mhurhangee/ep-ind-claims huggingface dataset:
A composition comprising a compound of Formula I for use in a method of treating age-related macular degeneration in a human patient in need of such treatment, which comprises administering a therapeutically effective amount of the composition comprising a compound of Formula I, its individual enantiomers, its individual diastereoisomers, its hydrates, its solvates, its crystal forms, its individual tautomers or a pharmaceutically acceptable salt thereof, wherein R 1 is H or C 1-3 alkyl; R 2 is H or C 1-3 alkyl; R 3 is H, C 1-10 alkyl, heterocycle or aryl; and R is C 1-10 alkyl, heterocycle or aryl, wherein "alkyl" means a saturated monovalent alkane moiety having straight or branched alkane moieties or combinations thereof, which may optionally be substituted by amino groups, aryl groups, halogens, and one methylene (-CH 2 -) can be replaced by carbonyl, -NH-, carboxyl, amide, sulfur or by oxygen, and "heterocycle" means an aromatic or non-aromatic 5 to 10 membered monocyclic or bicyclic ring containing at least one heteroatom selected from O or N or S or combinations thereof, interrupting the carbocyclic ring structure, which may optionally be substituted by C 1-6 alkyl, amino, halogen, -O(C 1-6 alkyl), -OC (C 1-6 alkyl), - C O(C 1-6 alkyl), -NHC (C 1-6 alkyl), -C NH(C 1-6 alkyl), -S(C 1-6 alkyl) groups, and "aryl" means an organic moiety derived from an aromatic hydrocarbon consisting of a monocyclic or bicyclic ring containing 6-10 carbon atoms by removal of one hydrogen atom, such as phenyl or naphthyl, which may optionally be substituted by, but not limited to, C 1-6 alkyl, amino, halogen, -O(C 1-6 alkyl), -OC (C 1-6 alkyl), -C O(C 1-6 alkyl), -NHC (C 1-6 alkyl), -C NH(C 1-6 alkyl), and -S(C 1-6 alkyl) groups. R 1 is H or C 1-3 alkyl; R 2 is H or C 1-3 alkyl; R 3 is H, C 1-10 alkyl, heterocycle or aryl; and R is C 1-10 alkyl, heterocycle or aryl, wherein "alkyl" means a saturated monovalent alkane moiety having straight or branched alkane moieties or combinations thereof, which may optionally be substituted by amino groups, aryl groups, halogens, and one methylene (-CH 2 -) can be replaced by carbonyl, -NH-, carboxyl, amide, sulfur or by oxygen, and "heterocycle" means an aromatic or non-aromatic 5 to 10 membered monocyclic or bicyclic ring containing at least one heteroatom selected from O or N or S or combinations thereof, interrupting the carbocyclic ring structure, which may optionally be substituted by C 1-6 alkyl, amino, halogen, -O(C 1-6 alkyl), -OC (C 1-6 alkyl), - C O(C 1-6 alkyl), -NHC (C 1-6 alkyl), -C NH(C 1-6 alkyl), -S(C 1-6 alkyl) groups, and "aryl" means an organic moiety derived from an aromatic hydrocarbon consisting of a monocyclic or bicyclic ring containing 6-10 carbon atoms by removal of one hydrogen atom, such as phenyl or naphthyl, which may optionally be substituted by, but not limited to, C 1-6 alkyl, amino, halogen, -O(C 1-6 alkyl), -OC (C 1-6 alkyl), -C O(C 1-6 alkyl), -NHC (C 1-6 alkyl), -C NH(C 1-6 alkyl), and -S(C 1-6 alkyl) groups.
