mhurhangee/ep-ind-claims huggingface dataset:
A kit comprising (i) an aqueous liposome dispersion comprising - liposomes comprising 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine (DOPE) and at least one cationic lipid selected from the group consisting of 1,2-di-O-octadecenyl-3-trimethylammoniumpropane (DOTMA) and 1,2-dioleoyl-3-trimethylammoniumpropane (DOTAP), said liposomes being cationic at physiological pH, wherein the physiological pH has a pH of between 6 and 8, and - at least one pH adjusting agent, wherein the aqueous liposome dispersion has a pH of between 2 and 4.5, and (ii) in a separate container, a pharmaceutically active nucleic acid, wherein the pharmaceutically active nucleic acid is provided in a buffered solution having a pH of between 6 and 8. (i) an aqueous liposome dispersion comprising - liposomes comprising 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine (DOPE) and at least one cationic lipid selected from the group consisting of 1,2-di-O-octadecenyl-3-trimethylammoniumpropane (DOTMA) and 1,2-dioleoyl-3-trimethylammoniumpropane (DOTAP), said liposomes being cationic at physiological pH, wherein the physiological pH has a pH of between 6 and 8, and - at least one pH adjusting agent, wherein the aqueous liposome dispersion has a pH of between 2 and 4.5, and - liposomes comprising 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine (DOPE) and at least one cationic lipid selected from the group consisting of 1,2-di-O-octadecenyl-3-trimethylammoniumpropane (DOTMA) and 1,2-dioleoyl-3-trimethylammoniumpropane (DOTAP), said liposomes being cationic at physiological pH, wherein the physiological pH has a pH of between 6 and 8, and - at least one pH adjusting agent, (ii) in a separate container, a pharmaceutically active nucleic acid, wherein the pharmaceutically active nucleic acid is provided in a buffered solution having a pH of between 6 and 8.
Device configured for providing a spreading function to a surgical instrument wherein the surgical instrument comprises a linear body of circular cross-section with 5 mm in diameter, wherein the device comprises a body comprising: - a first side, and - a second side comprising: - at least two grooves configured to perform a folding of the body; and - a housing configured to be transversed by the linear body of circular section of the surgical instrument; and wherein the body is configured to adopt two positions: a U-shaped folded position and a flat unfolded position; characterised in that the second side further comprises two tabs having a section with a circular sector shape and spaced a distance apart such that the linear body of circular section can be housed between the tabs; and in that in the flat unfolded position, the housing and the two tabs are configured to simultaneously receive the linear body, and wherein the surgical instrument is a laparoscopic instrument. - a first side, and - a second side comprising: - at least two grooves configured to perform a folding of the body; and - a housing configured to be transversed by the linear body of circular section of the surgical instrument; - at least two grooves configured to perform a folding of the body; and - a housing configured to be transversed by the linear body of circular section of the surgical instrument; and wherein the body is configured to adopt two positions: a U-shaped folded position and a flat unfolded position; characterised in that the second side further comprises two tabs having a section with a circular sector shape and spaced a distance apart such that the linear body of circular section can be housed between the tabs; and in that in the flat unfolded position, the housing and the two tabs are configured to simultaneously receive the linear body, and wherein the surgical instrument is a laparoscopic instrument.
Commercial vehicle tyre of radial construction having a tread, a belt bandage comprising a plurality of belt plies, an airtight inner layer running along the inside of the tyre, an at least single-ply carcass insert comprising steel cords as strength members and a squeegee ply arranged between the carcass insert and the inner layer which is based on a rubber mixture containing the fillers carbon black and silica in a proportion of 20 phr to < 43 phr and a sulfur accelerator crosslinking system comprising at least one accelerator from the group of benzothiazolesulfenamide accelerators in a proportion of 1 phr to 3 phr, characterized in that the proportion of sulfur in the sulfur accelerator crosslinking system of the rubber mixture is 4 phr to 7 phr.
