An oil fraction that has anti-inflammatory or resolution-stimulating activity, enriched with Specialized Proresolving Mediator precursors, wherein the SPM precursors originate from an oil obtained from organisms containing long chain omega-3 polyunsaturated fatty acids, wherein the SPM precursors are: 11S-HEPE (11S-hydroxy-eicosa-SZ,8Z,12E,14Z,17Z-pentaenoic acid); 12S-HEPE (12S-hydroxy-eicosa-5Z,8Z,10E,14Z,17Z-pentaenoic acid); 12R-HEPE (12R-hydroxy-eicosa-5Z, 8Z,10E,14Z,17Z-pentaenoic acid); 15S-HEPE (15S-hydroxy-eicosa-5Z,8Z,11Z,13E,17Z-pentaenoic acid); 18S-HEPE (18S-hydroxy-eicosa-5Z,8Z,11Z,14Z,16E-pentaenoic acid); 18R-HEPE (18R-hydroxy-eicosa-5Z,8Z,11Z,14Z,16E-pentaenoic acid); 4S-HDHA (4S-hydroxy-docosa-5E,7Z,10Z,13Z,16Z,19Z-hexaenoic acid); 7S-HDHA (7S-hydroxy- docosa-4Z,8E,10Z,13Z,16Z,19Z-hexaenoic acid); 10S-HDHA (10S-hydroxy-docosa-4Z,7Z,11E,13Z,16Z,19Z-hexaenoic acid); 11S-HDHA (11S-hydroxy-docosa-4Z,7Z,9E,13Z,16Z,19Z-hexaenoic acid); 14S-HDHA (14S-hydroxy-docosa-4Z,7Z,10Z,12E,16Z,19Z-hexaenoic acid); 14R-HDHA (14R-hydroxy-docosa-4Z,7Z,10Z,12E,16Z,19Z-hexaenoic acid); 17S-HDHA (17S-hydroxy-docosa-4Z,7Z,10Z,13Z,15E,19Z-hexaenoic acid); 17R-HDHA (17R-hydroxy-docosa-4Z,7Z,10Z,13Z,15E,19Z-hexaenoic acid); 20S-HDHA (20S-hydroxy-docosa-4Z,7Z,10Z,13Z,16Z,18E-hexaenoic acid); 17S-HDPAn- 6 (17S-hydroxy-docosa-4Z,7Z,10Z,13Z,15E-pentaenoic acid); 14S-HDPAn- 6 (14S-hydroxy-docosa-4Z,7Z, 10Z, 12E,16Z-pentaenoic acid); 10S-HDPAn- 6 (10 S-hydroxy-docosa-4Z,7Z,11E,13Z,16Z-pentaenoic acid); 17S-HDPAn- 3 (17S-hydroxy-docosa-7Z,10Z,13Z,15E,19Z-pentaenoic acid); 14S-HDPAn- 3 (14S-hydroxy-docosa-7Z, 10Z, 12E, 16Z, 19Z-pentaenoic acid); 10S-HDPAn- 3 (10S-hydroxy-docosa-7Z,11E,13Z,16Z,19Z-pentaenoic acid); 15S-HETE (15S-hydroxy-eicosa-5Z,8Z,11Z,13E-tetraenoic acid); and 15R-HETE (15R-hydroxy-eicosa5Z,8Z,11Z,13E-tetraenoic acid). 11S-HEPE (11S-hydroxy-eicosa-SZ,8Z,12E,14Z,17Z-pentaenoic acid); 12S-HEPE (12S-hydroxy-eicosa-5Z,8Z,10E,14Z,17Z-pentaenoic acid); 12R-HEPE (12R-hydroxy-eicosa-5Z, 8Z,10E,14Z,17Z-pentaenoic acid); 15S-HEPE (15S-hydroxy-eicosa-5Z,8Z,11Z,13E,17Z-pentaenoic acid); 18S-HEPE (18S-hydroxy-eicosa-5Z,8Z,11Z,14Z,16E-pentaenoic acid); 18R-HEPE (18R-hydroxy-eicosa-5Z,8Z,11Z,14Z,16E-pentaenoic acid); 4S-HDHA (4S-hydroxy-docosa-5E,7Z,10Z,13Z,16Z,19Z-hexaenoic acid); 7S-HDHA (7S-hydroxy- docosa-4Z,8E,10Z,13Z,16Z,19Z-hexaenoic acid); 10S-HDHA (10S-hydroxy-docosa-4Z,7Z,11E,13Z,16Z,19Z-hexaenoic acid); 11S-HDHA (11S-hydroxy-docosa-4Z,7Z,9E,13Z,16Z,19Z-hexaenoic acid); 14S-HDHA (14S-hydroxy-docosa-4Z,7Z,10Z,12E,16Z,19Z-hexaenoic acid); 14R-HDHA (14R-hydroxy-docosa-4Z,7Z,10Z,12E,16Z,19Z-hexaenoic acid); 17S-HDHA (17S-hydroxy-docosa-4Z,7Z,10Z,13Z,15E,19Z-hexaenoic acid); 17R-HDHA (17R-hydroxy-docosa-4Z,7Z,10Z,13Z,15E,19Z-hexaenoic acid); 20S-HDHA (20S-hydroxy-docosa-4Z,7Z,10Z,13Z,16Z,18E-hexaenoic acid); 17S-HDPAn- 6 (17S-hydroxy-docosa-4Z,7Z,10Z,13Z,15E-pentaenoic acid); 14S-HDPAn- 6 (14S-hydroxy-docosa-4Z,7Z, 10Z, 12E,16Z-pentaenoic acid); 10S-HDPAn- 6 (10 S-hydroxy-docosa-4Z,7Z,11E,13Z,16Z-pentaenoic acid); 17S-HDPAn- 3 (17S-hydroxy-docosa-7Z,10Z,13Z,15E,19Z-pentaenoic acid); 14S-HDPAn- 3 (14S-hydroxy-docosa-7Z, 10Z, 12E, 16Z, 19Z-pentaenoic acid); 10S-HDPAn- 3 (10S-hydroxy-docosa-7Z,11E,13Z,16Z,19Z-pentaenoic acid); 15S-HETE (15S-hydroxy-eicosa-5Z,8Z,11Z,13E-tetraenoic acid); and 15R-HETE (15R-hydroxy-eicosa5Z,8Z,11Z,13E-tetraenoic acid).