mhurhangee/ep-ind-claims huggingface dataset:
A pharmaceutical composition comprising a plurality of active agents in a therapeutically effective amount and one or more pharmaceutical excipients, characterized in that a. at least one active agent inhibits VEGF's and/or VEGFR1-3 signaling, wherein the at least one VEGF's and/or VEGFR1-3 inhibitor is cabozantinib, b. at least one active agent inhibits SDF1alpha and/or CXCR4 signaling, wherein the at least one SDF1alpha and/or CXCR4 inhibitor is plerixafor, c. at least one active agent inhibits EGF and/or EGFR1-3 signaling, wherein the at least one EGF and/or EGFR1-3 inhibitor is afatinib, d. at least one active agent inhibits COX2 and/or PGE2 and/or EP signaling, wherein the at least one COX2 and/or PGE2 inhibitor is etoricoxib and e. at least one active agent inhibits HGF and/or HGFR signaling, wherein the at least one HGF and/or HGFR inhibitor is cabozantinib. a. at least one active agent inhibits VEGF's and/or VEGFR1-3 signaling, wherein the at least one VEGF's and/or VEGFR1-3 inhibitor is cabozantinib, b. at least one active agent inhibits SDF1alpha and/or CXCR4 signaling, wherein the at least one SDF1alpha and/or CXCR4 inhibitor is plerixafor, c. at least one active agent inhibits EGF and/or EGFR1-3 signaling, wherein the at least one EGF and/or EGFR1-3 inhibitor is afatinib, d. at least one active agent inhibits COX2 and/or PGE2 and/or EP signaling, wherein the at least one COX2 and/or PGE2 inhibitor is etoricoxib and e. at least one active agent inhibits HGF and/or HGFR signaling, wherein the at least one HGF and/or HGFR inhibitor is cabozantinib.
A method for manufacturing a Z-directed component for insertion into a mounting hole in a printed circuit board, comprising: extruding a substrate material through an extrusion die (700, 720) having a chamber (703, 723) defining the shape of the extruded substrate material including forming at least one channel through the substrate material with a corresponding projection (704, 705, 706, 724) in the extrusion die; dividing the extruded substrate material into a plurality of layers of the Z-directed component according to the thickness of each layer; applying a conductive material to a surface of at least one of the layers; and combining a stack of the layers to form the Z-directed component. extruding a substrate material through an extrusion die (700, 720) having a chamber (703, 723) defining the shape of the extruded substrate material including forming at least one channel through the substrate material with a corresponding projection (704, 705, 706, 724) in the extrusion die; dividing the extruded substrate material into a plurality of layers of the Z-directed component according to the thickness of each layer; applying a conductive material to a surface of at least one of the layers; and combining a stack of the layers to form the Z-directed component.
An aqueous oral care composition comprising from 0.125 wt% to 0.75 wt% of stannous chloride, wherein the composition comprises from 50 wt% to 65 wt% water, and a polyphosphate tartar control agent.
Device for electrically contacting an electrically heatable catalytic converter in an exhaust system for motor vehicles with internal combustion engines for treating exhaust gases, which device is designed for electrically contacting a plurality of conductor tracks, which are arranged within an interior space that is surrounded by an outer wall of the device, through the outer wall, wherein one or more electrodes (9, 10) which can be electrically contacted through the outer wall are arranged in the interior space, each of which electrodes electrically contacts two or more of the conductor tracks in the interior space, wherein the device has, in the interior space, one or more conductor track carriers which each carry one of the conductor tracks, characterized in that in each case one of the conductor tracks is arranged on a surface of a respective conductor track carrier and an electrically insulating insulation coating, which is interrupted above a contact area (7, 8) of the conductor track for electrically contacting the conductor track in order to electrically contact the conductor track through the outer wall, is formed on the surface and the conductor track.
