mhurhangee/ep-ind-claims huggingface dataset:
A bioassay method wherein the presence of a specific soluble antibody of an animal, including human, in a sample comprising a bodily fluid of said animal is qualitatively and/or quantitatively determined, said method employing a) a first group including an energy donor, and b) a second group including an energy acceptor or quencher, wherein i) said first group or said second group comprises an antigen of said soluble antibody, and ii) said second group or said first group, respectively, comprises a fragment antigen-binding (Fab) binding moiety coupled to said energy donor, or said energy acceptor, including quencher, respectively, said moiety being capable of binding to a Fab region of antibodies of said animal, wherein said energy donor and said energy acceptor or quencher form an energy transfer pair capable of energy transfer; and the FBM is selected from the group consisting of protein L, recombinant protein L, Ch1 binding protein or at least one domain or fragment thereof with the capability of binding to light chain, heavy chain, both light and heavy chain, the interface between the light chain and the heavy chain, or the surface formed of the light and the heavy chain in the Fab region of Ig molecule, preferably the FBM is recombinant protein L or at least one domain or fragment thereof with the capability of binding to light chain, heavy chain, both light and heavy chain, the interface between the light chain and the heavy chain, or the surface formed of the light and the heavy chain in the Fab region of Ig molecule. a) a first group including an energy donor, and b) a second group including an energy acceptor or quencher, i) said first group or said second group comprises an antigen of said soluble antibody, and ii) said second group or said first group, respectively, comprises a fragment antigen-binding (Fab) binding moiety coupled to said energy donor, or said energy acceptor, including quencher, respectively, said moiety being capable of binding to a Fab region of antibodies of said animal,
A fastening system for detachable mounting of covering components, such as panels, on other components such as automotive body parts, with at least one spacer which has a spacer body of differently predefinable design height, which spacer can be secured by means of a fastening means on the covering component on its one side and is provided with a hook-and-loop fastening part on its opposite side, which hook-and-loop fastening part can be detachably engaged with a corresponding hook-and-loop fastening part which can be secured on the other component, characterised in that a flat mesh which enlarges the connection area between covering component and spacer is connected to at least one edge of the side of the spacer body to be connected to the covering component, and that the mesh is integrally moulded on the spacer body in one piece.
A laser system for ophthalmic surgery, comprising: a laser source to produce a surgical pulsed laser beam; an XY scanner to scan the surgical pulsed laser beam in XY transverse directions to the optical axis; a Z scanner (250,450), to scan the XY scanned laser beam along a Z axis, the Z scanner comprising a numerical aperture controller configured to modify a numerical aperture of the scanned laser beam; an objective, to focus the XYZ scanned beam into a focal spot in a target region; and a computational controller to use a computational process only to control at least one of the Z scanner and the XY scanner, to control an optical distortion of the focused scanned beam, the computational controller configured to compute scanner coordinates of at least one of the Z scanner and the XY scanner that correspond to focal coordinates along a scanning pattern via a transfer matrix algorithm to reduce optical distortion at a focal spot of the laser beam; and characterized in that the Z scanner is further configured to modify the numerical aperture of the scanned laser beam to a predetermined numerical aperture NA as a function of a Z focal depth, thereby generating a diffraction limited laser beam a laser source to produce a surgical pulsed laser beam; an XY scanner to scan the surgical pulsed laser beam in XY transverse directions to the optical axis; a Z scanner (250,450), to scan the XY scanned laser beam along a Z axis, the Z scanner comprising a numerical aperture controller configured to modify a numerical aperture of the scanned laser beam; an objective, to focus the XYZ scanned beam into a focal spot in a target region; and a computational controller to use a computational process only to control at least one of the Z scanner and the XY scanner, to control an optical distortion of the focused scanned beam, the computational controller configured to compute scanner coordinates of at least one of the Z scanner and the XY scanner that correspond to focal coordinates along a scanning pattern via a transfer matrix algorithm to reduce optical distortion at a focal spot of the laser beam; and characterized in that the Z scanner is further configured to modify the numerical aperture of the scanned laser beam to a predetermined numerical aperture NA as a function of a Z focal depth, thereby generating a diffraction limited laser beam
A fluid characterization measuring instrument, comprising: a capillary tube sample cell for a bulk complex sample fluid, the capillary tube sample cell having a diameter of 1.5 mm or less, a coherent light source positioned to illuminate the bulk complex sample fluid in the sample cell, a fibre having a first end positioned to receive backscattered light from the sample after it has interacted with the sample, a first photon-counting detector positioned to receive the backscattered light from a second end of the fibre, a correlator configured to apply a correlation function to a signal from the first photon-counting detector and to derive an elastic modulus and a viscous modulus of the sample fluid from the correlation function based on single scattering analysis. a capillary tube sample cell for a bulk complex sample fluid, the capillary tube sample cell having a diameter of 1.5 mm or less, a coherent light source positioned to illuminate the bulk complex sample fluid in the sample cell, a fibre having a first end positioned to receive backscattered light from the sample after it has interacted with the sample, a first photon-counting detector positioned to receive the backscattered light from a second end of the fibre, a correlator configured to apply a correlation function to a signal from the first photon-counting detector and to derive an elastic modulus and a viscous modulus of the sample fluid from the correlation function based on single scattering analysis.
