mhurhangee/ep-ind-claims huggingface dataset:
An oligomeric compound comprising an oligonucleotide consisting of 8-80 linked nucleosides, wherein the oligonucleotide comprises a phosphate stabilizing nucleoside at the 5'-end, wherein the phosphate stabilizing nucleoside comprises: a 5'-terminal modified phosphate selected from phosphonate, alkylphosphonate and substituted alkylphosphonate or a 5'-terminal unmodified phosphate; a modified sugar moiety comprising: a 5'-modification and a 2'-modification; and a linking group linking the phosphate stabilizing nucleoside to the remainder of the oligonucleotide selected from phosphodiester and phosphorothioate; and wherein the remainder of the oligonucleotide comprises at least one region having a nucleoside motif: n - n - n - n, wherein: A and B are differently modified nucleosides; and each n is independently selected from 1, 2, 3, 4, and 5; and wherein the oligomeric compound is an antisense compound, wherein the antisense compound is a single-stranded RNAi compound. a 5'-terminal modified phosphate selected from phosphonate, alkylphosphonate and substituted alkylphosphonate or a 5'-terminal unmodified phosphate; a modified sugar moiety comprising: a 5'-modification and a 2'-modification; and a linking group linking the phosphate stabilizing nucleoside to the remainder of the oligonucleotide selected from phosphodiester and phosphorothioate; and wherein the remainder of the oligonucleotide comprises at least one region having a nucleoside motif: n - n - n - n, wherein: A and B are differently modified nucleosides; and each n is independently selected from 1, 2, 3, 4, and 5; and wherein the oligomeric compound is an antisense compound, wherein the antisense compound is a single-stranded RNAi compound. a 5'-modification and a 2'-modification; and a linking group linking the phosphate stabilizing nucleoside to the remainder of the oligonucleotide selected from phosphodiester and phosphorothioate; and wherein the remainder of the oligonucleotide comprises at least one region having a nucleoside motif: n - n - n - n, wherein: A and B are differently modified nucleosides; and each n is independently selected from 1, 2, 3, 4, and 5; and wherein the oligomeric compound is an antisense compound, wherein the antisense compound is a single-stranded RNAi compound. A and B are differently modified nucleosides; and each n is independently selected from 1, 2, 3, 4, and 5; and wherein the oligomeric compound is an antisense compound, wherein the antisense compound is a single-stranded RNAi compound.
A compound comprising a TLR2 agonist for use in treating or preventing a respiratory condition associated with rhinovirus in a subject, wherein the TLR2 agonist comprises a lipopeptide or a lipid moiety, wherein the lipid moiety is selected from palmitoyl, myristoyl and stearoyl, and wherein the TLR2 agonist is linked to a solubilising moiety, wherein the solubilising moiety comprises a polyethyleneglycol.
A multiple input multiple output, MIMO, signal receiving apparatus comprising: a first antenna for receiving a first radio frequency, RF, signal; a second antenna for receiving a second RF signal; a superheterodyne receiver for converting one or all of the first and second RF signals into at least one first analog signal; a direct conversion receiver for converting one or all of the first and second RF signals into at least one second signal; and an antenna switching module coupling the first and second antennas to the superheterodyne receiver and the direct conversion receiver for selectively directing the first and second RF signals to the superheterodyne receiver and/ or the direct conversion receiver, depending on an antenna switch control signal indicating a signal quality derived from the first and second analog signals. a first antenna for receiving a first radio frequency, RF, signal; a second antenna for receiving a second RF signal; a superheterodyne receiver for converting one or all of the first and second RF signals into at least one first analog signal; a direct conversion receiver for converting one or all of the first and second RF signals into at least one second signal; and an antenna switching module coupling the first and second antennas to the superheterodyne receiver and the direct conversion receiver for selectively directing the first and second RF signals to the superheterodyne receiver and/ or the direct conversion receiver, depending on an antenna switch control signal indicating a signal quality derived from the first and second analog signals.
