mhurhangee/ep-ind-claims huggingface dataset:
A liquid composition containing naked RNA for use in the treatment or prevention of ligament or tendon lesions, wherein the RNA is solved in a glucose solution, and wherein the RNA is mRNA and wherein the polypeptide encoded by the mRNA is selected from the group consisting of platelet-derived growth factor (PDGF), basic fibroblast growth factor (bFGF), insulin-like growth factor 1(IGF-1), transforming growth factor β1 (TGF-β1), epidermal growth factor, a growth and differentiation factor, Vegf and bone morphogenetic protein.
Battery cell, in particular lithium-ion battery cell, comprising a cell housing having a base area on which the battery cell is placed and at least one side face and two terminals, wherein a first terminal is electrically conductively connected to the cathode of the battery cell and a second terminal is electrically conductively connected to the anode of the battery cell, wherein the terminals (20, 30) are arranged on at least one side face of the cell housing, wherein the battery cell has at least one elastically deformable element for realizing an elastically displaceable position of a contact area of a terminal (20, 30), characterized in that the elastically deformable element is a side face (12, 13) on which a terminal (20, 30) is fixedly arranged or which itself forms the terminal.
A method for producing a fitting element or a piping unit comprising the steps of: a) providing a metal insert, b) treating said metal insert in a plasma reactor under vacuum with supply of oxygen gas for modifying and oxidizing the metal surface, c) dipping the metal insert into a fluidized bed and applying adhesive polymer powders onto the surface of said insert, d) overmoulding the metal surface with a plastic material by injection moulding, and forming a fitting element or a piping unit, wherein; after step b), the metal insert is heated up to a temperature above the melting point of the adhesive polymer, the heating being carried out prior or after the powder coating in the fluidized bed, whereby said adhesive polymer being selected from maleic anhydride grafted polyolefins. a) providing a metal insert, b) treating said metal insert in a plasma reactor under vacuum with supply of oxygen gas for modifying and oxidizing the metal surface, c) dipping the metal insert into a fluidized bed and applying adhesive polymer powders onto the surface of said insert, d) overmoulding the metal surface with a plastic material by injection moulding, and forming a fitting element or a piping unit,
A method for producing a gel particle, comprising performing radical polymerization reaction involving the cationic polymerization initiator having a chemical structure represented by General formula: [wherein Y represents a single bond or CR 85, Z represents a single bond or CR 86, R 72, R 73, R 75, R 76, R 77, R 78, R 85 and R 86 are each independently selected from the group consisting of hydrogen atom, C 1-6 alkyl group, C 1-6 alkoxy group, C 1-6 alkylcarbonyl group, phenyl group and hydroxyl group, wherein said C 1-6 alkyl group, C 1-6 alkoxy group, C 1-6 alkylcarbonyl group and phenyl group are optionally substituted with 1 or 2 substituents selected from the group consisting of C 1-6 alkyl group, C 1-6 alkoxy group, C 1-6 alkylcarbonyl group, phenyl group and hydroxyl group, R 72 and R 73 optionally each independently represent adamanthyl group or C 1-6 alkyl group substituted with Si(OCH 3) 2 (CH 3), or R 75 and R 76 or R 77 and R 78 together optionally form -(CH 2) 3-5 -, R 81, R 82, R 83 and R 84 are a substituent selected from the group consisting of C 1-4 alkyl group, C 1-4 alkylcarbonyl group and C 1-3 alkoxy group, wherein the C 1-4 alkyl is optionally substituted with one C 1-3 alkoxy group; and R 71 and R 74 each independently are C 1-3 alkyl group, and X f - is counter anion.], and a monomer comprising carbon-carbon double bonds, and a crosslinker. Y represents a single bond or CR 85, Z represents a single bond or CR 86, R 72, R 73, R 75, R 76, R 77, R 78, R 85 and R 86 are each independently selected from the group consisting of hydrogen atom, C 1-6 alkyl group, C 1-6 alkoxy group, C 1-6 alkylcarbonyl group, phenyl group and hydroxyl group, wherein said C 1-6 alkyl group, C 1-6 alkoxy group, C 1-6 alkylcarbonyl group and phenyl group are optionally substituted with 1 or 2 substituents selected from the group consisting of C 1-6 alkyl group, C 1-6 alkoxy group, C 1-6 alkylcarbonyl group, phenyl group and hydroxyl group, R 72 and R 73 optionally each independently represent adamanthyl group or C 1-6 alkyl group substituted with Si(OCH 3) 2 (CH 3), or R 75 and R 76 or R 77 and R 78 together optionally form -(CH 2) 3-5 -, R 81, R 82, R 83 and R 84 are a substituent selected from the group consisting of C 1-4 alkyl group, C 1-4 alkylcarbonyl group and C 1-3 alkoxy group, wherein the C 1-4 alkyl is optionally substituted with one C 1-3 alkoxy group; and R 71 and R 74 each independently are C 1-3 alkyl group, and X f - is counter anion.],
