mhurhangee/ep-ind-claims huggingface dataset:
Method for reducing ultrasound data from one ultrasound signal comprising multiple ultrasound pulses, comprising the following steps in the method: a) rectification of the ultrasound signal, b) generation of an envelope curve around the maximum values of the rectified ultrasound signal, wherein the ultrasound pulses are represented in each case as curve sections with a single maximum value, c) generation of a first negative envelope curve signal reduced by a first factor f, and of an envelope curve signal for each ultrasound pulse, said signal not being modified but being delayed by a time period t d, d) addition of the first negatively reduced envelope curve signal and of the delayed envelope curve signal to form a first sum signal with a first zero crossing, wherein the first zero crossing represents a first time value, and e) allocation of an amplitude to the first time value, wherein the amplitude corresponds to a signal height consistent with a maximum peak height from the envelope curve within a time interval about the first time value. a) rectification of the ultrasound signal, b) generation of an envelope curve around the maximum values of the rectified ultrasound signal, wherein the ultrasound pulses are represented in each case as curve sections with a single maximum value, c) generation of a first negative envelope curve signal reduced by a first factor f, and of an envelope curve signal for each ultrasound pulse, said signal not being modified but being delayed by a time period t d, d) addition of the first negatively reduced envelope curve signal and of the delayed envelope curve signal to form a first sum signal with a first zero crossing, wherein the first zero crossing represents a first time value, and e) allocation of an amplitude to the first time value, wherein the amplitude corresponds to a signal height consistent with a maximum peak height from the envelope curve within a time interval about the first time value.
NDP-MSH or pharmaceutically acceptable salts thereof for use in treatment of inflammatory disorders of the CNS in a subject, wherein the inflammatory disorder of the CNS is multiple sclerosis.
A modular active grille shutter system (10; 100; 200) comprising: an active grille shutter system (10; 100; 200) having a frame located in a cooling pathway of a power source for a vehicle, wherein the frame includes a base integrated end cap and a base non-integrated end cap, wherein the base integrated end cap has an actuator pocket with a plurality of alternate actuator output axes (28a, 28b, 28c) located within the actuator pocket; a plurality of vanes (32a, 32b, 32c) rotatably connected at a first end to the base end cap and extending across the cooling pathway and connected at a second end to the base non-integrated end cap, wherein the plurality of vanes (32a, 32b, 32c) rotate between an open position and a closed position; and an actuator having a housing with a rotatable output positioned in an aperture formed in the housing, wherein the aperture and rotatable output are formed at a location that is alignable with one of the plurality of alternate output axes (28a, 28b, 28c), wherein the actuator is operably connected to the plurality of vanes (32a, 32b, 32c) such that rotation of the actuator output will rotate the plurality of vanes (32a, 32b, 32c). an active grille shutter system (10; 100; 200) having a frame located in a cooling pathway of a power source for a vehicle, wherein the frame includes a base integrated end cap and a base non-integrated end cap, wherein the base integrated end cap has an actuator pocket with a plurality of alternate actuator output axes (28a, 28b, 28c) located within the actuator pocket; a plurality of vanes (32a, 32b, 32c) rotatably connected at a first end to the base end cap and extending across the cooling pathway and connected at a second end to the base non-integrated end cap, wherein the plurality of vanes (32a, 32b, 32c) rotate between an open position and a closed position; and an actuator having a housing with a rotatable output positioned in an aperture formed in the housing, wherein the aperture and rotatable output are formed at a location that is alignable with one of the plurality of alternate output axes (28a, 28b, 28c), wherein the actuator is operably connected to the plurality of vanes (32a, 32b, 32c) such that rotation of the actuator output will rotate the plurality of vanes (32a, 32b, 32c).
