mhurhangee/ep-ind-claims huggingface dataset:
A locking strip fitting embodied as corner deflector for a corner area of a window, a door or the like, comprising a holding part, which is operatively connected to two locking strips, which run at an angle to one another, which is defined by the corner area, wherein the holding part can be rotatably supported on a base part, which is to be arranged in a stationary manner, by means of a rotary bearing, characterized in that two support elements (30, 31) are pivotally hinged to the holding part by means of pivot bearings (28, 29), wherein one of the locking strips (51, 52) is fastened to each support element (30, 31) by means of a connection.
A conjugate comprising a protein, and one or several multivalent cell-penetrating peptide(s) (multivalent CPP(s)) each multivalent CPP comprising at least two cell-penetrating peptides (CPPs), wherein the multivalent CPP(s) is/are covalently attached to the protein, wherein each of the multivalent CPP(s) is a dendrimer of cell-penetrating peptides (cell-penetrating peptide dendrimer, dCPP) comprising a dendrimer core and at least two cell-penetrating peptides (CPPs), which are coupled to the dendrimer core, said dendrimer core being a peptidyl dendrimer core comprising lysines as branching points and cysteine(s) as the anchoring group(s), and comprises or consists of or wherein K is Lys, A is Ala and C is Cys, wherein the cell-penetrating peptide(s) comprise the amino acid sequence of penetratin (SEQ ID NO. 1), TAT (human immunodeficiency virus-derived trans-activator of transcription, SEQ ID NO. 2), PreS2-TLM (hepatitis B virus-preS2-domain-derived translocation motif, SEQ ID NO. 3), R9 (SEQ ID NO. 4), MTS (membrane translocation signal, SEQ ID NO. 5), SynBl (synthetic porcine protegrin 1-derived CPP, SEQ ID NO. 6), pVEC (vascular endothelial cadherin-derived CPP, SEQ ID NO. 7), NLS (nuclear localization signal, SEQ ID NO. 8), or combinations thereof. TAT (human immunodeficiency virus-derived trans-activator of transcription, SEQ ID NO. 2), PreS2-TLM (hepatitis B virus-preS2-domain-derived translocation motif, SEQ ID NO. 3), R9 (SEQ ID NO. 4), MTS (membrane translocation signal, SEQ ID NO. 5), SynBl (synthetic porcine protegrin 1-derived CPP, SEQ ID NO. 6), pVEC (vascular endothelial cadherin-derived CPP, SEQ ID NO. 7), NLS (nuclear localization signal, SEQ ID NO. 8),
A comb polymer consisting essentially of the following structure: comprising a backbone formed of alternating branch-point moieties B and hydrophilic, water-soluble polymer blocks A; and having hydrophobic side chains C and optional ligands Z attached to the branch-point moieties, wherein: the water-soluble polymer block A is selected from the group consisting of poly(ethylene glycol), poly(propylene glycol), poly(ethyleneimine), poly(vinyl alcohol), and poly(vinylpyrrolidone), and copolymers thereof; the branch-point moiety B is a conjugate of dithiothreitol, dithioerythritol, or 2,3-diaminobutane-1,4-dithiol with two molecules of maleic acid; each hydrophobic side chain C has a logP value greater than 1.4, and is independently selected from the group consisting of C 6 -C 30 linear or branched hydrocarbons optionally substituted with one or more hydrophilic substituents; C 6 -C 30 cyclic or polycyclic hydrocarbons optionally substituted with one or more hydrophilic substituents; and hydrophobic amino acids, peptides and polymers; each ligand Z is independently a ligand having specific binding affinity for the surface of a virus; s is a bond or a spacer moiety; the value of n ranges from 3 to about 100; the average value of p ranges from greater than one to four; and the average value of r ranges from 1 to 4; with the proviso that the comb polymer is not: where -NH-Z is 6'-N-linked 5-acetamido-7-(6'-aminohexyl)-carbamyloxy-4-guanidino-2,3,4,5-tetradeoxy-D-glycero-D-galacto-non-2-enopyranosonic acid (zanamivir); where -NH-Z is N-linked β- O -methyl neuraminic acid; or where Z is neuraminyl (NANA). the water-soluble polymer block A is selected from the group consisting of poly(ethylene glycol), poly(propylene glycol), poly(ethyleneimine), poly(vinyl alcohol), and poly(vinylpyrrolidone), and copolymers thereof; the branch-point moiety B is a conjugate of dithiothreitol, dithioerythritol, or 2,3-diaminobutane-1,4-dithiol with two molecules of maleic acid; each hydrophobic side chain C has a logP value greater than 1.4, and is independently selected from the group consisting of C 6 -C 30 linear or branched hydrocarbons optionally substituted with one or more hydrophilic substituents; C 6 -C 30 cyclic or polycyclic hydrocarbons optionally substituted with one or more hydrophilic substituents; and hydrophobic amino acids, peptides and polymers; each ligand Z is independently a ligand having specific binding affinity for the surface of a virus; s is a bond or a spacer moiety; the value of n ranges from 3 to about 100; the average value of p ranges from greater than one to four; and the average value of r ranges from 1 to 4;
