mhurhangee/ep-ind-claims huggingface dataset:
Process for the preparation of a bioconjugate, the process comprising the step of conjugating a glycoprotein with a linker-conjugate, by reacting a reactive group Q 1 of the linker-conjugate with a functional group F 1 of the glycoprotein, wherein the linker-conjugate is a compound comprising an alpha-end and an omega-end, the compound comprising on the alpha-end a reactive group Q 1 capable of reacting with a functional group F 1 present on the glycoprotein and on the omega-end a target molecule selected from the group consisting of a drug, a prodrug, a diagnostic agent, a protein, a peptide, a polypeptide, a peptide tag, an amino acid, a glycan, a lipid, a vitamin, a steroid, a nucleotide, a nucleoside, a polynucleotide, RNA, DNA, a reporter molecule, a polymer, a solid surface, a hydrogel, a nanoparticle, a microparticle and a biomolecule, wherein Q 1 is a reactive group selected from the group consisting of, optionally substituted, N-maleimidyl groups, halogenated N-alkylamido groups, activated ester groups, thiol groups, alkynyl groups, (hetero)cycloalkynyl groups, tetrazinyl groups, azido groups, phosphine groups, 1,1-bis(sulfonylmethyl)-methylcarbonyl groups, 1,2-quinone groups or triazine groups, the compound further comprising a group according to formula or a salt thereof: wherein: a is 0 or 1; and R 1 is selected from the group consisting of hydrogen, C 1 - C 24 alkyl groups, C 3 - C 24 cycloalkyl groups, C 2 - C 24 (hetero)aryl groups, C 3 - C 24 alkyl(hetero)aryl groups and C 3 - C 24 (hetero)arylalkyl groups, the C 1 - C 24 alkyl groups, C 3 - C 24 cycloalkyl groups, C 2 - C 24 (hetero)aryl groups, C 3 - C 24 alkyl(hetero)aryl groups and C 3 - C 24 (hetero)arylalkyl groups optionally substituted and optionally interrupted by one or more heteroatoms selected from O, S and NR 3 wherein R 3 is independently selected from the group consisting of hydrogen and C 1 - C 4 alkyl groups, or R 1 is a second target molecule D, wherein the second target molecule is optionally connected to N via a spacer moiety; and wherein the group according to formula, or the salt thereof, is situated in between said alpha-end and said omega-end of the compound. a is 0 or 1; and R 1 is selected from the group consisting of hydrogen, C 1 - C 24 alkyl groups, C 3 - C 24 cycloalkyl groups, C 2 - C 24 (hetero)aryl groups, C 3 - C 24 alkyl(hetero)aryl groups and C 3 - C 24 (hetero)arylalkyl groups, the C 1 - C 24 alkyl groups, C 3 - C 24 cycloalkyl groups, C 2 - C 24 (hetero)aryl groups, C 3 - C 24 alkyl(hetero)aryl groups and C 3 - C 24 (hetero)arylalkyl groups optionally substituted and optionally interrupted by one or more heteroatoms selected from O, S and NR 3 wherein R 3 is independently selected from the group consisting of hydrogen and C 1 - C 4 alkyl groups, or R 1 is a second target molecule D, wherein the second target molecule is optionally connected to N via a spacer moiety; and wherein the group according to formula, or the salt thereof, is situated in between said alpha-end and said omega-end of the compound.
