mhurhangee/ep-ind-claims huggingface dataset:
A method of performing an injection molding cycle in an injection molding apparatus comprising a manifold that receives an injection fluid, the manifold distributing injection fluid to a fluid delivery channel that delivers the injection fluid under an injection pressure to a gate of a mold cavity and a valve pin having an axis and a tip end, the valve pin being slidably mounted for movement along the axis within the fluid delivery channel, drivably interconnecting the valve pin to an electric motor driven by a source of electrical power or energy in an arrangement wherein the electric motor drives the valve pin along the axis and drives the tip end of the valve pin between a first position where the tip end of the valve pin obstructs the gate to prevent the injection fluid from flowing into the cavity, a second position (COP, COP2, COP3) upstream of the first position wherein the tip end of the valve pin restricts flow of the injection fluid along at least a portion (RP, RP2, RP3) of the length of the drive path extending between the first position and the second position, and a third maximum upstream position where the injection fluid material flows freely without restriction from the tip end of the pin through the first gate, the electric motor being electrically operable to drive the valve pin at one or more intermediate rates of upstream and downstream travel extending between zero and a maximum rate of upstream travel and a maximum rate of downstream travel, characterized in that the method comprises, selecting one or more first lengths of time for the electric motor to operate to drive the valve pin at one or more high rates of downstream travel that are equal to or less than the maximum rate of downstream travel, controllably operating the electric motor to drive the valve pin at the one or more high rates of downstream travel beginning when the valve pin is disposed at the third maximum upstream position during the course of an injection cycle for the one or more selected first lengths of time, controllably operating the motor to drive the valve pin at one or more intermediate rates of downstream travel that are less than the one or more high rates of downstream travel upon expiration of the one or more first selected lengths of time to drive the valve pin downstream to the first position through at least a portion (RP, RP2) of a path of travel of the valve pin extending between the first position and the third position where the tip end of the valve pin restricts flow of the injection fluid through the gate.
A system for use with a subterranean well, the system comprising: a magnetic sensor; a magnetic device which propagates a magnetic field to the magnetic sensor; and a barrier positioned between the magnetic sensor and the magnetic device, the barrier comprising a relatively low magnetic permeability material, wherein the magnetic device comprises a plurality of magnets retained in recesses formed on the outer surface of a sphere. a magnetic sensor; a magnetic device which propagates a magnetic field to the magnetic sensor; and a barrier positioned between the magnetic sensor and the magnetic device, the barrier comprising a relatively low magnetic permeability material, wherein the magnetic device comprises a plurality of magnets retained in recesses formed on the outer surface of a sphere.
A method executed at a terminal (102(a)) for conducting a call, the method comprising: receiving a request at a terminal to initiate a call with another terminal; responsive to the request, forming a communication to be communicated to a service provider for bandwidth parameters (304(a)), the communication including network parameters (306(a)) associated with the terminal wherein the network parameters describe devices and other infrastructure that is to be involved in the call and are configured for use by the service provider in locating one or more of a plurality of clusters; receiving from the service provider bandwidth parameters located from a respective cluster based on the network parameters; and using the bandwidth parameters received from the service provider as part of a model to estimate an amount of bandwidth that is available for the call. receiving a request at a terminal to initiate a call with another terminal; responsive to the request, forming a communication to be communicated to a service provider for bandwidth parameters (304(a)), the communication including network parameters (306(a)) associated with the terminal wherein the network parameters describe devices and other infrastructure that is to be involved in the call and are configured for use by the service provider in locating one or more of a plurality of clusters; receiving from the service provider bandwidth parameters located from a respective cluster based on the network parameters; and using the bandwidth parameters received from the service provider as part of a model to estimate an amount of bandwidth that is available for the call.
