mhurhangee/ep-ind-claims huggingface dataset:
A device (1, 2) for controlling or regulating an ultrafiltration in a dialysis treatment, in which the blood to be ultrafiltered flows through a blood chamber of a dialyzer that is subdivided by a semipermeable membrane into the blood chamber and a dialysis fluid chamber in an extracorporeal blood circulation, and dialysis fluid in a dialysis fluid circulation flows through the dialysis fluid chamber of the dialyzer, having a blood pump for generating a blood flow in the extracorporeal blood circulation, having a dialysis fluid pump for generating a dialysis fluid flow in the dialysis fluid circulation, having a balancing device for setting up a liquid balance in the dialysis fluid circulation between the inflow and an outflow of the dialysis fluid chamber as a measure of the ultrafiltration, characterized by a regulating unit for regulating the blood pump and/or the dialysis fluid pump, so that a predetermined ultrafiltration is achieved without further active control or regulation of the dialysis fluid flow coming out of the dialyzer, wherein the dialysis fluid pump is arranged in an inlet line to the dialysis fluid chamber, and there is no further active control or regulation of the dialysis fluid flow downstream from the dialysis fluid chamber.
A method for improving the aesthetic appearance of skin affected by aging comprising topically applying thereto an effective amount of a pH-dependent film-forming polymer of poly(methacrylic acid-co-methyl methacrylate) with a ratio of methacrylic acid to methyl methacrylate of 1:1 to 1:2, an acid value of from 150 to 350 mg KOH/g, and a weight average molar mass between 100,000 and 150,000 g/mol, in a cosmetically acceptable vehicle for a time sufficient to achieve a tightening effect.
A transport apparatus for transporting an elongated strip-sha ped recording medium along the length thereof, comprising: a detector for detecting a widthwise position of said recording medium, said detector providing a detection result indicative of the widthwise position; and a correction mechanism for correcting the widthwise position of said recording medium, based on said detection result from said detector; and characterized in that said transport apparatus further comprising a meandering attenuator for attenuating the periodic meandering of said recording medium in a position upstream or downstream of said correction mechanism as seen in a transport direction, said meandering attenuator including a plurality of attenuation rollers rotating while being in contact with said recording medium. a detector for detecting a widthwise position of said recording medium, said detector providing a detection result indicative of the widthwise position; and a correction mechanism for correcting the widthwise position of said recording medium, based on said detection result from said detector; and characterized in that said transport apparatus further comprising a meandering attenuator for attenuating the periodic meandering of said recording medium in a position upstream or downstream of said correction mechanism as seen in a transport direction, said meandering attenuator including a plurality of attenuation rollers rotating while being in contact with said recording medium.
A chassis (10, 50) for a vehicle comprising a framework of interconnected tubular sections (14, 18) and at least one composite sheet bonded to the framework, characterised in that at least part (78, 80) of the composite sheet comprises fibres arranged unidirectionally, the part (78, 80) of the composite sheet comprising unidirectional fibres extending obliquely rearwardly from one side of the chassis towards another side, the unidirectional fibres also being oriented obliquely rearwardly in the same sense.
Steering column for a motor vehicle, comprising a jacket unit in which a steering spindle is mounted rotatably about a longitudinal axis extending in the longitudinal direction and which has at least two jacket tubes (31, 32, 33) with a polygonal cross-section which are displaceably which are guided adjustably relative to one another in the longitudinal direction, wherein rolling elements (7, 8) having a rolling element radius (k) are arranged between the casing tubes (31, 32, 33) in raceways (34, 35, 36, 37) of a rolling element guide so as to roll in the longitudinal direction, wherein at least three raceways (34, 35, 36, 37) are arranged distributed over the circumference characterized in that the center points (K1, K2) of the rolling elements (7, 8) which can be rolled radially on the outside of a casing tube (32, 33) have a radial distance (a, b) less than or equal to the rolling element radius (k) from an enveloping circle (90, 93) which circumscribes the casing tube (32, 33) on which the rolling elements can be rolled on the outside. at least three raceways (34, 35, 36, 37) are arranged distributed over the circumference characterized in that the center points (K1, K2) of the rolling elements (7, 8) which can be rolled radially on the outside of a casing tube (32, 33) have a radial distance (a, b) less than or equal to the rolling element radius (k) from an enveloping circle (90, 93) which circumscribes the casing tube (32, 33) on which the rolling elements can be rolled on the outside.
