mhurhangee/ep-ind-claims huggingface dataset:
A process for preparing crystalline particles of an active principal in the presence of ultrasonic irradiation that comprises contacting a solution of at least one solute in a solvent in a first flowing stream with an anti-solvent in a second flowing stream causing the mixing thereof, wherein the flow rate ratio of the anti-solvent: solvent is higher than 20:1, wherein the second flowing stream is a continuously recycling anti-solvent stream that comprises anti-solvent and may also comprise added solute in solvent; and wherein the solute comprises at least one active principal or a precursor thereof; and collecting crystals that are generated.
A method for preparing a slurry mixture in a microfluidic device, the method comprising: providing in the microfluidic device a first micropump, a second micropump fluidly coupled to the first micropump by a first microchannel comprising a microvalve, and a third micropump fluidly coupled to the second micropump by a second microchannel; each of the micropumps (MP1, MP2, MP3) comprising a chamber comprising a pneumatically deformable diaphragm changeable between a closed position for discharging pumping a fluid and an open position for receiving the fluid; opening a slurry inlet microvalve fluidly coupled to the first micropump; changing position of the first micropump from the closed position to the open position; drawing slurry into the first micropump; closing the slurry inlet microvalve; opening an extractant inlet microvalve fluidly coupled to the first micropump; opening the intermediate microvalve disposed in the first microchannel between the first and second micropumps (MP1, MP2); changing position of the second micropump from the closed position to the open position; drawing extractant into the first micropump; and mixing the slurry and extractant form a slurry-extractant mixture. providing in the microfluidic device a first micropump, a second micropump fluidly coupled to the first micropump by a first microchannel comprising a microvalve, and a third micropump fluidly coupled to the second micropump by a second microchannel; each of the micropumps (MP1, MP2, MP3) comprising a chamber comprising a pneumatically deformable diaphragm changeable between a closed position for discharging pumping a fluid and an open position for receiving the fluid; opening a slurry inlet microvalve fluidly coupled to the first micropump; changing position of the first micropump from the closed position to the open position; drawing slurry into the first micropump; closing the slurry inlet microvalve; opening an extractant inlet microvalve fluidly coupled to the first micropump; opening the intermediate microvalve disposed in the first microchannel between the first and second micropumps (MP1, MP2); changing position of the second micropump from the closed position to the open position; drawing extractant into the first micropump; and mixing the slurry and extractant form a slurry-extractant mixture.
Imidazolium compound of formula: wherein said compound is associated with an « A-» counter-ion, A being chosen from a halide, P(R 4) 6 -, B(R 4) 4 -, SCN -, (R 5 SO 2) 2 N -, R 5 OSO 3, R 5 SO 3 -, carborane, carbonate, hydrogen carbonate, alcoholate, carboxylate, amide, phosphate, SiF 6 -, SbF 6 -, I 3 -, nitrate, halide oxide, silicate, sulfate, sulfonate, cyanide, carbanions or metallate, wherein: R 4 on each occurrence is a group independently selected from among a halogen atom, C 1 -C 6 alkyl group, C 6 -C 10 aryl group, an aralkyl group; R 5 on each occurrence is a group independently selected from among C 1 -C 20 alkyl, C 1 -C 20 haloalkyl, C 6 -C 10 aryl, aralkyl. wherein said compound is associated with an « A-» counter-ion, A being chosen from a halide, P(R 4) 6 -, B(R 4) 4 -, SCN -, (R 5 SO 2) 2 N -, R 5 OSO 3, R 5 SO 3 -, carborane, carbonate, hydrogen carbonate, alcoholate, carboxylate, amide, phosphate, SiF 6 -, SbF 6 -, I 3 -, nitrate, halide oxide, silicate, sulfate, sulfonate, cyanide, carbanions or metallate, wherein: R 4 on each occurrence is a group independently selected from among a halogen atom, C 1 -C 6 alkyl group, C 6 -C 10 aryl group, an aralkyl group; R 5 on each occurrence is a group independently selected from among C 1 -C 20 alkyl, C 1 -C 20 haloalkyl, C 6 -C 10 aryl, aralkyl. R 4 on each occurrence is a group independently selected from among a halogen atom, C 1 -C 6 alkyl group, C 6 -C 10 aryl group, an aralkyl group; R 5 on each occurrence is a group independently selected from among C 1 -C 20 alkyl, C 1 -C 20 haloalkyl, C 6 -C 10 aryl, aralkyl.
