mhurhangee/ep-ind-claims huggingface dataset:
A method of calibrating an enzymatic amperometric device for measuring the concentration of creatinine and/or creatine in a sample including one or more enzyme modulators, the method comprising the following steps: Measuring device output for two or more calibration solutions; Determining sensitivities of the device for each of the two or more calibration solutions by calculating a ratio between the output of the device in the calibration solution and the known concentration of creatinine and/or creatine in the calibration solution, wherein each calibration solution has a different amount of the enzyme modulators (step 410); Determining a degree of modulation for each of the two or more calibration solutions by estimating enzyme modulation based on the amounts of enzyme modulators in the calibration solutions (step 420); Determining a degree of modulation for a sample to be measured based on the amounts of enzyme modulators in the sample (step 430); Calculating the sensitivity of the device for the sample, wherein the calculating comprises adjusting the sensitivity of the device for one of the two or more calibration solutions by a factor, wherein the factor is a function of the determined degrees of modulation of the sample and the calibration solution, and wherein the sensitivity for the calibration solution with a degree of enzyme modulation closest to the degree of enzyme modulation of the sample is the sensitivity that is adjusted (step 440). Measuring device output for two or more calibration solutions; Determining sensitivities of the device for each of the two or more calibration solutions by calculating a ratio between the output of the device in the calibration solution and the known concentration of creatinine and/or creatine in the calibration solution, wherein each calibration solution has a different amount of the enzyme modulators (step 410); Determining a degree of modulation for each of the two or more calibration solutions by estimating enzyme modulation based on the amounts of enzyme modulators in the calibration solutions (step 420); Determining a degree of modulation for a sample to be measured based on the amounts of enzyme modulators in the sample (step 430); Calculating the sensitivity of the device for the sample, wherein the calculating comprises adjusting the sensitivity of the device for one of the two or more calibration solutions by a factor, wherein the factor is a function of the determined degrees of modulation of the sample and the calibration solution, and wherein the sensitivity for the calibration solution with a degree of enzyme modulation closest to the degree of enzyme modulation of the sample is the sensitivity that is adjusted (step 440).
A drive arrangement of a vertical roller mill, comprising: a housing, a pressure plate, which is rotatably supported at the housing about the axis of rotation of a vertical pressure plate and which forms an output of the drive arrangement towards the vertical roller mill, a transmission device, which is arranged below the pressure plate in the housing and is supported thereon and is in a rotary drive connection with the pressure plate, and electromotive drive means, which are integrated into the housing below the transmission device and which have at least one rotor (53, 55) with a rotor axis of rotation (R2, R3), which runs parallel to and radially offset from the axis of rotation of the pressure plate, wherein the at least one rotor (53, 55) is in rotary drive connection with the transmission device via a spur gear and the electromotive drive means have a number of at least two electric motors (52, 54) with respective rotors (53, 55), the rotor axis of rotation (R2, R3) of which in each case runs parallel to and radially offset from the axis of rotation of the pressure plate and which in each case are in rotary drive connection with the transmission device via the spur gear, wherein all electric motors (52, 54) are integrated in the housing, so that they are supported or mounted on the latter and preferably accommodated in the outer contour thereof, characterized in that the housing has a cruciform stiffening in a space, which is formed between the electric motors (52, 54), the crossing point of which lies on the axis of rotation of the pressure plate. a housing, a pressure plate, which is rotatably supported at the housing about the axis of rotation of a vertical pressure plate and which forms an output of the drive arrangement towards the vertical roller mill, a transmission device, which is arranged below the pressure plate in the housing and is supported thereon and is in a rotary drive connection with the pressure plate, and electromotive drive means, which are integrated into the housing below the transmission device and which have at least one rotor (53, 55) with a rotor axis of rotation (R2, R3), which runs parallel to and radially offset from the axis of rotation of the pressure plate, wherein the at least one rotor (53, 55) is in rotary drive connection with the transmission device via a spur gear and the electromotive drive means have a number of at least two electric motors (52, 54) with respective rotors (53, 55), the rotor axis of rotation (R2, R3) of which in each case runs parallel to and radially offset from the axis of rotation of the pressure plate and which in each case are in rotary drive connection with the transmission device via the spur gear, wherein all electric motors (52, 54) are integrated in the housing, so that they are supported or mounted on the latter and preferably accommodated in the outer contour thereof, characterized in that the housing has a cruciform stiffening in a space, which is formed between the electric motors (52, 54), the crossing point of which lies on the axis of rotation of the pressure plate.
