mhurhangee/ep-ind-claims huggingface dataset:
A nucleoside phosphonate selected from the group of compounds having the following structures: wherein R is selected from the group consisting of -R 1 -O-R 2, wherein R 1 is selected from the group consisting of an optionally substituted C 1 to C 11 alkyl group and R 2 is selected from the group consisting of a C 6 to C 17 alkyl group or a C 6 to C 17 alkenyl group; wherein said C 6 to C 17 alkyl group is substituted with one or more alkyl groups so as to provide a branched chain alkyl group, which alkyl group is selected from the group consisting of methyl, ethyl and propyl, and /or said C 6 to C 17 alkyl group is substituted with one or more cycloalkyl groups, including cyclopropyl and/or said C 6 to C 17 alkyl group is substituted with one or more halogens selected from the group consisting of F, Cl, Br and I; provided that said C 6 to C 17 alkyl group includes one or more of said substituents at the terminal or penultimate position of the alkyl group or is branched at the terminal or penultimate position; and wherein said C 6 to C 17 alkenyl group is optionally-substituted with an alkyl group selected from the group consisting of methyl, ethyl, propyl, a cycloalkyl group including, cyclopropyl and/or one or more halogens selected from the group consisting of F, Cl, Br and I; and further wherein the said C 6 to C 17 alkenyl group contains one or more double bonds, including at least a terminal double bond; B is selected from a purine or pyrimidine base; and A is a counterion selected from the group consisting of H +, Li +, Na +, K +, NH 4 +, tetraalkyl ammonium and other tertiary amine salts including triethylamine. R is selected from the group consisting of -R 1 -O-R 2, wherein R 1 is selected from the group consisting of an optionally substituted C 1 to C 11 alkyl group and R 2 is selected from the group consisting of a C 6 to C 17 alkyl group or a C 6 to C 17 alkenyl group; said C 6 to C 17 alkyl group is substituted with one or more alkyl groups so as to provide a branched chain alkyl group, which alkyl group is selected from the group consisting of methyl, ethyl and propyl, and /or said C 6 to C 17 alkyl group is substituted with one or more cycloalkyl groups, including cyclopropyl and/or said C 6 to C 17 alkyl group is substituted with one or more halogens selected from the group consisting of F, Cl, Br and I; provided that said C 6 to C 17 alkyl group includes one or more of said substituents at the terminal or penultimate position of the alkyl group or is branched at the terminal or penultimate position; and said C 6 to C 17 alkenyl group is optionally-substituted with an alkyl group selected from the group consisting of methyl, ethyl, propyl, a cycloalkyl group including, cyclopropyl and/or one or more halogens selected from the group consisting of F, Cl, Br and I; and further wherein the said C 6 to C 17 alkenyl group contains one or more double bonds, including at least a terminal double bond; B is selected from a purine or pyrimidine base; and A is a counterion selected from the group consisting of H +, Li +, Na +, K +, NH 4 +, tetraalkyl ammonium and other tertiary amine salts including triethylamine.
A wireless device that distinguishes between multiple piconets, the wireless device comprising: a preamble component operable to provide a preamble for a wireless fixed frequency interleaving transmission; and a correlator component operable to distinguish a wireless transmission based on the preamble, wherein the preamble is based on a 128-length sequence formed by a 16-length sequence spread with a 8-length sequence, wherein the correlator component comprises a first spreader and a second spreader, and distinguishes the wireless transmission containing the preamble by spreading at least a portion of the wireless transmission with the 8-length sequence through the first spreader, and by spreading the output of the first spreader with the 16-length sequence through the second spreader, the output of the second spreader providing an indication of the presence of the preamble in the wireless transmission, wherein the 16-length sequence is selected from the group consisting of a first 16-length sequence, a second 16-length sequence, and a third 16-length sequence and the 8-length sequence is selected from the group consisting of a first 8-length sequence, a second 8-length sequence, and a third 8-length sequence. a preamble component operable to provide a preamble for a wireless fixed frequency interleaving transmission; and a correlator component operable to distinguish a wireless transmission based on the preamble, wherein the preamble is based on a 128-length sequence formed by a 16-length sequence spread with a 8-length sequence, wherein the correlator component comprises a first spreader and a second spreader, and distinguishes the wireless transmission containing the preamble by spreading at least a portion of the wireless transmission with the 8-length sequence through the first spreader, and by spreading the output of the first spreader with the 16-length sequence through the second spreader, the output of the second spreader providing an indication of the presence of the preamble in the wireless transmission, wherein the 16-length sequence is selected from the group consisting of a first 16-length sequence, a second 16-length sequence, and a third 16-length sequence and the 8-length sequence is selected from the group consisting of a first 8-length sequence, a second 8-length sequence, and a third 8-length sequence.
