mhurhangee/ep-ind-claims huggingface dataset:
Method for the grinding machining, carried out in a single clamping, of a machine component which is driven in rotation about its longitudinal axis, which is clamped at its two axial ends (3, 5) and has an internal recess on at least one of its ends, which is ground by means of an internal grinding wheel, the machine component being held in a single clamping between a workpiece headstock and a tailstock rotarily driven and ground on its outer contour by means of at least one grinding wheel, wherein a) the machine component is held centred on the tailstock by means of a revolving or rotary driven tailstock hollow sleeve with a hollow tip at the end region of the internal recess; b) the internal grinding wheel engages through the tailstock hollow sleeve during grinding of the internal recess, and c) the clamping on the workpiece headstock is carried out with a centrically clamping chuck or with a chuck with compensating clamping jaws and a centring point (13, 20.1) engaging in the end face of the machine component. a) the machine component is held centred on the tailstock by means of a revolving or rotary driven tailstock hollow sleeve with a hollow tip at the end region of the internal recess; b) the internal grinding wheel engages through the tailstock hollow sleeve during grinding of the internal recess, and c) the clamping on the workpiece headstock is carried out with a centrically clamping chuck or with a chuck with compensating clamping jaws and a centring point (13, 20.1) engaging in the end face of the machine component.
Use of a population of metallic nanoparticles to prepare a pharmaceutical composition for use in a method of perturbing, altering or destroying target mammalian cells in vivo, selected in the group consisting of benign cells, pre-malignant cells and malignant cells, when said cells are exposed to ionizing radiations, wherein the nanoparticles are made of a metal having an atomic number of at least 25 selected from gold (Au), silver (Ag), platinum (Pt), palladium (Pd), tin (Sn), tantalum (Ta), ytterbium (Yb), Zirconium (Zr), hafnium (Hf), terbium (Tb), thulium (Tm), cerium (Ce), dysprosium (Dy), erbium (Er), europium (Eu), holmium (Ho), Iron (Fe), lanthanum (La), neonydium (Nd) and praseodymium (Pr), the metallic nanoparticle is essentially spherical in shape and the mean largest size of the metallic core of a nanoparticle of the population is between about 80 and 105 nm, and wherein the metallic nanoparticle is covered with a biocompatible coating.
A method for localizing an RFID transponder, comprising: generating a plurality of measurement signals based on a magnetic field measured by a plurality of sensors (110-1, 110-2,..., 110-5); determining a respective degree of correlation for each of the plurality of measurement signals with a reference signal as a measure for the strength of the contribution to the magnetic field originating from the RFID transponder at the position of the respective sensor by means of respective cross-correlation of each of the plurality of measurement signals with the reference signal, the reference signal being based on a data sequence associated with the RFID transponder; and determining a position of the RFID transponder based on the degrees of correlation of the plurality of measurement signals. generating a plurality of measurement signals based on a magnetic field measured by a plurality of sensors (110-1, 110-2,..., 110-5); determining a respective degree of correlation for each of the plurality of measurement signals with a reference signal as a measure for the strength of the contribution to the magnetic field originating from the RFID transponder at the position of the respective sensor by means of respective cross-correlation of each of the plurality of measurement signals with the reference signal, the reference signal being based on a data sequence associated with the RFID transponder; and determining a position of the RFID transponder based on the degrees of correlation of the plurality of measurement signals.
A fuel cell system comprising: a fuel cell module adapted to perform power generation by an electrochemical reaction and discharge an exhaust combustion gas that is generated by the power generation; a water storage tank storing water that serves as a storage water; a storage water circulation line at which the storage water circulates; a storage water circulation pump provided at the storage water circulation line and driven by an electric motor (32a1); a heat exchanger adapted to perform a heat exchange between the exhaust combustion gas and the storage water; and an air bubble detection portion adapted to detect a generation of air bubbles at the storage water circulation line; and a control unit adapted to control the storage water circulation pump, characterized in that the control unit is adapted to stop the storage water circulation pump operating for a predetermined time period in response to an air bubble detection signal generated by the air bubble detection portion and to resume the operation of the storage water circulation pump, wherein the predetermined time period is a time period in which air bubbles that are stirred are raised by buoyancy to be collected at an upper portion of an inside of the storage water circulation pump which results in a mass of air bubbles. a fuel cell module adapted to perform power generation by an electrochemical reaction and discharge an exhaust combustion gas that is generated by the power generation; a water storage tank storing water that serves as a storage water; a storage water circulation line at which the storage water circulates; a storage water circulation pump provided at the storage water circulation line and driven by an electric motor (32a1); a heat exchanger adapted to perform a heat exchange between the exhaust combustion gas and the storage water; and an air bubble detection portion adapted to detect a generation of air bubbles at the storage water circulation line; and a control unit adapted to control the storage water circulation pump, characterized in that the control unit is adapted to stop the storage water circulation pump operating for a predetermined time period in response to an air bubble detection signal generated by the air bubble detection portion and to resume the operation of the storage water circulation pump, wherein the predetermined time period is a time period in which air bubbles that are stirred are raised by buoyancy to be collected at an upper portion of an inside of the storage water circulation pump which results in a mass of air bubbles.
