mhurhangee/ep-ind-claims huggingface dataset:
A method of generating spinal neural progenitor cells (spNPCs) comprising: providing induced pluripotent stem cells (iPSCs); differentiating iPSCs into neural ectodermal cells by culturing in neural induction media comprising LDN193189, SB431542, and CHIR99021 for about 5-7 days; and dissociating neural ectodermal cells, replating on a cell culture substrate and further culturing the replated neural ectodermal cells in differentiation media for about 5-7 days to generate spNPCs, wherein the differentiation media comprises retinoic acid and sonic hedgehog agonist. providing induced pluripotent stem cells (iPSCs); differentiating iPSCs into neural ectodermal cells by culturing in neural induction media comprising LDN193189, SB431542, and CHIR99021 for about 5-7 days; and dissociating neural ectodermal cells, replating on a cell culture substrate and further culturing the replated neural ectodermal cells in differentiation media for about 5-7 days to generate spNPCs, wherein the differentiation media comprises retinoic acid and sonic hedgehog agonist.
Circuit breaker having a plurality of interrupter units (5 to 8) which each have at least one movable switching element for opening and closing a current path of the interrupter unit (5 to 8), wherein - the current paths of all the interrupter units (5 to 8) are connected electrically in series, - and the circuit breaker has a drive to which each movable switching element is coupled by means of a kinematic chain for moving the switching element, wherein the kinematic chains are of equal length, characterized in that each kinematic chain has a switching rod (37, 38) which runs in a respectively associated insulator column (3, 4) on which at least one interrupter unit (5 to 8) is arranged, wherein the switching rods (37, 38) are at least approximately of equal length. - the current paths of all the interrupter units (5 to 8) are connected electrically in series, - and the circuit breaker has a drive to which each movable switching element is coupled by means of a kinematic chain for moving the switching element, the kinematic chains are of equal length, characterized in that each kinematic chain has a switching rod (37, 38) which runs in a respectively associated insulator column (3, 4) on which at least one interrupter unit (5 to 8) is arranged, wherein the switching rods (37, 38) are at least approximately of equal length.
A pharmaceutical composition comprising an IL-6 inhibitor which is an antibody that recognizes an IL-6 receptor as an active ingredient for use in preventing and/or treating a disease involving choroidal neovascularization.
Method for predictively influencing a vehicle speed, wherein the vehicle speed is influenced on a route with a change in parameter within a predefined speed corridor, wherein segments with a defined segment length and speed with steps are used, characterized in that a pre-calculation of a narrow speed corridor which covers an optimum speed profile is pre-calculated, and in that subsequently an optimum speed profile is calculated within this corridor, wherein firstly a calculation is carried out with rough speed steps for recording the narrow speed corridor and subsequently a calculation with fine speed steps is carried out.
A method performed by a user equipment, UE, in a wireless network, the method comprising: broadcasting group information for identifying a wireless communication group including the UE; and broadcasting a special synchronization signal identifier for identifying the UE as a synchronization reference source in the wireless communication group; characterized in that the wireless network comprises a plurality of base stations supporting a plurality of communication standards, and the method further comprises receiving timing offset information between two or more base stations of the plurality of base stations; and wherein the timing offset information is included in a System Information Block, SIB, message or a Radio Resource Control, RRC, message. broadcasting group information for identifying a wireless communication group including the UE; and broadcasting a special synchronization signal identifier for identifying the UE as a synchronization reference source in the wireless communication group; characterized in that the wireless network comprises a plurality of base stations supporting a plurality of communication standards, and the method further comprises receiving timing offset information between two or more base stations of the plurality of base stations; and wherein the timing offset information is included in a System Information Block, SIB, message or a Radio Resource Control, RRC, message.
A safety lock comprising a transponder and a shackle, the shackle being movable from an open state to a locked state, said transponder comprising an inlay including an IC and antenna coupling elements arranged to couple the IC with an antenna, the inlay arranged in or on a base member, the safety lock further comprising a housing arranged to envelope the base member, wherein the base member comprises a reduction zone, the mechanical strength of which is reduced compared to portions of the base member next to said reduction zone, the reduction zone being arranged under the IC and/or the antenna coupling elements of the inlay, the base member further connected to a first arresting means by an essentially inextensible connection, and wherein said shackle comprises a second arresting means, wherein in the locked state of the shackle, the first arresting means are arranged to intermesh with the second arresting means such that force striving the shackle from the locked state to the open state is arranged to being transmitted to the reduction zone characterized in that said force is additionally transmitted to the RFID inlay, and if the safety lock is opened by force, the base member is exposed to force exceeding the mechanical strength of the reduction zone, leading to damaging of the RFID inlay.
