mhurhangee/ep-ind-claims huggingface dataset:
An extended soluble PH20 hyaluronidase (esPH20), wherein: the esPH20 polypeptide is active at neutral pH; the esPH20 polypeptide is soluble; and the esPH20 polypeptide is selected from among: a polypeptide that consists of the sequence of amino acids set forth as amino acid residues 36-495, 36-496, 36-497, 36-498, 36-499 or 36-500 of SEQ ID NO: 107; or a polypeptide that contains amino acid substitutions in the sequence of amino acids set forth as amino acids 36-495, 36-496, 36-497, 36-498, 36-499 or 36-500 of SEQ ID NO: 107, whereby the amino acid-substituted polypeptide consists of a sequence of amino acids that has at least 95% sequence identity with the corresponding sequence of amino acids set forth as amino acids 36-495, 36-496, 36-497, 36-498, 36-499 or 36-500 of SEQ ID NO: 107. the esPH20 polypeptide is active at neutral pH; the esPH20 polypeptide is soluble; and the esPH20 polypeptide is selected from among: a polypeptide that consists of the sequence of amino acids set forth as amino acid residues 36-495, 36-496, 36-497, 36-498, 36-499 or 36-500 of SEQ ID NO: 107; or a polypeptide that contains amino acid substitutions in the sequence of amino acids set forth as amino acids 36-495, 36-496, 36-497, 36-498, 36-499 or 36-500 of SEQ ID NO: 107, whereby the amino acid-substituted polypeptide consists of a sequence of amino acids that has at least 95% sequence identity with the corresponding sequence of amino acids set forth as amino acids 36-495, 36-496, 36-497, 36-498, 36-499 or 36-500 of SEQ ID NO: 107. a polypeptide that consists of the sequence of amino acids set forth as amino acid residues 36-495, 36-496, 36-497, 36-498, 36-499 or 36-500 of SEQ ID NO: 107; or a polypeptide that contains amino acid substitutions in the sequence of amino acids set forth as amino acids 36-495, 36-496, 36-497, 36-498, 36-499 or 36-500 of SEQ ID NO: 107, whereby the amino acid-substituted polypeptide consists of a sequence of amino acids that has at least 95% sequence identity with the corresponding sequence of amino acids set forth as amino acids 36-495, 36-496, 36-497, 36-498, 36-499 or 36-500 of SEQ ID NO: 107.
An electrophoresis apparatus, comprising: a capillary array which is configured by arraying a plurality of capillaries; a measurement light irradiation unit which irradiates with measurement light; the electrophoresis apparatus is further comprised by a first lens array which includes a plurality of first lenses which are arrayed in correspondence with the plurality of capillaries; a second lens array which includes a plurality of second lenses which are arrayed in correspondence with the plurality of capillaries; and a light receiving unit which receives light which is incident upon the capillaries via the first lens array from the measurement light irradiation unit via the second lens array, wherein the measurement light irradiation unit is equipped with a first irradiation section which irradiates the capillary array with first measurement light for absorbance measurement via the first lens array, and a second irradiation section which makes one light flux of second measurement light for fluorescence measurement incident upon the plurality of capillaries of the first capillary array without interposing the first lens array. a capillary array which is configured by arraying a plurality of capillaries; a measurement light irradiation unit which irradiates with measurement light; the electrophoresis apparatus is further comprised by a first lens array which includes a plurality of first lenses which are arrayed in correspondence with the plurality of capillaries; a second lens array which includes a plurality of second lenses which are arrayed in correspondence with the plurality of capillaries; and a light receiving unit which receives light which is incident upon the capillaries via the first lens array from the measurement light irradiation unit via the second lens array, wherein the measurement light irradiation unit is equipped with a first irradiation section which irradiates the capillary array with first measurement light for absorbance measurement via the first lens array, and a second irradiation section which makes one light flux of second measurement light for fluorescence measurement incident upon the plurality of capillaries of the first capillary array without interposing the first lens array.
A phytocomplex characterized in that it comprises Citrus Bergamia Risso et Poiteau extract, Cynara scolymus L. extract, L-ascorbic acid and phytosterols.
A flexible flat cable connecting structure connecting a flexible flat cable to a connector with an intermediate cable arranging member being arranged between the flexible flat cable and the connector, wherein the flexible flat cable comprises a plurality of rectangular conductors, the intermediate cable arranging member comprises a plurality of connector terminals arranged at an array pitch different from that of the rectangular conductors and a plurality of branch conductors are provided in parallel, the branch conductors being set to have mutually different longitudinal dimensions according to the array pitch of the connector terminals, wherein the connector terminals are formed integrally with the branch conductors at one ends of the branch conductors and the connector terminals being cut out from a raw board simultaneously with the branch conductors, and the intermediate cable arranging member being laid on the flexible flat cable so that the branch conductors and the rectangular conductors form a predetermined angle (θ), and other ends of the branch conductors of the intermediate cable arranging member being respectively connected to the rectangular conductors, characterised in that a sheath of the branch conductors is formed by resin coating, wherein the intermediate cable arranging member being laid on the flexible flat cable so that the branch conductors and the rectangular conductors form a right angle.
