A multi-temperature control cabinet, comprising a cabinet body, a cabinet door, and a refrigerating system, wherein the refrigerating system comprises an air conditioner, a direct ventilation unit, and an environment monitoring apparatus; both the air conditioner and the direct ventilation unit are disposed on the cabinet door, and the air conditioner and the direct ventilation unit are disposed in parallel in a height direction of the cabinet door; an air guide assembly is disposed between the direct ventilation unit and an air exhaust vent of the air conditioner, wherein the air exhaust vent of the air conditioner faces an inside of the cabinet body; and the environment monitoring apparatus is connected to both the air conditioner and the direct ventilation unit, and the environment monitoring apparatus is configured to: monitor temperature and humidity in the cabinet body, and control turning-on and turning-off of the air conditioner and the direct ventilation unit based on the temperature and the humidity in the cabinet body; wherein the direct ventilation unit comprises an air intake unit and an air exhaust unit; and the air guide assembly is disposed between the air intake unit and the air exhaust vent of the air conditioner; characterized in that an air intake vent, an air mixing channel, and a mixed-air exhaust vent are disposed on the air guide assembly; the air mixing channel is connected to both the air intake vent and the mixed-air exhaust vent; the air intake vent is connected to both the air exhaust vent of the air conditioner and the air intake unit; and the mixed-air exhaust vent faces the inside of the cabinet, so that the air guide assembly is configured to mix cold air exhausted from the air exhaust vent of the air conditioner with natural air entering from the air intake unit. the refrigerating system comprises an air conditioner, a direct ventilation unit, and an environment monitoring apparatus; both the air conditioner and the direct ventilation unit are disposed on the cabinet door, and the air conditioner and the direct ventilation unit are disposed in parallel in a height direction of the cabinet door; an air guide assembly is disposed between the direct ventilation unit and an air exhaust vent of the air conditioner, wherein the air exhaust vent of the air conditioner faces an inside of the cabinet body; and the environment monitoring apparatus is connected to both the air conditioner and the direct ventilation unit, and the environment monitoring apparatus is configured to: monitor temperature and humidity in the cabinet body, and control turning-on and turning-off of the air conditioner and the direct ventilation unit based on the temperature and the humidity in the cabinet body; wherein the direct ventilation unit comprises an air intake unit and an air exhaust unit; and the air guide assembly is disposed between the air intake unit and the air exhaust vent of the air conditioner; characterized in that an air intake vent, an air mixing channel, and a mixed-air exhaust vent are disposed on the air guide assembly; the air mixing channel is connected to both the air intake vent and the mixed-air exhaust vent; the air intake vent is connected to both the air exhaust vent of the air conditioner and the air intake unit; and the mixed-air exhaust vent faces the inside of the cabinet, so that the air guide assembly is configured to mix cold air exhausted from the air exhaust vent of the air conditioner with natural air entering from the air intake unit.