mhurhangee/ep-ind-claims huggingface dataset:
A non-transient machine readable medium containing program instructions for causing a neuromodulator configured to be connected to electrodes and deliver neuromodulation energy to one or more neural targets through said electrodes, to: determine target energy allocations for a plurality of said electrodes based on at least one target pole to provide a target sub-perception modulation field; and normalize the target sub-perception modulation field, including determining a time domain scaling factor to account for at least one property of a neural target or of a neuromodulation waveform, and applying the time domain scaling factor to the target energy allocations. determine target energy allocations for a plurality of said electrodes based on at least one target pole to provide a target sub-perception modulation field; and normalize the target sub-perception modulation field, including determining a time domain scaling factor to account for at least one property of a neural target or of a neuromodulation waveform, and applying the time domain scaling factor to the target energy allocations.
A turbine airfoil comprising: a suction sidewall and a pressure sidewall, each sidewall (52, 54) extending spanwise from an airfoil base and extending chordwise between a leading edge and a trailing edge; a tip wall extending chordwise from the leading edge to the trailing edge and joining respective outer spanwise ends of the suction and pressure sidewalls (52, 54); and a plurality of tip leakage control channels distributed across at least a chordwise portion of the tip wall between the airfoil leading edge and the airfoil trailing edge, each channel recessed into an outer surface of the tip wall, an inlet of each tip leakage control channel beginning proximate a junction of the airfoil pressure sidewall and the tip wall, an outlet of each tip leakage control channel terminating at a recessed portion of a junction of the tip wall and the suction sidewall, a portion of each tip leakage control channel is curved toward the trailing edge from the inlet to the outlet; and characterised in that the outer surface includes a tip rib extending chordwise along at least a portion of a pressure side of the tip wall between the airfoil leading edge and airfoil trailing edge; and in that the channel inlets are aligned with tip rib along a chordwise path at the pressure side of the tip wall between the airfoil leading edge and airfoil trailing edge. a suction sidewall and a pressure sidewall, each sidewall (52, 54) extending spanwise from an airfoil base and extending chordwise between a leading edge and a trailing edge; a tip wall extending chordwise from the leading edge to the trailing edge and joining respective outer spanwise ends of the suction and pressure sidewalls (52, 54); and a plurality of tip leakage control channels distributed across at least a chordwise portion of the tip wall between the airfoil leading edge and the airfoil trailing edge, each channel recessed into an outer surface of the tip wall, an inlet of each tip leakage control channel beginning proximate a junction of the airfoil pressure sidewall and the tip wall, an outlet of each tip leakage control channel terminating at a recessed portion of a junction of the tip wall and the suction sidewall, a portion of each tip leakage control channel is curved toward the trailing edge from the inlet to the outlet; and characterised in that the outer surface includes a tip rib extending chordwise along at least a portion of a pressure side of the tip wall between the airfoil leading edge and airfoil trailing edge; and in that the channel inlets are aligned with tip rib along a chordwise path at the pressure side of the tip wall between the airfoil leading edge and airfoil trailing edge.
An arc source system, comprising a cooling body and a holder body adapted to be detachably fastened to said cooling body and for holding a cathode body, the cooling body comprising a lower portion and an upper portion, wherein the system further comprises a membrane which is arranged between the holder body and the lower portion of said cooling body; and in that said lower portion of said cooling body is provided with at least one cooling fluid channel, and wherein said holder body is detachably fastened to said cooling body by at least two fastening devices, characterized in that said fastening devices further are arranged to engage said membrane, wherein said holder body is provided with an inner fastening arrangement configured to be coupled with a corresponding outer fastening arrangement on a cathode body. wherein the system further comprises a membrane which is arranged between the holder body and the lower portion of said cooling body; and in that said lower portion of said cooling body is provided with at least one cooling fluid channel, and wherein said holder body is detachably fastened to said cooling body by at least two fastening devices, characterized in that said fastening devices further are arranged to engage said membrane, wherein said holder body is provided with an inner fastening arrangement configured to be coupled with a corresponding outer fastening arrangement on a cathode body.
