mhurhangee/ep-ind-claims huggingface dataset:
A plurality of AAV particles, said AAV particles (i) comprising an AAV capsid protein and a nucleic acid inserted between a pair of AAV inverted terminal repeats (ITRs), said nucleic acid encoding a polypeptide, wherein said polypeptide comprises a tripeptidylpeptidase 1 polypeptide having at least 90% identity to an amino acid sequence set forth in SEQ ID NO:5 or a pro-enzyme thereof, and (ii) being capable of transducing cells of said mammal and providing expression of said polypeptide; and a first immunosuppressive agent and a second immunosuppressive agent, for use in treating a lysosomal storage disease in a mammal, wherein the plurality of AAV particles is to be administered to the brain or spine of said mammal, wherein said first immunosuppressive agent and said second immunosuppressive agent are to be administered to said mammal, wherein said first immunosuppressive agent is cyclosporine and said second immunosuppressive agent is mycophenolate mofetil, wherein at least one of said first immunosuppressive agent and said second immunosuppressive agent are to be administered to said mammal prior to administration of said AAV particles, and wherein neutralizing antibody titer in said mammal is reduced by administration of said first immunosuppressive agent and said second immunosuppressive agent. wherein the plurality of AAV particles is to be administered to the brain or spine of said mammal, wherein said first immunosuppressive agent and said second immunosuppressive agent are to be administered to said mammal, wherein said first immunosuppressive agent is cyclosporine and said second immunosuppressive agent is mycophenolate mofetil, wherein at least one of said first immunosuppressive agent and said second immunosuppressive agent are to be administered to said mammal prior to administration of said AAV particles, and wherein neutralizing antibody titer in said mammal is reduced by administration of said first immunosuppressive agent and said second immunosuppressive agent.
A method for purifying an optically active 1-(2-trifluoromethylphenyl)ethanol represented by the formula, comprising: recrystallizing the optically active 1-(2-trifluoromethylphenyl)ethanol from an aliphatic hydrocarbon solvent where * denotes an asymmetric carbon.
Vehicle seat protected against landmines and intended for a military vehicle, with a lower part to be fixed to the military vehicle, an upper part for a seat plate of the vehicle seat, and a spring-mounted scissor frame located between the lower part and the upper part and respectively a first axis of which is permanently fixed at the lower part and the upper part and respectively a second axis of which is guided with a linear movement along a guide device provided at the lower part and the upper part, characterised in that a rack element is fixed at the second axis, associated with the lower part of the vehicle seat, of the scissor frame, and in that a pair of jaw elements held laterally at a distance from the element rack by means of a locking device of the vehicle seat, in the normal driving state of the military vehicle, are provided at the lower part next to the rack element, and in the case of a mine explosion where the height distance between the upper part and the lower part of the vehicle seat is reduced to a minimum due to the inertia of the vehicle seat occupied by a user, the locking device unlocks the jaw elements and a spring device connects the two jaw elements to the rack element by mutual engagement in form and force locking manner.
A non-woven material for use as moisture-permeable, microporous luxury food packaging, characterized in that a base web of viscous fibers pre-consolidated by water jet and without further application of bonding agents comprises a portion of fusible fibers made of thermoplastic polymer material, the non-woven material having a basis weight of 25 g/m 3 and consisting of a fiber material which comprises 70% viscous fibers and 30% polypropylene fibers.
An access point comprising: an access point body; a circuit board defining a longitudinal axis, the circuit board supported by the access point body to have a vertical orientation with respect to a supporting surface; a plurality of multi-dipole antennas (300, 300a-300f) connected to the circuit board and radially spaced from the longitudinal axis, the plurality of multi-dipole antennas (300, 300a-300f) substantially equiangularly arranged around the longitudinal axis of the circuit board; a reflector disposed on the circuit board and configured to reflect electromagnetic waves; a directional antenna connected to the circuit board and arranged adjacent to the reflector; a spectral analysis antenna connected to the circuit board and arranged vertically above the plurality of multi-dipole antennas, the spectral analysis antenna configured to measure radio energy and/or interference outside the access point body; and a spectral analysis antenna spacer disposed between the spectral analysis antenna and the plurality of multi-dipole antennas (300, 300a-300f), the spectral analysis antenna spacer configured to shield the spectral analysis antenna from interference by the plurality of multi-dipole antennas (300, 300a-300f). an access point body; a circuit board defining a longitudinal axis, the circuit board supported by the access point body to have a vertical orientation with respect to a supporting surface; a plurality of multi-dipole antennas (300, 300a-300f) connected to the circuit board and radially spaced from the longitudinal axis, the plurality of multi-dipole antennas (300, 300a-300f) substantially equiangularly arranged around the longitudinal axis of the circuit board; a reflector disposed on the circuit board and configured to reflect electromagnetic waves; a directional antenna connected to the circuit board and arranged adjacent to the reflector; a spectral analysis antenna connected to the circuit board and arranged vertically above the plurality of multi-dipole antennas, the spectral analysis antenna configured to measure radio energy and/or interference outside the access point body; and a spectral analysis antenna spacer disposed between the spectral analysis antenna and the plurality of multi-dipole antennas (300, 300a-300f), the spectral analysis antenna spacer configured to shield the spectral analysis antenna from interference by the plurality of multi-dipole antennas (300, 300a-300f).
