mhurhangee/ep-ind-claims huggingface dataset:
A decorative film (100, 100A, 100B) configured to be provided on a decoration subject, comprising: a base layer containing at least one type of pigment defining a base color; the base layer is configured to be provided on a surface of the decoration subject, and at least one transparent layer (20, 20A, 20B) with the base layer being located between the at least one transparent layer (20, 20A, 20B) and the decoration subject, wherein the transparent layer (20, 20A, 20B) contains a glittering material (21, 23), and a difference (Δh, Δh') between a hue angle of the base color and a hue angle (h2, h3) of a color of the glittering material (21, 23) is 60° or larger and 142° or smaller. a base layer containing at least one type of pigment defining a base color; the base layer is configured to be provided on a surface of the decoration subject, and at least one transparent layer (20, 20A, 20B) with the base layer being located between the at least one transparent layer (20, 20A, 20B) and the decoration subject, wherein the transparent layer (20, 20A, 20B) contains a glittering material (21, 23), and a difference (Δh, Δh') between a hue angle of the base color and a hue angle (h2, h3) of a color of the glittering material (21, 23) is 60° or larger and 142° or smaller.
A cosmetic composition, in particular for application on ageing and/or stressed skin, wherein, apart from water, at least one substance forming lamellar structures with water is present in the composition, and the composition furthermore a) comprises at least one compound containing at least one functional group of the general formula I -CH 2 -N ⊕ -(CH 3) 3 (formula I) b) and at least one additive selected from the group comprising methylglycine, dimethylglycine and methylmethionine, c) and/or contains S-adenosylmethionine, and d) the composition has a lamellar structure such that it has a layered structure in which an upper layer of the substance is oriented towards a lower layer of the substance, respectively, such that the hydrophilic groups of the substance each point outwards, whereas the lipophilic groups of the substance are oriented inwards towards each other, and this lamellar structure is surrounded by water. a) comprises at least one compound containing at least one functional group of the general formula I -CH 2 -N ⊕ -(CH 3) 3 (formula I) b) and at least one additive selected from the group comprising methylglycine, dimethylglycine and methylmethionine, c) and/or contains S-adenosylmethionine, and d) the composition has a lamellar structure such that it has a layered structure in which an upper layer of the substance is oriented towards a lower layer of the substance, respectively, such that the hydrophilic groups of the substance each point outwards, whereas the lipophilic groups of the substance are oriented inwards towards each other, and this lamellar structure is surrounded by water.
A pharmaceutical composition comprising - at least one selective progesterone receptor modulator (SPRM) selected from the group consisting of ulipristral acetate, and its metabolites selected from: and - at least one non-steroidal anti-inflammatory compound selected from the cyclooxygenase type 2 (COX-2) inhibitors. - at least one selective progesterone receptor modulator (SPRM) selected from the group consisting of ulipristral acetate, and its metabolites selected from: and - at least one non-steroidal anti-inflammatory compound selected from the cyclooxygenase type 2 (COX-2) inhibitors.
A system for planning and/or providing neurostimulation for a patient, comprising a pathological spinal cord map storage module for storing at least one pathological spinal cord map describing the activation of the spinal cord of a patient, a healthy spinal cord map storage module for storing at least one reference map describing physiological activation of the spinal cord of at least one healthy subject, an analysis module configured and arranged such that the pathological spinal cord map and the reference map can be compared and/or analyzed automatically such that a deviation map is created, the deviation map describing the difference between the pathological spinal cord map and the reference map, and a compensation module which is configured and arranged to calculate on the basis of the deviation map a neurostimulation protocol for compensating the activation difference between the pathological spinal cord map and the reference map. a healthy spinal cord map storage module for storing at least one reference map describing physiological activation of the spinal cord of at least one healthy subject, an analysis module configured and arranged such that the pathological spinal cord map and the reference map can be compared and/or analyzed automatically such that a deviation map is created, the deviation map describing the difference between the pathological spinal cord map and the reference map, and a compensation module which is configured and arranged to calculate on the basis of the deviation map a neurostimulation protocol for compensating the activation difference between the pathological spinal cord map and the reference map.
