mhurhangee/ep-ind-claims huggingface dataset:
A chimeric antigen receptor, wherein the CAR comprises: i) an antigen-binding domain targeting a glycosylated CEA; ii) a transmembrane domain, and iii) an intracellular signaling domain comprising a costimulatory domain, wherein the antigen-binding domain targeting the glycosylated CEA comprises a heavy chain variable region and a light chain variable region, characterized in that the heavy chain variable region comprises: CDR-H1 set forth in SEQ ID NO: 13, CDR-H2 set forth in SEQ ID NO: 14, and CDR-H3 set forth in SEQ ID NO: 15; and the light chain variable region comprises: CDR-L1 set forth in SEQ ID NO: 16, CDR-L2 set forth in SEQ ID NO: 17, and CDR-L3 set forth in SEQ ID NO: 18. i) an antigen-binding domain targeting a glycosylated CEA; ii) a transmembrane domain, and iii) an intracellular signaling domain comprising a costimulatory domain,
An impeller specifically adapted to be mounted within a chamber of a centrifugal pump to rotate about a rotation axis X-X, the pump including a pump casing having the chamber therein, an inlet for delivering material to be pumped to the chamber and an outlet for discharging material from the chamber, the impeller including a front shroud, a back shroud and a plurality of pumping vanes therebetween, each pumping vane having a leading edge in the region of an impeller inlet and a trailing edge, wherein the front shroud has an arcuate inner face in the region of the impeller inlet, characterised in that: the arcuate inner face has a radius of curvature (R s) in the range from 0.05 to 0.16 of the outer diameter of the impeller (D 2), said back shroud having an inner main face and a nose having a curved profile with a nose apex in the region of the central axis which extends towards the front shroud, there being a curved transition region between the inner main face and the nose, wherein I nr, is the radius of curvature of the curved profile of the nose, the ratio I nr /D 2 being from 0.10 to 0.33.
Gas packaging installation comprising at least: - a buffer-capacity containing a pressurised gas, - a filling ramp for gas containers, - a main gas supply duct fluidly connecting the buffer-capacity to said at least one filling ramp, - a filling valve arranged on the main supply duct, - a control valve arranged on the supply duct between the buffer-capacity and the filling valve, - a bypass duct fluidly connected to the main duct upstream and downstream from the control valve, following the direction of circulation of the gas from the buffer-capacity towards said at least one ramp, - a gas non-return device arranged on the bypass duct enabling the passage of gas only in the direction of said at least one ramp, and and wherein the control valve is controlled by control means so as to be open when the filling valve is closed, or inversely, characterised in that: - the main supply duct is fluidly connected to a cryogenic pump supplied by a gas source, and - a manual isolation valve is arranged on the main duct between the buffer-capacity and the control valve. - a buffer-capacity containing a pressurised gas, - a filling ramp for gas containers, - a main gas supply duct fluidly connecting the buffer-capacity to said at least one filling ramp, - a filling valve arranged on the main supply duct, - a control valve arranged on the supply duct between the buffer-capacity and the filling valve, - a bypass duct fluidly connected to the main duct upstream and downstream from the control valve, following the direction of circulation of the gas from the buffer-capacity towards said at least one ramp, - a gas non-return device arranged on the bypass duct enabling the passage of gas only in the direction of said at least one ramp, and - the main supply duct is fluidly connected to a cryogenic pump supplied by a gas source, and - a manual isolation valve is arranged on the main duct between the buffer-capacity and the control valve.
A non-therapeutic method of stimulating regeneration of an epidermal appendage in the skin, which method comprises administering to said skin an effective amount of calreticulin or a functional fragment thereof.
