mhurhangee/ep-ind-claims huggingface dataset:
A sterile transfer device for fluids in the form of a connector or valve for use in the pharmaceutical and biopharmaceutical industry, comprising: a body having a bore formed through at least a portion of its interior, the body having a first end containing a face designed to be attached to an upstream component (54;72); a plunger (18;70;108) contained within the bore, said plunger having a first end and being movable within the bore, wherein said first end of said plunger (18;70;108), when in a closed position, is in alignment with said face of said first end of said body, which combined form a surface (46;104) capable of withstanding steam sterilization and a sterile barrier against the environment to the rest of the interior of said body and said plunger (18;70;108), and wherein, when in an open position, said plunger (18;70;108) allows passage of fluid from said first end of said body to a fluid channel (27;185) that forms a fluid connection to a downstream component or tubing; at least two seals arranged along the length of the plunger (18;70;108) to, respectively, form a fluid tight seal at the first end in the closed position and between various portions of the plunger (18;70;108) and the bore when in the closed and open positions; a cam slot formed in the body; and a cam provided on said plunger (18;70;108), wherein said cam rides in said cam slot such that a rearward and forward movement between the open position and the closed position and a rotation of said plunger (18;70;108) within said bore is defined. a body having a bore formed through at least a portion of its interior, the body having a first end containing a face designed to be attached to an upstream component (54;72); a plunger (18;70;108) contained within the bore, said plunger having a first end and being movable within the bore, wherein said first end of said plunger (18;70;108), when in a closed position, is in alignment with said face of said first end of said body, which combined form a surface (46;104) capable of withstanding steam sterilization and a sterile barrier against the environment to the rest of the interior of said body and said plunger (18;70;108), and wherein, when in an open position, said plunger (18;70;108) allows passage of fluid from said first end of said body to a fluid channel (27;185) that forms a fluid connection to a downstream component or tubing; at least two seals arranged along the length of the plunger (18;70;108) to, respectively, form a fluid tight seal at the first end in the closed position and between various portions of the plunger (18;70;108) and the bore when in the closed and open positions; a cam slot formed in the body; and a cam provided on said plunger (18;70;108), wherein said cam rides in said cam slot such that a rearward and forward movement between the open position and the closed position and a rotation of said plunger (18;70;108) within said bore is defined.
A binding molecule capable of binding L1, (a) being selected from the group consisting of single chain antibodies, scFv, multimers ofscFv like diabodies, triabodies or tetrabodies, antibody fragments, Fab, tandabs, flexibodies, bispecific antibodies, and chimeric antibodies, and/or (b) which comprises at least one Ig domain, and wherein the binding molecule capable of binding L1: (i) is characterized in that its complementarity determining regions (CDRs) have the following sequences: LCDR1: RASQDISNYLN (SEQ ID No.: 24), LCDR2: YTSRLHS (SEQ ID No.: 25), LCDR3: QQGNTLPWT (SEQ ID No.: 26), HCDR1: RYWML (SEQ ID No.: 27), HCDR2: EINPRNDRTNYNEKFKT (SEQ ID No.: 28), and HCDR3: GGGYAMDY (SEQ ID No.: 29), and which binding molecule binds L1 with an affinity of at least 10 -10 M, or (ii) is characterized in that its complementarity determining regions (CDRs) have the following sequences: LCDR1: QDISNY (SEQ ID No.: 30), LCDR2: YTS, LCDR3: QQGNTLPWT (SEQ ID No.: 31), HCDR1: GYTFTRYW (SEQ ID No.: 32), HCDR2: INPRNDRT (SEQ ID No.: 33), and HCDR3: ALGGGYAMDY (SEQ ID No.: 34), and which binding molecule binds L1 with an affinity of at least 10 -10 M. (a) being selected from the group consisting of single chain antibodies, scFv, multimers ofscFv like diabodies, triabodies or tetrabodies, antibody fragments, Fab, tandabs, flexibodies, bispecific antibodies, and chimeric antibodies, and/or (b) which comprises at least one Ig domain, and wherein the binding molecule capable of binding L1: (i) is characterized in that its complementarity determining regions (CDRs) have the following sequences: LCDR1: