mhurhangee/ep-ind-claims huggingface dataset:
A topical formulation for use in impeding lactic acidosis in an individual subjected to tasks which require physical exertion, said topical formulation being for transdermal delivery of an active agent through the skin of a subject, wherein said active agent comprises sodium bicarbonate, wherein said formulation comprises lecithin organogel at 25% - 70% w/w of said formulation, said lecithin organogel comprising isopropyl palmitate, sodium bicarbonate at 0.01% - 50% w/w of the formulation, benzyl alcohol at 0.5%-20% w/w of the formulation, a poloxamer at 2% -25% w/w of the formulation, and water at least in an amount in molar excess of the poloxamer. lecithin organogel at 25% - 70% w/w of said formulation, said lecithin organogel comprising isopropyl palmitate, sodium bicarbonate at 0.01% - 50% w/w of the formulation, benzyl alcohol at 0.5%-20% w/w of the formulation, a poloxamer at 2% -25% w/w of the formulation, and water at least in an amount in molar excess of the poloxamer.
An electrode drying device, comprising: a drying chamber configured to accommodate a roll-shaped electrode; and a drying unit provided in the drying chamber to dry the electrode, the drying unit being configured to surround the electrode, the drying unit including: a heat source; and a clamping part for supplying the heat provided from the heat source to the electrode, the clamping part being configured to surround an outer surface of the electrode, an inner surface (212, 222) of the clamping part being in direct contact with the outer surface (12, 14) of the electrode. a drying chamber configured to accommodate a roll-shaped electrode; and a drying unit provided in the drying chamber to dry the electrode, the drying unit being configured to surround the electrode, a heat source; and a clamping part for supplying the heat provided from the heat source to the electrode, the clamping part being configured to surround an outer surface of the electrode, an inner surface (212, 222) of the clamping part being in direct contact with the outer surface (12, 14) of the electrode.
A composition for topical or systemic administration to a mammal comprising a pharmaceutically or cosmetically acceptable carrier and a therapeutically effective amount of a peptide derivative having the following generic Formula: R 1 -AAB- n -AAC-R 2 Formula wherein R 1 is an acyl radical selected from the group consisting of Ac, Pr and Bz; R 2 is selected from the group consisting of OH, OEt, NH 2, NHOH and NHNH 2; AAB is an amino-terminal amino acid residue; n is a peptide having n amino acid residues; n is 1; AAC is a carboxyl-terminal amino acid residue; and AAB, AAA, AAC are L-Tyr, L-Tyr, L-Tyr, respectively.
A method for producing multilayer abrasive particles, comprising the following method steps: providing a substrate support and at least one dispersion of an abrasive particle precursor; repeatedly positioning at least one grid structure above the substrate support, covering areas being defined by at least partially covered grid meshes and printing areas being defined by open grid meshes; applying the at least one dispersion onto the grid structure, a contact being formed between the grid structure and the substrate support or layers arranged on the substrate support, and a dispersion layer being deposited in the printing areas on the substrate support or on the layers previously arranged thereon when the contact is lifted, and subsequently drying each deposited dispersion layer to form a layer, wherein closed hollow bodies each having a shell made of layers and a hollow space enclosed by the shell are produced, characterized in that a grid structure whose covering areas are each completely surrounded by a printing area is used in at least one depositing process, and grid structures whose printing areas are each completely surrounded by a covering area are used in a first and in a last depositing process. providing a substrate support and at least one dispersion of an abrasive particle precursor; repeatedly positioning at least one grid structure above the substrate support, covering areas being defined by at least partially covered grid meshes and printing areas being defined by open grid meshes; applying the at least one dispersion onto the grid structure, a contact being formed between the grid structure and the substrate support or layers arranged on the substrate support, and a dispersion layer being deposited in the printing areas on the substrate support or on the layers previously arranged thereon when the contact is lifted, and subsequently drying each deposited dispersion layer to form a layer, wherein closed hollow bodies each having a shell made of layers and a hollow space enclosed by the shell are produced, characterized in that a grid structure whose covering areas are each completely surrounded by a printing area is used in at least one depositing process, and grid structures whose printing areas are each completely surrounded by a covering area are used in a first and in a last depositing process.
