mhurhangee/ep-ind-claims huggingface dataset:
Dispensing device for receiving and dispensing a foodstuff to a dispenser device with a receiving container which has a circumferential container wall for delimitation of a receiving space, an outlet opening connected to the receiving space for connection to a suction connection of the dispenser device, a floating lid which can be displaced over the receiving space, which has a venting apparatus, which in turn has an adjusting element which can be adjusted relative to a lid base body between a closed position, in which it closes a venting opening, and a venting position, in which it at least partially opens the venting opening, characterized in that the adjusting element is held on the lid base body via a screw connection and can be rotated between the closed position and the venting position via a handle formed by a grab handle of the floating lid. an outlet opening connected to the receiving space for connection to a suction connection of the dispenser device, a floating lid which can be displaced over the receiving space, which has a venting apparatus, which in turn has an adjusting element which can be adjusted relative to a lid base body between a closed position, in which it closes a venting opening, and a venting position, in which it at least partially opens the venting opening, characterized in that the adjusting element is held on the lid base body via a screw connection and can be rotated between the closed position and the venting position via a handle formed by a grab handle of the floating lid.
Use of at least one metal organosilicate polymer compound in the form of particles having formula II below: Formula II: R 8 Si 8 M 6 O 1e y, in which: - R is selected from the group comprising a linear or branched, substituted or non-substituted alkyl group, a linear or branched, substituted or non-substituted alkenyl group, a substituted or non-substituted aryl group and a substituted or non-substituted benzyl group, - y ≥ 4, - M is selected from the group comprising calcium, magnesium, zinc, strontium and mixtures thereof, and - the molar ratio Si/M is between 1.8 and 1.3 inclusive, for the protection against the oxidation and/or electromagnetic radiation of a compound sensitive to oxidation and/or electromagnetic radiation. - R is selected from the group comprising a linear or branched, substituted or non-substituted alkyl group, a linear or branched, substituted or non-substituted alkenyl group, a substituted or non-substituted aryl group and a substituted or non-substituted benzyl group, - y ≥ 4, - M is selected from the group comprising calcium, magnesium, zinc, strontium and mixtures thereof, and - the molar ratio Si/M is between 1.8 and 1.3 inclusive,
A ventilation mask comprising: a mask body having a first opening, and a sealing member configured to engage a face of a patient so as to surround at least a mouth and/or a nose of the patient; a frame connected to an outer surface of the mask body and having an interface member configured to interlock with the mask body at the first opening; and an elbow having a first end connectable with a gas supply, and a second end configured to be fixedly secured to the interface member of the frame and to enable flow of gas from the elbow into the mask body through the first opening, characterized in that the mask body comprises a grooved portion disposed around the first opening, and the interface member comprises a protruding flange configured so as to be press-fit within the grooved portion to interlock and seal the interface member with the mask body, wherein the second end of the elbow has a flange configured to hold the grooved portion of the mask body against the protruding flange of the interface member. a mask body having a first opening, and a sealing member configured to engage a face of a patient so as to surround at least a mouth and/or a nose of the patient; a frame connected to an outer surface of the mask body and having an interface member configured to interlock with the mask body at the first opening; and an elbow having a first end connectable with a gas supply, and a second end configured to be fixedly secured to the interface member of the frame and to enable flow of gas from the elbow into the mask body through the first opening, characterized in that the mask body comprises a grooved portion disposed around the first opening, and the interface member comprises a protruding flange configured so as to be press-fit within the grooved portion to interlock and seal the interface member with the mask body, wherein the second end of the elbow has a flange configured to hold the grooved portion of the mask body against the protruding flange of the interface member.
