mhurhangee/ep-ind-claims huggingface dataset:
Filter device for gases, particularly an air filtering device, preferably for a fresh air apparatus of an internal combustion engine, for example in a motor car, - having a housing which comprises at least a first housing part and a second housing part which axially abut one another in a flange region, - having a plate-shaped filter element comprising a circumferential seal which engages in the flange region, - the first housing part comprising, in the flange region, two radial bearing surfaces (15, 16) located opposite one another, - the seal having two radial sealing surfaces (17, 18) facing away from each other which lie flat against the bearing surfaces (15, 16), characterised in that - the seal comprises, radially between the sealing surfaces (17, 18), a circumferentially extending slotted region which is axially open towards the second housing part, - a plurality of radial webs spaced apart from one another in the circumferential direction, by means of which radially opposing slotted walls (40, 41) are radially supported on one another, are provided in the slotted region. - having a housing which comprises at least a first housing part and a second housing part which axially abut one another in a flange region, - having a plate-shaped filter element comprising a circumferential seal which engages in the flange region, - the first housing part comprising, in the flange region, two radial bearing surfaces (15, 16) located opposite one another, - the seal having two radial sealing surfaces (17, 18) facing away from each other which lie flat against the bearing surfaces (15, 16), - the seal comprises, radially between the sealing surfaces (17, 18), a circumferentially extending slotted region which is axially open towards the second housing part, - a plurality of radial webs spaced apart from one another in the circumferential direction, by means of which radially opposing slotted walls (40, 41) are radially supported on one another, are provided in the slotted region.
A method for centering and temporary fixation of tube parts relative to each other before a joint welding operation of the tube parts to each other, where a first tube part comprises a first interior surface, a first exterior surface and a first tube part end, and a second tube part comprises a second interior surface, a second exterior surface and a second tube part end, characterized by the following steps: a. a first tool is centered relative to the interior surface of the first tube part, b. a second tool is centered in relation to the first tool, c. with the second tool is the first tube part fixed at its exterior surface, whereby said tube part thereby is fixed and centered relative to the second tool, d. the first tool is removed from the first tube part, e. the steps a-d are repeated in the same way for the second tube part, f. both second tools, arranged at respective first and second tube part (1, 5), are centered relative to each other and are connected, whereby the tube parts (1, 5) will be centered relative to each other with respect to the interior surfaces (2, 6), and further fixed with a predetermined distance between respective tube part end (4, 8). a. a first tool is centered relative to the interior surface of the first tube part, b. a second tool is centered in relation to the first tool, c. with the second tool is the first tube part fixed at its exterior surface, whereby said tube part thereby is fixed and centered relative to the second tool, d. the first tool is removed from the first tube part, e. the steps a-d are repeated in the same way for the second tube part, f. both second tools, arranged at respective first and second tube part (1, 5), are centered relative to each other and are connected, whereby the tube parts (1, 5) will be centered relative to each other with respect to the interior surfaces (2, 6), and further fixed with a predetermined distance between respective tube part end (4, 8).
A feedthrough adapted for use within a passage, comprising: a body having a first interface region, and a second interface region, wherein the first interface region comprises a platform region; at least one electrical conductor that extends through the body and out of the body to both the first interface region and the second interface region; a printed circuit board attached to the platform region; at least one pin hole defined by the printed circuit board configured to accept the at least one electrical conductor; characterized by: a fastening region of the body comprising: a first travel stop that engages a first shoulder defined by the passage, and prevents travel of the body in a first direction; and a barb configured to flex upon insertion of the body into the passage, and to engage a second shoulder defined by the passage when the body is fully inserted into the passage so to prevent travel of the body in a second direction. a body having a first interface region, and a second interface region, wherein the first interface region comprises a platform region; at least one electrical conductor that extends through the body and out of the body to both the first interface region and the second interface region; a printed circuit board attached to the platform region; at least one pin hole defined by the printed circuit board configured to accept the at least one electrical conductor; characterized by: a fastening region of the body comprising: a first travel stop that engages a first shoulder defined by the passage, and prevents travel of the body in a first direction; and a barb configured to flex upon insertion of the body into the passage, and to engage a second shoulder defined by the passage when the body is fully inserted into the passage so to prevent travel of the body in a second direction. a first travel stop that engages a first shoulder defined by the passage, and prevents travel of the body in a first direction; and a barb configured to flex upon insertion of the body into the passage, and to engage a second shoulder defined by the passage when the body is fully inserted into the passage so to prevent travel of the body in a second direction.
