mhurhangee/ep-ind-claims huggingface dataset:
A heart valve repair or replacement device comprising: a) a substrate comprising a plurality of spaces; b) a silane linkage material contacted to the substrate; and c) a low profile composite covering in conformal contact with the substrate and suturelessly attached to the substrate, the low profile composite covering comprising: i) a textile fabric layer heat-stabilized into the shape of the substrate; and ii) a thermoplastic polymer coating integrated with the textile fabric layer to form the composite covering, the thermoplastic polymer coating or select portions thereof being substantially fluid impermeable, d) wherein the composite covering is in conformal contact with at least some of the inner and outer substrate surfaces and with itself through at least some of the plurality of spaces in the substrate. a) a substrate comprising a plurality of spaces; b) a silane linkage material contacted to the substrate; and c) a low profile composite covering in conformal contact with the substrate and suturelessly attached to the substrate, the low profile composite covering comprising: i) a textile fabric layer heat-stabilized into the shape of the substrate; and ii) a thermoplastic polymer coating integrated with the textile fabric layer to form the composite covering, the thermoplastic polymer coating or select portions thereof being substantially fluid impermeable, i) a textile fabric layer heat-stabilized into the shape of the substrate; and ii) a thermoplastic polymer coating integrated with the textile fabric layer to form the composite covering, the thermoplastic polymer coating or select portions thereof being substantially fluid impermeable, d) wherein the composite covering is in conformal contact with at least some of the inner and outer substrate surfaces and with itself through at least some of the plurality of spaces in the substrate.
A method comprising: causing, at least in part, a default display of selectable objects (403, 405, 407, 409, 411, 413, 415, 417) in motion travelling across a graphical user interface, wherein the selectable objects are displayed based on a category of selectable object or context dependent data and wherein each of the selectable objects corresponds to data or an application accessible via the graphical user interface; and allowing user selection and manipulation of the selectable objects displayed on the graphical user interface, by transforming a selectable object into a source (419, 503) by activating the selectable object, by the user positioning the selectable object into a defined location of the graphical user interface so that the source produces a flow, in a direction across the display, of content that is associated with the selectable object. causing, at least in part, a default display of selectable objects (403, 405, 407, 409, 411, 413, 415, 417) in motion travelling across a graphical user interface, wherein the selectable objects are displayed based on a category of selectable object or context dependent data and wherein each of the selectable objects corresponds to data or an application accessible via the graphical user interface; and allowing user selection and manipulation of the selectable objects displayed on the graphical user interface, by transforming a selectable object into a source (419, 503) by activating the selectable object, by the user positioning the selectable object into a defined location of the graphical user interface so that the source produces a flow, in a direction across the display, of content that is associated with the selectable object.
A vertical axis turbine including: a base; and a turbine rotor (F, S, H) rotatable relative to the base about a vertical axis of rotation, wherein the turbine rotor comprises: a hub rotatably mounted to the base; and at least two inclined elongate aerofoil or hydrofoil spars mounted at respective lower ends thereof to the hub, and inclined upwardly and outwardly relative to the vertical axis of rotation; a respective aerofoil or hydrofoil section blade is fixed to each one of said spars, and each aerofoil or hydrofoil section blade is inclined downwardly and outwardly relative to the vertical axis of rotation, and characterised in that: each aerofoil or hydrofoil section blade is mounted so as to generate aerodynamic or hydrodynamic lift forces which counteract an overturning moment generated by the spars when the turbine is operating in a fluid flow. a base; and a turbine rotor (F, S, H) rotatable relative to the base about a vertical axis of rotation, wherein the turbine rotor comprises: a hub rotatably mounted to the base; and at least two inclined elongate aerofoil or hydrofoil spars mounted at respective lower ends thereof to the hub, and inclined upwardly and outwardly relative to the vertical axis of rotation; a respective aerofoil or hydrofoil section blade is fixed to each one of said spars, and each aerofoil or hydrofoil section blade is inclined downwardly and outwardly relative to the vertical axis of rotation, and characterised in that: each aerofoil or hydrofoil section blade is mounted so as to generate aerodynamic or hydrodynamic lift forces which counteract an overturning moment generated by the spars when the turbine is operating in a fluid flow. a hub rotatably mounted to the base; and at least two inclined elongate aerofoil or hydrofoil spars mounted at respective lower ends thereof to the hub, and inclined upwardly and outwardly relative to the vertical axis of rotation; a respective aerofoil or hydrofoil section blade is fixed to each one of said spars, and each aerofoil or hydrofoil section blade is inclined downwardly and outwardly relative to the vertical axis of rotation, and characterised in that: each aerofoil or hydrofoil section blade is mounted so as to generate aerodynamic or hydrodynamic lift forces which counteract an overturning moment generated by the spars when the turbine is operating in a fluid flow. each aerofoil or hydrofoil section blade is mounted so as to generate aerodynamic or hydrodynamic lift forces which counteract an overturning moment generated by the spars when the turbine is operating in a fluid flow.
