mhurhangee/ep-ind-claims huggingface dataset:
A binding molecule which is at least bispecific comprising a first and a second binding domain, wherein (a) the first binding domain is capable of binding to epitope cluster 3 and to epitope cluster 4 of BCMA; and (b) the second binding domain is capable of binding to CD3; and wherein epitope cluster 3 of BCMA corresponds to amino acid residues 24 to 41 of the sequence as depicted in SEQ ID NO: 1002, and epitope cluster 4 of BCMA corresponds to amino acid residues 42 to 54 of the sequence as depicted in SEQ ID NO: 1002, and wherein said binding molecule is a polypeptide. (a) the first binding domain is capable of binding to epitope cluster 3 and to epitope cluster 4 of BCMA; and (b) the second binding domain is capable of binding to CD3; and
A selection apparatus that selects a destination of data to be saved out of a plurality of tape recording apparatuses, comprising: a history information storage unit that stores history information about data lengths of past data saved in any of the plurality of tape recording apparatuses; a rank determination unit that determines a data length rank for the data to be saved based on the history information about the data lengths of the past data read out from the history information storage unit; a rank list storage unit that stores a performance rank list for the plurality of tape recording apparatuses; a selection unit that selects a tape recording apparatus for saving the data to be saved out of the plurality of tape recording apparatuses based on the performance rank list read out from the rank list storage unit and the data length rank determined by the rank determination unit so that the selection unit selects a tape recording apparatus with a high performance for the high-ranked data to be saved; and a transfer unit that transfers the data to be saved to the tape recording apparatus selected by the selection unit. a history information storage unit that stores history information about data lengths of past data saved in any of the plurality of tape recording apparatuses; a rank determination unit that determines a data length rank for the data to be saved based on the history information about the data lengths of the past data read out from the history information storage unit; a rank list storage unit that stores a performance rank list for the plurality of tape recording apparatuses; a selection unit that selects a tape recording apparatus for saving the data to be saved out of the plurality of tape recording apparatuses based on the performance rank list read out from the rank list storage unit and the data length rank determined by the rank determination unit so that the selection unit selects a tape recording apparatus with a high performance for the high-ranked data to be saved; and a transfer unit that transfers the data to be saved to the tape recording apparatus selected by the selection unit.
A blade assembly comprising: a first elongated blade and a second elongated blade, wherein the first elongated blade and the second elongated blade each comprise a trimming portion and a high-capacity trimming portion, the trimming portion of each of the first elongated blade and the second elongated blade comprising a set of trimming teeth, and the high-capacity trimming portion of each of the first elongated blade and the second elongated blade comprising one or more high-capacity trimming teeth that are longer than the trimming teeth, and wherein the high-capacity trimming portion of the first elongated blade or the second elongated blade further comprises a first guide tooth, the first guide tooth being disposed on a first side of the one or more high-capacity trimming teeth of the first elongated blade or the second elongated blade, wherein the high-capacity trimming portion of the first elongated blade or the second elongated blade further comprises a second guide tooth, the second guide tooth being disposed on a second side of the one or more high-capacity trimming teeth of the first elongated blade or the second elongated blade, and wherein the first guide tooth and the second guide tooth are longer than the one or more high-capacity trimming teeth of the first elongated blade and the second elongated blade. a first elongated blade and a second elongated blade, wherein the first elongated blade and the second elongated blade each comprise a trimming portion and a high-capacity trimming portion, the trimming portion of each of the first elongated blade and the second elongated blade comprising a set of trimming teeth, and the high-capacity trimming portion of each of the first elongated blade and the second elongated blade comprising one or more high-capacity trimming teeth that are longer than the trimming teeth, and wherein the high-capacity trimming portion of the first elongated blade or the second elongated blade further comprises a first guide tooth, the first guide tooth being disposed on a first side of the one or more high-capacity trimming teeth of the first elongated blade or the second elongated blade, wherein the high-capacity trimming portion of the first elongated blade or the second elongated blade further comprises a second guide tooth, the second guide tooth being disposed on a second side of the one or more high-capacity trimming teeth of the first elongated blade or the second elongated blade, and wherein the first guide tooth and the second guide tooth are longer than the one or more high-capacity trimming teeth of the first elongated blade and the second elongated blade.
Method for the wireless reading-out of different identification elements, wherein a read-out unit receives a signal, which includes a base sequence and an identification sequence, from an identification element and a raster for evaluating the identification sequence is generated from the base sequence, characterised in that the base sequence contains class information which is independent of the base and on the basis of which the raster for evaluating the identification sequence is adapted.
