Sluice arrangement for transferring articles under aseptic conditions from serially supplied packages into a process chamber surrounded by a housing of a containment positioned in an installation room, wherein: a) the process chamber is preceded by an input station; b) an individual package comprises: ba) a container having an aseptic interior and a passage that is closed by a cover; and bb) the articles stored in the interior that are to be treated in the process chamber after the cover has been opened; c) a passage leading from the input station into the process chamber is provided for transferring the articles from the packages into the process chamber, which passage is located in a partition wall extending between the input station and the process chamber as a cutout; d) a profile seal is seated in the passage, which surrounds the latter and, together with a package that is introduced and temporarily pressed into the input station, and together with a decontamination device that is temporarily pressed into place, creates seals, whereby the adjacent surfaces enclose a spatial content and the latter can be decontaminated with the adjacent surfaces by means of the decontamination device, wherein e) e) the profile seal comprises: ea) a first circumferential sealing surface, which rests against the temporarily pressed-on decontamination device with a first contact line, which delimits an emission surface on the decontamination device; and eb) a second circumferential sealing surface, which rests against the temporarily pressed-on package with a second contact line, which delimits a process surface on the cover closing the package; and f) the emission surface is at least as large as or larger than the process surface, and that the profile seal has a flank contour facing the spatial content, along which: g) the first contact line, which is intended for interaction with the decontamination device that is temporarily pressed on, lies on the first sealing surface; h) the second contact line lies on the second sealing surface and is intended for interaction with the cover which closes the temporarily pressed-on package; and i) intermediate lines (Ln) are defined between the first and second contact lines (C1, C2), wherein: j) the first contact line has the greatest span relative to a geometric center line drawn through the cross-section of the profile seal, the spans (sn) successively decrease over the intermediate lines (Ln) down to the second contact line with the smallest span. a) the process chamber is preceded by an input station; b) an individual package comprises: ba) a container having an aseptic interior and a passage that is closed by a cover; and bb) the articles stored in the interior that are to be treated in the process chamber after the cover has been opened; ba) a container having an aseptic interior and a passage that is closed by a cover; and bb) the articles stored in the interior that are to be treated in the process chamber after the cover has been opened; c) a passage leading from the input station into the process chamber is provided for transferring the articles from the packages into the process chamber, which passage is located in a partition wall extending between the input station and the process chamber as a cutout; d) a profile seal is seated in the passage, which surrounds the latter and, together with a package that is introduced and temporarily pressed into the input station, and together with a decontamination device that is temporarily pressed into place, creates seals, whereby the adjacent surfaces enclose a spatial content and the latter can be decontaminated with the adjacent surfaces by means of the decontamination device, wherein e) e) the profile seal comprises: ea) a first circumferential sealing surface, which rests against the temporarily pressed-on decontamination device with a first contact line, which delimits an emission surface on the decontamination device; and eb) a second circumferential sealing surface, which rests against the temporarily pressed-on package with a second contact line, which delimits a process surface on the cover closing the package; and ea) a first circumferential sealing surface, which rests against the temporarily pressed-on decontamination device with a first contact line, which delimits an emission surface on the decontamination device; and eb) a second circumferential sealing surface, which rests against the temporarily pressed-on package with a second contact line, which delimits a process surface on the cover closing the package; and f) the emission surface is at least as large as or larger than the process surface, and g) the first contact line, which is intended for interaction with the decontamination device that is temporarily pressed on, lies on the first sealing surface; h) the second contact line lies on the second sealing surface and is intended for interaction with the cover which closes the temporarily pressed-on package; and i) intermediate lines (Ln) are defined between the first and second contact lines (C1, C2), wherein: j) the first contact line has the greatest span relative to a geometric center line drawn through the cross-section of the profile seal, the spans (sn) successively decrease over the intermediate lines (Ln) down to the second contact line with the smallest span.