mhurhangee/ep-ind-claims huggingface dataset:
An oil-in-water nanoemulsion composition having a continuous aqueous phase and dispersed oil droplets, wherein the nanoemulsion comprises: (a) a therapeutically effective amount of clobetasol or a pharmaceutically acceptable salt or ester thereof; (b) one or more oil components; and (c) one or more surfactants; together with one or more pharmaceutically acceptable excipients or carriers wherein: the osmolality of the nanoemulsion composition is comprised from 100 mOsm/Kg to 500 mOsm/Kg; the droplet average size is comprised from 1 nm to 500 nm measured by Dynamic light scattering; the weight ratio between the oil components and the sum of the oil components and one or more surfactants is comprised from 0.001 to 0.5; the weight ratio between the oil component and clobetasol or a pharmaceutically acceptable salt or ester thereof is comprised from 1:1 to 200:1; and the weight ratio between the surfactant and clobetasol or a pharmaceutically acceptable salt or ester thereof is comprised from 2:1 to 200:1. (a) a therapeutically effective amount of clobetasol or a pharmaceutically acceptable salt or ester thereof; (b) one or more oil components; and (c) one or more surfactants; the osmolality of the nanoemulsion composition is comprised from 100 mOsm/Kg to 500 mOsm/Kg; the droplet average size is comprised from 1 nm to 500 nm measured by Dynamic light scattering; the weight ratio between the oil components and the sum of the oil components and one or more surfactants is comprised from 0.001 to 0.5; the weight ratio between the oil component and clobetasol or a pharmaceutically acceptable salt or ester thereof is comprised from 1:1 to 200:1; and the weight ratio between the surfactant and clobetasol or a pharmaceutically acceptable salt or ester thereof is comprised from 2:1 to 200:1.
A method, comprising: forming a pocket and a receptacle in an end portion of a first panel, the pocket having an end opening and being contiguous with the receptacle; coupling a magnet within the receptacle; forming a pocket within a second panel that terminates at an end face of the second panel; coupling a first shield portion of a ferromagnetic shield in the pocket of the second panel such that a second shield portion of the ferromagnetic shield extends from the end face of the second panel, an inner shield surface of the ferromagnetic shield being substantially flush with an inner second panel surface of the second panel; and disposing the second shield portion of the ferromagnetic shield within the pocket of the first panel via the end opening to form a magnetic lap joint, wherein the inner shield surface and the inner second panel surface are substantially flush with an inner first panel surface of the first panel. forming a pocket and a receptacle in an end portion of a first panel, the pocket having an end opening and being contiguous with the receptacle; coupling a magnet within the receptacle; forming a pocket within a second panel that terminates at an end face of the second panel; coupling a first shield portion of a ferromagnetic shield in the pocket of the second panel such that a second shield portion of the ferromagnetic shield extends from the end face of the second panel, an inner shield surface of the ferromagnetic shield being substantially flush with an inner second panel surface of the second panel; and disposing the second shield portion of the ferromagnetic shield within the pocket of the first panel via the end opening to form a magnetic lap joint, wherein the inner shield surface and the inner second panel surface are substantially flush with an inner first panel surface of the first panel.
A pharmaceutical kit comprising: a) a first composition comprising a gas-filled microvesicle, or a precursor thereof, having a stabilizing envelope comprising a plurality of polymer molecules, said polymer being a polyethylene glycol comprising repeating oxyethylene units, said precursor comprising stabilizing amphiphilic materials in dry powdered form capable of forming said stabilizing envelope upon reconstitution with an aqueous carrier; and b) a second composition comprising a targeting construct, said construct comprising a targeting ligand associated with an anti-polymer antibody capable of selectively binding to said polymer. a) a first composition comprising a gas-filled microvesicle, or a precursor thereof, having a stabilizing envelope comprising a plurality of polymer molecules, said polymer being a polyethylene glycol comprising repeating oxyethylene units, said precursor comprising stabilizing amphiphilic materials in dry powdered form capable of forming said stabilizing envelope upon reconstitution with an aqueous carrier; and b) a second composition comprising a targeting construct, said construct comprising a targeting ligand associated with an anti-polymer antibody capable of selectively binding to said polymer.
