Structural facade comprising at least two cells for buildings and the like, comprising - a structural frame having a pair of uprights and a pair of crossbeams so as to form a structure closed around the perimeter delimiting a perimetral compartment, the perimetral compartment being suitable to be closed by external glazing mechanically associated to the frame on an anterior face of the latter, wherein - said uprights and crossbeams comprise a load-bearing metallic core which supports and lends structural rigidity to the cell, - the metallic core comprises means of attachment, such as screws, pins, wall plugs and similar, for the support and attachment of the external glazing to the structural frame, the means of attachment being positioned on the side opposite the perimetral compartment, wherein the cells are placed alongside at their respective uprights and/or crossbeams adjacent to each other and connected to each other by joints fitted with undercuts in an axial direction (Z-Z) perpendicular to the associable glazing, characterised in that - said uprights and crossbeams each comprising at least one cheek panel in wood, directly facing said perimetral compartment, on the side opposite the means of attachment of the external glazing, - the cheek panel being bound to the metallic core of the crossbeams and of the uprights by means of shaped couplings and gluing means, - the cheek panel covering the metallic core on the side of the perimetral compartment and on a rear face of the frame, opposite the associable glazing, so as to increase the resistance to fire of the system, as well as the heat and noise insulation, wherein the shaped coupling means comprise joints between at least one protuberance made on the metallic core and at least one groove, counter-shaped to the protuberance, made on an inner face of the cheek panel, directly facing the metallic core, wherein between an inner face of the cheek panel, directly facing the metallic core and the metallic core itself, a chamber containing said gluing means able to glue and seal the cheek panel and metallic core to each other is defined, wherein said chamber has a constant predefined thickness and the gluing means have a higher elasticity modulus than the materials of the cheek panel and the metallic core so as to allow and absorb the different dilations of the two coupled materials. - a structural frame having a pair of uprights and a pair of crossbeams so as to form a structure closed around the perimeter delimiting a perimetral compartment, the perimetral compartment being suitable to be closed by external glazing mechanically associated to the frame on an anterior face of the latter, wherein - said uprights and crossbeams comprise a load-bearing metallic core which supports and lends structural rigidity to the cell, - the metallic core comprises means of attachment, such as screws, pins, wall plugs and similar, for the support and attachment of the external glazing to the structural frame, the means of attachment being positioned on the side opposite the perimetral compartment, wherein the cells are placed alongside at their respective uprights and/or crossbeams adjacent to each other and connected to each other by joints fitted with undercuts in an axial direction (Z-Z) perpendicular to the associable glazing, characterised in that - said uprights and crossbeams each comprising at least one cheek panel in wood, directly facing said perimetral compartment, on the side opposite the means of attachment of the external glazing, - the cheek panel being bound to the metallic core of the crossbeams and of the uprights by means of shaped couplings and gluing means, - the cheek panel covering the metallic core on the side of the perimetral compartment and on a rear face of the frame, opposite the associable glazing, so as to increase the resistance to fire of the system, as well as the heat and noise insulation, wherein the shaped coupling means comprise joints between at least one protuberance made on the metallic core and at least one groove, counter-shaped to the protuberance, made on an inner face of the cheek panel, directly facing the metallic core, wherein between an inner face of the cheek panel, directly facing the metallic core and the metallic core itself, a chamber containing said gluing means able to glue and seal the cheek panel and metallic core to each other is defined, wherein said chamber has a constant predefined thickness and the gluing means have a higher elasticity modulus than the materials of the cheek panel and the metallic core so as to allow and absorb the different dilations of the two coupled materials.