mhurhangee/ep-ind-claims huggingface dataset:
A cochlear implant hearing aid system, comprising an external part including a sound pickup unit configured to pick up sound from the environment and a sound processing unit configured to process said sound, and an external near-infrared transmitter, an implant part including an implant processing unit and a plurality of cochlea stimulation electrodes for stimulation of a cochlea of a user, a near-infrared transmitter configured to transmit a near-infrared wave, wherein said near-infrared transmitter is an internal near-infrared transmitter provided on said implant part and configured to transmit said near-infrared wave towards a cortex of said user, a near-infrared receiver configured to receive said near-infrared wave, wherein said near-infrared transmitter and said near-infrared receiver are arranged on a back of said implant part, and the back of said implant part is directed towards a skull of said user, and characterized in that said near-infrared receiver is an internal near-infrared receiver provided on said implant part and configured to receive both said near-infrared wave scattered signals from within said cortex of said user and to receive a directly transmitted near-infrared wave signal from the external near-infrared transmitter. an external part including a sound pickup unit configured to pick up sound from the environment and a sound processing unit configured to process said sound, and an external near-infrared transmitter, an implant part including an implant processing unit and a plurality of cochlea stimulation electrodes for stimulation of a cochlea of a user, a near-infrared transmitter configured to transmit a near-infrared wave, wherein said near-infrared transmitter is an internal near-infrared transmitter provided on said implant part and configured to transmit said near-infrared wave towards a cortex of said user, a near-infrared receiver configured to receive said near-infrared wave, wherein said near-infrared transmitter and said near-infrared receiver are arranged on a back of said implant part, and the back of said implant part is directed towards a skull of said user, and characterized in that said near-infrared receiver is an internal near-infrared receiver provided on said implant part and configured to receive both said near-infrared wave scattered signals from within said cortex of said user and to receive a directly transmitted near-infrared wave signal from the external near-infrared transmitter.
An imaging apparatus configured to perform a shooting operation with an illumination device, comprising: light metering means configured to obtain the luminance of the entire image-capturing screen; acquisition means configured to acquire information relating to subject distances, from the camera to a subject, which is detected for each of a plurality of areas imaged for shooting; and light emission control means configured to cause the illumination device to emit light in a shooting operation if a luminance value based on the luminance of the entire image-capturing screen obtained by the light metering means is less than a threshold, characterized by: the light emission control means being configured to reduce the threshold as a difference in subject distance among the plurality of areas based on the information acquired by the acquisition means increases. light metering means configured to obtain the luminance of the entire image-capturing screen; acquisition means configured to acquire information relating to subject distances, from the camera to a subject, which is detected for each of a plurality of areas imaged for shooting; and light emission control means configured to cause the illumination device to emit light in a shooting operation if a luminance value based on the luminance of the entire image-capturing screen obtained by the light metering means is less than a threshold, the light emission control means being configured to reduce the threshold as a difference in subject distance among the plurality of areas based on the information acquired by the acquisition means increases.
Polypeptide consisting of sequence SEQ ID NO: 1, or a variant thereof consisting of a sequence at least 85% identical to SEQ ID NO: 1, for use in the prevention and/or treatment of a bone disorder.
A determination apparatus comprising: a memory; and a processor coupled to the memory and configured to execute control processing that includes: acquiring a pulse waveform (110, W, W1 to Wm, Wj) indicating a temporal change of a measured pulse wave; calculating a first value indicating a matching degree between the acquired pulse waveform (110, W, W1 to Wm, Wj) and a model expressed as a function, the function indicating a relationship between a beat-to-beat interval corresponding to the pulse wave interval and a blood flow volume that is proportional to the pulse wave amplitude, the function describing a model temporal course of the pulse wave amplitude during a single pulse wave interval and showing a monotonic increase during this interval, the monotonic increase starting with a section in which there is no blood flow and that corresponds to the cardiac refractory period; determining whether or not the pulse waveform (110, W, W1 to Wm, Wj) contains noise based on the calculated first value; and outputting the obtained determination result (1400-1, 1400-2, 1400-3). a memory; and a processor coupled to the memory and configured to execute control processing that includes: acquiring a pulse waveform (110, W, W1 to Wm, Wj) indicating a temporal change of a measured pulse wave; calculating a first value indicating a matching degree between the acquired pulse waveform (110, W, W1 to Wm, Wj) and a model expressed as a function, the function indicating a relationship between a beat-to-beat interval corresponding to the pulse wave interval and a blood flow volume that is proportional to the pulse wave amplitude, the function describing a model temporal course of the pulse wave amplitude during a single pulse wave interval and showing a monotonic increase during this interval, the monotonic increase starting with a section in which there is no blood flow and that corresponds to the cardiac refractory period; determining whether or not the pulse waveform (110, W, W1 to Wm, Wj) contains noise based on the calculated first value; and outputting the obtained determination result (1400-1, 1400-2, 1400-3). acquiring a pulse waveform (110, W, W1 to Wm, Wj) indicating a temporal change of a measured pulse wave; calculating a first value indicating a matching degree between the acquired pulse waveform (110, W, W1 to Wm, Wj) and a model expressed as a function, the function indicating a relationship between a beat-to-beat interval corresponding to the pulse wave interval and a blood flow volume that is proportional to the pulse wave amplitude, the function describing a model temporal course of the pulse wave amplitude during a single pulse wave interval and showing a monotonic increase during this interval, the monotonic increase starting with a section in which there is no blood flow and that corresponds to the cardiac refractory period; determining whether or not the pulse waveform (110, W, W1 to Wm, Wj) contains noise based on the calculated first value; and outputting the obtained determination result (1400-1, 1400-2, 1400-3).
