mhurhangee/ep-ind-claims huggingface dataset:
A device (100, 200) for electroporating and delivering one or more antigens, the device comprising: a housing having a distal tip portion; a plurality of electrode arrays (106, 108) each coupled to the tip portion, wherein the electrode arrays (106, 108) project from the tip portion; a pulse generator (116, 118, 122) electrically coupled to at least one electrode of each electrode array (106, 108); a programmable microcontroller (120, 206) electrically coupled to the pulse generator (116, 118, 122), wherein each electrode is configured to deliver an electroporating pulse to cells of epidermal tissues; and wherein the pulse generator (116, 118, 122) is powered by a battery carried within the housing, wherein the battery allows the device (100, 200) to be portable, characterized in that the electrode arrays (106, 108) define spatially separate sites, each electrode array (106, 108) includes a plurality of electrodes, and the microcontroller (120, 206) is configured to adjust parameters of the electroporating pulse of each electrode array (106, 108) independently, wherein the microcontroller (120, 206) is configured to adjust a respective quantity of electroporating pulses for each electrode array (106, 108) independently, and wherein the quantity is 1 to 10. a housing having a distal tip portion; a plurality of electrode arrays (106, 108) each coupled to the tip portion, wherein the electrode arrays (106, 108) project from the tip portion; a pulse generator (116, 118, 122) electrically coupled to at least one electrode of each electrode array (106, 108); a programmable microcontroller (120, 206) electrically coupled to the pulse generator (116, 118, 122), wherein each electrode is configured to deliver an electroporating pulse to cells of epidermal tissues; and wherein the pulse generator (116, 118, 122) is powered by a battery carried within the housing, wherein the battery allows the device (100, 200) to be portable, characterized in that the electrode arrays (106, 108) define spatially separate sites, each electrode array (106, 108) includes a plurality of electrodes, and the microcontroller (120, 206) is configured to adjust parameters of the electroporating pulse of each electrode array (106, 108) independently, wherein the microcontroller (120, 206) is configured to adjust a respective quantity of electroporating pulses for each electrode array (106, 108) independently, and wherein the quantity is 1 to 10.
A method comprising the steps of: (a) continuously moving first and second strips of thermoplastic material at the same linear speed along a path that passes between an ultrasonic horn and a rotary anvil, the movement of said first and second strips being such that respective successive sections of said first and second strips pass between said horn and said anvil, wherein said first and second strips comprise respective mutually interlockable profiles; (b) continuously rotating said anvil, wherein the anvil comprises a circular cylindrical peripheral surface and a protuberance that projects radially outward from said circular cylindrical peripheral surface, at a rate of angular rotation such that a contact portion provided by the protuberance of said anvil has a tangential velocity component equal to or approximately equal to said linear speed of said first and second strips during contact therewith; and (c) activating said ultrasonic horn to transmit ultrasonic wave energy at least during a period when said contact portion of said rotating anvil is generally opposite to said horn, the total amount of ultrasonic wave energy transmitted into adjacent portions of said first and second strips being sufficient to meld said adjacent portions together, wherein said horn is not rotating during rotation of said anvil; the method further comprising the step of cushioning deflection of said horn when said contact portion of said rotating anvil is opposite to said horn. (a) continuously moving first and second strips of thermoplastic material at the same linear speed along a path that passes between an ultrasonic horn and a rotary anvil, the movement of said first and second strips being such that respective successive sections of said first and second strips pass between said horn and said anvil, wherein said first and second strips comprise respective mutually interlockable profiles; (b) continuously rotating said anvil, wherein the anvil comprises a circular cylindrical peripheral surface and a protuberance that projects radially outward from said circular cylindrical peripheral surface, at a rate of angular rotation such that a contact portion provided by the protuberance of said anvil has a tangential velocity component equal to or approximately equal to said linear speed of said first and second strips during contact therewith; and (c) activating said ultrasonic horn to transmit ultrasonic wave energy at least during a period when said contact portion of said rotating anvil is generally opposite to said horn, the total amount of ultrasonic wave energy transmitted into adjacent portions of said first and second strips being sufficient to meld said adjacent portions together,
Process for the production of magnesium containing aluminium alloys with the following steps: A. rolling to final thickness of an aluminium sheet material B. levelling of the aluminium sheet material C. electrochemical degreasing of the aluminium sheet material D. soft annealing of the aluminium sheet material, wherein step C is carried out before step D, wherein the electrochemical degreasing is done by alternating current processing of the aluminium sheet material in sulphuric acid resulting in an aluminium oxide layer on the surface of up to 30 nm, and wherein the electrochemical degreasing takes place at a temperature between 60 - 90 °C. A. rolling to final thickness of an aluminium sheet material B. levelling of the aluminium sheet material C. electrochemical degreasing of the aluminium sheet material D. soft annealing of the aluminium sheet material,
A camera comprising an at least partly transparent housing and an imaging device arranged inside the at least partly transparent housing, wherein the imaging device is configured to capture images through the at least partly transparent housing, the camera further comprising a casing at least partly enclosing the imaging device and arranged between the housing and the imaging device, the casing defining at least one cavity forming an intermediate space being in fluid communication with an inner space present between the casing and the imaging device and an outer space present between the housing and the casing, wherein the at least one cavity comprises a first cavity and a second cavity defined by a multi-walled structure of the casing comprising an outer wall, an inner wall and a partition wall.
