mhurhangee/ep-ind-claims huggingface dataset:
An isolated or purified single domain antibody or antigen-binding fragment thereof, comprising a complementarity determining region 1 sequence of EYPSNFYA (SEQ ID NO:1); a CDR2 sequence of VSRDGLTT (SEQ ID NO:2); and a CDR3 sequence of AIVITGVWNKVDVNSRSYHY (SEQ ID NO:3), wherein the antibody or antigen-binding fragment thereof is specific for Insulin-Like Growth Factor 1 Receptor (IGF1R).
An energy storage module comprising: one or more cells; a body having a first wall and a second wall arranged transversely to the first wall (3, 4), the first wall and the second wall running parallel to an axis; and a cavity in the body containing said one or more cells, the cavity being at least partially defined by the first wall and the second wall; wherein the first wall includes first and second heat conducting layers to form a first heat dissipating path in a first direction which extends transverse to the axis; and the second wall includes first and second heat insulating layers to form a heat conduction barrier for preventing heat dissipation in a second direction that extends transverse to the first direction and the axis; wherein the body is configured to promote heat dissipation in a third direction which extends parallel to the axis; and characterised in that the body includes a heat conducting connector for connecting said one or more cells to the first heat conducting layer thereby forming a second heat dissipation path that at least partially extends in the third direction.. one or more cells; a body having a first wall and a second wall arranged transversely to the first wall (3, 4), the first wall and the second wall running parallel to an axis; and a cavity in the body containing said one or more cells, the cavity being at least partially defined by the first wall and the second wall; wherein the first wall includes first and second heat conducting layers to form a first heat dissipating path in a first direction which extends transverse to the axis; and the second wall includes first and second heat insulating layers to form a heat conduction barrier for preventing heat dissipation in a second direction that extends transverse to the first direction and the axis; wherein the body is configured to promote heat dissipation in a third direction which extends parallel to the axis; and characterised in that the body includes a heat conducting connector for connecting said one or more cells to the first heat conducting layer thereby forming a second heat dissipation path that at least partially extends in the third direction..
Spring plate for a tappet assembly of a high-pressure pump in a fuel injection system, wherein the spring plate is in particular a bent and punched part, and wherein the spring plate has a central recess for receiving a pump piston, wherein the spring plate furthermore has at least two arcuately running recesses which are arranged around the central recess and which serve for forming a radially inner support ring and a radially outer support ring which are connected to one another by means of substantially radially running webs, characterized in that the radially inner support ring has regions (9, 10) which are elevated and sunken relative to a plane and which are arranged in each case with an angular spacing to the substantially radially running webs and which give rise to a circular undulation of the inner support ring and to elastic deformability of the spring plate.
A thermoplastic polymer composition comprising (i) a vinyl halide polymer, and (ii) from 0.1 to 12 phr (parts solids per hundred weight parts solids of vinyl halide polymer) of a multi-stage acrylic copolymer having a first stage polymer and a second stage polymer, the first stage polymer of from 25 to 78.5 wt.%, of, in copolymerized form, (a) at least one C 1 to C 6 alkyl methacrylate or C 1 to C 4 alkyl acrylate, from 0 to 75 wt.% of (b) one or more other polar vinyl monomers, and no more than 10 wt.% of (c) vinyl aromatic monomers, all monomer proportions, based on the total weight of monomers used to make the first stage polymer, the first stage polymer having a weight average molecular weight as measured by gel permeation chromatography against polystyrene standards of from 1 x 10 6 to 10 x 10 6 g/mol and having a glass transition temperature as calculated by the Fox Equation (calculated Tg) of from 70 to 105 °C; and a second stage polymer of, in copolymerized form, (d) at least one C 4 to C 18 alkyl acrylate or C 8 to C 18 alkyl methacrylate, from 0 to 75 wt.% total of (c) one or more vinyl aromatic monomers, and the remainder of (b) one or more polar vinyl monomers, all monomer proportions based on the total weight of monomers used to make the second stage polymer, the second stage polymer having a weight average molecular weight (Mw) as measured by GPC against polystyrene standards of from 1,000 to 100,000 g/mol, and having a calculated Tg of from -65 to 45°C, the solids weight ratio of the first stage polymer to the second stage polymer ranging from 1:3 to 7:1, wherein the multistage acrylic copolymer is substantially free of added acid group functional monomers and such monomers in copolymerized form.
