mhurhangee/ep-ind-claims huggingface dataset:
A method for producing platelets from megakaryocytes comprising the steps of: a) providing a non-adherent, feeder-free culture of megakaryocytes; b) contacting the megakaryocytes with TPO or a TPO agonist to cause the formation in culture of pro-platelets, wherein the pro-platelets release platelets, at least 60% of which are positive for CD41a and CD42b expression; or contacting the megakaryocytes with hematopoietic expansion medium and TPO or a TPO agonist, SCF, IL-6 and IL-9 or TPO or a TPO agonist, SCF, and IL-11 to cause the formation in culture of pro-platelets, wherein the pro-platelets release platelets, at least 60% of which are positive for CD41a and CD42b expression, wherein said TPO agonist comprises one or more of: ADP, epinephrine, thrombin, collagen, romiplostim, eltrombopag (SB497115, Promacta), recombinant human thrombopoietin, pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF), Fab 59, AMG 531, Peg-TPOmp, AKR-501, monoclonal TPO agonist antibodies, polyclonal TPO agonist antibodies, TPO minibodies, VB22B sc(Fv)2, domain subclass-converted TPO agonist antibodies, MA01G4G344, recombinant human thrombopoietins, or recombinant TPO fusion proteins; and c) isolating the platelets, optionally wherein substantially all the isolated platelets are functional. a) providing a non-adherent, feeder-free culture of megakaryocytes; b) contacting the megakaryocytes with TPO or a TPO agonist to cause the formation in culture of pro-platelets, wherein the pro-platelets release platelets, at least 60% of which are positive for CD41a and CD42b expression; or contacting the megakaryocytes with hematopoietic expansion medium and TPO or a TPO agonist, SCF, IL-6 and IL-9 or TPO or a TPO agonist, SCF, and IL-11 to cause the formation in culture of pro-platelets, wherein the pro-platelets release platelets, at least 60% of which are positive for CD41a and CD42b expression, wherein said TPO agonist comprises one or more of: ADP, epinephrine, thrombin, collagen, romiplostim, eltrombopag (SB497115, Promacta), recombinant human thrombopoietin, pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF), Fab 59, AMG 531, Peg-TPOmp, AKR-501, monoclonal TPO agonist antibodies, polyclonal TPO agonist antibodies, TPO minibodies, VB22B sc(Fv)2, domain subclass-converted TPO agonist antibodies, MA01G4G344, recombinant human thrombopoietins, or recombinant TPO fusion proteins; and c) isolating the platelets, optionally wherein substantially all the isolated platelets are functional.
A notification system of an elevator, comprising: a first receiver provided in an elevator hall; a control unit which assigns a car selected from among a plurality of elevator cars to a service floor acquired from an identification medium by the first receiver by means of wireless communication; a plurality of second receivers provided respectively in the plurality of elevator cars; and a notification control device configured such that when a car arrives at a hall, in the case where the car concerned is not assigned to the service floor acquired from the identification medium by the second receiver in the car concerned by means of wireless communication, a speaker provided in the car concerned is caused to notify, with voice, the user about the service floor concerned and the car assigned to the service floor concerned. a first receiver provided in an elevator hall; a control unit which assigns a car selected from among a plurality of elevator cars to a service floor acquired from an identification medium by the first receiver by means of wireless communication; a plurality of second receivers provided respectively in the plurality of elevator cars; and a notification control device configured such that when a car arrives at a hall, in the case where the car concerned is not assigned to the service floor acquired from the identification medium by the second receiver in the car concerned by means of wireless communication, a speaker provided in the car concerned is caused to notify, with voice, the user about the service floor concerned and the car assigned to the service floor concerned.
Granular washing, cleaning or treatment agent additive comprising - 5 to 90 wt % of particulate carrier material having an oil absorption capacity of at least 100 mL/ 100 g, wherein the carrier material comprises less than 20 wt % of particulate water-soluble components, - 10 to 80 wt % of capsules that have a mean diameter d 50 of 1 to 100 μm and in which one or more benefit agents is/are enclosed, and - comprises at least 40 wt % water. - 5 to 90 wt % of particulate carrier material having an oil absorption capacity of at least 100 mL/ 100 g, wherein the carrier material comprises less than 20 wt % of particulate water-soluble components, - 10 to 80 wt % of capsules that have a mean diameter d 50 of 1 to 100 μm and in which one or more benefit agents is/are enclosed, and - comprises at least 40 wt % water.
