A method for transmitting uplink signals including a first type of control signals including ACK/NACK signals, a second type of control signals, and data signals in a mobile communication system, the method comprising: mapping reference signals on predetermined time domain units corresponding to first specific symbols of a two-dimensional resource region comprising a plurality of symbols, wherein the two-dimensional resource region comprises plural time domain units in a first dimension and plural frequency domain units in a second dimension; serially multiplexing the second type of control signals and the data signals; sequentially mapping (603, 903) the serially multiplexed signals to the two-dimensional resource region; mapping (603, 903) at least some of the first type of control signals to second specific symbols at both time domain units adjacent to the first specific symbols by overwriting a part of the multiplexed signals mapped to the second specific symbols; mapping (603, 903) at least some of the first type of control signals to third specific symbols adjacent to the second specific symbols by overwriting a part of the multiplexed signals mapped to the third specific symbols; and performing a discrete fourier transform, DFT, for the uplink signals mapped on the two-dimensional resource region and retrieved from the two-dimensional resource region in a unit of each time domain unit of the two-dimensional resource region in accordance with each index of the plurality of frequency domain units; performing an inverse fast fourier transform, IFFT, for the DFT performed uplink signals and attaching a cyclic prefix, CP, thereto; and transmitting the uplink signals attached with the CP as single-carrier frequency division multiplexing access, SC-FDMA, symbols and transmitting the reference signals. mapping reference signals on predetermined time domain units corresponding to first specific symbols of a two-dimensional resource region comprising a plurality of symbols, wherein the two-dimensional resource region comprises plural time domain units in a first dimension and plural frequency domain units in a second dimension; serially multiplexing the second type of control signals and the data signals; sequentially mapping (603, 903) the serially multiplexed signals to the two-dimensional resource region; mapping (603, 903) at least some of the first type of control signals to second specific symbols at both time domain units adjacent to the first specific symbols by overwriting a part of the multiplexed signals mapped to the second specific symbols; mapping (603, 903) at least some of the first type of control signals to third specific symbols adjacent to the second specific symbols by overwriting a part of the multiplexed signals mapped to the third specific symbols; and performing a discrete fourier transform, DFT, for the uplink signals mapped on the two-dimensional resource region and retrieved from the two-dimensional resource region in a unit of each time domain unit of the two-dimensional resource region in accordance with each index of the plurality of frequency domain units; performing an inverse fast fourier transform, IFFT, for the DFT performed uplink signals and attaching a cyclic prefix, CP, thereto; and transmitting the uplink signals attached with the CP as single-carrier frequency division multiplexing access, SC-FDMA, symbols and transmitting the reference signals.