A reference circuit, comprising: a semiconductor device comprising first and second diodes (MGLD1, MGLD2, 44) each of which has a gate, a n-type semiconductor region, and a gate insulator layer interposed between the gate and the doped semiconductor region of the diode associated therewith, wherein the gate insulator is operable to allow carriers to tunnel between the n-type semiconductor region and the gate of the diode associated therewith; and a biasing circuit connected to the first and second diodes (MGLD1, MGLD2, 44) and having an output that is operable to supply a reference voltage (V OUT); characterized in that the gate of the first diode (MGLD1, 44) forms an anode for the first diode and the gate of the second diode (MGLD2, 44) forms an anode for the second diode, and in that the anodes are connected to the biasing circuit; the first and second diodes (MGLD1, MGLD2, 44) each further comprises an n+type region within the n-type semiconductor region that serves as a cathode; wherein a ground terminal is connected to the cathode of the first diode (MGLD1) and to the cathode of the second diode (MGLD2). a semiconductor device comprising first and second diodes (MGLD1, MGLD2, 44) each of which has a gate, a n-type semiconductor region, and a gate insulator layer interposed between the gate and the doped semiconductor region of the diode associated therewith, wherein the gate insulator is operable to allow carriers to tunnel between the n-type semiconductor region and the gate of the diode associated therewith; and a biasing circuit connected to the first and second diodes (MGLD1, MGLD2, 44) and having an output that is operable to supply a reference voltage (V OUT); the gate of the first diode (MGLD1, 44) forms an anode for the first diode and the gate of the second diode (MGLD2, 44) forms an anode for the second diode, and in that the anodes are connected to the biasing circuit; the first and second diodes (MGLD1, MGLD2, 44) each further comprises an n+type region within the n-type semiconductor region that serves as a cathode; wherein a ground terminal is connected to the cathode of the first diode (MGLD1) and to the cathode of the second diode (MGLD2).
Double seat valve for aseptic lines for product with - a valve housing, - two line ports (6, 7) arranged on said valve housing for connecting said aseptic lines for product to said valve housing, - two valve seats (23, 24) which are formed between said line ports (6, 7) on said valve housing and define a safety chamber formed therebetween for leaks against said line ports (6, 7), - a first closure element which is actuatable by a first valve stem and acts against one of said two valve seats, and - a second closure element which is actuatable by a second valve stem and acts against the other of said two valve seats, where said first valve stem at least in sections surrounds said second valve stem so that both are movable independently along a valve axis, and where said first valve stem is connected via a diaphragm seal, which is formed to have a ring shape around said valve axis, to said second valve stem for sealing against said safety chamber, characterized in that an outer fastening portion of said ring-shaped diaphragm seal is bent inwardly toward said valve axis by a bending angle of more than 90°, so that it abuts against a tapered surface of a first fastening element. - a valve housing, - two line ports (6, 7) arranged on said valve housing for connecting said aseptic lines for product to said valve housing, - two valve seats (23, 24) which are formed between said line ports (6, 7) on said valve housing and define a safety chamber formed therebetween for leaks against said line ports (6, 7), - a first closure element which is actuatable by a first valve stem and acts against one of said two valve seats, and - a second closure element which is actuatable by a second valve stem and acts against the other of said two valve seats,
A seed transportation system comprising a rotatable wheel with at least one seed support for holding a seed, wherein said at least one seed support has one or more fixed support structures configured to restrict movement of the seed in a circumferential direction relative to the rotatable wheel and in a direction away from an axis of rotation of the rotatable wheel, wherein said at least one seed support has an access opening in its radially outer side, said access opening permitting access to the seed, characterized in that said access opening is a tangential groove, said tangential groove permitting access to the seed along a secant line cutting the circumference of the rotatable wheel.
A Cu-Al-Mn-based alloy having a composition consisting of 3 to 10% by mass of Al; 5 to 20% by mass of Mn; 0 to 1% by mass of Ni; and optionally 0.001 to 10% by mass in total of at least one element selected from the group consisting of Fe, Ti, V, Cr, Si, Nb, Mo, W, Sn, Mg, P, Be, Sb, Cd, As, Zr, Zn, B, C, Ag and misch metal; with the balance being Cu and unavoidable impurities, having superelastic characteristics, the residual strain after 6% deformation is 1.0% or less, wherein the proportion occupied by a β phase in the recrystallization structure is 90% or more, wherein 70% or more of the crystal grains are within a range of 0° to 50° in a deviation angle from <001> orientation of a crystalline orientation measured in a working direction by electron back-scatter diffraction patterning.
