A delivery device of a self-expanding prosthesis, comprising a catheter and a handle connected to the catheter, wherein the catheter comprises an internal catheter, an inside external catheter, an outside external catheter, and a stabilizing tube that are sleeve-jointed in sequence; wherein states of the self-expanding prosthesis include: a compressed state, a semi-deployed state, and a deployed state; wherein the internal catheter is configured to accommodate the self-expanding prosthesis in the compressed state; wherein the inside external catheter is able to move with respect to the internal catheter, and comprises a distal end portion and a proximal end portion, the distal end portion configured to drive the self-expanding prosthesis to be compressed from the semi-deployed state to the compressed state; wherein the outside external catheter is able to move with respect to the internal catheter, and comprises a distal end assembly and a proximal end assembly, the distal end assembly configured to contain the self-expanding prosthesis to maintain the compressed state of the self-expanding prosthesis, wherein when the self-expanding prosthesis in the compressed state is delivered near a target position, the proximal end assembly of the outside external catheter is configured to be moved with respect to the proximal end portion of the inside external catheter, so that a state of the self-expanding prosthesis is changed from the compressed state to the semi-deployed state and wherein when the self-expanding prosthesis is delivered to the target position, the proximal end assembly of the outside external catheter is configured to be withdrawn with respect to the proximal end portion of the inside external catheter, so that the self-expanding prosthesis in the semi-deployed state is further deployed until the self-expanding prosthesis is in the deployed state; wherein the distal end assembly of the outside external catheter has a better flexibility than the distal end portion of the inside external catheter, while the distal end portion of the inside external catheter has a higher tensile property and a higher compressive property than the distal end assembly of the outside external catheter; and wherein the stabilizing tube and the internal catheter remain stationary relative to each other. wherein states of the self-expanding prosthesis include: a compressed state, a semi-deployed state, and a deployed state; wherein the internal catheter is configured to accommodate the self-expanding prosthesis in the compressed state; wherein the inside external catheter is able to move with respect to the internal catheter, and comprises a distal end portion and a proximal end portion, the distal end portion configured to drive the self-expanding prosthesis to be compressed from the semi-deployed state to the compressed state; wherein the outside external catheter is able to move with respect to the internal catheter, and comprises a distal end assembly and a proximal end assembly, the distal end assembly configured to contain the self-expanding prosthesis to maintain the compressed state of the self-expanding prosthesis, wherein when the self-expanding prosthesis in the compressed state is delivered near a target position, the proximal end assembly of the outside external catheter is configured to be moved with respect to the proximal end portion of the inside external catheter, so that a state of the self-expanding prosthesis is changed from the compressed state to the semi-deployed state and wherein when the self-expanding prosthesis is delivered to the target position, the proximal end assembly of the outside external catheter is configured to be withdrawn with respect to the proximal end portion of the inside external catheter, so that the self-expanding prosthesis in the semi-deployed state is further deployed until the self-expanding prosthesis is in the deployed state; wherein the distal end assembly of the outside external catheter has a better flexibility than the distal end portion of the inside external catheter, while the distal end portion of the inside external catheter has a higher tensile property and a higher compressive property than the distal end assembly of the outside external catheter; and wherein the stabilizing tube and the internal catheter remain stationary relative to each other.