An infusion pump for delivering an intravenous ("IV") fluid comprising: a housing including an actuation area configured to engage a first portion of an IV tube in a vertical orientation, the actuation area including a first end to receive the IV tube from a fluid container and a second end to provide the IV tube to a patient, and a seal section located along a perimeter of at least a portion of the actuation area, the seal section including a gasket rib positioned along the seal section, and a tube channel located at a top portion of the housing and having a horizontal orientation, the tube channel configured to cradle a second portion of the IV tube; and a door connected to the housing and configured to engage the gasket rib to enclose the actuation area of the housing, the door including at least one of a recess section configured to align with the tube channel when the door is closed, the recess section configured to cradle the second portion of the IV tube such that the recess section and tube channel together enclose the second portion of the IV tube, or a channel relief lip configured to engage the second portion of the IV tube entering the door. a housing including an actuation area configured to engage a first portion of an IV tube in a vertical orientation, the actuation area including a first end to receive the IV tube from a fluid container and a second end to provide the IV tube to a patient, and a seal section located along a perimeter of at least a portion of the actuation area, the seal section including a gasket rib positioned along the seal section, and a tube channel located at a top portion of the housing and having a horizontal orientation, the tube channel configured to cradle a second portion of the IV tube; and an actuation area configured to engage a first portion of an IV tube in a vertical orientation, the actuation area including a first end to receive the IV tube from a fluid container and a second end to provide the IV tube to a patient, and a seal section located along a perimeter of at least a portion of the actuation area, the seal section including a gasket rib positioned along the seal section, and a tube channel located at a top portion of the housing and having a horizontal orientation, the tube channel configured to cradle a second portion of the IV tube; and a gasket rib positioned along the seal section, and a tube channel located at a top portion of the housing and having a horizontal orientation, the tube channel configured to cradle a second portion of the IV tube; and a door connected to the housing and configured to engage the gasket rib to enclose the actuation area of the housing, the door including at least one of a recess section configured to align with the tube channel when the door is closed, the recess section configured to cradle the second portion of the IV tube such that the recess section and tube channel together enclose the second portion of the IV tube, or a channel relief lip configured to engage the second portion of the IV tube entering the door. a recess section configured to align with the tube channel when the door is closed, the recess section configured to cradle the second portion of the IV tube such that the recess section and tube channel together enclose the second portion of the IV tube, or a channel relief lip configured to engage the second portion of the IV tube entering the door.