mhurhangee/ep-ind-claims huggingface dataset:
A low-weight sound-absorbing dash pad for a vehicle, comprising: a sound-absorbing member made of microfibers, and a sound-absorbing/blocking multilayer bonded to a surface of the sound-absorbing member, wherein the sound-absorbing/blocking multilayer including a first sound-absorbing layer, a sound-blocking layer, and a second sound-absorbing layer that are made of thermoplastic resin and are sequentially bonded, characterized in that the first sound-absorbing layer is made of polyethylene terephthalate, PET, the sound-blocking layer is made of at least one of olefin-based resin and olefin-based thermoplastic elastomer, TPE, the second sound-absorbing layer is made of polyethylene terephthalate, PET, and the sound-blocking layer is provided between the first and second sound-absorbing layer (11,12), wherein the microfibers are obtained by twisting melt-blown polypropylene fibers and polypropylene staple fibers together in 100 to 1000 g/m 3, wherein the sound-absorbing/blocking multilayer has opposing first and second major surfaces, and gas transmission in a direction from the first major surface to the second major surface of the sound-absorbing/blocking multilayer is 0.1 to 30 cm 3 /cm 2 sec. a sound-absorbing member made of microfibers, and a sound-absorbing/blocking multilayer bonded to a surface of the sound-absorbing member, wherein the sound-absorbing/blocking multilayer including a first sound-absorbing layer, a sound-blocking layer, and a second sound-absorbing layer that are made of thermoplastic resin and are sequentially bonded, characterized in that the first sound-absorbing layer is made of polyethylene terephthalate, PET, the sound-blocking layer is made of at least one of olefin-based resin and olefin-based thermoplastic elastomer, TPE, the second sound-absorbing layer is made of polyethylene terephthalate, PET, and the sound-blocking layer is provided between the first and second sound-absorbing layer (11,12), wherein the microfibers are obtained by twisting melt-blown polypropylene fibers and polypropylene staple fibers together in 100 to 1000 g/m 3, wherein the sound-absorbing/blocking multilayer has opposing first and second major surfaces, and gas transmission in a direction from the first major surface to the second major surface of the sound-absorbing/blocking multilayer is 0.1 to 30 cm 3 /cm 2 sec.
Metal complex containing at least one partially fluorinated or perfluorinated ligand of the following structure wherein R 1 = R 2 = oxygen and wherein the ligand is a substituted or unsubstituted benzoic acid, characterized in that the metal is selected from the group containing bismuth, tin or mixtures thereof.
A method of editing one or more target genomic regions, comprising: administering to one or more cells that comprise one or more target genomic regions, a genome editing system and a compound represented by Structural Formula or Structural Formula (I'): or a pharmaceutically acceptable salt or a co-crystal thereof, wherein X is N, CR A5; R A1 is F, C 1-4 alkyl, C 3-5 cycloalkyl, OC 1-4 alkyl, OC 1-4 alkyl-C 3-5 cycloalkyl, NH 2, NHC 1-4 alkyl, NHC 1-4 alkyl-C 3-5 Cycloalkyl, or C 0-4 alkyl-heterocyclyl, wherein said heterocyclic ring system is selected from oxetanyl, tetrahydrofuranyl, tetrahydropyranyl, or morpholinyl, and each of said alkyl, cycloalkyl, or heterocyclyl is optionally substituted with up to three F atoms, up to three 2 H atoms, up to two non-geminal OH groups, or up to two OC 1-2 alkyl; each R A4 is, independently, H or 2 H; R A5 is hydrogen, F, C 1-4 alkyl, or OC 1-4 alkyl, wherein each of said alkyl is optionally substituted with up to three F atoms or up to three 2 H atoms; R B3 is C NHC 1-4 alkyl, wherein said alkyl is optionally substituted with up to three F atoms, up to three 2 H atoms, up to two non-geminal OH groups, or up to two OC 1 - 2 alkyl; and each R B4 is, independently, hydrogen, deuterium, F, or C 1-4 alkyl; and wherein the one or more target genomic regions are edited, optionally wherein the efficiency of editing the target genomic regions in the one or more cells is increased as compared to that in otherwise identical cell or cells but without the compound; and wherein the one or more cells are cultured cells or ex vivo cells from an organism. administering to one or more cells that comprise one or more target genomic regions, a genome editing system and a compound represented by Structural Formula or Structural Formula (I'): or a pharmaceutically acceptable salt or a co-crystal thereof, wherein X is N, CR A5; R A1 is F, C 1-4 alkyl, C 3-5 cycloalkyl, OC 1-4 alkyl, OC 1-4 alkyl-C 3-5 cycloalkyl, NH 2, NHC 1-4 alkyl, NHC 1-4 alkyl-C 3-5 Cycloalkyl, or C 0-4 alkyl-heterocyclyl, wherein said heterocyclic ring system is selected from oxetanyl, tetrahydrofuranyl, tetrahydropyranyl, or morpholinyl, and each of said alkyl, cycloalkyl, or heterocyclyl is optionally substituted with up to three F atoms, up to three 2 H atoms, up to two non-geminal OH groups, or up to two OC 1-2 alkyl; each R A4 is, independently, H or 2 H; R A5 is hydrogen, F, C 1-4 alkyl, or OC 1-4 alkyl, wherein each of said alkyl is optionally substituted with up to three F atoms or up to three 2 H atoms; R B3 is C NHC 1-4 alkyl, wherein said alkyl is optionally substituted with up to three F atoms, up to three 2 H atoms, up to two non-geminal OH groups, or up to two OC 1 - 2 alkyl; and each R B4 is, independently, hydrogen, deuterium, F, or C 1-4 alkyl; and wherein the one or more target genomic regions are edited, optionally wherein the efficiency of editing the target genomic regions in the one or more cells is increased as compared to that in otherwise identical cell or cells but without the compound; and wherein the one or more cells are cultured cells or ex vivo cells from an organism.
