mhurhangee/ep-ind-claims huggingface dataset:
A compound of Formula: or a pharmaceutically acceptable salt thereof, wherein: R 1 is hydrogen, C 1 alkyl, C 1-6 haloalkyl, C 3-8 carbocyclyl, phenyl, O-phenyl, wherein C 1 alkyl, C 1-6 haloalkyl, C 3-8 carbocyclyl, phenyl, or O-phenyl is optionally substituted by one or more halo, 3-8 membered heterocyclyl, or -OR c; R 2 is independently hydrogen, C 1-6 alkyl, or halo; R 3 is -OR 7, C 1-6 alkyl, halo, cyano, nitro, C 3-8 carbocyclyl, 3-8 membered heterocyclyl, -N(R d) 2, -C R c, -C OR c, or -C N(R d) 2, wherein C 1-6 alkyl, C 3-8 carbocyclyl, or 3-8 membered heterocyclyl is optionally substituted with one or more R 5; R 4 is halo, C 1-6 alkyl, cyano, nitro, C 3-8 carbocyclyl, 3-8 membered heterocyclyl, -OR c, -N(R d) 2, -C R c, -C OR c, or -C N(R d) 2, wherein C 1-6 alkyl, C 3-8 carbocyclyl, or 3-8 membered heterocyclyl are optionally substituted with one or more R 5; m is 1, 0, or 2; each R 5 is independently halo, cyano, nitro, C 1-6 alkyl, C 3-8 carbocyclyl, 3-8 membered heterocyclyl, -OR c, -C N(R d) 2, -SO 2 R c, -SO 2 OR c, -SO 2 N(R d) 2, -NR d C (R c), or - N(R d) 2; each R c is independently hydrogen or C 1-6 alkyl, wherein each C 1-6 alkyl is optionally substituted with one or more R 6; each R d is independently hydrogen or C 1-6 alkyl; each R 6 is independently halogen, cyano, C 3-8 carbocyclyl, or 3-8 membered heterocyclyl; wherein the C 3-8 carbocyclyl is optionally substituted with one or more halogens or cyano; and R 7 is C 1-6 alkyl or C 3-8 carbocyclyl wherein C 1-6 alkyl or C 3-8 carbocyclyl is optionally substituted with one or more R 6. R 1 is hydrogen, C 1 alkyl, C 1-6 haloalkyl, C 3-8 carbocyclyl, phenyl, O-phenyl, wherein C 1 alkyl, C 1-6 haloalkyl, C 3-8 carbocyclyl, phenyl, or O-phenyl is optionally substituted by one or more halo, 3-8 membered heterocyclyl, or -OR c; R 2 is independently hydrogen, C 1-6 alkyl, or halo; R 3 is -OR 7, C 1-6 alkyl, halo, cyano, nitro, C 3-8 carbocyclyl, 3-8 membered heterocyclyl, -N(R d) 2, -C R c, -C OR c, or -C N(R d) 2, wherein C 1-6 alkyl, C 3-8 carbocyclyl, or 3-8 membered heterocyclyl is optionally substituted with one or more R 5; R 4 is halo, C 1-6 alkyl, cyano, nitro, C 3-8 carbocyclyl, 3-8 membered heterocyclyl, -OR c, -N(R d) 2, -C R c, -C OR c, or -C N(R d) 2, wherein C 1-6 alkyl, C 3-8 carbocyclyl, or 3-8 membered heterocyclyl are optionally substituted with one or more R 5; m is 1, 0, or 2; each R 5 is independently halo, cyano, nitro, C 1-6 alkyl, C 3-8 carbocyclyl, 3-8 membered heterocyclyl, -OR c, -C N(R d) 2, -SO 2 R c, -SO 2 OR c, -SO 2 N(R d) 2, -NR d C (R c), or - N(R d) 2; each R c is independently hydrogen or C 1-6 alkyl, wherein each C 1-6 alkyl is optionally substituted with one or more R 6; each R d is independently hydrogen or C 1-6 alkyl; each R 6 is independently halogen, cyano, C 3-8 carbocyclyl, or 3-8 membered heterocyclyl; wherein the C 3-8 carbocyclyl is optionally substituted with one or more halogens or cyano; and R 7 is C 1-6 alkyl or C 3-8 carbocyclyl wherein C 1-6 alkyl or C 3-8 carbocyclyl is optionally substituted with one or more R 6.
