mhurhangee/ep-ind-claims huggingface dataset:
Air centrifugation device, associated to an internal combustion engine, which comprises at least one cylinder, provided with air by an air intake, and rejecting combustion gases by an exhaust orifice, the said air centrifugation device comprising a wheel, mounted on an axle and placed inside an envelope containing the said wheel, the said envelope having preferably a circular shape, the whole system comprising at least one air intake orifice and at feast two distinct exhaust orifices and, provided to collect separately the oxygen molecules from exhaust orifice, on the one hand, and the nitrogen molecules from exhaust orifice, on the other hand, while at least one connecting pipe is provided between the oxygen exhaust orifice and the air inlet system of the internal combustion engine, being characterized by: - the said wheel comprises blades, designed according to the state of the art, intended to accelerate the gases by a rotational movement, the axle of wheel being driven at a very high rotation speed, by the means of a turbine placed in line with some elements of the exhaust system of the internal combustion engine, - the air intake orifice is placed near the central part of envelope of the said air centrifugation device, while the exhaust orifice provided to collect the oxygen is located on envelope, at a position near the periphery of the wheel, whereas the exhaust orifice provided to evacuate the nitrogen is also located on envelope, but at an intermediate position between the axis of wheel and the periphery of said wheel; and - the shape of envelope, for the part located near the periphery of wheel, comprises a wider cross section, allowing to generate a strip of gas of an appropriate thickness to obtain optimal oxygen concentration. - the said wheel comprises blades, designed according to the state of the art, intended to accelerate the gases by a rotational movement, the axle of wheel being driven at a very high rotation speed, by the means of a turbine placed in line with some elements of the exhaust system of the internal combustion engine, - the air intake orifice is placed near the central part of envelope of the said air centrifugation device, while the exhaust orifice provided to collect the oxygen is located on envelope, at a position near the periphery of the wheel, whereas the exhaust orifice provided to evacuate the nitrogen is also located on envelope, but at an intermediate position between the axis of wheel and the periphery of said wheel; and - the shape of envelope, for the part located near the periphery of wheel, comprises a wider cross section, allowing to generate a strip of gas of an appropriate thickness to obtain optimal oxygen concentration.
( Currently Amended) An improved process for the preparation of fluvoxamine maleate of formula I, comprising the steps of: a) condensing the compound of formula II, with hydroxylamine hydrochloride in organic solvent selected from alcohol, ketone, nitrile, hydrocarbons or mixtures thereof, with improvement comprising the reaction is conducted in the presence of sodium carbonate granules at temperature 45-50°C to form a compound of formula III; b) isolating compound of formula III; c) treating compound of formula III with 2-chloroethylamine hydrochloride in the presence of base in solvent with improvement comprising the reaction is conducted at temperature 40-45°C to form compound of formula IV; d) extracting compound of formula IV with solvent to form an organic layer; e) treating organic layer of step d) with maleic acid; f) isolating crude fluvoxamine maleate of formula I; and g) optionally purifying fluvoxamine maleate of formula I a) condensing the compound of formula II, with hydroxylamine hydrochloride in organic solvent selected from alcohol, ketone, nitrile, hydrocarbons or mixtures thereof, with improvement comprising the reaction is conducted in the presence of sodium carbonate granules at temperature 45-50°C to form a compound of formula III; b) isolating compound of formula III; c) treating compound of formula III with 2-chloroethylamine hydrochloride in the presence of base in solvent with improvement comprising the reaction is conducted at temperature 40-45°C to form compound of formula IV; d) extracting compound of formula IV with solvent to form an organic layer; e) treating organic layer of step d) with maleic acid; f) isolating crude fluvoxamine maleate of formula I; and g) optionally purifying fluvoxamine maleate of formula I
A compound having formula: or a pharmaceutically acceptable salt thereof, wherein: X is-(CH 2) n -; n is 1; R 1 is selected from the group consisting of C 1-6 alkyl and substituted C 1-6 alkyl; R 2 is selected from the group consisting of an amino acid, an N-substituted amino acid, -C(=O)-Y-(CR 3 R 4) m -NR 5 R 6 and -C(=O)-O-(CR 3 R 4) m -O-C(=O)-R 10; Y is -O- or a bond; R 2 ' is selected from the group consisting of H, C 1 -C 6 alkyl, and substituted C 1 -C 6 alkyl; each R 3 and R 4 are independently H, C 1 -C 6 alkyl, substituted C 1 -C 6 alkyl, aryl, substituted aryl, -(CR 3 R 4) m -NR 5 R 6, or m is an integer selected from the group consisting of 1, 2, 3, 4, 5, 6, 7, and 8; R 5 and R 6 are independently H or alkyl; and Rio is selected from the group consisting of alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, monosaccharide, acylated monosaccharide, aryl, substituted aryl, heteroaryl, and substituted heteroaryl, for use in treating cancer, wherein the compound having formula is to be administered with immune checkpoint blockade therapy, adoptive cellular therapy, or an adenosine A2aR inhibitor. X is-(CH 2) n -; n is 1; R 1 is