mhurhangee/ep-ind-claims huggingface dataset:
Method for encapsulating an active ingredient in a liposome consisting of the following sequential steps: preparing an ethanolic phase by mixing hydrophobic molecules of phospholipids and a steroid with ethanol, preparing an aqueous phase with an active ingredient and a targeting agent in a buffer solution; obtaining the liposomes by injecting the ethanolic phase in the aqueous phase, at a temperature from around 50 °C to around 80 °C, wherein the ethanolic/aqueous phase volume ratio is between 1:1 and 3:2; removing the ethanol; removing the remaining free active ingredient in a suitable way, namely by tangencial flow filtration; optionally, the step of diluting of the liposomal dispersion 1 to 10-fold in further diluted aqueous phase; wherein the targeting agent is a peptide that is conjugated with a liposomal component or incorporated in the lipidic membrane; wherein the ethanol concentration, relative to initial aqueous volume, is between 40% and 60%. preparing an ethanolic phase by mixing hydrophobic molecules of phospholipids and a steroid with ethanol, preparing an aqueous phase with an active ingredient and a targeting agent in a buffer solution; obtaining the liposomes by injecting the ethanolic phase in the aqueous phase, at a temperature from around 50 °C to around 80 °C, wherein the ethanolic/aqueous phase volume ratio is between 1:1 and 3:2; removing the ethanol; removing the remaining free active ingredient in a suitable way, namely by tangencial flow filtration; optionally, the step of diluting of the liposomal dispersion 1 to 10-fold in further diluted aqueous phase; wherein the targeting agent is a peptide that is conjugated with a liposomal component or incorporated in the lipidic membrane; wherein the ethanol concentration, relative to initial aqueous volume, is between 40% and 60%.
A method for assembling a control arrangement of an exhaust-gas turbocharger, having the following method steps: a. inserting a bushing into a turbine housing recess; b. inserting a spindle into the bushing; c. placing a valve disk against a wastegate opening of the turbine housing; d. mounting an intermediate piece onto one end of the spindle; e. connecting, preferably welding, the intermediate piece to the end of the spindle; f. adjusting an angle between an outer lever and the spindle relative to the valve disk; g. fastening, preferably welding, the lever to the spindle; h. pulling on the lever in the closing direction of the valve disk to hold the disk firmly with sealing action against a valve seat; i. welding the valve disk to a spherical segment of the spindle in this state. a. inserting a bushing into a turbine housing recess; b. inserting a spindle into the bushing; c. placing a valve disk against a wastegate opening of the turbine housing; d. mounting an intermediate piece onto one end of the spindle; e. connecting, preferably welding, the intermediate piece to the end of the spindle; f. adjusting an angle between an outer lever and the spindle relative to the valve disk; g. fastening, preferably welding, the lever to the spindle; h. pulling on the lever in the closing direction of the valve disk to hold the disk firmly with sealing action against a valve seat; i. welding the valve disk to a spherical segment of the spindle in this state.
A device for measuring the mass flow of conveyed materials in a pneumatic conveyor line, comprising: - a feed conveyor line; - a discharge conveyor line; - a pipe bend, whose ends are connected to the feed conveyor line and the discharge conveyor line via flexible coupling sleeves (2, 3); - means for measuring the reaction force applied to the pipe bend as a result of the bulk material mass flow; - an arithmetic unit for calculating the instantaneous mass flow via the measured reaction force; - means for detecting the effect of pressure fluctuations in the conveyor line; and - means for the floating suspension of the pipe bend are present, which have a freely rotatable bearing of the pipe bend, the latter having a device-fixed pivot bearing point (60, 61), which cooperates with an axis, which carries the pipe bend in an oscillating manner via a hub and spokes. - a feed conveyor line; - a discharge conveyor line; - a pipe bend, whose ends are connected to the feed conveyor line and the discharge conveyor line via flexible coupling sleeves (2, 3); - means for measuring the reaction force applied to the pipe bend as a result of the bulk material mass flow; - an arithmetic unit for calculating the instantaneous mass flow via the measured reaction force; - means for detecting the effect of pressure fluctuations in the conveyor line; and - means for the floating suspension of the pipe bend are present, which have a freely rotatable bearing of the pipe bend, the latter having a device-fixed pivot bearing point (60, 61), which cooperates with an axis, which carries the pipe bend in an oscillating manner via a hub and spokes.
