mhurhangee/ep-ind-claims huggingface dataset:
Eye examination apparatus comprising: - at least an illuminator adapted to project a light beam in an eye to illuminate a portion of the retina, said light beam being shaped to form a line of light that extends along a main axis of extension, when said light beam intersects the retina; - scanning means adapted to perform optical scans of the retina by cyclically moving the light beam projected by said illuminator on the retina along a scanning direction substantially perpendicular to the main axis of extension of said line of light; - an image sensor having a bi-dimensional surface adapted to receive light (2, 202) reflected by the retina and to acquire images of the retina; - separation means of the light beams adapted to separate the light projected by said illuminator from the light reflected by the retina and directed toward said image sensor; - a control unit adapted to control the operation of said scanning apparatus; characterized in that, in operation, in order to acquire each single image of a region of the retina to be framed, said image sensor is configured to integrate light (2, 202) reflected by the retina during at least two complete optical scans of said region of the retina by said scanning means. - at least an illuminator adapted to project a light beam in an eye to illuminate a portion of the retina, said light beam being shaped to form a line of light that extends along a main axis of extension, when said light beam intersects the retina; - scanning means adapted to perform optical scans of the retina by cyclically moving the light beam projected by said illuminator on the retina along a scanning direction substantially perpendicular to the main axis of extension of said line of light; - an image sensor having a bi-dimensional surface adapted to receive light (2, 202) reflected by the retina and to acquire images of the retina; - separation means of the light beams adapted to separate the light projected by said illuminator from the light reflected by the retina and directed toward said image sensor; - a control unit adapted to control the operation of said scanning apparatus;
A valve for connecting an external tank to an aircraft, the valve comprising: a valve body; and a seal assembly arranged, in use, to resiliently engage a seal surface on an aircraft, the seal assembly comprising: a telescopic seal member extending from a proximal end within the valve body to a distal end, the telescopic seal member being constrained within the valve body so as to maintain axial alignment of the telescopic seal member and the valve body; and a seal carrier characterised in that is provided at the distal end of the telescopic seal member, the seal carrier being pivotable relative to the telescopic seal member for alignment, in use, with the aircraft seal surface. a valve body; and a seal assembly arranged, in use, to resiliently engage a seal surface on an aircraft, the seal assembly comprising: a telescopic seal member extending from a proximal end within the valve body to a distal end, the telescopic seal member being constrained within the valve body so as to maintain axial alignment of the telescopic seal member and the valve body; and a seal carrier characterised in that is provided at the distal end of the telescopic seal member, the seal carrier being pivotable relative to the telescopic seal member for alignment, in use, with the aircraft seal surface. a telescopic seal member extending from a proximal end within the valve body to a distal end, the telescopic seal member being constrained within the valve body so as to maintain axial alignment of the telescopic seal member and the valve body; and a seal carrier characterised in that is provided at the distal end of the telescopic seal member, the seal carrier being pivotable relative to the telescopic seal member for alignment, in use, with the aircraft seal surface.
A fusion polypeptide comprising a target polypeptide and a tag polypeptide, wherein the tag polypeptide is present on a N-terminal side and/or a C-terminal side of the target polypeptide, and the tag polypeptide comprises a structure represented by Xaa-Cys-Zaa, i) Xaa being Asp or Glu, and Zaa being Asp or Glu; or ii) Xaa being Lys or Arg, and Zaa being Lys or Arg, and wherein the target polypeptide is an antibody or an antibody fragment,and wherein the antibody fragment is an Fab of the antibody, an Fab' of the antibody, a heavy chain of the antibody or a light chain of the antibody. i) Xaa being Asp or Glu, and Zaa being Asp or Glu; or ii) Xaa being Lys or Arg, and Zaa being Lys or Arg, and wherein the target polypeptide is an antibody or an antibody fragment,and wherein the antibody fragment is an Fab of the antibody, an Fab' of the antibody, a heavy chain of the antibody or a light chain of the antibody.