An object dispensing system, including: a housing (120, 122 & 124) comprising a rotatable carousel, the rotatable carousel retaining a plurality of individually removable containers (220, 224) thereon where each container provides a repository for objects therein; an access port in the housing through which an object may be removed from each of the plurality of containers, in seriatim; a pre-dispense port in the housing providing controlled access to at least a dispense cup; and a retrieval probe, said probe located within the confines of the housing and operatively moving between the access port and the pre-dispense port, said probe including a compliant tip for releasably engaging an object in one of the plurality of containers via said access port, said probe retrieving the object from a container and then moving between the access port and the pre-dispense port to deliver the object to a pre-dispense receptacle. a housing (120, 122 & 124) comprising a rotatable carousel, the rotatable carousel retaining a plurality of individually removable containers (220, 224) thereon where each container provides a repository for objects therein; an access port in the housing through which an object may be removed from each of the plurality of containers, in seriatim; a pre-dispense port in the housing providing controlled access to at least a dispense cup; and a retrieval probe, said probe located within the confines of the housing and operatively moving between the access port and the pre-dispense port, said probe including a compliant tip for releasably engaging an object in one of the plurality of containers via said access port, said probe retrieving the object from a container and then moving between the access port and the pre-dispense port to deliver the object to a pre-dispense receptacle.
A compound of formula: or a pharmaceutically acceptable salt, solvate or stereoisomer thereof, wherein: X is CH 2; R 5 is hydrogen; R 6 is hydrogen or -(C 1 -C 6)alkoxy; R 7 is -SO 2 R 8, -CONR 9 R 10, -(C 1 -C 6)alkyl or -(C 1 -C 6)alkoxy, said alkyl or alkoxy is substituted with one or more NR 9 R 10; R 8 is 6 to 10 membered heterocycle, optionally substituted with (C 1 -C 6)alkyl or (C 6 -C 10)aryl; R 9 is hydrogen, -COO-(C 1 -C 6)alkyl, -(C 0 -C 6)alkyl-CHO, or (C 1 -C 6)alkyl; and R 10 is 6 to 10 membered aryl, -(C 0 -C 6)alkyl-(5 to 10 membered heterocycle), or (C 3 -C 6)cycloalkyl; or R 9 and R 10 together may form an optionally substituted 5 to 6 membered ring containing one or more heteroatoms. X is CH 2; R 5 is hydrogen; R 6 is hydrogen or -(C 1 -C 6)alkoxy; R 7 is -SO 2 R 8, -CONR 9 R 10, -(C 1 -C 6)alkyl or -(C 1 -C 6)alkoxy, said alkyl or alkoxy is substituted with one or more NR 9 R 10; R 8 is 6 to 10 membered heterocycle, optionally substituted with (C 1 -C 6)alkyl or (C 6 -C 10)aryl; R 9 is hydrogen, -COO-(C 1 -C 6)alkyl, -(C 0 -C 6)alkyl-CHO, or (C 1 -C 6)alkyl; and R 10 is 6 to 10 membered aryl, -(C 0 -C 6)alkyl-(5 to 10 membered heterocycle), or (C 3 -C 6)cycloalkyl; or R 9 and R 10 together may form an optionally substituted 5 to 6 membered ring containing one or more heteroatoms.
