mhurhangee/ep-ind-claims huggingface dataset:
A compound of Formula, or a pharmaceutically acceptable salt, or solvate thereof: wherein Y is A is phenyl; n is 1; R 1 is selected from hydrogen, halo, C 1-6 alkyl, C 1-6 haloalkyl, C 1-6 alkoxy and cyano; and either: - R 2 is selected from halo, C 1-6 alkyl, C 1-6 haloalkyl, and C 1-6 alkoxy, and - R 3 is selected from hydrogen, halo, C 1-6 alkyl, C 1-6 haloalkyl, and C 1-6 alkoxy; or - R 2 is selected from hydrogen, halo, C 1-6 alkyl, C 1-6 haloalkyl, and C 1-6 alkoxy, and - R 3 is selected from halo, C 1-6 alkyl, C 1-6 haloalkyl, and C 1-6 alkoxy; or - R 2 and R 3 together form a phenyl or 5-membered heterocyclyl. wherein Y is A is phenyl; n is 1; R 1 is selected from hydrogen, halo, C 1-6 alkyl, C 1-6 haloalkyl, C 1-6 alkoxy and cyano; - R 2 is selected from halo, C 1-6 alkyl, C 1-6 haloalkyl, and C 1-6 alkoxy, and - R 3 is selected from hydrogen, halo, C 1-6 alkyl, C 1-6 haloalkyl, and C 1-6 alkoxy; or - R 2 is selected from hydrogen, halo, C 1-6 alkyl, C 1-6 haloalkyl, and C 1-6 alkoxy, and - R 3 is selected from halo, C 1-6 alkyl, C 1-6 haloalkyl, and C 1-6 alkoxy; or - R 2 and R 3 together form a phenyl or 5-membered heterocyclyl.
A device for the detection and/or quantification of a target analyte in a sample, the device comprising: a) a lateral flow assay comprising a porous matrix; and b) an aqueous two-phase system (ATPS), disposed within said porous matrix, wherein the porous matrix is configured to and has porosity sufficient to allow the ATPS or components thereof to flow through the porous matrix when the ATPS or components thereof are in a fluid phase, wherein said porous LFA device is a paper fluidic device and wherein the ATPS can phase separate as the solution flows through the paper. a) a lateral flow assay comprising a porous matrix; and b) an aqueous two-phase system (ATPS), disposed within said porous matrix, wherein the porous matrix is configured to and has porosity sufficient to allow the ATPS or components thereof to flow through the porous matrix when the ATPS or components thereof are in a fluid phase,
A self-expanding, flexible intravascular stent for use in a vessel, having two or more annular segments (2, 2a) connected axially to each other, each formed of a plurality of struts (5, 5a) connected to each other in a serpentine manner by means of bends, AM wherein the stent has a crimped state having a reduced diameter and an expanded state having a nominal diameter, and the annular segments (2, 2a) comprise a first expansion characteristic in a first diameter range smaller than the nominal diameter, and comprise a second expansion characteristic, different from the first expansion characteristic, in a second diameter range greater than the nominal diameter, characterized in that a radial force-diameter profile of the stent, starting from the crimped state to the expanded state, takes the following course: firstly, in a first diameter range, a decrease in slope followed by an increase in slope, then when transitioning into the second diameter range, another decrease in slope and preferably finally another increase in slope. two or more annular segments (2, 2a) connected axially to each other, each formed of a plurality of struts (5, 5a) connected to each other in a serpentine manner by means of bends, AM wherein the stent has a crimped state having a reduced diameter and an expanded state having a nominal diameter, and the annular segments (2, 2a) comprise a first expansion characteristic in a first diameter range smaller than the nominal diameter, and comprise a second expansion characteristic, different from the first expansion characteristic, in a second diameter range greater than the nominal diameter, characterized in that a radial force-diameter profile of the stent, starting from the crimped state to the expanded state, takes the following course: firstly, in a first diameter range, a decrease in slope followed by an increase in slope, then when transitioning into the second diameter range, another decrease in slope and preferably finally another increase in slope.
