mhurhangee/ep-ind-claims huggingface dataset:
A minimally invasive robotic surgical assembly (500,600) comprising: a base; a main shaft assembly rotationally mounted to the base, the main shaft assembly including a main shaft, an end effector supported by the main shaft, and a first end effector drive shaft drivingly coupled to the end effector; a main shaft drive rotationally driving the main shaft relative to the base: a first input drive shaft transmitting a first input torque; and a first transmission having a first input link rotationally coupled to the first input drive shaft, a first output link rotationally coupled with the first end effector drive shaft, and a first base link, the first transmission providing a first gear ratio between the first input link and the first output link so as to transmit a first output torque to the main shaft assembly in response to the first input torque, a first end effector torque being transmitted by the first end effector drive shaft to the end effector in response to the first output torque, the first base link rotationally coupled with the main shaft by a second gear ratio such that the first base link, in response to the first input torque, transmits a first counteracting torque to the main shaft that is opposite in direction from the first output torque such that the first counteracting torque inhibits rotational driving of the main shaft assembly by the first output torque. a base; a main shaft assembly rotationally mounted to the base, the main shaft assembly including a main shaft, an end effector supported by the main shaft, and a first end effector drive shaft drivingly coupled to the end effector; a main shaft drive rotationally driving the main shaft relative to the base: a first input drive shaft transmitting a first input torque; and a first transmission having a first input link rotationally coupled to the first input drive shaft, a first output link rotationally coupled with the first end effector drive shaft, and a first base link, the first transmission providing a first gear ratio between the first input link and the first output link so as to transmit a first output torque to the main shaft assembly in response to the first input torque, a first end effector torque being transmitted by the first end effector drive shaft to the end effector in response to the first output torque, the first base link rotationally coupled with the main shaft by a second gear ratio such that the first base link, in response to the first input torque, transmits a first counteracting torque to the main shaft that is opposite in direction from the first output torque such that the first counteracting torque inhibits rotational driving of the main shaft assembly by the first output torque.
A composition comprising: a multi-stage flexible acrylic resin; and a branched polymer which is a reaction product of reactants comprising one or more monoethylenically unsaturated ester monomers, a chain transfer agent in an amount of 0.1 to 10 weight percent, and a crosslinker in an amount of 0.1 to 10 weight percent of a crosslinker, wherein weight percent is based on total amount of reactants, provided the amount of crosslinker in moles is less than the amount of chain transfer agent in moles; wherein said branched polymer is characterized by a polymer branching ratio, g', of less than 1; and wherein g ′ = η branched η linear M measured by gel permeation chromatography with online multi-angle light scattering (MALS) detector, viscometer, and differential refractive index (dRI) detector. a multi-stage flexible acrylic resin; and a branched polymer which is a reaction product of reactants comprising one or more monoethylenically unsaturated ester monomers, a chain transfer agent in an amount of 0.1 to 10 weight percent, and a crosslinker in an amount of 0.1 to 10 weight percent of a crosslinker, wherein weight percent is based on total amount of reactants, provided the amount of crosslinker in moles is less than the amount of chain transfer agent in moles; wherein said branched polymer is characterized by a polymer branching ratio, g', of less than 1; and wherein g ′ = η branched η linear M measured by gel permeation chromatography with online multi-angle light scattering (MALS) detector, viscometer, and differential refractive index (dRI) detector.
A contact lens dispensing container for direct application of a contact lens onto a wearer's eye comprising: an upwardly opening receptacle configured to receive a single contact lens and storage solution, the container having a peripheral flange providing a planar engagement surface surrounding the receptacle, characterized in that it further comprises: a peelable cover sheet securable to the engagement surface to seal the container and peelable from the engagement surface to allow removal of the content lens in use; an applicator comprising a handle, having first and second ends, the handle being pivotably mounted on the flange and having a carrier located at the first end of the handle and a hand grip located at the second end of the handle; the applicator being moveable between stowed and deployed positions, wherein in the stowed position the carrier is received in the receptacle with the handle not extending above the engagement surface, and in the deployed position the applicator is rotated from the stowed position so that the carrier is located above the engagement surface to facilitate direct application of a contact lens by the carrier onto a wearer's eye without need for manual contact. an upwardly opening receptacle configured to receive a single contact lens and storage solution, the container having a peripheral flange providing a planar engagement surface surrounding the receptacle, characterized in that it further comprises: a peelable cover sheet securable to the engagement surface to seal the container and peelable from the engagement surface to allow removal of the content lens in use; an applicator comprising a handle, having first and second ends, the handle being pivotably mounted on the flange and having a carrier located at the first end of the handle and a hand grip located at the second end of the handle; the applicator being moveable between stowed and deployed positions, wherein in the stowed position the carrier is received in the receptacle with the handle not extending above the engagement surface, and in the deployed position the applicator is rotated from the stowed position so that the carrier is located above the engagement surface to facilitate direct application of a contact lens by the carrier onto a wearer's eye without need for manual contact. a peelable cover sheet securable to the engagement surface to seal the container and peelable from the engagement surface to allow removal of the content lens in use; an applicator comprising a handle, having first and second ends, the handle being pivotably mounted on the flange and having a carrier located at the first end of the handle and a hand grip located at the second end of the handle; the applicator being moveable between stowed and deployed positions, wherein in the stowed position the carrier is received in the receptacle with the handle not extending above the engagement surface, and in the deployed position the applicator is rotated from the stowed position so that the carrier is located above the engagement surface to facilitate direct application of a contact lens by the carrier onto a wearer's eye without need for manual contact.
