A multilayer bottle comprising a barrel portion including an outermost layer, an innermost layer and at least one barrier layer interposed between the outermost layer and the innermost layer, wherein the outermost layer and the innermost layer are each made mainly of a thermoplastic polyester resin obtained by polymerizing a dicarboxylic acid component containing 80 mol% or more of terephthalic acid with a diol component containing 80 mol% or more of ethylene glycol; and the bottle is provided on a side wall surface thereof with at least one concave portion and/or at least one convex portion, characterized in that OTR ≤ 0.2 cc ⋅ mm / m 2 ⋅ day ⋅ atm where OTR represents an average oxygen transmission rate of the barrier layer of the barrel portion as measured at a temperature of 23°C and a relative humidity of 60%; 20 ≤ Average degree of orientation of barrier layer of barrel portion ≤ 45, where the degree of orientation represents a value calculated from refractive indices of the barrier layer as measured at 23°C using an Abbe refractometer according to the following formula: Degree of orientation = n x + n y / 2 − n z × 1000 where n(x) represents a refractive index of the barrier layer in a height direction of the bottle; n(y) represents a refractive index of the barrier layer in a circumferential direction of the bottle; and n(z) represents a refractive index of the barrier layer in a thickness direction thereof; 0 ≤ b / a × 100 ≤ 200 where "a" represents an average thickness (μm) of the barrier layer of the barrel portion; and "b" represents an average thickness (μm) of the barrier layer of a bottom portion of the bottle, wherein, in the above respective formulae, the bottom portion is defined as a portion extending from a ground portion of the bottle to a position corresponding to 20% of a height between the ground portion and an opening portion of the bottle; the barrel portion is defined as a portion except for the ground portion which has an outer diameter corresponding to 80% or more of a maximum outer diameter of the ground portion; and the ground portion is defined as a portion contacting with a floor when the bottle is vertically placed thereon; the concave portion satisfies the following requirements to at the same time: an angle (Aa) between a tangential line of a bottom of the concave portion and a tangential line of a side face of the concave portion being 100° or more; an angle (Ab) between a tangential line of the side wall surface of the bottle and a tangential line of the side face of the concave portion being 80° or less; and a depth (Ac) of the concave portion being 10% or less of an outer diameter of a portion including the concave portion; and/or the convex portion satisfies the following requirements to at the same time: an angle (Ba) between a tangential line of the side wall surface of the bottle and a tangential line of a side face of the convex portion being 100° or more; an angle (Bb) between a tangential line of an apex of the convex portion and a tangential line of the side face of the convex portion being 80° or less; and a height (Bc) of the convex portion being 10% or less of an outer diameter of a portion including the convex portion. an angle (Aa) between a tangential line of a bottom of the concave portion and a tangential line of a side face of the concave portion being 100° or more; an angle (Ab) between a tangential line of the side wall surface of the bottle and a tangential line of the side face of the concave portion being 80° or less; and a depth (Ac) of the concave portion being 10% or less of an outer diameter of a portion including the concave portion; and/or an angle (Ba) between a tangential line of the side wall surface of the bottle and a tangential line of a side face of the convex portion being 100° or more; an angle (Bb) between a tangential line of an apex of the convex portion and a tangential line of the side face of the convex portion being 80° or less; and a height (Bc) of the convex portion being 10% or less of an outer diameter of a portion including the convex portion.