mhurhangee/ep-ind-claims huggingface dataset:
A cosmetic method for treating skin comprising topically applying to skin in need of treatment a topical skin composition comprising: (a) an effective amount of a Centella asiatica stem cells to reduce the activity of hyaluronidase in skin; (b) an effective amount of tetradecyl aminobutyroylvalylamino butyric urea trifluoroacetate to promote the production of hyaluronic acid in skin; (c) an effective amount of tripeptide-1 to promote the production of fibronectin and laminin in skin; and (d) a dermatologically acceptable vehicle, wherein topical application of the composition reduces the activity of hyaluronidase in skin, increases the production of hyaluronic acid in skin, and increases the production of fibronectin and laminin in skin. (a) an effective amount of a Centella asiatica stem cells to reduce the activity of hyaluronidase in skin; (b) an effective amount of tetradecyl aminobutyroylvalylamino butyric urea trifluoroacetate to promote the production of hyaluronic acid in skin; (c) an effective amount of tripeptide-1 to promote the production of fibronectin and laminin in skin; and (d) a dermatologically acceptable vehicle,
A spinal correction system comprising: a flexible longitudinal element extending between a first end and a second end; at least one fixation element including a first portion and a second portion, the first and second portions (12, 14) being provided as one piece, the first portion including an inner surface that defines a cavity such that the longitudinal element is disposable therein, the second portion being configured for penetrating tissue; a coupling member engageable with the first portion of the at least one fixation element and the longitudinal element to connect the longitudinal element with the at least one fixation element, the coupling member including a penetrating element configured to extend through the longitudinal element; characterized in that the spinal correction system further comprises a flexible member disposed between the longitudinal element and the inner surface of the first portion of the at least one fixation element, wherein the flexible member is disposed to bias the longitudinal element relative to the inner surface to maintain the connection of the longitudinal element with the at least one fixation element, wherein the flexible member is configured to adapt forces and/or force changes, including patient growth and degeneration, applied to the spinal correction system; and a washer disposed between the longitudinal element and the flexible member, wherein the penetrating element is configured to extend through the washer, wherein the longitudinal element includes a tether or a cadaver tendon. a flexible longitudinal element extending between a first end and a second end; at least one fixation element including a first portion and a second portion, the first and second portions (12, 14) being provided as one piece, the first portion including an inner surface that defines a cavity such that the longitudinal element is disposable therein, the second portion being configured for penetrating tissue; a coupling member engageable with the first portion of the at least one fixation element and the longitudinal element to connect the longitudinal element with the at least one fixation element, the coupling member including a penetrating element configured to extend through the longitudinal element; characterized in that the spinal correction system further comprises a flexible member disposed between the longitudinal element and the inner surface of the first portion of the at least one fixation element, wherein the flexible member is disposed to bias the longitudinal element relative to the inner surface to maintain the connection of the longitudinal element with the at least one fixation element, wherein the flexible member is configured to adapt forces and/or force changes, including patient growth and degeneration, applied to the spinal correction system; and a washer disposed between the longitudinal element and the flexible member, wherein the penetrating element is configured to extend through the washer, wherein the longitudinal element includes a tether or a cadaver tendon.
