A pneumatic tire that mounts on a vehicle where, when mounted on the vehicle, a first side in a tire width direction corresponds to a vehicle outer side and a second side that is an opposite side of the first side in the tire width direction corresponds to a vehicle inner side, wherein a region of a tread surface of the pneumatic tire comprises: four circumferential main grooves (58, 54, 52, 56) extending in a tire circumferential direction; five land portions (68, 64, 60, 62, 66) partitioned by the circumferential main grooves (58, 54, 52, 56); first shoulder inclined grooves that are formed in a region of a first side shoulder land portion, from among the land portions (68, 64, 60, 62, 66), positioned on an outermost side in the tire width direction on the first side and extend in the tire width direction; and second side shoulder inclined grooves that are formed in a region of a second side shoulder land portion positioned on an outermost side in the tire width direction on the second side and extend in the tire width direction; characterized in that the region of the tread surface comprises chamfers formed on an entire periphery of an edge where the first side shoulder land portion contacts the first side shoulder inclined grooves and an entire periphery of an edge where the second side shoulder land portion contacts the second side shoulder inclined grooves; a ratio W 2/ W 1 that represents a ratio of a groove width2 of a second circumferential main groove located at a second position when viewed from the first side to a groove width W 1 of a first circumferential main groove located at a first position when viewed from the first side from among the four circumferential main grooves (58, 54, 52, 56) ranges 4 to 5 and W 2 is in a range of 16 to 20 mm; and a ratio S in /S out that represents a ratio of a groove surface area ratio S in in a region located on the second side when viewed from a tire centerline to a groove surface area ratio S out in a region located on the first side when viewed from the tire centerline in the region of the tread surface ranges 1.1 to 1.2 and S in is in a range of 35.2 to 38.4%. four circumferential main grooves (58, 54, 52, 56) extending in a tire circumferential direction; five land portions (68, 64, 60, 62, 66) partitioned by the circumferential main grooves (58, 54, 52, 56); first shoulder inclined grooves that are formed in a region of a first side shoulder land portion, from among the land portions (68, 64, 60, 62, 66), positioned on an outermost side in the tire width direction on the first side and extend in the tire width direction; and second side shoulder inclined grooves that are formed in a region of a second side shoulder land portion positioned on an outermost side in the tire width direction on the second side and extend in the tire width direction; characterized in that the region of the tread surface comprises chamfers formed on an entire periphery of an edge where the first side shoulder land portion contacts the first side shoulder inclined grooves and an entire periphery of an edge where the second side shoulder land portion contacts the second side shoulder inclined grooves; a ratio W 2/ W 1 that represents a ratio of a groove width2 of a second circumferential main groove located at a second position when viewed from the first side to a groove width W 1 of a first circumferential main groove located at a first position when viewed from the first side from among the four circumferential main grooves (58, 54, 52, 56) ranges 4 to 5 and W 2 is in a range of 16 to 20 mm; and a ratio S in /S out that represents a ratio of a groove surface area ratio S in in a region located on the second side when viewed from a tire centerline to a groove surface area ratio S out in a region located on the first side when viewed from the tire centerline in the region of the tread surface ranges 1.1 to 1.2 and S in is in a range of 35.2 to 38.4%.