mhurhangee/ep-ind-claims huggingface dataset:
A combination of a first compound selected from N-(3,5-dimethoxyphenyl)-N'-(1-methylethyl)-N-[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine or a pharmaceutically acceptable salt thereof or a solvate thereof, and N-(2-fluoro-3,5-dimethoxyphenyl)-N-(1H-imidazol-2-ylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)pyrido[2,3-b]pyrazin-6-amine or a pharmaceutically acceptable salt thereof or a solvate thereof; and a second compound which is a cMet inhibitor for use to delay emergence of resistance of a tumour or a cancer to the first compound of the combination.
A system configured for segmenting an image comprising one or more anatomical structures into segments, the system comprising: a memory comprising instruction data representing a set of instructions; a processor configured to communicate with the memory and to execute the set of instructions, wherein the set of instructions, when executed by the processor, cause the processor to: receive a first user input indicating a line in the image; define two regions in the image, one on either side of the indicated line, each region a butting the indicated line on its respective side; and for each of the two regions: determine a segment corresponding to an anatomical structure comprised in the region, using the region as a seed for determining the segment; wherein the definition of the two regions in the image is characterized in that the regions are placed directly either side of and abutting up to the indicated line on their respective sides. a memory comprising instruction data representing a set of instructions; a processor configured to communicate with the memory and to execute the set of instructions, wherein the set of instructions, when executed by the processor, cause the processor to: receive a first user input indicating a line in the image; define two regions in the image, one on either side of the indicated line, each region a butting the indicated line on its respective side; and for each of the two regions: determine a segment corresponding to an anatomical structure comprised in the region, using the region as a seed for determining the segment; wherein the definition of the two regions in the image is characterized in that the regions are placed directly either side of and abutting up to the indicated line on their respective sides. receive a first user input indicating a line in the image; define two regions in the image, one on either side of the indicated line, each region a butting the indicated line on its respective side; and for each of the two regions: determine a segment corresponding to an anatomical structure comprised in the region, using the region as a seed for determining the segment; wherein the definition of the two regions in the image is characterized in that the regions are placed directly either side of and abutting up to the indicated line on their respective sides. determine a segment corresponding to an anatomical structure comprised in the region, using the region as a seed for determining the segment; wherein the definition of the two regions in the image is characterized in that the regions are placed directly either side of and abutting up to the indicated line on their respective sides.
A method for milking an animal using a milking machine, wherein said milking machine comprises at least a first teat cup, said first teat cup comprises a teat cup liner and a teat cup shell, said teat cup liner comprises a lower end connected to a milking vacuum source for drawing milk from said milking animal, and a top end forming a space and a teat entrance in which a teat of a milking animal is to be introduced, said teat cup liner further comprises an inlet to said space connected to a source, said method is characterised by the step of: - setting (303; 404; 502) the vacuum level (P 2) in said space so that the vacuum difference between the vacuum level (P 3) in said lower end and the vacuum level (P 2) in said space is related to a parameter relating to the milking process of drawing milk from the milking animal being milked so that the milking speed for the teat of the milking animal can be controlled. - setting (303; 404; 502) the vacuum level (P 2) in said space so that the vacuum difference between the vacuum level (P 3) in said lower end and the vacuum level (P 2) in said space is related to a parameter relating to the milking process of drawing milk from the milking animal being milked so that the milking speed for the teat of the milking animal can be controlled.
A protection method for protecting an electronic device (SCARD), when the electronic device implements a cryptographic algorithm, against side channel attacks, the cryptographic algorithm working with a state array (MAT1, MAT2, MAT3), the cryptographic algorithm being designed to generate (SHFT_R), from a current state array, a second state array in which each row is obtained by shifting the corresponding row of the current state array, then to generate (MIX_C), from the second state array, a third state array in which the elements of each column are the result of mixing elements of the corresponding column of the second state array, the method being characterized in that it comprises replacing said two consecutive generations (SHFT_R, MIX_C) of the respective second and third state array (MAT2, MAT3) by a secure generation (SEC_GEN), from the current state array, of a state array equal to the third state array, this secure generation (SEC_GEN) mixing, in a randomized manner, the elements of the current state array that would have been located in a same column of the second state array if said second state array had been generated, in order to produce the corresponding column of the generated state array.