Male piece (2; 20) for reversible and detachable connection of a dental prosthetic construction to a jawbone, said male piece (2; 20) being designed with a fastening structure by means of which the male piece (2; 20) can be fastened onto the jawbone, onto an implant that has been implanted in the jawbone, onto a tooth stump or onto a neighboring tooth, comprising: a body section (12; 120) (12; 120) having an exterior surface corresponding to a lateral surface of a cylinder, wherein the central axis of the cylinder defines a longitudinal axis (19; 190) of the male piece (2; 20); a snap-on section (11; 110), which is axially offset with respect to the longitudinal axis (19; 190) of the male piece (2; 20) relative to the body section (12; 120), said snap-on section (11; 110) comprising an exterior surface with a convex curvature along the longitudinal axis (19; 190), which protrudes outward beyond the exterior surface of the body section (12; 120) (12; 120) from the longitudinal axis (19; 190) of the male piece (2; 20); and a head end (13; 130) which axially finishs the male piece (2; 20) with respect to its longitudinal axis (19; 190), wherein the snap-on section (11; 110) is arranged closer to the head end (13; 130) than the body section (12; 120), and wherein a concave intermediate section (18; 180) is arranged between the head end (13; 130) and the convexly curved exterior surface of the snap-on section (11; 110), characterized in that the head end (13; 130) of the male piece (2; 20) is completely convexdly curved and closed. a body section (12; 120) (12; 120) having an exterior surface corresponding to a lateral surface of a cylinder, wherein the central axis of the cylinder defines a longitudinal axis (19; 190) of the male piece (2; 20); a snap-on section (11; 110), which is axially offset with respect to the longitudinal axis (19; 190) of the male piece (2; 20) relative to the body section (12; 120), said snap-on section (11; 110) comprising an exterior surface with a convex curvature along the longitudinal axis (19; 190), which protrudes outward beyond the exterior surface of the body section (12; 120) (12; 120) from the longitudinal axis (19; 190) of the male piece (2; 20); and a head end (13; 130) which axially finishs the male piece (2; 20) with respect to its longitudinal axis (19; 190), wherein the snap-on section (11; 110) is arranged closer to the head end (13; 130) than the body section (12; 120), and wherein a concave intermediate section (18; 180) is arranged between the head end (13; 130) and the convexly curved exterior surface of the snap-on section (11; 110), characterized in that the head end (13; 130) of the male piece (2; 20) is completely convexdly curved and closed.
A can container comprising: a can barrel; and a can bottom, wherein the can bottom includes a dome part which is concaved toward an inner side of the can container along a direction of a can axis at a center and also includes an annular convex part which projects toward an outer side of the can container so as to shape an annular support part on an outer periphery of the dome part, and the dome part has: a central dome part which is positioned on the can axis and has a set radius of curvature, and an outer peripheral dome part which is shaped continuously on an outer side of the central dome part, has a center of curvature positioned on the can axis, and has a radius of curvature smaller than the radius of curvature of the central dome part, and in an inner peripheral surface extending from the support part to an outer peripheral edge part of the outer peripheral dome part, the outer peripheral edge part is positioned in a direction away from the can axis to be farther from the can axis than an innermost part of the inner peripheral surface. a can barrel; and a can bottom, wherein the can bottom includes a dome part which is concaved toward an inner side of the can container along a direction of a can axis at a center and also includes an annular convex part which projects toward an outer side of the can container so as to shape an annular support part on an outer periphery of the dome part, and the dome part has: a central dome part which is positioned on the can axis and has a set radius of curvature, and an outer peripheral dome part which is shaped continuously on an outer side of the central dome part, has a center of curvature positioned on the can axis, and has a radius of curvature smaller than the radius of curvature of the central dome part, and a central dome part which is positioned on the can axis and has a set radius of curvature, and an outer peripheral dome part which is shaped continuously on an outer side of the central dome part, has a center of curvature positioned on the can axis, and has a radius of curvature smaller than the radius of curvature of the central dome part, and in an inner peripheral surface extending from the support part to an outer peripheral edge part of the outer peripheral dome part, the outer peripheral edge part is positioned in a direction away from the can axis to be farther from the can axis than an innermost part of the inner peripheral surface.
