A method of creating time lapse video of a live subject, the method comprising: obtaining, by a computer system, a set of digital source images of a region of interest of a live subject, wherein the set of digital source images is captured in a first time period; and normalizing, by the computer system, the set of digital source images; wherein the method further comprises: obtaining, by the computer system, a first representative image that is representative of the digital source images of the region of interest captured in the first time period by synthesizing the first representative image from the set of normalized digital source images, including synthesizing the first representative image by selecting portions of two or more of the digital source images captured in the first time period and combining, by the computer system, the selected portions in a composite image; and combining, by the computer system, the first representative image with one or more additional representative images that are representative of digital source images of the region of interest of the live subject captured in one or more additional time periods to form a time lapse video of the region of interest of the live subject, wherein the one or more additional representative images are selected or synthesized from additional sets of normalized digital source images captured in the one or more respective additional time periods. obtaining, by a computer system, a set of digital source images of a region of interest of a live subject, wherein the set of digital source images is captured in a first time period; and normalizing, by the computer system, the set of digital source images; wherein the method further comprises: obtaining, by the computer system, a first representative image that is representative of the digital source images of the region of interest captured in the first time period by synthesizing the first representative image from the set of normalized digital source images, including synthesizing the first representative image by selecting portions of two or more of the digital source images captured in the first time period and combining, by the computer system, the selected portions in a composite image; and combining, by the computer system, the first representative image with one or more additional representative images that are representative of digital source images of the region of interest of the live subject captured in one or more additional time periods to form a time lapse video of the region of interest of the live subject, wherein the one or more additional representative images are selected or synthesized from additional sets of normalized digital source images captured in the one or more respective additional time periods. obtaining, by the computer system, a first representative image that is representative of the digital source images of the region of interest captured in the first time period by synthesizing the first representative image from the set of normalized digital source images, including synthesizing the first representative image by selecting portions of two or more of the digital source images captured in the first time period and combining, by the computer system, the selected portions in a composite image; and combining, by the computer system, the first representative image with one or more additional representative images that are representative of digital source images of the region of interest of the live subject captured in one or more additional time periods to form a time lapse video of the region of interest of the live subject, wherein the one or more additional representative images are selected or synthesized from additional sets of normalized digital source images captured in the one or more respective additional time periods.