mhurhangee/ep-ind-claims huggingface dataset:
Method for reprogramming living cells in which a cocktail comprising at least three transcription factors is transfected into the interior of at least one cell in order to convert this cell into an iPS cell or another type of cell, comprising the following steps: - providing a cocktail without viral carrier with at least three transcription factors commonly used for direct reprogramming in an aqueous environment of the at least one cell to be reprogrammed, - providing a radiation source in the form of a femtosecond laser with a pulse repetition frequency ranging between 50 MHz and 2 GHz with a wavelength ranging from 700 to 1200 nm, - directing a laser beam of the femtosecond laser by means of a laser-scanning microscope with a numerical aperture of between 0.9 and 1.5 on a cell membrane of the cell to be programmed in a focus in a sample with the at least one cell on a displaceable x-y table, - directing an attenuated, non-destructive laser beam of the femtosecond laser, which is also used for optical treatment, for establishing and observing the at least one selected cell in the focus of the laser-scanning microscope by means of a scanner, and - controlling the position of the at least one cell with respect to the focus, the exposure period and laser output for the optical treatment such that the focus depending on the pulse repetition frequency with an output between 7 and 100 mW generates a transient small-pore opening with a size in the range of up to 500 nm within a cell membrane of the cell in order to allow a diffusion of the cocktail for multiple reprogramming of the cell through the cell membrane into the interior of the cell such that a virus-free optical multiple reprogramming takes place. - providing a cocktail without viral carrier with at least three transcription factors commonly used for direct reprogramming in an aqueous environment of the at least one cell to be reprogrammed, - providing a radiation source in the form of a femtosecond laser with a pulse repetition frequency ranging between 50 MHz and 2 GHz with a wavelength ranging from 700 to 1200 nm, - directing a laser beam of the femtosecond laser by means of a laser-scanning microscope with a numerical aperture of between 0.9 and 1.5 on a cell membrane of the cell to be programmed in a focus in a sample with the at least one cell on a displaceable x-y table, - directing an attenuated, non-destructive laser beam of the femtosecond laser, which is also used for optical treatment, for establishing and observing the at least one selected cell in the focus of the laser-scanning microscope by means of a scanner, and - controlling the position of the at least one cell with respect to the focus, the exposure period and laser output for the optical treatment such that the focus depending on the pulse repetition frequency with an output between 7 and 100 mW generates a transient small-pore opening with a size in the range of up to 500 nm within a cell membrane of the cell in order to allow a diffusion of the cocktail for multiple reprogramming of the cell through the cell membrane into the interior of the cell such that a virus-free optical multiple reprogramming takes place.
A contamination information estimation system comprising: a communication terminal; a communication unit; an imaging unit configured to capture an image of a drain pan in a casing of an air treatment device; and a calculator including an estimator including an estimation model being a multilevel neural network in which a classification capability is acquired by machine learning and configured to estimate contamination information related to contamination on the drain pan based on image data captured by the imaging unit and operation data of the air treatment device and/or environment data related to an environment in which the air treatment device is provided, the communication unit being configured to transmit the image data, the operation data and the environment data via a network to the calculator, and wherein the calculator is configured to transmit contamination information to the communication terminal via the network. a communication terminal; a communication unit; an imaging unit configured to capture an image of a drain pan in a casing of an air treatment device; and a calculator including an estimator including an estimation model being a multilevel neural network in which a classification capability is acquired by machine learning and configured to estimate contamination information related to contamination on the drain pan based on image data captured by the imaging unit and operation data of the air treatment device and/or environment data related to an environment in which the air treatment device is provided, the communication unit being configured to transmit the image data, the operation data and the environment data via a network to the calculator, and wherein the calculator is configured to transmit contamination information to the communication terminal via the network.
An optical film comprising: an acryl-based film; and a functional coating layer formed on at least one surface of the acryl-based film, containing a conductive material and a water-dispersible resin, and having surface resistance of 10 9 Q / sq to 10 13 Ω / sq wherein the water-dispersible resin is a water-dispersible polyurethane-based resin, and a weight average molecular weight of the polyurethane-based resin is 10,000 to 100,000, wherein the conductive material is a conductive polymer, wherein the functional coating layer includes the conductive polymer in 1 to 10 parts by weight with respect to 100 parts by weight of the water-dispersible resin. an acryl-based film; and a functional coating layer formed on at least one surface of the acryl-based film, containing a conductive material and a water-dispersible resin, and having surface resistance of 10 9 Q / sq to 10 13 Ω / sq wherein the water-dispersible resin is a water-dispersible polyurethane-based resin, and a weight average molecular weight of the polyurethane-based resin is 10,000 to 100,000, wherein the conductive material is a conductive polymer, wherein the functional coating layer includes the conductive polymer in 1 to 10 parts by weight with respect to 100 parts by weight of the water-dispersible resin.
