mhurhangee/ep-ind-claims huggingface dataset:
A compound comprising a modified single-stranded oligonucleotide, wherein said modified oligonucleotide consists of 20 linked nucleosides having a nucleobase sequence consisting of SEQ ID NO: 26, wherein the modified oligonucleotide comprises: a gap segment consisting of ten linked deoxynucleosides; a 5' wing segment consisting of five linked nucleosides; a 3' wing segment consisting of five linked nucleosides; wherein the gap segment is positioned between the 5' wing segment and the 3' wing segment, wherein each nucleoside of each wing segment comprises a 2'-O-methoxyethyl modified sugar, wherein each internucleoside linkage of said modified oligonucleotide is a phosphorothioate linkage, and wherein each cytosine residue of said modified oligonucleotide is a 5-methylcytosine. a gap segment consisting of ten linked deoxynucleosides; a 5' wing segment consisting of five linked nucleosides; a 3' wing segment consisting of five linked nucleosides; wherein the gap segment is positioned between the 5' wing segment and the 3' wing segment, wherein each nucleoside of each wing segment comprises a 2'-O-methoxyethyl modified sugar, wherein each internucleoside linkage of said modified oligonucleotide is a phosphorothioate linkage, and wherein each cytosine residue of said modified oligonucleotide is a 5-methylcytosine.
Method of hydrogenation and calcination of CaCO 3 in a thermally insulated vessel by reacting it with H 2, to produce CaO and a syngas containing at least H 2, CO, H 2 O and CO 2, characterised by a sequence of at least the following consecutive steps carried out at least twice: i) a step of combustion of a fuel to heat up a bed of solids containing at least CaO and CaCO 3 to a maximum heating temperature between 700-1100oC, at a pressure being essentially the equilibrium partial pressure of pure CO 2 on CaO at the maximum heating temperature; ii) a step of reacting with H 2 the heated bed of solids containing at least CaO and CaCO 3, while allowing their adiabatic cooling by 50 to 250oC; iii) a step of replenishing or regenerating the content of CaCO 3 in the solids resulting from step ii). i) a step of combustion of a fuel to heat up a bed of solids containing at least CaO and CaCO 3 to a maximum heating temperature between 700-1100oC, at a pressure being essentially the equilibrium partial pressure of pure CO 2 on CaO at the maximum heating temperature; ii) a step of reacting with H 2 the heated bed of solids containing at least CaO and CaCO 3, while allowing their adiabatic cooling by 50 to 250oC; iii) a step of replenishing or regenerating the content of CaCO 3 in the solids resulting from step ii).
A method, performed by a base station, for configuring uplink sounding signal transmissions by mobile terminals in a wireless communication network, the method comprising: determining multiple different sets of configuration parameters for the uplink sounding signal transmissions for a given mobile terminal of said mobile terminals, each of the multiple different sets of configuration parameters comprising frequency-domain and time-domain parameters, where the frequency-domain parameters comprise a first set of configuration parameters causing the mobile terminal to generate a first one of a sounding reference signal and a second set of configuration parameters causing the mobile terminal to generate a second one of sounding reference signal, where the time-domain parameters comprises a time offset, in number of subframes, of the sounding reference signal, position of the sounding reference signal within the subframe, and/or the period, in number of subframes, of the sounding reference signal; and transmitting the multiple different sets of configuration parameters to the mobile terminal, and receiving, from the mobile terminal, the sounding signals generated by the mobile terminal. determining multiple different sets of configuration parameters for the uplink sounding signal transmissions for a given mobile terminal of said mobile terminals, each of the multiple different sets of configuration parameters comprising frequency-domain and time-domain parameters, where the frequency-domain parameters comprise a first set of configuration parameters causing the mobile terminal to generate a first one of a sounding reference signal and a second set of configuration parameters causing the mobile terminal to generate a second one of sounding reference signal, where the time-domain parameters comprises a time offset, in number of subframes, of the sounding reference signal, position of the sounding reference signal within the subframe, and/or the period, in number of subframes, of the sounding reference signal; and transmitting the multiple different sets of configuration parameters to the mobile terminal, and receiving, from the mobile terminal, the sounding signals generated by the mobile terminal.
