A suturing apparatus comprising: an anchored suture line formed of a bio-compatible suture thread upon which is located a plurality of anchor structures; and a suturing device, preloaded with said anchored suture line, said suturing device comprising: a device body with a substantially cylindrical shape with distal and proximal faces, said device body defining a hollow cylindrical cavity about an axis of said device body, said hollow cylindrical cavity having a cavity diameter and penetrating said distal face; an injector tip, mounted on said distal face coaxially with said axis, said injector tip comprising a hollow needle injector having a bore diameter substantially equal to the diameter of said cavity through which said anchor structures may pass; a cylindrical anchor drive piston, coaxially located within said hollow cylindrical cavity, the diameter of said cylindrical anchor drive piston selected to allow axial displacement through said hollow cylindrical cavity and said bore of hollow needle, said cylindrical anchor drive piston being hollow and defining a coaxial piston cavity; and an anchor feed mechanism (240, 210) contained within said device body configured to feed one of said anchor structures into said hollow needle injector, at each of a succession of laterally displaced tissue puncture locations, wherein said plurality of anchor structures are permanently attached to said suture thread at predetermined intervals; characterised in that: said anchor feed mechanism (240, 210) comprises said coaxial piston cavity and a distal face of said coaxial piston, said anchored suture line being preloaded within said coaxial piston cavity; and said anchor structures are comprised of self-expandable compressed matrix collagen-based polymer that volumetrically expands on contact with bodily fluids, distinct from said first bio-compatible suture thread material, and that can be caused to transition from a compressed state to an expanded state after implantation in biological tissue. an anchored suture line formed of a bio-compatible suture thread upon which is located a plurality of anchor structures; and a suturing device, preloaded with said anchored suture line, said suturing device comprising: a device body with a substantially cylindrical shape with distal and proximal faces, said device body defining a hollow cylindrical cavity about an axis of said device body, said hollow cylindrical cavity having a cavity diameter and penetrating said distal face; an injector tip, mounted on said distal face coaxially with said axis, said injector tip comprising a hollow needle injector having a bore diameter substantially equal to the diameter of said cavity through which said anchor structures may pass; a cylindrical anchor drive piston, coaxially located within said hollow cylindrical cavity, the diameter of said cylindrical anchor drive piston selected to allow axial displacement through said hollow cylindrical cavity and said bore of hollow needle, said cylindrical anchor drive piston being hollow and defining a coaxial piston cavity; and an anchor feed mechanism (240, 210) contained within said device body configured to feed one of said anchor structures into said hollow needle injector, at each of a succession of laterally displaced tissue puncture locations, wherein a device body with a substantially cylindrical shape with distal and proximal faces, said device body defining a hollow cylindrical cavity about an axis of said device body, said hollow cylindrical cavity having a cavity diameter and penetrating said distal face; an injector tip, mounted on said distal face coaxially with said axis, said injector tip comprising a hollow needle injector having a bore diameter substantially equal to the diameter of said cavity through which said anchor structures may pass; a cylindrical anchor drive piston, coaxially located within said hollow cylindrical cavity, the diameter of said cylindrical anchor drive piston selected to allow axial displacement through said hollow cylindrical cavity and said bore of hollow needle, said cylindrical anchor drive piston being hollow and defining a coaxial piston cavity; and an anchor feed mechanism (240, 210) contained within said device body configured to feed one of said anchor structures into said hollow needle injector, at each of a succession of laterally displaced tissue puncture locations, wherein said plurality of anchor structures are permanently attached to said suture thread at predetermined intervals; characterised in that: said anchor feed mechanism (240, 210) comprises said coaxial piston cavity and a distal face of said coaxial piston, said anchored suture line being preloaded within said coaxial piston cavity; and said anchor structures are comprised of self-expandable compressed matrix collagen-based polymer that volumetrically expands on contact with bodily fluids, distinct from said first bio-compatible suture thread material, and that can be caused to transition from a compressed state to an expanded state after implantation in biological tissue. said anchor feed mechanism (240, 210) comprises said coaxial piston cavity and a distal face of said coaxial piston, said anchored suture line being preloaded within said coaxial piston cavity; and said anchor structures are comprised of self-expandable compressed matrix collagen-based polymer that volumetrically expands on contact with bodily fluids, distinct from said first bio-compatible suture thread material, and that can be caused to transition from a compressed state to an expanded state after implantation in biological tissue.