mhurhangee/ep-ind-claims huggingface dataset:
A compound of formula I, A is a isoxazolyl or triazolyl; B is a pyrazinyl, pyrimidinyl or pyridinyl; R 1 is methyl; R 2 is methyl; R 3 is selected from the group consisting of i) hydrogen, ii) C 3-6 -cycloalkyl, iii) halogen-C 1-6 -alkyl, and iv) C 1-6 -alkyl; R 4 is selected from the group consisting of i) hydrogen, and ii) C 1-6 -alkyl; R 5 is selected from the group consisting of i) C 1-6 -alkyl, and ii) halogen-C 1-6 -alkyl; R 6 is F; R 7 is selected from the group consisting of i) amino, ii) cyano, iii) hydrogen, iv) OH, v) halogen, vi) C 1-6 -alkyl, vii) C 1-6 -alkyl-C 3-6 -cycloalkyl, viii) halogen-C 1-6 -alkyl, ix) C 1-6 -alkoxy-C 1-6 -alkyl, x) C 2-6 -alkynyl, xi) C 2-6 -alkynyl-C 1-6 -alkyl, xii) C 2-6 -alkynyl-C 1-6 -alkoxy xiii) C 1-6 -alkoxy, and xiv) halogen-C 1-6 -alkoxy; or pharmaceutically acceptable salts thereof. A is a isoxazolyl or triazolyl; B is a pyrazinyl, pyrimidinyl or pyridinyl; R 1 is methyl; R 2 is methyl; R 3 is selected from the group consisting of i) hydrogen, ii) C 3-6 -cycloalkyl, iii) halogen-C 1-6 -alkyl, and iv) C 1-6 -alkyl; i) hydrogen, ii) C 3-6 -cycloalkyl, iii) halogen-C 1-6 -alkyl, and iv) C 1-6 -alkyl; R 4 is selected from the group consisting of i) hydrogen, and ii) C 1-6 -alkyl; i) hydrogen, and ii) C 1-6 -alkyl; R 5 is selected from the group consisting of i) C 1-6 -alkyl, and ii) halogen-C 1-6 -alkyl; i) C 1-6 -alkyl, and ii) halogen-C 1-6 -alkyl; R 6 is F; R 7 is selected from the group consisting of i) amino, ii) cyano, iii) hydrogen, iv) OH, v) halogen, vi) C 1-6 -alkyl, vii) C 1-6 -alkyl-C 3-6 -cycloalkyl, viii) halogen-C 1-6 -alkyl, ix) C 1-6 -alkoxy-C 1-6 -alkyl, x) C 2-6 -alkynyl, xi) C 2-6 -alkynyl-C 1-6 -alkyl, xii) C 2-6 -alkynyl-C 1-6 -alkoxy xiii) C 1-6 -alkoxy, and xiv) halogen-C 1-6 -alkoxy; i) amino, ii) cyano, iii) hydrogen, iv) OH, v) halogen, vi) C 1-6 -alkyl, vii) C 1-6 -alkyl-C 3-6 -cycloalkyl, viii) halogen-C 1-6 -alkyl, ix) C 1-6 -alkoxy-C 1-6 -alkyl, x) C 2-6 -alkynyl, xi) C 2-6 -alkynyl-C 1-6 -alkyl, xii) C 2-6 -alkynyl-C 1-6 -alkoxy xiii) C 1-6 -alkoxy, and xiv) halogen-C 1-6 -alkoxy;
A method of manufacturing a composite material, the method comprising: a. depositing a catalyst material over a deposition area, the catalyst material being patterned within the deposition area to form an array of catalyst regions which are spaced apart by gaps substantially free of catalyst material, wherein a proportion of the deposition area occupied by the catalyst regions is greater than a proportion of the deposition area which is substantially free of catalyst material; b. growing a first array of bundles of filaments on the catalyst regions, wherein growth of the filaments is catalysed by the catalyst material, each filament has a base attached to the catalyst region and a free tip, each filament is spaced apart from adjacent filaments in the bundle by an inter-filament gap, each bundle is spaced apart from adjacent bundles in the array by an inter-bundle gap substantially free of filaments, and each bundle has a base attached to the catalyst region and a free tip; c. drawing the free tips of the filaments together within each bundle, so that the inter-filament gaps become smaller at the tip of each bundle than at the base of each bundle where the filaments remain attached to the catalyst region; d. repeating steps a. and b. to provide a second array of bundles of filaments; e. positioning or growing at least part of the second array in the inter-bundle gaps of the first array; and f. impregnating the inter-filament gaps and inter-bundle gaps of both arrays with a matrix