An ankle arthrodesis implant comprising: an elongate shaft sized and shaped to be implanted in an intramedullary canal of a tibia of a patient, the elongate shaft having an internal bore; wherein the implant further comprises: a first angled opening through the shaft, the first angled opening defining a first axis that extends through the tibia and into a talus bone of the patient across a tibio-talar joint when the implant is implanted; a first elongate slot through the shaft, the first elongate slot defining a second axis that extends into the patient's talus when the implantis implanted, the first elongate slot being configured to allow a first fixation member to translate axially relative to the shaft within the first slot from a first position to a second different position to compress a tibio-talar joint; a second elongate slot through the shaft, the second elongate slot defining a third axis that extends into the patient's calcaneus when the implant is implanted, the second elongate slot being configured to allow a second fixation member to translate axially relative to the shaft within the second slot from a first position to a second different position to compress a subtalar joint; and a second angled opening through the shaft, the second angled opening defining a third axis that extends into a calcaneus bone of the patient when the implant is implanted. an elongate shaft sized and shaped to be implanted in an intramedullary canal of a tibia of a patient, the elongate shaft having an internal bore; wherein the implant further comprises: a first angled opening through the shaft, the first angled opening defining a first axis that extends through the tibia and into a talus bone of the patient across a tibio-talar joint when the implant is implanted; a first elongate slot through the shaft, the first elongate slot defining a second axis that extends into the patient's talus when the implantis implanted, the first elongate slot being configured to allow a first fixation member to translate axially relative to the shaft within the first slot from a first position to a second different position to compress a tibio-talar joint; a second elongate slot through the shaft, the second elongate slot defining a third axis that extends into the patient's calcaneus when the implant is implanted, the second elongate slot being configured to allow a second fixation member to translate axially relative to the shaft within the second slot from a first position to a second different position to compress a subtalar joint; and a second angled opening through the shaft, the second angled opening defining a third axis that extends into a calcaneus bone of the patient when the implant is implanted. a first angled opening through the shaft, the first angled opening defining a first axis that extends through the tibia and into a talus bone of the patient across a tibio-talar joint when the implant is implanted; a first elongate slot through the shaft, the first elongate slot defining a second axis that extends into the patient's talus when the implantis implanted, the first elongate slot being configured to allow a first fixation member to translate axially relative to the shaft within the first slot from a first position to a second different position to compress a tibio-talar joint; a second elongate slot through the shaft, the second elongate slot defining a third axis that extends into the patient's calcaneus when the implant is implanted, the second elongate slot being configured to allow a second fixation member to translate axially relative to the shaft within the second slot from a first position to a second different position to compress a subtalar joint; and a second angled opening through the shaft, the second angled opening defining a third axis that extends into a calcaneus bone of the patient when the implant is implanted.