Heat exchanger comprising: - several plates arranged parallel to one another so as to define a first series of passages to channel at least one refrigerant fluid and a second series of passages to channel at least one calorigenic fluid to put through heat exchange with at least said refrigerant fluid, each passage (10, 20) being defined between two successive plates and extending parallel to a longitudinal axis (z), and - at least one mixing device arranged in at least one passage of the first series, said mixing device being configured to receive a liquid phase and a gaseous phase of the refrigerant fluid and distribute a mixture of said phases (61, 62) in said at least one passage, - at least one passage of the second series adjacent to said at least one passage of the first series comprising a divided heat exchange structure, along the longitudinal axis (z), in at least one first portion and a second portion juxtaposed along the longitudinal axis (z), the second portion extending facing at least one portion of the mixing device, characterised in that the second portion is configured so as to have a heat exchange coefficient less than the heat exchange coefficient of the first portion. - several plates arranged parallel to one another so as to define a first series of passages to channel at least one refrigerant fluid and a second series of passages to channel at least one calorigenic fluid to put through heat exchange with at least said refrigerant fluid, each passage (10, 20) being defined between two successive plates and extending parallel to a longitudinal axis (z), and - at least one mixing device arranged in at least one passage of the first series, said mixing device being configured to receive a liquid phase and a gaseous phase of the refrigerant fluid and distribute a mixture of said phases (61, 62) in said at least one passage, - at least one passage of the second series adjacent to said at least one passage of the first series comprising a divided heat exchange structure, along the longitudinal axis (z), in at least one first portion and a second portion juxtaposed along the longitudinal axis (z), the second portion extending facing at least one portion of the mixing device,
An oral solid dosage form comprising a purified neutral acrylic polymer and a prophylactically or therapeutically effective amount of an opioid agonist, wherein the purified neutral acrylic polymer is obtainable by drying a dispersion comprising a neutral acrylic polymer and comprises 70 - 100 % (w/w) of neutral acrylic polymer, 0 - 10 % (w/w) of water, 0 - 5 % (w/w) of organic solvents, 0 - 2 % (w/w) of emulsifiers and 0 - 5 % (w/w) of further ingredients selected from the group consisting of polymers, poloxamers, bulking agents, release modifying agents, retardants, plasticizers, stabilizers, diluents, fillers, lubricants, binders, granulating aids, colorants, flavorants and glidants, wherein said neutral acrylic polymer is a poly(meth)acrylate which does not contain free acid groups, amino groups or quaternary ammonium groups, wherein the oral solid dosage form comprises greater than about 50% (w/w) of the purified neutral acrylic polymer, and wherein the dosage form further comprises polyethylene oxide and/or a non-ionic triblock copolymer composed of a central hydrophobic chain of polyoxypropylene flanked by two hydrophilic chains of polyoxyethylene. wherein the purified neutral acrylic polymer is obtainable by drying a dispersion comprising a neutral acrylic polymer and comprises 70 - 100 % (w/w) of neutral acrylic polymer, 0 - 10 % (w/w) of water, 0 - 5 % (w/w) of organic solvents, 0 - 2 % (w/w) of emulsifiers and 0 - 5 % (w/w) of further ingredients selected from the group consisting of polymers, poloxamers, bulking agents, release modifying agents, retardants, plasticizers, stabilizers, diluents, fillers, lubricants, binders, granulating aids, colorants, flavorants and glidants, wherein said neutral acrylic polymer is a poly(meth)acrylate which does not contain free acid groups, amino groups or quaternary ammonium groups, wherein the oral solid dosage form comprises greater than about 50% (w/w) of the purified neutral acrylic polymer, and wherein the dosage form further comprises polyethylene oxide and/or a non-ionic triblock copolymer composed of a central hydrophobic chain of polyoxypropylene flanked by two hydrophilic chains of polyoxyethylene.
