A method for refining a mapped surface mesh of a cardiac chamber, the method comprising: obtaining a mapped surface mesh of the cardiac chamber anatomy, wherein the mapped surface mesh comprises a central region representing a cardiac chamber and an outer region representing a peripheral cardiac structure connected to the cardiac chamber, and wherein the mapped surface mesh comprises a first view of an anatomical landmark within the cardiac chamber; obtaining image data of a cardiac chamber anatomy of a subject; deforming the central region of the mapped surface mesh based on a first segmentation algorithm configured according to one or more predetermined shape-constraints; deforming the outer region of the mapped surface mesh based on a second segmentation algorithm configured according to the image data, thereby generating a deformed outer region; and combining the deformed central region and the deformed outer region, thereby generating a refined mapped surface mesh, characterized in that: deforming the central region of the mapped surface mesh based on the first segmentation algorithm configured according to one or more predetermined shape-constraints comprises: deforming a mean mesh model based on the central region of the mapped surface mesh to match the central region of the mapped surface mesh, thereby generating a first deformed mean mesh model; deforming the first deformed mean mesh model based on the image data of the cardiac chamber anatomy to register the first deformed mean mesh model to the image data of the cardiac chamber anatomy, thereby generating an adapted mesh model; and deforming the central region of the mapped surface mesh based on the deformation applied to the first deformed mean mesh model, thereby generating a deformed central region. obtaining a mapped surface mesh of the cardiac chamber anatomy, wherein the mapped surface mesh comprises a central region representing a cardiac chamber and an outer region representing a peripheral cardiac structure connected to the cardiac chamber, and wherein the mapped surface mesh comprises a first view of an anatomical landmark within the cardiac chamber; obtaining image data of a cardiac chamber anatomy of a subject; deforming the central region of the mapped surface mesh based on a first segmentation algorithm configured according to one or more predetermined shape-constraints; deforming the outer region of the mapped surface mesh based on a second segmentation algorithm configured according to the image data, thereby generating a deformed outer region; and combining the deformed central region and the deformed outer region, thereby generating a refined mapped surface mesh, characterized in that: deforming the central region of the mapped surface mesh based on the first segmentation algorithm configured according to one or more predetermined shape-constraints comprises: deforming a mean mesh model based on the central region of the mapped surface mesh to match the central region of the mapped surface mesh, thereby generating a first deformed mean mesh model; deforming the first deformed mean mesh model based on the image data of the cardiac chamber anatomy to register the first deformed mean mesh model to the image data of the cardiac chamber anatomy, thereby generating an adapted mesh model; and deforming the central region of the mapped surface mesh based on the deformation applied to the first deformed mean mesh model, thereby generating a deformed central region. deforming a mean mesh model based on the central region of the mapped surface mesh to match the central region of the mapped surface mesh, thereby generating a first deformed mean mesh model; deforming the first deformed mean mesh model based on the image data of the cardiac chamber anatomy to register the first deformed mean mesh model to the image data of the cardiac chamber anatomy, thereby generating an adapted mesh model; and deforming the central region of the mapped surface mesh based on the deformation applied to the first deformed mean mesh model, thereby generating a deformed central region.