A central venous catheter, comprising: a main shaft having a proximal end and a distal end, the distal end configured for placement inside a patient, the main shaft having a working lumen (201a, 201b, 201c); an infusion shaft having a proximal end and a distal end, the infusion shaft having a working lumen (308, 308a, 308b); a first optical fiber (205, 301, 302, 337a-c, 338a-c) having a length and being configured to emit bacterial disinfecting light; a hub having a proximal end and a distal end, the distal end of the infusion shaft (390a, 390b, 390c) being coupled to the proximal end of the main shaft by a conduit (460a, 460b, 460c) located inside the hub, the conduit fluidly connecting the working lumen of the infusion shaft with the working lumen of the main shaft, the hub having a first channel (407, 409, 410a, 410b, 410c, 412, 416, 420, 422, 423a, 423b, 427) that houses at least a portion of the length of the first optical fiber, the first channel being located outside the conduit, the conduit (460a, 460b, 460c) comprising a tubular body; characterized by: the conduit (460a, 460b, 460c) being transparent or translucent to the bacterial disinfecting light; and the first optical fiber having a minimum bending radius, the first channel having a length and one or more bends along the length, each of the one or more bends having a radius of curvature that is equal to or greater than the minimum bending radius of the first optical fiber. a main shaft having a proximal end and a distal end, the distal end configured for placement inside a patient, the main shaft having a working lumen (201a, 201b, 201c); an infusion shaft having a proximal end and a distal end, the infusion shaft having a working lumen (308, 308a, 308b); a first optical fiber (205, 301, 302, 337a-c, 338a-c) having a length and being configured to emit bacterial disinfecting light; a hub having a proximal end and a distal end, the distal end of the infusion shaft (390a, 390b, 390c) being coupled to the proximal end of the main shaft by a conduit (460a, 460b, 460c) located inside the hub, the conduit fluidly connecting the working lumen of the infusion shaft with the working lumen of the main shaft, the hub having a first channel (407, 409, 410a, 410b, 410c, 412, 416, 420, 422, 423a, 423b, 427) that houses at least a portion of the length of the first optical fiber, the first channel being located outside the conduit, the conduit (460a, 460b, 460c) comprising a tubular body; characterized by: the conduit (460a, 460b, 460c) being transparent or translucent to the bacterial disinfecting light; and the first optical fiber having a minimum bending radius, the first channel having a length and one or more bends along the length, each of the one or more bends having a radius of curvature that is equal to or greater than the minimum bending radius of the first optical fiber. the conduit (460a, 460b, 460c) being transparent or translucent to the bacterial disinfecting light; and the first optical fiber having a minimum bending radius, the first channel having a length and one or more bends along the length, each of the one or more bends having a radius of curvature that is equal to or greater than the minimum bending radius of the first optical fiber.