mhurhangee/ep-ind-claims huggingface dataset:
A method of determining a total amount of a coating polymer in a dosage form, the method comprising: preparing a sample by separating the coating polymer from one or more other constituents of the dosage form, the one or more other constituents of the dosage form having a molecular weight range that overlaps with a molecular weight range of the coating polymer, wherein separating comprises mixing the dosage form with a diluent, preferably being dimethylformamide, characterized in that the method further comprises to selectively dissolve the coating polymer in the diluent, wherein, preferably, the diluent is capable of dissolving the coating polymer but not the one or more other constituents of the dosage form, and analyzing the sample, wherein analyzing the sample comprises quantifying the total amount of the coating polymer in the dosage form. preparing a sample by separating the coating polymer from one or more other constituents of the dosage form, the one or more other constituents of the dosage form having a molecular weight range that overlaps with a molecular weight range of the coating polymer, wherein separating comprises mixing the dosage form with a diluent, preferably being dimethylformamide, characterized in that the method further comprises to selectively dissolve the coating polymer in the diluent, wherein, preferably, the diluent is capable of dissolving the coating polymer but not the one or more other constituents of the dosage form, and analyzing the sample, wherein analyzing the sample comprises quantifying the total amount of the coating polymer in the dosage form.
A cytophilic peptide-bound high-density lipoprotein, comprising a high-density lipoprotein and a cytophilic peptide for use in a diagnosis, prevention or treatment of a disease of the posterior eye segment, wherein the cytophilic peptide is at least one kind selected from the group consisting of penetratin, polyarginine, transportan, Pep-1 and MTS.
A system for sealing an annular space between an inner wall of a tubular opening and one tube, cable or duct which extends through the tubular opening in the axial direction thereof, wherein the system comprises at least two segmental parts for forming a sealing plug in the annular space, each segmental part is made of an elastic material, each segmental part being provided with a small-diameter-end for facilitating insertion of the plug in the annular space and a large-diameter-end for positioning at the end of the tubular opening from which the segmental parts are inserted into the annular space, each segmental part further having a number of outer ribs spaced apart in a longitudinal direction for realizing, in use, circumferentially extending outer contact surfaces between the sealing plug and the inner wall of the opening, each segmental part further being provided with a number of inner ribs spaced apart in the longitudinal direction for realizing, in use, circumferentially extending inner contact surfaces between the sealing plug and the tube, cable or duct, wherein at least one of the outer ribs and one of the inner ribs meet in uninserted state of the plug the following geometric condition: - the outer rib has in cross-section the shape of a sawtooth having a rising surface rising radially outwardly toward the large-diameter-end of the plug and having a falling surface with an angled inward bend for facilitating relative movement of parts (11, 12) of the falling surface on opposite sides of a pivotal point of the angled bend; - the inner rib has a top surface extending in circumferential direction and in longitudinal direction for forming one of the inner contact surfaces; and - an imaginary straight line extending in a transverse direction both coincides with the pivotal point of the angled bend and intersects the top surface. - the outer rib has in cross-section the shape of a sawtooth having a rising surface rising radially outwardly toward the large-diameter-end of the plug and having a falling surface with an angled inward bend for facilitating relative movement of parts (11, 12) of the falling surface on opposite sides of a pivotal point of the angled bend; - the inner rib has a top surface extending in circumferential direction and in longitudinal direction for forming one of the inner contact surfaces; and - an imaginary straight line extending in a transverse direction both coincides with the pivotal point of the angled bend and intersects the top surface.
A multilayer transparent conductive film, comprising: an Ag film that is formed of Ag or an Ag alloy, the Ag alloy optionally including 0.2 at% to 10.0 at% of one element or two or more elements in total selected from the group consisting of Cu, Sn, Sb, Ti, Mg, Zn, Ge, In, Al, Ga, Pd, Au, Pt, Bi, Mn, Sc, Y, Nd, Sm, Eu, Gd, Tb, and Er and a balance of Ag and inevitable impurities; and a transparent conductive oxide film (11, 13) that is disposed on two opposite surfaces of the Ag film, wherein the transparent conductive oxide film (11, 13) is formed of an oxide including Zn, Ga, Ti, and optionally Y, characterized in that atomic proportions with respect to all the metal elements included in the transparent conductive oxide film (11, 13) are Ga: 1.0 at% to 30.0 at%, Ti: 0.1 at% to 10.0 at%, optionally Y: 0.1 at% to 10.0 at%, and a balance of Zn. an Ag film that is formed of Ag or an Ag alloy, the Ag alloy optionally including 0.2 at% to 10.0 at% of one element or two or more elements in total selected from the group consisting of Cu, Sn, Sb, Ti, Mg, Zn, Ge, In, Al, Ga, Pd, Au, Pt, Bi, Mn, Sc, Y, Nd, Sm, Eu, Gd, Tb, and Er and a balance of Ag and inevitable impurities; and a transparent conductive oxide film (11, 13) that is disposed on two opposite surfaces of the Ag film, wherein the transparent conductive oxide film (11, 13) is formed of an oxide including Zn, Ga, Ti, and optionally Y, characterized in that atomic proportions with respect to all the metal elements included in the transparent conductive oxide film (11, 13) are Ga: 1.0 at% to 30.0 at%, Ti: 0.1 at% to 10.0 at%, optionally Y: 0.1 at% to 10.0 at%, and a balance of Zn.
