An endoscope apparatus comprising: an endoscope including normal light image pickup means having an electronic shutter and which is adapted to pick up a subject image under normal light and fluorescence image pickup means adapted to pick up a fluorescence image from a subject; and an image processing apparatus adapted to perform signal processing on image pickup signals from the normal light image pickup means and the fluorescence image pickup means to create a normal light image and a fluorescence image, wherein the image processing apparatus includes: normal light image pickup control means adapted to drive the normal light image pickup means; fluorescence image pickup control means adapted to drive the fluorescence image pickup means; normal light image signal processing means adapted to perform signal processing on an image pickup signal from the normal light image pickup means to create a normal light image; and fluorescence image signal processing means adapted to perform signal processing on an image pickup signal including a fluorescence image of the subject to create a fluorescence image, characterized in that the normal light image pickup control means and the fluorescence image pickup control means are simultaneously driven, and that it further comprises a plurality of fluorescence transmitting filters (85, 86) having mutually different filter characteristics on a front face of the fluorescence image pickup means, wherein the fluorescence image signal processing means is adapted to create a plurality of fluorescence images under light transmitted through the plurality of fluorescence transmitting filters (85, 86). an endoscope including normal light image pickup means having an electronic shutter and which is adapted to pick up a subject image under normal light and fluorescence image pickup means adapted to pick up a fluorescence image from a subject; and an image processing apparatus adapted to perform signal processing on image pickup signals from the normal light image pickup means and the fluorescence image pickup means to create a normal light image and a fluorescence image, wherein the image processing apparatus includes: normal light image pickup control means adapted to drive the normal light image pickup means; fluorescence image pickup control means adapted to drive the fluorescence image pickup means; normal light image signal processing means adapted to perform signal processing on an image pickup signal from the normal light image pickup means to create a normal light image; and fluorescence image signal processing means adapted to perform signal processing on an image pickup signal including a fluorescence image of the subject to create a fluorescence image, characterized in that the normal light image pickup control means and the fluorescence image pickup control means are simultaneously driven, and that it further comprises a plurality of fluorescence transmitting filters (85, 86) having mutually different filter characteristics on a front face of the fluorescence image pickup means, wherein the fluorescence image signal processing means is adapted to create a plurality of fluorescence images under light transmitted through the plurality of fluorescence transmitting filters (85, 86). normal light image pickup control means adapted to drive the normal light image pickup means; fluorescence image pickup control means adapted to drive the fluorescence image pickup means; normal light image signal processing means adapted to perform signal processing on an image pickup signal from the normal light image pickup means to create a normal light image; and fluorescence image signal processing means adapted to perform signal processing on an image pickup signal including a fluorescence image of the subject to create a fluorescence image, characterized in that the normal light image pickup control means and the fluorescence image pickup control means are simultaneously driven, and that it further comprises a plurality of fluorescence transmitting filters (85, 86) having mutually different filter characteristics on a front face of the fluorescence image pickup means, wherein the fluorescence image signal processing means is adapted to create a plurality of fluorescence images under light transmitted through the plurality of fluorescence transmitting filters (85, 86).