mhurhangee/ep-ind-claims huggingface dataset:
A method of processing starch comprising liquefying a starch and/or saccharifying a starch liquefact to form a saccharide syrup by adding a Pseudomonas saccharophila amylase variant, wherein the variant comprises a sequence having at least 90% sequence identity to the amino acid sequence of SEQ ID NO: 1, residues 1 to 429 of SEQ ID NO: 1, or SEQ ID NO: 2, wherein the variant has a decreased ratio of exo- to endo-amylase activity compared to the amino acid sequence of SEQ ID NO: 1, residues 1 to 429 of SEQ ID NO: 1, or SEQ ID NO: 2, and wherein the PS4 variant comprises the amino acid substitution Q169R, Q169K, or Q169V at a position corresponding to position 169 of SEQ ID NO: 1 and, optionally; (i) one or more amino acid substitutions at following positions: 7, 8, 32, 38, 49, 62, 63, 64, 67, 72, 73, 74, 75, 76, 104, 106, 107, 110, 112, 116, 119, 122, 123, 124, 125, 126, 128, 130, 137, 138, 140, 142, 143, 144, 148, 149, 150, 151, 154, 156, 163, 164, 168, 182, 183, 192, 195, 196, 200, 202, 208, 213, 220, 222, 225, 226, 227, 232, 233, 234, 236, 237, 239, 253, 255, 257, 260, 264, 267, 269, 271, 276, 282, 285, 295, 297, 300, 302, 305, 308, 312, 323, 324, 325, 341, 358, 367, 379, 390, of SEQ ID NO: 1, 2, 3, 4, 5, or 6; (ii) one or more following amino acid substitutions: A3T, G9A, H13R, 146F, D68E, G69A/E/H/I/K/M/R/T, G70A/E/L/P/Q/S/V, K71M, G100A/S, G1211/P/R, A131T, G134C, A141S, N145S, Y146D/E, G153A/D, G158C/F/I/L/P/Q/V, S161G/H/K/P/R/T/V, G166N, I170E/K/L/M/N, L178N/Q/W, A179E/N/P/R/S, A179S, G184Q, G188A, A199P, G223C/F/H/M/N/Q/W/Y, S229N, W238E/G/K/P/Q/R, G303L, H307D/E/F/G/K/M/P/Q/R/S/W/Y, A309E/I/M/T/V, S334A/H/K/L/M/Q/R/T, and/or H335M of SEQ ID NO: 1, 2, 3, 4, 5, or 6; and/or (iii) one or more amino acid substitutions at positions of 420, 422, and/or 424 of SEQ ID NO: 1. (i) one or more amino acid substitutions at following positions: 7, 8, 32, 38, 49, 62, 63, 64, 67, 72, 73, 74, 75, 76, 104, 106, 107, 110, 112, 116, 119, 122, 123, 124, 125, 126, 128, 130, 137, 138, 140, 142, 143, 144, 148, 149, 150, 151, 154, 156, 163, 164, 168, 182, 183, 192, 195, 196, 200, 202, 208, 213, 220, 222, 225, 226, 227, 232, 233, 234, 236, 237, 239, 253, 255, 257, 260, 264, 267, 269, 271, 276, 282, 285, 295, 297, 300, 302, 305, 308, 312, 323, 324, 325, 341, 358, 367, 379, 390, of SEQ ID NO: 1, 2, 3, 4, 5, or 6; (ii) one or more following amino acid substitutions: A3T, G9A, H13R, 146F, D68E, G69A/E/H/I/K/M/R/T, G70A/E/L/P/Q/S/V, K71M, G100A/S, G1211/P/R, A131T, G134C, A141S, N145S, Y146D/E, G153A/D, G158C/F/I/L/P/Q/V, S161G/H/K/P/R/T/V, G166N, I170E/K/L/M/N, L178N/Q/W, A179E/N/P/R/S, A179S, G184Q, G188A, A199P, G223C/F/H/M/N/Q/W/Y, S229N, W238E/G/K/P/Q/R, G303L, H307D/E/F/G/K/M/P/Q/R/S/W/Y, A309E/I/M/T/V, S334A/H/K/L/M/Q/R/T, and/or H335M of SEQ ID NO: 1, 2, 3, 4, 5, or 6; and/or (iii) one or more amino acid substitutions at positions of 420, 422, and/or 424 of SEQ ID NO: 1.