A device having a centrifuge that operates discontinuously in batch-type manner for separating syrup from sugar massecuites, comprising a centrifuge housing having a wall and a base, a cylindrical centrifuge drum in the centrifuge housing, drainage openings (41, 42) in the centrifuge housing, a first receiving container for the syrup draining from the drainage openings (41, 42) particularly for receiving green run-off, a second receiving container for the syrup draining from the drainage openings (41, 42) particularly for receiving white run-off, a control device, and valve or shut-off assemblies (71, 72) which are controllable by the control device and are located at or in the drainage openings (41, 42) or in connecting lines (51, 52) from the drainage openings (41, 42) to the receiving containers (61, 62) for the purposes of separating green run-off and white run-off, characterized in that at least one sensor is provided in the transport path of the syrup between the point of impingement of the syrup on the wall of the centrifuge housing and the controllable valve or shut-off assemblies (71, 72), in that the sensor has a measuring device for the measurement of a physical value which is representative of the difference between green run-off and white run-off, in that the control device is configured in such a way that it controls the valve or shut-off assemblies (71, 72) in dependence on the measured values of the physical value transmitted by the sensor, in that a peripheral annular channel is provided in the centrifuge housing underneath the centrifuge drum and above or on the base, in that there is provided in the base a first drainage opening to which a first connecting line to a first receiving container is attached, in that there is provided in the annular channel a second drainage opening to which a second connecting line to a second receiving container is attached, and in that a shut-off assembly is arranged in the second connecting line and is set in such a way that it opens in dependence on the time point at which the syrup arriving at the inner surface of the wall of the centrifuge housing from the centrifuge drum changes from green run-off to white run-off.
Column shoe for securing building elements of concrete such as concrete columns to a base, wherein the column shoe comprising a bolt housing comprising a base plate having a bolt hole for an anchor bolt projecting from the base and comprising an upper structure, and a securing means for securing to the bolt housing an attachment unit such as a main bond for securing the column shoe and a building element of concrete together, wherein the securing means is in the form of a separate fastening part, characterized in that the securing means for securing to the bolt housing an attachment unit is configured for securing the attachment unit to the bolt housing by pressing the attachment unit between the upper structure of the bolt housing and the securing means, and in that at least one of the upper structure of the bolt housing and the securing means in the form of a separate fastening part is provided with a seat for guiding an attachment unit into a predetermined position and/or for keeping an attachment unit in a predetermined position with respect to the bolt housing, wherein the seat is configured for guiding an attachment unit in the form of a steel bar into such predetermined position and/or for keeping an attachment unit in the form of a steel bar in such predetermined position where the attachment unit in the form of a steel bar is at least partly coaxial with the bolt hole in the base plate.
A seating system for an aircraft, comprising: a seat frame configured to be mounted to a floor of the aircraft and defining at least one seat position, each seat position including a seat back and a seat pan coupled to the seat frame; an adaptive energy absorption device disposed beneath the seat pan of the at least one seat position, the adaptive energy absorption device comprising a plurality of fluidly coupled inflatable elastic bladders (122a-c) and at least one constrictor valve for allowing fluid to flow from one of the plurality of inflatable elastic bladders in response to predetermined pressure on the adaptive energy absorption device from the seat pan of the at least one seat position; and a fluid supply source fluidly coupled to at least one of the plurality of inflatable elastic bladders operable for outputting a positive flow of fluid to the at least one inflatable elastic bladder; characterized in that: the adaptive energy absorption device is detached from the seat frame to allow removal from beneath the seat pan of the at least one seat position for use as an emergency flotation device; and the seat pan is pivotally and/or translatably coupled to the seat frame and the adaptive energy absorption device is configured to be positioned in direct physical contact with the floor and the seat pan of the at least one seat position to provide energy absorption functionality. a seat frame configured to be mounted to a floor of the aircraft and defining at least one seat position, each seat position including a seat back and a seat pan coupled to the seat frame; an adaptive energy absorption device disposed beneath the seat pan of the at least one seat position, the adaptive energy absorption device comprising a plurality of fluidly coupled inflatable elastic bladders (122a-c) and at least one constrictor valve for allowing fluid to flow from one of the plurality of inflatable elastic bladders in response to predetermined pressure on the adaptive energy absorption device from the seat pan of the at least one seat position; and a fluid supply source fluidly coupled to at least one of the plurality of inflatable elastic bladders operable for outputting a positive flow of fluid to the at least one inflatable elastic bladder; characterized in that: the adaptive energy absorption device is detached from the seat frame to allow removal from beneath the seat pan of the at least one seat position for use as an emergency flotation device; and the seat pan is pivotally and/or translatably coupled to the seat frame and the adaptive energy absorption device is configured to be positioned in direct physical contact with the floor and the seat pan of the at least one seat position to provide energy absorption functionality.