A valveless spacer device for an MDI, the spacer device comprising: a body having an inlet comprising a mount defining an inlet passage for sealingly engaging with a mouthpiece of an MDI and an outlet opposed from the inlet in which the outlet comprises a mouthpiece defining an outlet passage; 5 a demountable, flexible bag attached to the body, the bag and body together defining a chamber, such that the inlet and outlet are in fluid flow communication with an interior of the chamber; wherein the inlet is configured to be connected to an MDI containing a drug to be inhaled; wherein the outlet is configured to be received by a user's mouth; and wherein the flexible bag, following actuation of the MDI, serves as a reservoir allowing for the formation of a cloud or mist of the drug therewithin which is then ready for inhalation, the flexible bag being configured to be at least partially deflatable and at least partially inflatable commensurate with a single breath and/or rebreathing; characterized in that the body is in the form of a generally V-shaped mounting which is formed by the opposing inlet passage and the outlet passage intersecting at an angle along their respective longitudinal axes. a body having an inlet comprising a mount defining an inlet passage for sealingly engaging with a mouthpiece of an MDI and an outlet opposed from the inlet in which the outlet comprises a mouthpiece defining an outlet passage; 5 a demountable, flexible bag attached to the body, the bag and body together defining a chamber, such that the inlet and outlet are in fluid flow communication with an interior of the chamber; wherein the inlet is configured to be connected to an MDI containing a drug to be inhaled; wherein the outlet is configured to be received by a user's mouth; and wherein the flexible bag, following actuation of the MDI, serves as a reservoir allowing for the formation of a cloud or mist of the drug therewithin which is then ready for inhalation, the flexible bag being configured to be at least partially deflatable and at least partially inflatable commensurate with a single breath and/or rebreathing; characterized in that the body is in the form of a generally V-shaped mounting which is formed by the opposing inlet passage and the outlet passage intersecting at an angle along their respective longitudinal axes.
A riding lawn mower having an indicator system and a computer system that is configured to determine an occurrence of a predefined condition, wherein the indicator system is configured to communicate with the computer system, wherein the lawn mower further comprises: a display screen; and an illuminating element (105, 605) corresponding to the display screen, wherein the display screen is located proximate to the illuminating element (105, 605) wherein the computer system is configured to, upon detection of an occurrence of a particular predefined condition, illuminate the illuminating element (105, 605) in a particular manner based on the particular predefined condition and display visual information about the particular predefined condition on the display screen while the illuminating element (105, 605) is illuminated in the particular manner, wherein the illuminating element (105, 605) is capable of lighting in a plurality of different colors, each color being associated with a different predefined condition or type of condition, wherein a first color indicates a warning being displayed on the display screen that requires attention, and a second color indicates that information of a neutral type is being displayed on the display screen, wherein the illuminating element (105, 605) comprises a light source that surrounds a perimeter of the display screen. a display screen; and an illuminating element (105, 605) corresponding to the display screen, wherein the display screen is located proximate to the illuminating element (105, 605) wherein the computer system is configured to, upon detection of an occurrence of a particular predefined condition, illuminate the illuminating element (105, 605) in a particular manner based on the particular predefined condition and display visual information about the particular predefined condition on the display screen while the illuminating element (105, 605) is illuminated in the particular manner, wherein the illuminating element (105, 605) is capable of lighting in a plurality of different colors, each color being associated with a different predefined condition or type of condition, wherein a first color indicates a warning being displayed on the display screen that requires attention, and a second color indicates that information of a neutral type is being displayed on the display screen, wherein the illuminating element (105, 605) comprises a light source that surrounds a perimeter of the display screen.
A surgical device for stabilizing tissue or for positioning organs or for positioning and holding surgical instruments and devices during a surgical intervention, comprising a main body and a flexible arm, in particular an articulated arm, which in particular is or can be fastened to the main body, which can be brought into different positions and/or locations and which can be locked in a desired positioning by means of a tightening mechanism, the tightening mechanism being tightened and/or released self-actingly and/or by means of an energy source, characterized in that, in a locked state of the flexible arm, the tightening mechanism has a retightening reserve (ΔR), in particular a retightening reserve travel (ΔR), and the flexible arm can be automatically retightened in order to maintain its locked state, in particular by an introduction of energy from the energy source or self-actingly, by utilization of the retightening reserve (ΔR).
