mhurhangee/ep-ind-claims huggingface dataset:
Device for real-time detection of aeropathogens comprising an aerosampler having an air inlet and at least one air collector tube (15, 16); a microfluidic system comprising at least one container for receiving a wetting liquid, piping from the container to the at least one air collector tube and at least one micro pump for creating fluid flow through the piping; the at least one container being configured to supply wetting liquid to an inner wall of the least one collector tube (15, 16); and the air inlet being configured to inject air into the at least one collector tube eccentrically and oblique to a bottom of the tube thereby creating a centrifugal force; the device further comprising at least one aeropathogen detection chamber and piping from microfluidic system to the at last one aeropathogen detection chamber, the detection chamber having at least one working electrode being equipped with a functionalized aptamer for binding to an aeropathogen, at least one counter electrode and at least one reference electrode; at least one electronic detection system connectable to the electrodes of the at least one aeropathogen detection chamber; and an embedded electronic processing system processing data receivable from the at least one electronic detection system.
A support assembly for a gas turbine engine, the support assembly comprising: an outer casing defining a longitudinal central axis; an inner structure comprising a platform defining an aperture therethrough and a support portion disposed around the platform; a strut extending generally radially from the inner structure to the outer casing with respect to the longitudinal central axis, wherein the strut is coupled to the outer casing; and a mechanical fastener received through the aperture of the platform and at least partially received within the strut to couple the strut to the platform; the support assembly being characterised in that: the support portion defines a slot therethrough adjacent to the platform, wherein the slot at least partially surrounds the platform and extends axially towards the aperture by an axial slot length along the longitudinal central axis; the platform flexes relative to the support portion at the slot to form a flexible joint between the strut and the inner structure; and the slot comprises a base extending circumferentially relative to the longitudinal central axis and a pair of arms extending axially from the base towards the aperture, wherein each arm has the axial slot length along the longitudinal central axis. an outer casing defining a longitudinal central axis; an inner structure comprising a platform defining an aperture therethrough and a support portion disposed around the platform; a strut extending generally radially from the inner structure to the outer casing with respect to the longitudinal central axis, wherein the strut is coupled to the outer casing; and a mechanical fastener received through the aperture of the platform and at least partially received within the strut to couple the strut to the platform; the support assembly being characterised in that: the support portion defines a slot therethrough adjacent to the platform, wherein the slot at least partially surrounds the platform and extends axially towards the aperture by an axial slot length along the longitudinal central axis; the platform flexes relative to the support portion at the slot to form a flexible joint between the strut and the inner structure; and the slot comprises a base extending circumferentially relative to the longitudinal central axis and a pair of arms extending axially from the base towards the aperture, wherein each arm has the axial slot length along the longitudinal central axis. the support portion defines a slot therethrough adjacent to the platform, wherein the slot at least partially surrounds the platform and extends axially towards the aperture by an axial slot length along the longitudinal central axis; the platform flexes relative to the support portion at the slot to form a flexible joint between the strut and the inner structure; and the slot comprises a base extending circumferentially relative to the longitudinal central axis and a pair of arms extending axially from the base towards the aperture, wherein each arm has the axial slot length along the longitudinal central axis.
Panel comprising at least a substrate of thermoplastic material and a top layer with a printed decor and a translucent or transparent wear layer, wherein said substrate substantially consists of three layers, including a lowermost layer, a central layer and an uppermost layer, all made from thermoplastic material, characterized in that the thermoplastic material of the lowermost layer and the uppermost layer is more rigid than the thermoplastic material of the central layer, wherein said lowermost layer is on the basis of hard or semi-rigid polyvinylchloride, said central layer is on the basis of soft polyvinylchloride, and said uppermost layer is on the basis of hard or semi-rigid polyvinylchloride, wherein said lowermost and said uppermost layer comprise less than 5 percent by weight of plasticizer or no plasticizer, said central layer comprises 12 percent by weight or more of plasticizer.
