A compound comprising a member selected from the group consisting of: wherein -LX is selected from the group consisting of -(CH 2)-(2-cyano)phenyl, -(CH 2)-(3-cyano)phenyl, -(CH 2)-(2-hydroxy)phenyl, -(CH 2)-(3-hydroxy)phenyl, -(CH 2)-(2-alkenyl)phenyl, -(CH 2)-(3-alkenyl)phenyl, -(CH 2)-(2-alkynyl)phenyl, -(CH 2)-(3-alkynyl)phenyl, -(CH 2)-(2-nitro)phenyl, -(CH 2)-(3-nitro)phenyl, -(CH 2)-(2-carboxy)phenyl, -(CH 2)-(3-carboxy)phenyl, -(CH 2)-(2-carboxamido)p henyl, -(CH 2)-(3-carboxamido)phenyl, -(CH 2)-(2-sulfonamido)phenyl, -(CH 2)-(3-sulfonamido)phenyl, -(CH 2)-( 2-tetrazolyl)phenyl, -(CH 2)-(3-tetrazolyl)phenyl, -(CH 2)-(2-aminomethyl)phenyl, -(CH 2)-(3-aminomethyl)phenyl, -(CH 2)-(2-amino)phenyl, -(CH 2)-(3-amino)phenyl, -(CH 2)-(2-hydroxymethyl)phenyl, -(CH 2)-(3-hydroxymethyl)phenyl, -(CH 2)-(2 -phenyl)phenyl, -(CH 2)-(3-phenyl)phenyl, -(CH 2)-(2-CONH 2)phenyl, -(CH 2)-(3-CONH 2)phenyl, -(CH 2)-(2-CONH(C 1-7) alkyl)phenyl, -(CH 2)-(3-CONH(C 1-7)alkyl)phenyl, -(CH 2)-(2-CO 2 (C 1-7)alkyl)phenyl, -(CH 2)-( 3-CO 2 (C 1-7)alkyl)phenyl, -CH 2 -NH 2, -CH 2 -OH, -CH 2 -(C 3-7)alkyl, -CH 2 -alkene, -CH 2 -alkyne, -CH 2 -CCH, -CH 2 -(C 3-7)cycloalkyl, and -CH 2 -aryl, each substituted or unsubstituted; Z is selected from the group consisting of 3-amino-piperidin-1-yl, 3-aminomethyl-pyrrolidin-1-yl, 2-aminoazetidin-1-yl, 3-aminoazetidin-1-yl, 3-amino-3-methylpiperidin-1-yl, 3-aminocyclopentyl, 3-aminomethylcyclopentyl, 3-aminomethylcyclohexyl, 3-aminohexahydroazepin-1-yl, 3-amino-cyclohexyl, piperazin-1-yl, homopiperazin-1-yl, 3-amino-pyrrolidin-1-yl, and R-3-aminopiperidin-1-yl, each unsubstituted or substituted, wherein unsubstituted means that a given moiety may consist of only hydrogen substituents through available valencies, and wherein substituted means that a given moiety may further comprise one or more non-hydrogen substituents through available valencies that are not otherwise specified by the name of the given moiety, said non-hydrogen substituents being selected from aldehyde, alicyclic, aliphatic, alkyl, alkylene, alkylidene, amide, amino, aminoalkyl, aromatic, aryl, bicycloalkyl, bicycloaryl, carbamoyl, carbocyclyl, carboxyl, carbonyl group, cycloalkyl, cycloalkylene, ester, halo, heterobicycloalkyl, heterocycloalkylene, heteroaryl, heterobicycloaryl, heterocycloalkyl, oxo, hydroxy, iminoketone, ketone, nitro, oxaalkyl, and oxoalkyl moieties; n is 1 or 2; or a pharmaceutically acceptable salt thereof. -LX is selected from the group consisting of -(CH 2)-(2-cyano)phenyl, -(CH 2)-(3-cyano)phenyl, -(CH 2)-(2-hydroxy)phenyl, -(CH 2)-(3-hydroxy)phenyl, -(CH 2)-(2-alkenyl)phenyl, -(CH 2)-(3-alkenyl)phenyl, -(CH 2)-(2-alkynyl)phenyl, -(CH 2)-(3-alkynyl)phenyl, -(CH 2)-(2-nitro)phenyl, -(CH 2)-(3-nitro)phenyl, -(CH 2)-(2-carboxy)phenyl, -(CH 2)-(3-carboxy)phenyl, -(CH 2)-(2-carboxamido)p henyl, -(CH 2)-(3-carboxamido)phenyl, -(CH 2)-(2-sulfonamido)phenyl, -(CH 2)-(3-sulfonamido)phenyl, -(CH 2)-( 2-tetrazolyl)phenyl, -(CH 2)-(3-tetrazolyl)phenyl, -(CH 2)-(2-aminomethyl)phenyl, -(CH 2)-(3-aminomethyl)phenyl, -(CH 2)-(2-amino)phenyl, -(CH 2)-(3-amino)phenyl, -(CH 2)-(2-hydroxymethyl)phenyl, -(CH 2)-(3-hydroxymethyl)phenyl, -(CH 2)-(2 -phenyl)phenyl, -(CH 2)-(3-phenyl)phenyl, -(CH 2)-(2-CONH 2)phenyl, -(CH 2)-(3-CONH 2)phenyl, -(CH 2)-(2-CONH(C 1-7) alkyl)phenyl, -(CH 2)-(3-CONH(C 1-7)alkyl)phenyl, -(CH 2)-(2-CO 2 (C 1-7)alkyl)phenyl, -(CH 2)-( 3-CO 2 (C 1-7)alkyl)phenyl, -CH 2 -NH 2, -CH 2 -OH, -CH 2 -(C 3-7)alkyl, -CH 2 -alkene, -CH 2 -alkyne, -CH 2 -CCH, -CH 2 -(C 3-7)cycloalkyl, and -CH 2 -aryl, each substituted or unsubstituted; Z is selected from the group consisting of 3-amino-piperidin-1-yl, 3-aminomethyl-pyrrolidin-1-yl, 2-aminoazetidin-1-yl, 3-aminoazetidin-1-yl, 3-amino-3-methylpiperidin-1-yl, 3-aminocyclopentyl, 3-aminomethylcyclopentyl, 3-aminomethylcyclohexyl, 3-aminohexahydroazepin-1-yl, 3-amino-cyclohexyl, piperazin-1-yl, homopiperazin-1-yl, 3-amino-pyrrolidin-1-yl, and R-3-aminopiperidin-1-yl, each unsubstituted or substituted, wherein unsubstituted means that a given moiety may consist of only hydrogen substituents through available valencies, and wherein substituted means that a given moiety may further comprise one or more non-hydrogen substituents through available valencies that are not otherwise specified by the name of the given moiety, said non-hydrogen substituents being selected from aldehyde, alicyclic, aliphatic, alkyl, alkylene, alkylidene, amide, amino, aminoalkyl, aromatic, aryl, bicycloalkyl, bicycloaryl, carbamoyl, carbocyclyl, carboxyl, carbonyl group, cycloalkyl, cycloalkylene, ester, halo, heterobicycloalkyl, heterocycloalkylene, heteroaryl, heterobicycloaryl, heterocycloalkyl, oxo, hydroxy, iminoketone, ketone, nitro, oxaalkyl, and oxoalkyl moieties; n is 1 or 2; or a pharmaceutically acceptable salt thereof.