mhurhangee/ep-ind-claims huggingface dataset:
An actuator cap (1; 50) for a fluid spray dispenser comprising an first body part adapted for connection to a container for a fluid to be dispensed and incorporating a spray channel arrangement; and an second body part incorporating an actuator button, the second body part being rotatable with respect to the first body part from a first position in which the actuator button is non-elevated into a second position in which the actuator button is elevated and capable of depression to cause depression of a part of the spray channel arrangement; characterised in that the actuator button defines a first cam profile along which a first cam follower defined by the first body part travels to cause elevation or retraction of the actuator button when the second body part is rotated; and the actuator button defines a second cam profile that bears against said part of the spray channel arrangement such that when the actuator button is in its elevated position and depressed the actuator button depresses said second cam profile and in turn depresses said part of the spray channel arrangement relative to the first body part to dispense the fluid from the container when in use. an first body part adapted for connection to a container for a fluid to be dispensed and incorporating a spray channel arrangement; and an second body part incorporating an actuator button, the second body part being rotatable with respect to the first body part from a first position in which the actuator button is non-elevated into a second position in which the actuator button is elevated and capable of depression to cause depression of a part of the spray channel arrangement; the actuator button defines a first cam profile along which a first cam follower defined by the first body part travels to cause elevation or retraction of the actuator button when the second body part is rotated; and the actuator button defines a second cam profile that bears against said part of the spray channel arrangement such that when the actuator button is in its elevated position and depressed the actuator button depresses said second cam profile and in turn depresses said part of the spray channel arrangement relative to the first body part to dispense the fluid from the container when in use.
A preparation method of a 2-substituted-2H-1,2,3-triazole derivative having the following structure: wherein the method comprises the following steps: dissolving the compound shown in the following formula III in a mass to volume ratio of 1:2∼20 of diethyl ether, tetrahydrofuran or 1,4-dioxane or methyltetrahydrofuran, cooling to -78∼0°C, adding isopropylmagnesium chloride or isopropylmagnesium chloride-lithium chloride composite, stirring for 0.5∼2 hours, inleting chlorine or adding N-chlorosuccinimide, or 1,3-dichloro-5,5-dimethylhydantoin, or adding iodine, stirring for 5∼30 minutes, heating up to room temperature, extracting by using organic solvent after quenching by using saturated ammonium chloride aqueous solution, drying via anhydrous sodium sulfate or anhydrous magnesium sulfate, concentrating to dry under reduced pressure, recrystallizing the obtained concentrate to obtain the 2-substituted-2H-1,2,3-triazole derivative; wherein R represents alkyl, aryl, aralkyl, cycloalkyl, cycloalkyl alkyl, heteroaryl, heteroaryl alkyl, or heterocyclic alkyl, and X represents chlorine or iodine.
Friction lining, notably for a dry clutch, in particular for a motor vehicle, comprising, by weight, 10 to 20%, preferably 12 to 15%, of glass fibres, more than 90%, by weight, of the glass fibres being grouped in the form of strands of glass fibres with a length of greater than 2.5 mm, preferably greater than 2.8 mm, and less than 4 mm, preferably less than 3.6 mm, more than 30% by number of the strands of glass fibres having a width of greater than 0.5 mm.
A compounds of formula or a pharmaceutically acceptable salt thereof, wherein the dotted line is an optional double bond; A and B are each independently an aryl or heteroaryl; R1 is, an alkyl or cycloalkyl; R2 is absent when the dotted line is a double bond or R2 is hydrogen, an alkyl or cycloalkyl when the dotted line is absent; W is OH when the dotted line is absent or W is O when the dotted line is a double bond; X is O, CH 2, CHR7 or CR7R7, where R7 is in an alkyl or fluoroalkyl; Y is NR10, NR10, O, CH 2, CHR7 or CR7R7, where R7 is in an alkyl or fluoroalkyl and R10 is H or an alkyl; R3 and R4 are each independently hydrogen, an alkyl or fluoroalkyl; R5 and R6 are each independently an optional substituent; when p is greater than 0, R" is H and one of said R" is optionally OH; n and p are each an integer from 0 to 6; wherein the term "optional substituent" represents halogen, C1-6alkyl, C1-6heteroalkyl, C2-6alkenyl, C2-6alkynyl, C3-7cycloalkyl, C3-7cycloalkenyl, C6-10aryl-C1-6alkyl, C6-10aryl, C1-6 alkoxy, C2-6alkenyloxy, C2-6alkynyloxy, C3-7cycloalkyloxy, C3-7cycloalkenyloxy, C6-10aryl-C1-6alkyloxy, C6-10aryloxy, -NR40R41, -C NR40R41, -NR40COR41, carboxy, azido, cyano, hydroxyl, nitro, nitroso, -OR40, -SR40, -S 0-2R40, -C R40, --C OR40 and - SO2NR40R41; wherein R40 and R41 are each independently H, halogen, C1-6alkyl, C2-6alkenyl or C2-6alkynyl. A and B are each independently an aryl or heteroaryl; R1 is, an alkyl or