mhurhangee/ep-ind-claims huggingface dataset:
Process for opening of thread ends for a splicer with the steps: (i) The thread is cut to length by a cutting device of the splicer, whereby the thread is situated in the feed section of a holding and opening tube of the splicer, (ii) at the latest after the thread is cut to length a suction flow is generated at the holding and opening tube, (ii.A) the thread end is transported to the feed area of the holding and opening tube by retracting the thread with a thread retraction device while the thread is also held in the feed area of the holding and opening tube by the attached suction flow, (iii) the end of the thread is sucked into the holding and opening tube by the suction flow attached to the holding and opening tube, (iv) the thread end is opened by a dissolving flow which is now at the latest attached in the holding and opening tube, characterised in that the thread retraction device in step (ii.A) positioning the thread end in the feed area of the holding and opening tube, so that the suction flow at the holding and opening tube sucks the thread with the thread end forward into the holding and opening tube. (i) The thread is cut to length by a cutting device of the splicer, whereby the thread is situated in the feed section of a holding and opening tube of the splicer, (ii) at the latest after the thread is cut to length a suction flow is generated at the holding and opening tube, (ii.A) the thread end is transported to the feed area of the holding and opening tube by retracting the thread with a thread retraction device while the thread is also held in the feed area of the holding and opening tube by the attached suction flow, (iii) the end of the thread is sucked into the holding and opening tube by the suction flow attached to the holding and opening tube, (iv) the thread end is opened by a dissolving flow which is now at the latest attached in the holding and opening tube, characterised in that the thread retraction device in step (ii.A) positioning the thread end in the feed area of the holding and opening tube, so that the suction flow at the holding and opening tube sucks the thread with the thread end forward into the holding and opening tube.
An aminothiazole-based specific inhibitor of MyD88 (myeloid differentiation protein 88) for use in reducing rejections after an organ transplantation as an immunosuppressive agent and being represented by the following formulas: 1) TJ-M2010-1 2-(4-(4-methoxyphenyl)piperazin-1-yl)-N-(4-phenyl-thiazole-2-yl) acetamide 2) TJ-M2010-2 2-(4-(p-tolyl)piperazin-1-yl)-N-(4-phenyl-thiazole-2-yl)acetamide 3) TJ-M2010-3 2-(4-phenyl-piperazin-1-yl)-N-(4-phenyl-thiazole-2-yl)acetamide 4) TJ-M2010-4 3-(4-(4-methoxyphenyl)piperazin-1-yl)-N-(4-phenyl-thiazole-2-yl)-propionamide 1) TJ-M2010-1 2-(4-(4-methoxyphenyl)piperazin-1-yl)-N-(4-phenyl-thiazole-2-yl) acetamide 2) TJ-M2010-2 2-(4-(p-tolyl)piperazin-1-yl)-N-(4-phenyl-thiazole-2-yl)acetamide 3) TJ-M2010-3 2-(4-phenyl-piperazin-1-yl)-N-(4-phenyl-thiazole-2-yl)acetamide 4) TJ-M2010-4 3-(4-(4-methoxyphenyl)piperazin-1-yl)-N-(4-phenyl-thiazole-2-yl)-propionamide
Thread moulding screw with a thread (5, 9) formed of screw cores (4, 8) for fastening the screw to an attachment, wherein the thread, going out from the tip of the screw first comprises a thread-moulding section as a pre-thread section, with a main thread section connecting to said pre-thread section, wherein the flank height of the thread of the pre-thread section is smaller than that of the main thread located in the cylindrical part of the thread shaft, wherein the pre-thread section, related to its longitudinal extension, extends at least mainly in the cylindrical part of the screw shaft, and at least one chip pocket is located therein, characterised in that arranged in the pre-thread section, distributed over the circumference, are a plurality of chip pockets (T 1, T 2, T 3) introduced into the screw core, and, in consequence, the screw core exhibits, in the region of the chip pockets, a cross-section geometry which differs at least very largely from the cylindrical cross-section shape of the screw shaft, and, as a consequence of this cross-section geometry, the thread is formed, in the region of the chip pockets (T 1, T 2, T 3) in each case by individual thread segments (G 1, G 2, G 3) extending over a certain angle, and that the thread segments (G 1, G 2, G 3) in each case extend over an angle from 10 to 30°, in particular over some 20 to 25°, along the case surface.
