An apparatus for endoscopic application of surgical clips to body tissue, the apparatus comprising: a handle portion; an elongated tubular member extending distally from the handle portion and defining a longitudinal axis; at least one surgical clip disposed within the tubular member; a jaw assembly including first and second jaw members (26a,26b) mounted at a distal end of the elongated tubular member, each of the first and second jaw members including a raised element (38a,38b) having an angled camming surface (40a,40b) defining a first angle (β) between the camming surfaces (40a, 40b) of the first and second jaw members (26a, 26b) and the plane defined by the surface of the jaw members (26a, 26b) on which the raised elements (38a, 38b) are disposed, the jaw assembly being movable between a spaced, open position and an approximated, substantially closed position; and a locking cam driver including a top surface and a bifurcated distal end portion having a pair of angled camming surfaces (52a,52b) each defining a second angle (α) between the camming surface (52a, 52b) and the plane defined by the top surface, wherein each angled camming surface of the locking cam driver is substantially complementary of a respective angled camming surface of the jaw assembly, each angled camming surface of the locking cam driver being configured to engage a corresponding angled camming surface of the jaw assembly to move the first and second jaw members from the spaced, open position to the approximated, substantially closed position to thereby form a surgical clip, characterised in that the second angle (α) is different from the first angle (β) to define an offset angled configuration. a handle portion; an elongated tubular member extending distally from the handle portion and defining a longitudinal axis; at least one surgical clip disposed within the tubular member; a jaw assembly including first and second jaw members (26a,26b) mounted at a distal end of the elongated tubular member, each of the first and second jaw members including a raised element (38a,38b) having an angled camming surface (40a,40b) defining a first angle (β) between the camming surfaces (40a, 40b) of the first and second jaw members (26a, 26b) and the plane defined by the surface of the jaw members (26a, 26b) on which the raised elements (38a, 38b) are disposed, the jaw assembly being movable between a spaced, open position and an approximated, substantially closed position; and a locking cam driver including a top surface and a bifurcated distal end portion having a pair of angled camming surfaces (52a,52b) each defining a second angle (α) between the camming surface (52a, 52b) and the plane defined by the top surface, wherein each angled camming surface of the locking cam driver is substantially complementary of a respective angled camming surface of the jaw assembly, each angled camming surface of the locking cam driver being configured to engage a corresponding angled camming surface of the jaw assembly to move the first and second jaw members from the spaced, open position to the approximated, substantially closed position to thereby form a surgical clip, characterised in that the second angle (α) is different from the first angle (β) to define an offset angled configuration.