mhurhangee/ep-ind-claims huggingface dataset:
A method for testing enzyme based electrochemical sensors, wherein the sensors are sensors for quantitative detection of analytes in aqueous solutions, wherein an electrochemical sensor is provided, with a working electrode and a counter electrode, the working electrode comprising an electrical conductor, a solid-state matrix being electrically connected with said conductor and containing an immobilized enzyme able to catalytically convert a primary analyte into a secondary analyte that can be oxidised or reduced when a suitable potential is applied at the working electrode, and a membrane covering said matrix and separating it from the outside, said membrane being permeable for the primary analyte, such that primary analyte molecules present in in an aqueous solution with which the working electrode is contacted can pass through the membrane to the matrix, where they can be catalytically converted into second analyte molecules; a measurement setup is provided, which is operatively coupled to the electrochemical sensor, providing an output signal Z, e.g. a measured signal current, of the electrochemical sensor; and the electrochemical sensor is suitably contacted with, e.g. immersed into, a test solution comprising a certain concentration of the primary analyte; characterized in that the electrochemical sensor is subjected to a certain temperature T, wherein this temperature is swept within a certain range; an output signal Z is measured for different temperature values T; a derivative Z' of the output signal Z as a function of temperature T, or inverse temperature 1/T, is determined; a relative derivate Z'/Z at a certain temperature T, or inverse temperature 1/T, is determined as the ratio between derivative Z' and output signal Z; and wherein the obtained relative derivate Z'/Z values are compared to given calibration data sets corresponding to sensors comprising certain amounts of active enzyme, wherein an increased Z'/Z value indicates a reduced catalytic reaction rate constant and a reduced overall enzyme activity compared to the nominal value.
A method of characterizing a biomarker in a sample, the method comprising: providing a sample comprising a wild-type and a corresponding mutant nucleic acid that is a biomarker for a disease; introducing positive controls to the sample, the positive controls comprising a sequence identical to the mutant nucleic acid and a unique control sequence comprising a number of degenerate bases; amplifying the mutant nucleic acid and the positive controls in the sample; loading the amplified nucleic acid sample and the positive controls on a separation medium, the separation medium comprising an immobilized probe, the immobilized probe comprising a nucleic acid sequence complementary to the mutant nucleic acid; enriching the amplified nucleic acid sample for the mutant nucleic acid and the positive controls over the wild-type nucleic acid by applying a time-varying driving field and a time-varying mobility-varying field to the separation medium; characterizing the enriched nucleic acid in the sample with a technique selected from nucleic acid sequencing, quantitative PCR (qPCR), mass spectrometry, and hybridization assay; and quantifying abundance of the mutant nucleic acid in the provided sample using the positive controls. providing a sample comprising a wild-type and a corresponding mutant nucleic acid that is a biomarker for a disease; introducing positive controls to the sample, the positive controls comprising a sequence identical to the mutant nucleic acid and a unique control sequence comprising a number of degenerate bases; amplifying the mutant nucleic acid and the positive controls in the sample; loading the amplified nucleic acid sample and the positive controls on a separation medium, the separation medium comprising an immobilized probe, the immobilized probe comprising a nucleic acid sequence complementary to the mutant nucleic acid; enriching the amplified nucleic acid sample for the mutant nucleic acid and the positive controls over the wild-type nucleic acid by applying a time-varying driving field and a time-varying mobility-varying field to the separation medium; characterizing the enriched nucleic acid in the sample with a technique selected from nucleic acid sequencing, quantitative PCR (qPCR), mass spectrometry, and hybridization assay; and quantifying abundance of the mutant nucleic acid in the provided sample using the positive controls.
A micro-lattice, comprising: a cellular material formed of a plurality of intersecting hollow tubes, the cellular material having a relative density in a range of 0.001% to 0.3% in relation to the theoretical density of the material; wherein the hollow tubes have a diameter such that the diameter is between 10 and 1000 μm; and wherein the hollow tubes are formed by tube walls having a wall thickness between 0.01 and 2 μm. a cellular material formed of a plurality of intersecting hollow tubes, the cellular material having a relative density in a range of 0.001% to 0.3% in relation to the theoretical density of the material; wherein the hollow tubes have a diameter such that the diameter is between 10 and 1000 μm; and wherein the hollow tubes are formed by tube walls having a wall thickness between 0.01 and 2 μm.
