mhurhangee/ep-ind-claims huggingface dataset:
A computerized image registration process, comprising: performing a line-based, tissue-matching image registration process to globally align a first image and a second image to a common grid, wherein the first image is a digital image of a tissue section and the second image is a digital image of an adjacent tissue section, wherein the first digital image is derived from an image obtained using a stain and an imaging mode, and the second digital image is derived from an image obtained using a different stain, a different imaging mode, or both as compared to the first digital image, wherein the line-based, tissue matching image registration method comprises a coarse registration mode comprising: generating a first foreground image having a boundary of the tissue from the first digital image and generating a second foreground image having a boundary of the tissue from the second digital image; computing a first set of line-based features from the boundary of the first foreground image and computing a second set of line-based features from the boundary of the second foreground image, wherein computing the first set of line-based features and computing the second set of line-based features comprises - breaking each foreground image into windowed regions, - identifying the windowed regions that lie along the boundary of the foreground image, - computing a best fitted line segment for each windowed boundary region, - computing a line segment model for those windowed boundary regions for which more than half of the boundary points contained within the windowed boundary region are close to the best fitted line segment, and - rejecting the windowed boundary regions for which half or less than half of the boundary points contained within the windowed boundary region are close to the best fitted line segment; computing global transformation parameters between the first set of line-based features and the second set of line-based features; and, globally aligning the first digital image with the second digital image based on the global transformation parameters. - breaking each foreground image into windowed regions, - identifying the windowed regions that lie along the boundary of the foreground image, - computing a best fitted line segment for each windowed boundary region, - computing a line segment model for those windowed boundary regions for which more than half of the boundary points contained within the windowed boundary region are close to the best fitted line segment, and - rejecting the windowed boundary regions for which half or less than half of the boundary points contained within the windowed boundary region are close to the best fitted line segment;
A non-naturally occurring or engineered composition for use in therapy, by manipulation of first and second target sequence on opposite strands of a DNA duplex in a genomic locus of interest in a cell by promoting homology directed repair, wherein the composition comprises: I. a first CRISPR-Cas system chimeric RNA (chiRNA) polynucleotide sequence, wherein the first polynucleotide sequence comprises: (a) a first guide sequence capable of hybridizing to the first target sequence, (b) a first tracr mate sequence, and (c) a first tracr sequence, II. a second CRISPR-Cas system chiRNA polynucleotide sequence, wherein the second polynucleotide sequence comprises: (a) a second guide sequence capable of hybridizing to the second target sequence, (b) a second tracr mate sequence, and (c) a second tracr sequence, III. a Type II Cas9 enzyme or a polynucleotide sequence encoding it, wherein the Cas9 enzyme is a SpCas9 protein comprising the mutation N863A, or an ortholog thereof having a mutation corresponding to SpCas9N863A, comprising zero, or at least one or two or more nuclear localization sequences, and IV. a repair template comprising a synthesized or engineered single-stranded oligonucleotide, wherein (a), (b) and (c) are arranged in a 5' to 3' orientation, wherein the polynucleotide sequence encoding the Cas9 enzyme is DNA or RNA, wherein the first guide sequence directs cleavage of one strand of the DNA duplex near the first target sequence and the second guide sequence directs cleavage of the other strand near the second target sequence resulting in 3' overhangs, and wherein the repair template is introduced into the DNA duplex. I. a first CRISPR-Cas system chimeric RNA (chiRNA) polynucleotide sequence, wherein the first polynucleotide sequence comprises: (a) a first guide sequence capable of hybridizing to the first target sequence, (b) a first tracr mate sequence, and (c) a first tracr sequence, (a) a first guide sequence capable of hybridizing to the first target sequence, (b) a first tracr mate sequence, and (c) a first tracr sequence, II. a second CRISPR-Cas system chiRNA polynucleotide sequence, wherein the second polynucleotide sequence comprises: (a) a second guide sequence capable of hybridizing to the second target sequence, (b) a second tracr mate sequence, and (c) a second tracr sequence, (a) a second guide sequence capable of hybridizing to the second target sequence, (b) a second tracr mate sequence, and (c) a second tracr sequence, III. a Type II Cas9 enzyme or a polynucleotide sequence encoding it, wherein the Cas9 enzyme is a SpCas9 protein comprising the mutation N863A, or an ortholog thereof having a mutation corresponding to SpCas9N863A, comprising zero, or at least one or two or more nuclear localization sequences, and IV. a repair template comprising a synthesized or engineered single-stranded oligonucleotide,
A vortex cleaner comprising a bottom diluter duct, the bottom diluter duct comprising at least - a flow channel, - a dilution water inlet for supplying dilution water to the flow channel, and - an outlet for discharging dilution water from the bottom diluter duct into the vortex cleaner, wherein the bottom diluter duct also comprises a means for controlling the flow of dilution water, arranged to be movable between a first and a second position, characterized in that in the first position the outlet is closed and in the second position the outlet is open, wherein the opening of the outlet is arranged to take place as a function of the ratio between the inlet pressure of dilution water and the pressure effective on said means for controlling the flow of dilution water in the vortex cleaner, wherein the pressure is generated in a separation cone of the vortex cleaner. - a flow channel, - a dilution water inlet for supplying dilution water to the flow channel, and - an outlet for discharging dilution water from the bottom diluter duct into the vortex cleaner, wherein
