mhurhangee/ep-ind-claims huggingface dataset:
A nanoparticle comprising: a core polyplex and a silica coating thereon, wherein said core polyplex comprises; one or more anionic polymers selected from the group consisting of poly(glutamic acid), a glycosaminoglycan, a glycoprotein, a polysaccharide, poly(mannuronic acid), poly(guluronic acid), heparin, heparin sulfate, chondroitin, chondroitin sulfate, keratan, keratan sulfate, aggrecan, poly(glucosamine), and any combination of two or more of the foregoing, one or more cationic polymers selected from the group consisting of poly(arginine), poly(lysine), poly(histidine), poly(ornithine), poly(citrulline), poly(ethylenimine), poly(aspartamide), a cationic polypeptoid, a charge-functionalized polyester, a cationic polysaccharide, an acetylated amino sugar, chitosan, or any combination of two or more of the foregoing, a cationic polypeptide which is a histone tail peptide, and a polynucleotide. a core polyplex and a silica coating thereon, wherein said core polyplex comprises; one or more anionic polymers selected from the group consisting of poly(glutamic acid), a glycosaminoglycan, a glycoprotein, a polysaccharide, poly(mannuronic acid), poly(guluronic acid), heparin, heparin sulfate, chondroitin, chondroitin sulfate, keratan, keratan sulfate, aggrecan, poly(glucosamine), and any combination of two or more of the foregoing, one or more cationic polymers selected from the group consisting of poly(arginine), poly(lysine), poly(histidine), poly(ornithine), poly(citrulline), poly(ethylenimine), poly(aspartamide), a cationic polypeptoid, a charge-functionalized polyester, a cationic polysaccharide, an acetylated amino sugar, chitosan, or any combination of two or more of the foregoing, a cationic polypeptide which is a histone tail peptide, and a polynucleotide.
A TGF-β ligand trap comprising a TGF-β ligand binding domain of a TGF-β type II receptor and an Fc domain of an immunoglobulin for use in a method of treating, preventing, or reducing the progression rate of pulmonary arterial hypertension in a subject, wherein the method comprises administering a therapeutically effective amount of the TGF-β ligand trap to the subject.
Heat-conducting profile (1, 21, 31, 41) which is used for the transfer of heat to or from a pipe which can carry a heat transfer medium, and a groove (1.1, 21.1, 31.1, 41.1, 41.1) with a bottom opening area into which the pipe can be clamped, wherein the wall which abuts the clamped pipe as a boundary of the groove (1.1, 21.1, 31.1, 41.1) displays at least two partial surface areas (1.1.1, 1.1.2, 21.1.1, 21.1.2, 31.1.1, 31.1.2, 31.1.3), wherein these partial surface areas are not directly connected to each other, but through multi-layered profile walls (1.3, 1.4, 21.3, 31.3, 31.13, 41.3, 41.13) of the heat-conducting profile (1, 21, 31, 41) which project from the intended contact surface to the pipe, wherein two of the layers of these profile walls are connected to each other only in a boundary area located at a distance from the groove, wherein one layer in each case is directly connected to one of the said partial surface areas and one other layer in each case to another of these partial surface areas, characterised by the fact that for the insertion of the pipe in the groove of the heat transfer profile, not only the groove walls and partial surface areas of the heat transfer profile are elastically deformed, but also the profile walls (1.3, 1.4, 21.3, 31.3, 31.13, 41.3, 41.13).
A pipe cutting apparatus, comprising a substantially rigid annular frame adapted to be coupled to a pipe to be cut; a cutting means for cutting said pipe being removably associated with said annular frame, and a movement means adapted to move said cutting means with respect to said annular frame about an axis of revolution configured to substantially coincide with the longitudinal axis of said pipe; said annular frame comprising at least one annular rail which comprises two or more rail members (9a, 9b) shaped as an annular sector, said rail members (9a, 9b) being connectable to each other by mating means so as not to break the continuity of the profile of said annular rail and maintain the lateral alignment of said rail members (9a, 9b); said cutting means comprising a carriage that is slidingly and removably associated with said annular rail; said carriage having engagement members which can selectively engage said annular rail; said engagement members comprising at least one pair of pins rotatably mounted on said carriage about second axes of rotation which are substantially parallel to said axis of revolution; said pins being adapted to engage an inner cylindrical edge of said annular rail; said apparatus being characterized in that said pins are accommodated in respective seats formed on supporting members slidingly mounted on said carriage; said pins being rotatable with respect to said second axes of rotation and being able to slide selectively with respect to said second axes of rotation.
A polymer support comprising a 6-amino 6-deoxy chitosan polymer with a linker provided on at least some of the amine groups of the polymer, the polymer support being characterised in that the linker is introduced as a heterobifunctional moiety capable of covalent coupling with the amino functional groups of the polymer on one end and a functional molecule on the other end, wherein the functional molecule is a metal complex.
