An anti-extravasation system comprising: a catheter having a length and an outer diameter suitable for extending from a peripheral vein insertion point on a patient to a treatment site, said catheter having a venous section and an interstitial section and comprising: an inner tube having a central lumen; an outer tube disposed about the inner tube; a plurality of ribs extending between the inner and outer tubes (24, 25) and running along the length of the catheter; wherein the inner tube, the outer tube and the plurality of ribs bound a plurality of outer lumens that extend between the inner and outer tubes (24, 25) and that run along the length of the catheter; and a plurality of drainage apertures disposed in an interstitial section of the outer tube, said drainage apertures in fluid communication with one or more drainage lumens and adapted to drain fluid from tissue surrounding the insertion point when the catheter is operably disposed within the patient; a hub placed in fluid communication with the central lumen and the plurality of drainage lumens; a reservoir of chemotherapy therapeutic fluid source in fluid communication with the hub in fluid communication with the central lumen; and a vacuum source in fluid communication with the hub in fluid communication with the plurality of drainage lumens. a catheter having a length and an outer diameter suitable for extending from a peripheral vein insertion point on a patient to a treatment site, said catheter having a venous section and an interstitial section and comprising: an inner tube having a central lumen; an outer tube disposed about the inner tube; a plurality of ribs extending between the inner and outer tubes (24, 25) and running along the length of the catheter; wherein the inner tube, the outer tube and the plurality of ribs bound a plurality of outer lumens that extend between the inner and outer tubes (24, 25) and that run along the length of the catheter; and a plurality of drainage apertures disposed in an interstitial section of the outer tube, said drainage apertures in fluid communication with one or more drainage lumens and adapted to drain fluid from tissue surrounding the insertion point when the catheter is operably disposed within the patient; an inner tube having a central lumen; an outer tube disposed about the inner tube; a plurality of ribs extending between the inner and outer tubes (24, 25) and running along the length of the catheter; wherein the inner tube, the outer tube and the plurality of ribs bound a plurality of outer lumens that extend between the inner and outer tubes (24, 25) and that run along the length of the catheter; and a plurality of drainage apertures disposed in an interstitial section of the outer tube, said drainage apertures in fluid communication with one or more drainage lumens and adapted to drain fluid from tissue surrounding the insertion point when the catheter is operably disposed within the patient; a hub placed in fluid communication with the central lumen and the plurality of drainage lumens; a reservoir of chemotherapy therapeutic fluid source in fluid communication with the hub in fluid communication with the central lumen; and a vacuum source in fluid communication with the hub in fluid communication with the plurality of drainage lumens.