mhurhangee/ep-ind-claims huggingface dataset:
Variant of a parent polypeptide comprising an Fc fragment, wherein the variant has an increased affinity for at least one of the Fc (FcR) fragment receptors selected from among FcγRllla (CD16a), FcγRlla (CD32a) and FcγRllb (CD32b) receptors, relative to that of the parent polypeptide, characterized in that it comprises at least the mutation Y296W of the Fc fragment; and either: (ii) a mutation selected from among 378V, 378T, 434Y and 434S; and (iii) at least one mutation selected from among 226G, P228L, P228R, 230S, 230T, 230L, 241L, 264E, 307P, 315D, 330V, 362R, 378V, 378T, 389T, 389K, 434Y and 434S, with the condition that mutations (ii) and (iii) do not occur on the same amino acids, or: (iv) a mutation selected from among 307N, 326E, 326T, 334N, 334R, 352L, 378V, 378T, 394P, 396L, 397M, and 421T; and (v) at least one mutation selected from among 226Y, 227S, 230S, 231V, 234P, 243I, 243L, 246R, 246E, 247T, 248E, 253F, 254F, 255W, 259A, 261R, 262A, 263A, 266M, 267N, 267G, 274E, 274R, 276S, 278H, 282A, 283G, 284L, 2861, 286Y, 287T, 288E, 288R, 290E, 298N, 302A, 305A, 307P, 308A, 308I, 308G, 309P, 312G, 315D, 316D, 319H, 320T, 320R, 320M, 322E, 323I, 325S, 333G, 334N, 334R, 336T, 339T, 340E, 343S, 345G, 349S, 349H, 350A 352S, 359A, 361H, 362R, 363I, 366A, 373D, 375R, 377T, 378V, 378T, 379A, 380G, 383R, 385R, 389S, 389T, 392R, 393A, 393I, 394P, 396L, 397I, 397M, 398P, 405V, 405L, 410R, 412M, 414R, 421T, 421S, 423L, 423Y, 423S, 423P, 428T, 431V, 431T, 434K, 434S, 435R, 436H, 439R, 440G, 440N, 442F, 442P and 447N, with the condition that the mutations (iv) and (v) do not occur on the same amino acids, the numbering being that of the EU index or equivalent in Kabat. (ii) a mutation selected from among 378V, 378T, 434Y and 434S; and (iii) at least one mutation selected from among 226G, P228L, P228R, 230S, 230T, 230L, 241L, 264E, 307P, 315D, 330V, 362R, 378V, 378T, 389T, 389K, 434Y and 434S, with the condition that mutations (ii) and (iii) do not occur on the same amino acids, (iv) a mutation selected from among 307N, 326E, 326T, 334N, 334R, 352L, 378V, 378T, 394P, 396L, 397M, and 421T; and (v) at least one mutation selected from among 226Y, 227S, 230S, 231V, 234P, 243I, 243L, 246R, 246E, 247T, 248E, 253F, 254F, 255W, 259A, 261R, 262A, 263A, 266M, 267N, 267G, 274E, 274R, 276S, 278H, 282A, 283G, 284L, 2861, 286Y, 287T, 288E, 288R, 290E, 298N, 302A, 305A, 307P, 308A, 308I, 308G, 309P, 312G, 315D, 316D, 319H, 320T, 320R, 320M, 322E, 323I, 325S, 333G, 334N, 334R, 336T, 339T, 340E, 343S, 345G, 349S, 349H, 350A 352S, 359A, 361H, 362R, 363I, 366A, 373D, 375R, 377T, 378V, 378T, 379A, 380G, 383R, 385R, 389S, 389T, 392R, 393A, 393I, 394P, 396L, 397I, 397M, 398P, 405V, 405L, 410R, 412M, 414R, 421T, 421S, 423L, 423Y, 423S, 423P, 428T, 431V, 431T, 434K, 434S, 435R, 436H, 439R, 440G, 440N, 442F, 442P and 447N, with the condition that the mutations (iv) and (v) do not occur on the same amino acids, the numbering being that of the EU index or equivalent in Kabat.
