mhurhangee/ep-ind-claims huggingface dataset:
A compound of Formula I: or pharmaceutically acceptable salts, solvates, or hydrates, thereof, wherein: each R 1 is independently H, alkyl substituted with 1-3 independent R 4; each R 2 is independently alkyl substituted with 1-3 independent R 4; or R 1 and R 2 taken together with the nitrogen atom to which they are attached form a heterocycloalkyl ring having 1, 2, or 3 heteroatoms selected from N, O, and S, wherein the heterocycloalkyl ring may be optionally substituted with 1-3 independent R 4; each R 3 is independently alkyl, alkoxy, amino, halo, C R 5, C 0R 5, SR 5, or NR 5 R 6; each R 4 is independently alkoxy, or aryl optionally substituted with 1-3 independent R 7; each R 5 is independently H, or alkyl; each R 6 is independently H, or alkyl; each R 7 is independently alkyl, alkoxy, amino, halo, C R 5, C 0R 5, SR 5, S 2 R 5, S 2 NR 5 R 6, or NR 5 R 6; n is 0, 1, 2, 3, or 4; and m is 1, 2, 3, or 4 for use as a medicament. each R 1 is independently H, alkyl substituted with 1-3 independent R 4; each R 2 is independently alkyl substituted with 1-3 independent R 4; or R 1 and R 2 taken together with the nitrogen atom to which they are attached form a heterocycloalkyl ring having 1, 2, or 3 heteroatoms selected from N, O, and S, wherein the heterocycloalkyl ring may be optionally substituted with 1-3 independent R 4; each R 3 is independently alkyl, alkoxy, amino, halo, C R 5, C 0R 5, SR 5, or NR 5 R 6; each R 4 is independently alkoxy, or aryl optionally substituted with 1-3 independent R 7; each R 5 is independently H, or alkyl; each R 6 is independently H, or alkyl; each R 7 is independently alkyl, alkoxy, amino, halo, C R 5, C 0R 5, SR 5, S 2 R 5, S 2 NR 5 R 6, or NR 5 R 6; n is 0, 1, 2, 3, or 4; and m is 1, 2, 3, or 4 for use as a medicament.
A multilayer cathode comprising: (a) a conductive layer, the conductive layer being electrically connected as a bus; (b) a layer comprising at least one source of alkali metal ions, alkaline earth metal ions, or lanthanide ions of the formula M n X m; and (c) a conductive metal layer comprising at least one conductive metal species, wherein M is independently at each occurrence an alkali metal ion, an alkaline earth metal ion, or a lanthanide metal ion, wherein X is independently at each occurrence an anion selected from the group consisting of hydroxide, sulfide, selenide, telluride, sulfite, bisulfite, sulfate, bisulfate, phosphite, hydrogenphosphite, phosphate, hydrogenphosphate, nitrite, perchlorate, perchlorite, BF 4 -, PF6 -, phosphonate, sulfonate, boronate, carbonate, bicarbonate, and organic carboxylate, wherein n and m are independently integers from 1 to about 20; wherein the multilayer cathode additionally comprises: (b') an additional layer comprising at least one source of alkali metal ions, alkaline earth metal ions, or lanthanide ions of the formula M n X m, and at least one conductive metal, the conductive metal being the same or different as the conductive metal species of the conductive metal layer; and wherein the source of alkali metal ions, alkaline earth metal ions, or lanthanide ions present in the layer and in the additional layer are the same or different, wherein the layer is positioned between the conductive layer and the conductive metal layer and the additional layer is positioned between the conductive metal layer and the layer. (a) a conductive layer, the conductive layer being electrically connected as a bus; (b) a layer comprising at least one source of alkali metal ions, alkaline earth metal ions, or lanthanide ions of the formula M n X m; and (c) a conductive metal layer comprising at least one conductive metal species,