A fast nuclear fission reactor comprising: a fast neutron nuclear reactor core containing an array structure having multiple device locations; a nuclear fuel assembly device inserted in a first device location of the fast neutron nuclear reactor core and containing nuclear fuel having a Doppler broadening constrained within a defined energy range; and a Doppler reactivity augmentation device inserted in a second device location of the fast neutron nuclear reactor core and formed at least in part from a scattering material having a neutron scattering cross-section having at least one resonance within the defined energy range, the scattering material being formed from an alloy having at least 10% vanadium or titanium by mass, wherein the Doppler reactivity augmentation device includes an external structural wall (804, 904); and wherein either the external structural wall is an external structural wall of a control duct formed at least in part from the scattering material and configured to allow liquid coolant to flow through the control duct; or the external structural wall encompasses a core of the scattering material that includes one or more channels configured to allow liquid coolant to flow through the Doppler reactivity augmentation device. a fast neutron nuclear reactor core containing an array structure having multiple device locations; a nuclear fuel assembly device inserted in a first device location of the fast neutron nuclear reactor core and containing nuclear fuel having a Doppler broadening constrained within a defined energy range; and a Doppler reactivity augmentation device inserted in a second device location of the fast neutron nuclear reactor core and formed at least in part from a scattering material having a neutron scattering cross-section having at least one resonance within the defined energy range, the scattering material being formed from an alloy having at least 10% vanadium or titanium by mass, wherein the Doppler reactivity augmentation device includes an external structural wall (804, 904); and wherein either the external structural wall is an external structural wall of a control duct formed at least in part from the scattering material and configured to allow liquid coolant to flow through the control duct; or the external structural wall encompasses a core of the scattering material that includes one or more channels configured to allow liquid coolant to flow through the Doppler reactivity augmentation device. the external structural wall is an external structural wall of a control duct formed at least in part from the scattering material and configured to allow liquid coolant to flow through the control duct; or the external structural wall encompasses a core of the scattering material that includes one or more channels configured to allow liquid coolant to flow through the Doppler reactivity augmentation device.
An organic electroluminescent display device, comprising: a substrate; an organic light-emitting device formed over the substrate; and an encapsulation layer formed over the organic light-emitting device and the substrate, the encapsulation layer comprising an inorganic layer and a polymer organic layer stacked with an intermediate layer formed of an organic monomer between the inorganic layer and the polymer organic layer, wherein one surface of the intermediate layer is bonded to the inorganic layer, another surface of the intermediate layer is bonded to the polymer organic layer by polymerization, and the inorganic layer is the closest layer of the encapsulation layer to the substrate. a substrate; an organic light-emitting device formed over the substrate; and an encapsulation layer formed over the organic light-emitting device and the substrate, the encapsulation layer comprising an inorganic layer and a polymer organic layer stacked with an intermediate layer formed of an organic monomer between the inorganic layer and the polymer organic layer, wherein one surface of the intermediate layer is bonded to the inorganic layer, another surface of the intermediate layer is bonded to the polymer organic layer by polymerization, and the inorganic layer is the closest layer of the encapsulation layer to the substrate.
A method for controlling a motor of a powered fastener driver, characterized in that the method comprises: load testing a battery pack of the powered fastener driver by driving a crank arm against a fixed stop (102a, 102b) coupled to a housing of the powered fastener driver; determining, by a controller, an internal resistance of the battery pack by measuring one or both of a voltage and a current of the battery pack while driving the crank arm against the fixed stop; and determining, by the controller, a type of battery pack based on the determined internal resistance. load testing a battery pack of the powered fastener driver by driving a crank arm against a fixed stop (102a, 102b) coupled to a housing of the powered fastener driver; determining, by a controller, an internal resistance of the battery pack by measuring one or both of a voltage and a current of the battery pack while driving the crank arm against the fixed stop; and determining, by the controller, a type of battery pack based on the determined internal resistance.
A method of making a water-in-oil emulsion comprising a fat phase, an aqueous phase and a powdered component; the method comprising melting a fat phase comprising a first fat having a first melting point and a second fat having a second melting point lower than the first; mixing an emulsifier with the fat phase; adding an aqueous phase to the fat phase to form an emulsion; adding a powdered component to the emulsion; and cooling, wherein the emulsion continues to be mixed after powder addition whilst cooling the emulsion to a temperature between the first and second melting points.
