mhurhangee/ep-ind-claims huggingface dataset:
An isolated uricase comprising an amino acid sequence of position 8 through position 287 of SEQ ID NO: 7, for use in a method of treating a subject in need thereof, wherein 8 mg of uricase is administered to the subject intravenously once every two weeks.
A space-division multiplexing apparatus comprising: a multi-core fiber having multiple cores (13, 16) including a center core; a multiplexing unit configured to multiplex a plurality of signals for communication and a pilot tone for self-homodyne detection, the signals being generated by a light source; a pilot tone guiding unit configured to guide the pilot tone to a first core for self-homodyne detection, the first core being the center core of the multiple cores; a signal guiding unit configured to guide the signals for communication among the signals multiplexed by the multiplexing unit to a respective plurality of second cores for communication, the second cores being among the multiple cores and symmetrically arranged around the center core; and a self-homodyne detection unit configured to detect the pilot tone output from the first core for self-homodyne detection and to perform the self-homodyne detection. a multi-core fiber having multiple cores (13, 16) including a center core; a multiplexing unit configured to multiplex a plurality of signals for communication and a pilot tone for self-homodyne detection, the signals being generated by a light source; a pilot tone guiding unit configured to guide the pilot tone to a first core for self-homodyne detection, the first core being the center core of the multiple cores; a signal guiding unit configured to guide the signals for communication among the signals multiplexed by the multiplexing unit to a respective plurality of second cores for communication, the second cores being among the multiple cores and symmetrically arranged around the center core; and a self-homodyne detection unit configured to detect the pilot tone output from the first core for self-homodyne detection and to perform the self-homodyne detection.
An insertion instrument for an interspinous spacer, comprising: an elongated barrel having a proximal end and a distal end; the distal end configured for engagement with an interspinous spacer; an inner shaft disposed within the barrel and configured to connect to the interspinous spacer; characterised by when the elongated barrel) is locked to an interspinous spacer, rotation or translation of the inner shaft expands the movably extendable elements of the interpsinous spacer to thereby place it into a deployed condition and reversal of the rotation releases the interspinous spacer for a collapsed, undeployed condition, the distal end of the elongated barrel is configured for engagement with the interspinous spacer via a clamping mechanism disposed at the distal end of the barrel comprising two tangs (1428, 1430) configured to releasably lock to the interspinous spacer. an elongated barrel having a proximal end and a distal end; the distal end configured for engagement with an interspinous spacer; an inner shaft disposed within the barrel and configured to connect to the interspinous spacer; characterised by when the elongated barrel) is locked to an interspinous spacer, rotation or translation of the inner shaft expands the movably extendable elements of the interpsinous spacer to thereby place it into a deployed condition and reversal of the rotation releases the interspinous spacer for a collapsed, undeployed condition, the distal end of the elongated barrel is configured for engagement with the interspinous spacer via a clamping mechanism disposed at the distal end of the barrel comprising two tangs (1428, 1430) configured to releasably lock to the interspinous spacer.
A process for the continuous treatment of a salt-containing solution, proceeding in a forced-circulation evaporator in which the lower boiling liquid fractions are evaporated and the salt is crystallized out, wherein the size of the crystals is controlled and the crystals accumulate at the bottom of the evaporator and are withdrawn in the form of a salt turbidity, wherein in flow direction between evaporator container and pump a decanter is installed, characterized in that a fraction of the solution provided for the further treatment outside the forced-circulation evaporator is separated from the suspension delivered in the circulation via the decanter, by retaining the crystals, and is supplied to the further treatment, wherein the decanter is installed in the circulation line in vertical position and is traversed by the suspension from top to bottom, and wherein the decanter consists of a cylindrical container with a conical lid and a conical bottom, in which the supply line immerses down into the cylindrical part of the container, in which in the cylindrical part two funnels (32a, b) arranged one below the other are installed, whose outlet has the same diameter as the supply line and which with the upper edge are circumferentially connected with the inside of the container, and in which on the outside of the supply line immersing into the container and on the outside of the funnels each in the region of 30 to 70% of the side height a circumferential baffle plate (33a, b, c) is attached, whose free edge forms a circumferential gap with the inside of the container, wherein in the region above the baffle plate a pipe conduit port (34a, b, c) each is located for withdrawing the solution largely liberated from crystals at this point.
Method for operation of an amalgam lamp for reduction of the warm-up time, wherein the amalgam lamp comprises a noble gas-filled emitter tube wherein the amalgam in the emitter tube is heated by means of an external energy source, characterised in that an infrared lamp with a gold-plated mirror is used as energy source.