An image filtering method, comprising: determining a filter coefficient of a chroma filter based on a filter coefficient of a luma filter, wherein filter coefficients of the luma filter present a first geometric distribution, filter coefficients of the chroma filter present a second geometric distribution; and respectively performing filtering processing on luma samples and chroma samples of a to-be-processed image by using the luma filter and the chroma filter; characterized in that a filter coefficient of the chroma filter at an edge of the second geometric distribution is calculated by using more than one filter coefficient of the luma filter at the first geometric distribution; wherein a filter coefficient distribution of the luma filter being the first geometric distribution is shown in the following table: wherein a filter coefficient distribution of the chroma filter being the second geometric distribution is shown in the following table: and wherein the filter coefficient of the chroma filter at an edge of the second geometric distribution comprises: Co, C1, C3, and C4, wherein a relationship between filter coefficients of the luma filter and filter coefficients of the chroma filter is as follows: C 6 = L 20; C 2 = L 12; C 5 = L 19; C 0 = L 1 + L 2 + L 3 + L 0 + L 6; C 1 = L 4 + L 5 + L 10 + L 11; C 3 = L 7 + L 8 + L 13 + L 14; and C 4 = L 9 + L 15 + L 16 + L 17 + L 18. determining a filter coefficient of a chroma filter based on a filter coefficient of a luma filter, wherein filter coefficients of the luma filter present a first geometric distribution, filter coefficients of the chroma filter present a second geometric distribution; and respectively performing filtering processing on luma samples and chroma samples of a to-be-processed image by using the luma filter and the chroma filter; a filter coefficient of the chroma filter at an edge of the second geometric distribution is calculated by using more than one filter coefficient of the luma filter at the first geometric distribution; wherein a filter coefficient distribution of the luma filter being the first geometric distribution is shown in the following table: wherein a filter coefficient distribution of the chroma filter being the second geometric distribution is shown in the following table: and wherein the filter coefficient of the chroma filter at an edge of the second geometric distribution comprises: Co, C1, C3, and C4, wherein a relationship between filter coefficients of the luma filter and filter coefficients of the chroma filter is as follows: C 6 = L 20; C 2 = L 12; C 5 = L 19; C 0 = L 1 + L 2 + L 3 + L 0 + L 6; C 1 = L 4 + L 5 + L 10 + L 11; C 3 = L 7 + L 8 + L 13 + L 14; and C 4 = L 9 + L 15 + L 16 + L 17 + L 18.
Lighting device for motor vehicle, the lighting device being designed to emit light in a main direction of emission and comprising at least: - a vane mounted with the ability to move in the lighting device, the vane having a panel on which at least one area light source is arranged: the or at least one area light source of which is an organic light emitting diode covering all or part of the surface of the panel of the corresponding vane, characterized in that the vane is mounted with the ability to move between a rest position and an emission position and in that the area light source of the or each vane is visible in the direction of emission in the rest position. - a vane mounted with the ability to move in the lighting device, the vane having a panel on which at least one area light source is arranged: the or at least one area light source of which is an organic light emitting diode covering all or part of the surface of the panel of the corresponding vane, characterized in that the vane is mounted with the ability to move between a rest position and an emission position and in that the area light source of the or each vane is visible in the direction of emission in the rest position.
Ducted axial fan, comprising a rotor rotatable around an axis X and comprising a plurality of blades; a duct suitable for defining a circular section channel developing in the axial direction around the rotor; wherein the duct comprises an annular seat circumferentially extending around the rotor and wherein the tips of the blades are at least partially received in the annular seat of the duct, and wherein at least one blade comprises a tip winglet and in that the tip winglet has a baffle extending at least partially in the axial direction characterised in that the baffle is received in the annular seat. a duct suitable for defining a circular section channel developing in the axial direction around the rotor; wherein the duct comprises an annular seat circumferentially extending around the rotor and wherein the tips of the blades are at least partially received in the annular seat of the duct, and wherein at least one blade comprises a tip winglet and in that the tip winglet has a baffle extending at least partially in the axial direction characterised in that the baffle is received in the annular seat.
