mhurhangee/ep-ind-claims huggingface dataset:
A system comprising a processor, wherein the processor includes: processor means for controlling an electrical stimulation module to deliver a pacing stimulus to a first ventricle of a heart of a patient; after the electrical stimulation module delivers the pacing stimulus to the first ventricle, processor means for determining, whether a surrogate indication of intrinsic conduction from an atrium of the heart of the patient is detected, wherein the determining whether the surrogate indication of the intrinsic conduction from the atrium is detected comprises detecting activation of a second ventricle of the heart within a predetermined window of time immediately following delivery of the pacing stimulus to the first ventricle; and processor means for controlling cardiac resynchronization therapy delivered by the electrical stimulation module to the patient based on whether the surrogate indication of intrinsic conduction from the atrium is detected. processor means for controlling an electrical stimulation module to deliver a pacing stimulus to a first ventricle of a heart of a patient; after the electrical stimulation module delivers the pacing stimulus to the first ventricle, processor means for determining, whether a surrogate indication of intrinsic conduction from an atrium of the heart of the patient is detected, wherein the determining whether the surrogate indication of the intrinsic conduction from the atrium is detected comprises detecting activation of a second ventricle of the heart within a predetermined window of time immediately following delivery of the pacing stimulus to the first ventricle; and processor means for controlling cardiac resynchronization therapy delivered by the electrical stimulation module to the patient based on whether the surrogate indication of intrinsic conduction from the atrium is detected.
A method suitable for preparing a specimen for inspection, the method comprising the steps of: irradiating a photocathode so that the photocathode emits electrons from a surface of the photocathode, wherein the emitted electrons each follow a trajectory, and the trajectories of the electrons are such that they can be extrapolated to intersect at a region within the photocathode, the region defining a virtual source, and wherein the photocathode comprises a rounded tip which has a radius of curvature; configuring the emitted electrons so that they form an electron beam; focusing the electron beam onto a specimen to form an image of the virtual source on the specimen. irradiating a photocathode so that the photocathode emits electrons from a surface of the photocathode, wherein the emitted electrons each follow a trajectory, and the trajectories of the electrons are such that they can be extrapolated to intersect at a region within the photocathode, the region defining a virtual source, and wherein the photocathode comprises a rounded tip which has a radius of curvature; configuring the emitted electrons so that they form an electron beam; focusing the electron beam onto a specimen to form an image of the virtual source on the specimen.
An electric actuator (10, 10A) comprising a sliding screw shaft (18, 102), and a nut (52, 138) screw-engaged with the sliding screw shaft (18, 102), the sliding screw shaft (18, 102) being configured to rotate under operation of a motor to thereby cause the nut (52, 138) to be displaced in an axial direction of the sliding screw shaft (18, 102), wherein the sliding screw shaft (18, 102) is made of light metal or light metal alloy; and a diamond-like carbon film (60, 170) is formed on a region of a threaded part (58, 168) of the nut (52, 138), the region being located within a range from a starting end of the threaded part (58, 168) of the nut (52, 138) in an axial direction thereof to at least a third thread of the threaded part (58, 168) of the nut (52, 138), characterized in that a thickness of the diamond-like carbon film (60, 170) on a first starting end portion (58a, 168a) of the threaded part (58, 168) of the nut (52, 138) that is located at a first thread from the starting end is larger than a thickness of the diamond-like carbon film (60, 170) on a second starting end portion (58b, 168b) of the threaded part (58, 168) of the nut (52, 138) that is located at a second thread from the starting end.
A method for detecting faults or operational parameters in a pump assembly (20, 20', 120) including an electric motor and a pump by use of a handheld communication device (30, 130) running a software app, wherein the pump assembly or electric motor has at least one rotating shaft, the method comprising: a) contactless measuring a sound signal emanating from the pump assembly by use of a microphone (32, 132) connected to or implemented in the handheld communication device, b) processing the measured sound signal by a processing unit implemented in the handheld communication device and the software app installed on the handheld communication device (30, 130), and c) recognising one or more sound emanating conditions including any possible faults by way of the processed sound signal, characterized in that the handheld communication device provides a feedback, e.g. an audial, visual or vibrational feedback, when an acceptable measurement position of the microphone has been found determined by a minimum threshold value for the measured sound signal. a) contactless measuring a sound signal emanating from the pump assembly by use of a microphone (32, 132) connected to or implemented in the handheld communication device, b) processing the measured sound signal by a processing unit implemented in the handheld communication device and the software app installed on the handheld communication device (30, 130), and c) recognising one or more sound emanating conditions including any possible faults by way of the processed sound signal,
Personal care aid when showering comprising - a straight cylindrical moulded part with two flanges (2.3, 2.4) arranged in a plane, wherein fastening sections (2.5, 2.6) extend from the plane from the flanges (2.3, 2.4) and the two opposite fastening sections (2.5, 2.6) are connected to one another via a section (2.7) having a curved cross-section, - a washcloth stretched over the curved section (2.7), - a Velcro connection exclusively between the lateral edges (3.1, 3.2) of the washcloth and the fastening sections (2.5, 2.6), - at least two suction cups attached to each of the two flanges (2.3, 2.4), adapted for temporarily fixing the moulded part to a smooth surface. - a straight cylindrical moulded part with two flanges (2.3, 2.4) arranged in a plane, wherein fastening sections (2.5, 2.6) extend from the plane from the flanges (2.3, 2.4) and the two opposite fastening sections (2.5, 2.6) are connected to one another via a section (2.7) having a curved cross-section, - a washcloth stretched over the curved section (2.7), - a Velcro connection exclusively between the lateral edges (3.1, 3.2) of the washcloth and the fastening sections (2.5, 2.6), - at least two suction cups attached to each of the two flanges (2.3, 2.4), adapted for temporarily fixing the moulded part to a smooth surface.
