mhurhangee/ep-ind-claims huggingface dataset:
A method of testing whether a patient suffering of diffuse large B-cell lymphoma will respond or not to a DNA repair pathway inhibitor comprising: i) determining the expression level (ELi) of several G 1 -G n from table A in a biological sample obtained from said patient ii) comparing the expression level (ELi) determined at step i) with a predetermined reference level (ELRi) iii) calculating the DNARS score trough the following formula DNARS = ∑ i = 1 n βi × Ci wherein βi represent the regression coefficient reference value for the gene G i and Ci = 1 if the expression of the gene Gi (ELi) is higher than the predetermined reference level (ELRi) or Ci = -1 if the expression of the gene (ELi) is lower than or equal to the predetermined reference level (ELRi) iv) comparing the score DNARS determined at step iii) with a predetermined reference value DNARS R v) and concluding that the patient will respond to the DNA repair pathway inhibitor when the DNARS score is higher than the predetermined reference value DNARS R or concluding that the patient will not respond to the DNA repair pathway inhibitor when the DNARS score is lower than the predetermined reference value DNARS R. i) determining the expression level (ELi) of several G 1 -G n from table A in a biological sample obtained from said patient ii) comparing the expression level (ELi) determined at step i) with a predetermined reference level (ELRi) iii) calculating the DNARS score trough the following formula DNARS = ∑ i = 1 n βi × Ci wherein βi represent the regression coefficient reference value for the gene G i and Ci = 1 if the expression of the gene Gi (ELi) is higher than the predetermined reference level (ELRi) or Ci = -1 if the expression of the gene (ELi) is lower than or equal to the predetermined reference level (ELRi) iv) comparing the score DNARS determined at step iii) with a predetermined reference value DNARS R v) and concluding that the patient will respond to the DNA repair pathway inhibitor when the DNARS score is higher than the predetermined reference value DNARS R or concluding that the patient will not respond to the DNA repair pathway inhibitor when the DNARS score is lower than the predetermined reference value DNARS R.
At least one computer readable medium having instructions stored therein for estimating an inter-node interference signal, the instructions when executed on a machine to cause the machine to: receive downlink signal information at a victim node from an aggressor node, wherein the downlink signal information is received via X2 signaling or backhaul link signaling via a wired connection or an optical fiber connection; estimate a channel impulse response for the channel between the aggressor node and the victim node using the downlink signal information; and estimate the inter-node interference signal for the channel using the downlink signal information and the channel impulse response. receive downlink signal information at a victim node from an aggressor node, wherein the downlink signal information is received via X2 signaling or backhaul link signaling via a wired connection or an optical fiber connection; estimate a channel impulse response for the channel between the aggressor node and the victim node using the downlink signal information; and estimate the inter-node interference signal for the channel using the downlink signal information and the channel impulse response.
A yarn winder producing a package (Pw) by winding a yarn onto a bobbin (Bw) while reciprocally moving, in a predetermined traverse direction, a traverse guide to which the yarn is threaded, the yarn winder comprising: a guide driving unit which is configured to reciprocally move the traverse guide in the traverse direction; and a controller which is configured to control the guide driving unit, wherein the controller is able to perform: normal control of reversing the traverse guide at a predetermined regular position (Ts); and creeping control of reversing the traverse guide at at least one creeping position (T1-T4) which is in a creeping region that is distanced inward from the regular position (Ts) by a predetermined distance, and for each reciprocal movement of the traverse guide, the controller is able to determine either the normal control or the creeping control is performed, characterized in that the predetermined distance is 10 mm or more and 30 mm or less. a guide driving unit which is configured to reciprocally move the traverse guide in the traverse direction; and a controller which is configured to control the guide driving unit, wherein the controller is able to perform: normal control of reversing the traverse guide at a predetermined regular position (Ts); and creeping control of reversing the traverse guide at at least one creeping position (T1-T4) which is in a creeping region that is distanced inward from the regular position (Ts) by a predetermined distance, and for each reciprocal movement of the traverse guide, the controller is able to determine either the normal control or the creeping control is performed, characterized in that the predetermined distance is 10 mm or more and 30 mm or less. normal control of reversing the traverse guide at a predetermined regular position (Ts); and creeping control of reversing the traverse guide at at least one creeping position (T1-T4) which is in a creeping region that is distanced inward from the regular position (Ts) by a predetermined distance, and for each reciprocal movement of the traverse guide, the controller is able to determine either the normal control or the creeping control is performed, characterized in that the predetermined distance is 10 mm or more and 30 mm or less.
