A process for preparing a compound of Formula: wherein R 1 is selected from the group consisting of: 1) substituted or unsubstituted -C 1 -C 8 alkyl; 2) substituted or unsubstituted -C 2 -C 8 alkenyl; 3) substituted or unsubstituted -C 2 -C 8 alkynyl; 4) substituted or unsubstituted -C 3 -C 8 cycloalkyl; 5) substituted or unsubstituted aryl; 6) substituted or unsubstituted arylalkyl; 7) substituted or unsubstituted 3- to 12- membered heterocycloalkyl; 8) substituted or unsubstituted heteroaryl; 9) substituted or unsubstituted heteroarylalkyl; and 10) NR a R b, wherein, R a and R b are each independently selected from hydrogen, substituted or unsubstituted -C 1 -C 8 alkyl, substituted or unsubstituted -C 2 -C 8 alkenyl, substituted or unsubstituted -C 2 -C 8 alkynyl, substituted or unsubstituted -C 3 -C 8 cycloalkyl; alternatively R a and R b are taken together with the nitrogen atom to which they attached to form a 3- to 12- memebered hetercyclic ring; said process comprising the steps of: converting compound 1, to compound wherein PG is a hydroxyl protecting group, wherein said conversion comprises the steps of reacting compound 1 with a C 1 -C 6 -alkanol under acid catalysis to produce compound 2, wherein R 6 is C 1 -C 6 -alkyl; reacting compound 2 with a strong base in the presence of a hydroxyl protecting agent to produce a compound of Formula 2a, and reacting the compound of Formula 2a with a halogenating agent to produce compound 3, wherein PG 1 is a hydroxyl protecting group; and R 2 is selected from Br, I, and Cl; (1aiii) reacting compound 3 with an organic base to eliminate HR 2 and produce compound 4, deprotecting compound 4 to produce compound 5, reacting compound 5 with a hydroxyl protecting agent to produce compound 6:; and oxidatively cleaving and oxidizing compound 6 in the presence of a base to produce the compound of Formula: converting compound to compound and converting compound to the compound of Formula. 1) substituted or unsubstituted -C 1 -C 8 alkyl; 2) substituted or unsubstituted -C 2 -C 8 alkenyl; 3) substituted or unsubstituted -C 2 -C 8 alkynyl; 4) substituted or unsubstituted -C 3 -C 8 cycloalkyl; 5) substituted or unsubstituted aryl; 6) substituted or unsubstituted arylalkyl; 7) substituted or unsubstituted 3- to 12- membered heterocycloalkyl; 8) substituted or unsubstituted heteroaryl; 9) substituted or unsubstituted heteroarylalkyl; and 10) NR a R b, wherein, R a and R b are each independently selected from hydrogen, substituted or unsubstituted -C 1 -C 8 alkyl, substituted or unsubstituted -C 2 -C 8 alkenyl, substituted or unsubstituted -C 2 -C 8 alkynyl, substituted or unsubstituted -C 3 -C 8 cycloalkyl; alternatively R a and R b are taken together with the nitrogen atom to which they attached to form a 3- to 12- memebered hetercyclic ring; converting compound 1, to compound wherein PG is a hydroxyl protecting group, wherein said conversion comprises the steps of reacting compound 1 with a C 1 -C 6 -alkanol under acid catalysis to produce compound 2, wherein R 6 is C 1 -C 6 -alkyl; reacting compound 2 with a strong base in the presence of a hydroxyl protecting agent to produce a compound of Formula 2a, and reacting the compound of Formula 2a with a halogenating agent to produce compound 3, wherein PG 1 is a hydroxyl protecting group; and R 2 is selected from Br, I, and Cl; (1aiii) reacting compound 3 with an organic base to eliminate HR 2 and produce compound 4, deprotecting compound 4 to produce compound 5, reacting compound 5 with a hydroxyl protecting agent to produce compound 6:; and oxidatively cleaving and oxidizing compound 6 in the presence of a base to produce the compound of Formula: reacting compound 1 with a C 1 -C 6 -alkanol under acid catalysis to produce compound 2, wherein R 6 is C 1 -C 6 -alkyl; reacting compound 2 with a strong base in the presence of a hydroxyl protecting agent to produce a compound of Formula 2a, and reacting the compound of Formula 2a with a halogenating agent to produce compound 3, wherein PG 1 is a hydroxyl protecting group; and R 2 is selected from Br, I, and Cl; PG 1 is a hydroxyl protecting group; and R 2 is selected from Br, I, and Cl; (1aiii) reacting compound 3 with an organic base to eliminate HR 2 and produce compound 4, deprotecting compound 4 to produce compound 5, reacting compound 5 with a hydroxyl protecting agent to produce compound 6:; and oxidatively cleaving and oxidizing compound 6 in the presence of a base to produce the compound of Formula: converting compound to compound and converting compound to the compound of Formula.