A compound represented by the following structural formula: wherein X is R is NH 2 or OH; W is aryl or heteroaryl, optionally substituted with 1 to 3 substituents selected from R 7; Z is aryl or heteroaryl; L 1 is a bond; R 3 is 1) hydrogen, 2) unsubstituted or substituted C 1 -C 6 alkyl, 3) unsubstituted or substituted aryl, 4) unsubstituted or substituted heteroaryl 5) halo, 6) CN, 7) amide, 8) carboxyl, 9) C 1 -C 7 alkoxy, 10) C 1 -C 7 haloalkyl, 11) C 1 -C 7 haloalkyloxy, 12) C 1 -C 7 hydroxyalkyl, 13) C 1 -C 7 alkenyl, 14) C 1 -C 7 alkynyl, 15) C 1 -C 7 alkyl-C(=O)O-, 16) C 1 -C 7 alkyl-C(=O)-, 17) hydroxyalkoxy, 18) -NHO 2, 19) -SO 2 NH, 20) C 1 -C 7 alkyl-NHSO 2 -, 21) C 1 -C 7 alkyl-SO 2 NH-, 22) C 1 -C 7 alkylsulfonyl, 23) C 1 -C 7 alkylamino, 24) di(C 1 -C 7)alkylamino, or 25) L 2 -R 12; each R 7 is independently hydrogen, OH, NR 11 2, nitro, CN, amide, carboxyl, C 1 -C 7 alkoxy, C 1 -C 7 alkyl, C 1 -C 7 haloalkyl, C 1 -C 7 haloalkyloxy, C 1 -C 7 hydroxyalkyl, C 1 -C 7 alkenyl, C 1 -C 7 alkyl-C(=O)O-, C 1 -C 7 alkyl-C(=O)-, C 1 -C 7 alkynyl, halo group, amide, hydroxyalkoxy, -NR 11 SO 2,-SO 2 NR 11 2, C 1 -C 7 alkyl-NR 11 SO 2 -, C 1 -C 7 alkyl-SO 2 NR 11 -, C 1 -C 7 alkylsulfonyl, C 1 -C 7 alkylamino or di(C 1 -C 7)alkylamino; each R 11 is independently hydrogen, C 1 -C 6 alkyl, or aryl, wherein said alkyl and aryl groups are optionally substituted; L 2 is 1) a bond, 2) C 1 -C 4 alkylene, 3) C 1 -C 4 alkynyl, 4) C 1 -C 4 alkenyl, 5) -O-, 6) -S-, 7) -NH-, 8) -C(=O)NH-, 9) -NHC(=O)-, 10) -NHC(=O)NH-, 11) -SO 2 NH-, 12) -NHSO 2 -, 13) -SO 2 -, 14) -C(=O)- or 15) -C(=O)O-; R 12 is 1) substituted or unsubstituted heteroaryl, 2) substituted or unsubstituted heterocyclyl, 3) substituted or unsubstituted aryl, and 4) substituted or unsubstituted C 3 -C 8 cycloalkyl; q is 1, 2, 3, or 4; or a stereoisomer or a pharmaceutically acceptable salt thereof. wherein X is R is NH 2 or OH; W is aryl or heteroaryl, optionally substituted with 1 to 3 substituents selected from R 7; Z is aryl or heteroaryl; L 1 is a bond; R 3 is 1) hydrogen, 2) unsubstituted or substituted C 1 -C 6 alkyl, 3) unsubstituted or substituted aryl, 4) unsubstituted or substituted heteroaryl 5) halo, 6) CN, 7) amide, 8) carboxyl, 9) C 1 -C 7 alkoxy, 10) C 1 -C 7 haloalkyl, 11) C 1 -C 7 haloalkyloxy, 12) C 