A support assembly for the passenger compartment of a motor vehicle, comprising at least one support device (200; 300; 400; 500) comprising support means (210; 310; 410; 510) for at least one object or accessory; also comprising a rigid landing bar having a tubular body and provided to extend transversely along and above the instrument panel of said vehicle, each at least said support device (200; 300; 400; 500) also comprising means of attachment enabling it to be removably mounted on said docking bar, characterized in that the outer face of said tubular body has an electrically ground-conducting lamella extending along said docking bar and at least one electrically conductive supply lamella (114, 115, 116, 117) extending along said docking bar away from said ground slat and capable of delivering a DC supply voltage, at least a support device (200; 500) comprising means of electrical supply comprising an electrically ground-conducting track and an electrically conductive power track provided on said means of attachment and each connected by a respective conductor (228, 227) at a corresponding terminal of a power supply connector, said ground and power tracks being further capable of coming into contact with said ground blade and with said power blade (114, 115, 116 or 117) respectively when said support device (200; 500) is mounted on said docking bar.
A multi-functional monomer represented by Formula 1: [Formula 1] X-(-Y 1 -Z-Y 2 -A) a wherein A is a functional group of Formula 2: (wherein R 1 is a C 1-4 alkyl or cycloalkyl group), Z is a functional group of Formula 3: (wherein L and L' are respectively a nitrogen atom or an oxygen atom), Y 1 and Y 2 are the same as each other or different from each other, and respectively C 1-9 alkylene, X is a functional group represented by Formula 13, and a is an integer of 2:
A mounting system for mounting a plurality of a track segments to a wall, the mounting system comprising: a bracket; a track connector, wherein the mounting system has a breakaway feature that allows the track connector to be removed from the bracket suitable to be secured to a wall upon the application of a predetermined amount of force, wherein the track connector is snap fittingly engaged with the bracket when the track connector is secured to the bracket; characterised in that the breakaway feature comprises a ledge portion which is provided on the bracket and that engages a bottom portion of the track connector and a feature that is configured to engage an upper portion of the track connector when the track connector is secured to the bracket and wherein the feature snap fittingly engages the track connector when the track connector is secured to the bracket. a bracket; a track connector,
Method for recycling powdered paint waste, characterized in that it consists in mixing the paint waste derived from the technique of coating a metal object by the spraying of powdered paint with sand recovered from the sandblasting of the metal object, prior to the said technique of coating to place the said mixture (2a-2d) in a mold (1a-1d) and heating the whole in an oven, then releasing the product from the mold after cooling, to form a finished product or a semi-worked product.
A process for preparing a non-crosslinked product comprising Xanthan mixed with aluminum chloride and/or polyaluminium chloride, the product useful for dosing into and removing impurities from a liquid, characterized in that the process comprises the steps of either: a. mixing 250ml of monoethylene glycol and 100ml of water, followed by adding 25 grams of fine Xanthan powder, which is thereafter shearmixed until completely solved, adding thinned hydrochloric acid until pH 3 is reached, mixing 50g of aluminum chloride with 650mml of water under pH 3, which is then mixed with the Xanthan / MEG / Water mixture by shearmixing, or b. mixing 250ml of monoethylene glycol and 100ml of water with 25g Xanthan, which is then pH adjusted to 3, dissolving 50g of aluminum chloride in 650 ml of polyaluminium chloride with pH 2.5, and blending said mixtures into a homogeneous mixture. a. mixing 250ml of monoethylene glycol and 100ml of water, followed by adding 25 grams of fine Xanthan powder, which is thereafter shearmixed until completely solved, adding thinned hydrochloric acid until pH 3 is reached, mixing 50g of aluminum chloride with 650mml of water under pH 3, which is then mixed with the Xanthan / MEG / Water mixture by shearmixing, or b. mixing 250ml of monoethylene glycol and 100ml of water with 25g Xanthan, which is then pH adjusted to 3, dissolving 50g of aluminum chloride in 650 ml of polyaluminium chloride with pH 2.5, and blending said mixtures into a homogeneous mixture.
