mhurhangee/ep-ind-claims huggingface dataset:
A monoclonal antibody or antibody fragment thereof that specifically binds Tau oligomers having spherical morphology and comprising a protein aggregate of about 3 to 24 Tau polypeptides, which monoclonal antibody or antibody fragment does not bind soluble TAU or TAU fibrils at levels that are detectable above background.
A method of synthesizing a substituted cyclopentenone compound, the method comprising contacting a compound of formula ("compound "): wherein subscript n is 1, 2, 3, or 4; and each of groups R1, R2, R3, and R4 is independently H or (C 1 -C 4)alkyl, or any two adjacent R1 to R3 groups are bonded together to form a (C 1 -C 4)alkylene and the remaining group of R1 to R3 is H or (C 1 -C 4)alkyl, with an effective amount of a phosphorous pentoxide/methanesulfonic acid reagent (P 2 O 5 /H 3 CSO 3 H reagent) and under reaction conditions sufficient to make a compound of formula ("compound "): wherein subscript n and groups R1 to R4 are as defined above; and with the proviso that the contacting step is free of added polyphosphoric acid.
A method of restoring a metallic component, the method comprising: (i) removing material from a region (8, 10) of the component to be restored in a manner which leaves a cavity in a surface of the component; (ii) establishing cavity profile data representing the profile of the cavity surface; (iii) using the cavity profile data to form a first metallic repair insert having a contact surface complementary to the cavity surface; (iv) applying the first repair insert to the component with the contact surface of the first repair insert in contact with the cavity surface; and (v) applying heat to the first repair insert to fuse the contact surface of the first repair insert to the cavity surface; wherein in step (v), the heat is applied to the first repair insert successively at spaced locations on the first repair insert so as to fuse the contact surface of the first repair insert to the cavity surface successively at the respective locations, in which the heated locations overlap one another whereby, following completion of the heat application to all of the heated locations, the contact surface of the first repair insert is fused to the cavity surface over substantially the full area of the contact surface. (i) removing material from a region (8, 10) of the component to be restored in a manner which leaves a cavity in a surface of the component; (ii) establishing cavity profile data representing the profile of the cavity surface; (iii) using the cavity profile data to form a first metallic repair insert having a contact surface complementary to the cavity surface; (iv) applying the first repair insert to the component with the contact surface of the first repair insert in contact with the cavity surface; and (v) applying heat to the first repair insert to fuse the contact surface of the first repair insert to the cavity surface; wherein
A power management unit for an embedded flash memory system, comprising: a first voltage source for providing a first power supply voltage utilized in performing program, erase, and read operations in flash memory cells in the embedded flash memory system; a second voltage source for providing a second power supply voltage utilized by control logic in the embedded flash memory system; wherein during a first time period at the beginning of a power-on sequence, the voltage output (VDD 601, VDDFLASH 603) from the first voltage source ramps upward and the voltage output (VDDCORE 602) from the second voltage source ramps upward; during a second time period immediately following the first time period, the voltage output from the first voltage source ramps upward and the voltage output from the second voltage remains at a constant level; during a third time period immediately following the second time period, the voltage output from the first voltage source ramps upward and the voltage output from the second voltage sour ramps upward; and during a fourth time period immediately following the third time period, the voltage output from the first voltage source ramps upward and the voltage output from the second voltage source remains at a constant level. a first voltage source for providing a first power supply voltage utilized in performing program, erase, and read operations in flash memory cells in the embedded flash memory system; a second voltage source for providing a second power supply voltage utilized by control logic in the embedded flash memory system; wherein during a first time period at the beginning of a power-on sequence, the voltage output (VDD 601, VDDFLASH 603) from the first voltage source ramps upward and the voltage output (VDDCORE 602) from the second voltage source ramps upward; during a second time period immediately following the first time period, the voltage output from the first voltage source ramps upward and the voltage output from the second voltage remains at a constant level; during a third time period immediately following the second time period, the voltage output from the first voltage source ramps upward and the voltage output from the second voltage sour ramps upward; and during a fourth time period immediately following the third time period, the voltage output from the first voltage source ramps upward and the voltage output from the second voltage source remains at a constant level.