A method of making a spray gun reservoir component (54; 260) including a liquid outlet (64; 272) surrounding a longitudinal axis, an outer face extending away from the liquid outlet (64; 272), a centerline plane including the longitudinal axis, and an attachment plane defined orthogonally to the longitudinal axis and the centerline plane, the outer face comprising a retention feature (140a, 140b; 340a, 340b) extending away from the centerline plane and generally parallel to the attachment plane, the method comprising: providing plastic injection molding tooling including first and second tooling components collectively defining a cavity having a shape of the spray gun reservoir component (54; 260); injecting molten plastic into the cavity to form the spray gun reservoir component (54; 260); and sliding the first and second tooling components relative to one another to separate the first and second tooling components and release the spray gun reservoir component (54; 260); wherein the step of sliding includes manipulating the first and second tooling components along a slide tool path that is aligned with the retention feature (140a, 140b; 340a, 340b). providing plastic injection molding tooling including first and second tooling components collectively defining a cavity having a shape of the spray gun reservoir component (54; 260); injecting molten plastic into the cavity to form the spray gun reservoir component (54; 260); and sliding the first and second tooling components relative to one another to separate the first and second tooling components and release the spray gun reservoir component (54; 260); wherein the step of sliding includes manipulating the first and second tooling components along a slide tool path that is aligned with the retention feature (140a, 140b; 340a, 340b).
Bearing bush comprising at least one sealing element and a bearing element, wherein the sealing element is provided with at least one sealing lip, wherein the bearing element is of substantially tubular configuration, wherein the sealing element is connected to the bearing element in a form-fitting manner, characterized in that the bearing element has, on its outer circumference, a plurality of elevations which run in an axial direction, wherein the inner diameter of the bearing element is greater in the portions assigned to the elevations than in the remaining portions.
A device for joining material by anchoring an insert comprising a first material in a structure comprising a second material, wherein the first material is solid and comprises thermoplastic properties and wherein the second material is solid and is penetrable by the first material when in a liquefied state, said device comprising: a vibration device being configured to transmit vibrations to said insert to cause at least partial liquefaction thereof and being arranged to move, relative to said structure, along an insertion direction to insert said insert at least partly into said structure, a contact sensor being connected to the vibration device and being adapted to move together with the vibration device along the insertion direction, the contact sensor having a sensor body being adapted to detect contact with said structure, and a controller connected to the contact sensor and adapted for receiving a contact signal from the contact sensor indicating that the sensor body has come into contact with said structure, the controller comprising control means for interrupting, based on receipt of said signal, at least one of: i) a movement of the vibration device along the insertion direction, and ii) a transmission of vibrations from the vibration device to said insert. a vibration device being configured to transmit vibrations to said insert to cause at least partial liquefaction thereof and being arranged to move, relative to said structure, along an insertion direction to insert said insert at least partly into said structure, a contact sensor being connected to the vibration device and being adapted to move together with the vibration device along the insertion direction, the contact sensor having a sensor body being adapted to detect contact with said structure, and a controller connected to the contact sensor and adapted for receiving a contact signal from the contact sensor indicating that the sensor body has come into contact with said structure, the controller comprising control means for interrupting, based on receipt of said signal, at least one of: i) a movement of the vibration device along the insertion direction, and ii) a transmission of vibrations from the vibration device to said insert.
Apparatus 301, 301', 301" for spaced application of patches 205 of a first material onto a web of a second material, the apparatus comprising: means for introducing a web of the first material including clamping mean 311 for clamping the web of the first material, the clamping means 311 arranged to drive the web of the first material at a constant speed as the web of the first material is introduced; a cam for repeatedly accelerating the web of the first material downstream of the clamping means 311; a glue applicator 315 for applying glue to the web of the first materials; a cutter 317 comprising at least one cutter blade for cutting the glued web of the first material to form glued patches of the first material; means for introducing the web of the second material; and a transfer drum 323 for applying the glued patches of the first material to the web of the second material. means for introducing a web of the first material including clamping mean 311 for clamping the web of the first material, the clamping means 311 arranged to drive the web of the first material at a constant speed as the web of the first material is introduced; a cam for repeatedly accelerating the web of the first material downstream of the clamping means 311; a glue applicator 315 for applying glue to the web of the first materials; a cutter 317 comprising at least one cutter blade for cutting the glued web of the first material to form glued patches of the first material; means for introducing the web of the second material; and a transfer drum 323 for applying the glued patches of the first material to the web of the second material.