A sprocket assembly, comprising: a sprocket carrier, the sprocket carrier defining a plurality of fixing apertures for use in securing a sprocket to the sprocket carrier, a sprocket, the sprocket defining a plurality of fixing apertures for use in securing the sprocket to a sprocket carrier, and a securing arrangement for releasably securing the sprocket to the sprocket carrier; wherein said securing arrangement comprises a plurality of fixing devices; characterised in that each of said plurality of fixing devices comprises a bolt and a nut, the bolt having a head portion, a threaded shank portion and a knurled shank portion, the knurled shank portion disposed between the threaded shank portion and the head portion, and the nut engageable with the threaded shank portion of the bolt (60 1); the bolt of each of said plurality of fixing devices insertable through one of the plurality of fixing apertures of the sprocket carrier into a fitted condition in which the bolt is retained within the sprocket carrier by an interference fit between the knurled shank portion of the bolt and the sprocket carrier. a sprocket carrier, the sprocket carrier defining a plurality of fixing apertures for use in securing a sprocket to the sprocket carrier, a sprocket, the sprocket defining a plurality of fixing apertures for use in securing the sprocket to a sprocket carrier, and a securing arrangement for releasably securing the sprocket to the sprocket carrier; wherein said securing arrangement comprises a plurality of fixing devices; characterised in that each of said plurality of fixing devices comprises a bolt and a nut, the bolt having a head portion, a threaded shank portion and a knurled shank portion, the knurled shank portion disposed between the threaded shank portion and the head portion, and the nut engageable with the threaded shank portion of the bolt (60 1); the bolt of each of said plurality of fixing devices insertable through one of the plurality of fixing apertures of the sprocket carrier into a fitted condition in which the bolt is retained within the sprocket carrier by an interference fit between the knurled shank portion of the bolt and the sprocket carrier.
A supporting structure of a closing resistor for a high voltage circuit breaker, the structure comprising: a fixed part main circuit conductor; a supporting conductor installed on an upper surface of the fixed part main circuit conductor; a connecting conductor connected to one end of the supporting conductor; a closing resistor unit coupled to one side of the fixed part main circuit conductor with being spaced apart therefrom; and a coupling conductor provided to couple the supporting conductor and the closing resistor unit to each other, characterised in that the supporting conductor and the connecting conductor are provided with a coupling rib and a coupling groove, respectively, to be coupled to each other in an inserting manner. a fixed part main circuit conductor; a supporting conductor installed on an upper surface of the fixed part main circuit conductor; a connecting conductor connected to one end of the supporting conductor; a closing resistor unit coupled to one side of the fixed part main circuit conductor with being spaced apart therefrom; and a coupling conductor provided to couple the supporting conductor and the closing resistor unit to each other,
Illumination module for a coordinate measuring machine for measuring a workpiece by means of an optical sensor, wherein the illumination module comprises a main body having a sensor side and a workpiece side, wherein the illumination module comprises on the main body at least one illumination arrangement (88, 104, 106) for illuminating the workpiece, and wherein the at least one illumination arrangement (88, 104, 106) has an emission characteristic (126, 130) with an emission angle and a light intensity profile within the emission angle, wherein the light intensity profile of the at least one illumination arrangement (88, 104, 106) within the emission angle is asymmetrical, characterized in that in that the emission characteristic (126, 130) of each illumination arrangement (88, 104, 106) is modulated in such a way that it has a first partial region and a second partial region, wherein there is a shadow region between the first partial region and the second partial region, and wherein the first partial regions of the at least one illumination arrangement (88, 104, 106) coincide in a first working region and second partial regions of the at least one illumination arrangement (88, 104, 106) coincide with a second working region, and in that the at least one illumination arrangement (88, 104, 106) has in each case at least one optical element (90, 92, 93, 94, 103, 136, 150) which modulates the emission characteristic (126, 130) of the respective illumination arrangement (88, 104, 106).
