A medical image processing device comprising: an image acquisition unit adapted to acquire a medical image obtained from an object to be observed by an endoscope; and a region-of-interest extraction section adapted to extract a first region of interest as a region of interest from the medical image; a region-of-interest change section adapted to perform correction processing for correcting the first region of interest (ROIx) to a second region of interest (ROIy); and a user interface adapted to receive an instruction given to the region-of-interest change section by a user wherein a first medical image and a second medical image different from each other are included in the medical image, meaning that the second medical image is acquired after the first medical image, the region-of-interest change section is adapted to perform the correction processing on the region of interest extracted from the first medical image, the region-of-interest extraction section is adapted to extract a region of interest from the second medical image by using region correction information about the correction processing, the region-of-interest change section is adapted to perform the correction processing by changing a region-of-interest extraction condition for extraction of the region of interest, the region-of-interest extraction section is adapted to calculate a first feature quantity from the medical image and to extract a region where the first feature quantity is in a first region extraction range as the region of interest, and the region-of-interest extraction condition is a condition about the first region extraction range. an image acquisition unit adapted to acquire a medical image obtained from an object to be observed by an endoscope; and a region-of-interest extraction section adapted to extract a first region of interest as a region of interest from the medical image; a region-of-interest change section adapted to perform correction processing for correcting the first region of interest (ROIx) to a second region of interest (ROIy); and a user interface adapted to receive an instruction given to the region-of-interest change section by a user wherein a first medical image and a second medical image different from each other are included in the medical image, meaning that the second medical image is acquired after the first medical image, the region-of-interest change section is adapted to perform the correction processing on the region of interest extracted from the first medical image, the region-of-interest extraction section is adapted to extract a region of interest from the second medical image by using region correction information about the correction processing, the region-of-interest change section is adapted to perform the correction processing by changing a region-of-interest extraction condition for extraction of the region of interest, the region-of-interest extraction section is adapted to calculate a first feature quantity from the medical image and to extract a region where the first feature quantity is in a first region extraction range as the region of interest, and the region-of-interest extraction condition is a condition about the first region extraction range.