mhurhangee/ep-ind-claims huggingface dataset:
An apparatus for calculating an x-ray dose distribution within an object for a computed tomography examination, the apparatus comprising: - a model providing unit for providing a model of the object, wherein the model comprises voxels to which x-ray interaction properties are assigned, wherein an x-ray interaction property assigned to a voxel defines an influence of an x-ray traversing an object element of the object, which corresponds to the voxel, by the object element, - an x-ray parameters providing unit for providing x-ray parameters defining x-ray properties during the computed tomography examination, characterised by - a primary flux determination unit for determining a primary flux distribution within the object, which is caused by the computed tomography examination, based on the provided model and the provided x-ray parameters, wherein primary fluxes are determined, which are assigned to surfaces of the voxels, - a total flux determination unit for determining a total flux distribution within the object based on an initial total flux distribution, the provided model and the provided x-ray parameters by using a six-flux model algorithm, wherein the initial total flux distribution is defined by the determined primary flux distribution, and - a dose distribution determination unit for determining a total dose distribution within the object based on the determined total flux distribution. - a model providing unit for providing a model of the object, wherein the model comprises voxels to which x-ray interaction properties are assigned, wherein an x-ray interaction property assigned to a voxel defines an influence of an x-ray traversing an object element of the object, which corresponds to the voxel, by the object element, - an x-ray parameters providing unit for providing x-ray parameters defining x-ray properties during the computed tomography examination, - a primary flux determination unit for determining a primary flux distribution within the object, which is caused by the computed tomography examination, based on the provided model and the provided x-ray parameters, wherein primary fluxes are determined, which are assigned to surfaces of the voxels, - a total flux determination unit for determining a total flux distribution within the object based on an initial total flux distribution, the provided model and the provided x-ray parameters by using a six-flux model algorithm, wherein the initial total flux distribution is defined by the determined primary flux distribution, and - a dose distribution determination unit for determining a total dose distribution within the object based on the determined total flux distribution.
A non-transitory computer-readable storage device storing computer executable instructions that when executed by a computer control the computer to perform a method for predicting response to immunotherapy, the method comprising: accessing a radiological image of a region of tissue demonstrating cancerous pathology, where the radiological image is a pre-surgery three-dimensional computed tomography image of a region of tissue demonstrating non-small cell lung cancer (NSCLC), where the radiological image includes a plurality of voxels; specifying a region of interest in the image; defining a nodule surface based on the ROI, where the nodule surface defines a tumoral volume; extracting a set of discriminative tumoral features from the tumoral volume; defining a peritumoral volume using a morphologic dilation based on the tumoral volume; segmenting the peritumoral volume into a plurality of annular bands; extracting a set of discriminative peritumoral features from at least one of the plurality of annular bands; providing the set of discriminative tumoral features and the set of discriminative peritumoral features to a machine learning classifier; receiving, from the machine learning classifier, a classification of the region of tissue, where the classification is based on the set of discriminative tumoral features and the set of discriminative peritumoral features; and controlling a personalized cancer treatment system to generate a personalized treatment plan based, at least in part, on the classification, where the personalized treatment plan includes an immunotherapy recommendation, an immunotherapy dosage value, or an immunotherapy schedule. accessing a radiological image of a region of tissue demonstrating cancerous pathology, where the radiological image is a pre-surgery three-dimensional computed tomography image of a region of tissue demonstrating non-small cell lung cancer (NSCLC), where the radiological image includes a plurality of voxels; specifying a region of interest in the image; defining a nodule surface based on the ROI, where the nodule surface defines a tumoral volume; extracting a set of discriminative tumoral features from the tumoral volume; defining a peritumoral volume using a morphologic dilation based on the tumoral volume; segmenting the peritumoral volume into a plurality of annular bands; extracting a set of discriminative peritumoral features from at least one of the plurality of annular bands; providing the set of discriminative tumoral features and the set of discriminative peritumoral features to a machine learning classifier; receiving, from the machine learning classifier, a classification of the region of tissue, where the classification is based on the set of discriminative tumoral features and the set of discriminative peritumoral features; and controlling a personalized cancer treatment system to generate a personalized treatment plan based, at least in part, on the classification, where the personalized treatment plan includes an immunotherapy recommendation, an immunotherapy dosage value, or an immunotherapy schedule.