Switchable actuation device for a poppet valve in an internal combustion engine, preferably a gas exchange valve, which is movable indirectly and periodically via a cam of a camshaft between a closed and an open position, comprising: a) a two-piece rocker arm for actuating the poppet valve, comprising a 1) a first rocker arm portion which is mounted pivotably about a rocker arm shaft and on which a bearing sleeve (1a1) is attached concentrically with the rocker arm shaft; and a 2) a second rocker arm portion which is mounted pivotably on the bearing sleeve (1a1); wherein the first rocker arm portion comprises a first cutout, and the second rocker arm portion comprises a second cutout; and b) a coupling device for releasable, rotationally fixed connection of the first and second rocker arm portions (1a, 1b), comprising a locking element, characterized in that the locking element may be brought optionally into and out of engagement with the first and second cutouts (3a, 3b), wherein actuation of the poppet valve is interrupted if the locking element is not in engagement with the first or second cutout (3a, 3b). a) a two-piece rocker arm for actuating the poppet valve, comprising a 1) a first rocker arm portion which is mounted pivotably about a rocker arm shaft and on which a bearing sleeve (1a1) is attached concentrically with the rocker arm shaft; and a 2) a second rocker arm portion which is mounted pivotably on the bearing sleeve (1a1); wherein the first rocker arm portion comprises a first cutout, and the second rocker arm portion comprises a second cutout; and a 1) a first rocker arm portion which is mounted pivotably about a rocker arm shaft and on which a bearing sleeve (1a1) is attached concentrically with the rocker arm shaft; and a 2) a second rocker arm portion which is mounted pivotably on the bearing sleeve (1a1); b) a coupling device for releasable, rotationally fixed connection of the first and second rocker arm portions (1a, 1b), comprising a locking element, characterized in that the locking element may be brought optionally into and out of engagement with the first and second cutouts (3a, 3b), wherein actuation of the poppet valve is interrupted if the locking element is not in engagement with the first or second cutout (3a, 3b).
A bone mill for use with a base unit, said bone mill including: a housing having opposed top and bottom shells (240, 242) that are attached together, the top shell having an inlet opening into which bone stock is introduced into the housing and the bottom shell having an outlet opening spaced away from inlet opening; a cutting device mounted between the housing shells (240, 242) so as to be located between the inlet opening and the outlet opening, the cutting device mounted in the housing for rotation within the housing so as to transform bone stock into bone chips; wherein the cutting device is mounted in the housing to rotate across space in the housing between the inlet and outlet openings so as to transform bone stock into bone chips and to move laterally within the housing and is formed with an alignment feature for engaging a base unit alignment feature so that the engagement of the alignment features results in the lateral positioning of the cutting device so that a base unit spindle can engage and rotate the cutting device. a housing having opposed top and bottom shells (240, 242) that are attached together, the top shell having an inlet opening into which bone stock is introduced into the housing and the bottom shell having an outlet opening spaced away from inlet opening; a cutting device mounted between the housing shells (240, 242) so as to be located between the inlet opening and the outlet opening, the cutting device mounted in the housing for rotation within the housing so as to transform bone stock into bone chips;
A method for producing carbonated beverages, the method comprising generating cavitation in a liquid containing carbon dioxide gas present under pressure conditions by passing the liquid through an apparatus to generate cavitation, wherein the apparatus to generate cavitation is a micro/nano bubble generator, and wherein the micro/nano bubble generator has a flow channel for the pressurized liquid having at least one step portion which makes the diameter of the channel increased discontinuously toward the downstream side, whereby the generation of cavitation is done by using said flow channel.
A valve, in particular a pilot-operated proportional directional poppet valve, that has a valve housing which has a fluid inlet and a fluid outlet, the fluid stream between the fluid inlet and the fluid outlet being adjustable by means of a main piston, a pilot valve chamber provided on a rear face of the main piston having a pilot valve closing member which may be moved by an actuating device and by means of which the fluid stream between the pilot valve chamber and the fluid outlet can be adjusted, a supply aperture being disposed between the fluid inlet and the pilot valve chamber, the opening cross-section of the supply aperture being able to be reduced by a control element, characterised in that the supply aperture has a plurality of aperture bores (39, 41) and that the opening cross-section of at least one of the aperture bores (39, 41) can be reduced by the control element, the splitting up of the supply aperture into a plurality of aperture bores making it possible to control the supply aperture in a plurality of opening stages.