A coupling element for connecting two frame profiles (2, 3) for window frames, façades or the like, having a sheet steel or aluminium part (10, 11) and having a seal (24, 25), the sheet steel or aluminium part (10, 11) having an undercut groove (22, 23) and the seal (24, 25) having a latching foot (26, 27), which is arranged in the undercut groove (22, 23), characterised in that the seal (24, 25) has a sealing region (28, 29) having a groove (30, 31), which fits over a web (32, 33) of the sheet steel or aluminium part (10, 11), which web can project into a frame profile (2, 3).
A key cylinder device, comprising: a cylindrical rotor case; a rotor rotatably enclosed in the rotor case; a sleeve fixedly disposed between the rotor and the rotor case; and a tumbler moving in a radial direction inside the rotor by insertion and extraction of a mechanical key into and from the rotor and comprising two half tumblers, wherein the sleeve comprises a hole not engaged with the tumbler by the insertion of the mechanical key and engaged by the extraction of the mechanical key, and a dividing wall formed at a middle of the hole, the dividing wall receiving one of the half tumblers on each side of said wall, and wherein a part of the dividing wall is engaged with a recessed groove formed on an inner peripheral surface of the rotor case, wherein the dividing wall and the recessed groove define an illegal rotation preventing portion that prevents the sleeve from moving beyond a predetermined position and from rotating together with the rotor. a cylindrical rotor case; a rotor rotatably enclosed in the rotor case; a sleeve fixedly disposed between the rotor and the rotor case; and a tumbler moving in a radial direction inside the rotor by insertion and extraction of a mechanical key into and from the rotor and comprising two half tumblers, wherein the sleeve comprises a hole not engaged with the tumbler by the insertion of the mechanical key and engaged by the extraction of the mechanical key, and a dividing wall formed at a middle of the hole, the dividing wall receiving one of the half tumblers on each side of said wall, and wherein a part of the dividing wall is engaged with a recessed groove formed on an inner peripheral surface of the rotor case, wherein the dividing wall and the recessed groove define an illegal rotation preventing portion that prevents the sleeve from moving beyond a predetermined position and from rotating together with the rotor.
Method for coating a pulp honeycomb composite support part having a plurality of channels which extend in an axial direction with an impregnating coating for increasing the refractoriness and/or the watertightness and/or the mechanical stability, wherein an impregnating agent is fed into a vacuum coating chamber and a complete and axially continuous coating is generated in the channels on their inner circumferential areas through deposition of the impregnating agent on the inner circumferential areas of the channels, and the excess impregnating agent is removed from the vacuum coating chamber, characterised in that the honeycomb composite support part and the vacuum coating chamber move relative to each other.
A computer-implemented method of pseudo-randomly selecting game elements for use in playing a game, wherein the game is played by a set of users, wherein the game elements are used to determine an outcome of the game, and wherein the method is performed by an oracle and comprises: obtaining a set of seed data items, wherein the set of seed data items comprises one or more user seed data items generated by a respective user; obtaining a sequence of public keys; obtaining a list of game elements, wherein a total number of public keys corresponds to a total number of game elements; and generating a first output of a game transaction, wherein the game transaction is a blockchain transaction, wherein the first output comprises the sequence of public keys, and wherein the output comprises a script configured to generate at least one pseudorandom number, the at least one pseudorandom number being based on the set of seed data items, wherein the script is configured to generate a list of the public keys based on the at least one pseudorandom number, and wherein an order of public keys in the list of public keys differs compared to an order of public keys in the sequence of public keys. obtaining a set of seed data items, wherein the set of seed data items comprises one or more user seed data items generated by a respective user; obtaining a sequence of public keys; obtaining a list of game elements, wherein a total number of public keys corresponds to a total number of game elements; and generating a first output of a game transaction, wherein the game transaction is a blockchain transaction, wherein the first output comprises the sequence of public keys, and wherein the output comprises a script configured to generate at least one pseudorandom number, the at least one pseudorandom number being based on the set of seed data items, wherein the script is configured to generate a list of the public keys based on the at least one pseudorandom number, and wherein an order of public keys in the list of public keys differs compared to an order of public keys in the sequence of public keys.
