mhurhangee/ep-ind-claims huggingface dataset:
An electrosurgical lysing device, comprising: a lysing tip comprising: a non-conductive body; at least one bead, wherein the at least one bead comprises an at least substantially electrically non-conductive surface; and a nonconductive strut coupled with the at least one bead; wherein at least one distally-facing recess is defined between the at least one bead, the non-conductive strut and a distal portion of the non-conductive body, and at least one proximally-facing recess is defined between the at least one bead, the non-conductive strut and a proximal portion of the non-conductive body; a single shaft, wherein the lysing tip is positioned at a distal end of the shaft; and at least one electrically conductive lysing member positioned adjacent to the at least one bead and configured to deliver electrosurgical energy from the lysing tip; wherein the at least one lysing member defines at least one distally-facing lysing segment extending within the at least one distally-facing recess, and defines at least one proximally-facing lysing segment extending within the at least one proximally-facing recess; wherein the at least one proximally-facing lysing segment extends within only the proximally-facing recess or recesses on a single side of the shaft. a lysing tip comprising: a non-conductive body; at least one bead, wherein the at least one bead comprises an at least substantially electrically non-conductive surface; and a nonconductive strut coupled with the at least one bead; wherein at least one distally-facing recess is defined between the at least one bead, the non-conductive strut and a distal portion of the non-conductive body, and at least one proximally-facing recess is defined between the at least one bead, the non-conductive strut and a proximal portion of the non-conductive body; a single shaft, wherein the lysing tip is positioned at a distal end of the shaft; and at least one electrically conductive lysing member positioned adjacent to the at least one bead and configured to deliver electrosurgical energy from the lysing tip; wherein the at least one lysing member defines at least one distally-facing lysing segment extending within the at least one distally-facing recess, and defines at least one proximally-facing lysing segment extending within the at least one proximally-facing recess; wherein the at least one proximally-facing lysing segment extends within only the proximally-facing recess or recesses on a single side of the shaft.
Method of screening for the presence of prostate cancer in a subject, comprising: (a) contacting a biological sample from a subject with a reagent for detecting the level of expression of non-coding RNA (ncRNA) of SEQ ID NOs: 1 and/or 2 (PCAT1); and (b) detecting the level of expression of PCAT1 in said sample using an in vitro assay, wherein an increased level of expression of PCAT1 in said sample relative to the level in normal prostate cells is indicative of prostate cancer in said subject. (a) contacting a biological sample from a subject with a reagent for detecting the level of expression of non-coding RNA (ncRNA) of SEQ ID NOs: 1 and/or 2 (PCAT1); and (b) detecting the level of expression of PCAT1 in said sample using an in vitro assay, wherein an increased level of expression of PCAT1 in said sample relative to the level in normal prostate cells is indicative of prostate cancer in said subject.
A method of manufacturing an asphalt mixture consisting of bitumen, dried aggregates and undried recycled material, wherein the aggregates and recycled material are added to the bitumen, wherein the weight ratio of bitumen, aggregates and recycled material is determined by weighing the aggregates during the mixing process, wherein the respective mass G (m)(t) of the individual aggregates is determined by a mineral scale, wherein a sudden pressure increase is produced by the sudden evaporation of the water contained in the undried or partially dried recycling material characterised in that a continuous pressure measurement of the sudden pressure increase is carried out below the mineral scale and a pressure difference p ( u,i)( t) - p ( o,i)( t) is determined therefrom, wherein the pressure difference is determined to determine a correction value G ( k)( t) for the weighing of the aggregates and an effective weighing parameter G ( eff) is calculated therefrom according to the formula G eff → = G m t → + G k t → = G m t → + k A ∗ ∑ i p u i t − p o i t ̅ ∗ e z →, wherein the weighing of the aggregates during the mixing process is performed with the calculated effective weighing parameter. wherein the aggregates and recycled material are added to the bitumen, wherein the weight ratio of bitumen, aggregates and recycled material is determined by weighing the aggregates during the mixing process, wherein the respective mass G (m)(t) of the individual aggregates is determined by a mineral scale, wherein a sudden pressure increase is produced by the sudden evaporation of the water contained in the undried or partially dried recycling material characterised in that a continuous pressure measurement of the sudden pressure increase is carried out below the mineral scale and a pressure difference p ( u,i)( t) - p ( o,i)( t) is determined therefrom, wherein the pressure difference is determined to determine a correction value G ( k)( t) for the weighing of the aggregates and an effective weighing parameter G ( eff) is calculated therefrom according to the formula G eff → = G m t → + G k t → = G m t → + k A ∗ ∑ i p u i t − p o i t ̅ ∗ e z →, wherein the weighing of the aggregates during the mixing process is performed with the calculated effective weighing parameter.
