mhurhangee/ep-ind-claims huggingface dataset:
A process for recovery of alkylene oxide comprising: introducing a feed stream containing alkylene oxide to a stripping section of an alkylene oxide recovery column, wherein the alkylene oxide recovery column comprises the stripping section and a reabsorption region (232, 234); stripping alkylene oxide from the feed stream to form a first gaseous portion in the stripping section, wherein the first gaseous portion flows from the stripping section to the reabsorption region (232, 234) of the alkylene oxide recovery column, and wherein the reabsorption region further comprises a first reabsorption section and a second reabsorption section; partially condensing in the alkylene oxide recovery column the first gaseous portion into a liquid reflux stream and an alkylene oxide rich vapor stream, wherein the liquid reflux stream is in physical communication with the stripping section; reabsorbing a first fraction of the alkylene oxide rich vapor stream in a first water stream to form a first aqueous solution in the first reabsorption section, wherein the first reabsorption section further comprises a first take-off to remove the first aqueous solution from the first reabsorption section; and reabsorbing a second fraction of the alkylene oxide rich vapor stream in a second water stream to form a second aqueous solution in the second reabsorption section, wherein the second reabsorption section further comprises a second take-off to remove the second aqueous solution from the second reabsorption section. introducing a feed stream containing alkylene oxide to a stripping section of an alkylene oxide recovery column, wherein the alkylene oxide recovery column comprises the stripping section and a reabsorption region (232, 234); stripping alkylene oxide from the feed stream to form a first gaseous portion in the stripping section, wherein the first gaseous portion flows from the stripping section to the reabsorption region (232, 234) of the alkylene oxide recovery column, and wherein the reabsorption region further comprises a first reabsorption section and a second reabsorption section; partially condensing in the alkylene oxide recovery column the first gaseous portion into a liquid reflux stream and an alkylene oxide rich vapor stream, wherein the liquid reflux stream is in physical communication with the stripping section; reabsorbing a first fraction of the alkylene oxide rich vapor stream in a first water stream to form a first aqueous solution in the first reabsorption section, wherein the first reabsorption section further comprises a first take-off to remove the first aqueous solution from the first reabsorption section; and reabsorbing a second fraction of the alkylene oxide rich vapor stream in a second water stream to form a second aqueous solution in the second reabsorption section, wherein the second reabsorption section further comprises a second take-off to remove the second aqueous solution from the second reabsorption section.
A method for conjugating a peptide of interest to the surface of a genetically engineered red blood cell, the method comprising: providing the genetically engineered red blood cell comprising a sortaggable surface fusion protein, wherein the sortaggable surface fusion protein comprises a type I red blood cell transmembrane protein and a peptide, and contacting the red blood cell with the peptide of interest in the presence of a sortase, wherein the N-terminus of the sortaggable surface fusion protein is exposed to the extracellular or luminal space, the peptide is either oligoglycine or oligoalanine fused to the N-terminus of the type I red blood cell transmembrane protein, and the peptide of interest comprises a sortase recognition motif; and wherein the sortase conjugates the peptide of interest to the sortaggable surface fusion protein, thereby conjugating the peptide of interest to the surface of the genetically engineered red blood cell. providing the genetically engineered red blood cell comprising a sortaggable surface fusion protein, wherein the sortaggable surface fusion protein comprises a type I red blood cell transmembrane protein and a peptide, and contacting the red blood cell with the peptide of interest in the presence of a sortase, wherein the N-terminus of the sortaggable surface fusion protein is exposed to the extracellular or luminal space, the peptide is either oligoglycine or oligoalanine fused to the N-terminus of the type I red blood cell transmembrane protein, and the peptide of interest comprises a sortase recognition motif; and wherein the sortase conjugates the peptide of interest to the sortaggable surface fusion protein, thereby conjugating the peptide of interest to the surface of the genetically engineered red blood cell.
A method, performed by a first radio access network, RAN, node for handling dual connectivity, DC, in redundancy transmission in a wireless communications network, wherein a first protocol data unit, PDU, session and/or quality of service, QoS, flow is established from a User Equipment, UE, to a Core Network, CN, via the first RAN node, the method comprising: - determining to set up a second PDU session and/or QoS flow between the UE and the CN via a second RAN node, the method being characterized by further comprising: - sending, to the second RAN node, a request for setup of the second PDU session and/or QoS flow, wherein the request comprises an indication that the second PDU session and/or QoS flow are setup for redundancy transmission. - determining to set up a second PDU session and/or QoS flow between the UE and the CN via a second RAN node, - sending, to the second RAN node, a request for setup of the second PDU session and/or QoS flow, wherein the request comprises an indication that the second PDU session and/or QoS flow are setup for redundancy transmission.
