mhurhangee/ep-ind-claims huggingface dataset:
A compound of formula: or a tautomer, stereoisomer, pharmaceutically acceptable salt, or solvate thereof, wherein: ring B is optionally substituted furanyl; ring C is aryl or heteroaryl; ring D is pyridinyl; each of X, Y, and Z is independently selected from the group consisting of O, CH 2, NR x and S q, wherein R x is hydrogen or alkyl; R 1 is hydrogen or alkyl; each R 2 is independently selected from the group consisting of hydrogen, alkyl, halo, hydroxyl, haloalkyl, alkoxy, alkylthio, amino, amide, alkylamine, aminoalkyl, cyano, hydroxyalkyl, -(CH 2) p C OR 6, and -(CH 2) p OC R 6; each R 3 is independently selected from the group consisting of hydrogen, alkyl and halo; R 4 is hydrogen or alkyl; R 5 is hydrogen; each R 6 is independently selected from the group consisting of hydrogen and alkyl, wherein the alkyl is unsubstituted or substituted with one or more groups independently selected from the group consisting of amino, hydroxyl, halo, and alkoxy; m is 1, 2, 3, or 4; n is 1, 2, 3, 4, or 5; p is 0, 1, 2, 3, 4, or 5; and q is 0, 1, or 2. ring B is optionally substituted furanyl; ring C is aryl or heteroaryl; ring D is pyridinyl; each of X, Y, and Z is independently selected from the group consisting of O, CH 2, NR x and S q, wherein R x is hydrogen or alkyl; R 1 is hydrogen or alkyl; each R 2 is independently selected from the group consisting of hydrogen, alkyl, halo, hydroxyl, haloalkyl, alkoxy, alkylthio, amino, amide, alkylamine, aminoalkyl, cyano, hydroxyalkyl, -(CH 2) p C OR 6, and -(CH 2) p OC R 6; each R 3 is independently selected from the group consisting of hydrogen, alkyl and halo; R 4 is hydrogen or alkyl; R 5 is hydrogen; each R 6 is independently selected from the group consisting of hydrogen and alkyl, wherein the alkyl is unsubstituted or substituted with one or more groups independently selected from the group consisting of amino, hydroxyl, halo, and alkoxy; m is 1, 2, 3, or 4; n is 1, 2, 3, 4, or 5; p is 0, 1, 2, 3, 4, or 5; and q is 0, 1, or 2.
A pharmaceutical dosage form (1; 51) for the application to a mucous membrane, in particular to a buccal, gastro-intestinal, rectal or vaginal mucous membrane, preferably a gastro-intestinal membrane, more preferably an esophageal membrane comprising at least one preparation (2; 52) having an elongated shape and comprising an active pharmaceutical ingredient, the at least one preparation being capable to be arranged in a compact condition and in an expanded condition, a capsule device (3; 53) comprising a hollow space (4; 54a, 54b) for accommodating the at least one preparation being in the compact condition, the capsule device having an opening (5; 25; 35; 45.1; 45.2; 45.3; 55) and a first end (2a; 52a) of the preparation extending, in the compact condition, through the opening (5; 25; 35; 45.1; 45.2; 45.3; 55) for allowing pulling out the preparation from the hollow space into the surrounding area of the capsule device thereby transferring the preparation from the compact condition to the expanded condition, characterized in that the opening (5; 55) and the preparation (2; 52) being dimensioned such that, when the preparation is pulled out from the opening (5; 25; 35; 45.1; 45.2; 45.3; 55), a spacing (S1; S2) is provided in an opening cross section of the opening (5; 55) between the preparation (2; 52) and a surface of the capsule device defining the opening (5; 55). at least one preparation (2; 52) having an elongated shape and comprising an active pharmaceutical ingredient, the at least one preparation being capable to be arranged in a compact condition and in an expanded condition, a capsule device (3; 53) comprising a hollow space (4; 54a, 54b) for accommodating the at least one preparation being in the compact condition, the capsule device having an opening (5; 25; 35; 45.1; 45.2; 45.3; 55) and a first end (2a; 52a) of the preparation extending, in the compact condition, through the opening (5; 25; 35; 45.1; 45.2; 45.3; 55) for allowing pulling out the preparation from the hollow space into the surrounding area of the capsule device thereby transferring the preparation from the compact condition to the expanded condition, characterized in that the opening (5; 55) and the preparation (2; 52) being dimensioned such that, when the preparation is pulled out from the opening (5; 25; 35; 45.1; 45.2; 45.3; 55), a spacing (S1; S2) is provided in an opening cross section of the opening (5; 55) between the preparation (2; 52) and a surface of the capsule device defining the opening (5; 55).
