mhurhangee/ep-ind-claims huggingface dataset:
A method for predicting the likelihood that a patient's cancer will respond to chemotherapy comprising treatment with a taxane or taxane derivative comprising steps of: providing a cancer sample that has been removed from a breast, ovarian or lung cancer patient; determining whether TLE3 is expressed in the cancer sample; and predicting the likelihood that the patient's cancer will respond to chemotherapy comprising treatment with a taxane or taxane derivative based upon the presence or absence of TLE3 expression in the cancer sample, wherein the presence of TLE3 expression is predictive that the cancer will respond and/or the absence of TLE3 expression is predictive that the cancer will not respond. providing a cancer sample that has been removed from a breast, ovarian or lung cancer patient; determining whether TLE3 is expressed in the cancer sample; and predicting the likelihood that the patient's cancer will respond to chemotherapy comprising treatment with a taxane or taxane derivative based upon the presence or absence of TLE3 expression in the cancer sample, wherein the presence of TLE3 expression is predictive that the cancer will respond and/or the absence of TLE3 expression is predictive that the cancer will not respond.
A catalyst composition for hydrogenation comprising: titanocene dichloride; an organometal compound comprising one or two or more elements selected from the group consisting of Li, Na, K, Mg, Zn, Al, and Ca; an unsaturated compound; and a polar compound selected from alcohol compounds, ether compounds, thioether compounds, ketone compounds, sulfoxide compounds, carboxylic acid compounds, carboxylate compounds, aldehyde compounds, lactam compounds, lactone compounds, amine compounds, amide compounds, nitrile compounds, epoxy compounds and oxime compounds, wherein a molar ratio of the unsaturated compound to the titanocene dichloride is 0.1 or more and 8.0 or less, a molar ratio of the polar compound to the titanocene dichloride is 0.01 or more and 2.0 or less, and wherein the unsaturated compound is an unsaturated polymer having a number average molecular weight of more than 400 which has a ratio of an olefinically unsaturated double bond content of a side chain comprised in the unsaturated compound to a total olefinically unsaturated double bond content of the unsaturated compound of 0.25 or more and 1.00 or less, or is an unsaturated compound having a molecular weight of 400 or less, which is a monomer selected from conjugated dienes having 4 to 12 carbon atoms, monoterpene, vinyl aromatic compounds, norbornadiene, cyclopentadiene, cyclohexadiene, 2,3-dihydrodicyclopentadiene and acetylenes, or a polymer prepared by polymerizing one or more of these monomers, or is a combination of the unsaturated polymer and the unsaturated compound. titanocene dichloride; an organometal compound comprising one or two or more elements selected from the group consisting of Li, Na, K, Mg, Zn, Al, and Ca; an unsaturated compound; and a polar compound selected from alcohol compounds, ether compounds, thioether compounds, ketone compounds, sulfoxide compounds, carboxylic acid compounds, carboxylate compounds, aldehyde compounds, lactam compounds, lactone compounds, amine compounds, amide compounds, nitrile compounds, epoxy compounds and oxime compounds, wherein a molar ratio of the unsaturated compound to the titanocene dichloride is 0.1 or more and 8.0 or less, a molar ratio of the polar compound to the titanocene dichloride is 0.01 or more and 2.0 or less, and wherein the unsaturated compound is an unsaturated polymer having a number average molecular weight of more than 400 which has a ratio of an olefinically unsaturated double bond content of a side chain comprised in the unsaturated compound to a total olefinically unsaturated double bond content of the unsaturated compound of 0.25 or more and 1.00 or less, or is an unsaturated compound having a molecular weight of 400 or less, which is a monomer selected from conjugated dienes having 4 to 12 carbon atoms, monoterpene, vinyl aromatic compounds, norbornadiene, cyclopentadiene, cyclohexadiene, 2,3-dihydrodicyclopentadiene and acetylenes, or a polymer prepared by polymerizing one or more of these monomers, or is a combination of the unsaturated polymer and the unsaturated compound.
