mhurhangee/ep-ind-claims huggingface dataset:
Patient data sensor device (1; 16) - with an implantable patient data sensor, - with an implantable data transmission mechanism, which is in signal connection with the patient data sensor, - wherein the data transmission mechanism - - has an antenna for telemetric data transmission to an external data collection unit, - - a carrier plate (5, 7) for electronic components (9, 10), - wherein the antenna is arranged in an edge region of the carrier plate (5, 7) and is configured running around the latter and around the electronic components (9, 10), - wherein the electronic components (9, 10) on the carrier plate (5, 7) are covered at least to one side by a cover, characterised in that - the carrier plate (5, 7) has two carrier layers, which are formed by a flexible board and a rigid board, which is placed on said flexible board and connected thereto, wherein the electronic components (9, 10) are attached to said rigid board, - the flexible board in a peripheral edge region projects over the rigid board, - the at least one cover is connected to the flexible board of the carrier plate (5, 7), - the antenna is configured as part of a flexible antenna layer, which is located on the edge region of the flexible board to adapt, in terms of shape, the sensor device (1, 16) in the outer region, when implanted, to the cranial bone, on which the sensor device (1, 16) rests, - the patient data sensor device (1, 16) is configured as a brain parameter sensor device. - with an implantable patient data sensor, - with an implantable data transmission mechanism, which is in signal connection with the patient data sensor, - wherein the data transmission mechanism - - has an antenna for telemetric data transmission to an external data collection unit, - - a carrier plate (5, 7) for electronic components (9, 10), - - has an antenna for telemetric data transmission to an external data collection unit, - - a carrier plate (5, 7) for electronic components (9, 10), - wherein the antenna is arranged in an edge region of the carrier plate (5, 7) and is configured running around the latter and around the electronic components (9, 10), - wherein the electronic components (9, 10) on the carrier plate (5, 7) are covered at least to one side by a cover, - the carrier plate (5, 7) has two carrier layers, which are formed by a flexible board and a rigid board, which is placed on said flexible board and connected thereto, wherein the electronic components (9, 10) are attached to said rigid board, - the flexible board in a peripheral edge region projects over the rigid board, - the at least one cover is connected to the flexible board of the carrier plate (5, 7), - the antenna is configured as part of a flexible antenna layer, which is located on the edge region of the flexible board to adapt, in terms of shape, the sensor device (1, 16) in the outer region, when implanted, to the cranial bone, on which the sensor device (1, 16) rests, - the patient data sensor device (1, 16) is configured as a brain parameter sensor device.
An exercise device comprising: a first material portion having a first face and a second face disposed opposite the first face; a second material portion having a third face and a fourth face disposed opposite the third face; and a plurality of joining regions, wherein the first material portion and the second material portion are made of a natural rubber material or a thermoplastic elastomeric material, and wherein the second face of the first material portion attaches to the third face of the second material portion at each joining region, via heat bonding, radio frequency or ultrasonic welding such that each joining region is capable of simultaneous multidimensional stretching when subjected to or released from an applied load. a first material portion having a first face and a second face disposed opposite the first face; a second material portion having a third face and a fourth face disposed opposite the third face; and a plurality of joining regions, wherein the first material portion and the second material portion are made of a natural rubber material or a thermoplastic elastomeric material, and wherein the second face of the first material portion attaches to the third face of the second material portion at each joining region, via heat bonding, radio frequency or ultrasonic welding such that each joining region is capable of simultaneous multidimensional stretching when subjected to or released from an applied load.
