A device for interaction between a laser beam and a hyperfine energy transition of a chemical species placed in a vacuum space, comprising: - a laser source adapted to emit a source laser beam at an initial optical frequency (wo), characterized in that the device further includes: - a single sideband electro-optic modulator comprising an input optical waveguide adapted to receive the source laser beam and an output optical waveguide adapted to generate an output laser beam, the electro-optic modulator having a first high-frequency electrode, another high-frequency electrode and a plurality of low-frequency electrodes (63a, 63b, 64), - a low-frequency voltage generator, configured to apply on each of said low-frequency electrodes a low-frequency voltage adapted to generate a predetermined optical phase-shift in the optical waveguide, and - an electronic system (75, 76) comprising a clock, the electronic system (75, 76) being adapted to generate a first electrical signal (sin(Ωt), sin(Ω 1 t)) modulated at a first pulse (Ω, Ω 1) and, respectively, another electrical signal (cos(Ωt), cos(Q 1 t)) modulated at the first pulse (Ω, Ω 1), synchronized by the clock, the electronic system (75, 76) being adapted to amplitude and phase-tune the first modulated electrical signal (sin(Ωt), sin(Ω 1 t)) with respect to the other electrical signal (cos(Ωt), cos(Q 1 t)) modulated at the first pulse (Ω, Ω 1), the electronic system (75, 76) being adapted to simultaneously apply the first electrical signal (sin(Ωt), sin(Ω 1 t)) modulated at the first pulse (Ω, Ω 1) to the first high-frequency electrode and, respectively, the other electrical signal (cos(Ωt), cos(Q 1 t)) modulated at the first pulse (Ω, Ω 1) to the other high-frequency electrode, and the electronic system (75, 76) being adapted to switch and tune the first pulse (Ω, Ω 1) in a microwave spectral range extending over at most 100 gigahertz so as to frequency-switch the output laser beam to a first optical frequency (wo+Q, ωο+Ω 1, ωο-Ω, ωο-Ω 1) shifted by the first pulse (Ω, Ω 1) with respect to the initial optical frequency (ωo) while attenuating the output laser beam at the initial optical frequency (ωo) and at the other harmonics of the first pulse (Ω, Ω 1) with respect to the initial optical frequency (ωo). - a laser source adapted to emit a source laser beam at an initial optical frequency (wo), - a single sideband electro-optic modulator comprising an input optical waveguide adapted to receive the source laser beam and an output optical waveguide adapted to generate an output laser beam, the electro-optic modulator having a first high-frequency electrode, another high-frequency electrode and a plurality of low-frequency electrodes (63a, 63b, 64), - a low-frequency voltage generator, configured to apply on each of said low-frequency electrodes a low-frequency voltage adapted to generate a predetermined optical phase-shift in the optical waveguide, and - an electronic system (75, 76) comprising a clock, the electronic system (75, 76) being adapted to generate a first electrical signal (sin(Ωt), sin(Ω 1 t)) modulated at a first pulse (Ω, Ω 1) and, respectively, another electrical signal (cos(Ωt), cos(Q 1 t)) modulated at the first pulse (Ω, Ω 1), synchronized by the clock, the electronic system (75, 76) being adapted to amplitude and phase-tune the first modulated electrical signal (sin(Ωt), sin(Ω 1 t)) with respect to the other electrical signal (cos(Ωt), cos(Q 1 t)) modulated at the first pulse (Ω, Ω 1), the electronic system (75, 76) being adapted to simultaneously apply the first electrical signal (sin(Ωt), sin(Ω 1 t)) modulated at the first pulse (Ω, Ω 1) to the first high-frequency electrode and, respectively, the other electrical signal (cos(Ωt), cos(Q 1 t)) modulated at the first pulse (Ω, Ω 1) to the other high-frequency electrode, and the electronic system (75, 76) being adapted to switch and tune the first pulse (Ω, Ω 1) in a microwave spectral range extending over at most 100 gigahertz so as to frequency-switch the output laser beam to a first optical frequency (wo+Q, ωο+Ω 1, ωο-Ω, ωο-Ω 1) shifted by the first pulse (Ω, Ω 1) with respect to the initial optical frequency (ωo) while attenuating the output laser beam at the initial optical frequency (ωo) and at the other harmonics of the first pulse (Ω, Ω 1) with respect to the initial optical frequency (ωo).