material. a. depositing a catalyst material over a deposition area, the catalyst material being patterned within the deposition area to form an array of catalyst regions which are spaced apart by gaps substantially free of catalyst material, wherein a proportion of the deposition area occupied by the catalyst regions is greater than a proportion of the deposition area which is substantially free of catalyst material; b. growing a first array of bundles of filaments on the catalyst regions, wherein growth of the filaments is catalysed by the catalyst material, each filament has a base attached to the catalyst region and a free tip, each filament is spaced apart from adjacent filaments in the bundle by an inter-filament gap, each bundle is spaced apart from adjacent bundles in the array by an inter-bundle gap substantially free of filaments, and each bundle has a base attached to the catalyst region and a free tip; c. drawing the free tips of the filaments together within each bundle, so that the inter-filament gaps become smaller at the tip of each bundle than at the base of each bundle where the filaments remain attached to the catalyst region; d. repeating steps a. and b. to provide a second array of bundles of filaments; e. positioning or growing at least part of the second array in the inter-bundle gaps of the first array; and f. impregnating the inter-filament gaps and inter-bundle gaps of both arrays with a matrix material.
Delivery head for fluid products, such as pigments or coloring products, inside a container containing a paint base to obtain a coloring product, said delivery head comprises a plurality of injection needles, characterised in that each needle comprises, aligned along a central common first axis, a connection element connecting to said delivery head, a tubular element and a perforation element, formed by a first portion, substantially with a rectilinear development which extends from the tubular element, and by a second portion which has a pointed end having a lateral surface symmetrical with respect to said first axis and curved in the direction of the first axis converging progressively toward a point provided on said first axis, an axial hole being made inside said needle which develops along said first axis for the passage of the fluid product toward a delivery opening made on the lateral surface of the pointed end of the perforation element, a channel being provided to connect said opening with said axial hole, said channel developing along a second axis inclined by a desired acute angle with respect to said first axis, the inclination of said second axis of the channel being comprised between about 15° and about 25°, determining an elongated shape of the delivery opening.
A light emitting device comprising: - a body of an indirect bandgap semiconductor material having a first face and at least one other face; - at least one pn-junction light emitting source in the body located towards the first face and configured to be driven via contacts on the body into a reverse biased breakdown light emitting mode; and - the other face being configured to transmit from the body light emitted by the at least one pn-junction light source. - a body of an indirect bandgap semiconductor material having a first face and at least one other face; - at least one pn-junction light emitting source in the body located towards the first face and configured to be driven via contacts on the body into a reverse biased breakdown light emitting mode; and - the other face being configured to transmit from the body light emitted by the at least one pn-junction light source.
