A compound of Formula and pharmaceutically acceptable salts, solvates, or solvates of salts thereof, wherein: X is N or C-R 3, Y is NH, O or absent, R 1 is L 1 -R 4 -L 2 -R 5 or L 1 -R 4, R 2 is A, Hal, OH, OA, SH, CN, NH 2, NO 2, NHA, NH-L 1 -Ar, NHCOA, NHCO-L 1 -Ar, NHSO 2 A, NHSO 2 -L 1 -Ar, NHCONHA, NHCONH-L 1 -Ar, L 1 -Ar, O- L 1 -Ar, L 1 -R 4, L 1 is a single bond, methylene, or methyl substituted methylene, wherein the methylene, or the methyl group of the methyl substituted methylene may be unsubstituted or mono- or disubstituted with Hal, OH, CN, NH 2, NH, N 2, NO 2, COOH, N 3, ethenyl or ethynyl, and/or monosubstituted with R 4, and in which one or two CH 2 groups may be replaced by an O or S atom or by an -NH-, -N -, -CONH-, -N COO-, -SO 2 - or -NHCO- group, R 3 is H, A, Hal, OH, COOH, SH, NH 2, NO 2 or CN, R 4, R 5 each, independently of one another, are Ar, or cyclic A which may be mono- or disubstituted by Hal or LA, L 2 is -NHCO-, -NHCOO-, -NHCONH-, -NHCONA-, -NHCOA-, -O-, -S-, -NH-, -NHSO 2 - -SO 2 NH-, -CONH-, -CONHCONH-, -NHCONHCO-, or -A-, Ar is a mono- or bicyclic aromatic homo- or heterocycle having 0, 1, 2, 3 or 4 N, O and/or S atoms and 5, 6, 7, 8, 9, or 10 skeleton atoms, which may be unsubstituted or, independently of one another, mono-, di- or trisubstituted by Hal, A, OH, SH, OA, NH 2, NHA, NA 2, NO 2, CN, OCN, SCN, COOH, COOA, CONH 2, CONHA, CONA 2, NHCOA, NHCONHA, NHCONH 2, NHSO 2 A, CHO, COA, SO 2 NH 2, SO 2 A and/or SO 2 Hal, and in which a ring N-atom may be substituted by an O-atom to form an N-oxide group, and in which in the case of a bicyclic aromatic cycle on of the two rings may be partly saturated, A is unbranched or branched linear or cyclic alkyl having 1, 2, 3, 4, 5, 6, 7 or 8 C atoms, in which one or two CH 2 groups may be replaced by an O or S atom and/or by an -NH-, -CO-, -NHCOO-, -NHCONH-. -N -, -CONH-, -NHCO- or -CH=CH- group, and in which 1-3 H atoms may be replaced by Hal, and in which one or two CH 3 groups may be replaced by OH, SH, NH 2, NH, N 2, NHCOOH, NHCONH 2 or CN, LA is unbranched or branched, linear alkyl having 1, 2, 3 or 4 C atoms, wherein 1, 2 or 3 H atoms may be replaced by Hal, Hal is F, Cl, Br or I. X is N or C-R 3, Y is NH, O or absent, R 1 is L 1 -R 4 -L 2 -R 5 or L 1 -R 4, R 2 is A, Hal, OH, OA, SH, CN, NH 2, NO 2, NHA, NH-L 1 -Ar, NHCOA, NHCO-L 1 -Ar, NHSO 2 A, NHSO 2 -L 1 -Ar, NHCONHA, NHCONH-L 1 -Ar, L 1 -Ar, O- L 1 -Ar, L 1 -R 4, L 1 is a single bond, methylene, or methyl substituted methylene, wherein the methylene, or the methyl group of the methyl substituted methylene may be unsubstituted or mono- or disubstituted with Hal, OH, CN, NH 2, NH, N 2, NO 2, COOH, N 3, ethenyl or ethynyl, and/or monosubstituted with R 4, and in which one or two CH 2 groups may be replaced by an O or S atom or by an -NH-, -N -, -CONH-, -N COO-, -SO 2 - or -NHCO- group, R 3 is H, A, Hal, OH, COOH, SH, NH 2, NO 2 or CN, R 4, R 5 each, independently of one another, are Ar, or cyclic A which may be mono- or disubstituted by Hal or LA, L 2 is -NHCO-, -NHCOO-, -NHCONH-, -NHCONA-, -NHCOA-, -O-, -S-, -NH-, -NHSO 2 - -SO 2 NH-, -CONH-, -CONHCONH-, -NHCONHCO-, or -A-, Ar is a mono- or bicyclic aromatic homo- or heterocycle having 0, 1, 2, 3 or 4 N, O and/or S atoms and 5, 6, 7, 8, 9, or 10 skeleton atoms, which may be unsubstituted or, independently of one another, mono-, di- or trisubstituted by Hal, A, OH, SH, OA, NH 2, NHA, NA 2, NO 2, CN, OCN, SCN, COOH, COOA, CONH 2, CONHA, CONA 2, NHCOA, NHCONHA, NHCONH 2, NHSO 2 A, CHO, COA, SO 2 NH 2, SO 2 A and/or SO 2 Hal, and in which a ring N-atom may be substituted by an O-atom to form an N-oxide group, and in which in the case of a bicyclic aromatic cycle on of the two rings may be partly saturated, A is unbranched or branched linear or cyclic alkyl having 1, 2, 3, 4, 5, 6, 7 or 8 C atoms, in which one or two CH 2 groups may be replaced by an O or S atom and/or by an -NH-, -CO-, -NHCOO-, -NHCONH-. -N -, -CONH-, -NHCO- or -CH=CH- group, and in which 1-3 H atoms may be replaced by Hal, and in which one or two CH 3 groups may be replaced by OH, SH, NH 2, NH, N 2, NHCOOH, NHCONH 2 or CN, LA is unbranched or branched, linear alkyl having 1, 2, 3 or 4 C atoms, wherein 1, 2 or 3 H atoms may be replaced by Hal, Hal is F, Cl, Br or I.