mhurhangee/ep-ind-claims huggingface dataset:
A method of detecting a condition in a first amplification reaction comprising: assembling a first mixture, wherein the first mixture comprises a first nucleic acid template, a second nucleic acid template, a first set of primers specific for the first nucleic acid template, and a sample comprising sample nucleic acids; carrying out the first amplification reaction with the first mixture for a first number of cycles to generate a product; assembling a second mixture, wherein the second mixture comprises the product, a second set of primers specific for the second nucleic acid template, and a third set of primers specific for an amplification product of the first nucleic acid template; carrying out a second amplification reaction with the second mixture, wherein the second amplification reaction is quantitative; determining and comparing the number of cycles required to reach Cq for amplification of the first nucleic acid template and the number of cycles required to reach Cq for amplification of the second template; and wherein a condition in the first amplification reaction is detected when the difference between the number of cycles required to reach Cq2 and the number of cycles required to reach Cq1 is less than a threshold number of cycles. assembling a first mixture, wherein the first mixture comprises a first nucleic acid template, a second nucleic acid template, a first set of primers specific for the first nucleic acid template, and a sample comprising sample nucleic acids; carrying out the first amplification reaction with the first mixture for a first number of cycles to generate a product; assembling a second mixture, wherein the second mixture comprises the product, a second set of primers specific for the second nucleic acid template, and a third set of primers specific for an amplification product of the first nucleic acid template; carrying out a second amplification reaction with the second mixture, wherein the second amplification reaction is quantitative; determining and comparing the number of cycles required to reach Cq for amplification of the first nucleic acid template and the number of cycles required to reach Cq for amplification of the second template; and wherein a condition in the first amplification reaction is detected when the difference between the number of cycles required to reach Cq2 and the number of cycles required to reach Cq1 is less than a threshold number of cycles.
An apparatus for cardiac hemodynamic optimization and monitoring, comprising: a self-expanding body (220, 250) having a proximal end and a distal end; a prosthetic heart valve disposed in the body; a tether extending from the proximal end of the body; and an electrode coupled to the tether, the electrode being in electrical communication with a pulse generator configured to deliver electrical signals to the electrode; and an apical pad configured to couple to a proximal end portion of the tether wherein the electrode is coupled to an upper surface of the apical pad. a self-expanding body (220, 250) having a proximal end and a distal end; a prosthetic heart valve disposed in the body; a tether extending from the proximal end of the body; and an electrode coupled to the tether, the electrode being in electrical communication with a pulse generator configured to deliver electrical signals to the electrode; and an apical pad configured to couple to a proximal end portion of the tether wherein the electrode is coupled to an upper surface of the apical pad.
Method for determining the concentration of a carbapenem antibiotic in a biological sample, comprising the steps of (a) providing beta-lactamase class D OXA-48 (OXA-48) having an amino acid sequence as set forth in SEQ ID NO: 1 or SEQ ID NO: 29, or a functionally active variant or fragment thereof having carbapenem-hydrolysing class D beta-lactamase activity, wherein the functionally active variant has at least about 90% sequence identity to the amino acid sequence as set forth in SEQ ID NO: 1 or SEQ ID NO: 29; (b) contacting the OXA-48 or functionally active variant or fragment thereof with the biological sample; and (c) determining the concentration of the carbapenem antibiotic in the biological sample. (a) providing beta-lactamase class D OXA-48 (OXA-48) having an amino acid sequence as set forth in SEQ ID NO: 1 or SEQ ID NO: 29, or a functionally active variant or fragment thereof having carbapenem-hydrolysing class D beta-lactamase activity, wherein the functionally active variant has at least about 90% sequence identity to the amino acid sequence as set forth in SEQ ID NO: 1 or SEQ ID NO: 29; (b) contacting the OXA-48 or functionally active variant or fragment thereof with the biological sample; and (c) determining the concentration of the carbapenem antibiotic in the biological sample.