RASQDISNYLN (SEQ ID No.: 24), LCDR2: YTSRLHS (SEQ ID No.: 25), LCDR3: QQGNTLPWT (SEQ ID No.: 26), HCDR1: RYWML (SEQ ID No.: 27), HCDR2: EINPRNDRTNYNEKFKT (SEQ ID No.: 28), and HCDR3: GGGYAMDY (SEQ ID No.: 29), and which binding molecule binds L1 with an affinity of at least 10 -10 M, or (ii) is characterized in that its complementarity determining regions (CDRs) have the following sequences: LCDR1: QDISNY (SEQ ID No.: 30), LCDR2: YTS, LCDR3: QQGNTLPWT (SEQ ID No.: 31), HCDR1: GYTFTRYW (SEQ ID No.: 32), HCDR2: INPRNDRT (SEQ ID No.: 33), and HCDR3: ALGGGYAMDY (SEQ ID No.: 34), and which binding molecule binds L1 with an affinity of at least 10 -10 M. (i) is characterized in that its complementarity determining regions (CDRs) have the following sequences: LCDR1: RASQDISNYLN (SEQ ID No.: 24), LCDR2: YTSRLHS (SEQ ID No.: 25), LCDR3: QQGNTLPWT (SEQ ID No.: 26), HCDR1: RYWML (SEQ ID No.: 27), HCDR2: EINPRNDRTNYNEKFKT (SEQ ID No.: 28), and HCDR3: GGGYAMDY (SEQ ID No.: 29), and which binding molecule binds L1 with an affinity of at least 10 -10 M, or (ii) is characterized in that its complementarity determining regions (CDRs) have the following sequences: LCDR1: QDISNY (SEQ ID No.: 30), LCDR2: YTS, LCDR3: QQGNTLPWT (SEQ ID No.: 31), HCDR1: GYTFTRYW (SEQ ID No.: 32), HCDR2: INPRNDRT (SEQ ID No.: 33), and HCDR3: ALGGGYAMDY (SEQ ID No.: 34), and which binding molecule binds L1 with an affinity of at least 10 -10 M.
A device for determining an adjustment for a suspension component (25, 80) of a vehicle, which device comprises: a display; a measuring sensor; a memory storing computer-executable instructions; and a processor, the arrangement being such that when executed by the processor, the computer-executable instructions cause the device to: receive a weight value that indicates a load to be carried by the vehicle, determine a target pressure for an air spring of the suspension component based on the weight value, measure a loaded position of the suspension component (25, 80) using the measuring sensor, and determine an adjustment to the suspension component based on the loaded position and the target pressure; characterized in that said measuring sensor comprises an image sensor and the computer-executable instructions are configured to measure the loaded position of the suspension component by using the image sensor to capture the position of an indicator member on the suspension component in an unloaded position in which the suspension component has returned to extension from a compressed position, the indicator member being movable as the suspension component is compressed under the weight of the user and which retains its position at the point at which the suspension component returns to extension thereby recording a maximum compression of the suspension component under the weight of the user(s) of the vehicle in a sag position after the suspension component has returned to extension. a display; a measuring sensor; a memory storing computer-executable instructions; and a processor, the arrangement being such that when executed by the processor, the computer-executable instructions cause the device to: receive a weight value that indicates a load to be carried by the vehicle, determine a target pressure for an air spring of the suspension component based on the weight value, measure a loaded position of the suspension component (25, 80) using the measuring sensor, and receive a weight value that indicates a load to be carried by the vehicle, determine a target pressure for an air spring of the suspension component based on the weight value, measure a loaded position of the suspension component (25, 80) using the measuring sensor, and determine an adjustment to the suspension component based on the loaded position and the target pressure; characterized in that said measuring sensor comprises an image sensor and the computer-executable instructions are configured to measure the loaded position of the suspension component by using the image sensor to capture the position of an indicator member on the suspension component in an unloaded position in which the suspension component has returned to extension from a compressed position, the indicator member being movable as the suspension component is compressed under the weight of the user and which retains its position at the point at which the suspension component returns to extension thereby recording a maximum compression of the suspension component under the weight of the user(s) of the vehicle in a sag position after the suspension component has returned to extension.
