mhurhangee/ep-ind-claims huggingface dataset:
A magnetic resonance method comprising: at a magnetic resonance frequency of exchangeable protons of hydroxyl groups of a selected endogenous monosaccharide or polysaccharide, performing non-invasive in vivo magnetic labeling of hydroxyl protons of the selected endogenous monosaccharide or polysaccharide in a subject wherein the non-invasive magnetic labeling comprises applying a saturation pulse, inversion recovery pulse, or dephasing pulse to the hydroxyl proteins of the selected endogenous monosaccharide or polysaccharide in the subject; acquiring probative water proton magnetic resonance data in vivo while the in vivo non-invasive magnetic labeling is in effect; and deriving information about in vivo concentration of the selected endogenous monosaccharide or polysaccharide based at least on the probative water proton magnetic resonance data. at a magnetic resonance frequency of exchangeable protons of hydroxyl groups of a selected endogenous monosaccharide or polysaccharide, performing non-invasive in vivo magnetic labeling of hydroxyl protons of the selected endogenous monosaccharide or polysaccharide in a subject wherein the non-invasive magnetic labeling comprises applying a saturation pulse, inversion recovery pulse, or dephasing pulse to the hydroxyl proteins of the selected endogenous monosaccharide or polysaccharide in the subject; acquiring probative water proton magnetic resonance data in vivo while the in vivo non-invasive magnetic labeling is in effect; and deriving information about in vivo concentration of the selected endogenous monosaccharide or polysaccharide based at least on the probative water proton magnetic resonance data.
A pharmaceutical composition for use in the therapeutic treatment of muscle atrophy in an animal, the composition comprising a compound of formula: or a stereoisomer, tautomer, solvate, or pharmaceutically acceptable salt thereof. the composition comprising a compound of formula: or a stereoisomer, tautomer, solvate, or pharmaceutically acceptable salt thereof.
A method for producing a benzaldehyde in which an amino group is bonded in a 2 position, a halogeno group or an alkoxy group is bonded in a 3 position, and a hydrogen atom, an alkyl group, a halogeno group, an alkoxy group, or a cyano group is bonded independently in each of 4, 5, and 6 positions, the method comprising: preparing a benzaldehyde in which the halogeno group or the alkoxy group is bonded in the 3 position, a hydrogen atom is bonded in the 2 position, and the hydrogen atom, the alkyl group, the halogeno group, the alkoxy group, or the cyano group is bonded independently in each of the 4, 5, and 6 positions so that a lithiation reaction is most active at the 2 position (hereinafter, abbreviated as 2-unsubstituted benzaldehyde); acetal-protecting a formyl group in the 2-unsubstituted benzaldehyde; sequentially performing lithiation, azidation, and amination of the 2 position; and subsequently performing acetal deprotection, wherein the 2-unsubstituted benzaldehyde is a compound of formula: wherein in the formula R 3 represents a halogeno group or an alkoxy group, R 4, R 5, and R 6 each independently represent a hydrogen atom, an alkyl group, a halogeno group, an alkoxy group, or a cyano group, wherein in a case where R 4 is a hydrogen atom, R 5 is a hydrogen atom, an alkyl group, or a cyano group, in a case where R 5 is a hydrogen atom, at least one of R 4 and R 6 is a hydrogen atom, an alkyl group, or a cyano group, and in a case where R 6 is a hydrogen atom, R 5 is a hydrogen atom, an alkyl group, or a cyano group. preparing a benzaldehyde in which the halogeno group or the alkoxy group is bonded in the 3 position, a hydrogen atom is bonded in the 2 position, and the hydrogen atom, the alkyl group, the halogeno group, the alkoxy group, or the cyano group is bonded independently in each of the 4, 5, and 6 positions so that a lithiation reaction is most active at the 2 position (hereinafter, abbreviated as 2-unsubstituted benzaldehyde); acetal-protecting a formyl group in the 2-unsubstituted benzaldehyde; sequentially performing lithiation, azidation, and amination of the 2 position; and subsequently performing acetal deprotection, R 3 represents a halogeno group or an alkoxy group, R 4, R 5, and R 6 each independently represent a hydrogen atom, an alkyl group, a halogeno group, an alkoxy group, or a cyano group, wherein in a case where R 4 is a hydrogen atom, R 5 is a hydrogen atom, an alkyl group, or a cyano group, in a case where R 5 is a hydrogen atom, at least one of R 4 and R 6 is a hydrogen atom, an alkyl group, or a cyano group, and in a case where R 6 is a hydrogen atom, R 5 is a hydrogen atom, an alkyl group, or a cyano group.
