mhurhangee/ep-ind-claims huggingface dataset:
A synthetic nucleic acid molecule encoding a synthetic mini-dystrophin gene or micro-dystrophin gene encoding a synthetic, non-full length dystrophin protein comprising: (i) an N-terminal domain of the dystrophin protein which includes amino acid residues 1 to 252 of SEQ ID NO: 1 of the dystrophin protein, or a variant thereof that exhibits at least 90% identity to residues 1 to 252 of SEQ ID NO: 1 and that retains substantial dystrophin function; and (ii) at least two membrane binding motifs independently selected from the group consisting of: (a) an MBM of an R1-R2 membrane binding domain comprising a cysteine residue corresponding to the conserved cysteine residue of the S-palmitoylation site peptide of SEQ ID NO: 54 or comprising an S-palmitoylation site peptide of SEQ ID NO: 54, (b) an MBM of an R11-R12 MBD comprising a cysteine residue corresponding to the conserved cysteine residue of the S-palmitoylation site peptide of SEQ ID NO: 57, (c) an MBM of a CR membrane binding domain, and (d) an MBM of a CT membrane binding domain; wherein the domains and the MBM are arranged from N to C terminus in the order in which they occur in a wild-type dystrophin protein and are operably linked. (i) an N-terminal domain of the dystrophin protein which includes amino acid residues 1 to 252 of SEQ ID NO: 1 of the dystrophin protein, or a variant thereof that exhibits at least 90% identity to residues 1 to 252 of SEQ ID NO: 1 and that retains substantial dystrophin function; and (ii) at least two membrane binding motifs independently selected from the group consisting of: (a) an MBM of an R1-R2 membrane binding domain comprising a cysteine residue corresponding to the conserved cysteine residue of the S-palmitoylation site peptide of SEQ ID NO: 54 or comprising an S-palmitoylation site peptide of SEQ ID NO: 54, (b) an MBM of an R11-R12 MBD comprising a cysteine residue corresponding to the conserved cysteine residue of the S-palmitoylation site peptide of SEQ ID NO: 57, (c) an MBM of a CR membrane binding domain, and (d) an MBM of a CT membrane binding domain; (a) an MBM of an R1-R2 membrane binding domain comprising a cysteine residue corresponding to the conserved cysteine residue of the S-palmitoylation site peptide of SEQ ID NO: 54 or comprising an S-palmitoylation site peptide of SEQ ID NO: 54, (b) an MBM of an R11-R12 MBD comprising a cysteine residue corresponding to the conserved cysteine residue of the S-palmitoylation site peptide of SEQ ID NO: 57, (c) an MBM of a CR membrane binding domain, and (d) an MBM of a CT membrane binding domain;
A rack and pinion linear transmission arrangement comprising a rack, a pinion, and a gearbox, said gearbox including - a reduction gear train having at least a first, a second, a third, and a fourth gear wheel, where the fourth gear wheel is arranged to be operable as the pinion for rotary engagement with the rack; - a rotary input shaft operatively connected to the gear train and arranged to effect a linear movement of the gearbox up and down the rack; and - an intermediate shaft on which the first and the second gear wheels are fixed; and wherein - the third gear wheel is fixed on the input shaft, and the fourth gear wheel is journaled on the input shaft to enable the fourth gear wheel to rotate freely relative to the input shaft, wherein the first gear wheel and the fourth gear wheel are in constant meshing engagement with each other. - a reduction gear train having at least a first, a second, a third, and a fourth gear wheel, where the fourth gear wheel is arranged to be operable as the pinion for rotary engagement with the rack; - a rotary input shaft operatively connected to the gear train and arranged to effect a linear movement of the gearbox up and down the rack; and - an intermediate shaft on which the first and the second gear wheels are fixed; and wherein - the third gear wheel is fixed on the input shaft, and the fourth gear wheel is journaled on the input shaft to enable the fourth gear wheel to rotate freely relative to the input shaft, wherein the first gear wheel and the fourth gear wheel are in constant meshing engagement with each other.
