mhurhangee/ep-ind-claims huggingface dataset:
A method for in vitro determining generation of a haemostasis factor in a test sample comprising determining the amount of said haemostasis factor generated using a chemiluminescent substrate that is specific for said haemostasis factor, wherein a luminescent molecule is liberated from said chemiluminescent substrate by said haemostasis factor which luminescent molecule is subsequently converted to produce a detectable light quant, wherein said haemostasis factor is thrombin and wherein the chemiluminescent substrate is a substrate selected from the group consisting of: - RO-[CH 2 CH 2 O] n -(Sp)-Gly-Gly-Arg-aminoluciferin and RO-[CH 2 CH 2 O] n -(Sp)-beta-Ala-Gly-Arg-aminoluciferin, wherein R is H or C 1 -C 6 alkyl, n is an integer in the range of 1-10, Sp is an optional spacer moiety [CH 2] m C=O, wherein m is an integer in the range from 1-6, - a salt of the substrate here above, preferably the TFA salt. - RO-[CH 2 CH 2 O] n -(Sp)-Gly-Gly-Arg-aminoluciferin and RO-[CH 2 CH 2 O] n -(Sp)-beta-Ala-Gly-Arg-aminoluciferin, wherein R is H or C 1 -C 6 alkyl, n is an integer in the range of 1-10, Sp is an optional spacer moiety [CH 2] m C=O, wherein m is an integer in the range from 1-6, - a salt of the substrate here above, preferably the TFA salt.
An ether represented by the following chemical formula: in said chemical formula, R 4 is a straight chain or branched alkyl group having 1 - 12 carbon atoms, a straight chain or branched alkenyl group having 2 - 12 carbon atoms, a straight chain or branched alkynyl group having 2 - 12 carbon atoms, an aryl group having 5 - 24 carbon atoms, a straight chain or branched arylalkyl group having 6 - 30 carbon atoms, a cycloalkyl group having 3 - 24 carbon atoms, a cycloalkenyl group having 3 - 24 carbon atoms, a straight chain or branched cycloalkylalkyl group having 4 - 30 carbon atoms, a straight chain or branched cyclylalkyl group having 4 - 30 carbon atoms, or a straight chain or branched alkoxyalkyl group having 2 - 30 carbon atoms, n is 1, L 1 is an ethylene group (-CH 2 CH 2 -), and [D 1] is a cyano group, an enantiomer thereof, a tautomer or stereoisomer thereof or a salt thereof. R 4 is a straight chain or branched alkyl group having 1 - 12 carbon atoms, a straight chain or branched alkenyl group having 2 - 12 carbon atoms, a straight chain or branched alkynyl group having 2 - 12 carbon atoms, an aryl group having 5 - 24 carbon atoms, a straight chain or branched arylalkyl group having 6 - 30 carbon atoms, a cycloalkyl group having 3 - 24 carbon atoms, a cycloalkenyl group having 3 - 24 carbon atoms, a straight chain or branched cycloalkylalkyl group having 4 - 30 carbon atoms, a straight chain or branched cyclylalkyl group having 4 - 30 carbon atoms, or a straight chain or branched alkoxyalkyl group having 2 - 30 carbon atoms, n is 1, L 1 is an ethylene group (-CH 2 CH 2 -), and [D 1] is a cyano group,
An optical particle sensor, comprising: an optical arrangement comprising at least first and second light sources (32, 34) of different first and second wavelengths; an optical detector for detecting light emitted from particles to be sensed or light from the light sources scattered by particles to be sensed; and a controller for controlling the operation of the first and second light sources, wherein the controller is adapted to: operate the first light source, and detect light scattering using the optical detector; determine when a particle reaches a target positional area based analyzing the detected scattered light; characterized in that the controller is further adapted to: in response to the particle being determined to reach the target positional area, operate the second light source with a drive signal which is at least 2 times the maximum permitted continuous drive signal to provide a pulse of light with a duty cycle of less than 20%; and detect light emitted from the particle in response to the pulse of light using the same optical detector. an optical arrangement comprising at least first and second light sources (32, 34) of different first and second wavelengths; an optical detector for detecting light emitted from particles to be sensed or light from the light sources scattered by particles to be sensed; and a controller for controlling the operation of the first and second light sources, wherein the controller is adapted to: operate the first light source, and detect light scattering using the optical detector; determine