A method of joining a first component to a second component comprising: selecting at least one material for a filler material; applying the filler material to an interface surface of the first component; providing a spray nozzle; characterized in that said method Further comprises deriving, prior to initiating deposition of said filler material, a nozzle path across the interface surface, a travel speed of said nozzle over said nozzle path and a spray distance for said nozzle path; depositing said at least one filler material in solid particle form from said nozzle onto the interface surface so that said filler material plastically deforms without melting and bonds to the interface surface upon impact with the interface surface; and said depositing step comprising controlling a transition rate and an orientation of said nozzle so as to achieve a uniform filler material thickness on said interface surface; and joining said first component to a second component wherein said joining step comprises holding said first and second components (101, 103) in a fixture and applying heat to said first and second components (101, 103) and said heat said depositing step comprising controlling a transition rate and an orientation of said nozzle so as to achieve a uniform filler material thickness on said interface applying step comprises heating said first and second components (101, 103) to a temperature above the temperature at which the filler material turns liquid. selecting at least one material for a filler material; applying the filler material to an interface surface of the first component; providing a spray nozzle; characterized in that said method Further comprises deriving, prior to initiating deposition of said filler material, a nozzle path across the interface surface, a travel speed of said nozzle over said nozzle path and a spray distance for said nozzle path; depositing said at least one filler material in solid particle form from said nozzle onto the interface surface so that said filler material plastically deforms without melting and bonds to the interface surface upon impact with the interface surface; and said depositing step comprising controlling a transition rate and an orientation of said nozzle so as to achieve a uniform filler material thickness on said interface surface; and joining said first component to a second component wherein said joining step comprises holding said first and second components (101, 103) in a fixture and applying heat to said first and second components (101, 103) and said heat said depositing step comprising controlling a transition rate and an orientation of said nozzle so as to achieve a uniform filler material thickness on said interface applying step comprises heating said first and second components (101, 103) to a temperature above the temperature at which the filler material turns liquid.
A bleeding method for a round fish, comprising: step of forming a slit that connects a pericardial cavity to an outer part of the fish by cutting a membrane of gill to split a head and an abdomen such that an abdominal aorta is not cut and internal organs incorporated in an abdominal cavity are not exposed to an outside air, step of spreading the slit such that an arterial sphere of the fish is not pulled up together with flesh on an abdominal side being lifted, and a caudal side surface of a ventricle in a heart of the fish is exposed, step of inserting a tubular instrument in the heart of the fish, which runs through the slit from the caudal side surface of the ventricle toward the arterial sphere, step of fixing the tubular instrument to the heart, and step of discharging blood of the fish outside by press-fitting liquid into vascular system of the fish via the tubular instrument. step of forming a slit that connects a pericardial cavity to an outer part of the fish by cutting a membrane of gill to split a head and an abdomen such that an abdominal aorta is not cut and internal organs incorporated in an abdominal cavity are not exposed to an outside air, step of spreading the slit such that an arterial sphere of the fish is not pulled up together with flesh on an abdominal side being lifted, and a caudal side surface of a ventricle in a heart of the fish is exposed, step of inserting a tubular instrument in the heart of the fish, which runs through the slit from the caudal side surface of the ventricle toward the arterial sphere, step of fixing the tubular instrument to the heart, and step of discharging blood of the fish outside by press-fitting liquid into vascular system of the fish via the tubular instrument.
Compression garment for a limb of a person, comprising a flexible body portion having a first, limbward side and a second side opposing the first side, and at least one band extending from a lateral side of the body portion for wrapping around the limb, wherein the band comprises a fastener such that the end of the band is removably attachable onto the compression garment when wrapped around the limb, wherein the fastener of the band comprises a loop portion on the outer side and a hook portion, which is provided at the end of the band, on the inner side to attach the band at variable positions onto itself and the body portion further comprises at least one guiding element providing a channel for receiving the band and guiding the band back over itself when the band spans over the first side to provide an opening for receiving the limb, such that the channel guides the tensioning, direction, and placement of the at least one band, characterised in that the guiding element is an elongate guiding sleeve and comprises a folded-over section of the body portion fastened back onto the body portion to form the channel.
A gas turbine engine vane, the vane comprising an airfoil section that is hollow and includes an internal passage, and a ceramic wall defining at least a side of the passage, the ceramic wall including a flow turbulator that projects into the passage, wherein the ceramic wall includes a body portion from which the flow turbulators project, and the body portion is formed of ceramic matrix composite having a plurality of fibers disposed in a ceramic matrix, characterised in that the flow turbulator is formed of ceramic matrix composite, the ceramic matrix composite of the flow turbulator includes a plurality of fibers disposed in a ceramic matrix, the fibers of the body portion have a common body fiber orientation, and the fibers of the flow turbulator have a common turbulator fiber orientation that is transverse to the common body fiber orientation.
