mhurhangee/ep-ind-claims huggingface dataset:
A compound or pharmacologically acceptable salt thereof represented by the formula: wherein R 1 is a hydrogen atom; R 2 is an aromatic ring group selected from the group consisting of a phenyl group, a pyridinyl group, and a pyrimidinyl group, where the two atoms on the aromatic ring which are adjacent to the carbon atom attached to the pyrazolo[4,3-c]quinoline ring each independently has a substituent selected from Group A1, and the other atoms on the aromatic ring independently optionally have a substituent selected from Group B1; R 3 is a hydrogen atom, or a fluorine atom; R 4 is a hydrogen atom; R 5 is an oxepanyl group, a dioxepanyl group, a tetrahydropyranyl group, or a tetrahydrofuranyl group optionally having a methoxy group; R 6 is a hydrogen atom; Group A1 consists of a halogen atom, a C1-6 alkyl group optionally having 1 to 3 halogen atoms, and a C1-6 alkoxy group; and Group B1 consists of a halogen atom, a cyano group, a C1-6 alkyl group optionally having 1 to 3 halogen atoms, a C1-6 alkoxy-C1-6 alkyl group, a C1-6 alkoxy group optionally having 1 to 3 halogen atoms, and a tetrahydropyranyl group, with the proviso that when R 2 is a 3-pyridinyl group, the substituent at the 4-position is a halogen atom, or a C1-6 alkyl group optionally having 1 to 3 halogen atoms. R 1 is a hydrogen atom; R 2 is an aromatic ring group selected from the group consisting of a phenyl group, a pyridinyl group, and a pyrimidinyl group, where the two atoms on the aromatic ring which are adjacent to the carbon atom attached to the pyrazolo[4,3-c]quinoline ring each independently has a substituent selected from Group A1, and the other atoms on the aromatic ring independently optionally have a substituent selected from Group B1; R 3 is a hydrogen atom, or a fluorine atom; R 4 is a hydrogen atom; R 5 is an oxepanyl group, a dioxepanyl group, a tetrahydropyranyl group, or a tetrahydrofuranyl group optionally having a methoxy group; R 6 is a hydrogen atom; Group A1 consists of a halogen atom, a C1-6 alkyl group optionally having 1 to 3 halogen atoms, and a C1-6 alkoxy group; and Group B1 consists of a halogen atom, a cyano group, a C1-6 alkyl group optionally having 1 to 3 halogen atoms, a C1-6 alkoxy-C1-6 alkyl group, a C1-6 alkoxy group optionally having 1 to 3 halogen atoms, and a tetrahydropyranyl group, with the proviso that when R 2 is a 3-pyridinyl group, the substituent at the 4-position is a halogen atom, or a C1-6 alkyl group optionally having 1 to 3 halogen atoms.
A plastic packaging component comprising: a thermoplastic or thermoset resin forming a matrix; and an electromagnetic spectrally detectable additive of stainless steel particulate from 1-50 total weight percent of the component intermixed with said resin, said resin formed into a shape of the component, wherein the shape is one of an aerosol package lid, an aerosol spray button, an aerosol spray tube, an aerosol package clip-on extension holder for said tube, a trigger sprayer, an integrated lid sprayer, a grease cartridge, a grease cap, a packing strap, a pail lid, a jar cap, a brush or a plastic fibre towel sheet. a thermoplastic or thermoset resin forming a matrix; and an electromagnetic spectrally detectable additive of stainless steel particulate from 1-50 total weight percent of the component intermixed with said resin, said resin formed into a shape of the component, wherein the shape is one of an aerosol package lid, an aerosol spray button, an aerosol spray tube, an aerosol package clip-on extension holder for said tube, a trigger sprayer, an integrated lid sprayer, a grease cartridge, a grease cap, a packing strap, a pail lid, a jar cap, a brush or a plastic fibre towel sheet.
Hair-shaping appliance, comprising a device for treating a strand of hair, and at least one active-substance applicator (11, 11.1, 11.2, 11.3) that serves to condition the strand of hair held by the hair-shaping appliance, wherein the at least one active-substance applicator (11, 11.1, 11.2, 11.3) has an active-substance carrier (18, 18.1) which is arranged in an active-substance reservoir (15, 15.1) with the active substance contained therein in liquid form for the purposes of application; wherein the active-substance applicator (11, 11.1, 11.2, 11.3) comprises an application roller (12, 12.1, 12.2) which is rotatably mounted in the direction of movement of the strand of hair held by the hair-shaping appliance (1, 1.1) and guided past this; wherein the application roller (12, 12.1, 12.2) is in contact with its jacket surface over its circumference in a section and in the longitudinal direction substantially along the entire extent of its length at an active-substance reservoir mouth with the active-substance carrier (18, 18.1) located in the active-substance reservoir (15, 15.1) as well as, during the use of the hair-shaping device (1, 1.1), being in contact with hair held by the hair-shaping device (1, 1.1) and guided past the application roller (12, 12.1, 12.2) at an angular distance from the active-substance reservoir mouth; and wherein the application roller (12, 12.1, 12.2) is arranged such as to be rotated by the hair being guided past, for the purpose of an application of active substance to the hair in contact with the application roller (12, 12.1, 12.2).
