mhurhangee/ep-ind-claims huggingface dataset:
Use of a sGC stimulator or activator selected from the group comprising 2-[1-(2-fluorobenzyl)-1 H-pyrazolo[3,4-b]pyridine-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamine, 2-[1-(2-fluorobenzyl)-1 H-pyrazolo[3,4-b]pyridine-3-yl]-5-(4-pyridinyl)-4-pyrimidinamine, methyl-4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-yl]-5-pyrimidinyl(methyl)carbamate, methyl-4,6-diamino-2-[1-(2-fluorobenzyl)-1 H-pyrazolo[3,4-b]pyridine-3-yl]-5-pyrimidinylcarbamate, 3-(4-amino-5-cyclopropylpyrimidine-2-yl)-1-(2-fluorobenzyl)1H-pyrazolo[3,4-b]pyridine, 5-chloro-2-(5-chlorothiophene-2-sulfonylamino-N-(4-(morpholine-4-sulfonyl)-phenyl)-benzamide sodium salt, 2-(4-chloro-phenylsulfonylamino)-4,5-dimethoxy-N-(4-(thiomorpholine-4-sulfonyl)-phenyl)-benzamide, and/or 4-({(4-carboxybutyl)[2-(2-{[4-(2-phenylethyl) benzyl] oxy}phenyl)ethyl]amino}methyl) benzoic acid, 1-{6-[5-chloro-2-({4-trans-4-}trifluoromethyl)cyclohexyl]benzyl}oxy)phenyl] pyridin-2-yl}-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid, 1-[6-(2-(2-methyl-4-(4-trifluoromethoxyphenyl)benzyloxy)-phenyl)pyridin-2-yl]-5-trifluoromethyl-pyrazole-4-carboxylic acid, 1[6-(3,4-dichlorophenyl)-2-pyridinyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid, 1-({2-[3-chloro-5-(trifluoromethyl)phenyl]-5-methyl-1,3-thiazol-4-yl}methyl)-1H-pyrazole-4-carboxylic acid, 4-({2-[3-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl}methyl)benzoic acid, 1-({2-[2-fluoro-3-(trifluoromethyl)phenyl]-5-methyl-1,3-thiazol-4-yl}methyl)-1H-pyrazole-4-carboxylic acid for the manufacture of a medicament for the treatment of Cystic Fibrosis.
A computing device comprising: at least one slot, the at least one slot that comprises a first locking element and a second locking element configured to receive a general purpose graphic processing unit (GPGPU) carrier; and the GPGPU carrier for removable insertion into the at least one slot, the GPGPU carrier comprising: a bracket comprising a first receiving space for securing a first GPGPU, a second receiving space for securing a second GPGPU, a first latching mechanism configured to secure the first locking element of the slot and a second latching mechanism configured to secure the second locking element of the slot, the GPGPU carrier being characterized by comprising: a frame secured to the bracket, wherein the frame comprises a first end, with a first guide slot and a second end with a second guide slot configured to secure the GPGPU carrier within the slot, wherein the first and second guide slots (107A, 107B) are configured to enable the GPGPU carrier to adjust from a first position to a second position while secured within the slot. at least one slot, the at least one slot that comprises a first locking element and a second locking element configured to receive a general purpose graphic processing unit (GPGPU) carrier; and the GPGPU carrier for removable insertion into the at least one slot, the GPGPU carrier comprising: a bracket comprising a first receiving space for securing a first GPGPU, a second receiving space for securing a second GPGPU, a first latching mechanism configured to secure the first locking element of the slot and a second latching mechanism configured to secure the second locking element of the slot, the GPGPU carrier being characterized by comprising: a frame secured to the bracket, wherein the frame comprises a first end, with a first guide slot and a second end with a second guide slot configured to secure the GPGPU carrier within the slot, wherein the first and second guide slots (107A, 107B) are configured to enable the GPGPU carrier to adjust from a first position to a second position while secured within the slot. a bracket comprising a first receiving space for securing a first GPGPU, a second receiving space for securing a second GPGPU, a first latching mechanism configured to secure the first locking element of the slot and a second latching mechanism configured to secure the second locking element of the slot, the GPGPU carrier being characterized by comprising: a frame secured to the bracket, wherein the frame comprises a first end, with a first guide slot and a second end with a second guide slot configured to secure the GPGPU carrier within the slot, wherein the first and second guide slots (107A, 107B) are configured to enable the GPGPU carrier to adjust from a first position to a second position while secured within the slot.