An optical device comprising: a plurality of first reflecting surfaces that are separated from each other in a direction along a first axis disposed so as to reflect parts of first light to an arc-shaped first region surrounding the first axis, the first light having a light distribution with an optical axis parallel to the first axis; and a second reflecting surface and a third reflecting surface that are disposed such that the second reflecting surface and the third reflecting surface meet each other on the first axis, and such that the plurality of first reflecting surfaces are disposed between the second reflecting surface and the third reflecting surface. a plurality of first reflecting surfaces that are separated from each other in a direction along a first axis disposed so as to reflect parts of first light to an arc-shaped first region surrounding the first axis, the first light having a light distribution with an optical axis parallel to the first axis; and a second reflecting surface and a third reflecting surface that are disposed such that the second reflecting surface and the third reflecting surface meet each other on the first axis, and such that the plurality of first reflecting surfaces are disposed between the second reflecting surface and the third reflecting surface.
An immunoconjugate comprising an antibody or antigen-binding fragment thereof covalently attached to a cytotoxic agent, wherein the antibody or antigen-binding fragment thereof is a monoclonal antibody or antigen-binding fragment thereof that binds to CD22 and comprises a heavy chain variable domain having the amino acid sequence of SEQ ID NO:16, and a light chain variable domain having the amino acid sequence of SEQ ID NO:18, and wherein the antibody or antigen-binding fragment thereof further comprises a cysteine at position 205 of the light chain according to Kabat numbering convention or position 118 of the heavy chain according to EU numbering convention.
Method for carrying out a process for amplification of nucleic acids, wherein sample nucleic acids (31; 51; 61; 71) and reference nucleic acids (32-35; 52-54; 62-64, 72-73) are amplified in separate reactions, wherein signals from the amplification are observed in real time and the number of amplification cycles and/or the duration of the amplification process are dynamically adjusted according to signals from the amplification, characterized in that the method is used for total genome amplification, wherein at least a first comparative sample having a defined concentration of nucleic acid of a reference genome is run at the same time and the amount of the reference genome used corresponds to the maximum usable amount of DNA for total genome amplification systems.
An apparatus for holding a product dispenser, comprising: a mounting collar having a peripheral flange and an opening defined by the peripheral flange, wherein the opening is configured to receive a container, and the mounting collar includes an upper surface for engaging the container and a lower surface for engaging a top of a mounting surface; and a locking arrangement, characterized in that the locking arrangement is supported by the mounting collar and rotationally operative to secure and compress the mounting collar to the mounting surface without tools, wherein the locking arrangement includes a screw having a threaded shaft with a first end and a second end, a nut at the first end, and a flap at the second end, and wherein rotation of the nut in a first direction causes the flap to travel along the threaded shaft toward the first end. a mounting collar having a peripheral flange and an opening defined by the peripheral flange, wherein the opening is configured to receive a container, and the mounting collar includes an upper surface for engaging the container and a lower surface for engaging a top of a mounting surface; and a locking arrangement, characterized in that the locking arrangement is supported by the mounting collar and rotationally operative to secure and compress the mounting collar to the mounting surface without tools, wherein the locking arrangement includes a screw having a threaded shaft with a first end and a second end, a nut at the first end, and a flap at the second end, and wherein rotation of the nut in a first direction causes the flap to travel along the threaded shaft toward the first end.