A fire-extinguishing facility comprising - at least one extinguishing fluid line (13,15) for conveying an extinguishing fluid, wherein, starting from a main line, the extinguishing fluid line is divided into two or more secondary distributor lines, a first of which leads into a first zone (Z 1), and a second one of which leads into a second zone (Z 2), wherein the secondary distributor lines are used within their respective zones (Z 1, Z 2) as extinguishing fluid lines for lines branching off therefrom in the manner of a network having a plurality of sprinklers (3,3') in fluid communication with the extinguishing fluid line (13, 15) which are closed in a standby state and open in an extinguishing state in order to supply the extinguishing fluid, and - a flow-measuring device associated with the extinguishing fluid line (13,15), wherein the flow-measuring device is arranged in one of the secondary distributor lines or directly in the main line and is designed to approximately quantitatively detect a volume flow of the extinguishing fluid transported in the extinguishing fluid line (13, 15) in the extinguishing state, and characterized by an evaluation unit which is configured to assign a number of open sprinklers to the approximately quantitatively detected volume flow. - at least one extinguishing fluid line (13,15) for conveying an extinguishing fluid, wherein, starting from a main line, the extinguishing fluid line is divided into two or more secondary distributor lines, a first of which leads into a first zone (Z 1), and a second one of which leads into a second zone (Z 2), wherein the secondary distributor lines are used within their respective zones (Z 1, Z 2) as extinguishing fluid lines for lines branching off therefrom in the manner of a network having a plurality of sprinklers (3,3') in fluid communication with the extinguishing fluid line (13, 15) which are closed in a standby state and open in an extinguishing state in order to supply the extinguishing fluid, and - a flow-measuring device associated with the extinguishing fluid line (13,15), wherein the flow-measuring device is arranged in one of the secondary distributor lines or directly in the main line and is designed to approximately quantitatively detect a volume flow of the extinguishing fluid transported in the extinguishing fluid line (13, 15) in the extinguishing state, and characterized by an evaluation unit which is configured to assign a number of open sprinklers to the approximately quantitatively detected volume flow.
An optoelectronic sensor for determining the distance of an object in a monitoring area, the sensor comprising a light transmitter for transmitting transmitted light, a light receiver for generating a received signal from remitted light that is remitted at the object, and a control and evaluation unit configured to modulate the transmitted light with at least a first frequency and a second frequency, to determine a phase offset between the transmitted light and the remitted light for the first frequency and the second frequency and, from this, to determine a light time of flight and, from the received signal, a first amplitude and a second amplitude for the first and the second frequencies, characterized in that the control and evaluation unit is further configured to detect an edge hit by means of an evaluation of the first amplitude and the second amplitude in the event of a difference in the amplitudes that is larger than due to noise, and to localize an object in the monitoring area on the basis of a detected edge hit, an edge hit meaning that the transmitted light is incident with a respective partial cross section on object surfaces at different distances.
An in vitro method of producing Neural Stem Cells, comprising: a) providing mammalian somatic cells selected from the group of fibroblasts, keratinocytes and adipocytes; and b) reprogramming said somatic cells to NSCs by introducing into the somatic cells at least two genes selected from the group of Bmi1 and Sox2 and culturing the somatic cells in a medium comprising growth factors selected from the group of FGF2, EGF and BDNF and a small molecule ROCK inhibitor. a) providing mammalian somatic cells selected from the group of fibroblasts, keratinocytes and adipocytes; and b) reprogramming said somatic cells to NSCs by introducing into the somatic cells at least two genes selected from the group of Bmi1 and Sox2 and culturing the somatic cells in a medium comprising growth factors selected from the group of FGF2, EGF and BDNF and a small molecule ROCK inhibitor.
A trip unit for a circuit breaker, said trip unit including a plurality of capabilities defining one trip unit style selected from a plurality of different trip unit styles, said trip unit comprising: a processor comprising a communication interface (52,54) including a communication protocol; and a communication adapter module comprising a first communication interface including said communication protocol, and a second communication interface, characterized in that said communication adapter module is structured to learn the plurality of capabilities of said trip unit from said processor employing said communication protocol, and to communicate with any of said plurality of different trip unit styles including said one trip unit style. a processor comprising a communication interface (52,54) including a communication protocol; and a communication adapter module comprising a first communication interface including said communication protocol, and a second communication interface, characterized in that said communication adapter module is structured to learn the plurality of capabilities of said trip unit from said processor employing said communication protocol, and to communicate with any of said plurality of different trip unit styles including said one trip unit style.
