mhurhangee/ep-ind-claims huggingface dataset:
A compound of formula I wherein R 1 is hydrogen, C 1 -C 7 alkyl, C 1 -C 7 alkyl substituted by halogen, halogen, C 1 -C 7 alkoxy or C 1 -C 7 alkoxy substituted by halogen; R 1 may be the same or different, if n = 2 or 3; n is 1, 2 or 3; m is 1, 2 or 3; Ar is a five or six membered heteroaryl group, selected from wherein R 2 is hydrogen, C 1 -C 7 alkyl, C 1 -C 7 alkyl substituted by halogen, halogen or C 1 -C 7 alkoxy; R 3 is hydrogen or halogen; -() m - is ―(CH 2) m - or pharmaceutically active acid addition salts thereof. R 1 is hydrogen, C 1 -C 7 alkyl, C 1 -C 7 alkyl substituted by halogen, halogen, C 1 -C 7 alkoxy or C 1 -C 7 alkoxy substituted by halogen; R 1 may be the same or different, if n = 2 or 3; n is 1, 2 or 3; m is 1, 2 or 3; Ar is a five or six membered heteroaryl group, selected from wherein R 2 is hydrogen, C 1 -C 7 alkyl, C 1 -C 7 alkyl substituted by halogen, halogen or C 1 -C 7 alkoxy; R 3 is hydrogen or halogen; R 2 is hydrogen, C 1 -C 7 alkyl, C 1 -C 7 alkyl substituted by halogen, halogen or C 1 -C 7 alkoxy; R 3 is hydrogen or halogen; -() m - is ―(CH 2) m -
A method of increasing the likelihood an electronic message will be opened by a targeted recipient comprising: determining a time zone corresponding to an address of a targeted recipient; accessing an opening history for a set of electronic mail recipients within a domain including the targeted recipient; determining common times during which unsolicited email is sent; determining (9, 14) from the time zone, the opening history, and the common times during which unsolicited email is sent, at least one of a time and a day for sending an electronic message to the target recipient to increase likelihood that the electronic message will be opened; and improving the accuracy of a subsequent determination of at least one of a time and a day for sending an electronic message to a recipient by embedding a tracking code in the electronic message, the tracking code being configured to record the exact time the electronic message was opened in the opening history. determining a time zone corresponding to an address of a targeted recipient; accessing an opening history for a set of electronic mail recipients within a domain including the targeted recipient; determining common times during which unsolicited email is sent; determining (9, 14) from the time zone, the opening history, and the common times during which unsolicited email is sent, at least one of a time and a day for sending an electronic message to the target recipient to increase likelihood that the electronic message will be opened; and improving the accuracy of a subsequent determination of at least one of a time and a day for sending an electronic message to a recipient by embedding a tracking code in the electronic message, the tracking code being configured to record the exact time the electronic message was opened in the opening history.
A container with fold-out opening, of the type used for storing and dispensing granulated or liquid products, which comprises a vessel with a parallelepiped rectangular configuration, said vessel resulting from the suitable bending and folding of a laminar body, the laminar body having transversal bending lines that define four rectangular walls (21, 22, 23, 24) arranged adjacent to each other, which have an upper flap that is common to them and that defines the upper base of the vessel, and have another, lower flap common to them that is equipped with bending lines, which defines the lower support base of the vessel; wherein the upper flap has two folding lines that continue two transverse bending lines defining one of the four walls of the laminar body that is in a central position; said folding lines defining three rectangular portions (6, 7, 8) of the upper flap and are prolongations of each one of three walls (22, 23, 24) of the laminar body respectively; the central portion of the three rectangular portions (6, 7, 8) having the same axis of symmetry as the central wall and being a continuation thereof; and the other first and second lateral portions (6, 8) of the upper flap being symmetrical with respect to the axis of symmetry and are a continuation of two walls (22, 24) of the laminar body; each of the first and second lateral portions (6, 8) being provided with a respective first and second addition (61,81) on the edges opposite the contact thereof with the walls (22, 24); the first addition having a transversal tear line that divides the first addition into two dividing parts (611, 612), one being further from the axis of symmetry than the other, and characterised in that the second addition has a free edge that is symmetrical to the tear line with respect to the axis of symmetry and that the second portion has a slot close to the central portion, and the first addition having a tab in the dividing part thereof closest to the central portion and which can be engaged and inserted into the slot.
