mhurhangee/ep-ind-claims huggingface dataset:
A medical device system for determining presence of scar tissue, the system comprising: an implanted lead (118, 120, 122) having a plurality of electrodes (140, 142, 144) positionable in the right or left ventricle for cardiac pacing and sensing: a sensing module for sensing heart activity with a first electrode of the plurality of electrodes to produce a first unipolar electrogram waveform, wherein the sensed heart activity is not a result from pacing of the ventricle in which the first electrode is positioned; a processor configured to receive the first unipolar EGM waveform and extract two or more features from the first unipolar EGM waveform representative of heart activity at the first electrode and identify scar tissue at a site of the first electrode based upon at least two of the extracted features indicating scar tissue, characterised in that said processor is further configured to provide a response to identifying the scar tissue comprising generating a notification of identified scar tissue at the first electrode site and automatically excluding the first electrode for pacing delivery by a delivery module. a sensing module for sensing heart activity with a first electrode of the plurality of electrodes to produce a first unipolar electrogram waveform, wherein the sensed heart activity is not a result from pacing of the ventricle in which the first electrode is positioned; a processor configured to receive the first unipolar EGM waveform and extract two or more features from the first unipolar EGM waveform representative of heart activity at the first electrode and identify scar tissue at a site of the first electrode based upon at least two of the extracted features indicating scar tissue, characterised in that said processor is further configured to provide a response to identifying the scar tissue comprising generating a notification of identified scar tissue at the first electrode site and automatically excluding the first electrode for pacing delivery by a delivery module.
A nozzle storage which has a plurality of storage sections for storing a nozzle palette which is capable of placing a suction nozzle thereon, wherein the plurality of storage sections are installed to be aligned in the vertical direction, and wherein the nozzle storage includes an arm for storing the nozzle palette to the plurality of storage sections, and for taking out the nozzle palette from the plurality of storage sections, characterized in that the nozzle storage includes a first moving mechanism which is configured to move the arm in the vertical direction in which the plurality of storage sections are aligned in a state of opposing the plurality of storage sections, and a second moving mechanism which is configured to move the arm in the horizontal direction of approaching the plurality of storage sections, and in the horizontal direction of being separated from the plurality of storage sections.
Lock device for an electronic locking system, the lock device comprising: - an input member arranged to rotate about an input rotational axis; - an output member arranged to rotate about an output rotational axis; - an energy harvesting arrangement configured to generate electric energy from rotation of the input member in a first direction about the input rotational axis; and - a selective transfer device movable between a locking state, in which the output member cannot be rotated about the output rotational axis by means of rotation of the input member about the input rotational axis, and an unlocking state, in which the output member can be rotated about the output rotational axis by means of rotation of the input member in the first direction about the input rotational axis; wherein the transfer device is powered by the energy harvesting arrangement; and wherein the energy harvesting arrangement comprises: - an electric generator; characterized in that the energy harvesting arrangement further comprises - a drive member arranged to drive the electric generator, the drive member being displaceable by means of the input member from a starting position to a releasing position; - an elastic element arranged to store mechanical energy from the displacement of the drive member from the starting position to the releasing position; and - a release mechanism arranged to release mechanical energy stored in the elastic element to a returning displacement of the drive member when the drive member reaches the releasing position. - an input member arranged to rotate about an input rotational axis; - an output member arranged to rotate about an output rotational axis; - an energy harvesting arrangement configured to generate electric energy from rotation of the input member in a first direction about the input rotational axis; and - a selective transfer device movable between a locking state, in which the output member cannot be rotated about the output rotational axis by means of rotation of the input member about the input rotational axis, and an unlocking state, in which the output member can be rotated about the output rotational axis by means of rotation of the input member in the first direction about the input rotational axis; wherein the transfer device is powered by the energy harvesting arrangement; and wherein the energy harvesting arrangement comprises: - an electric generator; characterized in that the energy harvesting arrangement further comprises - a drive member arranged to drive the electric generator, the drive member being displaceable by means of the input member from a starting position to a releasing position; - an elastic element arranged to store mechanical energy from the displacement of the drive member from the starting position to the releasing position; and - a release mechanism arranged to release mechanical energy stored in the elastic element to a returning displacement of the drive member when the drive member reaches the releasing position.