Method for fixing a sleeve on a shaft by means of an adhesive bond, the method comprising the steps of: a) applying the adhesive to a cylindrical inner surface of the sleeve and/or to a cylindrical outer surface of the shaft, and subsequently bringing the adhesive to a consistency in which it does not stick; b) joining the sleeve onto the shaft in the desired relative position in which they are to be connected; c) simultaneously with step b) and/or following step b): activating the adhesive such that it bonds the cylindrical inner surface of the sleeve to the cylindrical outer surface of the shaft by producing an adhesive bond, wherein, the bringing of the adhesive to a consistency in which it does not stick, according to step a), is a prior curing of the adhesive such that the adhesive no longer has any adhesive property at room temperature (20°C), wherein, during the activation of the adhesive according to step c), an increase in volume of the adhesive takes place, in that an adhesive to which a chemical or physical expanding agent has been added is used, characterized in that, when it is applied according to step a), the adhesive has two reactive components (A, B), the one component being arranged in a number of capsules and thus separated from the other component, and wherein, during the implementation of step c), the separating effect of the capsules is destroyed such that the component located in the capsules mixes with the other component of the adhesive and a curing reaction between the two components (A, B) can take place, the separating effect of the capsules being destroyed by thermal energy being introduced into the adhesive and/or into the material of the capsule, in particular by induction, after the joining operation according to step b). a) applying the adhesive to a cylindrical inner surface of the sleeve and/or to a cylindrical outer surface of the shaft, and subsequently bringing the adhesive to a consistency in which it does not stick; b) joining the sleeve onto the shaft in the desired relative position in which they are to be connected; c) simultaneously with step b) and/or following step b): activating the adhesive such that it bonds the cylindrical inner surface of the sleeve to the cylindrical outer surface of the shaft by producing an adhesive bond,
A load securing rail for a transport vehicle or transport container comprising an anchorage means receiver of a first type which defines a first anchorage line extending in the longitudinal direction of the load securing rail and comprising an anchorage means receiver of a second type which is different from the first type, with the anchorage means receiver of the second type defining a second anchorage line which extends substantially in parallel with the first anchorage line, characterised in that the load securing rail forms a wall of a substantially rectangular frame section, with at least one latch projection being formed at a lower side of the frame section.
Oligopeptide or polypeptide, characterized in that it comprises an amino acid sequence which is selected from the group consisting of SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 14, SEQ ID NO: 15, SEQ ID NO: 16, SEQ ID NO: 26, SEQ ID NO: 27, SEQ ID NO: 28 and SEQ ID NO: 29.
A garment wearable by an individual using a harness system for a vehicle seat (40, 41), the garment comprising: an inner front layer; an adjacent outer front layer; wherein the outer front layer has a higher compressibility than the inner front layer; and the garment is adapted to receive one or more harness straps of the harness system between the inner front layer and the outer front layer when the one or more harness straps are routed from the shoulder region (36a, 36b) to a waist region of the garment, and when so routed, the one or more harness straps lie flush against at least a chest area of the inner front layer; comprising an inner collar corresponding to at least a posterior region of left and/or right sides of the individual's neck; an outer collar (28a, 28b) corresponding to at least an anterior region of left and/or right sides of an individual's neck; characterized by the inner collar overlapping with the outer collar (28a, 28b) on left and/or right sides of the individual's neck so as to form left and/or right channels (30a, 30b) for respectively receiving the one or two harness straps routed over left and/or right shoulder regions of the individual. an inner front layer; an adjacent outer front layer; wherein the outer front layer has a higher compressibility than the inner front layer; and the garment is adapted to receive one or more harness straps of the harness system between the inner front layer and the outer front layer when the one or more harness straps are routed from the shoulder region (36a, 36b) to a waist region of the garment, and when so routed, the one or more harness straps lie flush against at least a chest area of the inner front layer; comprising an inner collar corresponding to at least a posterior region of left and/or right sides of the individual's neck; an outer collar (28a, 28b) corresponding to at least an anterior region of left and/or right sides of an individual's neck; characterized by the inner collar overlapping with the outer collar (28a, 28b) on left and/or right sides of the individual's neck so as to form left and/or right channels (30a, 30b) for respectively receiving the one or two harness straps routed over left and/or right shoulder regions of the individual.
