mhurhangee/ep-ind-claims huggingface dataset:
A pneumatic tyre comprising: a tread portion comprising a shoulder land portion having a tread edge (Te), wherein the tread edge (Te) is an axial outermost edge of a ground contact surface of the tyre which occurs under a normal state of the tyre loaded with a standard tyre load when a camber angle of the tyre is zero, the shoulder land portion being provided with shoulder lateral grooves extending inwardly in a tyre axial direction from the tread edge (Te) so as to define shoulder block elements therebetween, and at least one protrusion protruding from an outer surface in the tyre axial direction of the respective shoulder land portion, wherein the at least one protrusion comprising first portions provided on the respective shoulder block elements and extending in a tyre radial direction, and a second portion located inwardly in the tyre radial direction of one of the shoulder lateral grooves and extending in a tyre circumferential direction to connect inner portions of at least two first portions, characterized in that in a cross-sectional view in parallel with the tyre circumferential direction, the first portions each protrude in a tapered manner such that side surfaces thereof are inclined at an angle ( α 1) of equal to or less than 45 degrees with respect to a normal line (n) of the outer surface of the shoulder land portion. a tread portion comprising a shoulder land portion having a tread edge (Te), wherein the tread edge (Te) is an axial outermost edge of a ground contact surface of the tyre which occurs under a normal state of the tyre loaded with a standard tyre load when a camber angle of the tyre is zero, the shoulder land portion being provided with shoulder lateral grooves extending inwardly in a tyre axial direction from the tread edge (Te) so as to define shoulder block elements therebetween, and at least one protrusion protruding from an outer surface in the tyre axial direction of the respective shoulder land portion, wherein the at least one protrusion comprising first portions provided on the respective shoulder block elements and extending in a tyre radial direction, and a second portion located inwardly in the tyre radial direction of one of the shoulder lateral grooves and extending in a tyre circumferential direction to connect inner portions of at least two first portions, characterized in that in a cross-sectional view in parallel with the tyre circumferential direction, the first portions each protrude in a tapered manner such that side surfaces thereof are inclined at an angle ( α 1) of equal to or less than 45 degrees with respect to a normal line (n) of the outer surface of the shoulder land portion.
A compound for use in a method of protecting a mammal from the effects of one or more treatments or conditions that trigger apoptosis, the method comprising administering to said mammal a pharmaceutically effective amount of said compound, wherein said compound is of the formula: wherein: R 1 represents H or -CO-R 4, R 2, R 3, and R 4 independently are H or optionally substituted C 6 -C 20 aliphatic; X is a peptide; Z is S or CH 2; and the peptide consists of no more than 40 amino acids and comprises a sequence selected from SEQ ID NOs: 8, 16, 17, 18, 20, 21, and 24. R 1 represents H or -CO-R 4, R 2, R 3, and R 4 independently are H or optionally substituted C 6 -C 20 aliphatic; X is a peptide; Z is S or CH 2; and the peptide consists of no more than 40 amino acids and comprises a sequence selected from SEQ ID NOs: 8, 16, 17, 18, 20, 21, and 24.
A polypeptide composition comprising: a) a first peptide; b) a second peptide; and c) a linker consisting of one to four sequential repeats of the amino acid sequence of SEQ ID NO. 1, and optionally the amino acid sequence glycine alanine proline at the C-terminus, wherein the linker is disposed between said first peptide and said second peptide. a) a first peptide; b) a second peptide; and c) a linker consisting of one to four sequential repeats of the amino acid sequence of SEQ ID NO. 1, and optionally the amino acid sequence glycine alanine proline at the C-terminus, wherein the linker is disposed between said first peptide and said second peptide.
A stereolithography apparatus material provision device for print material to be cured, in particular a photopolymer, wherein the material provision device receives a material cartridge which in turn receives the print material and surrounds it on all sides, wherein the material cartridge comprises an outlet valve unit via which the print material may be output and which is received at least partially in the material provision device and which is supported at least partially thereon or therein or sealed against it, characterized in that the outlet valve unit comprises a valve which is opened and closed depending on the swiveling position of the material provision device and stereolithography apparatus.
A process for removing at least one degradation acid from a catalyst solution comprising at least one phosphorus-containing hydroformylation ligand, said process comprising contacting at least a portion of said catalyst solution with at least one supported epoxy compound at conditions effective to remove at least a portion of said at least one degradation acid from said catalyst solution.
