An electrophoretic notch filter apparatus comprising: a. a gel cartridge including at least one sample channel, each sample channel including a cathode buffer chamber with an aperture, a sample introduction chamber, wherein each sample introduction chamber includes an aperture that passes through the sample introduction chamber and is associated at one end with the aperture of the cathode buffer chamber, a tube gel including a first end associated with the sample introduction chamber, a sample collection chamber associated with a second end of the tube gel and an anode buffer chamber, wherein the sample collection chamber is included in a sample collection housing, including apertures that are associated with an aperture in the anode buffer chamber and wherein the cathode buffer chamber, the sample introduction chamber, the gel tube, the sample collection chamber and the anode buffer chamber are capable of ionic electrical contact, wherein the cross section of the tube gel is between 0.1 mm and 10 mm, and wherein the internal and outer diameter of the tube does not vary significantly from tube to tube; b. a power supply that is engagable with a cathode buffer chamber of each sample channel and anode buffer chamber of each sample channel; c. a user interface for programming one or more steps for a sample channel into a processor wherein programming a step includes programming at least one of a current or voltage that is applied across the sample channel during the programmed step and programming the duration of the application of the voltage or current across the sample channel wherein the programmed one or more steps form a programmed sequence, and wherein the pre-programmed voltage to be applied is from 1-300V; and d. an electrophoretic controller including the processor for implementing the programmed sequence. a. a gel cartridge including at least one sample channel, each sample channel including a cathode buffer chamber with an aperture, a sample introduction chamber, wherein each sample introduction chamber includes an aperture that passes through the sample introduction chamber and is associated at one end with the aperture of the cathode buffer chamber, a tube gel including a first end associated with the sample introduction chamber, a sample collection chamber associated with a second end of the tube gel and an anode buffer chamber, wherein the sample collection chamber is included in a sample collection housing, including apertures that are associated with an aperture in the anode buffer chamber and wherein the cathode buffer chamber, the sample introduction chamber, the gel tube, the sample collection chamber and the anode buffer chamber are capable of ionic electrical contact, wherein the cross section of the tube gel is between 0.1 mm and 10 mm, and wherein the internal and outer diameter of the tube does not vary significantly from tube to tube; b. a power supply that is engagable with a cathode buffer chamber of each sample channel and anode buffer chamber of each sample channel; c. a user interface for programming one or more steps for a sample channel into a processor wherein programming a step includes programming at least one of a current or voltage that is applied across the sample channel during the programmed step and programming the duration of the application of the voltage or current across the sample channel wherein the programmed one or more steps form a programmed sequence, and wherein the pre-programmed voltage to be applied is from 1-300V; and d. an electrophoretic controller including the processor for implementing the programmed sequence.