An autoclave for the sterilisation of sanitary waste and medical instruments, characterised in that it comprises: a main sterilising chamber configured for sterilizing medical instruments by pressurized steam; at least one female quick connection housed inside the main sterilising chamber that has a system of independent inlets and outlets which connect to the internal components of the autoclave; a second hermetic, exchangeable sterilising chamber configured to be housed inside the autoclave, said second hermetic exchangeable sterilising chamber having a male quick connection, which is configured to connect to the female quick connection inside the main sterilising chamber, wherein said second hermetic exchangeable sterilising chamber is configured to house waste; a third hermetic, exchangeable sterilising chamber configured to be housed inside the autoclave, said third hermetic, exchangeable sterilising chamber having a male quick connection, which is configured to connect to the female quick connection inside the main sterilising chamber and having a diameter smaller than a central shaft thereof so that the female quick-connection of the main sterilizing chamber detects presence of the male quick-connection through a diameter sensor present in the female quick-connection to indicate that the third hermetic, exchangeable sterilising chamber is present and wherein said third hermetic, exchangeable sterilising chamber is configured to carry out cold ozone sterilization; at least one ozone sterilisation system configured to connect to the second or third hermetic, exchangeable sterilising chamber; at least one moist heat sterilisation system configured to connect to the main sterilising chamber and the second hermetic, exchangeable sterilising chamber; at least one weight sensor, to weight the sanitary waste to be sterilised in the second sterilising chamber; and at least one electronic system configured to generate waste sterilisation reports. a main sterilising chamber configured for sterilizing medical instruments by pressurized steam; at least one female quick connection housed inside the main sterilising chamber that has a system of independent inlets and outlets which connect to the internal components of the autoclave; a second hermetic, exchangeable sterilising chamber configured to be housed inside the autoclave, said second hermetic exchangeable sterilising chamber having a male quick connection, which is configured to connect to the female quick connection inside the main sterilising chamber, wherein said second hermetic exchangeable sterilising chamber is configured to house waste; a third hermetic, exchangeable sterilising chamber configured to be housed inside the autoclave, said third hermetic, exchangeable sterilising chamber having a male quick connection, which is configured to connect to the female quick connection inside the main sterilising chamber and having a diameter smaller than a central shaft thereof so that the female quick-connection of the main sterilizing chamber detects presence of the male quick-connection through a diameter sensor present in the female quick-connection to indicate that the third hermetic, exchangeable sterilising chamber is present and wherein said third hermetic, exchangeable sterilising chamber is configured to carry out cold ozone sterilization; at least one ozone sterilisation system configured to connect to the second or third hermetic, exchangeable sterilising chamber; at least one moist heat sterilisation system configured to connect to the main sterilising chamber and the second hermetic, exchangeable sterilising chamber; at least one weight sensor, to weight the sanitary waste to be sterilised in the second sterilising chamber; and at least one electronic system configured to generate waste sterilisation reports.