A conductive material dispersion containing a conductive material containing carbon fibers, a dispersant, and a dispersion medium, wherein the dispersant contains a copolymer A containing a nitrile group-containing structural unit and an aliphatic hydrocarbon structural unit, and a Mooney viscosity (ML 1+4, 100°C) of the copolymer A is 40 to 70, and a phase angle of the conductive material dispersion at a frequency of 1 Hz obtained by dynamic viscoelasticity measurement is 19° or greater, the Mooney viscosity and the phase angle being measured according to the description. the dispersant contains a copolymer A containing a nitrile group-containing structural unit and an aliphatic hydrocarbon structural unit, and a Mooney viscosity (ML 1+4, 100°C) of the copolymer A is 40 to 70, and a phase angle of the conductive material dispersion at a frequency of 1 Hz obtained by dynamic viscoelasticity measurement is 19° or greater, the Mooney viscosity and the phase angle being measured according to the description.
Dietary composition, for its use as an orally-administered dietary product for the reduction of visceral fat in an obese individual during the pre-operative phase of a bariatric surgery intervention, comprising a mixture of active ingredients consisting of at least: - A whey hydrolyzate with a molecular weight of between 200 and 10,000 daltons, - An isolate and/or a concentrate of whey, and - Calcium caseinate. - A whey hydrolyzate with a molecular weight of between 200 and 10,000 daltons, - An isolate and/or a concentrate of whey, and - Calcium caseinate.
A method of code-multiplexing a control signal onto a shared control channel comprising: repeating a control bit for a mobile station associated with the shared control channel in each slot of a predetermined time interval; spreading the control bit in each slot of the predetermined time interval at bit rate using a bit-level spreading sequence; varying the bit-level spreading sequence from slot to slot according to a predefined sequence-hopping pattern; and assigning a common channelization code to the shared control channel. repeating a control bit for a mobile station associated with the shared control channel in each slot of a predetermined time interval; spreading the control bit in each slot of the predetermined time interval at bit rate using a bit-level spreading sequence; varying the bit-level spreading sequence from slot to slot according to a predefined sequence-hopping pattern; and assigning a common channelization code to the shared control channel.
Process for preparing a carbon species partially or completely covered with silica, comprising the following steps: - the carbon species is brought into contact, in an aqueous medium, with one or more cationic surfactants, - the pH of the reaction medium of the suspension is adjusted using an alkaline agent to a pH that varies from 8 to 10, - one or more alkali metal silicates are added to the reaction medium obtained, while maintaining the pH of the reaction medium between 8 and 10. - the carbon species is brought into contact, in an aqueous medium, with one or more cationic surfactants, - the pH of the reaction medium of the suspension is adjusted using an alkaline agent to a pH that varies from 8 to 10, - one or more alkali metal silicates are added to the reaction medium obtained, while maintaining the pH of the reaction medium between 8 and 10.
A method of preparing a magnetic particle comprising a polymer matrix and at least one magnetic core, preferably at least two magnetic cores, wherein the polymer matrix comprises at least one hypercrosslinked polymer, wherein the method comprises: (i) providing at least one magnetic core, preferably at least two magnetic cores, (ii) providing polymer precursor molecules, (iii) polymerizing the polymer precursor molecules according to (ii) in the presence of the at least one magnetic core, thereby forming a particle comprising the at least one magnetic core, preferably the at least two magnetic cores, embedded in a polymer matrix, and (iv) hypercrosslinking the polymer matrix of the polymer particle obtained in (iii) via a Friedel-Crafts reaction, wherein the reaction is carried out at a temperature equal to or less than 80°C, to give the magnetic particle, wherein the magnetic particle has a particle size in the range of from 5 to 40 micrometers, wherein the reaction in (iv) is not carried out in a solvent comprising dichloroethane or other organic halides; wherein the reaction in (iv) is carried out for a reaction time of 2 h or less; wherein the reaction in (iv) is carried out in a solvent comprising at least THF, acetonitrile, DMF, dioxane or toluol; wherein the hypercrosslinking in (iv) is carried out in the presence of a catalyst selected from the group consisting of a Lewis acid. (i) providing at least one magnetic core, preferably at least two magnetic cores, (ii) providing polymer precursor molecules, (iii) polymerizing the polymer precursor molecules according to (ii) in the presence of the at least one magnetic core, thereby forming a particle comprising the at least one magnetic core, preferably the at least two magnetic cores, embedded in a polymer matrix, and (iv) hypercrosslinking the polymer matrix of the polymer particle obtained in (iii) via a Friedel-Crafts reaction, wherein the reaction is carried out at a temperature equal to or less than 80°C,
