A communication system comprising: a digital data processor configured to produce a digital data sample and one or more control bits; a serialized transmit interface (221-I, 221-Q) coupled to the digital data processor and to a first end of a signal line, wherein the serialized transmit interface is configured to combine the digital data sample and the one or more control bits into one or more data packets, and send the one or more data packets over the signal line as one or more transmitted data packets; a serialized receive interface (260-I, 260-Q) coupled a second end of the signal line, wherein the serialized receive interface is configured to receive the one or more transmitted data packets from the signal line, produce a reconstructed digital data sample from the one or more transmitted data packets, and produce the one or more control bits from the one or more transmitted data packets; a converter circuit (262, 263) configured to produce a radio frequency, RF, input signal by performing a digital-to-analog conversion of the reconstructed digital data sample to produce an analog data sample signal, and upconverting the analog data sample signal to RF; a power amplifier; a control circuit coupled to the serialized receive interface, and configured to produce a control signal from the one or more control bits provided by the serialized receive interface and send the control signal to the power amplifier such that the control signal is time-aligned with the RF input signal; wherein the power amplifier includes a sub-circuit that is controllable based on the control signal produced by the control circuit, and the power amplifier is configured to amplify the RF input signal, and to modify operation of the sub-circuit based on the control signal. a digital data processor configured to produce a digital data sample and one or more control bits; a serialized transmit interface (221-I, 221-Q) coupled to the digital data processor and to a first end of a signal line, wherein the serialized transmit interface is configured to combine the digital data sample and the one or more control bits into one or more data packets, and send the one or more data packets over the signal line as one or more transmitted data packets; combine the digital data sample and the one or more control bits into one or more data packets, and send the one or more data packets over the signal line as one or more transmitted data packets; a serialized receive interface (260-I, 260-Q) coupled a second end of the signal line, wherein the serialized receive interface is configured to receive the one or more transmitted data packets from the signal line, produce a reconstructed digital data sample from the one or more transmitted data packets, and produce the one or more control bits from the one or more transmitted data packets; receive the one or more transmitted data packets from the signal line, produce a reconstructed digital data sample from the one or more transmitted data packets, and produce the one or more control bits from the one or more transmitted data packets; a converter circuit (262, 263) configured to produce a radio frequency, RF, input signal by performing a digital-to-analog conversion of the reconstructed digital data sample to produce an analog data sample signal, and upconverting the analog data sample signal to RF; a power amplifier; a control circuit coupled to the serialized receive interface, and configured to produce a control signal from the one or more control bits provided by the serialized receive interface and send the control signal to the power amplifier such that the control signal is time-aligned with the RF input signal; wherein the power amplifier includes a sub-circuit that is controllable based on the control signal produced by the control circuit, and the power amplifier is configured to amplify the RF input signal, and to modify operation of the sub-circuit based on the control signal.