mhurhangee/ep-ind-claims huggingface dataset:
In vitro process for determining the functional IL-17 pro-inflammatory dependent level (IPDL) of a biological sample chosen from whole blood, plasma and serum, comprising the following steps: a) measuring the level of an inflammatory marker produced by IL-17-sensitive cells incubated in the presence of said biological sample, said IL-17-sensitive cells being endothelial cells, b) measuring the level of said inflammatory marker produced by said endothelial cells incubated in the presence of said biological sample, in the presence of antibodies which neutralize the biological activity of IL-17, and c) determining the IPDL value, which is the difference between the level of said inflammatory marker measured in step a) and the level of said inflammatory marker measured in step b). a) measuring the level of an inflammatory marker produced by IL-17-sensitive cells incubated in the presence of said biological sample, said IL-17-sensitive cells being endothelial cells, b) measuring the level of said inflammatory marker produced by said endothelial cells incubated in the presence of said biological sample, in the presence of antibodies which neutralize the biological activity of IL-17, and c) determining the IPDL value, which is the difference between the level of said inflammatory marker measured in step a) and the level of said inflammatory marker measured in step b).
A drug delivery device comprising: a housing including: a lower body, the lower body defining a lower body channel, an upper body, the upper body defining an upper body channel, and a ring member, the ring member extending upward from an annular step surface of the lower body toward a housing upper end; and a drug cartridge defining a depot channel, the ring member including indicia indicating a characteristic of one or more drug depots in the drug cartridge; wherein the drug cartridge comprises a first plate having the depot channel, the depot channel capable of storing the one or more drug depots, characterized in that the first plate is in one piece with a funnel body comprising alignment ridges mating with alignment grooves in piers of the housing to align the drug cartridge with the housing. a housing including: a lower body, the lower body defining a lower body channel, an upper body, the upper body defining an upper body channel, and a ring member, the ring member extending upward from an annular step surface of the lower body toward a housing upper end; and a lower body, the lower body defining a lower body channel, an upper body, the upper body defining an upper body channel, and a ring member, the ring member extending upward from an annular step surface of the lower body toward a housing upper end; and a drug cartridge defining a depot channel, the ring member including indicia indicating a characteristic of one or more drug depots in the drug cartridge;
A battery state estimation device, comprising: a current detector configured to detect as a current measured value, a current of a secondary battery; a voltage detector configured to detect as a voltage measured value, a terminal voltage of the secondary battery; a state variable filter operator configured to define a battery model of the secondary battery, wherein by using a state variable filter which is based on the battery model, the state variable filter operator subjects to a state quantity conversion the current measured value and the voltage measured value to thereby calculate a conversion state quantity, and from the conversion state quantity, the state variable filter operator estimates, as a voltage estimated value, the terminal voltage of the secondary battery which terminal voltage is based on the battery model; and an adaptive identification operator configured to identify a parameter of the secondary battery such that a difference between the voltage measured value and the voltage estimated value is converged to zero, characterized in that the adaptive identification operator is configured to subject the voltage measured value and the voltage estimated value to a filter treatment by a low pass filter (Glpf) having a common high frequency breaking characteristic and to calculate the difference by using the voltage measured value and the voltage estimated value which are subjected to the filter treatment by the low pass filter (Glpf). a current detector configured to detect as a current measured value, a current of a secondary battery; a voltage detector configured to detect as a voltage measured value, a terminal voltage of the secondary battery; a state variable filter operator configured to define a battery model of the secondary battery, wherein by using a state variable filter which is based on the battery model, the state variable filter operator subjects to a state quantity conversion the current measured value and the voltage measured value to thereby calculate a conversion state quantity, and from the conversion state quantity, the state variable filter operator estimates, as a voltage estimated value, the terminal voltage of the secondary battery which terminal voltage is based on the battery model; and an adaptive identification operator configured to identify a parameter of the secondary battery such that a difference between the voltage measured value and the voltage estimated value is converged to zero, characterized in that the adaptive identification operator is configured to subject the voltage measured value and the voltage estimated value to a filter treatment by a low pass filter (Glpf) having a common high frequency breaking characteristic and to calculate the difference by using the voltage measured value and the voltage estimated value which are subjected to the filter treatment by the low pass filter (Glpf).