A method, comprising: rebasing a module in a virtual partition to load at a fixed address; storing a first hash of a page of memory associated with the fixed address; wherein storing the first hash comprises identifying a code portion and a data portion of the page and storing only a hash of the code portion; receiving in an external handler a notification associated with an event affecting the page, said notification indicating a write operation to the page at an address; instructing an internal agent within the virtual partition to execute a task and return results based on the task to the external handler, wherein the task comprises determining if the address is in a code section or a data section of the page; and in response to determining that the address is in a code section, rehashing the page and taking a policy action based on the results returned by the internal agent if a second hash created from rehashing differs from the first hash. rebasing a module in a virtual partition to load at a fixed address; storing a first hash of a page of memory associated with the fixed address; wherein storing the first hash comprises identifying a code portion and a data portion of the page and storing only a hash of the code portion; receiving in an external handler a notification associated with an event affecting the page, said notification indicating a write operation to the page at an address; instructing an internal agent within the virtual partition to execute a task and return results based on the task to the external handler, wherein the task comprises determining if the address is in a code section or a data section of the page; and in response to determining that the address is in a code section, rehashing the page and taking a policy action based on the results returned by the internal agent if a second hash created from rehashing differs from the first hash.
A method of optimizing metering profiles of electromagnetically driven displacement pumps, in which a moveable displacer element delimits a metering chamber which is connected by way of valves to a suction and a pressure line so that delivery fluid can alternately be sucked into the metering chamber by way of the suction line and urged out of the metering chamber by way of the pressure line by an oscillating movement of the displacer element, wherein the delivery fluid flow into the pressure line represents the metering profile and there is provided a drive for the oscillating movement of the displacer element, characterised in that a model-based closed-loop control is used for the drive, wherein the position of the displacer element and/or the current through the electromagnetic drive is measured and a state space model is used for the model-based closed-loop control, which state space model uses the position of the displacer element and/or the current through the electromagnetic drive as measurement variables.
A method of separating a crystal comprising, in a dry fractionation of oil-and-fat, adding a filtration aid to crystal slurry after crystallization in an amount of 15 to 80% by weight with respect to a crystal amount in the crystal slurry, and then mixing with each other, and subjecting the mixture to press-filtering, wherein the crystal amount in the crystal slurry is 10 to 35% by weight as a solid fat content at a temperature of the crystal slurry.
A patient interface for nasal CPAP therapy of sleep disordered breathing, the patient interface comprising: a frame having a main body and a pair of side frame members formed in one piece with the main body; a cushion removably attached to the frame such that the cushion and the frame are repeatably engagable with and disengagable from one another; and characterised by: two locking clips, each formed as an integral unit with the frame at a respective side frame member; and a headgear assembly comprising a pair of front straps and yokes, wherein each yoke is attached to a front strap, and wherein each yoke is configured to be removably connected to a locking clip, wherein when connected to the locking clip, the respective yoke is rotationally adjustable with respect to the locking clip by way of a toothed system, and wherein the yoke and the respective locking clip are removable from each other only when the yoke and the locking clip are positioned at a position that does not occur when the patient interface is in normal use. a frame having a main body and a pair of side frame members formed in one piece with the main body; a cushion removably attached to the frame such that the cushion and the frame are repeatably engagable with and disengagable from one another; and characterised by: two locking clips, each formed as an integral unit with the frame at a respective side frame member; and a headgear assembly comprising a pair of front straps and yokes, wherein each yoke is attached to a front strap, and wherein each yoke is configured to be removably connected to a locking clip, two locking clips, each formed as an integral unit with the frame at a respective side frame member; and a headgear assembly comprising a pair of front straps and yokes, wherein each yoke is attached to a front strap, and wherein each yoke is configured to be removably connected to a locking clip, wherein when connected to the locking clip, the respective yoke is rotationally adjustable with respect to the locking clip by way of a toothed system, and wherein the yoke and the respective locking clip are removable from each other only when the yoke and the locking clip are positioned at a position that does not occur when the patient interface is in normal use.