A method for detecting at least one mutation in a plurality of cancer-related genes in a subject comprising (a) extracting genomic DNA from a formalin fixed paraffin-embedded tumor sample obtained from the subject; (b) generating a library comprising amplicons corresponding to each of the plurality of cancer-related genes, said plurality of cancer-related genes comprising AKT1, ERBB2, FOXL2, IDH2, NRAS, RET, ALK, ERBB4, GNA11, KIT, PDGFRA, SMO, BRAF, FBXW7, GNAQ, KRAS, PIK3CA, STK11, CTNNB1, FGFR2, GNAS, MAP2K1, PIK3R1, TP53, DDR2, FGFR3, HRAS, MET, PTCH1, EGFR, FGFR4, IDH1, NOTCH1, and PTEN, wherein (i) generating said library involves multiplexed polymerase chain reaction and proceeds independently of using a bait set comprising nucleic acid sequences that are complementary to at least one of the plurality of amplicons; and (ii) the quality of the genomic DNA extracted from the formalin fixed paraffin-embedded tumor sample is not assessed using quantitative PCR prior to generating the library; (c) ligating an adapter sequence to the ends of the plurality of amplicons; and (d) detecting at least one mutation in at least one of the plurality of amplicons using high throughput massive parallel sequencing, wherein the plurality of amplicons is generated by at least two primer pairs disclosed in Table 1, Table 2, or a combination thereof. (a) extracting genomic DNA from a formalin fixed paraffin-embedded tumor sample obtained from the subject; (b) generating a library comprising amplicons corresponding to each of the plurality of cancer-related genes, said plurality of cancer-related genes comprising AKT1, ERBB2, FOXL2, IDH2, NRAS, RET, ALK, ERBB4, GNA11, KIT, PDGFRA, SMO, BRAF, FBXW7, GNAQ, KRAS, PIK3CA, STK11, CTNNB1, FGFR2, GNAS, MAP2K1, PIK3R1, TP53, DDR2, FGFR3, HRAS, MET, PTCH1, EGFR, FGFR4, IDH1, NOTCH1, and PTEN, wherein (i) generating said library involves multiplexed polymerase chain reaction and proceeds independently of using a bait set comprising nucleic acid sequences that are complementary to at least one of the plurality of amplicons; and (ii) the quality of the genomic DNA extracted from the formalin fixed paraffin-embedded tumor sample is not assessed using quantitative PCR prior to generating the library; (i) generating said library involves multiplexed polymerase chain reaction and proceeds independently of using a bait set comprising nucleic acid sequences that are complementary to at least one of the plurality of amplicons; and (ii) the quality of the genomic DNA extracted from the formalin fixed paraffin-embedded tumor sample is not assessed using quantitative PCR prior to generating the library; (c) ligating an adapter sequence to the ends of the plurality of amplicons; and (d) detecting at least one mutation in at least one of the plurality of amplicons using high throughput massive parallel sequencing, wherein the plurality of amplicons is generated by at least two primer pairs disclosed in Table 1, Table 2, or a combination thereof.
