A pneumatic control valve manifold assembly comprising: a plurality of modular manifold segments (26a, 26b, 26c) arranged to provide different combinations of valve operations, each modular manifold segment (26a, 26b, 26c) including a modular manifold segment outer perimeter, a modular manifold segment mating face, and a modular manifold segment back-side face; a first valve receiving bore and a second valve receiving bore each extending inwardly into the modular manifold segment (26a, 26b, 26c) from said modular manifold segment outer perimeter; an inlet cavity and an exhaust cavity each extending through said modular manifold segment (26a, 26b, 26c) and passing between said first and second valve receiving bores (76, 78) such that said inlet and exhaust cavities (48, 50) are open at said modular manifold segment mating face and said modular manifold segment back-side face; a plurality of fluid passageways open to said modular manifold segment mating face that are arranged in fluid communication with said first and second valve receiving bores (76, 78); the plurality of manifold segments (26a, 26b, 26c) comprising a plurality of different configurations for said plurality of fluid passageways; said plurality of fluid passageways of a given modular manifold segment (26a, 26b, 26c) following one of said plurality of configurations that provide different combinations of valve operations; each modular manifold segment mating face including an abutment surface surrounding said plurality of fluid passageways, said abutment surface having a plurality of shapes depending upon said configuration of said plurality of fluid passageways; and said modular manifold segment back-side face including a plurality of sealing ribs arranged in a pattern that universally mates with each of said plurality of shapes of said abutment surface such that modular manifold segments (26a, 26b, 26c) with fluid passageways of different configurations can be stacked next to each other in a fluid-tight arrangement. a plurality of modular manifold segments (26a, 26b, 26c) arranged to provide different combinations of valve operations, each modular manifold segment (26a, 26b, 26c) including a modular manifold segment outer perimeter, a modular manifold segment mating face, and a modular manifold segment back-side face; a first valve receiving bore and a second valve receiving bore each extending inwardly into the modular manifold segment (26a, 26b, 26c) from said modular manifold segment outer perimeter; an inlet cavity and an exhaust cavity each extending through said modular manifold segment (26a, 26b, 26c) and passing between said first and second valve receiving bores (76, 78) such that said inlet and exhaust cavities (48, 50) are open at said modular manifold segment mating face and said modular manifold segment back-side face; a plurality of fluid passageways open to said modular manifold segment mating face that are arranged in fluid communication with said first and second valve receiving bores (76, 78); the plurality of manifold segments (26a, 26b, 26c) comprising a plurality of different configurations for said plurality of fluid passageways; said plurality of fluid passageways of a given modular manifold segment (26a, 26b, 26c) following one of said plurality of configurations that provide different combinations of valve operations; each modular manifold segment mating face including an abutment surface surrounding said plurality of fluid passageways, said abutment surface having a plurality of shapes depending upon said configuration of said plurality of fluid passageways; and said modular manifold segment back-side face including a plurality of sealing ribs arranged in a pattern that universally mates with each of said plurality of shapes of said abutment surface such that modular manifold segments (26a, 26b, 26c) with fluid passageways of different configurations can be stacked next to each other in a fluid-tight arrangement.