mhurhangee/ep-ind-claims huggingface dataset:
A surgical instrument for driving elongated pins or wires, the instrument comprising; a body; a first shaft having a lumen substantially concentric about a longitudinal axis (L-L), the first shaft being rotatable about the longitudinal axis and positioned at least partially within the body; a second shaft at least partially positioned around the first shaft and positioned at least partially within the body, the second shaft being axially mobile and comprising a first ramped surface and a second ramped surface positioned a distance distal from the first ramped surface; an actuator member in communication with the second shaft; a first holding feature located adjacent a first position along the longitudinal axis, wherein the first holding feature is configured to passively and constantly apply a first force to an elongated member received in the lumen of the first shaft; and a second holding feature (32b/32c), comprising a set of engaging features and the ramped surfaces (52a,52b) of the second shaft, where the second holding feature is configured to actively and selectively apply a second force to the elongated member received in the lumen of the first shaft in response to activation of the actuator member which causes axial movement of the second shaft relative to the first shaft and engagement of the set of engagement features by the ramped surfaces of the second shaft. a body; a first shaft having a lumen substantially concentric about a longitudinal axis (L-L), the first shaft being rotatable about the longitudinal axis and positioned at least partially within the body; a second shaft at least partially positioned around the first shaft and positioned at least partially within the body, the second shaft being axially mobile and comprising a first ramped surface and a second ramped surface positioned a distance distal from the first ramped surface; an actuator member in communication with the second shaft; a first holding feature located adjacent a first position along the longitudinal axis, wherein the first holding feature is configured to passively and constantly apply a first force to an elongated member received in the lumen of the first shaft; and a second holding feature (32b/32c), comprising a set of engaging features and the ramped surfaces (52a,52b) of the second shaft, where the second holding feature is configured to actively and selectively apply a second force to the elongated member received in the lumen of the first shaft in response to activation of the actuator member which causes axial movement of the second shaft relative to the first shaft and engagement of the set of engagement features by the ramped surfaces of the second shaft.
An apparatus used in a Self-Organizing Network, SON, the apparatus comprising: first execution means for executing a first Self-Organizing Network, SON, operation on: a first cell of a base station, a second cell adjacent to the first cell, or a neighboring cell pair consisting of the first and second cells (40, 41), the first SON operation including repeatedly adjusting a configuration parameter that affects an operation of one or both of the base station and a mobile station to achieve an optimization objective regarding a radio network; and exclusion means for excluding: the first cell, the second cell, or the neighboring cell pair from future execution of the first SON operation, if achievement status of the optimization objective after completion of the first SON operation does not satisfy a predetermined reference level. first execution means for executing a first Self-Organizing Network, SON, operation on: a first cell of a base station, a second cell adjacent to the first cell, or a neighboring cell pair consisting of the first and second cells (40, 41), the first SON operation including repeatedly adjusting a configuration parameter that affects an operation of one or both of the base station and a mobile station to achieve an optimization objective regarding a radio network; and exclusion means for excluding: the first cell, the second cell, or the neighboring cell pair from future execution of the first SON operation, if achievement status of the optimization objective after completion of the first SON operation does not satisfy a predetermined reference level.
A pneumatic tire having a tread portion, plural tread grooves (5, 15) including a first tread groove and a second tread groove formed in the tread portion, and a first bottom-up portion with a top surface as a tread wear indicator, the first bottom-up portion being provided at a groove bottom of the first tread groove such that a distance measured in the tire radial direction from an opening end position of the first tread groove to the top surface is x1, comprising: a second bottom-up portion with a top surface as a retread indicator, the second bottom-up portion being provided at a groove bottom of the second tread groove formed in the central region of the tread portion such that a distance measured in the tire radial direction from an opening end position of the second tread groove to the top surface is x2 shorter than said x1, characterized in that provided that d1 is the groove depth of the first tread groove, d1 - x2 ≥ 3.0 mm. a second bottom-up portion with a top surface as a retread indicator, the second bottom-up portion being provided at a groove bottom of the second tread groove formed in the central region of the tread portion such that a distance measured in the tire radial direction from an opening end position of the second tread groove to the top surface is x2 shorter than said x1, characterized in that provided that d1 is the groove depth of the first tread groove, d1 - x2 ≥ 3.0 mm.
