mhurhangee/ep-ind-claims huggingface dataset:
A method for identifying nucleic acid segments which interact with a target nucleic acid segment or segments, said method comprising the steps of: (a) obtaining a nucleic acid composition comprising the target nucleic acid segment or segments; (b) crosslinking the nucleic acid composition; (c) fragmenting the crosslinked nucleic acid composition using an endonuclease enzyme; (d) filling the ends of the fragmented crosslinked nucleic acid segments with one or more nucleotides comprising a covalently linked biotin moiety; (e) ligating the fragmented nucleic acid segments obtained from step (d) to produce ligated fragments; (f) performing single step fragmentation and oligonucleotide insertion on the ligated fragments using a recombinase enzyme; (g) enriching for fragments comprising the biotin moiety of step (d); (h) enriching fragments comprising the target nucleic acid segment or segments in the presence of sequences which prevent the binding of ligated fragments to other ligated fragments through complementarity of adapter sequences, such as blocker sequences; (i) sequencing the enriched fragments obtained in step (h) to identify the nucleic acid segments which interact with the target nucleic acid segment or segments. (a) obtaining a nucleic acid composition comprising the target nucleic acid segment or segments; (b) crosslinking the nucleic acid composition; (c) fragmenting the crosslinked nucleic acid composition using an endonuclease enzyme; (d) filling the ends of the fragmented crosslinked nucleic acid segments with one or more nucleotides comprising a covalently linked biotin moiety; (e) ligating the fragmented nucleic acid segments obtained from step (d) to produce ligated fragments; (f) performing single step fragmentation and oligonucleotide insertion on the ligated fragments using a recombinase enzyme; (g) enriching for fragments comprising the biotin moiety of step (d); (h) enriching fragments comprising the target nucleic acid segment or segments in the presence of sequences which prevent the binding of ligated fragments to other ligated fragments through complementarity of adapter sequences, such as blocker sequences; (i) sequencing the enriched fragments obtained in step (h) to identify the nucleic acid segments which interact with the target nucleic acid segment or segments.
Device for analysing the composition of the contents of a container comprising: - means for emitting/receiving an electromagnetic field at at least several frequencies included within a determined frequency range, - means for supporting a container of which the contents are to be analysed, suitable for ensuring a precise relative positioning between the emitting/receiving means and the container, - means able to measure the complex impedance of the emitting/receiving means influenced by the charge formed by the container and its contents, representative of the complex dielectric characteristics of the container and of its contents, characterised in that it further comprises means for spectrally analysing the contents of the container in order to measure the absorption of waves by the container and its contents, and means able to provide information relative to the nature of the contents of said container according to the complex impedance measured and the absorption measurement, the means of spectral analysis are able to emit waves of which the wavelengths are between 1100 nm and 31 μm. - means for emitting/receiving an electromagnetic field at at least several frequencies included within a determined frequency range, - means for supporting a container of which the contents are to be analysed, suitable for ensuring a precise relative positioning between the emitting/receiving means and the container, - means able to measure the complex impedance of the emitting/receiving means influenced by the charge formed by the container and its contents, representative of the complex dielectric characteristics of the container and of its contents,
A method, comprising: reading cells in a memory device; and scanning for errors in information stored in the memory device when a number of read operations in the memory device exceeds a selected value, characterised in that the selected value is a predetermined value, the selected value is determined based on a relationship between a number of read operations (X, N) during a test and error rates (R1, R2, R3) corresponding to the number of read operations during the test, and the selected value corresponds to the number of read operations during the test at which the error rates increase from a linear fashion to an exponential fashion. reading cells in a memory device; and scanning for errors in information stored in the memory device when a number of read operations in the memory device exceeds a selected value, characterised in that the selected value is a predetermined value, the selected value is determined based on a relationship between a number of read operations (X, N) during a test and error rates (R1, R2, R3) corresponding to the number of read operations during the test, and the selected value corresponds to the number of read operations during the test at which the error rates increase from a linear fashion to an exponential fashion.
A method operating at a user equipment device configured to engage in an adaptive bitrate streaming session via Dynamic Adaptive Streaming over HTTP (DASH), the method comprising: receiving one or more media presentation description documents (MPDs) with respect to a content program, each MPD having a segment template element that identifies one or more directory limit indicia, wherein the content program is segmented into a plurality of segments that are stored across multiple directories of a media server file system, the one or more directory limit indicia operating to indicate a maximum number of media segments stored in each directory; parsing the segment template element of the one or more MPDs; constructing resource locators based on the one or more directory limit indicia provided in the MPDs, the resource locators configured for accessing media segments of the content program from the multiple directories of the media server file system; and generating HTTP requests using the constructed resource locators to obtain media segments of the content program from the multiple directories of the media server file system. receiving one or more media presentation description documents (MPDs) with respect to a content program, each MPD having a segment template element that identifies one or more directory limit indicia, wherein the content program is segmented into a plurality of segments that are stored across multiple directories of a media server file system, the one or more directory limit indicia operating to indicate a maximum number of media segments stored in each directory; parsing the segment template element of the one or more MPDs; constructing resource locators based on the one or more directory limit indicia provided in the MPDs, the resource locators configured for accessing media segments of the content program from the multiple directories of the media server file system; and generating HTTP requests using the constructed resource locators to obtain media segments of the content program from the multiple directories of the media server file system.