A sensor for determining a process variable in a container, the sensor comprising a housing and a process connection, the housing being rotatably arranged in the process connection in a connecting region, with the housing comprising a circumferential first groove on its outer circumference and the process connection comprising a circumferential second groove on its inner circumference, wherein the two grooves (28, 46) are arranged at a same height and thus merge radially into one another, and a fixing element is arranged in the cavity formed by the two grooves (28, 46), characterized in that the fixing element is either originally inserted into the second groove and then displaced inwards to achieve an assembled position, or is originally inserted into the first groove and then pulled outwards to achieve an assembled position, wherein, in the assembled position, the fixing element is located with a respective radial portion both in the first groove and in the second groove, and in that there is at least one radial screw for displacing or pulling the fixing element from its original position. characterized in that the fixing element is either originally inserted into the second groove and then displaced inwards to achieve an assembled position, or is originally inserted into the first groove and then pulled outwards to achieve an assembled position, wherein, in the assembled position, the fixing element is located with a respective radial portion both in the first groove and in the second groove, and in that there is at least one radial screw for displacing or pulling the fixing element from its original position.
A heat sink comprising: a heat sink body; the heat sink body comprises a structural heat sink body; a reflective layer disposed over the heat sink body that has reflectivity greater than 90% for light in the visible spectrum; a light transmissive protective layer disposed over the reflective layer that is light transmissive for light in the visible spectrum; characterized in that, a thermally conductive layer is disposed over the structural heat sink body, the thermally conductive layer has higher thermal conductivity than the structural heat sink body, the reflective layer is disposed over the thermally conductive layer. a heat sink body; the heat sink body comprises a structural heat sink body; a reflective layer disposed over the heat sink body that has reflectivity greater than 90% for light in the visible spectrum; a light transmissive protective layer disposed over the reflective layer that is light transmissive for light in the visible spectrum; a thermally conductive layer is disposed over the structural heat sink body, the thermally conductive layer has higher thermal conductivity than the structural heat sink body, the reflective layer is disposed over the thermally conductive layer.
A passive infra red detector comprising a plurality of passive infra red sensors (4, 5) and a lens member arranged to direct radiation from a target area onto the sensors (4, 5), wherein the detector comprises a first passive infra red sensor having a sensitive surface defining a first outward normal from said sensitive surface, and a plurality of second passive infra red sensors distributed about the first outward normal, wherein each second passive infra red sensor has a sensitive surface defining a second outward normal from the sensitive surface, wherein the second passive infra red sensors are inclined such that the second outward normal makes an acute angle with the first outward normal, wherein the lens member comprises a plurality of contiguous facets, each facet having an outer surface and an inner surface that forms a lens to direct radiation onto the sensors (4, 5), wherein the plurality of contiguous facets comprises a plurality of lenslets, wherein the lens member forms a substantially hemispherical dome about the infra red sensors (4,5); the dome has a central axis; the plurality of contiguous facets are distributed about the central axis; and the plurality of lenslets are distributed about the central axis; characterised in that: the first outward normal is aligned with the central axis of the dome; and an optical centre of each lenslet is located closer, along the surface of the dome, to the central axis than a geometrical centre of the area occupied by the lenslet. the first outward normal is aligned with the central axis of the dome; and an optical centre of each lenslet is located closer, along the surface of the dome, to the central axis than a geometrical centre of the area occupied by the lenslet.