Assembly for a control device, in particular of an exhaust gas turbo-charger, - having a housing part, - having a shaft which is supported rotationally on the housing part by means of a bearing means formed separately from the housing part, - having a magnetic field sensor mounted on the housing part, which interacts with a magnet element mounted non-rotationally on the shaft to determine a rotational angle position of the shaft relatively to the housing part, - wherein the bearing element is accommodated in a housing wall portion of the housing part formed complementarily to the bearing element, characterised in that - on the end face of the shaft facing the magnetic field sensor is formed a recess in which the magnet element is at least partially, preferably completely, accommodated, - the housing wall portion is formed as a web with annular-segment-shaped geometry which partially encloses the bearing element on the outside. - having a housing part, - having a shaft which is supported rotationally on the housing part by means of a bearing means formed separately from the housing part, - having a magnetic field sensor mounted on the housing part, which interacts with a magnet element mounted non-rotationally on the shaft to determine a rotational angle position of the shaft relatively to the housing part, - wherein the bearing element is accommodated in a housing wall portion of the housing part formed complementarily to the bearing element, characterised in that - on the end face of the shaft facing the magnetic field sensor is formed a recess in which the magnet element is at least partially, preferably completely, accommodated, - the housing wall portion is formed as a web with annular-segment-shaped geometry which partially encloses the bearing element on the outside.
A method for producing a polyhydric phenol from 2-deoxy-scyllo-inosose, comprising the following steps (a) to (d): (a) a first step of producing a compound represented by the following formula from 2-deoxy-scyllo-inosose by a dehydration reaction; (b) a second step of producing 1, 2, 4-trihydroxybenzene from the compound represented by said formula obtained in said first step by a dehydration reaction; (c) a third step of producing 4-hydroxycyclohexane-1, 3-dione or a salt thereof from the 1,2,4-trihydroxybenzene by a catalytic hydrogenation reaction with the use of a metal catalyst; and (d) a fourth step of producing hydroquinone by heating the 4-hydroxycyclohexane-1,3-dione or the salt thereof. (a) a first step of producing a compound represented by the following formula from 2-deoxy-scyllo-inosose by a dehydration reaction; (b) a second step of producing 1, 2, 4-trihydroxybenzene from the compound represented by said formula obtained in said first step by a dehydration reaction; (c) a third step of producing 4-hydroxycyclohexane-1, 3-dione or a salt thereof from the 1,2,4-trihydroxybenzene by a catalytic hydrogenation reaction with the use of a metal catalyst; and (d) a fourth step of producing hydroquinone by heating the 4-hydroxycyclohexane-1,3-dione or the salt thereof.
