Absorbable isocyanates of Formula or: Wherein: Each X is independently selected from: - OCH 2 CO- (glycolic ester moiety) - OCH(CH 3)CO- (lactic ester moiety) - OCH 2 CH 2 OCH 2 CO- (dioxanone ester moiety) - OCH 2 CH 2 CH 2 CH 2 CH 2 CO- (caprolactone ester moiety); - O(CH 2) y CO- or, where y is one of the numbers 2, 3, 4, and 6-24 inclusive; or - O(CH 2 CH 2 O) m CH 2 CO-; where m is integer between 2-24 inclusive; and, And wherein p is independently selected from 0 to 6 inclusive; and, Each X' is independently selected from: - CH 2 COO- (glycolic moiety) - CH(CH 3)COO- (lactic moiety) - CH 2 CH 2 OCH 2 COO- (dioxanone moiety) - CH 2 CH 2 CH 2 CH 2 CH 2 COO- (caprolactone moiety) - (CH 2) y COO- or, where y is one of the numbers 2, 3, 4, and 6-24 inclusive; or - (CH 2 CH 2 O) m CH 2 COO-; where m is integer between 2-24 inclusive; Each Y is independently selected from: - COCH 2 O- (glycolic moiety) - COCH(CH 3)O- (lactic moiety) - COCH 2 OCH 2 CH 2 O- (dioxanone moiety) - COCH 2 CH 2 CH 2 CH 2 CH 2 O- (caprolactone moiety) - CO(CH 2) y O- or, where y is one of the numbers 2, 3, 4, and 6-24 inclusive; or - CO(CH 2 CH 2 O) m CH 2 O-; where m is integer between 2-24 inclusive; R is a residue of an amino acid; and R'* is a residue of a diol wherein R'* is alkyl, aryl or arylalkyl. Each X is independently selected from: - OCH 2 CO- (glycolic ester moiety) - OCH(CH 3)CO- (lactic ester moiety) - OCH 2 CH 2 OCH 2 CO- (dioxanone ester moiety) - OCH 2 CH 2 CH 2 CH 2 CH 2 CO- (caprolactone ester moiety); - O(CH 2) y CO- or, where y is one of the numbers 2, 3, 4, and 6-24 inclusive; or - O(CH 2 CH 2 O) m CH 2 CO-; where m is integer between 2-24 inclusive; and, And wherein p is independently selected from 0 to 6 inclusive; and, - OCH 2 CO- (glycolic ester moiety) - OCH(CH 3)CO- (lactic ester moiety) - OCH 2 CH 2 OCH 2 CO- (dioxanone ester moiety) - OCH 2 CH 2 CH 2 CH 2 CH 2 CO- (caprolactone ester moiety); - O(CH 2) y CO- or, where y is one of the numbers 2, 3, 4, and 6-24 inclusive; or - O(CH 2 CH 2 O) m CH 2 CO-; where m is integer between 2-24 inclusive; and, And wherein p is independently selected from 0 to 6 inclusive; and, Each X' is independently selected from: - CH 2 COO- (glycolic moiety) - CH(CH 3)COO- (lactic moiety) - CH 2 CH 2 OCH 2 COO- (dioxanone moiety) - CH 2 CH 2 CH 2 CH 2 CH 2 COO- (caprolactone moiety) - (CH 2) y COO- or, where y is one of the numbers 2, 3, 4, and 6-24 inclusive; or - (CH 2 CH 2 O) m CH 2 COO-; where m is integer between 2-24 inclusive; - CH 2 COO- (glycolic moiety) - CH(CH 3)COO- (lactic moiety) - CH 2 CH 2 OCH 2 COO- (dioxanone moiety) - CH 2 CH 2 CH 2 CH 2 CH 2 COO- (caprolactone moiety) - (CH 2) y COO- or, where y is one of the numbers 2, 3, 4, and 6-24 inclusive; or - (CH 2 CH 2 O) m CH 2 COO-; where m is integer between 2-24 inclusive; Each Y is independently selected from: - COCH 2 O- (glycolic moiety) - COCH(CH 3)O- (lactic moiety) - COCH 2 OCH 2 CH 2 O- (dioxanone moiety) - COCH 2 CH 2 CH 2 CH 2 CH 2 O- (caprolactone moiety) - CO(CH 2) y O- or, where y is one of the numbers 2, 3, 4, and 6-24 inclusive; or - CO(CH 2 CH 2 O) m CH 2 O-; where m is integer between 2-24 inclusive; R is a residue of an amino acid; and R'* is a residue of a diol wherein R'* is alkyl, aryl or arylalkyl. - COCH 2 O- (glycolic moiety) - COCH(CH 3)O- (lactic moiety) - COCH 2 OCH 2 CH 2 O- (dioxanone moiety) - COCH 2 CH 2 CH 2 CH 2 CH 2 O- (caprolactone moiety) - CO(CH 2) y O- or, where y is one of the numbers 2, 3, 4, and 6-24 inclusive; or - CO(CH 2 CH 2 O) m CH 2 O-; where m is integer between 2-24 inclusive;