A morcellation system, comprising: a pliable retaining carrier or pouch with a specimen-receiving opening that leads from an exterior of said retaining carrier to a substantially hollow interior of said retaining carrier, said retaining carrier insertable into an operative internal cavity of a subject or patient, said retaining carrier structured to receive a targeted, excised specimen within said substantially hollow interior; a means (16a, 16b) of tightening, cinching, closing, or sealing said specimen-receiving opening positioned on a perimeter of said specimen-receiving opening; said retaining carrier having a first position and a second position, said first position being a desufflated position within said abdominal or pelvic cavity of said subject with said specimen-receiving opening being open, said second position being an insufflated position within said abdominal or pelvic cavity of said subject with said specimen-receiving opening being closed or cinched; characterized in that the morcellation system further comprises: a plurality of elongate, flexible laparoscopic tool- or trocar-receiving channels extending externally from a lining of said retaining carrier at a spaced distance away from said specimen-receiving opening and at a spaced distance away from each other, said plurality of channels positioned on said lining of said retaining carrier such that said plurality of channels line up with laparoscopic ports on a body of said subject, said plurality of channels structured to receive one or more laparoscopic tools, said plurality of channels each having a proximal end and a distal end, said distal end of said each channel terminating at said lining of said retaining carrier within said operative internal cavity of said subject, said proximal end being external to said body of said subject when said morcellation system has been inserted into said patient or subject, each said channel having a substantially hollow interior that is in communication with said substantially hollow interior of said retaining carrier. a pliable retaining carrier or pouch with a specimen-receiving opening that leads from an exterior of said retaining carrier to a substantially hollow interior of said retaining carrier, said retaining carrier insertable into an operative internal cavity of a subject or patient, said retaining carrier structured to receive a targeted, excised specimen within said substantially hollow interior; a means (16a, 16b) of tightening, cinching, closing, or sealing said specimen-receiving opening positioned on a perimeter of said specimen-receiving opening; said retaining carrier having a first position and a second position, said first position being a desufflated position within said abdominal or pelvic cavity of said subject with said specimen-receiving opening being open, said second position being an insufflated position within said abdominal or pelvic cavity of said subject with said specimen-receiving opening being closed or cinched; characterized in that the morcellation system further comprises: a plurality of elongate, flexible laparoscopic tool- or trocar-receiving channels extending externally from a lining of said retaining carrier at a spaced distance away from said specimen-receiving opening and at a spaced distance away from each other, said plurality of channels positioned on said lining of said retaining carrier such that said plurality of channels line up with laparoscopic ports on a body of said subject, said plurality of channels structured to receive one or more laparoscopic tools, said plurality of channels each having a proximal end and a distal end, said distal end of said each channel terminating at said lining of said retaining carrier within said operative internal cavity of said subject, said proximal end being external to said body of said subject when said morcellation system has been inserted into said patient or subject, each said channel having a substantially hollow interior that is in communication with said substantially hollow interior of said retaining carrier. a plurality of elongate, flexible laparoscopic tool- or trocar-receiving channels extending externally from a lining of said retaining carrier at a spaced distance away from said specimen-receiving opening and at a spaced distance away from each other, said plurality of channels positioned on said lining of said retaining carrier such that said plurality of channels line up with laparoscopic ports on a body of said subject, said plurality of channels structured to receive one or more laparoscopic tools, said plurality of channels each having a proximal end and a distal end, said distal end of said each channel terminating at said lining of said retaining carrier within said operative internal cavity of said subject, said proximal end being external to said body of said subject when said morcellation system has been inserted into said patient or subject, each said channel having a substantially hollow interior that is in communication with said substantially hollow interior of said retaining carrier.