A patch (210; 225; 290; 301; 306; 311; 316; 322; 328; 801; 807; 813; 819; 825; 1201; 1227; 1251;) for monitoring one or more physiologic, physical, and/or electrophysiological signals from a subject, comprising: a substrate (245; 1005; 1030; 1065;1203; 1230; 1253;) comprising a flexible, stretchable material; an adhesive (250; 1035; 1060;1205; 1235) coupled to the substrate formulated for attachment to the skin of the subject; one or more patch interconnects (219a-g; 230a,b; 287; 331a-c; 1040; 1070; 1211a,b; 1271a-c) embedded into the substrate for attachment of the patch to a module (215; 235; 260; 292; 305; 310; 315; 320;803; 809; 815; 821; 827; 1215; 1225; 1265) comprising one or more microcircuits (270; 1270); and at least one of one or more sensors and one or more electrodes (218a-d; 255a,b; 303a-e; 307a,b; 313a-f; 318a-c; 333a.b; 805a,b; 811a,b; 817a-c; 823a-d; 929a,b; 1050; 1070; 1207; 1208a,b; 1255a-c) attached to or embedded onto the surface of the substrate, the one or more sensors and/or one or more electrodes arranged, configured, and dimensioned to interface with the subject when the adhesive is attached thereto; wherein said at least one of the one or more sensors and the one or more electrodes are configured to monitor one or more physiologic signals, physical signals, and electrophysiological signals from the subject; wherein the one or more patch interconnects comprise one or more ferromagnetic regions (1211a,b) formed from a stretchable pseudo elastic material, the one or more ferromagnetic regions being printed onto the substrate; wherein the one or more patch interconnects are configured for mating with one or more magnetic elements of the module to attach the patch to the module; wherein the one or more patch interconnects provide an electrically conducting interface between the patch and the one or more microcircuits of the module. a substrate (245; 1005; 1030; 1065;1203; 1230; 1253;) comprising a flexible, stretchable material; an adhesive (250; 1035; 1060;1205; 1235) coupled to the substrate formulated for attachment to the skin of the subject; one or more patch interconnects (219a-g; 230a,b; 287; 331a-c; 1040; 1070; 1211a,b; 1271a-c) embedded into the substrate for attachment of the patch to a module (215; 235; 260; 292; 305; 310; 315; 320;803; 809; 815; 821; 827; 1215; 1225; 1265) comprising one or more microcircuits (270; 1270); and at least one of one or more sensors and one or more electrodes (218a-d; 255a,b; 303a-e; 307a,b; 313a-f; 318a-c; 333a.b; 805a,b; 811a,b; 817a-c; 823a-d; 929a,b; 1050; 1070; 1207; 1208a,b; 1255a-c) attached to or embedded onto the surface of the substrate, the one or more sensors and/or one or more electrodes arranged, configured, and dimensioned to interface with the subject when the adhesive is attached thereto; wherein said at least one of the one or more sensors and the one or more electrodes are configured to monitor one or more physiologic signals, physical signals, and electrophysiological signals from the subject; wherein the one or more patch interconnects comprise one or more ferromagnetic regions (1211a,b) formed from a stretchable pseudo elastic material, the one or more ferromagnetic regions being printed onto the substrate; wherein the one or more patch interconnects are configured for mating with one or more magnetic elements of the module to attach the patch to the module; wherein the one or more patch interconnects provide an electrically conducting interface between the patch and the one or more microcircuits of the module.