mhurhangee/ep-ind-claims huggingface dataset:
Process for preparing the dimaleate of 4-[(3-chloro-4-fluorophenyl)amino]-6 {[4-(N,N-dimethylamino)-1-oxo-2-buten-1-yl]amino}-7-( -tetrahydrofuran-3-yloxy)-quinazoline, comprising steps a and b a) reacting a compound of general formula wherein X denotes a nitrogen atom and R a denotes the 3-chloro-4-fluorophenyl group, in suitable solvents after corresponding activation with di-(C 1-4 -alkyl)-phosphonoacetic acid and b) reacting the resulting compound of general formula wherein X denotes a nitrogen atom, R a denotes the 3-chloro-4-fluorophenyl group and R 1 denotes a straight-chain or branched C 1-4 -alkyl group, with the aldehyde of formula wherein R 3 and R 4 in each case represent a methyl group, or a corresponding aldehyde equivalent, using suitable organic or inorganic bases, as well as the following step c): c) converting the resulting 4-[(3-chloro-4-fluorophenyl)amino]-6-{[4-(N,N-dimethylamino)-1-oxo-2-buten-1-yl]amino}-7-( -tetrahydrofuran-3-yloxy)-quinazoline into the dimaleate by reacting with maleic acid in a suitable solvent, with heating. a) reacting a compound of general formula wherein X denotes a nitrogen atom and R a denotes the 3-chloro-4-fluorophenyl group, in suitable solvents after corresponding activation with di-(C 1-4 -alkyl)-phosphonoacetic acid and b) reacting the resulting compound of general formula wherein X denotes a nitrogen atom, R a denotes the 3-chloro-4-fluorophenyl group and R 1 denotes a straight-chain or branched C 1-4 -alkyl group, with the aldehyde of formula wherein R 3 and R 4 in each case represent a methyl group, or a corresponding aldehyde equivalent, using suitable organic or inorganic bases, as well as the following step c): c) converting the resulting 4-[(3-chloro-4-fluorophenyl)amino]-6-{[4-(N,N-dimethylamino)-1-oxo-2-buten-1-yl]amino}-7-( -tetrahydrofuran-3-yloxy)-quinazoline into the dimaleate by reacting with maleic acid in a suitable solvent, with heating.
A method for estimating a frequency offset of a base station, comprising: obtaining (S400, S600) a first symbol from which a cyclic prefix, CP, symbol of a received OFDM symbol is removed; obtaining (S410, S610) a second symbol from which data having a length corresponding to the CP symbol is removed at an end opposite to an end in which the CP symbol of the received OFDM symbol; and estimating (S420-S470, S620-S680) the frequency offset based on a correlation between the first symbol and the second symbol in frequency domain. obtaining (S400, S600) a first symbol from which a cyclic prefix, CP, symbol of a received OFDM symbol is removed; obtaining (S410, S610) a second symbol from which data having a length corresponding to the CP symbol is removed at an end opposite to an end in which the CP symbol of the received OFDM symbol; and estimating (S420-S470, S620-S680) the frequency offset based on a correlation between the first symbol and the second symbol in frequency domain.
A compound of formula for use in therapy, wherein formula is: or a pharmaceutically acceptable salt thereof, wherein: R 1 is hydrogen or halogen; R 2 is hydrogen or chlorine; R 3 is hydrogen or chlorine; and R 4 is R 1 is hydrogen or halogen; R 2 is hydrogen or chlorine; R 3 is hydrogen or chlorine; and R 4 is
A removable electrode module for engagement with an electrolysis chamber, the removable electrode module comprising, a first electrode, a second electrode, and a suspension structure comprising a suspension rod coupled, preferably at one end of the rod, to the first electrode, in which the second electrode is suspended by, or supported by, the suspension structure and in which the suspension structure comprises at least one electrically-insulating spacer element for retaining the second electrode in spatial separation from the first electrode.
