mhurhangee/ep-ind-claims huggingface dataset:
A method for selecting an aptamer that binds a ligand in eukaryotic cells comprising the steps of: (a) providing a library of aptamers, (b) introducing the members of the library of aptamers into a polynucleotide cassette for the ligand-mediated expression of a reporter gene to create a library of riboswitches, (c) introducing the library of riboswitches into eukaryotic cells, and (d) contacting the eukaryotic cells with a ligand, and (e) measuring expression of the reporter gene, wherein the polynucleotide cassette comprises an alternatively-spliced exon, flanked by a 5' intron and a 3' intron, and a riboswitch comprising (i) an effector region comprising a stem that includes the 5' splice site sequence of the 3' intron and a sequence complementary to the 5' splice site sequence of the 3' intron, and (ii) an aptamer positioned between the 5' splice site sequence of the 3' intron and the complementary sequence, wherein the alternatively-spliced exon comprises a stop codon that is in-frame with the reporter gene when the alternatively-spliced exon is spliced into the reporter gene mRNA. (a) providing a library of aptamers, (b) introducing the members of the library of aptamers into a polynucleotide cassette for the ligand-mediated expression of a reporter gene to create a library of riboswitches, (c) introducing the library of riboswitches into eukaryotic cells, and (d) contacting the eukaryotic cells with a ligand, and (e) measuring expression of the reporter gene,
A vehicle sound absorption structure comprising: a recessed cell that has an opening on one end thereof; a divider that is provided within the cell and that divides an acoustic wave entering the cell from the opening into two acoustic waves (32, 34); reflectors (16, 18) that reflect one of the two acoustic waves divided at the divider and reflect the other acoustic wave respectively toward the opening, and that generate a phase difference between the one acoustic wave and the other acoustic wave; and an interfering portion that is provided within the cell and that causes the one acoustic wave and the other acoustic wave, which have been respectively reflected at the reflectors, to interfere with each other; characterized by: a cover member that covers the opening; wherein the cover member has a slit that is provided at a position where an imaginary line that extends from the divider toward the opening intersects the cover member; the divider has an end on the side of the opening and positioned more inward in the cell than the opening, while being positioned closer to the opening than one of the reflectors, the one of the reflectors being positioned closer to the opening than the other reflector; and the interfering portion is positioned between the end and the opening. a recessed cell that has an opening on one end thereof; a divider that is provided within the cell and that divides an acoustic wave entering the cell from the opening into two acoustic waves (32, 34); reflectors (16, 18) that reflect one of the two acoustic waves divided at the divider and reflect the other acoustic wave respectively toward the opening, and that generate a phase difference between the one acoustic wave and the other acoustic wave; and an interfering portion that is provided within the cell and that causes the one acoustic wave and the other acoustic wave, which have been respectively reflected at the reflectors, to interfere with each other; characterized by: a cover member that covers the opening; wherein the cover member has a slit that is provided at a position where an imaginary line that extends from the divider toward the opening intersects the cover member; the divider has an end on the side of the opening and positioned more inward in the cell than the opening, while being positioned closer to the opening than one of the reflectors, the one of the reflectors being positioned closer to the opening than the other reflector; and the interfering portion is positioned between the end and the opening. a cover member that covers the opening; wherein the cover member has a slit that is provided at a position where an imaginary line that extends from the divider toward the opening intersects the cover member; the divider has an end on the side of the opening and positioned more inward in the cell than the opening, while being positioned closer to the opening than one of the reflectors, the one of the reflectors being positioned closer to the opening than the other reflector; and the interfering portion is positioned between the end and the opening.