A metalized fluoroelastomer material comprising: a) a fluoroelastomer material, bearing b) a layer of titanium metal in direct contact with the fluoroelastomer, and thereupon c) a first metal overlayer in direct contact with the layer of titanium metal, wherein the first metal overlayer comprises a metal selected from the group consisting of copper, noble metals and combinations thereof, wherein the layer of titanium metal has a thickness of between 0.5 and 5.0 nm. a) a fluoroelastomer material, bearing b) a layer of titanium metal in direct contact with the fluoroelastomer, and thereupon c) a first metal overlayer in direct contact with the layer of titanium metal,
A beverage mixing device, comprising: a housing; a dispensing head spaced apart from the housing; a nozzle coupled to the dispensing head; a capsule receiver configured to receive a capsule including a pre-mixed composition, the capsule receiver including a first sensor; a water supply tank disposed within the housing; a carbonation vessel disposed within the housing, the carbonation vessel configured for on-demand carbonation; and a controller in electronic communication with the first sensor, the controller configured to: determine a drink type based on receiving sensor data from the first sensor, and characterized in that the controller is further configured to: dispense a carbonated water or a non-carbonated water based on the drink type. a housing; a dispensing head spaced apart from the housing; a nozzle coupled to the dispensing head; a capsule receiver configured to receive a capsule including a pre-mixed composition, the capsule receiver including a first sensor; a water supply tank disposed within the housing; a carbonation vessel disposed within the housing, the carbonation vessel configured for on-demand carbonation; and a controller in electronic communication with the first sensor, the controller configured to: determine a drink type based on receiving sensor data from the first sensor, and
A topical pharmaceutical composition for use in treating red face related skin disorders, comprising at least 0.02% w/w of berberine or a biologically equivalent analogue of berberine, wherein the biologically equivalent analogue of berberine is selected from the group consisting of jatrorrhizine, palmatine, coptisine, 9-demethylberberine, 9-demethylpalmatine, 13-hydroyberberine, berberrubine, palmatrubine, 9-O-ethylberberrubine, 9-O-ethyl-13-ethylberberrubine, 13-methyldihydroberberine N-methyl salt, tetrahydroprotoberberines and N-methyl salts thereof, and 9-lauroylberberrubine chloride, wherein berberine or the biologically equivalent analogue of berberine is the only pharmaceutically active component, and wherein the red face related skin disorder is selected from the group consisting of rosacea, seborrheic dermatitis, photodermatitis, contact dermatitis, steroid-induced rosacea-like dermatitis, and EGFR inhibitors-induced acneiform dermatitis.
Method for the non-therapeutic treatment of the human body intended to delay the appearance of wrinkles, characterised in that a composition is applied thereto, containing a cosmetically acceptable medium and an effective quantity of at least one N-acyl amino acid chosen from N-palmitoyl glycine and N-palmitoyl isoleucine.
A method for detecting the presence or absence of Vitamin D analogs in a sample comprising the steps of: adding an effective amount of a multiple charge cationic agent to said sample to form a cationic treated sample, said effective amount of a multiple charge cationic agent enhancing the signal from vitamin D analogs upon further analysis by mass spectroscopy, subjecting said cationic treated sample to centrifugation to form a supernatant; loading said supernatant on separation means for separating said Vitamin D analogs from each other non-Vitamin D compound to form an analyte solution, wherein said separation means is protein precipitation, and wherein said protein precipitation is performed by mixing a precipitating agent with said supernatant and separating said protein precipitants from the aqueous solution to form said analyte solution, placing said analyte solution on an analytical column and forming an eluant having said vitamin D analogs separated from each other and from non-vitamin D compounds, and placing said eluant in a mass spectrometer and detecting the presence or absence of Vitamin D analogs in the sample by mass spectrometry. adding an effective amount of a multiple charge cationic agent to said sample to form a cationic treated sample, said effective amount of a multiple charge cationic agent enhancing the signal from vitamin D analogs upon further analysis by mass spectroscopy, subjecting said cationic treated sample to centrifugation to form a supernatant; loading said supernatant on separation means for separating said Vitamin D analogs from each other non-Vitamin D compound to form an analyte solution, wherein said separation means is protein precipitation, and wherein said protein precipitation is performed by mixing a precipitating agent with said supernatant and separating said protein precipitants from the aqueous solution to form said analyte solution, placing said analyte solution on an analytical column and forming an eluant having said vitamin D analogs separated from each other and from non-vitamin D compounds, and placing said eluant in a mass spectrometer and detecting the presence or absence of Vitamin D analogs in the sample by mass spectrometry.
