mhurhangee/ep-ind-claims huggingface dataset:
A method of forming an engineered tissue construct, the method comprising: combining provided undifferentiated and/or substantially differentiated progenitor cells with a plurality of the nanoparticles and/or microparticles either formed from a biocompatible and biodegradable polymer selected from the group consisting of collagen, fibrin, gelatin, glycosaminoglycans, poly (hyaluronic acid), poly(sodium alginate), alginate, hyaluronan, agarose, poly(lactide)s, poly(glycolide)s, poly(lactide-co-glycolide)s, poly(lactic acid)s, poly(glycolic acid)s, poly(lactic acid-co-glycolic acid)s, polycaprolactone, polycarbonates, polyesteramides, polyanhydrides, poly(amino acids), polyorthoesters, polyacetyls, polycyanoacrylates, polyetheresters, poly(dioxanone)s, poly(alkylene alkylate)s, copolymers of polyethylene glycol and poly(lactide)s or poly(lactide-co-glycolide)s, biodegradable polyurethanes, and blends and/or copolymers thereof, or from calcium phosphate material, said plurality of nanoparticles and/or microparticles include at least one bioactive agent so that the nanoparticles and/or microparticles are dispersed and suspended with the undifferentiated and/or substantially differentiated progenitor cells in a culture medium; and culturing the suspension of nanoparticles and/or microparticles and undifferentiated and/or substantially differentiated progenitor cells in a well having a defined shape to form a self-assembled cell aggregate, the shape of the self-assembled cell aggregate being defined by surfaces of the well, wherein the undifferentiated and/or substantially differentiated progenitor cells comprise a population of chondrogenic cells and the chondrogenic cells endogenously produce an extracellular matrix when the population of chondrogenic cells is cultured in the annular well, and wherein the nanoparticles and/or microparticles include the at least one bioactive agent that is differentially and/or controllably released by the nanoparticles and/or HLZ:DPF microparticles, wherein the bioactive agent is selected from the group consisting of epidermal growth factor, hepatocyte growth factor, vascular endothelial growth factors (VEGF), fibroblast growth factors (bFGF), platelet-derived growth factors (PDGF), insulin-like growth factor, transforming growth factors, parathyroid hormone, parathyroid hormone related peptide, bone morphogenic proteins, transcription factors, growth differentiation factors, recombinant human growth factors and cartilage-derived morphogenic factors.
A curable composition comprising as essential components: an acrylic-modified alkyd resin comprising a copolymer comprising as essential components: an alkyd resin having an unsaturated bond in a molecular structure; and a polymerizable monomer having an unsaturated bond in a molecular structure, and a (meth)acrylate compound wherein the polymerizable monomer comprises an aromatic vinyl monomer as an essential component, and the mass ratio [ /] of the alkyd resin to the polymerizable monomer is 50/50 to 90/10. an acrylic-modified alkyd resin comprising a copolymer comprising as essential components: an alkyd resin having an unsaturated bond in a molecular structure; and a polymerizable monomer having an unsaturated bond in a molecular structure, and a (meth)acrylate compound wherein the polymerizable monomer comprises an aromatic vinyl monomer as an essential component, and the mass ratio [ /] of the alkyd resin to the polymerizable monomer is 50/50 to 90/10.
A computer-implemented method of generating a model for generating a synthetic electrocardiography, ECG, signal, said method comprising: receiving subject-specific training data for machine learning, said training data comprising a photoplethysmography, PPG, signal acquired from the subject and an ECG signal acquired from the subject, wherein the ECG signal provides a ground truth of the subject for associating the ECG signal with the PPG signal; using associated pairs of a time-series of the PPG signal and a corresponding time-series of the ECG signal as input to a deep neural network, DNN; and determining (106; 310), through the DNN, a subject-specific model relating the PPG signal of the subject to the ECG signal of the subject for converting the PPG signal to a synthetic ECG signal using the subject-specific model. receiving subject-specific training data for machine learning, said training data comprising a photoplethysmography, PPG, signal acquired from the subject and an ECG signal acquired from the subject, wherein the ECG signal provides a ground truth of the subject for associating the ECG signal with the PPG signal; using associated pairs of a time-series of the PPG signal and a corresponding time-series of the ECG signal as input to a deep neural network, DNN; and determining (106; 310), through the DNN, a subject-specific model relating the PPG signal of the subject to the ECG signal of the subject for converting the PPG signal to a synthetic ECG signal using the subject-specific model.