A surface treatment system, comprising: an induction heater arranged and disposed to heat a component to form a heated surface while in an induction treatment mode, the induction heater comprising one or more induction coils; a nozzle arrangement positioned to apply a fluid to the heated surface of the component at a pressure above a cavitation pressure of the fluid to form a processed surface while in a fluid application mode, wherein the processed surface includes compressive residual stress; and characterized in that the induction heater includes a fluid passage having an inlet and an outlet, wherein the fluid passage is configured to transport fluid from the inlet to the nozzle arrangement during a fluid application mode and to transport fluid from the inlet to the outlet during an induction treatment mode so as to cool the interior of the one or more induction coils. an induction heater arranged and disposed to heat a component to form a heated surface while in an induction treatment mode, the induction heater comprising one or more induction coils; a nozzle arrangement positioned to apply a fluid to the heated surface of the component at a pressure above a cavitation pressure of the fluid to form a processed surface while in a fluid application mode, wherein the processed surface includes compressive residual stress; and characterized in that the induction heater includes a fluid passage having an inlet and an outlet, wherein the fluid passage is configured to transport fluid from the inlet to the nozzle arrangement during a fluid application mode and to transport fluid from the inlet to the outlet during an induction treatment mode so as to cool the interior of the one or more induction coils. the induction heater includes a fluid passage having an inlet and an outlet, wherein the fluid passage is configured to transport fluid from the inlet to the nozzle arrangement during a fluid application mode and to transport fluid from the inlet to the outlet during an induction treatment mode so as to cool the interior of the one or more induction coils.
A method for determining mucosa alterations in sample employing an array for at least two different interacting substances, at least one of which comprises one or more indicator molecules selected from pH indicator dye, ionochromic dye and tissue stain interacting with the sample, wherein the interacting is specific, the method comprising following steps: a) introducing a solution comprising the sample to the array, wherein the solution or the array comprises a reagent comprising a lanthanide ion, to form at least two admixtures, b) exciting the at least two admixtures at a first excitation wavelength, and detecting a signal deriving from the lanthanide ion at a first emission wavelength by using luminescent measurement to obtain a fingerprint of the sample; c) determining the presence or absence of the mucosa alterations by comparing the fingerprint of the sample with i) at least one fingerprint of an array obtained from a sample with mucosa alterations, and/or ii) at least one fingerprint of an array obtained from a sample of with no mucosa alterations, in proviso that the reagent comprising a lanthanide ion does not comprise any sample specific recognition elements or any indicator molecule specific recognition elements. a) introducing a solution comprising the sample to the array, wherein the solution or the array comprises a reagent comprising a lanthanide ion, to form at least two admixtures, b) exciting the at least two admixtures at a first excitation wavelength, and detecting a signal deriving from the lanthanide ion at a first emission wavelength by using luminescent measurement to obtain a fingerprint of the sample; c) determining the presence or absence of the mucosa alterations by comparing the fingerprint of the sample with i) at least one fingerprint of an array obtained from a sample with mucosa alterations, and/or ii) at least one fingerprint of an array obtained from a sample of with no mucosa alterations, in proviso that the reagent comprising a lanthanide ion does not comprise any sample specific recognition elements or any indicator molecule specific recognition elements. i) at least one fingerprint of an array obtained from a sample with mucosa alterations, and/or ii) at least one fingerprint of an array obtained from a sample of with no mucosa alterations,
An actuator comprising: a guide that extends in one direction; and a slider that is movable in an axial direction with respect to the guide, wherein at least one part of one surface of the guide is open, wherein the slider has an air pad that ejects compression gas, and at least two air servo chambers for driving the slider, and is configured so as to be floated with respect to the guide and guided by the guide, characterised in that the two air servo chambers are formed so as to face an inner surface and another inner surface of the guide that face each other with the slider interposed therebetween. a guide that extends in one direction; and a slider that is movable in an axial direction with respect to the guide, wherein at least one part of one surface of the guide is open, wherein the slider has an air pad that ejects compression gas, and at least two air servo chambers for driving the slider, and is configured so as to be floated with respect to the guide and guided by the guide,
A drive system for energizing a device, comprising: a bellows (104, 104', 1103) actuated drive, the bellows actuated drive being configured to provide linear forward and backward movement by fluid (107, 1113) expansion and contraction of a fluid within a reservoir according to a temperature differential, and the reservoir being in fluid communication with the bellows, characterized in that the drive system comprises a buckling diaphragm in fluid communication with the reservoir, the diaphragm being sized and dimensioned to provide the bellows actuated drive with an extension limitation.