A double closed-loop regulated device for regulating a flow of oxygen for automated oxygen therapy, the device comprising an oxygen flow path (5a-c) for passing a flow of oxygen from a source of oxygen via the device for providing a controlled flow of oxygen, the device comprising a valve and a flowmeter arranged consecutively on the oxygen flow path (5a-c), and a controller configured for controlling a provided flow of oxygen through the valve by adjusting the valve in response to feedback (16,31) from the flowmeter and a sensor for measuring sets of physiological data comprising patient SpO 2 and pulse rate, the sensor configured for being operatively connected to the controller; the controller further configured for: - providing a first flow of oxygen for a first set time t 1 and, in response to a first set of physiological data comprising patient SpO 2 and pulse rate received from the sensor, establishing a second set time t 2; - providing a variable second flow of oxygen for the second set time t 2 while receiving a second set of physiological data comprising patient SpO 2 and pulse rate from the sensor; - establishing a third set time t 3 in response to the second set of physiological data received; and - providing a third flow of oxygen for the third set time t 3 without receiving feedback from the sensor. - providing a first flow of oxygen for a first set time t 1 and, in response to a first set of physiological data comprising patient SpO 2 and pulse rate received from the sensor, establishing a second set time t 2; - providing a variable second flow of oxygen for the second set time t 2 while receiving a second set of physiological data comprising patient SpO 2 and pulse rate from the sensor; - establishing a third set time t 3 in response to the second set of physiological data received; and - providing a third flow of oxygen for the third set time t 3 without receiving feedback from the sensor.
A process for continuous hydrogenation of dinitrotoluene to tolylenediamine in a liquid reaction mixture comprising dinitrotoluene in the presence of a supported catalyst which comprises as the active component a mixture of nickel and platinum in an atom ratio of nickel to platinum of from 30:70 to 70:30 and optionally one or more additional metals, wherein the hydrogenation is performed in the presence of at least one salt selected from the group consisting of the salts of the alkali metals, alkaline earth metals and of the rare earth metals.
A method for detecting particles in a fluid flow, said method comprising the steps of: providing said fluid flow having said particles; exposing said fluid flow to a beam of electromagnetic radiation from a laser, thereby generating scattered or emitted electromagnetic radiation; collecting and directing said scattered or emitted electromagnetic radiation from a viewing region onto a plurality of detector elements; wherein each detector element is positioned to receive said scattered or emitted electromagnetic radiation from a different portion of said viewing region; detecting said electromagnetic radiation directed onto said plurality of detector elements, wherein each of said detector elements generates independent output signals; and comparing output signals from at least two different detector elements to discriminate output signals corresponding to a particle detection event from output signals corresponding to a laser noise event; characterised in that the method comprises the steps of: analyzing output signals corresponding to said detection event, and identifying said laser noise event, wherein said laser noise event is identified when the output signals of each of at least two non-adjacent detector elements is independently equal to or greater than a threshold value; thereby detecting said particles in said fluid flow. providing said fluid flow having said particles; exposing said fluid flow to a beam of electromagnetic radiation from a laser, thereby generating scattered or emitted electromagnetic radiation; collecting and directing said scattered or emitted electromagnetic radiation from a viewing region onto a plurality of detector elements; wherein each detector element is positioned to receive said scattered or emitted electromagnetic radiation from a different portion of said viewing region; detecting said electromagnetic radiation directed onto said plurality of detector elements, wherein each of said detector elements generates independent output signals; and comparing output signals from at least two different detector elements to discriminate output signals corresponding to a particle detection event from output signals corresponding to a laser noise event; characterised in that the method comprises the steps of: analyzing output signals corresponding to said detection event, and identifying said laser noise event, wherein said laser noise event is identified when the output signals of each of at least two non-adjacent detector elements is independently equal to or greater than a threshold value; thereby detecting said particles in said fluid flow. analyzing output signals corresponding to said detection event, and identifying said laser noise event, wherein said laser noise event is identified when the output signals of each of at least two non-adjacent detector elements is independently equal to or greater than a threshold value; thereby detecting said particles in said fluid flow.
A catheter calibration system, comprising: a calibration chamber, configured to generate a calibration magnetic field that oscillates at a first frequency, the calibration chamber comprising a cavity for inserting a distal end of a catheter having one or more magnetic-field sensors; a receiver, which is configured to be connected to the catheter that is inserted in the cavity of the calibration chamber, to receive from the catheter one or more signals, which are generated by the one or more magnetic-field sensors in response to the calibration magnetic field, and to convert the one or more signals into one or more respective intermediate frequency signals having a second frequency that is lower than the first frequency by multiplying the one or more signals by a Local Oscillator signal; and a processor, which is configured to receive the one or more IF signals from the receiver and to calculate catheter navigation calibration data from the one or more IF signals. a calibration chamber, configured to generate a calibration magnetic field that oscillates at a first frequency, the calibration chamber comprising a cavity for inserting a distal end of a catheter having one or more magnetic-field sensors; a receiver, which is configured to be connected to the catheter that is inserted in the cavity of the calibration chamber, to receive from the catheter one or more signals, which are generated by the one or more magnetic-field sensors in response to the calibration magnetic field, and to convert the one or more signals into one or more respective intermediate frequency signals having a second frequency that is lower than the first frequency by multiplying the one or more signals by a Local Oscillator signal; and a processor, which is configured to receive the one or more IF signals from the receiver and to calculate catheter navigation calibration data from the one or more IF signals.
