mhurhangee/ep-ind-claims huggingface dataset:
A compound of formula: wherein X is -N(R a)- or -O-; L 1 is C 1 -C 10 alkylene, C 1 -C 10 heteroalkylene, -C -, or deleted; L 2 is C 1 -C 10 alkylene, C 1 -C 10 heteroalkylene, or deleted; L 3 is aryl, or C 3 -C 20 cycloalkyl; each of R 1, and R 2, independently, is H, C 1 -C 10 alkyl, C 3 -C 20 cycloalkyl, C 3 -C 20 heterocycloalkyl, aryl, heteroaryl, halo, CN, OR c, COOR c, OC R c, C R c, C NR c R d, or NR c R d; R 3 is C 3 -C 20 heterocycloalkyl optionally substituted with C 1 -C 10 alkyl, C 3 -C 20 cycloalkyl, C 3 -C 20 heterocycloalkyl, aryl, OR', C R', COOR', C N(R'R"), SO 2 R', C N(R'R"), OSO 3 R', or PO(OR') 2, in which each of R' and R", independently, is H, C 1 -C 10 alkyl, C 3 -C 20 cycloalkyl, C 3 -C 20 heterocycloalkyl, aryl, or heteroaryl; R 4 is H; and R 5 is C 3 -C 20 cycloalkyl or C 1 -C 10 alkyl substituted with C 3 -C 20 cycloalkyl, C 3 -C 20 heterocycloalkyl, or N(R e R f); in which each of R a, R b, R c, R d, R e, and R f, independently, is H, C 1 -C 10 alkyl, C 3 -C 20 cycloalkyl, C 3 -C 20 heterocycloalkyl, aryl, heteroaryl, or -C R; R being H, C 1 -C 10 alkyl, C 3 -C 20 cycloalkyl, C 3 -C 20 heterocycloalkyl, aryl, or heteroaryl; or a salt thereof. X is -N(R a)- or -O-; L 1 is C 1 -C 10 alkylene, C 1 -C 10 heteroalkylene, -C -, or deleted; L 2 is C 1 -C 10 alkylene, C 1 -C 10 heteroalkylene, or deleted; L 3 is aryl, or C 3 -C 20 cycloalkyl; each of R 1, and R 2, independently, is H, C 1 -C 10 alkyl, C 3 -C 20 cycloalkyl, C 3 -C 20 heterocycloalkyl, aryl, heteroaryl, halo, CN, OR c, COOR c, OC R c, C R c, C NR c R d, or NR c R d; R 3 is C 3 -C 20 heterocycloalkyl optionally substituted with C 1 -C 10 alkyl, C 3 -C 20 cycloalkyl, C 3 -C 20 heterocycloalkyl, aryl, OR', C R', COOR', C N(R'R"), SO 2 R', C N(R'R"), OSO 3 R', or PO(OR') 2, in which each of R' and R", independently, is H, C 1 -C 10 alkyl, C 3 -C 20 cycloalkyl, C 3 -C 20 heterocycloalkyl, aryl, or heteroaryl; R 4 is H; and R 5 is C 3 -C 20 cycloalkyl or C 1 -C 10 alkyl substituted with C 3 -C 20 cycloalkyl, C 3 -C 20 heterocycloalkyl, or N(R e R f);
A tractor, comprising: an opening/closing support part for an engine bonnet which covers an engine, wherein the opening/closing support part comprises a supporting part of a vehicle body side and an attaching part of an engine bonnet side, and the opening/closing support part is disposed on an upper part of a rear side of the engine bonnet, characterized in that the supporting part which protrudes toward a rear side portion of the engine bonnet is provided with left-and-right pivot shafts (11 L, 11 R), the attaching parts are rotatably attached to the left-and-right pivot shafts (11L, 11R) respectively so that a front side of the engine bonnet may be opened/closed, and a notch part is formed on the rear side portion of the engine bonnet so that the supporting part of the vehicle body side may be avoided. an opening/closing support part for an engine bonnet which covers an engine, wherein the opening/closing support part comprises a supporting part of a vehicle body side and an attaching part of an engine bonnet side, and the opening/closing support part is disposed on an upper part of a rear side of the engine bonnet, characterized in that the supporting part which protrudes toward a rear side portion of the engine bonnet is provided with left-and-right pivot shafts (11 L, 11 R), the attaching parts are rotatably attached to the left-and-right pivot shafts (11L, 11R) respectively so that a front side of the engine bonnet may be opened/closed, and a notch part is formed on the rear side portion of the engine bonnet so that the supporting part of the vehicle body side may be avoided.