Pre-stretching roller of an unwinding apparatus associable to a wrapping machine, comprising a main body elongated along a longitudinal central axis and manufactured by an extrusion process, in particular of a metal alloy, and including: - a first tubular element having a cylindrical shape and defining an external cylindrical wall suitable for interacting with a film; - a second tubular element internal to said first tubular element and having a first end provided with a first seat suitable for receiving and coupling with a driving shaft (31; 41) of driving means (35; 45) of said unwinding apparatus and an opposite second end provided with a second seat suitable for receiving and coupling with a supporting pin for fixing said pre-stretching roller to said unwinding apparatus; - a plurality of longitudinal vanes, parallel to said central axis and which connect said first tubular element to said second tubular element; characterised in that said second tubular element comprises a plurality of longitudinal ribs, in particular parallel to said central axis, each longitudinal rib being connected to a respective longitudinal vane. - a first tubular element having a cylindrical shape and defining an external cylindrical wall suitable for interacting with a film; - a second tubular element internal to said first tubular element and having a first end provided with a first seat suitable for receiving and coupling with a driving shaft (31; 41) of driving means (35; 45) of said unwinding apparatus and an opposite second end provided with a second seat suitable for receiving and coupling with a supporting pin for fixing said pre-stretching roller to said unwinding apparatus; - a plurality of longitudinal vanes, parallel to said central axis and which connect said first tubular element to said second tubular element;
A suture anchor for securing soft tissue to bone comprising: an outer member including a body having an inner cavity, the inner cavity including a proximal portion configured for receipt of a delivery device and a distal portion having an area of increased diameter; and an inner member coupled to the outer member, the inner member including a proximal portion having a projection configured for receipt in the area of increased diameter such that the outer member is rotatable relative to the inner member; and a distal portion having a transverse through hole, wherein the outer member includes threads on an outer surface. an outer member including a body having an inner cavity, the inner cavity including a proximal portion configured for receipt of a delivery device and a distal portion having an area of increased diameter; and an inner member coupled to the outer member, the inner member including a proximal portion having a projection configured for receipt in the area of increased diameter such that the outer member is rotatable relative to the inner member; and a distal portion having a transverse through hole, wherein the outer member includes threads on an outer surface.
A rotating connector formed within an endoscope console for connecting an endoscope to a console, comprising: at least one fixed part located on the endoscope console for attaching the rotating connector to the console; and a rotating part adapted to be attached to the at least one fixed part such that the rotating part can rotate relatively to the at least one fixed part, the rotating part also adapted to receiving an endoscope connector, wherein the rotating connector enables rotation of the endoscope while essentially eliminating or reducing twisting of a proximal shaft connected to the endoscope, wherein the at least one fixed part comprises a recess and the at least one rotating part comprises a protruding part so that movement of the moving part within the recess limits the rotation of the at least one rotating part, characterized in that the rotation of the at least one rotating part is limited to about 90° and in that the at least one fixed part comprises a disk, the disk comprising a recess for containing gas, fluid or liquid over flow, and a gasket for sealing a gap between the disk and the at least one rotating part. at least one fixed part located on the endoscope console for attaching the rotating connector to the console; and a rotating part adapted to be attached to the at least one fixed part such that the rotating part can rotate relatively to the at least one fixed part, the rotating part also adapted to receiving an endoscope connector, wherein the rotating connector enables rotation of the endoscope while essentially eliminating or reducing twisting of a proximal shaft connected to the endoscope,
A method for producing an annular casing for an aircraft turbine engine, this casing comprising an annular body made from a composite material based on a first resin, and a fire-resistant external layer which covers an external annular surface of the body and which is made from a composite material based on a self-extinguishing second resin, such that it comprises: a) a step of preparing a strip of a fabric pre-impregnated with said second resin, this strip having an elongated shape along an axis of elongation and a width (l) at least equal to and preferably greater than a width of said body measured along its axis of revolution, this strip comprising fibres woven and oriented in directions perpendicular to one another and inclined by an angle of about 45° with respect to said axis of elongation; and b) a step of applying the strip on the external surface of the body, so as to cover the entirety of this surface in a single pass of the strip around the body. a) a step of preparing a strip of a fabric pre-impregnated with said second resin, this strip having an elongated shape along an axis of elongation and a width (l) at least equal to and preferably greater than a width of said body measured along its axis of revolution, this strip comprising fibres woven and oriented in directions perpendicular to one another and inclined by an angle of about 45° with respect to said axis of elongation; and b) a step of applying the strip on the external surface of the body, so as to cover the entirety of this surface in a single pass of the strip around the body.