A method for transmitting data using the collaborative multiple input multiple output, MIMO, beamforming, characterized by comprising: selecting an MIMO mode in accordance with channel quality information, CQI, wherein the step of selecting the MIMO mode in accordance with the CQI comprises: selecting one MIMO mode from a plurality of predetermined MIMO modes in accordance with the CQI, wherein the plurality of predetermined MIMO modes comprise: a space multiplexing mode of the collaborative MIMO beamforming, a space diversity mode of the collaborative MIMO beamforming and a single transmitting end MIMO mode; performing MIMO encoding on a data stream in accordance with the selected MIMO mode, and distributing the encoded data stream to a plurality of transmitting ends which are mutual collaborative; and transmitting, by the plurality of transmitting ends, the encoded data stream. selecting an MIMO mode in accordance with channel quality information, CQI, wherein the step of selecting the MIMO mode in accordance with the CQI comprises: selecting one MIMO mode from a plurality of predetermined MIMO modes in accordance with the CQI, wherein the plurality of predetermined MIMO modes comprise: a space multiplexing mode of the collaborative MIMO beamforming, a space diversity mode of the collaborative MIMO beamforming and a single transmitting end MIMO mode; performing MIMO encoding on a data stream in accordance with the selected MIMO mode, and distributing the encoded data stream to a plurality of transmitting ends which are mutual collaborative; and transmitting, by the plurality of transmitting ends, the encoded data stream. selecting one MIMO mode from a plurality of predetermined MIMO modes in accordance with the CQI, wherein the plurality of predetermined MIMO modes comprise: a space multiplexing mode of the collaborative MIMO beamforming, a space diversity mode of the collaborative MIMO beamforming and a single transmitting end MIMO mode; performing MIMO encoding on a data stream in accordance with the selected MIMO mode, and distributing the encoded data stream to a plurality of transmitting ends which are mutual collaborative; and transmitting, by the plurality of transmitting ends, the encoded data stream.
A method performed by a base station supporting an Early Data Transmission, EDT, the method comprising: receiving, by the base station and from a Mobility Management Entity, MME, a first non-access-stratum, NAS, message, that comprises (i) downlink data for transmission by the base station to a wireless device and (ii) an indication related to the EDT; and based on the received indication related to the EDT in the first NAS message from the MME: determining-that there is no further downlink data, aside from the downlink data in the first NAS message. receiving, by the base station and from a Mobility Management Entity, MME, a first non-access-stratum, NAS, message, that comprises (i) downlink data for transmission by the base station to a wireless device and (ii) an indication related to the EDT; and based on the received indication related to the EDT in the first NAS message from the MME: determining-that there is no further downlink data, aside from the downlink data in the first NAS message.
An armrest assembly (101, 1) comprising: a base structure; an upper structure (25, 2) that has an upper surface providing an armrest, the upper structure (25, 2) being movable with respect to the base structure between an upper position and a lower position; an actuator (138, 38) for controlling movement of said upper structure (25, 2) relative to said base structure; and a locking device operable to lock said upper structure (25, 2) with respect to said base structure in at least one of said adoptable positions, said locking device including locking elements that inter-engage mechanically when said locking device locks said upper structure (25, 2) with respect to said base structure, characterised in that said actuator (138, 38) is operable between a locked state in which said actuator (138, 38) is locked to prevent movement of said upper structure (25, 2) with respect to said base structure, and an unlocked state in which said actuator (138, 38) is unlocked to facilitate movement of said upper structure (25, 2) with respect to said base structure, said armrest assembly (101, 1) further including at least one operating mechanism coupled to said actuator (138, 38) and to said locking device and being operable by a user to operate said actuator (138, 38) between its locked and unlocked states and to operate said locking device between its locked and unlocked states.