Lift unit for a passenger boarding bridge, comprising - a cross member, - two elevating posts, mounted at two opposite ends (L, R) of the cross member, each elevating post comprising a lower tube and an upper tube, which can be telescoped by means of an actuating device, in particular a hydraulic device, the lower tube is adapted to being supported by the cross member, the upper tube is adapted to carry a tunnel of the passenger boarding bridge, the cross member comprises a cross-member-side support defining a plurality of support positions, at which a tube-side support can be attached, characterized in that the cross-member-side support comprises a plurality of mounting holes, arranged side-by-side, wherein a variety of different selections of the mounting holes each defining a respective support position, and that the cross-member-side support comprises at least at one end (L, R), in particular at both ends, more mounting holes - than required by the tube-side support, and/or - than fixing holes are provided at the respective tube-side support. - a cross member, - two elevating posts, mounted at two opposite ends (L, R) of the cross member, - than required by the tube-side support, and/or - than fixing holes are provided at the respective tube-side support.
Wireless high-throughput communication system for a structure and a vehicle parked in front of said structure, said assembly comprising a first communication device and a first computer system, said first communication device and said first computer system belonging to a vehicle, and a second communication device and a second computer system, said second communication device and said second computer system belonging to a structure that is separate from said vehicle, in order to allow data to be exchanged between said first and second computer systems via high-throughput wireless communication between said first and second communication devices, each of said first and second communication devices respectively comprising at least one first, one second antenna (115, 120) and at least one first, one second transmitter/receiver (610, 630) respectively connected to said at least one first, one second antenna and to said first, said second computer system, said at least one first antenna being positioned in proximity to said at least one second antenna and allowing data to be exchanged via a short-range point-to-point ultra-wideband communication mode of the wireless-personal-area-network type, said structure being a portion of an airport, said at least one second antenna and said at least one second transmitter/receiver being positioned at the end of a jetway such that a door of the vehicle is located facing said end of said jetway.
An immunoconjugate for use in treating a patient with a disease associated with target cells expressing CD138, the immunoconjugate comprising: at least one targeting antibody targeting CD138 expressing cells, and at least one effector molecule, wherein said targeting antibody is functionally attached to said effector molecule to form said immunoconjugate, wherein the targeting antibody comprises a light chain variable region comprising amino acid residues 24-34, 50-56 and 89-97 of SEQ ID NO: 2, and a heavy chain variable region comprising amino acid residues 31-35, 51-68 and 99-111 of SEQ ID NO: 1, wherein at least a part of the targeting antibody confers IgG4 isotype properties, wherein said at least one effector molecule is at least one maytansinoid, wherein said disease is relapsed or refractory multiple myeloma. at least one targeting antibody targeting CD138 expressing cells, and at least one effector molecule,
A tuft carrier loading apparatus for loading individual tufts into tuft retention sites spaced along an elongate tuft carrier, the apparatus including: an elongate tuft carrier having tuft retention sites spaced therealong; a guide for guiding longitudinal movement of the tuft carrier along a path of travel; a plurality of individually and selectively operable tuft feeders spaced along the path of travel, each tuft feeder being operable when selected to feed an individual tuft to a tuft retention site of the tuft carrier; a driver drivingly connected to the tuft carrier for moving the tuft carrier along the path of travel, the driver being operable to intermittently move the tuft carrier through a series of successive positions whereat predefined tuft retention sites are moved temporarily into registry with each tuft feeder; a controller for controlling selection of the tuft feeders, the controller being operable to actuate selected tuft feeders to feed tufts to those tuft retention sites in registry therewith whilst the carrier is located at each successive position; and a detector associated with each tuft retention site to detect the presence of a tuft, characterised in that the driver, on detection of an absent tuft in an absent tuft retention site following actuation of one or more selected tuft feeders resulting in failure to feed a tuft to the absent tuft retention site, is operable to move the tuft carrier into a position whereat the absent tuft retention site is moved temporarily back into registry with the or one selected tuft feeder and the controller re-actuates the selected tuft feeder to feed a tuft to the absent tuft retention site. an elongate tuft carrier having tuft retention sites spaced therealong; a guide for guiding longitudinal