mhurhangee/ep-ind-claims huggingface dataset:
A method of analyzing a plasma sample of an organism, the plasma sample including cell-free DNA fragments originating from normal cells and potentially from cells associated with cancer, the method comprising: for each of a plurality of DNA fragments from the plasma sample: receiving one or more sequence reads obtained from a sequencing of the DNA fragment, the one or more sequence reads including both ends of the DNA fragment; aligning the one or more sequence reads to a reference genome to obtain aligned locations for both ends of the DNA fragment; and using the aligned locations to determine a size of the DNA fragment; for each size of a plurality of sizes: determining an amount of a set of the plurality of DNA fragments from the plasma sample corresponding to the size, using the sizes determined from the aligned locations for the set of the plurality of DNA fragments; calculating a first value of a first parameter based on the amounts of DNA fragments at multiple sizes, the first parameter providing a statistical measure of a size profile of DNA fragments in the plasma sample; comparing the first value to a calibration value; and estimating a fractional concentration of tumor DNA in the plasma sample based on the comparison. for each of a plurality of DNA fragments from the plasma sample: receiving one or more sequence reads obtained from a sequencing of the DNA fragment, the one or more sequence reads including both ends of the DNA fragment; aligning the one or more sequence reads to a reference genome to obtain aligned locations for both ends of the DNA fragment; and using the aligned locations to determine a size of the DNA fragment; receiving one or more sequence reads obtained from a sequencing of the DNA fragment, the one or more sequence reads including both ends of the DNA fragment; aligning the one or more sequence reads to a reference genome to obtain aligned locations for both ends of the DNA fragment; and using the aligned locations to determine a size of the DNA fragment; for each size of a plurality of sizes: determining an amount of a set of the plurality of DNA fragments from the plasma sample corresponding to the size, using the sizes determined from the aligned locations for the set of the plurality of DNA fragments; calculating a first value of a first parameter based on the amounts of DNA fragments at multiple sizes, the first parameter providing a statistical measure of a size profile of DNA fragments in the plasma sample; comparing the first value to a calibration value; and estimating a fractional concentration of tumor DNA in the plasma sample based on the comparison.
An information processing apparatus, comprising: display element information acquisition means for acquiring display element information output by the application program during an execution of an application program, and storing the display element information in a storage unit; and program-related image display control means for generating an image including a display element represented by the display element information stored in the storage unit as a program-related image for presenting information relating to the application program, and controlling a display unit to display the generated image during a period in which the application program is not executed, characterized in that: the display element information acquisition means acquires, along with the display element information, information indicating a display time period for displaying the display element represented by the display element information stored in the storage unit; and the program-related image display control means controls a display timing of the display element represented by the display element information by using the information indicating the display time period. display element information acquisition means for acquiring display element information output by the application program during an execution of an application program, and storing the display element information in a storage unit; and program-related image display control means for generating an image including a display element represented by the display element information stored in the storage unit as a program-related image for presenting information relating to the application program, and controlling a display unit to display the generated image during a period in which the application program is not executed, characterized in that: the display element information acquisition means acquires, along with the display element information, information indicating a display time period for displaying the display element represented by the display element information stored in the storage unit; and the program-related image display control means controls a display timing of the display element represented by the display element information by using the information indicating the display time period. the display element information acquisition means acquires, along with the display element information, information indicating a display time period for displaying the display element represented by the display element information stored in the storage unit; and the program-related image display control means controls a display timing of the display element represented by the display element information by using the information indicating the display time period.
