mhurhangee/ep-ind-claims huggingface dataset:
A skull implant, comprising: a rigid substrate shaped and dimensioned to replace a section of a skull, the substrate having an inner side and an outer side; at least one electrically-conductive plate (22; 32) having an inner side and an outer side, wherein the outer side of each plate (22; 32) is affixed to the inner side of the substrate; a dielectric layer (24; 34) disposed on the inner side of each plate (22; 32); and at least one electrically-conductive lead (26; 36) having an inner end and an outer end, wherein the inner end of each lead (26; 36) is disposed in electrical contact with the at least one plate (22; 32), and each lead (26; 36) passes through the substrate, with the outer end of each lead (26; 36) being configured to accept an electrical signal from an external device. a rigid substrate shaped and dimensioned to replace a section of a skull, the substrate having an inner side and an outer side; at least one electrically-conductive plate (22; 32) having an inner side and an outer side, wherein the outer side of each plate (22; 32) is affixed to the inner side of the substrate; a dielectric layer (24; 34) disposed on the inner side of each plate (22; 32); and at least one electrically-conductive lead (26; 36) having an inner end and an outer end, wherein the inner end of each lead (26; 36) is disposed in electrical contact with the at least one plate (22; 32), and each lead (26; 36) passes through the substrate, with the outer end of each lead (26; 36) being configured to accept an electrical signal from an external device.
A method of fabricating a ceramic material, the method comprising the following steps: - forming a ceramic material by performing a first chemical reaction at least between a first powder of a metallic disilicide MSi 2 where M is a transition metal and a reactive gas phase, the first chemical reaction being a nitriding reaction and the reactive gas phase comprising the element N or the first chemical reaction being a carburizing reaction and the reactive gas phase comprising the element C, a liquid phase obtained from a second powder being present around the grains of the first powder during the first chemical reaction, a working temperature being imposed during the formation of the ceramic material, which temperature is low enough to avoid melting the first powder, and one of the two following characteristics being true: - the second powder is a powder of nickel and the liquid phase is obtained as a result of a second chemical reaction between at least one element of the first powder and the nickel of the second powder; or - the second powder is a powder of an alloy of aluminum and of silicon AlSi13 comprising 13% by weight silicon and the liquid phase is obtained by melting by said alloy of aluminum and of silicon. - forming a ceramic material by performing a first chemical reaction at least between a first powder of a metallic disilicide MSi 2 where M is a transition metal and a reactive gas phase, the first chemical reaction being a nitriding reaction and the reactive gas phase comprising the element N or the first chemical reaction being a carburizing reaction and the reactive gas phase comprising the element C, a liquid phase obtained from a second powder being present around the grains of the first powder during the first chemical reaction, a working temperature being imposed during the formation of the ceramic material, which temperature is low enough to avoid melting the first powder, and one of the two following characteristics being true: - the second powder is a powder of nickel and the liquid phase is obtained as a result of a second chemical reaction between at least one element of the first powder and the nickel of the second powder; or - the second powder is a powder of an alloy of aluminum and of silicon AlSi13 comprising 13% by weight silicon and the liquid phase is obtained by melting by said alloy of aluminum and of silicon. - the second powder is a powder of nickel and the liquid phase is obtained as a result of a second chemical reaction between at least one element of the first powder and the nickel of the second powder; or - the second powder is a powder of an alloy of aluminum and of silicon AlSi13 comprising 13% by weight silicon and the liquid phase is obtained by melting by said alloy of aluminum and of silicon.
Method for coating samples by spraying with a solution using a spraying device, in which the sample is sprayed several times in succession, a subsequent spray application being carried out only once the previously applied coat has dried, characterised in that the first applied coat is sprayed with a smaller quantity of solution per surface area, the quantity is increased in the subsequent coats, until a specified quantity of solution per surface area is reached, which is applied for the last coat or repeatedly applied for several coats.