A wireless base station (100; 101; 102) capable of communicating with an adjacent wireless base station (100; 101; 102), comprising handover controlling means for controlling handover by referencing wireless environment information of adjacent cells (30; 31; 32) notified from said adjacent wireless base station (100; 101; 102).
A toner cartridge comprising: (i) a casing including (i-i) a toner accommodation chamber accommodating toner, (i-ii) a discharge opening capable of discharging toner, and (i-iii) a communication port for fluid communication between the toner accommodation chamber and a toner discharging chamber, the discharge opening being capable of discharging toner from the toner discharging chamber to the outside of the toner cartridge; (ii) a feeding member (54, 154) movable relative to the casing and configured to feed the toner from the toner accommodation chamber through the communication port into the toner discharging chamber; (iii) a pump (58, 83) configured to discharge the toner through the discharge opening by using air, wherein at least a part of the feeding member (54, 154) is in the communication port, and wherein in a cross-sectional plane perpendicular to a toner feeding direction of the feeding member (54, 154), a minimum cross-sectional area of the communication port is Asmin, the toner discharging chamber has a cross-sectional area Bs larger than Asmin, and the toner accommodation chamber has a cross-sectional area Cs larger than Asmin. (i) a casing including (i-i) a toner accommodation chamber accommodating toner, (i-ii) a discharge opening capable of discharging toner, and (i-iii) a communication port for fluid communication between the toner accommodation chamber and a toner discharging chamber, the discharge opening being capable of discharging toner from the toner discharging chamber to the outside of the toner cartridge; (ii) a feeding member (54, 154) movable relative to the casing and configured to feed the toner from the toner accommodation chamber through the communication port into the toner discharging chamber; (iii) a pump (58, 83) configured to discharge the toner through the discharge opening by using air, wherein at least a part of the feeding member (54, 154) is in the communication port, and wherein in a cross-sectional plane perpendicular to a toner feeding direction of the feeding member (54, 154), a minimum cross-sectional area of the communication port is Asmin, the toner discharging chamber has a cross-sectional area Bs larger than Asmin, and the toner accommodation chamber has a cross-sectional area Cs larger than Asmin. a minimum cross-sectional area of the communication port is Asmin, the toner discharging chamber has a cross-sectional area Bs larger than Asmin, and the toner accommodation chamber has a cross-sectional area Cs larger than Asmin.
