A computer-implemented method for remotely managing Self-Encrypting Disks referred to as "SEDs", via client/server topology, comprising the use of one or more remote SEDs, mounted on a computer including a CPU, a memory, a motherboard and a bus, and remotely connected through a telecommunications network to a sole server and having respective unencrypted partitions thereon which are freely accessible by the sole server and respective secure partitions, wherein the following steps are performed: A. loading and running respective disk unlocking client programs by said one or more remote SEDs from said respective freely accessible partitions, B. requesting (125,143), by said respective disk unlocking client programs, one or more passwords to said sole server, respectively; C. sending (136, 144, 126), by the sole server, said one or more passwords to said one or more remote SEDs, respectively; and D. unlocking, by said respective disk unlocking client programs, the respective secure partitions, if said one or more passwords match one or more predetermined passwords, respectively; and wherein: - the one or more remote SED disks support Opal Storage Specification; - the respective disk unlocking client programs run on the one or more remote SED disks and are OPAL clients; - the sole server is a sole OPAL server; - in step B, the respective OPAL clients compute and send to the sole server respective footprints on the basis of predetermined information, the respective footprints being computed as respective hashes of respective alphanumeric strings obtained on the basis of respective CPU serial numbers of the respective boards on which said one or more disks are mounted, as well as the respective serial disk numbers; - in step C, the sole OPAL server checks for the presence of said respective footprints in a list of authorized footprints, before sending (136,144) said one or more passwords, respectively, to the OPAL clients; - step D is performed by restarting said one or more remote SEDs, wherein, at each restart of said one or more remote SEDs, the respective, freely accessible partitions and the respective secure partitions become alternately freely accessible; - a Tiny Core operating system is installed on an unencrypted partition of the one or more remote SEDs freely accessible by the sole OPAL server. A. loading and running respective disk unlocking client programs by said one or more remote SEDs from said respective freely accessible partitions, B. requesting (125,143), by said respective disk unlocking client programs, one or more passwords to said sole server, respectively; C. sending (136, 144, 126), by the sole server, said one or more passwords to said one or more remote SEDs, respectively; and D. unlocking, by said respective disk unlocking client programs, the respective secure partitions, if said one or more passwords match one or more predetermined passwords, respectively; - the one or more remote SED disks support Opal Storage Specification; - the respective disk unlocking client programs run on the one or more remote SED disks and are OPAL clients; - the sole server is a sole OPAL server; - in step B, the respective OPAL clients compute and send to the sole server respective footprints on the basis of predetermined information, the respective footprints being computed as respective hashes of respective alphanumeric strings obtained on the basis of respective CPU serial numbers of the respective boards on which said one or more disks are mounted, as well as the respective serial disk numbers; - in step C, the sole OPAL server checks for the presence of said respective footprints in a list of authorized footprints, before sending (136,144) said one or more passwords, respectively, to the OPAL clients; - step D is performed by restarting said one or more remote SEDs, wherein, at each restart of said one or more remote SEDs, the respective, freely accessible partitions and the respective secure partitions become alternately freely accessible; - a Tiny Core operating system is installed on an unencrypted partition of the one or more remote SEDs freely accessible by the sole OPAL server.