mhurhangee/ep-ind-claims huggingface dataset:
A transcatheter mitral valve replacement system for a heart, comprising: a delivery sheath having a distal end portion insertable into a left atrium; a delivery catheter slidably disposed within the delivery sheath; and a two-part prosthetic mitral valve coupled to the delivery catheter by one or more control wires, the two-part prosthetic mitral valve configured to be disposed within the delivery sheath in a radially compressed condition and to radially self-expand when the two-part prosthetic mitral valve is outside of the delivery sheath and is unconstrained by the one or more control wires, the two-part prosthetic mitral valve comprising: a valve assembly including an expandable valve frame and a tri-leaflet occluder; an anchor assembly separately expandable from the valve assembly and defining an interior space within which the valve assembly is nested while the two-part prosthetic mitral valve is within the delivery sheath for simultaneous deployment from the delivery sheath; and a pusher catheter slidably disposed within the delivery catheter and releasably coupled to the anchor assembly. a delivery sheath having a distal end portion insertable into a left atrium; a delivery catheter slidably disposed within the delivery sheath; and a two-part prosthetic mitral valve coupled to the delivery catheter by one or more control wires, the two-part prosthetic mitral valve configured to be disposed within the delivery sheath in a radially compressed condition and to radially self-expand when the two-part prosthetic mitral valve is outside of the delivery sheath and is unconstrained by the one or more control wires, the two-part prosthetic mitral valve comprising: a valve assembly including an expandable valve frame and a tri-leaflet occluder; an anchor assembly separately expandable from the valve assembly and defining an interior space within which the valve assembly is nested while the two-part prosthetic mitral valve is within the delivery sheath for simultaneous deployment from the delivery sheath; and a pusher catheter slidably disposed within the delivery catheter and releasably coupled to the anchor assembly. a valve assembly including an expandable valve frame and a tri-leaflet occluder; an anchor assembly separately expandable from the valve assembly and defining an interior space within which the valve assembly is nested while the two-part prosthetic mitral valve is within the delivery sheath for simultaneous deployment from the delivery sheath; and a pusher catheter slidably disposed within the delivery catheter and releasably coupled to the anchor assembly.
A process for preparing polyisocyanates by catalytic oligomerization of isocyanates, which comprises the steps a) reaction of at least one isocyanate under suitable reaction conditions in the presence of at least one compound which catalyzes the conversion of the isocyanate into the desired polyisocyanate and optionally in the presence of at least one alcohol and optionally at least one solvent, b) addition of at least one compound which is able to deactivate the catalyst used in step a) to the reaction mixture when the desired conversion has been reached in step a), and c) separation of the unreacted isocyanate from the resulting reaction mixture, wherein the compound has the formula where R 1 and R 2 are each, independently of one another, C 1 - C 20 -alkyl, C 6 - C 12 -aryl or C 5 - C 12 -cycloalkyl which may optionally be substituted by aryl, alkyl, aryloxy, alkyloxy, heteroatoms and/or heterocycles, R 2 is additionally hydrogen and R 1 and R 2 may together with the group X- -NH also form a 5- to 12-membered ring in which R 1 and R 2 together form an optionally substituted divalent C 2 - C 9 -alkylene radical which can also be part of an arylene or cycloalkylene radical, Z is oxygen or sulfur, X is oxygen, sulfur, imino or substituted imino (NR 3) and R 3 is C 1 - C 4 -alkyl, where the radical R 1 has at least one mercapto, amino, monosubstituted amino or hydroxyl group. a) reaction of at least one isocyanate under suitable reaction conditions in the presence of at least one compound which catalyzes the conversion of the isocyanate into the desired polyisocyanate and optionally in the presence of at least one alcohol and optionally at least one solvent, b) addition of at least one compound which is able to deactivate the catalyst used in step a) to the reaction mixture when the desired conversion has been reached in step a), and c) separation of the unreacted isocyanate from the resulting reaction mixture, R 1 and R 2 are each, independently of one another, C 1 - C 20 -alkyl, C 6 - C 12 -aryl or C 5 - C 12 -cycloalkyl which may optionally be substituted by aryl, alkyl, aryloxy, alkyloxy, heteroatoms and/or heterocycles, R 2 is additionally hydrogen and R 1 and R 2 may together with the group X- -NH also form a 5- to 12-membered ring in which R 1 and R 2 together form an optionally substituted divalent C 2 - C 9 -alkylene radical which can also be part of an arylene or cycloalkylene radical, Z is oxygen or sulfur, X is oxygen, sulfur, imino or substituted imino (NR 3) and R 3 is C 1 - C 4 -alkyl, where the radical R 1 has at least one mercapto, amino, monosubstituted amino or hydroxyl group.
