A method of anti-seismic protection of frames and filling walls in framed buildings wherein a polyurethane-based cushioning layer is applied between the skeleton frame and at least vertical surfaces of the filling wall adjacent to the skeleton frame, characterised in that in order to apply the cushioning layer the condition of the existing filling wall is inspected and the damages if any are repaired, followed by the following subsequent stages of seismic protection: a) tight closing sheets made of thin, up to 2 mm thick, glass fibre mesh with a mesh size not exceeding 2 cm, embedded in polyurethane filler are prepared; b) a gap having width of 1 to 3 cm, preferably 2 cm, is made around the filling wall at its two lateral edges and preferably at its upper edge, using a saw, angle grinder or cutting out such a gap, to separate the filling wall from the skeleton frame; c) the surfaces of the filling wall and the skeleton frame inside the gap are cleaned of loose particles and primed with a polyurethane primer chemically compatible with the polyurethane filler; d) if there are holes or cavities in the filling wall in the plane of the gap, these shall be closed inside the gap by gluing a closing sheet prepared in stage "a" with a polyurethane adhesive chemically compatible with the filling polyurethane; e) the closing sheets prepared in stage "a" are cut to size to cover the gap, with overlaps of at least 5 cm on both sides of the gap; f) the sealing sheets are glued with polyurethane adhesive to both external surfaces of the filling wall and the skeleton frame, closing the gap space to prevent liquid filler from flowing out of the gap, wherein the shape of the sheet is being adjusted to the gap and the edges of the filling wall and the skeleton frame adjacent to it; g) the holes are made in the surface of the sealing sheets every 10 to 50 cm, preferably every 30 cm on one side of the filling wall, and plastic tubes, preferably made of Igelit, used as packers for the application of the liquid polyurethane filler are placed therein, where the diameter of the holes being adjusted to the diameter of the plastic tubes, and these tubes being sealed with thermal adhesive at the contact with the sheet; h) injection of the liquid polyurethane filler starts at the bottom with small portions, and when the polyurethane filler appears in the higher tube, the lower tube is sealed and the injection is continued through the higher tube, and these injection operations are repeated successively until the gaps are completely filled with the liquid polyurethane filler, with the side gaps being filled first and then the upper one. a) tight closing sheets made of thin, up to 2 mm thick, glass fibre mesh with a mesh size not exceeding 2 cm, embedded in polyurethane filler are prepared; b) a gap having width of 1 to 3 cm, preferably 2 cm, is made around the filling wall at its two lateral edges and preferably at its upper edge, using a saw, angle grinder or cutting out such a gap, to separate the filling wall from the skeleton frame; c) the surfaces of the filling wall and the skeleton frame inside the gap are cleaned of loose particles and primed with a polyurethane primer chemically compatible with the polyurethane filler; d) if there are holes or cavities in the filling wall in the plane of the gap, these shall be closed inside the gap by gluing a closing sheet prepared in stage "a" with a polyurethane adhesive chemically compatible with the filling polyurethane; e) the closing sheets prepared in stage "a" are cut to size to cover the gap, with overlaps of at least 5 cm on both sides of the gap; f) the sealing sheets are glued with polyurethane adhesive to both external surfaces of the filling wall and the skeleton frame, closing the gap space to prevent liquid filler from flowing out of the gap, wherein the shape of the sheet is being adjusted to the gap and the edges of the filling wall and the skeleton frame adjacent to it; g) the holes are made in the surface of the sealing sheets every 10 to 50 cm, preferably every 30 cm on one side of the filling wall, and plastic tubes, preferably made of Igelit, used as packers for the application of the liquid polyurethane filler are placed therein, where the diameter of the holes being adjusted to the diameter of the plastic tubes, and these tubes being sealed with thermal adhesive at the contact with the sheet; h) injection of the liquid polyurethane filler starts at the bottom with small portions, and when the polyurethane filler appears in the higher tube, the lower tube is sealed and the injection is continued through the higher tube, and these injection operations are repeated successively until the gaps are completely filled with the liquid polyurethane filler, with the side gaps being filled first and then the upper one.