mhurhangee/ep-ind-claims huggingface dataset:
An accommodating intraocular lens device configured to be implanted into an eye, said lens device comprising: a lens portion configured to be located in a reference plane (P R) oriented substantially perpendicular relative to a central focal axis of the eye when said lens device is implanted into the eye; characterised by a substantially flat plate haptic portion located in said reference plane (P R) and having a through-hole in which the lens portion is disposed such that the plate haptic portion surrounds and is separated from said lens portion, said plate haptic portion configured to bow with respect to said reference plane (P R) when force is applied by the eye inwardly on opposite edges of said plate haptic portion and unbow when force is released on said opposite edges of said plate haptic portion so that a centre of said plate haptic portion moves in and out of said reference plane (P R); and a connection portion defined by said through-hole and configured to connect said lens portion to said plate haptic portion, said connection portion configured to move said lens portion in and out of said reference plane (P R) in a manner to focus the eye when force is applied by the eye inwardly to said opposite edges of said plate haptic portion causing said plate haptic portion to bow. a lens portion configured to be located in a reference plane (P R) oriented substantially perpendicular relative to a central focal axis of the eye when said lens device is implanted into the eye; characterised by a substantially flat plate haptic portion located in said reference plane (P R) and having a through-hole in which the lens portion is disposed such that the plate haptic portion surrounds and is separated from said lens portion, said plate haptic portion configured to bow with respect to said reference plane (P R) when force is applied by the eye inwardly on opposite edges of said plate haptic portion and unbow when force is released on said opposite edges of said plate haptic portion so that a centre of said plate haptic portion moves in and out of said reference plane (P R); and a connection portion defined by said through-hole and configured to connect said lens portion to said plate haptic portion, said connection portion configured to move said lens portion in and out of said reference plane (P R) in a manner to focus the eye when force is applied by the eye inwardly to said opposite edges of said plate haptic portion causing said plate haptic portion to bow.
A filtering apparatus of a multimode multiband radio transceiver, the apparatus comprising: a first filtering unit configured to filter baseband signals on one of at least one frequency bands, the first filtering unit comprising a plurality of filter blocks (332, 334, 336, 338; 1006, 1008, 1012, 1014), the plurality of filter blocks comprising a first filter block (334; 1008) and a second filter block (332; 1006), each of the first filter block and the second filter block comprising a capacitor; a switching unit (330; 1040; 1050; 1060) configured to switch the baseband signals to the plurality of filter blocks according to a selected communication mode; and a control unit configured to select the communication mode and to control the switching unit, wherein the capacitor of the second filter block is configured to be connectable to the capacitor of the first filter block, depending on the selected communication mode. a first filtering unit configured to filter baseband signals on one of at least one frequency bands, the first filtering unit comprising a plurality of filter blocks (332, 334, 336, 338; 1006, 1008, 1012, 1014), the plurality of filter blocks comprising a first filter block (334; 1008) and a second filter block (332; 1006), each of the first filter block and the second filter block comprising a capacitor; a switching unit (330; 1040; 1050; 1060) configured to switch the baseband signals to the plurality of filter blocks according to a selected communication mode; and a control unit configured to select the communication mode and to control the switching unit, wherein the capacitor of the second filter block is configured to be connectable to the capacitor of the first filter block, depending on the selected communication mode.
