mhurhangee/ep-ind-claims huggingface dataset:
A nucleic acid vector, wherein the nucleic acid encodes: (i) a first endoplasmic reticulum targeting sequence and a first endoplasmic reticulum retention sequence; (ii) a surface expression sequence; (iii) a first peptide sequence that is a counterselection substrate sequence for the enzyme of (vii); (iv) a first epitope tag sequence; (v) a second peptide sequence that is a selection substrate sequence for the enzyme of (vii); (vi) a second epitope tag sequence; (vii) an enzyme, wherein the enzyme is a protease variant or a protein kinase variant; and (viii) a second endoplasmic reticulum targeting sequence and a second endoplasmic reticulum retention sequence; wherein (i), (ii), (iii), (iv), (v), and (vi) are expressed as a first fusion construct, wherein the first endoplasmic reticulum targeting sequence is located at or near the N-terminus of the first fusion construct and wherein the first endoplasmic reticulum retention sequence is located at or near the C-terminus of the first fusion construct; and wherein (vii) and (viii) are expressed as a second fusion construct, wherein the second endoplasmic reticulum targeting sequence is located at or near the N-terminus of the second fusion construct, and wherein the second endoplasmic reticulum retention sequence is located at or near the C-terminus of the second fusion construct. (i) a first endoplasmic reticulum targeting sequence and a first endoplasmic reticulum retention sequence; (ii) a surface expression sequence; (iii) a first peptide sequence that is a counterselection substrate sequence for the enzyme of (vii); (iv) a first epitope tag sequence; (v) a second peptide sequence that is a selection substrate sequence for the enzyme of (vii); (vi) a second epitope tag sequence; (vii) an enzyme, wherein the enzyme is a protease variant or a protein kinase variant; and (viii) a second endoplasmic reticulum targeting sequence and a second endoplasmic reticulum retention sequence;
A method, in a transmitting device having a plurality of transmitter antennas, for selecting antenna beam-forming precoding vectors for transmissions, the method comprising: transmitting to a receiving device at a first time, using a first beam-forming precoding vector that maps symbols to be transmitted to the plurality of transmitter antennas; monitoring a rotation of the transmitting device; calculating a first threshold based on said monitoring; determining, prior to transmitting to the receiving device at a second time, whether an elapsed time since the first time exceeds the first threshold; selecting one of at least two beam-forming precoding vectors for use in transmitting to the receiving device at the second time, based on said determining; and transmitting to the receiving device at the second time, using the selected one of the at least two beam-forming precoding vectors. transmitting to a receiving device at a first time, using a first beam-forming precoding vector that maps symbols to be transmitted to the plurality of transmitter antennas; monitoring a rotation of the transmitting device; calculating a first threshold based on said monitoring; determining, prior to transmitting to the receiving device at a second time, whether an elapsed time since the first time exceeds the first threshold; selecting one of at least two beam-forming precoding vectors for use in transmitting to the receiving device at the second time, based on said determining; and transmitting to the receiving device at the second time, using the selected one of the at least two beam-forming precoding vectors.
A conveyor drive system comprising: a housing having an interior region and a stationary outer bearing surface surrounding the interior region; a stator housed stationarily in the interior region of the housing along an axis and energizable to produce a magnetic flux wave rotating about the axis; characterised in that the conveyor drive system comprises: a rotor (24,26,48) having an inner bearing surface in contact with the outer bearing surface of the housing, wherein the magnetic flux wave interacts with the rotor (24,26,48) to rotate the rotor about the axis along the outer bearing surface of the housing. a housing having an interior region and a stationary outer bearing surface surrounding the interior region; a stator housed stationarily in the interior region of the housing along an axis and energizable to produce a magnetic flux wave rotating about the axis; characterised in that the conveyor drive system comprises: a rotor (24,26,48) having an inner bearing surface in contact with the outer bearing surface of the housing, wherein the magnetic flux wave interacts with the rotor (24,26,48) to rotate the rotor about the axis along the outer bearing surface of the housing.
A knife cover (1, 1'), wherein the knife cover (1, 1') comprises a frame (3, 3', 3") shaped as a closed loop, which defines on an inside a hole for receiving a blade of a knife in a position where edges of the blade are directed towards the frame (3, 3', 3") surrounding the blade, the hole extending completely through the frame (3, 3', 3") from a first side surface (6, 6") of the frame to a second side surface (7, 7") of the frame (3, 3', 3"), and the knife cover (1, 1') is substantially free of obstacles preventing access to the hole such that substantially the entire surface of the blade of a knife that can be received in the knife cover (1, 1') is accessible from both a side of the first side surface (6, 6") and from a side of the second side surface (7, 7") of the knife cover, characterized in that a first end of the knife cover (1, 1') is provided with a lock (8, 8', 8") having a recess (9, 9', 9") in the first side surface (6, 6') of the frame (3, 3', 3") for receiving a handle of the knife, and for detachably and reattachably attaching the handle to the frame (3, 3', 3"), and that the knife cover (3, 3', 3") is provided with side supports (13, 14) protruding from the frame (3, 3', 3") for supporting opposite side surfaces of the blade of the knife that can be received in the knife cover.
