A surgical clip applier, comprising: a housing; at least one handle pivotably connected to the housing; a channel assembly extending distally from the housing; a clip carrier disposed within the channel assembly and defining a channel therein; a plurality of clips slidably disposed within the channel of the clip carrier; a jaw assembly including a pair of jaws extending from an end of the channel assembly, opposite the housing, the jaw assembly configured to accommodate a clip therein and being operable to effect formation of the clip in response to movement of the at least one handle; a clip pusher bar slidably supported within at least one of the housing and the channel assembly, the clip pusher bar having a first end operatively connected to the at least one handle; and a camming plate slidably supported within the channel assembly and configured to effectuate closure of the pair of jaws, the camming plate including a lost motion portion, the lost motion portion of the camming plate includes a shoulder; characterised in that the clip pusher bar comprises at least one flexible tab which is distally oriented and inwardly biased against the lost motion portion of the camming plate, the at least one flexible tab being configured to: engage the shoulder of the lost motion portion of the camming plate, during an initial movement of the clip pusher bar in the distal direction, to cause the camming plate to move distally with the clip pusher bar; and be disengaged from the shoulder of the lost motion portion of the camming plate, during a subsequent movement of the clip pusher bar in the distal direction, to allow the clip pusher bar to move in the distal direction relative to the camming plate. a housing; at least one handle pivotably connected to the housing; a channel assembly extending distally from the housing; a clip carrier disposed within the channel assembly and defining a channel therein; a plurality of clips slidably disposed within the channel of the clip carrier; a jaw assembly including a pair of jaws extending from an end of the channel assembly, opposite the housing, the jaw assembly configured to accommodate a clip therein and being operable to effect formation of the clip in response to movement of the at least one handle; a clip pusher bar slidably supported within at least one of the housing and the channel assembly, the clip pusher bar having a first end operatively connected to the at least one handle; and a camming plate slidably supported within the channel assembly and configured to effectuate closure of the pair of jaws, the camming plate including a lost motion portion, the lost motion portion of the camming plate includes a shoulder; characterised in that the clip pusher bar comprises at least one flexible tab which is distally oriented and inwardly biased against the lost motion portion of the camming plate, the at least one flexible tab being configured to: engage the shoulder of the lost motion portion of the camming plate, during an initial movement of the clip pusher bar in the distal direction, to cause the camming plate to move distally with the clip pusher bar; and be disengaged from the shoulder of the lost motion portion of the camming plate, during a subsequent movement of the clip pusher bar in the distal direction, to allow the clip pusher bar to move in the distal direction relative to the camming plate. engage the shoulder of the lost motion portion of the camming plate, during an initial movement of the clip pusher bar in the distal direction, to cause the camming plate to move distally with the clip pusher bar; and be disengaged from the shoulder of the lost motion portion of the camming plate, during a subsequent movement of the clip pusher bar in the distal direction, to allow the clip pusher bar to move in the distal direction relative to the camming plate.