mhurhangee/ep-ind-claims huggingface dataset:
A compound of formula: in which: R and R 1 are independently selected from the group consisting of: H, linear C1-C6 alkyl chain, benzyl and acetyl; R 2 is selected from the group consisting of: C1-C20 linear alkyl chain, C3-C10 branched alkyl chain, aryl, heteroaryl and C1-C10 linear alkyl chain substituted by aryl or heteroaryl; R 3 is selected from the group consisting of: halogen, haloalkyl and CN; the two rings shown are optionally and independently of each other replaced with one or more substituents independently selected from the group consisting of: halogen, linear or branched C1-C6 alkyl chain, haloalkyl, haloalkoxyl, CN, NO 2, NH 2, carboxylic ester, COOH and SH; or a salt, stereoisomer, solvate or tautomer thereof. R and R 1 are independently selected from the group consisting of: H, linear C1-C6 alkyl chain, benzyl and acetyl; R 2 is selected from the group consisting of: C1-C20 linear alkyl chain, C3-C10 branched alkyl chain, aryl, heteroaryl and C1-C10 linear alkyl chain substituted by aryl or heteroaryl; R 3 is selected from the group consisting of: halogen, haloalkyl and CN; the two rings shown are optionally and independently of each other replaced with one or more substituents independently selected from the group consisting of: halogen, linear or branched C1-C6 alkyl chain, haloalkyl, haloalkoxyl, CN, NO 2, NH 2, carboxylic ester, COOH and SH; or a salt, stereoisomer, solvate or tautomer thereof.
A compound of Formula I according to Formula I(w), Formula I(w'), or Formula I(w"): wherein R 1a is benzothiophene optionally substituted with 1, 2, or 3 R 7 groups; R 2 and R 3 together with the nitrogen to which they are attached form a 4-5 membered monocyclic heterocycloalkyl ring; R 4 is phenyl substituted with a halo and a cycloalkyloxy group; each R 7, when present, is independently nitro, cyano, amino, halo, or hydroxy, where at least one R 7 is halo; and optionally a tautomer, a single stereoisomer or mixture of stereoisomers thereof and additionally optionally a pharmaceutically acceptable salt thereof.
A fluid connection device, in particular for a motor vehicle, comprising: - a female nozzle having an internal fluid flow passage, and configured to receive a male nozzle, - elastic snap-in means carried by said female nozzle and configured to cooperate with said male nozzle when the latter is engaged in said female nozzle, - means for detecting the elastic snap-in of said male nozzle into said female nozzle, and - an electrical plug for electrically connecting the device to an electrical power source, said detection means comprising a flexible and electrically conductive dome which is housed in said female nozzle and which is elastically deformable from a free position without stress in which it has a generally curved shape, to a position stressed by pressing said male nozzle onto a vertex of the dome which then has a generally flattened shape and provides an electrical connection between two terminals (52, 54) connected to said electrical plug. - a female nozzle having an internal fluid flow passage, and configured to receive a male nozzle, - elastic snap-in means carried by said female nozzle and configured to cooperate with said male nozzle when the latter is engaged in said female nozzle, - means for detecting the elastic snap-in of said male nozzle into said female nozzle, and - an electrical plug for electrically connecting the device to an electrical power source,
A method, implemented by computer means, for providing a set-of-data relative to a wearer of an ophthalmic equipment and/or to at least part of the ophthalmic equipment to a data server, the set-of-data being intended to be used to determine the ophthalmic equipment adapted to the wearer, the method comprising: - a set-of-data receiving step, during which the set-of-data relative to the wearer and/or to at least part of the ophthalmic equipment is received from a first user, the set-of-data comprising a private data segment and a public data segment, the private data segment being protected by a private key providing an access to the data of the private data segment; - a set-of-data storing step, during which the set-of-data is stored on the data server and associated with an identifier; and - an identifier sending step, during which the identifier associated with the stored set-of-data is sent to a second user, characterised in that the data of the private data segment are encrypted with a private encryption key, and wherein the private encryption key and the private key are different. - a set-of-data receiving step, during which the set-of-data relative to the wearer and/or to at least part of the ophthalmic equipment is received from a first user, the set-of-data comprising a private data segment and a public data segment, the private data segment being protected by a private key providing an access to the data of the private data segment; - a set-of-data storing step, during which the set-of-data is stored on the data server and associated with an identifier; and - an identifier sending step, during which the identifier associated with the stored set-of-data is sent to a second user, the data of the private data segment are encrypted with a private encryption key, and wherein the private encryption key and the private key are different.