cycloalkyl; R2 is absent when the dotted line is a double bond or R2 is hydrogen, an alkyl or cycloalkyl when the dotted line is absent; W is OH when the dotted line is absent or W is O when the dotted line is a double bond; X is O, CH 2, CHR7 or CR7R7, where R7 is in an alkyl or fluoroalkyl; Y is NR10, NR10, O, CH 2, CHR7 or CR7R7, where R7 is in an alkyl or fluoroalkyl and R10 is H or an alkyl; R3 and R4 are each independently hydrogen, an alkyl or fluoroalkyl; R5 and R6 are each independently an optional substituent; when p is greater than 0, R" is H and one of said R" is optionally OH; n and p are each an integer from 0 to 6; wherein the term "optional substituent" represents halogen, C1-6alkyl, C1-6heteroalkyl, C2-6alkenyl, C2-6alkynyl, C3-7cycloalkyl, C3-7cycloalkenyl, C6-10aryl-C1-6alkyl, C6-10aryl, C1-6 alkoxy, C2-6alkenyloxy, C2-6alkynyloxy, C3-7cycloalkyloxy, C3-7cycloalkenyloxy, C6-10aryl-C1-6alkyloxy, C6-10aryloxy, -NR40R41, -C NR40R41, -NR40COR41, carboxy, azido, cyano, hydroxyl, nitro, nitroso, -OR40, -SR40, -S 0-2R40, -C R40, --C OR40 and - SO2NR40R41; wherein R40 and R41 are each independently H, halogen, C1-6alkyl, C2-6alkenyl or C2-6alkynyl.
Pharmaceutical preparation comprising clopidogrel, or a salt or solvate thereof, for use in the treatment of a non-diabetic subject suffering from focal segmental glomerulosclerosis (FSGS).
A crystal of 4,4'-[4-fluoro-7-({4-[4-(3-fluoro-2-methylphenyl)butoxy]phenyl}ethynyl)-2-methyl-1H-indole-1,3-d iyl]dibutanoic acid having at least peaks of about 7.29, 10.24, 12.15, 17.95, and 18.44 at 2θ degree in powdered X-ray diffraction spectrum.
A method for communicating between a first semiconductor die and a second semiconductor die through optical signaling, comprising: converting an electrical signal into an optical signal using an electrical-to-optical transducer located on a face of the first semiconductor die; wherein the first semiconductor die and the second semiconductor die are oriented face-to-face and overlap one another in a communication region so that the optical signal generated on the first semiconductor die shines on the second semiconductor die; receiving the optical signal on a face of the second semiconductor die; and converting the optical signal into a corresponding electrical signal using an optical-to-electrical transducer located on the face of the second semiconductor die; characterized in that after generating the optical signal on the first semiconductor die, the method further comprises passing the optical signal through annuli located within metal layers on the first semiconductor die to focus the optical signal onto the second semiconductor die. converting an electrical signal into an optical signal using an electrical-to-optical transducer located on a face of the first semiconductor die; wherein the first semiconductor die and the second semiconductor die are oriented face-to-face and overlap one another in a communication region so that the optical signal generated on the first semiconductor die shines on the second semiconductor die; receiving the optical signal on a face of the second semiconductor die; and converting the optical signal into a corresponding electrical signal using an optical-to-electrical transducer located on the face of the second semiconductor die; characterized in that after generating the optical signal on the first semiconductor die, the method further comprises passing the optical signal through annuli located within metal layers on the first semiconductor die to focus the optical signal onto the second semiconductor die.
An aqueous suspension comprising elemental biosulfur and at least one surfactant, wherein the average particle size of the sulfur is less than 2.5 micrometer.
A crosslinkable composition comprising a) at least one polyol having free -OH groups, b) at least one polyisocyanate crosslinker having free -NCO groups, c) at least one catalyst for catalysing the reaction between -OH groups of said polyol a) and -NCO groups of said crosslinker b), d) at least one tertiary acid of formula RR'R"CCOOH, wherein each R, R' and R" group, independently, is an alkyl, alkenyl, aryl or aralkyl group containing at least one carbon atom, with the proviso that two or three of the R, R' and R" groups can be linked to form a ring structure and wherein the R, R' and/or R" groups can be substituted, and wherein the total number of carbon atoms in the R, R' and R" groups is the range of from 3 to 40, and e) optionally, at least one complexing agent containing at least one -SH group. a) at least one polyol having free -OH groups, b) at least one polyisocyanate crosslinker having free -NCO groups, c) at least one catalyst for catalysing the reaction between -OH groups of said polyol a) and -NCO groups of said crosslinker b), d) at least one tertiary acid of formula RR'R"CCOOH, wherein each R, R' and R" group, independently, is an alkyl, alkenyl, aryl or aralkyl group containing at least one carbon atom, with the proviso that two or three of the R, R' and R" groups can be linked to form a ring structure and wherein the R, R' and/or R" groups can be substituted, and wherein the total number of carbon atoms in the R, R' and R" groups is the range of from 3 to 40, and e) optionally, at least one complexing agent containing at least one -SH group.