A joint with adjustable angular range for a knee brace or other orthopedic braces with two uprights or rods (11, 12) having respective shaped ends, which can be fitted as auxiliary supports for the joints of the human body such as the knee, the ankle, the elbow or similar, wherein the pivot of these two uprights or rods (11, 12) comprises two plates (13, 14), namely an outer plate and an inner plate, connected to each other at four locations, which represent the four joint points of an articulated four-sided figure between the lower upright and the upper upright, said joint further comprises two wedges (19, 20) to be inserted between said plates (13, 14) and said uprights or rods (11, 12), said wedges (19, 20) having different shapes according to a given angular range to be obtained, characterised in that each of said wedges (19, 20) is provided with at least one groove and a lowered area, each lowered area accommodating a tooth of respective tabs located at the two ends of a spring fixed to said outer plate, said spring being positioned at the level of a central insert, whereby said wedges (19, 20), said spring and said central insert cooperate with the shaped end of said uprights or rods to delimit the angular range of motion of the joint.
Device for extracorporeal temperature control of patients, with a transfer of heat between a fluid and a transfer medium, comprising - a primary circuit having a primary body (102, 201) for receiving the fluid, and - a secondary circuit having a secondary body (104, 200) which comprises connections (240, 242) for supplying and removing the transfer medium, the secondary body (104, 200) being fastenable to the primary body (102, 201), the secondary body (104, 200) being made at least substantially of plastics material, and the primary body (102, 201) comprising a boundary element for transferring heat to the transfer medium, the boundary element having an area of less than 1m*m, characterised in that the secondary body (104, 200) has at least one nozzle for forming an impact flow which, when the secondary body (104, 200) is fastened to the primary body (102, 201), is directed in the direction of the primary body (102, 201). - a primary circuit having a primary body (102, 201) for receiving the fluid, and - a secondary circuit having a secondary body (104, 200) which comprises connections (240, 242) for supplying and removing the transfer medium, the secondary body (104, 200) being fastenable to the primary body (102, 201), the secondary body (104, 200) being made at least substantially of plastics material, and the primary body (102, 201) comprising a boundary element for transferring heat to the transfer medium, the boundary element having an area of less than 1m*m, characterised in that the secondary body (104, 200) has at least one nozzle for forming an impact flow which, when the secondary body (104, 200) is fastened to the primary body (102, 201), is directed in the direction of the primary body (102, 201).
A method of diagnosing or predicting the likelihood of occurrence of preeclampsia in a subject, the method comprising: measuring differences in copeptin levels in a sample collected from a subject during the first trimester of pregnancy compared to a control using an antibody detection assay, wherein the sample is blood, serum, plasma or urine, and wherein an increase in copeptin levels of about 1/4 fold compared to a control is predictive of the occurrence of preeclampsia during the subject's pregnancy. measuring differences in copeptin levels in a sample collected from a subject during the first trimester of pregnancy compared to a control using an antibody detection assay, wherein the sample is blood, serum, plasma or urine, and wherein an increase in copeptin levels of about 1/4 fold compared to a control is predictive of the occurrence of preeclampsia during the subject's pregnancy.
