A bi-directional perfusion cannula, comprising a flexible elongated tube for insertion into an artery configured to lay longitudinally in the artery, having: a first aperture oriented forward during insertion into an artery at a first end of a distal portion of the elongated tube, said distal portion of the elongated tube being configured to lay longitudinally in the artery, said first aperture being configured so that blood can flow into the artery in a direction of insertion, a second aperture formed rearward of the first aperture at a second end of said distal portion of the elongated tube, and configured to supply blood into the artery in a second direction, said elongated tube being configured to be bent in correspondence of said second aperture in order to orient said second aperture in said second direction opposite to the insertion direction, wherein the bi-directional perfusion cannula comprises: a tape having a first end portion shaped as a ring, fixed on an outer surface of the elongated tube, and a second end portion opposite to the first end portion, said second end portion being either configured to be coupled to or being integral with a belt defining a strap with holes and at least a prong integral with said strap and configured to engage a respective one of said holes, said belt being made of a bio-compatible material and being configured to be tightened around an outer surface of the artery; characterized in that said tape is configured to allow to tighten said belt at a distance from a point of insertion of said elongated tube in the artery, so as to tighten the artery together with the distal portion of the elongated tube when said distal portion of the elongated tube lays longitudinally in the artery. a first aperture oriented forward during insertion into an artery at a first end of a distal portion of the elongated tube, said distal portion of the elongated tube being configured to lay longitudinally in the artery, said first aperture being configured so that blood can flow into the artery in a direction of insertion, a second aperture formed rearward of the first aperture at a second end of said distal portion of the elongated tube, and configured to supply blood into the artery in a second direction, said elongated tube being configured to be bent in correspondence of said second aperture in order to orient said second aperture in said second direction opposite to the insertion direction, wherein the bi-directional perfusion cannula comprises: a tape having a first end portion shaped as a ring, fixed on an outer surface of the elongated tube, and a second end portion opposite to the first end portion, said second end portion being either configured to be coupled to or being integral with a belt defining a strap with holes and at least a prong integral with said strap and configured to engage a respective one of said holes, said belt being made of a bio-compatible material and being configured to be tightened around an outer surface of the artery; characterized in that said tape is configured to allow to tighten said belt at a distance from a point of insertion of said elongated tube in the artery, so as to tighten the artery together with the distal portion of the elongated tube when said distal portion of the elongated tube lays longitudinally in the artery.