mhurhangee/ep-ind-claims huggingface dataset:
A system for projecting boresighted synthetic vision images of external surroundings in a helicopter comprising: - one or more sensors; - a terrain database comprising terrain information comprising natural terrain features, vegetation and manmade structures, - a projected synthetic vision controller coupled to the one or more sensors and the terrain database, the projected synthetic vision controller being configured to: - generate synthetic vision images of the external surroundings based on a position of the helicopter and the terrain information of the database, the images showing the terrain information that would be visible to a helicopter operator in a window of the helicopter, and being configured to - boresight the synthetic vision images to an eyesight level of the helicopter operator out of the helicopter; and the system further comprising - one or more projectors coupled to the projected synthetic vision controller, the one or more projectors being configured to project the boresighted synthetic vision images of the external surroundings onto a diffractive holographic member provided on a surface of the window of the helicopter. - one or more sensors; - a terrain database comprising terrain information comprising natural terrain features, vegetation and manmade structures, - a projected synthetic vision controller coupled to the one or more sensors and the terrain database, - generate synthetic vision images of the external surroundings based on a position of the helicopter and the terrain information of the database, the images showing the terrain information that would be visible to a helicopter operator in a window of the helicopter, and being configured to - boresight the synthetic vision images to an eyesight level of the helicopter operator out of the helicopter; and the system further comprising - one or more projectors coupled to the projected synthetic vision controller, the one or more projectors being configured to project the boresighted synthetic vision images of the external surroundings onto a diffractive holographic member provided on a surface of the window of the helicopter.
A method for supplementing media assets during fast-access playback operations, the method comprising: receiving a user input while a media asset is subject to a fast-access playback operation; determining a progression point in the media asset when the user input was received; determining supplemental content including a textual summary of a portion of the media asset that has been subjected to the fast-access playback operation; and generating for presentation, while the media asset continues to be subject to the fast-access playback operation, the textual summary of a portion of the media asset that has been subjected to the fast-access playback operation. receiving a user input while a media asset is subject to a fast-access playback operation; determining a progression point in the media asset when the user input was received; determining supplemental content including a textual summary of a portion of the media asset that has been subjected to the fast-access playback operation; and generating for presentation, while the media asset continues to be subject to the fast-access playback operation, the textual summary of a portion of the media asset that has been subjected to the fast-access playback operation.
T cells transduced to express a chimeric antigen receptor (CAR T cells) for use in a method of treating cancer in a patient, wherein the method comprises the infusion of said CAR T cells to the patient and the administration of a cytokine inhibitor to manage the toxicity resulting from the infusion of CAR T cells, wherein the cytokine inhibitor is an IL-6 inhibitor.
A method for predicting a therapeutic effect of chemotherapy that uses an antitumor agent comprising α,α,α-trifluorothymidine and 5-chloro-6-(1-(2-iminopyrrolidinyl)methyl)uracil hydrochloride at a molar ratio of 1:0.5 on a colorectal cancer patient, the method comprising the steps of: detecting the presence or absence of KRAS gene mutation in a biological sample obtained from the patient; and predicting that the patient is likely to sufficiently respond to the chemotherapy, when KRAS gene mutation is detected in Step. detecting the presence or absence of KRAS gene mutation in a biological sample obtained from the patient; and predicting that the patient is likely to sufficiently respond to the chemotherapy, when KRAS gene mutation is detected in Step.
A surgical apparatus comprising: a mechanism that is configured to perform an operational motion of the surgical apparatus, the mechanism including two or more parts; and at least one transformation member having an original shape and a deformed shape, the at least one transformation member connecting two or more parts of the mechanism together, when the at least one transformation member is in the deformed shape so that the mechanism is capable of performing the operational motion; and wherein after the transformation member is subjected to a transition temperature, the at least one transformation member disengages the two or more parts of the mechanism so that the mechanism is prevented from performing the operational motion. a mechanism that is configured to perform an operational motion of the surgical apparatus, the mechanism including two or more parts; and at least one transformation member having an original shape and a deformed shape, the at least one transformation member connecting two or more parts of the mechanism together, when the at least one transformation member is in the deformed shape so that the mechanism is capable of performing the operational motion; and wherein after the transformation member is subjected to a transition temperature, the at least one transformation member disengages the two or more parts of the mechanism so that the mechanism is prevented from performing the operational motion.