A unit for applying at least one opening device (4, 4a) onto an open sleeve destined to form a sealed package, comprising: - a sonotrode for sealing the opening device (4, 4a) onto a hole of a packaging material destined to from the sealed package, and - an anvil, which is adapted to co-operate with said opening device (4, 4a), on the opposite side of said sonotrode, during the sealing of said opening device (4, 4a) to said packaging material of said sleeve, the anvil comprising a receiving element adapted to insert said opening device (4, 4a) into said hole; the sonotrode comprising: - a sealing surface adapted to cooperate with said packaging material in order to seal said opening device (4, 4a) to said packaging material; - a cavity bounded by an opening of said sealing surface and adapted to receive said opening device (4, 4a); - a ring made in elastomeric material, partially protruding inside said cavity, and adapted to center a first axis of said opening device (4, 4a) on a second axis of said sonotrode, wherein said ring is adapted to contact, in use, a portion (9, 10) of said opening device (4, 4a); said sealing surface being adapted to contact, in use, a side of said packaging material which defines the outer side of said package, wherein said ring comprises, on the side of said second axis, a wall which tapers on the opposite side of said opening and is adapted to contact said opening device (4, 4a), and said wall comprises, at least when said ring contacts, in use, said opening device (4, 4a) and is elastically deformed by said opening device (4, 4a), proceeding from said opening towards the opposite side to said opening: - a first portion angled at a first angle with respect to said second axis; and - a second portion angled at a second angle with respect to said second axis, and said second angle is smaller than said first angle. - a sonotrode for sealing the opening device (4, 4a) onto a hole of a packaging material destined to from the sealed package, and - an anvil, which is adapted to co-operate with said opening device (4, 4a), on the opposite side of said sonotrode, during the sealing of said opening device (4, 4a) to said packaging material of said sleeve, the anvil comprising a receiving element adapted to insert said opening device (4, 4a) into said hole; - a sealing surface adapted to cooperate with said packaging material in order to seal said opening device (4, 4a) to said packaging material; - a cavity bounded by an opening of said sealing surface and adapted to receive said opening device (4, 4a); - a ring made in elastomeric material, partially protruding inside said cavity, and adapted to center a first axis of said opening device (4, 4a) on a second axis of said sonotrode, - a first portion angled at a first angle with respect to said second axis; and - a second portion angled at a second angle with respect to said second axis, and
A method of determining mRNA copy number in a test sample, the method comprising: a. determining a number of cells in the test sample; b. determining an amount of a test mRNA in the test sample by an RNA assay using a standard function, wherein the standard function represents the relationship between a known assay input and the resulting assay output; and, c. determining the copy number of the mRNA in the cells based on the number of cells and the determined amount of test mRNA. a. determining a number of cells in the test sample; b. determining an amount of a test mRNA in the test sample by an RNA assay using a standard function, wherein the standard function represents the relationship between a known assay input and the resulting assay output; and, c. determining the copy number of the mRNA in the cells based on the number of cells and the determined amount of test mRNA.