A wiper system for a vehicle windshield, the wiper system comprising - a first wiper arm and a second wiper arm, the first and second wiper arms being movable in at least a vertical direction; and - a horizontal wiper arrangement comprising a wiper blade arranged to wipe the surface of the vehicle windshield, the horizontal wiper arrangement further comprising a horizontally extending wiper guide element connected to the wiper blade for arranging the wiper blade to extend between vertical end sides (502, 504) of the vehicle windshield, the first and second wiper arms being connected to the horizontally extending wiper guide element for vertically moving the horizontal wiper arrangement between a vertically lower position of the vehicle windshield and a vertically higher position of the vehicle windshield; characterized in that the wiper system further comprises a plurality of spring elements connecting the wiper blade to the horizontally extending wiper guide element, the plurality of spring elements being spaced apart from each other along the length of the horizontally extending wiper guide element, wherein the spring elements are arranged to force the wiper blade towards the windshield in a horizontal direction perpendicular to the direction of the horizontally extending wiper guide element, wherein the wiper blade is connected to the horizontally extending wiper guide element at an angle (α) in a vertically downward direction from a center portion of the horizontally extending wiper guide element towards an end portion thereof. - a first wiper arm and a second wiper arm, the first and second wiper arms being movable in at least a vertical direction; and - a horizontal wiper arrangement comprising a wiper blade arranged to wipe the surface of the vehicle windshield, the horizontal wiper arrangement further comprising a horizontally extending wiper guide element connected to the wiper blade for arranging the wiper blade to extend between vertical end sides (502, 504) of the vehicle windshield, the first and second wiper arms being connected to the horizontally extending wiper guide element for vertically moving the horizontal wiper arrangement between a vertically lower position of the vehicle windshield and a vertically higher position of the vehicle windshield; characterized in that the wiper system further comprises a plurality of spring elements connecting the wiper blade to the horizontally extending wiper guide element, the plurality of spring elements being spaced apart from each other along the length of the horizontally extending wiper guide element, wherein the spring elements are arranged to force the wiper blade towards the windshield in a horizontal direction perpendicular to the direction of the horizontally extending wiper guide element, wherein the wiper blade is connected to the horizontally extending wiper guide element at an angle (α) in a vertically downward direction from a center portion of the horizontally extending wiper guide element towards an end portion thereof.
EP4 antagonist in combination with a therapy for use in the treatment of cancer wherein said therapy is PD1 antibody therapy, and wherein said EP4 antagonist is the following compound: or a pharmaceutically acceptable salt thereof, and wherein the cancer is selected from the group consisting of breast cancer, cervical cancer, colorectal cancer, endometrial cancer, glioblastoma, head and neck cancer, kidney cancer, liver cancer, lung cancer, medulloblastoma, ovarian cancer, pancreatic cancers prostate cancers, skin cancer and urinary tract cancer.
Process for the continuous preparation of light acrylate chosen from methyl acrylate and ethyl acrylate by reaction of the corresponding light alcohol chosen from methanol and ethanol with a stream of crude ester-grade acrylic acid, in the presence of at least one acid catalyst and of at least one polymerization inhibitor, in a reaction zone comprising a reactor connected to a distillation unit, characterized in that: - the stream of crude ester-grade acrylic acid comprises acrylic acid oligomers at a content by weight of greater than 8%; - the molar ratio of alcohol with respect to the acrylic acid contained in the monomer, dimer or trimer form in the stream of crude ester-grade acrylic acid is between 1.2 and 1.5, preferably between 1.3 and 1.45; - the temperature of the reactor is greater than 130°C, preferably of between 135°C and 155°C; - the concentration by weight of acid catalyst is kept greater than 2.5%, preferably of between 3% and 5%, in the reaction medium; - the concentration of polymerization inhibitor in the reactor is adjusted to a value of greater than 50 ppm, preferably of greater than 100 ppm; - an excess of light acrylate formed in the reactor is maintained; - the effluent exiting from the distillation unit is subjected to a treatment and purification line resulting in a purified light acrylate being obtained; - a residence time of the reaction residue in the reactor of greater than 50 hours, preferably of greater than 100 hours, is maintained. - the stream of crude ester-grade acrylic acid comprises acrylic acid oligomers at a content by weight of greater than 8%; - the molar ratio of alcohol with respect to the acrylic acid contained in the monomer, dimer or trimer form in the stream of crude ester-grade acrylic acid is between 1.2 and 1.5, preferably between 1.3 and 1.45; - the temperature of the reactor is greater than 130°C, preferably of between 135°C and 155°C; - the concentration by weight of acid catalyst is kept greater than 2.5%, preferably of between 3% and 5%, in the reaction medium; - the concentration of polymerization inhibitor in the reactor is adjusted to a value of greater than 50 ppm, preferably of greater than 100 ppm; - an excess of light acrylate formed in the reactor is maintained; - the effluent exiting from the distillation unit is subjected to a treatment and purification line resulting in a purified light acrylate being obtained; - a residence time of the reaction residue in the reactor of greater than 50 hours, preferably of greater than 100 hours, is maintained.