A joining device for parts of furniture and furnishing accessories, of the shelf unit, bookcase, drawer unit, bed frame, seating type and the like, comprising a casing or container body suitable for being inserted in a seat formed in one of the components of the item of furniture to be joined and provided with an expansion bushing externally projecting with respect to a first end or front end of said casing or container body and suitable for engaging with a further seat of a further component of the item of furniture to be joined to the component wherein the casing or container body is inserted, said joining device characterised in that it comprises a cam mechanism for a linear motion of actuation means co-operating in an expansion and retraction deformation movement of the expansion bushing and simultaneous expansion of at least one portion of said casing or container body, with said cam mechanism and actuation means housed in the casing or container body and actuated by a tool, said actuation means comprise a slider, driven in translation by said cam mechanism, to which slider said expansion bushing is made integral, co-operating with a wedge-shaped protuberance of the casing or container body for its simultaneous expansion and retraction movement, said slider having a wedge-shaped rear part for expansion of said at least one portion of said casing or container body following its linear movement, characterised in that said expansion bushing has a substantially cylindrical shank in which a slot is formed, apt to be engaged by a protuberance of the slider, a pair of lateral wings being projected at the front from said shank, distanced so as to define an empty space apt to receive said protuberance of the container body, respective thickened portions with outer teeth being provided frontally to the wings.
Method for calibrating a position sensor (30, 31, 32, 33, 34, 37, 38, 39, 45, 46, 47) that can be used to detect the position of an equipment component (12, 13, 14) of a mobile working machine, the position sensor detecting the position of the equipment component (12, 13, 14) relative to another equipment component (12, 13, 14) or relative to the working machine, having the following method steps: - selecting at least two positions of the equipment component (12, 13, 14) and preliminarily determining the distance of the at least two positions of the equipment component (12, 13, 14) from one another; - the position sensor (30, 31, 32, 33, 34, 37, 38, 39, 45, 46, 47) independently identifying the at least two positions of the equipment component (12, 13, 14); - ascertaining calibration parameters for the position sensor (30, 31, 32, 33, 34, 37, 38, 39, 45, 46, 47) from the signals delivered by the position sensor in the at least two positions of the equipment component (12, 13, 14) and the preliminarily determined distance between the at least two positions. - selecting at least two positions of the equipment component (12, 13, 14) and preliminarily determining the distance of the at least two positions of the equipment component (12, 13, 14) from one another; - the position sensor (30, 31, 32, 33, 34, 37, 38, 39, 45, 46, 47) independently identifying the at least two positions of the equipment component (12, 13, 14); - ascertaining calibration parameters for the position sensor (30, 31, 32, 33, 34, 37, 38, 39, 45, 46, 47) from the signals delivered by the position sensor in the at least two positions of the equipment component (12, 13, 14) and the preliminarily determined distance between the at least two positions.
A uniaxial pedicle screw sub-assembly comprising: a bone screw having a threaded bone shaft adapted for insertion in a vertebra; a uniaxial inner collet configured in an operative position to clamp about a head of the bone screw, said head being substantially ball-shaped with a truncated surface arranged to cooperate with a bearing surface of the uniaxial inner collet in an inoperative position to permit tilting of the uniaxial inner collet about a tilt axis of the head of the bone screw; a seat arranged to provide seating for retention of the uniaxial inner collet, the seat designed to tilt in conjunction with the uniaxial inner collet in the inoperative position about the tilt axis of the head of said bone screw; an inner collet actuator designed to engage the seat to activate the uniaxial inner collet for movement into the operative position for clamping about the head of the bone screw to lock the uniaxial inner collet and the seat to the head of said bone screw; the seat including a recess within which the uniaxial inner collet seats for retention in either the inoperative or operative positions, the uniaxial inner collet being movable via the inner collet actuator from i) the inoperative position where the head of the bone screw is received within the uniaxial inner collet with radial separation of the uniaxial inner collet into the recess of the seat, to ii) the operative position where the head of the bone screw is clamped within the uniaxial inner collet. a bone screw having a threaded bone shaft adapted for insertion in a vertebra; a uniaxial inner collet configured in an operative position to clamp about a head of the bone screw, said head being substantially ball-shaped with a truncated surface arranged to cooperate with a bearing surface of the uniaxial inner collet in an inoperative position to permit tilting of the uniaxial inner collet about a tilt axis of the head of the bone screw; a seat arranged to provide seating for retention of the uniaxial inner collet, the seat designed to tilt in conjunction with the uniaxial inner collet in the inoperative position about the tilt axis of the head of said bone screw; an inner collet actuator designed to engage the seat to activate the uniaxial inner collet for movement into the operative position for clamping about the head of the bone screw to lock the uniaxial inner collet and the seat to the head of said bone screw; the seat including a recess within which the uniaxial inner collet seats for retention in either the inoperative or operative positions, the uniaxial inner collet being movable via the inner collet actuator from i) the inoperative position where the head of the bone screw is received within the uniaxial inner collet with radial separation of the uniaxial inner collet into the recess of the seat, to ii) the operative position where the head of the bone screw is clamped within the uniaxial inner collet.
