mhurhangee/ep-ind-claims huggingface dataset:
A photomask blank comprising a resist film deposited thereon, said resist film comprising 100 parts by weight of a base resin which is insoluble in an aqueous alkaline solution, but turns to be soluble in an aqueous alkaline developer under the action of an acid, and comprises a recurring unit having an aromatic structure, an acid generator, a basic compound, and 0.1 to 50 parts by weight of a polymer comprising first recurring units having a side chain having a first fluorinated hydrocarbon group bearing a hydroxyl group which contains the carbon atom to which the hydroxyl group is bonded and vicinal carbon atoms bonded thereto, the vicinal carbon atoms having in total at least two fluorine atoms bonded thereto. 100 parts by weight of a base resin which is insoluble in an aqueous alkaline solution, but turns to be soluble in an aqueous alkaline developer under the action of an acid, and comprises a recurring unit having an aromatic structure, an acid generator, a basic compound, and 0.1 to 50 parts by weight of a polymer comprising first recurring units having a side chain having a first fluorinated hydrocarbon group bearing a hydroxyl group which contains the carbon atom to which the hydroxyl group is bonded and vicinal carbon atoms bonded thereto, the vicinal carbon atoms having in total at least two fluorine atoms bonded thereto.
Process for preparing 2-methylbutanal from the secondary streams obtained in the preparation of mixtures of isomeric α,β-unsaturated decenals, characterized in that a) a mixture comprising linear butenes is reacted in the presence of transition metal compounds of group VIII of the Periodic Table of the Elements with carbon monoxide and hydrogen at elevated temperature and elevated pressure to give a pentanal mixture; b) the pentanal mixture obtained in step a) is converted in the presence of basic compounds to a mixture of isomeric α,β-unsaturated decenals; and c) the mixture obtained in step b) is separated into a stream enriched with unconverted 2-methylbutanal and a stream enriched with a mixture of isomeric α,β-unsaturated decenals; with the proviso that the stream which has been separated off in step c) and is enriched with unconverted 2-methylbutanal is reacted with formaldehyde. a) a mixture comprising linear butenes is reacted in the presence of transition metal compounds of group VIII of the Periodic Table of the Elements with carbon monoxide and hydrogen at elevated temperature and elevated pressure to give a pentanal mixture; b) the pentanal mixture obtained in step a) is converted in the presence of basic compounds to a mixture of isomeric α,β-unsaturated decenals; and c) the mixture obtained in step b) is separated into a stream enriched with unconverted 2-methylbutanal and a stream enriched with a mixture of isomeric α,β-unsaturated decenals; with the proviso
An anchor and a suture for securing tissue, the anchor comprising: a proximal collar, a distal collar, and arms extending between the proximal collar and distal collar, wherein the arms are biased to reconfigure such that, upon release of a constraining force, the arms expand so as to advance the collars toward one another; and a mesh surface extending between the proximal and distal collars (14, 16); wherein the suture passes freely through the anchor, and wherein the suture is routed through the proximal and distal collars. a proximal collar, a distal collar, and arms extending between the proximal collar and distal collar, wherein the arms are biased to reconfigure such that, upon release of a constraining force, the arms expand so as to advance the collars toward one another; and a mesh surface extending between the proximal and distal collars (14, 16); wherein the suture passes freely through the anchor, and wherein the suture is routed through the proximal and distal collars.
A flexible member test apparatus comprising: a driver member having a first diameter and a second diameter, the first diameter is not equal to the second diameter; a first driven member coupled by a first flexible member to the driver member through contact of the first flexible member with a first diameter surface; a second driven member coupled by a second flexible member to the driver member through contact of the second flexible member with a second diameter surface; the first driven member rotationally coupled to a magnetic particle clutch first input shaft; the second driven member rotationally coupled to the magnetic particle clutch, second input shaft; and the magnetic particle clutch first input shaft rotated at a speed different than a rotation speed for the magnetic particle clutch second input shaft. a driver member having a first diameter and a second diameter, the first diameter is not equal to the second diameter; a first driven member coupled by a first flexible member to the driver member through contact of the first flexible member with a first diameter surface; a second driven member coupled by a second flexible member to the driver member through contact of the second flexible member with a second diameter surface; the first driven member rotationally coupled to a magnetic particle clutch first input shaft; the second driven member rotationally coupled to the magnetic particle clutch, second input shaft; and the magnetic particle clutch first input shaft rotated at a speed different than a rotation speed for the magnetic particle clutch second input shaft.
