A compound of Formula: or a pharmaceutically acceptable salt thereof, wherein R a, R b, and R c are independently selected from the group consisting of H, Me, halide, CF 3, C F 2, C H 2, and substituted or unsubstituted -(C 1 -C 5)alkylene-N-(R x)(R y); provided that at least one of R a, R b, and R c is -(C 1 -C 5)alkylene-N-(R x)(R y); R x and R y are independently selected from the group consisting of H and substituted or unsubstituted (C 1 -C 6)-alkyl; or R x and R y taken together with the N to which they are attached form an unsubstituted 4-6 membered ring or a substituted 4-6 membered ring, substituted with at least one halide, unsubstituted (C 1 -C 4) alkyl, or OMe; R 1 is substituted or unsubstituted (C 1 -C 6)-alkyl, substituted or unsubstituted (C 1 -C 4)-alkylene-(C 3 -C 6)-cycloalkyl, or substituted or unsubstituted (C 1 -C 4)-alkylene-(C 1 -C 4)-alkoxy; R 2 is R 3a and R 3b are independently selected from the group consisting of H, substituted or unsubstituted (C 1 -C 5)-alkyl, substituted or unsubstituted (C 3 -C 6)-cycloalkyl, substituted or unsubstituted 3-6 membered heterocycloalkyl, -OH, -CN, halide, CF 3, C F 2, C H 2, -(C 1 -C 4)-alkoxy, -OCF 3, and substituted or unsubstituted (C 1 -C 4)-alkylene-(C 1 -C 4)-alkoxy; provided that R 3a and R 3b are not both H; R 3c is H; R 3d is H; R 4 is H, or substituted or unsubstituted (C 1 -C 4)-alkyl; R 5a, and R 5e are independently selected from the group consisting of H, CN, halide, CF 3, C F 2, C H 2, substituted or unsubstituted (C 3 -C 6)-cycloalkyl, substituted or unsubstituted (C 1 -C 5)-alkyl, hydroxyl, and (C 1 -C 4)-alkoxy; and R 5b, R 5c, and R 5d are independently selected from the group consisting of H, CN, halide, CF 3, C F 2, C H 2, substituted or unsubstituted (C 1 -C 5)-alkyl, substituted or unsubstituted (C 3 -C 6)-cycloalkyl, substituted or unsubstituted 3-6 membered heterocycloalkyl, hydroxyl, and (C 1 -C 4)-alkoxy; wherein, unless otherwise specified, substituted means substituted with one or more substituents selected from alkyl, cycloalkyl, heterocyclylalkyl, halogen, OH, OMe, C F 2, C H 2, CF 3, C 2 CF 3, SF 5 CHFCH 2 amine, CH 2 amine, and CN. or a pharmaceutically acceptable salt thereof, wherein R a, R b, and R c are independently selected from the group consisting of H, Me, halide, CF 3, C F 2, C H 2, and substituted or unsubstituted -(C 1 -C 5)alkylene-N-(R x)(R y); provided that at least one of R a, R b, and R c is -(C 1 -C 5)alkylene-N-(R x)(R y); R x and R y are independently selected from the group consisting of H and substituted or unsubstituted (C 1 -C 6)-alkyl; or R x and R y taken together with the N to which they are attached form an unsubstituted 4-6 membered ring or a substituted 4-6 membered ring, substituted with at least one halide, unsubstituted (C 1 -C 4) alkyl, or OMe; R 1 is substituted or unsubstituted (C 1 -C 6)-alkyl, substituted or unsubstituted (C 1 -C 4)-alkylene-(C 3 -C 6)-cycloalkyl, or substituted or unsubstituted (C 1 -C 4)-alkylene-(C 1 -C 4)-alkoxy; R 2 is R 3a and R 3b are independently selected from the group consisting of H, substituted or unsubstituted (C 1 -C 5)-alkyl, substituted or unsubstituted (C 3 -C 6)-cycloalkyl, substituted or unsubstituted 3-6 membered heterocycloalkyl, -OH, -CN, halide, CF 3, C F 2, C H 2, -(C 1 -C 4)-alkoxy, -OCF 3, and substituted or unsubstituted (C 1 -C 4)-alkylene-(C 1 -C 4)-alkoxy; provided that R 3a and R 3b are not both H; R 3c is H; R 3d is H; R 4 is H, or substituted or unsubstituted (C 1 -C 4)-alkyl; R 5a, and R 5e are independently selected from the group consisting of H, CN, halide, CF 3, C F 2, C H 2, substituted or unsubstituted (C 3 -C 6)-cycloalkyl, substituted or unsubstituted (C 1 -C 5)-alkyl, hydroxyl, and (C 1 -C 4)-alkoxy; and R 5b, R 5c, and R 5d are independently selected from the group consisting of H, CN, halide, CF 3, C F 2, C H 2, substituted or unsubstituted (C 1 -C 5)-alkyl, substituted or unsubstituted (C 3 -C 6)-cycloalkyl, substituted or unsubstituted 3-6 membered heterocycloalkyl, hydroxyl, and (C 1 -C 4)-alkoxy; wherein, unless otherwise specified, substituted means substituted with one or more substituents selected from alkyl, cycloalkyl, heterocyclylalkyl, halogen, OH, OMe, C F 2, C H 2, CF 3, C 2 CF 3, SF 5 CHFCH 2 amine, CH 2 amine, and CN.