A method for transmitting control information, characterized by comprising: categorizing, by a base station, downlink control information into common control information and dedicated control information; extending, by the base station, a physical broadcast channel: dividing a common control channel domain into a plurality of narrowband sub-control channel domains by adding a position identifier used for indicating a time-frequency position of the common control channel domain; before a connection between the base station and a narrowband user terminal is established, sending, by the base station, according to the position identifier, the common control information in each sub-control channel domain of the common control channel domain; allocating, by the base station, a random access resource dedicated for the narrowband user terminal and notifying the narrowband user terminal in system information; and after the connection is established, selecting, by the base station, according to a channel state of each sub-control channel domain, a sub-control channel domain with a channel state that complies with a set standard for sending the dedicated control information, and sending a channel instruction, wherein the set standard comprises a channel priority, a channel connection quality, and/or a channel occupation condition; wherein the channel instruction is information used by the base station to instruct, according to the channel state of each sub-control channel domain, the narrowband user terminal to select a sub-control channel domain that complies with the set standard. categorizing, by a base station, downlink control information into common control information and dedicated control information; extending, by the base station, a physical broadcast channel: dividing a common control channel domain into a plurality of narrowband sub-control channel domains by adding a position identifier used for indicating a time-frequency position of the common control channel domain; before a connection between the base station and a narrowband user terminal is established, sending, by the base station, according to the position identifier, the common control information in each sub-control channel domain of the common control channel domain; allocating, by the base station, a random access resource dedicated for the narrowband user terminal and notifying the narrowband user terminal in system information; and after the connection is established, selecting, by the base station, according to a channel state of each sub-control channel domain, a sub-control channel domain with a channel state that complies with a set standard for sending the dedicated control information, and sending a channel instruction, wherein the set standard comprises a channel priority, a channel connection quality, and/or a channel occupation condition; wherein the channel instruction is information used by the base station to instruct, according to the channel state of each sub-control channel domain, the narrowband user terminal to select a sub-control channel domain that complies with the set standard.
A transgenic laboratory rodent, which comprises an endogenous immunoglobulin heavy-chain locus comprising the replacement of its mu heavy-chain switch sequence Sμ by a human transgenic DNA construct comprising respectively from its 5' to its 3'end, at least: (a) a first site-specific recombination sequence, a human immunoglobulin mu heavy-chain constant gene Cμ or a functional fragment thereof comprising at least human CH1, CH2, CH3 and CH4 exons and human membrane M1 and M2 exons, and a second site-specific recombination sequence, said first and said second recombination sequences being in the same orientation and capable of site-specific recombination, and (b) a human immunoglobulin epsilon heavy-chain constant gene Cε or a functional fragment thereof comprising at least human CH1, CH2, CH3 and CH4 exons and human membrane M1 and M2 exons, and wherein said transgenic rodent comprises endogenous B-cells which produce chimeric human immunoglobulin M (IgM) class antibodies and no endogenous IgM antibodies from said transgenic rodent, and wherein said B-cells switch chimeric human antibodies class production from immunoglobulin M to immunoglobulin E (IgE), following site-specific recombination between said first and second site-specific recombination sequences. (a) a first site-specific recombination sequence, a human immunoglobulin mu heavy-chain constant gene Cμ or a functional fragment thereof comprising at least human CH1, CH2, CH3 and CH4 exons and human membrane M1 and M2 exons, and a second site-specific recombination sequence, said first and said second recombination sequences being in the same orientation and capable of site-specific recombination, and (b) a human immunoglobulin epsilon heavy-chain constant gene Cε or a functional fragment thereof comprising at least human CH1, CH2, CH3 and CH4 exons and human membrane M1 and M2 exons, and
An inspection device for a mechanical element comprising a main axis and a side surface including screw threads, said inspection device being adapted to inspect at least part of said side surface and comprising a supporting structure suitable to support lighting means and at least one optical unit, said optical unit comprising at least one video camera and said lighting means, characterised in that said lighting means is adapted to illuminate said side surface in a grazing manner, according to lighting directions striking on said side surface and forming, with said main axis, lighting angles (α) included between 5° and 15°, and in that said optical unit is adapted to define at least one shooting beam suitable to take the image of at least one portion of said side surface frontally, according to shooting directions striking on said side surface and forming, with said main axis, shooting angles (β) included between 75° and 115°, and in that said optical unit is adapted to take the entire image of said side surface frontally and simultaneously, and said lighting means is adapted to simultaneously illuminate the whole of said side ace.
