An automated test method for risk and integrity testing of radiopharmaceutical filtration membrane comprising: risk testing by gas, comprising following steps: Step S11: passing nitrogen or an inert gas of 0.35 bar (5 psi) gauge pressure through a membrane disposed in a dried state; Step S12: conveying nitrogen or inert gas into bubbles bottles through a solenoid valve to observe conditions of bubble generation. risk testing by liquid, comprising at least the following steps: Step S21: passing radiopharmaceutical product through a membrane for filtration with nitrogen or an inert gas of 1.38 to 1.72 bar (20 to 25 psi) gauge pressure; Step S22: collecting the radiopharmaceutical product in a radiopharmaceutical vial after the filtration; Step S23: passing gas through the membrane in moist state and checking the gas gauge pressure if it is maintained at the same as in step S21or plunged in a range of 0.35-0.83 bar (5 ∼ 12 psi) to determine if holes exist in the membrane. integrity test by gas, comprising at least the following steps: Step S31: passing nitrogen or an inert gas of 1.38 to 1.72 bar (20 to 25 psi) gauge pressure through a membrane; Step S32: checking the gauge pressure if it is maintained at the same as in step S31or plunged in a range of 0.35 ∼0.83 bar (5 ∼ 12 psi) to determine the integrity of the membrane after production. risk testing by gas, comprising following steps: Step S11: passing nitrogen or an inert gas of 0.35 bar (5 psi) gauge pressure through a membrane disposed in a dried state; Step S12: conveying nitrogen or inert gas into bubbles bottles through a solenoid valve to observe conditions of bubble generation. Step S11: passing nitrogen or an inert gas of 0.35 bar (5 psi) gauge pressure through a membrane disposed in a dried state; Step S12: conveying nitrogen or inert gas into bubbles bottles through a solenoid valve to observe conditions of bubble generation. risk testing by liquid, comprising at least the following steps: Step S21: passing radiopharmaceutical product through a membrane for filtration with nitrogen or an inert gas of 1.38 to 1.72 bar (20 to 25 psi) gauge pressure; Step S22: collecting the radiopharmaceutical product in a radiopharmaceutical vial after the filtration; Step S23: passing gas through the membrane in moist state and checking the gas gauge pressure if it is maintained at the same as in step S21or plunged in a range of 0.35-0.83 bar (5 ∼ 12 psi) to determine if holes exist in the membrane. Step S21: passing radiopharmaceutical product through a membrane for filtration with nitrogen or an inert gas of 1.38 to 1.72 bar (20 to 25 psi) gauge pressure; Step S22: collecting the radiopharmaceutical product in a radiopharmaceutical vial after the filtration; Step S23: passing gas through the membrane in moist state and checking the gas gauge pressure if it is maintained at the same as in step S21or plunged in a range of 0.35-0.83 bar (5 ∼ 12 psi) to determine if holes exist in the membrane. integrity test by gas, comprising at least the following steps: Step S31: passing nitrogen or an inert gas of 1.38 to 1.72 bar (20 to 25 psi) gauge pressure through a membrane; Step S32: checking the gauge pressure if it is maintained at the same as in step S31or plunged in a range of 0.35 ∼0.83 bar (5 ∼ 12 psi) to determine the integrity of the membrane after production. Step S31: passing nitrogen or an inert gas of 1.38 to 1.72 bar (20 to 25 psi) gauge pressure through a membrane; Step S32: checking the gauge pressure if it is maintained at the same as in step S31or plunged in a range of 0.35 ∼0.83 bar (5 ∼ 12 psi) to determine the integrity of the membrane after production.