mhurhangee/ep-ind-claims huggingface dataset:
Crystalline Form 2 of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid (Compound A) having the following structure: (Compound A, Form 2), and characterized by having an X-ray powder diffractogram comprising a peak at 19.3 ±0.2 °2θ, as determined on a diffractogram using Cu-Kα radiation; and (i) the diffractogram further comprises at least one peak selected from 8.1, 10.6, 11.5, 14.5, 16.2, 21.5, 21.9, 22.7, 24.5, and 26.6 °2θ ± 0.2 °2θ, as determined on a diffractogram using Cu-Kα radiation, or (ii) a differential scanning calorimetry curve that comprises an endotherm at about 249 °C, when measured at a heating rate of 10°C/min. (i) the diffractogram further comprises at least one peak selected from 8.1, 10.6, 11.5, 14.5, 16.2, 21.5, 21.9, 22.7, 24.5, and 26.6 °2θ ± 0.2 °2θ, as determined on a diffractogram using Cu-Kα radiation, or (ii) a differential scanning calorimetry curve that comprises an endotherm at about 249 °C, when measured at a heating rate of 10°C/min.
An article of footwear comprising: a sole structure having a bladder element that includes multiple fluid-filled tubes substantially decoupled from one another along their respective lengths; wherein the tubes extend lengthwise at least partially from a lateral extremity of the sole structure to a medial extremity of the sole structure; the bladder element further includes sub-chambers, wherein each of the sub-chambers extends along one of either the lateral extremity or the medial extremity of the sole structure and is connected to end portions of adjacent ones of the tubes, establishing fluid communication at the end portions between the adjacent ones of the tubes; and wherein the sub-chambers are taller in profile than the fluid-filled tubes. a sole structure having a bladder element that includes multiple fluid-filled tubes substantially decoupled from one another along their respective lengths; wherein the tubes extend lengthwise at least partially from a lateral extremity of the sole structure to a medial extremity of the sole structure; the bladder element further includes sub-chambers, wherein each of the sub-chambers extends along one of either the lateral extremity or the medial extremity of the sole structure and is connected to end portions of adjacent ones of the tubes, establishing fluid communication at the end portions between the adjacent ones of the tubes; and wherein the sub-chambers are taller in profile than the fluid-filled tubes.
A machine suitable for processing machining sludge with a view to making briquettes comprises a frame that receives a vessel designed to receive machining sludge to be processed, a helical worm screw mechanism for conveying the material, which mechanism is controlled by a motor, a support platform receiving horizontal and parallel support blocks spaced apart from each other to define a horizontal corridor enabling a slide controlled by an actuator to move in translation, the machine having on one side of the blocks a receive and discharge zone for receiving and discharging compacted briquettes and on the opposite side a collection reservoir receptacle for collecting the lubrication and cutting fluids coming from forming and compacting the briquette, characterized in that said slide is arranged to receive on its top face or on its bottom face a bearing and compression plate arranged with a plurality of channels (17.1) for allowing the cutting fluid to be discharged, and in that the compression plate has a circular central zone (17.1) corresponding to the portion for bearing against the briquette and all around said central zone circular and directed channels (17.2) for enabling the fluid coming from the compression to be discharged, and in that the channels are established in the thickness of the plate and are directed to discharge the fluid into a reservoir block, and in that the machine comprises a vertical thrust actuator suitable or compacting the material in chambers formed below or above the slide and receiving the material to be compacted, and in that the blocks are arranged with vertical openings (8.1) (9.1) in alignment so as to enable the material and the pistons of the actuators and to pass and flow through them.
A method for screening a medicine or a therapeutic target for treating Alzheimer's disease, the method comprising: determining if the medicine or a regulation of the therapeutic target is capable of increasing Aβ secretion from cells, wherein, if the medicine or the regulation of the therapeutic target increases Aβ secretion from cells, then the medicine or the regulation of the therapeutic target can be used to treat Alzheimer's disease.
