mhurhangee/ep-ind-claims huggingface dataset:
A virus-like particle obtainable by (a) transfecting a human cell with a modified EBV genome, wherein said modified EBV genome in comparison to a wildtype EBV genome at least (aa) lacks one or more sequences that are required for the packaging of said wildtype EBV genome, lacks one or more sequences encoding EBV polypeptides required for said packaging and/or comprises one or more sequences encoding EBV polypeptides whose packaging capacity is disabled; (ab) lacks one or more sequences encoding EBV polypeptides that are required for B-cell transformation and/or comprises one or more sequences encoding EBV polypeptides whose B-cell transformation capacity is disabled; and (ac) lacks one or more sequences encoding EBV polypeptides that are required for inducing replication of an EBV and/or comprises one or more sequences encoding EBV polypeptides whose capacity for inducing EBV replication is disabled; (b) culturing the cell obtained in step (a) under conditions that allow expression of said modified EBV genome; (c) inducing the replicative phase of EBV; and (d) isolating said particle for use in a method for eliciting a therapeutic or prophylactic EBV-specific CD8+ cellular immune response and a humoral immune response in a human individual, said method comprising administering said particle to said human individual. (a) transfecting a human cell with a modified EBV genome, wherein said modified EBV genome in comparison to a wildtype EBV genome at least (aa) lacks one or more sequences that are required for the packaging of said wildtype EBV genome, lacks one or more sequences encoding EBV polypeptides required for said packaging and/or comprises one or more sequences encoding EBV polypeptides whose packaging capacity is disabled; (ab) lacks one or more sequences encoding EBV polypeptides that are required for B-cell transformation and/or comprises one or more sequences encoding EBV polypeptides whose B-cell transformation capacity is disabled; and (ac) lacks one or more sequences encoding EBV polypeptides that are required for inducing replication of an EBV and/or comprises one or more sequences encoding EBV polypeptides whose capacity for inducing EBV replication is disabled; (aa) lacks one or more sequences that are required for the packaging of said wildtype EBV genome, lacks one or more sequences encoding EBV polypeptides required for said packaging and/or comprises one or more sequences encoding EBV polypeptides whose packaging capacity is disabled; (ab) lacks one or more sequences encoding EBV polypeptides that are required for B-cell transformation and/or comprises one or more sequences encoding EBV polypeptides whose B-cell transformation capacity is disabled; and (ac) lacks one or more sequences encoding EBV polypeptides that are required for inducing replication of an EBV and/or comprises one or more sequences encoding EBV polypeptides whose capacity for inducing EBV replication is disabled; (b) culturing the cell obtained in step (a) under conditions that allow expression of said modified EBV genome; (c) inducing the replicative phase of EBV; and (d) isolating said particle
A multimodal polyethylene composition comprising; 35 to 65 percent by weight, preferably 45 to 65 percent by weight, most preferred 50 to 60 percent by weight, of the low molecular weight polyethylene homopolymer having a density of > 0.965 g/cm 3, a MI 2 in the range from 10 to 1,000 g/10 min, and a weight average molecular weight (Mw) of 20,000 to 90,000 g/mol; 5 to 40 percent by weight, preferably 5 to 30 parts by weight, most preferred 5 to 20 percent by weight, of the first high molecular weight polyethylene having a weight average molecular weight (Mw) of more than 150,000 to 1,000,000g/mol or the first ultra high molecular weight polyethylene having a weight average molecular weight (Mw) of more than 1,000,000 to 5,000,000g/mol; and 20 to 60 percent by weight, preferably 25 to 60 percent by weight, most preferred 35 to 55 percent by weight, of the second high molecular weight polyethylene having a weight average molecular weight (Mw) of more than 150,000 to 1,000,000g/mol or the second ultra high molecular weight polyethylene having a weight average molecular weight (Mw) of more than 1,000,000 to 5,000,000g/mol, wherein the molecular weight distribution of the multimodal polyethylene composition is from 10 to 25, preferably 10 to 20, determined by Gel Permeation Chromatography; the isothermal crystallization half-time of the multimodal polyethylene composition at a temperature of 123°C is 6 min or less, preferably 2-6 min, according to Differential Scanning Calorimetry; and a spiral flow length at a temperature of 220°C is at least 200 mm, preferably 250-400 mm. 35 to 65 percent by weight, preferably 45 to 65 percent by weight, most preferred 50 to 60 percent by weight, of the low molecular weight polyethylene homopolymer having a density of > 0.965 g/cm 3, a MI 2 in the range from 10 to 1,000 g/10 min, and a weight average molecular weight (Mw) of 20,000 to 90,000 g/mol; 5 to 40 percent by weight, preferably 5 to 30 parts by weight, most preferred 5 to 20 percent by weight, of the first high molecular weight polyethylene having a weight average molecular weight (Mw) of more than 150,000 to 1,000,000g/mol or the first ultra high molecular weight polyethylene having a weight average molecular weight (Mw) of more than 1,000,000 to 5,000,000g/mol; and 20 to 60 percent by weight, preferably 25 to 60 percent by weight, most preferred 35 to 55 percent by weight, of the second high molecular weight polyethylene having a weight average molecular weight (Mw) of more than 150,000 to 1,000,000g/mol or the second ultra high molecular weight polyethylene having a weight average molecular weight (Mw) of more than 1,000,000 to 5,000,000g/mol,
