A system for monitoring health status of a patient, the system comprising: a physiological sensor circuit including a sense amplifier circuit to sense one or more physiological signals; a health status analyzer circuit coupled to the physiological sensor circuit, the health status analyzer circuit including: a risk stratifier circuit to produce a first risk indication of the patient developing a first disease and a second risk indication of the patient developing a different second disease; a first detector circuit to detect the first disease from the one or more physiological signals; a second detector circuit to detect the second disease from the one or more physiological signals; and a blending circuit to generate a composite health status indicator using the detections of the first and second diseases and the first and second risk indications; wherein the first risk indication includes a first risk score and a second risk indication includes a second risk score, and wherein: the first detector circuit is to detect the first disease including generate a first detection score indicating a confidence of detecting the first disease; the second detector circuit is to detect the second disease including generate a second detection score indicating a confidence of detecting the second disease; and the blending circuit is to produce the composite health status indicator including a composite detection score using a combination of the first and second detection scores each weighted by the respective first and second risk scores. a physiological sensor circuit including a sense amplifier circuit to sense one or more physiological signals; a health status analyzer circuit coupled to the physiological sensor circuit, the health status analyzer circuit including: a risk stratifier circuit to produce a first risk indication of the patient developing a first disease and a second risk indication of the patient developing a different second disease; a first detector circuit to detect the first disease from the one or more physiological signals; a second detector circuit to detect the second disease from the one or more physiological signals; and a blending circuit to generate a composite health status indicator using the detections of the first and second diseases and the first and second risk indications; wherein the first risk indication includes a first risk score and a second risk indication includes a second risk score, and wherein: the first detector circuit is to detect the first disease including generate a first detection score indicating a confidence of detecting the first disease; the second detector circuit is to detect the second disease including generate a second detection score indicating a confidence of detecting the second disease; and the blending circuit is to produce the composite health status indicator including a composite detection score using a combination of the first and second detection scores each weighted by the respective first and second risk scores. a risk stratifier circuit to produce a first risk indication of the patient developing a first disease and a second risk indication of the patient developing a different second disease; a first detector circuit to detect the first disease from the one or more physiological signals; a second detector circuit to detect the second disease from the one or more physiological signals; and a blending circuit to generate a composite health status indicator using the detections of the first and second diseases and the first and second risk indications; wherein the first risk indication includes a first risk score and a second risk indication includes a second risk score, and wherein: the first detector circuit is to detect the first disease including generate a first detection score indicating a confidence of detecting the first disease; the second detector circuit is to detect the second disease including generate a second detection score indicating a confidence of detecting the second disease; and the blending circuit is to produce the composite health status indicator including a composite detection score using a combination of the first and second detection scores each weighted by the respective first and second risk scores. the first detector circuit is to detect the first disease including generate a first detection score indicating a confidence of detecting the first disease; the second detector circuit is to detect the second disease including generate a second detection score indicating a confidence of detecting the second disease; and the blending circuit is to produce the composite health status indicator including a composite detection score using a combination of the first and second detection scores each weighted by the respective first and second risk scores.