mhurhangee/ep-ind-claims huggingface dataset:
A producing method for a pluripotent stem cell capable of differentiating into a specific cell, the method comprising: (i) a step of measuring an expression level of a gene, which is expressed by a primitive endodermal cell, in a pluripotent stem cell as a sample; and (ii) a step of comparing the measured expression level of the gene, which is expressed by the primitive endodermal cell, with an expression level of the gene in a pluripotent stem cell known to have high differentiation potency into the specific cell, and selecting a pluripotent stem cell in which the measured expression level of the gene is less than one time relative to the expression level in the pluripotent stem cell known to have high differentiation potency into the specific cell, and acquiring a pluripotent stem cell capable of differentiating into the specific cell, wherein the gene expressed by the primitive endodermal cell is at least one gene selected from the group consisting of CER1, LEFTY1, LEFTY2, NODAL, and CXCR4, and wherein the specific cell is a differentiated cell derived from mesoderm or ectoderm. (i) a step of measuring an expression level of a gene, which is expressed by a primitive endodermal cell, in a pluripotent stem cell as a sample; and (ii) a step of comparing the measured expression level of the gene, which is expressed by the primitive endodermal cell, with an expression level of the gene in a pluripotent stem cell known to have high differentiation potency into the specific cell, and selecting a pluripotent stem cell in which the measured expression level of the gene is less than one time relative to the expression level in the pluripotent stem cell known to have high differentiation potency into the specific cell, and acquiring a pluripotent stem cell capable of differentiating into the specific cell, wherein the gene expressed by the primitive endodermal cell is at least one gene selected from the group consisting of CER1, LEFTY1, LEFTY2, NODAL, and CXCR4, and wherein the specific cell is a differentiated cell derived from mesoderm or ectoderm.
A medical device having: a central catheter with a lumen, said central catheter having the lumen as a central passage therethrough; a balloon disposed outside said central catheter, the balloon being inflatable and deflatable, with an inflated status during deployment, with an deflated status before deployment; a metallic mesh material disposed outside said balloon and surrounding said balloon, the medical device having a channel disposed between said metallic mesh material and said balloon, said channel being adapted to receive a channel guidewire, the medical device characterized in that the mesh material is premounted on the inflatable balloon, wherein the mesh material is to be expanded when the balloon is inflated during deployment, and in that openings through the metallic mesh material are provided in the channel at multiple locations along the channel so that the channel guidewire can pass into the channel and exit through one of the openings, wherein the channel has an additional wall located between the metallic mesh material and the balloon, and the channel has a first boundary by the balloon being folded and has a second boundary by the metallic mesh material. a central catheter with a lumen, said central catheter having the lumen as a central passage therethrough; a balloon disposed outside said central catheter, the balloon being inflatable and deflatable, with an inflated status during deployment, with an deflated status before deployment; a metallic mesh material disposed outside said balloon and surrounding said balloon, the medical device having a channel disposed between said metallic mesh material and said balloon, said channel being adapted to receive a channel guidewire, the medical device characterized in that the mesh material is premounted on the inflatable balloon, wherein the mesh material is to be expanded when the balloon is inflated during deployment, and in that openings through the metallic mesh material are provided in the channel at multiple locations along the channel so that the channel guidewire can pass into the channel and exit through one of the openings, wherein the channel has an additional wall located between the metallic mesh material and the balloon, and the channel has a first boundary by the balloon being folded and has a second boundary by the metallic mesh material. the channel has an additional wall located between the metallic mesh material and the balloon, and the channel has a first boundary by the balloon being folded and has a second boundary by the metallic mesh material.
A method of sibilance detection and mitigation, comprising: extracting a predetermined spectrum feature representing a distribution of signal energy over a voice frequency band from a voice signal; identifying sibilance based on the predetermined spectrum feature; identifying excessive sibilance based on a level of the identified sibilance; processing the voice signal by decreasing a level of the excessive sibilance so as to suppress the excessive sibilance; determining a ratio of the level of the identified sibilance to a long-term level of non-sibilance voices, wherein the identifying excessive sibilance based on a level of the identified sibilance comprises: determining whether the identified sibilance is excessive sibilance based on the ratio. extracting a predetermined spectrum feature representing a distribution of signal energy over a voice frequency band from a voice signal; identifying sibilance based on the predetermined spectrum feature; identifying excessive sibilance based on a level of the identified sibilance; processing the voice signal by decreasing a level of the excessive sibilance so as to suppress the excessive sibilance; determining a ratio of the level of the identified sibilance to a long-term level of non-sibilance voices, wherein the identifying excessive sibilance based on a level of the identified sibilance comprises: determining whether the identified sibilance is excessive sibilance based on the ratio.
