mhurhangee/ep-ind-claims huggingface dataset:
An in vitro method for predicting responsiveness to a HER2-directed therapy by assessing HER2 heterogeneity in a tumor, the method comprising: • contacting a sample of the tumor with an antibody that specifically binds to HER2 protein and detecting HER2 protein in the sample, • contacting the sample of the tumor with a nucleic acid probe that specifically binds HER2 genomic DNA and detecting HER2 gene amplification status in the sample, • scoring the HER2 protein and HER2 gene (DISH), wherein scoring is categorized as: ∘ Group A for samples exhibiting IHC 3+ and DISH+, ∘ Group B for samples exhibiting IHC 3+ and DISH-, ∘ Group C for samples exhibiting IHC 2+ and DISH+, ∘ Group D for samples exhibiting IHC 2+ and DISH-, ∘ Group E for samples exhibiting IHC 0, 1+ and DISH+, and ∘ Group F for samples exhibiting IHC 0, 1+ and DISH-, • predicting that the tumor is responsive to the HER2-directed therapy if the tumor reveals a first foci having a first score being Group F and a second foci having a second score selected from Group A to Group E. • contacting a sample of the tumor with an antibody that specifically binds to HER2 protein and detecting HER2 protein in the sample, • contacting the sample of the tumor with a nucleic acid probe that specifically binds HER2 genomic DNA and detecting HER2 gene amplification status in the sample, • scoring the HER2 protein and HER2 gene (DISH), wherein scoring is categorized as: ∘ Group A for samples exhibiting IHC 3+ and DISH+, ∘ Group B for samples exhibiting IHC 3+ and DISH-, ∘ Group C for samples exhibiting IHC 2+ and DISH+, ∘ Group D for samples exhibiting IHC 2+ and DISH-, ∘ Group E for samples exhibiting IHC 0, 1+ and DISH+, and ∘ Group F for samples exhibiting IHC 0, 1+ and DISH-, ∘ Group A for samples exhibiting IHC 3+ and DISH+, ∘ Group B for samples exhibiting IHC 3+ and DISH-, ∘ Group C for samples exhibiting IHC 2+ and DISH+, ∘ Group D for samples exhibiting IHC 2+ and DISH-, ∘ Group E for samples exhibiting IHC 0, 1+ and DISH+, and ∘ Group F for samples exhibiting IHC 0, 1+ and DISH-, • predicting that the tumor is responsive to the HER2-directed therapy if the tumor reveals a first foci having a first score being Group F and a second foci having a second score selected from Group A to Group E.
A hydraulic boom recovery system for a mobile construction vehicle, comprising: a boom; a cylinder (21, 23) for powering the boom; an accumulator that is configured to recover potential energy from the cylinder pressure from the lowering of the boom; a pump that is configured to supply pressure to the cylinder (21, 23); and a sensor that is configured to sense an oncoming ground reaction between the boom and the ground; characterized in that, in response to the sensed reaction, the accumulator stops recovering and the pump provides pressure to the cylinder (21, 23) for the boom to dig into the ground. a boom; a cylinder (21, 23) for powering the boom; an accumulator that is configured to recover potential energy from the cylinder pressure from the lowering of the boom; a pump that is configured to supply pressure to the cylinder (21, 23); and a sensor that is configured to sense an oncoming ground reaction between the boom and the ground; characterized in that, in response to the sensed reaction, the accumulator stops recovering and the pump provides pressure to the cylinder (21, 23) for the boom to dig into the ground.
A computer-implemented spatial difference measurement method, comprising generating first key features of a first skeleton of a nominal 3D model of an object; extrapolating the first key features onto the nominal 3D model; creating an actual 3D model of the object during or after a construction process; generating second key features of a second skeleton of the actual 3D model of the object; extrapolating the second key features onto the actual 3D model of the object; and comparing the first key features extrapolated on the nominal 3D model to the second key features extrapolated on the actual 3D model to determine one or more distances between the first and second key features to measure a spatial difference between the nominal 3D model and the object during or after construction; and characterized by: further comprising receiving the nominal 3D model of an object, and generating the first skeleton based on the nominal 3D model, wherein the method includes generating the second skeleton based on the actual 3D model, wherein generating the first skeleton includes converting the nominal 3D model into a first finite element mesh using median axis method. generating first key features of a first skeleton of a nominal 3D model of an object; extrapolating the first key features onto the nominal 3D model; creating an actual 3D model of the object during or after a construction process; generating second key features of a second skeleton of the actual 3D model of the object; extrapolating the second key features onto the actual 3D model of the object; and comparing the first key features extrapolated on the nominal 3D model to the second key features extrapolated on the actual 3D model to determine one or more distances between the first and second key features to measure a spatial difference between the nominal 3D model and the object during or after construction; and characterized by: further comprising receiving the nominal 3D model of an object, and generating the first skeleton based on the nominal 3D model, wherein the method includes generating the second skeleton based on the actual 3D model, wherein generating the first skeleton includes converting the nominal 3D model into a first finite element mesh using median axis method.