A system for monitoring a plurality of circuit branches coupled to an input line, the system comprising a communication bus; a plurality of sensor circuits, each configured to be coupled to the communication bus and at least one of the plurality of circuit branches, wherein each sensor circuit is further configured to sample current in the at least one of the plurality of circuit branches; and a controller configured to be coupled to the communication bus and the input line; wherein the controller is further configured to: sample voltage on the input line; detect a voltage waveform on the input line; determine a phase angle of the voltage waveform at which current and voltage sampling should occur; broadcast, at a time based on the determined phase angle, a signal to each one of the plurality of sensor circuits to begin sampling current in a respective one of the plurality of circuit branches; sample, at the time based on the determined phase angle, voltage on the input line; receive, via the communication bus, current sampling data from at least one of the plurality of sensor circuits; and calculate at least one of RMS current, power, or energy usage of at least one of the plurality of circuit branches based on the current sampling data received from the at least one of the plurality of sensor circuits and voltage sampling data. sample voltage on the input line; detect a voltage waveform on the input line; determine a phase angle of the voltage waveform at which current and voltage sampling should occur; broadcast, at a time based on the determined phase angle, a signal to each one of the plurality of sensor circuits to begin sampling current in a respective one of the plurality of circuit branches; sample, at the time based on the determined phase angle, voltage on the input line; receive, via the communication bus, current sampling data from at least one of the plurality of sensor circuits; and calculate at least one of RMS current, power, or energy usage of at least one of the plurality of circuit branches based on the current sampling data received from the at least one of the plurality of sensor circuits and voltage sampling data.
A forging assembly, comprising: a first die defining a cavity; a second die configured to translate toward the first die and including a protrusion configured to be received by the cavity; a first sensor coupled to the first die and located in the cavity, wherein the first sensor is configured to output a first signal correlating to a first distance between the first die and the second die; and a second sensor coupled to the first die and located in the cavity, characterised in that the second sensor is configured to output a second signal correlating to a second distance between the first die and the second die, wherein the first distance is measured in a first direction and wherein the second distance is measured in a second direction orthogonal to the first direction, and wherein the first sensor and the second sensor are each a capacitance sensor. a first die defining a cavity; a second die configured to translate toward the first die and including a protrusion configured to be received by the cavity; a first sensor coupled to the first die and located in the cavity, wherein the first sensor is configured to output a first signal correlating to a first distance between the first die and the second die; and a second sensor coupled to the first die and located in the cavity, characterised in that the second sensor is configured to output a second signal correlating to a second distance between the first die and the second die, wherein the first distance is measured in a first direction and wherein the second distance is measured in a second direction orthogonal to the first direction, and wherein the first sensor and the second sensor are each a capacitance sensor.
A refrigerator and/or freezer with at least one body that encloses at least one cooled interior space, and with at least one first and one second door opening in opposite directions, which doors are articulated to the body, by means of which the interior space can be closed, wherein one or both doors include at least one seal (20, 20') that in the closed condition of the doors is disposed in the gap between the doors, wherein the at least one seal is in its closed end position when the doors are closed, wherein the appliance includes at least one door opening sensor and at least one drive unit (A, A') communicating with the same, which is configured to move the at least one seal of a door away from the other door from the closed end position into the open end position of the seal, wherein the open end position of the seal is a position of the seal where the seal has a smaller distance to its counter surface than in the closed end position, wherein the drive unit furthermore is configured such that the same is activated when the door opening sensor detects the opening of a door or the touching of the appliance by a user, characterized in that the drive unit is configured as a pneumatic or hydraulic drive unit.
A heating system for heating a living being, the heating system (22; 222) comprising an infrared laser system (5, 6; 205) for illuminating the living being (2; 202) with infrared laser light, thereby heating the living being (2; 202), characterized in that heating of the living being (2; 202) by means of illuminating the living being (2; 202) with the infrared laser light can be confined to a location of the living being (2; 202) based on the collimation of the infrared laser light.