A textile cleaning composition comprising: at least 0.2wt% of a stain treatment additive, wherein the stain treatment additive comprises an ester of glycerol and a C 16 to C 20 fatty acid, wherein the glycerol has been ethoxylated with from 6 to 10 mols of ethylene oxide, wherein the fatty acid comprises at least 50wt% isostearic acid, based on the total weight of fatty acid present, and wherein the ester comprises at least 20wt% mono-ester; and at least 10wt% in total of one or more surfactants or mixtures thereof, not including the stain treatment additive. at least 0.2wt% of a stain treatment additive, wherein the stain treatment additive comprises an ester of glycerol and a C 16 to C 20 fatty acid, wherein the glycerol has been ethoxylated with from 6 to 10 mols of ethylene oxide, wherein the fatty acid comprises at least 50wt% isostearic acid, based on the total weight of fatty acid present, and wherein the ester comprises at least 20wt% mono-ester; and at least 10wt% in total of one or more surfactants or mixtures thereof, not including the stain treatment additive.
A display device comprising: a panel in which a plurality of touch electrodes are disposed in a display area, the touch electrodes including edge touch electrodes disposed at edges of the display area and center touch electrodes disposed inside the display area and surrounded by other touch electrodes; a touch sensing unit configured to supply a common voltage to the plurality of touch electrodes during an image display period and supply a touch signal to the plurality of touch electrodes during a touch sensing period to determine whether the panel is touched; and a touch assistance signal supply unit configured to supply a touch assistance signal to a touch assistance line during the touch sensing period, the touch assistance signal having the same phase and potential difference as a phase and a potential difference of the touch signal supplied to the plurality of touch electrodes during a touch sensing period, the touch assistance line being disposed in a non-display area outside the display area. a panel in which a plurality of touch electrodes are disposed in a display area, the touch electrodes including edge touch electrodes disposed at edges of the display area and center touch electrodes disposed inside the display area and surrounded by other touch electrodes; a touch sensing unit configured to supply a common voltage to the plurality of touch electrodes during an image display period and supply a touch signal to the plurality of touch electrodes during a touch sensing period to determine whether the panel is touched; and a touch assistance signal supply unit configured to supply a touch assistance signal to a touch assistance line during the touch sensing period, the touch assistance signal having the same phase and potential difference as a phase and a potential difference of the touch signal supplied to the plurality of touch electrodes during a touch sensing period, the touch assistance line being disposed in a non-display area outside the display area.
A method of implementing minor loop feedback fallback, comprising: determining a first minor loop feedback value using a first control mode; controlling a process control device at least partially based on the first minor loop feedback value; identifying the first minor loop feedback value being outside of a predetermined range or a failure of the first control mode; determining a second minor loop feedback value using a second control mode, characterised in that: the second control mode comprises determining an output pressure of a relay upstream of the process control device; and controlling the process control device at least partially based on the second minor loop feedback value. determining a first minor loop feedback value using a first control mode; controlling a process control device at least partially based on the first minor loop feedback value; identifying the first minor loop feedback value being outside of a predetermined range or a failure of the first control mode; determining a second minor loop feedback value using a second control mode, characterised in that: the second control mode comprises determining an output pressure of a relay upstream of the process control device; and controlling the process control device at least partially based on the second minor loop feedback value. the second control mode comprises determining an output pressure of a relay upstream of the process control device; and controlling the process control device at least partially based on the second minor loop feedback value.