Shearing apparatus to selectively shear at least a support element, preferably a continuous strip, even more preferably provided with cells, mobile in a direction of feed, said shearing apparatus comprising at least a first shearing device that is provided with a shearing member and selectively drivable between an idle position, in which said shearing member does not interfere with said support element, and an operating shearing position, in which said shearing member at least partly interferes with said support element, by driving a drive member, characterized in that said first shearing device is mounted on a slider mobile along a travel in a direction perpendicular to said direction of feed, by means of said drive member, between a position distanced from said support element, which corresponds to said idle position of said shearing member, and a position of interference with said support element, which corresponds to said operating shearing position of said shearing member, wherein said first shearing device also comprises an actuation device configured to actuate said shearing member and selectively take it into a first operating condition, in which said shearing member totally interferes with said support element, shearing it completely and thus achieving at least a unitary section of the latter which detaches from a lateral off-cut thereof, or into a second operating condition, in which said shearing member only partly interferes with said support element, so the corresponding unitary section, not completed, remains attached to the lateral off-cut of the latter, wherein in said two operating conditions of the shearing member, said shearing member assumes two different positions with respect to said slider, while said travel performed by said slider is the same, so that said two operating conditions are obtained with the same travel of the drive member.
A female clip to assemble weatherstrips, used in the automotive industry, to the vehicles by mounting on a connector located within the weatherstrip and then passing to a pin fixed on the vehicle body; the female clip comprising • a body having a cylindrical frame, • outer prongs formed on the lower edge at the outer surface of said body in order to assemble the body with said connector, and pass to the bottom surface of the connector thus provide interlocking between connector and the body and prevent the body from displacing, • apertures extending from the lower edge of the body to the upper edge of the body, enabling the body to stretch and spring for the passing of the mentioned outer prongs to the bottom surface of the connector, • inner prongs formed in the inner volume of the body where the pin is inserted, and those extend down from the upper edge of the body to the center of the body, and spring back from the center of the body towards the body wall when in contact with the pin-head of said pin and then come to the previous position after the pin-head is passed into the body, thus locking to the pin, and characterised in that it further comprises: • protrusions formed on the outer surface of said body between the end of said apertures and the upper edge, which prevent reverse insertion during mounting into the weatherstrip, and serve as a stopper by providing extensions towards the upper surface of the connector. • a body having a cylindrical frame, • outer prongs formed on the lower edge at the outer surface of said body in order to assemble the body with said connector, and pass to the bottom surface of the connector thus provide interlocking between connector and the body and prevent the body from displacing, • apertures extending from the lower edge of the body to the upper edge of the body, enabling the body to stretch and spring for the passing of the mentioned outer prongs to the bottom surface of the connector, • inner prongs formed in the inner volume of the body where the pin is inserted, and those extend down from the upper edge of the body to the center of the body, and spring back from the center of the body towards the body wall when in contact with the pin-head of said pin and then come to the previous position after the pin-head is passed into the body, thus locking to the pin, and characterised in that it further comprises: • protrusions formed on the outer surface of said body between the end of said apertures and the upper edge, which prevent reverse insertion during mounting into the weatherstrip, and serve as a stopper by providing extensions towards the upper surface of the connector. • protrusions formed on the outer surface of said body between the end of said apertures and the upper edge, which prevent reverse insertion during mounting into the weatherstrip, and serve as a stopper by providing extensions towards the upper surface of the connector.
