mhurhangee/ep-ind-claims huggingface dataset:
A pump type dispenser comprising: a pump held by a mouth portion of a container and configured to suction and pressure-feed a content liquid in the container; and a nozzle head having an internal passage through which the pressure-fed content liquid passes and driving the pump by being repeatedly pushed down and restored, wherein the internal passage includes a vertical passage communicating with the pump and a lateral passage connected to the vertical passage and that opens toward the outside, a dispensing member is disposed in the lateral passage, extends from the opening of the internal passage toward a joining portion, and is configured to dispense the content liquid, which is introduced from an inlet on the joining portion side, from an outlet on the opening of the internal passage side, the vertical passage and the lateral passage are connected_in the joining portion, and the nozzle head includes a top wall serving as a pressing portion for pushing down the nozzle head, characterized in that a protrusion protruding from the top wall toward the internal passage is provided in the joining portion, and the dispensing member includes a recessed portion which engages with the protrusion to prevent separation from the lateral passage. a pump held by a mouth portion of a container and configured to suction and pressure-feed a content liquid in the container; and a nozzle head having an internal passage through which the pressure-fed content liquid passes and driving the pump by being repeatedly pushed down and restored, wherein the internal passage includes a vertical passage communicating with the pump and a lateral passage connected to the vertical passage and that opens toward the outside, a dispensing member is disposed in the lateral passage, extends from the opening of the internal passage toward a joining portion, and is configured to dispense the content liquid, which is introduced from an inlet on the joining portion side, from an outlet on the opening of the internal passage side, the vertical passage and the lateral passage are connected_in the joining portion, and the nozzle head includes a top wall serving as a pressing portion for pushing down the nozzle head, characterized in that a protrusion protruding from the top wall toward the internal passage is provided in the joining portion, and the dispensing member includes a recessed portion which engages with the protrusion to prevent separation from the lateral passage.
A method of making an antibody or other Fc containing protein having reduced fucosylation, comprising culturing a host cell in a culture medium comprising 5-Thio-L-fucose and/or a 5-Thio-L-fucose derivative selected from partially or fully acetylated 5-Thio-L-fucose, non-, partially or fully acetylated forms of 2-F-5-Thio-L-Fucose, 5-alkynyl-5-thio-L-fucose, 6, 6, 6-Trifluoro-5-thio-L-fucose and 5-Thio-L-Fucose phosphonate, wherein the host cell expresses the antibody or other Fc containing protein having a Fc domain having at least one N-glycoside- linked sugar chain bound to the Fc domain through an N-acetylglucosamine of the reducing terminal of the sugar chain, and isolating the antibody or other Fc containing protein from the cells, wherein the antibody or other Fc containing protein has reduced fucosylation at the sugar chain compared to the antibody or other Fc containing protein from the same host cell cultured under the otherwise same culturing conditions but in the absence of 5-Thio-L-fucose and/or a derivative thereof.
A process for hydrocracking an oil feed comprising at least 10% by volume of compounds boiling above 340°C, comprising a hydrocracking step, optionally followed by a separation of the gases from the hydrocracked effluent, then a step for fractionation of said effluent, which separates at least one distillate and a residue,, said fractionation step comprising a distillation in a column provided with plates, in which column: • said at least partially vaporized effluent is supplied to the column over at least one supply plate, • said distillate is withdrawn from the level of a withdrawal plate, • said residue is evacuated at an evacuation point, • and, a stripping gas is injected at an injection point located below the supply plate, in which process • a portion of the stream present at the level of at least one plate which is the supply plate or a plate located, between the supply plate and said stripping gas injection point is withdrawn from the column, • all or a portion of said withdrawn stream is recycled to the hydrocracking step, • and the residue is purged in its entirety, in which a portion of the stream present at the level of at least one plate located between the supply plate and the withdrawal plate for the heaviest distillate is withdrawn from the column, said at least one plate being located above said supply plate, in which all or a portion, preferably all, of said stream withdrawn from said plate is stripped in an external stripping step by a stripping gas, and all or a portion, preferably all, of the separated gaseous effluent is recycled to the column above the plate from which said stream has been withdrawn, and all or a portion, preferably all, of the separated liquid effluent is recycled to the hydrocracking step. • said at least partially vaporized effluent is supplied to the column over at least one supply plate, • said distillate is withdrawn from the level of a withdrawal plate, • said residue is evacuated at an evacuation point, • and, a stripping gas is injected at an injection point located below the supply plate, in which process • a portion of the stream present at the level of at least one plate which is the supply plate or a plate located, between the supply plate and said stripping gas injection point is withdrawn from the column, • all or a portion of said withdrawn stream is recycled to the hydrocracking step, • and the residue is purged in its entirety,
A network element (220, 605) for supporting multimedia broadcast multicast communication over a communication system that comprises a broadcast multicast media server, the network element comprising: at least one first radio network control entity (620, 622, 624) dedicated to handle control plane traffic and logic (330, 615) for allocating broadcast control plane traffic to the at least one first radio network control entity (620, 622, 624); at least one second radio network control entity (630, 632) dedicated to handle data plane traffic and logic (330, 615) for allocating broadcast data plane traffic to the at least one second radio network control entity (630, 632); and logic (335, 610) for using a point-to-point protocol for transport of control signalling to a number of wireless base stations operably coupled to the at least one first radio network control entity (620, 622, 624) dedicated to handle control plane traffic. at least one first radio network control entity (620, 622, 624) dedicated to handle control plane traffic and logic (330, 615) for allocating broadcast control plane traffic to the at least one first radio network control entity (620, 622, 624); at least one second radio network control entity (630, 632) dedicated to handle data plane traffic and logic (330, 615) for allocating broadcast data plane traffic to the at least one second radio network control entity (630, 632); and logic (335, 610) for using a point-to-point protocol for transport of control signalling to a number of wireless base stations operably coupled to the at least one first radio network control entity (620, 622, 624) dedicated to handle control plane traffic.
