A compound of Formula: or a pharmaceutically acceptable salt thereof, wherein: Ring A is: i) of Formula (A-i): ii) of Formula (A-ii): iii) of Formula (A-iii): or iv) of Formula (A-v): R A1 is selected from the group consisting of hydrogen, alkyl, aryl, and a nitrogen protecting group; each instance of R A2 is independently selected from the group consisting of hydrogen, alkyl, aryl, and -OR A2a, wherein each occurrence of R A2a is independently selected from the group consisting of hydrogen, acyl, alkyl, and an oxygen protecting group; each instance of R a is independently hydrogen, acyl, alkyl, or a nitrogen protecting group; k is 0, 1, 2, 3, 4, 5, or 6; L 1 is a bond, -O-, or -NR c-; each instance of R b is independently hydrogen, halogen, or C 1-6 alkyl; each instance of R c is independently hydrogen, C 1-6 alkyl, or a nitrogen protecting group; R B1 is hydrogen or -N(R a) 2; R B2 is hydrogen, halogen, or substituted or unsubstituted alkyl; X is -NR c -; Ring C is a phenyl ring; Ring D is a phenyl ring, monocyclic carbocyclic ring, or monocyclic heterocyclic ring; each instance of R c is independently halogen or alkyl; n is 0, 1, 2, 3, or 4; L 2 is -NR c C(=O)-, -C(R b) 2 -, -C(=O)-, -C(R b) 2 C(=O)-, -C(=O)NR c -, - C(R b) 2 C(=O)NR c -, or a substituted or unsubstituted C 1-4 hydrocarbon chain, optionally wherein one or more carbon units of the hydrocarbon chain are independently replaced with -C(=O)-, - O-, -S-, -S(=O)-, -S(=O)2-, or -NR c -; each instance of R D is independently halogen or alkyl; p is 0 or 1; R E is of the formula: L 3 is -NR c C(=O)-; each of R E1 and R E2 is hydrogen; and R E3 is -CH 2 N(CH 3) 2. Ring A is: i) of Formula (A-i): ii) of Formula (A-ii): iii) of Formula (A-iii): or iv) of Formula (A-v): i) of Formula (A-i): ii) of Formula (A-ii): iii) of Formula (A-iii): or iv) of Formula (A-v): R A1 is selected from the group consisting of hydrogen, alkyl, aryl, and a nitrogen protecting group; each instance of R A2 is independently selected from the group consisting of hydrogen, alkyl, aryl, and -OR A2a, wherein each occurrence of R A2a is independently selected from the group consisting of hydrogen, acyl, alkyl, and an oxygen protecting group; each instance of R a is independently hydrogen, acyl, alkyl, or a nitrogen protecting group; k is 0, 1, 2, 3, 4, 5, or 6; L 1 is a bond, -O-, or -NR c-; each instance of R b is independently hydrogen, halogen, or C 1-6 alkyl; each instance of R c is independently hydrogen, C 1-6 alkyl, or a nitrogen protecting group; R B1 is hydrogen or -N(R a) 2; R B2 is hydrogen, halogen, or substituted or unsubstituted alkyl; X is -NR c -; Ring C is a phenyl ring; Ring D is a phenyl ring, monocyclic carbocyclic ring, or monocyclic heterocyclic ring; each instance of R c is independently halogen or alkyl; n is 0, 1, 2, 3, or 4; L 2 is -NR c C(=O)-, -C(R b) 2 -, -C(=O)-, -C(R b) 2 C(=O)-, -C(=O)NR c -, - C(R b) 2 C(=O)NR c -, or a substituted or unsubstituted C 1-4 hydrocarbon chain, optionally wherein one or more carbon units of the hydrocarbon chain are independently replaced with -C(=O)-, - O-, -S-, -S(=O)-, -S(=O)2-, or -NR c -; each instance of R D is independently halogen or alkyl; p is 0 or 1; R E is of the formula: L 3 is -NR c C(=O)-; each of R E1 and R E2 is hydrogen; and R E3 is -CH 2 N(CH 3) 2.