Method for mounting a transmission shaft inserted into a differential housing during mounting, said differential housing having a removable protection device for a transmission seal providing tightness between the differential housing and the transmission shaft, the protection device comprising: - a longitudinally slotted cylindrical protection ring which is introduced under the transmission seal to protect it during the insertion of the shaft, - an annular flat bearing flange which flatly bears on the housing, is connected to the ring and has a radial opening following the slot of the ring, and a removal handle, - an abutment projecting axially towards the outside of the housing from the annular flat bearing flange which flatly bears on the housing, in order to arrest the insertion of the shaft in a reference position, the removal handle being attached to the end of the abutment, the method being characterized in that it comprises the following steps: - placing the protection device under the transmission seal, - inserting the transmission shaft as far as a reference position, which is reached when a collar 4b of the shaft has met the outer edge of the abutment, - removing the protection device by pulling on the handle, and in that the abutment of the protection device is disengaged from the collar by being pivoted against the housing while pulling on the handle in the direction of the housing, the protection device being removed after the disengagement of the abutment by pulling on the handle away from the housing. - a longitudinally slotted cylindrical protection ring which is introduced under the transmission seal to protect it during the insertion of the shaft, - an annular flat bearing flange which flatly bears on the housing, is connected to the ring and has a radial opening following the slot of the ring, and a removal handle, - an abutment projecting axially towards the outside of the housing from the annular flat bearing flange which flatly bears on the housing, in order to arrest the insertion of the shaft in a reference position, the removal handle being attached to the end of the abutment, - placing the protection device under the transmission seal, - inserting the transmission shaft as far as a reference position, which is reached when a collar 4b of the shaft has met the outer edge of the abutment, - removing the protection device by pulling on the handle, and in that the abutment of the protection device is disengaged from the collar by being pivoted against the housing while pulling on the handle in the direction of the housing, the protection device being removed after the disengagement of the abutment by pulling on the handle away from the housing.
An isolated nucleic acid molecule which encodes a human hepatitis C virus, wherein said molecule: (i) is capable of expressing said virus when transfected into cells, (ii) is capable of infectivity in vivo, (iii) comprises at least one adaptive mutation in the amino acid sequence of NS3, which is F1464L, (iv) comprises at least one adaptive mutation in the amino acid sequence of NS4A which is A1672S, and (v) comprises at least one adaptive mutation in the amino acid sequence of NS5B which is D2979G, and (vi) one of the following groups of additional adaptive mutations in the amino acid sequence: a) S399F, A970T, A1226G, I1312V, Q1773H, N1927T, C2419R, A2919T, Y2981F and F2994S, wherein the positions are according to GenBank accession number AF009606; b) S399F, A970T, A1226G, I1312V, I1326V, Q1773H, N1927T, V2198A, I2268T, C2419R, E2622D, A2919T, Y2981F and F2994S, wherein the positions are according to GenBank accession number AF009606; or c) M345T, A828V, L864R, K1052R, A1226G, S1368P, V1663A, Q1773H, G1909S, N1927T, M2105V, S2354G, V2417A, V2431I, Y2981F and F2994R, wherein the positions are according to GenBank accession number AF009606; and wherein the human hepatitis C virus is a strain of genotype 1a. (i) is capable of expressing said virus when transfected into cells, (ii) is capable of infectivity in vivo, (iii) comprises at least one adaptive mutation in the amino acid sequence of NS3, which is F1464L, (iv) comprises at least one adaptive mutation in the amino acid sequence of NS4A which is A1672S, and (v) comprises at least one adaptive mutation in the amino acid sequence of NS5B which is D2979G, and (vi) one of the following groups of additional adaptive mutations in the amino acid sequence: a) S399F, A970T, A1226G, I1312V, Q1773H, N1927T, C2419R, A2919T, Y2981F and F2994S, wherein the positions are according to GenBank accession number