A hearing device (HA1, HA2, HD), e.g. a hearing aid, comprising a first part for being inserted in an ear canal or fully or partially implanted in the head of a user, the first part comprising at least one electrode unit, termed a physiological response electrode (PR-electrode) unit, for making contact to skin or tissue of a user when mounted or implanted in an operational condition, the at least one PR-electrode unit being configured to pick up a physiological response from the user, wherein the at least one PR-electrode unit comprises an electrode (PR-EL; Electrode) comprising an electrically conductive material, and wherein the hearing device further comprises a housing or a guiding element, CHARACTERIZED IN THAT said electrode, termed a PR-electrode, is adapted to have an outer surface that is flush with or depressed in the surface of the housing (ITE (mould)) or guiding element (Micro-mould) of the first part at temperatures below a threshold temperature (T th), and to protrude from the surface when heated to temperatures at or above said threshold temperature (T th).
A composition for use in treatment of ischemic cerebrovascular disease, ischemic heart disease, myocardial infarction, Alzheimer's disease, Parkinson's disease, Lewy body disease, multiple sclerosis, amyotrophic lateral sclerosis, or spinal cord injury, the composition comprising the secretome of poly-sialylated neural cell adhesion molecule (PSA-NCAM)-positive neural precursor cells (NPCs) as an active ingredient, wherein the PSA-NCAM-positive neural precursor cells are separated from neural rosettes differentiated from pluripotent stem cells, and the pluripotent stem cells are embryonic stem cells, or induced pluripotent stem cells (iPSCs), wherein the secretome is in a form of being contained in a cell culture liquid obtained by culturing the PSA-NCAM-positive neural precursor cells in cell culture medium, wherein the secretome is obtained by removing the cells from the cell culture medium.
A roof panel comprising: - a lower metal sheet which is flat, - an upper metal sheet, which is corrugated, wherein the corrugations of the upper metal sheet are formed by a plurality of gutters, - one or more channels being provided on the lower metal sheet and extending uninterruptedly along the direction of the long edge of the roof panel, the one or more channels comprising a channel upper metal sheet connected to the top of the lower metal sheet such as to form a channel inner cavity, the one or more channels being suitable for multi-purpose use, - a thermal insulation material being located on and tightly adhered to the upper surface of the channel upper metal sheet of the one or more channels and fully extending between the lower and upper metal sheets (1, 4) of the panel, except for the channel inner cavity of the one or more channels, wherein the channel upper metal sheet of at least one of the one or more channels is located under one of the plurality of gutters and is placed at a distance from the upper metal sheet of the panel with the thermal insulation material extending in between, wherein the tight connection between the upper metal sheet, the thermal insulation material, the channel upper metal sheet and the lower metal sheet allows for a stronger composite material with a higher load carrying capacity than the total of the load capacities of each component taken separately, and the roof panel further comprising: - holes which are made on the surface of the lower metal sheet of the panel such as to face a channel inner cavity, said holes being made in a suitable number, size and shape for inlet-outlet apparatuses or acoustic, decorative requirements depending on the purpose of use of the one or more channels. - a lower metal sheet which is flat, - an upper metal sheet, which is corrugated, wherein the corrugations of the upper metal sheet are formed by a plurality of gutters, - one or more channels being provided on the lower metal sheet and extending uninterruptedly along the direction of the long edge of the roof panel, the one or more channels comprising a channel upper metal sheet connected to the top of the lower metal sheet such as to form a channel inner cavity, the one or more channels being suitable for multi-purpose use, - a thermal insulation material being located on and tightly adhered to the upper surface of the channel upper metal sheet of the one or more channels and fully extending between the lower and upper metal sheets (1, 4) of the panel, except for the channel inner cavity of the one or more channels, - holes which are made on the surface of the lower metal sheet of the panel such as to face a channel inner cavity, said holes being made in a suitable number, size and shape for inlet-outlet apparatuses or acoustic, decorative requirements depending on the purpose of use of the one or more channels.