A method of geotagging an audio-recording, comprising: determining a location at which the audio-recording was recorded; obtaining an image containing an indication of the location; and creating (215, 240) a single file containing: the audio-recording; and the image, wherein the indication of the location comprises at least one of: a map that includes the location; an aerial or satellite photograph that includes the location; and text overlaid on the image to specify the location, and wherein the file is an MP3 file and the image is embedded as a JPEG or PNG file in an Attached Picture frame according to the ID3v2 specification. determining a location at which the audio-recording was recorded; obtaining an image containing an indication of the location; and creating (215, 240) a single file containing: the audio-recording; and the image, the audio-recording; and the image, wherein the indication of the location comprises at least one of: a map that includes the location; an aerial or satellite photograph that includes the location; and text overlaid on the image to specify the location, and wherein the file is an MP3 file and the image is embedded as a JPEG or PNG file in an Attached Picture frame according to the ID3v2 specification.
A tyre for a wheel of a heavy load vehicle, comprising: • a carcass structure comprising at least one carcass ply; • a belt structure applied in a radially outer position relative to said carcass structure; and • a tread band applied in a radially outer position relative to said carcass structure; wherein said belt structure comprises at least one reinforcing strip incorporating a plurality of reinforcing elements laid substantially in the circumferential direction; wherein said reinforcing elements comprise at least one high-elongation metal cord; wherein said metal cord comprises a plurality of twisted strands, each strand comprising a central filament and a plurality of outer filaments (203a,..., 203f) arranged to form a single circular outer ring around said central filament; wherein said metal cord comprises a number of strands not greater than three; wherein said central filament has a diameter greater than the diameter of the outer filaments (203a,..., 203f); characterized in that i. said metal cord has an elongation at break of at least 3.5%; ii. said belt structure comprises at least two radially superposed main belt layers (105a, 105b) incorporating a plurality of reinforcing elements that are substantially parallel to each other in each layer, inclined with respect to the circumferential direction of the tyre and oriented in such a way as to intersect each other with respect to the reinforcing elements of the adjacent layer, wherein said at least one reinforcing strip is arranged in a position radially external to said at least two main belt layers (105a, 105b); iii. said at least one reinforcing strip is arranged at a respective axially outer end of the radially outermost layer of said at least two main belt layers (105a, 105b); and iv. said belt structure comprises a third belt layer applied as a radially outermost layer of the belt structure and having reinforcing elements which are laid parallel to each other. • a carcass structure comprising at least one carcass ply; • a belt structure applied in a radially outer position relative to said carcass structure; and • a tread band applied in a radially outer position relative to said carcass structure; i. said metal cord has an elongation at break of at least 3.5%; ii. said belt structure comprises at least two radially superposed main belt layers (105a, 105b) incorporating a plurality of reinforcing elements that are substantially parallel to each other in each layer, inclined with respect to the circumferential direction of the tyre and oriented in such a way as to intersect each other with respect to the reinforcing elements of the adjacent layer, wherein said at least one reinforcing strip is arranged in a position radially external to said at least two main belt layers (105a, 105b); iii. said at least one reinforcing strip is arranged at a respective axially outer end of the radially outermost layer of said at least two main belt layers (105a, 105b); and iv. said belt structure comprises a third belt layer applied as a radially outermost layer of the belt structure and having reinforcing elements which are laid parallel to each other.