A computerized method for analyzing the beating of a derived human cardiomyocyte, the method comprising capturing a sequence of images depicting the derived human cardiomyocyte over an analysis period, obtaining information indicative of the region of the images depicting the derived human cardiomyocyte, obtaining information indicative of two or more sub-regions within said region, and determining at least one signal descriptive of the beating of the derived human cardiomyocyte during the analysis period on basis of the sequence of captured images, comprising determining two or more signals characterizing the displacement within a region of the images depicting the derived human cardiomyocyte, said two or more signals characterizing the extent of displacement within a respective sub-region of said region as a function of time, wherein said sub-regions are intersections of said region and sectors of a circle having its center in the focus point of the motion of the derived human cardiomyocyte, wherein, for a given sub-region, said two or more signals characterize the extent of displacement along a first axis that is a radial axis with respect to the focus point of the motion within the respective sector and the extent of displacement along a second axis that is a normal of the first axis.
A method for manufacturing a vane made of composite material for a turbomachine, in particular for an aircraft, comprising the steps of: - weaving fibres in three dimensions so as to produce a fibrous preform, - mounting the fibrous preform in a mould, - injecting, in the mould, a resin, in order to impregnate the fibrous preform, - polymerizing the resin so as to form the vane, said vane comprising a blade having a pressure face and a suction face extending between a leading edge and a trailing edge, a longitudinal end of said blade being connected to a platform (112, 114), the platform comprising pressure and suction segments connected to said blade by a connection fillet, and a separation being formed in said fibrous preform between said pressure and suction segments of the platform, - reinforcing the leading edge of said blade, by integrating a first metallic reinforcement on the leading edge of the blade, characterised in that the method also comprises the step of: - reinforcing the connection fillets, by integrating a second metallic reinforcement (126, 128, 130, 132) on at least one portion of the pressure and suction segments of the platform and in the separation. - weaving fibres in three dimensions so as to produce a fibrous preform, - mounting the fibrous preform in a mould, - injecting, in the mould, a resin, in order to impregnate the fibrous preform, - polymerizing the resin so as to form the vane, said vane comprising a blade having a pressure face and a suction face extending between a leading edge and a trailing edge, a longitudinal end of said blade being connected to a platform (112, 114), the platform comprising pressure and suction segments connected to said blade by a connection fillet, and a separation being formed in said fibrous preform between said pressure and suction segments of the platform, - reinforcing the leading edge of said blade, by integrating a first metallic reinforcement on the leading edge of the blade, - reinforcing the connection fillets, by integrating a second metallic reinforcement (126, 128, 130, 132) on at least one portion of the pressure and suction segments of the platform and in the separation.
Spray head for spraying a product in a spraying direction, for example a cosmetic product, in particular a deodorant, this spray head comprising: - a body, comprising: - a channel for conveying the product, - a housing in which the conveying channel emerges, the spray head also comprising: - a spray nozzle mounted on the housing, this nozzle comprising at least two, better still three, spray orifices, respective feed channels being formed between the nozzle and the body, these channels connecting the conveying channel to the said corresponding spray orifices, and being obliquely inclined relative to the spraying direction. - a body, comprising: - a channel for conveying the product, - a housing in which the conveying channel emerges, the spray head also comprising: - a channel for conveying the product, - a housing in which the conveying channel emerges, the spray head also comprising: - a spray nozzle mounted on the housing, this nozzle comprising at least two, better still three, spray orifices, respective feed channels being formed between the nozzle and the body, these channels connecting the conveying channel to the said corresponding spray orifices, and being obliquely inclined relative to the spraying direction.
Rotary joint prosthesis comprising a distal first component for anchoring to a first bone, a proximal second component for anchoring to a second bone, and a coupling piece which, with the first component, forms a flexion bearing about a first axis and, with the second component, forms a rotary bearing, formed by pin and bearing bush, about a second axis oriented transversely with respect to the first axis, wherein the rotary bearing comprises a multi-layer bearing insert, with a sliding sleeve surrounding the pin, and a support sleeve that encloses said sliding sleeve and is fastened to the coupling piece by a securing element, characterized in that the securing element has an actuation member within the support sleeve and can be connected to the coupling piece such as to ensure tensile strength via two aligned bores (47, 38) in support sleeve and coupling piece.
