mhurhangee/ep-ind-claims huggingface dataset:
A liquid pharmaceutical composition suitable for administration by inhalation comprising a diluent and a suspension of particles of 9,10-dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one or a pharmaceutically acceptable salt thereof, wherein: the particles of RPL554 have a particle size distribution with a Dv50 (median particle size by volume) value of from 0.2 μm to 5 μm; and the composition comprises a phosphate buffer at a concentration of from 0 mg/mL to 5 mg/mL. the particles of RPL554 have a particle size distribution with a Dv50 (median particle size by volume) value of from 0.2 μm to 5 μm; and the composition comprises a phosphate buffer at a concentration of from 0 mg/mL to 5 mg/mL.
Method for forming a three-dimensional cell arrangement of biological cells, comprising the steps: - provision of the cells on a flexible substrate, and - deformation of the substrate, the deformation being produced by an attractive force (Fz) exerted by the cells on the substrate, wherein the substrate has a predetermined geometric arrangement of force action points, which are adapted for exerting the attractive force (F Z) by the cells on the substrate, characterized in that - the substrate has a predetermined geometric arrangement of deformation regions, each of which comprising at least one bending region and/or at least one stiffening region, and a flexibility, which is anisotropic and locally variable, and - the deformation comprises a directional deformation of the substrate with at least one predetermined main deformation direction, which is determined by the arrangement of the deformation regions and the force action points of the substrate, wherein - the deformation comprises a folding of the substrate such that the cell arrangement forms a three-dimensional pile of cells, and - the deformation regions are arranged such that the substrate deformed by the action of the attractive force (Fz) forms a cavity, a tubular shape and/or a spherical shape. - provision of the cells on a flexible substrate, and - deformation of the substrate, the deformation being produced by an attractive force (Fz) exerted by the cells on the substrate, wherein the substrate has a predetermined geometric arrangement of force action points, which are adapted for exerting the attractive force (F Z) by the cells on the substrate, - the substrate has a predetermined geometric arrangement of deformation regions, each of which comprising at least one bending region and/or at least one stiffening region, and a flexibility, which is anisotropic and locally variable, and - the deformation comprises a directional deformation of the substrate with at least one predetermined main deformation direction, which is determined by the arrangement of the deformation regions and the force action points of the substrate, wherein - the deformation comprises a folding of the substrate such that the cell arrangement forms a three-dimensional pile of cells, and - the deformation regions are arranged such that the substrate deformed by the action of the attractive force (Fz) forms a cavity, a tubular shape and/or a spherical shape.
A flat panel OLED device comprising: (a) a transparent deformable substrate having first and second sides and defining a predetermined illumination region and a non-illumination region; (b) a moisture-sensitive OLED disposed over the first side of the transparent substrate within the illumination region and means for applying electrical signals to the OLED which causes the OLED to produce light and heat; (c) a protective layer disposed over the OLED; and (d) a flexible encapsulating foil disposed over the protective layer, but not attached thereto, and which dissipates the heat and sealingly connected to the substrate in the non-illumination region, characterized by (e) a rigid chassis structure operatively associated with the transparent deformable substrate for providing rigidity to the transparent deformable substrate, the rigid chassis structure including a frame at the periphery of the transparent deformable substrate and cross-braces, wherein the cross-braces extend between inner lateral surfaces of the frame. (a) a transparent deformable substrate having first and second sides and defining a predetermined illumination region and a non-illumination region; (b) a moisture-sensitive OLED disposed over the first side of the transparent substrate within the illumination region and means for applying electrical signals to the OLED which causes the OLED to produce light and heat; (c) a protective layer disposed over the OLED; and (d) a flexible encapsulating foil disposed over the protective layer, but not attached thereto, and which dissipates the heat and sealingly connected to the substrate in the non-illumination region, characterized by (e) a rigid chassis structure operatively associated with the transparent deformable substrate for providing rigidity to the transparent deformable substrate, the rigid chassis structure including a frame at the periphery of the transparent deformable substrate and cross-braces, wherein the cross-braces extend between inner lateral surfaces of the frame.
A lubricant comprising a THF ester of the formula where R 1 and R 2 are selected independently from C 8 -C 12 alkyl, and further comprising - a base oil selected from mineral oils, polyalphaolefins, polymerized and interpolymerized olefins, alkyl naphthalenes, alkylene oxide polymers, silicone oils, phophate ester and carboxylic acid ester; and/or - a lubricant additive. - a base oil selected from mineral oils, polyalphaolefins, polymerized and interpolymerized olefins, alkyl naphthalenes, alkylene oxide polymers, silicone oils, phophate ester and carboxylic acid ester; and/or - a lubricant additive.
