mhurhangee/ep-ind-claims huggingface dataset:
An anti-human PD-1 monoclonal antibody, characterized in that the anti-human PD-1 monoclonal antibody comprises: a heavy chain complementarity determining region CDRH1, CDRH2, CDRH3, wherein the CDRH1 has the amino acid sequence as shown in SEQ ID NO: 1, the CDRH2 has the amino acid sequence as shown in SEQ ID NO: 2, and the CDRH3 has the amino acid sequence as shown in SEQ ID NO: 3, and a light chain complementarity determining region CDRL1, CDRL2, CDRL3, wherein the CDRL1 has the amino acid sequence as shown in SEQ ID NO: 4, the CDRL2 has the amino acid sequence as shown in SEQ ID NO: 5, and the CDRL3 has the amino acid sequence as shown in SEQ ID NO: 6; wherein the anti-human PD-1 monoclonal antibody comprises a heavy chain variable region having the amino acid sequence as shown in SEQ ID NO: 7, and a light chain variable region having the amino acid sequence as shown in SEQ ID NO: 9. a heavy chain complementarity determining region CDRH1, CDRH2, CDRH3, wherein the CDRH1 has the amino acid sequence as shown in SEQ ID NO: 1, the CDRH2 has the amino acid sequence as shown in SEQ ID NO: 2, and the CDRH3 has the amino acid sequence as shown in SEQ ID NO: 3, and a light chain complementarity determining region CDRL1, CDRL2, CDRL3, wherein the CDRL1 has the amino acid sequence as shown in SEQ ID NO: 4, the CDRL2 has the amino acid sequence as shown in SEQ ID NO: 5, and the CDRL3 has the amino acid sequence as shown in SEQ ID NO: 6;
A method comprising: obtaining a plurality of texture images of a scene, each texture image having a different respective focal distance; filtering each texture image of the plurality of texture images to form a corresponding defocus map for each texture image; for each texture image of the plurality of texture images and for each corresponding defocus map, generating a corresponding focal weight map from the defocus map, wherein each corresponding focal weight map comprises a plurality of focal weights representing an amount by which each respective pixel of a plurality of pixels of the corresponding texture image is in focus, the focal weights for the pixels in the texture image being determined based on the corresponding defocus map; and for each texture image of the plurality of texture images, generating a corresponding focal plane image by multiplying the texture image by the focal weight map, wherein multiplying the texture image by the focal weight map comprises multiplying a pixel value of each of the plurality of pixels of the texture image by the corresponding focal weight of the plurality of focal weights of the focal weight map. obtaining a plurality of texture images of a scene, each texture image having a different respective focal distance; filtering each texture image of the plurality of texture images to form a corresponding defocus map for each texture image; for each texture image of the plurality of texture images and for each corresponding defocus map, generating a corresponding focal weight map from the defocus map, wherein each corresponding focal weight map comprises a plurality of focal weights representing an amount by which each respective pixel of a plurality of pixels of the corresponding texture image is in focus, the focal weights for the pixels in the texture image being determined based on the corresponding defocus map; and for each texture image of the plurality of texture images, generating a corresponding focal plane image by multiplying the texture image by the focal weight map, wherein multiplying the texture image by the focal weight map comprises multiplying a pixel value of each of the plurality of pixels of the texture image by the corresponding focal weight of the plurality of focal weights of the focal weight map.
A plasma confinement tube for use in an induction plasma torch, the plasma confinement tube defining a geometrical axis and an outer surface, and comprising: a capacitive shield including a film of conductive material applied to the outer surface of the plasma confinement tube and segmented into axial strips (51, 51') interconnected at one end, characterised in that: axial grooves are formed in the outer surface of the plasma confinement tube, each one of the axial grooves being interposed between a pair of laterally adjacent axial strips (51, 51').