A non-glucocorticoidal compound which (a) is capable of binding to a T-cell adhesion molecule, and/or (b) is capable of blocking the binding site of a T-cell adhesion molecule, and which decreases or inhibits the binding of mammalian T-cells to mammalian endothelial cells, for use in a method of prophylaxis and/or treatment of neurological adverse events caused by the administration of a medicament which comprises re-directing of T-cells against target cells in a patient, wherein said medicament is a CD19 x CD3 bispecific single chain antibody, wherein the non-glucocorticoidal compound is to be administered prior to and concomitantly with (i) an initial dosing, (ii) a re-exposure; and/or (iii) an increase of said administration of a CD19 x CD3 bispecific single chain antibody, wherein said neurological adverse events are one or more of disorientation/confusion, word finding problems/aphasia, seizure, kinetic tremor, ataxia, dysarthria and handwriting problems, wherein said patient is a mammal. (a) is capable of binding to a T-cell adhesion molecule, and/or (b) is capable of blocking the binding site of a T-cell adhesion molecule,
A method of forming Mo-Si-B alloy powder comprising: preparing a mixture that includes Mo powder, Si 3 N 4 powder and BN powder; adding a polymer binder and liquid to the mixture to form a slurry; spray drying the slurry to form a spray dried powder containing Mo powder, Si 3 N 4 powder and BN powder particles; thermally treating the spray dried powder to remove the binder, alloy the powders of the spray dried powder, and remove carbon, nitrogen and oxygen atoms, wherein thermally treating the spray dried powder forms at least some partially sintered Mo-Si-B alloy powder pieces; milling the partially sintered Mo-Si-B alloy powder pieces in a milling container having contact surfaces composed of Mo-based material or lined and/or coated with Mo-based material to break down the pieces; and sieving the milled Mo-Si-B alloy powder pieces to reclaim the Mo-Si-B alloy powder, wherein milling the partially sintered Mo-Si-B alloy powder pieces comprises operation of a milling media composed of Mo-based material or lined and/or coated with Mo-based material that breaks down the pieces in the milling container. preparing a mixture that includes Mo powder, Si 3 N 4 powder and BN powder; adding a polymer binder and liquid to the mixture to form a slurry; spray drying the slurry to form a spray dried powder containing Mo powder, Si 3 N 4 powder and BN powder particles; thermally treating the spray dried powder to remove the binder, alloy the powders of the spray dried powder, and remove carbon, nitrogen and oxygen atoms, wherein thermally treating the spray dried powder forms at least some partially sintered Mo-Si-B alloy powder pieces; milling the partially sintered Mo-Si-B alloy powder pieces in a milling container having contact surfaces composed of Mo-based material or lined and/or coated with Mo-based material to break down the pieces; and sieving the milled Mo-Si-B alloy powder pieces to reclaim the Mo-Si-B alloy powder, wherein milling the partially sintered Mo-Si-B alloy powder pieces comprises operation of a milling media composed of Mo-based material or lined and/or coated with Mo-based material that breaks down the pieces in the milling container.
A coenzyme Q10 solubilizing composition in which coenzyme Q10 is encapsulated in a micelle comprising glycyrrhizic acid or a salt thereof, a bile acid or a salt thereof, and an unsaturated fatty acid, wherein the unsaturated fatty acid is eicosapentaenoic acid or docosahexaenoic acid.
A method for making a thermoplastic vulcanizate, the method comprising the steps of: (i) introducing an elastomer to an extrusion reactor, wherein the elastomer comprises less than 25 phr of extender oil; (ii) introducing a thermoplastic resin to the extrusion reactor; (iii) introducing at least 7 phr of an inert solid particulate to the extrusion reactor; (iv) introducing a first amount of process oil to the extrusion reactor at a first oil injection location; (v) introducing a second amount of process oil to the extrusion reactor at a second oil injection location, where the second oil injection location is downstream of the first oil injection location, and wherein the second amount of process oil is greater than the first amount of process oil; (vi) introducing a curative to the extrusion reactor a location that is downstream of the second oil injection location; (vii) introducing a third amount of process oil to the extrusion reactor at a third oil injection location, where the third oil injection location is downstream of the location where the curative is introduced to the extrusion reactor; and (viii) dynamically vulcanizing the elastomer with the curative in the presence of the thermoplastic resin to form the thermoplastic vulcanizate; wherein the total weight percent of oil in the thermoplastic vulcanizate is greater than 25 wt% based on the weight of the thermoplastic vulcanizate; and wherein the amount of process oil injected at the first and second oil injection locations comprises at least 30 wt% of the total weight of the process oil introduced to the extrusion reactor; characterised in that, the extrusion reactor operates at an extrusion rate of from 50 kg/hr to 120 kg/hr. (i) introducing an elastomer to an extrusion reactor, wherein the elastomer comprises less than 25 phr of extender oil; (ii) introducing a thermoplastic resin to the extrusion reactor; (iii) introducing at least 7 phr of an inert solid particulate to the extrusion reactor; (iv) introducing a first amount of process oil to the extrusion reactor at a first oil injection location; (v) introducing a second amount of process oil to the extrusion reactor at a second oil injection location, where the second oil injection location is downstream of the first oil injection location, and wherein the second amount of process oil is greater than the first amount of process oil; (vi) introducing a curative to the extrusion reactor a location that is downstream of the second oil injection location; (vii) introducing a third amount of process oil to the extrusion reactor at a third oil injection location, where the third oil injection location is downstream of the location where the curative is introduced to the extrusion reactor; and (viii) dynamically vulcanizing the elastomer with the curative in the presence of the thermoplastic resin to form the thermoplastic vulcanizate;