Field litter support of the type comprising: - two side structures (2, 3) defining a frame, each structure supporting at least one wheel, - hooking devices (38a, 38b, 38c, 38d) for attaching a litter to said frame,- at least two front and/or back (29, 30) foldable bucks (27, 28) fixable to said side structures (2, 3), each of said hooking devices (38a, 38b, 38c, 38d)comprising - two tubular elements (42a, 42b, 42c, 42c, 42d,43a 43b, 43c, 43d) parallelly and specularly located one on the other, connected one to the other in order to form a vice; transversally oriented with respect to the side structures (2,3), - a hooked arm (52a, 52b, 52c, 52d) hinged to the outer end of the lower element (43a, 43b, 43c, 43d) of said tubular elements (42a, 42b, 42c, 42d, 43a, 43b, 43c, 43d) around which said hooked arm (52a, 52b, 52c, 52d) can rotate and cover two main operative positions for respectively hooking and releasing the litter 100, the field litter support characterized by the fact that it comprises means integral with said side structures (2, 3), which enable to reciprocally move close or away the side structures (2, 3) themselves along the axis of said wheels without disassembling said wheels. - two side structures (2, 3) defining a frame, each structure supporting at least one wheel, - hooking devices (38a, 38b, 38c, 38d) for attaching a litter to said frame,- at least two front and/or back (29, 30) foldable bucks (27, 28) fixable to said side structures (2, 3), each of said hooking devices (38a, 38b, 38c, 38d)comprising - two tubular elements (42a, 42b, 42c, 42c, 42d,43a 43b, 43c, 43d) parallelly and specularly located one on the other, connected one to the other in order to form a vice; transversally oriented with respect to the side structures (2,3), - a hooked arm (52a, 52b, 52c, 52d) hinged to the outer end of the lower element (43a, 43b, 43c, 43d) of said tubular elements (42a, 42b, 42c, 42d, 43a, 43b, 43c, 43d) around which said hooked arm (52a, 52b, 52c, 52d) can rotate and cover two main operative positions for respectively hooking and releasing the litter 100, the field litter support characterized by the fact that it comprises means integral with said side structures (2, 3), which enable to reciprocally move close or away the side structures (2, 3) themselves along the axis of said wheels without disassembling said wheels.
A benzoxazole compound represented by the general formula: {wherein R 1 represents a halo (C 1 -C 3) alkoxy group; a halo (C 1 -C 3) alkylsulfinyl group; or a halo (C 1 -C 3) alkylsulfonyl group, R 2 represents a hydrogen atom or a cyano group, and m represents 0;1; or 2}, wherein a benzoxazole compound wherein R 1 is SCF 3 and R 2 is hydrogen is excluded, or a salt thereof. R 1 represents a halo (C 1 -C 3) alkoxy group; a halo (C 1 -C 3) alkylsulfinyl group; or a halo (C 1 -C 3) alkylsulfonyl group, R 2 represents a hydrogen atom or a cyano group, and m represents 0;1; or 2},
A coated substrate, comprising: a substrate defining a surface; and an environmental barrier coating on the surface of the substrate, wherein the environmental barrier coating comprises a barrier layer having a refractory material phase and a silicon-containing glass phase, wherein the silicon-containing glass phase is a continuous phase, wherein the barrier layer comprises Ln 2 SiO 5 where Ln is a rare earth element or a mixture of rare earth elements doped at the Ln site with a dopant, Ln 2 Si 2 O 7 where Ln is a rare earth element or a mixture of rare earth elements doped at the Ln site with the dopant, or a mixture thereof; and wherein the dopant comprises an alkali metal cation, Cu 1+, a noble metal cation, an alkaline earth metal cation, Cu 2+, Ni 2+, Mn 2+, Zn 2+, Sn 2+, or a mixture thereof, and further wherein the dopant has a greater atomic percentage in the silicon-containing glass phase than in the rare earth silicate material of the refractory material phase. a substrate defining a surface; and an environmental barrier coating on the surface of the substrate, wherein the environmental barrier coating comprises a barrier layer having a refractory material phase and a silicon-containing glass phase, wherein the silicon-containing glass phase is a continuous phase, wherein the barrier layer comprises Ln 2 SiO 5 where Ln is a rare earth element or a mixture of rare earth elements doped at the Ln site with a dopant, Ln 2 Si 2 O 7 where Ln is a rare earth element or a mixture of rare earth elements doped at the Ln site with the dopant, or a mixture thereof; and wherein the dopant comprises an alkali metal cation, Cu 1+, a noble metal cation, an alkaline earth metal cation, Cu 2+, Ni 2+, Mn 2+, Zn 2+, Sn 2+, or a mixture thereof, and further wherein the dopant has a greater atomic percentage in the silicon-containing glass phase than in the rare earth silicate material of the refractory material phase.