A multi-target compound with anticoagulation and platelet GPIIb/IIIa receptor antagonism, said compound having a structure as shown in Formula: A-L-B-L'-C Formula wherein A and B are thrombin binding sites, C is a platelet GPIIb/IIIa receptor binding site, L is a first linker, and L' is a second linker, wherein L' has a structure as shown in Formula: ((Gly) n1 -(Ser) n2) n3 Formula wherein n1 is 1, 2, 3 or 4; n2 is 0 or 1; and n3 is 0, 1, 2 or 3; or L' has a structure as shown in Formula: (Glu-Ala-Ala-Ala-Lys) n1 Formula wherein n1 is 0, 1, 2 or 3, or L' has a structure as shown in Formula: (Arg-Val-Leu-Ala-Glu-Ala) n1 Formula wherein n1 is 0, 1, 2 or 3; wherein A has a structure as shown in Formula: A1-A2-A3-A4 Formula wherein A1 is D-Phe; A2 is Pro or Pip; A3 is Arg, Lys, Orn or Har; and A4 is Pro, D-Pro or Ser; wherein B has a structure as shown in Formula: B1-B2-B3-B4-B5 Formula wherein B1 is a dipeptide consisting of any two acidic amino acids; B2 is Val, Leu, Ile, Nle or Phe; B3 is Hyp, Ser, Pro or an N-methyl amino acid; B4 is a dipeptide consisting of any two acidic amino acids; and B5 is an amino acid selected from the group consisting of Tyr, Trp, Phe, Leu, Nle, Ile, Val, Cha and Pro, or B5 is a dipeptide comprising at least one amino acid selected from Tyr, Trp, Phe, Leu, Nle, Ile, Val, Cha and Pro; wherein C has a structure as shown in Formula: Cys-Har-C1-Asp-Trp-Pro-C2 Formula wherein C1 is Gly or Ser; C2 is Cys or a structure obtained by replacing -OH in Cys with -NH 2; and a disulfide bond is formed between two mercapto groups in the Formula; wherein L has a structure as shown in Formula: L1-L2-L3-L4-Gly-Asp-L5 Formula wherein L1 is Gly, Ala, Val or Gly-Gly; L2 is Gly or Cys; L3 is Gly, Gly-Gly, Gly-Gly-Gly or a dextrorotatory amino acid; L4 is Asn or Gln; L5 is one selected from Phe, Tyr, a derivative in which a benzene ring of Phe is substituted, and a derivative in which a benzene ring of Tyr is substituted. wherein B1 is a dipeptide consisting of any two acidic amino acids; B2 is Val, Leu, Ile, Nle or Phe; B3 is Hyp, Ser, Pro or an N-methyl amino acid; B4 is a dipeptide consisting of any two acidic amino acids; and B5 is an amino acid selected from the group consisting of Tyr, Trp, Phe, Leu, Nle, Ile, Val, Cha and Pro, or B5 is a dipeptide comprising at least one amino acid selected from Tyr, Trp, Phe, Leu, Nle, Ile, Val, Cha and Pro;
A gastro-jejunal (G-J) feeding device including: a gastro-jejunal body including a top portion a bottom portion and a balloon port,, the bottom portion configured to abut a patient's skin, the top portion of the G-J body provided with a gastric port leading to a gastric channel and a jejunal port leading to jejunal channel; and an integral feeding tube including a tubular portion having multiple lumens including a proximal end and a distal end, the proximal end operatively connected to the bottom portion of the gastro-jejunal body, the multiple lumen, integral feeding tube including: a gastric lumen configured to be in fluid communication with the gastric channel and extending from the proximal end to an intermediate portion of the integral feeding tube: a jejunal lumen configured to be in fluid communication with the jejunal channel and extending from the proximal end to the distal end: and a balloon lumen configured to be in fluid communication with the balloon port, wherein the gastric lumen jejunal lumen and balloon lumen share a common separating wall that divides the passageway of the feeding tube, with the jejunal lumen positioned on one side of the separating wall and the gastric and balloon lumen positioned on the other side of the separating wall. a gastro-jejunal body including a top portion a bottom portion and a balloon port,, the bottom portion configured to abut a patient's skin, the top portion of the G-J body provided with a gastric port leading to a gastric channel and a jejunal port leading to jejunal channel; and an integral feeding tube including a tubular portion having multiple lumens including a proximal end and a distal end, the proximal end operatively connected to the