Use of a steroid sulfatase inhibitor, as well as pharmaceutically acceptable salts thereof, for the preparation of a pharmaceutical composition for the treatment or prophylaxis of a disease or condition associated with premature uterine contractions wherein the steroid sulfatase inhibitor is a sulfamate of Formula: wherein R 1 and R 2 are independently selected from H, optionally substituted C 1 -C 6 alkyl, optionally substituted C 2 -C 6 alkenyl, optionally substituted C 2 -C 6 alkynyl, alkoxy, optionally substituted C 3 -C 8 -cycloalkyl, optionally substituted heterocycloalkyl, optionally substituted acyl, aryl, heteroaryl, optionally substituted C 1 -C 6 alkyl aryl, optionally substituted C 1 -C 6 alkyl heteroaryl, optionally substituted C 1 -C 6 alkyl C 3 -C 8 -cycloalkyl, optionally substituted C 1 -C 6 optionally substituted alkyl heterocycloalkyl, optionally substituted aryl C 1 -C 6 alkyl, optionally substituted heteroaryl C 1 -C 6 alkyl, optionally substituted C 3 -C 8 -cycloalkyl C 1 -C 6 alkyl and optionally substituted heterocycloalkyl C 1 -C 6 alkyl or R 1 and R 2 form together an optionally substituted alkenyl group; R 3 is a group selected from a group of Formulae (II'), (II"), (III') and (IV'): wherein R 4 and R 5 are independently selected from H; halogen; nitro; optionally substituted amino; optionally substituted sulfanyl; optionally substituted acyl; optionally substituted thioalkyl; optionally substituted C 1 -C 6 alkyl; optionally substituted C 2 -C 6 alkenyl; optionally substituted alkoxy; optionally substituted alkoxy alkyl, optionally substituted amino alkyl; optionally substituted C 3 -C 8 -cycloalkyl; and optionally substituted aryl; R 6, R 7, R 8, R 9, R 10, R 11, R 12, R 13 and R 14 are independently selected from H; OH; halogen and optionally substituted C 1 -C 6 alkyl; R 15 is selected from selected from H; OH; halogen; sulfamate and optionally substituted C 1 -C 6 alkyl; R 16, R 17 and R 18 are independently selected from H; OH; halogen; optionally substituted C 1 -C 6 alkyl; optionally substituted C 2 -C 6 alkenyl; optionally substituted alkoxy; optionally substituted acylamino; amino and optionally substituted sulfonyl; R 24 and R 25 are independently selected from H; OH; halogen; optionally substituted C 1 -C 6 alkyl; optionally substituted C 2 -C 6 alkenyl; optionally substituted alkoxy; optionally substituted acylamino; optionally substituted amino and optionally substituted sulfonyl; Y is selected from optionally substituted acyl; optionally substituted alkoxy; -C -; optionally substituted C 1 -C 6 alkyl; optionally substituted C 2 -C 6 alkenyl; optionally substituted C 2 -C 6 alkynyl; C=N-OR 29 and CR 26 R 27; R 26 and R 27 are independently selected from H; OH; nitrile; optionally substituted sulfamate; optionally substituted alkoxy; optionally substituted carbonyl; optionally substituted amino; optionally substituted nitrile; optionally substituted C 1 -C 6 alkyl; optionally substituted C 2 -C 6 alkenyl; optionally substituted aryl; optionally substituted heteroaryl; optionally substituted aryl C 1 -C 6 alkyl; optionally substituted aminocarbonyl; optionally substituted acylamino; optionally substituted alkoxycarbonyl; and optionally substituted sulfonyloxy; R 28 is selected from H; OH; optionally substituted C 1 -C 6 alkyl; optionally substituted C 2 -C 6 alkenyl; optionally substituted aryl C 1 -C 6 alkyl; optionally substituted heteroaryl C 1 -C 6 alkyl; optionally substituted C 3 -C 8 -cycloalkyl C 1 -C 6 alkyl such as optionally substituted cyclopropyl methyl; optionally substituted aryl; optionally substituted heteroaryl; optionally substituted C 3 -C 8 -cycloalkyl; and optionally substituted heterocycloalkyl; R 29 is selected from H; optionally substituted C 1 -C 6 alkyl and optionally substituted carbonyl; X is selected from N and O; Z is CR 30; R 30 is selected from H and optionally substituted C 1 -C 6 alkyl; n is an integer selected from 3 to 14.