A method for radio frequency fingerprint database creation, applied at a centralized processing device, the radio frequency fingerprint database for being delivered to a base station for radio resource management, the method comprising: dividing a cell into a plurality of grids according to a plurality of grid indexes and historical data reported by each of a plurality of terminals in the cell, wherein one grid index is used to uniquely identify one grid whereby the grid logically divides the cell based on a wireless communication characteristic of each terminal within the cell; performing (S 104) neighbor cell information statistics on each of a plurality of neighbor cells of the cell in each of the plurality of grids; and generating an effective radio frequency fingerprint database corresponding to the cell according to a result of the dividing and a result of the neighbor cell information statistics; wherein each of the plurality of grid indexes comprises a serving cell identification and serving cell quality; and dividing the cell into the plurality of grids according to the plurality of grid indexes and historical data reported by each of the plurality of terminals in the cell comprises: the historical data comprising measurement report MRs and handover HO information; performing association filling processing on the historical data reported by each of the plurality of terminals in the cell by associating MRs and HO information successively reported by the same terminal and then filling the historical data according to preset filling rules; dividing the cell into the plurality of grids according to the plurality of grid indexes and the historical data after the association filling processing. dividing a cell into a plurality of grids according to a plurality of grid indexes and historical data reported by each of a plurality of terminals in the cell, wherein one grid index is used to uniquely identify one grid whereby the grid logically divides the cell based on a wireless communication characteristic of each terminal within the cell; performing (S 104) neighbor cell information statistics on each of a plurality of neighbor cells of the cell in each of the plurality of grids; and generating an effective radio frequency fingerprint database corresponding to the cell according to a result of the dividing and a result of the neighbor cell information statistics; wherein each of the plurality of grid indexes comprises a serving cell identification and serving cell quality; and dividing the cell into the plurality of grids according to the plurality of grid indexes and historical data reported by each of the plurality of terminals in the cell comprises: the historical data comprising measurement report MRs and handover HO information; performing association filling processing on the historical data reported by each of the plurality of terminals in the cell by associating MRs and HO information successively reported by the same terminal and then filling the historical data according to preset filling rules; dividing the cell into the plurality of grids according to the plurality of grid indexes and the historical data after the association filling processing. the historical data comprising measurement report MRs and handover HO information; performing association filling processing on the historical data reported by each of the plurality of terminals in the cell by associating MRs and HO information successively reported by the same terminal and then filling the historical data according to preset filling rules; dividing the cell into the plurality of grids according to the plurality of grid indexes and the historical data after the association filling processing.