An arrangement for monitoring the state of surge arresters which are interconnected, by means of releasable and/or non-releasable electrical contacts and connections (S1; S2; 5; 6), in the path to be protected or in front of an apparatus to be protected, the voltage drop across the electrical contacts and connections (S1; 5) being monitored and, to this end, a monitoring unit (7; 8) being connected in parallel with the contacts and connections, wherein, as the voltage drop across the contacts and connections increases, the extent of the current rise in the parallel path is evaluated by means of the monitoring unit (7; 8) and, when a limit value is exceeded, an indicating device or fault signaling unit is able to be activated, characterized in that the respective surge arrester includes a base part having electrical connection terminals (A1; A2) and a plug-in part adapted to be received by the base part, wherein releasable electrical contacts are provided between the base part and the plug-in part, at least one arrester means having a thermal disconnecting device is formed in the plug-in part, furthermore, the monitoring unit is located in the base part and is connected to one of the external connection terminals on the one hand and to the connection of the disconnecting device to the arrester means on the other hand, such that in the event of increasing contact transition resistances between the base part and the plug-in part (11; 13) and/or at the internal connections in the plug-in part, the current in the parallel path and thus the current flowing through the monitoring unit increases, whereby the indicating device or the fault signaling unit is activated. the voltage drop across the electrical contacts and connections (S1; 5) being monitored and, to this end, a monitoring unit (7; 8) being connected in parallel with the contacts and connections, wherein, as the voltage drop across the contacts and connections increases, the extent of the current rise in the parallel path is evaluated by means of the monitoring unit (7; 8) and, when a limit value is exceeded, an indicating device or fault signaling unit is able to be activated, characterized in that the respective surge arrester includes a base part having electrical connection terminals (A1; A2) and a plug-in part adapted to be received by the base part, wherein releasable electrical contacts are provided between the base part and the plug-in part, at least one arrester means having a thermal disconnecting device is formed in the plug-in part, furthermore, the monitoring unit is located in the base part and is connected to one of the external connection terminals on the one hand and to the connection of the disconnecting device to the arrester means on the other hand, such that in the event of increasing contact transition resistances between the base part and the plug-in part (11; 13) and/or at the internal connections in the plug-in part, the current in the parallel path and thus the current flowing through the monitoring unit increases, whereby the indicating device or the fault signaling unit is activated.
A compressible adjunct for a staple cartridge, comprising: a first portion; a second portion; and a middle portion, wherein the middle portion is disposed between the first portion and the second portion, and wherein the middle portion comprises: a first pillar; a second pillar, wherein the first pillar and the second pillar extend along their longitudinal axis from the first portion to the second portion; and an interconnecting member, wherein the interconnecting member is configured to engage at least the first pillar and the second pillar, characterized in that the first pillar differs from the second pillar in at least one property such that when the compressible adjunct is compressed by a force, the first pillar is configured to deflect a first deflection and the second pillar is configured to deflect a second deflection, and wherein the first deflection differs from the second deflection. a first portion; a second portion; and a middle portion, wherein the middle portion is disposed between the first portion and the second portion, and wherein the middle portion comprises: a first pillar; a second pillar, wherein the first pillar and the second pillar extend along their longitudinal axis from the first portion to the second portion; and an interconnecting member, wherein the interconnecting member is configured to engage at least the first pillar and the second pillar, characterized in that the first pillar differs from the second pillar in at least one property such that when the compressible adjunct is compressed by a force, the first pillar is configured to deflect a first deflection and the second pillar is configured to deflect a second deflection, and wherein the first deflection differs from the second deflection. a first pillar; a second pillar, wherein the first pillar and the second pillar extend along their longitudinal axis from the first portion to the second portion; and an interconnecting member, wherein the interconnecting member is configured to engage at least the first pillar and the second pillar, characterized in that the first pillar differs from the second pillar in at least one property such that when the compressible adjunct is compressed by a force, the first pillar is configured to deflect a first deflection and the second pillar is configured to deflect a second deflection, and wherein the first deflection differs from the second deflection.