A vehicle braking system constructed and arranged to collect particles emitted during braking, said braking system comprising a caliper supporting an inner brake lining and an outer brake lining each comprising a support plate (41, 51) and a friction layer (42, 52), said inner and outer brake linings (4, 5) comprising an orifice passing through their thickness, the braking system further comprising: - an internal reservoir facing said orifice of said support plate of said internal brake lining, said internal reservoir opening onto said support plate and comprising a first magnet, - an external reservoir facing said orifice of said support plate of said external brake lining, said external reservoir opening onto said support plate and comprising a second magnet, - the faces (11, 12) of the first and second magnets (8, 10) facing said orifices being in relief, characterized in that at least one of the faces (11, 12) of the first or second magnet (8, 10) facing one of the orifices is spherical or is convex or has a chamfer. - an internal reservoir facing said orifice of said support plate of said internal brake lining, said internal reservoir opening onto said support plate and comprising a first magnet, - an external reservoir facing said orifice of said support plate of said external brake lining, said external reservoir opening onto said support plate and comprising a second magnet, - the faces (11, 12) of the first and second magnets (8, 10) facing said orifices being in relief,
A cosmetic cleansing composition comprising at least: a) one or more vegetable oil(s), in an amount of at least 0.3 pbw relative to the total weight of 100 pbw of the composition, b) from 1 pbw to 40 pbw, relative to the total weight of 100 pbw of the composition, of a surfactant system comprising at least one sultaine surfactant, c) from 1 to 5 pbw, relative to the total weight 100 pbw of the composition, of a non-ionic thickener which is a polyether endcapped by fatty acid esters with said fatty acid moiety having from 8 to 40 carbon atoms, and d) from 0.3 to 2 pbw, relative to the total weight of 100 pbw of the composition, of a non-ionic solubilizer which is a mono- or poly- alkyl or alkenyl ester of an alkoxylated fatty acid, with said fatty acid being a saturated or unsaturated hydroxylated (C8-C22) fatty acid; wherein the weight ratio between the vegetable oil and the solubilizer ranges from 1:2 to 1:1; wherein the cosmetic cleansing composition exhibits a light transmittance value at 600nm of greater than or equal to 90% and wherein the light transmittance value is measured according to the description. a) one or more vegetable oil(s), in an amount of at least 0.3 pbw relative to the total weight of 100 pbw of the composition, b) from 1 pbw to 40 pbw, relative to the total weight of 100 pbw of the composition, of a surfactant system comprising at least one sultaine surfactant, c) from 1 to 5 pbw, relative to the total weight 100 pbw of the composition, of a non-ionic thickener which is a polyether endcapped by fatty acid esters with said fatty acid moiety having from 8 to 40 carbon atoms, and d) from 0.3 to 2 pbw, relative to the total weight of 100 pbw of the composition, of a non-ionic solubilizer which is a mono- or poly- alkyl or alkenyl ester of an alkoxylated fatty acid, with said fatty acid being a saturated or unsaturated hydroxylated (C8-C22) fatty acid; wherein the weight ratio between the vegetable oil and the solubilizer ranges from 1:2 to 1:1; wherein the cosmetic cleansing composition exhibits a light transmittance value at 600nm of greater than or equal to 90% and wherein the light transmittance value is measured according to the description.
An object recognition method using a sensor configured to acquire a position of an object existing in a surrounding environment as point clouds including a plurality of detection points in a top view, the method comprising: grouping the point clouds according to a proximity; determining, when performing polygon approximation on the grouped point clouds, whether or not at least part of the detection points constituting the grouped point clouds is located in a blind zone of an approximate polygon acquired by the polygon approximation on the point clouds with respect to the sensor, wherein the blind zone is defined as sides of the approximate polygon which cannot be observed by the sensor, so as to recognize whether an object having an outer shape corresponding to the polygon actually exists in the top view at a position of the approximate polygon; recognizing the grouped point clouds as point clouds corresponding to plural objects when it is determined that the part of the detection points is located in the blind zone with respect to the sensor; and recognizing the grouped point clouds as point clouds corresponding to a single object of the approximate polygon when it is determined that the part of the detection points is not located in the blind zone with respect to the sensor. grouping the point clouds according to a proximity; determining, when performing polygon approximation on the grouped point clouds, whether or not at least part of the detection points constituting the grouped point clouds is located in a blind zone of an approximate polygon acquired by the polygon approximation on the point clouds with respect to the sensor, wherein the blind zone is defined as sides of the approximate polygon which cannot be observed by the sensor, so as to recognize whether an object having an outer shape corresponding to the polygon actually exists in the top view at a position of the approximate polygon; recognizing the grouped point clouds as point clouds corresponding to plural objects when it is determined that the part of the detection points is located in the blind zone with respect to the sensor; and recognizing the grouped point clouds as point clouds corresponding to a single object of the approximate polygon when it is determined that the part of the detection points is not located in the blind zone with respect to the sensor.