An anti-podoplanin antibody for which an epitope is a polypeptide consisting of the amino acid sequence set forth in SEQ ID NO:1, and comprising: a) a heavy chain CDR1 consisting of the amino acid sequence set forth in SEQ ID NO:6; b) a heavy chain CDR2 consisting of the amino acid sequence set forth in SEQ ID NO:7; c) a heavy chain CDR3 consisting of the amino acid sequence set forth in SEQ ID NO:8; d) a light chain CDR1 consisting of the amino acid sequence set forth in SEQ ID NO:9; e) a light chain CDR2 consisting of the amino acid sequence set forth in SEQ ID NO:10; and f) a light chain CDR3 consisting of the amino acid sequence set forth in SEQ ID NO:11; and further comprising a human Fc region; wherein the antibody is a chimeric antibody with a human IgG1 subclass. a) a heavy chain CDR1 consisting of the amino acid sequence set forth in SEQ ID NO:6; b) a heavy chain CDR2 consisting of the amino acid sequence set forth in SEQ ID NO:7; c) a heavy chain CDR3 consisting of the amino acid sequence set forth in SEQ ID NO:8; d) a light chain CDR1 consisting of the amino acid sequence set forth in SEQ ID NO:9; e) a light chain CDR2 consisting of the amino acid sequence set forth in SEQ ID NO:10; and f) a light chain CDR3 consisting of the amino acid sequence set forth in SEQ ID NO:11;
A device for perforating a web made of a flexible material comprising at least a feed cylinder adapted to continuously deliver the web and at least one perforating cylinder, the surface of which is provided with perforating punches distributed in a predefined manner, with such perforating cylinder being associated with an anvil roll, intended to ensure the constant and regular pressing of the web in tangential contact with the perforating cylinder, with the device further comprising a perforation wastes suction collecting device, characterized in that the perforation wastes collecting device which combines air blowing with suction is positioned downstream of the perforating cylinder and of the anvil roll and so arranged with the latter as to facilitate the peeling off of the cut formed in the web from the associated perforation.
A method for determining a region in which a sensor must not be fitted of a windscreen of a utility vehicle, in order to prevent a vehicle driver's view from being obstructed by the sensor, this sensor being in particular a photo or video camera, characterised by the following steps: I the measurement of the distance (H S) between a seat surface of a vehicle driver's seat and the surface of the ground on which the wheels of the utility vehicle stand; II the measurement of a distance (W S) between a seatback of a vehicle driver's seat and the inner face of the windscreen at a predetermined height (H P) above the seat surface of the vehicle driver's seat parallel to the surface of the ground; III the determination of coordinates (H L, V L) of a vertex of a rectangular region in which a sensor must not be fitted on the windscreen on the basis of the distance values measured in steps I and II using a computing algorithm, H L being the distance from the vertex to a notional centre line (Ms) of the vehicle driver's seat in the direction of a passenger-side edge of the windscreen, and V L being the distance between the vertex and the surface of the ground, the region in which a sensor must not be fitted of the windscreen extending from the vertex vertically to the upper edge and horizontally to the driver-side edge of the windscreen. I the measurement of the distance (H S) between a seat surface of a vehicle driver's seat and the surface of the ground on which the wheels of the utility vehicle stand; II the measurement of a distance (W S) between a seatback of a vehicle driver's seat and the inner face of the windscreen at a predetermined height (H P) above the seat surface of the vehicle driver's seat parallel to the surface of the ground; III the determination of coordinates (H L, V L) of a vertex of a rectangular region in which a sensor must not be fitted on the windscreen on the basis of the distance values measured in steps I and II using a computing algorithm, H L being the distance from the vertex to a notional centre line (Ms) of the vehicle driver's seat in the direction of a passenger-side edge of the windscreen, and V L being the distance between the vertex and the surface of the ground, the region in which a sensor must not be fitted of the windscreen extending from the vertex vertically to the upper edge and horizontally to the driver-side edge of the windscreen. H L being the distance from the vertex to a notional centre line (Ms) of the vehicle driver's seat in the direction of a passenger-side edge of the windscreen, and V L being the distance between the vertex and the surface of the ground,