A method for private text chatting, the method comprising: Initiating a private text chat session by a requesting device sending a request to a remote device to establish a private text chat session between the requesting device and the remote device, the private text chat session being defined as a session through which the requesting device and the remote device can exchange private text chat messages; receiving by the requesting device, based on the sending, an acceptance from the remote device accepting the request and in response to said acceptance creating the private text chat session; closing (222, 244), based on one of sending the request or receiving the acceptance, other text chat sessions; presenting at the requesting device, based on the receiving, a separate user interface to conduct the private text chat session; and using the separate user interface to exchange private text chat messages in association with the created private text chat session, the method further comprising at least one of: Suppressing (610, 718), during the private text chat session, indications of at least some notifications; delaying, during the private text chat session, indications of reception of private text chat messages associated with other text chat sessions. Initiating a private text chat session by a requesting device sending a request to a remote device to establish a private text chat session between the requesting device and the remote device, the private text chat session being defined as a session through which the requesting device and the remote device can exchange private text chat messages; receiving by the requesting device, based on the sending, an acceptance from the remote device accepting the request and in response to said acceptance creating the private text chat session; closing (222, 244), based on one of sending the request or receiving the acceptance, other text chat sessions; presenting at the requesting device, based on the receiving, a separate user interface to conduct the private text chat session; and using the separate user interface to exchange private text chat messages in association with the created private text chat session, the method further comprising at least one of: Suppressing (610, 718), during the private text chat session, indications of at least some notifications; delaying, during the private text chat session, indications of reception of private text chat messages associated with other text chat sessions. Suppressing (610, 718), during the private text chat session, indications of at least some notifications; delaying, during the private text chat session, indications of reception of private text chat messages associated with other text chat sessions.
Apparatus for extracting heat from a heat carrier, comprising a heat exchanger, through which, on the one hand, a heat carrier flows and, on the other hand, a fluid to be heated up flows, and comprising a valve for regulating the heat carrier quantity channelled through the heat exchanger, wherein in the heat carrier inlet line to the heat exchanger a first temperature sensor-regulated valve is arranged, of which the allocated first temperature sensor is arranged in a fluid outlet line of the heat exchanger in order to achieve an at least approximately constant fluid outlet temperature, and wherein a second temperature sensor-regulated valve is arranged in a heat carrier outlet line of the heat exchanger, characterised in that the second temperature sensor-regulated valve is allocated a second temperature sensor which is arranged in a fluid inlet line of the heat exchanger in order to limit a desired heat carrier return temperature.
Locking device for a locking fitting for a frame, which is designed to cooperate with a connection fitting for a panel, said locking device having the following features: a) a one-piece or multi-piece main body, b) at least three main functional elements are provided on the locking device, said functional elements being movable at least to a limited extent: i) a release lever, ii) a catch lever (25, 25'), and iii) a force accumulator, c) wherein the catch lever (25, 25') and the release lever are movable in parallel planes and are at least partially in alignment with one another in a view perpendicular to said planes, characterized in that d) one end of the force accumulator passes through a bore and the other end passes through an elongated hole in the main body, in which it is displaceable, e) wherein the other end of the force accumulator, as it moves in the elongated hole of the main body, additionally moves the catch lever into a locking position as the tension of the force accumulator is released. a) a one-piece or multi-piece main body, b) at least three main functional elements are provided on the locking device, said functional elements being movable at least to a limited extent: i) a release lever, ii) a catch lever (25, 25'), and iii) a force accumulator, i) a release lever, ii) a catch lever (25, 25'), and iii) a force accumulator, c) wherein the catch lever (25, 25') and the release lever are movable in parallel planes and are at least partially in alignment with one another in a view perpendicular to said planes, characterized in that d) one end of the force accumulator passes through a bore and the other end passes through an elongated hole in the main body, in which it is displaceable, e) wherein the other end of the force accumulator, as it moves in the elongated hole of the main body, additionally moves the catch lever into a locking position as the tension of the force accumulator is released.
