mhurhangee/ep-ind-claims huggingface dataset:
A vehicle lighting fixture comprising: a plurality of light sources having a light emitting direction and arranged in a predetermined arranging direction orthogonal to the light emitting direction; a projector lens assembly (3, 4) disposed in front of the plurality of light sources and configured to project light emitted from the plurality of light sources forward; and an optical lens disposed within an optical path from the plurality of light sources to a position forward of the projector lens assembly (3, 4), wherein the optical lens includes a plurality of prisms (511A, 512A, 521A, 522A) configured to widen light source images of the plurality of light sources in the predetermined arranging direction, wherein the plurality of prisms (511A, 512A, 521A, 522A) each extend in a direction orthogonal to the arranging direction and are disposed side by side in the arranging direction or the plurality of prisms (511A, 512A, 521A, 522A) each extend in the arranging direction and are disposed side by side in a direction orthogonal to the arranging direction, characterized in that the plurality of prisms (511A, 512A, 521A, 522A) are each formed to have a triangular cross section orthogonal to the direction in which the prisms (511A, 512A, 521A, 522A) extend, and include two types of prisms (511A, 512A, 521A, 522A) having mutually different base angles in the triangular cross section and formed in a same surface of the optical lens, and the two types of prisms (511A, 512A, 521A, 522A) are configured such that a ratio of the base angles is 3:1. a plurality of light sources having a light emitting direction and arranged in a predetermined arranging direction orthogonal to the light emitting direction; a projector lens assembly (3, 4) disposed in front of the plurality of light sources and configured to project light emitted from the plurality of light sources forward; and an optical lens disposed within an optical path from the plurality of light sources to a position forward of the projector lens assembly (3, 4), wherein the optical lens includes a plurality of prisms (511A, 512A, 521A, 522A) configured to widen light source images of the plurality of light sources in the predetermined arranging direction, wherein the plurality of prisms (511A, 512A, 521A, 522A) each extend in a direction orthogonal to the arranging direction and are disposed side by side in the arranging direction or the plurality of prisms (511A, 512A, 521A, 522A) each extend in the arranging direction and are disposed side by side in a direction orthogonal to the arranging direction, characterized in that the plurality of prisms (511A, 512A, 521A, 522A) are each formed to have a triangular cross section orthogonal to the direction in which the prisms (511A, 512A, 521A, 522A) extend, and include two types of prisms (511A, 512A, 521A, 522A) having mutually different base angles in the triangular cross section and formed in a same surface of the optical lens, and the two types of prisms (511A, 512A, 521A, 522A) are configured such that a ratio of the base angles is 3:1.
An audio mixing console for processing of at least one audio signal, comprising: - a main housing with a plurality of outer surfaces, - a plurality of operating elements being provided on a first one of the outer surfaces to control the processing of the at least one audio signal, - a wireless transceiver provided substantially outside the main housing and configured for establishing wireless transmission of a first audio signal of the at least one audio signal, - an interface connected to the wireless transceiver and provided on one of the outer surfaces and configured for data forwarding of the first audio signal to and from the wireless transceiver, - a radio-frequency permeable housing detachably attached to a second one of the outer surfaces, wherein the wireless transceiver is positioned within the radio-frequency permeable housing, wherein the wireless transceiver extends in a vertical direction beyond a plane defined by the first outer surface. - a main housing with a plurality of outer surfaces, - a plurality of operating elements being provided on a first one of the outer surfaces to control the processing of the at least one audio signal, - a wireless transceiver provided substantially outside the main housing and configured for establishing wireless transmission of a first audio signal of the at least one audio signal, - an interface connected to the wireless transceiver and provided on one of the outer surfaces and configured for data forwarding of the first audio signal to and from the wireless transceiver, - a radio-frequency permeable housing detachably attached to a second one of the outer surfaces, wherein the wireless transceiver is positioned within the radio-frequency permeable housing,