A method for converting a conventional extruder into a foam extruder for producing a foamed extrudate from a polymer melt by means of a physical blowing fluid, the conventional extruder containing a plasticizing cylinder and a plasticizing screw which can be rotated therein, wherein the polymer melt is generated in the plasticizing cylinder, wherein the plasticizing cylinder is extended by a tempered cylinder section, wherein the tempered cylinder section has an opening through which the physical blowing fluid is introduced into the polymer melt, wherein the physical blowing fluid is mixed by means of an extended plasticizing screw into the polymer melt, the extended plasticizing screw being arranged in the interior of the tempered cylinder section, wherein the plasticizing screw is configured as a twin screw, wherein each of the extended plasticizing screws of the twin screw rotate with the corresponding rotatable plasticizing screw of the twin screw, wherein each of the extended plasticizing screws is provided with shear elements and mixing elements, such that the temperature-controlled cylinder section forms a mixing section for the polymer melt containing blowing agent, wherein the tempered cylinder section is smooth on the inside and the tempered cylinder section is flanged to the existing plasticizing cylinder.
An information providing method for a vehicle, comprising: stopping an engine automatically when a predetermined permission condition is satisfied in a state in which the vehicle is stopped by brake operation of a driver; characterised in that after elapse of a predetermined time following a vehicle stop, when the permission condition that a predetermined operation amount of brake is reached is not satisfied, notifying the driver support information for prompting to increase in the brake operation; operating a vehicle stop keeping control for generating a braking force capable of maintaining a vehicle stop state even when the brake operation decreases; and notifying the driver the support information, prior to elapse of the predetermined time, in a state in which the vehicle is stopped by the brake operation and the vehicle stop keeping control is in operation, in response to decrease in the brake operation. stopping an engine automatically when a predetermined permission condition is satisfied in a state in which the vehicle is stopped by brake operation of a driver; characterised in that after elapse of a predetermined time following a vehicle stop, when the permission condition that a predetermined operation amount of brake is reached is not satisfied, notifying the driver support information for prompting to increase in the brake operation; operating a vehicle stop keeping control for generating a braking force capable of maintaining a vehicle stop state even when the brake operation decreases; and notifying the driver the support information, prior to elapse of the predetermined time, in a state in which the vehicle is stopped by the brake operation and the vehicle stop keeping control is in operation, in response to decrease in the brake operation.
A sound wave treatment device for medical treatment using compression waves, in particular for lithotripsy, having: - a sound wave generator, - a plurality of piezo elements that are coupled to the sound wave generator, and, - an electrical high voltage unit that is set up for supplying the piezo elements with high electrical voltage characterized in that the high voltage unit has a blocking converter unit having a transformer, wherein the transformer has a primary coil (L 1), a high voltage coil (L 4), and spacers, wherein the high voltage coil (L 4) has a plurality of high voltage windings that are embedded in an insulating mass and are positioned using the spacers such that adjacent high voltage windings are at a defined distance (a) from one another due to the spacers. - a sound wave generator, - a plurality of piezo elements that are coupled to the sound wave generator, and, - an electrical high voltage unit that is set up for supplying the piezo elements with high electrical voltage
Glazing unit comprising a substrate having two opposing external faces (20, 21) and a peripheral edge face linking the two faces, as well as peripheral sealing means added at the border of the substrate against its edge face and its two external faces, the sealing means comprising at least two seals (3A, 3B) each cooperating respectively with one of the two external faces (20, 21) of the substrate, characterized in that each of said two seals further cooperates with the edge face of the substrate, the two seals forming a zone of overlap over one another on the edge face of the glazing unit.