A turbomachine comprising a blade outer air seal assembly, the blade outer air seal assembly comprising: a blade outer air seal that is biased toward a second part, wherein the blade outer air seal and the second part move together radially during operation, and the blade outer air seal and the second part rotate relative to each other during operation of the turbomachine; and a supporting structure that supports the blade outer air seal, wherein the blade outer air seal is biased radially inwardly toward the second part with a pressurized fluid, characterised in that: radial inward movement of the blade outer air seal is limited exclusively by the second part during operation; and the supporting structure comprises a plurality of circumferential seals, wherein, during operation of the turbomachine, the blade outer air seal slides relative to the circumferential seals when biased by the pressurized fluid, and the seals are the only part of the supporting structure that contacts the blade outer air seal. a blade outer air seal that is biased toward a second part, wherein the blade outer air seal and the second part move together radially during operation, and the blade outer air seal and the second part rotate relative to each other during operation of the turbomachine; and a supporting structure that supports the blade outer air seal, wherein the blade outer air seal is biased radially inwardly toward the second part with a pressurized fluid, radial inward movement of the blade outer air seal is limited exclusively by the second part during operation; and the supporting structure comprises a plurality of circumferential seals, wherein, during operation of the turbomachine, the blade outer air seal slides relative to the circumferential seals when biased by the pressurized fluid, and the seals are the only part of the supporting structure that contacts the blade outer air seal.
An air data probe, comprising: a tapering probe tip portion having an inlet opening; a probe body extending from the tip portion and including a probe wall; a tube passage extending along an interior of the air data probe from the inlet opening to a tube end, the tube passage being bounded along its length by a tube inner surface that is offset a distance from a tube outer surface, the tube outer surface and the tube inner surface defining the probe wall having a wall thickness; and a heating element disposed within the tube passage, characterized by: the probe body being formed from a first material by direct energy metal deposition; and an insert being disposed in the probe wall, the insert being formed from a second material different from the first material, the second material having a thermal conductivity which is higher than that of the first material and being arranged to improve heat transfer rates from the heating element throughout the air data probe, and the insert being radially outward of the heating element and encapsulated in the wall via the direct energy metal deposition. a tapering probe tip portion having an inlet opening; a probe body extending from the tip portion and including a probe wall; a tube passage extending along an interior of the air data probe from the inlet opening to a tube end, the tube passage being bounded along its length by a tube inner surface that is offset a distance from a tube outer surface, the tube outer surface and the tube inner surface defining the probe wall having a wall thickness; and a heating element disposed within the tube passage, characterized by: the probe body being formed from a first material by direct energy metal deposition; and an insert being disposed in the probe wall, the insert being formed from a second material different from the first material, the second material having a thermal conductivity which is higher than that of the first material and being arranged to improve heat transfer rates from the heating element throughout the air data probe, and the insert being radially outward of the heating element and encapsulated in the wall via the direct energy metal deposition. the probe body being formed from a first material by direct energy metal deposition; and an insert being disposed in the probe wall, the insert being formed from a second material different from the first material, the second material having a thermal conductivity which is higher than that of the first material and being arranged to improve heat transfer rates from the heating element throughout the air data probe, and the insert being radially outward of the heating element and encapsulated in the wall via the direct energy metal deposition.
A method for guiding a robotic garden tool to a predetermined position, the robotic garden tool is provided with at least one sensing means adapted to detect a signal in a wire, the method comprising the steps wherein the robotic garden tool; detects a first signal from a first signal source, follows the first signal source at a varying distance to the first signal source, wherein the varying distance is a distance less than or equal to a maximum distance to the first signal source, wherein the maximum distance of the robotic garden tool from the first signal source is based on the strength of the detected first signal; detects a second signal from a second signal source, and follows the first signal source at a varying distance from the first signal source that is less than or equal to the maximum distance from the first signal source, wherein the maximum distance to the first signal source is set based at least in part on the detection of the second signal from the second signal source.
A method for operating a modular test bench, the modular test bench comprising at least one test module to test a test object, comprising: Receiving a first information on a hardware revision and on a software revision of the test module and receiving a second information on a hardware revision and on a software revision of the test object; Determining, if the combination of the first information and the second information fulfills a predetermined criterion; and Outputting a check signal, enabling the use of the test bench if the combination of the first information and the second information fulfill the predetermined criterion, wherein the predetermined criterion is fulfilled if the combination of the first information and the second information is present in a dataset comprising interoperable combinations between hardware revisions and software revisions of the test module and hardware revisions and software revisions of the test object. Receiving a first information on a hardware revision and on a software revision of the test module and receiving a second information on a hardware revision and on a software revision of the test object; Determining, if the combination of the first information and the second information fulfills a predetermined criterion; and Outputting a check signal, enabling the use of the test bench if the combination of the first information and the second information fulfill the predetermined criterion, wherein the predetermined criterion is fulfilled if the combination of the first information and the second information is present in a dataset comprising interoperable combinations between hardware revisions and software revisions of the test module and hardware revisions and software revisions of the test object.
