mhurhangee/ep-ind-claims huggingface dataset:
Use of a compound of formula wherein: - R 1 represents a hydrogen atom, a C 1 -C 4 alkyl, a halogen atom, -OH, -CN, -CF 3, -C(=O)NH 2, -C(=O)O -, or -C(=O)O-R 5 where R 5 represents H or a C 1 -C 4 alkyl, - R 2 is -SO 2 NH 2, a hydrogen atom, a halogen atom, a C 1 -C 4 alkyl, -OH, -CN, -C(=O)NH 2, - CF 3, or -C(=O)OR 6 where R 6 represents H or a C 1 -C 4 alkyl, - R 3 is H, a halogen atom, a C 1 -C 4 alkyl, -OH, -CN, -C(=O)NH 2,-CF 3, or -C(=O)OR 7 where R 7 represents H or a C 1 -C 4 alkyl, and - R 4 represents a hydrogen atom, -OH, or -OCH 3, or a pharmaceutically acceptable salt thereof, in the preparation of a chemical model of a synucleinopathy, preferably Parkinson's disease, by placing a cell system selected from a cell, a cell culture, a tissue, and a non-human animal, in contact with said compound. - R 1 represents a hydrogen atom, a C 1 -C 4 alkyl, a halogen atom, -OH, -CN, -CF 3, -C(=O)NH 2, -C(=O)O -, or -C(=O)O-R 5 where R 5 represents H or a C 1 -C 4 alkyl, - R 2 is -SO 2 NH 2, a hydrogen atom, a halogen atom, a C 1 -C 4 alkyl, -OH, -CN, -C(=O)NH 2, - CF 3, or -C(=O)OR 6 where R 6 represents H or a C 1 -C 4 alkyl, - R 3 is H, a halogen atom, a C 1 -C 4 alkyl, -OH, -CN, -C(=O)NH 2,-CF 3, or -C(=O)OR 7 where R 7 represents H or a C 1 -C 4 alkyl, and - R 4 represents a hydrogen atom, -OH, or -OCH 3,
Method for determining a fill level of a medium according to the radar principle, wherein at least one electromagnetic signal is emitted by a transmitting device and at least one electromagnetic signal is received for the determination of the fill level, wherein an inclination of the transmitting device is determined relative to the earth's gravity field at least once and wherein at least one evaluation value for determining the fill level is determined at least depending on the determined inclination, characterized in that signal path data are determined at least depending on the determined inclination and depending on data about the container, wherein the signal path data describe a propagation of the at least one electromagnetic signal in the interior of the container, and that, based on the signal path data and the data about the container, a radiation measure is determined, wherein the radiation measure describes a proportion of the propagation of the at least one electromagnetic signal outside the interior of the container.
A process for the feeding of fish providing edible fish meat, characterized in that the feeding process comprises at least two consecutive stages, wherein - in a stage I juvenile fish are fed with a feed of high protein and low fat content, said feed having a protein content of at least 48%; a fish oil content of at least 5%; and a fat content not higher than 12% relative to the total weight of said feed, the daily portion of said feed in stage I being not more than 1.2% of the metabolic body weight (MBW%) of the fish, wherein said metabolic body weight is equal to the body weight raised to the power of 0.8: MBW=W 0.8, wherein W is the kg body weight of the fish; to decrease the levels of saturated and monounsaturated fatty acids of the fish meat relative to the weight of the fish and simultaneously accelerate growth of the fish, then - in a subsequent stage II juvenile fish are fed with a feed having a fatty acid content of increased level(s) of one or more long chain polyunsaturated fatty acid(s) (LcPUFA), said feed having a fat content of at least 14%, to deposit the one or more LcPUFA in the fish meat, thereby increasing the level(s) of said LcPUFA(s) relative to the weight of the fish and the ratio of LcPUFA(s) to monounsaturated fatty acids in the flesh of the fish. - in a stage I juvenile fish are fed with a feed of high protein and low fat content, said feed having a protein content of at least 48%; a fish oil content of at least 5%; and a fat content not higher than 12% relative to the total weight of said feed, the daily portion of said feed in stage I being not more than 1.2% of the metabolic body weight (MBW%) of the fish, wherein said metabolic body weight is equal to the body weight raised to the power of 0.8: MBW=W 0.8, wherein W is the kg body weight of the fish; to decrease the levels of saturated and monounsaturated fatty acids of the fish meat relative to the weight of the fish and simultaneously accelerate growth of the fish, then - in a subsequent stage II juvenile fish are fed with a feed having a fatty acid content of increased level(s) of one or more long chain polyunsaturated fatty acid(s) (LcPUFA), said feed having a fat content of at least 14%, to deposit the one or more LcPUFA in the fish meat, thereby increasing the level(s) of said LcPUFA(s) relative to the weight of the fish and the ratio of LcPUFA(s) to monounsaturated fatty acids in the flesh of the fish.