A selective catalytic reduction system for treating exhaust gas from a diesel engine, the system comprising: a frame; a SCR catalyst contained within a SCR canister; a hydrolysis catalyst contained within a hydrolysis catalyst canister upstream of the SCR catalyst; and an ammonia oxidation catalyst contained within an ammonia oxidation canister; wherein each of the SCR, hydrolysis catalyst and ammonia oxidation canisters (48,40,56) is removably attached to the frame. a frame; a SCR catalyst contained within a SCR canister; a hydrolysis catalyst contained within a hydrolysis catalyst canister upstream of the SCR catalyst; and an ammonia oxidation catalyst contained within an ammonia oxidation canister; wherein each of the SCR, hydrolysis catalyst and ammonia oxidation canisters (48,40,56) is removably attached to the frame.
A manufacturing method for a terminal (10; 20) including a board connecting portion (12; 22) to be connected to a circular through hole formed to penetrate through a board, comprising: a wire drawing step of manufacturing a wire material having a polygonal cross-section with obtuse interior angles by drawing the wire material through an opening of a wire drawing die, the opening having a polygonal shape with obtuse inner angles; a surface processing step of at least partly applying a surface processing to the wire material; and a cutting step of cutting the wire material having the surface processing applied thereto to a specified length to form the terminal (10; 20); wherein the surface processing step comprises applying tin plating to the wire material; wherein the wire material is shaped to substantially taper a leading end part of the board connecting portion (12; 22; 32; 42), characterized in that tin is peeled off when the leading end part is shaped. a wire drawing step of manufacturing a wire material having a polygonal cross-section with obtuse interior angles by drawing the wire material through an opening of a wire drawing die, the opening having a polygonal shape with obtuse inner angles; a surface processing step of at least partly applying a surface processing to the wire material; and a cutting step of cutting the wire material having the surface processing applied thereto to a specified length to form the terminal (10; 20); wherein the surface processing step comprises applying tin plating to the wire material; wherein the wire material is shaped to substantially taper a leading end part of the board connecting portion (12; 22; 32; 42), characterized in that tin is peeled off when the leading end part is shaped.
A method of amplifying RNA from one or more cells, comprising the steps of: exposing RNA from the one or more cells to a first plurality of primers and to at least one reverse transcriptase to produce a reaction mixture; subjecting said reaction mixture to conditions in that allow annealing of the primers to the RNA and first-strand cDNA synthesis to produce extended DNA strands; digesting unannealed primers; inactivating enzymes in the reaction mixture; digesting RNA in the reaction mixture; tailing the 3' ends of the extended DNA strands; generating second-strand cDNA synthesis using a second plurality of primers and at least one DNA polymerase under suitable conditions to produce double-stranded full amplicons, wherein the primers in the first plurality, second plurality, or both comprise the following formula: XnYmZp, wherein n is greater than 2 and X is 40%-60% G-rich or 40%-60% C-rich, wherein Y is any nucleotide and m is 5-8 nucleotides and wherein Z is a T and a G when X is G-rich or C when X is C-rich, wherein p is 2-20 nucleotides. exposing RNA from the one or more cells to a first plurality of primers and to at least one reverse transcriptase to produce a reaction mixture; subjecting said reaction mixture to conditions in that allow annealing of the primers to the RNA and first-strand cDNA synthesis to produce extended DNA strands; digesting unannealed primers; inactivating enzymes in the reaction mixture; digesting RNA in the reaction mixture; tailing the 3' ends of the extended DNA strands; generating second-strand cDNA synthesis using a second plurality of primers and at least one DNA polymerase under suitable conditions to produce double-stranded full amplicons, wherein the primers in the first plurality, second plurality, or both comprise the following formula: XnYmZp, wherein n is greater than 2 and X is 40%-60% G-rich or 40%-60% C-rich, wherein Y is any nucleotide and m is 5-8 nucleotides and wherein Z is a T and a G when X is G-rich or C when X is C-rich, wherein p is 2-20 nucleotides.
Mifepristone and octreotide for use in the treatment of Cushing's syndrome in a patient having an adrenocorticotropic hormone (ACTH)-secreting pancreatic neuroendocrine tumor, wherein the octreotide is administered first followed by a second administration of mifepristone.
A work module for removable mounting to a jaw assembly of a demolition tool, the work module comprising: a base; at least one tooth extending from the base; a mounting element extending from the base in a direction opposite to the at least one tooth, the mounting element being couplable to an at least one seating portion disposed on a second jaw of the jaw assembly characterised in that a positioning element is interposed between the base and the mounting element, the positioning element being provided within the perimeter of the base. a base; at least one tooth extending from the base; a mounting element extending from the base in a direction opposite to the at least one tooth, the mounting element being couplable to an at least one seating portion disposed on a second jaw of the jaw assembly characterised in that a positioning element is interposed between the base and the mounting element, the positioning element being provided within the perimeter of the base.