An ice maker, wherein the ice maker comprises an ice bin for receiving ice cubes, and an ice making and removing structure rotatably provided in the ice bin, the ice making and removing structure comprises a bracket rotatably disposed in the ice bin via a rotating shaft, and an ice making box disposed in the bracket, the bracket is operable to drive the ice making box to rotate relative to the ice bin to open or close the ice bin, the ice making box is driven to rotate relative to the bracket between an ice making position and an ice turning position, and the ice making box defines a plurality of ice making cells, when the ice making box is in the ice making position, the opening of the ice making cells faces upwards; and when the ice box is in the ice turning position, the opening of the ice making cells faces the inside of the ice bin, characterized in that the ice maker further comprises an ice shovel and a holding portion, and the ice shovel has an accommodating cavity for accommodating water, at least one of sides forming the accommodating cavity is provided with an ice shoveling portion, and the ice shoveling portion protrudes from other sides forming the accommodating cavity to shovel the ice, the ice bin is provided with an ice shovel positioning structure to position the ice shovel in the ice bin, the ice shovel positioning structure comprises a stop rib disposed in the ice bin, and a groove provided on one of the side walls of the ice bin, and the ice shoveling portion abuts against the stop rib, and the holding portion fits in the groove and is received in the groove, and the ice bin comprises a bottom wall facing the ice making box, and an opening of the accommodating cavity faces the bottom wall when the ice shovel is placed in the ice bin. characterized in that the ice maker further comprises an ice shovel and a holding portion, and the ice shovel has an accommodating cavity for accommodating water, at least one of sides forming the accommodating cavity is provided with an ice shoveling portion, and the ice shoveling portion protrudes from other sides forming the accommodating cavity to shovel the ice, the ice bin is provided with an ice shovel positioning structure to position the ice shovel in the ice bin, the ice shovel positioning structure comprises a stop rib disposed in the ice bin, and a groove provided on one of the side walls of the ice bin, and the ice shoveling portion abuts against the stop rib, and the holding portion fits in the groove and is received in the groove, and the ice bin comprises a bottom wall facing the ice making box, and an opening of the accommodating cavity faces the bottom wall when the ice shovel is placed in the ice bin.
An air cleaner ( 30, 200) for a stratified scavenging two-stroke internal combustion engine, the air cleaner ( 30, 200) comprising: an element member provided with a cleaner element filtering air; a first inlet through which air filtered by the cleaner element is drawn in and fed to an air passage in an intake system of the engine; a second inlet which is located away from the first inlet and through which air filtered by the cleaner element is drawn in and fed to an air-fuel mixture passage in the intake system of the engine; and a passage forming member ( 70, 204) forming an extended passage leading to the first inlet or the second inlet, wherein the passage forming member ( 70, 204) is shaped to surround a periphery of the first inlet or the second inlet, and the passage forming member ( 70, 204) forms a blown-back fuel diffusion preventing region leading to the first inlet or the second inlet independent from the extended passage, characterized in that, the passage forming member ( 70, 204) has an entrance opening at one end in a longitudinal direction of the passage forming member ( 70, 204) and an exit opening at another end, and the blown-back fuel diffusion preventing region is opened to an air cleaner clean space defined by the cleaner element through a first clearance gap between the entrance opening and the exit opening. an element member provided with a cleaner element filtering air; a first inlet through which air filtered by the cleaner element is drawn in and fed to an air passage in an intake system of the engine; a second inlet which is located away from the first inlet and through which air filtered by the cleaner element is drawn in and fed to an air-fuel mixture passage in the intake system of the engine; and a passage forming member ( 70, 204) forming an extended passage leading to the first inlet or the second inlet, wherein the passage forming member ( 70, 204) is shaped to surround a periphery of the first inlet or the second inlet, and the passage forming member ( 70, 204) forms a blown-back fuel diffusion preventing region leading to the first inlet or the second inlet independent from the extended passage,
Process for producing magnetic composites, which comprises electrophoretic deposition of hard-magnetic particles and soft-magnetic particles on an electrode.
A MEMS device, the device comprising: a membrane; a reinforced backplate having a plurality of openings, the reinforced backplate including a first layer and a second layer; an interconnect layer positioned between the first and second layers (200a, 200b), wherein the first laver and the second laver contact one another and are coupled together by the interconnect layer, characterized in that the interconnect layer has a smaller width than the first and second layers (200a, 200b). a membrane; a reinforced backplate having a plurality of openings, the reinforced backplate including a first layer and a second layer; an interconnect layer positioned between the first and second layers (200a, 200b), wherein the first laver and the second laver contact one another and are coupled together by the interconnect layer, characterized in that the interconnect layer has a smaller width than the first and second layers (200a, 200b).