A drug-coated balloon catheter comprising a catheter shaft, a tubular expansion protection with a sealing of the space between the catheter shaft and the tubular expansion protection against the penetration of bodily fluids and a catheter balloon, wherein the expansion protection protects against premature expansion and premature loss of coating material up to the expansion of the catheter balloon, wherein the expansion protection can optionally contain or comprise a self-expanding stent, characterized in that the expansion protection is closed distally by pharmaceutically and physiologically safe, soluble substances.
A mechanochemical method for obtaining of cyclic peptides, characterized in that it is linear tetrapeptides with a forced pseudocyclic conformation with closely located active reactive carboxyl and amino termini of the formulas 1-4 is subjected to grinding in the presence of a coupling reagent and a base for 1 to 3 hours, after which the ground raw post-reaction mixture is washed several times with water.
A medical imaging system, comprising - a medical imaging device for medical imaging of a patient, - an in-vitro-diagnostic device for in-vitro-diagnostic testing of a sample, - a control device, wherein the control device is portable and configured to operate the medical imaging device, wherein the control device is further configured to operate the in-vitro-diagnostic device, - a docking station, wherein the docking station is portable and arranged separately from the medical imaging device, wherein the docking station comprises a docking structure for accommodating the control device in a releasable form-fitting manner, wherein the docking structure comprises the in-vitro-diagnostic device. - a medical imaging device for medical imaging of a patient, - an in-vitro-diagnostic device for in-vitro-diagnostic testing of a sample, - a control device, wherein the control device is portable and configured to operate the medical imaging device, wherein the control device is further configured to operate the in-vitro-diagnostic device, - a docking station, wherein the docking station is portable and arranged separately from the medical imaging device, wherein the docking station comprises a docking structure for accommodating the control device in a releasable form-fitting manner, wherein the docking structure comprises the in-vitro-diagnostic device.
Boiler comprising a combustion chamber which can be loaded with lumpy fuel, an ash space, wherein the combustion chamber is arranged above the ash space, and comprising a heat exchanger which is arranged downstream of the combustion chamber and comprises a down-swept flue and an upward gas passage (6, 7) for the combustion gases, comprising a deflection chamber, which connects the down-swept flue and the upward gas passage (6, 7) and forms a separator for fly ash, adjoining the ash space and comprising two screw conveyors (10, 11) which convey into a common collecting vessel and extend transversely to a partition wall between the deflecting chamber and ash space, on the one hand for the ash space and on the other hand for the deflection chamber, wherein the two screw conveyors (10, 11) have a common screw shaft, the partition wall has a tubular lead-through for the screw shaft between the deflection chamber and the ash space, characterised in that the lead-through passes through or supports a retaining wall in the region of the end of the lead-through at the front in the conveying direction, and in that the lead-through forms, between the retaining wall and the end, which engages into the lead-through, of the screw conveyor at the rear in the conveying direction, a retaining space comprising an outlet which issues into the conveying region of the screw conveyor which is at the front in the conveying direction and adjoins the retaining wall.
Locking device for locking a functionally essential component of a motor vehicle, in particular for locking a steering shaft, with a first housing part in which a locking bolt is received movably between a locking position for locking the functionally essential component and a release position for releasing the functionally essential component, and a second housing part in which means (11, 12) for moving the locking bolt between the locking position and the release position are received, wherein a safety unit (6, 7) is provided on the first housing part, which in an engaged position prevents movement of the locking bolt when the first housing part is changed in its arrangement relative to the second housing part, and in a retracted position releases a movement of the locking bolt when the first housing part is arranged on the second housing part, wherein a release element is provided in order to support a transfer of the safety unit (6, 7) from the retracted position into the engaged position in the event of manipulations of the first housing part and/or the second housing part, characterized in that the safety unit (6, 7) comprises a locking element which can be latched to the locking bolt in the engaged position of the safety unit (6, 7) and which is spaced apart from the locking bolt in the retracted position of the safety unit (6, 7), and in that the safety unit (6, 7) comprises a holding element which, in the retracted position of the safety unit (6, 7), holds the locking element at a distance from the locking bolt and, in the engaged position of the safety unit (6, 7), releases the locking element for mechanical engagement with the locking bolt, wherein the holding element is designed as a spring element and comprises a spring-elastic pretension when the first housing part is arranged on the second housing part.