A method of operation of a unified messaging system, UMS, (13, 73) comprising the UMS (13, 73): receiving a request to listen to a message stored in the UMS (13, 73), the request coming from a telephone device (16, 17, 20, 21, 22, 61) of a user connected to the UMS (13, 73) via a voice communication channel over a network (11, 15, 19, 71), the message having a security attribute comprising a voice channel security level, VCSL, set to a level corresponding to at least a level indicating encryption or a level indicating no encryption, respectively; negotiating with the telephone device (16, 17, 20, 21, 22, 61) of the user to encrypt the voice communication channel when the level of the VCSL indicates encryption in the event that the voice communication channel (11, 15, 19, 71) is unsecured, and encrypting the voice communication channel used by the user to listen to the message when the selectable security level is set to the level indicating encryption and the negotiating is successful; playing or transmitting the message to the user only if the voice communication channel is encrypted; otherwise, denying playout or transmission of the message over the voice communication channel. receiving a request to listen to a message stored in the UMS (13, 73), the request coming from a telephone device (16, 17, 20, 21, 22, 61) of a user connected to the UMS (13, 73) via a voice communication channel over a network (11, 15, 19, 71), the message having a security attribute comprising a voice channel security level, VCSL, set to a level corresponding to at least a level indicating encryption or a level indicating no encryption, respectively; negotiating with the telephone device (16, 17, 20, 21, 22, 61) of the user to encrypt the voice communication channel when the level of the VCSL indicates encryption in the event that the voice communication channel (11, 15, 19, 71) is unsecured, and encrypting the voice communication channel used by the user to listen to the message when the selectable security level is set to the level indicating encryption and the negotiating is successful; playing or transmitting the message to the user only if the voice communication channel is encrypted; otherwise, denying playout or transmission of the message over the voice communication channel.
A bracket for connecting a shelf to an upright having a plurality of regularly spaced apart slots, the bracket being capable of being attached to the upright at two positions of differing heights and comprising: an upper edge comprising shelf supporting means, at least one first hooked attachment means which co-operatively engages the lower edge of a slot when the bracket is in the lower of the two positions, at least one second hooked attachment means which co-operatively engages the upper edge of a slot when the bracket is in the higher of the two positions, and at least one supporting means which supportively engages the lower edge of a slot when the bracket is in the higher of the two positions; such that the upper edge of the bracket is held at substantially the same angle with respect to the upright when the bracket is in the higher or the lower of the two positions; at least one attachment lug defining the at least one first hooked attachment means and the at least one second hooked attachment means; characterised in that: an upper edge of the at least one first hooked attachment means is vertically positioned above a lower edge of a corresponding said at least one second hooked attachment means. an upper edge comprising shelf supporting means, at least one first hooked attachment means which co-operatively engages the lower edge of a slot when the bracket is in the lower of the two positions, at least one second hooked attachment means which co-operatively engages the upper edge of a slot when the bracket is in the higher of the two positions, and at least one supporting means which supportively engages the lower edge of a slot when the bracket is in the higher of the two positions; such that the upper edge of the bracket is held at substantially the same angle with respect to the upright when the bracket is in the higher or the lower of the two positions; at least one attachment lug defining the at least one first hooked attachment means and the at least one second hooked attachment means; an upper edge of the at least one first hooked attachment means is vertically positioned above a lower edge of a corresponding said at least one second hooked attachment means.
A nuclear radiation measurement apparatus (10B; 10C; 10D) comprising: a visible image acquisition unit that is configured to pick up a visible image; a radiation intensity acquisition unit that is configured to measure intensity distributions of nuclear radiation coming from a direction being substantially equal to an image picking up direction of the visible image acquisition unit; an intensity display unit that is configured to display an image obtained by overlaying an intensity distribution of radiation, which is represented by using a plurality of colors being allocated to the intensity distribution of radiation on the visible image, characterized in that the radiation measurement apparatus (10B; 10C; 10D) further comprises a movement distance calculation unit that is configured to calculate a movement distance between the visible images successively picked up by the visible image acquisition unit, the visible images having a higher space resolution than the radiation intensity distributions, and a resolution improvement unit that is configured to obtain a higher resolution intensity distribution of the radiation intensity distribution by using the movement distance calculated by the movement distance calculation unit and thereby overlaying one of two of the acquired radiation intensity distributions, which are acquired nearly simultaneously with the visual images, on the other, and wherein one radiation intensity distribution is shifted by a unit smaller than one cell of the radiation intensity distributions. a visible image acquisition unit that is configured to pick up a visible image; a radiation intensity acquisition unit that is configured to measure intensity distributions of nuclear radiation coming from a direction being substantially equal to an image picking up direction of the visible image acquisition unit; an intensity display unit that is configured to display an image obtained by overlaying an intensity distribution of radiation, which is represented by using a plurality of colors being allocated to the intensity distribution of radiation on the visible image, characterized in that the radiation measurement apparatus (10B; 10C; 10D) further comprises a movement distance calculation unit that is configured to calculate a movement distance between the visible images successively picked up by the visible image acquisition unit, the visible images having a higher space resolution than the radiation intensity distributions, and a resolution improvement unit that is configured to obtain a higher resolution intensity distribution of the radiation intensity distribution by using the movement distance calculated by the movement distance calculation unit and thereby overlaying one of two of the acquired radiation intensity distributions, which are acquired nearly simultaneously with the visual images, on the other, and wherein one radiation intensity distribution is shifted by a unit smaller than one cell of the radiation intensity distributions.