A method, comprising: establishing a first network data bearer, the first network data bearer having a first combination of values for two or more Quality of Service, QoS, parameters; determining that the first combination of values corresponds to a first radio access technology; in response to determining that the first combination of values corresponds to the first radio access technology, steering data of the first network data bearer through a first base station that uses the first radio access technology; establishing a second network data bearer, the second network data bearer having a second combination of values for the two or more QoS parameters; determining that a first signal quality associated with the first base station exceeds a signal quality threshold; determining that the second combination of values corresponds to a second radio access technology; determining that a data queue for the second network data bearer satisfies one or more criteria; and in response to determining that the first signal quality exceeds the signal quality threshold, the second combination of values corresponds to the second radio access technology, and determining that the data queue for the second network data bearer is greater than a threshold, steering a first portion of data of the second network data bearer through a second base station that uses the second radio access technology and a second portion of the data of the second network data bearer through the first base station. establishing a first network data bearer, the first network data bearer having a first combination of values for two or more Quality of Service, QoS, parameters; determining that the first combination of values corresponds to a first radio access technology; in response to determining that the first combination of values corresponds to the first radio access technology, steering data of the first network data bearer through a first base station that uses the first radio access technology; establishing a second network data bearer, the second network data bearer having a second combination of values for the two or more QoS parameters; determining that a first signal quality associated with the first base station exceeds a signal quality threshold; determining that the second combination of values corresponds to a second radio access technology; determining that a data queue for the second network data bearer satisfies one or more criteria; and in response to determining that the first signal quality exceeds the signal quality threshold, the second combination of values corresponds to the second radio access technology, and determining that the data queue for the second network data bearer is greater than a threshold, steering a first portion of data of the second network data bearer through a second base station that uses the second radio access technology and a second portion of the data of the second network data bearer through the first base station.
A micromachined microvalve (600, 800), comprising: a fluid channel plate(650, 850) with a top surface and a bottom surface with one or more inlet ports, and one or more outlet ports connecting said surfaces; and a membrane plate (630, 830) with a top surface and a bottom surface wherein said bottom surface is attached to said top surface of said fluid channel plate (650, 850), said membrane plate including a displaceable membrane portion to selectively obstruct one or more of said inlet ports of said fluid channel plate (650, 850); and means for proportionately actuating said displaceable membrane portion attached to said top surface of said membrane plate, characterized in that the top surface orifice periphery of the one or more inlet ports of the fluid channel plate (650, 850) contains a plurality of convolutions or a sinusoidal configuration. a fluid channel plate(650, 850) with a top surface and a bottom surface with one or more inlet ports, and one or more outlet ports connecting said surfaces; and a membrane plate (630, 830) with a top surface and a bottom surface wherein said bottom surface is attached to said top surface of said fluid channel plate (650, 850), said membrane plate including a displaceable membrane portion to selectively obstruct one or more of said inlet ports of said fluid channel plate (650, 850); and means for proportionately actuating said displaceable membrane portion attached to said top surface of said membrane plate, characterized in that the top surface orifice periphery of the one or more inlet ports of the fluid channel plate (650, 850) contains a plurality of convolutions or a sinusoidal configuration.
A method, comprising: sending, by a user equipment, UE, and to a first network node, a first message including at least one mission critical user identity associated with the UE; characterised by receiving, from the first network node, a second message indicating that the UE can request access point name, APN, information of a packet data network, PDN, for mission critical services; sending, by the UE and to a second network node, a third message requesting the APN information; and receiving, from the second network node, a fourth message including the APN information. sending, by a user equipment, UE, and to a first network node, a first message including at least one mission critical user identity associated with the UE; characterised by receiving, from the first network node, a second message indicating that the UE can request access point name, APN, information of a packet data network, PDN, for mission critical services; sending, by the UE and to a second network node, a third message requesting the APN information; and receiving, from the second network node, a fourth message including the APN information.
