mhurhangee/ep-ind-claims huggingface dataset:
Process for producing preparations comprising one or more mononuclear platinum complex compounds of formula [olefin1] x [olefin2] y Pt 2+ Hal - 2, where Hal = F, Cl, Br or I, x = 1 or 2, y = 0 or 1, olefin1 = compound comprising at least one olefinic unsaturation and fewer than two oxygen atoms, olefin2 = compound comprising an olefinic unsaturation and fewer than two oxygen atoms, and with the proviso that when olefin1 comprises at least two olefinic unsaturations x = 1 and x + y = 1 and when olefin1 comprises only one olefinic unsaturation x + y = 2, one or more compounds comprising carbon atoms, hydrogen atoms and at least two oxygen atoms as compound(s) from compound class II, and one or more olefinically unsaturated compound(s) selected from olefin1 and olefin2 as compound(s) from compound class III, by contacting at least one compound from each of compound classes II and III with one or more dinuclear platinum compound(s) as compound(s) from compound class I, characterized in that it comprises producing the preparation by performing a first step of preparing a mixture by adding together at least two compounds selected from two different compound classes and a subsequent step of admixing the mixture obtained in the first step with one or more compounds of the still absent compound class. Hal = F, Cl, Br or I, x = 1 or 2, y = 0 or 1, olefin1 = compound comprising at least one olefinic unsaturation and fewer than two oxygen atoms, olefin2 = compound comprising an olefinic unsaturation and fewer than two oxygen atoms, and with the proviso that when olefin1 comprises at least two olefinic unsaturations x = 1 and x + y = 1 and when olefin1 comprises only one olefinic unsaturation x + y = 2, one or more compounds comprising carbon atoms, hydrogen atoms and at least two oxygen atoms as compound(s) from compound class II, and one or more olefinically unsaturated compound(s) selected from olefin1 and olefin2 as compound(s) from compound class III, by contacting at least one compound from each of compound classes II and III with one or more dinuclear platinum compound(s) as compound(s) from compound class I, characterized in that it comprises producing the preparation by performing a first step of preparing a mixture by adding together at least two compounds selected from two different compound classes and a subsequent step of admixing the mixture obtained in the first step with one or more compounds of the still absent compound class.
Process for purifying acidic, preferably superacidic, in particular trifluoromethanesulfonic acid-acidified, equilibrated, preferably end-equilibrated, acetic anhydride-containing acetoxysiloxanes, characterized in that (a) the acidic, preferably superacidic, in particular trifluoromethanesulfonic acid-acidified, acetic anhydride-containing and optionally acetic acid-containing equilibrated, preferably end-equilibrated acetoxysiloxane, which is optionally dissolved in an inert solvent, is contacted with a base, (b) the precipitate is filtered off and (c) the filtrate obtained is optionally purified by distillation. (a) the acidic, preferably superacidic, in particular trifluoromethanesulfonic acid-acidified, acetic anhydride-containing and optionally acetic acid-containing equilibrated, preferably end-equilibrated acetoxysiloxane, which is optionally dissolved in an inert solvent, is contacted with a base, (b) the precipitate is filtered off and (c) the filtrate obtained is optionally purified by distillation.