A sliding device for doors, provided with multiple adjustments, consisting of a carriage or slider provided with rollers or bearings and of a profile section with a substantially "L"-shaped section, constrained, when mounted, to the front side of the door facing the wall on which a passage area is created, abutted, when mounted, to a lowered portion formed at the upper edge of the same door and provided with an embossed and shaped portion having a shape complementary to the profile section of the rollers along which it slides, characterized in that the carriage or slider comprises a first body or front body, having a substantially rectangular plan, and a second body or rear body designed to be connected to the first front body and provided with opposed substantially cylindrical appendages (16, 18) with a vertical passing-through hole in which respective cylindrical bodies are inserted, along which an offset and passing-through threaded hole is bored, to form as many eccentrics, in each of said holes being inserted a threaded stem or screw that protrudes from the upper side of the front body on which corresponding slots are made.
A bearing housing of the type incorporating a substantially sleeve-formed main body (3; 12), with an internal bearing seat for accommodating a bearing, and having at one axial side a radial flange (9; 14) projecting outside the outer wall surface of the main body, and having adjacent its outer edge a number of through-holes (10, 10a; 15, 15a) for attachment bolts for fitting the bearing housing to a substantially planar, vertical surface, characterized therein, that the through-holes (10a, 15a) situated at the side of the flange (9; 14), opposite the side towards which a load acts on the bearing housing, have a bigger cross-section than the through-holes (10, 15) arranged at the flange side towards which the load acts, in order to initially direct reaction forces acting on the flange of the bearing housing following the load on the bearing housing to the smaller bore/bores only.
A vehicle-side connector configured such that a charging connector connected to a charger is connectable thereto from front and to be connected to a battery mounted in a vehicle, comprising: a lock fitting portion open forward and configured such that a tip part of a lock arm provided in the charging connector is fitted thereinto from front; and a locked portion provided in the lock fitting portion and formed by mounting a lock plate, to which the tip part of the lock arm is to be locked, on a base portion, wherein the lock plate is made of metal, characterized in that a mounting hole for mounting the lock plate from behind is formed on a back wall of the lock fitting portion and a cover is provided to close the mounting hole. a lock fitting portion open forward and configured such that a tip part of a lock arm provided in the charging connector is fitted thereinto from front; and a locked portion provided in the lock fitting portion and formed by mounting a lock plate, to which the tip part of the lock arm is to be locked, on a base portion, wherein the lock plate is made of metal, characterized in that a mounting hole for mounting the lock plate from behind is formed on a back wall of the lock fitting portion and a cover is provided to close the mounting hole.
An illumination device for use in an ophthalmic surgical apparatus, the illumination device comprising: a fiber optic having a proximal end; and a connector coupled to the fiber optic comprising a datum surface disposed a predetermined distance from the proximal end, the connector configured and arranged to connect with the surgical apparatus such that the datum surface positions the proximal end at a predetermined location within the surgical apparatus when the connector is connected to the surgical apparatus; characterized in that: the illumination device is adapted to fit into and move a collar within a port in the surgical apparatus upon insertion of the connector into the port, thereby opening a shutter within the surgical apparatus to transmit light through the fiber optic. a fiber optic having a proximal end; and a connector coupled to the fiber optic comprising a datum surface disposed a predetermined distance from the proximal end, the connector configured and arranged to connect with the surgical apparatus such that the datum surface positions the proximal end at a predetermined location within the surgical apparatus when the connector is connected to the surgical apparatus;
