mhurhangee/ep-ind-claims huggingface dataset:
A process for producing a collagenase composition consisting of Clostridium histolyticum collagenase I and Clostridium histolyticum collagenase II, having a mass ratio of about 1 to 1 and purified to at least 95% by area as measured by reverse-phase high performance liquid chromatography, comprising the steps of: a) fermenting Clostridium histolyticum; b) harvesting a crude fermentation comprising collagenase I and collagenase II; c) purifying collagenase I and collagenase II from the crude harvest via filtration and column chromatography; comprising the steps of i) filtering the crude harvest through an anion exchange filter; ii) adding ammonium sulphate; iii) subjecting the harvest through a hydrophobic interaction column; iv) adding leupeptin to the filtrate; v) removing the ammonium sulphate; vi) filtering the harvest from step (v); vii) separating collagenase I and collagenase II using ion-exchange chromatography; and d) combining the collagenase I and collagenase II purified from step (c) at a ratio of about 1 to 1. a) fermenting Clostridium histolyticum; b) harvesting a crude fermentation comprising collagenase I and collagenase II; c) purifying collagenase I and collagenase II from the crude harvest via filtration and column chromatography; comprising the steps of i) filtering the crude harvest through an anion exchange filter; ii) adding ammonium sulphate; iii) subjecting the harvest through a hydrophobic interaction column; iv) adding leupeptin to the filtrate; v) removing the ammonium sulphate; vi) filtering the harvest from step (v); vii) separating collagenase I and collagenase II using ion-exchange chromatography; and i) filtering the crude harvest through an anion exchange filter; ii) adding ammonium sulphate; iii) subjecting the harvest through a hydrophobic interaction column; iv) adding leupeptin to the filtrate; v) removing the ammonium sulphate; vi) filtering the harvest from step (v); vii) separating collagenase I and collagenase II using ion-exchange chromatography; and d) combining the collagenase I and collagenase II purified from step (c) at a ratio of about 1 to 1.
An improved local oscillator driver circuit for a mixer, the local oscillator driver circuit comprising: a gain circuit responsive to local oscillator input signals (INN, INP) at a predetermined local oscillator frequency range; at least a first pair of a parallel combination of a resistor (R DC) and a capacitor (C P) coupled to the gain circuit and to local oscillator inputs of the mixer, the resistor (R DC) configured to increase impedance at low frequencies of the frequency range and the capacitor (C P) configured to reduce the impedance of the parallel combination at high frequencies of the frequency range; and at least a second pair of a parallel combination of a low quality inductor (L LQ) and a high quality inductor (L HQ) connected to the first pair, the second pair in serial combination with the first pair tuned to provide a constant desired load impedance and a constant desired voltage swing at the local oscillator inputs of the mixer over the predetermined local oscillator frequency range. a gain circuit responsive to local oscillator input signals (INN, INP) at a predetermined local oscillator frequency range; at least a first pair of a parallel combination of a resistor (R DC) and a capacitor (C P) coupled to the gain circuit and to local oscillator inputs of the mixer, the resistor (R DC) configured to increase impedance at low frequencies of the frequency range and the capacitor (C P) configured to reduce the impedance of the parallel combination at high frequencies of the frequency range; and at least a second pair of a parallel combination of a low quality inductor (L LQ) and a high quality inductor (L HQ) connected to the first pair, the second pair in serial combination with the first pair tuned to provide a constant desired load impedance and a constant desired voltage swing at the local oscillator inputs of the mixer over the predetermined local oscillator frequency range.
