mhurhangee/ep-ind-claims huggingface dataset:
A blunt impact indicator device, comprising: a substrate comprising first and second surfaces; and a multiplicity of rupturable shells disposed in proximity to said first surface of said substrate, characterized in that an electrically conductive fluid is disposed in an internal volume of the shells, wherein the electrically conductive fluid comprises a colloidal graphite suspension. a substrate comprising first and second surfaces; and a multiplicity of rupturable shells disposed in proximity to said first surface of said substrate, characterized in that an electrically conductive fluid is disposed in an internal volume of the shells, wherein the electrically conductive fluid comprises a colloidal graphite suspension.
Clutch cover arrangement for a clutch, having a clutch cover, wherein the clutch cover has at least one housing opening which is delimited by a wall, and having at least one balancing element which is inserted into the housing opening and which serves for balancing the clutch, wherein the balancing element has a shank for insertion into the housing opening of the clutch cover and has a head which projects axially from the shank and which serves for limiting an insertion depth, characterized in that the balancing element furthermore has cutting edges which protrude radially from the shank and which serve for plastically deforming a wall surrounding the housing opening, wherein, between the cutting edges and the head, there is provided a deformation stop which is arranged spaced apart from the cutting edges and which serves for plastically deforming a part of the wall between the cutting edges and the deformation stop, wherein the balancing element is received in captively retained fashion as a result of the deformation of the wall by the deformation stop.
A connection unit for connecting an electrical supply line to an exhaust-gas heater of an exhaust system of an internal combustion engine, comprising: - a connection element having an electrically conductive connection-element body that is elongate in the direction of a longitudinal axis, the connection element having an exhaust-gas heater connection region in a first axial end region and having a supply-line connection region in a second axial end region, the supply-line connection region comprising an end portion of the connection-element body, - a carrier element for fixing the connection unit to an exhaust-system component, the carrier element having a carrier-element opening through which the connection-element body passes at a radial distance from the carrier element, - a support unit for axially and radially supporting the connection element on the carrier element, the support unit comprising a first support element of electrically insulating material supported on the carrier element in a first axial direction (R 1) and radially outwardly, and a second support element of electrically insulating material supported on the carrier element in the second axial direction (R 2) and radially outwardly, characterized in that the supply-line connection region comprises a radial projection of the connection-element body forming an integral part of said connection-element body and adjoining the end portion, and in that the first support element is supported in relation to the radial projection in a second axial direction (R 2) opposed to the first axial direction (R 1). - a connection element having an electrically conductive connection-element body that is elongate in the direction of a longitudinal axis, the connection element having an exhaust-gas heater connection region in a first axial end region and having a supply-line connection region in a second axial end region, the supply-line connection region comprising an end portion of the connection-element body, - a carrier element for fixing the connection unit to an exhaust-system component, the carrier element having a carrier-element opening through which the connection-element body passes at a radial distance from the carrier element, - a support unit for axially and radially supporting the connection element on the carrier element, the support unit comprising a first support element of electrically insulating material supported on the carrier element in a first axial direction (R 1) and radially outwardly, and a second support element of electrically insulating material supported on the carrier element in the second axial direction (R 2) and radially outwardly,
A neuroprotective peptide for inhibiting Mitogen-activated protein kinase 3 (MAPK3) protein kinase signalling consisting of an amino acid sequence: i) QGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDV (SEQ ID NO:1) hereafter named RB5; or ii) a sequence having at least 96% identity with peptide i). i) QGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDV (SEQ ID NO:1) hereafter named RB5; or ii) a sequence having at least 96% identity with peptide i).
A library of cells presenting candidate peptides in a peptide display scaffold suitable to identify a peptide that interacts with a peptidase, wherein the peptide display scaffold comprises a fusion protein comprising: [D 1 -C 1]-TM-[D 2]; wherein D 1 -C 1 and D 2 are accessible at a surface of the cell outermembrane; wherein TM is a transmembrane protein selected from a bacterial outer membrane protein (Omp) that has been rearranged for terminal fusion display from an internal loop,preferably from OmpA, OmpX, OmpT, OmpC, or OmpS; wherein C 1 is a candidate substrate for a peptidase; wherein D 1 and D 2 are first and second detectable moieties, wherein D 1 and D 2 are different; wherein D 1 -C 1 may be at either the N-terminus or the C-terminus and D 2 may be at either the N-terminus or the C-terminus; and wherein the cells of the cell library exhibit a D 1 signal prior to contacting with the peptidase, and wherein an increase in the D 2 signal relative to the D 1 signal indicates that at least one cell of the cell library expresses a candidate substrate for the peptidase which is cleaved, thereby releasing the domain having the D 1 detectable moiety. D 1 -C 1 and D 2 are accessible at a surface of the cell outermembrane; wherein TM is a transmembrane protein selected from a bacterial outer membrane protein (Omp) that has been rearranged for terminal fusion display from an internal loop,preferably from OmpA, OmpX, OmpT, OmpC, or OmpS; wherein C 1 is a candidate substrate for a peptidase; wherein D 1 and D 2 are first and second detectable moieties, wherein D 1 and D 2 are different; wherein D 1 -C 1 may be at either the N-terminus or the C-terminus and D 2 may be at either the N-terminus or the C-terminus; and wherein the cells of the cell library exhibit a D 1 signal prior to contacting with the peptidase, and wherein an increase in the D 2 signal relative to the D 1 signal indicates that at least one cell of the cell library expresses a candidate substrate for the peptidase which is cleaved, thereby releasing the domain having the D 1 detectable moiety.
