mhurhangee/ep-ind-claims huggingface dataset:
A compound having the formula: or a pharmaceutically acceptable salt thereof, wherein: A is C 3 -C 6 cycloalkyl, C 2 -C 4 alkenyl, C 3 -C 6 cycloalkenyl, 4- to 6-membered monocyclic heterocycloalkyl, 4- to 6-membered monocyclic heterocycloalkenyl, -C(=O)NR a R b, -C(=O)-(4- to 6-membered monocyclic heterocycloalkyl), -C(R c)=NOR d, or HetA, wherein cycloalkyl is optionally substituted by 1 or 2 substituents selected from C 1 -C 6 alkyl and halo, wherein HetA is optionally substituted by 1 or 2 ring substituents R 1, and wherein the 4- to 6-membered monocyclic heterocycloalkyl is optionally substituted with oxo; HetA is a 5- or 6- membered aromatic monocyclic ring with 1, 2 or 3 heteroatom ring atoms independently selected from N, O and S;R a, R b, R c, R d are independently selected from H and C 1 -C 6 alkyl, and; each occurrence of R 1 is independently selected from halo, -OH, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, -O-(C 1 -C 6 alkyl), -O-(C 1 -C 6 haloalkyl), oxo, cyano, and -O-phenyl-F. A is C 3 -C 6 cycloalkyl, C 2 -C 4 alkenyl, C 3 -C 6 cycloalkenyl, 4- to 6-membered monocyclic heterocycloalkyl, 4- to 6-membered monocyclic heterocycloalkenyl, -C(=O)NR a R b, -C(=O)-(4- to 6-membered monocyclic heterocycloalkyl), -C(R c)=NOR d, or HetA, wherein cycloalkyl is optionally substituted by 1 or 2 substituents selected from C 1 -C 6 alkyl and halo, wherein HetA is optionally substituted by 1 or 2 ring substituents R 1, and wherein the 4- to 6-membered monocyclic heterocycloalkyl is optionally substituted with oxo; HetA is a 5- or 6- membered aromatic monocyclic ring with 1, 2 or 3 heteroatom ring atoms independently selected from N, O and S;R a, R b, R c, R d are independently selected from H and C 1 -C 6 alkyl, and; each occurrence of R 1 is independently selected from halo, -OH, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, -O-(C 1 -C 6 alkyl), -O-(C 1 -C 6 haloalkyl), oxo, cyano, and -O-phenyl-F.
A crystalline compound comprising a hydrobromic acid (HBr) salt of a compound of formula I (1-{2-[(2,4-dimethylphenyl)sulfanyl]phenyl}piperazine, INN: vortioxetine), having an XRPD pattern with characteristic peaks (expressed in 2θ ± 0,2° 2θ (CuKα radiation)) at 5.5°, 14.8°, 16.7° and 20.0°.
An inkjet apparatus, comprising: a head configured to discharge liquid through a plurality of nozzles; a tank (305, 306) configured to store the liquid; a circulation unit positioned between the head and the tank (305, 306) and including liquid passages (301, 302) by which the liquid is circulated from the tank (305, 306) to the head and then back to the tank (305, 306), the circulating unit comprising a liquid pump, said liquid pump comprising: a piezoelectric pump unit including an inlet, an outlet, and a chamber formed between the inlet and the outlet, a wall of the chamber including a piezoelectric member; and a control unit configured to apply to the piezoelectric member a first voltage (V1, V1') causing an electric field in a direction in which the polarization of the piezoelectric member becomes stronger and a second voltage (V2, V2') causing an other electric field in a direction in which the polarization of the piezoelectric member is reversed, such that the piezoelectric member is deformed, wherein the first voltage (V1, V1') is greater than the second voltage (V2, V2'), and a total of the first (V1, V1') and second (V2, V2') voltages is maintained to be constant, the control unit being configured to increase the first voltage (V1, V1') and decrease the second voltage (V2, V2'), as the temperature of the liquid increases. a head configured to discharge liquid through a plurality of nozzles; a tank (305, 306) configured to store the liquid; a circulation unit positioned between the head and the tank (305, 306) and including liquid passages (301, 302) by which the liquid is circulated from the tank (305, 306) to the head and then back to the tank (305, 306), the circulating unit comprising a liquid pump, a piezoelectric pump unit including an inlet, an outlet, and a chamber formed between the inlet and the outlet, a wall of the chamber including a piezoelectric member; and a control unit configured to apply to the piezoelectric member a first voltage (V1, V1') causing an electric field in a direction in which the polarization of the piezoelectric member becomes stronger and a second voltage (V2, V2') causing an other electric field in a direction in which the polarization of the piezoelectric member is reversed, such that the piezoelectric member is deformed, wherein the first voltage (V1, V1') is greater than the second voltage (V2, V2'), and a total of the first (V1, V1') and second (V2, V2') voltages is maintained to be constant, the control unit being configured to increase the first voltage (V1, V1') and decrease the second voltage (V2, V2'), as the temperature of the liquid increases.
