A synthetic foam, said synthetic foam comprising: a biodegradable phase-separated polyurethane comprising an amorphous segment and a crystalline segment, wherein at least said amorphous segment comprises a hydrophilic segment, said phase-separated polyurethane having the following formula: [R-Q 1 [-R'-Z 1 -[R"-Z 2 -R′′′-Z 3] p -R"-Z 4] q -R'-Q 2] n wherein: R is a polymer or copolymer selected from one or more aliphatic polyesters, polyether esters, polyethers, polyanhydrides, and/or polycarbonates, and at least one R comprises said hydrophilic segment; R', R", and R′′′ are independently C 2 -C 8 alkylene, optionally substituted with C 1 -C 10 alkyl or C 1 -C 10 alkyl groups substituted with protected S, N, P or O moieties and/or comprising S, N, P or O in said alkylene chain; Z 1 -Z 4 are independently amide, urea or urethane; Q 1 and Q 2 are independently urea, urethane, amide, carbonate, ester or anhydride; n is an integer from 5-500; and p and q are independently 0 or 1; and wherein the synthetic foam is characterized in that it comprises hemostatic particles which are homogeneously distributed within said foam, wherein said particles are solid, insoluble and hydrophilic; and wherein said foam is prepared by dissolving at least said phase-separated polyurethane in one or more solvents to form a solution; contacting said hemostatic particles with said solution to form a mixture comprising said phase-separated polyurethane and said hemostatic particles; freeze-drying said mixture by: freezing said mixture; and subsequently subliming said one or more solvents to form said synthetic foam comprising said homogeneous distribution of said hemostatic particles. a biodegradable phase-separated polyurethane comprising an amorphous segment and a crystalline segment, wherein at least said amorphous segment comprises a hydrophilic segment, said phase-separated polyurethane having the following formula: [R-Q 1 [-R'-Z 1 -[R"-Z 2 -R′′′-Z 3] p -R"-Z 4] q -R'-Q 2] n wherein: R is a polymer or copolymer selected from one or more aliphatic polyesters, polyether esters, polyethers, polyanhydrides, and/or polycarbonates, and at least one R comprises said hydrophilic segment; R', R", and R′′′ are independently C 2 -C 8 alkylene, optionally substituted with C 1 -C 10 alkyl or C 1 -C 10 alkyl groups substituted with protected S, N, P or O moieties and/or comprising S, N, P or O in said alkylene chain; Z 1 -Z 4 are independently amide, urea or urethane; Q 1 and Q 2 are independently urea, urethane, amide, carbonate, ester or anhydride; n is an integer from 5-500; and R is a polymer or copolymer selected from one or more aliphatic polyesters, polyether esters, polyethers, polyanhydrides, and/or polycarbonates, and at least one R comprises said hydrophilic segment; R', R", and R′′′ are independently C 2 -C 8 alkylene, optionally substituted with C 1 -C 10 alkyl or C 1 -C 10 alkyl groups substituted with protected S, N, P or O moieties and/or comprising S, N, P or O in said alkylene chain; Z 1 -Z 4 are independently amide, urea or urethane; Q 1 and Q 2 are independently urea, urethane, amide, carbonate, ester or anhydride; n is an integer from 5-500; and p and q are independently 0 or 1; and wherein the synthetic foam is characterized in that it comprises hemostatic particles which are homogeneously distributed within said foam, wherein said particles are solid, insoluble and hydrophilic; and wherein said foam is prepared by dissolving at least said phase-separated polyurethane in one or more solvents to form a solution; contacting said hemostatic particles with said solution to form a mixture comprising said phase-separated polyurethane and said hemostatic particles; freeze-drying said mixture by: freezing said mixture; and subsequently subliming said one or more solvents to form said synthetic foam comprising said homogeneous distribution of said hemostatic particles. freezing said mixture; and subsequently subliming said one or more solvents to form said synthetic foam comprising said homogeneous distribution of said hemostatic particles.