A blood sampling transfer device adapted to receive a blood sample having a cellular portion and a plasma portion, the blood sampling transfer device comprising: a first component having two electrically driven internal miniature pumps and an actuation member including a two-way power switch; and a second component removably connected to the first component, the second component comprising: an inlet port, a flow channel, an outlet port, the inlet port and the outlet port in fluid communication via the flow channel, a tangential flow filter disposed within the flow channel between the inlet port and the outlet port, a first chamber defined between the inlet port and the tangential flow filter, and a transfer chamber defined between the tangential flow filter and the outlet port; wherein with the first component and the second component connected, the inlet port is adapted to receive the blood sample upon actuation of the two electrically driven internal miniature pumps, wherein the tangential flow filter is adapted to trap the cellular portion in the first chamber and allow the plasma portion to pass through the tangential flow filter and into the transfer chamber, characterized in that the tangential flow filter is adapted to utilize a cross-flow filtration to separate the plasma portion from the cellular portion, and wherein the two electrically driven internal miniature pumps are suitable to provide a mechanism to oscillate the blood sample back and forth over the tangential flow filter. a first component having two electrically driven internal miniature pumps and an actuation member including a two-way power switch; and a second component removably connected to the first component, the second component comprising: an inlet port, a flow channel, an outlet port, the inlet port and the outlet port in fluid communication via the flow channel, a tangential flow filter disposed within the flow channel between the inlet port and the outlet port, a first chamber defined between the inlet port and the tangential flow filter, and a transfer chamber defined between the tangential flow filter and the outlet port; wherein with the first component and the second component connected, the inlet port is adapted to receive the blood sample upon actuation of the two electrically driven internal miniature pumps, wherein the tangential flow filter is adapted to trap the cellular portion in the first chamber and allow the plasma portion to pass through the tangential flow filter and into the transfer chamber, an inlet port, a flow channel, an outlet port, the inlet port and the outlet port in fluid communication via the flow channel, a tangential flow filter disposed within the flow channel between the inlet port and the outlet port, a first chamber defined between the inlet port and the tangential flow filter, and a transfer chamber defined between the tangential flow filter and the outlet port; wherein with the first component and the second component connected, the inlet port is adapted to receive the blood sample upon actuation of the two electrically driven internal miniature pumps, wherein the tangential flow filter is adapted to trap the cellular portion in the first chamber and allow the plasma portion to pass through the tangential flow filter and into the transfer chamber,