Mould for moulding a component, comprising a first nozzle-side and a second ejector-side mould half (1, 2), a mould insert (3, 4) which is inserted into a respective mould half (1, 2), wherein, in the closed state of the mould, the mould inserts (3, 4) delimit a mould cavity of the mould, and the mould inserts (3, 4) are produced from a solidifiable material by additive buildup in layers, and a preferably thermoplastic moulding compound can be injected into the mould cavity, characterized in that a stripping device is provided in the region of the outer circumference of the ejector-side mould insert, the stripping device is produced from a solidifiable material by additive buildup in layers, an axially movable support having a bearing surface which is positioned below the stripping device is provided, and the bearing surface of the support can be varied.
A transport refrigeration system (100, 200), comprising: an undersized main power source configured to generate up to a maximum threshold power that is lower than an amount of power sufficient to run the TRS at a full cooling capacity, wherein the undersized main power source is not capable of supplying a sufficient amount of power by itself to run the TRS at the full cooling capacity; and a secondary power source configured to generate up to the maximum threshold power that is lower than the amount of power sufficient to run the TRS at the full cooling capacity, wherein the secondary power source is not capable of supplying a sufficient amount of power by itself to run the TRS at the full cooling capacity, a tertiary power source; and a controller; wherein the undersized main power source and the secondary power source are configured to cooperate with one another to supply power to the TRS at the full cooling capacity; wherein the controller is configured to determine whether a maximum current is drawn from the secondary power source; and wherein the tertiary power source is configured to supply power to the TRS to supplement the undersized main power source to allow the TRS to operate at the full cooling capacity when the controller determines that the maximum current is drawn from the secondary power source.
A compound of formula ZZ: wherein n = 1 or 2; R, independently of other R, is hydrogen, halogen, allyl, or alkyl group having from 1 to 6 carbon atoms; R 2 = hydrogen, alkyl group having from 1 to 6 carbon atoms, ester; R 3 = hydrogen, halogen, alkyl, haloalkyl, allyl, alkenyl, or haloalkenyl; R 4 and R 5 are N; or R 4 =N and R 5 =C; or R 4 and R 5 = C; and A = oxygen or sulfur; for use in the treatment of cancer, by administering to a patient in need thereof an effective amount of said compound.
A filling machine for filling flexible pouch type packages each having a filling channel and being essentially flat in a non-filled state of the package, the filling machine comprising a transport unit arranged for intermittent, edgewise advancement of the packages in a feeding direction from an upstream station to a downstream station via a filling station, whereby the expression "edgewise advancement" of the package should be construed as movement of the package in a direction coinciding with the plane in which the package in an essentially flat, non-filled state extends, the transport unit being movable along an axis parallel with the feeding direction in a reciprocating manner between a first end position A and a second end position B, the transport unit comprising a first gripping member which, when the transport unit is in the first end position A, is arranged to retrieve one or more of the packages in a non-filled state from the upstream station and which, when the transport unit is in the second end position B, is arranged to deliver the one or more of the packages in the non-filled state to the filling station, the transport unit comprising a second gripping member which, when the transport unit is in the first end position A, is arranged to retrieve one or more of the packages in a filled state from the filling station and which, when the transport unit is in the second end position B, is arranged to deliver the one or more of the packages in the filled state to the downstream station, the machine being characterized in that the transport unit comprises a suction cup member arranged for opening-up of the filling channel of the one or more of the packages in the non-filled state retrieved by the first gripping member while the transport unit is moved from the first end position A to the second end position, wherein the suction cup member for each package retrieved by the first gripping member comprises a pair of oppositely arranged suction cups which are movably arranged in order to engage and separate side wall sections defining the filling channel of the associated package.
An intragastric device, comprising: a shaft; and at least a first balloon fixed to the shaft, the first balloon having a core of a first material and a coating of a second material, the first material comprising polydimethylsiloxane and the second material comprising polydiphenylsiloxane, wherein the core has an inner surface and an outer surface, and wherein the coating is on at least one of the inner surface of the core and the outer surface of the core. a shaft; and at least a first balloon fixed to the shaft, the first balloon having a core of a first material and a coating of a second material, the first material comprising polydimethylsiloxane and the second material comprising polydiphenylsiloxane, wherein the core has an inner surface and an outer surface, and wherein the coating is on at least one of the inner surface of the core and the outer surface of the core.
