mhurhangee/ep-ind-claims huggingface dataset:
A pharmaceutical composition comprising a pharmaceutically acceptable carrier and an isolated antibody or antigen-binding fragment thereof that binds to a free C5a polypeptide, wherein the free C5a is a human polypeptide (hC5a) having the amino acid sequence depicted in SEQ ID NO:1, and wherein the antibody or antigen-binding fragment thereof binds to the free hC5a polypeptide in vitro with a K D that is less than 1.25 x 10 -9 M as measured by surface plasmon resonance in the presence of a molar excess of uncleaved, native human C5; and wherein the antibody or antigen binding fragment thereof comprises a light chain polypeptide comprising: a light chain CDR1 comprising the amino acid sequence depicted in SEQ ID NO: 20; a light chain CDR2 comprising the amino acid sequence depicted in SEQ ID NO: 21; and a light chain CDR3 comprising the amino acid sequence depicted in SEQ ID NO: 22; and further wherein the antibody or antigen binding fragment thereof comprises a heavy chain polypeptide comprising: a heavy chain CDR1 comprising the amino acid sequence depicted in SEQ ID NO: 28; a heavy chain CDR2 comprising the amino acid sequence depicted in SEQ ID NO: 46; and a heavy chain CDR3 comprising the amino acid sequence depicted in SEQ ID NO: 47.
An apparatus for attaching tissue to bone comprising: an expander pin having a longitudinal passageway formed therein, the longitudinal passageway extending the length of the expander pin; and an expandable body having a distal end surface and a proximal end surface, and a central passageway extending from the distal end surface to the proximal end surface configured to receive said expander pin; said expander pin expanding said expandable body when said expander pin is received in said expandable body; and further comprising an installation tool having a shaft sized to be received in said central passageway of the expandable body and in said longitudinal passageway of said expander pin, characterised in that the shaft of the installation tool comprises means for releasably securing to corresponding means on the expandable body. an expander pin having a longitudinal passageway formed therein, the longitudinal passageway extending the length of the expander pin; and an expandable body having a distal end surface and a proximal end surface, and a central passageway extending from the distal end surface to the proximal end surface configured to receive said expander pin; said expander pin expanding said expandable body when said expander pin is received in said expandable body; and further comprising an installation tool having a shaft sized to be received in said central passageway of the expandable body and in said longitudinal passageway of said expander pin, characterised in that the shaft of the installation tool comprises means for releasably securing to corresponding means on the expandable body.
A soluble pharmaceutical formulation comprising an insulin derivative wherein the formulation further comprises a) more than 4 zinc atoms per 6 molecules of the insulin derivative, b) citric acid monohydrate and/or a histidine compound used in an amount from 0.1 mM to 2 mM sufficient to increase the tendency of the insulin derivative to self-associate into dodecamers. a) more than 4 zinc atoms per 6 molecules of the insulin derivative, b) citric acid monohydrate and/or a histidine compound used in an amount from 0.1 mM to 2 mM sufficient to increase the tendency of the insulin derivative to self-associate into dodecamers.
A hoist mechanism for loading into or unloading from a load carrying space of a vehicle, the hoist mechanism being installable in said vehicle and comprising a lifting arm pivotally connected to an actuator, the inclination of said lifting arm being controlled by the actuator, wherein: when the lifting arm is in a fully raised position, a projecting upper end section of a major part of the lifting arm extends substantially horizontally; an effective length of the projecting upper end section is made variable by the provision of an extension element adjustably fixed to it; and characterised in that the lifting arm is variable in upstanding height by a provision of a lower end section slidably connected to the major part of the lifting arm, wherein both length and height variations are made by stepless adjustments. when the lifting arm is in a fully raised position, a projecting upper end section of a major part of the lifting arm extends substantially horizontally; an effective length of the projecting upper end section is made variable by the provision of an extension element adjustably fixed to it; and characterised in that the lifting arm is variable in upstanding height by a provision of a lower end section slidably connected to the major part of the lifting arm, wherein both length and height variations are made by stepless adjustments.