A method of manufacturing an aircraft interior panel comprising a core (22; 32) sandwiched between first (24; 34) and second (26; 36) skins, wherein both of the first and second skins are formed from natural fibres containing fire-retardant and set within an inorganic thermoset resin, thereby forming a fire-resistant sustainable aircraft interior panel, the method comprising: (a) impregnating the natural fibres with fire retardant to form fire-resistant natural fibres; (b) impregnating the fire-resistant natural fibres with inorganic thermoset resin; (c) laying up the resin-impregnated natural fibres to sandwich the core thereby forming a stack of the core sandwiched between the resin-impregnated natural fibres; and (d) curing the stack to form the fire resistant sustainable aircraft interior panel that comprises the core sandwiched between the first and second skins, characterized in that the curing step comprises: raising the temperature of the stack to a first temperature that is equal to or greater than a minimum activation temperature of the inorganic thermoset resin that initiates the curing reaction and less than the boiling point of water in the stack; holding the stack at the first temperature; raising the temperature of the stack to a second temperature that is equal to or greater than the boiling point of water in the stack; and cooling the stack to reduce the temperature of the stack from the second temperature. (a) impregnating the natural fibres with fire retardant to form fire-resistant natural fibres; (b) impregnating the fire-resistant natural fibres with inorganic thermoset resin; (c) laying up the resin-impregnated natural fibres to sandwich the core thereby forming a stack of the core sandwiched between the resin-impregnated natural fibres; and (d) curing the stack to form the fire resistant sustainable aircraft interior panel that comprises the core sandwiched between the first and second skins, characterized in that the curing step comprises: raising the temperature of the stack to a first temperature that is equal to or greater than a minimum activation temperature of the inorganic thermoset resin that initiates the curing reaction and less than the boiling point of water in the stack; holding the stack at the first temperature; raising the temperature of the stack to a second temperature that is equal to or greater than the boiling point of water in the stack; and cooling the stack to reduce the temperature of the stack from the second temperature. raising the temperature of the stack to a first temperature that is equal to or greater than a minimum activation temperature of the inorganic thermoset resin that initiates the curing reaction and less than the boiling point of water in the stack; holding the stack at the first temperature; raising the temperature of the stack to a second temperature that is equal to or greater than the boiling point of water in the stack; and cooling the stack to reduce the temperature of the stack from the second temperature.
A method for preparing a silica layer comprising a step of bringing a precursor layer formed of a precursor composition comprising a silica precursor, an acid catalyst and a surfactant to gelation, wherein the gelation is performed by contacting the precursor layer with an amine compound having a pKa of 8 or less, and wherein, as the amine compound, a compound represented by any one of the following formulas 1 to 4 is used: in Formulas 1 to 4, R 1 to R 15 is each independently an alkyl group, in Formula 2, R 6 and R 7 are each present in one or two or more, and when present in two or more, each of R 6 and R 7 are the same or different, and the alkyl group is a linear, branched or cyclic alkyl group having 1 to 20 carbon atoms. wherein the gelation is performed by contacting the precursor layer with an amine compound having a pKa of 8 or less, and wherein, as the amine compound, a compound represented by any one of the following formulas 1 to 4 is used: in Formulas 1 to 4, R 1 to R 15 is each independently an alkyl group, in Formula 2, R 6 and R 7 are each present in one or two or more, and when present in two or more, each of R 6 and R 7 are the same or different, and the alkyl group is a linear, branched or cyclic alkyl group having 1 to 20 carbon atoms.
A composition comprising: i) 1,1-difluoroethene (vinylidene fluoride, R-1132a); ii) trifluoromethane (R-23); and iii) 1% by weight to 45% by weight carbon dioxide (R-744, CO 2). i) 1,1-difluoroethene (vinylidene fluoride, R-1132a); ii) trifluoromethane (R-23); and iii) 1% by weight to 45% by weight carbon dioxide (R-744, CO 2).
A scalable method of proliferating cells from a human hepatocyte cell line, comprising: a) Seeding cells from a human hepatocyte cell line into an alginate matrix forming agent and forming alginate beads comprising matrix encapsulated cells; and b) Pre-culturing the matrix encapsulated cells, in a culture medium in a chamber having a fluidised bed, so that they form cohesive spheroids in a cell proliferation stage in which the matrix encapsulated cells are maintained in continuous suspension in the culture medium for 8 to 12 days, and grown to performance competence such that they maintain a near cuboidal cell architecture, have a close cell to cell and cell to matrix organisation and secrete extracellular matrix proteins and a repertoire of liver specific secreted proteins. a) Seeding cells from a human hepatocyte cell line into an alginate matrix forming agent and forming alginate beads comprising matrix encapsulated cells; and b) Pre-culturing the matrix encapsulated cells, in a culture medium in a chamber having a fluidised bed, so that they form cohesive spheroids in a cell proliferation stage in which the matrix encapsulated cells are maintained in continuous suspension in the culture medium for 8 to 12 days, and grown to performance competence such that they maintain a near cuboidal cell architecture, have a close cell to cell and cell to matrix organisation and secrete extracellular matrix proteins and a repertoire of liver specific secreted proteins.
