A method for configuring a surgical guide (9, 28, 34, 44) and an associated implant (5, 27, 33, 43) for maxillofacial osteosynthesis, the method comprising: accessing data indicative of a pre-operative maxillofacial anatomy of a patient and generating a three-dimensional model of said anatomy using said data; simulating an osteotomy (3, 7, 12, 13, 22, 29) on the three-dimensional model of the pre-operative maxillofacial anatomy, said simulated osteotomy defining at least one cut that results in a second bone portion (2, 25, 31) that is separated from a first bone portion (1, 24, 30), said osteotomy resulting in an absence of any bone coupling the first and second bone portions together; arranging the second bone portion in relation to the first bone portion to generate a modified three-dimensional model indicative of a desired post-operative orientation of the first and second bone portions, said arrangement comprising at least one of a translation and a rotation of the second bone portion in relation to the first bone portion; defining, on the modified three-dimensional model, a first plurality of attachment points (4, 32) for the implant on the first bone portion and a second plurality of attachment points (4, 32) for the implant on the second bone portion, wherein said first and second pluralities of attachment points are defined on the modified three-dimensional model based on at least one location of one or more anatomical features (51, 53) of the patient; determining a monolithic three-dimensional structure for the implant that couples the first and second plurality of attachment points in the modified three-dimensional model, wherein the monolithic three-dimensional structure for the implant has a shape that varies in each of three dimensions to arrange the second bone portion relative to the first bone portion in accordance with the desired post-operative orientation, each of at least one of the attachment points corresponding to an aperture for a bone fixation device in said structure for the implant; mapping the first and second plurality of attachment points to corresponding locations on the three-dimensional model of the pre-operative maxillofacial anatomy; and determining a monolithic three-dimensional structure for the surgical guide that couples the corresponding locations in the three-dimensional model of the pre-operative maxillofacial anatomy, wherein each of at least one of the corresponding locations corresponds to a guide aperture in said structure for the surgical guide. accessing data indicative of a pre-operative maxillofacial anatomy of a patient and generating a three-dimensional model of said anatomy using said data; simulating an osteotomy (3, 7, 12, 13, 22, 29) on the three-dimensional model of the pre-operative maxillofacial anatomy, said simulated osteotomy defining at least one cut that results in a second bone portion (2, 25, 31) that is separated from a first bone portion (1, 24, 30), said osteotomy resulting in an absence of any bone coupling the first and second bone portions together; arranging the second bone portion in relation to the first bone portion to generate a modified three-dimensional model indicative of a desired post-operative orientation of the first and second bone portions, said arrangement comprising at least one of a translation and a rotation of the second bone portion in relation to the first bone portion; defining, on the modified three-dimensional model, a first plurality of attachment points (4, 32) for the implant on the first bone portion and a second plurality of attachment points (4, 32) for the implant on the second bone portion, wherein said first and second pluralities of attachment points are defined on the modified three-dimensional model based on at least one location of one or more anatomical features (51, 53) of the patient; determining a monolithic three-dimensional structure for the implant that couples the first and second plurality of attachment points in the modified three-dimensional model, wherein the monolithic three-dimensional structure for the implant has a shape that varies in each of three dimensions to arrange the second bone portion relative to the first bone portion in accordance with the desired post-operative orientation, each of at least one of the attachment points corresponding to an aperture for a bone fixation device in said structure for the implant; mapping the first and second plurality of attachment points to corresponding locations on the three-dimensional model of the pre-operative maxillofacial anatomy; and determining a monolithic three-dimensional structure for the surgical guide that couples the corresponding locations in the three-dimensional model of the pre-operative maxillofacial anatomy, wherein each of at least one of the corresponding locations corresponds to a guide aperture in said structure for the surgical guide.