mhurhangee/ep-ind-claims huggingface dataset:
An oxidative dyeing composition characterized in that it comprises at least one dyestuff and one or more compound selected from avenanthramide A, avenanthramide B, avenanthramide, dihydroavenanthramide A, dihydroavenanthramide B, dihydroavenanthramide C, and hydroxyphenyl propamidobenzoic acid, and/or their salts and their mixtures, at least one alkalizing agent selected from ammonia or ammonium hydroxide and a compound according to the general formula R 1 R 2 R 3 N wherein R 1, R 2 and R 3 are same or different H, C1 - C6 alkyl, C1 - C6 monohydroxyalkyl or C2 - C6 polyhydroxyalkyl with the condition that at least one of R 1, R 2 and R 3 is a mono or polyhydroxyalkyl, and it has a pH in the range of 6.8 to 12.
A method for knotting glass fiber bundles, comprising the following steps of: equally dividing a glass fiber bundle A and a glass fiber bundle B that are to be connected by knotting into n strands, respectively, and marking the strands as A1-An and B1-Bn, respectively, wherein n is a natural number greater than or equal to 2; and successively knotting and splicing the glass fiber strands A1-An and the glass fiber strands B1-Bn in one-to-one correspondence to form n spliced knots; characterized in that: the n spliced knots are staggered in pairs in a lengthwise direction of the glass fiber bundles; a distance L between two adjacent spliced knots among the n spliced knots in the lengthwise direction of the glass fiber bundles is greater than or equal to a length C of the spliced knots, wherein L is set to 3 cm, 5 cm or 10 cm; wherein: the sectional area of the whole glass fiber bundle is S, the sectional area of each equally divided fiber bundle is S/n, and the sectional area of the knots is (4S/n)+(n-1)*S/n=3S/n+S. equally dividing a glass fiber bundle A and a glass fiber bundle B that are to be connected by knotting into n strands, respectively, and marking the strands as A1-An and B1-Bn, respectively, wherein n is a natural number greater than or equal to 2; and successively knotting and splicing the glass fiber strands A1-An and the glass fiber strands B1-Bn in one-to-one correspondence to form n spliced knots; characterized in that: the n spliced knots are staggered in pairs in a lengthwise direction of the glass fiber bundles; a distance L between two adjacent spliced knots among the n spliced knots in the lengthwise direction of the glass fiber bundles is greater than or equal to a length C of the spliced knots, wherein L is set to 3 cm, 5 cm or 10 cm; the n spliced knots are staggered in pairs in a lengthwise direction of the glass fiber bundles; a distance L between two adjacent spliced knots among the n spliced knots in the lengthwise direction of the glass fiber bundles is greater than or equal to a length C of the spliced knots, wherein L is set to 3 cm, 5 cm or 10 cm; wherein: the sectional area of the whole glass fiber bundle is S, the sectional area of each equally divided fiber bundle is S/n, and the sectional area of the knots is (4S/n)+(n-1)*S/n=3S/n+S.
A method for determining a direction attached to a solid, the solid having four visible points (P 1 -P 4), arranged such that two first (P 1, P 2) of said points and two second (P 3, P 4) of said points define respectively a first vector (P 1 P 2) and a second vector (P 3 P 4) parallel to each other and oriented in the direction to be determined, the method comprising the following step: a) using a computer, identifying in one image of said solid the positions (I i) of said four points; the method being characterized in that it further comprises the following steps: b) using the intrinsic, parameters of the camera and from said positions, using a computer, determining the coordinates of normal vectors (N 1, N 2) which are normal to two planes: - the first plane passing through the optical center and said two first points (P 1, P 2), and - the second plane passing through the optical center and the said two second points (P 3, P 4); and c) using a computer, determining the coordinates of a vector collinear to said parallel vectors by calculating the vector product of said normal vectors (N 1, N 2). a) using a computer, identifying in one image of said solid the positions (I i) of said four points; b) using the intrinsic, parameters of the camera and from said positions, using a computer, determining the coordinates of normal vectors (N 1, N 2) which are normal to two planes: - the first plane passing through the optical center and said two first points (P 1, P 2), and - the second plane passing through the optical center and the said two second points (P 3, P 4); and - the first plane passing through the optical center and said two first points (P 1, P 2), and - the second plane passing through the optical center and the said two second points (P 3, P 4); and c) using a computer, determining the coordinates of a vector collinear to said parallel vectors by calculating the vector product of said normal vectors (N 1, N 2).