Dispensing head for continuous fiber reinforced fused filament type additive manufacturing, the dispensing head being configured for dispensing a material onto a substrate carrier platform of an additive manufacturing apparatus, the dispensing head comprising one or more inlets for receiving at least a strand of meltable solid material and a reinforcement fiber, at least one passage extending from the one or more receiving inlets to a dispensing outlet for dispensing the material with the reinforcement fiber to serve as build material, the at least one passage including a material passage, the dispensing head further comprising a material heating unit for liquefying the material, and drive means for driving the material through the material passage by engagement of the strand of solid material, wherein the material heating unit comprises a solid radiation body extending from the dispensing outlet at least in a direction parallel to the substrate carrier platform in use, defining a radiation face toward the substrate carrier platform, for pre-heating the substrate carrier platform or a substrate located thereon to a temperature above a melting temperature of the material, wherein the radiation body is thermally separated from the dispensing outlet for enabling dispensing of the build material at a temperature below the melting temperature.
An oligonucleotide which targets a Membrane Bound Transcription Factor Peptidase, site 1 (MBTPS1) natural antisense transcript for use as a therapeutic compound, wherein the oligonucleotide increases the expression of Membrane Bound Transcription Factor Peptidase, site 1 (MBTPS1); wherein the natural antisense transcript has the nucleic acid sequence as set forth in SEQ ID NO: 2, or a variant thereof which retains the function of the natural antisense transcript of SEQ ID NO: 2.
Device (1, 2) for dispensing a determined weight of a cosmetic product (P, Pa, Pb) into a receptacle from a reservoir (12, 22a, 22b), the device comprising at least one electromechanical dispensing member (30, 35a, 35b) chosen between a positive-displacement pump and a syringe, capable of moving an amount of cosmetic product from said reservoir installed in the device to a dispensing zone of said device where said amount of product may be transferred through a nozzle into the interior of the receptacle received in said dispensing zone, the device comprising a controller (50, 51) configured to deliver a control signal to the electromechanical member according to an error with respect to a setpoint corresponding to the determined weight of cosmetic product to be delivered, said error being determined on the basis of a weighing datum obtained by at least one weighing cell for the reservoir installed in the receiving zone, wherein the controller is a reinforcement-learning controller implementing a policy function that defines an action to be performed by the electromechanical member according to a state of the device during an operation of dispensing a cosmetic product, the state of the device comprising the weighing datum representing the weight of cosmetic product dispensed into the receptacle and the error with respect to the setpoint.
A fiber width adjustment device comprising: a feeder configured to feed a tape material in a length direction of the tape material, the tape material consisting of fibers for a fiber reinforced resin after or before the fibers are impregnated with a resin; and an adjuster having a path for the tape material, the path being formed by at least a bottom and a pair of wall surfaces, an interval of the wall surfaces decreasing gradually such that a width of the tape material which passed the path can be changed by adjusting a part of the path, the tape material passing through the part of the path while contacting with the bottom and the wall surfaces, the bottom having a convex surface, wherein the width of the tape material can be adjusted by adjusting a position where the tape material departs from the path, and wherein the adjuster is configured to adjust the position, at which the tape material departs, by moving the path in a direction parallel to a thickness direction of the tape material, the path being moveable relatively to the tape material. a feeder configured to feed a tape material in a length direction of the tape material, the tape material consisting of fibers for a fiber reinforced resin after or before the fibers are impregnated with a resin; and an adjuster having a path for the tape material, the path being formed by at least a bottom and a pair of wall surfaces, an interval of the wall surfaces decreasing gradually such that a width of the tape material which passed the path can be changed by adjusting a part of the path, the tape material passing through the part of the path while contacting with the bottom and the wall surfaces, the bottom having a convex surface, wherein the width of the tape material can be adjusted by adjusting a position where the tape material departs from the path, and wherein the adjuster is configured to adjust the position, at which the tape material departs, by moving the path in a direction parallel to a thickness direction of the tape material, the path being moveable relatively to the tape material.
