Compound bearing at least two fucose moieties for its use as a drug in the prevention or treatment of infections caused by Aspergillus spp, said compound having a molecular weight comprised from 0.6 to 340 kDa, in particular from 0.6 to 2 kDa or from 1 to 7 kDa or from 2 to 10 kDa or from 5 to 340 kDa; in particular, said compound being of formula A - i - B - C wherein ▪ i is equal to 0 or 1; ▪ A is selected from k being equal to 1, 2, or 3; k being in particular equal to 1; r being comprised from 1 to 30, in particular from 1 to 4, from 5 to 9, from 10 to 15, from 16 to 20, from 21 to 25 or from 26 to 30; s being comprised from 5 to 300; in particular from 60 to 80; v being comprised from 0 to 10; in particular from 1 to 8; preferably v being equal to 3; ▪ B is of formula ▪ C is of formula y being equal to 0 or 1; X being selected from O, S or CH 2; U being selected from m being comprised from 0 to 8, n being comprised from 0 to 8, p being comprised from 1 to 10, q being comprised from 1 to 10, or R 1, R 2, R 3 and R 4 being independently from each other selected from H, COCH 3, NH 2, NO 2, NHAc, OH, OMe, COOH, COOMe, CONHMe, Cl, Br, I, F, SMe or Me; provided that y+n or y+m is different from 0; in particular, m being comprised from 1 to 5; in particular, n being comprised from 0 to 5; ▪ D being selected from j being comprised from 0 to 8. ▪ i is equal to 0 or 1; ▪ A is selected from k being equal to 1, 2, or 3; k being in particular equal to 1; r being comprised from 1 to 30, in particular from 1 to 4, from 5 to 9, from 10 to 15, from 16 to 20, from 21 to 25 or from 26 to 30; s being comprised from 5 to 300; in particular from 60 to 80; v being comprised from 0 to 10; in particular from 1 to 8; preferably v being equal to 3; k being equal to 1, 2, or 3; k being in particular equal to 1; r being comprised from 1 to 30, in particular from 1 to 4, from 5 to 9, from 10 to 15, from 16 to 20, from 21 to 25 or from 26 to 30; s being comprised from 5 to 300; in particular from 60 to 80; v being comprised from 0 to 10; in particular from 1 to 8; preferably v being equal to 3; ▪ B is of formula ▪ C is of formula y being equal to 0 or 1; X being selected from O, S or CH 2; U being selected from m being comprised from 0 to 8, n being comprised from 0 to 8, p being comprised from 1 to 10, q being comprised from 1 to 10, or R 1, R 2, R 3 and R 4 being independently from each other selected from H, COCH 3, NH 2, NO 2, NHAc, OH, OMe, COOH, COOMe, CONHMe, Cl, Br, I, F, SMe or Me; provided that y+n or y+m is different from 0; in particular, m being comprised from 1 to 5; in particular, n being comprised from 0 to 5; y being equal to 0 or 1; X being selected from O, S or CH 2; U being selected from m being comprised from 0 to 8, n being comprised from 0 to 8, p being comprised from 1 to 10, q being comprised from 1 to 10, or R 1, R 2, R 3 and R 4 being independently from each other selected from H, COCH 3, NH 2, NO 2, NHAc, OH, OMe, COOH, COOMe, CONHMe, Cl, Br, I, F, SMe or Me; provided that y+n or y+m is different from 0; in particular, m being comprised from 1 to 5; in particular, n being comprised from 0 to 5; ▪ D being selected from j being comprised from 0 to 8.