A reactor for treating water, the reactor comprising a buoyant structure for supporting at least one removably attachable cell for suspension in a body of water in use, wherein the at least one cell is modular and comprises two or more units, at least one of the two or more units being detachably attachable to another unit in a vertical configuration in use, or to the buoyant structure to vary the length of the cell, the at least one of the two or more units being arranged to house biomedia.
Kit comprising a screwdriver bit comprising a body having a first end portion comprising a first engaging structure adapted to engage a fastener head, an opposite second end portion, and an intermediate portion connecting said first end portion and said second end portion, wherein said second end portion comprises a second engaging structure adapted to engage a tip of a tool and wherein said second engaging structure is formed by at least one projecting structure (21a; 21b; 21c) extending in an axial direction A-A, and a tightening tool comprising a set screw for locking said bit in said tightening tool, said set screw comprising a thread for engaging a corresponding thread in a through hole at a front end of said tightening tool to lock said bit and a rear surface comprising engaging means adapted to engage a tool tip of a first type, wherein the second engaging structure of said screwdriver bit adapted to engage a tip of a tool is adapted to engage a tool tip of said first type. a first end portion comprising a first engaging structure adapted to engage a fastener head, an opposite second end portion, and an intermediate portion connecting said first end portion and said second end portion, wherein said second end portion comprises a second engaging structure adapted to engage a tip of a tool and wherein said second engaging structure is formed by at least one projecting structure (21a; 21b; 21c) extending in an axial direction A-A, and a tightening tool comprising a set screw for locking said bit in said tightening tool, said set screw comprising a thread for engaging a corresponding thread in a through hole at a front end of said tightening tool to lock said bit and a rear surface comprising engaging means adapted to engage a tool tip of a first type, wherein the second engaging structure of said screwdriver bit adapted to engage a tip of a tool is adapted to engage a tool tip of said first type. a tightening tool comprising a set screw for locking said bit in said tightening tool, said set screw comprising a thread for engaging a corresponding thread in a through hole at a front end of said tightening tool to lock said bit and a rear surface comprising engaging means adapted to engage a tool tip of a first type, wherein the second engaging structure of said screwdriver bit adapted to engage a tip of a tool is adapted to engage a tool tip of said first type.
A folding frame for strollers, baby carriages or the like, comprising a lower framework provided with at least one front post and at least one rear post which are connected in a lower region to respective wheel assemblies (3a, 3b), said at least one rear post being movable on command, with respect to said at least one front post, with a rotary motion about a first articulation axis that is substantially transverse to the direction of longitudinal extension of said folding frame during the transition of said folding frame from an extended open condition to a collapsed closed condition and vice versa, said lower framework being connected kinematically to at least one handle tube which forms at least one upper grip element and can move with respect to said at least one front post along a movement trajectory having at least one component that is parallel to the direction of main extension of said at least one front post, in order to move between an active condition, in which said grip element is spaced and arranged upward with respect to the end portion of said lower framework that is uppermost during use, and an inactive condition, in which said grip element is arranged so as to be close to said end portion of said lower framework that is uppermost during use, said lower framework supporting an actuation device which is provided with an actuation grip element, which can move on command between a first position and a second position, said actuation device being connected kinematically to at least one interconnection device for interconnection between said at least one rear post and at least one respective front post in order to pass, as a consequence of the transition of said actuation grip element between said first position and said second position, between an extended position, in which the respective front and rear posts (2a, 2b) are kept angularly spaced, and a folded position, in which the respective front and rear posts (2a, 2b) are kept angularly close, there being at least one first locking body, kinematically connected to said actuation grip element, for locking said interconnection device in the extended position and at least one second locking body which acts between said at least one front post and the respective handle tube, in order to keep said handle tube locked in said active position, characterized in that said interconnection device comprises a toggle device which comprises a first connecting body and a second connecting body, said first connecting body having a first end which is pivoted, about a third articulation axis which is substantially parallel to said first articulation axis, to a respective rear post, and a second end which is pivoted to said second connecting body about a fourth articulation axis which is substantially parallel to said third articulation axis, said second connecting body being supported so that it can rotate, about a fifth articulation axis which is substantially parallel to said third and fourth articulation axes (103, 104), by the respective front post.