A male RJ45 connector for an RJ45 electrical connection cord provided with a cable having four pairs of conducting wires that are configured to be electrically connected to said male connector (5, 6), which connector comprises a printed circuit having a first face and a second face which is an opposite face to said first face, as well as a plurality of electrical conveyance tracks to which said pairs of conducting wires are configured to be connected electrically, a spreader system mounted on said printed circuit and configured to separate, electrically insulate and electrically shield said pairs of conducting wires from each other; said male connector (5, 6) being characterized in that: - said printed circuit comprises at least one earthing plate sandwiched between its first and second faces (23, 24) and a central throughslot extending longitudinally in said printed circuit and opening on a side of said printed circuit, said central through-slot being configured to pass through both said first and second faces (23, 24) and said at least one electrical earthing plate; - said spreader system comprises a separator body and an extension body projecting from said separator body, said extension body being provided with a hollow configured to receive said printed circuit and an electrically and/or magnetically shielding central wall dividing said hollow into two parts and being configured to be inserted at least mostly into said central through-slot of said printed circuit; and said electrically and/or magnetically shielding central wall and said at least one earthing plate of said printed circuit are configured to be electrically interconnected and thus form an electrically and/or magnetically shielding barrier between each pair of conducting wires. - said printed circuit comprises at least one earthing plate sandwiched between its first and second faces (23, 24) and a central throughslot extending longitudinally in said printed circuit and opening on a side of said printed circuit, said central through-slot being configured to pass through both said first and second faces (23, 24) and said at least one electrical earthing plate; - said spreader system comprises a separator body and an extension body projecting from said separator body, said extension body being provided with a hollow configured to receive said printed circuit and an electrically and/or magnetically shielding central wall dividing said hollow into two parts and being configured to be inserted at least mostly into said central through-slot of said printed circuit;
A transfer device comprising: a housing having a top, a side wall, an open bottom, said open bottom permitting insertion of a vial within said housing; a piercing member mounted within said housing, said piercing member having a piercing tip located at a bottom end thereof, said piercing member having an interior passageway formed therein; a connector located on an exterior side of said top; a moveable member mounted within said housing, said moveable member being moveable from a first position wherein said moveable member prevents access to said piercing tip and a second position permitting access to said piercing tip when said vial is inserted in said housing, characterized in that said moveable member and said housing causing said moveable member to rotate when said moveable member moves upwardly upon insertion of said vial, said moveable member returning to a third locked position upon removal of said vial, said third locked position being such that a further vial cannot be inserted into said housing. a housing having a top, a side wall, an open bottom, said open bottom permitting insertion of a vial within said housing; a piercing member mounted within said housing, said piercing member having a piercing tip located at a bottom end thereof, said piercing member having an interior passageway formed therein; a connector located on an exterior side of said top; a moveable member mounted within said housing, said moveable member being moveable from a first position wherein said moveable member prevents access to said piercing tip and a second position permitting access to said piercing tip when said vial is inserted in said housing, characterized in that said moveable member and said housing causing said moveable member to rotate when said moveable member moves upwardly upon insertion of said vial, said moveable member returning to a third locked position upon removal of said vial, said third locked position being such that a further vial cannot be inserted into said housing.
A capacitor comprising: a dielectric film; a first conductor layer and a second conductor layer which are disposed on opposite surfaces of the dielectric film, the dielectric film including the first and second conductor layers (3, 4) being wound into a rod shape; a first electrode led out from the first conductor layer; and a second electrode led out from the second conductor layer, wherein at least one of the first conductor layer and the second conductor layer includes a first area-changeable conductor pattern (33a - 33g), which is disposed on an outer circumference side of the capacitor wound into the rod shape characterized in that the first area-changeable conductor pattern (33a - 33g) is configured to receive physical treatment from outside to change the size of a conductor area of the at least one of the first conductor layer and the second conductor layer for the capacitor, such that a capacitance value of the capacitor is selectively set corresponding to the change in the conductor area as effected by the physical treatment. a dielectric film; a first conductor layer and a second conductor layer which are disposed on opposite surfaces of the dielectric film, the dielectric film including the first and second conductor layers (3, 4) being wound into a rod shape; a first electrode led out from the first conductor layer; and a second electrode led out from the second conductor layer, wherein at least one of the first conductor layer and the second conductor layer includes a first area-changeable conductor pattern (33a - 33g), which is disposed on an outer circumference side of the capacitor wound into the rod shape characterized in that the first area-changeable conductor pattern (33a - 33g) is configured to receive physical treatment from outside to change the size of a conductor area of the at least one of the first conductor layer and the second conductor layer for the capacitor, such that a capacitance value of the capacitor is selectively set corresponding to the change in the conductor area as effected by the physical treatment.
An aircraft wing, comprising: an elongate wing spar that may flex during flight; a plurality of wing segments supported on the spar, each of the plurality of wing segments including a pair of spaced apart ribs; and joints between each of the wing segments and the spar for allowing movement of the wing segments relative to the spar, Characterized in that the joints include pivotal connections between the ribs and the wing spar. an elongate wing spar that may flex during flight; a plurality of wing segments supported on the spar, each of the plurality of wing segments including a pair of spaced apart ribs; and joints between each of the wing segments and the spar for allowing movement of the wing segments relative to the spar, Characterized in that the joints include pivotal connections between the ribs and the wing spar.