selected from the group consisting of C 1-6 alkyl and substituted C 1-6 alkyl; R 2 is selected from the group consisting of an amino acid, an N-substituted amino acid, -C(=O)-Y-(CR 3 R 4) m -NR 5 R 6 and -C(=O)-O-(CR 3 R 4) m -O-C(=O)-R 10; Y is -O- or a bond; R 2 ' is selected from the group consisting of H, C 1 -C 6 alkyl, and substituted C 1 -C 6 alkyl; each R 3 and R 4 are independently H, C 1 -C 6 alkyl, substituted C 1 -C 6 alkyl, aryl, substituted aryl, -(CR 3 R 4) m -NR 5 R 6, or m is an integer selected from the group consisting of 1, 2, 3, 4, 5, 6, 7, and 8; R 5 and R 6 are independently H or alkyl; and Rio is selected from the group consisting of alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, monosaccharide, acylated monosaccharide, aryl, substituted aryl, heteroaryl, and substituted heteroaryl, for use in treating cancer, wherein the compound having formula is to be administered with immune checkpoint blockade therapy, adoptive cellular therapy, or an adenosine A2aR inhibitor.
A retaining member, comprising: a body portion having an innermost surface, an outermost surface, a first side and a second side; wherein said innermost surface of said body portion of said retaining member has a first arcuate portion having a first end and a second end; wherein said outermost surface of said body portion of said retaining member has a second arcuate portion having a first end and a second end; wherein said first side of said body portion of said retaining member has a first substantially flat portion having a first end and a second end; wherein said second side of said body portion of said retaining member has a second substantially flat portion having a first end and a second end; and wherein said first end of said first arcuate portion of said body portion of said retaining member is directly connected to said first end of said first substantially flat portion of said retaining member and said second end of said first arcuate portion is directly connected to a first end of said second substantially flat portion of said retaining member; and wherein said first end of said second arcuate portion of said body portion of said retaining member is directly connected to said second end of said first substantially flat portion of said retaining member and said second end of said second arcuate portion is directly connected to a second end of said second substantially flat portion of said retaining member. a body portion having an innermost surface, an outermost surface, a first side and a second side; wherein said innermost surface of said body portion of said retaining member has a first arcuate portion having a first end and a second end; wherein said outermost surface of said body portion of said retaining member has a second arcuate portion having a first end and a second end; wherein said first side of said body portion of said retaining member has a first substantially flat portion having a first end and a second end; wherein said second side of said body portion of said retaining member has a second substantially flat portion having a first end and a second end; and wherein said first end of said first arcuate portion of said body portion of said retaining member is directly connected to said first end of said first substantially flat portion of said retaining member and said second end of said first arcuate portion is directly connected to a first end of said second substantially flat portion of said retaining member; and wherein said first end of said second arcuate portion of said body portion of said retaining member is directly connected to said second end of said first substantially flat portion of said retaining member and said second end of said second arcuate portion is directly connected to a second end of said second substantially flat portion of said retaining member.
A method of operating a vehicle control unit, VCU, the method comprising: calculating a speed variation of a vehicle corresponding to each point on a path of the vehicle based on respective input information associated with the each point, wherein the input information comprises any one or any combination of weather information, traffic flow information, or road type information; predicting an average speed of the vehicle at the each point on the path of the vehicle based on the calculated speed variation corresponding to the each point and reference speed information of the each point; generating a first speed profile based on the predicted average speed for the each point on the path of the vehicle; said method characterised by the further steps of generating a second speed profile by applying additive white Gaussian noise to the first speed profile; and determining driving related information of the vehicle based on the second speed profile. calculating a speed variation of a vehicle corresponding to each point on a path of the vehicle based on respective input information associated with the each point, wherein the input information comprises any one or any combination of weather information, traffic flow information, or road type information; predicting an average speed of the vehicle at the each point on the path of the vehicle based on the calculated speed variation corresponding to the each point and reference speed information of the each point; generating a first speed profile based on the predicted average speed for the each point on the path of the vehicle; said method characterised by the further steps of generating a second speed profile by applying additive white Gaussian noise to the first speed profile; and determining driving related information of the vehicle based on the second speed profile.
