A compound according to Formula I-1: wherein: Ring A is a monocyclic ring formed by an alkylene group taken together with the C=C of the pyrazolyl to which Ring A is fused, wherein 1, 2, or 3 carbon atoms of the alkylene group are optionally replaced with a heteroatom selected from O, N or S, and Ring A is optionally substituted with one to three substituents independently selected from R 3, wherein R 3 is selected from the group consisting of OH, oxo, (C 1-4)alkyl, -(C 1-4)alkylene-N(R a) 2, -(C 1-4)alkylene-(C 3-6 cycloalkyl), (C 1-4)alkoxy, N(R a) 2, N(R 6)CO 2 R 7, N(R 6)C R 8, C R 8, C N(R 8) 2, wherein said alkyl is optionally substituted with one or more halogen or hydroxyl; Z is C or CH 2; m is 0, 1, or 2; n is 1, 2 or 3; R 1 is independently OH, halogen, (C 1-4)alkyl, CN, CF 3, or CHF 2, wherein said alkyl is optionally substituted with one or more halogen; R 2 is independently halogen, (C 1-4)alkyl, CF 3, CHF 2, or (C 3-4)cycloalkyl, wherein said alkyl and cycloalkyl are optionally substituted with one or more substituents independently selected from the group consisting of CN, (C 1-4)haloalkyl, and halogen; Rs is independently OH, (C 0-4)alkyl, or S 2 R b; R 6 is independently (C 0-4)a|ky|; R 7 is independently (C 1-6)alkyl; R 8 is independently OH, (C 0-4)alkyl, 2-8 membered heteroalkyl, or one of the following: a heterocyclyl-containing group selected from 3-10 membered heterocyclyl, -C 1-6 alkylene-(5-6 membered heteroaryl), -O-(C 1-6 alkylene)-(5-6 membered heteroaryl), or -(3-10 membered heterocycloalkylene)-(3-10 membered heterocycloalkyl), each optionally substituted by one or more Rg; a carbocyclyl-containing group selected from C 3-7 carbocyclyl, -C 1-6 alkylene-(C 3-7 carbocyclyl), -O-C 3-7 carbocyclyl, or -O-(C 1-6 alkylene)-C 3-7 carbocyclyl, each optionally substituted by one or more Rg; R 9 is independently halogen, hydroxyl, (C 1-4)alkyl, (C 1-4)haloalkyl, (C 1-6)alkoxyl, N(R a) 2, (C 3-4)cycloalkyl, or cyano, wherein said cycloalkyl is optionally substituted with one or more substituents independently selected from the group consisting of CN, (C 1-4)haloalkyl, and halogen; R a is independently (C 0-4)alkyl, (C 1-4) haloalkyl, or 3-7 membered heterocycloalkyl; and R b is (C 1-4)alkyl; or a pharmaceutically acceptable salt thereof. Ring A is a monocyclic ring formed by an alkylene group taken together with the C=C of the pyrazolyl to which Ring A is fused, wherein 1, 2, or 3 carbon atoms of the alkylene group are optionally replaced with a heteroatom selected from O, N or S, and Ring A is optionally substituted with one to three substituents independently selected from R 3, wherein R 3 is selected from the group consisting of OH, oxo, (C 1-4)alkyl, -(C 1-4)alkylene-N(R a) 2, -(C 1-4)alkylene-(C 3-6 cycloalkyl), (C 1-4)alkoxy, N(R a) 2, N(R 6)CO 2 R 7, N(R 6)C R 8, C R 8, C N(R 8) 2, wherein said alkyl is optionally substituted with one or more halogen or hydroxyl; Z is C or CH 2; m is 0, 1, or 2; n is 1, 2 or 3; R 1 is independently OH, halogen, (C 1-4)alkyl, CN, CF 3, or CHF 2, wherein said alkyl is optionally substituted with one or more halogen; R 2 is independently halogen, (C 1-4)alkyl, CF 3, CHF 2, or (C 3-4)cycloalkyl, wherein said alkyl and cycloalkyl are optionally substituted with one or more substituents independently selected from the group consisting of CN, (C 1-4)haloalkyl, and halogen; Rs is independently OH, (C 0-4)alkyl, or S 2 R b; R 6 is independently (C 0-4)a|ky|; R 7 is independently (C 1-6)alkyl; R 8 is independently OH, (C 0-4)alkyl, 2-8 membered heteroalkyl, or one of the following: a heterocyclyl-containing group selected from 3-10 membered heterocyclyl, -C 1-6 alkylene-(5-6 membered heteroaryl), -O-(C 1-6 alkylene)-(5-6 membered heteroaryl), or -(3-10 membered heterocycloalkylene)-(3-10 membered heterocycloalkyl), each optionally substituted by one or more Rg; a carbocyclyl-containing group selected from C 3-7 carbocyclyl, -C 1-6 alkylene-(C 3-7 carbocyclyl), -O-C 3-7 carbocyclyl, or -O-(C 1-6 alkylene)-C 3-7 carbocyclyl, each optionally substituted by one or more Rg; a heterocyclyl-containing group selected from 3-10 membered heterocyclyl, -C 1-6 alkylene-(5-6 membered heteroaryl), -O-(C 1-6 alkylene)-(5-6 membered heteroaryl), or -(3-10 membered heterocycloalkylene)-(3-10 membered heterocycloalkyl), each optionally substituted by one or more Rg; a carbocyclyl-containing group selected from C 3-7 carbocyclyl, -C 1-6 alkylene-(C 3-7 carbocyclyl), -O-C 3-7 carbocyclyl, or -O-(C 1-6 alkylene)-C 3-7 carbocyclyl, each optionally substituted by one or more Rg; R 9 is independently halogen, hydroxyl, (C 1-4)alkyl, (C 1-4)haloalkyl, (C 1-6)alkoxyl, N(R a) 2, (C 3-4)cycloalkyl, or cyano, wherein said cycloalkyl is optionally substituted with one or more substituents independently selected from the group consisting of CN, (C 1-4)haloalkyl, and halogen; R a is independently (C 0-4)alkyl, (C 1-4) haloalkyl, or 3-7 membered heterocycloalkyl; and R b is (C 1-4)alkyl;