A mutant 3-hydroxybutyrate dehydrogenase (3-HBDH) from Alcaligenes faecalis with improved performance relative to the wild-type 3-HBDH, wherein the mutant comprises an amino acid sequence that is at least 80 % identical to the amino acid sequence of SEQ ID NO: 1 (3-HBDH from Alcaligenes faecalis; wild-type 3-HBDH) or the amino acid sequence of SEQ ID NO: 2 (extended core sequence of wild-type 3-HBDH) and wherein the mutant has at least three amino acid substitutions relative to the wild-type 3-HBDH, wherein the amino acid at the position corresponding to - position 253 of SEQ ID NO: 1 is substituted with Ile, Ala or Cys, - position 233 of SEQ ID NO: 1 is substituted with Ser, Ile, Ala, Pro, Arg, Thr, Lys, or Cys, and - position 234 of SEQ ID NO: 1 is substituted with Thr. - position 253 of SEQ ID NO: 1 is substituted with Ile, Ala or Cys, - position 233 of SEQ ID NO: 1 is substituted with Ser, Ile, Ala, Pro, Arg, Thr, Lys, or Cys, and - position 234 of SEQ ID NO: 1 is substituted with Thr.
A laminate for a blister package, comprising a substrate film, an adhesive resin layer, and an absorbing film in that order; wherein, the adhesive resin layer has a thickness of 25 μm to 100 μm, and the absorbing film comprises an absorbing layer containing a thermoplastic resin and an inorganic absorbent. the adhesive resin layer has a thickness of 25 μm to 100 μm, and the absorbing film comprises an absorbing layer containing a thermoplastic resin and an inorganic absorbent.
A method for managing utilization of un-licensed frequency spectrum resources for secondary systems (a, b, c), comprising: assigning a first un-licensed frequency spectrum resource in an availability time period to a first secondary system (a, b, c); characterised by: reassigning at least part of the first un-licensed frequency spectrum resource during the availability time period based on the current resource utilization by the first and the second secondary systems (a, b, c); and controlling interference to other secondary systems (a, b, c) when reassigning the at least part of first un-licensed frequency spectrum resource to the second secondary system (a, b, c), wherein the steps of assigning and reassigning the first un-licensed frequency spectrum resource are under protection of a primary system (A, B, C) which has a licensed frequency spectrum usage right. reassigning at least part of the first un-licensed frequency spectrum resource during the availability time period based on the current resource utilization by the first and the second secondary systems (a, b, c); and controlling interference to other secondary systems (a, b, c) when reassigning the at least part of first un-licensed frequency spectrum resource to the second secondary system (a, b, c), wherein the steps of assigning and reassigning the first un-licensed frequency spectrum resource are under protection of a primary system (A, B, C) which has a licensed frequency spectrum usage right.
A process for preparing a bituminous binder, which is intended to be used for forming a bituminous coating, comprising the placing in contact, with stirring for at least 10 minutes, of bitumen(s) with at least one olefinic polymer bearing at least one epoxy functional group, said polymer representing between 0.01% and 20% by weight of the bitumen-polymer blend, characterized in that a basic adjuvant is added to the bitumen-polymer blend, this adjuvant consisting of a basic compound chosen from an imidazole or a tertiary amine bearing three alkyl radicals, which is capable of promoting chemical bonding between the bitumen and the olefinic polymer bearing at least one epoxy functional group, said adjuvant representing between 0.01% and 5% by weight of the bitumen-polymer blend.
