A machining method of a hybrid CNC machining center, comprising steps of: providing a hybrid CNC machining center including at least a cutting tool head, a laser cladding tool head, and a computer numerical control unit, wherein the cutting tool head and the laser cladding tool head are alternately installed in a tool holder of the hybrid CNC machining center; and processing a first cutting operation, wherein the cutting tool head is configured to cut at least a machined surface of a work-piece; characterized in that: the machining method further comprising steps of: processing a cladding operation, wherein the laser cladding tool head is configured to clad the machined surface and further includes a temperature sensor and a camera, and during the step of processing the cladding operation, firstly detecting a temperature of a molten pool of the machined surface by the temperature sensor, and providing the detected temperature of the molten pool to the computer numerical control unit, wherein if the temperature of the molten pool is under a default temperature, a power of the laser cladding tool head is increased; and if the temperature of the molten pool is over the default temperature, the power of the laser cladding tool head is decreased; and then detecting a lightness and profile of the molten pool of the machined surface by the camera, and providing the detected lightness and profile of the molten pool to the computer numerical control unit, wherein if the lightness and profile of the molten pool is under a default condition, the power of the laser cladding tool head is increased; and if the lightness and profile of the molten pool is over the default condition, the power of the laser cladding tool head is decreased. providing a hybrid CNC machining center including at least a cutting tool head, a laser cladding tool head, and a computer numerical control unit, wherein the cutting tool head and the laser cladding tool head are alternately installed in a tool holder of the hybrid CNC machining center; and processing a first cutting operation, wherein the cutting tool head is configured to cut at least a machined surface of a work-piece; characterized in that: the machining method further comprising steps of: processing a cladding operation, wherein the laser cladding tool head is configured to clad the machined surface and further includes a temperature sensor and a camera, and during the step of processing the cladding operation, firstly detecting a temperature of a molten pool of the machined surface by the temperature sensor, and providing the detected temperature of the molten pool to the computer numerical control unit, wherein if the temperature of the molten pool is under a default temperature, a power of the laser cladding tool head is increased; and if the temperature of the molten pool is over the default temperature, the power of the laser cladding tool head is decreased; and then detecting a lightness and profile of the molten pool of the machined surface by the camera, and providing the detected lightness and profile of the molten pool to the computer numerical control unit, wherein if the lightness and profile of the molten pool is under a default condition, the power of the laser cladding tool head is increased; and if the lightness and profile of the molten pool is over the default condition, the power of the laser cladding tool head is decreased.