A therapeutic instrument, for storing a sheet-type therapeutic substance therein, and delivering the stored therapeutic substance to an affected part, characterized by comprising: a nozzle member having a tubular part forming a space in which the therapeutic substance can be stored in a deformed state, and having an opening on a tip end of the tubular part for charging and discharging the therapeutic substance, and having a communication part on a rear end of the tubular part for communicating with the space of the tubular part; a pressure generator that selectively causes a negative pressure and a positive pressure to act in the tubular part of the nozzle member; a needle member having a hollow needle part inserted into the tubular part from a rear end side of the nozzle member, and capable of moving relatively to the nozzle member; and a supporting member fitted to a tip end of the needle member for supporting the therapeutic substance, wherein the space of the tubular part is the space for causing the negative pressure to act in the tubular part by the pressure generator to thereby suck the therapeutic substance into the tubular part, when the therapeutic substance is stored in the tubular part, the space is the space for causing the positive pressure to act in the tubular part by the pressure generator to thereby push-out the therapeutic substance to outside of the tubular part, when the therapeutic substance stored in the tubular part by sucking is delivered to the affected part, and the supporting member comprises a tongue-like member having a planar developed shape in a state that the tip end of the needle part is protruded to outside of the tubular part, and having a shape deformed into a roll-shape in contact with an edge of the opening of the tubular part when the tip end of the needle part is retracted into the tubular part from the opening. a nozzle member having a tubular part forming a space in which the therapeutic substance can be stored in a deformed state, and having an opening on a tip end of the tubular part for charging and discharging the therapeutic substance, and having a communication part on a rear end of the tubular part for communicating with the space of the tubular part; a pressure generator that selectively causes a negative pressure and a positive pressure to act in the tubular part of the nozzle member; a needle member having a hollow needle part inserted into the tubular part from a rear end side of the nozzle member, and capable of moving relatively to the nozzle member; and a supporting member fitted to a tip end of the needle member for supporting the therapeutic substance, wherein the space of the tubular part is the space for causing the negative pressure to act in the tubular part by the pressure generator to thereby suck the therapeutic substance into the tubular part, when the therapeutic substance is stored in the tubular part, the space is the space for causing the positive pressure to act in the tubular part by the pressure generator to thereby push-out the therapeutic substance to outside of the tubular part, when the therapeutic substance stored in the tubular part by sucking is delivered to the affected part, and the supporting member comprises a tongue-like member having a planar developed shape in a state that the tip end of the needle part is protruded to outside of the tubular part, and having a shape deformed into a roll-shape in contact with an edge of the opening of the tubular part when the tip end of the needle part is retracted into the tubular part from the opening.