Refractory sintered product, in the form of a block, including more than 99%, by weight, of oxides and having the following average chemical composition, the percentages by weight being on the basis of the oxides: 20% < Al 2 O 3 < 90% 2% ≤ SiO 2 < 30% 3% < ZrO 2 < 50% 0% ≤ Cr 2 O 3 < 0.5% this product containing 17 to 85% of mullite-zirconia grains, containing at least 1% of mullite-zirconia grains having a size of 0.3 mm or less, and containing, as percentages by weight on the basis of the oxides, less than 22% of mullite-zirconia grains having a size of 0.7 mm or less. 20% < Al 2 O 3 < 90% 2% ≤ SiO 2 < 30% 3% < ZrO 2 < 50% 0% ≤ Cr 2 O 3 < 0.5%
An ultrasound transducer, comprising: a control circuit which comprises an integrated circuit, the integrated circuit comprising an array of circuit portions; an array of capacitive micromachined ultrasound transducer, cMUT, elements provided to overlay the control circuit; and an array of vias, with at least one via providing a coupling between each cMUT element and a respective one of the circuit portions said CMUT element is arranged to overlay, those circuit portions together defining a circuit area, characterized in that the pitch of the array of cMUT elements is greater than the pitch of the circuit portions in at least one direction of the array such that in said at least one direction, the cMUT elements extend beyond one or both sides of the circuit area in said at least one direction, wherein the at least one direction of the array comprises a row direction or both row and column directions. a control circuit which comprises an integrated circuit, the integrated circuit comprising an array of circuit portions; an array of capacitive micromachined ultrasound transducer, cMUT, elements provided to overlay the control circuit; and an array of vias, with at least one via providing a coupling between each cMUT element and a respective one of the circuit portions said CMUT element is arranged to overlay, those circuit portions together defining a circuit area, characterized in that the pitch of the array of cMUT elements is greater than the pitch of the circuit portions in at least one direction of the array such that in said at least one direction, the cMUT elements extend beyond one or both sides of the circuit area in said at least one direction, wherein the at least one direction of the array comprises a row direction or both row and column directions.
A non-aqueous patch comprising 0.5 to 7 mass% lidocaine, and a dissolving agent composed of isostearic acid and a polyalcohol wherein the lidocaine and the dissolving agent are contained in a base of plaster, the plaster being held by a support, wherein the support has a stretch strength of less than 2,000g/50mm when the support is stretched to 50% longitudinal extension; and wherein the support is a biaxially-oriented stretch cloth.
A cladding panel for a wall comprising: - an outer layer having a rear face and including a plurality of plates; - an inner layer having a front face, assembled to the rear face of the outer layer and binding the plates, and a rear face configured to be disposed against the wall; - first and second borders (18, 20) extending substantially parallel to each other; - a third border extending transversely relative to the first border; characterized in that it further includes at least: - a first fixing device extending along the first border and having: ∘ a mounting portion embedded in the inner layer; ∘ a fixing portion extending from the inner layer and configured to cooperate with a fixing means for fixing the panel to said wall; ∘ an assembly portion configured to assemble said panel with a second panel; and - a second fixing device extending along the third border. - an outer layer having a rear face and including a plurality of plates; - an inner layer having a front face, assembled to the rear face of the outer layer and binding the plates, and a rear face configured to be disposed against the wall; - first and second borders (18, 20) extending substantially parallel to each other; - a third border extending transversely relative to the first border; - a first fixing device extending along the first border and having: ∘ a mounting portion embedded in the inner layer; ∘ a fixing portion extending from the inner layer and configured to cooperate with a fixing means for fixing the panel to said wall; ∘ an assembly portion configured to assemble said panel with a second panel; and ∘ a mounting portion embedded in the inner layer; ∘ a fixing portion extending from the inner layer and configured to cooperate with a fixing means for fixing the panel to said wall; ∘ an assembly portion configured to assemble said panel with a second panel; and - a second fixing device extending along the third border.
A method for receiving control information of a terminal in a mobile communication system, the method comprising: receiving, by the terminal, the control information including antenna port related information which is associated with a demodulation reference signal, DM-RS; identifying whether a transport block 0 is enabled and a transport block 1 is disabled, or both the transport block 0 and the transport block 1 are enabled based on the control information; and identifying a number of at least one antenna port of the DM-RS and a number of at least one layer based on the antenna port related information according to a result of the identification, wherein the antenna port related information is capable of indicating up to 8 layers in a case that the transport block 1 and the transport block 2 are enabled and 4 layers in a case that the transport block 0 is enabled and transport block 1 is disabled. receiving, by the terminal, the control information including antenna port related information which is associated with a demodulation reference signal, DM-RS; identifying whether a transport block 0 is enabled and a transport block 1 is disabled, or both the transport block 0 and the transport block 1 are enabled based on the control information; and identifying a number of at least one antenna port of the DM-RS and a number of at least one layer based on the antenna port related information according to a result of the identification, wherein the antenna port related information is capable of indicating up to 8 layers in a case that the transport block 1 and the transport block 2 are enabled and 4 layers in a case that the transport block 0 is enabled and transport block 1 is disabled.
