Compound selected from the group consisting of pantothenamide analogues represented by formula and pharmaceutically acceptable salts and esters thereof: wherein n = 1, 2, 3 or 4 m = 0, 1, 2, 3 or 4 moiety R a and R a' are independently selected from the group consisting of (C 1 -C 6)alkyl, (C 1 -C 6)alkenyl, (C 1 -C 6)alkynyl, branched (C 3 -C 6)alkyl, O(C 1 -C 5)alkyl and CH 2 -O-C 1 -C 4 alkyl; or R a and R a' are joined together to form a single moiety selected from the group consisting of-(C 3 -C 6)alkyl-, -(C 1 -C 2)alkyl-O-(C 1 -C 2)alkyl- and -(C 1 -C 2)alkyl-NR-(C 1 -C 2)alkyl-, wherein R represents hydrogen or C 1 -C 6 alkyl; R b and R b' are independently selected from the group consisting of hydrogen, (C 1 -C 6)alkyl, (C 1 -C 6)alkenyl, (C 1 -C 6)alkynyl, branched (C 3 -C 6)alkyl, (C 3 -C 6)cycloalkyl and aryl; and R 1 represents: - an aliphatic or heteroaliphatic moiety selected from the group consisting of C 1 -C 10 alkyl, C 2 -C 10 -alkenyl, C 2 -C 10 -alkynyl, C 1 -C 5 -alkyl-C 3 -C 6 cycloalkyl, (C 1 -C y)-O-(C 1 -C x) and (C 1 -C y)-S-(C 1 -C x), wherein y and x each represent an integer in the range of 0-7 and wherein y+x≤7, each moiety optionally being substituted with 1-3 substituents independently selected from halo, C 1 -C 6 alkyl, C 3 -C 6 cylcoalkyl, phenyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy and CH 2 -O-C 1 -C 6 alkyl - an aromatic moiety selected from the group consisting of phenyl and naphtyl, each optionally substituted with 1-3 substituents independently selected from halo, C 1 -C 6 alkyl, C 3 -C 6 cylcoalkyl, phenyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy and CH 2 -O-C 1 -C 6 alkyl; or - a heteroaromatic moiety selected from the group consisting of thienyl, benzothienyl, furyl, benzopyranyl, pyrol, indolyl, pyran, pyrimidine, triazine, pyridyl, quinolyl, isoquinolyl, isoxazole, oxazole, pyrazole, thiazole, imidazole, triazole, oxadiazole, thiadiazole and tetrazole, each optionally substituted with 1-3 substituents independently selected from halo, C 1 -C 6 alkyl, C 3 -C 6 cylcoalkyl, phenyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy and CH 2 -O-C 1 -C 6 alkyl. n = 1, 2, 3 or 4 m = 0, 1, 2, 3 or 4 moiety R a and R a' are independently selected from the group consisting of (C 1 -C 6)alkyl, (C 1 -C 6)alkenyl, (C 1 -C 6)alkynyl, branched (C 3 -C 6)alkyl, O(C 1 -C 5)alkyl and CH 2 -O-C 1 -C 4 alkyl; or R a and R a' are joined together to form a single moiety selected from the group consisting of-(C 3 -C 6)alkyl-, -(C 1 -C 2)alkyl-O-(C 1 -C 2)alkyl- and -(C 1 -C 2)alkyl-NR-(C 1 -C 2)alkyl-, wherein R represents hydrogen or C 1 -C 6 alkyl; R b and R b' are independently selected from the group consisting of hydrogen, (C 1 -C 6)alkyl, (C 1 -C 6)alkenyl, (C 1 -C 6)alkynyl, branched (C 3 -C 6)alkyl, (C 3 -C 6)cycloalkyl and aryl; and R 1 represents: - an aliphatic or heteroaliphatic moiety selected from the group consisting of C 1 -C 10 alkyl, C 2 -C 10 -alkenyl, C 2 -C 10 -alkynyl, C 1 -C 5 -alkyl-C 3 -C 6 cycloalkyl, (C 1 -C y)-O-(C 1 -C x) and (C 1 -C y)-S-(C 1 -C x), wherein y and x each represent an integer in the range of 0-7 and wherein y+x≤7, each moiety optionally being substituted with 1-3 substituents independently selected from halo, C 1 -C 6 alkyl, C 3 -C 6 cylcoalkyl, phenyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy and CH 2 -O-C 1 -C 6 alkyl - an aromatic moiety selected from the group consisting of phenyl and naphtyl, each optionally substituted with 1-3 substituents independently selected from halo, C 1 -C 6 alkyl, C 3 -C 6 cylcoalkyl, phenyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy and CH 2 -O-C 1 -C 6 alkyl; or - a heteroaromatic moiety selected from the group consisting of thienyl, benzothienyl, furyl, benzopyranyl, pyrol, indolyl, pyran, pyrimidine, triazine, pyridyl, quinolyl, isoquinolyl, isoxazole, oxazole, pyrazole, thiazole, imidazole, triazole, oxadiazole, thiadiazole and tetrazole, each optionally substituted with 1-3 substituents independently selected from halo, C 1 -C 6 alkyl, C 3 -C 6 cylcoalkyl, phenyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy and CH 2 -O-C 1 -C 6 alkyl. - an aliphatic or heteroaliphatic moiety selected from the group consisting of C 1 -C 10 alkyl, C 2 -C 10 -alkenyl, C 2 -C 10 -alkynyl, C 1 -C 5 -alkyl-C 3 -C 6 cycloalkyl, (C 1 -C y)-O-(C 1 -C x) and (C 1 -C y)-S-(C 1 -C x), wherein y and x each represent an integer in the range of 0-7 and wherein y+x≤7, each moiety optionally being substituted with 1-3 substituents independently selected from halo, C 1 -C 6 alkyl, C 3 -C 6 cylcoalkyl, phenyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy and CH 2 -O-C 1 -C 6 alkyl - an aromatic moiety selected from the group consisting of phenyl and naphtyl, each optionally substituted with 1-3 substituents independently selected from halo, C 1 -C 6 alkyl, C 3 -C 6 cylcoalkyl, phenyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy and CH 2 -O-C 1 -C 6 alkyl; or - a heteroaromatic moiety selected from the group consisting of thienyl, benzothienyl, furyl, benzopyranyl, pyrol, indolyl, pyran, pyrimidine, triazine, pyridyl, quinolyl, isoquinolyl, isoxazole, oxazole, pyrazole, thiazole, imidazole, triazole, oxadiazole, thiadiazole and tetrazole, each optionally substituted with 1-3 substituents independently selected from halo, C 1 -C 6 alkyl, C 3 -C 6 cylcoalkyl, phenyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy and CH 2 -O-C 1 -C 6 alkyl.