A pacemaker lead for cerclage pacing, the pacemaker lead comprising: a lead fixing part including a fixing tip whose diameter becomes gradually smaller toward an end of a distal part thereof, being configured to pierce into a heart muscle or interventricular septum, a plurality of bipolar electrodes that are formed to come into close contact with a heart muscle, in an outer circumference of the lead fixing part, and a guide wire insertion through hole through which a guide wire can be inserted thereinto; a lead body part configured to be extended to the lead fixing part, having a stylet insertion through hole formed therein, and a body fixing part in a bent form so as to be fixed to an inner wall of a coronary sinus; and a stylet inserted or insertable into the stylet insertion through hole, enabling the pacemaker lead for cerclage pacing to be easily moved within the body of a patient. a lead fixing part including a fixing tip whose diameter becomes gradually smaller toward an end of a distal part thereof, being configured to pierce into a heart muscle or interventricular septum, a plurality of bipolar electrodes that are formed to come into close contact with a heart muscle, in an outer circumference of the lead fixing part, and a guide wire insertion through hole through which a guide wire can be inserted thereinto; a lead body part configured to be extended to the lead fixing part, having a stylet insertion through hole formed therein, and a body fixing part in a bent form so as to be fixed to an inner wall of a coronary sinus; and a stylet inserted or insertable into the stylet insertion through hole, enabling the pacemaker lead for cerclage pacing to be easily moved within the body of a patient.
A holding fixture for holding at least one cable, in particular a fibre optic cable, along a longitudinal direction of the cable, the holding fixture comprising an affixing member for holding the cable, the affixing member being shaped with two laterally opposing side supports (3, 4), which define between them a holding channel for at least sectionwise receiving the cable, the holding channel extending in the longitudinal direction, and a clamping member, the clamping member being adapted to be mounted on the affixing member and, in a mounted state, to be moved from a pre-holding to a holding position, characterised in that the affixing member comprises at least one indicator element (77, 78), which, in the pre-holding position, is at least sectionwise laterally shielded by the clamping member and, in the holding position, is arranged in an indication position for indicating that the clamping member is arranged in the holding position.
A method performed by a core network node for a wireless communication network, the method comprising: receiving a request message via an interface with a configuring node associated with a wired communication network, the request message comprising a request for information related to a topology of the wireless communication network; and transmitting an information message via the interface with the configuring node, the information message comprising information related to the topology of the wireless communication network; and receiving a configuration message via the interface with the configuring node, the configuration message comprising settings for a plurality of paths between a first node coupled to the wired communication network and a second node coupled to the wireless communication network, the plurality of paths carrying a plurality of data streams between the first and second nodes, the plurality of data streams comprising at least one redundant data stream; and configuring the plurality of paths within the wireless communication network according to the settings. receiving a request message via an interface with a configuring node associated with a wired communication network, the request message comprising a request for information related to a topology of the wireless communication network; and transmitting an information message via the interface with the configuring node, the information message comprising information related to the topology of the wireless communication network; and receiving a configuration message via the interface with the configuring node, the configuration message comprising settings for a plurality of paths between a first node coupled to the wired communication network and a second node coupled to the wireless communication network, the plurality of paths carrying a plurality of data streams between the first and second nodes, the plurality of data streams comprising at least one redundant data stream; and configuring the plurality of paths within the wireless communication network according to the settings.
Hyperbranched polymer comprising of a) a hyperbranched polycondensate with hydroxyl and/or amino end groups condensed to b) one or more linkers connected to c1) one or more polyethylene glycol monomethyl ethers and c2) one or more poly(C 2 -C 3)alkylene glycol mono-(C 8 -C 22)-alkyl ethers, wherein the weight ratio of components c1): c2) is from 9: 1 to 1: 9. a) a hyperbranched polycondensate with hydroxyl and/or amino end groups condensed to b) one or more linkers connected to c1) one or more polyethylene glycol monomethyl ethers and c2) one or more poly(C 2 -C 3)alkylene glycol mono-(C 8 -C 22)-alkyl ethers,
A method of wireless communication performed by a user equipment, UE, comprising: receiving, from a network entity, a positioning reference signal, PRS, configuration indicating a pattern of PRS resources transmitted by at least one network node; and transmitting a proposed measurement gap pattern to a serving network node, the proposed measurement gap pattern being transmitted in a medium access control control element, MAC-CE, the proposed measurement gap pattern enabling the UE to measure at least a subset of PRS resources transmitted by each of the at least one network node, the proposed measurement gap pattern determined based on the pattern of PRS resources. receiving, from a network entity, a positioning reference signal, PRS, configuration indicating a pattern of PRS resources transmitted by at least one network node; and transmitting a proposed measurement gap pattern to a serving network node, the proposed measurement gap pattern being transmitted in a medium access control control element, MAC-CE, the proposed measurement gap pattern enabling the UE to measure at least a subset of PRS resources transmitted by each of the at least one network node, the proposed measurement gap pattern determined based on the pattern of PRS resources.
A compound of -6-{2-{ethyl[4-(2-ethylaminoethyl)benzyl]amino}-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol for use in treating an estrogen receptor positive breast cancer in a subject, wherein the estrogen receptor positive breast cancer is resistant to an estrogen receptor modulator and wherein the compound is administered in an effective amount of about 200 mg/day to about 500 mg/day.
