An endotracheal tube for use in a method of wire-guided intubation of a patient, said endotracheal tube comprising: a) a side wall enclosing a main lumen, the side wall being composed of a flexible material so as to follow the shape of the airway path (85, 90) into the trachea of a patient, the side wall having the flexible material of most of its length reinforced to prevent kinking thereof during its intubation, use, and extubation, b) a proximal end portion of the tube suitable for attachment to a breathing circuit and which is configured to protrude in use from the mouth or nose of the patient, c) a distal end portion of the tube for insertion into the nose or into the mouth of the patient so as to enter the airway (85, 90) in the direction leading to the trachea, the distal end portion having a bevelled end, wherein the flexible material of which the bevelled end is composed is non-reinforced and is more readily deformable relative to the reinforced material, the bevelled end having a tip which is shaped and configured to traverse the laryngeal inlet of the patient during the wire-guided intubation procedure, and characterized in that the endotracheal tube further comprises d) a guiding channel at said sidewall of the tube wherein said guiding channel is a smooth continuous lumen which extends from a proximal opening of the guiding channel at said proximal end portion to a distal opening of the guiding channel at said tip, wherein said guiding channel is configured to slidingly receive during the wire-guided intubation procedure an anterograde or retrograde guide wire configured to extend into the trachea of the patient from the mouth or nose of the patient whereby the tip follows the guide wire into the trachea of the patient. a) a side wall enclosing a main lumen, the side wall being composed of a flexible material so as to follow the shape of the airway path (85, 90) into the trachea of a patient, the side wall having the flexible material of most of its length reinforced to prevent kinking thereof during its intubation, use, and extubation, b) a proximal end portion of the tube suitable for attachment to a breathing circuit and which is configured to protrude in use from the mouth or nose of the patient, c) a distal end portion of the tube for insertion into the nose or into the mouth of the patient so as to enter the airway (85, 90) in the direction leading to the trachea, the distal end portion having a bevelled end, wherein the flexible material of which the bevelled end is composed is non-reinforced and is more readily deformable relative to the reinforced material, the bevelled end having a tip which is shaped and configured to traverse the laryngeal inlet of the patient during the wire-guided intubation procedure, and characterized in that the endotracheal tube further comprises d) a guiding channel at said sidewall of the tube wherein said guiding channel is a smooth continuous lumen which extends from a proximal opening of the guiding channel at said proximal end portion to a distal opening of the guiding channel at said tip, wherein said guiding channel is configured to slidingly receive during the wire-guided intubation procedure an anterograde or retrograde guide wire configured to extend into the trachea of the patient from the mouth or nose of the patient whereby the tip follows the guide wire into the trachea of the patient.