Hydroelectric power station for the generation of electrical energy from hydroelectric power - with at least one inlet pipe for supplying a motive water flow to the hydroelectric power station, - with at least one outlet pipe for discharging an outlet water flow, - with at least one water turbine for driving a generator to produce electrical energy, - with at least one water tank, wherein the water tank comprises an outlet and an inlet, - with at least one ejector, - with at least one water loop circuit, - wherein the at least one water turbine, the at least one water tank and the at least one ejector are fluidically connected by the at least one water loop circuit, - wherein the at least one inlet pipe is fluidically connected to the at least one ejector, - wherein the at least one outlet pipe is fluidically connected to the at least one water loop circuit, - wherein the at least one water loop circuit is configured to guide a circulating water flow from the at least one water tank, alongside the at least one ejector, through the at least one water turbine back into the at least one water tank, - wherein the at least one ejector in particular is configured to at least partly suck the circulating water flow from the at least one water tank, - wherein the at least one inlet pipe is configured to provide the motive water flow to the at least one water loop circuit through the at least one ejector, - wherein the current of the motive water flow substantially corresponds to the current of the outlet water flow and - wherein the at least one ejector is located at the outlet of the at least one water tank. - with at least one inlet pipe for supplying a motive water flow to the hydroelectric power station, - with at least one outlet pipe for discharging an outlet water flow, - with at least one water turbine for driving a generator to produce electrical energy, - with at least one water tank, wherein the water tank comprises an outlet and an inlet, - with at least one ejector, - with at least one water loop circuit, - wherein the at least one water turbine, the at least one water tank and the at least one ejector are fluidically connected by the at least one water loop circuit, - wherein the at least one inlet pipe is fluidically connected to the at least one ejector, - wherein the at least one outlet pipe is fluidically connected to the at least one water loop circuit, - wherein the at least one water loop circuit is configured to guide a circulating water flow from the at least one water tank, alongside the at least one ejector, through the at least one water turbine back into the at least one water tank, - wherein the at least one ejector in particular is configured to at least partly suck the circulating water flow from the at least one water tank, - wherein the at least one inlet pipe is configured to provide the motive water flow to the at least one water loop circuit through the at least one ejector, - wherein the current of the motive water flow substantially corresponds to the current of the outlet water flow and - wherein the at least one ejector is located at the outlet of the at least one water tank.
