A device for determining the concentration of an analyte in bodily fluids, said device comprising: a controller module comprising an actuator; a fluid handling device, comprising: a needle as a skin piercing element comprising a fluid collection channel; an inlet chamber connected to a first end of said skin piercing fluid collection channel; a pumping chamber; a connecting channel connecting said inlet chamber to an inlet end of said pumping chamber; a membrane connected to said actuator, said membrane forming a wall of said pumping chamber opposite said inlet end of said pumping chamber, said membrane being deflectable in response to movement of said actuator; a sensor chamber including a sensor for detecting said analyte; a pumping channel connecting an outlet end of said pumping chamber to an inlet end of said sensor chamber; a waste channel connected to an outlet end of said sensor chamber; and a vent connected to an outlet end of said waste channel, characterised in that the actuator comprises a pinching body and a spring-loaded pinching pin adapted to work with the pinching body, wherein the pinching pin is configured to deform the membrane to close the connecting channel and stop the flow of fluid from the inlet, and wherein further movement of the pinching body causes the membrane to be squeezed into the pumping chamber such that fluid is pumped along the pumping channel, wherein removing the pinching body causes fluid to be drawn back from the pumping channel into the pumping chamber while connecting channel is still closed by deformation of the pumping membrane by the pinching pin and wherein removing the pinching pin with further movement causes the connecting channel to open and to let fresh fluid into the pumping chamber, wherein the volume of fluid that is dispensed is at least as great as the combined volume of the connecting channel and the sensor. a controller module comprising an actuator; a fluid handling device, comprising: a needle as a skin piercing element comprising a fluid collection channel; an inlet chamber connected to a first end of said skin piercing fluid collection channel; a pumping chamber; a connecting channel connecting said inlet chamber to an inlet end of said pumping chamber; a membrane connected to said actuator, said membrane forming a wall of said pumping chamber opposite said inlet end of said pumping chamber, said membrane being deflectable in response to movement of said actuator; a sensor chamber including a sensor for detecting said analyte; a pumping channel connecting an outlet end of said pumping chamber to an inlet end of said sensor chamber; a waste channel connected to an outlet end of said sensor chamber; and a vent connected to an outlet end of said waste channel, characterised in that the actuator comprises a pinching body and a spring-loaded pinching pin adapted to work with the pinching body, wherein the pinching pin is configured to deform the membrane to close the connecting channel and stop the flow of fluid from the inlet, and wherein further movement of the pinching body causes the membrane to be squeezed into the pumping chamber such that fluid is pumped along the pumping channel, wherein removing the pinching body causes fluid to be drawn back from the pumping channel into the pumping chamber while connecting channel is still closed by deformation of the pumping membrane by the pinching pin and wherein removing the pinching pin with further movement causes the connecting channel to open and to let fresh fluid into the pumping chamber, wherein the volume of fluid that is dispensed is at least as great as the combined volume of the connecting channel and the sensor. a needle as a skin piercing element comprising a fluid collection channel; an inlet chamber connected to a first end of said skin piercing fluid collection channel; a pumping chamber; a connecting channel connecting said inlet chamber to an inlet end of said pumping chamber; a membrane connected to said actuator, said membrane forming a wall of said pumping chamber opposite said inlet end of said pumping chamber, said membrane being deflectable in response to movement of said actuator; a sensor chamber including a sensor for detecting said analyte; a pumping channel connecting an outlet end of said pumping chamber to an inlet end of said sensor chamber; a waste channel connected to an outlet end of said sensor chamber; and a vent connected to an outlet end of said waste channel,