mhurhangee/ep-ind-claims huggingface dataset:
A method for identifying functionally interacting amino acid residues in a protein of interest, said method comprising: a. obtaining a first library of single mutation variants of said protein of interest by single-site saturation mutagenesis, wherein said each variant contains an amino acid substitution at a single residue position, and at least 70% of each possible amino acid substitution at each residue position of said protein of interest is represented in said first library; b. identifying a first subpopulation of variants from the first library, wherein said first subpopulation comprises a population enriched in single amino acid substitution variants, each of which decreases the activity of said protein of interest compared to wild-type levels; c. introducing at least five mutations at different residue positions from said first subpopulation singly in to each variant of the first library to obtain a second library of variants having two or one amino acid substitution in said protein of interest; d. identifying a second subpopulation from said second library, comprising variants, each of which has two amino acid substitutions in said protein of interest; e. identifying a third subpopulation, which is a subset of the said second subpopulation of said second library, wherein in each variant of said third subpopulation, the mutation as identified from each variant of said first library suppresses the altered activity of the variant of the first subpopulation, wherein the two substituted amino acids in each variant of the said third subpopulation are indicative that the two amino acids at corresponding positions in wild-type said protein of interest are functionally interacting. a. obtaining a first library of single mutation variants of said protein of interest by single-site saturation mutagenesis, wherein said each variant contains an amino acid substitution at a single residue position, and at least 70% of each possible amino acid substitution at each residue position of said protein of interest is represented in said first library; b. identifying a first subpopulation of variants from the first library, wherein said first subpopulation comprises a population enriched in single amino acid substitution variants, each of which decreases the activity of said protein of interest compared to wild-type levels; c. introducing at least five mutations at different residue positions from said first subpopulation singly in to each variant of the first library to obtain a second library of variants having two or one amino acid substitution in said protein of interest; d. identifying a second subpopulation from said second library, comprising variants, each of which has two amino acid substitutions in said protein of interest; e. identifying a third subpopulation, which is a subset of the said second subpopulation of said second library, wherein in each variant of said third subpopulation, the mutation as identified from each variant of said first library suppresses the altered activity of the variant of the first subpopulation,
A maneuvering drive for a vehicle, comprising a drive roller adapted to be rotationally driven about an axis of rotation by a drive motor and adapted to be pressed against a tread of a tire of the vehicle in a drive position and to be released from the tread in a rest position; the drive roller having a cover surface that can be brought into contact with the tire for transmitting a driving torque of the drive motor to the tire; and the cover surface having a first point provided thereon which, as related to the axis of rotation, is located closer towards the axial center and which has a greater radial distance from the axis of rotation than a second point (P2, P2') which is offset axially outwards relative thereto, further away from the axial center; the cover surface including a first side portion adjacent to a first face side of the drive roller, a second side portion adjacent to a second face side of the drive roller, and a central portion located between the first side portion and the second side portion; the first point being located in the central portion; the second point (P2, P2') being arranged in the first side portion or in the second side portion; the first point having a greater radial distance than all further points (P2, P2') of the cover surface which are located in the first and/or the second side portion (S1, S2), characterized in that the radial distance of the cover surface along the axis of rotation is initially small in the first side portion, then at first increases towards the central portion or in the central portion up to a maximum of the radial distance in the central portion and subsequently decreases again in the central portion or in the second side portion, so that the contact pressure is increased in the middle portion of the tread when the drive roller has been brought into contact with the tire.
A glass composition for glass fiber comprising: SiOz in a range of 52.0% by mass or more and 56.0% by mass or less; B 2 O 3 in a range of 21.0% by mass or more and 24.5% by mass or less; Al 2 O 3 in a range of 9.5% by mass or more and 13.0% by mass or less; MgO in a range of 0% by mass or more and 0.9% by mass or less; CaO in a range of 0.5% by mass or more and 5.5% by mass or less; SrO in a range of 0.5% by mass or more and 6.0% by mass or less; and TiO 2 in a range of 0.1% by mass or more and 3.0% by mass or less; and comprising F 2 and Cl 2 in a range of 0.1% by mass or more and 2.0% by mass or less in total, with respect to the total amount. SiOz in a range of 52.0% by mass or more and 56.0% by mass or less; B 2 O 3 in a range of 21.0% by mass or more and 24.5% by mass or less; Al 2 O 3 in a range of 9.5% by mass or more and 13.0% by mass or less; MgO in a range of 0% by mass or more and 0.9% by mass or less; CaO in a range of 0.5% by mass or more and 5.5% by mass or less; SrO in a range of 0.5% by mass or more and 6.0% by mass or less; and TiO 2 in a range of 0.1% by mass or more and 3.0% by mass or less; and comprising F 2 and Cl 2 in a range of 0.1% by mass or more and 2.0% by mass or less in total, with respect to the total amount.