A network processing method in network comprising a logical entity controlling at least one group of transmission points comprised in a plurality of transmission points forming a cell of a network according to a no-cell technology for uplink and downlink coordinated transmission with a terminal, characterized in that the method comprises: waiting, by a first network device, for a first time length after determining that the terminal is in a state out-of synchronization with the network which is called a network out-of-synchronization state in the following; instructing (201, 305), by a first network device if the first network device does not receive, in the first time length after the first network device determines that a terminal is in the network out-of-synchronization state, a measurement message reported by a second network device in a signal coverage area of the first network device based on an uplink tracking signal of the terminal, at least one second network device in the signal coverage area of the first network device to send paging signaling to the terminal wherein the first network device is the logical entity and each of the at least one second network device is one of the transmission points; and setting (202, 312), by the first network device, a network status of the terminal to a detached state if the first network device determines that in a second time length, no second network device in the signal coverage area of the first network device receives a paging response sent by the terminal, and that the terminal is still in the network out-of-synchronization state, wherein the paging response is a feedback message sent by the terminal after the terminal receives the paging signaling. waiting, by a first network device, for a first time length after determining that the terminal is in a state out-of synchronization with the network which is called a network out-of-synchronization state in the following; instructing (201, 305), by a first network device if the first network device does not receive, in the first time length after the first network device determines that a terminal is in the network out-of-synchronization state, a measurement message reported by a second network device in a signal coverage area of the first network device based on an uplink tracking signal of the terminal, at least one second network device in the signal coverage area of the first network device to send paging signaling to the terminal wherein the first network device is the logical entity and each of the at least one second network device is one of the transmission points; and setting (202, 312), by the first network device, a network status of the terminal to a detached state if the first network device determines that in a second time length, no second network device in the signal coverage area of the first network device receives a paging response sent by the terminal, and that the terminal is still in the network out-of-synchronization state, wherein the paging response is a feedback message sent by the terminal after the terminal receives the paging signaling.
A method for manufacturing an imprint mold, comprising: a winding step to wind a film mold onto a cylinder transfer roll, the film mold having a resin layer, the resin layer having a base pattern comprising a reverse pattern of a fine concave-convex pattern and the film mold being wound so as to form a clearance having no base pattern at a butting portion of both ends of the film mold; a resin filling step to fill a resin composition in the clearance; and a pattern forming step to form an additional pattern comprising a reverse pattern of a transfer pattern on the resin composition by pressing the transfer pattern provided on a pattern adding mold against the resin composition; wherein the resin composition is filled so as to form a protruding portion of the resin composition at a surface of the resin layer by allowing the resin composition to protrude from the clearance before the pattern adding mold is pressed against the resin composition or when the pattern adding mold is pressed against the resin composition, characterized in, that the protruding portion is removed from the surface of the resin layer by being adhered on the pattern adding mold when the pattern adding mold is removed from the resin composition. a winding step to wind a film mold onto a cylinder transfer roll, the film mold having a resin layer, the resin layer having a base pattern comprising a reverse pattern of a fine concave-convex pattern and the film mold being wound so as to form a clearance having no base pattern at a butting portion of both ends of the film mold; a resin filling step to fill a resin composition in the clearance; and a pattern forming step to form an additional pattern comprising a reverse pattern of a transfer pattern on the resin composition by pressing the transfer pattern provided on a pattern adding mold against the resin composition; wherein the resin composition is filled so as to form a protruding portion of the resin composition at a surface of the resin layer by allowing the resin composition to protrude from the clearance before the pattern adding mold is pressed against the resin composition or when the pattern adding mold is pressed against the resin composition, characterized in, that the protruding portion is removed from the surface of the resin layer by being adhered on the pattern adding mold when the pattern adding mold is removed from the resin composition.