A fiber optic cable, having a core comprising an optical fiber and a jacket surrounding the core, wherein the jacket has an interior surface that faces the core and an exterior surface, wherein the jacket is formed primarily from a polymer material, wherein the jacket comprises: a discontinuity extending lengthwise along the cable and wholly embedded in the jacket, a tactile indicator extending lengthwise along the exterior of the jacket denoting the location of the wholly-embedded discontinuity of the jacket, wherein the discontinuity comprises a portion of the jacket of a different material composition than a main portion of the jacket, the main portion of the jacket being an annular hoop surrounding the core, whereby the discontinuity provides a line of weakness that allows the jacket to be separated to provide access to the core, wherein the main portion of the jacket is formed from a first material comprising at least 80% by weight of a first polymer, and wherein the discontinuity is formed from a second material comprising at least 70% by weight of a second polymer and at least 0.5% by weight of the first polymer, thereby increasing bonding between the discontinuity and the main portion of the jacket, and wherein the discontinuity is bonded to the main portion of the jacket such that the jacket comprises a cohesive composite polymer structure. a discontinuity extending lengthwise along the cable and wholly embedded in the jacket, a tactile indicator extending lengthwise along the exterior of the jacket denoting the location of the wholly-embedded discontinuity of the jacket, wherein the discontinuity comprises a portion of the jacket of a different material composition than a main portion of the jacket, the main portion of the jacket being an annular hoop surrounding the core, whereby the discontinuity provides a line of weakness that allows the jacket to be separated to provide access to the core, wherein the main portion of the jacket is formed from a first material comprising at least 80% by weight of a first polymer, and wherein the discontinuity is formed from a second material comprising at least 70% by weight of a second polymer and at least 0.5% by weight of the first polymer, thereby increasing bonding between the discontinuity and the main portion of the jacket, and wherein the discontinuity is bonded to the main portion of the jacket such that the jacket comprises a cohesive composite polymer structure.
A power control device, the power control device comprising: a modem, a first power management module connected to the modem, an application processor, AP, a second power management module connected to the AP, and a control module connected to the AP, the first power management module and the second power management module; wherein the second power management module is configured to output a second control signal to the first power management module before the AP receives a shutdown instruction or an abnormal power-down is detected; the AP is configured to generate a first control signal and output the first control signal to the control module in a case that a shutdown instruction is received or an abnormal power-down is detected; the control module is configured to convert the second control signal into a third control signal under control of the first control signal, so that the second power management module outputs the third control signal to the first power management module; the first power management module is configured to stop power supply to the modem under control of the third control signal. the second power management module is configured to output a second control signal to the first power management module before the AP receives a shutdown instruction or an abnormal power-down is detected; the AP is configured to generate a first control signal and output the first control signal to the control module in a case that a shutdown instruction is received or an abnormal power-down is detected; the control module is configured to convert the second control signal into a third control signal under control of the first control signal, so that the second power management module outputs the third control signal to the first power management module; the first power management module is configured to stop power supply to the modem under control of the third control signal.
A compound selected from the group consisting of: N-(4-(4-(2-(tert-Butyl)-6-methylpyrimidin-4-yl)piperazin-1-yl)butyl)-4-phenylpiperazine-1-carboxamide, N-(4-(4-(6-(tert-Butyl)-2-methylpyrimidin-4-yl)piperazin-1-yl)butyl)-4-phenylpiperazine-1-carboxamide, N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-4-phenylpiperazine-1-carboxamide, 4-Phenyl-N-(4-(4-(quinolin-4-yl)piperazin-1-yl)butyl)piperazine-1-carboxamide, N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-3-(pyridin-4-yl)azetidine-1-carboxamide, N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-5-methoxyisoindoline-2-carboxamide, N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-4,5-dihydro-1H-benzo[d]azepine-3 -carboxamide, N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-4-phenylpiperidine-1-carboxamide, N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-3,4-dihydro-1H-pyrido[4,3-b]indole-2 -carboxamide, N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-4-phenylcyclohexanecarboxamide, 4-Phenyl-N-(4-(4-(quinolin-4-yl)piperazin-1-yl)butyl)cyclohexanecarboxamide, N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)imidazo[1,2-a]pyridine-2-carboxamide, and/or pharmaceutically acceptable salt thereof. N-(4-(4-(2-(tert-Butyl)-6-methylpyrimidin-4-yl)piperazin-1-yl)butyl)-4-phenylpiperazine-1-carboxamide, N-(4-(4-(6-(tert-Butyl)-2-methylpyrimidin-4-yl)piperazin-1-yl)butyl)-4-phenylpiperazine-1-carboxamide, N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-4-phenylpiperazine-1-carboxamide, 4-Phenyl-N-(4-(4-(quinolin-4-yl)piperazin-1-yl)butyl)piperazine-1-carboxamide, N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-3-(pyridin-4-yl)azetidine-1-carboxamide, N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-5-methoxyisoindoline-2-carboxamide, N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-4,5-dihydro-1H-benzo[d]azepine-3 -carboxamide, N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-4-phenylpiperidine-1-carboxamide, N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-3,4-dihydro-1H-pyrido[4,3-b]indole-2 -carboxamide, N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-4-phenylcyclohexanecarboxamide, 4-Phenyl-N-(4-(4-(quinolin-4-yl)piperazin-1-yl)butyl)cyclohexanecarboxamide, N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)imidazo[1,2-a]pyridine-2-carboxamide,
A crystalline form of a di-hydrochloride monohydrate salt of 4-(2-((1R,2R)-2-hydroxycyclohexylamino)benzothiazol-6-yloxy)-N-methylpicolinamide characterized by an X-ray powder diffraction pattern comprising peaks at 7.3 ± 0.2 °2θ and 12.1 ± 0.2 °2θ, when measured using CuKα radiation with a wavelength of 1.5418 Å and at a temperature of about 22°C.