A truck, comprising a chassis with two spaced-apart frame rails running in a longitudinal direction of the chassis, between a front end and a rear end of the truck, a front wheel assembly with an axle attached to the frame rails, and an opposed-piston engine supported on the frame rails, wherein the opposed-piston engine includes a cylinder assembly with a row of cylinders disposed in space between the rails and running in the longitudinal direction, wherein the cylinder assembly has a longitudinal axis running through the space between the rails; characterized in that: the opposed-piston engine is positioned between the front end and the axle; and the cylinder assembly is oriented vertically with respect to the longitudinal direction. the opposed-piston engine is positioned between the front end and the axle; and the cylinder assembly is oriented vertically with respect to the longitudinal direction.
An optical system for an apparatus for processing thin-film layers, comprising: - a plurality of optical fibers for guiding light, in particular laser light, - at least one optical light-incoupling device for coupling the light into the optical fibers, and - an optical imaging device for generating in an illumination plane an illumination line that is formed by light beams (14'; 40; 40a, 40b) emanating from the optical fibers, and that has a long axis and a short axis, characterized in that each of the optical fiber has a rectangular cross-section with a short fiber axis (x) and a long fiber axis (y) and that the optical imaging device comprises an anamorphic lens that is configured to focus the light beams (40a, 40b) emanating from the optical fibers with respect to the short fiber axis (x) onto the short axis of the illumination line and to superimpose them in a homogenized manner relative to the long fiber axis (y) in the illumination line. - a plurality of optical fibers for guiding light, in particular laser light, - at least one optical light-incoupling device for coupling the light into the optical fibers, and - an optical imaging device for generating in an illumination plane an illumination line that is formed by light beams (14'; 40; 40a, 40b) emanating from the optical fibers, and that has a long axis and a short axis,
An orally-administrable composition comprising CTB-Exendin-4 expressed in a chloroplast; and rubisco for use in a method for retarding the development of or treating diabetes in a subject in need thereof.
Method for testing a humidity sensor, comprising the steps of: at a first temperature measuring a first relative humidity (Φ1) by the humidity sensor, calculating a first value based on the measured first relative humidity (Φ1) and based on a saturated vapour pressure at the first temperature, at a second temperature measuring a second relative humidity (Φ2) by the humidity sensor, calculating a second value based on the measured second relative humidity (Φ2) and based on a saturated vapour pressure at the second temperature, which values (V1, V2) do not vary with varying temperatures in case the humidity sensor is not affected in its sensing capabilities, and evaluating the first value and the second value relative to each other, wherein evaluating the first value and the second value relative to each other includes determining a deviation (|V2-V1|) between the first value and the second value, comparing the deviation (|V2-V1|) with a threshold, and issuing a signal when the deviation (|V2-V1|) exceeds the threshold. at a first temperature measuring a first relative humidity (Φ1) by the humidity sensor, calculating a first value based on the measured first relative humidity (Φ1) and based on a saturated vapour pressure at the first temperature, at a second temperature measuring a second relative humidity (Φ2) by the humidity sensor, calculating a second value based on the measured second relative humidity (Φ2) and based on a saturated vapour pressure at the second temperature, which values (V1, V2) do not vary with varying temperatures in case the humidity sensor is not affected in its sensing capabilities, and evaluating the first value and the second value relative to each other, wherein evaluating the first value and the second value relative to each other includes determining a deviation (|V2-V1|) between the first value and the second value, comparing the deviation (|V2-V1|) with a threshold, and issuing a signal when the deviation (|V2-V1|) exceeds the threshold.