Process for making a stable, intermediate and further curable polyisocyanurate comprising material which comprises free isocyanate groups, has an NCO value of 5-30 % by weight, more preferably an NCO value of 15-25% by weight and wherein the final concentration of the polyisocyanurate compounds does not change more than 10 % from its initial value (calculated as a change in NCO value) when kept at room temperature (around 20 °C) and ambient pressure for minimum 5 hours, most preferably for more than 24 hours which process comprises at least the steps of: - Providing a polyisocyanate composition, and then - Combining and mixing compounds which comprise a group having the structure -CO-NH 2 to the polyisocyanate composition, and subsequently or simultaneously - Combining and mixing a trimerization catalyst compound to the polyisocyanate composition in such amount that the number of equivalents of compounds which comprise a group having the structure -CO-NH 2 over the number of trimerization catalyst equivalents is below 4 and higher than 0.75, preferably in the range between 1 and 3, more preferably in the range between 1 and 2, most preferably in the range between 1 up to 1.5, and then - Allowing the composition to react at a temperature below 90°C, and then - Cooling down the composition to room temperature - Providing a polyisocyanate composition, and then - Combining and mixing compounds which comprise a group having the structure -CO-NH 2 to the polyisocyanate composition, and subsequently or simultaneously - Combining and mixing a trimerization catalyst compound to the polyisocyanate composition in such amount that the number of equivalents of compounds which comprise a group having the structure -CO-NH 2 over the number of trimerization catalyst equivalents is below 4 and higher than 0.75, preferably in the range between 1 and 3, more preferably in the range between 1 and 2, most preferably in the range between 1 up to 1.5, and then - Allowing the composition to react at a temperature below 90°C, and then - Cooling down the composition to room temperature
An electric heating device, in particular for a motor vehicle, with a heat transfer region for transferring the generated heat to a fluid flowing through the electric heating device, wherein a number of electric heating elements arranged between contact plates is provided in the heat transfer region, characterised in that at least one plate-shaped insulating element is further arranged between two contact plates adjacent to at least one electric heating element.
Method for monitoring a cooling power of an air cooling device for cooling an electrical component of an electronics assembly, the cooling device comprising a heat sink, which is thermally coupled to the electrical component, and a fan for generating a cooling air flow over/through the heat sink, the method comprising: heating a thermal element, which is an element separate from the electrical component and is positioned in a region of the cooling air flow; actuating the fan in order to increase the cooling air flow intensity; detecting a temperature (Tk) of the thermal element; and ascertaining a defect of the air cooling device depending on the detected temperature (Tk) of the thermal element following the intended increased cooling air flow intensity. heating a thermal element, which is an element separate from the electrical component and is positioned in a region of the cooling air flow; actuating the fan in order to increase the cooling air flow intensity; detecting a temperature (Tk) of the thermal element; and ascertaining a defect of the air cooling device depending on the detected temperature (Tk) of the thermal element following the intended increased cooling air flow intensity.
A compound of formula or a pharmaceutically acceptable salt thereof, wherein: R x and R y are independently selected from H, a monocyclic heterocyclyl group, a bicyclic aryl group, a bicyclic heterocyclyl group, a tricyclic aryl group, and a tricyclic heterocyclyl group, wherein each heterocyclyl group, wherein each aryl and eachheterocyclyl group are substituted with 0-4 R 1; provided that at least one of R x and R y is other than H; each R 1 is independently selected from halogen, -CN, C 1 -C 3 alkyl, C 1 -C 3 alkoxy, haloC 1 -C 3 alkyl, phenyl, and a monocyclic heterocyclyl group, wherein said phenyl and heterocyclyl groups are substituted with 0-2 R 1a, each R 1a is independently selected from halogen, C 1 -C 3 alkyl, and phenyll; and R 9 is H or C 1 -C 3 alkyl. R x and R y are independently selected from H, a monocyclic heterocyclyl group, a bicyclic aryl group, a bicyclic heterocyclyl group, a tricyclic aryl group, and a tricyclic heterocyclyl group, wherein each heterocyclyl group, wherein each aryl and eachheterocyclyl group are substituted with 0-4 R 1; provided that at least one of R x and R y is other than H; each R 1 is independently selected from halogen, -CN, C 1 -C 3 alkyl, C 1 -C 3 alkoxy, haloC 1 -C 3 alkyl, phenyl, and a monocyclic heterocyclyl group, wherein said phenyl and heterocyclyl groups are substituted with 0-2 R 1a, each R 1a is independently selected from halogen, C 1 -C 3 alkyl, and phenyll; and R 9 is H or C 1 -C 3 alkyl.