Cable duct for power and supply lines, comprising - a lower part having - base, - two side walls, and - lid-retaining profiles that are configured on the side walls, - an upper part having shaped profiles which cooperate with the lid-retaining profiles of the lower part, - one leg that is inwardly inclined in a U-shape toward the duct centre being configured on each of the ends of the upper part on the longitudinal sides, - the legs forming leg receptacles, - a retrievable visual element being guided in the leg receptacles, - the shaped profiles of the upper part and the legs that are inwardly inclined in a U-shape each being connected by way of a web, characterized in that - the visual element is transparent, - a rear element, preferably graphics, an image, or a photographic illustration, that is guided in the leg receptacles is disposed behind the visual element, - the lid-retaining profiles of the lower part are configured as U-shaped tabs from individual angled leg elements that face away from the base, in which tabs the shaped profiles of the upper part engage, wherein the shaped profiles comprise leg elements, and the leg elements of the lid-retaining profiles with the leg elements of the shaped profiles come to bear on contact faces (26.1, 26.2, 26.3) and are supported on the latter. - a lower part having - base, - two side walls, and - lid-retaining profiles that are configured on the side walls, - base, - two side walls, and - lid-retaining profiles that are configured on the side walls, - an upper part having shaped profiles which cooperate with the lid-retaining profiles of the lower part, - one leg that is inwardly inclined in a U-shape toward the duct centre being configured on each of the ends of the upper part on the longitudinal sides, - the legs forming leg receptacles, - a retrievable visual element being guided in the leg receptacles, - the shaped profiles of the upper part and the legs that are inwardly inclined in a U-shape each being connected by way of a web, - the visual element is transparent, - a rear element, preferably graphics, an image, or a photographic illustration, that is guided in the leg receptacles is disposed behind the visual element, - the lid-retaining profiles of the lower part are configured as U-shaped tabs from individual angled leg elements that face away from the base, in which tabs the shaped profiles of the upper part engage, wherein the shaped profiles comprise leg elements, and the leg elements of the lid-retaining profiles with the leg elements of the shaped profiles come to bear on contact faces (26.1, 26.2, 26.3) and are supported on the latter.
A multi-targeted molecule comprising a first double-stranded siRNA molecule and a second double-stranded siRNA molecule, wherein the sense strand of the first siRNA comprises a single-strand overhang at its 3'-end and the antisense strand of the second siRNA comprises a single-strand overhang at its 3'-end, wherein the nucleic acid sequence of the single-strand overhang of the sense strand is substantially complementary to the nucleotide sequence of the single-strand overhang of the antisense strand, wherein the length of the substantially complementary sequence ranges from 5 to 25 nucleotides, and wherein the two single-strand overhangs form a duplex, and wherein the first siRNA and the second siRNA are each conjugated with at least one ligand, wherein the single-stranded overhang of the sense strand comprises all DNA, all RNA or a mixture of DNA and RNA nucleotides, and wherein the DNA and RNA can be natural or modified.
