mhurhangee/ep-ind-claims huggingface dataset:
A heterodimeric, conditionally active chimeric antigen receptor comprising: a) a first polypeptide comprising: i) a first member of a specific binding pair; ii) a first co-stimulatory domain; iii) a first member of a dimerization pair; and iv) a transmembrane domain interposed between the first member of a specific binding pair and the first co-stimulatory domain; and b) a second polypeptide comprising: i) a transmembrane domain; ii) a second co-stimulatory domain; iii) a second member of the dimerization pair; and iv) an intracellular signaling domain; or comprising: a) a first polypeptide comprising: i) a first member of a specific binding pair; ii) a co-stimulatory domain; iii) a first member of a dimerization pair; iv) a transmembrane domain interposed between the first member of a specific binding pair and the co-stimulatory domain; and b) a second polypeptide comprising: i) a second member of the dimerization pair; and ii) an intracellular signaling domain, wherein the first and second members of the dimerization pair form a homodimer or a heterodimer in the presence of a dimerizing agent. a) a first polypeptide comprising: i) a first member of a specific binding pair; ii) a first co-stimulatory domain; iii) a first member of a dimerization pair; and iv) a transmembrane domain interposed between the first member of a specific binding pair and the first co-stimulatory domain; and i) a first member of a specific binding pair; ii) a first co-stimulatory domain; iii) a first member of a dimerization pair; and iv) a transmembrane domain interposed between the first member of a specific binding pair and the first co-stimulatory domain; and b) a second polypeptide comprising: i) a transmembrane domain; ii) a second co-stimulatory domain; iii) a second member of the dimerization pair; and iv) an intracellular signaling domain; i) a transmembrane domain; ii) a second co-stimulatory domain; iii) a second member of the dimerization pair; and iv) an intracellular signaling domain; a) a first polypeptide comprising: i) a first member of a specific binding pair; ii) a co-stimulatory domain; iii) a first member of a dimerization pair; iv) a transmembrane domain interposed between the first member of a specific binding pair and the co-stimulatory domain; and i) a first member of a specific binding pair; ii) a co-stimulatory domain; iii) a first member of a dimerization pair; iv) a transmembrane domain interposed between the first member of a specific binding pair and the co-stimulatory domain; and b) a second polypeptide comprising: i) a second member of the dimerization pair; and ii) an intracellular signaling domain, i) a second member of the dimerization pair; and ii) an intracellular signaling domain,
A method of preparing an aqueous urea-formaldehyde resin with formaldehyde-to-urea (F/U) mole ratio of from 0.7 to 1.15 and suitable for use in bonding lignocellulosic materials, which comprises: a) mixing water with a urea-formaldehyde pre-condensate or formaldehyde solution at a temperature of between 25-30°C under stirring to provide a mixture and adjusting the pH value of said mixture to from 5.2 to 6.5 b) adding urea to the mixture to obtain a formaldehyde to urea (F/U) mole ratio of from 2.3 to 3.5:1.0 and heating said mixture to a temperature of 50-85°C c) adjusting the pH of said mixture to 2.0-5.7 and incrementally adding urea to said mixture to facilitate a two or three stage polymerisation reaction to provide a formaldehyde to urea mole ratio of from 1.95 to 1.4 d) increasing the pH of said resin such that it is slightly alkaline to terminate polymerisation upon reaching a desired viscosity or water tolerance and optionally adding a further amount of urea and/or urea-formaldehyde pre-condensate to said resin and maintaining the resin for a certain time at a temperature of 50-85°C e) optionally adding a final amount of urea to said resin, to attain the desired final formaldehyde to urea mole ratio and allowing the methylolation to proceed and optionally applying vacuum distillation to obtain the desired level of resin solids, and f) cooling said resin to a temperature of 25-35°C and adjusting or maintaining the pH such that it is above 8.0. a) mixing water with a urea-formaldehyde pre-condensate or formaldehyde solution at a temperature of between 25-30°C under stirring to provide a mixture and adjusting the pH value of said mixture to from 5.2 to 6.5 b) adding urea to the mixture to obtain a formaldehyde to urea (F/U) mole ratio of from 2.3 to 3.5:1.0 and heating said mixture to a temperature of 50-85°C c) adjusting the pH of said mixture to 2.0-5.7 and incrementally adding urea to said mixture to facilitate a two or three stage polymerisation reaction to provide a formaldehyde to urea mole ratio of from 1.95 to 1.4 d) increasing the pH of said resin such that it is slightly alkaline to terminate polymerisation upon reaching a desired viscosity or water tolerance and optionally adding a further amount of urea and/or urea-formaldehyde pre-condensate to said resin and maintaining the resin for a certain time at a temperature of 50-85°C e) optionally adding a final amount of urea to said resin, to attain the desired final formaldehyde to urea mole ratio and allowing the methylolation to proceed and optionally applying vacuum distillation to obtain the desired level of resin solids, and f) cooling said resin to a temperature of 25-35°C and adjusting or maintaining the pH such that it is above 8.0.