Image information assessment method in which a multiplicity of ACTUAL individual images (I-EB) or ACTUAL videos (I-VD) are recorded from a vehicle, in a manner relatively positioned with respect to, preferably behind, a vehicle window, in particular a windscreen, side window and/or rear window, characterized in that a) a multiplicity of TARGET individual images (S-EB) or TARGET videos (S-VD) are recorded from positions and/or movements of distinctive vehicle window components (FZSK), e.g. those having markings, in particular distinctive, e.g. artificially marked, windscreen wipers (WSSW) and/or rear window wipers, and from the same vehicle-specific relative position with respect to the vehicle window as in the case of the ACTUAL individual image/ACTUAL video capture, b) for reported positions (POS FZSK) of the vehicle window components (FZSK, WSSW, HSW) and for the purpose of image assessment in respect of quality or merit, the ACTUAL individual images (I-EB) are compared with the TARGET individual images (S-EB) or respectively the ACTUAL videos (I-VD) are compared with the TARGET videos (S-VD) wherein the ACTUAL individual images (I-EB) or respectively ACTUAL videos (I-VD) are assessed in respect of quality or merit (BW Q, G) depending on how well at least distinctive points, in particular the markings, of the vehicle window components (FZSK, WSSW, HSW) can be recognized at TARGET positions defined for the reported positions (POS FZSK) by the comparison. a) a multiplicity of TARGET individual images (S-EB) or TARGET videos (S-VD) are recorded from positions and/or movements of distinctive vehicle window components (FZSK), e.g. those having markings, in particular distinctive, e.g. artificially marked, windscreen wipers (WSSW) and/or rear window wipers, and from the same vehicle-specific relative position with respect to the vehicle window as in the case of the ACTUAL individual image/ACTUAL video capture, b) for reported positions (POS FZSK) of the vehicle window components (FZSK, WSSW, HSW) and for the purpose of image assessment in respect of quality or merit, the ACTUAL individual images (I-EB) are compared with the TARGET individual images (S-EB) or respectively the ACTUAL videos (I-VD) are compared with the TARGET videos (S-VD) wherein the ACTUAL individual images (I-EB) or respectively ACTUAL videos (I-VD) are assessed in respect of quality or merit (BW Q, G) depending on how well at least distinctive points, in particular the markings, of the vehicle window components (FZSK, WSSW, HSW) can be recognized at TARGET positions defined for the reported positions (POS FZSK) by the comparison.