Composition comprising: i) one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof; ii) a lipid fraction comprising at least one of docosahexaenoic acid (22:6; DHA), eicosapentaenoic acid (20:5; EPA) and docosapentaenoic acid (22:5; DPA), or esters thereof, in which the lipid fraction comprises less than 2 weight% of α-linolenic acid, calculated on the weight of all fatty acids; iii) choline, or salts or esters thereof; said composition further comprising at least one B complex vitamin; for use in the prevention or treatment of spinal cord injury. i) one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof; ii) a lipid fraction comprising at least one of docosahexaenoic acid (22:6; DHA), eicosapentaenoic acid (20:5; EPA) and docosapentaenoic acid (22:5; DPA), or esters thereof, in which the lipid fraction comprises less than 2 weight% of α-linolenic acid, calculated on the weight of all fatty acids; iii) choline, or salts or esters thereof; said composition further comprising at least one B complex vitamin;
An inductive drawing or feeding device for inductively drawing off or feeding in electrical energy/electricity by electric vehicles, wherein the inductive drawing or feeding device is connected to the power grid, the device comprising: a measuring means that is adapted to measure at least one physical parameter representing the electrical energy inductively transmitted through the associated drawing or feeding device; an identifier for identifying the owner of the connection of the inductive drawing or feeding device; and a comparing means that is configured to compare the at least one physical parameter measured at the connecting side with at least one physical parameter measured at the drawing or feeding side. a measuring means that is adapted to measure at least one physical parameter representing the electrical energy inductively transmitted through the associated drawing or feeding device; an identifier for identifying the owner of the connection of the inductive drawing or feeding device; and a comparing means that is configured to compare the at least one physical parameter measured at the connecting side with at least one physical parameter measured at the drawing or feeding side.
A method for transmitting a signal by a user equipment, UE, in a distributed antenna system, DAS, in which a plurality of antennas are distributedly disposed in a cell, the method comprising: receiving uplink antenna information from a base station, BS, the uplink antenna information indicating reception antennas of the BS for receiving an uplink signal; receiving downlink antenna information from the BS, the downlink antenna information indicating transmission antennas through which the BS transmits a downlink signal to the UE; controlling uplink power based on the uplink antenna information; and transmitting the uplink signal based on the uplink power control, wherein the uplink antenna information is discriminated from the downlink antenna information, wherein the transmission antennas indicated by the downlink antenna information comprise the reception antennas and at least one additional antenna, and wherein the uplink power is determined by using an average of path losses with respect to only reception antennas indicated by the uplink antenna information. receiving uplink antenna information from a base station, BS, the uplink antenna information indicating reception antennas of the BS for receiving an uplink signal; receiving downlink antenna information from the BS, the downlink antenna information indicating transmission antennas through which the BS transmits a downlink signal to the UE; controlling uplink power based on the uplink antenna information; and transmitting the uplink signal based on the uplink power control, wherein the uplink antenna information is discriminated from the downlink antenna information, wherein the transmission antennas indicated by the downlink antenna information comprise the reception antennas and at least one additional antenna, and wherein the uplink power is determined by using an average of path losses with respect to only reception antennas indicated by the uplink antenna information.