A surgical instrument (100, 200, 300) comprising: a shaft (110, 210, 310) having a distal end connectable with an intervertebral implant; and a handle (140, 240, 340) connected to a proximal end of the shaft (110, 210, 310), wherein the instrument (100, 200, 300) defines an internal fluid channel (144, 151-154; 244, 251, 254) through which a fluid can be passed, wherein the surgical instrument (100, 200, 300) further includes a tubular duct (182, 282) having a proximal end (186, 286) configured to connect to the instrument (100, 200, 300) to communicate with the internal fluid channel (144, 151-154; 244, 251, 254) and a distal end (184, 284) configured to connect to the distal end of the shaft (110, 210, 310) and to engage the implant to allow passage of a fluid from the internal fluid channel (144, 151-154; 244, 251, 254) to the implant to cause expansion of the implant, characterized in that the tubular duct (182, 282) includes a wire (188, 288) disposed within a tube (183, 283), wherein the wire (188, 288) is movable between a proximal position and a distal position, the wire (188, 288) being configured to cooperate with a mechanism of the implant when in the distal position. a shaft (110, 210, 310) having a distal end connectable with an intervertebral implant; and a handle (140, 240, 340) connected to a proximal end of the shaft (110, 210, 310), wherein the instrument (100, 200, 300) defines an internal fluid channel (144, 151-154; 244, 251, 254) through which a fluid can be passed, wherein the surgical instrument (100, 200, 300) further includes a tubular duct (182, 282) having a proximal end (186, 286) configured to connect to the instrument (100, 200, 300) to communicate with the internal fluid channel (144, 151-154; 244, 251, 254) and a distal end (184, 284) configured to connect to the distal end of the shaft (110, 210, 310) and to engage the implant to allow passage of a fluid from the internal fluid channel (144, 151-154; 244, 251, 254) to the implant to cause expansion of the implant, characterized in that the tubular duct (182, 282) includes a wire (188, 288) disposed within a tube (183, 283), wherein the wire (188, 288) is movable between a proximal position and a distal position, the wire (188, 288) being configured to cooperate with a mechanism of the implant when in the distal position.
An easy-mounting acoustic antenna comprising an array of elementary transducers, each elementary transducer comprising, between a counterweight and a horn, at least one ceramic, all the elementary transducers being mounted on a common printed circuit (7, 16) for electrical connection between the transducers and for positioning the transducers relative to one another, and at least one connector (26, 27) fixed to said printed circuit, the said acoustic antenna being characterized in that each of the transducers is mounted in such a way that the printed circuit is clamped between the ceramic(s) and the counterweight thereof and in that the weight of each element of each transducer is optimized so as to bring back the nodal point of vibration of the structure at the level of the printed circuit..
Device for storing piece goods, in particular rack or cupboard, with at least one bottom with an upper side, on which the piece goods are storable in a surveillance space, and with a lower side and with openings, which run from the upper side to the lower side, as well as signal transmitters with associated signal receivers, wherein at least one type (21, 22) is arranged in the openings at the lower side and a signal of the signal transmitters is detectable by the signal receivers, as well as a control electronic with a control system, which energize the signal transmitters and the signal receivers as well as processes signals of the signal receivers and identify them in order to identify an occupancy state (BZ1, BZ2) of the surveillance space with piece goods on the basis of the existence of a signal at the respective signal receiver.