A compound comprising a NO-releasing moiety, a H 2 S-releasing moiety, and a core, wherein the core comprises in which each of s and t, independently, is 1, 2, 3, or 4; r is 1 or 2; Z is O or NH; each of R 1, R 2, R 3, R 4,R 5, R 6, and R 7, independently, is H, halo, NO 2, N 3, C 1 -C 10 alkyl, OR, OC R, N 2, NH-C R, S R, or N=N-R, in which each R, independently, is H, C 1 -C 10 alkyl, or aryl, and in which each of the NO-releasing moiety and the H 2 S-releasing moiety is covalently bonded to the core.
A steel sheet for soft-nitriding, having: a chemical composition consisting of, on a mass percent basis: C: 0.05% or more to 0.10% or less; Si: 0.5% or less; Mn: 0.7% or more to 1.5% or less; P: 0.05% or less; S: 0.01% or less; Al: 0.01% or more to 0.06% or less; Cr: 0.5% or more to 1.5% or less; V: 0.03% or more to 0.30% or less; and N: 0.005% or less; and optionally Nb: 0.005% or more to 0.025% or less, Cu: 0.05% or less, Ni: 0.05% or less, Mo: 0.05% or less, Co: 0.05% or less, Ti: 0.005% or less, Zr: 0.005% or less, Ca: 0.005% or less, Sn: 0.005% or less, O: 0.005% or less, and B: 0.0005% or less, wherein a ratio of amount of solute V to the V content, amount of solute V/V content, is more than 0.50, and the balance is Fe and incidental impurities, and a complex-phase microstructure containing ferrite as a main phase and pearlite as a second phase. C: 0.05% or more to 0.10% or less; Si: 0.5% or less; Mn: 0.7% or more to 1.5% or less; P: 0.05% or less; S: 0.01% or less; Al: 0.01% or more to 0.06% or less; Cr: 0.5% or more to 1.5% or less; V: 0.03% or more to 0.30% or less; and N: 0.005% or less; Nb: 0.005% or more to 0.025% or less, Cu: 0.05% or less, Ni: 0.05% or less, Mo: 0.05% or less, Co: 0.05% or less, Ti: 0.005% or less, Zr: 0.005% or less, Ca: 0.005% or less, Sn: 0.005% or less, O: 0.005% or less, and B: 0.0005% or less,
An implantable inflatable penile prosthesis cylinder comprising: an outer tube member having a longitudinal axis; an inner tube member contained within the outer tube member, the inner tube member comprising at least one inflatable chamber section, wherein at least a portion of each chamber section is defined by a wall of the inner tube member; and one or more tensile support members within the inner tube member, each tensile support member extending between interior surfaces of the wall; wherein the one or more tensile support members are in tension when the at least one chamber section is in an inflated state. an outer tube member having a longitudinal axis; an inner tube member contained within the outer tube member, the inner tube member comprising at least one inflatable chamber section, wherein at least a portion of each chamber section is defined by a wall of the inner tube member; and one or more tensile support members within the inner tube member, each tensile support member extending between interior surfaces of the wall; wherein the one or more tensile support members are in tension when the at least one chamber section is in an inflated state.