Device for packaging a cosmetic product, in particular a solid or paste cosmetic product, comprising a base, an intermediate part intended to carry the cosmetic product, a lid and locking means, the intermediate part being fixedly mounted to the base and the lid being hingedly mounted on the intermediate part such that said lid occupies two positions, a first position, referred to as the closed position of the device, wherein the base and the lid define a substantially closed space between them, said cosmetic product being housed inside the lid, and a second position, referred to as the open position of the device, wherein the lid is retracted into the base, wherein said lid is configured to be locked in the open position - reciprocally in the closed position - by said locking means comprising at least one protrusion of material projecting from the intermediate part.
An assistive rehabilitation system, ARS, comprising a wearable assistive device and an adaptive assistive and/or rehabilitation device, AARD, wherein the wearable assistive device configured to be supported by the AARD, comprising: a main frame configured to secure to a waist or a pelvis of a user; a leg assembly that, in use, extends downward along the legs of the user from ar end of the main frame; and a main controller configured to control an operation of the leg assembly so that the wearable assistive device is not in contact with a ground surface while the wearable assistive device is supported by the AARD. a main frame configured to secure to a waist or a pelvis of a user; a leg assembly that, in use, extends downward along the legs of the user from ar end of the main frame; and a main controller configured to control an operation of the leg assembly so that the wearable assistive device is not in contact with a ground surface while the wearable assistive device is supported by the AARD.
A computer implemented method for selecting a CRISPR complex for targeting and/or cleavage of a candidate target nucleic acid sequence within a cell, comprising the steps of: (a) determining amount, location and nature of mismatch(es) of guide sequence of potential CRISPR complex(es) and the candidate target nucleic acid sequence, (b) determining contribution of each of the amount, location and nature of mismatch(es) to hybridization free energy of binding between the target nucleic acid sequence and the guide sequence of potential CRISPR complex(es) from a training data set, (c) based on the contribution analysis of step (b), predicting cleavage at the location(s) of the mismatch(es) of the target nucleic acid sequence by the potential CRISPR complex(es), and (d) selecting the CRISPR complex from potential CRISPR complex(es) based on whether the prediction of step (c) indicates that it is more likely than not that cleavage will occur at location(s) of mismatch(es) by the CRISPR complex wherein step (b) is performed by defining a thermodynamic model having a set of weights linking effective free energy of hybridization Z to local free energies G; defining a training set of guide RNA/target DNA sequence pairs; inputting known values of local free energies G for each guide RNA/target DNA sequence pair in the training set; calculating a value of effective free energy of hybridization Z for each guide RNA/target DNA sequence pair in the training set; determining the weights using a machine learning algorithm and outputting the weights whereby the weights can be used to estimate the free energy of hybridization for any sequence. (a) determining amount, location and nature of mismatch(es) of guide sequence of potential CRISPR complex(es) and the candidate target nucleic acid sequence, (b) determining contribution of each of the amount, location and nature of mismatch(es) to hybridization free energy of binding between the target nucleic acid sequence and the guide sequence of potential CRISPR complex(es) from a training data set, (c) based on the contribution analysis of step (b), predicting cleavage at the location(s) of the mismatch(es) of the target nucleic acid sequence by the potential CRISPR complex(es), and (d) selecting the CRISPR complex from potential CRISPR complex(es) based on whether the prediction of step (c) indicates that it is more likely than not that cleavage will occur at location(s) of mismatch(es) by the CRISPR complex
A compound of formula or a pharmaceutically acceptable salt thereof: wherein R 1 is -NR 5 R 6, and R 5 and R 6 are each independently selected from C 1 -C 6 alkyl, and wherein the alkyl is unsubstituted or substituted by -NR 7 R 8; wherein R 2 is selected from C 2 -C 6 alkenyl, the alkenyl is unsubstituted or substituted by -NR 7 R 8; wherein at each occurrence R 7 and R 8 are each independently selected from H or C 1 -C 6 alkyl; wherein R 3 is selected from: and wherein R 4 is selected from C 1 -C 6 alkyl. wherein R 1 is -NR 5 R 6, and R 5 and R 6 are each independently selected from C 1 -C 6 alkyl, and wherein the alkyl is unsubstituted or substituted by -NR 7 R 8; wherein R 2 is selected from C 2 -C 6 alkenyl, the alkenyl is unsubstituted or substituted by -NR 7 R 8; wherein at each occurrence R 7 and R 8 are each independently selected from H or C 1 -C 6 alkyl; wherein R 3 is selected from: and wherein R 4 is selected from C 1 -C 6 alkyl.