A bevacizumab antibody or biosimilar thereof and albumin-bound chemotherapeutic/bevacizumab antibody or biosimilar thereof nanoparticle complexes for use in a method of treating cancer which expresses vascular endothelial growth factor (VEGF) in a patient, wherein said patient is treated with a sub-therapeutic amount of the bevacizumab antibody or biosimilar thereof and the albumin-bound chemotherapeutic/ bevacizumab antibody or biosimilar thereof nanoparticle complexes containing a therapeutically effective amount of the chemotherapeutic such that the administration of said sub-therapeutic amount of the bevacizumab antibody or biosimilar thereof enhances the efficacy of said nanoparticle complexes, wherein the sub-therapeutic amount of bevacizumab antibody or biosimilar thereof is administered from between about 30 minutes to about 48 hours prior to administration of the albumin-bound chemotherapeutic/ bevacizumab antibody or biosimilar thereof nanoparticle complexes, wherein a therapeutic dosage of the bevacizumab antibody or biosimilar thereof is 5 mg/kg to 15 mg/kg; and wherein the sub-therapeutic amount of bevacizumab antibody or biosimilar thereof is selected from an amount consisting of 1%, 5%, 10%, 15%, 20%, 25% or 30% of the therapeutic dosage of bevacizumab antibody or biosimilar thereof. wherein said patient is treated with a sub-therapeutic amount of the bevacizumab antibody or biosimilar thereof and the albumin-bound chemotherapeutic/ bevacizumab antibody or biosimilar thereof nanoparticle complexes containing a therapeutically effective amount of the chemotherapeutic such that the administration of said sub-therapeutic amount of the bevacizumab antibody or biosimilar thereof enhances the efficacy of said nanoparticle complexes, wherein the sub-therapeutic amount of bevacizumab antibody or biosimilar thereof is administered from between about 30 minutes to about 48 hours prior to administration of the albumin-bound chemotherapeutic/ bevacizumab antibody or biosimilar thereof nanoparticle complexes, wherein a therapeutic dosage of the bevacizumab antibody or biosimilar thereof is 5 mg/kg to 15 mg/kg; and wherein the sub-therapeutic amount of bevacizumab antibody or biosimilar thereof is selected from an amount consisting of 1%, 5%, 10%, 15%, 20%, 25% or 30% of the therapeutic dosage of bevacizumab antibody or biosimilar thereof.
Walking skates system adapted to be removably coupled underneath a bottom half-ring of an external ring fixation system, said walking skates system comprising a pair of skates, each skate of said pair of skates having a curved bottom profile from which a protruding connection body provided with at least one slot (3a, 3b) projects, wherein said walking skates system further comprises a connecting member having a first end configured to be connected to an opening in the bottom half-ring of the external ring fixation system and a second end provided with a hole for connection to said slot (3a, 3b) in the connection body of the skate.