An after-fan system for a gas turbine engine, comprising: a variable pitch fan exit guide vane array; and a control operable to vary a pitch of the variable fan exit guide vane array; characterized in comprising a short span after-fan turbine downstream of the variable pitch fan exit guide vane array and upstream of a bypass or secondary airflow path (B, 140) and a core airflow path (C, 142), the short span after-fan turbine being positioned between an outer profile of a core static structure and a ring splitter located radially inboard of an inner periphery of a fan nacelle or outer case structure (72, 136), the short span after-fan turbine being contained radially within the ring splitter. a variable pitch fan exit guide vane array; and a control operable to vary a pitch of the variable fan exit guide vane array; characterized in comprising a short span after-fan turbine downstream of the variable pitch fan exit guide vane array and upstream of a bypass or secondary airflow path (B, 140) and a core airflow path (C, 142), the short span after-fan turbine being positioned between an outer profile of a core static structure and a ring splitter located radially inboard of an inner periphery of a fan nacelle or outer case structure (72, 136), the short span after-fan turbine being contained radially within the ring splitter.
Plain bearing material having from 50 to 85% by volume of a fluoropolymer as a base material and having filling materials which comprise zinc sulphide and barium sulphate and optionally up to 40% by volume, with respect to the total filling material content, of additional filling materials, wherein the volume ratio of zinc sulphide to barium sulphate is between 0.1 and 15.7, preferably between 0.8 and 4.88 and in a particularly preferred manner between 1.5 and 3.44.
A display device having an active region and a non-active region, the display device comprising: a first substrate comprising a plurality of light-emitting units in the active region; a second substrate comprising a plurality of light conversion units in the active region; a sealing layer disposed between the first substrate and the second substrate, wherein the sealing layer comprises: a first portion disposed in the non-active region and a second portion disposed in the active region; the display device is characterized in that the sealing layer comprises: a plurality of first supporting elements disposed in the first portion and a plurality of second supporting element disposed in the second portion, wherein a density of the plurality of first supporting elements in the first portion is greater than a density of the plurality of second supporting elements in the second portion; a supporting force of the plurality of second supporting elements is greater than a supporting force of the plurality of first supporting elements; wherein the first substrate further comprises a plurality of dams disposed in the non-active region, and the first portion of the sealing layer is disposed between the dams. a first substrate comprising a plurality of light-emitting units in the active region; a second substrate comprising a plurality of light conversion units in the active region; a sealing layer disposed between the first substrate and the second substrate, wherein the sealing layer comprises: a first portion disposed in the non-active region and a second portion disposed in the active region; the display device is characterized in that the sealing layer comprises: a plurality of first supporting elements disposed in the first portion and a plurality of second supporting element disposed in the second portion, wherein a density of the plurality of first supporting elements in the first portion is greater than a density of the plurality of second supporting elements in the second portion; a supporting force of the plurality of second supporting elements is greater than a supporting force of the plurality of first supporting elements; a plurality of first supporting elements disposed in the first portion and a plurality of second supporting element disposed in the second portion, wherein a density of the plurality of first supporting elements in the first portion is greater than a density of the plurality of second supporting elements in the second portion; a supporting force of the plurality of second supporting elements is greater than a supporting force of the plurality of first supporting elements; wherein the first substrate further comprises a plurality of dams disposed in the non-active region, and the first portion of the sealing layer is disposed between the dams.
