A method comprising: providing a drill-in treatment fluid that comprises an aqueous-based fluid, wherein the aqueous-based fluid of the drill-in treatment fluid is a first aqueous-based fluid, and a hydrophobically-modified cationic polymer, wherein the hydrophobically-modified cationic polymer of the drill-in treatment fluid is a first hydrophobically-modified cationic polymer, wherein the first hydrophobically-modified cationic polymer comprises at least one selected from the group consisting of polydialkyldiallyl polymers, a quaternary ammonium salt of polyethyleneimine polymers, a quaternary ammonium salt of polydimethylaminoethyl-methacrylate copolymers, a quaternary ammonium salt of polyN-(3-dimethylaminopropyl)acrylamide polymers, poly(dimethyldiallylammonium chloride), cationic co-polymers of poly(acrylamide), cationic poly(diemethylaminoethylmethacrylate), and any combination thereof, and wherein the hydrophobic modification comprises a Cs-C 18 hydrocarbon comprising an aromatic group; introducing the drill-in treatment fluid into at least a portion of a subterranean formation comprising water-sensitive minerals; allowing the first hydrophobically-modified cationic polymer to at least partially coat the water-sensitive mineral; then introducing a fracturing treatment fluid into at least the portion of the subterranean formation comprising water-sensitive minerals having been treated with the first hydrophobically-modified cationic polymer at a pressure sufficient to create or extend at least one fracture in the subterranean formation, the fracturing fluid comprising a second aqueous-based fluid, and a second hydrophobically-modified cationic polymer, wherein the second hydrophobically-modified cationic polymer comprises at least one selected from the group consisting of polydialkyldiallyl polymers, a quaternary ammonium salt of polyethyleneimine polymers, a quaternary ammonium salt of polydimethylaminoethyl-methacrylate copolymers, a quaternary ammonium salt of polyN-(3-dimethylaminopropyl)acrylamide polymers, poly(dimethyldiallylammonium chloride), cationic co-polymers of poly(acrylamide), cationic poly(diemethylaminoethylmethacrylate), and any combination thereof, and wherein the hydrophobic modification comprises a Cs-C 18 hydrocarbon comprising an aromatic group; and allowing the second hydrophobically-modified cationic polymer to at least partially coat the water-sensitive mineral. providing a drill-in treatment fluid that comprises an aqueous-based fluid, wherein the aqueous-based fluid of the drill-in treatment fluid is a first aqueous-based fluid, and a hydrophobically-modified cationic polymer, wherein the hydrophobically-modified cationic polymer of the drill-in treatment fluid is a first hydrophobically-modified cationic polymer, wherein the first hydrophobically-modified cationic polymer comprises at least one selected from the group consisting of polydialkyldiallyl polymers, a quaternary ammonium salt of polyethyleneimine polymers, a quaternary ammonium salt of polydimethylaminoethyl-methacrylate copolymers, a quaternary ammonium salt of polyN-(3-dimethylaminopropyl)acrylamide polymers, poly(dimethyldiallylammonium chloride), cationic co-polymers of poly(acrylamide), cationic poly(diemethylaminoethylmethacrylate), and any combination thereof, and wherein the hydrophobic modification comprises a Cs-C 18 hydrocarbon comprising an aromatic group; introducing the drill-in treatment fluid into at least a portion of a subterranean formation comprising water-sensitive minerals; allowing the first hydrophobically-modified cationic polymer to at least partially coat the water-sensitive mineral; then introducing a fracturing treatment fluid into at least the portion of the subterranean formation comprising water-sensitive minerals having been treated with the first hydrophobically-modified cationic polymer at a pressure sufficient to create or extend at least one fracture in the subterranean formation, the fracturing fluid comprising a second aqueous-based fluid, and a second hydrophobically-modified cationic polymer, wherein the second hydrophobically-modified cationic polymer comprises at least one selected from the group consisting of polydialkyldiallyl polymers, a quaternary ammonium salt of polyethyleneimine polymers, a quaternary ammonium salt of polydimethylaminoethyl-methacrylate copolymers, a quaternary ammonium salt of polyN-(3-dimethylaminopropyl)acrylamide polymers, poly(dimethyldiallylammonium chloride), cationic co-polymers of poly(acrylamide), cationic poly(diemethylaminoethylmethacrylate), and any combination thereof, and wherein the hydrophobic modification comprises a Cs-C 18 hydrocarbon comprising an aromatic group; and allowing the second hydrophobically-modified cationic polymer to at least partially coat the water-sensitive mineral.