AF009606; b) S399F, A970T, A1226G, I1312V, I1326V, Q1773H, N1927T, V2198A, I2268T, C2419R, E2622D, A2919T, Y2981F and F2994S, wherein the positions are according to GenBank accession number AF009606; or c) M345T, A828V, L864R, K1052R, A1226G, S1368P, V1663A, Q1773H, G1909S, N1927T, M2105V, S2354G, V2417A, V2431I, Y2981F and F2994R, wherein the positions are according to GenBank accession number AF009606; and a) S399F, A970T, A1226G, I1312V, Q1773H, N1927T, C2419R, A2919T, Y2981F and F2994S, wherein the positions are according to GenBank accession number AF009606; b) S399F, A970T, A1226G, I1312V, I1326V, Q1773H, N1927T, V2198A, I2268T, C2419R, E2622D, A2919T, Y2981F and F2994S, wherein the positions are according to GenBank accession number AF009606; or c) M345T, A828V, L864R, K1052R, A1226G, S1368P, V1663A, Q1773H, G1909S, N1927T, M2105V, S2354G, V2417A, V2431I, Y2981F and F2994R, wherein the positions are according to GenBank accession number AF009606; and
A method comprising the steps of - providing an image of a field for crop plants - analyzing the image and identifying cultivation features that give information as to how the field has been cultivated by machine in the past - ascertaining at least one value for at least one working parameter with reference to the cultivation features - creating a digital cultivation map for the field, said cultivation map comprising multiple zones, with at least one feature of at least one zone matched to the at least one value ascertained for the at least one working parameter, wherein at least one cultivation feature is selected from the following list: driving tracks, driving lanes, ploughing strips, flower strips, plant separations, and wherein at least one working parameter is selected from the following list: deployment rate for a seed or for a plant protection agent. - providing an image of a field for crop plants - analyzing the image and identifying cultivation features that give information as to how the field has been cultivated by machine in the past - ascertaining at least one value for at least one working parameter with reference to the cultivation features - creating a digital cultivation map for the field, said cultivation map comprising multiple zones, with at least one feature of at least one zone matched to the at least one value ascertained for the at least one working parameter, driving tracks, driving lanes, ploughing strips, flower strips, plant separations, and wherein at least one working parameter is selected from the following list: deployment rate for a seed or for a plant protection agent.
A heat exchanger (1, 100, 200, 300, 400, 500, 600, 700) that is supplied with air from a fan, the heat exchanger (1, 100, 200, 300, 400, 500, 600, 700) comprising: a plurality of heat transfer flat tubes extending in a first direction; a first fin connected to the plurality of heat transfer flat tubes, and having a flat portion disposed between two adjacent heat transfer tubes among the plurality of the heat transfer flat tubes, the first fin extending in a second direction intersecting the first direction; wherein a length of each of the plurality of heat transfer flat tubes is longer than a length of the first fin in a flow direction of the air; a plurality of second fins joined to at least one of a windward end and a leeward end of the flat portion of the first fin, characterised in that the plurality of second fins extend in a third direction intersecting the second direction; and the heat exchanger further comprises a third fin connected to at least one of a windward end and a leeward end of at least one of the plurality of heat transfer flat tubes, the third fin extending in the third direction. a plurality of heat transfer flat tubes extending in a first direction; a first fin connected to the plurality of heat transfer flat tubes, and having a flat portion disposed between two adjacent heat transfer tubes among the plurality of the heat transfer flat tubes, the first fin extending in a second direction intersecting the first direction; wherein a length of each of the plurality of heat transfer flat tubes is longer than a length of the first fin in a flow direction of the air; a plurality of second fins joined to at least one of a windward end and a leeward end of the flat portion of the first fin, characterised in that the plurality of second fins extend in a third direction intersecting the second direction; and the heat exchanger further comprises a third fin connected to at least one of a windward end and a leeward end of at least one of the plurality of heat transfer flat tubes, the third fin extending in the third direction.