A sensor configured to find a hidden element behind a surface, the sensor comprising: a housing comprising a top section and a bottom section that is configured to pass over a surface when in use, wherein the bottom section comprises a radiant indicator in a front portion of the bottom section; circuitry coupled to the housing, wherein the circuitry comprises a light chamber having a light surface, a light source and an opening, wherein the circuitry is configured to illuminate the radiant indicator by activating the light source a display positioned in the housing and coupled to the circuitry; and characterized in that the sensor further comprises: a lens assembly coupled to the housing, wherein the lens assembly comprises a lens configured to optically connect the first beam to the radiant indicator, and wherein the lens assembly is insertable into the bottom section; wherein the top section includes an opaque material, and the front of the bottom section is translucent and has a backing, positioned at its bottom side, to reflect light from the light source; wherein the light chamber is configured to reflect light from the light surface to the opening in the light chamber to form a first beam; and wherein the radiant indicator is positioned to receive the first beam. a housing comprising a top section and a bottom section that is configured to pass over a surface when in use, wherein the bottom section comprises a radiant indicator in a front portion of the bottom section; circuitry coupled to the housing, wherein the circuitry comprises a light chamber having a light surface, a light source and an opening, wherein the circuitry is configured to illuminate the radiant indicator by activating the light source a display positioned in the housing and coupled to the circuitry; and characterized in that the sensor further comprises: a lens assembly coupled to the housing, wherein the lens assembly comprises a lens configured to optically connect the first beam to the radiant indicator, and wherein the lens assembly is insertable into the bottom section; wherein the top section includes an opaque material, and the front of the bottom section is translucent and has a backing, positioned at its bottom side, to reflect light from the light source; wherein the light chamber is configured to reflect light from the light surface to the opening in the light chamber to form a first beam; and wherein the radiant indicator is positioned to receive the first beam.
A process for the synthesis of a bioceramic composition for biomedical applications and comprising calcium phosphosilicate (CPS, Ca 10 (PO 4) 4 (SiO 4) 2), wherein the calcium phosphosilicate is present in amount of 50 wt.% or more, wherein the secondary phase(s) comprise(s): (a) hydroxyapatite; or (b) one or more of one or more of alpha-tricalcium phosphate, an alpha-tricalcium phosphate phase, beta-tricalcium phosphate and/or a beta-tricalcium phosphate phase; or (c) (i) hydroxyapatite; and one or both of (ii) alpha-tricalcium phosphate and/or alpha-tricalcium phosphate phase; and/or (iii) beta-tricalcium phosphate and/or beta-tricalcium phosphate phase, the process comprising: providing calcium or a calcium-containing compound, a phosphorus-containing compound and a silicon-containing compound; forming a precipitate by reacting the compounds in an aqueous phase at an alkali pH; and heating the precipitate at a temperature of from 1000 to 1600 °C for from 1 to 120 hours. (a) hydroxyapatite; or (b) one or more of one or more of alpha-tricalcium phosphate, an alpha-tricalcium phosphate phase, beta-tricalcium phosphate and/or a beta-tricalcium phosphate phase; or (c) (i) hydroxyapatite; and one or both of (ii) alpha-tricalcium phosphate and/or alpha-tricalcium phosphate phase; and/or (iii) beta-tricalcium phosphate and/or beta-tricalcium phosphate phase, providing calcium or a calcium-containing compound, a phosphorus-containing compound and a silicon-containing compound; forming a precipitate by reacting the compounds in an aqueous phase at an alkali pH; and heating the precipitate at a temperature of from 1000 to 1600 °C for from 1 to 120 hours.
Hammering device for influencing subsurfaces of workpieces with (a) a beating tool for acting on the workpiece, (b) a beating mechanism that comprises a beater for generating a beating pulse on the beating tool and (c) a drive for driving the beating mechanism, (d) wherein the beating mechanism has at least a second beater for generating a beating pulse on the beating tool, characterised by the fact that (e) the beating mechanism comprises - a drive shaft that extends along a drive axis, and - a wobble ring for transforming a rotational movement of the drive shaft into a translational movement, and (f) the first beater (20.1) and the second beater (20.2) are driven by the wobble ring. (a) a beating tool for acting on the workpiece, (b) a beating mechanism that comprises a beater for generating a beating pulse on the beating tool and (c) a drive for driving the beating mechanism, (d) wherein the beating mechanism has at least a second beater for generating a beating pulse on the beating tool, (e) the beating mechanism comprises - a drive shaft that extends along a drive axis, and - a wobble ring for transforming a rotational movement of the drive shaft into a translational movement, and - a drive shaft that extends along a drive axis, and - a wobble ring for transforming a rotational movement of the drive shaft into a translational movement, (f) the first beater (20.1) and the second beater (20.2) are driven by the wobble ring.