A semiconductor wafer metrology method comprising: controlling the temperature of a semiconductor wafer to be within a predetermined measurement temperature range by: causing a first change in the temperature of the semiconductor wafer using a first temperature changing unit; and subsequently causing a second change in the temperature of the semiconductor wafer using a second temperature changing unit; wherein the second temperature changing unit comprises a thermal transfer plate that is provided on an outer surface of a weighing chamber of a semiconductor wafer weighing apparatus and that is thermally coupled to, or integral to, the outer surface of the weighing chamber, so that the thermal transfer plate is substantially in thermal equilibrium with the weighing chamber and has substantially the same temperature as the weighing chamber, wherein the semiconductor wafer is positioned on the thermal transfer plate to cause the second change in the temperature of the semiconductor wafer; wherein the magnitude of the first change is greater than the magnitude of the second change; and the method comprises subsequently loading the semiconductor wafer on to a weighing balance of the semiconductor wafer weighing apparatus located within the weighing chamber of the semiconductor wafer weighing apparatus. causing a first change in the temperature of the semiconductor wafer using a first temperature changing unit; and subsequently causing a second change in the temperature of the semiconductor wafer using a second temperature changing unit; wherein the second temperature changing unit comprises a thermal transfer plate that is provided on an outer surface of a weighing chamber of a semiconductor wafer weighing apparatus and that is thermally coupled to, or integral to, the outer surface of the weighing chamber, so that the thermal transfer plate is substantially in thermal equilibrium with the weighing chamber and has substantially the same temperature as the weighing chamber, wherein the semiconductor wafer is positioned on the thermal transfer plate to cause the second change in the temperature of the semiconductor wafer; wherein the magnitude of the first change is greater than the magnitude of the second change; and the method comprises subsequently loading the semiconductor wafer on to a weighing balance of the semiconductor wafer weighing apparatus located within the weighing chamber of the semiconductor wafer weighing apparatus.
Metal-plastic composite profile comprising: - an inner profile made of metal; - an outer profile made of metal; and - an insulating profile made of plastic; wherein - the insulating profile has a geometry which comprises at least one transverse element (9a; 9b, 9c; 14) extending perpendicular to the direction of transverse tensile force; characterised in that the metal-plastic composite profile comprises - a shear-resistant form-locking connection in the direction of transverse tensile force between the insulating profile and the inner profile and - a form-locking connection in the direction of transverse tensile force between the insulating profile and the outer profile and a sliding connection in the direction of thrust; so that - the metal-plastic-composite profile exhibits a reduced deformation in the event of temperature differences between interior and exterior; wherein the material of the insulating profile has a modulus of elasticity of at least 10 GPa, preferably at least 20 GPa and particularly preferably at least 40 GPa, in order to increase the bending stiffness of the metal-plastic composite profile. - an inner profile made of metal; - an outer profile made of metal; and - an insulating profile made of plastic; - the insulating profile has a geometry which comprises at least one transverse element (9a; 9b, 9c; 14) extending perpendicular to the direction of transverse tensile force; - a shear-resistant form-locking connection in the direction of transverse tensile force between the insulating profile and the inner profile and - a form-locking connection in the direction of transverse tensile force between the insulating profile and the outer profile and a sliding connection in the direction of thrust; so that - the metal-plastic-composite profile exhibits a reduced deformation in the event of temperature differences between interior and exterior; wherein
A vibrating member for a vibrating densitometer, comprising: an inner surface including: one or more arcuate portions; and characterised in that the inner surface further includes: two or more raised portions, wherein a first of the two or more raised portions comprises a straight portion, and a second of the two or more raised portions comprises a projecting bump, wherein the two or more raised portions are sized and located to increase a frequency separation between a resonant frequency of a desired vibrational drive mode and a resonant frequency of one or more undesired vibrational modes. an inner surface including: one or more arcuate portions; and characterised in that the inner surface further includes: two or more raised portions, wherein a first of the two or more raised portions comprises a straight portion, and a second of the two or more raised portions comprises a projecting bump, wherein the two or more raised portions are sized and located to increase a frequency separation between a resonant frequency of a desired vibrational drive mode and a resonant frequency of one or more undesired vibrational modes. one or more arcuate portions; and characterised in that the inner surface further includes: two or more raised portions, wherein a first of the two or more raised portions comprises a straight portion, and a second of the two or more raised portions comprises a projecting bump, wherein the two or more raised portions are sized and located to increase a frequency separation between a resonant frequency of a desired vibrational drive mode and a resonant frequency of one or more undesired vibrational modes. two or more raised portions, wherein a first of the two or more raised portions comprises a straight portion, and a second of the two or more raised portions comprises a projecting bump, wherein the two or more raised portions are sized and located to increase a frequency separation between a resonant frequency of a desired vibrational drive mode and a resonant frequency of one or more undesired vibrational modes.
