An auto-injector system, comprising: a measurement guide having indicia configured to measure two or more dimensions of multiple skin lesions or skin disorders of various sizes, wherein the two or more dimensions include at least a diameter and a height of the multiple skin lesions or skin disorders; and an auto-injector device comprising: a syringe; a needle (17, 120) arranged in the vicinity of a first end of the syringe; a plunger (19, 160) arranged within the syringe, wherein a volume (11, 102) within the syringe between the plunger (19, 160) and the needle (17, 120) accommodates medicine, such that movement of the plunger (19, 160) toward the needle (17, 120) dispenses an amount of the medicine through the needle (17, 160); and a selection assembly (21, 110, 132) configurable by a user to adjust the amount of medicine dispensed by the auto-injector device and a depth to which the medicine is administered, the selection assembly (21, 110, 132) having selectors (23, 25, 27, 35, 37, 39, 116, 134) directly corresponding to different measurements from the indicia, wherein the selectors (23, 25, 27, 35, 37, 39, 116, 134) are selectively operable by the user and configured to adjust the amount and the depth based on the measured two or more dimensions of a skin lesion or a skin disorder. a measurement guide having indicia configured to measure two or more dimensions of multiple skin lesions or skin disorders of various sizes, wherein the two or more dimensions include at least a diameter and a height of the multiple skin lesions or skin disorders; and an auto-injector device comprising: a syringe; a needle (17, 120) arranged in the vicinity of a first end of the syringe; a plunger (19, 160) arranged within the syringe, wherein a volume (11, 102) within the syringe between the plunger (19, 160) and the needle (17, 120) accommodates medicine, such that movement of the plunger (19, 160) toward the needle (17, 120) dispenses an amount of the medicine through the needle (17, 160); and a selection assembly (21, 110, 132) configurable by a user to adjust the amount of medicine dispensed by the auto-injector device and a depth to which the medicine is administered, the selection assembly (21, 110, 132) having selectors (23, 25, 27, 35, 37, 39, 116, 134) directly corresponding to different measurements from the indicia, a syringe; a needle (17, 120) arranged in the vicinity of a first end of the syringe; a plunger (19, 160) arranged within the syringe, wherein a volume (11, 102) within the syringe between the plunger (19, 160) and the needle (17, 120) accommodates medicine, such that movement of the plunger (19, 160) toward the needle (17, 120) dispenses an amount of the medicine through the needle (17, 160); and a selection assembly (21, 110, 132) configurable by a user to adjust the amount of medicine dispensed by the auto-injector device and a depth to which the medicine is administered, the selection assembly (21, 110, 132) having selectors (23, 25, 27, 35, 37, 39, 116, 134) directly corresponding to different measurements from the indicia, wherein the selectors (23, 25, 27, 35, 37, 39, 116, 134) are selectively operable by the user and configured to adjust the amount and the depth based on the measured two or more dimensions of a skin lesion or a skin disorder.