mhurhangee/ep-ind-claims huggingface dataset:
Process for the preparation of high purity Latanoprost acid of the formula II a. in which the amount of the isomeric impurities is individually not more than 0.15%, by reacting the lactol of formula III with the phosphoran obtained from the triphenyl(carboxybutyl)phosphonium bromide of formula IV in Wittig reaction in the presence of KOBu t and THF; characterized by purifying the crude Latanoprost acid of the formula II a. by normal phase gravitational silica gel chromatography, wherein hexane:isopropanol:acetic acid mixture is applied as eluent in a ratio of (91-73%): (24-8.7%): (0.1-4.3%); and the applied silica gel is a spherical silica gel having average particle size in a range of 75-150 micrometer. characterized by purifying the crude Latanoprost acid of the formula II a. by normal phase gravitational silica gel chromatography, wherein hexane:isopropanol:acetic acid mixture is applied as eluent in a ratio of (91-73%): (24-8.7%): (0.1-4.3%); and the applied silica gel is a spherical silica gel having average particle size in a range of 75-150 micrometer.
Process for producing an analytical aid for the detection of at least one analyte in a sample, more particularly a body fluid, wherein the analytical aid comprises at least one housing and at least one test element comprising at least one test chemistry, wherein the process comprises the following steps: a) providing the test element comprising the test chemistry; and b) producing at least one housing part of the housing by means of at least one shaping process, during which the test element comprising the test chemistry is connected to the housing part, wherein, in process step b), the test element is connected to the housing part such that at least one surface of the test chemistry as test field area for input of the sample remains uncovered by a housing material of the housing part, wherein the housing is configured such that at least one observation window is produced in the housing, wherein the test field area is optically monitorable through the observation window of the housing wherein the process is carried out such that the housing forms at least one chamber, wherein the test field area faces an interior space of the chamber. a) providing the test element comprising the test chemistry; and b) producing at least one housing part of the housing by means of at least one shaping process, during which the test element comprising the test chemistry is connected to the housing part, wherein, in process step b), the test element is connected to the housing part such that at least one surface of the test chemistry as test field area for input of the sample remains uncovered by a housing material of the housing part, wherein the housing is configured such that at least one observation window is produced in the housing, wherein the test field area is optically monitorable through the observation window of the housing wherein the process is carried out such that the housing forms at least one chamber, wherein the test field area faces an interior space of the chamber.
A polyamide molding compound comprising the following components to or consisting of these components: 69 to 94.7 wt% of at least one amorphous copolyamide formed from the monomers to: 50 to 80 mol% of at least one acrylic aliphatic diamine having 6 to 10 carbon atoms; 20 to 50 mol% of at least one cycloaliphatic diamine having 6 to 36 carbon atoms; 40 to 80 mol% of at least one aromatic dicarboxylic acid; 20 to 60 mol% of at least one acrylic, aliphatic dicarboxylic acid having 8 to 16 carbon atoms, where the proportions of the monomers and are related to the sum of the diamines used and add up to 100 mol% in sum; and where the proportions of the monomers and are related to the sum of the dicarboxylic acids used and add up to 100 mol% in sum; 5 to 25 wt% of at least one partially crystalline polyamide selected from the group consisting of PA 612, PA 6/12, PA 516, PA 614, PA 616, PA 618, PA 1012, PA 1014, PA 1016, PA 1018, and mixtures hereof; and 0.3 to 6 wt% of at least one additive; wherein the quantity proportions of the components to add up to 100 wt% in sum. 69 to 94.7 wt% of at least one amorphous copolyamide formed from the monomers to: 50 to 80 mol% of at least one acrylic aliphatic diamine having 6 to 10 carbon atoms; 20 to 50 mol% of at least one cycloaliphatic diamine having 6 to 36 carbon atoms; 40 to 80 mol% of at least one aromatic dicarboxylic acid; 20 to 60 mol% of at least one acrylic, aliphatic dicarboxylic acid having 8 to 16 carbon atoms, where the proportions of the monomers and are related to the sum of the diamines used and add up to 100 mol% in sum; and where the proportions of the monomers and are related to the sum of the dicarboxylic acids used and add up to 100 mol% in sum; 50 to 80 mol% of at least one acrylic aliphatic diamine having 6 to 10 carbon atoms; 20 to 50 mol% of at least one cycloaliphatic diamine having 6 to 36 carbon atoms; 40 to 80 mol% of at least one aromatic dicarboxylic acid; 20 to 60 mol% of at least one acrylic, aliphatic dicarboxylic acid having 8 to 16 carbon atoms, 5 to 25 wt% of at least one partially crystalline polyamide selected from the group consisting of PA 612, PA 6/12, PA 516, PA 614, PA 616, PA 618, PA 1012, PA 1014, PA 1016, PA 1018, and mixtures hereof; and 0.3 to 6 wt% of at least one additive; wherein the quantity proportions of the components to add up to 100 wt% in sum.
