mhurhangee/ep-ind-claims huggingface dataset:
A modified factor VII (FVII) polypeptide, comprising: a heterologous Gla domain, or a sufficient portion thereof to effect phospholipid binding, whereby the modified FVII polypeptide exhibits increased phospholipid affinity or binding compared with an unmodified FVII polypeptide that does not contain the heterologous Gla domain, wherein: the sufficient portion contains 30 or more contiguous amino acids from the heterologous Gla domain; and the heterologous Gla domain is selected from among a Gla domain in Factor IX, Factor X, prothrombin, protein C, protein S, osteocalcin, Growth-arrest-specific protein 6 and protein Z; and one or more further amino acid modification(s) that increases resistance to antithrombin-III (AT-III), increases affinity for tissue factor, increases intrinsic activity, increases TF-dependent catalytic or coagulant activity, increases coagulant activity, alters the conformation of the polypeptide to alter zymogenicity, increases catalytic or coagulant activity by shifting the equilibrium between highly active and less active FVIIa conformations in favor of the highly active conformations, increases resistance to proteases, decreases glycosylation, increases glycosylation, reduces immunogenicity, increases stability, and/or facilitates chemical group linkage. a heterologous Gla domain, or a sufficient portion thereof to effect phospholipid binding, whereby the modified FVII polypeptide exhibits increased phospholipid affinity or binding compared with an unmodified FVII polypeptide that does not contain the heterologous Gla domain, wherein: the sufficient portion contains 30 or more contiguous amino acids from the heterologous Gla domain; and the heterologous Gla domain is selected from among a Gla domain in Factor IX, Factor X, prothrombin, protein C, protein S, osteocalcin, Growth-arrest-specific protein 6 and protein Z; and the sufficient portion contains 30 or more contiguous amino acids from the heterologous Gla domain; and the heterologous Gla domain is selected from among a Gla domain in Factor IX, Factor X, prothrombin, protein C, protein S, osteocalcin, Growth-arrest-specific protein 6 and protein Z; and one or more further amino acid modification(s) that increases resistance to antithrombin-III (AT-III), increases affinity for tissue factor, increases intrinsic activity, increases TF-dependent catalytic or coagulant activity, increases coagulant activity, alters the conformation of the polypeptide to alter zymogenicity, increases catalytic or coagulant activity by shifting the equilibrium between highly active and less active FVIIa conformations in favor of the highly active conformations, increases resistance to proteases, decreases glycosylation, increases glycosylation, reduces immunogenicity, increases stability, and/or facilitates chemical group linkage.
A reinforcement element for a diaphragm wall including a reinforcement cage which has a height defining a longitudinal direction, a width and a thickness (e), the reinforcement cage having a first end part and a second end part considered along its width as opposite to the first end part, the first and second end parts (18a, 18b) extending along the longitudinal direction of the reinforcement cage, the reinforcement element further including at least one seal-carrier provided with a mounting part for receiving at least one seal which is elongated, the seal-carrier being fixed to the first end part of the reinforcement cage and extending along the longitudinal direction of said reinforcement cage, the reinforcement element being characterized in that the seal-carrier has two flanges (30a, 30b) extending along the longitudinal direction and a bottom so as to define a housing for receiving the seal, at least a first part of which is surrounded by a sacrificial material, the mounting part including a longitudinal slot formed in the bottom to receive the seal.
