A compound of Formula IVA: or a salt thereof, wherein: R Ia is a moiety of the formula: (a) NH 2 -SO 2 -; (b) NR' 2 -SO 2 NR"-, wherein R' is independently for each occurrence: (i) -H; (ii) linear-, branched-, or cyclic-alkyl of up to 6 carbon atoms; or (iii) one of R' is -H and the other is t-BOC; and R" is: (a) -H; or (b) linear-, branched-, or cyclic-alkyl of up to 6 carbon atoms; or (iv) one of R' is - H and the other R' together with R" and the -N-SO 2 -N- moiety to which they a re attached form a heterocycle of up to 6 ring atoms; R Ib has the formula: -CH 2 -X-, wherein X is -O-, -S-, CH 2 -; R Id and R Ie are independently for each occurrence -H or linear-, branched-, or cyclic-alkyl of up to 6 carbon atoms; or R Id and R Ie together with the cyclopropyl moiety to which they are attached from a spirocycl of up to 8 carbon atoms; R Ic is: (a) a heteroaryl of the formula: wherein: n = 0, 1, or 2; one of R IIa or R IIb is a bond to the cyclopropyl core of Formula IVA and the other is - H or -R IIc, wherein, R IIc is: (i) linear-, branched-, or cyclic- alkoxy of up to 6 carbon, which may optionally be substituted with one or more halogen; (ii) linear-, branched-, or cyclic-alkyl of up to 6 carbon atoms, which may optionally be substituted with halogen or linear-, branched-, or cyclic- alkoxy of up to 6 carbon atoms; or (b) aryl of the formula wherein: n = 1 or 2; R IIIa is: (i) halogen; (ii) linear-, branched-, or cyclic-alkoxy of up to 6 carbon atoms which may optionally be substituted with one or more halogen; or linear-, branched-, or cyclic alkoxy of up to 6 carbon atoms; (iii) linear-, branched-, or cyclic-alkyl of up to 6 carbon atoms which may optionally be substituted with one or more: halogen; or linear-, branched-, or cyclic alkoxy of up to 6 carbon atoms, R Ia is a moiety of the formula: (a) NH 2 -SO 2 -; (b) NR' 2 -SO 2 NR"-, wherein R' is independently for each occurrence: (i) -H; (ii) linear-, branched-, or cyclic-alkyl of up to 6 carbon atoms; or (iii) one of R' is -H and the other is t-BOC; and R" is: (a) -H; or (b) linear-, branched-, or cyclic-alkyl of up to 6 carbon atoms; or (iv) one of R' is - H and the other R' together with R" and the -N-SO 2 -N- moiety to which they a re attached form a heterocycle of up to 6 ring atoms; R Ib has the formula: -CH 2 -X-, wherein X is -O-, -S-, CH 2 -; R Id and R Ie are independently for each occurrence -H or linear-, branched-, or cyclic-alkyl of up to 6 carbon atoms; or R Id and R Ie together with the cyclopropyl moiety to which they are attached from a spirocycl of up to 8 carbon atoms; R Ic is: (a) a heteroaryl of the formula: wherein: n = 0, 1, or 2; one of R IIa or R IIb is a bond to the cyclopropyl core of Formula IVA and the other is - H or -R IIc, wherein, R IIc is: (i) linear-, branched-, or cyclic- alkoxy of up to 6 carbon, which may optionally be substituted with one or more halogen; (ii) linear-, branched-, or cyclic-alkyl of up to 6 carbon atoms, which may optionally be substituted with halogen or linear-, branched-, or cyclic- alkoxy of up to 6 carbon atoms; or (b) aryl of the formula wherein: n = 1 or 2; R IIIa is: (i) halogen; (ii) linear-, branched-, or cyclic-alkoxy of up to 6 carbon atoms which may optionally be substituted with one or more halogen; or linear-, branched-, or cyclic alkoxy of up to 6 carbon atoms; (iii) linear-, branched-, or cyclic-alkyl of up to 6 carbon atoms which may optionally be substituted with one or more: halogen; or linear-, branched-, or cyclic alkoxy of up to 6 carbon atoms, (a) a heteroaryl of the formula: wherein: n = 0, 1, or 2; one of R IIa or R IIb is a bond to the cyclopropyl core of Formula IVA and the other is - H or -R IIc, wherein, R IIc is: (i) linear-, branched-, or cyclic- alkoxy of up to 6 carbon, which may optionally be substituted with one or more halogen; (ii) linear-, branched-, or cyclic-alkyl of up to 6 carbon atoms, which may optionally be substituted with halogen or linear-, branched-, or cyclic- alkoxy of up to 6 carbon atoms; or n = 0, 1, or 2; one of R IIa or R IIb is a bond to the cyclopropyl core of Formula IVA and the other is - H or -R IIc, wherein, R IIc is: (i) linear-, branched-, or cyclic- alkoxy of up to 6 carbon, which may optionally be substituted with one or more halogen; (ii) linear-, branched-, or cyclic-alkyl of up to 6 carbon atoms, which may optionally be substituted with halogen or linear-, branched-, or cyclic- alkoxy of up to 6 carbon atoms; or (b) aryl of the formula wherein: n = 1 or 2; R IIIa is: (i) halogen; (ii) linear-, branched-, or cyclic-alkoxy of up to 6 carbon atoms which may optionally be substituted with one or more halogen; or linear-, branched-, or cyclic alkoxy of up to 6 carbon atoms; (iii) linear-, branched-, or cyclic-alkyl of up to 6 carbon atoms which may optionally be substituted with one or more: halogen; or linear-, branched-, or cyclic alkoxy of up to 6 carbon atoms, n = 1 or 2; R IIIa is: (i) halogen; (ii) linear-, branched-, or cyclic-alkoxy of up to 6 carbon atoms which may optionally be substituted with one or more halogen; or linear-, branched-, or cyclic alkoxy of up to 6 carbon atoms; (iii) linear-, branched-, or cyclic-alkyl of up to 6 carbon atoms which may optionally be substituted with one or more: halogen; or linear-, branched-, or cyclic alkoxy of up to 6 carbon atoms,