17-Hydroxy-17-pentafluoroethyl-estra-4,9 -dien-11-aryl derivates of the general formula I in which R 1 and R 2 are identical or different and are hydrogen, an optionally dimethylamine-substituted C 1 -C 10 -alkyl radical, a 6-10-membered aryl radical optionally mono-, di- or polysubstituted with halogen (-F, -Cl, -Br, -I), -OH, -0-alkyl, -C OH, -C Oalkyl, -C NH 2, -C NHalkyl, -C Ndialkyl, -C NHaryl, -C NHheteroaryl, -NH 2, -NH (C 1 -C 10 -alkyl), -N(C 1 -C 10 -alkyl) 2, in particular -N(CH 3) 2, -NHC alkyl, -NO 2, -N 3, -CN, -C 1 -C 10 -alkyl, -C 1 -C 10 -perfluoroalkyl, -C 1 -C 10 -acyl, -C 1 -C 10 -acyloxy, -SO 2 NH 2, -SO 2 NHalkyl or -SO 2 Ndialkyl, a 5-10-membered heteroaryl radical optionally mono-, di- or polysubstituted with the aforementioned substituents of the 6-10-membered aryl radical, a C 1 -C 6 -arylalkyl radical optionally mono-, di- or polysubstituted on the aryl ring with the aforementioned substituents of the 6-10-membered aryl radical or a C 1 -C 6 -heteroarylalkyl radical optionally mono-, di- or polysubstituted on the heteroaryl ring with the aforementioned substituents of the 6-10-membered aryl radical, or else R 1 and R 2 are together a constituent of a 3-10-membered ring which is optionally substituted on the carbon by alkyl, carboxyl, alkoxycarbonyl, alkylcarbonyl, aminocarbonyl, arylalkyl, heteroarylalkyl, aminoalkyl and/or on the nitrogen by alkyl, alkanoyl, carboxyl, alkoxycarbonyl, phenyl, phenylalkyl, pyridinyl, pyrimidinyl, pyrazinyl, sulphonyl, benzoyl, alkylsulphonyl, arylsulphonyl, aminocarbonyl, aminocarbonylalkyl, arylalkyl, heteroarylalkyl, heterocyclylalkyl and aminoalkyl, and which optionally contains nitrogen, oxygen or sulphur atoms which can optionally be oxidized with the sulphoxide or sulphone, where an aromatic can optionally be fused onto the 3-10-membered ring, X is an oxygen atom or NOR 3 or NNHSO 2 R 3, R 3 is selected from the group comprising hydrogen, C 1 -C 10 -alkyl, aryl and their salts, solvates or solvates of the salts, including all crystal modifications. R 1 and R 2 are identical or different and are hydrogen, an optionally dimethylamine-substituted C 1 -C 10 -alkyl radical, a 6-10-membered aryl radical optionally mono-, di- or polysubstituted with halogen (-F, -Cl, -Br, -I), -OH, -0-alkyl, -C OH, -C Oalkyl, -C NH 2, -C NHalkyl, -C Ndialkyl, -C NHaryl, -C NHheteroaryl, -NH 2, -NH (C 1 -C 10 -alkyl), -N(C 1 -C 10 -alkyl) 2, in particular -N(CH 3) 2, -NHC alkyl, -NO 2, -N 3, -CN, -C 1 -C 10 -alkyl, -C 1 -C 10 -perfluoroalkyl, -C 1 -C 10 -acyl, -C 1 -C 10 -acyloxy, -SO 2 NH 2, -SO 2 NHalkyl or -SO 2 Ndialkyl, a 5-10-membered heteroaryl radical optionally mono-, di- or polysubstituted with the aforementioned substituents of the 6-10-membered aryl radical, a C 1 -C 6 -arylalkyl radical optionally mono-, di- or polysubstituted on the aryl ring with the aforementioned substituents of the 6-10-membered aryl radical or a C 1 -C 6 -heteroarylalkyl radical optionally mono-, di- or polysubstituted on the heteroaryl ring with the aforementioned substituents of the 6-10-membered aryl radical, or else R 1 and R 2 are together a constituent of a 3-10-membered ring which is optionally substituted on the carbon by alkyl, carboxyl, alkoxycarbonyl, alkylcarbonyl, aminocarbonyl, arylalkyl, heteroarylalkyl, aminoalkyl and/or on the nitrogen by alkyl, alkanoyl, carboxyl, alkoxycarbonyl, phenyl, phenylalkyl, pyridinyl, pyrimidinyl, pyrazinyl, sulphonyl, benzoyl, alkylsulphonyl, arylsulphonyl, aminocarbonyl, aminocarbonylalkyl, arylalkyl, heteroarylalkyl, heterocyclylalkyl and aminoalkyl, and which optionally contains nitrogen, oxygen or sulphur atoms which can optionally be oxidized with the sulphoxide or sulphone, where an aromatic can optionally be fused onto the 3-10-membered ring, X is an oxygen atom or NOR 3 or NNHSO 2 R 3, R 3 is selected from the group comprising hydrogen, C 1 -C 10 -alkyl, aryl