A control method for a printer equipped with a buzzer, comprising steps of: receiving a printing control command for controlling printing by the printer; storing buzzer settings including one or more trigger events and one or more buzzing parameters, wherein a buzzer trigger event is an event that is to trigger sounding of a buzzer, and the buzzing parameters determine the way in which the buzzer is to sound; detecting whether any of the trigger events occurs; and causing the buzzer to sound in response to each detected trigger event in accordance with the one or more stored buzzing parameters; characterized by receiving a buzzer configuration command specifying one or more predetermined buzzer trigger events and one or more buzzing parameters, wherein the receiving of a printing control command and the receiving of a buzzer configuration command comprises receiving a print command stream representing a command set including the buzzer configuration command and the printing control command; wherein it is determined if the buzzer configuration command is contained in the command set received before the printing control command, the buzzer settings being stored if the buzzer configuration command is included, wherein the print command stream includes as part of the printing control command a new-page command specifying a new page process, and/or a stop printing command specifying a process that is executed after the printing process ends; and wherein the new page command and/or stop printing command is set as a buzzer trigger event by the buzzer configuration command. receiving a printing control command for controlling printing by the printer; storing buzzer settings including one or more trigger events and one or more buzzing parameters, wherein a buzzer trigger event is an event that is to trigger sounding of a buzzer, and the buzzing parameters determine the way in which the buzzer is to sound; detecting whether any of the trigger events occurs; and causing the buzzer to sound in response to each detected trigger event in accordance with the one or more stored buzzing parameters; characterized by receiving a buzzer configuration command specifying one or more predetermined buzzer trigger events and one or more buzzing parameters, wherein the receiving of a printing control command and the receiving of a buzzer configuration command comprises receiving a print command stream representing a command set including the buzzer configuration command and the printing control command; wherein it is determined if the buzzer configuration command is contained in the command set received before the printing control command, the buzzer settings being stored if the buzzer configuration command is included, wherein the print command stream includes as part of the printing control command a new-page command specifying a new page process, and/or a stop printing command specifying a process that is executed after the printing process ends; and wherein the new page command and/or stop printing command is set as a buzzer trigger event by the buzzer configuration command.
A mobile terminal, comprising: a touch panel configured to detect a touch position; a vibration generation means configured to generate vibration; an assignment means configured to assign different vibration area patterns, that define vibration areas on the touch panel which generate the vibration, to a plurality of internal states which identifies the originator of an incoming communication, respectively; and a control means configured to activate, according to a current internal state, the vibration area pattern assigned to the internal state and to control the vibration generation means so as to generate the vibration while the vibration area is being touched by the user. a touch panel configured to detect a touch position; a vibration generation means configured to generate vibration; an assignment means configured to assign different vibration area patterns, that define vibration areas on the touch panel which generate the vibration, to a plurality of internal states which identifies the originator of an incoming communication, respectively; and a control means configured to activate, according to a current internal state, the vibration area pattern assigned to the internal state and to control the vibration generation means so as to generate the vibration while the vibration area is being touched by the user.
A method for adjusting a physical layer interface, hereinafter referred as to PHY, in a flexible Ethernet FlexE group, comprising: determining, by a receiving device, that a first physical port PHY needs to be added to a first FlexE group in a working state; and aligning all PHY through performing, by the receiving device for each PHY in the first FlexE group, deskew on the first PHY or the respective PHY in the first FlexE group based on a received data stream corresponding to the first PHY and a received data stream corresponding to the respective PHY in the first FlexE group, and restoring a data stream corresponding to a client Client from a PHY in the first FlexE group; wherein performing deskew comprises waiting, by the one of the first PHY or the respective PHY in the first FlexE group receiving a feature block earlier than the other, for the other to receive the same feature block, by buffering a quantity of blocks; characterized in that if skew between the data stream corresponding to the first PHY and the data stream corresponding to each PHY in the first FlexE group after the deskew is performed is zero, the methods further comprises restoring, by the receiving device, a data stream corresponding to a client from a PHY in a second FlexE group, wherein the second FlexE group is a FlexE group after the first PHY is added to the first FlexE group. determining, by a receiving device, that a first physical port PHY needs to be added to a first FlexE group in a working state; and aligning all PHY through performing, by the receiving device for each PHY in the first FlexE group, deskew on the first PHY or the respective PHY in the first FlexE group based on a received data stream corresponding to the first PHY and a received data stream corresponding to the respective PHY in the first FlexE group, and restoring a data stream corresponding to a client Client from a PHY in the first FlexE group; wherein performing deskew comprises waiting, by the one of the first PHY or the respective PHY in the first FlexE group receiving a feature block earlier than the other, for the other to receive the same feature block, by buffering a quantity of blocks; characterized in that if skew between the data stream corresponding to the first PHY and the data stream corresponding to each PHY in the first FlexE group after the deskew is performed is zero, the methods further comprises restoring, by the receiving device, a data stream corresponding to a client from a PHY in a second FlexE group, wherein the second FlexE group is a FlexE group after the first PHY is added to the first FlexE group.