A method for the production of a component having at least one element (27, 2, 22, 15) arranged in the component, specifically at least one conduit arranged in an aerodynamically contoured rib, a conduit part, or a support element, wherein the component has an element passage through which the at least one element (27, 2, 22, 15) passes, wherein the method comprises the following steps: constructing the component, with the element passage, together with the at least one element (27, 2, 22, 15), in layers by means of a generative production process, and forming the at least one element (27, 2, 22, 15) on both ends of the same with a connector segment (3, 4; 23, 24) and/or a fastening flange (18, 19), wherein the connector segment (3, 4) and/or the fastening flange (18, 19) has/have a larger cross-section or a great diameter than the element passage of the component.
Compound of the formula: wherein R 1, R 2, R 3, R 4, R 5, R 6, R 7, R 8, R 9 R 10, R 11, R 12, R 13, R 14, R 15, R 16, R 17, R 18 are selected from: -H, -(C 1 -C 12)-alkyl, -O- (C 1 -C 12) -alkyl, halogen, -NH 2, -NO 2; wherein at least one of the radicals R 10, R 12, R 15, R 17 is other than -H. R 1, R 2, R 3, R 4, R 5, R 6, R 7, R 8, R 9 R 10, R 11, R 12, R 13, R 14, R 15, R 16, R 17, R 18 are selected from: -H, -(C 1 -C 12)-alkyl, -O- (C 1 -C 12) -alkyl, halogen, -NH 2, -NO 2; wherein at least one of the radicals R 10, R 12, R 15, R 17 is other than -H.
A method performed by a base station in a wireless communication system, the method comprising: transmitting, to a user equipment, UE, a first message comprising information on at least one bandwidth part, BWP, including first configuration information on a Physical Downlink Control Channel, PDCCH, and second configuration information on a Physical Downlink Shared Control Channel, PDSCH, via Radio Resource Control, RRC, the method being characterized by: transmitting, to the UE, a second message comprising downlink control information, DCI, to be used for BWP activation and including resource allocation information for the scheduling of the PDSCH, wherein resource blocks, RBs, for data transmission from the UE to the base station within the BWP, are identified by the resource allocation information, and wherein the at least one bandwidth part is associated with a subcarrier spacing and a cyclic prefix, CP, length, according to which the PDCCH and PDSCH are indicated in the first message. transmitting, to a user equipment, UE, a first message comprising information on at least one bandwidth part, BWP, including first configuration information on a Physical Downlink Control Channel, PDCCH, and second configuration information on a Physical Downlink Shared Control Channel, PDSCH, via Radio Resource Control, RRC, the method being characterized by: transmitting, to the UE, a second message comprising downlink control information, DCI, to be used for BWP activation and including resource allocation information for the scheduling of the PDSCH, wherein resource blocks, RBs, for data transmission from the UE to the base station within the BWP, are identified by the resource allocation information, and wherein the at least one bandwidth part is associated with a subcarrier spacing and a cyclic prefix, CP, length, according to which the PDCCH and PDSCH are indicated in the first message.
An aqueous pharmaceutical formulation comprising: (a) an isolated anti-Aβ protofibril antibody that binds to human Aβ protofibrils, at a concentration of 80 mg/mL to 300 mg/mL, (b) 100 mM to 400 mM arginine, (c) 0.01% w/v to 0.1% w/v polysorbate 80, and (d) a pharmaceutically acceptable buffer, wherein the pharmaceutical formulation has a pH ranging from 4.5 to 5.5, wherein the isolated anti-Aβ protofibril antibody is lecanemab, and wherein the arginine is arginine, arginine hydrochloride, or a combination thereof. (a) an isolated anti-Aβ protofibril antibody that binds to human Aβ protofibrils, at a concentration of 80 mg/mL to 300 mg/mL, (b) 100 mM to 400 mM arginine, (c) 0.01% w/v to 0.1% w/v polysorbate 80, and (d) a pharmaceutically acceptable buffer, wherein the pharmaceutical formulation has a pH ranging from 4.5 to 5.5, wherein the isolated anti-Aβ protofibril antibody is lecanemab, and wherein the arginine is arginine, arginine hydrochloride, or a combination thereof.