A compound of formula a tautomer thereof, or a pharmaceutically acceptable salt of said compound or tautomer, wherein: R 1 is selected from (C 1 -C 4)alkyl, (C 1 -C 4)fluoroalkyl and CH 2 OCH 3; R 2, R 3 and R 4 are each independently selected from hydrogen and fluorine; and R 5 is selected from hydrogen, fluorine, (C 1 -C 4)alkoxy and cyclopropoxy. R 1 is selected from (C 1 -C 4)alkyl, (C 1 -C 4)fluoroalkyl and CH 2 OCH 3; R 2, R 3 and R 4 are each independently selected from hydrogen and fluorine; and R 5 is selected from hydrogen, fluorine, (C 1 -C 4)alkoxy and cyclopropoxy.
A disc brake assembly comprising: an anchor bracket having at least one bore formed therein, the bore defining a first axis; a brake caliper slidably secured to the anchor bracket; a pair of brake pads carried by the disc brake assembly; and at least one guide pin adapted to be disposed in the bore of the anchor bracket, the at least one guide pin defining a second axis; characterised in that when the at least one guide pin is disposed in the at least one bore of the anchor bracket, the second axis of the at least one guide pin is configured to be offset relative to the first axis of the at least one bore such that there is provided at least one defined point of contact between only a portion of a shank portion of the at least one guide pin and a portion of an inner surface of the at least one bore. an anchor bracket having at least one bore formed therein, the bore defining a first axis; a brake caliper slidably secured to the anchor bracket; a pair of brake pads carried by the disc brake assembly; and at least one guide pin adapted to be disposed in the bore of the anchor bracket, the at least one guide pin defining a second axis; characterised in that when the at least one guide pin is disposed in the at least one bore of the anchor bracket, the second axis of the at least one guide pin is configured to be offset relative to the first axis of the at least one bore such that there is provided at least one defined point of contact between only a portion of a shank portion of the at least one guide pin and a portion of an inner surface of the at least one bore.
An oral pharmaceutical composition, comprising MGBG together with at least one oral pharmaceutically acceptable excipient, for use in the treatment of pain when orally administered to a subject.
A strut-type suspension comprising: a lower spring seat; an upper spring seat; a compression coil spring which comprises a wire that is formed into a helical shape, and is arranged in such a state that it is compressed between the lower spring seat and the upper spring seat; and a shock absorber which comprises a cylinder and a rod which is inserted into the cylinder, the shock absorber passing through an inside of the compression coil spring, characterized in that a coil central axis of the compression coil spring is offset to an outer side of a vehicle with respect to an axis of the shock absorber, and the wire of the compression coil spring comprises: a counter-offset-side large-diameter wire portion which is arranged more toward an inner side of the vehicle than the axis of the shock absorber, and has a wire diameter which is greater than an average wire diameter of the wire; an offset-side small-diameter wire portion which is arranged more toward the outer side of the vehicle than the axis of the shock absorber, and has a wire diameter which is smaller than the wire diameter of the large-diameter wire portion; and a wire diameter varying portion whose wire diameter is continuously varied between the large-diameter wire portion and the small-diameter wire portion. a lower spring seat; an upper spring seat; a compression coil spring which comprises a wire that is formed into a helical shape, and is arranged in such a state that it is compressed between the lower spring seat and the upper spring seat; and a shock absorber which comprises a cylinder and a rod which is inserted into the cylinder, the shock absorber passing through an inside of the compression coil spring, characterized in that a coil central axis of the compression coil spring is offset to an outer side of a vehicle with respect to an axis of the shock absorber, and the wire of the compression coil spring comprises: a counter-offset-side large-diameter wire portion which is arranged more toward an inner side of the vehicle than the axis of the shock absorber, and has a wire diameter which is greater than an average wire diameter of the wire; an offset-side small-diameter wire portion which is arranged more toward the outer side of the vehicle than the axis of the shock absorber, and has a wire diameter which is smaller than the wire diameter of the large-diameter wire portion; and a wire diameter varying portion whose wire diameter is continuously varied between the large-diameter wire portion and the small-diameter wire portion. a counter-offset-side large-diameter wire portion which is arranged more toward an inner side of the vehicle than the axis of the shock absorber, and has a wire diameter which is greater than an average wire diameter of the wire; an offset-side small-diameter wire portion which is arranged more toward the outer side of the vehicle than the axis of the shock absorber, and has a wire diameter which is smaller than the wire diameter of the large-diameter wire portion; and a wire diameter varying portion whose wire diameter is continuously varied between the large-diameter wire portion and the small-diameter wire portion.
