mhurhangee/ep-ind-claims huggingface dataset:
A method of producing an acetyl-CoA carboxylase (ACCase) enzyme that is tolerant to at least one herbicide, comprising: a. providing an ACCase-deficient yeast that comprises a nucleic acid encoding a chimeric ACCase, said chimeric ACCase comprising an N-terminal region and a C-terminal region, wherein the C-terminal region comprises an herbicide sensitivity region of a monocot plastidic ACCase of a Poaceae; b. contacting said yeast with at least one mutagenic oligonucleotide under conditions that permit site-directed mutagenesis of at least one codon of the nucleic acid encoding the chimeric ACCase, and growing the mutagenized yeast thereby forming a library of mutagenized yeast colonies; c. culturing the mutagenized yeast colonies in the presence of at least one ACCase-inhibiting herbicide to form treated colonies; and d. isolating from at least one of said treated colonies at least one mutagenized yeast that grows in the presence of the herbicide, wherein the mutagenized yeast that grows in the presence of the herbicide comprises a mutagenized ACCase that has a tolerance to the herbicide that is greater than that exhibited by the chimeric ACCase of step (a): wherein the method is a high throughput method in which a trained worker can generate and screen at least 500 different HSR-variant ACCase per month, each from its own cell colony. a. providing an ACCase-deficient yeast that comprises a nucleic acid encoding a chimeric ACCase, said chimeric ACCase comprising an N-terminal region and a C-terminal region, wherein the C-terminal region comprises an herbicide sensitivity region of a monocot plastidic ACCase of a Poaceae; b. contacting said yeast with at least one mutagenic oligonucleotide under conditions that permit site-directed mutagenesis of at least one codon of the nucleic acid encoding the chimeric ACCase, and growing the mutagenized yeast thereby forming a library of mutagenized yeast colonies; c. culturing the mutagenized yeast colonies in the presence of at least one ACCase-inhibiting herbicide to form treated colonies; and d. isolating from at least one of said treated colonies at least one mutagenized yeast that grows in the presence of the herbicide, wherein the mutagenized yeast that grows in the presence of the herbicide comprises a mutagenized ACCase that has a tolerance to the herbicide that is greater than that exhibited by the chimeric ACCase of step (a):
An arithmetic model generation system comprising: a tire information acquisition unit that is configured to acquire tire data including a temperature and pressure of a tire; a position information acquisition unit that is configured to acquire position data for a vehicle on which the tire is mounted; a wear amount calculator that includes an arithmetic model that is configured to calculate a tire wear amount based on the temperature, pressure, and position, the wear amount calculator is configured to calculate a wear amount of the tire by using the arithmetic model by inputting the tire data and the position data corresponding to the tire data; and an arithmetic model update unit that is configured to compare the wear amount measured in the tire with the wear amount calculated by the wear amount calculator and to update the arithmetic model accordingly, characterized in that the arithmetic model is also configured to calculate an uneven wear amount of the tire. a tire information acquisition unit that is configured to acquire tire data including a temperature and pressure of a tire; a position information acquisition unit that is configured to acquire position data for a vehicle on which the tire is mounted; a wear amount calculator that includes an arithmetic model that is configured to calculate a tire wear amount based on the temperature, pressure, and position, the wear amount calculator is configured to calculate a wear amount of the tire by using the arithmetic model by inputting the tire data and the position data corresponding to the tire data; and an arithmetic model update unit that is configured to compare the wear amount measured in the tire with the wear amount calculated by the wear amount calculator and to update the arithmetic model accordingly, characterized in that the arithmetic model is also configured to calculate an uneven wear amount of the tire.
A composition comprising a combination of a source of a first enzymatic active domain and a source of a second enzymatic active domain, wherein said source is protein-based or nucleic acid-based, and wherein said first and second enzymatic active domains each exhibit distinct target bond specificities and are comprised on a distinct first and second polypeptide, and wherein said first and second polypeptide comprise a different multiplicity of said first and/or second enzymatic active domain, wherein said enzymatic active domain is a domain selected from the group consisting of a cysteine, histidine-dependent amidohydrolases/peptidase domain, an endopeptidase domain, an amidase domain and a glycosylhydrolase, and wherein said second polypeptide comprises a sequence that has at least 80% sequence identity with SEQ ID NO: 70.