A method comprising: storing, at an inline network appliance, a session identifier that uniquely identifies a network communication session between a first device and the inline network appliance; receiving, at the inline network appliance, a first communication from the first device in the network communication session, wherein the data received from the first device is encrypted using a first encryption key; receiving, at the inline network appliance, from a proxy tool, a second communication that includes a header specifying the session identifier and that includes data generated by the proxy tool by modifying data from the first communication; associating, by the inline network appliance, the first communication with the second communication by using the session identifier; and transmitting an encrypted representation of the data generated by the proxy tool from the inline network appliance to a second device based on the association between the first communication and the second communication, wherein transmitting the encrypted representation of the data to the second device comprises encrypting the data generated by the proxy tool using a second encryption key. storing, at an inline network appliance, a session identifier that uniquely identifies a network communication session between a first device and the inline network appliance; receiving, at the inline network appliance, a first communication from the first device in the network communication session, wherein the data received from the first device is encrypted using a first encryption key; receiving, at the inline network appliance, from a proxy tool, a second communication that includes a header specifying the session identifier and that includes data generated by the proxy tool by modifying data from the first communication; associating, by the inline network appliance, the first communication with the second communication by using the session identifier; and transmitting an encrypted representation of the data generated by the proxy tool from the inline network appliance to a second device based on the association between the first communication and the second communication, wherein transmitting the encrypted representation of the data to the second device comprises encrypting the data generated by the proxy tool using a second encryption key.
A method to obtain the spatial location and sequence information of a target sequence in a sample comprising at least one m-RNA strand comprising the steps a. providing a surface with a plurality of spacer units capable of binding at least one m-RNA strand and with at least one fiducial marker b. providing a sample comprising at least one m-RNA strand to the surface wherein at least one m-RNA strand of the sample binds to at least one spacer unit creating at least one single stranded oligomer c. taking a first image of the surface to obtain the spatial information of the sample relative to the fiducial marker d. removing sample form surface e. hybridizing at least one oligonucleotide comprising 50 - 1000 nucleic acids with its 5' and 3' ends to complementary parts of the single stranded oligomer thereby forming a padlock-shaped structure that is ligated to create a single strand circular template f. multiplying the single strand circular template by a polymerase capable of rolling circle amplification into a plurality of DNA concatemers thereby forming rolonies g. obtaining the sequence information of the rolonies h. linking the spatial information of the sample with the sequence information of the rolonies. a. providing a surface with a plurality of spacer units capable of binding at least one m-RNA strand and with at least one fiducial marker b. providing a sample comprising at least one m-RNA strand to the surface wherein at least one m-RNA strand of the sample binds to at least one spacer unit creating at least one single stranded oligomer c. taking a first image of the surface to obtain the spatial information of the sample relative to the fiducial marker d. removing sample form surface e. hybridizing at least one oligonucleotide comprising 50 - 1000 nucleic acids with its 5' and 3' ends to complementary parts of the single stranded oligomer thereby forming a padlock-shaped structure that is ligated to create a single strand circular template f. multiplying the single strand circular template by a polymerase capable of rolling circle amplification into a plurality of DNA concatemers thereby forming rolonies g. obtaining the sequence information of the rolonies h. linking the spatial information of the sample with the sequence information of the rolonies.
A wound dressing comprising an absorbable polyelectrolyte material and ionic crystals, wherein a weight percent of ionic crystals in the absorbable polyelectrolyte material is at least about 5% w/w of an overall weight.