A mining machine comprising: a chassis including a first end and a second end, the chassis defining a chassis axis extending between the first end and the second end; a boom including a first end and a second end, the boom supported for movement relative to the chassis, the boom translating in a first direction, the boom pivotable relative to the chassis between a first position and a second position; a cutting head coupled to the second end of the boom and supported for rotation relative to the boom, the cutting head rotatable about a cutting head axis; and characterized by a shield supported for movement relative to the chassis and positioned proximate the cutting head, the shield and the boom being coupled to a sumping frame supported for translational movement relative to the chassis along the chassis axis, wherein the pivoting movement of the boom is controlled independently of the translational movement of the boom. a chassis including a first end and a second end, the chassis defining a chassis axis extending between the first end and the second end; a boom including a first end and a second end, the boom supported for movement relative to the chassis, the boom translating in a first direction, the boom pivotable relative to the chassis between a first position and a second position; a cutting head coupled to the second end of the boom and supported for rotation relative to the boom, the cutting head rotatable about a cutting head axis; and characterized by a shield supported for movement relative to the chassis and positioned proximate the cutting head, the shield and the boom being coupled to a sumping frame supported for translational movement relative to the chassis along the chassis axis, wherein the pivoting movement of the boom is controlled independently of the translational movement of the boom.
A strip ejection system for holding and ejecting a disposable strip filled with a biological sample (1; 10), the system comprising: a meter comprising a meter casing (4; 30); a disposable strip filled with a biological sample (1; 10) disposed at least in part within the casing (4; 30); and a strip moving section (2; 20; 70), the strip moving section comprising all elements of the system that are involved with moving the strip (1; 10), the strip moving section comprising a pressing element (2; 20) for pressing against the strip to move the strip from a first position to a different second position relative to the casing, wherein the pressing element (2; 20) is the only element of the strip moving section that is movably arranged relative to the casing (4; 30), and wherein the pressing element (2; 20) is configured to be pressed against a flat face of the strip, characterised in that the pressing element is rotatable. a meter comprising a meter casing (4; 30); a disposable strip filled with a biological sample (1; 10) disposed at least in part within the casing (4; 30); and a strip moving section (2; 20; 70), the strip moving section comprising all elements of the system that are involved with moving the strip (1; 10), the strip moving section comprising a pressing element (2; 20) for pressing against the strip to move the strip from a first position to a different second position relative to the casing, wherein the pressing element (2; 20) is the only element of the strip moving section that is movably arranged relative to the casing (4; 30), and wherein the pressing element (2; 20) is configured to be pressed against a flat face of the strip, characterised in that the pressing element is rotatable.
A traffic offloading method, wherein a first network node and a second network node are connected by using a first data link and a second data link, a first forwarding tunnel from the first network node to the second network node is established on the first data link, and the first network node and the second network node are respectively a tunnel endpoint of the first forwarding tunnel; and the method comprises: calculating (S201, S401), by the first network node, a first packet loss rate of the first forwarding tunnel in a preset period; when the first packet loss rate is higher than a first preset threshold, reducing (S202, S402), by the first network node, a rated bandwidth of the first forwarding tunnel by a first preset bandwidth, so as to obtain a first available bandwidth, wherein the rated bandwidth of the first forwarding tunnel refers to a size of a bandwidth allocated by the first data link to the first forwarding tunnel; when traffic forwarded over the first forwarding tunnel exceeds the first available bandwidth, offloading (S203, S403), by the first network node, excess to-be-forwarded traffic to the second data link for forwarding; and when the first packet loss rate is lower than a second preset threshold, increasing, by the first network node, the first available bandwidth by a second preset bandwidth, so as to obtain a second available bandwidth, wherein the second preset bandwidth is less than or equal to the first preset bandwidth, and the second available bandwidth is less than or equal to the rated bandwidth of the first forwarding tunnel that is of the first data link and that is from the first network node to the second network node. calculating (S201, S401), by the first network node, a first packet loss rate of the first forwarding tunnel in a preset period; when the first packet loss rate is higher than a first preset threshold, reducing (S202, S402), by the first network node, a rated bandwidth of the first forwarding tunnel by a first preset bandwidth, so as to obtain a first available bandwidth, wherein the rated bandwidth of the first forwarding tunnel refers to a size of a bandwidth allocated by the first data link to the first forwarding tunnel; when traffic forwarded over the first forwarding tunnel exceeds the first available bandwidth, offloading (S203, S403), by the first network node, excess to-be-forwarded traffic to the second data link for forwarding; and when the first packet loss rate is lower than a second preset threshold, increasing, by the first network node, the first available bandwidth by a second preset bandwidth, so as to obtain a second available bandwidth, wherein the second preset bandwidth is less than or equal to the first preset bandwidth, and the second available bandwidth is less than or equal to the rated bandwidth of the first forwarding tunnel that is of the first data link and that is from the first network node to the second network node.