A fingerprint detecting circuit, applied in a fingerprint identification system transmitting a first signal to a finger, the fingerprint detecting circuit comprising: a conductive layer, configured to couple a touch from the finger; and an amplifier, comprising: a negative input terminal, coupled to the conductive layer; a positive input terminal, configured to receive a second signal; and an output terminal, wherein a first capacitance is formed between the output terminal and the negative input terminal; wherein a first phase of the first signal is inverse to a second phase of the second signal; wherein the first signal and the second signal drive the fingerprint detecting circuit to operation; wherein the second signal is expressed as: V 2 = − k ∗ V 1, wherein V1 represents the first signal, V2 represents the second signal, and k is a positive constant. a conductive layer, configured to couple a touch from the finger; and an amplifier, comprising: a negative input terminal, coupled to the conductive layer; a positive input terminal, configured to receive a second signal; and an output terminal, wherein a first capacitance is formed between the output terminal and the negative input terminal; a negative input terminal, coupled to the conductive layer; a positive input terminal, configured to receive a second signal; and an output terminal, wherein a first capacitance is formed between the output terminal and the negative input terminal; wherein a first phase of the first signal is inverse to a second phase of the second signal; wherein the first signal and the second signal drive the fingerprint detecting circuit to operation; wherein the second signal is expressed as: V 2 = − k ∗ V 1, wherein V1 represents the first signal, V2 represents the second signal, and k is a positive constant.
A device adapted to be worn by a user, comprising: an optical element adapted to be arranged in front of an eye of the user when the device is worn, the optical element being formed of a light-transmitting material allowing the user to see through the optical element, wherein the optical element is a lens; and a light source arranged on the optical element and adapted to illuminate at least a part of the eye of the user; and a sensor adapted to capture light which has been emitted from the light source and reflected on the eye; and a display that can be viewed by the user through the optical element; and wherein the sensor is arranged between the display and the optical element, and the sensor is arranged to view the eye through the optical element; characterized by the device further comprising: a light-reflecting material arranged to direct at least a part of the light emitted by the light source, wherein the light-reflecting material is arranged in a layer between the light source and the optical element. an optical element adapted to be arranged in front of an eye of the user when the device is worn, the optical element being formed of a light-transmitting material allowing the user to see through the optical element, wherein the optical element is a lens; and a light source arranged on the optical element and adapted to illuminate at least a part of the eye of the user; and a sensor adapted to capture light which has been emitted from the light source and reflected on the eye; and a display that can be viewed by the user through the optical element; and wherein the sensor is arranged between the display and the optical element, and the sensor is arranged to view the eye through the optical element;
A process for preparing a compound molindone comprising a step of reacting 2-methyl-3-ethyl-4-oxo-4,5,6,7-tetrahydroindole with bismorpholinomethane, wherein the amount of bismorpholinomethane is pre-charged at the initiation of the reaction or wherein the bismorpholinomethane is added in a stepwise manner with an initial amount charged at the start of the reaction, and further comprising at least one of the following steps: (a) removal of methylene-2-methyl-3-ethyl-4-oxo-4,5,6,7-tetrahydroindole by filtration under acidic conditions; (b) adsorbing oligomeric compounds on charcoal; (c) filtering and crystallizing molindone free base from a solvent. (a) removal of methylene-2-methyl-3-ethyl-4-oxo-4,5,6,7-tetrahydroindole by filtration under acidic conditions; (b) adsorbing oligomeric compounds on charcoal; (c) filtering and crystallizing molindone free base from a solvent.
An x-ray imager including a CMOS image sensor and a scintillator for converting x-rays to visible light the x-ray imager comprising: a first well of a first conductivity type formed in an epitaxial layer of a second conductivity type, wherein the second conductivity type is different to the first conductivity type, the first well and the epitaxial layer forming a photodiode configured to receive the visible light converted from the x-ray by the scintillator; a readout circuit configured to receive image information from the photodiode, the readout circuit being formed in a second well of the second conductivity type in the epitaxial layer, the first well arranged next to the second well, the first and second wells (226, 221) arranged at a surface of the epitaxial layer; and a first deep well of the first conductivity type extending below the second well under the readout circuit, wherein the epitaxial layer is configured to electrically isolate the first deep well from the first well and wherein the first deep well and the epitaxial layer are configured to form a diode to drain away parasitic electrons due to directly converted x-rays. a first well of a first conductivity type formed in an epitaxial layer of a second conductivity type, wherein the second conductivity type is different to the first conductivity type, the first well and the epitaxial layer forming a photodiode configured to receive the visible light converted from the x-ray by the scintillator; a readout circuit configured to receive image information from the photodiode, the readout circuit being formed in a second well of the second conductivity type in the epitaxial layer, the first well arranged next to the second well, the first and second wells (226, 221) arranged at a surface of the epitaxial layer; and a first deep well of the first conductivity type extending below the second well under the readout circuit, wherein the epitaxial layer is configured to electrically isolate the first deep well from the first well and wherein the first deep well and the epitaxial layer are configured to form a diode to drain away parasitic electrons due to directly converted x-rays.