Method of cooking for a food-cooking apparatus comprising a receiving means provided to receive the food, a steering means disposed within the receiving means, at least one main heating means, the receiving means and the stirring means being designed to be made to rotate one relative to the other, the receiving means having a upper opening, the appliance comprising means for controlling at least the relative rotation and the at least one main heating means, characterised in that the cooking method comprises: - a first cooking step during which the relative rotation of the receiving means and the stirring means is neutralized and the at least one main heating means is controlled to regulate the temperature to a first set-point value; - a second cooking step during which the relative rotation of the receiving means and the stirring means is active and the at least one main heating means is controlled to regulate the temperature to a second set-point value that is greater than the first set-point value, before the cooking steps, the food covered with breadcrumbs are placed in the receiving means, the duration of the first cooking step is between 35%-45% of the cumulative time of the two cooking steps during the first step, the non-rotation of the stirring means makes it possible to preserve the breadcrumbs covering the food, and at the end of this first step the breadcrumbs have gained in mechanical strength and can withstand the stirring carried out during the second step; the main heating means generates a heating stream entering the receiving means through the upper opening. - a first cooking step during which the relative rotation of the receiving means and the stirring means is neutralized and the at least one main heating means is controlled to regulate the temperature to a first set-point value; - a second cooking step during which the relative rotation of the receiving means and the stirring means is active and the at least one main heating means is controlled to regulate the temperature to a second set-point value that is greater than the first set-point value, before the cooking steps, the food covered with breadcrumbs are placed in the receiving means, the duration of the first cooking step is between 35%-45% of the cumulative time of the two cooking steps during the first step, the non-rotation of the stirring means makes it possible to preserve the breadcrumbs covering the food, and at the end of this first step the breadcrumbs have gained in mechanical strength and can withstand the stirring carried out during the second step; the main heating means generates a heating stream entering the receiving means through the upper opening.
A diagnosis system of a hydraulic machine, the hydraulic machine comprising: a rotation shaft; a cylinder; a piston forming a working chamber together with the cylinder; and a high-pressure valve and a low-pressure valve provided for the working chamber, wherein the hydraulic machine is configured to perform conversion between rotational motion of the rotation shaft and reciprocating motion of the piston; and characterised in that the diagnosis system comprises: a pressure sensor for measuring a pressure in the working chamber; and a first abnormality determination part for determining an abnormality of the hydraulic machine on the basis of a measurement result obtained by the pressure sensor, wherein at least one of the high-pressure valve and the low-pressure valve is a valve that is configured such that a valve body (35,48) is movable, by supply control of an excitation current, between a normal position at which the valve is not supplied with the excitation current and an excitation position at which the valve is supplied with the excitation current, and wherein the first abnormality determination part is configured to determine the abnormality of the hydraulic machine on the basis of the measurement result obtained by the pressure sensor when the valve is not supplied with the excitation current. a rotation shaft; a cylinder; a piston forming a working chamber together with the cylinder; and a high-pressure valve and a low-pressure valve provided for the working chamber, wherein the hydraulic machine is configured to perform conversion between rotational motion of the rotation shaft and reciprocating motion of the piston; and characterised in that the diagnosis system comprises: a pressure sensor for measuring a pressure in the working chamber; and a first abnormality determination part for determining an abnormality of the hydraulic machine on the basis of a measurement result obtained by the pressure sensor, a pressure sensor for measuring a pressure in the working chamber; and a first abnormality determination part for determining an abnormality of the hydraulic machine on the basis of a measurement result obtained by the pressure sensor, wherein at least one of the high-pressure valve and the low-pressure valve is a valve that is configured such that a valve body (35,48) is movable, by supply control of an excitation current, between a normal position at which the valve is not supplied with the excitation current and an excitation position at which the valve is supplied with the excitation current, and wherein the first abnormality determination part is configured to determine the abnormality of the hydraulic machine on the basis of the measurement result obtained by the pressure sensor when the valve is not supplied with the excitation current.
