mhurhangee/ep-ind-claims huggingface dataset:
A cytomegalovirus IL-10 protein selected from: (i) a cytomegalovirus IL-10 protein as depicted in SEQ ID NO:3, or consisting of the amino acid sequence or a homologue thereof having at least 90% identity therewith characterized by an amino acid substitution at one or more of K58, Q62, E160 and D162, wherein the numbering is according to SEQ ID NO:3; (ii) a cytomegalovirus IL-10 protein as depicted in SEQ ID NO:1 or SEQ ID NO:2 or a homologue thereof having at least 90% identity therewith characterized by an amino acid substitution at one or more of R63, Q67, E174 and D176, wherein the numbering is according to of SEQ ID NO:1, preferably by an amino acid substitution at one or more of Q67R, R63E, E174Q and D176H, more preferably by amino acid substitutions at Q67R and D176H or by amino acid substitutions at E174Q and D176H, wherein the amino acid substitution(s) result(s) in a phenotype of reduced binding to an interleukin-10 (IL-10) receptor protein and retained immunogenicity as compared to a cytomegalovirus IL-10 protein lacking said substitution(s). (i) a cytomegalovirus IL-10 protein as depicted in SEQ ID NO:3, or consisting of the amino acid sequence or a homologue thereof having at least 90% identity therewith characterized by an amino acid substitution at one or more of K58, Q62, E160 and D162, wherein the numbering is according to SEQ ID NO:3; (ii) a cytomegalovirus IL-10 protein as depicted in SEQ ID NO:1 or SEQ ID NO:2 or a homologue thereof having at least 90% identity therewith characterized by an amino acid substitution at one or more of R63, Q67, E174 and D176, wherein the numbering is according to of SEQ ID NO:1, preferably by an amino acid substitution at one or more of Q67R, R63E, E174Q and D176H, more preferably by amino acid substitutions at Q67R and D176H or by amino acid substitutions at E174Q and D176H, wherein the amino acid substitution(s) result(s) in a phenotype of reduced binding to an interleukin-10 (IL-10) receptor protein and retained immunogenicity as compared to a cytomegalovirus IL-10 protein lacking said substitution(s).
Conveyor device for the automated conveyance of individual products in a direction of conveyance, the conveyor device being configured as an overhead conveyor device which comprises a. several adapters with in each case one adapter identification means for accommodating the individual products, b. an adapter data reading unit for reading adapter data of the adapter identification means, c. a carrier conveyor for carrying transport of the individual products, d. wherein the carrier conveyor has a plurality of carriers for carrying in each case one adapter along the direction of conveyance, characterised in that e. each individual product has an individual product transponder, f. a transponder reading unit is provided for reading individual product data of the individual product transponder g. a control unit is provided, which is in signal communication with the transponder reading unit and the adapter data reading unit for linking the individual product data read by means of the transponder reading unit with the adapter data read by means of the adapter data reading unit, h. the transponder reading unit is arranged in the region of the carrier conveyor, i. a carrier distance (a, a 1, a 2) between two adjacent carriers is variably adjustable in the direction of conveyance, wherein various carrier distances (a 1, a 2) are adjustable in a predefined manner by means of a carrier spacer grid, j. a separating unit is provided for separating and releasing the adapters for further transport to the carrier conveyor in a defined manner. a. several adapters with in each case one adapter identification means for accommodating the individual products, b. an adapter data reading unit for reading adapter data of the adapter identification means, c. a carrier conveyor for carrying transport of the individual products, d. wherein the carrier conveyor has a plurality of carriers for carrying in each case one adapter along the direction of conveyance, characterised in that e. each individual product has an individual product transponder, f. a transponder reading unit is provided for reading individual product data of the individual product transponder g. a control unit is provided, which is in signal communication with the transponder reading unit and the adapter data reading unit for linking the individual product data read by means of the transponder reading unit with the adapter data read by means of the adapter data reading unit, h. the transponder reading unit is arranged in the region of the carrier conveyor, i. a carrier distance (a, a 1, a 2) between two adjacent carriers is variably adjustable in the direction of conveyance, wherein various carrier distances (a 1, a 2) are adjustable in a predefined manner by means of a carrier spacer grid, j. a separating unit is provided for separating and releasing the adapters for further transport to the carrier conveyor in a defined manner.
