mhurhangee/ep-ind-claims huggingface dataset:
An expression cassette which comprises a promoter, a polynucleotide sequence encoding a polypeptide, and expression enhancing element wherein expression enhancing element comprises a non-translated genomic DNA sequence downstream of a mammalian Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) promoter, wherein the polypeptide encoded by the polynucleotide sequence is not GAPDH, and wherein the genomic DNA sequence downstream of the mammalian GAPDH promoter starts within a region spanning from nucleotide position around +1 to nucleotide position around +7000, wherein the nucleotide position is relative to the transcription start of the GAPDH mRNA, and wherein the length of the non-translated genomic DNA sequence downstream of the mammalian GAPDH promoter is from around 200 to around 2800 nucleotides and wherein the expression cassette further comprises a non-translated genomic DNA sequence upstream of a mammalian GAPDH promoter, wherein the non-translated genomic DNA sequence upstream of the mammalian GAPDH promoter starts within a region spanning from around the 5' end of the mammalian GAPDH promoter to nucleotide position around -3500, wherein the nucleotide position is relative to the transcription start of the GAPDH mRNA, and wherein the length of the non-translated genomic DNA sequence upstream of the mammalian GAPDH promoter is from around 200 to around 2800 nucleotides.
A system for measuring forces in a space within one side of a knee joint, the system comprising: a hand-held force sensor configured to measure a force or a pressure generated within the knee joint, the hand-held force sensor comprising an elongate housing and a sensor element, characterised in that the force sensor is a unicompartmental force sensor configured to measure a force or a pressure generated in a medial compartment or in a lateral compartment within the knee joint, the elongate housing comprising a thin force sensing distal portion and a thicker proximal handle portion, wherein the thin force sensing distal portion includes the sensor element. a hand-held force sensor configured to measure a force or a pressure generated within the knee joint, the hand-held force sensor comprising an elongate housing and a sensor element, characterised in that the force sensor is a unicompartmental force sensor configured to measure a force or a pressure generated in a medial compartment or in a lateral compartment within the knee joint, the elongate housing comprising a thin force sensing distal portion and a thicker proximal handle portion, wherein the thin force sensing distal portion includes the sensor element.
A stage light having a motor braking system, comprising a controlled component, a braking motor that drives the controlled component to move, and a controller, wherein the braking motor comprises a motor unit and a braking unit for braking the motor unit, and the braking motor is a power-off locking motor, characterized in that the motor unit and the braking unit are electrically connected in parallel with each other and are both electrically connected to the controller, and when detecting that the motor unit is powered on, the controller controls the motor unit to provide a holding torque, and then controls the braking unit to be powered on to release a locked state.
A polysaccharide-protein conjugate comprising a chimeric carrier protein and a polysaccharide antigen, wherein the chimeric carrier protein comprises a carrier protein and a universal epitope, wherein the polysaccharide antigen is covalently conjugated to the chimeric carrier protein, and wherein the chimeric carrier protein comprises the amino acid sequence of any one selected from the group consisting of SEQ ID NOs: 8-32, 39-44, and 51-56.
An air vent for a motor vehicle, comprising a housing which defines an air guiding channel and a plurality of lamellae which are provided at their ends with bearing pins (12, 14), the lamellae being pivotably attached thereby to the housing, wherein the lamellae are mounted on opposing sides with one respective radial bearing (28, 40) and on just one side with one respective axial bearing such that the lamellae are mounted in the housing by a combination of fixed bearings and floating bearings, wherein, the radial bearings (28, 40) are designed as a circular opening (28, 40), the corresponding bearing pin (12, 14) engaging therein; and the radial bearings (28, 40) are attached to the housing so as to be able to be resiliently deflected in the axial direction, and on this just one side the radial bearing opening being formed in a radial bearing strip, which is attached to the housing of the air vent, wherein the radial bearing strip is connected by a connecting portion to the housing of the air vent, and characterised in that, the radial bearing strip protrudes to a side of the housing of the air vent. wherein, the radial bearings (28, 40) are designed as a circular opening (28, 40), the corresponding bearing pin (12, 14) engaging therein; and the radial bearings (28, 40) are attached to the housing so as to be able to be resiliently deflected in the axial direction, and on this just one side the radial bearing opening being formed in a radial bearing strip, which is attached to the housing of the air vent, wherein the radial bearing strip is connected by a connecting portion to the housing of the air vent, and characterised in that, the radial bearing strip protrudes to a side of the housing of the air vent.
