A medical system (20; 120; 220) for engaging tissue, the medical system (20; 120; 220) comprising: a housing (42; 142; 242) defining an internal passageway and a longitudinal axis extending between proximal and distal ends of the housing (42; 142; 242); a first jaw rotatable relative to the housing, the first jaw having proximal and distal ends (64, 60); a second jaw rotatable relative to the housing, the second jaw having proximal and distal ends (66, 62); a driver engaged with the proximal ends (64, 66) of the first and second jaws (44, 46), longitudinal movement of the driver rotating the first and second jaws (44, 46) relative to the housing; an elongated drive wire selectively connected to the driver for longitudinal movement therewith, the drive wire having an enlarged portion proximate a distal end of the drive wire; and a tubular member defining a lumen; characterized in that the lumen is sized to slidably receive a connection block (26; 126; 226), the connection block (26; 126; 226) defining a bore (28; 128; 228) slidably receiving the drive wire, the enlarged portion of the drive wire having a size that is larger than the bore (28; 128; 228) and positioned on a distal side of the connection block (26; 126; 226); and the connection block (26; 126; 226) operable between an extended position and a retracted position, the connection block (26; 126; 226) projecting from the tubular member in the extended position and structured to engage a proximal end of the housing (42; 142; 242), the connection block (26; 126; 226) positioned within the lumen of the tubular member in the retracted position and disengaged from the housing (42; 142; 242), wherein the enlarged portion of the drive wire engages the connection block (26; 126; 226) upon proximal retraction of the drive wire to operate the tubular member from its extended position to its retracted position and disengage the connection block (26; 126; 226) from the housing (42; 142; 242). a housing (42; 142; 242) defining an internal passageway and a longitudinal axis extending between proximal and distal ends of the housing (42; 142; 242); a first jaw rotatable relative to the housing, the first jaw having proximal and distal ends (64, 60); a second jaw rotatable relative to the housing, the second jaw having proximal and distal ends (66, 62); a driver engaged with the proximal ends (64, 66) of the first and second jaws (44, 46), longitudinal movement of the driver rotating the first and second jaws (44, 46) relative to the housing; an elongated drive wire selectively connected to the driver for longitudinal movement therewith, the drive wire having an enlarged portion proximate a distal end of the drive wire; and a tubular member defining a lumen; characterized in that the lumen is sized to slidably receive a connection block (26; 126; 226), the connection block (26; 126; 226) defining a bore (28; 128; 228) slidably receiving the drive wire, the enlarged portion of the drive wire having a size that is larger than the bore (28; 128; 228) and positioned on a distal side of the connection block (26; 126; 226); and the connection block (26; 126; 226) operable between an extended position and a retracted position, the connection block (26; 126; 226) projecting from the tubular member in the extended position and structured to engage a proximal end of the housing (42; 142; 242), the connection block (26; 126; 226) positioned within the lumen of the tubular member in the retracted position and disengaged from the housing (42; 142; 242), wherein the enlarged portion of the drive wire engages the connection block (26; 126; 226) upon proximal retraction of the drive wire to operate the tubular member from its extended position to its retracted position and disengage the connection block (26; 126; 226) from the housing (42; 142; 242).