A therapy system for applying therapy signals to the dorsal column of a patient's spinal region, comprising: an implantable pulse generator; and at least one signal delivery device connected to the implantable pulse generator via a lead body and having multiple electrodes, wherein the implantable pulse generator generates a high frequency biphasic therapy signal having a frequency in the range of from 2,500 Hz to 100,000 Hz and the high frequency therapy signal is applied in place of a low frequency stimulation signal, having a frequency in a range of up to 1,500 Hz and a pulse width equal to or less than half of the period of the signal, to replace the pain relief provided by paresthesia. an implantable pulse generator; and at least one signal delivery device connected to the implantable pulse generator via a lead body and having multiple electrodes, wherein the implantable pulse generator generates a high frequency biphasic therapy signal having a frequency in the range of from 2,500 Hz to 100,000 Hz and the high frequency therapy signal is applied in place of a low frequency stimulation signal, having a frequency in a range of up to 1,500 Hz and a pulse width equal to or less than half of the period of the signal, to replace the pain relief provided by paresthesia.
A method of managing articulation in a motor grader having front wheels (58, 60) that are steerable, the front wheels (58, 60) attached to a front frame, the front frame and a rear frame pivotally connected at an articulation joint, the method comprising: determining, at a controller, a steering angle of the front wheels (58, 60); characterised by the step of adjusting, via the controller, an articulation angle at the articulation joint at a first ratio of more than one degree of the steering angle to one degree of articulation angle, wherein adjusting the articulation angle further comprises adjusting the articulation angle at a second ratio less than the first ratio for steering angles in a second range; and adjusting the articulation angle at the first ratio for steering angles in a first range. determining, at a controller, a steering angle of the front wheels (58, 60); characterised by the step of adjusting, via the controller, an articulation angle at the articulation joint at a first ratio of more than one degree of the steering angle to one degree of articulation angle, wherein adjusting the articulation angle further comprises adjusting the articulation angle at a second ratio less than the first ratio for steering angles in a second range; and adjusting the articulation angle at the first ratio for steering angles in a first range.
A food treated with a bacteriophage, the treated food comprising: a food product; a first, fatty or waxy coating layer on the food product; and a second coating layer comprising one or more bacteriophage strains, wherein the fatty or waxy coating layer is distinct from the coating layer comprising the one or more bacteriophage strains, wherein the coating layer comprising the one or more bacteriophage strains is the outermost coating layer on the food. a food product; a first, fatty or waxy coating layer on the food product; and a second coating layer comprising one or more bacteriophage strains,
A plumbing arrangement element with a pipe mount for connecting a first pipe section of the plumbing arrangement element as a first plumbing arrangement element to a second pipe section of a second plumbing arrangement element to form a continuous vertical pipeline, the pipe mount arranged inside the plumbing arrangement element, characterized in that the pipe mount comprises - a sliding member configured to be movably attached to the plumbing arrangement element, the sliding member configured to extend in the vertical direction of the plumbing arrangement element, and the sliding member configured to be vertically movable between an extreme position and a second position; and - at least one pipe bracket extending horizontally from the sliding member, the at least one pipe bracket configured to secure the first pipe section onto the sliding member, the first pipe section configured to extend vertically from a bottom part of the plumbing arrangement element to a top part of the plumbing arrangement element - a sliding member configured to be movably attached to the plumbing arrangement element, the sliding member configured to extend in the vertical direction of the plumbing arrangement element, and the sliding member configured to be vertically movable between an extreme position and a second position; and - at least one pipe bracket extending horizontally from the sliding member, the at least one pipe bracket configured to secure the first pipe section onto the sliding member, the first pipe section configured to extend vertically from a bottom part of the plumbing arrangement element to a top part of the plumbing arrangement element
A method of additively manufacturing an article comprising: forming a first portion of the article by additively manufacturing a plurality of first layers from a first powder material cut having a first average particle size corresponding to a first feature resolution, the plurality of first layers having a first average layer thickness; and forming a second portion of the article by additively manufacturing a plurality of second layers from a second powder material cut having a second average particle size corresponding to a second feature resolution less than the first feature resolution, the second portion comprising at least one feature, the plurality of second layers having a second average layer thickness less than the first average layer thickness; wherein the first powder material cut is stored in a first hopper; the second powder material cut is stored in a second hopper; and forming the first and second portions (210, 220) comprises selectively delivering, by a powder delivery assembly, the first powder material cut from the first hopper to a printing platform and the second powder material cut from the second hopper to the printing platform, wherein the powder delivery assembly comprises at least one powder material feeder that deposits and spreads the material of the first powder material cut or the second powder material cut across a surface of a powder bed above a printing platform as a new layer to be sintered or melted. forming a first portion of the article by additively manufacturing a plurality of first layers from a first powder material cut having a first average particle size corresponding to a first feature resolution, the plurality of first layers having a first average layer thickness; and forming a second portion of the article by additively manufacturing a plurality of second layers from a second powder material cut having a second average particle size corresponding to a second feature resolution less than the first feature resolution, the second portion comprising at least one feature, the plurality of second layers having a second average layer thickness less than the first average layer thickness; wherein the first powder material cut is stored in a first hopper; the second powder material cut is stored in a second hopper; and forming the first and second portions (210, 220) comprises selectively delivering, by a powder delivery assembly, the first powder material cut from the first hopper to a printing platform and the second powder material cut from the second hopper to the printing platform, wherein the powder delivery assembly comprises at least one powder material feeder that deposits and spreads the material of the first powder material cut or the second powder material cut across a surface of a powder bed above a printing platform as a new layer to be sintered or melted.