A method performed by a terminal in a wireless communication system, the method comprising: receiving (920; 1005), from a base station, a radio resource control, RRC, message including first information configuring a medium access control, MAC, parameter for the terminal; identifying second information indicating the terminal whether to skip an uplink transmission, the second information being included in the first information; receiving, from the base station, an uplink grant on a physical downlink control channel, PDCCH, addressed to a cell radio network temporary identifier, C-RNTI; and identifying whether to skip a generation of a MAC protocol data unit, PDU, associated with the uplink grant, based on the second information. receiving (920; 1005), from a base station, a radio resource control, RRC, message including first information configuring a medium access control, MAC, parameter for the terminal; identifying second information indicating the terminal whether to skip an uplink transmission, the second information being included in the first information; receiving, from the base station, an uplink grant on a physical downlink control channel, PDCCH, addressed to a cell radio network temporary identifier, C-RNTI; and identifying whether to skip a generation of a MAC protocol data unit, PDU, associated with the uplink grant, based on the second information.
Lamp comprising - an LED light source for generating a light, - a light guide for guiding the light, - an additional lamp component, wherein the light guide is curved in such a way that it has a convex surface area and a concave surface area and is arranged in such a way that with its concave surface area, it at least partially surrounds the additional lamp component, wherein the lamp furthermore has: - a transparent cover which is shaped and arranged in such a way that it at least partially surrounds the convex surface area of the light guide, - an optically diffusing lobe arranged between the convex surface area of the light guide and the transparent cover, and a carrier element, wherein the cover is designed to be clear and forms a light emission surface of the lamp, characterized in that the cover is arranged to be held on the carrier element via a latching connection, wherein the cover comprises, on its two upper end regions, one latching hook each, which engages the carrier element in a latching manner to form the latching connection in such a way that the light emission surface extends to the upper edge of the lamp. - an LED light source for generating a light, - a light guide for guiding the light, - an additional lamp component, - a transparent cover which is shaped and arranged in such a way that it at least partially surrounds the convex surface area of the light guide, - an optically diffusing lobe arranged between the convex surface area of the light guide and the transparent cover, and
A method, comprising: transmitting a plurality of messages from a communication device for delivery to a corresponding recipient, the plurality of messages being associated with different ones of a plurality of messaging applications executing at the communication device, each of the messaging applications having a corresponding outbound message queue at the communication device; detecting, by a status agent executing at the communication device and being separate to but in communication with the plurality of messaging applications, transmission of each of said plurality of messages, the detecting comprising the status agent monitoring the outbound message queue for each of said plurality of messaging applications; transmitting, by the status agent for receipt by a status service, an outbound message notification for each of said plurality of messages thus transmitted; receiving, by the status agent from the status service, a status update message for each of said plurality of messages, each said status update message indicating delivery of said message to a corresponding receiving communication device; notifying, by the status agent, each of said plurality of messaging applications of delivery of its associated one of the plurality of messages; wherein each of said plurality of messages is transmitted for delivery to the one or more recipients via a messaging infrastructure and the status service is separate from the messaging infrastructure. transmitting a plurality of messages from a communication device for delivery to a corresponding recipient, the plurality of messages being associated with different ones of a plurality of messaging applications executing at the communication device, each of the messaging applications having a corresponding outbound message queue at the communication device; detecting, by a status agent executing at the communication device and being separate to but in communication with the plurality of messaging applications, transmission of each of said plurality of messages, the detecting comprising the status agent monitoring the outbound message queue for each of said plurality of messaging applications; transmitting, by the status agent for receipt by a status service, an outbound message notification for each of said plurality of messages thus transmitted; receiving, by the status agent from the status service, a status update message for each of said plurality of messages, each said status update message indicating delivery of said message to a corresponding receiving communication device; notifying, by the status agent, each of said plurality of messaging applications of delivery of its associated one of the plurality of messages; wherein each of said plurality of messages is transmitted for delivery to the one or more recipients via a messaging infrastructure and the status service is separate from the messaging infrastructure.