Access device to the upper part of a vehicle type of tank truck, the device comprising: - a frame, - an access platform, - a ladder comprising two uprights (10, 11) and a set of bars, said ladder at its upper end carrying said access platform, and at its lower end being linked to the frame, - a support structure of said ladder relative to the frame, characterized in that the connection between the ladder and the frame is at least one articulation providing a pivot connection along an axis parallel to the bars of the ladder, and in that said ladder can tilt relative to the frame between a first inclined position called "working position" and a second position corresponding to the vertical position called "rest position" or vice versa. - a frame, - an access platform, - a ladder comprising two uprights (10, 11) and a set of bars, said ladder at its upper end carrying said access platform, and at its lower end being linked to the frame, - a support structure of said ladder relative to the frame, characterized in that the connection between the ladder and the frame is at least one articulation providing a pivot connection along an axis parallel to the bars of the ladder,
Device for compressing gaseous fluid, comprising: - an inlet for gaseous fluid to be compressed and an outlet for compressed gaseous fluid, - a cylindrical main enclosure containing gaseous fluid, - at least one first chamber, thermally coupled to a heat source adapted for adding heat energy to the gaseous fluid, - at least one second chamber, thermally coupled to a cold source in order to transfer heat energy from the gaseous fluid to the cold source, - at least one piston assembly mounted in a cylindrical sleeve so as to move in an axial direction and separating the first chamber and second chamber inside said main enclosure, - at least one regenerative heat exchanger arranged circumferentially around the sleeve and establishing a fluid communication between the first and second chambers by means of at least one first communication line, the first chamber comprising at least one first communication passage arranged at a first end of the enclosure and connected to the first communication line, the second chamber comprising at least one second communication passage arranged at a second end of the enclosure and connected to the first communication line, the first chamber, the second chamber, and the first communication line forming a first compression stage, characterised in that the device comprises a plurality of third and fourth passages in the form of ports arranged in an intermediate portion of the enclosure between the first and second ends, the plurality of third and fourth passages being prearranged for the fluid connection of third and fourth chambers (E21,E22) which are possibly arranged in the main enclosure between the first and second chambers. - an inlet for gaseous fluid to be compressed and an outlet for compressed gaseous fluid, - a cylindrical main enclosure containing gaseous fluid, - at least one first chamber, thermally coupled to a heat source adapted for adding heat energy to the gaseous fluid, - at least one second chamber, thermally coupled to a cold source in order to transfer heat energy from the gaseous fluid to the cold source, - at least one piston assembly mounted in a cylindrical sleeve so as to move in an axial direction and separating the first chamber and second chamber inside said main enclosure, - at least one regenerative heat exchanger arranged circumferentially around the sleeve and establishing a fluid communication between the first and second chambers by means of at least one first communication line,
An aerosol composition, comprising a) a cosmetic styling agent, containing a1) glycerol a2) carboxylic acid group-containing polymer, 100 wt.% of the carboxylic acid group-containing polymer being a copolymer formed from the monomers a2i) N-tert-octylacrylamide a2ii) acrylic acid a2iii) tert-butylaminoethyl methacrylic acid and possibly other monomers, characterized in that the ratio of the proportions by weight of component a1) and component a2) in the cosmetic styling agent is between 2:1 and 10:1, b) a propellant or propellant mixture. a) a cosmetic styling agent, containing a1) glycerol a2) carboxylic acid group-containing polymer, 100 wt.% of the carboxylic acid group-containing polymer being a copolymer formed from the monomers a2i) N-tert-octylacrylamide a2ii) acrylic acid a2iii) tert-butylaminoethyl methacrylic acid and possibly other monomers, characterized in that the ratio of the proportions by weight of component a1) and component a2) in the cosmetic styling agent is between 2:1 and 10:1, a1) glycerol a2) carboxylic acid group-containing polymer, 100 wt.% of the carboxylic acid group-containing polymer being a copolymer formed from the monomers a2i) N-tert-octylacrylamide a2ii) acrylic acid a2iii) tert-butylaminoethyl methacrylic acid and possibly other monomers, a2i) N-tert-octylacrylamide a2ii) acrylic acid a2iii) tert-butylaminoethyl methacrylic acid and possibly other monomers, b) a propellant or propellant mixture.