A container for the transport and / or storage of a lentiform and / or substantially circular biological material, comprising: a first element having a substantially circular cylindrical shaped cavity for containing said material and a circular crown-shaped base coaxial to the cavity, wherein the diameter of the base is greater than the diameter defined by the cylindrical cavity; a second substantially circular shaped element having a horizontal surface and a vertical edge with an inner surface and an outer surface, said second element being couplable to the first element, in such a way that, in a coupling configuration, a closed space is defined between the horizontal surface of the second element and the cavity of the first element, and a sealing means positioned between the first and the second element (10, 20), configured to seal from outside the space defined by the cavity and the horizontal surface, characterized in that the first element and the second element are made of a mirror-polished steel and the cylindrical cavity has an internal diameter comprised between 17.5 mm and 25.5 mm and a depth comprised between 5 mm and 15 mm. a first element having a substantially circular cylindrical shaped cavity for containing said material and a circular crown-shaped base coaxial to the cavity, wherein the diameter of the base is greater than the diameter defined by the cylindrical cavity; a second substantially circular shaped element having a horizontal surface and a vertical edge with an inner surface and an outer surface, said second element being couplable to the first element, in such a way that, in a coupling configuration, a closed space is defined between the horizontal surface of the second element and the cavity of the first element, and a sealing means positioned between the first and the second element (10, 20), configured to seal from outside the space defined by the cavity and the horizontal surface, characterized in that the first element and the second element are made of a mirror-polished steel and the cylindrical cavity has an internal diameter comprised between 17.5 mm and 25.5 mm and a depth comprised between 5 mm and 15 mm.
A negative thermal expansion material comprising spherical zirconium tungsten phosphate having a BET specific surface area of 2 m 2 /g or smaller; wherein a degree of sphericity is 0.90 or more and 1 or less.
An apparatus for separating solid materials, the apparatus comprising: a channel for receiving a liquid and the materials to be separated, the channel being provided with an agitation surface; means for directing streams of fluid at the materials to be separated, the streams of fluid urging the materials over and against the agitation surface to separate the materials; wherein when the apparatus is in use heavier material is urged along the bottom of the channel to an exit under the action of the streams of fluid, and lighter material separated from the heavier material rises to the surface of the liquid; and wherein the agitation surface comprises a plurality of formations each extending across at least a portion of the width of the channel, each formation comprising an ascending surface up which the materials travel as they are urged along the channel, and a descending surface down which the materials travel as they are urged along the channel, characterised in that at least part of the ascending surface having a steeper slope with respect to the base of the channel than the descending surface. a channel for receiving a liquid and the materials to be separated, the channel being provided with an agitation surface; means for directing streams of fluid at the materials to be separated, the streams of fluid urging the materials over and against the agitation surface to separate the materials; wherein when the apparatus is in use heavier material is urged along the bottom of the channel to an exit under the action of the streams of fluid, and lighter material separated from the heavier material rises to the surface of the liquid; and wherein the agitation surface comprises a plurality of formations each extending across at least a portion of the width of the channel, each formation comprising an ascending surface up which the materials travel as they are urged along the channel, and a descending surface down which the materials travel as they are urged along the channel, characterised in that at least part of the ascending surface having a steeper slope with respect to the base of the channel than the descending surface.