Electrotherapy device which comprises: - a plurality of active electrodes; - a return electrode; and - a plurality of voltage generators each connected to an active electrode; said device comprising a voltage generator controller which has means for monitoring and/or varying the voltage supplied to each of the active electrodes independently; characterised in that the voltage in common mode at the common resistance is reduced by modifying the phase of the currents of the electrodes or by modifying the voltage of at least one of the generators iteratively until the required current is obtained at each of the electrodes. - a plurality of active electrodes; - a return electrode; and - a plurality of voltage generators each connected to an active electrode;
A method for attenuating noise in marine seismic signals, comprising: cross ghosting pressure responsive marine seismic signals acquired by deploying pressure responsive sensors in a body of water and contemporaneously acquired motion responsive marine seismic signals acquired by deploying particle motion responsive sensors in the body of water, the signals acquired in response to actuation of a seismic energy source in the body of water; determining a difference between the cross ghosted signals; and using the difference to attenuate (210; 306) substantially horizontally propagating noise in at least one of the pressure responsive signals and the motion responsive signals. cross ghosting pressure responsive marine seismic signals acquired by deploying pressure responsive sensors in a body of water and contemporaneously acquired motion responsive marine seismic signals acquired by deploying particle motion responsive sensors in the body of water, the signals acquired in response to actuation of a seismic energy source in the body of water; determining a difference between the cross ghosted signals; and using the difference to attenuate (210; 306) substantially horizontally propagating noise in at least one of the pressure responsive signals and the motion responsive signals.
A fishing bag comprising: a handle including a pair of end portions (40, 42) attached to a bag main body; and a shoulder belt including a pair of end portions attached to the bag main body, wherein the shoulder belt is configured to be held between the bag main body and the handle, and wherein the handle includes a detachable attachment portion, said fishing bag being characterized in that the detachable attachment portion is detachably fixed to the bag main body, and the shoulder belt is configured to be held between the detachable attachment portion and one of the pair of end portions (40,42) of the handle. a handle including a pair of end portions (40, 42) attached to a bag main body; and a shoulder belt including a pair of end portions attached to the bag main body, wherein the shoulder belt is configured to be held between the bag main body and the handle, and wherein the handle includes a detachable attachment portion, said fishing bag being characterized in that the detachable attachment portion is detachably fixed to the bag main body, and the shoulder belt is configured to be held between the detachable attachment portion and one of the pair of end portions (40,42) of the handle.
A pharmaceutical composition consisting of: an antibiotic or a pharmaceutically acceptable salt thereof, wherein the antibiotic comprises 100 mg of minocycline; an immunosuppressive or a pharmaceutically acceptable salt thereof, wherein the immunosuppressive comprises 2 mg of sirolimus; a statin or a pharmaceutically acceptable salt thereof, wherein the statin consists of 20 mg atorvastatin; and one or more pharmaceutically acceptable carriers, diluents, or excipients.
A control apparatus for an agricultural working machine, wherein a control sequence is associated with the agricultural working machine, wherein a processor device is provided for determining the triggerability of the control sequence based on a working machine position and area information relating to a processing field, characterised in that determining the triggerability is also based on a direction of travel of the working machine and wherein the processor device is adapted, based on the area information and the control sequence, to determine an in particular substantially rectangular admissibility area (6a-d), preferably with a triggering point (7a, 7b).
A method of preparing oligomannuronic diacids, comprising an oxidation reaction step of contacting oligomannuronic acids with a bromine-containing oxidant, wherein the bromine-containing oxidant is selected from the group consisting of bromine water, liquid bromine, hypobromous acid, hypobromite, a combination of a bromide ion source with hypochlorite, and a combination of bromine with hypochlorite, and wherein the temperature of the oxidation reaction is 10-40°C.
