Process for preparing nano- or microparticles comprising a carrier-polymer and a biologically active ingredient, wherein the process is a solvent emulsion process comprising an organic phase and an aqueous phase to form an emulsion, wherein, in the case of an oil-in-water emulsion (O/W), the organic phase comprises the biologically active ingredient dissolved or dispersed therein or wherein, in the case of a water-in-oil emulsion (W 1 /O), the aqueous phase comprises the biologically active ingredient dissolved or dispersed therein, comprising the steps: a) providing the organic phase comprising a partially water-miscible organic solvent or solvent mixture, wherein the organic phase is saturated with the aqueous phase and wherein the organic phase comprises the carrier-polymer and optionally the biologically active ingredient dissolved or dispersed therein, b) providing the aqueous phase, comprising an aqueous solvent or solvent mixture, comprising water and a pharmaceutically acceptable salt dissolved therein, wherein the salt-containing aqueous phase is further saturated with the solvent or solvent mixture of the organic phase and is comprising an emulsion-stabilizing agent and optionally the biologically active ingredient dissolved or dispersed therein, c) mixing the organic phase and the aqueous phase to gain an oil-in-water emulsion (O/W) or a water-in-oil emulsion (W 1 /O), d) in the case of a water-in-oil emulsion (W 1 /O), addition of an excess of further aqueous phase to gain a water-in-oil-in-water emulsion (W 1 /O/W 2), e) removing the organic solvent or solvent mixture from the oil-in-water emulsion (O/W) from step c) or from the water-in-oil-in-water emulsion (W 1 /O/W 2) from step d) by evaporation and/or extraction to promote the formation of nano- or microparticles comprising the carrier polymer and the biologically active ingredient in a remaining aqueous suspension, f) separating the nano- or microparticles from the aqueous suspension. a) providing the organic phase comprising a partially water-miscible organic solvent or solvent mixture, wherein the organic phase is saturated with the aqueous phase and wherein the organic phase comprises the carrier-polymer and optionally the biologically active ingredient dissolved or dispersed therein, b) providing the aqueous phase, comprising an aqueous solvent or solvent mixture, comprising water and a pharmaceutically acceptable salt dissolved therein, wherein the salt-containing aqueous phase is further saturated with the solvent or solvent mixture of the organic phase and is comprising an emulsion-stabilizing agent and optionally the biologically active ingredient dissolved or dispersed therein, c) mixing the organic phase and the aqueous phase to gain an oil-in-water emulsion (O/W) or a water-in-oil emulsion (W 1 /O), d) in the case of a water-in-oil emulsion (W 1 /O), addition of an excess of further aqueous phase to gain a water-in-oil-in-water emulsion (W 1 /O/W 2), e) removing the organic solvent or solvent mixture from the oil-in-water emulsion (O/W) from step c) or from the water-in-oil-in-water emulsion (W 1 /O/W 2) from step d) by evaporation and/or extraction to promote the formation of nano- or microparticles comprising the carrier polymer and the biologically active ingredient in a remaining aqueous suspension, f) separating the nano- or microparticles from the aqueous suspension.