A clamp sprinkler bracket, which enables the fixation of the Sprinkler sleeve, which is the end part of the sprinkler hose in the sprinkler systems that are used as fire extinguishing systems, onto the profiles formed on the ceiling, comprising; • A bottom clamp which constitutes the general structure of the said clamp sprinkler bracket and which, when installed, is fixated by being connected to the profile, • A profile slot, into which the said profile is inserted in the said bottom clamp, • A top clamp, which is used as the corresponding part of the said bottom clamp and which also constitutes the general structure of the said clamp sprinkler bracket, • A sleeve slot, which is formed in the middle of the bottom clamp and the top clamp when they are superimposed to each other and into which, when installed, the Sprinkler sleeve is placed, • Clamp sleeve gaps, which are formed on the bottom clamp and the top clamp and which enable the said sleeve slot to be formed, • A fixation element which fixates the said bottom clamp and the said top clamp to each other and by this way enables the top clamp to use this fixation point as a joint and so that the top clamp can be opened and closed, • A locking shaft which enables the locking when the top clamp is rotated by using the said fixation element as a joint and is closed onto the bottom clamp, characterized in that it comprises • A holding arm which is the extension of the locking shaft towards the out of the bottom clamp and which enables to the locking step to be performed by the locking shaft is rotated on own axis. • A bottom clamp which constitutes the general structure of the said clamp sprinkler bracket and which, when installed, is fixated by being connected to the profile, • A profile slot, into which the said profile is inserted in the said bottom clamp, • A top clamp, which is used as the corresponding part of the said bottom clamp and which also constitutes the general structure of the said clamp sprinkler bracket, • A sleeve slot, which is formed in the middle of the bottom clamp and the top clamp when they are superimposed to each other and into which, when installed, the Sprinkler sleeve is placed, • Clamp sleeve gaps, which are formed on the bottom clamp and the top clamp and which enable the said sleeve slot to be formed, • A fixation element which fixates the said bottom clamp and the said top clamp to each other and by this way enables the top clamp to use this fixation point as a joint and so that the top clamp can be opened and closed, • A locking shaft which enables the locking when the top clamp is rotated by using the said fixation element as a joint and is closed onto the bottom clamp, characterized in that it comprises • A holding arm which is the extension of the locking shaft towards the out of the bottom clamp and which enables to the locking step to be performed by the locking shaft is rotated on own axis.
A hair dye composition comprising the following components, and and having pH (25°C) of 7.5 or more and 12 or less:: one or more azo dyes selected from the group consisting of the following (A-1), (A-2) and (A-3):: a cationic compound: 0.1 mass% or more and 8 mass% or less of at least one alkali metal salt of an acid selected from the group consisting of hydrochloric acid and sulfuric acid.: one or more azo dyes selected from the group consisting of the following (A-1), (A-2) and (A-3):: a cationic compound: 0.1 mass% or more and 8 mass% or less of at least one alkali metal salt of an acid selected from the group consisting of hydrochloric acid and sulfuric acid.
A process for preparing glycocholic acid of formula, or a salt thereof, comprising: - reacting cholic acid of formula with pivaloyl chloride in the presence of a base to give an activated intermediate of formula - reacting the obtained activated intermediate of formula with glycine or with an ester or a salt thereof; - in case of reacting with a glycine ester, hydrolyzing subsequently the ester; - isolating glycocholic acid of formula and optionally salification thereof. - reacting cholic acid of formula with pivaloyl chloride in the presence of a base to give an activated intermediate of formula - reacting the obtained activated intermediate of formula with glycine or with an ester or a salt thereof; - in case of reacting with a glycine ester, hydrolyzing subsequently the ester; - isolating glycocholic acid of formula and optionally salification thereof.
Method for mounting rotor blades on a rotor disk along a predetermined pitch circle diameter in such a way that shrouds of adjacent rotor blades mounted on the rotor disk in the intended manner and in the cold state are clamped against each other with a predetermined pretension, wherein the method features the consecutive steps: a) mounting each rotor blade on an associated clamping element of a clamping device in such a way that the rotor blades are arranged along a first pitch circle diameter (D 1) which is larger than the predetermined pitch circle diameter, wherein the shrouds of the rotor blades which are retained on the clamping elements are not clamped against each other or with a pretension which is lower than the predetermined pretension, b) moving the clamping elements radially inward until the rotor blades are arranged along a second pitch circle diameter (D 2) which corresponds to the predetermined pitch circle diameter, wherein the shrouds of the rotor blades are clamped against each other during the radial inward movement of the clamping elements until achieving the predetermined pretension, and c) mounting the rotor blades on the rotor disk in that state in which the shrouds of the rotor blades are clamped against each other with the predetermined pretension. a) mounting each rotor blade on an associated clamping element of a clamping device in such a way that the rotor blades are arranged along a first pitch circle diameter (D 1) which is larger than the predetermined pitch circle diameter, wherein the shrouds of the rotor blades which are retained on the clamping elements are not clamped against each other or with a pretension which is lower than the predetermined pretension, b) moving the clamping elements radially inward until the rotor blades are arranged along a second pitch circle diameter (D 2) which corresponds to the predetermined pitch circle diameter, wherein the shrouds of the rotor blades are clamped against each other during the radial inward movement of the clamping elements until achieving the predetermined pretension, and c) mounting the rotor blades on the rotor disk in that state in which the shrouds of the rotor blades are clamped against each other with the predetermined pretension.