A method, comprising: receiving, by a first computer system, a software stub from a second computer system; installing, by the first computer system, the received software stub; transmitting, by the software stub, a request for an executable code of a software program downloadable from the second computer system, the request comprising a URI, Uniform Resource Identifier, identifying the software program, receiving, by the software stub on the first computer system, the executable code of the software program in a data stream transmitted from the second computer system over a network connection between the first computer system and the second computer system; extracting, by the first computer system, the executable code of the software program received in the data stream from the second computer system; allocating, by the first computer system, an amount of dynamic memory for the executable code of the software program; loading, by the first computer system, the executable code of the software program extracted from the data stream directly into the allocated dynamic memory so that the executable code of the software program is not stored or installed on a permanent storage of the first computer system; and executing, by the first computer system, the software program by launching the executable code of the software program loaded in the allocated dynamic memory. receiving, by a first computer system, a software stub from a second computer system; installing, by the first computer system, the received software stub; transmitting, by the software stub, a request for an executable code of a software program downloadable from the second computer system, the request comprising a URI, Uniform Resource Identifier, identifying the software program, receiving, by the software stub on the first computer system, the executable code of the software program in a data stream transmitted from the second computer system over a network connection between the first computer system and the second computer system; extracting, by the first computer system, the executable code of the software program received in the data stream from the second computer system; allocating, by the first computer system, an amount of dynamic memory for the executable code of the software program; loading, by the first computer system, the executable code of the software program extracted from the data stream directly into the allocated dynamic memory so that the executable code of the software program is not stored or installed on a permanent storage of the first computer system; and executing, by the first computer system, the software program by launching the executable code of the software program loaded in the allocated dynamic memory.
A motor vehicle with at least a first driving wheel tilting with respect to a first rotation axis transverse to said vehicle and a second driving wheel tilting with respect to a second rotation axis transverse to said vehicle, said vehicle comprising a power source for generating power and a transmission for transmitting power to said first tilting driving wheel and second tilting driving wheel; said power source comprising separate and independent first electric motor and second electric motor, said transmission comprising two sections configured to transmit the power from said first electric motor to said first tilting driving wheel and respectively from said second electric motor to said second tilting driving wheel independently, and said vehicle comprising an electronic control unit adapted to receive and process one or more parameters and to control said first electric motor and second electric motor according to said one or more parameters, whereby the operation by the control unit of said first electric motor and/or second electric motor depending on said one or more parameters results in the transmission of power from said first electric motor and/or second motor to respectively said first titling driving wheel and/or second tilting driving wheel independently; wherein said two tilting driving wheels (R1, R2) are mechanically anchored to the chassis of said vehicle by means of a first anchoring arm (B 1) pivotable about said first rotation axis and a second anchoring arm pivotable about said second rotation axis, characterized in that said first driving wheel is also pivotable with respect to a first tilting axis longitudinal with respect to said vehicle, and in that said second driving wheel is also pivotable with respect to a second tilting axis longitudinal with respect to said vehicle.
A booster system for increasing pressure of an object gas to pressure equal to or higher than target pressure that is higher than critical pressure, comprising: a first compression unit that compresses the object gas to intermediate pressure equal to or higher than the critical pressure and lower than the target pressure to generate an intermediate supercritical fluid; a cooling unit that uses a cooling medium, and cools the intermediate supercritical fluid generated by the first compression unit to generate an intermediate supercritical pressure liquid; a liquid extracting and pressure reducing unit that extracts a part of the intermediate supercritical pressure liquid generated by the cooling unit; a first flow regulating valve that regulates a flow rate of the extracted part of the intermediate supercritical pressure liquid when supplied into the cooling unit, the extracted part of the intermediate supercritical pressure liquid serving as the cooling medium; and a second compression unit that increases pressure of the rest of the intermediate supercritical pressure liquid to a pressure equal to or higher than the target pressure; characterized by a first pressure sensor that detects pressure of the intermediate supercritical pressure liquid on an inlet side of the second compression unit, wherein an opening degree of the first flow regulating valve is regulated based on a detection result of the first pressure sensor. a first compression unit that compresses the object gas to intermediate pressure equal to or higher than the critical pressure and lower than the target pressure to generate an intermediate supercritical fluid; a cooling unit that uses a cooling medium, and cools the intermediate supercritical fluid generated by the first compression unit to generate an intermediate supercritical pressure liquid; a liquid extracting and pressure reducing unit that extracts a part of the intermediate supercritical pressure liquid generated by the cooling unit; a first flow regulating valve that regulates a flow rate of the extracted part of the intermediate supercritical pressure liquid when supplied into the cooling unit, the extracted part of the intermediate supercritical pressure liquid serving as the cooling medium; and a second compression unit that increases pressure of the rest of the intermediate supercritical pressure liquid to a pressure equal to or higher than the target pressure; characterized by a first pressure sensor that detects pressure of the intermediate supercritical pressure liquid on an inlet side of the second compression unit, wherein an opening degree of the first flow regulating valve is regulated based on a detection result of the first pressure sensor.