A biological specimen observation apparatus for observing temporal change in a biological specimen, comprising: macro image acquisition means adapted to acquire macro images by capturing an image of a macro region of a broad range of the biological specimen using a first observation magnification rate with a first interval period (ΔT); biological change region extracting means adapted to extract a biological change region, which is a region where the biological specimen has changed by applying prescribed image analysis processing to at least one of the acquired macro images; micro image acquisition means adapted to acquire micro images by capturing an image of a micro region using a second observation magnification rate which is higher than the first observation magnification rate with a second interval period (Δt) characterized in that said micro region corresponds to said biological change region extracted by the biological change region extracting means, said apparatus further comprising micro observation point setting means adapted to register a micro observation point corresponding to the biological change region extracted by the biological change region extracting means; and judgment means adapted to judge whether or not biological change has continued in the biological change region at the micro observation point, from the acquired micro image; wherein the micro observation point setting means is adapted to update the registered micro observation point on the basis of a judgment result by the judgment means. macro image acquisition means adapted to acquire macro images by capturing an image of a macro region of a broad range of the biological specimen using a first observation magnification rate with a first interval period (ΔT); biological change region extracting means adapted to extract a biological change region, which is a region where the biological specimen has changed by applying prescribed image analysis processing to at least one of the acquired macro images; micro image acquisition means adapted to acquire micro images by capturing an image of a micro region using a second observation magnification rate which is higher than the first observation magnification rate with a second interval period (Δt) characterized in that said micro region corresponds to said biological change region extracted by the biological change region extracting means, said apparatus further comprising micro observation point setting means adapted to register a micro observation point corresponding to the biological change region extracted by the biological change region extracting means; and judgment means adapted to judge whether or not biological change has continued in the biological change region at the micro observation point, from the acquired micro image; wherein the micro observation point setting means is adapted to update the registered micro observation point on the basis of a judgment result by the judgment means.
A reading device for identifying a tag or an object adapted to be identified, said reading device comprising: a first reading element for reading a first set of identification features located in the tag or the object adapted to be identified, wherein the first reading element is a magneto-optical reading element adapted for reading magnetic features in the tag or object; and a second reading element for reading a second set of identification features located in the tag or the object adapted to be identified, wherein the second reading element is selected from the group consisting of a barcode scanner, a radio frequency identification tag reader, a character recognition reader, an optical image capturing system, a gaussmeter, a magnetometer, a fluorescence meter, a residumeter and a transponder; wherein the reading device is configured such that a first signal generated from reading the first set of identification features and a second signal generated from reading the second set of identification features are independently used to derive a first signature and a second signature for identifying the tag or object, wherein the magneto-optical reading element comprises at least one optical processing unit and at least one magneto-optical substrate; characterized in that the first reading element comprises an engagement element for positioning the magneto-optical substrate over an area of the first set of identification features, wherein the engagement element surrounds the magneto-optical substrate. a first reading element for reading a first set of identification features located in the tag or the object adapted to be identified, wherein the first reading element is a magneto-optical reading element adapted for reading magnetic features in the tag or object; and a second reading element for reading a second set of identification features located in the tag or the object adapted to be identified, wherein the second reading element is selected from the group consisting of a barcode scanner, a radio frequency identification tag reader, a character recognition reader, an optical image capturing system, a gaussmeter, a magnetometer, a fluorescence meter, a residumeter and a transponder; wherein the reading device is configured such that a first signal generated from reading the first set of identification features and a second signal generated from reading the second set of identification features are independently used to derive a first signature and a second signature for identifying the tag or object, wherein the magneto-optical reading element comprises at least one optical processing unit and at least one magneto-optical substrate; characterized in that the first reading element comprises an engagement element for positioning the magneto-optical substrate over an area of the first set of identification features, wherein the engagement element surrounds the magneto-optical substrate.
Screw nut having a sensor module for determining a prestressing force of a screw connection, wherein the sensor module comprises at least one deformation-detecting sensor, which is arranged on a main body of the screw nut, for detecting a deformation of the main body of the screw nut and comprises an RFID transponder unit, and wherein a printed circuit board of the sensor module, on which printed circuit board an antenna of the RFID transponder unit and an electronic circuit of the sensor module are formed and which printed circuit board is electrically conductively coupled to the at least one deformation-detecting sensor, is arranged on an end side of the main body, characterized in that the printed circuit board is of annular design, wherein a clear width of a passage opening in the printed circuit board is at least as large as a clear width of a screw opening in the main body.
