mhurhangee/ep-ind-claims huggingface dataset:
A method for producing an antigen comprising at least one hydrophobic or partially hydrophobic antigen molecule from a virus, a bacterium, fungus, protozoan, parasite, a human neoplastic cell or an animal neoplastic, tumour or cancer cell or an integral membrane or peripheral membrane protein from a eukaryotic cell, the method comprising the steps of - providing a virus, or cell comprising an antigen molecule, - wherein, when a cell is provided, purifying the cell comprising the antigen molecule, - solubilizing the antigen molecule in a solubilizing agent that preserves intact an antigen molecule upon solubilization, - reconstituting the antigen molecule in the presence of a lipid-binding polypeptide that provides a lipid membrane mimicking environment, wherein the solubilized antigen self-assembles into stable lipid binding polypeptide-antigen particles, and wherein the lipid-binding polypeptide that provides a lipid membrane mimicking environment is a saposin-like protein (SAPLIP) or a truncated form thereof, wherein - the SAPLIP is selected from (Homo sapiens, Equus caballus, Bos taurus, Mus musculus, Oryctolagus cuniculus, Rattus norvegicus or Xenopus laevis) saposin A, saposin B, saposin C or saposin D, and wherein - the truncated form thereof is amphipathic, forms at least one alpha helix, and is capable of self-assembling together with solubilized antigens into lipid-binding polypeptide/antigen particles when employed in the preparation method that is specified above. - providing a virus, or cell comprising an antigen molecule, - wherein, when a cell is provided, purifying the cell comprising the antigen molecule, - solubilizing the antigen molecule in a solubilizing agent that preserves intact an antigen molecule upon solubilization, - reconstituting the antigen molecule in the presence of a lipid-binding polypeptide that provides a lipid membrane mimicking environment, wherein the solubilized antigen self-assembles into stable lipid binding polypeptide-antigen particles, and - the SAPLIP is selected from (Homo sapiens, Equus caballus, Bos taurus, Mus musculus, Oryctolagus cuniculus, Rattus norvegicus or Xenopus laevis) saposin A, saposin B, saposin C or saposin D, and wherein - the truncated form thereof is amphipathic, forms at least one alpha helix, and is capable of self-assembling together with solubilized antigens into lipid-binding polypeptide/antigen particles when employed in the preparation method that is specified above.
A process for enriching an iron mineral from a silicate containing iron ore by inverse flotation comprising the addition of a collector or collector composition comprising at least one of the compounds of formulae RC N(Z-OX-NH 2) 2 (Ia); RC N(Z-O-X-NH 2) 2 H + Y - (Ib); in which X is an aliphatic alkylene group containing 2 to 6 carbon atoms; Z is an aliphatic alkylene group containing 2 to 6 carbon atoms; Y - is an anion; and R is a saturated or unsaturated, linear or branched, aliphatic or aromatic hydrocarbyl moiety having between 7 and 23 carbon atoms. X is an aliphatic alkylene group containing 2 to 6 carbon atoms; Z is an aliphatic alkylene group containing 2 to 6 carbon atoms; Y - is an anion; and R is a saturated or unsaturated, linear or branched, aliphatic or aromatic hydrocarbyl moiety having between 7 and 23 carbon atoms.
A sliding bushing comprising: a load bearing substrate, having a first major surface, a second major surface, and an edge, the load bearing substrate having a thickness t1, a metal containing layer (104; 1042) which is a corrosion protective layer and which is overlying and in direct contact with the first major surface, the metal containing layer (104; 1042) having a thickness t2, wherein the metal containing layer (104; 1042) contains a metal selected from magnesium, aluminum, titanium, scandium, zinc, or any combination thereof, a sliding layer overlying the first or the second major surface, characterized in that a ratio of t2/t1 is at least 1/10, wherein t2 is at least 25 μm (microns) and not greater than 200 μm (microns). a load bearing substrate, having a first major surface, a second major surface, and an edge, the load bearing substrate having a thickness t1, a metal containing layer (104; 1042) which is a corrosion protective layer and which is overlying and in direct contact with the first major surface, the metal containing layer (104; 1042) having a thickness t2, wherein the metal containing layer (104; 1042) contains a metal selected from magnesium, aluminum, titanium, scandium, zinc, or any combination thereof, a sliding layer overlying the first or the second major surface, characterized in that a ratio of t2/t1 is at least 1/10, wherein t2 is at least 25 μm (microns) and not greater than 200 μm (microns).