A method of hydrothermal carbonization of a sludge, comprising the steps of: preheating the sludge to obtain a preheated sludge; mixing the preheated sludge with a wet-oxidized fraction to obtain a reaction mixture; subjecting the reaction mixture to hydrothermal carbonization in a reactor to obtain a HTC-treated sludge; separating a fraction from the HTC-treated sludge; and mixing the fraction with an oxidizing agent, such as oxygen gas, to obtain the wet-oxidized fraction, wherein the temperature of the fraction before the wet oxidation is at least 15 °C higher than the temperature of the preheated sludge. preheating the sludge to obtain a preheated sludge; mixing the preheated sludge with a wet-oxidized fraction to obtain a reaction mixture; subjecting the reaction mixture to hydrothermal carbonization in a reactor to obtain a HTC-treated sludge; separating a fraction from the HTC-treated sludge; and mixing the fraction with an oxidizing agent, such as oxygen gas, to obtain the wet-oxidized fraction,
Device for investigating the adhesion tendency of a test element to an artificial wound, comprising - a substrate, - a means for removing the test element from the substrate, where the distance travelled and the force expended on removal of the test element from the substrate can be measured, characterized in that - the substrate comprises an indentation which forms an artificial wound pocket and into which a connecting medium and the test element can be introduced, the connecting medium being intended essentially to contribute to adhering the test element to the substrate, - the indentation comprises a region having a structured surface and where the structured surface has a maximum roughness depth of 10 μm to 800 μm, measured according to DIN EN ISO 4287:1998 + AC:2008 + A1:2009 D and DIN EN ISO 4288:1997 D. - a substrate, - a means for removing the test element from the substrate, where the distance travelled and the force expended on removal of the test element from the substrate can be measured, characterized in that - the substrate comprises an indentation which forms an artificial wound pocket and into which a connecting medium and the test element can be introduced, the connecting medium being intended essentially to contribute to adhering the test element to the substrate, - the indentation comprises a region having a structured surface and
Injection section of an exhaust gas system for an internal combustion engine - with a channel for conveying an exhaust gas flow, - with an injector connection which is laterally arranged on the channel and to which an injector for introducing a fluid or a gas into the exhaust gas flow can be connected, - with an injection chamber which is formed in the channel in the area of the injector connection and which is delimited on the one hand by a perforated first dividing wall through which the exhaust gas flow passes and which is arranged in the channel upstream of the injector connection with regard to the exhaust gas flow, and on the other hand by a perforated second dividing wall through which the exhaust gas flow passes and which is arranged in the channel downstream of the injector connection with regard to the exhaust gas flow characterised in - that a perforation of the first dividing wall is designed in such a way that when a flow passes through the first dividing wall within the injection chamber it produces at least two partial exhaust gas flows (20, 21), which create the two counter-rotating flow vortices (22, 23), - that the two partial exhaust gas flows (20, 21) separately flow proximally to a channel wall laterally delimiting the injection chamber and jointly flow distally to the channel wall. - with a channel for conveying an exhaust gas flow, - with an injector connection which is laterally arranged on the channel and to which an injector for introducing a fluid or a gas into the exhaust gas flow can be connected, - with an injection chamber which is formed in the channel in the area of the injector connection and which is delimited on the one hand by a perforated first dividing wall through which the exhaust gas flow passes and which is arranged in the channel upstream of the injector connection with regard to the exhaust gas flow, and on the other hand by a perforated second dividing wall through which the exhaust gas flow passes and which is arranged in the channel downstream of the injector connection with regard to the exhaust gas flow characterised in - that a perforation of the first dividing wall is designed in such a way that when a flow passes through the first dividing wall within the injection chamber it produces at least two partial exhaust gas flows (20, 21), which create the two counter-rotating flow vortices (22, 23), - that the two partial exhaust gas flows (20, 21) separately flow proximally to a channel wall laterally delimiting the injection chamber and jointly flow distally to the channel wall.
Structural element for thermal insulation between a load-bearing and a supported component, in particular between a building and a projecting external part, with an insulating body to be arranged between the two components, and with reinforcing elements in the form of at least pressure elements (5, 15), which in the installed state of the structural element, extend through the insulating body essentially horizontally to and transversely to the essentially horizontal longitudinal extension of the insulating body, and can be connected at least indirectly to both components (A, B), wherein the structural element has additional reinforcing elements in the form of elements transmitting tractive forces, and wherein support elements (6, 16) are assigned to the pressure elements (5, 15), which support elements are arranged relative to the structural element in the installed state at a different height level than the pressure elements, wherein in each case a pressure element (5, 15) and a support element (6, 16) are operatively connected to one another via a transverse force element (4, 14a, 14b), characterised in that the support elements (6, 16) are arranged below the traction elements and below a traction zone in relation to the structural element in the installed state.
A latex composition comprising a latex of a carboxyl group-containing conjugated diene rubber, a metal compound including a trivalent or higher metal, and at least one alcoholic hydroxyl group-containing compound selected from a saccharide, a sugar alcohol, a hydroxy acid, and a hydroxy acid salt, wherein the hydroxy acid salt is an alkali metal salt of hydroxy acid or alkali earth metal salt of hydroxy acid, and a content of the metal compound is 0.1 to 1.5 parts by weight, based on 100 parts by weight of the carboxyl group-containing conjugated diene rubber.
A rotor for being accommodated in a rotor chamber of a centrifuge, the rotor comprising: a rotor body configured to hold one or more samples and a rotor cover covering an opening portion of the rotor body; and characterised by: an inclined surface extending toward a radial outer side of an outer edge of an upper surface of the rotor cover and extending upward from the outer edge of the upper surface of the rotor cover is formed on the rotor body. a rotor body configured to hold one or more samples and a rotor cover covering an opening portion of the rotor body; and characterised by: an inclined surface extending toward a radial outer side of an outer edge of an upper surface of the rotor cover and extending upward from the outer edge of the upper surface of the rotor cover is formed on the rotor body.
