mhurhangee/ep-ind-claims huggingface dataset:
An isolated antibody or antigen-binding fragment thereof, capable of specifically binding to an epitope in the stem region of the hemagglutinin protein of influenza A virus subtypes of phylogenetic group 1 and influenza A virus subtypes of phylogenetic group 2 subtypes, and capable of neutralizing at least one or more group 1 influenza A virus subtypes, selected from the group consisting of influenza A viruses comprising HA of the H1, H2, H5, H6, H8, H9 and H11 subtype, and at least one or more group 2 influenza A virus subtypes, selected from the group consisting of influenza A viruses comprising HA of the H3, H4, H7, and H10 subtype, characterized in that the antibody or antigen-binding fragment thereof is also capable of specifically binding to the hemagglutinin protein of influenza B virus subtypes.
A human beta cell that expresses or overexpresses a human fugetactic agent in an amount sufficient to render said beta cell resistant to human immune cells, wherein said beta cell is capable of expressing insulin and incapable of cell division.
A composition comprising: a compound of formula: or a pharmaceutically acceptable salt thereof, wherein: Q is piperazine-1,4-diyl or substituted piperazine-1,4-diyl wherein the piperazine is substituted with one to eight substituents in the 2, 3, 5, or 6 positions and wherein the substituents are independently selected from the group consisting of (C 1 to C 6)alkyl, aryl, aryl(C 1 to C 6)alkyl, C OH, and C O(C 1 to C 6)alkyl; A 1 and A 1 ' are each independently N or CR 6; A 2 and A 2 ' are each independently N or CR 7; A 3 is NR 8; A 3 ' is NR 8, O, or S; A 4 and A 4 ' are each independently N or CR 9; A 5 and A 5 ' are each independently N or CR 10; A 6 and A 6 ' are each independently N or CR 11; and R 1, R 1', R 2, R 2', R 3, R 3', R 4, R 4', R 6, R 7, R 8, R 9, R 10, and R 11, if present, are in each instance independently selected from the group consisting of hydrogen, alkyl, halo, trifluoromethyl, dialkylamino wherein each alkyl is the same or different, -NH 2, alkylamino, and arylalkyl; and a pharmaceutically acceptable diluent or carrier. a compound of formula: or a pharmaceutically acceptable salt thereof, wherein: Q is piperazine-1,4-diyl or substituted piperazine-1,4-diyl wherein the piperazine is substituted with one to eight substituents in the 2, 3, 5, or 6 positions and wherein the substituents are independently selected from the group consisting of (C 1 to C 6)alkyl, aryl, aryl(C 1 to C 6)alkyl, C OH, and C O(C 1 to C 6)alkyl; A 1 and A 1 ' are each independently N or CR 6; A 2 and A 2 ' are each independently N or CR 7; A 3 is NR 8; A 3 ' is NR 8, O, or S; A 4 and A 4 ' are each independently N or CR 9; A 5 and A 5 ' are each independently N or CR 10; A 6 and A 6 ' are each independently N or CR 11; and R 1, R 1', R 2, R 2', R 3, R 3', R 4, R 4', R 6, R 7, R 8, R 9, R 10, and R 11, if present, are in each instance independently selected from the group consisting of hydrogen, alkyl, halo, trifluoromethyl, dialkylamino wherein each alkyl is the same or different, -NH 2, alkylamino, and arylalkyl; and Q is piperazine-1,4-diyl or substituted piperazine-1,4-diyl wherein the piperazine is substituted with one to eight substituents in the 2, 3, 5, or 6 positions and wherein the substituents are independently selected from the group consisting of (C 1 to C 6)alkyl, aryl, aryl(C 1 to C 6)alkyl, C OH, and C O(C 1 to C 6)alkyl; A 1 and A 1 ' are each independently N or CR 6; A 2 and A 2 ' are each independently N or CR 7; A 3 is NR 8; A 3 ' is NR 8, O, or S; A 4 and A 4 ' are each independently N or CR 9; A 5 and A 5 ' are each independently N or CR 10; A 6 and A 6 ' are each independently N or CR 11; and R 1, R 1', R 2, R 2', R 3, R 3', R 4, R 4', R 6, R 7, R 8, R 9, R 10, and R 11, if present, are in each instance independently selected from the group consisting of hydrogen, alkyl, halo, trifluoromethyl, dialkylamino wherein each alkyl is the same or different, -NH 2, alkylamino, and arylalkyl; and a pharmaceutically acceptable diluent or carrier.
