A high pressure polymerization process to form an ethylene-based polymer, the process comprising at least the following step: polymerizing a reaction mixture comprising ethylene and at least one comonomer, using a reactor system comprising a reactor configuration, and the following: at least two reaction zones, a first reaction zone (reaction zone 1) and an ith reaction zone (reaction zone i where i ≥ 2), at least two ethylene-based feed streams, each feed stream comprising a percentage of the total make-up ethylene fed to the polymerization process, and wherein a first ethylene-based feed stream is sent to reaction zone 1 and a second ethylene-based feed stream is sent to reaction zone i; a control system to control the percentage of the total make-up ethylene in the ethylene-based feed stream sent to reaction zone 1, and the percentage of the total make-up ethylene in the ethylene-based feed stream sent to reaction zone i, and wherein is the mole percent of at least one comonomer fed to the first reaction zone minus the mole percent of the comonomer fed to the ith reaction zone divided by the average mole percent of the comonomer in all ethylene-based feeds to the reactor configuration and meets the following: Equation 1: 0.23 ln r1 − 2.16 ≤ Q ≤ − 0.25 ln r1 + 2.15 and one of Equation 2 or Equation 3: Q < 0.51 ln r1 − 1.32 or Q > - 0.51ln + 1.32 (Equation 3); and wherein the comonomer has a reactivity ratio as follow: 0.3 ≤ r1 ≤ 5.0, and a boiling point (1 atm) ≤ 150°C. polymerizing a reaction mixture comprising ethylene and at least one comonomer, using a reactor system comprising a reactor configuration, and the following: at least two reaction zones, a first reaction zone (reaction zone 1) and an ith reaction zone (reaction zone i where i ≥ 2), at least two ethylene-based feed streams, each feed stream comprising a percentage of the total make-up ethylene fed to the polymerization process, and wherein a first ethylene-based feed stream is sent to reaction zone 1 and a second ethylene-based feed stream is sent to reaction zone i; a control system to control the percentage of the total make-up ethylene in the ethylene-based feed stream sent to reaction zone 1, and the percentage of the total make-up ethylene in the ethylene-based feed stream sent to reaction zone i, and at least two reaction zones, a first reaction zone (reaction zone 1) and an ith reaction zone (reaction zone i where i ≥ 2), at least two ethylene-based feed streams, each feed stream comprising a percentage of the total make-up ethylene fed to the polymerization process, and wherein a first ethylene-based feed stream is sent to reaction zone 1 and a second ethylene-based feed stream is sent to reaction zone i; a control system to control the percentage of the total make-up ethylene in the ethylene-based feed stream sent to reaction zone 1, and the percentage of the total make-up ethylene in the ethylene-based feed stream sent to reaction zone i, and wherein is the mole percent of at least one comonomer fed to the first reaction zone minus the mole percent of the comonomer fed to the ith reaction zone divided by the average mole percent of the comonomer in all ethylene-based feeds to the reactor configuration and meets the following: Equation 1: 0.23 ln r1 − 2.16 ≤ Q ≤ − 0.25 ln r1 + 2.15 and one of Equation 2 or Equation 3: Q < 0.51 ln r1 − 1.32 or Q > - 0.51ln + 1.32 (Equation 3); and wherein the comonomer has a reactivity ratio as follow: 0.3 ≤ r1 ≤ 5.0, and a boiling point (1 atm) ≤ 150°C.