Motor vehicle comprising: - a chassis comprising a longitudinal member; - a support which is intended to support an engine in an engine compartment; the support being fixed directly to the longitudinal member; said vehicle being characterized in that - the vehicle comprises a connection component which connects the support to a first structure of the chassis which is located above the longitudinal member; - the connection component comprises: -- a main body; -- a first fixing screw which connects the support to the connection component; -- a second fixing screw which connects the chassis to the connection component; -- at least one lateral wing which is arranged along the main body; characterized in that the connection component further comprises a sliding member which is produced in the main body and which receives the first and second fixing screws (41, 42). - a chassis comprising a longitudinal member; - a support which is intended to support an engine in an engine compartment; the support being fixed directly to the longitudinal member; - the vehicle comprises a connection component which connects the support to a first structure of the chassis which is located above the longitudinal member; - the connection component comprises: -- a main body; -- a first fixing screw which connects the support to the connection component; -- a second fixing screw which connects the chassis to the connection component; -- at least one lateral wing which is arranged along the main body; -- a main body; -- a first fixing screw which connects the support to the connection component; -- a second fixing screw which connects the chassis to the connection component; -- at least one lateral wing which is arranged along the main body;
Sliding door fitting for a sliding door cabinet, wherein a first of at least two sliding door wings (21, 21') can be moved from a flush position, in which the front side of the first sliding door wing is substantially flush with the front side of the second sliding door wing, via an offset position, in which the front side of the first sliding door wing is offset transversely to the direction of movement with respect to the front side of the second sliding door wing, in the direction of movement over the second sliding door wing into an open position, comprising a control lever for driving the first sliding door wing from an initial movement path of the first sliding door wing in the initial phase of the opening movement or in the end phase of the closing movement by an offset distance into the offset position or into the flush position, wherein the control lever comprises an output arm which engages a slide which can be moved transversely to the extension of a slide rail on a carriage which can be moved along the slide rail, and a drive arm (7, 8) which cooperates with a stop (13, 14), wherein the output arm is longer than the drive arm and wherein the lengths of the drive arm (7, 8) and output arm are dimensioned such that the offset distance is at least double as large as the initial movement path, characterized in that the control lever is an angle lever with a pivot bearing which is borne on the body (22, 34), wherein the output arm is at least double as long as the drive arm (7, 8) and that the stop (13, 14) is fixed to the carriage.
Mould suitable for thermoforming a product from a heated plastic film, comprising a base plate and a plurality of forming areas, wherein each forming area comprises: • a cavity in the base plate; • a cutting sleeve; • a forming sleeve; • a forming base; and • first heat means, wherein the cutting sleeve has a jacket-like shape, the cutting sleeve being placed in the base plate cavity, the forming sleeve being placed in the cutting sleeve, and the forming base being placed in the forming sleeve, wherein the first heat means comprise: a first heating element configured to heat the forming sleeve, and/or first thermal insulating means comprising a first thermal insulator configured to block or limit a heat flow from the forming sleeve and/or from the forming base towards the base plate and/or towards the cutting sleeve and/or towards a knock-out pin underneath the forming base; so that each forming area comprises first heat means for heating or keeping heated the forming sleeve relative to the base plate, characterized in that the first heating element takes a jacket-like or annular form and is placed around or in the forming sleeve, wherein the first thermal insulator comprises a jacket-like or annular element which is placed around the first heating element. • a cavity in the base plate; • a cutting sleeve; • a forming sleeve; • a forming base; and • first heat means, a first heating element configured to heat the forming sleeve, and/or first thermal insulating means comprising a first thermal insulator configured to block or limit a heat flow from the forming sleeve and/or from the forming base towards the base plate and/or towards the cutting sleeve and/or towards a knock-out pin underneath the forming base; so that each forming area comprises first heat means for heating or keeping heated the forming sleeve relative to the base plate, characterized in that the first heating element takes a jacket-like or annular form and is placed around or in the forming sleeve, wherein the first thermal insulator comprises a jacket-like or annular element which is placed around the first heating element.
A movable carrier (1, 1a, 1b, 2), comprising: a bottom frame assembly; a first support member having a first end portion and a second end portion, wherein the first end portion is connected with the bottom frame assembly; and at least one link assembly (13, 13a) comprising a link member (131, 131a, 131b), a first connect member, a second connect member, and two adapter members (133, 133a), wherein the link member (131, 131a, 131b) is disposed at the second end portion of the first support member, the first connect member and the second connect member are disposed on the link member (131, 131a, 131b) and connected to the second end portion of the first support member through the link member (131, 131a, 131b), the adapter members (133, 133a) are disposed corresponding to ends of the first connect member and the second connect member, and each of the adapter members (133, 133a) has an adapter portion (1331, 1331a); wherein, in the process of changing positions of the first connect member and the second connect member relative to the link member (131, 131a, 131b), the adapter portions (1331, 1331a) are all oriented to the same direction, wherein the link member (131, 131a, 131b) comprises a link portion, and the first connect member and the second connect member are pivotally connected to the link portion, characterized in that the movable carrier (1, 1a, 1b, 2) comprises two of the link assemblies (13, 13a) disposed at two sides of the movable carrier (1, 1a, 1b, 2). a bottom frame assembly; a first support member having a first end portion and a second end portion, wherein the first end portion is connected with the bottom frame assembly; and at least one link assembly (13, 13a) comprising a link member (131, 131a, 131b), a first connect member, a second connect member, and two adapter members (133, 133a), wherein the link member (131, 131a, 131b) is disposed at the second end portion of the first support member, the first connect member and the second connect member are disposed on the link member (131, 131a, 131b) and connected to the second end portion of the first support member through the link member (131, 131a, 131b), the adapter members (133, 133a) are disposed corresponding to ends of the first connect member and the second connect member, and each of the adapter members (133, 133a) has an adapter portion (1331, 1331a); wherein, in the process of changing positions of the first connect member and the second connect member relative to the link member (131, 131a, 131b), the adapter portions (1331, 1331a) are all oriented to the same direction, wherein the link member (131, 131a, 131b) comprises a link portion, and the first connect member and the second connect member are pivotally connected to the link portion, characterized in that the movable carrier (1, 1a, 1b, 2) comprises two of the link assemblies (13, 13a) disposed at two sides of the movable carrier (1, 1a, 1b, 2).
