A compound of Formula or a racemate, enantiomer, diastereomer or tautomer thereof: wherein R 1 and R 2 are each independently selected from the group consisting of H, halo and -CN; R 3A and R 3B are each independently selected from the group consisting of H, (C 1-6)alkyl and (C 3-7)cycloalkyl, wherein each said alkyl and cycloalkyl are optionally mono-, di-, or tri-substituted with R 32; or R 3A and R 3B, together with the C to which they are attached, are linked to form a (C 3-7)heterocyclyl or (C 3-7)cycloalkyl; wherein each said heterocyclyl and cycloalkyl are optionally mono-, di-, or tri-substituted with R 32; R 32 is each independently selected from the group consisting of halo, -CN, OH, -O-(C 1-6)alkyl, -C(=O)-(C 1-6)alkyl, (C 3-7)cycloalkyl, (C 1-6)haloalkyl and (C 1-6)alkyl optionally mono- or disubstituted with OH, CN, -O-(C 1-6)alkyl, -NH 2, -NH(C 1-6)alkyl or -N((C 1-6)alkyl) 2; Z 1 is C( R 4) or N; R 4 is H, halo, -CN, (C 1-6)alkyl, OH, -O-(C 1-6)alkyl or (C 1-6)haloalkyl; Y is -(C 1-6)alkyl- R 5, -(C 1-6)alkyl-O- R 5, -(C 1-6)alkyl-N( R 51)-(C 1-6)alkyl- R 5 or-(C 1-6)alkyl-N( R 51)- R 5; R 51 is H or (C 1-6)alkyl; R 5 is aryl, heterocyclyl or heteroaryl; wherein each said aryl, heterocyclyl and heteroaryl are optionally mono-, di-, or tri-substituted with R 52; R 52 is each independently selected from the group consisting of (C 1-6)alkyl, (C 2-6)alkenyl, -CN, - OH, -O(C 1-6)alkyl, halo, -C(=O)OH, -O-(C 1-6)alkyl, (C 3-7)cycloalkyl, -O-(C 3-7)cycloalkyl, (C 1-6)haloalkyl, -NH 2, -NH(C 1-6)alkyl, -N((C 1-6)alkyl) 2, -(C 1-6)alkyl-C(=O)OH, -(C 2-6)alkenyl-C(=O)OH, -C(=O)-O-(C 1-6)alkyl and -C(=O)-NH 2; Z 2 is C( R 6) or N; R 6 is H, halo, -CN, (C 1-6)alkyl, OH, -O-(C 1-6)alkyl or (C 1-6)haloalkyl; or a salt thereof. R 1 and R 2 are each independently selected from the group consisting of H, halo and -CN; R 3A and R 3B are each independently selected from the group consisting of H, (C 1-6)alkyl and (C 3-7)cycloalkyl, wherein each said alkyl and cycloalkyl are optionally mono-, di-, or tri-substituted with R 32; or R 3A and R 3B, together with the C to which they are attached, are linked to form a (C 3-7)heterocyclyl or (C 3-7)cycloalkyl; wherein each said heterocyclyl and cycloalkyl are optionally mono-, di-, or tri-substituted with R 32; R 32 is each independently selected from the group consisting of halo, -CN, OH, -O-(C 1-6)alkyl, -C(=O)-(C 1-6)alkyl, (C 3-7)cycloalkyl, (C 1-6)haloalkyl and (C 1-6)alkyl optionally mono- or disubstituted with OH, CN, -O-(C 1-6)alkyl, -NH 2, -NH(C 1-6)alkyl or -N((C 1-6)alkyl) 2; Z 1 is C( R 4) or N; R 4 is H, halo, -CN, (C 1-6)alkyl, OH, -O-(C 1-6)alkyl or (C 1-6)haloalkyl; R 4 is H, halo, -CN, (C 1-6)alkyl, OH, -O-(C 1-6)alkyl or (C 1-6)haloalkyl; Y is -(C 1-6)alkyl- R 5, -(C 1-6)alkyl-O- R 5, -(C 1-6)alkyl-N( R 51)-(C 1-6)alkyl- R 5 or-(C 1-6)alkyl-N( R 51)- R 5; R 51 is H or (C 1-6)alkyl; R 5 is aryl, heterocyclyl or heteroaryl; wherein each said aryl, heterocyclyl and heteroaryl are optionally mono-, di-, or tri-substituted with R 52; R 52 is each independently selected from the group consisting of (C 1-6)alkyl, (C 2-6)alkenyl, -CN, - OH, -O(C 1-6)alkyl, halo, -C(=O)OH, -O-(C 1-6)alkyl, (C 3-7)cycloalkyl, -O-(C 3-7)cycloalkyl, (C 1-6)haloalkyl, -NH 2, -NH(C 1-6)alkyl, -N((C 1-6)alkyl) 2, -(C 1-6)alkyl-C(=O)OH, -(C 2-6)alkenyl-C(=O)OH, -C(=O)-O-(C 1-6)alkyl and -C(=O)-NH 2; Z 2 is C( R 6) or N; R 6 is H, halo, -CN, (C 1-6)alkyl, OH, -O-(C 1-6)alkyl or (C 1-6)haloalkyl; R 6 is H, halo, -CN, (C 1-6)alkyl, OH, -O-(C 1-6)alkyl or (C 1-6)haloalkyl;