A peripheral device for use with a host computing device, the peripheral device comprising: one or more compute elements; a security module configured to form a trusted execution environment on the peripheral device for processing sensitive data using sensitive code, wherein the sensitive data and sensitive code are provided by a trusted computing entity which is in communication with the host computing device; at least one encryption unit configured to encrypt and decrypt data transferred between the trusted execution environment and the trusted computing entity via the host computing device; wherein the security module is configured to compute and send an attestation to the trusted computing entity to attest that the sensitive code is in the trusted execution environment; characterized in that: the security module is configured to form the trusted execution environment by switching the peripheral device from a non-secure mode in which access to memory and registers of the peripheral via a linear address space is possible, into a secure mode in which access to specified memory and specified registers of the peripheral via the linear address space is disabled. one or more compute elements; a security module configured to form a trusted execution environment on the peripheral device for processing sensitive data using sensitive code, wherein the sensitive data and sensitive code are provided by a trusted computing entity which is in communication with the host computing device; at least one encryption unit configured to encrypt and decrypt data transferred between the trusted execution environment and the trusted computing entity via the host computing device; wherein the security module is configured to compute and send an attestation to the trusted computing entity to attest that the sensitive code is in the trusted execution environment; characterized in that: the security module is configured to form the trusted execution environment by switching the peripheral device from a non-secure mode in which access to memory and registers of the peripheral via a linear address space is possible, into a secure mode in which access to specified memory and specified registers of the peripheral via the linear address space is disabled.
An affinity peptide toward BMP-2 selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 14, SEQ ID NO: 15, SEQ ID NO: 16, SEQ ID NO: 17, SEQ ID NO: 18, SEQ ID NO: 19, SEQ ID NO: 20, SEQ ID NO: 21, SEQ ID NO: 22.
A component assembly suitable for use in living tissue comprising: a stainless steel part; a titanium part; and a filler material comprising at least one nickel foil layer and at least one titanium foil layer for bonding said stainless steel part to said titanium part. a stainless steel part; a titanium part; and a filler material comprising at least one nickel foil layer and at least one titanium foil layer for bonding said stainless steel part to said titanium part.
A method of preparing a positive electrode active material precursor, the method comprising: a first step of adding deionized water, an ammonium ion-containing solution, a basic aqueous solution and a metal additive including at least one element selected from the group consisting of Group 5 elements and Group 6 elements to a reactor and purging the reactor with nitrogen, wherein the metal additive is added in an amount such that the concentration of the additive in an initial reaction solution is in a range of 0.0005 M to 0.01 M; and a subsequent second step of adding a transition metal aqueous solution including a nickel raw material, a cobalt raw material, and a manganese raw material, an ammonium ion-containing solution, and a basic aqueous solution to the reactor and performing a co-precipitation reaction to prepare a positive electrode active material precursor having an average particle diameter (D 50) of 3 μm to 5 μm. a first step of adding deionized water, an ammonium ion-containing solution, a basic aqueous solution and a metal additive including at least one element selected from the group consisting of Group 5 elements and Group 6 elements to a reactor and purging the reactor with nitrogen, wherein the metal additive is added in an amount such that the concentration of the additive in an initial reaction solution is in a range of 0.0005 M to 0.01 M; and a subsequent second step of adding a transition metal aqueous solution including a nickel raw material, a cobalt raw material, and a manganese raw material, an ammonium ion-containing solution, and a basic aqueous solution to the reactor and performing a co-precipitation reaction to prepare a positive electrode active material precursor having an average particle diameter (D 50) of 3 μm to 5 μm.
