mhurhangee/ep-ind-claims huggingface dataset:
A recombinant yeast cell, comprising an active 3-HP pathway capable of producing 3-HP and a disruption to an endogenous gene that encodes for a pyruvate reductase, wherein: (a) the pyruvate reductase has at least 60%, e.g., at least 65%, at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 91%, at least 92%, at least 93%, at least 94%, at least 95%, at least 96%, at least 97%, at least 98%, at least 99%, or 100% sequence identity to SEQ ID NO: 205; or (b) the coding sequence of the endogenous gene encoding the pyruvate reductase has at least 60%, e.g., at least 65%, at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98%, at least 99%, or 100% sequence identity to SEQ ID NO: 204. (a) the pyruvate reductase has at least 60%, e.g., at least 65%, at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 91%, at least 92%, at least 93%, at least 94%, at least 95%, at least 96%, at least 97%, at least 98%, at least 99%, or 100% sequence identity to SEQ ID NO: 205; or (b) the coding sequence of the endogenous gene encoding the pyruvate reductase has at least 60%, e.g., at least 65%, at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98%, at least 99%, or 100% sequence identity to SEQ ID NO: 204.
A method for filling a container having a valve with a fluid from a fluid source, said valve comprising: a housing with an inlet port and an outletport, wherein said inlet port is adapted for direct or indirect connection to a fluid source and wherein said outlet port is adapted for direct or indirect connection to said container; a closing member (60, 260, 360, 460); and at least one valve member (70, 270, 370, 470) which in a first position allows fluid communication between said inlet port and said outlet port and which, in a second position, prevents fluid communication from said inlet port to said outlet port, wherein said valve member is brought into and maintained in said first position only if a static pressure difference across said valve member (70, 270, 370, 470) is below a pre-determinable first threshold; the method comprising the steps of: a) connecting the valve to said fluid source, characterised in that the method further comprises the step of: b) controlling the delivery pressure of said fluid at an inlet port of said valve such as to maintain the static pressure difference across the valve member (70, 270, 370, 470) of said valve below a pre-determined or pre-determinable first threshold. a housing with an inlet port and an outletport, wherein said inlet port is adapted for direct or indirect connection to a fluid source and wherein said outlet port is adapted for direct or indirect connection to said container; a closing member (60, 260, 360, 460); and at least one valve member (70, 270, 370, 470) which in a first position allows fluid communication between said inlet port and said outlet port and which, in a second position, prevents fluid communication from said inlet port to said outlet port, a) connecting the valve to said fluid source,
A lens moving apparatus comprising: a housing; a bobbin disposed in the housing; a magnet disposed on a side portion of the housing; a first coil disposed on an outer circumferential surface of the bobbin and configured to move the bobbin in an optical-axis direction by an interaction with the magnet; a base disposed under the housing; and a cover member comprising an upper plate and a side plate(302a-302d); and wherein the housing comprises a protruding portion protruding from an outer surface of the side portion thereof and coupled to the side plate(302a-302d) of the cover member, wherein the protruding portion extends from a lower end of the side portion of the housing toward the a lower end of the base, and wherein the lens moving apparatus further comprises a sealing member(18a, 18b) disposed between the side plate(302a-302d) and the protruding portion, characterized in that the housing comprises an indented portion formed in the protruding portion for injecting the sealing member(18a, 18b), and wherein the outer protruding portions of the housing overlaps the side plate (302a-302d) of the cover member in the optical-axis direction. a housing; a bobbin disposed in the housing; a magnet disposed on a side portion of the housing; a first coil disposed on an outer circumferential surface of the bobbin and configured to move the bobbin in an optical-axis direction by an interaction with the magnet; a base disposed under the housing; and a cover member comprising an upper plate and a side plate(302a-302d); and wherein the housing comprises a protruding portion protruding from an outer surface of the side portion thereof and coupled to the side plate(302a-302d) of the cover member, wherein the protruding portion extends from a lower end of the side portion of the housing toward the a lower end of the base, and wherein the lens moving apparatus further comprises a sealing member(18a, 18b) disposed between the side plate(302a-302d) and the protruding portion, characterized in that the housing comprises an indented portion formed in the protruding portion for injecting the sealing member(18a, 18b), and wherein the outer protruding portions of the housing overlaps the side plate (302a-302d) of the cover member in the optical-axis direction.