Axle end assembly for a vehicle, having a wheel brake arrangement and a wheel hub arrangement, wherein the axle end assembly is in the form of a preassembled unit which has a hollow shaft element (2, 2'), on which the wheel brake arrangement and the wheel hub arrangement are arranged, wherein the preassembled unit can be mounted as a whole on an axle body of a vehicle axle, and the hollow shaft element (2, 2') is designed to be connected to a first end of the axle body, wherein the hollow shaft element (2, 2') has a threaded portion on the one axial end thereof, which portion is designed to be screwed together with a corresponding threaded portion of the axle body, wherein the wheel brake arrangement of the preassembled unit comprises at least one brake adapter designed in the manner of a mounting plate and extending substantially radially to the hollow shaft element (2, 2') or to the axial direction thereof for mounting a wheel brake, in particular a disc brake, characterised in that the brake adapter is penetrated by the hollow shaft element (2, 2') and in that a direct torque transmission interface is formed between the brake adapter and the axle body.
The crusher for grinding and crushing materials, especially residual and waste material resulting from metal working, comprising a frame with a hopper, at least one drive unit and a crushing and grinding assembly comprising at least two counter-driven screw rotors (5, 5'), where each of the screw rotors (5, 5') is provided with at least two screw blades (6, 6'), where on both the first screw rotor and the second screw rotor, is at least one pair of screw blades (6, 6'), which are arranged symmetrically to each other to the centre of the screw rotor (5, 5'), where one of the screw blades (6, 6') forms a right-hand thread and the other of the screw blades (6, 6') forms a left-hand thread, characterized in that the left-hand screw blade on the second screw rotor is assigned to the right-hand screw blade on the first screw rotor and the right-hand screw blade on the second screw rotor is assigned to the left-hand screw blade on the first screw rotor, where the outer edges of the screw blades (6, 6') on the first screw rotor and the second screw rotor skew to each other when the screw rotors (5, 5') are rotated, with an overlap on the projection in the horizontal plane, and recesses corresponding to the shape of the separation bars mounted on the surface of the screw rotors (5, 5') parallel to the axis of their rotation are formed on the screw blades (6, 6') and positioned such that when rotating the screw rotors (5, 5'), the separation bars on the first screw rotor are associated with the recesses of the screw blades (6, 6') on the second screw rotor and the separation bars on the second screw rotor are associated with the recesses of the screw blades (6, 6') on the first screw rotor.
