mhurhangee/ep-ind-claims huggingface dataset:
Conduit for a liquid dispenser, including: a tube for carrying liquid; and a heating device for heating at least a section of the tube, wherein the heating device includes a part for fixing the heating device to the tube, and the part is a part injection-moulded over the tube along at least a section of a length of the tube, wherein the heating device includes a resistive heating part, which resistive heating part includes a wound heating wire, characterised in that the conduit further includes a carrier, wherein the heating wire is wound around the carrier and the carrier is arranged between the tube and the injection-moulded part. a tube for carrying liquid; and a heating device for heating at least a section of the tube, wherein the heating device includes a part for fixing the heating device to the tube, and the part is a part injection-moulded over the tube along at least a section of a length of the tube, wherein the heating device includes a resistive heating part, which resistive heating part includes a wound heating wire, characterised in that the conduit further includes a carrier, wherein the heating wire is wound around the carrier and the carrier is arranged between the tube and the injection-moulded part.
A human natural killer cell or NK cell line with increased cytotoxicity for use in treating cancer cells in a patient, wherein the NK cell or NK cell line has been modified by genetic engineering to express a TRAIL variant, wherein the TRAIL variant has an increased affinity, with respect to wildtype TRAIL, for TRAIL receptors, and wherein the NK cell or NK cell line has been further modified to express one or more chimeric antigen receptors (CARs), wherein the CARs specifically bind to one or more ligands on the cancer cells.
A device for measuring viscoelastic properties of a viscoelastic medium having an ultrasound signal after being subjected to ultrasound pulses comprising: - a probe for vibration controlled transient elastography comprising: • a probe casing; • at least one ultrasound transducer having a symmetry axis; • at least a vibrator, said vibrator being located inside the probe casing; • a force sensor, the force sensor being configured to measure a force applied by the probe against the to-be-measured viscoelastic medium; - a signal generator; the device being characterized in that: • the vibrator is arranged to induce a movement of the probe casing along a predefined axis, the predefined axis being the symmetry axis of the ultrasound transducer; • the ultrasound transducer is bound to the probe casing with no motion of the ultrasound transducer with respect to the probe casing; • the signal generator is constructed and arranged to issue a contact ready signal when the ultrasound transducer of the probe is in contact with a to-be-measured viscoelastic medium, the contact ready signal being set by the signal generator when the force applied by the ultrasound probe on the viscoelastic medium is greater than a minimum contact force threshold. - a probe for vibration controlled transient elastography comprising: • a probe casing; • at least one ultrasound transducer having a symmetry axis; • at least a vibrator, said vibrator being located inside the probe casing; • a force sensor, the force sensor being configured to measure a force applied by the probe against the to-be-measured viscoelastic medium; • a probe casing; • at least one ultrasound transducer having a symmetry axis; • at least a vibrator, said vibrator being located inside the probe casing; • a force sensor, the force sensor being configured to measure a force applied by the probe against the to-be-measured viscoelastic medium; - a signal generator; • the vibrator is arranged to induce a movement of the probe casing along a predefined axis, the predefined axis being the symmetry axis of the ultrasound transducer; • the ultrasound transducer is bound to the probe casing with no motion of the ultrasound transducer with respect to the probe casing; • the signal generator is constructed and arranged to issue a contact ready signal when the ultrasound transducer of the probe is in contact with a to-be-measured viscoelastic medium, the contact ready signal being set by the signal generator when the force applied by the ultrasound probe on the viscoelastic medium is greater than a minimum contact force threshold.
A microfluidic device comprising: a first porous substrate; a plurality of reaction channels disposed on a first side of the first porous substrate, the reaction channels defined by a barrier material disposed on a surface of the substrate in a user-defined pattern; and at least one reagent disposed within each reaction channel providing a colorimetric analysis of at least one analyte or property in a sample introduced to the device, wherein the first porous substrate is disposed within a housing, said housing comprising a first backing and a second backing, the first porous substrate being disposed between the first backing and the second backing, characterized in that the first backing comprises a first centrally located aperture defining a single sample port from which the sample travels radially outward to each of the reaction channels by capillary action and a plurality of second apertures positioned over corresponding reaction channels and, below the second backing, a second porous substrate and third backing, said second porous substrate having a plurality of reaction channels disposed on a first side thereof, and said third backing comprising a plurality of second apertures defining vents, wherein the reaction channels disposed on the first side of the first porous substrate provide one set of test results and the reaction channels disposed on the first side of the second porous substrate provide another set of results. a first porous substrate; a plurality of reaction channels disposed on a first side of the first porous substrate, the reaction channels defined by a barrier material disposed on a surface of the substrate in a user-defined pattern; and at least one reagent disposed within each reaction channel providing a colorimetric analysis of at least one analyte or property in a sample introduced to the device, wherein the first porous substrate is disposed within a housing, said housing comprising a first backing and a second backing, the first porous substrate being disposed between the first backing and the second backing, characterized in that the first backing comprises a first centrally located aperture defining a single sample port from which the sample travels radially outward to each of the reaction channels by capillary action and a plurality of second apertures positioned over corresponding reaction channels and, below the second backing, a second porous substrate and third backing, said second porous substrate having a plurality of reaction channels disposed on a first side thereof, and said third backing comprising a plurality of second apertures defining vents, wherein the reaction channels disposed on the first side of the first porous substrate provide one set of test results and the reaction channels disposed on the first side of the second porous substrate provide another set of results.
