A method of operation of a node (12, 14) associated with a cellular communications network, comprising: making a determination to trigger interference mitigation at a wireless device when predefined criteria are satisfied, the predefined criteria being based on a signal load or interference level in at least one interfering cell from which transmissions result in interference at the wireless device during reception from a desired cell, a relation between reference signals used in the desired cell and the at least one interfering cell, and a timing relation between signals transmitted by the desired cell and signals transmitted by the at least one interfering cell, and/or signals received at the wireless device from the desired cell and signals received at the wireless device from the at least one interfering cell, the timing relation defining a maximum absolute deviation in frame start timing between the desired cell and the at least one interfering cell, wherein the predefined criteria comprise: a first criterion that the relation between the reference signals used in the desired cell and the at least one interfering cell be non-colliding, wherein the non-colliding reference signals do not overlap in time and frequency; and a second criterion that the signal load in the at least one interfering cell be less than a predetermined threshold; and triggering interference mitigation at the wireless device in response to making the determination to trigger interference mitigation at the wireless device. making a determination to trigger interference mitigation at a wireless device when predefined criteria are satisfied, the predefined criteria being based on a signal load or interference level in at least one interfering cell from which transmissions result in interference at the wireless device during reception from a desired cell, a relation between reference signals used in the desired cell and the at least one interfering cell, and a timing relation between signals transmitted by the desired cell and signals transmitted by the at least one interfering cell, and/or signals received at the wireless device from the desired cell and signals received at the wireless device from the at least one interfering cell, the timing relation defining a maximum absolute deviation in frame start timing between the desired cell and the at least one interfering cell, wherein the predefined criteria comprise: a first criterion that the relation between the reference signals used in the desired cell and the at least one interfering cell be non-colliding, wherein the non-colliding reference signals do not overlap in time and frequency; and a second criterion that the signal load in the at least one interfering cell be less than a predetermined threshold; and a first criterion that the relation between the reference signals used in the desired cell and the at least one interfering cell be non-colliding, wherein the non-colliding reference signals do not overlap in time and frequency; and a second criterion that the signal load in the at least one interfering cell be less than a predetermined threshold; and triggering interference mitigation at the wireless device in response to making the determination to trigger interference mitigation at the wireless device.