An atomizer for an electronic cigarette, comprising: a substrate, a heating device, and a cover member, wherein the substrate is provided with a mounting space, one end of the heating device is inserted into the mounting space and partially extends to the outside through the substrate to form a controlling member, and the other end is exposed to the outer surface of the substrate, wherein the atomizer is configured such that, when the controlling member is pressed into the substrate by an external pressing force, the heating device is capable of being pushed to move toward the outside of the substrate along the mounting space and partially extending out of the substrate, and the cover member is detachably mounted to the substrate and is configured for covering the controlling member; characterized in that: the substrate is further convexly provided with a supporting member at both sides adjacent to the controlling member and an outer peripheral surface of the supporting member is closely fitted to the inner wall of the cover member so that the cover member is fixedly mounted to the substrate; and a supporting space is formed between the two supporting members and a surface of an extending end of the supporting member is flush with or higher than a surface of the controlling member extending beyond the substrate. a substrate, a heating device, and a cover member, wherein the substrate is provided with a mounting space, one end of the heating device is inserted into the mounting space and partially extends to the outside through the substrate to form a controlling member, and the other end is exposed to the outer surface of the substrate, wherein the atomizer is configured such that, when the controlling member is pressed into the substrate by an external pressing force, the heating device is capable of being pushed to move toward the outside of the substrate along the mounting space and partially extending out of the substrate, and the cover member is detachably mounted to the substrate and is configured for covering the controlling member; characterized in that: the substrate is further convexly provided with a supporting member at both sides adjacent to the controlling member and an outer peripheral surface of the supporting member is closely fitted to the inner wall of the cover member so that the cover member is fixedly mounted to the substrate; and a supporting space is formed between the two supporting members and a surface of an extending end of the supporting member is flush with or higher than a surface of the controlling member extending beyond the substrate. the substrate is further convexly provided with a supporting member at both sides adjacent to the controlling member and an outer peripheral surface of the supporting member is closely fitted to the inner wall of the cover member so that the cover member is fixedly mounted to the substrate; and a supporting space is formed between the two supporting members and a surface of an extending end of the supporting member is flush with or higher than a surface of the controlling member extending beyond the substrate.
A freezer for a product, comprising: - a housing having a space therein, and an inlet and an outlet in communication with the space; - a conveyor having a first side for conveying the product through the space, and a second side opposite to the first side; - an agitating apparatus disposed proximate the conveyor for contacting the conveyor at select intervals to agitate the conveyor and displace the product at the first side; characterized by - a first longitudinal member disposed proximate the first side of the conveyor and having at least one hole extending therethrough; - at least one circulation device disposed in the space proximate the first longitudinal member for directing a cryogenic substance through the at least one hole onto the product; and - a second longitudinal member disposed proximate the second side of the conveyor and having at least another one hole extending therethrough. - a housing having a space therein, and an inlet and an outlet in communication with the space; - a conveyor having a first side for conveying the product through the space, and a second side opposite to the first side; - an agitating apparatus disposed proximate the conveyor for contacting the conveyor at select intervals to agitate the conveyor and displace the product at the first side; characterized by - a first longitudinal member disposed proximate the first side of the conveyor and having at least one hole extending therethrough; - at least one circulation device disposed in the space proximate the first longitudinal member for directing a cryogenic substance through the at least one hole onto the product; and - a second longitudinal member disposed proximate the second side of the conveyor and having at least another one hole extending therethrough.