A method for automatically generating an electronic dental chart for a patient, executed by a processor, comprising: obtaining (100; 104) image data for each of a plurality of teeth of the patient; generating a template dental chart for the patient representing the position of each of the plurality of teeth with a symbol according to and generated from the obtained image data, wherein the template dental chart is representative of one or more features of each of the plurality of teeth obtained from the image data; forming the electronic dental chart, by an automated procedure, by, for each of the plurality of teeth: (i) associating the obtained image data to the corresponding symbol in the template dental chart for the tooth; (ii) analyzing the obtained image data to identify a condition of the tooth; and (iii) associating the identified condition with the symbol for the tooth; and displaying the thus formed electronic dental chart, such that each symbol of the displayed electronic dental chart provides a visual indication of the identified condition. obtaining (100; 104) image data for each of a plurality of teeth of the patient; generating a template dental chart for the patient representing the position of each of the plurality of teeth with a symbol according to and generated from the obtained image data, wherein the template dental chart is representative of one or more features of each of the plurality of teeth obtained from the image data; forming the electronic dental chart, by an automated procedure, by, for each of the plurality of teeth: (i) associating the obtained image data to the corresponding symbol in the template dental chart for the tooth; (ii) analyzing the obtained image data to identify a condition of the tooth; and (iii) associating the identified condition with the symbol for the tooth; and (i) associating the obtained image data to the corresponding symbol in the template dental chart for the tooth; (ii) analyzing the obtained image data to identify a condition of the tooth; and (iii) associating the identified condition with the symbol for the tooth; and displaying the thus formed electronic dental chart, such that each symbol of the displayed electronic dental chart provides a visual indication of the identified condition.
A hybrid propulsion architecture for an aircraft, comprising: - a first source, of a first type, of electrical energy, - a plurality of second sources, of a second type, of electrical energy, said second type being different from said first type, - a plurality of electrical propulsion systems, - an electrical energy supply network connecting said first source and said second sources to said electrical propulsion systems such that each electrical propulsion system is powered by said first source and by one of said second sources, - propulsion channels, each propulsion channel comprising said first source, one of said second sources, one of said electrical propulsion systems, and a portion of the electrical energy supply network, said architecture being characterized in that it further comprises: - means for segregating said electrical propulsion systems, said segregation means being arranged on the electrical energy supply network and configured to impose a direction of flow of electric power from said first source to said electrical propulsion systems so that said propulsion channels are segregated. - a first source, of a first type, of electrical energy, - a plurality of second sources, of a second type, of electrical energy, said second type being different from said first type, - a plurality of electrical propulsion systems, - an electrical energy supply network connecting said first source and said second sources to said electrical propulsion systems such that each electrical propulsion system is powered by said first source and by one of said second sources, - propulsion channels, each propulsion channel comprising said first source, one of said second sources, one of said electrical propulsion systems, and a portion of the electrical energy supply network, - means for segregating said electrical propulsion systems, said segregation means being arranged on the electrical energy supply network and configured to impose a direction of flow of electric power from said first source to said electrical propulsion systems so that said propulsion channels are segregated.
A compound of formula IV: or a pharmaceutically acceptable salt thereof, wherein: X is N; and each R b is independently substituted or unsubstituted C 1-6 aliphatic; and n is 0 to 4. X is N; and each R b is independently substituted or unsubstituted C 1-6 aliphatic; and n is 0 to 4.
A bedrail mount for detachably attaching an object to a bedrail or bed board, the bedrail mount comprising first and second U shaped hook portions for receiving the bedrail or bed board, each U shaped hook portion comprising, a first leg (60, 22), a second leg (70, 21) and a connecting leg (80, 20) connecting the first and second legs, wherein the first leg of the first U shaped hook portion is attachable to the object and the second leg of the first U shaped hook portion includes the second U shaped hook portion, the first and second hook portions having an opening for receiving the bedrail or bed board, the opening of the second U shaped hook portion facing towards the first leg of the first U shaped hook portion, the first leg of the second U shaped portion being positioned at an end portion of the second leg of the first U shaped portion, characterized in that the first leg of the first U shaped hook portion comprises at its end portion a protrusion pointing towards the second leg of the first U shaped hook portion, the opening of the first U shaped hook portion being the smallest distance between the end portion of the protrusion and the second leg of the first U shaped portion, and in that the opening of the first U shaped hook portion is larger than the length of the connecting leg connecting the first and second legs (60, 70) of the first U shaped portion.