A portable terminal, comprising: a display unit configured to display a user interface, UI; a communication unit; a memory unit; and a control unit configured to: connect, by the communication unit, with a peripheral device; display, on the display unit, a first UI for controlling data; detect a user input via the first UI to transfer data played in the peripheral device; in response to detecting the user input, receive, by the communication unit, meta information of the data played in the peripheral device from the peripheral device, wherein the meta information comprises connection information and an address for requesting the data from a server; store the meta information in the memory unit; display, on the display unit, a second UI including an item of the data played in the peripheral device and an item of a discovered another peripheral device; select, when the item of the data and the item of the another peripheral device are selected via the second UI, the data and the another peripheral device; and transmit, by the communication unit, the meta information to the another peripheral device. a display unit configured to display a user interface, UI; a communication unit; a memory unit; and a control unit configured to: connect, by the communication unit, with a peripheral device; display, on the display unit, a first UI for controlling data; detect a user input via the first UI to transfer data played in the peripheral device; in response to detecting the user input, receive, by the communication unit, meta information of the data played in the peripheral device from the peripheral device, wherein the meta information comprises connection information and an address for requesting the data from a server; store the meta information in the memory unit; display, on the display unit, a second UI including an item of the data played in the peripheral device and an item of a discovered another peripheral device; select, when the item of the data and the item of the another peripheral device are selected via the second UI, the data and the another peripheral device; and transmit, by the communication unit, the meta information to the another peripheral device. connect, by the communication unit, with a peripheral device; display, on the display unit, a first UI for controlling data; detect a user input via the first UI to transfer data played in the peripheral device; in response to detecting the user input, receive, by the communication unit, meta information of the data played in the peripheral device from the peripheral device, wherein the meta information comprises connection information and an address for requesting the data from a server; store the meta information in the memory unit; display, on the display unit, a second UI including an item of the data played in the peripheral device and an item of a discovered another peripheral device; select, when the item of the data and the item of the another peripheral device are selected via the second UI, the data and the another peripheral device; and transmit, by the communication unit, the meta information to the another peripheral device.
An apparatus for processing a food stuff comprising a housing comprising an upper part and a lower part, an elongate cutting tool rotatably mounted in the housing to rotate about a rotational axis, the elongate cutting tool having a radially extending cutting element and an arcuate support element at one end, and an arcuately extending slot formed between the upper face of the lower part and the lower surface of the upper part and extending circumferentially around the housing, wherein the support element of the elongate cutting tool is configured to slide along the slot as the cutting tool is rotated in the housing so that the elongate cutting tool is supported in an axial direction by the housing.
A compound of formula or formula wherein A, B, C and D, which may be the same or different, independent of one another represent -C(R 7 R 8)-, -C(R 9 R 10)-C(R 11 R 12)-, -N(R 13)-, -O- or -S- with the proviso that the total number of ring atoms of the ring comprising ring members A, B, C and D is 7 to 9, R 1 is selected from the group consisting of OH, OR 3, NH 2, NHR 4 and NR 5 R 6 R 2 is a substituted or unsubstituted alkyl group with 1 to 8 carbon atoms or a substituted or unsubstituted alkoxy group with 1 to 8 carbon atoms in which one or more of the hydrogen atoms may be optionally replaced by halogen, R 3 and R 4, independent of each other, represent an alkyl group with 1 to 6 carbon atoms or a substituted or unsubstituted alkylaryl, aryl or heteroaryl group, R 5 and R 6, independent of each other, represent an alkyl group with 1 to 6 carbon atoms or a substituted or unsubstituted aryl or heteroaryl group or form together with the nitrogen atom to which they are attached, a six- or seven membered, substituted or unsubstituted heterocyclic ring, R 7 to R 13, independent of each other, represent hydrogen, hydroxyl, substituted or unsubstituted alkyl groups with 1 to 4 carbon atoms, substituted or unsubstituted alkoxy groups with 1 to 4 carbon atoms and substituted or unsubstituted hydroxyalkyl groups with 1 to 4 carbon atoms or wherein two of R 7 to R 13 located at adjacent atoms, form together a chemical bond or a ring, R 14 represents a substituted or unsubstituted aryl or heteroaryl group, and R 15 and R 16, independent of each other, are hydrogen or a C 1 to C 4 -alkyl group. A, B, C and D, which may be the same or different, independent of one another represent -C(R 7 R 8)-, -C(R 9 R 10)-C(R 11 R 12)-, -N(R 13)-, -O- or -S- with the proviso that the total number of ring atoms of the ring comprising ring members A, B, C and D is 7 to 9, R 1 is selected from the group consisting of OH, OR 3, NH 2, NHR 4 and NR 5 R 6 R 2 is a substituted or unsubstituted alkyl group with 1 to 8 carbon atoms or a substituted or unsubstituted alkoxy group with 1 to 8 carbon atoms in which one or more of the hydrogen atoms may be optionally replaced by halogen, R 3 and R 4, independent of each other, represent an alkyl group with 1 to 6 carbon atoms or a substituted or unsubstituted alkylaryl, aryl or heteroaryl group, R 5 and R 6, independent of each other, represent an alkyl group with 1 to 6 carbon atoms or a substituted or unsubstituted aryl or heteroaryl group or form together with the nitrogen atom to which they are attached, a six- or seven membered, substituted or unsubstituted heterocyclic ring, R 7 to R 13, independent of each other, represent hydrogen, hydroxyl, substituted or unsubstituted alkyl groups with 1 to 4 carbon atoms, substituted or unsubstituted alkoxy groups with 1 to 4 carbon atoms and substituted or unsubstituted hydroxyalkyl groups with 1 to 4 carbon atoms or wherein two of R 7 to R 13 located at adjacent atoms, form together a chemical bond or a ring, R 14 represents a substituted or unsubstituted aryl or heteroaryl group, and R 15 and R 16, independent of each other, are hydrogen or a C 1 to C 4 -alkyl group.
