mhurhangee/ep-ind-claims huggingface dataset:
An isolated monoclonal antibody or antigen binding fragment thereof comprising a heavy chain variable domain and a light chain variable domain, wherein the heavy chain variable domain comprises a heavy chain complementarity determining region (HCDR)1, an HCDR2 and an HCDR3, and wherein the light chain variable domain comprises a light chain complementarity determining region (LCDR)1, an LCDR2 and an LCDR3, wherein the heavy chain variable domain comprises the HCDR1, HCDR2 and HCDR3 of SEQ ID NO: 1 as determined using a method of Paratome, Kabat, Chothia or IMGT, and wherein the light chain variable domain comprises the LCDR1, LCDR2 and LCDR3 of SEQ ID NO: 2, as determined using the method of Paratome, Kabat, Chothia or IMGT, and wherein the HCDR1, HCDR2, HCDR3, LCDR1, LCDR2 and LCDR3 are determined using the same method, and wherein the monoclonal antibody specifically binds emtricitabine. wherein the heavy chain variable domain comprises a heavy chain complementarity determining region (HCDR)1, an HCDR2 and an HCDR3, and wherein the light chain variable domain comprises a light chain complementarity determining region (LCDR)1, an LCDR2 and an LCDR3, wherein the heavy chain variable domain comprises the HCDR1, HCDR2 and HCDR3 of SEQ ID NO: 1 as determined using a method of Paratome, Kabat, Chothia or IMGT, and wherein the light chain variable domain comprises the LCDR1, LCDR2 and LCDR3 of SEQ ID NO: 2, as determined using the method of Paratome, Kabat, Chothia or IMGT, and wherein the HCDR1, HCDR2, HCDR3, LCDR1, LCDR2 and LCDR3 are determined using the same method, and wherein the monoclonal antibody specifically binds emtricitabine.
A method of forming a capacitor tank comprising a cured seal between an insulating bushing and a metallic tank cover, comprising the steps of: a. applying an epoxy resin composition to a portion of one or both of the insulating bushing and the metallic tank cover; b. contacting the insulating bushing to the metallic tank cover such that the epoxy resin composition forms a seal between the insulating bushing and the metallic tank cover; c. curing the seal to form the cured seal; and d. attaching the tank cover with the sealed insulating bushing to a casing of the capacitor tank, the capacitor tank to contain a fluid comprising one or more aromatic compounds, wherein the insulating bushing comprises substantially glass, ceramic, polymer or glazed material; wherein the epoxy resin composition comprises: a phenol novolac epoxy, a bisphenol A epoxy, or a combination thereof, and a curing agent; wherein the curing agent is an amine-containing hardener or cyanamide or dicyandiamide; wherein the cured seal withstands exposure to the fluid comprising one or more aromatic compounds; and wherein the capacitor tank complies with one or more of International Electrotechnical Commission standard 60871-1:2005, Section 12 and Institute of Electrical and Electronics Engineers standard 18:2012, Section 7.2.3. a. applying an epoxy resin composition to a portion of one or both of the insulating bushing and the metallic tank cover; b. contacting the insulating bushing to the metallic tank cover such that the epoxy resin composition forms a seal between the insulating bushing and the metallic tank cover; c. curing the seal to form the cured seal; and d. attaching the tank cover with the sealed insulating bushing to a casing of the capacitor tank, the capacitor tank to contain a fluid comprising one or more aromatic compounds,
Method for the in-vitro diagnosis and/or in-vitro therapy monitoring of tuberculosis and/or borreliosis for differentiation between acute (active) infections on the one hand and latent (chronic) or overcome infections on the other hand, characterized in that eukaryotic cells are incubated with at least one tuberculosis specific antigen and/or at least one borreliosis specific antigen and tested for cells (ASCs) secreting antigen-specific antibodies, the secreted antibodies of which are directed specifically against the antigen, wherein incubation of the eukaryotic cells is for a time period between 2 and 18 hours.
End piece suitable for forming a spacer for a roll consisting of two concentric tubes (10, 11) with axis xx' and comprising spokes connecting two inner and outer cylindrical portions, characterized in that a fluid circuit originating from the centre towards the periphery comprises a first circumferential groove arranged in the inner cylindrical portion and a second circumferential groove arranged in the outer cylindrical portion connected by at least one pipe.