A compound of formula I: or a pharmaceutically acceptable salt thereof, wherein, independently for each occurrence: R 1 is H, C1-C6 alkyl, C1-C6 fluoroalkyl, C3-C8 cycloalkyl, CF 3, optionally substituted heterocycloalkyl, aryl, heteroaryl, or a straight chain, branched, or cyclic (C1-C8)-R 9 wherein up to two CH 2 units may be replaced with O, CO, S, SO, SO 2, N, CF 2, or NR 8; R 2 is C1-C6 alkyl, deuterated C1-C6 alkyl, C1-C6 alkoxy, C1-C6 fluoroalkyl, CF 3, CHF 2, or a straight chain, branched, or cyclic (C1-C8)-R 9 wherein up to two CH 2 units may be replaced with O, CO, S, SO, SO 2, N, CF 2, or NR 8; R 3 is C1-C6 alkyl or halo; R 8 is H, C1-C6 alkyl, C3-C8 cycloalkyl, CF 3, or a straight chain, branched, or cyclic (C1-C8)-R 9 wherein up to two CH 2 units may be replaced with O, CO, S, SO, SO 2, N, CF 2, or NR, or 2 R 8 taken together with the atoms to which they are attached form a ring; R 9 is H, CF 3, CHF 2, CH 2 F, CO 2 R, halo, OH, optionally substituted aryl, heteroaryl, C3-C8 cycloalkyl, heterocycloalkyl, N 2, NRCOR, CON 2, CN, or SO 2 R; R is H, C1-C6 alkyl, optionally substituted aryl, heteroaryl, C3-C8 cycloalkyl, or heterocycloalkyl; ring A is an optionally substituted aryl, heteroaryl or heterocyclic; n is an integer from 0 to 4 inclusive; and o is an integer from 0 to 4 inclusive. R 1 is H, C1-C6 alkyl, C1-C6 fluoroalkyl, C3-C8 cycloalkyl, CF 3, optionally substituted heterocycloalkyl, aryl, heteroaryl, or a straight chain, branched, or cyclic (C1-C8)-R 9 wherein up to two CH 2 units may be replaced with O, CO, S, SO, SO 2, N, CF 2, or NR 8; R 2 is C1-C6 alkyl, deuterated C1-C6 alkyl, C1-C6 alkoxy, C1-C6 fluoroalkyl, CF 3, CHF 2, or a straight chain, branched, or cyclic (C1-C8)-R 9 wherein up to two CH 2 units may be replaced with O, CO, S, SO, SO 2, N, CF 2, or NR 8; R 3 is C1-C6 alkyl or halo; R 8 is H, C1-C6 alkyl, C3-C8 cycloalkyl, CF 3, or a straight chain, branched, or cyclic (C1-C8)-R 9 wherein up to two CH 2 units may be replaced with O, CO, S, SO, SO 2, N, CF 2, or NR, or 2 R 8 taken together with the atoms to which they are attached form a ring; R 9 is H, CF 3, CHF 2, CH 2 F, CO 2 R, halo, OH, optionally substituted aryl, heteroaryl, C3-C8 cycloalkyl, heterocycloalkyl, N 2, NRCOR, CON 2, CN, or SO 2 R; R is H, C1-C6 alkyl, optionally substituted aryl, heteroaryl, C3-C8 cycloalkyl, or heterocycloalkyl; ring A is an optionally substituted aryl, heteroaryl or heterocyclic; n is an integer from 0 to 4 inclusive; and o is an integer from 0 to 4 inclusive.
Modular device for transmitting electrical power in wireless mode including a flat element of the tile type and an inductor group comprising electrical board means and contact connector means, characterised in that the modular device further includes a bracket, and a bottom surface (Si) of the flat element is adapted for mounting said inductor group supported by said bracket attached to the bottom surface (Si) with screw coupling means; said bracket being provided with a recess for receiving said inductor group; said inductor group being positioned between the bottom surface (Si) and the bracket; said electrical board means being arranged and fixed on a graphite plate or sheet bearing magnet means; said magnet means being arranged on a central support of said bracket means.
Inclination adjuster for a vehicle seat comprising a rail and a slide piece, the slide piece being displaceable on the rail and the rail being provided as a curved rail, wherein the rail is configured in one piece and as a flat profile and comprises a plurality of latching means, characterized in that - the slide piece has a claw, the claw comprising a plurality of complementary latching means for engaging in the rail, - during an engagement of the claw in the rail the complementary latching means and the latching means cooperate positively and/or non-positively, - the complementary latching means have teeth and the latching means are configured as toothed portions, - at least one of the teeth of the complementary latching means is of wedge-shaped configuration and - during an engagement of the claw in the rail the complementary latching means protrude beyond the rail. - the slide piece has a claw, the claw comprising a plurality of complementary latching means for engaging in the rail, - during an engagement of the claw in the rail the complementary latching means and the latching means cooperate positively and/or non-positively, - the complementary latching means have teeth and the latching means are configured as toothed portions, - at least one of the teeth of the complementary latching means is of wedge-shaped configuration and - during an engagement of the claw in the rail the complementary latching means protrude beyond the rail.
Method for releasing a lock of a lid that closes a preparation vessel, in particular a preparation vessel of a kitchen appliance, which vessel is provided with a mixer and/or is heatable, in particular after the mixer and/or a heater has been switched off, a state value used for preparing food being measured and stored, the state value measured within a specified time period being compared with stored reference data and the lock being released after a delay period determined on the basis of the comparison result has elapsed, characterised in that the state value is measured within the mixing vessel such that the measured state value provides a mass and/or a force acting on a wall of the preparation vessel or the lid and/or a pressure and/or flow speed of the food contained in the preparation vessel.