Warp knitting machine of the type of a raschel machine having a knitting needle bar to which knitting needles are fastened, a guide bar to which guide needles are fastened, and a stitch comb bar, wherein the stitch comb bar comprises hold-down devices which are provided for holding down a knitted fabric produced by the warp knitting machine, when the knitting needle bar rises in the direction of the guide bar, the stitch comb bar being connected to the guide bar by at least one supporting body, characterized in that the stitch comb bar is supported exclusively supported by one or more supporting bodies, each of the supporting bodies also supporting a guide bar.
A spinal rod connector comprising: a first arm assembly including a first base portion and a first head portion defining a first slot configured to receive a first spinal rod therein, the first base portion including a hook portion and an extension member; a second arm assembly selectively adjustable with respect to the first arm assembly, the second arm assembly including a second base portion, a second head portion defining a second slot configured to receive a second spinal rod therein, and an elongate member extending from the second base portion, the second base portion including a hook portion, characterized in the extension member including an engagement housing defining a longitudinal axis, the elongate member configured to be selectively received in the engagement housing of the first arm assembly, the elongate member rotatable about an axis offset from the longitudinal axis of the engagement housing; and a fastener configured to be received in the engagement housing to secure the elongate member of the second arm assembly thereto. a first arm assembly including a first base portion and a first head portion defining a first slot configured to receive a first spinal rod therein, the first base portion including a hook portion and an extension member; a second arm assembly selectively adjustable with respect to the first arm assembly, the second arm assembly including a second base portion, a second head portion defining a second slot configured to receive a second spinal rod therein, and an elongate member extending from the second base portion, the second base portion including a hook portion, characterized in the extension member including an engagement housing defining a longitudinal axis, the elongate member configured to be selectively received in the engagement housing of the first arm assembly, the elongate member rotatable about an axis offset from the longitudinal axis of the engagement housing; and a fastener configured to be received in the engagement housing to secure the elongate member of the second arm assembly thereto.
A closure for a container, comprising a first part, a second part relatively movable to the first part to move between a closed condition, in which an opening of the closure is covered, and an open condition, in which the opening is uncovered, and a tamper evidence element that is, on the one hand, connected to the second part by a frangible connection and that is, on the other hand, arranged to be withheld relative to the first part such that, as the second part moves with an opening motion relative to the first part from the closed condition to the open condition, the opening motion ruptures the frangible connection, wherein the tamper evidence element is adapted to be actuated in order to rupture the frangible connection independent of moving the second part relative to the first part by the opening motion, wherein the closure further comprises a holding device arranged on the first part and adapted to secure the tamper evidence element to the first part after the frangible connection has been ruptured, wherein - the first part comprises the opening, and wherein the second part covers, in the closed condition, the opening and uncovers, in the open condition, the opening, or - the second part comprises the opening, and wherein the first part covers, in the closed condition, the opening and uncovers, in the open condition, the opening. a first part, a second part relatively movable to the first part to move between a closed condition, in which an opening of the closure is covered, and an open condition, in which the opening is uncovered, and a tamper evidence element that is, on the one hand, connected to the second part by a frangible connection and that is, on the other hand, arranged to be withheld relative to the first part such that, as the second part moves with an opening motion relative to the first part from the closed condition to the open condition, the opening motion ruptures the frangible connection, wherein the tamper evidence element is adapted to be actuated in order to rupture the frangible connection independent of moving the second part relative to the first part by the opening motion, wherein the closure further comprises a holding device arranged on the first part and adapted to secure the tamper evidence element to the first part after the frangible connection has been ruptured, wherein - the first part comprises the opening, and wherein the second part covers, in the closed condition, the opening and uncovers, in the open condition, the opening, or - the second part comprises the opening, and wherein the first part covers, in the closed condition, the opening and uncovers, in the open condition, the opening. - the first part comprises the opening, and wherein the second part covers, in the closed condition, the opening and uncovers, in the open condition, the opening, or - the second part comprises the opening, and wherein the first part covers, in the closed condition, the opening and uncovers, in the open condition, the opening.
An in vitro method for detecting a WHO grade III or grade IV brain tumor, wherein the method comprises detecting the level of conversion of 5-ALA to protoporphyrin IX (PPIX) associated with brain-derived microparticles in a whole blood or serum sample from a subject to which a pharmaceutical composition comprising 5-aminolevulinic acid (5-ALA) has been administered; thereby detecting the WHO grade III or grade IV brain tumor.