An electronic device, comprising: a UICC in which a first profile is installed; an eUICC; and a processor configured to be electrically connected with the UICC and the eUICC, wherein the processor is configured to: identify that a location of the electronic device corresponds to a country code of a first international mobile station identity, IMSI, included in the first profile; transmit, in response to the identifying, a request for a second profile to be installed in the eUICC from a mobile network operator, MNO, server based on the first profile, the request including information of the first profile; perform authentication with a second server associated with the MNO server; receive the second profile from the second server; and install the received second profile in the eUICC, wherein the first profile includes a first mobile station subscriber directory number, MSISDN, and wherein the second profile includes a second IMSI different from the first IMSI and a second MSISDN identical to the first MSISDN and wherein the second server is a Subscription Manager Data Preparation+ server, SM-DP+ a UICC in which a first profile is installed; an eUICC; and a processor configured to be electrically connected with the UICC and the eUICC, wherein the processor is configured to: identify that a location of the electronic device corresponds to a country code of a first international mobile station identity, IMSI, included in the first profile; transmit, in response to the identifying, a request for a second profile to be installed in the eUICC from a mobile network operator, MNO, server based on the first profile, the request including information of the first profile; perform authentication with a second server associated with the MNO server; receive the second profile from the second server; and install the received second profile in the eUICC, identify that a location of the electronic device corresponds to a country code of a first international mobile station identity, IMSI, included in the first profile; transmit, in response to the identifying, a request for a second profile to be installed in the eUICC from a mobile network operator, MNO, server based on the first profile, the request including information of the first profile; perform authentication with a second server associated with the MNO server; receive the second profile from the second server; and install the received second profile in the eUICC, wherein the first profile includes a first mobile station subscriber directory number, MSISDN, and wherein the second profile includes a second IMSI different from the first IMSI and a second MSISDN identical to the first MSISDN and wherein the second server is a Subscription Manager Data Preparation+ server, SM-DP+
A flexible timepiece component (6, 7) for an oscillator mechanism or for a barrel of a horological movement, the timepiece component (6, 7) including at least a part made of a composite material, wherein the composite material comprises a matrix and a multitude of nanowires distributed in the matrix, the matrix having an overall flat shape extending substantially in a plane, the nanowires being juxtaposed, the matrix including a material for filling the interstices between the nanowires to join them to each other, each nanowire forming a solid one-piece tube, the nanowires being disposed substantially parallel to an axis substantially perpendicular to the plane.
A delivery system for a vascular graft modular assembly comprising an endoprosthetic device which comprises a tubular main body having a length including proximal and distal portions (11, 13), the tubular main body having a flexible portion between the proximal and distal portions, and at least one adjustable length docking branch extending laterally from the tubular main body, and a tubular branch body having a length including proximal and distal stented portions (39, 41), the tubular branch body having a flexible portion between the proximal and distal stented portions (39, 41), and configured to connect with a docking branch of the endoprosthetic device to form the vascular graft modular assembly, the delivery system comprising a sheath for confining the tubular branch body in a compact form for delivery through a lumen, the delivery system being characterised by a retrieval capsule and a press-fit retrieval pin configured to fit within the retrieval capsule, and a retrieval wire having a proximal end and a distal end, wherein one of the retrieval capsule and a press-fit retrieval pin is attached to the sheath and the other is attached to the distal end of the retrieval wire, the proximal end of the retrieval wire being available to a user of the system.
A method for controlling at least one tintable window, the method comprising: receiving sensor readings from one or more sensors associated with a facility; providing the sensor readings to at least one machine learning model configured to determine a forecast of an environmental condition of the facility at a future time; determining a tint state of the at least one tintable window of the facility based at least in part on the forecast of the environmental condition; and providing instructions to transition the at least one tintable window to the tint state determined; the method characterised in that the future time is based at least in part on a duration of time for the at least one tintable window to transition to the tint state determined from a present time. receiving sensor readings from one or more sensors associated with a facility; providing the sensor readings to at least one machine learning model configured to determine a forecast of an environmental condition of the facility at a future time; determining a tint state of the at least one tintable window of the facility based at least in part on the forecast of the environmental condition; and providing instructions to transition the at least one tintable window to the tint state determined; the method characterised in that the future time is based at least in part on a duration of time for the at least one tintable window to transition to the tint state determined from a present time.
