Radially collapsible frame (1, 100, 200) for a prosthetic valve, the frame (1, 100, 200) comprising: - an outflow end region (3, 103, 203) at a proximal end of the frame (1, 100, 200) and an inflow end region (2, 102,202) at a distal end of the frame (1, 100, 200), opposite to the outflow end region (3, 103,203); - at least two radially spaced commissure attachment regions (10, 10', 10") located at the outflow end region (3, 103,203) of the frame (1, 100, 200) and being configured to receive commissure edges of at least two prosthetic valve leaflets; - a cell structure (30, 130, 230) composed of a plurality of lattice cells being arranged radially around a flow axis of the frame (1, 100, 200) and connecting the at least two commissure attachment regions (10, 10', 10", 110, 110', 110", 210, 210', 210"); - at least one anchoring/positioning arch (20, 20', 20", 120, 120', 120", 220, 220', 220"), wherein said at least one anchoring/positioning arch (20, 20', 20", 120, 120', 120", 220, 220', 220") is located along the same section of the frame flow axis as the cell structure (30, 130, 230) but radially outwardly distanced therefrom, so as to radially overlap the cell structure (30, 130, 230) at least partially in the expanded configuration, wherein the frame further comprises a plurality of circumferentially arranged retaining arches (40, 40', 40"), each including first and second arms (40a, 40a', 40a", 40b, 40b', 40b") joined to one another at a distal end of the retaining arches (40, 40', 40"), the two arms being joined by a rounded structure, wherein the cell structure comprises a first cell region (31, 31', 31") composed of a plurality of first cells, a plurality of first cells being arranged between the respective first and second arms (40a, 40a', 40a", 40b, 40b', 40b") of each retaining arch (40, 40', 40"), and a second cell region (32, 32', 32") composed of a plurality of second cells, said second cells being arranged between adjacent arms of two neighboring retaining arches (40, 40', 40"), and wherein the frame exhibits a structure integrally cut from a portion of a tube, in particular from a small metal tube. - an outflow end region (3, 103, 203) at a proximal end of the frame (1, 100, 200) and an inflow end region (2, 102,202) at a distal end of the frame (1, 100, 200), opposite to the outflow end region (3, 103,203); - at least two radially spaced commissure attachment regions (10, 10', 10") located at the outflow end region (3, 103,203) of the frame (1, 100, 200) and being configured to receive commissure edges of at least two prosthetic valve leaflets; - a cell structure (30, 130, 230) composed of a plurality of lattice cells being arranged radially around a flow axis of the frame (1, 100, 200) and connecting the at least two commissure attachment regions (10, 10', 10", 110, 110', 110", 210, 210', 210"); - at least one anchoring/positioning arch (20, 20', 20", 120, 120', 120", 220, 220', 220"), wherein said at least one anchoring/positioning arch (20, 20', 20", 120, 120', 120", 220, 220', 220") is located along the same section of the frame flow axis as the cell structure (30, 130, 230) but radially outwardly distanced therefrom, so as to radially overlap the cell structure (30, 130, 230) at least partially in the expanded configuration, wherein the frame further comprises a plurality of circumferentially arranged retaining arches (40, 40', 40"), each including first and second arms (40a, 40a', 40a", 40b, 40b', 40b") joined to one another at a distal end of the retaining arches (40, 40', 40"), the two arms being joined by a rounded structure, wherein the cell structure comprises a first cell region (31, 31', 31") composed of a plurality of first cells, a plurality of first cells being arranged between the respective first and second arms (40a, 40a', 40a", 40b, 40b', 40b") of each retaining arch (40, 40', 40"), and a second cell region (32, 32', 32") composed of a plurality of second cells, said second cells being arranged between adjacent arms of two neighboring retaining arches (40, 40', 40"), and wherein the frame exhibits a structure integrally cut from a portion of a tube, in particular from a small metal tube.