A method of carrying out transmission Raman spectroscopy on a sample comprising: moving a light profile on a sample; collecting Raman scattered light transmitted through the sample that has been generated by interaction of the light profile with the sample at different locations on the sample and directing the Raman light onto at least one photodetector element of a photodetector such that the photodetector element receives the Raman scattered light and accumulates data representative of a summation of the Raman scattered light for a volume of the sample that is greater than the static acquisition collection volume moving a light profile on a sample; collecting Raman scattered light transmitted through the sample that has been generated by interaction of the light profile with the sample at different locations on the sample and directing the Raman light onto at least one photodetector element of a photodetector such that the photodetector element receives the Raman scattered light and accumulates data representative of a summation of the Raman scattered light for a volume of the sample that is greater than the static acquisition collection volume
Light source device having at least one LED with a light emission side and a rear side opposite the light emission side, the at least one LED being arranged on a circuit board, an arrangement plane of the at least one LED being defined by the circuit board; characterized by at least one main heat sink, which is coupled to the rear side of the at least one LED, wherein the main heat sink has an outer surface and has the shape of an irregularly shaped truncated pyramid; wherein the outer surface of the main heat sink has at least a first, a second and a third partial surface, wherein the first partial surface extends parallel to the arrangement plane, wherein the second partial surface encloses a first angle with respect to the first partial surface and the third partial surface encloses a second angle with respect to the first partial surface, wherein the two angles are different and the second partial surface is formed as a first standing surface and the third partial surface as a second standing surface.
A process for production of a titanium slab for hot rolling, using an electron beam melting furnace, in which a rectangular mold is equipped, and pouring molten metal from the top of shorter side wall of the mold.
Laser ignition device for an internal combustion engine, comprising an ignition laser with a combustion chamber window and a protective layer for protecting the combustion chamber window, characterized in that the protective layer burns when the laser ignition device is put into operation.
Process for lowering the sea level because of the sea level rise caused by global warming wherein water is stored permanently in the form of frozen water, especially in the form of ice or snow, in a storage place, wherein the storage place of the water to store permanently in the form of frozen water is located in polar regions, wherein the water to store permanently in the form of frozen water is coming from an ocean or a sea or from a glacier flowing into an ocean or a sea, characterised in that the storage place of the water to store permanently in the form of frozen water is on the ground.