A implantable medical device comprising a luminal surface and a coating, wherein the coating comprises one or more layers of a matrix, one or more pharmaceutical substances that inhibits smooth muscle cell migration and/or proliferation, and a ligand attached to said matrix and operably configured to capture circulating progenitor cells on the luminal surface of said device after implantation of said medical device into a patient, characterized in that said one or more layers of said matrix are one or more layers of a non-polymer matrix, in that the non-polymer matrix is formed of a porous material comprising nano-particles, and in that the one or more pharmaceutical substances is trapped within and/or between said particles.
Biomaterial having a multi-dimensional structure comprising osteogenic differentiated adipose-derived stem cells (ASCs), a ceramic material and an extracellular matrix, wherein the biomaterial secretes osteoprotegerin and comprises insulin-like growth factor and stromal cell-derived factor 1-alpha (SDF-1α), wherein the ceramic material is in form of particles, wherein the multi-dimension of the biomaterial is due to the synthesis of extracellular matrix by adipose tissue-derived stem cells and wherein the ASCs and the ceramic particles within the biomaterial of the invention are embedded in the extracellular matrix wherein the ceramic material is in form of particles, wherein the multi-dimension of the biomaterial is due to the synthesis of extracellular matrix by adipose tissue-derived stem cells and wherein the ASCs and the ceramic particles within the biomaterial of the invention are embedded in the extracellular matrix
A bicycle comprising a frame, at least one component (18, 20, 24, 28) pressurized by means of a gaseous pressure medium, and a pressurization system which is pneumatically connected to the at least one component (18, 20, 24, 28), the pressurization system having a pressure source and a power supply unit, which is connected to the pressure source, and comprising a controller, characterized in that the controller allows defining at least one target pressure value of the at least one component (18, 20, 24, 28), the controller controls the pressurization of the at least one component (18, 20, 24, 28) by the pressure medium based on the at least one target pressure value, the controller has at least one operating unit (64, 264) and a regulating unit (70, 270), and at least one valve is provided which is connected to the controller, is controlled by the regulating unit (70, 270) and is assigned to the component (18, 20, 24, 28) and leads air into the component (18, 20, 24, 28) or out of the component (18, 20, 24, 28) as a function of a switching state.
An orthopaedic surgical instrument assembly comprising: a base trial adapted to be positioned on a proximal end of a patient's resected tibia, the base trial including a plate having: an opening defined therein, and a pair of fixation pin holes defined in an anterior aspect, and a guide tower including: a tower base adapted to be positioned on the base trial, the tower base having a passageway defined therein that is configured to be substantially aligned with the opening of the plate when the tower base is positioned on the base trial, and a pair of fixation pins, each of which is sized to be received in and extend outwardly from each of the fixation pin holes of the base trial when the tower base is positioned on the base trial, characterised in that the pair of fixation pins are provided in and extend downwardly from an anterior aspect of the tower base so that, when the tower base is positioned over the base trial, the fixation pins extending downwardly from the anterior aspect of the tower base can be aligned with the fixation pin holes in the plate of the base trial. a base trial adapted to be positioned on a proximal end of a patient's resected tibia, the base trial including a plate having: an opening defined therein, and a pair of fixation pin holes defined in an anterior aspect, and an opening defined therein, and a pair of fixation pin holes defined in an anterior aspect, and a guide tower including: a tower base adapted to be positioned on the base trial, the tower base having a passageway defined therein that is configured to be substantially aligned with the opening of the plate when the tower base is positioned on the base trial, and a pair of fixation pins, each of which is sized to be received in and extend outwardly from each of the fixation pin holes of the base trial when the tower base is positioned on the base trial, a tower base adapted to be positioned on the base trial, the tower base having a passageway defined therein that is configured to be substantially aligned with the opening of the plate when the tower base is positioned on the base trial, and a pair of fixation pins, each of which is sized to be received in and extend outwardly from each of the fixation pin holes of the base trial when the tower base is positioned on the base trial, characterised in that the pair of fixation pins are provided in and extend downwardly from an anterior aspect of the tower base so that, when the tower base is positioned over the base trial, the fixation pins extending downwardly from the anterior aspect of the tower base can be aligned with the fixation pin holes in the plate of the base trial.
A locking pin (22, 110) for mounting an airbag module in a height-movable manner in the direction of its longitudinal center axis (94, 138) on a skeleton of a vehicle steering wheel and at least in portions inside a foam wrapping of the skeleton, wherein the locking pin (22, 110) includes at least one stop (70, 72, 128, 136) for the airbag module which is formed integrally with the locking pin (22, 110), characterized in that the at least one stop (70, 72, 128, 136) includes a land (74, 76, 122, 130) radially pointing away from the locking pin (22, 110) which land merges into an at least approximately U-shaped bracket (78, 80, 124, 132) having two legs (82, 84; 90, 92) spaced apart in the direction of the longitudinal center axis (94, 138).