An acoustic speaker consisting of the enclosure and speakers: woofer and wideband speaker, wherein the enclosure consists of a set of at least three upper chambers separated from each other by partitions, and a set of lower chambers separated from each other by partitions, the number of lower chambers corresponding to the number of upper chambers, whereby every second partition in the set of upper chambers, starting from an upper first partition is closed, and in every second partition, starting from an upper second partition at least one opening is made, whereas in a lower chambers set, it is the opposite, i.e. in every second partition at least one opening is made, starting from a lower first partition and every second partition, starting from lower second partition is closed, moreover the main axis of the wideband speaker with the outlet for acoustic wave emission is directed parallel to the floor, and the wideband speaker is mounted in an upper first chamber, whereas the main axis of the woofer with the outlet of acoustic wave emission is directed vertically down, and the woofer is mounted in a lower first chamber and a lower second chamber, moreover each of an upper chambers is mounted onto a respective lower chamber located below it via a waveguide made of hollow pipe, whereby a first waveguide is closed at the bottom and open at the top creating with an upper first chamber a separate space, and the remaining waveguides are open from both sides, creating with the following upper and lower chambers a low-pass acoustic filter whose order depends on the number of chambers and waveguides, moreover the set of upper chambers and set of lower chambers are additionally connected by means of front bars and rear bars pressing and tightening the whole enclosure, whereby the front bars are at the same time a metallic conductive connection between the wideband speaker and feeder clamps coming out in the set of lower chambers, whereas the rear bars provide support and stiffening for the whole structure.
A thermoplastic resin composition, comprising: 100 parts by weight of a thermoplastic resin (a) that is a liquid crystalline polyester; and 0.001 to 10 parts by weight of a metal complex (b) having: a monodentate or a bidentate ligand; and at least one metal and/or its salt selected from the group consisting of copper, zinc, nickel, manganese, cobalt, chromium and tin. 100 parts by weight of a thermoplastic resin (a) that is a liquid crystalline polyester; and 0.001 to 10 parts by weight of a metal complex (b) having: a monodentate or a bidentate ligand; and at least one metal and/or its salt selected from the group consisting of copper, zinc, nickel, manganese, cobalt, chromium and tin. a monodentate or a bidentate ligand; and at least one metal and/or its salt selected from the group consisting of copper, zinc, nickel, manganese, cobalt, chromium and tin.
An integrated MSD connector test device, comprising: a housing; an MSD connector housed in the housing and having a first polarity contact and a second polarity contact, wherein the second polarity contact comprises two contact portions (342,344) separated from each other; and a first polarity port and a second polarity port accessible from outside of the housing, the first polarity port being electrically connected to the first polarity contact, and the second polarity port being electrically connected to one of the contact portions, (342,344) wherein the first polarity is a positive or negative, and correspondingly, the second polarity is a negative or positive, characterised in that the MSD connector test device further comprises a cable extending at least partially outside of the housing, two ends of the cable being electrically connected to the two contact portions respectively. a housing; an MSD connector housed in the housing and having a first polarity contact and a second polarity contact, wherein the second polarity contact comprises two contact portions (342,344) separated from each other; and a first polarity port and a second polarity port accessible from outside of the housing, the first polarity port being electrically connected to the first polarity contact, and the second polarity port being electrically connected to one of the contact portions, (342,344) wherein the first polarity is a positive or negative, and correspondingly, the second polarity is a negative or positive, characterised in that the MSD connector test device further comprises a cable extending at least partially outside of the housing, two ends of the cable being electrically connected to the two contact portions respectively.
A tire comprising a tread portion, wherein the tread portion includes a first land portion demarcated by circumferential grooves continuously extending in a tire circumferential direction, and a plurality of first lateral grooves inclined in a first direction relative to a tire axial direction and traversing the first land portion, the first land portion includes a plurality of first blocks demarcated by the first lateral grooves, each first block has at least one sipe inclined in a second direction opposite to the first direction, relative to the tire axial direction, characterized in that the sipe includes a portion deeper than a maximum depth of the first lateral groove, and a portion shallower than the maximum depth of the first lateral groove. the tread portion includes a first land portion demarcated by circumferential grooves continuously extending in a tire circumferential direction, and a plurality of first lateral grooves inclined in a first direction relative to a tire axial direction and traversing the first land portion, the first land portion includes a plurality of first blocks demarcated by the first lateral grooves, each first block has at least one sipe inclined in a second direction opposite to the first direction, relative to the tire axial direction, characterized in that the sipe includes a portion deeper than a maximum depth of the first lateral groove, and a portion shallower than the maximum depth of the first lateral groove.
