mhurhangee/ep-ind-claims huggingface dataset:
A method for testing a therapeutic effect of cancer therapy with at least one anticancer drug selected from anticancer drugs comprising as an effective ingredient an anti-CD4 antibody, anticancer drugs comprising as an effective ingredient an antagonist for an inhibitory immune checkpoint molecule, and anticancer drugs comprising as an effective ingredient an agonist for a co-stimulatory immune checkpoint molecule, said method comprising investigating expression of at least one immune checkpoint receptor selected from the group consisting of PD-1, CD137, and TIM-3; CD8; and at least one cell surface molecule selected from the group consisting of CD44 and CD45RO; on T cells using a blood sample derived from a patient who received said at least one anticancer drug, wherein induction of a T cell population which is positive for said immune checkpoint molecule mentioned in above and positive for CD8, and which shows high expression of CD44 and/or high expression of CD45RO, indicates that said anticancer drug is producing a therapeutic effect in said patient. at least one immune checkpoint receptor selected from the group consisting of PD-1, CD137, and TIM-3; CD8; and at least one cell surface molecule selected from the group consisting of CD44 and CD45RO;
A method of forming an organic polymeric particle, comprising: forming a core of an organic hydrophilic polymer with monomers that contain an acid group, a latent acid group, or a combination thereof; forming a shell that comprises an organic polymer with monomers that contain an acid group, a latent acid group, or a combination thereof to encapsulate the core, the organic polymer including monomers selected from the group consisting of styrene, methyl methacrylate and acrylonitrile, and 1 to 25 weight parts of monomers that contain a latent acid group; wherein the latent acid groups of the organic polymer include methyl acrylate or butyl acrylate, where the shell has an initial size; expanding the core to form a hollow porous structure from the shell, where the hollow porous structure has an expanded size larger than an initial size of the shell, and hydrolysing the acid group, latent acid group, or combination thereof of the hollow porous structure and of the organic hydrophilic polymer, to give the organic polymeric particle a void volume fraction of 40 percent to 85 percent. forming a core of an organic hydrophilic polymer with monomers that contain an acid group, a latent acid group, or a combination thereof; forming a shell that comprises an organic polymer with monomers that contain an acid group, a latent acid group, or a combination thereof to encapsulate the core, the organic polymer including monomers selected from the group consisting of styrene, methyl methacrylate and acrylonitrile, and 1 to 25 weight parts of monomers that contain a latent acid group; wherein the latent acid groups of the organic polymer include methyl acrylate or butyl acrylate, where the shell has an initial size; expanding the core to form a hollow porous structure from the shell, where the hollow porous structure has an expanded size larger than an initial size of the shell, and hydrolysing the acid group, latent acid group, or combination thereof of the hollow porous structure and of the organic hydrophilic polymer, to give the organic polymeric particle a void volume fraction of 40 percent to 85 percent.
A method comprising: extruding a thermally expandable material to have a particular cross-sectional profile; inserting the expandable material into a molding tool; shaping the expandable material within the molding tool; and overmolding a carrier material onto a portion of the expandable material within the molding tool, the overmolding step includes injecting the carrier material into the molding tool at a temperature above a melting temperature of the expandable material. extruding a thermally expandable material to have a particular cross-sectional profile; inserting the expandable material into a molding tool; shaping the expandable material within the molding tool; and overmolding a carrier material onto a portion of the expandable material within the molding tool, the overmolding step includes injecting the carrier material into the molding tool at a temperature above a melting temperature of the expandable material.