A method for predicting an increased risk of non-alcoholic fatty liver disease (NAFLD) in an individual which comprises the stage of genotyping SNP rs12603226 carried out on a nucleic acid obtained from a biological sample from the individual and in which the presence of allelic homozigosity TT indicates an increased risk of the development of NAFLD.
A system for detecting a target nucleic acid in a sample, the system comprising (a) an electroconductive substrate; (b) a sensing unit that is bound to the substrate, wherein the sensing unit comprises (i) a redox current reporter, and (ii) a sequence-specific nucleic acid sufficiently complementary to that of the target nucleic acid or a sequence therein to specifically bind the target nucleic acid, wherein the redox current reporter is linked to the sequence-specific nucleic acid; (c) inert thiols that are bound to the substrate; and (d) a coreactant. (a) an electroconductive substrate; (b) a sensing unit that is bound to the substrate, wherein the sensing unit comprises (i) a redox current reporter, and (ii) a sequence-specific nucleic acid sufficiently complementary to that of the target nucleic acid or a sequence therein to specifically bind the target nucleic acid, wherein the redox current reporter is linked to the sequence-specific nucleic acid; (i) a redox current reporter, and (ii) a sequence-specific nucleic acid sufficiently complementary to that of the target nucleic acid or a sequence therein to specifically bind the target nucleic acid, (c) inert thiols that are bound to the substrate; and (d) a coreactant.
Seat attachment device, in particular flight passenger seat attachment device, for movably fixating an object to a seat, with a support arm piece, with an apparatus-accommodating piece for fixating the object, with an intermediate piece for coupling the apparatus-accommodating piece to the support arm piece, and with at least one first articulation arranged between the support arm piece and the intermediate piece and comprising a first articulation axis, and with at least one second articulation arranged between the intermediate piece and the apparatus-accommodating piece and comprising a second articulation axis, the intermediate piece providing an offset which offsets the first articulation axis of the first articulation and the second articulation axis of the second articulation with respect to each other in at least one projection direction, wherein the two articulation axes do not share an intersection point, characterised in that the apparatus-accommodating piece has a main extension direction which is oriented axially parallel to the second articulation axis of the second articulation.
A biodegradable film, the film comprising: from 1 wt.% to 49 wt. % by weight of the film of at least one biodegradable polyester; and from 46 wt.% to 75 wt.% by weight of the film of a thermoplastic oxidized starch comprising at least one oxidized corn or wheat starch and at least one plasticizer; wherein the wt.% by weight of the film of the biodegradable polyester is less than the wt.% by weight of the film of the thermoplastic oxidized starch; wherein the biodegradability of the film and the polyester are determined according to ASTM Test Method 5338.92. from 1 wt.% to 49 wt. % by weight of the film of at least one biodegradable polyester; and from 46 wt.% to 75 wt.% by weight of the film of a thermoplastic oxidized starch comprising at least one oxidized corn or wheat starch and at least one plasticizer; wherein the wt.% by weight of the film of the biodegradable polyester is less than the wt.% by weight of the film of the thermoplastic oxidized starch; wherein the biodegradability of the film and the polyester are determined according to ASTM Test Method 5338.92.