movement of the tuft carrier along a path of travel; a plurality of individually and selectively operable tuft feeders spaced along the path of travel, each tuft feeder being operable when selected to feed an individual tuft to a tuft retention site of the tuft carrier; a driver drivingly connected to the tuft carrier for moving the tuft carrier along the path of travel, the driver being operable to intermittently move the tuft carrier through a series of successive positions whereat predefined tuft retention sites are moved temporarily into registry with each tuft feeder; a controller for controlling selection of the tuft feeders, the controller being operable to actuate selected tuft feeders to feed tufts to those tuft retention sites in registry therewith whilst the carrier is located at each successive position; and a detector associated with each tuft retention site to detect the presence of a tuft, characterised in that the driver, on detection of an absent tuft in an absent tuft retention site following actuation of one or more selected tuft feeders resulting in failure to feed a tuft to the absent tuft retention site, is operable to move the tuft carrier into a position whereat the absent tuft retention site is moved temporarily back into registry with the or one selected tuft feeder and the controller re-actuates the selected tuft feeder to feed a tuft to the absent tuft retention site.
A satellite radiowave receiving device, comprising: a receiver receiving radiowaves from a positioning satellite and a processor performing a positioning operation based on the radiowaves received by the receiver to obtain a current position, characterized in that: the processor calculates a first error range related to a positioning accuracy and a second error range related to a deviation of the current position and a predicted position, the positioning accuracy being obtained by combining a received state of radiowaves received from each of a plurality of positioning satellites and a relative position of the plurality of positioning satellites relative to the current positon, the predicted position being calculated in accordance with a travelling state of the satellite radiowave receiving device; the processor calculates an error range of the current position based on the first error range and the second error range; and the processor calculates the first error range by weighting a variance in the relative position of each of the plurality of positioning satellites relative to the current position using a ranging accuracy of the respective positioning satellites in accordance with strength of radiowaves received from the respective positioning satellites.
A method of sensing an interaction with an electronic device comprising a camera, the method comprising: receiving image data representative of one or more images captured by the camera; processing the image data representative of the one or more images to determine a type for a hand gesture and a location of the hand gesture in the one or more images; processing the image data representative of the one or more images to determine a plurality of face landmark locations in the image; comparing the location of the hand gesture to each face landmark location of the plurality of face landmark locations; identifying, based on the comparing, a selected face landmark, the selected face landmark having a selected face landmark location, among the plurality of face landmark locations, having a greatest proximity to the location of the hand gesture; identifying, based on the comparing and the type for the hand gesture, an action, wherein the identifying the action is further based on the selected face landmark; and providing an indication of the action, wherein the action comprises adding an augmented reality element to the image and the method further comprises selecting, based on the selected face landmark, the augmented reality element to add to the image, wherein the processing the image comprises adding the augmented reality element spatially associated with the selected face landmark to the processed image. receiving image data representative of one or more images captured by the camera; processing the image data representative of the one or more images to determine a type for a hand gesture and a location of the hand gesture in the one or more images; processing the image data representative of the one or more images to determine a plurality of face landmark locations in the image; comparing the location of the hand gesture to each face landmark location of the plurality of face landmark locations; identifying, based on the comparing, a selected face landmark, the selected face landmark having a selected face landmark location, among the plurality of face landmark locations, having a greatest proximity to the location of the hand gesture; identifying, based on the comparing and the type for the hand gesture, an action, wherein the identifying the action is further based on the selected face landmark; and providing an indication of the action, wherein the action comprises adding an augmented reality element to the image and the method further comprises selecting, based on the selected face landmark, the augmented reality element to add to the image, wherein the processing the image comprises adding the augmented reality element spatially associated with the selected face landmark to the processed image.