Medical instrument support device comprising a harness with a plate comprising belts for fixation on the chest of an operator, a first fastening element projecting directly from the plate in a direction perpendicular to the chest of said operator and a second complementary fastening element that can be attached to and detached from the first fastening element, an articulation element having a tubular and elongated shape and a first and a second end, in which it is fixed integrally and removably at its first end to the second complementary fastening element and supporting at its second end a housing angularly adjustable in space and which can be fixed in any angular position around an axis A by means of a clamp, the housing being configured to support the medical instrument and the articulation element being flexible so as to allow its deformation to assume a sinuous shape for a positioning of the housing in space, characterised in that said second complementary fastening element is able to rotate about an axis C substantially perpendicular to said plate.
A method of manufacturing a wind turbine blade, the method comprising: providing a mould for a shell of the wind turbine blade, the mould extending in a longitudinal direction from a root end to a tip end; providing a plurality of elongated root inserts; providing a root plate with a plurality of arcuately arranged connection points; at the connection points, connecting the root inserts to the root plate, such that the connected root inserts jointly form a contour of a portion of a root section of the wind turbine blade; and positioning the root plate relative to the mould in order to place the contour formed by the root inserts at least partially into the mould, wherein the method further comprises providing a spacer having a decreasing thickness, and wherein the connecting of the root inserts to the root plate comprises providing the spacer between the root inserts and the root plate. providing a mould for a shell of the wind turbine blade, the mould extending in a longitudinal direction from a root end to a tip end; providing a plurality of elongated root inserts; providing a root plate with a plurality of arcuately arranged connection points; at the connection points, connecting the root inserts to the root plate, such that the connected root inserts jointly form a contour of a portion of a root section of the wind turbine blade; and positioning the root plate relative to the mould in order to place the contour formed by the root inserts at least partially into the mould, wherein the method further comprises providing a spacer having a decreasing thickness, and wherein the connecting of the root inserts to the root plate comprises providing the spacer between the root inserts and the root plate.
A method of cooling the combustion gas in a heat exchanger of a steam generation plant, characterized in that the heat exchanger is adjustable via valves (34, 35) initially in the direct current and, if the effectiveness of the heat exchanger drops due to deposits, the combustion gas temperature is lowered by switching the heat exchanger from direct-current operation to counter-current operation.
A balanced plug assembly, comprising: a valve seat having a first opening and a second opening; a valve plug disposed on the end of a movable valve stem, the valve plug and the valve stem being movable relative to the valve seat, the valve plug interacting with the valve seat to selectively open or close the second opening; a diaphragm retainer, the diaphragm retainer being located between the valve plug and a balance chamber; and a sleeve extending away from the diaphragm retainer, the sleeve circumferentially surrounding the valve stem, a space being formed between the sleeve and the valve stem, the space forming a balancing passage, the plug assembly being further characterised by a plurality of openings circumferentially disposed about the sleeve, the plurality of openings directing fluid flow into openings at different locations within the sleeve; wherein the plurality of openings is located between the first opening and the second opening of the valve seat and upstream of a seating surface of the valve seat by more than 25% of a length of the valve seat. a valve seat having a first opening and a second opening; a valve plug disposed on the end of a movable valve stem, the valve plug and the valve stem being movable relative to the valve seat, the valve plug interacting with the valve seat to selectively open or close the second opening; a diaphragm retainer, the diaphragm retainer being located between the valve plug and a balance chamber; and a sleeve extending away from the diaphragm retainer, the sleeve circumferentially surrounding the valve stem, a space being formed between the sleeve and the valve stem, the space forming a balancing passage, the plug assembly being further characterised by a plurality of openings circumferentially disposed about the sleeve, the plurality of openings directing fluid flow into openings at different locations within the sleeve; wherein the plurality of openings is located between the first opening and the second opening of the valve seat and upstream of a seating surface of the valve seat by more than 25% of a length of the valve seat.