A filter cartridge, suitable for crankcase ventilation, comprising: (a) first and second, opposite, end members (540, 541); and, (b) filter media: positioned between the first and second, opposite, end members (540, 541); surrounding an open filter Interior; and, the media surrounds a media central longitudinal axis; (c) the first end member comprising an upper member having an aperture therethrough and including a seal member therearound; characterized by (d) the second member being closed and including a closed receiver projection thereon projecting toward the first end member at least 5% of a distance between opposite ends (535u, 535l) of the media; (i) the receiver projection being offset from the central longitudinal axis. (a) first and second, opposite, end members (540, 541); and, (b) filter media: positioned between the first and second, opposite, end members (540, 541); surrounding an open filter Interior; and, the media surrounds a media central longitudinal axis; (c) the first end member comprising an upper member having an aperture therethrough and including a seal member therearound; characterized by (d) the second member being closed and including a closed receiver projection thereon projecting toward the first end member at least 5% of a distance between opposite ends (535u, 535l) of the media; (i) the receiver projection being offset from the central longitudinal axis. (i) the receiver projection being offset from the central longitudinal axis.
An implant comprising a magnesium alloy having improved mechanical and electromechanical properties, which comprises: no more than 3% by weight of Zn, no more than 0.6% by weight of Ca, with the rest being formed by magnesium containing impurities, which favor electrochemical potential differences and/or promote the formation of intermetallic phases, in a total amount of no more than 0.005% by weight of Fe, Si, Mn, Co, Ni, Cu, Al, Zr and P, wherein the alloy contains elements selected from the group of rare earths with the atomic number 21, 39, 57 to 71 and 89 to 103 in a total amount of no more than 0.002% by weight, Wherein the content of Zn is 0.1 to 1.6% by weight and the content of Ca is 0.001 to 0.5% by weight, Wherein the ratio of the content of Zn to the content of Ca is no more than 3, wherein the alloy in each case contains an intermetallic phase Ca 2 Mg 6 Zn 3 and/or Mg 2 Ca in a volume fraction of close to 0 to 2%, and the phase MgZn is avoided, wherein Zr is no more than 0.0003% by weight, wherein the intermetallic phases are brought to precipitation, the precipitates have a size of no more than 2.0 μm.
A waveguide type slot array antenna device, comprising: a radiator for radiating an electromagnetic wave in a radiating direction; and two dielectric bodies (16, 17, 18, 19) arranged on an electromagnetic wave radiating side of the radiator, said two dielectric bodies facing each other in a vertical direction at a predetermined distance so that the electromagnetic wave passes therebetween, characterized in that: said two dielectric bodies (16, 17, 18, 19) each comprises a plurality of dielectric members arrayed in a longitudinal direction which is horizontal, and perpendicular to the radiating direction of the radiator; and boundaries between the plurality of adjacent dielectric members are asymmetric with respect to a virtual line perpendicularly passing through a center of the dielectric body in the longitudinal direction. a radiator for radiating an electromagnetic wave in a radiating direction; and two dielectric bodies (16, 17, 18, 19) arranged on an electromagnetic wave radiating side of the radiator, said two dielectric bodies facing each other in a vertical direction at a predetermined distance so that the electromagnetic wave passes therebetween, characterized in that: said two dielectric bodies (16, 17, 18, 19) each comprises a plurality of dielectric members arrayed in a longitudinal direction which is horizontal, and perpendicular to the radiating direction of the radiator; and boundaries between the plurality of adjacent dielectric members are asymmetric with respect to a virtual line perpendicularly passing through a center of the dielectric body in the longitudinal direction. said two dielectric bodies (16, 17, 18, 19) each comprises a plurality of dielectric members arrayed in a longitudinal direction which is horizontal, and perpendicular to the radiating direction of the radiator; and boundaries between the plurality of adjacent dielectric members are asymmetric with respect to a virtual line perpendicularly passing through a center of the dielectric body in the longitudinal direction.
An isolated Pseudomonas exotoxin A ("PE"), wherein said PE has residues 1-273 and 285-394 removed and substitutions of alanine, glycine or serine in place of amino acid residues D406 and Q592 corresponding to an amino acid residue of SEQ ID NO:1.
