mhurhangee/ep-ind-claims huggingface dataset:
Composition comprising at least one of the following compounds: - the protein consisting of the amino acid sequence as set forth in SEQ ID NO: 1, - a protein derived from the protein as set forth in SEQ ID NO:1 by substitution of at least one nucleotide provided that said protein retains ubiquitin ligase activity and/or participates to DNA replication, said protein consisting of the amino acid sequence as set forth in SEQ ID NO: 2-27, - a nucleic acid molecule coding for said proteins, - a compound affecting the expression of said protein, said compound being a small interfering molecule comprising the nucleic acid sequence as set forth in SEQ ID NO: 32 to 55, - a compound affecting the activity of said protein, said compound being ∘ a fragment of said protein provided that said fragment retains properties to interact with the origin recognition complex, said fragment consisting of the amino acid sequence SEQ ID NO: 59, SEQ ID NO: 29, SEQ ID NO: 30, SEQ ID NO: 60, SEQ ID NO: 61, SEQ ID NO: 62, SEQ ID NO: 63,SEQ ID NO: 100 or SEQ ID NO: 106, or ∘ a nucleic acid molecule coding for said fragment, a salt or a solvate thereof, possibly in association with a pharmaceutically acceptable carrier, for its use for the treatment or the prevention of a human or animal pathology linked to the DNA replication. - the protein consisting of the amino acid sequence as set forth in SEQ ID NO: 1, - a protein derived from the protein as set forth in SEQ ID NO:1 by substitution of at least one nucleotide provided that said protein retains ubiquitin ligase activity and/or participates to DNA replication, said protein consisting of the amino acid sequence as set forth in SEQ ID NO: 2-27, - a nucleic acid molecule coding for said proteins, - a compound affecting the expression of said protein, said compound being a small interfering molecule comprising the nucleic acid sequence as set forth in SEQ ID NO: 32 to 55, - a compound affecting the activity of said protein, said compound being ∘ a fragment of said protein provided that said fragment retains properties to interact with the origin recognition complex, said fragment consisting of the amino acid sequence SEQ ID NO: 59, SEQ ID NO: 29, SEQ ID NO: 30, SEQ ID NO: 60, SEQ ID NO: 61, SEQ ID NO: 62, SEQ ID NO: 63,SEQ ID NO: 100 or SEQ ID NO: 106, or ∘ a nucleic acid molecule coding for said fragment, a salt or a solvate thereof, possibly in association with a pharmaceutically acceptable carrier, for its use for the treatment or the prevention of a human or animal pathology linked to the DNA replication. ∘ a fragment of said protein provided that said fragment retains properties to interact with the origin recognition complex, said fragment consisting of the amino acid sequence SEQ ID NO: 59, SEQ ID NO: 29, SEQ ID NO: 30, SEQ ID NO: 60, SEQ ID NO: 61, SEQ ID NO: 62, SEQ ID NO: 63,SEQ ID NO: 100 or SEQ ID NO: 106, or ∘ a nucleic acid molecule coding for said fragment,
A liquid measuring device comprising: a rotatory body; and a supply path (12A, 12B, 12C) provided in the rotatory body, the supply path including: a liquid receiving section provided in the rotatory body so as to receive a liquid from an outside; and a suction passage provided in communication with the liquid receiving section and configured to suck the liquid in the liquid receiving section by capillary action so as to be filled by the liquid over an entire length thereof, characterized in that the suction passage has a first region, a second region, and an air inlet, the first region extending between a midsection of the suction passage and an end of the suction passage and being configured to be filled by the liquid in a specified amount, the second region extending between the midsection and the liquid receiving section, the air inlet is provided at the midsection of the suction passage, the first region extends in a radial direction, the second region forms a sharp angle with the first region, and the suction passage is configured so that the liquid in the first region, which is to be discharged from the end of the suction passage in the specified amount, is separated from the liquid in the second region by centrifugal forces through rotation of the rotatory body. a rotatory body; and a supply path (12A, 12B, 12C) provided in the rotatory body, the supply path including: a liquid receiving section provided in the rotatory body so as to receive a liquid from an outside; and a suction passage provided in communication with the liquid receiving section and configured to suck the liquid in the liquid receiving section by capillary action so as to be filled by the liquid over an entire length thereof, characterized in that a liquid receiving section provided in the rotatory body so as to receive a liquid from an outside; and a suction passage provided in communication with the liquid receiving section and configured to suck the liquid in the liquid receiving section by capillary action so as to be filled by the liquid over an entire length thereof, characterized in that the suction passage has a first region, a second region, and an air inlet, the first region extending between a midsection of the suction passage and an end of the suction passage and being configured to be filled by the liquid in a specified amount, the second region extending between the midsection and the liquid receiving section, the air inlet is provided at the midsection of the suction passage, the first region extends in a radial direction, the second region forms a sharp angle with the first region, and the suction passage is configured so that the liquid in the first region, which is to be discharged from the end of the suction passage in the specified amount, is separated from the liquid in the second region by centrifugal forces through rotation of the rotatory body.
