A system for adjusting tension in an artificial chordae tendineae, the system comprising: an anchor engageable with a papillary muscle or heart wall; a clip engageable with a leaflet of a heart valve; and an artificial chordae tendineae (200, 202, 302, 402, 502, 602, 702, 802, 902, 1002, 1102, 1202, 1302, 1402, 1502, 1602) coupleable between the clip and the anchor; wherein the anchor includes: a body portion (308, 508, 608, 701, 801, 901, 1204), and a locking portion (310, 410, 510, 610, 704, 800, 900, 1000, 1100, 1200, 1300, 1400, 1500, 1600) coupleable with the artificial chordae tendineae and configured to allow movement of the artificial chordae tendineae in a first direction while preventing movement of the artificial chordae tendineae in a second direction opposite the first direction; characterized by an actuator (328, 428, 520, 630, 808, 908, 1030, 1118, 1220, 1334, 1422) coupled to the locking portion, the actuator for selectively releasing the locking portion to enable selective movement of the artificial chordae tendineae in the second direction, wherein the actuator is couplable to a filament (328, 428) disposed in or on a catheter and wherein the actuator is configured such that a user can activate the actuator to release the locking portion by applying a force to the filament (328, 428). an anchor engageable with a papillary muscle or heart wall; a clip engageable with a leaflet of a heart valve; and an artificial chordae tendineae (200, 202, 302, 402, 502, 602, 702, 802, 902, 1002, 1102, 1202, 1302, 1402, 1502, 1602) coupleable between the clip and the anchor; wherein the anchor includes: a body portion (308, 508, 608, 701, 801, 901, 1204), and a locking portion (310, 410, 510, 610, 704, 800, 900, 1000, 1100, 1200, 1300, 1400, 1500, 1600) coupleable with the artificial chordae tendineae and configured to allow movement of the artificial chordae tendineae in a first direction while preventing movement of the artificial chordae tendineae in a second direction opposite the first direction; characterized by an actuator (328, 428, 520, 630, 808, 908, 1030, 1118, 1220, 1334, 1422) coupled to the locking portion, the actuator for selectively releasing the locking portion to enable selective movement of the artificial chordae tendineae in the second direction, wherein the actuator is couplable to a filament (328, 428) disposed in or on a catheter and wherein the actuator is configured such that a user can activate the actuator to release the locking portion by applying a force to the filament (328, 428). a body portion (308, 508, 608, 701, 801, 901, 1204), and a locking portion (310, 410, 510, 610, 704, 800, 900, 1000, 1100, 1200, 1300, 1400, 1500, 1600) coupleable with the artificial chordae tendineae and configured to allow movement of the artificial chordae tendineae in a first direction while preventing movement of the artificial chordae tendineae in a second direction opposite the first direction; characterized by an actuator (328, 428, 520, 630, 808, 908, 1030, 1118, 1220, 1334, 1422) coupled to the locking portion, the actuator for selectively releasing the locking portion to enable selective movement of the artificial chordae tendineae in the second direction, wherein the actuator is couplable to a filament (328, 428) disposed in or on a catheter and wherein the actuator is configured such that a user can activate the actuator to release the locking portion by applying a force to the filament (328, 428).