A method for preparing an implantable medical device, which method comprises: - providing an implantable medical device with a plurality of holes; - loading into the plurality of holes an amount of a therapeutic agent and a biodegradable polymer, which amount is sufficient to form a therapeutic agent layer; - loading into the plurality of holes an amount of a mixing layer which amount is sufficient to liquefy a portion of the therapeutic agent layer, thereby allowing a portion of the therapeutic agent layer to be disposed within the mixing layer wherein an amount of therapeutic agent contained within the mixing layer is smaller than an amount of therapeutic agent contained in the therapeutic agent layer; - repeating the previous step sequentially at least once with a substantially identical composition, whereby the layers take on a concentration gradient in the plurality of holes. - providing an implantable medical device with a plurality of holes; - loading into the plurality of holes an amount of a therapeutic agent and a biodegradable polymer, which amount is sufficient to form a therapeutic agent layer; - loading into the plurality of holes an amount of a mixing layer which amount is sufficient to liquefy a portion of the therapeutic agent layer, thereby allowing a portion of the therapeutic agent layer to be disposed within the mixing layer wherein an amount of therapeutic agent contained within the mixing layer is smaller than an amount of therapeutic agent contained in the therapeutic agent layer; - repeating the previous step sequentially at least once with a substantially identical composition, whereby the layers take on a concentration gradient in the plurality of holes.
An anti-tampering device comprising - a first threaded element having a female thread defining a screwing axis and an engaging surface for engagement with a driving tool, - a second threaded element having a male thread that is screwed into the female thread of the first threaded element, and - a protection body for preventing the driving tool from engaging the engaging surface, wherein the protection body is coupled to the first threaded element so that they are mutually blocked in a direction parallel to the screwing axis and free to spin around the screwing axis, wherein the protection body is coupled to the first threaded element by means of a retaining ring partly accommodated in an annular groove of the first threaded element and partly accommodated in an annular groove of the protection body, wherein the protection body's annular groove is realized on an internal surface of an annular wall of the protection body which surrounds at least partially the first threaded element and which has at least an open end for coupling with the first threaded element, characterized for comprising an elastomeric ring coaxially interposed between the second threaded element and the annular wall of the protection body. - a first threaded element having a female thread defining a screwing axis and an engaging surface for engagement with a driving tool, - a second threaded element having a male thread that is screwed into the female thread of the first threaded element, and - a protection body for preventing the driving tool from engaging the engaging surface, wherein the protection body is coupled to the first threaded element so that they are mutually blocked in a direction parallel to the screwing axis and free to spin around the screwing axis, wherein the protection body is coupled to the first threaded element by means of a retaining ring partly accommodated in an annular groove of the first threaded element and partly accommodated in an annular groove of the protection body, wherein the protection body's annular groove is realized on an internal surface of an annular wall of the protection body which surrounds at least partially the first threaded element and which has at least an open end for coupling with the first threaded element, characterized for comprising an elastomeric ring coaxially interposed between the second threaded element and the annular wall of the protection body.
A method for handling user data for a hearing aid user and at least one hearing aid, the at least one hearing aid having a memory for storing personal settings for alleviating a hearing loss for the hearing aid user, and including: • creating, by the hearing aid user, a user account on a remote server accessible over the Internet from an Internet enabled computer device, the user account including the personal settings for alleviating a hearing loss for the hearing aid user; • entering, by the hearing aid user, personal information into the user account and storing the entered personal information on the remote server; • setting up a wireless connection between a hearing aid and the personal communication device; characterized in that the method further comprises a step of: • identifying in the user account the personal communication device as a gateway to the Internet for the hearing aid; and • granting, by the hearing aid user, rights to a third party to modify data in a sub-set of the user account stored on the server; • loading the data in the sub-set of the user account stored on the server and modified by a third party having modification rights into a hearing aid memory by using the personal communication device as a gateway. • creating, by the hearing aid user, a user account on a remote server accessible over the Internet from an Internet enabled computer device, the user account including the personal settings for alleviating a hearing loss for the hearing aid user; • entering, by the hearing aid user, personal information into the user account and storing the entered personal information on the remote server; • setting up a wireless connection between a hearing aid and the personal communication device; characterized in that the method further comprises a step of: • identifying in the user account the personal communication device as a gateway to the Internet for the hearing aid; and • granting, by the hearing aid user, rights to a third party to modify data in a sub-set of the user account stored on the server; • loading the data in the sub-set of the user account stored on the server and modified by a third party having modification rights into a hearing aid memory by using the personal communication device as a gateway.
Lining element for use on a vehicle for covering an airbag, comprising a dimensionally stable backing layer with at least one predetermined breaking region which is delimited from a surrounding region and/or a further predetermined breaking region by at least one predetermined breaking line, wherein a multiplicity of regularly spaced predetermined breaking points is arranged along the predetermined breaking line, wherein the backing layer has a visible side and a rear side facing away from the visible side, on the visible side a decorative layer is arranged flat on the backing layer, and the multiplicity of predetermined breaking points is arranged on the visible side, characterized in that the backing layer forms at least one welding rib on its rear side, and at least some of the predetermined breaking points of the multiplicity of predetermined breaking points are arranged on the visible side of the backing layer opposite the welding rib.