Copper alloy, which has undergone a thermomechanical treatment, consisting of (in wt.%): 15.5 to 36.0 % Zn, 0.3 to 3.0 % Sn, 0.5 to 0.7 % Fe, optionally also 0.001 to 0.4 % P, optionally also 0.01 to 0.1 % Al, optionally also in each case 0.01 to 0.3 % Ag, Mg, Zr, In, Co, Cr, Ti, Mn, optionally also 0.05 to 0.5 % Ni, the remainder copper and unavoidable impurities, the microstructure of the alloy comprising the following proportions of the main texture layers: at least 10 vol.% copper layer, at least 10 vol.% S/R layer, at least 5 vol.% brass layer, at least 2 vol.% cast layer, at least 2 vol.% 22RD cube layer, at least 0.5 vol.% cube layer, the proportions of the main texture layers being determined by means of X-ray diffraction by analysing the intensity distribution of the mean camber lines in the Euler space and the orientation distribution function, characterised in that finely distributed ferrous particles are contained in the alloy matrix, and in that the finely distributed ferrous particles having a diameter of less than 1 μm have a density of at least 0.5 particles per μm 2 in the alloy matrix. 15.5 to 36.0 % Zn, 0.3 to 3.0 % Sn, 0.5 to 0.7 % Fe, optionally also 0.001 to 0.4 % P, optionally also 0.01 to 0.1 % Al, optionally also in each case 0.01 to 0.3 % Ag, Mg, Zr, In, Co, Cr, Ti, Mn, optionally also 0.05 to 0.5 % Ni, at least 10 vol.% copper layer, at least 10 vol.% S/R layer, at least 5 vol.% brass layer, at least 2 vol.% cast layer, at least 2 vol.% 22RD cube layer, at least 0.5 vol.% cube layer,
Connecting head adapted to connect a compressed air dispensing device and an element in which to insufflate said compressed air, said connecting head comprising a connecting body adapted to be fastened to the dispensing device by means of a flexible duct, a duct being present within said body, and adapted to connect the flexible duct and the element within which to insufflate, which is connectable to the body by means of a valve with threaded end that is insertable into an outlet hole of the duct, an arm being also present, pivoted to the body at a pivoting axis of the arm perpendicular to the longitudinal axis of the body, an elastic means being also provided, acting on said arm in order to determine the mutual engagement between one portion thereof or an element connected to said arm, and the threaded end of the valve, this determining the reversible interlock fastening between the body and valve, said fastening being separable by an action on the arm, overcoming the action of the elastic means, wherein said arm presents a first portion (7") adapted to be in contact, in the position of rest, with the side of the thread of the threaded end of the valve, thereby determining the reversible engagement of the connecting body with said valve, said head being characterised in that the first portion (7") is sloped with respect to a second portion of the arm placed before the pivoting axis of the arm, in order to form an acute angle (α) with said second portion.
A method for improving ground comprising: - a step of drilling a drilling hole in a ground to be improved; - a step of moving a jet device in a vertical direction by rotating the same while the jet device is inserted into the drilling hole and a fluid for cutting the ground is injected from the jet device; and - a step of injecting a solidification material from the jet device from a discharge port at a lower end of the jet device, characterised in that said step of moving the jet device in a vertical direction by rotating the same while the fluid for cutting the ground is injected from the jet device comprises the steps of: o cutting the ground by injecting a partition forming material from a plurality of jetting ports at a portion which is vertically higher than the lower end portion of the jet device; and o after having cut the ground by injecting the partition forming material, injecting the solidification material from the discharge port while the ground is cut by injecting a stable liquid from the plurality of jetting ports, and in that the solidification material is a rich-mixed solidification material comprising a cement and having a ratio of water to cement in the range of 26% to 40%. - a step of drilling a drilling hole in a ground to be improved; - a step of moving a jet device in a vertical direction by rotating the same while the jet device is inserted into the drilling hole and a fluid for cutting the ground is injected from the jet device; and - a step of injecting a solidification material from the jet device from a discharge port at a lower end of the jet device, characterised in that said step of moving the jet device in a vertical direction by rotating the same while the fluid for cutting the ground is injected from the jet device comprises the steps of: o cutting the ground by injecting a partition forming material from a plurality of jetting ports at a portion which is vertically higher than the lower end portion of the jet device; and o after having cut the ground by injecting the partition forming material, injecting the solidification material from the discharge port while the ground is cut by injecting a stable liquid from the plurality of jetting ports, and in that the solidification material is a rich-mixed solidification material comprising a cement and having a ratio of water to cement in the range of 26% to 40%. o cutting the ground by injecting a partition forming material from a plurality of jetting ports at a portion which is vertically higher than the lower end portion of the jet device; and o after having cut the ground by injecting the partition forming material, injecting the solidification material from the discharge port
A magnet assembly for a Coriolis flow meter comprising at least one magnet and a magnet keeper including a substantially planar magnet receiving face for receiving the at least one magnet, with the magnet assembly being characterized by: a brazing that affixes the at least one magnet to the magnet receiving face of the magnet keeper; and a pole piece that is brazed to the at least one magnet, the pole piece including an aperture that provides an opening for brazing the pole piece to the at least one magnet. a brazing that affixes the at least one magnet to the magnet receiving face of the magnet keeper; and a pole piece that is brazed to the at least one magnet, the pole piece including an aperture that provides an opening for brazing the pole piece to the at least one magnet.
