mhurhangee/ep-ind-claims huggingface dataset:
Use of a plastic pallet, • with a deck that forms the upperside of the plastic pallet, • where the deck incorporates surface elements that are welded onto its upperside and form a slip-resistant surface layer of the deck, • where the surface elements are made from a co-extruded sheet material, incorporate a slip-resistant coating on their upperside and on their underside are made from a material that is welded to a base body of the plastic pallet, • having feet that extend downwards from the deck • and having runners each of which connects the undersides of a number of feet, • where the runners are designed hollow and are stiffened by means of stiffening ribs to prevent flexing, • and the deck incorporates hollow spaces in which stiffening strips are disposed, • which strips extend the length and breadth of the plastic pallet to stiffen it, • and where the hollow spaces are closed at the top by the co-extruded surface elements, • where the undersides of the runners are unbroken, • where each runner incorporates on its underside a welded-on base plate that extends the full length of the runner and is designed to be slip-resistant on its underside. in mixed operation together with wooden pallets in a conveyor, handling and storage system that has been adapted for the use with wooden pallets. • with a deck that forms the upperside of the plastic pallet, • where the deck incorporates surface elements that are welded onto its upperside and form a slip-resistant surface layer of the deck, • where the surface elements are made from a co-extruded sheet material, incorporate a slip-resistant coating on their upperside and on their underside are made from a material that is welded to a base body of the plastic pallet, • having feet that extend downwards from the deck • and having runners each of which connects the undersides of a number of feet, • where the runners are designed hollow and are stiffened by means of stiffening ribs to prevent flexing, • and the deck incorporates hollow spaces in which stiffening strips are disposed, • which strips extend the length and breadth of the plastic pallet to stiffen it, • and where the hollow spaces are closed at the top by the co-extruded surface elements, • where the undersides of the runners are unbroken, • where each runner incorporates on its underside a welded-on base plate that extends the full length of the runner and is designed to be slip-resistant on its underside.
A pharmaceutical composition containing at least one FGF-21 (fibroblast growth factor 21) compound and at least one GLP-1 R (glucagon-like peptide-1 receptor) agonist for use in treating diabetes, wherein the pharmaceutical composition further comprises an acceptable pharmaceutical carrier, diluent or excipient selected from the group consisting of sterile water, saline containing about 0.9% mg/ml benzyl alcohol, Hank's solution, Ringer's-lactate, lactose, dextrose, sucrose, trehalose, sorbitol, and mannitol.
A switch unit comprising: an upper case on which operation portions (2, 3, 4, 5, 6, 7) are mounted; a circuit board on which switches of which contact points are switched through the operation of the operation portions (2, 3, 4, 5, 6, 7) are mounted; and a lower case that is fitted to the upper case so that side surfaces of the lower case are surrounded by the upper case, the circuit board being accommodated between the upper case and the lower case, characterized in that draining portions are formed integrally with longitudinal side walls forming longitudinal side surfaces of the upper case so as to protrude downward and each of the draining portions has two inclined sides (24, 25) at front and rear sides in a direction along a longitudinal direction of the upper case so that the distance between the two inclined sides (24, 25) on the longitudinal side wall is gradually reduced toward the lower side from the upper side. an upper case on which operation portions (2, 3, 4, 5, 6, 7) are mounted; a circuit board on which switches of which contact points are switched through the operation of the operation portions (2, 3, 4, 5, 6, 7) are mounted; and a lower case that is fitted to the upper case so that side surfaces of the lower case are surrounded by the upper case, the circuit board being accommodated between the upper case and the lower case, characterized in that draining portions are formed integrally with longitudinal side walls forming longitudinal side surfaces of the upper case so as to protrude downward and each of the draining portions has two inclined sides (24, 25) at front and rear sides in a direction along a longitudinal direction of the upper case so that the distance between the two inclined sides (24, 25) on the longitudinal side wall is gradually reduced toward the lower side from the upper side.
