A digital pathology scanner for large-area microscopic imaging, comprising a plurality of microscopic objectives and a plurality of digital image sensors, wherein: the microscopic objectives and the digital image sensors are equal in quantity and fixed relatively in one-to-one correspondence, so that a microscopic objective array formed by the microscopic objectives moves synchronously when a sensor array moves relative to a tissue section; the digital image sensors are sequentially distributed so as to form the sensor array; the sensor array enables images formed by the digital image sensors to be sequentially distributed without intervals in a second direction when moving in a first direction; and the first direction is perpendicular to the second direction; characterized in that: the digital image sensors in the sensor array are distributed in the zigzag pattern; the sensor array has N rows distributed in parallel at intervals in the first direction, and N is an integer greater than or equal to 3; the digital image sensors located in outermost two rows in the sensor array are equal in quantity, which is M1, while the digital image sensors located in other rows have a quantity of M2, and M1=M2+1; and two adjacent rows are respectively an N1 th row and an N2 th row in the first direction, N2=N1+1, and N1 is an integer greater than or equal to 1; when N2 is less than N, the N2 th row is offset from the N1 th row in the second direction by a distance of FoV; when N2 is equal to N, the N2 th row protrudes from the N1 th row by a distance of FoV in the second direction; and FoV is a size of the image formed by the digital image sensor in the second direction. the digital image sensors are sequentially distributed so as to form the sensor array; the sensor array enables images formed by the digital image sensors to be sequentially distributed without intervals in a second direction when moving in a first direction; and the first direction is perpendicular to the second direction; characterized in that: the digital image sensors in the sensor array are distributed in the zigzag pattern; the sensor array has N rows distributed in parallel at intervals in the first direction, and N is an integer greater than or equal to 3; the digital image sensors located in outermost two rows in the sensor array are equal in quantity, which is M1, while the digital image sensors located in other rows have a quantity of M2, and M1=M2+1; and two adjacent rows are respectively an N1 th row and an N2 th row in the first direction, N2=N1+1, and N1 is an integer greater than or equal to 1; when N2 is less than N, the N2 th row is offset from the N1 th row in the second direction by a distance of FoV; when N2 is equal to N, the N2 th row protrudes from the N1 th row by a distance of FoV in the second direction; and FoV is a size of the image formed by the digital image sensor in the second direction. the digital image sensors in the sensor array are distributed in the zigzag pattern; the sensor array has N rows distributed in parallel at intervals in the first direction, and N is an integer greater than or equal to 3; the digital image sensors located in outermost two rows in the sensor array are equal in quantity, which is M1, while the digital image sensors located in other rows have a quantity of M2, and M1=M2+1; and two adjacent rows are respectively an N1 th row and an N2 th row in the first direction, N2=N1+1, and N1 is an integer greater than or equal to 1; when N2 is less than N, the N2 th row is offset from the N1 th row in the second direction by a distance of FoV; when N2 is equal to N, the N2 th row protrudes from the N1 th row by a distance of FoV in the second direction; and FoV is a size of the image formed by the digital image sensor in the second direction.