A system comprising: a Reduced Instruction Set Computer (RISC) processor, wherein the RISC processor is adapted, responsive to receiving a request to process a Boolean operation, to execute a single processor data access instruction addressed to a region of a memory-mapped register to invoke said Boolean operation, said single processor data access instruction requiring no coprocessor interactions; wherein each address of each region of the memory-mapped register maps to a particular Boolean operation and to the location of the bits to be used in said Boolean operation; wherein said region of said memory-mapped register corresponding to said Boolean operations comprises an Intermediate Result area to store intermediate logic results; or in the case wherein said processor is comprised within a programmable logic controller, said region of said memory-mapped register corresponding to said Boolean operation comprises one of an Input Process Image area containing the state of physical input signals copied into the area by firmware of the PLC; or an Output Process Image area containing the results of logic decisions that can be copied out to physical output signals of the PLC by firmware of the PLC. a Reduced Instruction Set Computer (RISC) processor, wherein the RISC processor is adapted, responsive to receiving a request to process a Boolean operation, to execute a single processor data access instruction addressed to a region of a memory-mapped register to invoke said Boolean operation, said single processor data access instruction requiring no coprocessor interactions; wherein each address of each region of the memory-mapped register maps to a particular Boolean operation and to the location of the bits to be used in said Boolean operation; wherein said region of said memory-mapped register corresponding to said Boolean operations comprises an Intermediate Result area to store intermediate logic results; or in the case wherein said processor is comprised within a programmable logic controller,
A starter-drive generator system for starting an aircraft engine, the system comprising: a synchronous generator; a constant speed drive configured to perform a main engine start through the use of an external power supply and to perform a frequency control function; and a main bus, which is connectable to the external power supply during an engine start mode and to normal aircraft loads during a generate mode; characterised in that: the CSD comprises: a V-block wobbler and an FV-block wobbler; an F-unit servo to control an operation of the V-block wobbler; and an FV-unit servo to control an operation of the FV-block wobbler. a synchronous generator; a constant speed drive configured to perform a main engine start through the use of an external power supply and to perform a frequency control function; and a main bus, which is connectable to the external power supply during an engine start mode and to normal aircraft loads during a generate mode; characterised in that: the CSD comprises: a V-block wobbler and an FV-block wobbler; an F-unit servo to control an operation of the V-block wobbler; and an FV-unit servo to control an operation of the FV-block wobbler. a V-block wobbler and an FV-block wobbler; an F-unit servo to control an operation of the V-block wobbler; and an FV-unit servo to control an operation of the FV-block wobbler.
A surface-enhanced Raman scattering (SERS)-active photonic crystal fiber probe for integrated sample collection and SERS sensing of at least one analyte comprised in the sample, the probe comprising a biopsy needle and a plurality of SERS-active PCF fibers (PCFs) which are external to the biopsy needle and are arranged in longitudinal alignment with the biopsy needle around the biopsy needle, wherein the photonic crystal fiber has a longitudinal axis and comprises a solid core extending along the length of the longitudinal axis and a cladding in a region surrounding the solid core, wherein at least the cladding in the region comprises at least one air hole extending along the longitudinal axis of the photonic crystal fiber, wherein the inner surface of the at least one air hole is functionalized by metallic nanoparticles immobilized thereon that enhance Raman scattering, and the at least one air hole is configured for SERS sensing of the at least one analyte. wherein the photonic crystal fiber has a longitudinal axis and comprises a solid core extending along the length of the longitudinal axis and a cladding in a region surrounding the solid core, wherein at least the cladding in the region comprises at least one air hole extending along the longitudinal axis of the photonic crystal fiber, wherein the inner surface of the at least one air hole is functionalized by metallic nanoparticles immobilized thereon that enhance Raman scattering, and the at least one air hole is configured for SERS sensing of the at least one analyte.