A method for covalent immobilisation of at least one molecule comprising at least one amino group, said method comprising the sequential steps of: a. providing a surface comprising -SH groups, b. oxidising the surface comprising -SH groups by redox reactions in the presence of at least one noble metal ion, to obtain reactive sulphur-noble metal ion clusters, c. contacting the surface with at least one molecule comprising at least one amino group to obtain a covalent binding of the at least one molecule to the surface, wherein said at least one amino group is involved in obtaining said covalent bond to the sulphur-noble metal ion cluster. a. providing a surface comprising -SH groups, b. oxidising the surface comprising -SH groups by redox reactions in the presence of at least one noble metal ion, to obtain reactive sulphur-noble metal ion clusters, c. contacting the surface with at least one molecule comprising at least one amino group to obtain a covalent binding of the at least one molecule to the surface, wherein said at least one amino group is involved in obtaining said covalent bond to the sulphur-noble metal ion cluster.
Protective structure for sporting equipment comprises a curved support rib structure of a material or material composition that is suited for injection molding, which support rib structure comprises an outer frame formed of outer support ribs and inner cells formed of support ribs, said inner cells being fitted into the interior space of the outer frame and being fixed to each other and/or to the outer frame in order to form a uniform curved mesh like or cell like support rib structure, characterized in that the material thickness of the support rib structure varies in a direction perpendicular to the curve of the support rib structure so that the material thickness is greater at the middle of the support rib structure compared to the material thickness at the edges of the support rib structure.
A trial implant system configured to be used for determining the optimal dimensions of an articulating total disc replacement implant or static interbody spacer, the trial implant system comprising: a trial implant (22; 522; 800; 950; 1100) configured to be inserted into an intervertebral space defined by a superior vertebral body and an inferior vertebral body, characterized in that the trial implant (22; 522; 800; 950; 1100) includes: a superior plate (100; 526; 804; 962; 1108) having a first mating portion that defines a first articulating interface (160, 164; 580, 584; 860; 970; 1116); and an inferior plate (104; 530; 808; 966; 1112) coupled to the superior plate, the inferior plate having a second mating portion that defines a second articulating interface (260, 276; 632, 636; 896, 900; 974; 1120) configured to interact with the first articulating interface of the superior plate such that at least one of the superior plate and the inferior plate is capable of movement relative to the other. a trial implant (22; 522; 800; 950; 1100) configured to be inserted into an intervertebral space defined by a superior vertebral body and an inferior vertebral body, characterized in that the trial implant (22; 522; 800; 950; 1100) includes: a superior plate (100; 526; 804; 962; 1108) having a first mating portion that defines a first articulating interface (160, 164; 580, 584; 860; 970; 1116); and an inferior plate (104; 530; 808; 966; 1112) coupled to the superior plate, the inferior plate having a second mating portion that defines a second articulating interface (260, 276; 632, 636; 896, 900; 974; 1120) configured to interact with the first articulating interface of the superior plate such that at least one of the superior plate and the inferior plate is capable of movement relative to the other. a superior plate (100; 526; 804; 962; 1108) having a first mating portion that defines a first articulating interface (160, 164; 580, 584; 860; 970; 1116); and an inferior plate (104; 530; 808; 966; 1112) coupled to the superior plate, the inferior plate having a second mating portion that defines a second articulating interface (260, 276; 632, 636; 896, 900; 974; 1120) configured to interact with the first articulating interface of the superior plate such that at least one of the superior plate and the inferior plate is capable of movement relative to the other.
A nailing machine comprising: a driver driven by an impact mechanism in a housing; a nose portion including an ejection opening for slidably guiding the driver and an aperture opened to direct to a rear side of the ejection opening; a nail supply guide formed continuously to and integrally with a side edge of the aperture; a nail supply mechanism that is reciprocatively movable along the nail supply guide and supplies a foremost one of connected nails from the aperture into the ejection opening; characterized by a contact nose, including an ejection opening coaxially formed with the ejection opening of the nose portion, connected to a bottom of a contact arm and urged to a direction of an end portion of the ejection opening by downwardly pushing the contact arm; a nose holder attached to a bottom part of the nose portion, wherein the contact nose is held within the nose holder so as to be slidable along a direction in which the nail is hammered; and a guide slope, formed at an upper rear side of the ejection opening of the contact nose, for guiding a tip end of a nail that is hammered out tiltingly from the ejection opening of the nose portion to a rear side. a driver driven by an impact mechanism in a housing; a nose portion including an ejection opening for slidably guiding the driver and an aperture opened to direct to a rear side of the ejection opening; a nail supply guide formed continuously to and integrally with a side edge of the aperture; a nail supply mechanism that is reciprocatively movable along the nail supply guide and supplies a foremost one of connected nails from the aperture into the ejection opening; characterized by a contact nose, including an ejection opening coaxially formed with the ejection opening of the nose portion, connected to a bottom of a contact arm and urged to a direction of an end portion of the ejection opening by downwardly pushing the contact arm; a nose holder attached to a bottom part of the nose portion, wherein the contact nose is held within the nose holder so as to be slidable along a direction in which the nail is hammered; and a guide slope, formed at an upper rear side of the ejection opening of the contact nose, for guiding a tip end of a nail that is hammered out tiltingly from the ejection opening of the nose portion to a rear side.
