An ophthalmic injection system comprising: a tip segment connectable to and removable from a limited reuse assembly, the tip segment comprising: a disnensincr chamber having an inner surface and an outer surface, the inner surface defining a cavity for receiving a quantity of a substance fluidly coupled to a needle; a plunger engaged with the inner surface of the dispensing chamber, the plunger capable of sliding in the cavity of the dispensing chamber, the plunger fluidly sealed to the inner surface of the dispensing chamber, the plunger having a proximate end and a distal end; a first housing at least partially enclosing the dispensing chamber and the plunger; the proximate end of the plunger having a first mechanical linkage interface; a heater in thermal contact with the dispensing chamber, the heater for heating the substance; and a tip interface connector electrically connected to the heater; the limited reuse assembly comprising: a power source; a controller for controlling the operation of the system; a limited reuse assembly interface connector, the limited reuse assembly interface connector adapted to connect to the tip interface connector; a motor having a shaft; a second housing at least partially enclosing the controller and the motor; a second mechanical linkage interface located on an end of the shaft connected to the motor shaft, actuatable by the motor, wherein said second mechanical linkage interface is mateable and separable from said first mechanical linkage interface, such that when the tip segment is connected to the reusable assembly, the motor is in turn adapted to move the plunger upward toward needle. a tip segment connectable to and removable from a limited reuse assembly, the tip segment comprising: a disnensincr chamber having an inner surface and an outer surface, the inner surface defining a cavity for receiving a quantity of a substance fluidly coupled to a needle; a plunger engaged with the inner surface of the dispensing chamber, the plunger capable of sliding in the cavity of the dispensing chamber, the plunger fluidly sealed to the inner surface of the dispensing chamber, the plunger having a proximate end and a distal end; a first housing at least partially enclosing the dispensing chamber and the plunger; the proximate end of the plunger having a first mechanical linkage interface; a heater in thermal contact with the dispensing chamber, the heater for heating the substance; and a tip interface connector electrically connected to the heater; the limited reuse assembly comprising: a power source; a controller for controlling the operation of the system; a limited reuse assembly interface connector, the limited reuse assembly interface connector adapted to connect to the tip interface connector; a motor having a shaft; a second housing at least partially enclosing the controller and the motor; a second mechanical linkage interface located on an end of the shaft connected to the motor shaft, actuatable by the motor, wherein said second mechanical linkage interface is mateable and separable from said first mechanical linkage interface, such that when the tip segment is connected to the reusable assembly, the motor is in turn adapted to move the plunger upward toward needle. a disnensincr chamber having an inner surface and an outer surface, the inner surface defining a cavity for receiving a quantity of a substance fluidly coupled to a needle; a plunger engaged with the inner surface of the dispensing chamber, the plunger capable of sliding in the cavity of the dispensing chamber, the plunger fluidly sealed to the inner surface of the dispensing chamber, the plunger having a proximate end and a distal end; a first housing at least partially enclosing the dispensing chamber and the plunger; the proximate end of the plunger having a first mechanical linkage interface; a heater in thermal contact with the dispensing chamber, the heater for heating the substance; and a tip interface connector electrically connected to the heater; the limited reuse assembly comprising: a power source; a controller for controlling the operation of the system; a limited reuse assembly interface connector, the limited reuse assembly interface connector adapted to connect to the tip interface connector; a motor having a shaft; a second housing at least partially enclosing the controller and the motor; a second mechanical linkage interface located on an end of the shaft connected to the motor shaft, actuatable by the motor, wherein said second mechanical linkage interface is mateable and separable from said first mechanical linkage interface, such that when the tip segment is connected to the reusable assembly, the motor is in turn adapted to move the plunger upward toward needle. a power source; a controller for controlling the operation of the system; a limited reuse assembly interface connector, the limited reuse assembly interface connector adapted to connect to the tip interface connector; a motor having a shaft; a second housing at least partially enclosing the controller and the motor; a second mechanical linkage interface located on an end of the shaft connected to the motor shaft, actuatable by the motor, wherein said second mechanical linkage interface is mateable and separable from said first mechanical linkage interface, such that when the tip segment is connected to the reusable assembly, the motor is in turn adapted to move the plunger upward toward needle.