A hydrocracking process for treating a first heavy hydrocarbon feedstream and a second heavy hydrocarbon feedstream, the first heavy hydrocarbon feedstream contains undesired nitrogen-containing compounds and poly-nuclear aromatic compounds, the process comprising: a. contacting the first heavy hydrocarbon feedstream with an effective amount of adsorbent material to produce an adsorbent-treated heavy hydrocarbon stream having a reduced content of nitrogen-containing and poly-nuclear aromatic compounds; b. combining the second heavy hydrocarbon feedstream with the adsorbent-treated heavy hydrocarbon stream; c. introducing the combined stream and an effective amount of hydrogen into a hydrocracking reaction unit that contains an effective amount of hydrocracking catalyst to produce a hydrocracked effluent stream; d. fractionating the remainder of the hydrocracked effluent stream to recover hydrocracked products and a bottoms stream containing heavy poly-nuclear aromatic compounds; e. contacting the fractionator bottoms stream with an effective amount of adsorbent material to produce an adsorbent-treated fractionator bottoms stream having a reduced content of heavy poly-nuclear aromatic compounds; f. integrating the adsorbent-treated fractionator bottoms stream with the combined stream of step (b); and g. introducing the combined stream into the hydrocracking reaction unit. a. contacting the first heavy hydrocarbon feedstream with an effective amount of adsorbent material to produce an adsorbent-treated heavy hydrocarbon stream having a reduced content of nitrogen-containing and poly-nuclear aromatic compounds; b. combining the second heavy hydrocarbon feedstream with the adsorbent-treated heavy hydrocarbon stream; c. introducing the combined stream and an effective amount of hydrogen into a hydrocracking reaction unit that contains an effective amount of hydrocracking catalyst to produce a hydrocracked effluent stream; d. fractionating the remainder of the hydrocracked effluent stream to recover hydrocracked products and a bottoms stream containing heavy poly-nuclear aromatic compounds; e. contacting the fractionator bottoms stream with an effective amount of adsorbent material to produce an adsorbent-treated fractionator bottoms stream having a reduced content of heavy poly-nuclear aromatic compounds; f. integrating the adsorbent-treated fractionator bottoms stream with the combined stream of step (b); and g. introducing the combined stream into the hydrocracking reaction unit.
A method to prepare a functionalized DCPD-based resin composition comprising contacting a polymer comprising units derived from DCPD with a vinyl monomer or vinylene monomer, wherein the vinyl monomer or vinylene monomer is represented by one of the following formulae: wherein, each X is, independently, -SiR 2 R 3 R 4, -O-SiR 2 R 3 R 4, or -Si(OR 2)(OR 3)(OR 4); each R 2, R 3, and R 4 is, independently, a hydrogen, a C 1 to C 20 alkyl group, or an aromatic group; each R 1 is, independently, a hydrogen atom or a C 1 to C 40 alkyl group; each Ar is, independently, an aromatic group; and each n is, independently, from 0 to 40. each X is, independently, -SiR 2 R 3 R 4, -O-SiR 2 R 3 R 4, or -Si(OR 2)(OR 3)(OR 4); each R 2, R 3, and R 4 is, independently, a hydrogen, a C 1 to C 20 alkyl group, or an aromatic group; each R 1 is, independently, a hydrogen atom or a C 1 to C 40 alkyl group; each Ar is, independently, an aromatic group; and each n is, independently, from 0 to 40.
A hockey-stick blade extending from a heel section to a toe section, comprising: a core including a top edge, a bottom edge, a heel-end edge, and a toe-end edge; a reinforcing frame having a top portion running along at least a portion of the top edge, a toe portion running along the toe-end edge, and a bottom portion running along at least a portion of the bottom edge, the toe portion of the reinforcing frame having a larger cross-section than at least one of the top or bottom portions of the reinforcing frame; a front-facing wall attached to or integral with at least one of the reinforcing frame and the core; and a rear-facing wall attached to or integral with at least one of the reinforcing frame and the core. a core including a top edge, a bottom edge, a heel-end edge, and a toe-end edge; a reinforcing frame having a top portion running along at least a portion of the top edge, a toe portion running along the toe-end edge, and a bottom portion running along at least a portion of the bottom edge, the toe portion of the reinforcing frame having a larger cross-section than at least one of the top or bottom portions of the reinforcing frame; a front-facing wall attached to or integral with at least one of the reinforcing frame and the core; and a rear-facing wall attached to or integral with at least one of the reinforcing frame and the core.