Photovoltaic module comprising one or more bifacial PV cells, which module comprises a front side and a rear side, wherein the front side is designed for receiving direct sunlight, and the rear side made of a transparent material comprises a rear surface carrying a structured layer, wherein a rear surface of the structured layer forms the rear surface of the module's rear side or a fraction of said rear side and is structured by parallel V-shaped grooves, characterized in that each pair of neighbouring V-shaped grooves comprises one groove of depth h2 and one groove whose depth equals h2 - h1, h2 is from the range 5 to 200 micrometer, especially 10 to 60 micrometer, h1 ranges from 0.1 times h2 to 0.9 times h2, preferably from 0.1 times h2 to 0.8 times h2, and wherein the lateral faces of said grooves of depth h2 - h1 form a groove angle beta and adjacent faces of neighbouring grooves form a peak of apex angle alpha. each pair of neighbouring V-shaped grooves comprises one groove of depth h2 and one groove whose depth equals h2 - h1, h2 is from the range 5 to 200 micrometer, especially 10 to 60 micrometer, h1 ranges from 0.1 times h2 to 0.9 times h2, preferably from 0.1 times h2 to 0.8 times h2, and wherein the lateral faces of said grooves of depth h2 - h1 form a groove angle beta and adjacent faces of neighbouring grooves form a peak of apex angle alpha.
A system for delivery of a therapeutic device, comprising: an energy source; a thermally responsive element connected to the energy source; a polymeric element adjacent to the thermally responsive element; a therapeutic device; and an anchor that retains the therapeutic device to the polymeric element, wherein the polymeric element comprises an aggregate portion connected to the anchor, wherein the anchor is secured to the aggregate portion in the molding process of the polymeric element or affixed by adhesives, solder or welding, and characterized by a bulb that secures a tether portion of the polymeric element to the thermally responsive element and to the energy source. an energy source; a thermally responsive element connected to the energy source; a polymeric element adjacent to the thermally responsive element; a therapeutic device; and an anchor that retains the therapeutic device to the polymeric element, wherein the polymeric element comprises an aggregate portion connected to the anchor, wherein the anchor is secured to the aggregate portion in the molding process of the polymeric element or affixed by adhesives, solder or welding, and characterized by a bulb that secures a tether portion of the polymeric element to the thermally responsive element and to the energy source. wherein the polymeric element comprises an aggregate portion connected to the anchor, wherein the anchor is secured to the aggregate portion in the molding process of the polymeric element or affixed by adhesives, solder or welding, and characterized by a bulb that secures a tether portion of the polymeric element to the thermally responsive element and to the energy source.
An adaptable ostomy base plate comprising a flexible top film, having a first section and a second section, and having at least a first elastic skin-friendly adhesive on a proximal surface of said flexible top film, a stoma-receiving through-going hole defining an inner boundary in said first section, said first section being adjacent to and extending radially from said through-going hole and said second section surrounding said first section defining an outer boundary of the base plate, and one or more release liners, the base plate has a substantially convex shape for initial engagement with a peristomal skin surface, the base plate being invertible to a substantially concave shape to fittingly engage to a topography of the peristomal skin surface for permanent engagement thereto and wherein said second section of the base plate is in the form of a plurality of petals extending away from the central area; and a plurality of bridges, each bridge formed between adjacent petals of the plurality of petals and wherein the ostomy base plate is provided with a reinforcement structure arranged in a radial direction between the inner and outer radial boundary of the base plate wherein the reinforcing structure has an inner radial periphery and an outer radial periphery, and the reinforcing structure is attached to the distal surface of the base plate along the outer periphery of the structure, leaving the inner periphery unattached, characterised in that the release liner(s) has a thickness of 0.1 mm to 0.2 mm and is form stable and able to fix the concave contour of the base plate.
Heatable laminated vehicle window for separating a vehicle interior from an outer surrounding area, comprising an outer pane and an inner pane that are bonded to one another via a thermoplastic intermediate layer and an electrically heatable coating that is electrically connected to at least two busbars (5,6) provided for electrical connecting to the two poles of a voltage source such that by applying a supply voltage, a heating current flows via a heating field formed between the at least two busbars (5,6), wherein the vehicle window is equipped with at least one metal element that is arranged on or in the vehicle window such that heat is dissipated out of a region of the heating field with elevated heat generation by means of thermal conduction of the metal element.
Improved ceramic material burning system comprising a furnace having insulated walls and being divided into different regions with different temperatures, a firing zone of the burning system further comprising a plurality of injectors divided into groups, each injector comprising a controlling device and each group of injectors being activated at preset time intervals, controlled by a programmable logic controller, characterized in that the burning system further comprises an air recirculator at the exit of the furnace to increase the temperature of cooling air injected into a cooling zone.
