A receptacle for preparing tissue samples using fluorescent staining agent solution and/or rinsing solution, the receptacle comprising: a container having a proximal end and a distal end, the container comprising a container opening at the proximal end and a bottom at the distal end; and a removable basket that is positioned in the container, wherein the basket has a proximal end and a distal end and the basket comprises a permeable sample holding element (e.g., a mesh or porous element) disposed at the distal end, wherein the permeable sample holding element (i) comprises one or more side walls and a bottom, and a sample submersion retention element, the sample retention element disposed between the proximal end and the distal end of the basket, wherein the sample retention element is hinged or tensioned to the permeable sample holding element to provide an opening on the proximal side of the sample holding element or wherein the permeable sample holding element has a vertical opening on a side of the sample holding element, and (ii) is constructed to position a tissue sample in contact with a fluid disposed within the container at or near the distal end of the container when the basket is positioned in the container, wherein the container opening has an opening inner diameter of at least 5 mm and no more than 150 mm, wherein the container has a size and shape that defines a fillable volume, wherein the fillable volume is in a range from 5 mL to 750 mL. a container having a proximal end and a distal end, the container comprising a container opening at the proximal end and a bottom at the distal end; and a removable basket that is positioned in the container, wherein the basket has a proximal end and a distal end and the basket comprises a permeable sample holding element (e.g., a mesh or porous element) disposed at the distal end, wherein the permeable sample holding element (i) comprises one or more side walls and a bottom, and a sample submersion retention element, the sample retention element disposed between the proximal end and the distal end of the basket, wherein the sample retention element is hinged or tensioned to the permeable sample holding element to provide an opening on the proximal side of the sample holding element or wherein the permeable sample holding element has a vertical opening on a side of the sample holding element, and (ii) is constructed to position a tissue sample in contact with a fluid disposed within the container at or near the distal end of the container when the basket is positioned in the container, (i) comprises one or more side walls and a bottom, and a sample submersion retention element, the sample retention element disposed between the proximal end and the distal end of the basket, wherein the sample retention element is hinged or tensioned to the permeable sample holding element to provide an opening on the proximal side of the sample holding element or wherein the permeable sample holding element has a vertical opening on a side of the sample holding element, and (ii) is constructed to position a tissue sample in contact with a fluid disposed within the container at or near the distal end of the container when the basket is positioned in the container, wherein the container opening has an opening inner diameter of at least 5 mm and no more than 150 mm, wherein the container has a size and shape that defines a fillable volume, wherein the fillable volume is in a range from 5 mL to 750 mL.