Optical system (100; 200; 300) for a motor vehicle headlight or other light, said optical system producing at least one main optical function and notably comprising: - a diffusion screen, also called light guide (113; 313); - at least one light source, notably of LED type (101; 201; 301), each light source of the optical system producing a set of light rays (102; 202) that are propagated in the diffusion screen; characterized in that: - the screen (113; 313) has a curved sheet or substantially planar form, with a top lateral cheek (108; 308) and a bottom lateral cheek which are joined via a perimeter having a rear face (107; 207; 307) and a front rim (104; 304); - the main function is produced essentially via an output face composed of the front rim (104; 304) of the diffusion screen (113; 313); and - at least a part of the top lateral cheek (108; 308) diffuses a light beam notably contributing to the production of the main function and/or producing an additional optical projection function; and - said part is oriented so as to increase the visible lit surface of the optical system in the direction of emission of the light of the main function. - a diffusion screen, also called light guide (113; 313); - at least one light source, notably of LED type (101; 201; 301), each light source of the optical system producing a set of light rays (102; 202) that are propagated in the diffusion screen; - the screen (113; 313) has a curved sheet or substantially planar form, with a top lateral cheek (108; 308) and a bottom lateral cheek which are joined via a perimeter having a rear face (107; 207; 307) and a front rim (104; 304); - the main function is produced essentially via an output face composed of the front rim (104; 304) of the diffusion screen (113; 313); and - at least a part of the top lateral cheek (108; 308) diffuses a light beam notably contributing to the production of the main function and/or producing an additional optical projection function; and - said part is oriented so as to increase the visible lit surface of the optical system in the direction of emission of the light of the main function.
A method of controlling an electric heater in an electrically heated smoking system, the method comprising the steps: providing electrical power to the heater in pulses such that during active periods power is supplied to the heater and during inactive periods, power is not supplied to the heater; charging a capacitor in an RC circuit during inactive periods and allowing the capacitor to discharge during active periods; and monitoring a discharge voltage of the capacitor and if the discharge voltage of the capacitor drops below a threshold voltage level, then stopping further supply of electrical power to the heater. providing electrical power to the heater in pulses such that during active periods power is supplied to the heater and during inactive periods, power is not supplied to the heater; charging a capacitor in an RC circuit during inactive periods and allowing the capacitor to discharge during active periods; and monitoring a discharge voltage of the capacitor and if the discharge voltage of the capacitor drops below a threshold voltage level, then stopping further supply of electrical power to the heater.
Method for maintaining the performance of a pneumatic vehicle tyre for winter or year-round use throughout its lifetime with a tread, which has profile elements and circumferential and/or transverse grooves arranged between these profile elements, wherein at least one profile element is provided with a sipe, which is arranged within the profile element, extends approximately in the radial direction (rR) from the tread periphery into the interior of the profile element and has corresponding sipe walls, wherein the circumferential and/or transverse grooves have a first depth and the sipe has a second depth, wherein the second depth lies in a range of 15% - 50% of the first depth and wherein the second depth is however at least 2 mm, characterized in that, after reaching its critical remaining depth, the sipe is regrooved in terms of its depth, preferably by means of a laser, wherein the sipe is regrooved in such a way that, after the regrooving, it has a second depth in a range of 15% - 50% of a first depth, remaining after the previous abrasive wear, of the circumferential and/or transverse grooves, wherein the regrooved second depth is however at least 2 mm.