Vulcanizable composition comprising (i) at least one optionally fully or partly hydrogenated nitrile rubber containing epoxy groups and comprising repeat units derived from at least one conjugated diene, at least one α,β-unsaturated nitrile and optionally one or more further copolymerizable monomers, but not from a nonconjugated cyclic polyene, (ii) at least one Lewis and/or Brønsted base as a crosslinker, (iii)at least one crosslinking accelerator selected from the group consisting of thiurams, xanthogenates, dithiocarbamates and carbamates, where the Lewis and/or Brønsted base (ii) must be different from the defined group of crosslinking accelerators (iii), and also crosslinkers other than those mentioned in (ii) are present in the vulcanizable composition only in an amount of less than 2.5 parts by weight based on 100 parts by weight of the optionally fully or partly hydrogenated nitrile rubber (i) containing epoxy groups, and crosslinking accelerators other than those mentioned in (iii) are present only in an amount of less than 2.5 parts by weight based on 100 parts by weight of the optionally fully or partly hydrogenated nitrile rubber (i) containing epoxy groups. (i) at least one optionally fully or partly hydrogenated nitrile rubber containing epoxy groups and comprising repeat units derived from at least one conjugated diene, at least one α,β-unsaturated nitrile and optionally one or more further copolymerizable monomers, but not from a nonconjugated cyclic polyene, (ii) at least one Lewis and/or Brønsted base as a crosslinker, (iii)at least one crosslinking accelerator selected from the group consisting of thiurams, xanthogenates, dithiocarbamates and carbamates,
A producing method of a grain-oriented electrical steel sheet, the method comprising: forming a preferentially-deformable portion in one end region of a steel sheet over an entire length of the steel sheet or at a part of the steel sheet in the rolling direction thereof so as to be parallel with the rolling direction of the steel sheet; coiling the steel sheet; and performing a final annealing to the steel sheet after disposing the steel sheet in a manner such that the end region becomes a lower side of the steel sheet, wherein the preferentially-deformable portion is a grain boundary sliding portion, and the grain boundary sliding portion after the final annealing is one linear crystal grain boundary or a sliding band which includes crystal grains and has a width of from 0.02 to 20 mm; wherein the preferentially-deformable portion is formed by irradiation of a laser beam, in which energy density Ed is controlled to satisfy Equation, the Ed being expressed by Equation using a laser power P, a diameter de (mm) in a sheet width direction(C direction) of the laser beam, and a feeding speed VL (mm/s) of the steel sheet, Ed = 4 / π × P / dc × VL 0.5 J / mm 2 ≤ Ed ≤ 5.0 J / mm 2 forming a preferentially-deformable portion in one end region of a steel sheet over an entire length of the steel sheet or at a part of the steel sheet in the rolling direction thereof so as to be parallel with the rolling direction of the steel sheet; coiling the steel sheet; and performing a final annealing to the steel sheet after disposing the steel sheet in a manner such that the end region becomes a lower side of the steel sheet, wherein the preferentially-deformable portion is a grain boundary sliding portion, and the grain boundary sliding portion after the final annealing is one linear crystal grain boundary or a sliding band which includes crystal grains and has a width of from 0.02 to 20 mm; wherein the preferentially-deformable portion is formed by irradiation of a laser beam, in which energy density Ed is controlled to satisfy Equation, the Ed being expressed by Equation using a laser power P, a diameter de (mm) in a sheet width direction(C direction) of the laser beam, and a feeding speed VL (mm/s) of the steel sheet, Ed = 4 / π × P / dc × VL 0.5 J / mm 2 ≤ Ed ≤ 5.0 J / mm 2
A confocal measurement device using confocal optics to measure a profile of a measurement target, the confocal measurement device comprising: a light source for emitting polychromatic light; a diffraction lens for chromatically distorting the light emitted from the light source along the direction of an optical axis; a measurement unit (23, 24) for measuring the intensity at each wavelength of the light within the chromatically distorted light created by the diffraction lens and focused on the measurement target; and an optical fiber serving as an optical path from the diffraction lens to the light source and to the measurement unit (23, 24); wherein the end of the optical fiber is inclined relative to the optical axis of the diffraction lens, so that the primary light ray from the light source to the diffraction lens is inclined relative to the optical axis of the diffraction lens. a light source for emitting polychromatic light; a diffraction lens for chromatically distorting the light emitted from the light source along the direction of an optical axis; a measurement unit (23, 24) for measuring the intensity at each wavelength of the light within the chromatically distorted light created by the diffraction lens and focused on the measurement target; and an optical fiber serving as an optical path from the diffraction lens to the light source and to the measurement unit (23, 24); wherein the end of the optical fiber is inclined relative to the optical axis of the diffraction lens, so that the primary light ray from the light source to the diffraction lens is inclined relative to the optical axis of the diffraction lens.