A method of manufacturing an optical sheet, comprising: forming a single layer by feeding a curable resin composition; obtaining the single layer having a transferred nanopattern on a surface thereof by passing the single layer formed in through a release mold (1, 2) having a nanopattern having a pitch of 50 to 500 nm and an aspect ratio of 1.0 to 5.0; and curing the single layer having the transferred nanopattern obtained in, wherein the curable resin composition in comprises 100 parts by weight of a urethane acrylate having a weight average molecular weight of 100 to 30,000 and 75 to 250 parts by weight of a fluorine-containing siloxane-acrylate oligomer having a weight average molecular weight of 100 to 10,000 based on 100 parts by weight of the urethane acrylate. forming a single layer by feeding a curable resin composition; obtaining the single layer having a transferred nanopattern on a surface thereof by passing the single layer formed in through a release mold (1, 2) having a nanopattern having a pitch of 50 to 500 nm and an aspect ratio of 1.0 to 5.0; and curing the single layer having the transferred nanopattern obtained in,
A method, comprising: forming a trench through a first dielectric layer, a first conductive layer, and a second dielectric layer, the trench exposing a semiconductor substrate and dividing the first conductive layer into a first portion associated with a first word line driver and a second portion associated with a second word line driver; depositing a conformal material that contacts a first sidewall and a second sidewall of the trench such that the conformal material is formed in a plurality of recesses in the first conductive layer; forming an opening over a contact extending through the semiconductor substrate by etching a portion of the conformal material; and depositing, into the opening, a chalcogenide material configured to store information, the chalcogenide material in contact with a sidewall (390, 391) and a bottom wall of the opening and deposited so as to fill the recesses exposed by the etching, such that the conformal material fills the recesses on either side of the chalcogenide material that are not exposed by the etching. forming a trench through a first dielectric layer, a first conductive layer, and a second dielectric layer, the trench exposing a semiconductor substrate and dividing the first conductive layer into a first portion associated with a first word line driver and a second portion associated with a second word line driver; depositing a conformal material that contacts a first sidewall and a second sidewall of the trench such that the conformal material is formed in a plurality of recesses in the first conductive layer; forming an opening over a contact extending through the semiconductor substrate by etching a portion of the conformal material; and depositing, into the opening, a chalcogenide material configured to store information, the chalcogenide material in contact with a sidewall (390, 391) and a bottom wall of the opening and deposited so as to fill the recesses exposed by the etching, such that the conformal material fills the recesses on either side of the chalcogenide material that are not exposed by the etching.
A method of safe access control (500, 600), comprising: a) A room access control module of a hotel room determining that a user has presented an access credential; b) the room access control module reading the room and safe access information from the credential and determining privileges based thereon; c) in case of invalid room access information the room access control module maintaining room access control under secure conditions; d) in case of valid room access information, the room access control module determining if access to the safe within the room is allowed, using the safe access information; e) if access to the safe within the room is not allowed, the room access control module allowing access to the room, but not activating access to the safe; f) if access to the safe within the room is allowed the room access control module activating access to the safe by sending directly or wirelessly instructions to the safe access control module of an in-room safe to inform the safe access control module to allow access to the credential; g) the safe access control module determining that a user has presented an access credential; h) the safe access control module authenticating safe access based on the presented access credential by checking that both h1) the credential is allowed safe access and h2) access to the safe was activated by the room access control module. a) A room access control module of a hotel room determining that a user has presented an access credential; b) the room access control module reading the room and safe access information from the credential and determining privileges based thereon; c) in case of invalid room access information the room access control module maintaining room access control under secure conditions; d) in case of valid room access information, the room access control module determining if access to the safe within the room is allowed, using the safe access information; e) if access to the safe within the room is not allowed, the room access control module allowing access to the room, but not activating access to the safe; f) if access to the safe within the room is allowed the room access control module activating access to the safe by sending directly or wirelessly instructions to the safe access control module of an in-room safe to inform the safe access control module to allow access to the credential; g) the safe access control module determining that a user has presented an access credential; h) the safe access control module authenticating safe access based on the presented access credential by checking that both h1) the credential is allowed safe access and h2) access to the safe was activated by the room access control module.
