An endoscope operation section comprising: an angle operation member (11, 12) for bending a bending portion provided in an insertion portion of an endoscope, the angle operation member (11, 12) being provided in an operation section body of the endoscope operation section provided at a proximal end of the insertion portion; a first switch button for performing first operation of the endoscope, the first switch button being provided in a first surface of the operation section body; and a second switch button for performing second operation of the endoscope, the second switch button being provided side by side with the first switch button in the first surface and positioned on a side distant from the angle operation member (11, 12) relative to the first switch button, wherein a universal cord extends from a third surface that is adjacent to the first surface of the operation section body and faces a second surface adjacent to the first surface, wherein the first switch button and the second switch button are formed at positions of the first surface where the first switch button and the second switch button are suitable of being operated by a thumb when the operation section body is grasped by one hand in such a manner that a base of the universal cord is held between the thumb and an index finger, and wherein the angle operation member is provided in the second surface, characterized in that an outer circumferential side of the second switch button is covered by a sheathing member of the operation section body, and a projection portion of the sheathing member is formed at a site of the sheathing member facing the first switch button, on an outer circumference of the second switch button, the projection portion projecting toward a side away from the first surface relative to another site of the sheathing member on the outer circumference of the second switch button. an angle operation member (11, 12) for bending a bending portion provided in an insertion portion of an endoscope, the angle operation member (11, 12) being provided in an operation section body of the endoscope operation section provided at a proximal end of the insertion portion; a first switch button for performing first operation of the endoscope, the first switch button being provided in a first surface of the operation section body; and a second switch button for performing second operation of the endoscope, the second switch button being provided side by side with the first switch button in the first surface and positioned on a side distant from the angle operation member (11, 12) relative to the first switch button, wherein a universal cord extends from a third surface that is adjacent to the first surface of the operation section body and faces a second surface adjacent to the first surface, wherein the first switch button and the second switch button are formed at positions of the first surface where the first switch button and the second switch button are suitable of being operated by a thumb when the operation section body is grasped by one hand in such a manner that a base of the universal cord is held between the thumb and an index finger, and wherein the angle operation member is provided in the second surface, characterized in that an outer circumferential side of the second switch button is covered by a sheathing member of the operation section body, and a projection portion of the sheathing member is formed at a site of the sheathing member facing the first switch button, on an outer circumference of the second switch button, the projection portion projecting toward a side away from the first surface relative to another site of the sheathing member on the outer circumference of the second switch button.