A method of a multilayer transmission in a wireless network, comprising: generating, at a transmitter, a group of binary data bits for resources of each layer of a plurality of layers, wherein the resources are allocated or assigned among the plurality of layers, wherein the multi-layer transmission comprises four resources and six layers, wherein a number of resources used by each of the layers is two, and wherein the six layers are configured as three orthogonal pairs; mapping, at the transmitter, the group of binary data bits of each layer of the plurality of layers to respective code words in a signal constellation, wherein the mapping is based at least on maximizing a distance between the code words within each layer of the plurality of layers; combining, at the transmitter, the code words, wherein the code words associated with all the layers of a resource are combined to produce a combined code word for that resource; and transmitting, from the transmitter, the combined code word to a receiver in the wireless network; wherein the method further comprises rotating the signal constellation across the three orthogonal pairs for increasing distance between the code words of each of the plurality of layers. generating, at a transmitter, a group of binary data bits for resources of each layer of a plurality of layers, wherein the resources are allocated or assigned among the plurality of layers, wherein the multi-layer transmission comprises four resources and six layers, wherein a number of resources used by each of the layers is two, and wherein the six layers are configured as three orthogonal pairs; mapping, at the transmitter, the group of binary data bits of each layer of the plurality of layers to respective code words in a signal constellation, wherein the mapping is based at least on maximizing a distance between the code words within each layer of the plurality of layers; combining, at the transmitter, the code words, wherein the code words associated with all the layers of a resource are combined to produce a combined code word for that resource; and transmitting, from the transmitter, the combined code word to a receiver in the wireless network; wherein the method further comprises rotating the signal constellation across the three orthogonal pairs for increasing distance between the code words of each of the plurality of layers.
A dispensing apparatus for at least two flowable components having - a storage container having a first storage chamber for a first component with a first component outlet and having a second storage chamber for a second component with a second component outlet; - a closure element; and - a dispensing opening (31, 131), wherein - the storage chamber is rotatable with respect to the closure element; and - the storage container can adopt a closed position with respect to the closure element, in which closed position the component outlets (15, 16) are closed by the closure element and can adopt a dispensing position in which the component outlets (15, 16) are open and thus a dispensing of the components via the dispensing opening (31, 131) is possible and a change from the closed position into the dispensing position can be carried out by a rotation of the storage container with respect to the closure element, characterized in that the storage container and the closure element are designed in one piece in the closed position and are only connected to one another via connection webs, with the connection webs being designed such that they tear off on a rotation of the storage container from the closed position into the dispensing position. - a storage container having a first storage chamber for a first component with a first component outlet and having a second storage chamber for a second component with a second component outlet; - a closure element; and - a dispensing opening (31, 131), - the storage chamber is rotatable with respect to the closure element; and - the storage container can adopt a closed position with respect to the closure element, in which closed position the component outlets (15, 16) are closed by the closure element and can adopt a dispensing position in which the component outlets (15, 16) are open and thus a dispensing of the components via the dispensing opening (31, 131) is possible and a change from the closed position into the dispensing position can be carried out by a rotation of the storage container with respect to the closure element,
Combination of Bacillus Calmette Guerin with at least one COX-2 preferential FANS selected from the group consisting of meloxicam, nimesulide, tolfenamic, carprofen, etodolac, nabumetone.