A method for forming a nickel film comprising: disposing a solid electrolyte membrane between an anode and a substrate that functions as a cathode, bringing the solid electrolyte membrane into contact with the substrate, applying a voltage across the anode and the substrate and depositing nickel onto a surface of the substrate from nickel ions contained in the solid electrolyte membrane, thereby forming a nickel film containing the nickel on the surface of the substrate, bringing a nickel solution for forming a film into contact with the solid electrolyte membrane, thereby supplying the nickel ions to the solid electrolyte membrane, and applying a voltage across the anode and the substrate to form the nickel film on the surface of the substrate, the method characterized by a pH of the nickel solution for forming a film being in a range of 4.2 to 6.1, wherein the nickel solution for forming a film further contains a pH buffer solution, the pH buffer solution has a buffer function in the range of the pH and is an acetic acid-acetate buffer solution or a succinic acid-succinate buffer solution, and wherein cations contained in the pH buffer solution are nickel ions or ions of metal with lower ionization tendency than nickel. disposing a solid electrolyte membrane between an anode and a substrate that functions as a cathode, bringing the solid electrolyte membrane into contact with the substrate, applying a voltage across the anode and the substrate and depositing nickel onto a surface of the substrate from nickel ions contained in the solid electrolyte membrane, thereby forming a nickel film containing the nickel on the surface of the substrate, bringing a nickel solution for forming a film into contact with the solid electrolyte membrane, thereby supplying the nickel ions to the solid electrolyte membrane, and applying a voltage across the anode and the substrate to form the nickel film on the surface of the substrate, the method characterized by a pH of the nickel solution for forming a film being in a range of 4.2 to 6.1, wherein the nickel solution for forming a film further contains a pH buffer solution, the pH buffer solution has a buffer function in the range of the pH and is an acetic acid-acetate buffer solution or a succinic acid-succinate buffer solution, and wherein cations contained in the pH buffer solution are nickel ions or ions of metal with lower ionization tendency than nickel.
A corona discharge component, comprising: an ionization discharge cavity, which comprises a metal corona cylinder provided with an inlet of a to-be-analyzed gas and a trumpet-shaped front port which facilitates formation of a convergence electric field; and characterised by: multiple corona pins capable of independently controlling the on-off switching of high-voltage, which are insulatively mounted at the center of the metal corona cylinder; and a printed circuit board, PCB, for fixing the corona pins. multiple corona pins capable of independently controlling the on-off switching of high-voltage, which are insulatively mounted at the center of the metal corona cylinder; and a printed circuit board, PCB, for fixing the corona pins.
Device for weighing dough, comprising: - an endless conveyor, for conveying a plurality of endless dough pieces, extending essentially in parallel lanes on said conveyor in a direction of conveyance; - a plurality of weighing-units, arranged under the endless conveyor, and supporting the latter, the weighing units being distributed at different locations spread over the width of the conveyor, each for weighing a different dough piece, characterised in that the device comprises a plurality of cutting units downstream the weighing units, for cutting each of the parallel dough pieces. - an endless conveyor, for conveying a plurality of endless dough pieces, extending essentially in parallel lanes on said conveyor in a direction of conveyance; - a plurality of weighing-units, arranged under the endless conveyor, and supporting the latter, the weighing units being distributed at different locations spread over the width of the conveyor, each for weighing a different dough piece,
Connection chamber head configured to be buried in the ground while laid on a chamber in which may be housed means for connecting electric cable wires, for example particularly for low currents, or any other type of communication cable of an underground distribution network, which comprises a casing frame, a frame for receiving a plug for closing the chamber head, an inside peripheral hollow part configured to house the casing frame and the frame for receiving the plug resting on the casing frame and which comprises height adjustment members of the frame for receiving the plug when carried by the casing frame to position an upper edge of the frame for receiving the plug flush with the ground in which are buried the chamber and the chamber head, the height adjustment members being configured for the height adjustment of the frame relative to the bottom of the peripheral hollow part, in which the peripheral hollow part is delimited between an outer peripheral lateral wall and an upright peripheral inside wall itself delimiting the central opening of the chamber head able to communicate with the chamber, and the casing frame has in cross-section an L-shape, of which one of the peripheral branches is parallel to the bottom of the hollow part and serves as a mounting for the frame for receiving the plug and the other peripheral branch adjacent to the peripheral inside wall parallel thereto comprises a plurality of lugs projecting above the upper flat edge of the peripheral inside wall or above the bottom of the peripheral hollow part and which are passed through perpendicularly by the height adjustment members or comprise said height adjustment members under them.
