mhurhangee/ep-ind-claims huggingface dataset:
A method for identifying a modulator of Sirt5 demalonylase or desuccinylase activity, comprising: providing a candidate compound; providing a substrate comprising a malonyl or succinyl lysine linked to an indicator moiety; contacting the substrate with Sirt5 in the presence of the candidate compound under conditions for Sirt5 to demalonylate or desuccinylate the substrate; contacting the demalonylated or desuccinylated substrate with a cleavage agent that cleaves the linkage between the lysine and the indicator moiety to release the indicator moiety, thereby generating a detectable signal; and correlating signal intensity with Sirt5 demalonylase or desuccinylase activity; wherein a change in Sirt5 demalonylase or desuccinylase activity in the presence of the candidate compound, relative to Sirt5 demalonylase or desuccinylase activity in the absence of the candidate compound, identifies the candidate compound as a modulator of Sirt5 demalonylase or desuccinylase activity. providing a candidate compound; providing a substrate comprising a malonyl or succinyl lysine linked to an indicator moiety; contacting the substrate with Sirt5 in the presence of the candidate compound under conditions for Sirt5 to demalonylate or desuccinylate the substrate; contacting the demalonylated or desuccinylated substrate with a cleavage agent that cleaves the linkage between the lysine and the indicator moiety to release the indicator moiety, thereby generating a detectable signal; and correlating signal intensity with Sirt5 demalonylase or desuccinylase activity;
Hemostatic composition comprising: a) a biocompatible polymer in particulate form suitable for use in hemostasis, wherein the biocompatible polymer is a crosslinked gelatin and wherein the particles have a median size of 10 to 1000 μm, and b) one hydrophilic polymeric component comprising reactive groups, wherein the presence of a hydrophilic polymeric component with nucleophilic reactive groups is excluded; wherein said hydrophilic polymeric component is a hydrophilic crosslinker with electrophilic reactive groups and wherein the biocompatible polymer and the hydrophilic polymeric crosslinker are present in a solid matrix. a) a biocompatible polymer in particulate form suitable for use in hemostasis, wherein the biocompatible polymer is a crosslinked gelatin and wherein the particles have a median size of 10 to 1000 μm, and b) one hydrophilic polymeric component comprising reactive groups, wherein the presence of a hydrophilic polymeric component with nucleophilic reactive groups is excluded;
A communication proxy method, comprising: receiving, by a communication proxy device, a packet communicated between a provider device and an access device; obtaining, by the communication proxy device, mapping information between a physical port of an access device and a logic port of the communication proxy device, converting, by the communication proxy device, the physical port in the received packet to the corresponding logic port or converting the logic port in the received packet to the corresponding physical port according to the mapping information between a physical port of the access device and a logic port used in the provider device, wherein the mapping information comprises a physical port ID of the physical port and a logic port ID of the logic port; and sending, by the communication proxy device, the packet after the conversion process. receiving, by a communication proxy device, a packet communicated between a provider device and an access device; obtaining, by the communication proxy device, mapping information between a physical port of an access device and a logic port of the communication proxy device, converting, by the communication proxy device, the physical port in the received packet to the corresponding logic port or converting the logic port in the received packet to the corresponding physical port according to the mapping information between a physical port of the access device and a logic port used in the provider device, wherein the mapping information comprises a physical port ID of the physical port and a logic port ID of the logic port; and sending, by the communication proxy device, the packet after the conversion process.