Lid made of paper, consisting a lid disc and a lid ring having a longitudinal axis and a circumferential wall extending in the direction of the longitudinal axis and having an inner surface and an outer surface and a first end and a second end, wherein the lid disc and the lid ring are connected to one another in a materially bonded manner, and wherein the lid disc has a planar region (1.1) extending transversely to the longitudinal axis, characterized in that, - on its outer circumference, comprising a U-shaped region (1.2) adjoining the flat region and having a first wall section (1.3) and a second wall section (1.4), which are connected to one another via a third wall section (1.5), and - wherein the lid ring engages with its first end in the U-shaped region (1.2) of the lid disc in such a way that the first wall section (1.3) rests against the inner surface and the second wall section (1.4) rests against the outer surface, and in that the first wall section (1.3) and the second wall section (1.4) of the U-shaped region (1.2) of the lid disc are connected to the first end of the lid ring in a materially bonded manner, and - in that the wall, in its region which engages in the U-shaped region (1.2) of the lid disc, is drawn inwards in the direction towards the longitudinal axis and a shoulder (3.1) is thereby formed below the lid disc. - on its outer circumference, comprising a U-shaped region (1.2) adjoining the flat region and having a first wall section (1.3) and a second wall section (1.4), which are connected to one another via a third wall section (1.5), and - wherein the lid ring engages with its first end in the U-shaped region (1.2) of the lid disc in such a way that the first wall section (1.3) rests against the inner surface and the second wall section (1.4) rests against the outer surface, and in that the first wall section (1.3) and the second wall section (1.4) of the U-shaped region (1.2) of the lid disc are connected to the first end of the lid ring in a materially bonded manner, and - in that the wall, in its region which engages in the U-shaped region (1.2) of the lid disc, is drawn inwards in the direction towards the longitudinal axis and a shoulder (3.1) is thereby formed below the lid disc.
Multilayer body (100, 20, 300, 400) having a carrier and a layer arranged thereon, said layer comprising electrically conductive material in such an arrangement that - at least one information region and at least one background region are provided, wherein the at least one information region on one side and the at least one background region on the other side are galvanically separated from each other, wherein, - in each information region, a first zone (10, 10a, 10b, 10c, 10d) is provided with electrically conductive material, over the entirety of which zone its electrically conductive material is conductively connected, - in each background region, a plurality of second zones (24, 26) is provided with electrically conductive material, wherein the second zones are galvanically separated from one another, characterised in that, - the at least one information region codes a piece of information which is capacitively readable, - the at least one background region does not carry any information which is detectable by capacitive reading, - a background region completely surrounds all information regions, - the electrically conductive material is provided with an average surface coating which varies by less than 25% across all information regions and background regions, - an information region comprises a plurality of first zones (10, 10a, 10b, 10c, 10d) which are galvanically coupled to one another by at least one conductor track and/or at least one first zone (10, 10a, 10b, 10c, 10d) occupies a surface area which is larger than each of the two zones by a factor of at least two. - at least one information region and at least one background region are provided, wherein the at least one information region on one side and the at least one background region on the other side are galvanically separated from each other, wherein, - in each information region, a first zone (10, 10a, 10b, 10c, 10d) is provided with electrically conductive material, over the entirety of which zone its electrically conductive material is conductively connected, - in each background region, a plurality of second zones (24, 26) is provided with electrically conductive material, wherein the second zones are galvanically separated from one another, characterised in that, - the at least one information region codes a piece of information which is capacitively readable, - the at least one background region does not carry any information which is detectable by capacitive reading, - a background region completely surrounds all information regions, - the electrically conductive material is provided with an average surface coating which varies by less than 25% across all information regions and background regions, - an information region comprises a plurality of first zones (10, 10a, 10b, 10c, 10d) which are galvanically coupled to one another by at least one conductor track and/or at least one first zone (10, 10a, 10b, 10c, 10d) occupies a surface area which is larger than each of the two zones by a factor of at least two.
A method of regulating the drying of a web in a dryer by convective and radiative heat transfer, comprising providing in said dryer a plurality of air flotation bars having an infrared light source for emitting electromagnetic energy and a reflector for reflecting electromagnetic energy emitted by said infrared light source, and characterised by regulating the air temperature of the air responsible for said convective heat transfer to a temperature 5.5 to 28°C (10 to 50°F) lower than the maximum thermal rating of the web material.
A display control device for controlling a display of a display unit mounted in a vehicle, including a dedicated middleware configured to execute a dedicated application program dedicated to a vehicle and prepared on the vehicle side, a general purpose middleware configured to execute a general purpose application program delivered from a source outside of the vehicle, and an interface configured to exchange necessary information between the dedicated middleware and the general purpose middleware, the necessary information including a notification of completion of activation of the general purpose middleware from the general purpose middleware to the dedicated middleware, the display control device comprising: an activation device configured to activate the dedicated middleware first on start-up, and configured to activate the general purpose middleware after the dedicated middleware is activated; and a dedicated display control device configured to display, before an activation of the general-purpose middleware is completed by the activation device, a dedicated menu screen enabling a user to activate the dedicated application program on the display unit via the dedicated middleware when the dedicated application program on the dedicated middleware is available. an activation device configured to activate the dedicated middleware first on start-up, and configured to activate the general purpose middleware after the dedicated middleware is activated; and a dedicated display control device configured to display, before an activation of the general-purpose middleware is completed by the activation device, a dedicated menu screen enabling a user to activate the dedicated application program on the display unit via the dedicated middleware when the dedicated application program on the dedicated middleware is available.