A method for use in a wireless device, the method comprising: receiving (110, 602) a release message from a network node operating in a network, wherein the release message comprises a first release token and an instruction to release a radio resource control, RRC, connection for supporting Control Plane Cellular Internet-of-Things, CP-CloT, or Data over Non Access Stratum, DoNAS, functionality; computing a second release token based at least in part on an algorithm agreed between the wireless device and the network; determining (112, 604) whether the first release token passes verification, wherein the first release token passes verification if it matches the computed second release token; and determining (114, 606) an action to perform based on whether the first release token passes verification; wherein, in response to a determination that the first release token passes verification, the action comprises releasing the RRC connection. receiving (110, 602) a release message from a network node operating in a network, wherein the release message comprises a first release token and an instruction to release a radio resource control, RRC, connection for supporting Control Plane Cellular Internet-of-Things, CP-CloT, or Data over Non Access Stratum, DoNAS, functionality; computing a second release token based at least in part on an algorithm agreed between the wireless device and the network; determining (112, 604) whether the first release token passes verification, wherein the first release token passes verification if it matches the computed second release token; and determining (114, 606) an action to perform based on whether the first release token passes verification; wherein, in response to a determination that the first release token passes verification, the action comprises releasing the RRC connection.
A method for tracking the positions of multiple electrodes disposed on an inflatable balloon fitted at a distal end of a catheter, comprising: in a processor, receiving position signals from, and generated by, (i) the multiple electrodes, and (ii) first and second electrodes (52a, 52b) fitted on a shaft of the catheter, on either side of the balloon, wherein the positions signals are indicative of the positions of (i) the multiple electrodes, and (ii) the first and second electrodes (52a, 52b), respectively; and calculating the positions of the multiple electrodes disposed on the balloon, based on the received position signals and on a known distance between the first and second electrodes (52a, 52b), wherein calculating the positions of the multiple electrodes comprises scaling the positions of the multiple electrodes based on the known distance between the first and second electrodes (52a, 52b) and the received position signals from the first and second electrodes (52a, 52b). in a processor, receiving position signals from, and generated by, (i) the multiple electrodes, and (ii) first and second electrodes (52a, 52b) fitted on a shaft of the catheter, on either side of the balloon, wherein the positions signals are indicative of the positions of (i) the multiple electrodes, and (ii) the first and second electrodes (52a, 52b), respectively; and calculating the positions of the multiple electrodes disposed on the balloon, based on the received position signals and on a known distance between the first and second electrodes (52a, 52b), wherein calculating the positions of the multiple electrodes comprises scaling the positions of the multiple electrodes based on the known distance between the first and second electrodes (52a, 52b) and the received position signals from the first and second electrodes (52a, 52b).
A microwave aerial for a filling level gauge, with a cavity having a radiating opening, wherein the radiating opening is capable of being closed by an HF-permeable disc, wherein - at least one sealing medium (8, 9) is provided for sealing off the transition between the disc and the microwave aerial, wherein - an abutment face on a surface forming the cavity of the aerial surrounds the cylindrical peripheral face of the disc in a substantially positively locking manner and - a step-shaped taper of the peripheral face of the disc is provided, characterized in that - the disc is designed in such a way that the cylindrical peripheral face thereof tapers in a conical manner in the direction of the cavity of the aerial, and - the disc is fixed in position in the cavity of the aerial by means of a retaining ring, and - the retaining ring is arranged on a step of the step-shaped taper of the peripheral face of the disc, wherein in order to widen or spread the retaining ring into the continuous groove formed on the abutment face during the insertion of the disc into the cavity of the aerial a transition is formed in a conically tapering manner on the peripheral face between the step receiving the retaining ring and the step adjoining in the direction of the taper of the peripheral face. - at least one sealing medium (8, 9) is provided for sealing off the transition between the disc and the microwave aerial, wherein - an abutment face on a surface forming the cavity of the aerial surrounds the cylindrical peripheral face of the disc in a substantially positively locking manner and - a step-shaped taper of the peripheral face of the disc is provided, characterized in that - the disc is designed in such a way that the cylindrical peripheral face thereof tapers in a conical manner in the direction of the cavity of the aerial, and - the disc is fixed in position in the cavity of the aerial by means of a retaining ring, and - the retaining ring is arranged on a step of the step-shaped taper of the peripheral face of the disc, wherein in order to widen or spread the retaining ring into the continuous groove formed on the abutment face during the insertion of the disc into the cavity of the aerial a transition is formed in a conically tapering manner on the peripheral face between the step receiving the retaining ring and the step adjoining in the direction of the taper of the peripheral face.