A vessel assembly configured to discharge a high pressure mixture of water and abrasives (54, 54') for admixture with a flow of high pressure water for generating an abrasive slurry, the vessel assembly comprising: a storage chamber to temporarily store abrasives (54, 54); a discharge chamber having an outlet to selectively discharge the high pressure mixture of water and abrasives (54, 54') into the flow of high pressure water to mix therewith and generate the abrasive slurry; the vessel assembly is characterized by a shuttle chamber positioned downstream of the storage chamber and upstream of the discharge chamber to intermittently receive the abrasives (54, 54') from the storage chamber and to intermittently supply the abrasives (54, 54') mixed with high pressure water to the discharge chamber, the shuttle chamber including an inlet port coupleable to a source of high pressure water to intermittently receive the high pressure water and intermittently pressurize the shuttle chamber to create the high pressure mixture of water and abrasives (54, 54') to be transferred to the discharge chamber. a storage chamber to temporarily store abrasives (54, 54); a discharge chamber having an outlet to selectively discharge the high pressure mixture of water and abrasives (54, 54') into the flow of high pressure water to mix therewith and generate the abrasive slurry; the vessel assembly is characterized by a shuttle chamber positioned downstream of the storage chamber and upstream of the discharge chamber to intermittently receive the abrasives (54, 54') from the storage chamber and to intermittently supply the abrasives (54, 54') mixed with high pressure water to the discharge chamber, the shuttle chamber including an inlet port coupleable to a source of high pressure water to intermittently receive the high pressure water and intermittently pressurize the shuttle chamber to create the high pressure mixture of water and abrasives (54, 54') to be transferred to the discharge chamber.
A trailer brake control method, comprising: determining (202, 354), based on information from a vehicle speed sensor (200, 350), a current vehicle speed of a vehicle; at all vehicle speeds of the vehicle, determining, using a processing unit, a minimum trailer brake control value (MTBCV) based on the equation MTBCV = R1 - Cth root(the current vehicle speed)/R2, wherein the minimum trailer brake control value corresponds to a minimum braking force at the current vehicle speed, R1 is a real number less than 1.0, Cis an integer greater than 2, and R2 is a real number greater than 1.0; determining, using the processing unit, a trailer brake command signal based on the minimum trailer brake control value; and operating brakes of a trailer connected to the vehicle at or above the minimum braking force by transmitting the trailer brake command signal from the vehicle to a trailer. determining (202, 354), based on information from a vehicle speed sensor (200, 350), a current vehicle speed of a vehicle; at all vehicle speeds of the vehicle, determining, using a processing unit, a minimum trailer brake control value (MTBCV) based on the equation MTBCV = R1 - Cth root(the current vehicle speed)/R2, wherein the minimum trailer brake control value corresponds to a minimum braking force at the current vehicle speed, R1 is a real number less than 1.0, Cis an integer greater than 2, and R2 is a real number greater than 1.0; determining, using the processing unit, a trailer brake command signal based on the minimum trailer brake control value; and operating brakes of a trailer connected to the vehicle at or above the minimum braking force by transmitting the trailer brake command signal from the vehicle to a trailer.
A furnace for preparing fused (homogenised) samples for sample analysis, the furnace comprising: a housing; a heater arranged for heating an interior portion of the housing to a temperature sufficient for causing melting of each sample; a carousel positioned in the housing, the carousel having a plurality of receiving stations for receiving crucibles containing respective samples, the carousel being arranged for rotating the crucibles about an axis when the crucibles are positioned in respective receiving stations; and a mechanism for moving the crucibles relative to the respective receiving stations and relative to the housing to load and unload the carousel; characterised in that the mechanism for moving the crucibles is arranged to move the crucibles in a direction that has a component perpendicular to the axis about which the carousel is arranged to move the crucibles; and in that the housing has an access port in a side wall portion through which in use the crucibles are moved by the mechanism for moving the crucibles. a housing; a heater arranged for heating an interior portion of the housing to a temperature sufficient for causing melting of each sample; a carousel positioned in the housing, the carousel having a plurality of receiving stations for receiving crucibles containing respective samples, the carousel being arranged for rotating the crucibles about an axis when the crucibles are positioned in respective receiving stations; and a mechanism for moving the crucibles relative to the respective receiving stations and relative to the housing to load and unload the carousel; characterised in that the mechanism for moving the crucibles is arranged to move the crucibles in a direction that has a component perpendicular to the axis about which the carousel is arranged to move the crucibles; and in that the housing has an access port in a side wall portion through which in use the crucibles are moved by the mechanism for moving the crucibles.
