A guide wire for biological pressure measurement comprising: a tube extending along an axial direction of the guide wire, wherein the tube comprises a circumferential wall and defines a proximal-end opening and a distal-end opening; and a pressure sensor configured for biological pressure measurement, wherein at least a portion of the pressure sensor is mounted within the tube, and wherein the pressure sensor comprises a pressure sensor transducer, the circumferential wall of the tube includes exactly three openings (35, 36, 37) configured for fluid and gas ingress and egress extending radially therethrough: a first elongated opening, a second elongated opening, and a third elongated openings, wherein each of the first, second, and third elongated openings (35, 36, 37) is elongated in the axial direction of the guide wire, wherein a majority of each of the first, second, and third elongated openings (35, 36, 37) is located within a distal half of the tube, the first elongated opening is located at a location opposing the pressure sensor transducer such that the pressure sensor transducer is exposed via the first elongated opening, characterized in that the second elongated opening is located such that, in a cross-sectional view, a bisector (B 2) of the second elongated opening is offset from a bisector (B 1) of the first elongated opening in a first circumferential direction by an angle (θ 1) in a range of 95 to 115 degrees, and the third elongated opening is located such that, in the cross-sectional view, a bisector (B 3) of the third elongated opening is offset from the bisector (B 1) of the first elongated opening in a second circumferential direction by an angle (θ 2) in a range of 95 to 115 degrees, wherein, in the cross-sectional view, a circumferential angle (φ O1) over which the first elongated opening extends is greater than a circumferential angle (φ O2) over which the second elongated opening extends and a circumferential angle (φ O3) over which the third elongated opening extends. a tube extending along an axial direction of the guide wire, wherein the tube comprises a circumferential wall and defines a proximal-end opening and a distal-end opening; and a pressure sensor configured for biological pressure measurement, wherein at least a portion of the pressure sensor is mounted within the tube, and wherein the pressure sensor comprises a pressure sensor transducer, the circumferential wall of the tube includes exactly three openings (35, 36, 37) configured for fluid and gas ingress and egress extending radially therethrough: a first elongated opening, a second elongated opening, and a third elongated openings, wherein each of the first, second, and third elongated openings (35, 36, 37) is elongated in the axial direction of the guide wire, wherein a majority of each of the first, second, and third elongated openings (35, 36, 37) is located within a distal half of the tube, the first elongated opening is located at a location opposing the pressure sensor transducer such that the pressure sensor transducer is exposed via the first elongated opening, characterized in that the second elongated opening is located such that, in a cross-sectional view, a bisector (B 2) of the second elongated opening is offset from a bisector (B 1) of the first elongated opening in a first circumferential direction by an angle (θ 1) in a range of 95 to 115 degrees, and the third elongated opening is located such that, in the cross-sectional view, a bisector (B 3) of the third elongated opening is offset from the bisector (B 1) of the first elongated opening in a second circumferential direction by an angle (θ 2) in a range of 95 to 115 degrees, wherein, in the cross-sectional view, a circumferential angle (φ O1) over which the first elongated opening extends is greater than a circumferential angle (φ O2) over which the second elongated opening extends and a circumferential angle (φ O3) over which the third elongated opening extends. wherein each of the first, second, and third elongated openings (35, 36, 37) is elongated in the axial direction of the guide wire, wherein a majority of each of the first, second, and third elongated openings (35, 36, 37) is located within a distal half of the tube, the first elongated opening is located at a location opposing the pressure sensor transducer such that the pressure sensor transducer is exposed via the first elongated opening, characterized in that the second elongated opening is located such that, in a cross-sectional view, a bisector (B 2) of the second elongated opening is offset from a bisector (B 1) of the first elongated opening in a first circumferential direction by an angle (θ 1) in a range of 95 to 115 degrees, and the third elongated opening is located such that, in the cross-sectional view, a bisector (B 3) of the third elongated opening is offset from the bisector (B 1) of the first elongated opening in a second circumferential direction by an angle (θ 2) in a range of 95 to 115 degrees, wherein, in the cross-sectional view, a circumferential angle (φ O1) over which the first elongated opening extends is greater than a circumferential angle (φ O2) over which the second elongated opening extends and a circumferential angle (φ O3) over which the third elongated opening extends.