A beverage preparation system comprising preparation module for a brewed drink and a milk module for dispensing milk, an outlet (13, 14) for dispensing the brewed drink and milk into a drinking vessel placed under the spout means, and a display device for graphically displaying the dispensed beverage amount in real time, the display device being adapted to displaying a cumulative amount of the dispensed brewed drink and the dispensed milk via a common graphical display element, characterized by first means for determining an amount of the dispensed brewed drink and second means for determining an amount of the dispensed milk, wherein the first and second means are different, and wherein the first means includes a flow meter.
A composition comprising at least one electrode with a covalently attached redox active complex comprising a binding ligand and a solvent accessible transition metal complex which exhibits a change in E 0 upon binding of a target analyte.
A medical device (10, 110, 210, 310, 410), comprising: a flexible hollow tube (20, 120, 220, 320, 420, 520, 620, 720, 820, 920, 1020, 1120, 1220, 1320, 1420, 1520) extending from a proximal end (24, 124, 324) to a distal end (22, 122, 322, 422, 1522) and defining a channel (26, 126, 326) therebetween, a series of openings (28, 128, 328) being defined in a distal portion of the tube allowing for fixation of tissue using suction; characterised in that said medical device further comprises: a flexible member (40, 140, 240, 340, 440) having an initial position disposed alongside the tube and being deployable to a subsequent position in which the flexible member engages a greater curvature of a stomach, the application of suction placing the tube along a lesser curvature of a stomach, fixing anterior and posterior walls of a stomach, and preventing their movement, the tube being visible under stomach tissue, the flexible member being configured to be deployable to automatically assume a shape of a greater curvature of a stomach, the flexible member including a bulging region (42a, 142a, 342a) and a tapering region (42b, 142b, 342b) when deployed, wherein the flexible member includes at least one illumination device.
A vehicle folding rear view mirror support mechanism comprising first and second pivotally interconnected support arm means, a first end (15b1) of the first support arm means being pivoted on a mounting bracket for attachment to the vehicle, a second end (15c1) of the first support arm means being pivotally connected with a first end (16b1) of the second support arm means, and a mirror mount pivotally connected to a second end (16c2) of the second support arm means, the first and second arm means (15, 16) being movable between a retracted reduced width position in which the two arm means are in a side by side substantially parallel relationship and an extended increased width position in which the two arm means are substantially end to end and the mirror mount is supported at its maximum distance from the mounting bracket, the first and second arm means each comprises a pair of arms (15a1, 15a2, 16a 1, 16a2), the arms of each pair extending substantially parallel to each other at all times, characterised in that each arm means (15, 16) is of an elongated L-shaped configuration to allow the arms means to nest closely in their retracted side by side position.
A windscreen wiper device, particularly for automobiles, comprising an elongated wiper blade of a flexible material, which can be placed in abutment with a windscreen to be wiped, which wiper blade is of the flat blade type and includes at least one groove, in which groove an elastic, elongated carrier element is disposed, said wiper blade being biased by said carrier element, wherein said windscreen wiper device further comprises a mounting head for transferring a reciprocal movement to said wiper blade, wherein said windscreen wiper device further comprises a longitudinal strip-shaped arm, wherein said arm near a first end thereof is directly connected to said mounting head and near a second end thereof is directly connected to a connecting device of said wiper blade, and wherein said arm made of a resilient material is biased in order to exert a pressure onto said wiper blade towards said windscreen to be wiped, characterized in that an elongated cap is connected to at least one of the mounting head, the arm and the connecting device, said cap being arranged such that it is connected to the mounting head and snapped onto the arm or such that it is connected to the connecting device and snapped onto the arm.
