A recombinant yeast strain, suitable for the expression of infectious measles virus Ribonucleocapsids (RNPs) or infectious RNPs-like, wherein the yeast is transformed with the following expression vectors: (i) a genome vector, especially a plasmid genome vector, comprising, as an insert operatively linked with expression control sequences including a yeast promoter, a cloned DNA molecule which comprises a cDNA encoding the (+) strand full-length sequence (antigenome) of said measles virus, and wherein said cDNA is flanked, in the cloned DNA molecule, by autocatalytic ribozyme sequences enabling the recovery of RNA after transcription and replication, having original 3' and 5' ends, of the genome of said measles virus, (ii) a genome vector, preferably a plasmid genome vector, comprising, as an insert under the control of regulatory expression sequences including a yeast promoter, a cloned DNA molecule which comprises a cDNA encoding part of the antigenome of said measles virus including in the 5' to 3' orientation, a viral Terminator sequence, a polynucleotide which codes a selectable marker cloned in sense orientation with respect to the cis-acting sequences of said measles virus and the Leader sequence of said measles virus, (iii) one or more trans-complementation vectors comprising, under the control of regulation expression sequences including a yeast promoter, nucleotide sequences which enable said vector(s) to collectively express the Nucleoprotein, the Phosphoprotein and the Polymerase or derivatives thereof necessary for the synthesis of the viral transcriptase complex of said measles virus used in the genome vector, and enable assembly of the ribonucleocapsid (RNPs) of said measles virus or assembly of RNPs-like comprising recombinant RNA derived from viral RNA of a measles virus, wherein the RNPs or RNPs-like are functional for the replication and transcription, each of said vector(s) further comprising, under the control of regulatory expression sequences including a yeast promoter, a selectable marker, wherein in said vectors all the selectable markers are different from each other, and wherein the vector encoding the viral L polymerase of said measles virus is a priming plasmid harbouring the CAN1 gene, wherein the yeast strain is mutated in the CAN1 gene. (i) a genome vector, especially a plasmid genome vector, comprising, as an insert operatively linked with expression control sequences including a yeast promoter, a cloned DNA molecule which comprises a cDNA encoding the (+) strand full-length sequence (antigenome) of said measles virus, and wherein said cDNA is flanked, in the cloned DNA molecule, by autocatalytic ribozyme sequences enabling the recovery of RNA after transcription and replication, having original 3' and 5' ends, of the genome of said measles virus, (ii) a genome vector, preferably a plasmid genome vector, comprising, as an insert under the control of regulatory expression sequences including a yeast promoter, a cloned DNA molecule which comprises a cDNA encoding part of the antigenome of said measles virus including in the 5' to 3' orientation, a viral Terminator sequence, a polynucleotide which codes a selectable marker cloned in sense orientation with respect to the cis-acting sequences of said measles virus and the Leader sequence of said measles virus, (iii) one or more trans-complementation vectors comprising, under the control of regulation expression sequences including a yeast promoter, nucleotide sequences which enable said vector(s) to collectively express the Nucleoprotein, the Phosphoprotein and the Polymerase or derivatives thereof necessary for the synthesis of the viral transcriptase complex of said measles virus used in the genome vector, and enable assembly of the ribonucleocapsid (RNPs) of said measles virus or assembly of RNPs-like comprising recombinant RNA derived from viral RNA of a measles virus, wherein the RNPs or RNPs-like are functional for the replication and transcription, each of said vector(s) further comprising, under the control of regulatory expression sequences including a yeast promoter, a selectable marker, wherein in said vectors all the selectable markers are different from each other, and wherein the vector encoding the viral L polymerase of said measles virus is a priming plasmid harbouring the CAN1 gene,