A computer-implemented method, comprising: collecting state information from a plurality of network devices in a network, wherein the state information is collected by taking a snapshot of the plurality of network devices, wherein the state information includes forwarding states; parsing (604, 606), by a plurality of network device-specific parsers, the state information to translate the state information into a network model, wherein the network model is based on a series of forwarding tables (304, 306, 308) which describe how data is processed by the network; and computing (608, 610) one or more flow paths based on symbolic packets pushed through the network model, wherein the symbolic packets include one or more wild card bits and identify a packet or class of packets as the packet or the class of packets travel through the network, wherein a modification to the packet or the class of packets along the one or more flow paths is computed by pushing the symbolic packets through the network model. collecting state information from a plurality of network devices in a network, wherein the state information is collected by taking a snapshot of the plurality of network devices, wherein the state information includes forwarding states; parsing (604, 606), by a plurality of network device-specific parsers, the state information to translate the state information into a network model, wherein the network model is based on a series of forwarding tables (304, 306, 308) which describe how data is processed by the network; and computing (608, 610) one or more flow paths based on symbolic packets pushed through the network model, wherein the symbolic packets include one or more wild card bits and identify a packet or class of packets as the packet or the class of packets travel through the network, wherein a modification to the packet or the class of packets along the one or more flow paths is computed by pushing the symbolic packets through the network model.
A method of forming an electrode suitable for an analyte sensor apparatus, the method comprising: (a) disposing a monomer mixture on the electrode, the monomer mixture comprising: a plurality of hydroxyethyl methacrylate (HEMA) monomers; one or more di-acrylate crosslinkers; one or more ultraviolet photoinitiators; and an oxidoreductase, wherein the oxidoreductase is a glucose oxidase-acrylate bioconjugate; (b) polymerizing the monomer mixture with UV light in situ so as to form a crosslinked polymer matrix on the electrode, wherein polymerizing the monomer mixture with UV light comprises masking an area of the deposited monomer mixture so as to prevent the monomer mixture from forming a crosslinked polymer matrix over a sensor substrate area; (c) disposing a glucose limiting membrane mixture at least partially over the crosslinked polymer matrix, the membrane mixture comprising: a plurality of HEMA monomers; one or more di-acrylate crosslinkers; one or more UV photoinitiators; ethylene glycol; and water; and (d) polymerizing the glucose limiting membrane mixture in situ with UV light, so that the glucose limiting membrane formed functions to restrict the diffusion of glucose through the glucose limiting membrane and facilitate the diffusion of O 2 through the glucose limiting membrane. (a) disposing a monomer mixture on the electrode, the monomer mixture comprising: a plurality of hydroxyethyl methacrylate (HEMA) monomers; one or more di-acrylate crosslinkers; one or more ultraviolet photoinitiators; and an oxidoreductase, wherein the oxidoreductase is a glucose oxidase-acrylate bioconjugate; a plurality of hydroxyethyl methacrylate (HEMA) monomers; one or more di-acrylate crosslinkers; one or more ultraviolet photoinitiators; and an oxidoreductase, wherein the oxidoreductase is a glucose oxidase-acrylate bioconjugate; (b) polymerizing the monomer mixture with UV light in situ so as to form a crosslinked polymer matrix on the electrode, wherein polymerizing the monomer mixture with UV light comprises masking an area of the deposited monomer mixture so as to prevent the monomer mixture from forming a crosslinked polymer matrix over a sensor substrate area; (c) disposing a glucose limiting membrane mixture at least partially over the crosslinked polymer matrix, the membrane mixture comprising: a plurality of HEMA monomers; one or more di-acrylate crosslinkers; one or more UV photoinitiators; ethylene glycol; and water; and a plurality of HEMA monomers; one or more di-acrylate crosslinkers; one or more UV photoinitiators; ethylene glycol; and water; and (d) polymerizing the glucose limiting membrane mixture in situ with UV light, so that the glucose limiting membrane formed functions to restrict the diffusion of glucose through the glucose limiting membrane and facilitate the diffusion of O 2 through the glucose limiting membrane.
A pharmaceutical composition comprising a serum amyloid P variant comprising five SAP protomers, wherein each of the SAP protomers have an amino acid sequence at least 95% identical to SEQ ID NO: 1, and wherein all five SAP protomers comprise an amino acid at position 167 of SEQ ID NO: 1 that is asparagine, glutamine, alanine, or histidine, and a pharmaceutically acceptable ophthalmic vehicle.