A ventilation member to be attached to a through hole of a housing, comprising: a main body unit provided with a ventilation path that forms a flow path for gas between an interior and an exterior of the housing; a sealing unit that seals between the main body unit and the housing; a ventilation membrane unit provided on the ventilation path to prevent passage of a liquid and a solid and to allow passage of gas; and a surrounding unit that is provided in the main body unit and surrounds an end portion opening of the ventilation path having a height uniformly formed, wherein an end portion opening forms a termination of the ventilation path on the outside of the housing, and the end portion opening opens while facing toward an intersecting direction that intersects an attachment surface on which the through hole is formed in the housing for attaching the ventilation member, wherein the surrounding unit is protruded in the intersecting direction and most towards the outside of the end portion opening, characterised in that the sealing unit includes an opening portion inside thereof, at least a part of the ventilation membrane unit is provided inside the opening portion, and the ventilation membrane unit is disposed within a range of a width region of the sealing unit in the intersecting direction. a main body unit provided with a ventilation path that forms a flow path for gas between an interior and an exterior of the housing; a sealing unit that seals between the main body unit and the housing; a ventilation membrane unit provided on the ventilation path to prevent passage of a liquid and a solid and to allow passage of gas; and a surrounding unit that is provided in the main body unit and surrounds an end portion opening of the ventilation path having a height uniformly formed, wherein an end portion opening forms a termination of the ventilation path on the outside of the housing, and the end portion opening opens while facing toward an intersecting direction that intersects an attachment surface on which the through hole is formed in the housing for attaching the ventilation member, wherein the surrounding unit is protruded in the intersecting direction and most towards the outside of the end portion opening, characterised in that the sealing unit includes an opening portion inside thereof, at least a part of the ventilation membrane unit is provided inside the opening portion, and the ventilation membrane unit is disposed within a range of a width region of the sealing unit in the intersecting direction.
An invasive instrument extending in a longitudinal direction, having a tip section at a distal end, a steering section at a proximal end and a body section between the tip section and the steering section, the invasive instrument comprises steering wires (16(i)) extending from the steering section to the tip section and configured to deflect at least a first portion of the tip section by a longitudinal movement of the one or more steering wires (16(i)), one or more longitudinal actuation elements (608; 826; 934, 962; 2; 5006) provided with at least one component (622; 624; 636; 638; 640; 687; 693; 936, 938, 964, 966; 1042; 1204; 1308, 1310; 1338) configured to transform a longitudinal movement of the one or more longitudinal actuation elements (606; 608; 826; 934, 962; 2; 5006) into a tangential movement of at least one of: a. one or more movable elements such that they operate as a locking element (416(m); 516, 704; 716; 718; 734/736; 746/748; 756/758; 1002; 1107/1108) in order to either freeze a deflected or non-deflected condition of a flexible portion of the invasive instrument or limit deflection of the flexible portion of the invasive instrument, b. at least one of one or more mechanical switches and the one or more steering wires (16(i)), whereby the one or more steering wires (16(i)) are either fixed to a fixed element, coupled to another movable element, limited in their movement, only capable of moving under friction, coupled to one out of different steering units in the steering section, uncoupled from a steering unit in the steering section or released to a free floating condition, or c. one or more switching elements (1201/1208; 1304; 1306; 1336) configured to couple two adjacent movable elements (1214(s); 1316(s)) such that they can move together, the one or more movable elements (416(m); 516, 704; 716; 718; 734/736; 746/748; 756/758; 1002; 1107/1108; 16(i); 1214(s); 1316(s)), the one or more steering wires (16(i)), the one or more switching elements and one or more longitudinal actuation elements (608; 826; 934, 962; 2) being all portions of one or more tubes inserted into one another. a. one or more movable elements such that they operate as a locking element (416(m); 516, 704; 716; 718; 734/736; 746/748; 756/758; 1002; 1107/1108) in order to either freeze a deflected or non-deflected condition of a flexible portion of the invasive instrument or limit deflection of the flexible portion of the invasive instrument, b. at least one of one or more mechanical switches and the one or more steering wires (16(i)), whereby the one or more steering wires (16(i)) are either fixed to a fixed element, coupled to another movable element, limited in their movement, only capable of moving under friction, coupled to one out of different steering units in the steering section, uncoupled from a steering unit in the steering section or released to a free floating condition, or c. one or more switching elements (1201/1208; 1304; 1306; 1336) configured to couple two adjacent movable elements (1214(s); 1316(s)) such that they can move together,