An electric wire comprising: a central conductor made of aluminum or an aluminum alloy; a cover layer made of copper and covering the central conductor; and a ferromagnetic layer covering the cover layer and blocking an external magnetic field, characterized in that a thickness of the ferromagnetic layer is in a range from 0.04 μm to 14 μm, a total diameter of the central conductor and the cover layer is in a range from 0.05 mm to 0.4 mm, and a cross-sectional area of the central conductor is in a range from 85% to 95% of a total cross-sectional area of the central conductor and the cover layer, wherein relative magnetic permeability of the ferromagnetic layer is in a range from 5 to 10000, and wherein the electric wire may be used at a frequency approximately in the range from 200 Hz to 30 MHz. a central conductor made of aluminum or an aluminum alloy; a cover layer made of copper and covering the central conductor; and a ferromagnetic layer covering the cover layer and blocking an external magnetic field,
An antenna module, comprising: a feeding branch, a first branch, a second branch, a third branch and a grounding branch; wherein the feeding branch is connected to a feeding point, and the grounding branch is connected to a grounding point; the first branch and the third branch are concave branches; the second branch is a bent branch; the feeding branch, the first branch, the second branch, the third branch and the grounding branch are connected in sequence to form an annular structure with a slot; the slot is located between the feeding branch and the grounding branch; wherein the first branch comprises a first portion, a second portion, and a third portion; the first portion, the second portion and the third portion are connected in sequence, the first portion and the second portion form an L-shaped branch, and the second portion and the third portion form an L-shaped branch; the feeding branch is connected to the first portion, and the third portion is connected to the second branch; wherein the feeding branch comprises a first feeding portion and a second feeding portion, the first feeding portion is connected to the first portion of the first branch, and the first feeding portion is connected to the second feeding portion; the first feeding portion and the second feeding portion form an L-shaped branch; the first feeding portion and the first portion form an L-shaped branch; and characterized in that the first portion and the second feeding portion extend in opposite directions from the first feeding portion. wherein the feeding branch is connected to a feeding point, and the grounding branch is connected to a grounding point; the first branch and the third branch are concave branches; the second branch is a bent branch; the feeding branch, the first branch, the second branch, the third branch and the grounding branch are connected in sequence to form an annular structure with a slot; the slot is located between the feeding branch and the grounding branch; wherein the first branch comprises a first portion, a second portion, and a third portion; the first portion, the second portion and the third portion are connected in sequence, the first portion and the second portion form an L-shaped branch, and the second portion and the third portion form an L-shaped branch; the feeding branch is connected to the first portion, and the third portion is connected to the second branch; wherein the feeding branch comprises a first feeding portion and a second feeding portion, the first feeding portion is connected to the first portion of the first branch, and the first feeding portion is connected to the second feeding portion; the first feeding portion and the second feeding portion form an L-shaped branch; the first feeding portion and the first portion form an L-shaped branch; and characterized in that the first portion and the second feeding portion extend in opposite directions from the first feeding portion.