A method for managing data storage and access on a computing device, the computing device associated with at least a first storage system and a second storage system, the method comprising the steps of: a) providing a unified file system interface for facilitating interaction with the computing device, the unified file system interface configured to facilitate interaction with content of both the first storage system and the second storage system, the unified file system interface comprising alias files accessible via an alias file path structure; and b) managing storage of content across the first storage system and the second storage system in accordance with a rule set, wherein managing storage of content comprises moving files between the first storage system and the second storage system; the method further comprising the steps of providing associations between each alias file of the alias file path structure and corresponding content of the first storage system or the second storage system, wherein the alias file path structure is independent of locations of corresponding content of the first storage system and the second storage system, and wherein the alias file path structure is unaffected by said moving files between the first storage system and the second storage system. a) providing a unified file system interface for facilitating interaction with the computing device, the unified file system interface configured to facilitate interaction with content of both the first storage system and the second storage system, the unified file system interface comprising alias files accessible via an alias file path structure; and b) managing storage of content across the first storage system and the second storage system in accordance with a rule set, wherein managing storage of content comprises moving files between the first storage system and the second storage system;
Process for the preparation of a compound of general formula: or respectively of a compound of general formula: in which R symbolizes one or more optional substituents, x, y is equal to 0 or 1 with (x+y) equal to 1 or 2, which consists in reacting, in the vapor phase, ammonia with a compound of general formula: or respectively with a compound of general formula: in which R 1 and R 2, which are identical or different, represent-OR 3, R 3 being an alkyl group having from 1 to 4 carbon atoms, in the presence of a catalyst comprising a silicon orthophosphate of formula Si 3 (PO 4) 4. in which R symbolizes one or more optional substituents, x, y is equal to 0 or 1 with (x+y) equal to 1 or 2, which consists in reacting, in the vapor phase, ammonia with a compound of general formula: or respectively with a compound of general formula: in which R 1 and R 2, which are identical or different, represent-OR 3, R 3 being an alkyl group having from 1 to 4 carbon atoms, in the presence of a catalyst comprising a silicon orthophosphate of formula Si 3 (PO 4) 4. in which R 1 and R 2, which are identical or different, represent-OR 3, R 3 being an alkyl group having from 1 to 4 carbon atoms, in the presence of a catalyst comprising a silicon orthophosphate of formula Si 3 (PO 4) 4.
A modular element for the manufacture of chains for jewellery and costume jewellery articles, said modular element comprising a component having a body with a hole and a connection element extending integrally from said body on the side opposite to said hole, said connection element having a rounded head placed on a neck of reduced diameter, said modular element further comprising an insert consisting of a substantially cylindrical base from which emerges a frusto-conical portion provided, on the side opposite to said base, with a central hole, extending inside the insert, and with at least two grooves that form through slits in the walls of said frusto-conical portion and divide said walls in as many lugs, said insert being adapted to snap receive said connection element so that said rounded head may be locked inside said central hole letting said body free to rotate around said neck, said insert being further adapted to be snap inserted inside a hole of another analogous modular element.
An image sensor comprising: an array of photo-sensitive regions (PSRs) for accumulating photocharge in response to incident light; and associated with at least a first PSR of the PSRs, an output channel comprising: a first sense node for converting photocharge into voltage, a first capacitance control unit connected to the first sense node, wherein the first capacitance control unit comprises two reset transistors (210, 220) in series and a second sense node connected therebetween, connected to the first sense node, a first amplification circuit having a first transconductance, and connected to the second sense node, a second amplification circuit coupled to a second output signal line and having a second transconductance characterized in that said second transconductance is larger than said first transconductance. an array of photo-sensitive regions (PSRs) for accumulating photocharge in response to incident light; and associated with at least a first PSR of the PSRs, an output channel comprising: a first sense node for converting photocharge into voltage, a first capacitance control unit connected to the first sense node, wherein the first capacitance control unit comprises two reset transistors (210, 220) in series and a second sense node connected therebetween, connected to the first sense node, a first amplification circuit having a first transconductance, and connected to the second sense node, a second amplification circuit coupled to a second output signal line and having a second transconductance characterized in that said second transconductance is larger than said first transconductance. a first sense node for converting photocharge into voltage, a first capacitance control unit connected to the first sense node, wherein the first capacitance control unit comprises two reset transistors (210, 220) in series and a second sense node connected therebetween, connected to the first sense node, a first amplification circuit having a first transconductance, and connected to the second sense node, a second amplification circuit coupled to a second output signal line and having a second transconductance characterized in that said second transconductance is larger than said first transconductance.