A method for producing at least two antibodies that bind to a selected antigen or epitope of interest, said method comprises at least the following steps: a) providing a population of B cells expressing a limited VL repertoire comprising no more than 10 different VL regions, wherein essentially all of said B cells carry at least one VL, wherein said population of B cells is obtained from a transgenic non-human animal carrying a limited VL repertoire, wherein said limited VL repertoire consists of less than 10 VL, wherein said non-human animal has been immunized with said antigen, and wherein said population of B cells comprises B cells obtained from spleen and/or at least one lymph node, b) obtaining nucleic acids from said B cells, c) optionally, amplification of nucleic acid sequences encoding immunoglobulin heavy chain variable regions in said sample, d) at least partial sequencing of essentially all obtained nucleic acids of step b) or the amplification products of step c), e) performing a frequency analysis of VH sequences from step d), comprising heavy chain CDR3 sequences, f) selecting the 20 most abundant VH sequences, g) providing host cells with at least one vector comprising at least one of said VH sequences and at least one VL sequence of said limited VL repertoire, h) culturing said host cells and allowing for expression of VH and VL polypeptides, i) obtaining said antibodies. a) providing a population of B cells expressing a limited VL repertoire comprising no more than 10 different VL regions, wherein essentially all of said B cells carry at least one VL, wherein said population of B cells is obtained from a transgenic non-human animal carrying a limited VL repertoire, wherein said limited VL repertoire consists of less than 10 VL, wherein said non-human animal has been immunized with said antigen, and wherein said population of B cells comprises B cells obtained from spleen and/or at least one lymph node, b) obtaining nucleic acids from said B cells, c) optionally, amplification of nucleic acid sequences encoding immunoglobulin heavy chain variable regions in said sample, d) at least partial sequencing of essentially all obtained nucleic acids of step b) or the amplification products of step c), e) performing a frequency analysis of VH sequences from step d), comprising heavy chain CDR3 sequences, f) selecting the 20 most abundant VH sequences, g) providing host cells with at least one vector comprising at least one of said VH sequences and at least one VL sequence of said limited VL repertoire, h) culturing said host cells and allowing for expression of VH and VL polypeptides, i) obtaining said antibodies.
Side lift spreader for handling empty containers, comprising a main carriage which is connectable to a lifting device to be movable along a mast of the lifting device, a main frame which is arranged to the main carriage, and at least one container support which is arranged to the main frame, characterized in that the side lift spreader comprises at least one tilt cylinder (30, 31) for moving said container support with respect to the main carriage to tilt the container.
A method of changing the shape of a liquid droplet in an external liquid wherein the liquid droplet has an aspect ratio and the shape change is defined as at least a 10% increase or decrease in the aspect ratio in at least one orientation, and preferably wherein said external liquid is a consumer goods product, wherein the droplet comprises; (a) a liquid, preferably wherein said liquid is an aqueous liquid or an oil, more preferably an oil, and even more preferably wherein the oil is selected from the group consisting of alkanes, tri- and di- and monoglycerides, silicone oils, mineral oils, and mixtures thereof; (b) an internal solid material, the internal solid material defining the shape of the droplet; preferably wherein said internal solid material is selected from waxes, preferably microcrystalline waxes, paraffins, beeswax, ozokerite, and alkylated silicone waxes; polymeric materials, preferably cellulose, polydimethylsiloxane, and biopolymers, more preferably gums, and still more preferably gums such as gellan, xanthan, and carrageenan; inorganic materials, even more preferably zinc oxide and zinc pyrithione; and mixtures thereof; and (c) a benefit agent; preferably wherein said benefit agent is selected from compounds useful in cleaning compositions, more preferably fabric or household cleaning compositions or body wash and body care compositions, and mixtures thereof; wherein the three-phase contact angle of the liquid on the internal solid material is less than 1°; the liquid droplet has a yield stress of between 100 Pascals and 1,000,000 Pascals, preferably between 1000 Pascals and 10,000 Pascals, when measured at 25 °C; and wherein the liquid droplet has an interfacial tension with the external