A communication system, comprising: an input interface configured to receive an input block of bits; a memory to store a prefix tree that maps a dyadic distribution of compositions of output symbols to prefixes of variable lengths, wherein a path from a root node of the prefix tree to each leaf of the prefix tree is defined by a prefix formed by a unique sequence of binary values of a length that is equal to a depth of the leaf, wherein each leaf in the prefix tree is associated with a composition that has at least a number of unique permutations equals to two in a power of a length of a suffix defined by a difference between the length of the input block of bits and the length of the prefix of the leaf; a processor configured to execute a composition selector to select a composition identified in the prefix tree by a prefix in the input block of bits and to execute a permutation mapper to permute the selected composition according to a suffix in the input block of bits; and a transmitter front end configured to transmit the permuted composition over a communication channel; characterised in that: at least some compositions in the prefix tree have multiple occurrences, and wherein each leaf is further associated with a rank offset, such that a combination of the composition with its rank offset is unique to the prefix tree, and wherein the rank offset of each leaf is equal to sum of power of two of lengths of suffixes of leafs of lower depth associated with the same composition. an input interface configured to receive an input block of bits; a memory to store a prefix tree that maps a dyadic distribution of compositions of output symbols to prefixes of variable lengths, wherein a path from a root node of the prefix tree to each leaf of the prefix tree is defined by a prefix formed by a unique sequence of binary values of a length that is equal to a depth of the leaf, wherein each leaf in the prefix tree is associated with a composition that has at least a number of unique permutations equals to two in a power of a length of a suffix defined by a difference between the length of the input block of bits and the length of the prefix of the leaf; a processor configured to execute a composition selector to select a composition identified in the prefix tree by a prefix in the input block of bits and to execute a permutation mapper to permute the selected composition according to a suffix in the input block of bits; and a transmitter front end configured to transmit the permuted composition over a communication channel; characterised in that: at least some compositions in the prefix tree have multiple occurrences, and wherein each leaf is further associated with a rank offset, such that a combination of the composition with its rank offset is unique to the prefix tree, and wherein the rank offset of each leaf is equal to sum of power of two of lengths of suffixes of leafs of lower depth associated with the same composition.
An aerosol generation device designed to operate with a consumable article, comprising: - a socket configured to receive the consumable article; - a heater arranged at least partially adjacent to the socket and configured to heat the consumable article when it is received in the socket; - at least a first sensor and a second sensor, each of the first sensor and the second sensor being configured to detect the consumable article inside at least a first portion of the socket, respectively a second portion of the socket and generate a first sensor signal (S24A), respectively a second sensor signal (S24B); - a controller configured to control the operation of the heater according to both sensor signals (S24A, S24B), wherein each sensor (24A, 24B) comprises a roller (40A, 40B) movable in rotation when the consumable article is being received in the corresponding portion (20A, 20B) of the socket or extracted from this portion (20A, 20B). - a socket configured to receive the consumable article; - a heater arranged at least partially adjacent to the socket and configured to heat the consumable article when it is received in the socket; - at least a first sensor and a second sensor, each of the first sensor and the second sensor being configured to detect the consumable article inside at least a first portion of the socket, respectively a second portion of the socket and generate a first sensor signal (S24A), respectively a second sensor signal (S24B); - a controller configured to control the operation of the heater according to both sensor signals (S24A, S24B),
A method of forming a sheet moulding compound by cutting a moulding or laminate of layers of fibrous reinforcement material preimpregnated with resin matrix (prepreg) and/or a moulding formed from resin impregnated chopped reinforcement fibers to produce one or more off-cuts (12, 14) in the form of a composite material stack (12, 14) comprising multiple elements in contact with one another, each element comprising reinforcement fibers and a resin matrix, separating the composite material stack (12, 14) into multiple combined elements and/or individual elements each comprising reinforcement fibres and a resin matrix; and randomly distributing and combining the elements to form the sheet moulding compound; wherein the method comprises the steps of temperature treating (16, 18) the composite material stack (12, 14) by heating or cooling and applying a stress to the stack (12, 14) to separate the elements.
