A system for interacting with a patient, comprising: a communication module configured to operate in at least three communication modes that comprises: unidirectional mode, in which the communication module outputs communication to the patient that does not require his/her response, responsive mode, in which the communication module outputs communication to the patient that requires his/her response, the responsive mode comprises questions to or requests from the patient, and open communication mode, in which the communication module allows the patient to proactively initiate communication with the system; a processing circuitry that comprises an input module configured to receive input data indicative of the patient sedation state, the processing circuitry is configured to i. determine the sedation state of the patient based on the input data; ii. triggering the communication module to operate in a selected communication mode in response to the determined sedation state; wherein the determination of the sedation state of the patient based on the input data comprises classifying the sedation state of the patient into one of at least three sedation levels, each level triggers a level-specific communication mode; wherein said classifying comprises scoring the sedation state of the patient, the score defines the sedation level, wherein three ranges of scores define the sedation levels, each range defines a different level; wherein the processing circuitry is configured to: - trigger the unidirectional mode upon determining a non-responsive sedation state of the patient; - trigger the responsive mode upon determining a low-level responsive sedation state of the patient; - trigger the open communication mode upon determining a high-level responsive sedation state of the patient. a communication module configured to operate in at least three communication modes that comprises: unidirectional mode, in which the communication module outputs communication to the patient that does not require his/her response, responsive mode, in which the communication module outputs communication to the patient that requires his/her response, the responsive mode comprises questions to or requests from the patient, and open communication mode, in which the communication module allows the patient to proactively initiate communication with the system; a processing circuitry that comprises an input module configured to receive input data indicative of the patient sedation state, the processing circuitry is configured to i. determine the sedation state of the patient based on the input data; ii. triggering the communication module to operate in a selected communication mode in response to the determined sedation state; i. determine the sedation state of the patient based on the input data; ii. triggering the communication module to operate in a selected communication mode in response to the determined sedation state; wherein the determination of the sedation state of the patient based on the input data comprises classifying the sedation state of the patient into one of at least three sedation levels, each level triggers a level-specific communication mode; wherein said classifying comprises scoring the sedation state of the patient, the score defines the sedation level, wherein three ranges of scores define the sedation levels, each range defines a different level; wherein the processing circuitry is configured to: - trigger the unidirectional mode upon determining a non-responsive sedation state of the patient; - trigger the responsive mode upon determining a low-level responsive sedation state of the patient; - trigger the open communication mode upon determining a high-level responsive sedation state of the patient. - trigger the unidirectional mode upon determining a non-responsive sedation state of the patient; - trigger the responsive mode upon determining a low-level responsive sedation state of the patient; - trigger the open communication mode upon determining a high-level responsive sedation state of the patient.