mhurhangee/ep-ind-claims huggingface dataset:
A crystalline dry powder composition comprising a plurality of microcrystalline particles of 3,6-bis(N-fumaryl-4-aminobutyl)-2,5-diketopiperazine, uniform in size, having a hollow spherical structure and comprising a shell comprising crystallites of the 3,6-bis(N-fumaryl-4-aminobutyl)-2,5-diketopiperazine that do not self-assemble in a suspension, wherein the particles are formed without the presence of a surfactant by a method comprising: forming the 3,6-bis(N-4-aminobutyl)-2,5-diketopiperazine particles in a suspension having a bimodal distribution in the particle sizes which range from about 0.05 μm to about 10 μm; atomizing the suspension using a spray dryer under an air or gas stream, and reforming particles by spray-drying to form the dry powder, wherein up to 92% of the microcrystalline particles have a volumetric median geometric diameter of ≤ 5.8 μm.
An apparatus for examining breast tissue, comprising: a flexible dome-shaped substrate (204, 301) defining an internal surface arranged to accommodate breast tissue; a set of substantially circular electrodes, arranged as concentric rings, located on said substrate; a set of substantially radial electrodes (501, 502), each overlapping said concentric rings, located on said substrate; an energising circuit configured for energising a transmitter electrode selected from said plurality of electrodes to propagate an electric field through a detection region of said breast tissue during a coupling operation; and a monitoring circuit configured for receiving an output signal from a receiver electrode selected from the remaining electrodes of said plurality of electrodes; and identifying positions within said detection region by coordinates established by said substantially circular electrodes and said substantially radial electrodes. a flexible dome-shaped substrate (204, 301) defining an internal surface arranged to accommodate breast tissue; a set of substantially circular electrodes, arranged as concentric rings, located on said substrate; a set of substantially radial electrodes (501, 502), each overlapping said concentric rings, located on said substrate; an energising circuit configured for energising a transmitter electrode selected from said plurality of electrodes to propagate an electric field through a detection region of said breast tissue during a coupling operation; and a monitoring circuit configured for receiving an output signal from a receiver electrode selected from the remaining electrodes of said plurality of electrodes; and identifying positions within said detection region by coordinates established by said substantially circular electrodes and said substantially radial electrodes.
A roller lock, comprising: a lock to engage with a roller of a feed system, the lock including a coupling to operably engage with a complementary coupling of the roller; and characterised by: a leadscrew to engage with the lock, the leadscrew including an advancer to engage with the lock such that the advancer translates the lock along a longitudinal axis of the roller so that the lock may engage and disengage with the roller to intermittently prevent the roller from rotating in a forward direction.
A powder material impregnation method comprising: a first step of dispersing a powder of a predetermined material in a liquid to prepare a slurry; and a second step of burying a molded fabric body made of fiber bundles in the slurry and vibrating the slurry by use of a plurality of vibrators provided at predetermined intervals in a frame body the shape of which follows and is slightly larger than a cross-sectional shape of the molded fabric body; wherein, in the second step, the vibrator frame is moved along a side surface of the molded fabric body in a direction normal to the cross-sectional shape, so as to move over the whole side surface of the molded fabric body, and wherein the fiber material is one or more of non-oxide inorganic materials, oxide inorganic materials, and carbon. a first step of dispersing a powder of a predetermined material in a liquid to prepare a slurry; and a second step of burying a molded fabric body made of fiber bundles in the slurry and vibrating the slurry by use of a plurality of vibrators provided at predetermined intervals in a frame body the shape of which follows and is slightly larger than a cross-sectional shape of the molded fabric body; wherein, in the second step, the vibrator frame is moved along a side surface of the molded fabric body in a direction normal to the cross-sectional shape, so as to move over the whole side surface of the molded fabric body, and wherein the fiber material is one or more of non-oxide inorganic materials, oxide inorganic materials, and carbon.