An autonomous coverage robot (100,101) comprising: a chassis having forward and rearward portions (210, 220), the forward portion defining a substantially rectangular shape and the rearward portion defining an arcuate shape; a drive system carried by the chassis configured to maneuver the robot (100, 101) over a cleaning surface; right and left differentially driven drive wheels (410, 420); a cleaning assembly mounted on the forward portion of the chassis; a bin disposed adjacent the cleaning assembly and configured to receive debris agitated by the cleaning assembly; a bump sensor configured to detect movement in multiple directions; characterized in that the cleaning assembly comprises: a first roller brush rotatably mounted near a front edge of the chassis; and a second roller brush rotatably mounted substantially parallel to and rearward of the first roller brush, the first and second roller brushes (510, 520) rotating in opposite directions. a chassis having forward and rearward portions (210, 220), the forward portion defining a substantially rectangular shape and the rearward portion defining an arcuate shape; a drive system carried by the chassis configured to maneuver the robot (100, 101) over a cleaning surface; right and left differentially driven drive wheels (410, 420); a cleaning assembly mounted on the forward portion of the chassis; a bin disposed adjacent the cleaning assembly and configured to receive debris agitated by the cleaning assembly; a bump sensor configured to detect movement in multiple directions; characterized in that the cleaning assembly comprises: a first roller brush rotatably mounted near a front edge of the chassis; and a second roller brush rotatably mounted substantially parallel to and rearward of the first roller brush, the first and second roller brushes (510, 520) rotating in opposite directions. a first roller brush rotatably mounted near a front edge of the chassis; and a second roller brush rotatably mounted substantially parallel to and rearward of the first roller brush, the first and second roller brushes (510, 520) rotating in opposite directions.
An apparatus, comprising: at least one processor; and at least one memory including computer program code, the at least one memory and the computer program code configured to, with the at least one processor, cause the apparatus at least to: serve one or more cells of a radio access system, the geographical area of the radio access system comprising one or more authorized/licenced shared access reservation zones, where the use of the resources of the zones may be activated or deactivated by a network element of the system characterised in that, for each served cell store category classification information, the category classification describing how the cell interferes with each of the one or more authorized/licenced shared access reservation zones; store one or more predetermined actions for each category classification and reservation zone; receive a command from a network element related to the activation or deactivation of one or more authorized/licenced shared access reservation zones; execute one or more predetermined actions on the basis of the command. at least one processor; and at least one memory including computer program code, the at least one memory and the computer program code configured to, with the at least one processor, cause the apparatus at least to: serve one or more cells of a radio access system, the geographical area of the radio access system comprising one or more authorized/licenced shared access reservation zones, where the use of the resources of the zones may be activated or deactivated by a network element of the system characterised in that, for each served cell store category classification information, the category classification describing how the cell interferes with each of the one or more authorized/licenced shared access reservation zones; store one or more predetermined actions for each category classification and reservation zone; receive a command from a network element related to the activation or deactivation of one or more authorized/licenced shared access reservation zones; execute one or more predetermined actions on the basis of the command. serve one or more cells of a radio access system, the geographical area of the radio access system comprising one or more authorized/licenced shared access reservation zones, where the use of the resources of the zones may be activated or deactivated by a network element of the system characterised in that, for each served cell store category classification information, the category classification describing how the cell interferes with each of the one or more authorized/licenced shared access reservation zones; store one or more predetermined actions for each category classification and reservation zone; receive a command from a network element related to the activation or deactivation of one or more authorized/licenced shared access reservation zones; execute one or more predetermined actions on the basis of the command.
A method for degrading a superabsorbent polymer to poly(acrylic acid) comprising flowing a feed stream comprising said SAP into a UV irradiation zone, irradiating said feed stream with UV, and producing a product stream comprising said PAA at the end of said irradiation zone; wherein said feed stream comprises said SAP at a concentration greater than 1 wt%; wherein said feed stream has a residence time in said UV irradiation zone of less than 120 s; and wherein said UV used to convert SAP to PAA requires a UV total energy of less than 50 MJ/kg SAP.