Connector assembly for connecting male terminals to female terminals that comprises a connector defining a body and input openings which are communicating with a housing for input male terminals, output openings through which the female terminal wiring is passed, separation walls, a first cover, hinged to the connector and: - a second cover comprising a base and hinged to the said connector,and facing the first cover, and - female terminals made of an electrical conductive material and housed in the housing of connector, which expand when the male terminals are inserted inside them, and wherein the space in the housing is larger than the space occupied by the female terminals prior to expanding, characterized in that said connector further comprises side tabs for positioning the connector and in that the second cover when closed blocks the side tabs. - a second cover comprising a base and hinged to the said connector,and facing the first cover, and - female terminals made of an electrical conductive material and housed in the housing of connector, which expand when the male terminals are inserted inside them, and wherein the space in the housing is larger than the space occupied by the female terminals prior to expanding, characterized in that said connector further comprises side tabs for positioning the connector and in that the second cover when closed blocks the side tabs.
A mounting device for a spaced-apart mounting of a support profile on a roof substructure with a roof hook, which comprises a mounting plate and a setting portion being arranged essentially parallel to the mounting plate and having mounting means for the support profile, wherein the mounting means comprises a mounting screw and a retaining element, which comprises a retaining portion for the support profile as well as a through-opening for the mounting screw, wherein the retaining element comprises a first side and a second side, wherein the second side is situated opposite to the first side and faces the setting portion of the roof hook, characterized in that the retaining element comprises at least one abutment element protruding from the first side of the retaining element for the support profile, whereby the support profile that can be deposited on the setting portion of the roof hook can be hold.
A carrier lifetime measurement method comprising material excitation, and detection of light emitted from that material; further comprising the steps of exciting the material such that excitation periods are repeated at periodic intervals; optically separating, via a detection modulation device, decaying light emitted after an end of the excitation period from light emitted from the material during the excitation period; and supplying a plurality of separated decaying light emissions to a light detecting device whereby the light detecting device detects and accumulates by integration a plurality of the separated decaying light emissions within an integration time which spans a plurality of the excitation periods and obtains a carrier lifetime based on the accumulated intensity.
A method of revealing exposure of a substrate to an environmental stimulus comprising: exposing said substrate to said environmental stimulus; wherein: said substrate comprises at least one indicia, wherein each of said at least one indicia comprises: a plurality of chromatically selective scattering particles having a particle size distribution as measured by (weight average diameter)/(number average diameter) of less than or equal to about 1.1, and a colorant; and said at least one indicia exhibits a change in color in response to said environmental stimulus; wherein the environmental stimulus is pressure. exposing said substrate to said environmental stimulus; wherein: said substrate comprises at least one indicia, wherein each of said at least one indicia comprises: a plurality of chromatically selective scattering particles having a particle size distribution as measured by (weight average diameter)/(number average diameter) of less than or equal to about 1.1, and a colorant; and said at least one indicia exhibits a change in color in response to said environmental stimulus; wherein the environmental stimulus is pressure. said substrate comprises at least one indicia, wherein each of said at least one indicia comprises: a plurality of chromatically selective scattering particles having a particle size distribution as measured by (weight average diameter)/(number average diameter) of less than or equal to about 1.1, and a colorant; and a plurality of chromatically selective scattering particles having a particle size distribution as measured by (weight average diameter)/(number average diameter) of less than or equal to about 1.1, and a colorant; and said at least one indicia exhibits a change in color in response to said environmental stimulus; wherein the environmental stimulus is pressure.