A prosthetic heart valve (100; 200; 400; 500; 700), comprising: a frame (102; 402; 502) comprising a plurality of strut members (104; 404; 504) and having an inflow end (106; 406; 508) and an outflow end (108; 408; 510), a leaflet structure situated at least partially within the frame (102; 402; 502), and a covering (112; 202; 412; 514; 700) disposed around the frame (102; 402; 502), the covering (112; 202; 412; 514; 700) comprising: a cushioning layer (116; 208; 414; 516; 702) having a plush surface, an inflow protective portion (120; 416; 518; 706) folded over a circumferential inflow edge portion of the cushioning layer (116; 208; 414; 516; 702) so as to cover apices (124; 420; 506) of the strut members (104; 404; 504) at the inflow end (106; 406; 508) of the frame (102; 402; 502), and optionally an outflow protective portion (122; 418; 520; 708) folded over a a circumferential outflow edge portion of the cushioning layer (116; 208; 414; 516; 702) so as to cover apices (124; 420; 506) of the strut members (104; 404; 504) at the outflow end (108; 408; 510) of the frame (102; 402; 502). a frame (102; 402; 502) comprising a plurality of strut members (104; 404; 504) and having an inflow end (106; 406; 508) and an outflow end (108; 408; 510), a leaflet structure situated at least partially within the frame (102; 402; 502), and a covering (112; 202; 412; 514; 700) disposed around the frame (102; 402; 502), the covering (112; 202; 412; 514; 700) comprising: a cushioning layer (116; 208; 414; 516; 702) having a plush surface, an inflow protective portion (120; 416; 518; 706) folded over a circumferential inflow edge portion of the cushioning layer (116; 208; 414; 516; 702) so as to cover apices (124; 420; 506) of the strut members (104; 404; 504) at the inflow end (106; 406; 508) of the frame (102; 402; 502), and optionally an outflow protective portion (122; 418; 520; 708) folded over a a circumferential outflow edge portion of the cushioning layer (116; 208; 414; 516; 702) so as to cover apices (124; 420; 506) of the strut members (104; 404; 504) at the outflow end (108; 408; 510) of the frame (102; 402; 502). a cushioning layer (116; 208; 414; 516; 702) having a plush surface, an inflow protective portion (120; 416; 518; 706) folded over a circumferential inflow edge portion of the cushioning layer (116; 208; 414; 516; 702) so as to cover apices (124; 420; 506) of the strut members (104; 404; 504) at the inflow end (106; 406; 508) of the frame (102; 402; 502), and optionally an outflow protective portion (122; 418; 520; 708) folded over a a circumferential outflow edge portion of the cushioning layer (116; 208; 414; 516; 702) so as to cover apices (124; 420; 506) of the strut members (104; 404; 504) at the outflow end (108; 408; 510) of the frame (102; 402; 502).
Device for transmitting sounds for intra-auricular earpiece, comprising an entrance opening extending along an entrance axis, said entrance opening being able to receive a sound emission source, an exit opening able to be presented in an ear and a diffusion enclosure able to conduct the sound from upstream to downstream from said entrance opening to said exit opening, device characterised by the fact that said diffusion enclosure comprises, opposite said entrance opening, a first vibration wall extending orthogonally to the entrance axis able to resonate following a sound emission along said entrance axis, the diffusion enclosure comprising at least one upper core in contact with the first vibration wall in order to stretch it.
A rotary electric machine comprising: a stator extending along an axis and having a circumferentially spaced series of axially extending teeth defining a similar series of circumferentially spaced winding slots therebetween, a plurality of stator windings (2, 3) at least partially disposed respectively in the slots, said windings (2, 3) being electrically connected to form a plurality of phases such that one or more winding slots contain the same magnitude of current at substantially all times for each phase; and structure defining a plurality of elongated coolant passageways (9, 10, 11, 12) disposed in each winding slot, wherein none of the coolant passageways (9, 10, 11, 12) in different winding slots are fluidly connected in series with one another; wherein a subset of the coolant passageways (9, 10, 11, 12) contained in the slots for a single phase having an even number with coolant flowing in one direction for half of the subset of coolant passageways (9, 10, 11, 12) and in the opposite direction for the other half of the subset of coolant passageways (9, 10, 11, 12); wherein at least one of the coolant passageways (9, 10, 11, 12) is located circumferentially between two windings (2, 3) in the same slot. a stator extending along an axis and having a circumferentially spaced series of axially extending teeth defining a similar series of circumferentially spaced winding slots therebetween, a plurality of stator windings (2, 3) at least partially disposed respectively in the slots, said windings (2, 3) being electrically connected to form a plurality of phases such that one or more winding slots contain the same magnitude of current at substantially all times for each phase; and structure defining a plurality of elongated coolant passageways (9, 10, 11, 12) disposed in each winding slot, wherein none of the coolant passageways (9, 10, 11, 12) in different winding slots are fluidly connected in series with one another; wherein a subset of the coolant passageways (9, 10, 11, 12) contained in the slots for a single phase having an even number with coolant flowing in one direction for half of the subset of coolant passageways (9, 10, 11, 12) and in the opposite direction for the other half of the subset of coolant passageways (9, 10, 11, 12); wherein at least one of the coolant passageways (9, 10, 11, 12) is located circumferentially between two windings (2, 3) in the same slot.
