A center frame positioning system for an agricultural sprayer vehicle, the system comprising: one or more controllable, variable pressure actuators (152, 252) that each are configured to operably exert a force on a suspended center frame of the agricultural sprayer vehicle, wherein a sprayer boom is attached to the suspended center frame and wherein the one or more actuators (152, 252) comprises an air spring (352a, 352b) that provides variable force in the form of air pressure; one or more sensors (S 1 -S N collectively 102) that provide real-time center frame position data indicative of a detected position of the suspended center frame in real time, including an air spring force detecting sensor (354a, 354b); and a control device that: receives the center frame position data; compares a detected air spring force in the respective one or more air springs (352a, 352b) to a preset target force for the respective one or more air springs; and provides one or more actuator adjustment commands to adjust the force exerted on the suspended center frame, if needed, for the respective one or more air springs (352a, 352b) based at least on the comparing of the detected air spring force to the preset target force; wherein the force exerted on the suspended center frame by the one or more actuators (152, 252) is adjusted in real-time as a result of the one or more actuator adjustment commands; and wherein adjustment of the force exerted on the suspended center frame results in adjustment of a distance (d) of the sprayer boom from the ground. one or more controllable, variable pressure actuators (152, 252) that each are configured to operably exert a force on a suspended center frame of the agricultural sprayer vehicle, wherein a sprayer boom is attached to the suspended center frame and wherein the one or more actuators (152, 252) comprises an air spring (352a, 352b) that provides variable force in the form of air pressure; one or more sensors (S 1 -S N collectively 102) that provide real-time center frame position data indicative of a detected position of the suspended center frame in real time, including an air spring force detecting sensor (354a, 354b); and a control device that: receives the center frame position data; compares a detected air spring force in the respective one or more air springs (352a, 352b) to a preset target force for the respective one or more air springs; and provides one or more actuator adjustment commands to adjust the force exerted on the suspended center frame, if needed, for the respective one or more air springs (352a, 352b) based at least on the comparing of the detected air spring force to the preset target force; receives the center frame position data; compares a detected air spring force in the respective one or more air springs (352a, 352b) to a preset target force for the respective one or more air springs; and provides one or more actuator adjustment commands to adjust the force exerted on the suspended center frame, if needed, for the respective one or more air springs (352a, 352b) based at least on the comparing of the detected air spring force to the preset target force; wherein the force exerted on the suspended center frame by the one or more actuators (152, 252) is adjusted in real-time as a result of the one or more actuator adjustment commands; and wherein adjustment of the force exerted on the suspended center frame results in adjustment of a distance (d) of the sprayer boom from the ground.