A method for diagnosing of patient's skin regenerative and proliferative potential, comprising: a) cultivating skin fibroblast colonies at conditions which provide formation of discrete colonies applicable for visualization, b) conducting statistically reliable analysis of the derived colonies, said analysis comprising: visualization of the formed colonies and analysis of colony images to obtain a range of parameters which characterize growth and morphological particularities of cell cultures which are subsequently used for the determination of the proliferative and regenerative potentials, c) determining efficacy of colony formation as a parameter that defines regenerative potential of a fibroblast population, and determining percentages of dense and diffuse colonies in cell culture, as a parameter that defines proliferative cell potential, and d) processing the results obtained in (a)-(c) which allows evaluating the regenerative and/or proliferative potential of the patient's skin, wherein efficacy of colony formation is calculated as a ratio of the formed colonies with the number of cells > 20 to the total number of explanted cells, the dense colonies are characterized by mean of optical density ≥ 46 relative units, and the diffuse colonies ≤ 25 relative units, and if efficacy of colony formation is less than 45% for men and 36% for women, low regenerative potential is diagnosed; if efficacy of colony formation is in the range 45-49% for men and 36-45% for women, normal regenerative potential is diagnosed, and if efficacy of colony formation is more than 49% for men and 45% for women, high regenerative potential is diagnosed; if percentage of the dense colonies is less than 44%, and percentage of the diffuse colonies is more than 25% for men, and percentage of the dense colonies is less than 40%, and percentage of the diffuse colonies is more than 40% for women, low proliferative potential is diagnosed, if percentage of the dense colonies is in the range 44-54%, and percentage of the diffuse colonies is in the range 20-25% for men, and percentage of the dense colonies is in the range of 40-50%, percentage of the diffuse colonies is in the range 30-40% for women, normal proliferative potential is diagnosed; if percentage of the dense colonies is more than 54%, and percentage of the diffuse colonies is less than 20% for men, and percentage of the dense colonies is more than 50%, and percentage of the diffuse colonies is less than 30% for women, high proliferative potential is diagnosed. a) cultivating skin fibroblast colonies at conditions which provide formation of discrete colonies applicable for visualization, b) conducting statistically reliable analysis of the derived colonies, said analysis comprising: visualization of the formed colonies and analysis of colony images to obtain a range of parameters which characterize growth and morphological particularities of cell cultures which are subsequently used for the determination of the proliferative and regenerative potentials, c) determining efficacy of colony formation as a parameter that defines regenerative potential of a fibroblast population, and determining percentages of dense and diffuse colonies in cell culture, as a parameter that defines proliferative cell potential, and d) processing the results obtained in (a)-(c) which allows evaluating the regenerative and/or proliferative potential of the patient's skin,