mhurhangee/ep-ind-claims huggingface dataset:
A polymeric system for release of an active agent, having a first polymeric phase comprising polyethylene glycol and containing the active agent as a PEG-conjugated active agent, said first polymeric phase forming discrete regions of a set size range and being dispersed within a second polymeric phase comprising a cross-linked polysaccharide-phenol conjugate for release of the active agent therein.
A JAK inhibitor for use in a method of treating ulcerative colitis in a subject, the method comprising administering to the subject the JAK inhibitor in an ingestible device, wherein the ingestible device comprises: an ingestible housing comprising a reservoir having a therapeutically effective amount of the JAK inhibitor stored therein; a release mechanism having a closed state which retains the JAK inhibitor in the reservoir and an open state which allows for the release of the JAK inhibitor from the reservoir to the exterior of the device; an actuator which controls the transition of the release mechanism from the closed to the open state; a detector for detecting the location of the ingestible device in the subject's gastrointestinal tract; and a processor which is coupled to the detector and to the actuator and which triggers the actuator to cause the release mechanism to transition from its closed state to its open state to release the JAK inhibitor in the cecum when it is determined that the ingestible device is in the cecum of the subject, wherein the site of disease is in the colon, wherein determining the location of the ingestible device in the gastrointestinal tract comprises detecting a transition of the ingestible device from the ileum to the cecum. an ingestible housing comprising a reservoir having a therapeutically effective amount of the JAK inhibitor stored therein; a release mechanism having a closed state which retains the JAK inhibitor in the reservoir and an open state which allows for the release of the JAK inhibitor from the reservoir to the exterior of the device; an actuator which controls the transition of the release mechanism from the closed to the open state; a detector for detecting the location of the ingestible device in the subject's gastrointestinal tract; and a processor which is coupled to the detector and to the actuator and which triggers the actuator to cause the release mechanism to transition from its closed state to its open state to release the JAK inhibitor in the cecum when it is determined that the ingestible device is in the cecum of the subject, wherein the site of disease is in the colon, wherein determining the location of the ingestible device in the gastrointestinal tract comprises detecting a transition of the ingestible device from the ileum to the cecum.
A method for operating a fuel supply pump of a vehicle, the vehicle comprising a combustion engine system and a gearbox, the method comprising the steps of: - determining (s420; s430) values (Pb; λ) of at least one operational parameter of the combustion engine system, wherein the at least one operational parameter is a boost pressure (Pb) of the combustion engine system and/or a Lambda-value (λ) of the combustion engine system; - determining a reduction of a fuel provision rate to the combustion engine system; - determining whether a gear step change of the gearbox is at hand, on the basis of the thus determined values (Pb; λ) of the at least one operational parameter; - in case a gear step change of the gearbox is at hand, controlling operation of the fuel supply pump so as to maintain fuel supply pump speed (Prpm); and - in case a gear step change of the gearbox is not at hand, allowing a change of fuel supply pump speed (Prpm). - determining (s420; s430) values (Pb; λ) of at least one operational parameter of the combustion engine system, wherein the at least one operational parameter is a boost pressure (Pb) of the combustion engine system and/or a Lambda-value (λ) of the combustion engine system; - determining a reduction of a fuel provision rate to the combustion engine system; - determining whether a gear step change of the gearbox is at hand, on the basis of the thus determined values (Pb; λ) of the at least one operational parameter; - in case a gear step change of the gearbox is at hand, controlling operation of the fuel supply pump so as to maintain fuel supply pump speed (Prpm); and - in case a gear step change of the gearbox is not at hand, allowing a change of fuel supply pump speed (Prpm).
High-voltage DC insulator for insulating a conductor to which DC voltage is applied, comprising: a main body which runs about an axis and is composed of insulating material; and a field control electrode which runs around within the main body in the circumferential direction, wherein the field control electrode has, at least in regions, a first circumferential region and a second circumferential region which runs at a distance from the first circumferential region in the direction of the axis, so that a through-passage is formed between the first circumferential region and the second circumferential region, characterized in that the first circumferential region and/or the second circumferential region run, in axial cross section, starting from the respective axial periphery (110, 120) of the main body at least in regions so as to form an acute angle (α) in relation to the axial direction in the direction of the centre of the main body, wherein the acute angle (α) is greater than 3°. a main body which runs about an axis and is composed of insulating material; and a field control electrode which runs around within the main body in the circumferential direction, wherein the field control electrode has, at least in regions, a first circumferential region and a second circumferential region which runs at a distance from the first circumferential region in the direction of the axis, so that a through-passage is formed between the first circumferential region and the second circumferential region, characterized in that the first circumferential region and/or the second circumferential region run, in axial cross section, starting from the respective axial periphery (110, 120) of the main body at least in regions so as to form an acute angle (α) in relation to the axial direction in the direction of the centre of the main body, wherein the acute angle (α) is greater than 3°.