A system, comprising: a load moving machine, comprising: a frame; and a movable assembly coupled to the frame, wherein the movable assembly comprises a lift portion, a rotational portion, a first translational portion, and a second translational portion; characterized in that: the movable assembly further comprises a spreader bar comprising one or more load couplings; wherein the spreader bar comprises a slot extending lengthwise along the spreader bar, the lift portion comprises a first stabilizing guide (123, 125) disposed in the slot, and the lift portion comprises second (123, 126) and third (123, 127) stabilizing guides disposed outside of the slot on opposite sides of the spreader bar. a frame; and a movable assembly coupled to the frame, wherein the movable assembly comprises a lift portion, a rotational portion, a first translational portion, and a second translational portion; characterized in that: the movable assembly further comprises a spreader bar comprising one or more load couplings; wherein the spreader bar comprises a slot extending lengthwise along the spreader bar, the lift portion comprises a first stabilizing guide (123, 125) disposed in the slot, and the lift portion comprises second (123, 126) and third (123, 127) stabilizing guides disposed outside of the slot on opposite sides of the spreader bar. the movable assembly further comprises a spreader bar comprising one or more load couplings; wherein the spreader bar comprises a slot extending lengthwise along the spreader bar, the lift portion comprises a first stabilizing guide (123, 125) disposed in the slot, and the lift portion comprises second (123, 126) and third (123, 127) stabilizing guides disposed outside of the slot on opposite sides of the spreader bar.
Electrical switching device, in particular configured for a motor vehicle and comprising - a printed circuit board with a top side and a bottom side, wherein the printed circuit board extends in a longitudinal direction and in a transverse direction, - at least one electronic power switch which is fitted on the top side of the printed circuit board, as well as - a first busbar which extends in the longitudinal direction and is electrically-conductively connected to the at least one power switch, wherein - the first busbar is arranged on the top side of the printed circuit board and has a central region which runs above the at least one electronic power switch, and - the first busbar is thermally-conductively connected to the at least one power switch. characterized in that - a second busbar is arranged on the bottom side of the printed circuit board, which is also electrically-conductively connected to the at least one electronic power switch, and - the second busbar is also thermally-conductively connected to the at least one power switch. - a printed circuit board with a top side and a bottom side, wherein the printed circuit board extends in a longitudinal direction and in a transverse direction, - at least one electronic power switch which is fitted on the top side of the printed circuit board, as well as - a first busbar which extends in the longitudinal direction and is electrically-conductively connected to the at least one power switch, - the first busbar is arranged on the top side of the printed circuit board and has a central region which runs above the at least one electronic power switch, and - the first busbar is thermally-conductively connected to the at least one power switch. - a second busbar is arranged on the bottom side of the printed circuit board, which is also electrically-conductively connected to the at least one electronic power switch, and - the second busbar is also thermally-conductively connected to the at least one power switch.
Nozzle ring, comprising a first, annular plate-like fastening ring and a second, annular plate-like fastening ring and also a multiplicity of guide vanes which are arranged between the fastening rings (10, 11), which are arranged coaxially to each other, and are fixed in a respective angular position, characterized in that the guide vanes have in each case a pin on a first end face, in that the guide vanes are guided in a first fastening ring by means of the arrangement of the respective pin in a respective hole wherein the respective pin and the respective hole are formed in such a way that the guide vane, during the assembly of the nozzle ring, can be oriented into the respective angular position, in that the guide vanes, on a second end face, have in each case at least one positioning aid which corresponds in each case at least partially to the outer contour of said second end face, and in that the guide vanes are fixed with regard to their angular position by means of the arrangement of the at least one positioning aid in an opening in each case - which corresponds to the shape of the positioning aid - in the second fastening ring.