A door holder, comprising a retainer housing, which is connectable to either a door or a door frame, and a door retaining rod (20; 120), which penetrates an opening of the retainer housing and can be articulated with the other of door and door frame, wherein the door retaining rod (20, 120) has at least one braking surface (24a, 24b; 124a, 124b), wherein at least one braking element displaceable in the direction of the at least one braking surface (24a, 24b; 124a, 124b) is arranged on the retainer housing, which braking element can be brought into contact at least in sections (41, 42, 43) with the at least one braking surface (24a, 24b; 124a, 124b) of the door retaining rod (20; 120) and thus generates a primary brake force component against the displacement of the door retaining rod (20; 120), wherein the door retaining rod (20; 120) has at least one guide surface (25a, 25b; 125a, 125b) inclined in relation to the braking surface (24a, 24b; 124a, 124b), wherein at least one guide element (235a, 235b) is arranged on the retainer housing, which guide element can be brought at least in regions into contact with the at least one guide surface (25a, 25b; 125a, 125b) and generates a secondary brake force component against the displacement of the door retaining rod (20; 120), characterized in that the guide element is formed as a pin (235a, 235b), that the pin (235a, 235b; 235a', 235b') is accommodated in a guide part of the retainer housing, and that an end face of the pin (235a, 235b; 235a', 235b') protrudes axially into the opening or at least delimits the opening. a retainer housing, which is connectable to either a door or a door frame, and a door retaining rod (20; 120), which penetrates an opening of the retainer housing and can be articulated with the other of door and door frame,
A computer-implemented method comprising: sending, from a first system to a first data source, encryption key data; sending, from the first system to a second data source, the encryption key data; receiving, at a second system from the first data source, first encrypted input data, the first encrypted input data being encrypted based at least in part on the encryption key data; receiving, at the second system from the second data source, second encrypted input data, the second encrypted input data being encrypted based at least in part on the encryption key data; generating, by the second system, encrypted summation data corresponding to a sum of the first encrypted input data and the second encrypted input data, wherein the second system is not in possession of the encryption key data, and wherein the first encrypted input data and the second encrypted input data are additively homomorphic; sending, from the second system to the first system using a secure connection, the encrypted summation data, wherein the first system is trusted to learn the sum of data from each of the first and second data sources; and generating, by the first system, summation data by decrypting, based at least in part on the encryption key data, the encrypted summation data. sending, from a first system to a first data source, encryption key data; sending, from the first system to a second data source, the encryption key data; receiving, at a second system from the first data source, first encrypted input data, the first encrypted input data being encrypted based at least in part on the encryption key data; receiving, at the second system from the second data source, second encrypted input data, the second encrypted input data being encrypted based at least in part on the encryption key data; generating, by the second system, encrypted summation data corresponding to a sum of the first encrypted input data and the second encrypted input data, wherein the second system is not in possession of the encryption key data, and wherein the first encrypted input data and the second encrypted input data are additively homomorphic; sending, from the second system to the first system using a secure connection, the encrypted summation data, wherein the first system is trusted to learn the sum of data from each of the first and second data sources; and generating, by the first system, summation data by decrypting, based at least in part on the encryption key data, the encrypted summation data.
Metallic foam body, comprising (a) a metallic foam body substrate made of at least one metal or metal alloy A; and (b) a layer of a metal or metal alloy B present on at least a part of the surface of the metallic foam body substrate (a), wherein A and B differ in the grain size of the metal or metal alloy; obtainable by a process comprising the steps: (i) provision of a porous organic polymer foam; (ii) deposition of at least one metal or metal alloy A on the porous organic polymer foam; (iii) burning off of the porous organic polymer foam to obtain the metallic foam body substrate (a); and (iv) deposition by electroplating of the metallic layer (b) of a metal or metal alloy B at least on a part of the surface of the metallic foam body (a); wherein step (ii) comprises the steps: deposition of a first metallic layer containing a metal or metal alloy A1 by a chemical or physical vapor deposition method; and deposition of a second metallic layer containing a metal or metal alloy A2 by electroplating; wherein A1 and A2 are identical or different, and wherein A1 is selected from a group consisting of Ni, Cr, Co, Cu, Ag, and any alloy thereof; and wherein A2 and B are silver. (a) a metallic foam body substrate made of at least one metal or metal alloy A; and (b) a layer of a metal or metal alloy B present on at least a part of the surface of the metallic foam body substrate (a), wherein A and B differ in the grain size of the metal or metal alloy; (i) provision of a porous organic polymer foam; (ii) deposition of at least one metal or metal alloy A on the porous organic polymer foam; (iii) burning off of the porous organic polymer foam to obtain the metallic foam body substrate (a); and (iv) deposition by electroplating of the metallic layer (b) of a metal or metal alloy B at least on a part of the surface of the metallic foam body (a); deposition of a first metallic layer containing a metal or metal alloy A1 by a chemical or physical vapor deposition method; and deposition of a second metallic layer containing a metal or metal alloy A2 by electroplating;