Object transporting device comprising a receptacle suitable for receiving at least one object, a support which can to be associated with a driving device for driving along a direction, named the longitudinal driving direction, and a connecting mechanism for connecting the receptacle to the support, this connecting mechanism being configured to: - interlock the receptacle and the support in longitudinal translation, - permit a lateral tilting of the receptacle for the purpose of laterally discharging each object carried by the receptacle, - and allow a relative displacement of the receptacle in vertical translation with respect to the support with a stroke adapted for the weighing of the receptacle and of the object(s) which it carries, characterised in that said connecting mechanism comprises at least one ball interposed and imprisoned between at least one bearing surface of the receptacle and at least one bearing surface of the support in order to be able to roll without sliding vertically on at least one of these bearing surfaces. - interlock the receptacle and the support in longitudinal translation, - permit a lateral tilting of the receptacle for the purpose of laterally discharging each object carried by the receptacle, - and allow a relative displacement of the receptacle in vertical translation with respect to the support with a stroke adapted for the weighing of the receptacle and of the object(s) which it carries,
A process for transferring polyolefin particles from a first gas-phase polymerization reactor to a second gas-phase polymerization reactor in a multistage polymerization of olefins carried out in at least two serially connected gas-phase polymerization reactors, wherein the first gas-phase reactor is a fluidized-bed reactor comprising a gas distribution grid and a settling pipe, which is integrated with its upper opening into the distribution grid and contains a densified bed of polyolefin particles which moves from top to bottom of the settling pipe, the process comprising the steps of introducing a fluid into the settling pipe in an amount that an upward stream of the fluid is induced in the bed of polyolefin particles above the fluid introduction point; withdrawing polyolefin particles from the lower end of the settling pipe; and transferring the withdrawn polyolefin particles into the second gas-phase polymerization reactor.
Clip-fixing means for fixing a hose clip on a hose end portion, having at least one clip band, which is wound tangentially in an approximately circular-ring-shaped manner around an imaginary longitudinal axis with a radial spacing, having a clamping device, and having at least one areal holding element (5, 6), which protrudes axially from the clip band, characterized in that the clip-fixing means has at least one staple-like fastening element which is separate from the holding element (5, 6), wherein the staple-like fastening element has at least two legs and a connecting web and the ends of the legs are made to penetrate through the wall of the hose end portion and, on the side directed away from the penetration side of the hose wall, are bent nearly at right angles towards one another or away from one another, and the connecting web securely clamps the at least one areal holding element (5, 6) on the wall of the hose end portion.
Tapped transformer comprising: - a transformer vessel, in which at least one winding comprising a main winding and a regulating winding with winding taps, is arranged, - an on-load tap changer for uninterrupted switching over between the winding taps of the regulating winding, comprising • a selector for power-free selection of the respective winding tap which is to be switched over to and • a load changeover switch for the actual switching over from the connected to the new, preselected winding tap, wherein - the selector and the load changeover switch are arranged spatially separately from one another, characterised in that - the selector is arranged directly at the winding taps of the regulating winding of the tapped transformer, in the constructional space of an interstice present in the transformer vessel. - a transformer vessel, in which at least one winding comprising a main winding and a regulating winding with winding taps, is arranged, - an on-load tap changer for uninterrupted switching over between the winding taps of the regulating winding, comprising • a selector for power-free selection of the respective winding tap which is to be switched over to and • a load changeover switch for the actual switching over from the connected to the new, preselected winding tap, • a selector for power-free selection of the respective winding tap which is to be switched over to and • a load changeover switch for the actual switching over from the connected to the new, preselected winding tap, - the selector and the load changeover switch are arranged spatially separately from one another, - the selector is arranged directly at the winding taps of the regulating winding of the tapped transformer, in the constructional space of an interstice present in the transformer vessel.
