A compound of Formula wherein A is phenyl, thienyl, or C 5-7 cycloalkyl; provided that when A is phenyl, R 2 is other than 2-chloro, 2-C 1-4 alkoxy, 4-C 1-4 alkoxy, 2-C 1-4 alkoxycarbonyl, or 4-C 1-4 alkoxycarbonyl; or, when A is phenyl, L is -N(R 3)(CH 2) n -, and R 1 and L are attached to adjacent carbon atoms of phenyl, R 1 and R 3 are optionally taken with the atoms to which they are attached to form dihydro-indol-1-yl or dihydro-quinolin-1-yl; R 1 is one to three substituents selected from the group consisting of hydrogen, C 1-4 alkyl, C 1-4 alkoxy, fluoro, chloro, and hydroxy; L is -Z -(CH 2) n - or -CH 2 -; n is 0 or 1; Z is O, S, or NR 3; provided that when Z is O or S, A is phenyl; R 2 is hydrogen, C 1-4 alkyl, C 1-4 alkoxy, trifluoromethyl, chloro, fluoro, bromo, carboxy, or C 1-4 alkoxycarbonyl; R 3 is hydrogen or C 1-3 alkyl; R 4 is hydrogen or C 1-4 alkyl; R 5 is naphthyl, indanyl, tetralinyl, or a 9 to 10-membered heteroaryl selected from the group consisting of benzimidazolyl, cinnolinyl, 1 H -indazolyl, indolyl, isoindolyl, isoquinolinyl, naphthyridinyl, phthalazinyl, quinazolinyl, quinolinyl, and quinoxalinyl; wherein R 5 is optionally substituted with 1 to 2 substituents independently selected from the group consisting of C 1-4 alkyl, hydroxy, C 1-4 alkoxy, trifluoromethyl, chloro, fluoro, bromo, carboxy, C 1-4 alkoxycarbonyl, and cyano; and enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof; provided that a compound of Formula is other than a compound wherein A is phenyl, R 1 is 3-chloro, R 2 is 4-trifluoromethyl, L is -Z-(CH 2) n -, n is 1, Z is NR 3, R 3 is hydrogen, R 4 is hydrogen, and R 5 is isoquinolin-5-yl; a compound wherein A is phenyl, R 1 is 2-fluoro, R 2 is 4-trifluoromethyl, L is -Z-(CH 2) n -, n is 0, Z is NR 3, R 3 is hydrogen, R 4 is hydrogen, and R 5 is indol-4-yl; and a compound wherein A is phenyl, R 1 is 4-methoxy, R 2 is 4-chloro, L is -Z-(CH 2) n -, n is 0, Z is NR 3, R 3 is hydrogen, R 4 is hydrogen, and R 5 is isoquinolin-5-yl. A is phenyl, thienyl, or C 5-7 cycloalkyl; provided that when A is phenyl, R 2 is other than 2-chloro, 2-C 1-4 alkoxy, 4-C 1-4 alkoxy, 2-C 1-4 alkoxycarbonyl, or 4-C 1-4 alkoxycarbonyl; or, when A is phenyl, L is -N(R 3)(CH 2) n -, and R 1 and L are attached to adjacent carbon atoms of phenyl, R 1 and R 3 are optionally taken with the atoms to which they are attached to form dihydro-indol-1-yl or dihydro-quinolin-1-yl; R 1 is one to three substituents selected from the group consisting of hydrogen, C 1-4 alkyl, C 1-4 alkoxy, fluoro, chloro, and hydroxy; L is -Z -(CH 2) n - or -CH 2 -; n is 0 or 1; Z is O, S, or NR 3; provided that when Z is O or S, A is phenyl; R 2 is hydrogen, C 1-4 alkyl, C 1-4 alkoxy, trifluoromethyl, chloro, fluoro, bromo, carboxy, or C 1-4 alkoxycarbonyl; R 3 is hydrogen or C 1-3 alkyl; R 4 is hydrogen or C 1-4 alkyl; R 5 is naphthyl, indanyl, tetralinyl, or a 9 to 10-membered heteroaryl selected from the group consisting of benzimidazolyl, cinnolinyl, 1 H -indazolyl, indolyl, isoindolyl, isoquinolinyl, naphthyridinyl, phthalazinyl, quinazolinyl, quinolinyl, and quinoxalinyl; wherein R 5 is optionally substituted with 1 to 2 substituents independently selected from the group consisting of C 1-4 alkyl, hydroxy, C 1-4 alkoxy, trifluoromethyl, chloro, fluoro, bromo, carboxy, C 1-4 alkoxycarbonyl, and cyano; and enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof; provided that a compound of Formula is other than a compound wherein A is phenyl, R 1 is 3-chloro, R 2 is 4-trifluoromethyl, L is -Z-(CH 2) n -, n is 1, Z is NR 3, R 3 is hydrogen, R 4 is hydrogen, and R 5 is isoquinolin-5-yl; a compound wherein A is phenyl, R 1 is 2-fluoro, R 2 is 4-trifluoromethyl, L is -Z-(CH 2) n -, n is 0, Z is NR 3, R 3 is hydrogen, R 4 is hydrogen, and R 5 is indol-4-yl; and a compound wherein A is phenyl, R 1 is 4-methoxy, R 2 is 4-chloro, L is -Z-(CH 2) n -, n is 0, Z is NR 3, R 3 is hydrogen, R 4 is hydrogen, and R 5 is isoquinolin-5-yl.