A preamble sequence sending method, comprising: Generating, by a transmit end, a frequency offset estimation sequence, wherein the frequency offset estimation sequence comprises N subsequences each with a length of M, N is a positive integer greater than or equal to 2, and M is a positive integer; Generating, by the transmit end, a prefix and a suffix based on the frequency offset estimation sequence, comprising the steps of: replicating, by the transmit end, last L1 element values comprised in the first subsequence of the frequency offset estimation sequence, and separately rotating the replicated L1 element values by a phase of - θ to generate the prefix; and replicating, by the transmit end, first L2 element values comprised in the last subsequence of the frequency offset estimation sequence, and separately rotating the replicated L2 element values by a phase of θ to generate the suffix; wherein L1 and L2 are set by the transmit end according to a channel multipath feature, and L1 and L2 are integers not greater than M; Adding, by the transmit end, the prefix and the suffix before and after the frequency offset estimation sequence respectively to form a preamble sequence, wherein the prefix and the suffix are used for canceling multipath interference, wherein each subsequence comprised in the frequency offset estimation sequence is rotated by a phase of θ relative to a previous subsequence adjacent to the subsequence, and - π ≤ θ ≤ π and θ ≠ 0; and Adding, by the transmit end, the preamble sequence to a data packet and sending the data packet to a receive end. Generating, by a transmit end, a frequency offset estimation sequence, wherein the frequency offset estimation sequence comprises N subsequences each with a length of M, N is a positive integer greater than or equal to 2, and M is a positive integer; Generating, by the transmit end, a prefix and a suffix based on the frequency offset estimation sequence, comprising the steps of: replicating, by the transmit end, last L1 element values comprised in the first subsequence of the frequency offset estimation sequence, and separately rotating the replicated L1 element values by a phase of - θ to generate the prefix; and replicating, by the transmit end, first L2 element values comprised in the last subsequence of the frequency offset estimation sequence, and separately rotating the replicated L2 element values by a phase of θ to generate the suffix; wherein L1 and L2 are set by the transmit end according to a channel multipath feature, and L1 and L2 are integers not greater than M; replicating, by the transmit end, last L1 element values comprised in the first subsequence of the frequency offset estimation sequence, and separately rotating the replicated L1 element values by a phase of - θ to generate the prefix; and replicating, by the transmit end, first L2 element values comprised in the last subsequence of the frequency offset estimation sequence, and separately rotating the replicated L2 element values by a phase of θ to generate the suffix; wherein L1 and L2 are set by the transmit end according to a channel multipath feature, and L1 and L2 are integers not greater than M; Adding, by the transmit end, the prefix and the suffix before and after the frequency offset estimation sequence respectively to form a preamble sequence, wherein the prefix and the suffix are used for canceling multipath interference, wherein each subsequence comprised in the frequency offset estimation sequence is rotated by a phase of θ relative to a previous subsequence adjacent to the subsequence, and - π ≤ θ ≤ π and θ ≠ 0; and Adding, by the transmit end, the preamble sequence to a data packet and sending the data packet to a receive end.