A laminated glazing comprising: • a first glass sheet; • at least one interlayer sheet made of thermoplastic polymer; said first glass sheet being in direct contact with said interlayer sheet; • optionally a "solar-protection" sheet or functional metal layer having reflective properties in the infrared region and/or in the solar radiation region; • optionally a second interlayer sheet when said "solar-protection" sheet is present; • a second glass sheet; and • at least one sheet of pressure-sensitive adhesive, in direct contact with a heat-sensitive functional sheet based on encapsulated liquid crystals, on electrophoretic particles dispersed in a medium, on particles dispersed in an electrophoretic fluid or on particles for the polarization of light; said second glass sheet being in direct contact with said sheet of pressure-sensitive adhesive, said sheet of pressure-sensitive adhesive and said second glass sheet being in direct contact at the external face of the latter. • a first glass sheet; • at least one interlayer sheet made of thermoplastic polymer; said first glass sheet being in direct contact with said interlayer sheet; • optionally a "solar-protection" sheet or functional metal layer having reflective properties in the infrared region and/or in the solar radiation region; • optionally a second interlayer sheet when said "solar-protection" sheet is present; • a second glass sheet; and • at least one sheet of pressure-sensitive adhesive, in direct contact with a heat-sensitive functional sheet based on encapsulated liquid crystals, on electrophoretic particles dispersed in a medium, on particles dispersed in an electrophoretic fluid or on particles for the polarization of light;
A method of delivering power to remote equipment associated with a hydraulic system, the method comprising: actuating an output voltage from a control panel at an electronic control output electrically connected at a socket positioned at a first end of a hose assembly, the hose assembly having a plurality of concentric conductive layers including a first conductive layer and a second conductive layer, the first conductive layer being electrically connected to the socket and extending the length of the hose assembly and also electrically connected to a second socket at a second end of the hose assembly, thereby delivering the output voltage to remote equipment at the second end of the hose assembly that is electrically connected to the second socket, the second conductive layer being used in combination with the first conductive layer to monitor degradation of the hose assembly in coordination with delivering the output voltage to remote equipment at the second end of the hose assembly.
A compressed air energy storage system, comprising: a compressor (106, 126, 146, 166) adapted to receive air and output compressed air; a heat transfer unit (109, 115, 129, 133, 149, 155, 169, 175) coupled to the compressor and adapted to receive the compressed air and a heat transfer medium and to output cooled air and a heated heat transfer medium; a compressed gas storage unit coupled to the heat transfer unit and adapted to receive and store the cooled air; a waste heat recovery unit (WHRU, 112, 118, 132, 138, 152, 158, 172, 178) coupled to the heat transfer unit and adapted to receive the heated heat transfer medium; a thermal mass coupled to the waste heat recovery unit and the compressed gas storage unit, the thermal mass adapted to be heated by the waste heat recovery unit, to receive the cooled air from the compressed gas storage unit, to heat the cooled air, and to output heated air; a power generation unit coupled to the thermal mass and adapted to receive the heated air and generate a power output, characterized in that it further comprises an electric heater disposed at least one of on and in the thermal mass, wherein the waste heat recovery unit is coupled to and powers the electric heater, and the electric heater heats the thermal mass. a compressor (106, 126, 146, 166) adapted to receive air and output compressed air; a heat transfer unit (109, 115, 129, 133, 149, 155, 169, 175) coupled to the compressor and adapted to receive the compressed air and a heat transfer medium and to output cooled air and a heated heat transfer medium; a compressed gas storage unit coupled to the heat transfer unit and adapted to receive and store the cooled air; a waste heat recovery unit (WHRU, 112, 118, 132, 138, 152, 158, 172, 178) coupled to the heat transfer unit and adapted to receive the heated heat transfer medium; a thermal mass coupled to the waste heat recovery unit and the compressed gas storage unit, the thermal mass adapted to be heated by the waste heat recovery unit, to receive the cooled air from the compressed gas storage unit, to heat the cooled air, and to output heated air; a power generation unit coupled to the thermal mass and adapted to receive the heated air and generate a power output, characterized in that it further comprises an electric heater disposed at least one of on and in the thermal mass, wherein the waste heat recovery unit is coupled to and powers the electric heater, and the electric heater heats the thermal mass.