when a particle reaches a target positional area based analyzing the detected scattered light; operate the first light source, and detect light scattering using the optical detector; determine when a particle reaches a target positional area based analyzing the detected scattered light; characterized in that the controller is further adapted to: in response to the particle being determined to reach the target positional area, operate the second light source with a drive signal which is at least 2 times the maximum permitted continuous drive signal to provide a pulse of light with a duty cycle of less than 20%; and detect light emitted from the particle in response to the pulse of light using the same optical detector. in response to the particle being determined to reach the target positional area, operate the second light source with a drive signal which is at least 2 times the maximum permitted continuous drive signal to provide a pulse of light with a duty cycle of less than 20%; and detect light emitted from the particle in response to the pulse of light using the same optical detector.
An ejection mechanism, in particular for movable furniture parts, having a curve guide (7, 7'", 7"", 108), along which a driver (11", 11"', 11"", 111) is movable, the driver (11", 11"', 11"", 111) being pre-tensioned in one direction by at least one force accumulator (8, 8', 112), and being able to be latched on the curve guide (7, 7'", 7"", 108) with tensioned force accumulator (8, 8', 112) in a closed position, and an activator (5", 5'", 5"", 106), which can be coupled to the driver (11", 11'", 11"", 111) at least in the closed position,, whereby a ratchet (41, 81; 114, 115) is provided, whereby the ratchet (41, 81; 114, 115) can pass the driver (11", 11'", 11"", 111) in an opening direction and the ratchet (41, 81) can be coupled on in the opposing closing direction, in order to move the driver (11", 11'", 11"", 111) in the closing direction, characterized in that the ratchet (41, 81; 114, 115) is mounted so it is pivotable, and can be latched behind the driver (11", 11'", 11"", 111) during an opening movement or the activator (5", 5'", 5"", 116) comprises a displaceable or pivotable part, which can be latched behind the ratchet (41, 81) during an opening movement.
A phosphono paraffin represented by formula: wherein: each instance of R 3 is independently -H or each instance of R 1 and R 2 is independently C 1-20 alkyl, C 3-20 cycloalkyl, or aryl; n is an integer between 4 and 22; and the number of instances where R 3 is of formula is between 2 and 8. each instance of R 3 is independently -H or each instance of R 1 and R 2 is independently C 1-20 alkyl, C 3-20 cycloalkyl, or aryl; n is an integer between 4 and 22;
A circuit for an access controller of a communication network configured for: - controlling a communication ongoing over the network according to a first service offered over the network, using a first configuration of resources of the network; - receiving an information relating to the traffic load on the network; - adapting, based on the traffic load, the first service into a second service; and - transmitting a request to an access controller of the network, responsive to the adaptation of the first service, for assigning additional resources to the first configuration and/or decreasing resources of the first configuration so as to provide a second configuration adapted to the second service; wherein the adaptation of the first service is applied to a number of communications proportional to a bandwidth occupation, when said bandwidth occupation is greater than a threshold (TRESH1). - controlling a communication ongoing over the network according to a first service offered over the network, using a first configuration of resources of the network; - receiving an information relating to the traffic load on the network; - adapting, based on the traffic load, the first service into a second service; and - transmitting a request to an access controller of the network, responsive to the adaptation of the first service, for assigning additional resources to the first configuration and/or decreasing resources of the first configuration so as to provide a second configuration adapted to the second service;
