An IV infusion set (10-21, 10-22, 10-23, 10-24), comprising: a patient access configured to connect to a vascular system of a patient; a source (40, 40a) of medical fluid; an infusion line having at least one first end configured to connect to the source (40, 40a) of medical fluid and at least one opposite second end configured to deliver the medical fluid towards the patient access, the infusion line defining at least a medical fluid path developing from the first end of the infusion line to the patient access, the second end of the infusion line being connected to the patient access, the source (40, 40a) of medical fluid being coupled to the first end of the infusion line and configured to supply medical fluid to the infusion line; an infusion apparatus (60, 60a) arranged on the infusion line and including a pump (62, 62a); a resistance element (130, 130a, 130a-1) configured to reflect pressure waves moving along the infusion line and including a flow restrictor to restrict flow of medical fluid along the infusion line through resistance element (130, 130a, 130a-1); a compliance element (120, 120a) configured to attenuate pressure variations of medical fluid the infusion line, the compliance element (120, 120a) being arranged downstream from the pump (62, 62a) and upstream from the resistance element (130, 130a) with respect to a direction of fluid flow along the infusion line from the medical fluid source (40, 40a) towards the patient access; characterized in that the IV infusion set (10-21, 10-22, 10-23, 10-24) further comprises: a sensor (102, 102a) configured to emit a pressure signal indicative of a pressure of a medical fluid in the infusion line; a control unit configured to receive the pressure signal and to determine a patient signal indicative of a vital signal of the patient based on the pressure signal, wherein said patient signal is indicative of one of a heart rate of a patient and a respiratory rate of a patient; and wherein the resistance element comprises a hollow body interposed along the infusion line to allow passage of the medical fluid, the hollow body having a fluid passage section smaller than a fluid passage section of the infusion line defining a section restriction for the medical fluid flow, wherein the resistance element is configured to primarily reflect pressure waves in fluid flow having frequencies below 3 Hz, wherein the sensor (102, 102a) is arranged on the infusion line at a position (LP, LPa) downstream from the resistance element (130, 130a) with respect to a direction of fluid flow along the infusion line from the medical fluid source (40, 40a) towards the patient access. a patient access configured to connect to a vascular system of a patient; a source (40, 40a) of medical fluid; an infusion line having at least one first end configured to connect to the source (40, 40a) of medical fluid and at least one opposite second end configured to deliver the medical fluid towards the patient access, the infusion line defining at least a medical fluid path developing from the first end of the infusion line to the patient access, the second end of the infusion line being connected to the patient access, the source (40, 40a) of medical fluid being coupled to the first end of the infusion line and configured to supply medical fluid to the infusion line; an infusion apparatus (60, 60a) arranged on the infusion line and including a pump (62, 62a); a resistance element (130, 130a, 130a-1) configured to reflect pressure waves moving along the infusion line and including a flow restrictor to restrict flow of medical fluid along the infusion line through resistance element (130, 130a, 130a-1); a compliance element (120, 120a) configured to attenuate pressure variations of medical fluid the infusion line, the compliance element (120, 120a) being arranged downstream from the pump (62, 62a) and upstream from the resistance element (130, 130a) with respect to a direction of fluid flow along the infusion line from the medical fluid source (40, 40a) towards the patient access; a sensor (102, 102a) configured to emit a pressure signal indicative of a pressure of a medical fluid in the infusion line; a control unit configured to receive the pressure signal and to determine a patient signal indicative of a vital signal of the patient based on the pressure signal, wherein said patient signal is indicative of one of a heart rate of a patient and a respiratory rate of a patient; and wherein the resistance element comprises a hollow body interposed along the infusion line to allow passage of the medical fluid, the hollow body having a fluid passage section smaller than a fluid passage section of the infusion line defining a section restriction for the medical fluid flow, wherein the resistance element is configured to primarily reflect pressure waves in fluid flow having frequencies below 3 Hz, wherein the sensor (102, 102a) is arranged on the infusion line at a position (LP, LPa) downstream from the resistance element (130, 130a) with respect to a direction of fluid flow along the infusion line from the medical fluid source (40, 40a) towards the patient access.