A pre-filled drug delivery device having a dose expulsion control mechanism, the prefilled drug delivery device comprising: a syringe body including a proximal end and a distal end; a plunger rod extending into the syringe body through an opening at the proximal end of the syringe body, the plunger rod including a cap and a plunger rod pin arm (824/908) extending distally from the cap separately from the plunger rod body, the plunger rod pin arm (824/908) having a distal end with a pin protruding outward from the plunger rod pin arm (824/908), and a sleeve on the proximal end of the syringe body, the sleeve including an opening for receiving the plunger rod and a channel for receiving the pin of the plunger rod pin arm (824/908), wherein the sleeve includes a first proximal surface and a second proximal surface, wherein the first proximal surface is longitudinally and laterally offset from the second proximal surface, and each of the first proximal surface and the second proximal surface are configured to stop movement of the plunger rod pin arm (824/908) upon abutting against the pin of the plunger rod pin arm (824/908), wherein the plunger rod is configured to transition the pre-filled drug delivery device from an initial configuration to a primed configuration by translating the plunger rod pin arm (824/908) distally relative to the channel until the pin of the plunger rod pin arm (824/908) abuts against the first proximal surface of the sleeve, thereby stopping distal advancement of the plunger rod relative to the sleeve; wherein the plunger rod is configured to transition the pre-filled drug delivery device from the primed configuration to a dosage delivery configuration by rotating the plunger rod relative to the sleeve after the plunger rod transitions the pre-filled drug delivery device from the initial configuration to the primed configuration, wherein rotating the plunger rod causes the pin of the plunger rod pin arm (824/908) previously abutting the first proximal surface of the sleeve to move laterally relative to the sleeve to align longitudinally with the second proximal surface of the sleeve and to no longer abut the first proximal surface, so that further distal translation of the pin of the plunger rod pin arm (824/908) along the channel allows the plunger rod to move distally relative to the sleeve, and wherein, in the dosage delivery configuration, the channel allows distal movement of the pin of the plunger rod pin arm (824/908) until abutting against the second proximal surface to allow the plunger rod to move a dosage delivery distance. a syringe body including a proximal end and a distal end; a plunger rod extending into the syringe body through an opening at the proximal end of the syringe body, the plunger rod including a cap and a plunger rod pin arm (824/908) extending distally from the cap separately from the plunger rod body, the plunger rod pin arm (824/908) having a distal end with a pin protruding outward from the plunger rod pin arm (824/908), and a sleeve on the proximal end of the syringe body, the sleeve including an opening for receiving the plunger rod and a channel for receiving the pin of the plunger rod pin arm (824/908), wherein the sleeve includes a first proximal surface and a second proximal surface, wherein the first proximal surface is longitudinally and laterally offset from the second proximal surface, and each of the first proximal surface and the second proximal surface are configured to stop movement of the plunger rod pin arm (824/908) upon abutting against the pin of the plunger rod pin arm (824/908), wherein the plunger rod is configured to transition the pre-filled drug delivery device from an initial configuration to a primed configuration by translating the plunger rod pin arm (824/908) distally relative to the channel until the pin of the plunger rod pin arm (824/908) abuts against the first proximal surface of the sleeve, thereby stopping distal advancement of the plunger rod relative to the sleeve; wherein the plunger rod is configured to transition the pre-filled drug delivery device from the primed configuration to a dosage delivery configuration by rotating the plunger rod relative to the sleeve after the plunger rod transitions the pre-filled drug delivery device from the initial configuration to the primed configuration, wherein rotating the plunger rod causes the pin of the plunger rod pin arm (824/908) previously abutting the first proximal surface of the sleeve to move laterally relative to the sleeve to align longitudinally with the second proximal surface of the sleeve and to no longer abut the first proximal surface, so that further distal translation of the pin of the plunger rod pin arm (824/908) along the channel allows the plunger rod to move distally relative to the sleeve, and wherein, in the dosage delivery configuration, the channel allows distal movement of the pin of the plunger rod pin arm (824/908) until abutting against the second proximal surface to allow the plunger rod to move a dosage delivery distance.