A container for containing a beverage base material, said container including a base body and a cover, said base body comprising a beverage base material chamber defined by a chamber bottom and a chamber wall at the perimeter of the chamber bottom, the chamber of the base body being open at the side opposite the chamber bottom, said chamber wall being provided with a sealing surface at its free end opposite the chamber bottom, the cover being attached to the sealing surface of the chamber wall for closing the beverage base material chamber, said container comprising an intake opening for taking in an extraction medium to the beverage base material chamber and a dispensing opening for dispensing a beverage from the beverage base material chamber, characterized in that the container furthermore comprises an elongated handle extending in a direction having a radial component outward from the beverage base material chamber, said elongated handle being integral with the base body and comprising a handle bottom and a handle sealing flange which is flush with the sealing surface of the chamber wall, said handle being provided with an outlet channel extending from an upstream channel inlet communicating with the dispensing opening to a downstream channel outlet provided at the free end of the handle, said cover being furthermore attached to the sealing flange of the handle for closing the outlet channel in a direction opposite the handle bottom.
A zoom lens system, consisting of, in order from an object side to an image side: a first lens group having negative power; a second lens group having positive power, and a third lens group having positive power, wherein the first lens group includes at least two negative lenses (L1, L2), when zooming, the first lens group is fixed relative to an imaging surface, the second lens group is configured to move along an optical axis to change an angle of view, the third lens group is fixed relative to the imaging surface and a total angle of view at a wide angle extremity is at least 120 degrees, and characterized in that the following condition is satisfied: − 1.1 < 1 / fG 1 / 2 × fW × tan wW / 2 < − 0.5 where: fG1 is a focal length along a d-line of the first lens group fW is a focal length along a d-line of a wide angle extremity; and wW is a half angle of view at the wide angle extremity. a first lens group having negative power; a second lens group having positive power, and a third lens group having positive power, wherein the first lens group includes at least two negative lenses (L1, L2), when zooming, the first lens group is fixed relative to an imaging surface, the second lens group is configured to move along an optical axis to change an angle of view, the third lens group is fixed relative to the imaging surface and a total angle of view at a wide angle extremity is at least 120 degrees, and characterized in that the following condition is satisfied: − 1.1 < 1 / fG 1 / 2 × fW × tan wW / 2 < − 0.5 where: fG1 is a focal length along a d-line of the first lens group fW is a focal length along a d-line of a wide angle extremity; and wW is a half angle of view at the wide angle extremity. fG1 is a focal length along a d-line of the first lens group fW is a focal length along a d-line of a wide angle extremity; and wW is a half angle of view at the wide angle extremity.