A compound 4,4,4-trifluoro-N-[(lS)-2-[[ -5-(2-hydroxyethyl)-6-oxo-7H-pyrido[2,3-d] benzazepin-7-yl]amino]-1-methyl-2-oxo-ethyl]butanamide, or a pharmaceutically acceptable salt or hydrate thereof for use in a method of treating cancer, wherein said cancer is selected from the group consisting of T-cell acute lymphoblastic leukemia, acute lymphoblastic leukemia, chronic lymphoblastic leukemia, acute myelogenous leukemia, chronic myelogenous leukemia, erythroleukemia, triple negative breast cancer, breast cancer, ovarian cancer, melanoma, lung cancer, non small-cell lung cancer, pancreatic cancer, glioblastoma, colorectal cancer, head and neck cancer, cervical cancer, prostate cancer, liver cancer, oral squamous cell carcinoma, skin cancer, medulloblastoma, hepatocellular carcinoma, intrahepatic and extrahepatic cholangiocarcinoma, desmoid tumor, soft tissue sarcoma, and adenoid cystic carcinoma; wherein the method comprises administering 4,4,4-trifluoro-N-[ -2-[[ -5-(2-hydroxyethyl)-6-oxo-7H-pyrido[2,3-d] benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]butanamide, or a pharmaceutically acceptable salt or hydrate thereof in combination with a PD-1 or PD-L1 inhibitor selected from the group consisting of pembrolizumab, nivolumab, atezolizumab, durvalumab, and avelumab.
An oligonucleotide capable of inducing type I IFN production for use in inducing apoptosis of tumor cells through binding to RIG-I in the treatment of melanoma in a vertebrate animal, wherein the oligonucleotide comprises at least 1, preferably at least 3, more preferably at least 6 ribonucleotide(s) at the 5' end, a triphosphate group at the 5' end, and wherein the triphosphate group is free of any cap or modification, and wherein the oligonucleotide is at least 21 nucleotides in length, and wherein the oligonucleotide is a ligand of RIG-I. wherein the oligonucleotide comprises at least 1, preferably at least 3, more preferably at least 6 ribonucleotide(s) at the 5' end, a triphosphate group at the 5' end, and wherein the triphosphate group is free of any cap or modification, and wherein the oligonucleotide is at least 21 nucleotides in length, and wherein the oligonucleotide is a ligand of RIG-I.
A nucleic-acid-based detection method for diagnosing Bacterial Vaginosis in a subject, the method comprising: in a sample from a subject suspected of having BV performing an assay for the detection of select bacterial species in each of the genera Eggerthella and Prevotella and Lactobacillus but not L. iners in the sample, wherein the assay detects an Eggerthella species characterized by the presence of a 16S rRNA gene having a nucleobase sequence that is at least 98% identical to the sequence shown in SEQ ID NO:1 but does not detect other Eggerthella species, wherein the assay detects P. amnii, P. disiens, and P. bivia but does not detect other Prevotella species, and wherein if Lactobacillus is not detected, then the detection of at least one of Eggerthella and Prevotella indicates BV in the subject, and if Lactobacillus is detected, then the detection of both Eggerthella and Prevotella indicates BV in the subject. in a sample from a subject suspected of having BV performing an assay for the detection of select bacterial species in each of the genera Eggerthella and Prevotella and Lactobacillus but not L. iners in the sample, wherein the assay detects an Eggerthella species characterized by the presence of a 16S rRNA gene having a nucleobase sequence that is at least 98% identical to the sequence shown in SEQ ID NO:1 but does not detect other Eggerthella species, wherein the assay detects P. amnii, P. disiens, and P. bivia but does not detect other Prevotella species, and wherein if Lactobacillus is not detected, then the detection of at least one of Eggerthella and Prevotella indicates BV in the subject, and if Lactobacillus is detected, then the detection of both Eggerthella and Prevotella indicates BV in the subject.
A method comprising: requesting a management server from an end device for shortest path bridging, SPB, configuration information for the end device to communicate on an SPB network, wherein the end device is a non-SPB device that is not compatible with the SPB network and communicates with the management server over a non-SPB connection; receiving the SPB configuration information at the end device from the management server; and sending the SPB configuration information from the end device to an edge configuration device connected to the end device, wherein the SPB configuration information causes configuration of the edge configuration device to allow communication of the end device on the SPB network. requesting a management server from an end device for shortest path bridging, SPB, configuration information for the end device to communicate on an SPB network, wherein the end device is a non-SPB device that is not compatible with the SPB network and communicates with the management server over a non-SPB connection; receiving the SPB configuration information at the end device from the management server; and sending the SPB configuration information from the end device to an edge configuration device connected to the end device, wherein the SPB configuration information causes configuration of the edge configuration device to allow communication of the end device on the SPB network.