Method for restoring license keys (PK1,...,PK10) in a modular automation station comprising a main unit with a backplane bus connection and a plurality of modules (M1,...,M6) similarly with a backplane bus connection, wherein the modules (M1,...,M6) or the main unit with the respective backplane bus connection communicate with one another via a backplane bus, wherein the modules (M1,...,M6) are operated by means of a license key (PK1,...,PK10) to provide a software-based functionality (F1,...,F10) tied to the respective license key (PK1,...,PK10), wherein after a module is replaced with a replacement module, in which the software-based functionality is not yet enabled, a restoration step is carried out, characterised in that a license key set is restored, wherein the license key set comprises all license keys (PK1,...,PK10) of the modules (M1,...,M6) of the automation station, for restoring the license key set, a first data block is read from a first storage location of the automation station, a second data block is read from a second storage location of the automation station and a third data block is read from a third storage location of the automation station, wherein the data blocks (1,2,3) comprise data portions (Da,Db) of the license key set as follows, the license key set is divided into a first part and a second part, wherein parity information (P1,P2,P3,P4) is formed from the two parts (A,B) and the data portions (Da,Db) and the parity information (P1,P2,P3,P4) are distributed in a balanced manner over the data blocks (1,2,3), wherein the license key set is restored on the basis of the parity information even if only two of the three data blocks (1,2,3) could be read and the license key for the software-based functionality of the replaced module is assigned to the replacement module and thus the software-based functionality is enabled for the replacement module.
An interface seal assembly for sealing a tubular filter element relative to a first component of a fluid filtration system and a second component of the fluid filtration system, the interface seal assembly comprising: an interface body which is adapted to be positioned between the first component and the second component of the fluid filtration system, the interface body comprising: an aperture extending through the interface body, for communicating with an internal cavity of the tubular filter element; a first mounting surface comprising a first seal groove; and a second mounting surface opposite the first mounting surface, the second mounting surface comprising a second seal groove; in which one of the first and second seal grooves has a circular shape in plan view, and the other one of the first and second seal grooves has a non-circular shape in plan view; a first seal located in the first seal groove, for sealing the interface body relative to one of the first and second components; and a second seal located in the second seal groove, for sealing the interface body relative to the other one of the first and second components. an interface body which is adapted to be positioned between the first component and the second component of the fluid filtration system, the interface body comprising: an aperture extending through the interface body, for communicating with an internal cavity of the tubular filter element; a first mounting surface comprising a first seal groove; and a second mounting surface opposite the first mounting surface, the second mounting surface comprising a second seal groove; in which one of the first and second seal grooves has a circular shape in plan view, and the other one of the first and second seal grooves has a non-circular shape in plan view; an aperture extending through the interface body, for communicating with an internal cavity of the tubular filter element; a first mounting surface comprising a first seal groove; and a second mounting surface opposite the first mounting surface, the second mounting surface comprising a second seal groove; in which one of the first and second seal grooves has a circular shape in plan view, and the other one of the first and second seal grooves has a non-circular shape in plan view; a first seal located in the first seal groove, for sealing the interface body relative to one of the first and second components; and a second seal located in the second seal groove, for sealing the interface body relative to the other one of the first and second components.
Packaging container constructed as a pot, consisting substantially of an inner part and a casing-shaped outer part, wherein the inner part forms a dish-shaped or pot-shaped container and the outer part at least partly surrounds the inner part, wherein the inner part is constructed in single-part or multi-part form from a mouldable, particularly thermoformable and/or deep-drawable material, wherein apart from conventional plastics materials also a material produced from renewable, biologically degradable and/or recycled raw materials can be provided at least in part as the material and wherein the outer part at least partly surrounds the circumference of the inner part and apart from conventional materials is preferably produced from a renewable, biologically degradable and/or recycled raw material, wherein preferably materials with fibre content are provided, wherein at least the inner part has at its upper or open end an edge, which is rolled as seen in cross-section, and wherein the cross-section of the edge represents a circle or a section of a circle, characterised in that the rolled edge has at its upper side a flat region, wherein a sealing seam between pot and a cover foil or a lid, which is capable of closing the pot, can be arranged in this flat region.
A method for constructing a robotic arm comprising a plurality of links and a rope assembly, wherein the links further include a plurality of brackets, the method comprising: providing the rope assembly having a rope with a plurality of rope bearings threaded thereon, wherein the rope is capable of controlling the movement of the robotic arm by increasing and/or decreasing tension on the rope; and attaching the plurality of rope bearings of the rope assembly to the plurality of links of the robotic arm, wherein attaching the plurality of rope bearings of the rope assembly to the plurality of links of the robotic arm comprises removably coupling the plurality of rope bearings of the rope assembly to the plurality of links of the robotic arm, via the plurality of brackets of the links. providing the rope assembly having a rope with a plurality of rope bearings threaded thereon, wherein the rope is capable of controlling the movement of the robotic arm by increasing and/or decreasing tension on the rope; and attaching the plurality of rope bearings of the rope assembly to the plurality of links of the robotic arm, wherein attaching the plurality of rope bearings of the rope assembly to the plurality of links of the robotic arm comprises removably coupling the plurality of rope bearings of the rope assembly to the plurality of links of the robotic arm, via the plurality of brackets of the links.