An electronic device, comprising: a first housing structure; a second housing structure; and a hinge structure configured to connect the first and second housing structures (210, 30), the hinge structure comprising: a metallic bracket including a first conductive part, a second conductive part, a first cylindrical through hole, and a second cylindrical through hole; a first cylindrical insulating bushing at least partially positioned inside the first through hole; a second cylindrical insulating bushing at least partially positioned inside the second through hole, wherein the second cylindrical insulating bushing is disposed in parallel and apart from the first cylindrical insulating bushing; a first conductive shaft contacting the first conductive part and extending through the first insulating bushing; a second conductive shaft contacting the second conductive part and extending through the second insulating bushing; and a conductive connector contacting the first conductive shaft and the second conductive shaft and configured to form an electrical path from the first conductive part to the second conductive part through the first conductive shaft, the conductive connector, and the second conductive shaft. a first housing structure; a second housing structure; and a hinge structure configured to connect the first and second housing structures (210, 30), the hinge structure comprising: a metallic bracket including a first conductive part, a second conductive part, a first cylindrical through hole, and a second cylindrical through hole; a first cylindrical insulating bushing at least partially positioned inside the first through hole; a second cylindrical insulating bushing at least partially positioned inside the second through hole, wherein the second cylindrical insulating bushing is disposed in parallel and apart from the first cylindrical insulating bushing; a first conductive shaft contacting the first conductive part and extending through the first insulating bushing; a second conductive shaft contacting the second conductive part and extending through the second insulating bushing; and a conductive connector contacting the first conductive shaft and the second conductive shaft and configured to form an electrical path from the first conductive part to the second conductive part through the first conductive shaft, the conductive connector, and the second conductive shaft.
A method for producing an organic electroluminescent device by providing a lamination structure comprising: an anode electrode layer; a cathode electrode layer opposed to the anode electrode layer; and layers provided between the anode electrode layer and the cathode electrode layer, said layers including a hole injection layer provided adjacent to the anode electrode layer and an organic structure including at least one light-emissive layer or at least one light-emissive unit having at least one light-emissive layer; wherein at least one of the anode electrode layer and the cathode electrode layer is transparent; characterized in that the hole injection layer includes a mixed layer of metal oxide and an organic compound; wherein the mixed layer is formed upon co-deposition of the metal oxide and the organic compound; and wherein the metal oxide is vaporized with one of a resistive heating vapor deposition method, an electron beam vapor deposition method and a laser beam vapor deposition method. an anode electrode layer; a cathode electrode layer opposed to the anode electrode layer; and layers provided between the anode electrode layer and the cathode electrode layer, said layers including a hole injection layer provided adjacent to the anode electrode layer and an organic structure including at least one light-emissive layer or at least one light-emissive unit having at least one light-emissive layer; wherein at least one of the anode electrode layer and the cathode electrode layer is transparent;
Method for setting an outlet pressure (Pout) of a combustion gas volumetric flow at an outlet of a gas valve for a combustion system, in particular for a gas burner, in which air and combustion gas are premixed and the outlet pressure (Pout) of the combustion gas, before entering into a mixing space, is set equal to a reference pressure (Pref), wherein the outlet pressure (Pout) of the combustion gas is set in two stages, and wherein, in a first stage, a pressure (Pi) prevailing on the inlet side is reduced, characterized in that, in the first step, the pressure (Pi) prevailing on the inlet side is reduced to the reference pressure (Pref) plus a predetermined pressure fraction (Px).