Method for operating a strip casting installation (101...104) comprising the steps: - moving an endless belt in at least one main direction of movement, - applying a liquid or pasty material to the aforementioned endless belt, - lifting off the at least partially solidified material from the endless belt and - activating a cleaning device (8, 81...83) fixedly connected to the strip casting installation (101...104) at least at certain times, characterised in that a polishing device fixedly connected to the strip casting installation (101...104) and having at least one rotating polishing plate and/or vibrating polisher and/or eccentric polisher is also activated at least at certain times. - moving an endless belt in at least one main direction of movement, - applying a liquid or pasty material to the aforementioned endless belt, - lifting off the at least partially solidified material from the endless belt and - activating a cleaning device (8, 81...83) fixedly connected to the strip casting installation (101...104) at least at certain times,
A method of making a wafer level chip scale packaging (WLCSP) structure (200, 300), characterized in that the method comprises following steps in sequence: providing a wafer, comprising a plurality of bottom chips; bonding the wafer with a carrier; mounting a plurality of stacked chip sets on the plurality of bottom chips; dicing the wafer to separate the plurality of bottom chips from each other and from a plurality of peripheral portions of the wafer; removing the plurality of peripheral portions; and molding the plurality of bottom chips with a mold to form the packaging structure. providing a wafer, comprising a plurality of bottom chips; bonding the wafer with a carrier; mounting a plurality of stacked chip sets on the plurality of bottom chips; dicing the wafer to separate the plurality of bottom chips from each other and from a plurality of peripheral portions of the wafer; removing the plurality of peripheral portions; and molding the plurality of bottom chips with a mold to form the packaging structure.
A position measurement system for measuring positional information of a movable body movable within a predetermined planar surface, the system comprising: a first grating placed on a predetermined plane parallel to the predetermined planar surface of one of the movable body and the outside of the movable body, the first grating including a grating (39Y 1, 39Y 2) whose periodic direction is in a predetermined direction; and an encoder that has at least one head arranged at the other of the movable body and the outside of the movable body, and which is arranged to measure positional information of the movable body in the predetermined direction, based on an output of a head that faces the first grating, characterized in that the system comprises a calibration area that is arranged at a position different from the first grating in the predetermined direction on the predetermined plane, wherein in the calibration area, a second grating is placed, the second grating including a grating (39Y 3, 39Y 4) whose periodic direction is in the predetermined direction and the second grating having a size in the periodic direction smaller than the first grating. a first grating placed on a predetermined plane parallel to the predetermined planar surface of one of the movable body and the outside of the movable body, the first grating including a grating (39Y 1, 39Y 2) whose periodic direction is in a predetermined direction; and an encoder that has at least one head arranged at the other of the movable body and the outside of the movable body, and which is arranged to measure positional information of the movable body in the predetermined direction, based on an output of a head that faces the first grating, characterized in that the system comprises a calibration area that is arranged at a position different from the first grating in the predetermined direction on the predetermined plane, wherein in the calibration area, a second grating is placed, the second grating including a grating (39Y 3, 39Y 4) whose periodic direction is in the predetermined direction and the second grating having a size in the periodic direction smaller than the first grating.
A pool cleaning robot that comprises a fluid inlet, a filter; and a holding mechanism, wherein the holding mechanism is configured to hold the filter; wherein the pool cleaning robot is characterized by comprising a winding mechanism, wherein the winding mechanism is configured to perform a winding of the filter thereby removing a filter portion that was positioned in a filtering position and placing another filter portion in the filtering position; wherein the filter portion, when positioned in the filtering position, is configured to filter fluid that enters through the fluid inlet.