An aqueous heat-curable binder composition comprising; a) 40-95 parts by weight of one or more reducing sugars, based on a total of 100 parts by weight of reducing sugars and amino acids; b) 5-60 parts by weight of one or more amino acids, based on a total of 100 parts by weight of reducing sugars and amino acids; and c) one or more condensed products formed by combining formaldehyde with a compound comprising -(X=C)-N 2 group, wherein X is O, N or S; and R is independently hydrogen or non-hydrogen organic group, or with a phenol-based compound, wherein, based on a total of 100 parts by weight of reducing sugars and amino acids, the amount of the condensed products is 5-50 parts by weight. a) 40-95 parts by weight of one or more reducing sugars, based on a total of 100 parts by weight of reducing sugars and amino acids; b) 5-60 parts by weight of one or more amino acids, based on a total of 100 parts by weight of reducing sugars and amino acids; and c) one or more condensed products formed by combining formaldehyde with a compound comprising -(X=C)-N 2 group, wherein X is O, N or S; and R is independently hydrogen or non-hydrogen organic group, or with a phenol-based compound,
Pneumatic vehicle tyre having a tread with at least one profile-block row (1, 2) which is delimited at at least one side by a circumferential groove and which is structured into profile blocks (6, 7) with block outer surfaces (6c, 7c) by way of transverse grooves (4, 5) opening into the circumferential groove and, in plan view, extending in an inclined manner in relation to the axial direction, wherein the profile blocks (6, 7) each have at least one acute-angled block corner region (6h, 7h) at the circumferential groove, wherein provision is made of acute-angled block corner regions (6h, 7h) at which the block corner is bevelled and at which, proceeding from the block outer surface (6c, 7c), there is formed a stepped structure (8 I, 8 II), said stepped structure being triangular overall in plan view and descending in steps in a radial direction and being formed by step surfaces, which extend at a first angle (ε) to the radial direction, and abutting surfaces, which extend at a second angle (η) to the radial direction, which is configured to be smaller than the first angle (ε), to the radial direction, that follow one another in an alternating manner and in each case extend between the circumferential groove and the transverse groove (4, 5), wherein the radially innermost step surface is triangular in plan view and has a tip (8a`) which is directed away from the adjoining abutting surface, and wherein the further step surfaces are each trapeziform in plan view, characterized in that, from the radially outermost step surface to the radially innermost step surface, the area of the step surfaces decreases in steps from step surface to step surface.
A method of making a composition, wherein said method comprises: providing a shaped support; incorporating a solution, comprising a metal component and a chelating agent, into said shaped support to provide a metal-incorporated support; drying said metal-incorporated support so as to provide a dried metal-incorporated support having a volatiles content in the range of from 1 to 20 wt % LOI; and incorporating a polar additive into said dried metal-incorporated support to thereby provide an additive impregnated composition, wherein the shaped support is dried at a drying temperature of 50 °C to 200 °C and subsequently calcined at a calcination temperature of 250 °C to 900 °C before incorporating the solution comprising the metal component and the chelating agent; and wherein the mean pore diameter of the calcined support is in the range of from 70 to 150 Å, the total pore volume of the calcined support is from 0.7 to 0.9 cc/g and less than 10% of the total pore volume of the calcined shaped particle of the support is contained in the pores having a pore diameter greater than 350 Å. providing a shaped support; incorporating a solution, comprising a metal component and a chelating agent, into said shaped support to provide a metal-incorporated support; drying said metal-incorporated support so as to provide a dried metal-incorporated support having a volatiles content in the range of from 1 to 20 wt % LOI; and incorporating a polar additive into said dried metal-incorporated support to thereby provide an additive impregnated composition, wherein the shaped support is dried at a drying temperature of 50 °C to 200 °C and subsequently calcined at a calcination temperature of 250 °C to 900 °C before incorporating the solution comprising the metal component and the chelating agent; and wherein the mean pore diameter of the calcined support is in the range of from 70 to 150 Å, the total pore volume of the calcined support is from 0.7 to 0.9 cc/g and less than 10% of the total pore volume of the calcined shaped particle of the support is contained in the pores having a pore diameter greater than 350 Å.
