mhurhangee/ep-ind-claims huggingface dataset:
A compound having the formula: wherein R 1 is substituted or unsubstituted C 1-10 alkyl, alkenyl, or alkynyl, or substituted or unsubstituted aryl or heteroaryl; R 2 is H, -CH 2 O-C 1-4 alkyl; COO-C 1-4 alkyl; -CONR 4; R 3 is H, substituted or unsubstituted C 1 -C 10 alkyl, alkynyl, or substituted or unsubstituted aryl or hetaryl; A is substituted or unsubstituted C 1-10 alkylene, alkynylene; Ar or HetAr is substituted or unsubstituted monocyclic or polycyclic aromatic or heteroaromatic moiety; COOR 5, or CON(R 6) 2, where R 5 and R 6 are H, substituted or unsubstituted C 1 -C 10 alkyl, alkynyl, or substituted or unsubstituted aryl or hetaryl; the central nitrogen-containing ring is a substituted or un substituted 5- to 7-membered heterocyclic ring; and pharmaceutically acceptable salts of said compound; for use in the treament of a clinical condition associated with opioid abuse, a development of opioid tolerance and dependence, opioid-induced constipation, alcohol abuse, opioid abuse, cocaine abuse, depression, opioid induced immune response depression, opioid-overdose-induced respiratory depression, nicotine withdrawal symptoms, obesity, psychosis, dyskinesia associated with Parkinson's disease, Raynaud's disease, scleroderma or a combination thereof, through modulation of μ-, δ-, k-opioid receptors and α2-adrenoreceptors. R 1 is substituted or unsubstituted C 1-10 alkyl, alkenyl, or alkynyl, or substituted or unsubstituted aryl or heteroaryl; R 2 is H, -CH 2 O-C 1-4 alkyl; COO-C 1-4 alkyl; -CONR 4; R 3 is H, substituted or unsubstituted C 1 -C 10 alkyl, alkynyl, or substituted or unsubstituted aryl or hetaryl; A is substituted or unsubstituted C 1-10 alkylene, alkynylene; Ar or HetAr is substituted or unsubstituted monocyclic or polycyclic aromatic or heteroaromatic moiety; COOR 5, or CON(R 6) 2, where R 5 and R 6 are H, substituted or unsubstituted C 1 -C 10 alkyl, alkynyl, or substituted or unsubstituted aryl or hetaryl; the central nitrogen-containing ring is a substituted or un substituted 5- to 7-membered heterocyclic ring; and pharmaceutically acceptable salts of said compound; for use in the treament of a clinical condition associated with opioid abuse, a development of opioid tolerance and dependence, opioid-induced constipation, alcohol abuse, opioid abuse, cocaine abuse, depression, opioid induced immune response depression, opioid-overdose-induced respiratory depression, nicotine withdrawal symptoms, obesity, psychosis, dyskinesia associated with Parkinson's disease, Raynaud's disease, scleroderma or a combination thereof, through modulation of μ-, δ-, k-opioid receptors and α2-adrenoreceptors.