An assembly, comprising a first water jacket portion establishing a plurality of first fluid channels that are situated to facilitate fluid movement along at least a first plane; a second water jacket portion situated near the first water jacket portion, the second water jacket portion establishing a plurality of second fluid channels that are situated to facilitate fluid movement along at least a second plane that is generally parallel to the first plane; and at least one connector portion establishing a plurality of connector fluid channels that are situated to facilitate fluid movement between at least one of the first fluid channels and at least one of the second fluid channels along a direction that is transverse to the first and second plane; an inlet to the first water jacket portion on a first side of the first water jacket portion; and an outlet from the second water jacket portion on the first side of the first water jacket portion; wherein the first fluid channels are configured to carry at least some of the fluid in a direction from the first side of the first water jacket portion toward a second, opposite side of the first water jacket portion; the connector fluid channels are configured to carry the at least some of the fluid from the first fluid channels to the second fluid channels; the second fluid channels are configured to carry the at least some of the fluid received from the connector fluid channels in another direction from the second side toward the first side and toward the outlet; an engine cylinder block, wherein the first water jacket portion includes a cylinder block outlet for directing some fluid from the first fluid channels toward the engine cylinder block; a vehicle cabin heater, wherein the outlet from the second water jacket portion directs the at least some of the fluid toward the vehicle cabin heater; and a flow control element that is selectively controllable to prioritize fluid flow through the cylinder block outlet when warming engine oil is desired; and prioritize fluid flow through the outlet from the second water jacket portion when warming the vehicle cabin heater is desired.
A hearing instrument (48, 50) including a housing configured to be worn at an ear of a person, the housing comprising a top part and respective left and right sides, the hearing instrument (48, 50) including an antenna unit, the antenna unit comprising: an electrically conductive material having a first surface with a slot, where the electrically conductive material is arranged at the top part of the housing, a feed connection provided to supply the antenna unit with an electrical signal, the feed and slot arranged so that when the slot is fed by a signal, an electric field is created across the slot, whereby the emitted electric field has the main part of the electric field component in the direction across the slot, the antenna unit further comprises a first loading wing electrically connected to the first surface along the length of the first loading wing and arranged at an angle relative to the electrically conductive material at a right or left side of the housing, so that during transmission the first loading wing focus the nearfield part of the emitted field inside the hearing instrument, the first loading wing being electrically connected to the first surface continuously along substantially the entire length of the first loading wing. an electrically conductive material having a first surface with a slot, where the electrically conductive material is arranged at the top part of the housing, a feed connection provided to supply the antenna unit with an electrical signal, the feed and slot arranged so that when the slot is fed by a signal, an electric field is created across the slot, whereby the emitted electric field has the main part of the electric field component in the direction across the slot, the antenna unit further comprises a first loading wing electrically connected to the first surface along the length of the first loading wing and arranged at an angle relative to the electrically conductive material at a right or left side of the housing, so that during transmission the first loading wing focus the nearfield part of the emitted field inside the hearing instrument, the first loading wing being electrically connected to the first surface continuously along substantially the entire length of the first loading wing.
Strap intended for a sling for persons, where the strap is elongated with short end edges and longer lateral edges and comprises a first belt and a second belt, where each belt (9,11)comprises an inside and an outside, where the insides are turned towards one another, and the outsides are turned away from one another, where the first belt and the second belt comprise warps and wefts, where the strap has a longitudinal direction that is parallel to the warps, and a transverse direction that is parallel to the wefts, where in the longitudinal direction of the strap there are a number of first sections where the first belt and the second belt are interwoven, and second sections are provided between them, where the first belt and the second belt are not interwoven, so that an eye is formed in each of the second sections, where in the longitudinal direction of the strap there is a sequence of colours and/or patterns, marking each eye in the strap unambiguously, characterized in that warps are produced in at least three different colours, and in that the warps are led in two outer layers and at least one intermediate layer in each of the two belts (9,11) with optional colours in the individual layers.
