A compound of formula or a pharmaceutically acceptable salt thereof, wherein p is 1 or 2; ----- is a single or double bond; m is 1; R 1 is selected from aryl and -NR q R q', wherein R q and R q' are independently selected from hydrogen, alkyl, and phenyl wherein the phenyl is optionally fused to a five- or six-membered heterocyclic ring containing two oxygen atoms and wherein the phenyl is optionally substituted with one, two, or three groups independently selected from alkoxy, alkyl, halo, and haloalkyl; or, wherein R q and R q', together with the nitrogen atom to which they are attached, form a five membered ring optionally fused to a phenyl ring, wherein the phenyl ring is optionally substituted with one, two, or three groups independently selected from alkoxy, alkyl, halo, and haloalkyl; R x is selected from methyl and ethyl; R y and R z are independently selected from hydrogen and hydroxy; provided that when ----- is a double bond, R y and R z are each hydrogen; R 2 is selected from hydrogen, alkyl, halo, haloalkoxy, haloalkyl, and hydroxyalkyl; and R 3 is selected from hydrogen, alkoxyalkoxycarbonyl, alkoxycarbonyl, alkylaminocarbonyl, alkylcarbonyl, cycloalkylalkoxycarbonyl, cycloalkylcarbonyl, cycloalkyloxycarbonyl, deuteroalkoxycarbonyl, deuterohaloalkoxycarbonyl, dialkylaminocarbonyl, dialkylaminocarbonylcarbonyl, haloalkoxycarbonyl, haloalkylaminocarbonyl, haloalkylcarbonyl, heterocyclylcarbonyl, heterocyclyloxycarbonyl, phenylcarbonyl, and phenyloxycarbonyl, wherein the cycloalkyl part of the cycloalkylalkoxycarbonyl, the cycloalkylcarbonyl, and the cycloalkyloxycarbonyl, the heterocyclyl part of the heterocyclylcarbonyl and the heterocyclyloxycarbonyl, and the phenyl part of the phenylcarbonyl and the phenyloxycarbonyl, is optionally substituted with one, two, or three groups independently selected from alkyl, alkylamino, alkylcarbonyl, cycloalkyl, dialkylamino, halo, haloalkoxy, and haloalkyl. p is 1 or 2; ----- is a single or double bond; m is 1; R 1 is selected from aryl and -NR q R q', wherein R q and R q' are independently selected from hydrogen, alkyl, and phenyl wherein the phenyl is optionally fused to a five- or six-membered heterocyclic ring containing two oxygen atoms and wherein the phenyl is optionally substituted with one, two, or three groups independently selected from alkoxy, alkyl, halo, and haloalkyl; or, wherein R q and R q', together with the nitrogen atom to which they are attached, form a five membered ring optionally fused to a phenyl ring, wherein the phenyl ring is optionally substituted with one, two, or three groups independently selected from alkoxy, alkyl, halo, and haloalkyl; R x is selected from methyl and ethyl; R y and R z are independently selected from hydrogen and hydroxy; provided that when ----- is a double bond, R y and R z are each hydrogen; R 2 is selected from hydrogen, alkyl, halo, haloalkoxy, haloalkyl, and hydroxyalkyl; and R 3 is selected from hydrogen, alkoxyalkoxycarbonyl, alkoxycarbonyl, alkylaminocarbonyl, alkylcarbonyl, cycloalkylalkoxycarbonyl, cycloalkylcarbonyl, cycloalkyloxycarbonyl, deuteroalkoxycarbonyl, deuterohaloalkoxycarbonyl, dialkylaminocarbonyl, dialkylaminocarbonylcarbonyl, haloalkoxycarbonyl, haloalkylaminocarbonyl, haloalkylcarbonyl, heterocyclylcarbonyl, heterocyclyloxycarbonyl, phenylcarbonyl, and phenyloxycarbonyl, wherein the cycloalkyl part of the cycloalkylalkoxycarbonyl, the cycloalkylcarbonyl, and the cycloalkyloxycarbonyl, the heterocyclyl part of the heterocyclylcarbonyl and the heterocyclyloxycarbonyl, and the phenyl part of the phenylcarbonyl and the phenyloxycarbonyl, is optionally substituted with one, two, or three groups independently selected from alkyl, alkylamino, alkylcarbonyl, cycloalkyl, dialkylamino, halo, haloalkoxy, and haloalkyl.