A process of configuring a standalone self-supplied numeric controlled relay for providing phase and earth over current protection to electrical systems by accurate current measurement, comprising the steps of: - preparing a power supply by rectifying the current from at least one current transformer by means of a full-bridge rectifier; - storing the prepared power supply into a bus capacitor, all the three phases of the rectifier being connected in parallel with respect to the capacitor; - reducing the bus capacitor voltage from 24V to +12V at a first stage by adapting a first linear regulator, the +12V being supplied to an analog sensing circuit, a trip coil energy reservoir, and a FLAG operation energy storage; - reducing the regulated voltage from +12V to +3.3V at a second stage by adapting a second linear regulator, the +3.3V being supplied to a microcontroller as reference; and - providing a switch and a shunt in series with a current path of the current transformer secondary to convert current signal to voltage signal; - providing a potential divider for dividing the voltage signal and providing a spike suppressor across the analog sensing circuit and the analog sensing circuit providing a conditioned current, being supplied to the microcontroller, including the voltage signal, the microcontroller monitoring line current and line current frequency based on the conditioned current - wherein the switch is turned "ON" to have the shunt appear across the current transformer secondary for current measurement. - preparing a power supply by rectifying the current from at least one current transformer by means of a full-bridge rectifier; - storing the prepared power supply into a bus capacitor, all the three phases of the rectifier being connected in parallel with respect to the capacitor; - reducing the bus capacitor voltage from 24V to +12V at a first stage by adapting a first linear regulator, the +12V being supplied to an analog sensing circuit, a trip coil energy reservoir, and a FLAG operation energy storage; - reducing the regulated voltage from +12V to +3.3V at a second stage by adapting a second linear regulator, the +3.3V being supplied to a microcontroller as reference; and - providing a switch and a shunt in series with a current path of the current transformer secondary to convert current signal to voltage signal; - providing a potential divider for dividing the voltage signal and providing a spike suppressor across the analog sensing circuit and the analog sensing circuit providing a conditioned current, being supplied to the microcontroller, including the voltage signal, the microcontroller monitoring line current and line current frequency based on the conditioned current - wherein the switch is turned "ON" to have the shunt appear across the current transformer secondary for current measurement.
A method for recovering lithium from lithium ion battery scrap which has been subjected to a calcination step performed in a temperature range of from 550 °C to 650 °C, the method comprising: a lithium dissolution step of bringing the lithium ion battery scrap into contact with water and dissolving lithium contained in the lithium ion battery scrap in the water to obtain a lithium-dissolved solution; a lithium concentration step of solvent-extracting lithium ions contained in the lithium-dissolved solution and stripping them to concentrate the lithium ions to obtain a lithium concentrate; a carbonation step of carbonating the lithium ions in the lithium concentrate to obtain lithium carbonate; and wherein a pH of the lithium-dissolved solution is from 7 to 10 and an aluminum concentration of the lithium-dissolved solution is from 0 mg/L to 500 mg/L. a lithium dissolution step of bringing the lithium ion battery scrap into contact with water and dissolving lithium contained in the lithium ion battery scrap in the water to obtain a lithium-dissolved solution; a lithium concentration step of solvent-extracting lithium ions contained in the lithium-dissolved solution and stripping them to concentrate the lithium ions to obtain a lithium concentrate; a carbonation step of carbonating the lithium ions in the lithium concentrate to obtain lithium carbonate; and wherein a pH of the lithium-dissolved solution is from 7 to 10 and an aluminum concentration of the lithium-dissolved solution is from 0 mg/L to 500 mg/L.
A ball joint comprising a ring-shaped outer housing which consists of at least one sheet metal sleeve, a ring-shaped inner housing which is firmly received in the outer housing in the axial direction and which consists of at least one metal sleeve, a bearing shell received in the inner housing, and a ball stud which is received in the bearing shell, characterized in that two support rings are provided between the inner housing and the outer housing, which are welded to the inner housing and the outer housing, a free space being provided between the inner wall of the outer housing and the outer wall of the inner housing.