A heat transfer system comprising: a plenum configured to provide feedwater to a plurality of heat transfer tubes (71, 72, 73); a tube sheet configured to couple the plurality of heat transfer tubes (71, 72, 73) to the plenum; an orifice plate mounted within the plenum and located adjacent to the tube sheet; and one or more orifice devices (101, 102, 103) supported by the orifice plate and configured for insertion into the plurality of heat transfer tubes (71, 72, 73), wherein the one or more orifice devices (101, 102, 103) comprise helical shaped transition steps; characterized in that the heat transfer system further comprises means for an insertion of the helical shaped transition steps into the plurality of heat transfer tubes (71, 72, 73), wherein the means for an insertion are configured for determining a corresponding pressure drop of the feedwater in the heat transfer system. a plenum configured to provide feedwater to a plurality of heat transfer tubes (71, 72, 73); a tube sheet configured to couple the plurality of heat transfer tubes (71, 72, 73) to the plenum; an orifice plate mounted within the plenum and located adjacent to the tube sheet; and one or more orifice devices (101, 102, 103) supported by the orifice plate and configured for insertion into the plurality of heat transfer tubes (71, 72, 73), wherein the one or more orifice devices (101, 102, 103) comprise helical shaped transition steps;
A method within a Long Term Evolution communications network for calculating a random access transmission power to be used of a first communication device, the method comprising the steps of: - receiving data from a second communication device on a radio channel indicating a random access required target receive power, characterized in that the method further comprising: - determining a desired random access reception power level of the second communication device based on the received data and a parameter of random access configuration that influences a detection performance of the random access at the second communication device, which parameter comprises a preamble format signalled to the first communication device from the second communication device, and - calculating the random access transmission power to be used based on the desired random access reception power level and a power ramping increasing the random access transmission power based on a transmission attempt number, and also taking into account power path loss between the first communication device and the second communication device, and - performing a random access using the random access transmission power. - receiving data from a second communication device on a radio channel indicating a random access required target receive power, - determining a desired random access reception power level of the second communication device based on the received data and a parameter of random access configuration that influences a detection performance of the random access at the second communication device, which parameter comprises a preamble format signalled to the first communication device from the second communication device, and - calculating the random access transmission power to be used based on the desired random access reception power level and a power ramping increasing the random access transmission power based on a transmission attempt number, and also taking into account power path loss between the first communication device and the second communication device, and - performing a random access using the random access transmission power.
A method of controlling a drive comprising a power converter comprising one respective inverter associated with each of a plurality of servomotors in a robot, the power converter being located externally of the robot, the method comprising: providing a Pulse-Width Modulation, PWM, frequency corresponding to a frequency of switching instances for respective semiconductor switches in each of the inverters, whereby for each inverter time is divided into consecutive control cycles forming a control cycle sequence of the inverter, each control cycle containing two, and only two, of the switching instances for each of the semiconductor switches; spreading the respective control cycle sequences of the inverters over time such that the control cycle sequence of each inverter is time shifted in respect to the control cycle sequence of each of the other inverters in the power converter; sending firing pulses to the semiconductor switches in each of the inverters in accordance with the spread control cycles; and from each of the inverters, outputting an alternating current having an electrical frequency formed by the inverter in response to the sent firing pulses, to the servomotor associated with the inverter via an electrical connection having a length of at least 10 metres; wherein the provided PWM frequency is set dynamically based on a present highest motor speed of any of the servomotors, whereby the PWM frequency is reduced when none of the servomotors is running at maximum speed. providing a Pulse-Width Modulation, PWM, frequency corresponding to a frequency of switching instances for respective semiconductor switches in each of the inverters, whereby for each inverter time is divided into consecutive control cycles forming a control cycle sequence of the inverter, each control cycle containing two, and only two, of the switching instances for each of the semiconductor switches; spreading the respective control cycle sequences of the inverters over time such that the control cycle sequence of each inverter is time shifted in respect to the control cycle sequence of each of the other inverters in the power converter; sending firing pulses to the semiconductor switches in each of the inverters in accordance with the spread control cycles; and from each of the inverters, outputting an alternating current having an electrical frequency formed by the inverter in response to the sent firing pulses, to the servomotor associated with the inverter via an electrical connection having a length of at least 10 metres; wherein the provided PWM frequency is set dynamically based on a present highest motor speed of any of the servomotors, whereby the PWM frequency is reduced when none of the servomotors is running at maximum speed.
Plunger coil, comprising a coil with an air gap, a threaded spindle which penetrates the air gap and has a cylindrical base body made of metal, and a plunger (6, 6') with a screw nut (9, 9') wound onto the threaded spindle, said screw nut resting on the side of the plunger (6, 6') facing the air gap, characterised in that at least one longitudinal section (15, 16) of the base body of the threaded spindle is provided with at least one slot which extends across the longitudinal section (15, 16), said slot being filled with a non-metallic insert, wherein an outer surface of the insert forms a thread (10, 10') with an outer surface of the base body across the longitudinal section (15, 16).