A method of fabricating a semiconductor structure, comprising: forming a nanocrystalline core from a first semiconductor material; forming at least one nanocrystalline shell from a second, different, semiconductor material that at least partially surrounds the nanocrystalline core, wherein the nanocrystalline core and the nanocrystalline shell(s) form a quantum dot; forming an insulator layer, comprising a silica layer, encapsulating the quantum dot to create a coated quantum dot; and forming at least one additional insulator layer, comprising a silica layer, on the coated quantum dot, wherein after forming the insulator layer encapsulating the quantum dot to create a coated quantum dot, and prior to forming the at least one additional insulator layer on the coated quantum dot, treating the coated quantum dot with a base, wherein after the treatment with the base removing an excess of the base, and wherein forming the insulator layer encapsulating the quantum dot to create a coated quantum dot comprises forming a first insulator layer encapsulating the quantum dot using a reverse micelle sol-gel reaction; and wherein forming the additional insulator layers on the coated quantum dot comprises forming an additional insulating layer encapsulating the quantum dot using a reverse micelle sol-gel process using Igepal, a direct micelle sol-gel process using dioctyl sodium sulfosuccinate, or a Stober sol-gel process. forming a nanocrystalline core from a first semiconductor material; forming at least one nanocrystalline shell from a second, different, semiconductor material that at least partially surrounds the nanocrystalline core, wherein the nanocrystalline core and the nanocrystalline shell(s) form a quantum dot; forming an insulator layer, comprising a silica layer, encapsulating the quantum dot to create a coated quantum dot; and forming at least one additional insulator layer, comprising a silica layer, on the coated quantum dot, wherein after forming the insulator layer encapsulating the quantum dot to create a coated quantum dot, and prior to forming the at least one additional insulator layer on the coated quantum dot, treating the coated quantum dot with a base, wherein after the treatment with the base removing an excess of the base, and wherein forming the insulator layer encapsulating the quantum dot to create a coated quantum dot comprises forming a first insulator layer encapsulating the quantum dot using a reverse micelle sol-gel reaction; and wherein forming the additional insulator layers on the coated quantum dot comprises forming an additional insulating layer encapsulating the quantum dot using a reverse micelle sol-gel process using Igepal, a direct micelle sol-gel process using dioctyl sodium sulfosuccinate, or a Stober sol-gel process.
A hydraulic binder comprising in mass percent: - from 20 to 82 % of a Portland cement the particles of which have a D 50 comprised from 2 μm to 11 μm; - from 15 to 56 % of a non-pozzolanic mineral addition A1, the particles of which have a D 50 comprised from 1 to 150 μm and selected from among limestone additions such as calcium carbonate, siliceous additions such as quartz, siliceous limestone mineral additions, calcined shales, zeolites, burnt plant ashes, and mixtures thereof; - from 4 to 30 % of pozzolanic mineral addition A2, the particles of which have a D 50 comprised from 1 to 150 μm; the sum of these percentages being comprised from 90 to 100%. - from 20 to 82 % of a Portland cement the particles of which have a D 50 comprised from 2 μm to 11 μm; - from 15 to 56 % of a non-pozzolanic mineral addition A1, the particles of which have a D 50 comprised from 1 to 150 μm and selected from among limestone additions such as calcium carbonate, siliceous additions such as quartz, siliceous limestone mineral additions, calcined shales, zeolites, burnt plant ashes, and mixtures thereof; - from 4 to 30 % of pozzolanic mineral addition A2, the particles of which have a D 50 comprised from 1 to 150 μm;
A compound that inhibits VEGF-B signaling for use in treating diabetic nephropathy in a subject suffering from diabetic nephropathy, wherein the compound that inhibits VEGF-B signaling is: (i) a protein comprising an antibody variable region that binds to or specifically binds to VEGF-B and neutralizes VEGF-B signaling; or (ii) a nucleic acid that inhibits or prevents expression of VEGF-B. (i) a protein comprising an antibody variable region that binds to or specifically binds to VEGF-B and neutralizes VEGF-B signaling; or (ii) a nucleic acid that inhibits or prevents expression of VEGF-B.
A gas streaming device for use between an injection port and a mixing chamber within an airlift pump, the device comprising: a planar body such as a plate, the planar body with multiple holes extending therethrough, the holes dimensioned to direct the gas into multiple streams for streaming the gas from the injection port into the mixing chamber, characterized in that the holes in the body contain a helical groove pattern to gyroscopically stabilize the gas flow as it leaves the body. a planar body such as a plate, the planar body with multiple holes extending therethrough, the holes dimensioned to direct the gas into multiple streams for streaming the gas from the injection port into the mixing chamber, characterized in that the holes in the body contain a helical groove pattern to gyroscopically stabilize the gas flow as it leaves the body.