A vapour deposition method for preparing an amorphous lithium borosilicate or doped lithium borosilicate compound, the method comprising: providing a vapour source of each component element of the compound, wherein the vapour sources comprise at least a source of lithium, a source of oxygen, a source of boron, and a source of silicon, and, optionally, a source of at least one dopant element; delivering a flow of said lithium, said oxygen, said boron and said silicon, and, optionally, said dopant element; and co-depositing the component elements from the vapour sources onto a substrate wherein the component elements react on the substrate to form the amorphous compound; wherein the amorphous lithium borosilicate or doped lithium borosilicate compound has a lithium content in the range 40-65 atomic%, based on the combined atomic percentages of lithium, boron and silicon. providing a vapour source of each component element of the compound, wherein the vapour sources comprise at least a source of lithium, a source of oxygen, a source of boron, and a source of silicon, and, optionally, a source of at least one dopant element; delivering a flow of said lithium, said oxygen, said boron and said silicon, and, optionally, said dopant element; and co-depositing the component elements from the vapour sources onto a substrate wherein the component elements react on the substrate to form the amorphous compound; wherein the amorphous lithium borosilicate or doped lithium borosilicate compound has a lithium content in the range 40-65 atomic%, based on the combined atomic percentages of lithium, boron and silicon.
A process for producing Co, Al alloyed NdFeB nanoparticles, by a microwave assisted combustion process, followed by a reduction diffusion process, the process comprising the steps of: preparing a first solution of boric acid dissolved in 4 N Nitric Acid (HNO 3); dissolving iron nitrate nonahydrate, neodymium nitrate nonahydrate, cobalt nitrate hexahydrate, aluminium nitrate, and the first solution in deionized water to form a second solution; adding glycine to the second solution in a molar ratio of 1:1 to form a third solution; subjecting the third solution to microwave radiation, thereby forming an first powder of NdFeCoAlB oxides; mixing the first powder with calcium hydride in a mass ratio of 1:1.1 (NdFeCoAlB oxides:CaH 2) to form a second powder, compacted into a powder block; annealing the second powder in a vacuum furnace; washing the annealed second powder with a solution of ethylenediaminetetraacetic acid; and vacuum drying the second powder. preparing a first solution of boric acid dissolved in 4 N Nitric Acid (HNO 3); dissolving iron nitrate nonahydrate, neodymium nitrate nonahydrate, cobalt nitrate hexahydrate, aluminium nitrate, and the first solution in deionized water to form a second solution; adding glycine to the second solution in a molar ratio of 1:1 to form a third solution; subjecting the third solution to microwave radiation, thereby forming an first powder of NdFeCoAlB oxides; mixing the first powder with calcium hydride in a mass ratio of 1:1.1 (NdFeCoAlB oxides:CaH 2) to form a second powder, compacted into a powder block; annealing the second powder in a vacuum furnace; washing the annealed second powder with a solution of ethylenediaminetetraacetic acid; and vacuum drying the second powder.
Motor with constant moment of force for a timepiece, comprising at least one energy accumulator element (102, 102', 102", 14) able to accumulate and give back the energy which can be used for driving a mechanical mechanism between a loaded state (102") and an unloaded state, and at least one controller element (104, 104', 104", 18, 44, 52) able to control the accumulator element (102, 102', 102") owing to a movement of relative displacement between this controller element (104, 104', 104") and the accumulator element (102, 102', 102"), such that the moment of force created by the accumulator element (102, 102', 102") remains substantially constant between the loaded state (102") and the unloaded state, the controller element (104, 104', 104", 18, 44, 52) being designed to displace itself along the accumulator element (102, 102', 102"), characterized in that the accumulator element is a blade.
Dust extraction unit for a vacuum cleaner, wherein the dust extraction unit has a wall which at least partly surrounds the dust extraction unit and the wall of the dust extraction unit has an intermediate coupling with a mating drive coupling accessible from outside the dust extraction unit and a mating take-off coupling accessible from inside the dust extraction unit, wherein the intermediate coupling has a surrounding edge which is supported in an annular groove of the wall of the dust extraction unit, characterised in that the edge encloses the drive coupling and take-off coupling of the intermediate coupling in a radial direction in a disc shape.