A T-cell receptor alpha or beta chain fusion protein for expression on the surface of a T cell, wherein said T-cell receptor alpha or beta chain fusion protein is able to bind to its specific peptide-MHC complex for depletion of said T cell expressing said fusion protein using an epitope-tag specific antibody, comprising: a) the epitope-providing amino acid sequence (epitope-tag), and b) the amino acid sequence of an alpha or beta chain of a TCR, wherein said epitope-tag is an epitope-tag added to the N-terminus of said alpha and/or beta chain. a) the epitope-providing amino acid sequence (epitope-tag), and b) the amino acid sequence of an alpha or beta chain of a TCR,
An apparatus (30,60) for forced ventilation of patients which comprises: - at least one ventilation device (40,70) selected from the arrangement consisting of a venturi-effect oxygen-air mixer and an exhalation valve; characterized in that the apparatus (30,60) comprises: - a silencer body (50,80) delimiting an internal cavity (51,81) and provided with at least one access opening (52,82) that puts the outside of the silencer body (50,80) in communication with the internal cavity (51,81) thereof and at least one outlet opening (53,83) that puts the internal cavity (51,81) in communication with the outside of the silencer body (50,80); wherein the access opening (52,82) and the outlet opening (53,83) are separate from each other; and in that the ventilation device (40,70) is at least partially arranged inside the internal cavity (51,81) of the silencer body (50,80) and fixed to the silencer body (50,80). - at least one ventilation device (40,70) selected from the arrangement consisting of a venturi-effect oxygen-air mixer and an exhalation valve; - a silencer body (50,80) delimiting an internal cavity (51,81) and provided with at least one access opening (52,82) that puts the outside of the silencer body (50,80) in communication with the internal cavity (51,81) thereof and at least one outlet opening (53,83) that puts the internal cavity (51,81) in communication with the outside of the silencer body (50,80); wherein the access opening (52,82) and the outlet opening (53,83) are separate from each other;
Compression garment comprising a pants section with a rear side, wherein the rear side comprises an insert, a first side section and a second side section, the first side section being connected to a first side of the insert, the second side section being connected to a second side of the insert, wherein the insert is adapted to extend over at least part of both buttocks of a wearer, wherein the insert consists of a seamless knitted fabric; and wherein the insert is located between the first side section and the second side section and a waistband section; or the insert is located between the first side section and the second side section and forms part of the upper end of the garment. the first side section being connected to a first side of the insert, the second side section being connected to a second side of the insert, wherein the insert is adapted to extend over at least part of both buttocks of a wearer, wherein the insert consists of a seamless knitted fabric; and wherein the insert is located between the first side section and the second side section and a waistband section; or the insert is located between the first side section and the second side section and forms part of the upper end of the garment.
Process for preparing cyclic amides from the corresponding ketoximes by heating the ketoxime in the presence of cyanuric chloride, characterized in that the ketoxime is cyclic ketoxime having a ring size of 6-12, the reaction is performed in the presence of an amount of cyanuric chloride based on the amide of 1.5 - 13 mol%, the reaction is performed in a nonpolar organic solvent having a logP value (octanol-water) of 2 - 14,and wherein the solvents is selected from the group consisting of cyclododecane, cyclodecane, cyclooctane, cycloheptane, cyclohexane, cyclopentane, n-nonane, n-octane, n-heptane, n-hexane, n-pentane, isooctane, hydrocumene, and mixtures thereof.
