A penetrating connector (3600, 3700, 3800) configured to be positioned along a fluid line between a medical device and a source of body fluid to allow fluid flow while reducing leaks, the connector comprising first and second openings at opposite ends of the connector, the openings configured to: allow fluid communication-through the connector-between the medical device and the source of body fluid; and cooperate with openings of other connecting devices to assist in forming mating complexes at either side end of the connector, at least one of the mating complexes having an enlarged space; an extender tube (3602, 3802, 3902) having a first cross-sectional width, the enlarged space having a cross-sectional width that is wider than the first cross-sectional width, and wherein the extender tube is configured to: convey the fluid along a fluid pathway that extends at least part of the way between the first and second openings; and characterized in that the extender tube is configured to: penetrate through at least one of the mating complexes while bypassing the enlarged space; confine fluid within its walls to prevent the fluid from flowing out into the enlarged space of the mating complex; and abut an opening of one of the other connecting devices such that fluid flows directly between the extender tube and the opening of the other connecting device; and wherein a tip of the extender tube comprises a stiff material; and wherein the connector comprises a force exerting structure (3605, 3606, 3609, 3602, 3607, 3612, 3618, 360, 3628) that uses a resilient property to improve a seal, the seal located where the extender tube abuts the opening of the other connecting device; and wherein the extender tube is a spring loaded self adjusting tube. allow fluid communication-through the connector-between the medical device and the source of body fluid; and cooperate with openings of other connecting devices to assist in forming mating complexes at either side end of the connector, at least one of the mating complexes having an enlarged space; convey the fluid along a fluid pathway that extends at least part of the way between the first and second openings; and characterized in that the extender tube is configured to: penetrate through at least one of the mating complexes while bypassing the enlarged space; confine fluid within its walls to prevent the fluid from flowing out into the enlarged space of the mating complex; and abut an opening of one of the other connecting devices such that fluid flows directly between the extender tube and the opening of the other connecting device; and wherein a tip of the extender tube comprises a stiff material; and wherein the connector comprises a force exerting structure (3605, 3606, 3609, 3602, 3607, 3612, 3618, 360, 3628) that uses a resilient property to improve a seal, the seal located where the extender tube abuts the opening of the other connecting device; and wherein the extender tube is a spring loaded self adjusting tube. the extender tube is configured to: penetrate through at least one of the mating complexes while bypassing the enlarged space; confine fluid within its walls to prevent the fluid from flowing out into the enlarged space of the mating complex; and abut an opening of one of the other connecting devices such that fluid flows directly between the extender tube and the opening of the other connecting device; and wherein a tip of the extender tube comprises a stiff material; and wherein the connector comprises a force exerting structure (3605, 3606, 3609, 3602, 3607, 3612, 3618, 360, 3628) that uses a resilient property to improve a seal, the seal located where the extender tube abuts the opening of the other connecting device; and wherein the extender tube is a spring loaded self adjusting tube. penetrate through at least one of the mating complexes while bypassing the enlarged space; confine fluid within its walls to prevent the fluid from flowing out into the enlarged space of the mating complex; and abut an opening of one of the other connecting devices such that fluid flows directly between the extender tube and the opening of the other connecting device; and confine fluid within its walls to prevent the fluid from flowing out into the enlarged space of the mating complex; and abut an opening of one of the other connecting devices such that fluid flows directly between the extender tube and the opening of the other connecting device; and wherein a tip of the extender tube comprises a stiff material; and wherein the connector comprises a force exerting structure (3605, 3606, 3609, 3602, 3607, 3612, 3618, 360, 3628) that uses a resilient property to improve a seal, the seal located where the extender tube abuts the opening of the other connecting device; and wherein the extender tube is a spring loaded self adjusting tube.