An isolated antibody or antigen binding portion thereof, characterized in that the antibody or antigen binding portion thereof specifically binds to sclerostin polypeptide and comprises: (a) a heavy chain variable region CDR1 comprising an amino acid sequence consisting of SEQ ID NO:4; (b) a heavy chain variable region CDR2 comprising an amino acid sequence consisting of SEQ ID NO:15; (c) a heavy chain variable region CDR3 comprising an amino acid sequence consisting of SEQ ID NO:26; (d) a light chain variable region CDR1 comprising an amino acid sequence consisting of SEQ ID NO:37; (e) a light chain variable region CDR2 comprising an amino acid sequence consisting of SEQ ID NO:48; and (f) a light chain variable region CDR3 comprising an amino acid sequence consisting of SEQ ID NO:59. (a) a heavy chain variable region CDR1 comprising an amino acid sequence consisting of SEQ ID NO:4; (b) a heavy chain variable region CDR2 comprising an amino acid sequence consisting of SEQ ID NO:15; (c) a heavy chain variable region CDR3 comprising an amino acid sequence consisting of SEQ ID NO:26; (d) a light chain variable region CDR1 comprising an amino acid sequence consisting of SEQ ID NO:37; (e) a light chain variable region CDR2 comprising an amino acid sequence consisting of SEQ ID NO:48; and (f) a light chain variable region CDR3 comprising an amino acid sequence consisting of SEQ ID NO:59.
A method for signalling, to a terminal, the substitution of content broadcast via a broadcast network to which said terminal is connected by substitution content targeted at least for said terminal, characterised in that it comprises, implemented in a broadcast system: - obtaining at least one packet of substitution information in SCTE 35 format comprising one piece of PTS, for "Presentation TimeStamp", temporal information indicative of an instant of execution by said terminal of at least one action for the substitution of the broadcast content by the substitution content, said one piece of temporal information corresponding to a date of restitution of an image of said broadcast content with reference to a reference clock embedded in said broadcast content; - generating at least one event notification message "StreamEvent" in DSM-CC format comprising at least one piece of temporal information among the temporal information received via said at least one packet of substitution information; and - inserting, into a data stream conveying said content broadcast within said broadcast network, said at least one event notification message at a temporal location prior to said at least one piece of temporal information in a chronological order of restitution of the images of said broadcast content. - obtaining at least one packet of substitution information in SCTE 35 format comprising one piece of PTS, for "Presentation TimeStamp", temporal information indicative of an instant of execution by said terminal of at least one action for the substitution of the broadcast content by the substitution content, said one piece of temporal information corresponding to a date of restitution of an image of said broadcast content with reference to a reference clock embedded in said broadcast content; - generating at least one event notification message "StreamEvent" in DSM-CC format comprising at least one piece of temporal information among the temporal information received via said at least one packet of substitution information; and - inserting, into a data stream conveying said content broadcast within said broadcast network, said at least one event notification message at a temporal location prior to said at least one piece of temporal information in a chronological order of restitution of the images of said broadcast content.
A body fluid composition being a blood serum aerosol for use in the treatment or for alleviating the symptoms of a disease or disorder by the inhalation of said blood serum aerosol to the respiratory system; wherein said blood serum aerosol comprises a therapeutically effective amount of one or more miRNA molecule(s), said miRNA being upregulated in peripheral blood upon activation of said peripheral blood by a method comprising the steps of incubating said blood collected from a mammal in contact with an increased surface area; and collecting said activated serum produced, wherein said disease or disorder is selected from respiratory fibrosis, a respiratory hypersensitivity disorder, a cancer, such as lung cancer, non-small cell lung cancer (NSCLC), pulmonary hypertension, chronic obstructive lung disease (COLD), also known as Chronic Obstructive Pulmonary Disease (COPD), Recurrent Airway Obstruction also known as Heaves, Inflammatory Airway Disease, Exercise-Induced Pulmonary Haemorrhage (EIPH), cystic fibrosis, and asthma.
Hydraulic accumulator, in particular low-pressure accumulator, with an accumulator housing and a separating element in the form of an accumulator bladder arranged therein, which separates two media chambers (3, 5) from each other, wherein the accumulator housing is formed of at least two shells (8, 10), of which at least one has a central hole via which the accumulator bladder, in one of the shells (8, 10), can be filled with working gas, wherein the shells (8, 10) are welded together at their end regions directed towards each other, characterised in that the shells (8, 10) are formed from deep-drawn metallic material, and in that the accumulator bladder at its opening is held in tight contact on the margin of the hole which, while forming a filling connection of correspondingly small dimensions, prevents the accumulator bladder from being installed or removed.