A catheter, comprising: an elongated member having a proximal end, a distal end, and a body extending between the proximal end and the distal end; wherein the elongated member comprises a tubular section having a plurality of openings, in the form of slots extending into a wall of the tubular section, the plurality of slots comprising a first slot; and wherein the elongated member further comprises fillers respectively located in the slots, the fillers comprising a first filler, wherein the first filler comprises a spongy material located in the first slot; wherein the first filler has an elastic modulus that is less than 10% of an elastic modulus of a material of the tubular section, and wherein the first filler is compressible to reach a strain that is at least 0.1; wherein the first slot is at the wall of the tubular section, the first slot extending circumferentially around a longitudinal axis of the tubular section, and that the first filler having the elastic modulus is located in the first slot extending circumferentially around the longitudinal axis of the tubular section characterized in that the spongy material in the first slot comprises a porous material. an elongated member having a proximal end, a distal end, and a body extending between the proximal end and the distal end; wherein the elongated member comprises a tubular section having a plurality of openings, in the form of slots extending into a wall of the tubular section, the plurality of slots comprising a first slot; and wherein the elongated member further comprises fillers respectively located in the slots, the fillers comprising a first filler, wherein the first filler comprises a spongy material located in the first slot; wherein the first filler has an elastic modulus that is less than 10% of an elastic modulus of a material of the tubular section, and wherein the first filler is compressible to reach a strain that is at least 0.1; wherein the first slot is at the wall of the tubular section, the first slot extending circumferentially around a longitudinal axis of the tubular section, and that the first filler having the elastic modulus is located in the first slot extending circumferentially around the longitudinal axis of the tubular section characterized in that the spongy material in the first slot comprises a porous material.
A connector, comprising: - a first junction including a) a shell conductor forming a containing space therein and grounded; b) a control circuit triggered when grounded; and c) a controlling conductor disposed on one side of the containing space, electrically insulated from the shell conductor, and electrically connected to the control circuit; and - a second junction including a) an insulator movably disposed in the containing space; b) a signal conductor disposed within the insulator; and c) a flexible conductor disposed on the insulator and having a propping end contacting the shell conductor and a connecting end separated from the controlling conductor by a distance (d), wherein the insulator is movable to push the connecting end toward the controlling conductor by the distance (d), such that the connecting end contacts the controlling conductor so that the control circuit is grounded through the controlling conductor, the flexible conductor and the shell conductor. - a first junction including a) a shell conductor forming a containing space therein and grounded; b) a control circuit triggered when grounded; and c) a controlling conductor disposed on one side of the containing space, electrically insulated from the shell conductor, and electrically connected to the control circuit; and a) a shell conductor forming a containing space therein and grounded; b) a control circuit triggered when grounded; and c) a controlling conductor disposed on one side of the containing space, electrically insulated from the shell conductor, and electrically connected to the control circuit; and - a second junction including a) an insulator movably disposed in the containing space; b) a signal conductor disposed within the insulator; and c) a flexible conductor disposed on the insulator and having a propping end contacting the shell conductor and a connecting end separated from the controlling conductor by a distance (d), wherein the insulator is movable to push the connecting end toward the controlling conductor by the distance (d), such that the connecting end contacts the controlling conductor so that the control circuit is grounded through the controlling conductor, the flexible conductor and the shell conductor. a) an insulator movably disposed in the containing space; b) a signal conductor disposed within the insulator; and c) a flexible conductor disposed on the insulator and having a propping end contacting the shell conductor and a connecting end separated from the controlling conductor by a distance (d),
A linear peristaltic pump for pumping a fluid through a flexible tube, comprising: - a central member mounted for rotation about a central shaft; - a plurality of planetary gears (51- 53) mounted by a plurality of planetary gear shafts (51 S-53S) to said central member, respectively; - a ring gear disposed in a mesh engagement with each of said plurality of planetary gears; characterized in that the pump comprises: - a roller disposed on each of said planetary gears (51- 53) offset from said planetary gear shafts (51S - 53S), respectively; and - a generally flat compression surface located relative to said central shaft for enabling the flexible tube to be inserted between said generally flat compression surface and at least one of said plurality of rollers; and - a motor for effecting relative rotation between said central member and said ring gear for enabling said plurality of rollers to serially collapse the flexible tube and to move in a substantially linear motion along said generally flat compression surface for pumping the fluid through the flexible tube, - a central member mounted for rotation about a central shaft; - a plurality of planetary gears (51- 53) mounted by a plurality of planetary gear shafts (51 S-53S) to said central member, respectively; - a ring gear disposed in a mesh engagement with each of said plurality of planetary gears; characterized in that the pump comprises: - a roller disposed on each of said planetary gears (51- 53) offset from said planetary gear shafts (51S - 53S), respectively; and - a generally flat compression surface located relative to said central shaft for enabling the flexible tube to be inserted between said generally flat compression surface and at least one of said plurality of rollers; and - a motor for effecting relative rotation between said central member and said ring gear for enabling said plurality of rollers to serially collapse the flexible tube and to move in a substantially linear motion along said generally flat compression surface for pumping the fluid through the flexible tube,