A light emitting device package comprising: a body comprising a recess; a first electrode and a second electrode disposed on the body; a light emitting device disposed on the first electrode; and a molding part disposed on the light emitting device and on top surfaces of the first and second electrodes, wherein a portion of the body is disposed under the first and second electrodes (211,213), and wherein at least the molding part and said portion of the body comprises benzotriazol. a body comprising a recess; a first electrode and a second electrode disposed on the body; a light emitting device disposed on the first electrode; and a molding part disposed on the light emitting device and on top surfaces of the first and second electrodes, wherein a portion of the body is disposed under the first and second electrodes (211,213), and wherein at least the molding part and said portion of the body comprises benzotriazol.
A method performed by a wireless device, the method comprising: receiving, from a network node, information indicating whether or not a medium access control, MAC, service data unit, SDU, for a signaling radio bearer, SRB, or data radio bearer, DRB, is to be received by the wireless device in the same MAC protocol data unit, PDU, as a MAC PDU carrying a random access success response message, wherein the random access success response message indicates both a random access channel and an uplink shared channel payload were decoded successfully.
A cosmetic ink composition for inkjet printing applications comprising: a. from 1 to 30 active wt % titanium dioxide, preferably from 10 to 18 active wt % titanium dioxide, having a Particle Size Distribution D50 of 100 nm to 2,000 nm, preferably having a Particle Size Distribution D50 of from 250 nm to 650 nm; as measured using a laser scattering particle size distribution analyzer as described in the description; b. a polymeric dispersant having a weight average molecular weight of less than 20,000 daltons, preferably having a weight average molecular weight of from 1,000 to 10,000 daltons; as measured by High Performance Size Exclusion Chromoatography per ASTM method D5296-11; and c. a polymeric rheology modifier selected from the group consisting of alkali swellable emulsion polymers, hydrophobically modified alkali swellable emulsion polymers, and combinations thereof, preferably greater than 0.30 active wt % of the polymeric rheology modifier; wherein the cosmetic ink composition has from 0.1 to 20 mm of separation after 11 days of static storage at 40°C, 1 atm, 60% relative humidity, in an 8-dram glass vial; wherein the separation is syneresis and wherein the cosmetic ink composition has a tan(delta) from 0.2 to 0.8 wherein the tan(delta) is the ratio of the loss modulus (G") to the storage modulus (G') wherein the storage modulus (G') and the loss modulus (G") are measured according to the Oscillatory Strain Sweep Method as disclosed in the appended description. a. from 1 to 30 active wt % titanium dioxide, preferably from 10 to 18 active wt % titanium dioxide, having a Particle Size Distribution D50 of 100 nm to 2,000 nm, preferably having a Particle Size Distribution D50 of from 250 nm to 650 nm; as measured using a laser scattering particle size distribution analyzer as described in the description; b. a polymeric dispersant having a weight average molecular weight of less than 20,000 daltons, preferably having a weight average molecular weight of from 1,000 to 10,000 daltons; as measured by High Performance Size Exclusion Chromoatography per ASTM method D5296-11; and c. a polymeric rheology modifier selected from the group consisting of alkali swellable emulsion polymers, hydrophobically modified alkali swellable emulsion polymers, and combinations thereof, preferably greater than 0.30 active wt % of the polymeric rheology modifier;
An aircraft control link (600, 700, 800) with an impact-resistant structure having a redundant load path for carrying loads of a flight control system, comprising: a first elongated structure (602, 702, 802) having a first end and a second end; a second elongated structure (601, 701, 801) having a first end and a second end, the second elongated structure (601, 701, 801) having a tubular shape with an inner wall, wherein the first elongated structure (602, 702, 802) is disposed entirely within the second elongated structure (601, 701, 801) and spaced apart from the inner wall; a first end connector (603, 703, 803) attached both to the first end of the first elongated structure (602, 702, 802) and to the first end of the second elongated structure (601, 701, 801); and a second end connector (603, 703, 803) attached both to the second end of the first elongated structure (602, 702, 802) and to the second end of the second elongated structure (601, 701, 801), characterized in that any load forces applied to the aircraft control link (600, 700, 800) are carried by both the first elongated structure (602, 702, 802) and the second elongated structure (601, 701, 801). a first elongated structure (602, 702, 802) having a first end and a second end; a second elongated structure (601, 701, 801) having a first end and a second end, the second elongated structure (601, 701, 801) having a tubular shape with an inner wall, wherein the first elongated structure (602, 702, 802) is disposed entirely within the second elongated structure (601, 701, 801) and spaced apart from the inner wall; a first end connector (603, 703, 803) attached both to the first end of the first elongated structure (602, 702, 802) and to the first end of the second elongated structure (601, 701, 801); and a second end connector (603, 703, 803) attached both to the second end of the first elongated structure (602, 702, 802) and to the second end of the second elongated structure (601, 701, 801), characterized in that any load forces applied to the aircraft control link (600, 700, 800) are carried by both the first elongated structure (602, 702, 802) and the second elongated structure (601, 701, 801).