An electric power tool, comprising: a control system coupled to an electric power supply and an electric motor, the control system configured to cause an electric current to be supplied to the electric motor to drive a load, wherein: the control system includes a continuous power mode wherein the electric current is supplied up to a first level and a boost power mode wherein the electric current is supplied up to a second level, the second level being greater than the first level, and the control system is to switch from the continuous power mode to the boost power mode when the control system senses an increase in the load past a predetermined threshold, and is to switch from the boost power mode to the continuous power mode when the control system senses a decrease in the load; the control system is characterised in that it further has a cutback power mode wherein the electric current is supplied up to a third level that is less than the first level, and is to switch to the cutback power mode if the load on the electric motor does not decrease below the predetermined threshold before a predetermined time elapses. a control system coupled to an electric power supply and an electric motor, the control system configured to cause an electric current to be supplied to the electric motor to drive a load, wherein: the control system includes a continuous power mode wherein the electric current is supplied up to a first level and a boost power mode wherein the electric current is supplied up to a second level, the second level being greater than the first level, and the control system is to switch from the continuous power mode to the boost power mode when the control system senses an increase in the load past a predetermined threshold, and is to switch from the boost power mode to the continuous power mode when the control system senses a decrease in the load; the control system includes a continuous power mode wherein the electric current is supplied up to a first level and a boost power mode wherein the electric current is supplied up to a second level, the second level being greater than the first level, and the control system is to switch from the continuous power mode to the boost power mode when the control system senses an increase in the load past a predetermined threshold, and is to switch from the boost power mode to the continuous power mode when the control system senses a decrease in the load; the control system is characterised in that it further has a cutback power mode wherein the electric current is supplied up to a third level that is less than the first level, and is to switch to the cutback power mode if the load on the electric motor does not decrease below the predetermined threshold before a predetermined time elapses.
Spring brake cylinder, having a piston which is guided in a sealed manner in the housing of the spring brake cylinder, is configured in a hat-shaped manner with a cylindrical centre part and a radially protruding flange, and in which a prestressed compression spring is arranged which is supported on one side on a transverse wall of the piston and on the other side on a transverse wall of the housing of the spring brake cylinder, an annular space which can be loaded with compressed air being formed between the cylindrical centre part and the housing of the spring brake cylinder, and in which the transverse wall of the piston can bear against a service brake piston of an air brake cylinder which is combined with the spring brake cylinder to form a structural unit, in order to actuate the said air brake cylinder in the braking direction by means of the compression spring in the case of a pressure drop in the annular space, characterized in that the cylindrical centre part of the piston is guided with its cylindrical outer side in an opening of a dividing wall between the housing of the spring brake cylinder and a housing of the air brake cylinder and with its cylindrical inner side on a cylindrical outer side of a cylindrical guide element which protrudes from the transverse wall of the housing of the spring brake cylinder in the direction of the transverse wall of the piston.
A medical device comprising:- a balloon (3, 51, 61, 71) for location in a blood vessel, the balloon having at each end an end part; the balloon being inflatable between a collapsed configuration and an expanded configuration; wherein in the expanded configuration at least part of the longitudinal axis of the balloon is curved in three-dimensional space; characterised in that: in the expanded configuration at least part of the balloon is substantially helically shaped; and wherein a longitudinal axis of each end part of the balloon has a helical angle that varies along the length of the end part and which increases in a direction away from the end of the balloon. in the expanded configuration at least part of the balloon is substantially helically shaped; and wherein a longitudinal axis of each end part of the balloon has a helical angle that varies along the length of the end part and which increases in a direction away from the end of the balloon.
A method of assisting user-configuration of hardware for a mobile autonomous cleaning robot, the method comprising: detecting a flooring type of a portion of an environment; characterized in that the method further comprises: detecting a size of the portion of the environment; determining a total size of the environment; generating a roller type recommendation based at least in part on the flooring type, the size of the portion of the environment, and the total size of the environment; and transmitting the roller type recommendation to a user interface device. detecting a flooring type of a portion of an environment; characterized in that the method further comprises: detecting a size of the portion of the environment; determining a total size of the environment; generating a roller type recommendation based at least in part on the flooring type, the size of the portion of the environment, and the total size of the environment; and transmitting the roller type recommendation to a user interface device. detecting a size of the portion of the environment; determining a total size of the environment; generating a roller type recommendation based at least in part on the flooring type, the size of the portion of the environment, and the total size of the environment; and transmitting the roller type recommendation to a user interface device.
Method for detecting a maintenance situation in a two-wheeled vehicle driven by means of an engine, in particular a motorcycle, wherein • a position variable (S 1) which represents the orientation of the two-wheeled vehicle with respect to the underlying surface or the carriageway is acquired, and • the power of the engine is controlled as a function of the position variable (S 1), wherein a maintenance situation is detected as a function of the position variable (S 1) and the power which is output by the engine is reduced at least temporarily during the maintenance situation. • a position variable (S 1) which represents the orientation of the two-wheeled vehicle with respect to the underlying surface or the carriageway is acquired, and • the power of the engine is controlled as a function of the position variable (S 1),