An abnormality detection system of an internal combustion engine in which an exhaust purification catalyst is arranged in an engine exhaust passage, a hydrocarbon feed valve is arranged in the engine exhaust passage upstream of the exhaust purification catalyst, wherein the exhaust purification catalyst is comprised of a straight flow type catalyst having a plurality of exhaust flow paths which extend in a longitudinal axial direction of the exhaust purification catalyst, and a limited partial region where deposition of particulate in the exhaust gas may cause clogging at a peripheral portion of an upstream side end face of the exhaust purification catalyst is predicted in advance as a particulate deposition region, with an air-fuel ratio sensor arranged downstream of a peripheral portion of a downstream side end face of the exhaust purification catalyst in an exhaust gas flow region corresponding to the downstream side of the particulate deposition region when viewed along a longitudinal axis of the exhaust purification catalyst, and in which when an air-fuel ratio of an exhaust gas flowing into the exhaust purification catalyst is made to instantaneously change, if deposition of particulate in the exhaust gas causes clogging at the particulate deposition region in the peripheral portion of the upstream side end face of the exhaust purification catalyst, a speed of change of an output value of the air-fuel ratio sensor falls compared with when deposition of the particulate does not cause clogging, a control means being adapted such that the air-fuel ratio of the exhaust gas flowing into the exhaust purification catalyst is made to instantaneously change and, when the speed of change of the output value of the air-fuel ratio sensor falls at this time, it is judged that deposition of particulate in the exhaust gas causes clogging at the particulate deposition region in the peripheral portion of the upstream side end face of the exhaust purification catalyst.
A port status synchronization method, wherein a physical layer PHY device and a link layer MAC device are connected by using a service interface, and the method comprises: determining, by the PHY device or an external processor connected to the PHY device, whether a first service interface of the PHY device changes; characterized in that if the first service interface of the PHY device changes, controlling, by the PHY device or the external processor, a second service interface of the PHY device to restart auto-negotiation; and sending, by using the second service interface, an auto-negotiation advertisement packet to a first device connected to the second service interface, so as to trigger the first device to synchronize, according to the auto-negotiation advertisement packet, a status of the second service interface and a status of the first service interface, wherein the auto-negotiation advertisement packet comprises status information of the first service interface; wherein the first device is the MAC device, the PHY device and the MAC device are connected by using the second service interface, the PHY device and a peer device are connected by using the first service interface, the peer device comprises a second PHY device and a second MAC device; or the first device is a peer device, the PHY device and the MAC device are connected by using the first service interface, the PHY device and the peer device are connected by using the second service interface, the peer device comprises a second PHY device and a second MAC device. determining, by the PHY device or an external processor connected to the PHY device, whether a first service interface of the PHY device changes; characterized in that if the first service interface of the PHY device changes, controlling, by the PHY device or the external processor, a second service interface of the PHY device to restart auto-negotiation; and sending, by using the second service interface, an auto-negotiation advertisement packet to a first device connected to the second service interface, so as to trigger the first device to synchronize, according to the auto-negotiation advertisement packet, a status of the second service interface and a status of the first service interface, wherein the auto-negotiation advertisement packet comprises status information of the first service interface; wherein the first device is the MAC device, the PHY device and the MAC device are connected by using the second service interface, the PHY device and a peer device are connected by using the first service interface, the peer device comprises a second PHY device and a second MAC device; or the first device is a peer device, the PHY device and the MAC device are connected by using the first service interface, the PHY device and the peer device are connected by using the second service interface, the peer device comprises a second PHY device and a second MAC device.
Sliding device for a vehicle seat, which sliding device comprises a pair of parallel slideways (3a, 3b), each comprising a lower rail (5a, 5b), an upper rail (7a, 7b), that is slidably mounted to said lower rail, and a latch (21a, 21b), which is arranged between said lower rail and said upper rail and selectively allows / prevents movement of the upper rail relative to the lower rail, wherein in a rest condition said latches (21a, 21b) are in a locking position, in which they prevent the movement of the upper rails relative to the lower rails, and wherein the sliding device comprises a releasing member for driving said latches to an unlocking position in which they allow the movement of the upper rails relative to the lower rails, wherein said releasing member is made as a "U"-shaped releasing handle comprising a middle gripping portion and two substantially parallel arms (29a, 29b) wherein each of said latches (21a, 21b) comprises a front portion (23a, 23b) and a rear portion (25a, 25b) joined by an intermediate portion (27a, 27b), wherein said front portion (23a, 23b) is fixed to the respective upper rail (7a, 7b) and said rear portion (25a, 25b) is bent into a "U" shape comprising a lower leg (31a, 31b) and an upper leg (33a, 33b), joined by a curved, vertically oriented section (35a, 35b), wherein latching elements (37a, 37b) are configured to cooperate with corresponding latching elements (41a, 41b) provided in said lower rails (5a, 5b) are provided in said lower leg (31a, 31b) of said rear portion of said latch, characterized in that said upper leg (33a, 33b) of said rear portion of said latch is configured to engage said releasing member and is provided with engaging elements (43a, 43b) configured to cooperate with engaging elements (45a, 45b) provided at respective end portions of said arms (29a, 29b) of said releasing handle.