A method implemented in a wireless device (705, 800) for improving measurement of a reference signal parameter measured by a wireless device in a wireless communication network, the reference signal parameter being a parameter of a reference signal transmitted by a radio network node in the wireless communication network, the method comprising: determining that the wireless device is operating with a low measurement accuracy condition that affects measurement of the reference signal parameter, wherein a severity of the low measurement accuracy condition has a positive correlation with the quality of a channel over which the reference signal is received; adapting a first measurement bandwidth in response to determining that the wireless device has the low measurement accuracy condition that is positively correlated with the quality of the channel; measuring a first reference signal parameter using the adapted first measurement bandwidth; and modifying the measured first reference signal parameter to compensate for the low measurement accuracy condition by adding a compensation value to the measurement of the first reference signal parameter.
A firearm system comprising: a receiver complex including a receiver coupled to a forward receiver; a feed port positioned between the receiver and the forward receiver; a plurality of independently moveable firing pins; a striker coil assembly positioned proximate the receiver, the striker coil assembly including a plurality of electromagnetically moveable strikers and at least one striker coil, each electromagnetically movable striker extending at least partially through said coil and being positioned to strike one of the independently moveable firing pins when the striker is actuated, said at least one striker coil being configured to be powered by at least one current pulse from a power source of the firearm system, the at least striker coil being configured to electromagnetically actuate at least one striker of the plurality of electromagnetically moveable strikers; and a single barrel coupled to the forward receiver forming a breech, said single barrel comprising a barrel body including multiple bores through which a projectile can enter. a receiver complex including a receiver coupled to a forward receiver; a feed port positioned between the receiver and the forward receiver; a plurality of independently moveable firing pins; a striker coil assembly positioned proximate the receiver, the striker coil assembly including a plurality of electromagnetically moveable strikers and at least one striker coil, each electromagnetically movable striker extending at least partially through said coil and being positioned to strike one of the independently moveable firing pins when the striker is actuated, said at least one striker coil being configured to be powered by at least one current pulse from a power source of the firearm system, the at least striker coil being configured to electromagnetically actuate at least one striker of the plurality of electromagnetically moveable strikers; and a single barrel coupled to the forward receiver forming a breech, said single barrel comprising a barrel body including multiple bores through which a projectile can enter.
A vacuum cleaner comprising a removable cyclonic separator, the separator comprising: a cyclone chamber; a dirt-collection chamber, open at one end; an outlet duct from the cyclone chamber, an open end of the outlet duct being arranged for connection to a motor intake duct on the cleaner, the outlet duct and dirt collection chamber sharing a common wall section which divides the open end of the outlet duct from the open end of the dirt collection chamber; a cover which closes off the open end of the dirt collection chamber and which can be opened to allow access to the dirt collection chamber for emptying; and a cover sealing member which, when the cover is in the closed position, forms an air seal between the cover and the common wall section, characterised in that the separator further comprises an outlet duct sealing member which, when the outlet duct is connected to the motor inlet duct, forms an air seal between the ducts.
