Method for operating a motor vehicle, the method including the steps performed by a control device: - determining a first index value from vital data acquired at a first time point, wherein the vital data are received from a sensor device and wherein the vital data describe a physiological parameter of a user of the motor vehicle, - as a function of the first index value, selecting a first actuator of the motor vehicle from a plurality of actuators, - generating a first actuator signal which describes an activation of a first actuator function to be performed by the first actuator and transmitting the first actuator signal to the first actuator, characterised by - after activating the first actuator function acquiring physiological vital data of the user at a second time point by the sensor device (16, S6), and the steps performed by the control device: - determining a second index value from the vital data acquired at the second time point, - comparing the two index values, which each describe a physiological state of the user, - based on a result of the comparison, determining whether the second index value meets an effectiveness criterion, which describes a predetermined degree of improvement of the physiological state by the activated actuator function, - if the second index value meets the effectiveness criterion: activating the first actuator function as soon as an index value is determined which describes the physiological state. - determining a first index value from vital data acquired at a first time point, wherein the vital data are received from a sensor device and wherein the vital data describe a physiological parameter of a user of the motor vehicle, - as a function of the first index value, selecting a first actuator of the motor vehicle from a plurality of actuators, - generating a first actuator signal which describes an activation of a first actuator function to be performed by the first actuator and transmitting the first actuator signal to the first actuator, characterised by - after activating the first actuator function acquiring physiological vital data of the user at a second time point by the sensor device (16, S6), and the steps performed by the control device: - determining a second index value from the vital data acquired at the second time point, - comparing the two index values, which each describe a physiological state of the user, - based on a result of the comparison, determining whether the second index value meets an effectiveness criterion, which describes a predetermined degree of improvement of the physiological state by the activated actuator function, - if the second index value meets the effectiveness criterion: activating the first actuator function as soon as an index value is determined which describes the physiological state. - determining a second index value from the vital data acquired at the second time point, - comparing the two index values, which each describe a physiological state of the user, - based on a result of the comparison, determining whether the second index value meets an effectiveness criterion, which describes a predetermined degree of improvement of the physiological state by the activated actuator function, - if the second index value meets the effectiveness criterion: activating the first actuator function as soon as an index value is determined which describes the physiological state.