A balloon catheter comprising: a main catheter shaft including a first guidewire lumen (706A, a second guidewire lumen, and an inflation lumen; a balloon extending from a distal end of the main catheter shaft, wherein the inflation lumen of the main catheter shaft is in fluid communication with an interior of the balloon; a first deformable guidewire shaft extending from a distal end of the main catheter shaft, adjacent and external to the balloon, wherein the first deformable guidewire shaft defines a lumen in fluid communication with the first guidewire lumen of the main catheter shaft; a second deformable guidewire shaft extending from a distal end of the main catheter shaft, adjacent and external to the balloon, wherein the second deformable guidewire shaft defines a lumen in fluid communication with the second guidewire lumen of the main catheter shaft; a proximal bond that fixes a proximal end of the balloon to a distal end of the main catheter shaft; a first distal bond that fixes a distal end of the balloon to a first distal end of the first deformable guidewire shaft and a second distal bond that fixes the first distal end of the first deformable guidewire shaft to a second distal end of the second deformable guidewire shaft; at least one intermediate bond that fixes an intermediate portion of the balloon to an intermediate portion of the second deformable guidewire shaft, wherein an outer surface of the first deformable guidewire shaft between the proximal bond and the first distal bond is not bonded to the balloon, and wherein the balloon inflation causes the balloon and the first deformable guidewire shaft to bend in radially opposing directions and causes the balloon and the second deformable guidewire shaft to bend in the same direction, thereby orienting the distal ends of the first and second deformable guidewire shafts in directions different from that of the main catheter shaft. a main catheter shaft including a first guidewire lumen (706A, a second guidewire lumen, and an inflation lumen; a balloon extending from a distal end of the main catheter shaft, wherein the inflation lumen of the main catheter shaft is in fluid communication with an interior of the balloon; a first deformable guidewire shaft extending from a distal end of the main catheter shaft, adjacent and external to the balloon, wherein the first deformable guidewire shaft defines a lumen in fluid communication with the first guidewire lumen of the main catheter shaft; a second deformable guidewire shaft extending from a distal end of the main catheter shaft, adjacent and external to the balloon, wherein the second deformable guidewire shaft defines a lumen in fluid communication with the second guidewire lumen of the main catheter shaft; a proximal bond that fixes a proximal end of the balloon to a distal end of the main catheter shaft; a first distal bond that fixes a distal end of the balloon to a first distal end of the first deformable guidewire shaft and a second distal bond that fixes the first distal end of the first deformable guidewire shaft to a second distal end of the second deformable guidewire shaft; at least one intermediate bond that fixes an intermediate portion of the balloon to an intermediate portion of the second deformable guidewire shaft, wherein an outer surface of the first deformable guidewire shaft between the proximal bond and the first distal bond is not bonded to the balloon, and wherein the balloon inflation causes the balloon and the first deformable guidewire shaft to bend in radially opposing directions and causes the balloon and the second deformable guidewire shaft to bend in the same direction, thereby orienting the distal ends of the first and second deformable guidewire shafts in directions different from that of the main catheter shaft.