An implantable drug-loaded device, comprising: a zinc-containing matrix and an active drug layer attached to the zinc-containing matrix, wherein in the zinc-containing matrix per unit area, the content of an active drug is p,having the unit of μg•mm -2; the content of zinc corroded from the zinc-containing matrix per unit area in a guaranteed grade acetic acid aqueous solution at 8.3 vol.% within unit time is p, having the unit of μg•mm -2 •min -1, wherein the content of zinc corroded from the zinc-containing matrix per unit area is tested in the guaranteed grade acetic acid aqueous solution at 8.3 vol.% at 25 °C by a method consisting of the following steps: - firstly, eluting the active drug layer of the implantable drug-loaded device to expose the zinc-containing portions or to expose the matrix formed of the pure zinc or the zinc alloy; - after being weighed, placing the device into the guaranteed grade acetic acid aqueous solution at 8.3 vol.% at 25 °C for 20 minutes; - after taking out the device, using a fixed volume of acetic acid solution to fix the volume, and then performing a digestion; - testing the zinc ion concentration in corrosive liquid with atomic absorption spectroscopy; - calculating the content of the zinc in the solution at this time, which is the zinc weight loss of the zinc-containing portions or the matrix formed by the pure zinc or the zinc alloy; - finally, dividing the content by the surface area of the device and the corrosion time to obtain the content p of the zinc corroded from the zinc-containing matrix per unit area in the guaranteed grade acetic acid aqueous solution at 8.3 vol.% within unit time; wherein the ρ and the p satisfy the following relation: 0.1≤15p+ρ≤3.5, where p is greater than or equal to 0.005 and less than or equal to 0.14. a zinc-containing matrix and an active drug layer attached to the zinc-containing matrix, wherein in the zinc-containing matrix per unit area, the content of an active drug is p,having the unit of μg•mm -2; the content of zinc corroded from the zinc-containing matrix per unit area in a guaranteed grade acetic acid aqueous solution at 8.3 vol.% within unit time is p, having the unit of μg•mm -2 •min -1, wherein the content of zinc corroded from the zinc-containing matrix per unit area is tested in the guaranteed grade acetic acid aqueous solution at 8.3 vol.% at 25 °C by a method consisting of the following steps: - firstly, eluting the active drug layer of the implantable drug-loaded device to expose the zinc-containing portions or to expose the matrix formed of the pure zinc or the zinc alloy; - after being weighed, placing the device into the guaranteed grade acetic acid aqueous solution at 8.3 vol.% at 25 °C for 20 minutes; - after taking out the device, using a fixed volume of acetic acid solution to fix the volume, and then performing a digestion; - testing the zinc ion concentration in corrosive liquid with atomic absorption spectroscopy; - calculating the content of the zinc in the solution at this time, which is the zinc weight loss of the zinc-containing portions or the matrix formed by the pure zinc or the zinc alloy; - finally, dividing the content by the surface area of the device and the corrosion time to obtain the content p of the zinc corroded from the zinc-containing matrix per unit area in the guaranteed grade acetic acid aqueous solution at 8.3 vol.% within unit time; - firstly, eluting the active drug layer of the implantable drug-loaded device to expose the zinc-containing portions or to expose the matrix formed of the pure zinc or the zinc alloy; - after being weighed, placing the device into the guaranteed grade acetic acid aqueous solution at 8.3 vol.% at 25 °C for 20 minutes; - after taking out the device, using a fixed volume of acetic acid solution to fix the volume, and then performing a digestion; - testing the zinc ion concentration in corrosive liquid with atomic absorption spectroscopy; - calculating the content of the zinc in the solution at this time, which is the zinc weight loss of the zinc-containing portions or the matrix formed by the pure zinc or the zinc alloy; - finally, dividing the content by the surface area of the device and the corrosion time to obtain the content p of the zinc corroded from the zinc-containing matrix per unit area in the guaranteed grade acetic acid aqueous solution at 8.3 vol.% within unit time; wherein the ρ and the p satisfy the following relation: 0.1≤15p+ρ≤3.5, where p is greater than or equal to 0.005 and less than or equal to 0.14.