A cigarette flavour applicator, comprising a housing defining a reservoir for the flavour; an application tip arranged in use in contact with the reservoir; a flavouring contained within the reservoir for application to the filter of a cigarette; and, a closure mechanism arranged in use to provide a seal to the reservoir and characterised in that the closure mechanism is arranged such that upon application of pressure to the application tip release of flavouring from the reservoir is enabled, in which the application tip comprises a fibrous or a porous ceramic material arranged to wick flavour from the reservoir. a housing defining a reservoir for the flavour; an application tip arranged in use in contact with the reservoir; a flavouring contained within the reservoir for application to the filter of a cigarette; and, a closure mechanism arranged in use to provide a seal to the reservoir and characterised in that the closure mechanism is arranged such that upon application of pressure to the application tip release of flavouring from the reservoir is enabled, in which the application tip comprises a fibrous or a porous ceramic material arranged to wick flavour from the reservoir.
A composition obtained from cooking or blanching water of peas, preferably green peas, comprising -(β-D-glucopyranosyloxy)-1,5-dihydro-2 H -pyrrol-2-one in an amount of at least 0.4% (by total dry weight of the composition) for umami taste and/or flavor enhancing of a food product.
A method for generating a request injection file for an IT infrastructure test, said IT infrastructure test including an execution of the requests from the injection file in order to measure the performance of the IT infrastructure based on the results of execution of these requests, the method for generating a request injection file including the following steps of: - reading a test configuration file, by a processing unit, including at least one definition of at least one test scenario, said configuration file including at least one test parameter for each scenario, the at least one test parameter corresponding to a duration-request variable allowing to calculate a variable waiting duration after a request by subtracting an actual duration of the request from the value of the duration-request variable; - initializing the request injection file from a base file including markers, and having a format adapted to an injection device with fields to fill in; - calculating at least one test variable for each test scenario of the configuration file, from the at least one test parameter for each scenario, said test variable allowing the injection device to clock the requests sent to the IT infrastructure; - a step of substituting at least one marker of the base file initializing the request injection file with the calculated test variable, and - generating, when all the test scenarios have been considered, the request injection file, by a scheduling module, said request injection file including a plurality of requests to the IT infrastructure from at least said at least one calculated test variable. - reading a test configuration file, by a processing unit, including at least one definition of at least one test scenario, said configuration file including at least one test parameter for each scenario, the at least one test parameter corresponding to a duration-request variable allowing to calculate a variable waiting duration after a request by subtracting an actual duration of the request from the value of the duration-request variable; - initializing the request injection file from a base file including markers, and having a format adapted to an injection device with fields to fill in; - calculating at least one test variable for each test scenario of the configuration file, from the at least one test parameter for each scenario, said test variable allowing the injection device to clock the requests sent to the IT infrastructure; - a step of substituting at least one marker of the base file initializing the request injection file with the calculated test variable, and - generating, when all the test scenarios have been considered, the request injection file, by a scheduling module, said request injection file including a plurality of requests to the IT infrastructure from at least said at least one calculated test variable.
