A system (100, 300) for treating tissue, comprising: an applicator (104, 304) including a catheter (106, 306) and a control member (108, 308) extending therethrough, the catheter (106, 306) extending longitudinally from a proximal end to a distal end and including a lumen (132, 332) extending therethrough, the control member (108, 308) longitudinally movable relative to the catheter (106, 306) and including an abutment structure (120, 320) proximate a distal end thereof; and a clip assembly (102, 302) releasably coupleable to a distal end of the applicator (104, 304), the clip assembly (102, 302) including a pair of clip arms (110, 310), each of the clip arms extending from a proximal end to a distal end, the proximal end of each of the clip arms (110, 310) slidably received within a channel of a capsule (112, 312) and configured to be releasably coupled to the distal end of the control member (108, 308) so that the clip arms (110, 310) are movable relative to the capsule (112, 312) between a tissue receiving configuration, in which distal ends of the clip arms (110, 310) are separated from one another, and a tissue clipping configuration, in which distal ends of the clip arms are moved toward one another; the capsule (112, 312) including proximal tabs (114, 314) movable between a biased non-engaging configuration, in which the proximal tabs (114, 314) extend into the channel, and an engaging configuration, in which the proximal tabs (114, 314) extend laterally outward relative to a longitudinal axis of the capsule (112, 312) to engage an engaging portion of the catheter (106, 306), wherein the abutment structure (120, 320) maintains an engagement with the proximal tabs (114, 314), holding the proximal tabs (114, 314) in the engaging configuration, while the abutment structure (120, 320) is received within the capsule (112, 312); characterised in that the distal end of the control member (108, 308) is releasably connected to the proximal ends of the clip arms (110, 310) so that, when a proximal force on the control member (108, 308) exceeds a predetermined threshold value, the control member (108, 308) is disengaged from the clip arms (110, 310). an applicator (104, 304) including a catheter (106, 306) and a control member (108, 308) extending therethrough, the catheter (106, 306) extending longitudinally from a proximal end to a distal end and including a lumen (132, 332) extending therethrough, the control member (108, 308) longitudinally movable relative to the catheter (106, 306) and including an abutment structure (120, 320) proximate a distal end thereof; and a clip assembly (102, 302) releasably coupleable to a distal end of the applicator (104, 304), the clip assembly (102, 302) including a pair of clip arms (110, 310), each of the clip arms extending from a proximal end to a distal end, the proximal end of each of the clip arms (110, 310) slidably received within a channel of a capsule (112, 312) and configured to be releasably coupled to the distal end of the control member (108, 308) so that the clip arms (110, 310) are movable relative to the capsule (112, 312) between a tissue receiving configuration, in which distal ends of the clip arms (110, 310) are separated from one another, and a tissue clipping configuration, in which distal ends of the clip arms are moved toward one another; the capsule (112, 312) including proximal tabs (114, 314) movable between a biased non-engaging configuration, in which the proximal tabs (114, 314) extend into the channel, and an engaging configuration, in which the proximal tabs (114, 314) extend laterally outward relative to a longitudinal axis of the capsule (112, 312) to engage an engaging portion of the catheter (106, 306), wherein the abutment structure (120, 320) maintains an engagement with the proximal tabs (114, 314), holding the proximal tabs (114, 314) in the engaging configuration, while the abutment structure (120, 320) is received within the capsule (112, 312); characterised in that the distal end of the control member (108, 308) is releasably connected to the proximal ends of the clip arms (110, 310) so that, when a proximal force on the control member (108, 308) exceeds a predetermined threshold value, the control member (108, 308) is disengaged from the clip arms (110, 310).