Device for automatically hanging sausages, each having a hanger loop, on a carrying bar, a gripping means for the hanger loop, a transport device for the sausages hanging by their hanger loop and a means for discharging the transported sausages onto the carrying bar supported in the device as well as a controlling device being provided in the device, characterized in that optionally gripping a single sausage provided with a hanger loop is avoided is such a way that the hanger loop is not taken over by the gripping means, such that this sausage gets into a discharge of the device and not into the transport device.
A spinal treatment system comprising: a prosthesis adapted to be coupled with a spinal segment in a spine, wherein the prosthesis comprises a plurality of pedicle screws and a spinal stabilization rod coupled thereto, the plurality of pedicle screws configured to be threadably engaged with a pair of vertebrae to be fused in a spinal segment of the spine; and a constraint device comprising an essentially non-compliant upper tether portion, an essentially non-compliant lower tether portion and an elastically distensible compliance member coupled therebetween, the constraint device being configured to be disposed around a superior surface of a superior spinous process superior to the fused region and also around an inferior surface of an inferior spinous process that is part of superior region of the fused region, with the upper tether portion coupled with the superior spinous process and the lower tether portion coupled with the inferior spinous process or sacrum of the spinal segment, to restrict flexion of the spinal segment supradjacent to the fused region, and wherein length or tension in the constraint device is adjustable to provide a force resistant to flexion of the spine superior to the pair of vertebrae to be fused. wherein the prosthesis comprises a plurality of pedicle screws and a spinal stabilization rod coupled thereto, the plurality of pedicle screws configured to be threadably engaged with a pair of vertebrae to be fused in a spinal segment of the spine; and a constraint device comprising an essentially non-compliant upper tether portion, an essentially non-compliant lower tether portion and an elastically distensible compliance member coupled therebetween, the constraint device being configured to be disposed around a superior surface of a superior spinous process superior to the fused region and also around an inferior surface of an inferior spinous process that is part of superior region of the fused region, with the upper tether portion coupled with the superior spinous process and the lower tether portion coupled with the inferior spinous process or sacrum of the spinal segment, to restrict flexion of the spinal segment supradjacent to the fused region, and wherein length or tension in the constraint device is adjustable to provide a force resistant to flexion of the spine superior to the pair of vertebrae to be fused.
A method for controlling the complete opening of an exhaust valve of the combustion gas of a cylinder of an internal combustion engine, this cylinder comprising one or several exhaust valves, the opening of each valve being controlled by means of an electromechanical actuator comprising a control rod carrying a transverse plate moving in an air gap delimited by two electromagnets (12, 13) alternately attracting the plate in combination with a force created by torque springs (4, 7) acting on the rod, the plate moving in an oscillating manner from an intermediate balanced position, during which it is subjected solely to the forces of the torque springs, and two final positions in which the valve is in closed or open position, and in which the plate comes in contact with an electromagnet, characterized in that before proceeding to said complete opening of said valve by attracting the plate in a final position corresponding to the opening of the valve, an exhaust valve of this cylinder is opened under the action of solely the forces of the springs, in a phase designated as pilot opening, during which a decompression phase of the gas in the cylinder is thus carried out.
A process for adding amino acid residues to peptides, comprising: heating a stream comprising amino acids such that the temperature of the amino acids is increased by at least about 1 °C; and exposing the heated amino acids to a plurality of peptides immobilized on a solid support, wherein the heating step is performed prior to and within about 30 seconds of exposing the heated amino acids to the peptides. heating a stream comprising amino acids such that the temperature of the amino acids is increased by at least about 1 °C; and exposing the heated amino acids to a plurality of peptides immobilized on a solid support, wherein the heating step is performed prior to and within about 30 seconds of exposing the heated amino acids to the peptides.
A method of handling a response, said method comprising: receiving at a mobile communication device a response data unit from a peripheral device, said response data unit responsive to a command data unit previously transmitted to said peripheral device; determining (604, 606) at said mobile communication device that said response data unit is of a type distinct from a type of response data unit transmitted to an associated driver module as an anticipatory response data unit to said command data unit, said associated driver module executed on said mobile communication device; and storing, in a record at said mobile communication device, an indication that an incorrect anticipatory response data unit has been transmitted to said associated driver module. receiving at a mobile communication device a response data unit from a peripheral device, said response data unit responsive to a command data unit previously transmitted to said peripheral device; determining (604, 606) at said mobile communication device that said response data unit is of a type distinct from a type of response data unit transmitted to an associated driver module as an anticipatory response data unit to said command data unit, said associated driver module executed on said mobile communication device; and storing, in a record at said mobile communication device, an indication that an incorrect anticipatory response data unit has been transmitted to said associated driver module.