A method of producing a crystallized carotenoid-containing composition which is a needle crystal, wherein the maximum length of the crystals is 5 μm or longer, and whose astaxanthin content based on the total composition is 40 mass% or more, wherein the method comprises: an extraction step where a culture obtained by culturing a microorganism that produces carotenoids including astaxanthin is extracted using a one- to three-carbon alcohol; an extract separation step where an extract is obtained by separating the microorganism and the extract; a concentration step where a concentrate is obtained by concentrating the extract so that the liquid quantity of said extract is reduced to 1/1.25 to 1/20, and the astaxanthin concentration of the concentrate is 0.088 to 1.4% (wt/wt); a heating step, wherein the solution is heated to a temperature higher than the temperature for the crystallization step, thereby isomerizing at least one portion of cis-carotenoid isomers to trans-isomers; a crystallization step where crystals of the carotenoid-containing composition are produced in the concentrate; and a crystal separation step where the crystals are separated and obtained from mother liquor. an extraction step where a culture obtained by culturing a microorganism that produces carotenoids including astaxanthin is extracted using a one- to three-carbon alcohol; an extract separation step where an extract is obtained by separating the microorganism and the extract; a concentration step where a concentrate is obtained by concentrating the extract so that the liquid quantity of said extract is reduced to 1/1.25 to 1/20, and the astaxanthin concentration of the concentrate is 0.088 to 1.4% (wt/wt); a heating step, wherein the solution is heated to a temperature higher than the temperature for the crystallization step, thereby isomerizing at least one portion of cis-carotenoid isomers to trans-isomers; a crystallization step where crystals of the carotenoid-containing composition are produced in the concentrate; and a crystal separation step where the crystals are separated and obtained from mother liquor.
A train position detection apparatus that detects a position of a train by receiving positioning radio waves from satellites through a reception antenna, characterized by the train position detection apparatus comprising: a railway design standard storage unit configured to store therein in advance a railway design standard of a railway track on which the train travels, and includes a minimum curve radius, a relaxation curve, a slack, a cant, and a slope; the railway design standard being different depending on a travel speed of the train; and a position detection unit configured to detect a position of the train by self-contained navigation based on an input signal from a self-contained navigation sensor (13; 14; 15), wherein the position detection unit refers to a railway design standard corresponding to a detected travel speed of the train, and wherein, when a movement locus of the train obtained by position information based on the positioning radio waves does not satisfy the referred railway design standard, the position detection unit corrects the result of the train position detection based on the positioning radio waves with a result of the position detection by self-contained navigation. a railway design standard storage unit configured to store therein in advance a railway design standard of a railway track on which the train travels, and includes a minimum curve radius, a relaxation curve, a slack, a cant, and a slope; the railway design standard being different depending on a travel speed of the train; and a position detection unit configured to detect a position of the train by self-contained navigation based on an input signal from a self-contained navigation sensor (13; 14; 15), wherein the position detection unit refers to a railway design standard corresponding to a detected travel speed of the train, and wherein, when a movement locus of the train obtained by position information based on the positioning radio waves does not satisfy the referred railway design standard, the position detection unit corrects the result of the train position detection based on the positioning radio waves with a result of the position detection by self-contained navigation.
An ectophosphatase in combination with a disease-modifying anti-rheumatic drugs (DMARDS) for use in the treatment of a mammal suffering from arthritis, wherein the ectophosphatase is a tissue specific ectophosphatase selected from the group consisting of intestinal AP, placental ALP (PALP), preferably placental ALP (PALP) and said treatment is a chronic arthritis disease treatment.