A transparent and essentially colorless and non-diffusing glass-ceramic of the lithium aluminosilicate type containing a β-quartz solid solution as main crystalline phase, wherein: - its composition, free of arsenic oxide, antimony oxide and rare earth oxide except for inevitable trace amounts, contains, expressed as percentages by weight of oxides: 62-72% of SiO 2, 20-23% of Al 2 O 3, 2.8-5% of Li 2 O, 0.1-0.6% of SnO 2, 1.9-4% of TiO 2, 1.6-3% of ZrO 2, less than 0.4% of MgO, 0.4-3% of ZnO and 2.1-5% of BaO, with 2.5-6% of ZnO + BaO + SrO, less than 250 ppm of Fe 2 O 3; and - the crystallites present in said β-quartz solid solution have an average size of less than 35 nm, advantageously less than 30 nm. - its composition, free of arsenic oxide, antimony oxide and rare earth oxide except for inevitable trace amounts, contains, expressed as percentages by weight of oxides: 62-72% of SiO 2, 20-23% of Al 2 O 3, 2.8-5% of Li 2 O, 0.1-0.6% of SnO 2, 1.9-4% of TiO 2, 1.6-3% of ZrO 2, less than 0.4% of MgO, 0.4-3% of ZnO and 2.1-5% of BaO, with 2.5-6% of ZnO + BaO + SrO, less than 250 ppm of Fe 2 O 3; and 62-72% of SiO 2, 20-23% of Al 2 O 3, 2.8-5% of Li 2 O, 0.1-0.6% of SnO 2, 1.9-4% of TiO 2, 1.6-3% of ZrO 2, less than 0.4% of MgO, 0.4-3% of ZnO and 2.1-5% of BaO, with 2.5-6% of ZnO + BaO + SrO, less than 250 ppm of Fe 2 O 3; and - the crystallites present in said β-quartz solid solution have an average size of less than 35 nm, advantageously less than 30 nm.
A method of diagnosing a pump apparatus having a downhole pump disposed in a deviated wellbore and having motor at a surface of the deviated wellbore, the downhole pump reciprocated in the deviated wellbore by a rod string operatively moved by the motor, the method comprising: obtaining surface measurements indicative of surface load and surface position of the rod string at the surface; characterizing axial and transverse displacement of the rod string with two coupled non-linear differential equations of fourth order including an axial equation of motion and a transverse equation of motion; calculating initial axial displacement of the rod string by assuming there is no transverse displacement and by solving the axial equation of motion; calculating initial axial force using the initial axial displacement and assuming there is no transverse displacement; calculating initial transverse displacement of the rod string using the initial axial force and the initial axial displacement; calculating axial force and friction force using the initial axial and transverse displacements; calculating the axial displacement at the downhole pump by solving the axial equation of motion with the axial force and the friction force; calculating load at the downhole pump; and generating a downhole card representative of the load relative to the axial displacement of the downhole pump. obtaining surface measurements indicative of surface load and surface position of the rod string at the surface; characterizing axial and transverse displacement of the rod string with two coupled non-linear differential equations of fourth order including an axial equation of motion and a transverse equation of motion; calculating initial axial displacement of the rod string by assuming there is no transverse displacement and by solving the axial equation of motion; calculating initial axial force using the initial axial displacement and assuming there is no transverse displacement; calculating initial transverse displacement of the rod string using the initial axial force and the initial axial displacement; calculating axial force and friction force using the initial axial and transverse displacements; calculating the axial displacement at the downhole pump by solving the axial equation of motion with the axial force and the friction force; calculating load at the downhole pump; and generating a downhole card representative of the load relative to the axial displacement of the downhole pump.