A distributed load balancer system, comprising: one or more processors with associated memory that implement an ingress node, configured to: receive a packet of a packet flow from a client; determine that the packet flow is not currently mapped to any of a plurality of server nodes in mappings stored by the ingress node; identify a flow tracker node for the packet flow by selecting the flow tracker node from a plurality of load balancer nodes according to a consistent hash function applied to attributes of the packet flow, including the packet flow's source address, source port, destination address, and destination port; send data in the packet to the flow tracker node; obtain from the flow tracker node connection information for a connection to a server node from the plurality of server nodes mapped to the packet flow; record a mapping for the packet flow and the server node in the mappings; and forward packets in the packet flow to the server node according to the mapping; and one or more processors with associated memory that implement the flow tracker node, configured to: cause the connection to be opened to the server node for the packet flow. one or more processors with associated memory that implement an ingress node, configured to: receive a packet of a packet flow from a client; determine that the packet flow is not currently mapped to any of a plurality of server nodes in mappings stored by the ingress node; identify a flow tracker node for the packet flow by selecting the flow tracker node from a plurality of load balancer nodes according to a consistent hash function applied to attributes of the packet flow, including the packet flow's source address, source port, destination address, and destination port; send data in the packet to the flow tracker node; obtain from the flow tracker node connection information for a connection to a server node from the plurality of server nodes mapped to the packet flow; record a mapping for the packet flow and the server node in the mappings; and forward packets in the packet flow to the server node according to the mapping; and receive a packet of a packet flow from a client; determine that the packet flow is not currently mapped to any of a plurality of server nodes in mappings stored by the ingress node; identify a flow tracker node for the packet flow by selecting the flow tracker node from a plurality of load balancer nodes according to a consistent hash function applied to attributes of the packet flow, including the packet flow's source address, source port, destination address, and destination port; send data in the packet to the flow tracker node; obtain from the flow tracker node connection information for a connection to a server node from the plurality of server nodes mapped to the packet flow; record a mapping for the packet flow and the server node in the mappings; and forward packets in the packet flow to the server node according to the mapping; one or more processors with associated memory that implement the flow tracker node, configured to: cause the connection to be opened to the server node for the packet flow.
A sweetener composition comprised of: a) monk fruit extract comprising mogroside V; b) rebaudioside A; and c) rebaudioside B; wherein: the monk fruit extract, rebaudioside A and rebaudioside B are present in a weight ratio of monk fruit extract: (rebaudioside A + rebaudioside B) of 51:49 to 99:1; the mogroside V and rebaudioside A are present in a weight ratio of from 41:59 to 99:1 mogroside V: rebaudioside A; and the rebaudioside B is present in an amount of at least 2 weight % based on the total weight of a), b), c) and any additional steviol glycosides present. a) monk fruit extract comprising mogroside V; b) rebaudioside A; and c) rebaudioside B; the monk fruit extract, rebaudioside A and rebaudioside B are present in a weight ratio of monk fruit extract: (rebaudioside A + rebaudioside B) of 51:49 to 99:1; the mogroside V and rebaudioside A are present in a weight ratio of from 41:59 to 99:1 mogroside V: rebaudioside A; and the rebaudioside B is present in an amount of at least 2 weight % based on the total weight of a), b), c) and any additional steviol glycosides present.
A locking device for line connectors, comprising: a first housing and a second housing, which can be placed against one another in an engagement direction; a set of elastic locking clips, which are retained on the first housing by fastening members and can be locked with snap action on locking protrusions of the second housing; and an unlocking ring, which can be displaced on the first housing and the second housing in the engagement direction and has unlocking slopes for transferring the locking clips into an unlocked position, characterized in that the fastening members and the locking protrusions are pins (24, 34) which are embedded in circumferential walls of the first housing and the second housing.
A brassiere including: two cups attached to one another by a central link, including on each side: a lateral band affixed onto a side of one of the two cups, the lateral band terminating rearward with a central rear hook for catching the lateral bands to one another, a strap supporting an upper part of the cup in front, characterized in that the strap extends forward via an internal reinforcement edge meeting the central link and via an external reinforcement edge separate from the cup forming an upper contour of the lateral band which extends, descending continuously to the central rear hook, the lateral band rising upward to a top of the cup between the external edge and said cup, the brassiere furthermore including a support edge which, starting underneath the cup, extends outwardly, rising continuously to terminate at a rear attachment point of the strap, said support edge forming an upper contour of a support piece independent of the lateral band. a lateral band affixed onto a side of one of the two cups, the lateral band terminating rearward with a central rear hook for catching the lateral bands to one another, a strap supporting an upper part of the cup in front, characterized in that the strap extends forward via an internal reinforcement edge meeting the central link and via an external reinforcement edge separate from the cup forming an upper contour of the lateral band which extends, descending continuously to the central rear hook, the lateral band rising upward to a top of the cup between the external edge and said cup, the brassiere furthermore including a support edge which, starting underneath the cup, extends outwardly, rising continuously to terminate at a rear attachment point of the strap, said support edge forming an upper contour of a support piece independent of the lateral band.