A door system with a door drive having at least one connecting element for connection to a leaf element and/or at least one leaf element to which the door drive is operatively connected in a driving manner, wherein the at least one leaf element of the door system can be moved with the door drive, wherein the door drive has a motor unit with a housing, in which a stator is accommodated in a stationary manner and wherein a rotor is arranged in the housing so as to be rotatably movable and has an output shaft, wherein the output shaft can be brought into operative connection with the leaf element in a driving manner, wherein the motor unit has the basic shape of a cuboid, which is formed at least by means of two housing halves (15, 16) connected to one another, and wherein the stator and the rotor are accommodated on the inside between the housing halves (15, 16), characterised in that the housing halves (15, 16) are configured in a shell-like manner and rest directly against one another such that a circumferential, approximately rectangular edge of the respective housing half is joined together, and wherein the cuboid has a longitudinal edge, a lateral edge and a vertical edge, wherein the longitudinal edge is larger than the lateral edge and/or wherein the lateral edge is larger than the vertical edge.
System for processing video and/or audio signals, wherein the system comprises a control unit and two or more processing units (401, 403, 405), wherein the control unit and the processing units (401, 403, 405) are communicatively connected by data links for exchanging digital data in a packetized format, wherein the data links provide for latencies which are constant, wherein the packetized data represent video and/or audio signals and command signals communicated between the control unit and the two or more processing units, wherein each processing unit is associated with a command scheduler (501, 503, 504) forwarding command signals (A, B, C) to a delay stage (CMD DEL) of the associated processing unit, wherein the delay stages in different processing units enable synchronized command execution between multiple processing units (401, 403, 405) by compensating command signal latencies and latencies introduced by processing times.
A rotating device which is a mechanical component manufactured by a method comprising: a step of preparing a martensitic stainless steel containing, by mass%, C: 0.20% to 0.40%, N: 0.1% or less, Mo: 3% or less, and Cr: 12.0% to 16.0%, such that 0.3%≤C+N≤0.4% and a PI value =Cr+3.3Mo+16N is 18 or more, with the remainder of Fe and unavoidable impurities; a step of quenching from a temperature of 1,030 to 1,140°C; a step of a subzero treatment; and a step of tempering, so as to obtain a prior austenite crystal grain size of a surface layer extending up to 0.2 mm from the surface of 30 μm to 100 μm and a surface hardness of 58 HRc to 62 HRc.
A method in a user equipment for handling a scheduling request, SR, the user equipment is served by a base station in a cellular communications network, the method comprising, receiving (201, 501) from the base station, a first message comprising a first assignment of SR resources, which first message is received using a first protocol, wherein the first assignment of SR resources is semi-static, the method further comprising: receiving (205, 503) from the base station, a second message comprising a second assignment of SR resources, said SR resources according to said second assignment being additional resources to the SR resources assigned according to said first assignment, which second message is received using a second protocol, and wherein the second protocol is associated with a layer that is lower than a layer associated with the first protocol applying (202, 206, 504) the SR resources according to the first assignment and the SR resources according to the second assignment at the same time or separately. receiving (205, 503) from the base station, a second message comprising a second assignment of SR resources, said SR resources according to said second assignment being additional resources to the SR resources assigned according to said first assignment, which second message is received using a second protocol, and wherein the second protocol is associated with a layer that is lower than a layer associated with the first protocol applying (202, 206, 504) the SR resources according to the first assignment and the SR resources according to the second assignment at the same time or separately.
Process box for a coating installation, comprising - a cuboidal channel housing with two mutually opposite vertical face sides, two vertical narrow sides perpendicular thereto, and two horizontal broad sides (14; 141, 142) perpendicular to the face sides and the narrow sides, - two mutually opposite openings (18, 22) in the upper and the lower broad side (141, 142) for through-passage of an axially movable coating lance, and - at least one air inlet and one air outlet in the sides perpendicular to the broad sides, which are connectable or connected to a blower device, characterized in that the air inlet and the air outlet take up the entire area of the face sides. - a cuboidal channel housing with two mutually opposite vertical face sides, two vertical narrow sides perpendicular thereto, and two horizontal broad sides (14; 141, 142) perpendicular to the face sides and the narrow sides, - two mutually opposite openings (18, 22) in the upper and the lower broad side (141, 142) for through-passage of an axially movable coating lance, and - at least one air inlet and one air outlet in the sides perpendicular to the broad sides, which are connectable or connected to a blower device,
Method for coating a cold-formed multi-cone anchoring element for chemical fastening technology, comprising the following steps: i) providing a cold-formed multi-cone anchoring element, ii) galvanizing the cold-formed multi-cone anchoring element, iii) applying a protective coating, iv) applying a primer, and v) applying a top coating. i) providing a cold-formed multi-cone anchoring element, ii) galvanizing the cold-formed multi-cone anchoring element, iii) applying a protective coating, iv) applying a primer, and v) applying a top coating.