A composite electrolyte film comprising: an ionically conductive substrate; a composite electrolyte layer disposed on a first surface of the ionically conductive substrate, opposite to a second surface; and an electrolyte layer disposed on the second surface of the ionically conductive substrate, wherein the composite electrolyte layer comprises: a first domain comprising a plurality of two-dimensional nanostructures; and a second domain which is disposed in an interstitial space between neighboring two-dimensional nanostructures of the plurality of two-dimensional nanostructures; wherein the second domain comprises a first electrolyte. an ionically conductive substrate; a composite electrolyte layer disposed on a first surface of the ionically conductive substrate, opposite to a second surface; and an electrolyte layer disposed on the second surface of the ionically conductive substrate, wherein the composite electrolyte layer comprises: a first domain comprising a plurality of two-dimensional nanostructures; and a second domain which is disposed in an interstitial space between neighboring two-dimensional nanostructures of the plurality of two-dimensional nanostructures; a first domain comprising a plurality of two-dimensional nanostructures; and a second domain which is disposed in an interstitial space between neighboring two-dimensional nanostructures of the plurality of two-dimensional nanostructures; wherein the second domain comprises a first electrolyte.
An X-ray photographing device comprising: an X-ray irradiating unit configured to irradiate an object with an X-ray beam; an X-ray imaging member having a light-receiving surface configured to receive the X-ray beam transmitted through the object; a pivot drive unit configured to cause the X-ray irradiating unit and the X-ray imaging member to have a pivoting motion around the object in a circumferential direction about a pivoting center line (La); and a control unit configured to control the pivot drive unit; a sub-drive unit, controlled by the control unit, configured to cause a driven member which is at least one of the X-ray irradiating unit and the X-ray imaging member to undergo a local motion which is different from the pivoting motion, the local motion being a rotational motion about a rotation center line (Lc) with an interval between the rotation center line and the driven member, and the local motion resulting in the driven member having a shift width (Mw) in a predetermined direction; wherein the circumferential direction defines the predetermined direction, or the rotation center line is substantially in parallel to a line in parallel to an orthogonal line orthogonal with the pivoting center line, and the predetermined direction is a direction in parallel to the pivoting center line; wherein a width of the light-receiving surface in the predetermined direction is smaller than the shift width; characterised in that the control unit is configured to control detection of the X-ray beam by the X-ray imaging member to perform X-ray photographing during one continuous turn of the driven member around the rotation center line. an X-ray irradiating unit configured to irradiate an object with an X-ray beam; an X-ray imaging member having a light-receiving surface configured to receive the X-ray beam transmitted through the object; a pivot drive unit configured to cause the X-ray irradiating unit and the X-ray imaging member to have a pivoting motion around the object in a circumferential direction about a pivoting center line (La); and a control unit configured to control the pivot drive unit; a sub-drive unit, controlled by the control unit, configured to cause a driven member which is at least one of the X-ray irradiating unit and the X-ray imaging member to undergo a local motion which is different from the pivoting motion, the local motion being a rotational motion about a rotation center line (Lc) with an interval between the rotation center line and the driven member, and the local motion resulting in the driven member having a shift width (Mw) in a predetermined direction; the circumferential direction defines the predetermined direction, or the rotation center line is substantially in parallel to a line in parallel to an orthogonal line orthogonal with the pivoting center line, and the predetermined direction is a direction in parallel to the pivoting center line;
A pharmaceutical composition comprising a polypeptide selected from the group consisting of SEQ ID NOS: 74-89, 95, 97-99, 102-111, or processed versions thereof, and a pharmaceutically acceptable carrier.
An aqueous flame retardant composition for mineral fibers, in particular glass or rock fibers, characterized in that it comprises: - at least one thermoplastic or thermoset resin; - magnesium hydroxide, Mg 2, and aluminum hydroxide, AIOOH, as flame retarding agents; and - optionally, carbon black. - at least one thermoplastic or thermoset resin; - magnesium hydroxide, Mg 2, and aluminum hydroxide, AIOOH, as flame retarding agents; and - optionally, carbon black.
A method for production of a constitutive plant promoter comprising functionally linking to a promoter one or more nucleic acid expression enhancing nucleic acid (NEENA) molecule heterologous to said promoter comprising i) the nucleic acid molecule having a sequence as defined in SEQ ID NO: 1, or ii) a nucleic acid molecule having a sequence with an identity of at least 80% to SEQ ID NO: 1, or iii) a fragment of 100 or more consecutive bases of a nucleic acid molecule of i) or ii) which has expression enhancing activity as the corresponding nucleic acid molecule having the sequence of SEQ ID NO: 1, or iv) a nucleic acid molecule which is the complement or reverse complement of any of the previously mentioned nucleic acid molecules under i) or ii) wherein said one or more NEENA is functionally linked to the promoter 2500 bp or less away from the transcription start site of said heterologous nucleic acid molecule. i) the nucleic acid molecule having a sequence as defined in SEQ ID NO: 1, or ii) a nucleic acid molecule having a sequence with an identity of at least 80% to SEQ ID NO: 1, or iii) a fragment of 100 or more consecutive bases of a nucleic acid molecule of i) or ii) which has expression enhancing activity as the corresponding nucleic acid molecule having the sequence of SEQ ID NO: 1, or iv) a nucleic acid molecule which is the complement or reverse complement of any of the previously mentioned nucleic acid molecules under i) or ii) wherein said one or more NEENA is functionally linked to the promoter 2500 bp or less away from the transcription start site of said heterologous nucleic acid molecule.