Method for regenerating the capacity of a metal-ion electrochemical accumulator, including at least one electrochemical cell including a cathode, an anode and a separator impregnated with an electrolyte between the anode and the cathode, two current collectors, one of which is connected to the anode and the other of which is connected to the cathode, and a casing suitable for housing the electrochemical cell in a sealtight manner while having a portion of the current collectors forming the output terminals passing therethrough, the cell being wound up on itself around a winding axis, referred to as a core, including at least one zone for storing metal ions, the core being made of electrochemically lithiated aluminium with a degree of lithiation of at most 30%, electrical continuity being provided between the storage zone and the exterior of the accumulator, the method including the following steps: a) evaluating the quantity of exchangeable metal ions, b) if the evaluated quantity of metal ions is smaller than or equal to a threshold value, applying an electric current between the cathode or the anode and the core so as to bring about the disinsertion of metal ions from the core and thereby insertion into the active electrochemical material of the anode and/or of the cathode, an element that is both an electrical insulator and an ion conductor additionally being arranged between the anode and cathode electrodes on one side and the core on the other side. a) evaluating the quantity of exchangeable metal ions, b) if the evaluated quantity of metal ions is smaller than or equal to a threshold value, applying an electric current between the cathode or the anode and the core so as to bring about the disinsertion of metal ions from the core and thereby insertion into the active electrochemical material of the anode and/or of the cathode, an element that is both an electrical insulator and an ion conductor additionally being arranged between the anode and cathode electrodes on one side and the core on the other side.
A method of preparing a compound of Formula II, or a salt thereof: comprising contacting a compound of Formula II-A: with a compound of Formula II-B: under reaction conditions to form the compound of Formula II or the salt thereof; whe rein R 1 and R 2 are independently C 1-6 alkyl; R 3 and R 4 are independently selected from the group consisting of hydrogen, fluoro, chloro, bromo, and methoxy; and R 5 is selected from the group consisting of fluoro, chloro, bromo, and methoxy. R 1 and R 2 are independently C 1-6 alkyl; R 3 and R 4 are independently selected from the group consisting of hydrogen, fluoro, chloro, bromo, and methoxy; and R 5 is selected from the group consisting of fluoro, chloro, bromo, and methoxy.
A measurement gap indication method, comprising obtaining, by a user equipment, UE, measurement-related information and configuration information of a target parameter configured by a network device for the UE; according to measuring object, reference signal configuration corresponding to the measuring object and configuration of measurement time window included in the measurement-related information and the configuration information, obtaining, by the UE, indication information of whether a measurement gap is required when the UE operates with the target parameter; and transmitting, by the UE, the indication information to the network device; wherein the target parameter comprises at least one of carrier, carrier frequency band combination, bandwidth part, bandwidth part combination and reference signal. obtaining, by a user equipment, UE, measurement-related information and configuration information of a target parameter configured by a network device for the UE; according to measuring object, reference signal configuration corresponding to the measuring object and configuration of measurement time window included in the measurement-related information and the configuration information, obtaining, by the UE, indication information of whether a measurement gap is required when the UE operates with the target parameter; and transmitting, by the UE, the indication information to the network device; wherein the target parameter comprises at least one of carrier, carrier frequency band combination, bandwidth part, bandwidth part combination and reference signal.
A guide assembly comprising: a guide including a body and a joint including at least one through hole, the joint configured for sliding along the length of the body; and a first surgical device, wherein the body includes a first attachment portion located at a first end of the body and a second attachment portion located away from the first end and a second end of the body, and the first attachment portion and the second attachment portion couple the body to the first surgical device and, a longitudinal axis of the through hole is co-radial with an end of the first surgical device regardless of the position of the joint along the length of the body so that a second surgical device having a longitudinal axis can be disposed within the through hole so that the longitudinal axis of the second surgical device is co-radial with an end of the first surgical device. a guide including a body and a joint including at least one through hole, the joint configured for sliding along the length of the body; and a first surgical device, wherein the body includes a first attachment portion located at a first end of the body and a second attachment portion located away from the first end and a second end of the body, and the first attachment portion and the second attachment portion couple the body to the first surgical device and, a longitudinal axis of the through hole is co-radial with an end of the first surgical device regardless of the position of the joint along the length of the body so that a second surgical device having a longitudinal axis can be disposed within the through hole so that the longitudinal axis of the second surgical device is co-radial with an end of the first surgical device.