A method for targeting a desired depth to deliver content to an upper skin surface, comprising the steps of: placing an infusion set having a moveable first hub (2, 28, 260) on an infusion site, wherein said first hub (2, 28, 260) comprises a needle (5, 26, 280); sliding a cover (12, 120), of said infusion set parallel to a skin surface to move said first hub (2, 28, 260) and place said needle (5, 26, 280) into said skin surface, removing said cover (12, 120) from said infusion set and attaching an infusion pump tube attachment, and attaching said infusion pump tube attachment to said first hub via a tube segment and a tortuous path adhesive segment, wherein said tube segment and tortuous path adhesive segment are configured to isolate said first hub from movement. placing an infusion set having a moveable first hub (2, 28, 260) on an infusion site, wherein said first hub (2, 28, 260) comprises a needle (5, 26, 280); sliding a cover (12, 120), of said infusion set parallel to a skin surface to move said first hub (2, 28, 260) and place said needle (5, 26, 280) into said skin surface, removing said cover (12, 120) from said infusion set and attaching an infusion pump tube attachment, and attaching said infusion pump tube attachment to said first hub via a tube segment and a tortuous path adhesive segment, wherein said tube segment and tortuous path adhesive segment are configured to isolate said first hub from movement.
Recharging device for electrical equipment, in particular for an electric vehicle, the recharging device being intended to be connected to a supply network delivering at least one alternating input voltage (Ve(t)) to the recharging device, the recharging device being configured to supply the electrical equipment with at least one continuous output voltage (Vs(t)), the recharging device comprising: - an input terminal intended to be connected to the supply network; - an output terminal intended to be connected to the electrical equipment; - a filter module comprising a filter input terminal (Ef) connected to the input terminal of the recharging device, and a filter output terminal (Sf), the filter module being configured to provide a filter output voltage (Vsf(t)) via the filter output terminal (Sf), characterized in that the recharging device further comprises a feedback module coupled to the filter module and comprising a feedback input terminal (Er) connected to the filter output terminal (Sf) and a feedback output terminal (Sr) connected to the filter input terminal (Ef), the feedback module being configured to generate a feedback voltage (Vsr(t)) from the filter output voltage (Vsf(t)) and for outputting the feedback voltage via the feedback output terminal (Sr) in order to compensate for disturbances in the input voltage (Ve(t)) resulting from a non-linear behavior of the recharging device, said feedback voltage (Vsr(t)) being in opposition with the input voltage (Ve(t)) of the recharging device, opposition meaning that, at an instant when the input voltage Ve(t) is at a local maximum, the feedback voltage is at a local minimum, and vice versa with a local minimum of the input voltage and a local maximum of the feedback voltage. - an input terminal intended to be connected to the supply network; - an output terminal intended to be connected to the electrical equipment; - a filter module comprising a filter input terminal (Ef) connected to the input terminal of the recharging device, and a filter output terminal (Sf), the filter module being configured to provide a filter output voltage (Vsf(t)) via the filter output terminal (Sf),
A lubricant comprising: a multidentate lubricant comprising an anchoring moiety R a attached to a plurality of sidechain moieties -(R b -R e) according to a general formula: R a -(R b -R e) x; wherein R a is a multivalent radical of valence x; wherein each R b is, independently, a divalent moiety comprising the general formula: -OCH 2 CF 2 -O-(CF 2 CF 2 O) b -C(R #) 2 CH 2 -; wherein each R # is a hydrogen atom; wherein each b is, independently, from 1 to 10; wherein x is greater than or equal to 2; and wherein each R e is a hydroxyl (-OH) group. wherein R a is a multivalent radical of valence x; wherein each R b is, independently, a divalent moiety comprising the general formula: -OCH 2 CF 2 -O-(CF 2 CF 2 O) b -C(R #) 2 CH 2 -; wherein each R # is a hydrogen atom; wherein each b is, independently, from 1 to 10; wherein x is greater than or equal to 2; and wherein each R e is a hydroxyl (-OH) group.
