires, and the recess second side (102, 302, 402) is longer than the sum of a wire width of each of the second wires and a distance between two adjacent second wires among the plurality of the second wires. an inner layer made of a resin; a braid surrounding an outer periphery of the inner layer, the braid including a plurality of first wires and a plurality of second wires; an outer layer surrounding an outer periphery of the braid, the outer layer being made of a resin; and a distal tip disposed at a distal end of the inner layer, a distal end of the braid, and a distal end of the outer layer, the distal tip being made of a resin, wherein a recessed region (100, 300, 400, 1000) is formed in a distal end portion of the braid, the recessed region (100, 300, 400, 1000) having a recess first side (101, 301, 401) and a recess second side (102, 302, 402), and wherein the distal tip is bonded to the inner layer in the recessed region (100, 300, 400, 1000), characterized in that the recess first side (101, 301, 401) is longer than the sum of a wire width of each of the first wires and a distance between two adjacent first wires among the plurality of the first wires, and the recess second side (102, 302, 402) is longer than the sum of a wire width of each of the second wires and a distance between two adjacent second wires among the plurality of the second wires.
A bar segment for laying out public and/or private spaces, in particular in the sporting field, the segment extending in a direction of extension and comprising: - a main portion; - a first end portion comprising a first assembly element; - a second end portion comprising a second assembly element, complementary to the first assembly element of the first end portion, the first or the second end portion (5,9) being arranged to cooperate with an adjacent segment at an assembly area, each of the first and second assembly elements (7, 11) comprising a support portion (17, 21) and a holding portion (19, 23), characterized in that the main portion, the first end portion and the second end portion are integrally made in one piece. - a main portion; - a first end portion comprising a first assembly element; - a second end portion comprising a second assembly element, complementary to the first assembly element of the first end portion,
Image sensor array for capturing image information for automatic image data processing, having a multiplicity of identical sensor cells, which respectively have an image sensor with a dedicated sensor optical system, a frame buffer for storing image information from the image sensor, and an evaluation unit for processing the image information, the sensor cells being arranged in at least one row such that the capture regions of the image sensors of directly adjacent sensor cells overlap, characterized in that each sensor cell has at least one data interface to an adjacent sensor cell and is configured to access the image data of the overlapping capture region of the adjacent sensor cell via the corresponding data interface, with the evaluation units respectively being configured to determine a correlation of these items of image data.
A charging method comprising: activating a handshake communication between a terminal device and a power supply device through a universal serial bus, USB, interface when, within a preset time period, an output current of the power supply device is higher than or equal to a preset current threshold; determining to charge a battery of the terminal device in a quick charging mode upon receiving, by the power supply device from the terminal device via the handshake communication, an instruction indicating activation of the quick charging mode, wherein the instruction indicating activation of the quick charging mode is generated in response to receiving, from the power supply device, an instruction for querying whether or not the terminal device agrees to activate the quick charging mode via the handshake communication; conducting a handshake communication with the terminal device to determine a charging voltage or a charging current of the quick charging mode; adjusting an output voltage or an output current output to the terminal device according to the charging voltage or the charging current of the quick charging mode to enter a constant current phase; and conducting a handshake communication with the terminal device during the constant current phase to adjust the output current output to the terminal device. activating a handshake communication between a terminal device and a power supply device through a universal serial bus, USB, interface when, within a preset time period, an output current of the power supply device is higher than or equal to a preset current threshold; determining to charge a battery of the terminal device in a quick charging mode upon receiving, by the power supply device from the terminal device via the handshake communication, an instruction indicating activation of the quick charging mode, wherein the instruction indicating activation of the quick charging mode is generated in response to receiving, from the power supply device, an instruction for querying whether or not the terminal device agrees to activate the quick charging mode via the handshake communication; conducting a handshake communication with the terminal device to determine a charging voltage or a charging current of the quick charging mode; adjusting an output voltage or an output current output to the terminal device according to the charging voltage or the charging current of the quick charging mode to enter a constant current phase; and conducting a handshake communication with the terminal device during the constant current phase to adjust the output current output to the terminal device.
A locking carabiner comprising: a body comprising a first end and a second end and defining a chamber; a gate rotatably coupled to the second end about a gate axis, wherein the gate comprises a pivot end and a free end that defines a longitudinal axis; and a locking mechanism rotatably coupled to the gate about a locking mechanism axis, wherein the locking mechanism comprises a lever arm rotatably coupled to the gate at the locking mechanism axis that is between the pivot end and the free end of the gate, wherein the lever arm is partially disposed on an outside of the gate relative to the chamber of the body and extends substantially along the longitudinal axis, wherein the lever arm comprises a free end configured to be positioned proximate the first end in a blocking position so as to engage with the first end and prevent the gate from opening into the chamber of the body, wherein the gate axis is substantially parallel to, and offset from, the locking mechanism axis, and wherein the rotation of the locking mechanism is in a substantially similar plane as the rotation of the gate. a body comprising a first end and a second end and defining a chamber; a gate rotatably coupled to the second end about a gate axis, wherein the gate comprises a pivot end and a free end that defines a longitudinal axis; and a locking mechanism rotatably coupled to the gate about a locking mechanism axis, wherein the locking mechanism comprises a lever arm rotatably coupled to the gate at the locking mechanism axis that is between the pivot end and the free end of the gate, wherein the lever arm is partially disposed on an outside of the gate relative to the chamber of the body and extends substantially along the longitudinal axis, wherein the lever arm comprises a free end configured to be positioned proximate the first end in a blocking position so as to engage with the first end and prevent the gate from opening into the chamber of the body, wherein the gate axis is substantially parallel to, and offset from, the locking mechanism axis, and wherein the rotation of the locking mechanism is in a substantially similar plane as the rotation of the gate.
A device for reducing harmful bearing voltages in an electrical machine fed by a DC link voltage of a DC link, comprising a stator which has windings and is isolated from ground, and a rotor, wherein at least two bearings consisting of an outer bearing ring and an inner bearing ring are provided between the rotor and the stator, and wherein further an electrical connecting arrangement of the stator to a potential which is stable with respect to the DC link is provided, wherein the connecting arrangement of the stator to a potential which is stable with respect to the DC link is established via an impedance or a capacitance (C a), characterized in that the device includes a shielding arrangement which is at least provided between the windings of the stator and the respective outer bearing rings and the shielding arrangement is connected to the stator directly or indirectly via an impedance or a capacitance via an electrical connecting arrangement.