Medical formulation comprising, as daily dose: - 1 to 500 mg bark extract of cinnamomum zeylanicum; - 1 to 300 mg fibre extract of Pinus pinaster; - 1 to 300 mg bark extract of a plant belonging to the Saccharum genus; - 1 to 1500 mg extract of Monascus purpureus; - 1 to 300 mg leaf extract of Taraxacum officinale; - 1 to 300 mg leaf extract of Camellia sinensis; - 1 to 300 mg vitamin B3; - 1 to 300 mg alpha tocopherol 50%; - 1 to 400 mg coenzyme Q 10; - 1 to 500 mg fish oil comprising 18 to 22 wt% of the fish oil eicosapentaenoic acid and 10 to 15 wt % of the fish oil docosahexanoic acid; - 0.1 to 150 mg beta-glucan; - 0.1 to 200 mg cholecalciferol; and - 1 to 100 mg zinc bisglycinate, wherein the medical formulation is able to lower LDL cholesterol blood levels, improve total cholesterol blood levels, increase HDL blood levels, lower triglyceride blood levels, and/or lower the systolic blood pressure. - 1 to 500 mg bark extract of cinnamomum zeylanicum; - 1 to 300 mg fibre extract of Pinus pinaster; - 1 to 300 mg bark extract of a plant belonging to the Saccharum genus; - 1 to 1500 mg extract of Monascus purpureus; - 1 to 300 mg leaf extract of Taraxacum officinale; - 1 to 300 mg leaf extract of Camellia sinensis; - 1 to 300 mg vitamin B3; - 1 to 300 mg alpha tocopherol 50%; - 1 to 400 mg coenzyme Q 10; - 1 to 500 mg fish oil comprising 18 to 22 wt% of the fish oil eicosapentaenoic acid and 10 to 15 wt % of the fish oil docosahexanoic acid; - 0.1 to 150 mg beta-glucan; - 0.1 to 200 mg cholecalciferol; and - 1 to 100 mg zinc bisglycinate,
A polymer composition comprising: at least two polyethylene polymers, and a functional filler comprising inorganic particulate and a surface treatment agent on a surface of the inorganic particulate, wherein the functional filler is present in an amount ranging from 1% to 70 % by weight of the polymer composition; wherein the at least two polyethylene polymers are coupled by the functional filler, wherein a first of the at least two polyethylene polymers comprises HDPE, wherein the second of the at least two polyethylene polymers comprises HDPE wherein the HDPE of the second polyethylene polymer is different than the HDPE of the first polyethylene polymer, the weight ratio of the HDPE of the first polyethylene polymer to the HDPE of the second polyethylene polymer is from 0.5 to 3:1, and wherein the total amount of HDPE present in the polymer composition is from 50 % by weight to 90 % by weight of the polymer composition. at least two polyethylene polymers, and a functional filler comprising inorganic particulate and a surface treatment agent on a surface of the inorganic particulate, wherein the functional filler is present in an amount ranging from 1% to 70 % by weight of the polymer composition; wherein the at least two polyethylene polymers are coupled by the functional filler, wherein a first of the at least two polyethylene polymers comprises HDPE, wherein the second of the at least two polyethylene polymers comprises HDPE wherein the HDPE of the second polyethylene polymer is different than the HDPE of the first polyethylene polymer, the weight ratio of the HDPE of the first polyethylene polymer to the HDPE of the second polyethylene polymer is from 0.5 to 3:1, and wherein the total amount of HDPE present in the polymer composition is from 50 % by weight to 90 % by weight of the polymer composition.