Sensor device for measuring a displacement position of an optical component, having 1.1 a plurality of stator electrodes (44 i; 47, 48), which each have a plurality of individual electrodes that are arranged in a ring-shaped region and that each extend in a plane through a central axis of this region, 1.2 at least one movable electrode, which leads to variable shielding of an electric field in the region of the stator electrodes (44 i; 47, 48) depending on the displacement position of the optical component, and 1.3 at least one means for restricting the electric field that is relevant to the measurement of the displacement position of the optical component to the region of the stator electrodes (44 i; 47, 48), 1.4 wherein the means for restricting the electric field that is relevant to the measurement of the displacement position of the optical component to the region of the stator electrodes (44 i; 47, 48) comprises shielding electrodes (62, 62'), 1.5 wherein the shielding electrodes (62, 62') are each arranged along a continuation of one of the stator electrodes (44 i; 47, 48), and 1.6 wherein the shielding electrodes (62, 62') are separated from the stator electrodes (44 i; 47, 48) by a gap. 1.1 a plurality of stator electrodes (44 i; 47, 48), which each have a plurality of individual electrodes that are arranged in a ring-shaped region and that each extend in a plane through a central axis of this region, 1.2 at least one movable electrode, which leads to variable shielding of an electric field in the region of the stator electrodes (44 i; 47, 48) depending on the displacement position of the optical component, and 1.3 at least one means for restricting the electric field that is relevant to the measurement of the displacement position of the optical component to the region of the stator electrodes (44 i; 47, 48), 1.4 wherein the means for restricting the electric field that is relevant to the measurement of the displacement position of the optical component to the region of the stator electrodes (44 i; 47, 48) comprises shielding electrodes (62, 62'), 1.5 wherein the shielding electrodes (62, 62') are each arranged along a continuation of one of the stator electrodes (44 i; 47, 48), and 1.6 wherein the shielding electrodes (62, 62') are separated from the stator electrodes (44 i; 47, 48) by a gap.
A mechanical bypass switch device arranged to be directly connected between the terminals of a first converter cell to bypass the first converter cell in a power converter, the mechanical switch device comprising: a mechanical switch; a mechanical switch actuator arranged to make the mechanical switch conduct when supplied with an electric signal; a first control input; and a second control input; wherein the mechanical bypass switch device is arranged such that a control signal, provided on either one of the first control input and the second control input or on both of the first control input and the second control input, causes the mechanical switch to conduct and such that the first control input is to be connected with a local control unit of the first converter cell and the second control input is to be connected with a local control unit of a second converter cell. a mechanical switch; a mechanical switch actuator arranged to make the mechanical switch conduct when supplied with an electric signal; a first control input; and a second control input; wherein the mechanical bypass switch device is arranged such that a control signal, provided on either one of the first control input and the second control input or on both of the first control input and the second control input, causes the mechanical switch to conduct and such that the first control input is to be connected with a local control unit of the first converter cell and the second control input is to be connected with a local control unit of a second converter cell.