A closing insert (301, 701, 1001) configured to be inserted into a funnel (201, 202, 901) comprised by an associated urinal for urine collection, where the funnel has a receiving end for receiving urine and a termination end with an opening for passage of the urine into a container comprised by the urinal, where the closing insert comprises - a funnel-shaped passageway with a receiving end for receiving urine and a termination end with an opening for passage for the urine, - a positioning mechanism (304, 1004) defining at least first and second positions of the closing insert relative to the funnel, where the positioning mechanism enables displacement of the closing insert relative to the funnel along a longitudinal direction of the closing insert or the funnel between the first and second positions, where a part of the closing insert is configured to close the opening of the funnel when the positioning mechanism is in the first position, and to enable passage of the urine into the container when the positioning mechanism is in the second position. - a funnel-shaped passageway with a receiving end for receiving urine and a termination end with an opening for passage for the urine, - a positioning mechanism (304, 1004) defining at least first and second positions of the closing insert relative to the funnel, where the positioning mechanism enables displacement of the closing insert relative to the funnel along a longitudinal direction of the closing insert or the funnel between the first and second positions,
A compound represented by formula: or a pharmaceutically acceptable salt thereof, wherein: Q is fluoro, chloro, bromo, or iodo; s is an integer from about 10 to about 100; b is an integer from about 10 to about 100; n is an integer from about 10 to about 100; v is an integer from 1 to about 20; j is an integer from 1 to about 20; p is an integer from 1 to about 20; z is an integer from 1 to about 20; q is an integer from 1 to about 20; x is an integer from 1 to about 20; and m is an integer from 1 to about 20. Q is fluoro, chloro, bromo, or iodo; s is an integer from about 10 to about 100; b is an integer from about 10 to about 100; n is an integer from about 10 to about 100; v is an integer from 1 to about 20; j is an integer from 1 to about 20; p is an integer from 1 to about 20; z is an integer from 1 to about 20; q is an integer from 1 to about 20; x is an integer from 1 to about 20; and m is an integer from 1 to about 20.
A movement support apparatus that supports movement of a vehicle having an internal combustion engine and a motor as drive sources from a current location to a destination, wherein the movement support apparatus includes: a setup unit that sets up any driving mode of an EV mode in which the motor using a battery is used as the drive source and an HV mode in which at least the internal combustion engine is used as the drive source for each section, into which a driving route from the current location to the destination is partitioned, when a running load for running in each section is set; and a change unit that changes the driving mode in a part of each section of the driving route to a driving mode other than the driving mode set up by the setup unit based on at least one of a running environment including a running state of the vehicle and a road environment and the running load as consumption of the battery necessary for running in the EV mode, and characterized in that the change unit changes the driving mode of the section, for which the EV mode is set up, to the HV mode on a condition that the vehicle is decelerated and then accelerated in the section, for which the EV mode is setup. a setup unit that sets up any driving mode of an EV mode in which the motor using a battery is used as the drive source and an HV mode in which at least the internal combustion engine is used as the drive source for each section, into which a driving route from the current location to the destination is partitioned, when a running load for running in each section is set; and a change unit that changes the driving mode in a part of each section of the driving route to a driving mode other than the driving mode set up by the setup unit based on at least one of a running environment including a running state of the vehicle and a road environment and the running load as consumption of the battery necessary for running in the EV mode, and characterized in that the change unit changes the driving mode of the section, for which the EV mode is set up, to the HV mode on a condition that the vehicle is decelerated and then accelerated in the section, for which the EV mode is setup.
A linear generator for submerged use in a sea and having a stator and a linearly reciprocating translator, which translator is attached to connection means (3, 7) arranged to connect the translator to a floating body on the sea surface, the generator having a sealed housing forming a water-tight chamber, in which the translator 6) is located, which connection means (3, 7) is arranged to pass through a sealed opening in a wall portion of the housing, characterized in that at operation, the wall portion with said sealed opening is located at a level that is below the level of the upper end of the translator at least during a part of the movement of the translator.