Press comprising: - at least one punching unit arranged for receiving a sheet that advances in an indexed manner and for shearing the sheet in dwell phases thereof, separating into several phases a plurality of disks from the sheet according to a regular arrangement and leaving a continuous conveyable reject grid; - at least one movable conveyor arranged for supplying a sheet to be sheared through said punching unit; - gripping means spaced apart from one another along said conveyor and movable together therewith for maintaining a sheet gripped; - first driving means for opening and closing said punching unit; - second driving means for moving said movable conveyor in an indexed manner; wherein said gripping means is arranged for maintaining a sheet gripped during shearing and for releasing it after shearing as a reject grid, and said second driving means is distinct from said first driving means; characterized in that said conveyor is a closed-loop conveyor and said gripping means comprises two or more gripping members arranged on said closed-loop conveyor and spaced apart from one another so as to cyclically have a sheet-changing step in the punching unit wherein there is simultaneously at least one of said gripping members that grips a sheet arranged upstream of said punching unit and at least another one of said gripping members that grips a reject grid arranged downstream of said punching unit. - at least one punching unit arranged for receiving a sheet that advances in an indexed manner and for shearing the sheet in dwell phases thereof, separating into several phases a plurality of disks from the sheet according to a regular arrangement and leaving a continuous conveyable reject grid; - at least one movable conveyor arranged for supplying a sheet to be sheared through said punching unit; - gripping means spaced apart from one another along said conveyor and movable together therewith for maintaining a sheet gripped; - first driving means for opening and closing said punching unit; - second driving means for moving said movable conveyor in an indexed manner;
Ultrasound imaging device comprising an assembly of ultrasound transducers distributed in a plurality of sub-assemblies of P transducers each, the device comprising, for each sub-assembly: - K transceiver circuits (123 k); and - a configurable routing circuit coupling the P transducers of the sub-assembly to the K transceiver circuits (123 k), wherein P and K are integers greater than or equal to 2, with K smaller than P, and wherein each sub-assembly comprises at least one transducer (103(b), 103(c)), called mobile transducer, capable of being, via the routing circuit, disconnected or connected to any one among a plurality of predefined transceiver circuits (123 k) among the K transceiver circuits (123 k) of the sub-assembly, the device being characterized in that each sub-assembly further comprises at least one transducer (103(a), 103(d)), called fixed transducer, capable of being, via the routing circuit of the sub-assembly, disconnected or connected to a single predefined transceiver circuit from among K transceiver circuits (123 k) of the sub-assembly. - K transceiver circuits (123 k); and - a configurable routing circuit coupling the P transducers of the sub-assembly to the K transceiver circuits (123 k), wherein P and K are integers greater than or equal to 2, with K smaller than P, and wherein each sub-assembly comprises at least one transducer (103(b), 103(c)), called mobile transducer, capable of being, via the routing circuit, disconnected or connected to any one among a plurality of predefined transceiver circuits (123 k) among the K transceiver circuits (123 k) of the sub-assembly, the device being characterized in that each sub-assembly further comprises at least one transducer (103(a), 103(d)), called fixed transducer, capable of being, via the routing circuit of the sub-assembly, disconnected or connected to a single predefined transceiver circuit from among K transceiver circuits (123 k) of the sub-assembly.
Mobile valve member that is designed to be arranged in the nozzle body of a fuel injector, the mobile member extending along a main axis between a top end and a bottom end that is provided with a mobile valve seat designed to cooperate with a static seat arranged on the inner face of the nozzle body about a circular line of the effective diameter, the mobile member being designed to slide between a closed position in which the two valve seats (46, 56) are in sealing contact about said circular line to prevent fuel injection, and an open position in which the two valve seats are separated from one another to enable said injection; characterized in that the mobile member includes: - a piston made up of a first male cylinder of effective diameter forming the top end of the mobile member and a second cylinder with a greater external diameter provided with an internal cylindrical bore of effective diameter extending axially in the second cylinder as far as a back, - a shutoff member made up of a cylindrical body comprising a male cylindrical shaft of effective diameter that fits slidingly with clearance in the internal bore of the piston, and a male pointed cylindrical member with a greater diameter than the effective diameter, the pointed cylindrical member extending as far as a pointed end including the mobile valve seat and forming the bottom end of the mobile member, such that the mobile valve member is hydraulically balanced and the length between the top end and the bottom end thereof is variable as a result of the sliding of the cylindrical shaft in the internal bore of the piston; the mobile valve member also including a first compressed spring between the piston and the shutoff member that permanently stresses the piston and the shutoff member to extend the mobile member. - a piston made up of a first male cylinder of effective diameter forming the top end of the mobile member and a second cylinder with a greater external diameter provided with an internal cylindrical bore of effective diameter extending axially in the second cylinder as far as a back, - a shutoff member made up of a cylindrical body comprising a male cylindrical shaft of effective diameter that fits slidingly with clearance in the internal bore of the piston, and a male pointed cylindrical member with a greater diameter than the effective diameter, the pointed cylindrical member extending as far as a pointed end including the mobile valve seat and forming the bottom end of the mobile member,
A method of producing human cells expressing markers characteristic of pancreatic endocrine cells comprising differentiating human cells expressing markers characteristic of pancreatic endoderm cells into human cells expressing markers characteristic of pancreatic endocrine cells by treatment with at least one medium supplemented with an ALK5 inhibitor, or both an ALK5 inhibitor and a thyroid hormone selected from triiodothyronine, thyroxine, GC-1, 3,5-diiodothyropropionic acid, KB-141, MB07344, T0681, and GC-24 and mixtures thereof, while culturing at the air-liquid interface.