A charging member, comprising: a mandrel; and an electro-conductive elastic layer, wherein: the elastic layer has a universal hardness decreasing from a surface toward a depth direction thereof; characterized in that: the universal hardnesses of the elastic layer at a central portion and both end portions in a longitudinal direction of the charging member satisfy the following relationships: with respect to the surface of the elastic layer, the universal hardnesses at the both end portions are higher than that at the central portion; and with respect to a position having a depth of t μm from the surface of the elastic layer, the universal hardness at the central portion is higher than those at the both end portions. a mandrel; and an electro-conductive elastic layer, the elastic layer has a universal hardness decreasing from a surface toward a depth direction thereof; characterized in that: the universal hardnesses of the elastic layer at a central portion and both end portions in a longitudinal direction of the charging member satisfy the following relationships: with respect to the surface of the elastic layer, the universal hardnesses at the both end portions are higher than that at the central portion; and with respect to a position having a depth of t μm from the surface of the elastic layer, the universal hardness at the central portion is higher than those at the both end portions. the universal hardnesses of the elastic layer at a central portion and both end portions in a longitudinal direction of the charging member satisfy the following relationships: with respect to the surface of the elastic layer, the universal hardnesses at the both end portions are higher than that at the central portion; and with respect to a position having a depth of t μm from the surface of the elastic layer, the universal hardness at the central portion is higher than those at the both end portions. with respect to the surface of the elastic layer, the universal hardnesses at the both end portions are higher than that at the central portion; and with respect to a position having a depth of t μm from the surface of the elastic layer, the universal hardness at the central portion is higher than those at the both end portions.
Device for reducing sand bridges in a grit container of a sanding installation for a rail vehicle, which sanding installation is designed to spread grit accommodated in the grit container, via a downpipe, onto a rail carrying the rail vehicle, comprising a loosening device which is designed for loosening the grit, based on a loosening force oriented at an angle to the downpipe, and the downpipe, characterized by an intake head for the intake of the grit, said intake head being fastened above the downpipe as seen in a falling direction of the grit, the loosening device being provided for loosening the grit, based on a movement of the downpipe.
A memory device, comprising: a chalcogenide material memory storage element with a first surface and a second surface opposite the first surface, the second surface having a greater area than the first surface, wherein a logic state stored to the chalcogenide material memory storage element is based at least in part on the chalcogenide memory material storage element and a concentration of a chemical element relative to the first surface or the second surface, and wherein the concentration of the chemical element relative to the first surface or the second surface is based at least in part on a polarity of a voltage applied across the chalcogenide material memory storage element; a first electrode coupled with the first surface; and a second electrode coupled with the second surface and in electronic communication with the first electrode via the chalcogenide material memory storage element. a chalcogenide material memory storage element with a first surface and a second surface opposite the first surface, the second surface having a greater area than the first surface, wherein a logic state stored to the chalcogenide material memory storage element is based at least in part on the chalcogenide memory material storage element and a concentration of a chemical element relative to the first surface or the second surface, and wherein the concentration of the chemical element relative to the first surface or the second surface is based at least in part on a polarity of a voltage applied across the chalcogenide material memory storage element; a first electrode coupled with the first surface; and a second electrode coupled with the second surface and in electronic communication with the first electrode via the chalcogenide material memory storage element.
A blood purification device, comprising: a blood purifier, a washing liquid reservoir configured to have a washing liquid stored therein, a washing flow path configured to connect the blood purifier and the washing liquid reservoir to each other, a detector provided on the washing flow path configured to detect an air bubble, a discharge flow path configured to communicate with the blood purifier for discharging the washing liquid, a transfusion reservoir configured to store a transfusion therein, a pump provided on a flow path between the detector and the transfusion reservoir characterized in that the blood detection device comprises a control unit configured to activate the pump to supply the transfusion from the transfusion reservoir to the washing liquid reservoir via the detector when the detector is configured to detect an air bubble. a blood purifier, a washing liquid reservoir configured to have a washing liquid stored therein, a washing flow path configured to connect the blood purifier and the washing liquid reservoir to each other, a detector provided on the washing flow path configured to detect an air bubble, a discharge flow path configured to communicate with the blood purifier for discharging the washing liquid, a transfusion reservoir configured to store a transfusion therein, a pump provided on a flow path between the detector and the transfusion reservoir characterized in that the blood detection device comprises a control unit configured to activate the pump to supply the transfusion from the transfusion reservoir to the washing liquid reservoir via the detector when the detector is configured to detect an air bubble.