A compound of Formula I: wherein each R 1 and R 2 is independently selected from the group consisting of H, halogen, C 1-6 alkyl, C 1-6 alkoxy, and C 1-6 haloalkyl; R 3 is selected from the group consisting of H, C 1-6 alkyl and C 3-8 cycloalkyl; X is selected from the group consisting of O, S and NH; Y is selected from the group consisting of O and NH; alternatively, R 1 or R 2 is combined with Y and the atoms to which they are attached to form a 5-membered heteroaryl ring; Z is a peptide having 3-20 independently selected amino acids, wherein at least one amino acid is selected from the group consisting of an unnatural amino acid and a D-amino acid; L is a linker; D is a bisphosphonate drug, wherein D has the formula: wherein R 4 is selected from the group consisting of H, OH and halogen; R 5 is selected from the group consisting of H and C 1-6 alkyl; and subscript t is from 1 to 6; subscripts m, n and q are each independently from 0 to 2; and salts and isomers thereof. wherein each R 1 and R 2 is independently selected from the group consisting of H, halogen, C 1-6 alkyl, C 1-6 alkoxy, and C 1-6 haloalkyl; R 3 is selected from the group consisting of H, C 1-6 alkyl and C 3-8 cycloalkyl; X is selected from the group consisting of O, S and NH; Y is selected from the group consisting of O and NH; alternatively, R 1 or R 2 is combined with Y and the atoms to which they are attached to form a 5-membered heteroaryl ring; Z is a peptide having 3-20 independently selected amino acids, wherein at least one amino acid is selected from the group consisting of an unnatural amino acid and a D-amino acid; L is a linker; D is a bisphosphonate drug, wherein D has the formula: wherein R 4 is selected from the group consisting of H, OH and halogen; R 5 is selected from the group consisting of H and C 1-6 alkyl; and subscript t is from 1 to 6; subscripts m, n and q are each independently from 0 to 2; and salts and isomers thereof.
Electronic control module for a motor vehicle electrical circuit, intended to be linked in a galvanically isolated manner to a motor vehicle electrical circuit comprising at least one functional module powered at high voltage, the control module comprising: - a connection bus, intended to be linked to an exterior interface, configured so as to conduct low-voltage electrical setpoint signals emanating from the exterior interface to the elements of the control module to which they are addressed, - a microcontroller, configured to control the at least one functional module as a function of the setpoint signals, characterized in that the microcontroller and the connection bus are linked by a non-galvanic coupler, provided with a low-voltage part and a high-voltage part, which are able to exchange at least one signal and are galvanically decoupled, and in that the control module furthermore comprises an electrical transformer, linked via outputs (153, 155, 157) to the high- and low-voltage parts (131, 133) of the non-galvanic coupler and to the microcontroller so as to provide their power supply, the transformer being linked to a source via a breaker switch, and the connection bus comprising a switching member controlling the open or closed state of the breaker switch. - a connection bus, intended to be linked to an exterior interface, configured so as to conduct low-voltage electrical setpoint signals emanating from the exterior interface to the elements of the control module to which they are addressed, - a microcontroller, configured to control the at least one functional module as a function of the setpoint signals,
A switch-containing cable comprising: a belt-like first conductor film including a first belt-like base material on an inner surface of which a first conductor is disposed; characterized by a belt-like second conductor film disposed oppositely to the first conductor film through a gap and including a second belt-like base material on an inner surface of which a second conductor is likewise disposed; an insulating spacer arranged between the second conductor film and the first conductor film to maintain a gap therebetween; and a belt-like sheath configured with the first and second conductor films between which the insulating spacer is held and containing a belt-like conductor film functioning as a switch member in a hollow cavity, wherein the first conductor film constituting the belt-like conductor film is movably overlaid on the insulating spacer, and the hollow cavity of the sheath includes a gap which allows for the lengthwise relative displacement of at least the first belt-like base material caused by bending the sheath with respect to the belt-like conductor film housed in the hollow cavity. a belt-like first conductor film including a first belt-like base material on an inner surface of which a first conductor is disposed; characterized by a belt-like second conductor film disposed oppositely to the first conductor film through a gap and including a second belt-like base material on an inner surface of which a second conductor is likewise disposed; an insulating spacer arranged between the second conductor film and the first conductor film to maintain a gap therebetween; and a belt-like sheath configured with the first and second conductor films between which the insulating spacer is held and containing a belt-like conductor film functioning as a switch member in a hollow cavity,