Bearing arrangement for mounting a container processing carousel with respect to a base frame of a container processing apparatus in a beverage filling installation, comprising a bearing shaft which extends along a longitudinal axis, a bearing cup which is rotatable relative to the bearing shaft, an adjusted bearing assembly arranged between the bearing shaft and the bearing cup for mounting the bearing cup with respect to the bearing shaft, and an annular preload unit for applying a specified preload to the adjusted bearing assembly, characterized in that the annular preload unit for applying the preload to the adjusted bearing assembly comprises a plurality of spring packages which are distributed uniformly in a circumferential direction relative to the longitudinal axis.
A system, comprising: a cochlear implant comprising: an implantable stimulator unit, and an elongate stimulating assembly comprising a plurality of longitudinally spaced contacts configured to be inserted into a recipient's cochlea; and a processor, characterized in that the processor is configured to: during insertion of the stimulating assembly into the cochlea, perform one or more electrical measurements, and based on the one or more electrical measurements, set an angular insertion depth for the stimulating assembly. a cochlear implant comprising: an implantable stimulator unit, and an elongate stimulating assembly comprising a plurality of longitudinally spaced contacts configured to be inserted into a recipient's cochlea; and a processor, characterized in that the processor is configured to: during insertion of the stimulating assembly into the cochlea, perform one or more electrical measurements, and based on the one or more electrical measurements, set an angular insertion depth for the stimulating assembly. an implantable stimulator unit, and an elongate stimulating assembly comprising a plurality of longitudinally spaced contacts configured to be inserted into a recipient's cochlea; and a processor, characterized in that the processor is configured to: during insertion of the stimulating assembly into the cochlea, perform one or more electrical measurements, and based on the one or more electrical measurements, set an angular insertion depth for the stimulating assembly. during insertion of the stimulating assembly into the cochlea, perform one or more electrical measurements, and based on the one or more electrical measurements, set an angular insertion depth for the stimulating assembly.
Method for recontouring a gas turbine blade, wherein a device for recontouring a gas turbine blade, comprising - a holding device with at least one cutting tool, and - a guide device for guiding the cutting tool along a leading edge of the gas turbine blade, is used for recontouring, wherein - the cutting tool removes material from the gas turbine blade by means of a rotational movement about an axis of rotation, wherein - the axis of rotation forms an angle (α, β) together with a chord of the gas turbine blade in a profile section plane, which extends perpendicularly to a radial extent of the gas turbine blade, wherein the chord is the direct connection line between the leading edge and a trailing edge of the gas turbine blade in the profile section plane, wherein - the angle (α, β) is less than 45°, and - the cutting tool is formed of a radial milling cutter, a radial grinding wheel, a contour milling cutter or a contour grinding wheel. - a holding device with at least one cutting tool, and - a guide device for guiding the cutting tool along a leading edge of the gas turbine blade, - the cutting tool removes material from the gas turbine blade by means of a rotational movement about an axis of rotation, wherein - the axis of rotation forms an angle (α, β) together with a chord of the gas turbine blade in a profile section plane, which extends perpendicularly to a radial extent of the gas turbine blade, wherein the chord is the direct connection line between the leading edge and a trailing edge of the gas turbine blade in the profile section plane, wherein - the angle (α, β) is less than 45°, and - the cutting tool is formed of a radial milling cutter, a radial grinding wheel, a contour milling cutter or a contour grinding wheel.