A sanding machine for sanding/finishing/brushing components made of wood, metal or the like; each component having an upper face and a lower face, which are substantially parallel to one another, a front face and a rear face as well as two side faces; the sanding machine comprising a support structure (15, 16; 15, 16, 24); at least one sanding unit (12, 13); and a feeding device, which defines a support surface for at least one component and is designed to feed the component in a first direction, which is parallel to the support surface, and along a path extending through the sanding unit (12, 13); the sanding unit (12, 13) comprising, in turn, two conveyor assemblies (21, 22), which are mounted on opposite sides of the path in a second direction parallel to the support surface and transverse to the first direction, define a feeding channel feeding the component through the sanding unit (12, 13) and are movable relative to one another in the second direction depending on a width of the component measured parallel to the second direction; at least one conveyor assembly (21, 22) being provided with a sanding device for sanding/finishing/brushing a side face of the component; and being characterized in that at least one conveyor assembly (21, 22) comprises a rotary platform (31, 47), which is mounted so as to rotate around a rotation axis (32, 48), which is perpendicular to the support surface, due to the thrust exerted by the component upon the conveyor assembly (21, 22) depending on a profile of the side faces of the component.
A method for detecting a battery state of health, comprising performing distribution of relaxation times, DRT, processing on test data and obtaining a DRT spectrogram when performing an electrochemical impedance test on a power battery and obtaining the test data; determining peak parameters of at least some peaks among a plurality of peaks of the DRT spectrogram, wherein the peak parameters comprise a peak frequency and/or an integrated area of a peak; wherein the method is characterised by calculating deviations of the determined peak parameters from peak parameters of corresponding peaks in a DRT spectrogram corresponding to a reference power battery; determining a capacity loss rate corresponding to the calculated deviations according to a corresponding relationship between a predetermined deviation and a predetermined capacity loss rate of each of the plurality of peaks; and determining the battery state of health of the power battery according to the determined capacity loss rate. processing on test data and obtaining a DRT spectrogram when performing an electrochemical impedance test on a power battery and obtaining the test data; determining peak parameters of at least some peaks among a plurality of peaks of the DRT spectrogram, wherein the peak parameters comprise a peak frequency and/or an integrated area of a peak; wherein the method is characterised by calculating deviations of the determined peak parameters from peak parameters of corresponding peaks in a DRT spectrogram corresponding to a reference power battery; determining a capacity loss rate corresponding to the calculated deviations according to a corresponding relationship between a predetermined deviation and a predetermined capacity loss rate of each of the plurality of peaks; and determining the battery state of health of the power battery according to the determined capacity loss rate.
A crash box comprising a metal tubular body of a quadrangular basic cross-sectional shape having a pair of corner portions (32, 33) arranged oppositely and another pair of corner portions (34, 35) arranged to intersect at an angle of 80° or larger and 100° or smaller with respect to a line obtained by linking the pair of corner portions (32, 33), to receive an impact load from one end to the other end in an axial direction of the tubular body, wherein, on a cross section of the tubular body, an angle (θ 1) of the pair of corner portions (32, 33) is set to 90° or larger and 150° or smaller, an angle (θ 2) of said another pair of corner portions (34, 35) is set to 30° or larger and 90° or smaller, one or more inwardly convex trench portions extending in a longitudinal direction are provided in each of a pair of sides (36, 37; 38, 39) interposing at least either one of the pair of corner portions (32; 33), a cross-sectional peripheral length of the tubular body in the one end side is shorter than a cross-sectional peripheral length of the tubular body in the other end side, an aspect ratio between the longest one and the shortest one of diagonal lines of a polygon of the basic cross-sectional shape changes depending on a position on the axial direction of the tubular body, characterized in that opposite slope surfaces of the trench portions have different heights, defined by the length of an oblique side (36a, 36b; 37a, 37b; 38a, 38b; 39a, 39b) on the cross section, so that overall sides (46-1 - 46-22) on the cross section in the one end are formed in parallel to the opposite sides (47-1 - 47-22) on the cross section in the other end.
