Compounds according to general formula in which formula R 1 represents a hydrogen atom, lower alkyl group, which is a branched or unbranched alkyl group with 1-4 carbon atoms, lower alkenyl group, which is a branched or unbranched alkenyl group with 2-4 carbon atoms, aryl group, aralkyl group, or heterocyclic group, wherein the above aryl, aralkyl and heterocyclic groups are optionally substituted in ortho, meta and/or para position with 1, 2, 3 or 4 electron withdrawing groups selected from halogen atoms, trifluoromethyl or nitro groups, or electron donating groups selected from lower alkyl groups, which are branched or unbranched alkyl groups with 1-4 carbon atoms; R 2 represents a hydrogen atom, lower alkyl group, which is a branched or unbranched alkyl group with 1-4 carbon atoms, aryl group, aralkyl group, or heterocyclic group, wherein the above groups are optionally substituted with one or more halogen atoms; R 3 represents an aryl group, aralkyl group, or heterocyclic group, wherein the above groups are optionally substituted in ortho, meta or para position with 1, 2, 3 or 4 electron withdrawing groups selected from halogen atoms, trifluoromethyl or nitro groups, or electron donating groups selected from lower alkyl groups, which are branched or unbranched alkyl groups with 1-4 carbon atoms; R 4 represents a hydrogen atom, lower alkyl group, which is a branched or unbranched alkyl group with 1-4 carbon atoms, or an acidic functional group selected from methoxycarbonyl group, nitrile or acid amide group; n is 1 or 2; and their pharmaceutically acceptable salt for use in a method for the prophylaxis or treatment of ischemia, reperfusion injury, cardiovascular disorders, neurodegenerative disorders (including especially Alzheimer's disease and Huntington's disease), trauma, neuropsychiatric diseases (including especially depression and anxiety disorders), and liver, kidney and lung injuries. R 1 represents a hydrogen atom, lower alkyl group, which is a branched or unbranched alkyl group with 1-4 carbon atoms, lower alkenyl group, which is a branched or unbranched alkenyl group with 2-4 carbon atoms, aryl group, aralkyl group, or heterocyclic group, wherein the above aryl, aralkyl and heterocyclic groups are optionally substituted in ortho, meta and/or para position with 1, 2, 3 or 4 electron withdrawing groups selected from halogen atoms, trifluoromethyl or nitro groups, or electron donating groups selected from lower alkyl groups, which are branched or unbranched alkyl groups with 1-4 carbon atoms; R 2 represents a hydrogen atom, lower alkyl group, which is a branched or unbranched alkyl group with 1-4 carbon atoms, aryl group, aralkyl group, or heterocyclic group, wherein the above groups are optionally substituted with one or more halogen atoms; R 3 represents an aryl group, aralkyl group, or heterocyclic group, wherein the above groups are optionally substituted in ortho, meta or para position with 1, 2, 3 or 4 electron withdrawing groups selected from halogen atoms, trifluoromethyl or nitro groups, or electron donating groups selected from lower alkyl groups, which are branched or unbranched alkyl groups with 1-4 carbon atoms; R 4 represents a hydrogen atom, lower alkyl group, which is a branched or unbranched alkyl group with 1-4 carbon atoms, or an acidic functional group selected from methoxycarbonyl group, nitrile or acid amide group; n is 1 or 2; and their pharmaceutically acceptable salt for use in a method for the prophylaxis or treatment of ischemia, reperfusion injury, cardiovascular disorders, neurodegenerative disorders (including especially Alzheimer's disease and Huntington's disease), trauma, neuropsychiatric diseases (including especially depression and anxiety disorders), and liver, kidney and lung injuries.