A thread-forming nut for positive and non-positive and releasable connection to a stud or bolt, more particularly to a cylindrical stud or bolt, a core hole being provided that has load-bearing thread turns, said thread turns being disposed on a peripheral surface of said core hole in its peripheral direction, characterized in that regions of said thread turns, as regarded in the peripheral direction, comprise fully formed thread turns, that between said fully formed regions (7, 8, 9) of said thread turns there are provided free spaces (10, 11, 12) comprising incompletely formed thread turns in terms of height and in that, that said load-bearing thread turns in said core hole lie at their roots on a minor thread diameter (Dn) and at their crests on a major thread diameter, that said thread turns comprise, at least in part, free spaces (10, 11, 12) that widen said core hole from said minor thread diameter towards said major thread diameter (Dn), wherein said free spaces (10, 11, 12) terminate at a distance from said major thread diameter (Dn) on an outer circle diameter (Da).
A load cell for use with a tong assembly, comprising a body; a chamber formed in the body; a strain gauge disposed in the chamber; a first eye for pivotal coupling a first end of the body to the tong assembly; a second eye for pivotal coupling a second end of the body opposite the first end to the tong assembly; and a biasing member disposed around the second eye for biasing the body relative to the tong assembly. a body; a chamber formed in the body; a strain gauge disposed in the chamber; a first eye for pivotal coupling a first end of the body to the tong assembly; a second eye for pivotal coupling a second end of the body opposite the first end to the tong assembly; and a biasing member disposed around the second eye for biasing the body relative to the tong assembly.
A laminate comprising: a metal substrate; an insulating layer laminated on one surface of the metal substrate; and a patterned metal layer laminated on a surface of the insulating layer on a side opposite to a metal substrate side, the metal layer being 300 μm or more in thickness, the insulating layer comprising boron nitride and an inorganic filler other than boron nitride, the insulating layer comprising the boron nitride as boron nitride aggregated particle, the insulating layer comprising a thermosetting compound and a thermosetting agent or a curing catalyst, and the thermosetting compound comprising an epoxy compound, an oxetane compound, an episulfide compound, or a silicone compound. a metal substrate; an insulating layer laminated on one surface of the metal substrate; and a patterned metal layer laminated on a surface of the insulating layer on a side opposite to a metal substrate side, the metal layer being 300 μm or more in thickness, the insulating layer comprising boron nitride and an inorganic filler other than boron nitride, the insulating layer comprising the boron nitride as boron nitride aggregated particle, the insulating layer comprising a thermosetting compound and a thermosetting agent or a curing catalyst, and the thermosetting compound comprising an epoxy compound, an oxetane compound, an episulfide compound, or a silicone compound.
Flavour and/or fragrance compositions, encompassing (i) one or more tetrahydrofuran derivatives of formula wherein R1 represents hydrogen, C1-C3 alkyl or a O-R2 residue, wherein R2 represents a branched or linear C1-C5 alkyl group or a branched or linear C2-C6 alkenyl group, a substituted or unsubstituted cycloalkyl group, a substituted or unsubstituted (C1-C8) alkyl (C3-C7) cycloalkyl group, a substituted or unsubstituted (C2-C8) alkenyl (C3-C7) cycloalkyl group, a substituted or unsubstituted aryl group or a (C1-C8) alkylaryl group, a substituted or unsubstituted (C2-C8) alkenylaryl group, whereby all stereoisomers of compound are included, and (ii) one or more additional flavour or fragrance compounds, on condition that the total amount of tetrahydrofuran derivatives of formula within said composition ranges from 0.00001 to 40 % by weight - calculated on the total flavour or fragrance composition. (i) one or more tetrahydrofuran derivatives of formula wherein R1 represents hydrogen, C1-C3 alkyl or a O-R2 residue, wherein R2 represents a branched or linear C1-C5 alkyl group or a branched or linear C2-C6 alkenyl group, a substituted or unsubstituted cycloalkyl group, a substituted or unsubstituted (C1-C8) alkyl (C3-C7) cycloalkyl group, a substituted or unsubstituted (C2-C8) alkenyl (C3-C7) cycloalkyl group, a substituted or unsubstituted aryl group or a (C1-C8) alkylaryl group, a substituted or unsubstituted (C2-C8) alkenylaryl group, whereby all stereoisomers of compound are included, and wherein R1 represents hydrogen, C1-C3 alkyl or a O-R2 residue, wherein R2 represents a branched or linear C1-C5 alkyl group or a branched or linear C2-C6 alkenyl group, a substituted or unsubstituted cycloalkyl group, a substituted or unsubstituted (C1-C8) alkyl (C3-C7) cycloalkyl group, a substituted or unsubstituted (C2-C8) alkenyl (C3-C7) cycloalkyl group, a substituted or unsubstituted aryl group or a (C1-C8) alkylaryl group, a substituted or unsubstituted (C2-C8) alkenylaryl group, whereby all stereoisomers of compound are included, and (ii) one or more additional flavour or fragrance compounds, on condition that the total amount of tetrahydrofuran derivatives of formula within said composition ranges from 0.00001 to 40 % by weight - calculated on the total flavour or fragrance composition.