An aircraft power generating assembly; the assembly comprising an electric machine, and a mechanical gear transmission connected to said electric machine; the assembly comprising: - a fixed supporting frame, - at least one rotary shaft (15;31) connected to the fixed supporting frame to rotate about a fixed hinge axis, and - first and second angular connecting means (4a, 8) for connecting said rotary shaft (15;31) to respective further rotary input/output shafts (3,6; 3,33); said electric machine comprising a rotor; characterized in that said electric machine is located between said first and second angular connecting means (4a, 8), and surrounds said rotary shaft (15;31) said rotor is connected angularly to said rotary shaft (15;31) by a releasable coupling device comprising an angular locking member, which is fitted in angularly fixed manner to said rotary shaft (15;31) and is axially movable between - a forward position, in which the rotor is locked in angularly fixed manner to the shaft (15;31), and - a withdrawn position, in which the rotor and the shaft (15;31) rotate freely with respect to each other. - a fixed supporting frame, - at least one rotary shaft (15;31) connected to the fixed supporting frame to rotate about a fixed hinge axis, and - first and second angular connecting means (4a, 8) for connecting said rotary shaft (15;31) to respective further rotary input/output shafts (3,6; 3,33); - a forward position, in which the rotor is locked in angularly fixed manner to the shaft (15;31), and - a withdrawn position, in which the rotor and the shaft (15;31) rotate freely with respect to each other.
Method for use in a telecommunications system, comprising: transmitting, via particular packets, at least one reference regarding decompression of a header; and comprising, at the Radio link control/Medium access control layer: transmitting other packets than the particular packets, in an unacknowledge mode without requesting feedback such as acknowledgments, if the other packets comprise changes compared to the reference, regarding the decompression; using an acknowledgment scheme for the particular packets; characterised by: receiving an acknowledgement message regardless of whether or not the acknowledgement scheme is being used; using the acknowledgement message for control purposes other than a valid acknowledgement for the other packets; and transmitting an indication that a valid acknowledgement of a particular packet is requested before or after transmission of said particular packet. transmitting, via particular packets, at least one reference regarding decompression of a header; and comprising, at the Radio link control/Medium access control layer: transmitting other packets than the particular packets, in an unacknowledge mode without requesting feedback such as acknowledgments, if the other packets comprise changes compared to the reference, regarding the decompression; using an acknowledgment scheme for the particular packets; transmitting other packets than the particular packets, in an unacknowledge mode without requesting feedback such as acknowledgments, if the other packets comprise changes compared to the reference, regarding the decompression; using an acknowledgment scheme for the particular packets; characterised by: receiving an acknowledgement message regardless of whether or not the acknowledgement scheme is being used; using the acknowledgement message for control purposes other than a valid acknowledgement for the other packets; and transmitting an indication that a valid acknowledgement of a particular packet is requested before or after transmission of said particular packet. receiving an acknowledgement message regardless of whether or not the acknowledgement scheme is being used; using the acknowledgement message for control purposes other than a valid acknowledgement for the other packets; and transmitting an indication that a valid acknowledgement of a particular packet is requested before or after transmission of said particular packet.
Apparatus for treating particulate material, comprising a process chamber (18, 108) which has a floor constructed from overlapping guide plates (22, 24) between which there are gaps (26, 26', 28, 28') present through which process air can be introduced approximately horizontally into the process chamber (18, 108), wherein the guide plates (22, 24) are arranged such that two flows of process air, which are oppositely directed one towards the other and meet along a riser zone, are formed, wherein in the riser zone a treatment medium can be sprayed onto the material via at least one linear spray nozzle, characterized in that the apparatus (10, 100) can be composed of individual performance modules (12, 102) of approximately same construction type and size, wherein the performance modules (12, 102) have a rectangular cross section and can be joined together via at least one open rectangle side to form a row, the longitudinal extents of the respective riser zones joining together in the direction of the row.
A method for updating a stored version of content stored in a storage device to an updated version using an update package, wherein the update package is adapted for updating an original version of content to the updated version and wherein the updating is carried out in accordance with an update sequence, the method comprising: determining whether the stored version is the original version and if so updating said stored version to said updated version using the update package; otherwise, while using an in-place status indication stored in one or more hosting blocks of the stored version, said in-place status indication being such that during its storing, content being part of said one or more hosting blocks is deleted in favour of said status indication while recovery data are stored in said update package for recovering said deleted content, determining whether the stored version is an intermediate version derived from the original version and if so, searching for a resume location in said stored version; updating said stored version to said updated version starting from the resume location using the update package and recovering the one or more hosting blocks to include content being part of the updated version by using said recovery data and, before successfully terminating the updating, deleting the in-place status indication. determining whether the stored version is the original version and if so updating said stored version to said updated version using the update package; otherwise, while using an in-place status indication stored in one or more hosting blocks of the stored version, said in-place status indication being such that during its storing, content being part of said one or more hosting blocks is deleted in favour of said status indication while recovery data are stored in said update package for recovering said deleted content, determining whether the stored version is an intermediate version derived from the original version and if so, searching for a resume location in said stored version; updating said stored version to said updated version starting from the resume location using the update package and recovering the one or more hosting blocks to include content being part of the updated version by using said recovery data and, before successfully terminating the updating, deleting the in-place status indication.