A compound for use in a method of treating head and neck squamous cell carcinoma (HNSCC) in a patient, wherein the patient has a H-Ras mutation, wherein the H-Ras mutation results in the activation of the H-Ras protein, wherein the compound is tipifarnib, and wherein said HNSCC is metastatic, recurrent or refractory.
A training sequence comprising N preambles (900, 910, 950, 960, 970, 1000, 1100) configured respectively for transmission from at least N antennas of a wireless communication system conforming to an 802.11 standard, each of the N preambles (900, 910, 950, 960, 970, 1000,1100) comprising: a short training sequence field (920, 1005); a long training sequence field (930, 1015, 1030); and a signal field (935, 1035); characterized in that the signal field (935, 1035) and at least one of the short training sequence field (920, 1005) and the long training sequence field (930, 1015, 1030) of at least one of the N preambles have a cyclic shift with respect to the respective short training sequence field (920, 1005), long training sequence field (930, 1015, 1030) and signal field (935, 1035) of another one of the N preambles, and wherein each preamble (1000, 1100) comprises a first part (1050, 1110) defined by the 802.11 a standard, and a second part (1060, 1120) comprising at least one field that is distinguishable from the preamble defined by the 802.11 a standard. a short training sequence field (920, 1005); a long training sequence field (930, 1015, 1030); and a signal field (935, 1035);
Device for use at the location of a customer of a broadband network system provided with one or more user ports for connecting appliances of the customer to optical fibres and in which signals received from an incoming optical fibre are converted using a transceiver into electrical signals that, after additional processing to make them suitable for the appliances, are offered to the user ports for supply to the appliances concerned, the device comprising a first module that comprises the transceiver that has on one side been connected to the incoming optical fibre and that comprises a second module with the user ports on the user-accessible outside, within which means for carrying out the additional processing reside, characterized in that the second module has been detachably attached to the first mo dule using a co-operating attachment means present at the modules (11,12) in which two opposite sides of the modules (11,12) are provided with mutually corresponding connector parts forming together a connection by means of which the signals coming from the transceiver are during use led from the first module to the second module.
A coordinate measuring machine comprising: a motor; a measuring member; a counterweight; a pulley and cable system (32, 31) coupling the measuring member with the counterweight; a guide track, the counterweight being movably secured to the guide track, the guide track substantially limiting counterweight movement to one dimension; and a pulley and belt system (22, 23, 24) coupling the counterweight and the motor, wherein the pulley and belt system (22, 23, 24) is a mechanical low-pass filter adapted to decouple dynamic and static noise between the motor and the rest of the coordinate measuring machine system, and wherein the pulley and cable system (32, 31) is configured as a high-efficiency isolation transformer by which vibration and dynamic noise introduced by the motor, external stimuli, and other parasitic motions may be filtered out. a motor; a measuring member; a counterweight; a pulley and cable system (32, 31) coupling the measuring member with the counterweight; a guide track, the counterweight being movably secured to the guide track, the guide track substantially limiting counterweight movement to one dimension; and a pulley and belt system (22, 23, 24) coupling the counterweight and the motor, wherein the pulley and belt system (22, 23, 24) is a mechanical low-pass filter adapted to decouple dynamic and static noise between the motor and the rest of the coordinate measuring machine system, and wherein the pulley and cable system (32, 31) is configured as a high-efficiency isolation transformer by which vibration and dynamic noise introduced by the motor, external stimuli, and other parasitic motions may be filtered out.
