mhurhangee/ep-ind-claims huggingface dataset:
A compound of formula I where: R 1 is CONR 5 R 6; R 2 is or R 3 is hydrogen, halo, alkyl, alkenyl, hydroxy, benzyloxy, alkoxy, or haloalkoxy; R 4 is cycloalkyl; R 5 is alkenylSO 2, alkynylSO 2, alkoxyalkylSO 2, (cycloalkyl)alkylSO 2, (alkyl)cycloalkylSO 2, ((cycloalkyl)alkyl)cycloalkylSO 2, (benzyl)cycloalkylSO 2, (alkenyl)cycloalkylSO 2, (alkynyl)cycloalkylSO 2, (trialkylsilyl)cycloalkylSO 2, (CO 2 R 7)cycloalkylSO 2, (PhCO)cycloalkylSO 2, (PhN(R 7)CO)cycloalkylSO 2, tetrahydrofuranylSO 2, tetrahydropyranylSO 2, (tetrahydrofuranyl)alkylSO 2, (tetrahydropyranyl)alkylSO 2, isoxazolidinylSO 2, Ar 1 SO 2, (Ar 1)alkylSO 2, Ar 2 SO 2, or (CON(R 7)(R 7))alkyl; R 6 is hydrogen or alkyl; R 7 is hydrogen or alkyl; R 8 is hydrogen, alkyl, cycloalkyl, (cycloalkyl)alkyl, alkylcarbonyl, cycloalkylcarbonyl, haloalkylcarbonyl, alkoxycarbonyl, alkylSO 2, cycloalkylSO 2, haloalkylSO 2, aminocarbonyl, (alkylamino)carbonyl, (dialkylamino)carbonyl, benzyl, benzyloxycarbonyl, or pyridinyl; Ar 1 is phenyl, pyridinyl, pyrimidinyl, quinolinyl, or isoquinolinyl, and is substituted with 0-3 substituents selected from halo, alkyl, alkoxy, and cyano; and Ar 2 is furanyl, thienyl, pyrrolyl, isoxazolyl, isothiazolyl, pyrazolyl, oxazolyl, thiazolyl, imidazolyl, oxadiazolyl, thiadiazolyl, triazolyl, or tetrazolyl, and is substituted with 0-3 substituents selected from halo, alkyl, alkoxy, and cyano; or a pharmaceutically acceptable salt thereof. R 1 is CONR 5 R 6; R 2 is or R 3 is hydrogen, halo, alkyl, alkenyl, hydroxy, benzyloxy, alkoxy, or haloalkoxy; R 4 is cycloalkyl; R 5 is alkenylSO 2, alkynylSO 2, alkoxyalkylSO 2, (cycloalkyl)alkylSO 2, (alkyl)cycloalkylSO 2, ((cycloalkyl)alkyl)cycloalkylSO 2, (benzyl)cycloalkylSO 2, (alkenyl)cycloalkylSO 2, (alkynyl)cycloalkylSO 2, (trialkylsilyl)cycloalkylSO 2, (CO 2 R 7)cycloalkylSO 2, (PhCO)cycloalkylSO 2, (PhN(R 7)CO)cycloalkylSO 2, tetrahydrofuranylSO 2, tetrahydropyranylSO 2, (tetrahydrofuranyl)alkylSO 2, (tetrahydropyranyl)alkylSO 2, isoxazolidinylSO 2, Ar 1 SO 2, (Ar 1)alkylSO 2, Ar 2 SO 2, or (CON(R 7)(R 7))alkyl; R 6 is hydrogen or alkyl; R 7 is hydrogen or alkyl; R 8 is hydrogen, alkyl, cycloalkyl, (cycloalkyl)alkyl, alkylcarbonyl, cycloalkylcarbonyl, haloalkylcarbonyl, alkoxycarbonyl, alkylSO 2, cycloalkylSO 2, haloalkylSO 2, aminocarbonyl, (alkylamino)carbonyl, (dialkylamino)carbonyl, benzyl, benzyloxycarbonyl, or pyridinyl; Ar 1 is phenyl, pyridinyl, pyrimidinyl, quinolinyl, or isoquinolinyl, and is substituted with 0-3 substituents selected from halo, alkyl, alkoxy, and cyano; and Ar 2 is furanyl, thienyl, pyrrolyl, isoxazolyl, isothiazolyl, pyrazolyl, oxazolyl, thiazolyl, imidazolyl, oxadiazolyl, thiadiazolyl, triazolyl, or tetrazolyl, and is substituted with 0-3 substituents selected from halo, alkyl, alkoxy, and cyano; or a pharmaceutically acceptable salt thereof.
