A cardiovasculature simulator system suitable for training and testing medical devices comprising: a cardiac system module for simulating cardiac functioning of a patient having an atrium assembly for simulating blood flow through an atrium of a heart comprising a rigid outer casing sized and shaped to house a pressurized air delivery device therein and fluidly connected to a flexible, fluid filled inner chamber, said flexible, fluid filled inner chamber constructed and arranged to contract when a pressurized fluid is exerted thereupon, thereby causing said fluid stored within to be ejected out, and expand when said pressurized fluid is removed, and a ventricle assembly for simulating blood flow through a ventricle of a heart comprising an irregularly shaped, flexible ventricle assembly inner member having said fluid stored within and surrounded by a rigid ventricle assembly outer member, said ventricle assembly inner member and said rigid ventricle assembly outer member being separated by a space there between, whereby pressurized fluid inserted within said space exerts a force upon said flexible ventricle assembly inner member causing said flexible ventricle assembly inner member to eject said fluid stored within; a vasculature system module comprising at least one tubing adapted, characterized in that said tubing adapted to have a human artery or vein and fluidly connected to at least a portion of said cardiac system module; a pneumatic supply system fluidly connected to at least a portion of said atrium assembly and to at least a portion of said ventricle assembly; and a control unit comprising one or more logic chips configured to control or modify one or more operational parameters of the cardiovasculature simulator system; whereby said cardiovasculature simulator system provides an anatomically and physiologically accurate representation of a cardiovasculature system in normal or diseased states. a cardiac system module for simulating cardiac functioning of a patient having an atrium assembly for simulating blood flow through an atrium of a heart comprising a rigid outer casing sized and shaped to house a pressurized air delivery device therein and fluidly connected to a flexible, fluid filled inner chamber, said flexible, fluid filled inner chamber constructed and arranged to contract when a pressurized fluid is exerted thereupon, thereby causing said fluid stored within to be ejected out, and expand when said pressurized fluid is removed, and a ventricle assembly for simulating blood flow through a ventricle of a heart comprising an irregularly shaped, flexible ventricle assembly inner member having said fluid stored within and surrounded by a rigid ventricle assembly outer member, said ventricle assembly inner member and said rigid ventricle assembly outer member being separated by a space there between, whereby pressurized fluid inserted within said space exerts a force upon said flexible ventricle assembly inner member causing said flexible ventricle assembly inner member to eject said fluid stored within; a vasculature system module comprising at least one tubing adapted, characterized in that said tubing adapted to have a human artery or vein and fluidly connected to at least a portion of said cardiac system module; a pneumatic supply system fluidly connected to at least a portion of said atrium assembly and to at least a portion of said ventricle assembly; and a control unit comprising one or more logic chips configured to control or modify one or more operational parameters of the cardiovasculature simulator system; whereby said cardiovasculature simulator system provides an anatomically and physiologically accurate representation of a cardiovasculature system in normal or diseased states.