A work vehicle, being an articulated type in which a front frame and a rear frame are coupled, comprising; a hydraulic actuator (9a, 9b) configured to be driven by hydraulic pressure to change a vehicle body frame angle (θs_real) of the front frame with respect to the rear frame; a lever configured to be rotated to change the body frame angle (θs_real); a control valve configured to control a flow rate of oil supplied to the hydraulic actuator (9a, 9b); and a controller configured to set a target angle (θtarget) of the vehicle body frame angle (θs_real) with respect to an input angle (θi_real) of the lever and control the control valve such that an actual angle of the vehicle body frame angle (θi_real) matches the target angle (θtarget) of the vehicle body frame angle (θs_real), characterized in that an absolute value of the target value of the vehicle body frame angle (θs_real) corresponding to an absolute value of the input angle (θi_real) of the lever is larger than the absolute value of the input angle (θi_real) of the lever. a hydraulic actuator (9a, 9b) configured to be driven by hydraulic pressure to change a vehicle body frame angle (θs_real) of the front frame with respect to the rear frame; a lever configured to be rotated to change the body frame angle (θs_real); a control valve configured to control a flow rate of oil supplied to the hydraulic actuator (9a, 9b); and a controller configured to set a target angle (θtarget) of the vehicle body frame angle (θs_real) with respect to an input angle (θi_real) of the lever and control the control valve such that an actual angle of the vehicle body frame angle (θi_real) matches the target angle (θtarget) of the vehicle body frame angle (θs_real), characterized in that an absolute value of the target value of the vehicle body frame angle (θs_real) corresponding to an absolute value of the input angle (θi_real) of the lever is larger than the absolute value of the input angle (θi_real) of the lever.
An oligonucleotide which comprises two to four sequences each represented by 5'-X 1 X 2 CpGX 3 X 4 -3' and has a length of 14 to 32 nucleotides, wherein the CpG is non-methylated CpG without modified phosphate backbones, wherein the oligonucleotide comprises at least one modified phosphate backbone with a phosphorothioate which is a S-form stereoisomer at a site other than the parts represented by 5'-X 1 X 2 CpGX 3 X 4 -3', wherein the X 1 X 2 is any one of AA, AT, GA, or GT without modified phosphate backbones, and wherein the X 3 X 4 is TT, AT, AC, TC or CG without modified phosphate backbones. wherein the CpG is non-methylated CpG without modified phosphate backbones, wherein the oligonucleotide comprises at least one modified phosphate backbone with a phosphorothioate which is a S-form stereoisomer at a site other than the parts represented by 5'-X 1 X 2 CpGX 3 X 4 -3', wherein the X 1 X 2 is any one of AA, AT, GA, or GT without modified phosphate backbones, and wherein the X 3 X 4 is TT, AT, AC, TC or CG without modified phosphate backbones.
A case (1500; 1600; 1700) for protecting valuable objects which is provided to be carried by a living being comprising: - a bottom portion (1504,1604), and a lid portion (1502,1602) defining between them at least one receiving compartment (1506,1606) for receiving one or more objects to be protected, - closure means (1508, 1610) of the lid portion with the bottom portion, - attachment means (1522, 1524; 1630; 1704), referred to as external, for attachment of said case (1500; 1600; 1700) around a part of the body of a person, said case (1500; 1600; 1700) further comprising, on at least one of the outer walls of the bottom portion or of the lid portion, what is referred to as a connecting shape, provided for connecting or engaging said case (1500; 1600; 1700) in a secure manner on a base provided for that purpose, said case (1500; 1600; 1700) being characterized in that it further comprises locking means (1514-1518; 1630-1640) of the lid portion (1502; 1602) with the bottom portion (1504; 1604) in closed position, said locking means comprising an antitheft system with a lock, anti-theft nut and/or shackling. - a bottom portion (1504,1604), and a lid portion (1502,1602) defining between them at least one receiving compartment (1506,1606) for receiving one or more objects to be protected, - closure means (1508, 1610) of the lid portion with the bottom portion, - attachment means (1522, 1524; 1630; 1704), referred to as external, for attachment of said case (1500; 1600; 1700) around a part of the body of a person,
A downhole tool (103, 403, 503) comprising: a resilient body (104, 204, 304, 404, 504) configured to be disposed on a drill string into downhole tubing, the resilient body (104, 204, 304, 404, 504) comprising: a plurality of radial blades (208, 308) having an abrasive coating, wherein the radial blades (208, 308) are configured to deflect when inserted into the downhole tubing; characterized in that the resilient body (104, 204, 304, 404, 504) is configured to rotate relative to the drill string within the downhole tubing, wherein a blade angle (θ) is formed between a first blade and a second blade of the radial blades, the blade angle defined as an angle formed between a direction in which the first blade extends away from the resilient body and a direction in which the second blade extends away from the resilient body, and further wherein the first blade is deflectable toward the center of the resilient body and the blade angle formed between the first blade and the second blade is changed. a plurality of radial blades (208, 308) having an abrasive coating, wherein the radial blades (208, 308) are configured to deflect when inserted into the downhole tubing; characterized in that the resilient body (104, 204, 304, 404, 504) is configured to rotate relative to the drill string within the downhole tubing, wherein a blade angle (θ) is formed between a first blade and a second blade of the radial blades, the blade angle defined as an angle formed between a direction in which the first blade extends away from the resilient body and a direction in which the second blade extends away from the resilient body, and further wherein the first blade is deflectable toward the center of the resilient body and the blade angle formed between the first blade and the second blade is changed.
