A radioisotope concentrator device for use with a radioisotope source, the radioisotope concentrator device comprising: a body having an internal volume in the form of a multiple use sterile disposable cartridge including a concentrator column, a competitive ion selective column, an injection device comprising at least one injection port, one multiple way valve, one entry port at a lower location, and at least one exit port at an upper location, all being in fluid communication; the concentrator column disposed within the internal volume being adapted for selectively capturing at least one radioisotope from a radioisotope solution obtained from a radioisotope source in use; and the body having shielding means for shielding at least the concentrator column in use; the competitive ion selective column disposed within the internal volume being adapted for removing at least one competitive ion from the radioisotope solution obtained from the radioisotope source in use; the at least one injection port adapted to receive an injection device, and the at least one injection port being operably connected to the concentrator column; the one multiple way valve being configurable between a first open configuration for allowing fluid communication between the competitive ion selective column and the concentrator column in use and a second open configuration for allowing fluid communication between the at least one injection port and the concentrator column to elute the at least one radioisotope from the concentrator column with an eluent; and wherein the at least one exit port, being in fluid communication with the internal volume is able to connect to an evacuated vial in use to effect, by the vacuum provided by a waste vial, the fluid communication in the first open configuration or in the second open configuration and whereby the vacuum within the evacuated vial imparts a negative pressure on the system causing the solution of the radioisotope with the eluent to be drawn up through the competitive ion selective column and the concentrator column into the vial. a body having an internal volume in the form of a multiple use sterile disposable cartridge including a concentrator column, a competitive ion selective column, an injection device comprising at least one injection port, one multiple way valve, one entry port at a lower location, and at least one exit port at an upper location, all being in fluid communication; the concentrator column disposed within the internal volume being adapted for selectively capturing at least one radioisotope from a radioisotope solution obtained from a radioisotope source in use; and the body having shielding means for shielding at least the concentrator column in use; the competitive ion selective column disposed within the internal volume being adapted for removing at least one competitive ion from the radioisotope solution obtained from the radioisotope source in use; the at least one injection port adapted to receive an injection device, and the at least one injection port being operably connected to the concentrator column; the one multiple way valve being configurable between a first open configuration for allowing fluid communication between the competitive ion selective column and the concentrator column in use and a second open configuration for allowing fluid communication between the at least one injection port and the concentrator column to elute the at least one radioisotope from the concentrator column with an eluent; and wherein the at least one exit port, being in fluid communication with the internal volume is able to connect to an evacuated vial in use to effect, by the vacuum provided by a waste vial, the fluid communication in the first open configuration or in the second open configuration and whereby the vacuum within the evacuated vial imparts a negative pressure on the system causing the solution of the radioisotope with the eluent to be drawn up through the competitive ion selective column and the concentrator column into the vial.