A nasal fluid dispenser device comprising a body comprising a hollow sleeve and a top surface, and an actuator member that is mounted to slide in said body so as to actuate the device, the device being characterized in that it further comprises two nasal extensions (20, 30), at least one of which forms a dispenser head provided with a respective dispenser orifice (21, 31), said nasal extensions extending from said top surface, each dispenser head being connected, during actuation, to a respective reservoir that is arranged in said body, said two nasal extensions (20, 30) forming an angle lying in the range 30° to 60° relative to a longitudinal central axis of said body.
Drive device for providing a driving movement of a drive body, comprising the drive body, which comprises a magnet arrangement, wherein the drive device comprises at least two magnetic field sensor elements (7, 8, 9, 11, 12, 13) which are spaced apart from one another and are adapted to provide magnetic field measured values, and wherein the drive device comprises a detection apparatus which is adapted to detect a position of the drive body on the basis of one or more of the magnetic field measured values, wherein the detection apparatus is adapted to check, in accordance with at least two magnetic field measured values from at least two magnetic field sensor elements (7, 8, 9, 11, 12, 13) adapted as pixel cells which are arranged on the same chip and belong to the same sensor cell (14, 15, 16), or in accordance with at least two position values, which are based on at least two magnetic field measured values detected by at least two magnetic field sensor elements (7, 8, 9, 11, 12, 13) adapted as pixel cells which are arranged on the same chip and belong to the same sensor cell (14, 15, 16), and taking into account checking information which represents a target relationship between magnetic field measured values or position values, respectively, the validity of the position detection and to provide a validity signal as a function of the result of the check.
An organic compound having the following structure of Chemical Formula 1: wherein R 1 is a C 6 -C 30 aryl amino group or a C 3 -C 30 hetero-aryl amino group, wherein each of an aromatic ring and a heteroaromatic ring in the C 6 -C 30 aryl amino group and/or the C 3 -C 30 hetero-aryl amino group is unsubstituted or substituted with at least one group selected from cyano, C 1 -C 10 alkyl, C 1 -C 10 alkoxy, C 6 -C 30 aryl and C 3 -C 30 hetero aryl; R 2 is hydrogen, an unsubstituted or substituted C 1 -C 20 alkyl group, an unsubstituted or substituted C 1 -C 20 alkoxy group, an unsubstituted or substituted aromatic group or an unsubstituted or substituted heteroaromatic group; each of R 3 and R 4 is independently an unsubstituted or substituted aromatic group or an unsubstituted or substituted heteroaromatic group; and each of R 5 and R 6 is independently hydrogen, an unsubstituted or substituted C 1 -C 10 alkyl group, an unsubstituted or substituted C 1 -C 10 alkoxy group, an unsubstituted or substituted aromatic group or an unsubstituted or substituted heteroaromatic group, wherein the aromatic group is a group which has one or more C 6 -C 30 aryl groups, wherein the heteroaromatic group is a group which has one or more C 3 -C 30 heteroaryl groups. wherein R 1 is a C 6 -C 30 aryl amino group or a C 3 -C 30 hetero-aryl amino group, wherein each of an aromatic ring and a heteroaromatic ring in the C 6 -C 30 aryl amino group and/or the C 3 -C 30 hetero-aryl amino group is unsubstituted or substituted with at least one group selected from cyano, C 1 -C 10 alkyl, C 1 -C 10 alkoxy, C 6 -C 30 aryl and C 3 -C 30 hetero aryl; R 2 is hydrogen, an unsubstituted or substituted C 1 -C 20 alkyl group, an unsubstituted or substituted C 1 -C 20 alkoxy group, an unsubstituted or substituted aromatic group or an unsubstituted or substituted heteroaromatic group; each of R 3 and R 4 is independently an unsubstituted or substituted aromatic group or an unsubstituted or substituted heteroaromatic group; and each of R 5 and R 6 is independently hydrogen, an unsubstituted or substituted C 1 -C 10 alkyl group, an unsubstituted or substituted C 1 -C 10 alkoxy group, an unsubstituted or substituted aromatic group or an unsubstituted or substituted heteroaromatic group, wherein the aromatic group is a group which has one or more C 6 -C 30 aryl groups, wherein the heteroaromatic group is a group which has one or more C 3 -C 30 heteroaryl groups.
A thienopyridone derivative of Formula: or a pharmaceutically acceptable salt and/or solvate thereof, or a pharmaceutical composition comprising the same, for use in the treatment of diabetic nephropathy. or a pharmaceutically acceptable salt and/or solvate thereof, or a pharmaceutical composition comprising the same, for use in the treatment of diabetic nephropathy.