An apparatus for delivering electromagnetic radiation to an anterior surface of an iris of a human eye, the apparatus comprising: an electromagnetic radiation generator comprising a laser for generating a laser beam; and a computerized scanning system to apply the laser beam to 50% or more of the total area of the anterior surface of the iris; characterized in that the electromagnetic radiation generator is configured to emit a laser beam which converges to a focal point on the iris and delivers to the iris a first energy density, wherein in the event of accidental exposure of the fundus to the laser beam, the laser beam diverges posterior to the iris at a divergence angle not less than 2.5 degrees and delivers to the fundus a second energy density, and wherein the first energy density is greater than the second energy density. an electromagnetic radiation generator comprising a laser for generating a laser beam; and a computerized scanning system to apply the laser beam to 50% or more of the total area of the anterior surface of the iris; characterized in that the electromagnetic radiation generator is configured to emit a laser beam which converges to a focal point on the iris and delivers to the iris a first energy density, wherein in the event of accidental exposure of the fundus to the laser beam, the laser beam diverges posterior to the iris at a divergence angle not less than 2.5 degrees and delivers to the fundus a second energy density, and wherein the first energy density is greater than the second energy density.
Method for operating an internal combustion engine with a turbocharger arrangement comprising a low-pressure and a high-pressure stage arranged sequentially, the low-pressure stage comprising a low-pressure compressor, and at least one turbocharger control valve (15, 16) operable by a supply system, the method comprising calculating an engine control parameter setpoint, detecting a supply system failure and, if no failure of the supply system has been detected, employing the calculated engine control parameter setpoint for controlling the engine, characterized in that if a failure of the supply system has been detected, determining a low-pressure compressor flow, limiting the engine control parameter setpoint depending on the low-pressure compressor flow and employing the limited engine control parameter setpoint for controlling the engine.
A method for detecting a steady operating state of a harvester, comprising steps of: electronically sensing a crop parameter (178b, 178c, 178e, 178f, 178g) in the harvester; electronically sensing a processing result parameter (172a, 172b, 174, 178a, 178d) of a result of crop processing in the harvester; electronically transmitting the crop parameter, the processing result parameter, a time derivative of the crop parameter and a time derivative of the processing result parameter as input signals to a fuzzy logic circuit; characterized by electronically generating, by the fuzzy logic circuit, a steady state signal value that is binary and is based upon the input signals, wherein the steady state signal value indicates a steady state of the crop processing in the harvester. electronically sensing a crop parameter (178b, 178c, 178e, 178f, 178g) in the harvester; electronically sensing a processing result parameter (172a, 172b, 174, 178a, 178d) of a result of crop processing in the harvester; electronically transmitting the crop parameter, the processing result parameter, a time derivative of the crop parameter and a time derivative of the processing result parameter as input signals to a fuzzy logic circuit; characterized by electronically generating, by the fuzzy logic circuit, a steady state signal value that is binary and is based upon the input signals, wherein the steady state signal value indicates a steady state of the crop processing in the harvester.
A rotor blade comprising: a first section configured to mount to a rotor hub; a second section being rotatably coupled to the first section and configured to rotate between an aligned position and a folded position, the first section and the second section having a complementary rotor blade airfoil contour; a pin comprising: a cylindrical body configured to couple the first section and the second section of the rotor blade, when the rotor blade is in the aligned position; and a handle mounted to an end of the cylindrical body and having an airfoil contour complementary to the rotor blade airfoil contour, the handle being movable between an open position and a closed position, wherein when the handle is in the closed position, the handle is flush with an adjacent portion of the rotor blade, and when the handle is in the open position, the handle is accessible to pull the cylindrical body from the first and second sections (30, 50) of the rotor blade. a first section configured to mount to a rotor hub; a second section being rotatably coupled to the first section and configured to rotate between an aligned position and a folded position, the first section and the second section having a complementary rotor blade airfoil contour; a pin comprising: a cylindrical body configured to couple the first section and the second section of the rotor blade, when the rotor blade is in the aligned position; and a handle mounted to an end of the cylindrical body and having an airfoil contour complementary to the rotor blade airfoil contour, the handle being movable between an open position and a closed position, wherein when the handle is in the closed position, the handle is flush with an adjacent portion of the rotor blade, and when the handle is in the open position, the handle is accessible to pull the cylindrical body from the first and second sections (30, 50) of the rotor blade. a cylindrical body configured to couple the first section and the second section of the rotor blade, when the rotor blade is in the aligned position; and a handle mounted to an end of the cylindrical body and having an airfoil contour complementary to the rotor blade airfoil contour, the handle being movable between an open position and a closed position, wherein when the handle is in the closed position, the handle is flush with an adjacent portion of the rotor blade, and when the handle is in the open position, the handle is accessible to pull the cylindrical body from the first and second sections (30, 50) of the rotor blade.
