mhurhangee/ep-ind-claims huggingface dataset:
A probe having a structure satisfying Formula II wherein ERG, if present, is S 2 OH, or an anionic form thereof; P 2, or an anionic form thereof; a halogen; or -OPh-CHz-ONOz; EBG has a structure satisfying Formula IIA EBG Linker a comprises an aliphatic group, a heteroaliphatic group, an aromatic group, an aliphatic-aromatic group, a heteroaliphatic-aromatic group, a heteroaromatic group, an aliphatic-heteroaromatic group, or a heteroaliphatic-heteroaromatic group; Linker b, if present, independently comprises an aliphatic group, a heteroaliphatic group, an aromatic group, an aliphatic-aromatic group, a heteroaliphatic-aromatic group, a heteroaromatic group, an aliphatic-heteroaromatic group, or a heteroaliphatic-heteroaromatic group; Linker c comprises an aliphatic group, a heteroaliphatic group, an aromatic group, an aliphatic-aromatic group, a heteroaliphatic-aromatic group, a heteroaromatic group, an aliphatic-heteroaromatic group, or a heteroaliphatic-heteroaromatic group; R, if present, is a group comprising a carbamate or a carbonate;each Tag, if present, independently is a fluorophore, a binding partner of an affinity-based binding pair, a quantum dot, or a dye; each p Tag, which is present if a Tag is not present, independently is an azide or alkyne; and each of n, p, and q independently is 0 or 1; and m is 1. ERG, if present, is S 2 OH, or an anionic form thereof; P 2, or an anionic form thereof; a halogen; or -OPh-CHz-ONOz; EBG has a structure satisfying Formula IIA EBG Linker a comprises an aliphatic group, a heteroaliphatic group, an aromatic group, an aliphatic-aromatic group, a heteroaliphatic-aromatic group, a heteroaromatic group, an aliphatic-heteroaromatic group, or a heteroaliphatic-heteroaromatic group; Linker b, if present, independently comprises an aliphatic group, a heteroaliphatic group, an aromatic group, an aliphatic-aromatic group, a heteroaliphatic-aromatic group, a heteroaromatic group, an aliphatic-heteroaromatic group, or a heteroaliphatic-heteroaromatic group; Linker c comprises an aliphatic group, a heteroaliphatic group, an aromatic group, an aliphatic-aromatic group, a heteroaliphatic-aromatic group, a heteroaromatic group, an aliphatic-heteroaromatic group, or a heteroaliphatic-heteroaromatic group; R, if present, is a group comprising a carbamate or a carbonate;each Tag, if present, independently is a fluorophore, a binding partner of an affinity-based binding pair, a quantum dot, or a dye; each p Tag, which is present if a Tag is not present, independently is an azide or alkyne; and each of n, p, and q independently is 0 or 1; and m is 1.
A compound of formula: wherein, each of R 1, R 2, and R 3 is independently hydrogen, alkyl or substituted alkyl, alkoxy or substituted alkoxy, heteroalkyl or substituted heteroalkyl, or heteroaryl or substituted heteroaryl; and Z is alkyl or substituted alkyl, alkoxy or substituted alkoxy, heteroalkyl or substituted heteroalkyl, aryl or substituted aryl, or heteroaryl or substituted heteroaryl; or an enantiomer, diastereomer, tautomer, or pharmaceutically acceptable salt or solvate thereof. each of R 1, R 2, and R 3 is independently hydrogen, alkyl or substituted alkyl, alkoxy or substituted alkoxy, heteroalkyl or substituted heteroalkyl, or heteroaryl or substituted heteroaryl; and Z is alkyl or substituted alkyl, alkoxy or substituted alkoxy, heteroalkyl or substituted heteroalkyl, aryl or substituted aryl, or heteroaryl or substituted heteroaryl; or an enantiomer, diastereomer, tautomer, or pharmaceutically acceptable salt or solvate thereof.
