Door of a cargo airplane, wherein a cargo compartment is accessible from the outside of the fuselage through an opening for loading goods provided with the door, the door being provided with: a first locking/unlocking device provided with a first operating handle accessible from the outside of the door and angularly movable between a first locking position and a second unlocking position and comprising a first transmission configured to transmit the rotation of the first handle to a first shaft angularly movable about its axis to control a locking/unlocking mechanism of pins that are in use used to connect the door to the fuselage and to control the closing/opening of a ventilation door connecting in use the cargo compartment with the outside of the fuselage; a first latching/unlatching device provided with a second operating handle accessible from the outside of the door and angularly movable between a first latching position and a second unlatching position and comprising a second transmission configured to transmit the rotation of the second handle to a second shaft angularly movable about its axis to operate a mechanism controlling the advancement/retraction of said pins in/from respective seats; characterized in that it comprises: a second locking/unlocking device provided with a third operating handle accessible from the inside of the door and angularly movable between a first locking position and a second unlocking position and comprising a third transmission configured to transmit the rotation of the third handle to the first shaft so that the first handle and the third handle are mechanically interconnected and control the same first shaft to allow locking/unlocking the pins and closing/opening the ventilation door; a second latching/unlatching device provided with a fourth operating handle accessible from the inside of the door and angularly movable between a first latching position and a second unlatching position and comprising a fourth transmission configured to transmit the rotation of the fourth handle to said second shaft so that the second handle and the fourth handle are mechanically interconnected and control the second shaft for advancing/retracting the pins in/from respective seats. a first locking/unlocking device provided with a first operating handle accessible from the outside of the door and angularly movable between a first locking position and a second unlocking position and comprising a first transmission configured to transmit the rotation of the first handle to a first shaft angularly movable about its axis to control a locking/unlocking mechanism of pins that are in use used to connect the door to the fuselage and to control the closing/opening of a ventilation door connecting in use the cargo compartment with the outside of the fuselage; a first latching/unlatching device provided with a second operating handle accessible from the outside of the door and angularly movable between a first latching position and a second unlatching position and comprising a second transmission configured to transmit the rotation of the second handle to a second shaft angularly movable about its axis to operate a mechanism controlling the advancement/retraction of said pins in/from respective seats; characterized in that it comprises: a second locking/unlocking device provided with a third operating handle accessible from the inside of the door and angularly movable between a first locking position and a second unlocking position and comprising a third transmission configured to transmit the rotation of the third handle to the first shaft so that the first handle and the third handle are mechanically interconnected and control the same first shaft to allow locking/unlocking the pins and closing/opening the ventilation door; a second latching/unlatching device provided with a fourth operating handle accessible from the inside of the door and angularly movable between a first latching position and a second unlatching position and comprising a fourth transmission configured to transmit the rotation of the fourth handle to said second shaft so that the second handle and the fourth handle are mechanically interconnected and control the second shaft for advancing/retracting the pins in/from respective seats. a second locking/unlocking device provided with a third operating handle accessible from the inside of the door and angularly movable between a first locking position and a second unlocking position and comprising a third transmission configured to transmit the rotation of the third handle to the first shaft so that the first handle and the third handle are mechanically interconnected and control the same first shaft to allow locking/unlocking the pins and closing/opening the ventilation door; a second latching/unlatching device provided with a fourth operating handle accessible from the inside of the door and angularly movable between a first latching position and a second unlatching position and comprising a fourth transmission configured to transmit the rotation of the fourth handle to said second shaft so that the second handle and the fourth handle are mechanically interconnected and control the second shaft for advancing/retracting the pins in/from respective seats.