A compound of the general formula: or a pharmacologically acceptable salt thereof, wherein A represents a group of the formula: R 1, R 2 and R 3, in each case, independently represents a hydrogen atom, a halogen atom, CN, CF 3, NO 2, NH 2,-NHC(=O)R 4, -NHSO 2 R 4, -(CH 2) m -L 1 -W, -O(CH 2) m -L 2 -W, -C (CH 2) m -L 3 -W, -OC (CH 2) m -L 3 -W, OC 2 (CH 2) m -L 3 -W, -(C 5-6 heterocyclyl)-L 4 -W, SOCH 3, SOCN, SOCF 3, SO 2 CH 3, SO 2 CN, SO 2 CF 3, SO 2 NR 5 R 6, C(=O)NR 5 R 6, COCH 3, COCF 3, C 3, or R 4, in each case, independently represents a hydrogen atom; an alkyl; alkenyl; alkynyl; heteroalkyl; cycloalkyl; heterocycloalkyl; aryl; heteroaryl; aralkyl; or heteroaralkyl group; R 5 and R 6 each independently represents a hydrogen atom; or - (CH 2) m -L 5; or R 5 and R 6 are taken together to form a 5- to 8-membered saturated, unsaturated or aromatic heterocycle containing 1 to 4 N atoms or 1 to 3 heteroatoms selected from the group consisting of nitrogen, oxygen and sulphur, which heterocycle may be unsubstituted or mono-, di or trisubstituted by halogen atom or L 5; or R 5 and R 6 are taken together to form a 5- to 8-membered saturated, unsaturated or aromatic heterocycle containing 1 to 3 heteroatoms selected from the group consisting of nitrogen, oxygen and sulphur, which is fused to one or two rings selected from the group consisting of cycloalkyl; heterocycloalkyl; alkylcycloalkyl; heteroalkylcycloalkyl; aryl; heteroaryl; aralkyl; and heteroaralkyl; L 1, L 2, L 3 and L 4, in each case, independently represents a single bond, O, S, NH, SO, SO 2, -O(CH 2 CH 2 O) n -, -(OCH 2 CH 2) n -, or-[C CH 2 -(OCH 2 CH 2) 2 -NH] n -; L 5 represents H; -(CH 2) p -L 6; -(CH 2) p -OL 6; a C 1-6 heteroalkyl; a cycloalkyl; a heterocycloalkyl; an alkylcycloalkyl; a heteroalkylcycloalkyl; an aryl; a heteroaryl; an aralkyl; or a heteroaralkyl group; L 6 represents a C 1-6 alkyl, C 3-6 alkenyl, or C 3-6 alkynyl group, in which 1 to 5 H atoms may, independently of each other, be replaced by halogen atom, CN, CF 3, NO 2, OR or NHR, and/or in which one or two non-adjacent CH 2 group(s) may be replaced by O, NH, S, SO, SO 2, or C 3-7 cycloalkyl; W represents a hydrogen atom; a C 1-6 alkyl, C 3-6 alkenyl, or C 3-6 alkynyl group, in which 1 to 5 H atoms may, independently of each other, be replaced by halogen atom, CN, CF 3, NO 2, OR or NHR, and/or in which one or two non-adjacent CH 2 group(s) may be replaced by O, NH, S, SO, SO 2, or C 3-7 cycloalkyl; NR 5 R 6,-NHC(=O)R 4, -NHSO 2 R 4, -C R 5, - [(CH 2) m C OR 4] 2; or a 5, 6, or 7-membered saturated, unsaturated or aromatic carbocyclic or heterocyclic ring, optionally substituted by 1, 2, or 3 R 7; R 7, in each case, independently represents a halogen atom, an oxygen atom, a sulphur atom, CN, CF 3, NH 2, or NO 2; X 1, X 2, and X 3 each independently represents H or CH 3; m each independently is 0, 1, 2, 3, or 4; n each independently is an integer from 1 to 40; and p each independently is 0, 1, 2 or 3. R 4, in each case, independently represents a hydrogen atom; an alkyl; alkenyl; alkynyl; heteroalkyl; cycloalkyl; heterocycloalkyl; aryl; heteroaryl; aralkyl; or heteroaralkyl group; R 5 and R 6 each independently represents a hydrogen atom; or - (CH 2) m -L 5; or R 5 and R 6 are taken together to form a 5- to 8-membered saturated, unsaturated or aromatic heterocycle containing 1 to 4 N atoms or 1 to 3 heteroatoms selected from the group consisting of nitrogen, oxygen and sulphur, which heterocycle may be unsubstituted or mono-, di or trisubstituted by halogen atom or L 5; or R 5 and R 6 are taken together to form a 5- to 8-membered saturated, unsaturated or aromatic heterocycle containing 1 to 3 heteroatoms selected from the group consisting of nitrogen, oxygen and sulphur, which is fused to one or two rings selected from the group consisting of cycloalkyl; heterocycloalkyl; alkylcycloalkyl; heteroalkylcycloalkyl; aryl; heteroaryl; aralkyl; and heteroaralkyl; L 1, L 2, L 3 and L 4, in each case, independently represents a single bond, O, S, NH, SO, SO 2, -O(CH 2 CH 2 O) n -, -(OCH 2 CH 2) n -, or-[C CH 2 -(OCH 2 CH 2) 2 -NH] n -; L 5 represents H; -(CH 2) p -L 6; -(CH 2) p -OL 6; a C 1-6 heteroalkyl; a cycloalkyl; a heterocycloalkyl; an alkylcycloalkyl; a heteroalkylcycloalkyl; an aryl; a heteroaryl; an aralkyl; or a heteroaralkyl group; L 6 represents a C 1-6 alkyl, C 3-6 alkenyl, or C 3-6 alkynyl group, in which 1 to 5 H atoms may, independently of each other, be replaced by halogen atom, CN, CF 3, NO 2, OR or NHR, and/or in which one or two non-adjacent CH 2 group(s) may be replaced by O, NH, S, SO, SO 2, or C 3-7 cycloalkyl; W represents a hydrogen atom; a C 1-6 alkyl, C 3-6 alkenyl, or C 3-6 alkynyl group, in which 1 to 5 H atoms may, independently of each other, be replaced by halogen atom, CN, CF 3, NO 2, OR or NHR, and/or in which one or two non-adjacent CH 2 group(s) may be replaced by O, NH, S, SO, SO 2, or C 3-7 cycloalkyl; NR 5 R 6,-NHC(=O)R 4, -NHSO 2 R 4, -C R 5, - [(CH 2) m C OR 4] 2; or a 5, 6, or 7-membered saturated, unsaturated or aromatic carbocyclic or heterocyclic ring, optionally substituted by 1, 2, or 3 R 7; R 7, in each case, independently represents a halogen atom, an oxygen atom, a sulphur atom, CN, CF 3, NH 2, or NO 2; X 1, X 2, and X 3 each independently represents H or CH 3; m each independently is 0, 1, 2, 3, or 4; n each independently is an integer from 1 to 40; and p each independently is 0, 1, 2 or 3.