A proof mass assembly (10, 50, 110) comprising a quartz substrate, the quartz substrate comprising: a proof mass (12, 112); a proof mass support; a flexure (16, 16a, 16b) connecting the proof mass to the proof mass support, wherein the proof mass is configured to rotate relative to the proof mass support via the flexure; a first resonator connected to a first major surface of the proof mass and a first major surface of the proof mass support; a second resonator connected to a second major surface of the proof mass and a second major surface of the proof mass support; and a strain isolator (24a, 24b) connected to the proof mass support and configured to reduce a strain, compression or tension force of at least one of the proof mass, the proof mass support, the flexure, the first resonator, or the second resonator upon application of a force to the proof mass assembly. a proof mass (12, 112); a proof mass support; a flexure (16, 16a, 16b) connecting the proof mass to the proof mass support, wherein the proof mass is configured to rotate relative to the proof mass support via the flexure; a first resonator connected to a first major surface of the proof mass and a first major surface of the proof mass support; a second resonator connected to a second major surface of the proof mass and a second major surface of the proof mass support; and a strain isolator (24a, 24b) connected to the proof mass support and configured to reduce a strain, compression or tension force of at least one of the proof mass, the proof mass support, the flexure, the first resonator, or the second resonator upon application of a force to the proof mass assembly.
A process for the preparation of 16-methylene-17α-ethynyl-17β-hydroxy steroids, which comprises (a) treating a 16-methylene-17-keto steroid with a compound of formula wherein each R is independently selected from substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted aryl and halogen, and (b) desilylating the resulting 16-methylene-17α-silylethynyl-17β-hydroxy steroid. (a) treating a 16-methylene-17-keto steroid with a compound of formula wherein each R is independently selected from substituted or unsubstituted C 1 -C 6 alkyl, substituted or unsubstituted aryl and halogen, and (b) desilylating the resulting 16-methylene-17α-silylethynyl-17β-hydroxy steroid.
A method for determining parameter values in voxels of an examination object using a magnetic resonance fingerprinting technique includes the steps of: - establishing, with the aid of an MRF capture method, at least one voxel time series from which a respective value (P, P') of at least three parameters at the location in the examination object represented by the respective voxel are to be determined, wherein the voxel time series is/are established such that the signal characteristics of the voxel time series display dependences on the parameters to be determined, - performing a first signal comparison of at least one segment of a respective signal characteristic of the established voxel time series with a corresponding segment of first comparison signal characteristics in order to determine the respective values of at least a first one of the parameters to be determined, - generating further comparison signal characteristics (D') on the basis of the first comparison signal characteristics and values determined in the first signal comparison, - performing a further signal comparison of at least one segment of a respective signal characteristic of the established voxel time series with a corresponding segment of the generated further comparison signal characteristics (D') in order to determine respectively the values of at least a first further parameter and a second further parameter of the parameters to be determined, - outputting the values determined for the respective voxel of the parameters to be determined. - establishing, with the aid of an MRF capture method, at least one voxel time series from which a respective value (P, P') of at least three parameters at the location in the examination object represented by the respective voxel are to be determined, wherein the voxel time series is/are established such that the signal characteristics of the voxel time series display dependences on the parameters to be determined, - performing a first signal comparison of at least one segment of a respective signal characteristic of the established voxel time series with a corresponding segment of first comparison signal characteristics in order to determine the respective values of at least a first one of the parameters to be determined, - generating further comparison signal characteristics (D') on the basis of the first comparison signal characteristics and values determined in the first signal comparison, - performing a further signal comparison of at least one segment of a respective signal characteristic of the established voxel time series with a corresponding segment of the generated further comparison signal characteristics (D') in order to determine respectively the values of at least a first further parameter and a second further parameter of the parameters to be determined, - outputting the values determined for the respective voxel of the parameters to be determined.
A capsule (1; 101; 201) for insertion into a bore of a porous element to apply treatment substance to the interior of the element, and having a container (2; 102; 202), with at least one internal cavity (3; 203) for receiving treatment substance therein, a first releasably closed insertion end (1A; 101A; 201A) and an outer stop flange (8; 108; 208), and a plug (4; 104; 204) received in and fixed to the container through a common interconnecting land (5; 205), characterized in that a first container shank portion (6; 106; 206) extending from a first insertion end (1A; 101A; 201A) of the capsule and up to the area of the interconnecting land has a uniform generally cylindrical shape, and a second container shank portion (7; 107; 207) extending away from said container first shank portion, from the area of the interconnecting land towards the outer stop flange, at least at an inner surface (7B; 107B; 207B) thereof has an outwardly slightly diverging, conical shape and at an outer surface (7A; 107A; 207A) thereof, separated a short distance from the outer stop flange, has a first circumferential beveled edge (9; 109; 209) serving as a transition to an outer increased diameter section (7C; 107C; 207C).