A Reaction Wheel Assembly system (10, 80, 130), comprising: a multi-faceted bracket structure (14, 82, 132) having a centerline (12, 84), RWA-support faces (18, 86, 136) angularly spaced about the centerline, and a vehicle mount interface (30, 94, 158) substantially orthogonal to the centerline; and a plurality of RWAs (16, 88, 138) containing a plurality of rotors (52, 144) and mounted to the RWA-support faces of the multi-faceted bracket structure; characterized in that: the multi-faceted bracket structure is assembled from multiple interchangeable panels (82, 134), each defining one of the RWA-support faces and a portion of the vehicle mount interface; the multiple interchangeable panels comprise mount brackets (20, 112) formed in the RWA-support faces, the plurality of rotors mounted to the mount brackets for rotation about a plurality of spin axes; and the multiple interchangeable panels further comprise mating interconnect features (102, 158), which align when the multi-faceted bracket structure is assembled to position the multiple interchangeable panels and the plurality of spin axes in a predetermined spatial relationship. a multi-faceted bracket structure (14, 82, 132) having a centerline (12, 84), RWA-support faces (18, 86, 136) angularly spaced about the centerline, and a vehicle mount interface (30, 94, 158) substantially orthogonal to the centerline; and a plurality of RWAs (16, 88, 138) containing a plurality of rotors (52, 144) and mounted to the RWA-support faces of the multi-faceted bracket structure; characterized in that: the multi-faceted bracket structure is assembled from multiple interchangeable panels (82, 134), each defining one of the RWA-support faces and a portion of the vehicle mount interface; the multiple interchangeable panels comprise mount brackets (20, 112) formed in the RWA-support faces, the plurality of rotors mounted to the mount brackets for rotation about a plurality of spin axes; and the multiple interchangeable panels further comprise mating interconnect features (102, 158), which align when the multi-faceted bracket structure is assembled to position the multiple interchangeable panels and the plurality of spin axes in a predetermined spatial relationship. the multi-faceted bracket structure is assembled from multiple interchangeable panels (82, 134), each defining one of the RWA-support faces and a portion of the vehicle mount interface; the multiple interchangeable panels comprise mount brackets (20, 112) formed in the RWA-support faces, the plurality of rotors mounted to the mount brackets for rotation about a plurality of spin axes; and the multiple interchangeable panels further comprise mating interconnect features (102, 158), which align when the multi-faceted bracket structure is assembled to position the multiple interchangeable panels and the plurality of spin axes in a predetermined spatial relationship.
A cosmetic composition comprising: (i) from about 0.01 to about 10% of single-crystal platy barium sulfate by weight of the composition; (ii) from about 0.1 to about 10% of a water-insoluble powdered acrylic polymer in porous particle form; and (iii) a cosmetically acceptable carrier, wherein the number average particle size of the single-crystal platy barium sulfate is from 8 to 15 microns. (i) from about 0.01 to about 10% of single-crystal platy barium sulfate by weight of the composition; (ii) from about 0.1 to about 10% of a water-insoluble powdered acrylic polymer in porous particle form; and (iii) a cosmetically acceptable carrier,
An ankle-foot orthosis element, comprising: - a base plate element, comprising a substantially flat front section, a middle section, a substantially flat rear section; - at least one supporting element (21, 22) supported by said base plate element; - a top section supported by said at least one supporting element (21, 22) and characterised in that said base plate element comprises a flexible concave shape at the middle section of said base plate element for fixating said ankle-foot orthosis element in a foot wear when flexed towards the foot wear. - a base plate element, comprising a substantially flat front section, a middle section, a substantially flat rear section; - at least one supporting element (21, 22) supported by said base plate element; - a top section supported by said at least one supporting element (21, 22) and characterised in that said base plate element comprises a flexible concave shape at the middle section of said base plate element for fixating said ankle-foot orthosis element in a foot wear when flexed towards the foot wear.
A method for recognizing scribble input, the method comprising: receiving an input via an input device in an electronic document; determining if the received input is scribble input based on a location of the received input being in a margin of the electronic document and a length of time associated with drawing the received input; and if the received input is scribble input, making a determination whether to erase the scribble input, wherein making the determination to erase the scribble input is based upon receiving input elsewhere in the electronic document or upon detecting a passing of a predetermined amount of time without receiving additional input after receiving the scribble input, and erasing the scribble input. receiving an input via an input device in an electronic document; determining if the received input is scribble input based on a location of the received input being in a margin of the electronic document and a length of time associated with drawing the received input; and if the received input is scribble input, making a determination whether to erase the scribble input, wherein making the determination to erase the scribble input is based upon receiving input elsewhere in the electronic document or upon detecting a passing of a predetermined amount of time without receiving additional input after receiving the scribble input, and erasing the scribble input.