A sole structure for an article of footwear comprising: a midsole comprising a first compressible material; an insert comprising a second compressible material that differs from the first compressible material; and an outsole secured with the midsole such that the insert is located between the midsole and the outsole; wherein exterior sidewall surfaces of the midsole and outsole combine to form an arcuate profile along toe, heel, medial and lateral sides of the sole structure, the midsole includes a groove located at a heel side location and extending from a top edge to a midsole bottom, traversing both a midsole top portion and a midsole bottom portion, and the outsole includes a groove located at the heel side location of the outsole and aligned to the corresponding midsole groove. a midsole comprising a first compressible material; an insert comprising a second compressible material that differs from the first compressible material; and an outsole secured with the midsole such that the insert is located between the midsole and the outsole; wherein exterior sidewall surfaces of the midsole and outsole combine to form an arcuate profile along toe, heel, medial and lateral sides of the sole structure, the midsole includes a groove located at a heel side location and extending from a top edge to a midsole bottom, traversing both a midsole top portion and a midsole bottom portion, and the outsole includes a groove located at the heel side location of the outsole and aligned to the corresponding midsole groove.
A process for manufacturing a flat lightweight material formed essentially from reinforcing fibres (22, 26) and thermoplastic material in which process, in a first step, the thermoplastic material provided as a matrix for the fibre composite material (22, 26) of the lightweight material is injected into a still empty press mould and in a second step, after opening the press mould, the reinforcing fibres (22, 26) provided as a reinforcement (22, 26) for the fibre composite material and/or the lightweight material and clamped in a frame prepared outside of the press mould are introduced into the mould together with the frame, after which the press mould is closed in a third step and the reinforcing fibres (22, 26) are impregnated with the thermoplastic matrix by pressing, wherein the process for introducing the reinforcing fibres (22, 26) uses a frame, in which the reinforcing fibres (22, 26) are clamped outside the press mould and with which the reinforcing fibres (22, 26) are introduced into the pressing tool, and wherein the reinforcing fibres (22, 26) are clamped in the frame in a load-appropriate orientation in accordance with the material properties of the lightweight material, characterized in that the reinforcing fibres (22, 26) are clamped in the frame at a density and/or at distances from one another that are load-appropriate in accordance with the material properties of the lightweight material, and in that the reinforcing fibres (22, 26) are clamped to the frame and/or are introduced into the press mould in the form of dry or pre-wetted filament yarns or rovings.
A support garment for a pregnant woman, comprising tights and a belt assembled together, the tights being a medical compression orthosis, everyday tights, sport tights or comfort compression tights, characterized in that the belt comprises: - a first band which extends around the waist in an uninterrupted manner between two ends (31, 32) and which is intended to come into contact with the skin, on the abdomen and the back of the pregnant woman, by putting it on or by employing adjustment means disposed at the two ends (31, 32), and - a second band made of a material that is less elastic than the first band and disposed on the first band as a reinforcement in order to support the weight of the forwardly swelling abdomen and thus relieve the back of the pregnant woman. - a first band which extends around the waist in an uninterrupted manner between two ends (31, 32) and which is intended to come into contact with the skin, on the abdomen and the back of the pregnant woman, by putting it on or by employing adjustment means disposed at the two ends (31, 32), and - a second band made of a material that is less elastic than the first band and disposed on the first band as a reinforcement in order to support the weight of the forwardly swelling abdomen and thus relieve the back of the pregnant woman.
A method of printing including testing the status of a printhead having a plurality of printing elements each of which is operable to transfer a marking medium from a web to a substrate, wherein the method includes testing the status of each printing element, and providing a preview of an image to be printed, characterised in that the image includes more than one component (30a, 30b) and, in the event that the print quality of the image is inadequate owing to the position of one or more damaged printing elements (14a, 14b) relative to the image to be printed, the method includes adjusting the position of at least one component (30a, 30b) relative to the or each other component (30a, 30b), such that at least one damaged element (14a, 14b) falls outside a boundary of a component (30a, 30b) of the image.
A method for managing a backup procedure of a transaction backup mode, which can be activated in the event of a computer attack or a failure on a transaction network, implemented by an electronic device able to carry out a transaction in a normal mode or in the backup mode, said method comprising the following steps: • receiving (F340, F455) a command of activation of said procedure of the backup mode, comprising an identifier of the procedure and a first encrypted data, • verifying the activation command, comprising a verification of said first encrypted data, • if the verification of the command is successful, activating the backup procedure, • after the activation of the backup procedure and following an initialization of a transaction between the electronic device and a reader, sending a message to said reader comprising a request to consult a normal mode server of the transaction network, and • upon receipt of a message indicating that the consultation of the server of the normal mode has failed, sending to said reader a cryptogram comprising at least one information on said procedure. • receiving (F340, F455) a command of activation of said procedure of the backup mode, comprising an identifier of the procedure and a first encrypted data, • verifying the activation command, comprising a verification of said first encrypted data, • if the verification of the command is successful, activating the backup procedure, • after the activation of the backup procedure and following an initialization of a transaction between the electronic device and a reader, sending a message to said reader comprising a request to consult a normal mode server of the transaction network, and • upon receipt of a message indicating that the consultation of the server of the normal mode has failed, sending to said reader a cryptogram comprising at least one information on said procedure.
