A fluidic dispensing device comprising: a body configured to have a chamber with a perimetrical end surface, and a chip mounting surface defining a first plane and having a first opening; an ejection chip configured to be coupled to the chip mounting surface, the ejection chip being configured to be in fluid communication with the first opening and to have a fluid ejection direction configured to be substantially orthogonal to the first plane; and a diaphragm configured to have a dome portion, dome deflection portions surrounding the dome portion, and a sealing surface, the sealing surface being configured to have a planar extent that surrounds the chamber, wherein the body further has a base wall that faces the diaphragm, the base wall is configured to be oriented along a second plane, the sealing surface is configured to be in sealing engagement with the perimetrical end surface to define a fluid reservoir in fluid communication with the first opening, the diaphragm is configured to have a deflection axis, and the dome portion is configured to be displaceable along the deflection axis, wherein the diaphragm is made of elastomeric material, the dome portion is configured to have a dome crown, and the dome crown is configured to be movable along the deflection axis to become concave during a displacement of the dome portion along the deflection axis toward the base wall, and the deflection axis is configured to be substantially perpendicular to the fluid ejection direction and is configured to be substantially perpendicular to the second plane, wherein the dome portion is configured to progressively collapse toward a base wall in the region of the dome deflection portions as fluid is depleted from the fluidic dispensing device, so as to maintain a desired negative pressure in the chamber, and thus changing the effective volume of the variable volume of fluid reservoir. a body configured to have a chamber with a perimetrical end surface, and a chip mounting surface defining a first plane and having a first opening; an ejection chip configured to be coupled to the chip mounting surface, the ejection chip being configured to be in fluid communication with the first opening and to have a fluid ejection direction configured to be substantially orthogonal to the first plane; and a diaphragm configured to have a dome portion, dome deflection portions surrounding the dome portion, and a sealing surface, the sealing surface being configured to have a planar extent that surrounds the chamber, wherein the body further has a base wall that faces the diaphragm, the base wall is configured to be oriented along a second plane, the sealing surface is configured to be in sealing engagement with the perimetrical end surface to define a fluid reservoir in fluid communication with the first opening, the diaphragm is configured to have a deflection axis, and the dome portion is configured to be displaceable along the deflection axis, wherein the diaphragm is made of elastomeric material, the dome portion is configured to have a dome crown, and the dome crown is configured to be movable along the deflection axis to become concave during a displacement of the dome portion along the deflection axis toward the base wall, and the deflection axis is configured to be substantially perpendicular to the fluid ejection direction and is configured to be substantially perpendicular to the second plane, wherein the dome portion is configured to progressively collapse toward a base wall in the region of the dome deflection portions as fluid is depleted from the fluidic dispensing device, so as to maintain a desired negative pressure in the chamber, and thus changing the effective volume of the variable volume of fluid reservoir.