A horizontal axis wind turbine comprising a rotor with a hub, at least one blade, and a blade pitch system, the blade pitch system comprising for each blade - a blade bearing mounted between the hub and the blade, the bearing comprising two bearing rings (41, 42), one of which is fixed to the hub and the other of which is fixed to the blade, - a ring gear device fixed to a first of the bearing rings, and - a pinion mounted to a motor, where the motor is fixed to the hub if the first bearing ring is fixed to the blade and the motor is fixed to the blade if the first bearing ring is fixed to the hub, and where the pinion is engaged with the ring gear device, characterized in that - a connection between the first bearing ring and the ring gear device comprises a toothed interface. - a blade bearing mounted between the hub and the blade, the bearing comprising two bearing rings (41, 42), one of which is fixed to the hub and the other of which is fixed to the blade, - a ring gear device fixed to a first of the bearing rings, and - a pinion mounted to a motor, where the motor is fixed to the hub if the first bearing ring is fixed to the blade and the motor is fixed to the blade if the first bearing ring is fixed to the hub, and where the pinion is engaged with the ring gear device, - a connection between the first bearing ring and the ring gear device comprises a toothed interface.
Method of coating a substrate according to which there is continuously deposited on said substrate a layer of metal alloy based on zinc and comprising a predetermined proportion of magnesium of from 4% to 20% by weight by means of a vacuum deposition installation (1, 11, 21) comprising a device (7, 17) for coating using a vapour jet that makes it possible to project onto the substrate, at a sonic velocity, a vapour obtained by evaporation of a metal bath based on zinc and comprising initially a predetermined proportion of magnesium of from 30% to 55% by weight of magnesium, said initial proportion being kept constant in the course of deposition by way of means for adjustment of the composition of the bath of metal alloy which comprise means for supplying the evaporation means (3, 13) with molten metal alloy of controlled composition.
An apparatus of welding including an electrode comprising: a metal cylinder defining a weld end and a hollow interior, powdered feed materials positioned in the hollow interior and movable with respect to the metal cylinder towards the weld end of the electrode, a delivery means operable to move the powdered feed materials with respect to the metal cylinder, and an adherent flux coating surrounding the metal cylinder, and using an electrode holder defining an interior or opening having at least a portion thereof sized or adapted to facilitate the feeding of the powdered feed materials and/or the delivery means therethrough, wherein the electrode is held by the electrode holder opposite the weld end, wherein portions of the flux coating are removed or stripped in order for the electrode holder to hold the metal cylinder and to thereby establish a welding current connection during the welding operation. a metal cylinder defining a weld end and a hollow interior, powdered feed materials positioned in the hollow interior and movable with respect to the metal cylinder towards the weld end of the electrode, a delivery means operable to move the powdered feed materials with respect to the metal cylinder, and an adherent flux coating surrounding the metal cylinder, and using an electrode holder defining an interior or opening having at least a portion thereof sized or adapted to facilitate the feeding of the powdered feed materials and/or the delivery means therethrough, wherein the electrode is held by the electrode holder opposite the weld end, wherein portions of the flux coating are removed or stripped in order for the electrode holder to hold the metal cylinder and to thereby establish a welding current connection during the welding operation.