A suturing device, comprising: a head including a proximal end portion and a distal end portion, the distal end portion defining a first opening, the proximal end portion defining a second opening; a curved carrier member movably disposed at least partially within the distal end portion of the head, the carrier member being movable from a first position in which the carrier member is disposed substantially within the distal end portion of the head to a second position in which a first portion of the carrier member is moved out through the first opening and disposed adjacent the second opening and a second portion of the carrier member is disposed within the distal end portion of the head, the carrier member being configured to receive a needle coupled to a suture when in the first position and configured to pass the needle and a portion of the suture through a tissue when moved from the first position to the second position; characterized in that the proximal end portion of the head is configured to be removably coupled to a distal end portion of an elongate medical device configured to be disposed within a body lumen of a patient; and in that the suturing device further comprises an elongate flexible sheath coupled to the proximal end portion of the head; and a coupling member configured to removably couple the proximal end portion of the head to the distal end portion of the elongate medical device,; wherein when the proximal end portion of the head is coupled to the distal end portion of the elongate medical device, the elongate flexible sheath extends along an exterior of the elongate medical device. a head including a proximal end portion and a distal end portion, the distal end portion defining a first opening, the proximal end portion defining a second opening; a curved carrier member movably disposed at least partially within the distal end portion of the head, the carrier member being movable from a first position in which the carrier member is disposed substantially within the distal end portion of the head to a second position in which a first portion of the carrier member is moved out through the first opening and disposed adjacent the second opening and a second portion of the carrier member is disposed within the distal end portion of the head, the carrier member being configured to receive a needle coupled to a suture when in the first position and configured to pass the needle and a portion of the suture through a tissue when moved from the first position to the second position; characterized in that the proximal end portion of the head is configured to be removably coupled to a distal end portion of an elongate medical device configured to be disposed within a body lumen of a patient; and in that the suturing device further comprises an elongate flexible sheath coupled to the proximal end portion of the head; and a coupling member configured to removably couple the proximal end portion of the head to the distal end portion of the elongate medical device,; wherein when the proximal end portion of the head is coupled to the distal end portion of the elongate medical device, the elongate flexible sheath extends along an exterior of the elongate medical device.