1 -C 7 hydroxyalkyl, 13) C 1 -C 7 alkenyl, 14) C 1 -C 7 alkynyl, 15) C 1 -C 7 alkyl-C(=O)O-, 16) C 1 -C 7 alkyl-C(=O)-, 17) hydroxyalkoxy, 18) -NHO 2, 19) -SO 2 NH, 20) C 1 -C 7 alkyl-NHSO 2 -, 21) C 1 -C 7 alkyl-SO 2 NH-, 22) C 1 -C 7 alkylsulfonyl, 23) C 1 -C 7 alkylamino, 24) di(C 1 -C 7)alkylamino, or 25) L 2 -R 12; 1) hydrogen, 2) unsubstituted or substituted C 1 -C 6 alkyl, 3) unsubstituted or substituted aryl, 4) unsubstituted or substituted heteroaryl 5) halo, 6) CN, 7) amide, 8) carboxyl, 9) C 1 -C 7 alkoxy, 10) C 1 -C 7 haloalkyl, 11) C 1 -C 7 haloalkyloxy, 12) C 1 -C 7 hydroxyalkyl, 13) C 1 -C 7 alkenyl, 14) C 1 -C 7 alkynyl, 15) C 1 -C 7 alkyl-C(=O)O-, 16) C 1 -C 7 alkyl-C(=O)-, 17) hydroxyalkoxy, 18) -NHO 2, 19) -SO 2 NH, 20) C 1 -C 7 alkyl-NHSO 2 -, 21) C 1 -C 7 alkyl-SO 2 NH-, 22) C 1 -C 7 alkylsulfonyl, 23) C 1 -C 7 alkylamino, 24) di(C 1 -C 7)alkylamino, or 25) L 2 -R 12; each R 7 is independently hydrogen, OH, NR 11 2, nitro, CN, amide, carboxyl, C 1 -C 7 alkoxy, C 1 -C 7 alkyl, C 1 -C 7 haloalkyl, C 1 -C 7 haloalkyloxy, C 1 -C 7 hydroxyalkyl, C 1 -C 7 alkenyl, C 1 -C 7 alkyl-C(=O)O-, C 1 -C 7 alkyl-C(=O)-, C 1 -C 7 alkynyl, halo group, amide, hydroxyalkoxy, -NR 11 SO 2,-SO 2 NR 11 2, C 1 -C 7 alkyl-NR 11 SO 2 -, C 1 -C 7 alkyl-SO 2 NR 11 -, C 1 -C 7 alkylsulfonyl, C 1 -C 7 alkylamino or di(C 1 -C 7)alkylamino; each R 11 is independently hydrogen, C 1 -C 6 alkyl, or aryl, wherein said alkyl and aryl groups are optionally substituted; L 2 is 1) a bond, 2) C 1 -C 4 alkylene, 3) C 1 -C 4 alkynyl, 4) C 1 -C 4 alkenyl, 5) -O-, 6) -S-, 7) -NH-, 8) -C(=O)NH-, 9) -NHC(=O)-, 10) -NHC(=O)NH-, 11) -SO 2 NH-, 12) -NHSO 2 -, 13) -SO 2 -, 14) -C(=O)- or 15) -C(=O)O-; 1) a bond, 2) C 1 -C 4 alkylene, 3) C 1 -C 4 alkynyl, 4) C 1 -C 4 alkenyl, 5) -O-, 6) -S-, 7) -NH-, 8) -C(=O)NH-, 9) -NHC(=O)-, 10) -NHC(=O)NH-, 11) -SO 2 NH-, 12) -NHSO 2 -, 13) -SO 2 -, 14) -C(=O)- or 15) -C(=O)O-; R 12 is 1) substituted or unsubstituted heteroaryl, 2) substituted or unsubstituted heterocyclyl, 3) substituted or unsubstituted aryl, and 4) substituted or unsubstituted C 3 -C 8 cycloalkyl; 1) substituted or unsubstituted heteroaryl, 2) substituted or unsubstituted heterocyclyl, 3) substituted or unsubstituted aryl, and 4) substituted or unsubstituted C 3 -C 8 cycloalkyl; q is 1, 2, 3, or 4;