Coupling device for mechanically coupling a fuel rail to a cylinder head of a combustion engine, the coupling device comprising - a holding fixture being designed to be mechanically coupled to the fuel rail and comprising a through hole extending between a first surface and a second surface, the second surface opposing the first surface and being arranged and designed to face the cylinder head, - a fastening element being designed to be fixedly coupled to the cylinder head, the fastening element comprising a head portion and a shank portion, the head portion facing the first surface of the holding fixture, the shank portion being partially arranged in the through hole and being designed to be in engagement with the cylinder head, and - a retaining element being arranged inside the through hole, being coupled with the holding fixture, comprising in a given latch area a cross-section restriction and being in engagement with the shank portion at least in this latch area, wherein the retaining element is formed as a one-piece unit, characterized in that the fastening element comprises a thread with a first thread section in a first area of the shank portion and a second thread section in a second area of the shank portion, wherein an intermediate area between the first and second area is shaped complementarily to the latch area of the retaining element. - a holding fixture being designed to be mechanically coupled to the fuel rail and comprising a through hole extending between a first surface and a second surface, the second surface opposing the first surface and being arranged and designed to face the cylinder head, - a fastening element being designed to be fixedly coupled to the cylinder head, the fastening element comprising a head portion and a shank portion, the head portion facing the first surface of the holding fixture, the shank portion being partially arranged in the through hole and being designed to be in engagement with the cylinder head, and - a retaining element being arranged inside the through hole, being coupled with the holding fixture, comprising in a given latch area a cross-section restriction and being in engagement with the shank portion at least in this latch area, wherein
Electric steering lock for a vehicle, in particular a motorised two-wheeler or three-wheeler, comprising: - a drive unit, - a locking bolt, - an actuator and - a control slot, which is mechanically coupled to the actuator in such a way that this latter is movable only in a specific steering angle range in a lifting axis in order to lock and to release a steering member by the locking bolt, characterised in that the actuator is movable only at a steering angle of ≥ 20° in two stages, wherein in a first position an ignition can be actuated and in a second position the locking or release of the locking bolt can be carried out, and that the actuator is movable relative to the control slide at a steering angle of < 20° only to the first position. - a drive unit, - a locking bolt, - an actuator and - a control slot, which is mechanically coupled to the actuator in such a way that this latter is movable only in a specific steering angle range in a lifting axis in order to lock and to release a steering member by the locking bolt,
A lighting module configured for the electrical connection to a conductive support comprising a plurality of conductive tracks extending along a longitudinal direction and spaced apart along a transverse direction, comprising: - a base, - at least one electrically powered light radiation source carried by said base, - a plurality of lamina electrical contacts (32', 32") connected to said source of light radiation and having respective proximal ends (34', 34") fixed to said base and respective distal ends (36', 36") elastically pressed against one face (28, 30) of said base, wherein said lamina electrical contacts (32', 32") are parallel and spaced apart along a longitudinal direction, wherein the distal ends (36', 36") of said lamina electrical contacts (32', 32") have respective contact areas (38', 38"), and wherein said contact areas (38', 38") are offset from each other in a transverse direction orthogonal to said longitudinal direction. - a base, - at least one electrically powered light radiation source carried by said base, - a plurality of lamina electrical contacts (32', 32") connected to said source of light radiation and having respective proximal ends (34', 34") fixed to said base and respective distal ends (36', 36") elastically pressed against one face (28, 30) of said base, wherein said lamina electrical contacts (32', 32") are parallel and spaced apart along a longitudinal direction, wherein the distal ends (36', 36") of said lamina electrical contacts (32', 32") have respective contact areas (38', 38"), and wherein said contact areas (38', 38") are offset from each other in a transverse direction orthogonal to said longitudinal direction.