Selector for an on-load tap changer with a diverter switch, comprising - an insulating plate with a first side and a second, opposite side; - a plurality of fixed contacts which extend from the first side through the insulating plate to the second side; - a first moved contact on the first side; - a first connection, which is connected with the first moved contact and which can be connected with a first branch of the diverter switch; and characterized by, - a second moved contact on the second side; - a second connection, which is connected with the second moved contact and which can be connected with a second branch of the diverter switch; wherein - each moved contact (21, 31) can be selectably connected with each of the fixed contacts. - an insulating plate with a first side and a second, opposite side; - a plurality of fixed contacts which extend from the first side through the insulating plate to the second side; - a first moved contact on the first side; - a first connection, which is connected with the first moved contact and which can be connected with a first branch of the diverter switch; and - a second moved contact on the second side; - a second connection, which is connected with the second moved contact and which can be connected with a second branch of the diverter switch; - each moved contact (21, 31) can be selectably connected with each of the fixed contacts.
Powder product for the protection of centrifugal casting moulds used for the manufacture of cast iron pipes, characterized in that it comprises a mix of particles of an inoculating alloy which is based on ferro-silicon and particles of a strongly reducing metal that is volatile at the temperature of the liquid cast iron which is selected from the group consisting of magnesium, calcium and magnesium and/or calcium alloys, said alloys containing less than 10% of Fe.
An agricultural baler having a baling chamber, an intake duct leading into the baling chamber and a stuffer mechanism for transferring slice of crop in the intake duct into the baling chamber, wherein the baler comprises a wall segment (100, 101) positioned substantially in line with an inner wall surface (106, 107) of the baler, the wall segment (100, 101) being suspended from the inner wall surface (106, 107) via load measurement means (102, 103, 120, 121) in such a manner that a load parallel to the inner wall (106, 107) is derivable from the load measurement means (102, 103, 120, 121), characterized in that also a load perpendicular to the inner wall (106, 107) is derivable from the load measurement means (102, 103, 120, 121).