A method for producing a tubular compression item, of sock, stocking or knee-length stocking, or panty hose type having at least one leg part, one foot tip, one heel, one foot and one ribbed edge in the extension of the leg part delimiting an opening for introducing the foot into said item, comprising the following steps: a. a first step for knitting the leg part, the foot and the ribbed edge with at least one knitting yarn on a double cylinder knitting machine comprising an upper cylinder and a lower cylinder each operating with (m) needles, during which several rows of ribbed stitches (n)*(p), (n')*(p') and (n")*(p") are respectively knitted for the leg part, the foot and the ribbed edge, (m), (n), (n'), (n"), (p), (p') and (p") being integers greater than or equal to 1, b. a step for inserting during the first knitting step an elastic weft yarn between two rows of ribbed stitches (n)*(p) and (n')*(p') every 1/1 to 1/5 rows of stitches of the leg part and of the foot and every 1/2 to 1/5 rows of stitches of the ribbed edge, on at least 50% by number of the number (m) of needles without forming any tuck stitch, or loop stitch, the weft yarn density in the ribbed edge being less than or equal to the weft yarn density in the leg part, c. a second step for knitting the foot tip and the heel on said double cylinder knitting machine with at least one knitting yarn and optionally an elastic weft yarn. a. a first step for knitting the leg part, the foot and the ribbed edge with at least one knitting yarn on a double cylinder knitting machine comprising an upper cylinder and a lower cylinder each operating with (m) needles, during which several rows of ribbed stitches (n)*(p), (n')*(p') and (n")*(p") are respectively knitted for the leg part, the foot and the ribbed edge, (m), (n), (n'), (n"), (p), (p') and (p") being integers greater than or equal to 1, b. a step for inserting during the first knitting step an elastic weft yarn between two rows of ribbed stitches (n)*(p) and (n')*(p') every 1/1 to 1/5 rows of stitches of the leg part and of the foot and every 1/2 to 1/5 rows of stitches of the ribbed edge, on at least 50% by number of the number (m) of needles without forming any tuck stitch, or loop stitch, the weft yarn density in the ribbed edge being less than or equal to the weft yarn density in the leg part, c. a second step for knitting the foot tip and the heel on said double cylinder knitting machine with at least one knitting yarn and optionally an elastic weft yarn.
A kit comprising a bone anchor and an injection cannula for use with said bone anchor, the bone anchor comprising a shaft having a first end and a second end, a channel (11, 12) extending from the first end to the second end, and a plug member (30, 40, 41) which is a separate part and which is insertable into the channel from the first end and guidable through the channel for closing the channel at the second end, the injection cannula comprising a tube portion adapted to be introduced at least partly into the channel (11, 12) and a connector portion adapted to be connected with a syringe for the injection of bone cement or other liquid or pasty material into the bone anchor, characterized in that the tube portion has an inner diameter which is large enough that the plug member is guidable therethrough.
A medical device system comprising: therapy delivery circuitry (270, 288, 420) configured to deliver anti-tachycardia pacing therapy to a heart of a patient via electrodes communicatively coupled to the therapy delivery circuitry, the ATP therapy comprising an ATP train; and processing circuitry (416, 264, 280) configured to: determine a first feature in a local electrogram; determine a second feature in a far-field electrogram; determine a first propagation time based on the first feature and the second feature; determine a number of pulses of the ATP train to achieve a second propagation time based on the first propagation time; and control the therapy delivery circuitry to deliver the ATP train of at least the number of pulses. therapy delivery circuitry (270, 288, 420) configured to deliver anti-tachycardia pacing therapy to a heart of a patient via electrodes communicatively coupled to the therapy delivery circuitry, the ATP therapy comprising an ATP train; and processing circuitry (416, 264, 280) configured to: determine a first feature in a local electrogram; determine a second feature in a far-field electrogram; determine a first propagation time based on the first feature and the second feature; determine a number of pulses of the ATP train to achieve a second propagation time based on the first propagation time; and control the therapy delivery circuitry to deliver the ATP train of at least the number of pulses. determine a first feature in a local electrogram; determine a second feature in a far-field electrogram; determine a first propagation time based on the first feature and the second feature; determine a number of pulses of the ATP train to achieve a second propagation time based on the first propagation time; and control the therapy delivery circuitry to deliver the ATP train of at least the number of pulses.