A headset unit for a mobile telephone, the headset unit comprising: an ear-hook unit including a cartilage conduction vibration unit capable of making contact with an ear cartilage in a state where the ear-hook unit is hooked to an ear, and a microphone, wherein in the state where the ear-hook unit is hooked to the ear, the cartilage conduction vibration unit is arranged at a position in contact with a rear part of the outer side of the cartilage of a base of the ear, and the microphone is arranged in front of the ear, characterized in that the ear-hook unit includes a unit for performing short-range wireless communication with the mobile telephone, the ear-hook unit includes an incoming/outgoing-talk operation unit and a controller which is configured to control the microphone and the cartilage conduction vibration unit, the ear-hook unit has a front part, a rear part, an upper part, and a lower part, in the state where the ear-hook unit is hooked to the ear, the front part is located on a front side of the ear, the rear part is located on a rear side of the ear, the upper part is located on a top side of the ear, and the lower part is located on a bottom side of the ear, the front part is connected to the upper part, the upper part is connected to the rear part, the rear part is connected to the lower part, and the front part is separated from the lower part, and the front part, the rear part, the upper part, and the lower part are formed integrally, and the microphone is arranged in the front part and the cartilage conduction vibration unit is arranged in the rear part. an ear-hook unit including a cartilage conduction vibration unit capable of making contact with an ear cartilage in a state where the ear-hook unit is hooked to an ear, and a microphone, wherein in the state where the ear-hook unit is hooked to the ear, the cartilage conduction vibration unit is arranged at a position in contact with a rear part of the outer side of the cartilage of a base of the ear, and the microphone is arranged in front of the ear, characterized in that the ear-hook unit includes a unit for performing short-range wireless communication with the mobile telephone, the ear-hook unit includes an incoming/outgoing-talk operation unit and a controller which is configured to control the microphone and the cartilage conduction vibration unit, the ear-hook unit has a front part, a rear part, an upper part, and a lower part, in the state where the ear-hook unit is hooked to the ear, the front part is located on a front side of the ear, the rear part is located on a rear side of the ear, the upper part is located on a top side of the ear, and the lower part is located on a bottom side of the ear, the front part is connected to the upper part, the upper part is connected to the rear part, the rear part is connected to the lower part, and the front part is separated from the lower part, and the front part, the rear part, the upper part, and the lower part are formed integrally, and the microphone is arranged in the front part and the cartilage conduction vibration unit is arranged in the rear part.
Multimedia and multichannel information system for an interactive distribution of at least one real-time video input of a live event taking place in an auditorium, the system comprising: a central unit; and a plurality of remote units, wherein each remote unit of the plurality is installed on an armchair or a wall of the auditorium, wherein each remote unit is connected to the central unit by means of a bi-directional transmission network for interactive communications between the remote units and the central unit, wherein each remote unit is provided with at least an interface and with audio/video, data and graphics accelerators disposed on a multimedia microprocessor housed in each of said remote units, and wherein each remote unit is equipped with a touch screen display and is operable to display the at least one real-time video input of the live event taking place in the auditorium, wherein each remote unit has a configurable univocal address and comprises a connector for an external microphone. a central unit; and a plurality of remote units, wherein each remote unit of the plurality is installed on an armchair or a wall of the auditorium, wherein each remote unit is connected to the central unit by means of a bi-directional transmission network for interactive communications between the remote units and the central unit, wherein each remote unit is provided with at least an interface and with audio/video, data and graphics accelerators disposed on a multimedia microprocessor housed in each of said remote units, and wherein each remote unit is equipped with a touch screen display and is operable to display the at least one real-time video input of the live event taking place in the auditorium, wherein each remote unit has a configurable univocal address and comprises a connector for an external microphone.
Method to control a multi-terminal HVDC power transmission network comprising at least two transmission lines (12, 14, 16, 18, 20), where at least one of the transmission lines is a line having a length of approximately or more than 500 km, wherein the DC voltage level of the transmission lines (12, 14, 16, 18, 20) is maintained to be within a predefined voltage range by controlling an active voltage source device, which is connected in series to one of the transmission lines, to inject a DC voltage in series with the one transmission line where the device is arranged to be power supplied from the transmission line characterized in that the device comprises a first converter in series connection with the one transmission line and a second converter in shunt connection with the one transmission line, the method comprising the steps of converting, by the second converter working as an inverter, DC power from the one transmission line into AC power, supplying, by said second converter, the first converter with said AC power, and providing, by the first converter working as a rectifier, the DC voltage to be injected into the one transmission line.
