A tissue disease diagnosis apparatus, the apparatus comprising: control circuitry; a broad band light source arranged to output broad band light and irradiate a target area of an organ with said output broad band light; a coherent narrow band light source arranged to output a coherent monochromatic narrow band light and irradiate the target area of the organ with said output coherent monochromatic narrow band light; at least one light sensor in communication with said control circuitry, said at least one light sensor arranged to sense said broad band light after interaction with the target area and output an image of the target area responsive to said sensed broad band light; at least one light sensor array in communication with said control circuitry, said at least one light sensor array arranged to sense said coherent monochromatic narrow band light after interaction with the target area and output a signal responsive to said sensed coherent monochromatic narrow band light; a color sensor in communication with said control circuitry and arranged to sense said broad band light after interaction with the target area and output a signal responsive to said sensed broad band light; and a housing, said broad band light source, coherent narrow band light source, at least one light sensor and color sensor situated within said housing, wherein said control circuitry is arranged to: identify an abnormality in the image output by said at least one light sensor, the abnormality identification responsive to one of intensity and color of the image; determine spatial scattering of said sensed coherent monochromatic narrow band light responsive to the output signal of said at least one light sensor; determine a chromatic impact of the interaction of said output broadband light with the target area, responsive to the output signal of said color sensor; and output a tissue information signal responsive to said image abnormality identification, said determined spatial scattering and said determined chromatic impact, further wherein said housing additionally comprises a focusing mechanism in communication with said control circuitry, said control circuitry additionally configured to automatically adjust a position of an objective lens protected by a cover with reference to a mirror attachable to the cover. control circuitry; a broad band light source arranged to output broad band light and irradiate a target area of an organ with said output broad band light; a coherent narrow band light source arranged to output a coherent monochromatic narrow band light and irradiate the target area of the organ with said output coherent monochromatic narrow band light; at least one light sensor in communication with said control circuitry, said at least one light sensor arranged to sense said broad band light after interaction with the target area and output an image of the target area responsive to said sensed broad band light; at least one light sensor array in communication with said control circuitry, said at least one light sensor array arranged to sense said coherent monochromatic narrow band light after interaction with the target area and output a signal responsive to said sensed coherent monochromatic narrow band light; a color sensor in communication with said control circuitry and arranged to sense said broad band light after interaction with the target area and output a signal responsive to said sensed broad band light; and a housing, said broad band light source, coherent narrow band light source, at least one light sensor and color sensor situated within said housing, wherein said control circuitry is arranged to: identify an abnormality in the image output by said at least one light sensor, the abnormality identification responsive to one of intensity and color of the image; determine spatial scattering of said sensed coherent monochromatic narrow band light responsive to the output signal of said at least one light sensor; determine a chromatic impact of the interaction of said output broadband light with the target area, responsive to the output signal of said color sensor; and output a tissue information signal responsive to said image abnormality identification, said determined spatial scattering and said determined chromatic impact, identify an abnormality in the image output by said at least one light sensor, the abnormality identification responsive to one of intensity and color of the image; determine spatial scattering of said sensed coherent monochromatic narrow band light responsive to the output signal of said at least one light sensor; determine a chromatic impact of the interaction of said output broadband light with the target area, responsive to the output signal of said color sensor; and output a tissue information signal responsive to said image abnormality identification, said determined spatial scattering and said determined chromatic impact, further wherein said housing additionally comprises a focusing mechanism in communication with said control circuitry, said control circuitry additionally configured to automatically adjust a position of an objective lens protected by a cover with reference to a mirror attachable to the cover.