Balance-spring stud used for fixing a last turn on the outside of a spiral spring for a timepiece movement, this balance-spring stud comprising a base that lies in a plane, a first arm and a second arm that extend from said plane being free at their end opposite to the base, the first and second arms (6, 8) being separated from one another by a gap in which the free end of the last turn on the outside of the spiral spring which is intended to be trapped in a hardened spot of glue is intended to be housed, at least one of the first and second arms (6, 8) being provided with a stop means arranged to prevent the spot of hardened glue in which the free end of the last turn on the outside of the spiral spring is intended to be trapped from being released from the gap in which said spot of hardened glue is housed when this spot of hardened glue no longer adheres to the balance-spring stud, characterised in that at least the first arm comprises a groove at a distance from the free end thereof, this groove lying in a plane that forms an angle with the plane of the base and which delimits, for at least the first arm, a hook forming a support surface that holds the spot of hardened glue.
A wind turbine nacelle comprising a nacelle cover forming a nacelle inner space, wherein the nacelle cover includes: a fixed cover which includes a side wall portion of the nacelle cover; a movable cover which includes at least a part of a ceiling portion of the nacelle cover and is attached to the fixed cover in such a manner as to be liftable in a vertical direction with respect to the fixed cover; and an opening formed in the nacelle through which a device disposed in the nacelle inner space can be lifted and lowered between the nacelle inner space and a nacelle outer space using a temporary lifting and lowering device, wherein, in use, when the movable cover is lifted in the vertical direction with respect to the fixed cover into a position above the fixed cover, an expanded space (S') as the nacelle inner space is formed below the lifted movable cover such that the expanded space (S') is covered with the movable cover on the upper side, and wherein the movable cover is configured such that, when, in use, the movable cover is lifted in the vertical direction with respect to the fixed cover into the position above the fixed cover, the temporary lifting and lowering device is disposed in the expanded space (S') formed by the moveable cover in the vertical direction with respect to the fixed cover in use of the temporary lifting and lowering device. a fixed cover which includes a side wall portion of the nacelle cover; a movable cover which includes at least a part of a ceiling portion of the nacelle cover and is attached to the fixed cover in such a manner as to be liftable in a vertical direction with respect to the fixed cover; and an opening formed in the nacelle through which a device disposed in the nacelle inner space can be lifted and lowered between the nacelle inner space and a nacelle outer space using a temporary lifting and lowering device, wherein, in use, when the movable cover is lifted in the vertical direction with respect to the fixed cover into a position above the fixed cover, an expanded space (S') as the nacelle inner space is formed below the lifted movable cover such that the expanded space (S') is covered with the movable cover on the upper side, and wherein the movable cover is configured such that, when, in use, the movable cover is lifted in the vertical direction with respect to the fixed cover into the position above the fixed cover, the temporary lifting and lowering device is disposed in the expanded space (S') formed by the moveable cover in the vertical direction with respect to the fixed cover in use of the temporary lifting and lowering device.
Panel holder for at least one first panel, in particular for at least one first intermediate panel of a household appliance, having a locking unit with at least one first holding means (12a, 12b), by way of which with an assembly movement of the panel substantially in the direction of its perpendicular a locking connection can be established, wherein the panel holder comprises at least one spring element, by way of which in the assembled state substantially parallel to its surface extent the panel can be loaded with a spring force, characterised by at least one actuation element for deflecting the spring element, wherein the first holding means (12a, 12b) of the locking unit can be guided out of its locking position using the actuation element; and at least one fastening means (16, 17, 19, 20) for fastening to a support unit, which has at least one oblique surface (21a, 21b, 22a, 22b, 23a, 23b, 24a, 24b) for self-centring purposes when the spring element is deflected.
A block copolymer comprising a first block represented by Formula 6 and a second block represented by Formula 8: wherein R 1 and R 2 each independently are hydrogen or an alkyl group having 1 to 4 carbon atoms; X is a carbonyl group, -C(=O)-X 1 - or -X 1 -C(=O)-, wherein X 1 is an oxygen atom or a sulfur atom; T is an arylene group having 6 to 13 carbon atoms; Q is a single bond or a carbonyl group; and Y is a linear hydrocarbon chain having 8 to 20 chain-forming atoms, wherein X 2 is a single bond, an oxygen atom, a sulfur atom, -C(=O)-X 1 - or - X 1 -C(=O)-, wherein X 1 is a single bond, an oxygen atom or a sulfur atom; and W is an aryl group that has 6 to 12 carbon atoms and that is substituted with 2 or more halogen atoms.