An assembly comprising: a dilator (30, 50, 60) comprising a shaft (32, 51, 61) having a distal end and a proximal end, the shaft (32, 51, 61) having at least two stiffness sections (32a, 32b, 51a-c, 61a-c), a lumen traversing the shaft (32, 51, 61) from the proximal end to the distal end, and a hub located on the proximal end of the shaft (32, 51, 61); and a sheath having a distal end, a proximal end, and a lumen; wherein the dilator (30, 50, 60) extends through the lumen of the sheath; characterised in that the dilator (30, 50, 60) is removable from the sheath such that, when the dilator (30, 50, 60) is removed from the sheath, the sheath retains a uniform and consistent rigidity throughout its length; and in that the stiffness sections becomes less rigid as they approach the distal end. a dilator (30, 50, 60) comprising a shaft (32, 51, 61) having a distal end and a proximal end, the shaft (32, 51, 61) having at least two stiffness sections (32a, 32b, 51a-c, 61a-c), a lumen traversing the shaft (32, 51, 61) from the proximal end to the distal end, and a hub located on the proximal end of the shaft (32, 51, 61); and a sheath having a distal end, a proximal end, and a lumen; wherein the dilator (30, 50, 60) extends through the lumen of the sheath; characterised in that the dilator (30, 50, 60) is removable from the sheath such that, when the dilator (30, 50, 60) is removed from the sheath, the sheath retains a uniform and consistent rigidity throughout its length; and in that the stiffness sections becomes less rigid as they approach the distal end.
A method, implemented by computer means, for determining a risk score of an eye disease for a user, the method comprising: - a first eye-mediated physiological parameter providing step, during which a first eye-mediated physiological parameter indicative of a first eye-mediated perception or behaviour of the user is provided, - a second eye-mediated physiological parameter providing step, during which a second eye-mediated physiological parameter indicative of a second eye-mediated perception or behaviour of the user is provided, - a life profile data providing step, during which life profile data relative to at least one parameter of the life profile of the user is provided, and - a risk score determining step, during which the risk score of eye disease is determined based on the first eye-mediated physiological parameter, the second eye-mediated physiological parameter and the life profile data. - a first eye-mediated physiological parameter providing step, during which a first eye-mediated physiological parameter indicative of a first eye-mediated perception or behaviour of the user is provided, - a second eye-mediated physiological parameter providing step, during which a second eye-mediated physiological parameter indicative of a second eye-mediated perception or behaviour of the user is provided, - a life profile data providing step, during which life profile data relative to at least one parameter of the life profile of the user is provided, and - a risk score determining step, during which the risk score of eye disease is determined based on the first eye-mediated physiological parameter, the second eye-mediated physiological parameter and the life profile data.
Non-foaming composition comprising, in a physiologically acceptable aqueous medium, a compound of formula below: in which: R 1 represents a radical COOR 3, where R 3 denotes a hydrogen atom or a C 1 -C 4 alkyl radical, which is optionally substituted by one or more hydroxyl groups; R 2 represents a saturated or unsaturated hydrocarbon radical which is linear and has from 1 to 18 carbon atoms or is branched or cyclic and has from 3 to 18 carbon atoms; and also the optical isomers thereof and corresponding salts; and a copolymer of 2-acrylamido-2-methylpropanesulphonic acid and hydroxylated C 2 -C 4 alkyl (meth)acrylate, which is optionally salified. R 1 represents a radical COOR 3, where R 3 denotes a hydrogen atom or a C 1 -C 4 alkyl radical, which is optionally substituted by one or more hydroxyl groups; R 2 represents a saturated or unsaturated hydrocarbon radical which is linear and has from 1 to 18 carbon atoms or is branched or cyclic and has from 3 to 18 carbon atoms; and also the optical isomers thereof and corresponding salts; and a copolymer of 2-acrylamido-2-methylpropanesulphonic acid and hydroxylated C 2 -C 4 alkyl (meth)acrylate, which is optionally salified.