A device for enhancing angiograms, comprising: - a data input; - a data processor; and - an output interface; wherein the data input is configured to provide at least one angiographic image showing a vascular structure of interest comprising a plurality of vessel branches; wherein the data processor is configured to determine at least one branch of interest from the angiographic image; and to segment the angiographic image for identifying possible branches of the vascular structure; and to select branches based on the identified possible branches and the determined branch of interest; and to estimate attenuation values of the selected branches; and to subtract at least a predetermined part of the estimated attenuation values from the angiographic image to generate a corrected angiogram; and wherein the output interface is configured to provide the corrected angiogram. - a data input; - a data processor; and - an output interface; wherein the data input is configured to provide at least one angiographic image showing a vascular structure of interest comprising a plurality of vessel branches; wherein the data processor is configured to determine at least one branch of interest from the angiographic image; and to segment the angiographic image for identifying possible branches of the vascular structure; and to select branches based on the identified possible branches and the determined branch of interest; and to estimate attenuation values of the selected branches; and to subtract at least a predetermined part of the estimated attenuation values from the angiographic image to generate a corrected angiogram; and wherein the output interface is configured to provide the corrected angiogram.
Rubber composition based on at least an elastomer, a reinforcing filler and a crosslinking system and a crumb rubber, said crumb having an isoprene elastomer content of greater than 50 phr in the composition of the crumb and a chloroform extract with a weight-average molecular weight of less than 10 000 g/mol.
An electric oral hygiene device storage container comprising: a removable electric oral hygiene device; a first casing part; at least a second casing part; which first and second casing parts are mechanically coupled to allow for an open container state in which the electric oral hygiene device can be removed from the container and a closed container state in which the electric oral hygiene device is secured inside of the container; wherein the container further has a charging unit for selectively charging the electric oral hygiene device, an electrical input connector realized at an outer side of the first or second casing part (10, 20) for providing energy to the charging unit, and at least one electrical output connector, wherein the charging unit is arranged for selectively providing the energy received at the electrical input connector via the electrical output connector to an external device, characterised in that the at least one electrical output connector is realized at an outer side of the first or second casing part (10, 20). a removable electric oral hygiene device; a first casing part; at least a second casing part; which first and second casing parts are mechanically coupled to allow for an open container state in which the electric oral hygiene device can be removed from the container and a closed container state in which the electric oral hygiene device is secured inside of the container; wherein the container further has a charging unit for selectively charging the electric oral hygiene device, an electrical input connector realized at an outer side of the first or second casing part (10, 20) for providing energy to the charging unit, and at least one electrical output connector, wherein the charging unit is arranged for selectively providing the energy received at the electrical input connector via the electrical output connector to an external device, characterised in that the at least one electrical output connector is realized at an outer side of the first or second casing part (10, 20).
Nozzle comprising - a nozzle insert; - a nozzle carrier having a cavity which is used as a receptacle for the nozzle insert and has a depth T, and having a groove which extends circumferentially around the cavity, has a depth t and forms a clamping web which extends circumferentially around the cavity; - a clamping element having a formation which can be fit into the groove, characterized in that the nozzle carrier and the clamping element each form a nozzle body half and, when fit together, form a nozzle body. - a nozzle insert; - a nozzle carrier having a cavity which is used as a receptacle for the nozzle insert and has a depth T, and having a groove which extends circumferentially around the cavity, has a depth t and forms a clamping web which extends circumferentially around the cavity; - a clamping element having a formation which can be fit into the groove, characterized in that the nozzle carrier and the clamping element each form a nozzle body half and, when fit together, form a nozzle body.
Functional unit for a storage tank for a liquid reducing agent, it being possible for the functional unit to be provided in the bottom of the storage tank, having a pumping device which is set up to deliver the reducing agent from the storage tank, characterized in that there is a gap which acts as a throttle between an opening, which is configured in a vertical section of a suction line, and a lower end of a substantially vertically arranged pipe, the suction line being connected hydraulically via the gap to a first reservoir for reducing agent, and the pipe ending just below a filter element and being set up for the intake of air which can collect below the filter element.