Method for predicting an increased risk of increased incompatibility propensity with respect to metallic implants in a test person, wherein, in a peripheral blood sample with genetic material from the test person: a) a SNV rs1143627 AGCCTCCTACTTCTGCTTTTGAAAGC[C/T]ATAAAAACAGCGAGGGAGAACTGG, SEQ ID NO: 1, in the gene encoding interleukin 1 beta, is analysed and it is determined that a C is present at the position of the SNV, and/or b) a VNTR polymorphism rs2234663 with the repeating unit in the gene encoding the IL1 receptor antagonist, IL1-RN, is analysed and it is determined that the repeating unit is present five times, and wherein the metal implants are joint endoprostheses. a) a SNV rs1143627 AGCCTCCTACTTCTGCTTTTGAAAGC[C/T]ATAAAAACAGCGAGGGAGAACTGG, SEQ ID NO: 1, in the gene encoding interleukin 1 beta, is analysed and it is determined that a C is present at the position of the SNV, and/or b) a VNTR polymorphism rs2234663 with the repeating unit in the gene encoding the IL1 receptor antagonist, IL1-RN, is analysed and it is determined that the repeating unit is present five times, and wherein the metal implants are joint endoprostheses. in the gene encoding the IL1 receptor antagonist, IL1-RN, is analysed and it is determined that the repeating unit is present five times, and wherein the metal implants are joint endoprostheses.
Nano-sized phthalocyanine pigment particles, comprising: a phthalocyanine chromogen structure as the main component, and a substituted soluble metal-phthalocyanine dye as a minor component that is associated non-covalently with the phthalocyanine chromogen structure, wherein the nano-sized phthalocyanine pigment particles have an average particle diameter of from 1 nm to 100 nm, and wherein the phthalocyanine is a metal-phthalocyanine, wherein the substituted soluble metal-phthalocyanine dye is wherein M is a metal or group of metals and atoms capable of bonding to the central cavity of the phthalocyanine molecule, and each R independently represents H or a sterically bulky substituent, provided that at least one R is other than hydrogen, wherein each R is attached to the periphery of the metal-phthalocyanine and is independently selected from the group consisting of substituted or unsubstituted alkyl, aryl, alkyaryl, or arylalkyl groups, having from 10 to 30 carbon atoms. a phthalocyanine chromogen structure as the main component, and a substituted soluble metal-phthalocyanine dye as a minor component that is associated non-covalently with the phthalocyanine chromogen structure, wherein the nano-sized phthalocyanine pigment particles have an average particle diameter of from 1 nm to 100 nm, and wherein the phthalocyanine is a metal-phthalocyanine, wherein the substituted soluble metal-phthalocyanine dye is wherein M is a metal or group of metals and atoms capable of bonding to the central cavity of the phthalocyanine molecule, and each R independently represents H or a sterically bulky substituent, provided that at least one R is other than hydrogen, wherein each R is attached to the periphery of the metal-phthalocyanine and is independently selected from the group consisting of substituted or unsubstituted alkyl, aryl, alkyaryl, or arylalkyl groups, having from 10 to 30 carbon atoms.
A method of demodulation reference signal, DMRS, transmission by a user equipment, UE, comprising: receiving, from a network entity, an uplink transmission configuration indication including a DMRS pattern for configuring DMRS transmission on an uplink communication channel, the DMRS pattern associated with one or more deployment characteristics; and transmitting a DMRS to the network entity on the uplink communication channel in accordance with the DMRS pattern; wherein the DMRS pattern corresponds to at least one of a first timeline-dependent DMRS pattern having one hybrid automatic repeat request, HARQ, interlace or a second timeline-dependent DMRS pattern having two or more HARQ interlaces. receiving, from a network entity, an uplink transmission configuration indication including a DMRS pattern for configuring DMRS transmission on an uplink communication channel, the DMRS pattern associated with one or more deployment characteristics; and transmitting a DMRS to the network entity on the uplink communication channel in accordance with the DMRS pattern; wherein the DMRS pattern corresponds to at least one of a first timeline-dependent DMRS pattern having one hybrid automatic repeat request, HARQ, interlace or a second timeline-dependent DMRS pattern having two or more HARQ interlaces.