A pressure intensifier for fluids, in particular for liquids, comprising a cylinder block in which a pressure intensifier piston and a control piston move cyclically, wherein the pressure intensifier piston forms a high-pressure working chamber and a low-pressure working chamber in the cylinder block and the cylinder block has a low-pressure connection for feeding in low-pressure fluid from outside, a high-pressure connection for discharging higher-pressure working fluid towards the outside and a connection for discharging fluid whose working capacity in the pressure intensifier is exhausted, characterized in that the cylinder block has a coupling portion rigidly connected with it, which can be inserted into a receiving bore of a hydraulic block and fixed there, so that the receiving bore encloses the coupling portion, wherein the coupling portion has at least two fluid transfer regions (104, 105, 113) fluidically separated by a seal, for exchanging fluid between the pressure intensifier and the hydraulic block into which it is inserted.
Apparatus including a valve component to allow the passage of air or gas therethrough and a pipeline along which water or effluent liquid passes and to which the said valve component is fitted and operable in communication therewith to allow, when open, the passage of air or gas through the same, said apparatus provided for the continuous monitoring of the condition of said valve component (4; 53), said apparatus further including memory means, collection means and data processing means and a housing in which at least first and second detecting devices (58, 56, 32) are fitted, said housing located on, or adjacent to, the said valve component (4; 53) in order to detect a change in condition in the form of a level of fluid within the pipeline at the location of the valve component (4; 53) reaching a predetermined level to cause operation of the valve component to allow air into the pipeline or a level to cause operation of the valve component (4; 53) to allow the release of gas or air from the pipeline and wherein the first detecting device is a vibration detector which is activated by the mechanical operation of the valve component (4; 53), and moves the said memory means, collection means and data processing means of the apparatus from a dormant to an active mode and activates the second detecting device (56, 32), which is an acoustic device, to detect and store data representative of the noise heard and said vibration, in said memory means at the location and/or made available to a remote location and in either case the data is collected by the collection means connected to the valve component to determine if the data representative of the detected noise heard by the said acoustic device (56, 32) is a result of the operation of the valve component (4; 53) and said data processing means collect, process and record the vibration and time at which the vibration is detected.
A signal processing system comprising: a receiving unit configured to receive at least one signal that comprises a plurality of multipath components; a verification unit configured to verify content that is modulated on at least one multipath component under test by correlating the at least one multipath component under test with a reference signal derived from one or more of said plurality of multipath components, to determine whether the multipath component under test is genuine for identifying a genuine earliest multipath component of the plurality of multipath components. a receiving unit configured to receive at least one signal that comprises a plurality of multipath components; a verification unit configured to verify content that is modulated on at least one multipath component under test by correlating the at least one multipath component under test with a reference signal derived from one or more of said plurality of multipath components, to determine whether the multipath component under test is genuine for identifying a genuine earliest multipath component of the plurality of multipath components.
A bioreactor for modulating lymphocytes and suppressing autoreactive T cells, comprising: a chamber having at least one positively charged and hydrophobic substrate surface; a population of stem cells that is not derived from the inner cell mass of a blastocyst attached to the substrate surface, wherein the stem cells are characterized by: (a) displaying embryonic stem cell characteristics; (b) displaying hematopoietic cell characteristics as being positive for leukocyte common antigen CD45; (c) not expressing the CD34 marker; (d) displaying low immunogenicity; or (e) expressing autoimmune regulator; an inlet conduit for introducing lymphocytes into the chamber for co-culturing with the stem cells, and the lymphocytes are free from plasma before being introduced into the chamber, and an outlet conduit for extracting treated lymphocytes following co-culturing with the stem cells, wherein the stem cells are capable of, and configured for, modulating the lymphocytes and suppressing autoreactive T cells by co-culturing with the introduced lymphocytes that are free from plasma. a chamber having at least one positively charged and hydrophobic substrate surface; a population of stem cells that is not derived from the inner cell mass of a blastocyst attached to the substrate surface, wherein the stem cells are characterized by: (a) displaying embryonic stem cell characteristics; (b) displaying hematopoietic cell characteristics as being positive for leukocyte common antigen CD45; (c) not expressing the CD34 marker; (d) displaying low immunogenicity; or (e) expressing autoimmune regulator; an inlet conduit for introducing lymphocytes into the chamber for co-culturing with the stem cells, and the lymphocytes are free from plasma before being introduced into the chamber, and an outlet conduit for extracting treated lymphocytes following co-culturing with the stem cells, wherein the stem cells are capable of, and configured for, modulating the lymphocytes and suppressing autoreactive T cells by co-culturing with the introduced lymphocytes that are free from plasma.