A composition comprising pseudotyped lentiviral vector particles comprising (a) a Vpx protein or a Vpr protein that retains SAMHD1-inhibiting activity, (b) a lentiviral vector genome comprising an expressible sequence of interest, and (c) an alphavirus envelope glycoprotein that preferentially binds dendritic cells expressing DC-SIGN, wherein said lentiviral vector particles are produced from a virus packaging cell cultured in a culture medium comprising a mannosidase inhibitor and said lentiviral vector particles are more highly mannosylated compared to a control composition of the same pseudotyped lentiviral vector particles prepared in the absence of a mannosidase inhibitor; wherein at least 80%, at least 90%, at least 95%, at least 99%, or 100% of N-linked glycans on the viral envelope glycoproteins comprise at least a Man 5, Man 6, Man 7, Man 8 and/or Man 9 structure measured by mass spectrometry. (a) a Vpx protein or a Vpr protein that retains SAMHD1-inhibiting activity, (b) a lentiviral vector genome comprising an expressible sequence of interest, and (c) an alphavirus envelope glycoprotein that preferentially binds dendritic cells expressing DC-SIGN, wherein said lentiviral vector particles are produced from a virus packaging cell cultured in a culture medium comprising a mannosidase inhibitor and said lentiviral vector particles are more highly mannosylated compared to a control composition of the same pseudotyped lentiviral vector particles prepared in the absence of a mannosidase inhibitor;
A coating apparatus (600, 700) comprising: a coating application unit comprising: a fluid applicator; a first rotation mechanism and a second rotation mechanism; and a controller, wherein the controller causes the first rotation mechanism and the second rotation mechanism to rotate a medical device at substantially the same speed, wherein the speed is greater than 500 rotations per minute; characterised in that, the fluid applicator comprises a contact fluid applicator; and in that, the fluid applicator comprises a U-channel having a radius of curvature away from a lateral center point, the fluid applicator comprising a fluid orifice, wherein the fluid orifice is disposed on the fluid applicator at a point away from the lateral center point of the fluid applicator. a coating application unit comprising: a fluid applicator; a first rotation mechanism and a second rotation mechanism; and a controller, wherein the controller causes the first rotation mechanism and the second rotation mechanism to rotate a medical device at substantially the same speed, wherein the speed is greater than 500 rotations per minute; a fluid applicator; a first rotation mechanism and a second rotation mechanism; and a controller, wherein the controller causes the first rotation mechanism and the second rotation mechanism to rotate a medical device at substantially the same speed, wherein the speed is greater than 500 rotations per minute; characterised in that, the fluid applicator comprises a contact fluid applicator; and in that, the fluid applicator comprises a U-channel having a radius of curvature away from a lateral center point, the fluid applicator comprising a fluid orifice, wherein the fluid orifice is disposed on the fluid applicator at a point away from the lateral center point of the fluid applicator.
A device for the separation of immune cells by interactions of receptors of said immune cells with ligands wherein the ligands are immobilized in a concentration gradient on a functionalized surface of the device and the device is adapted to flow the immune cells across the functionalized surface, wherein the concentration gradient of the ligands increases along a direction of flow of the immune cells across the functionalized surface.
Tubular heat exchanger comprising a casing tube and at least one inner tube for treating liquid food products, particularly low-viscosity products, such as juices or milk, also with a product counter to product flow guidance, comprising at least one thermal-expansion compensating device for the casing and/or the inner tube (1, 3), with the compensating device having disposed therein at least one surface which can be contacted by the product to be treated wherein the surface which is contacted by the product is provided on at least one bellows integrated into the casing and/or inner tube (1, 3), the surface which can be contacted by the product being provided with a plurality of wide foldings (F1, F) which extend around the tube axis and are of rounded cross-section, characterized in that a plurality of relatively wide foldings which are axially successive with interspaces and substantially equal are provided inwards or outwards and are formed on the surface which can be contacted by the product with the ratio B: T between an axial width and a radial depth of about 1 or more, that narrower foldings (F1') are provided in the interspaces, the narrower foldings (F1') being configured with a ratio of B1: T of less than 1, and that each folding (F, F1) is formed in an axial section of the inner tube or casing tube (3, 1) of circle arc sections continuously passed into one another, the circular-arc sections having a radius of curvature (R1, R2, R2') corresponding to about half the depth and/or the width.
Length-adjustable connecting rod for a reciprocating-piston machine, in particular an internal combustion engine, having at least one first rod part with a small connecting rod eye and at least one second rod part with a large connecting rod eye, which two rod parts are telescopically displaceable towards and/or into one another in the direction of a longitudinal axis of the connecting rod, wherein the second rod part has a guide cylinder and the first rod part is fixedly connected to a piston element which is longitudinally displaceable in the guide cylinder, wherein on a first side of the piston element between the second rod part and the piston element a first high-pressure chamber is defined and on a second side of the piston element a second high-pressure chamber is defined, wherein each high-pressure chamber (10, 12) is flow-connected to at least one oil channel (15, 16), and wherein at least one sealing element (22, 24) is provided for sealing at least one high-pressure chamber (10, 12), characterised in that the piston element is non-positively connected to the first rod part in a press fit region via an interference fit.
