A sealed atomic force microscope cell for an AFM which measures a sample immersed in an observation liquid, the sealed AFM cell comprising: a cantilever including a probe; a sample holder for fixing the sample; a scanner which is a drive unit configured to move the sample holder; a lid part (122; 122A; 122B) which holds the cantilever so as to position the probe near a measurement surface of the sample; a main body part (136; 136A) which is a body component for holding the scanner and positioned opposite the lid part (122; 122A; 122B) with the sample in between; two components (172A, 172B) provided to at least one of the lid part (122; 122A; 122B) and the main body part (136; 136A), the two components (172A, 172B) having water repellency or oil repellency; and a sealing liquid held by the two components (172A, 172B), the sealing liquid being different from the observation liquid and not in contact with the observation liquid, and the water repellency or oil repellency of the two components (172A, 172B) with the sealing liquid being enough so that a contact angle represented by a droplet of the sealing liquid represents at least 10 degrees on the surfaces of the two components (172A, 172B); wherein the lid part (122; 122A; 122B) and the main body part (136; 136A) are joined together via the sealing liquid, wherein the observation liquid is sealed inside a space formed by the lid part (122; 122A; 122B), the main body part (136; 136A), and the sealing liquid, wherein at least one of the lid part (122; 122A; 122B) and the main body part (136; 136A) has a wall protruding from one of the lid part (122; 122A; 122B) and the main body part (136; 136A) toward the other of the lid part (122; 122A; 122B) and the main body part (136; 136A) to surround the sample holder, wherein the two components (172A, 172B) are provided on an end portion of the wall, wherein at least one of the lid part (122; 122A; 122B) and the main body part (136; 136A) has a groove, wherein the groove is formed by the two components (172A, 172B) and by the at least one of the lid part (122; 122A; 122B) and the main body part (136; 136A) which the sealing component is on, and wherein the groove holds the sealing liquid. a cantilever including a probe; a sample holder for fixing the sample; a scanner which is a drive unit configured to move the sample holder; a lid part (122; 122A; 122B) which holds the cantilever so as to position the probe near a measurement surface of the sample; a main body part (136; 136A) which is a body component for holding the scanner and positioned opposite the lid part (122; 122A; 122B) with the sample in between; two components (172A, 172B) provided to at least one of the lid part (122; 122A; 122B) and the main body part (136; 136A), the two components (172A, 172B) having water repellency or oil repellency; and a sealing liquid held by the two components (172A, 172B), the sealing liquid being different from the observation liquid and not in contact with the observation liquid, and the water repellency or oil repellency of the two components (172A, 172B) with the sealing liquid being enough so that a contact angle represented by a droplet of the sealing liquid represents at least 10 degrees on the surfaces of the two components (172A, 172B); wherein the lid part (122; 122A; 122B) and the main body part (136; 136A) are joined together via the sealing liquid, wherein the observation liquid is sealed inside a space formed by the lid part (122; 122A; 122B), the main body part (136; 136A), and the sealing liquid, wherein at least one of the lid part (122; 122A; 122B) and the main body part (136; 136A) has a wall protruding from one of the lid part (122; 122A; 122B) and the main body part (136; 136A) toward the other of the lid part (122; 122A; 122B) and the main body part (136; 136A) to surround the sample holder, wherein the two components (172A, 172B) are provided on an end portion of the wall, wherein at least one of the lid part (122; 122A; 122B) and the main body part (136; 136A) has a groove, wherein the groove is formed by the two components (172A, 172B) and by the at least one of the lid part (122; 122A; 122B) and the main body part (136; 136A) which the sealing component is on, and wherein the groove holds the sealing liquid.