A system (100, 300, 400) comprising: one or more icepacks (108, 500, 700); a garment that includes one or more pockets (106, 206) configured to receive the one or more icepacks (108, 500, 700); and at least one shoulder strap (204, 304, 404) disposed over a shoulder region of the garment, the at least one shoulder strap (204, 304, 404) comprising at least a first end; characterized in that each of the one or more icepacks (108, 500, 700) includes at least a first aperture (510, 710); and in that the first end of the at least one shoulder strap (204, 304, 404) is configured to pass through the first aperture (510, 710) of the one or more icepacks (108, 500, 700) to secure the at least one shoulder strap (204, 304, 404) to the one or more icepacks (108, 500, 700). one or more icepacks (108, 500, 700); a garment that includes one or more pockets (106, 206) configured to receive the one or more icepacks (108, 500, 700); and at least one shoulder strap (204, 304, 404) disposed over a shoulder region of the garment, the at least one shoulder strap (204, 304, 404) comprising at least a first end; characterized in that each of the one or more icepacks (108, 500, 700) includes at least a first aperture (510, 710); and in that the first end of the at least one shoulder strap (204, 304, 404) is configured to pass through the first aperture (510, 710) of the one or more icepacks (108, 500, 700) to secure the at least one shoulder strap (204, 304, 404) to the one or more icepacks (108, 500, 700).
A method for automatically white balancing a digital image, comprising: in response to a white balancing trigger, adjusting relative positions of an image sensor and a reference region having a color suitable for white balancing such that the image sensor is positioned to acquire an image of the reference region; acquiring the image of the reference region using the image sensor; and computing a parameter for white balancing the digital image from the image of the reference region, wherein said adjusting comprises automatically moving the image sensor such that the reference region is within the field-of-vision of the image sensor, wherein said adjusting comprises enabling the image sensor to scan surroundings of the image sensor to locate the reference region. in response to a white balancing trigger, adjusting relative positions of an image sensor and a reference region having a color suitable for white balancing such that the image sensor is positioned to acquire an image of the reference region; acquiring the image of the reference region using the image sensor; and computing a parameter for white balancing the digital image from the image of the reference region, wherein said adjusting comprises automatically moving the image sensor such that the reference region is within the field-of-vision of the image sensor, wherein said adjusting comprises enabling the image sensor to scan surroundings of the image sensor to locate the reference region.
A method for enabling a home gateway to be managed by multiple servers, characterized by comprising: receiving, by the home gateway, configuration information sent by a first server, wherein the configuration information comprises at least information about an address of a second server and rights of the second server; generating, by the home gateway, a virtual device according to the configuration information, wherein the rights of the second server is used for setting the rights of the second server; receiving, by the home gateway, management information from the second server; and managing, by the second server, the virtual device according to the management information after setting up a connection between the virtual device and the second server, wherein the address of the second server is used for setting up the connection between the virtual device and the second server, wherein the virtual device comprises all or part of parameters of the home gateway, and has all or part of functions of the home gateway. receiving, by the home gateway, configuration information sent by a first server, wherein the configuration information comprises at least information about an address of a second server and rights of the second server; generating, by the home gateway, a virtual device according to the configuration information, wherein the rights of the second server is used for setting the rights of the second server; receiving, by the home gateway, management information from the second server; and managing, by the second server, the virtual device according to the management information after setting up a connection between the virtual device and the second server, wherein the address of the second server is used for setting up the connection between the virtual device and the second server, wherein the virtual device comprises all or part of parameters of the home gateway, and has all or part of functions of the home gateway.
Compositions stimulating the expression of Sirtuin 1, selected from combinations of: - Berberine and tyrosol; - Tyrosol and ferulic acid. - Berberine and tyrosol; - Tyrosol and ferulic acid.