Apparatus for injection moulding of objects made of plastics comprising a first piece provided with an hinge pin, and a second piece provided with an annular element that are connectable in an articulated manner, the apparatus comprising: an injection mould (20, 21), comprising a first moulding member and a second moulding member defining the impressions of the annular element and of the hinge pin respectively, said first and second moulding members comprising respectively a first pin element and a second pin element, that are movable slidably and coaxially together, wherein said first and second pin element comprise respectively a first moulding end and a second moulding end for moulding said hinge pin and said annular element respectively; an extracting device which is movable linearly in an axial direction comprising an external ring nut that is movable in an axial direction, said first and second pin elements being supported in a radially movable manner by said extracting ring nut, cam drive means (46, 47) for moving selectively said first and second moulding members between an advanced moulding condition, an assembly condition and a retracted condition of disengagement of the pin and of the annular hinge element; said first and second moulding members being supported by a component that is movable from the mould, forming part of the extracting device; characterised in that it further comprises cooling means for cooling said first and second pin elements with a cooling fluid wherein said cooling means comprises a channel inside the first pin element, a tubular element inside the channel in a longitudinal direction along the axis of the channel, said channel and tubular element being coaxial to one another. an injection mould (20, 21), comprising a first moulding member and a second moulding member defining the impressions of the annular element and of the hinge pin respectively, said first and second moulding members comprising respectively a first pin element and a second pin element, that are movable slidably and coaxially together, wherein said first and second pin element comprise respectively a first moulding end and a second moulding end for moulding said hinge pin and said annular element respectively; an extracting device which is movable linearly in an axial direction comprising an external ring nut that is movable in an axial direction, said first and second pin elements being supported in a radially movable manner by said extracting ring nut, cam drive means (46, 47) for moving selectively said first and second moulding members between an advanced moulding condition, an assembly condition and a retracted condition of disengagement of the pin and of the annular hinge element; said first and second moulding members being supported by a component that is movable from the mould, forming part of the extracting device; characterised in that it further comprises cooling means for cooling said first and second pin elements with a cooling fluid
A flying vehicle comprising a flight control unit and a wireless communication device, wherein the flight control unit is configured to control flight of the flying vehicle, and wherein the wireless communication device further comprises: a wireless communication part configured to receive a wireless signal transmitted from a wireless base station; and characterized in that the wireless communication device further comprises: a cell counter configured to count a number of cells corresponding to wireless base stations identified by wireless signals received by the wireless communication part according to a predetermined cell identifying method in a predetermined time in which the flight control unit controls the flying vehicle to fly; and a communication controller configured to determine whether or not a cell count counted by the cell counter satisfies a predetermined condition, wherein the communication controller changes a communication party selecting method to select the wireless base station serving as a communication party from among a plurality of wireless base stations serving as communication party candidates when the cell count counted by the cell counter satisfies a predetermined condition. a cell counter configured to count a number of cells corresponding to wireless base stations identified by wireless signals received by the wireless communication part according to a predetermined cell identifying method in a predetermined time in which the flight control unit controls the flying vehicle to fly; and a communication controller configured to determine whether or not a cell count counted by the cell counter satisfies a predetermined condition, wherein the communication controller changes a communication party selecting method to select the wireless base station serving as a communication party from among a plurality of wireless base stations serving as communication party candidates when the cell count counted by the cell counter satisfies a predetermined condition.
A biosensor electrode comprising: a. a polymeric film substrate; and b. a conductive layer disposed adjacent the substrate; c. wherein the conductive layer consists of krypton and a conductive material, wherein the conductive material is aluminum, cobalt, copper, indium, iridium, iron, magnesium, nickel, niobium, osmium, platinum, rhenium, rhodium, selenium, silver, tantalum, tin, titanium, vanadium, zirconium, mixtures thereof, alloys of any of these elements, oxides of any of these elements, or metallic compounds of any of these elements; d. wherein the conductive layer has an average thickness of no greater than 150 nanometers; e. wherein the conductive layer has a scratch resistance of not greater than 87 microns in width, wherein scratch resistance is determined by scratching the conductive layer using an Erichsen Hardness Test Pencil model 308S under a 0.5 N load; and f. wherein krypton is present in the conductive layer in an amount of at least 1×10 14 Atoms/cm 3 at a depth of 5 nanometers as measured according to SIMS. a. a polymeric film substrate; and b. a conductive layer disposed adjacent the substrate; c. wherein the conductive layer consists of krypton and a conductive material, wherein the conductive material is aluminum, cobalt, copper, indium, iridium, iron, magnesium, nickel, niobium, osmium, platinum, rhenium, rhodium, selenium, silver, tantalum, tin, titanium, vanadium, zirconium, mixtures thereof, alloys of any of these elements, oxides of any of these elements, or metallic compounds of any of these elements; d. wherein the conductive layer has an average thickness of no greater than 150 nanometers; e. wherein the conductive layer has a scratch resistance of not greater than 87 microns in width, wherein scratch resistance is determined by scratching the conductive layer using an Erichsen Hardness Test Pencil model 308S under a 0.5 N load; and f. wherein krypton is present in the conductive layer in an amount of at least 1×10 14 Atoms/cm 3 at a depth of 5 nanometers as measured according to SIMS.
A method for determining when an agent which inhibits the production of, limits the function of, and/or destroys, regulator T cells, is to be administered to a mammalian subject with a cancer that has been exposed to a treatment which increases the number of, and/or activates, effector T cells directed against cancer cells, the method comprising analysing a sample obtained from the subject after the treatment for effector and/or regulator T cell numbers or activity, or an acute phase inflammatory marker, wherein the timing of administration of the agent will be selected such that it exerts a proportionally greater effect against the regulator T cells than the effector T cells, and wherein the agent is selected from the group consisting of anti-proliferative drugs, radiation, and an antibody which inhibits the down regulation activity of the regulator T cells.