A method of operating a hearing aid system comprising the steps of: - measuring the electrical impedance of a hearing aid receiver for a given frequency and for a range of different bias voltages applied to the hearing aid receiver, - deriving values of a non-linear hearing aid receiver parameter for the range of different bias voltages, - using the derived values of the non-linear hearing aid receiver parameter to estimate a measure of the non-linearity of the hearing aid receiver, - triggering an action directed at alerting a hearing aid system user or directed at compensating the non-linearity of the hearing aid receiver if the estimated measure of the non-linearity exceeds a predetermined threshold. - measuring the electrical impedance of a hearing aid receiver for a given frequency and for a range of different bias voltages applied to the hearing aid receiver, - deriving values of a non-linear hearing aid receiver parameter for the range of different bias voltages, - using the derived values of the non-linear hearing aid receiver parameter to estimate a measure of the non-linearity of the hearing aid receiver, - triggering an action directed at alerting a hearing aid system user or directed at compensating the non-linearity of the hearing aid receiver if the estimated measure of the non-linearity exceeds a predetermined threshold.
A method of making a three-dimensional glass article, comprising: a. forming at least one notch on an edge of a two-dimensional glass piece; b. aligning the 2D glass piece on a mold by contacting an alignment pin on the mold with the at least one notch formed on the edge of the 2D glass piece; thermally reforming a 2D glass piece into a 3D glass article, wherein the at least one notch formed on the edge of the 2D glass piece is carried over to an edge of the 3D glass article; c. aligning the 3D glass article on a support using the at least one notch on the edge of the 3D glass article by contacting an alignment pin on the support with the notch on the edge of the 3D glass article; d. securing the 3D glass article to the support, removing the alignment pin from the at least one notch; and e. finishing the edge of the 3D glass article to a final shape and dimension and removing the at least one notch from the 3D glass article. a. forming at least one notch on an edge of a two-dimensional glass piece; b. aligning the 2D glass piece on a mold by contacting an alignment pin on the mold with the at least one notch formed on the edge of the 2D glass piece; thermally reforming a 2D glass piece into a 3D glass article, wherein the at least one notch formed on the edge of the 2D glass piece is carried over to an edge of the 3D glass article; c. aligning the 3D glass article on a support using the at least one notch on the edge of the 3D glass article by contacting an alignment pin on the support with the notch on the edge of the 3D glass article; d. securing the 3D glass article to the support, removing the alignment pin from the at least one notch; and e. finishing the edge of the 3D glass article to a final shape and dimension and removing the at least one notch from the 3D glass article.
A package comprising a protective film enclosing an article and a tack label coupled to an outer surface of the protective film, wherein the protective film includes an overlapping portion in which a first edge portion directly opposing the article and a second edge portion opposing the article via the first edge portion are overlapped with each other, the tack label is coupled so as to cover the overlapping portion characterized in that in a coupling surface between the protective film 5 and the tack label, a non-uniform coupling force distribution is provided in which a second region that is continuously connected to the second edge portion has a higher coupling force than a first region that is continuously connected to the first edge portion.
A method of preparing dolutegravir of Formula I, comprising: a) reacting the compound of Formula II or a reactive derivative thereof with 2,4-difluoro benzylamine to provide a compound of Formula III, wherein R is alkyl, aryl or aralkyl group, P 1 and P 2 independently represent a ketal protecting group, or together form a cyclic ring; b) deprotecting the compound of Formula III to provide a compound of Formula IV; c) converting the compound of Formula IV into a compound of Formula V; d) reacting the compound of Formula V with a compound of Formula VI to provide a compound of Formula VII, wherein R 1 and R 2 independently represent an alkyl; e) condensing the compound of Formula VII with a compound of Formula VIII to provide a compound of Formula IX, wherein R 3 and R 4 are independently alkyl, aryl or aralkyl; f) converting the compound of Formula IX into a compound of Formula X; g) reacting the compound of Formula X with -3-amino-1-butanol to provide a compound of Formula XI; and h) converting the compound of Formula XI into dolutegravir of Formula I. a) reacting the compound of Formula II or a reactive derivative thereof with 2,4-difluoro benzylamine to provide a compound of Formula III, wherein R is alkyl, aryl or aralkyl group, P 1 and P 2 independently represent a ketal protecting group, or together form a cyclic ring; wherein R is alkyl, aryl or aralkyl group, P 1 and P 2 independently represent a ketal protecting group, or together form a cyclic ring; b) deprotecting the compound of Formula III to provide a compound of Formula IV; c) converting the compound of Formula IV into a compound of Formula V; d) reacting the compound of Formula V with a compound of Formula VI to provide a compound of Formula VII, wherein R 1 and R 2 independently represent an alkyl; e) condensing the compound of Formula VII with a compound of Formula VIII to provide a compound of Formula IX, wherein R 3 and R 4 are independently alkyl, aryl or aralkyl; f) converting the compound of Formula IX into a compound of Formula X; g) reacting the compound of Formula X with -3-amino-1-butanol to provide a compound of Formula XI; and h) converting the compound of Formula XI into dolutegravir of Formula I.