Fusion protein, comprising a first domain (i), a second domain (ii) and a third domain (iii), wherein the second domain is disposed between the first and the third domain, wherein (i) comprises a partial sequence of a tetraspanin, which includes the transmembrane domain 1, the small extracellular loop, the transmembrane domain 2, the small intracellular loop and the transmembrane domain 3, or a sequence homologous thereto with a sequence identity of at least 95 % over the entire length, (ii) comprises a peptide with a predetermined amino-acid sequence, having a sequence identity of less than 70 % over the entire length in respect of the large extracellular loop of a tetraspanin and (iii) comprises a partial sequence of a tetraspanin, which includes the transmembrane domain 4 or a sequence homologous thereto with a sequence identity of at least 95 % over the entire length, and wherein flexible serine- and arginine-free linkers are disposed between the first and the second domain and/or between the second and the third domain, wherein the fusion protein is able to anchor in the membrane of a cell. (i) comprises a partial sequence of a tetraspanin, which includes the transmembrane domain 1, the small extracellular loop, the transmembrane domain 2, the small intracellular loop and the transmembrane domain 3, or a sequence homologous thereto with a sequence identity of at least 95 % over the entire length, (ii) comprises a peptide with a predetermined amino-acid sequence, having a sequence identity of less than 70 % over the entire length in respect of the large extracellular loop of a tetraspanin and (iii) comprises a partial sequence of a tetraspanin, which includes the transmembrane domain 4 or a sequence homologous thereto with a sequence identity of at least 95 % over the entire length,
A method to preserve starch present in pulp comprising: in a papermaking process having a head box or roundformer and process water containing pulp, treating said process water containing said pulp with chloramine comprising monochloramine such that said process water has a residual chloramine amount of from 0.3 ppm to 15 ppm at the head box or roundformer, and further treating said process water containing said pulp with at least one oxidant, wherein starch is present in said pulp in an amount of at least 0.001 wt % based on weight of dried pulp fiber, and wherein said chloramine is added based on measured calcium ion levels in said process water, said treating comprises continuously treating for at least 1 month and maintaining said residual chloramine amount, and production of amylase is controlled or prevented such that amylolytic bacteria are present in an amount of less than 1.0x10 15 cfu/g dry pulp in said process water. in a papermaking process having a head box or roundformer and process water containing pulp, treating said process water containing said pulp with chloramine comprising monochloramine such that said process water has a residual chloramine amount of from 0.3 ppm to 15 ppm at the head box or roundformer, and further treating said process water containing said pulp with at least one oxidant, wherein starch is present in said pulp in an amount of at least 0.001 wt % based on weight of dried pulp fiber, and wherein said chloramine is added based on measured calcium ion levels in said process water, said treating comprises continuously treating for at least 1 month and maintaining said residual chloramine amount, and production of amylase is controlled or prevented such that amylolytic bacteria are present in an amount of less than 1.0x10 15 cfu/g dry pulp in said process water.
An orally acceptable topical analgesic gel comprising: a mixture of analgesic oils comprising (a) clove oil and/or eugenol, (b) a cooling agent, and (c) camphor; and an orally acceptable gel base comprising: an anionic polymer and a basic amino acid; wherein the gel base provides controlled release of the mixture of analgesic oils following application to a tooth. a mixture of analgesic oils comprising (a) clove oil and/or eugenol, (b) a cooling agent, and (c) camphor; and an orally acceptable gel base comprising: an anionic polymer and a basic amino acid; an anionic polymer and a basic amino acid;
Floor panel assembly comprising sheet-shaped floor panels, preferably made of relatively resilient material, which floor panels are provided with a plurality of edges, wherein a first edge of a first panel and a second edge of a second panel are equipped with joining members (13, 14) which allow a joining of the first and second edges of the two panels by bringing these into engagement with each other in a relatively inclined position of the panels and then rotating said panels with respect to each other, so as to bring the upper sides of both panels substantially in alignment with each other and have them meet at a vertical plane VP, the first edge being provided with a tongue and the second edge with a groove adapted to receive the tongue therein so as to lock the panels at the adjacent edges at least in a direction perpendicular to the upper side and in a direction parallel to the upper side but perpendicular to the adjacent first and second edges in their joined position, wherein the tongue and groove are so adapted to each other that an upper surface of the tongue is urged against an upper wall of the groove, wherein the joining member of the second edge includes a lip below the groove having an upper protrusion and the joining member of the first edge includes a downwardly open recess behind the tongue, the upper protrusion being adapted to engage the recess to provide a horizontal lock, characterized in that the vertical size of the tongue is larger than the vertical size of the groove, in non-joined condition, such that in the joined position the tongue is compressed or bent in vertical direction in order to enable the tongue to be engaged in the groove.