A surgical handheld instrument of the tongs or scissors type comprising the following parts: two lever elements hinged to each other, each of them including a grip portion on one side of a lever element hinge and a jaw portion on the other side of the lever element hinge, two leaf springs which are proximally connected to each of the two grip portions as spring portions extending each of the latter and which are coupled to each other at their proximal free ends via a hinged joint, characterized in that the hinged joint includes a hinge pin at the free end of the one leaf spring and at least one bearing eye at the free end of the other leaf spring, wherein the bearing eye includes a slit extending in the axial direction of the bearing eye for radial insertion of the hinge pin into the bearing eye. two lever elements hinged to each other, each of them including a grip portion on one side of a lever element hinge and a jaw portion on the other side of the lever element hinge, two leaf springs which are proximally connected to each of the two grip portions as spring portions extending each of the latter and which are coupled to each other at their proximal free ends via a hinged joint, characterized in that the hinged joint includes a hinge pin at the free end of the one leaf spring and at least one bearing eye at the free end of the other leaf spring, wherein the bearing eye includes a slit extending in the axial direction of the bearing eye for radial insertion of the hinge pin into the bearing eye.
A method of manufacturing an orthosis comprising: providing electronic 3D data defining a shape of an orthosis and a first region and a second region of the orthosis, the first region having a greater compressibility than the second region; and using a 3D printer to print an orthosis based on the electronic 3D data, characterised in that: the 3D printer selectively uses materials of two or more shore hardnesses to print the orthosis to provide varying hardness across the orthosis, said materials being printed together in a single 3D printing process, such that the first region is integrally formed with the second region. providing electronic 3D data defining a shape of an orthosis and a first region and a second region of the orthosis, the first region having a greater compressibility than the second region; and using a 3D printer to print an orthosis based on the electronic 3D data, characterised in that: the 3D printer selectively uses materials of two or more shore hardnesses to print the orthosis to provide varying hardness across the orthosis, said materials being printed together in a single 3D printing process, such that the first region is integrally formed with the second region. the 3D printer selectively uses materials of two or more shore hardnesses to print the orthosis to provide varying hardness across the orthosis, said materials being printed together in a single 3D printing process, such that the first region is integrally formed with the second region.
Method for controlling an aircraft in the form of a multicopter which has a plurality of redundant rotors, preferably arranged in a common rotor plane, in order, on the one hand, to generate lift and, on the other hand, by inclination of the at least one rotor plane, also to generate propulsion, wherein attitude regulation and control of the multicopter are effected by alterations to rotor speeds in dependence upon pilot control commands, the rotors being in data-transmitting connection with one another via a fail-safe network, which is implemented with multiple redundancy, and communicating their respective operating states, especially their rotor speeds, in the network; the network contains a second plurality of controllers which, autonomously and decentrally with reference to sensor data, and preferably also with reference to the rotor operating states, each determine a control signal for at least one rotor and make that control signal available in the network; the rotors are controlled by means of the control signals so that a flight characteristic of the multicopter corresponds substantially to what has been specified by the pilot control command, characterised in that the sensor data in the network are determined by a first plurality of distributed, redundant sensor units which determine control-relevant data of the multicopter relating to inclination, acceleration, yaw rate and/or position in all three spatial axes of the multicopter and make that data available in the network.
A grain bin having a grain level sensor system, the grain bin comprising a grain conveyor having an outlet for expelling grain into the grain bin, the grain level sensor system comprising: a floater adapted to sit on top of expelled grain from the grain conveyor, wherein the grain level in the grain bin is determined based on the height (h) of the floater above the outlet; characterised in that the floater is coupled with the outlet of the grain conveyor and the system comprises a linkage connecting the outlet and the floater, such that the floater is moveable relative to the outlet. a floater adapted to sit on top of expelled grain from the grain conveyor, wherein the grain level in the grain bin is determined based on the height (h) of the floater above the outlet; characterised in that the floater is coupled with the outlet of the grain conveyor and the system comprises a linkage connecting the outlet and the floater, such that the floater is moveable relative to the outlet.