A heavy duty pneumatic tire comprising: a tread portion being provided with a circumferentially extending zigzag central main groove on a tire equator, a pair of circumferentially extending zigzag middle main grooves each located axially outwardly of the central main groove and a pair of circumferentially extending zigzag shoulder main grooves each located axially outwardly of each middle main groove to form a pair of central portions each between the central main groove and one of the middle main grooves, a pair of middle portions each between the middle main groove and the shoulder main groove on each side of the tire equator, and a pair of shoulder portions each between the shoulder main groove and a tread edge (Te) on each side of the tire equator, wherein each of the central portions, middle portions and shoulder portions has an axial width (WC, WM, WS) varying periodically while increasing and decreasing in a circumferential direction of the tire; each of the central portions being provided with a plurality of central lateral grooves to form a plurality of central blocks each having a hexagonal shaped top face, wherein each of the central lateral grooves communicates a zigzag peak (3h, 3k) of the central main groove with a zigzag peak of the middle main groove so that each central lateral groove is arranged at a location where the central portion has a minimum width; each of the middle portions being provided with a plurality of middle lateral grooves to form a plurality of middle blocks each having a hexagonal shaped top face, wherein each of the middle lateral grooves communicates a zigzag peak of the middle main groove with a zigzag peak of the shoulder main groove so that each middle lateral groove is arranged at a location where the middle portion has a minimum width; each of the shoulder portions being provided with a plurality of shoulder lateral grooves to form a plurality of shoulder blocks each having a polygonal top face, wherein each of the shoulder lateral grooves communicates a zigzag peak of the shoulder main groove with the tread edge (Te) so that each shoulder lateral groove is arranged at a location where the shoulder portion has a minimum width; each central block being provided with a central sipe extending in an axial direction of the tire; characterized in that a total that is the sum of each maximum axial width of the central portions, each maximum axial width of the middle portions, each maximum axial width of the shoulder portions, a maximum axial length of the central sipe provided on one of the central portions, and a maximum axial length of the central sipe provided on the other one of the central portions being in a range of from 1.05 to 1.31 times a tread width. a tread portion being provided with a circumferentially extending zigzag central main groove on a tire equator, a pair of circumferentially extending zigzag middle main grooves each located axially outwardly of the central main groove and a pair of circumferentially extending zigzag shoulder main grooves each located axially outwardly of each middle main groove to form a pair of central portions each between the central main groove and one of the middle main grooves, a pair of middle portions each between the middle main groove and the shoulder main groove on each side of the tire equator, and a pair of shoulder portions each between the shoulder main groove and a tread edge (Te) on each side of the tire equator, wherein each of the central portions, middle portions and shoulder portions has an axial width (WC, WM, WS) varying periodically while increasing and decreasing in a circumferential direction of the tire; each of the central portions being provided with a plurality of central lateral grooves to form a plurality of central blocks each having a hexagonal shaped top face, wherein each of the central lateral grooves communicates a zigzag peak (3h, 3k) of the central main groove with a zigzag peak of the middle main groove so that each central lateral groove is arranged at a location where the central portion has a minimum width; each of the middle portions being provided with a plurality of middle lateral grooves to form a plurality of middle blocks each having a hexagonal shaped top face, wherein each of the middle lateral grooves communicates a zigzag peak of the middle main groove with a zigzag peak of the shoulder main groove so that each middle lateral groove is arranged at a location where the middle portion has a minimum width; each of the shoulder portions being provided with a plurality of shoulder lateral grooves to form a plurality of shoulder blocks each having a polygonal top face, wherein each of the shoulder lateral grooves communicates a zigzag peak of the shoulder main groove with the tread edge (Te) so that each shoulder lateral groove is arranged at a location where the shoulder portion has a minimum width; each central block being provided with a central sipe extending in an axial direction of the tire; characterized in that a total that is the sum of each maximum axial width of the central portions, each maximum axial width of the middle portions, each maximum axial width of the shoulder portions, a maximum axial length of the central sipe provided on one of the central portions, and a maximum axial length of the central sipe provided on the other one of the central portions being in a range of from 1.05 to 1.31 times a tread width.