A medical system comprising: a valve clip comprising a deformable wire configured to engage valve leaflets of a patient, wherein the deformable wire extends from a first wire portion to a second wire portion; and a catheter configured to introduce the valve clip adjacent a native heart valve in a patient, the catheter comprising: a handle comprising a plurality of control members; an elongate body defining a lumen, wherein the elongate body extends from a proximal end mechanically coupled to the handle to a distal portion comprising a distal opening; a first delivery device (1 10A) operatively coupled to at least one control member of the plurality of control members and extending through the lumen to the distal opening, wherein the first delivery device is configured to be releasably coupled to the first wire portion and moveable relative to the distal opening of the elongate body; and a second delivery device operatively coupled to at least one control member of the plurality of control members and extending through the lumen to the distal opening, wherein the second delivery device is configured to be releasably coupled to the second wire portion, wherein the first and second delivery device are configured to move the valve clip between an extended configuration and a contracted configuration to engage the valve leaflets. a valve clip comprising a deformable wire configured to engage valve leaflets of a patient, wherein the deformable wire extends from a first wire portion to a second wire portion; and a catheter configured to introduce the valve clip adjacent a native heart valve in a patient, the catheter comprising: a handle comprising a plurality of control members; an elongate body defining a lumen, wherein the elongate body extends from a proximal end mechanically coupled to the handle to a distal portion comprising a distal opening; a first delivery device (1 10A) operatively coupled to at least one control member of the plurality of control members and extending through the lumen to the distal opening, wherein the first delivery device is configured to be releasably coupled to the first wire portion and moveable relative to the distal opening of the elongate body; and a second delivery device operatively coupled to at least one control member of the plurality of control members and extending through the lumen to the distal opening, wherein the second delivery device is configured to be releasably coupled to the second wire portion, a handle comprising a plurality of control members; an elongate body defining a lumen, wherein the elongate body extends from a proximal end mechanically coupled to the handle to a distal portion comprising a distal opening; a first delivery device (1 10A) operatively coupled to at least one control member of the plurality of control members and extending through the lumen to the distal opening, wherein the first delivery device is configured to be releasably coupled to the first wire portion and moveable relative to the distal opening of the elongate body; and a second delivery device operatively coupled to at least one control member of the plurality of control members and extending through the lumen to the distal opening, wherein the second delivery device is configured to be releasably coupled to the second wire portion, wherein the first and second delivery device are configured to move the valve clip between an extended configuration and a contracted configuration to engage the valve leaflets.