A combination of a tubular member of a biopsy device and a device for delivery of one or more marker bodies through the tubular member, the device for delivery of one or more marker bodies comprising: an elongated shaft having an inner lumen and a discharge opening in a distal portion of the elongated shaft; at least one marker body which is disposed within the inner lumen of the elongated shaft; a pusher element which is slidably disposed within the delivery device and which is configured to urge at least one marker body out the discharge opening in the distal portion of the elongated shaft; the tubular member being in the form of a disposable elongated probe component comprising a distal shaft portion with a penetrating distal tip, a tubular section (14, 15) proximal to the distal tip, an inner lumen extending within the tubular section and an open, tissue receiving aperture in the tubular section which provides access to tissue at the targeted site, a proximal extremity configured to be secured to a driver unit, and an elongated tissue cutting member which is disposed within the tubular section, which has at least one tissue cutting edge and which has an inner lumen extending therein, characterised by a slidably mounted, distally flared guide member which is disposed on the elongated shaft and which is configured to guide the distal portion of the elongated shaft into a proximal end of the tubular member of the biopsy device. an elongated shaft having an inner lumen and a discharge opening in a distal portion of the elongated shaft; at least one marker body which is disposed within the inner lumen of the elongated shaft; a pusher element which is slidably disposed within the delivery device and which is configured to urge at least one marker body out the discharge opening in the distal portion of the elongated shaft; the tubular member being in the form of a disposable elongated probe component comprising a distal shaft portion with a penetrating distal tip, a tubular section (14, 15) proximal to the distal tip, an inner lumen extending within the tubular section and an open, tissue receiving aperture in the tubular section which provides access to tissue at the targeted site, a proximal extremity configured to be secured to a driver unit, and an elongated tissue cutting member which is disposed within the tubular section, which has at least one tissue cutting edge and which has an inner lumen extending therein, a distal shaft portion with a penetrating distal tip, a tubular section (14, 15) proximal to the distal tip, an inner lumen extending within the tubular section and an open, tissue receiving aperture in the tubular section which provides access to tissue at the targeted site, a proximal extremity configured to be secured to a driver unit, and an elongated tissue cutting member which is disposed within the tubular section, which has at least one tissue cutting edge and which has an inner lumen extending therein,
A non-therapeutic cosmetic method of whitening skin or evening out skin tone, comprising topically applying to skin in need of treatment a composition comprising dried navy (haricot)-bean powder or an aqueous extract thereof, wherein topical application of the composition reduces melanogenesis and tyrosinase activity in skin and whitens skin or evens out skin tone.