A method for configuring a motion sensor comprising an accelerometer and/or a gyroscope, a processing unit, a memory unit, a program selection means, a wireless transmitting unit, and a receiving unit, the method comprising: - providing configuration data to the program selection means; - selecting by the program selection means a signal processing program from a plurality of signal processing programs stored in the memory unit dependent on the provided configuration data; - determining by the processing unit at least one motion parameter from one or more output signals of the accelerometer and/or the gyroscope using the selected signal processing program; - selecting a transmission protocol program from a plurality of transmission protocol programs stored in the memory unit dependent on the provided configuration data; and - sending by the wireless transmitting unit the at least one motion parameter or the one or more output signals of the accelerometer and/or the gyroscope or one or more signals based on said output signals using the selected transmission protocol program, wherein at least one of the plurality of signal processing programs and/or at least one of the plurality of transmission protocol programs is received by the receiving unit. - providing configuration data to the program selection means; - selecting by the program selection means a signal processing program from a plurality of signal processing programs stored in the memory unit dependent on the provided configuration data; - determining by the processing unit at least one motion parameter from one or more output signals of the accelerometer and/or the gyroscope using the selected signal processing program; - selecting a transmission protocol program from a plurality of transmission protocol programs stored in the memory unit dependent on the provided configuration data; and - sending by the wireless transmitting unit the at least one motion parameter or the one or more output signals of the accelerometer and/or the gyroscope or one or more signals based on said output signals using the selected transmission protocol program,
A turbine having variable turbine geometry for use in a combustion engine comprising a bearing housing; a turbine housing; a cartridge, which features a vane bearing ring for supporting a plurality of adjustable vanes; and a shield ring, the shield ring is arranged radially outward of the vane bearing ring, the turbine being characterised in that a seal is arranged radially outward of the shield ring between the shield ring and the turbine housing, and in that the seal is arranged in axial direction between a second ledge on the interior surface of the turbine housing and a radial side surface of the bearing housing.
A bi-directional repeater having a switchable antenna port, comprising: a switchable common port; a switchable second-band port; a first-band amplification and filtering path coupled to the switchable common port via a first path of a first multiplexer; characterized by said repeater further comprising a second-band amplification and filtering path coupled to one of: the switchable common port via a second path of the first multiplexer, a first path of a first radio frequency switch, and a first path of a second multiplexer; or the switchable second-band port via the first path of the second multiplexer, and a second path of the first RF switch. a switchable common port; a switchable second-band port; a first-band amplification and filtering path coupled to the switchable common port via a first path of a first multiplexer; characterized by said repeater further comprising a second-band amplification and filtering path coupled to one of: the switchable common port via a second path of the first multiplexer, a first path of a first radio frequency switch, and a first path of a second multiplexer; or the switchable second-band port via the first path of the second multiplexer, and a second path of the first RF switch. the switchable common port via a second path of the first multiplexer, a first path of a first radio frequency switch, and a first path of a second multiplexer; or the switchable second-band port via the first path of the second multiplexer, and a second path of the first RF switch.