A compound of general formula: where R a and R b independently represent a 5 or 6-membered aryl radical optionally substituted by a halogen or a branched or unbranched, saturated alkyl radicalC 1-6; a 5 or 6-membered heteroaryl radical having at least one heteroatom selected from N, O or S as ring member, optionally substituted by a halogen or a branched or unbranched, saturated alkyl radical C 1-6; or the following moiety: with the proviso that one of R a and R b represents this moiety and the other one represents 5 or 6-membered aryl radical optionally substituted by a halogen or a branched or unbranched, saturated alkyl radical C 1-6; or a 5 or 6-membered heteroaryl radical having at least one heteroatom selected from N, O or S as ring member, optionally substituted by a halogen or a branched or unbranched, saturated alkyl radical C 1-6 A is a C or O; B is a C or N; R 1 and R 2 independently represent a H, or R 1 and R 2 together with the bridging N form an 5 to 7-membered heterocyclic ring which can have at least one additional heteroatom selected from N, O or S and that can be optionally substituted by a branched or unbranched, saturated alkyl radical C 1-6 or by an aryl radical optionally substituted by an alkyl C 1-6, a halogen or an OH group; n is 0, 1 or 2; m is 0, 1, 2, 3 or 4; with the proviso that when A is O m is different from 0; and with the proviso that when B represents a C and R b represents a phenyl substituted by a halogen, R a cannot represent the moiety: with R 1 and R 2 together with the bridging N forming a piperazine, or a pharmaceutically acceptable salt, enantiomer and geometric/diasterisomeric isomer or solvate thereof. R a and R b independently represent a 5 or 6-membered aryl radical optionally substituted by a halogen or a branched or unbranched, saturated alkyl radicalC 1-6; a 5 or 6-membered heteroaryl radical having at least one heteroatom selected from N, O or S as ring member, optionally substituted by a halogen or a branched or unbranched, saturated alkyl radical C 1-6; or the following moiety: with the proviso that one of R a and R b represents this moiety and the other one represents 5 or 6-membered aryl radical optionally substituted by a halogen or a branched or unbranched, saturated alkyl radical C 1-6; or a 5 or 6-membered heteroaryl radical having at least one heteroatom selected from N, O or S as ring member, optionally substituted by a halogen or a branched or unbranched, saturated alkyl radical C 1-6 A is a C or O; B is a C or N; R 1 and R 2 independently represent a H, or R 1 and R 2 together with the bridging N form an 5 to 7-membered heterocyclic ring which can have at least one additional heteroatom selected from N, O or S and that can be optionally substituted by a branched or unbranched, saturated alkyl radical C 1-6 or by an aryl radical optionally substituted by an alkyl C 1-6, a halogen or an OH group; n is 0, 1 or 2; m is 0, 1, 2, 3 or 4;
A device for measuring a varying physical quantity such as e.g. pressure, comprising - a sensor which outputs an analog measurement signal, and - a signal processing unit having an input receiving the measurement signal of the sensor and an output for outputting the processed measuring signal, - wherein the signal processing unit is provided with - an analog rectangular frequency mixer arranged at its input, for frequency-shifting the measurement signal of the sensor by a shift frequency f D towards higher frequencies, - an amplifier for amplifying the frequency-shifted measuring signal, wherein the amplifier generates an amplifier offset, and - an analog-to-digital converter for converting the amplified analog signal of the amplifier into a digital signal, characterized by - a digital sine frequency mixer arranged at the output of the signal processing unit for shifting of the output signal of the analog-to-digital converter by the shift frequency f D towards lower frequencies, and - a first filter connected downstream of the digital sine frequency mixer and arranged at the output of the signal processing unit, for suppressing, at odd harmonics of the frequency shift f D, signal components caused by the analog rectangular frequency mixer and shifted downward in their frequency by the digital sine frequency mixer. - a sensor which outputs an analog measurement signal, and - a signal processing unit having an input receiving the measurement signal of the sensor and an output for outputting the processed measuring signal, - wherein the signal processing unit is provided with - an analog rectangular frequency mixer arranged at its input, for frequency-shifting the measurement signal of the sensor by a shift frequency f D towards higher frequencies, - an amplifier for amplifying the frequency-shifted measuring signal, wherein the amplifier generates an amplifier offset, and - an analog-to-digital converter for converting the amplified analog signal of the amplifier into a digital signal, characterized by - an analog rectangular frequency mixer arranged at its input, for frequency-shifting the measurement signal of the sensor by a shift frequency f D towards higher frequencies, - an amplifier for amplifying the frequency-shifted measuring signal, wherein the amplifier generates an amplifier offset, and - an analog-to-digital converter for converting the amplified analog signal of the amplifier into a digital signal, - a digital sine frequency mixer arranged at the output of the signal processing unit for shifting of the output signal of the analog-to-digital converter by the shift frequency f D towards lower frequencies, and - a first filter connected downstream of the digital sine frequency mixer and arranged at the output of the signal processing unit, for suppressing, at odd harmonics of the frequency shift f D, signal components caused by the analog rectangular frequency mixer and shifted downward in their frequency by the digital sine frequency mixer.