A vending machine with trays, comprising: - a frame with outer walls, - a storage compartment for products to be dispensed, which is contained in said frame, - a pair of mutually opposed side partitions, which directly face said storage compartment, said side partitions enclosing a service space facing away from said storage compartment, - a pair of uprights, located at each side partition, for supporting horizontal guides of trays, characterized in that said uprights directly face said storage compartment, each side partition extending between two uprights without overlapping them, said horizontal guides being attached to said uprights and holding said side partitions between said uprights. - a frame with outer walls, - a storage compartment for products to be dispensed, which is contained in said frame, - a pair of mutually opposed side partitions, which directly face said storage compartment, said side partitions enclosing a service space facing away from said storage compartment, - a pair of uprights, located at each side partition, for supporting horizontal guides of trays,
Method implemented in a computing device to generate a protected secret value k' used as a second operand in a cryptographic group operation involving a base group element G of an order n and comprising: - generating random positive integers k1 and k2, that are strictly smaller than the order of the group element G thanks to a cryptographically secure random number generator, such that the generated random positive integers k1 and k2 do not share any divisor with the order n other than 1, - generating the protected secret value k' based on said generating random positive integers such as k' = k1 ∗ k2, said protected secret value k' being used as the second operand in the group operation, and wherein a secret value k, which is protected by using the protected secret value k' instead of the secret value k in the cryptographic group operation, is obtainable by applying a modular reduction on the generated protected secret value k' modulo the order n of the base element G. - generating random positive integers k1 and k2, that are strictly smaller than the order of the group element G thanks to a cryptographically secure random number generator, such that the generated random positive integers k1 and k2 do not share any divisor with the order n other than 1, - generating the protected secret value k' based on said generating random positive integers such as k' = k1 ∗ k2, said protected secret value k' being used as the second operand in the group operation,
An acetabular guide (200, 200A, 200B, 200C) comprising: a patient-specific engagement surface designed to be complementary and mateable with a corresponding surface of the patient's pelvic anatomy as determined during a pre-operative plan of the patient by a three-dimensional reconstruction of the anatomy of the patient using two-dimensional medical images, the patient-specific engagement surface having a first portion mateable with a portion of an acetabulum of the patient; a guiding element extending from the acetabular guide opposite to the first portion of engagement surface, the guiding element defining a bore designed to be oriented along an alignment axis for an acetabular implant when the acetabular guide is engaged to the acetabulum; first and second marker elements extending from a portion of the acetabular guide outside the acetabulum of the patient, the marker elements defining corresponding first and second bores for guiding first and second marker pins into a bone portion of the patient in combination with a secondary guide (600A, 600B) designed during the pre-operative plan to include first and second secondary marker elements complementary to the first and second marker elements of the acetabular guide for receiving the first and second marker pins when the first and second marker pins are attached to a bone portion of the patient, characterised in that the secondary guide includes a second guiding element, the second guiding element defining a bore designed to be oriented parallel to the alignment axis for the acetabular implant when the secondary guide is engaged to the acetabulum. a patient-specific engagement surface designed to be complementary and mateable with a corresponding surface of the patient's pelvic anatomy as determined during a pre-operative plan of the patient by a three-dimensional reconstruction of the anatomy of the patient using two-dimensional medical images, the patient-specific engagement surface having a first portion mateable with a portion of an acetabulum of the patient; a guiding element extending from the acetabular guide opposite to the first portion of engagement surface, the guiding element defining a bore designed to be oriented along an alignment axis for an acetabular implant when the acetabular guide is engaged to the acetabulum; first and second marker elements extending from a portion of the acetabular guide outside the acetabulum of the patient, the marker elements defining corresponding first and second bores for guiding first and second marker pins into a bone portion of the patient in combination with a secondary guide (600A, 600B) designed during the pre-operative plan to include first and second secondary marker elements complementary to the first and second marker elements of the acetabular guide for receiving the first and second marker pins when the first and second marker pins are attached to a bone portion of the patient, characterised in that the secondary guide includes a second guiding element, the second guiding element defining a bore designed to be oriented parallel to the alignment axis for the acetabular implant when the secondary guide is engaged to the acetabulum.
A corrugated tube with a path-maintaining member comprising: a corrugated tube that has annular convex portions and annular concave portions alternately formed along a longitudinal direction; and a path-maintaining member made of resin that is formed as a long member die-molded to maintain a shape at least a portion of which is bent along the longitudinal direction, that includes an arc-shaped portion in which a lateral-direction cross section exhibits an arc shape, and that is attached to the corrugated tube along the longitudinal direction in a state where the arc-shaped portion is arranged on an inner periphery side of the corrugated tube, characterized in that the path-maintaining member includes a first portion and a second portion that have different dimensions in a width direction of the arc-shaped portion, and the first portion having a long dimension in the width direction of the arc-shaped portion is more sharply bent than the second portion having a short dimension in the width direction of the arc-shaped portion. a corrugated tube that has annular convex portions and annular concave portions alternately formed along a longitudinal direction; and a path-maintaining member made of resin that is formed as a long member die-molded to maintain a shape at least a portion of which is bent along the longitudinal direction, that includes an arc-shaped portion in which a lateral-direction cross section exhibits an arc shape, and that is attached to the corrugated tube along the longitudinal direction in a state where the arc-shaped portion is arranged on an inner periphery side of the corrugated tube, characterized in that the path-maintaining member includes a first portion and a second portion that have different dimensions in a width direction of the arc-shaped portion, and the first portion having a long dimension in the width direction of the arc-shaped portion is more sharply bent than the second portion having a short dimension in the width direction of the arc-shaped portion.