Method for treatment of aqueous organic waste, especially sewage sludge, from a wastewater treatment plant comprising the stages of - anaerobically digesting the waste in a first stage, - disintegrating digested waste from the first stage by cell wall destruction and - anaerobically digesting disintegrated waste in a second stage different from the first stage, characterized in that - after disintegrating digested waste and before digesting disintegrated waste in the second stage the disintegrated waste undergoes a liquid-solid-separation in a thickening stage, - whereas the thickened sludge from the thickening stage is fed to the second stage - and whereas part of the liquid phase separated in the thickening stage is fed back to the wastewater treatment plant. - anaerobically digesting the waste in a first stage, - disintegrating digested waste from the first stage by cell wall destruction and - anaerobically digesting disintegrated waste in a second stage different from the first stage, characterized in that - after disintegrating digested waste and before digesting disintegrated waste in the second stage the disintegrated waste undergoes a liquid-solid-separation in a thickening stage, - whereas the thickened sludge from the thickening stage is fed to the second stage - and whereas part of the liquid phase separated in the thickening stage is fed back to the wastewater treatment plant.
Plant container made from plastic material comprising a preferably closed bottom and comprising a side wall, which is connected to the bottom and has an openable water overflow opening, characterized in that the side wall has a film section at least in the area of the water overflow opening, said area being back-injection molded while leaving the water overflow opening free, and, at least at the lower edge of the water overflow opening facing the bottom, the ratio of the wall thickness of the back-injection molded area close to the edge to the film thickness is at least 2.5.
A compound of Formula for use in treating or inhibiting the progression of a PPAR-delta mediated condition: wherein X is selected from a covalent bond, S, and O; Y is S or O; Z is O or CH 2, provided when Y is O, then Z is O; R 1 and R 2 are independently selected from H, C 1-3 alkyl, C 1-3 alkoxy, halo, and NR a R b wherein R a and R b are independently H or C 1-3 alkyl; R 3 and R 4 are independently selected from H, halo, cyano, C 1-5 alkyl, hydroxy,C 2-4 acyl, C 1-4 alkoxy, and NR c R d wherein R c and R d are independently H or C 1-3 alkyl, provided that R 3 and R 4 are not both H; R 5 and R 6 are independently selected from halo, phenyl, C 1-9 alkyl, C 1-8 alkoxy, C 2-9 alkenyl, C 2-9 alkenyloxy, C 3-7 cycloalkyl, C 3-7 cycloalkoxy, C 3-7 cycloalkyl-C 1-7 alkyl, C 3-7 cycloalkyl-C 1-7 alkoxy, C 3-7 cycloalkyloxy-C 1-6 alkyl, and C 3-7 cycloalkyloxy-C 1-7 alkoxy, or R 5 and R 6 together form C 1-9 alkylidenyl or C 3-9 alkenylidenyl;or R 5, R 6 and the carbon atom to which they are attached together form C 3-7 cycloalkyl or 5- or 6-membered heterocyclyl; n is 0, 1 or 2; and m is 0, 1 or 2; or a pharmaceutically acceptable salt thereof. X is selected from a covalent bond, S, and O; Y is S or O; Z is O or CH 2, provided when Y is O, then Z is O; R 1 and R 2 are independently selected from H, C 1-3 alkyl, C 1-3 alkoxy, halo, and NR a R b wherein R a and R b are independently H or C 1-3 alkyl; R 3 and R 4 are independently selected from H, halo, cyano, C 1-5 alkyl, hydroxy,C 2-4 acyl, C 1-4 alkoxy, and NR c R d wherein R c and R d are independently H or C 1-3 alkyl, provided that R 3 and R 4 are not both H; R 5 and R 6 are independently selected from halo, phenyl, C 1-9 alkyl, C 1-8 alkoxy, C 2-9 alkenyl, C 2-9 alkenyloxy, C 3-7 cycloalkyl, C 3-7 cycloalkoxy, C 3-7 cycloalkyl-C 1-7 alkyl, C 3-7 cycloalkyl-C 1-7 alkoxy, C 3-7 cycloalkyloxy-C 1-6 alkyl, and C 3-7 cycloalkyloxy-C 1-7 alkoxy, or R 5 and R 6 together form C 1-9 alkylidenyl or C 3-9 alkenylidenyl;or R 5, R 6 and the carbon atom to which they are attached together form C 3-7 cycloalkyl or 5- or 6-membered heterocyclyl; n is 0, 1 or 2; and m is 0, 1 or 2; or a pharmaceutically acceptable salt thereof.