A method of making a methylene malonate monomer comprising: (a) reacting a dialkyl bis(hydroxymethyl) malonate composition in the presence of a suitable catalyst which is a zeolite to form a methylene malonate monomer; and (b) isolating the methylene malonate monomer, wherein the term "alkyl" also includes cycloalkyl (alicyclic) groups and substituted alkyls, the latter of which refers to alkyl moieties having substituents replacing a hydrogen on one or more carbons of the hydrocarbon backbone; wherein the suitable catalyst is in the form of a column through which the dialkyl bis(hydroxymethyl) malonate composition is passed and the catalyst column is heated to a wall temperature between 180°C and 250°C. (a) reacting a dialkyl bis(hydroxymethyl) malonate composition in the presence of a suitable catalyst which is a zeolite to form a methylene malonate monomer; and (b) isolating the methylene malonate monomer,
A device for measuring aerodynamic magnitudes intended to be placed transversally in a flow passage (12, 13) of a turbine engine comprising: - an upstream body having a profile of general cylindrical shape defining a leading edge; - a plurality of sensors including instrumentation lines and sensitive elements, the instrumentation lines of the sensors being placed in the body, the sensitive elements of the sensors extending at the leading edge; - a downstream fairing mounted on the upstream body and defining a trailing edge; the device for measuring aerodynamic magnitude being characterized in that said downstream fairing comprises, in the longitudinal direction of the upstream body bearing the sensors, several sections of downstream fairing fixed independently of each other to the body, two successive sections being connected by a junction which in the longitudinal direction of the upstream body is more flexible than the sections. - an upstream body having a profile of general cylindrical shape defining a leading edge; - a plurality of sensors including instrumentation lines and sensitive elements, the instrumentation lines of the sensors being placed in the body, the sensitive elements of the sensors extending at the leading edge; - a downstream fairing mounted on the upstream body and defining a trailing edge;
A composition comprising recombinant human acid α-glucosidase (rhGAA) molecules for use in the treatment of Pompe disease in combination with miglustat in a patient in need thereof; wherein the patient is enzyme replacement therapy -experienced; wherein the composition is administered intravenously at a dose of 5 mg/kg to 20 mg/kg and the miglustat is administered orally at a dose of 260 mg or 130 mg; wherein the rhGAA molecules are produced in Chinese hamster ovary cells, the rhGAA molecules comprise seven potential N-glycosylation sites, 40%-60% of the N-glycans on the rhGAA molecules are complex type N-glycans, and at least 50% of the rhGAA molecules bear a bis-mannose-6-phosphate (bis-M6P) unit at the first potential N-glycosylation site. wherein the patient is enzyme replacement therapy -experienced; wherein the composition is administered intravenously at a dose of 5 mg/kg to 20 mg/kg and the miglustat is administered orally at a dose of 260 mg or 130 mg; wherein the rhGAA molecules are produced in Chinese hamster ovary cells, the rhGAA molecules comprise seven potential N-glycosylation sites, 40%-60% of the N-glycans on the rhGAA molecules are complex type N-glycans, and at least 50% of the rhGAA molecules bear a bis-mannose-6-phosphate (bis-M6P) unit at the first potential N-glycosylation site.
A method for preventing or inhibiting growth of a fungal pathogen of a plant, the method comprising: applying to the plant a compound of Formula I-B2: or an agriculturally acceptable salt thereof, wherein: one of Z 1 and Z 2 is NH-(CH 2) n -NR 4 R 5; and the other one of Z 1 and Z 2 is OH; or Z 1 = NH-(CH 2) n -NR 4 R 5; and Z 2 = Z 1; and wherein: R 5 is alkyl; R 4 is H or alkyl; n is an integer selected from 2 to 4; and M is 2H or a metal species; and exposing the plant to light. applying to the plant a compound of Formula I-B2: or an agriculturally acceptable salt thereof, wherein: one of Z 1 and Z 2 is NH-(CH 2) n -NR 4 R 5; and the other one of Z 1 and Z 2 is OH; or Z 1 = NH-(CH 2) n -NR 4 R 5; and Z 2 = Z 1; and wherein: R 5 is alkyl; R 4 is H or alkyl; n is an integer selected from 2 to 4; and M is 2H or a metal species; and one of Z 1 and Z 2 is NH-(CH 2) n -NR 4 R 5; and the other one of Z 1 and Z 2 is OH; Z 1 = NH-(CH 2) n -NR 4 R 5; and Z 2 = Z 1; R 5 is alkyl; R 4 is H or alkyl; n is an integer selected from 2 to 4; and M is 2H or a metal species; and exposing the plant to light.