A method for wireless communication at a user equipment, UE, comprising: receiving a plurality of reference signals, wherein each reference signal of the plurality of reference signals corresponds to at least one transmission opportunity for a random access channel, RACH, preamble message transmission; determining a number of RACH preamble messages to transmit in response to the received plurality of reference signals, wherein the determining is based at least in part on a capability of the UE to simultaneously monitor for random access response, RAR, messages corresponding to the number of RACH preamble messages; and transmitting the determined number of RACH preamble messages based at least in part on the determining, wherein each RACH preamble message of the number of RACH preamble messages corresponds to a reference signal of the received plurality of reference signals. receiving a plurality of reference signals, wherein each reference signal of the plurality of reference signals corresponds to at least one transmission opportunity for a random access channel, RACH, preamble message transmission; determining a number of RACH preamble messages to transmit in response to the received plurality of reference signals, wherein the determining is based at least in part on a capability of the UE to simultaneously monitor for random access response, RAR, messages corresponding to the number of RACH preamble messages; and transmitting the determined number of RACH preamble messages based at least in part on the determining, wherein each RACH preamble message of the number of RACH preamble messages corresponds to a reference signal of the received plurality of reference signals.
A method for producing an electronic part mounting substrate comprising an electronic part mounted on one side of a metal plate of aluminum or an aluminum alloy, the method comprising the steps of: applying a silver paste directly on the one side of the metal plate; arranging the electronic part on the silver paste applied on the one side of the metal plate, the electronic part having a surface to be bonded to the one side of the metal plate, the surface being covered with a metal capable of being bonded with the silver paste, said metal being in contact with the silver paste; and sintering silver in the silver paste to form a silver bonding layer to bond the electronic part to the one side of the metal plate with the silver bonding layer, characterized in that the method further comprises a step of surface-machining the one side of the metal plate so as to cause the surface roughness thereof to be 0.2 to 2.0 micrometers before the silver paste is applied on the surface-machined surface of the metal plate, the surface roughness being an arithmetic surface roughness Ra calculated on the basis of JIS B0601, and in that the silver paste is a bonding agent wherein fine silver particles having an average primary particle diameter of 1 to 200 nm coated with an organic compound having 8 or less of carbon atoms are dispersed in a dispersing medium. applying a silver paste directly on the one side of the metal plate; arranging the electronic part on the silver paste applied on the one side of the metal plate, the electronic part having a surface to be bonded to the one side of the metal plate, the surface being covered with a metal capable of being bonded with the silver paste, said metal being in contact with the silver paste; and sintering silver in the silver paste to form a silver bonding layer to bond the electronic part to the one side of the metal plate with the silver bonding layer, characterized in that the method further comprises a step of surface-machining the one side of the metal plate so as to cause the surface roughness thereof to be 0.2 to 2.0 micrometers before the silver paste is applied on the surface-machined surface of the metal plate, the surface roughness being an arithmetic surface roughness Ra calculated on the basis of JIS B0601, and in that the silver paste is a bonding agent wherein fine silver particles having an average primary particle diameter of 1 to 200 nm coated with an organic compound having 8 or less of carbon atoms are dispersed in a dispersing medium.
A method for inducing differentiation of pluripotent stem cells into intestinal epithelial cells, the method comprising the following steps and: the step of differentiating pluripotent stem cells into intestinal stem cell-like cells; and the step of differentiating the intestinal stem cell-like cells obtained in the step into intestinal epithelial cell-like cells by using an MEK1 inhibitor, a DNA methylation inhibitor, a TGFβ receptor inhibitor, EGF, and a cAMP activator in combination, wherein the cAMP activator is Forskolin or NKH477. the step of differentiating pluripotent stem cells into intestinal stem cell-like cells; and the step of differentiating the intestinal stem cell-like cells obtained in the step into intestinal epithelial cell-like cells by using an MEK1 inhibitor, a DNA methylation inhibitor, a TGFβ receptor inhibitor, EGF, and a cAMP activator in combination, wherein the cAMP activator is Forskolin or NKH477.
