Compounds of the formula I in which R 1 denotes phenyl, benzyl, naphthyl or biphenyl, each of which is unsubstituted or mono-, di-, tri-, tetra- or pentasubstituted by Hal, CN, NHCOA, NHSO 2 A, SO 2 A and/or CONH 2; A or (CH 2) n Het, R 2 denotes [C(R 4) 2] n Ar 2, (CH 2) n Cyc, CH[B 2]CH 2 Het, CH(C≡CH)phenyl, A or (CH 2) n Het, R 3 denotes OH, N 3, NH 2 or F, R 4 denotes H or alkyl having 1, 2, 3 or 4 C atoms, R 2 and R 4 together also denote alkylene having 2, 3, 4 or 5 C atoms, where one CH 2 group may also be replaced by NH, NA, N-COA, N-(CH 2) n Ar 3, N-(CH 2) n Het 2, CH-A, CH-O-(CH 2) n Ar 3, N-SO 2 A or O and/or may be substituted by A, Het denotes pyridazinyl, pyrazolyl, benzimidazolyl, pyridyl, dibenzofuranyl, carbazolyl, indolyl, dihydroindolyl, benzofuranyl, dihydrobenzofuranyl, 2,3-dihydrobenzo-1,4-dioxinyl, chromanyl, piperazinyl, morpholinyl, tetrahydropyranyl, quinolinyl, isoquinolinyl, isoindolyl, dihydroquinolinyl, dihydroisoquinolinyl, tetrahydroquinolinyl, tetrahydroiso-quinolinyl, quinazolinyl, quinoxalinyl, phthalazinyl, purinyl, naphthyridinyl, pyrimidinyl, indazolyl, furyl, thienyl, imidazolyl, pyrrolyl, oxazolyl, oxadiazolyl, isoxazolyl, thiazolyl, triazolyl, tetrazolyl, thiadiazole, benzothiazolyl, imidazo[1,2-a]-pyridinyl, 1,3-benzodioxolyl, benzoxazolyl, piperidin-1-yl, pyrrolidin-1-yl, 1,2-oxazinan-2-yl, 1,2,5-oxadiazinan-2-yl, 1,3-oxazinan-3-yl or hexahydropyrimidinyl, each of which is unsubstituted or mono-, di- or trisubstituted by A, OA, COOA, COA, CHO, (CH 2) n CONH 2, (CH 2) n CONHA, (CH 2) n CONA 2, SO 2 A, NHSO 2 A, =O and/or Het 1, Het 1 denotes pyridazinyl, pyrazolyl, pyridyl, piperazinyl, morpholinyl, pyrimidinyl, furyl, thienyl, imidazolyl, pyrrolyl, oxazolyl, isoxazolyl, thiazolyl, triazolyl, tetrazolyl, thiadiazole, piperidin-1-yl, pyrrolidin-1-yl, tetrahydropyranyl, 1,2-oxazinan-2-yl, 1,2,5-oxadiazinan-2-yl, 1,3-oxazinan-3-yl or hexahydropyrimidinyl, each of which is unsubstituted or mono-, di- or trisubstituted by A and/or OA, Het 2 denotes pyridyl, pyrimidinyl, furyl, thienyl, imidazolyl, pyrrolyl, oxazolyl, oxadiazolyl, isoxazolyl, thiazolyl, triazolyl, tetrazolyl or thiadiazole, A denotes unbranched or branched alkyl having 1-10 C atoms, in which 1-7 H atoms may be replaced by F, Cl, Br, OH, CHO, COA, COOA, CN, CONA 2, CONHA and/or CONH 2, and/or in which one or two non-adjacent CH and/or CH 2 groups may be replaced by O, N and/or NR 4, or Cyc, Ar 2 denotes phenyl which is unsubstituted or mono-, di-, tri-, tetra- or pentasubstituted by A, Hal, CN, OH and/or OA, Ar 3 denotes phenyl which is unsubstituted or mono-, di- or trisubstituted by Hal, OH, OA and/or A, Cyc denotes cyclic alkyl having 3-7 C atoms, Hal denotes F, Cl, Br or I, n denotes 0, 1, 2, 3 or 4, and pharmaceutically usable salts, tautomers