An industrial centrifuge for extracting one or more compounds from biomass, the industrial centrifuge comprising: a centrifuge basket disposed within a cylindrical vessel, the centrifuge basket comprising: a sidewall comprising an upper perforated portion and a lower solid portion, where the sidewall is cylindrical; a basket baseplate coupled to an inner surface of the sidewall between the upper perforated portion and the lower solid portion; and a spindle coupled to the basket baseplate and operatively coupled to a drive mechanism (60, 80) operable to rotate the spindle about an axis; a spindle bearing assembly coupled to the cylindrical vessel and disposed between a bottom of the cylindrical vessel and the basket baseplate; and a contact seal disposed between the spindle bearing assembly and the basket baseplate; wherein: the spindle passes vertically through the spindle bearing assembly and extends vertically downward to the drive mechanism (60, 80) disposed vertically below the bottom of the cylindrical vessel; the lower solid portion of the sidewall, a portion of the spindle, and the basket baseplate define a skirted volume; at least a portion of the spindle bearing assembly is disposed within the skirted volume; and during operation of the industrial centrifuge, an air bubble trapped within the skirted volume provides an air seal between an extraction fluid in the cylindrical vessel and the contact seal. a centrifuge basket disposed within a cylindrical vessel, the centrifuge basket comprising: a sidewall comprising an upper perforated portion and a lower solid portion, where the sidewall is cylindrical; a basket baseplate coupled to an inner surface of the sidewall between the upper perforated portion and the lower solid portion; and a sidewall comprising an upper perforated portion and a lower solid portion, where the sidewall is cylindrical; a basket baseplate coupled to an inner surface of the sidewall between the upper perforated portion and the lower solid portion; and a spindle coupled to the basket baseplate and operatively coupled to a drive mechanism (60, 80) operable to rotate the spindle about an axis; a spindle bearing assembly coupled to the cylindrical vessel and disposed between a bottom of the cylindrical vessel and the basket baseplate; and a contact seal disposed between the spindle bearing assembly and the basket baseplate; wherein: the spindle passes vertically through the spindle bearing assembly and extends vertically downward to the drive mechanism (60, 80) disposed vertically below the bottom of the cylindrical vessel; the lower solid portion of the sidewall, a portion of the spindle, and the basket baseplate define a skirted volume; at least a portion of the spindle bearing assembly is disposed within the skirted volume; and during operation of the industrial centrifuge, an air bubble trapped within the skirted volume provides an air seal between an extraction fluid in the cylindrical vessel and the contact seal. the spindle passes vertically through the spindle bearing assembly and extends vertically downward to the drive mechanism (60, 80) disposed vertically below the bottom of the cylindrical vessel; the lower solid portion of the sidewall, a portion of the spindle, and the basket baseplate define a skirted volume; at least a portion of the spindle bearing assembly is disposed within the skirted volume; and during operation of the industrial centrifuge, an air bubble trapped within the skirted volume provides an air seal between an extraction fluid in the cylindrical vessel and the contact seal.