A cartridge for use with a blood testing console, the cartridge comprising: a blood sample receiver configured to receive a blood sample to be tested; blood processing and testing paths (130a, 130b, 130c, 130d, 130e), each blood processing and testing path (130a, 130b, 130c, 130d, 130e) configured for receiving a portion of the blood sample and comprising: a blood sample volume measurement chamber (132a, 132b, 132c, 132d, 132e) in fluid communication with the blood sample receiver, the blood sample volume measurement chamber (132a, 132b, 132c, 132d, 132e) having a selected internal volume to contain a predefined volume of the blood sample; a mixing chamber (134a, 134b, 134c, 134d, 134e) in fluid communication with the blood sample volume measurement chamber (132a, 132b, 132c, 132d, 132e) and with a reagent, the mixing chamber (134a, 134b, 134c, 134d, 134e) configured to receive blood of the predefined volume from the blood sample volume measurement chamber (132a, 132b, 132c, 132d, 132e) and mix the received blood with the reagent; and a blood testing chamber (136a, 136b, 136c, 136d, 136e) configured to receive the mixed blood and reagent from the mixing chamber (134a, 134b, 134c, 134d, 134e) for a test to be performed on the mixed blood and reagent within the blood testing chamber (136a, 136b, 136c, 136d, 136e), wherein the blood sample volume measurement chambers (132a, 132b, 132c, 132d, 132e) of the blood processing and testing paths (130a, 130b, 130c, 130d, 130e) are arranged in a series such that a first blood sample volume measurement chamber is configured to be filled with the blood sample to a predefined level, and thereafter each successive blood sample volume measurement chamber (132b, 132c, 132d, 132e) is configured to be filled in series. a blood sample receiver configured to receive a blood sample to be tested; blood processing and testing paths (130a, 130b, 130c, 130d, 130e), each blood processing and testing path (130a, 130b, 130c, 130d, 130e) configured for receiving a portion of the blood sample and comprising: a blood sample volume measurement chamber (132a, 132b, 132c, 132d, 132e) in fluid communication with the blood sample receiver, the blood sample volume measurement chamber (132a, 132b, 132c, 132d, 132e) having a selected internal volume to contain a predefined volume of the blood sample; a mixing chamber (134a, 134b, 134c, 134d, 134e) in fluid communication with the blood sample volume measurement chamber (132a, 132b, 132c, 132d, 132e) and with a reagent, the mixing chamber (134a, 134b, 134c, 134d, 134e) configured to receive blood of the predefined volume from the blood sample volume measurement chamber (132a, 132b, 132c, 132d, 132e) and mix the received blood with the reagent; and a blood testing chamber (136a, 136b, 136c, 136d, 136e) configured to receive the mixed blood and reagent from the mixing chamber (134a, 134b, 134c, 134d, 134e) for a test to be performed on the mixed blood and reagent within the blood testing chamber (136a, 136b, 136c, 136d, 136e), wherein the blood sample volume measurement chambers (132a, 132b, 132c, 132d, 132e) of the blood processing and testing paths (130a, 130b, 130c, 130d, 130e) are arranged in a series such that a first blood sample volume measurement chamber is configured to be filled with the blood sample to a predefined level, and thereafter each successive blood sample volume measurement chamber (132b, 132c, 132d, 132e) is configured to be filled in series. a blood sample volume measurement chamber (132a, 132b, 132c, 132d, 132e) in fluid communication with the blood sample receiver, the blood sample volume measurement chamber (132a, 132b, 132c, 132d, 132e) having a selected internal volume to contain a predefined volume of the blood sample; a mixing chamber (134a, 134b, 134c, 134d, 134e) in fluid communication with the blood sample volume measurement chamber (132a, 132b, 132c, 132d, 132e) and with a reagent, the mixing chamber (134a, 134b, 134c, 134d, 134e) configured to receive blood of the predefined volume from the blood sample volume measurement chamber (132a, 132b, 132c, 132d, 132e) and mix the received blood with the reagent; and a blood testing chamber (136a, 136b, 136c, 136d, 136e) configured to receive the mixed blood and reagent from the mixing chamber (134a, 134b, 134c, 134d, 134e) for a test to be performed on the mixed blood and reagent within the blood testing chamber (136a, 136b, 136c, 136d, 136e), wherein the blood sample volume measurement chambers (132a, 132b, 132c, 132d, 132e) of the blood processing and testing paths (130a, 130b, 130c, 130d, 130e) are arranged in a series such that a first blood sample volume measurement chamber is configured to be filled with the blood sample to a predefined level, and thereafter each successive blood sample volume measurement chamber (132b, 132c, 132d, 132e) is configured to be filled in series.