A device for mobile phone radio frequency test, comprising: a radio frequency test socket, wherein the radio frequency test socket comprises a radio frequency test base; a connection component fixed in the radio frequency test base; a first elastic component and a second elastic component, wherein the first elastic component and the second elastic component are fixed in the radio frequency test base, and connected to the connection component respectively.; a radio frequency test cable, wherein the radio frequency test cable comprises: a radio frequency test plug fixed at an end of the radio frequency test cable; and an insulated push pin which is installed on a side of the radio frequency test plug and is longer than the radio frequency test plug; and a test module, configured to test, through the radio frequency test cable and the radio frequency test socket, a first test apparatus and a second test apparatus respectively, wherein the first test apparatus and the second test apparatus are connected to the first elastic component and the second elastic component in the radio frequency test socket respectively, wherein the test module comprises a first test submodule configured to test the first test apparatus connected to the first elastic component by disconnecting the radio frequency test cable from the second test apparatus through urging the insulated push pin against the second elastic component, and utilizing a connection between the radio frequency test plug and the connection component. a radio frequency test socket, wherein the radio frequency test socket comprises a radio frequency test base; a connection component fixed in the radio frequency test base; a first elastic component and a second elastic component, wherein the first elastic component and the second elastic component are fixed in the radio frequency test base, and connected to the connection component respectively.; a radio frequency test cable, wherein the radio frequency test cable comprises: a radio frequency test plug fixed at an end of the radio frequency test cable; and an insulated push pin which is installed on a side of the radio frequency test plug and is longer than the radio frequency test plug; and a test module, configured to test, through the radio frequency test cable and the radio frequency test socket, a first test apparatus and a second test apparatus respectively, wherein the first test apparatus and the second test apparatus are connected to the first elastic component and the second elastic component in the radio frequency test socket respectively, wherein the test module comprises a first test submodule configured to test the first test apparatus connected to the first elastic component by disconnecting the radio frequency test cable from the second test apparatus through urging the insulated push pin against the second elastic component, and utilizing a connection between the radio frequency test plug and the connection component.
A wood-based composite board products comprising copolymer resin that contains polyflavonoid, amino groups, urea and formaldehyde characterized in that copolymer resin comprises; formaldehyde at a weight ratio of 25-40%, sum of urea, and amino groups at a weight ratio 55-75%, polyflavonoid at a weight ratio 1-12% in solid form. formaldehyde at a weight ratio of 25-40%, sum of urea, and amino groups at a weight ratio 55-75%, polyflavonoid at a weight ratio 1-12% in solid form.
A sprayer that senses the presence or character of a surface to be sprayed, comprising: one or more sensors including at least a UV camera, configured to detect a presence or character of a surface to be sprayed; and a dispenser assembly including one or more components configured to modify at least one spray characteristic of a formulation based on an input from at least one of the one or more sensors indicative of the presence or character of the surface to be sprayed, characterized in that the sprayer comprises a plurality of UV sunscreen lotions, each having a different sun protection factor; the UV camera, an image processor, and a controller configured to measure one or more of brightness, contrast, and intensity of UV on a surface and determine the amount of SPF required by the surface, and to apply the UV sunscreen lotion having the appropriate SPF. one or more sensors including at least a UV camera, configured to detect a presence or character of a surface to be sprayed; and a dispenser assembly including one or more components configured to modify at least one spray characteristic of a formulation based on an input from at least one of the one or more sensors indicative of the presence or character of the surface to be sprayed, characterized in that the sprayer comprises a plurality of UV sunscreen lotions, each having a different sun protection factor; the UV camera, an image processor, and a controller configured to measure one or more of brightness, contrast, and intensity of UV on a surface and determine the amount of SPF required by the surface, and to apply the UV sunscreen lotion having the appropriate SPF.