A cartridge assembly for use with a surgical stapling instrument, the cartridge assembly comprising: a channel including a protrusion thereon; a cover configured for mechanical engagement with the channel, the cover including a blocking member and including a surface defining a plane; a staple cartridge configured for mechanical engagement with the cover; a knife configured for translation with respect to the cover and the staple cartridge; characterised in that: engagement between the channel and the cover causes the protrusion to move at least a portion of the blocking member from a first position where the blocking member is substantially parallel with the plane of the surface of the cover to a second position wherein at least a portion of the blocking member is spaced from the plane of the surface, wherein in the second position the cartridge assembly is configured to allow proximal translation of the knife past a predetermined position and the blocking member is configured to prevent distal translation of the knife after the knife has been translated proximally past the predetermined position. a channel including a protrusion thereon; a cover configured for mechanical engagement with the channel, the cover including a blocking member and including a surface defining a plane; a staple cartridge configured for mechanical engagement with the cover; a knife configured for translation with respect to the cover and the staple cartridge; engagement between the channel and the cover causes the protrusion to move at least a portion of the blocking member from a first position where the blocking member is substantially parallel with the plane of the surface of the cover to a second position wherein at least a portion of the blocking member is spaced from the plane of the surface, wherein in the second position the cartridge assembly is configured to allow proximal translation of the knife past a predetermined position and the blocking member is configured to prevent distal translation of the knife after the knife has been translated proximally past the predetermined position.
A liquid refill system, preferably for a fragrance composition comprising: a child device having a liquid reservoir having a volume and an air outlet valve said device having a first portion having a dispensing mechanism and a second portion having a child component of a refill mechanism comprising a child liquid inlet and a child one way liquid inlet refill valve associated therewith; and a parent device having a liquid reservoir containing a liquid and preferably an air inlet valve said device having an first portion having a parent component of a refill mechanism and a liquid outlet having a one way liquid valve associated therewith, said parent device having a pump and an actuator releasably attached to said parent device, wherein said pump has a pump volume, in liquid communication with the parent liquid reservoir via a one way liquid inlet valve and in liquid communication with said liquid outlet and optionally having a liquid return valve, wherein the ratio of the volume of the parent pump (Vpp) to the volume of the child liquid reservoir (Vcr) is 12:1 or less, preferably 1:1; and said actuator having an actuator stroke limitation means, whereby the maximum volume (Vpa) of liquid dispensed upon actuation of the actuator is predetermined and less than said pump volume (Vpp). a child device having a liquid reservoir having a volume and an air outlet valve said device having a first portion having a dispensing mechanism and a second portion having a child component of a refill mechanism comprising a child liquid inlet and a child one way liquid inlet refill valve associated therewith; and a parent device having a liquid reservoir containing a liquid and preferably an air inlet valve said device having an first portion having a parent component of a refill mechanism and a liquid outlet having a one way liquid valve associated therewith, said parent device having a pump and an actuator releasably attached to said parent device, wherein said pump has a pump volume, in liquid communication with the parent liquid reservoir via a one way liquid inlet valve and in liquid communication with said liquid outlet and optionally having a liquid return valve, wherein the ratio of the volume of the parent pump (Vpp) to the volume of the child liquid reservoir (Vcr) is 12:1 or less, preferably 1:1; and said actuator having an actuator stroke limitation means, whereby the maximum volume (Vpa) of liquid dispensed upon actuation of the actuator is predetermined and less than said pump volume (Vpp).
A compiling method for compiling a source code file of a code base, the method comprising: compiling the source code file of the code base using an optimizing compiler accordingly generating an intermediate representation; analyzing the intermediate representation to obtain and store characteristics of the code base, and using said characteristics of the code base in a subsequent compilation of the code base, wherein the characteristics of the code base are obtained by: obtaining history of a plurality of optimization passes; and analyzing the history of the optimizing passes to determine whether each optimization pass has an effect on at least one of a plurality of functions in the code base, characterized in that the optimizing compiler is updated based on said characteristics of the code base such that the optimizing compiler is then available as the optimizing compiler for the next iteration of the compilation process, wherein the method further comprises: obtaining reusable resources from the characteristics of the code base, optimizing compiled code using the reusable resources for use in the subsequent compilation, and rebuilding the optimized compiler according to the reusable resources for use in the subsequent compilation. compiling the source code file of the code base using an optimizing compiler accordingly generating an intermediate representation; analyzing the intermediate representation to obtain and store characteristics of the code base, and using said characteristics of the code base in a subsequent compilation of the code base, wherein the characteristics of the code base are obtained by: obtaining history of a plurality of optimization passes; and analyzing the history of the optimizing passes to determine whether each optimization pass has an effect on at least one of a plurality of functions in the code base, obtaining history of a plurality of optimization passes; and analyzing the history of the optimizing passes to determine whether each optimization pass has an effect on at least one of a plurality of functions in the code base, the optimizing compiler is updated based on said characteristics of the code base such that the optimizing compiler is then available as the optimizing compiler for the next iteration of the compilation process, wherein the method further comprises: obtaining reusable resources from the characteristics of the code base, optimizing compiled code using the reusable resources for use in the subsequent compilation, and rebuilding the optimized compiler according to the reusable resources for use in the subsequent compilation. obtaining reusable resources from the characteristics of the code base, optimizing compiled code using the reusable resources for use in the subsequent compilation, and rebuilding the optimized compiler according to the reusable resources for use in the subsequent compilation.