A method for operating a display apparatus for a motor vehicle comprising a plurality of a display surfaces (36, 38), wherein a plurality of non-contact inputs actions are provided, in which - in order to select at least one display element on a first display surface, a first non-contact input action of a user is detected, and the first non-contact input action is verified by a second non-contact input action of the user; and - in order to move, at least once, the at least one selected display element of the first display surface within the first display surface or onto a second display surface, at least one third non-contact input action of the user is detected, wherein, in order to detect the first non-contact input action, at least one eye position of the user is detected by a first camera, and for verification a variable that is characteristic of the torso of the user is detected by a second camera as the second non-contact input action, or in order to detect the first non-contact input action, at least one variable that is characteristic of the torso of the user is detected by the second camera, and for verification at least the eye position of the user is detected by the first camera as the second non-contact input action, and in order to detect the third touch-sensitive input action, at least one variable that is characteristic of the hand, the finger(s) and/or the mouth of the user is detected by a third camera for detecting gestures. - in order to select at least one display element on a first display surface, a first non-contact input action of a user is detected, and the first non-contact input action is verified by a second non-contact input action of the user; and - in order to move, at least once, the at least one selected display element of the first display surface within the first display surface or onto a second display surface, at least one third non-contact input action of the user is detected, wherein, in order to detect the first non-contact input action, at least one eye position of the user is detected by a first camera, and for verification a variable that is characteristic of the torso of the user is detected by a second camera as the second non-contact input action, or in order to detect the first non-contact input action, at least one variable that is characteristic of the torso of the user is detected by the second camera, and for verification at least the eye position of the user is detected by the first camera as the second non-contact input action, and in order to detect the third touch-sensitive input action, at least one variable that is characteristic of the hand, the finger(s) and/or the mouth of the user is detected by a third camera for detecting gestures.
A flexographic relief image printing element comprising at least one photopolymer layer on a backing layer, wherein the at least one photopolymer layer comprises a cured floor layer therein and wherein the cured floor layer establishes an overall depth of plate relief; wherein the at least one photopolymer layer comprises a plurality of dots in relief, wherein said plurality of dots comprise the following characteristics: the shoulder angle of the dot is such that θ 1 is greater than 70° and θ 2 is less than 45°; and the dot reliefs of the printing element are greater than 9% of the overall plate relief.
A capacitor comprising: a first bar and a second bar; a first plurality of conductive digits extending from the first bar; a second plurality of conductive digits extending from the second bar and positioned in an interlocking manner with the first plurality of conductive digits such that an interdigitated structure is formed; wherein the first bar has a first feeding point deployed on the first bar for providing current to the first plurality of conductive digits, wherein a first subset of the first plurality of conductive digits that is positioned closest to the first feeding point has widths that are wider than a second subset of the first plurality of conductive digits that is positioned farthest away from the first feeding point; and wherein the second bar has a second feeding point deployed on the second bar for providing current to the second plurality of conductive digits, wherein a first subset of the second plurality of conductive digits that is positioned closest to the second feeding point has widths that are wider than a second subset of the second plurality of conductive digits that is positioned farthest away from the second feeding point; characterized in that gaps between adjacent digits in the interdigitated structure are substantially uniform. a first bar and a second bar; a first plurality of conductive digits extending from the first bar; a second plurality of conductive digits extending from the second bar and positioned in an interlocking manner with the first plurality of conductive digits such that an interdigitated structure is formed; wherein the first bar has a first feeding point deployed on the first bar for providing current to the first plurality of conductive digits, wherein a first subset of the first plurality of conductive digits that is positioned closest to the first feeding point has widths that are wider than a second subset of the first plurality of conductive digits that is positioned farthest away from the first feeding point; and wherein the second bar has a second feeding point deployed on the second bar for providing current to the second plurality of conductive digits, wherein a first subset of the second plurality of conductive digits that is positioned closest to the second feeding point has widths that are wider than a second subset of the second plurality of conductive digits that is positioned farthest away from the second feeding point; characterized in that gaps between adjacent digits in the interdigitated structure are substantially uniform.
