A method for selection of image points in the representation of an object in intraoperative imaging, in particular a biological tissue, comprising the steps of: a) Generating a first image of at least a sub-region of the object by means of an endoscopy device as a first device; b) Generating a second image (8, 8') of at least the sub-region of the object from step a) by means of a second device; c) Ascertaining first coordinates of at least some image points of the second image in a first coordinate system; d) Asceratining second coordinates of the image points of the second image by mapping the first coordinates into a second coordinate system, which is different from the first coordinate system and is assigned to the first device; and e) Generating a combined image of the object from the first image and for selected image points from the second image using the determined second coordinates of the image points of the second image, characterized in that f) the selection of image points to be combined is determined by the selection of a subarea of the object, wherein • the first device comprises a light source and the subarea of the object to be selected is marked by generating at least one light spot on the object with aid of the light source, or • the subarea of the object is marked with a separate, navigated instrument, g) such that generating of the combined image in the intraoperative imaging occurs by replacing or superimposing image points of the first image within the selected subarea of the object through the selected image points of the second image. a) Generating a first image of at least a sub-region of the object by means of an endoscopy device as a first device; b) Generating a second image (8, 8') of at least the sub-region of the object from step a) by means of a second device; c) Ascertaining first coordinates of at least some image points of the second image in a first coordinate system; d) Asceratining second coordinates of the image points of the second image by mapping the first coordinates into a second coordinate system, which is different from the first coordinate system and is assigned to the first device; and e) Generating a combined image of the object from the first image and for selected image points from the second image using the determined second coordinates of the image points of the second image, characterized in that f) the selection of image points to be combined is determined by the selection of a subarea of the object, wherein • the first device comprises a light source and the subarea of the object to be selected is marked by generating at least one light spot on the object with aid of the light source, or • the subarea of the object is marked with a separate, navigated instrument, • the first device comprises a light source and the subarea of the object to be selected is marked by generating at least one light spot on the object with aid of the light source, or • the subarea of the object is marked with a separate, navigated instrument, g) such that generating of the combined image in the intraoperative imaging occurs by replacing or superimposing image points of the first image within the selected subarea of the object through the selected image points of the second image.