Gastric retention active delivery system in the form of a coated capsule, comprising a sealed capsule encasing an effervescent formulation of one or more water soluble active components A, and a coating; wherein the coating comprises: - a total amount px of one or more pore forming components P, with px selected in the interval p1 < px < p2, wherein p1 = 1 mg/cm 2 and p2 = 11 mg/cm 2; - a total amount fx of one or more flexible polymer components F, with fx selected in the interval f1 < fx < f2, wherein f1 = 4 mg/cm 2 and f2 = 10 mg/cm 2, and wherein, further, 0.453 ∗ px + 3.49 mg/cm 2 < fx < 0.625 ∗ px + 4.75 mg/cm 2; - a total amount ex of one or more amphiphilic emulsifier components E, with ex selected in the interval e1 < ex < e2, wherein e1 = 0 and e2 = 0.1 ∗ fx; - a total amount tx of one or more anti-tacking components T, with tx selected in the interval t1 < tx < t2, wherein t1 = 0.5 ∗ fx and t2 = 2 ∗ fx; - a total amount nx of one or more non-water soluble excipients N, with nx selected in the interval n1 < nx < n2, wherein n1 = 0 and n2 = 0.1 ∗ fx; wherein flexible polymer components F are defined as neutral or virtually neutral (meth)acrylate copolymers composed of 20 wt% to 40 wt% of ethyl acrylate, 60 wt% to 80 wt% of methyl methacrylate and 0 to less than 5 wt% methacrylic acid or acrylic acid; wherein pore forming components P are defined as water soluble substances, including active components A, but excluding amphiphilic emulsifier components E; wherein, further, the effervescent formulation inside of the sealed capsule exhibits a gas generating capacity in the range of 60 Vol% to 140 Vol% of the total volume of the sealed capsule at 25 °C and 1013 mbar. - a total amount px of one or more pore forming components P, with px selected in the interval p1 < px < p2, wherein p1 = 1 mg/cm 2 and p2 = 11 mg/cm 2; with px selected in the interval p1 < px < p2, wherein p1 = 1 mg/cm 2 and p2 = 11 mg/cm 2; - a total amount fx of one or more flexible polymer components F, with fx selected in the interval f1 < fx < f2, wherein f1 = 4 mg/cm 2 and f2 = 10 mg/cm 2, and wherein, further, 0.453 ∗ px + 3.49 mg/cm 2 < fx < 0.625 ∗ px + 4.75 mg/cm 2; with fx selected in the interval f1 < fx < f2, wherein f1 = 4 mg/cm 2 and f2 = 10 mg/cm 2, and wherein, further, 0.453 ∗ px + 3.49 mg/cm 2 < fx < 0.625 ∗ px + 4.75 mg/cm 2; - a total amount ex of one or more amphiphilic emulsifier components E, with ex selected in the interval e1 < ex < e2, wherein e1 = 0 and e2 = 0.1 ∗ fx; with ex selected in the interval e1 < ex < e2, wherein e1 = 0 and e2 = 0.1 ∗ fx; - a total amount tx of one or more anti-tacking components T, with tx selected in the interval t1 < tx < t2, wherein t1 = 0.5 ∗ fx and t2 = 2 ∗ fx; with tx selected in the interval t1 < tx < t2, wherein t1 = 0.5 ∗ fx and t2 = 2 ∗ fx; - a total amount nx of one or more non-water soluble excipients N, with nx selected in the interval n1 < nx < n2, wherein n1 = 0 and n2 = 0.1 ∗ fx; with nx selected in the interval n1 < nx < n2, wherein n1 = 0 and n2 = 0.1 ∗ fx;
An exchange membrane unit comprising: a first separation membrane; a first space that is connected to a second space via the first separation membrane; a first path that supplies a first fluid to the first space and supplies chemical substances that have passed through the first separation membrane from the second space into the first space and diffused, to an ion detector using the first fluid discharged from the first space; and a first ionizing unit provided in the first space for generating radicals to activate a surface of the first separation membrane that faces the first space. a first separation membrane; a first space that is connected to a second space via the first separation membrane; a first path that supplies a first fluid to the first space and supplies chemical substances that have passed through the first separation membrane from the second space into the first space and diffused, to an ion detector using the first fluid discharged from the first space; and a first ionizing unit provided in the first space for generating radicals to activate a surface of the first separation membrane that faces the first space.
A curable resin composition, comprising: (a) a vinyl ester or unsaturated polyester in an amount of about 20 - 80 % by weight, based on the total weight of the composition; (b) a (meth)acrylate monomer having an olefin functionality of ≥ 3 in an amount of about 20 - 80 % by weight; based on the total weight of the composition, and (c) a synthesis catalyst for the production of the vinyl ester or unsaturated polyester which contains at least one reactive double bond. (a) a vinyl ester or unsaturated polyester in an amount of about 20 - 80 % by weight, based on the total weight of the composition; (b) a (meth)acrylate monomer having an olefin functionality of ≥ 3 in an amount of about 20 - 80 % by weight; based on the total weight of the composition, and (c) a synthesis catalyst for the production of the vinyl ester or unsaturated polyester which contains at least one reactive double bond.