An isolated monoclonal antibody or antigen binding fragment thereof, comprising a heavy chain variable region comprising a heavy chain complementarity determining region (HCDR)1, a HCDR2, and a HCDR3, and a light chain variable region comprising a light chain complementarity determining region (LCDR)1, a LCDR2, and a L-CDR3, of the amino acid sequences set forth as: (a) SEQ ID NO: 1 and SEQ ID NO: 2, respectively (clone 13); (b) SEQ ID NO: 3 and SEQ ID NO: 4, respectively (clone 22); or (c) SEQ ID NO: 5 and SEQ ID NO: 6, respectively (clone 26); and wherein the monoclonal antibody or antigen binding fragment specifically binds to matrilin-3, and wherein the monoclonal antibody or antigen binding fragment is conjugated to a chondrogenic agent selected from the group consisting of: a growth hormone; an insulin-like growth factor-1; an Indian hedgehog; a bone morphogenetic protein; a C-type natriuretic protein; a Wnt protein; or a steroid, or a fragment thereof that induces chondrogenesis, and wherein: (a) the HCDR1, HCDR2, and HCDR3 comprise the amino acid sequences set forth as residues 26-33, 51-58, and 97-106 of SEQ ID NO: 1, respectively, and the LCDR1, LCDR2, and LCDR3 comprise the amino acid sequence set forth as residues 27-32, 50-52, and 89-97 of SEQ ID NO: 2, respectively; (b) the HCDR1, HCDR2, and HCDR3 comprise the amino acid sequences set forth as residues 26-33, 53-61, and 100-109 of SEQ ID NO: 3, respectively, and the LCDR1, LCDR2, and LCDR3 comprise the amino acid sequence set forth as residues 26-31, 49-51, and 88-97 of SEQ ID NO: 4 respectively; or (c) the HCDR1, HCDR2, and HCDR3 comprise the amino acid sequences set forth as residues 26-33, 51-58, 97-108 of SEQ ID NO: 5, respectively, and the LCDR1, LCDR2, and LCDR3 comprise the amino acid sequence set forth as residues 26-33, 51-53, and 90-100 of SEQ ID NO: 6, respectively. (a) SEQ ID NO: 1 and SEQ ID NO: 2, respectively (clone 13); (b) SEQ ID NO: 3 and SEQ ID NO: 4, respectively (clone 22); or (c) SEQ ID NO: 5 and SEQ ID NO: 6, respectively (clone 26); and (a) the HCDR1, HCDR2, and HCDR3 comprise the amino acid sequences set forth as residues 26-33, 51-58, and 97-106 of SEQ ID NO: 1, respectively, and the LCDR1, LCDR2, and LCDR3 comprise the amino acid sequence set forth as residues 27-32, 50-52, and 89-97 of SEQ ID NO: 2, respectively; (b) the HCDR1, HCDR2, and HCDR3 comprise the amino acid sequences set forth as residues 26-33, 53-61, and 100-109 of SEQ ID NO: 3, respectively, and the LCDR1, LCDR2, and LCDR3 comprise the amino acid sequence set forth as residues 26-31, 49-51, and 88-97 of SEQ ID NO: 4 respectively; or (c) the HCDR1, HCDR2, and HCDR3 comprise the amino acid sequences set forth as residues 26-33, 51-58, 97-108 of SEQ ID NO: 5, respectively, and the LCDR1, LCDR2, and LCDR3 comprise the amino acid sequence set forth as residues 26-33, 51-53, and 90-100 of SEQ ID NO: 6, respectively.
An ophthalmic device, comprising an elastomeric matrix, said elastomeric matrix comprises: poly(vinyl alcohol) (PVOH), at least one plasticizer which is not water, and water, wherein: a mass ratio of said plasticizer to said PVOH is at least 2:1; and a combined mass content of said PVOH and said plasticizer is at least 70 %wt of the total weight of the matrix excluding said water. poly(vinyl alcohol) (PVOH), at least one plasticizer which is not water, and water, wherein: a mass ratio of said plasticizer to said PVOH is at least 2:1; and a combined mass content of said PVOH and said plasticizer is at least 70 %wt of the total weight of the matrix excluding said water. a mass ratio of said plasticizer to said PVOH is at least 2:1; and a combined mass content of said PVOH and said plasticizer is at least 70 %wt of the total weight of the matrix excluding said water.
