An implant insertion assembly, comprising: an insertion handle extending from a proximal end to a distal end, the distal end including a recessed portion, an outer wall of the recessed portion having a first shape about a perimeter thereof and including an engagement mechanism, wherein the engagement mechanism is an increased thickness flange; and an implant extending from a distal end to a proximal end including an opening configured to receive the recessed portion of the insertion handle, the opening having a second shape configured to mechanically interlock with the outer wall of the recessed portion when the recessed portion is inserted therein to transmit torque from the insertion handle to the implant, the proximal end including a receiving structure in a wall thereof, the receiving structure being a transverse cavity sized to receive the flange, the receiving structure being positioned and oriented to receive the engagement mechanism to removably lock the insertion handle to the implant in the axial direction wherein the insertion handle further comprises a pair of longitudinal slots extending through a wall of the insertion handle from an outer surface to an inner surface thereof, the slots defining a flexible beam therebetween configured to radially deflect within a predetermined range of motion when inserted into the implant, wherein the first shape is substantially hexalobular comprising six radially outwardly extending protrusions and six radially inwardly extending grooves alternating about the circumference of the recessed portion, wherein one of the protrusions comprises the flexible beam, and wherein the second shape is substantially hexalobular comprising five radially outwardly extending grooves and six radially inwardly extending protrusions alternating about a circumference of the opening, two of the protrusions being separated by a substantially flat portion configured to engage the flexible beam, and wherein the flexible beam is substantially rectangular along a plane perpendicular to the longitudinal axis of the insertion handle so that the recessed portion is insertable into the opening only when the flexible beam is aligned with the flat portion. an insertion handle extending from a proximal end to a distal end, the distal end including a recessed portion, an outer wall of the recessed portion having a first shape about a perimeter thereof and including an engagement mechanism, wherein the engagement mechanism is an increased thickness flange; and an implant extending from a distal end to a proximal end including an opening configured to receive the recessed portion of the insertion handle, the opening having a second shape configured to mechanically interlock with the outer wall of the recessed portion when the recessed portion is inserted therein to transmit torque from the insertion handle to the implant, the proximal end including a receiving structure in a wall thereof, the receiving structure being a transverse cavity sized to receive the flange, the receiving structure being positioned and oriented to receive the engagement mechanism to removably lock the insertion handle to the implant in the axial direction wherein the insertion handle further comprises a pair of longitudinal slots extending through a wall of the insertion handle from an outer surface to an inner surface thereof, the slots defining a flexible beam therebetween configured to radially deflect within a predetermined range of motion when inserted into the implant, wherein the first shape is substantially hexalobular comprising six radially outwardly extending protrusions and six radially inwardly extending grooves alternating about the circumference of the recessed portion, wherein one of the protrusions comprises the flexible beam, and wherein the second shape is substantially hexalobular comprising five radially outwardly extending grooves and six radially inwardly extending protrusions alternating about a circumference of the opening, two of the protrusions being separated by a substantially flat portion configured to engage the flexible beam, and wherein the flexible beam is substantially rectangular along a plane perpendicular to the longitudinal axis of the insertion handle so that the recessed portion is insertable into the opening only when the flexible beam is aligned with the flat portion.