A chemical compound having the general formula wherein R 1 is selected from the group consisting of phenyl, thienyl, furyl, pyridyl, thiazolyl, oxazolyl and isoxazolyl, R 2 is alkyl, aryl, or aralkyl, M 1 is CH 2, M 2 is CO, M 3 is O, or S M 4 is CH 2, M 5 is (CR 11 R 12), wherein R 11 is hydrogen, R 12 is selected from the group consisting of NR 21 CONR 22 R 23, NR 21 COR 24, and NR 21 COOR 24,, R 21 and R 22, when present, are independently selected from the group consisting of hydrogen or C 1 -C 6 alkyl, R 23, when present, is selected from the group consisting of hydroxyalkyl, alkoxyalkyl, alkyl, aryl, aralkyl and alkoxycarbonylalkyl, R 24, when present, is selected from the group consisting of alkyl, and heterocyclyl, M 6 is (CH 2) q, wherein q is an integer from 0 to 6, R 3 is selected from the group consisting of hydrogen, NR 15 COOR 16, alkyl and aryl, wherein R 15, when present, is hydrogen or C 1 -C 6 alkyl, R 16, when present, is selected from the group consisting of alkyl, and aralkyl, and R 1 and R 2 may independently be either unsubstituted or substituted with one or more substituents selected from the group consisting of alkyl, hydroxy, alkoxy, azido, haloalkoxy,halo, haloalkyl, amino, alkylamino, dialkylamino, and R 3 may be either unsubstituted or substituted with one or more substituents selected from the group consisting of alkyl, aryl, aralkyl, hydroxy, alkoxy, haloalkoxy, hydroxyalkyl, hydroxyaryl, alkoxyaryl, halo, amino, alkylamino, dialkylamino, -NHCO(alkyl), -NHCO(aryl), -NHCO(aralkyl), -NHCO(haloalkyl), - NHSO 2 (alkyl), -NHSO 2 (aryl), -NHSO 2 (aralkyl), alkoxycarbonyl, wherein the term "aryl" refers to a carbocyclic aromatic group having 6 to 12 carbon atoms or a heterocyclic aromatic group, and wherein the term "aralkyl" refers to an aryl substituted alkyl radical, wherein the term "aryl" is as defined above. R 1 is selected from the group consisting of phenyl, thienyl, furyl, pyridyl, thiazolyl, oxazolyl and isoxazolyl, R 2 is alkyl, aryl, or aralkyl, M 1 is CH 2, M 2 is CO, M 3 is O, or S M 4 is CH 2, M 5 is (CR 11 R 12), wherein R 11 is hydrogen, R 12 is selected from the group consisting of NR 21 CONR 22 R 23, NR 21 COR 24, and NR 21 COOR 24,, R 21 and R 22, when present, are independently selected from the group consisting of hydrogen or C 1 -C 6 alkyl, R 23, when present, is selected from the group consisting of hydroxyalkyl, alkoxyalkyl, alkyl, aryl, aralkyl and alkoxycarbonylalkyl, R 24, when present, is selected from the group consisting of alkyl, and heterocyclyl, M 6 is (CH 2) q, wherein q is an integer from 0 to 6, R 3 is selected from the group consisting of hydrogen, NR 15 COOR 16, alkyl and aryl, wherein R 15, when present, is hydrogen or C 1 -C 6 alkyl, R 16, when present, is selected from the group consisting of alkyl, and aralkyl, and R 1 and R 2 may independently be either unsubstituted or substituted with one or more substituents selected from the group consisting of alkyl, hydroxy, alkoxy, azido, haloalkoxy,halo, haloalkyl, amino, alkylamino, dialkylamino, and R 3 may be either unsubstituted or substituted with one or more substituents selected from the group consisting of alkyl, aryl, aralkyl, hydroxy, alkoxy, haloalkoxy, hydroxyalkyl, hydroxyaryl, alkoxyaryl, halo, amino, alkylamino, dialkylamino, -NHCO(alkyl), -NHCO(aryl), -NHCO(aralkyl), -NHCO(haloalkyl), - NHSO 2 (alkyl), -NHSO 2 (aryl), -NHSO 2 (aralkyl), alkoxycarbonyl, wherein the term "aryl" refers to a carbocyclic aromatic group having 6 to 12 carbon atoms or a heterocyclic aromatic group, and wherein the term "aralkyl" refers to an aryl substituted alkyl radical, wherein the term "aryl" is as defined above.