An optical metrology system (200; 400; 1800; 2600) for measuring imperfections in a multi-focal volumetric light field generated by a display, the optical metrology system comprising: a display (208; 1802; 2500) configured to project a target light field comprising a virtual object having an intended focus position; a camera (1806; 2208) configured to obtain images of the target light field; a hardware processor (224; 228; 450; 1808; 2510; 2610) programmed with executable instructions to: access one or more images corresponding to a portion of the light field; analyze the one or more images to identify a measured focus position corresponding to a position at which the virtual object is in focus; and determine imperfections in the light field based at least in part on a comparison of the measured focus position and the intended focus position. a display (208; 1802; 2500) configured to project a target light field comprising a virtual object having an intended focus position; a camera (1806; 2208) configured to obtain images of the target light field; a hardware processor (224; 228; 450; 1808; 2510; 2610) programmed with executable instructions to: access one or more images corresponding to a portion of the light field; analyze the one or more images to identify a measured focus position corresponding to a position at which the virtual object is in focus; and determine imperfections in the light field based at least in part on a comparison of the measured focus position and the intended focus position. access one or more images corresponding to a portion of the light field; analyze the one or more images to identify a measured focus position corresponding to a position at which the virtual object is in focus; and determine imperfections in the light field based at least in part on a comparison of the measured focus position and the intended focus position.
A drive mechanism for a drug delivery device comprising - a housing, - a drive member, the drive member being configured to be axially displaced in a dose setting direction with respect to the housing for setting a dose of a drug and to be axially displaced in a dose delivery direction with respect to the housing for delivering the set dose of the drug, the drive member comprising a drive feature, - a piston rod assembly, the piston rod assembly comprising a set of interaction surfaces for mechanical interaction with the drive feature, with at least two interaction surfaces being axially and angularly offset with respect to each other, and characterized in that the drive mechanism is configured so that when the drive member is displaced in the dose delivery direction for delivering the set dose, the drive feature mechanically interacts with one of the interaction surfaces and the piston rod assembly rotates with respect to the housing, thereby rotating and axially displacing an other one of the interaction surfaces from a non-interaction position into an interaction position in which the drive feature may interact with the other one of the interaction surfaces when the drive mechanism is actuated once more for setting and delivering a further dose. - a housing, - a drive member, the drive member being configured to be axially displaced in a dose setting direction with respect to the housing for setting a dose of a drug and to be axially displaced in a dose delivery direction with respect to the housing for delivering the set dose of the drug, the drive member comprising a drive feature, - a piston rod assembly, the piston rod assembly comprising a set of interaction surfaces for mechanical interaction with the drive feature, with at least two interaction surfaces being axially and angularly offset with respect to each other, and characterized in that the drive mechanism is configured so that when the drive member is displaced in the dose delivery direction for delivering the set dose, the drive feature mechanically interacts with one of the interaction surfaces and the piston rod assembly rotates with respect to the housing, thereby rotating and axially displacing an other one of the interaction surfaces from a non-interaction position into an interaction position in which the drive feature may interact with the other one of the interaction surfaces when the drive mechanism is actuated once more for setting and delivering a further dose.
Motor vehicle door, in particular a handle-less motor vehicle side door, comprising • a door leaf, • at least one drive (12, 13), • an opening member connected to the drive (12, 13) for opening the door leaf at least partially with respect to a motor vehicle body, • the opening member being designed as a linear actuator which is arranged so as to be paraxial in relation to an axis of rotation of the door leaf; characterized in that • the opening member moves against the motor vehicle body in the extended position and thereby opens the door leaf at least partially; • the opening member does not abut the motor vehicle body in the retracted position. • a door leaf, • at least one drive (12, 13), • an opening member connected to the drive (12, 13) for opening the door leaf at least partially with respect to a motor vehicle body, • the opening member being designed as a linear actuator which is arranged so as to be paraxial in relation to an axis of rotation of the door leaf; characterized in that • the opening member moves against the motor vehicle body in the extended position and thereby opens the door leaf at least partially; • the opening member does not abut the motor vehicle body in the retracted position.