A method in a requesting network node in a communication network implementing a link state protocol for determining whether a requested network configuration has been implemented, the method comprising: sending, by the requesting network node, a configuration descriptor within a first link state message by flooding the first link state message to one or more peer network nodes in the communication network, wherein the configuration descriptor describes the requested network configuration; receiving, by the requesting network node, one or more result reports within one or more link state messages originated by the one or more peer network nodes and flooded through the communication network, wherein each of the one or more result reports indicates a result of an attempt by the respective originating peer network node to perform a configuration action taken responsive to the configuration descriptor; and determining, by the requesting network node, whether the requested network configuration has been implemented based upon the one or more result reports. sending, by the requesting network node, a configuration descriptor within a first link state message by flooding the first link state message to one or more peer network nodes in the communication network, wherein the configuration descriptor describes the requested network configuration; receiving, by the requesting network node, one or more result reports within one or more link state messages originated by the one or more peer network nodes and flooded through the communication network, wherein each of the one or more result reports indicates a result of an attempt by the respective originating peer network node to perform a configuration action taken responsive to the configuration descriptor; and determining, by the requesting network node, whether the requested network configuration has been implemented based upon the one or more result reports.
A method comprising: receiving a set of focal stack images; for at least one focal stack image, grouping each of a plurality of pixels of each respective at least one focal stack image into a plurality of super pixels; calculating a focal measure for each of a plurality of the super pixels using a Laplacian filter; segmenting a respective focal stack image based on the focal measures of the plurality of super pixels; classifying the plurality of super pixels as foreground or background based on the segmentation of the respective focal stack image; calculating a color probability for respective super pixels using classification of super pixels as foreground or background; and segmenting the respective focal stack image based on the color probability of respective super pixels. receiving a set of focal stack images; for at least one focal stack image, grouping each of a plurality of pixels of each respective at least one focal stack image into a plurality of super pixels; calculating a focal measure for each of a plurality of the super pixels using a Laplacian filter; segmenting a respective focal stack image based on the focal measures of the plurality of super pixels; classifying the plurality of super pixels as foreground or background based on the segmentation of the respective focal stack image; calculating a color probability for respective super pixels using classification of super pixels as foreground or background; and segmenting the respective focal stack image based on the color probability of respective super pixels.
Container of single-dose cosmetic products comprising - an external vessel formed by: a hollow body and a closure element adapted to isolate an internal cavity of said hollow body, - a plurality of single-dose containers (8, 8A, 80) containing a cosmetic product, housed in the cavity of the hollow body, each single-dose container (8, 8A, 80) being separately sealed, characterized in that - the external vessel has a housing adapted to constrain, in a use position, at least one single-dose container (8A, 80); - and that said housing is provided at a portion of the external surface of said vessel. - an external vessel formed by: a hollow body and a closure element adapted to isolate an internal cavity of said hollow body, - a plurality of single-dose containers (8, 8A, 80) containing a cosmetic product, housed in the cavity of the hollow body, each single-dose container (8, 8A, 80) being separately sealed, - the external vessel has a housing adapted to constrain, in a use position, at least one single-dose container (8A, 80); - and that said housing is provided at a portion of the external surface of said vessel.
An aerosol provision device comprising: a housing delimiting an opening at one end, the opening being configured to receive aerosol generating material therein; a lid moveable from an open position where the opening is exposed, to a closed position where the opening is covered, via an intermediate position; and a spring, characterised in that: a first end of the spring is connected to the lid at a first pivot point and the first end is rotatable about the first pivot point as the lid moves between the open and closed positions; a second end of the spring is connected to the housing at a second pivot point and the second end is rotatable about the second pivot point as the lid moves between the open and closed positions; and wherein the spring is configured such that: the spring biases the lid towards the open position when the lid is between the open position and the intermediate position; and the spring biases the lid towards the closed position when the lid is between the intermediate position and the closed position. a housing delimiting an opening at one end, the opening being configured to receive aerosol generating material therein; a lid moveable from an open position where the opening is exposed, to a closed position where the opening is covered, via an intermediate position; and a spring, characterised in that: a first end of the spring is connected to the lid at a first pivot point and the first end is rotatable about the first pivot point as the lid moves between the open and closed positions; a second end of the spring is connected to the housing at a second pivot point and the second end is rotatable about the second pivot point as the lid moves between the open and closed positions; and wherein the spring is configured such that: the spring biases the lid towards the open position when the lid is between the open position and the intermediate position; and the spring biases the lid towards the closed position when the lid is between the intermediate position and the closed position. a first end of the spring is connected to the lid at a first pivot point and the first end is rotatable about the first pivot point as the lid moves between the open and closed positions; a second end of the spring is connected to the housing at a second pivot point and the second end is rotatable about the second pivot point as the lid moves between the open and closed positions; and wherein the spring is configured such that: the spring biases the lid towards the open position when the lid is between the open position and the intermediate position; and the spring biases the lid towards the closed position when the lid is between the intermediate position and the closed position.
