Method for measurement in high-throughput screening with high time-resolution, comprising the steps of: a. providing i. a microtitre plate having a transparent base with a multiplicity of assay wells, ii. a dispensing system arranged above the microtitre plate for the simultaneous addition of liquid into multiple assay wells, the dispensing system comprising a dispensing device and the dispensing device comprising a housing having at least one pressure chamber, having a supply opening for the supply of liquid into the pressure chamber and having a multiplicity of conduits between the pressure chamber and an external side of the housing, there being situated in each of the conduits a tube, the first end of which protrudes into the pressure chamber and the second end of which protrudes out of the housing on the external side; iii. an illumination system beneath the microtitre plate that is suitable for illuminating the multiple assay wells simultaneously through the transparent base; and iv. a detection system that is suitable for detecting electromagnetic radiation from the multiple or all the assay wells simultaneously through the transparent base. b. adding 0.3 - 300 μl of liquid per assay well from the dispensing system into the multiple assay wells simultaneously within 5-200 ms at a pressure within the range from 50 kPa (0.5 bar) to 200 kPa (2 bar). c. illuminating the multiple assay wells simultaneously through the transparent base using the illumination system with the start of illumination before or from the time point of the start of the addition; d. detecting the electromagnetic radiation from the multiple or all the assay wells simultaneously at a time interval of 1 - 1000 ms between the individual measurement points. a. providing i. a microtitre plate having a transparent base with a multiplicity of assay wells, ii. a dispensing system arranged above the microtitre plate for the simultaneous addition of liquid into multiple assay wells, the dispensing system comprising a dispensing device and the dispensing device comprising a housing having at least one pressure chamber, having a supply opening for the supply of liquid into the pressure chamber and having a multiplicity of conduits between the pressure chamber and an external side of the housing, there being situated in each of the conduits a tube, the first end of which protrudes into the pressure chamber and the second end of which protrudes out of the housing on the external side; iii. an illumination system beneath the microtitre plate that is suitable for illuminating the multiple assay wells simultaneously through the transparent base; and iv. a detection system that is suitable for detecting electromagnetic radiation from the multiple or all the assay wells simultaneously through the transparent base. i. a microtitre plate having a transparent base with a multiplicity of assay wells, ii. a dispensing system arranged above the microtitre plate for the simultaneous addition of liquid into multiple assay wells, the dispensing system comprising a dispensing device and the dispensing device comprising a housing having at least one pressure chamber, having a supply opening for the supply of liquid into the pressure chamber and having a multiplicity of conduits between the pressure chamber and an external side of the housing, there being situated in each of the conduits a tube, the first end of which protrudes into the pressure chamber and the second end of which protrudes out of the housing on the external side; iii. an illumination system beneath the microtitre plate that is suitable for illuminating the multiple assay wells simultaneously through the transparent base; and iv. a detection system that is suitable for detecting electromagnetic radiation from the multiple or all the assay wells simultaneously through the transparent base. b. adding 0.3 - 300 μl of liquid per assay well from the dispensing system into the multiple assay wells simultaneously within 5-200 ms at a pressure within the range from 50 kPa (0.5 bar) to 200 kPa (2 bar). c. illuminating the multiple assay wells simultaneously through the transparent base using the illumination system with the start of illumination before or from the time point of the start of the addition; d. detecting the electromagnetic radiation from the multiple or all the assay wells simultaneously at a time interval of 1 - 1000 ms between the individual measurement points.