Connection system for connecting a pipe to a main pipe, a shaft, or the like, at a transverse opening, the connection system being connectable for this purpose to the main pipe or the shaft, comprising a hollow stopper-shaped, at least partly soft installation insert, the outer side of which is adapted to the transverse opening and the inner side of which has a conical screw region, wherein the installation insert has an end section, which can be pushed partly into the main pipe or shaft through the transverse opening thereof, and wherein an outer bearing surface of the installation insert, in a connection state in which the connection system is connected to the main pipe or shaft, is at least partly in contact with a main pipe inner surface, which borders and surrounds the transverse opening, and a relatively harder connecting piece, which has an engagement end, a conical centre part with an external thread, and a drive end, characterised in that there is formed on the end section at least one separation indicator, which runs at least partly around the outer perimeter of the end section, the separation indicator being adapted to the shape of the inner surface of the main pipe, the shaft, or the like, in the region of the transverse opening. a hollow stopper-shaped, at least partly soft installation insert, the outer side of which is adapted to the transverse opening and the inner side of which has a conical screw region, wherein the installation insert has an end section, which can be pushed partly into the main pipe or shaft through the transverse opening thereof, and wherein an outer bearing surface of the installation insert, in a connection state in which the connection system is connected to the main pipe or shaft, is at least partly in contact with a main pipe inner surface, which borders and surrounds the transverse opening, and a relatively harder connecting piece, which has an engagement end, a conical centre part with an external thread, and a drive end, characterised in that there is formed on the end section at least one separation indicator, which runs at least partly around the outer perimeter of the end section, the separation indicator being adapted to the shape of the inner surface of the main pipe, the shaft, or the like, in the region of the transverse opening.
Planar drive system comprising at least two, preferably a plurality of, stator modules and a frame, wherein each of the stator modules comprises a main body having a transport surface and a rear side opposite the transport surface, and also a mounting plate detachably mounted on the rear side of the main body, wherein the frame has a plurality of receptacles, wherein each receptacle is designed to receive a stator module, wherein the stator modules can be inserted, with the transport surface forward, into the receptacles of the frame and can be locked in the receptacles by means of a locking mechanism. at least two, preferably a plurality of, stator modules and a frame, wherein each of the stator modules comprises a main body having a transport surface and a rear side opposite the transport surface, and also a mounting plate detachably mounted on the rear side of the main body, wherein the frame has a plurality of receptacles, wherein each receptacle is designed to receive a stator module, wherein the stator modules can be inserted, with the transport surface forward, into the receptacles of the frame and can be locked in the receptacles by means of a locking mechanism.
An mRNA molecule having a coding region and optionally, one or more non-coding regions, wherein at least 1% of the nucleotide residues of the mRNA incorporate a 4'-thio-substituted furanose ring, wherein the modified mRNA has an improved stability and translational efficiency when compared to the non-modified mRNA.
Multi-component kit for a curable composition for fixing purposes, comprising an epoxy resin component (a), which comprises curable epoxides, and a hardener component (b), which comprises a Mannich base formulation, characterized in that the Mannich base formulation has H equivalents in the range from 40 to 80, a viscosity in the range from 500 to 2700 mPa.s when measured with a Brookfield rotary viscometer using spindle 3 at 23°C at from 10 to 50 rev/min, and a content of free phenol derivatives of 20 % by weight or less.
A map creation method of a mobile robot, the mobile robot working indoors comprising the following steps: S1: obtaining Euler angles of a current point relative to a reference point according to ceiling images obtained at the current point and the reference point; S2: determining whether a roll angle θ y of the Euler angles is lower than a preset value, saving map data of the current point if the roll angle of the Euler angles is lower than the preset value, and not saving the map data of the current point if the roll angle of the Euler angles is not lower than the preset value; S3: returning to step S1 after the mobile robot moves a predetermined distance or for a predetermined time; and S4: repeating steps S1 through S3 until the map creation in a working area is complete, wherein the current point is the current position of the mobile robot, and the reference point is the position where the mobile robot saves the map data. S1: obtaining Euler angles of a current point relative to a reference point according to ceiling images obtained at the current point and the reference point; S2: determining whether a roll angle θ y of the Euler angles is lower than a preset value, saving map data of the current point if the roll angle of the Euler angles is lower than the preset value, and not saving the map data of the current point if the roll angle of the Euler angles is not lower than the preset value; S3: returning to step S1 after the mobile robot moves a predetermined distance or for a predetermined time; and S4: repeating steps S1 through S3 until the map creation in a working area is complete, wherein the current point is the current position of the mobile robot, and the reference point is the position where the mobile robot saves the map data.
A low dose pharmaceutical composition comprising [(2-hydroxy-4-oxo-6,7,8,9-tetrahydro-4H,5H-10-thia-1,4a-diaza-benzo[a]azulene-3-carbonyl)-amino]-acetic acid or its pharmaceutically acceptable salt in an amount of 2.5 mg to 60 mg and at least one pharmaceutically acceptable carrier selected from diluent, binder, disintegrant, pH adjusting agent and lubricant, for use in treating inflammatory bowel disease.