An aluminum alloy wire having a composition comprising Mg: 0.1 mass% to 1.0 mass%, Si: 0.1 mass% to 1.2 mass%, Fe: 0.10 mass% to 1.40 mass%, Ti: 0.001 mass% to 0.100 mass%, B: 0.001 mass% to 0.030 mass%, Cu: 0 mass% to 1.00 mass%, Ag: 0 mass% to 0.50 mass%, Au: 0 mass% to 0.50 mass%, Mn: 0 mass% to 1.00 mass%, Cr: 0 mass% to 1.00 mass%, Zr: 0 mass% to 0.50 mass%, Hf: 0 mass% to 0.50 mass%, V: 0 mass% to 0.50 mass%, Sc: 0 mass% to 0.50 mass%, Co: 0 mass% to 0.50 mass%, Ni: 0 mass% to 0.50 mass%, and the balance: Al and inevitable impurities, wherein a number of compound particles present on a surface and having a diameter of greater than or equal to 1 μm in terms of equivalent circle diameter is less than or equal to one per 100 μm 2, and a tensile strength is greater than or equal to 200 MPa as measured in conformity with JIS Z 2241:2011, the compound particles are Fe-based compound particles, a thickness of a surface oxide layer is less than or equal to 500 nm, the aluminum alloy wire has a plated film on a surface thereof, and a presence ratio of pinholes measured on the surface after plating, said pinholes each having a diameter of greater than or equal to 1 μm in terms of equivalent circle diameter is less than or equal to one pinhole/mm 2, wherein the number of compound particles present on surface and having a diameter of greater than or equal to 1 μm in terms of equivalent circle diameter, the thickness of a surface oxide layer and a presence of pinholes each having a diameter of greater than or equal to 1 μm in terms of equivalent circle diameter are determined by the methods disclosed in the description. wherein a number of compound particles present on a surface and having a diameter of greater than or equal to 1 μm in terms of equivalent circle diameter is less than or equal to one per 100 μm 2, and a tensile strength is greater than or equal to 200 MPa as measured in conformity with JIS Z 2241:2011, the compound particles are Fe-based compound particles, a thickness of a surface oxide layer is less than or equal to 500 nm, the aluminum alloy wire has a plated film on a surface thereof, and a presence ratio of pinholes measured on the surface after plating, said pinholes each having a diameter of greater than or equal to 1 μm in terms of equivalent circle diameter is less than or equal to one pinhole/mm 2, wherein the number of compound particles present on surface and having a diameter of greater than or equal to 1 μm in terms of equivalent circle diameter, the thickness of a surface oxide layer and a presence of pinholes each having a diameter of greater than or equal to 1 μm in terms of equivalent circle diameter are determined by the methods disclosed in the description.
Method of manufacturing a cocoa-flavored frozen dessert, comprising the steps of: a) adding water to cocoa beans or nibs to form a suspension; b) wet grinding said suspension; c) subjecting said suspension to a heat treatment at a temperature of 70°C or less; d) separating the suspension into a water phase (heavy phase), a fat phase (light phase) and a solid phase, said fat phase comprising cocoa butter as a major component and solids and/or water as minor components and said solid phase comprising cocoa powder and water; and e) subjecting a mixture comprising a natural or artificial sweetener to pasteurization, homogenisation and freezing to obtain the cocoa-flavored frozen dessert; wherein the non-dried solid phase obtained in step d) and having a water content of 50 % by weight or more based on the total weight of the solid phase is added to the mixture before or during step e), and wherein the cocoa-flavored frozen dessert obtained in step e) comprises at least 2 wt.-% of cocoa powder as introduced by the non-dried solid phase, based on the total solid content of the cocoa-flavored frozen dessert. a) adding water to cocoa beans or nibs to form a suspension; b) wet grinding said suspension; c) subjecting said suspension to a heat treatment at a temperature of 70°C or less; d) separating the suspension into a water phase (heavy phase), a fat phase (light phase) and a solid phase, said fat phase comprising cocoa butter as a major component and solids and/or water as minor components and said solid phase comprising cocoa powder and water; and e) subjecting a mixture comprising a natural or artificial sweetener to pasteurization, homogenisation and freezing to obtain the cocoa-flavored frozen dessert; wherein the non-dried solid phase obtained in step d) and having a water content of 50 % by weight or more based on the total weight of the solid phase is added to the mixture before or during step e), and wherein the cocoa-flavored frozen dessert obtained in step e) comprises at least 2 wt.-% of cocoa powder as introduced by the non-dried solid phase, based on the total solid content of the cocoa-flavored frozen dessert. wherein the non-dried solid phase obtained in step d) and having a water content of 50 % by weight or more based on the total weight of the solid phase is added to the mixture before or during step e), and wherein the cocoa-flavored frozen dessert obtained in step e) comprises at least 2 wt.-% of cocoa powder as introduced by the non-dried solid phase, based on the total solid content of the cocoa-flavored frozen dessert.