liquid, and the solid material exerts a yield stress which matches or exceeds the pressure exerted by the interfacial tension; comprising the step of: changing the interfacial tension, or changing the yield stress, or a combination of both. (a) a liquid, preferably wherein said liquid is an aqueous liquid or an oil, more preferably an oil, and even more preferably wherein the oil is selected from the group consisting of alkanes, tri- and di- and monoglycerides, silicone oils, mineral oils, and mixtures thereof; (b) an internal solid material, the internal solid material defining the shape of the droplet; preferably wherein said internal solid material is selected from waxes, preferably microcrystalline waxes, paraffins, beeswax, ozokerite, and alkylated silicone waxes; polymeric materials, preferably cellulose, polydimethylsiloxane, and biopolymers, more preferably gums, and still more preferably gums such as gellan, xanthan, and carrageenan; inorganic materials, even more preferably zinc oxide and zinc pyrithione; and mixtures thereof; and (c) a benefit agent; preferably wherein said benefit agent is selected from compounds useful in cleaning compositions, more preferably fabric or household cleaning compositions or body wash and body care compositions, and mixtures thereof;
A biomedical signal acquisition system comprising an AC coupled differential input instrumentation amplifier and a capacitor circuit directly connected to one of two input lines (inp, inn) of the instrumentation amplifier respectively, characterized in that the capacitor circuit is a variable capacitor circuit comprising a plurality of MOS capacitors, each MOS capacitor being implemented by a MOS transistor with the gate terminal connected to the respective input line (inp, inn) of the instrumentation amplifier and with the drain terminal shorted with the source terminal and connected to a control voltage signal (Vc), said MOS capacitors being connected in parallel through the gate terminal, and wherein the control voltage signal (Vc) is a variable voltage; said MOS capacitors configured to be operated in a cut-off region in which the equivalent capacitance of each MOS capacitor remains constant for variations of the first voltage signal; and wherein the variable capacitor circuits are configured to be tuned in capacitance value to reduce the capacitance mismatch between the input lines (inp, inn).
A composition comprising: (i) an antibody or an antigen-binding fragment thereof with binding specificity for ICAM-1, wherein the antibody or antigen-binding fragment thereof comprises the following amino acid sequences: FSNAWMSWVRQAPG and AFIWYDGSNKYYADSVKGR and ARYSGWYFDY and CTGSSSNIGAGYDVH and DNNNRPS and CQSYDSSLSAWL; (ii) a further anticancer agent selected from IMiDs and bortezomib; and (iii) a pharmaceutically acceptable excipient, diluent or carrier. FSNAWMSWVRQAPG and AFIWYDGSNKYYADSVKGR and ARYSGWYFDY and CTGSSSNIGAGYDVH and DNNNRPS and CQSYDSSLSAWL; (ii) a further anticancer agent selected from IMiDs and bortezomib; and (iii) a pharmaceutically acceptable excipient, diluent or carrier.
A method of manufacturing a sensor package comprising the steps of: providing a plurality of sensing devices; providing a silicon carrier substrate comprising a plurality of recesses formed in a first side; placing each sensing device within a respective one of the plurality of recesses; providing a glass substrate having a plurality of apertures formed therethrough; orientating the glass substrate over the silicon carrier substrate to align the plurality of apertures with the plurality of sensing devices arranged in the plurality of recesses of the silicon carrier substrate; providing a voltage source for applying a voltage across the silicon carrier substrate and the glass substrate, the voltage source comprising a first electrode and a second electrode; and applying a voltage across the silicon carrier substrate and the glass substrate to anodically bond the sensing devices to the glass substrate. providing a plurality of sensing devices; providing a silicon carrier substrate comprising a plurality of recesses formed in a first side; placing each sensing device within a respective one of the plurality of recesses; providing a glass substrate having a plurality of apertures formed therethrough; orientating the glass substrate over the silicon carrier substrate to align the plurality of apertures with the plurality of sensing devices arranged in the plurality of recesses of the silicon carrier substrate; providing a voltage source for applying a voltage across the silicon carrier substrate and the glass substrate, the voltage source comprising a first electrode and a second electrode; and applying a voltage across the silicon carrier substrate and the glass substrate to anodically bond the sensing devices to the glass substrate.