An azeotrope-like composition comprising an effective amount of trans-1,3,3,3-tetrafluoropropene combined with an effective amount of an alcohol selected from the group consisting of methanol, ethanol, propanol, isopropanol, tert-butanol, isobutanol, 2-ethyl hexanol, and any combination thereof, wherein said alcohol is present in said composition in an amount from greater than 0 to about 25 weight percent, and wherein said trans-1,3,3,3-tetrafluoropropene is present in said composition in an amount from about 75 to less than 100 weight percent.
A thermosensitive recording medium comprising a support, a thermosensitive recording layer installed on the support, comprising a colorless or pale colored electron donating leuco dye and an electron accepting color developing agent, and a protective layer on the thermosensitive recording layer, wherein the thermosensitive recording layer comprises, as the electron accepting color developing agent, (i) a sulfonic acid compound represented by the following formula (formula 1) and (ii) a diphenyl sulfone compound represented by the following formula (formula 2) wherein R 1 represents a hydroxyl group or a group represented by the following formula (formula 3), R 2 represents -OR 5 (wherein R 5 represents a linear or branched, saturated or unsaturated hydrocarbon having 1 to 4 carbons) or a group represented by the above formula 3, R 3 and R 4 each independently represent an alkyl group or an alkenyl group, and m and n each independently represent 0 or 1, wherein both of the thermosensitive recording layer and the protective layer respectively comprise crosslinking agents, and at least one of the thermosensitive recording layer and the protective layer comprises an ammonium zirconium carbonate as the crosslinking agent. R 1 represents a hydroxyl group or a group represented by the following formula (formula 3), R 2 represents -OR 5 (wherein R 5 represents a linear or branched, saturated or unsaturated hydrocarbon having 1 to 4 carbons) or a group represented by the above formula 3, R 3 and R 4 each independently represent an alkyl group or an alkenyl group, and m and n each independently represent 0 or 1,
Capsule for cleaning a brewing chamber of a beverage preparation machine, comprising a cup-shaped container having an outwardly projecting edge which is sealed at an upper side by a releasable cover, and contains at least one cleaning agent, whereby a screen, a mesh or a water-soluble film is provided on the container underneath the cover, which covers an opening of the container and is fixed to the outwardly projecting edge and by means of which the cleaning agent is held within the container.
A service trolley (100, 200) for use in a craft, the trolley (100, 200) comprising: a container (101, 201) for storing chilled meals (114, 214); a plurality of wheels (102, 202) attached with the container (101, 201) and configured to support the container (101, 201) relative to a support surface and to facilitate movement of the container (101, 201) relative to the support surface; and a power source (103, 203) housed at least partially on or at least partially within the container (101, 201) and configured for providing power to at least one system of the trolley (100, 200) housed at least partially on or at least partially within the container (100, 200); a cooling system (105, 205) for cooling chilled meals (114, 214) stored in the container; said cooling system (105, 205) is powered by the power source (103, 203); characterised in that; the service trolley (100, 200) further comprises a heating system (104, 204) for heating the chilled meals stored in the container (101, 201); said heating system (104, 204) is powered by the power source (103, 203). a container (101, 201) for storing chilled meals (114, 214); a plurality of wheels (102, 202) attached with the container (101, 201) and configured to support the container (101, 201) relative to a support surface and to facilitate movement of the container (101, 201) relative to the support surface; and a power source (103, 203) housed at least partially on or at least partially within the container (101, 201) and configured for providing power to at least one system of the trolley (100, 200) housed at least partially on or at least partially within the container (100, 200); a cooling system (105, 205) for cooling chilled meals (114, 214) stored in the container; said cooling system (105, 205) is powered by the power source (103, 203); characterised in that; the service trolley (100, 200) further comprises a heating system (104, 204) for heating the chilled meals stored in the container (101, 201); said heating system (104, 204) is powered by the power source (103, 203).