A compound represented by the following general formula, and the pharmaceutically acceptable salt thereof: wherein R 1 is selected from the group consisting of a hydrogen atom, C 1 -C 6 alkyl group, C 2 -C 6 alkyl ketone group and -(CH 2) n -Q, of which Q is an ether group or amine group substituted with C 1 -C 6 lower alkyl group; R 2 is a hydrogen atom, or an ether group or thio group substituted with C 1 -C 6 alkyl group; R 3 is a group selected from following substituents of general formula (Ia), (Ib), (Ic) or (Id), wherein R' is a hydrogen atom, or C 1 -C 6 alkyl group, X is O, S, or amine group unsubstituted or substituted with R", of which R" is a benzyl group substituted with ester group or carboxyl group, n is an integer of 0-9; wherein R'" is selected from a hydrogen atom, C 1 -C 6 alkyl group or benzyl group, n is an integer of 0-9; wherein P 1, P 2 is independently selected from the group consisting of a hydrogen atom, C 1 -C 6 alkyl group, phenyl group and benzyl group, n is an integer of 0-9; wherein X is C or N atom, m is an integer of 0 or 1, Q is a phenyl group substituted with C 1 -C 3 alkyl group, halogen atom, or nitro group, n is an integer of 0-9. R 1 is selected from the group consisting of a hydrogen atom, C 1 -C 6 alkyl group, C 2 -C 6 alkyl ketone group and -(CH 2) n -Q, of which Q is an ether group or amine group substituted with C 1 -C 6 lower alkyl group; R 2 is a hydrogen atom, or an ether group or thio group substituted with C 1 -C 6 alkyl group; R 3 is a group selected from following substituents of general formula (Ia), (Ib), (Ic) or (Id), wherein R' is a hydrogen atom, or C 1 -C 6 alkyl group, X is O, S, or amine group unsubstituted or substituted with R", of which R" is a benzyl group substituted with ester group or carboxyl group, n is an integer of 0-9; wherein R'" is selected from a hydrogen atom, C 1 -C 6 alkyl group or benzyl group, n is an integer of 0-9; wherein P 1, P 2 is independently selected from the group consisting of a hydrogen atom, C 1 -C 6 alkyl group, phenyl group and benzyl group, n is an integer of 0-9; wherein X is C or N atom, m is an integer of 0 or 1, Q is a phenyl group substituted with C 1 -C 3 alkyl group, halogen atom, or nitro group, n is an integer of 0-9. wherein R' is a hydrogen atom, or C 1 -C 6 alkyl group, X is O, S, or amine group unsubstituted or substituted with R", of which R" is a benzyl group substituted with ester group or carboxyl group, n is an integer of 0-9; wherein R'" is selected from a hydrogen atom, C 1 -C 6 alkyl group or benzyl group, n is an integer of 0-9; wherein P 1, P 2 is independently selected from the group consisting of a hydrogen atom, C 1 -C 6 alkyl group, phenyl group and benzyl group, n is an integer of 0-9; wherein X is C or N atom, m is an integer of 0 or 1, Q is a phenyl group substituted with C 1 -C 3 alkyl group, halogen atom, or nitro group, n is an integer of 0-9.
A hoisting machine arrangement comprising a rope drum, which has a driven gearwheel; a hoisting motor for driving the rope drum; and a gear between the hoisting motor and the rope drum the gear having a body and a driving gearwheel, the driving gearwheel of the gear being coupled to the driven gearwheel of the rope drum, wherein the gear body has: - a first drilling, which is arranged for fitting a shaft of the driving gearwheel; and - a second drilling, which is parallel to the first drilling and arranged for fitting a shaft of the rope drum, a shaft seating attached to the shaft or a shaft extension at an end of the rope drum, characterized in that the - the driven gearwheel is formed or fastened to the inner circumference of the rope drum, to an edge of the rope drum. - a first drilling, which is arranged for fitting a shaft of the driving gearwheel; and - a second drilling, which is parallel to the first drilling and arranged for fitting a shaft of the rope drum, a shaft seating attached to the shaft or a shaft extension at an end of the rope drum, - the driven gearwheel is formed or fastened to the inner circumference of the rope drum, to an edge of the rope drum.