Assembly for adding at least one functionality to an electrical load, the assembly comprising: - a control module adapted for adding a functionality to the electrical load, the control module comprising a first switch provided between the electrical load and a branch point, the branch point being intended for connecting with a set of power supply lines (41, 43) for providing power supply to the control module and the electrical load; - a power supply restoration module configured to restore the power supply of the control module in the event of a power supply interruption as a result of a switching operation of a user-operated switch (50, 51, 52) in the set of power supply lines (41, 43) towards the electrical load; and - a control circuit configured to detect a power supply interruption in the set of power supply lines (41, 43), characterized in that the power supply restoration module comprises a second switch provided in the set of power supply lines (41, 43) and that the control circuit is adapted to, upon detecting a power supply interruption as a result of the switching operation of the user-operated switch, switch the first switch off; and to, after switching the first switch off, switch the second switch. - a control module adapted for adding a functionality to the electrical load, the control module comprising a first switch provided between the electrical load and a branch point, the branch point being intended for connecting with a set of power supply lines (41, 43) for providing power supply to the control module and the electrical load; - a power supply restoration module configured to restore - a control circuit configured to detect a power supply interruption in the set of power supply lines (41, 43),
A method for constructing an offshore structure, wherein the method comprises: a manufacturing step of manufacturing an offshore structure separated in an upper structure and a lower structure; an in-water keeping step of keeping part or whole of the lower structure in an upright standing state in water; a moving step of moving the upper structure to above the lower structure kept in the upright standing state; an uniting step of performing a raising step of raising the lower structure to arrange the lower structure on a lower side of the upper structure which is placed on a carrier vessel that carries the upper structure; and a joining step of integrating the lower structure with the upper structure. a manufacturing step of manufacturing an offshore structure separated in an upper structure and a lower structure; an in-water keeping step of keeping part or whole of the lower structure in an upright standing state in water; a moving step of moving the upper structure to above the lower structure kept in the upright standing state; an uniting step of performing a raising step of raising the lower structure to arrange the lower structure on a lower side of the upper structure which is placed on a carrier vessel that carries the upper structure; and a joining step of integrating the lower structure with the upper structure.
A method for measuring optical properties of an optically variable marking applied on an object, said method comprising: illuminating said optically variable marking so as to form a first light (l 1) reflected by the marking at a first view angle and a second light (l 2) reflected by the marking at a second view angle, the first and second lights having different spectral compositions as a result of the optically variable marking; refracting said second reflected light (l 2) through an optical unit so as to redirect said second reflected light toward an optical sensor; simultaneously capturing the first reflected light and the second refracted light with said optical sensor during the same integration time; and determining optical properties of said optical variable marking based on said captured first reflected light and second refracted light, said determining being carried out by a processing unit, characterized by said determining comprising: comparing the spectral profiles for both the first and second light as a function of the wavelength, with reference profiles that are stored in the processing unit. illuminating said optically variable marking so as to form a first light (l 1) reflected by the marking at a first view angle and a second light (l 2) reflected by the marking at a second view angle, the first and second lights having different spectral compositions as a result of the optically variable marking; refracting said second reflected light (l 2) through an optical unit so as to redirect said second reflected light toward an optical sensor; simultaneously capturing the first reflected light and the second refracted light with said optical sensor during the same integration time; and determining optical properties of said optical variable marking based on said captured first reflected light and second refracted light, said determining being carried out by a processing unit, characterized by said determining comprising: comparing the spectral profiles for both the first and second light as a function of the wavelength, with reference profiles that are stored in the processing unit.