Method for the production of solar cells, comprising the production of a monograin membrane with the steps: providing a layer consisting of an electrically non-conductive binder on a carrier layer; partially introducing of grains through a surface of the layer consisting of a binder into the layer; wherein the grains consist of a material which is capable of converting sunlight into electrical energy; solidifying the electrically non-conductive binder into which the grains have been introduced, characterized in that the carrier film is unwound from a roll, a web which consists of alternating sections is continuously produced on the carrier layer, wherein a first section comprises the aforementioned layer with the electrically non-conductive binder together with grains protruding therefrom and a second web or strip-shaped electrically conductive section adjacent thereto comprises a layer or areas of electrically conductive material and these two sections alternate several times, the surface of the electrically non-conductive and electrically conductive sections thus produced is covered in sections in a web-like manner with a transparent, electrically conductive material in such a way that each web-like section is connected to only one electrically conductive section underneath; subsequently the carrier is removed and the surface thus exposed is covered with electrically conductive material in a web-like manner as well as in sections, in such a way that each web-like section is connected to only one electrically conductive section underneath, so that individual solar cells are electrically serially connected with each other. providing a layer consisting of an electrically non-conductive binder on a carrier layer; partially introducing of grains through a surface of the layer consisting of a binder into the layer; wherein the grains consist of a material which is capable of converting sunlight into electrical energy; solidifying the electrically non-conductive binder into which the grains have been introduced, characterized in that the carrier film is unwound from a roll, a web which consists of alternating sections is continuously produced on the carrier layer, wherein a first section comprises the aforementioned layer with the electrically non-conductive binder together with grains protruding therefrom and a second web or strip-shaped electrically conductive section adjacent thereto comprises a layer or areas of electrically conductive material and these two sections alternate several times, the surface of the electrically non-conductive and electrically conductive sections thus produced is covered in sections in a web-like manner with a transparent, electrically conductive material in such a way that each web-like section is connected to only one electrically conductive section underneath; subsequently the carrier is removed and the surface thus exposed is covered with electrically conductive material in a web-like manner as well as in sections, in such a way that each web-like section is connected to only one electrically conductive section underneath, so that individual solar cells are electrically serially connected with each other.
An anchor (9; 10) for use as a leaflet anchor or a papillary anchor for implantation in heart tissue to hold a line, the anchor (9; 10) comprising a number of hooks for engagement with the heart tissue and having a folded position and an unfolded position, wherein the anchor (9; 10) is made of an elastic material such that it can be elastically deformed into the folded position by application of a constraining force, and will return to the unfolded position when no constraining force is applied, characterised in that: the hooks are formed with openings (64, 66) along their length, wherein the openings (64, 66) in the hooks comprise slits extending along some or all of the length of the hooks.
A bogie for a railway vehicle, comprising: - a frame; - at least one axle; - at least one axle box, internally receiving the at least one axle; - a suspension of the or each axlebox on the frame; the suspension comprising: - an arm supporting the axle box; and - at least one elastic member interposed between the arm and the frame; the frame comprising, for the or each elastic member, a cavity for receiving said elastic member, the cavity comprising an opening and a bottom, an upper end of the elastic member being engaged in the cavity through the opening and bearing on the bottom, characterized in that the bogie comprises two elastic members, a first elastic member bearing on a bearing region offset longitudinally forwards with respect to the axle, and a second elastic member bearing on a bearing region offset rearwards with respect to the axle. - a frame; - at least one axle; - at least one axle box, internally receiving the at least one axle; - a suspension of the or each axlebox on the frame; - an arm supporting the axle box; and - at least one elastic member interposed between the arm and the frame; the frame comprising, for the or each elastic member, a cavity for receiving said elastic member, the cavity comprising an opening and a bottom, an upper end of the elastic member being engaged in the cavity through the opening and bearing on the bottom, characterized in that the bogie comprises two elastic members, a first elastic member bearing on a bearing region offset longitudinally forwards with respect to the axle, and a second elastic member bearing on a bearing region offset rearwards with respect to the axle.