Rotor for a rotating electric machine, comprising: - a rotor shaft, - a rotor winding arranged for conjoint rotation on the rotor shaft, - a slip ring body arranged on an axial end of the rotor shaft, wherein an end face of the slip ring body is formed on an axial end of the slip ring body opposite the rotor winding, and - a driver unit for a rotary encoder which is arranged non-rotatably in relation to the rotor and which is fastened to the end face of the slip ring body and/or to the axial end of the rotor shaft, - wherein the slip ring body has connection adapters which project axially beyond the end face of the slip ring body and to which line ends of the rotor winding are connected, and - wherein the driver unit is electrically insulated from the connection adapters at least in a partial region which is arranged at the same level as the connection adapters in the direction of an axis of rotation of the rotor shaft, characterized - by a centrifugal force support ring having a through-opening, which is arranged on the end face of the slip ring body in such a way that the connection adapters and the driver unit are arranged at least in part in the through-opening of the centrifugal force support ring. - a rotor shaft, - a rotor winding arranged for conjoint rotation on the rotor shaft, - a slip ring body arranged on an axial end of the rotor shaft, wherein an end face of the slip ring body is formed on an axial end of the slip ring body opposite the rotor winding, and - a driver unit for a rotary encoder which is arranged non-rotatably in relation to the rotor and which is fastened to the end face of the slip ring body and/or to the axial end of the rotor shaft, - wherein the slip ring body has connection adapters which project axially beyond the end face of the slip ring body and to which line ends of the rotor winding are connected, and - wherein the driver unit is electrically insulated from the connection adapters at least in a partial region which is arranged at the same level as the connection adapters in the direction of an axis of rotation of the rotor shaft, characterized - by a centrifugal force support ring having a through-opening, which is arranged on the end face of the slip ring body in such a way that the connection adapters and the driver unit are arranged at least in part in the through-opening of the centrifugal force support ring.
A multi-nozzle system for dosing a powdery substance, the system comprising a tank of the powdery substance, the bottom of the tank being formed by a horizontal tank plate comprising at least one row of at least two openings arranged along a first longitudinal axis, the system further comprising a horizontal measuring plate located directly under the tank plate and a horizontal dosing plate located below the measuring plate, the tank plate and the dosing plate being immovable with respect to the tank, and the measuring plate being horizontally translatable with respect to the tank back-and-forth along the first longitudinal axis; the measuring plate and the dosing plate comprising openings respectively and, the number of the openings in each of the measuring plate and the dosing plate corresponding to the number of the openings of the tank plate, and the size and shape of the openings and corresponding to the size and shape of the openings, characterized in that between the measuring plate and the dosing plate an intermediate plate is located, the intermediate plate being horizontally translatable back-and-forth along the first longitudinal axis and the intermediate plate being in top-side contact with the measuring plate and in a bottom-side contact with the dosing plate, the intermediate plate comprising openings the number, the size and the shape of which correspond to the number, the size and the shape of the openings of the tank plate, and in that the measuring plate is translatable between a position in which its openings coincide with the openings of the tank plate and a position in which its openings are not in communication with the openings of the tank plate, and the intermediate plate is translatable between a position in which its openings coincide with the openings of at least one plate of a pair of plates comprising the dosing plate and the measuring plate and a position in which its openings are not in communication with the openings of the other plates (3, 4, 6).
Method for calibrating a head system of a power radiation source of an additive manufacturing apparatus in which, to determine a correction to be applied to the commands of said system, the following steps are implemented: - positioning in the additive manufacturing apparatus a calibration plate comprising a plurality of reference marks, - commanding the source to mark on the calibration plate at least one calibration pattern formed of a plurality of impact points, - acquiring at least one image of said calibration pattern and of at least one reference mark, - determining at least one corrected command depending on the one or more images thus obtained, characterized in that the step of determining a corrected command determines, in an acquired image, the distribution of the diameters of the impact points of the calibration pattern that appears in said image, said corrected command being dependent on said distribution of the diameters of the impact points and being a focus command. - positioning in the additive manufacturing apparatus a calibration plate comprising a plurality of reference marks, - commanding the source to mark on the calibration plate at least one calibration pattern formed of a plurality of impact points, - acquiring at least one image of said calibration pattern and of at least one reference mark, - determining at least one corrected command depending on the one or more images thus obtained, characterized in that the step of determining a corrected command determines, in an acquired image, the distribution of the diameters of the impact points of the calibration pattern that appears in said image, said corrected command being dependent on said distribution of the diameters of the impact points and being a focus command.
