A human supervised system comprising: an adaptive user interface; a computerized computational element; at least one psycho physiological sensor, wherein a psycho physiological sensor is a sensor that is operable to sense at least one characteristic of an operator, wherein the operator is a human operator of the human supervised system, and communicate the at least one characteristic to the computerized computational element; a plurality of cyber-physical systems, wherein a cyber-physical system is a system that comprises a plurality of computational elements that collaborate to control one or more physical entities, each of said cyber-physical systems in communication with the computerized computational element, wherein each of said plurality of cyber physical systems includes at least one cyber-physical system sensor operable to sense a characteristic of the corresponding cyber-physical system; the computerized computational element comprising at least one processor and a memory, wherein the memory stores a cyber-physical systems state estimator module operable to estimate a state of a cyber-physical system based on an output of the at least one cyber-physical system sensor, a human state estimator module operable to estimate a state of at least one operator based on said at least one characteristic of the operator, a data fusion module operable to merge the state of the operator and the state of each of said cyber-physical systems into a single human supervised cyber-physical system state, a high level cyber-physical systems controller operable to generate high level control commands for each of said cyber-physical systems in response to said single human supervised cyber-physical system state; and a recommender optimizer module operable to cause said adaptive user interface to adapt in response to said single human supervised cyber-physical system state by at least displaying recommended optimization of the user interface to the human operator. an adaptive user interface; a computerized computational element; at least one psycho physiological sensor, wherein a psycho physiological sensor is a sensor that is operable to sense at least one characteristic of an operator, wherein the operator is a human operator of the human supervised system, and communicate the at least one characteristic to the computerized computational element; a plurality of cyber-physical systems, wherein a cyber-physical system is a system that comprises a plurality of computational elements that collaborate to control one or more physical entities, each of said cyber-physical systems in communication with the computerized computational element, wherein each of said plurality of cyber physical systems includes at least one cyber-physical system sensor operable to sense a characteristic of the corresponding cyber-physical system; the computerized computational element comprising at least one processor and a memory, wherein the memory stores a cyber-physical systems state estimator module operable to estimate a state of a cyber-physical system based on an output of the at least one cyber-physical system sensor, a human state estimator module operable to estimate a state of at least one operator based on said at least one characteristic of the operator, a data fusion module operable to merge the state of the operator and the state of each of said cyber-physical systems into a single human supervised cyber-physical system state, a high level cyber-physical systems controller operable to generate high level control commands for each of said cyber-physical systems in response to said single human supervised cyber-physical system state; and a recommender optimizer module operable to cause said adaptive user interface to adapt in response to said single human supervised cyber-physical system state by at least displaying recommended optimization of the user interface to the human operator. a cyber-physical systems state estimator module operable to estimate a state of a cyber-physical system based on an output of the at least one cyber-physical system sensor, a human state estimator module operable to estimate a state of at least one operator based on said at least one characteristic of the operator, a data fusion module operable to merge the state of the operator and the state of each of said cyber-physical systems into a single human supervised cyber-physical system state, a high level cyber-physical systems controller operable to generate high level control commands for each of said cyber-physical systems in response to said single human supervised cyber-physical system state; and a recommender optimizer module operable to cause said adaptive user interface to adapt in response to said single human supervised cyber-physical system state by at least displaying recommended optimization of the user interface to the human operator.