A pressure independent control valve PICV for controlling the flow of a liquid medium, especially suitable for use in heating or cooling systems, comprising: a body defined by a tubular element comprising an inlet duct and an outlet duct coaxial with each other, a central body arranged in an intermediate position and with its axis substantially inclined with respect to said inlet duct and to said outlet duct and comprising an upstream chamber and a downstream chamber coaxial with each other and in communication through an adjustment orifice, said upstream chamber and downstream chamber suitable for housing, respectively, a first functional group defined by a control device for controlling the differential pressure between upstream of the adjustment orifice, in correspondence of the upstream chamber, and downstream of said adjustment orifice, in correspondence with the outlet duct, and a second functional group coaxial to said first functional group and defined by an adjustment device suitable for increasing or decreasing the area available for the liquid flow through the adjustment orifice, the pressure independent control valve being characterized by the fact that: the adjustment device comprises a single actuation means both rotationally operable for a pre-adjustment of the fluid passage area of the adjustment orifice and also operable in axial translation for a further adjustment of said area with a resulting modulation of liquid flow, said actuation means of the adjustment device being defined by a rod longitudinally developed, equipped at the end facing the adjustment orifice with a threaded profile suitable for being coupled with a corresponding threaded profile of a conical tip so as to define a screw-drive coupling, the actuation means providing both an axial forward movement of said conical tip by means of a manual rotation of the rod and a rigid translation of the rod and conical tip assembly in case of axial translation of the rod, and by the fact that said adjustment device further comprises a disk-shaped element mounted on the rod which allows the display of the pre-adjustment set for the valve and avoids the accidental variation of said pre-adjustment. a body defined by a tubular element comprising an inlet duct and an outlet duct coaxial with each other, a central body arranged in an intermediate position and with its axis substantially inclined with respect to said inlet duct and to said outlet duct and comprising an upstream chamber and a downstream chamber coaxial with each other and in communication through an adjustment orifice, said upstream chamber and downstream chamber suitable for housing, respectively, a first functional group defined by a control device for controlling the differential pressure between upstream of the adjustment orifice, in correspondence of the upstream chamber, and downstream of said adjustment orifice, in correspondence with the outlet duct, and a second functional group coaxial to said first functional group and defined by an adjustment device suitable for increasing or decreasing the area available for the liquid flow through the adjustment orifice, the pressure independent control valve being characterized by the fact that: the adjustment device comprises a single actuation means both rotationally operable for a pre-adjustment of the fluid passage area of the adjustment orifice and also operable in axial translation for a further adjustment of said area with a resulting modulation of liquid flow, said actuation means of the adjustment device being defined by a rod longitudinally developed, equipped at the end facing the adjustment orifice with a threaded profile suitable for being coupled with a corresponding threaded profile of a conical tip so as to define a screw-drive coupling, the actuation means providing both an axial forward movement of said conical tip by means of a manual rotation of the rod and a rigid translation of the rod and conical tip assembly in case of axial translation of the rod, and by the fact that said adjustment device further comprises a disk-shaped element mounted on the rod which allows the display of the pre-adjustment set for the valve and avoids the accidental variation of said pre-adjustment. the adjustment device comprises a single actuation means both rotationally operable for a pre-adjustment of the fluid passage area of the adjustment orifice and also operable in axial translation for a further adjustment of said area with a resulting modulation of liquid flow, said actuation means of the adjustment device being defined by a rod longitudinally developed, equipped at the end facing the adjustment orifice with a threaded profile suitable for being coupled with a corresponding threaded profile of a conical tip so as to define a screw-drive coupling, the actuation means providing both an axial forward movement of said conical tip by means of a manual rotation of the rod and a rigid translation of the rod and conical tip assembly in case of axial translation of the rod, and by the fact that said adjustment device further comprises a disk-shaped element mounted on the rod which allows the display of the pre-adjustment set for the valve and avoids the accidental variation of said pre-adjustment.