An airfoil comprising: a supply passage to provide a coolant; an airfoil section including walls defining an internal cavity; a baffle seated in the internal cavity such that there is a gap between the baffle and at least one of the walls, the baffle including a baffle wall having cooling holes and a baffle edge adjacent the supply passage, the baffle wall defining an interior baffle region; and a seal proximate the baffle edge, the seal sealing off the gap such that the coolant that exits the supply passage will be directed to flow into the interior baffle region, characterised in that: the seal includes a lip having a first seal surface and the at least one of the walls includes a second seal surface abutting the first seal surface of the lip, wherein the lip is on the baffle and is a flared portion at the baffle edge, the lip including a spring biasing the first seal surface and the second seal surface together, and wherein the spring 80a is a leg of the flared portion 80 that deforms within its elastic deformation region to maintain a biasing force. a supply passage to provide a coolant; an airfoil section including walls defining an internal cavity; a baffle seated in the internal cavity such that there is a gap between the baffle and at least one of the walls, the baffle including a baffle wall having cooling holes and a baffle edge adjacent the supply passage, the baffle wall defining an interior baffle region; and a seal proximate the baffle edge, the seal sealing off the gap such that the coolant that exits the supply passage will be directed to flow into the interior baffle region, characterised in that: the seal includes a lip having a first seal surface and the at least one of the walls includes a second seal surface abutting the first seal surface of the lip, wherein the lip is on the baffle and is a flared portion at the baffle edge, the lip including a spring biasing the first seal surface and the second seal surface together, and wherein the spring 80a is a leg of the flared portion 80 that deforms within its elastic deformation region to maintain a biasing force.
The keratinocyte growth factor (KGF/FGF7), orthologs and fragments thereof for use in the treatment of conditions selected from vaginal atrophy and/or vaginal atrophy related dysuria, and/or vaginal atrophy related pain and/or vaginal drying wherein such conditions are induced by a chemotherapy treatment wherein said orthologs and fragments thereof possess the same therapeutic properties of the keratinocyte growth factor and wherein the chemotherapy is an anti-cancer compound belonging to the family of selective estrogen receptor inhibitors.
Method to control a hybrid powertrain, in order to achieve a shift from a low range position to a high range position, wherein the hybrid powertrain 3 comprises an internal combustion engine; a gearbox with an input shaft and an output shaft; a range gearbox connected with the output shaft, a first planetary gear, connected to the input shaft; a second planetary gear, connected to the first planetary gear; a first electrical machine, connected to the first planetary gear; a second electrical machine, connected to the second planetary gear; at least one gear pair (60, 72), connected with the first planetary gear and the output shaft; and at least one gear pair (66, 78), connected with the second planetary gear and the output shaft, wherein the internal combustion engine is connected with the first planetary gear via the input shaft, the method comprising the steps: a) engaging a gear by way of connecting two rotatable components (22, 26, 50) in the first planetary gear; b) connecting the at least one gear pair (66, 78), connected with the second planetary gear (12 and the output shaft; c) connecting a sixth gear pair (G5, 125), arranged between a countershaft and the range gearbox, with the countershaft, so that the countershaft is connected with the output shaft via the range gearbox; d) synchronising the rotational speed between two rotatable components (118, 114) in the range gearbox by means of a synchronisation device; e) connecting the rotatable components (118, 114) in the range gearbox by means of a displaceable third coupling device; and f) engaging a gear by way of connecting two rotatable components (28, 32, 51) in the second planetary gear. a) engaging a gear by way of connecting two rotatable components (22, 26, 50) in the first planetary gear; b) connecting the at least one gear pair (66, 78), connected with the second planetary gear (12 and the output shaft; c) connecting a sixth gear pair (G5, 125), arranged between a countershaft and the range gearbox, with the countershaft, so that the countershaft is connected with the output shaft via the range gearbox; d) synchronising the rotational speed between two rotatable components (118, 114) in the range gearbox by means of a synchronisation device; e) connecting the rotatable components (118, 114) in the range gearbox by means of a displaceable third coupling device; and f) engaging a gear by way of connecting two rotatable components (28, 32, 51) in the second planetary gear.
