Medicament delivery device comprising - a generally elongated housing, having a proximal and a distal end, - a medicament delivery actuation mechanism, capable upon activation, of delivering doses of medicament from - a medicament container, arranged with a medicament delivery member and placed in said housing, - a medicament delivery member shield arranged to said medicament delivery member, - a medicament delivery member guard arranged movable in the proximal end of said housing, wherein said medicament delivery member guard is operably connected to said medicament delivery actuation mechanism, - a protective cap releasibly arranged to said proximal end of said housing, - said protective cap being provided with a medicament delivery member shield remover, a blocking element arranged to said medicament delivery member guard; - said blocking element is arranged movable between a blocking position and a release position, characterised in that the proximal end of the housing is arranged with an end cover as a housing part; said blocking element is arranged with an engagement surface arranged to engage with a proximal area of said housing end cover part, said proximal area stop surface comprises the proximal end surface of the housing part; said blocking element is arranged to engage with a surface of said medicament delivery member shield remover, retaining said blocking element in said blocking position, wherein engagement of said engagement surface with said proximal area causes a blocking of said medicament delivery member guard from movement, and wherein removal of said protective cap and said medicament delivery member shield remover enables a movement of said blocking element to a release position when said engagement surface engages said proximal area, allowing said medicament delivery member guard to move in the distal direction so as to cause an activation of the device for delivering a dose of medicament. - a generally elongated housing, having a proximal and a distal end, - a medicament delivery actuation mechanism, capable upon activation, of delivering doses of medicament from - a medicament container, arranged with a medicament delivery member and placed in said housing, - a medicament delivery member shield arranged to said medicament delivery member, - a medicament delivery member guard arranged movable in the proximal end of said housing, wherein said medicament delivery member guard is operably connected to said medicament delivery actuation mechanism, - a protective cap releasibly arranged to said proximal end of said housing, - said protective cap being provided with a medicament delivery member shield remover, a blocking element arranged to said medicament delivery member guard; - said blocking element is arranged movable between a blocking position and a release position, characterised in that the proximal end of the housing is arranged with an end cover as a housing part; said blocking element is arranged with an engagement surface arranged to engage with a proximal area of said housing end cover part, said proximal area stop surface comprises the proximal end surface of the housing part; said blocking element is arranged to engage with a surface of said medicament delivery member shield remover, retaining said blocking element in said blocking position, wherein engagement of said engagement surface with said proximal area causes a blocking of said medicament delivery member guard from movement, and