Light-emitting diode device, comprising - a carrier having at least one cavity or a plurality of cavities (51, 52, 53), - a light-emitting diode chip, which is arranged in a manner at least partly recessed in the at least one cavity or which is arranged on the carrier, - an ESD protection element, which is formed by a partial region of the carrier, characterized in that the light-emitting diode device comprises an electrical component and a further electrical component on the carrier, which components are arranged in a manner completely recessed in one or in a plurality of cavities (52, 53), wherein one of the electrical components (41, 42) is embodied as an NTC thermistor component and the other one of the electrical components (41, 42) is embodied as a PTC thermistor component and wherein the light-emitting diode chip is optically separated from the electrical component and from the further electrical component. - a carrier having at least one cavity or a plurality of cavities (51, 52, 53), - a light-emitting diode chip, which is arranged in a manner at least partly recessed in the at least one cavity or which is arranged on the carrier, - an ESD protection element, which is formed by a partial region of the carrier,
An apparatus for testing a cushioning component (12B, 12C, 12D, 12E, 12F, 12G, 12), the apparatus comprising: a jig (26A, 26) with a three-dimensional anatomical shape; a base (15A, 15, 16) configured to support the cushioning component (12B, 12C, 12D, 12E, 12F, 12G, 12); an actuator operatively connected to at least one of the jig (26A, 26) and the base (15A, 15, 16), and activatable to move said at least one of the jig (26A, 26) and the base (15A, 15, 16) toward and away from the other of the jig (26A, 26) and the base (15A, 15, 16) to repeatedly contact the cushioning component (12B, 12C, 12D, 12E, 12F, 12G, 12) and the jig (26A, 26) with one another when the cushioning component (12B, 12C, 12D, 12E, 12F, 12G, 12) is supported on the base (15A, 15, 16); an electronic controller operatively connected to the actuator; wherein the electronic controller has a processor that executes a stored algorithm; wherein the stored algorithm is a first reliability test having at least one test condition substantially equivalent to an expected in-use condition of the cushioning component (12B, 12C, 12D, 12E, 12F, 12G, 12); and wherein the electronic controller activates the actuator to move said at least one of the jig (26A, 26) and the base (15A, 15, 16) according to the stored algorithm; wherein the base (15A, 15, 16) includes a pivotable base plate; wherein the pivotable base plate has a support surface on which the cushioning component (12B, 12C, 12D, 12E, 12F, 12G, 12) is supportable; wherein the pivotable base plate pivots from a first position (43, 45) to a second position (43, 45) upon compression of the cushioning component (12B, 12C, 12D, 12E, 12F, 12G, 12) by the jig (26A, 26); and wherein an angle (95, 96) of application of jig (26A, 26) relative to a support surface of the base plate on which the cushioning component (12B, 12C, 12D, 12E, 12F, 12G, 12) is supported is different when the base plate is in the first position (43, 45) than when the base plate is in the second position (43, 45), such that a multi-axial deformation of the cushioning component (12B, 12C, 12D, 12E, 12F, 12G, 12) occurs, with shear forces, similar to in-use conditions.
A polymer composition comprising: (i) A silane-functionalized polymer, (ii) A polyfunctional alcohol wherein the polyfunctional alcohol is α,αα',α'-tetramethyl-1,3-benzenediethanol, and, (iii) A blocked, strong acid. (i) A silane-functionalized polymer, (ii) A polyfunctional alcohol wherein the polyfunctional alcohol is α,αα',α'-tetramethyl-1,3-benzenediethanol, and, (iii) A blocked, strong acid.
A passivating agent for metallic surfaces of workpieces or casting molds, comprising an aqueous phosphate solution with metal ions, characterized in that the passivating agent includes a gelatin, wherein a redox potential of the gelatin is set so that a gold number of the gelatin is smaller than 50 μmol Au/g of gelatin.
A device for the presentation of goods, comprising at least one mount intended for the direct suspension of articles or for holding secondary mounts (80, 81, 82), and at least one vertical support, which has a grid of slots of height (a), each having an upper edge and a lower edge, wherein at least one bracket (50, 60) of the mount (5, 6) can be mounted in the slots, wherein a) the grid of slots is arranged in a mirror-symmetrical manner in the vertical support in two parallel vertical lines, wherein each line of the grid of slots is delimited by an inner web; and b) the mount is provided with a bracket, which occupies slots of both lines of said vertical support in the inserted state; or c) the mount has two brackets, which each only occupy one line of slots of two adjacent vertical supports in the inserted state, characterised in that d) there is a separate inner web to delimit each line of slots in the vertical support; and e) the two inner webs enclose a cavity which is delimited by a base on the rear side. a) the grid of slots is arranged in a mirror-symmetrical manner in the vertical support in two parallel vertical lines, wherein each line of the grid of slots is delimited by an inner web; and b) the mount is provided with a bracket, which occupies slots of both lines of said vertical support in the inserted state; or c) the mount has two brackets, which each only occupy one line of slots of two adjacent vertical supports in the inserted state, characterised in that d) there is a separate inner web to delimit each line of slots in the vertical support; and e) the two inner webs enclose a cavity which is delimited by a base on the rear side.