A biopsy forceps tool comprising: a coaxial cable for conveying microwave energy, the coaxial cable having an inner conductor, an outer conductor and a layer of dielectric material separating the inner conductor from the outer conductor; and a jaw assembly mounted at a distal end of the coaxial cable, the jaw assembly comprising a pair of jaws (212a, 212b), each of the pair of jaws comprising an electrically conductive shell, the jaw assembly being operable to change a relative position of the pair of jaws between a closed position in which the electrically conductive shells engage each other to enclose an internal volume for holding a tissue sample and an open position in which the electrically conductive shells are separated to expose the internal volume in order to receive the tissue sample, wherein the electrically conductive shells form a Faraday cage around the internal volume when in the closed position, wherein the coaxial cable is connected to deliver microwave energy to the jaw assembly to be emitted as a microwave field, and wherein the Faraday cage is configured to shield the internal volume from the microwave energy supplied by the coaxial cable. a coaxial cable for conveying microwave energy, the coaxial cable having an inner conductor, an outer conductor and a layer of dielectric material separating the inner conductor from the outer conductor; and a jaw assembly mounted at a distal end of the coaxial cable, the jaw assembly comprising a pair of jaws (212a, 212b), each of the pair of jaws comprising an electrically conductive shell, the jaw assembly being operable to change a relative position of the pair of jaws between a closed position in which the electrically conductive shells engage each other to enclose an internal volume for holding a tissue sample and an open position in which the electrically conductive shells are separated to expose the internal volume in order to receive the tissue sample, wherein the electrically conductive shells form a Faraday cage around the internal volume when in the closed position, wherein the coaxial cable is connected to deliver microwave energy to the jaw assembly to be emitted as a microwave field, and wherein the Faraday cage is configured to shield the internal volume from the microwave energy supplied by the coaxial cable.
A power take off drive train for a utility vehicle, comprising: - first (31, 59), second (35, 55) and third (23, 68) parallel gear pairs; - an input shaft coupled to a gear of the first gear pain (31, 59), - first and second connector means (K1, K2), each operable to couple a gear of the first gear pair (31, 59) with a gear of the second gear peir (35, 55), - third connector means coupling a first gear of the second gear pain (35, 55) with a first gear of the third gear pair (23, 68), - an output shaf; characterised in by - selector means operable to couple the output shaft with either a second gear of the second gear pair (35, 55) or a second gean of the third gear pair (23, 68). - first (31, 59), second (35, 55) and third (23, 68) parallel gear pairs; - an input shaft coupled to a gear of the first gear pain (31, 59), - first and second connector means (K1, K2), each operable to couple a gear of the first gear pair (31, 59) with a gear of the second gear peir (35, 55), - third connector means coupling a first gear of the second gear pain (35, 55) with a first gear of the third gear pair (23, 68), - an output shaf; characterised in by - selector means operable to couple the output shaft with either a second gear of the second gear pair (35, 55) or a second gean of the third gear pair (23, 68).
A wrapper housing a food product, in particular a confectionary product, comprising: - a wrapping sheet shaped so as to define a curved portion within which said product is housed; wherein said sheet is folded on itself so as to define said curved portion and a peripheral portion along which a sealing line is made, and wherein the sheet comprises a tear strip applied on the inner side of said sheet so as to traverse at least one part of said curved portion, wherein at least one end of said tear strip is set in said curved portion; wherein said sheet has at least one cut made in a position corresponding to said end of said tear strip, which is designed to define a point for triggering tearing of said sheet; characterized in that - said one end of said tear strip, and the cut, are placed at the curved portion, at a given distance from said peripheral portion; - an adhesive label is applied on the outer side of said curved portion and applied on said cut so as to close any communication through the cut between the inside and the outside of said curved portion. - a wrapping sheet shaped so as to define a curved portion within which said product is housed; - said one end of said tear strip, and the cut, are placed at the curved portion, at a given distance from said peripheral portion; - an adhesive label is applied on the outer side of said curved portion and applied on said cut so as to close any communication through the cut between the inside and the outside of said curved portion.