An unoccluded topical oxybutynin gel formulation comprising: a. a therapeutically effective amount of oxybutynin; b. 0.05 wt.% to 10 wt.% of a gel carrier selected from: i. polyacrylic acids or poly(1-carboxythylene), carboxypolymethylenes prepared from acrylic acid cross-linked with allyl ethers of (polyalkyl) sucrose or pentaerythritol, carbamer polymers, sodium acrylate polymers, other polycarboxylic acids, alkyl acrylate polymers and mixtures or copolymers thereof, ii. carboxyvinyl polymers, polyvinyl pyrrolidone, polyvinyl alcohol, polyvinyl methyl ether, poly-vinyl ether, polyvinyl sulfonates, and mixtures or copolymers thereof, iii. polyethylene compounds, polysaccharides and salts thereof, acrylic acid esters, alkoxybutyninpolymers, polyoxyethylene-polyoxypropylene copolymers, polyethylene oxide polymers, polyethers, gelatin succinate, colloidal magnesium aluminum silicate, petroleum jelly and mixtures or copolymers thereof, iv. hydroxypropyl cellulose, hydroxypropylmethyl cellulose, hydroxypropylethyl cellulose, hydroxypropylbutyl cellulose, hydroxypropylpentyl cellulose, hydroxyethyl cellulose, ethylcellulose, carboxymethyl cellulose, hydroxypropylmethyl cellulose phthalate and cellulose acetate, or v. dextran, guar-gum, tragacanth, xanthan gum, sodium alginate, sodium pectinate, sodium laginate, acacia gum, Irish moss, karaya gum, guaiac gum, locust bean gum, casein, gelatin, collagen, albumin, globulin, fibrin, cellulose, dextrin, pectin, starches, agar and mannan; c. 60 wt.% to 85 wt.% of ethanol or at least 70 wt.% of a solvent selected from ethanol, isopropanol, propanol, methanol, and mixtures thereof; and d. 1 wt.% to 30 wt.% water, wherein: a. the formulation has a pH of from 4 to 11; and b. the oxybutynin is present as an oxybutynin free base, a pharmaceutically acceptable oxybutynin salt, or a mixture thereof. a. a therapeutically effective amount of oxybutynin; b. 0.05 wt.% to 10 wt.% of a gel carrier selected from: i. polyacrylic acids or poly(1-carboxythylene), carboxypolymethylenes prepared from acrylic acid cross-linked with allyl ethers of (polyalkyl) sucrose or pentaerythritol, carbamer polymers, sodium acrylate polymers, other polycarboxylic acids, alkyl acrylate polymers and mixtures or copolymers thereof, ii. carboxyvinyl polymers, polyvinyl pyrrolidone, polyvinyl alcohol, polyvinyl methyl ether, poly-vinyl ether, polyvinyl sulfonates, and mixtures or copolymers thereof, iii. polyethylene compounds, polysaccharides and salts thereof, acrylic acid esters, alkoxybutyninpolymers, polyoxyethylene-polyoxypropylene copolymers, polyethylene oxide polymers, polyethers, gelatin succinate, colloidal magnesium aluminum silicate, petroleum jelly and mixtures or copolymers thereof, iv. hydroxypropyl cellulose, hydroxypropylmethyl cellulose, hydroxypropylethyl cellulose, hydroxypropylbutyl cellulose, hydroxypropylpentyl cellulose, hydroxyethyl cellulose, ethylcellulose, carboxymethyl cellulose, hydroxypropylmethyl cellulose phthalate and cellulose acetate, or v. dextran, guar-gum, tragacanth, xanthan gum, sodium alginate, sodium pectinate, sodium laginate, acacia gum, Irish moss, karaya gum, guaiac gum, locust bean gum, casein, gelatin, collagen, albumin, globulin, fibrin, cellulose, dextrin, pectin, starches, agar and mannan; i. polyacrylic acids or poly(1-carboxythylene), carboxypolymethylenes prepared from acrylic acid cross-linked with allyl ethers of (polyalkyl) sucrose or pentaerythritol, carbamer polymers, sodium acrylate polymers, other polycarboxylic acids, alkyl acrylate polymers and mixtures or copolymers thereof, ii. carboxyvinyl polymers, polyvinyl pyrrolidone, polyvinyl alcohol, polyvinyl methyl ether, poly-vinyl ether, polyvinyl sulfonates, and mixtures or copolymers thereof, iii. polyethylene compounds, polysaccharides and salts thereof, acrylic acid esters, alkoxybutyninpolymers, polyoxyethylene-polyoxypropylene copolymers, polyethylene oxide polymers, polyethers, gelatin succinate, colloidal magnesium aluminum silicate, petroleum jelly and mixtures or copolymers thereof, iv. hydroxypropyl cellulose, hydroxypropylmethyl cellulose, hydroxypropylethyl cellulose, hydroxypropylbutyl cellulose, hydroxypropylpentyl cellulose, hydroxyethyl cellulose, ethylcellulose, carboxymethyl cellulose, hydroxypropylmethyl cellulose phthalate and cellulose acetate, or v. dextran, guar-gum, tragacanth, xanthan gum, sodium alginate, sodium pectinate, sodium laginate, acacia gum, Irish moss, karaya gum, guaiac gum, locust bean gum, casein, gelatin, collagen, albumin, globulin, fibrin, cellulose, dextrin, pectin, starches, agar and mannan; c. 60 wt.% to 85 wt.% of ethanol or at least 70 wt.% of a solvent selected from ethanol, isopropanol, propanol, methanol, and mixtures thereof; and d. 1 wt.% to 30 wt.% water, a. the formulation has a pH of from 4 to 11; and b. the oxybutynin is present as an oxybutynin free base, a pharmaceutically acceptable oxybutynin salt, or a mixture thereof.