Target device configured to be attested by an appraiser by remote attestation, the target device comprising a Virtual Machine Manager, VMM, running one or more virtual machines, and being configured to: - receive from the appraiser an attestation request, - collect (602, 603) virtual machine attestation information (vPCR, vSML) about the one or more virtual machines, - generate a virtual machine integrity value by concatenating at least part of the collected virtual machine attestation information (vPCR), - generate a digital signature (Quote(PCR, H) AIK) for the VVM based on the virtual machine integrity value, and - send the generated digital signature (Quote(PCR, H) AIK) and the virtual machine attestation information (vPCR, vSML) to the appraiser as a response to the attestation request, wherein the target device further comprises - a security module (509, TPM) configured to generate the digital signature (Quote(PCR, H) AIK) for the VMM, wherein the digital signature (Quote(PCR, H) AIK) is generated based on the virtual machine integrity value and on a memory register value corresponding to the security module, the memory register value including at least one measurement of the VMM wherein the target device is further configured to: - generate a VMM measurement report, the VMM measurement report comprising at least one VMM measurement, and - send the VMM measurement report to the appraiser along with the generated digital signature (Quote(PCR, H) AIK) and the virtual machine attestation information (vPCR, vSML). - receive from the appraiser an attestation request, - collect (602, 603) virtual machine attestation information (vPCR, vSML) about the one or more virtual machines, - generate a virtual machine integrity value by concatenating at least part of the collected virtual machine attestation information (vPCR), - generate a digital signature (Quote(PCR, H) AIK) for the VVM based on the virtual machine integrity value, and - send the generated digital signature (Quote(PCR, H) AIK) and the virtual machine attestation information (vPCR, vSML) to the appraiser as a response to the attestation request, wherein the target device further comprises - a security module (509, TPM) configured to generate the digital signature (Quote(PCR, H) AIK) for the VMM, - generate a VMM measurement report, the VMM measurement report comprising at least one VMM measurement, and - send the VMM measurement report to the appraiser along with the generated digital signature (Quote(PCR, H) AIK) and the virtual machine attestation information (vPCR, vSML).
A sol-like composition for producing a nucleic acid gel which does not contain a nucleic acid linking enzyme, the composition containing a mixture of two or more oligonucleotides composed of a cohesive protruding end moiety and a complementary base sequence moiety in the composition at a nucleic acid concentration of 0.3 mM + 1.6/x (the number of bases in the protruding end moiety) mM or less, not containing a nucleic acid linking enzyme, and having a salt concentration of 80 mM/x (the number of bases in the protruding end moiety) or less in terms of a NaCl concentration, wherein the cohesive protruding end moiety is a single strand nucleic acid moiety having 4 or more nucleotide length and being complementary to a cohesive protruding end moiety in at least another oligonucleotide to such a degree as to form a double strand sequence showing a melting temperature that is equal to or higher than the body temperature in a physiological condition, and the complementary base sequence moiety that binds to the other oligonucleotide in a complementary manner has 8 or more nucleotide length and is complementary to the complementary base sequence moiety in the other oligonucleotide to such a degree as to form a double strand sequence showing a melting temperature that is equal to or higher than the body temperature in a physiological condition.
A method, in an anchor base station, for establishing a second link between a wireless terminal and an assisting base station, where the wireless terminal is served by the anchor base station via a first link, the method comprising: identifying the assisting base station for establishing the second link with the wireless terminal; negotiating random access parameters with the assisting base station; and sending, to the wireless terminal, an attach request message to establish the second link between the wireless terminal and the assisting base station, wherein the attach request message comprises the negotiated random access parameters. identifying the assisting base station for establishing the second link with the wireless terminal; negotiating random access parameters with the assisting base station; and sending, to the wireless terminal, an attach request message to establish the second link between the wireless terminal and the assisting base station, wherein the attach request message comprises the negotiated random access parameters.