Ignition device circuit, especially for a cooking device, with a trigger unit which is designed to trigger an ignition procedure of an ignition unit by means of a reference voltage connection, and with a protective unit having a blocking unit and which is designed, if an electrical connection to the reference voltage connection is established, to block or release the trigger unit as a function of at least one connection variable (V X, R X), characterised in that the connection variable (V X, R X) serves as a differentiating variable for differentiating between an electrical connection to the reference voltage connection, which is established via a contact means, and an unintended electrical connection to an electrical reference voltage connection, which is established via a foreign body.
A power headroom report, PHR, sending method applied for a user terminal, the method comprising: receiving information about an uplink resource set, wherein the uplink resource set comprises uplink resources in at least two cells, the TTI lengths of the at least two cells are different, each uplink resource in the uplink resource set is an uplink resource that is located within duration of a first TTI, and the first TTI is a TTI in a cell that has a maximum TTI length and in which the user terminal is located; determining a target uplink resource, wherein the target uplink resource is an uplink resource that has an earliest start time and that is located within the duration of the first TTI; and sending a PHR on the target uplink resource. receiving information about an uplink resource set, wherein the uplink resource set comprises uplink resources in at least two cells, the TTI lengths of the at least two cells are different, each uplink resource in the uplink resource set is an uplink resource that is located within duration of a first TTI, and the first TTI is a TTI in a cell that has a maximum TTI length and in which the user terminal is located; determining a target uplink resource, wherein the target uplink resource is an uplink resource that has an earliest start time and that is located within the duration of the first TTI; and sending a PHR on the target uplink resource.
An arrangement for controlling a disconnector arranged between power batteries and a consumer side of an electric system of a motor vehicle, in which the electric system comprises at least one power battery, a said disconnector arranged in a conducting line from said power battery to said consumer side and a unit configured to control the disconnector to close or open said conducting line through the disconnector, the arrangement comprising at least one maneuver switch (108, 138) to be manually operated and configured to connect said control unit to said conducting line on a battery side of the disconnector, said maneuver switch comprising • two fixed output contacts (110, 111) each configured to be connected through an output line (112, 113) to said conducting line on the battery side of the disconnector, • two fixed input contacts (114, 115) each configured to be connected through an input line (116, 117) to said control unit, and • two movable contact members (118, 119) movable between a first position of sending a disconnector closing order to the control unit and a second position of sending a disconnector opening order to the control unit, wherein the maneuver (108, 138) switch is configured to in said first position by said movable contact members (118, 119) connect each fixed output contact (110, 111) to a different of said two fixed input contacts (114, 115) than in the second position, and wherein the arrangement comprises a member configured to sense at least one parameter on at least one of said input lines (116, 117) from said maneuver switch (108, 138) to the control unit and a device configured to, on the basis of the result of this sensing action, determine which of said first and second position is assumed by the maneuver switch and inform the control unit of the order so given thereto by the maneuver switch (108, 138). • two fixed output contacts (110, 111) each configured to be connected through an output line (112, 113) to said conducting line on the battery side of the disconnector, • two fixed input contacts (114, 115) each configured to be connected through an input line (116, 117) to said control unit, and • two movable contact members (118, 119) movable between a first position of sending a disconnector closing order to the control unit and a second position of sending a disconnector opening order to the control unit,