A method for communicating between a motor vehicle and a diagnostic unit, which has its own means for wireless communication with the motor vehicle, wherein a wireless communication connection is established between the motor vehicle and the diagnostic unit once an authorisation of the diagnostic unit has been checked, wherein the diagnostic unit is connected to a vehicle key associated with the motor vehicle and the authorisation of the diagnostic unit is checked with the aid of authorisation data stored in the vehicle key, for which purpose authorisation data are transmitted to the diagnostic unit from the vehicle key via a communication connection between a vehicle key reading apparatus, in which the vehicle key is inserted, and the diagnostic unit, characterised in that based on the authorisation data received, a session key for an encrypted communication connection between the diagnostic unit and the motor vehicle is generated and in that the encrypted communication connection continues, once it has been successfully established, independently of whether the vehicle key remains in the vehicle key reading apparatus.
Cooking device for culinary preparations comprising: - a cooking chamber, capable of simultaneously receiving several individual culinary preparations, - a primary heating means (110a, 110b), arranged in order to deliver a thermal power called primary thermal power, making it possible to heat the cooking chamber, - a moveable plate, capable of being displaced inside the cooking chamber, and comprising a plurality of cooking sites, each being arranged in order to receive a culinary preparation, said device being characterized in that it further comprises secondary heating means, comprising a plurality of heating elements, situated above the a moveable plate, moveable inside the cooking chamber and arranged in order to follow a displacement of the moveable plate, each heating element being associated with one of the cooking sites and being arranged in order to deliver a thermal power called secondary thermal power making it possible to heat preferentially the top of this cooking site. - a cooking chamber, capable of simultaneously receiving several individual culinary preparations, - a primary heating means (110a, 110b), arranged in order to deliver a thermal power called primary thermal power, making it possible to heat the cooking chamber, - a moveable plate, capable of being displaced inside the cooking chamber, and comprising a plurality of cooking sites, each being arranged in order to receive a culinary preparation,
Filter layout for hydraulic media, particularly oil, with a filter housing as well as a filter body laid out within and a drain outlet with a screw-cap part, characterised by the fact that the screw-cap part, before reaching its screw end position in and on the assigned thread on the housing, reaches a locking position and that a latching element arranged on the screw cap part connects to the latch located on the housing with a snap that is either audible or can be felt when the screw cap part reaches a target locking position.
A liquid delivery device comprising: a liquid feeding pipe configured to include a liquid introduce port and a liquid discharge port; a housing container configured to hold liquid as a culture medium to be introduced from the liquid introduce port; a liquid feed mechanism configured to feed the liquid in the liquid feeding pipe to the liquid discharge port; a gas introduce unit configured to introduce gas into the liquid feeding pipe; a liquid level detection unit configured to detect an advancing liquid level of the liquid fed in the liquid feeding pipe; and a controller configured to control the liquid feed mechanism, the gas introduce unit, and the liquid level detection unit, wherein the gas introduce unit is connected to a branch point provided in the liquid feeding pipe on the upstream side of the liquid feed mechanism, and the liquid level detection unit is provided on the downstream side of the branch point, characterized in that the controller is configured to: return the liquid in the liquid feeding pipe on the upstream side of the branch point to the housing container due to a drop by introducing gas from the gas introduce unit into the liquid feeding pipe, and feed the liquid in the liquid feeding pipe on the downstream side of the branch point to the liquid discharge port by the liquid feed mechanism. a liquid feeding pipe configured to include a liquid introduce port and a liquid discharge port; a housing container configured to hold liquid as a culture medium to be introduced from the liquid introduce port; a liquid feed mechanism configured to feed the liquid in the liquid feeding pipe to the liquid discharge port; a gas introduce unit configured to introduce gas into the liquid feeding pipe; a liquid level detection unit configured to detect an advancing liquid level of the liquid fed in the liquid feeding pipe; and a controller configured to control the liquid feed mechanism, the gas introduce unit, and the liquid level detection unit, wherein the gas introduce unit is connected to a branch point provided in the liquid feeding pipe on the upstream side of the liquid feed mechanism, and the liquid level detection unit is provided on the downstream side of the branch point, characterized in that the controller is configured to: return the liquid in the liquid feeding pipe on the upstream side of the branch point to the housing container due to a drop by introducing gas from the gas introduce unit into the liquid feeding pipe, and feed the liquid in the liquid feeding pipe on the downstream side of the branch point to the liquid discharge port by the liquid feed mechanism. return the liquid in the liquid feeding pipe on the upstream side of the branch point to the housing container due to a drop by introducing gas from the gas introduce unit into the liquid feeding pipe, and feed the liquid in the liquid feeding pipe on the downstream side of the branch point to the liquid discharge port by the liquid feed mechanism.
