A compound of formula I or II for use in the prevention and/or treatment of a disease characterized by accumulation of homogentisic acid or of succinyl acetoacetate and succinylacetone: wherein --- represents the presence or absence of a bond; - R and R 1 are identical or different and independent of each other, in ortho, meta or para position, and represent -H; -OH; -NH 2; -NO 2; -SO 2 CH 3; a halogen atom; an alkyl group; a haloalkyl group; an alkoxy group -O-alkyl; a cycloalkyl group; a phenyl group or an aryl group; - R 2, R 3, R 3a, R 4 and R 5 are identical or different and independent of each other, and represent -H; -OH; -NH 2; -NO 2; -SO 2 CH 3; a halogen atom; an alkyl group; a carbonyl group; a cycloalkyl group; an alkoxy group; a phenyl group; an aryl group, or a heteroaryl group; an amide group -C(=O)-NH-R 6 or an ester group -C(=O)-O-R 6; further, R 5 may be oxo when the bond between R 5 and the carbon to which R 5 is attached is a double bond, further, keeping the above defined substituents for R and R 1, the groups R 2 and R 3 or R 3a, R 3 or R 3a and R 4, R 4 and R 5 may be fused to form, together with the carbon atoms adjacent to the cyclohexanone group on which they are located, a cycle with 5, 6 or 7 atoms condensed to the same cyclohexanone; - R 6 represents an alkyl group, a cycloalkyl group, a phenyl group, an aryl group or a heteroaryl group; - R 7 represents: -H; -OH; -NH 2; -NO 2; -SO 2 CH 3; a halogen atom; an alkyl group; an alkoxy group; a cycloalkyl group; a phenyl group or an aryl group, wherein the compound of formula I in which R is ortho-NO 2, R 1 is para-CF 3, R 2 = R 3 = R 3a = R 4 and is H and R 5 is oxo when the bond between R 5 and the carbon to which R 5 is attached is a double bond (known as Nitisinone) is not included. --- represents the presence or absence of a bond; - R and R 1 are identical or different and independent of each other, in ortho, meta or para position, and represent -H; -OH; -NH 2; -NO 2; -SO 2 CH 3; a halogen atom; an alkyl group; - R and R 1 are identical or different and independent of each other, in ortho, meta or para position, and represent -H; -OH; -NH 2; -NO 2; -SO 2 CH 3; a halogen atom; an alkyl group; a haloalkyl group; an alkoxy group -O-alkyl; a cycloalkyl group; a phenyl group or an aryl group; - R 2, R 3, R 3a, R 4 and R 5 are identical or different and independent of each other, and represent -H; -OH; -NH 2; -NO 2; -SO 2 CH 3; a halogen atom; an alkyl group; a carbonyl group; a cycloalkyl group; an alkoxy group; a phenyl group; an aryl group, or a heteroaryl group; an amide group -C(=O)-NH-R 6 or an ester group -C(=O)-O-R 6; - R 2, R 3, R 3a, R 4 and R 5 are identical or different and independent of each other, and represent -H; -OH; -NH 2; -NO 2; -SO 2 CH 3; a halogen atom; an alkyl group; a carbonyl group; a cycloalkyl group; an alkoxy group; a phenyl group; an aryl group, or a heteroaryl group; an amide group -C(=O)-NH-R 6 or an ester group -C(=O)-O-R 6; further, R 5 may be oxo when the bond between R 5 and the carbon to which R 5 is attached is a double bond, further, keeping the above defined substituents for R and R 1, the groups R 2 and R 3 or R 3a, R 3 or R 3a and R 4, R 4 and R 5 may be fused to form, together with the carbon atoms adjacent to the cyclohexanone group on which they are located, a cycle with 5, 6 or 7 atoms condensed to the same cyclohexanone; - R 6 represents an alkyl group, a cycloalkyl group, a phenyl group, an aryl group or a heteroaryl group; - R 7 represents: -H; -OH; -NH 2; -NO 2; -SO 2 CH 3; a halogen atom; an alkyl group; an alkoxy group; a cycloalkyl group; a phenyl group or an aryl group, - R 6 represents an alkyl group, a cycloalkyl group, a phenyl group, an aryl group or a heteroaryl group; - R 7 represents: -H; -OH; -NH 2; -NO 2; -SO 2 CH 3; a halogen atom; an alkyl group; an alkoxy group; a cycloalkyl group; a phenyl group or an aryl group, wherein the compound of formula I in which R is ortho-NO 2, R 1 is para-CF 3, R 2 = R 3 = R 3a = R 4 and is H and R 5 is oxo when the bond between R 5 and the carbon to which R 5 is attached is a double bond (known as Nitisinone) is not included.