A coated detergent particle having perpendicular dimensions x, y and z, wherein x is from 1 to 2 mm, y is from 2 to 8mm, and z is from 2 to 8 mm, wherein the particle comprises: (i) from 40 to 90 wt % surfactant selected from: anionic surfactant; and, non-ionic surfactant; (ii) from 20 to 40 wt% water soluble inorganic salts, the water soluble inorganic salts a mixture of sodium carbonate and sodium silicate; and, (iii) from 0 to 3 wt % of a perfume, wherein the inorganic salts are present on the detergent particle as a coating and the surfactant is present as a core and sodium carbonate and sodium silicate comprise from 70 to 100 wt % of the coating and the ratio of sodium carbonate:sodium silicate in the coating is in the range from 4:1 to 2:3. (i) from 40 to 90 wt % surfactant selected from: anionic surfactant; and, non-ionic surfactant; (ii) from 20 to 40 wt% water soluble inorganic salts, the water soluble inorganic salts a mixture of sodium carbonate and sodium silicate; and, (iii) from 0 to 3 wt % of a perfume,
A cannula assembly, which comprises: a housing; and a cannula member connected to the housing, the cannula member having leading and trailing ends and defining a longitudinal axis, the cannula member including: a main body; a seal adjacent the leading end, the seal capable of receiving an instrument therethrough while maintaining a substantial sealed relation with the instrument; and a flexible portion disposed between the main body and the seal, the flexible portion being configured to permit movement of the seal relative to the longitudinal axis during manipulation of the endoscopic instrument, wherein the flexible portion includes a bellow defined by a plurality of continuous bellows and characterised in that the plurality of continuous bellows include inner and outer continuous bellows. a housing; and a cannula member connected to the housing, the cannula member having leading and trailing ends and defining a longitudinal axis, the cannula member including: a main body; a seal adjacent the leading end, the seal capable of receiving an instrument therethrough while maintaining a substantial sealed relation with the instrument; and a flexible portion disposed between the main body and the seal, the flexible portion being configured to permit movement of the seal relative to the longitudinal axis during manipulation of the endoscopic instrument, wherein the flexible portion includes a bellow defined by a plurality of continuous bellows and characterised in that the plurality of continuous bellows include inner and outer continuous bellows. a main body; a seal adjacent the leading end, the seal capable of receiving an instrument therethrough while maintaining a substantial sealed relation with the instrument; and a flexible portion disposed between the main body and the seal, the flexible portion being configured to permit movement of the seal relative to the longitudinal axis during manipulation of the endoscopic instrument, wherein the flexible portion includes a bellow defined by a plurality of continuous bellows and characterised in that the plurality of continuous bellows include inner and outer continuous bellows.
A process for the preparation of crystalline form II of N -benzoyl-staurosporine comprising: (a) purifying staurosporine using a process comprising: (a') providing a suspension of staurosporine in an alcohol solvent; (b') contacting the suspension with methanesulfonic acid; (c') further contacting the solution with triethylamine; and (d') isolating the purified staurosporine; (b) reacting the purified staurosporine in an alcohol solvent with benzoic anhydride; (c) seeding the solution with crystalline form II of N -benzoyl-staurosporine; and (d) isolating the product which is crystalline form II of N -benzoyl-staurosporine. (a) purifying staurosporine using a process comprising: (a') providing a suspension of staurosporine in an alcohol solvent; (b') contacting the suspension with methanesulfonic acid; (c') further contacting the solution with triethylamine; and (d') isolating the purified staurosporine; (a') providing a suspension of staurosporine in an alcohol solvent; (b') contacting the suspension with methanesulfonic acid; (c') further contacting the solution with triethylamine; and (d') isolating the purified staurosporine; (b) reacting the purified staurosporine in an alcohol solvent with benzoic anhydride; (c) seeding the solution with crystalline form II of N -benzoyl-staurosporine; and (d) isolating the product which is crystalline form II of N -benzoyl-staurosporine.
An insulin polypeptide comprising a water soluble polymer linked by a covalent oxime bond to the insulin polypeptide A-chain at position 14 of the A-chain amino acid sequence selected from the group SEQ ID NO: 1, SEQ ID NO: 3, SEQ ID NO: 5, SEQ ID NO: 7, SEQ ID NO: 9, and SEQ ID NO: 11, wherein the amino acid at position 14 of the A-chain is a non-naturally encoded amino acid.
A user-replaceable e-liquid cartridge adapted to be inserted into or attached to a portable, personal storage and carrying case for an e-liquid e-cigarette PV and further adapted to engage with a fluid transfer system in the case.
A therapeutically effective amount of a pharmaceutically active agent selected from a bile acid, a bile salt, and a combination thereof; for use in the treatment in an individual of a metabolic disorder selected from obesity, diabetes, or a combination thereof, comprising non-systemically administering the pharmaceutically active agent to an individual in need thereof; characterized in that the pharmaceutically active agent is delivered to the colon or the rectum of said individual in need thereof.