A communication device (132, 208, 308, 500) for providing digital transport of signals in a distributed antenna system, the communication device (132, 208, 308, 500) comprising: a reception path circuit including an analog-to-digital converter and configured to output digitized radio frequency spectrum at an input sampling rate based on input signals of analog radio frequency spectrum from multiple non-adjacent spectral regions (451, 452) of the analog radio frequency spectrum; a logic device coupled to the reception path circuit, including a plurality of digital down converters (625, 626) operating in parallel and configured to receive the digitized radio frequency spectrum at the input sampling rate from the reception path circuit, the logic device further configured to produce a first plurality of sets of digitized baseband data samples at a plurality of sampling rates in parallel, each set of the first plurality of sets of digitized baseband data samples corresponding to a corresponding distinct one of the multiple non-adjacent spectral regions (451, 452) of the analog radio frequency spectrum; wherein each digital down converter (625, 626) of the plurality of digital down converters (625, 626) is configured to convert data corresponding to the corresponding distinct one of the multiple non-adjacent spectral regions (451, 452) of the analog radio frequency spectrum into a corresponding set of digitized baseband data samples at a corresponding sampling rate; wherein the logic device is further configured to multiplex the first plurality of sets of digitized baseband data samples into a serial data stream transport frame by assigning each of the first plurality of sets of digitized baseband data samples to a corresponding timeslot (461, 462, 463) of the serial data stream transport frame, wherein each set of the first plurality of sets of digitized baseband data samples has a corresponding sampling rate; and a transceiver (132, 208, 308) configured to transmit the serial data stream transport frame. a reception path circuit including an analog-to-digital converter and configured to output digitized radio frequency spectrum at an input sampling rate based on input signals of analog radio frequency spectrum from multiple non-adjacent spectral regions (451, 452) of the analog radio frequency spectrum; a logic device coupled to the reception path circuit, including a plurality of digital down converters (625, 626) operating in parallel and configured to receive the digitized radio frequency spectrum at the input sampling rate from the reception path circuit, the logic device further configured to produce a first plurality of sets of digitized baseband data samples at a plurality of sampling rates in parallel, each set of the first plurality of sets of digitized baseband data samples corresponding to a corresponding distinct one of the multiple non-adjacent spectral regions (451, 452) of the analog radio frequency spectrum; wherein each digital down converter (625, 626) of the plurality of digital down converters (625, 626) is configured to convert data corresponding to the corresponding distinct one of the multiple non-adjacent spectral regions (451, 452) of the analog radio frequency spectrum into a corresponding set of digitized baseband data samples at a corresponding sampling rate; wherein the logic device is further configured to multiplex the first plurality of sets of digitized baseband data samples into a serial data stream transport frame by assigning each of the first plurality of sets of digitized baseband data samples to a corresponding timeslot (461, 462, 463) of the serial data stream transport frame, wherein each set of the first plurality of sets of digitized baseband data samples has a corresponding sampling rate; and a transceiver (132, 208, 308) configured to transmit the serial data stream transport frame.