Measuring device comprising - a radio interface via which data of a contactless temperature measurement can be transmitted to a control unit; - a microcontroller which is connected to a measuring sensor; - a housing, wherein a lower side of the housing has a connector which provides a fixing point for an objective in a movable and height-adjustable objective revolving nosepiece of an inverted microscope, and which is equipped with the measuring sensor within the housing on an upper side opposite the lower side, by means of which the contactless temperature measurement can be carried out on a bottom of a culture vessel, provided that the housing is brought into a beam path of the inverted microscope at the selected objective position in the revolving nosepiece, so that the measuring device is aligned vertically and is located below the bottom of the culture vessel, wherein a tilt sensor is disposed within the housing and is capable of emitting a signal indicating the moving of the housing into the beam path of the inverted microscope at the selected objective location in the revolving nosepiece when the measuring device is vertically aligned and is located below the bottom of the culture vessel, wherein the emitted signal controls the power supply to the measuring sensor and/or the microcontroller and/or the radio interface in such a way that, when the housing is located outside the beam path and the measuring device has left the vertical orientation, the power consumption can be minimised by switching off components which are no longer required. - a radio interface via which data of a contactless temperature measurement can be transmitted to a control unit; - a microcontroller which is connected to a measuring sensor; - a housing, wherein a lower side of the housing has a connector which provides a fixing point for an objective in a movable and height-adjustable objective revolving nosepiece of an inverted microscope, and which is equipped with the measuring sensor within the housing on an upper side opposite the lower side, by means of which the contactless temperature measurement can be carried out on a bottom of a culture vessel, provided that the housing is brought into a beam path of the inverted microscope at the selected objective position in the revolving nosepiece, so that the measuring device is aligned vertically and is located below the bottom of the culture vessel, wherein a tilt sensor is disposed within the housing and is capable of emitting a signal indicating the moving of the housing into the beam path of the inverted microscope at the selected objective location in the revolving nosepiece when the measuring device is vertically aligned and is located below the bottom of the culture vessel, wherein the emitted signal controls the power supply to the measuring sensor and/or the microcontroller and/or the radio interface in such a way that, when the housing is located outside the beam path and the measuring device has left the vertical orientation, the power consumption can be minimised by switching off components which are no longer required.
An optoelectronic sensor, in particular laser scanner, for detecting objects in a monitoring area, the sensor comprising a light transmitter for transmitting transmitted light, a movable deflection unit for periodically deflecting the transmitted light, a light receiver for generating a received signal from remitted transmitted light that is remitted by objects in the monitoring area, a shielding device which is moved at least partially with the deflection unit and is arranged around the beam path of the transmitted light in order to suppress crosstalk of the transmitted light to the light receiver, a control and evaluation unit for detecting information about objects in the monitored area on the basis of the received signal, a circumferential front window for the light transmission of the transmitted light, and a reference target for a function test and/or calibration of the sensor, wherein the reference target is configured by its construction and/or arrangement for a closely approached passing movement of the shielding device, characterized in that the reference target is arranged at least partially recessed in an inner pocket of the front window.
Stuffer assembly for an agricultural baler comprising: a stuffer chute for collecting and precompressing a charge of crop material; and a stuffer configured to transfer the charge of crop material collected within the stuffer chute into a baling chamber of the agricultural baler; wherein the stuffer comprises a stuffer arm having a tine bar mounted to one end of the stuffer arm, wherein the tine bar comprises a plurality of tines; characterized by wherein each tine of the plurality of tines is slidably connected to the tine bar such that each tine of the plurality of tines is linearly movable with respect to the tine bar between an extended position and a retracted position in a direction parallel to a radial direction of the tine bar. a stuffer chute for collecting and precompressing a charge of crop material; and a stuffer configured to transfer the charge of crop material collected within the stuffer chute into a baling chamber of the agricultural baler; wherein the stuffer comprises a stuffer arm having a tine bar mounted to one end of the stuffer arm, wherein the tine bar comprises a plurality of tines; characterized by wherein each tine of the plurality of tines is slidably connected to the tine bar such that each tine of the plurality of tines is linearly movable with respect to the tine bar between an extended position and a retracted position in a direction parallel to a radial direction of the tine bar.
A console for a vehicle interior configured to position at least one mobile device connectable by a cable comprising: - a base providing a compartment; - a cover for the compartment comprising a cradle (58a-c) and movable to an open position; - a bin comprising an opening configured to provide storage for at least a portion of the cable; and - a cover for the bin; wherein the cradle (58a-c) is configured to support the at least one mobile device; wherein the cover for the bin is configured to facilitate access for the cable in the bin; wherein the console comprises a spring configured to bias the cover toward the open position. - a base providing a compartment; - a cover for the compartment comprising a cradle (58a-c) and movable to an open position; - a bin comprising an opening configured to provide storage for at least a portion of the cable; and - a cover for the bin;
A sliding bearing ( 1, 1', 1", 1 IV), usable for example as a seismic isolator, arranged for supporting civil or structural engineering works, such as for example bridges or buildings, silos, tanks or large-dimension cranes, nuclear reactors or components thereof, wherein the bearing ( 1, 1', 1", 1 IV) comprises: - a base and an upper support; - a sliding element (7, 7') interposed between the base and the upper support, and against which the base and the upper support rest; and wherein the sliding element (7, 7 ') comprises at least one layer ( 11, 11', 11", 11 III) made of a sliding material comprising in its turn a content by weight equal to or greater than 50 %wt of one or more fluorinated polymers; characterised in that the sliding material further comprises a content by weight comprised between 1-20 % wt of boron nitride in hexagonal form. - a base and an upper support; - a sliding element (7, 7') interposed between the base and the upper support, and against which the base and the upper support rest; and wherein the sliding element (7, 7 ') comprises at least one layer ( 11, 11', 11", 11 III) made of a sliding material comprising in its turn a content by weight equal to or greater than 50 %wt of one or more fluorinated polymers; characterised in that the sliding material further comprises a content by weight comprised between 1-20 % wt of boron nitride in hexagonal form.