A radio-frequency, RF, transformer for use in an isolated DC-DC converter, comprising: a substrate having a first surface and a second surface opposing the first surface; a primary winding having a first coil in contact with and defining a first enclosed area on the first surface, a second coil in contact with and defining a second enclosed area on the first surface, and a capacitor disposed between and connected in series with the first and second coils, wherein the first and second enclosed area are disposed side by side and separated from each other, wherein the first coil comprises: a first coil portion disposed in a first plane; a second coil portion disposed in a second plane parallel to and offset from the first plane; and at least one via connecting the first coil portion and the second coil portion to form the first coil; a secondary winding having a third coil and a fourth coil each in contact with the second surface, wherein a capacitive coupling between the first coil and the third coil equals a capacitive coupling between the second coil and the fourth coil. a substrate having a first surface and a second surface opposing the first surface; a primary winding having a first coil in contact with and defining a first enclosed area on the first surface, a second coil in contact with and defining a second enclosed area on the first surface, and a capacitor disposed between and connected in series with the first and second coils, wherein the first and second enclosed area are disposed side by side and separated from each other, wherein the first coil comprises: a first coil portion disposed in a first plane; a second coil portion disposed in a second plane parallel to and offset from the first plane; and at least one via connecting the first coil portion and the second coil portion to form the first coil; a first coil portion disposed in a first plane; a second coil portion disposed in a second plane parallel to and offset from the first plane; and at least one via connecting the first coil portion and the second coil portion to form the first coil; a secondary winding having a third coil and a fourth coil each in contact with the second surface, wherein a capacitive coupling between the first coil and the third coil equals a capacitive coupling between the second coil and the fourth coil.
A laminated glazing comprising a first pane of glazing material having a first major surface and an opposing second major surface, there being an obscuration band on the second major surface extending around a portion of the periphery of the first pane such that the second major surface is not smooth, a first adhesive layer having a thickness of between 6μm and 100μm, and a plastic carrier ply carrying an infra red reflecting coating, wherein the first adhesive layer is between the first pane of glazing material and the plastic carrier ply and the first adhesive layer contacts a portion of the second major surface and a portion of the obscuration band.
A method of estimating the phase offset between a master clock of a server and a slave clock of a client, the server and the client being in communication over a network, the method including the steps of: within a time window of predetermined duration, exchanging timing messages between the server and the client and recording timestamps which are the times of sending and of receipt of those messages according to the master and slave clocks; determining, from those timestamps, a first plurality of timestamp pairs, which are the times of sending and receipt associated with the least delayed timing messages sent from the server to the client in the window; determining, from those timestamps, a second plurality of timestamp pairs, which are the times of sending and receipt associated with the least delayed timing messages sent from the client to the server in the window; generating, from the first and second plurality of timestamp pairs a plurality of composite timing messages, each of which includes one of said first plurality of timestamp pairs and one of said second plurality of timestamp pairs; using said plurality of composite timing messages to estimate the phase offset between the master clock and the slave clock. within a time window of predetermined duration, exchanging timing messages between the server and the client and recording timestamps which are the times of sending and of receipt of those messages according to the master and slave clocks; determining, from those timestamps, a first plurality of timestamp pairs, which are the times of sending and receipt associated with the least delayed timing messages sent from the server to the client in the window; determining, from those timestamps, a second plurality of timestamp pairs, which are the times of sending and receipt associated with the least delayed timing messages sent from the client to the server in the window; generating, from the first and second plurality of timestamp pairs a plurality of composite timing messages, each of which includes one of said first plurality of timestamp pairs and one of said second plurality of timestamp pairs; using said plurality of composite timing messages to estimate the phase offset between the master clock and the slave clock.
A compound having formula: or any hydrate, solvate, polymorph, or pharmaceutically acceptable salt thereof, wherein: R 1 is selected from the group consisting of optionally substituted phenyl, optionally substituted heteroaryl, and optionally substituted C 3-6 cyclic alkyl; R 2 is selected from the group consisting of fluorine, optionally substituted phenyl, and optionally substituted heteroaryl; R 3 is selected from the group consisting of CO 2 R 4d, and R 4d is selected from the group consisting of hydrogen, optionally substituted C 1-6 linear alkyl, and optionally substituted C 3-6 branched alkyl; R 5 is selected from the group consisting of hydrogen, optionally substituted C 1-6 linear alkyl, and optionally substituted C 3-6 branched alkyl; R 6 is selected from the group consisting of hydrogen, optionally substituted C 1-6 linear alkyl, and optionally substituted C 3-6 branched alkyl; R 7 is selected from the group consisting of hydrogen, optionally substituted C 1-6 linear alkyl, and optionally substituted C 3-6 branched alkyl; L 2 is selected from a group consisting of (CH 2) m, and wherein "**" indicates the point of attachment for R 2; and m is 0. R 1 is selected from the group consisting of optionally substituted phenyl, optionally substituted heteroaryl, and optionally substituted C 3-6 cyclic alkyl; R 2 is selected from the group consisting of fluorine, optionally substituted phenyl, and optionally substituted heteroaryl; R 3 is selected from the group consisting of CO 2 R 4d, and R 4d is selected from the group consisting of hydrogen, optionally substituted C 1-6 linear alkyl, and optionally substituted C 3-6 branched alkyl; R 5 is selected from the group consisting of hydrogen, optionally substituted C 1-6 linear alkyl, and optionally substituted C 3-6 branched alkyl; R 6 is selected from the group consisting of hydrogen, optionally substituted C 1-6 linear alkyl, and optionally substituted C 3-6 branched alkyl; R 7 is selected from the group consisting of hydrogen, optionally substituted C 1-6 linear alkyl, and optionally substituted C 3-6 branched alkyl; L 2 is selected from a group consisting of (CH 2) m, and wherein "**" indicates the point of attachment for R 2; and m is 0.
