A method for establishing a fouling-release coating system on a surface of a substrate comprising the sequential steps of; a. optionally applying one or more layers of a primer composition onto the surface of said substrate and allowing said layer(s) to cure, thereby forming a primed substrate; b. applying one or more layers of silicone-containing tie-coat composition in liquid form, onto the surface of said primed substrate or said substrate, and allowing said layer(s) to cure, thereby forming a cured tie-coat layer; c. applying one or more layers of a fouling-release coating composition onto said cured tie-coat layer, wherein said fouling-release coating composition comprises a condensation-curable polysiloxane-based binder matrix constituting at least 40 % by dry weight of said coating composition, wherein more than 65 % by weight of said binder matrix is represented by polysiloxane parts, and allowing said fouling-release coating composition to cure; wherein said tie-coat composition and/or said fouling-release coating composition comprises constituents having poly(oxyalkylene) chains, and wherein said tie-coat composition and/or said fouling-release coating composition further comprises one or more sterically hindered amines, wherein the sterically hindered amines are hindered amine moieties of the general formula I: wherein each R1 is independently linear or branched C 1 -C 4 alkyl; R2 is selected from -H, optionally substituted linear or branched C 1-30 -alkyl, optionally substituted linear or branched C 2-30 -alkenyl, optionally substituted aryl, -OH, optionally substituted linear or branched C 1-30 -alkoxy, optionally substituted linear or branched C 1-30 -alkenyloxy, optionally substituted aryloxy, optionally substituted linear or branched C 1-30 -alkylcarbonyl, optionally substituted C 1-30 -alkenylcarbonyl, and optionally substituted arylcarbonyl; R3 is an optionally substituted divalent group forming an N-heterocyclic 5-, 6- or 7-membered ring together with the intervening -C 2 -N -C 2 -group, or R3 as defined herein is linked to one or more hindered amine moieties each independently having the general formula I. a. optionally applying one or more layers of a primer composition onto the surface of said substrate and allowing said layer(s) to cure, thereby forming a primed substrate; b. applying one or more layers of silicone-containing tie-coat composition in liquid form, onto the surface of said primed substrate or said substrate, and allowing said layer(s) to cure, thereby forming a cured tie-coat layer; c. applying one or more layers of a fouling-release coating composition onto said cured tie-coat layer, wherein said fouling-release coating composition comprises a condensation-curable polysiloxane-based binder matrix constituting at least 40 % by dry weight of said coating composition, wherein more than 65 % by weight of said binder matrix is represented by polysiloxane parts, and allowing said fouling-release coating composition to cure; wherein said tie-coat composition and/or said fouling-release coating composition comprises constituents having poly(oxyalkylene) chains, and wherein said tie-coat composition and/or said fouling-release coating composition further comprises one or more sterically hindered amines, wherein the sterically hindered amines are hindered amine moieties of the general formula I: wherein each R1 is independently linear or branched C 1 -C 4 alkyl; R2 is selected from -H, optionally substituted linear or branched C 1-30 -alkyl, optionally substituted linear or branched C 2-30 -alkenyl, optionally substituted aryl, -OH, optionally substituted linear or branched C 1-30 -alkoxy, optionally substituted linear or branched C 1-30 -alkenyloxy, optionally substituted aryloxy, optionally substituted linear or branched C 1-30 -alkylcarbonyl, optionally substituted C 1-30 -alkenylcarbonyl, and optionally substituted arylcarbonyl; R3 is an optionally substituted divalent group forming an N-heterocyclic 5-, 6- or 7-membered ring together with the intervening -C 2 -N -C 2 -group, or R3 as defined herein is linked to one or more hindered amine moieties each independently having the general formula I. each R1 is independently linear or branched C 1 -C 4 alkyl; R2 is selected from -H, optionally substituted linear or branched C 1-30 -alkyl, optionally substituted linear or branched C 2-30 -alkenyl, optionally substituted aryl, -OH, optionally substituted linear or branched C 1-30 -alkoxy, optionally substituted linear or branched C 1-30 -alkenyloxy, optionally substituted aryloxy, optionally substituted linear or branched C 1-30 -alkylcarbonyl, optionally substituted C 1-30 -alkenylcarbonyl, and optionally substituted arylcarbonyl; R3 is an optionally substituted divalent group forming an N-heterocyclic 5-, 6- or 7-membered ring together with the intervening -C 2 -N -C 2 -group, or R3 as defined herein is linked to one or more hindered amine moieties each independently having the general formula I.