A radar system comprising: a compression component configured to compress blocks of range values, the range values comprising samples output by a range FFT, and to generate compressed blocks of range values; and a radar data memory configured to store compressed blocks of range values generated by the compression component; wherein the compression component is configured to provide at least two types of compression that comprise block floating point, BFP, compression and order k exponential Golomb, EG, compression; and wherein the compression component is configured to select a type of compression for a block of range values from the at least two types of compression based on a quantization error of each type of compression, and is configured to use the selected one type of compression to compress the block of range values. a compression component configured to compress blocks of range values, the range values comprising samples output by a range FFT, and to generate compressed blocks of range values; and a radar data memory configured to store compressed blocks of range values generated by the compression component; wherein the compression component is configured to provide at least two types of compression that comprise block floating point, BFP, compression and order k exponential Golomb, EG, compression; and wherein the compression component is configured to select a type of compression for a block of range values from the at least two types of compression based on a quantization error of each type of compression, and is configured to use the selected one type of compression to compress the block of range values.
A method of processing an active ingredient or ingredients for inhalation, the method comprising submitting a pharmaceutically active ingredient or ingredients alone to compression and shearing forces, wherein the active ingredient or ingredients are micronised before processing, the active ingredient or ingredients comprise glycopyrrolate or a pharmaceutically acceptable salt thereof, and the compressive and shearing forces are provided by compressive milling within a vessel, in which the ingredient or ingredients are subjected to a centrifugal force pressing them against the vessel inner wall, compressing the ingredient or ingredients between the fixed clearance of the drum wall and a curved inner element with high relative speed between drum and element, the inner wall and curved element together forming a gap or nip in which particles of the ingredient or ingredients are pressed together.
An electrical enclosure comprising: at least one circuit breaker compartment; a cover mounted to the electrical enclosure, the cover including an opening receptive of at least one circuit breaker; and a gasket extended about at least a portion of the opening, the gasket including an inner seal assembly and an outer seal assembly, the outer seal assembly positioned to engage the at least one circuit breaker when the cover is in a closed position with respect to the at least one circuit breaker, characterized in that the inner seal assembly is movable between a non-deployed configuration and a deployed configuration; wherein the inner seal assembly in the non-deployed configuration is spaced from the at least one circuit breaker in the closed position of the cover, and the inner seal assembly is responsive to a pressure wave in the at least one circuit breaker compartment to move from the non-deployed configuration to the deployed configuration to engage the at least one circuit breaker and substantially prevent out gassing through the opening in the cover. at least one circuit breaker compartment; a cover mounted to the electrical enclosure, the cover including an opening receptive of at least one circuit breaker; and a gasket extended about at least a portion of the opening, the gasket including an inner seal assembly and an outer seal assembly, the outer seal assembly positioned to engage the at least one circuit breaker when the cover is in a closed position with respect to the at least one circuit breaker, characterized in that the inner seal assembly is movable between a non-deployed configuration and a deployed configuration; wherein the inner seal assembly in the non-deployed configuration is spaced from the at least one circuit breaker in the closed position of the cover, and the inner seal assembly is responsive to a pressure wave in the at least one circuit breaker compartment to move from the non-deployed configuration to the deployed configuration to engage the at least one circuit breaker and substantially prevent out gassing through the opening in the cover.
An external drive unit for an implantable heart assist pump comprising a motor housing, a transcutaneous drive shaft and a motor for driving the heart assist pump, wherein the motor is connectable to the heart assist pump via the drive shaft and wherein the motor is arranged inside the motor housing, further comprising a catheter surrounding the drive shaft and a purge line for injecting a purge medium into a lumen of the catheter or into a space between the catheter and the drive shaft, wherein the purge line is in thermal contact (54, 55) with an outer surface of the motor housing, characterized in that the purge line is configured to guide the purge medium such that it first comes into thermal contact with the outer surface of the motor housing and is afterwards injected into the lumen of the catheter or into the space between the catheter and the drive shaft. a motor housing, a transcutaneous drive shaft and a motor for driving the heart assist pump, wherein the motor is connectable to the heart assist pump via the drive shaft and wherein the motor is arranged inside the motor housing, further comprising a catheter surrounding the drive shaft and a purge line for injecting a purge medium into a lumen of the catheter or into a space between the catheter and the drive shaft, wherein the purge line is in thermal contact (54, 55) with an outer surface of the motor housing, characterized in that the purge line is configured to guide the purge medium such that it first comes into thermal contact with the outer surface of the motor housing and is afterwards injected into the lumen of the catheter or into the space between the catheter and the drive shaft.
Gas drive for a firearm having a gun barrel arranged on a breechblock housing and a gas discharge device arranged on the gun barrel and having a pressure chamber connected to a barrel borehole in the gun barrel via a gas removal channel (14, 15) and which at a rear side seen in firing direction is defined by a breechblock actuating element which is movable by means of the pressure in the pressure chamber in the direction of the breechblock housing or guiding the pressure in the pressure chamber to the breechblock housing and at its front side seen in firing direction by a front part, characterised in that the gun barrel is movable axially relative to the front part of the gas discharge device supported on the breechblock housing via a support element.