An electrochemical cell stack, comprising: a plurality of electrochemical cells, each electrochemical cell comprising: a membrane electrode assembly comprising a cathode catalyst layer, an anode catalyst layer, and a polymer membrane interposed between the cathode catalyst layer and the anode catalyst layer; an anode plate and a cathode plate with the membrane electrode assembly interposed therebetween; and a cathode flow field positioned between the cathode plate and the cathode catalyst layer, wherein the cathode flow field comprises a porous structure having a plurality of pores having an average pore size, wherein the plurality of electrochemical cells includes a first electrochemical cell positioned at a first end of the electrochemical cell stack; characterized in that: the porous structure of the first electrochemical cell has an average pore size greater than an average pore size of the porous structures of the plurality of electrochemical cells; and wherein the porous structure of the first electrochemical cell has a flow resistance less than an average flow resistance of the porous structures of the plurality of electrochemical cells. a plurality of electrochemical cells, each electrochemical cell comprising: a membrane electrode assembly comprising a cathode catalyst layer, an anode catalyst layer, and a polymer membrane interposed between the cathode catalyst layer and the anode catalyst layer; an anode plate and a cathode plate with the membrane electrode assembly interposed therebetween; and a cathode flow field positioned between the cathode plate and the cathode catalyst layer, wherein the cathode flow field comprises a porous structure having a plurality of pores having an average pore size, a membrane electrode assembly comprising a cathode catalyst layer, an anode catalyst layer, and a polymer membrane interposed between the cathode catalyst layer and the anode catalyst layer; an anode plate and a cathode plate with the membrane electrode assembly interposed therebetween; and a cathode flow field positioned between the cathode plate and the cathode catalyst layer, wherein the cathode flow field comprises a porous structure having a plurality of pores having an average pore size, wherein the plurality of electrochemical cells includes a first electrochemical cell positioned at a first end of the electrochemical cell stack; characterized in that: the porous structure of the first electrochemical cell has an average pore size greater than an average pore size of the porous structures of the plurality of electrochemical cells; and wherein the porous structure of the first electrochemical cell has a flow resistance less than an average flow resistance of the porous structures of the plurality of electrochemical cells. the porous structure of the first electrochemical cell has an average pore size greater than an average pore size of the porous structures of the plurality of electrochemical cells; and wherein the porous structure of the first electrochemical cell has a flow resistance less than an average flow resistance of the porous structures of the plurality of electrochemical cells.
A power generating circuit, comprising: a first transistor having a control terminal to which a second control signal is applied and one end to which a first control signal is applied; and a second transistor having a control terminal to which the first control signal is applied and one end to which the second control signal is applied, wherein the other ends of the first transistor and the second transistor are connected to an output terminal. a first transistor having a control terminal to which a second control signal is applied and one end to which a first control signal is applied; and a second transistor having a control terminal to which the first control signal is applied and one end to which the second control signal is applied, wherein the other ends of the first transistor and the second transistor are connected to an output terminal.
A cardiac rhythm management system, comprising: at least one first implantable stimulation device and at least one second implantable stimulation device, wherein the at least one first implantable stimulation device comprises a first detection unit adapted to detect a patient's cardiac rhythm and a first processor adapted to analyze the detected patient's cardiac rhythm and to deliver signals for a first antitachycardia pacing therapy, wherein the at least one second implantable stimulation device comprises a second detection unit (200, 203) adapted to detect the patient's cardiac rhythm and a second processor adapted to analyze the detected patient's cardiac rhythm and to deliver signals for shock therapy or a second antitachycardia pacing therapy, and wherein the first processor is adapted to allow delivery of signals for antitachycardia pacing therapy only if the analysis of the patient's cardiac rhythm within a pre-defined preceding time period A reveals a pre-defined tachycardia criterion A' and an absence of a shock therapy, and/or wherein the second processor is adapted to allow delivery of signals for shock therapy or a second antitachycardia therapy only if the analysis of the patient's cardiac rhythm within a pre-defined preceding time period B reveals a pre-defined tachycardia criterion B' and an absence of a first antitachycardia pacing therapy provided by the at least one first implantable stimulation device. at least one first implantable stimulation device and at least one second implantable stimulation device, wherein the at least one first implantable stimulation device comprises a first detection unit adapted to detect a patient's cardiac rhythm and a first processor adapted to analyze the detected patient's cardiac rhythm and to deliver signals for a first antitachycardia pacing therapy, wherein the at least one second implantable stimulation device comprises a second detection unit (200, 203) adapted to detect the patient's cardiac rhythm and a second processor adapted to analyze the detected patient's cardiac rhythm and to deliver signals for shock therapy or a second antitachycardia pacing therapy, and wherein the first processor is adapted to allow delivery of signals for antitachycardia pacing therapy only if the analysis of the patient's cardiac rhythm within a pre-defined preceding time period A reveals a pre-defined tachycardia criterion A' and an absence of a shock therapy, and/or wherein the second processor is adapted to allow delivery of signals for shock therapy or a second antitachycardia therapy only if the analysis of the patient's cardiac rhythm within a pre-defined preceding time period B reveals a pre-defined tachycardia criterion B' and an absence of a first antitachycardia pacing therapy provided by the at least one first implantable stimulation device.