A pharmaceutical composition comprising curcumin monoglucuronide of the following formula (f): as an active component, for use as a medicament selected from an anti-cancer agent, an anti-inflammatory agent, a cholesterol-lowering agent, an anti-allergic agent, a cognitive function improving agent, and a heart disease preventive and therapeutic agent, wherein the medicament is administered intravenously.
A method of transmitting broadcasting data via transmit antennas, the method comprising: controlling a transmission power of data streams to be different based on a parameter α, which is a variable for controlling the transmission power of each data stream and has a value of between "0" and "1", wherein each one of the data streams is included in an input vector X, wherein: x = α x 1, 1 − α x 2 T; precoding the data streams of which the transmission power is controlled, using a precoding matrix that is determined based on a modulation scheme that is determined to be different for each of the transmit antennas; and transmitting each of the precoded data streams via corresponding each of the transmit antennas, and wherein the precoding matrix is determined according to Equation 1: Θ = cos ⁢ θ − sin ⁢ θ sin ⁢ θ cos ⁢ θ where Θ denotes the precoding matrix and θ denotes a rotation angle of the precoding matrix, wherein the rotation angle of the precoding matrix is 45 degree. controlling a transmission power of data streams to be different based on a parameter α, which is a variable for controlling the transmission power of each data stream and has a value of between "0" and "1", wherein each one of the data streams is included in an input vector X, wherein: x = α x 1, 1 − α x 2 T; precoding the data streams of which the transmission power is controlled, using a precoding matrix that is determined based on a modulation scheme that is determined to be different for each of the transmit antennas; and transmitting each of the precoded data streams via corresponding each of the transmit antennas, and wherein the precoding matrix is determined according to Equation 1: Θ = cos ⁢ θ − sin ⁢ θ sin ⁢ θ cos ⁢ θ where Θ denotes the precoding matrix and θ denotes a rotation angle of the precoding matrix, wherein the rotation angle of the precoding matrix is 45 degree.
A measurement tool for measuring a drill pipe section and/or elevator in a borehole drilling environment, the tool comprising a first leg, a second leg pivotally connected to the first leg, and a scale provided on the first leg, wherein a point at which the second leg intersects with the scale provides an indication of the value of at least one of the inner diameter of the bore of a drill pipe section and/or elevator in a borehole drilling environment, the outer diameter of the pipe section, and an angle of a surface of the pipe section and/or elevator relative to a datum surface thereof, and characterised in that a handle is provided on one of the legs (12, 14), and an actuating lever is provided on the other of the legs (12,14).
A compound of formula: wherein, -L-V-R is selected from: preferably, -L-V-R is selected from: -Ar 1 -L a -Ar 2 is selected from: and X 6 is CH or N; or a pharmaceutically acceptable salt, a stereoisomer, a solvate, a hydrate, a polymorph, or an isotopic variant thereof. X 6 is CH or N; or a pharmaceutically acceptable salt, a stereoisomer, a solvate, a hydrate, a polymorph, or an isotopic variant thereof.