Compounds of general formula: wherein: J and K are independently of one another hydrogen, a straight or branched C 1 -C 22 acyl or benzoyl group or an acyl group of formula: wherein: F is a C 1 -C 20 alkylene or C 3 -C 10 cycloalkylene group optionally containing one or more unsaturations or an aromatic group, preferably a phenylene or naphthalene ring, M 5 is hydrogen or a straight or branched, saturated or unsaturated C 1 -C 18 alkyl group or an aromatic group, with the proviso that J and K can never both be hydrogen, L is an optionally unsaturated C 1 -C 6 alkylene or isoalkylene group, M 1, M 2, which can be the same or different, are hydrogen or C 1 -C 8 alkyl, M 3, M 4, which can be the same or different, are hydrogen or straight or branched C 1 -C 4 alkyl groups, or an -OG 1 group wherein G 1 is hydrogen or a straight or branched, saturated or unsaturated C 1 -C 10 alkyl group. F is a C 1 -C 20 alkylene or C 3 -C 10 cycloalkylene group optionally containing one or more unsaturations or an aromatic group, preferably a phenylene or naphthalene ring, M 5 is hydrogen or a straight or branched, saturated or unsaturated C 1 -C 18 alkyl group or an aromatic group, with the proviso that J and K can never both be hydrogen, L is an optionally unsaturated C 1 -C 6 alkylene or isoalkylene group, M 1, M 2, which can be the same or different, are hydrogen or C 1 -C 8 alkyl, M 3, M 4, which can be the same or different, are hydrogen or straight or branched C 1 -C 4 alkyl groups, or an -OG 1 group wherein G 1 is hydrogen or a straight or branched, saturated or unsaturated C 1 -C 10 alkyl group.
A friction material that does not include a metal or a metal alloy, characterized in that said friction material includes: a binder being at least a thermosetting resin selected from a phenolic resin and epoxy resin, a resin obtained by modifying said thermosetting resin by cashew oil, silicon oil or various elastomers, and/or a resin obtained by dispersing various elastomers and/or fluorinated polymer in said thermosetting resin; a flat flake shaped titanate with average diameter of 10 to 50 μm as an inorganic filler, the average diameter being measured according to a Laser Diffraction-Type Particle Size Distribution Measuring Method, and a hydrous magnesium silicate as an inorganic filler, wherein an amount of said flat flake shaped titanate and said hydrous magnesium silicate is 20 to 30 volume percent relative to the total amount of the friction material, and wherein the volume ratio of said flat flake shaped titanate and said hydrous magnesium silicate is 12:1 to 5:1. a binder being at least a thermosetting resin selected from a phenolic resin and epoxy resin, a resin obtained by modifying said thermosetting resin by cashew oil, silicon oil or various elastomers, and/or a resin obtained by dispersing various elastomers and/or fluorinated polymer in said thermosetting resin; a flat flake shaped titanate with average diameter of 10 to 50 μm as an inorganic filler, the average diameter being measured according to a Laser Diffraction-Type Particle Size Distribution Measuring Method, and a hydrous magnesium silicate as an inorganic filler, wherein an amount of said flat flake shaped titanate and said hydrous magnesium silicate is 20 to 30 volume percent relative to the total amount of the friction material, and wherein the volume ratio of said flat flake shaped titanate and said hydrous magnesium silicate is 12:1 to 5:1.