A charging member, comprising: a support; an elastic layer; and a surface layer, wherein: the surface layer comprises a polymer compound having at least one bond selected from an Si-O-M bond and an Si-O-Ta bond, at least one bond selected from an M-O-Ge bond and a Ta-O-Ge bond, and an Si-O-Ge bond; the polymer compound has a structural unit represented by the following formula, a structural unit represented by the following formula, and at least one structural unit selected from a structural unit represented by the following formula and a structural unit represented by the following formula; and the charging member has a crack extending from a surface thereof to the elastic layer, and the crack has a convexly raised edge by which the surface of the charging member is roughened, provided that M represents any element selected from the group consisting of Ti, Zr, and Hf: in the formula, R 1 and R 2 each independently represent any one of the following formulae to: in the formulae to, R 3 to R 7, R 10 to R 14, R 19, R 20, R 25, and R 26 each independently represent a hydrogen atom, an alkyl group having 1 or more and 4 or less carbon atoms, a hydroxyl group, a carboxyl group, or an amino group, R 2, R 9, R 15 to R 18, R 23, R 24, and R 29 to R 32 each independently represent a hydrogen atom or an alkyl group having 1 or more and 4 or less carbon atoms, R 21, R 22, R 27, and R 28 each independently represent a hydrogen atom, an alkoxyl group having 1 or more and 4 or less carbon atoms, or an alkyl group having 1 or more and 4 or less carbon atoms, n, m, l, q, s, and t each independently represent an integer of 1 or more and 8 or less, p and r each independently represent an integer of 4 or more and 12 or less, x and y each independently represent 0 or 1, and * and ** represent sites to be bonded to a silicon atom and an oxygen atom in the formula, respectively: Formula GeO) 4/2 Formula MO 4/2 Formula TaO 5/2 in the formula, M represents any element selected from the group consisting of Ti, Zr, and Hf. a support; an elastic layer; and a surface layer, the surface layer comprises a polymer compound having at least one bond selected from an Si-O-M bond and an Si-O-Ta bond, at least one bond selected from an M-O-Ge bond and a Ta-O-Ge bond, and an Si-O-Ge bond; the polymer compound has a structural unit represented by the following formula, a structural unit represented by the following formula, and at least one structural unit selected from a structural unit represented by the following formula and a structural unit represented by the following formula; and the charging member has a crack extending from a surface thereof to the elastic layer, and the crack has a convexly raised edge by which the surface of the charging member is roughened, provided that M represents any element selected from the group consisting of Ti, Zr, and Hf:
A method for producing or machining gears on workpieces, wherein a rolling first machining engagement between a machining tool (WF; WS) in the form of a hob, grinding worm, honing tool, power-skiving or hard skiving tool or shaving tool, driven around its axis of rotation by means of a tool-side spindle drive motor, and a first workpiece, which is rotatable around the axis of rotation of a first workpiece-side spindle, is performed at a first location on a gear-cutting machine (100; 200), and wherein a second machining engagement is performed at a second workpiece, different from the first workpiece, which is rotatable around the axis of rotation of a second workpiece-side spindle that is different from the first workpiece-side spindle, wherein the first and/or second workpiece-side spindle is fixed in space or is movable along its axis (Z11, Z12) and the machining tool can execute, relative to the first workpiece-side spindle, a movement, serving as an axial infeed movement in the first machining engagement, along a tool-side machine axis that has a directional component in the direction of the first workpiece-side spindle axis and in particular extends parallel thereto, a movement along a radial axis extending orthogonally to this machine axis and to the tool axis of rotation, and a tangential movement along the axial direction of the tool axis of rotation, the position of which is not fixed in space due to a pivotability of the machining tool around a pivot axis, wherein after the first machining engagement, a tool-side positioning movement which takes place along this tool-side machine axis and allows the second machining engagement is carried out, wherein the second machining engagement is a machining engagement that is identical to the first machining engagement in terms of type of machining, is effected using the same tool-side spindle drive motor as in the first machining, is performed with the same machining tool (WF; WS) rotating around the same axis of rotation as in the first machining engagement, and is carried out in the gear-cutting machine at a second location that is different from the first location.
Method of obtaining gesture zone definition data for a control system based on user input, wherein said user input is obtained through a mobile communication device external to said control system, the method comprising: receiving, by a sensor device, a sensor signal and determining from the sensor signal, by a controller comprised by the control system or located in the mobile communication device, a location data of the mobile communication device; providing, through the mobile communication device, a feedback signal in response to said determining of the location data, the feedback signal providing feedback information on said location data; receiving, via an input unit of the mobile communication device, an input signal indicative of an instruction command, and determining, by the controller, based on said instruction command, the gesture zone definition data. receiving, by a sensor device, a sensor signal and determining from the sensor signal, by a controller comprised by the control system or located in the mobile communication device, a location data of the mobile communication device; providing, through the mobile communication device, a feedback signal in response to said determining of the location data, the feedback signal providing feedback information on said location data; receiving, via an input unit of the mobile communication device, an input signal indicative of an instruction command, and determining, by the controller, based on said instruction command, the gesture zone definition data.
