A stent comprising: a first section and a second section (801 B), the second section aligned with the first section along a longitudinal axis of the stent, each section including: a plurality of expandable modules, each expandable module including a plurality of strut elements that join together at a plurality of apices; and a plurality of bridging modules, each bridging module including bridging elements that connect an apex of a first module with an apex of a second module, wherein the plurality of bridging modules are arranged to alternate along the longitudinal axis between clockwise bridging modules and counterclockwise bridging modules, the clockwise bridging modules including bridging elements that extend at a clockwise angle with respect to the longitudinal axis, and the counterclockwise bridging modules including bridging elements that extend at a counterclockwise angle with respect to the longitudinal axis; wherein the stent is configured to be placed in a vein such that the first section is in a first region of the vein and the second section is in a second region of the vein; wherein the first section is more radially stiff than the second section such that the first section is more resistant to physiologic compression than the second section; and further comprising a third section, the third section (801 C) adjacent to the second section and located along the longitudinal axis of the stent, wherein the stent is configured to be placed in the vein such that the third section is in a third region of the vein and wherein the third section is more radially stiff than the second section such that the third section is more resistant to physiologic compression than the second section. a first section and a second section (801 B), the second section aligned with the first section along a longitudinal axis of the stent, each section including: a plurality of expandable modules, each expandable module including a plurality of strut elements that join together at a plurality of apices; and a plurality of bridging modules, each bridging module including bridging elements that connect an apex of a first module with an apex of a second module, wherein the plurality of bridging modules are arranged to alternate along the longitudinal axis between clockwise bridging modules and counterclockwise bridging modules, the clockwise bridging modules including bridging elements that extend at a clockwise angle with respect to the longitudinal axis, and the counterclockwise bridging modules including bridging elements that extend at a counterclockwise angle with respect to the longitudinal axis; a plurality of expandable modules, each expandable module including a plurality of strut elements that join together at a plurality of apices; and a plurality of bridging modules, each bridging module including bridging elements that connect an apex of a first module with an apex of a second module, wherein the plurality of bridging modules are arranged to alternate along the longitudinal axis between clockwise bridging modules and counterclockwise bridging modules, the clockwise bridging modules including bridging elements that extend at a clockwise angle with respect to the longitudinal axis, and the counterclockwise bridging modules including bridging elements that extend at a counterclockwise angle with respect to the longitudinal axis; wherein the stent is configured to be placed in a vein such that the first section is in a first region of the vein and the second section is in a second region of the vein; wherein the first section is more radially stiff than the second section such that the first section is more resistant to physiologic compression than the second section; and further comprising a third section, the third section (801 C) adjacent to the second section and located along the longitudinal axis of the stent, wherein the stent is configured to be placed in the vein such that the third section is in a third region of the vein and wherein the third section is more radially stiff than the second section such that the third section is more resistant to physiologic compression than the second section.