A communication apparatus configured to operate as an access point, the communication apparatus comprising: a communication unit configured to transmit or receive a signal; an information obtaining unit configured to obtain information relating to interference that each transmission destination candidate receives from an interference source; and a controller configured to select each of the transmission destination candidates on a basis of the information when an interference signal arrives;" wherein the information obtaining unit is configured to obtain the information relating to an intensity of a received signal from the interference source of each of the transmission destination candidates; the controller is configured to select each of the transmission destination candidates on a basis of the intensity of the received signal from the interference source that corresponds to the interference signal; the information obtaining unit is configured to obtain the information relating to the intensity of the received signal of an OBSS signal in each terminal station serving as each of the transmission destination candidates in a local BSS, and to obtain, from each of the terminal stations, the information including the BSS identification information that indicates at least one of an OBSS having a maximum intensity of the received signal or an OBSS having a minimum intensity of the received signal; and the controller is configured to manage the information of each of the terminal stations in association with BSS identification information of an OBSS. a communication unit configured to transmit or receive a signal; an information obtaining unit configured to obtain information relating to interference that each transmission destination candidate receives from an interference source; and a controller configured to select each of the transmission destination candidates on a basis of the information when an interference signal arrives;" wherein the information obtaining unit is configured to obtain the information relating to an intensity of a received signal from the interference source of each of the transmission destination candidates; the controller is configured to select each of the transmission destination candidates on a basis of the intensity of the received signal from the interference source that corresponds to the interference signal; the information obtaining unit is configured to obtain the information relating to the intensity of the received signal of an OBSS signal in each terminal station serving as each of the transmission destination candidates in a local BSS, and to obtain, from each of the terminal stations, the information including the BSS identification information that indicates at least one of an OBSS having a maximum intensity of the received signal or an OBSS having a minimum intensity of the received signal; and the controller is configured to manage the information of each of the terminal stations in association with BSS identification information of an OBSS.
A method for preparing alpha sources of polonium, comprising: providing a sample of polonium in a solution; introducing a controlled amount of sulfide and a controlled amount of copper for forming an insoluble sulfide salt in the solution, in order to co-precipitate polonium from the solution; and filtering out the precipitates. providing a sample of polonium in a solution; introducing a controlled amount of sulfide and a controlled amount of copper for forming an insoluble sulfide salt in the solution, in order to co-precipitate polonium from the solution; and filtering out the precipitates.
A foamable otic pharmaceutical composition comprising: (a) an oil-in-water emulsion comprising: (i) an antibiotic agent in an amount effective for antibacterial action; (ii) water in an amount of at least 75 % (w/w) of the total weight of the emulsion; (iii) mineral oil in an amount of no more than 15 % (w/w) of the total weight of the emulsion; (iv) a synthetic surfactant pharmaceutically acceptable for otic use; (v) a foaming agent selected from a fatty alcohol and a fatty acid; (vi) white petrolatum; and (b) a compressed propellant gas; wherein the oil-in-water emulsion is devoid of organic polar co-solvents, the organic polar co-solvents being polyols selected from the group consisting of glycerol, propylene glycol, hexylene glycol, diethylene glycol, and propylene glycol n-alkanols, the oil-in-water emulsion has an osmolarity of about 280 mOsm/L to about 320 mOsm/L, and wherein the composition, packaged in a container, is adapted to form a foam after dispensing from the container. (a) an oil-in-water emulsion comprising: (i) an antibiotic agent in an amount effective for antibacterial action; (ii) water in an amount of at least 75 % (w/w) of the total weight of the emulsion; (iii) mineral oil in an amount of no more than 15 % (w/w) of the total weight of the emulsion; (iv) a synthetic surfactant pharmaceutically acceptable for otic use; (v) a foaming agent selected from a fatty alcohol and a fatty acid; (vi) white petrolatum; and (i) an antibiotic agent in an amount effective for antibacterial action; (ii) water in an amount of at least 75 % (w/w) of the total weight of the emulsion; (iii) mineral oil in an amount of no more than 15 % (w/w) of the total weight of the emulsion; (iv) a synthetic surfactant pharmaceutically acceptable for otic use; (v) a foaming agent selected from a fatty alcohol and a fatty acid; (vi) white petrolatum; and (b) a compressed propellant gas;
A pneumatic barrier, comprising a housing, in which there is arranged a tubular sleeve as well as means connected to the tubular sleeve for delivering and discharging compressed air into / from the tubular sleeve, wherein the tubular sleeve has along the essentially entire length thereof at least one spring element, which maintains the tubular sleeve in a wound-up basic condition of the tubular sleeve, wherein by applying compressed air by the means for delivering and discharging compressed air onto the tubular sleeve in opposition to the spring force of the at least one spring element the tubular sleeve is brought from the wound-up basic condition of the tubular sleeve into an unwound operational condition of the tubular sleeve and wherein while bringing the tubular sleeve from its unwound operational condition into its wound-up basic condition by the spring force of the at least one spring element, the compressed air contained in the tubular sleeve escapes via the means for delivering and discharging compressed air, characterized in that the tubular sleeve has for the horizontal orientation of the tubular sleeve in its unwound operational condition along essentially the entire length thereof a support element having a plurality of chain-like elements connected to one another, in particular a cable drag chain.