An apparatus comprising: (a) an instrument body (60, 410); (b) an elongated transmission assembly extending distally from the instrument body; (c) an end effector (80,412) located on the distal end of transmission assembly, wherein the end effector is operable to perform a surgical operation at a surgical site, wherein the end effector is further operable to deliver nerve excitation energy to tissue at the surgical site; (d) a control module in communication with the end effector, wherein the control module is operable to drive the end effector to deliver surgical energy to the surgical site, wherein the control module is further operable to drive the end effector to deliver nerve excitation energy to the surgical site, (e) a sensor in communication with the control module, wherein the sensor is configured to detect excitation of nervous tissue based on excitation caused by the nerve excitation energy, and f) a visual indicator incorporated into end effector (80,412) and in communication with the sensor, wherein the visual indicator is configured to convey whether the sensor detects a biological response to the nerve excitation energy. (a) an instrument body (60, 410); (b) an elongated transmission assembly extending distally from the instrument body; (c) an end effector (80,412) located on the distal end of transmission assembly, wherein the end effector is operable to perform a surgical operation at a surgical site, wherein the end effector is further operable to deliver nerve excitation energy to tissue at the surgical site; (d) a control module in communication with the end effector, wherein the control module is operable to drive the end effector to deliver surgical energy to the surgical site, wherein the control module is further operable to drive the end effector to deliver nerve excitation energy to the surgical site, (e) a sensor in communication with the control module, wherein the sensor is configured to detect excitation of nervous tissue based on excitation caused by the nerve excitation energy, and f) a visual indicator incorporated into end effector (80,412) and in communication with the sensor, wherein the visual indicator is configured to convey whether the sensor detects a biological response to the nerve excitation energy.
A redundant power supply system (10,11,12) for wind turbine control systems, said power supply system (10,11,12) being adapted to supply power to one or more power consumers of a wind turbine control system, the redundant power supply system comprising - the one or more power consumers, - a first power rail, - a second power rail, and wherein each of the one or more power consumers of the wind turbine control system comprises integrated switching means (331,332,333,334,33n,33,43a,43b) being adapted to select between the first and the second power rails (PR1,PR2) so as to provide power to at least part of a power consumer of the wind turbine control system from either the first power rail or the second power rail (PR1,PR2). - the one or more power consumers, - a first power rail, - a second power rail, and
A suspension device comprising: a wheel supporting member configured to rotatably support a wheel; two links (4, 5) respectively linking the wheel supporting member and a vehicle-body side member 3 and disposed substantially in parallel in a vehicle width direction; a projecting portion extending from a first of the two links positioned further backward in a vehicle forward-backward direction towards a second of the two links; two or more elastic linking portions (20, 21) disposed apart from each other in the vehicle width direction and linking the projecting portion of the two links; and a toe angle adjusting device (20d, 21 d) configured to input a force in a direction oriented backward in the vehicle forward-backward direction to the wheel supporting member to adjust a toe angle of the wheel, wherein the anisotropic properties of the rigidities of the two elastic portions (20, 21) are different from each other. a wheel supporting member configured to rotatably support a wheel; two links (4, 5) respectively linking the wheel supporting member and a vehicle-body side member 3 and disposed substantially in parallel in a vehicle width direction; a projecting portion extending from a first of the two links positioned further backward in a vehicle forward-backward direction towards a second of the two links; two or more elastic linking portions (20, 21) disposed apart from each other in the vehicle width direction and linking the projecting portion of the two links; and a toe angle adjusting device (20d, 21 d) configured to input a force in a direction oriented backward in the vehicle forward-backward direction to the wheel supporting member to adjust a toe angle of the wheel, wherein the anisotropic properties of the rigidities of the two elastic portions (20, 21) are different from each other.
