Compounds of the formula I in which R denotes H, OH, A or NR 4 R 4', R 1 denotes Ar 1, Het 1, CN, A or -C≡C-Ar 1, R 2 denotes Het 2, NR 3 Cyc, NR 3 CR 3 CON(R 3) 2, NR 3 [C(R 3) 2]pCR 3 (NH 2)CH 2 OA or NR 3 [C(R 3) 2] p N(R 3) 2, Ar 1 denotes phenyl, which is mono-, di- or trisubstituted by A, (CH 2) n Het 3, [C(R 3) 2] n OR 3, [C(R 3) 2] n N(R 3) 2, NO 2, CN, Hal, COOR 3, CON(R 3) 2, NR 3 COA, NR 3 SO 2 A, SO 2 N(R 3) 2 and/or S m A, Het 1 denotes 3,6-dihydro-2H-pyranyl, tetrahydropyridinyl, 1,3-dihydro-benzimidazolyl, pyrazolyl, chromanyl, 1,2,3,4-tetrahydro-pyrazolo[1,5-a]pyridinyl, 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]-oxazinyl, 1,4-dihydro-benzo[d][1,3]-oxazinyl, 4H-benzo[1,4]oxazinyl, benzimidazolyl, pyridyl, pyrimidinyl, imidazolyl, pyrazolyl, furyl, thiazolyl, triazolyl, benzotriazolyl, indolyl, indazolyl, 1,3- or 2,3-dihydro-indolyl, each of which is unsubstituted or mono-, di-, tri- or tetrasubstituted by A, CN, OH, OA, Hal, SO 2 NH 2, (CH 2) n NH 2, (CH 2) n NHA, (CH 2) n NA 2 and/or =O, Het 2 denotes piperidinyl, piperazinyl, pyrrolidinyl, morpholinyl, tetrahydropyranyl, pyrazolyl, indazolyl, azetidinyl or octahydro-benzimidazolyl, each of which is mono-, di- or trisubstituted by Hal, A, (CH 2) n NH 2, (CH 2) n NHA, (CH 2) n NA 2, (CH 2) n OH and/or (CH 2) n OA, Het 3 denotes piperidinyl, piperazinyl, pyrrolidinyl, morpholinyl, imidazolidinyl, pyridyl, pyrimidinyl, imidazolyl, pyrazolyl, furyl, thiazolyl or triazolyl, each of which is unsubstituted or mono- or disubstituted by A and/or =O, R 3 denotes H or alkyl having 1, 2, 3 or 4 C-atoms, R 4, R 4' each, independently of one another, denote H or A, A denotes unbranched or branched alkyl having 1-10 C atoms, in which 1-7 H atoms may be replaced by F and/or in which one or two non-adjacent CH 2 groups may be replaced by O and/or NH, or cyclic alkyl having 3-7 C atoms, Cyc denotes cyclic alkyl having 3-7 C atoms, which may be unsubstituted or monosubstituted by NH 2, CN, CONH 2 or OH, m denotes 0, 1 or 2, n denotes 0, 1, 2, 3 or 4, p denotes 1, 2, 3 or 4, and pharmaceutically acceptable solvates, salts, enantiomers, tautomers and stereoisomers thereof, including mixtures thereof in all ratios. R denotes H, OH, A or NR 4 R 4', R 1 denotes Ar 1, Het 1, CN, A or -C≡C-Ar 1, R 2 denotes Het 2, NR 3 Cyc, NR 3 CR 3 CON(R 3) 2, NR 3 [C(R 3) 2]pCR 3 (NH 2)CH 2 OA or NR 3 [C(R 3) 2] p N(R 3) 2, Ar 1 denotes phenyl, which is mono-, di- or trisubstituted by A, (CH 2) n Het 3, [C(R 3) 2] n OR 3, [C(R 3) 2] n N(R 3) 2, NO 2, CN, Hal, COOR 3, CON(R 3) 2, NR 3 COA, NR 3 SO 2 A, SO 2 N(R 3) 2 and/or S m A, Het 1 denotes 3,6-dihydro-2H-pyranyl, tetrahydropyridinyl, 1,3-dihydro-benzimidazolyl, pyrazolyl, chromanyl, 1,2,3,4-tetrahydro-pyrazolo[1,5-a]pyridinyl, 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]-oxazinyl, 1,4-dihydro-benzo[d][1,3]-oxazinyl, 4H-benzo[1,4]oxazinyl, benzimidazolyl, pyridyl, pyrimidinyl, imidazolyl, pyrazolyl, furyl, thiazolyl, triazolyl, benzotriazolyl, indolyl, indazolyl, 1,3- or 2,3-dihydro-indolyl, each of which is unsubstituted or mono-, di-, tri- or tetrasubstituted by A, CN, OH, OA, Hal, SO 2 NH 2, (CH 2) n NH 2, (CH 2) n NHA, (CH 2) n NA 2 and/or =O, Het 2 denotes piperidinyl, piperazinyl, pyrrolidinyl, morpholinyl, tetrahydropyranyl, pyrazolyl, indazolyl, azetidinyl or octahydro-benzimidazolyl, each of which is mono-, di- or trisubstituted by Hal, A, (CH 2) n NH 2, (CH 2) n NHA, (CH 2) n NA 2, (CH 2) n OH and/or (CH 2) n OA, Het 3 denotes piperidinyl, piperazinyl, pyrrolidinyl, morpholinyl, imidazolidinyl, pyridyl, pyrimidinyl, imidazolyl, pyrazolyl, furyl, thiazolyl or triazolyl, each of which is unsubstituted or mono- or disubstituted by A and/or =O, R 3 denotes H or alkyl having 1, 2, 3 or 4 C-atoms, R 4, R 4' each, independently of one another, denote H or A, A denotes unbranched or branched alkyl having 1-10 C atoms, in which 1-7 H atoms may be replaced by F and/or in which one or two non-adjacent CH 2 groups may be replaced by O and/or NH, or cyclic alkyl having 3-7 C atoms, Cyc denotes cyclic alkyl having 3-7 C atoms, which may be unsubstituted or monosubstituted by NH 2, CN, CONH 2 or OH, m denotes 0, 1 or 2, n denotes 0, 1, 2, 3 or 4, p denotes 1, 2, 3 or 4,