A method of phase imaging, comprising: providing a source of X-rays; directing the source of X-rays to define at least one X-ray beam with opposed first and second edges; passing the at least one X-ray beam through a sample region of a sample onto an X-ray detector having pixels or rows of pixels corresponding to the at least one X-ray beam; obtaining a first image in a first configuration wherein the at least one X-ray beam includes at least one first X-ray beam where the first edge of each first X-ray beam overlaps a corresponding pixel or row of pixels in the X-ray detector, but where the second edge of each first X-ray beam does not overlap said pixel or row of pixels, and obtaining a second image in a second configuration wherein the at least one X-ray beam includes at least one second X-ray beam wherein the second edge of each second X-ray beam overlaps a corresponding pixel or row of pixels in the X-ray detector, but where the first edge of each X-ray beam does not overlap said pixel or row of pixels to obtain a second X-ray image; and obtaining a phase image from the first and second X-ray images by taking the difference between the first and second X-ray images. providing a source of X-rays; directing the source of X-rays to define at least one X-ray beam with opposed first and second edges; passing the at least one X-ray beam through a sample region of a sample onto an X-ray detector having pixels or rows of pixels corresponding to the at least one X-ray beam; obtaining a first image in a first configuration wherein the at least one X-ray beam includes at least one first X-ray beam where the first edge of each first X-ray beam overlaps a corresponding pixel or row of pixels in the X-ray detector, but where the second edge of each first X-ray beam does not overlap said pixel or row of pixels, and obtaining a second image in a second configuration wherein the at least one X-ray beam includes at least one second X-ray beam wherein the second edge of each second X-ray beam overlaps a corresponding pixel or row of pixels in the X-ray detector, but where the first edge of each X-ray beam does not overlap said pixel or row of pixels to obtain a second X-ray image; and obtaining a phase image from the first and second X-ray images by taking the difference between the first and second X-ray images.
An antibody which is capable of specific binding to Lymphocyte antigen 75 for use in treatment of pancreatic cancer wherein said antibody contains or is conjugated to a therapeutic moiety.
A cardiographic apparatus comprising: a cardiograph (12, 12") for connection with a plurality of electrodes to acquire cardiographic data; and a respiratory gate (20, 22, 26, 50, 52, 54) configured to identify end-expiration periods, wherein each end-expiration period is detected in a respiratory waveform, by identifying the end-expiration periods based on inflection points of the respiratory waveform so that each of the identified end-expiration periods is temporally preceded by an expiration period of the respiratory waveform and temporally succeeded by an inspiration period of the respiratory waveform, and the respiratory gate (20, 22, 26, 50, 52, 54) is further configured to generate a cardiographic dataset limited to the identified end-expiration periods from cardiographic data acquired by the cardiograph at least during the identified end-expiration periods, by means of a signal processing component (50, 52, 54) that selects portions of acquired cardiographic data corresponding with the identified end-expiration periods to define the cardiographic dataset, wherein the respiratory gate (20, 22, 26, 36, 46, 50, 52, 54) includes: a signal processing component that receives cardiographic data acquired by the cardiograph (12, 12', 12") and identifies end-expiration periods therefrom. a cardiograph (12, 12") for connection with a plurality of electrodes to acquire cardiographic data; and a respiratory gate (20, 22, 26, 50, 52, 54) configured to identify end-expiration periods, wherein each end-expiration period is detected in a respiratory waveform, by identifying the end-expiration periods based on inflection points of the respiratory waveform so that each of the identified end-expiration periods is temporally preceded by an expiration period of the respiratory waveform and temporally succeeded by an inspiration period of the respiratory waveform, and the respiratory gate (20, 22, 26, 50, 52, 54) is further configured to generate a cardiographic dataset limited to the identified end-expiration periods from cardiographic data acquired by the cardiograph at least during the identified end-expiration periods, by means of a signal processing component (50, 52, 54) that selects portions of acquired cardiographic data corresponding with the identified end-expiration periods to define the cardiographic dataset, wherein the respiratory gate (20, 22, 26, 36, 46, 50, 52, 54) includes: a signal processing component that receives cardiographic data acquired by the cardiograph (12, 12', 12") and identifies end-expiration periods therefrom.
Flat-jet nozzle with a mouthpiece having an outlet-orifice and an outlet-chamber with a cross section tapering downstream to the outlet-orifice and a jet shaper characterized in that the jet shaper is designated as a disc having a central opening and further openings surrounding the central opening in a star-shaped rotation-symmetric arrangement, the cross section of the further openings decreasing from the outside inwards.