A battery, comprising a cell and an electrolyte, the cell comprising a positive electrode plate, comprising - a positive electrode current collector and - a positive electrode film disposed on at least one surface of the positive electrode current collector and comprised of a positive electrode active material; a negative electrode plate, comprising - a negative electrode current collector and - a negative electrode film disposed on at least one surface of the negative electrode current collector and comprised of a negative electrode active material; and a separator, disposed between the positive electrode plate and the negative electrode plate; characterized in that, in the battery, at least one surface of the positive electrode film and/or the negative electrode film is provided with protrusions; and the battery satisfies following condition: 0.4≤(T c +T a)/(H c +H a)≤0.8, where T c is a height of the protrusions provided on the at least one surface of the positive electrode film; T a is a height of protrusions provided on the at least one surface of the negative electrode film; H c is a thickness increase of the positive electrode film when the battery has a 100% SOC for a first time; and H a is a thickness increase of the negative electrode film when the battery has a 100% SOC for a first time. a positive electrode plate, comprising - a positive electrode current collector and - a positive electrode film disposed on at least one surface of the positive electrode current collector and comprised of a positive electrode active material; - a positive electrode current collector and - a positive electrode film disposed on at least one surface of the positive electrode current collector and comprised of a positive electrode active material; a negative electrode plate, comprising - a negative electrode current collector and - a negative electrode film disposed on at least one surface of the negative electrode current collector and comprised of a negative electrode active material; - a negative electrode current collector and - a negative electrode film disposed on at least one surface of the negative electrode current collector and comprised of a negative electrode active material; and a separator, disposed between the positive electrode plate and the negative electrode plate; characterized in that, in the battery, at least one surface of the positive electrode film and/or the negative electrode film is provided with protrusions; and the battery satisfies following condition: 0.4≤(T c +T a)/(H c +H a)≤0.8, where T c is a height of the protrusions provided on the at least one surface of the positive electrode film; T a is a height of protrusions provided on the at least one surface of the negative electrode film; H c is a thickness increase of the positive electrode film when the battery has a 100% SOC for a first time; and H a is a thickness increase of the negative electrode film when the battery has a 100% SOC for a first time.
An ultrasonic flow measurement system, comprising: - a flow tube as a continuous flow tube for fluid whose flow rate is to be determined - an ultrasound damping layer, provided at an outer side of the flow tube and substantially surrounding said flow tube, the speed of sound in the material of the flow tube being higher than the speed of sound in the material of the ultrasound damping layer; - an ultrasound transmitter, arranged on the outer side of the flow tube and covered by the ultrasound damping layer, the ultrasound transmitter being configured to transmit ultrasound signals through said fluid in a transmitting phase, wherein on the interface of the flow tube and the ultrasound damping layer Stoneley waves appear and - an ultrasound receiver, arranged on the outer side of the flow tube and covered by the ultrasound damping layer, the ultrasound receiver being configured to receive transmitted ultrasound signals in a receiving phase, characterised in that the ultrasound damping layer comprises: - a first damping portion that is at least partially positioned in between the ultrasound transmitter and the ultrasound receiver as well as - a second damping portion that is at least partially positioned in between the ultrasound transmitter and the ultrasound receiver, wherein the first damping portion and the second damping portion of the ultrasound damping layer are spaced apart from each other by a section, gap or void over a distance (d) in an axial direction of the flow tube, wherein the section, gap or void prevents the Stoneley waves, or at least a significant part thereof, from reaching the ultrasound receiver after they are transmitted by the ultrasound transmitter. - a flow tube as a continuous flow tube for fluid whose flow rate is to be determined - an ultrasound damping layer, provided at an outer side of the flow tube and substantially surrounding said flow tube, the speed of sound in the material of the flow tube being higher than the speed of sound in the material of the ultrasound damping layer; - an ultrasound transmitter, arranged on the outer side of the flow tube and covered by the ultrasound damping layer, the ultrasound transmitter being configured to transmit ultrasound signals through said fluid in a transmitting phase, wherein on the interface of the flow tube and the ultrasound damping layer Stoneley waves appear and - an ultrasound receiver, arranged on the outer side of the flow tube and covered by the ultrasound damping layer, the ultrasound receiver being configured to receive transmitted ultrasound signals in a receiving phase, characterised in that the ultrasound damping layer comprises: - a first damping portion that is at least partially positioned in between the ultrasound transmitter and the ultrasound receiver as well as - a second damping portion that is at least partially positioned in between the ultrasound transmitter and the ultrasound receiver,