Method for setting a pressure medium supply for at least one hydraulic actuator, wherein - the actuator is supplied with a pressure medium by a displacement unit whose displacement volume can be adjusted, - the displacement unit is driven by a variable-speed drive and - a pressure medium quantity to be supplied to the actuator is specified by a variable profile characterized in that a speed setpoint value of the drive and/or a setpoint value for the displacement volume of the displacement unit is set taking into account a knowledge-based decision system, wherein the variable profile is supplied to the knowledge-based decision system as an input variable. - the actuator is supplied with a pressure medium by a displacement unit whose displacement volume can be adjusted, - the displacement unit is driven by a variable-speed drive and - a pressure medium quantity to be supplied to the actuator is specified by a variable profile
An image stabilization apparatus comprising: a fixed member; a movable member configured to hold an image stabilization lens and movable relative to the fixed member on a plane perpendicular to an optical axis (α) of the image stabilization lens; and a lock member that is disposed on an outer circumference side of the movable member and can be positioned at a lock position for restricting a movement of the movable member and an unlock position for enabling the movement of the movable member; characterized by a retaining member configured to fix the movable member in an eccentric state when the lock member is located at the lock position. a fixed member; a movable member configured to hold an image stabilization lens and movable relative to the fixed member on a plane perpendicular to an optical axis (α) of the image stabilization lens; and a lock member that is disposed on an outer circumference side of the movable member and can be positioned at a lock position for restricting a movement of the movable member and an unlock position for enabling the movement of the movable member; characterized by a retaining member configured to fix the movable member in an eccentric state when the lock member is located at the lock position.
A sterile therapeutic composition for use in a method for treating a subject having villous atrophy caused by radiation or chemotherapy, wherein the composition is formulated for enteral administration and comprises one or more free amino acids selected from lysine, glycine, threonine, valine, tyrosine, aspartic acid, isoleucine, tryptophan and serine; and water; wherein the composition has a total osmolarity from 230 mosm to 280 mosm; and wherein the composition does not comprise one or more ingredients selected from glucose, glutamine and methionine; or, if these ingredients are present, glucose is present at a concentration of less than 1g/l, glutamine is present at a concentration of less than 300 mg/l, and methionine is present at a concentration of less than 300 mg/l.
A microporous material comprising: (a) a matrix of water-insoluble thermoplastic organic polymer comprising polyolefin; (b) finely divided, water-insoluble particulate filler, said particulate filler being distributed throughout said matrix and constituting from 20 to 90 percent by weight, based on the total weight of said microporous material; and (c) a network of interconnecting pores communicating throughout said microporous material; wherein said microporous material has, - a volatile material contact surface, - a vapor release surface, wherein said volatile material contact surface and said vapor release surface are opposed to each other, and wherein (i) at least a portion of said volatile material contact surface has a first coating thereon, and/or (ii) at least a portion of said vapor release surface has a second coating thereon, and the first and second coating each independently can be formed from an aqueous coating composition that includes dispersed organic polymeric material. (a) a matrix of water-insoluble thermoplastic organic polymer comprising polyolefin; (b) finely divided, water-insoluble particulate filler, said particulate filler being distributed throughout said matrix and constituting from 20 to 90 percent by weight, based on the total weight of said microporous material; and (c) a network of interconnecting pores communicating throughout said microporous material; - a volatile material contact surface, - a vapor release surface, wherein said volatile material contact surface and said vapor release surface are opposed to each other, and wherein (i) at least a portion of said volatile material contact surface has a first coating thereon, and/or (ii) at least a portion of said vapor release surface has a second coating thereon, and the first and second coating each independently can be formed from an aqueous coating composition that includes dispersed organic polymeric material.