Lighting apparatus, comprising a main body (10; 100) having a side wall extending around a longitudinal body axis from a base suitable for being fixed to the ground, and a lighting head (12; 112) connected to said main body, wherein: - the main body (10; 110) has an upper portion (16; 116) which extends from the side wall and which forms, at least in a peripheral sector, a reflective slide (18; 118) suitable for reflecting the light generated by the lighting head (12; 112); - the main body (10; 110) terminates at the top with a head support neck which extends in height coaxially with the longitudinal body axis and which has a radial extension smaller than the radial extension of the main body (10; 110) and the lighting head (12; 112), the reflecting slide (18; 118) extending between said head support neck and the upper edge of the side wall; - the lighting head (12; 112) houses a lighting source (14; 114) suitable for projecting a beam of light downwards, above the reflecting slide (18; 118); - the lighting head (12; 112) is fixed exclusively to the head support neck by means of fixing means hidden from view, wherein the fixing means act axially between the support neck and an inner central portion of the lighting head (12; 112), the apparatus being characterized in that said fixing means consist of fixing screws supported by the head support neck and screwed into respective threaded seats formed in said inner central portion of the lighting head, the fixing screws having the respective heads accessible from inside the upper portion. - the main body (10; 110) has an upper portion (16; 116) which extends from the side wall and which forms, at least in a peripheral sector, a reflective slide (18; 118) suitable for reflecting the light generated by the lighting head (12; 112); - the main body (10; 110) terminates at the top with a head support neck which extends in height coaxially with the longitudinal body axis and which has a radial extension smaller than the radial extension of the main body (10; 110) and the lighting head (12; 112), the reflecting slide (18; 118) extending between said head support neck and the upper edge of the side wall; - the lighting head (12; 112) houses a lighting source (14; 114) suitable for projecting a beam of light downwards, above the reflecting slide (18; 118); - the lighting head (12; 112) is fixed exclusively to the head support neck by means of fixing means hidden from view, wherein the fixing means act axially between the support neck and an inner central portion of the lighting head (12; 112), the apparatus being characterized in that said fixing means consist of fixing screws supported by the head support neck and screwed into respective threaded seats formed in said inner central portion of the lighting head, the fixing screws having the respective heads accessible from inside the upper portion.
A load control system for controlling one or more electrical loads (112, 122), the load control system comprising: a plurality of control devices (110, 140, 150, 160) each comprising a user interface configured to receive a user input and each configured to control at least one of the one or more electrical loads (112, 122), wherein the user interface includes an illuminated portion; and a first daylight sensor external to at least one of the plurality of control devices (110, 140, 150, 160) and configured to sense a light level in a space in which the plurality of control devices (110, 140, 150, 160) is installed; characterized in that a first control device of the plurality of control devices (110, 140, 150,160) comprises the first daylight sensor, and the plurality of control devices (110, 140, 150, 160) are each configured to receive a signal indicative of the light level sensed by the first daylight sensor; wherein the plurality of control devices (110, 140, 150, 160) are configured to control their respective illuminated portions in proportion to the light level sensed by the first daylight sensor. a plurality of control devices (110, 140, 150, 160) each comprising a user interface configured to receive a user input and each configured to control at least one of the one or more electrical loads (112, 122), wherein the user interface includes an illuminated portion; and a first daylight sensor external to at least one of the plurality of control devices (110, 140, 150, 160) and configured to sense a light level in a space in which the plurality of control devices (110, 140, 150, 160) is installed; characterized in that a first control device of the plurality of control devices (110, 140, 150,160) comprises the first daylight sensor, and the plurality of control devices (110, 140, 150, 160) are each configured to receive a signal indicative of the light level sensed by the first daylight sensor; wherein the plurality of control devices (110, 140, 150, 160) are configured to control their respective illuminated portions in proportion to the light level sensed by the first daylight sensor.
A waveguide pupil expander for an automotive head-up display, the waveguide pupil expander comprising: first and second substantially planar reflective surfaces (710,720) arranged in parallel having an optically transparent material therebetween, and an input port for receiving input light; wherein the first reflective surface is fully reflective and the second reflective surface is partially reflective such that input light is guided from the input port to an output port at the second partially reflective surface by a series of internal reflections; wherein the waveguide is formed by a layered glass structure arranged to maintain the integrity of the waveguide in the event of breakage of glass; and wherein the layered glass structure comprises a glass layer and a polymer-based layer comprising a polymer-based louvre comprising a plurality of parallel polymer-based slats; and characterised in that the glass layer is laminated with the polymer-based layer comprising a polymer-based louvre, wherein the spacing between the slats is chosen to optimise the integrity of the waveguide upon breakage based on the materials and dimensions thereof. first and second substantially planar reflective surfaces (710,720) arranged in parallel having an optically transparent material therebetween, and an input port for receiving input light; wherein the first reflective surface is fully reflective and the second reflective surface is partially reflective such that input light is guided from the input port to an output port at the second partially reflective surface by a series of internal reflections; wherein the waveguide is formed by a layered glass structure arranged to maintain the integrity of the waveguide in the event of breakage of glass; and wherein the layered glass structure comprises a glass layer and a polymer-based layer comprising a polymer-based louvre comprising a plurality of parallel polymer-based slats; and characterised in that the glass layer is laminated with the polymer-based layer comprising a polymer-based louvre, wherein the spacing between the slats is chosen to optimise the integrity of the waveguide upon breakage based on the materials and dimensions thereof.