A multikinase inhibitor for use in a method of preventing and/or treating fibrosis associated with an eye-related disease, eye-related disorder or eye-related surgical procedure in a subject in need thereof, wherein the multikinase inhibitor is nintedanib or a salt thereof, lenvatinib or a salt thereof, or a combination thereof.
A pharmaceutical composition, the composition comprising a pharmaceutical carrier and an organic arsenic compound having the following structure or a pharmaceutically acceptable salt thereof, wherein the pharmaceutical composition has a pH of 5 to 7.
Electrosurgical pencil adapted to receive an electrode controllable by an electrical signal for performing surgical operations, comprising: a housing, a circuit, switching means (3, 71) adapted to be activated from outside the housing for closing the circuit, wherein the housing comprises receiving means for receiving the electrode, wherein the circuit is a flexible circuit, characterized in that the flexible circuit is positioned such that it is in direct contact with the electrode, when the electrode is positioned in the receiving means. a housing, a circuit, switching means (3, 71) adapted to be activated from outside the housing for closing the circuit, wherein the housing comprises receiving means for receiving the electrode, wherein the circuit is a flexible circuit, characterized in that the flexible circuit is positioned such that it is in direct contact with the electrode, when the electrode is positioned in the receiving means.
A composition for use in a method of treating ocular inflammation in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of the composition, wherein the composition comprises: a chemerin fragment having the sequence of YFPGQFAFS (SEQ ID NO.: 2) or a chemerin analog having the sequence of Y*FLPS*QFA*-Tic-S (SEQ ID NO.: 3), * denoting D amino acids, wherein Tic represents 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; a lipid entity linked to the chemerin fragment or chemerin analog; and optionally a linker connecting the lipid entity to the chemerin fragment or chemerin analog. a chemerin fragment having the sequence of YFPGQFAFS (SEQ ID NO.: 2) or a chemerin analog having the sequence of Y*FLPS*QFA*-Tic-S (SEQ ID NO.: 3), * denoting D amino acids, wherein Tic represents 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; a lipid entity linked to the chemerin fragment or chemerin analog; and optionally a linker connecting the lipid entity to the chemerin fragment or chemerin analog.
A drive device for an electric vehicle, comprising: an electric motor, a speed reduction unit including an input shaft driven by output of the electric motor; a hub unit rotationally driven by an output member of the speed reduction unit; and a housing accommodating the electric motor and the speed reduction unit, wherein a rear end portion of an accommodation section accommodating the electric motor and the speed reduction unit of the housing is opened, the opening portion is closed by a rear cover, and power supply means for the electric motor is provided in the housing, the drive device for an electric vehicle being configured such that the power supply means is made up of a power supply terminal box comprising: an accommodation recessed portion; a power supply terminal provided inside the accommodation recessed portion; a communication hole in communication with the accommodation recessed portion and an interior of the housing; and a cover member of the accommodation recessed portion, and a lead wire of the electric motor is connected to the power supply terminal through the communication hole, and an insertion hole for a connection terminal of a power supply cable is provided in the power supply terminal box characterized in that the electric motor is disposed on an outer radial side of the speed reduction unit in the housing, and the accommodation recessed portion is provided in a rear end surface of the housing.
A slide door structure comprising: a slide door provided so as to be movable with respect to a vehicle body; and a wire harness routed between the vehicle body and the slide door by allowing an electric wire bundle to pass through a bendable exterior member, wherein the wire harness is connected to the slide door by a fixture including an outer member attached to the slide door and an inner member provided on the wire harness and supported by the outer member so as to be rotatable about an axis in an upperlower direction as a center, wherein in the fixture, the inner member is supported by the outer member so as to be slidable in a direction perpendicular to the axis, wherein a shaft portion is formed in the inner member, wherein a support hole formed of a long hole is formed in the outer member, and wherein the shaft portion is inserted into the support hole and the inner member is rotatably and slidably supported by the outer member. a slide door provided so as to be movable with respect to a vehicle body; and a wire harness routed between the vehicle body and the slide door by allowing an electric wire bundle to pass through a bendable exterior member, wherein the wire harness is connected to the slide door by a fixture including an outer member attached to the slide door and an inner member provided on the wire harness and supported by the outer member so as to be rotatable about an axis in an upperlower direction as a center, wherein in the fixture, the inner member is supported by the outer member so as to be slidable in a direction perpendicular to the axis, wherein a shaft portion is formed in the inner member, wherein a support hole formed of a long hole is formed in the outer member, and wherein the shaft portion is inserted into the support hole and the inner member is rotatably and slidably supported by the outer member.
