A closure assembly for a flexible container, comprising: a connector assembly, mountable at an opening of the flexible container, configured to provide a fluid path through the opening of the flexible container, comprising: a male connector member, comprising a first tubular body having a first proximal end portion and a first distal end portion along a first central axis, and a first flange portion protruding radially outwards at said first proximal end portion, and a female connector member, comprising a second tubular body having a second proximal end portion and a second distal end portion along a second central axis, a second flange portion protruding radially outwards at said second proximal end portion and at least one diametrically traversing internal support member at said second distal end portion, said female connector member being configured to coaxially matingly and interlockingly engage with said male connector member, so as to securingly clamp at least a peripheral edge portion of the opening of the flexible container between said first and second flange portion (138, 114); a plug member, comprising a third cylindrical body having a third proximal end portion and a third distal end portion along a third central axis, at least two radially opposed locking members (148a, 148b), each one protruding axially away from said distal end portion so as to lockingly engage with said internal support member during use, said plug member being configured to matingly and sealingly engage with said male connector member and lockingly engage with said female connector member during use. a connector assembly, mountable at an opening of the flexible container, configured to provide a fluid path through the opening of the flexible container, comprising: a male connector member, comprising a first tubular body having a first proximal end portion and a first distal end portion along a first central axis, and a first flange portion protruding radially outwards at said first proximal end portion, and a female connector member, comprising a second tubular body having a second proximal end portion and a second distal end portion along a second central axis, a second flange portion protruding radially outwards at said second proximal end portion and at least one diametrically traversing internal support member at said second distal end portion, said female connector member being configured to coaxially matingly and interlockingly engage with said male connector member, so as to securingly clamp at least a peripheral edge portion of the opening of the flexible container between said first and second flange portion (138, 114); a male connector member, comprising a first tubular body having a first proximal end portion and a first distal end portion along a first central axis, and a first flange portion protruding radially outwards at said first proximal end portion, and a female connector member, comprising a second tubular body having a second proximal end portion and a second distal end portion along a second central axis, a second flange portion protruding radially outwards at said second proximal end portion and at least one diametrically traversing internal support member at said second distal end portion, said female connector member being configured to coaxially matingly and interlockingly engage with said male connector member, so as to securingly clamp at least a peripheral edge portion of the opening of the flexible container between said first and second flange portion (138, 114); a plug member, comprising a third cylindrical body having a third proximal end portion and a third distal end portion along a third central axis, at least two radially opposed locking members (148a, 148b), each one protruding axially away from said distal end portion so as to lockingly engage with said internal support member during use, said plug member being configured to matingly and sealingly engage with said male connector member and lockingly engage with said female connector member during use.