An aerosolization system, comprising: a container (201, 550, 600, 700, 800) comprising a container body, the container (201, 550, 600, 700, 800) being configured to deliver a single uniform drop of a liquid when actuated, the container comprising a nozzle having a tip with a tip seal that prevents back flow of liquid into the container; an aerosolizer comprising: a housing defining a mouthpiece (105, 732); an aerosol generator (108, 724) disposed entirely within the housing, wherein the aerosol generator comprises a vibratable membrane having a front face and a rear face, and a vibratable element used to vibrate the membrane; the housing including an opening (501, 502; 730) that is adapted to receive a dosage of the liquid from the container (201, 550, 600, 700, 800) while the container (201, 550, 600, 700, 800) is generally external to the housing so that the container (201, 550, 600, 700, 800) can be grasped by a human hand to manually actuate the container (201, 550, 600, 700, 800) while the container (201, 550, 600, 700, 800) is outside the housing, wherein the opening (501, 502; 730) provides a liquid path configured to drain the entire dosage onto the rear face of the vibratable membrane where the dosage is stored on the rear face until the vibratable element is energized to aerosolize the entire dosage stored on the rear face. a container (201, 550, 600, 700, 800) comprising a container body, the container (201, 550, 600, 700, 800) being configured to deliver a single uniform drop of a liquid when actuated, the container comprising a nozzle having a tip with a tip seal that prevents back flow of liquid into the container; an aerosolizer comprising: a housing defining a mouthpiece (105, 732); an aerosol generator (108, 724) disposed entirely within the housing, wherein the aerosol generator comprises a vibratable membrane having a front face and a rear face, and a vibratable element used to vibrate the membrane; the housing including an opening (501, 502; 730) that is adapted to receive a dosage of the liquid from the container (201, 550, 600, 700, 800) while the container (201, 550, 600, 700, 800) is generally external to the housing so that the container (201, 550, 600, 700, 800) can be grasped by a human hand to manually actuate the container (201, 550, 600, 700, 800) while the container (201, 550, 600, 700, 800) is outside the housing, wherein the opening (501, 502; 730) provides a liquid path configured to drain the entire dosage onto the rear face of the vibratable membrane where the dosage is stored on the rear face until the vibratable element is energized to aerosolize the entire dosage stored on the rear face. a housing defining a mouthpiece (105, 732); an aerosol generator (108, 724) disposed entirely within the housing, wherein the aerosol generator comprises a vibratable membrane having a front face and a rear face, and a vibratable element used to vibrate the membrane; the housing including an opening (501, 502; 730) that is adapted to receive a dosage of the liquid from the container (201, 550, 600, 700, 800) while the container (201, 550, 600, 700, 800) is generally external to the housing so that the container (201, 550, 600, 700, 800) can be grasped by a human hand to manually actuate the container (201, 550, 600, 700, 800) while the container (201, 550, 600, 700, 800) is outside the housing, wherein the opening (501, 502; 730) provides a liquid path configured to drain the entire dosage onto the rear face of the vibratable membrane where the dosage is stored on the rear face until the vibratable element is energized to aerosolize the entire dosage stored on the rear face.