A compound of Formula 1 or Formula 2, a pharmaceutically acceptable salt thereof or an optical isomer thereof: wherein R 1 is -H, linear or branched C 1-3 alkyl, or -NO 2; R 2 is -NH 2; R 3 is -H or linear or branched C 1-3 alkyl; R 4a, R 4b, R 4c and R 4d are independently -H or linear or branched C 1-4 alkyl; X is -O-, -NH-, or -NR 6 -, wherein R 6 is linear or branched C 1-3 alkyl; L is a single bond, wherein R 11 is O, NH, or S, and wherein a, b, c, d, and e are independently integers of 0-3; R 5 is -CN; linear or branched C 1-8 alkyl; linear or branched C 1-8 haloalkyl; phenyl; phenyl linear or branched C 1-3 alkyl; phenyl linear or branched C 1-3 alkenyl; 5-6 atom heteroaryl including one or more heteroatoms of one or more species selected from a group consisting of N, O and S; 5-6 atom heterocycloalkyl including one or more heteroatoms of one or more species selected from a group consisting of N, O and S; 5-6 atom heterocycloalkenyl including one or more heteroatoms of one or more species selected from a group consisting of N, O and S; or wherein the phenyl group in the phenyl, phenyl linear or branched C 1-3 alkyl, and phenyl linear or branched C 1-3 alkenyl, may be substituted with one or more substituents of one or more species selected from a group consisting of -OH, halogen, linear or branched C 1-3 alkyl, linear or branched C 1-3 alkoxy, and -NO 2, wherein the heteroaryl, heterocycloalkyl, and heterocycloalkenyl may be substituted with one or more species selected from a group consisting of -OH, halogen, and linear or branched C 1-3 alkyl; R 7 and R 3 are independently -H, linear or branched C 1-4 alkyl, unsubstituted phenyl, or phenyl substituted with one or more linear or branched C 1-3 alkyl, R 9, R 10, and R 11 are independently -H, or linear or branched C 1-6 alkyl, Z is -O- or -S-, and f, g, h and i are independently integers of 0-3. R 1 is -H, linear or branched C 1-3 alkyl, or -NO 2; R 2 is -NH 2; R 3 is -H or linear or branched C 1-3 alkyl; R 4a, R 4b, R 4c and R 4d are independently -H or linear or branched C 1-4 alkyl; X is -O-, -NH-, or -NR 6 -, wherein R 6 is linear or branched C 1-3 alkyl; L is a single bond, wherein R 11 is O, NH, or S, and wherein a, b, c, d, and e are independently integers of 0-3; R 5 is -CN; linear or branched C 1-8 alkyl; linear or branched C 1-8 haloalkyl; phenyl; phenyl linear or branched C 1-3 alkyl; phenyl linear or branched C 1-3 alkenyl; 5-6 atom heteroaryl including one or more heteroatoms of one or more species selected from a group consisting of N, O and S; 5-6 atom heterocycloalkyl including one or more heteroatoms of one or more species selected from a group consisting of N, O and S; 5-6 atom heterocycloalkenyl including one or more heteroatoms of one or more species selected from a group consisting of N, O and S; or wherein the phenyl group in the phenyl, phenyl linear or branched C 1-3 alkyl, and phenyl linear or branched C 1-3 alkenyl, may be substituted with one or more substituents of one or more species selected from a group consisting of -OH, halogen, linear or branched C 1-3 alkyl, linear or branched C 1-3 alkoxy, and -NO 2, wherein the heteroaryl, heterocycloalkyl, and heterocycloalkenyl may be substituted with one or more species selected from a group consisting of -OH, halogen, and linear or branched C 1-3 alkyl; R 7 and R 3 are independently -H, linear or branched C 1-4 alkyl, unsubstituted phenyl, or phenyl substituted with one or more linear or branched C 1-3 alkyl, R 9, R 10, and R 11 are independently -H, or linear or branched C 1-6 alkyl, Z is -O- or -S-, and f, g, h and i are independently integers of 0-3.