A method for managing a service cartridge for an inkjet printhead, wherein the service cartridge comprises a printing fluid storage container for receiving printing fluid discharged from the printhead and a web wipe intended to be advanced a predetermined length for performing a wiping operation on the printhead, the method comprising: monitoring an amount of discharged printing fluid into the printing fluid storage container; monitoring an amount of consumed web wipe; and causing that in a subsequent wiping operation the web wipe is advanced a length that is higher than the predetermined length, if the ratio of the amount of discharged printing fluid to the capacity of the printing fluid storage container is higher than the ratio of the amount of consumed web wipe to the total length of the web wipe. monitoring an amount of discharged printing fluid into the printing fluid storage container; monitoring an amount of consumed web wipe; and causing that in a subsequent wiping operation the web wipe is advanced a length that is higher than the predetermined length, if the ratio of the amount of discharged printing fluid to the capacity of the printing fluid storage container is higher than the ratio of the amount of consumed web wipe to the total length of the web wipe.
An article of footwear (100; 500; 600), comprising: an upper (102; 502; 602); a tubular structure (140; 530; 630) including a first end, a second end and an intermediate portion disposed between the first end and the second end; the tubular structure (140; 530; 630) forming a tunnel extending through the tubular structure (140; 530; 630) from the first end to the second end; a first tensile strand (164; 532) extending through at least a portion of the tunnel of the tubular structure (140; 530; 630); the intermediate portion of the tubular structure (140; 530; 630) further comprising a tubular portion (147; 634) and a tab portion (200; 538) that extends away from the tubular portion (147; 634); and wherein the tab portion (200; 538) is attached to the article of footwear (100; 500; 600) and anchors the tubular structure (140; 530; 630) to the article of footwear (100; 500; 600), characterized in that the article of footwear (100; 500; 600) further includes a sole structure (110; 510; 610), the sole structure (110; 510; 610) and the upper (102; 502; 602) are joined at least along a bite line (125; 615), and the tab portion is disposed between the upper (102; 502; 602) and the sole structure (110; 510; 610), or the article of footwear further includes a heel counter, and the tab portion is attached to the heel counter. an upper (102; 502; 602); a tubular structure (140; 530; 630) including a first end, a second end and an intermediate portion disposed between the first end and the second end; the tubular structure (140; 530; 630) forming a tunnel extending through the tubular structure (140; 530; 630) from the first end to the second end; a first tensile strand (164; 532) extending through at least a portion of the tunnel of the tubular structure (140; 530; 630); the intermediate portion of the tubular structure (140; 530; 630) further comprising a tubular portion (147; 634) and a tab portion (200; 538) that extends away from the tubular portion (147; 634); and wherein the tab portion (200; 538) is attached to the article of footwear (100; 500; 600) and anchors the tubular structure (140; 530; 630) to the article of footwear (100; 500; 600), characterized in that the article of footwear (100; 500; 600) further includes a sole structure (110; 510; 610), the sole structure (110; 510; 610) and the upper (102; 502; 602) are joined at least along a bite line (125; 615), and the tab portion is disposed between the upper (102; 502; 602) and the sole structure (110; 510; 610), or the article of footwear further includes a heel counter, and the tab portion is attached to the heel counter.
A method for preparing an astaxanthin-enriched feed or an astaxanthin-enriched feed component, comprising the following method steps: - Cultivation of microorganisms that produce and/or accumulate astaxanthin to provide a microorganism biomass, - feeding the microorganism biomass to insect larvae of the genus Hermetia and cultivating the insect larvae, and - processing the insect larvae into a feed or a feed component. - Cultivation of microorganisms that produce and/or accumulate astaxanthin to provide a microorganism biomass, - feeding the microorganism biomass to insect larvae of the genus Hermetia and cultivating the insect larvae, and - processing the insect larvae into a feed or a feed component.
Connecting device comprising a screw and a support (7, 70), the latter having a cavity (8, 9, 28, 29) accommodating the screw, and on introduction of the screw adjacent walls of the cavity (8, 9, 28, 29) are in frictional and/or form-locking connection with the thread of the screw, characterized in that in the cavity (8, 9, 28, 29) a membrane penetratable by the screw is arranged and is disposed substantially transversely of the screw longitudinal axis and on deformation on introduction of the screw forms an apron predominantly at least partially enclosing the thread.
