A compound of Formula II: wherein W represents -N(R 1 R 2) where R 1 and R 2 are not both hydrogen and where they may together form a 5, 6 or 7 membered ring structure, -NHN(R 1 R 2), -NHR 3 N(R 1 R 2), -NHR 3 OR 2, - N(R 3)R 3 OR 2, -N(R 1)R 3 OR 3 OR 3, -OR 3 NR 1 R 2, -OR 3 or W represents piperidyl, piperazinyl, morpholinyl, thiomorpholinyl or diazepanyl each of which may be optionally substituted by C 1 to C 4 alkyl, C 2 to C 4 alkenyl, -N N(R 1 R 2), -N OR 1, -N OR 3 OH, - NR 1 R 2, -R 3 NR 1 R 2, -R 3 OR 1, -OR 1, -N(R 1 R 2) or -NH-; R 1 and R 2 are the same or different and are selected from hydrogen, C 1 to C 4 alkyl or C 2 to C 4 alkenyl; R 3 is a C 1 to C 4 alkyl or C 2 to C 4 alkenyl group or chain; Z is the same or different and represents N or CH; Z' is the same or different and represents N or C; X represents CH, N or NH, where ---- is a double bond when X is CH or N and a single bond when X is NH; X' represents N or NH, wherein when X is CH or N X' is NH and wherein X and X' are different and further where is a double bond when X' is N and a single bond when X' is NH; Q represents H, alkoxyl, -NR 1 R 2, F or Cl; Q 1 is absent when Z' is N and when Z' is C it represents H, alkoxyl, -NR 1 R 2, F or Cl; A represents a five to ten membered single or multiple ring structure with heterocyclic N or O located at the ortho position, said ring including optional double bonds, other heteroatoms and/or substitutions by chloro, fluoro, C 1 to C 4 fluoroalkyl, C 1 to C 4 alkyl, C 2 to C 4 alkenyl, C 1 to C 4 alkoxy, C 1 to C 4 alkoxyalkyl, C 1 to C 4 alkylamino, C 2 to C 4 di-alkylamino or C 1 to C 4 aminoalkyl and pharmaceutically acceptable salts, hydrates or solvates thereof; with the proviso that the compound or pharmaceutically acceptable salt, hydrate or solvate thereof is not: wherein W represents -N(R 1 R 2) where R 1 and R 2 are not both hydrogen and where they may together form a 5, 6 or 7 membered ring structure, -NHN(R 1 R 2), -NHR 3 N(R 1 R 2), -NHR 3 OR 2, - N(R 3)R 3 OR 2, -N(R 1)R 3 OR 3 OR 3, -OR 3 NR 1 R 2, -OR 3 or W represents piperidyl, piperazinyl, morpholinyl, thiomorpholinyl or diazepanyl each of which may be optionally substituted by C 1 to C 4 alkyl, C 2 to C 4 alkenyl, -N N(R 1 R 2), -N OR 1, -N OR 3 OH, - NR 1 R 2, -R 3 NR 1 R 2, -R 3 OR 1, -OR 1, -N(R 1 R 2) or -NH-; R 1 and R 2 are the same or different and are selected from hydrogen, C 1 to C 4 alkyl or C 2 to C 4 alkenyl; R 3 is a C 1 to C 4 alkyl or C 2 to C 4 alkenyl group or chain; Z is the same or different and represents N or CH; Z' is the same or different and represents N or C; X represents CH, N or NH, where ---- is a double bond when X is CH or N and a single bond when X is NH; X' represents N or NH, wherein when X is CH or N X' is NH and wherein X and X' are different and further where is a double bond when X' is N and a single bond when X' is NH; Q represents H, alkoxyl, -NR 1 R 2, F or Cl; Q 1 is absent when Z' is N and when Z' is C it represents H, alkoxyl, -NR 1 R 2, F or Cl; A represents a five to ten membered single or multiple ring structure with heterocyclic N or O located at the ortho position, said ring including optional double bonds, other heteroatoms and/or substitutions by chloro, fluoro, C 1 to C 4 fluoroalkyl, C 1 to C 4 alkyl, C 2 to C 4 alkenyl, C 1 to C 4 alkoxy, C 1 to C 4 alkoxyalkyl, C 1 to C 4 alkylamino, C 2 to C 4 di-alkylamino or C 1 to C 4 aminoalkyl