A lithium-ion battery comprising a cell and an electrolyte solution, the cell comprising a negative electrode sheet, wherein the negative electrode sheet comprises a negative electrode current collector, an active coating layer disposed on a surface of the negative electrode current collector, and a protective coating layer disposed on a surface of the active coating layer, the protective coating layer is a solid-state electrolyte coating layer, a molar ratio of a content of high-valence metal elements to a content of low-valence metal elements in a same type of elements in the protective coating layer is 1:0.1 to 1:1, a thickness of the solid-state electrolyte coating layer is 0.5μm to 5μm, and a solid-state electrolyte of the solid-state electrolyte coating layer is selected from one or more of Li 1+ x Al x Ti 2- x (PO 4) 3 (0<x<2) and Li 3x La 2/3-x TiO 3 (0<x<2/3).
Thin flexure joint, a) comprising a first material portion (M 1) and a second material portion (M 2) which is connected in a monolithic manner thereto by way of a thin point, b) wherein the material thickness (X 1, X 2), measured in a thickness direction, of the first and/or second material portion (M 1, M 2) decreases in a tapering zone (V 1, V 2) in a longitudinal direction, which is perpendicular to the X direction, as far as the thin point at the thin-point position (Y D) to a minimum thin-point thickness (X D), and wherein a pivot axis (W D) of the thin point extends over the width of the thin point in a width direction which runs perpendicularly to the X and Y direction, c) and wherein a cross section (Q D), which is formed in an X-Y plane (E D) through the thin point and has a section width running in the Z direction, has a cross-sectional area (A D), and d) wherein at least one aperture (U 1, U 2) is provided in at least one tapering zone (V 1, V 2), characterized in that e) a cross section (Q', Q"...) of a tapering zone (V 1, V 2) having a sectional plane (E', E"...) which runs parallel to the plane (E D) and is located through the at least one aperture (U 1, U 2) creates a cross-sectional area (A', A"...) with the section width, f) wherein the cross-sectional areas (A', A"...) formed along a portion of extent (L u) running in the Y direction have a strength which, within manufacturing tolerances, corresponds to the strength of the cross-sectional area (A D) at the thin point. a) comprising a first material portion (M 1) and a second material portion (M 2) which is connected in a monolithic manner thereto by way of a thin point, b) wherein the material thickness (X 1, X 2), measured in a thickness direction, of the first and/or second material portion (M 1, M 2) decreases in a tapering zone (V 1, V 2) in a longitudinal direction, which is perpendicular to the X direction, as far as the thin point at the thin-point position (Y D) to a minimum thin-point thickness (X D), and wherein a pivot axis (W D) of the thin point extends over the width of the thin point in a width direction which runs perpendicularly to the X and Y direction, c) and wherein a cross section (Q D), which is formed in an X-Y plane (E D) through the thin point and has a section width running in the Z direction, has a cross-sectional area (A D), and d) wherein at least one aperture (U 1, U 2) is provided in at least one tapering zone (V 1, V 2), characterized in that e) a cross section (Q', Q"...) of a tapering zone (V 1, V 2) having a sectional plane (E', E"...) which runs parallel to the plane (E D) and is located through the at least one aperture (U 1, U 2) creates a cross-sectional area (A', A"...) with the section width, f) wherein the cross-sectional areas (A', A"...) formed along a portion of extent (L u) running in the Y direction have a strength which, within manufacturing tolerances, corresponds to the strength of the cross-sectional area (A D) at the thin point.
An apparatus useful for printing, comprising: a first member including a first outer surface; a second member including a second outer surface; a belt including an inner surface and an outer surface; a first nip formed by contact between the inner surface of the belt and the second outer surface and contact between the outer surface of the belt and the first outer surface; and a stripping mechanism comprising a stripping member disposed internal to the belt, characterized in that the stripping member is configured to be positionable relative to the first nip to vary a pressure applied by the outer surface of the belt against the first outer surface downstream from the first nip, at a second nip, based on a stiffness of media to be fed through the first nip, such that the media are stripped from the outer surface of the belt after exiting from the first nip. a first member including a first outer surface; a second member including a second outer surface; a belt including an inner surface and an outer surface; a first nip formed by contact between the inner surface of the belt and the second outer surface and contact between the outer surface of the belt and the first outer surface; and a stripping mechanism comprising a stripping member disposed internal to the belt, characterized in that the stripping member is configured to be positionable relative to the first nip to vary a pressure applied by the outer surface of the belt against the first outer surface downstream from the first nip, at a second nip, based on a stiffness of media to be fed through the first nip, such that the media are stripped from the outer surface of the belt after exiting from the first nip.