A refrigerant composition consisting of: four components, wherein a first component is nitrogen in the range of 5 mol. % to 35 mol. %, a second component is methane in the range of 20 mol. % to 40 mol. %, a third component is ethane or ethylene in the range of 10 mol. % to 45 mol. %, and a fourth component is one of 1- butene, n-butane, isobutane, n-pentane or isopentane in the range of 10 mol. % to 35 mol. % or propane or propylene in the range of 10 mol. % to 45 mol. % provided that the sum of the concentrations of the above-mentioned components does not exceed 100 mol%; five components, wherein a first component is nitrogen in the range of 5 mol. % to 35 mol. %, a second component is methane in the range of 20 mol. % to 40 mol. %, a third component is ethane or ethylene in the range of 10 mol. % to 45 mol. %, a fourth component is one of 1- butene, n-butane, isobutane, n-pentane or isopentane in the range of 10 mol. % to 35 mol. % or propane or propylene in the range of 10 mol. % to 45 mol. %, and a fifth component is one of n-butane, isobutane, propane, propylene, n-pentane and isopentane, wherein said the fifth component is different from said fourth component. provided that the sum of the concentrations of the above-mentioned components does not exceed 100 mol%. four components, wherein a first component is nitrogen in the range of 5 mol. % to 35 mol. %, a second component is methane in the range of 20 mol. % to 40 mol. %, a third component is ethane or ethylene in the range of 10 mol. % to 45 mol. %, and a fourth component is one of 1- butene, n-butane, isobutane, n-pentane or isopentane in the range of 10 mol. % to 35 mol. % or propane or propylene in the range of 10 mol. % to 45 mol. % provided that the sum of the concentrations of the above-mentioned components does not exceed 100 mol%; five components, wherein a first component is nitrogen in the range of 5 mol. % to 35 mol. %, a second component is methane in the range of 20 mol. % to 40 mol. %, a third component is ethane or ethylene in the range of 10 mol. % to 45 mol. %, a fourth component is one of 1- butene, n-butane, isobutane, n-pentane or isopentane in the range of 10 mol. % to 35 mol. % or propane or propylene in the range of 10 mol. % to 45 mol. %, and a fifth component is one of n-butane, isobutane, propane, propylene, n-pentane and isopentane, wherein said the fifth component is different from said fourth component. provided that the sum of the concentrations of the above-mentioned components does not exceed 100 mol%.
Method for separating off individual pieces from a metal strip, which comes from a rolling installation, by drum shears, as well as discharge means downstream thereof for the separated metal strip pieces, wherein a diverter pivotable into or out of the plane of the metal strip is provided at the outlet of the metal strip from the shears, wherein depending on the kind of metal strip pieces to be separated the pivot angle of the diverter is alignable with channels, which serve for conducting away, for pieces of scrap, chopped pieces (16, 18) or croppings, or serves for conducting through the head piece of the metal strip, characterised in that through the pivotable diverter behind the drum shears a) in the case of cropping at the material head the opening in the scrap channel (6, 11) is reduced and the new strip head is conducted via the scrap channel (6, 11) for transiting operation, b) in the case of chopping, the opening via the scrap channel (6, 11) is enlarged and the chopped piece is conducted downwardly into the scrap channel, wherein on initiation of a chopping process, with transiting material, after the first cut the speed of the entering material is reduced or the speed of the exiting material is increased and thus a gap is created, c) after the end of the chopping process, through reducing the opening of the scrap channel (6, 11) the new strip head is further conducted via the scrap channel for transiting operation. a) in the case of cropping at the material head the opening in the scrap channel (6, 11) is reduced and the new strip head is conducted via the scrap channel (6, 11) for transiting operation, b) in the case of chopping, the opening via the scrap channel (6, 11) is enlarged and the chopped piece is conducted downwardly into the scrap channel, wherein on initiation of a chopping process, with transiting material, after the first cut the speed of the entering material is reduced or the speed of the exiting material is increased and thus a gap is created, c) after the end of the chopping process, through reducing the opening of the scrap channel (6, 11) the new strip head is further conducted via the scrap channel for transiting operation.