An anti-properdin antibody or antigen binding portion thereof that binds specifically to SEQ ID NO: 2 and blocks the alternative pathway activation without affecting the classical pathway activation in a mammal for use in a method of ameliorating a disease or condition associated with excessive or uncontrolled alternative pathway complement activation in the mammal.
A base station, BS, device, connected to one or more cable modem, CM, devices of a fiber/coaxial cable hybrid network access network, DOCSIS network, at a reference point CMCI or to a cable modem terminal system, CMTS, device of a fiber/coaxial cable hybrid network access network, DOCSIS network at a reference point CMRFI and adapted to accomplish radio access processing of a wireless subscriber, perform a base station control processing on data packets or frames of the accessed wireless subscriber, deliver the processed data packets or frames to the one or more CM devices or to the CMTS device, perform the base station control processing on data packets or frames delivered from the one or more CM devices or from the CMTS device and output the processed data packets or frames to the wireless subscriber; wherein the BS further comprises: a base station remote power supply unit, adapted to convert a high-voltage DC from a remote power supply device or a remote power supply unit of the one or more cable modem devices or a remote power supply unit of the CMTS device into a low-voltage DC, so as to supply power to a power supply unit of the BS device, or to relay the high-voltage DC to remote BS devices at the next tier via wired cables; characterized in that the base station remote power supply unit is further adapted to support intercommunication with the remote power supply device, so as to serve as an out-band management channel for the BS device. a base station remote power supply unit, adapted to convert a high-voltage DC from a remote power supply device or a remote power supply unit of the one or more cable modem devices or a remote power supply unit of the CMTS device into a low-voltage DC, so as to supply power to a power supply unit of the BS device, or to relay the high-voltage DC to remote BS devices at the next tier via wired cables; characterized in that the base station remote power supply unit is further adapted to support intercommunication with the remote power supply device, so as to serve as an out-band management channel for the BS device.
Air turbine for applications in wave energy conversion associated with a pressure difference between a first space and a second space of alternately changing sign, comprising a rotor with a first rotor blade row and a second rotor blade row, axially offset from each other, circumferentially mounted on a hub fixed to a shaft, and a stator with a first row of guide vanes and second row of guide vanes, in which a first blade set consists of the first rotor blade row and of the first stator guide vane row, and a second blade set consists of the second rotor blade row and of the second stator guide vane row, the following applying to said turbine: a) its first stator guide vane row is connected to the first space through a first inlet duct, and its second stator guide vane row is connected to the second space through a second inlet duct; b) its first rotor blade row is connected to the second space through a first curved-walled unbladed duct, through a first outlet duct formed by two walls of revolution, shaped as plane or non-plane discs, and through a first set of n curved-axis ducts disposed circumferentially around the first outlet duct, n being an integer between 2 and 30; c) its second rotor blade row is connected to the first space through a second curved-walled unbladed duct, through a second outlet duct: formed by two walls of revolution, shaped as plane or non-plane discs, and through a second set of n curved-axis ducts disposed circumferentially around the second outlet duct; d) the n ducts of the first set of curved axis ducts, open to the second space, alternate circumferentially with the n ducts of the second set of curved-axis ducts open to the first space. a) its first stator guide vane row is connected to the first space through a first inlet duct, and its second stator guide vane row is connected to the second space through a second inlet duct; b) its first rotor blade row is connected to the second space through a first curved-walled unbladed duct, through a first outlet duct formed by two walls of revolution, shaped as plane or non-plane discs, and through a first set of n curved-axis ducts disposed circumferentially around the first outlet duct, n being an integer between 2 and 30; c) its second rotor blade row is connected to the first space through a second curved-walled unbladed duct, through a second outlet duct: formed by two walls of revolution, shaped as plane or non-plane discs, and through a second set of n curved-axis ducts disposed circumferentially around the second outlet duct; d) the n ducts of the first set of curved axis ducts, open to the second space, alternate circumferentially with the n ducts of the second set of curved-axis ducts open to the first space.