An integrated switch for a pneumatic detector to indicate pressure changes in an environment, the integrated switch comprising: a housing with a cavity between a first retainer portion and a second retainer portion; a first diaphragm held in the cavity of the housing to indicate fault conditions; and a second diaphragm held in the cavity of the housing to indicate alarm conditions, characterised in that the integrated switch further comprises: a contact pin held in the first retainer portion; and a pressure tube connected to the cavity and running through the second retainer portion, wherein the first diaphragm is held in the cavity near the second retainer portion and the second diaphragm is held in the cavity near the first retainer portion. a housing with a cavity between a first retainer portion and a second retainer portion; a first diaphragm held in the cavity of the housing to indicate fault conditions; and a second diaphragm held in the cavity of the housing to indicate alarm conditions, characterised in that the integrated switch further comprises: a contact pin held in the first retainer portion; and a pressure tube connected to the cavity and running through the second retainer portion, wherein the first diaphragm is held in the cavity near the second retainer portion and the second diaphragm is held in the cavity near the first retainer portion. a contact pin held in the first retainer portion; and a pressure tube connected to the cavity and running through the second retainer portion, wherein the first diaphragm is held in the cavity near the second retainer portion and the second diaphragm is held in the cavity near the first retainer portion.
Omni-wheel comprising two rolling body carriers which are rotatable about a wheel axis and on the circumference of which carriers rolling bodies, on which the omni-wheel rolls, are rotatably mounted, the rolling body axes of which bodies are arranged at a rolling body angle relative to imaginary parallel lines with respect to the wheel axis, characterized in that the rolling body carriers have angularly flexible rolling body receptacles for the rolling bodies.
A method for generating power headroom information by a terminal in a mobile communication system, the method comprising: determining (515, 520) whether a path loss has changed more than a threshold and whether the terminal has an allocated uplink transmission resource; if the path loss has changed more than the threshold and the terminal has an allocated uplink transmission resource, generating (525,530) the power headroom information and an uplink packet comprising the power headroom information by using the allocated uplink transmission resource. determining (515, 520) whether a path loss has changed more than a threshold and whether the terminal has an allocated uplink transmission resource; if the path loss has changed more than the threshold and the terminal has an allocated uplink transmission resource, generating (525,530) the power headroom information and an uplink packet comprising the power headroom information by using the allocated uplink transmission resource.
A semiconductor laser module, wherein the module comprises: a direct-output type semiconductor laser light source, and a light beam shaping device disposed in the light-exit direction of the direct-output type semiconductor laser light source; wherein the light beam shaping device comprises a light reflection component configured to homogenize the laser beam outputted by the direct-output type semiconductor laser light source, wherein the light reflection component is a hollow component; wherein the inner wall of the light reflection component is configured to realize that the laser beam is reflected on the inner wall of the light reflection component, to form a uniform light path; wherein the module further comprises a cooling structure disposed on the periphery of the light reflection component; wherein the cooling structure comprises a cooling frame, a thermoelectric cooler and a heat dissipation block, wherein a contact window used for contacting skin and cooling the skin is disposed at the cooling frame, wherein the cooling frame is used for cooling the contact window; wherein a contact sensor is disposed at the contact window, wherein the contact sensor is configured to sense the fit degree between the contact window and the skin.
Assembly of parts comprising: - a first part provided with a vertical conduit having a lower part and an upper part, - a second part resting on an upper face of the first part and provided with a hole receiving the upper part of the conduit, - a third part having a hole located below and in line with the conduit, and - a fixing rod extending successively into the hole of the second part, into the conduit of the first part and into the hole of the third part, the fastening rod having an upper end provided with a stop resting on an upper face of the second part, and in that the second part has, in the hole, a shoulder against which the upper part of the conduit is folded down so as to clamp the second part between the foldeddown upper part of the conduit and the upper face to fix the second part to the first part. - a first part provided with a vertical conduit having a lower part and an upper part, - a second part resting on an upper face of the first part and provided with a hole receiving the upper part of the conduit, - a third part having a hole located below and in line with the conduit, and - a fixing rod extending successively into the hole of the second part, into the conduit of the first part and into the hole of the third part, the fastening rod having an upper end provided with a stop resting on an upper face of the second part,
A method for establishing a label switched path, LSP, wherein the method comprises: allocating, by a proxy node device, a first label for a destination node device, wherein the proxy node device is an intermediary node device between an entry node device and the destination node device; generating, by the proxy node device, a label mapping message, wherein the label mapping message carries the first label, an address of the destination node device and an address of the proxy node device; sending, by the proxy node device, the label mapping message to an upstream node device of the proxy node device to initiate establishment a first LSP from the entry node device to the proxy node device, wherein during the establishment of the first LSP, the address of the proxy node device is used by the upstream node device to match a routing table, and allocate a second label for the destination node device when a route reaching the proxy node device is matched; and stitching, by the proxy node device, the first LSP with a second LSP to form a third LSP from the entry node device to the destination node device, wherein the second LSP is an LSP established between the proxy node device and the destination node device, and the first LSP and the second LSP are LSPs of different protocol types. allocating, by a proxy node device, a first label for a destination node device, wherein the proxy node device is an intermediary node device between an entry node device and the destination node device; generating, by the proxy node device, a label mapping message, wherein the label mapping message carries the first label, an address of the destination node device and an address of the proxy node device; sending, by the proxy node device, the label mapping message to an upstream node device of the proxy node device to initiate establishment a first LSP from the entry node device to the proxy node device, wherein during the establishment of the first LSP, the address of the proxy node device is used by the upstream node device to match a routing table, and allocate a second label for the destination node device when a route reaching the proxy node device is matched; and stitching, by the proxy node device, the first LSP with a second LSP to form a third LSP from the entry node device to the destination node device, wherein the second LSP is an LSP established between the proxy node device and the destination node device, and the first LSP and the second LSP are LSPs of different protocol types.
