mhurhangee/ep-ind-claims huggingface dataset:
A system, comprising: an inner tube; an outer tube at least partially surrounding the inner tube so that a medical device can be positioned between the inner and outer tubes (140, 130), the inner and outer tubes (140, 130) being configured to be capable of being disposed within a body lumen; and an actuator configured so that, as a force is applied to the actuator, the actuator causes relative motion between the inner and outer tubes (140, 130), wherein a mechanical advantage of the actuator changes as the actuator moves, characterized in that the actuator comprises a rotatable member having a radius that increases as the actuator rotates, wherein the system further comprises a windable member that couples the rotatable member to the outer tube, and wherein the system further comprises a rotatable element coupled to the rotatable member so that, as the rotatable element rotates, the rotatable member rotates. an inner tube; an outer tube at least partially surrounding the inner tube so that a medical device can be positioned between the inner and outer tubes (140, 130), the inner and outer tubes (140, 130) being configured to be capable of being disposed within a body lumen; and an actuator configured so that, as a force is applied to the actuator, the actuator causes relative motion between the inner and outer tubes (140, 130), wherein a mechanical advantage of the actuator changes as the actuator moves, characterized in that the actuator comprises a rotatable member having a radius that increases as the actuator rotates, wherein the system further comprises a windable member that couples the rotatable member to the outer tube, and wherein the system further comprises a rotatable element coupled to the rotatable member so that, as the rotatable element rotates, the rotatable member rotates.
A PD-L1 antagonist for use in a method for treating or delaying progression of melanoma that is resistant to a B-raf antagonist in an individual, wherein the PD-L1 antagonist is administered in combination with a MEK inhibitor, wherein the individual has been previously treated with the B-raf antagonist for melanoma, wherein the B-raf antagonist is vemurafenib, wherein the PD-L1 antagonist is an anti-PD-Ll antibody, and wherein the MEK inhibitor is or a pharmaceutically acceptable salt or solvate thereof.
A positive-working lithographic printing plate precursor comprising a substrate having thereon an image forming layer comprising a water-insoluble resin which is soluble or dispersible in an aqueous alkali solution, wherein the positive-working lithographic printing plate precursor further comprises a photothermal conversion material, and the resin, which is water-insoluble and soluble or dispersible in the aqueous alkali solution, comprises a polyurethane having a weight average molecular weight within the range from 2,000 to 100,000 and including a unit comprising a substituent having an acidic hydrogen atom and a unit represented by the following general formula: wherein R f is a fluorinated alkyl or polyether group in which at least 50% of hydrogen atoms have been fluorinated, R 1 is a hydrogen atom, or a substituted or non-substituted alkyl group, m is 0 or 1 to 10, n is 1 to 30, and x is 1 to 4; wherein the content of the polyurethane is within the range from 2 to 99.4% by weight based on the solid content of the image forming layer. R f is a fluorinated alkyl or polyether group in which at least 50% of hydrogen atoms have been fluorinated, R 1 is a hydrogen atom, or a substituted or non-substituted alkyl group, m is 0 or 1 to 10, n is 1 to 30, and x is 1 to 4; wherein the content of the polyurethane is within the range from 2 to 99.4% by weight based on the solid content of the image forming layer.
A microparticle sorting device comprising: an orifice configured to discharge fluid including sheath liquid and sample liquid; an oscillation element configured to give oscillation to convert the fluid into fluid droplets; an imaging element configured to obtain an image of the fluid and the fluid droplets; and a processor configured to determine a constricted width of the constricted region of the fluid right before being converted into fluid droplets from the image, characterized in that the processor is further configured to control a drive voltage for the oscillation element such that the constricted width of the fluid meets a reference constricted width. an orifice configured to discharge fluid including sheath liquid and sample liquid; an oscillation element configured to give oscillation to convert the fluid into fluid droplets; an imaging element configured to obtain an image of the fluid and the fluid droplets; and a processor configured to determine a constricted width of the constricted region of the fluid right before being converted into fluid droplets from the image, characterized in that the processor is further configured to control a drive voltage for the oscillation element such that the constricted width of the fluid meets a reference constricted width.