A computer-implemented method for positioning a table in a medical device, the table having a long direction, comprising: obtaining a target image including a subject situated on the table; determining a region of interest of the subject in the target image by segmenting the subject in the target image into a plurality of regions; designating a specific position in the region of interest in the target image; causing the target image to be displayed with a movable identifier on a terminal device, an initial position of the movable identifier corresponding to the specific position of the region of interest of the subject in the target image; obtaining, in the target image, a focus position within the region of interest of the subject, the focus position in the target image indicating a position and/or region of the region of interest to be scanned or treated by the medical device, wherein the obtaining the focus position includes: receiving a user instruction with respect to moving the movable identifier in the target image; and determining the focus position based on the movable identifier moved according to the user instruction; and determining, based on the focus position, a target table position, wherein when the table is at the target table position, the region of interest of the subject is located at an isocenter of the medical device. obtaining a target image including a subject situated on the table; determining a region of interest of the subject in the target image by segmenting the subject in the target image into a plurality of regions; designating a specific position in the region of interest in the target image; causing the target image to be displayed with a movable identifier on a terminal device, an initial position of the movable identifier corresponding to the specific position of the region of interest of the subject in the target image; obtaining, in the target image, a focus position within the region of interest of the subject, the focus position in the target image indicating a position and/or region of the region of interest to be scanned or treated by the medical device, wherein the obtaining the focus position includes: receiving a user instruction with respect to moving the movable identifier in the target image; and determining the focus position based on the movable identifier moved according to the user instruction; and receiving a user instruction with respect to moving the movable identifier in the target image; and determining the focus position based on the movable identifier moved according to the user instruction; and determining, based on the focus position, a target table position, wherein when the table is at the target table position, the region of interest of the subject is located at an isocenter of the medical device.
Method for providing a secure telegram with a useful data part containing useful data and a test data part, wherein the test data part represents unadulterated original useful data, in which - the original useful data is stored in a secure software environment which is embodied as a closed system with regulated access from and to the non-secure part, - a useful data copy of the original useful data is stored outside the secure software environment, - the test data part containing original test data is generated in the secure software environment or outside the secure software environment, and - a test data copy of the original test data is stored outside the secure software environment if the test data part was generated in the secure software environment, - a copy of the useful data copy in the secure software environment is compared with the original useful data and/or a representation of the original useful data, and - a copy of the test data copy in the secure software environment is compared with the original test data and/or the representation of the original test data if the test data copy was stored outside the secure software environment, - the telegram containing the useful data copy as useful data and containing the test data part is provided only if the comparison has shown that the copy of the useful data copy corresponds to the original useful data and - the copy of the test data copy corresponds to the original test data if the test data copy was stored outside the secure software environment. - the original useful data is stored in a secure software environment which is embodied as a closed system with regulated access from and to the non-secure part, - a useful data copy of the original useful data is stored outside the secure software environment, - the test data part containing original test data is generated in the secure software environment or outside the secure software environment, and - a test data copy of the original test data is stored outside the secure software environment if the test data part was generated in the secure software environment, - a copy of the useful data copy in the secure software environment is compared with the original useful data and/or a representation of the original useful data, and - a copy of the test data copy in the secure software environment is compared with the original test data and/or the representation of the original test data if the test data copy was stored outside the secure software environment, - the telegram containing the useful data copy as useful data and containing the test data part is provided only if the comparison has shown that the copy of the useful data copy corresponds to the original useful data and - the copy of the test data copy corresponds to the original test data if the test data copy was stored outside the secure software environment.