A cardioplegic composition for reperfusion of a procured donor heart comprising: 300 μmol/L to 450 μmol/L of adenosine; 40 μmol/L to 90 μmol/L of lidocaine; 8.0 mmol/L to 12.5 mmol/L of glucose; 120 to 140 mmol/L of NaCl; 4.0 mmol/L to 7.0 mmol/L of KCI; 12.0 mmol/L to 16.0 mmol/L of NaHCO 3; 0.9 mmol/L to 1.4 mmol/L of NaH 2 PO 4; 0.18 mmol/L to 0.26 mmol/L of CaCl 2; 11.0 to 15.0 mmol/L of MgCl 2; 7.5 IU/L to 12.5 IU/L of insulin; 100.0 mmol/L to 140.0 mmol/L of D-mannitol; 0.75 mmol/L to 1.25 mmol/L of pyruvate; and 2.5 mmol/L to 3.5 mmol/L of reduced glutathione, wherein the composition has a pH of 6.6 to 6.9. 300 μmol/L to 450 μmol/L of adenosine; 40 μmol/L to 90 μmol/L of lidocaine; 8.0 mmol/L to 12.5 mmol/L of glucose; 120 to 140 mmol/L of NaCl; 4.0 mmol/L to 7.0 mmol/L of KCI; 12.0 mmol/L to 16.0 mmol/L of NaHCO 3; 0.9 mmol/L to 1.4 mmol/L of NaH 2 PO 4; 0.18 mmol/L to 0.26 mmol/L of CaCl 2; 11.0 to 15.0 mmol/L of MgCl 2; 7.5 IU/L to 12.5 IU/L of insulin; 100.0 mmol/L to 140.0 mmol/L of D-mannitol; 0.75 mmol/L to 1.25 mmol/L of pyruvate; and 2.5 mmol/L to 3.5 mmol/L of reduced glutathione, wherein the composition has a pH of 6.6 to 6.9.
A method, comprising the steps: blending a polymeric composition, comprising: (a) 5 wt% to 45 wt% of a silanol-functionalized polyolefin based on a total weight of the polymeric composition; (b) 50 wt% to 90 wt% of a polybutylene terephthalate based on a total weight of the polymeric composition having a melt flow index from 21 g/10 min. to 35 g/10 min. at 250°C and 2.16 kg, as measured according to ASTM method D1238; (c) a condensation catalyst; and (d) 0.5 wt% to 10 wt% of hydroxy terminated poly(dimethylsiloxane) based on a total weight of the polymeric composition; and extruding the polymeric composition; wherein the blending step further comprises blending 0.1 wt% to 10 wt% maleated ethylene-based polymer into the polymeric composition based on a total weight of the polymeric composition. blending a polymeric composition, comprising: (a) 5 wt% to 45 wt% of a silanol-functionalized polyolefin based on a total weight of the polymeric composition; (b) 50 wt% to 90 wt% of a polybutylene terephthalate based on a total weight of the polymeric composition having a melt flow index from 21 g/10 min. to 35 g/10 min. at 250°C and 2.16 kg, as measured according to ASTM method D1238; (c) a condensation catalyst; and (d) 0.5 wt% to 10 wt% of hydroxy terminated poly(dimethylsiloxane) based on a total weight of the polymeric composition; and (a) 5 wt% to 45 wt% of a silanol-functionalized polyolefin based on a total weight of the polymeric composition; (b) 50 wt% to 90 wt% of a polybutylene terephthalate based on a total weight of the polymeric composition having a melt flow index from 21 g/10 min. to 35 g/10 min. at 250°C and 2.16 kg, as measured according to ASTM method D1238; (c) a condensation catalyst; and (d) 0.5 wt% to 10 wt% of hydroxy terminated poly(dimethylsiloxane) based on a total weight of the polymeric composition; and extruding the polymeric composition; wherein the blending step further comprises blending 0.1 wt% to 10 wt% maleated ethylene-based polymer into the polymeric composition based on a total weight of the polymeric composition.
A sampling device for sampling a biological molecule from a subject, the sampling device comprising a surface-functionalised silica xerogel, wherein the surface-functionalised silica xerogel comprises a functional group capable of selectively binding to the biological molecule in a biological fluid from the subject, wherein the surface-functionalised silica xerogel is monolithic and for insertion into a body orifice, body cavity or bodily tube to sample the biological molecule from the subject.