Process for production of -3-Quinuclidinol or a salt thereof by reduction of Quinuclidin-3-one with cofactor and oxidoreductase, characterized in that, the oxidoreductase comprises an amino acid sequence motif MQX 1 REX 2 X 3 WEA, wherein each of X 1, X 2, X 3 are any of amino acid residues A (Ala), R (Arg), N (Asn), D (Asp), C (Cys), Q (Gln), E (Glu), G (Gly), H (His), I (Ile), L (Leu), K (Lys), M (Met), F (Phe), P (Pro), S (Ser), T (Thr), W (Trp), Y (Tyr) or V (Val), and in that the oxidoreductase is selected from a) polypeptides with an amino acid sequence, wherein at least 65 % of the amino acids are identical to the amino acids of SEQ ID NO: 1 or SEQ ID NO:3; or b) polypeptides with an amino acid sequence, wherein at least 75 % of the amino acids are identical to the amino acids of SEQ ID NO:5 or SEQ ID NO:9; or c) polypeptides with an amino acid sequence, wherein at least 85 % of amino acids are identical to the amino acids of SEQ ID NO:7. a) polypeptides with an amino acid sequence, wherein at least 65 % of the amino acids are identical to the amino acids of SEQ ID NO: 1 or SEQ ID NO:3; or b) polypeptides with an amino acid sequence, wherein at least 75 % of the amino acids are identical to the amino acids of SEQ ID NO:5 or SEQ ID NO:9; or c) polypeptides with an amino acid sequence, wherein at least 85 % of amino acids are identical to the amino acids of SEQ ID NO:7.
A hearing aid for enhancing speech intelligibility, the hearing aid comprising: - an input transducer for providing an input signal (12,14) comprising a speech signal and a noise signal; - a processing unit configured for processing the input signal (12,14); - an acoustic output transducer coupled to an output of the processing unit for conversion of an output signal from the processing unit into an audio output signal; wherein the processing unit is configured for performing a codebook based approach processing on the input signal (12,14), where the processing unit is configured for determining one or more parameters of the input signal (12,14) based on the codebook based approach processing, where the processing unit is configured for performing a Kalman filtering of the input signal (12,14) using the determined one or more parameters, where the processing unit is configured to provide that the output signal is speech intelligibility enhanced due to the Kalman filtering. - an input transducer for providing an input signal (12,14) comprising a speech signal and a noise signal; - a processing unit configured for processing the input signal (12,14); - an acoustic output transducer coupled to an output of the processing unit for conversion of an output signal from the processing unit into an audio output signal; wherein the processing unit is configured for performing a codebook based approach processing on the input signal (12,14),
A method for cryptographically encrypting an electronic text message in a mobile terminal, wherein the text message is sent via a mobile communication network to a remote receiver entity after the encryption, having the method steps of: - establishing a communication channel via the mobile communication network to an entity by a security element in the mobile terminal; characterized in that the entity is a mobile communication certificate entity, and - receiving at least a subset of a certificate from the mobile communication certificate entity via the established communication channel in the mobile communication network by the security element, wherein the certificate is reduced so that the subset of the certificate thus contains an allocation information item of the remote receiver entity and a public key part of an asymmetric key pair of the remote receiver entity; and - encrypting the text message employing the subset of the received certificate by the mobile terminal or the security element. - establishing a communication channel via the mobile communication network to an entity by a security element in the mobile terminal; - receiving at least a subset of a certificate from the mobile communication certificate entity via the established communication channel in the mobile communication network by the security element, wherein the certificate is reduced so that the subset of the certificate thus contains an allocation information item of the remote receiver entity and a public key part of an asymmetric key pair of the remote receiver entity; and - encrypting the text message employing the subset of the received certificate by the mobile terminal or the security element.