A method for wireless communication, comprising: determining, at a user equipment, UE, available transmit power for data transmission on multiple carriers; distributing, at the UE, the available transmit power to the multiple carriers to obtain allocated transmit power information for each of the multiple carriers; and sending, from the UE, at least one resource request comprising the allocated transmit power information for each of the multiple carriers; and receiving, at the UE, at least one resource grant comprising information indicative of granted transmit power for each of at least one carrier among the multiple carriers. wherein the distributing the available transmit power comprises: selecting a carrier among the multiple carriers to allocate transmit power, allocating the selected carrier with a lower of all available transmit power or maximum allowed transmit power for the selected carrier, and updating the available transmit power to account for the transmit power allocated to the selected carrier. wherein the distributing the available transmit power further comprises determining whether to redistribute the allocated transmit power for the selected carrier to a next worse carrier. determining, at a user equipment, UE, available transmit power for data transmission on multiple carriers; distributing, at the UE, the available transmit power to the multiple carriers to obtain allocated transmit power information for each of the multiple carriers; and sending, from the UE, at least one resource request comprising the allocated transmit power information for each of the multiple carriers; and receiving, at the UE, at least one resource grant comprising information indicative of granted transmit power for each of at least one carrier among the multiple carriers. wherein the distributing the available transmit power comprises: selecting a carrier among the multiple carriers to allocate transmit power, allocating the selected carrier with a lower of all available transmit power or maximum allowed transmit power for the selected carrier, and updating the available transmit power to account for the transmit power allocated to the selected carrier. wherein the distributing the available transmit power further comprises determining whether to redistribute the allocated transmit power for the selected carrier to a next worse carrier. selecting a carrier among the multiple carriers to allocate transmit power, allocating the selected carrier with a lower of all available transmit power or maximum allowed transmit power for the selected carrier, and updating the available transmit power to account for the transmit power allocated to the selected carrier. wherein the distributing the available transmit power further comprises determining whether to redistribute the allocated transmit power for the selected carrier to a next worse carrier.
A turbine nozzle comprising: an endwall (103, 105); a vane coupled to the endwall (103,105), the vane comprising: a leading edge and a trailing edge interconnected by a pressure sidewall and a suction sidewall; and an end portion (138, 140); a slip joint between the end portion (138, 140) and the endwall (103, 105); and a plurality of endwall cooling holes defined through the endwall (103, 105) along the pressure sidewall and in proximity to the leading edge and disposed adjacent the slip joint, characterised in that a plurality of airfoil quenching holes defined through the pressure sidewall in the end portion (138, 140) of the vane, the plurality of airfoil quenching holes cooperating with said plurality of endwall cooling holes, the plurality of airfoil quenching holes disposed adjacent the slip joint and the plurality of airfoil quenching holes each have an outlet opening onto an outer surface of the end portion (138, 140) of the vane, wherein the plurality of airfoil quenching holes is selectively located through the pressure sidewall in the end portion (138, 140) and the plurality of endwall cooling holes is selectively located along the pressure sidewall and in proximity to the leading edge to mix with and follow a combustion gas flow path through the slip joint. an endwall (103, 105); a vane coupled to the endwall (103,105), the vane comprising: a leading edge and a trailing edge interconnected by a pressure sidewall and a suction sidewall; and an end portion (138, 140); a leading edge and a trailing edge interconnected by a pressure sidewall and a suction sidewall; and an end portion (138, 140); a slip joint between the end portion (138, 140) and the endwall (103, 105); and a plurality of endwall cooling holes defined through the endwall (103, 105) along the pressure sidewall and in proximity to the leading edge and disposed adjacent the slip joint, characterised in that a plurality of airfoil quenching holes defined through the pressure sidewall in the end portion (138, 140) of the vane, the plurality of airfoil quenching holes cooperating with said plurality of endwall cooling holes, the plurality of airfoil quenching holes disposed adjacent the slip joint and the plurality of airfoil quenching holes each have an outlet opening onto an outer surface of the end portion (138, 140) of the vane, wherein the plurality of airfoil quenching holes is selectively located through the pressure sidewall in the end portion (138, 140) and the plurality of endwall cooling holes is selectively located along the pressure sidewall and in proximity to the leading edge to mix with and follow a combustion gas flow path through the slip joint.