A computing system, comprising: a computer processor; a communication system configured to communicate, through a network interface, with a first domain computing system and a second domain computing system that is different from the first domain computing system, the first and second domain computing systems (102, 104) communicating with one another through corresponding network interfaces; and an event handler orchestrator service configured to store a first event handler record corresponding to a first event handler in the first domain computing system, the first event handler record including filter criteria identifying an event of interest raised by an invoking process running on the second domain computing system, the event handler orchestrator service configured to receive a call from the invoking process when the event of interest is raised by the invoking process in the second domain computing system, the call including an event identifier identifying the raised event, and to return, to the invoking process, an endpoint in the first domain computing system, corresponding to the first event handler, for invoking the first event handler. a computer processor; a communication system configured to communicate, through a network interface, with a first domain computing system and a second domain computing system that is different from the first domain computing system, the first and second domain computing systems (102, 104) communicating with one another through corresponding network interfaces; and an event handler orchestrator service configured to store a first event handler record corresponding to a first event handler in the first domain computing system, the first event handler record including filter criteria identifying an event of interest raised by an invoking process running on the second domain computing system, the event handler orchestrator service configured to receive a call from the invoking process when the event of interest is raised by the invoking process in the second domain computing system, the call including an event identifier identifying the raised event, and to return, to the invoking process, an endpoint in the first domain computing system, corresponding to the first event handler, for invoking the first event handler.
An Electrical Discharge Machining machine comprising: a machine head; a wire guide; and a machining wire extending from said wire guide to said machine head; characterised by further comprising: a rotary table mounted to a first surface and a fixed table mounted to the rotary table; and a fixture (150;300) mounted to the fixed table, the fixture (150;300) including a mounting portion substantially circumscribing the fixture (150;300), the mounting portion further including a mounting surface (152;322), said mounting surface (152;322) being closer to the first surface than an upper surface of said fixed table, wherein the mounting portion includes a plurality of radial slots disposed about the circumference of the fixture (150;300) and a plurality of sections, each of said sections being separated from an adjacent section by one of said radial slots and each of said sections including at least one fastener feature configured to mount a clamping device. a machine head; a wire guide; and a machining wire extending from said wire guide to said machine head; characterised by further comprising: a rotary table mounted to a first surface and a fixed table mounted to the rotary table; and a fixture (150;300) mounted to the fixed table, the fixture (150;300) including a mounting portion substantially circumscribing the fixture (150;300), the mounting portion further including a mounting surface (152;322), said mounting surface (152;322) being closer to the first surface than an upper surface of said fixed table, wherein the mounting portion includes a plurality of radial slots disposed about the circumference of the fixture (150;300) and a plurality of sections, each of said sections being separated from an adjacent section by one of said radial slots and each of said sections including at least one fastener feature configured to mount a clamping device. a rotary table mounted to a first surface and a fixed table mounted to the rotary table; and a fixture (150;300) mounted to the fixed table, the fixture (150;300) including a mounting portion substantially circumscribing the fixture (150;300), the mounting portion further including a mounting surface (152;322), said mounting surface (152;322) being closer to the first surface than an upper surface of said fixed table, wherein the mounting portion includes a plurality of radial slots disposed about the circumference of the fixture (150;300) and a plurality of sections, each of said sections being separated from an adjacent section by one of said radial slots and each of said sections including at least one fastener feature configured to mount a clamping device.
An oriented film comprising a polyethylene composition which comprises: from 50 to 80 wt% of a linear low density polyethylene polymer having a density greater than 0.925 g/cc and an I 2 less than 2 g/10min; and from 50 to 20 wt% of an additional linear low density polyethylene polymer having a density lower than 0.920 g/cc and an I 2 greater than 2 g/10min; wherein the polyethylene composition has an I 2 from 0.5 to 10 g/10min and a density from 0.910 to 0.940 g/cc, wherein the oriented film is produced by a tenter frame process. from 50 to 80 wt% of a linear low density polyethylene polymer having a density greater than 0.925 g/cc and an I 2 less than 2 g/10min; and from 50 to 20 wt% of an additional linear low density polyethylene polymer having a density lower than 0.920 g/cc and an I 2 greater than 2 g/10min; wherein the polyethylene composition has an I 2 from 0.5 to 10 g/10min and a density from 0.910 to 0.940 g/cc, wherein the oriented film is produced by a tenter frame process.
An anti-reflective coating composition for use during microlithographic processes, said composition comprising a polymer and a crosslinking agent dissolved in a solvent system, said polymer being selected from the group consisting of acrylic polymers, polyesters, epoxy novolaks, polysaccharides, polyethers, polyimides, and mixtures thereof, said solvent system including a solvent selected from the group consisting of propylene glycol methyl ether acetate, propylene glycol methyl ether, propylene glycol n-propyl ether, 2-heptanone, N-methylpyrollidinone, ethyl lactate, cyclohexanone, ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, and mixtures thereof, and a weak acid, wherein said composition has a weight ratio of strong acid to weak acid of from 0:100 to 50:50, and gives a spin bowl compatibility test result of greater than 90 % when propylene glycol methyl ether is used in the spin bowl compatibility test as defined in the description of WO 02/083415 A1 on page 9, lines 2 to 28.