An impact tool comprising: an electric motor including a permanent magnet and a coil; an impact mechanism configured to perform an impact operation that generates impacting force by receiving motive power from the electric motor; an acquisition unit configured to acquire at least one of: a value of a torque current to be supplied to the coil; or a value of an excitation current to be supplied to the coil, the excitation current generating, in the coil, a magnetic flux causing a variation in the permanent magnet's magnetic flux; and a behavior decision unit configured to make, based on at least one of a torque current acquisition value or an excitation current acquisition value, a decision about behavior of the impact mechanism, the torque current acquisition value being the value of the torque current acquired by the acquisition unit, the excitation current acquisition value being the value of the excitation current acquired by the acquisition unit. an electric motor including a permanent magnet and a coil; an impact mechanism configured to perform an impact operation that generates impacting force by receiving motive power from the electric motor; an acquisition unit configured to acquire at least one of: a value of a torque current to be supplied to the coil; or a value of an excitation current to be supplied to the coil, the excitation current generating, in the coil, a magnetic flux causing a variation in the permanent magnet's magnetic flux; and a behavior decision unit configured to make, based on at least one of a torque current acquisition value or an excitation current acquisition value, a decision about behavior of the impact mechanism, the torque current acquisition value being the value of the torque current acquired by the acquisition unit, the excitation current acquisition value being the value of the excitation current acquired by the acquisition unit.
Towed agricultural machine including a carrier frame fitted with conditioning tools and able to be connected to the three-point hitch of a tractor by means of a coupling frame, the carrier frame resting on the ground at least during transport by means of wheels and a load transfer system extending between the carrier frame and the coupling frame to exert a force on the coupling frame in at least one so-called intermediate configuration in which the majority of the conditioning tools are not in contact with the soil and are positioned behind the wheels, characterised in that it includes a device that can isolate the hydraulic circuit of the load transfer system in the so-called intermediate configuration.
Panel, in particular a worktop, comprising a carrier plate which has an upper and a lower main surface, a front surface which extends from the upper main surface to the lower main surface, a support edge which is formed separately from the carrier plate and is arranged on the front surface of the carrier plate, and a decorative layer which is formed separately from the carrier plate and the support edge and extends from the upper surface of the carrier plate over the front surface of the carrier plate and the support edge to the lower surface of the support plate, the support edge is enclosed by the decorative layer and the carrier plate on the front surface of the carrier plate, and a layer of hot-melt adhesive designed to connect the decorative layer to the support edge being arranged between the support edge and the decorative layer, characterised in that the support edge arranged on the carrier plate has a sheet of parchment paper on the side thereof that faces away from the carrier plate, and in that the support edge further comprises a backing paper and a plurality of, in particular phenolic resin-impregnated, core plies between the backing paper and the parchment paper. a carrier plate which has an upper and a lower main surface, a front surface which extends from the upper main surface to the lower main surface, a support edge which is formed separately from the carrier plate and is arranged on the front surface of the carrier plate, and a decorative layer which is formed separately from the carrier plate and the support edge and extends from the upper surface of the carrier plate over the front surface of the carrier plate and the support edge to the lower surface of the support plate, the support edge is enclosed by the decorative layer and the carrier plate on the front surface of the carrier plate, and a layer of hot-melt adhesive designed to connect the decorative layer to the support edge being arranged between the support edge and the decorative layer, characterised in that the support edge arranged on the carrier plate has a sheet of parchment paper on the side thereof that faces away from the carrier plate, and in that the support edge further comprises a backing paper and a plurality of, in particular phenolic resin-impregnated, core plies between the backing paper and the parchment paper.
A microfluidic device component, comprising a planar substrate having a planar surface, wherein the planar surface comprises: a central portion, having a microfluidic channel or a microfluidic chamber defined within the central portion of the planar surface, a peripheral edge, and a groove having a cross-section defined in the planar surface, wherein the groove is discontinuous and aligns along the peripheral edge of the planar surface, wherein the groove comprises an interior surface and a recess defined therein, and characterized in that the recess joins the interior surface of the groove to the peripheral edge of the planar surface; a portion of the microfluidic channel extends to the peripheral edge of the planar surface thereby forming an outlet, wherein a first end and a second end of the groove flank the microfluidic channel; and the planar substrate further comprises a protrusion, wherein the portion of the microfluidic channel extends to a peripheral edge of the protrusion of the planar substrate thereby forming the outlet. a central portion, having a microfluidic channel or a microfluidic chamber defined within the central portion of the planar surface, a peripheral edge, and a groove having a cross-section defined in the planar surface, wherein the groove is discontinuous and aligns along the peripheral edge of the planar surface, wherein the groove comprises an interior surface and a recess defined therein, and characterized in that the recess joins the interior surface of the groove to the peripheral edge of the planar surface; a portion of the microfluidic channel extends to the peripheral edge of the planar surface thereby forming an outlet, wherein a first end and a second end of the groove flank the microfluidic channel; and the planar substrate further comprises a protrusion, wherein the portion of the microfluidic channel extends to a peripheral edge of the protrusion of the planar substrate thereby forming the outlet.