A dry slag rotary atomising granulator comprising a rotatable disk mounted on a support for rotation about an axis of rotation, wherein the granulator further comprises a cooling system for supplying a coolant to the disk; wherein the disk comprises a first surface to receive slag and a second surface remote from the slag receiving first surface for receiving coolant; wherein the disk comprises a metal; and wherein the disk further comprises terracing on the first surface; and a layer of solidified slag formed on the first surface.
A method for brake health monitoring, comprising: sending, by a brake control unit,BCU, a brake command signal to initiate a braking maneuver; receiving, by the BCU, a first wheel speed signal corresponding to a speed of a first wheel during the braking maneuver; the method characterized by receiving, by the BCU, a second wheel speed signal corresponding to a speed of a second wheel during the braking maneuver; and detecting (306,308,310), by the BCU, that the speed of the first wheel is greater than the speed of the second wheel by greater than a predetermined threshold; wherein the BCU is configured to output a health status indicating a failure in a brake control component associated with the first wheel based upon detection of the speed of the first wheel being greater than the speed of the second wheel by greater than the predetermined threshold. sending, by a brake control unit,BCU, a brake command signal to initiate a braking maneuver; receiving, by the BCU, a first wheel speed signal corresponding to a speed of a first wheel during the braking maneuver; the method characterized by receiving, by the BCU, a second wheel speed signal corresponding to a speed of a second wheel during the braking maneuver; and detecting (306,308,310), by the BCU, that the speed of the first wheel is greater than the speed of the second wheel by greater than a predetermined threshold; wherein the BCU is configured to output a health status indicating a failure in a brake control component associated with the first wheel based upon detection of the speed of the first wheel being greater than the speed of the second wheel by greater than the predetermined threshold.
A method of making an adhesive article, the method comprising: providing a backing having first and second opposed major surfaces, wherein a first silicone release layer is disposed on the first major surface, wherein a second silicone release layer is disposed on the second major surface, and wherein the second silicone release layer further comprises a compound represented by the formula: wherein R 1 represents a hydrocarbyl group having from 2 to 40 carbon atoms; R f represents a perfluorinated group having from 3 to 5 carbon atoms; X 1 represents -NH- or a covalent bond; and an amount of organic solvent sufficient to dissolve at least a portion of the compound in the second silicone release layer; disposing an adhesive layer onto the first silicone release layer; and exposing at least the adhesive layer to electron beam radiation within a process chamber thereby providing a crosslinked adhesive layer, wherein the process chamber contains oxygen, wherein the second silicone release layer is exposed to the oxygen during crosslinking of the adhesive layer. providing a backing having first and second opposed major surfaces, wherein a first silicone release layer is disposed on the first major surface, wherein a second silicone release layer is disposed on the second major surface, and wherein the second silicone release layer further comprises a compound represented by the formula: wherein R 1 represents a hydrocarbyl group having from 2 to 40 carbon atoms; R f represents a perfluorinated group having from 3 to 5 carbon atoms; X 1 represents -NH- or a covalent bond; and an amount of organic solvent sufficient to dissolve at least a portion of the compound in the second silicone release layer; R 1 represents a hydrocarbyl group having from 2 to 40 carbon atoms; R f represents a perfluorinated group having from 3 to 5 carbon atoms; X 1 represents -NH- or a covalent bond; and an amount of organic solvent sufficient to dissolve at least a portion of the compound in the second silicone release layer; disposing an adhesive layer onto the first silicone release layer; and exposing at least the adhesive layer to electron beam radiation within a process chamber thereby providing a crosslinked adhesive layer, wherein the process chamber contains oxygen, wherein the second silicone release layer is exposed to the oxygen during crosslinking of the adhesive layer.