A binding protein comprising a binding region capable of binding to Aβ 42 prefibrillar oligomers with β-structure, said binding protein is an antibody or an antibody fragment which comprises: a. a variable heavy domain having: the amino acid SEQ ID NO:1 GFSLSTFGSGVS as CDR1, the amino acid SEQ ID NO:2 HIYWDDDKH as CDR2, and the amino acid sequence SEQ ID NO: 3 RESHYYGSGYYFDY as CDR3, and b. a variable light domain having: the amino acid SEQ ID NO:4 RASSSVSYMH as CDR1, the amino acid SEQ ID NO:5 ATSNLAS as CDR2, and the amino acid sequence SEQ ID NO:6 QQWRSDPLT as CDR3. a. a variable heavy domain having: the amino acid SEQ ID NO:1 GFSLSTFGSGVS as CDR1, the amino acid SEQ ID NO:2 HIYWDDDKH as CDR2, and the amino acid sequence SEQ ID NO: 3 RESHYYGSGYYFDY as CDR3, and the amino acid SEQ ID NO:1 GFSLSTFGSGVS as CDR1, the amino acid SEQ ID NO:2 HIYWDDDKH as CDR2, and the amino acid sequence SEQ ID NO: 3 RESHYYGSGYYFDY as CDR3, and b. a variable light domain having: the amino acid SEQ ID NO:4 RASSSVSYMH as CDR1, the amino acid SEQ ID NO:5 ATSNLAS as CDR2, and the amino acid sequence SEQ ID NO:6 QQWRSDPLT as CDR3. the amino acid SEQ ID NO:4 RASSSVSYMH as CDR1, the amino acid SEQ ID NO:5 ATSNLAS as CDR2, and
A vehicle comprising a control system, the vehicle comprising a first sensor arrangement disposed at a first orientation relative to the host vehicle and at least one secondary sensor arrangement, each additional sensor arrangement being disposed at an orientation relative to the host vehicle that is different to the first orientation, the control system having one or more controllers configured to: receive first sensor information from the first sensor arrangement; receive secondary sensor information from each additional sensor arrangement; determine a lateral position of the vehicle relative to a roadway using the additional sensor information if all or part of the first sensor information is interrupted; and provide an output in dependence on the determined lateral position; wherein each sensor arrangement comprises a primary sensor which is part of a primary sensor system and a secondary sensor which is part of a secondary sensor system; and wherein independent power supplies (212. 222) are provided for primary and secondary sensors within each sensor arrangement. receive first sensor information from the first sensor arrangement; receive secondary sensor information from each additional sensor arrangement; determine a lateral position of the vehicle relative to a roadway using the additional sensor information if all or part of the first sensor information is interrupted; and provide an output in dependence on the determined lateral position; wherein each sensor arrangement comprises a primary sensor which is part of a primary sensor system and a secondary sensor which is part of a secondary sensor system; and wherein independent power supplies (212. 222) are provided for primary and secondary sensors within each sensor arrangement.
Computer system with at least one interface, in particular at least one USB Type-C interface, including - at least one voltage monitoring device, and - at least one interface control device including a signaling circuit, wherein the interface control device is configured to restrict a power output via the interface to a predetermined power level if the voltage monitoring device detects a drop of a supply voltage of the computer system below a first threshold value, and the signaling circuit is configured to signalize the restriction of the power output to a peripheral device. - at least one voltage monitoring device, and - at least one interface control device including a signaling circuit,
A method for producing picture data for a representation of an instrument on a display device, wherein the method comprises the following steps: - detecting position measurement data by at least two position sensors arranged on the instrument, - determining a movement condition of the instrument on the basis of the acquired position measurement data, - filtering the acquired position measurement data on the basis of the determined movement condition and - providing a picture data set for a representation of the instrument on the display device, at least on the basis of the filtered position measurement data, said picture data set being configured to represent the instrument on the display device, - wherein each of the position sensors which are arranged on the instrument is configured to output position measurement data, from which data an instrument operating point is determined in each case by way of a data processing device, wherein the magnitude of the distance between the two determined instrument operating points is indicated as a plausibility value, and - the instrument operating point is provided with a circle of a ball by way of the data processing device for representation on the display device, the radius of said circle corresponding to the plausibility value. - detecting position measurement data by at least two position sensors arranged on the instrument, - determining a movement condition of the instrument on the basis of the acquired position measurement data, - filtering the acquired position measurement data on the basis of the determined movement condition and - providing a picture data set for a representation of the instrument on the display device, at least on the basis of the filtered position measurement data, said picture data set being configured to represent the instrument on the display device, - wherein each of the position sensors which are arranged on the instrument is configured to output position measurement data, from which data an instrument operating point is determined in each case by way of a data processing device, wherein the magnitude of the distance between the two determined instrument operating points is indicated as a plausibility value, and - the instrument operating point is provided with a circle of a ball by way of the data processing device for representation on the display device, the radius of said circle corresponding to the plausibility value.
Electrical contact assembly for low current use, comprising: • two fixed contacts from a first contact material, • a movable contact connectable with the fixed contacts in a closed and open position, wherein the movable contact which bridges the fixed contact consists of a contact holder and at least one contact piece (KS, KQ) from the second contact material, • a contact holder supporting the at least one contact piece (KS, KQ) on the movable contact, wherein the movable contact is movable in a longitudinal direction and operable on the fixed contacts, wherein a material pairing of the contact-making elements is designed in such a way that the first contact material consists of a metallic conductor material, preferably of a copper or silver alloy, and the second contact material has a composition including minimum 70% and maximum 100% weight of carbon material, wherein at least one contact piece (KS, KQ) is available on the movable contact, which bridges the respective fixed contacts. • two fixed contacts from a first contact material, • a movable contact connectable with the fixed contacts in a closed and open position, wherein the movable contact which bridges the fixed contact consists of a contact holder and at least one contact piece (KS, KQ) from the second contact material, • a contact holder supporting the at least one contact piece (KS, KQ) on the movable contact, wherein the movable contact is movable in a longitudinal direction and operable on the fixed contacts,