A navigation system comprising: a tool configured to be advanced through a patient's luminal network, the tool having a first electromagnetic position sensor located on the distal end of the tool; a catheter configured to receive the tool, the catheter having a second electromagnetic position sensor located on the distal end of the catheter; an electromagnetic tracking system (142, 132) for tracking the positions of the first and second sensors; a display device; a processor and associated memory, the processor coupled to the display device and to the tracking system, the memory storing instructions (206, 208, 210) that when executed by the processor cause the processor to: display an image of a portion of a patient's luminal network on the display device; identify a location of a target site within a patient's body; track a location of the tool having the first sensor; determine a distance between the location of a target site and the tool; display, on the display, the determined distance between the location of a target site and the tool; track a location of the catheter having the second sensor; determine (S406a) a distance between the location of the tool and the catheter; and display, on the display, the distance between the location of the tool and the catheter. a tool configured to be advanced through a patient's luminal network, the tool having a first electromagnetic position sensor located on the distal end of the tool; a catheter configured to receive the tool, the catheter having a second electromagnetic position sensor located on the distal end of the catheter; an electromagnetic tracking system (142, 132) for tracking the positions of the first and second sensors; a display device; a processor and associated memory, the processor coupled to the display device and to the tracking system, the memory storing instructions (206, 208, 210) that when executed by the processor cause the processor to: display an image of a portion of a patient's luminal network on the display device; identify a location of a target site within a patient's body; track a location of the tool having the first sensor; determine a distance between the location of a target site and the tool; display, on the display, the determined distance between the location of a target site and the tool; track a location of the catheter having the second sensor; determine (S406a) a distance between the location of the tool and the catheter; and display, on the display, the distance between the location of the tool and the catheter. display an image of a portion of a patient's luminal network on the display device; identify a location of a target site within a patient's body; track a location of the tool having the first sensor; determine a distance between the location of a target site and the tool; display, on the display, the determined distance between the location of a target site and the tool; track a location of the catheter having the second sensor; determine (S406a) a distance between the location of the tool and the catheter; and display, on the display, the distance between the location of the tool and the catheter.
A method for uplink transmission without dynamic grant, comprising: receiving (204, 254), by a user equipment, UE, a radio resource control, RRC, signaling carrying one or more configurations for one or more bandwidth parts within a system bandwidth and one or more configuration of resources for transmission without dynamic grant including demodulation reference signal, DMRS, configuration, associated with the one or more bandwidth parts, the configuration for each of the one or more bandwidth parts comprising a numerology, a starting frequency domain location, a frequency domain length for transmission without dynamic grant; and performing (207, 256), by the UE, uplink transmission without dynamic grant according to the resources configuration in a bandwidth part of the one or more bandwidth parts. receiving (204, 254), by a user equipment, UE, a radio resource control, RRC, signaling carrying one or more configurations for one or more bandwidth parts within a system bandwidth and one or more configuration of resources for transmission without dynamic grant including demodulation reference signal, DMRS, configuration, associated with the one or more bandwidth parts, the configuration for each of the one or more bandwidth parts comprising a numerology, a starting frequency domain location, a frequency domain length for transmission without dynamic grant; and performing (207, 256), by the UE, uplink transmission without dynamic grant according to the resources configuration in a bandwidth part of the one or more bandwidth parts.
A propeller for an aircraft, said propeller comprising: a core internal structure; and a structural skin laminate deposed outside said core, said structural skin laminate encapsulating a hub portion along with at least one blade portion (14, 16) and being continuous at least where said blade (14, 16) and hub interface; characterized in that said skin laminate includes a fibrous braid sleeve encapsulating said core internal structure and is one of a resin-transfer-molding product and a cured epoxy material or both. a core internal structure; and a structural skin laminate deposed outside said core, said structural skin laminate encapsulating a hub portion along with at least one blade portion (14, 16) and being continuous at least where said blade (14, 16) and hub interface; characterized in that said skin laminate includes a fibrous braid sleeve encapsulating said core internal structure and is one of a resin-transfer-molding product and a cured epoxy material or both.
