An apparatus (8, 8') for closing a tubular structure within a patient's body, comprising: a tubular member (10, 10', 310, 410) comprising a proximal end (12, 12') including a hub (50, 50', 350, 450), a distal end (14, 14') including a sharpened distal tip (15, 15'), a lumen having an oblong cross-section extending proximally from the distal end, and defining a longitudinal axis between the proximal and distal ends; a clip (20, 120, 120', 220, 320) compressible between a relaxed state in which a plurality of tines (22, 24, 122, 124, 122', 124', 222, 224, 322, 324) of the clip are shaped to engage and close a tubular structure within a patient's body, and a stressed state in which the tines are compressed to allow the clip to be loaded into the lumen in a predetermined orientation about the longitudinal axis; and a pusher member (30, 30') comprising a proximal end and a distal end sized for advancement within the lumen for deploying the clip from the sharpened distal tip such that the tines engage and close a tubular structure through which the tubular member is directed, wherein the plurality of tines comprise a pair of distal tines (22, 122, 122', 222, 322) extending from a first end of a central region (26, 126, 126', 226, 326) of the clip and a pair of proximal tines (24, 124, 124, 124', 224, 324) extend from a second end of the central region, the apparatus further characterized in that the distal tines, proximal tines, and the central region define a plane and lie within the plane in the relaxed configuration, and the distal and proximal tines remain within the plane when the tines are compressed into the stressed state. a tubular member (10, 10', 310, 410) comprising a proximal end (12, 12') including a hub (50, 50', 350, 450), a distal end (14, 14') including a sharpened distal tip (15, 15'), a lumen having an oblong cross-section extending proximally from the distal end, and defining a longitudinal axis between the proximal and distal ends; a clip (20, 120, 120', 220, 320) compressible between a relaxed state in which a plurality of tines (22, 24, 122, 124, 122', 124', 222, 224, 322, 324) of the clip are shaped to engage and close a tubular structure within a patient's body, and a stressed state in which the tines are compressed to allow the clip to be loaded into the lumen in a predetermined orientation about the longitudinal axis; and a pusher member (30, 30') comprising a proximal end and a distal end sized for advancement within the lumen for deploying the clip from the sharpened distal tip such that the tines engage and close a tubular structure through which the tubular member is directed, wherein the plurality of tines comprise a pair of distal tines (22, 122, 122', 222, 322) extending from a first end of a central region (26, 126, 126', 226, 326) of the clip and a pair of proximal tines (24, 124, 124, 124', 224, 324) extend from a second end of the central region, the apparatus further characterized in that the distal tines, proximal tines, and the central region define a plane and lie within the plane in the relaxed configuration, and the distal and proximal tines remain within the plane when the tines are compressed into the stressed state.