A cartridge nest for holding a plurality of cartridges (700, 1300) comprising: a syringe nest (894, 994a, 994b, 1094, 1194, 1594, 1694) defining a horizontal array of cartridge mounts each said mount for supporting a cartridge (700, 1300), each said mount including an aperture (996, 1096) or channel sized and shaped to allow a distal portion (109, 709) of a cartridge (700, 1300) of said plurality of cartridges (700, 1300) to pass through said syringe nest (894, 994a, 994b, 1094, 1194, 1594, 1694), a support surface shaped to prevent the proximal portion (102, 702) of said cartridge (700, 1300) from passing through the aperture (996, 1096), such that the cartridge (700, 1300) hangs supported on said support surface and said distal portion (109, 709) protruding downward through said aperture (996, 1096), and an orientation feature (399, 499, 844, 899, 1199) on the cartridge nest sized and shaped to rotationally interlock with said cartridge (700, 1300) to fix an angular orientation of said cartridge (700, 1300) around its longitudinal axis when the cartridge (700, 1300) is hanging from said support surface, said orientation feature (399, 499, 844, 899, 1199) making said mount not continually rotationally symmetric, characterised in that said orientation feature (399, 499, 844, 899, 1199) is non-symmetric with respect to 180 degree rotation around said axis of said cartridge (700, 1300). an aperture (996, 1096) or channel sized and shaped to allow a distal portion (109, 709) of a cartridge (700, 1300) of said plurality of cartridges (700, 1300) to pass through said syringe nest (894, 994a, 994b, 1094, 1194, 1594, 1694), a support surface shaped to prevent the proximal portion (102, 702) of said cartridge (700, 1300) from passing through the aperture (996, 1096), such that the cartridge (700, 1300) hangs supported on said support surface and said distal portion (109, 709) protruding downward through said aperture (996, 1096), and an orientation feature (399, 499, 844, 899, 1199) on the cartridge nest sized and shaped to rotationally interlock with said cartridge (700, 1300) to fix an angular orientation of said cartridge (700, 1300) around its longitudinal axis when the cartridge (700, 1300) is hanging from said support surface, said orientation feature (399, 499, 844, 899, 1199) making said mount not continually rotationally symmetric, characterised in that said orientation feature (399, 499, 844, 899, 1199) is non-symmetric with respect to 180 degree rotation around said axis of said cartridge (700, 1300).
A bioadhesive formulation comprising: a) gelatin; b) alginate; c) a coupling agent that promotes crosslinking between gelatin and alginate; and d) water, wherein a concentration of said gelatin in the formulation ranges from 200 mg/ml to 300 mg/ml, a concentration of said alginate ranges from 20 mg/ml to 40 mg/ml and a concentration of said coupling agent ranges from 10 mg/ml to 30 mg/ml, the formulation being characterized by a room temperature viscosity that ranges from 1 Pa-sec to 50 Pa-sec. a) gelatin; b) alginate; c) a coupling agent that promotes crosslinking between gelatin and alginate; and d) water,
A slide rail assembly, comprising: a first rail comprising a blocking feature; a second rail (20, 200) movably connected to the first rail and longitudinally displaceable relative to the first rail from a retracted position to a first extended position and a second extended position; an engaging member attached to the second rail (20, 200); and characterized in that an operation member (48, 202) mounted to at least one of the first rail and the second rail (20, 200) and configured to be used to operate the engaging member, wherein when the second rail (20, 200) is displaced relative to the first rail to the first extended position, the operation member (48, 202) is able to be operated so that at least a portion of the engaging member is blocked by the blocking feature of the first rail and thus retains the second rail (20, 200) at the first extended position relative to the first rail, and wherein the operational member (48, 202) is able to be operated to release the engaging member from the blocking feature of the first rail so that the second rail can be further displaced relative to the first rail in the extension direction until the second extended position is reached. a first rail comprising a blocking feature; a second rail (20, 200) movably connected to the first rail and longitudinally displaceable relative to the first rail from a retracted position to a first extended position and a second extended position; an engaging member attached to the second rail (20, 200); and characterized in that an operation member (48, 202) mounted to at least one of the first rail and the second rail (20, 200) and configured to be used to operate the engaging member, wherein when the second rail (20, 200) is displaced relative to the first rail to the first extended position, the operation member (48, 202) is able to be operated so that at least a portion of the engaging member is blocked by the blocking feature of the first rail and thus retains the second rail (20, 200) at the first extended position relative to the first rail, and wherein the operational member (48, 202) is able to be operated to release the engaging member from the blocking feature of the first rail so that the second rail can be further displaced relative to the first rail in the extension direction until the second extended position is reached.