A method for predicting dietary weight loss in a subject comprising the steps of: (a) identifying an overweight or obese subject with at least one preferred gut microbiota characteristic (PGMC) selected from: (i) subjects with a relative abundance of log10( Prevotella spp.) of greater than -3 in their microbiota; (ii) subjects with a relative abundance of log10( Prevotella spp. / Bacteriodes spp.) of greater than -2 in their microbiota; (iii) subjects with a relative abundance of Log 10( Prevotella spp. / Bacteroidetes all) of greater than - 2 in their microbiota; and (iv) subjects with a relative abundance of Log 10( Bacteroidetes all/ Bacteroides spp.) of greater than 0 in their microbiota; wherein identifying a subject having at least one PGMC comprises testing a sample of gut microbiota from the subject to determine whether the subject has the at least one PGMC, optionally wherein the sample is a fecal sample; and (b) predicting dietary weight loss success of the subject having the at least one PGMC on a diet rich in fiber and wholegrains comprising from 30 to 55 g of fiber per day. (a) identifying an overweight or obese subject with at least one preferred gut microbiota characteristic (PGMC) selected from: (i) subjects with a relative abundance of log10( Prevotella spp.) of greater than -3 in their microbiota; (ii) subjects with a relative abundance of log10( Prevotella spp. / Bacteriodes spp.) of greater than -2 in their microbiota; (iii) subjects with a relative abundance of Log 10( Prevotella spp. / Bacteroidetes all) of greater than - 2 in their microbiota; and (iv) subjects with a relative abundance of Log 10( Bacteroidetes all/ Bacteroides spp.) of greater than 0 in their microbiota; wherein identifying a subject having at least one PGMC comprises testing a sample of gut microbiota from the subject to determine whether the subject has the at least one PGMC, optionally wherein the sample is a fecal sample; and (i) subjects with a relative abundance of log10( Prevotella spp.) of greater than -3 in their microbiota; (ii) subjects with a relative abundance of log10( Prevotella spp. / Bacteriodes spp.) of greater than -2 in their microbiota; (iii) subjects with a relative abundance of Log 10( Prevotella spp. / Bacteroidetes all) of greater than - 2 in their microbiota; and (iv) subjects with a relative abundance of Log 10( Bacteroidetes all/ Bacteroides spp.) of greater than 0 in their microbiota; (b) predicting dietary weight loss success of the subject having the at least one PGMC on a diet rich in fiber and wholegrains comprising from 30 to 55 g of fiber per day.
A device for grooving cardboard cuttings, featuring • a driven, horizontally supported transport drum, • several spaced-apart endless belts that revolve around rollers, wherein said endless belts are partially looped around the transport drum such that an inlet and an outlet are formed and effectively convey the cardboard cuttings by pressing said cardboard cuttings against the drum shell, and • at least one groove cutting tool that can be positioned between the belts on the circumference of the transport drum and features at least one knife that is fixed on a knife receptacle, characterized in that the knife receptacle can be adjusted by means of a curved guide provided in the groove cutting tool, wherein the center of curvature of the curved guide lies in the region of the drum shell, as well as in the region of a blade tip (71 a) of the at least one knife. • a driven, horizontally supported transport drum, • several spaced-apart endless belts that revolve around rollers, wherein said endless belts are partially looped around the transport drum such that an inlet and an outlet are formed and effectively convey the cardboard cuttings by pressing said cardboard cuttings against the drum shell, and • at least one groove cutting tool that can be positioned between the belts on the circumference of the transport drum and features at least one knife that is fixed on a knife receptacle,
Lid for a container, in particular for a beverage can, comprising: a lid panel having a break-open region which is at least partially surrounded by a predetermined breaking line, and having a fastening element which is arranged on the lid panel; a lever tab rotatably attached to the fastening element for breaking open the break-open region along the predetermined breaking line in the direction of an underside of the lid panel and thus providing a removal opening in the lid panel; wherein the lever tab comprises a closure element for sealingly closing the removal opening; and wherein the closure element comprises a first portion which can be applied to an upper side of the lid panel and partially sealingly enclosing the removal opening; characterized in that the closure element comprises a second portion which can be applied to an underside of the lid panel and partially sealingly enclosing the removal opening. a lid panel having a break-open region which is at least partially surrounded by a predetermined breaking line, and having a fastening element which is arranged on the lid panel; a lever tab rotatably attached to the fastening element for breaking open the break-open region along the predetermined breaking line in the direction of an underside of the lid panel and thus providing a removal opening in the lid panel; wherein the lever tab comprises a closure element for sealingly closing the removal opening; and wherein the closure element comprises a first portion which can be applied to an upper side of the lid panel and partially sealingly enclosing the removal opening; characterized in that the closure element comprises a second portion which can be applied to an underside of the lid panel and partially sealingly enclosing the removal opening.