An air-conditioned clothing (1,1a) for use with a helmet which can be used in both circumstances when the helmet is worn and when the helmet is not worn, comprising: a clothing main body which at least covers an upper body of a body; one or more fans which are attached to the clothing main body and which form an air flow path between the clothing main body and the body or an underwear by taking in air from outside and forcefully generate an air flow in the air flow path; an air blow-out unit which is formed between back of a neck of a user and a back collar part of the clothing main body and which blows out the air which flows through the air flow path; a guide sheet which is continuously attached to the back collar part of the clothing main body and which guides the air which blows out from the air blow-out unit to the helmet along back of the neck and back of a head of the user; and an attachment unit which is attached to an edge part of the guide sheet and which is used to attach the guide sheet to the helmet, wherein the air is made to flow through the air flow path by the fans and the flowing air evaporates sweat coming out from the body to cool the body with a heat of evaporation and in a case where the helmet is worn, the air which blows out from the air blow-out unit is guided to the helmet by the guide sheet and taken into the helmet from an air intake which is formed between an inner edge of the helmet and the head of the user in order to circulate the air inside the helmet, characterized in that the attachment unit is an elastic loop belt or a string attached to the edge part of the guide sheet. a clothing main body which at least covers an upper body of a body; one or more fans which are attached to the clothing main body and which form an air flow path between the clothing main body and the body or an underwear by taking in air from outside and forcefully generate an air flow in the air flow path; an air blow-out unit which is formed between back of a neck of a user and a back collar part of the clothing main body and which blows out the air which flows through the air flow path; a guide sheet which is continuously attached to the back collar part of the clothing main body and which guides the air which blows out from the air blow-out unit to the helmet along back of the neck and back of a head of the user; and an attachment unit which is attached to an edge part of the guide sheet and which is used to attach the guide sheet to the helmet, wherein the air is made to flow through the air flow path by the fans and the flowing air evaporates sweat coming out from the body to cool the body with a heat of evaporation and in a case where the helmet is worn, the air which blows out from the air blow-out unit is guided to the helmet by the guide sheet and taken into the helmet from an air intake which is formed between an inner edge of the helmet and the head of the user in order to circulate the air inside the helmet, characterized in that the attachment unit is an elastic loop belt or a string attached to the edge part of the guide sheet.
A computer-implemented method for providing at least one migration risk index, comprising the steps: providing soil data for a location, comprising at least information on the soil composition at that location; providing weather data for said location, comprising at least historical precipitation data for said location; providing a soil mobility model for a product, wherein the soil mobility model is configured to calculate migration data of the product at said location depending on the soil data and the weather data; and determining at least one migration risk index based on the migration data and being representative of a risk that said product migrates down to a lower soil layer at said location. providing soil data for a location, comprising at least information on the soil composition at that location; providing weather data for said location, comprising at least historical precipitation data for said location; providing a soil mobility model for a product, wherein the soil mobility model is configured to calculate migration data of the product at said location depending on the soil data and the weather data; and determining at least one migration risk index based on the migration data and being representative of a risk that said product migrates down to a lower soil layer at said location.
Method for operating a reciprocating piston internal combustion engine in an engine braking mode, in which within one work cycle at least one exhaust valve of at least one cylinder is closed for a first time (1S1, 1S1", 1S1'") and then opened for a first time (1O1, 1O1", 1O1"'), subsequently closed for a second time (2S1, 2S1', 2S1", 2S1"') and then opened for a second time (2O1, 2O1", 2O1'"), in order to discharge by means of a piston of the cylinder gas compressed in the cylinder from the cylinder, characterised in that after the first opening (1O1, 1O1", 1O1'") and before the second closing (2S1, 2S1', 2S1", 2S1'"), the exhaust valve is held open so long that the cylinder is filled with gas flowing via at least one exhaust port out of at least one second cylinder of the reciprocating piston internal combustion engine, and in that after first opening (1O1, 1O1", 1O1'") and before the second closing (2S1, 2S1', 2S1", 2S1'"), the exhaust valve of the first cylinder is held open so long that the first cylinder is filled with respective gas flowing via at least one respective exhaust port out of the second cylinder and at least one third cylinder of the reciprocating piston internal combustion engine, and in that after first opening (1O1, 1O1", 1O1'"), the exhaust valve of the first cylinder is held open to at least 210 degrees crank angle after top dead centre, in particular after ignition top dead centre of the piston of the first cylinder.