A computer-implemented method for training a deep network, comprising: calculating an intermediate weight based on an existing quantized weight of a layer of the deep network and an existing quantized residual parameter; deriving an updated weight by quantizing the intermediate weight, wherein the updated weight is a quantized quantity; and generating an updated residual parameter using the intermediate weight and the updated weight, wherein generating the updated residual parameter comprises scaling an intermediate residual parameter with the updated weight and quantizing the scaled intermediate residual parameter to derive the updated residual parameter according to r t + 1 = q r w ̃ t + 1 − w t + 1 w t + 1 if w t + 1 ≠ 0 = 0 else with r t +1 denoting the updated residual parameter, w̃ t +1 denoting the intermediate weight, w t +1 denoting the updated weight and q r denoting a quantization, and wherein scaling the intermediate residual parameter comprises performing a bit shift operation on the intermediate residual. calculating an intermediate weight based on an existing quantized weight of a layer of the deep network and an existing quantized residual parameter; deriving an updated weight by quantizing the intermediate weight, wherein the updated weight is a quantized quantity; and generating an updated residual parameter using the intermediate weight and the updated weight, wherein generating the updated residual parameter comprises scaling an intermediate residual parameter with the updated weight and quantizing the scaled intermediate residual parameter to derive the updated residual parameter according to r t + 1 = q r w ̃ t + 1 − w t + 1 w t + 1 if w t + 1 ≠ 0 = 0 else with r t +1 denoting the updated residual parameter, w̃ t +1 denoting the intermediate weight, w t +1 denoting the updated weight and q r denoting a quantization, and wherein scaling the intermediate residual parameter comprises performing a bit shift operation on the intermediate residual.
An integrated injection system, the system comprising an injection device comprising a drug delivery portion and a data transmitter, and a communication device that is external to the injection device, wherein the injection device further comprises a data capture module including at least one sensor, the module being configured to sense information about at least one of a physical condition and a behavior of a patient during an injection event by the at least one sensor, wherein the data transmitter is configured to be in electronic communication with the communication device, wherein the data transmitter is configured to transmit at least a portion of the sensed information to the communication device, wherein the injection device further comprises an external housing enclosing the drug delivery portion and the data transmitter, wherein the drug delivery portion includes a reservoir containing a pharmaceutical agent to be delivered to the patient, wherein the drug delivery portion comprises a needle, wherein the at least one sensor is located on a portion of the needle which is intended to be positioned inside the body of the patient during the injection event, wherein the needle is in fluid communication with the reservoir and extendable through at least a portion of the external housing characterized in that the reservoir is formed within a substrate layer of the drug delivery portion, and the reservoir includes a circular labyrinth. wherein the injection device further comprises a data capture module including at least one sensor, the module being configured to sense information about at least one of a physical condition and a behavior of a patient during an injection event by the at least one sensor, wherein the data transmitter is configured to be in electronic communication with the communication device, wherein the data transmitter is configured to transmit at least a portion of the sensed information to the communication device, wherein the injection device further comprises an external housing enclosing the drug delivery portion and the data transmitter, wherein the drug delivery portion includes a reservoir containing a pharmaceutical agent to be delivered to the patient, wherein the drug delivery portion comprises a needle, wherein the at least one sensor is located on a portion of the needle which is intended to be positioned inside the body of the patient during the injection event, wherein the needle is in fluid communication with the reservoir and extendable through at least a portion of the external housing characterized in that the reservoir is formed within a substrate layer of the drug delivery portion, and the reservoir includes a circular labyrinth.
