A compound of formula, where: R 1, R 2 and R 3 independently of one another are H or a C 1 -C 3 alkyl optionally substituted by a C 1 -C 3 alkoxy or C 1 -C 3 hydroxyalkoxy group, or by a phenyl ring; Y 1, Y 2 and Y 3 independently of one another are a group of formula -PO(OR') 2, -PO(R 4)(OR'), or -COOR', with the proviso that at least one of them is -PO(OR') 2 or -PO(R 4)(OR'); in which: R' independently of one another is H or C 1 -C 5 alkyl; R 4 is an phenyl or a cycloalkyl ring, or a C 1 -C 5 alkyl which is optionally substituted by an aryl or cycloalkyl ring; L is a direct bond, and Z is selected from the group consisting of: a substituted phenyl; a C 1 -C 6 alkyl chain, that is optionally interrupted by one or more oxygen -O-atom(s), and is substituted by a group of formula -O-(CH 2) m -Ar; and a C 1 -C 6 alkyl comprising a substituent group selected from the groups of formula -NHSO 2 R 5, -NHC NHR 6, -NHC OR 7 or -NR 8 R 9; where: Ar is phenyl; m is 0, or 1; R 5 is a phenyl ring; R 6 is C 1 -C 5 alkyl, optionally substituted with a phenyl or a cycloalkyl ring; or a phenyl or cycloalkyl ring; R 7 is C 1 -C 5 alkyl, optionally interrupted by one or more oxygen atoms and optionally substituted by a phenyl or a cycloalkyl ring; or a phenyl or cycloalkyl ring; R 8 is a phenyl or cycloalkyl ring; or a C 1 -C 3 alkyl substituted by a phenyl or cycloalkyl ring; R 9 is H, or a group of formula -(CH 2) n PO(OR') 2, -(CH 2) n PO(R 4)(OR') or -(CH 2) p COOR'; or L is a -(CH 2) n - chain, where n is 1, 2 or 3, and Z is a macrocyclic residue of formula -W-G-W'-T; where: W and W' the same or different from one another, are a bifunctional group selected from -O-, -S 2 NH-, -NHS 2 -, -CONH-, and -NHCO-; G is a phenylene -C 6 H 4 -, or a linear or branched C 1 -C 5 alkylene optionally interrupted by one or more oxygen atoms and optionally substituted by one or more groups selected from hydroxyl, carboxyl, C 1 -C 3 alkoxy, and a phenyl ring; and T is a macrocyclic residue of formula where: Y 1 ', Y 2 ' and Y 3 ' independently of one another are a group of formula -COOR', -PO(OR') 2, or -PO(R 4)(OR'); and the dashed line represents the linking bond with the rest of the molecule; and the individual diastereoisomers and their racemic mixtures, geometric isomers and solved enantiomers of the same, and the physiologically acceptable salt thereof. R 1, R 2 and R 3 independently of one another are H or a C 1 -C 3 alkyl optionally substituted by a C 1 -C 3 alkoxy or C 1 -C 3 hydroxyalkoxy group, or by a phenyl ring; Y 1, Y 2 and Y 3 independently of one another are a group of formula -PO(OR') 2, -PO(R 4)(OR'), or -COOR', with the proviso that at least one of them is -PO(OR') 2 or -PO(R 4)(OR'); in which: R' independently of one another is H or C 1 -C 5 alkyl; R 4 is an phenyl or a cycloalkyl ring, or a C 1 -C 5 alkyl which is optionally substituted by an aryl or cycloalkyl ring; L is a direct bond, and Z is selected from the group consisting of: a substituted phenyl; a C 1 -C 6 alkyl chain, that is optionally interrupted by one or more oxygen -O-atom(s), and is substituted by a group of formula -O-(CH 2) m -Ar; and a C 1 -C 6 alkyl comprising a substituent group selected from the groups of formula -NHSO 2 R 5, -NHC NHR 6, -NHC OR 7 or -NR 8 R 9; where: Ar is phenyl; m is 0, or 1; R 5 is a phenyl ring; R 6 is C 1 -C 5 alkyl, optionally substituted with a phenyl or a cycloalkyl ring; or a phenyl or cycloalkyl ring; R 7 is C 1 -C 5 alkyl, optionally interrupted by one or more oxygen atoms and optionally substituted by a phenyl or a cycloalkyl ring; or a phenyl or cycloalkyl ring; R 8 is a phenyl or cycloalkyl ring; or a C 1 -C 3 alkyl substituted by a phenyl or cycloalkyl ring; R 9 is H, or a group of formula -(CH 2) n PO(OR') 2, -(CH 2) n PO(R 4)(OR') or -(CH 2) p COOR'; or L is a -(CH 2) n - chain, where n is 1, 2 or 3, and Z is a macrocyclic residue of formula -W-G-W'-T; where: W and W' the same or different from one another, are a bifunctional group selected from -O-, -S 2 NH-, -NHS 2 -, -CONH-, and -NHCO-; G is a phenylene -C 6 H 4 -, or a linear or branched C 1 -C 5 alkylene optionally interrupted by one or more oxygen atoms and optionally substituted by one or more groups selected from hydroxyl, carboxyl, C 1 -C 3 alkoxy, and a phenyl ring; and T is a macrocyclic residue of formula