A breath-actuated inhalation device comprising an aerosol generator having a vibrator and a membrane, a reservoir (302,307) for liquid to be aerosolized which is in fluid communication with the membrane, and a controller that provides a driver signal to drive the vibrator so that the membrane vibrates and generates an aerosol, wherein the controller is configured to: • drive the vibrator intermittently so that the aerosol generator repeatedly undergoes periods of aerosol generation during a patient's inhalations and periods of little or no aerosol generation preceding and/or succeeding the inhalations; characterized in that the controller is further configured to: • perform scans in which the membrane is vibrated at a plurality of frequencies, and in which at least one electrical parameter of the vibrator is measured at the plurality of frequencies to provide a spectrum; wherein the scans are performed during the inhalations and during the periods preceding or succeeding the inhalations; • compare a spectrum obtained during an inhalation with a spectrum obtained during the period preceding or succeeding that inhalation; • determine whether liquid is present in the reservoir on the basis of the comparison of the spectra; and • cease to drive the vibrator if the controller determines that no liquid is present. • drive the vibrator intermittently so that the aerosol generator repeatedly undergoes periods of aerosol generation during a patient's inhalations and periods of little or no aerosol generation preceding and/or succeeding the inhalations; • perform scans in which the membrane is vibrated at a plurality of frequencies, and in which at least one electrical parameter of the vibrator is measured at the plurality of frequencies to provide a spectrum; wherein the scans are performed during the inhalations and during the periods preceding or succeeding the inhalations; • compare a spectrum obtained during an inhalation with a spectrum obtained during the period preceding or succeeding that inhalation; • determine whether liquid is present in the reservoir on the basis of the comparison of the spectra; and • cease to drive the vibrator if the controller determines that no liquid is present.
An implantable medical device comprising on all or part of its surface a layer comprising zirconia, said layer having a thickness of between about 50 and 2000 nm, wherein the layer comprises, in addition to zirconia, at least one element or compound comprising an element selected from Mg, Ca, Ag, and Zn, in particular in metallic or oxide form, located at least partially on the surface of the layer.
A protease consisting of an amino acid sequence of amino acids 14-384 of SEQ ID NO: 1 (xlAtg4B), wherein said protease is capable of cleaving the protease recognition site according to SEQ ID NO: 2 (xlLC3B) with at least 20% activity as compared to the parent protease with the amino acid sequence of SEQ ID NO: 1, if tested using a native substrate protein shown in SEQ ID NO: 3 (His 14 -xlLC3B-MBP) and 500 nM of said protease at standard conditions of 1 hour incubation at 0 °C, 100 μM initial concentration of substrate protein in a buffer consisting of 250 mM NaCl, 40 mM Tris/HCI pH 7.5, 2 mM MgCl 2, 250 mM sucrose, 2 mM DTT and/or wherein said protease is capable of cleaving the protease recognition site according to SEQ ID NO: 4 (xlGATE16) with at least 20% activity as compared to the parent protease with the amino acid sequence of SEQ ID NO: 1, if tested using 500 nM of said protease and a native substrate protein shown in SEQ ID NO: 5 (His 14 -xlGATE16-MBP) at standard conditions of 1 hour incubation at 0 °C, 100 μM initial concentration of substrate protein in a buffer consisting of 250 mM NaCl, 40 mM Tris/HCI pH 7.5, 2 mM MgCl 2, 250 mM sucrose, 2 mM DTT.
A method of managing communication between network nodes (300.1,...300.n) in a network, comprising: identifying, using a database management system, DBMS, directory, a local data element from a plurality of data elements stored in a plurality of physical storage units associated with a plurality of network nodes, wherein the local data element is stored in a local physical storage unit associated with a first network node of said plurality of network nodes, and the DBMS directory indexes the plurality of data elements; identifying, using said DBMS directory, a remote data element from said plurality of data elements, wherein the remote data element is stored in a remote physical storage unit associated with a second network node of said plurality of network nodes; instructing the updating of said remote data element according to remote function execution instructions, wherein the remote function execution instructions cause a remote network function to be executed by said second network node; and instructing the updating of said local data element according to local network function execution instructions, wherein the local network function execution instructions cause a local network function to be executed by a component of said first network node. identifying, using a database management system, DBMS, directory, a local data element from a plurality of data elements stored in a plurality of physical storage units associated with a plurality of network nodes, wherein the local data element is stored in a local physical storage unit associated with a first network node of said plurality of network nodes, and the DBMS directory indexes the plurality of data elements; identifying, using said DBMS directory, a remote data element from said plurality of data elements, wherein the remote data element is stored in a remote physical storage unit associated with a second network node of said plurality of network nodes; instructing the updating of said remote data element according to remote function execution instructions, wherein the remote function execution instructions cause a remote network function to be executed by said second network node; and instructing the updating of said local data element according to local network function execution instructions, wherein the local network function execution instructions cause a local network function to be executed by a component of said first network node.