A circuit (500, 611) configured to generate a delay comprising: a) a delay element having an input terminal and an output terminal, the delay element comprising one or more inverters; b) a capacitor having a first terminal receiving an input and a second terminal coupled to said input of said delay element; and c) a thin-film field-effect transistor, TFT, having a first source/drain terminal receiving a DC supply voltage, a second source/drain terminal coupled to said input of said delay element, and a gate electrically connected to said second source/drain terminal, the TFT being configured to provide a current and/or voltage to said capacitor, wherein said current and/or voltage has a value that falls within the tolerances of the manufacturing process utilized in making said TFT. a) a delay element having an input terminal and an output terminal, the delay element comprising one or more inverters; b) a capacitor having a first terminal receiving an input and a second terminal coupled to said input of said delay element; and c) a thin-film field-effect transistor, TFT, having a first source/drain terminal receiving a DC supply voltage, a second source/drain terminal coupled to said input of said delay element, and a gate electrically connected to said second source/drain terminal, the TFT being configured to provide a current and/or voltage to said capacitor,
A femoral implant for implantation on resected distal portions of patient's femur, comprising: an anterior portion comprising an anterior medial articulating surface, an anterior lateral articulating surface, an anterior patellofemoral channel and an anterior inner surface for corresponding to an anterior resection on the femur; a transition portion comprising a transition medial articulating surface, a transition patellofemoral channel, a transition lateral articulating surface, and a transition inner surface for corresponding to a transition resection on the femur, the transition inner surface intersecting the transition lateral articulating surface to form a truncation of the transition lateral articulating surface; a distal medial portion comprising a distal articulating surface and a distal inner surface for corresponding to a distal resection on the femur; and a posterior medial portion comprising a posterior medial articulating surface and at least one posterior medial inner surface for corresponding to at least one posterior resection of the femur, characterized in that planes of the anterior inner surface, the distal inner surface and the transition inner surface intersect at an implant point. an anterior portion comprising an anterior medial articulating surface, an anterior lateral articulating surface, an anterior patellofemoral channel and an anterior inner surface for corresponding to an anterior resection on the femur; a transition portion comprising a transition medial articulating surface, a transition patellofemoral channel, a transition lateral articulating surface, and a transition inner surface for corresponding to a transition resection on the femur, the transition inner surface intersecting the transition lateral articulating surface to form a truncation of the transition lateral articulating surface; a distal medial portion comprising a distal articulating surface and a distal inner surface for corresponding to a distal resection on the femur; and a posterior medial portion comprising a posterior medial articulating surface and at least one posterior medial inner surface for corresponding to at least one posterior resection of the femur,
Method for producing weaving reeds in which method strip-shaped or tape-shaped objects for forming the dents of the weaving reed are joined at a specific spacing in the width direction of the weaving reed, characterized in that - at least one of the strip-shaped or tape-shaped objects on that end face thereof that faces the width direction of the weaving reed, in particular in the end regions of said end face, is provided with an application of a pre-defined quantity (10 - 18) of at least one viscous substance, in order for the specific spacing to be exactly set; and - then is joined to the next strip-shaped or tape-shaped object. - at least one of the strip-shaped or tape-shaped objects on that end face thereof that faces the width direction of the weaving reed, in particular in the end regions of said end face, is provided with an application of a pre-defined quantity (10 - 18) of at least one viscous substance, in order for the specific spacing to be exactly set; and - then is joined to the next strip-shaped or tape-shaped object.
Endoscope comprising: an endoscope handle or interface; and an insertion cord configured to be inserted into a patient's body cavity and comprising an actively bendable bending section; the bending section comprising a plurality of bending segments including a proximal end segment, a plurality of intermediate segments and a distal end segment; the plurality of intermediate segments being separate annular or tubular segments made from a polymer material and having an outer circumferential side or surface and an inner circumferential side or surface; the plurality of intermediate segments comprising a plurality of first intermediate segments and a plurality of second intermediate segments being arranged alternately one after the other in a proximal-distal direction; wherein hinges between the first intermediate segments and the second intermediate segments are formed by hinge protrusions engaging in hinge recesses; wherein steering wires run on the inner circumferential side or surface of the first intermediate segments and on the outer circumferential side or surface in axially extending grooves of the second intermediate segments and keep the alternately arranged first intermediate segments and second intermediate segments together; and wherein the first intermediate segments comprise stabilizing protrusions arranged and accommodated in the axially extending grooves of the second intermediate segments, in which the steering wires run. an endoscope handle or interface; and an insertion cord configured to be inserted into a patient's body cavity and comprising an actively bendable bending section; the bending section comprising a plurality of bending segments including a proximal end segment, a plurality of intermediate segments and a distal end segment; the plurality of intermediate segments being separate annular or tubular segments made from a polymer material and having an outer circumferential side or surface and an inner circumferential side or surface; the plurality of intermediate segments comprising a plurality of first intermediate segments and a plurality of second intermediate segments being arranged alternately one after the other in a proximal-distal direction; wherein hinges between the first intermediate segments and the second intermediate segments are formed by hinge protrusions engaging in hinge recesses; wherein steering wires run on the inner circumferential side or surface of the first intermediate segments and on the outer circumferential side or surface in axially extending grooves of the second intermediate segments and keep the alternately arranged first intermediate segments and second intermediate segments together; and wherein the first intermediate segments comprise stabilizing protrusions arranged and accommodated in the axially extending grooves of the second intermediate segments, in which the steering wires run.
