An ambulatory medical device capable of delivering therapy to a patient, the ambulatory medical device comprising: at least one response mechanism capable of being activated by a single response button; a controller operatively coupled with the at least one response mechanism, the controller including at least one processor coupled with a memory; and a therapy manager component executable by the controller and configured to: detect a physiological parameter indicative of a health disorder of the patient; request the patient to change the state of the at least one response mechanism in response to the detection of the physiological parameter; monitor the state of the at least one response mechanism within a first predetermined period; and delay administration of therapy to the patient in response to detection of a change in the state of the at least one response mechanism within the first predetermined period; monitor the state of the at least one response mechanism for a second predetermined period; request the patient change the state in response to detection of the state remaining unchanged during the second predetermined period; further delay the administration of therapy in response to detection of a change in the state during the second predetermined period; and prepare to deliver the therapy to the patient in response to the state remaining unchanged until expiration of the second predetermined period. at least one response mechanism capable of being activated by a single response button; a controller operatively coupled with the at least one response mechanism, the controller including at least one processor coupled with a memory; and a therapy manager component executable by the controller and configured to: detect a physiological parameter indicative of a health disorder of the patient; request the patient to change the state of the at least one response mechanism in response to the detection of the physiological parameter; monitor the state of the at least one response mechanism within a first predetermined period; and delay administration of therapy to the patient in response to detection of a change in the state of the at least one response mechanism within the first predetermined period; monitor the state of the at least one response mechanism for a second predetermined period; request the patient change the state in response to detection of the state remaining unchanged during the second predetermined period; further delay the administration of therapy in response to detection of a change in the state during the second predetermined period; and prepare to deliver the therapy to the patient in response to the state remaining unchanged until expiration of the second predetermined period. detect a physiological parameter indicative of a health disorder of the patient; request the patient to change the state of the at least one response mechanism in response to the detection of the physiological parameter; monitor the state of the at least one response mechanism within a first predetermined period; and delay administration of therapy to the patient in response to detection of a change in the state of the at least one response mechanism within the first predetermined period; monitor the state of the at least one response mechanism for a second predetermined period; request the patient change the state in response to detection of the state remaining unchanged during the second predetermined period; further delay the administration of therapy in response to detection of a change in the state during the second predetermined period; and prepare to deliver the therapy to the patient in response to the state remaining unchanged until expiration of the second predetermined period.