A method of operating a vehicle door comprising the steps of: providing a door presenting signal; unlatching the door; detecting the motion associated with the unlatched door; pushing the unlatched door to an ajar position with a presenting actuator in response to the detected motion associated with the unlatched door, wherein the ajar position corresponds to an exterior surface of the unlatched door proud of the vehicle body line with the unlatched door disposed in a door opening to obstruct the door opening and prevent occupant egress or ingress; and mechanically holding the unlatched door in the ajar position. providing a door presenting signal; unlatching the door; detecting the motion associated with the unlatched door; pushing the unlatched door to an ajar position with a presenting actuator in response to the detected motion associated with the unlatched door, wherein the ajar position corresponds to an exterior surface of the unlatched door proud of the vehicle body line with the unlatched door disposed in a door opening to obstruct the door opening and prevent occupant egress or ingress; and mechanically holding the unlatched door in the ajar position.
A nickel recovery loss reduction method comprising the steps of: blowing a hydrogen sulfide gas into a sulfuric acid aqueous solution containing nickel and cobalt recovered through a leaching step, a solid-liquid separating step and a neutralizing step in a hydrometallurgical method based upon a high-temperature pressure leaching process for recovering nickel from nickel oxidized ores, carrying out a sulfurizing treatment in which a sulfurizing reaction is executed to generate sulfides containing nickel and a barren liquid, wherein sulfides containing nickel that have been recovered through the sulfurizing step are circulated and used again and the sulfides which have an average particle size of 55 μm or more obtained by classifying the sulfides in a liquid cyclone are added to the sulfuric acid aqueous solution as seed crystals. blowing a hydrogen sulfide gas into a sulfuric acid aqueous solution containing nickel and cobalt recovered through a leaching step, a solid-liquid separating step and a neutralizing step in a hydrometallurgical method based upon a high-temperature pressure leaching process for recovering nickel from nickel oxidized ores, carrying out a sulfurizing treatment in which a sulfurizing reaction is executed to generate sulfides containing nickel and a barren liquid, wherein sulfides containing nickel that have been recovered through the sulfurizing step are circulated and used again and the sulfides which have an average particle size of 55 μm or more obtained by classifying the sulfides in a liquid cyclone are added to the sulfuric acid aqueous solution as seed crystals.
A preventive or therapeutic pharmaceutical composition comprising as an active ingredient the protein of or: a protein comprising the amino acid sequence of SEQ ID NO: 2; or a protein comprising an amino acid sequence with at least 80% identity to SEQ ID NO: 2, or the DNA of or or a vector carrying said DNA: a DNA comprising the nucleotide sequence of SEQ ID NO: 1; or a DNA that hybridizes under stringent conditions with the nucleotide sequence of SEQ ID NO: 1, wherein the proteins of and induce adiponectin expression and the DNAs of and encode the proteins. a protein comprising the amino acid sequence of SEQ ID NO: 2; or a protein comprising an amino acid sequence with at least 80% identity to SEQ ID NO: 2, a DNA comprising the nucleotide sequence of SEQ ID NO: 1; or a DNA that hybridizes under stringent conditions with the nucleotide sequence of SEQ ID NO: 1,
A photostable sunscreen composition in microemuision format with dispersed phase droplets in the size range of 4 to 100 nm, the photostable sunscreen composition comprising: a. 0.1 % to 10 % by weight dibenzoylmethane or its derivative; b. 10 to 40% by weight an emulsifier; c. 5 to 40% by weight a co-emulsifier selected from the group consisting of C2 to C8 straight or branched chain alcohol, polyhydric alcohol and C5 to C8 low molecular weight fatty acid; d. 10 to 50% by weight of a hydrophobic liquid having a log P value at 25 degrees centigrade greater than 3 and a water solubility at 25 degrees centigrade less than 0.1 % by weight; and e. 10 to 50% by weight water, wherein said emulsifier is a nonionic surfactant; wherein the dibenzoylmethane derivative is selected from 4-tert-butyl-4'-methoxydibenzoylmethane, 2-methyldibenzoylmethane, 4-methyl-dibenzoylmethane, 4-isopropyldibenzoylmethane, 4-tert-butyldibenzoylmethane, 2, 4-dimethyldibenzoylmethane, 2, 5-dimethyldibenzoylmethane, 4, 4'-diisopropyl-dibenzoylmethane, 2-methyl-5-isopropyl-4'-methoxydibenzoylmethane, 2-methyl-5-tert-butyl-4-methoxydibenzoylmethane,2, 4-dimethyl-4'-methoxydibenzoylmethane or 2, 6-dimethyl-4-tert-butyl-4'-methoxy-dibenzoylmethane. a. 0.1 % to 10 % by weight dibenzoylmethane or its derivative; b. 10 to 40% by weight an emulsifier; c. 5 to 40% by weight a co-emulsifier selected from the group consisting of C2 to C8 straight or branched chain alcohol, polyhydric alcohol and C5 to C8 low molecular weight fatty acid; d. 10 to 50% by weight of a hydrophobic liquid having a log P value at 25 degrees centigrade greater than 3 and a water solubility at 25 degrees centigrade less than 0.1 % by weight; and e. 10 to 50% by weight water,
