An air cleaner assembly comprising: (a) a housing including: a housing body; and, an access cover; (i) the housing body having: an open service access end; and, a main filter cartridge sealing shelf recessed from the open service access end; (ii) the access cover comprising a precleaner assembly including a flow separator tube arrangement comprising a plurality of flow separator tubes; the access cover being removably mounted on the housing body over the service access end and with the flow separator tube arrangement projecting into the housing body to a location surrounded by the housing body; and, (iii) the housing including: an air flow inlet arrangement; an air flow outlet arrangement; and, a contaminant evacuation port arrangement; and, (b) a main filter cartridge removably positioned within the housing body; the main filter cartridge comprising; (i) a media pack having an inlet end and an opposite outlet end; and, (ii) a housing seal arrangement comprising a perimeter pinch seal removably positioned sealingly biased against the main cartridge sealing shelf. (a) a housing including: a housing body; and, an access cover; (i) the housing body having: an open service access end; and, a main filter cartridge sealing shelf recessed from the open service access end; (ii) the access cover comprising a precleaner assembly including a flow separator tube arrangement comprising a plurality of flow separator tubes; the access cover being removably mounted on the housing body over the service access end and with the flow separator tube arrangement projecting into the housing body to a location surrounded by the housing body; and, (iii) the housing including: an air flow inlet arrangement; an air flow outlet arrangement; and, a contaminant evacuation port arrangement; and, (i) the housing body having: an open service access end; and, a main filter cartridge sealing shelf recessed from the open service access end; (ii) the access cover comprising a precleaner assembly including a flow separator tube arrangement comprising a plurality of flow separator tubes; the access cover being removably mounted on the housing body over the service access end and with the flow separator tube arrangement projecting into the housing body to a location surrounded by the housing body; and, the access cover being removably mounted on the housing body over the service access end and with the flow separator tube arrangement projecting into the housing body to a location surrounded by the housing body; and, (iii) the housing including: an air flow inlet arrangement; an air flow outlet arrangement; and, a contaminant evacuation port arrangement; and, (b) a main filter cartridge removably positioned within the housing body; the main filter cartridge comprising; (i) a media pack having an inlet end and an opposite outlet end; and, (ii) a housing seal arrangement comprising a perimeter pinch seal removably positioned sealingly biased against the main cartridge sealing shelf. (i) a media pack having an inlet end and an opposite outlet end; and, (ii) a housing seal arrangement comprising a perimeter pinch seal removably positioned sealingly biased against the main cartridge sealing shelf.