A method to desalinate a process stream containing feed water, the method comprising: routing the process stream into a liquid pool zone of a vessel, the liquid pool zone including a heating medium, the heating medium being a liquid that is less volatile than the process stream and immiscible with the process stream and maintained at an operating temperature determined by vaporization requirements; vaporizing at least a portion of volatile components of the process stream due to heating of the process stream by contact with the heating medium in the liquid pool zone; removing a vaporized portion of the process stream from a vapor separation zone of the vessel as a vaporized process stream comprising steam; compressing the removed vaporized process stream to produce a pressurized process; condensing at least a portion of the pressurized process stream to produce a condensed process stream which is the desalinated water removing a portion of the heating medium and unvaporized process stream from the liquid pool zone of the vessel; separating the unvaporized process stream from the heating medium in the removed portion in a separator located in a pump around loop, wherein the separated unvaporized process stream includes solids; raising a temperature of the separated heating medium using heat recovered from condensing of the pressurized vaporized process stream to produce a heated recycle stream; and routing the heated recycle stream back to the liquid pool zone. routing the process stream into a liquid pool zone of a vessel, the liquid pool zone including a heating medium, the heating medium being a liquid that is less volatile than the process stream and immiscible with the process stream and maintained at an operating temperature determined by vaporization requirements; vaporizing at least a portion of volatile components of the process stream due to heating of the process stream by contact with the heating medium in the liquid pool zone; removing a vaporized portion of the process stream from a vapor separation zone of the vessel as a vaporized process stream comprising steam; compressing the removed vaporized process stream to produce a pressurized process; condensing at least a portion of the pressurized process stream to produce a condensed process stream which is the desalinated water removing a portion of the heating medium and unvaporized process stream from the liquid pool zone of the vessel; separating the unvaporized process stream from the heating medium in the removed portion in a separator located in a pump around loop, wherein the separated unvaporized process stream includes solids; raising a temperature of the separated heating medium using heat recovered from condensing of the pressurized vaporized process stream to produce a heated recycle stream; and routing the heated recycle stream back to the liquid pool zone.
An in vitro method of generating a library of DNA molecules encoding Cas9 single guide RNAs (sgRNAs) or Cas9 targeter RNAs, the method comprising: (a) contacting a target DNA molecule with a first DNA endonuclease that specifically binds to and cleaves within a recognition sequence that includes a Cas9 PAM sequence, to generate a plurality of cleavage fragments; (b) attaching a first DNA adapter to the plurality of cleavage fragments to generate a plurality of adapter-attached cleavage fragments, each having an adapter segment and a cleavage fragment segment; (c) contacting the plurality of adapter-attached cleavage fragments with a second DNA endonuclease that specifically binds to a recognition sequence present in the adapter segment and cleaves within the cleavage fragment segment to generate a plurality of adapter-attached Cas9 guide sequences each having an adapter segment and a guide sequence segment; (d) contacting the plurality of adapter-attached Cas9 guide sequences with a third DNA endonuclease that specifically binds to a recognition sequence present in the adapter segment and cleaves at one or more sites to remove all or a portion of the adapter segment, thereby generating a plurality of Cas9 guide sequences; and (e) attaching DNA encoding a constant region of a Cas9 sgRNA or a Cas9 targeter RNA to the plurality of Cas9 guide sequences to generate a library of DNA molecules encoding Cas9 sgRNAs or Cas9 targeter RNAs. (a) contacting a target DNA molecule with a first DNA endonuclease that specifically binds to and cleaves within a recognition sequence that includes a Cas9 PAM sequence, to generate a plurality of cleavage fragments; (b) attaching a first DNA adapter to the plurality of cleavage fragments to generate a plurality of adapter-attached cleavage fragments, each having an adapter segment and a cleavage fragment segment; (c) contacting the plurality of adapter-attached cleavage fragments with a second DNA endonuclease that specifically binds to a recognition sequence present in the adapter segment and cleaves within the cleavage fragment segment to generate a plurality of adapter-attached Cas9 guide sequences each having an adapter segment and a guide sequence segment; (d) contacting the plurality of adapter-attached Cas9 guide sequences with a third DNA endonuclease that specifically binds to a recognition sequence present in the adapter segment and cleaves at one or more sites to remove all or a portion of the adapter segment, thereby generating a plurality of Cas9 guide sequences; and (e) attaching DNA encoding a constant region of a Cas9 sgRNA or a Cas9 targeter RNA to the plurality of Cas9 guide sequences to generate a library of DNA molecules encoding Cas9 sgRNAs or Cas9 targeter RNAs.