Floating bridge comprising a carriageway, said floating bridge being fastened in two anchoring points on the shore, including power and strength-absorbing structure boxes at least one passage section forming a passage channel for ships and forming a foundation for said carriageway across the passage channel, characterised in that said passage section is a passage float that constitutes a part of the bridge construction and is constructed as a pontoon with the ability to float and having an approximate U-shaped cross section for the formation of said channel, and is fastened to the further power and strength-absorbing structure boxes (10,10') of the floating bridge from each side, such that a major portion of the forces which arise in a length direction of the floating bridge are transferred through the structural boxes and the passage section such that there is formed a continuous transfer of forces through the entire length of the bridge.
A stapling assembly for use with a surgical stapler, comprising a body having a plurality of staples disposed therein, the plurality of staples being configured to be deployed into tissue; and a three-dimensional compressible adjunct (800, 1300, 1500) formed from a matrix comprising at least one fused bioabsorbable polymer and configured to be releasably retained on the body such that the adjunct can be attached to tissue by the plurality of staples in the body, wherein the adjunct has a first stiffness when compressed a first amount and a second stiffness when compressed a second amount greater than the first amount; wherein the adjunct comprises an elongate body comprising struts, wherein each strut has a generally elongate planar configuration, with a first portion of each strut having a narrower width than the width section of a second portion of each strut, such that the struts are wider in the middle and narrower at the ends. a body having a plurality of staples disposed therein, the plurality of staples being configured to be deployed into tissue; and a three-dimensional compressible adjunct (800, 1300, 1500) formed from a matrix comprising at least one fused bioabsorbable polymer and configured to be releasably retained on the body such that the adjunct can be attached to tissue by the plurality of staples in the body, wherein the adjunct has a first stiffness when compressed a first amount and a second stiffness when compressed a second amount greater than the first amount; wherein the adjunct comprises an elongate body comprising struts, wherein each strut has a generally elongate planar configuration, with a first portion of each strut having a narrower width than the width section of a second portion of each strut, such that the struts are wider in the middle and narrower at the ends.
A clathrate compound for agricultural chemical formulation characterized by comprising: a polymolecular host compound as a host compound; and an agricultural chemical active ingredient having a saturated solubility in water at 25 deg. C of not less than 500 ppm, with the exception of benzaldehyde, 2-alkyl-3 -isothiazolones, and 5-chloro-2-methyl-4-isothiazolin-3-one, as a guest compound, wherein the polymolecular host compound is a tetrakisphenol compound represented by formula: (wherein X represents (CH 2) n (n represents an integer of 0 to 3) or a phenylene group which may have a substituent, and R 1 to R 8 each independently represents a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, a phenyl group which may have a substituent, a halogen atom or an alkoxyl group having 1 to 6 carbon atoms); or the polymolecular host compound is a hydroxybenzophenone compound represented by formula: (wherein R 9 and R 10 each independently represents an alkyl group having 1 to 6 carbon atoms, a halogen atom or an alkoxyl group having 1 to 6 carbon atoms, r and s each independently represents an integer of 0 to 4, and p and q each independently represents an integer of 1 to 4). (wherein X represents (CH 2) n (n represents an integer of 0 to 3) or a phenylene group which may have a substituent, and R 1 to R 8 each independently represents a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, a phenyl group which may have a substituent, a halogen atom or an alkoxyl group having 1 to 6 carbon atoms); or the polymolecular host compound is a hydroxybenzophenone compound represented by formula: (wherein R 9 and R 10 each independently represents an alkyl group having 1 to 6 carbon atoms, a halogen atom or an alkoxyl group having 1 to 6 carbon atoms, r and s each independently represents an integer of 0 to 4, and p and q each independently represents an integer of 1 to 4).