A multicast bearer management method, comprising: in a process of receiving service data of a single cell-multimedia broadcast multicast service traffic channel, SC-MTCH, suspending a single cell-multimedia broadcast multicast service point to multipoint radio bearer, SC-MRB, corresponding to the SC-MTCH when there is a first type of data to be received; and when reception of the first type of data is completed, restoring or releasing the SC-MRB based on a temporary mobile group identity, TMGI, and/or a session identity corresponding to the SC-MRB; wherein the suspending an SC-MRB corresponding to the SC-MTCH comprises: reserving a radio link control, RLC, entity corresponding to the SC-MRB, and releasing a media access control, MAC, layer configuration and/or a physical layer configuration corresponding to the SC-MRB in a process of receiving service data of a single cell-multimedia broadcast multicast service traffic channel, SC-MTCH, suspending a single cell-multimedia broadcast multicast service point to multipoint radio bearer, SC-MRB, corresponding to the SC-MTCH when there is a first type of data to be received; and when reception of the first type of data is completed, restoring or releasing the SC-MRB based on a temporary mobile group identity, TMGI, and/or a session identity corresponding to the SC-MRB; wherein the suspending an SC-MRB corresponding to the SC-MTCH comprises: reserving a radio link control, RLC, entity corresponding to the SC-MRB, and releasing a media access control, MAC, layer configuration and/or a physical layer configuration corresponding to the SC-MRB
Force transmitting coupling for drivingly coupling winding devices of adjacent architectural coverings, the coupling including: a first coupling member; a second coupling member; characterized in that the coupling further includes mating engagement means (81, 83) on the first and second coupling members (31, 33) adapted to establish mating engagement between the first and second coupling member (31, 33) to transmit a drive force from one of the first and second coupling members (31, 33) to another of the first and second coupling members (31, 33); the second coupling member includes a hub; the engaging means on the second coupling member are positioned annularly on the second coupling member at a radial distance from the hub and are resiliently connected to the hub; and the resilient connection is formed integrally with the annular engaging means and the hub. a first coupling member; a second coupling member; characterized in that the coupling further includes mating engagement means (81, 83) on the first and second coupling members (31, 33) adapted to establish mating engagement between the first and second coupling member (31, 33) to transmit a drive force from one of the first and second coupling members (31, 33) to another of the first and second coupling members (31, 33); the second coupling member includes a hub; the engaging means on the second coupling member are positioned annularly on the second coupling member at a radial distance from the hub and are resiliently connected to the hub; and the resilient connection is formed integrally with the annular engaging means and the hub.
Trim component for cladding an interior space of a means of passenger transport, in particular a vehicle, the trim component comprising - a base body made of a plastic or polymer, - carbon fibers embedded into the plastic or polymer, and - at least one anode and at least one cathode welded onto the base body or embedded into the plastic or polymer, characterized in that - the content of carbon fibers embedded into the plastic or polymer is at least 10% (wt/wt) and - the carbon fibers are recycled carbon fibers. - a base body made of a plastic or polymer, - carbon fibers embedded into the plastic or polymer, and - at least one anode and at least one cathode welded onto the base body or embedded into the plastic or polymer, - the content of carbon fibers embedded into the plastic or polymer is at least 10% (wt/wt) and - the carbon fibers are recycled carbon fibers.
A system for electrical stimulation of a patient's cochlea, comprising a cochlear implant electrode arrangement (16, 18) comprising a plurality of stimulation channels; means for providing an audio signal; means for dividing the audio signal into a plurality of analysis channels, each containing a frequency domain signal representative of a distinct frequency portion of the audio signal; means (42, 54, 56) for determining a signal level value and a noise level value for each analysis channel by analyzing the respective frequency domain signal; means for applying noise reduction to the frequency domain signal according to noise reduction gain parameters to generate a noise reduced frequency domain signal; and means (14, 46, 48) for generating a stimulation signal for each of the stimulation channels according to the noise reduced frequency domain signal and supplying the stimulation signals to the electrode arrangement in order to stimulate the cochlea characterised by means for establishing an electrode-nerve-interface model of hearing stimulation via the cochlear implant electrode arrangement, the model describing, for each of the stimulation channels, the hearing perception impact of a stimulation signal applied to that stimulation channel on the other stimulation channels, wherein each stimulation channel is associated with at least one of the analysis channels, and means for determining the respective noise reduction gain parameter for at least some of the analysis channels as a function of the signal level value and the noise level value of the respective analysis channel, wherein the hearing perception impact of stimulation of stimulation channels other than the stimulation channel(s) associated with the respective analysis channel on the stimulation channel(s) associated with the respective analysis channel is taken into account via the electrode-nerve-interface model.