An oxidative treatment agent for keratin fibers, in particular for human hair, comprising: a) at least one dicarboxylic acid having 2 to 10 carbon atoms and/or at least one salt of this acid/these acids, b) at least one amino acid, c) hydrogen peroxide, preferably in an amount of 0.5 to 13 wt.%, more preferably 1 to 7 wt.%, particularly preferably 2 to 6 wt.%, and especially particularly preferably 3 to 4.5 wt.% (calculated as 100% H 2 O 2), in each case based on the total weight of the oxidative treatment agent according to the invention, and d) water, preferably in an amount of 20 to 95 wt.%, preferably 30 to 90 wt.%, particularly preferably 40 to 85 wt.%, and exceptionally preferably 50 to 80 wt.%, in each case based on the total weight of the oxidative treatment agent according to the invention, wherein the oxidative treatment agent has a pH value in the range of 2.5 to 6.5, preferably in the range of 3 to 5.5, and particularly preferably in the range of 3.5 to 5.0, each measured at 20°C. a) at least one dicarboxylic acid having 2 to 10 carbon atoms and/or at least one salt of this acid/these acids, b) at least one amino acid, c) hydrogen peroxide, preferably in an amount of 0.5 to 13 wt.%, more preferably 1 to 7 wt.%, particularly preferably 2 to 6 wt.%, and especially particularly preferably 3 to 4.5 wt.% (calculated as 100% H 2 O 2), in each case based on the total weight of the oxidative treatment agent according to the invention, and d) water, preferably in an amount of 20 to 95 wt.%, preferably 30 to 90 wt.%, particularly preferably 40 to 85 wt.%, and exceptionally preferably 50 to 80 wt.%, in each case based on the total weight of the oxidative treatment agent according to the invention,
A method for determining an optimized probe panel for multi-color immunophe-notypic analysis and for differentiating populations of particles in a sample using an antibody database module, the method comprising: receiving, via a user interface, user input corresponding to one or more parameters of a probe panel, the one or more parameters including a set of antibodies corresponding to an antigenic expression pattern; determining, via a processor, the optimized probe panel based on the user input, characterised by the determining comprising: running a simulation of probe panels that satisfy the user input including determining a detection limit for each of one or more detection channels based on the antigenic expression pattern; generating the optimized probe panel based on the detection limit; retrieving, via the antibody database module, part information associated with the optimized probe panel; and displaying, via the user interface, the part information. receiving, via a user interface, user input corresponding to one or more parameters of a probe panel, the one or more parameters including a set of antibodies corresponding to an antigenic expression pattern; determining, via a processor, the optimized probe panel based on the user input, characterised by the determining comprising: running a simulation of probe panels that satisfy the user input including determining a detection limit for each of one or more detection channels based on the antigenic expression pattern; generating the optimized probe panel based on the detection limit; retrieving, via the antibody database module, part information associated with the optimized probe panel; and displaying, via the user interface, the part information. running a simulation of probe panels that satisfy the user input including determining a detection limit for each of one or more detection channels based on the antigenic expression pattern; generating the optimized probe panel based on the detection limit; retrieving, via the antibody database module, part information associated with the optimized probe panel; and displaying, via the user interface, the part information.
A method of increasing the sensitivity of cell-based detection of a botulinum toxin, comprising: (i) providing a transfected cell that produces a construct comprising; (a) a first terminus comprising a reporter-containing portion, wherein the reporter-containing portion exhibits a signal; and, (b) a cleavage site that interacts with the botulinum toxin in a manner that produces a cleavage of the reporter-containing portion from a remainder of the construct; (ii) exposing the transfected cell to the botulinum toxin at a toxin exposure temperature of from 38 °C to 41 °C, wherein sensitivity of the transfected cell's response to the Botulinum toxin at the toxin exposure temperature increases at least 2 fold compared to the transfected cell's sensitivity to the botulinum toxin at 37 °C; (iv) obtaining the signal from the reporter-containing portion. (i) providing a transfected cell that produces a construct comprising; (a) a first terminus comprising a reporter-containing portion, wherein the reporter-containing portion exhibits a signal; and, (b) a cleavage site that interacts with the botulinum toxin in a manner that produces a cleavage of the reporter-containing portion from a remainder of the construct; (a) a first terminus comprising a reporter-containing portion, wherein the reporter-containing portion exhibits a signal; and, (b) a cleavage site that interacts with the botulinum toxin in a manner that produces a cleavage of the reporter-containing portion from a remainder of the construct; (ii) exposing the transfected cell to the botulinum toxin at a toxin exposure temperature of from 38 °C to 41 °C, wherein sensitivity of the transfected cell's response to the Botulinum toxin at the toxin exposure temperature increases at least 2 fold compared to the transfected cell's sensitivity to the botulinum toxin at 37 °C; (iv) obtaining the signal from the reporter-containing portion.