Heat exchanger for gas condensing boilers, provided with a suitable container body, at least one pipe bundle, at least one temperature sensor means, where said pipe bundle is made by a pipe spiral wound around a central axis, adapted to form a suitable number of turns delimiting a combustion chamber, and provides a first end which serves as an inlet for the heat transfer fluid to be heated, and a second end which serves as an outlet for said heat transfer fluid, wherein said first and second ends (31; 32) protrude from said container body, wherein said exchanger is provided with a partition adapted to divide the combustion chamber into a first sensitive chamber and into a second condensing chamber, wherein - said partition comprises a disc-shaped element having an outer profile with helical pattern, provided with a layer of insulating material, - said partition is screwable along the turns of the pipe bundle, so as to regulate and vary the dimensions of the said chambers (310; 320), and characterised in that - said at least one temperature sensor means is constrained and fixed to said first and second ends (31; 32) through appropriate mounting means; - said mounting means comprise the fixing means that carry out the locking of the said ends (31; 32) with the pipes. wherein said exchanger is provided with a partition adapted to divide the combustion chamber into a first sensitive chamber and into a second condensing chamber, wherein - said partition comprises a disc-shaped element having an outer profile with helical pattern, provided with a layer of insulating material, - said partition is screwable along the turns of the pipe bundle, so as to regulate and vary the dimensions of the said chambers (310; 320), and characterised in that - said at least one temperature sensor means is constrained and fixed to said first and second ends (31; 32) through appropriate mounting means; - said mounting means comprise the fixing means that carry out the locking of the said ends (31; 32) with the pipes. - said partition comprises a disc-shaped element having an outer profile with helical pattern, provided with a layer of insulating material, - said partition is screwable along the turns of the pipe bundle, so as to regulate and vary the dimensions of the said chambers (310; 320), and characterised in that - said at least one temperature sensor means is constrained and fixed to said first and second ends (31; 32) through appropriate mounting means; - said mounting means comprise the fixing means that carry out the locking of the said ends (31; 32) with the pipes.
A vacuum pump suitable for mounting at a lower region of an engine such as in the oil sump of the engine, the vacuum pump including a casing having a cavity containing a rotor and a vane slidably mounted in a slot of the rotor, wherein the cavity is provided with an inlet and an outlet and the rotor and vane (16,18) movable to draw fluid into the cavity through the inlet and out of the cavity through the outlet so as to induce a reduction in pressure at the inlet, wherein further the vacuum pump is provided with an oil feed conduit to supply oil to the cavity, the oil feed conduit being provided with a valve to prevent the flow of oil to the cavity during periods when the pump is not operating, the inlet to the pump cavity being provided with a valve which is arranged to close when the pump is not operating, characterised in that the oil feed conduit valve is provided within the pump casing and the oil feed conduit extends through the casing from the exterior thereof to the cavity via an oil gallery of the pump defined between the rotor and the casing wherein further the pump outlet is provided with a reed valve and a stop.
A safety switching device having a reset input for starting the safety switching device after the safety function thereof has been triggered, an evaluation circuit being connected to the reset input to detect the application of a start signal, and the safety switching device providing different start modes and being designed to select a start mode in agreement with the detected start signal, characterized in that the evaluation circuit comprises a sampling device so as to sample the signal that is present at the reset input and detect the same from a sequence of sampled values.
A method for forming a buried metal line in a substrate, the method comprising: at a position between a pair of semiconductor structures protruding from the substrate, forming a metal line trench in the substrate at a level below a base of each semiconductor structure of the pair, wherein forming the metal line trench comprises: etching an upper trench portion in the substrate, forming a spacer on sidewall surfaces of of the upper trench portion, the spacer exposing a bottom surface of the upper trench portion, and while the spacer masks the sidewall surfaces of the upper trench portion, etching a lower trench portion, comprising etching the substrate via the upper trench portion such that a width of the lower trench portion exceeds a width of the upper trench portion, and forming the metal line in the metal line trench, wherein the buried metal line forms a buried power rail. at a position between a pair of semiconductor structures protruding from the substrate, forming a metal line trench in the substrate at a level below a base of each semiconductor structure of the pair, wherein forming the metal line trench comprises: etching an upper trench portion in the substrate, forming a spacer on sidewall surfaces of of the upper trench portion, the spacer exposing a bottom surface of the upper trench portion, and while the spacer masks the sidewall surfaces of the upper trench portion, etching a lower trench portion, comprising etching the substrate via the upper trench portion such that a width of the lower trench portion exceeds a width of the upper trench portion, and etching an upper trench portion in the substrate, forming a spacer on sidewall surfaces of of the upper trench portion, the spacer exposing a bottom surface of the upper trench portion, and while the spacer masks the sidewall surfaces of the upper trench portion, etching a lower trench portion, comprising etching the substrate via the upper trench portion such that a width of the lower trench portion exceeds a width of the upper trench portion, and forming the metal line in the metal line trench, wherein the buried metal line forms a buried power rail.