Method for the manufacture of a packed product, comprising the steps of: a) bringing a product into a superheated steam atmosphere with an O 2 content of maximum 10 vol.-%, a pressure of between 950 mbar and 1100 mbar and a temperature of at least 100°C, b) making available a packing container in the superheated steam atmosphere and filling the packing container with a predetermined quantity of the product, wherein a residual volume of the packing container not filled with product is filled with the superheated steam atmosphere, c) replacing at least 50% of the residual volume of superheated steam atmosphere in the packing container by a sterile inert gas, by means of a gas supply pipe, d) sealing the packing container, and e) cooling the packing container and the product contained therein, characterized in that in step c) the gas supply pipe, as the result of a relative motion between the gas supply pipe and the packing container, immerges into the packing container, so that a gas discharge opening of the gas supply pipe is located in the region of a bottom of the packing container, nearer to the bottom than to an open seal opening of the packing container. a) bringing a product into a superheated steam atmosphere with an O 2 content of maximum 10 vol.-%, a pressure of between 950 mbar and 1100 mbar and a temperature of at least 100°C, b) making available a packing container in the superheated steam atmosphere and filling the packing container with a predetermined quantity of the product, wherein a residual volume of the packing container not filled with product is filled with the superheated steam atmosphere, c) replacing at least 50% of the residual volume of superheated steam atmosphere in the packing container by a sterile inert gas, by means of a gas supply pipe, d) sealing the packing container, and e) cooling the packing container and the product contained therein,
A circuit board comprising: a substrate; a conductor layer located on the substrate; a reflective layer located on the conductor layer; and a resin layer located on the substrate to be in contact with the conductor layer and the reflective layer, wherein in a surface of the reflective layer, arithmetic mean roughness Ra obtained from a roughness profile is less than 0.2 um and a ratio of kurtosis Rku obtained from the roughness profile to skewness Rsk obtained from the roughness profile is 5 or more and 15 or less, characterised in that, in the surface of the reflective layer, a reduced valley depth Rvk obtained from a roughness profile is smaller than a reduced peak height Rpk obtained from the roughness profile. a substrate; a conductor layer located on the substrate; a reflective layer located on the conductor layer; and a resin layer located on the substrate to be in contact with the conductor layer and the reflective layer, wherein in a surface of the reflective layer, arithmetic mean roughness Ra obtained from a roughness profile is less than 0.2 um and a ratio of kurtosis Rku obtained from the roughness profile to skewness Rsk obtained from the roughness profile is 5 or more and 15 or less, characterised in that, in the surface of the reflective layer, a reduced valley depth Rvk obtained from a roughness profile is smaller than a reduced peak height Rpk obtained from the roughness profile.
A method performed by a network node for scheduling a system information block type 1 for narrow band communication, SIB1-NB, for a time division duplex, TDD transmission, the method comprising: indicating a SIB1-NB scheduling information for TDD in a master information block, MIB, wherein the SIB1-NB scheduling information indicates that the SIB1-NB transmission is on one of an anchor carrier and a non-anchor carrier and wherein the scheduling information comprises a parameter associated with a predefined entry in at least one TDD-specific table, wherein separate TDD-specific tables are specified for the anchor carrier and for the non-anchor carrier, the predefined entry comprising: at least one subframe for the SIB1-NB transmission; a number of repetitions of the SIB1-NB transmission; and a transport block size, TBS, for the SIB1-NB transmission. at least one subframe for the SIB1-NB transmission; a number of repetitions of the SIB1-NB transmission; and a transport block size, TBS, for the SIB1-NB transmission.
An apparatus comprising: a charge-domain pipeline having at least a first stage (81, 101) propagating charge toward a second stage (82, 103); a comparison circuit to compare a reference voltage (V REF, V CM-REF) against an output voltage, the output voltage corresponding to a common-mode charge at the second stage (82, 103) of the charge-domain pipeline; and a control circuit to control a common-mode charge output at the first stage (81, 101), based on the comparison circuit, such that common-mode charge at the second stage (82, 103) is adjusted, a charge-domain pipeline having at least a first stage (81, 101) propagating charge toward a second stage (82, 103); a comparison circuit to compare a reference voltage (V REF, V CM-REF) against an output voltage, the output voltage corresponding to a common-mode charge at the second stage (82, 103) of the charge-domain pipeline; and a control circuit to control a common-mode charge output at the first stage (81, 101), based on the comparison circuit, such that common-mode charge at the second stage (82, 103) is adjusted,
Method for automatically actuating a closing element (1; 2) of a vehicle, wherein an object is detected by means of an optical sensor, wherein the closing element (1; 2) is actuated as a function of the detection of the object, wherein with the optical sensor it is checked whether an obstacle is located in a movement path of the closing element (1; 2) during the actuation of the closing element (1; 2), and wherein the actuation of the closing element (1; 2) is interrupted if the optical sensor detects an obstacle in the movement path of the closing element (1; 2), characterized in that it is checked whether the key which is assigned to the vehicle is detected when it is detected with the optical sensor that the object has approached a handle (3; 4) of the closing element (1; 2) up to a predetermined distance.