A system for determining a computer model of realistic driving behavior for training an autonomous driving system, the system comprising: one or more environmental sensors configured to provide sensor data of observed vehicles (140-1, 140-2) within a traffic area; one or more position sensors installed on the observed vehicles (140-1, 140-2) providing positional data of the observed vehicles (140-1, 140-2); a processor configured to determine at least one error model by comparing the positional data with the sensor data of the one or more environmental sensors; extract observed vehicle behavior data from the sensor data and to extract driving behavior training data from observed vehicle behavior data of vehicles (140-1, 140-2) interacting with each other within the traffic area; and a machine learning based driving behavior simulator configured to: adjust driving behavior model parameters by reducing a deviation between the driving behavior training data modified by the at least one error model and simulated vehicle behavior data generated by the machine learning based driving behavior simulator and to train the autonomous driving system. one or more environmental sensors configured to provide sensor data of observed vehicles (140-1, 140-2) within a traffic area; one or more position sensors installed on the observed vehicles (140-1, 140-2) providing positional data of the observed vehicles (140-1, 140-2); a processor configured to determine at least one error model by comparing the positional data with the sensor data of the one or more environmental sensors; extract observed vehicle behavior data from the sensor data and to extract driving behavior training data from observed vehicle behavior data of vehicles (140-1, 140-2) interacting with each other within the traffic area; and a machine learning based driving behavior simulator configured to: adjust driving behavior model parameters by reducing a deviation between the driving behavior training data modified by the at least one error model and simulated vehicle behavior data generated by the machine learning based driving behavior simulator and to train the autonomous driving system.
A system for monitoring wind turbine loading, the system comprising: a main shaft; a bedplate; a gearbox coupled to the main shaft and mounted to the bedplate, the gearbox comprising an outer casing and a torque arm extending from the outer casing; an isolation mount coupled to the torque arm, wherein the torque arm and isolation mount each define a bore hole (74, 76) therethrough, and further defining a pin extending through the bore holes (74, 76) of the torque arm and the isolation mount, coupling the isolation mount to the torque arm, and a sensor configured to measure displacement of the torque arm, wherein the sensor is mounted within the isolation mount and is configured to indirectly measure displacement of the torque arm by measuring displacement of the pin. a bedplate; a gearbox coupled to the main shaft and mounted to the bedplate, the gearbox comprising an outer casing and a torque arm extending from the outer casing; an isolation mount coupled to the torque arm, wherein the torque arm and isolation mount each define a bore hole (74, 76) therethrough, and further defining a pin extending through the bore holes (74, 76) of the torque arm and the isolation mount, coupling the isolation mount to the torque arm, and a sensor configured to measure displacement of the torque arm, wherein the sensor is mounted within the isolation mount and is configured to indirectly measure displacement of the torque arm by measuring displacement of the pin.
Method for cultivating micro-organisms by confinement in micro-bioreactors, of the type comprising a carrier fluid for moving a train of droplets in a capillary tube comprising micro-bioreactors in which the culture of micro-organisms takes place that can modify the interfaces of said droplets, wherein said micro-bioreactors are separated by a spacing fluid, characterised in that said spacing fluid is a gas.
Electroacoustic transducer comprising: - a frame comprising a support, a first portion of a first structural layer disposed on the support and a cap disposed on the first portion of the first structural layer, the first structural layer having a thickness of less than 2 μm; - a element movable relative to the frame, the movable element comprising a membrane; - an internal cavity called back volume, subjected to a reference pressure and delimited by the mobile element and first and second walls (101, 102) belonging to the frame, the first wall being located as an extension of the membrane and the second wall being arranged facing the membrane; characterized in that the first wall comprises at least one sealed cavity separated from the back volume by the first portion of the first structural layer and in which a pressure lower than the reference pressure prevails in said at least one sealed cavity of the first wall. - a frame comprising a support, a first portion of a first structural layer disposed on the support and a cap disposed on the first portion of the first structural layer, the first structural layer having a thickness of less than 2 μm; - a element movable relative to the frame, the movable element comprising a membrane; - an internal cavity called back volume, subjected to a reference pressure and delimited by the mobile element and first and second walls (101, 102) belonging to the frame, the first wall being located as an extension of the membrane and the second wall being arranged facing the membrane;