An isolated subtilisin variant, wherein said subtilisin variant is a mature form having proteolytic activity and comprises an amino acid sequence comprising a combination of amino acid substitutions selected from: G020R-N043R-A230E, G020R-N043R-A230E-S242R, G020R-N043RE271L, G020R-N043R-H249R, G020R-N043R-H249R-E271L, G020R-N043R-N076D, G020R-N043R-N076D-A230E-H249R, G020R-N043R-N076D-S101G-S103A-V104I-A232V-Q245R-N269R,, G020R-N043R-N269R, G020R-N043R-R045T-A230E,, G020R-N043R-R045T-S101A-N269R, G020R-N043R-R045T-S242R, G020R-N043R-S101A-N116A-T213A-A215F, G020R-N043R-S101A-N269R, G020R-N043R-S101G-S103A-V104I-A232V-Q245R,, G020R-N043R-S212F, G020R-N043R-S212F-W241R, G020R-N043R-S242R, G020R-N043R-S242R-E271L, G020R-N043R-V244R, G020R-N043R-W241R, G020R-S024R-N043R-N076D, G020R-S024R-N043R-R045T, G020R-S024R-N043R-R045T-A215F, G020R-S024R-N043R-R045T-H249R, G020R-S024R-N043R-R045T-N076D-S242R-H249R, G020R-S024R-N043R-R045T-N116A, G020R-S024R-N043R-R045T-N116A-T213A, G020R-S024R-N043R-R045T-N116A-T213A-A215F, G020R-S024R-N043R-R045T-S101A-N269R, G020R-S024R-N043R-R045T-S101A-T213A,, G020R-S024R-N043R-S242R, G020R-S024R-T38I-N043R-R045T-N076D-S242R-H249R, G020R-T022R-N043R, G020R-T022R-N043R-S212F, G020R-T022R-N043R-W241R, G020R-T038A-N043R-S101A, N018R-G020R-N043R, N018R-G020R-N043R-N076D, N018R-G020R-N043R-N076D-A230E-S242R, N018R-G020R-N043R-N076D-H249R, N018R-G020R-N043R-N076D-S242R-H249R, N018R-G020R-N043R-R045T-N076D-H249R, N018R-G020R-N043R-R045T-N076D-S101G-S103A-V104I-A232V-Q245R, N018R-G020R-N043R-R045T-S242R, N018R-G020R-S024R-N043R-N076D-H249R, N018R-G020R-S024R-N043R-R045T-N076D-A230E, N018R-G020R-S024R-N043R-R045T-N076D-H249R, P014L-G020R-S024R-N043R-R045T-S101A-A215F, S009A-G020R-N043R-S212F, S009A-G020R-N043R-W241R, S009A-G020R-S024R-N043R, V004R-G020R-N043R, V004R-G020R-S024R-N043R, V004R-G020R-S024R-N043R-S242R, V004R-S009A-G020R-N043R, and V004R-S009A-G020R-N043R-S242R, wherein the total net charge of the variant is 0, +1, +2, +3, +4, +5, -1, -2, -3, -4, or -5 relative to the total net charge of the Bacillus lentus subtilisin GG36 protease, and wherein the total net charge is obtained by one or more substitutions selected from: R45T, N62E, N76D, S101D, P129E, A158E, G159D, G159E, S166D, S188D, A230E, N18R, T22R, S24R, G118R, Q245R, H249R, N269R, E271F, and E271L, wherein the variant is a variant of a parent protease Bacillus lentus subtilisin GG36 protease comprising the amino acid sequence shown in SEQ ID NO:2, wherein said variant has at least 90% sequence identity to the amino acid sequence of SEQ ID NO:2, and wherein amino acid positions of the protease variant are numbered according to the numbering of corresponding amino acid positions in the amino acid sequence of Bacillus amyloliquefaciens subtilisin BPN' shown in SEQ ID NO:1.
A bag body comprising a bag material including a bottom portion and an opening portion, wherein a lifting rope is provided around the opening portion, a restraining rope that is pulled out through the opening portion is provided at the bottom portion, the bag material is filled with a filling material to form the bag body, the opening portion is closed after the bag material is filled with the filling material, and characterized in that, the bag body is within a predetermined range centered about a curve given by W/H1 (diameter/restraining rope length) = 15.898 × (W/W0)^2 - 17.784 × (W/W0) + 6.6314, where W represents a diameter of the bag body, H1 represents a length of the restraining rope from a bottom portion of the bag body to a root position of a mouth closing rope of the bag material through a center of the bag body, and W0 represents a diameter of the bag body when the bag body formed by filling the bag material with the filling material is most stable against waves. the bag material is filled with a filling material to form the bag body, the opening portion is closed after the bag material is filled with the filling material, and characterized in that, the bag body is within a predetermined range centered about a curve given by W/H1 (diameter/restraining rope length) = 15.898 × (W/W0)^2 - 17.784 × (W/W0) + 6.6314, where W represents a diameter of the bag body, H1 represents a length of the restraining rope from a bottom portion of the bag body to a root position of a mouth closing rope of the bag material through a center of the bag body, and W0 represents a diameter of the bag body when the bag body formed by filling the bag material with the filling material is most stable against waves.