A wireless power transmitter, comprising: a first drive circuit of a first type, the first drive circuit being configured to drive a first transmit coil at a first frequency: and a second drive circuit of a second type, the second drive circuit being configured to drive a second transmit coil at a second frequency higher than the first frequency; characterised in that it further comprises an enable circuit configured to enable the first drive circuit to drive the second drive circuit at the second frequency. a first drive circuit of a first type, the first drive circuit being configured to drive a first transmit coil at a first frequency: and a second drive circuit of a second type, the second drive circuit being configured to drive a second transmit coil at a second frequency higher than the first frequency; characterised in that it further comprises an enable circuit configured to enable the first drive circuit to drive the second drive circuit at the second frequency.
A video scalable encoding method, which comprises: - for each of reference image regions: calculating a first weight coefficient which includes a proportional coefficient (w 0) and an offset coefficient (d 0) and indicates brightness variation between an encoding target image region and the reference image region, wherein both the encoding target image region and the reference image region belong to an upper layer (Layer # 1), and correcting the reference image region with the first weight coefficient, - after processing all reference image regions, executing motion estimation to select at least one of the reference image regions (B 0), - executing motion compensation with the at least one selected reference image region (B 0), the method being characterized in that, for each of the reference image regions, calculating the first weight coefficient comprises a step that, when an immediately-lower image region (B a), which is present at spatially the same position as the encoding target image region in an immediately-lower layer (Layer # l-1), performed interframe prediction in the immediately-lower layer (Layer # l-1), identifies an immediately-lower layer reference image region (B b0) that the immediately-lower image region (B a) used as a prediction reference in weighted motion prediction, and calculates the first weight coefficient by: correcting a DC component (R(l, t-T 0, B c0)) of an image region (B c0) in the upper layer, which is present at spatially the same position as the immediately-lower layer reference image region (B b0), with a second weight coefficient (w 0 ', d 0 ') that the immediately-lower image region (B a) used in weighted motion prediction, determining the result of the correcting to be a DC component (R(l-1, t, B a)) of the immediately-lower image region (B a), and calculating the proportional coefficient (w 0) or the offset coefficient (d 0) according to the determined DC component (R(l-1, t, B a)) of the immediately-lower image region (B a) and a DC component of the reference image region. - for each of reference image regions: calculating a first weight coefficient which includes a proportional coefficient (w 0) and an offset coefficient (d 0) and indicates brightness variation between an encoding target image region and the reference image region, wherein both the encoding target image region and the reference image region belong to an upper layer (Layer # 1), and correcting the reference image region with the first weight coefficient, calculating a first weight coefficient which includes a proportional coefficient (w 0) and an offset coefficient (d 0) and indicates brightness variation between an encoding target image region and the reference image region, wherein both the encoding target image region and the reference image region belong to an upper layer (Layer # 1), and correcting the reference image region with the first weight coefficient, - after processing all reference image regions, executing motion estimation to select at least one of the reference image regions (B 0), - executing motion compensation with the at least one selected reference image region (B 0),
A transmission system, especially for a motor vehicle, having around an axis at least an input shell that is rotationally connected to a driving shaft and to a drive web in order to rotationally connect said input shell to a double wet clutch mechanism that is controlled to selectively couple said driving shaft to a first driven shaft and to a second driven shaft, said double wet clutch mechanism having at least a first clutch and a second clutch respectively of the multiple-disc type, each of said first and second clutches (E1, E2) having at least one axially movable piston (30, 90) that is controlled as to displacement by means of a control chamber (32, 92) with which is associated a compensating chamber (48, 108) delimited at least by a compensating piston (50, 110), said piston (30, 90) causing axial clamping, in an engaged position, of a multiple-disc assemblage against reaction means, said multiple-disc assemblage having at least friction discs (64, 114) rotationally connected to an external disc carrier (66, 116) and flanges (76, 126) that are rotationally connected via at least one internal disc carrier (80, 130) to one of said first and second driven shafts (A1, A2), Characterized in that the drive web, the internal disc carrier of the first clutch, the internal disc carrier of the second clutch, and said reaction means interposed axially between said internal disc carriers (80, 130) are separate parts; and said double wet clutch mechanism has connecting means arranged axially between the pistons (30, 90) of the first clutch and of the second clutch which, for direct transmission of input power, connect at least the separate parts together with zero axial clearance.