A composition characterized by comprising 5 mass% to less than 100 mass% of a silanol compound represented by the Formula:; and more than 0 mass% and less than 95 mass% of at least one compound selected from the group consisting of an amine compound and an amide compound.
A coating composition comprising a stable aqueous dispersion of polymer particles and a phenyl glycidyl ether adduct of the compound of Formula I: where m is from 1 to 60.
Protection device against flames and/or explosions,. comprising an in-line protection device ( 805,905,1005) for the protection against the propagation of flames in presence of deflagrations or detonations, wherein the protection device comprises two flame arrester blocks ( 230-3, 230-4, 230-5, 230-6), wherein each one of said two flame arrester blocks ( 230-3, 230-4, 230-5, 230-6) comprises: - at least one first plate having an external perimeter and at least one aperture in a region inside said external perimeter, and - a second, closing plate stacked on said at least one first plate along a stacking direction and spaced apart from the at least one first plate so as to define, between said at least one first plate and said second plate a gap transversal to said packing direction, characterized in that said two flame arrester blocks ( 230-3, 230-4, 230-5, 230-6) are arranged one opposed to the other with facing second, closing plates ( 310-3, 310-4, 310, 310-5, 3106) and contained in a jacket ( 820, 920, 1020) for allowing a bidirectional flow of fluid and a bidirectional protection against propagation of flames. - at least one first plate having an external perimeter and at least one aperture in a region inside said external perimeter, and - a second, closing plate stacked on said at least one first plate along a stacking direction and spaced apart from the at least one first plate so as to define, between said at least one first plate and said second plate a gap transversal to said packing direction,
In combination, a printer having a top-feed roller accessible from outside the printer and a feed table positioned to hold a stack of sheets to be fed into the top-feed roller, and a feeder assembly comprising a bottom-feed sheet feeder physically and electrically separate from the printer, characterized in that the feeder assembly further comprises a delivery table positioned to receive sheets from the sheet feeder and deliver the sheets one at a time to the top-feed roller, the delivery table being pivotably mounted relative to the printer, to allow a free end of the delivery table to move vertically with respect to the top-feed roller, the delivery table being positioned on the feed table.
A handling and folding apparatus for a dividing element that is arrangeable within an outer packaging, wherein the dividing element is designed as a blank with at least one folding line (3, 4), the handling and folding apparatus comprising a magazine for dividing elements, at least one holding device for the dividing elements, a transport device for the outer packagings, and at least one contact surface (12, 13) for the dividing element, wherein the dividing element, when in contact with the at least one contact surface (12, 13) at least in some sections, is able to be folded over along the at least one folding line (3, 4), and is subsequently placeable into the outer packaging; wherein the at least one contact surface (12, 13) is assigned at least one guide element (15, 16) for guiding the dividing element, which has been folded along the at least one folding line (3, 4), while the dividing element is being placed into the outer packaging, wherein the at least one holding device is rotatable, wherein the contact of the dividing element with the at least one contact surface (12, 13) at least in some sections and a folding of the dividing element along the at least one folding line (3, 4) is producible by a rotation of the holding device, in particular, by approximately 90°.