A cleaning member mounting holder for a mop (100, 100'), comprising: a shaft for mounting a cleaning member, the shaft having opposite ends, and a pair of mounting members each having a hole, the opposite ends of the shaft being mounted in the holes of the pair of mounting members, respectively, wherein at least one of the opposite ends of the shaft is movable substantially perpendicularly to the shaft axis in the holes of the pair of mounting members; wherein each of the holes is an elongated hole or a slot having a longitudinal direction; characterized in that, the cleaning member mounting holder has a first use state in which the longitudinal direction of the holes is oriented substantially at an angle of less than 45 degrees to a vertical direction, and a second use state in which the longitudinal direction of the holes is oriented substantially at an angle of less than 45 degrees to a horizontal direction. a shaft for mounting a cleaning member, the shaft having opposite ends, and a pair of mounting members each having a hole, the opposite ends of the shaft being mounted in the holes of the pair of mounting members, respectively, wherein at least one of the opposite ends of the shaft is movable substantially perpendicularly to the shaft axis in the holes of the pair of mounting members; wherein each of the holes is an elongated hole or a slot having a longitudinal direction; characterized in that, the cleaning member mounting holder has a first use state in which the longitudinal direction of the holes is oriented substantially at an angle of less than 45 degrees to a vertical direction, and a second use state in which the longitudinal direction of the holes is oriented substantially at an angle of less than 45 degrees to a horizontal direction.
A composition comprising A- poly(vinyl alcohol) (PVOH) in an amount ranging between 30 and 99 wt%; B- at least one crosslinking compound being present in an amount ranging between 0.1 and 20 wt%, and selected from polymers, copolymers and nonpolymeric materials, each having a functionality capable of associating to the PVOH, wherein said functionality is a carboxylic acid selected from dicarboxylic acids, tricarboxylic acids and higher homologues; C- at least one additional bioplastic that is a biodegradable polymer in an amount ranging between 0.1 and 50 wt%, wherein the at least one additional bioplastic is selected from poly(ethylene oxide), poly(ethylene glycol), polycaprolactone, poly(lactic acid), cellulose and cellulose derivatives, starch, thermoplastic starch, chitosan and polyhydroxyalkanoates (PHAs); and D- optionally at least one additive in an amount ranging between 0.1 and 20 wt%. A- poly(vinyl alcohol) (PVOH) in an amount ranging between 30 and 99 wt%; B- at least one crosslinking compound being present in an amount ranging between 0.1 and 20 wt%, and selected from polymers, copolymers and nonpolymeric materials, each having a functionality capable of associating to the PVOH, wherein said functionality is a carboxylic acid selected from dicarboxylic acids, tricarboxylic acids and higher homologues; C- at least one additional bioplastic that is a biodegradable polymer in an amount ranging between 0.1 and 50 wt%, wherein the at least one additional bioplastic is selected from poly(ethylene oxide), poly(ethylene glycol), polycaprolactone, poly(lactic acid), cellulose and cellulose derivatives, starch, thermoplastic starch, chitosan and polyhydroxyalkanoates (PHAs); and D- optionally at least one additive in an amount ranging between 0.1 and 20 wt%.
Piston of an internal combustion engine, formed by an upper part joined to a lower part, wherein the lower part is formed by opposing connecting walls which are set back and inclined relative to the outer diameter of the piston, wherein in each case one connecting wall has a pin bore and the respective end of each connecting wall merges into a piston skirt, wherein the lower part has at least one recess facing in the direction of the upper part and the upper part has at least one recess facing in the direction of the lower part, wherein the recesses (5, 12) overlap after joining, wherein furthermore a permanent connection between the lower part and the upper part is a positive connection and the positive connection is formed by at least one tongue and at least one groove which can be brought into operative connection therewith, and wherein the at least one recess of the lower part is arranged above and outside the connecting wall.
An oral care composition comprising: (i) a calcium-based abrasive: (ii) a polyethylene glycol having an average molecular weight ranging from 1500 to 6000 daltons in an amount of 0.1 wt% to 0.3 wt%; (iii) an anti-bacterial agent; and (iv) an orally acceptable vehicle, wherein the anti-bacterial agent is a halogenated diphenyl ether. (i) a calcium-based abrasive: (ii) a polyethylene glycol having an average molecular weight ranging from 1500 to 6000 daltons in an amount of 0.1 wt% to 0.3 wt%; (iii) an anti-bacterial agent; and (iv) an orally acceptable vehicle,