An outdoor robotic work tool adapted for a forward travelling direction and comprising an environmental detection system that comprises a set of outer detector transceivers (2a, 2b) and a set of inner detector transceivers (3a, 3b), where the inner detector transceivers (3a, 3b) are positioned between the outer detector transceivers (2a, 2b), where each detector transceiver (2a, 2b; 3a, 3b) is adapted to transmit signals (4a, 4b; 5a, 5b) and to receive reflected signals (6a, 6b, 9) that have been reflected by an object (10, 11), wherein the outer detector transceivers (2a, 2b) are associated with outer coverage main directions (7a, 7b) that are directed at corresponding outer angles (α a, α b) to the forward travelling direction, and the inner detector transceivers (3a, 3b) are associated with inner coverage main directions (8a, 8b) that are directed at corresponding inner angles (β a, β b) to the forward travelling direction, wherein the inner angles (β a, β b) have magnitudes that exceed the magnitudes of the outer angles (α a, α b), and where the inner coverage main directions (8a, 8b) intersect in front of the outdoor robotic work tool in the forward travelling direction, wherein each coverage main direction (7a, 7b; 8a, 8b) is associated with a corresponding transceiver coverage (12a, 12b; 13a, 13b), where a combined rectangular coverage having a certain width (w) is formed in front of the outdoor robotic work tool in the forward travelling direction, where the combined coverage comprises at least two separate transceiver coverages (12a, 12b; 13a, 13b), where the width (w) is equal to or exceeds to a maximum width of the robotic work tool, where said width (w) extends in a direction orthogonal to the forward travelling direction.
An accumulator control device (20, 20a - 20f), comprising: - a first electrical terminal for connection to a local accumulator; - a second electrical terminal connected to the first electrical terminal, for connection to a remote auxiliary electrical power supply device; - a control unit configured to measure at least one parameter of an accumulator connected to the first electrical terminal and/or an environmental parameter; and - a communication interface for connecting the control unit to the remote auxiliary electrical power supply device; wherein the control unit is configured to transmit measured parameter values and/or values calculated from measured parameter values to the remote auxiliary electrical power supply device via the communication interface to control the charging of the accumulator with a charging end voltage set by the auxiliary electrical power supply device and/or the discharging of the accumulator by the auxiliary electrical power supply device in response to the transmitted values. - a first electrical terminal for connection to a local accumulator; - a second electrical terminal connected to the first electrical terminal, for connection to a remote auxiliary electrical power supply device; - a control unit configured to measure at least one parameter of an accumulator connected to the first electrical terminal and/or an environmental parameter; and - a communication interface for connecting the control unit to the remote auxiliary electrical power supply device; wherein
An environmentally sustainable cement composition which comprises a sulfoaluminate clinker in a percentage ranging from 75 to 97.9% by weight with respect to the weight of the cement, preferably from 89 to 94.5%, ferrous sulfate (FeSO 4 nH 2 O) in a percentage ranging from 2 to 20% by weight with respect to the weight of cement, preferably from 5 to 10%, and an accelerating agent of the hydration reaction in a percentage ranging from 0.1 to 5% by weight with respect to the weight of the cement, preferably from 0.5 to 2%.
A pharmaceutical composition, comprising: i) hepatitis B surface antigen (HBsAg), ii) hepatitis B core antigen (HBcAg), iii) CpG oligodeoxynucleotide (CpG-ODN), and iv) a pharmaceutically acceptable carrier, wherein the CpG-ODN sequence is selected from the group consisting of 5'-TCG TTC GTT CGT TCG TTC GTT-3' (SEQ ID NO: 3), 5'-TCG TTC GTT CGT TCG TTC GTT CGT T-3' (SEQ ID NO: 4), and 5'-TCG TCG TCG TCG TCG TCG TCG-3' (SEQ ID NO: 5). i) hepatitis B surface antigen (HBsAg), ii) hepatitis B core antigen (HBcAg), iii) CpG oligodeoxynucleotide (CpG-ODN), and iv) a pharmaceutically acceptable carrier,
A process of screening a population of plants of the genus Plantago for use in increasing the urine volume of an animal, the process including the steps of: a. measuring the DCAD of each of the population of plants; b. selecting one or more of the population of plants having DCAD less than 10 meq/100 g DM. a. measuring the DCAD of each of the population of plants; b. selecting one or more of the population of plants having DCAD less than 10 meq/100 g DM.
A method for obtaining a concrete construction element by additive manufacturing, wherein superposed mortar layers are successively deposited so as to form two wall surfaces (2, 4), opposite one another, so as to form a cavity, as well as a plurality of reinforcement elements (21, 41, 22, 42) each extending from one of the wall surfaces (2, 4) toward the cavity, said construction element being a wall, a wall element or a floor element, characterized in that each reinforcement element is in contact with neither the wall surface opposite to that from which it extends, nor with a reinforcement element extending from the opposite wall surface to that from which it extends.