A pipette tip dispensing device, comprising: a) a sleeve; b) an activator plate within the sleeve; c) a distal barrier plate within the sleeve disposed opposite to and spaced away from the activator plate; d) two or more threaded rods in connection with the activator plate and distal barrier plate; e) a plurality of nested pipette tip units between the activator and barrier plates, wherein: (i) each unit is aligned with a channel in the distal barrier plate, and (ii) the distal barrier plate comprises: a plurality of channels, wherein each channel has a diameter larger than the widest portion of a pipette tip; a substantially flat top surface, a substantially flat bottom surface that comprises a plurality of tails around some or all of the channels, wherein the tails extend in a perpendicular orientation from the flat bottom surface; wherein the tails around each channel are able to contact and deflect outwards against the proximal portion of a pipette tip when a pipette tip is dispensed and passes by the tails, thereby imparting a frictional force on the pipette tip when it is dispensed; the plurality of channels comprises two or more different subsets of channels and each subset of channels has a different frictional profile from another subset and is configured to eject pipette tips at different times; and f) an actuating motor in effective connection with the threaded rods, able to rotate the threaded rods whereby the activator plate and the distal barrier plate are translated towards one another thereby applying an axial force on the array of pipette tips to eject the array of pipette tips into respective receptacles in a loading block. a) a sleeve; b) an activator plate within the sleeve; c) a distal barrier plate within the sleeve disposed opposite to and spaced away from the activator plate; d) two or more threaded rods in connection with the activator plate and distal barrier plate; e) a plurality of nested pipette tip units between the activator and barrier plates, wherein: (i) each unit is aligned with a channel in the distal barrier plate, and (ii) the distal barrier plate comprises: a plurality of channels, wherein each channel has a diameter larger than the widest portion of a pipette tip; a substantially flat top surface, a substantially flat bottom surface that comprises a plurality of tails around some or all of the channels, wherein the tails extend in a perpendicular orientation from the flat bottom surface; wherein the tails around each channel are able to contact and deflect outwards against the proximal portion of a pipette tip when a pipette tip is dispensed and passes by the tails, thereby imparting a frictional force on the pipette tip when it is dispensed; the plurality of channels comprises two or more different subsets of channels and each subset of channels has a different frictional profile from another subset and is configured to eject pipette tips at different times; and (i) each unit is aligned with a channel in the distal barrier plate, and (ii) the distal barrier plate comprises: a plurality of channels, wherein each channel has a diameter larger than the widest portion of a pipette tip; a substantially flat top surface, a substantially flat bottom surface that comprises a plurality of tails around some or all of the channels, wherein the tails extend in a perpendicular orientation from the flat bottom surface; wherein the tails around each channel are able to contact and deflect outwards against the proximal portion of a pipette tip when a pipette tip is dispensed and passes by the tails, thereby imparting a frictional force on the pipette tip when it is dispensed; the plurality of channels comprises two or more different subsets of channels and each subset of channels has a different frictional profile from another subset and is configured to eject pipette tips at different times; and a plurality of channels, wherein each channel has a diameter larger than the widest portion of a pipette tip; a substantially flat top surface, a substantially flat bottom surface that comprises a plurality of tails around some or all of the channels, wherein the tails extend in a perpendicular orientation from the flat bottom surface; wherein the tails around each channel are able to contact and deflect outwards against the proximal portion of a pipette tip when a pipette tip is dispensed and passes by the tails, thereby imparting a frictional force on the pipette tip when it is dispensed; the plurality of channels comprises two or more different subsets of channels and each subset of channels has a different frictional profile from another subset and is configured to eject pipette tips at different times; and f) an actuating motor in effective connection with the threaded rods, able to rotate the threaded rods whereby the activator plate and the distal barrier plate are translated towards one another thereby applying an axial force on the array of pipette tips to eject the array of pipette tips into respective receptacles in a loading block.