Apparatus for handling sheet-like media, in particular notes of value, having a transport unit (24, 26, 248, 302, 304) for transporting the sheet-like media, a sensor unit for determining at least one feature of a respective sheet-like medium, a control unit which, on the basis of the feature determined by means of the sensor unit, classifies the sheet-like media as permissible sheet-like media and sheet-like media to be dispensed again, and a diverter which is arranged downstream of the sensor unit and is connected to the sensor unit via a first transport path, wherein the control unit controls the diverter in such a manner that the latter supplies a sheet-like medium classified as a permissible sheet-like medium to a first temporary store for temporarily storing sheet-like media classified as permissible sheet-like media, and in that the diverter supplies a sheet-like medium classified as a sheet-like medium to be dispensed again to a second temporary store for temporarily storing sheet-like media classified as sheet-like media to be dispensed again, characterized in that the second temporary store has at least one circulating belt guided via transport elements and a plurality of rollers and/or guiding elements, wherein the sheet-like media classified as sheet-like media be dispensed again are accommodated in the second temporary store between the belt and the rollers and/or guiding elements and are transported together with the belt in a circulating direction, wherein the sheet-like media temporarily stored in the second temporary store can be directed by a further diverter in such a manner that they are transported in a circulating manner in the circulating direction inside the temporary store.
A resin composition containing an epoxy compound A having a structure of the general formula below and having an epoxy equivalent in the range of from 500 to 10,000 g/eq, and an epoxy compound B having an epoxy equivalent in the range of from 100 to 300 g/eq: wherein, in the formula, each Ar independently represents a structure having an aromatic ring being unsubstituted or having a substituent, each of R 1 and R 2 independently represents a hydrogen atom or an alkyl group having 1 or 2 carbon atoms, each of R 3 to R 8 independently represents a hydroxyl group, a glycidyl ether group and/or a 2-methylglycidyl ether group, wherein at least one of R 3 to R 8 is a glycidyl ether group or a 2-methylglycidyl ether group, each of R 9 to R 12 independently represents a hydrogen atom or a methyl group, n is an integer of 11 to 16, and m, p 1, p 2, and q are an average of the number of repeating units, and m is 0.5 to 25, each of p 1 and P 2 is independently 0 to 5, and q represents 0.5 to 5, wherein the individual repeating units present in the repeating units of the structure are the same or different. wherein, in the formula, each Ar independently represents a structure having an aromatic ring being unsubstituted or having a substituent, each of R 1 and R 2 independently represents a hydrogen atom or an alkyl group having 1 or 2 carbon atoms, each of R 3 to R 8 independently represents a hydroxyl group, a glycidyl ether group and/or a 2-methylglycidyl ether group, wherein at least one of R 3 to R 8 is a glycidyl ether group or a 2-methylglycidyl ether group, each of R 9 to R 12 independently represents a hydrogen atom or a methyl group, n is an integer of 11 to 16, and m, p 1, p 2, and q are an average of the number of repeating units, and m is 0.5 to 25, each of p 1 and P 2 is independently 0 to 5, and q represents 0.5 to 5, wherein the individual repeating units present in the repeating units of the structure are the same or different.
Module comprising a receiving element, in particular in the form of a bearing frame or a covering hood, for arrangement on a cylinder head of an internal combustion engine, and comprising at least one camshaft which is rotatably mounted in the receiving element and which, for holding a camshaft wheel, projects out of an end side of the receiving element, and wherein the module is prefabricated for direct mounting on the cylinder head, characterized in that, for the prefabrication process, the camshaft is locked against rotation by an externally accessible securing part in an angular position which is correct for acting on the valves, wherein the securing part engages through a first aperture in the camshaft wheel and is arranged in positive connection, against rotation, with a receptacle provided in the receiving element, wherein the first aperture is formed as a cylindrical bore which is penetrated by a cylindrical pin, which has a complementary form, of the securing part, wherein the camshaft wheel is a toothed wheel or a belt pulley in whose surface is the first aperture in the form of a bore to be engaged through by a pin provided on the securing part, wherein a sliding fit is provided between the pin and bore and wherein the pin reaches through the bore into the receptacle, which is formed as a securing bore, in the receiving element, and wherein a second aperture is provided in the camshaft wheel for holding the securing part, wherein the securing part is equipped with a corresponding holding means which is in engagement with the second aperture and axially secures the pin, and wherein, after mounting the module on the cylinder head, the securing part can be removed from the locking position.
