A spray-drying process, comprising: (a) delivering a spray solution comprising an active agent and a matrix material in an organic solvent to a spray-drying apparatus, wherein said spray solution is formed by forming a feed suspension comprising said active agent, said matrix material and said organic solvent, wherein said feed suspension is at a temperature T 1, and directing said feed suspension to a heat exchanger, thereby increasing the temperature of said feed suspension to a temperature T 2, wherein (i) temperature T 2 is greater than temperature T 1; and (ii) said spray solution is at a pressure that is greater than the vapor pressure of said solvent at temperature T 2 such that said active agent and said matrix material are soluble in said solvent at temperature T 2, and wherein the residence time of the feed suspension through said heat exchanger is less than 1 minute; (b) atomizing said spray solution into droplets within said spray-drying apparatus via a nozzle to remove at least a portion of the organic solvent from said droplets to form a plurality of particles, wherein said spray solution is delivered to said nozzle at a temperature T 3, wherein temperature T 3 is such that said active agent or said matrix material are not soluble in said solvent at temperature T 3; and (c) collecting said particles, wherein said particles comprise said active agent and said matrix material. (a) delivering a spray solution comprising an active agent and a matrix material in an organic solvent to a spray-drying apparatus, wherein said spray solution is formed by forming a feed suspension comprising said active agent, said matrix material and said organic solvent, wherein said feed suspension is at a temperature T 1, and directing said feed suspension to a heat exchanger, thereby increasing the temperature of said feed suspension to a temperature T 2, wherein (i) temperature T 2 is greater than temperature T 1; and (ii) said spray solution is at a pressure that is greater than the vapor pressure of said solvent at temperature T 2 such that said active agent and said matrix material are soluble in said solvent at temperature T 2, and wherein the residence time of the feed suspension through said heat exchanger is less than 1 minute; forming a feed suspension comprising said active agent, said matrix material and said organic solvent, wherein said feed suspension is at a temperature T 1, and directing said feed suspension to a heat exchanger, thereby increasing the temperature of said feed suspension to a temperature T 2, wherein (i) temperature T 2 is greater than temperature T 1; and (ii) said spray solution is at a pressure that is greater than the vapor pressure of said solvent at temperature T 2 such that said active agent and said matrix material are soluble in said solvent at temperature T 2, and wherein the residence time of the feed suspension through said heat exchanger is less than 1 minute; (b) atomizing said spray solution into droplets within said spray-drying apparatus via a nozzle to remove at least a portion of the organic solvent from said droplets to form a plurality of particles, wherein said spray solution is delivered to said nozzle at a temperature T 3, wherein temperature T 3 is such that said active agent or said matrix material are not soluble in said solvent at temperature T 3; and (c) collecting said particles, wherein said particles comprise said active agent and said matrix material.