Chain lock comprising two lock halves, wherein each lock half is formed from an elongate body having an end-side coupling section, relative to which a locking pin protrudes and on the side of the body opposite the locking pin a protruding cam is arranged, wherein the cam of a lock half positively engages in a pocket on the locking pin of the opposite lock half, wherein tensile forces engaging with the chain lock may be introduced via the cam into the pocket of the respective other lock half, characterised in that an undercut is formed in the pocket.
Single point mooring wind turbine comprising a rotor arranged on a tower, the wind turbine having a floating foundation with at least two buoyancy bodies (40a, 40b, 40c) arranged in one plane, characterized by a design counteracting the swaying-at-anchor of the wind turbine caused by the rotor torque, wherein: - the tower is inclined relative to the foundation against the direction of rotation of the rotor; or - the wind turbine has, on the side opposite to the direction of rotation of the rotor, a weight which at least partially compensates for the nominal torque of the rotor; or - the buoyancy body arranged in the direction of rotation of the rotor has a greater buoyancy than the buoyancy body arranged opposite the direction of rotation. - the tower is inclined relative to the foundation against the direction of rotation of the rotor; or - the wind turbine has, on the side opposite to the direction of rotation of the rotor, a weight which at least partially compensates for the nominal torque of the rotor; or - the buoyancy body arranged in the direction of rotation of the rotor has a greater buoyancy than the buoyancy body arranged opposite the direction of rotation.
An electronic device comprising: a display; an input module configured to receive a user input; and a processor configured to: execute an application on a first layer having a first area; set a second layer having a second area, the second layer being above the first layer; output the first layer and the second layer on the display, the second layer at least partially overlapping on the first layer; and if the user input is received in the second area and satisfies a given condition, execute a pre-defined function corresponding to the given condition, if the user input is received in the second area and does not satisfy the given condition, processing the user input with respect to the application on the first layer, characterized in that the given condition is based on an input pattern. a display; an input module configured to receive a user input; and a processor configured to: execute an application on a first layer having a first area; set a second layer having a second area, the second layer being above the first layer; output the first layer and the second layer on the display, the second layer at least partially overlapping on the first layer; and execute an application on a first layer having a first area; set a second layer having a second area, the second layer being above the first layer; output the first layer and the second layer on the display, the second layer at least partially overlapping on the first layer; and if the user input is received in the second area and satisfies a given condition, execute a pre-defined function corresponding to the given condition, if the user input is received in the second area and does not satisfy the given condition, processing the user input with respect to the application on the first layer, characterized in that the given condition is based on an input pattern.
An isolated antibody which specifically binds to interleukin-7 receptor alpha (IL-7Rα), wherein the antibody binds to an epitope comprising residues 182, K84, K100, T105, and Y192 of human interleukin-7 receptor alpha (IL-7Rα), and wherein the antibody comprises: a light chain variable region comprising a VL CDR1 having the amino acid sequence shown in SEQ ID NO:29, a VL CDR2 having the amino acid sequence shown in SEQ ID NO:31, and a VL CDR3 having the amino acid sequence shown in SEQ ID NO:36; and one of: (i) a heavy chain variable region comprising a VH CDR1 having the amino acid sequence shown in SEQ ID NO:19, a VH CDR2 having the amino acid sequence shown in SEQ ID NO:23, and a VH CDR3 having the amino acid sequence shown in SEQ ID NO:28; or (ii) a heavy chain variable region comprising a VH CDR1 having the amino acid sequence