A radiographic imaging system comprising: a specimen holder; an x-ray source; an x-ray detector, wherein the x-ray detector is configured to simultaneously output a first reading from a first portion of the x-ray detector and second reading from a second portion of the x-ray detector; and a controller comprising at least one processor and memory storing instructions that, when executed by the at least one processor, cause the radiographic imaging system to perform a set of operations comprising: determining a desired exposure time; defining an exposure sequence having a plurality of specimen exposure windows, wherein each specimen exposure window of the plurality of specimen exposure windows has an exposure time period, and wherein a total of the exposure time periods of the plurality of specimen exposure windows satisfies the desired exposure time; controlling the x-ray source and the x-ray detector to obtain at least one exposure reference frame; controlling the x-ray source and the x-ray detector using the exposure sequence to obtain a plurality of exposure frames from the x-ray detector; forming a plurality of corrected exposure frames by modifying the plurality of exposure frames using the at least one exposure reference frame; summing the plurality of corrected exposure frames to form an output frame; and providing the output frame as output. a specimen holder; an x-ray source; an x-ray detector, wherein the x-ray detector is configured to simultaneously output a first reading from a first portion of the x-ray detector and second reading from a second portion of the x-ray detector; and a controller comprising at least one processor and memory storing instructions that, when executed by the at least one processor, cause the radiographic imaging system to perform a set of operations comprising: determining a desired exposure time; defining an exposure sequence having a plurality of specimen exposure windows, wherein each specimen exposure window of the plurality of specimen exposure windows has an exposure time period, and wherein a total of the exposure time periods of the plurality of specimen exposure windows satisfies the desired exposure time; controlling the x-ray source and the x-ray detector to obtain at least one exposure reference frame; controlling the x-ray source and the x-ray detector using the exposure sequence to obtain a plurality of exposure frames from the x-ray detector; forming a plurality of corrected exposure frames by modifying the plurality of exposure frames using the at least one exposure reference frame; summing the plurality of corrected exposure frames to form an output frame; and providing the output frame as output. determining a desired exposure time; defining an exposure sequence having a plurality of specimen exposure windows, wherein each specimen exposure window of the plurality of specimen exposure windows has an exposure time period, and wherein a total of the exposure time periods of the plurality of specimen exposure windows satisfies the desired exposure time; controlling the x-ray source and the x-ray detector to obtain at least one exposure reference frame; controlling the x-ray source and the x-ray detector using the exposure sequence to obtain a plurality of exposure frames from the x-ray detector; forming a plurality of corrected exposure frames by modifying the plurality of exposure frames using the at least one exposure reference frame; summing the plurality of corrected exposure frames to form an output frame; and providing the output frame as output.