A process for preparing a ceramic granulate, comprising at least: - a step of dry grinding ceramic raw materials to obtain a ceramic powder, - a step of wetting said ceramic powder with at least one liquid substance to obtain an agglomerated product, - a step of compacting said agglomerated product by applying a compaction pressure to obtain at least one compacted element, - a step of crushing said compacted element to obtain the ceramic granulate. - a step of sieving with a sieve the ceramic granulate to separate the coarse particles therefrom, - a step of inertial separation of the ceramic granulate to separate the fine particles therefrom. - a step of dry grinding ceramic raw materials to obtain a ceramic powder, - a step of wetting said ceramic powder with at least one liquid substance to obtain an agglomerated product, - a step of compacting said agglomerated product by applying a compaction pressure to obtain at least one compacted element, - a step of crushing said compacted element to obtain the ceramic granulate. - a step of sieving with a sieve the ceramic granulate to separate the coarse particles therefrom, - a step of inertial separation of the ceramic granulate to separate the fine particles therefrom.
A medical device comprising: a shaft (102; 302a; 302b; 402; 802) including a working channel (230; 330a; 330b; 430) extending from a proximal end of the shaft to a distal end of the shaft (102; 302a; 302b; 402; 802); an ultrasound sensor (150; 350a; 350b; 450; 850) disposed radially outward of a distal portion of the working channel (230; 330a; 330b; 430) such that the ultrasound sensor (150; 350a; 350b; 450; 850) at least partially surrounds the working channel (230; 330a; 330b; 430); an instrument (710; 720; 820) translatable from the proximal end of the shaft (102; 302a; 302b; 402; 802) to the distal end of the shaft (102; 302a; 302b; 402; 802), wherein the working channel (230; 330a; 330b; 430) receives the instrument (710; 720; 820) and maintains an orientation of the instrument (710; 720; 820) with respect to the shaft (102; 302a; 302b; 402; 802) so that a distal end of the instrument (710; 720; 820) has a unique radial location upon exiting the distal end of the shaft (102; 302a; 302b; 402; 802); and an area (211; 411; 811) having an echogenic signature distinct from a remainder of the shaft (102; 302a; 302b; 402; 802), the area (211; 411; 811) being provided at a distal portion of the shaft (102; 302a; 302b; 402; 802). a shaft (102; 302a; 302b; 402; 802) including a working channel (230; 330a; 330b; 430) extending from a proximal end of the shaft to a distal end of the shaft (102; 302a; 302b; 402; 802); an ultrasound sensor (150; 350a; 350b; 450; 850) disposed radially outward of a distal portion of the working channel (230; 330a; 330b; 430) such that the ultrasound sensor (150; 350a; 350b; 450; 850) at least partially surrounds the working channel (230; 330a; 330b; 430); an instrument (710; 720; 820) translatable from the proximal end of the shaft (102; 302a; 302b; 402; 802) to the distal end of the shaft (102; 302a; 302b; 402; 802), wherein the working channel (230; 330a; 330b; 430) receives the instrument (710; 720; 820) and maintains an orientation of the instrument (710; 720; 820) with respect to the shaft (102; 302a; 302b; 402; 802) so that a distal end of the instrument (710; 720; 820) has a unique radial location upon exiting the distal end of the shaft (102; 302a; 302b; 402; 802); and an area (211; 411; 811) having an echogenic signature distinct from a remainder of the shaft (102; 302a; 302b; 402; 802), the area (211; 411; 811) being provided at a distal portion of the shaft (102; 302a; 302b; 402; 802).