A power electronic transformer, comprising at least N low-voltage circuit branches, wherein each low-voltage circuit branch is respectively provided with a voltage transformation unit (T1, T2...Tn), all the voltage transformation units (T1, T2...Tn) are disposed adjacently, and N is a natural number greater than 3, characterized in that an (M-1)th voltage transformation unit (Tm-1) and an (M+1)th voltage transformation unit (Tm+1) on two sides of any one Mth voltage transformation unit (Tm) amongst the voltage transformation units have opposite magnetic flux directions, wherein M is an integer greater than 1 and less than N.
A compound having formula I, or a pharmaceutically acceptable salt thereof, wherein; each R is independently H or -C 1 -C 3 alkyl; R 1 is unsubstituted cyclopropyl or cyclobutyl; B is A 1, wherein A 1 has the structure of formula II: wherein Y 1 is -CH- or -N- and Y 2 is -N-; A is A 2 wherein A 2 is 3,5-bis-trifluoromethylphenyl; R a1 is 3-fluoroazetidinyl, 4-morpholinyl, CF 3, -N(CH 3) 2, -N(CH 3)(SO 2 CH 3), or CH 3 S-, A 3 is wherein Y 3 is -CH- or -N-; X is 3-cyclobutyl-D 1, 3-cyclobutyl-CH 2 OH, 2-methyl-4-phenyl-D 1, 2-methyl-4-phenyl-CH 2 OH, -CH 2 CH 2 D 1, -CH 2 OH, or isopropyl, wherein D 1 is -CO 2 R 8; R 8 is H or -CH 3; R b is -OCH 3 or halogen; d is 0; and e is an integer from 0-3. each R is independently H or -C 1 -C 3 alkyl; R 1 is unsubstituted cyclopropyl or cyclobutyl; B is A 1, wherein A 1 has the structure of formula II: wherein Y 1 is -CH- or -N- and Y 2 is -N-; A is A 2 wherein A 2 is 3,5-bis-trifluoromethylphenyl; R a1 is 3-fluoroazetidinyl, 4-morpholinyl, CF 3, -N(CH 3) 2, -N(CH 3)(SO 2 CH 3), or CH 3 S-, A 3 is wherein Y 3 is -CH- or -N-; X is 3-cyclobutyl-D 1, 3-cyclobutyl-CH 2 OH, 2-methyl-4-phenyl-D 1, 2-methyl-4-phenyl-CH 2 OH, -CH 2 CH 2 D 1, -CH 2 OH, or isopropyl, wherein D 1 is -CO 2 R 8; R 8 is H or -CH 3; R b is -OCH 3 or halogen; d is 0; and e is an integer from 0-3. wherein Y 1 is -CH- or -N- and Y 2 is -N-; A is A 2 wherein A 2 is 3,5-bis-trifluoromethylphenyl; R a1 is 3-fluoroazetidinyl, 4-morpholinyl, CF 3, -N(CH 3) 2, -N(CH 3)(SO 2 CH 3), or CH 3 S-, A 3 is wherein Y 3 is -CH- or -N-; X is 3-cyclobutyl-D 1, 3-cyclobutyl-CH 2 OH, 2-methyl-4-phenyl-D 1, 2-methyl-4-phenyl-CH 2 OH, -CH 2 CH 2 D 1, -CH 2 OH, or isopropyl, wherein D 1 is -CO 2 R 8; R 8 is H or -CH 3; R b is -OCH 3 or halogen; d is 0; and e is an integer from 0-3. wherein Y 3 is -CH- or -N-; X is 3-cyclobutyl-D 1, 3-cyclobutyl-CH 2 OH, 2-methyl-4-phenyl-D 1, 2-methyl-4-phenyl-CH 2 OH, -CH 2 CH 2 D 1, -CH 2 OH, or isopropyl, wherein D 1 is -CO 2 R 8; R 8 is H or -CH 3; R b is -OCH 3 or halogen; d is 0; and e is an integer from 0-3.
