A benzoxazine oxazolidinone compound of general formula, an optical isomer thereof or a pharmaceutically acceptable salt thereof, wherein, R 1 is hydroxyl,, wherein, R 6 and R 7 are each independently H, C 1 -C 4 straight-chain or branched alkyl, or benzyl; R 8 is H, C 1 -C 4 straight-chain or branched alkyl, or benzyl; n is 0 or 1; R 2 is absent or C 1 -C 4 straight-chain or branched alkyl; R 3 is halogen; -CN; C 1 -C 6 straight-chain or branched alkyl substituted by one or more groups selected from the group consisting of hydroxyl, oxo, halogen, amino, C 3 -C 6 cycloalkyl and substituted or unsubstituted 5- or 6- membered aromatic heterocyclic group containing at least one heteroatom selected from N, O or S; 3- to 6- membered cylcoalkyl, which is unsubstituted or substituted by amino, C 1 -C 4 straight-chain or branched alkyl or hydroxyl; the substituent for said substituted 5- or 6-membered aromatic heterocyclic group containing at least one heteroatom selected from N, O or S is C 1 -C 4 straight-chain or branched alkyl; Z is C, N or O; R 9 represents one or more substituents, which are the same or different, and which are each independently selected from the group consisting of H; C 1 -C 4 straight-chain or branched alkyl; benzyl; C 1 -C 4 straight-chain-chain or branched alkyl substituted by one or more groups selected from the group consisting of hydroxyl, oxo and amino; and Y is C, N or O; R 10 represents one or more substituents, which are each independently selected from the group consisting of H, hydroxyl, oxo and C 1 -C 4 straight-chain or branched alkyl; R 12 represents one or more substituents, which are each selected from the group consisting of H, hydroxyl, halogen or C 1 -C 4 straight-chain or branched alkyl. R 1 is hydroxyl,, wherein, R 6 and R 7 are each independently H, C 1 -C 4 straight-chain or branched alkyl, or benzyl; R 8 is H, C 1 -C 4 straight-chain or branched alkyl, or benzyl; n is 0 or 1; R 6 and R 7 are each independently H, C 1 -C 4 straight-chain or branched alkyl, or benzyl; R 8 is H, C 1 -C 4 straight-chain or branched alkyl, or benzyl; n is 0 or 1; R 2 is absent or C 1 -C 4 straight-chain or branched alkyl; R 3 is halogen; -CN; C 1 -C 6 straight-chain or branched alkyl substituted by one or more groups selected from the group consisting of hydroxyl, oxo, halogen, amino, C 3 -C 6 cycloalkyl and substituted or unsubstituted 5- or 6- membered aromatic heterocyclic group containing at least one heteroatom selected from N, O or S; 3- to 6- membered cylcoalkyl, which is unsubstituted or substituted by amino, C 1 -C 4 straight-chain or branched alkyl or hydroxyl; the substituent for said substituted 5- or 6-membered aromatic heterocyclic group containing at least one heteroatom selected from N, O or S is C 1 -C 4 straight-chain or branched alkyl; Z is C, N or O; R 9 represents one or more substituents, which are the same or different, and which are each independently selected from the group consisting of H; C 1 -C 4 straight-chain or branched alkyl; benzyl; C 1 -C 4 straight-chain-chain or branched alkyl substituted by one or more groups selected from the group consisting of hydroxyl, oxo and amino; and Y is C, N or O; R 10 represents one or more substituents, which are each independently selected from the group consisting of H, hydroxyl, oxo and C 1 -C 4 straight-chain or branched alkyl; R 12 represents one or more substituents, which are each selected from the group consisting of H, hydroxyl, halogen or C 1 -C 4 straight-chain or branched alkyl.