and stereoisomers thereof, including mixtures thereof in all ratios. R 1 denotes phenyl, benzyl, naphthyl or biphenyl, each of which is unsubstituted or mono-, di-, tri-, tetra- or pentasubstituted by Hal, CN, NHCOA, NHSO 2 A, SO 2 A and/or CONH 2; A or (CH 2) n Het, R 2 denotes [C(R 4) 2] n Ar 2, (CH 2) n Cyc, CH[B 2]CH 2 Het, CH(C≡CH)phenyl, A or (CH 2) n Het, R 3 denotes OH, N 3, NH 2 or F, R 4 denotes H or alkyl having 1, 2, 3 or 4 C atoms, R 2 and R 4 together also denote alkylene having 2, 3, 4 or 5 C atoms, where one CH 2 group may also be replaced by NH, NA, N-COA, N-(CH 2) n Ar 3, N-(CH 2) n Het 2, CH-A, CH-O-(CH 2) n Ar 3, N-SO 2 A or O and/or may be substituted by A, Het denotes pyridazinyl, pyrazolyl, benzimidazolyl, pyridyl, dibenzofuranyl, carbazolyl, indolyl, dihydroindolyl, benzofuranyl, dihydrobenzofuranyl, 2,3-dihydrobenzo-1,4-dioxinyl, chromanyl, piperazinyl, morpholinyl, tetrahydropyranyl, quinolinyl, isoquinolinyl, isoindolyl, dihydroquinolinyl, dihydroisoquinolinyl, tetrahydroquinolinyl, tetrahydroiso-quinolinyl, quinazolinyl, quinoxalinyl, phthalazinyl, purinyl, naphthyridinyl, pyrimidinyl, indazolyl, furyl, thienyl, imidazolyl, pyrrolyl, oxazolyl, oxadiazolyl, isoxazolyl, thiazolyl, triazolyl, tetrazolyl, thiadiazole, benzothiazolyl, imidazo[1,2-a]-pyridinyl, 1,3-benzodioxolyl, benzoxazolyl, piperidin-1-yl, pyrrolidin-1-yl, 1,2-oxazinan-2-yl, 1,2,5-oxadiazinan-2-yl, 1,3-oxazinan-3-yl or hexahydropyrimidinyl, each of which is unsubstituted or mono-, di- or trisubstituted by A, OA, COOA, COA, CHO, (CH 2) n CONH 2, (CH 2) n CONHA, (CH 2) n CONA 2, SO 2 A, NHSO 2 A, =O and/or Het 1, Het 1 denotes pyridazinyl, pyrazolyl, pyridyl, piperazinyl, morpholinyl, pyrimidinyl, furyl, thienyl, imidazolyl, pyrrolyl, oxazolyl, isoxazolyl, thiazolyl, triazolyl, tetrazolyl, thiadiazole, piperidin-1-yl, pyrrolidin-1-yl, tetrahydropyranyl, 1,2-oxazinan-2-yl, 1,2,5-oxadiazinan-2-yl, 1,3-oxazinan-3-yl or hexahydropyrimidinyl, each of which is unsubstituted or mono-, di- or trisubstituted by A and/or OA, Het 2 denotes pyridyl, pyrimidinyl, furyl, thienyl, imidazolyl, pyrrolyl, oxazolyl, oxadiazolyl, isoxazolyl, thiazolyl, triazolyl, tetrazolyl or thiadiazole, A denotes unbranched or branched alkyl having 1-10 C atoms, in which 1-7 H atoms may be replaced by F, Cl, Br, OH, CHO, COA, COOA, CN, CONA 2, CONHA and/or CONH 2, and/or in which one or two non-adjacent CH and/or CH 2 groups may be replaced by O, N and/or NR 4, or Cyc, Ar 2 denotes phenyl which is unsubstituted or mono-, di-, tri-, tetra- or pentasubstituted by A, Hal, CN, OH and/or OA, Ar 3 denotes phenyl which is unsubstituted or mono-, di- or trisubstituted by Hal, OH, OA and/or A, Cyc denotes cyclic alkyl having 3-7 C atoms, Hal denotes F, Cl, Br or I, n denotes 0, 1, 2, 3 or 4,