Method for manufacturing a semiconductor component, comprising the steps: - providing at least one semiconductor module and a support frame, which has a respective opening for each of the semiconductor modules, - arranging the at least one semiconductor module on the support frame such that a base plate of the respective semiconductor module rests on the edge of the respective opening, - soldering the respective base plate to the support frame, wherein the respective base plate is soldered to the support frame with a solder that has a melting point of at least 450°C, characterized in that the soldering of the respective base plate to the support frame is performed by laser brazing, wherein the laser is hereby radiated onto that side of the support frame which faces away from the base plate, whereby the support frame is heated locally and the solder is melted by the heated support frame, wherein the material of the support frame is locally melted in the course of soldering the respective base plate to the support frame. - providing at least one semiconductor module and a support frame, which has a respective opening for each of the semiconductor modules, - arranging the at least one semiconductor module on the support frame such that a base plate of the respective semiconductor module rests on the edge of the respective opening, - soldering the respective base plate to the support frame, wherein the respective base plate is soldered to the support frame with a solder that has a melting point of at least 450°C,
A method of protecting a computing device from side channel attacks, comprising: performing in a processor of the computing device a behavior analysis operation to determine whether the computing device is vulnerable to side channel attacks; determining whether obfuscation is required in response to determining that the computing device is vulnerable to side channel attacks; and performing an obfuscation operation in response to determining that obfuscation is required, characterised in that: performing the behavior analysis operation to determine whether the computing device is vulnerable to side channel attacks comprises: monitoring an activity of the computing device; generating a behavior vector based on the monitored activity; and applying the generated behavior vector to a classifier model to determine whether the monitored activity is a critical activity. performing in a processor of the computing device a behavior analysis operation to determine whether the computing device is vulnerable to side channel attacks; determining whether obfuscation is required in response to determining that the computing device is vulnerable to side channel attacks; and performing an obfuscation operation in response to determining that obfuscation is required, characterised in that: performing the behavior analysis operation to determine whether the computing device is vulnerable to side channel attacks comprises: monitoring an activity of the computing device; generating a behavior vector based on the monitored activity; and applying the generated behavior vector to a classifier model to determine whether the monitored activity is a critical activity. performing the behavior analysis operation to determine whether the computing device is vulnerable to side channel attacks comprises: monitoring an activity of the computing device; generating a behavior vector based on the monitored activity; and applying the generated behavior vector to a classifier model to determine whether the monitored activity is a critical activity. monitoring an activity of the computing device; generating a behavior vector based on the monitored activity; and applying the generated behavior vector to a classifier model to determine whether the monitored activity is a critical activity.
Surgical instrument with a shaft and with a slide that is supported so as to be slideable on the shaft, wherein at least one guide element (6.1, 6.3), which is guided in at least one longitudinal groove (8.1, 8.3), is provided on the shaft and/or on the slide, and the shaft and/or the slide are/is respectively connected with a handle part (2, 4.1), wherein one handle part (4.1) of the handle parts (2, 4.1) is movable, relative to the other handle part, around a pivot joint (3.1) and has a slit which a cross bar of the slide engages in, wherein a position of the handle part (4.1) relative to the other handle part can be altered in a proximity of the pivot joint (3.1), wherein the pivot joint (3.1) connecting the two handle parts (2, 4.1) comprises a push button, from which a pin projects that passes through two congruent bores in the handle parts (2, 4.1), wherein a recess that is embodied as an oblong hole adjoins the bore in the movable handle part (4.1), characterised in that the pin is stepped in its diameter, the pin comprising pin elements (48.1, 48.2) with a larger diameter which are, in their normal position, situated in the bores of the movable handle part (4.1) and of the fixed handle part, the pin comprising a further pin element (48.3) with a smaller diameter, wherein the smaller diameter approximately corresponds to a width of the oblong hole.
Apparatus for inactivating renal nerve conduction in a mammalian subject comprising: a catheter adapted for insertion into a renal artery of the mammalian subject; an ultrasound transducer mounted to the catheter adjacent a distal end of the catheter, the ultrasound transducer adapted for insertion into the renal artery of the mammalian subject and for transmitting unfocused ultrasound energy; and an actuator electrically connected to the ultrasound transducer, the actuator being adapted to control the ultrasound transducer to transmit a therapeutic dose of unfocused ultrasound energy into an impact volume of at least 0.5 cm 3, encompassing the renal artery to inactivate conduction of renal nerves throughout the impact volume without causing damage to an intima of the renal artery; a balloon mounted at the distal end of the catheter, wherein the balloon is adapted to engage the wall of the renal artery, wherein, when inflated, the balloon centers the balloon within the renal artery and a liquid is deliverable to the balloon to cool the inner lining of the renal artery; and a machine-readable element affixed to the catheter, the machine readable element including information associated with an optimum actuation frequency. a catheter adapted for insertion into a renal artery of the mammalian subject; an ultrasound transducer mounted to the catheter adjacent a distal end of the catheter, the ultrasound transducer adapted for insertion into the renal artery of the mammalian subject and for transmitting unfocused ultrasound energy; and an actuator electrically connected to the ultrasound transducer, the actuator being adapted to control the ultrasound transducer to transmit a therapeutic dose of unfocused ultrasound energy into an impact volume of at least 0.5 cm 3, encompassing the renal artery to inactivate conduction of renal nerves throughout the impact volume without causing damage to an intima of the renal artery; a balloon mounted at the distal end of the catheter, wherein the balloon is adapted to engage the wall of the renal artery, wherein, when inflated, the balloon centers the balloon within the renal artery and a liquid is deliverable to the balloon to cool the inner lining of the renal artery; and a machine-readable element affixed to the catheter, the machine readable element including information associated with an optimum actuation frequency.