A catalyst compound represented by Formula: wherein: M is a group 4 metal, preferably Hf; each of R 1, R 2, R 3, and R 4 is independently hydrogen, alkoxide, C 1 to C 40 substituted or unsubstituted hydrocarbyl, or -R 13 -SiR' 3 or -R 13 -CR' 3 where R 13 is C 1 to C 4 hydrocarbyl, and each R' is independently C 1 to C 20 substituted or unsubstituted hydrocarbyl; each of R 5, R 6, R 7, and R 8 is independently hydrogen, alkoxide, C 1 to C 40 substituted or unsubstituted hydrocarbyl, -R 13 -SiR' 3 or -R 13 -CR' 3 where R 13 is C 1 to C 4 hydrocarbyl, and each R' is independently C 1 to C 20 substituted or unsubstituted hydrocarbyl, or two or more of R 5, R 6, R 7, and R 8 form a substituted or unsubstituted, saturated, partially unsaturated or aromatic, cyclic or polycyclic substituent ring; wherein at least one of R 5, R 6, R 7, and R 8 is independently hydrogen, alkoxide, C 1 to C 40 substituted or unsubstituted hydrocarbyl, or -R 13 -SiR' 3 or -R 13 -CR' 3 -where R 13 is C 1 to C 4 hydrocarbyl, and each R' is independently C 1 to C 20 substituted or unsubstituted hydrocarbyl; wherein at least one of R 1, R 2, R 3, R 4, R 5, R 6, R 7, and R 8 is, -R 13 -SiR' 3 where R 13 is C 1 to C 4 hydrocarbyl, and each R' is independently C 1 to C 20 substituted or unsubstituted hydrocarbyl; each of X 1 and X 2 is independently a univalent anionic ligand, a diene ligand, an alkylidene ligand, or X 1 and X 2 are joined to form a metallocyclic ring; each of T 1 and T 2 is Si; each of R 9, R 10, R 11, and R 12 is independently a C 1 -C 20 containing hydrocarbyl. M is a group 4 metal, preferably Hf; each of R 1, R 2, R 3, and R 4 is independently hydrogen, alkoxide, C 1 to C 40 substituted or unsubstituted hydrocarbyl, or -R 13 -SiR' 3 or -R 13 -CR' 3 where R 13 is C 1 to C 4 hydrocarbyl, and each R' is independently C 1 to C 20 substituted or unsubstituted hydrocarbyl; each of R 5, R 6, R 7, and R 8 is independently hydrogen, alkoxide, C 1 to C 40 substituted or unsubstituted hydrocarbyl, -R 13 -SiR' 3 or -R 13 -CR' 3 where R 13 is C 1 to C 4 hydrocarbyl, and each R' is independently C 1 to C 20 substituted or unsubstituted hydrocarbyl, or two or more of R 5, R 6, R 7, and R 8 form a substituted or unsubstituted, saturated, partially unsaturated or aromatic, cyclic or polycyclic substituent ring; wherein at least one of R 5, R 6, R 7, and R 8 is independently hydrogen, alkoxide, C 1 to C 40 substituted or unsubstituted hydrocarbyl, or -R 13 -SiR' 3 or -R 13 -CR' 3 -where R 13 is C 1 to C 4 hydrocarbyl, and each R' is independently C 1 to C 20 substituted or unsubstituted hydrocarbyl; wherein at least one of R 1, R 2, R 3, R 4, R 5, R 6, R 7, and R 8 is, -R 13 -SiR' 3 where R 13 is C 1 to C 4 hydrocarbyl, and each R' is independently C 1 to C 20 substituted or unsubstituted hydrocarbyl; each of X 1 and X 2 is independently a univalent anionic ligand, a diene ligand, an alkylidene ligand, or X 1 and X 2 are joined to form a metallocyclic ring; each of T 1 and T 2 is Si; each of R 9, R 10, R 11, and R 12 is independently a C 1 -C 20 containing hydrocarbyl.