Handsaw with a grip for actuation by an operator and a saw blade fastened to the grip, comprising a device for aligning the handsaw relative to an object to be sawed with a first visible reference point (c 2) and a second visible reference point (b 2), whose linear distance (c 2 -b 2) to each other forms a predetermined angle in relation to a reference direction of the handsaw, which is defined at a transition between the grip and the saw blade by a straight edge of a grip of the handsaw protruding from the saw blade, wherein the edge is designed to abut on a workpiece, wherein the first reference point (c 2) is defined by an end edge of a linear slot formed in the saw blade and the second reference point (b 2) assigned to the first reference point (c 2) is defined by the other, diametrically-opposed end edge of the linear slot which extends along a linear distance (c 2 -b 2) of the first and of a second reference point (b 2), wherein the linear distance (c 2 -b 2) is defined with an angle of 90° to the reference direction; and the saw blade has a substantially pentagonal shape, at whose longest side a row of saw teeth is formed, wherein a free short edge adjacent the grip adjoins a longitudinal edge of the saw blade, said short edge opens into a fastening region between the grip and the saw blade, wherein an angle between the reference direction and the longitudinal extension of the short edge is 45° or 135°.
A cleaning accessory for a vacuum cleaner, comprising: a housing; a rotatable cleaning brush rotatably mounted to the housing, having at least one flexible cleaning element projecting outwards from a side of the housing and the at least one flexible cleaning element is configured to rotate and engage with a surface to be cleaned; and a rotatable cleaning bar rotatably mounted within the housing, and the rotatable cleaning brush is rotatably coupled to the rotatable cleaning bar; wherein at least a portion of the rotatable cleaning brush is seated within a drive mechanism coupled to the rotatable cleaning bar; characterized in that the rotatable cleaning brush and the rotatable cleaning bar are arranged to rotate about a common rotation axis (A-A). a housing; a rotatable cleaning brush rotatably mounted to the housing, having at least one flexible cleaning element projecting outwards from a side of the housing and the at least one flexible cleaning element is configured to rotate and engage with a surface to be cleaned; and a rotatable cleaning bar rotatably mounted within the housing, and the rotatable cleaning brush is rotatably coupled to the rotatable cleaning bar; wherein at least a portion of the rotatable cleaning brush is seated within a drive mechanism coupled to the rotatable cleaning bar; characterized in that the rotatable cleaning brush and the rotatable cleaning bar are arranged to rotate about a common rotation axis (A-A).
Connection device for coupling a pressurised gas container for storage of pressurised gases, especially carbon dioxide, which container is provided with a connection coupling, characterised by - a guide device, which is pivotable about a pivot axis between a first pivoted position and a second pivoted position, the guide device having, at its end remote from the pivot axis, an opening which is configured for insertion of the pressurised gas container to be coupled in an insertion direction running radially with respect to the pivot axis, and - a plug-in nipple which is rigidly arranged on the connection device and which projects into an inner region of the guide device in such a way that its longitudinal axis runs in a radial direction with respect to the pivot axis of the guide device and, in the first pivoted position of the guide device, is located parallel to the insertion direction. - a guide device, which is pivotable about a pivot axis between a first pivoted position and a second pivoted position, the guide device having, at its end remote from the pivot axis, an opening which is configured for insertion of the pressurised gas container to be coupled in an insertion direction running radially with respect to the pivot axis, and - a plug-in nipple which is rigidly arranged on the connection device and which projects into an inner region of the guide device in such a way that its longitudinal axis runs in a radial direction with respect to the pivot axis of the guide device and, in the first pivoted position of the guide device, is located parallel to the insertion direction.