A compound of general formula: wherein each R 1 may be a -COOH; a H; a halogen; a tetrazol; a -SO 2 -NH-C(=O)-R'; a-C(=O)NH-SO 2 -R'; or a -SO 2 -OH with the proviso that only one of them must always represent a-COOH; or tetrazol or-SO 2 -NH-C(=O)-R' or-C(=O)NH-SO 2 -R' or -SO 2 -OH, each R 2 is independently selected from the group consisting of H; a halogen; C 1-6 -alkyl; or -O-C 1-6 -alkyl, with the proviso that at least one R 2 must be different from H R 3 is selected from H; or a C 1-6 -alkyl; R 4 is a halogen or a C 1-6 -alkyl; A, B and C independently represents a CR a or a N; Y is a -NR 5 R 6; an -OR 7; a phenyl, optionally substituted by at least one R b; a benzyl optionally substituted by at least one R b; a 5- or 6-membered heterocyclic ring, optionally substituted by at least one R b, containing at least one heteroatom selected from N, O or S; a C 1-4 -alkylene-C 3-6 -cycloalkyl; or a C 2-6 -alkyl; R 5 and R 6 are independently selected from H; a C 1-6 -alkyl; a benzyl; a C 3-6 cycloalkyl; -C 1-4 -alkylene-C 3-6 cycloalkyl; or -C 1-4 -alkylene-C 1-6 -alkyloxy; R 7 is a H, a C 1-6 -alkyl, a benzyl optionally substituted by at least one R c; or a -C 1-4 -alkylene-C 3-6 cycloalkyl; R' is independently selected from a hydrogen; C 1-6 -alkyl; an optionally substituted phenyl; or -N(CH 3) 2; R a is a H or a C 1-6 -alkyl; each R b is independently a H; a C 1-6 -alkyl; a halogen; a -CN; a trihalo-C 1-6 -alkyl; a-CONR 8 R 9; an -OR 10 or -C 1-4 -alkylene-OR 11; each R c is independently a H; a C 1-6 -alkyl; or a halogen; R 8 and R 9 are independently selected from H; or a C 1-6 -alkyl; R 10 and R 11 are independently selected from H; or a C 1-6 -alkyl; with the proviso that when R 1 is COOH in meta position and R 2 is either methyl or Cl or when R 1 is COOH in para position and R 2 is methyl, R 7 is not methyl and R 4 is not Br, and with the proviso that when R 1 is a tetrazol the circumstance where Y is methoxy or pirrolidinyl and R 4 is Br or Cl is not possible, and the salts and solvates thereof. each R 1 may be a -COOH; a H; a halogen; a tetrazol; a -SO 2 -NH-C(=O)-R'; a-C(=O)NH-SO 2 -R'; or a -SO 2 -OH with the proviso that only one of them must always represent a-COOH; or tetrazol or-SO 2 -NH-C(=O)-R' or-C(=O)NH-SO 2 -R' or -SO 2 -OH, each R 2 is independently selected from the group consisting of H; a halogen; C 1-6 -alkyl; or -O-C 1-6 -alkyl, with the proviso that at least one R 2 must be different from H R 3 is selected from H; or a C 1-6 -alkyl; R 4 is a halogen or a C 1-6 -alkyl; A, B and C independently represents a CR a or a N; Y is a -NR 5 R 6; an -OR 7; a phenyl, optionally substituted by at least one R b; a benzyl optionally substituted by at least one R b; a 5- or 6-membered heterocyclic ring, optionally substituted by at least one R b, containing at least one heteroatom selected from N, O or S; a C 1-4 -alkylene-C 3-6 -cycloalkyl; or a C 2-6 -alkyl; R 5 and R 6 are independently selected from H; a C 1-6 -alkyl; a benzyl; a C 3-6 cycloalkyl; -C 1-4 -alkylene-C 3-6 cycloalkyl; or -C 1-4 -alkylene-C 1-6 -alkyloxy; R 7 is a H, a C 1-6 -alkyl, a benzyl optionally substituted by at least one R c; or a -C 1-4 -alkylene-C 3-6 cycloalkyl; R' is independently selected from a hydrogen; C 1-6 -alkyl; an optionally substituted phenyl; or -N(CH 3) 2; R a is a H or a C 1-6 -alkyl; each R b is independently a H; a C 1-6 -alkyl; a halogen; a -CN; a trihalo-C 1-6 -alkyl; a-CONR 8 R 9; an -OR 10 or -C 1-4 -alkylene-OR 11; each R c is independently a H; a C 1-6 -alkyl; or a halogen; R 8 and R 9 are independently selected from H; or a C 1-6 -alkyl; R 10 and R 11 are independently selected from H; or a C 1-6 -alkyl; with the proviso that when R 1 is COOH in meta position and R 2 is either methyl or Cl or when R 1 is COOH in para position and R 2 is methyl, R 7 is not methyl and R 4 is not Br, and with the proviso that when R 1 is a tetrazol the circumstance where Y is methoxy or pirrolidinyl and R 4 is Br or Cl is not possible,