A composition for making a polyurethane foam, said composition comprising at least: (a) a polyfunctional isocyanate; (b) an isocyanate reactive composition; and (c) a compound of the formula: or wherein R1 is selected from hydrogen, hydroxyl, or an unsubstituted or substituted C 1 -C 35 alkyl, C 2 -C 35 alkenyl, aryl, alkylaryl, or C 1 -C 35 alkoxy group, R2 is selected from a bond, or an unsubstituted or substituted aryl, C 2 -C 35 alkenyl, alkylaryl, C 1 -C 35 alkoxy, or C 1 -C 35 alkyl group, A is an ion with positive charge, wherein the compound (c) is present by weight percentage in the composition in an amount ranging from 0.001 to 2 based on the total weight of the composition and wherein the NCO index of the composition is in the range of from 0.6 to 1.5, preferably from 0.8 to 1.3. (a) a polyfunctional isocyanate; (b) an isocyanate reactive composition; and (c) a compound of the formula: or R1 is selected from hydrogen, hydroxyl, or an unsubstituted or substituted C 1 -C 35 alkyl, C 2 -C 35 alkenyl, aryl, alkylaryl, or C 1 -C 35 alkoxy group, R2 is selected from a bond, or an unsubstituted or substituted aryl, C 2 -C 35 alkenyl, alkylaryl, C 1 -C 35 alkoxy, or C 1 -C 35 alkyl group, A is an ion with positive charge,
An avermectin compound for use in topical application on an affected area of the skin for treating a superficial or partial thickness burn caused by heat, or by UV or laser radiation, wherein said avermectin compound is selected from the group consisting of ivermectin, avermectin A 1a, avermectin A 1b, avermectin A 2a, avermectin A 2b, avermectin B 1a, avermectin B 1b, avermectin B 2a, avermectin B 2b, or a compound having the following molecular structure: wherein R is a 4'-(alpha-L-oleandrosyl)-alpha-L-oleandrose group of the following structure: wherein the broken line indicates a single or double bond; R 1 is hydroxy and is present only when said broken line indicates a single bond; R 2 is isopropyl or sec-butyl; and R 3 is methoxy or hydroxyl.
A hybrid vehicle comprising: an engine; a driving motor/generator connected to an output shaft of the engine; a connection unit disposed between the engine and the driving motor/generator to separate the engine from the driving motor/generator when the engine is stopped and to connect the engine to the driving motor/generator when the engine is running; a manual transmission connected to the driving motor/generator, for directly varying the gear ratio without using an engine clutch, according to a driving speed and a torque generated by the driving motor/generator and/or the engine; a position sensor for detecting the moving direction of the manual gearshift lever; characterized in a central control unit connected to the engine, the driving motor/generator, the connection unit, and the manual transmission, for in order to perform a gearshift of the manual transmission, separating the connection unit disposed between the engine and the driving motor/generator when the vehicle is stopped or driven at a speed lower than the preset speed, or connecting the connection unit when the vehicle is driven at the preset speed or higher, and controlling the driving motor/generator and/or the engine according to the detected moving direction of the manual gearshift lever to adjust the speed of the input shaft of the manual transmission. an engine; a driving motor/generator connected to an output shaft of the engine; a connection unit disposed between the engine and the driving motor/generator to separate the engine from the driving motor/generator when the engine is stopped and to connect the engine to the driving motor/generator when the engine is running; a manual transmission connected to the driving motor/generator, for directly varying the gear ratio without using an engine clutch, according to a driving speed and a torque generated by the driving motor/generator and/or the engine; a position sensor for detecting the moving direction of the manual gearshift lever; characterized in a central control unit connected to the engine, the driving motor/generator, the connection unit, and the manual transmission, for in order to perform a gearshift of the manual transmission, separating the connection unit disposed between the engine and the driving motor/generator when the vehicle is stopped or driven at a speed lower than the preset speed, or connecting the connection unit when the vehicle is driven at the preset speed or higher, and controlling the driving motor/generator and/or the engine according to the detected moving direction of the manual gearshift lever to adjust the speed of the input shaft of the manual transmission.