A fiber optic multiport, comprising: an enclosure defining an interior; a first chamber defined by the interior, wherein the first chamber comprises a plurality of optical fibers located therein, and wherein a potting material is disposed in the first chamber to physically secure the plurality of optical fibers in the first chamber; a second chamber defined by the interior adjacent the first chamber; a wall separating the first chamber from the second chamber, wherein the wall has a first face and a second face; a blocking material positioned adjacent to the wall to retain the potting material in the first chamber; characterized in that the wall has a plurality of slots extended therethrough from the first face to the second face, and wherein the plurality of optical fibers route through the plurality of slots between the first chamber and the second chamber and by a plurality of fiber organizers positioned in the second chamber, and wherein each of the plurality of fiber organizers comprises a first end and a second end, and wherein the plurality of fiber organizers press against the blocking material. an enclosure defining an interior; a first chamber defined by the interior, wherein the first chamber comprises a plurality of optical fibers located therein, and wherein a potting material is disposed in the first chamber to physically secure the plurality of optical fibers in the first chamber; a second chamber defined by the interior adjacent the first chamber; a wall separating the first chamber from the second chamber, wherein the wall has a first face and a second face; a blocking material positioned adjacent to the wall to retain the potting material in the first chamber; characterized in that the wall has a plurality of slots extended therethrough from the first face to the second face, and wherein the plurality of optical fibers route through the plurality of slots between the first chamber and the second chamber and by a plurality of fiber organizers positioned in the second chamber, and wherein each of the plurality of fiber organizers comprises a first end and a second end, and wherein the plurality of fiber organizers press against the blocking material.
A content adjustment method of a virtual reality device, wherein comprising: displaying a navigation control corresponding to a target object in a virtual reality scene; wherein the navigation control comprises a plurality of navigation areas successively arranged to form a rectangular structure, and wherein the target object is a target body in an output content of the virtual reality device, the target object comprises a plurality of object contents, and the plurality of navigation areas comprised in the navigation control are in one-to-one correspondence with the plurality of object contents; determining, according to a position change of a gaze point of a user in the navigation control, an initial position and an end moving position after the position change from the initial position; determining, based on the initial position and the end moving position, a change quantity and a change direction; and adjusting an object content of the target object in accordance with the change direction and the change quantity; and characterized in that the adjusting an object content of the target object in accordance with the change direction and the change quantity comprises: sequentially displaying, starting from the object content corresponding to the navigation area at the initial position, at least one object content in accordance with the change direction until the object content corresponding to the navigation area at the end moving position is displayed. displaying a navigation control corresponding to a target object in a virtual reality scene; wherein the navigation control comprises a plurality of navigation areas successively arranged to form a rectangular structure, and wherein the target object is a target body in an output content of the virtual reality device, the target object comprises a plurality of object contents, and the plurality of navigation areas comprised in the navigation control are in one-to-one correspondence with the plurality of object contents; determining, according to a position change of a gaze point of a user in the navigation control, an initial position and an end moving position after the position change from the initial position; determining, based on the initial position and the end moving position, a change quantity and a change direction; and adjusting an object content of the target object in accordance with the change direction and the change quantity; and characterized in that the adjusting an object content of the target object in accordance with the change direction and the change quantity comprises: sequentially displaying, starting from the object content corresponding to the navigation area at the initial position, at least one object content in accordance with the change direction until the object content corresponding to the navigation area at the end moving position is displayed.
A compound of formula for use in the treatment of trastuzumab emtansine refractory HER2 IHC 3+ or HER2 IHC 2+/FISH positive cancer patients, wherein 2.6-2.9 represent an average DAR for the compound.
An organic electroluminescent device comprising: a pair of electrodes; and an organic layer between the pair of electrodes, which comprises a light-emitting layer, wherein the organic layer contains a compound represented by the following formula; and the light-emitting layer contains a iridium complex phosphorescent material: wherein R 1, R 2, R 3, R 4, R 5, R 6, R 7 and R 8 each represents a hydrogen atom or a substituent, and contiguous substituents of R 1 to R 8 may be bonded to each other to form a condensed ring; R 9 represents an alkyl group, an alkenyl group, an aryl group, a hetero-aryl group, or a silyl group, and each of which group may be substituted with a substituent; and at least one of R 1 to R 9 represents a deuterium atom or a substituent containing a deuterium atom. a pair of electrodes; and an organic layer between the pair of electrodes, which comprises a light-emitting layer, wherein the organic layer contains a compound represented by the following formula; and the light-emitting layer contains a iridium complex phosphorescent material: wherein R 1, R 2, R 3, R 4, R 5, R 6, R 7 and R 8 each represents a hydrogen atom or a substituent, and contiguous substituents of R 1 to R 8 may be bonded to each other to form a condensed ring; R 9 represents an alkyl group, an alkenyl group, an aryl group, a hetero-aryl group, or a silyl group, and each of which group may be substituted with a substituent; and at least one of R 1 to R 9 represents a deuterium atom or a substituent containing a deuterium atom. R 1, R 2, R 3, R 4, R 5, R 6, R 7 and R 8 each represents a hydrogen atom or a substituent, and contiguous substituents of R 1 to R 8 may be bonded to each other to form a condensed ring; R 9 represents an alkyl group, an alkenyl group, an aryl group, a hetero-aryl group, or a silyl group, and each of which group may be substituted with a substituent; and at least one of R 1 to R 9 represents a deuterium atom or a substituent containing a deuterium atom.