A mobile disinfection unit for disinfecting a given facility or equipment, the mobile disinfection unit comprising - at least one first inlet tube arranged for intake of air from the facility or equipment for a treatment step, - at least one second inlet tube arranged for intake of air from the facility or equipment for a removal step, - at least one outlet tube arranged for communicating with either the at least one first or second inlet tube, - a water tank in communication with the at least one outlet tube, - means for producing ozone in communication with the at least one outlet tube, - optionally means for adding negative ions or electrical charge to the air, - at least one sensor for detecting the ozone concentration in the facility or equipment and optionally an additional parameter in the facility or equipment, said additional parameter is selected from the group of temperature, relative humidity, concentration of one or more contaminants, and any combination of said parameters, - means for controlling the operation of the mobile disinfection unit, - said at least one second inlet tube comprises a VOC filter arranged for removing bacterial viruses and other contaminants, - characterized in that said at least one second inlet tube further comprises a catalytic converter device arranged for decomposing ozone and an electrostatic filter arranged for removing molecules, particles, droplets, smoke and dust. - at least one first inlet tube arranged for intake of air from the facility or equipment for a treatment step, - at least one second inlet tube arranged for intake of air from the facility or equipment for a removal step, - at least one outlet tube arranged for communicating with either the at least one first or second inlet tube, - a water tank in communication with the at least one outlet tube, - means for producing ozone in communication with the at least one outlet tube, - optionally means for adding negative ions or electrical charge to the air, - at least one sensor for detecting the ozone concentration in the facility or equipment and optionally an additional parameter in the facility or equipment, said additional parameter is selected from the group of temperature, relative humidity, concentration of one or more contaminants, and any combination of said parameters, - means for controlling the operation of the mobile disinfection unit, - said at least one second inlet tube comprises a VOC filter arranged for removing bacterial viruses and other contaminants, - characterized in that said at least one second inlet tube further comprises a catalytic converter device arranged for decomposing ozone and an electrostatic filter arranged for removing molecules, particles, droplets, smoke and dust.
A gas turbine engine stand comprising: • an engine frame; • a base frame having a slide rail to enable axial translation of the engine frame relative to the base frame; • a load transfer arrangement comprising a first engagement feature to engage with a part of the engine frame and a second engagement feature to slidingly engage with the slide rail; • a locking mechanism to lock the engine frame to the base frame to prevent relative axial translation; and • a load path selection mechanism to select and engage one of the locking mechanism and the load transfer arrangement as the load path between the engine frame and the base frame. • an engine frame; • a base frame having a slide rail to enable axial translation of the engine frame relative to the base frame; • a load transfer arrangement comprising a first engagement feature to engage with a part of the engine frame and a second engagement feature to slidingly engage with the slide rail; • a locking mechanism to lock the engine frame to the base frame to prevent relative axial translation; and • a load path selection mechanism to select and engage one of the locking mechanism and the load transfer arrangement as the load path between the engine frame and the base frame.
One or more agent(s) that increase central dopaminergic neuronal activity selected from bromocriptine, lisuride, hydergine and/or dihydroergotoxine, plus a first-phase insulin secretagouge (FPIS), for use in treating prediabetes, Impaired Fasting Glucose, Impaired Glucose Tolerance or Type 2 Diabetes, wherein the FPIS is glucagon like peptide - 1 (GLP-1) or a GLP-1 receptor agonist wherein said agent is administered to a human to increase central dopaminergic activity primarily within 4 hours of waking in the morning.
A cosmetic method of treating or reducing edematous fibrosclerotic panniculopathy in a patient comprising the steps of: providing a pharmaceutical composition comprising collagenase I and collagenase II in an approximate 1:1 mass ratio and having a specific activity of about 10,000 ABC units per 0.58 mg of collagenase, wherein the collagenase I and collagenase II have a purity of at least about 95% by area as determined by reverse phase high performance liquid chromatography, and administering one or a plurality of concurrent subdermal injections of the pharmaceutical composition to an area affected by EFP, wherein the dose of collagenase I and collagenase II per injection comprises between about 0.00029 mg to about 0.0116 mg and the total dose of the collagenase I and collagenase II administered comprises between about 0.00029 mg and about 0.116 mg, wherein the plurality of subdermal injections are administered at a plurality of injection sites within the area affected by EFP, the area of EFP having a length of about 6 cm to about 15 cm and a width of about 4 cm to about 10 cm.