Method for producing a container filled with a liquid from a preform having an inner volume, the method using an injection device comprising an outlet and connected to a source of the liquid, the method comprising the following steps: - placing the outlet in tight fluidic communication with the preform, - injecting the liquid from the source in the inner volume of the preform through the outlet, characterized in that: - closing a sealing barrier (57, 82) between the inner volume and the liquid source, the closed sealing barrier forming a fluid tight closed volume, said closed volume including at least the inner volume, said closing of the sealing barrier taking place once the closed volume is full of liquid, - placing a piston member (40, 70) in said closed volume, - driving said piston member (40, 70) when the sealing barrier is closed such that the liquid pressure in the closed volume increases, wherein during the actuation of the piston member (40, 70), the piston member (40, 70) enters at least in part inside the inner volume of the preform. - placing the outlet in tight fluidic communication with the preform, - injecting the liquid from the source in the inner volume of the preform through the outlet, - closing a sealing barrier (57, 82) between the inner volume and the liquid source, the closed sealing barrier forming a fluid tight closed volume, said closed volume including at least the inner volume, said closing of the sealing barrier taking place once the closed volume is full of liquid, - placing a piston member (40, 70) in said closed volume, - driving said piston member (40, 70) when the sealing barrier is closed such that the liquid pressure in the closed volume increases,
Device for safety lock comprising: - a rotor having a slot for receiving a key body and at least one housing capable of receiving at least one movable element, - a key having at least one guide groove along which the movable element can move, and - a stator comprising at least one locking part cooperating with said movable element in certain positions of the key, such that the guide groove extends over at least a part of the key body, in its length and in its height, such that in the absence of the key, the movable element is contained within the housing present in the rotor such that this movable element engages on the guide groove present on the key when inserting the latter into the cylinder and such that it then cooperates with the groove to be moved within the housing to a position where the junction between the movable element and the locking part corresponds to the interface between the rotor and the stator, the movable element then preventing the locking part from descending into its housing during rotation of the rotor. - a rotor having a slot for receiving a key body and at least one housing capable of receiving at least one movable element, - a key having at least one guide groove along which the movable element can move, and - a stator comprising at least one locking part cooperating with said movable element in certain positions of the key, such that the guide groove extends over at least a part of the key body, in its length and in its height, such that in the absence of the key, the movable element is contained within the housing present in the rotor such that this movable element engages on the guide groove present on the key when inserting the latter into the cylinder and such that it then cooperates with the groove to be moved within the housing to a position where the junction between the movable element and the locking part corresponds to the interface between the rotor and the stator, the movable element then preventing the locking part from descending into its housing during rotation of the rotor.
A self-propelled robot position measuring apparatus comprising a cable braking and backward tension device for providing a braking and backward pulling force to a cable comprising: a stand, a spool rotatably attached to the stand, the spool being adapted for the cable to be wound on it, a braking disk with a plurality of permanent magnets attached to it, the braking disk being rotatably attached to the stand, an actuator coupled to the braking disk and configured to rotate the braking disk in relation to the spool, wherein the braking disk is located coaxially with the spool and wherein the spool is made of paramagnetic material the tension device further comprising a controller connected to the actuator for changing a rotation speed of the actuator, and a spool position sensor installed on the stand and connected to the controller wherein the controller is configured to calculate the length of a wound out portion of the cable and adjust the rotation speed of the actuator in accordance with said length. a stand, a spool rotatably attached to the stand, the spool being adapted for the cable to be wound on it, a braking disk with a plurality of permanent magnets attached to it, the braking disk being rotatably attached to the stand, an actuator coupled to the braking disk and configured to rotate the braking disk in relation to the spool, wherein the braking disk is located coaxially with the spool and wherein the spool is made of paramagnetic material the tension device further comprising
A pharmaceutical composition for use in the treatment of aqueous or evaporative dry eye disease, a condition that is associated with or causes aqueous or evaporative dry eye disease, or symptoms associated therewith in an individual, the composition being suitable for topical application to an ocular surface, and comprising a therapeutically effective concentration of PRG4 suspended in an ophthalmically acceptable balanced salt solution.
Single-point ambidextrous breakage system for ceramic cutting machines that comprises: - a sliding carriage, - guides, - an actuating lever, - a through shaft, - a cam, - a die, located in the lower part of the breakage system below the supporting plane of a piece to be cut, - a separator in the upper part of the breakage system, which in turn comprises a ram, and - bearings, characterized in that: - the through shaft protrudes towards the exterior sides of the guides, there being a hole at each extremity of said through shaft to which the extractable actuating lever is coupled, due to which the activation of the breakage system can be carried out from either side of the guides, either from the left or from the right, regardless if the operator is left-handed or right-handed. - a sliding carriage, - guides, - an actuating lever, - a through shaft, - a cam, - a die, located in the lower part of the breakage system below the supporting plane of a piece to be cut, - a separator in the upper part of the breakage system, which in turn comprises a ram, and - bearings, - the through shaft protrudes towards the exterior sides of the guides, there being a hole at each extremity of said through shaft to which the extractable actuating lever is coupled, due to which the activation of the breakage system can be carried out from either side of the guides, either from the left or from the right, regardless if the operator is left-handed or right-handed.
