A vascular coupling device, comprising - a first and a second coupling element (21, 22) wherein each one of said first and second coupling elements (21, 22) has an external surface (23', 23") facing an external side, a coupling surface (25', 25") facing a coupling side, and a central opening (27', 27"); and - a first and a second tubular connecting element (31, 32), wherein each one of said first and second tubular elements (31, 32) has a first open end (33', 33") and a second open end (37, 38), said first open ends (33', 33") being provided with flanges (34', 34"); each one of said first and second tubular connecting elements (31, 32) is arranged in a corresponding central opening (27', 27") of the first and second coupling elements (21, 22) respectively, and with said second open ends (37, 38) protruding through said central openings (27', 27") on said external side of each of said first and second coupling elements (21, 22); said first and second coupling elements (21, 22) being removably connected to each other into a locked configuration, or disconnected from each other into an unlocked configuration by means of a first and second locking structure (41, 42), said first and second locking structures (41, 42) being arranged on a centerline A of the vascular coupling device, and opposite to each other on an outer perimeter of said vascular coupling device, characterized in that said vascular device further comprises a fail-safe arrangement comprising first and second cut-in portions (91, 92) arranged on said first coupling element configured to receive first and second projecting elements (93, 94) arranged on said second coupling element, said first and second cut-in portions (91, 92) and first and second projecting element (93, 94) being arranged on same side of said centerline A, thereby preventing erroneous connection of said first and second coupling elements (21, 22) to each other. - a first and a second coupling element (21, 22) wherein each one of said first and second coupling elements (21, 22) has an external surface (23', 23") facing an external side, a coupling surface (25', 25") facing a coupling side, and a central opening (27', 27"); and - a first and a second tubular connecting element (31, 32), wherein each one of said first and second tubular elements (31, 32) has a first open end (33', 33") and a second open end (37, 38), said first open ends (33', 33") being provided with flanges (34', 34"); said first and second coupling elements (21, 22) being removably connected to each other into a locked configuration, or disconnected from each other into an unlocked configuration by means of a first and second locking structure (41, 42), said first and second locking structures (41, 42) being arranged on a centerline A of the vascular coupling device, and opposite to each other on an outer perimeter of said vascular coupling device, characterized in that said vascular device further comprises a fail-safe arrangement comprising first and second cut-in portions (91, 92) arranged on said first coupling element configured to receive first and second projecting elements (93, 94) arranged on said second coupling element, said first and second cut-in portions (91, 92) and first and second projecting element (93, 94) being arranged on same side of said centerline A, thereby preventing erroneous connection of said first and second coupling elements (21, 22) to each other.