Pipe end protector for protecting pipe threads provided on a pipe end of a pipe component for exploration and production of a hydrocarbon well, said pipe end protector comprising; - a main body having a longitudinal axis, at least one support portion having an at least partly radially extending annular seal support surface, and a tubular portion provided with protector threads configured to cooperate with the pipe threads of the pipe end, and - an annular flexible lip seal provided on the seal support surface, wherein; -- the main body is made from a first polymeric material having a first elastic modulus, -- the lip seal is made from a second polymeric material having a second elastic modulus which is lower than the first elastic modulus, and -- the lip seal comprises an annular lip base portion which extends radially along at least part of the seal support surface and is attached to the seal support surface by over moulding, -- the lip seal comprises an annular lip which extends from a foot of the lip being attached to the lip base portion to a free rim of the lip being axially spaced from the lip base portion, -- the foot and the free rim are radially offset, and characterised in that -- the lip seal is an axial lip seal, -- the axial lip seal comprises an annular support base portion which extends radially along at least part of the seal support surface and is attached to the seal support surface by over moulding, -- the support base portion comprises an annular base contact surface configured to, in use, contact an annular lip contact surface of the lip, -- the lip base portion and the support base portion are radially spaced from each other, and -- the lip and the support base portion are axially spaced from each other. - a main body having a longitudinal axis, at least one support portion having an at least partly radially extending annular seal support surface, and a tubular portion provided with protector threads configured to cooperate with the pipe threads of the pipe end, and - an annular flexible lip seal provided on the seal support surface, wherein; -- the main body is made from a first polymeric material having a first elastic modulus, -- the lip seal is made from a second polymeric material having a second elastic modulus which is lower than the first elastic modulus, and -- the lip seal comprises an annular lip base portion which extends radially along at least part of the seal support surface and is attached to the seal support surface by over moulding, -- the lip seal comprises an annular lip which extends from a foot of the lip being attached to the lip base portion to a free rim of the lip being axially spaced from the lip base portion, -- the foot and the free rim are radially offset, and characterised in that -- the lip seal is an axial lip seal, -- the axial lip seal comprises an annular support base portion which extends radially along at least part of the seal support surface and is attached to the seal support surface by over moulding, -- the support base portion comprises an annular base contact surface configured to, in use, contact an annular lip contact surface of the lip, -- the lip base portion and the support base portion are radially spaced from each other, and -- the lip and the support base portion are axially spaced from each other. -- the main body is made from a first polymeric material having a first elastic modulus, -- the lip seal is made from a second polymeric material having a second elastic modulus which is lower than the first elastic modulus, and -- the lip seal comprises an annular lip base portion which extends radially along at least part of the seal support surface and is attached to the seal support surface by over moulding, -- the lip seal comprises an annular lip which extends from a foot of the lip being attached to the lip base portion to a free rim of the lip being axially spaced from the lip base portion, -- the foot and the free rim are radially offset, and characterised in that -- the lip seal is an axial lip seal, -- the axial lip seal comprises an annular support base portion which extends radially along at least part of the seal support surface and is attached to the seal support surface by over moulding, -- the support base portion comprises an annular base contact surface configured to, in use, contact an annular lip contact surface of the lip, -- the lip base portion and the support base portion are radially spaced from each other, and -- the lip and the support base portion are axially spaced from each other.