A hematopoietic stem cell, a hematopoietic progenitor cell, a myeloid/monocyte-committed progenitor cell, a macrophage or a monocyte comprising a vector wherein the vector comprises at least one mir-130a and/or mir-126 target sequence operably linked to a nucleotide sequence encoding a cytokine for use in treating or preventing a cancer in a patient, wherein the HSC, the HPC, the myeloid/monocyte-committed progenitor cell, the macrophage or the monocyte is used in combination with a tumor associated antigen -specific T-cell, preferably wherein the cytokine is an interferon, IL-12 or granulocyte-macrophage colony-stimulating factor (GM-CSF), preferably wherein the IFN is a type I IFN (preferably IFNα or IFNβ), or a type II IFN (preferably IFNγ), more preferably wherein the type I IFN is IFNα. preferably wherein the cytokine is an interferon, IL-12 or granulocyte-macrophage colony-stimulating factor (GM-CSF), preferably wherein the IFN is a type I IFN (preferably IFNα or IFNβ), or a type II IFN (preferably IFNγ), more preferably wherein the type I IFN is IFNα.
A Li-ion battery (2, 4, 6, 8) having fluorinated material comprising a solid fluoropolymer positioned effective to abate combustion by said battery, said fluorinated material being non-gaseous and non-liquid under normal conditions and being itself effective to provide the abatement of said combustion by said battery, characterized in that said fluorinated material further comprises a liquid fluoropolyether and said effective positioning forms a coating of said fluorinated material on at least a portion of said Li-ion battery.
A power tool, comprising: a motor configured to be rotatable in a forward direction and a reverse direction; a user operable trigger switch for operating the motor; a user operable reversing switch for choosing the direction of rotation of the motor; and a controller; characterised in that the controller is configured to determine a direction of rotation of the motor based on a characteristic of the motor, wherein the characteristic of the motor is voltage. a motor configured to be rotatable in a forward direction and a reverse direction; a user operable trigger switch for operating the motor; a user operable reversing switch for choosing the direction of rotation of the motor; and a controller; characterised in that the controller is configured to determine a direction of rotation of the motor based on a characteristic of the motor, wherein the characteristic of the motor is voltage.
An agricultural soil cultivation device comprising a support frame, on which a front row of at least six discs and a rear row of at least six discs is mounted, wherein the discs are of a disc shape with one convex side and mounted to the frame by means of tines, wherein the discs of the front row are oriented with their convex sides towards the central axis of the device and the discs of the rear row are oriented with their convex sides away from the central axis of the operating width, and wherein vertical chords of the discs form an angle α with the perpendicular towards the horizontal plane ranging from 14° to 22°, and horizontal chords of the discs form an angle β with the direction of travel of the device ranging from 14° to 22°, and wherein the discs of the same orientation of each row, are in the same distance, the discs of the front row located the closest to the central axis are arranged on a separate central tine of the front row, characterized in that the device further comprises a central row of discs with at least two discs mounted on a central tine of the central row arranged in between the front row and the rear row, wherein lines, horizontal and perpendicular to the central axis of the device, passing through the center of the discs of the central row, offset with each other by the length of the offset of the central discs by at least 20 mm, and the discs of the central row are oriented with their convex sides towards the central axis of the device, wherein the vertical chords of the discs of the central row form an angle -α with the perpendicular to the horizontal plane, and the horizontal chords of the discs form an angle β with the direction of travel of the device.
A polymer derivative of a cytidine metabolic antagonist bonding a substituent represented by the general formula or the general formula to a side-chain carboxy group of a block copolymer of a polyethylene-glycol structural moiety and a polymer having 10 or more carboxy groups wherein, R 7 and R 8 each independently represent a hydrogen atom or an optionally substituted (C1-C6)alkyl group, R 6 represents a hydrogen atom, an optionally substituted (C1-C40)alkyl group, an optionally substituted (C1-C40)aralkyl group, an optionally substituted aromatic group, an amino acid residue in which the carboxy group is protected, or an optionally substituted sugar residue, CX-CY represents CH-CH or C=C (double bond), and A represents the residue of the cytidine metabolic antagonist except the amino group at the position 4, wherein the cytidine metabolic antagonist is selected from the group consisting of gemcitabine, 5'-deoxy-5-fluorocytidine, cytarabine and 3'-ethynylcytidine.