An organ preservation system comprising: a cassette configured to hold an organ, said cassette coupled to a pump said pump comprising an outlet for providing a perfusate to the organ when the organ is received in said cassette and coupled to said pump, and an inlet for receiving the perfusate returning from the cassette; an actuator coupled to said pump to provide an actuating force to said pump; said pump configured to provide a pulsatile pumping force to the perfusate via a pumping stroke in response to said actuating force, said pumping stroke followed by a return stroke; said pumping stroke causing said pump to collapse to force a flow of the said perfusate through said outlet to the organ, said pump collapsing in a direction of the flow of the perfusate; said actuator coupled to said pump to retreate away from the pump to remove the actuating force from the pump; and said pump is elastically deformable such that the pump returns to the starting position during the return stroke, the pump avoiding being connected to the actuator; said return stroke allowing the perfusate to enter said pump through said inlet of the pump while avoiding sending fluid through the outlet. a cassette configured to hold an organ, said cassette coupled to a pump said pump comprising an outlet for providing a perfusate to the organ when the organ is received in said cassette and coupled to said pump, and an inlet for receiving the perfusate returning from the cassette; an actuator coupled to said pump to provide an actuating force to said pump; said pump configured to provide a pulsatile pumping force to the perfusate via a pumping stroke in response to said actuating force, said pumping stroke followed by a return stroke; said pumping stroke causing said pump to collapse to force a flow of the said perfusate through said outlet to the organ, said pump collapsing in a direction of the flow of the perfusate; said actuator coupled to said pump to retreate away from the pump to remove the actuating force from the pump; and said pump is elastically deformable such that the pump returns to the starting position during the return stroke, the pump avoiding being connected to the actuator; said return stroke allowing the perfusate to enter said pump through said inlet of the pump while avoiding sending fluid through the outlet.
A label assembly comprising: a top layer having a front side and a back side; an adhesive applied at the back side of the top layer, wherein the adhesive is a permanent adhesive; and a silicone-treated liner contacting the adhesive to sandwich the adhesive between the top layer and the silicone-treated liner, characterised in that the silicone-treated liner comprises paper that does not have a machine finish or gloss finish on a side of the paper that contacts the adhesive to allow at least a portion of the silicone to penetrate the paper and in that the silicone-treated liner includes a silicone treatment applied at the side of the paper that contacts the adhesive, the side of the paper that contacts the adhesive being an otherwise uncoated side of the paper. a top layer having a front side and a back side; an adhesive applied at the back side of the top layer, wherein the adhesive is a permanent adhesive; and a silicone-treated liner contacting the adhesive to sandwich the adhesive between the top layer and the silicone-treated liner, characterised in that the silicone-treated liner comprises paper that does not have a machine finish or gloss finish on a side of the paper that contacts the adhesive to allow at least a portion of the silicone to penetrate the paper and in that the silicone-treated liner includes a silicone treatment applied at the side of the paper that contacts the adhesive, the side of the paper that contacts the adhesive being an otherwise uncoated side of the paper.
Moisture sensor for monitoring an access to a patient for a system by which, via a flexible line, a liquid is fed to a patient and/or a liquid is fed out from the patient, the moisture sensor having a substrate material to be applied to the patient's skin, which has an electrically conductive structure which has conductor paths (L1, L2) arranged at a distance from one another which are connected together across a terminating resistor, the substrate material being a textile planar material in which the electrically conductive structure is embedded, and characterised in that the terminating resistor is an electrically conductive film which is applied in a section of the substrate material on which are formed electrical contacting portions (L2A, L1 B) for connecting the terminating resistor to the conductor paths (L1, L2).