A system for the automatic manufacture of wind turbine blades, of the type having two die halves (2, 3) in which are molded two complementary "shells" whereby the attachment thereof determines the blade to be formed, each of the "shells" being formed in the respective die halves (2, 3) by a "cloth" determined by means of applying dry fiber mats to which the resin necessary for consolidation curing is incorporated after the application, the system having a gantry structure with head-bearing means (5, 6, 13) arranged with respect to the die halves (2, 3), said head-bearing means being susceptible to selectively having multi-nozzle demolding agent or paint application accessories, an adhesive application accessory, or a machining accessory,, and said head-bearing means determining a structural assembly capable of applying the "cloth" mats in the die halves (2, 3), the entire assembly operating automatically, characterized in that said gantry structure comprises: - a common gantry structure arranged above the assembly of the die halves (2, 3), in which common gantry structure heads (5, 6) are incorporated for operating each of said heads (5, 6) respectively on one of the die halves (2, 3) to selectively having said multi-nozzle demolding agent or paint application accessories, said adhesive application accessory or said machining accessory, there being in said common gantry structure itself deposits having the products to be applied by means of said heads (5, 6), and - respective individual gantry structures (11, 12) arranged above the die halves (2, 3), in each of which individual gantry structures two heads having identical structural formation but different widths are incorporated for applying therewith "cloth" mats of different widths in the respective die halves (2, 3). - a common gantry structure arranged above the assembly of the die halves (2, 3), in which common gantry structure heads (5, 6) are incorporated for operating each of said heads (5, 6) respectively on one of the die halves (2, 3) to selectively having said multi-nozzle demolding agent or paint application accessories, said adhesive application accessory or said machining accessory, there being in said common gantry structure itself deposits having the products to be applied by means of said heads (5, 6), and - respective individual gantry structures (11, 12) arranged above the die halves (2, 3), in each of which individual gantry structures two heads having identical structural formation but different widths are incorporated for applying therewith "cloth" mats of different widths in the respective die halves (2, 3).
A switching module for a chain link, the switching module comprising at least one switching cell (SC 1, SC 2), each switching cell (SC 1, SC 2) comprising a first side comprising a first terminal and a second terminal, a second side comprising a third terminal and a fourth terminal, a first switching unit, a second switching unit, and a first and a second capacitor unit (C1, C2), wherein - the first terminal is connected to the second terminal via the first capacitor unit, wherein the first capacitor unit is configured to have its positive side facing the first terminal, - the third terminal is connected to the fourth terminal via the second capacitor unit, wherein the second capacitor is configured to have its positive side facing the fourth terminal, and - the second terminal is connected to the fourth terminal via the second switching unit, characterized in comprising a third capacitor unit, wherein: - the first terminal is connected to the third terminal via a first series connection comprising the first switching unit and the third capacitor unit, wherein the third capacitor unit is configured to have its positive side facing the third terminal. - the first terminal is connected to the second terminal via the first capacitor unit, wherein the first capacitor unit is configured to have its positive side facing the first terminal, - the third terminal is connected to the fourth terminal via the second capacitor unit, wherein the second capacitor is configured to have its positive side facing the fourth terminal, and - the second terminal is connected to the fourth terminal via the second switching unit, - the first terminal is connected to the third terminal via a first series connection comprising the first switching unit and the third capacitor unit, wherein the third capacitor unit is configured to have its positive side facing the third terminal.
A method of data symbol recovery in a coherent receiver of an optical communications system, said method comprising: computing a phase rotation κ(n) which compensates a frequency offset Δf between a transmit laser and a Local Oscillator of the receiver; applying the phase rotation κ(n) to a plurality of data symbol estimates to generate corresponding rotated symbol estimates; and processing the rotated symbol estimates using a bounded filter function to generate corresponding decision values of each data symbol.; the method characterized by: processing two or more SYNC bursts having a known symbol sequence and periodicity such that the average phase error of each SYNC burst is zero in order to derive an estimate of a frequency offset Δf between a transmit laser and a Local Oscillator of the receiver; wherein the phase rotation κ(n) is computed based on the estimate of the frequency offset Δf. computing a phase rotation κ(n) which compensates a frequency offset Δf between a transmit laser and a Local Oscillator of the receiver; applying the phase rotation κ(n) to a plurality of data symbol estimates to generate corresponding rotated symbol estimates; and processing the rotated symbol estimates using a bounded filter function to generate corresponding decision values of each data symbol.; the method characterized by: processing two or more SYNC bursts having a known symbol sequence and periodicity such that the average phase error of each SYNC burst is zero in order to derive an estimate of a frequency offset Δf between a transmit laser and a Local Oscillator of the receiver; processing two or more SYNC bursts having a known symbol sequence and periodicity such that the average phase error of each SYNC burst is zero in order to derive an estimate of a frequency offset Δf between a transmit laser and a Local Oscillator of the receiver;