A method for joining together different components (11, 12) or different sections of a single component (11, 12), comprising the steps of: a) providing one or more components (11, 12), wherein at least one of the components (11, 12) is a thermoplastic fiber composite component, to be joined together at one or more positions, and at least one component of a fastener, b) positioning said one or more components (11, 12), or sections of the single component (11, 12), on top of each other, c) heating at least a portion of the at least one thermoplastic fiber composite component, and optionally also portions of the other components to be joined, at one or more positions where the components are to be joined and/or heating said at least one component of the fastener, and d) drilling said at least one component of the fastener into at least the bottom component at the one or more positions, wherein a further component of the fastener is fixed to said at least one component of a fastener, to join the component(s) (11, 12) together, wherein step (c) can be performed prior to and/or during step (d), characterized in that said at least one component of the fastener comprises a thread and is an insert screwed into the bottom component, and the further component is a bolt. a) providing one or more components (11, 12), wherein at least one of the components (11, 12) is a thermoplastic fiber composite component, to be joined together at one or more positions, and at least one component of a fastener, b) positioning said one or more components (11, 12), or sections of the single component (11, 12), on top of each other, c) heating at least a portion of the at least one thermoplastic fiber composite component, and optionally also portions of the other components to be joined, at one or more positions where the components are to be joined and/or heating said at least one component of the fastener, and d) drilling said at least one component of the fastener into at least the bottom component at the one or more positions,
A laser light supply system for fiber-optic data communication, comprising: a laser light generator configured to simultaneously generate a plurality of wavelengths of continuous wave laser light, the laser light generator having an optical output, the laser light generator configured to transmit each of the plurality of wavelengths of continuous wave laser light through the optical output as a laser light supply, wherein the laser light generator includes a plurality of lasers, each laser in the plurality of lasers (501-1 to 501-N) configured to generate continuous wave laser light at a different wavelength, wherein each laser in the plurality of lasers (501-1 to 501-N) is mounted in thermal contact with a common thermally conductive substrate configured to distribute heat emanating from each laser in the plurality of lasers, wherein each laser in the plurality of lasers (501-1 to 501-N) does not have active temperature control; an optical conveyance device (305, 511) connected to receive the laser light supply from the optical output of the laser light generator; and an optical distribution network having an optical input connected to the optical conveyance device (305, 511) to receive the laser light supply from the laser light generator, the optical distribution network configured to transmit the laser light supply to each of one or more optical transceivers (311-1 to 311-N), wherein the laser light generator is physically separate from each of the one or more optical transceivers (311-1 to 311-N). a laser light generator configured to simultaneously generate a plurality of wavelengths of continuous wave laser light, the laser light generator having an optical output, the laser light generator configured to transmit each of the plurality of wavelengths of continuous wave laser light through the optical output as a laser light supply, wherein the laser light generator includes a plurality of lasers, each laser in the plurality of lasers (501-1 to 501-N) configured to generate continuous wave laser light at a different wavelength, wherein each laser in the plurality of lasers (501-1 to 501-N) is mounted in thermal contact with a common thermally conductive substrate configured to distribute heat emanating from each laser in the plurality of lasers, wherein each laser in the plurality of lasers (501-1 to 501-N) does not have active temperature control; an optical conveyance device (305, 511) connected to receive the laser light supply from the optical output of the laser light generator; and an optical distribution network having an optical input connected to the optical conveyance device (305, 511) to receive the laser light supply from the laser light generator, the optical distribution network configured to transmit the laser light supply to each of one or more optical transceivers (311-1 to 311-N), wherein the laser light generator is physically separate from each of the one or more optical transceivers (311-1 to 311-N).
Use of an aqueous composition comprising (i) an aqueous solvent, (ii) gellan gum and (iii) Hydroxypropyl methylcellulose (HPMC), wherein the gellan gum and HPMC are present in a weight ratio of between 4/100 and 15/100 (lower and upper limits included), wherein the aqueous composition does not comprise additional gelling aids comprising cations, wherein cations are not present in an amount higher than the amount naturally present in the gellan gum, to impart acid resistance to hard pharmaceutical capsule shells and capsules, wherein said capsule does not leak at pH 1.2 in a USP-30 simulated gastric fluid for at least 1 hour.
