A compound of formula (I'): wherein ▪ R 1, each identical or different, is chosen from the group consisting of halogen, R, OR, NRR, CN, CF 3, C R, C OR, C NRR', NO 2, (C 1 -C 6)alkylene-OR, (C 1 -C 6)alkylene-NRR', (C 1 -C 6)alkylene-CO 2 R, (C 1 -C 6)alkylene-CONRR', -O-(C 1 -C 6)alkylene-CO 2 R, -O-(C 1 -C 6)alkylene-CONRR', CO 2 -(C 1 -C 6)alkylene-OR, CO 2 -(C 1 -C 6)alkylene-NRR', C NH-(C 1 -C 6)alkylene-OR, CONH-(C 1 -C 6)alkylene-NRR', OCF 3, SO 2 R, SO 3 H, SO 2 NRR', NHSO 2 R, R 10 C≡CR 11, (R 10)(R 11)C=C(R 11) 2, (C 1 -C 6)alkylene-COR, NHCOR, or (C 1 -C 6)alkyl interrupted by at least one heteroatom chosen from O, N and S; ▪ L 1 is CH 2; ▪ q is 0, 1, 2, 3 or 4 ▪ X' is CR 7; ▪ R 7 is OR; ▪ n is1 or 2; ▪ p is 1, 2 or 3; ▪ R 3, R 4, R 8' and R 8, each identical or different, are chosen in the group consisting of H, linear or branched (C 1 -C 6)alkyl, halogen, OH, -O-(C 1 -C 6)alkyl, NRR', CN, CF 3, OR, C R, C OR or C NRR'; ▪ A is chosen from the group consisting of: - -C -; - -C NH-; ▪ L 2 is linear or branched (C 1 -C 6)alkylene optionally interrupted by at least one heteroatom chosen from O, NR or S and/or optionally substituted by: R, OR, NRR', (C 1 -C 6)alkyl-OR, (C 1 -C 6)alkyl-NRR', OC R, NHC R, NHC NRR', CN, C(=NH)NHOR; ▪ R 6 is chosen from the group consisting in aryl, heteroaryl, cycloalkyl, heterocycle, H, wherein the aryl, heteroaryl, cycloalkyl or heterocycle is mono or polycyclic and is optionally substituted by one or more of linear or branched (C 1 -C 6)alkyl, halogen, NRR, CN, CF 3, OR, =O, C R, C OR, NHC R, OC R, linear or branched (C 2 -C 6)alkenylene or C NRR'; ▪ each R and R', identical or different, are independently chosen from H, linear or branched (C 1 -C 6)alkyl, cycloalkyl, aryl, aromatic or non aromatic heterocycle, linear or branched -(C 1 -C 6)alkyl-aryl or linear or branched -(C 1 -C 6)alkyl-heterocycle, wherein the heterocycle is aromatic or non aromatic; optionally substituted or not by OH, CO 2 H, C NH 2, NH 2 ▪ R 10 independently is chosen from a bond, a linear or branched (C 1 -C 6)alkyl; ▪ R 11 independently is chosen from an hydrogen atom, a linear or branched (C 1 -C 6)alkyl or an aryl, the alkyl or aryl is optionally substituted by OH, NH 2, C OH or C NH; where "aryl" refers to an aromatic monocyclic or multicyclic hydrocarbon ring system of 6 to 14 carbon atoms; where "cycloalkyl" refers to a non-aromatic monocyclic or multicyclic hydrocarbon ring of 3 to 10 carbon atoms; where "heteroaryl" refers to 5 to 14 aromatic hetero, mono-, bi- or multicyclic rings; where "heterocycle" refers to a saturated, partially unsaturated or unsaturated non-aromatic stable 3 to 14 membered, mono-, bi- or multicyclic rings. or their pharmaceutically acceptable salts or