Nozzle plate for an axially damping hydraulic bearing, the nozzle plate having a channel disc with a channel for connecting working and compensating chambers (6, 8) of the hydraulic bearing, wherein the channel disc is fixable in a non-rotatable manner in the hydraulic bearing, wherein the channel is delimited on one side by a cover disc which is fixed in a non-rotatable manner in one of various radial positions with respect to the channel disc, and wherein the cover disc has an opening which is arranged at a predeterminable radial position above the channel and forms an inlet opening or outlet opening for a fluid damping means to enter the channel or leave the channel, characterised in that the cross-sectional area of the channel changes over the length of the channel.
A mining plow configured to be used in a longwall mining system in an underground mine, comprising: a plow body constructed to be guided at a conveyor, the plow body having a first end with a first pivot pin and a second end with a second pivot pin, the second end opposing the first end; a first cutting bit carrier pivotably supported on the first pivot pin; a second cutting bit carrier pivotably supported on the second pivot pin; a central roof cutting bit carrier assembly at least partially arranged between the first cutting bit carrier and the second cutting bit carrier; and a pushrod displaceably arranged within the plow body to form a positive coupling between the first cutting bit carrier and the second cutting bit carrier, the pushrod being arch-shaped to pass around the central roof cutting bit carrier assembly. a plow body constructed to be guided at a conveyor, the plow body having a first end with a first pivot pin and a second end with a second pivot pin, the second end opposing the first end; a first cutting bit carrier pivotably supported on the first pivot pin; a second cutting bit carrier pivotably supported on the second pivot pin; a central roof cutting bit carrier assembly at least partially arranged between the first cutting bit carrier and the second cutting bit carrier; and a pushrod displaceably arranged within the plow body to form a positive coupling between the first cutting bit carrier and the second cutting bit carrier, the pushrod being arch-shaped to pass around the central roof cutting bit carrier assembly.
A compression screw driver system comprising: a drive member including a shaft extending from a proximal end to a distal end with a drive tip defined on the distal end; a drive selection member positioned about the shaft and secured thereto such that the drive selection member rotates with the shaft and is axially moveable along the shaft between an engagement position and a disengaged position, a distal portion of the drive selection member defining a first engagement structure; and a compression sleeve having a tubular body extending from a proximal end to a distal end with a through passage therethrough is positioned over the distal end of the shaft with threads within the through passage threadably engaging threads on the shaft, the proximal end of the compression sleeve defines a second engagement structure which complements the first engagement structure and the distal end of the compression sleeve defines a contact surface, wherein in the engagement position the first and second engagement structures are engaged and the compression sleeve rotates with the drive member and in the disengaged position the first and second engagement structures are disengaged and the compression sleeve remains stationary while the drive member rotates. a drive member including a shaft extending from a proximal end to a distal end with a drive tip defined on the distal end; a drive selection member positioned about the shaft and secured thereto such that the drive selection member rotates with the shaft and is axially moveable along the shaft between an engagement position and a disengaged position, a distal portion of the drive selection member defining a first engagement structure; and a compression sleeve having a tubular body extending from a proximal end to a distal end with a through passage therethrough is positioned over the distal end of the shaft with threads within the through passage threadably engaging threads on the shaft, the proximal end of the compression sleeve defines a second engagement structure which complements the first engagement structure and the distal end of the compression sleeve defines a contact surface, wherein in the engagement position the first and second engagement structures are engaged and the compression sleeve rotates with the drive member and in the disengaged position the first and second engagement structures are disengaged and the compression sleeve remains stationary while the drive member rotates.
A method for isolating, enriching or concentrating of exosomes, comprising the steps (i) spinning down an aqueous biological sample selected from the group consisting of a bodily fluid sample or a cell culture medium sample to remove cells and cell debris; (ii) collecting the supernatant and providing this as sample to be incubated; (iii) incubating the supernatant of the aqueous biological sample comprising exosomes obtained in step (ii) with a reactant comprising a hydrophilic target domain covalently linked to a lipophilic membrane anchor domain, wherein the lipophilic membrane anchor domain becomes integrated into the lipid double layer of the membrane and wherein the hydrophilic target domain becomes exposed to the surrounding aqueous sample fluid, wherein the hydrophilic target domain of the reactant carries an EX-tag, wherein the EX-tag is a protein or peptide tag (iv) isolating the membrane modified exosomes from the sample fluid and/or excessive reactants, with the use of said tag. (i) spinning down an aqueous biological sample selected from the group consisting of a bodily fluid sample or a cell culture medium sample to remove cells and cell debris; (ii) collecting the supernatant and providing this as sample to be incubated; (iii) incubating the supernatant of the aqueous biological sample comprising exosomes obtained in step (ii) with a reactant comprising a hydrophilic target domain covalently linked to a lipophilic membrane anchor domain, wherein the lipophilic membrane anchor domain becomes integrated into the lipid double layer of the membrane and wherein the hydrophilic target domain becomes exposed to the surrounding aqueous sample fluid, wherein the hydrophilic target domain of the reactant carries an EX-tag, wherein the EX-tag is a protein or peptide tag (iv) isolating the membrane modified exosomes from the sample fluid and/or excessive reactants, with the use of said tag.