An image sensor, comprising: a light sensing array comprising a plurality of light sensing units, wherein each of the light sensing units comprises a plurality of light sensing pixels; a light filtering array disposed on the light sensing array, wherein the light filtering array comprises a plurality of light filtering units, each of the light filtering units correspondingly covers one of the light sensing units, and the light sensing pixels of each light sensing unit are adjacent light sensing pixels and correspond to the same light filtering unit; and a plurality of conversion units, wherein each of the conversion units comprises at least two parallel single stage source followers, and at least one of the at least two parallel single stage source followers is connected to a plurality of the light sensing pixels of a single light sensing unit, collects photoinduced charges of said plurality of light sensing pixels and converts said photoinduced charges into analog signals, characterized in that the light sensing pixels of each light sensing unit receive the same color of light. a light sensing array comprising a plurality of light sensing units, wherein each of the light sensing units comprises a plurality of light sensing pixels; a light filtering array disposed on the light sensing array, wherein the light filtering array comprises a plurality of light filtering units, each of the light filtering units correspondingly covers one of the light sensing units, and the light sensing pixels of each light sensing unit are adjacent light sensing pixels and correspond to the same light filtering unit; and a plurality of conversion units, wherein each of the conversion units comprises at least two parallel single stage source followers, and at least one of the at least two parallel single stage source followers is connected to a plurality of the light sensing pixels of a single light sensing unit, collects photoinduced charges of said plurality of light sensing pixels and converts said photoinduced charges into analog signals, characterized in that the light sensing pixels of each light sensing unit receive the same color of light.
Microvalve with a valve ball and a valve seat made of a hard material pairing of precious stones of a nozzle, wherein the valve seat comprises a sealing area and an outlet area and guide means (4, 40), comprising a guide area and a guide element, are arranged on the valve seat, wherein the guide area forms an upper release to the valve ball and the sealing area when the microvalve is closed, the guide area forms a flat transition angle to the sealing area, the transition angle between the sealing area and guide area is a maximum of 10°, preferably < 7°, particularly preferably 4°, the guide area comprises a concave area, characterised in that the guide element is designed in one piece, has a lower circular cylindrical receiving area for the valve seat and an upper guide area for guiding the valve ball and the guide area has at least three inwardly projecting guide webs and fluid channels defined by these.
Adjustable lens mount for a strip lens, having a support strip which, by means of one of its longitudinal sides, is connected to an optically non-active longitudinal side (5.1) of a strip lens to be mounted and a mounting plate which, with the ends thereof, is arranged at a fixed adjustment spacing (a) from the ends of the support strip and affixed to the latter by locking screws and which, between the ends, is connected to the support strip by first set screws (4.1), acting as tension screws, and second set screws (4.2), acting as pressure screws, which are arranged alternately in a row, such that the support strip and, as a result, the strip lens can be deformed over its length in the action direction of the first and second set screws (4.1) and (4.2), perpendicular to its optical axis (5.2), characterized in that the strip lens and the support strip are interconnected indirectly via a spacer strip, wherein one longitudinal side (7.1) of the spacer strip is cohesively connected to the longitudinal side of the strip lens (5.1) and the opposite longitudinal side (7.2) of said spacer strip is fixedly connected to the longitudinal side of the support strip and the spacer strip has a multiplicity of slits which are open to the opposite longitudinal side (7.2) and which extend in the action direction of the set screws (4.1, 4.2) over the whole width of the spacer strip (b A), as a result of which the dependence of the flexural strength of the spacer strip is determined by the geometry thereof, by the remaining residual thickness (d Ar) of the slit base remaining below the slits.