Method for preparation of a skin substitute comprising the following steps: a. fibroblasts culture in a fibroblast culture medium M1; b. seeding of a matrix comprising collagen with fibroblasts obtained from step a; c. culture of seeded fibroblasts in a matrix comprising collagen in a fibroblasts culture medium M2, the matrix and the cultivated fibroblasts forming a dermis substitute; d. melanocytes culture in a melanocytes culture medium M3; e. keratinocytes culture in a keratinocytes culture medium M4; f. mix of melanocytes obtained in step d with keratinocytes obtained in step e; g. seeding of the dermis substitute obtained in step c with the mix obtained in step f; h. dermis substitute culture seeded in step g in a skin culture medium M5 thus forming the skin substitute. wherein the medium M2 comprises ascorbic acid or an ascorbate, the medium M5 comprises hyaluronic acid or a hyaluronate or a derivative of these products, and seeding in step g is done with a (keratinocytes + melanocytes)/fibroblasts ratio from 9 and 19. a. fibroblasts culture in a fibroblast culture medium M1; b. seeding of a matrix comprising collagen with fibroblasts obtained from step a; c. culture of seeded fibroblasts in a matrix comprising collagen in a fibroblasts culture medium M2, the matrix and the cultivated fibroblasts forming a dermis substitute; d. melanocytes culture in a melanocytes culture medium M3; e. keratinocytes culture in a keratinocytes culture medium M4; f. mix of melanocytes obtained in step d with keratinocytes obtained in step e; g. seeding of the dermis substitute obtained in step c with the mix obtained in step f; h. dermis substitute culture seeded in step g in a skin culture medium M5 thus forming the skin substitute.
A method, comprising: providing a microfluidic system (200, 700) comprising a first microfluidic channel (230, 730, 750, 310, 910, 600, 800) and a second microfluidic channel (240, 740, 760, 330, 920, 610, 810) contacting the first microfluidic channel at an intersection (260, 750, 765); providing a first fluid in the first microfluidic channel and a second fluid in the second microfluidic channel, wherein the first fluid and the second fluid contact each other at least partially within the intersection to define a fluidic interface (350, 930, 620, 840); and urging the second fluid to enter the first microfluidic channel, characterized in that when an electric field is applied to the interface, the second fluid is prevented from entering the first microfluidic channel. providing a microfluidic system (200, 700) comprising a first microfluidic channel (230, 730, 750, 310, 910, 600, 800) and a second microfluidic channel (240, 740, 760, 330, 920, 610, 810) contacting the first microfluidic channel at an intersection (260, 750, 765); providing a first fluid in the first microfluidic channel and a second fluid in the second microfluidic channel, wherein the first fluid and the second fluid contact each other at least partially within the intersection to define a fluidic interface (350, 930, 620, 840); and urging the second fluid to enter the first microfluidic channel, characterized in that when an electric field is applied to the interface, the second fluid is prevented from entering the first microfluidic channel.
A ciphertext comparison method using homomorphic encryption, the method being performed in a computing apparatus including one or more processors and a memory for storing one or more programs executable by the one or more processors; the ciphertext comparison method comprising: acquiring a first ciphertext obtained by encrypting first real-number data using a homomorphic encryption algorithm and a second ciphertext obtained by encrypting second real-number data using the homomorphic encryption algorithm; and generating a ciphertext for a result for comparison in size between the first real-number data and the second real-number data using homomorphic evaluation of the first ciphertext, the second ciphertext, and an approximation function for approximating a signum function. acquiring a first ciphertext obtained by encrypting first real-number data using a homomorphic encryption algorithm and a second ciphertext obtained by encrypting second real-number data using the homomorphic encryption algorithm; and generating a ciphertext for a result for comparison in size between the first real-number data and the second real-number data using homomorphic evaluation of the first ciphertext, the second ciphertext, and an approximation function for approximating a signum function.