An embolotherapy product, comprising a particulate formulation comprising a biocompatible, bioresorbable polymer comprising one or more units described by Formula: and optionally including stereoisomers thereof, wherein X = I or Br; Y1 and Y2 can independently = 0, 1, 2, 3 or 4; wherein f is between 0 and less than 1; g is between 0 and 1, inclusive; and f + g is between 0 and 1, inclusive; wherein A is selected from the group consisting of: wherein R 1 is independently an H or alkyl having 1 to 18 carbon atoms and containing from 0 to 5 heteroatoms selected from O and N; R 3 is a saturated or unsaturated, substituted or unsubstituted alkyl, aryl, or alkylaryl group containing up to 18 carbon atoms and 0 to 8 heteroatoms selected from O and N; B is an aliphatic linear or branched diol or a poly(alkylene glycol) unit; and wherein R and R 2 are independently selected from: wherein R 7 is selected from the group consisting of -CH=CH-, -CHJ 1 -CHJ 2 - and (-CH 2 -)a; wherein R 8 is selected from the group consisting of -CH=CH-, -CHJ 1 -CHJ 2 - and (-CH 2 -)n; wherein a and n are independently between 0 and 8 inclusive; J 1 and J 2 are independently Br or I; and wherein Q for R 2 comprises a free carboxylic acid group and Q for each R is independently selected from the group consisting of hydrogen and carboxylic acid esters and amides, wherein said esters and amides are selected from the group consisting of esters and amides of alkyl and alkylaryl groups containing up to 18 carbon atoms and esters and amides of biologically and pharmaceutically active compounds; wherein the polymer comprises a sufficient number of halogen atoms to render the embolotherapy product inherently radiopaque. wherein X = I or Br; Y1 and Y2 can independently = 0, 1, 2, 3 or 4; wherein f is between 0 and less than 1; g is between 0 and 1, inclusive; and f + g is between 0 and 1, inclusive; wherein A is selected from the group consisting of: wherein R 1 is independently an H or alkyl having 1 to 18 carbon atoms and containing from 0 to 5 heteroatoms selected from O and N; R 3 is a saturated or unsaturated, substituted or unsubstituted alkyl, aryl, or alkylaryl group containing up to 18 carbon atoms and 0 to 8 heteroatoms selected from O and N; B is an aliphatic linear or branched diol or a poly(alkylene glycol) unit; and wherein R and R 2 are independently selected from: wherein R 7 is selected from the group consisting of -CH=CH-, -CHJ 1 -CHJ 2 - and (-CH 2 -)a; wherein R 8 is selected from the group consisting of -CH=CH-, -CHJ 1 -CHJ 2 - and (-CH 2 -)n; wherein a and n are independently between 0 and 8 inclusive; J 1 and J 2 are independently Br or I; and wherein Q for R 2 comprises a free carboxylic acid group and Q for each R is independently selected from the group consisting of hydrogen and carboxylic acid esters and amides, wherein said esters and amides are selected from the group consisting of esters and amides of alkyl and alkylaryl groups containing up to 18 carbon atoms and esters and amides of biologically and pharmaceutically active compounds;
Corner connector for positive plug-in connection of two profile strips (2, 3) in a frame corner of a frame system, - wherein the corner connector has a first joining leg and a second joining leg joinable therewith, - wherein the joining legs (6, 7) have a first leg section (6a, 7a) for connection to the profile strip (2, 3) and a second leg section (6b, 7b) with a polygonal joining contour (6c, 7c), - wherein the first joining leg has a first joining contour and the second joining leg has a second joining contour corresponding to the first joining contour, characterized in - that the joining contour of the first joining leg is an opening contour, and - that the joining contour of the second joining leg is a joining pin, which engages positively in the joining contour, designed as an opening contour, of the first joining leg. - wherein the corner connector has a first joining leg and a second joining leg joinable therewith, - wherein the joining legs (6, 7) have a first leg section (6a, 7a) for connection to the profile strip (2, 3) and a second leg section (6b, 7b) with a polygonal joining contour (6c, 7c), - wherein the first joining leg has a first joining contour and the second joining leg has a second joining contour corresponding to the first joining contour, characterized in - that the joining contour of the first joining leg is an opening contour, and - that the joining contour of the second joining leg is a joining pin, which engages positively in the joining contour, designed as an opening contour, of the first joining leg.