A gene delivery vector comprising i) an endonuclease, and ii) at least one single guide RNA (sgRNA), or crRNA and tracrRNA, targeting a regulatory sequence of an lncRNA associated with cardiac-specific super-enhancers (SEs), wherein the one or more lncRNA associated with cardiac-specific super-enhancers (SEs) is selected from the group comprising Wisper, Sparc, Col15A1, Cyr61, and Smad7, and wherein the regulatory sequence is a promoter or an enhancer sequence selected from the group comprising the proximal Wisper enhancer (SEQ ID No. 1), the proximal Wisper promoter (SEQ ID No. 2), the Wisper super-enhancer (SEQ ID No. 3), the Wisper downstream cis sequence (SEQ ID No. 4), the Smad7 cis-regulatory sequence (SEQ ID No. 5), the Cyr61 cis-regulatory sequence (SEQ ID No. 6), the Col15A1 cis-regulatory sequence (SEQ ID No.7), and the Sparc cis-regulatory sequence (SEQ ID No. 8). i) an endonuclease, and ii) at least one single guide RNA (sgRNA), or crRNA and tracrRNA, targeting a regulatory sequence of an lncRNA associated with cardiac-specific super-enhancers (SEs),
A system comprising: a debug control interface, DCI, unit; a Type-C connector; a Universal Serial Bus, USB, physical, phy, interface coupled to the Type-C connector, the USB phy interface having at least one transceiver, lanes between the at least one transceiver of the USB phy interface and the Type-C connector being configured for receiving or transmitting DCI signals based on configuration channel, CC, pin detection and orientation; and interface logic coupled to the DCI unit and the USB phy interface to exchange debug control interface, DCI, signaling between the connector and the DCI unit, wherein USB D+ and/or USB D- lanes of the Type-C connector are used for exchanging the DCI signaling and the DCI signaling including boundary scan side band, BSSB, control and data signals. a debug control interface, DCI, unit; a Type-C connector; a Universal Serial Bus, USB, physical, phy, interface coupled to the Type-C connector, the USB phy interface having at least one transceiver, lanes between the at least one transceiver of the USB phy interface and the Type-C connector being configured for receiving or transmitting DCI signals based on configuration channel, CC, pin detection and orientation; and interface logic coupled to the DCI unit and the USB phy interface to exchange debug control interface, DCI, signaling between the connector and the DCI unit, wherein USB D+ and/or USB D- lanes of the Type-C connector are used for exchanging the DCI signaling and the DCI signaling including boundary scan side band, BSSB, control and data signals.
Passenger seat device, in particular flight passenger seat device, with a seat part comprising a seat surface, with a seat direction and with a base body which, when installed in a transport means, borders on an aisle and in a use position laterally covers the seat surface in a region beside the seat surface with respect to the seat surface, with a support unit for movably supporting the base body which is provided to adjust the base body from the use position into a release position by a movement relative to the seat surface causing a release of the region beside the seat surface, and with a pivoting device for supporting the base body pivotably with respect to the seat surface, characterised in that the pivoting device comprises at least two different pivot axes (58, 66), one of the pivot axes being provided for an inclining movement of the base body with respect to a vertical direction prior to pivoting about the other pivot axis into the release position.