Trailer coupling for a motor vehicle, with a coupling arm for coupling-on a trailer or a rear load carrier, wherein the coupling arm is mounted on a vehicle mounting (20; 420; 220), attachable to the motor vehicle with the aid of a bearing provided on the vehicle mounting (20; 420; 220), between a position of use provided for the attachment of the trailer or the rear load carrier and an inoperative position shifted closer to the motor vehicle, wherein there is fixed immovably to a vehicle mounting part (21; 421; 221) of the vehicle mounting (20; 420; 220) provided for attachment to the motor vehicle a bearing base body of the bearing on which is movably mounted at least one bearing element (32; 432, 232) carrying the coupling arm, wherein the trailer coupling has a fixing device for immovable fixing of the coupling arm in the position of use and/or the inoperative position, wherein the fixing device has at least one fixing element, which may be moved by adjustment, in particular linear, along an adjusting axis, in particular a swivel axis of the bearing, between a fixing position provided for fixing of the coupling arm, in which the fixing element makes form-fitting engagement with at least one mating holding element, and a release position, in which the coupling arm is movable, and wherein the fixing element and the mating holding element or elements have interlocking contours and mating interlocking contours (69, 70) with angular clearance from one another, the fixing element forms a component which is movable relative to the vehicle mounting part (21; 421; 221) and the bearing element (32; 432, 232) which supports the coupling arm, characterised in that the fixing element is movement-coupled to the bearing element (32; 432, 232) carrying the coupling arm, so that the fixing element, during any movement of the bearing element (32; 432, 232), is carried along with it.
A method for measuring fouling in a reactor, said reaction being an organ of an installation for the treatment of a fluid through which a fluid is flowing and which comprises a fouling measuring system comprising: (i) located into the core of the fluid flowing of the reactor, an active probe constituted of a heat generator, cylindrical or flat, onto which external surface a first temperature probe is fastened; and (ii) located near to the heat generator, that is also within the core of the fluid flowing through the reactor, a passive probe consisting in a second temperature probe; and said method comprising the following steps of: a) warming up the wall external surface of said heat generator to a first temperature (θ w), the first temperature (θ w) being measured by means of the first temperature probe and differing at most by +0.5°C as compared to a second temperature (θ b) of the fluid flowing through the reactor when there is no fouling, the second temperature (θ b) being measured by means of the second temperature probe; b) measuring, during the reactor operating time, the temperatures (θ w) and (θ b), respectively, and calculating the difference value (Δθ = θ w - θ b); and c) determining the fouling state of the reactor, which varies depending on the value of Δθ. (i) located into the core of the fluid flowing of the reactor, an active probe constituted of a heat generator, cylindrical or flat, onto which external surface a first temperature probe is fastened; and (ii) located near to the heat generator, that is also within the core of the fluid flowing through the reactor, a passive probe consisting in a second temperature probe; and a) warming up the wall external surface of said heat generator to a first temperature (θ w), the first temperature (θ w) being measured by means of the first temperature probe and differing at most by +0.5°C as compared to a second temperature (θ b) of the fluid flowing through the reactor when there is no fouling, the second temperature (θ b) being measured by means of the second temperature probe; b) measuring, during the reactor operating time, the temperatures (θ w) and (θ b), respectively, and calculating the difference value (Δθ = θ w - θ b); and c) determining the fouling state of the reactor, which varies depending on the value of Δθ.
An end effector of a circular stapling instrument, said end effector comprising: a frame; a cartridge body including staple cavities; staples removably stored in said staple cavities; and a closure drive, comprising: an anvil configured to deform said staples, said anvil comprising a plurality of attachment arms; a trocar shaft movable between an extended position and a retracted position, said trocar shaft comprising an attachment shoulder; characterised in that the closure drive comprises a clip attached to said trocar shaft, wherein said frame is configured to bias said clip into an attachment configuration when said trocar shaft is in said extended position and permit said anvil to be attached to said trocar shaft, and wherein said clip is configured to resiliently expand into a blocking configuration when said trocar shaft is in said retracted position and prevent said anvil from being attached to said trocar shaft, wherein said plurality of attachment arms are configured to engage said attachment shoulder when said clip is in said attachment configuration, and wherein said clip is configured to bias said attachment arms away from said attachment shoulder when said clip is in said blocking configuration. a frame; a cartridge body including staple cavities; staples removably stored in said staple cavities; and a closure drive, comprising: an anvil configured to deform said staples, said anvil comprising a plurality of attachment arms; a trocar shaft movable between an extended position and a retracted position, said trocar shaft comprising an attachment shoulder; characterised in that the closure drive comprises a clip attached to said trocar shaft, an anvil configured to deform said staples, said anvil comprising a plurality of attachment arms; a trocar shaft movable between an extended position and a retracted position, said trocar shaft comprising an attachment shoulder; characterised in that the closure drive comprises a clip attached to said trocar shaft,