A potentiometric nucleic acid sequencing method comprising the steps of: a. providing a sample comprising a template nucleic acid to be sequenced; b. annealing a primer molecule to said template nucleic acid, or creating a nick in the non-template strand for a site-specific elongation; c. carrying out nucleic acid elongation steps with a polymerase on said template in the presence of free metal ions, wherein each step comprises the addition of a single type of nucleotide, wherein pyrophosphate is released in a stoichiometric ratio to the number of nucleotides incorporated, and wherein the metal ions are capable of preferentially binding to pyrophosphate in solution; d. determining in said sample the potential, current or charge at an electrode at least twice, wherein between the first time and the second time one or more elongation steps take place or, alternatively, determining the potential, current or charge continuously; and e. correlating the change in potential, current or charge over the number of elongation steps with the type of nucleotides added. wherein the metal ions that bind to pyrophosphate are from the group comprising manganese ions, aluminium ions, tin ions, and iron ions and the working electrodes are selective for the metal ion used. a. providing a sample comprising a template nucleic acid to be sequenced; b. annealing a primer molecule to said template nucleic acid, or creating a nick in the non-template strand for a site-specific elongation; c. carrying out nucleic acid elongation steps with a polymerase on said template in the presence of free metal ions, wherein each step comprises the addition of a single type of nucleotide, wherein pyrophosphate is released in a stoichiometric ratio to the number of nucleotides incorporated, and wherein the metal ions are capable of preferentially binding to pyrophosphate in solution; d. determining in said sample the potential, current or charge at an electrode at least twice, wherein between the first time and the second time one or more elongation steps take place or, alternatively, determining the potential, current or charge continuously; and e. correlating the change in potential, current or charge over the number of elongation steps with the type of nucleotides added.
A method for adjusting operation parameters of an injection internal combustion engine, including the following steps: - setting a stability setpoint Cs, - calculating an engine stability index Is, - calculating the stability deviation Es equal to the difference between the stability setpoint Cs and the stability index Is, - processing the stability deviation Es using a regulator that provides a setpoint to be applied for one of the operation parameters of the engine, said parameter being selected by a computer, or supervisor, that controls the adjustment so that the corrective action applied optimizes the level of emission of pollutants and/or the thermal energy available at the exhaust, while respecting the stability setpoint Cs, the method being such that, with each parameter varying within an interval defined by two threshold values, when a parameter reaches a threshold value under the effect of a first corrective action, the computer that controls the adjustment then selects another parameter for which a setpoint to be applied will be determined in a similar manner. - setting a stability setpoint Cs, - calculating an engine stability index Is, - calculating the stability deviation Es equal to the difference between the stability setpoint Cs and the stability index Is, - processing the stability deviation Es using a regulator that provides a setpoint to be applied for one of the operation parameters of the engine, said parameter being selected by a computer, or supervisor, that controls the adjustment so that the corrective action applied optimizes the level of emission of pollutants and/or the thermal energy available at the exhaust, while respecting the stability setpoint Cs,
Method for determination of deposits on an ultrasound transducer during the operation thereof, characterised in that a conductance of the ultrasound transducer is determined by means of an impedance spectroscopy, wherein, on the basis of the conductance, an attenuation and a resonance ( Ω) of the ultrasound transducer is determined and wherein the resonance ( Ω) is plotted against the attenuation in a coordinate system and, on the basis of reference points resulting thereby, possible deposits are inferred.