their optical isomers, racemates, diastereoisomers, enantiomers or tautomers, with the exception of - q is 0, L 1 is CH 2, X' is CR 7 and R 7 is OH, i is 1, A is C=O, L 2 is C 2 H 4 and R 6 is - q is 1, R 1 is CI at position 7, L 1 is CH 2, X' is CR 7 and R 7 is OH, i is 1, A is C=O, L 2 R 6 is CH(CH 2 CH 3) 2. ▪ R 1, each identical or different, is chosen from the group consisting of halogen, R, OR, NRR, CN, CF 3, C R, C OR, C NRR', NO 2, (C 1 -C 6)alkylene-OR, (C 1 -C 6)alkylene-NRR', (C 1 -C 6)alkylene-CO 2 R, (C 1 -C 6)alkylene-CONRR', -O-(C 1 -C 6)alkylene-CO 2 R, -O-(C 1 -C 6)alkylene-CONRR', CO 2 -(C 1 -C 6)alkylene-OR, CO 2 -(C 1 -C 6)alkylene-NRR', C NH-(C 1 -C 6)alkylene-OR, CONH-(C 1 -C 6)alkylene-NRR', OCF 3, SO 2 R, SO 3 H, SO 2 NRR', NHSO 2 R, R 10 C≡CR 11, (R 10)(R 11)C=C(R 11) 2, (C 1 -C 6)alkylene-COR, NHCOR, or (C 1 -C 6)alkyl interrupted by at least one heteroatom chosen from O, N and S; ▪ L 1 is CH 2; ▪ q is 0, 1, 2, 3 or 4 ▪ X' is CR 7; ▪ R 7 is OR; ▪ n is1 or 2; ▪ p is 1, 2 or 3; ▪ R 3, R 4, R 8' and R 8, each identical or different, are chosen in the group consisting of H, linear or branched (C 1 -C 6)alkyl, halogen, OH, -O-(C 1 -C 6)alkyl, NRR', CN, CF 3, OR, C R, C OR or C NRR'; ▪ A is chosen from the group consisting of: - -C -; - -C NH-; - -C -; - -C NH-; ▪ L 2 is linear or branched (C 1 -C 6)alkylene optionally interrupted by at least one heteroatom chosen from O, NR or S and/or optionally substituted by: R, OR, NRR', (C 1 -C 6)alkyl-OR, (C 1 -C 6)alkyl-NRR', OC R, NHC R, NHC NRR', CN, C(=NH)NHOR; ▪ R 6 is chosen from the group consisting in aryl, heteroaryl, cycloalkyl, heterocycle, H, wherein the aryl, heteroaryl, cycloalkyl or heterocycle is mono or polycyclic and is optionally substituted by one or more of linear or branched (C 1 -C 6)alkyl, halogen, NRR, CN, CF 3, OR, =O, C R, C OR, NHC R, OC R, linear or branched (C 2 -C 6)alkenylene or C NRR'; ▪ each R and R', identical or different, are independently chosen from H, linear or branched (C 1 -C 6)alkyl, cycloalkyl, aryl, aromatic or non aromatic heterocycle, linear or branched -(C 1 -C 6)alkyl-aryl or linear or branched -(C 1 -C 6)alkyl-heterocycle, wherein the heterocycle is aromatic or non aromatic; optionally substituted or not by OH, CO 2 H, C NH 2, NH 2 ▪ R 10 independently is chosen from a bond, a linear or branched (C 1 -C 6)alkyl; ▪ R 11 independently is chosen from an hydrogen atom, a linear or branched (C 1 -C 6)alkyl or an aryl, the alkyl or aryl is optionally substituted by OH, NH 2, C OH or C NH; - q is 0, L 1 is CH 2, X' is CR 7 and R 7 is OH, i is 1, A is C=O, L 2 is C 2 H 4 and R 6 is - q is 1, R 1 is CI at position 7, L 1 is CH 2, X' is CR 7 and R 7 is OH, i is 1, A is C=O, L 2 R 6 is CH(CH 2 CH 3) 2.