A porous multi-layer filter, which is a laminated body of three porous stretched PTFE sheets that have been biaxially stretched in the longitudinal and transverse directions, comprising: a filtration layer as a middle layer; a protection layer stacked on one surface of the filtration layer on the liquid-to-be-treated inflow side; and a support layer stacked on another surface of the filtration layer, wherein: the one surface and the other surface of the filtration layer are fusion-bonded to the protection layer and the support layer at boundaries therebetween, pores of the protection layer and pores of the support layer three-dimensionally communicate with pores of the filtration layer, and the mean pore size of pores of the filtration layer is set to be smaller than the mean pore size of pores of each of the protection layer and the support layer; in the laminated body of three sheets, the difference between the tensile strength in the longitudinal direction and the tensile strength in the transverse direction is 1,500 mN or less, each of the tensile strength in the longitudinal direction and the tensile strength in the transverse direction is in the range of 2,000 to 20,000 mN, and the pressure capacity of the laminated body is 200 to 2,000 kPa; the mean pore size of the filtration layer is 0.01 to 0.45 μm, and the mean pore size of each of the protection layer and the support layer on both sides is 5 to 1,000 times the mean pore size of the filtration layer; the porosity of the filtration layer is 40% to 90%, and the porosity of each of the protection layer and the support layer is 1 to 2.5 times that of the filtration layer; a number-average molecular weight of PTFE unsintered powder forming the filtration layer is 4,000,000 to 15,000,000; and the thickness of each of the protection layer, the support layer and the filtration layer to constitute the laminated body is in the range of 5 to 60 μm, in the range 5 to 60 μm and in the range 2 to 50 μm respectively, and the total thickness of the laminated body is 10 to 150 μm, and the three sheets have the same thickness, or the protection layer and the support layer have the same thickness and the thickness of each of the protection layer and the support layer is larger than the thickness of the filtration layer. a filtration layer as a middle layer; a protection layer stacked on one surface of the filtration layer on the liquid-to-be-treated inflow side; and a support layer stacked on another surface of the filtration layer, the one surface and the other surface of the filtration layer are fusion-bonded to the protection layer and the support layer at boundaries therebetween, pores of the protection layer and pores of the support layer three-dimensionally communicate with pores of the filtration layer, and the mean pore size of pores of the filtration layer is set to be smaller than the mean pore size of pores of each of the protection layer and the support layer; in the laminated body of three sheets, the difference between the tensile strength in the longitudinal direction and the tensile strength in the transverse direction is 1,500 mN or less, each of the tensile strength in the longitudinal direction and the tensile strength in the transverse direction is in the range of 2,000 to 20,000 mN, and the pressure capacity of the laminated body is 200 to 2,000 kPa; the mean pore size of the filtration layer is 0.01 to 0.45 μm, and the mean pore size of each of the protection layer and the support layer on both sides is 5 to 1,000 times the mean pore size of the filtration layer; the porosity of the filtration layer is 40% to 90%, and the porosity of each of the protection layer and the support layer is 1 to 2.5 times that of the filtration layer; a number-average molecular weight of PTFE unsintered powder forming the filtration layer is 4,000,000 to 15,000,000; and the thickness of each of the protection layer, the support layer and the filtration layer to constitute the laminated body is in the range of 5 to 60 μm, in the range 5 to 60 μm and in the range 2 to 50 μm respectively, and the total thickness of the laminated body is 10 to 150 μm, and the three sheets have the same thickness, or the protection layer and the support layer have the same thickness and the thickness of each of the protection layer and the support layer is larger than the thickness of the filtration layer.