An extraction method for preparing analytes for molecular analysis comprising the steps of: placing an extraction sample having a sample matrix containing an analyte in a heat conductive sample cup surrounded by a reaction chamber with the heat conductive sample cup having one open filtered end and a mouth opposite from its open filtered end, and an outlet valve being provided in the reaction chamber; sealing the mouth of the sample cup between a sealing cover at the mouth and an outlet valve in the reaction chamber; adding liquid extraction solvent to both the inside of the sample cup and to the reaction chamber outside of the sample cup; and heating the liquid extraction solvent in the reaction chamber outside of the sample cup to in turn heat the sample cup, heat the liquid extraction solvent inside the sample cup, and heat the extraction sample inside the sample cup until the temperature generates an above-atmospheric pressure that together with the increased temperature drives the analyte substantially from the sample matrix into the liquid extraction solvent; releasing the outlet valve on the reaction chamber so that the vapor pressure in the reaction chamber drives the liquid solvent extract out of the sample cup through the open filtered end and through the outlet valve into a cooling coil in liquid communication with the outlet valve in the reaction chamber, wherein the release of the solvent extract to atmospheric pressure drives the solvent extract into the cooling coil and wherein the cooling coil has a length sufficient to reduce the temperature of the solvent extract to ambient or near-ambient temperature in the coil; and collecting the filtered solvent extract from the coil. placing an extraction sample having a sample matrix containing an analyte in a heat conductive sample cup surrounded by a reaction chamber with the heat conductive sample cup having one open filtered end and a mouth opposite from its open filtered end, and an outlet valve being provided in the reaction chamber; sealing the mouth of the sample cup between a sealing cover at the mouth and an outlet valve in the reaction chamber; adding liquid extraction solvent to both the inside of the sample cup and to the reaction chamber outside of the sample cup; and heating the liquid extraction solvent in the reaction chamber outside of the sample cup to in turn heat the sample cup, heat the liquid extraction solvent inside the sample cup, and heat the extraction sample inside the sample cup until the temperature generates an above-atmospheric pressure that together with the increased temperature drives the analyte substantially from the sample matrix into the liquid extraction solvent; releasing the outlet valve on the reaction chamber so that the vapor pressure in the reaction chamber drives the liquid solvent extract out of the sample cup through the open filtered end and through the outlet valve into a cooling coil in liquid communication with the outlet valve in the reaction chamber, wherein the release of the solvent extract to atmospheric pressure drives the solvent extract into the cooling coil and wherein the cooling coil has a length sufficient to reduce the temperature of the solvent extract to ambient or near-ambient temperature in the coil; and collecting the filtered solvent extract from the coil.