A system for treating a subject, the system comprising: an elongate assembly configured to be positioned in a lumen of an airway of a bronchial tree, the elongate assembly including a shaft selectively positionable in the lumen of the airway, and a pluarality of radially deployable ablation assemblies coupled to the shaft, each of the ablation assemblies including a protective section, and an embeddable ablation element adapted to ablate targeted nerve tissue of a nerve trunk extending along the airway to attenuate signals transmitted through the nerve trunk while preventing or limiting damage to an inner surface of the airway, wherein the ablation element and the protective section cooperate to selectively damage the targeted nerve tissue while injury to non-target tissue is minimized, wherein the deployable ablation assemblies are coupled to the distal end of the shaft and are selectively deployable relative to the distal end of the shaft in longitudinal direction of the shaft and between a retracted configuration and a deployed configuration, wherein the retracted configuration is a configuration in which the deployable ablation assemblies are collapsed inwardly with respect to the inner surface of the airway, and the deployed configuration is a configuration in which the deployable ablation assemblies are biased radially outward toward the inner surface of the airway and the embeddable ablation element and at least a portion of the protective section is configured to be embedded in wall tissue of the airway near the nerve trunk, wherein, in the retracted configuration, at least a portion of the deployable ablation assemblies are positioned within the distal end of the shaft, and wherein a first number of the ablation assemblies are connected to a first lead of a radiofrequency generator while a second plurality of ablation assemblies are connected to a second lead of the radiofrequency generator such that current flows between the ablation assemblies. an elongate assembly configured to be positioned in a lumen of an airway of a bronchial tree, the elongate assembly including a shaft selectively positionable in the lumen of the airway, and a pluarality of radially deployable ablation assemblies coupled to the shaft, each of the ablation assemblies including a protective section, and an embeddable ablation element adapted to ablate targeted nerve tissue of a nerve trunk extending along the airway to attenuate signals transmitted through the nerve trunk while preventing or limiting damage to an inner surface of the airway, wherein the ablation element and the protective section cooperate to selectively damage the targeted nerve tissue while injury to non-target tissue is minimized, wherein the deployable ablation assemblies are coupled to the distal end of the shaft and are selectively deployable relative to the distal end of the shaft in longitudinal direction of the shaft and between a retracted configuration and a deployed configuration, wherein the retracted configuration is a configuration in which the deployable ablation assemblies are collapsed inwardly with respect to the inner surface of the airway, and the deployed configuration is a configuration in which the deployable ablation assemblies are biased radially outward toward the inner surface of the airway and the embeddable ablation element and at least a portion of the protective section is configured to be embedded in wall tissue of the airway near the nerve trunk, wherein, in the retracted configuration, at least a portion of the deployable ablation assemblies are positioned within the distal end of the shaft, and wherein a first number of the ablation assemblies are connected to a first lead of a radiofrequency generator while a second plurality of ablation assemblies are connected to a second lead of the radiofrequency generator such that current flows between the ablation assemblies.