A soft chewable composition for treating and/or preventing a parasitic infection or infestation in an animal, said composition comprising: (a) at least one isoxazoline active agent of Formula: and (b) a pharmaceutically acceptable carrier comprising: (i) one or more fillers, wherein said filler is soy protein fines, corn starch, or a mixture thereof; (ii) one or more solvents, wherein the solvent is selected from various grades of liquid polyethylene glycol; propylene carbonate; propylene glycol; triglycerides; sorbitol solution; glycerol caprylate/caprate; polyglycolized glycerides; and combinations thereof; (iii) one or more binders, wherein the binder is polyvinylpyrrolidone or a polyethylene glycol, or a combination thereof; (iv) one or more humectants, wherein the humectant is glycerol; (v) one or more surfactants selected from glyceryl monooleate, polyoxyethylene sorbitan fatty acid esters, sorbitan esters, polyvinyl alcohol, polysorbates, d -α-tocopheryl polyethylene glycol 1000 succinate (TPGS), sodium lauryl sulfate, co-polymers of ethylene oxide and propylene oxide, polyethylene glycol castor oil derivatives, propylene glycol monolaurate, glyceride esters, polyglycolized glycerides, PEG 300 caprylic/capric glycerides, PEG 400 caprylic/capric glycerides, PEG 300 oleic glycerides, PEG 300 linoleic glycerides, polyethylene glycol stearates and polyethylene glycol hydroxy stearates; and (vi) one or more flavoring agents. (a) at least one isoxazoline active agent of Formula: and (b) a pharmaceutically acceptable carrier comprising: (i) one or more fillers, wherein said filler is soy protein fines, corn starch, or a mixture thereof; (ii) one or more solvents, wherein the solvent is selected from various grades of liquid polyethylene glycol; propylene carbonate; propylene glycol; triglycerides; sorbitol solution; glycerol caprylate/caprate; polyglycolized glycerides; and combinations thereof; (iii) one or more binders, wherein the binder is polyvinylpyrrolidone or a polyethylene glycol, or a combination thereof; (iv) one or more humectants, wherein the humectant is glycerol; (v) one or more surfactants selected from glyceryl monooleate, polyoxyethylene sorbitan fatty acid esters, sorbitan esters, polyvinyl alcohol, polysorbates, d -α-tocopheryl polyethylene glycol 1000 succinate (TPGS), sodium lauryl sulfate, co-polymers of ethylene oxide and propylene oxide, polyethylene glycol castor oil derivatives, propylene glycol monolaurate, glyceride esters, polyglycolized glycerides, PEG 300 caprylic/capric glycerides, PEG 400 caprylic/capric glycerides, PEG 300 oleic glycerides, PEG 300 linoleic glycerides, polyethylene glycol stearates and polyethylene glycol hydroxy stearates; and (vi) one or more flavoring agents. (i) one or more fillers, wherein said filler is soy protein fines, corn starch, or a mixture thereof; (ii) one or more solvents, wherein the solvent is selected from various grades of liquid polyethylene glycol; propylene carbonate; propylene glycol; triglycerides; sorbitol solution; glycerol caprylate/caprate; polyglycolized glycerides; and combinations thereof; (iii) one or more binders, wherein the binder is polyvinylpyrrolidone or a polyethylene glycol, or a combination thereof; (iv) one or more humectants, wherein the humectant is glycerol; (v) one or more surfactants selected from glyceryl monooleate, polyoxyethylene sorbitan fatty acid esters, sorbitan esters, polyvinyl alcohol, polysorbates, d -α-tocopheryl polyethylene glycol 1000 succinate (TPGS), sodium lauryl sulfate, co-polymers of ethylene oxide and propylene oxide, polyethylene glycol castor oil derivatives, propylene glycol monolaurate, glyceride esters, polyglycolized glycerides, PEG 300 caprylic/capric glycerides, PEG 400 caprylic/capric glycerides, PEG 300 oleic glycerides, PEG 300 linoleic glycerides, polyethylene glycol stearates and polyethylene glycol hydroxy stearates; and (vi) one or more flavoring agents.