A compound comprising the structure of Formula: or a pharmaceutically acceptable salt thereof, wherein: L is selected from the group consisting of a bond, -C NH-, -SO 2 -, methylene, ethylene, and wherein the R 9 and R 10 groups together with the carbon atom to which they are bonded may optionally join together to form a cyclopropyl ring; R 1 is selected from (C 1 -C 6)alkyl or (C 3 -C 7)cycloalkyl; R 2 is carboxyl; R 3 is tert-butoxy; R 4 is selected from the group consisting of phenyl, dihydrobenzopyranyl, dihydrooxazine, naphthalenyl, pyridinyl, pyrrolyl, pyrrolidinyl, pyrrolinyl, piperidinyl, benzodioxolyl, benzodioxinyl, dihydrobenzodioxepinyl, quinolinyl, dihydrobenzofuranyl, tetrahydroisoquinolinyl, dihydrobenzoxazinyl, dihydroindenyl, benzothiazolyl, cyclohexenyl, furanyl, pyrazolyl, and tetrahydropyridoquinolinyl, and is optionally substituted by one to three groups selected from methyl, ethyl, oxo, methoxy, ethoxy, propoxy, methoxymethyl, fluoro, chloro, bromo, trifluoromethoxy, trifluoromethyl, methylsulfonyl, dimethylamide, cyclohexyloxy, acetyl, and fluoromethyl; R 5, R 6, and R 7 are are independently selected from the group consisting of -H, methyl, ethyl, propyl, butyl, hydroxyl, fluoro, chloro, bromo, methoxy, ethoxy, propoxy, methoxyethoxy, cyclopropyl, cyclohexyl, fluorophenylmethoxy, difluorophenylmethoxy, pyridinylmethoxy, trifluorophenylmethoxy, fluoropyridinylmethoxy, methylpyridinylmethoxy, phenyl, dimethyloxazolylmethoxy, thiophenylmethoxy, fluoroethoxy, chlorothiophenylmethoxy, methylthiophenylmethoxy, hydroxyethoxy, dimethylaminoethoxy, difluoromethoxy, pyrrolidinylethoxy, morpholinylethoxy, carboxylmethoxy, dimethylsulfamoyloxy, trifluoromethyl, methylsulfonylphenylmethoxy, chlorophenylmethoxy, pyrimidinylmethoxy, trifluoromethoxyphenylmethoxy, chlorobromophenylamino, piperidinyl, piperidinylmethyl, dioxothiomorpholinyl, morpholinyl, morpholinylcarbonyl, ethylamide, fluorophenyl, methoxyphenylmethyl, methylpyridinyl, phenylmethyl, phenylethyl, nitrile, aminocarbonyl, aminomethyl, morpholinylmethyl, bis(pyridinylmethyl)aminomethyl, pentylpyrazolyl, pyridinylmethylaminomethyl, acetamidomethyl, ethylureidomethyl, pyridinyl, carboxyformamidomethyl, methylsulfonamidomethyl, dimethylaminophenyl, dimethylaminosulfonylaminomethyl, methylpyrrolyl, methylpyrazolyl, methylfuranyl, furanyl, dimethylpyrazolyl, pyrazolyl, methoxypyridinyl, and dimethylisoxazolyl, and wherein R 7 is substituted by zero to four substituents selected from the group consisting of halo, (C 1 -C 6)alkyl, (C 1 -C 6)alkoxy, trifluoroalkyl, trifluoroalkoxy, triazolyl, and butoxycarbonyl; R 9 is independently selected from -H and (C 1 -C 6)alkyl; and R 10 is (C 1 -C 6)alkyl. L is selected from the group consisting of a bond, -C NH-, -SO 2 -, methylene, ethylene, and wherein the R 9 and R 10 groups together with the carbon atom to which they are bonded may optionally join together to form a cyclopropyl ring; R 1 is selected from (C 1 -C 6)alkyl or (C 3 -C 7)cycloalkyl; R 2 is carboxyl; R 3 is tert-butoxy; R 4 is selected from the group consisting of phenyl, dihydrobenzopyranyl, dihydrooxazine, naphthalenyl, pyridinyl, pyrrolyl, pyrrolidinyl, pyrrolinyl, piperidinyl, benzodioxolyl, benzodioxinyl, dihydrobenzodioxepinyl, quinolinyl, dihydrobenzofuranyl, tetrahydroisoquinolinyl, dihydrobenzoxazinyl, dihydroindenyl, benzothiazolyl, cyclohexenyl, furanyl, pyrazolyl, and tetrahydropyridoquinolinyl, and is optionally substituted by one to three groups selected from methyl, ethyl, oxo, methoxy, ethoxy, propoxy, methoxymethyl, fluoro, chloro, bromo, trifluoromethoxy, trifluoromethyl, methylsulfonyl, dimethylamide, cyclohexyloxy, acetyl, and fluoromethyl; R 5, R 6, and R 7 are are independently selected from the group consisting of -H, methyl, ethyl, propyl, butyl, hydroxyl, fluoro, chloro, bromo, methoxy, ethoxy, propoxy, methoxyethoxy, cyclopropyl, cyclohexyl, fluorophenylmethoxy, difluorophenylmethoxy, pyridinylmethoxy, trifluorophenylmethoxy, fluoropyridinylmethoxy, methylpyridinylmethoxy, phenyl, dimethyloxazolylmethoxy, thiophenylmethoxy, fluoroethoxy, chlorothiophenylmethoxy, methylthiophenylmethoxy, hydroxyethoxy, dimethylaminoethoxy, difluoromethoxy, pyrrolidinylethoxy, morpholinylethoxy, carboxylmethoxy, dimethylsulfamoyloxy, trifluoromethyl, methylsulfonylphenylmethoxy, chlorophenylmethoxy, pyrimidinylmethoxy, trifluoromethoxyphenylmethoxy, chlorobromophenylamino, piperidinyl, piperidinylmethyl, dioxothiomorpholinyl, morpholinyl, morpholinylcarbonyl, ethylamide, fluorophenyl, methoxyphenylmethyl, methylpyridinyl, phenylmethyl, phenylethyl, nitrile, aminocarbonyl, aminomethyl, morpholinylmethyl, bis(pyridinylmethyl)aminomethyl, pentylpyrazolyl, pyridinylmethylaminomethyl, acetamidomethyl, ethylureidomethyl, pyridinyl, carboxyformamidomethyl, methylsulfonamidomethyl, dimethylaminophenyl, dimethylaminosulfonylaminomethyl, methylpyrrolyl, methylpyrazolyl, methylfuranyl, furanyl, dimethylpyrazolyl, pyrazolyl, methoxypyridinyl, and dimethylisoxazolyl, and wherein R 7 is substituted by zero to four substituents selected from the group consisting of halo, (C 1 -C 6)alkyl, (C 1 -C 6)alkoxy, trifluoroalkyl, trifluoroalkoxy, triazolyl, and butoxycarbonyl; R 9 is independently selected from -H and (C 1 -C 6)alkyl; and R 10 is (C 1 -C 6)alkyl.