A compound of formula 1 wherein A is phenyl or pyridyl; R 1 is selected from the group consisting of R 1.1 is selected from the group consisting of C 1-4 -alkyl-, C 3-6 -cycloalkyl- and C 1-4 -haloalkyl-; R 1.2 is selected from the group consisting of H, NC-, O 2 N-, C 1-4 -alkyl-, C 3-6 -cycloalkyl-, C 1-4 -alkyl- C-, C 3-6 -cycloalkyl- C-, H 2 N- C-, C 1-4 -alkyl-NH- C-, C 3 - 6 -cycloalkyl-NH- C-, C 1-4 -alkyl-O- C-, C 3-6 -cycloalkyl-O- C-, H 2 N-(HO-N)C-, morpholinyl- C- and C 1-4 -alkyl-SO 2 -, or a 5-membered aromatic heterocycle containing one, two or three atoms selected from the group consisting of N, O and S; each ring optionally substituted with one or two residues selected independently from each other from the group consisting of C 1-4 -alkyl-, C 3-6 -cycloalkyl-, halogen and C 1-4 -haloalkyl-; R 1.3 is selected from the group consisting of H, C 1-4 -alkyl-, C 3-6 -cycloalkyl-, C 1-4 -alkyl-O-, C 3-6 -cycloalkyl-O-, benzyl-, H 2 N-, C 1-4 -alkyl-NH- and (C 1-4 -alkyl-) 2 N-; or two R 1.3 are together C 2-5 -alkylene forming a carbocyclic heteroring; R 1.4 is C 1-4 -alkyl- or C 3-6 -cycloalkyl-; R 1.5 is selected from the group consisting of H, NC-, C 1-4 -alkyl-, C 3-6 -cycloalkyl-and C 1-4 -alkyl-O-C 1-4 -alkyl-; x is 0 or 1; R 2 is phenyl or pyridyl, each ring optionally substituted with one or two residues selected independently from each other from the group consisting of C 1-4 -alkyl-, halogen and C 1-4 -haloalkyl-; R 3 is selected from the group consisting of C 1-4 -alkyl-, C 3-6 -cycloalkyl-, C 1-4 -haloalkyl- and C 1-4 -alkyl-O-C 1-4 -alkyl-; or phenyl or pyridyl, each ring optionally substituted with one or two residues selected independently from each other from the group consisting of NC-, halogen, C 1-4 -alkyl- and C 1-4 -haloalkyl-; Y is CH or N; or a pharmaceutically acceptable salt thereof. A is phenyl or pyridyl; R 1 is selected from the group consisting of R 1.1 is selected from the group consisting of C 1-4 -alkyl-, C 3-6 -cycloalkyl- and C 1-4 -haloalkyl-; R 1.2 is selected from the group consisting of H, NC-, O 2 N-, C 1-4 -alkyl-, C 3-6 -cycloalkyl-, C 1-4 -alkyl- C-, C 3-6 -cycloalkyl- C-, H 2 N- C-, C 1-4 -alkyl-NH- C-, C 3 - 6 -cycloalkyl-NH- C-, C 1-4 -alkyl-O- C-, C 3-6 -cycloalkyl-O- C-, H 2 N-(HO-N)C-, morpholinyl- C- and C 1-4 -alkyl-SO 2 -, or a 5-membered aromatic heterocycle containing one, two or three atoms selected from the group consisting of N, O and S; each ring optionally substituted with one or two residues selected independently from each other from the group consisting of C 1-4 -alkyl-, C 3-6 -cycloalkyl-, halogen and C 1-4 -haloalkyl-; R 1.3 is selected from the group consisting of H, C 1-4 -alkyl-, C 3-6 -cycloalkyl-, C 1-4 -alkyl-O-, C 3-6 -cycloalkyl-O-, benzyl-, H 2 N-, C 1-4 -alkyl-NH- and (C 1-4 -alkyl-) 2 N-; or two R 1.3 are together C 2-5 -alkylene forming a carbocyclic heteroring; R 1.4 is C 1-4 -alkyl- or C 3-6 -cycloalkyl-; R 1.5 is selected from the group consisting of H, NC-, C 1-4 -alkyl-, C 3-6 -cycloalkyl-and C 1-4 -alkyl-O-C 1-4 -alkyl-; x is 0 or 1; R 1.1 is selected from the group consisting of C 1-4 -alkyl-, C 3-6 -cycloalkyl- and C 1-4 -haloalkyl-; R 1.2 is selected from the group consisting of H, NC-, O 2 N-, C 1-4 -alkyl-, C 3-6 -cycloalkyl-, C 1-4 -alkyl- C-, C 3-6 -cycloalkyl- C-, H 2 N- C-, C 1-4 -alkyl-NH- C-, C 3 - 6 -cycloalkyl-NH- C-, C 1-4 -alkyl-O- C-, C 3-6 -cycloalkyl-O- C-, H 2 N-(HO-N)C-, morpholinyl- C- and C 1-4 -alkyl-SO 2 -, or a 5-membered aromatic heterocycle containing one, two or three atoms selected from the group consisting of N, O and S; each ring optionally substituted with one or two residues selected independently from each other from the group consisting of C 1-4 -alkyl-, C 3-6 -cycloalkyl-, halogen and C 1-4 -haloalkyl-; R 1.3 is selected from the group consisting of H, C 1-4 -alkyl-, C 3-6 -cycloalkyl-, C 1-4 -alkyl-O-, C 3-6 -cycloalkyl-O-, benzyl-, H 2 N-, C 1-4 -alkyl-NH- and (C 1-4 -alkyl-) 2 N-; or two R 1.3 are together C 2-5 -alkylene forming a carbocyclic heteroring; R 1.4 is C 1-4 -alkyl- or C 3-6 -cycloalkyl-; R 1.5 is selected from the group consisting of H, NC-, C 1-4 -alkyl-, C 3-6 -cycloalkyl-and C 1-4 -alkyl-O-C 1-4 -alkyl-; x is 0 or 1; R 2 is phenyl or pyridyl, each ring optionally substituted with one or two residues selected independently from each other from the group consisting of C 1-4 -alkyl-, halogen and C 1-4 -haloalkyl-; R 3 is selected from the group consisting of C 1-4 -alkyl-, C 3-6 -cycloalkyl-, C 1-4 -haloalkyl- and C 1-4 -alkyl-O-C 1-4 -alkyl-; or phenyl or pyridyl, each ring optionally substituted with one or two residues selected independently from each other from the group consisting of NC-, halogen, C 1-4 -alkyl- and C 1-4 -haloalkyl-; Y is CH or N;