Method of managing electricity providing in a computers cluster, comprising: > a process of prediction of need of electricity provided by at least one renewable electricity source (1, 2, 3) in said computers cluster, > a process of prediction of availability of said electricity provided by said renewable electricity source (1, 2, 3), including: ∘ a step of managing failure risk of said renewable electricity source (1, 2, 3), by lowering said predicted availability, so as to: ▪ increase life expectancy of said renewable electricity source (1, 2, 3), ▪ and/or lower maintenance frequency of said renewable electricity source (1, 2, 3), ➢ a process of scheduling tasks in said computers cluster, based on both said prediction processes (6, 8), ➢ said computers cluster comprising more than 1000 terminal nodes, ➢ said process of dynamical reconfiguration of said renewable electricity source (1, 2, 3) using a smart grid components manager, ➢ said process of scheduling tasks in said computers cluster using a workload scheduler holding a queue of pending jobs and mixing all predictions to schedule job executions in computers cluster and to trigger said renewable electricity source (1, 2, 3) reconfiguration by said smart grid components manager. > a process of prediction of need of electricity provided by at least one renewable electricity source (1, 2, 3) in said computers cluster, > a process of prediction of availability of said electricity provided by said renewable electricity source (1, 2, 3), including: ∘ a step of managing failure risk of said renewable electricity source (1, 2, 3), by lowering said predicted availability, so as to: ▪ increase life expectancy of said renewable electricity source (1, 2, 3), ▪ and/or lower maintenance frequency of said renewable electricity source (1, 2, 3), ∘ a step of managing failure risk of said renewable electricity source (1, 2, 3), by lowering said predicted availability, so as to: ▪ increase life expectancy of said renewable electricity source (1, 2, 3), ▪ and/or lower maintenance frequency of said renewable electricity source (1, 2, 3), ▪ increase life expectancy of said renewable electricity source (1, 2, 3), ▪ and/or lower maintenance frequency of said renewable electricity source (1, 2, 3), ➢ a process of scheduling tasks in said computers cluster, based on both said prediction processes (6, 8), ➢ said computers cluster comprising more than 1000 terminal nodes, ➢ said process of dynamical reconfiguration of said renewable electricity source (1, 2, 3) using a smart grid components manager, ➢ said process of scheduling tasks in said computers cluster using a workload scheduler holding a queue of pending jobs and mixing all predictions to schedule job executions in computers cluster and to trigger said renewable electricity source (1, 2, 3) reconfiguration by said smart grid components manager.
A lithium-ion battery (100, 1300) comprising: electrodes comprising an anode and a cathode (110, 120, 1301, 1302); a membrane; an electrolyte; and charge collectors (111, 121), characterized in that the battery further comprises a first material configured and arranged to increase an internal impedance of the battery upon mechanical loading before or shortly after thermal runaway has begun to reduce or eliminate thermal runaway, wherein the first material is a crack or void initiator embedded in the cathode, an amount of the crack or void initiator configured to create cracks or voids in the cathode upon mechanical loading and wherein the crack or void initiator creates cracks or voids in the cathode by debonding of interfaces between the crack or void initiator and the cathode, fracture and rupture of the crack or void initiator, stress concentration caused by the crack or void initiator, and/or local shear, bending, torsion, compression and tension caused by stiffness mismatch of the crack or void initiator and the cathode further characterized in that the first material comprises hollow microfibers. electrodes comprising an anode and a cathode (110, 120, 1301, 1302); a membrane; an electrolyte; and charge collectors (111, 121), characterized in that the battery further comprises a first material configured and arranged to increase an internal impedance of the battery upon mechanical loading before or shortly after thermal runaway has begun to reduce or eliminate thermal runaway, wherein the first material is a crack or void initiator embedded in the cathode, an amount of the crack or void initiator configured to create cracks or voids in the cathode upon mechanical loading and wherein the crack or void initiator creates cracks or voids in the cathode by debonding of interfaces between the crack or void initiator and the cathode, fracture and rupture of the crack or void initiator, stress concentration caused by the crack or void initiator, and/or local shear, bending, torsion, compression and tension caused by stiffness mismatch of the crack or void initiator and the cathode further characterized in that the first material comprises hollow microfibers.