An electronic cigarette comprising a battery stick, a vaporizer assembly and a mouth piece that are connected together, the battery stick comprises a battery, a casing tube of the battery stick for sheathing the battery, and a first connection portion arranged at an end of the casing tube of the battery stick adjacent to the vaporizer assembly; the vaporizer assembly comprises a vaporizer, and a casing tube of the vaporizer for sheathing the vaporizer in an inner cavity of the casing tube; the vaporizer comprises a vaporizer tube body, and a second connection portion arranged at an end of the vaporizer tube body adjacent to the battery stick; a third connection portion is arranged at an end of the casing tube of the vaporizer adjacent to the battery stick; characterized in that the second connection portion and the first connection portion abut against each other to be connected, the third connection portion is detachably connected to the first connection portion by means of a screw thread.
A compound represented by the following general formula: wherein R 1 represents an alkyl group having 1 to 12 carbon atoms; an arylalkynyl group having 8 to 16 carbon atoms which may be substituted with a halogen atom, an alkyl group having 1 to 6 carbon atoms, an alkoxy group having 1 to 6 carbon atoms, or an alkylthio group having 1 to 6 carbon atoms; an alkenyl group having 2 to 12 carbon atoms; a 2-furylethynyl group; a 2-thiophenylethynyl group; or a 2,6-dithianyl group; R 2 to R 4 each independently represent an alkyl group having 1 to 12 carbon atoms; an arylalkynyl group having 8 to 16 carbon atoms which may be substituted with a halogen atom, an alkyl group having 1 to 6 carbon atoms, an alkoxy group having 1 to 6 carbon atoms, or an alkylthio group having 1 to 6 carbon atoms; an aryl group having 6 to 14 carbon atoms which may be substituted with a halogen atom, an alkyl group having 1 to 6 carbon atoms, an alkoxy group having 1 to 6 carbon atoms, or an alkylthio group having 1 to 6 carbon atoms; a furanyl group; a thienyl group; or an N-alkyl-substituted pyrrolyl group; and Z + represents an ammonium cation having a biguanidium group represented by the following general formula (B 2): wherein R 11 to R 15 and R 18 each independently represent a hydrogen atom or an alkyl group having 1 to 12 carbon atoms, R 16 and R 17 each independently represent a hydrogen atom, an alkyl group having 1 to 12 carbon atoms, or an aryl group having 6 to 14 carbon atoms which may be substituted with a nitro group, an alkyl group having 1 to 6 carbon atoms, an alkoxy group having 1 to 6 carbon atoms, an alkylthio group having 1 to 6 carbon atoms, or a dialkylamino group having 1 to 12 carbon atoms; R 16 together with R 17 may form an alkylene group having 2 to 4 carbon atoms, and number of hydrogen atoms among R 11 to R 18 is 0 to 2.
An apparatus comprising: a flux sensor; a rotating component, wherein the rotating component is configured to rotate with a shaft of a driven machine; a driven machine bearing housing, the flux sensor being arranged on, or in relation to, the driven machine bearing housing; one or more rotating magnets (24a, 24e, 24h) placed on the rotating component, wherein the rotating component comprises a bearing isolator having a stationary part and a rotating part with the one or more rotating magnets placed therein; and a signal processor configured to receive signaling from the flux sensor containing information about both a residual field from an electrical supply to a motor of the driven machine and a magnetic field from the one or more rotating magnets placed on the rotating component of the driven machine; and determine corresponding signaling containing information about the operation of the driven machine, based upon a difference between an electrical supply frequency and a slip frequency determined from the signaling received and processed. a flux sensor; a rotating component, wherein the rotating component is configured to rotate with a shaft of a driven machine; a driven machine bearing housing, the flux sensor being arranged on, or in relation to, the driven machine bearing housing; one or more rotating magnets (24a, 24e, 24h) placed on the rotating component, wherein the rotating component comprises a bearing isolator having a stationary part and a rotating part with the one or more rotating magnets placed therein; and a signal processor configured to receive signaling from the flux sensor containing information about both a residual field from an electrical supply to a motor of the driven machine and a magnetic field from the one or more rotating magnets placed on the rotating component of the driven machine; and determine corresponding signaling containing information about the operation of the driven machine, based upon a difference between an electrical supply frequency and a slip frequency determined from the signaling received and processed.