Supporting structure, in particular for a wind power plant, with - at least two partial segments which are at least partially connected to one another and are each formed from a metal plate having a longitudinal extension and a widthwise extension, the longitudinal extension being greater than the width extension, and wherein - the partial segments each have longitudinal edges (8a, b) extending in the longitudinal extension and are joined to one another along the longitudinal edges (8a, b) by means of a welded joint in each case, - the partial segments each have end edges (10a, b) extending in widthwise extension, the partial segments each being bent along their end edges (10a, b), characterized in that - the respective welded joint has, in sections, a thickness which is less than a wall thickness of the metal plate and, in sections, a thickness which corresponds at least to the wall thickness of the metal plate. - at least two partial segments which are at least partially connected to one another and are each formed from a metal plate having a longitudinal extension and a widthwise extension, the longitudinal extension being greater than the width extension, and wherein - the partial segments each have longitudinal edges (8a, b) extending in the longitudinal extension and are joined to one another along the longitudinal edges (8a, b) by means of a welded joint in each case, - the partial segments each have end edges (10a, b) extending in widthwise extension, the partial segments each being bent along their end edges (10a, b), - the respective welded joint has, in sections, a thickness which is less than a wall thickness of the metal plate and, in sections, a thickness which corresponds at least to the wall thickness of the metal plate.
Learning aid for brass instruments for promoting a technically correct grip or wrist position, characterized by a receptacle for a leadpipe of a brass instrument, from which receptacle a thumb guide protrudes for positioning a thumb, wherein the thumb guide forms a stop for a thumb berry of the thumb and wherein a stop surface of the stop for the thumb tip extends at least in sections in a tilting surface which is tilted about a tilting axis from a reference surface which extends normal to the receptacle longitudinal axis..
A turbine component comprising: - a substrate of single-crystal nickel-based superalloy, comprising rhenium, having a γ-γ' Ni phase, and an average chromium mass fraction of less than 0.08; - a nickel-based metal superalloy sublayer covering the substrate, this sublayer comprising at least aluminum, nickel, chromium, silicon, hafnium; characterized in that: - the metal superalloy sublayer has a γ'-Ni 3 Al phase predominantly by volume - a substrate of single-crystal nickel-based superalloy, comprising rhenium, having a γ-γ' Ni phase, and an average chromium mass fraction of less than 0.08; - a nickel-based metal superalloy sublayer covering the substrate, this sublayer comprising at least aluminum, nickel, chromium, silicon, hafnium; - the metal superalloy sublayer has a γ'-Ni 3 Al phase predominantly by volume
An eyeglass frame comprising a lens retaining part having an end piece (150, 155) and a temple piece (110, 115), said end piece (150, 155) having an edge with a projection (510, 515), and a hinge (140, 145) connecting the end piece (150, 155) and the temple piece (110, 115), said hinge (140, 145) comprising: a substantially cylindrical element having a cylinder axis serving as a hinge axis and being integrally formed having a slot being aligned parallel to said cylinder axis of the substantially cylindrical element; said edge being adapted to be received in the slot (410, 710, 715) of the substantially cylindrical element with said projection (510, 515) in holes (420, 520) being positioned inside said slot (410, 710, 715) perpendicular to the hinge axis; and a substantially cylindrical support member (240, 250) coupled to the temple piece (110, 115), adapted to accept the substantially cylindrical element and comprising retaining means adapted to maintain the projection (510, 515) in the slot (410, 710, 715) of the substantially cylindrical element characterized in that said holes (420, 520) are aligned with said slot, said holes (420, 520) being aligned perpendicular to the cylinder axis of the substantially cylindrical element, the assembly means comprise recesses (430, 435) on the substantially cylindrical support member (240, 250), the recesses (430, 435) being adapted to accommodate passage of the projection through the substantially cylindrical support member (240, 250) when the recesses (430, 435) are aligned with the slot.
Container, formed and configured to receive and discharge portions of a product mass flow (20, 27) formed from rod-shaped articles of the tobacco-processing industry during the transport movement of the containers in transport direction T in an arrangement for discretising or forming a product mass flow (20, 27), comprising a base body formed from two side walls (11, 12), two end walls (13, 14) as well as a bottom wall which forms a receiving chamber for the portions, wherein the receiving chamber is dimensioned in terms of width transversely to transport direction T and in terms of height perpendicular to the bottom wall for receiving such portions which have the original structure and the original cross-section of the supplied product mass flow (20, 27) or the structure and the cross-section of the product mass flow (20, 27) to be formed, wherein both end walls (13, 14) are formed to be at least partially open for collision-free transport in the arrangement, characterized in that at least one of the two side walls (11, 12) is formed to be adjustable or positionable relative to the other side wall (11, 12) in order to change distance A between the side walls (11, 12).