Tank for a drug infusion device, comprising a hollow cylindrical body provided at its front with an opening for the passage of the drug and in its inside with a plunger slidable within the tank for drawing in and/or injecting the drug through said opening, said tank being provided at its rear with a coupling part for ensuring the mechanical connection of the tank with a complementary coupling part provided in the infusion device, said coupling parts defining together a bayonet-like connection coupling, characterized in that said coupling part of the tank is housed inside the cylindrical body and comprises a female part associated with the tank and a male part associated with the infusion device, wherein the female part is associated with the tank and is provided with axial inlets formed in the wall of the cylindrical body at the base of said cylindrical body and radially open towards the inside of the tank and communicating with a corresponding number of radial grooves circumferentially extending between one axial inlet and another and having an interruption at the end opposite to the respective inlet for forming an abutment for the teeth of the male part of the bayonet-like connection coupling.
A method of producing a heavy chain-only antibody which binds specifically to an antigen comprising: (a) immunising a non-human transgenic mammal with the antigen, wherein the mammal expresses heavy chain-only antibodies which lack a CH1 domain in the transcribed and processed heavy chain mRNA, and wherein the heavy chain-only antibodies are expressed from a transgenic locus in the mammal; (b) isolating long-lived plasma cells or memory B-cells from the immunised mammal; (c) isolating an mRNA population from cells derived from step (b); (d) cloning a cDNA population derived from the mRNA isolated in step (c) into an expression vector and expressing the expression vector in a cell-line; and (e) selecting at least one cell-line which produces a heavy chain-only antibody which binds specifically to the antigen, wherein the mammal is a mouse or a rat. (a) immunising a non-human transgenic mammal with the antigen, wherein the mammal expresses heavy chain-only antibodies which lack a CH1 domain in the transcribed and processed heavy chain mRNA, and wherein the heavy chain-only antibodies are expressed from a transgenic locus in the mammal; (b) isolating long-lived plasma cells or memory B-cells from the immunised mammal; (c) isolating an mRNA population from cells derived from step (b); (d) cloning a cDNA population derived from the mRNA isolated in step (c) into an expression vector and expressing the expression vector in a cell-line; and (e) selecting at least one cell-line which produces a heavy chain-only antibody which binds specifically to the antigen, wherein the mammal is a mouse or a rat.
A method for detecting when a rotor blade of a wind turbine is stuck, the method comprising: monitoring, via a controller, a speed of rotation of the wind turbine; determining, via the controller, a running statistic of the speed of rotation; applying, via the controller, at least one filtering operation to the running statistic to obtain a filtered value, wherein the at least one filtering operation is based at least in part on a threshold of a coefficient of variance in the running statistic; determining, via the controller, a stuck condition of one or more rotor blades of the wind turbine based on the filtered value; and performing a control operation to reduce loading on the wind turbine based on the stuck condition. monitoring, via a controller, a speed of rotation of the wind turbine; determining, via the controller, a running statistic of the speed of rotation; applying, via the controller, at least one filtering operation to the running statistic to obtain a filtered value, wherein the at least one filtering operation is based at least in part on a threshold of a coefficient of variance in the running statistic; determining, via the controller, a stuck condition of one or more rotor blades of the wind turbine based on the filtered value; and performing a control operation to reduce loading on the wind turbine based on the stuck condition.