Process for the preparation of complexes of 68 Ga by a complexing reaction between a chelator-functionalized molecule and 68 Ga is carried out in a buffered aqueous solution having a pH range of 3.0-4.5 characterized in that said complexing reaction is carried out in the presence of a compound capable of sequestering metal cations added at the beginning of the complexing reaction, said sequestering agent being chosen in the group consisting of: crown ethers, 1,10-phenantroline and 2,2'-Bipyridine.
A method implementable in a sensor, comprising: determining a respective position of the sensor among a series of sensors; and based on a result of the determining, performing either: a first procedure responsive to the result of the determining indicating the sensor being a first sensor in the series of sensors, or a second procedure responsive to the result of the determining indicating the sensor not being the first sensor in the series of sensors, wherein the first procedure comprises transmitting first data of sensed at least one parameter via a second input/output (I/O) pin of the sensor, and wherein the second procedure comprises either or both of: receiving second data from a preceding sensor in the series of sensors via a first I/O pin of the sensor; and transmitting the first data and the second data via the second I/O pin. determining a respective position of the sensor among a series of sensors; and based on a result of the determining, performing either: a first procedure responsive to the result of the determining indicating the sensor being a first sensor in the series of sensors, or a second procedure responsive to the result of the determining indicating the sensor not being the first sensor in the series of sensors, a first procedure responsive to the result of the determining indicating the sensor being a first sensor in the series of sensors, or a second procedure responsive to the result of the determining indicating the sensor not being the first sensor in the series of sensors, wherein the first procedure comprises transmitting first data of sensed at least one parameter via a second input/output (I/O) pin of the sensor, and wherein the second procedure comprises either or both of: receiving second data from a preceding sensor in the series of sensors via a first I/O pin of the sensor; and transmitting the first data and the second data via the second I/O pin. receiving second data from a preceding sensor in the series of sensors via a first I/O pin of the sensor; and transmitting the first data and the second data via the second I/O pin.
High-pressure device for applying expandable reaction mixtures comprising: - a mixing head (11, 38), - a distributor head (12, 37) lying fluidically downstream of the mixing head (11, 38), - at least three outlet lines attached to the distributor head (12, 37), - a feed line (8, 43) for a component A to the mixing head (11, 38), - a feed line (9, 44) for a component B to the mixing head (11, 38), - at least one feed line (5, 27-30) for an inert gas (1, 21) under increased pressure, the inert gas being compressed to a pressure of > 150 bar before introduction into component A or component B and being at a pressure that is higher than the pressure of the component into which it is introduced, - at least one static mixer (6, 31, 32), which is arranged fluidically upstream of the mixing head, for intimately mixing the inert gas under increased pressure and the respective component, - at least one measurement and control unit for setting the desired pressures of components A and B at the mixing head (11, 38). - a mixing head (11, 38), - a distributor head (12, 37) lying fluidically downstream of the mixing head (11, 38), - at least three outlet lines attached to the distributor head (12, 37), - a feed line (8, 43) for a component A to the mixing head (11, 38), - a feed line (9, 44) for a component B to the mixing head (11, 38), - at least one feed line (5, 27-30) for an inert gas (1, 21) under increased pressure, the inert gas being compressed to a pressure of > 150 bar before introduction into component A or component B and being at a pressure that is higher than the pressure of the component into which it is introduced, - at least one static mixer (6, 31, 32), which is arranged fluidically upstream of the mixing head, for intimately mixing the inert gas under increased pressure and the respective component, - at least one measurement and control unit for setting the desired pressures of components A and B at the mixing head (11, 38).