A pharmaceutical formulation for oral administration in a form of a film coated tablet which is obtainable by direct compression of the tablet core and which comprises (a) levocetirizine or a pharmaceutically acceptable salt thereof, mixed together with (b) montelukast or a pharmaceutically acceptable salt thereof, where (a) and (b) are placed together in the tablet core and wherein the content of montelukast impurity C of formula is not higher than 0.5% based on nominal montelukast content when the tablet is stored at 40°C±2°C and 75%±5% relative humidity for 6 months. (a) levocetirizine or a pharmaceutically acceptable salt thereof, mixed together with (b) montelukast or a pharmaceutically acceptable salt thereof,
Device for closing a container forming a reservoir, of the type comprising: - a connecting member having an external thread and intended to be carried by the container, - a cap having an internal thread and intended to be placed on the connecting member or to be removed from this connecting member by screwing or unscrewing, - safety means comprising: - at least one circumferential locking stop carried by the cap, and - at least one complementary retractable circumferential locking stop carried by the connecting member, the connecting member comprises - a body of generally annular shape, - a radial arm provided with a free end and an end for connecting with the body, the free end of the radial arm being movable in at least one axial component by elastic deformation of this radial arm, - a radial forearm, - a lug carried by the radial forearm, this lug forming the complementary retractable circumferential locking stop, characterised in that the forearm is provided with a free end and an end for connecting with the free end of the radial arm so that the radial forearm and the radial arm each extend from their connecting end (44, 50) to their free end (42, 48) in opposite directions. - a connecting member having an external thread and intended to be carried by the container, - a cap having an internal thread and intended to be placed on the connecting member or to be removed from this connecting member by screwing or unscrewing, - safety means comprising: - at least one circumferential locking stop carried by the cap, and - at least one complementary retractable circumferential locking stop carried by the connecting member, - at least one circumferential locking stop carried by the cap, and - at least one complementary retractable circumferential locking stop carried by the connecting member, - a body of generally annular shape, - a radial arm provided with a free end and an end for connecting with the body, the free end of the radial arm being movable in at least one axial component by elastic deformation of this radial arm, - a radial forearm, - a lug carried by the radial forearm, this lug forming the complementary retractable circumferential locking stop,
An identifying device of a dialyzer apparatus or a component thereof, wherein the component is a membrane filter device, wherein the dialyzer apparatus and/or a membrane filter device disposed thereon or in it comprises a passive or active identification unit that comprises an identification feature that is characteristic for the identification of the dialyzer apparatus and/or the membrane filter device, wherein the identifying device comprises a sensor device, and characterized in that the sensor device is designed as a clip unit having at least one flexible clip arm or clip cuff adapted for reading the identification features included in the identification unit and therefor may be directly connected in a removable fashion to a housing of the dialyzer apparatus or the membrane filter device and that comprises a signal receiving unit (210, 212, 220, 222, 224) that is designed to receive at least one signal from the housing, from the outside or edge region of the housing, or from the internal volume portion of the housing, wherein the dialyzer apparatus or the membrane filter device is designed such that the sensor device can detect or measure such a signal which is, corresponding to the identification features, characteristic for the dialyzer apparatus or the membrane filter device, such that an identification of the dialyzer apparatus or the membrane filter device may occur, and wherein the identifying device further comprises an analysis unit that is designed to generate data on the basis of the received signal that may be used for identification or for identification and controlling the operating parameters of a dialysis machine.
A polypeptide comprising a first fragment and a second fragment, wherein (i) the first fragment is a toxin A repeating domain fragment and comprises at least 100 amino acids; (ii) the second fragment is a toxin B repeating domain fragment and comprises at least 100 amino acids; (iii) the proximal end of the first fragment is located within a first repeat portion; (iv) the proximal end of the second fragment is located within a second repeat portion; and wherein the first fragment and the second fragment are separated by less than or exactly 5 amino acids in the primary structure, wherein the polypeptide elicits antibodies that neutralise toxin A and toxin B and wherein the first repeat portion and the second repeat portion have greater than 50% sequence identity to one another. (i) the first fragment is a toxin A repeating domain fragment and comprises at least 100 amino acids; (ii) the second fragment is a toxin B repeating domain fragment and comprises at least 100 amino acids; (iii) the proximal end of the first fragment is located within a first repeat portion; (iv) the proximal end of the second fragment is located within a second repeat portion; and
Method for obtaining a modified collagen absorbent product from leather, characterized in that it comprises the steps of: - aerating flat leather pieces with a molecular structure during a time period between 15 and 45 days; - collecting the leather pieces with an initial relative humidity value of 45% or less; - grading the leather pieces by size; - obtaining the leather pieces with a maximum final length of between 0.5-1.5 mm, - placing the leather pieces in a drying oven; - applying heat in the drying oven so that the leather pieces are exposed to a temperature of between 120oC and 285°C during a time period, - controlling the temperature applied during the time period so that the relative humidity is reduced to a final value between 0.5-5% in the leather pieces; - reducing the temperature of leather pieces to an ambient temperature; - obtaining the modified collagen absorbent product from leather. - aerating flat leather pieces with a molecular structure during a time period between 15 and 45 days; - collecting the leather pieces with an initial relative humidity value of 45% or less; - grading the leather pieces by size; - obtaining the leather pieces with a maximum final length of between 0.5-1.5 mm, - placing the leather pieces in a drying oven; - applying heat in the drying oven so that the leather pieces are exposed to a temperature of between 120oC and 285°C during a time period, - controlling the temperature applied during the time period so that the relative humidity is reduced to a final value between 0.5-5% in the leather pieces; - reducing the temperature of leather pieces to an ambient temperature; - obtaining the modified collagen absorbent product from leather.
