A computer-implemented method of analyzing a dental treatment plan, the method comprising: performing a scan of dentition; generating a digital dental model from the scan of the dentition, the digital dental model representing a position and an orientation of each tooth in upper and lower dental arches of the dentition with respect to each other tooth; performing a dentition motion assessment by capturing motion data, the motion data representing a movement of upper and lower dental arches of the dentition relative to each other; determining a pre-treatment interference boundary based on the scan and the dentition motion assessment, wherein the pre-treatment interference boundary is a boundary of function between opposing teeth of upper and lower dental arches prior to implementing the dental treatment plan, and is defined by an interface or interaction between the opposing teeth; determining a dental treatment plan with a dentition adjustment based on the scan, the digital dental model, the pre-treatment interference surface boundary, and the dentition motion assessment to avoid introducing interferences between the opposing teeth; predicting a motion adjustment based on the dentition adjustment; and modifying the dental treatment plan based on the predicted motion adjustment; and wherein predicting the motion adjustment based on the dentition adjustment comprises: determining a location of a screw axis about which a lower jaw rotates and translates along; determining one or more other jaw-related parameters; and simulating a range of motion of the lower jaw within a digital dental model that includes the dentition adjustment, the range of motion based on the location of the screw axis and the one or more other jaw-related parameters. performing a scan of dentition; generating a digital dental model from the scan of the dentition, the digital dental model representing a position and an orientation of each tooth in upper and lower dental arches of the dentition with respect to each other tooth; performing a dentition motion assessment by capturing motion data, the motion data representing a movement of upper and lower dental arches of the dentition relative to each other; determining a pre-treatment interference boundary based on the scan and the dentition motion assessment, wherein the pre-treatment interference boundary is a boundary of function between opposing teeth of upper and lower dental arches prior to implementing the dental treatment plan, and is defined by an interface or interaction between the opposing teeth; determining a dental treatment plan with a dentition adjustment based on the scan, the digital dental model, the pre-treatment interference surface boundary, and the dentition motion assessment to avoid introducing interferences between the opposing teeth; predicting a motion adjustment based on the dentition adjustment; and modifying the dental treatment plan based on the predicted motion adjustment; and wherein predicting the motion adjustment based on the dentition adjustment comprises: determining a location of a screw axis about which a lower jaw rotates and translates along; determining one or more other jaw-related parameters; and simulating a range of motion of the lower jaw within a digital dental model that includes the dentition adjustment, the range of motion based on the location of the screw axis and the one or more other jaw-related parameters. determining a location of a screw axis about which a lower jaw rotates and translates along; determining one or more other jaw-related parameters; and simulating a range of motion of the lower jaw within a digital dental model that includes the dentition adjustment, the range of motion based on the location of the screw axis and the one or more other jaw-related parameters.