A method of manufacturing an aggregated precursor for manufacturing a light absorption layer, the method comprising: preparing a first solution comprising a sulfur and/or selenium compound, a second solution comprising an indium salt or indium salt and gallium salt, and a third solution comprising a copper salt; mixing and reacting the first solution and the second solution to synthesize indium and/or gallium containing chalcogenide particles; and mixing the third solution with the solution comprising the indium and/or gallium containing chalcogenide particles of the mixing and reacting to synthesize and purify an aggregated precursor for manufacturing a light absorption layer comprising a first phase comprising copper containing chalcogenide and a second phase comprising the indium and/or gallium containing chalcogenide, wherein, when the indium and/or gallium containing chalcogenide particles of the mixing are mixed with the third solution, a fourth solution comprising a sulfur and/or selenium compound is mixed together. preparing a first solution comprising a sulfur and/or selenium compound, a second solution comprising an indium salt or indium salt and gallium salt, and a third solution comprising a copper salt; mixing and reacting the first solution and the second solution to synthesize indium and/or gallium containing chalcogenide particles; and mixing the third solution with the solution comprising the indium and/or gallium containing chalcogenide particles of the mixing and reacting to synthesize and purify an aggregated precursor for manufacturing a light absorption layer comprising a first phase comprising copper containing chalcogenide and a second phase comprising the indium and/or gallium containing chalcogenide, wherein, when the indium and/or gallium containing chalcogenide particles of the mixing are mixed with the third solution, a fourth solution comprising a sulfur and/or selenium compound is mixed together.
A food-portioning device, comprising: an annular wall; a hub; and a plurality of dividing means extending from the hub to the annular wall so as to form a plurality of three-dimensional spaces between the dividing means, wherein the annular wall defines a peripheral boundary which, in cooperation with the plurality of dividing means, defines the plurality of three-dimensional spaces for defining food portion sizes; each space having an open top and an open bottom; at least one of the dividing means is attached to the hub and/or to the annular wall in a manner that does not allow that dividing means to rotate about the hub thereby defining a non-rotatable dividing means, characterised in that all other dividing means are attached to the hub in a manner that allows them to at least partially rotate about the hub relative to the non-rotatable dividing means and relative to an adjacent dividing means. an annular wall; a hub; and a plurality of dividing means extending from the hub to the annular wall so as to form a plurality of three-dimensional spaces between the dividing means, wherein the annular wall defines a peripheral boundary which, in cooperation with the plurality of dividing means, defines the plurality of three-dimensional spaces for defining food portion sizes; each space having an open top and an open bottom; at least one of the dividing means is attached to the hub and/or to the annular wall in a manner that does not allow that dividing means to rotate about the hub thereby defining a non-rotatable dividing means, characterised in that all other dividing means are attached to the hub in a manner that allows them to at least partially rotate about the hub relative to the non-rotatable dividing means and relative to an adjacent dividing means.
A semiconductor light emitting device comprising: a substrate of alumina or aluminium nitride, the substrate having a face; a flexible film that includes therein an optical element, wherein the flexible film is silicone-based and conforms to the substrate face as it expands and contracts during operation; and a semiconductor light emitting diode between the substrate and the flexible film and configured to emit light through the optical element, wherein the optical element comprises a lens. a substrate of alumina or aluminium nitride, the substrate having a face; a flexible film that includes therein an optical element, wherein the flexible film is silicone-based and conforms to the substrate face as it expands and contracts during operation; and a semiconductor light emitting diode between the substrate and the flexible film and configured to emit light through the optical element, wherein the optical element comprises a lens.
Rubber compound for the preparation of portions of pneumatic tyres comprising a cross-linking unsaturated chain polymer base, a filler system and a vulcanizing system; said compound being characterized in that said filler system comprises (a) a first carbon black having a surface area less than or equal to 170 m 2 /gr in a quantity greater than or equal to 25 phr; (b) a second carbon black having a surface area greater than or equal to 250 m 2 /gr in a quantity such that the ratio between the quantity of said first carbon black and the quantity of said second carbon black is greater than or equal to 3 and less than or equal to 10; (c) a carbon black dispersing agent in a quantity of less than or equal to 1 phr.