A method performed by a User Equipment device, UE, for obtaining a key for direct communication with a device over a Proximity Services, ProSe, interface, wherein the UE is comprised within a first communication network and the device is comprised within a second communication network, the method comprising: establishing a UE shared key with a Bootstrapping Server Function, BSF, using a Generic Bootstrapping Architecture, GBA, procedure, and receiving from the BSF a transaction identifier associated with the UE shared key; discovering the device through a discovery procedure after receipt of the transaction identifier; sending the transaction identifier and a Direct Communication Element identifier of at least one Direct Communication Element, which comprises at least one of a ProSe Function and a ProSe Key Management Server, to the device and requesting the device to obtain the direct communication key; deriving a session shared key from at least the UE shared key and the Direct Communication Element identifier; deriving the direct communication key from at least the session shared key and an identifier of the device; receiving a first confirmation message from the device indicating that the device has obtained the direct communication key (132i, 132iii), wherein the first confirmation message comprises a Message Authentication Code, MAC, generated using the direct communication key; checking the MAC using the direct communication key; and sending a second confirmation message to the device, if the check is successful. establishing a UE shared key with a Bootstrapping Server Function, BSF, using a Generic Bootstrapping Architecture, GBA, procedure, and receiving from the BSF a transaction identifier associated with the UE shared key; discovering the device through a discovery procedure after receipt of the transaction identifier; sending the transaction identifier and a Direct Communication Element identifier of at least one Direct Communication Element, which comprises at least one of a ProSe Function and a ProSe Key Management Server, to the device and requesting the device to obtain the direct communication key; deriving a session shared key from at least the UE shared key and the Direct Communication Element identifier; deriving the direct communication key from at least the session shared key and an identifier of the device; receiving a first confirmation message from the device indicating that the device has obtained the direct communication key (132i, 132iii), wherein the first confirmation message comprises a Message Authentication Code, MAC, generated using the direct communication key; checking the MAC using the direct communication key; and sending a second confirmation message to the device, if the check is successful.
A process for the production of a thin walled metal detail with an undercut, whereas a mold is equipped with a first mold half and a second mold half, characterized in that the first mold half is equipped with a core and moveable core the latter giving shape to said undercut wherein, a) the mold in the closed position is filled with metal melt allowed to set after which, b) the mold is opened by withdrawing the second mold half at which, c) the moveable core is pushed out in unison with at least one ejector pin hereby ejecting the metal detail from the mold whereupon, d) the metal detail is removed from the moveable core, that the at least one ejector pin which is pushed out in unison with the moveable core in procedure step c) is withdrawn before procedure step d) and, that the ejection ( step c)) is initiated at a temperature higher than Δ wherein Δ is 1⁄2 the temperature difference between ambient temperature (23°C) and the setting or solidification temperature of the injected metal. a) the mold in the closed position is filled with metal melt allowed to set after which, b) the mold is opened by withdrawing the second mold half at which, c) the moveable core is pushed out in unison with at least one ejector pin hereby ejecting the metal detail from the mold whereupon, d) the metal detail is removed from the moveable core,
An optical apparatus (100; 200; 300) comprising: an optical resonator (102; 202; 302) defining an optical resonator path (110; 210; 310) for an optical resonator beam (150; 250; 350); and an optical beam expander (104; 204; 304) for receiving and expanding an optical beam output from the optical resonator (102; 202; 302), the optical beam expander (104; 204; 304) defining an optical beam expander path (124; 224; 324) for a divergent optical beam expander beam (152; 252; 352), wherein the optical resonator path (110; 210; 310) and the optical beam expander path (124; 224; 324) are configured such that the optical resonator beam (150; 250; 350) and the divergent optical beam expander beam (152; 252; 352) at least partially intersect. an optical resonator (102; 202; 302) defining an optical resonator path (110; 210; 310) for an optical resonator beam (150; 250; 350); and an optical beam expander (104; 204; 304) for receiving and expanding an optical beam output from the optical resonator (102; 202; 302), the optical beam expander (104; 204; 304) defining an optical beam expander path (124; 224; 324) for a divergent optical beam expander beam (152; 252; 352), wherein the optical resonator path (110; 210; 310) and the optical beam expander path (124; 224; 324) are configured such that the optical resonator beam (150; 250; 350) and the divergent optical beam expander beam (152; 252; 352) at least partially intersect.
A single-component coating composition comprising: an N-substituted urea polymer with extended chains and terminal alkoxysilanes, wherein said polymer is a reaction product of (a) an aliphatic polyisocyanate, (b) an N-substituted amino-functional alkoxysilane, and (c) a secondary diamine chain extender, wherein no unreacted isocycanate remains in said polymer. an N-substituted urea polymer with extended chains and terminal alkoxysilanes, wherein said polymer is a reaction product of (a) an aliphatic polyisocyanate, (b) an N-substituted amino-functional alkoxysilane, and (c) a secondary diamine chain extender, wherein no unreacted isocycanate remains in said polymer.