A stadium lighting system comprising: a plurality of luminaires for mounting in a stadium in accordance with a light plan containing aiming information for each luminaire; and a control system arranged to control said luminaires, the control system comprising: a data storage device storing the light plan; and a controller communicatively coupled to the data storage device, the controller being responsive to object tracking information for an object travelling across a pitch, wherein the controller is adapted to: determine a direction of travel of the object from the object tracking information: characterised in that the controller is further adapted to evaluate the aiming information for each luminaire to identify at least one luminaire which is arranged to generate a luminous output in an aiming direction coinciding with said direction of travel; and generate a dimming level adjustment signal for the at least one identified luminaire to reduce the intensity of said luminous output. a plurality of luminaires for mounting in a stadium in accordance with a light plan containing aiming information for each luminaire; and a control system arranged to control said luminaires, the control system comprising: a data storage device storing the light plan; and a controller communicatively coupled to the data storage device, the controller being responsive to object tracking information for an object travelling across a pitch, wherein the controller is adapted to: determine a direction of travel of the object from the object tracking information: characterised in that the controller is further adapted to evaluate the aiming information for each luminaire to identify at least one luminaire which is arranged to generate a luminous output in an aiming direction coinciding with said direction of travel; and generate a dimming level adjustment signal for the at least one identified luminaire to reduce the intensity of said luminous output. a data storage device storing the light plan; and a controller communicatively coupled to the data storage device, the controller being responsive to object tracking information for an object travelling across a pitch, wherein the controller is adapted to: determine a direction of travel of the object from the object tracking information: characterised in that the controller is further adapted to evaluate the aiming information for each luminaire to identify at least one luminaire which is arranged to generate a luminous output in an aiming direction coinciding with said direction of travel; and generate a dimming level adjustment signal for the at least one identified luminaire to reduce the intensity of said luminous output. determine a direction of travel of the object from the object tracking information: characterised in that the controller is further adapted to evaluate the aiming information for each luminaire to identify at least one luminaire which is arranged to generate a luminous output in an aiming direction coinciding with said direction of travel; and generate a dimming level adjustment signal for the at least one identified luminaire to reduce the intensity of said luminous output.
A method implemented by a host computing device comprising: detecting connection of a connector to a port of the host computing device based on signals conveyed via a pair of detection pins allocated in the connector; obtaining a logic state combination of high and low logic states conveyed via the pair of detection pins; determining a device type for the accessory device as a one wire device or a two wire device based upon the logic state combination; ascertaining an orientation of the connection of the connector to the port based on the signals, wherein the signals indicate the logic state combination for the pair of detection pins, the ascertaining including: when the device type is a one wire device, determining the orientation of the connection directly from the logic state combination; and when the device type is a two wire device, sampling resistor values for one or more identity resistors of the accessory device via the pair of detection pins to establish validity states indicative of the orientation; and configuring a switching mechanism of the host computing device to route signals according to the ascertained orientation and the logic state combination, wherein a one wire device is a device that comprises RX/TX that is combined on a single line for communicating and a two wire device is a device that comprises separate RX and TX lines for communicating. detecting connection of a connector to a port of the host computing device based on signals conveyed via a pair of detection pins allocated in the connector; obtaining a logic state combination of high and low logic states conveyed via the pair of detection pins; determining a device type for the accessory device as a one wire device or a two wire device based upon the logic state combination; ascertaining an orientation of the connection of the connector to the port based on the signals, wherein the signals indicate the logic state combination for the pair of detection pins, the ascertaining including: when the device type is a one wire device, determining the orientation of the connection directly from the logic state combination; and when the device type is a two wire device, sampling resistor values for one or more identity resistors of the accessory device via the pair of detection pins to establish validity states indicative of the orientation; and when the device type is a one wire device, determining the orientation of the connection directly from the logic state combination; and when the device type is a two wire device, sampling resistor values for one or more identity resistors of the accessory device via the pair of detection pins to establish validity states indicative of the orientation; and configuring a switching mechanism of the host computing device to route signals according to the ascertained orientation and the logic state combination, wherein a one wire device is a device that comprises RX/TX that is combined on a single line for communicating and a two wire device is a device that comprises separate RX and TX lines for communicating.
