A compound of formula in which: R 1 represents hydrogen, C 1 -C 6 -alkyl or C 1 -C 6 -haloalkyl; R 2 represents hydrogen, C 1 -C 6 -alkyl or C 1 -C 6 -haloalkyl; or R 1 and R 2 together with the carbon atom to which they are attached form a 3- to 6-membered cycloalkyl ring; R 3 represents hydrogen, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, R 11 -C -, R 11 O-C - or phenyl-C 1 -C 3 -alkyl-, wherein said phenyl group is optionally substituted, one or more times, independently of each other, with R 5; R 4 represents hydrogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy-C 2 -C 4 -alkyl-; R A represents hydrogen, hydroxy or C 1 -C 4 -alkyl; R B represents hydrogen; or R B and R 2 together form an additional bond; A represents a group selected from: wherein * indicates the point of attachment of said group with the rest of the molecule and said group is optionally substituted, one or more times, independently of each other, with R 5; R 5 represents hydroxy, halogen, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -haloalkyl or C 1 -C 4 -haloalkoxy; E represents a group selected from: wherein * indicates the point of attachment of said group with the rest of the molecule; R 8 represents, independently of each other, halogen, hydroxy, nitro, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 6 -alkoxy, C 3 -C 6 -cycloalkyl, C 3 -C 6 -halocycloalkyl, R 9 R 10 N-, R 11 -C -NH-, R 11 O-C -NH- or R 9 R 10 N-C -NH-, wherein said C 1 -C 6 -alkoxy is optionally substituted one, two or three times, independently of each other, with halogen and is optionally substituted one time with hydroxy, C 1 -C 4 -alkoxy, R 9 R 10 N-, C 3 -C 6 -cycloalkyl, 4- to 7-membered heterocycloalkyl or phenyl, which is optionally substituted one or more times, independently of each other, with R 5; R 9, R 10 represent, independently of each other, hydrogen, C 1 -C 4 -alkyl, C 3 -C 6 -cycloalkyl, C 1 -C 4 -haloalkyl, C 3 -C 6 -halocycloalkyl or phenyl, wherein said phenyl group is optionally substituted, one or more times, independently of each other, with R 5, or R 9 and R 10 together with the nitrogen atom to which they are attached form a 3- to 6-membered nitrogen containing heterocyclic ring, optionally containing one additional heteroatom or heteroatom containing group selected from O, NH and S, and which may be optionally substituted, one or more times, independently of each other, with R 5; R 11 represents, independently of each other, C 1 -C 4 -alkyl, C 3 -C 6 -cycloalkyl, C 1 -C 4 -haloalkyl or C 3 -C 6 -halocycloalkyl; m represents 0, 1, 2 or 3; n represents 0, 1, or 2; or an N-oxide, a pharmaceutically acceptable salt, a tautomer or a stereoisomer of said compound, or a pharmaceutically acceptable salt of said N-oxide, tautomer or stereoisomer. R 1 represents hydrogen, C 1 -C 6 -alkyl or C 1 -C 6 -haloalkyl; R 2 represents hydrogen, C 1 -C 6 -alkyl or C 1 -C 6 -haloalkyl; or R 1 and R 2 together with the carbon atom to which they are attached form a 3- to 6-membered cycloalkyl ring; R 3 represents hydrogen, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, R 11 -C -, R 11 O-C - or phenyl-C 1 -C 3 -alkyl-, wherein said phenyl group is optionally substituted, one or more times, independently of each other, with R 5; R 4 represents hydrogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy-C 2 -C 4 -alkyl-; R A represents hydrogen, hydroxy or C 1 -C 4 -alkyl; R B represents hydrogen; or R B and R 2 together form an additional bond; A represents a group selected from: wherein * indicates the point of attachment of said group with the rest of the molecule and said group is optionally substituted, one or more times, independently of each other, with R 5; R 5 represents hydroxy, halogen, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -haloalkyl or C 1 -C 4 -haloalkoxy; E represents a group selected from: wherein * indicates the point of attachment of said group with the rest of the molecule; R 8 represents, independently of each other, halogen, hydroxy, nitro, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 6 -alkoxy, C 3 -C 6 -cycloalkyl, C 3 -C 6 -halocycloalkyl, R 9 R 10 N-, R 11 -C -NH-, R 11 O-C -NH- or R 9 R 10 N-C -NH-, wherein said C 1 -C 6 -alkoxy is optionally substituted one, two or three times, independently of each other, with halogen and is optionally substituted one time with hydroxy, C 1 -C 4 -alkoxy, R 9 R 10 N-, C 3 -C 6 -cycloalkyl, 4- to 7-membered heterocycloalkyl or phenyl, which is optionally substituted one or more times, independently of each other, with R 5; R 9, R 10 represent, independently of each other, hydrogen, C 1 -C 4 -alkyl, C 3 -C 6 -cycloalkyl, C 1 -C 4 -haloalkyl, C 3 -C 6 -halocycloalkyl or phenyl, wherein said phenyl group is optionally substituted, one or more times, independently of each other, with R 5, or R 9 and R 10 together with the nitrogen atom to which they are attached form a 3- to 6-membered nitrogen containing heterocyclic ring, optionally containing one additional heteroatom or heteroatom containing group selected from O, NH and S, and which may be optionally substituted, one or more times, independently of each other, with R 5; R 11 represents, independently of each other, C 1 -C 4 -alkyl, C 3 -C 6 -cycloalkyl, C 1 -C 4 -haloalkyl or C 3 -C 6 -halocycloalkyl; m represents 0, 1, 2 or 3; n represents 0, 1, or 2;