A synthetic-resin screw cap comprising: a pour-cap main body having an attaching cylinder getting over and fitted on a bottle mouth cylinder and forming a pour spout by being closely fitted, an outer cap which has a cylindrical shape with a top for opening and closing the pour spout, a sealing ring integrally connected to the lower end of an outer cylinder through a plurality of easily breakable pieces, and the sealing ring having a second locking section to be locked from below to a first locking section, wherein a plurality of second pressing slopes is disposed on the upper end of the sealing ring and is closely opposed to a plurality of first pressing slopes disposed on the lower end of the outer cylinder so that the plurality of second pressing slopes would slidably come in contact with the plurality of first pressing slopes from an unscrewing direction characterised by a first locking section being formed around the outer peripheral surface of the attaching cylinder; and the outer cylinder of the outer cap to be fitted on the attaching cylinder in a closed state, wherein the slopes have a tilt angle that is a larger acute angle (b) than the lead angle (a) of the helical ridge of the pour-cap main body constructing the function of screwing the outer cap and the pour-cap main body together. a pour-cap main body having an attaching cylinder getting over and fitted on a bottle mouth cylinder and forming a pour spout by being closely fitted, an outer cap which has a cylindrical shape with a top for opening and closing the pour spout, a sealing ring integrally connected to the lower end of an outer cylinder through a plurality of easily breakable pieces, and the sealing ring having a second locking section to be locked from below to a first locking section, wherein a plurality of second pressing slopes is disposed on the upper end of the sealing ring and is closely opposed to a plurality of first pressing slopes disposed on the lower end of the outer cylinder so that the plurality of second pressing slopes would slidably come in contact with the plurality of first pressing slopes from an unscrewing direction characterised by a first locking section being formed around the outer peripheral surface of the attaching cylinder; and the outer cylinder of the outer cap to be fitted on the attaching cylinder in a closed state, wherein the slopes have a tilt angle that is a larger acute angle (b) than the lead angle (a) of the helical ridge of the pour-cap main body constructing the function of screwing the outer cap and the pour-cap main body together.
A device for locking an object (20; 50) suspended from a cable, the device comprising a cable and a clamp, the cable passing through the clamp by extending along a substantially vertical axis, the clamp comprising: a fixed part (54; 102) connected to the object (20; 50), at least two movable jaws, a first actuator and a second actuator, the two jaws being capable of translationally moving relative to one another in a direction perpendicular to the axis of the cable, the two jaws coming into contact with the cable to immobilise the cable by clamping in a closed position and moving away from the cable in an open position, the fixed part (54; 102) having as many inclined surfaces as jaws, the inclined surfaces being inclined relative to the axis of the cable, so as to upwardly move closer to the axis of the cable, each of the jaws being configured to slide along one of the inclined surfaces, the sliding allowing the jaws to transition from the open position to the closed position, the clamp further comprising elastic elements configured to move the jaws away from the cable, the first actuator being configured to move the jaws upwards, to make them slide along their respective inclined surface and to allow the clamp to close, the second actuator being configured to downwardly pull on the cable relative to the fixed part (54; 102) and to allow the clamp to open.
An enclosure for vertical pulverizer systems comprising: a cylindrical body forming an internal cavity, the cylindrical body being vertically oriented; a cover positioned above the cylindrical body, the cover having a curved non-linear and dome-shaped surface; an inlet channel formed through the cover, the inlet channel in fluid communication with the internal cavity of the cylindrical body; an outlet channel formed through the cover, and adjacent to the inlet channel; a base component positioned within the internal cavity of the cylindrical body, opposite the cover, a journal opening formed through the cylindrical body between the cover and the base component; a journal opening cover coupled to the cylindrical body, the journal opening cover covering the journal opening; characterised in that the base component has, similar to cover, a curved non-linear and dome-shaped surface; wherein the curved surface of the base component is substantially concave in shape; and wherein the curved surface of the base component extends around a perimeter of the base component. a cylindrical body forming an internal cavity, the cylindrical body being vertically oriented; a cover positioned above the cylindrical body, the cover having a curved non-linear and dome-shaped surface; an inlet channel formed through the cover, the inlet channel in fluid communication with the internal cavity of the cylindrical body; an outlet channel formed through the cover, and adjacent to the inlet channel; a base component positioned within the internal cavity of the cylindrical body, opposite the cover, a journal opening formed through the cylindrical body between the cover and the base component; a journal opening cover coupled to the cylindrical body, the journal opening cover covering the journal opening; wherein the curved surface of the base component is substantially concave in shape; and wherein the curved surface of the base component extends around a perimeter of the base component.
A circulator device (200a, 200b, 200c, 200d, 200e), the circulator device (200a, 200b, 200c, 200d, 200e) comprising: two magnet-free circulators (220a, 220b), each of which having a forced time variance; and ports (240a, 240b, 240c, 240d), wherein the two circulators (220a, 220b) are in the circulator device (200a, 200b, 200c, 200d, 200e) arranged to have mutually anti-phase time variance, and wherein each of the two circulators (220a, 220b) is coupled to all of the ports (240a, 240b, 240c, 240d), wherein each of the two circulators (220a, 220b) is modulated by a poly-phase signal with an angular direction of phase progression, and wherein the two circulators (220a, 220b) have same angular direction but 180 degrees out of phase. two magnet-free circulators (220a, 220b), each of which having a forced time variance; and ports (240a, 240b, 240c, 240d), wherein the two circulators (220a, 220b) are in the circulator device (200a, 200b, 200c, 200d, 200e) arranged to have mutually anti-phase time variance, and wherein each of the two circulators (220a, 220b) is coupled to all of the ports (240a, 240b, 240c, 240d), wherein each of the two circulators (220a, 220b) is modulated by a poly-phase signal with an angular direction of phase progression, and wherein the two circulators (220a, 220b) have same angular direction but 180 degrees out of phase.