A method performed by either an unmanned aerial vehicle, UAV, or a remote control for the UAV, the remote control communicating with and controlling the UAV through control commands, for executing an operating session for the UAV in controlled airspace, wherein the method comprises the steps of: - transmitting a request for permission to operate in the controlled airspace to an airspace authority function; - receiving a reply to the request for permission to operate from the airspace authority function; and is characterized by performing the following steps if permission to operate is granted: - receiving a message comprising a protected ticket with information about a space-time region of airspace to operate in from the airspace authority function, the space-time region being defined as at least one portion of the controlled airspace varying with time and the protected ticket being encrypted or protected from tampering; - monitoring a position of the UAV in space and time; and - if the position of the UAV is within the space-time region and the UAV is either within a predetermined distance from a geographical border of the space-time region, or predicted to reach the geographical border of the space-time region within a predetermined time, activating, directly or after a predetermined time, assisted control of the UAV to assist an operator of the UAV in keeping the UAV within the space-time region. - transmitting a request for permission to operate in the controlled airspace to an airspace authority function; - receiving a reply to the request for permission to operate from the airspace authority function; and - receiving a message comprising a protected ticket with information about a space-time region of airspace to operate in from the airspace authority function, the space-time region being defined as at least one portion of the controlled airspace varying with time and the protected ticket being encrypted or protected from tampering; - monitoring a position of the UAV in space and time; and - if the position of the UAV is within the space-time region and the UAV is either within a predetermined distance from a geographical border of the space-time region, or predicted to reach the geographical border of the space-time region within a predetermined time, activating, directly or after a predetermined time, assisted control of the UAV to assist an operator of the UAV in keeping the UAV within the space-time region.
A method of authenticating a remote service to a user via a communications network, the method including: the remote service, using a computer, obtaining a service authentication code; communicating the service authentication code to the user via the communications network; and receiving or entering the service authentication code into an authentication device in the control of the user; wherein: the service authentication code is generated by a code generation algorithm based on a first secret key associated with the user, and the authentication device generates, using the code generation algorithm stored in memory on-board the authentication device, an expected code value based on a second secret key uniquely associated with the authentication device and stored in the memory of the authentication device and thereafter compares the expected code value to the service authentication code; and responsive to a comparison, and in the event that the expected code value correlates with the service authentication code, the authentication device generates a response that indicates to the user the authenticity of the remote service, wherein the first secret key is the same as the second secret key when the expected code value correlates with the service authentication code and the remote service is authentic. the remote service, using a computer, obtaining a service authentication code; communicating the service authentication code to the user via the communications network; and receiving or entering the service authentication code into an authentication device in the control of the user; the service authentication code is generated by a code generation algorithm based on a first secret key associated with the user, and the authentication device generates, using the code generation algorithm stored in memory on-board the authentication device, an expected code value based on a second secret key uniquely associated with the authentication device and stored in the memory of the authentication device and thereafter compares the expected code value to the service authentication code; and responsive to a comparison, and in the event that the expected code value correlates with the service authentication code, the authentication device generates a response that indicates to the user the authenticity of the remote service,
A pneumatic tire in which at least one main groove is formed in each tread portion on either side of a tire equator S to form a plurality of land portions (14, 15, 16), and a microgroove that extends in a width direction and closes at a time of grounding, and a crossing microgroove that crosses the microgroove and closes at the time of grounding, are formed in at least one of the land portions (14, 15, 16), such that block groups, each consisting of a plurality of blocks aligned along the microgroove, are arranged in the at least one of the land portions (14, 15, 16) repeatedly in a circumferential direction, wherein widthwise sidewalls of blocks in a block group arranged adjacent to each other in a circumferential direction are displaced from each other along the microgroove by a distance L corresponding to from 1/3 to 1/2 of an arrangement pitch P of the blocks, the arrangement pitch P being the distance between the same points in blocks adjacent to each other in the width direction, and is a value measured along the existing direction of a microgroove, wherein a groove depth D of the microgroove and the crossing microgroove formed in the at least one of the land portions (14, 15, 16) is larger than a groove depth F of a main groove that comes into contact with the land portion (14, 15, 16) at a widthwise outer side.