An aerosol generating device for use in an aerosol-generating system, the aerosol-generating device comprising: an outer housing, adapted to receive an aerosol-generating article comprising a first compartment comprising a volatile liquid, and a second compartment comprising a delivery enhancing compound; a power supply; at least one heater, configured to receive power from the power supply and arranged to heat the first compartment when an aerosol-generating article is received in the outer housing; at least one further heater configured to receive power from the power supply and arranged to heat the second compartment when the aerosol-generating article is received in the outer housing; an input, configured to receive a plurality of discrete inputs from a user, each discrete input corresponding to a respective discrete quantity of aerosolised volatile liquid required by the user, each discrete input from the user corresponding to a respective discrete duty cycle; and a controller, configured to control the amount of power supplied to the at least one heater by changing the duty cycle, such that the quantity of volatile liquid aerosolised is determined by the user input; wherein the controller is further configured to control the amount of power supplied to the at least one further heater, such that a quantity of delivery enhancing compound aerosolised is proportional to the quantity of volatile liquid aerosolised. an outer housing, adapted to receive an aerosol-generating article comprising a first compartment comprising a volatile liquid, and a second compartment comprising a delivery enhancing compound; a power supply; at least one heater, configured to receive power from the power supply and arranged to heat the first compartment when an aerosol-generating article is received in the outer housing; at least one further heater configured to receive power from the power supply and arranged to heat the second compartment when the aerosol-generating article is received in the outer housing; an input, configured to receive a plurality of discrete inputs from a user, each discrete input corresponding to a respective discrete quantity of aerosolised volatile liquid required by the user, each discrete input from the user corresponding to a respective discrete duty cycle; and a controller, configured to control the amount of power supplied to the at least one heater by changing the duty cycle, such that the quantity of volatile liquid aerosolised is determined by the user input; wherein the controller is further configured to control the amount of power supplied to the at least one further heater, such that a quantity of delivery enhancing compound aerosolised is proportional to the quantity of volatile liquid aerosolised.
A spindle for food processing, comprising: a shredding part for cutting the food into shred; and a compression part for compressing the shred, wherein the shredding part comprises a first body and a first helical member and the compression part comprises a second body connected with the first body and a second helical member, wherein the compression ratio of the shredding part to the compression part ranges from 2 to 10, wherein the compression ratio is defined by the ratio of a first volume V1 of the shredding part to a second volume V2 of the compression part, wherein the first volume V1 is defined by the following equation: V1 = pi ∗ D1/cos(alpha) ∗ A1, where D1 is an average diameter of the shredding part, alpha is a helix angle equal to arctan(P1/(pi ∗ D1)), where P1 refers to a pitch of the first helical member, and A1 is area defined by P1 ∗ H1, where H1 is a height of the first helical member, and wherein the second volume V2 is defined by the following equation: V2 = pi ∗ D2/cos(beta) ∗ A2, where D2 is an average diameter of the compression part, beta is a helix angle equal to arctan(P2/(pi ∗ D2)), where P2 refers to a pitch of the second helical member, and A2 is area defined by P2 ∗ H2, where H2 is a height of the second helical member. a shredding part for cutting the food into shred; and a compression part for compressing the shred, wherein the shredding part comprises a first body and a first helical member and the compression part comprises a second body connected with the first body and a second helical member, wherein the compression ratio of the shredding part to the compression part ranges from 2 to 10, wherein the compression ratio is defined by the ratio of a first volume V1 of the shredding part to a second volume V2 of the compression part, wherein the first volume V1 is defined by the following equation: V1 = pi ∗ D1/cos(alpha) ∗ A1, where D1 is an average diameter of the shredding part, alpha is a helix angle equal to arctan(P1/(pi ∗ D1)), where P1 refers to a pitch of the first helical member, and A1 is area defined by P1 ∗ H1, where H1 is a height of the first helical member, and wherein the second volume V2 is defined by the following equation: V2 = pi ∗ D2/cos(beta) ∗ A2, where D2 is an average diameter of the compression part, beta is a helix angle equal to arctan(P2/(pi ∗ D2)), where P2 refers to a pitch of the second helical member, and A2 is area defined by P2 ∗ H2, where H2 is a height of the second helical member.
