A compound, or a pharmaceutically acceptable salt thereof, said compound having the structural Formula: or a tautomer thereof having the structural Formula (I'): or pharmaceutically acceptable salt thereof, wherein: R 1 is methyl; R 2 is hydrogen; R 3 is hydrogen; s is 0 or 1; when s is 0, then Y is absent and X is selected from the group consisting of -C(R 1X) 2 -, -O-, -S-, -S -, and -S 2 -, and when s is 1, then X is selected from the group consisting of -C(R 1X) 2 -, -O-, -S-, -S -, and -S 2 -, and Y is -C(R 1Y) 2 -, or, alternatively, when s is 1, then X is -C(R 1X) 2 - and Y is selected from the group consisting of -C(R 1Y) 2 -, -O-, -S-, -S -, and -S 2 -; each R 1X (when present) is independently selected from the group consisting of: H, halogen, alkyl, heteroalkyl, and cycloalkyl, wherein said alkyl, heteroalkyl, and cycloalkyl are each optionally independently unsubstituted or substituted with one or more halogen; each R 1Y (when present) is independently selected from the group consisting of: H, halogen, alkyl, heteroalkyl, and cycloalkyl, wherein said alkyl, heteroalkyl, and cycloalkyl are each optionally independently unsubstituted or substituted with one or more halogen; ring A is phenyl, pyridyl, thienyl, pyrimidinyl, or pyrazinyl; m is 0, 1 or 2; each R A (when present) is independently selected from the group consisting of: halogen, -CN, -SF 5, -NHCH 3, -N(CH 3) 2, -OCH 3, -OCH 2 CH 3, -O-cyclopropyl, -O-CH 2 -cyclopropyl, -CH 2 OCH 3, -S(CH 3), methyl, ethyl, cyclopropyl, -CH 2 -cyclopropyl, -C≡C-CH 3, -CF 3, -CHF 2, -CH 2 F, -OCF 3, and -OCHF 2; -L 1 - represents -C NH-; R L is selected from the group consisting of C 1-4 alkyl and C 1-4 heteroalkyl, wherein said alkyl and heteroalkyl of R L are each optionally unsubstituted or substituted with one or more halogen; or, alternatively, R L is a moiety having the formula wherein ring B is selected from the group consisting of isoxazolyl, oxadiazoyl, oxazolyl, phenyl, pyridinyl, pyrazinyl, pyrimidinyl, and pyrazolyl; p is 0 or more; and each R B group (when present) is independently selected from the group consisting of fluoro, chloro, bromo, -CN, -S 2 CH 3, -OCH 3, -O-cyclopropyl, -O-CH 2 -cyclopropyl, -OCH 2 -C≡C-H, -OCH 2 -C≡C-CH 3, methyl, cyclopropyl, -CH 2 -cyclopropyl, -CH 2 OCH 3, -C≡CH, -C≡C-CH 3, -CF 3, -CHF 2, -CH 2 F, -OCF 3, -OCHF 2, -OCH 2 F, and -OCH 2 CH 2 F. R 1 is methyl; R 2 is hydrogen; R 3 is hydrogen; s is 0 or 1; when s is 0, then Y is absent and X is selected from the group consisting of -C(R 1X) 2 -, -O-, -S-, -S -, and -S 2 -, and when s is 1, then X is selected from the group consisting of -C(R 1X) 2 -, -O-, -S-, -S -, and -S 2 -, and Y is -C(R 1Y) 2 -, or, alternatively, when s is 1, then X is -C(R 1X) 2 - and Y is selected from the group consisting of -C(R 1Y) 2 -, -O-, -S-, -S -, and -S 2 -; each R 1X (when present) is independently selected from the group consisting of: H, halogen, alkyl, heteroalkyl, and cycloalkyl, wherein said alkyl, heteroalkyl, and cycloalkyl are each optionally independently unsubstituted or substituted with one or more halogen; each R 1Y (when present) is independently selected from the group consisting of: H, halogen, alkyl, heteroalkyl, and cycloalkyl, wherein said alkyl, heteroalkyl, and cycloalkyl are each optionally independently unsubstituted or substituted with one or more halogen; ring A is phenyl, pyridyl, thienyl, pyrimidinyl, or pyrazinyl; m is 0, 1 or 2; each R A (when present) is independently selected from the group consisting of: halogen, -CN, -SF 5, -NHCH 3, -N(CH 3) 2, -OCH 3, -OCH 2 CH 3, -O-cyclopropyl, -O-CH 2 -cyclopropyl, -CH 2 OCH 3, -S(CH 3), methyl, ethyl, cyclopropyl, -CH 2 -cyclopropyl, -C≡C-CH 3, -CF 3, -CHF 2, -CH 2 F, -OCF 3, and -OCHF 2; -L 1 - represents -C NH-; R L is selected from the group consisting of C 1-4 alkyl and C 1-4 heteroalkyl, wherein said alkyl and heteroalkyl of R L are each optionally unsubstituted or substituted with one or more halogen; or, alternatively, R L is a moiety having the formula wherein ring B is selected from the group consisting of isoxazolyl, oxadiazoyl, oxazolyl, phenyl, pyridinyl, pyrazinyl, pyrimidinyl, and pyrazolyl; p is 0 or more; and each R B group (when present) is independently selected from the group consisting of fluoro, chloro, bromo, -CN, -S 2 CH 3, -OCH 3, -O-cyclopropyl, -O-CH 2 -cyclopropyl, -OCH 2 -C≡C-H, -OCH 2 -C≡C-CH 3, methyl, cyclopropyl, -CH 2 -cyclopropyl, -CH 2 OCH 3, -C≡CH, -C≡C-CH 3, -CF 3, -CHF 2, -CH 2 F, -OCF 3, -OCHF 2, -OCH 2 F, and -OCH 2 CH 2 F.