bottom portion of the gastro-jejunal body, the multiple lumen, integral feeding tube including: a gastric lumen configured to be in fluid communication with the gastric channel and extending from the proximal end to an intermediate portion of the integral feeding tube: a jejunal lumen configured to be in fluid communication with the jejunal channel and extending from the proximal end to the distal end: and a balloon lumen configured to be in fluid communication with the balloon port, a gastric lumen configured to be in fluid communication with the gastric channel and extending from the proximal end to an intermediate portion of the integral feeding tube: a jejunal lumen configured to be in fluid communication with the jejunal channel and extending from the proximal end to the distal end: and a balloon lumen configured to be in fluid communication with the balloon port, a jejunal lumen configured to be in fluid communication with the jejunal channel and extending from the proximal end to the distal end: and a balloon lumen configured to be in fluid communication with the balloon port, wherein the gastric lumen jejunal lumen and balloon lumen share a common separating wall that divides the passageway of the feeding tube, with the jejunal lumen positioned on one side of the separating wall and the gastric and balloon lumen positioned on the other side of the separating wall.
A method for setting a pitch angle of a rotor blade for a rotor of a wind turbine, in particular for avoiding suction-side flow separation, wherein the rotor blade is movable rotationally about a rotor blade longitudinal axis for setting the pitch angle by means of a pitch drive (116, 314), comprising the steps: - determining an aerodynamic power of the rotor, - establishing a nominal pitch angle as a function of the aerodynamic power, and - setting the pitch angle to the established nominal pitch angle, characterized in that the nominal pitch angle is established on the basis of an aerodynamic power factor depicted in a portionally linear control function, wherein the portions of the portionally linear control function are defined by the aerodynamic power. - determining an aerodynamic power of the rotor, - establishing a nominal pitch angle as a function of the aerodynamic power, and - setting the pitch angle to the established nominal pitch angle,
A flow access apparatus (10, 150, 300, 602) for a flow system in a subsea oil and gas production installation, the flow access apparatus comprising: a body (12, 312); a plurality of connectors (20a, 20b, 322, 320) configured to connect the apparatus to the flow system; and a flow access interface (18, 118, 318) for connecting the apparatus to a subsea process apparatus; wherein the flow access interface (18, 118, 318) provides a single connection point and/or landing point for the subsea process apparatus; wherein the body defines a plurality of flow paths (15, 17, 115, 117, 315, 317, 615, 617), and each flow path fluidly connects one of the plurality of connectors to the flow access interface to provide an intervention path from a connected subsea process apparatus to the flow system in use; and wherein the apparatus is configured to be disposed between a flow line connector for a jumper flow line and a jumper flow line to provide access points for the flow system and an access point to the jumper flowline from a connected subsea process apparatus in use. a body (12, 312); a plurality of connectors (20a, 20b, 322, 320) configured to connect the apparatus to the flow system; and a flow access interface (18, 118, 318) for connecting the apparatus to a subsea process apparatus; wherein the flow access interface (18, 118, 318) provides a single connection point and/or landing point for the subsea process apparatus; wherein the body defines a plurality of flow paths (15, 17, 115, 117, 315, 317, 615, 617), and each flow path fluidly connects one of the plurality of connectors to the flow access interface to provide an intervention path from a connected subsea process apparatus to the flow system in use; and wherein the apparatus is configured to be disposed between a flow line connector for a jumper flow line and a jumper flow line to provide access points for the flow system and an access point to the jumper flowline from a connected subsea process apparatus in use.
An oral care implement comprising a head including a first surface and a cleanser for soft tissue in the mouth, the cleanser including a plurality of projections protruding outward from the first surface for removal of microbial and other debris from soft tissue in the mouth, the projections including a peripheral wall protruding from the first surface and an end surface remote from the first surface, the end surface being inclined to the first surface to define an outermost projecting edge along one portion of the peripheral wall; characterised in that each of the projections is a cylindrical shape or a conical shape.
A main switch arrangement for a residual current safety switch, characterized in that the arrangement comprises: - a main shaft movable in the vertical direction and a trip part arranged essentially around the main shaft, which trip part is adapted to turn around the main shaft, - an actuator and a summation current transformer connected electrically to it, which actuator is arranged essentially in connection with the trip part, - at least one return spring (8, 9), and - a contact module, - wherein the main shaft, trip part, return spring (8, 9) and actuator are arranged in such a way that in a fault current situation a protrusion projecting from the actuator is adapted to push the trip part and to bring about a rotational motion in the trip part, and wherein the rotational motion of the trip part is further adapted to release the spring force formed by the return spring (8, 9), said spring force lifting the main shaft and/or lowering the contact module, in such a way that the contact module of the main switch in connection with the main shaft displaces into an electrically non-conductive state. - a main shaft movable in the vertical direction and a trip part arranged essentially around the main shaft, which trip part is adapted to turn around the main shaft, - an actuator and a summation current transformer connected electrically to it, which actuator is arranged essentially in connection with the trip part, - at least one return spring (8, 9), and - a contact module, - wherein the main shaft, trip part, return spring (8, 9) and actuator are arranged in such a way that in a fault current situation a protrusion projecting from the actuator is adapted to push the trip part and to bring about a rotational motion in the trip part, and wherein the rotational motion of the trip part is further adapted to release the spring force formed by the return spring (8, 9), said spring force lifting the main shaft and/or lowering the contact module, in such a way that the contact module of the main switch in connection with the main shaft displaces into an electrically non-conductive state.
Method for manufacturing a pharmaceutically active hyperbranched polyester polyol derivative, comprising the following steps: a) reacting only glycidol and e-caprolactone in a molar ratio between glycidol and ε-caprolactone between 1:1 and 10:1 in the presence of a catalyst at a temperature lying in a range of between 40 °C and 140 °C to obtain a hyperbranched polyester polyol in which caprolactone residues and glycerol residues are randomly arranged, b) reacting the hyperbranched polyester polyol of step a) with a sulfation reagent to obtain a sulfated hyperbranched polyester polyol as hyperbranched polyester polyol derivative. a) reacting only glycidol and e-caprolactone in a molar ratio between glycidol and ε-caprolactone between 1:1 and 10:1 in the presence of a catalyst at a temperature lying in a range of between 40 °C and 140 °C to obtain a hyperbranched polyester polyol in which caprolactone residues and glycerol residues are randomly arranged, b) reacting the hyperbranched polyester polyol of step a) with a sulfation reagent to obtain a sulfated hyperbranched polyester polyol as hyperbranched polyester polyol derivative.
