Combustion engine, - with a fresh air side and an exhaust gas side, - with a fresh air line communicating with the fresh air side and with an exhaust gas line communicating with the exhaust gas side - with a first exhaust gas turbocharger which has a first turbine wheel and a first compressor wheel which is connected thereto in a rotationally fixed manner via a first shaft, wherein the first turbine wheel is arranged in the exhaust gas line and the first compressor wheel in the fresh air line, - with a second exhaust gas turbocharger, which has a second turbine wheel and a second compressor wheel connected thereto in a rotationally fixed manner via a second shaft, - wherein the second turbine wheel is arranged in the exhaust gas line between the exhaust gas side and the first turbine wheel and the second compressor wheel is arranged in the fresh air line between the fresh air side and the first compressor wheel, - wherein the second compressor wheel is arranged in a housing interior which is partially delimited by a compressor housing of the second exhaust gas turbocharger, and wherein the second shaft is rotatably mounted on a bearing housing of the second exhaust gas turbocharger, - wherein a flow channel for the fresh air conducted through the fresh air line is delimited by the compressor housing, the second compressor wheel and the bearing housing of the second exhaust gas turbocharger characterised in that - thermal insulation is provided between the bearing housing and the compressor housing of the second exhaust gas turbocharger to reduce heat transfer from the bearing housing to the compressor housing, the thermal insulation being formed on a side of the bearing housing facing the flow channel, - in the first exhaust gas turbocharger, no thermal insulation is provided between its compressor housing and its bearing housing. - with a fresh air side and an exhaust gas side, - with a fresh air line communicating with the fresh air side and with an exhaust gas line communicating with the exhaust gas side - with a first exhaust gas turbocharger which has a first turbine wheel and a first compressor wheel which is connected thereto in a rotationally fixed manner via a first shaft, wherein the first turbine wheel is arranged in the exhaust gas line and the first compressor wheel in the fresh air line, - with a second exhaust gas turbocharger, which has a second turbine wheel and a second compressor wheel connected thereto in a rotationally fixed manner via a second shaft, - wherein the second turbine wheel is arranged in the exhaust gas line between the exhaust gas side and the first turbine wheel and the second compressor wheel is arranged in the fresh air line between the fresh air side and the first compressor wheel, - wherein the second compressor wheel is arranged in a housing interior which is partially delimited by a compressor housing of the second exhaust gas turbocharger, and wherein the second shaft is rotatably mounted on a bearing housing of the second exhaust gas turbocharger, - wherein a flow channel for the fresh air conducted through the fresh air line is delimited by the compressor housing, the second compressor wheel and the bearing housing of the second exhaust gas turbocharger characterised in that - thermal insulation is provided between the bearing housing and the compressor housing of the second exhaust gas turbocharger to reduce heat transfer from the bearing housing to the compressor housing, the thermal insulation being formed on a side of the bearing housing facing the flow channel, - in the first exhaust gas turbocharger, no thermal insulation is provided between its compressor housing and its bearing housing.