A process for refining molybdenum-100 metal powders, comprising: oxidizing a commercial-grade Mo-100 metal powder in a solution comprising about 3% to about 40% hydrogen peroxide (H 2 O 2) to produce molybdenum oxide; heating the solution comprising molybdenum oxide and H 2 O 2 to denature excess H 2 O 2; drying the molybdenum oxide; in a first stage in an atmosphere comprising less than about 5% hydrogen, heating the dried molybdenum oxide at temperature from a range of about 300° C to about 500° C for a period of time from a range of about 15 minutes to about 3 hours to form MoO 3; in a second stage in an atmosphere comprising less than about 5% hydrogen, increasing the temperature to a range of about 600° C to about 850° C for a period of time from a range of about 15 minutes to about 3 hours to form MoO 2; in a third stage in an atmosphere comprising at least about 75% hydrogen, increasing the temperature to a range of about 1,000° C to about 1,300° C for a period of time from a range of about 15 minutes to about 3 hours to form a refined Mo-100 metal; and recovering the refined Mo-100 metal. oxidizing a commercial-grade Mo-100 metal powder in a solution comprising about 3% to about 40% hydrogen peroxide (H 2 O 2) to produce molybdenum oxide; heating the solution comprising molybdenum oxide and H 2 O 2 to denature excess H 2 O 2; drying the molybdenum oxide; in a first stage in an atmosphere comprising less than about 5% hydrogen, heating the dried molybdenum oxide at temperature from a range of about 300° C to about 500° C for a period of time from a range of about 15 minutes to about 3 hours to form MoO 3; in a second stage in an atmosphere comprising less than about 5% hydrogen, increasing the temperature to a range of about 600° C to about 850° C for a period of time from a range of about 15 minutes to about 3 hours to form MoO 2; in a third stage in an atmosphere comprising at least about 75% hydrogen, increasing the temperature to a range of about 1,000° C to about 1,300° C for a period of time from a range of about 15 minutes to about 3 hours to form a refined Mo-100 metal; and recovering the refined Mo-100 metal.
A filter assembly, comprising; a filter having a rod extending along an axis with a plate disposed at one end thereof, the plate comprising an opening for facilitating the passage of fluid; a wing disposed on the filter; wherein the difference of the distance between a nearest and a furthest point of the opening and that of the wing from the axis is a first length (x) and a second length (y) respectively; wherein the second length (y) is greater than the first length (x) and wherein the projection of the wing along the axis is configured to surround that of the opening; characterized in that the wing and the opening comprise a pair of end lines perpendicularly extending away from the axis and that the angles subtended by an arc from the end lines of the wing and that arc from the end lines of the opening are α and β respectively, the vertex being the axis, and that the relation between the angles is; α > β + 5 degrees. a filter having a rod extending along an axis with a plate disposed at one end thereof, the plate comprising an opening for facilitating the passage of fluid; a wing disposed on the filter; wherein the difference of the distance between a nearest and a furthest point of the opening and that of the wing from the axis is a first length (x) and a second length (y) respectively; wherein the second length (y) is greater than the first length (x) and wherein the projection of the wing along the axis is configured to surround that of the opening; characterized in that the wing and the opening comprise a pair of end lines perpendicularly extending away from the axis and that the angles subtended by an arc from the end lines of the wing and that arc from the end lines of the opening are α and β respectively, the vertex being the axis, and that the relation between the angles is; α > β + 5 degrees.