A nonaqueous electrolyte suitable for lithium ion secondary cells, comprising an electrolyte salt and nonaqueous solvents comprising (i) a fluorine-containing ether of the formula Rf 1 -O-Rf 2 wherein Rf 1 and Rf 2 each independently are selected from C 1-10 -alkyl and C 1-10 -fluoroalkyl; and at least one of Rf 1 and Rf 2 is fluoroalkyl, wherein the nonaqueous solvents contain 0.01-90 wt.-% of the fluorine-containing ether of formula, (ii) a total of 0.5 parts by weight or less of a fluorine-containing unsaturated compound and a hydroxy group-containing compound of the formula Rf 1 OH wherein Rf 1 is the same as above, relative to 100 parts by weight of the fluorine-containing ether, wherein the fluorine-containing ether is HCF 2 CF 2 CH 2 -O-CF 2 CF 2 H, the compound comprises CF 2 =CFCH 2 -O-CF 2 CF 2 H and HCF 2 CF=CH-O-CF 2 CF 2 H, and the hydroxy group-containing compound is HCF 2 CF 2 CH 2 OH; or the fluorine-containing ether is HCF 2 CF 2 CH 2 -O-CF 2 CFHCF 3, the fluorine-containing unsaturated compound comprises CF 2 =CFCH 2 -OCF 2 CFHCF 3, HCF 2 CF 2 CH 2 -O-CF=CFCF 3, HCF 2 CF 2 CH 2 -O-CF 2 CF=CF 2 and HCF 2 CF=CH-O-CF 2 CFHCF 3, and the hydroxy group-containing compound is HCF 2 CF 2 CH 2 OH (II-1). (i) a fluorine-containing ether of the formula Rf 1 -O-Rf 2 wherein Rf 1 and Rf 2 each independently are selected from C 1-10 -alkyl and C 1-10 -fluoroalkyl; and at least one of Rf 1 and Rf 2 is fluoroalkyl, wherein the nonaqueous solvents contain 0.01-90 wt.-% of the fluorine-containing ether of formula, (ii) a total of 0.5 parts by weight or less of a fluorine-containing unsaturated compound and a hydroxy group-containing compound of the formula Rf 1 OH wherein Rf 1 is the same as above, relative to 100 parts by weight of the fluorine-containing ether,
A control module (101, 104) for connection to a vehicle to enable a remote computing system to wirelessly communicate instructions to the vehicle via the control module, the control module comprising: one or more processors; a wireless network interface configured to interface the processor with a wireless network; a vehicle interface configured to interface the processor with an on-board diagnostics, "OBD", unit and a controller area network, "CAN", bus of the vehicle, the vehicle interface comprising a plurality of CAN bus transceivers (577, 578, 579), each CAN bus transceiver configured to interface the processor with a CAN bus type of at least one vehicle type such that the plurality of CAN bus transceivers are configured to interface the processor with the CAN bus types of a plurality of different vehicle types in the aggregate; and a data storage unit, the data storage unit in communication with the processor, the data storage unit comprising non-transitory computer storage comprising code executable by the processor; wherein the executable code is configured, upon execution by the processor, to cause the processor to: automatically detect an identifier for the vehicle through the vehicle interface; automatically select a CAN bus transceiver from among the plurality of CAN bus transceivers based on the detected identifier; and communicate with the vehicle's CAN bus via the selected CAN bus transceiver. one or more processors; a wireless network interface configured to interface the processor with a wireless network; a vehicle interface configured to interface the processor with an on-board diagnostics, "OBD", unit and a controller area network, "CAN", bus of the vehicle, the vehicle interface comprising a plurality of CAN bus transceivers (577, 578, 579), each CAN bus transceiver configured to interface the processor with a CAN bus type of at least one vehicle type such that the plurality of CAN bus transceivers are configured to interface the processor with the CAN bus types of a plurality of different vehicle types in the aggregate; and a data storage unit, the data storage unit in communication with the processor, the data storage unit comprising non-transitory computer storage comprising code executable by the processor; wherein the executable code is configured, upon execution by the processor, to cause the processor to: automatically detect an identifier for the vehicle through the vehicle interface; automatically select a CAN bus transceiver from among the plurality of CAN bus transceivers based on the detected identifier; and communicate with the vehicle's CAN bus via the selected CAN bus transceiver. automatically detect an identifier for the vehicle through the vehicle interface; automatically select a CAN bus transceiver from among the plurality of CAN bus transceivers based on the detected identifier; and communicate with the vehicle's CAN bus via the selected CAN bus transceiver.