A method for providing secondary content to accompany a primary content item, the method comprising: receiving, by a first content-selection module, information associated with a first secondary content item, the associated information comprising a result of a selection process performed by a second content-selection module distinct from the first content-selection module, the selection process using a first media analysis of one or more of closed caption information, video images, and accompanying audio of the primary content; analyzing, by the first content-selection module, the associated information, wherein the analyzing comprises machine learning of one or more content-selection criteria associated with selection by the second content-selection module of the first secondary content item, and wherein a result of the analyzing is based, at least in part, on the result of the selection process performed by the second content-selection module; based, at least in part, on the analyzing, modifying, by the first content-selection module, a set of content-selection criteria for secondary content, wherein the modified set of content-selection criteria is based at least in part on a second media analysis of one or more of closed caption information, video images, and accompanying audio of the first secondary content item; based, at least in part, on the modified set of content-selection criteria, preparing, by the first content-selection module, a stream of second secondary content items; and presenting the stream of second secondary content items. receiving, by a first content-selection module, information associated with a first secondary content item, the associated information comprising a result of a selection process performed by a second content-selection module distinct from the first content-selection module, the selection process using a first media analysis of one or more of closed caption information, video images, and accompanying audio of the primary content; analyzing, by the first content-selection module, the associated information, wherein the analyzing comprises machine learning of one or more content-selection criteria associated with selection by the second content-selection module of the first secondary content item, and wherein a result of the analyzing is based, at least in part, on the result of the selection process performed by the second content-selection module; based, at least in part, on the analyzing, modifying, by the first content-selection module, a set of content-selection criteria for secondary content, wherein the modified set of content-selection criteria is based at least in part on a second media analysis of one or more of closed caption information, video images, and accompanying audio of the first secondary content item; based, at least in part, on the modified set of content-selection criteria, preparing, by the first content-selection module, a stream of second secondary content items; and presenting the stream of second secondary content items.
A method for producing butadiene-styrene block copolymers by copolymerization of styrene and butadiene in a hydrocarbon solvent in the presence of an organolithium initiator and a modifier, followed by treatment of "live" polymer chains with a coupling agent, characterized in that in step (i) styrene polymerization is carried out in the presence of n-butyllithium and a modifier selected from the group consisting of tetrahydrofuran and ethylene glycol ethylbutyl ether to produce a polystyrene block of "living" polystyryllithium, and in step (ii) butadiene is added to the reaction mixture obtained in step (i), and synthesis of a polybutadiene block is carried out in the presence of a diethylene glycol dimethyl ether (diglyme) modifier, wherein said modifier is added after the beginning of the butadiene polymerization to produce "living" polystyrene-polybutadienyllithium block copolymer.
A process for preparing an alkyl aryl carbonate and a diaryl carbonate, comprising: reacting a dialkyl carbonate and an aromatic hydroxy compound in a production column (200,300) to form the alkyl aryl carbonate and the diaryl carbonate; directing a bottom stream of the production column to a reboiler (205,305), wherein the bottom stream comprises the alkyl aryl carbonate and the diaryl carbonate; heating the bottom stream in the reboiler (205,305) with heat from an overhead stream of the production column (200,300) to result in a heated bottom stream; directing a first portion of the heated bottom stream back into the production column (200,300), wherein the first portion comprises the aromatic hydroxy compound; and collecting the diaryl carbonate and the alkyl aryl carbonate from a second portion of the heated bottom stream. reacting a dialkyl carbonate and an aromatic hydroxy compound in a production column (200,300) to form the alkyl aryl carbonate and the diaryl carbonate; directing a bottom stream of the production column to a reboiler (205,305), wherein the bottom stream comprises the alkyl aryl carbonate and the diaryl carbonate; heating the bottom stream in the reboiler (205,305) with heat from an overhead stream of the production column (200,300) to result in a heated bottom stream; directing a first portion of the heated bottom stream back into the production column (200,300), wherein the first portion comprises the aromatic hydroxy compound; and collecting the diaryl carbonate and the alkyl aryl carbonate from a second portion of the heated bottom stream.