Clamp collar (40, 40') comprising a band (41, 41'), preferably made of metal, having at least one pair of ends (42 and 43) spaced apart in the circumferential direction, connecting means for connecting the or each pair of ends together with adjustable tightening in this direction and a locking member (45, 45') for locking the connecting means, characterized in that this member is mounted solid with one of these ends and is able to occupy an unlocked position in which it is disengaged from these means for tightening and loosening the collar and a locked position in which it engages with them to oppose this loosening.
Sensor arrangement, comprising: a barometric pressure sensor; and a thermal gas sensor; characterized in that the thermal gas sensor is arranged on the barometric pressure sensor such that a gas-permeable measurement structure of the thermal gas sensor is arranged in front of a gas inlet opening of the barometric pressure sensor or in front of a pressure-sensitive surface of the barometric pressure sensor; wherein the thermal gas sensor comprises a frame that is arranged on the barometric pressure sensor, and wherein the frame carries the gas-permeable measurement structure such that active areas of the gas-permeable measurement structure span a free inner area of the thermal gas sensor surrounded by the frame; wherein the gas inlet opening of the barometric pressure sensor or the pressure-sensitive surface of the barometric pressure sensor borders on the free inner area of the thermal gas sensor. a barometric pressure sensor; and a thermal gas sensor; characterized in that the thermal gas sensor is arranged on the barometric pressure sensor such that a gas-permeable measurement structure of the thermal gas sensor is arranged in front of a gas inlet opening of the barometric pressure sensor or in front of a pressure-sensitive surface of the barometric pressure sensor; wherein the thermal gas sensor comprises a frame that is arranged on the barometric pressure sensor, and wherein the frame carries the gas-permeable measurement structure such that active areas of the gas-permeable measurement structure span a free inner area of the thermal gas sensor surrounded by the frame; wherein the gas inlet opening of the barometric pressure sensor or the pressure-sensitive surface of the barometric pressure sensor borders on the free inner area of the thermal gas sensor.
A slide rail assembly, comprising: a first rail; a second rail (16, 200) movably connected to the first rail and including a reinforcement structure (28, 202), wherein the second rail (16, 200) includes a front portion and a rear portion, and the reinforcement structure (28, 202) is located between the front portion and the rear portion, and wherein the reinforcement structure (28, 202) includes a first portion and a second portion opposite the first portion and wherein the reinforcement structure (28, 202) is a plate longitudinally and fixedly connected to the second rail (16, 200); and a third rail movably connected to the second rail (16, 200); wherein when the slide rail assembly is in an extended state, each of the second rail (16, 200) and the third rail is at an extended position with respect to the first rail, the second rail (16, 200) is located between the first rail and the third rail, the first portion of the reinforcement structure (28, 202) is at a position corresponding to the third rail, and the second portion of the reinforcement structure (28, 202) is at a position corresponding to the first rail; and the slide rail assembly is adapted for mounting an object to a rack; and wherein the first rail is mounted to the rack, and the third rail is mounted with the object. a first rail; a second rail (16, 200) movably connected to the first rail and including a reinforcement structure (28, 202), wherein the second rail (16, 200) includes a front portion and a rear portion, and the reinforcement structure (28, 202) is located between the front portion and the rear portion, and wherein the reinforcement structure (28, 202) includes a first portion and a second portion opposite the first portion and wherein the reinforcement structure (28, 202) is a plate longitudinally and fixedly connected to the second rail (16, 200); and a third rail movably connected to the second rail (16, 200); wherein when the slide rail assembly is in an extended state, each of the second rail (16, 200) and the third rail is at an extended position with respect to the first rail, the second rail (16, 200) is located between the first rail and the third rail, the first portion of the reinforcement structure (28, 202) is at a position corresponding to the third rail, and the second portion of the reinforcement structure (28, 202) is at a position corresponding to the first rail; and the slide rail assembly is adapted for mounting an object to a rack; and wherein the first rail is mounted to the rack, and the third rail is mounted with the object.