A flame retardant dispersion which comprises, as flame retardant component A, from 1 to 90% by weight of phosphinic salt of the formula, and/or a diphosphinic salt of the formula, and/or polymers of these, where R 1 and R 2 are identical or different and are methyl, ethyl, n-propyl, isopropyl, n-butyl, tert-butyl, n-pentyl, and/or phenyl, R 3 is C 1 -C 10 -alkylene, linear or branched, C 6 -C 10 -arylene, -alkylarylene, or -arylalkylene; M is Mg, Ca, Al, Sb, Sn, Ge, Ti, Zn, Fe, Zr, Ce, Bi, Sr, Mn, Li, Na and/or K; m is from 1 to 4; n is from 1 to 4; x is from 1 to 4, and comprises, as component B, from 0 to 75% by weight of a nitrogen-containing synergist or of a phosphorus/nitrogen flame retardant, and comprises, as component C, from 10 to 90% by weight of a liquid component which comprises acetone, methyl ethyl ketone, alcohols, water, benzene, toluene, xylenes, esters, dimethylformamide, alkyl glycols, propylene glycol methyl ether acetate, diethylene glycol ethyl ether acetate, polyethylene glycol dimethyl ether, ethyl acetate, butyl acetate, dioxane, tetrahydrofuran, diethyl ether, dimethyl ether, methyl tert-butyl ether, alkanes, cycloalkanes, N-methylpyrrolidone, acetic acid, acetic anhydride, formic acid, propionic acid, petroleum spirit, amyl acetate, pyridine, carbon disulfide, dimethyl sulfoxide, dichloromethane, trichloromethane, carbon tetrachloride, nitromethane, N-dimethylacetamide, and/or nitrobenzene. R 1 and R 2 are identical or different and are methyl, ethyl, n-propyl, isopropyl, n-butyl, tert-butyl, n-pentyl, and/or phenyl, R 3 is C 1 -C 10 -alkylene, linear or branched, C 6 -C 10 -arylene, -alkylarylene, or -arylalkylene; M is Mg, Ca, Al, Sb, Sn, Ge, Ti, Zn, Fe, Zr, Ce, Bi, Sr, Mn, Li, Na and/or K; m is from 1 to 4; n is from 1 to 4; x is from 1 to 4, R 3 is C 1 -C 10 -alkylene, linear or branched, C 6 -C 10 -arylene, -alkylarylene, or -arylalkylene; M is Mg, Ca, Al, Sb, Sn, Ge, Ti, Zn, Fe, Zr, Ce, Bi, Sr, Mn, Li, Na and/or K; m is from 1 to 4; n is from 1 to 4; x is from 1 to 4, and comprises, as component B, from 0 to 75% by weight of a nitrogen-containing synergist or of a phosphorus/nitrogen flame retardant, and comprises, as component C, from 10 to 90% by weight of a liquid component which comprises acetone, methyl ethyl ketone, alcohols, water, benzene, toluene, xylenes, esters, dimethylformamide, alkyl glycols, propylene glycol methyl ether acetate, diethylene glycol ethyl ether acetate, polyethylene glycol dimethyl ether, ethyl acetate, butyl acetate, dioxane, tetrahydrofuran, diethyl ether, dimethyl ether, methyl tert-butyl ether, alkanes, cycloalkanes, N-methylpyrrolidone, acetic acid, acetic anhydride, formic acid, propionic acid, petroleum spirit, amyl acetate, pyridine, carbon disulfide, dimethyl sulfoxide, dichloromethane, trichloromethane, carbon tetrachloride, nitromethane, N-dimethylacetamide, and/or nitrobenzene.
A method, comprising: receiving, by a wireless communication device (104, 204, 305), an indication of a plurality of transmission configuration indicator, TCI, states, from a wireless communication node (102, 202, 310); acquiring, by the wireless communication device (104, 204, 305), all configured quasi co-located, QCL, information of a first set of TCI states from the plurality of TCI states; and acquiring, by the wireless communication device (104, 204, 305), a partial portion of configured QCL information of a second set of TCI states from the plurality of TCI states, when a transmission scheme is configured for single frequency network, SFN, wherein the partial portion comprises one or more remaining QCL parameters after removing {Doppler Shift, Doppler Spread} from all configured QCL parameters in each TCI state of the second set of TCI states. receiving, by a wireless communication device (104, 204, 305), an indication of a plurality of transmission configuration indicator, TCI, states, from a wireless communication node (102, 202, 310); acquiring, by the wireless communication device (104, 204, 305), all configured quasi co-located, QCL, information of a first set of TCI states from the plurality of TCI states; and acquiring, by the wireless communication device (104, 204, 305), a partial portion of configured QCL information of a second set of TCI states from the plurality of TCI states, when a transmission scheme is configured for single frequency network, SFN, wherein the partial portion comprises one or more remaining QCL parameters after removing {Doppler Shift, Doppler Spread} from all configured QCL parameters in each TCI state of the second set of TCI states.