Induction generator (200; 301), comprising a magnet arrangement (204; 304) for generating a permanent magnetic field, an annular coil (206; 306), a spring element (228; 328) and an air duct (212; 312) through which the permanent magnetic field passes, wherein the magnet arrangement (204; 304) comprises a first pole section (208; 308), a second pole section (210; 310) and a magnet (214; 314) which is arranged between the first pole section (208; 308) and the second pole section (210; 310), the coil (206; 306) is connected to the spring element (228; 328) and is arranged in a movable manner in the air duct (212; 312) and the spring element (228; 328) is designed to effect, in response to a deflection of the coil (206; 306), an oscillation movement of the coil (206; 306) in the air duct (212; 312) transversely to a magnetic flux (222; 322) of the permanent magnetic field within the air duct (212; 312), wherein the air duct (212; 312) has a ring shape and is designed to fully receive the annular coil (206; 306), characterized in that the spring element (228; 328) forms an electrical conductor for making electrical contact with the coil (206; 306).
A method of communication among a plurality of terminals (110,120,130,140), by a first terminal, the method comprising: establishing a session with another terminal (120,130,140) of a group, transmitting, to the group, media from the first terminal acting as a floor arbitrator; receiving a floor request message from a second terminal of the group during the transmitting of the media, wherein the floor request message is transmitted from the second terminal to the group; determining, without a centralized server, whether a floor of the first terminal is revoked based on priority information of the first terminal and the second terminal; stopping a transmission of the media in response to the floor of the first terminal being revoked; and transmitting, to the group, a floor granted message for the second terminal, receiving, from the second terminal, media of the second terminal based on the floor granted message, wherein the media of the second terminal, a new floor arbitrator, is transmitted to the group. establishing a session with another terminal (120,130,140) of a group, transmitting, to the group, media from the first terminal acting as a floor arbitrator; receiving a floor request message from a second terminal of the group during the transmitting of the media, wherein the floor request message is transmitted from the second terminal to the group; determining, without a centralized server, whether a floor of the first terminal is revoked based on priority information of the first terminal and the second terminal; stopping a transmission of the media in response to the floor of the first terminal being revoked; and transmitting, to the group, a floor granted message for the second terminal, receiving, from the second terminal, media of the second terminal based on the floor granted message, wherein the media of the second terminal, a new floor arbitrator, is transmitted to the group.
A package (1; 1A) which houses a tobacco product, characterized in that at least a part of a surface includes a region where a water-soluble varnish containing urethane resin and water as major constituents is applied, and a coefficient of friction with stainless steel of the region where the varnish is applied is 0.2 to 0.5.
An electronic device comprising: an enclosure that has an opening formed therein; a switch disposed in the enclosure opposite the opening; a key top member disposed inside the opening; a water sealing member that has a wall part which extends such that a height direction of the wall part coincides with an opening direction of the opening and which seals an inner surface of the opening, an arm part which extends from the wall part to the inner side of the opening and supports the key top member, and a wall part reinforcer provided in the wall part; and a holder member that has a supporting part to support the switch; characterised in that: the holder member has an extending part which extends from the supporting part to an opening side of the enclosure, a lower end of the wall part being fixed to an end of the extending part. an enclosure that has an opening formed therein; a switch disposed in the enclosure opposite the opening; a key top member disposed inside the opening; a water sealing member that has a wall part which extends such that a height direction of the wall part coincides with an opening direction of the opening and which seals an inner surface of the opening, an arm part which extends from the wall part to the inner side of the opening and supports the key top member, and a wall part reinforcer provided in the wall part; and a holder member that has a supporting part to support the switch; characterised in that: the holder member has an extending part which extends from the supporting part to an opening side of the enclosure, a lower end of the wall part being fixed to an end of the extending part. the holder member has an extending part which extends from the supporting part to an opening side of the enclosure, a lower end of the wall part being fixed to an end of the extending part.
Pedal force simulation arrangement having a slide guide, having at least one slide piece arranged in an axially displaceable manner therein, and having a force store arrangement for generating a restoring force on the at least one slide piece, wherein the force store arrangement has at least one force store unit (18, 20), which acts laterally on the slide piece, characterized in that the force store unit engages into the slide piece over the centre line of the slide piece.
Y 2 O 3:RE nanoparticles having a cubic crystal structure, wherein RE is a trivalent rare earth metal ion, which are nanoplatelets, and wherein the D 50 value of the smallest dimension of the nanoparticles is ≥ 0.5 nm and ≤ 10 nm, as measured using transmission electron microscopy.