In a nanoimprint lithography system, a method comprising: providing a template (18; 18a) in contact with a formed patterned layer on a substrate (12; 12a), the template and the substrate having lateral strains (d t and d b) associated therewith, respectively, when subjected to a separation force; adjusting the lateral strain of the template (d t) or the substrate (d b) or both by adjusting the back pressure applied to the template (18; 18a) and/or substrate (12; 12a) such that the ratio of the lateral strains (d t /d b) is approximately 1 when the template (18; 18a) and substrate (12; 12a) are subjected to the separation force; and applying the separation force to separate the template (18; 18a) from the substrate (12; 12a). providing a template (18; 18a) in contact with a formed patterned layer on a substrate (12; 12a), the template and the substrate having lateral strains (d t and d b) associated therewith, respectively, when subjected to a separation force; adjusting the lateral strain of the template (d t) or the substrate (d b) or both by adjusting the back pressure applied to the template (18; 18a) and/or substrate (12; 12a) such that the ratio of the lateral strains (d t /d b) is approximately 1 when the template (18; 18a) and substrate (12; 12a) are subjected to the separation force; and applying the separation force to separate the template (18; 18a) from the substrate (12; 12a).
A method for information transmission, comprising sending, by a network device, first indication information, the first indication information being used to indicate a reserved resource and being sent according to a configuration of the first indication information, wherein the first indication information belongs to a first message, the first message carries an indication field, the indication field indicates that the first message is used to carry the first indication information when a value of the indication field is a first value, the indication field indicates that the first message is used to carry an uplink or downlink grant when the value of the indication field is a second value.
Apparatus for detecting mechanical features of metal materials, said apparatus comprising: - an indenter adapted to be pushed against a sample material and to penetrate in said material for a depth (h) that is correlated to its hardness; - a means for generating a measured force; - a means for amplifying (3,4) said force produced by said means for generating and for causing said indenter to exert a contact force to said sample, said means for amplifying (3,4) said force being of hydraulic type; - a means for measuring in successive instants (t1, t2, t3,...ti, tN) the instant values of said contact force of said indenter on said sample; - a means for measuring (50a,50b,50c) the penetration (h) of said indenter in said sample; - a means for analysing (65,60) couples of data, each of said data generated by associating, for each instant of detection, a measured value of said contact force with a relative measured value of penetration (h); characterised in that said means for measuring said penetration (h) in said sample provides at least three position sensors (50a,50b,50c) arranged at 120° from one another along a circumference concentric to said indenter, in such a way that a measure is obtained relative to the plane defined by the circumference along which the three sensors are arranged. - an indenter adapted to be pushed against a sample material and to penetrate in said material for a depth (h) that is correlated to its hardness; - a means for generating a measured force; - a means for amplifying (3,4) said force produced by said means for generating and for causing said indenter to exert a contact force to said sample, said means for amplifying (3,4) said force being of hydraulic type; - a means for measuring in successive instants (t1, t2, t3,...ti, tN) the instant values of said contact force of said indenter on said sample; - a means for measuring (50a,50b,50c) the penetration (h) of said indenter in said sample; - a means for analysing (65,60) couples of data, each of said data generated by associating, for each instant of detection, a measured value of said contact force with a relative measured value of penetration (h);
Low-sulphate aerated concrete, prepared from water and the following constituents, each specified as a percentage by weight of the dry material in the mixture: 25 to 65 % quartz flour, 5 to 30 % returned aerated concrete, 5 to 25 % burnt lime with a CaO content of 90 to 99 per cent by weight, 0.05 to 0.4 % aluminium component, characterised in that the aerated concrete further contains the following constituents, likewise each specified as a percentage by weight of the dry material in the mixture: 0 to 40 % cement, 0 to 15 % aerated concrete, ground, 0 to 5 % of a sulphate carrier such as anhydrite or gypsum, 0 to 15 % calcined clay, referred to as CC, and/or 0 to 15 % amorphous clay, referred to as AC, where the total of CC and AC comes to at least 1.5 %, and which is of a grey, brown or grey-brown colour and a leaching behaviour that results in a sulphate concentration of maximum 500 mg/l sulphate in the eluate and a total hygric shrinkage of 0.4 mm/m or less. 25 to 65 % quartz flour, 5 to 30 % returned aerated concrete, 5 to 25 % burnt lime with a CaO content of 90 to 99 per cent by weight, 0.05 to 0.4 % aluminium component, 0 to 40 % cement, 0 to 15 % aerated concrete, ground, 0 to 5 % of a sulphate carrier such as anhydrite or gypsum, 0 to 15 % calcined clay, referred to as CC, and/or 0 to 15 % amorphous clay, referred to as AC,