Method for operating a tyre pressure monitoring system which comprises tyre pressure monitoring units mounted in or on the tyres of a vehicle and a central evaluation unit, in which method tyre data from the tyre pressure monitoring units is sent in the form of data telegrams containing a preamble (0xFF, 0xF2), pressure information (P rel), temperature information and a characteristic identifier (ID1, ID2, ID3, ID4), and the pressure and temperature information of the data telegrams is assigned by the central evaluation unit to a wheel position on the vehicle, the pressure information (P rel) being sent in the data telegrams before the characteristic identifier (ID1, ID2, ID3, ID4), characterised in that the central evaluation unit evaluates incompletely received data telegrams and assigns them to a wheel position on the basis of an incomplete characteristic identifier or other data available to the central evaluation unit, and the central evaluation unit, when assigning an incompletely received data telegram, uses pressure information of other data telegrams which the central evaluation unit has assigned to one of the wheel positions of the vehicle to check to which tyre pressure monitoring units the pressure information (P rel) of the incompletely received data telegram belongs.
A method in a proxy cache apparatus of a Dynamic Adaptive Streaming over Hypertext transfer protocol, DASH, streaming system comprising the proxy cache apparatus, one or more serving network apparatuses and a streaming client apparatus, wherein the proxy cache apparatus stores one or more different representations of media content for a period of media content received from the one or more serving network apparatuses, the method comprising: receiving, in the proxy cache apparatus from the streaming client apparatus, a HTTP request including a first header field indicating acceptance of secondary representations by the streaming client apparatus; and, in response, transmitting a HTTP response message from the proxy cache apparatus to the streaming client apparatus in response to receiving the HTTP request, the HTTP response message comprising a second header field, wherein the HTTP response message is associated with a streaming description describing said one or more different representations of media content, and wherein the second header field includes a list of universal resource identifiers, URIs, for cached resources of said one or more different representations of the media content that are cached by the proxy cache apparatus. receiving, in the proxy cache apparatus from the streaming client apparatus, a HTTP request including a first header field indicating acceptance of secondary representations by the streaming client apparatus; and, in response, transmitting a HTTP response message from the proxy cache apparatus to the streaming client apparatus in response to receiving the HTTP request, the HTTP response message comprising a second header field, wherein the HTTP response message is associated with a streaming description describing said one or more different representations of media content, and wherein the second header field includes a list of universal resource identifiers, URIs, for cached resources of said one or more different representations of the media content that are cached by the proxy cache apparatus.
Apparatus for storing and launching at least one submersible body in a submarine, having an ejecting tube, in particular a torpedo tube, guided through the pressure hull of the submarine, having a load-bearing structure for storing and guiding the submersible body in the ejecting tube, and having means for launching the submersible body from the ejecting tube, wherein the load-bearing structure is of open design such that a space through which flow takes place essentially freely in a direction transverse to its longitudinal axis is formed between the ejecting tube and submersible body, and wherein the load-bearing structure has a longitudinal support, which is connected to at least two spaced-apart transverse supports, characterized in that the load-bearing structure has a guide which can be adapted to different submersible-body cross sections and of which the bearing and guide surfaces can be adjusted in relation to one another.