A compound of the formula: or a salt, enantiomer, diastereomer, or mixture thereof, wherein R 1, R 2, and R 3 are each independently a straight or branched C 1 -C 10 alkyl optionally substituted by at least one substituent each independently selected from hydroxy or halogen; R 4 is a straight or branched C 1 -C 5 alkyl substituted by a substituent of general formula: m and n are each independently is an integer selected from 0-5, wherein at least one of m or n is different than 0; X is selected from N, N + H, or N + (C 1 -C 10 alkyl); and Y is -O-, for use in the treatment of chronic pain or long lasting pain. R 1, R 2, and R 3 are each independently a straight or branched C 1 -C 10 alkyl optionally substituted by at least one substituent each independently selected from hydroxy or halogen; R 4 is a straight or branched C 1 -C 5 alkyl substituted by a substituent of general formula: m and n are each independently is an integer selected from 0-5, wherein at least one of m or n is different than 0; X is selected from N, N + H, or N + (C 1 -C 10 alkyl); and Y is -O-, for use in the treatment of chronic pain or long lasting pain. m and n are each independently is an integer selected from 0-5, wherein at least one of m or n is different than 0; X is selected from N, N + H, or N + (C 1 -C 10 alkyl); and Y is -O-, for use in the treatment of chronic pain or long lasting pain.
A first node for access and mobility management, for a Public Land Mobile Network, PLMN, the first node comprising: means for receiving, from a second node, information for identifying a stand-alone non-public network, SNPN, wherein the second node is communicatively coupled with the first node via a reference point of N2; and means for sending, to the second node, information of a warning message to be broadcast to a user equipment, UE, that accesses the SNPN. means for receiving, from a second node, information for identifying a stand-alone non-public network, SNPN, wherein the second node is communicatively coupled with the first node via a reference point of N2; and means for sending, to the second node, information of a warning message to be broadcast to a user equipment, UE, that accesses the SNPN.
A locking mechanism for releasably locking a lock bolt against axial movement, the mechanism comprising: an axially moveable member, arranged to move axially with the lock bolt; biasing means, arranged to bias the axially moveable member towards the lock bolt; rotation means in threaded engagement with the axially moveable member such that rotation of the rotation means causes axial movement of the axially moveable member, and an actuator assembly arranged to prevent rotation of said rotation means in a locked state; characterised by the actuator assembly comprising: a plunger having a tip and a drive means arranged to cause movement of the plunger relative to the rotation means, the actuator assembly arranged such that in a locked state the drive means causes the tip to engage with the rotation means such as to prevent rotation thereof, thus preventing axial movement of the axially moveable member, and wherein the actuator assembly comprises a solenoid assembly, the plunger is a solenoid plunger, the tip is a solenoid plunger tip and the drive means is a solenoid. an axially moveable member, arranged to move axially with the lock bolt; biasing means, arranged to bias the axially moveable member towards the lock bolt; rotation means in threaded engagement with the axially moveable member such that rotation of the rotation means causes axial movement of the axially moveable member, and an actuator assembly arranged to prevent rotation of said rotation means in a locked state; characterised by the actuator assembly comprising: a plunger having a tip and a drive means arranged to cause movement of the plunger relative to the rotation means, the actuator assembly arranged such that in a locked state the drive means causes the tip to engage with the rotation means such as to prevent rotation thereof, thus preventing axial movement of the axially moveable member, and wherein the actuator assembly comprises a solenoid assembly, the plunger is a solenoid plunger, the tip is a solenoid plunger tip and the drive means is a solenoid.