A dressing for use with negative-pressure treatment on a foot, the dressing comprising: a tissue interface comprising: a hindfoot section comprising at least two heel flaps, a midfoot section, a forefoot section, a forefoot extension configured to fold over the forefoot section, a fluid control layer having a plurality of fluid restrictions, and a manifold adhered to the fluid control layer in a stacked relationship across the hindfoot section, the midfoot section, the forefoot section, and the forefoot extension; and a cover comprising a non-porous film having an open end configured to receive the tissue interface applied to the foot. a tissue interface comprising: a hindfoot section comprising at least two heel flaps, a midfoot section, a forefoot section, a forefoot extension configured to fold over the forefoot section, a fluid control layer having a plurality of fluid restrictions, and a manifold adhered to the fluid control layer in a stacked relationship across the hindfoot section, the midfoot section, the forefoot section, and the forefoot extension; and a hindfoot section comprising at least two heel flaps, a midfoot section, a forefoot section, a forefoot extension configured to fold over the forefoot section, a fluid control layer having a plurality of fluid restrictions, and a manifold adhered to the fluid control layer in a stacked relationship across the hindfoot section, the midfoot section, the forefoot section, and the forefoot extension; and a cover comprising a non-porous film having an open end configured to receive the tissue interface applied to the foot.
A modified MBNL polypeptide having an YGCY binding property, and having a splicing activity reduced by at least 60% as compared to wild-type MBNL protein, for use as a medicament, wherein said polypeptide is not a chimeric peptide consisting of MBNL polypeptide and a targeting moiety.
A method of operating a wireless communication device, comprising: - monitoring for signals from a communications network (100, 101, 109) in a connected mode of the wireless communication device with a receive beam configuration, and - storing the receive beam configuration, - monitoring for further signals from the communications network (100, 101, 109) in a disconnected mode (302, 303) of the wireless communication device with the stored receive beam configuration until occurrence of at least one predefined event (261, 261-1, 261-2), - monitoring for the further signals in the disconnected mode (302, 303) with a further receive beam configuration after the occurrence of the at least one predefined event (261, 261-1, 261-2), the further receive beam configuration being different from the stored receive beam configuration, wherein the further signals comprise paging signals, and - using a first paging configuration for monitoring for the paging signals while monitoring for the paging signals using the stored receive beam configuration until the occurrence of the at least one predefined event (261, 261-1, 261-2), and - using a second paging configuration for monitoring for the paging signals while monitoring for the paging signals using the further receive beam configuration after the occurrence of the at least one predefined event (261, 261 - 1, 261-2), the first paging configuration being different from the second paging configuration. - monitoring for signals from a communications network (100, 101, 109) in a connected mode of the wireless communication device with a receive beam configuration, and - storing the receive beam configuration, - monitoring for further signals from the communications network (100, 101, 109) in a disconnected mode (302, 303) of the wireless communication device with the stored receive beam configuration until occurrence of at least one predefined event (261, 261-1, 261-2), - monitoring for the further signals in the disconnected mode (302, 303) with a further receive beam configuration after the occurrence of the at least one predefined event (261, 261-1, 261-2), the further receive beam configuration being different from the stored receive beam configuration, wherein the further signals comprise paging signals, and - using a first paging configuration for monitoring for the paging signals while monitoring for the paging signals using the stored receive beam configuration until the occurrence of the at least one predefined event (261, 261-1, 261-2), and - using a second paging configuration for monitoring for the paging signals while monitoring for the paging signals using the further receive beam configuration after the occurrence of the at least one predefined event (261, 261 - 1, 261-2), the first paging configuration being different from the second paging configuration.