An ultrasonic therapy system configured to apply a non-lithotriptic acoustic radiation force to move a kidney stone, the system comprising: a therapy probe configured to generate ultrasonic exposure directed towards a therapy region, wherein the therapy probe is an ultrasonic transducer; an imaging probe configured to ultrasonically image the therapy region; a lens related to the therapy probe; and a matching layer between the transducer and the lens to transition impedance between the transducer and lens; wherein the therapy probe is configured to produce a therapy exposure comprising one or more therapy pulses over a therapy exposure time, wherein the therapy exposure has the following characteristics: a frequency of 100 kHz to 1 MHz; therapy exposure time of at least 10 ms; a peak negative pressure in the therapy region of 0.5 MPa to 5 MPa; the therapy region of one pulse defining a volume subjected to a full-width half-maximum pressure or greater and the therapy region having a length of 2 cm or greater in an axial direction and 2 mm or more in width; and the therapy region is sufficient to exert an acoustic radiation force on a kidney stone having a diameter of from 0.5 mm to 20 mm disposed within the therapy region, wherein the acoustic radiation force applied to the kidney stone is from 50 μN to 0.5 N, and wherein the acoustic radiation force is not sufficient to fragment the kidney stone. a therapy probe configured to generate ultrasonic exposure directed towards a therapy region, wherein the therapy probe is an ultrasonic transducer; an imaging probe configured to ultrasonically image the therapy region; a lens related to the therapy probe; and a matching layer between the transducer and the lens to transition impedance between the transducer and lens; wherein the therapy probe is configured to produce a therapy exposure comprising one or more therapy pulses over a therapy exposure time, wherein the therapy exposure has the following characteristics: a frequency of 100 kHz to 1 MHz; therapy exposure time of at least 10 ms; a peak negative pressure in the therapy region of 0.5 MPa to 5 MPa; the therapy region of one pulse defining a volume subjected to a full-width half-maximum pressure or greater and the therapy region having a length of 2 cm or greater in an axial direction and 2 mm or more in width; and the therapy region is sufficient to exert an acoustic radiation force on a kidney stone having a diameter of from 0.5 mm to 20 mm disposed within the therapy region, wherein the acoustic radiation force applied to the kidney stone is from 50 μN to 0.5 N, and wherein the acoustic radiation force is not sufficient to fragment the kidney stone. a frequency of 100 kHz to 1 MHz; therapy exposure time of at least 10 ms; a peak negative pressure in the therapy region of 0.5 MPa to 5 MPa; the therapy region of one pulse defining a volume subjected to a full-width half-maximum pressure or greater and the therapy region having a length of 2 cm or greater in an axial direction and 2 mm or more in width; and the therapy region is sufficient to exert an acoustic radiation force on a kidney stone having a diameter of from 0.5 mm to 20 mm disposed within the therapy region, wherein the acoustic radiation force applied to the kidney stone is from 50 μN to 0.5 N, and wherein the acoustic radiation force is not sufficient to fragment the kidney stone.