A turbomachine component defined at least partially in a radial direction and an axial direction orthogonal to the radial direction, comprising: a body defining an outer surface configured to be, in use, in thermal communication with a gas path flow in the axial direction; a thermal regulation channel system defined within the body, comprising: two radial channels; and at least one pair of axial channels that are radially and/or axially aligned on opposite circumferential sides of the two radial channels and which connect the two radial channels; and at least one film hole defined through a wall of the body and positioned to be in fluid communication with a radial channel, so that flow from the thermal regulation channel system can effuse into the gas path flow. a body defining an outer surface configured to be, in use, in thermal communication with a gas path flow in the axial direction; a thermal regulation channel system defined within the body, comprising: two radial channels; and at least one pair of axial channels that are radially and/or axially aligned on opposite circumferential sides of the two radial channels and which connect the two radial channels; and two radial channels; and at least one pair of axial channels that are radially and/or axially aligned on opposite circumferential sides of the two radial channels and which connect the two radial channels; and at least one film hole defined through a wall of the body and positioned to be in fluid communication with a radial channel, so that flow from the thermal regulation channel system can effuse into the gas path flow.
A method for automatically inspecting an ophthalmic lens comprising the steps of: continuously moving the lens along a predetermined path smoothly into and through a lens inspection position; synchronizing the movement of the lens with the actuation of an illumination system such that the illumination system is actuated to directs a light beam through the lens, when the lens is in the inspection position, towards an array of pixels, wherein said lens comprises a centre optical zone, an outer zone and an annulus; synchronizing the movement of the lens with the actuation of an imaging subsystem such that the imaging subsystem is actuated to open a camera shutter when the lens is in the lens inspection position, wherein the imaging subsystem includes the array of pixels, wherein the light beam is sufficient to allow the capture of an image on the array of pixels; selectively blocking light transmitted by regular features of the centre optical zone and the outer zone of the lens at a stop and transmitting light transmitted by the annulus and irregular features of the centre optical zone and the outer zone of the lens onto the pixel array; assigning to each pixel a data value representing the intensity of the light beam on the pixel; and processing said data values according to a predetermined program to determine if the lens contains any one of a plurality of predetermined conditions. continuously moving the lens along a predetermined path smoothly into and through a lens inspection position; synchronizing the movement of the lens with the actuation of an illumination system such that the illumination system is actuated to directs a light beam through the lens, when the lens is in the inspection position, towards an array of pixels, wherein said lens comprises a centre optical zone, an outer zone and an annulus; synchronizing the movement of the lens with the actuation of an imaging subsystem such that the imaging subsystem is actuated to open a camera shutter when the lens is in the lens inspection position, wherein the imaging subsystem includes the array of pixels, wherein the light beam is sufficient to allow the capture of an image on the array of pixels; selectively blocking light transmitted by regular features of the centre optical zone and the outer zone of the lens at a stop and transmitting light transmitted by the annulus and irregular features of the centre optical zone and the outer zone of the lens onto the pixel array; assigning to each pixel a data value representing the intensity of the light beam on the pixel; and processing said data values according to a predetermined program to determine if the lens contains any one of a plurality of predetermined conditions.
Steam extractor device with a steam extractor hood, wherein the steam extractor device has at least one filter element and the filter element has filter material, characterised in that the filter material is present in the filter element in layers (121, 122, 123), wherein the composition of the filter material in one layer differs from that in at least one further layer of the filter element, the filter material represents a mixture of a mineral adsorber and a further mineral adsorber or at least one mineral adsorber and active carbon and the filter material consists predominantly of one or more mineral adsorbers in at least one layer of the filter element.
A drive axle assembly (32, 34) comprising: a differential assembly including a side gear; a wheel hub assembly including a hub and a cap (56, 220); an axle shaft that is rotatable about an axis and extends axially from the differential assembly toward the cap such that the axle shaft is received in the hub, characterised in that the axle shaft being moveable along the axis relative to the side gear and the cap (56, 220); and an actuator mechanism that is configured to actuate the axle shaft along the axis between a first axial position in which the differential assembly provides torque to the wheel hub assembly and a second axial position in which the wheel hub assembly is disconnected from the differential assembly such that the differential assembly does not provide torque to the wheel hub assembly. a differential assembly including a side gear; a wheel hub assembly including a hub and a cap (56, 220); an axle shaft that is rotatable about an axis and extends axially from the differential assembly toward the cap such that the axle shaft is received in the hub, characterised in that the axle shaft being moveable along the axis relative to the side gear and the cap (56, 220); and an actuator mechanism that is configured to actuate the axle shaft along the axis between a first axial position in which the differential assembly provides torque to the wheel hub assembly and a second axial position in which the wheel hub assembly is disconnected from the differential assembly such that the differential assembly does not provide torque to the wheel hub assembly.