A separating device for a mold used to produce a molded article in a molding cavity intended to allow the separation between at least one part of the molded article and at least one part of said molding cavity, said device comprising: - an actuating device translatable along a first axis between a retracted position and a separated position, - at least one separating element (28, 60) translatable along a second axis, different from the first axis, between a retracted position and a separated position, - at least one transfer device connecting the actuating device and the separating element (28, 60), said transfer device being arranged to move the separating element (28, 60) along the second axis between its retracted position and its separated position when the actuating device is moved along the first axis between its retracted position and its separated position, characterized in that the transfer device comprises at least two links, rotatable relative to one another and relative to the actuating device and the separating element (28, 60), and a guide element receiving said links, said links being moved along a movement path in said guide element by the actuating device and moving the separating element (28, 60), said links being guided in said guide element over the entire movement path. - an actuating device translatable along a first axis between a retracted position and a separated position, - at least one separating element (28, 60) translatable along a second axis, different from the first axis, between a retracted position and a separated position, - at least one transfer device connecting the actuating device and the separating element (28, 60), said transfer device being arranged to move the separating element (28, 60) along the second axis between its retracted position and its separated position when the actuating device is moved along the first axis between its retracted position and its separated position,
Vane for a turbine engine stator, comprising: - a body in the form of an aerodynamic profile formed by a shell produced from a composite material formed by a three-dimensional textile of reinforcement fibres consolidated by a hardened resin, the shell forming a pressure surface of the vane and a suction surface of the vane connected to each other while forming, on one side, a leading edge of the vane, and on the opposite side a trailing edge of the vane, and - a core comprising a core body in the form of an aerodynamic profile surrounded by the shell, characterised in that the core is produced from a non-porous plastics material, and the core body delimits at least one closed cavity (68; 68A-68D) of the core. - a body in the form of an aerodynamic profile formed by a shell produced from a composite material formed by a three-dimensional textile of reinforcement fibres consolidated by a hardened resin, the shell forming a pressure surface of the vane and a suction surface of the vane connected to each other while forming, on one side, a leading edge of the vane, and on the opposite side a trailing edge of the vane, and - a core comprising a core body in the form of an aerodynamic profile surrounded by the shell,
A rod assembly comprising a rod; a first bearing assembly attached to a first end of the rod and a second bearing assembly attached to a second end of the rod, where each of the first and second bearing assembly (234, 236) comprises: an outer bearing member defining a cavity; an inner bearing member disposed within the cavity, the inner bearing member including: a spherical surface; and a rod attachment opening defined in the spherical surface; and an elastomeric material disposed within the cavity adjacent to the spherical surface; wherein the inner bearing member and the outer bearing member are capable of relative angular rotation with respect to each other. a rod; a first bearing assembly attached to a first end of the rod and a second bearing assembly attached to a second end of the rod, where each of the first and second bearing assembly (234, 236) comprises: an outer bearing member defining a cavity; an inner bearing member disposed within the cavity, the inner bearing member including: a spherical surface; and a rod attachment opening defined in the spherical surface; and an elastomeric material disposed within the cavity adjacent to the spherical surface; wherein the inner bearing member and the outer bearing member are capable of relative angular rotation with respect to each other. an outer bearing member defining a cavity; an inner bearing member disposed within the cavity, the inner bearing member including: a spherical surface; and a rod attachment opening defined in the spherical surface; and a spherical surface; and a rod attachment opening defined in the spherical surface; and an elastomeric material disposed within the cavity adjacent to the spherical surface; wherein the inner bearing member and the outer bearing member are capable of relative angular rotation with respect to each other.
An ophthalmologic information processing apparatus comprising: an acquisition unit configured to acquire a tomographic image of a subject's eye formed based on scan data acquired using an optical system for performing optical coherence tomography on the subject's eye; a tissue specifying unit configured to acquire first shape data representing shape of a tissue of the subject's eye by performing segmentation processing on the tomographic image, the first shape data including a high sensitivity component and a low sensitivity component, the high sensitivity component having a large variation for a change in a position of the optical system with respect to the subject's eye, the low sensitivity component having a small variation for the change in the position of the optical system with respect to the subject's eye; characterised by a specifying unit configured to specify the low sensitivity component from the first shape data, and to output the specified low sensitivity component as second shape data representing shape of the tissue. an acquisition unit configured to acquire a tomographic image of a subject's eye formed based on scan data acquired using an optical system for performing optical coherence tomography on the subject's eye; a tissue specifying unit configured to acquire first shape data representing shape of a tissue of the subject's eye by performing segmentation processing on the tomographic image, the first shape data including a high sensitivity component and a low sensitivity component, the high sensitivity component having a large variation for a change in a position of the optical system with respect to the subject's eye, the low sensitivity component having a small variation for the change in the position of the optical system with respect to the subject's eye; characterised by a specifying unit configured to specify the low sensitivity component from the first shape data, and to output the specified low sensitivity component as second shape data representing shape of the tissue.