A printer for digitally printing on 3-dimensional objects with at least one inkjet print head and one rotary table for accommodating the 3-dimensional object, wherein the rotary table is designed for positioning the object in front of the inkjet print head and for rotating the object about its own axis in order to guide the surface of the 3-dimensional object to be printed past the inkjet print head for digital printing, wherein the printer features at least one printing unit with a stamp for separately printing a sign or a logo on the 3-dimensional object by means of a stamp-printing process, wherein the printer is realized in the form of a carousel machine with multiple printing stations, which are arranged on the outer circumferential edge of a machine wheel in a predefined radiant measure and respectively feature at least one inkjet print head and one rotary table for accommodating the 3-dimensional objects in order to digitally print on the 3-dimensional objects, and wherein the machine wheel with the printing stations respectively rotates with a predefined circumferential speed while printing on the 3-dimensional objects, characterized in that the printing unit features a mechanical adjusting unit that is designed for pressing the stamp on the 3-dimensional object in response to a trigger signal, wherein the printing unit features multiple stamps that are arranged on a rotatable wheel, wherein the rotatable wheel is arranged and designed for rotating past the 3-dimensional objects to be printed in the printer such that the stamps contact the surface of the 3-dimensional objects to be printed, and wherein the stamps are arranged on the rotatable wheel of the printing unit and the surfaces to be printed of the 3-dimensional objects accommodated in the printing stations of the carousel machine are arranged on the machine wheel with the same radiant measure (12, 13) and move with the same circumferential speed such that the successively arranged stamps on the rotating wheel print on the 3-dimensional objects, which are respectively arranged in successive printing stations on the circumferential edge, by means of a stamp-printing process.
A δ-Protein Kinase C (δPKC)-selective modulatory peptide consisting of 6 or 7 amino acids comprising the amino acid sequence of SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:6, SEQ ID NO:7, SEQ ID NO:8, SEQ ID NO:9 or SEQ ID NO:10.
A linear actuator system comprising a linear actuator with a housing, an electric motor with a transmission, a spindle unit, an activation element in connection with the spindle unit and wherein the electric motor, via the transmission, drives the spindle unit, by means of which the activation element moves back and forth depending on the direction of rotation of the electric motor, and an outer tube, which protrudes from a side of the housing at a front end thereof, and comprising a control box with a guide, and wherein the control box is arranged in the angle between the housing of the linear actuator and the outer tube, and a mounting bracket, and wherein the control box with the mounting bracket is secured to the outer tube of the linear actuator, and wherein the mounting bracket comprises a tubular portion that can be slid over the outer tube, and that the mounting bracket and the control box have interacting fastening means for fastening the control box to the mounting bracket, characterized in that the tubular portion of the mounting bracket has an axially extending slit, and that the part of the interacting fastening means between the mounting bracket and the control box is formed on both sides of the slit, and in that the interacting fastening means are designed such that when the control box is secured to the mounting bracket, the slit contracts such that the tubular portion of the mounting bracket tightens around the outer tube on the linear actuator.
