A system comprising at least one processor (402, 404), a sensor cartridge, means for outputting the results of the determination and a non-transitory computer-readable medium that stores instructions that, when executed by the at least one processor cause the system to determine a level of hemolysis of a sample of whole blood, by: receiving a first intercellular concentration, i.e. a concentration in the blood plasma, of a first compound in the whole blood sample, the first intercellular concentration having been obtained from a first sensor disposed on a sensor cartridge, the first sensor being specific to the first compound, an intracellular concentration, i.e. a concentration in the red blood cells, of the first compound being higher than the intercellular concentration in the whole blood sample; the system being characterized by receiving a second intercellular concentration of a second compound in the whole blood sample, the second concentration having been obtained from a second sensor on the sensor cartridge that is specific to the second compound, an intracellular concentration of the second compound being higher than the intercellular in the whole blood sample; receiving a third intercellular concentration of a third analyte, the third concentration having been obtained from a third sensor on the sensor cartridge that is specific to the third compound, the third analyte being a compound with an intracellular concentration lower than the intercellular concentration in the whole blood sample; computing a first ratio of the first concentration to the third concentration; computing a second ratio of the second concentration to the third concentration, and determining the degree of hemolyzation of the whole blood sample based on the first ratio and the second ratio; and outputting the determination to a medical professional wherein the first compound is potassium ions ('K + '), and the first concentration is obtained from a K + ion selective electrode on the sensor cartridge; wherein the second compound is magnesium ions (Mg++) and the second concentration is obtained from a Mg++ ion selective electrode on the sensor cartridge; and wherein the third compound is sodium ions (Na+) or calcium ions (Ca++) and the third concentration is obtained from corresponding Na+ or Ca++ ion selective electrode on the sensor cartridge. receiving a first intercellular concentration, i.e. a concentration in the blood plasma, of a first compound in the whole blood sample, the first intercellular concentration having been obtained from a first sensor disposed on a sensor cartridge, the first sensor being specific to the first compound, an intracellular concentration, i.e. a concentration in the red blood cells, of the first compound being higher than the intercellular concentration in the whole blood sample; the system being characterized by receiving a second intercellular concentration of a second compound in the whole blood sample, the second concentration having been obtained from a second sensor on the sensor cartridge that is specific to the second compound, an intracellular concentration of the second compound being higher than the intercellular in the whole blood sample; receiving a third intercellular concentration of a third analyte, the third concentration having been obtained from a third sensor on the sensor cartridge that is specific to the third compound, the third analyte being a compound with an intracellular concentration lower than the intercellular concentration in the whole blood sample; computing a first ratio of the first concentration to the third concentration; computing a second ratio of the second concentration to the third concentration, and determining the degree of hemolyzation of the whole blood sample based on the first ratio and the second ratio; and outputting the determination to a medical professional wherein the first compound is potassium ions ('K + '), and the first concentration is obtained from a K + ion selective electrode on the sensor cartridge; wherein the second compound is magnesium ions (Mg++) and the second concentration is obtained from a Mg++ ion selective electrode on the sensor cartridge; and wherein the third compound is sodium ions (Na+) or calcium ions (Ca++) and the third concentration is obtained from corresponding Na+ or Ca++ ion selective electrode on the sensor cartridge.