A measurement system comprising: a first voltage measurement unit, which measures a first voltage as a line voltage between a first phase and a second phase of a three-phase power line configured by three phases including the first phase, the second phase, and a third phase; a first current measurement unit, which measures a first current as a current of the first phase; a third current measurement unit, which measures a third current as a current of the third phase; a determination unit, which determines a direction of rotation of the three phases on the basis of the first voltage and the first current; characterized in that the measurement system further comprises a computation unit, which, on the basis of at least the determination of the direction of rotation by the determination unit, computes a change in a current phase due to a load device in each of the first current, the third current, and a second current as a current of the second phase. a first voltage measurement unit, which measures a first voltage as a line voltage between a first phase and a second phase of a three-phase power line configured by three phases including the first phase, the second phase, and a third phase; a first current measurement unit, which measures a first current as a current of the first phase; a third current measurement unit, which measures a third current as a current of the third phase; a determination unit, which determines a direction of rotation of the three phases on the basis of the first voltage and the first current; characterized in that the measurement system further comprises a computation unit, which, on the basis of at least the determination of the direction of rotation by the determination unit, computes a change in a current phase due to a load device in each of the first current, the third current, and a second current as a current of the second phase.
An in vitro method for identifying a human at risk of experiencing a major adverse cardiac event, wherein said method comprises detecting the presence of a reduced level of human TGF-α polypeptide within a serum sample from a human and wherein the presence of said reduced level indicates that said human is at risk of experiencing a major adverse cardiac event.
A method for producing a kokumi flavour enhancing effect, comprising: preparing an Allium species mash; isolating at least one compound from said mash, wherein said compound is selected from the group consisting of a compound having the formula (a) or (b); where R 1 and R 2 are each independently selected from the group consisting of -CH 3, -CH 2 CH 3, -CH=CH 2, -C≡CH, -CH 2 CH 2 CH 3, -CH=CHCH 3, and -CH 2 CH=CH 2; R 3 is an L-γ-glutamyl group or a salt thereof; and R 4 is absent or O, and in the event that O is selected, the bond between R 4 and S is a double bond; purifying said compound; and combining at least one of said compounds of formula (a) or (b) with at least one inducing composition. preparing an Allium species mash; isolating at least one compound from said mash, wherein said compound is selected from the group consisting of a compound having the formula (a) or (b); where R 1 and R 2 are each independently selected from the group consisting of -CH 3, -CH 2 CH 3, -CH=CH 2, -C≡CH, -CH 2 CH 2 CH 3, -CH=CHCH 3, and -CH 2 CH=CH 2; R 3 is an L-γ-glutamyl group or a salt thereof; and R 4 is absent or O, and in the event that O is selected, the bond between R 4 and S is a double bond; where R 1 and R 2 are each independently selected from the group consisting of -CH 3, -CH 2 CH 3, -CH=CH 2, -C≡CH, -CH 2 CH 2 CH 3, -CH=CHCH 3, and -CH 2 CH=CH 2; R 3 is an L-γ-glutamyl group or a salt thereof; and R 4 is absent or O, and in the event that O is selected, the bond between R 4 and S is a double bond; purifying said compound; and combining at least one of said compounds of formula (a) or (b) with at least one inducing composition.