A process for the preparation of water expandable polymer beads, which process comprises the steps of: a) providing a starting composition comprising styrene and a cross-linking agent containing a hydrophilic polymer chain and at least two hydrolysable end-groups having a carbon-to-carbon double bond, b) prepolymerizing the starting composition to obtain a prepolymer composition, c) adding an aqueous dispersion of a modifier-free nanoclay to the prepolymer composition to obtain an inverse emulsion, d) suspending the inverse emulsion obtained by step c) in an aqueous medium to yield an aqueous suspension of suspended droplets and e) polymerizing the monomers in the droplets of the suspension obtained by step d) to obtain the water expandable polymer beads. a) providing a starting composition comprising styrene and a cross-linking agent containing a hydrophilic polymer chain and at least two hydrolysable end-groups having a carbon-to-carbon double bond, b) prepolymerizing the starting composition to obtain a prepolymer composition, c) adding an aqueous dispersion of a modifier-free nanoclay to the prepolymer composition to obtain an inverse emulsion, d) suspending the inverse emulsion obtained by step c) in an aqueous medium to yield an aqueous suspension of suspended droplets and e) polymerizing the monomers in the droplets of the suspension obtained by step d) to obtain the water expandable polymer beads.
A tire comprising an RFID tag for traceability capable of communicating from at least an inner cavity side of the tire which is disposed in a peripheral region of a bead core; and a carcass ply which extends from one bead core to another bead core and is folded back around the bead core; characterized in that the tire further comprises a chafer which is arranged so as to cover the carcass ply around the bead core, wherein the RFID tag for traceability is disposed between the carcass ply and the chafer.
A method for producing a biodegradable implant having a body containing predominantly iron, comprising the following steps: a) providing the body of the implant, b) incorporating hydrogen into at least a portion of the structure of the implant body near the surface by pickling by means of an acid, wherein following the pickling step for incorporating the hydrogen at least a portion of the implant body is immersed in an acidic to alkaline electrolyte system and is then connected to the cathode of a voltage source. a) providing the body of the implant, b) incorporating hydrogen into at least a portion of the structure of the implant body near the surface by pickling by means of an acid, wherein following the pickling step for incorporating the hydrogen at least a portion of the implant body is immersed in an acidic to alkaline electrolyte system and is then connected to the cathode of a voltage source.
A pharmaceutical composition, comprising a modified MT-SP1 protease, or a catalytically active portion thereof, for use in the treatment of a disease or disorder selected from among an inflammatory disorder, a neurodegenerative disorder and a cardiovascular disorder, wherein: the modified MT-SP1 protease, or a catalytically active portion thereof, cleaves any one or more target substrates of a complement pathway such that complement activation in a pathway comprising the target substrate is inhibited; the target substrate is a complement protein; the inhibition of complement activation leads to a reduction of inflammatory symptoms associated with the disease or disorder; the modified MT-SP1 protease or a catalytically active portion thereof comprises one or more modifications that increases one or both of specificity for a target substrate and activity towards a target substrate compared to an unmodified MT-SP1 protease; and the modified MT-SP1 protease or a catalytically active portion thereof comprises one or more modification(s) selected from among I41T, I41A, I41L, I41F, I41D, I41E, Q175H, Q175L, Q175W, Q175Y, and Q175K, based on chymotrypsin numbering. the modified MT-SP1 protease, or a catalytically active portion thereof, cleaves any one or more target substrates of a complement pathway such that complement activation in a pathway comprising the target substrate is inhibited; the target substrate is a complement protein; the inhibition of complement activation leads to a reduction of inflammatory symptoms associated with the disease or disorder; the modified MT-SP1 protease or a catalytically active portion thereof comprises one or more modifications that increases one or both of specificity for a target substrate and activity towards a target substrate compared to an unmodified MT-SP1 protease; and the modified MT-SP1 protease or a catalytically active portion thereof comprises one or more modification(s) selected from among I41T, I41A, I41L, I41F, I41D, I41E, Q175H, Q175L, Q175W, Q175Y, and Q175K, based on chymotrypsin numbering.