Use of a fuel composition for improving fuel economy of an internal combustion engine, the fuel composition comprising gasoline and from 10 to 750 ppm by weight based on the total weight of the fuel composition of an additive of the formula: wherein R 1 is a saturated hydrocarbyl group having from 6 to 30 carbon atoms, R 2 is a linear alkylene group, a alkoxyalkylene group, or a polyalkoxyalkylene group wherein the alkylene contains from 2 to 25 carbon atoms, R 3 is an alkylene group containing from 2 to 5 carbon atoms, R 4 is a linear alkylene group containing 2 to 3 carbon atoms, and x is an integer selected from 0 and 1.
An injection molding system, comprising: a mold clamping unit adapted to attach a mold unit to a stationary platen and a movable platen; and a mold exchange device adapted to exchange the mold unit attached to the mold clamping unit; characterized in that the injection molding system further comprises a control unit adapted to control the mold clamping unit and the mold exchange device, and a detection unit (841, 842) adapted to detect a locked state and an unlocked state of a locking mechanism (830, 835), the mold unit includes the locking mechanism (830, 835) which has the locked state where a stationary mold and a movable mold are locked and the unlocked state where locks of the stationary mold and the movable mold are released, the control unit is adapted to control the locked state and the unlocked state of the locking mechanism (830, 835), and in a case where it is detected that the locking mechanism (830, 835) of the mold unit attached to the mold clamping unit is in the unlocked state, the control unit permits mold opening by the mold clamping unit. a mold clamping unit adapted to attach a mold unit to a stationary platen and a movable platen; and a mold exchange device adapted to exchange the mold unit attached to the mold clamping unit; characterized in that the injection molding system further comprises a control unit adapted to control the mold clamping unit and the mold exchange device, and a detection unit (841, 842) adapted to detect a locked state and an unlocked state of a locking mechanism (830, 835), the mold unit includes the locking mechanism (830, 835) which has the locked state where a stationary mold and a movable mold are locked and the unlocked state where locks of the stationary mold and the movable mold are released, the control unit is adapted to control the locked state and the unlocked state of the locking mechanism (830, 835), and in a case where it is detected that the locking mechanism (830, 835) of the mold unit attached to the mold clamping unit is in the unlocked state, the control unit permits mold opening by the mold clamping unit.
A method for selecting content, comprising: displaying a single user interface handle element near a corner of a selection of content within a graphical display (710; 720), that is used to adjust a size of the selection of content; receiving an update to the size of the selection of content using the single UI handle element, wherein receiving the update to the size of the selection of content using the single UI element comprises receiving a touch based gesture that moves the single UI handle element across other content; and in response to receiving the update to the selection of content displaying a second UI handle element that may be used to adjust the size of the selection of content. displaying a single user interface handle element near a corner of a selection of content within a graphical display (710; 720), that is used to adjust a size of the selection of content; receiving an update to the size of the selection of content using the single UI handle element, wherein receiving the update to the size of the selection of content using the single UI element comprises receiving a touch based gesture that moves the single UI handle element across other content; and in response to receiving the update to the selection of content displaying a second UI handle element that may be used to adjust the size of the selection of content.