A curable resin composition comprising: a) 5 to 99 wt. % of a block copolymer, wherein the block copolymer contains at least an A block and at least one of B, B', and C block; wherein each A block is a non hydrogenated poly(acyclic conjugated diene) polymer comprising polymerized units of at least one acyclic conjugated diene; each B block is a poly(1,3-cyclodiene) homopolymer with GPC block Mp of < 25kg/mol, each B' block is a poly(1,3-cyclodiene-co-monoalkenyl arene) copolymer with GPC block Mp of < 30kg/mol each C block is a poly(alkenyl arene) polymer or copolymer containing at least one high Tg alkenyl arene unit having a Tg of > 100°C, as measured in the description, and the block copolymer has a GPC peak molecular weight Mp of < 50 kg/mol before coupling; the block copolymer has a GPC peak molecular weight Mp multiplied by the A block content weight fraction of > 500g/mol; b) from 0.1 to 10 wt. % of a cure initiator; and c) up to 95 wt.% of one or more additives selected from a multi-functional co-curable additive, a diene based rubber, a halogenated or non halogenated flame retardant, an inorganic or organic filler or fiber, an antioxidant, a adhesion promotor, and a film forming polymer. a) 5 to 99 wt. % of a block copolymer, wherein the block copolymer contains at least an A block and at least one of B, B', and C block; wherein each A block is a non hydrogenated poly(acyclic conjugated diene) polymer comprising polymerized units of at least one acyclic conjugated diene; each B block is a poly(1,3-cyclodiene) homopolymer with GPC block Mp of < 25kg/mol, each B' block is a poly(1,3-cyclodiene-co-monoalkenyl arene) copolymer with GPC block Mp of < 30kg/mol each C block is a poly(alkenyl arene) polymer or copolymer containing at least one high Tg alkenyl arene unit having a Tg of > 100°C, as measured in the description, and the block copolymer has a GPC peak molecular weight Mp of < 50 kg/mol before coupling; the block copolymer has a GPC peak molecular weight Mp multiplied by the A block content weight fraction of > 500g/mol; wherein each A block is a non hydrogenated poly(acyclic conjugated diene) polymer comprising polymerized units of at least one acyclic conjugated diene; each B block is a poly(1,3-cyclodiene) homopolymer with GPC block Mp of < 25kg/mol, each B' block is a poly(1,3-cyclodiene-co-monoalkenyl arene) copolymer with GPC block Mp of < 30kg/mol each C block is a poly(alkenyl arene) polymer or copolymer containing at least one high Tg alkenyl arene unit having a Tg of > 100°C, as measured in the description, and the block copolymer has a GPC peak molecular weight Mp of < 50 kg/mol before coupling; the block copolymer has a GPC peak molecular weight Mp multiplied by the A block content weight fraction of > 500g/mol; b) from 0.1 to 10 wt. % of a cure initiator; and c) up to 95 wt.% of one or more additives selected from a multi-functional co-curable additive, a diene based rubber, a halogenated or non halogenated flame retardant, an inorganic or organic filler or fiber, an antioxidant, a adhesion promotor, and a film forming polymer.
Latch assembly for an automotive vehicle with at least one first element and a second element, one element being mobile to the other one, comprising: - a latch intended to be fixed in the first element, - a striker with at least one wire and intended to be fixed in the second element, the latch being able to maintain the striker, the latch further comprising a claw adapted to receive the wire by rotating around the wire according to a first axis and having at least one recess in a convex shape disposed in the body of the latch facing the said wire, the said recess having a first end and a second end, a length of a segment between the first end and the second end being superior to the diameter (d) of the wire facing the recess. - a latch intended to be fixed in the first element, - a striker with at least one wire and intended to be fixed in the second element, the latch being able to maintain the striker,