Thermal machine, in particular a gas turbine, comprising a hot gas duct for transferring a hot gas stream which is delimited by a wall (21, 21') which is surrounded on the outside by a cooling duct (20, 20') in which a cooling medium, in particular cooling air, can be conducted along the external face of the wall (21, 21') from an inlet of the cooling duct (20, 20') to an outlet counter to the direction of flow of the hot gas, wherein the cooling duct (20, 20') is formed by the wall (21, 21') of the hot gas duct and by a cooling jacket (19, 19') which is arranged on the outside at a distance from the wall (21, 21'), and wherein a cooling baffle plate (28, 28') is provided at the inlet of the cooling duct (20, 20'), cooling baffle plate (28, 28') includes, in succession in the direction counter to the stream of hot gas starting from an inflow-side edge, an end region which runs parallel to the wall (21, 21') and in which a plurality of cooling baffle holes are provided, distributed over the surface cooling medium being able to enter the cooling duct (20, 20') through said cooling baffle holes perpendicularly with respect to the wall (21, 21') of the hot gas duct and being able to impinge on the wall (21, 21') of the hot gas duct, a junction region which is bent outward in an S shape and in which inlets, through which the cooling medium can flow into the cooling duct (20, 20') parallel to the wall (21, 21'), are provided, and a connecting region which runs parallel to the wall (21, 21'), Characterized in that attachment holes are provided in the connecting region, by means of which attachment holes the cooling baffle plate (28, 28') is attached using spacer elements together with the outer cooling jacket in such a way that a continuous junction is implemented between the cooling baffle plate (28, 28') and the outer cooling jacket, and in that, in order to reduce a transverse flow of the cooling medium in the cooling duct (20, 20'), the inflow-side edge of the cooling baffle plate (28, 28') abuts the wall (21, 21') of the hot gas duct in a seal-forming fashion.
An agent comprising: (i) a targeting moiety that is capable of targeting to solid cancer tumour cells wherein the targeting moiety is an antibody or antigen binding fragment thereof; (ii) a peptide linker comprising a protease cleavage site; and (iii) a T cell antigen wherein the T cell antigen is a viral-derived peptide capable of binding to a MHC Class I molecule and/or MHC Class II molecule; wherein the T cell antigen can be released from the targeting moiety by cleavage of the cleavage site in the linker that is cleavable by a protease selectively in the vicinity of the solid cancer tumour cells; wherein selective cleavage of the protease cleavage site enables release of the T cell antigen in the vicinity of, and outside of, the solid cancer tumour cells, and wherein the agent is for preventing or treating a solid cancer tumour. (i) a targeting moiety that is capable of targeting to solid cancer tumour cells wherein the targeting moiety is an antibody or antigen binding fragment thereof; (ii) a peptide linker comprising a protease cleavage site; and (iii) a T cell antigen wherein the T cell antigen is a viral-derived peptide capable of binding to a MHC Class I molecule and/or MHC Class II molecule;
Expansion anchor - with an expansion sleeve for anchoring to a wall of a drill hole and - with an anchor bolt, which runs through the expansion sleeve, - in which the anchor bolt has an expansion area for the expansion sleeve to spread open, characterised in that the anchor bolt has a cutting thread for cutting into the wall of the drill hole. - with an expansion sleeve for anchoring to a wall of a drill hole and - with an anchor bolt, which runs through the expansion sleeve, - in which the anchor bolt has an expansion area for the expansion sleeve to spread open,
A blood analyzer comprising: a specimen preparation unit comprising a reaction tank, the specimen preparation unit configured to prepare a measurement specimen by mixing in the reaction tank a hemolytic agent that hemolyzes red blood cells, a staining dye that dyes nucleic acids, and a blood specimen; a detector configured to detect intensity of side scattered light and intensity of fluorescence generated with application of light from the measurement specimen prepared by the specimen preparation unit; and an analysis unit configured to discriminate white blood cells from giant platelets based on the intensity of side scattered light and the intensity of fluorescence detected by the detector, and to count the white blood cells, characterized in that the detector is configured to further detect intensity of forward scattered light generated with application of light from the measurement specimen prepared by the specimen preparation unit, and the analysis unit is configured to execute first discrimination processing of discriminating a group of white blood cells from another particle group based on the intensity of forward scattered light and the intensity of fluorescence detected by the detector, and, to execute second discrimination processing of discriminating white blood cells from giant platelets based on the intensity of side scattered light and the intensity of fluorescence when a result of the first discrimination processing meets a predetermined condition. a specimen preparation unit comprising a reaction tank, the specimen preparation unit configured to prepare a measurement specimen by mixing in the reaction tank a hemolytic agent that hemolyzes red blood cells, a staining dye that dyes nucleic acids, and a blood specimen; a detector configured to detect intensity of side scattered light and intensity of fluorescence generated with application of light from the measurement specimen prepared by the specimen preparation unit; and an analysis unit configured to discriminate white blood cells from giant platelets based on the intensity of side scattered light and the intensity of fluorescence detected by the detector, and to count the white blood cells, characterized in that the detector is configured to further detect intensity of forward scattered light generated with application of light from the measurement specimen prepared by the specimen preparation unit, and the analysis unit is configured to execute first discrimination processing of discriminating a group of white blood cells from another particle group based on the intensity of forward scattered light and the intensity of fluorescence detected by the detector, and, to execute second discrimination processing of discriminating white blood cells from giant platelets based on the intensity of side scattered light and the intensity of fluorescence when a result of the first discrimination processing meets a predetermined condition.