A biosensor device for detecting the presence of a single molecule of an analyte in a sample comprising: a) an oligomeric or polymeric pore assembly comprising a number of pore-subunit polypeptides sufficient to form a pore, wherein at least one of said pore-subunit polypeptides is a staphylococcal alpha hemolysin polypeptide that comprises at least a first heterologous amino acid covalently linked to at least a first analyte-binding sensing moiety; b) means to detect the electrical current flowing through said pore assembly when said at least a first analyte-binding sensing moiety binds to a single molecule of said analyte; wherein said analyte is a nucleotide, an amino acid, a peptide or a saccharide; and wherein a modulation in electrical current through at least a first pore assembly compared to a current measurement lacking the analyte indicates the presence of the single molecule of the analyte in the sample. a) an oligomeric or polymeric pore assembly comprising a number of pore-subunit polypeptides sufficient to form a pore, wherein at least one of said pore-subunit polypeptides is a staphylococcal alpha hemolysin polypeptide that comprises at least a first heterologous amino acid covalently linked to at least a first analyte-binding sensing moiety; b) means to detect the electrical current flowing through said pore assembly when said at least a first analyte-binding sensing moiety binds to a single molecule of said analyte;
A method for selecting a monovalent ligand of the human CD28 receptor, capable of selectively blocking the CD28/B7 interaction without activating the CD28 receptor, characterized in that it comprises bringing monovalent ligands of the human CD28 receptor into contact with a polypeptide which has the sequence of the human CD28 receptor or a fragment thereof comprising the sequences SEQ ID NO: 2, SEQ ID NO: 3 and SEQ ID NO: 4, and selecting a ligand which recognises an epitope formed by the sequences SEQ ID NO: 2, SEQ ID NO: 3, and SEQ ID NO: 4.
A mobile wireless communications device comprising: a printed circuit board, "PCB" (12, 42, 52, 62); wireless transceiver circuitry carried by said PCB and operating on a plurality of frequency bands; at least one antenna; and a multi-bandpass transmission line (10, 40, 50, 60) coupling said wireless transceiver circuitry to said at least one antenna and comprising an electrically conductive trace on a surface of said PCB defining a transmission line signal path, and an electrically conductive layer on an opposite surface of said PCB and defining a ground plane (16, 46, 56, 66), said electrically conductive layer having at least one set of slot rings (18, 48, 58, 68) therein and defining a plurality of slot ring resonators (19, 49, 59, 69) being electromagnetically coupled to the transmission line signal path and operable at said plurality of frequency bands, wherein each slot ring of a given set of slot rings defines a respective resonant frequency within a given frequency band characterized in that the at least one set of slot rings (18, 48, 58, 68) is of concentric uninterrupted slot rings (18, 48, 58, 68). a printed circuit board, "PCB" (12, 42, 52, 62); wireless transceiver circuitry carried by said PCB and operating on a plurality of frequency bands; at least one antenna; and a multi-bandpass transmission line (10, 40, 50, 60) coupling said wireless transceiver circuitry to said at least one antenna and comprising an electrically conductive trace on a surface of said PCB defining a transmission line signal path, and an electrically conductive layer on an opposite surface of said PCB and defining a ground plane (16, 46, 56, 66), said electrically conductive layer having at least one set of slot rings (18, 48, 58, 68) therein and defining a plurality of slot ring resonators (19, 49, 59, 69) being electromagnetically coupled to the transmission line signal path and operable at said plurality of frequency bands, wherein each slot ring of a given set of slot rings defines a respective resonant frequency within a given frequency band characterized in that the at least one set of slot rings (18, 48, 58, 68) is of concentric uninterrupted slot rings (18, 48, 58, 68). an electrically conductive trace on a surface of said PCB defining a transmission line signal path, and an electrically conductive layer on an opposite surface of said PCB and defining a ground plane (16, 46, 56, 66), said electrically conductive layer having at least one set of slot rings (18, 48, 58, 68) therein and defining a plurality of slot ring resonators (19, 49, 59, 69) being electromagnetically coupled to the transmission line signal path and operable at said plurality of frequency bands, wherein each slot ring of a given set of slot rings defines a respective resonant frequency within a given frequency band characterized in that the at least one set of slot rings (18, 48, 58, 68) is of concentric uninterrupted slot rings (18, 48, 58, 68).