A method of identifying a subject as a candidate for treating a disease with a therapeutic agent, the method comprising: (a) determining by ribosomal profiling a first translational profile for a plurality of genes in a sample from a subject having or suspected of having a disease selected from a cancer, an inflammatory disease, an autoimmune disease, a neurodegenerative disease, a neurodevelopmental disease, and a metabolic disease; (b) determining by ribosomal profiling a second translational profile for a plurality of genes in a control sample, wherein the control sample is from a subject known to respond to the therapeutic agent and wherein the sample has not been contacted with the therapeutic agent; and (c) identifying the subject as a candidate for treating the disease with the therapeutic agent when the first translational profile is comparable to the second translational profile. (a) determining by ribosomal profiling a first translational profile for a plurality of genes in a sample from a subject having or suspected of having a disease selected from a cancer, an inflammatory disease, an autoimmune disease, a neurodegenerative disease, a neurodevelopmental disease, and a metabolic disease; (b) determining by ribosomal profiling a second translational profile for a plurality of genes in a control sample, wherein the control sample is from a subject known to respond to the therapeutic agent and wherein the sample has not been contacted with the therapeutic agent; and (c) identifying the subject as a candidate for treating the disease with the therapeutic agent when the first translational profile is comparable to the second translational profile.
A specific binding molecule that binds to Annexin-1 (Anx-A1) for use in the treatment of obsessive compulsive disorder or anxiety, wherein the specific binding molecule is an antibody or fragment thereof.
A method for cell configuration at a base station of a wireless network with a plurality of carriers, the method comprising: generating a common cell from a first plurality of sectors at a first carrier of the plurality of carriers; identifying one or more high-traffic sectors, from a second plurality of sectors at a second carrier of the plurality of carriers, by monitoring a traffic volume of each of the second plurality of sectors, each of the identified one or more high-traffic sectors having a traffic volume higher than a predetermined threshold; generating one or more independent high-traffic cells from the identified one or more high-traffic sectors; and causing a terminal device to be connected to the common cell or to a high-traffic cell of the one or more independent high-traffic cells based at least on a traffic volume of the terminal device, wherein the first plurality of sectors at least partially overlaps with the second plurality of sectors. generating a common cell from a first plurality of sectors at a first carrier of the plurality of carriers; identifying one or more high-traffic sectors, from a second plurality of sectors at a second carrier of the plurality of carriers, by monitoring a traffic volume of each of the second plurality of sectors, each of the identified one or more high-traffic sectors having a traffic volume higher than a predetermined threshold; generating one or more independent high-traffic cells from the identified one or more high-traffic sectors; and causing a terminal device to be connected to the common cell or to a high-traffic cell of the one or more independent high-traffic cells based at least on a traffic volume of the terminal device, wherein the first plurality of sectors at least partially overlaps with the second plurality of sectors.
An apparatus comprising at least one processor and at least one non-transitory memory including program code, the at least one non-transitory memory and the program code configured to, with the processor, cause the apparatus to: access table data associated with a group-based communication resource identifier in a group-based communication repository, wherein the table data associated with the group-based communication resource identifier comprises at least two user identifiers associated with different organization identifiers; in response to determining that the table data associated with the shared group-based communication resource identifier does not comprise treaty data associating the different organization identifiers, transmit a treaty authorization interface to a first client device (108A-N) associated with a first user identifier of the at least two user identifiers; and in response to receiving, from the first client device, a first authorization confirmation associated with the treaty authorization interface, update in the group-based communication repository the table data associated with the group-based communication resource identifier with treaty data associated with the different organization identifiers. access table data associated with a group-based communication resource identifier in a group-based communication repository, wherein the table data associated with the group-based communication resource identifier comprises at least two user identifiers associated with different organization identifiers; in response to determining that the table data associated with the shared group-based communication resource identifier does not comprise treaty data associating the different organization identifiers, transmit a treaty authorization interface to a first client device (108A-N) associated with a first user identifier of the at least two user identifiers; and in response to receiving, from the first client device, a first authorization confirmation associated with the treaty authorization interface, update in the group-based communication repository the table data associated with the group-based communication resource identifier with treaty data associated with the different organization identifiers.
A coating composition comprising (a) one or more binder, and (b) one or more water-insoluble biocide, characterized in that said composition further comprises (c) particles comprising polymer, wherein said particles have specific surface area, measured using the BET method with nitrogen as the adsorbed substance, of 900 m 2 /g or more. (a) one or more binder, and (b) one or more water-insoluble biocide, characterized in that said composition further comprises (c) particles comprising polymer, wherein said particles have specific surface area, measured using the BET method with nitrogen as the adsorbed substance, of 900 m 2 /g or more.
Filling system for a container for storing solid particles, comprising a distribution device for solid particles for receiving and selectively distributing the solid particles towards a dispensing device, and comprising at least one divider element dividing streams of solid particles, the dispensing device comprising at least one scattering element for homogeneously filling the container with solid particles, characterized in that the divider element is rotatably mounted about an axis substantially parallel to the direction of flow of the stream of solid particles in the distribution device in order to allocate any defect in the flow of the solid particles in the distribution device.