Timepiece movement comprising an oscillator which can rotate about a first axis, a striker which can rotate about a second axis for communicating mechanical energy impulses to the oscillator, a source of energy and a transmission device connecting the source of energy to the striker, the transmission device comprising a constant force device for periodically storing an amount of energy to be provided to the striker, the constant force device comprising a bistable resilient member, the striker or the oscillator comprising a fork (16, 17) arranged to cooperate with a pin of the oscillator or of the striker respectively, the fork comprising first and second horns (16, 17), the fork and the pin each being made from one of the following materials: steel, aluminium oxide, silicon, metallic glass, characterised in that said amount of energy, the geometry of the striker and the moments of inertia of the striker and of the oscillator are selected such that upon each impulse communicated to the oscillator by the striker the following relationship is substantially met: ω 1 i = 2 ⋅ I 2 ⋅ d 1 ⋅ d 2 I 2 ⋅ d 1 2 − I 1 ⋅ d 2 2 ⋅ ω 2 i where I 1 is the moment of inertia of the striker with respect to the second axis, I 2 is the moment of inertia of the oscillator with respect to the first axis, ω 1i is the angular speed of the striker just before the impulse which it provides to the oscillator, ω 2i is the angular speed of the oscillator just before said impulse, d 1 is the lever arm of the striker and d 2 is the lever arm of the oscillator, and in that the spacing between the first and second horns (16, 17), measured between the respective points of the first and second horns (16, 17) which strike or are struck by the pin during said impulses, is greater than 1.5 times, preferably greater than 1.6 times, preferably greater than 1.7 times, preferably greater than 1.8 times, preferably greater than 1.9 times, more preferably greater than 2 times, the diameter of the pin.
Human interface operating device for an underground mining machine, comprising a rotatably and axially actuatable control element for controlling functions of the underground mining machine, further comprising a base body configured to be secured to a housing of a control cabinet of the underground mining machine, wherein the control element is rotatably and translationally supported in the base body, wherein the control element, at an inside-end section, is provided with a widened portion which, in a radial direction of the control element, protrudes beyond an engagement portion of a shaft, wherein the control element, at an outside-end section, is provided with a knob releasably mounted to the shaft, wherein a spring element is interposed between the knob and an outer surface of the base body, characterized in that the knob 50 is received in its entirety within a recess provided at an outer end of the operating device. further comprising a base body configured to be secured to a housing of a control cabinet of the underground mining machine, wherein the control element is rotatably and translationally supported in the base body, wherein the control element, at an inside-end section, is provided with a widened portion which, in a radial direction of the control element, protrudes beyond an engagement portion of a shaft, wherein the control element, at an outside-end section, is provided with a knob releasably mounted to the shaft, wherein a spring element is interposed between the knob and an outer surface of the base body, characterized in that the knob 50 is received in its entirety within a recess provided at an outer end of the operating device.