A monoclonal antibody or antigen-binding fragment thereof comprising: a V H amino acid sequence of SEQ ID NO:2 and a V L amino acid sequence of SEQ ID NO:4; or a V H amino acid sequence of SEQ ID NO:6 and a V L amino acid sequence of SEQ ID NO:8. a V H amino acid sequence of SEQ ID NO:2 and a V L amino acid sequence of SEQ ID NO:4; or a V H amino acid sequence of SEQ ID NO:6 and a V L amino acid sequence of SEQ ID NO:8.
A method for monitoring disease progression in a patient having mesenchymal stem cell therapy for an inflammatory condition, the method comprising determining the level of a biomarker MIF in at least a first and a second biological sample from said patient, wherein a change in the level of said biomarker in said second compared to said first biological sample is indicative of disease progression, wherein (i) an increase in the detectable level of said biomarker in a second compared to a first biological sample is indicative of pathological progression, or deterioration, of the inflammatory condition; or (ii) a decrease in the detectable level of said biomarker in a second compared to a first biological sample is indicative of stabilisation of or improvement of the inflammatory condition, and wherein said therapy comprises (i) a course of treatment comprising multiple doses over time of a cell suspension comprising mesenchymal stem cells (MSCs); or (ii) a course of treatment comprising multiple doses over time of an autologous adipose tissue-derived cell suspension comprising adipose tissue-derived non-adipocyte cells, wherein a first dose comprises a portion of a freshly prepared cell suspension and a subsequent dose or doses comprise a portion of said cell suspension that has been stored frozen; or (iii) a course of treatment comprising multiple doses over time of an allogeneic adipose tissue-derived cell suspension comprising adipose tissue-derived non-adipocyte cells, wherein all doses comprise a cell suspension that has been stored frozen. (i) a course of treatment comprising multiple doses over time of a cell suspension comprising mesenchymal stem cells (MSCs); or (ii) a course of treatment comprising multiple doses over time of an autologous adipose tissue-derived cell suspension comprising adipose tissue-derived non-adipocyte cells, wherein a first dose comprises a portion of a freshly prepared cell suspension and a subsequent dose or doses comprise a portion of said cell suspension that has been stored frozen; or (iii) a course of treatment comprising multiple doses over time of an allogeneic adipose tissue-derived cell suspension comprising adipose tissue-derived non-adipocyte cells, wherein all doses comprise a cell suspension that has been stored frozen.
A catalytic support for catalysis processes comprising a main body made of plastic material, at least one conduit made in said main body, said conduit having an inlet portion made on a first surface of said main body and an outlet portion made on a second surface of said main body, said first surface being opposite said second surface characterised in that said main body comprises a plurality of layers at least partially superposed and mutually adherent in such a way as to form said main body, said layers of said main body forming a plurality of recesses at the intersections and superposition of said layers, said recesses being configured to house particles of at least one catalyst element, and in that said main body comprises honeycomb type structure or in any case reticular with cells of any shape, that is to say, with the conduits arranged alongside each other.
A mixing channel for an inhalation device, comprising an inlet opening, an outlet opening, and an injection zone located between the inlet opening and the outlet opening, wherein the injection zone has a longitudinal center axis, wherein the injection zone comprises (a) a built-in nebulizer, or (b) a detachable nebulizer, or (c) a member adapted to receive a detachable nebulizer, and in that the effective cross sectional area of the mixing channel in a plane perpendicular to the longitudinal center axis decreases abruptly in the direction of air flow within or at the downstream end of the injection zone, such that said cross sectional area is smaller in the injection zone than upstream of the injection zone, characterized in that the abrupt decrease in cross sectional area is provided by a step in the mixing channel. (a) a built-in nebulizer, or (b) a detachable nebulizer, or (c) a member adapted to receive a detachable nebulizer,
An inhalation_apparatus comprising: a first cartridge comprising a first release device configured to release a first substance into a housing; a sensor (240, 291, 292, 293, 294, 295); and a controller (124, 224) configured to: receive data from the sensor (240, 291, 292, 293, 294, 295); determine an amount of first substance released by the first cartridge based on the data; and estimate a remaining amount of first substance in the first cartridge based on the determined amount of first substance. a first cartridge comprising a first release device configured to release a first substance into a housing; a sensor (240, 291, 292, 293, 294, 295); and a controller (124, 224) configured to: receive data from the sensor (240, 291, 292, 293, 294, 295); determine an amount of first substance released by the first cartridge based on the data; and estimate a remaining amount of first substance in the first cartridge based on the determined amount of first substance. receive data from the sensor (240, 291, 292, 293, 294, 295); determine an amount of first substance released by the first cartridge based on the data; and estimate a remaining amount of first substance in the first cartridge based on the determined amount of first substance.