Inverter for centrally converting and feeding a grid-compatible AC voltage into a grid, comprising: - an inverter bridge for converting a DC voltage to a first AC voltage and - a grid interface between the inverter bridge and the grid for converting the first AC voltage to the grid-compatible AC voltage for feeding into the grid, characterized in that an AC interface via which a decentralized AC module for feeding into the grid can be connected, is arranged between the inverter bridge and the grid interface. - an inverter bridge for converting a DC voltage to a first AC voltage and - a grid interface between the inverter bridge and the grid for converting the first AC voltage to the grid-compatible AC voltage for feeding into the grid,
1. Fenofibrate for use in the treatment of a neurodegenerative disease by inducing PGC-1α expression in a neural cell or population of neural cells of a subject having a neurodegenerative disease and decreased PGC-1α expression, as compared to a subject not having the neurodegenerative disease.
A printing system for forming a three-dimensional object, comprising: a. a laser light source; b. a substrate in optical communication with said laser light source; characterised by: c. the laser light source generating a coherent beam of visible light, having a wavelength between 380 nm and 760 nm, by stimulated Raman scattering; d. a scanning module downstream of said laser light source, wherein said scanning module is adapted to generate a scanning motion of said coherent beam of visible light with respect to said substrate, which scanning motion corresponds to a predetermined shape of said three-dimensional object; and e. a computer control system operatively coupled to said laser light source and said scanning module, wherein said computer control system is programmed to (i) control said scanning motion in a predetermined manner and (ii) modulate a power of said laser light source, to form said object from said substrate. a. a laser light source; b. a substrate in optical communication with said laser light source; c. the laser light source generating a coherent beam of visible light, having a wavelength between 380 nm and 760 nm, by stimulated Raman scattering; d. a scanning module downstream of said laser light source, wherein said scanning module is adapted to generate a scanning motion of said coherent beam of visible light with respect to said substrate, which scanning motion corresponds to a predetermined shape of said three-dimensional object; and e. a computer control system operatively coupled to said laser light source and said scanning module, wherein said computer control system is programmed to (i) control said scanning motion in a predetermined manner and (ii) modulate a power of said laser light source, to form said object from said substrate.
A branch predictor, comprising: a plurality of memory banks having entries that hold prediction information for predicting a direction of branch instructions fetched and executed by a processor that comprises the branch predictor; a counter of events that occur in the processor; hardware logic which is configured for performing an arithmetic and/or logical operation on predetermined bits of the counter to generate a random value; and wherein in response to the processor determining the direction of a branch instruction predicted by the branch predictor, the branch predictor is configured for using the random value generated by the hardware logic to make a decision about updating the memory banks; wherein a branch history pattern that specifies a history of directions of branch instructions encountered by the processor; and wherein the hardware logic, in addition to performing the arithmetic and/or logical operation on predetermined bits of the counter, is configured for performing the arithmetic and/or logical operation also on predetermined bits of the branch history pattern to generate the random value; wherein the arithmetic and/or logical operation comprises a Boolean exclusive-OR operation of a first portion of bits of the counter with a second portion of bits of the counter, wherein the event counted comprises a retire of an instruction by the processor. a plurality of memory banks having entries that hold prediction information for predicting a direction of branch instructions fetched and executed by a processor that comprises the branch predictor; a counter of events that occur in the processor; hardware logic which is configured for performing an arithmetic and/or logical operation on predetermined bits of the counter to generate a random value; and wherein in response to the processor determining the direction of a branch instruction predicted by the branch predictor, the branch predictor is configured for using the random value generated by the hardware logic to make a decision about updating the memory banks; wherein a branch history pattern that specifies a history of directions of branch instructions encountered by the processor; and wherein the hardware logic, in addition to performing the arithmetic and/or logical operation on predetermined bits of the counter, is configured for performing the arithmetic and/or logical operation also on predetermined bits of the branch history pattern to generate the random value; wherein the arithmetic and/or logical operation comprises a Boolean exclusive-OR operation of a first portion of bits of the counter with a second portion of bits of the counter, wherein the event counted comprises a retire of an instruction by the processor.