An image sensing module, comprising: an image sensing unit including an image sensing element having an image sensing area on the top side of the image sensing element; a light transmitting unit including a light transmitting element supported above the image sensing element by a single surrounding support body surrounding the image sensing area, wherein the light transmitting element corresponds to the image sensing area of the image sensing element, and wherein the single surrounding support body is an adhesive material made of epoxy or silicone, and the light transmitting element is firmly fixed on the image sensing element by curing the single surrounding support body; a substrate unit including a flexible substrate disposed on the image sensing element and electrically connected to the image sensing element through a plurality of electrical conductors, wherein the flexible substrate has at least one through opening for receiving the light transmitting element, and the at least one through opening corresponds to the image sensing area of the image sensing element; and a lens unit including an opaque holder disposed on the flexible substrate and the light transmitting element and a lens assembly connected to the opaque holder and disposed above the light transmitting element; wherein the image sensing element, the single surrounding support body, the light transmitting element, and the opaque holder are sequentially stacked on top of one another, wherein the image sensing area of the image sensing element is enclosed by matching the single surrounding support body and the light transmitting element for preventing the image sensing area from being polluted by external air particles, wherein the opaque holder has a surrounding support leg and at least two abutting support legs, and the bottom of the surrounding support leg for contacting an adhesive glue and the bottom of the abutting support legs for contacting the light transmitting element are separated by a distance, and the surrounding support leg is disposed on the flexible substrate through the adhesive glue, and the bottommost side of each of the at least two abutting support legs directly contact and downwardly abut against the top surface of the light transmitting element; whererin the adhesive glue is provided between the surrounding support leg and flexible substrate, and the adhesive glue does not contact the light transmitting element. an image sensing unit including an image sensing element having an image sensing area on the top side of the image sensing element; a light transmitting unit including a light transmitting element supported above the image sensing element by a single surrounding support body surrounding the image sensing area, wherein the light transmitting element corresponds to the image sensing area of the image sensing element, and wherein the single surrounding support body is an adhesive material made of epoxy or silicone, and the light transmitting element is firmly fixed on the image sensing element by curing the single surrounding support body; a substrate unit including a flexible substrate disposed on the image sensing element and electrically connected to the image sensing element through a plurality of electrical conductors, wherein the flexible substrate has at least one through opening for receiving the light transmitting element, and the at least one through opening corresponds to the image sensing area of the image sensing element; and a lens unit including an opaque holder disposed on the flexible substrate and the light transmitting element and a lens assembly connected to the opaque holder and disposed above the light transmitting element; wherein the image sensing element, the single surrounding support body, the light transmitting element, and the opaque holder are sequentially stacked on top of one another, wherein the image sensing area of the image sensing element is enclosed by matching the single surrounding support body and the light transmitting element for preventing the image sensing area from being polluted by external air particles, wherein the opaque holder has a surrounding support leg and at least two abutting support legs, and the bottom of the surrounding support leg for contacting an adhesive glue and the bottom of the abutting support legs for contacting the light transmitting element are separated by a distance, and the surrounding support leg is disposed on the flexible substrate through the adhesive glue, and the bottommost side of each of the at least two abutting support legs directly contact and downwardly abut against the top surface of the light transmitting element; whererin the adhesive glue is provided between the surrounding support leg and flexible substrate, and the adhesive glue does not contact the light transmitting element.