A power supply arrangement for a suction unit which is selectively operable using direct current or alternating current, in particular mains current, including a first connection to which a direct current source is connectible or connected, a second connection to which an alternating current source is connectible or connected, at least one third connection to which one or more consuming units (27; 50) of the suction unit are connectible or connected, an electrically isolated converter which is connected on the input side in electrically active manner to the first connection, and a switchover device which is connected in electrically active manner to an output of the converter, is connected to the second connection and is connected to the at least one consuming unit (27; 50), wherein by means of the switchover device it is selectable whether the at least one consuming unit (27; 50) is actively connected to the converter or the second connection for power supply, and wherein the switchover device has one or more components (132, 134) each with an electrical safety clearance, and the safety clearance of such a component (132, 134) is at least 4 mm in respect of the creepage distance and the total of the creepage distances of the components (132, 134) is at least 8 mm.
A method for producing a preparation containing a monoclonal antibody, which comprises a step of removing viruses by filtering viruses in a monoclonal antibody solution using a virus-removing membrane, wherein the monomer content of the monoclonal antibody accounts for 90% or more; the monoclonal antibody concentration in the monoclonal antibody solution ranges from 20 mg/ml to 100 mg/ml; the monoclonal antibody solution contains at least a basic amino acid; and the parvovirus removal rate of the virus-removing membrane satisfies the following conditions: LRV (Log Reduction Value: logarithmic reduction value) ≧ 4. the monomer content of the monoclonal antibody accounts for 90% or more; the monoclonal antibody concentration in the monoclonal antibody solution ranges from 20 mg/ml to 100 mg/ml; the monoclonal antibody solution contains at least a basic amino acid; and the parvovirus removal rate of the virus-removing membrane satisfies the following conditions: LRV (Log Reduction Value: logarithmic reduction value) ≧ 4.
A pneumatic tire comprising: a carcass composed of at least one carcass ply toroidally extending between a pair of bead portions, as a skeleton; a tread rubber arranged on a tire radial-direction outer side of the carcass in a crown portion; a conductive rubber portion arranged in such a manner to penetrate through the tread rubber from a ground-contact region of a tire surface toward a tire radial-direction inner side; and a rubber chafer arranged on a tire width-direction outer surface of each of the bead portions, wherein a conductive member that electrically connects from a tire radial-direction inner end of the conductive rubber portion to the rubber chafer is arranged, the conductive member comprises conductive fibers at least in the vicinity of the tire radial-direction inner end of the conductive rubber portion and the vicinity of the rubber chafer, the conductive member has a volume resistivity of 1 × 10 8 Ω·cm or lower, at least one belt layer is arranged between the carcass and the tread rubber, the pneumatic tire is characterized in that a belt-end cushion rubber is arranged between the belt layer and the carcass at a tire widthwise end of the belt layer, and the conductive member comprises the conductive fibers and the belt-end cushion rubber. a carcass composed of at least one carcass ply toroidally extending between a pair of bead portions, as a skeleton; a tread rubber arranged on a tire radial-direction outer side of the carcass in a crown portion; a conductive rubber portion arranged in such a manner to penetrate through the tread rubber from a ground-contact region of a tire surface toward a tire radial-direction inner side; and a rubber chafer arranged on a tire width-direction outer surface of each of the bead portions, wherein a conductive member that electrically connects from a tire radial-direction inner end of the conductive rubber portion to the rubber chafer is arranged, the conductive member comprises conductive fibers at least in the vicinity of the tire radial-direction inner end of the conductive rubber portion and the vicinity of the rubber chafer, the conductive member has a volume resistivity of 1 × 10 8 Ω·cm or lower, at least one belt layer is arranged between the carcass and the tread rubber, the pneumatic tire is characterized in that a belt-end cushion rubber is arranged between the belt layer and the carcass at a tire widthwise end of the belt layer, and the conductive member comprises the conductive fibers and the belt-end cushion rubber.
A pipette tip comprising a proximal region, a distal region, the proximal region comprising a plurality of axially oriented ribs (80, 85), wherein: the proximal region comprises an exterior surface and an annular flange at the proximal terminus of the proximal region; the ribs (80, 85) each extend from the annular flange to a junction between the proximal region and the distal region corresponding to a rib terminus (82, 90); the distal region wall thickness tapers continuously from (a) a point at the rib terminus (82, 90) or a point between the rib terminus (82, 90) and one-quarter of the axial distance from the terminus of the distal region to the rib terminus (82, 90), to (b) the distal region terminus, and the wall thickness at the distal region terminus is 0.01016 cm (0.0040 inches) to 0.01397 cm (0.0055 inches). the proximal region comprises an exterior surface and an annular flange at the proximal terminus of the proximal region; the ribs (80, 85) each extend from the annular flange to a junction between the proximal region and the distal region corresponding to a rib terminus (82, 90); the distal region wall thickness tapers continuously from (a) a point at the rib terminus (82, 90) or a point between the rib terminus (82, 90) and one-quarter of the axial distance from the terminus of the distal region to the rib terminus (82, 90), to (b) the distal region terminus, and (a) a point at the rib terminus (82, 90) or a point between the rib terminus (82, 90) and one-quarter of the axial distance from the terminus of the distal region to the rib terminus (82, 90), to (b) the distal region terminus, and the wall thickness at the distal region terminus is 0.01016 cm (0.0040 inches) to 0.01397 cm (0.0055 inches).