A method for configuring a prosthesis and/or orthosis or for determining mal-positions in the mounting of a prosthesis and/or orthosis of the lower limb, wherein the method is conducted entirely by a computer or an electric data processing device, featuring the steps: a. Recording a first set of measurement data of at least one sensor that is fixed to a body part of a person, wherein the first set of measurement data is allocated to a first state of movement of the person, b. Recording a second set of measurement data of at least one sensor that is fixed to a body part of a person, wherein the second set of measurement data is allocated to a second state of movement of the person, wherein the two states of movement differ from one another c. Evaluating of the first and second set of measurement data, d. Detecting a corrective measure after evaluating the first and second set of measurement data, characterized in that the first and second set of measurement data are evaluated simultaneously. a. Recording a first set of measurement data of at least one sensor that is fixed to a body part of a person, wherein the first set of measurement data is allocated to a first state of movement of the person, b. Recording a second set of measurement data of at least one sensor that is fixed to a body part of a person, wherein the second set of measurement data is allocated to a second state of movement of the person, wherein the two states of movement differ from one another c. Evaluating of the first and second set of measurement data, d. Detecting a corrective measure after evaluating the first and second set of measurement data,
A two-part ball bearing cage for a ball bearing, comprising a first and a second annular body (1a, 1b) having, at the mutual facing end faces thereof, a plurality of holding claws, wherein the two annular bodies (1a, 1b) are formed identically and mountable on one another such that the holding claws of the one annular body (1a, 1b) are received in the recesses adjacent to the holding claws of the other annular body (1b, la), whereby, in the circumferential direction, a number of mutually spaced-apart pockets for receiving and guiding of the equal number of roller bodies are present, characterised in that, on both mutually facing end faces of the annular bodies (1a, 1b) in the circumferential direction, a pair of holding claws arranged radially adjacent thereto with a recess arranged between these two holding claws, a subsequent pocket base, and a single holding claw arranged at the end of the pocket base with two recesses arranged radially adjacent thereto each follow each other repeatedly so that, after the mounting of the ball bearing cage, each pocket is formed by at least two pairs of holding claws and at least two individual holding claws together with two pocket bases, wherein, between two pockets, in a circumferential spacing between a pair of holding claws of one pocket and a single holding claw of a neighbouring other pocket, there is formed a resulting free space, which is suitable for receiving lubricant, and wherein the pockets and the free spaces are fluidly interconnected via passages.
A strut for a gas turbine engine, the strut comprising: a strut passage extending through the strut along a radial length of the strut; a tube disposed within the strut passage and spaced from an interior surface of the strut passage; and a grommet disposed about the tube and in communication with the interior surface of the strut passage, characterized in that the grommet defines a compressible zone comprising a hollow space extending radially through the grommet, the compressible zone disposed between the tube and the interior surface of the strut passage, wherein the grommet comprises a first portion disposed about a perimeter of the tube and at least one second portion extending from the first portion away from the tube, an exterior surface of the first portion and an interior surface of the second portion defining the compressible zone therebetween and wherein an exterior surface of the second portion forms an interface with the interior surface of the strut passage, and wherein the second portion is in communication with the interior surface of the strut passage and the first portion is spaced from the interior surface of the strut passage. a strut passage extending through the strut along a radial length of the strut; a tube disposed within the strut passage and spaced from an interior surface of the strut passage; and a grommet disposed about the tube and in communication with the interior surface of the strut passage, characterized in that the grommet defines a compressible zone comprising a hollow space extending radially through the grommet, the compressible zone disposed between the tube and the interior surface of the strut passage, wherein the grommet comprises a first portion disposed about a perimeter of the tube and at least one second portion extending from the first portion away from the tube, an exterior surface of the first portion and an interior surface of the second portion defining the compressible zone therebetween and wherein an exterior surface of the second portion forms an interface with the interior surface of the strut passage, and wherein the second portion is in communication with the interior surface of the strut passage and the first portion is spaced from the interior surface of the strut passage.
A method of producing a polypeptide of interest in a glutamine-free cell culture media, comprising culturing mammalian cells expressing the polypeptide of interest in a cell culture medium under conditions that support expression of the polypeptide of interest, wherein said cell culture medium comprises between 20 μM and 1000 μM hypoxanthine and between 2 μM and 1000 μM thymidine.