An ultrasound endoscope comprising: an ultrasound transducer section that includes a rectangular upper face, and transmits/receives ultrasound from the upper face; a cable including an end electrically connected to the ultrasound transducer section; an acoustic lens that covers the upper face and side faces of the ultrasound transducer section, wherein, as viewed in a direction facing the upper face, the acoustic lens has a rectangular shape whose longitudinal direction is aligned with that of the rectangular upper face of the ultrasound transducer section; a housing that is a casing housing the ultrasound transducer section and the acoustic lens, the housing including a rectangular first opening portion in which the acoustic lens is fitted, and a second opening portion via which the cable is drawn out from an inside of the first opening portion; and an adhesive that secures the acoustic lens and the ultrasound transducer section housed in the housing, characterized in that the acoustic lens includes a chamfered portion formed in at least one corner from among four corners of the rectangular shape as viewed in a direction facing the upper face, the chamfered portion resulting from the corner being cut off, the housing includes an adhesive outlet port being a gap formed between the chamfered portion and a corner of the first opening portion, wherein during manufacture the adhesive is charged inside the housing and fills and flows out from the adhesive outlet port. an ultrasound transducer section that includes a rectangular upper face, and transmits/receives ultrasound from the upper face; a cable including an end electrically connected to the ultrasound transducer section; an acoustic lens that covers the upper face and side faces of the ultrasound transducer section, wherein, as viewed in a direction facing the upper face, the acoustic lens has a rectangular shape whose longitudinal direction is aligned with that of the rectangular upper face of the ultrasound transducer section; a housing that is a casing housing the ultrasound transducer section and the acoustic lens, the housing including a rectangular first opening portion in which the acoustic lens is fitted, and a second opening portion via which the cable is drawn out from an inside of the first opening portion; and an adhesive that secures the acoustic lens and the ultrasound transducer section housed in the housing, characterized in that the acoustic lens includes a chamfered portion formed in at least one corner from among four corners of the rectangular shape as viewed in a direction facing the upper face, the chamfered portion resulting from the corner being cut off, the housing includes an adhesive outlet port being a gap formed between the chamfered portion and a corner of the first opening portion, wherein during manufacture the adhesive is charged inside the housing and fills and flows out from the adhesive outlet port.
A method for fabricating a Group III-V compound semiconductor solar cell device, the method comprising the steps of: forming at least one cell unit (203, 205, 207; 603) from a Group III-V compound semiconductor material, the cell unit (203, 205, 207; 603) being configured to absorb predetermined wavelengths of a solar spectrum; forming an unoxidized window layer on the cell unit (203, 205, 207; 603) to prevent recombination of photo-generated carriers at a top surface of the solar cell device; providing a cap layer on the unoxidized window layer to enhance an electrical contact with a metal conductive material; etching the cap layer to expose at least a portion of the unoxidized window layer; and oxidizing the unoxidized window layer to convert the unoxidized window layer to an oxidized window layer (209; 609), wherein the step of oxidizing includes the further steps of: once the unit cell (203, 205, 207; 603) is formed, subjecting the unit cell (203, 205, 207; 603) to a wet oxidation technique including placing the cell unit (203, 205, 207; 603) with the unoxidized window layer in a chamber of a furnace, and oxidizing the exposed portion of the unoxidized window layer using the wet oxidation technique at a temperature above 100°C, the exposed portion corresponding to an etched portion of the cap layer. forming at least one cell unit (203, 205, 207; 603) from a Group III-V compound semiconductor material, the cell unit (203, 205, 207; 603) being configured to absorb predetermined wavelengths of a solar spectrum; forming an unoxidized window layer on the cell unit (203, 205, 207; 603) to prevent recombination of photo-generated carriers at a top surface of the solar cell device; providing a cap layer on the unoxidized window layer to enhance an electrical contact with a metal conductive material; etching the cap layer to expose at least a portion of the unoxidized window layer; and oxidizing the unoxidized window layer to convert the unoxidized window layer to an oxidized window layer (209; 609), wherein the step of oxidizing includes the further steps of: once the unit cell (203, 205, 207; 603) is formed, subjecting the unit cell (203, 205, 207; 603) to a wet oxidation technique including placing the cell unit (203, 205, 207; 603) with the unoxidized window layer in a chamber of a furnace, and oxidizing the exposed portion of the unoxidized window layer using the wet oxidation technique at a temperature above 100°C, the exposed portion corresponding to an etched portion of the cap layer. once the unit cell (203, 205, 207; 603) is formed, subjecting the unit cell (203, 205, 207; 603) to a wet oxidation technique including placing the cell unit (203, 205, 207; 603) with the unoxidized window layer in a chamber of a furnace, and oxidizing the exposed portion of the unoxidized window layer using the wet oxidation technique at a temperature above 100°C, the exposed portion corresponding to an etched portion of the cap layer.