A catheter assembly (10, 110, 210, 310, 510, 610, 710, 810, 910, 1010) comprising: a catheter (30, 130, 230, 330, 430A to 430H, 530, 630, 730, 830, 930, 1030) having a first lumen (34, 134, 234, 334, α, 534, 634, 734, 834, 934, 1034) and a second lumen (41, 141, 241, 341, β, β1, P2, 540, 545, 641, 741, 841, 941); and an inner needle inserted through the first lumen (34, 134, 234, 334, α, 534, 634, 734, 834, 934, 1034), wherein the inner needle is provided with an introduction path (12a, 14, 113) for flashback confirmation allowing blood to flow between the catheter (30, 130, 230, 330, 430A to 430H, 530, 630, 730, 830, 930, 1030) and the inner needle, and a gap between an outer peripheral surface of the inner needle and a distal end inner peripheral surface (36, 136, 236, 336) of the first lumen (34, 134, 234, 334, α, 534, 634, 734, 834, 934, 1034) continuous with a distal end of the catheter (30, 130, 230, 330, 430A to 430H, 530, 630, 730, 830, 930, 1030) is narrower than a gap between the outer peripheral surface of the inner needle and a basic inner peripheral surface (38, 138, 238, 338) constituting most of an inner peripheral surface of the first lumen (34, 134, 234, 334, α, 534, 634, 734, 834, 934, 1034) on a proximal end side of the distal end inner peripheral surface (36, 136, 236, 336). a catheter (30, 130, 230, 330, 430A to 430H, 530, 630, 730, 830, 930, 1030) having a first lumen (34, 134, 234, 334, α, 534, 634, 734, 834, 934, 1034) and a second lumen (41, 141, 241, 341, β, β1, P2, 540, 545, 641, 741, 841, 941); and an inner needle inserted through the first lumen (34, 134, 234, 334, α, 534, 634, 734, 834, 934, 1034), wherein the inner needle is provided with an introduction path (12a, 14, 113) for flashback confirmation allowing blood to flow between the catheter (30, 130, 230, 330, 430A to 430H, 530, 630, 730, 830, 930, 1030) and the inner needle, and a gap between an outer peripheral surface of the inner needle and a distal end inner peripheral surface (36, 136, 236, 336) of the first lumen (34, 134, 234, 334, α, 534, 634, 734, 834, 934, 1034) continuous with a distal end of the catheter (30, 130, 230, 330, 430A to 430H, 530, 630, 730, 830, 930, 1030) is narrower than a gap between the outer peripheral surface of the inner needle and a basic inner peripheral surface (38, 138, 238, 338) constituting most of an inner peripheral surface of the first lumen (34, 134, 234, 334, α, 534, 634, 734, 834, 934, 1034) on a proximal end side of the distal end inner peripheral surface (36, 136, 236, 336).
A body comprising: a niobium carbide based cermet part containing a nickel based metallic binder; a silver based braze alloy; and at least one other part selected from a cermet, a cemented carbide or a part comprising a steel to which the cermet part is to be brazed to; characterized in that the cermet part contains at least 0.5 atomic percent molybdenum. a niobium carbide based cermet part containing a nickel based metallic binder; a silver based braze alloy; and at least one other part selected from a cermet, a cemented carbide or a part comprising a steel to which the cermet part is to be brazed to; characterized in that the cermet part contains at least 0.5 atomic percent molybdenum.
Apparatus for processing food masses, in particular fatty food masses, in particular for conching masses containing chocolate and/or cocoa, comprising - a container, - at least one, in particular horizontally arranged, shaft, which is equipped with tools, which are in particular arranged rotatably about the shaft axis, characterized in that the apparatus comprises at least one sensor for sensing measured variables, the measured variables allowing conclusions to be drawn about a surface property of the food mass, specifically corresponding to a height profile of the food mass along at least one line, in particular over the entire length and/or width of the container or of the shaft, or corresponding to the height profile of the food mass over a surface area, the sensor being a contactless sensor, which senses the surface of the food mass located in the container in a spatially resolved manner. - a container, - at least one, in particular horizontally arranged, shaft, which is equipped with tools, which are in particular arranged rotatably about the shaft axis,