System for acquiring data from the surface of bones and joints for surgical planning and manufacturing of patient-specific templates and patient specific instruments using an apparatus comprised of three units: a data collection unit, a computerized unit and a desktop 3D printer, which are functionally, physically and electrically connected to each other in a compact, portable fashion and suitable for hospital-based or clinic-based service, wherein: - the data-collection unit comprises four components: electro-magnetic device, diagnostic ultrasound machine, laser scanner and a receiver for acquisition of external data, which are physically and electrically connected and function as one unit that integrates the data from multiple sources and has sensor fusion ability; - the apparatus further comprises a compatible diagnostic 3D ultrasound machine and its software with musculoskeletal probe, said US machine being designed to complement the other three components in the data-collection unit in order to formulate a complete dataset for the area of interest of bones and joints - the data-collection unit comprises four components: electro-magnetic device, diagnostic ultrasound machine, laser scanner and a receiver for acquisition of external data, which are physically and electrically connected and function as one unit that integrates the data from multiple sources and has sensor fusion ability; - the apparatus further comprises a compatible diagnostic 3D ultrasound machine and its software with musculoskeletal probe, said US machine being designed to complement the other three components in the data-collection unit in order to formulate a complete dataset for the area of interest of bones and joints
Sectional roller gate with its panel made up of horizontal, parallel and articulated lath sections rolled up in layers on a rotary shaft, wherein the side edges of the panel are seated in a sliding manner in guide rails of a profile close to the C-shape which enclose the panel at both sides, characterised in that it has at least one elastic smoke-tight jacket which adheres to the front surface (7, 7') of its panel, and the side edges of which are within the vertical guide rails together with the side edges of the lath sections of the panel, and at both guide rails, on their outer sides elastic sealing slats are vertically mounted and adhere at both sides to the sectional panel, wherein at the gate's lintel edges the elastic sealing slat is horizontally mounted which adheres to the sectional panel at the inner side, and on the lower end lath section of its panel sealing slats are horizontally mounted which, when the gate is closed, adhere to its base at both sides of the panel.
An electrical connector, comprising: a yoke comprised of an outer housing and a central conductor within the outer housing, wherein the yoke can be connected to at least one cable; a sacrificial appendage releasably retained within the yoke and in conductive contact with the yoke central conductor, the sacrificial appendage configured to be cut through in order to confirm that the electrical connector is de-energized; wherein after cutting the sacrificial appendage, the sacrificial appendage is removable from the yoke, characterized in that: after removing the sacrificial appendage, a releasably retained ground rod is mounted to the yoke in place of the sacrificial appendage and in conductive contact with the central conductor, wherein the ground rod is configured to be connectable to system ground to ground the electrical connector to allow at least one cable or circuit connectable thereto to be serviced; wherein after service is completed, the ground rod is removed from the yoke and replaced with a new, intact sacrificial appendage which is releasably retained within the yoke and which is mechanically and conductively connected to the central conductor so that the electrical connector may be re-energized. a yoke comprised of an outer housing and a central conductor within the outer housing, wherein the yoke can be connected to at least one cable; a sacrificial appendage releasably retained within the yoke and in conductive contact with the yoke central conductor, the sacrificial appendage configured to be cut through in order to confirm that the electrical connector is de-energized; wherein after cutting the sacrificial appendage, the sacrificial appendage is removable from the yoke, characterized in that: after removing the sacrificial appendage, a releasably retained ground rod is mounted to the yoke in place of the sacrificial appendage and in conductive contact with the central conductor, wherein the ground rod is configured to be connectable to system ground to ground the electrical connector to allow at least one cable or circuit connectable thereto to be serviced; wherein after service is completed, the ground rod is removed from the yoke and replaced with a new, intact sacrificial appendage which is releasably retained within the yoke and which is mechanically and conductively connected to the central conductor so that the electrical connector may be re-energized. after removing the sacrificial appendage, a releasably retained ground rod is mounted to the yoke in place of the sacrificial appendage and in conductive contact with the central conductor, wherein the ground rod is configured to be connectable to system ground to ground the electrical connector to allow at least one cable or circuit connectable thereto to be serviced; wherein after service is completed, the ground rod is removed from the yoke and replaced with a new, intact sacrificial appendage which is releasably retained within the yoke and which is mechanically and conductively connected to the central conductor so that the electrical connector may be re-energized.