Vehicle comprising: - a body, - a door assembly comprising a door hingely connected to the body by at least one first hinge, a door frame, and a horizontally extending first guide unit; and - a retractable stair assembly comprising: a stairway comprising a plurality of steps, wherein the stairway is configured to be horizontally retractable between a first position, in which the stairway is provided inside the body in an inverted upside-down orientation and a second position, in which the stairway is provided at least partly outside the body and still in the inverted upside-down orientation, a hand rail coupled on a first end to the first guide unit and on a second end opposing to the first end coupled to the stairway, the first end being provided moveable along the first guide unit, a second hinge provided to rotate the stairway in said second position from the inverted upside-down orientation to a third position in which the stairway is in the regular orientation. - a body, - a door assembly comprising a door hingely connected to the body by at least one first hinge, a door frame, and a horizontally extending first guide unit; and a door hingely connected to the body by at least one first hinge, a door frame, and a horizontally extending first guide unit; and - a retractable stair assembly comprising: a stairway comprising a plurality of steps, wherein the stairway is configured to be horizontally retractable between a first position, in which the stairway is provided inside the body in an inverted upside-down orientation and a second position, in which the stairway is provided at least partly outside the body and still in the inverted upside-down orientation, a hand rail coupled on a first end to the first guide unit and on a second end opposing to the first end coupled to the stairway, the first end being provided moveable along the first guide unit, a second hinge provided to rotate the stairway in said second position from the inverted upside-down orientation to a third position in which the stairway is in the regular orientation. a stairway comprising a plurality of steps, wherein the stairway is configured to be horizontally retractable between a first position, in which the stairway is provided inside the body in an inverted upside-down orientation and a second position, in which the stairway is provided at least partly outside the body and still in the inverted upside-down orientation, a hand rail coupled on a first end to the first guide unit and on a second end opposing to the first end coupled to the stairway, the first end being provided moveable along the first guide unit, a second hinge provided to rotate the stairway in said second position from the inverted upside-down orientation to a third position in which the stairway is in the regular orientation.
An antistatic agent, comprising at least one polymer compound which is obtained by a reaction of a polyester (a) obtained by a reaction between a diol and a dicarboxylic acid, a compound (b) comprising at least one ethyleneoxy group and having hydroxy groups at both ends, and an epoxy compound comprising two or more epoxy groups, wherein the diol is at least either of 1,4-butanediol and ethylene glycol, and the dicarboxylic acid is succinic acid or a dicarboxylic acid mixture comprising succinic acid. the diol is at least either of 1,4-butanediol and ethylene glycol, and the dicarboxylic acid is succinic acid or a dicarboxylic acid mixture comprising succinic acid.
A method for manufacturing a cellulose nanofiber, characterized by comprising the step of fibrillating cellulose in a polyester based resin, wherein the ester group concentration of the polyester based resin is 6.0 mmol/g or more and the terminal acid value is 10 KOH mg/g or more or the terminal hydroxyl value is 10 KOH mg/g or more, wherein ester group concentration (mmol/g) = amount of generation of ester group (mol)/[amount of charge of monomer (wt) - amount of generation of water (wt)] x 1000, wherein the amount of generation of ester group and the amount of generation of water is calculated on the assumption that the total amount of charged monomer undergoes an esterification reaction.
Method of thermal management of a building, on the basis of a thermal system equipped with a low-power generator, characterized in that it comprises a step of turning on the generator ahead of time in the absence of any occupant in the building so as to comply with a future comfort setpoint at a future instant, by taking account of the energy available (E generator_H) at the generator up until this future instant and of the energy necessary (E heating_H) to reach the future comfort setpoint within the building at this future instant.