A storage device for biological samples, the device comprising: a collection medium having a predetermined size and shape, the collection medium comprising: a top surface; a bottom surface; a position marker, wherein the position marker is a void containing no collection medium, wherein the position marker may be used as a 'home' position where a collection instrument needle resides when blood samples are not collected; a first central void extending through the center of the collection medium; at least one first alignment void, and at least one binding site operable to bind a biological sample; a protective facing (110,180) substantially impermeable to the biological sample, the protective facing coupled to the top surface of the collection medium and having a size and shape substantially similar to the predetermined size and shape of the collection medium, the protective facing including: a second central void in the middle of the protective facing, the second central void structured and positioned so as to align with the first central void; and at least one second alignment void structured and positioned so as to respectively align with the at least one first alignment void in the collection medium; wherein the protective facing is sized and shaped to define a first facing void and a second facing void, the first facing void positioned to allow for the transfer of the biological sample through the protective facing and onto the at least one binding site of the collection medium, the second facing void positioned to expose the position marker. a collection medium having a predetermined size and shape, the collection medium comprising: a top surface; a bottom surface; a position marker, wherein the position marker is a void containing no collection medium, wherein the position marker may be used as a 'home' position where a collection instrument needle resides when blood samples are not collected; a first central void extending through the center of the collection medium; at least one first alignment void, and at least one binding site operable to bind a biological sample; a top surface; a bottom surface; a position marker, wherein the position marker is a void containing no collection medium, wherein the position marker may be used as a 'home' position where a collection instrument needle resides when blood samples are not collected; a first central void extending through the center of the collection medium; at least one first alignment void, and at least one binding site operable to bind a biological sample; a protective facing (110,180) substantially impermeable to the biological sample, the protective facing coupled to the top surface of the collection medium and having a size and shape substantially similar to the predetermined size and shape of the collection medium, the protective facing including: a second central void in the middle of the protective facing, the second central void structured and positioned so as to align with the first central void; and at least one second alignment void structured and positioned so as to respectively align with the at least one first alignment void in the collection medium; a second central void in the middle of the protective facing, the second central void structured and positioned so as to align with the first central void; and at least one second alignment void structured and positioned so as to respectively align with the at least one first alignment void in the collection medium; wherein the protective facing is sized and shaped to define a first facing void and a second facing void, the first facing void positioned to allow for the transfer of the biological sample through the protective facing and onto the at least one binding site of the collection medium, the second facing void positioned to expose the position marker.