An antibody comprising at least one binding site that specifically binds to a LukGH heterodimer, which antibody comprises at least an antibody heavy chain variable region, and an antibody light chain variable region, having the heavy chain and light chain sequences of an antibody, which is selected from the group consisting of a) an antibody comprising a. the HC amino acid sequence of SEQ ID 161; and b. the LC amino acid sequence of SEQ ID 162; b) an antibody comprising a. the HC amino acid sequence of SEQ ID 147; and b. the LC amino acid sequence of SEQ ID 148; c) an antibody comprising a. the HC amino acid sequence of SEQ ID 149; and b. the LC amino acid sequence of SEQ ID 150; d) an antibody comprising a. the HC amino acid sequence of SEQ ID 151; and b. the LC amino acid sequence of SEQ ID 152; e) an antibody comprising a. the HC amino acid sequence of SEQ ID 153; and b. the LC amino acid sequence of SEQ ID 154; f) an antibody comprising a. the HC amino acid sequence of SEQ ID 155; and b. the LC amino acid sequence of SEQ ID 156; g) an antibody comprising a. the HC amino acid sequence of SEQ ID 157; and b. the LC amino acid sequence of SEQ ID 158; h) an antibody comprising a. the HC amino acid sequence of SEQ ID 159; and b. the LC amino acid sequence of SEQ ID 160; i) an antibody comprising a. the HC amino acid sequence of SEQ ID 163; and b. the LC amino acid sequence of SEQ ID 164; j) an antibody comprising a. the HC amino acid sequence of SEQ ID 165; and b. the LC amino acid sequence of SEQ ID 166; k) an antibody comprising a. the HC amino acid sequence of SEQ ID 167; and b. the LC amino acid sequence of SEQ ID 168; l) an antibody comprising a. the HC amino acid sequence of SEQ ID 169; and b. the LC amino acid sequence of SEQ ID 170; and m) an antibody comprising a. the HC amino acid sequence of SEQ ID 171; and b. the LC amino acid sequence of SEQ ID 172. a) an antibody comprising a. the HC amino acid sequence of SEQ ID 161; and b. the LC amino acid sequence of SEQ ID 162; a. the HC amino acid sequence of SEQ ID 161; and b. the LC amino acid sequence of SEQ ID 162; b) an antibody comprising a. the HC amino acid sequence of SEQ ID 147; and b. the LC amino acid sequence of SEQ ID 148; a. the HC amino acid sequence of SEQ ID 147; and b. the LC amino acid sequence of SEQ ID 148; c) an antibody comprising a. the HC amino acid sequence of SEQ ID 149; and b. the LC amino acid sequence of SEQ ID 150; a. the HC amino acid sequence of SEQ ID 149; and b. the LC amino acid sequence of SEQ ID 150; d) an antibody comprising a. the HC amino acid sequence of SEQ ID 151; and b. the LC amino acid sequence of SEQ ID 152; a. the HC amino acid sequence of SEQ ID 151; and b. the LC amino acid sequence of SEQ ID 152; e) an antibody comprising a. the HC amino acid sequence of SEQ ID 153; and b. the LC amino acid sequence of SEQ ID 154; a. the HC amino acid sequence of SEQ ID 153; and b. the LC amino acid sequence of SEQ ID 154; f) an antibody comprising a. the HC amino acid sequence of SEQ ID 155; and b. the LC amino acid sequence of SEQ ID 156; a. the HC amino acid sequence of SEQ ID 155; and b. the LC amino acid sequence of SEQ ID 156; g) an antibody comprising a. the HC amino acid sequence of SEQ ID 157; and b. the LC amino acid sequence of SEQ ID 158; a. the HC amino acid sequence of SEQ ID 157; and b. the LC amino acid sequence of SEQ ID 158; h) an antibody comprising a. the HC amino acid sequence of SEQ ID 159; and b. the LC amino acid sequence of SEQ ID 160; a. the HC amino acid sequence of SEQ ID 159; and b. the LC amino acid sequence of SEQ ID 160; i) an antibody comprising a. the HC amino acid sequence of SEQ ID 163; and b. the LC amino acid sequence of SEQ ID 164; a. the HC amino acid sequence of SEQ ID 163; and b. the LC amino acid sequence of SEQ ID 164; j) an antibody comprising a. the HC amino acid sequence of SEQ ID 165; and b. the LC amino acid sequence of SEQ ID 166; a. the HC amino acid sequence of SEQ ID 165; and b. the LC amino acid sequence of SEQ ID 166; k) an antibody comprising a. the HC amino acid sequence of SEQ ID 167; and b. the LC amino acid sequence of SEQ ID 168; a. the HC amino acid sequence of SEQ ID 167; and b. the LC amino acid sequence of SEQ ID 168; l) an antibody comprising a. the HC amino acid sequence of SEQ ID 169; and b. the LC amino acid sequence of SEQ ID 170; and a. the HC amino acid sequence of SEQ ID 169; and b. the LC amino acid sequence of SEQ ID 170; m) an antibody comprising a. the HC amino acid sequence of SEQ ID 171; and b. the LC amino acid sequence of SEQ ID 172. a. the HC amino acid sequence of SEQ ID 171; and b. the LC amino acid sequence of SEQ ID 172.