Three-dimensionally aggregated, phospholipid-based nanometric vesicles dispersed in an alcoholic mixture, comprising or consisting of: a) at least one phospholipid selected among one or more natural or synthetic phospholipids, whether pure or blended, selected from the group including soy or egg lecithin, phosphatidylcholine at different degrees of purity, whether hydrogenated or non-hydrogenated, phosphatidylethanolamine, phosphatidylserine, phosphatidylglycero1, phosphatidylinosito1, dimyristoylphosphatidylcholine, dipalmitoylphosphatidylcholine, distearoylphosphatidylcholine, sphyngomyelin, palmitoylstearoylphosphatidylcholine, hydrogenated and non-hydrogenated phospholipids derived from soy and/or mixtures thereof; b) at least one pharmaceutical and/or cosmetic active principle, one biologically active molecule of natural or synthetic origin, and/or one natural extract of vegetable or animal origin, and/or a mixture thereof; c) a dispersing carrier miscible with water, consisting of a mixture of alcohols and/or polyalcohols and/or glycols and/or polyglycols and/or polyoxyethylenes and a quantity of water of 0 to 25% (v/v), relative to the total volume of said dispersing carrier; d) additives such as modifying agents and/or surfactants and/or preserving agents and/or a mixture thereof; wherein the components of said vesicles are present in the quantities specified in the following tables (wherein the sum of the single components adds up to 100%): a) -Composition of the nanovesicles Phospholipids Active principles Natural extracts or substances Modifiers and/or surfactants Preservatives Dispersing carrier (% w/v) (% w/v) (% w/v) (% w/v) (% w/v) (% w/v) 1 - 45 0 - 10 0 - 10 0 - 10 0 - 1 60 - 99 b) - Composition of the aqueous dispersing carrier Alcohols (% v/v) Glycols (% v/v) Polyalcohols or polyoxyethylene s (% v/v) Water (% v/v) 0 - 70 0 - 70 0 - 70 0 - 25 a) at least one phospholipid selected among one or more natural or synthetic phospholipids, whether pure or blended, selected from the group including soy or egg lecithin, phosphatidylcholine at different degrees of purity, whether hydrogenated or non-hydrogenated, phosphatidylethanolamine, phosphatidylserine, phosphatidylglycero1, phosphatidylinosito1, dimyristoylphosphatidylcholine, dipalmitoylphosphatidylcholine, distearoylphosphatidylcholine, sphyngomyelin, palmitoylstearoylphosphatidylcholine, hydrogenated and non-hydrogenated phospholipids derived from soy and/or mixtures thereof; b) at least one pharmaceutical and/or cosmetic active principle, one biologically active molecule of natural or synthetic origin, and/or one natural extract of vegetable or animal origin, and/or a mixture thereof; c) a dispersing carrier miscible with water, consisting of a mixture of alcohols and/or polyalcohols and/or glycols and/or polyglycols and/or polyoxyethylenes and a quantity of water of 0 to 25% (v/v), relative to the total volume of said dispersing carrier; d) additives such as modifying agents and/or surfactants and/or preserving agents and/or a mixture thereof; wherein the components of said vesicles are present in the quantities specified in the following tables (wherein the sum of the single components adds up to 100%): a) -Composition of the nanovesicles Phospholipids Active principles Natural extracts or substances Modifiers and/or surfactants Preservatives Dispersing carrier (% w/v) (% w/v) (% w/v) (% w/v) (% w/v) (% w/v) 1 - 45 0 - 10 0 - 10 0 - 10 0 - 1 60 - 99 b) - Composition of the aqueous dispersing carrier Alcohols (% v/v) Glycols (% v/v) Polyalcohols or polyoxyethylene s (% v/v) Water (% v/v) 0 - 70 0 - 70 0 - 70 0 - 25