A refrigerator, comprising: a storage compartment; a door opening or closing the storage compartment, a vacuum sealing device is disposed on the door, and the vacuum sealing device comprises: an upper support and a lower support opposite to each other, opening cavities are formed on mutually-opposed surfaces of the upper support and/or the lower support; when the upper support and the lower support are butt-joined, the opening cavities sealingly form a vacuumization region by sealing portions; the lower support is detachably mounted to the door; a driving device configured to drive the upper support close to or away from the lower support; a vacuumization assembly in communication with the vacuumization region through a pipe to perform vacuumization or depressurization for the vacuumization region; characterized in that a mounting hole communicating inside with outside is formed on the door, the lower support and an insulation door are disposed in the mounting hole, and the insulation door is at an inner side of the door; the lower support and the insulation door are formed of a first housing and a second housing with opening cavities and an insulation piece disposed between the first housing and the second housing; the first housing is snap-fitted with the second housing, the first housing is provided with an extension arm along a direction away from the second housing, and the lower support is formed on the extension arm. a storage compartment; a door opening or closing the storage compartment, a vacuum sealing device is disposed on the door, and the vacuum sealing device comprises: an upper support and a lower support opposite to each other, opening cavities are formed on mutually-opposed surfaces of the upper support and/or the lower support; when the upper support and the lower support are butt-joined, the opening cavities sealingly form a vacuumization region by sealing portions; the lower support is detachably mounted to the door; a driving device configured to drive the upper support close to or away from the lower support; a vacuumization assembly in communication with the vacuumization region through a pipe to perform vacuumization or depressurization for the vacuumization region; characterized in that a mounting hole communicating inside with outside is formed on the door, the lower support and an insulation door are disposed in the mounting hole, and the insulation door is at an inner side of the door; the lower support and the insulation door are formed of a first housing and a second housing with opening cavities and an insulation piece disposed between the first housing and the second housing; the first housing is snap-fitted with the second housing, the first housing is provided with an extension arm along a direction away from the second housing, and the lower support is formed on the extension arm. an upper support and a lower support opposite to each other, opening cavities are formed on mutually-opposed surfaces of the upper support and/or the lower support; when the upper support and the lower support are butt-joined, the opening cavities sealingly form a vacuumization region by sealing portions; the lower support is detachably mounted to the door; a driving device configured to drive the upper support close to or away from the lower support; a vacuumization assembly in communication with the vacuumization region through a pipe to perform vacuumization or depressurization for the vacuumization region; characterized in that a mounting hole communicating inside with outside is formed on the door, the lower support and an insulation door are disposed in the mounting hole, and the insulation door is at an inner side of the door; the lower support and the insulation door are formed of a first housing and a second housing with opening cavities and an insulation piece disposed between the first housing and the second housing; the first housing is snap-fitted with the second housing, the first housing is provided with an extension arm along a direction away from the second housing, and the lower support is formed on the extension arm.