A compound according to formula wherein X is phenyl; R 1 and R 2 are independently selected from the group consisting of H, OH, -(C 1 -C 6)alkyl-OH, halo, NH 2, NOH, NHOH, and CN; or R 1 and R 2, if bound to adjacent carbon atoms, in combination with the existing carbon-carbon bond represent a double bond between the adjacent carbon atoms; R 3 and R 4 are independently selected from the group consisting of H, (C 1- C 6)alkyl, (C 3- C 8)cycloalkyl, (C 1- C 6)haloalkyl, CN, and halo; wherein one of R 3 and R 4 is -CF 3; m is 1; W is CH 2, O or, NH; V is selected from the group consisting of H, (C 1 -C 10)alkyl, (C 2 -C 12)alkenyl, -(C 1 -C 10)alkyl-(C 6 -C 10)aryl, -(C 2 -C 12)alkenyl-(C 6 -C 10)aryl, -(C 1 -C 10)alkyl-(C 6 -C 10)aryl-(C 1 -C 10)alkyl,-(C 1 -C 10)alkyl-(C 3 -C 8)cycloalkyl, -(C 1 -C 10)alkyl-heterocyclyl containing from 1 to 3 ring heteroatoms selected from N, O, and S; wherein any aryl is optionally fused to (C 6 -C 10)aryl, (C 3 -C 8)cycloalkyl, or heterocyclyl containing from 1 to 3 ring heteroatoms selected from N, O, and S wherein any alkyl, alkenyl, cycloalkyl, heterocyclyl, or aryl is optionally substituted by 1 - 4 substituents independently selected from the group consisting of F, Cl, Br, (C 1 -C 6)alkyl, -O-(C 1 -C 6)alkyl, (C 2 -C 6)alkenyl, (C 1 -C 6)haloalkyl, (C 6 -C 10)aryl, and CN; Y 1 is N; Y 2 is N and Y 3 is O, or Y 2 is O and Y 3 is N; or a pharmaceutically acceptable salt thereof. X is phenyl; R 1 and R 2 are independently selected from the group consisting of H, OH, -(C 1 -C 6)alkyl-OH, halo, NH 2, NOH, NHOH, and CN; or R 1 and R 2, if bound to adjacent carbon atoms, in combination with the existing carbon-carbon bond represent a double bond between the adjacent carbon atoms; R 3 and R 4 are independently selected from the group consisting of H, (C 1- C 6)alkyl, (C 3- C 8)cycloalkyl, (C 1- C 6)haloalkyl, CN, and halo; wherein one of R 3 and R 4 is -CF 3; m is 1; W is CH 2, O or, NH; V is selected from the group consisting of H, (C 1 -C 10)alkyl, (C 2 -C 12)alkenyl, -(C 1 -C 10)alkyl-(C 6 -C 10)aryl, -(C 2 -C 12)alkenyl-(C 6 -C 10)aryl, -(C 1 -C 10)alkyl-(C 6 -C 10)aryl-(C 1 -C 10)alkyl,-(C 1 -C 10)alkyl-(C 3 -C 8)cycloalkyl, -(C 1 -C 10)alkyl-heterocyclyl containing from 1 to 3 ring heteroatoms selected from N, O, and S; wherein any aryl is optionally fused to (C 6 -C 10)aryl, (C 3 -C 8)cycloalkyl, or heterocyclyl containing from 1 to 3 ring heteroatoms selected from N, O, and S wherein any alkyl, alkenyl, cycloalkyl, heterocyclyl, or aryl is optionally substituted by 1 - 4 substituents independently selected from the group consisting of F, Cl, Br, (C 1 -C 6)alkyl, -O-(C 1 -C 6)alkyl, (C 2 -C 6)alkenyl, (C 1 -C 6)haloalkyl, (C 6 -C 10)aryl, and CN; wherein any aryl is optionally fused to (C 6 -C 10)aryl, (C 3 -C 8)cycloalkyl, or heterocyclyl containing from 1 to 3 ring heteroatoms selected from N, O, and S wherein any alkyl, alkenyl, cycloalkyl, heterocyclyl, or aryl is optionally substituted by 1 - 4 substituents independently selected from the group consisting of F, Cl, Br, (C 1 -C 6)alkyl, -O-(C 1 -C 6)alkyl, (C 2 -C 6)alkenyl, (C 1 -C 6)haloalkyl, (C 6 -C 10)aryl, and CN; Y 1 is N; Y 2 is N and Y 3 is O, or Y 2 is O and Y 3 is N;