A cable shovel bucket comprising a shell and a door collectively defining a cavity for gathering material during operation of the cable shovel, the shell including a front wall, an opposite back wall and sidewalls extending between the front wall and the back wall, characterized in that the back wall has an exterior surface to which the cable shovel is connected when the bucket is in a dumping position, the door being pivotally secured to the shell, for gravity activated movement between an open position and a closed position about a pivot axis that extends forward of the exterior surface of the back wall of the shell, along a distance between back wall and a center of gravity of the loaded door.
An IV catheter comprising: a catheter having a wall defining a lumen, a proximal end, and a distal end; an adapter having a proximal end, a distal end and an internal cavity, said adapter being in fluid communication with the catheter lumen; a septum positioned within the adapter cavity at the adapter proximal end; an extension tube extending laterally from the adapter and in fluid communication with adapter cavity; a tip shield having a distal end, a proximal end and an internal cavity, said shield positioned adjacent adapter proximal end and coaxially aligned with adapter; a hub having a proximal portion, a distal portion and an internal cavity, said hub positioned adjacent the tip shield proximal end and coaxially aligned with the tip shield; a cannula having a wall defining a lumen, a beveled distal end, an aperture in the wall of said cannula near the cannula distal end and a proximal end in the shape of a hook, said cannula passing through and coaxially aligned with the catheter, adapter, tip shield and hub; characterized by a glue wall which firmly grips the hook to maintain the needle cannula firmly in place with respect to the needle hub while ensuring that the proximal end of the needle cannula is sealed. a catheter having a wall defining a lumen, a proximal end, and a distal end; an adapter having a proximal end, a distal end and an internal cavity, said adapter being in fluid communication with the catheter lumen; a septum positioned within the adapter cavity at the adapter proximal end; an extension tube extending laterally from the adapter and in fluid communication with adapter cavity; a tip shield having a distal end, a proximal end and an internal cavity, said shield positioned adjacent adapter proximal end and coaxially aligned with adapter; a hub having a proximal portion, a distal portion and an internal cavity, said hub positioned adjacent the tip shield proximal end and coaxially aligned with the tip shield; a cannula having a wall defining a lumen, a beveled distal end, an aperture in the wall of said cannula near the cannula distal end and a proximal end in the shape of a hook, said cannula passing through and coaxially aligned with the catheter, adapter, tip shield and hub; characterized by a glue wall which firmly grips the hook to maintain the needle cannula firmly in place with respect to the needle hub while ensuring that the proximal end of the needle cannula is sealed.
A method in a first wireless device of relaying data from a second wireless device to a wireless communication network, the method comprising: obtaining data transmission pattern information associated with data to be relayed from the second wireless device to the wireless communication network, wherein the data comprises a plurality of data bursts, and the data transmission pattern information includes a periodicity of the data bursts, and an amount of data associated with each of the data bursts; in advance of receiving the data from the second wireless device, requesting,from the wireless communication network, resources for multiple data transmissions according to the data transmission pattern information, and receiving an indication of resources from the wireless communication network, wherein the indicated resources comprise semi-persistently scheduled resources; receiving the data from the second wireless device; and transmitting the data to the wireless communication network using the indicated resources. obtaining data transmission pattern information associated with data to be relayed from the second wireless device to the wireless communication network, wherein the data comprises a plurality of data bursts, and the data transmission pattern information includes a periodicity of the data bursts, and an amount of data associated with each of the data bursts; in advance of receiving the data from the second wireless device, requesting,from the wireless communication network, resources for multiple data transmissions according to the data transmission pattern information, and receiving an indication of resources from the wireless communication network, wherein the indicated resources comprise semi-persistently scheduled resources; receiving the data from the second wireless device; and transmitting the data to the wireless communication network using the indicated resources.