A method of controlling operation of a high-temperature storage battery connected to an electric power system, comprising the steps of, when the temperature of the storage battery is equal to or lower than a reference temperature (Ta), charging and discharging the storage battery with charging and discharging electric power, which is the sum of charging and discharging electric power based on a preset process of operating the storage battery and additional charging and discharging electric power corresponding to charging and discharging cycles each of a continuous charging time of 1 hour or shorter and a continuous discharging time of 1 hour or shorter, for thereby supplying thermal energy to the storage battery, characterized in that for rising battery temperature up to a target temperature (Tc), which is lower than the reference temperature (Ta), an electrical heater is applied, and for rising battery temperature above the target temperature (Tc) priority is given to supply thermal energy to the storage battery by the additional charging and discharging of electric power, over supply of thermal energy to the storage battery by the electrical heater, wherein the amount of thermal energy supplied to the storage battery by the additional charging and discharging is controlled by setting the average amplitude of the additional charging and discharging.
An electrode structure comprising a substrate and a sintered body, wherein the sintered body is formed on the surface of the substrate, wherein the sintered body is provided with cracks that are formed by rolling with a round rod after a hydration treatment of the sintered body and before a formation process of the sintered body, and the cracks penetrate both ends of the electrode structure.
A computer-implemented method for identifying responsiveness to therapy for a subject suffering from cancer, the method comprising: receiving data associated with a cancerous lesion in the subject; processing the data to determine values for biomarkers in the cancerous lesion; wherein the biomarkers comprise: (i) an expression level of three prime repair exonuclease 1 (TREX1) in the cancerous lesion; (ii) an expression level of programmed death-ligand 1 (PD-L1) on tumor cells in the cancerous lesion; and (iii) a level of infiltration of immune cells in the cancerous lesion; processing the determined values of the biomarkers by comparing them to a control value to obtain a score indicative of responsiveness of the cancerous lesion to each of a plurality of treatment modalities; wherein the treatment modalities comprise a defined radiation dose and/or fractionation in combination with immunotherapy; ranking the treatment modalities based on the obtained responsiveness scores in order to indicate a treatment modality that is likely to be most effective in treating the cancerous lesion in the subject; providing output comprising the ranking for the treatment modalities to a user on a display for decision support for choosing the treatment modality for the cancerous lesion. receiving data associated with a cancerous lesion in the subject; processing the data to determine values for biomarkers in the cancerous lesion; wherein the biomarkers comprise: (i) an expression level of three prime repair exonuclease 1 (TREX1) in the cancerous lesion; (ii) an expression level of programmed death-ligand 1 (PD-L1) on tumor cells in the cancerous lesion; and (iii) a level of infiltration of immune cells in the cancerous lesion; (i) an expression level of three prime repair exonuclease 1 (TREX1) in the cancerous lesion; (ii) an expression level of programmed death-ligand 1 (PD-L1) on tumor cells in the cancerous lesion; and (iii) a level of infiltration of immune cells in the cancerous lesion; processing the determined values of the biomarkers by comparing them to a control value to obtain a score indicative of responsiveness of the cancerous lesion to each of a plurality of treatment modalities; wherein the treatment modalities comprise a defined radiation dose and/or fractionation in combination with immunotherapy; ranking the treatment modalities based on the obtained responsiveness scores in order to indicate a treatment modality that is likely to be most effective in treating the cancerous lesion in the subject; providing output comprising the ranking for the treatment modalities to a user on a display for decision support for choosing the treatment modality for the cancerous lesion.