A straddle-type multimodal transportation interworking system, comprising a rail system, a cargo vehicle, a transfer apparatus and a processor, wherein the cargo vehicle is movably provided on a rail beam of the rail system, wherein two ends of the cargo vehicle in a running direction thereof are provided with anti-collision devices which are disposed at two opposite ends of a train frame; the transfer apparatus is used for transferring a goods loading device from a transportation tool to the cargo vehicle and loading the goods loading device onto the cargo vehicle, or unloading the goods loading device from the cargo vehicle and conveying the goods loading device onto the transportation tool; the processor is connected to the cargo vehicle and the transfer apparatus so as to control the transfer apparatus to transfer the goods loading device, and to control the cargo vehicle to move on the rail beam after the goods loading device is secured onto the cargo vehicle; wherein, as the goods loading device needs to be transferred, the transfer apparatus transfers the goods loading device from the transportation tool to the cargo vehicle and loads the goods loading device onto the cargo vehicle, and the processor controls the cargo vehicle to move on the rail beam, or the transfer apparatus unloads the goods loading device from the cargo vehicle and conveys the goods loading device onto the transportation tool; characterised in that the cargo vehicle comprises: a base frame, at least two travelling wheels, at least two guide wheels, a travelling-driving device, a train frame and an elastic member; the at least two travelling wheels are rotatably disposed on the base frame and can rotate on an upper surface of the rail beam; the at least two guide wheels are rotatably disposed on the base frame and come into contact with two side surfaces of a travel rail of the rail beam respectively; the travelling-driving device is fixed onto the base frame and is connected to the at least two travelling wheels for driving the at least two travelling wheels to rotate; the elastic member is fixed onto the base frame; and the train frame is disposed on the elastic member. the cargo vehicle is movably provided on a rail beam of the rail system, wherein two ends of the cargo vehicle in a running direction thereof are provided with anti-collision devices which are disposed at two opposite ends of a train frame; the transfer apparatus is used for transferring a goods loading device from a transportation tool to the cargo vehicle and loading the goods loading device onto the cargo vehicle, or unloading the goods loading device from the cargo vehicle and conveying the goods loading device onto the transportation tool; the processor is connected to the cargo vehicle and the transfer apparatus so as to control the transfer apparatus to transfer the goods loading device, and to control the cargo vehicle to move on the rail beam after the goods loading device is secured onto the cargo vehicle; wherein, as the goods loading device needs to be transferred, the transfer apparatus transfers the goods loading device from the transportation tool to the cargo vehicle and loads the goods loading device onto the cargo vehicle, and the processor controls the cargo vehicle to move on the rail beam, or the transfer apparatus unloads the goods loading device from the cargo vehicle and conveys the goods loading device onto the transportation tool; characterised in that the cargo vehicle comprises: a base frame, at least two travelling wheels, at least two guide wheels, a travelling-driving device, a train frame and an elastic member; the at least two travelling wheels are rotatably disposed on the base frame and can rotate on an upper surface of the rail beam; the at least two guide wheels are rotatably disposed on the base frame and come into contact with two side surfaces of a travel rail of the rail beam respectively; the travelling-driving device is fixed onto the base frame and is connected to the at least two travelling wheels for driving the at least two travelling wheels to rotate; the elastic member is fixed onto the base frame; and the train frame is disposed on the elastic member.