A surgical stapling device comprising: an elongate body; and a tool assembly supported on a distal portion of the elongate body, the tool assembly including a cartridge assembly (104, 204) and an anvil assembly (102, 202), the cartridge and anvil assemblies being movable in relation to each other between spaced and approximated positions; the cartridge assembly including: a staple cartridge (106, 206) supporting a plurality of staples; a support plate (114, 214) comprising a resilient protrusion (114a, 214a); wherein the surgical stapling device further comprises a clamp member (118, 218) configured to engage with the anvil assembly, the clamp member having an engagement member (166, 264) and a body supporting a knife (152, 252); and an actuation sled (120, 220) including a cam member (170a, 170b, 270a, 270b) and a stop configured to engage with the engagement member, wherein the stop includes a distal ramped surface such that the engagement member is configured to move from a distal side of the stop to a proximal side of the stop, wherein the resilient protrusion defines a stop surface to prevent proximal movement of the actuation sled, wherein in a pre-actuated state, the clamp member and the actuation sled are positioned in a nested relationship in which the knife of the clamp member is positioned distally of a proximal end of the cam member of the actuation sled, wherein during at least a portion of a firing stroke of the surgical stapling device, the clamp member is movable to position the knife proximally of the cam member. an elongate body; and a tool assembly supported on a distal portion of the elongate body, the tool assembly including a cartridge assembly (104, 204) and an anvil assembly (102, 202), the cartridge and anvil assemblies being movable in relation to each other between spaced and approximated positions; the cartridge assembly including: a staple cartridge (106, 206) supporting a plurality of staples; a support plate (114, 214) comprising a resilient protrusion (114a, 214a); wherein the surgical stapling device further comprises a clamp member (118, 218) configured to engage with the anvil assembly, the clamp member having an engagement member (166, 264) and a body supporting a knife (152, 252); and an actuation sled (120, 220) including a cam member (170a, 170b, 270a, 270b) and a stop configured to engage with the engagement member, wherein the stop includes a distal ramped surface such that the engagement member is configured to move from a distal side of the stop to a proximal side of the stop, wherein the resilient protrusion defines a stop surface to prevent proximal movement of the actuation sled, wherein in a pre-actuated state, the clamp member and the actuation sled are positioned in a nested relationship in which the knife of the clamp member is positioned distally of a proximal end of the cam member of the actuation sled, wherein during at least a portion of a firing stroke of the surgical stapling device, the clamp member is movable to position the knife proximally of the cam member. a staple cartridge (106, 206) supporting a plurality of staples; a support plate (114, 214) comprising a resilient protrusion (114a, 214a); wherein the surgical stapling device further comprises a clamp member (118, 218) configured to engage with the anvil assembly, the clamp member having an engagement member (166, 264) and a body supporting a knife (152, 252); and an actuation sled (120, 220) including a cam member (170a, 170b, 270a, 270b) and a stop configured to engage with the engagement member, wherein the stop includes a distal ramped surface such that the engagement member is configured to move from a distal side of the stop to a proximal side of the stop, wherein the resilient protrusion defines a stop surface to prevent proximal movement of the actuation sled, wherein in a pre-actuated state, the clamp member and the actuation sled are positioned in a nested relationship in which the knife of the clamp member is positioned distally of a proximal end of the cam member of the actuation sled, wherein during at least a portion of a firing stroke of the surgical stapling device, the clamp member is movable to position the knife proximally of the cam member.