A method performed by an apparatus said method comprising: - obtaining or holding available positioning data collection condition information representing one or more positioning data collection conditions for collecting positioning data for updating and/or generating a positioning map; - obtaining or holding available historical sensor information representing one or more behavioral and/or environmental patterns that were detected by one or more sensors (204, 206, 207) of a mobile device; the method being characterised in that it further comprises: - determining or holding available mapping information representing, for each of said behavioral and/or environmental patterns, whether or not at least one of said one or more positioning data collection conditions was met after said respective behavioral and/or environmental pattern had been detected by said sensors (204, 206, 207) of said mobile device; - obtaining current sensor information representing a behavioral and/or environmental pattern that is currently detected by said one or more sensors (204, 206, 207) of said mobile device; - determining, at least partially based on said current sensor information and said mapping information, whether positioning data should be collected by said mobile device for updating and/or generating the positioning map; - if it is determined that positioning data should be collected by said mobile device for updating and/or generating the positioning map, collecting or triggering collecting positioning data by said mobile device for updating and/or generating the positioning map, - obtaining or holding available positioning data collection condition information representing one or more positioning data collection conditions for collecting positioning data for updating and/or generating a positioning map; - obtaining or holding available historical sensor information representing one or more behavioral and/or environmental patterns that were detected by one or more sensors (204, 206, 207) of a mobile device; - determining or holding available mapping information representing, for each of said behavioral and/or environmental patterns, whether or not at least one of said one or more positioning data collection conditions was met after said respective behavioral and/or environmental pattern had been detected by said sensors (204, 206, 207) of said mobile device; - obtaining current sensor information representing a behavioral and/or environmental pattern that is currently detected by said one or more sensors (204, 206, 207) of said mobile device; - determining, at least partially based on said current sensor information and said mapping information, whether positioning data should be collected by said mobile device for updating and/or generating the positioning map; - if it is determined that positioning data should be collected by said mobile device for updating and/or generating the positioning map, collecting or triggering collecting positioning data by said mobile device for updating and/or generating the positioning map,
A bearing assembly, comprising: a first plurality of superhard bearing elements distributed about an axis, each of the first plurality of superhard bearing elements having a substrate bonded to a superhard table comprising a superhard material including a superhard bearing surface; and a support ring structure coupled to the first plurality of superhard bearing elements; characterised in that the superhard material of at least some of the first plurality of superhard bearing elements exhibits a maximum thickness that is greater than 7,62 mm (0.3 inch). a first plurality of superhard bearing elements distributed about an axis, each of the first plurality of superhard bearing elements having a substrate bonded to a superhard table comprising a superhard material including a superhard bearing surface; and a support ring structure coupled to the first plurality of superhard bearing elements; characterised in that the superhard material of at least some of the first plurality of superhard bearing elements exhibits a maximum thickness that is greater than 7,62 mm (0.3 inch).
An isolated antibody, or an antigen-binding fragment thereof, that neutralizes infection of a group 1 subtype and a group 2 subtype of influenza A virus and comprises: (i) the heavy chain CDR1, CDR2 and CDR3 sequences as set forth in SEQ ID NOs: 1, 41 and 43, respectively, or as set forth in SEQ ID NOs: 1, 41 and 42, respectively; and (ii) the light chain CDR1, CDR2, and CDR3 sequences as set forth in SEQ ID NOs: 4, 5 and 6, respectively, or as set forth in SEQ ID NOs: 44, 5 and 6, respectively, wherein the antibody, or antigen-binding fragment thereof, is produced in transfected cells at titers of at least 3 fold higher than the titer at which FI6 variant 2 is produced.
A compound which is represented by the following formula II or is a pharmaceutically acceptable salt thereof for use in the treatment of patients with cytokine release syndrome toxicity resistant to tocilizumab administration or for use in the prevention, treatment or amelioration of at least one selected from the group consisting of autoimmune-related adverse events, macrophage activation syndrome, hemophagocytic lymphohistiocytosis and Langerhans cell histiocytosis wherein the autoimmune disease-related adverse events are a group of adverse events associated with immune checkpoint inhibitors whose administration results in excessive activation of overall immunity and thereby induces self-attack to cause various symptoms of autoimmune diseases, wherein the symptoms are selected from interstitial lung disease, colitis, hypothyroidism, hepatopathy, exanthema, hypophysitis, diabetes, renal dysfunction, peripheral neuropathy and myasthenia gravis;
Sleeve yoke comprising fixing surfaces that provide fixing of the sleeve yoke to the broaching bench for the process of cutting spline profiles in the inner section of the sleeve yoke, characterised in that, it comprises heights formed on the ear lugs of the said sleeve yoke and the fixing surfaces formed on these heights.