Geotechnical apparatus equipped for pushing a continuous rod with a probe into the ground without a support and guidance and for pulling the continuous rod with the probe out of the ground for performing a geotechnical investigation using a sounding apparatus for determining a penetration resistance of the ground, the apparatus comprising a holder with the rod wherein the rod is coiled on the holder, and the apparatus comprises a rod bending/ straightening device and a drive unit for both uncoiling the coiled continuous rod during said pushing of the uncoiled rod into the ground and recoiling the uncoiled rod during said pulling of the rod out of the ground, the apparatus being arranged for operation on land as well as on a sea floor, wherein the probe is the sounding apparatus for determining the penetration resistance, and wherein the bending/straightening device is equipped with a first set (8, 9, 10) of rollers of which at least two are positioned at one side of the rod and the remaining rollers form a second set (11, 12) of rollers positioned at an opposing side of the rod, so as to arrange that the rollers (8, 9, 10, 11, 12) are arranged to convert the coiled rod to an essentially straight rod when uncoiling and are arranged to convert the straight rod to a coiled rod of an essentially constant coil diameter when coiling, and wherein the drive unit comprises two grippers (15, 17) arranged to alternatingly grip the rod characterized in that the drive unit further comprises means to move said two grippers along a longitudinal axis of said rod over a predefined length.
A protective hood for use by a firefighter or other emergency worker, the hood comprising: a crown portion to cover the top of a wearer's head; a head portion that extends downward from the crown portion to cover at least the sides and back of the head; and a face opening in the head portion for at least the eyes of a wearer, the face opening defined by a peripheral edge that surrounds the face opening; wherein at least one of the crown portion and all or part of the peripheral edge is formed from at least one layer of knit material, and all or part of the head portion comprises at least one layer of a woven textile; characterized in that part of the peripheral edge is formed from at least one layer of knit material and the remainder of the peripheral edge is formed from at least one layer of woven material. a crown portion to cover the top of a wearer's head; a head portion that extends downward from the crown portion to cover at least the sides and back of the head; and a face opening in the head portion for at least the eyes of a wearer, the face opening defined by a peripheral edge that surrounds the face opening; wherein at least one of the crown portion and all or part of the peripheral edge is formed from at least one layer of knit material, and all or part of the head portion comprises at least one layer of a woven textile; characterized in that part of the peripheral edge is formed from at least one layer of knit material and the remainder of the peripheral edge is formed from at least one layer of woven material.
A compound of formula II: or a pharmaceutically acceptable salt, or ester thereof, wherein: Z is NH or O; R is H or-A-B; A is NR A C, O, S m, C, C O, C NR A, or absent; B is alkyl, alkoxy, or aryl, each of which is optionally substituted with alkyl, alkenyl, alkynyl, haloalkyl, alkoxy, cycloalkyl, heterocycloalkyl, aryl, or hydroxyl, each of which is optionally substituted; R 1 is H, alkyl, alkoxy, or halo; each of which is optionally substituted; R 2 is H, C R A, C OR A, C NR A R B, C(NR B)R A, or C(NR B)OR A; each R A is independently H, alkyl, alkenyl, cycloalkyl, heterocyclic, aryl or heteroaryl, each of which is optionally substituted; each R B is independently H, alkyl, alkenyl, cycloalkyl, heterocyclic, aryl or heteroaryl, each of which is optionally substituted; and m is 0, 1, or 2. Z is NH or O; R is H or-A-B; A is NR A C, O, S m, C, C O, C NR A, or absent; B is alkyl, alkoxy, or aryl, each of which is optionally substituted with alkyl, alkenyl, alkynyl, haloalkyl, alkoxy, cycloalkyl, heterocycloalkyl, aryl, or hydroxyl, each of which is optionally substituted; R 1 is H, alkyl, alkoxy, or halo; each of which is optionally substituted; R 2 is H, C R A, C OR A, C NR A R B, C(NR B)R A, or C(NR B)OR A; each R A is independently H, alkyl, alkenyl, cycloalkyl, heterocyclic, aryl or heteroaryl, each of which is optionally substituted; each R B is independently H, alkyl, alkenyl, cycloalkyl, heterocyclic, aryl or heteroaryl, each of which is optionally substituted; and m is 0, 1, or 2.