Nasal composition comprising: - a saline base comprising sodium chloride; - an active agent comprising copper, a mixture of copper and manganese, manganese, a combination of manganese and a calcium salt, or sulfur; - a mixture of a first hyaluronic acid with a second hyaluronic acid; wherein the first hyaluronic acid has a molecular weight of at most 50 000 daltons; and wherein the second hyaluronic acid has a molecular weight of at least 100 000 daltons and at most 500 000 daltons. - a saline base comprising sodium chloride; - an active agent comprising copper, a mixture of copper and manganese, manganese, a combination of manganese and a calcium salt, or sulfur; - a mixture of a first hyaluronic acid with a second hyaluronic acid; wherein the first hyaluronic acid has a molecular weight of at most 50 000 daltons; and wherein the second hyaluronic acid has a molecular weight of at least 100 000 daltons and at most 500 000 daltons.
One or more guide ribonucleic acids (gRNAs), the one or more gRNAs comprising a spacer sequence selected from the group consisting of the nucleic acid sequences in SEQ ID NOs: 55,709, 60,592, 55,559, 55,574, 55,575, 55,577, 55,578, 55,584, 55,586, 55,587, 55,600, 55,602, 55,605, 55,607, 55,616, 55,625, 55,627, 55,628, 55,633, 55,635, 55,639, 55,641, 55,642, 55,646, 55,669, 55,671, 55,672, 55,686, 55,688, 55,694, 55,696, 55,701, 55,704, 55,705, 55,708, 55,716, 55,718, 55,721, 55,722, 55,724, 55,726, 55,727, 55,730, 55,732, 55,743, 55,744, 55,748, 55,749, 55,751, 55,754, 55,762, 55,764, 55,771, 55,778, 55,781-55,783, 60,476, 60,477, 60,480-60,482, 60,485, 60,487, 60,490, 60,494, 60,496, 60,497, 60,504, 60,506, 60,515, 60,517, 60,519, 60,527, 60,529, 60,539-60,541, 60,555, 60,557, 60,558, 60,564, 60,569-60,572, 60,575, 60,578, 60,581, 60,588, 60,591, 60,599, 60,601, 60,605, 60,607, 60,618-60,620, 60,622, 60,630, 60,632, 60,633, 60,637, 60,639, 60,640, 60,642, 60,645, 60,648, 60,657, and 60,660.
A vehicular lighting device comprising a base, an outer lens attached to a front part of the base, a board having a light emitting diode mounted thereon and which is accommodated inside an inner space formed by the base and the outer lens, and an inner lens arranged between the outer lens and the board, wherein: the inner lens comprises a lens cut region that diffuses light from the board toward the outer lens as viewed from the front characterised in that the inner lens further comprises a protruding portion disposed at a position facing the light emitting diode and projecting toward the light emitting diode, and a roof extending from a base end side of the protruding portion along a transverse inward direction of the vehicle, wherein a partial space is formed in the inner space and surrounded by the board, the protruding portion, and the roof; and a harness, which is electrically connected to the light emitting diode, is connected to the board through the partial space. the inner lens comprises a lens cut region that diffuses light from the board toward the outer lens as viewed from the front characterised in that the inner lens further comprises a protruding portion disposed at a position facing the light emitting diode and projecting toward the light emitting diode, and a roof extending from a base end side of the protruding portion along a transverse inward direction of the vehicle, wherein a partial space is formed in the inner space and surrounded by the board, the protruding portion, and the roof; and a harness, which is electrically connected to the light emitting diode, is connected to the board through the partial space.
Hearing instrument system, comprising a housing, which has a plurality of connections (4, 7), and a tube, which has a plurality of lines, wherein the tube can be releasably connected to the housing by a connector, wherein the connector is designed to releasably connect the plurality of lines of the tube to the plurality of connections (4, 7) of the housing, and wherein the connections (4, 7) have different spatial orientations, characterized in that the connector is designed such that a first connection of the housing is connected by a sliding movement, and such that only thereafter is a second connection of the housing connected by a movement oriented transversely with respect to the sliding movement.
A method to validate ownership of a resource within a network, comprising: selecting a group of at least two validation agents (204a, 204b, 204d) such that network routes (212a, 212b, 212c) between a validation agent of the group and entities of a group of one or more entities to be queried about a property of the resource do not intersect; transmitting a property of the resource to be validated and an address indicator for the resource from a coordinating agent to the group of validation agents (204a, 204b, 204d); querying the property of the resource from the entities using the validation agents (204a, 204b, 204d) of the group to determine queried properties; and evaluating the queried properties to validate ownership of the resource. selecting a group of at least two validation agents (204a, 204b, 204d) such that network routes (212a, 212b, 212c) between a validation agent of the group and entities of a group of one or more entities to be queried about a property of the resource do not intersect; transmitting a property of the resource to be validated and an address indicator for the resource from a coordinating agent to the group of validation agents (204a, 204b, 204d); querying the property of the resource from the entities using the validation agents (204a, 204b, 204d) of the group to determine queried properties; and evaluating the queried properties to validate ownership of the resource.
A reinforced organic natural fiber composite material having a lambda value for thermal conductivity in the range 15-35 mW/m.K measured according to ISO 8301 is disclosed, said composite material comprising: - 25-85 % by weight hydrophobic nanoporous particles calculated on the total weight of the composite material, and - At least 10% by weight organic natural fibers having isocyanate reactive groups calculated on the total weight of the composite material, and - 1-15 % by weight binder, Wherein the binder used comprises emulsifiable polyisocyanate, water and surfactants. - 25-85 % by weight hydrophobic nanoporous particles calculated on the total weight of the composite material, and - At least 10% by weight organic natural fibers having isocyanate reactive groups calculated on the total weight of the composite material, and - 1-15 % by weight binder,
A method for monitoring a degree of clogging of the starting injectors of a turbine engine comprising: - a combustion chamber, into which at least one starting injector supplied with fuel opens, said starting injectors being suitable for initiating the combustion in said chamber by igniting the fuel, and - a turbine, rotated by the gases resulting from the combustion of the fuel in the chamber, the method being characterized in that it comprises the steps of: - measuring, during a phase of starting the turbine engine, the temperature of the exhaust gases at the outlet of the turbine, and - determining, from the changes over time in the temperature thus measured, a degree of clogging of the starting injectors. - a combustion chamber, into which at least one starting injector supplied with fuel opens, said starting injectors being suitable for initiating the combustion in said chamber by igniting the fuel, and - a turbine, rotated by the gases resulting from the combustion of the fuel in the chamber, - measuring, during a phase of starting the turbine engine, the temperature of the exhaust gases at the outlet of the turbine, and - determining, from the changes over time in the temperature thus measured, a degree of clogging of the starting injectors.
Method for remote control of an electric consumer device (3 0, 3 1, 3 2,..., 3 n) with a power adapter (2 0, 2 1, 2 2,..., 2 n) for switching on and off a power supply of the electric consumer end device (3 0, 3 1, 3 2,..., 3 n) connected with the power adapter (2 0, 2 1, 2 2,..., 2 n), wherein a central server controls the power adapter (2 0, 2 1, 2 2,..., 2 n) in dependence of stored instructions and switches on or off the power supply of the electric consumer device (3 0, 3 1, 3 2,..., 3 n), characterized in that the instructions are stored in a second server with a user database, wherein a user is registered with the second server, that the central server communicates with the second server and determines, when the next programmed recording is planned and when the associated electric consumer device (3 0, 3 1, 3 2,..., 3 n) shall be switched on, and that the electric consumer device (3 0, 3 1, 3 2,..., 3 n) connected with the power adapter (2 0, 2 1, 2 2,..., 2 n) is a Set-Top Box, a video recorder or a television.
A wound dressing material that supports cells in the wound area for the treatment of chronic wounds and that eliminates the risk of infection development in open wounds, characterized in that; it comprises graphene-based 2,3 dialdehyde bacterial cellulose compound.