An EUV excitation light source, comprising: - a laser source that is configured to emit a laser beam, the laser beam comprising two partial beams (1', 1") having different wavelengths (λ 1, λ 2), - a separating optical element for separating the two partial beams (1', 1") of the laser beam into two separated beams (2', 2"), and - a superposition unit for superimposing the two separated beams (2', 2") at a predefined superposition location with a predefined superposition angle (α), characterized in that the separating optical element is a first reflective diffraction grating. - a laser source that is configured to emit a laser beam, the laser beam comprising two partial beams (1', 1") having different wavelengths (λ 1, λ 2), - a separating optical element for separating the two partial beams (1', 1") of the laser beam into two separated beams (2', 2"), and - a superposition unit for superimposing the two separated beams (2', 2") at a predefined superposition location with a predefined superposition angle (α),
A mobile station comprising: means for controlling periodically a control cycle for a discontinuous reception, the control cycle being constant and comprising a reception period and a reception halt period, whereby the control cycle is the total of both periods; means for receiving, from a base station, a retransmission data according to a Hybrid Automatic Repeat reQuest, HARQ, process or a new transmission data; means for determining, based on the HARQ process, whether the retransmission data or the new transmission data is successfully received or not; and means for transmitting, to the base station, a reception result of the retransmission data or the new transmission data, as a reception result notification signal according to the HARQ process; the mobile station characterized by comprising: means for extending the reception period in the control cycle if the retransmission data or the new transmission data have been determined to be not successfully received, wherein the ratio of the reception period and the reception halt period in the control cycle is dynamically changed during operation, and the means for receiving, being further adapted to receive, in the extended reception period in the control cycle, a further retransmission data. means for controlling periodically a control cycle for a discontinuous reception, the control cycle being constant and comprising a reception period and a reception halt period, whereby the control cycle is the total of both periods; means for receiving, from a base station, a retransmission data according to a Hybrid Automatic Repeat reQuest, HARQ, process or a new transmission data; means for determining, based on the HARQ process, whether the retransmission data or the new transmission data is successfully received or not; and means for transmitting, to the base station, a reception result of the retransmission data or the new transmission data, as a reception result notification signal according to the HARQ process; the mobile station characterized by comprising: means for extending the reception period in the control cycle if the retransmission data or the new transmission data have been determined to be not successfully received, wherein the ratio of the reception period and the reception halt period in the control cycle is dynamically changed during operation, and the means for receiving, being further adapted to receive, in the extended reception period in the control cycle, a further retransmission data. means for extending the reception period in the control cycle if the retransmission data or the new transmission data have been determined to be not successfully received, wherein the ratio of the reception period and the reception halt period in the control cycle is dynamically changed during operation, and the means for receiving, being further adapted to receive, in the extended reception period in the control cycle, a further retransmission data.
A computer-implemented medical data processing method for determining a position of a brain sulcus in the brain of a patient, the method comprising executing, on at least one processor of at least one computer, steps of: a) acquiring, at the at least one processor, patient image data describing a digital medical image of at least part of the brain; b) acquiring, at the at least one processor, atlas data describing an image-based model of the at least part of the brain; c) determining, by the at least one processor and based on the patient image data and the atlas data, mapping data describing a transformation between the patient image data and the atlas data; d) determining, by the at least one processor and based on the patient image data and the atlas data and the mapping data, sulcus position data describing the position of the brain sulcus in the digital medical image, characterized in that the digital medical image is represented by a data set representing a curved surface which is defined in three dimensions r ( θ, φ), and wherein the sulcus position data is determined in a projection of the digital medical image onto a planar surface which is defined in two dimensions (x, y), and in that the sulcus position data is determined based on masking the projected digital medical image and filtering the masked projected digital medical image by applying a two-dimensional filament detection filter. a) acquiring, at the at least one processor, patient image data describing a digital medical image of at least part of the brain; b) acquiring, at the at least one processor, atlas data describing an image-based model of the at least part of the brain; c) determining, by the at least one processor and based on the patient image data and the atlas data, mapping data describing a transformation between the patient image data and the atlas data; d) determining, by the at least one processor and based on the patient image data and the atlas data and the mapping data, sulcus position data describing the position of the brain sulcus in the digital medical image,
A variable helmet comprising: a protective pad in which a plurality of unit pads are planarly coupled like a mosaic so that the protective pad is in a hemispherical shape to cover and protect a head and is able to be unfolded flat like a plate, the protective pad having unevenness portions provided in a sawtooth shape at both ends thereof; both-end fixing means allowing the unit pads to have a hemispherical shape by tightening the both ends of the protective pad; and a chin strap allowing the protective pad to be fixed in a state in which the protective pad is covered on the head, the chin strap being installed in the protective pad so as to support a chin of a wearer; and characterized in that the both-end fixing means include, insertion portions that are provided in both edges of the protective pad; and adjustment strap members (200, 300) that are fitted into the insertion portions to thereby change a shape of the protective pad. a protective pad in which a plurality of unit pads are planarly coupled like a mosaic so that the protective pad is in a hemispherical shape to cover and protect a head and is able to be unfolded flat like a plate, the protective pad having unevenness portions provided in a sawtooth shape at both ends thereof; both-end fixing means allowing the unit pads to have a hemispherical shape by tightening the both ends of the protective pad; and a chin strap allowing the protective pad to be fixed in a state in which the protective pad is covered on the head, the chin strap being installed in the protective pad so as to support a chin of a wearer; and characterized in that the both-end fixing means include, insertion portions that are provided in both edges of the protective pad; and adjustment strap members (200, 300) that are fitted into the insertion portions to thereby change a shape of the protective pad.