A method for production of diesel from a hydrocarbon mixture having an initial T95 distillation temperature within the range between 360°C and 420°C, using a continuous reactor system which comprises the following features: the reactor system temperature is within the range of 350°C and 450°C, the hydrogen partial pressure within the reactor system is within the range of 60 bar and 80 bar, the reactor system comprises a hydrodesulfurization zone comprising hydrodesulfurization catalyst, the reactor system further comprises a hydrocracking zone comprising a hydrocracking catalyst, wherein said method comprises the following sequential steps: a) preparation of a hydrocarbon mixture by admixing a diesel range stream having a T95 distillation temperature of maximum 360°C with a heavy stream having a T95 distillation temperature higher than 360°C, the weight ratio of diesel range stream to the heavy stream being within the range between 10:0.5 and 10:1.5, and the initial T95 distillation temperature of the hydrocarbon mixture is within the range between 375°C and 395°C; b) feeding the hydrocarbon mixture into the reactor system, c) forwarding the hydrocarbon mixture such that the hydrocarbon mixture flows through the hydrodesulfurization zone, d) forwarding the hydrocarbon mixture such that said hydrocarbon mixture flows through the hydrocracking zone. the reactor system temperature is within the range of 350°C and 450°C, the hydrogen partial pressure within the reactor system is within the range of 60 bar and 80 bar, the reactor system comprises a hydrodesulfurization zone comprising hydrodesulfurization catalyst, the reactor system further comprises a hydrocracking zone comprising a hydrocracking catalyst, wherein said method comprises the following sequential steps: a) preparation of a hydrocarbon mixture by admixing a diesel range stream having a T95 distillation temperature of maximum 360°C with a heavy stream having a T95 distillation temperature higher than 360°C, the weight ratio of diesel range stream to the heavy stream being within the range between 10:0.5 and 10:1.5, and the initial T95 distillation temperature of the hydrocarbon mixture is within the range between 375°C and 395°C; b) feeding the hydrocarbon mixture into the reactor system, c) forwarding the hydrocarbon mixture such that the hydrocarbon mixture flows through the hydrodesulfurization zone, d) forwarding the hydrocarbon mixture such that said hydrocarbon mixture flows through the hydrocracking zone. a) preparation of a hydrocarbon mixture by admixing a diesel range stream having a T95 distillation temperature of maximum 360°C with a heavy stream having a T95 distillation temperature higher than 360°C, the weight ratio of diesel range stream to the heavy stream being within the range between 10:0.5 and 10:1.5, and the initial T95 distillation temperature of the hydrocarbon mixture is within the range between 375°C and 395°C; b) feeding the hydrocarbon mixture into the reactor system, c) forwarding the hydrocarbon mixture such that the hydrocarbon mixture flows through the hydrodesulfurization zone, d) forwarding the hydrocarbon mixture such that said hydrocarbon mixture flows through the hydrocracking zone.