An orthopedic brace (100, 200, 300, 301, 302, 303), comprising: a pair of back panels (102, 104, 202, 204, 302, 304), each having a dorsal end (120, 220, 320) and a lateral end (122, 222, 322) the pair of back panels configured such that the dorsal ends of each back panel are proximate one another and capable of being positioned on the lower back of a wearer, with the back panels capable of wrapping around the wearer such that the lateral ends of each back panel are generally positioned on the side of the wearer; a closure system (110, 111, 210, 310, 311), including a tensioning mechanism (160, 260, 360, 361), a lace 162, 262, 362, 363), and a plurality of lace guides (166, 266, 366, 368), the lace being coupled to the tensioning mechanism and guided by the lace guides, and at least one lace guide is positioned generally on the dorsal end of each back panel; a pair of front panels (106, 108, 206, 208, 306, 308), each having a lateral end (140, 240, 340) and a ventral end (142, 242, 342), the lateral end of each front panel releasably coupleable to the lateral end of each back panel such that each front panel is configured to extend generally from the side of the wearer around the front of the wearer, and the ventral end of each front panel includes an attachment means (156, 256, 356) configured to allow one of the front panels to releasably attach to the other of the front panels generally over an abdomen of a wearer; wherein an angle between the front panels with respect to the back panels may be adjusted by attaching the lateral end of each front panel to the lateral end of each back panel at a desired angle. a pair of back panels (102, 104, 202, 204, 302, 304), each having a dorsal end (120, 220, 320) and a lateral end (122, 222, 322) the pair of back panels configured such that the dorsal ends of each back panel are proximate one another and capable of being positioned on the lower back of a wearer, with the back panels capable of wrapping around the wearer such that the lateral ends of each back panel are generally positioned on the side of the wearer; a closure system (110, 111, 210, 310, 311), including a tensioning mechanism (160, 260, 360, 361), a lace 162, 262, 362, 363), and a plurality of lace guides (166, 266, 366, 368), the lace being coupled to the tensioning mechanism and guided by the lace guides, and at least one lace guide is positioned generally on the dorsal end of each back panel; a pair of front panels (106, 108, 206, 208, 306, 308), each having a lateral end (140, 240, 340) and a ventral end (142, 242, 342), the lateral end of each front panel releasably coupleable to the lateral end of each back panel such that each front panel is configured to extend generally from the side of the wearer around the front of the wearer, and the ventral end of each front panel includes an attachment means (156, 256, 356) configured to allow one of the front panels to releasably attach to the other of the front panels generally over an abdomen of a wearer; wherein an angle between the front panels with respect to the back panels may be adjusted by attaching the lateral end of each front panel to the lateral end of each back panel at a desired angle.