Motor vehicle steering system comprising a steering shaft consisting of several shaft components (1, 2) non-rotatably connected to one another, wherein one end of a shaft component has on its outer circumference a splined shaft profile oriented in the axial direction and is thereby inserted into a sleeve-shaped intermediate piece, which is located on the other shaft component adjoining it in the longitudinal direction of the steering shaft and having on its inner circumference a splined shaft profile with a shape which is a negative of the splined shaft profile of the shaft component, so that the shaft component is joined to the intermediate piece by a plug-in connection, wherein a continuous guide contour, which points towards the intermediate piece and is located in front of the splined shaft profile towards the intermediate piece, is formed on the shaft component, characterised in that the guide contour is broken by grooves of the splined shaft profile while forming convex guide segments.
An ICV formulation for use in the treatment of Hunter Syndrome, comprising Idursulfase-beta (IDS-β) protein at a concentration of 15 mg/ml, Sodium chloride at a concentration of 150 mM, polysorbate 20 at a concentration of 0.05 mg/ml, phosphate at a concentration no greater than 5mM and a pH of 6, wherein said formulation is administered intracerebroventricularly (ICV administration) to a subject in need of treatment in a therapeutically effective dose, wherein said ICV administration is through an intraventricular catheter system comprising a reservoir and a catheter connected to said reservoir.
A fuel delivery system for regenerating a vehicle exhaust component comprising: a source of pressurized fuel; a first fuel injector in fluid communication with said source of pressurized fuel; a check valve downstream of said first fuel injector, the check valve having a first predetermined set pressure to open and a second predetermined set pressure to close, said first predetermined set pressure being greater than said second predetermined set pressure, an airless nozzle configured to spray fuel droplets when said valve is open; a second fuel injector downstream of said first fuel injector; and a controller configured to generate a first control signal to open said first fuel injector to supply fuel to said nozzle via said valve to spray fuel droplets and subsequently generate a second control signal to close said first fuel injector and open said second fuel injector to shut off the spray of fuel droplets, wherein when said first fuel injector opens said second fuel injector is closed, so that fuel pressure increases until the fuel pressure reaches said first predetermined set pressure to open said check valve. a source of pressurized fuel; a first fuel injector in fluid communication with said source of pressurized fuel; a check valve downstream of said first fuel injector, the check valve having a first predetermined set pressure to open and a second predetermined set pressure to close, said first predetermined set pressure being greater than said second predetermined set pressure, an airless nozzle configured to spray fuel droplets when said valve is open; a second fuel injector downstream of said first fuel injector; and a controller configured to generate a first control signal to open said first fuel injector to supply fuel to said nozzle via said valve to spray fuel droplets and subsequently generate a second control signal to close said first fuel injector and open said second fuel injector to shut off the spray of fuel droplets, wherein when said first fuel injector opens said second fuel injector is closed, so that fuel pressure increases until the fuel pressure reaches said first predetermined set pressure to open said check valve.
A solid pharmaceutical preparation of a bilayer tablet comprising: (i) an immediate release part containing 10 -55 wt.-% tramadol or a pharmaceutically acceptable salt thereof, 15-45 wt.-% partially pregelatinized starch, 8-74 wt.-% microcrystalline cellulose or a combination of 5-50 wt.-% lactose and 3-25 wt.-% microcrystalline cellulose, and 0.5-3 wt.-% hydroxypropylcellulose, per 100 wt.-% of the immediate release part; and (ii) a sustained release part. (i) an immediate release part containing 10 -55 wt.-% tramadol or a pharmaceutically acceptable salt thereof, 15-45 wt.-% partially pregelatinized starch, 8-74 wt.-% microcrystalline cellulose or a combination of 5-50 wt.-% lactose and 3-25 wt.-% microcrystalline cellulose, and 0.5-3 wt.-% hydroxypropylcellulose, per 100 wt.-% of the immediate release part; and -55 wt.-% tramadol or a pharmaceutically acceptable salt thereof, 15-45 wt.-% partially pregelatinized starch, 8-74 wt.-% microcrystalline cellulose or a combination of 5-50 wt.-% lactose and 3-25 wt.-% microcrystalline cellulose, and 0.5-3 wt.-% hydroxypropylcellulose, (ii) a sustained release part.
A method for operating a system for the synthesis of methanol, wherein a stream of synthesis gas containing hydrogen and oxides of carbon is supplied to a synthesis gas compressor of the system in order to raise the pressure of the synthesis gas stream, wherein the pressurised synthesis gas stream is supplied to a methanol reactor assembly of the system for partial conversion into methanol, and wherein the system has a hydrogen recovery assembly which produces a H recycle stream containing hydrogen from a recovery stream supplied from the methanol reactor assembly, at least a portion of which hydrogen being converted into methanol, characterized in that in the event of a breakdown of the synthesis gas compressor, the synthesis gas stream continues to be supplied to the methanol reactor assembly for partial conversion into methanol, and in that after the breakdown of the synthesis gas compressor, a pipeline assembly of the system is switched in, in a manner such that the H recycle stream is adjusted in order to compensate for a loss of pressure in the methanol reactor assembly.