A status display for the state of an operationally-relevant component of a motor vehicle, wherein an illuminating structure (4; 10; 11) supplied by at least two light sources (5, 6; LED 1....LED 4) is arranged in a position of the vehicle which is visible from the outside and the light sources are associated with a control circuit, which is designed to control the light sources in accordance with a state signal (sz) representing the state of the operationally-relevant component, such that the luminance and/or colour along the illuminating structure indicates the state of the component in a scale-like manner, characterised in that the illuminating structure has two or more light sources (5, 6; LED 1....LED 4) associated with the illuminating structure and the illuminating structure has at least one light stick having at least two light feed positions (A, B), which are each associated with the two or more light sources (5, 6), wherein the light stick is designed to guide the supplied light and to irradiate light on account of defects formed on the light stick, and the control circuit is designed to control the light sources at the two light feed positions in accordance with the state of the component.
A method of determining a ratio of drug to antibody in a sample comprising an antibody-drug conjugate, comprising: applying the sample to a size exclusion chromatography matrix; detecting absorbance of the sample at a first light wavelength (λ1), wherein the first wavelength is a predetermined absorbance maxima of the antibody; detecting absorbance of the sample at a second light wavelength (λ2), wherein the second wavelength is a predetermined absorbance maxima of the drug; determining the total absorbance of the sample at the first and second wavelengths, each total absorbance calculated by integrating peaks of absorbance responses over a time interval by summing an area of high molecular weight peaks, low molecular peaks and a main peak; and, calculating a DAR using the following Equation 1: DAR = ε λ 2 mAb ∗ Total Area λ 1 − ε λ 1 mAb ∗ Total Area λ 2 ε λ 1 drug ∗ Total Area λ 2 − ε λ 2 drug ∗ Total Area λ 1 wherein ε λ 1 mAb is an extinction coefficient of the antibody at the first wavelength; ε λ 2 mAb is an extinction coefficient of the antibody at the second wavelength; ε λ 1 drug is an extinction coefficient of the drug at the first wavelength; ε λ2 drug is an extinction coefficient of the drug at the second wavelength; Total Area λ1 is the total absorbance of the sample at the first wavelength; and Total Area λ2 is the total absorbance of the sample at the second wavelength. applying the sample to a size exclusion chromatography matrix; detecting absorbance of the sample at a first light wavelength (λ1), wherein the first wavelength is a predetermined absorbance maxima of the antibody; detecting absorbance of the sample at a second light wavelength (λ2), wherein the second wavelength is a predetermined absorbance maxima of the drug; determining the total absorbance of the sample at the first and second wavelengths, each total absorbance calculated by integrating peaks of absorbance responses over a time interval by summing an area of high molecular weight peaks, low molecular peaks and a main peak; and, calculating a DAR using the following Equation 1: DAR = ε λ 2 mAb ∗ Total Area λ 1 − ε λ 1 mAb ∗ Total Area λ 2 ε λ 1 drug ∗ Total Area λ 2 − ε λ 2 drug ∗ Total Area λ 1 wherein ε λ 1 mAb is an extinction coefficient of the antibody at the first wavelength; ε λ 2 mAb is an extinction coefficient of the antibody at the second wavelength; ε λ 1 drug is an extinction coefficient of the drug at the first wavelength; ε λ2 drug is an extinction coefficient of the drug at the second wavelength; Total Area λ1 is the total absorbance of the sample at the first wavelength; and Total Area λ2 is the total absorbance of the sample at the second wavelength.