Method for monitoring the operation of a magnetic piston pump, in which a piston executes an electromagnetically driven stroke movement with a movement start and a movement end, the stroke movement being caused by a magnet armature arranged on the piston by means of an electromagnetic field, which is generated by energisation of at least one coil with a coil current, the energisation having a switch-on timepoint and a switch-off timepoint, characterised in that the movement start (ta) and/or the movement end (teA, teB, teC) of the stroke movement is determined by means of the steps: - measurement and detection of the actual coil current; - calculation and detection of a difference (la; le) between a stored coil current and the actual coil current starting with the switch-on timepoint of the energisation over a defined period of time; - evaluation of this difference for determination of the movement start (ta) and/or the movement end (teA, teB, teC) of the electromagnetically driven stroke movement. - measurement and detection of the actual coil current; - calculation and detection of a difference (la; le) between a stored coil current and the actual coil current starting with the switch-on timepoint of the energisation over a defined period of time; - evaluation of this difference for determination of the movement start (ta) and/or the movement end (teA, teB, teC) of the electromagnetically driven stroke movement.
A method performed by a control plane of a central unit, CU-C,, comprising: transmitting a first message to a user plane of the central unit, CU-U, requesting to either establish or modify a context of a data radio bearer, DRB; and receiving a second message from the CU-U indicating that the context of the DRB has been established or modified at the CU-U, wherein the first message comprises first user plane address information of the DRB which comprises a S1 Uplink, UL, General Packet Radio Service Tunneling Protocol, GTP, Tunnel Endpoint Identifier, TEID, or a NG UL GTP TEID, and the second message comprises second user plane address information of the DRB which comprises: a F1 UL GTP TEID at the CU-U, and a S 1 Downlink, DL, GTP TEID or a NG DL GTP TEID at the CU-U. transmitting a first message to a user plane of the central unit, CU-U, requesting to either establish or modify a context of a data radio bearer, DRB; and receiving a second message from the CU-U indicating that the context of the DRB has been established or modified at the CU-U, wherein the first message comprises first user plane address information of the DRB which comprises a S1 Uplink, UL, General Packet Radio Service Tunneling Protocol, GTP, Tunnel Endpoint Identifier, TEID, or a NG UL GTP TEID, and the second message comprises second user plane address information of the DRB which comprises: a F1 UL GTP TEID at the CU-U, and a S 1 Downlink, DL, GTP TEID or a NG DL GTP TEID at the CU-U.
A nucleic acid molecule comprising a polynucleotide encoding an RNA-guided nuclease polypeptide, wherein said polynucleotide comprises a nucleotide sequence encoding an RGN polypeptide comprising an amino acid sequence having at least 90% sequence identity to SEQ ID NO: 83; wherein said RGN polypeptide is capable of binding a target DNA sequence in an RNA-guided sequence specific manner when bound to a guide RNA (gRNA) capable of hybridizing to said target DNA sequence, and wherein said RGN polypeptide recognizes a protospacer adjacent motif sequence comprising the consensus sequence of SEQ ID NO: 82. wherein said RGN polypeptide is capable of binding a target DNA sequence in an RNA-guided sequence specific manner when bound to a guide RNA (gRNA) capable of hybridizing to said target DNA sequence, and wherein said RGN polypeptide recognizes a protospacer adjacent motif sequence comprising the consensus sequence of SEQ ID NO: 82.
A device for filling a container with a filling product, comprising a filling valve for influencing the supply of the filling product into the container to be filled, preferably during the transport, by means of a container transporting device, of the container to be filled, a dosing valve for dosing a dosing product from a dosing product reservoir (4, 5) into the filling valve, a main component reservoir for providing a main component at the filling valve, a dosing product changing device for changing the dosing product in the dosing product reservoir (4, 5) during the filling operation, and a pressurization gas valve configured to control or regulate the pressure in the dosing product reservoir (4, 5), wherein the dosing product changing device is configured to switch the pressurization gas valve so that the pressure for forcing the dosing product back into the dosing product reservoir (4, 5) is lowered.
A video encoding apparatus for encoding a video having a plurality of color components, the video encoding apparatus comprising: linear prediction means comprising coefficient deriving means for deriving a prediction coefficient based on first reference pixels of a first color component of the plurality of color components and second reference pixels of a second color component other than the first color component among the plurality of color components, and inter-channel reference pixel generation means for generating third reference pixels of the second color component; and intra prediction means for performing intra prediction of a prediction target block of the second color component using the third reference pixels; characterized in that said inter-channel reference pixel generation means generate said third reference pixels of the second color component based on the prediction coefficient and the first reference pixels. linear prediction means comprising coefficient deriving means for deriving a prediction coefficient based on first reference pixels of a first color component of the plurality of color components and second reference pixels of a second color component other than the first color component among the plurality of color components, and inter-channel reference pixel generation means for generating third reference pixels of the second color component; and intra prediction means for performing intra prediction of a prediction target block of the second color component using the third reference pixels; characterized in that said inter-channel reference pixel generation means generate said third reference pixels of the second color component based on the prediction coefficient and the first reference pixels.