Agricultural tool comprising a device for feeding granular material, such as seed, fertilizer or pesticide, comprising: at least two metering devices; a first drive device (201, 201 a, 201 b), which, via a pressurizing air duct, is connected to the metering devices for generation of a pressurizing airflow for pressurization of the metering devices, and a central container, which is arranged to, via respective feed ducts, with the aid of a respective feed airflow, feed the material to the respective metering device; at least two separator units connected to a respective metering device and arranged for separating from the respective feed airflow the material entering the respective feed ducts; characterized by a second drive device for generation of the said feed airflow; and a merging connection (118, 118') for merging at least a part of the said feed airflow with the pressurizing airflow, wherein the said merging connection connects the respective separator unit to the pressurizing air duct for merging an airflow outflowing from the respective separator unit with the respective pressurizing airflow. at least two metering devices; a first drive device (201, 201 a, 201 b), which, via a pressurizing air duct, is connected to the metering devices for generation of a pressurizing airflow for pressurization of the metering devices, and a central container, which is arranged to, via respective feed ducts, with the aid of a respective feed airflow, feed the material to the respective metering device; at least two separator units connected to a respective metering device and arranged for separating from the respective feed airflow the material entering the respective feed ducts; characterized by a second drive device for generation of the said feed airflow; and a merging connection (118, 118') for merging at least a part of the said feed airflow with the pressurizing airflow, wherein the said merging connection connects the respective separator unit to the pressurizing air duct for merging an airflow outflowing from the respective separator unit with the respective pressurizing airflow.
An injector assembly comprising: an injector which has a distal end portion thereof fitted into a mounting member and injects fuel to be supplied to an engine; and a fuel joint which has a connecting pipe portion to which a fuel hose is connected, and is liquid-tightly connected to a proximal portion of the injector, wherein the injector is fixed to the mounting member in a state where the injector is sandwiched between the fuel joint and the mounting member, wherein the injector assembly further comprises a joint pressing member which is fixed by fastening to the mounting member and restricts the displacement of the fuel joint in the direction away from the mounting member; characterized in that an assembling angle positioning mechanism capable of selectively changing an assembling angle between the fuel joint and the joint pressing member is provided between the fuel joint and the joint pressing member, the assembling angle positioning mechanism includes one fitting element and another fitting element which are engageable with each other by male-female fitting engagement, the one fitting element is constituted of a plurality of fitting elements formed on the fuel joint at different circumferential positions, and the other fitting element is constituted of at least one fitting element formed on the joint pressing member. an injector which has a distal end portion thereof fitted into a mounting member and injects fuel to be supplied to an engine; and a fuel joint which has a connecting pipe portion to which a fuel hose is connected, and is liquid-tightly connected to a proximal portion of the injector, wherein the injector is fixed to the mounting member in a state where the injector is sandwiched between the fuel joint and the mounting member, wherein the injector assembly further comprises a joint pressing member which is fixed by fastening to the mounting member and restricts the displacement of the fuel joint in the direction away from the mounting member; characterized in that an assembling angle positioning mechanism capable of selectively changing an assembling angle between the fuel joint and the joint pressing member is provided between the fuel joint and the joint pressing member, the assembling angle positioning mechanism includes one fitting element and another fitting element which are engageable with each other by male-female fitting engagement, the one fitting element is constituted of a plurality of fitting elements formed on the fuel joint at different circumferential positions, and the other fitting element is constituted of at least one fitting element formed on the joint pressing member.
A computer implemented method of generating a reference signal suitable for comparison to one or more cardiac tissue measured signals, the method comprising selecting a clique of unipoles connected in a non-colinear arrangement; converting a weighted combination of selected unipoles and associated bipoles to electric field components (E x, E y) along x catheter axis and y catheter axis forming a catheter reference frame; converting the electric field components (E x, E y) to electrical potential signals V x and V y, wherein x and y are the axes of catheter reference frame; obtaining time derivatives of the V x and V y signals; normalizing the derivatives of the V x and V y signals to generate a single combination signal correlated with an energy magnitude as a direction independent signal; filtering the combination signal to generate a filtered output signal correlated with depolarization activity; and detecting depolarization activity in the filtered output signal. selecting a clique of unipoles connected in a non-colinear arrangement; converting a weighted combination of selected unipoles and associated bipoles to electric field components (E x, E y) along x catheter axis and y catheter axis forming a catheter reference frame; converting the electric field components (E x, E y) to electrical potential signals V x and V y, wherein x and y are the axes of catheter reference frame; obtaining time derivatives of the V x and V y signals; normalizing the derivatives of the V x and V y signals to generate a single combination signal correlated with an energy magnitude as a direction independent signal; filtering the combination signal to generate a filtered output signal correlated with depolarization activity; and detecting depolarization activity in the filtered output signal.