A method for random access, the method being performed by a wireless device, the method comprising: transmitting a random access preamble to a network node; determining a valid starting subframe of a random access response window for monitoring a common search space for a random access response from the network node, wherein the valid subframe for starting the random access response window is determined according to 10 n f + ⌊ n s / 2 ⌋ mod T MPDCCH = 0, where n f denotes system frame number, where n s denotes slot number within radio frame, where T MPDCCH = R max · G, where R max is a maximum repetition level, and where G is an integer; and monitoring the common search space for the random access response only during the random access response window. transmitting a random access preamble to a network node; determining a valid starting subframe of a random access response window for monitoring a common search space for a random access response from the network node, wherein the valid subframe for starting the random access response window is determined according to 10 n f + ⌊ n s / 2 ⌋ mod T MPDCCH = 0, where n f denotes system frame number, where n s denotes slot number within radio frame, where T MPDCCH = R max · G, where R max is a maximum repetition level, and where G is an integer; and monitoring the common search space for the random access response only during the random access response window.
An electric actuator comprising: a housing (11, 12), a drive motor, a transmission assembly (34, 35), a rotary screw rod and a driving nut, the drive motor activating, via the transmission assembly, the rotary screw rod to rotate, rotation of the rotary screw rod bringing the driving nut to move axially along the rotary screw rod, the electric actuator further comprises a clutch device (31, 32, 33) provided between the transmission assembly and the rotary screw rod and configured to engage or disengage power transmission between the transmission assembly and the rotary screw rod; a self-locking device (43, 44) configured to produce a friction resistance against the rotary screw rod when the rotary screw rod rotates reversely, wherein the self-locking device comprises a release torsion spring for unlocking the self-locking device; and characterized in that the electric actuator further comprises a hand-rotatory release device provided on the housing, the hand-rotatory release device comprising a first driving member, a second driving member (51, 52) and a release rotary knob for activating the first driving member and the second driving member, the first driving member being connected to the clutch device, the second driving member being configured to connect the self-locking device, and the release rotary knob being turned to present an initial state and a completely released state, wherein in the course of switching from the initial state to the completely released state, the first driving member activates the clutch device to disengage the power connection, and the second driving member activates the release torsion spring to release. a clutch device (31, 32, 33) provided between the transmission assembly and the rotary screw rod and configured to engage or disengage power transmission between the transmission assembly and the rotary screw rod; a self-locking device (43, 44) configured to produce a friction resistance against the rotary screw rod when the rotary screw rod rotates reversely, wherein the self-locking device comprises a release torsion spring for unlocking the self-locking device; and characterized in that the electric actuator further comprises a hand-rotatory release device provided on the housing, the hand-rotatory release device comprising a first driving member, a second driving member (51, 52) and a release rotary knob for activating the first driving member and the second driving member, the first driving member being connected to the clutch device, the second driving member being configured to connect the self-locking device, and the release rotary knob being turned to present an initial state and a completely released state, wherein in the course of switching from the initial state to the completely released state, the first driving member activates the clutch device to disengage the power connection, and the second driving member activates the release torsion spring to release.
A breathing apparatus having a breathing gas source and a control unit which is adapted to provide breathing gas for a first, longer period of time (34, Tinsp) at an upper pressure level (30, Pinsp) and to provide breathing gas for a second, shorter period of time (35, Texsp) at a lower pressure level (31, Pexsp), wherein the breathing apparatus has sensors which detect measured values of the breathing gas (the flow and/or pressure and/or the volume of the breathing gas) at least intermittently, wherein the control unit provides the first, longer period of time (34, Tinsp) with the upper pressure level (30, Pinsp) for at least two spontaneous breathing phases of the patient (inspiration and an expiration) before the second, shorter period of time (35, Texsp) at a lower pressure level (31, Pexsp) is specified (in order to make possible a deepened expiration), wherein the breathing apparatus makes possible a spontaneous respiration of a patient at the upper pressure level (30, Pinsp) for at least two consecutive breathing phases and detects a tidal volume by sensor technology, characterized in that the control unit establishes a base level of the respiratory volume from the measured value of the tidal volume, wherein the control unit detects an expiratory volume exhaled by the patient during the second period of time (35, Texsp) and the length of the second period of time (35, Texsp) lasts until such time as the expiratory volume has substantially reached the value of the base level and wherein the expiratory volume does not fall below the value of the base level.
