A device (200, 300, 400, 500, 600) for rapid concentration of particles and molecules from a sample, the device comprising: an opening (205, 305, 405, 505, 605) for aspirating the sample; a hollow fiber filter (201, 301, 401, 501, 601) coupled to the opening, the filter having a porous surface for capture of particles and molecules from the sample; a permeate chamber located exterior of the hollow fiber filter; a permeate draw (209, 309, 409, 509, 609) in fluid communication with the hollow fiber filter for drawing the sample through the hollow fiber filter and removing permeate from the permeate chamber; wherein, in use, the particles and molecules are eluted from the porous surface and dispensed in a reduced fluid volume through the opening; the device being characterized in that the device either comprises: one or more hydrophobic vents (211, 311, 411, 511, 611) arranged in such a way that a negative pressure applied to the permeate chamber allows air to be drawn through the one or more hydrophobic vents, thereby causing liquid to be aspirated through the opening into the lumen of the hollow fiber filter; or the device comprises: a pump connected to the lumen of the hollow fiber filter for drawing a volume of air out of the lumen of the hollow fiber filter such that the sample is aspirated through the opening towards the top of the hollow fiber filter; a liquid sensor for sensing when the liquid sample reaches the top of the hollow fiber filter; and means for stopping the pump when the liquid sample reaches the top of the hollow fiber filter. an opening (205, 305, 405, 505, 605) for aspirating the sample; a hollow fiber filter (201, 301, 401, 501, 601) coupled to the opening, the filter having a porous surface for capture of particles and molecules from the sample; a permeate chamber located exterior of the hollow fiber filter; a permeate draw (209, 309, 409, 509, 609) in fluid communication with the hollow fiber filter for drawing the sample through the hollow fiber filter and removing permeate from the permeate chamber; wherein, in use, the particles and molecules are eluted from the porous surface and dispensed in a reduced fluid volume through the opening; the device being characterized in that the device either comprises: one or more hydrophobic vents (211, 311, 411, 511, 611) arranged in such a way that a negative pressure applied to the permeate chamber allows air to be drawn through the one or more hydrophobic vents, thereby causing liquid to be aspirated through the opening into the lumen of the hollow fiber filter; or the device comprises: a pump connected to the lumen of the hollow fiber filter for drawing a volume of air out of the lumen of the hollow fiber filter such that the sample is aspirated through the opening towards the top of the hollow fiber filter; a liquid sensor for sensing when the liquid sample reaches the top of the hollow fiber filter; and means for stopping the pump when the liquid sample reaches the top of the hollow fiber filter. a pump connected to the lumen of the hollow fiber filter for drawing a volume of air out of the lumen of the hollow fiber filter such that the sample is aspirated through the opening towards the top of the hollow fiber filter; a liquid sensor for sensing when the liquid sample reaches the top of the hollow fiber filter; and means for stopping the pump when the liquid sample reaches the top of the hollow fiber filter.