A peptidomimetic polymer comprising a coupled polypeptide moiety and a polypeptoid moiety, the polypeptide moiety consisting of a 5-mer peptide mimic of Mefp-5 comprising alternating residues of L-3, 4-dihydroxyphenylalanine (DOPA) and lysine, wherein the polypeptoid moiety comprises a poly-N-substituted glycine oligomer, wherein the N- substituent is methoxy ethyl.
Vehicle with a seat belt arrangement, wherein the seat belt arrangement has a seat belt which has a shoulder belt portion and a lap belt portion which, at its outer coupling point in the transverse direction (y) of the vehicle, has a belt deflector via which the lap belt portion is guided to a belt-tensioner device in the region of a door sill, wherein the door sill has a retaining profile part which bears an entry strip bounding the door entry region, characterized in that a construction space in which the belt-tensioner device is arranged is formed between the retaining profile part and a vehicle floor assembly located below the latter, and in that the retaining profile part bounds the construction space for the belt-tensioner device with a vertical boundary wall spaced apart with a transverse offset (Δy) from the door sill and with a horizontal boundary wall spaced apart with a height offset (Δz) from the floor assembly.
An implantable device (100, 301, 303, 304, 305, 500, 550, 600, 800, 850, 900) for the replacement or repair of articular cartilage tissue, comprising: a first fabric (101, 501, 601, 801, 921) adapted for articulation against a tissue within a human or animal body, a second fabric (103, 503, 603, 803) adapted for tissue ingrowth within a human or animal body, a plurality of spacer elements (102, 502, 602, 802) connecting the first fabric to the second fabric, wherein the plurality of spacer elements separates the first fabric from the second fabric, wherein the first fabric and the second fabric define an interfabric space, and at least one fabric fixation point provided by the first fabric, the second fabric, or both, wherein the plurality of spacer elements provides compressive stiffness along an axis normal to a point on the first fabric, wherein the plurality of spacer elements provides compressive strength along an axis normal to a point on the first fabric, wherein the implantable device is adapted to replace or repair damaged or diseased cartilage tissue in a human or animal body in need thereof, characterised in that the implantable device has a thickness in an uncompressed state, and exhibits a return to at least 95 % of that thickness within one minute upon removal of a compressive force ranging from about 1 to about 12 MPa. a first fabric (101, 501, 601, 801, 921) adapted for articulation against a tissue within a human or animal body, a second fabric (103, 503, 603, 803) adapted for tissue ingrowth within a human or animal body, a plurality of spacer elements (102, 502, 602, 802) connecting the first fabric to the second fabric, wherein the plurality of spacer elements separates the first fabric from the second fabric, wherein the first fabric and the second fabric define an interfabric space, and at least one fabric fixation point provided by the first fabric, the second fabric, or both, wherein the plurality of spacer elements provides compressive stiffness along an axis normal to a point on the first fabric, wherein the plurality of spacer elements provides compressive strength along an axis normal to a point on the first fabric, wherein the implantable device is adapted to replace or repair damaged or diseased cartilage tissue in a human or animal body in need thereof, characterised in that the implantable device has a thickness in an uncompressed state, and exhibits a return to at least 95 % of that thickness within one minute upon removal of a compressive force ranging from about 1 to about 12 MPa. wherein the plurality of spacer elements provides compressive stiffness along an axis normal to a point on the first fabric, wherein the plurality of spacer elements provides compressive strength along an axis normal to a point on the first fabric, wherein the implantable device is adapted to replace or repair damaged or diseased cartilage tissue in a human or animal body in need thereof, characterised in that the implantable device has a thickness in an uncompressed state, and exhibits a return to at least 95 % of that thickness within one minute upon removal of a compressive force ranging from about 1 to about 12 MPa.