A method of determining the melting temperature of a duplex nucleic acid molecule, said method comprising subjecting a solution comprising a double-stranded nucleic acid molecule to a square wave temperature gradient, said gradient comprising a range of temperatures that causes at least one transition of said double-stranded nucleic acid molecule to single-stranded nucleic acid molecules, said gradient comprising a series of temperature pulses, each pulse comprising: a) increasing the temperature of said solution to a first high temperature; b) decreasing the temperature of said solution to a second low temperature; wherein said first high temperature is greater than said second low temperature; and wherein, in subsequent pulses, said first high temperature and said second low temperature are each adjusted to be greater than the first and second temperatures, respectively, in prior pulses; and detecting said at least one transition over the course of said square wave temperature gradient. a) increasing the temperature of said solution to a first high temperature; b) decreasing the temperature of said solution to a second low temperature; wherein said first high temperature is greater than said second low temperature; and wherein, in subsequent pulses, said first high temperature and said second low temperature are each adjusted to be greater than the first and second temperatures, respectively, in prior pulses; and
Method for the manufacture of a coated steel sheet comprising the following successive steps: A. the coating of the steel sheet with a first coating consisting of nickel and having a thickness between 750 nm and 950nm, the steel sheet having the following composition in weight: 0.10 < C < 0.40 %, 1.5 < Mn < 3.0 %, 0.7 < Si < 3.0 %, 0.05 < Al < 1.0 %, 0.75 < Si + Al < 3.0 %, and on a purely optional basis, one or more elements such as Nb ≤ 0.5 %, B ≤ 0.010%, Cr ≤ 1.0%, Mo ≤ 0.50%, Ni ≤ 1.0%, Ti ≤ 0.5%, the remainder of the composition making up of iron and inevitable impurities resulting from the elaboration, B. the recrystallization annealing of said coated steel sheet at a temperature between 820 to 1200°C, performed in an atmosphere comprising from 1 to 10% of H 2 at a dew point between -30 and +30°C, C. the coating of the steel sheet obtained in step B) with a second coating based on zinc not comprising nickel. A. the coating of the steel sheet with a first coating consisting of nickel and having a thickness between 750 nm and 950nm, the steel sheet having the following composition in weight: 0.10 < C < 0.40 %, 1.5 < Mn < 3.0 %, 0.7 < Si < 3.0 %, 0.05 < Al < 1.0 %, 0.75 < Si + Al < 3.0 %, and on a purely optional basis, one or more elements such as Nb ≤ 0.5 %, B ≤ 0.010%, Cr ≤ 1.0%, Mo ≤ 0.50%, Ni ≤ 1.0%, Ti ≤ 0.5%, the remainder of the composition making up of iron and inevitable impurities resulting from the elaboration, B. the recrystallization annealing of said coated steel sheet at a temperature between 820 to 1200°C, performed in an atmosphere comprising from 1 to 10% of H 2 at a dew point between -30 and +30°C, C. the coating of the steel sheet obtained in step B) with a second coating based on zinc not comprising nickel.
Device for illumination of at least one display indicator of a timepiece or scientific apparatus, said indicator being incorporated in a case comprised in said device under an aperture also comprised in said device, said device including at least one phosphorescent light source in said case, means for collecting external light energy from the ambient medium of said case towards said phosphorescent light source, and in said device is arranged a light component, formed either by said phosphorescent light source, or by a light relay connected to said phosphorescent light source by means for transmission of the light energy re-transmitted by said phosphorescent light source, to illuminate said indicator, either on the side opposite to said aperture with respect to said indicator, or at the periphery of said aperture, characterized in that said device includes a cover that can be inserted between said light component and said indicator between a blanking position where said cover blocks the passage of light between said light component and said indicator, and a lighting position where said cover does not obstruct the passage of light and a control means arranged to move said cover, and in that said cover is made of opaque material with an aesthetic function in day mode, and enhancing contrast in the reading of said indicator.