Piston for an actuator, operable by fluid, in particular for a fluid-actuated linear drive, with a piston body formed in one piece, which has in the area of its radial outer periphery an annular retaining recess coaxial to the longitudinal axis of the piston and with two side recess edges (28a, 28b) facing one another, in which is held a guide band with an annular structure and which has two band end sections (22a, 22b) facing one another in the circumferential direction of the retaining recess, characterised in that the two recess edges (28a, 28b) of the retaining recess, viewed in cross-section, each have an undercut profile, wherein they each have with radial clearance from the recess base of the retaining recess an annular retaining projection (38a, 38b) extending towards the opposite recess edge (28a, 28b), which is in positive engagement with the facing side edge (37a, 37b) of the guide band, wherein the guide band is a continuous body, linear when produced and bent into an annular shape during subsequent fitting to the piston body.
A system for conveying objects, comprising: - package integrating first wireless communication means; - a computer platform including at least one database grouping, for each package, information about its conveying cycle; the computer platform being parameterized to perform a digital tracking of the time-stamped geolocation of each package based on a conveying cycle start instruction, each package carrying an electronic actuator coupled to the first wireless communication means to emit a first signal to the computer platform, said first signal being interpreted by the computer platform as a conveying cycle start instruction, the package forming a container for transporting the objects. - package integrating first wireless communication means; - a computer platform including at least one database grouping, for each package, information about its conveying cycle;
A method of manufacturing a semiconductor device, comprising: growing a source region made of silicon of the first or of the second conductivity type on a surface of a semiconductor body made of silicon carbide of the first conductivity type for directly forming a heterojunction interface between the source region and the semiconductor body; selectively oxidizing a part of the source region to make an oxidized portion reaching the heterojunction interface; removing the oxidized portion to form a trench; depositing gate insulating film made of deposited layer inside of the trench; forming a gate electrode on the gate insulating film; forming a source electrode in contact with the source region; and forming a drain electrode in contact with the semiconductor body. growing a source region made of silicon of the first or of the second conductivity type on a surface of a semiconductor body made of silicon carbide of the first conductivity type for directly forming a heterojunction interface between the source region and the semiconductor body; selectively oxidizing a part of the source region to make an oxidized portion reaching the heterojunction interface; removing the oxidized portion to form a trench; depositing gate insulating film made of deposited layer inside of the trench; forming a gate electrode on the gate insulating film; forming a source electrode in contact with the source region; and forming a drain electrode in contact with the semiconductor body.
A semiconductor memory device employing processing in memory, PIM, the semiconductor memory device comprising: a plurality of memory banks comprising a first memory bank group comprising a computation circuit (115a, 115b) and a second memory bank group without a computation circuit; and a control circuit configured to control a PIM operation by the first memory bank group to be performed together with processing of memory requests for the plurality of memory banks while satisfying a maximum power consumption condition of the semiconductor memory device, wherein the control circuit comprises a request counter configured to count memory requests for each of the plurality of memory banks according to a predetermined period, and the control circuit is configured to, based on numbers counted by the request counter, perform scheduling on the processing of the memory requests and the PIM operation, and wherein the control circuit is configured to, when a number corresponding to the second memory bank group among the numbers counted by the request counter is equal to or greater than a preset threshold value, slow down the PIM operation by the first memory bank group in order to process a memory request for the second memory bank group. a plurality of memory banks comprising a first memory bank group comprising a computation circuit (115a, 115b) and a second memory bank group without a computation circuit; and a control circuit configured to control a PIM operation by the first memory bank group to be performed together with processing of memory requests for the plurality of memory banks while satisfying a maximum power consumption condition of the semiconductor memory device, wherein the control circuit comprises a request counter configured to count memory requests for each of the plurality of memory banks according to a predetermined period, and the control circuit is configured to, based on numbers counted by the request counter, perform scheduling on the processing of the memory requests and the PIM operation, and wherein the control circuit is configured to, when a number corresponding to the second memory bank group among the numbers counted by the request counter is equal to or greater than a preset threshold value, slow down the PIM operation by the first memory bank group in order to process a memory request for the second memory bank group.
A composition for forming an insulation coating film of an oriented electrical steel sheet, comprising: a first component including a product of the condensation reaction of the composite metal phosphate and the boric acid, and a second component including at least two colloidal silica having different average particle diameters, wherein the second component has an amount of 50 to 250 parts by weight based on 100 parts by weight of the first component, and the second component includes a sodium content inevitably included as impurities of more than 0 wt% and less than 0.60 wt%. a first component including a product of the condensation reaction of the composite metal phosphate and the boric acid, and a second component including at least two colloidal silica having different average particle diameters, wherein the second component has an amount of 50 to 250 parts by weight based on 100 parts by weight of the first component, and the second component includes a sodium content inevitably included as impurities of more than 0 wt% and less than 0.60 wt%.