A compound of the formula wherein: A is R is independently one or more hydrogen, CD 3, halogen, haloalkyl, hydroxyalkyl, CN, CF 3, CH 2 F, CHF 2, optionally substituted (C 1 -C 6)alkyl, optionally substituted (C 1 -C 6)alkoxy, optionally substituted (C 3 -C 6)cycloalkyl, -OR 4, -NR 3 R 4, NR 3 R 4 (C 1 -C 6)alkyl-, - NR 6 OCOR 3, -NR 6 COR 3 or NR 6 CONR 3 R 4; X and Y are independently selected from, optionally substituted aryl, optionally substituted heteroaryl or optionally substituted heterocyclo; Z is hydrogen, halogen, -OH, (C 1 -C 6)alkyl or (C 1 -C 6)alkoxy; R 1 is optionally substituted heteroaryl or optionally substituted 5-8 membered heterocyclyl; R 2 is hydrogen, halogen, optionally substituted (C 1 -C 6)alkyl, optionally substituted (C 1 -C 6) alkoxy, optionally substituted aryl, optionally substituted (C 1 -C 6)alkyl, -SO 2 optionally substituted 5-8 membered heteroaryl or optionally substituted 5-8 membered heterocyclo; R 3 is hydrogen, optionally substituted (C 1 -C 6)alkyl, optionally substituted (C 3 -C 8)cycloalkyl, optionally substituted (C 2 -C 6)alkenyl, optionally substituted (C 2 -C 6)alkynyl, cyano(C 1 -C 6)alkyl, hydroxy(C 1 -C 6)alkyl, optionally substituted aryl, optionally substituted aryl(C 1 -C 6)alkyl, optionally substituted aryloxy(C 1 -C 6)alkyl, optionally substituted (C 1 -C 6)alkyl-SO 2 -, optionally substituted heterocyclyl, optionally substituted heterocyclyl(C 1 -C 6)alkyl, optionally substituted heteroaryl or optionally substituted heteroaryl(C 1 -C 6)alkyl; R 4 is hydrogen, optionally substituted (C 1 -C 6)alkyl or optionally substituted (C 3 -C 8)cycloalkyl; R 6 is hydrogen, optionally substituted (C 1 -C 6)alkyl or optionally substituted (C 3 -C 8)cycloalkyl; or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof. A is R is independently one or more hydrogen, CD 3, halogen, haloalkyl, hydroxyalkyl, CN, CF 3, CH 2 F, CHF 2, optionally substituted (C 1 -C 6)alkyl, optionally substituted (C 1 -C 6)alkoxy, optionally substituted (C 3 -C 6)cycloalkyl, -OR 4, -NR 3 R 4, NR 3 R 4 (C 1 -C 6)alkyl-, - NR 6 OCOR 3, -NR 6 COR 3 or NR 6 CONR 3 R 4; X and Y are independently selected from, optionally substituted aryl, optionally substituted heteroaryl or optionally substituted heterocyclo; Z is hydrogen, halogen, -OH, (C 1 -C 6)alkyl or (C 1 -C 6)alkoxy; R 1 is optionally substituted heteroaryl or optionally substituted 5-8 membered heterocyclyl; R 2 is hydrogen, halogen, optionally substituted (C 1 -C 6)alkyl, optionally substituted (C 1 -C 6) alkoxy, optionally substituted aryl, optionally substituted (C 1 -C 6)alkyl, -SO 2 optionally substituted 5-8 membered heteroaryl or optionally substituted 5-8 membered heterocyclo; R 3 is hydrogen, optionally substituted (C 1 -C 6)alkyl, optionally substituted (C 3 -C 8)cycloalkyl, optionally substituted (C 2 -C 6)alkenyl, optionally substituted (C 2 -C 6)alkynyl, cyano(C 1 -C 6)alkyl, hydroxy(C 1 -C 6)alkyl, optionally substituted aryl, optionally substituted aryl(C 1 -C 6)alkyl, optionally substituted aryloxy(C 1 -C 6)alkyl, optionally substituted (C 1 -C 6)alkyl-SO 2 -, optionally substituted heterocyclyl, optionally substituted heterocyclyl(C 1 -C 6)alkyl, optionally substituted heteroaryl or optionally substituted heteroaryl(C 1 -C 6)alkyl; R 4 is hydrogen, optionally substituted (C 1 -C 6)alkyl or optionally substituted (C 3 -C 8)cycloalkyl; R 6 is hydrogen, optionally substituted (C 1 -C 6)alkyl or optionally substituted (C 3 -C 8)cycloalkyl; or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof.