A compound according to Formula or a pharmaceutically acceptable salt thereof, wherein n is 0 or 1; X is N or CH; Z is N, O or CH 2; Z 1 is CR 4 or N; R is hydrogen, C 1 -C 4 alkyl, monofluoromethyl, difluoromethyl or trifluoromethyl; R 1 is hydrogen, halogen, C 1 -C 4 alkyl or trifluoromethyl R 2 is piperidinyl which is N-substituted with C 1 -C 4 alkyl, C 3 -C 6 cycloalkyl, haloC 1 -C 4 alkyl, C C 1 -C 4 alkyl, S 2 C 1 -C 4 alkyl, C C 3 -C 6 cycloalkyl, C haloC 1 -C 4 alkyl, C C 1 -C 4 alkoxy, C C 1 -C 4 alkenoxy, heteroaryl or CO 2 benzyl, wherein each cycloalkyl is optionally substituted by hydroxy and each alkyl or alkoxy is optionally substituted by hydroxyl, C 1 -C 4 alkoxy or C 3 -C 6 cycloalkyl and wherein each heteroaryl has 5 or 6 ring atoms, 1, 2 or 3 ring heteroatoms independently selected from N, O and S and is optionally substituted with 1 or 2 C 1 -C 4 alkyl substituents, which piperidinyl ring is further optionally substituted by hydroxyl; R 3 is hydrogen, halogen or C 1 -C 4 alkyl; or R 2 and R 3, taken in combination, form a 5 or 6 member fused saturated azacyclic ring optionally substituted with benzyl or 5 or 6 member heteroarylmethyl, which heteroaryl has 1 or 2 ring heteroatoms independently selected from N, O and S; R 4 is hydrogen or C 1 -C 4 alkyl; R 5 and R 5a are independently selected from the group consisting of hydrogen and C 1 -C 4 alkyl; or R 5 and R 5a, taken in combination form a spirocyclic cyclopropyl ring; and when n is 0, R 6 and R 6a are each hydrogen and when n is 1, R 6 and R 6a are independently selected from the group consisting of hydrogen and C 1 -C 4 alkyl; or R 6 and R 6a, taken in combination form a spirocyclic cyclopropyl ring. n is 0 or 1; X is N or CH; Z is N, O or CH 2; Z 1 is CR 4 or N; R is hydrogen, C 1 -C 4 alkyl, monofluoromethyl, difluoromethyl or trifluoromethyl; R 1 is hydrogen, halogen, C 1 -C 4 alkyl or trifluoromethyl R 2 is piperidinyl which is N-substituted with C 1 -C 4 alkyl, C 3 -C 6 cycloalkyl, haloC 1 -C 4 alkyl, C C 1 -C 4 alkyl, S 2 C 1 -C 4 alkyl, C C 3 -C 6 cycloalkyl, C haloC 1 -C 4 alkyl, C C 1 -C 4 alkoxy, C C 1 -C 4 alkenoxy, heteroaryl or CO 2 benzyl, wherein each cycloalkyl is optionally substituted by hydroxy and each alkyl or alkoxy is optionally substituted by hydroxyl, C 1 -C 4 alkoxy or C 3 -C 6 cycloalkyl and wherein each heteroaryl has 5 or 6 ring atoms, 1, 2 or 3 ring heteroatoms independently selected from N, O and S and is optionally substituted with 1 or 2 C 1 -C 4 alkyl substituents, which piperidinyl ring is further optionally substituted by hydroxyl; R 3 is hydrogen, halogen or C 1 -C 4 alkyl; or R 2 and R 3, taken in combination, form a 5 or 6 member fused saturated azacyclic ring optionally substituted with benzyl or 5 or 6 member heteroarylmethyl, which heteroaryl has 1 or 2 ring heteroatoms independently selected from N, O and S; R 4 is hydrogen or C 1 -C 4 alkyl; R 5 and R 5a are independently selected from the group consisting of hydrogen and C 1 -C 4 alkyl; or R 5 and R 5a, taken in combination form a spirocyclic cyclopropyl ring; and when n is 0, R 6 and R 6a are each hydrogen and when n is 1, R 6 and R 6a are independently selected from the group consisting of hydrogen and C 1 -C 4 alkyl; or R 6 and R 6a, taken in combination form a spirocyclic cyclopropyl ring.