A safety head assembly, comprising: an inlet safety head comprising: a body having an inner bore defining a fluid flow path, the body also having a circular flange portion; and inlet safety head projections projecting outwardly from the body of the inlet safety head, each inlet safety head projection having a face exhibiting a blended radius of curvature; an outlet safety head comprising: a body having an inner bore defining a fluid flow path, the body also having a circular flange portion; and outlet safety head projections projecting outwardly from the body of the outlet safety head, each outlet safety head projection having a face exhibiting a blended radius of curvature; wherein the flange portion of the inlet safety head and the flange portion of the outlet safety head are configured to receive an insert device placed between them; wherein a straight edge runs between each projection, the straight edge running tangentially to the circular flange. an inlet safety head comprising: a body having an inner bore defining a fluid flow path, the body also having a circular flange portion; and inlet safety head projections projecting outwardly from the body of the inlet safety head, each inlet safety head projection having a face exhibiting a blended radius of curvature; a body having an inner bore defining a fluid flow path, the body also having a circular flange portion; and inlet safety head projections projecting outwardly from the body of the inlet safety head, each inlet safety head projection having a face exhibiting a blended radius of curvature; an outlet safety head comprising: a body having an inner bore defining a fluid flow path, the body also having a circular flange portion; and outlet safety head projections projecting outwardly from the body of the outlet safety head, each outlet safety head projection having a face exhibiting a blended radius of curvature; a body having an inner bore defining a fluid flow path, the body also having a circular flange portion; and outlet safety head projections projecting outwardly from the body of the outlet safety head, each outlet safety head projection having a face exhibiting a blended radius of curvature; wherein the flange portion of the inlet safety head and the flange portion of the outlet safety head are configured to receive an insert device placed between them; wherein a straight edge runs between each projection, the straight edge running tangentially to the circular flange.
A method for assuring that a computing device meets preselected requirements to be validated by a policy enforcing network access point before allowing the computing device to access an external network, said validation characterized by the policy enforcing network access point: receiving from the computing device a proof (M 8.10) of establishing satisfaction of external accessibility requirements set by the policy enforcing network access point, where the external accessibility requirements (622, 213) include requiring execution of an authorized access payload, the authorized access payload comprising at least one of means to provide access to encrypted communications of the computing device and means to provide for simplifying the unlocking of the computing device without knowledge of any user password, and verification of the authorization of the access payload uses a value unique to said computer device; and checking validity (A 8.11) of the proof (M 8.10). receiving from the computing device a proof (M 8.10) of establishing satisfaction of external accessibility requirements set by the policy enforcing network access point, where the external accessibility requirements (622, 213) include requiring execution of an authorized access payload, the authorized access payload comprising at least one of means to provide access to encrypted communications of the computing device and means to provide for simplifying the unlocking of the computing device without knowledge of any user password, and verification of the authorization of the access payload uses a value unique to said computer device; and checking validity (A 8.11) of the proof (M 8.10).
In combination, a subsea well head, a plurality of casing strings and a modified casing coupling housing a pressure relief valve, the subsea well head being connectable by a subsea conduit to a floating work station, the subsea well head being connected to said plurality of casing strings for being located in a borehole below the subsea well head and defining at least one casing annulus therebetween, wherein the modified casing coupling is located within at last least one of the plurality of casing strings; the modified casing coupling having a sidewall having interior and exterior sidewalls (138, 140) which define an interior and an exterior of the coupling, and wherein the pressure relief valve has a valve body housed in the sidewall of said modified casing coupling so that no protuberance is created in the outer diameter of the casing string in which the modified casing coupling is located, wherein the modified casing coupling has a threaded opening provided in the sidewall, and the valve body is threaded within said threaded opening, and wherein the pressure relief valve has a through bore with opposing end openings (144, 146), the through bore communicating with the interior of the modified casing coupling at one end opening thereof and with an area surrounding the modified casing coupling at an opposite end opening thereof, wherein the through bore includes a ball seat adjacent one end opening thereof which receives a sealing ball, and wherein the ball is urged in the direction of the ball seat by a tensioning element located within the through bore which exerts a given amount of tension on the ball; and wherein the ball is exposed to annular pressure trapped between successive lengths of well casing located in the well borehole and wherein the amount of tension exerted on the ball by the tensioning element is selected to allow the ball to move off the ball seat and to thereby release trapped annular pressure between the selected casing strings once a predetermined annulus pressure is reached.
Control valve for adjusting a process medium flow of a technical process installation, comprising a housing with an interior to be traversed by the process medium, a valve seat disposed inside the housing interior, a valve member obstructing or clearing the valve seat, wherein a flow cross section of the control valve can be altered according to the relative position between the valve member and the valve seat for adjusting the process medium flow in order to initiate a pressure change in the process medium flow between the upstream and the downstream duct section (21, 23), and an electrical consumer like a sensor, a positioner, a sender, an accumulator, wherein additionally a thermoelectric element is disposed in the housing interior which thermoelectric element is coupled to the electrical consumer for supplying electric power and generates electric power, to be conducted to the consumer, at the location of the disposal of the thermoelectric element owing to a temperature difference that accompanies pressure difference, wherein the thermoelectric element is disposed at an outside of the valve member and/or at an inside of the valve seat.