A bobsleigh or luge track comprising at least one curved construction element of concrete, having a sprayed reinforced cast-in-situ concrete carrier layer, characterised in that the cast-in-situ concrete carrier layer is combined with a lost formwork having a doubly curved visible surface and comprising prefabricated shell portions produced from high-strength concrete.
A steering column comprising a leg, a fairing, an inner tube, an outer tube, a steering wheel stub and at least one adjustment geared motor unit (7, 8), the leg being axially mobile and the column comprising a geared motor unit operating the leg characterized in that the outer tube is axially mobile and in that an axial adjustment geared motor unit operates said outer tube.
A method for controlling a filling process of an operating fluid container, which can be filled via a filler pipe opening out into the operating fluid container by means of a filling device, wherein the operating fluid container has a venting valve, which can be electrically actuated between an open position, in which the operating fluid container is fluidically connected to the atmosphere, at least indirectly, by means of the venting valve, and a closed position, in which the operating fluid container is fluidically separated from the atmosphere by means of the venting valve, wherein the method has the following method steps: a) moving the venting valve into its open position; b) determining a filling level of the operating fluid container; characterized by the further procedural steps: c) reducing a venting volume flow through the venting valve if the filling level of the operating fluid container has reached or exceeded a predetermined shut-off filling level; d) determining a filling stop of the filling device; and e) moving the venting valve into its closed position after a predetermined time period after determining the filling stop. a) moving the venting valve into its open position; b) determining a filling level of the operating fluid container; characterized by the further procedural steps: c) reducing a venting volume flow through the venting valve if the filling level of the operating fluid container has reached or exceeded a predetermined shut-off filling level; d) determining a filling stop of the filling device; and e) moving the venting valve into its closed position after a predetermined time period after determining the filling stop.
A pocket mattress comprising coil springs arranged as spring units enclosed in a covering material forming pockets, the spring units being arranged successively in elongate strings, the mattress comprising a plurality of such interconnected strings arranged side by side, wherein the elongate strings have a plurality of transverse seams arranged parallel to the longitudinal direction of the coil springs to separate the pockets, wherein a middle portion of the transverse seams attaches at least a layer of covering material from either side of the spring unit to each other, characterized in that at least some of the transverse seams are back folded transverse seams, in which the covering material in proximity to an end portion of said back folded transverse seams is back folded towards the middle portion of the transverse seams, whereby said back folded transverse seams each have at least one end portion attaching at least twice as many layers of covering material as in a corresponding transverse seam which is not back folded.
Process to stop and/or prevent the spreading of peat fire consisting of: - digging a trench in the periphery of the area of outbreak of fire or potential fire, - filling a trench at least partially with at least one superabsorbent (co)polymer, said superabsorbent (co)polymer being: - either partially or totally swollen with water before filling the trench, - either directly deposited in the trench and then totally or partially swollen by previously or subsequently supplying water. - digging a trench in the periphery of the area of outbreak of fire or potential fire, - filling a trench at least partially with at least one superabsorbent (co)polymer, said superabsorbent (co)polymer being: - either partially or totally swollen with water before filling the trench, - either directly deposited in the trench and then totally or partially swollen by previously or subsequently supplying water.
An organic photoelectric conversion element comprising: a transparent first electrode; a power generation layer having a p-type organic semiconductor material and an n-type organic semiconductor material; and a second electrode, on a transparent substrate, wherein the power generation layer is a bulk heterojunction power generation layer including the p-type organic semiconductor material and the n-type organic semiconductor material, and additionally comprises a compound represented by general formula shown below: wherein R 1 represents a substituted or unsubstituted aryl group, Z 1 and Z 2 each represents a substituted or unsubstituted alkylene group having 1 to 3 carbon atoms, provided that sum of the carbon atoms in the alkylene group represented by Z 1 and Z 2 is 3 to 6; A represents an oxygen atom, N-Z 3, or S n5, and Z 3 represents an alkyl group or an aryl group; n5 represents an integer of from 0 to 2; a transparent first electrode; a power generation layer having a p-type organic semiconductor material and an n-type organic semiconductor material; and a second electrode, on a transparent substrate,