A solar module having at least two substring groups (A,B,C), each substring group (A,B,C) comprising - an upper substring (A1,B1,C1) having a number of solar cells that are connected in series, wherein the solar cells of the upper substring (A1,B1,C1) are arranged in a matrix form comprising at least two adjacent columns and multiple rows, - a lower substring (A2,B2,C2) having a number of solar cells, that are connected in series, wherein the solar cells are arranged in a matrix form comprising at least two adjacent columns and multiple rows and wherein the lower substring (A2,B2,C2) and the upper substring (A1,B1,C1) have the same number of solar cells (11,21) and - a transverse connector electrically connects the lower substring (A2,B2,C2) and the upper substring (A1,B1,C1) in parallel to form the substring group (A,B,C) and - a bypass diode that is electrically arranged in the transverse connector, wherein the transverse connector of each substring group (A,B,C) are in contact with one another in such a manner that the substring groups (A,B,C) are electrically connected to one another in series, wherein the solar cells (11, 21) are designed as full cells, characterized in that two columns of the lower substring (A2,B2,C2) have a different number of solar cells and that two columns of the associated upper substring (A1,B1,C1) in the substring group (A,B,C) have a different number of solar cells with the result that the number of solar cells of the upper substring (A1,B1,C1) and the number of solar cells in the lower substring (A2,B2,C2) is uneven. - an upper substring (A1,B1,C1) having a number of solar cells that are connected in series, wherein the solar cells of the upper substring (A1,B1,C1) are arranged in a matrix form comprising at least two adjacent columns and multiple rows, - a lower substring (A2,B2,C2) having a number of solar cells, that are connected in series, wherein the solar cells are arranged in a matrix form comprising at least two adjacent columns and multiple rows and wherein the lower substring (A2,B2,C2) and the upper substring (A1,B1,C1) have the same number of solar cells (11,21) and - a transverse connector electrically connects the lower substring (A2,B2,C2) and the upper substring (A1,B1,C1) in parallel to form the substring group (A,B,C) and - a bypass diode that is electrically arranged in the transverse connector, wherein the transverse connector of each substring group (A,B,C) are in contact with one another in such a manner that the substring groups (A,B,C) are electrically connected to one another in series, wherein the solar cells (11, 21) are designed as full cells, characterized in that two columns of the lower substring (A2,B2,C2) have a different number of solar cells and that two columns of the associated upper substring (A1,B1,C1) in the substring group (A,B,C) have a different number of solar cells with the result that the number of solar cells of the upper substring (A1,B1,C1) and the number of solar cells in the lower substring (A2,B2,C2) is uneven.
An agricultural harvester comprising at least one drive axle equipped with tyres and at least one further axle which is equipped with tyres and which can be used by means of an all-wheel drive which can be cut in and out as a towed axle or driven axle, and a tyre pressure regulating installation including means (11, 12, 21) for altering the internal tyre pressure as well as a control unit, characterised in that at least the further axle is equipped with tyres whose internal tyre pressure assumes a higher value when the all-wheel drive is cut in than when the all-wheel drive is cut out, by the control unit detecting cutting in or cutting out of the all-wheel drive and initiating a change in the internal tyre pressure of the tyres by the tyre pressure regulating installation.