A method for preparing a liquid feed for feeding livestock by mixing a liquid feed consisting of a plurality of liquid feed components in a mixing container, wherein the liquid feed components comprise a liquid component and milk replacement powder and the method comprises the following steps: • measuring a refractive index of the liquid component and/or the mixed liquid feed by a refractometer and • calculating a quantity of a liquid feed component which is to be added into the mixing container in order to achieve a predetermined dry matter content of the liquid feed, wherein the calculation is carried out by an electronic controller on the basis of the measured refractive index and the controller is connected to the refractometer and the measurement of the refractive index and the calculation take place automatically. • measuring a refractive index of the liquid component and/or the mixed liquid feed by a refractometer and • calculating a quantity of a liquid feed component which is to be added into the mixing container in order to achieve a predetermined dry matter content of the liquid feed, wherein the calculation is carried out by an electronic controller on the basis of the measured refractive index and the controller is connected to the refractometer and the measurement of the refractive index and the calculation take place automatically.
A display apparatus comprising: a display panel comprising a first pixel including a first organic light emitting diode (OLED); and a panel driver configured to perform a black current bypass operation by applying a first voltage to an anode electrode of the first OLED while a first frame image is displayed on the display panel only when a grayscale of the first frame image is lower than a first reference grayscale and a grayscale of a second frame image is higher than a second reference grayscale, wherein the first and second frame images (IMG1, IMG2) are two consecutive images, and wherein the first reference grayscale is between one and two percent of a maximum supported grayscale of the display panel and the second reference grayscale is between ninety-eight and ninety-nine percent of the maximum supported grayscale of the display panel. a display panel comprising a first pixel including a first organic light emitting diode (OLED); and a panel driver configured to perform a black current bypass operation by applying a first voltage to an anode electrode of the first OLED while a first frame image is displayed on the display panel only when a grayscale of the first frame image is lower than a first reference grayscale and a grayscale of a second frame image is higher than a second reference grayscale, wherein the first and second frame images (IMG1, IMG2) are two consecutive images, and wherein the first reference grayscale is between one and two percent of a maximum supported grayscale of the display panel and the second reference grayscale is between ninety-eight and ninety-nine percent of the maximum supported grayscale of the display panel.
Scanning probe nanolithography system comprising a probe to create nanostructures line by line through writing said nanostructures pixel by pixel along lines on a sample, a XYZ positioning system, adapted to provide a positioning of the probe at a sequence of predetermined positions to the sample and its surface towards the probe, a control unit adapted to control the positioning system for positioning the probe for a pixel-wise writing of said lines through a writing unit, comprising a write/actuation mechanism for the creation of the nanostructures, and a sensor unit adapted to detect a predetermined property of the written nanostructure, characterized in that the control unit is adapted to control a XY portion of the positioning system to position the read line that follows the write line in a constant distance in parallel at or between positions of earlier write lines, wherein the sensor unit is connected to the control unit to adapt the control signals to be provided to the writing unit for writing the following line based on the measured signals of the predetermined property, wherein the predetermined property is a physical property based on friction, thermal conductivity, electrical conductivity, electrostatic potential, magnetic moment, adhesion, elastic modulus or topography.
A mobile communication system which applies a High Speed Downlink Packet Access, HSDPA, in a downlink and an enhanced uplink packet transmission scheme in an uplink between a mobile station and a base station, wherein, the mobile station is adapted to perform a serving cell change to a certain cell for the High Speed Downlink Packet Access and the enhanced uplink packet transmission scheme so that the changed serving cell is the same for both the High Speed Downlink Packet Access and the enhanced uplink packet transmission scheme, when a condition for modifying the High Speed Downlink Packet Access serving cell is satisfied.