An isolated antibody or fragment thereof that is capable of binding to a complex comprising β-Klotho and FGFR1c and induces FGF21-mediated signaling and comprises the following CDRs: a) CDRH1: SEQ ID NO: 122; b) CDRH2: SEQ ID NO: 133; c) CDRH3: SEQ ID NO: 148; d) CDRL1: SEQ ID NO: 166; e) CDRL2: SEQ ID NO: 176; and f) CDRL3: SEQ ID NO: 188; for use in therapy. a) CDRH1: SEQ ID NO: 122; b) CDRH2: SEQ ID NO: 133; c) CDRH3: SEQ ID NO: 148; d) CDRL1: SEQ ID NO: 166; e) CDRL2: SEQ ID NO: 176; and f) CDRL3: SEQ ID NO: 188;
A lamp housing for receiving at least one lighting means, in particular at least one LED, with two housing parts (2, 3) in the form of extruded profiles, a first one of said housing parts having a base body with a bottom region and lateral regions extending from said bottom region, and the second housing part being arranged in a region remote from said bottom region and attached to said first housing part such that it covers an opening of said first housing part delimited by said lateral regions, wherein said first and second housing parts (2, 3) are attached to one another so as to form a snap connection which forms, at each of said lateral regions, a form-fitting connection between a holding surface of said lateral region and a contact surface of said second housing part, characterized in that said contact surfaces are located in a lateral edge region of said second housing part and a contact surface and a holding surface are in each case formed by a complementary pair of a cylinder segment-shaped protrusion extending in a longitudinal direction of the respective profile and a cylinder segment-shaped recess, and the respective cylinder segment defining the holding surface and the contact surface, respectively, is tilted (α) relative to the slip-on direction in which said second housing part is fitted onto the opening to be closed, or relative to said lateral regions, and that the contact surfaces are located on protrusions which are arranged in a lateral edge region of said second housing part and extend towards the bottom region of said first housing part, and that the holding surfaces are arranged at a distance from the free ends of said lateral regions.
A vehicle engine enclosure, comprising: an engine mounted on a tractor frame; a cooling system mounted on the frame, the cooling system having a housing surrounding cooling components; and a hood, the hood being mounted on the frame and enclosing the engine and the cooling system, the hood comprising atop panel and left and right hood side panels (16, 18), the top panel having a vent therein, characterized by a front seal which has an upper strip and side strips (44, 46) extending downwardly from upper strip, the upper strip forming a seal between the housing and the top panel; a pair of left and right side plates (24, 26) mounted on the frame; and each side strip (44, 46) sealing between one of the hood side panels (16, 18) and a corresponding one of the side plates (24, 26), curved side seal strips (48, 50), connected to side strips (44, 46) a pair of lower side seals (60, 62), each lower side seal (60, 62) sealing between the frame and a corresponding one of the side plates (24, 26), the side plates (24, 26), the hood, the frame, the engine and the cooling system cooperating to form a duct which collects hot air leaving the cooling system and moves it vertically away from the tractor to prevent re-ingesting of the hot air. an engine mounted on a tractor frame; a cooling system mounted on the frame, the cooling system having a housing surrounding cooling components; and a hood, the hood being mounted on the frame and enclosing the engine and the cooling system, the hood comprising atop panel and left and right hood side panels (16, 18), the top panel having a vent therein, characterized by a front seal which has an upper strip and side strips (44, 46) extending downwardly from upper strip, the upper strip forming a seal between the housing and the top panel; a pair of left and right side plates (24, 26) mounted on the frame; and each side strip (44, 46) sealing between one of the hood side panels (16, 18) and a corresponding one of the side plates (24, 26), curved side seal strips (48, 50), connected to side strips (44, 46) a pair of lower side seals (60, 62), each lower side seal (60, 62) sealing between the frame and a corresponding one of the side plates (24, 26), the side plates (24, 26), the hood, the frame, the engine and the cooling system cooperating to form a duct which collects hot air leaving the cooling system and moves it vertically away from the tractor to prevent re-ingesting of the hot air.