A floor protector for a security access system, comprising a rigid floor assembly having front and rear edges (14, 15), the floor assembly comprising at least one floor plate and a base mounted underneath the floor plate, the base being at least partially spaced from the floor plate enabling cabling to pass between the two, and elastomeric entry and exit ramps (6, 7) supporting the front and rear edges of the floor assembly; wherein the base has elongate lips (14, 15) at its front and rear edges which locate within respective grooves in respective elastomeric ramps, spaced a distance above the lower surface of the ramp, so that the ramps themselves substantially support the base-plate, with the floor and the access control apparatus mounted upon it, spaced above the whole or a major part of the floor that it overlies; wherein each ramp comprises a narrow end and a wider end characterised in that each ramp further comprises a groove at the wider end extending inwardly into the ramp toward the narrow end and having a substantially "S" shaped cross section; and the lips (14, 15) at the front rear edges of the floor assembly have a corresponding "S" shaped cross section for fitting within the grooves in the ramp.
Oven for household or industrial application, comprising a muffle and at least one oven illumination for illuminating the interior of the muffle, the illumination comprises at least one light source and a lens, preferably made from glass, arranged downstream the at least one light source; characterised in that a cavity is provided with the lens body at least reducing heat conduction towards the at least one light source, and the oven comprises a heat sink for removing heat from the at least one oven illumination coupled thereto, wherein said heat sink is based on passive cooling comprising heat conduction via at least one part of a housing of the oven.
A cylinder lock with control key, including a stator, security pins, a rotor and a key, the rotor rotating in the stator under the action of the key, and, as additional means for authorizing the rotation of the rotor, an elastic leaf, the median plane of which contains the axis of the rotor, one end of which is attached in the rotor and the other end of which is free in radial movement, the free end of the elastic leaf being movable between an unstressed position, where it is completely housed in the rotor and where it allows the rotation of the rotor, and a stressed position, where it protrudes from the rotor and where it cooperates with a slot of the stator to prevent the rotation of the rotor, characterized in that the elastic leaf is made up of a first part parallel to the axis of the rotor and attached to the rotor, an intermediate part with a curved profile, extending toward the axis of the rotor, and an end part substantially perpendicular to the axis of the rotor and extending toward the outside of the rotor; and in that the key includes, on its blade, an indentation whose profile encompasses that of the intermediate part and the end part of the elastic leaf, such that, after introduction of the key, the elastic leaf, housed in said indentation, is not subject to any stress.
An article of footwear comprising an upper defining a throat configured to receive a foot; a sole structure coupled to the upper; a panel having a first side coupled to the upper for movement between an open position and a closed position, the panel exposing a portion of the throat in the open position and covering the portion of the throat in the closed position; and a strap having a first end and a second end opposite the first end, the first end and the second end disposed on a first side of the upper with a body portion of the strap disposed between the first end and the second end surrounding the upper; wherein the body portion of the strap includes a first portion and a second portion extending from the first portion, the first portion extending from the first end, the second portion extending from the second end and overlapping the first portion of the strap at an intersection. an upper defining a throat configured to receive a foot; a sole structure coupled to the upper; a panel having a first side coupled to the upper for movement between an open position and a closed position, the panel exposing a portion of the throat in the open position and covering the portion of the throat in the closed position; and a strap having a first end and a second end opposite the first end, the first end and the second end disposed on a first side of the upper with a body portion of the strap disposed between the first end and the second end surrounding the upper; wherein the body portion of the strap includes a first portion and a second portion extending from the first portion, the first portion extending from the first end, the second portion extending from the second end and overlapping the first portion of the strap at an intersection.