A method of generating an immunotherapeutic composition for use in the treatment of a virus-associated tumour from a patient, the method comprising: analyzing, a biopsy sample that has been obtained from the virus-associated tumour of the patient, and identifying a non-patient nucleic acid in the virus-associated tumour; determining a plurality of nucleic acid sequences encoding patient-specific and tumour-specific neoepitopes for the virus-associated tumour by identifying positions in which the non-patient nucleic acid differs from a reference nucleic acid of a virus known to be related to the virus-associated tumour, wherein each of the neoepitopes has a length of between 5 and 30 amino acids, and wherein the non-patient nucleic acid includes a mutation compared to the reference nucleic acid of the virus related to the virus-associated tumour; identifying an HLA-matched neoepitope from the plurality of patient-specific and tumour-specific neoepitopes, wherein the HLA-matched neoepitope has a dissociation constant equal to or less than 100 nM with an HLA-type of the patient; and generating the patient-specific immunotherapeutic composition comprising a recombinant virus that includes the nucleic acid encoding the HLA-matched neoepitope. analyzing, a biopsy sample that has been obtained from the virus-associated tumour of the patient, and identifying a non-patient nucleic acid in the virus-associated tumour; determining a plurality of nucleic acid sequences encoding patient-specific and tumour-specific neoepitopes for the virus-associated tumour by identifying positions in which the non-patient nucleic acid differs from a reference nucleic acid of a virus known to be related to the virus-associated tumour, wherein each of the neoepitopes has a length of between 5 and 30 amino acids, and wherein the non-patient nucleic acid includes a mutation compared to the reference nucleic acid of the virus related to the virus-associated tumour; identifying an HLA-matched neoepitope from the plurality of patient-specific and tumour-specific neoepitopes, wherein the HLA-matched neoepitope has a dissociation constant equal to or less than 100 nM with an HLA-type of the patient; and generating the patient-specific immunotherapeutic composition comprising a recombinant virus that includes the nucleic acid encoding the HLA-matched neoepitope.
An interface (180,189,200) for coupling a patient's eye to an ophthalmic surgical laser system, the interface comprising: a lens cone defining a first plane surface coupled with a delivery tip of the ophthalmic laser system, the lens cone further comprising: an apex ring coupled to the first plane surface, the apex ring comprising a distal end; characterised by a first receptacle configured to receive an attachment ring, the attachment ring configured to overlay an anterior surface of the patient's eye; a central cavity configured to receive the lens cone; and one or more beam-splitter optics configured to allow a pulsed laser beam to pass through the interface to a focal point of the target in the patient's eye. a lens cone defining a first plane surface coupled with a delivery tip of the ophthalmic laser system, the lens cone further comprising: an apex ring coupled to the first plane surface, the apex ring comprising a distal end; characterised by a first receptacle configured to receive an attachment ring, the attachment ring configured to overlay an anterior surface of the patient's eye; a central cavity configured to receive the lens cone; and one or more beam-splitter optics configured to allow a pulsed laser beam to pass through the interface to a focal point of the target in the patient's eye.
Composite comprising at least one reinforcing element exhibiting a surface comprising an alloy of copper and zinc, said reinforcing element being embedded in an elastomeric composition based on at least a diene elastomer, a reinforcing filler, a sulfur crosslinking system and a phenol/aldehyde resin based: - on at least one aromatic polyphenol comprising at least one aromatic nucleus bearing at least two hydroxyl functions in the meta position with respect to each other, the two positions ortho to at least one of the hydroxyl functions being unsubstituted, and - on at least one dialdehyde compound comprising two aldehyde functions, in which the content of phenol/aldehyde resin is less than 10 phr, preferably less than 6 phr. - on at least one aromatic polyphenol comprising at least one aromatic nucleus bearing at least two hydroxyl functions in the meta position with respect to each other, the two positions ortho to at least one of the hydroxyl functions being unsubstituted, and - on at least one dialdehyde compound comprising two aldehyde functions,
A thermal transfer printer comprising: first and second spool supports (8a, 9a) each being configured to support a spool of ribbon (5, 7); a ribbon drive (8, 9) configured to cause movement of ribbon from the first spool support to the second spool support; a printhead configured to selectively transfer ink from the ribbon to a substrate, the printhead pressing the print ribbon and substrate together against a print roller; a substrate drive configured to cause movement of the substrate past the printhead; a sensor configured to monitor rotation of the print roller and generate a signal indicative thereof; and a controller configured to determine a measure of movement of the substrate and/or ribbon past the print roller based upon the signal output by the sensor and a quantity indicative of a diameter of the print roller; wherein the quantity indicative of the diameter of the print roller is a quantity indicative of an effective diameter of the print roller as determined by the controller based upon a quantity indicative of the pressure applied by the printhead to the ribbon and the substrate against the print roller. first and second spool supports (8a, 9a) each being configured to support a spool of ribbon (5, 7); a ribbon drive (8, 9) configured to cause movement of ribbon from the first spool support to the second spool support; a printhead configured to selectively transfer ink from the ribbon to a substrate, the printhead pressing the print ribbon and substrate together against a print roller; a substrate drive configured to cause movement of the substrate past the printhead; a sensor configured to monitor rotation of the print roller and generate a signal indicative thereof; and a controller configured to determine a measure of movement of the substrate and/or ribbon past the print roller based upon the signal output by the sensor and a quantity indicative of a diameter of the print roller; wherein the quantity indicative of the diameter of the print roller is a quantity indicative of an effective diameter of the print roller as determined by the controller based upon a quantity indicative of the pressure applied by the printhead to the ribbon and the substrate against the print roller.