Sound generator (1; 1'; 1") for an active noise control system for a vehicle with internal combustion engine, wherein the sound generator (1; 1'; 1") comprises: - a first casing with at least one exhaust gas inlet and at least one exhaust gas outlet different from the at least one exhaust gas inlet; and - at least one electro-acoustical transducer that is configured to produce sound in dependence on an electrical control signal; wherein the at least one electro-acoustical transducer is directly attached to the first casing, wherein the first casing comprises a hole or plural holes at the position of the at least one electro-acoustical transducer, the electro-acoustical transducer covering the hole or holes in the first casing; wherein the first casing contains at least one of: - a chamber (B'), wherein the chamber is in fluid communication with both the exhaust gas inlet and the exhaust gas outlet and wherein the chamber (B') is lined with sound absorbing material, especially roving fiberglass; - a resonating chamber (A, C) harmonically tuned to cause destructive interference, especially a cavity resonator using Helmholtz resonance; characterized in that the sound generator (1; 1") further comprises at least one flexible membrane (14; 14, 14') coupled to the first casing in an air tight manner so as to separate the at least one electro-acoustical transducer from the exhaust gas inlet and the exhaust gas outlet. - a first casing with at least one exhaust gas inlet and at least one exhaust gas outlet different from the at least one exhaust gas inlet; and - at least one electro-acoustical transducer that is configured to produce sound in dependence on an electrical control signal; - a chamber (B'), wherein the chamber is in fluid communication with both the exhaust gas inlet and the exhaust gas outlet and wherein the chamber (B') is lined with sound absorbing material, especially roving fiberglass; - a resonating chamber (A, C) harmonically tuned to cause destructive interference, especially a cavity resonator using Helmholtz resonance;
Computer-implemented method for segmenting metal objects (8, 9) in multiple two-dimensional projection images acquired using different projection geometries, each projection image showing a region of interest, wherein a three-dimensional x-ray image is reconstructed from the two-dimensional projection images in the region of interest, the method comprising the steps of: - using a trained artificial intelligence segmentation algorithm to calculate first binary metal masks for each projection image, - reconstructing a three-dimensional intermediate data set of a reconstruction region, which is larger than the region of interest, by determining, for each voxel of the intermediate data set, a metal value by back-projection of the first binary metal masks, wherein determining the metal value comprises counting, for each voxel of the resulting intermediate data set, how many pixels, associated with a ray crossing the voxel according to the respective known projection geometry and measured in a projection image, are described as showing metal by the first binary metal mask, - determining a three-dimensional binary metal mask, in which a voxel shows metal when the metal value is larger than a threshold value and no metal in all other cases, - determining second binary metal masks for each projection image by forward projecting the three-dimensional binary metal mask using the respective projection geometries. - using a trained artificial intelligence segmentation algorithm to calculate first binary metal masks for each projection image, - reconstructing a three-dimensional intermediate data set of a reconstruction region, which is larger than the region of interest, by determining, for each voxel of the intermediate data set, a metal value by back-projection of the first binary metal masks, wherein determining the metal value comprises counting, for each voxel of the resulting intermediate data set, how many pixels, associated with a ray crossing the voxel according to the respective known projection geometry and measured in a projection image, are described as showing metal by the first binary metal mask, - determining a three-dimensional binary metal mask, in which a voxel shows metal when the metal value is larger than a threshold value and no metal in all other cases, - determining second binary metal masks for each projection image by forward projecting the three-dimensional binary metal mask using the respective projection geometries.