A high-strength steel sheet having excellent brittle crack arrestability, the high-strength steel of the sheet consisting of: 0.05 wt% to 0.1 wt% of carbon, 0.9 wt% to 1.5 wt% of manganese (Mn), 0.8 wt% to 1.5 wt% of nickel (Ni), 0.005 wt% to 0.1 wt% of niobium (Nb), 0.005 wt% to 0.1 wt% of titanium (Ti), 0.1 wt% to 0.6 wt% of copper (Cu), 0.1 wt% to 0.4 wt% of silicon (Si), 100 ppm or less of phosphorous, 40 ppm or less of sulfur, and the remainder being iron (Fe) and other inevitably contained impurities, the high-strength steel having a microstructure being one structure selected from the group consisting of a single-phase structure of ferrite, a single-phase structure of bainite, a complex-phase structure of ferrite and bainite, a complex-phase structure of ferrite and pearlite, and a complex-phase structure of ferrite, bainite, and pearlite, and having a thickness of 50 mm or more, wherein the contents of Cu and Ni are set such that a Cu/Ni weight ratio is 0.6 or less, wherein the ferrite is acicular ferrite or polygonal ferrite, and the bainite is granular bainite, wherein in the high-strength steel sheet, a grain size having a high-angle boundary of 15 degrees or more measured, in an electron backscattered diffraction (EBSD) method, in a central portion of a steel thickness, is 30μm or less, wherein an area ratio of a plane forming an angle within 15 degrees with respect to a plane perpendicular to a rolling direction in a region of the high-strength steel sheet in a range of 20% of an overall steel thickness based on a position equal to 1/2 of the steel thickness is 40% or less, and wherein the yield strength of the high-strength steel is 390 MPa or more. 0.05 wt% to 0.1 wt% of carbon, 0.9 wt% to 1.5 wt% of manganese (Mn), 0.8 wt% to 1.5 wt% of nickel (Ni), 0.005 wt% to 0.1 wt% of niobium (Nb), 0.005 wt% to 0.1 wt% of titanium (Ti), 0.1 wt% to 0.6 wt% of copper (Cu), 0.1 wt% to 0.4 wt% of silicon (Si), 100 ppm or less of phosphorous, 40 ppm or less of sulfur, and the remainder being iron (Fe) and other inevitably contained impurities, the high-strength steel having a microstructure being one structure selected from the group consisting of a single-phase structure of ferrite, a single-phase structure of bainite, a complex-phase structure of ferrite and bainite, a complex-phase structure of ferrite and pearlite, and a complex-phase structure of ferrite, bainite, and pearlite, and having a thickness of 50 mm or more, wherein the contents of Cu and Ni are set such that a Cu/Ni weight ratio is 0.6 or less, wherein the ferrite is acicular ferrite or polygonal ferrite, and the bainite is granular bainite, wherein in the high-strength steel sheet, a grain size having a high-angle boundary of 15 degrees or more measured, in an electron backscattered diffraction (EBSD) method, in a central portion of a steel thickness, is 30μm or less, wherein an area ratio of a plane forming an angle within 15 degrees with respect to a plane perpendicular to a rolling direction in a region of the high-strength steel sheet in a range of 20% of an overall steel thickness based on a position equal to 1/2 of the steel thickness is 40% or less, and wherein the yield strength of the high-strength steel is 390 MPa or more.