A refrigerant vapor compression system comprising: a compression device having at least a first compression stage and a second compression stage arranged in series refrigerant flow relationship; a first refrigerant heat rejection heat exchanger disposed downstream with respect to refrigerant flow of the second compression stage for passing the refrigerant in heat exchange relationship with a flow of a first secondary fluid; a first refrigerant intercooler disposed intermediate the first compression stage and the second compression stage for passing the refrigerant passing from the first compression stage to the second compression stage in heat exchange relationship with the flow of the first secondary fluid; an economizer circuit including a vapor line in fluid communication with a suction inlet to the second compression stage; a second refrigerant heat rejection heat exchanger disposed intermediate with respect to refrigerant flow of the second compression stage and the first refrigerant heat rejection heat exchanger; and a second refrigerant intercooler disposed intermediate the first compression stage and the second compression stage and in heat exchange relationship with a second secondary fluid, characterized in that: the first refrigerant intercooler is disposed downstream of the first refrigerant heat rejection heat exchanger with respect to the flow of the first secondary fluid; and the second refrigerant intercooler is disposed downstream with respect to refrigerant flow of the vapor line for passing the refrigerant from the first compression stage to the second compression stage. a compression device having at least a first compression stage and a second compression stage arranged in series refrigerant flow relationship; a first refrigerant heat rejection heat exchanger disposed downstream with respect to refrigerant flow of the second compression stage for passing the refrigerant in heat exchange relationship with a flow of a first secondary fluid; a first refrigerant intercooler disposed intermediate the first compression stage and the second compression stage for passing the refrigerant passing from the first compression stage to the second compression stage in heat exchange relationship with the flow of the first secondary fluid; an economizer circuit including a vapor line in fluid communication with a suction inlet to the second compression stage; a second refrigerant heat rejection heat exchanger disposed intermediate with respect to refrigerant flow of the second compression stage and the first refrigerant heat rejection heat exchanger; and a second refrigerant intercooler disposed intermediate the first compression stage and the second compression stage and in heat exchange relationship with a second secondary fluid, characterized in that: the first refrigerant intercooler is disposed downstream of the first refrigerant heat rejection heat exchanger with respect to the flow of the first secondary fluid; and the second refrigerant intercooler is disposed downstream with respect to refrigerant flow of the vapor line for passing the refrigerant from the first compression stage to the second compression stage. the first refrigerant intercooler is disposed downstream of the first refrigerant heat rejection heat exchanger with respect to the flow of the first secondary fluid; and the second refrigerant intercooler is disposed downstream with respect to refrigerant flow of the vapor line for passing the refrigerant from the first compression stage to the second compression stage.