Extractor hood, in particular a vertical hood, comprising a platform device that comprises at least one housing device and at least one fan device, the housing device comprising at least one receiving portion for at least one vapour-conducting device of a frontal screen device, which portion is designed such that at least one lower portion of the receiving portion of the housing device is next to the wall and at least one upper portion of the receiving portion of the housing device is remote from the wall when installed, and the fan device comprising at least one suction portion and at least one blow-out portion, the housing device being suitable and designed for receiving the fan device depending on the installation position of the extractor hood such that the blow-out portion of the fan device removes the air delivered by the fan device through at least a first outlet of the housing device or through at least a second outlet of the housing device, the first outlet being oriented to the rear and the second outlet being oriented upwards, characterised in that, when installed, the front face of the platform device consists substantially of the suction surface, which is designed as a decorative panel, and the frontal screen device comprises two vapour-conducting devices, and the platform device comprises one receiving portion on either side of the suction surface for releasably fastening a vapour-conducting device, the two vapour-conducting devices being arranged to the left and to the right of the suction surface.
A cartridge for preparation of drinks suitable to be inserted in an infusion chamber of a machine which exhibits an axial size that is smaller than the axial size (height) of the cartridge, and comprising a body, beaker-shaped and made of a waterproof material, and a substance for preparation of the drink contained internally of the beaker body, characterised in that the lateral wall of the beaker body comprises at least a resilient zone made of an elastically yielding material, said zone having controlled deformation and destined to yield elastically following an axial compression externally on the cartridge and to exert an axial elastic thrust reaction, wherein the resilient zone comprises a step realised at the lateral wall of the beaker-shaped body, the step dividing the lateral wall into three consecutive tracts (114,115,116), the second tract being inclined with respect to the axial direction.
A water soluble propofol derivative of general formula: wherein, X is H or F; Y is F or alkyl substituted with one or more F; n is 1, 2, 3, 4, 5 or 6; W is W 1 or W 2; W 1 isNR 1 R 2 ·A or R 1, R 2 are each independently H, alkyl optionally substituted with phenyl, or cycloalkyl; m is 0, 1, 2 or 3; A is a pharmaceutically acceptable acid; W 2 is COOM 1/t or PO 3 2/t; M is a metal ion, an ammonium ion or a basic amino acid cation which can form a salt with an acid radical; and t is the charge number of M. X is H or F; Y is F or alkyl substituted with one or more F; n is 1, 2, 3, 4, 5 or 6; W is W 1 or W 2; W 1 isNR 1 R 2 ·A or R 1, R 2 are each independently H, alkyl optionally substituted with phenyl, or cycloalkyl; m is 0, 1, 2 or 3; A is a pharmaceutically acceptable acid; W 2 is COOM 1/t or PO 3 2/t; M is a metal ion, an ammonium ion or a basic amino acid cation which can form a salt with an acid radical; and t is the charge number of M.
A method of diagnosing an anaplastic lymphoma kinase related cancer in a subject, the method comprising conducting a nucleic acid amplification process on a tissue sample from the subject and detecting the presence of wild-type ALK kinase domain nucleic acid in the tissue sample using a primer pair, wherein the primer pair used in the amplification process consists of a forward primer and reverse primer that specifically hybridize to the wild-type kinase domain of ALK; and wherein the presence of wild-type ALK kinase domain nucleic acid indicates the presence of an ALK related cancer; and wherein the cancer is selected from the group consisting of breast cancer, ovarian cancer, colorectal carcinoma, non-small cell lung carcinoma, diffuse large B-cell lymphoma, esophageal squamous cell carcinoma, anaplastic large-cell lymphoma, inflammatory myofibroblastic tumors and malignant histiocytosis.