Re-configurable type tooling system for supporting and positioning a body to be machined, said tooling system comprising: - a reference plane; - a plurality of re-configurable elements, in particular of the column type, comprising a first portion suitable for positioning the re-configurable element on the reference plane and fitted with magnetic stopping means, and a second portion which is movable perpendicularly to said reference plane and to said first portion; - moving means for moving said re-configurable elements relative to the reference plane; characterized in that said moving means comprise a sliding system located under said reference plane, said sliding system comprising at least one magnetic element adapted to interact with said magnetic stopping means of said first portion in order to move said reconfigurable elements on the reference plane. - a reference plane; - a plurality of re-configurable elements, in particular of the column type, comprising a first portion suitable for positioning the re-configurable element on the reference plane and fitted with magnetic stopping means, and a second portion which is movable perpendicularly to said reference plane and to said first portion; - moving means for moving said re-configurable elements relative to the reference plane;
Cooking compartment door of a cooking oven having a pyrolysis function, having a borosilicate glass panel as an inner panel, which on a surface is equipped at least in sections with at least one colour coat, characterised in that the colour coat is applied to the surface of the borosilicate glass panel which faces away from the cooking compartment; that an adhesion temperature, which permits an adhesion of the colour coat to the borosilicate glass panel, is at 150 to 200°C; and that the colour coat is resistant at least up to a temperature of 400°C and is not connected to the surface by means of melting, wherein the colour coat is bonded substantially to an inorganic bonding agent chosen from a soluble glass binder and/or a sol-gel binder, and wherein the colour coat comprises a pigment chosen from inorganic metal compounds.
Crawler track or crawler track segment for a crawler tracked vehicle which is suitable for running via a drive wheel and via bogie wheels, wherein the crawler track or the crawler track segment has an outer ground contact side and an inner wheel contact side, wherein the inner wheel contact side exhibits a flat surface, from which a plurality of guide horns projects to guide the crawler track or the crawler track segment during the movement of the crawler tracked vehicle, wherein at least parts of the flat surface serve as the running surface for the bogie wheels, wherein, in the flat surface, cavities (6, 6a, 6b) are provided for the engagement of drive pegs of the drive wheel, wherein the crawler track or crawler track segment exhibits cavities that do not penetrate as far as the ground contact side from the wheel contact side, wherein these cavities are in the form of channels which are oriented perpendicular to the longitudinal axis of the crawler track or the crawler track segment, characterized in that the channels extend between the guide horns over the entire width of the crawler track or crawler track segment.
Storage compartment, which is insertable into a cabinet element, which is formed from a blank of sheet metal, comprising a base part and edge regions (3, 4) surrounding the base part, which edge regions (3, 4) are bent upwards by about 90° with respect to the base part, and the upwardly bent edge regions (3, 4) are equipped with receiving and holding means, in each of which receiving and holding means a plate-shaped element is inserted and is held and forms a wall of the storage compartment, whereby one each of a first edge region and a second edge region form a corner region of the storage compartment with a first side surface and a second side surface, whereby the first side surface serves as a supporting surface for a plate side of the plate-shaped element inserted in the storage compartment, whereby the second side surface covers the frontal surface of the plate-shaped element at least over a portion of the height, into which second side surface a projecting element is provided in such a way that the inserted plate-shaped element comes to lie between supporting surface and projecting element, and the supporting surface and the projecting element form the receiving and holding means, characterized in that the projecting element is designed as crosspiece, which is formed by two parallel cuts made in the second edge region, which cuts form the longitudinal sides of the crosspiece, and which crosspiece remains connected by its narrow sides to the second edge region, and in that the crosspiece is bent up out of the surface of the second edge region.
A sole element for an article of footwear, comprising: a cleat including an interior surface, an exterior surface opposite the interior surface, and an outer flange, wherein the outer flange includes a first surface, a second surface opposite the first surface, and an outer perimeter edge extending between the first and second surfaces, wherein a plurality of perimeter openings extending through the outer flange are located adjacent the outer perimeter edge, and wherein the outer flange is flexible and formed from a nylon material; and a sole component engaged with the cleat, wherein the sole component includes a continuous layer of material that covers the outer perimeter edge, extends over the first and second surfaces of the outer flange, and through the plurality of perimeter openings to connect and permanently fix the sole component with the cleat without use of a threaded or turnbuckle connector. a cleat including an interior surface, an exterior surface opposite the interior surface, and an outer flange, wherein the outer flange includes a first surface, a second surface opposite the first surface, and an outer perimeter edge extending between the first and second surfaces, wherein a plurality of perimeter openings extending through the outer flange are located adjacent the outer perimeter edge, and wherein the outer flange is flexible and formed from a nylon material; and a sole component engaged with the cleat, wherein the sole component includes a continuous layer of material that covers the outer perimeter edge, extends over the first and second surfaces of the outer flange, and through the plurality of perimeter openings to connect and permanently fix the sole component with the cleat without use of a threaded or turnbuckle connector.