A roll-forming manufacturing method of a roller bearing seal case, comprising: roll-forming, from a cylindrical ring, a profiled ring including a first section extending at least along a cylinder axis of the cylindrical ring and a second section extending from the first section inward toward the cylinder axis, the second section being contiguous with the first section and defining a first aperture about the cylinder axis, said roll-forming comprising bending a part of the cylindrical ring that encircles the cylinder axis toward the cylinder axis to form the second section; and characterised by trimming the second section to expand the first aperture into a second aperture with location and geometry according to design parameters, wherein said trimming includes stamping out the second aperture to expand the first diameter, which deviates from perfect circularity, into the second aperture, the second aperture having improved circularity over the first aperture. roll-forming, from a cylindrical ring, a profiled ring including a first section extending at least along a cylinder axis of the cylindrical ring and a second section extending from the first section inward toward the cylinder axis, the second section being contiguous with the first section and defining a first aperture about the cylinder axis, said roll-forming comprising bending a part of the cylindrical ring that encircles the cylinder axis toward the cylinder axis to form the second section; and characterised by trimming the second section to expand the first aperture into a second aperture with location and geometry according to design parameters, wherein said trimming includes stamping out the second aperture to expand the first diameter, which deviates from perfect circularity, into the second aperture, the second aperture having improved circularity over the first aperture.
A chemical oxygen generator system for the provision of oxygen in an aircraft, comprising a regulation device for a source of oxygen, the regulation device comprising: - a housing having an annular wall, a first chamber and a second chamber, a wall separating the first chamber and the second chamber, - a reaction medium arranged within the first chamber and adapted to perform an exothermic reaction for the production of reaction gas comprising oxygen, the reaction medium having an annular shape and surrounding an interior reaction volume having a reaction gas inlet and a first reaction gas outlet, the second chamber having a second reaction gas outlet for directing reaction gas to a passenger in an aircraft, - an igniter for triggering the exothermic reaction of the reaction medium, - an exterior reaction volume being arranged within the first chamber between the reaction medium and the annular wall of the housing, and - a flow regulator arranged at the first reaction gas outlet and adapted to throttle the flow of reaction gas through the first reaction gas outlet based on an increase in temperature of the regulation device, wherein the regulation device is adapted to direct a flow of reaction gas through the exterior reaction volume on its way to the reaction gas inlet of the interior reaction volume, wherein the wall forces reaction gas to flow through the exterior reaction volume towards the reaction gas inlet of the interior reaction volume, the flow of reaction gas is directed from the interior reaction volume through the first reaction gas outlet and the flow regulator into the second chamber and to the second reaction gas outlet, wherein the wall has an aperture for flow of reaction gas from the first reaction gas outlet to the flow regulator, and wherein the reaction medium abuts the wall at the first reaction gas outlet. - a housing having an annular wall, a first chamber and a second chamber, a wall separating the first chamber and the second chamber, - a reaction medium arranged within the first chamber and adapted to perform an exothermic reaction for the production of reaction gas comprising oxygen, the reaction medium having an annular shape and surrounding an interior reaction volume having a reaction gas inlet and a first reaction gas outlet, the second chamber having a second reaction gas outlet for directing reaction gas to a passenger in an aircraft, - an igniter for triggering the exothermic reaction of the reaction medium, - an exterior reaction volume being arranged within the first chamber between the reaction medium and the annular wall of the housing, and - a flow regulator arranged at the first reaction gas outlet and adapted to throttle the flow of reaction gas through the first reaction gas outlet based on an increase in temperature of the regulation device,
A cationic amphiphile with a mannose-mimicking acid head-group having the general formula A wherein each of R 1 and R 2 is independently hydrogen or a lipophilic moiety selected from (C 8 -C 24)-alkyl and mono-, di- and tri-unsaturated (C 8 -C 22)-alkenyl, provided R 1 and R 2 are not both hydrogen; R 3 is independently hydrogen or straight or branched (C 1 -C 5)-alkyl or a straight or branched hydroxyl- or amino-(C 1 -C 5)-alkyl functional group; X is a chlorine or bromine atom. each of R 1 and R 2 is independently hydrogen or a lipophilic moiety selected from (C 8 -C 24)-alkyl and mono-, di- and tri-unsaturated (C 8 -C 22)-alkenyl, provided R 1 and R 2 are not both hydrogen; R 3 is independently hydrogen or straight or branched (C 1 -C 5)-alkyl or a straight or branched hydroxyl- or amino-(C 1 -C 5)-alkyl functional group; X is a chlorine or bromine atom.