A service robot for a ring spinning machine, wherein during operation said service robot is arranged displaceably along a row of spinning stations and can be stopped at a selected spinning station which requires a service operation, whereby the service robot is provided with groups (3, 4, 5, 6) of handling means coupled to drives, wherein the service robot is arranged as a vertical frame, which is provided with at least two vertical linear guides (2, 18, 20, 21), at least one of which is associated with at least two movable groups (3, 4, 5, 6) of handling means to perform service operations at the spinning station characterized in that the vertical linear guides (2, 18) are provided with an endless belt (9, 17), which is wrapped at one end of the guide (2, 18) around a drive pulley (7, 15) and at the other end of the guide (2, 18) is wrapped around a freely rotatable pulley (8, 16), whereby attached to the belt (9, 17) is a carrier (33, 55) of one group (3, 5) of handling means and, in addition, at least one other group (4, 6) of handling means is movably and disconnectably coupled to the belt (9, 17).
A combination of a self-supporting tag application device and a cartridge comprising: - a frame, and connected to that frame, - a tag application means (15, 16) for applying a tag (20, 21) to an animal at a tagging site, - supply means (31, 32, 40, 50; 30, 33, 41, 51) for sequentially supplying tags being assembled in the form of a continuous strip (200, 210) from the cartridge to the tagging site, - positioning means for automatically positioning a distal tag of the strip (200, 210) at the tagging site, wherein the cartridge is filled with the continuous strip of tags (200, 210) being wound on a reel (305,306), and a distal section of the strip, being external of the cartridge, is operatively connectable with the supply means (32, 35; 33, 35). - a frame, and connected to that frame, - a tag application means (15, 16) for applying a tag (20, 21) to an animal at a tagging site, - supply means (31, 32, 40, 50; 30, 33, 41, 51) for sequentially supplying tags being assembled in the form of a continuous strip (200, 210) from the cartridge to the tagging site, - positioning means for automatically positioning a distal tag of the strip (200, 210) at the tagging site,
A method for use in a wireless communication system, the system operative for transmitting a combination of packet data and delay sensitive data having a total available transmit power, the method comprising: establishing at least one delay sensitive communication link between a base station and a mobile station (26,28) based on a pilot signal having a pilot power; satisfying a pilot power requirement and a delay sensitive data power requirement from the total available transmit power; characterised by allocating available packet data traffic power for use by the packet data channel wherein the available packet data traffic power is that remaining after the pilot power requirement and the delay sensitive data power requirement are satisfied from the total available transmit power; and determining a packet data rate for transmission from the base station to the mobile station based on the available packet data traffic power. establishing at least one delay sensitive communication link between a base station and a mobile station (26,28) based on a pilot signal having a pilot power; satisfying a pilot power requirement and a delay sensitive data power requirement from the total available transmit power; characterised by allocating available packet data traffic power for use by the packet data channel wherein the available packet data traffic power is that remaining after the pilot power requirement and the delay sensitive data power requirement are satisfied from the total available transmit power; and determining a packet data rate for transmission from the base station to the mobile station based on the available packet data traffic power.
A storage system comprising: a plurality of storage devices; and a controller operable to manage a secondary volume, of a remote copy pair with a primary volume of another storage system, and corresponding to a portion of the plurality of storage devices, wherein the secondary volume has a function for storing data included in journal data sent from said other storage system according to a remote copy procedure, characterized in that the controller is operable to handle the journal data to be stored temporarily in a third volume corresponding to another portion of the plurality of storage devices before storing the data of the journal data to the secondary volume, if a relationship between the journal data and another journal data, which has a smaller sequence number than the sequence number of the journal data and is sent from said other storage system to the storage system, meets the condition that said journal data and said other journal data have the same restore address. a plurality of storage devices; and a controller operable to manage a secondary volume, of a remote copy pair with a primary volume of another storage system, and corresponding to a portion of the plurality of storage devices, wherein the secondary volume has a function for storing data included in journal data sent from said other storage system according to a remote copy procedure, characterized in that the controller is operable to handle the journal data to be stored temporarily in a third volume corresponding to another portion of the plurality of storage devices before storing the data of the journal data to the secondary volume, if a relationship between the journal data and another journal data, which has a smaller sequence number than the sequence number of the journal data and is sent from said other storage system to the storage system, meets the condition that said journal data and said other journal data have the same restore address.