shown in SEQ ID NO:46, a VH CDR2 having the amino acid sequence shown in SEQ ID NO:48, and a VH CDR3 having the amino acid sequence shown in SEQ ID NO:49; or (iii) a heavy chain variable region comprising a VH CDR1 having the amino acid sequence shown in SEQ ID NO:47, a VH CDR2 having the amino acid sequence shown in SEQ ID NO:23, and a VH CDR3 having the amino acid sequence shown in SEQ ID NO:49, wherein the binding affinity of the antibody to human IL-7R is less than 500pM. a light chain variable region comprising a VL CDR1 having the amino acid sequence shown in SEQ ID NO:29, a VL CDR2 having the amino acid sequence shown in SEQ ID NO:31, and a VL CDR3 having the amino acid sequence shown in SEQ ID NO:36; and one of: (i) a heavy chain variable region comprising a VH CDR1 having the amino acid sequence shown in SEQ ID NO:19, a VH CDR2 having the amino acid sequence shown in SEQ ID NO:23, and a VH CDR3 having the amino acid sequence shown in SEQ ID NO:28; or (ii) a heavy chain variable region comprising a VH CDR1 having the amino acid sequence shown in SEQ ID NO:46, a VH CDR2 having the amino acid sequence shown in SEQ ID NO:48, and a VH CDR3 having the amino acid sequence shown in SEQ ID NO:49; or (iii) a heavy chain variable region comprising a VH CDR1 having the amino acid sequence shown in SEQ ID NO:47, a VH CDR2 having the amino acid sequence shown in SEQ ID NO:23, and a VH CDR3 having the amino acid sequence shown in SEQ ID NO:49, (i) a heavy chain variable region comprising a VH CDR1 having the amino acid sequence shown in SEQ ID NO:19, a VH CDR2 having the amino acid sequence shown in SEQ ID NO:23, and a VH CDR3 having the amino acid sequence shown in SEQ ID NO:28; or (ii) a heavy chain variable region comprising a VH CDR1 having the amino acid sequence shown in SEQ ID NO:46, a VH CDR2 having the amino acid sequence shown in SEQ ID NO:48, and a VH CDR3 having the amino acid sequence shown in SEQ ID NO:49; or (iii) a heavy chain variable region comprising a VH CDR1 having the amino acid sequence shown in SEQ ID NO:47, a VH CDR2 having the amino acid sequence shown in SEQ ID NO:23, and a VH CDR3 having the amino acid sequence shown in SEQ ID NO:49, wherein the binding affinity of the antibody to human IL-7R is less than 500pM.
A chewing gum consisting of at least a first region with gum base and at least a second fully water-soluble region without gum base, said gum being characterized by the presence of a synergic combination of: a) an effective amount of vegetable extracts selected from magnolia bark extract, green tea extract and combinations thereof, b) an effective amount of zinc ions, at least partly contained in fully water-soluble microgranules. a) an effective amount of vegetable extracts selected from magnolia bark extract, green tea extract and combinations thereof, b) an effective amount of zinc ions, at least partly contained in fully water-soluble microgranules.
Sheet-fed printing press comprising a dryer that dries sheets printed by a non-impact printing device, the dryer being configured as a hot air dryer and/or as a dryer that dries by IR radiation, a cooling unit being arranged directly downstream from the dryer in a transport direction of the sheets, the cooling unit comprising at least one cooling module above a conveying plane in which the sheets are conveyed through the cooling unit lying flat, and the relevant cooling module being configured so as to use air as the cooling medium, characterized in that each of the cooling modules of the cooling unit is configured in each case as a blower module, the respective blower module being configured so as to guide the cooling medium in each case onto the surface of the sheets to be cooled, the respective blower module comprising blower nozzles, the cooling medium being blown by these blower nozzles onto the surface of the respective sheet to be cooled, the respective blower module being configured so as to form, with a guide surface, a gap with respect to the surface of the relevant sheet to be cooled, the guide surface of the respective blower module being arranged at such a height above the surface of the relevant sheet to be cooled that the cross-section of an outer annular gap, through which a volume flow of the cooling medium exits the gap, is smaller than or almost equal to the sum cross-section across all opening surfaces of the blower nozzles in the guide surface.