A lithographic printing plate precursor comprising an image recording layer containing an infrared absorber represented by Formula I, on a support: in Formula I, each of X 1 and X 2 independently represents a sulfur atom, an oxygen atom, or a dialkylmethylene group having 12 or less carbon atoms, each of Y 1 and Y 2 independently represents a monovalent organic group or a hydrogen atom, each of Z 1 and Z 2 independently represents a benzene ring, a naphthalene ring, or a 6- to 20-membered heteroaromatic ring unsubstituted or substituted with an electron-donating group or an aryl group having from 6 to 20 carbon atoms, each of R 1, R 2, R 3, and R 4 independently represents a hydrogen atom or a hydrocarbon group having 12 or less carbon atoms, each of R 5 and R 6 independently represents a hydrocarbon group which optionally forms a 5-membered ring or a 6-membered ring, each of R 7, R 8, R 9, and R 10 independently represents a hydrogen atom or a monovalent organic group, and A represents a counter ion present in a case in which charge neutralization is needed, wherein the image recording layer further comprises an iodonium-based polymerization initiator.
A method for increasing abiotic stress resistance in plants relative to control plants, comprising increasing expression in a plant of a nucleic acid encoding a SYR polypeptide, which SYR polypeptide comprises a leucine rich domain, preceded by the conserved tripeptide motif 1 according to one of SEQ ID NO: 256, 257, 258 or 259. and followed by the conserved motif 2 according to SEQ ID NO: 260, wherein said increased abiotic stress resistance is increased nutrient uptake efficiency, relative to control plants, wherein said SYR polypeptide has at least 80%, 85%, 90%, 95% or more sequence identity to the SYR polypeptide represented by SEQ ID NO: 252, and wherein said increased expression is effected by introducing and expressing in a plant a nucleic acid encoding said SYR polypeptide.
A rapid exchange type stent delivery catheter (280, 300), comprising: an outer tubular member (290, 314) having a proximal end, a distal end, and a lumen extending therebetween, the outer tubular member (290, 314) having a guidewire entry port (282, 302) disposed closer to the distal end than the proximal end; an inner tubular member (286, 306) extending distally from a location distal of the guidewire entry port (282, 302), the inner tubular member (286, 306) adapted to receive a self-expanding stent thereon, the inner tubular member (286, 306) axially movable relative to the outer tubular member (290, 314) such that, when a stent is disposed on the inner tubular member (286, 306) and the inner tubular member (286, 306) is in a first position, the stent is restrained by the outer tubular member (290, 314), and when the inner tubular member (286, 306) is in a second position, the stent is not restrained by the outer tubular member (290, 314); a mandrel (296, 320) positioned within the outer tubular member (290, 314) and extending in the lumen of the outer tubular member (290, 314) from a location near a proximal end of the outer tubular member (290, 314) to a location proximal of the guidewire entry port (282, 302); and an elongate pushing member (288, 312) attached to the inner tubular member (286, 306) and extending proximally from a location distal of the guidewire entry port (282, 302) to a location proximal of a proximal end of the outer tubular member (290, 314). an outer tubular member (290, 314) having a proximal end, a distal end, and a lumen extending therebetween, the outer tubular member (290, 314) having a guidewire entry port (282, 302) disposed closer to the distal end than the proximal end; an inner tubular member (286, 306) extending distally from a location distal of the guidewire entry port (282, 302), the inner tubular member (286, 306) adapted to receive a self-expanding stent thereon, the inner tubular member (286, 306) axially movable relative to the outer tubular member (290, 314) such that, when a stent is disposed on the inner tubular member (286, 306) and the inner tubular member (286, 306) is in a first position, the stent is restrained by the outer tubular member (290, 314), and when the inner tubular member (286, 306) is in a second position, the stent is not restrained by the outer tubular member (290, 314); a mandrel (296, 320) positioned within the outer tubular member (290, 314) and extending in the lumen of the outer tubular member (290, 314) from a location near a proximal end of the outer tubular member (290, 314) to a location proximal of the guidewire entry port (282, 302); and an elongate pushing member (288, 312) attached to the inner tubular member (286, 306) and extending proximally from a location distal of the guidewire entry port (282, 302) to a location proximal of a proximal end of the outer tubular member (290, 314).
Sulfated hyaluronic acid amides with C4-C20 alkenylamines, said amides having a % molar degree of derivatisation, expressed as alkenylamine mols/HAS dimer mols, ranging from 2 to 20%, preferably 5-15%, more preferably 10%.