Equipment for management of sets of interchangeable buttons which are intended to be applied or replaced in a garment, said set of interchangeable buttons comprising: a plurality of groups of said buttons, each of which group is formed by homogeneous buttons; a plurality of coupling means, designed to mate with said interchangeable buttons in order to removably fasten the latter to said garment; at least a tool (4, 5) for handling said buttons and/or coupling means during operations in which the cited buttons are applied to the above garment or removed therefrom to be replaced with others; said equipment including: - a container with multiple compartments, of which: a group of compartments composed of as many housings having the shape of a well and having such a section as to receive corresponding groups of interchangeable buttons in a prearranged manner, set in almost vertical stacks; at least another of these compartments constituted by a tray adapted to contain said coupling elements; at least another of these compartments provided to define a seat adapted to contain said tool (4, 5); - closing means, associated to said container with multiple compartments, movable between at least two positions, namely open and closed ones, in the first of which said compartments are made accessible for the withdrawal and/or placement of said interchangeable buttons, coupling means and tool (4, 5), while in the second position the compartments are protected and mutually isolated, so as to prevent the transfer of the contents of one into another and vice versa; said equipment being characterized in that said well-like housings are arranged in parallel rows, with each of the housings featuring at least two opposed grooves arranged outside of the lateral surface of the well-like housing and extended to the depth thereof, said grooves being designed to define passage areas through which a first tool for handling the afore cited buttons is adapted to pass. - a container with multiple compartments, of which: a group of compartments composed of as many housings having the shape of a well and having such a section as to receive corresponding groups of interchangeable buttons in a prearranged manner, set in almost vertical stacks; at least another of these compartments constituted by a tray adapted to contain said coupling elements; at least another of these compartments provided to define a seat adapted to contain said tool (4, 5); - closing means, associated to said container with multiple compartments, movable between at least two positions, namely open and closed ones, in the first of which said compartments are made accessible for the withdrawal and/or placement of said interchangeable buttons, coupling means and tool (4, 5), while in the second position the compartments are protected and mutually isolated, so as to prevent the transfer of the contents of one into another and vice versa; said equipment being characterized in that said well-like housings are arranged in parallel rows, with each of the housings featuring at least two opposed grooves arranged outside of the lateral surface of the well-like housing and extended to the depth thereof, said grooves being designed to define passage areas through which a first tool for handling the afore cited buttons is adapted to pass.