A method of replacing a module (50, 52, 54) in a modular gas turbine engine carried out with the engine mounted on a wing of an aircraft, wherein the gas turbine engine comprises: a first fan module comprising a fan having plurality of fan blades; a first engine core module including an engine core and a gearbox arranged to provide drive to the fan; and a first fan case module comprising a fan case arranged to enclose the fan blades, the method including the steps of: disassembling the gas turbine engine, replacing one of the first fan module, the first engine core module or the first fan case module with a replacement fan module, a replacement engine core module or a replacement fan case module, the replacement module (50', 52', 54'), having the same configuration as the first module (50, 52, 54); and reassembling the gas turbine engine using the replacement module (50', 52', 54'); characterised in that each module is arranged to enable the thrust contribution of each module to be determined independently and is w subjected to a separate passing off process to determine a power setting parameter for the respective module; and totalling the contributions from each module to determine a total thrust generated by the engine without having to pass of the whole engine as a completed unit. disassembling the gas turbine engine, replacing one of the first fan module, the first engine core module or the first fan case module with a replacement fan module, a replacement engine core module or a replacement fan case module, the replacement module (50', 52', 54'), having the same configuration as the first module (50, 52, 54); and reassembling the gas turbine engine using the replacement module (50', 52', 54'); characterised in that each module is arranged to enable the thrust contribution of each module to be determined independently and is w subjected to a separate passing off process to determine a power setting parameter for the respective module; and totalling the contributions from each module to determine a total thrust generated by the engine without having to pass of the whole engine as a completed unit.
A method for increasing the hydrophilicity of only an internal region of a polymeric material having a UV absorber, said method comprising: generating a pulsed laser radiation output from a laser source having a wavelength selected to interact with said UV absorber within said internal region of said PM; distributing said pulsed laser radiation output across an input area of a microscope objective; accepting said distributed pulsed radiation into a numerical aperture within said microscope objective to produce a focused laser radiation output; transmitting said focused laser radiation output to said internal region within said PM to increase the hydrophilicity of said internal region of said PM; exposing said internal region to water; and allowing said PM to absorb water thus reducing the refractive index of said internal region of said PM. generating a pulsed laser radiation output from a laser source having a wavelength selected to interact with said UV absorber within said internal region of said PM; distributing said pulsed laser radiation output across an input area of a microscope objective; accepting said distributed pulsed radiation into a numerical aperture within said microscope objective to produce a focused laser radiation output; transmitting said focused laser radiation output to said internal region within said PM to increase the hydrophilicity of said internal region of said PM; exposing said internal region to water; and allowing said PM to absorb water thus reducing the refractive index of said internal region of said PM.
An apparatus for facilitating an insertion of a wire surrounded by shielding into an electrical component so as to prevent a dislocation of the shielding during insertion, the apparatus comprising: a wire receiver defining a cavity having a first end and a second end, wherein at least a portion of the first end and a portion of the second end defines a wire axis, and wherein the cavity is configured to receive the wire along the wire axis; and one or more conduits disposed between the first end and the second end and configured to direct air flow radially inwardly toward the wire axis to force the shielding against the wire received within the cavity, the one or more conduits comprising an air inlet configured to receive pressurized gas from a gas source and an air outlet fluidically connected to an air channel, wherein the apparatus further comprises a plurality of said air channels (234A-D), each air channel fluidically coupled to said air inlet and said air outlet, each of the air channels (234A-D) comprising a channel inlet fluidically coupled to said air inlet and a channel outlet fluidically coupled to said air outlet, and wherein the channel outlets of the plurality of air channels are substantially evenly disposed around an inner perimeter of the cavity. a wire receiver defining a cavity having a first end and a second end, wherein at least a portion of the first end and a portion of the second end defines a wire axis, and wherein the cavity is configured to receive the wire along the wire axis; and one or more conduits disposed between the first end and the second end and configured to direct air flow radially inwardly toward the wire axis to force the shielding against the wire received within the cavity, the one or more conduits comprising an air inlet configured to receive pressurized gas from a gas source and an air outlet fluidically connected to an air channel, wherein the apparatus further comprises a plurality of said air channels (234A-D), each air channel fluidically coupled to said air inlet and said air outlet, each of the air channels (234A-D) comprising a channel inlet fluidically coupled to said air inlet and a channel outlet fluidically coupled to said air outlet, and wherein the channel outlets of the plurality of air channels are substantially evenly disposed around an inner perimeter of the cavity.