Hydraulic pressure amplifier arrangement comprising a supply port, a pressure outlet connected to the supply port via check valve means, a tank port, an intensifier section having a high pressure piston in a high pressure cylinder which is connected to the pressure outlet, a low pressure piston in a low pressure cylinder and connected to the high pressure piston, an intermediate space between the high pressure piston and the low pressure piston, a control valve controlling a pressure in the low pressure cylinder, and a feeder arrangement of the intensifier section including an input connection connected to the supply port and a return connection connected to the tank port, wherein the feeder arrangement (19, 20) comprises throttling means, wherein the throttling means have a variable throttling resistance and characterised in that the variable throttling resistance of the throttling means depends on at least one pressure in the pressure amplifier arrangement.
Embankment-securing device, comprising a vertically and horizontally extending grid construction which is to be arranged on the embankment side, said grid construction comprising a plastic or wire grid and a supporting grid fixed thereto, wherein the plastic or wire grid can be set up by means of the supporting grid with the formation of an upper and a lower horizontal leg (7, 6) and, connecting them, a vertically extending leg which is supported via the supporting grid, which can be supported with respect to the lower leg via one or more supporting elements, characterized in that the supporting grid is a plastic panel having a multiplicity of apertures.
Rotary lifting device comprising a rotary lifting shaft having a longitudinal axis, a linear motor for moving the rotary lifting shaft in the direction of its longitudinal axis, and a rotary motor for rotating the rotary lifting shaft about its longitudinal axis, wherein the rotary motor has a stator and a hollow rotor, through which the rotary lifting shaft extends and which is rotationally kinematically coupled to the rotary lifting shaft, and wherein the linear motor is arranged stationary relative to the rotary motor and has an armature having a motion axis along which the armature is supported so as to be linearly movable, wherein the armature is kinematically coupled to the rotary lifting shaft with respect to the movement of the rotary lifting shaft in the direction of its longitudinal axis at a first longitudinal end of the rotary lifting shaft, wherein the linear motor is arranged laterally beside the rotary motor, with the longitudinal axis of the rotary lifting shaft being arranged parallel to the axis of motion of the armature of the linear motor, characterized in that the rotor is hollow, and in that the rotary lifting device comprises a torque measurement assembly for determining the torque transmitted from the rotary motor to the rotary lifting shaft, wherein the torque measurement assembly has a hollow rotationally arranged measuring shaft which is arranged axially fixed and coaxial to the longitudinal axis of the rotary lifting shaft (30, wherein the rotary lifting shaft extends coaxially through the measuring shaft, wherein the measuring shaft at one end is rotationally kinematically coupled to the rotor of the rotary motor and at its other end is rotationally kinematically coupled to the rotary lifting shaft, and wherein the torque measurement assembly has a sensor assembly (68, 69) for determination of the torsion of the measuring shaft caused by the torque.