Transparent effect pigment, comprising a non-metal platelet-shaped substrate and a coating applied to the substrate, which coating comprises a) optionally, a layer 1 with an average layer thickness of less than 10 nm, comprising or consisting of tin oxide, tin hydroxide and/or tin oxide hydrate, b) a high refractive index layer 2 with a refractive index n > 1.8 and an average layer thickness in a range of from 30 nm to 300 nm, comprising at least one metal oxide, metal hydroxide and/or metal oxide hydrate, c) a high refractive index layer 3 with a refractive index n > 1.8 and an average layer thickness in a range of from 30 nm to 300 nm, comprising at least one metal oxide, metal hydroxide and/or metal oxide hydrate, and at least one of layers 2 or 3 contains at least two different metal ions and the layers 2 and 3 are interrupted by a spacer layer. a) optionally, a layer 1 with an average layer thickness of less than 10 nm, comprising or consisting of tin oxide, tin hydroxide and/or tin oxide hydrate, b) a high refractive index layer 2 with a refractive index n > 1.8 and an average layer thickness in a range of from 30 nm to 300 nm, comprising at least one metal oxide, metal hydroxide and/or metal oxide hydrate, c) a high refractive index layer 3 with a refractive index n > 1.8 and an average layer thickness in a range of from 30 nm to 300 nm, comprising at least one metal oxide, metal hydroxide and/or metal oxide hydrate,
Photosensitive pixel structure comprising a substrate with a front surface and a back surface, wherein a first material layer is provided at least partially on the back surface of the substrate and the first material layer comprises a reflective layer, characterized in that at least one photosensitive diode (12, 12') is provided on the front surface of the substrate and in that the first material layer on the back surface of the substrate comprises a stack of a layer of titanium and a layer of buried oxide, the thickness of the buried oxide layer being in the range of about 65nm to 210nm or 365nm to 510nm or 665nm to 810 nm.
A method for manufacturing a cross-laminated timber, CLT, panel, the method comprising the following steps: loading CLT panel design data into a manufacturing apparatus; determining based at least in part on the loaded CLT panel design data at least one location to place at least one hollow member in the CLT panel determining based at least in part on the loaded CLT panel design data at least one location of an additional feature to place throughout the CLT panel, providing a first layer, wherein the first layer (102) comprises first boards, the first boards being oriented in a first direction applying adhesive to the first layer; providing a second layer, wherein the second layer (102) comprises second boards; the second boards being oriented in a second direction, the second direction being different than the first direction, wherein the at least one hollow member is arranged in the first layer (102) and/or in the second layer (102) in accordance with the determined location to place the at least one hollow member; the at least one hollow member having substantially the same outside dimensions as the boards of the respective layer; and the at least one hollow member forms a conduit in at least one of the first layer (102) or the second layer (102); and cutting one or more holes in at least the first layer of the panel in order to provide an access point to the at least one hollow member in accordance with the determined location of the additional feature. loading CLT panel design data into a manufacturing apparatus; determining based at least in part on the loaded CLT panel design data at least one location to place at least one hollow member in the CLT panel determining based at least in part on the loaded CLT panel design data at least one location of an additional feature to place throughout the CLT panel, providing a first layer, wherein the first layer (102) comprises first boards, the first boards being oriented in a first direction applying adhesive to the first layer; providing a second layer, wherein the second layer (102) comprises second boards; the second boards being oriented in a second direction, the second direction being different than the first direction, wherein the at least one hollow member is arranged in the first layer (102) and/or in the second layer (102) in accordance with the determined location to place the at least one hollow member; the at least one hollow member having substantially the same outside dimensions as the boards of the respective layer; and the at least one hollow member forms a conduit in at least one of the first layer (102) or the second layer (102); and cutting one or more holes in at least the first layer of the panel in order to provide an access point to the at least one hollow member in accordance with the determined location of the additional feature.
A rope sway restriction device for restricting the swaying of at least one rope connecting an elevator car and a counterweight of an elevator system, the rope sway restriction device comprising: a rope sway restrictor vertically movable within the hoistway; and at least one restrictor rope connecting the rope sway restrictor to the counterweight so that the rope sway restrictor moves vertically within the hoistway in response to movement of the counterweight; wherein the rope sway restrictor includes a pair of movable pulleys (18, 19); characterized in that the movable pulleys (18, 19) are positioned on a surface of a base plate that extends laterally between elevator car guide rails, the surface facing away from the car guide rails. a rope sway restrictor vertically movable within the hoistway; and at least one restrictor rope connecting the rope sway restrictor to the counterweight so that the rope sway restrictor moves vertically within the hoistway in response to movement of the counterweight; wherein the rope sway restrictor includes a pair of movable pulleys (18, 19); characterized in that the movable pulleys (18, 19) are positioned on a surface of a base plate that extends laterally between elevator car guide rails, the surface facing away from the car guide rails.
A phospholipid-protein conjugate, wherein the conjugate is selected from compounds of formula BC-2 and BC-1: wherein b2GPI denotes β2-glycoprotein I, and PT denotes prothrombin.