A machine tool comprising: workpiece holding means to hold a workpiece; a tool rest to hold a cutting tool for cutting the workpiece; feeding means (150, 160) to feed the cutting tool toward the workpiece in a predetermined feeding direction via relative movement between the workpiece holding means and the tool rest; vibration means to relatively vibrate the workpiece holding means and the tool rest so that the cutting tool is fed in the feeding direction while reciprocally vibrating in the feeding direction; and rotating means to relatively rotate the workpiece and the cutting tool, the machine tool being capable of cutting the workpiece via the relative rotation between the workpiece and the cutting tool and via the feeding of the cutting tool toward the workpiece with the reciprocal vibration in the feeding direction, wherein the machine tool comprises amplitude control means to control an amplitude of the reciprocal vibration by the vibration means, the machine tool characterised in that the amplitude control means is configured to reduce the amplitude of the reciprocal vibration by the vibration means while the cutting tool is fed in the feeding direction when the cutting tool reaches a predetermined coordinate position on the workpiece specified in a particular move instruction to move the cutting tool in the feeding direction. workpiece holding means to hold a workpiece; a tool rest to hold a cutting tool for cutting the workpiece; feeding means (150, 160) to feed the cutting tool toward the workpiece in a predetermined feeding direction via relative movement between the workpiece holding means and the tool rest; vibration means to relatively vibrate the workpiece holding means and the tool rest so that the cutting tool is fed in the feeding direction while reciprocally vibrating in the feeding direction; and rotating means to relatively rotate the workpiece and the cutting tool, the machine tool being capable of cutting the workpiece via the relative rotation between the workpiece and the cutting tool and via the feeding of the cutting tool toward the workpiece with the reciprocal vibration in the feeding direction, wherein the machine tool comprises amplitude control means to control an amplitude of the reciprocal vibration by the vibration means, the machine tool characterised in that the amplitude control means is configured to reduce the amplitude of the reciprocal vibration by the vibration means while the cutting tool is fed in the feeding direction when the cutting tool reaches a predetermined coordinate position on the workpiece specified in a particular move instruction to move the cutting tool in the feeding direction.
A PD-1 agonist for use in a prophylactic or therapeutic method for an autoimmune disease, wherein (a) the PD-1 agonist is administered 4 to 6 times, wherein the period of administration is 3 to 11 days from the first administration, and wherein the frequency of administration per day is once; (b) a total dose of the PD-1 agonist is 192 μg/kg to 1,250 μg/kg; and (c) the effect in the prophylactic or therapeutic method is sustained for at least 3 months after the last administration, wherein the PD-1 agonist is a PD-1-CD3 bispecific hybrid antibody composed of a heavy chain/light chain complex derived from an anti-PD-1 antibody, and a heavy chain/light chain complex derived from an anti-CD-3 antibody; and wherein the autoimmune disease is any one of type I diabetes mellitus, psoriasis, myasthenia gravis, idiopathic thrombocytopenia purpura, systemic lupus erythematosus, multiple sclerosis, polymyositis, dermatomyositis, rheumatoid arthritis, Sjogren syndrome, and inflammatory bowel disease. (a) the PD-1 agonist is administered 4 to 6 times, wherein the period of administration is 3 to 11 days from the first administration, and wherein the frequency of administration per day is once; (b) a total dose of the PD-1 agonist is 192 μg/kg to 1,250 μg/kg; and (c) the effect in the prophylactic or therapeutic method is sustained for at least 3 months after the last administration, wherein the PD-1 agonist is a PD-1-CD3 bispecific hybrid antibody composed of a heavy chain/light chain complex derived from an anti-PD-1 antibody, and a heavy chain/light chain complex derived from an anti-CD-3 antibody; and wherein the autoimmune disease is any one of type I diabetes mellitus, psoriasis, myasthenia gravis, idiopathic thrombocytopenia purpura, systemic lupus erythematosus, multiple sclerosis, polymyositis, dermatomyositis, rheumatoid arthritis, Sjogren syndrome, and inflammatory bowel disease.