Method for establishing a fluid conveying parameter of a fluid conveying apparatus, in particular for establishing a volume flow, comprising the steps of: - establishing excitement information for a mechanical excitation of at least one fluid conveying element of the fluid conveying apparatus in at least one spatial direction by means of at least a first sensor device, wherein one or more vibrations of the fluid conveying element is/are provided as a variable of the mechanical excitation, - providing operating information items, comprising at least one value of an operating variable (4b, 4c) of the fluid conveying apparatus by means of a provision device, - analysing the information items (3a, 3b) provided and established, - establishing the fluid conveying parameter (2, 10), in particular of the volume flow, of the fluid conveying apparatus based on the analysed information items. - establishing excitement information for a mechanical excitation of at least one fluid conveying element of the fluid conveying apparatus in at least one spatial direction by means of at least a first sensor device, wherein one or more vibrations of the fluid conveying element is/are provided as a variable of the mechanical excitation, - providing operating information items, comprising at least one value of an operating variable (4b, 4c) of the fluid conveying apparatus by means of a provision device, - analysing the information items (3a, 3b) provided and established, - establishing the fluid conveying parameter (2, 10), in particular of the volume flow, of the fluid conveying apparatus based on the analysed information items.
Pharmaceutical composition characterized by comprising a synergic combination of Finasteride and Alfuzosine, together with pharmaceutically acceptable excipients, which are formulated in a single dosage unit to be orally administered once a day, characterized in that Finasteride is present in the formulation in a concentration of 5 mg and Alfuzosine is present in the formulation in a concentration of 5.0 mg per dose unit.
Composition comprising: - for 100 parts by weight of at least one acrylic adhesive, - from 0.01 to 25 parts by weight of particles of a cross-linked polymer having a carboxylate-group density between 2.0 and 12.0meq/g and an average pore size between 0.005 and 1.0μm determined as indicated in the specification. - for 100 parts by weight of at least one acrylic adhesive, - from 0.01 to 25 parts by weight of particles of a cross-linked polymer having a carboxylate-group density between 2.0 and 12.0meq/g and an average pore size between 0.005 and 1.0μm determined as indicated in the specification.
A prosthetic heart valve having a compressed delivery configuration and an expanded deployed configuration, the prosthetic heart valve comprising: a self-expanding stent body having a tubular body and a cuff integral with and extending from the tubular body, a cuff covering being disposed on the cuff; characterized by a leaflet structural support disposed within a lumen of the tubular body and attached to the stent body, the leaflet structural support being configured to be compressed when the prosthetic heart valve is in the compressed delivery configuration and to expand to the expanded configuration when the prosthetic heart valve is deployed from a deployment catheter; and a prosthetic leaflet structure attached to the leaflet structural support, the cuff including a plurality of radially extending loops collectively defining a collar shape and defining circumferential spaces between adjacent loops, the collar having a distal-facing side and a proximal-facing side, wherein the leaflet structural support includes three junctions that are not directly connected to the stent body, and three arched wires that are directly connected to the stent body, so that the three junctions of the leaflet structural support are independently moveable with respect to the stent body, wherein the leaflet structural support is housed within the stent body in both the compressed delivery configuration and in the expanded deployed configuration. a self-expanding stent body having a tubular body and a cuff integral with and extending from the tubular body, a cuff covering being disposed on the cuff; characterized by a leaflet structural support disposed within a lumen of the tubular body and attached to the stent body, the leaflet structural support being configured to be compressed when the prosthetic heart valve is in the compressed delivery configuration and to expand to the expanded configuration when the prosthetic heart valve is deployed from a deployment catheter; and a prosthetic leaflet structure attached to the leaflet structural support, the cuff including a plurality of radially extending loops collectively defining a collar shape and defining circumferential spaces between adjacent loops, the collar having a distal-facing side and a proximal-facing side, wherein the leaflet structural support includes three junctions that are not directly connected to the stent body, and three arched wires that are directly connected to the stent body, so that the three junctions of the leaflet structural support are independently moveable with respect to the stent body, wherein the leaflet structural support is housed within the stent body in both the compressed delivery configuration and in the expanded deployed configuration.