An aerosol delivery unit (10, 210, 410) for selectively delivering a dose of aerosolized matter, the aerosol delivery unit (10, 210, 410) comprising: a base housing (12, 212, 412); an actuator assembly provided in the base housing (12, 212, 412); and a removable cartridge assembly (14, 214, 414) coupled to the base housing (12, 212, 412) and interfacing with the actuator assembly, the removable cartridge assembly (14, 214, 414) including: a canister (16, 216, 416) containing matter to be aerosolized; and a cartridge unit within which the canister (16, 216, 416) is loaded, the cartridge unit including a cartridge body (90, 290, 430) having a mouthpiece aperture (92, 292, 432) through which to inhale the dose of aerosolized matter released from the canister (16, 216, 416), one or more intake apertures (94, 294, 436) through which air can enter the cartridge unit, and an inhalation passageway (96, 296, 434) extending from a location of the one or more intake apertures (94, 294, 436) to a location of the mouthpiece aperture (92, 292) and being in fluid communication with a discharge outlet (98, 438) of the canister (16, 216, 416), and characterized in that the cartridge unit further includes a power source (120, 320, 440) carried by the cartridge body (90, 290, 430) for powering the actuator assembly provided in the base housing (12, 212, 412) adjacent the removable cartridge assembly (14, 214, 414). a base housing (12, 212, 412); an actuator assembly provided in the base housing (12, 212, 412); and a removable cartridge assembly (14, 214, 414) coupled to the base housing (12, 212, 412) and interfacing with the actuator assembly, the removable cartridge assembly (14, 214, 414) including: a canister (16, 216, 416) containing matter to be aerosolized; and a cartridge unit within which the canister (16, 216, 416) is loaded, the cartridge unit including a cartridge body (90, 290, 430) having a mouthpiece aperture (92, 292, 432) through which to inhale the dose of aerosolized matter released from the canister (16, 216, 416), one or more intake apertures (94, 294, 436) through which air can enter the cartridge unit, and an inhalation passageway (96, 296, 434) extending from a location of the one or more intake apertures (94, 294, 436) to a location of the mouthpiece aperture (92, 292) and being in fluid communication with a discharge outlet (98, 438) of the canister (16, 216, 416), and characterized in that the cartridge unit further includes a power source (120, 320, 440) carried by the cartridge body (90, 290, 430) for powering the actuator assembly provided in the base housing (12, 212, 412) adjacent the removable cartridge assembly (14, 214, 414). a canister (16, 216, 416) containing matter to be aerosolized; and a cartridge unit within which the canister (16, 216, 416) is loaded, the cartridge unit including a cartridge body (90, 290, 430) having a mouthpiece aperture (92, 292, 432) through which to inhale the dose of aerosolized matter released from the canister (16, 216, 416), one or more intake apertures (94, 294, 436) through which air can enter the cartridge unit, and an inhalation passageway (96, 296, 434) extending from a location of the one or more intake apertures (94, 294, 436) to a location of the mouthpiece aperture (92, 292) and being in fluid communication with a discharge outlet (98, 438) of the canister (16, 216, 416), and characterized in that the cartridge unit further includes a power source (120, 320, 440) carried by the cartridge body (90, 290, 430) for powering the actuator assembly provided in the base housing (12, 212, 412) adjacent the removable cartridge assembly (14, 214, 414).