Threshold for a sliding door, in particular a lifting-sliding door, having a strip-shaped base body (2, 2') made of a hard foam material, on the upper side of which a cover having at least one running track for the sliding door is arranged, wherein the cover is of single-wall design without cavities at least in the region of the track and rests positively against the upper side of the base body (2, 2'), characterized in that the base body (2, 2') has a plurality of sections (20-24; 20'-24') made of materials with different strength and an area below the at least one track has a higher strength than an area below a profile for the step protection.
A release device for releasing a medical implant from an insertion device, in which the implant can be released by a relative movement between a first and a second insertion element (10, 20), wherein the insertion device has a proximal end, which faces the user during use, and a distal end, which is distanced from the user during use, wherein, between the proximal and the distal end (202, 204), a shortening region is provided, in which, when generating a targeted relative movement between the first and the second insertion element (10, 20) of the insertion device, a length of at least one of the insertion elements between the proximal end and the distal end (202, 204) can be shortened, characterised in that the insertion element is shortened by folding.
Toilet cleaning brush with a base body, which has at least one closable liquid container for a cleaning liquid, whereby a manually actuable liquid valve is releasably arranged on the outlet opening of the liquid container and a brush head is releasably arranged on the base body, whereby the brush head is fastened to the base body by means of a click mechanism, the liquid container has a chamber, a liquid valve is arranged on the lower end of the liquid container, the liquid valve is a spring-loaded ball valve, which can be opened in the cleaning state by means of a manually actuable valve linkage, and the ball valve is closed in a liquid-tight manner in the idle state by the spring preload of a valve spring.
A nanoscale magnetic resonance imaging system for determining a spatial configuration of multiple nuclei, the system comprising: a substrate containing an electron-spin probe near a surface of the substrate; a first signal generator to generate a first signal; and a readout module to determine the phase of the electron-spin probe; characterised in that the electron-spin probe is configured to generate a spatially varying magnetic field (110, 112) such that each of the multiple nuclei is resonant at a respective resonance frequency defined by the magnetic field at a location of that nucleus; the first signal generator is configured to generate the first signal at a first signal frequency such that, as a result of dipole-dipole interaction between the electron-spin probe and a subset of the multiple nuclei that are resonant at the first signal frequency, a phase of the electron-spin probe is indicative of a number of nuclei that are resonant at the first signal frequency; the first frequency is between an upper frequency set by the value of the interaction at the surface of the substrate, immediately below the multiple nuclei, and a lower frequency that is no greater than the minimal coupling experienced by the uppermost nuclei; the imaging system further comprises a second signal generator to generate a second signal that decouples the multiple nuclei from each other to reduce interaction between the nuclei; and the readout module is configured to determine the spatial configuration of the multiple nuclei based on the phase of the electron-spin probe. a substrate containing an electron-spin probe near a surface of the substrate; a first signal generator to generate a first signal; and a readout module to determine the phase of the electron-spin probe; characterised in that the electron-spin probe is configured to generate a spatially varying magnetic field (110, 112) such that each of the multiple nuclei is resonant at a respective resonance frequency defined by the magnetic field at a location of that nucleus; the first signal generator is configured to generate the first signal at a first signal frequency such that, as a result of dipole-dipole interaction between the electron-spin probe and a subset of the multiple nuclei that are resonant at the first signal frequency, a phase of the electron-spin probe is indicative of a number of nuclei that are resonant at the first signal frequency; the first frequency is between an upper frequency set by the value of the interaction at the surface of the substrate, immediately below the multiple nuclei, and a lower frequency that is no greater than the minimal coupling experienced by the uppermost nuclei; the imaging system further comprises a second signal generator to generate a second signal that decouples the multiple nuclei from each other to reduce interaction between the nuclei; and the readout module is configured to determine the spatial configuration of the multiple nuclei based on the phase of the electron-spin probe.