Electrical heating appliance comprising an emissive surface and a phase-change liquid, comprising: - an electrical heating element that supplies vapour to a closed casing that forms the heating surface, the phase-change liquid transferring heat by means of evaporation/condensation, said closed casing forming a pressure-resistant hermetic chamber, - a tank having a small volume that is provided with a heating member and contains the liquid, said electrical heating appliance being characterised in that it comprises - said closed casing in the form of a panel that is mounted on the tank, which tank is in communication with the panel in order to allow the vapour to pass through, - at least one condensate channel - that opens in the upper portion of the casing, - that is separated from the direct flow of the vapour emitted by the tank, - that constitutes a cold region that forms a condensate trap, and - that conveys the condensates in a tank. - an electrical heating element that supplies vapour to a closed casing that forms the heating surface, the phase-change liquid transferring heat by means of evaporation/condensation, said closed casing forming a pressure-resistant hermetic chamber, - a tank having a small volume that is provided with a heating member and contains the liquid, said electrical heating appliance being characterised in that it comprises - said closed casing in the form of a panel that is mounted on the tank, which tank is in communication with the panel in order to allow the vapour to pass through, - at least one condensate channel - that opens in the upper portion of the casing, - that is separated from the direct flow of the vapour emitted by the tank, - that constitutes a cold region that forms a condensate trap, and - that conveys the condensates in a tank. - that opens in the upper portion of the casing, - that is separated from the direct flow of the vapour emitted by the tank, - that constitutes a cold region that forms a condensate trap, and - that conveys the condensates in a tank.
A computer-implemented method comprising: computing a first rate of change in blood glucose concentration as observed from blood glucose reference samples obtained from a body; computing a second rate of change in said blood glucose concentration as observed at a blood glucose sensor; expressing a relative comparison of said first rate of change and said second rate of change as an angle in a polar plot; and generating signals to present said polar plot in a visual medium. computing a first rate of change in blood glucose concentration as observed from blood glucose reference samples obtained from a body; computing a second rate of change in said blood glucose concentration as observed at a blood glucose sensor; expressing a relative comparison of said first rate of change and said second rate of change as an angle in a polar plot; and generating signals to present said polar plot in a visual medium.
A refrigerated merchandiser comprising: a case defining a product display area and including a base, a lower flue, a first air passageway, and a second air passageway, the first air passageway and second air passageway in fluid communication with the lower flue and with the product display area; an evaporator positioned in the first air passageway; a fan assembly positioned in the base in fluid communication with the lower flue to generate an airflow; and a fan plenum into which the fan assembly Is disposed, the fan plenum including an airflow divider to direct a first portion of the airflow to the first air passageway and to direct a second portion of the airflow to the second air passageway, wherein the proportion of air between the first portion and the second portion is a function of the position and geometry of the airflow divider. a case defining a product display area and including a base, a lower flue, a first air passageway, and a second air passageway, the first air passageway and second air passageway in fluid communication with the lower flue and with the product display area; an evaporator positioned in the first air passageway; a fan assembly positioned in the base in fluid communication with the lower flue to generate an airflow; and a fan plenum into which the fan assembly Is disposed, the fan plenum including an airflow divider to direct a first portion of the airflow to the first air passageway and to direct a second portion of the airflow to the second air passageway, wherein the proportion of air between the first portion and the second portion is a function of the position and geometry of the airflow divider.
2,2'-Dithio-bis-ethane sulfonate or a pharmaceutically acceptable salt thereof, for use in increasing survival time in a patient with non-small cell lung carcinoma, wherein said use comprises determining whether said carcinoma either: (i) overexpresses thioredoxin or glutaredoxin and/or (ii) exhibits evidence of thioredoxin-mediated or glutaredoxin-mediated resistance to platinum and taxane chemotherapeutic agents used to treat said patient; and, in the case of a positive determination, administering to the patient said 2,2'-dithio-bis-ethane sulfonate or pharmaceutically-acceptable salt thereof in a medically-sufficient dose, either prior to, concomitantly with, or subsequent to the administration of said platinum and taxane chemotherapeutic agents whose cytotoxic or cytostatic activity is adversely affected by either: (i) the overexpression of thioredoxin or glutaredoxin and/or (ii) thioredoxin-mediated or glutaredoxin-mediated treatment resistance.