A tissue clipping apparatus, comprising: a flexible, elongate member, a proximal end of which remains external to the body accessible to a user while a distal end of the flexible member is inserted into the body to a location adjacent to target tissue to be clipped, a control wire extending through the flexible member; a releasable capsule at a distal end of the flexible member; a clip, a proximal portion of which is received within the capsule, the clip including a plurality of arms, each of the arms including a shoulder which, when the clip is withdrawn proximally into the capsule engages with the capsule to define a maximum extent to which the clip may be withdrawn proximally into the capsule; and a joint arrangement releasably coupling the clip to the control wire, characterized by: the joint arrangement including a yoke that is coupled to the clip, the control wire being operable to move the clip repeatedly between an open configuration in which distal ends of the arms of the clip are separated from one another and a closed configuration in which the distal ends of the arms of the clip are drawn together to grasp tissue position therebetween, the joint failing when the clip is drawn into the capsule and prevented from being drawn further into the capsule from the shoulder of the arms of the clip engaging a distal end of the capsule such that the control wire being moved beyond a release point enables a predetermined force to be applied, the joint arrangement further including a clevis that is coupled to the control wire, the yoke and clevis coupled to one another via a frangible link which fails when subject to the predetermined force to separate the clip from the control wire. a flexible, elongate member, a proximal end of which remains external to the body accessible to a user while a distal end of the flexible member is inserted into the body to a location adjacent to target tissue to be clipped, a control wire extending through the flexible member; a releasable capsule at a distal end of the flexible member; a clip, a proximal portion of which is received within the capsule, the clip including a plurality of arms, each of the arms including a shoulder which, when the clip is withdrawn proximally into the capsule engages with the capsule to define a maximum extent to which the clip may be withdrawn proximally into the capsule; and a joint arrangement releasably coupling the clip to the control wire, characterized by: the joint arrangement including a yoke that is coupled to the clip, the control wire being operable to move the clip repeatedly between an open configuration in which distal ends of the arms of the clip are separated from one another and a closed configuration in which the distal ends of the arms of the clip are drawn together to grasp tissue position therebetween, the joint failing when the clip is drawn into the capsule and prevented from being drawn further into the capsule from the shoulder of the arms of the clip engaging a distal end of the capsule such that the control wire being moved beyond a release point enables a predetermined force to be applied, the joint arrangement further including a clevis that is coupled to the control wire, the yoke and clevis coupled to one another via a frangible link which fails when subject to the predetermined force to separate the clip from the control wire. the joint arrangement including a yoke that is coupled to the clip, the control wire being operable to move the clip repeatedly between an open configuration in which distal ends of the arms of the clip are separated from one another and a closed configuration in which the distal ends of the arms of the clip are drawn together to grasp tissue position therebetween, the joint failing when the clip is drawn into the capsule and prevented from being drawn further into the capsule from the shoulder of the arms of the clip engaging a distal end of the capsule such that the control wire being moved beyond a release point enables a predetermined force to be applied, the joint arrangement further including a clevis that is coupled to the control wire, the yoke and clevis coupled to one another via a frangible link which fails when subject to the predetermined force to separate the clip from the control wire.