Plant phenols for use in the prevention or treatment of eosinophilic esophagitis, wherein the phenols are selected from the group consisting of rosemarinic acid, ellagic acid, cholorgenic acid, or mixtures thereof.
An actuating system for an actuatable door, the actuating system comprising: a rotatable latching shaft; a rotatable locking shaft; a latching device comprising: a latch that is non-rotatably mounted to the rotatable latching shaft and adapted for maintaining the actuatable door in a closed position, wherein rotation of the rotatable latching shaft causes a rotation of the latch, and a latch securing lever that comprises first and second contact surfaces (7a, 7h), wherein the first contact surface is adapted to engage with the latch to maintain the latch in a closed and secured position; and a locking device comprising: a locking cam that is non-rotatably mounted to the rotatable locking shaft such that a rotation of the rotatable locking shaft causes a rotation of the locking cam, wherein the locking cam drives the latch securing lever and comprises third and fourth contact surfaces (6a, 6d), wherein the third contact surface is adapted to engage with the latch to lock the latch in a closed and latched position, and wherein the fourth contact surface is adapted to engage with the second contact surface of the latch securing lever to prevent the latch securing lever from disengaging from a latched position while the locking cam is engaged. a rotatable latching shaft; a rotatable locking shaft; a latching device comprising: a latch that is non-rotatably mounted to the rotatable latching shaft and adapted for maintaining the actuatable door in a closed position, wherein rotation of the rotatable latching shaft causes a rotation of the latch, and a latch securing lever that comprises first and second contact surfaces (7a, 7h), wherein the first contact surface is adapted to engage with the latch to maintain the latch in a closed and secured position; and a latch that is non-rotatably mounted to the rotatable latching shaft and adapted for maintaining the actuatable door in a closed position, wherein rotation of the rotatable latching shaft causes a rotation of the latch, and a latch securing lever that comprises first and second contact surfaces (7a, 7h), wherein the first contact surface is adapted to engage with the latch to maintain the latch in a closed and secured position; and a locking device comprising: a locking cam that is non-rotatably mounted to the rotatable locking shaft such that a rotation of the rotatable locking shaft causes a rotation of the locking cam, wherein the locking cam drives the latch securing lever and comprises third and fourth contact surfaces (6a, 6d), wherein the third contact surface is adapted to engage with the latch to lock the latch in a closed and latched position, and wherein the fourth contact surface is adapted to engage with the second contact surface of the latch securing lever to prevent the latch securing lever from disengaging from a latched position while the locking cam is engaged.
A sustained release composition for intravitreal administration comprising a plurality of microparticles suspended in a carrier, wherein the carrier comprises a surfactant, wherein said microparticles release a biologically active agent comprising an anti-VEGF aptamer over a period of at least 1 month; said microparticles have a mean diameter of less than 45 μm; said microparticles comprise a polymeric material incorporating a core load of at least 7 wt % of said anti-VEGF aptamer; said microparticles release said anti-VEGF aptamer at an initial burst of less than 15 wt % of said core load within 24 hours of administration; and said microparticles are syringable through a 27-gauge needle or narrower when suspended in the carrier suitable for intravitreal administration.
Device for the adjustment of the pitch of a rotor blade of a wind turbine comprising - a pitch actuator in form of a hydraulic pitch cylinder or an electric pitch actuator acting on an adjusting plane (P, 41) for the adjustment of the pitch and - a fixing device to which the pitch actuator is attached, and which is provided for an attachment to a hub of a wind turbine, the fixing device comprises a first and a second bearing shaft (A, B) allowing a pendulum motion of the pitch actuator relatively to the fixing device wherein both the first and the second bearing shaft (A, B) are arranged respectively under a certain tilt angle (α) relatively to the adjusting plane (P, 41) which tilt angle (α) is respectively substantially different from 0° or 90°. - a pitch actuator in form of a hydraulic pitch cylinder or an electric pitch actuator acting on an adjusting plane (P, 41) for the adjustment of the pitch and - a fixing device to which the pitch actuator is attached, and which is provided for an attachment to a hub of a wind turbine,