Method for monitoring an alarm path between a radio device and an alarm server for alarm path monitoring, the radio device having a subscriber identification module, SIM-card, and the radio device being adapted to handle an alarm signal from an alarm unit (18,24) and transmit the alarm signal or an alarm message corresponding to the alarm signal over the alarm path that comprises wireless transmission over a communication connection or communication link in a system for data and telecommunication, characterised by a step of running a computer program means for monitoring an alarm path between a radio device and an alarm server, the computer program means is stored on the subscriber identification module as a computer program code that is readable by a digital processing unit of the radio device, the computer program means includes coded instructions making it possible for the radio device by means of the digital processing unit performing a step of communicating open path verifications to the alarm server at predetermined time intervals.
An improved process for the preparation of trifloxystrobin of formula, comprising the steps of: a) preparing a 2-methyl benzene diazonium chloride of formula by reacting 1-amino-2-methylbenzeneof formula with alkali metal nitrite in presence of an acid; b) obtaining a 2-methoxyimino-acetic acid of formula by reacting 2-oxoacetic acid of formula with methoxylamine hydrochloride in presence of a base in a solvent or mixture of solvents; c) obtaining -2-methoxyimino-2-( o -tolyl)acetic acid of formula by reacting a compound of formula with a compound of formula in presence of salt of an acid or a base and a metal sulphate in a suitable solvent or mixture of solvents; d) obtaining -2-methoxyimino-2-( o -tolyl) acetic acid methyl ester formula by reacting a compound of formula with an acid and methanol with or without a solvent or mixture of solvents; e) obtaining an intermediate of formula by reacting a compound formula with metal halogenate in presence of a base with or without catalyst in a solvent or mixture of solvents; Where X = Cl, Br, I f) obtaining trifloxystrobin formula by reacting a compound of formula with a 1-(3-trifluoromethyl-phenyl)-ethanone oxime formula in presence of a base and with or without phase transfer catalyst in a solvent or mixture of solvents. a) preparing a 2-methyl benzene diazonium chloride of formula by reacting 1-amino-2-methylbenzeneof formula with alkali metal nitrite in presence of an acid; b) obtaining a 2-methoxyimino-acetic acid of formula by reacting 2-oxoacetic acid of formula with methoxylamine hydrochloride in presence of a base in a solvent or mixture of solvents; c) obtaining -2-methoxyimino-2-( o -tolyl)acetic acid of formula by reacting a compound of formula with a compound of formula in presence of salt of an acid or a base and a metal sulphate in a suitable solvent or mixture of solvents; d) obtaining -2-methoxyimino-2-( o -tolyl) acetic acid methyl ester formula by reacting a compound of formula with an acid and methanol with or without a solvent or mixture of solvents; e) obtaining an intermediate of formula by reacting a compound formula with metal halogenate in presence of a base with or without catalyst in a solvent or mixture of solvents; Where X = Cl, Br, I f) obtaining trifloxystrobin formula by reacting a compound of formula with a 1-(3-trifluoromethyl-phenyl)-ethanone oxime formula in presence of a base and with or without phase transfer catalyst in a solvent or mixture of solvents.
A system for intercepting and collecting bodies conveyed by a flow of a fluid, comprising: - a pipe portion comprising an inner face that defines an axial inner passage for the flow of the fluid, - at least one filtering element comprising a filtering surface including a first upstream face and a second opposite downstream face, the filtering surface extending transversely in the inner passage so as to intercept, by its first upstream face, bodies conveyed by the flow, - a cleaning device that is arranged across from the first upstream face of the filtering surface and that is able to mechanically sweep said first upstream face, characterized in that several collection openings (26a, 26b) are cleared between the filtering surface and the inner face of the pipe portion and the cleaning device and said at least one filtering element being in alternating relative back and forth motion with respect to one another such that each zone of the first upstream face of the filtering surface is swept mechanically by the cleaning device during each alternating relative back and forth movement in order to orient the bodies intercepted by the first upstream face from the filtering surface toward the collection openings for said bodies. - a pipe portion comprising an inner face that defines an axial inner passage for the flow of the fluid, - at least one filtering element comprising a filtering surface including a first upstream face and a second opposite downstream face, the filtering surface extending transversely in the inner passage so as to intercept, by its first upstream face, bodies conveyed by the flow, - a cleaning device that is arranged across from the first upstream face of the filtering surface and that is able to mechanically sweep said first upstream face, characterized in that several collection openings (26a, 26b) are cleared between the filtering surface and the inner face of the pipe portion and the cleaning device and said at least one filtering element being in alternating relative back and forth motion with respect to one another such that each zone of the first upstream face of the filtering surface is swept mechanically by the cleaning device during each alternating relative back and forth movement in order to orient the bodies intercepted by the first upstream face from the filtering surface toward the collection openings for said bodies.