Electrical distribution box (1, 2) for an aircraft comprising first housings (4, 24) for receiving power modules and second housings (5, 25) for receiving electronic control modules, and an interface (6, 26) for making the connections between the various modules and external electrical elements, characterized in that the interface (6, 26) comprises at least one input power busbar (7, 27) extending into at least a first housing (4, 24) so as to be able to be connected to at least one power module, an input busbar (7, 27) being capable of being connected to a cable of a wiring harness in such a way as to connect at least one power module to the electrical harness.
A method for increasing the production of flowers, seeds and/or fruits in a plant, comprising the step of contacting said plant with a composition, the composition comprising the microorganism Colletotrichum tofieldiae and/or filtrates of said microorganism.
An apparatus for treating an eye having a cornea, the apparatus comprising: a cornea profiling system to measure a profile of a posterior surface of the cornea; a laser to generate a laser beam; and a processor comprising a tangible medium coupled to the laser and configured to receive data from the cornea profiling system, the tangible medium embodying instructions to cause the processor to determine an incision profile based on the posterior surface of the cornea; and characterised in that the processor embodies instructions of a computer program to determine a first beam pulse profile to incise a donor cornea based on a posterior surface profile of the donor cornea and a second beam pulse profile to incise the recipient cornea based on the posterior surface profile of the recipient cornea, and wherein the first beam pulse profile provides a first thickness of a graft tissue to be excised from the donor cornea and the second beam pulse profile provides a second thickness of a flap of tissue to be removed from the recipient cornea to form a bed receiving the graft tissue; and wherein the first thickness is substantially similar to the second thickness in order to inhibit resection of donor lamella of the graft and resection of the recipient lamella of a bed of the recipient cornea.
A bed sheet comprising a circular knitted performance fabric having a plurality of spaced apart ventilation ports, the circular knitted performance fabric having a gauge, weight, air permeability and material content that are pre-selected to provide the circular knitted performance fabric with one or more selected physical features, wherein the bed sheet extends from a top end to an opposite bottom end and has opposite first and second side surfaces (38, 40) that each extend between the top and bottom ends, and wherein the circular knitted performance fabric comprises at least 7.7 of the ventilation ports per square centimetre (at least 50 per square inch). wherein the bed sheet extends from a top end to an opposite bottom end and has opposite first and second side surfaces (38, 40) that each extend between the top and bottom ends, and wherein the circular knitted performance fabric comprises at least 7.7 of the ventilation ports per square centimetre (at least 50 per square inch).
A system for detecting an unauthorized use of a vehicle, the system comprising a vehicle computing system configured to: store one or more facial images of one or more authorized drivers of a vehicle; detect movement of the vehicle; after movement of the vehicle, periodically receive one or more facial images of a driver of the vehicle from at least one in-vehicle camera; periodically process the one or more captured facial images of the driver based on the stored facial images of the one or more authorized drivers to determine if the driver is an authorized driver; if the driver is not an authorized driver based on the periodic determination, disable vehicle operation; and if the driver is authorized based on the periodic determination, enable continued operation of the vehicle, wherein the vehicle computing system configured to process the captured facial images is further configured to: send instructions to one or more in-vehicle cameras to scan an image field to detect a presence in the vehicle of at least one vehicle occupant other than the driver; determine a status of the at least one vehicle occupant as an authorized driver if detected based on the scan; and based on the status of the at least one detect vehicle occupant, determine if the driver is an authorized driver. store one or more facial images of one or more authorized drivers of a vehicle; detect movement of the vehicle; after movement of the vehicle, periodically receive one or more facial images of a driver of the vehicle from at least one in-vehicle camera; periodically process the one or more captured facial images of the driver based on the stored facial images of the one or more authorized drivers to determine if the driver is an authorized driver; if the driver is not an authorized driver based on the periodic determination, disable vehicle operation; and if the driver is authorized based on the periodic determination, enable continued operation of the vehicle, wherein the vehicle computing system configured to process the captured facial images is further configured to: send instructions to one or more in-vehicle cameras to scan an image field to detect a presence in the vehicle of at least one vehicle occupant other than the driver; determine a status of the at least one vehicle occupant as an authorized driver if detected based on the scan; and based on the status of the at least one detect vehicle occupant, determine if the driver is an authorized driver. send instructions to one or more in-vehicle cameras to scan an image field to detect a presence in the vehicle of at least one vehicle occupant other than the driver; determine a status of the at least one vehicle occupant as an authorized driver if detected based on the scan; and based on the status of the at least one detect vehicle occupant, determine if the driver is an authorized driver.