An organ perfusion device, comprising: a disposable assembly comprising: (i) an inlet for connection to the organ, and an outlet for connection to the organ; (ii) a perfusion circuit including: a reservoir configured to hold a perfusion fluid; a waste receptacle; a plurality of fluid conduits defining: a delivery fluid path connecting the reservoir with the inlet; a return fluid path, independent of the delivery fluid path, connecting the reservoir with the outlet; and a waste fluid path connecting the reservoir with the waste receptacle; a reusable assembly including a dock configured to releasably support the disposable assembly in an operational state; the reusable assembly further comprising: (iii) a first flow control device configured to selectively prevent or allow fluid flow from the reservoir to the organ via the delivery fluid path; and (iv) a second flow control device configured to selectively prevent or allow fluid flow from the reservoir to the waste receptacle via the waste fluid path; characterized in that the first flow control device and the second flow control device are mounted within the reusable assembly in order to be brought into contact with the appropriate fluid conduits of the disposable assembly when the disposable assembly is installed within the dock, and configured to selectively prevent or allow fluid flow via the delivery fluid path and the waste fluid path respectively without direct contact with the perfusion fluid. a disposable assembly comprising: (i) an inlet for connection to the organ, and an outlet for connection to the organ; (ii) a perfusion circuit including: a reservoir configured to hold a perfusion fluid; a waste receptacle; a plurality of fluid conduits defining: a delivery fluid path connecting the reservoir with the inlet; a return fluid path, independent of the delivery fluid path, connecting the reservoir with the outlet; and a waste fluid path connecting the reservoir with the waste receptacle; (i) an inlet for connection to the organ, and an outlet for connection to the organ; (ii) a perfusion circuit including: a reservoir configured to hold a perfusion fluid; a waste receptacle; a plurality of fluid conduits defining: a delivery fluid path connecting the reservoir with the inlet; a return fluid path, independent of the delivery fluid path, connecting the reservoir with the outlet; and a waste fluid path connecting the reservoir with the waste receptacle; a reservoir configured to hold a perfusion fluid; a waste receptacle; a plurality of fluid conduits defining: a delivery fluid path connecting the reservoir with the inlet; a return fluid path, independent of the delivery fluid path, connecting the reservoir with the outlet; and a waste fluid path connecting the reservoir with the waste receptacle; a delivery fluid path connecting the reservoir with the inlet; a return fluid path, independent of the delivery fluid path, connecting the reservoir with the outlet; and a waste fluid path connecting the reservoir with the waste receptacle; a reusable assembly including a dock configured to releasably support the disposable assembly in an operational state; the reusable assembly further comprising: (iii) a first flow control device configured to selectively prevent or allow fluid flow from the reservoir to the organ via the delivery fluid path; and (iv) a second flow control device configured to selectively prevent or allow fluid flow from the reservoir to the waste receptacle via the waste fluid path; characterized in that the first flow control device and the second flow control device are mounted within the reusable assembly in order to be brought into contact with the appropriate fluid conduits of the disposable assembly when the disposable assembly is installed within the dock, and configured to selectively prevent or allow fluid flow via the delivery fluid path and the waste fluid path respectively without direct contact with the perfusion fluid. (iii) a first flow control device configured to selectively prevent or allow fluid flow from the reservoir to the organ via the delivery fluid path; and (iv) a second flow control device configured to selectively prevent or allow fluid flow from the reservoir to the waste receptacle via the waste fluid path; characterized in that the first flow control device and the second flow control device are mounted within the reusable assembly in order to be brought into contact with the appropriate fluid conduits of the disposable assembly when the disposable assembly is installed within the dock, and configured to selectively prevent or allow fluid flow via the delivery fluid path and the waste fluid path respectively without direct contact with the perfusion fluid.