A compound having the general Formula: wherein R1 is selected from the group consisting of -H, C 1-6 -alkyl, C 1-6 -alkoxy, C 1-3 -alkoxy-C 1-3 -alkyl, C 1-6 -alkylthio, C 1-3 -alkylthio-C 1-3 -alkyl, C 1-3 -alkylamino-C 1-3 -alkyl, 4- to 10-membered heterocycloalkyl, C 3-10 -cycloalkyl, C 6-10 -aryl, C 6-10 -aryl-C 1-2 -alkyl and 5- to 10-membered heteroaryl, wherein said C 1-6 -alkyl, C 1-6 -alkoxy, C 1-3 -alkoxy-Ci- 3 -alkyl, C 1-6 -alkylthio, C 1-3 -alkylthio-C 1-3 -alkyl, C 1-3 -alkylamino-C 1-3 -alkyl, C 6-10 -aryl, 4- to 10-membered heterocycloalkyl, C 3-10 -cycloalkyl, C 6-10 -aryl-C 1-2 -alkyl and 5- to 10-membered heteroaryl is optionally substituted by one or more groups independently selected from the group consisting of C 1-4 -alkyl, -OH, halogen, -CO-N 2, -N 2, -CO-R4, -COO-R4, -N 3, -NO 2, and -CN; R2 is selected from the group consisting of -CO-R5 and -CONH-R5; R3 is tetrahydropyran-4-yl, which is optionally substituted by one or more groups independently selected from the group consisting of C 1-4 -alkyl, -OH, and halogen; R4 is each independently selected from the group consisting of H and C 1-4 -alkyl; n is an integer from 3 to 6; and R5 is selected from the group consisting of -H, C 1-6 -alkyl, C 1-6 -alkoxy, C 1-3 -alkoxy-C 1-3 -alkyl, C 1-6 -alkylthio, C 1-3 -alkylthio-C 1-3 -alkyl, C 1-3 -alkylamino-C 1-3 -alkyl, C 6-10 -aryl, 4- to 10-membered heterocycloalkyl, C 3-10 -cycloalkyl and 5- to 10-membered heteroaryl, wherein said C 1-6 -alkyl, C 1-6 -alkoxy, C 1-3 -alkoxy-C 1-3 -alkyl, C 1-6 -alkylthio, C 1-3 -alkylthio-C 1-3 -alkyl, C 1-3 -alkylamino-C 1-3 -alkyl, C 6-10 -aryl, 4- to 10-membered heterocycloalkyl, C 3-10 -cycloalkyl and 5- to 10-membered heteroaryl is optionally substituted by one or more groups independently selected from the group consisting of C 1-4 -alkyl, -OH, halogen, -CO-N 2, -N 2, -CO-R4, -COO-R4, -N 3, -NO 2, and -CN; or a solvate or salt thereof, wherein the compound is not tert-butyl [4-(4-amino-2-ethyl-1H-imidazo [4,5-c] quinolin-1-yl) butyl] tetrahydro-2H-pyran-4-ylcarbamate. R1 is selected from the group consisting of -H, C 1-6 -alkyl, C 1-6 -alkoxy, C 1-3 -alkoxy-C 1-3 -alkyl, C 1-6 -alkylthio, C 1-3 -alkylthio-C 1-3 -alkyl, C 1-3 -alkylamino-C 1-3 -alkyl, 4- to 10-membered heterocycloalkyl, C 3-10 -cycloalkyl, C 6-10 -aryl, C 6-10 -aryl-C 1-2 -alkyl and 5- to 10-membered heteroaryl, wherein said C 1-6 -alkyl, C 1-6 -alkoxy, C 1-3 -alkoxy-Ci- 3 -alkyl, C 1-6 -alkylthio, C 1-3 -alkylthio-C 1-3 -alkyl, C 1-3 -alkylamino-C 1-3 -alkyl, C 6-10 -aryl, 4- to 10-membered heterocycloalkyl, C 3-10 -cycloalkyl, C 6-10 -aryl-C 1-2 -alkyl and 5- to 10-membered heteroaryl is optionally substituted by one or more groups independently selected from the group consisting of C 1-4 -alkyl, -OH, halogen, -CO-N 2, -N 2, -CO-R4, -COO-R4, -N 3, -NO 2, and -CN; R2 is selected from the group consisting of -CO-R5 and -CONH-R5; R3 is tetrahydropyran-4-yl, which is optionally substituted by one or more groups independently selected from the group consisting of C 1-4 -alkyl, -OH, and halogen; R4 is each independently selected from the group consisting of H and C 1-4 -alkyl; n is an integer from 3 to 6; and R5 is selected from the group consisting of -H, C 1-6 -alkyl, C 1-6 -alkoxy, C 1-3 -alkoxy-C 1-3 -alkyl, C 1-6 -alkylthio, C 1-3 -alkylthio-C 1-3 -alkyl, C 1-3 -alkylamino-C 1-3 -alkyl, C 6-10 -aryl, 4- to 10-membered heterocycloalkyl, C 3-10 -cycloalkyl and 5- to 10-membered heteroaryl, wherein said C 1-6 -alkyl, C 1-6 -alkoxy, C 1-3 -alkoxy-C 1-3 -alkyl, C 1-6 -alkylthio, C 1-3 -alkylthio-C 1-3 -alkyl, C 1-3 -alkylamino-C 1-3 -alkyl, C 6-10 -aryl, 4- to 10-membered heterocycloalkyl, C 3-10 -cycloalkyl and 5- to 10-membered heteroaryl is optionally substituted by one or more groups independently selected from the group consisting of C 1-4 -alkyl, -OH, halogen, -CO-N 2, -N 2, -CO-R4, -COO-R4, -N 3, -NO 2, and -CN; or a solvate or salt thereof, wherein the compound is not tert-butyl [4-(4-amino-2-ethyl-1H-imidazo [4,5-c] quinolin-1-yl) butyl] tetrahydro-2H-pyran-4-ylcarbamate.