A method for detecting a pathogen comprising: adding a test subject sample fluid to a replaceable aptamer molecular photonic beacon test vial, the test subject sample fluid comprising a solution of Aptamer Molecular Photonic Beacons and a carrier liquid medium, wherein the Aptamer Molecular Photonic Beacons are selected to bind to a protein, RNA or DNA of a target pathogen and further comprise a reporter molecule and a quencher molecule, the reporter molecule being operable to receive light and emit light after binding to the target pathogen, the binding modifying a configuration of the Aptamer Molecular Photonic Beacons from a quenched configuration, where the quencher molecule is in proximity with the reporter molecule, to an emitting configuration where the quencher molecule and the reporter molecule are separated, the aptamer molecular beacon molecules having a stem sequence, a loop sequence, a fluorophore reporter as the reporter and the quencher in an unbound state in which the quencher is proximate the fluorophore reporter to prevent fluorescence, wherein the stem sequence selectively binds to the target pathogen to become in a bound state in which the quencher is remote from the fluorophore reporter to allow fluorescence, and an excitation wavelength of the fluorophore reporter is between 450 nm and 470 nm; aligning a camera and a flash light source of a mobile computing device with at least one aperture of a light proof enclosure of a testing device fixture and aligning the camera with a filter, which is a notch optical filter specific to 490 nm such as a bandpass filter with a narrow band around 490 nm, the flash light source of the mobile computing device being made of Light Emitting Diodes that have a fundamental light emission between 450 to 460 nm and the fluorophore emitting light at around 490 nm; inserting the aptamer molecular photonic beacon test vial in a test vial receptacle of the testing device fixture; using a software testing application on the mobile computing device to perform a test to detect a presence of the target pathogen by operating the flash light to illuminate the solution in the vial to excite said reporter molecule and acquiring at least one image of emission from the reporter molecule using the camera, wherein performing the test includes causing the camera to capture an image of the replaceable aptamer molecular photonic beacon test vial to acquire the at least one image of emission from the reporter molecule; and using the software testing application on the mobile computing device for at least one of computing an infection status based on the captured image and displaying the infection status on a display of the mobile computing device. adding a test subject sample fluid to a replaceable aptamer molecular photonic beacon test vial, the test subject sample fluid comprising a solution of Aptamer Molecular Photonic Beacons and a carrier liquid medium, wherein the Aptamer Molecular Photonic Beacons are selected to bind to a protein, RNA or DNA of a target pathogen and further comprise a reporter molecule and a quencher molecule, the reporter molecule being operable to receive light and emit light after binding to the target pathogen, the binding modifying a configuration of the Aptamer Molecular Photonic Beacons from a quenched configuration, where the quencher molecule is in proximity with the reporter molecule, to an emitting configuration where the quencher molecule and the reporter molecule are separated, the aptamer molecular beacon molecules having a stem sequence, a loop sequence, a fluorophore reporter as the reporter and the quencher in an unbound state in which the quencher is proximate the fluorophore reporter to prevent fluorescence, wherein the stem sequence selectively binds to the target pathogen to become in a bound state in which the quencher is remote from the fluorophore reporter to allow fluorescence, and an excitation wavelength of the fluorophore reporter is between 450 nm and 470 nm; aligning a camera and a flash light source of a mobile computing device with at least one aperture of a light proof enclosure of a testing device fixture and aligning the camera with a filter, which is a notch optical filter specific to 490 nm such as a bandpass filter with a narrow band around 490 nm, the flash light source of the mobile computing device being made of Light Emitting Diodes that have a fundamental light emission between 450 to 460 nm and the fluorophore emitting light at around 490 nm; inserting the aptamer molecular photonic beacon test vial in a test vial receptacle of the testing device fixture; using a software testing application on the mobile computing device to perform a test to detect a presence of the target pathogen by operating the flash light to illuminate the solution in the vial to excite said reporter molecule and acquiring at least one image of emission from the reporter molecule using the camera, wherein performing the test includes causing the camera to capture an image of the replaceable aptamer molecular photonic beacon test vial to acquire the at least one image of emission from the reporter molecule; and using the software testing application on the mobile computing device for at least one of computing an infection status based on the captured image and displaying the infection status on a display of the mobile computing device.