Improved turbocompound system, in particular in the field of industrial vehicles, comprising a combustion engine having - a crankshaft, - a first turbocharger system, wherein a first turbine drives a fresh air compressor, - a power turbine arranged downstream of said first turbine, operatively coupled with said crankshaft through a clutch, wherein a first electric motor/generator is stably coupled with said turbocharger system (T, C), a second electric motor/generator is stably coupled with said power turbine, the first and second electric motor/generators (EM1, EM2) being electrically interconnected, and wherein control means (CTRL) are adapted to control said electric motor/generators (EM1, EM2) as motor or generator and adapted to control one in an opposite way with respect to the other, so that the electric energy produced by one is consumed by the other and vice versa. - a crankshaft, - a first turbocharger system, wherein a first turbine drives a fresh air compressor, - a power turbine arranged downstream of said first turbine, operatively coupled with said crankshaft through a clutch,
An apparatus for displaying medical image data of a body part, comprising: - an input unit; - a processing unit; and - an output unit; wherein, the input unit is configured to provide the processing unit with medical data of a body part; wherein, the processing unit is configured to determine subsets of medical image data from the medical data; wherein, the processing unit is configured to determine a plurality of measures of information content for the subsets of medical image data, wherein a measure of information content is associated with a subset of medical image data; wherein, the processing unit is configured to determine a plurality of weighting factors for the subsets of medical image data, wherein a weighting factor is associated with a subset of medical image data and the weighting factor is determined as a function of the measure of information content for that subset of medical image data; and wherein, the output unit is configured to output data representative of the subsets of medical image data as a function of the plurality of weighting factors; and wherein the information content is computed with the Shannon entropy; and wherein the processing unit is configured to determine a plurality of durations of time for the subsets of medical image data, wherein a duration of time is associated with a subset of medical image data and the duration of time is determined as a function of the weighting factor for that subset of medical image data; and wherein the output unit is configured to display the subsets of medical image data as a function of the plurality of durations of time. - an input unit; - a processing unit; and - an output unit;
A method for booting a device, the method comprising: detecting, by an internal controller that is part of a NAND flash memory, a reset signal associated with the device; retrieving, by the internal controller, a predetermined page of data from a location in the NAND flash memory into a register associated with the NAND flash memory in response to detecting the reset signal, wherein each page of data is retrieved from the NAND flash memory as a unit and the page of data includes instructions for use in booting the device; receiving, by the internal controller, a command from a processor coupled to the NAND flash memory to read data stored in the register, wherein the command includes an address identifying a location of at least one instruction within the register; retrieving the at least one instruction from the register by the internal controller for execution by the processor; characterised in that the method further comprises: determining, by the internal controller, if execution of the instructions in the register is complete and, in response, ending the methods if the execution is complete or continuing to receive additional commands from the processor if the execution is not complete. detecting, by an internal controller that is part of a NAND flash memory, a reset signal associated with the device; retrieving, by the internal controller, a predetermined page of data from a location in the NAND flash memory into a register associated with the NAND flash memory in response to detecting the reset signal, wherein each page of data is retrieved from the NAND flash memory as a unit and the page of data includes instructions for use in booting the device; receiving, by the internal controller, a command from a processor coupled to the NAND flash memory to read data stored in the register, wherein the command includes an address identifying a location of at least one instruction within the register; retrieving the at least one instruction from the register by the internal controller for execution by the processor; characterised in that the method further comprises: determining, by the internal controller, if execution of the instructions in the register is complete and, in response, ending the methods if the execution is complete or continuing to receive additional commands from the processor if the execution is not complete.
A dimmable LED converter, which is designed to provide at least one LED series connected to the LED converter with a current (I effA, I effB) based on a predetermined dimming value of an external control circuit, wherein in order to set the predetermined dimming value at least the temporal mean value of the amplitude of the current (I effA, I effB) through the at least one LED series as well as the duty ratio (t on /t on -t off) of current pulses can be set by means of a micro-controller, during the duty cycle (t on) of which the current (I effA, I effB) flows, wherein in at least one section of the overall dimming range in the direction towards lower dimming values the duty ratio (t on /t on -t off) of the current pulses can be reduced at constant current amplitude (I max), until the duty ratio (t on /t on -t off) reaches a predetermined lower limit value, at which in the case of a further reduction of the dimming value the duty ratio (t on /t on -t off) can be abruptly increased by a predetermined value and at the same time the current amplitude I max can be abruptly lowered to a reduced value, wherein for the further reduction of the dimming value the duty ratio (t on /t on -t off) can be reduced again at a constantly reduced current amplitude (I max), characterized in that the LED converter determines a corrective value for the duty ratio by means of the micro-controller or a memory of the LED converter, in order to compensate for a change of the emitted light of the LED series, so that in the event of a jump in the current amplitude the color coordinate of the light of the LED series remains unchanged.