Adjustment drive (5, 6) for a steering column for a motor vehicle, comprising a threaded spindle (52, 62) which extends axially longitudinally in the direction of a spindle axis and engages in a spindle nut (51, 61), and a drive unit (55, 65) which is coupled to the threaded spindle (52, 62) or the spindle nut (51, 61) in such a way that the threaded spindle (52, 62) and the spindle nut (51, 61) can be driven in rotation relative to one another, wherein a stop device for limiting an axial movement of the spindle nut (51, 61) relative to the threaded spindle (52, 62) having at least one stop surface supported in the axial direction on the threaded spindle (51, 61), and a mating surface directed axially against the stop surface, and supported on the spindle nut (51, 61), characterized in that the stop device has a disengaging device, the disengaging device having the stop surface and the latter being supported against the threaded spindle via the disengaging device such that it can be adjusted in the axial direction, and/or the disengaging device having the mating surface which is supported against the spindle nut via the disengaging device such that it can be adjusted in the axial direction.
interface for dental prosthetics to be placed on at least one implant comprising: - an area of contact with the implant which comprises a first shaft which coincides with the shaft of the implant, - a sloping area which comprises a second shaft and a sloping face, and - an internal orifice in the two areas (2, 3), in such a way that the first shaft and the second shaft intersect and form an angle at the intersection where the area of contact and the sloping area make a one-piece interface; characterised in that the internal orifice comprises: - a first part in the sloping area, and - a second part in the contact area, in such a way that the first part has the shape of a first truncated cone sector and the second part has the shape of a second truncated cone sector, in which at least one generatrix of the first truncated cone sector in the first part of the internal orifice is a continuation of a generatrix of the second truncated cone sector in the second part of the internal orifice, in such a way that both truncated cones share the base. - an area of contact with the implant which comprises a first shaft which coincides with the shaft of the implant, - a sloping area which comprises a second shaft and a sloping face, and - an internal orifice in the two areas (2, 3), - a first part in the sloping area, and - a second part in the contact area,
Use of a peptide comprising a sequence defined by SEQ ID NO: 1, SEQ ID NO: 2 or SEQ ID NO: 3, for detecting in the serum of a HCV-infected patient the presence of specific antibodies able to react simultaneously with the three regions of E1 and E2 that are recognized by the monoclonal antibody secreted by the hybridoma desposited at the CNCM (Collection Nationale de Culture de Microorganismes, Institut Pasteur, Paris, France) on March 19, 2003, under accession number CNCM 1-2983, wherein said three regions of E1 and E2 are constituted of each of the following sequences: - amino acids 297 to 306 of HCV protein E1 (SEQ ID NO: 1); - amino acids 480 to 494 of HCV protein E2 (SEQ ID NO: 2); and - amino acids 613 to 621 of HCV protein E2 (SEQ ID NO: 3). - amino acids 297 to 306 of HCV protein E1 (SEQ ID NO: 1); - amino acids 480 to 494 of HCV protein E2 (SEQ ID NO: 2); and - amino acids 613 to 621 of HCV protein E2 (SEQ ID NO: 3).
Method for manufacturing a rubber profiled-element portion (P3, P5, P7, P9, P11, P13), wherein the following steps are implemented: - Step A: a strip of unvulcanized rubber of given constant, substantially triangular, section is delivered, - Step B: the strip is stretched by an elongation percentage that is variable according to a predetermined law, so as to give the strip a reduced section, - Step C: said profiled-element portion (P3, P5, P7, P9, P11, P13) is produced by winding the strip of reduced section on itself on a rotating building drum without modifying the transverse position of the longitudinal axis of the strip. - Step A: a strip of unvulcanized rubber of given constant, substantially triangular, section is delivered, - Step B: the strip is stretched by an elongation percentage that is variable according to a predetermined law, so as to give the strip a reduced section, - Step C: said profiled-element portion (P3, P5, P7, P9, P11, P13) is produced by winding the strip of reduced section on itself on a rotating building drum without modifying the transverse position of the longitudinal axis of the strip.