A fibroblast growth factor heparin-binding analog of formula I: wherein: each X is a peptide chain that comprises a sequence selected from SEQ ID NO: 7, 9, 14-26, and 28-49; R 1 is a single trifunctional amino acid residue or a dipeptide of the formula AA 1 -AA 2 wherein AA 1 and AA1 2 are each an amino acid residue; R 2 is 0 atoms; each R 3 is hydrogen such that the terminal group is NH 2, or is an acyl group with a linear or branched C 1 to C 17 alkyl, aryl, heteroaryl, alkene, alkenyl or aralkyl chain including an N-terminus NH 2, NH 3 +, or NH group or a corresponding acylated derivative; R 4 is not present if R 1 is a single trifunctional amino acid residue and other wise is independently R 3; R 5 is OH such that the terminal group is a carboxyl, NH 2, an acyl group with a linear or branched C 1 to C 17 alkyl, aryl, heteroaryl, alkene, alkenyl or aralkyl chain including an N-terminus NH 2, NH 3 +, or NH group or a corresponding acylated derivative, or NH-R 3; Y is a linker comprising a chain from 0 to 50 atoms covalently bonded to R 1 and Z; and Z is a non-signaling peptide chain that includes a heparin binding domain, comprising an amino acid sequence that comprises (i) a minimum of one heparin binding motif, (ii) a maximum of ten heparin binding motifs, and (iii) a maximum of thirty amino acids. each X is a peptide chain that comprises a sequence selected from SEQ ID NO: 7, 9, 14-26, and 28-49; R 1 is a single trifunctional amino acid residue or a dipeptide of the formula AA 1 -AA 2 wherein AA 1 and AA1 2 are each an amino acid residue; R 2 is 0 atoms; each R 3 is hydrogen such that the terminal group is NH 2, or is an acyl group with a linear or branched C 1 to C 17 alkyl, aryl, heteroaryl, alkene, alkenyl or aralkyl chain including an N-terminus NH 2, NH 3 +, or NH group or a corresponding acylated derivative; R 4 is not present if R 1 is a single trifunctional amino acid residue and other wise is independently R 3; R 5 is OH such that the terminal group is a carboxyl, NH 2, an acyl group with a linear or branched C 1 to C 17 alkyl, aryl, heteroaryl, alkene, alkenyl or aralkyl chain including an N-terminus NH 2, NH 3 +, or NH group or a corresponding acylated derivative, or NH-R 3; Y is a linker comprising a chain from 0 to 50 atoms covalently bonded to R 1 and Z; and Z is a non-signaling peptide chain that includes a heparin binding domain, comprising an amino acid sequence that comprises (i) a minimum of one heparin binding motif, (ii) a maximum of ten heparin binding motifs, and (iii) a maximum of thirty amino acids.
A method for producing a three-dimensional body, comprising the steps of: a. printing on special paper with an inkjet printer, laser printer or matrix printer, b. Repeating the printing step until all sectional views of a three-dimensional body are present on the special paper at a given layer thickness, c. arranging all the printed special papers obtained in b.) in a suitable arrangement, d. bonding the special papers arranged in this way, e. detaching the obtained three-dimensional body from unbonded special paper, the special paper comprising the following properties: a. activatable bonding tendency with an adjacent layer of a special paper, b. modifiable detachment tendency by printing with a medium, c. bonding ability of the special papers to each other due to activation in the areas defined by printing, d. solubility of the unbonded special paper by the action of a suitable solvent, heat or/and mechanical energy, wherein water-soluble polyvinyl alcohol is used in the special paper and the base material of the special paper is selected from the materials plastic, metal, rock, mineral or ceramic. a. printing on special paper with an inkjet printer, laser printer or matrix printer, b. Repeating the printing step until all sectional views of a three-dimensional body are present on the special paper at a given layer thickness, c. arranging all the printed special papers obtained in b.) in a suitable arrangement, d. bonding the special papers arranged in this way, e. detaching the obtained three-dimensional body from unbonded special paper, the special paper comprising the following properties: a. activatable bonding tendency with an adjacent layer of a special paper, b. modifiable detachment tendency by printing with a medium, c. bonding ability of the special papers to each other due to activation in the areas defined by printing, d. solubility of the unbonded special paper by the action of a suitable solvent, heat or/and mechanical energy, wherein water-soluble polyvinyl alcohol is used in the special paper and the base material of the special paper is selected from the materials plastic, metal, rock, mineral or ceramic. a. activatable bonding tendency with an adjacent layer of a special paper, b. modifiable detachment tendency by printing with a medium, c. bonding ability of the special papers to each other due to activation in the areas defined by printing, d. solubility of the unbonded special paper by the action of a suitable solvent, heat or/and mechanical energy, wherein water-soluble polyvinyl alcohol is used in the special paper and the base material of the special paper is selected from the materials plastic, metal, rock, mineral or ceramic.