An ink jet print head subassembly, comprising: a separator layer including one or more separator elements configured to separate bubbles of a vapor from ink; an inlet layer including one or more inlets configured to allow passage of the ink that includes the bubbles of the vapor into the separator element; and an outlet layer including at least one vapor outlet configured to allow the vapor that has been separated from the ink to exit from the separator element, and one or more ink outlets configured to allow the ink to exit from the separator element; the separator layer being dispensed between the inlet layer and the outlet layer, and the separator element including a centre portion forming a vapor region configured to allow movement of the vapor within the separator element, characterised in that each separator element comprises wicking features having dimensions sufficient to allow capillary movement of the ink in the wicking features and to substantially exclude the bubbles of the vapor from the wickeing features, such that the ink moves primarily in the wicking features of the separator element to the ink outlets and the vapor moves primarily in the vapor region to the vapor outlet. a separator layer including one or more separator elements configured to separate bubbles of a vapor from ink; an inlet layer including one or more inlets configured to allow passage of the ink that includes the bubbles of the vapor into the separator element; and an outlet layer including at least one vapor outlet configured to allow the vapor that has been separated from the ink to exit from the separator element, and one or more ink outlets configured to allow the ink to exit from the separator element; the separator layer being dispensed between the inlet layer and the outlet layer, and the separator element including a centre portion forming a vapor region configured to allow movement of the vapor within the separator element, characterised in that each separator element comprises wicking features having dimensions sufficient to allow capillary movement of the ink in the wicking features and to substantially exclude the bubbles of the vapor from the wickeing features, such that the ink moves primarily in the wicking features of the separator element to the ink outlets and the vapor moves primarily in the vapor region to the vapor outlet.
A method of securely caching data stored in an electronic identity document, the method comprising: reading biometric data from said electronic document, using all or part of said biometric data to calculate a unique cryptographic key for said data; encrypting all or part of said biometric data with said unique cryptographic key; discarding said unique cryptographic key after encryption and caching said encrypted biometric data in a data cache, with decryption of encrypted data requiring the presence of said electronic identity document to recalculate said unique cryptographic key from said electronic identity document. reading biometric data from said electronic document, using all or part of said biometric data to calculate a unique cryptographic key for said data; encrypting all or part of said biometric data with said unique cryptographic key; discarding said unique cryptographic key after encryption and caching said encrypted biometric data in a data cache, with decryption of encrypted data requiring the presence of said electronic identity document to recalculate said unique cryptographic key from said electronic identity document.
Beverage preparation device for preparing a beverage from a beverage dose comprising: - a brewing unit for receiving the dose and preparing a beverage from the ingredients contained within the dose and pressurized liquid injected in the dose, - a pressure pump for supplying pressurized liquid to the brewing unit, - beverage dispensing means connected to the brewing unit and comprising a beverage injector arranged for dispensing the beverage through a bottom of a beverage receptacle;wherein the beverage dispensing means comprises a residual beverage draining valve, between the beverage injector and the brewing unit, which is arranged to be moved between a beverage dispensing position and a beverage residual draining position, characterized in that the residual beverage draining valve and/or the beverage receptacle comprise valve activation means arranged to move the draining valve between a beverage dispensing position in response to the engagement of the bottom of the receptacle with the beverage injector and a beverage residual draining position in response to the removal of receptacle from the beverage injector. - a brewing unit for receiving the dose and preparing a beverage from the ingredients contained within the dose and pressurized liquid injected in the dose, - a pressure pump for supplying pressurized liquid to the brewing unit, - beverage dispensing means connected to the brewing unit and comprising a beverage injector arranged for dispensing the beverage through a bottom of a beverage receptacle;wherein the beverage dispensing means comprises a residual beverage draining valve, between the beverage injector and the brewing unit, which is arranged to be moved between a beverage dispensing position and a beverage residual draining position, characterized in that the residual beverage draining valve and/or the beverage receptacle comprise valve activation means arranged to move the draining valve between a beverage dispensing position in response to the engagement of the bottom of the receptacle with the beverage injector and a beverage residual draining position in response to the removal of receptacle from the beverage injector.