A composition for disrupting biofilms, comprising: i. from 0.005% to 10% of a biofilm disruptor comprising at least one unsaturated aliphatic long chain alcohol or aldehyde of the formula: R 1 (C n R 2 s H (2n-2m-s))R 3 (C x R 4 t H (2x-2y-t))R 5 CH 2 R 6 wherein R 1 and R 6 are, independently, H-, HO-, O=CH-, CH 3 - or CH 2 =CH-, (-OCH 2 -) z R 7, -OCH 2 CH 2 -) z R 7, (-OCH 2 CH(CH 3)-) z R 7; R 2 and R 4 are, independent of themselves and independent of each other, HO-, O=CH-, branched or straight chain C 1 to C 4 alkyl or alkene, -CH 2 OH, -CH 2 CH 2 OH; R 3 is, independently, single bond or -O-; R 5 is, independently, single bond, -O-, (-OCH 2 -) z, (-OCH 2 CH 2 -) z, (-OCH 2 CH(CH 3)-) z; R 7 is, independent of itself, H-, HO-, O=CH-, CH 3 - or CH 2 =CH-; n is an integer from 1 to 10; m is an integer from 0 to n/2 if n is even or (n-1)/2 if n is odd; x is an integer from 0 to 10; y is an integer from 0 to x/2 if x is even or (x-1)/2 if x is odd and z is an integer from 0 to 5; s is an integer ≤ n; and t is an integer ≤ x, provided that: if neither R 1, R 2, R 4, nor R 6 contain any C=C unsaturation, then m+y is at least 1; R 5 and R 6 are not such that R 5 is (-OCH 2 -) z, (-OCH 2 CH 2 -) z, (-OCH 2 CH(CH 3)-) z, and R 6 is (-OCH 2 -) z R 7, (-OCH 2 CH 2 -) z R 7, (-OCH 2 CH(CH 3)-) z R 7; the carbon-carbon chain length from R 1 to R 6 ranges continuously or intermittently from 8 to 13 carbons; and at least one of any one of R 1, R 2, R 4 and R 6 contains HO- or O=CH-; ii. optionally, a therapeutic active; and iii. a carrier selected from the group consisting of a non-oral carrier, pharmaceutically acceptable carrier, orally acceptable carrier and dermatogically acceptable carrier. i. from 0.005% to 10% of a biofilm disruptor comprising at least one unsaturated aliphatic long chain alcohol or aldehyde of the formula: R 1 (C n R 2 s H (2n-2m-s))R 3 (C x R 4 t H (2x-2y-t))R 5 CH 2 R 6 wherein R 1 and R 6 are, independently, H-, HO-, O=CH-, CH 3 - or CH 2 =CH-, (-OCH 2 -) z R 7, -OCH 2 CH 2 -) z R 7, (-OCH 2 CH(CH 3)-) z R 7; R 2 and R 4 are, independent of themselves and independent of each other, HO-, O=CH-, branched or straight chain C 1 to C 4 alkyl or alkene, -CH 2 OH, -CH 2 CH 2 OH; R 3 is, independently, single bond or -O-; R 5 is, independently, single bond, -O-, (-OCH 2 -) z, (-OCH 2 CH 2 -) z, (-OCH 2 CH(CH 3)-) z; R 7 is, independent of itself, H-, HO-, O=CH-, CH 3 - or CH 2 =CH-; n is an integer from 1 to 10; m is an integer from 0 to n/2 if n is even or (n-1)/2 if n is odd; x is an integer from 0 to 10; y is an integer from 0 to x/2 if x is even or (x-1)/2 if x is odd and z is an integer from 0 to 5; s is an integer ≤ n; and t is an integer ≤ x, provided that: if neither R 1, R 2, R 4, nor R 6 contain any C=C unsaturation, then m+y is at least 1; R 5 and R 6 are not such that R 5 is (-OCH 2 -) z, (-OCH 2 CH 2 -) z, (-OCH 2 CH(CH 3)-) z, and R 6 is (-OCH 2 -) z R 7, (-OCH 2 CH 2 -) z R 7, (-OCH 2 CH(CH 3)-) z R 7; the carbon-carbon chain length from R 1 to R 6 ranges continuously or intermittently from 8 to 13 carbons; and at least one of any one of R 1, R 2, R 4 and R 6 contains HO- or O=CH-; if neither R 1, R 2, R 4, nor R 6 contain any C=C unsaturation, then m+y is at least 1; R 5 and R 6 are not such that R 5 is (-OCH 2 -) z, (-OCH 2 CH 2 -) z, (-OCH 2 CH(CH 3)-) z, and R 6 is (-OCH 2 -) z R 7, (-OCH 2 CH 2 -) z R 7, (-OCH 2 CH(CH 3)-) z R 7; the carbon-carbon chain length from R 1 to R 6 ranges continuously or intermittently from 8 to 13 carbons; and at least one of any one of R 1, R 2, R 4 and R 6 contains HO- or O=CH-; ii. optionally, a therapeutic active; and iii. a carrier selected from the group consisting of a non-oral carrier, pharmaceutically acceptable carrier, orally acceptable carrier and dermatogically acceptable carrier.