A document feeding device for feeding documents, comprising: a document input tray configured such that documents to be fed are placed thereon; a document output tray configured to receive the documents having been ejected; and a feeding mechanism (41, 42,..., 49, 50, 51) which is provided for a feeding path connecting the document input tray and the document output tray via a scanning position and feeds each document from the document input tray to the scanning position and from the scanning position to the document output tray, wherein the document output tray includes: a tray part which holds the ejected documents; a projecting part formed substantially in a mountain shape on a holding surface of the tray part on an upstream side in a feeding direction which pushes up a part of the ejected documents on the upstream side in the feeding direction and thereby lifts an upstream end of the ejected documents; and characterized by a pressing member configured to contact the ejected documents from above at a position on the downstream side of the projecting part's apex in the feeding direction, so that when the rear part of the ejected documents is pushed up by the projecting part, the sliding of each following document under the ejected documents is facilitated. a document input tray configured such that documents to be fed are placed thereon; a document output tray configured to receive the documents having been ejected; and a feeding mechanism (41, 42,..., 49, 50, 51) which is provided for a feeding path connecting the document input tray and the document output tray via a scanning position and feeds each document from the document input tray to the scanning position and from the scanning position to the document output tray, wherein the document output tray includes: a tray part which holds the ejected documents; a projecting part formed substantially in a mountain shape on a holding surface of the tray part on an upstream side in a feeding direction which pushes up a part of the ejected documents on the upstream side in the feeding direction and thereby lifts an upstream end of the ejected documents; and characterized by a pressing member configured to contact the ejected documents from above at a position on the downstream side of the projecting part's apex in the feeding direction, so that when the rear part of the ejected documents is pushed up by the projecting part, the sliding of each following document under the ejected documents is facilitated. a tray part which holds the ejected documents; a projecting part formed substantially in a mountain shape on a holding surface of the tray part on an upstream side in a feeding direction which pushes up a part of the ejected documents on the upstream side in the feeding direction and thereby lifts an upstream end of the ejected documents; and characterized by a pressing member configured to contact the ejected documents from above at a position on the downstream side of the projecting part's apex in the feeding direction, so that when the rear part of the ejected documents is pushed up by the projecting part, the sliding of each following document under the ejected documents is facilitated.
A method of differentiating cells in a cell culture, said method comprising: (a) contacting a cell culture comprising human pluripotent cells with a medium comprising less than about 2% serum, (b) providing said human pluripotent cells with a growth factor of the TGFβ superfamily wherein the growth factor of the TGFβ superfamily is selected from the group consisting of activin A and activin B, and (c) permitting differentiation of said human pluripotent cells to occur to mesendoderm cells. (a) contacting a cell culture comprising human pluripotent cells with a medium comprising less than about 2% serum, (b) providing said human pluripotent cells with a growth factor of the TGFβ superfamily wherein the growth factor of the TGFβ superfamily is selected from the group consisting of activin A and activin B, and (c) permitting differentiation of said human pluripotent cells to occur to mesendoderm cells.
Lighting system, comprising at least one duct, for receiving at least one lighting unit (4; 104, 104a-b; 204; 304; 404; 504; 604; 704a-b) which is insertable into the duct, and comprising at least one connector which is insertable into the duct, wherein the duct has, in an inner region (9; 9'; 9"; 9"'; 9"") thereof, a busbar for powering the lighting unit (4; 104, 104a-b; 204; 304; 404; 504; 604; 704a-b), which is electrically couplable to the busbar; wherein the lighting unit (4; 104, 104a-b; 204; 304; 404; 504; 604; 704a-b) has a light supply and optics unit (12; 112, 112a-b; 212; 312; 612; 712a-b) and at least one power unit, wherein the power unit has contacting means, which facilitate the electrical coupling of the lighting unit (4; 104, 104a-b; 204; 304; 404; 504; 604; 704a-b) to the busbar, wherein the power unit is electrically coupled to the light supply and optics unit (12; 112, 112a-b; 212; 312; 612; 712a-b), and wherein the power unit further has a housing unit which is mechanically coupled to the light supply and optics unit (12; 112; 112a-b; 212; 312; 612; 712a-b); wherein the connector is configured for electrically coupling busbar portions of the busbar to one another, and wherein the connector is set up for mechanical coupling to portions of the duct; wherein the duct and the connector are configured in such a way that the lighting unit (4; 104, 104a-b; 204; 304; 404; 504; 604; 704a-b), when inserted into the duct, can be arranged overlapping, within the duct, with the connector which is inserted into the duct for coupling the busbar portions; and wherein the housing element of the power unit projects, in a direction which extends parallel to a depth direction of the duct when the lighting unit (4; 104, 104a-b; 204; 304; 404; 504; 604; 704a-b) is inserted, substantially as far past the light supply and optics unit (12; 112, 112a-b; 212; 312; 612; 712a-b) as a housing of the connector extends in a thickness direction of the connector.
