A trampoline support structure to construct a trampoline frame to allow a jumping assembly and an encircled protection mesh to be installed thereon, comprising: a manifold including a longitudinal installation portion and a transverse installation portion that are integrally formed and an installation hole located on the transverse installation portion in an extended direction of the longitudinal installation portion; a first annular tube which is assembled on the manifold and includes a first assembly section inserted into the transverse installation portion, a first connection section extended from the first assembly section for installation of the jumping assembly; a mesh encircled tube which is assembled on the manifold to support the encircled protection mesh; a second annular tube including a second connection section for installation of the jumping assembly; and a support tube coupled on the longitudinal installation portion and butted the ground to form an interval between the jumping assembly and the ground; characterized in that the first annular tube includes an anchor hole located on the first assembly section and opposed the installation hole when the first assembly section is inserted into the transverse installation portion, the mesh encircled tube includes an anchor section inserted into the installation hole and the anchor hole and extended into the longitudinal installation portion and an extended section extended from the anchor section for installation of the encircled protection mesh, and the second annular tube includes a second assembly section extended from the second connection section and inserted into the first assembly section. a manifold including a longitudinal installation portion and a transverse installation portion that are integrally formed and an installation hole located on the transverse installation portion in an extended direction of the longitudinal installation portion; a first annular tube which is assembled on the manifold and includes a first assembly section inserted into the transverse installation portion, a first connection section extended from the first assembly section for installation of the jumping assembly; a mesh encircled tube which is assembled on the manifold to support the encircled protection mesh; a second annular tube including a second connection section for installation of the jumping assembly; and a support tube coupled on the longitudinal installation portion and butted the ground to form an interval between the jumping assembly and the ground; characterized in that the first annular tube includes an anchor hole located on the first assembly section and opposed the installation hole when the first assembly section is inserted into the transverse installation portion, the mesh encircled tube includes an anchor section inserted into the installation hole and the anchor hole and extended into the longitudinal installation portion and an extended section extended from the anchor section for installation of the encircled protection mesh, and the second annular tube includes a second assembly section extended from the second connection section and inserted into the first assembly section.