A method for deploying a calibrated positioning map of an area, the method executed in a processor of a server computing device and comprising: receiving, at a memory of the server computing device, a first set of fingerprint data acquired within the area by a plurality of mobile devices (102a-n) in the area, fingerprint data comprising time-correlated signal information and sensor information at fixed locations within the area; generating, using the processor, a distribution of calibrated data points covering the area, based at least in part on the first set of fingerprint data, each calibrated data point representing a corresponding coordinate location and associated fingerprint data; receiving, at the memory, a second set of fingerprint data acquired by at least one additional mobile device within the area; updating the distribution of calibrated data points obtained using first set of fingerprint data to generate an updated distribution of calibrated data points, based on the second set of fingerprint data; and when the updated distribution exceeds at least one of a predetermined and a dynamically updated threshold density of the calibrated data points, deploying the updated distribution as the calibrated positioning map of the area, the calibrated positioning map comprising the fingerprint data corresponding to multiple locations within the area for navigating a user in the area. receiving, at a memory of the server computing device, a first set of fingerprint data acquired within the area by a plurality of mobile devices (102a-n) in the area, fingerprint data comprising time-correlated signal information and sensor information at fixed locations within the area; generating, using the processor, a distribution of calibrated data points covering the area, based at least in part on the first set of fingerprint data, each calibrated data point representing a corresponding coordinate location and associated fingerprint data; receiving, at the memory, a second set of fingerprint data acquired by at least one additional mobile device within the area; updating the distribution of calibrated data points obtained using first set of fingerprint data to generate an updated distribution of calibrated data points, based on the second set of fingerprint data; and when the updated distribution exceeds at least one of a predetermined and a dynamically updated threshold density of the calibrated data points, deploying the updated distribution as the calibrated positioning map of the area, the calibrated positioning map comprising the fingerprint data corresponding to multiple locations within the area for navigating a user in the area.
A brake pad assembly for use with a brake caliper piston that applies a compressive force to the brake pad assembly, comprising: a fully-formed friction lining providing a wear surface for contacting a brake rotor; and a fully-formed back plate having a first side that is coupled to the friction lining and an opposite second side to receive the compressive force of a caliper piston, characterized by the back plate being made of a carbon fiber reinforced carbonaceous matrix composite, wherein the back plate includes a generally planar support surface to couple to the friction lining that defines an x-y in-plane direction and a majority of the carbon fibers of the back plate are oriented in the x-y in-plane direction to conduct thermal energy produced by the compressive force on the brake pad assembly along the x-y in-plane direction of the back plate and away from the caliper piston, and resulting in a back plate where the thermal conductivity is at least 2 times greater in the x-y in-plane direction of the back plate versus a z through-plane direction of the back plate. a fully-formed friction lining providing a wear surface for contacting a brake rotor; and a fully-formed back plate having a first side that is coupled to the friction lining and an opposite second side to receive the compressive force of a caliper piston, characterized by the back plate being made of a carbon fiber reinforced carbonaceous matrix composite, wherein the back plate includes a generally planar support surface to couple to the friction lining that defines an x-y in-plane direction and a majority of the carbon fibers of the back plate are oriented in the x-y in-plane direction to conduct thermal energy produced by the compressive force on the brake pad assembly along the x-y in-plane direction of the back plate and away from the caliper piston, and resulting in a back plate where the thermal conductivity is at least 2 times greater in the x-y in-plane direction of the back plate versus a z through-plane direction of the back plate.
Molding station for manufacturing polyurethane semi worked items, comprising a mold holder, a mold for manufacturing polyurethane semi worked items, and a nozzle for dispensing polyurethane in liquid state, wherein: - the mold holder comprises a rest surface for holding the mold, means for rotating the rest surface around a pitch axis y and means for rotating the rest surface around a roll axis x; - the mold is constrained to the rest surface of the mold holder; - the mold comprises a bottom wall and side walls, so as to define a cavity, and a cover suitable for closing the cavity; and wherein - the dispensing nozzle comprises moving means and dispensing control means, controlled electronically, and is suitable for dispensing polyurethane in liquid state in the mold. - the mold holder comprises a rest surface for holding the mold, means for rotating the rest surface around a pitch axis y and means for rotating the rest surface around a roll axis x; - the mold is constrained to the rest surface of the mold holder; - the mold comprises a bottom wall and side walls, so as to define a cavity, and a cover suitable for closing the cavity; and wherein - the dispensing nozzle comprises moving means and dispensing control means, controlled electronically, and is suitable for dispensing polyurethane in liquid state in the mold.