A heart valve system, the system comprising: a radially self-expandable tubular body having an inflow end and an outflow end; and a valve coupled to the tubular body, the valve including a plurality of valve leaflets, wherein: the valve is coupled to the outflow end of the tubular body such that the valve leaflets extend distally of the outflow end of the tubular body in an outflow direction, and the inflow end of the tubular body is connected to the outflow end of the tubular body at connection points, a number of connection points being equivalent to a number of the valve leaflets. a radially self-expandable tubular body having an inflow end and an outflow end; and a valve coupled to the tubular body, the valve including a plurality of valve leaflets, wherein: the valve is coupled to the outflow end of the tubular body such that the valve leaflets extend distally of the outflow end of the tubular body in an outflow direction, and the inflow end of the tubular body is connected to the outflow end of the tubular body at connection points, a number of connection points being equivalent to a number of the valve leaflets. the valve is coupled to the outflow end of the tubular body such that the valve leaflets extend distally of the outflow end of the tubular body in an outflow direction, and the inflow end of the tubular body is connected to the outflow end of the tubular body at connection points, a number of connection points being equivalent to a number of the valve leaflets.
A three-dimensional printer comprising: a delivery device to selectively deliver liquid droplets onto a layer of build materials; and a controller to determine a preselected area on the layer of build materials at which the delivery device is to deliver liquid droplets; to determine a distribution at which gaps are to be formed in the delivery of the liquid droplets within the preselected area, in which no liquid droplets are to be distributed; and to control the delivery device to deliver the liquid droplets across the preselected area while forming the gaps at the determined distribution, wherein the gaps are to form heat sinks in the build materials that are to prevent heat spikes from occurring across the build materials in the preselected area. a delivery device to selectively deliver liquid droplets onto a layer of build materials; and a controller to determine a preselected area on the layer of build materials at which the delivery device is to deliver liquid droplets; to determine a distribution at which gaps are to be formed in the delivery of the liquid droplets within the preselected area, in which no liquid droplets are to be distributed; and to control the delivery device to deliver the liquid droplets across the preselected area while forming the gaps at the determined distribution, wherein the gaps are to form heat sinks in the build materials that are to prevent heat spikes from occurring across the build materials in the preselected area.
An antioxidant agent adapted to be applied to the surface of a metallic starting material, containing: a plurality of glass frits having different softening points; and an inorganic compound having a melting point not higher than 600°C, wherein the inorganic compound is at least one of boric acid and boron oxide, and the plurality of glass frits contain high-temperature glass frits having a viscosity of 2 x 10 2 to 10 6 dPa·s at 1200°C and medium-temperature glass frits having a viscosity of 2 x 10 2 to 10 6 dPa·s at 700°C. a plurality of glass frits having different softening points; and an inorganic compound having a melting point not higher than 600°C, wherein the inorganic compound is at least one of boric acid and boron oxide, and the plurality of glass frits contain high-temperature glass frits having a viscosity of 2 x 10 2 to 10 6 dPa·s at 1200°C and medium-temperature glass frits having a viscosity of 2 x 10 2 to 10 6 dPa·s at 700°C.
N-{3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide, which is a compound of formula (Ia) or a pharmaceutically acceptable salt thereof.
A surgical instrument, comprising; an end effector; and first and second elongate shafts rotatably coupled such that rotation of one of the shafts causes opposite rotation of the other of the shafts, wherein the first and second elongate shafts are translatable between a first axial position and a second axial position, characterized in that: rotation of at least one of the shafts at the first axial position effects a clamping operation of the end effector and rotation of at least one of the shafts at the second axial position effects a stapling operation of the end effector, the elongate shafts being operatively connected with each other such that the elongate shafts are redundant, whereby only one elongate shaft is needed to operate the surgical instrument. rotation of at least one of the shafts at the first axial position effects a clamping operation of the end effector and rotation of at least one of the shafts at the second axial position effects a stapling operation of the end effector, the elongate shafts being operatively connected with each other such that the elongate shafts are redundant, whereby only one elongate shaft is needed to operate the surgical instrument.
Cam follower roller device, notably for fuel injection pump of an internal combustion engine, comprises a casing, a shaft mounted on the casing and a roller rotatably mounted on said shaft, characterized in that the casing comprises on its periphery at least four openings (26, 30) made through the thickness of the casing and located in such a way that two openings face one end of the outer cylindrical surface of the roller.