Crankshaft for an in-line internal combustion engine with at least two bearing points and a number of crank throws (36, 38, 40, 42; 56, 58, 60, 62 64, 66), wherein the crank throws (36, 38, 40, 42; 56, 58, 60, 62 64, 66) are arranged angularly offset with respect to each other such that at least two crank throws (36, 42; 56, 66) are provided in angular coincidence with each other, and wherein the crank throws (36, 38, 40, 42; 56, 58, 60, 62 64, 66) are associated with counter-weight elements for mass balance, the first and the last crank throw (36, 42; 56, 66), seen in the axial direction of the crankshaft, being provided in angular coincidence with each other, wherein the counter-weight elements (44, 46, 48, 50) of the first and the last crank throw have additional weights (52, 54), characterized in that the additional weights (52, 54) are arranged in a mirrored manner, seen in the axial direction.
A hair conditioning composition comprising a) A cationic surfactant; b) An antidandruff agent selected from climbazole, ketoconazole, or octopirox; and c) from 0.01 to 5.0% by weight of octyldodecanol; wherein the composition comprises less than 1% silicone compound, preferably less than 0.1% silicone compound by weight of the composition. a) A cationic surfactant; b) An antidandruff agent selected from climbazole, ketoconazole, or octopirox; and c) from 0.01 to 5.0% by weight of octyldodecanol;
A method for controlling a wireless ear bud (105, 110), the method comprising: responsive to detecting an input to answer an incoming voice call: when the wireless ear bud is configured in an active microphone state and connected to a companion communication device via a voice profile, answering the incoming voice call via the companion communication device; and when the wireless ear bud is configured in a muted microphone state and connected to the companion communication device via a non-voice profile: re-configuring the wireless ear bud from the muted microphone state to the active microphone state; changing connection of the wireless ear bud to the companion communication device from using the non-voice profile to using a voice profile; and answering the incoming voice call via the wireless ear bud while in the active microphone state and via the companion communication device to which the wireless ear bud is directly connected using the voice profile. when the wireless ear bud is configured in an active microphone state and connected to a companion communication device via a voice profile, answering the incoming voice call via the companion communication device; and when the wireless ear bud is configured in a muted microphone state and connected to the companion communication device via a non-voice profile: re-configuring the wireless ear bud from the muted microphone state to the active microphone state; changing connection of the wireless ear bud to the companion communication device from using the non-voice profile to using a voice profile; and answering the incoming voice call via the wireless ear bud while in the active microphone state and via the companion communication device to which the wireless ear bud is directly connected using the voice profile. re-configuring the wireless ear bud from the muted microphone state to the active microphone state; changing connection of the wireless ear bud to the companion communication device from using the non-voice profile to using a voice profile; and answering the incoming voice call via the wireless ear bud while in the active microphone state and via the companion communication device to which the wireless ear bud is directly connected using the voice profile.
A profiled article comprising a profile region with profiled surface, where a covering material has been applied on the profiled surface, and that area of the covering material that faces away from the profiled surface has a sealing layer made of a reactive melt, wherein the profile region comprises a profile geometry with several profile radii, characterized in that at least one profile radius is smaller than 3 mm and the covering material has a thickness of at most 200 to 400 μm.
A method of wireless communication, the method comprising: communicating a first set of broadcast reference signals, RSs, in a first subframe that includes a synchronization, SYNC, channel; and communicating a second set of broadcast RSs in a second subframe that follows the first subframe, wherein the first set and the second set of broadcast RSs are configured for channel estimation for decoding a master information block, MIB, in the SYNC channel. communicating a first set of broadcast reference signals, RSs, in a first subframe that includes a synchronization, SYNC, channel; and communicating a second set of broadcast RSs in a second subframe that follows the first subframe, wherein the first set and the second set of broadcast RSs are configured for channel estimation for decoding a master information block, MIB, in the SYNC channel.