An access point entity, comprising a storage for storing user-specific content preferences, the user-specific content preferences indicating contents associated with each user of a certain group of users; and a processor for aggregating the user-specific content preferences to obtain a group-specific set of content preferences, the group-specific set of content preferences indicating group-specific contents associated with the certain group of users; wherein the access point entity is configured to transmit the group-specific set of content preferences towards a communication network; and wherein the access point entity is further configured to receive a content matching at least one content specified in the group-specific set of content preferences from the communication network; characterized in that, the access point entity is further configured to request the users of the certain group of users to transmit the user-specific content preferences towards the access point entity; and the access point entity is further configured to receive the user-specific content preferences from the users of the certain group of users.
Process for the production of panels made of wooden material comprising at least the following phases: - supply of a plurality of types of wooden material (S1,S2,P) in the form of flakes and/or dust; - forming of at least one support layer in at least one of said types of wooden material (S1,S2) on a work surface; - forming of at least one final layer on top of said support layer, in another of said types of wooden material (S1,S2,P) other than that of the support layer itself, so as to form a mattress; - compacting of said mattress to form a compacted panel made of wooden material; wherein, after said formation of said at least one support layer and before said formation of said at least one final layer, at least one steam heating phase and one pressing phase of said at least one support layer to obtain a pre-compacted mattress, the process comprises, before said forming of said at least one support layer, a forming phase of a plurality of said base layers, each of which is made of one of said types of wooden material (S1, S2, P) other than that of at least one of the adjacent base layers and by the fact that said steam heating and said pressing are carried out substantially at the same time, where said steam heating is carried out by means of dispensing of steam on said at least one support layer. - supply of a plurality of types of wooden material (S1,S2,P) in the form of flakes and/or dust; - forming of at least one support layer in at least one of said types of wooden material (S1,S2) on a work surface; - forming of at least one final layer on top of said support layer, in another of said types of wooden material (S1,S2,P) other than that of the support layer itself, so as to form a mattress; - compacting of said mattress to form a compacted panel made of wooden material; wherein, after said formation of said at least one support layer and before said formation of said at least one final layer, at least one steam heating phase and one pressing phase of said at least one support layer to obtain a pre-compacted mattress, the process comprises, before said forming of said at least one support layer, a forming phase of a plurality of said base layers, each of which is made of one of said types of wooden material (S1, S2, P) other than that of at least one of the adjacent base layers and by the fact that said steam heating and said pressing are carried out substantially at the same time, where said steam heating is carried out by means of dispensing of steam on said at least one support layer.
A carbon black Ink-jet ink, comprising from 0.5 wt % to 10 wt % of a self-dispersed carbon black pigment, having a base carbon DBP value of less than 60 and a liquid vehicle containing water and an organic solvent.
An in-vitro method of identifying a responder patient population for treatment with an exogenous agent comprising: (a) establishing a cellular model of disease space based on one or more signaling pathway; (b) identifying the effect of the exogenous agent in the one or more signaling pathway; (c) determining a biomarker responder package including a plurality of biomarkers, wherein the plurality of biomarkers are specific for one or more of the signaling pathway, and the biomarkers are antibodies directed against post- translationally modified proteins; (d) assaying the state of the one or more signaling pathway with the biomarker responder package before and after drug dosing; and (e) identifying the responder patient population that will be responsive for the exogenous agent based on the assay. (a) establishing a cellular model of disease space based on one or more signaling pathway; (b) identifying the effect of the exogenous agent in the one or more signaling pathway; (c) determining a biomarker responder package including a plurality of biomarkers, wherein the plurality of biomarkers are specific for one or more of the signaling pathway, and the biomarkers are antibodies directed against post- translationally modified proteins; (d) assaying the state of the one or more signaling pathway with the biomarker responder package before and after drug dosing; and (e) identifying the responder patient population that will be responsive for the exogenous agent based on the assay.