A method comprising: obtaining, by a power transmitter of a telephone base, a handset identifier provided by a wireless handset via a power receiver that is wirelessly coupled to the power transmitter for wireless charging of the wireless handset; determining whether the handset identifier matches a stored identifier; and based, in part, on the handset identifier matching the stored identifier, performing, by the telephone base, hook switching on behalf of the wireless handset. obtaining, by a power transmitter of a telephone base, a handset identifier provided by a wireless handset via a power receiver that is wirelessly coupled to the power transmitter for wireless charging of the wireless handset; determining whether the handset identifier matches a stored identifier; and based, in part, on the handset identifier matching the stored identifier, performing, by the telephone base, hook switching on behalf of the wireless handset.
Method for supporting the selection of communication peers in an overlay network, wherein a multitude of communication peers participate in said overlay network by providing certain pieces of information, wherein a first of said communication peers is a requesting client located on an access network of a first Internet Service Provider, wherein at least one peer-to-peer server operates as a tracker that maintains a database of said participating communication peers and the information possessed by said participating communication peers, wherein a network entity is provided that is located such that it receives messages directed from said requesting client to said tracker, wherein at least one message sent from said requesting client to said tracker is configured to include a location field that is marked as empty or invalid, wherein said network entity, upon detecting a message of said requesting client including a location field marked as empty or invalid, stamps said message by overwriting the content of said location field with valid topological location information of said requesting client, wherein said valid topological location information includes at least one of the identification of the requesting client's Internet Service Provider, the requesting client's Autonomous System Number, the requesting client's main distribution frame ID, the requesting client's Digital Subscriber Line Access Multiplexer/Multi-Service Access Node, x,y-coordinates of the requesting client within an area and the requesting client's line ID, wherein said network entity forwards said message, with the stamped topological location information, to said tracker, wherein said tracker, upon receiving said message including topological location information of said requesting client, extracts the topological location information by means of a location information retrieval module and stores it in a local database for a configurable length of time, wherein said requesting client sends a query regarding a specific piece of information to said tracker, wherein said tracker, upon receiving said query regarding the specific piece of information from said requesting client, answers said query by providing said requesting client a list that includes a subset of all communication peers possessing said requested piece of information, wherein said tracker's answer is constructed by selecting said subset of communication peers by using a peer selection module that calculates the communication peers that can best serve future requests of said requesting client based on knowledge said tracker has gained about the relative topological location between said requesting client and the communication peers.