A method for manufacturing a composite preform from tape material, the method comprising: feeding a tape section (27, 56, 250) into a tape section guide that suspends the tape section (27, 56, 250) across a tooling surface so that a first end of the tape section (27, 56, 250) is initially disposed at a first position in the tape section guide and a second end of the tape section (27, 56, 250) is initially disposed at a second position in the tape section guide; providing relative movement between the tape section guide and the tooling surface to position the tape section (27, 56, 250) at a desired location and orientation relative to the tooling surface; moving the tape section (27, 56, 250) so that the first end is moved to a third position and the second end is moved to a fourth position in the tape section guide; and securing the tape section (27, 56, 250) to at least one of the tooling surface and a pre- existing tape section, whereby moving the tape section (27, 56, 250) includes gripping the tape section (27, 56, 250) with a gripping member and moving the gripping member along the tape section guide. feeding a tape section (27, 56, 250) into a tape section guide that suspends the tape section (27, 56, 250) across a tooling surface so that a first end of the tape section (27, 56, 250) is initially disposed at a first position in the tape section guide and a second end of the tape section (27, 56, 250) is initially disposed at a second position in the tape section guide; providing relative movement between the tape section guide and the tooling surface to position the tape section (27, 56, 250) at a desired location and orientation relative to the tooling surface; moving the tape section (27, 56, 250) so that the first end is moved to a third position and the second end is moved to a fourth position in the tape section guide; and securing the tape section (27, 56, 250) to at least one of the tooling surface and a pre- existing tape section, whereby moving the tape section (27, 56, 250) includes gripping the tape section (27, 56, 250) with a gripping member and moving the gripping member along the tape section guide.
A compound which is 2-(cyclohexylmethyl)- N -{2-[(2 S)-1-methylpyrrolidin-2-yl]ethyl}-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide difumarate monohydrate;
An electric vehicle chassis comprising a frame system, a steering motor damping system mounted on the frame system, a wheel system connected with the steering motor damping system, a steering system mounted on the frame system and a braking system mounted on the frame system, wherein the wheel system comprises a left front wheel using a hub motor, a left rear wheel using a hub motor, a right front wheel using a hub motor, and a right rear wheel using a hub motor; and the steering motor damping system comprises a left front steering damping motor, a right front steering damping motor, a left rear steering damping motor and a right rear steering damping motor; the left front steering damping motor and the right front steering damping motor are respectively disposed on a left side and a right side of a front end of the frame system, the left rear steering damping motor and the right rear steering damping motor are respectively disposed on the left side and the right side of a rear end of the frame system; the left front wheel is connected with the left front steering damping motor, the right front wheel is connected with the right front steering damping motor, the left rear wheel is connected with the left rear steering damping motor, the right rear wheel is connected with the right rear steering damping motor. characterized in that the frame system comprises two multi-cavity box stringers spaced and symmetrically placed and made of aluminum alloy and a multi-cavity beam assembly made of aluminum alloy and connected between the two multi-cavity box stringers, an inner of the multi-cavity box stringer is provided with a plurality of independent cavities, the multi-cavity beam assembly comprises a plurality of beams each of which the inner is provided with a plurality of independent cavities, the multi-cavity box stringer comprises a middle portion and curved portions disposed on both ends of the middle portion, the curved portions are curved upward from the middle portion toward positions diagonally above two opposite inner sides of the two multi-cavity box stringers.