A water-soluble film comprising a polyvinyl alcohol resin, wherein, when a crystallinity index calculated using a diamond prism is Fd1 and a crystallinity index calculated using a germanium prism is Fg1 for FT-IR measurement of a first surface of the water-soluble film by ATR technique, the Fd1 and the Fg1 satisfy formulae below: Fd 1 ≤ 0.65 Fd 1 / Fg 1 < 1 when a crystallinity index calculated using a diamond prism is Fd1 and a crystallinity index calculated using a germanium prism is Fg1 for FT-IR measurement of a first surface of the water-soluble film by ATR technique, the Fd1 and the Fg1 satisfy formulae below: Fd 1 ≤ 0.65 Fd 1 / Fg 1 < 1
A method for use when providing a contextually-aware media object recommendation, the method being performed by a server and comprising: obtaining metadata associated with a media object from a plurality of data sources; extracting from the metadata a plurality of terms associated with the media object; and mapping at least a portion of the plurality of terms to a plurality of buckets; wherein the method is characterized by further comprising: calculating, for each term of the plurality of terms, a probability that the term is associated with the media object; associating the probability to each term, correspondingly; generating a vector of term-weight attributes based on the associating; generating a document containing at least the vector; storing the document in a database; generating a query vector corresponding to at least one of the plurality of buckets; and querying the database by using the query vector. obtaining metadata associated with a media object from a plurality of data sources; extracting from the metadata a plurality of terms associated with the media object; and mapping at least a portion of the plurality of terms to a plurality of buckets; calculating, for each term of the plurality of terms, a probability that the term is associated with the media object; associating the probability to each term, correspondingly; generating a vector of term-weight attributes based on the associating; generating a document containing at least the vector; storing the document in a database; generating a query vector corresponding to at least one of the plurality of buckets; and querying the database by using the query vector.
An exercise apparatus (100, 200, 400, 500) comprising: a first thigh member (102a, 202a, 402a, 502a) and a second thigh member (102b, 202b, 402b, 502b) moving in a first reciprocal motion when the user engages the first and second thigh members (102a, 102b, 202a, 202b, 402a, 402b, 502a, 502b), the first reciprocal motion varying a first distance between the first and second thigh members (102a, 102b, 202a, 202b, 402a, 402b, 502a, 502b); and a chest contact member (101, 201, 401, 501) moving in a second reciprocal motion when a user engages the chest contact member (101, 201, 401, 501), the second reciprocal motion varying a second distance between the chest contact member (101, 201, 401, 501) and the first and second thigh members (102a, 102b, 202a, 202b, 402a, 402b, 502a, 502b), characterized in that the exercise apparatus (100, 200, 400, 500) further comprises an abdominal contact member (110, 210, 410, 510) moving in a third reciprocal motion when the user engages the abdominal contact member (110, 210, 410, 510), the third reciprocal motion varying a third distance between the abdominal contact member (110, 210, 410, 510) and the first and second thigh members (102a, 102b, 202a, 202b, 402a, 402b, 502a, 502b). a first thigh member (102a, 202a, 402a, 502a) and a second thigh member (102b, 202b, 402b, 502b) moving in a first reciprocal motion when the user engages the first and second thigh members (102a, 102b, 202a, 202b, 402a, 402b, 502a, 502b), the first reciprocal motion varying a first distance between the first and second thigh members (102a, 102b, 202a, 202b, 402a, 402b, 502a, 502b); and a chest contact member (101, 201, 401, 501) moving in a second reciprocal motion when a user engages the chest contact member (101, 201, 401, 501), the second reciprocal motion varying a second distance between the chest contact member (101, 201, 401, 501) and the first and second thigh members (102a, 102b, 202a, 202b, 402a, 402b, 502a, 502b), characterized in that the exercise apparatus (100, 200, 400, 500) further comprises an abdominal contact member (110, 210, 410, 510) moving in a third reciprocal motion when the user engages the abdominal contact member (110, 210, 410, 510), the third reciprocal motion varying a third distance between the abdominal contact member (110, 210, 410, 510) and the first and second thigh members (102a, 102b, 202a, 202b, 402a, 402b, 502a, 502b).