A cyclone for separating sticky particles from gas streams, in which the flow cross-section at the end of the inlet duct has a triangular expansion Q in direction of the particle outlet, which laterally is formed by the cylindrical outer wall and by an outer boundary, characterized in that the outer angle of inclination β between the outer boundary and the vertical, proceeding from the end of the inlet duct, extends from 30° to 0° in flow direction of the gas streams.
Operating apparatus for a medical device, with a projection facility, which is configured for real and/or virtual projection of an operator surface (7, 11, 12) onto a display element (5, 8, 9), and with a capture facility for non-contact capturing of an interaction (28, 29, 31) of an operator with the projected operator surface (7, 11, 12), wherein a sensor system for independent capturing of the interaction (28, 29, 31) separate from the capture facility is arranged on the display element (5, 8, 9), characterised in that - the display element (5, 8, 9) has a machine-readable code (13, 14, 15), which encodes a layout and/or a function selection of the operator surface (7, 11, 12), wherein - the operating apparatus is configured to read the code (13, 14, 15) and to adapt the projected operator surface (7, 11, 12) as a function of the encoded layout and/or the encoded function selection. - the display element (5, 8, 9) has a machine-readable code (13, 14, 15), which encodes a layout and/or a function selection of the operator surface (7, 11, 12), wherein - the operating apparatus is configured to read the code (13, 14, 15) and to adapt the projected operator surface (7, 11, 12) as a function of the encoded layout and/or the encoded function selection.
Medium support member, for a printing system, having a first surface of supporting a print medium and a second surface opposite to said first surface, comprising a plurality of recesses formed in said first surface and a plurality of protrusions formed in said second surface such that each recess has an associated protrusion opposite to said recess; characterised by each recess having an air passage connecting the recess with the interprotrusional space, wherein the protrusions are formed such that the medium support member is supporter by the plurality of protrusions when the medium support member is placed on a substantially flat support surface.
An optical device for generating a beat frequency between two optical wavelengths, the device comprising two waveguides (2a, 2b) and a grating layer that is common to both waveguides, characterised in that the two waveguides (2a, 2b) have different widths.
Device for controlling the flow of a fluid with in-built pressure threshold detection comprising flow interrupting and enabling means intended to be arranged in a pipe of a frame connecting a fluid source and an area to supply with fluid, said frame comprising at least one electrically conducting area, the flow interrupting and enabling means comprising a body bearing a first obturator seat, an obturator configured to cooperate in a leak tight manner with the first obturator seat, a first elastic return means applying a return force on the obturator in the direction of the first obturator seat, said body comprising an internal element bearing the first obturator seat, characterized in that said internal element is electrically conducting, said body also comprising an electrically insulating external element so as to be electrically insulated from at least the conducting area, the device also comprising an electrical connection intended to be connected to a detection system, said detection system forming, with at least the conducting area of the frame and the internal element, an electrical detection circuit, the internal element being in permanent contact with the electrical connection, the internal element being capable of sliding in a substantially leak tight manner in the external element such that, when the pressure of the fluid exceeds the threshold pressure, the electric circuit passes from a closed state to an open state or when the pressure of the fluid exceeds the threshold pressure the electric circuit passes from an open state to a closed state.
A digital radio receiver adapted to receive radio signals having a carrier frequency and modulated using continuous phase frequency shift keying, the receiver comprising means for receiving said radio signal, and a matched filter bank comprising a plurality of filters (20, 22) each of which corresponding to a different bit pattern for determining a bit sequence from said signal, wherein the receiver is arranged to obtain information from one of said filters relating to a phase of said signal when said filter is matched to a bit pattern on a first occasion; obtain information from said filter relating to a phase of said signal when said filter is matched to the bit pattern on a second occasion; characterised in that the digital radio receiver is further arranged to: estimate a frequency drift of said carrier frequency using a difference in phase between the phase determined on the first occasion and the phase determined on the second occasion if said bit sequence between said first and second occasions comprises an equal number of high and low bits, wherein said frequency drift is a change in a frequency offset between said carrier frequency and a nominal carrier frequency over time. estimate a frequency drift of said carrier frequency using a difference in phase between the phase determined on the first occasion and the phase determined on the second occasion if said bit sequence between said first and second occasions comprises an equal number of high and low bits, wherein said frequency drift is a change in a frequency offset between said carrier frequency and a nominal carrier frequency over time.