A thermally curable ink-jet ink comprising: a compound having a thermally curable functional group; a gelling agent; a compound having a photopolymerizable functional group; and a photopolymerization initiator, wherein the thermally curable ink-jet ink undergoes a sol-gel phase transition depending on temperature, and wherein the compound having a thermally curable functional group is (a) a polyfunctional isocyanate compound having an isocyanate group protected by a thermally dissociable blocking agent, or (b) a (meth)acrylate compound having an imide group. a compound having a thermally curable functional group; a gelling agent; a compound having a photopolymerizable functional group; and a photopolymerization initiator, wherein the thermally curable ink-jet ink undergoes a sol-gel phase transition depending on temperature, and wherein the compound having a thermally curable functional group is (a) a polyfunctional isocyanate compound having an isocyanate group protected by a thermally dissociable blocking agent, or (b) a (meth)acrylate compound having an imide group.
A pharmaceutical composition comprising: 100 mg or 200 mg of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxo1-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1) Form I and a solid dispersion comprising substantially amorphous N-(5-hydroxy-2,4-ditert-butylphenyl)-4-oxo-1H-quinoline-3-carboxamide (Compound 2) and a polymer, wherein the substantially amorphous Compound 2 is present in the pharmaceutical composition in an amount of 125 mg, wherein Compound 1 Form I is characterized by one or more peaks at 15.4, 16.3, and 14.5 degrees in an X-ray powder diffraction pattern, and wherein substantially amorphous Compound 2 has less than 15% crystallinity. 100 mg or 200 mg of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxo1-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1) Form I and a solid dispersion comprising substantially amorphous N-(5-hydroxy-2,4-ditert-butylphenyl)-4-oxo-1H-quinoline-3-carboxamide (Compound 2) and a polymer, wherein the substantially amorphous Compound 2 is present in the pharmaceutical composition in an amount of 125 mg, wherein Compound 1 Form I is characterized by one or more peaks at 15.4, 16.3, and 14.5 degrees in an X-ray powder diffraction pattern, and wherein substantially amorphous Compound 2 has less than 15% crystallinity.
A measurement device comprising: a measurement unit including a first mode that measures an electrical resistance of a recording medium used in an image forming apparatus in a first predetermined range of electrical resistance values and a second mode that measures the electrical resistance in a second range of electrical resistance values different from the first range, the second range and the first range being set such that with respect to the electrical resistance of a plurality of brands of recording media, a number of brands belonging to the second range is greater than a number of brands belonging to the first range; and a control unit (80, 81, 81B) that controls the measurement unit to prioritize execution of the second mode over the first mode. a measurement unit including a first mode that measures an electrical resistance of a recording medium used in an image forming apparatus in a first predetermined range of electrical resistance values and a second mode that measures the electrical resistance in a second range of electrical resistance values different from the first range, the second range and the first range being set such that with respect to the electrical resistance of a plurality of brands of recording media, a number of brands belonging to the second range is greater than a number of brands belonging to the first range; and a control unit (80, 81, 81B) that controls the measurement unit to prioritize execution of the second mode over the first mode.
A switch, in particular a battery cutout switch for vehicles and the like, comprising: - a housing carrying at least one pair of fixed electrical contacts, - a contact-holder body carrying at least one movable electrical contact and movable between an open contacts position and a closed contacts position, and - a handle rotatable relative to the housing about a longitudinal axis between an insertion/extraction position in which the handle can be removed from the housing with a movement in the direction of said longitudinal axis, an open position corresponding to the open contacts position of the contact-holder body, and a closed position corresponding to the closed contacts position of said contact-holder body, wherein the handle is constrained axially with respect to the housing in any position different from the insertion/extraction position, characterized in that it comprises a stop member attachable to the handle in a removable handle position or in a non-removable handle position, the stop member having a first and a second abutment element (80, 82), which cooperate with abutment surfaces (86, 88) of a fixed abutment element to form the stroke-end of the angular movement of the handle, wherein when the stop member is attached to the handle in the removable handle position, the handle is rotatable relative to the housing between the insertion/extraction position, the open position and the closed position, and when the stop member is attached to the handle in the non-removable handle position, the stop member limits the angular movement of the handle between the open position and the closed position. - a housing carrying at least one pair of fixed electrical contacts, - a contact-holder body carrying at least one movable electrical contact and movable between an open contacts position and a closed contacts position, and - a handle rotatable relative to the housing about a longitudinal axis between an insertion/extraction position in which the handle can be removed from the housing with a movement in the direction of said longitudinal axis, an open position corresponding to the open contacts position of the contact-holder body, and a closed position corresponding to the closed contacts position of said contact-holder body, wherein the handle is constrained axially with respect to the housing in any position different from the insertion/extraction position,