A system for mechanosynthetic manufacture with a predefined reliability, the system being configured for receiving a build sequence comprising ordered steps of mechanosynthetic reactions, predefined trajectories of said mechanosynthetic reactions, and for which the reliability of said mechanosynthetic reactions has been determined to be capable of manufacturing a specified workpiece to a predefined degree of reliability, wherein the system comprises: a three-dimensional, atomically-precise diamondoid workpiece; a presentation surface which provides feedstock; an atomically-precise tip; a computer having access to said received build sequence; and a positional device, connected to the computer, and configured to position said atomically-precise tip with respect to said feedstock and said workpiece, and configured to be operated by the computer according to said received build sequence to carry out the mechanosynthetic reactions using steps comprising: approximating one or more active atoms of said atomically-precise tip with said feedstock so that a tip-feedstock bond between said atomically-precise tip and feedstock is formed; withdrawing said atomically-precise tip, wherein said tip-feedstock bond causes said feedstock to be withdrawn with said atomically-precise tip; positioning said atomically-precise tip with respect to said workpiece, via one respective trajectory, such that said feedstock which is bonded to said atomically-precise tip forms a feedstock-workpiece bond with said workpiece; and withdrawing said atomically-precise tip, thereby breaking said tip-feedstock bond and leaving said feedstock bonded to said workpiece. a three-dimensional, atomically-precise diamondoid workpiece; a presentation surface which provides feedstock; an atomically-precise tip; a computer having access to said received build sequence; and a positional device, connected to the computer, and configured to position said atomically-precise tip with respect to said feedstock and said workpiece, and configured to be operated by the computer according to said received build sequence to carry out the mechanosynthetic reactions using steps comprising: approximating one or more active atoms of said atomically-precise tip with said feedstock so that a tip-feedstock bond between said atomically-precise tip and feedstock is formed; withdrawing said atomically-precise tip, wherein said tip-feedstock bond causes said feedstock to be withdrawn with said atomically-precise tip; positioning said atomically-precise tip with respect to said workpiece, via one respective trajectory, such that said feedstock which is bonded to said atomically-precise tip forms a feedstock-workpiece bond with said workpiece; and withdrawing said atomically-precise tip, thereby breaking said tip-feedstock bond and leaving said feedstock bonded to said workpiece. approximating one or more active atoms of said atomically-precise tip with said feedstock so that a tip-feedstock bond between said atomically-precise tip and feedstock is formed; withdrawing said atomically-precise tip, wherein said tip-feedstock bond causes said feedstock to be withdrawn with said atomically-precise tip; positioning said atomically-precise tip with respect to said workpiece, via one respective trajectory, such that said feedstock which is bonded to said atomically-precise tip forms a feedstock-workpiece bond with said workpiece; and withdrawing said atomically-precise tip, thereby breaking said tip-feedstock bond and leaving said feedstock bonded to said workpiece.