A surgical instrument: a first member extending between a proximal end and a distal end configured for fixation with tissue; a second member defining a longitudinal passageway and being connected with a navigation component such that the distal end is disposable with the passageway at a selected distance from the navigation component, the navigation component being positioned relative to a sensor to communicate a signal representative of an axial orientation of the first member; a third member extending between a proximal end and a distal end, the third member being mountable with the first member along the orientation such that the distal end of the third member is engageable with the tissue; and a fourth member connectable with the first member and configured to adjust a depth of the first member, wherein the fourth member includes a part configured to adjust a depth of the first member relative to tissue and the navigation component. a first member extending between a proximal end and a distal end configured for fixation with tissue; a second member defining a longitudinal passageway and being connected with a navigation component such that the distal end is disposable with the passageway at a selected distance from the navigation component, the navigation component being positioned relative to a sensor to communicate a signal representative of an axial orientation of the first member; a third member extending between a proximal end and a distal end, the third member being mountable with the first member along the orientation such that the distal end of the third member is engageable with the tissue; and a fourth member connectable with the first member and configured to adjust a depth of the first member, wherein the fourth member includes a part configured to adjust a depth of the first member relative to tissue and the navigation component.
A blood pump assembly comprising: a blood pump housing component; at least one input port and at least one outlet port; and a sensor coupled to the blood pump housing component, the sensor including a sensor membrane configured to deflect in response to a change in a blood parameter, the sensor being coupled to a transmission fiber; wherein the blood pump assembly includes a shield that covers at least a portion of the sensor membrane to protect the sensor from physical damage, and a sensor visor to protect the sensor from physical damage, the sensor visor extending in a distal direction beyond the sensor membrane. a blood pump housing component; at least one input port and at least one outlet port; and a sensor coupled to the blood pump housing component, the sensor including a sensor membrane configured to deflect in response to a change in a blood parameter, the sensor being coupled to a transmission fiber; wherein the blood pump assembly includes a shield that covers at least a portion of the sensor membrane to protect the sensor from physical damage, and a sensor visor to protect the sensor from physical damage, the sensor visor extending in a distal direction beyond the sensor membrane.
Compressor installation with a compressor element and a combustion engine, the compressor installation being provided with a transmission between a combustion engine with a crankshaft and said compressor element with driven shaft, whereby this transmission comprises a housing and at least one driven gear and driveshaft with a drive gear characterised in that the driveshaft of the transmission is connected to the crankshaft of the combustion engine by means of a rigid coupling, and that the distance between the driveshaft and the driven shaft is greater than the sum of the radii (B, C) of the pitch circles of the drive gear and the driven gear.
A method for preparing a pharmaceutical composition the method comprising: (i) providing a first combination comprising: (a) a compound: or a pharmaceutically acceptable salt thereof; (b) a low chloride cyclodextrin ("CD"), that is a chloride-containing cyclodextrin having less than or equal to 0.05% w/w sodium chloride, or if a chloride source(s) other than or in addition to sodium chloride is/are present, a chloride-containing cyclodextrin having a chloride ion content that is less than or equal to the amount of chloride that would be present in a cyclodextrin having 0.05% w/w sodium chloride, and (c) water; wherein the first combination is heterogeneous and the compound or salt has a low solubility in the first combination; and (ii) contacting the first combination with an acid to form a second combination, wherein the compound is more soluble in the second combination than in the first combination and the acid is selected from lactic acid, acetic acid, formic acid, citric acid, oxalic acid, uric acid, succinic acid, maleic acid, fumaric acid, benzoic acid, tartaric acid, bisulfate, and phosphoric acid or salts of phosphate, wherein the method is performed in the absence of hydrochloric acid. (i) providing a first combination comprising: (a) a compound: or a pharmaceutically acceptable salt thereof; (b) a low chloride cyclodextrin ("CD"), that is a chloride-containing cyclodextrin having less than or equal to 0.05% w/w sodium chloride, or if a chloride source(s) other than or in addition to sodium chloride is/are present, a chloride-containing cyclodextrin having a chloride ion content that is less than or equal to the amount of chloride that would be present in a cyclodextrin having 0.05% w/w sodium chloride, and (c) water; wherein the first combination is heterogeneous and the compound or salt has a low solubility in the first combination; and (a) a compound: or a pharmaceutically acceptable salt thereof; (b) a low chloride cyclodextrin ("CD"), that is a chloride-containing cyclodextrin having less than or equal to 0.05% w/w sodium chloride, or if a chloride source(s) other than or in addition to sodium chloride is/are present, a chloride-containing cyclodextrin having a chloride ion content that is less than or equal to the amount of chloride that would be present in a cyclodextrin having 0.05% w/w sodium chloride, and (c) water; wherein the first combination is heterogeneous and the compound or salt has a low solubility in the first combination; and (ii) contacting the first combination with an acid to form a second combination, wherein the compound is more soluble in the second combination than in the first combination and the acid is selected from lactic acid, acetic acid, formic acid, citric acid, oxalic acid, uric acid, succinic acid, maleic acid, fumaric acid, benzoic acid, tartaric acid, bisulfate, and phosphoric acid or salts of phosphate,