Device to regulate the relative humidity level in a CPV module which can comprise at least one module unit (5,6,...), the device comprising a desiccant unit connectable to the module via a duct, and to ambient atmosphere, the device being characterised in that the device comprises a switching mechanism (4, 9) which is actuated by a regulation unit based on thermodynamic parameters directly related to condensation, allowing a gas flow to the module from either the desiccant unit or ambient atmosphere.
A laryngeal mask comprising an airway tube having an inner lumen following a predetermined curve in a central mirror symmetry plane about which the inner lumen is generally mirror symmetrical, an outer surface, a proximal end and a distal end, a mask portion being arranged around the airway tube at the distal end thereof, the inner lumen of the airway tube thus communicating with or forming a mask lumen in said mask portion, said mask portion comprising a circumferential cuff comprising an inflatable inner volume delimited by a closed tubular wall, arranged at the periphery of the mask portion and generally surrounding said mask lumen, the circumferential cuff having a shape presenting a tip part at the distal end of laryngeal mask, a gastric tube which extends at least partially along the outer surface of the airway tube, penetrates through said closed tubular wall at a first location, extends through said inflatable volume, and ends in a connection to an opening in the closed tubular wall at a second location at the tip part so as to provide a passage through said circumferential cuff, where, with respect to said central mirror symmetry plane said gastric tube extends along the outer surface of the airway tube in an asymmetrical manner, through said closed tubular wall at a first location arranged asymmetrically with respect to a central plane, through said inflatable volume, and ends in a connection to the closed tubular wall at a second location at the tip part so as to provide a passage through said circumferential cuff, characterized in that said first location is arranged at the back of the tubular cuff and asymmetrical with respect to a central plane of the mask portion.
A handheld medical ultrasound imaging device comprising: a plurality of hand held transducer assemblies (22, 104), each transducer assembly including a probe housing, a transducer array, and a cable with a first transducer connector; a hand held portable processing unit (26, 50, 122, 200, 240, 250) connectable to each of the hand held transducer assemblies (22, 104) with the cable and the first transducer connector at one of one or more connectors on the processing unit, the processing unit having an integrated touch screen display (106, 202) configured to display an ultrasound image wherein the display is mounted integral with a processor operative in response to the integrated touch screen display, a memory system, a battery, and an ultrasound beamformer processing circuit (118, 208) wherein the touch screen display and the ultrasound beamformer processing circuit are communicably connected to the processor, the processor being operative in response to finger operation of the integrated touch screen display to operate a graphical user interface configured to display the selectable types of transducer assemblies and corresponding transducer parameters upon connection of the transducer assembly (22, 104)on the touch screen display, wherein the portable processing unit further comprises a plurality of computer programs including a scan conversion program, a Doppler processing program and a transducer identification program. a plurality of hand held transducer assemblies (22, 104), each transducer assembly including a probe housing, a transducer array, and a cable with a first transducer connector; a hand held portable processing unit (26, 50, 122, 200, 240, 250) connectable to each of the hand held transducer assemblies (22, 104) with the cable and the first transducer connector at one of one or more connectors on the processing unit, the processing unit having an integrated touch screen display (106, 202) configured to display an ultrasound image wherein the display is mounted integral with a processor operative in response to the integrated touch screen display, a memory system, a battery, and an ultrasound beamformer processing circuit (118, 208) wherein the touch screen display and the ultrasound beamformer processing circuit are communicably connected to the processor, the processor being operative in response to finger operation of the integrated touch screen display to operate a graphical user interface configured to display the selectable types of transducer assemblies and corresponding transducer parameters upon connection of the transducer assembly (22, 104)on the touch screen display, wherein the portable processing unit further comprises a plurality of computer programs including a scan conversion program, a Doppler processing program and a transducer identification program.
A device for implanting a prosthesis in a body tissue, comprising a tubular element having an open end through which the prosthesis can exit outward; a pressure element acting on a rear end of the prosthesis; first movement means programmed for advancing the pressure element inside the tubular element so as to bring a front end of the prosthesis closer to the open end and second movement means programmed for moving the tubular element back with respect to the pressure element a pre-established calculated amount, in a manner such that the rear end of the prosthesis exits outward from the open end; wherein the device also comprises a control unit for controlling said first movement means and second movement means so as to allow to precisely program a travel of the first movement means and of the second movement means and, consequently, of the pressure element and of the tubular element, and wherein said first movement means are programmed for advancing the pressure element inside the tubular element along a path such to bring the front end of the prosthesis to a pre-established distance from the open end, said second movement means being programmed for moving the tubular element back an amount that is equal to a longitudinal size of the prosthesis, plus said pre-established distance.