A method for the preparation and/or purification of a salt composition comprising at least two different borate anions, the method comprising the steps: (a) providing at least two different borate anions, optionally in a predetermined molar ratio, (b) dissolving or mixing and dissolving the anions in isopropanol; (c) drying the solution of step (b) to obtain a solid salt composition comprising the at least two different borate anions, optionally in the predetermined molar ratio, wherein the at least two different borate anions are selected from the group consisting of: (i) B n H n 2-, wherein n is an integer from 4 to 12, optionally 10 or 12; (ii) B n H n+3 -, wherein n is an integer from 1 to 11, optionally BH 4 - and B 11 H 14 -; (iii) B n H n+5 -, wherein n is an integer from 3 to 10, optionally B 3 H 8 -; (iv) B n H (n-y) X y 2-, wherein X is selected from F, CI, Br and I, n is an integer from 4 to 12, and y is an integer from 1 to n; (v) CB n H n+1 -, wherein n is an integer from 3 to 11, optionally 9 or 11; and (vi) SnB n H n+1 -, wherein n is an integer from 3 to 11, optionally 9 or 11. (a) providing at least two different borate anions, optionally in a predetermined molar ratio, (b) dissolving or mixing and dissolving the anions in isopropanol; (c) drying the solution of step (b) to obtain a solid salt composition comprising the at least two different borate anions, optionally in the predetermined molar ratio, (i) B n H n 2-, wherein n is an integer from 4 to 12, optionally 10 or 12; (ii) B n H n+3 -, wherein n is an integer from 1 to 11, optionally BH 4 - and B 11 H 14 -; (iii) B n H n+5 -, wherein n is an integer from 3 to 10, optionally B 3 H 8 -; (iv) B n H (n-y) X y 2-, wherein X is selected from F, CI, Br and I, n is an integer from 4 to 12, and y is an integer from 1 to n; (v) CB n H n+1 -, wherein n is an integer from 3 to 11, optionally 9 or 11; and (vi) SnB n H n+1 -, wherein n is an integer from 3 to 11, optionally 9 or 11.
An absorbent article for absorbing menstrual blood, having a functional substance, wherein the functional substance has a function of inhibiting a factor that acts on blood coagulation, the functional substance is an enzyme having fibrin degradation ability, and the enzyme is a serine protease. the functional substance has a function of inhibiting a factor that acts on blood coagulation, the functional substance is an enzyme having fibrin degradation ability, and the enzyme is a serine protease.
A weight training apparatus reconfigurable between an unfurled open configuration and a rolled or folded compact configuration, characterised in that the apparatus comprises a plurality of pockets configured to removably receive and retain a flowable weighted material to increase the weight of the apparatus, the pockets being movable relative to each other during reconfiguration and arranged to enable the apparatus to be reconfigured to the compact configuration in both a filled condition in which the pockets contain the flowable weighted material and an unfilled condition, wherein the pockets each comprise a sealable opening that is accessible when the apparatus is in the unfurled open configuration to receive and retain flowable material and closure means for closing the pockets and sealing the flowable material within the pockets, and the pockets are arranged such that they are enclosed within the apparatus when the apparatus is in the compact configuration.
A 3D bio-printing platform for supplying nutrition, comprising a rotary rod and a nutrition supply system, wherein at least one end of the rotary rod is configured to be connected to a motor such that the motor is capable of driving rotation of the rotary rod and the rotary rod is arranged horizontally, wherein the rotary rod comprises: a hollow structure for passing a nutrition solution during a 3D bio-printing process, and at least one hole in a surface of the hollow structure for exuding a portion of the nutrition solution, wherein during a 3D bio-printing process, the nutrition supply system delivering a nutrition solution to the rotary rod, such that the nutrition solution passing through the hollow structure of the rotary rod and a portion of the nutrition solution exuding via at least one hole in a surface of the rotary rod. a hollow structure for passing a nutrition solution during a 3D bio-printing process, and at least one hole in a surface of the hollow structure for exuding a portion of the nutrition solution, wherein during a 3D bio-printing process, the nutrition supply system delivering a nutrition solution to the rotary rod, such that the nutrition solution passing through the hollow structure of the rotary rod and a portion of the nutrition solution exuding via at least one hole in a surface of the rotary rod.