A computer-implemented method for determining an estimate of radiation dose absorbed by a first individual in receiving an imaging scan, the method comprising: selecting an initial mathematical phantom for the first individual, the selecting being based on at least one of an age, a gender, a weight and a height of the first individual; segmenting a reference computerized tomography "CT" scan associated with the first individual to identify a three-dimensional "3D" volume of a plurality of anatomical landmarks of the first individual present in the reference CT scan; for at least one of the plurality of anatomical landmarks, determining a centroid of the respective 3D volume; matching one or more of the identified anatomical landmarks in the segmented reference CT scan to corresponding anatomical landmarks in the initial mathematical phantom; and deforming the initial mathematical phantom based on the matched anatomical landmarks whereby the deformed mathematical phantom resulting therefrom better matches a size, a shape and organ positions of the first individual; receiving a set of parameters describing the imaging scan and an image scanning apparatus being used to perform the imaging scan of the first individual; accessing a simulation library comprising a plurality of previously completed simulations estimating radiation dose absorption corresponding to one or more second individuals; evaluating the plurality of previously completed simulations estimating radiation dose absorption corresponding to the one or more second individuals; and upon determining, based on the evaluation, that two or more of the plurality of previously completed simulations in the simulation library have a set of parameters that match within a specified tolerance measure the received set of parameters and the deformed mathematical phantom, interpolating the estimates of radiation dose in the two or more previously completed simulations to determine the estimate of radiation dose absorbed by the first individual in receiving the imaging scan. selecting an initial mathematical phantom for the first individual, the selecting being based on at least one of an age, a gender, a weight and a height of the first individual; segmenting a reference computerized tomography "CT" scan associated with the first individual to identify a three-dimensional "3D" volume of a plurality of anatomical landmarks of the first individual present in the reference CT scan; for at least one of the plurality of anatomical landmarks, determining a centroid of the respective 3D volume; matching one or more of the identified anatomical landmarks in the segmented reference CT scan to corresponding anatomical landmarks in the initial mathematical phantom; and deforming the initial mathematical phantom based on the matched anatomical landmarks whereby the deformed mathematical phantom resulting therefrom better matches a size, a shape and organ positions of the first individual; receiving a set of parameters describing the imaging scan and an image scanning apparatus being used to perform the imaging scan of the first individual; accessing a simulation library comprising a plurality of previously completed simulations estimating radiation dose absorption corresponding to one or more second individuals; evaluating the plurality of previously completed simulations estimating radiation dose absorption corresponding to the one or more second individuals; and upon determining, based on the evaluation, that two or more of the plurality of previously completed simulations in the simulation library have a set of parameters that match within a specified tolerance measure the received set of parameters and the deformed mathematical phantom, interpolating the estimates of radiation dose in the two or more previously completed simulations to determine the estimate of radiation dose absorbed by the first individual in receiving the imaging scan.