Capsule (1, 11, 20) for preparing beverages, comprising: - an essentially closed housing (12, 27) which is at least partially filled with a substance to be extracted and/or dissolved, such as ground coffee, for preparing a beverage, wherein the housing (12, 27) is essentially closed, wherein the housing (12, 27) is defined at least by a peripheral wall (12b, 29), an end side (12a, 28) connected to the peripheral wall (12b, 29), and a laterally protruding engaging edge (12c, 30) connected to the peripheral wall (12b, 29) at a distance from the end side (12a, 28) in order to allow the capsule (1, 11, 20) to be clamped into a capsule holder of a device for preparing beverages; and - at least one essentially closed closing element (2, 13, 21, 40) connected to the laterally protruding engaging edge (12c, 30) for sealing the substance into the capsule (1, 11, 20) in order to preserve it, characterized in that at least a part of the closing element (2, 13, 21, 40) is composed of a laminated film (2, 13, 21, 40) comprising a plurality of polymer layers (3, 5, 6, 13a, 13c, 13d, 13f, 21a-21f, 40a, 40b, 40c), which film (2, 13, 21, 40) comprises at least one polymer oxygen barrier layer (5, 13d, 21d, 40b), which barrier layer (5, 13d, 21d, 40b) is essentially impermeable to oxygen, and which film (2, 13, 21, 40) comprises at least one polymer carrier layer (6, 13a, 13c, 13f, 21a, 21c, 21f) connected to the oxygen barrier layer (5, 13d, 21d, 40c), wherein at least one carrier layer (6, 13a, 13c, 13f, 21a, 21c, 21f, 40a, 40c) is provided with at least one weakened area (7, 23), and wherein the film (2, 13, 21, 40) comprises at least one shielding layer connected to a side of the oxygen barrier layer (5, 13d, 21d, 40b) facing away from the substance, wherein the shielding layer is closed, and wherein the shielding layer preferably forms a moisture barrier layer. - an essentially closed housing (12, 27) which is at least partially filled with a substance to be extracted and/or dissolved, such as ground coffee, for preparing a beverage, wherein the housing (12, 27) is essentially closed, wherein the housing (12, 27) is defined at least by a peripheral wall (12b, 29), an end side (12a, 28) connected to the peripheral wall (12b, 29), and a laterally protruding engaging edge (12c, 30) connected to the peripheral wall (12b, 29) at a distance from the end side (12a, 28) in order to allow the capsule (1, 11, 20) to be clamped into a capsule holder of a device for preparing beverages; and - at least one essentially closed closing element (2, 13, 21, 40) connected to the laterally protruding engaging edge (12c, 30) for sealing the substance into the capsule (1, 11, 20) in order to preserve it,
A haymaking machine provided with a drawbar whose front end is fastened pivotably about a substantially upwardly orientated connecting axis to a trestle extending substantially transverse to the drawbar, and whose rear end is provided with a supporting wheel set comprising two wheels (5, 6) disposed on either side of the drawbar, a pair of drivable crop processing members (7, 8) arranged on either side of the drawbar and rotatable about substantially upwardly orientated rotor axes being disposed between said front end and rear end, the orientation of the wheels (5, 6) relative to the drawbar being adjustable by means of a steering device, the steering device comprising a steering rod which is pivotably connected both with the trestle and with the wheel set, and a hydraulic cylinder which has one end connected with the steering rod and its other end with the wheel set, characterized in that the haymaking machine is provided with a carrier frame connected with the drawbar for carrying a crop processing member (7, 8), the swath board being fastened to a swath board frame that is pivotably connected with the carrier frame about a substantially horizontally extending axis, and with a pivoting plate provided with a slot by means of which the orientation of the swath board is adjustable relative to the direction of travel of the haymaking machine.
A firearm for transmitting data to and from an accessory (42, 102, 104); the firearm comprising a master CPU connected to a inductively powering rail, characterized in that the master CPU is further connected to a microcontroller of an inductively powering side rail units (94, 96), said side rail units (94,96) communicating with master CPU though a communication bus permitting the master CPU to determine at least one of the information data of the group consisting of: when an accessory has been connected, when it is disconnected; GPS feedback; data sent to an external data transfer module and displayed to the user; indication of the range to a target communicated to an accessory.