A microprocessor having an instruction set architecture that defines a conditional load instruction that specifies a register or shifted register offset source and that specifies a non-immediate offset source and a pre-indexed or offset-addressed addressing mode, the microprocessor characterised by: a register file; an instruction translator that is configured to translate (1124, 1126, 1134, 1136) the conditional load instruction into at least two microinstructions, wherein the conditional load instruction specifies a destination register and source registers of the register file; and an out-of-order execution pipeline, comprising a plurality of execution units that execute the microinstructions; wherein one of the execution units is configured to execute a first of the microinstructions by receiving source operands from the source registers of the register file, the source operands comprising a base address and an offset, and in response generating a first result using the source operands, the first result comprising a sum of the base address and the offset; wherein one of the execution units is configured to execute a second of the microinstructions by receiving a previous value of the destination register and the first result, and in response reading data from a memory location specified by the first result and providing a second result that is the data if a condition is satisfied and that is the previous destination register value if not; wherein the previous value of the destination register comprises a result produced by execution of a microinstruction that is the most recent in-order previous writer of the destination register with respect to the second microinstruction. a register file; an instruction translator that is configured to translate (1124, 1126, 1134, 1136) the conditional load instruction into at least two microinstructions, wherein the conditional load instruction specifies a destination register and source registers of the register file; and an out-of-order execution pipeline, comprising a plurality of execution units that execute the microinstructions; wherein one of the execution units is configured to execute a first of the microinstructions by receiving source operands from the source registers of the register file, the source operands comprising a base address and an offset, and in response generating a first result using the source operands, the first result comprising a sum of the base address and the offset; wherein one of the execution units is configured to execute a second of the microinstructions by receiving a previous value of the destination register and the first result, and in response reading data from a memory location specified by the first result and providing a second result that is the data if a condition is satisfied and that is the previous destination register value if not; wherein the previous value of the destination register comprises a result produced by execution of a microinstruction that is the most recent in-order previous writer of the destination register with respect to the second microinstruction.
A method of producing a modified biomass composition having a high heating value, comprising the steps of - providing biomass containing cellulose, lignin and hemicelluloses; - subjecting the biomass to a step of hot water extraction at a pre-determined temperature in excess of 100 °C; - continuing the hot water extraction so as to remove at least 50 weight-% of hemicelluloses and less than 10 weight-% of lignin from the biomass so as to produce an extracted biomass; - recovering the extracted biomass; and - subjecting the warm, extracted biomass to press-drying so as to achieve a biomass having dry matter content which is higher than 50 weight-%, wherein the biomass comprises wood. - providing biomass containing cellulose, lignin and hemicelluloses; - subjecting the biomass to a step of hot water extraction at a pre-determined temperature in excess of 100 °C; - continuing the hot water extraction so as to remove at least 50 weight-% of hemicelluloses and less than 10 weight-% of lignin from the biomass so as to produce an extracted biomass; - recovering the extracted biomass; and - subjecting the warm, extracted biomass to press-drying so as to achieve a biomass having dry matter content which is higher than 50 weight-%,
A windscreen wiper device of the flat blade type, particularly for automobiles, comprising an elastic, elongated carrier element, as well as an elongated wiper blade of a flexible material, which can be placed in abutment with a windscreen to be wiped, which wiper blade includes at least one longitudinal groove, in which groove at least one longitudinal strip of the carrier element is disposed, which windscreen wiper device comprises a connecting device for an oscillating arm, wherein said oscillating arm can be pivotally connected to said connecting device about a pivot axis near one end thereof, wherein said connecting device is connected to the flexible material of said wiper blade by at least one pin, wherein said pin cooperates with a recess provided along an exterior edge of said longitudinal strip in order to block any movement of said wiper blade in longitudinal direction thereof relative to said longitudinal strip at the location of the interconnection of said connecting device and said wiper blade, wherein said connecting device is connected to the flexible material of said wiper blade by said at least one pin being of a first type and at least one pin of a second type, wherein said pin of the second type is slightly deforming said wiper blade at the location of the interconnection of said connecting device and said wiper blade in order to block any lateral movement of longitudinal strip at the location of the interconnection of said connecting device and said wiper blade, characterized in that said pin of the first type and said pin of the second type are separate constructional elements extending at least substantially perpendicular to the windscreen to be wiped.