A bolt has a head and a shaft for receiving a nut, at least a portion of which shaft is threaded, and at least one engagement means is provided on an underside of the head of the bolt and is located at an edge region of the head of the bolt; and the at least one engagement means is formed integrally with the head of the bolt, by at least one shaped portion which is cut and folded, and defines a scoop-shaped claw or tooth; characterized in that a notch is formed in a distal end of the shaft and the head of the bolt is square.
A computing system for configurable testing of a computer program, the computing system including: a storage medium and a configurable testing module; wherein the storage medium stores a set of one or more testing specifications (344, 346) and attribute information defining one or more attributes of a recognizable portion of the computer program, wherein the configurable testing module includes a processor that is configured to process the computer program according to a first testing specification associated with the computer program, wherein processing the computer program according to the first testing specification includes: traversing a representation of the computer program, while traversing the representation, recognizing recognizable portions of the computer program and storing values of attributes of the recognized portions of the computer program, and performing at least one test specified in at least the first testing specification based at least in part on stored values of attributes of one or more recognized portions of the computer program wherein the representation of the computer program includes elements that represent recognizable portions of the computer program, presenting the results of the test associated with the program representation and, wherein the attributes are defined by the attribute information. a storage medium and a configurable testing module; wherein the storage medium stores a set of one or more testing specifications (344, 346) and attribute information defining one or more attributes of a recognizable portion of the computer program, wherein the configurable testing module includes a processor that is configured to process the computer program according to a first testing specification associated with the computer program, wherein processing the computer program according to the first testing specification includes: traversing a representation of the computer program, while traversing the representation, recognizing recognizable portions of the computer program and storing values of attributes of the recognized portions of the computer program, and performing at least one test specified in at least the first testing specification based at least in part on stored values of attributes of one or more recognized portions of the computer program traversing a representation of the computer program, while traversing the representation, recognizing recognizable portions of the computer program and storing values of attributes of the recognized portions of the computer program, and performing at least one test specified in at least the first testing specification based at least in part on stored values of attributes of one or more recognized portions of the computer program wherein the representation of the computer program includes elements that represent recognizable portions of the computer program, presenting the results of the test associated with the program representation and, wherein the attributes are defined by the attribute information.
An input circuit arrangement, comprising - a terminal for supplying a terminal signal, and - an evaluation circuit which has its input side connected to the terminal and comprises a first and a second comparator (17, 18), which each have their input side connected to the terminal and are configured to compare the terminal signal or a signal derived from said terminal signal with a first and a second predefined threshold value (SREF1, SREF2), respectively, and to provide a first and a second comparator signal (SK1, SK2), respectively, depending on the result of the comparison, the evaluation circuit being configured to supply a clock signal exclusively depending on the first comparator signal and to supply a data signal exclusively depending on the second comparator signal, and the terminal signal comprising clock impulses which are based on a reference value and have a first height at a first logical value of the data signal, and an intermediate level, lying between the first height and the reference value, at a second logical value of the data signal, the input circuit arrangement comprising a signal converter, so that the input circuit arrangement is configured to have an influence on the terminal signal depending on an output signal (DOUT) or an inverted output signal (DOUTN) and thus deliver data to the terminal, wherein the signal converter comprises a resistive element and a switch, and a series connection comprising the switch and the resistive element connects the terminal to a reference potential terminal, and wherein the input circuit arrangement comprises a measurement object which is connected to the terminal via the resistive element and is coupled to the reference potential terminal via an activating switch. - a terminal for supplying a terminal signal, and - an evaluation circuit which has its input side connected to the terminal and comprises a first and a second comparator (17, 18), which each have their input side connected to the terminal and are configured to compare the terminal signal or a signal derived from said terminal signal with a first and a second predefined threshold value (SREF1, SREF2), respectively, and to provide a first and a second comparator signal (SK1, SK2), respectively, depending on the result of the comparison,