Compounds of formula wherein R 1, R 2, R 3, R 4 and R 5 are independently selected from H, halogen, cyano, nitro, C 1 - 7 -alkyl, halo-C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl, C 1 -C 7 -alkoxy, halo-C 1 -C 7 -alkoxy and C 3 -C 8 -cycloalkoxy; R 6 is H, C 1 -C 7 -alkyl, halo-C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl, substituted aryl or substituted heteroaryl, wherein substituted aryl or substituted heteroaryl are substituted with R 18, R 19 and R 20; R 7, R 8, R 9, R 10, R 11 and R 12 are independently selected from H, halogen, C 1 -C 7 -alkyl and halo-C 1 -C 7 -alkyl; A 1 is -(CR 14 R 15) p -C NR 16 R 17 or -(CR 14 R 15) p -C OR 17; R 14 and R 15 are independently selected from H, C 1 -C 7 -alkyl, halo-C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl and halo-C 3 -C 8 -cycloalkyl; R 16 is H, C 1 -C 7 -alkyl, halo-C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl, hydroxy-C 1 -C 7 -alkyl, C 1 -C 7 -alkoxy-C 1 -C 7 -alkyl or halo-C 1 -C 7 -alkoxy-C 1 -C 7 -alkyl; R 17 is H, C 1 -C 7 -alkyl, halo-C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl, C 3 -C 8 -cycloalkyl-C 1 -C 7 -alkyl, C 1 -C 7 -alkoxy-C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkoxy-C 1 -C 7 -alkyl, substituted aryl or substituted heteroaryl, wherein substituted aryl and substituted heteroaryl are substituted with R 21, R 22 and R 23; or R 16 and R 17 together with the nitrogen to which they are attached form a substituted heterocycloalkyl or a substituted heteroaryl, wherein substituted heterocycloalkyl and substituted heteroaryl are substituted with R 21, R 22 and R 23; R 18, R 19, R 20, R 21, R 22 and R 23 are independently selected from H, halogen, C 1 -C 7 -alkyl, halo-C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl, C 1 -C 7 -alkoxy and halo-C 1 -C 7 -alkoxy; n is zero, 1 or 2; p is zero, 1 or 2; and pharmaceutically acceptable salts thereof. R 1, R 2, R 3, R 4 and R 5 are independently selected from H, halogen, cyano, nitro, C 1 - 7 -alkyl, halo-C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl, C 1 -C 7 -alkoxy, halo-C 1 -C 7 -alkoxy and C 3 -C 8 -cycloalkoxy; R 6 is H, C 1 -C 7 -alkyl, halo-C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl, substituted aryl or substituted heteroaryl, wherein substituted aryl or substituted heteroaryl are substituted with R 18, R 19 and R 20; R 7, R 8, R 9, R 10, R 11 and R 12 are independently selected from H, halogen, C 1 -C 7 -alkyl and halo-C 1 -C 7 -alkyl; A 1 is -(CR 14 R 15) p -C NR 16 R 17 or -(CR 14 R 15) p -C OR 17; R 14 and R 15 are independently selected from H, C 1 -C 7 -alkyl, halo-C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl and halo-C 3 -C 8 -cycloalkyl; R 16 is H, C 1 -C 7 -alkyl, halo-C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl, hydroxy-C 1 -C 7 -alkyl, C 1 -C 7 -alkoxy-C 1 -C 7 -alkyl or halo-C 1 -C 7 -alkoxy-C 1 -C 7 -alkyl; R 17 is H, C 1 -C 7 -alkyl, halo-C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl, C 3 -C 8 -cycloalkyl-C 1 -C 7 -alkyl, C 1 -C 7 -alkoxy-C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkoxy-C 1 -C 7 -alkyl, substituted aryl or substituted heteroaryl, wherein substituted aryl and substituted heteroaryl are substituted with R 21, R 22 and R 23; or R 16 and R 17 together with the nitrogen to which they are attached form a substituted heterocycloalkyl or a substituted heteroaryl, wherein substituted heterocycloalkyl and substituted heteroaryl are substituted with R 21, R 22 and R 23; R 18, R 19, R 20, R 21, R 22 and R 23 are independently selected from H, halogen, C 1 -C 7 -alkyl, halo-C 1 -C 7 -alkyl, C 3 -C 8 -cycloalkyl, C 1 -C 7 -alkoxy and halo-C 1 -C 7 -alkoxy; n is zero, 1 or 2; p is zero, 1 or 2;