A light emitting unit (10; 20; 30), comprising: a light emitting element (15a, 15b, 15c); a plurality of lead frames (11, 12a, 12b, 12c) to which said light emitting element is electrically connected, each lead frame (11, 12a, 12b, 12c) having a first terminal with a distal end for insertion into a circuit board; and a package in which said lead frames are inserted so that at least the first terminal of each lead frame protrudes from a bottom side face of the package, and on which a light emitting window is arranged through which light from the light emitting element is emitted, the light emitting unit (10; 20; 30) being of a type configured to emit light from the light emitting window in a direction which is substantially parallel to the plane of the circuit board into which the distal ends of the first terminals are to be inserted; wherein: at least the distal end of each first terminal is inclined with respect to a side of the light emitting window; characterised in that at least the distal end of each first terminal is also inclined with respect to the said bottom side face of the package from which the first terminals protrude. a light emitting element (15a, 15b, 15c); a plurality of lead frames (11, 12a, 12b, 12c) to which said light emitting element is electrically connected, each lead frame (11, 12a, 12b, 12c) having a first terminal with a distal end for insertion into a circuit board; and a package in which said lead frames are inserted so that at least the first terminal of each lead frame protrudes from a bottom side face of the package, and on which a light emitting window is arranged through which light from the light emitting element is emitted, the light emitting unit (10; 20; 30) being of a type configured to emit light from the light emitting window in a direction which is substantially parallel to the plane of the circuit board into which the distal ends of the first terminals are to be inserted; wherein: at least the distal end of each first terminal is inclined with respect to a side of the light emitting window; characterised in that at least the distal end of each first terminal is also inclined with respect to the said bottom side face of the package from which the first terminals protrude. at least the distal end of each first terminal is inclined with respect to a side of the light emitting window; characterised in that at least the distal end of each first terminal is also inclined with respect to the said bottom side face of the package from which the first terminals protrude.
Elevator safety device with a trigger which has an actuating element preloaded by means of at least one main spring and an electromagnetic actuator which holds the actuating element in its standby position by means of the electromagnetically generated force against the tension of the main spring, while the actuating element is brought into its triggering position by the main spring as soon as the electromagnetically generated force of the actuator drops, wherein the electromagnetic actuator acts on the actuating element via a converter, wherein the converter is designed in such a way that the force the actuator has to apply electromagnetically to hold the actuating element in its standby position is less than the force generated by the tension of the main spring, characterized in that the converter is formed by a blocking device or blocking rod coupled directly to the actuator in combination with a retaining element and a retaining tube and, against the effect of an auxiliary spring, the actuator holds the blocking element or the blocking rod in a position which forces a positive engagement between the at least one radially movable retaining element and the actuating element, wherein, when the actuator is not energized or not sufficiently energized, the auxiliary spring moves the blocking element into a position in which the positive engagement between the at least one retaining element and the actuating element can be cancelled by the force of the main spring.
In a computing environment, a system comprising a granular partial recall mechanism, wherein the system is configured, via the granular partial recall mechanism, to maintain information in association with an at least partially deduplicated file, which information tracks which range or ranges of file data of the at least partially deduplicated file are dirty relative to clean ranges because of data writes, the clean ranges corresponding to clean data in a chunk store, wherein the system is configured to track the dirty range or ranges at a granularity that is independent of file-system range tracking granularity and more fine-grained than the file-system range tracking granularity, wherein the system is configured, via the granular partial recall mechanism, to maintain the information in association with the at least partially deduplicated file in a plurality of hierarchically arranged bitmap data structures, wherein the plurality of hierarchically arranged bitmap data structures comprises a main recall bitmap tracking the actual dirty ranges and one or more recall bitmap index tables tracking aggregated dirtied ranges at a larger granularity; wherein the one or more recall bitmap index tables tracking aggregated dirtied ranges at a larger granularity comprises a root recall bitmap index table tracking aggregated dirtied ranges at the largest used granularity; wherein the main recall bitmap is stored in an external file while the root recall bitmap index table is stored in the reparse point of the at least partially deduplicated file.
Composition based on oak ( Castanopsis cuspidata and/or Quercus acuta) wood bark extracts comprising, by way of active ingredient, Nekka-Rich for use for the preventive and/or curative treatment of intestinal diseases caused by enterotoxigenic Escherichia coli (ETEC) in humans or in mammalian animals.