A polymer blend comprising: at least 90% by weight low density polyethylene (LDPE) polymer, wherein the LDPE polymer has a melt index (I 2) from 2 to 6 g/10 mins as determined in accordance with ASTM D1238 (190 °C, 2.16 kg, Procedure B), and a molecular weight distribution (MWD = Mw/Mn) from 5 to 11 as determined by a conventional gel permeation chromatography method; and from 1 wt.% to 10% by weight ionomer, the ionomer comprising an ethylene acid copolymer having from 15% to 70% of the carboxylic acid groups neutralized as carboxylic acid salts comprising sodium cations based on the total number of acid groups in the polymer, wherein the ethylene acid copolymer is the polymerized reaction product of: at least 50% by wt. ethylene, based on the total wt.% of the monomers present in the ethylene acid copolymer; from 2 wt.% to 30 wt.% of monocarboxylic acid monomer, based on the total wt.% of the monomers present in the ethylene acid copolymer; and from 0 wt.% to 25 wt.% of alkyl acrylate, based on the total wt.% of the monomers present in the ethylene acid copolymer. at least 90% by weight low density polyethylene (LDPE) polymer, wherein the LDPE polymer has a melt index (I 2) from 2 to 6 g/10 mins as determined in accordance with ASTM D1238 (190 °C, 2.16 kg, Procedure B), and a molecular weight distribution (MWD = Mw/Mn) from 5 to 11 as determined by a conventional gel permeation chromatography method; and from 1 wt.% to 10% by weight ionomer, the ionomer comprising an ethylene acid copolymer having from 15% to 70% of the carboxylic acid groups neutralized as carboxylic acid salts comprising sodium cations based on the total number of acid groups in the polymer, wherein the ethylene acid copolymer is the polymerized reaction product of: at least 50% by wt. ethylene, based on the total wt.% of the monomers present in the ethylene acid copolymer; from 2 wt.% to 30 wt.% of monocarboxylic acid monomer, based on the total wt.% of the monomers present in the ethylene acid copolymer; and from 0 wt.% to 25 wt.% of alkyl acrylate, based on the total wt.% of the monomers present in the ethylene acid copolymer. at least 50% by wt. ethylene, based on the total wt.% of the monomers present in the ethylene acid copolymer; from 2 wt.% to 30 wt.% of monocarboxylic acid monomer, based on the total wt.% of the monomers present in the ethylene acid copolymer; and from 0 wt.% to 25 wt.% of alkyl acrylate, based on the total wt.% of the monomers present in the ethylene acid copolymer.
Distance measuring device having a tubular housing, a bushing that closes a first free end of the housing, and a distance sensor which is accommodated in the housing, extends through the bushing, measures in contactless fashion, and is a confocal-chromatic or acoustic distance sensor, characterized in that the distance sensor is accommodated in the housing so as to be able to be moved axially between an operating position in which a tip of the distance sensor projects outward from the bushing of the distance measuring device, and a retracted position in which the tip of the distance sensor is arranged within the bushing of the distance measuring device, and in that the distance measuring device has an arresting device which is designed in such a manner that the distance sensor can be arrested at least in its operating position by manual actuation of the arresting device.
A bartending workstation, comprising a bearing structure, above which a work surface is defined, at least one opening being defined at said work surface inside which opening there is at least one ice-holder tray; at least one bottle-holder tray adjacent to said work surface being defined, said at least one bottle-holder tray being supported by said same bearing structure, and comprising a raised plane, said raised plane being supported by a rising portion included in, that is being part of, said bearing structure, at least said bearing structure being constituted by at least one single piece (420A, 420B) of a sheet or of a plate of a folded self-supporting flexible material, characterized in that: - said bearing structure with said rising portion and said raised plane are made up of two single pieces, first and second, each of a sheet or plate of a folded self-supporting material, joined one to another; - said work surface, with said at least one opening, consists of a third single piece of a sheet or plate of a folded self-supporting material; - said bottle-holder tray consists of a fourth single piece of a sheet or plate of a folded self-supporting material. and comprising a raised plane, said raised plane being supported by a rising portion included in, that is being part of, said bearing structure, at least said bearing structure being constituted by at least one single piece (420A, 420B) of a sheet or of a plate of a folded self-supporting flexible material, characterized in that: - said bearing structure with said rising portion and said raised plane are made up of two single pieces, first and second, each of a sheet or plate of a folded self-supporting material, joined one to another; - said work surface, with said at least one opening, consists of a third single piece of a sheet or plate of a folded self-supporting material; - said bottle-holder tray consists of a fourth single piece of a sheet or plate of a folded self-supporting material. - said bearing structure with said rising portion and said raised plane are made up of two single pieces, first and second, each of a sheet or plate of a folded self-supporting material, joined one to another; - said work surface, with said at least one opening, consists of a third single piece of a sheet or plate of a folded self-supporting material; - said bottle-holder tray consists of a fourth single piece of a sheet or plate of a folded self-supporting material.
A grating device for phase contrast imaging and/or dark-field imaging of a movable object comprising: - a grating unit, - an actuation unit, - a motion detecting unit, and - a control unit, wherein the actuation unit is configured to position the grating unit in different sampling positions relative to the moveable object, wherein the motion detecting unit is configured to detect a motion of the movable object, wherein the control unit is configured to control the actuation unit to position the grating unit in the different sampling positions based on the detected motion of the movable object. - a grating unit, - an actuation unit, - a motion detecting unit, and - a control unit,