A container suitable for collecting a cell-containing sample, preferably a blood, plasma or serum sample, comprising - a stabilizing composition suitable for stabilizing an extracellular nucleic acid population comprised in the cell-containing sample, wherein said stabilizing composition comprises a caspase inhibitor, and - at least one compound according to formula 1, wherein R1 is a hydrogen residue or an alkyl residue, preferably a C1-C5 alkyl residue, more preferred a methyl residue, R2 and R3 are identical or different hydrocarbon residues with a length of the carbon chain of 1 - 20 atoms arranged in a linear or branched manner, and R4 is an oxygen, sulphur or selenium residue. - a stabilizing composition suitable for stabilizing an extracellular nucleic acid population comprised in the cell-containing sample, wherein said stabilizing composition comprises a caspase inhibitor, and - at least one compound according to formula 1, wherein R1 is a hydrogen residue or an alkyl residue, preferably a C1-C5 alkyl residue, more preferred a methyl residue, R2 and R3 are identical or different hydrocarbon residues with a length of the carbon chain of 1 - 20 atoms arranged in a linear or branched manner, and R4 is an oxygen, sulphur or selenium residue.
A chloroprene rubber composition, prepared by carrying out emulsion polymerization of a total 100 parts by mass of monomers at least containing chloroprene in the presence of 0.5 to 7.0 parts by mass of a rosin acid salt as emulsifier and terminating the emulsion polymerization by addition of a polymerization inhibitor and a phosphorus- or phenol-based compound as antioxidant, wherein the phenol- and phosphorus-based compounds are used in combination as the antioxidants added to terminate the emulsion polymerization.
A thermometer capable of automatically switching operational mode, comprising: a control unit configured to determine that the thermometer is to enter or leave from a first mode or a second mode; a power supply unit configured to provide power required by the thermometer; and a power circuit comprising the power supply unit and electrically connected to the control unit for power supply, and wherein the power circuit comprises a detection unit electrically connected to the power supply unit and the control unit, and the detection unit is configured to detect when the thermometer is shaken from a standing state, and enable the control unit to determine that the thermometer is to leave from the first mode and enter the second mode; wherein a change in voltage level on a pin of the control unit is associated with a shaking state of the thermometer detected by the detection unit; the thermometer being characterised in that the power circuit comprises a transistor having a collector connected to an operation voltage terminal and the pin, an emitter connected to a ground terminal of the control unit, and a base connected to the operation voltage through a first resistor and to ground through a second resistor, and a capacitor is connected between the base and the emitter of the transistor, wherein the detection unit and a third resistor are connected in series between the base and the emitter of the transistor, and the first resistor, the second resistor, the third resistor, and the capacitor are configured to adjust a sensitivity of the detection unit detecting the shaking state. a control unit configured to determine that the thermometer is to enter or leave from a first mode or a second mode; a power supply unit configured to provide power required by the thermometer; and a power circuit comprising the power supply unit and electrically connected to the control unit for power supply, and wherein the power circuit comprises a detection unit electrically connected to the power supply unit and the control unit, and the detection unit is configured to detect when the thermometer is shaken from a standing state, and enable the control unit to determine that the thermometer is to leave from the first mode and enter the second mode; wherein a change in voltage level on a pin of the control unit is associated with a shaking state of the thermometer detected by the detection unit; the thermometer being characterised in that the power circuit comprises a transistor having a collector connected to an operation voltage terminal and the pin, an emitter connected to a ground terminal of the control unit, and a base connected to the operation voltage through a first resistor and to ground through a second resistor, and a capacitor is connected between the base and the emitter of the transistor, wherein the detection unit and a third resistor are connected in series between the base and the emitter of the transistor, and the first resistor, the second resistor, the third resistor, and the capacitor are configured to adjust a sensitivity of the detection unit detecting the shaking state.