A compound according to Formula: or stereoisomers, tautomers, a pharmaceutically acceptable salts, or solvates thereof, wherein R 2 is independently selected from H and C 1-4 alkyl substituted with 1-5 R 9; R 13 is independently selected from H, D, and C 1-4 alkyl substituted with 1-3 R 9; R 3 and R 4 are independently selected from H, C 1-7 alkyl substituted with 1-3 R 9, - (CR 7 R 7) r -C 3-8 cycloalkyl substituted with 1-3 R 8, -(CR 7 R 7) r -aryl substituted with 1-3 R 8, C 2-7 alkenyl substituted with 1-3 R 9, -(CR 7 R 7) r -5-6 membered heterocyclic ring substituted with 1-3 R 8, -(CR 7 R 7) r -5-6 membered heteroaryl ring substituted with 1-3 R 8, or R 3 and R 4 combine with the N to which they are attached to form a 4-9 membered heterocyclic ring substituted with 1-3 R 8; X 1, X 2, X 3, and X 4 are independently selected from CR 5 and N; provided no more than two of X 1, X 2, X 3, or X 4 are N; R 5 is independently selected from H, F, Cl, OR 7, CN, N(R 7) 2, C 1-4 alkyl substituted with 1-5 R 9, C 1-4 alkoxy substituted with 1-5 R 9, and C 1-4 heteroalkyl substituted with 1-5 R 9; R 6 is C 3-8 cycloalkyl which is substituted with R 10 and (-CH 2) 0-1 R 11; R 7 is independently selected from H, C 1-4 alkyl, and C 3-6 cycloalkyl; or R 7 and R 7, together with the carbon atom to which they both attach, form a C 3-6 cycloalkyl ring; R 8 is independently selected from H, D, C 1-6 alkyl substituted with 1-5 R 9, C 2-6 alkenyl, C 2-6 alkynyl, phenyl, -(CH 2) r -C 3-6 cycloalkyl, F, Cl, Br, CN, COOH, and C 1-4 alkoxy; R 9 is independently selected from H, D, F, Cl, NH 2, OH, OC 1-5 alkyl, C 1-5 alkyl, C 1-5 heteroalkyl C 3-6 cycloalkyl, and phenyl, wherein when R 9 is Cl, NH 2 or OH it is not substituted on C 1 of the the alkyl to which it is attached; R 10 is independently selected from H, D, C 1-4 alkyl, F, Cl, Br, OR 7, NHC(=O)OR 7, and NHC(=O)OR 7; R 11 is independently selected from H, CN, -C(=O)R 12, tetrazolyl, and R 12 is independently selected from OH, OC 1-4 alkyl, NH 2, NHCH 2 CH 2 SO 3 H, and NHSO 2 C 1-4 alky; r is independently selected from zero, 1, 2, 3, and 4, and n is slected from 1, 2, 3, or 4. R 2 is independently selected from H and C 1-4 alkyl substituted with 1-5 R 9; R 13 is independently selected from H, D, and C 1-4 alkyl substituted with 1-3 R 9; R 3 and R 4 are independently selected from H, C 1-7 alkyl substituted with 1-3 R 9, - (CR 7 R 7) r -C 3-8 cycloalkyl substituted with 1-3 R 8, -(CR 7 R 7) r -aryl substituted with 1-3 R 8, C 2-7 alkenyl substituted with 1-3 R 9, -(CR 7 R 7) r -5-6 membered heterocyclic ring substituted with 1-3 R 8, -(CR 7 R 7) r -5-6 membered heteroaryl ring substituted with 1-3 R 8, or R 3 and R 4 combine with the N to which they are attached to form a 4-9 membered heterocyclic ring substituted with 1-3 R 8; X 1, X 2, X 3, and X 4 are independently selected from CR 5 and N; provided no more than two of X 1, X 2, X 3, or X 4 are N; R 5 is independently selected from H, F, Cl, OR 7, CN, N(R 7) 2, C 1-4 alkyl substituted with 1-5 R 9, C 1-4 alkoxy substituted with 1-5 R 9, and C 1-4 heteroalkyl substituted with 1-5 R 9; R 6 is C 3-8 cycloalkyl which is substituted with R 10 and (-CH 2) 0-1 R 11; R 7 is independently selected from H, C 1-4 alkyl, and C 3-6 cycloalkyl; or R 7 and R 7, together with the carbon atom to which they both attach, form a C 3-6 cycloalkyl ring; R 8 is independently selected from H, D, C 1-6 alkyl substituted with 1-5 R 9, C 2-6 alkenyl, C 2-6 alkynyl, phenyl, -(CH 2) r -C 3-6 cycloalkyl, F, Cl, Br, CN, COOH, and C 1-4 alkoxy; R 9 is independently selected from H, D, F, Cl, NH 2, OH, OC 1-5 alkyl, C 1-5 alkyl, C 1-5 heteroalkyl C 3-6 cycloalkyl, and phenyl, wherein when R 9 is Cl, NH 2 or OH it is not substituted on C 1 of the the alkyl to which it is attached; R 10 is independently selected from H, D, C 1-4 alkyl, F, Cl, Br, OR 7, NHC(=O)OR 7, and NHC(=O)OR 7; R 11 is independently selected from H, CN, -C(=O)R 12, tetrazolyl, and R 12 is independently selected from OH, OC 1-4 alkyl, NH 2, NHCH 2 CH 2 SO 3 H, and NHSO 2 C 1-4 alky; r is independently selected from zero, 1, 2, 3, and 4, and n is slected from 1, 2, 3, or 4.