Alignment harness for aligning a person, with a lifting device, characterised in that the alignment harness (1, 1.1) comprises a tubular arm receptacle, arranged on the front side in relation to the upper body of the person and open on the end side, for the insertion in each case of a forearm (9, 9.1) at an angle in relation to the upper arm (10, 10.1), from any side of the arm receptacle, as well as two lifting belts (4, 4.1; 4.2, 4.3), connected to the arm receptacle and at a spacing interval from one another, which is guided beneath the shoulders and onto the back of the person who is to be aligned, which can be connected to a lifting device
Method for determining the transmembrane pressure during extracorporeal blood treatment, in which blood flows, at a particular blood flow rate, via an arterial blood supply line of an extracorporeal blood circuit into the inlet of a first chamber of a dialyser which is divided into the first and a second chamber (3, 4) by a semipermeable membrane, and flows out of the outlet of the first chamber of the dialyser via a venous blood return line, and in which dialysate flows into the inlet of the second chamber of the dialyser via a dialysate supply line and flows out of the outlet of the second chamber of the dialyser via a dialysate removal line, fluid being removed from the blood at a particular flow rate via the membrane of the dialyser, comprising the following method steps: measuring the pressure on the blood side at the inlet or outlet of the first chamber of the dialyser and on the dialysate side at the inlet or outlet of the second chamber of the dialyser, and calculating the transmembrane pressure on the basis of the pressure measured on the blood side and on the dialysate side, characterised in that a variable is determined which correlates with the viscosity of the blood, in that a correction value for the transmembrane pressure is determined which is dependent on a variable which correlates with the viscosity of the blood, and in that the transmembrane pressure is calculated on the basis of the pressure measured on the blood side and on the dialysate side and on the basis of the correction value for the transmembrane pressure. measuring the pressure on the blood side at the inlet or outlet of the first chamber of the dialyser and on the dialysate side at the inlet or outlet of the second chamber of the dialyser, and calculating the transmembrane pressure on the basis of the pressure measured on the blood side and on the dialysate side, characterised in that a variable is determined which correlates with the viscosity of the blood, in that a correction value for the transmembrane pressure is determined which is dependent on a variable which correlates with the viscosity of the blood, and in that the transmembrane pressure is calculated on the basis of the pressure measured on the blood side and on the dialysate side and on the basis of the correction value for the transmembrane pressure.
A composition comprising larixol and further at least one of the components to, which is not larixol, 5 wherein: denotes at least one skin lightening agent; denotes at least one sun protection factor; denotes at least one anti-oxidant; denotes at least one anti-inflammatory agent; and denotes at least one desquamating agent. denotes at least one skin lightening agent; denotes at least one sun protection factor; denotes at least one anti-oxidant; denotes at least one anti-inflammatory agent; and denotes at least one desquamating agent.
Apparatus for dressing a wound (100, 400) for topical negative pressure therapy, comprising: a wound contact layer; a gas impermeable sealing layer comprising at least one orifice; a porous layer between the wound contact layer and sealing layer; an absorbent layer over the sealing layer for absorbing wound exudate; a liquid impermeable, gas permeable filter layer over the absorbent layer, wherein the filter layer is between the absorbent layer and an overlying cover layer; and a pump element, located between the cover layer and sealing layer, comprising an inlet in fluid communication with the sealing layer orifice and an outlet in fluid communication with the absorbent layer. a wound contact layer; a gas impermeable sealing layer comprising at least one orifice; a porous layer between the wound contact layer and sealing layer; an absorbent layer over the sealing layer for absorbing wound exudate; a liquid impermeable, gas permeable filter layer over the absorbent layer, wherein the filter layer is between the absorbent layer and an overlying cover layer; and a pump element, located between the cover layer and sealing layer, comprising an inlet in fluid communication with the sealing layer orifice and an outlet in fluid communication with the absorbent layer.