An adapter collection ring structure, which includes a plurality of adapters, used to be connected to connectors of various different specifications; a ring shape lock piece, formed by a flexible wire body having a lock head and a lock insertion rod disposed at both ends respectively; a plurality of plug sleeve pieces, each having a fix end and a movable end, with the fix end connected to the wire body of the ring shape lock piece, and with its movable end connected to a connection portion, connected to the plurality of adapters respectively, wherein each plug sleeve piece is a flexible short section wire body, with a sleeve ring disposed at a tail portion of the fixed end of the plug sleeve piece, and a plurality of connection hole seats are disposed around and spaced equally apart along the ring shape lock piece; each of connection hole seats is provided with a hole sleeve body, and a plate having a hole (255, 357) is connected to the hole sleeve body; the hole sleeve body is for the ring shape lock piece to run through, and the plate having the hole (255, 357) is for the sleeve ring at the fixed end of the plug sleeve piece to run through a hole in the plate having the hole (255, 357). a plurality of adapters, used to be connected to connectors of various different specifications; a ring shape lock piece, formed by a flexible wire body having a lock head and a lock insertion rod disposed at both ends respectively; a plurality of plug sleeve pieces, each having a fix end and a movable end, with the fix end connected to the wire body of the ring shape lock piece, and with its movable end connected to a connection portion, connected to the plurality of adapters respectively, wherein each plug sleeve piece is a flexible short section wire body, with a sleeve ring disposed at a tail portion of the fixed end of the plug sleeve piece, and a plurality of connection hole seats are disposed around and spaced equally apart along the ring shape lock piece; each of connection hole seats is provided with a hole sleeve body, and a plate having a hole (255, 357) is connected to the hole sleeve body; the hole sleeve body is for the ring shape lock piece to run through, and the plate having the hole (255, 357) is for the sleeve ring at the fixed end of the plug sleeve piece to run through a hole in the plate having the hole (255, 357).
A wind turbine, comprising: a tower having an interior, an exterior, a lower end, and an upper end; a nacelle coupled to the tower adjacent the upper end thereof and movable relative to the tower to define at least two yaw positions of the nacelle; a rotor coupled to the nacelle and including a hub and at least one blade extending therefrom, the rotor configured to interact with the wind to rotate the rotor; and an access apparatus disposed about the tower adjacent the upper end thereof, the access apparatus defining a passageway into the nacelle that is exterior of the tower, and the access apparatus providing access to the nacelle in the at least two yaw positions of the nacelle; characterized in that the access apparatus further comprises: a housing having a bottom wall and at least one sidewall that defines a housing interior, the passageway providing communication between the interior of the housing and an interior of the nacelle. a tower having an interior, an exterior, a lower end, and an upper end; a nacelle coupled to the tower adjacent the upper end thereof and movable relative to the tower to define at least two yaw positions of the nacelle; a rotor coupled to the nacelle and including a hub and at least one blade extending therefrom, the rotor configured to interact with the wind to rotate the rotor; and an access apparatus disposed about the tower adjacent the upper end thereof, the access apparatus defining a passageway into the nacelle that is exterior of the tower, and the access apparatus providing access to the nacelle in the at least two yaw positions of the nacelle; characterized in that the access apparatus further comprises: a housing having a bottom wall and at least one sidewall that defines a housing interior, the passageway providing communication between the interior of the housing and an interior of the nacelle. a housing having a bottom wall and at least one sidewall that defines a housing interior, the passageway providing communication between the interior of the housing and an interior of the nacelle.