Frozen enzyme formulation comprising an enzyme, wherein the frozen enzyme formulation is in the form of frozen pellets, wherein the water content is at least 20% (w/w), and wherein the pellets are granula having an average diameter of between 0.01 and 15 mm. wherein the frozen enzyme formulation is in the form of frozen pellets, wherein the water content is at least 20% (w/w), and wherein the pellets are granula having an average diameter of between 0.01 and 15 mm.
A method performed by a User Equipment, in the following also referred to as UE, characterized by: determining whether a beam used by the UE for communications and associated with a reference signal of a cell is affected by an In-Device Coexistence, in the following also referred to as IDC, problem which relates to an IDC interference between communications performed by radio transceivers of the UE; determining whether to include information associated with the reference signal in a report based on whether the beam associated with the reference signal is affected by the IDC problem; and transmitting the report to a network node. determining whether a beam used by the UE for communications and associated with a reference signal of a cell is affected by an In-Device Coexistence, in the following also referred to as IDC, problem which relates to an IDC interference between communications performed by radio transceivers of the UE; determining whether to include information associated with the reference signal in a report based on whether the beam associated with the reference signal is affected by the IDC problem; and transmitting the report to a network node.
A turbocharger assembly comprising: a shaft sleeve that comprises a bore that extends between a first end and a second end; a shaft received by the bore of the shaft sleeve wherein the shaft comprises a compressor end and a turbine wheel that defines a turbine end; a bearing assembly seated with respect to the shaft sleeve; and a balance collar disposed on the shaft and seated axially between the second end of the shaft sleeve and the turbine wheel wherein the balance collar comprises a stepped bore, a stem portion and a flared portion that comprises a sacrificial portion, wherein the stepped bore comprises an annular axial face that extends to a shoulder contour as a surface that extends to an end of the flared portion,, wherein the sacrificial portion is disposed over an axial length of the balance collar that does not overlap axially with the stem portion of the balance collar and is disposed at a radial distance greater than an outermost radius of the stem portion of the balance collar, characterized in that, an axial face surface of a hub portion of the shaft seats against the annular axial face of the stepped bore of the balance collar, wherein the stem portion of the balance collar is loaded by an axial load between the second end of the shaft sleeve and the axial face surface of the hub portion of the shaft. a shaft sleeve that comprises a bore that extends between a first end and a second end; a shaft received by the bore of the shaft sleeve wherein the shaft comprises a compressor end and a turbine wheel that defines a turbine end; a bearing assembly seated with respect to the shaft sleeve; and a balance collar disposed on the shaft and seated axially between the second end of the shaft sleeve and the turbine wheel wherein the balance collar comprises a stepped bore, a stem portion and a flared portion that comprises a sacrificial portion, wherein the stepped bore comprises an annular axial face that extends to a shoulder contour as a surface that extends to an end of the flared portion,, wherein the sacrificial portion is disposed over an axial length of the balance collar that does not overlap axially with the stem portion of the balance collar and is disposed at a radial distance greater than an outermost radius of the stem portion of the balance collar, characterized in that, an axial face surface of a hub portion of the shaft seats against the annular axial face of the stepped bore of the balance collar, wherein the stem portion of the balance collar is loaded by an axial load between the second end of the shaft sleeve and the axial face surface of the hub portion of the shaft.
A customizable shoe last comprising: a solid portion and an adjustable portion, the adjustable portion to comprise a moldable material that is selectively solidifiable for footwear manufacture; an interchangeable mold cover to enclose the adjustable portion; characterised in that a backpressure cavity arranged with respect to the adjustable portion to put pressure on moldable material of the adjustable portion. a solid portion and an adjustable portion, the adjustable portion to comprise a moldable material that is selectively solidifiable for footwear manufacture; an interchangeable mold cover to enclose the adjustable portion; characterised in that a backpressure cavity arranged with respect to the adjustable portion to put pressure on moldable material of the adjustable portion.