An antibody that specifically binds a de-N-acetylated sialic acid (deNAc SA) epitope on an extracellularly accessible surface of a cancerous cell present in a subject, for use in a method of treatment for inhibiting growth of a cancerous cell in said subject by administration to said subject of a pharmaceutically acceptable formulation comprising said antibody such that said administering facilitates reduction in viability of cancerous cells bound by the antibody wherein said antibody is reactive with the following structures: and
A pole member holder for holding pole members; wherein a pole member comprises at least a flange portion joined to a main portion for receiving turns of coils during winding; - the pole member holder comprising: - a main body with a plurality of seats; wherein each seat is configured to receive the flange portion of the pole members; - a plurality of base members assembled on the main body, each base member being configured to be assembled adjacent to a lower end (13b") of the flange portion of the respective pole member for engaging the lower end (13b") of the flange portion; - pushing means associated with each seat for pushing the base members to push the pole members; - locking means associated with each seat for engaging and referencing an upper end of the pole members, said pole member holder characterized in that the locking means is provided with a common reference surface of a border arranged to reference the upper ends of the flange portions of the pole members, each base member arranged to push the lower end (13b") of the respective flange portion upwards for causing the upper end to engage against the common reference surface of the border. - the pole member holder comprising: - a main body with a plurality of seats; wherein each seat is configured to receive the flange portion of the pole members; - a plurality of base members assembled on the main body, each base member being configured to be assembled adjacent to a lower end (13b") of the flange portion of the respective pole member for engaging the lower end (13b") of the flange portion; - pushing means associated with each seat for pushing the base members to push the pole members; - locking means associated with each seat for engaging and referencing an upper end of the pole members, said pole member holder characterized in that the locking means is provided with a common reference surface of a border arranged to reference the upper ends of the flange portions of the pole members, each base member arranged to push the lower end (13b") of the respective flange portion upwards for causing the upper end to engage against the common reference surface of the border.
A method of producing a plate composite with the use of cellulose and carbon particles with increased fire resistance characterized in that 1.1. particles rich in elemental carbon, i.e. with a carbon content >90%, selected from expanding graphite and carbon nanotubes, are dispersed in water in weight ratios ranging from 0.2:1 to 1:0.2. in an aqueous system, the weight ratio of carbon particles to water is from 1:1 to 100:1. 1.2. cellulose pulp with a concentration of 1-25% in water is produced 1.3. a dispersed suspension of carbon particles is introduced into the cellulose pulp. 1.4. a composite is formed on a paper machine 1.5. the composite is dried and pressed wherein the EG/CNT dispersion is kept in water for a period of 24 hours, and further the resulting particle dispersion is homogenized for 30-45 s by means of a homogenizer with a rotation speed from 400 to 4000 rpm until a homogeneous water dispersion is obtained and the homogeneous particle dispersion is added to the cellulose pulp produced in parallel in an amount of 1-75% by weight based on the total mass of the product and the mixture is further grounded for 10 s in the refiner, and the cellulose pulp is produced in such a way that the cellulose in the form of sheets is initially comminuted into particles size 1-4 cm 2, soaked for 24 hours in deionized water, the weight ratio of cellulose to water is 1:10, and after 24 hours the cellulose is defibrated in a defiberizer and water is added until the total cellulose to water ratio is at the level of 1:50, then the homogeneous mass is transferred to a sheet forming apparatus and diluted with water to a mass concentration ranging from 2-20%, and cellulose-carbon sheets are formed. 1.1. particles rich in elemental carbon, i.e. with a carbon content >90%, selected from expanding graphite and carbon nanotubes, are dispersed in water in weight ratios ranging from 0.2:1 to 1:0.2. in an aqueous system, the weight ratio of carbon particles to water is from 1:1 to 100:1. 1.2. cellulose pulp with a concentration of 1-25% in water is produced 1.3. a dispersed suspension of carbon particles is introduced into the cellulose pulp. 1.4. a composite is formed on a paper machine 1.5. the composite is dried and pressed
A pharmaceutical composition for use in the treatment of tuberculosis in a treatment regimen, comprising a therapeutically effective amount of each of linezolid, bedaquiline and pretomanid, and optionally pyrazinamide, or a pharmaceutically acceptable salt of each thereof, and a pharmaceutically acceptable carrier, wherein linezolid is removed from the treatment regimen after one to two months.