An umbilical comprising a plurality of longitudinal strength members, said strength members having one or more varying characteristics along the length of the umbilical, and wherein the longitudinal strength members comprise sequentially at least a first section having a first characteristic(s) extending from one end of the umbilical, a transition zone, and a second section having a second and different characteristic(s) to the first section, characterised in that at least one of the strength members comprises first and second sections selected from the group comprising: a steel rope section and a polymeric filler section; a composite rod section and a polymer filler section; a high strength fibre rope section and a polymeric filler section; and a steel rod section and a polymer filler section. a steel rope section and a polymeric filler section; a composite rod section and a polymer filler section; a high strength fibre rope section and a polymeric filler section; and a steel rod section and a polymer filler section.
An electronic installation device for controlling a load in an electric circuit, said electronic installation device having a single-layer or multilayer circuit board arrangement having electrical components and conductor tracks and said electronic installation device comprising a load circuit and a control circuit which are at least functionally coupled to one another, wherein the electronic installation device has an overcurrent protection device for protection against overload currents, characterized in that the load circuit has an overcurrent protection device for protection against short-circuit currents, a resistor element and a circuit interruption element that can be arranged in series between a current source and an electrical load.
A measurement device for measuring a process variable using a specified maximum power consumption by measurement device, comprising a control device (302, 402, 502, 602, 802, 902, 1002, 1102, 1202, 1302; 403, 603, 903, 1103, 1203, 1303; 106, 206, 706) for controlling the measurement operation of the measurement device for an adaption to the specified power consumption, wherein the control device (302, 402, 502, 602, 802, 902, 1002, 1102, 1202, 1302; 403, 603, 903, 1103, 1203, 1303; 106, 206, 706) controls the power consumption for the measurement operation of the measurement device (101, 201, 301, 401, 501, 601, 701, 801, 901, 1001, 1101, 1201, 1301) such that the control device (302, 402, 502, 602, 802, 902, 1002, 1102, 1202, 1302; 403, 603, 903, 1103, 1203, 1303; 106, 206, 706) causes this power consumption to approach the specified power consumption without exceeding the specified power consumption, wherein the specified power consumption is defined by a specified current, and wherein the control device (302, 402, 502, 602, 802, 902, 1002, 1102, 1202, 1302; 403, 603, 903, 1103, 1203, 1303; 106, 206, 706) adjusts the power demand for the measurement operation of the measurement device depending on the specified current, and wherein the control device measures or estimates a power excess by means of which the specified power consumption of the measurement device exceeds the power consumption for the measurement operation, and after determining the actual power excess causes the power consumption of the measurement device to approach the specified power consumption by means of the type and the frequency of the execution of the measurement cycle, such that the power excess is minimized, and wherein the control device decreases the frequency of the execution of the measurement cycle for a reduction of the power excess and increases the frequency of the execution of the measurement cycle for an increase of the power excess.
A computer implemented method, comprising: configuring a shared buffer in response to first configuration data to support processing of a first read stream and a second read stream, wherein the first read stream is associated with a first video codec format, and wherein the second read stream is associated with a second video codec format different than the first video codec format; determining a first buffer write address within the shared buffer in response to a memory request associated with the first read stream; and subsequently, determining whether the shared buffer needs to be reconfigured to support processing of the second read stream; reconfiguring the shared buffer in response to second configuration data to support processing of the second read stream; determining a second buffer write address within the shared buffer in response to a memory request associated with the second read stream, wherein the second buffer write address is different than the first buffer write address wherein configuring the shared buffer to support processing of the first read stream and the second read stream comprises configuring the shared buffer in response to the first configuration data and the second configuration data, wherein the configuration data was provided by a first software driver associated with the first read stream and by a second software driver associated with the second read stream. configuring a shared buffer in response to first configuration data to support processing of a first read stream and a second read stream, wherein the first read stream is associated with a first video codec format, and wherein the second read stream is associated with a second video codec format different than the first video codec format; determining a first buffer write address within the shared buffer in response to a memory request associated with the first read stream; and subsequently, determining whether the shared buffer needs to be reconfigured to support processing of the second read stream; reconfiguring the shared buffer in response to second configuration data to support processing of the second read stream; determining a second buffer write address within the shared buffer in response to a memory request associated with the second read stream, wherein the second buffer write address is different than the first buffer write address wherein configuring the shared buffer to support processing of the first read stream and the second read stream comprises configuring the shared buffer in response to the first configuration data and the second configuration data, wherein the configuration data was provided by a first software driver associated with the first read stream and by a second software driver associated with the second read stream.