An implantable medical device system, comprising: a first device comprising a sensing module coupled to a plurality of electrodes (24, 28, 30) implanted outside the cardiovascular system of a patient and carried by an extravascular lead extending from the first device, the first device configured to: receive by the sensing module a first cardiac signal using a first pair of electrodes of the plurality of electrodes, and characterised by the first pair of the plurality of electrodes defining at least a first sensing vector that is aligned with an axis having the greatest P-wave amplitude; generate a first electrocardiogram signal based on the first cardiac signal; identify a P-wave using the first ECG signal; a trigger signal emitting device controlled by the first device to emit a wireless trigger signal in response to the identified P-wave; and an intracardiac pacemaker configured to detect the wireless trigger signal and deliver a pacing therapy in response to the wireless trigger signal. a first device comprising a sensing module coupled to a plurality of electrodes (24, 28, 30) implanted outside the cardiovascular system of a patient and carried by an extravascular lead extending from the first device, the first device configured to: receive by the sensing module a first cardiac signal using a first pair of electrodes of the plurality of electrodes, and characterised by the first pair of the plurality of electrodes defining at least a first sensing vector that is aligned with an axis having the greatest P-wave amplitude; generate a first electrocardiogram signal based on the first cardiac signal; identify a P-wave using the first ECG signal; receive by the sensing module a first cardiac signal using a first pair of electrodes of the plurality of electrodes, and characterised by the first pair of the plurality of electrodes defining at least a first sensing vector that is aligned with an axis having the greatest P-wave amplitude; generate a first electrocardiogram signal based on the first cardiac signal; identify a P-wave using the first ECG signal; a trigger signal emitting device controlled by the first device to emit a wireless trigger signal in response to the identified P-wave; and an intracardiac pacemaker configured to detect the wireless trigger signal and deliver a pacing therapy in response to the wireless trigger signal.
Tank, especially a high security tank, preferably for accumulation and storage of a cryogenic medium, comprising a container with an opening and comprising a cover for closing the opening, characterized by a flexible unipartite cladding which bears against an inside and an outside of the container and which is folded over at the opening, wherein the cladding is stocking-liked, wherein the closed end of the cladding bears against the inside or outside of the container.
A multicellular lay-up process, the process comprising the steps of: a) forming a core material, b) forming a capsule material, c) encapsulating the core with the capsule material, d) adding the capsule to a substrate, and e) exposing the capsule to at least one bioactivating agent, the multicellular lay-up process being characterised in that the capsule material comprises a water soluble polymer, a fibrous component, and a solvent, and wherein the core comprises one or more mammalian cells, cell culture medium and a hydrogel. a) forming a core material, b) forming a capsule material, c) encapsulating the core with the capsule material, d) adding the capsule to a substrate, and e) exposing the capsule to at least one bioactivating agent,
A method for transferring medical data from a wireless sensor to a health information system, the method comprising receiving medical data from the wireless sensor, determining an identity of the wireless sensor, determining a nature of the received medical data; and transmitting the received medical data to the health information system subsequent to determining the nature of the received medical data, characterized in that the method is for transferring medical data from a wireless sensor to a health information system using a patient support apparatus in that the method comprises wirelessly transferring, with the patient support apparatus, a supply of power to the wireless sensor to initiate operation of the wireless sensor, the medical data from the wireless sensor being received with the patient support apparatus while wirelessly transferring the supply of power to the wireless sensor, the identity of the wireless sensor being determined on the patient support apparatus, and the nature of the received medical data being determined with the patient support apparatus; in that the method further comprises associating the received medical data with the patient support apparatus, and in that the received medical data and data identifying the associated patient support apparatus are transmitted from the patient support apparatus to the health information system in response to determining the nature of the received medical data.
An animal waste collecting device comprising a disposable container, a resilient sleeve for retaining said disposable container, and a releasable attachment means (23, 24, 25) for releasably attaching said disposable container with respect to said resilient sleeve; said resilient sleeve comprising at least two oppositely disposed walls (1, 2); said resilient sleeve and said disposable container having at least one openable end which is openable by compressing said device to reveal an opening for insertion of animal waste into said disposable container; the resilient sleeve tending to close onto said animal waste, when compression is no longer applied, in order to retain both said animal waste and said disposable container with respect to said sleeve; wherein said releasable attachment means are configured to allow said disposable container and its contents to be released from said collecting device, wherein said sleeve comprises two openings (39, 40); one located at a first extremity of the collecting device through which, in use, animal waste may be inserted into the disposable container; and a second opening ocated at the opposite extremity to the first extremity, through which the disposable container with animal waste, if any, may exit the device, characterised in that said releasable attachment means comprises a flexible band which releasably secures at least a portion of said disposable container to said resilient sleeve, wherein said oppositely disposed walls (1, 2) form a substantially flat sleeve, when no compression is applied, said walls being hinged along a first lateral edge and being releasably secured along a second lateral edge.