A method of printing on a security document substrate, comprising: using a print mechanism to print on a first surface of the security document substrate using a section of a print ribbon; flipping the security document substrate over so that a second surface thereof is available for printing using the print mechanism; using the print mechanism to print on the second surface of the security document substrate using the section of the print ribbon that was used to print on the first surface, wherein the printing on the first surface does not overlap the printing on the second surface. using a print mechanism to print on a first surface of the security document substrate using a section of a print ribbon; flipping the security document substrate over so that a second surface thereof is available for printing using the print mechanism; using the print mechanism to print on the second surface of the security document substrate using the section of the print ribbon that was used to print on the first surface, wherein the printing on the first surface does not overlap the printing on the second surface.
A vehicle tire having at least one carcass ply extending between bead portions, a tread portion, and a belt arrangement located between the carcass and the tread portion, wherein fillers (10, 11) of different heights are arranged in the bead portions on the inward-facing side of the tire and on the outward-facing side of the tire; and wherein the filler located on the inward-facing side of the tire has a smaller height than the filler located on the outward-facing side of the tire, characterized in that the tread portion consists of at least two compound components (2, 3) which are different and are mutually distinguishable in a predeterminable manner.
A fluorescent label comprising a fluorescent dye-containing nanoparticle, characterized in that a parent material of the fluorescent dye-containing nanoparticle is a melamine resin or a styrene resin, and the fluorescent dye is a perylene derivative with a sulfonic acid group, a sulforhodamine 101 or sulforhodamine 101 acid chloride, and the fluorescent dye is adsorbed to the parent material of the nanoparticle.
A system comprising: a cleaning cartridge and an apparatus for the heat treatment or cooking of substances, said apparatus including a cavity, said cavity having a bottom and a drain disposed in said bottom, said drain having an opening leading to a cleaning box, said drain and said cleaning box allowing for the ingress and egress of water for cleaning the apparatus, characterized in that: said cartridge contains at least one cleaning agent and at least one rinsing agent and has a water soluble or heat sensitive seal to prevent premature release of the cleaning agent and the rinsing agent from the cartridge; and the system comprises a mechanism for opening the cleaning cartridge inside the apparatus, wherein said mechanism comprises (a) a neck portion having a periphery sized to fit into the opening of said drain, (b) a flange portion disposed about the neck portion, the flange portion having a periphery sized larger than the opening of said drain, (c) a plurality of apertures disposed above the neck portion within the periphery of the flange portion, and (d) at least one protruding edge, the at least one protruding edge proximal at least one of the plurality of apertures disposed in a direction away from said drain and toward said cavity, wherein the protruding edge on the mechanism is configured to pierce the seal so that the cleaning and rinsing agent is dispensed into the apparatus. said cartridge contains at least one cleaning agent and at least one rinsing agent and has a water soluble or heat sensitive seal to prevent premature release of the cleaning agent and the rinsing agent from the cartridge; and the system comprises a mechanism for opening the cleaning cartridge inside the apparatus, wherein said mechanism comprises (a) a neck portion having a periphery sized to fit into the opening of said drain, (b) a flange portion disposed about the neck portion, the flange portion having a periphery sized larger than the opening of said drain, (c) a plurality of apertures disposed above the neck portion within the periphery of the flange portion, and (d) at least one protruding edge, the at least one protruding edge proximal at least one of the plurality of apertures disposed in a direction away from said drain and toward said cavity, wherein the protruding edge on the mechanism is configured to pierce the seal so that the cleaning and rinsing agent is dispensed into the apparatus. (a) a neck portion having a periphery sized to fit into the opening of said drain, (b) a flange portion disposed about the neck portion, the flange portion having a periphery sized larger than the opening of said drain, (c) a plurality of apertures disposed above the neck portion within the periphery of the flange portion, and (d) at least one protruding edge, the at least one protruding edge proximal at least one of the plurality of apertures disposed in a direction away from said drain and toward said cavity, wherein the protruding edge on the mechanism is configured to pierce the seal so that the cleaning and rinsing agent is dispensed into the apparatus.