A method for crack monitoring in a structure of interest using Acoustic Emission sensing, comprising: - placing a plurality of AE detectors on a single device on the structure of interest, having known relative detector positions; - detecting during a preset time window acoustic power emitted by an AE source in selected detectors as time traces; - for every set of waveforms detected at the detector locations, identifying a most plausible wave mode and speed in an optimization routine, by minimizing an error function associated with an assumed combination of the source location, speed of a dominant wave mode, and identified arrival times of a dominant wave mode with a maximum acoustic amplitude at the detector locations, thereby finding a location of a source of acoustic emission on the structure of interest and a dominant wave mode; - identifying, in a frequency interval of interest a next to maximum acoustic amplitude as a non-dominant wave mode in the time window; - correlating a ratio of dominant and non-dominant wave mode amplitudes to a crack depth using a characteristic curve that relates crack depth to an amplitude and ratio of wave mode compositions; and - populating in a history bank crack depths measured for corresponding locations, so that for a selected crack, identified by a calculated location of the AE source, its depth be resolved by matching a calculated ratio of wave mode amplitudes on the characteristic curve - wherein the wave modes are expressed as zero order symmetric Lamb waves S0 and antisymmetric Lamb waves A0. - placing a plurality of AE detectors on a single device on the structure of interest, having known relative detector positions; - detecting during a preset time window acoustic power emitted by an AE source in selected detectors as time traces; - for every set of waveforms detected at the detector locations, identifying a most plausible wave mode and speed in an optimization routine, by minimizing an error function associated with an assumed combination of the source location, speed of a dominant wave mode, and identified arrival times of a dominant wave mode with a maximum acoustic amplitude at the detector locations, thereby finding a location of a source of acoustic emission on the structure of interest and a dominant wave mode; - identifying, in a frequency interval of interest a next to maximum acoustic amplitude as a non-dominant wave mode in the time window; - correlating a ratio of dominant and non-dominant wave mode amplitudes to a crack depth using a characteristic curve that relates crack depth to an amplitude and ratio of wave mode compositions; and - populating in a history bank crack depths measured for corresponding locations, so that for a selected crack, identified by a calculated location of the AE source, its depth be resolved by matching a calculated ratio of wave mode amplitudes on the characteristic curve - wherein the wave modes are expressed as zero order symmetric Lamb waves S0 and antisymmetric Lamb waves A0.
A composition comprising: a polymerase comprising 3'-5' exonuclease activity, at least one target nucleic acid molecule which is a genomic DNA, and an amplicon library, wherein the amplicon library comprises at least 100 polynucleotides obtained from amplification of the at least one target nucleic acid molecule, wherein at least some of the polynucleotides comprise a terminator nucleotide, wherein the terminator nucleotide is an irreversible terminator and selected from nucleotides with modification to the alpha group, C3 spacer nucleotides, locked nucleic acids, inverted nucleic acids, 2' fluoro nucleotides, 3' phosphorylated nucleotides, 2'-O-Methyl modified nucleotides, and trans nucleic acids, and wherein at least 5% of the polynucleotides are direct copies of the at least one target nucleic acid molecule. a polymerase comprising 3'-5' exonuclease activity, at least one target nucleic acid molecule which is a genomic DNA, and an amplicon library, wherein the amplicon library comprises at least 100 polynucleotides obtained from amplification of the at least one target nucleic acid molecule, wherein at least some of the polynucleotides comprise a terminator nucleotide, wherein the terminator nucleotide is an irreversible terminator and selected from nucleotides with modification to the alpha group, C3 spacer nucleotides, locked nucleic acids, inverted nucleic acids, 2' fluoro nucleotides, 3' phosphorylated nucleotides, 2'-O-Methyl modified nucleotides, and trans nucleic acids, and wherein at least 5% of the polynucleotides are direct copies of the at least one target nucleic acid molecule. wherein the amplicon library comprises at least 100 polynucleotides obtained from amplification of the at least one target nucleic acid molecule, wherein at least some of the polynucleotides comprise a terminator nucleotide, wherein the terminator nucleotide is an irreversible terminator and selected from nucleotides with modification to the alpha group, C3 spacer nucleotides, locked nucleic acids, inverted nucleic acids, 2' fluoro nucleotides, 3' phosphorylated nucleotides, 2'-O-Methyl modified nucleotides, and trans nucleic acids, and wherein at least 5% of the polynucleotides are direct copies of the at least one target nucleic acid molecule.