A movable toy vehicle comprising a vehicle body, a chassis, a pair of front wheels (22, 24; 128; 130) and a pair of rear wheels (26, 28), a power source with at least one battery, a coil and a magnet for wheel steering control, a circuit for applying a current to the coil thereby to move the magnet, and wherein movement of the magnet is transmitted through a sliding plate to a steering mechanism thereby permitting steering the vehicle, wherein said coil is mounted on the vehicle chassis and said magnet is located inside the coil and is pivotable in relation to the coil transversely to the coil axis so that when the coil is energized by electric current, the magnetic field generated from the coil deflects the magnet to one side, characterized in that said magnet is attached to one end of a lever, said lever extends from said magnet, and the other end of said lever is shaped as a fork engaging a rod (116; 138) mounted on said sliding plate, whereby the deflection of said magnet caused by the application of a current to said coil results in a sliding movement of said sliding plate that is transferred to said steering mechanism for steering the vehicle.
An apparatus for marking a laboratory sample carrier, including: (i) a guide means configured to guide a sample carrier from an entry location to an exit location; and (ii) a marking means configured and positioned to mark a sample carrier at a marking location at a guide means position intermediate the entry and exit locations (6, 7), characterized in that the guide means is vertical or inclined such that a sample carrier can travel from the entry location to the exit location under the influence of gravity and the apparatus further includes selectively deployable first stop means for arresting the travel of a sample carrier down the guide means at the marking location, the first stop means being undeployable to allow the sample carrier to travel from the marking location to the exit location. (i) a guide means configured to guide a sample carrier from an entry location to an exit location; and (ii) a marking means configured and positioned to mark a sample carrier at a marking location at a guide means position intermediate the entry and exit locations (6, 7),
A fluid management and resection system (500, 510), comprising: an endoscope; a controller; a motorized tissue resecting probe operated by the controller; an inflow pump operated by the controller and configured to provide fluid inflow through a fluid flow path to a patient's body cavity; and an outflow pump operated by the controller and configured to provide fluid outflow through a fluid flow path from the body cavity; wherein the controller is configured to actuate the inflow pump and the outflow pump in response to a signal of fluid pressure in the body cavity to maintain a target pressure therein; wherein the signal of fluid pressure is provided by a pressure sensor coupled to a static fluid column within the endoscope communicating with the body cavity; wherein the pressure sensor includes two independent sensing elements (560', 560") that both interface with the static fluid column; characterized in that: the controller is further configured to provide a fluid loss warning if an inflow pump speed exceeds a predetermined level for a pre-selected time interval. an endoscope; a controller; a motorized tissue resecting probe operated by the controller; an inflow pump operated by the controller and configured to provide fluid inflow through a fluid flow path to a patient's body cavity; and an outflow pump operated by the controller and configured to provide fluid outflow through a fluid flow path from the body cavity; wherein the controller is configured to actuate the inflow pump and the outflow pump in response to a signal of fluid pressure in the body cavity to maintain a target pressure therein; wherein the signal of fluid pressure is provided by a pressure sensor coupled to a static fluid column within the endoscope communicating with the body cavity; wherein the pressure sensor includes two independent sensing elements (560', 560") that both interface with the static fluid column;
A method of interfacing a LC sensor with a control unit (280; 20), wherein said control unit (280; 20) comprises a first and a second contact, and wherein said LC sensor is connected between said first and said second contact, the method comprising the steps of starting the oscillation of said LC sensor and when said oscillation of said LC sensor is started: - monitoring the voltage ( V 204) at said second contact, said voltage ( V 204) at said second contact corresponding to the sum of the voltage ( V MID) at said first contact and the voltage ( V LC) at said LC sensor; and - varying the voltage ( V MID) at said first contact as a function of the voltage ( V 204) monitored at said second contact, such that the voltage ( V 204) at said second contact does not exceed an upper voltage threshold and does not fall below a lower voltage threshold. - monitoring the voltage ( V 204) at said second contact, said voltage ( V 204) at said second contact corresponding to the sum of the voltage ( V MID) at said first contact and the voltage ( V LC) at said LC sensor; and - varying the voltage ( V MID) at said first contact as a function of the voltage ( V 204) monitored at said second contact, such that the voltage ( V 204) at said second contact does not exceed an upper voltage threshold and does not fall below a lower voltage threshold.