Composition for production of rigid polyurethane foam, comprising at least one isocyanate component, a polyol component, optionally a catalyst which catalyses the formation of a urethane or isocyanurate bond, optionally blowing agent, wherein the composition additionally includes at least one OH-functional compound obtainable by the partial or complete hydrogenation of ketone-aldehyde resins, wherein this OH-functional compound contains at least one structural element of the formula and optionally of the formulae and/or, with R = aromatic hydrocarbyl radical having 6-14 carbon atoms or (cyclo)aliphatic hydrocarbyl radical having 1-12 carbon atoms, where the hydrocarbyl radicals may optionally be substituted, R 1 = H, CH 2 OH, R 2 = H, or a radical of the formula -(CH 2 -CH(R')O-) y -H where R' is hydrogen, methyl, ethyl or phenyl and y = 1 to 50, k = 2 to 15, preferably 3 to 12, more preferably 4 to 11, m = 0 to 13, preferably 0 to 9, 1 = 0 to 2, where the sum of k + l + m is from 5 to 15, preferably from 5 to 12, and k > m, with the proviso that at least 90 parts by weight of the polyols present have an OH number greater than 100, preferably greater than 150, especially greater than 200, based on 100 parts by weight of polyol component. R = aromatic hydrocarbyl radical having 6-14 carbon atoms or (cyclo)aliphatic hydrocarbyl radical having 1-12 carbon atoms, where the hydrocarbyl radicals may optionally be substituted, R 1 = H, CH 2 OH, R 2 = H, or a radical of the formula -(CH 2 -CH(R')O-) y -H where R' is hydrogen, methyl, ethyl or phenyl and y = 1 to 50, k = 2 to 15, preferably 3 to 12, more preferably 4 to 11, m = 0 to 13, preferably 0 to 9, 1 = 0 to 2,
A metal disc configured as a cymbal having a damping ring that has, in a middle region thereof, a hole for releasable arrangement on a frame provided with fastening means, wherein the damping ring, which is formed of a vibration-damping material, is arranged below the aforementioned hole, and abuts at least against a part of the total area of the aforementioned metal disc that is concentric to the hole and is formed of an elastic material, the metal disc being characterized in that the damping ring has a minimum diameter of 40 mm.
A method for producing an aqueous extract of a cereal, said method comprising the steps of: a. providing grains of a cereal; b. subjecting the cereal grains to a step of germination thereby obtaining germinated grains, wherein said step of germination comprises incubating said grains in an aqueous solution until the grains have a water content of at least 30%, wherein at least 2 L O 2 per kg dry weight cereal grains is passed through said aqueous solution per h; c. finely dividing said germinated grains, while said germinated grains have a water content of at least 20%, with the proviso that said cereal grains do not have a water content below 20 at any time between steps b) and c); d. preparing an aqueous extract of said milled germinated grains, thereby producing an aqueous extract of the cereal. a. providing grains of a cereal; b. subjecting the cereal grains to a step of germination thereby obtaining germinated grains, wherein said step of germination comprises incubating said grains in an aqueous solution until the grains have a water content of at least 30%, wherein at least 2 L O 2 per kg dry weight cereal grains is passed through said aqueous solution per h; c. finely dividing said germinated grains, while said germinated grains have a water content of at least 20%, with the proviso that said cereal grains do not have a water content below 20 at any time between steps b) and c); d. preparing an aqueous extract of said milled germinated grains, thereby producing an aqueous extract of the cereal.
A delineator post to be used in a substantially upright position arranged at predetermined distances along edges of a road roads or highway, which delineator post comprises comprise a reflector surface for reflecting visible light from oncoming passing vehicles and an information tag adapted to be visible for an onboard vision system of such passing vehicles, characterized in that the reflector surface and the information tag are arranged together with a radar reflector on the outer surface of the top end of the delineator post, facing passing vehicles and in that the radar reflector on said surface facing oncoming passing vehicles is in form of a corner reflector disposed at a predetermined position in relation to the tag, this position to be known to said onboard vision system.