An antitumor agent for use in the treatment of a malignant tumor in a patient expressing EGFR having exon 20 insertion mutation, the antitumor agent comprising a compound selected from the group consisting of: -N-(4-amino-6-methyl-5-(quinolin-3-yl)-8,9-dihydropyrimido[5,4-b]indolizin-8-yl)acrylamide; -N-(4-amino-6-methylene-5-(quinolin-3-yl)-7,8-dihydro-6H-pyrimido[5,4-b]pyrrolizin-7-yl)acrylamide; (S,E)-N-(4-amino-6-methylene-5-(quinolin-3-yl)-7,8-dihydro-6H-pyrimido[5,4-b]pyrrolizin-7-yl)-3-chloroacrylamide; and -N-(4-amino-6-methyl-5-(quinolin-3-yl)-8,9-dihydropyrimido[5,4-b]indolizin-8-yl)-N-methylacrylamide, or a salt thereof. -N-(4-amino-6-methyl-5-(quinolin-3-yl)-8,9-dihydropyrimido[5,4-b]indolizin-8-yl)acrylamide; -N-(4-amino-6-methylene-5-(quinolin-3-yl)-7,8-dihydro-6H-pyrimido[5,4-b]pyrrolizin-7-yl)acrylamide; (S,E)-N-(4-amino-6-methylene-5-(quinolin-3-yl)-7,8-dihydro-6H-pyrimido[5,4-b]pyrrolizin-7-yl)-3-chloroacrylamide; and -N-(4-amino-6-methyl-5-(quinolin-3-yl)-8,9-dihydropyrimido[5,4-b]indolizin-8-yl)-N-methylacrylamide, or a salt thereof.
Machine for the decoration of three-dimensional articles, comprising: a base, support means for a plurality of articles to be decorated, associated with said base, a decoration group of the articles associated with said base, said decoration group comprising a plurality of print heads, said support means comprising at least one carousel rotatable about a first rotation axis, and provided with a plurality of support areas for respective articles to be decorated, said carousel being associated with first rotatable actuation means for selectively positioning each support area at a respective print head, each of said print heads comprising means for varying the tilt of the respective head for the correct positioning of the ejector nozzles with respect to the surface to be decorated of the respective article, wherein said means for varying the tilt comprise a rotary actuator and a mechanism suitable to transform the motion of the output shaft of the rotary actuator into a rotation motion of said head around a respective pivoting axis, wherein said decoration group comprises a support slab of said print heads, and translation means of each of said print heads along a respective translation direction perpendicular to said first rotation axis, characterized in that said mechanism comprises a crank mechanism which comprises a first member pivoted to said output shaft, and a second member pivoted to both said first member and to said head, and in that said head is associated with a respective support pivoted to said slab about said pivoting axis perpendicular to said first rotation axis a base, support means for a plurality of articles to be decorated, associated with said base, a decoration group of the articles associated with said base, said decoration group comprising a plurality of print heads, said support means comprising at least one carousel rotatable about a first rotation axis, and provided with a plurality of support areas for respective articles to be decorated, said carousel being associated with first rotatable actuation means for selectively positioning each support area at a respective print head, each of said print heads comprising means for varying the tilt of the respective head for the correct positioning of the ejector nozzles with respect to the surface to be decorated of the respective article, wherein said means for varying the tilt comprise a rotary actuator and a mechanism suitable to transform the motion of the output shaft of the rotary actuator into a rotation motion of said head around a respective pivoting axis, wherein said decoration group comprises a support slab of said print heads, and translation means of each of said print heads along a respective translation direction perpendicular to said first rotation axis, characterized in that said mechanism comprises a crank mechanism which comprises a first member pivoted to said output shaft, and a second member pivoted to both said first member and to said head, and in that said head is associated with a respective support pivoted to said slab about said pivoting axis perpendicular to said first rotation axis