A system, comprising: one or more fiber optic sensors configured to be disposed within an electrochemical battery, each fiber optic sensor configured to receive input light and to provide output light that varies based on the input light and an amount of free or dissolved gas present within the battery, wherein each fiber optic sensor includes an optical fiber and a gas-specific coating (808, 809)inside the fiber and disposed along the length of the optical fiber or disposed at the end tip of the optical fiber and which changes one or more optical properties in the presence of a specific gas a light source configured to provide the input light to the fiber optic sensors; a detector configured to detect the output light and to generate an electrical detector signal in response to the output light; and battery management circuitry configured to determine a state of the battery based at least in part on the detector signal, and further configured to detect abnormal levels of gas generation based on at least one of a comparison of the detector signal to a threshold value, and a rate of change of the detector signal. one or more fiber optic sensors configured to be disposed within an electrochemical battery, each fiber optic sensor configured to receive input light and to provide output light that varies based on the input light and an amount of free or dissolved gas present within the battery, wherein each fiber optic sensor includes an optical fiber and a gas-specific coating (808, 809)inside the fiber and disposed along the length of the optical fiber or disposed at the end tip of the optical fiber and which changes one or more optical properties in the presence of a specific gas a light source configured to provide the input light to the fiber optic sensors; a detector configured to detect the output light and to generate an electrical detector signal in response to the output light; and battery management circuitry configured to determine a state of the battery based at least in part on the detector signal, and further configured to detect abnormal levels of gas generation based on at least one of a comparison of the detector signal to a threshold value, and a rate of change of the detector signal.
A radio frequency coil device for a magnetic resonance examination system, whereby the RF coil device comprises a first coil and a second coil, the first coil and the second coil are arranged with a common center axis, the first coil and the second coil have rungs, which are arranged non-parallel to the center axis of the RF coil device, the RF coil device is provided integrally with a RF screen device surrounding the first coil and the second coil, the rungs are coupled to the RF screen device, the first coil has a coil structure different from a coil structure of the second coil, and the first coil and the second coil are switchable to be active for different modes of operation.
A device for measuring a magnetic field oriented along a longitudinal axis (ZZ'), the device comprising: - at least four magnetic field sensors (12, 14, 16, 18), + each providing a magnetic field measurement, + distributed in two pairs of sensors (12 and 14, 16 and 18), both pairs not having any common sensor, - first means (24; 124; 224) for subtracting the measurements of both sensors of the first pair, in order to obtain a first magnetic field gradient, - second means (26; 126; 226) for subtracting the measurements of both sensors of the second pair, in order to obtain a second magnetic field gradient, the device comprising along the longitudinal axis (ZZ') a front portion intended to come into proximity to a source (21; 121; 221) of a magnetic field to be measured, the first pair of sensors being closer to the front portion than the second pair of sensors, characterized in that the device further comprises: - means for generating polarization fields for the sensors (12, 14) of the first pair, determined from the second magnetic field gradient provided by the second subtraction means. - at least four magnetic field sensors (12, 14, 16, 18), + each providing a magnetic field measurement, + distributed in two pairs of sensors (12 and 14, 16 and 18), both pairs not having any common sensor, + each providing a magnetic field measurement, + distributed in two pairs of sensors (12 and 14, 16 and 18), both pairs not having any common sensor, - first means (24; 124; 224) for subtracting the measurements of both sensors of the first pair, in order to obtain a first magnetic field gradient, - second means (26; 126; 226) for subtracting the measurements of both sensors of the second pair, in order to obtain a second magnetic field gradient, - means for generating polarization fields for the sensors (12, 14) of the first pair, determined from the second magnetic field gradient provided by the second subtraction means.
A bank-note processing apparatus to which a bank-note stack in a banded state is suppliable, comprising a debanding station for removing the band from the bank-note stack, and an image capturing device by means of which first and second information items applied to the band can be optically captured and digitally stored, characterized in that the image capturing device comprises at least one mirror which is arranged in the bank-note processing apparatus such that those first and second information items applied to the band that lie on different sides of the bank-note stack on the banded bank-note stack are optically capturable by means of the image capturing device simultaneously.