Assembly comprising a. a housing for a refrigerator and/or a freezer; b. a door that is articulated to the housing so as to be pivotable about a pivot axis of a hinge (3; 3c) of the assembly, wherein the hinge (3; 3c) is articulated to the door by means of a first joint so as to be pivotable about an axis parallel to the pivot axis, and c. at least one drive device (5; 5c) for pivoting the door in relation to the housing, d. wherein the drive device (5; 5c) comprises a drive unit by means of which, in order to open the door and to close the door, a torque is applicable to the door in relation to the hinge axis by means of a force transmission means (14; 51) in such a way that the at least one force transmission means (14; 51) is displaceable linearly along an opening direction of the force transmission means (14; 51), characterised in that - the drive device (5; 5c) is integrated in the door, - the hinge (3; 3c) comprises a first leaf (8; 8c) articulated to the door by means of the first joint, and a second leaf (9; 9c) articulated to the housing by means of a second joint, - the first leaf (8; 8c) and the second leaf (9; 9c) being connected to each other, via a third joint, in such a way as to be pivotable, and - the at least one force transmission means (14; 51) is articulated to the first leaf (8; 8c) of the hinge (3; 3c). a. a housing for a refrigerator and/or a freezer; b. a door that is articulated to the housing so as to be pivotable about a pivot axis of a hinge (3; 3c) of the assembly, wherein the hinge (3; 3c) is articulated to the door by means of a first joint so as to be pivotable about an axis parallel to the pivot axis, and c. at least one drive device (5; 5c) for pivoting the door in relation to the housing, d. wherein the drive device (5; 5c) comprises a drive unit by means of which, in order to open the door and to close the door, a torque is applicable to the door in relation to the hinge axis by means of a force transmission means (14; 51) in such a way that the at least one force transmission means (14; 51) is displaceable linearly along an opening direction of the force transmission means (14; 51), characterised in that - the drive device (5; 5c) is integrated in the door, - the hinge (3; 3c) comprises a first leaf (8; 8c) articulated to the door by means of the first joint, and a second leaf (9; 9c) articulated to the housing by means of a second joint, - the first leaf (8; 8c) and the second leaf (9; 9c) being connected to each other, via a third joint, in such a way as to be pivotable, and - the at least one force transmission means (14; 51) is articulated to the first leaf (8; 8c) of the hinge (3; 3c). - the drive device (5; 5c) is integrated in the door, - the hinge (3; 3c) comprises a first leaf (8; 8c) articulated to the door by means of the first joint, and a second leaf (9; 9c) articulated to the housing by means of a second joint, - the first leaf (8; 8c) and the second leaf (9; 9c) being connected to each other, via a third joint, in such a way as to be pivotable, and - the at least one force transmission means (14; 51) is articulated to the first leaf (8; 8c) of the hinge (3; 3c).
A composition comprising a polymer nanoparticle and at least one organic agricultural active compound associated with the polymer nanoparticle, wherein the polymer nanoparticle is less than 100 nm in diameter and is cross-linked, and wherein the polymer nanoparticle comprises a collapsed, water-soluble polyelectrolyte that has a molecular weight of between 100,000 Dalton and 250,000 Dalton.
A pretensioner comprising: a ring gear to which a spool is rotatably disposed, the spool winding a webbing for restraining an occupant; and power transmission units for transmitting power to the ring gear in an emergency, wherein the power transmission units comprise a rod-shaped power transmission member for transmitting power to the ring gear while being plastically deformed, a tip reinforcing member disposed on a tip side of the power transmission member, a pipe for containing the power transmission member, and a gas generator disposed at an end of the pipe, and the tip reinforcing member has higher tensile strength, yield strength, and hardness than the power transmission member; characterized in that the tip reinforcing member is formed such that a length with respect to an axial direction of the power transmission member is smaller than a pitch of the ring gear. a ring gear to which a spool is rotatably disposed, the spool winding a webbing for restraining an occupant; and power transmission units for transmitting power to the ring gear in an emergency, wherein the power transmission units comprise a rod-shaped power transmission member for transmitting power to the ring gear while being plastically deformed, a tip reinforcing member disposed on a tip side of the power transmission member, a pipe for containing the power transmission member, and a gas generator disposed at an end of the pipe, and the tip reinforcing member has higher tensile strength, yield strength, and hardness than the power transmission member; characterized in that the tip reinforcing member is formed such that a length with respect to an axial direction of the power transmission member is smaller than a pitch of the ring gear.
A fuel composition comprising greater than 50 wt. % of a hydrocarbon fuel boiling in gasoline or diesel range and 25 to 5000 ppm by weight of one or more primary or secondary amino alkanediol or an alkyl carboxylic acid salt of the primary or secondary amino alkanediol, wherein structure of the amino alkanediol is wherein R 1 is an H or an aliphatic group, wherein the aliphatic group is one of the following hydrocarbon chain: pentyl group, hexyl group, heptan-2-yl group, 2-methylhexyl group, 2-ethylhexyl group, or 4-methylhexyl group.