A micro-electromechanical system (1B to 1H) for actuation of a micro-cantilever ( 22, 22a, 22b, 42, 52, 60) by base excitation, the system comprising: a base substrate ( 18, 18a, 18b, 48, 48a); a micro-cantilever ( 22, 22a, 22b, 42, 52, 60) having a free end and a fixed end, the fixed end being fixed to the base substrate ( 18, 18a, 18b, 48, 48a); and one or more thermal actuators ( 20, 28, 32, 38, 44, 44a, 66, 68, 120) coupled to the micro-cantilever and to the base substrate ( 18, 18a, 18b, 48, 48a), wherein the one or more thermal actuators ( 20, 28, 32, 38, 44, 44a, 66, 68, 120) comprises an electrically conductive material to facilitate electro-thermal heating of the one or more thermal actuators ( 20, 28, 32, 38, 44, 44a, 66, 68, 120) to actuate the micro-cantilever ( 22, 22a, 22b, 42, 52, 60); wherein the system (1B to 1H) is configured to induce high frequency vibration of the free end of the micro-cantilever ( 22, 22a, 22b, 42, 52, 60) by base excitation caused by cyclic activation of the thermal actuator ( 20, 28, 32, 38, 44, 44a, 66, 68, 120). a base substrate ( 18, 18a, 18b, 48, 48a); a micro-cantilever ( 22, 22a, 22b, 42, 52, 60) having a free end and a fixed end, the fixed end being fixed to the base substrate ( 18, 18a, 18b, 48, 48a); and one or more thermal actuators ( 20, 28, 32, 38, 44, 44a, 66, 68, 120) coupled to the micro-cantilever and to the base substrate ( 18, 18a, 18b, 48, 48a), wherein the one or more thermal actuators ( 20, 28, 32, 38, 44, 44a, 66, 68, 120) comprises an electrically conductive material to facilitate electro-thermal heating of the one or more thermal actuators ( 20, 28, 32, 38, 44, 44a, 66, 68, 120) to actuate the micro-cantilever ( 22, 22a, 22b, 42, 52, 60); wherein the system (1B to 1H) is configured to induce high frequency vibration of the free end of the micro-cantilever ( 22, 22a, 22b, 42, 52, 60) by base excitation caused by cyclic activation of the thermal actuator ( 20, 28, 32, 38, 44, 44a, 66, 68, 120).
A method of operating an aircraft with multiple actuators, preferably multiple propulsion units, most preferably electrically powered propulsion units, comprising: i) monitoring an operational state of said multiple actuators; ii) when detecting a malfunctioning or failure of any one of said actuators, indicating said malfunctioning or failure to a pilot in command of the aircraft; iii) controlling a human machine interface of the aircraft to display and enable a limited choice of possible operating measures in connection with said malfunctioning or failure to the pilot in command; and iv) programming at least one control element (2ae, 2ae 1, 2ae 2) in association with said one actuator to perform said measures when actuated by the pilot in command; wherein in a first mode, step iii) is performed automatically upon detection of said malfunctioning or failure; characterized in that in a second mode, step iii) is performed upon selection of said one actuator by a user, e.g., by the pilot in command. i) monitoring an operational state of said multiple actuators; ii) when detecting a malfunctioning or failure of any one of said actuators, indicating said malfunctioning or failure to a pilot in command of the aircraft; iii) controlling a human machine interface of the aircraft to display and enable a limited choice of possible operating measures in connection with said malfunctioning or failure to the pilot in command; and iv) programming at least one control element (2ae, 2ae 1, 2ae 2) in association with said one actuator to perform said measures when actuated by the pilot in command; wherein in a first mode, step iii) is performed automatically upon detection of said malfunctioning or failure; characterized in that in a second mode, step iii) is performed upon selection of said one actuator by a user, e.g., by the pilot in command.
An industrial roll, comprising: a substantially cylindrical metallic core; a base layer that is adhered to and circumferentially overlies the core, the base layer having a thickness of between 1.5875 mm and 25.4 mm (0.0625 inch and 1 inch); a polymeric topstock layer that circumferentially overlies the base layer; and a hydrophobic and/or amphiphobic coating that circumferentially overlies the topstock layer, characterized in that the hydrophobic and/or amphiphobic coating has a contact angle greater than 120° for water and an organic fluid, the organic fluid being a hydrophobic compound comprising carbon and hydrogen, and in that the hydrophobic and/or amphiphobic coating comprises polytetrafluoroethylene (PFTE), a hydrophobic diatomaceous earth, and a matrix material comprising polyurethane in a ratio of about 1 part to about 50 parts by weight of PTFE against 100 parts by weight of polyurethane, and about 1 part to about 50 parts by weight of hydrophobic diatomaceous earth against 100 parts by weight of the polyurethane. a substantially cylindrical metallic core; a base layer that is adhered to and circumferentially overlies the core, the base layer having a thickness of between 1.5875 mm and 25.4 mm (0.0625 inch and 1 inch); a polymeric topstock layer that circumferentially overlies the base layer; and a hydrophobic and/or amphiphobic coating that circumferentially overlies the topstock layer, characterized in that the hydrophobic and/or amphiphobic coating has a contact angle greater than 120° for water and an organic fluid, the organic fluid being a hydrophobic compound comprising carbon and hydrogen, and in that the hydrophobic and/or amphiphobic coating comprises polytetrafluoroethylene (PFTE), a hydrophobic diatomaceous earth, and a matrix material comprising polyurethane in a ratio of about 1 part to about 50 parts by weight of PTFE against 100 parts by weight of polyurethane, and about 1 part to about 50 parts by weight of hydrophobic diatomaceous earth against 100 parts by weight of the polyurethane.
Holding device (34, 36, 38, 40, 164, 180, 192, 200, 204) for an implant, comprising a first connecting device for releasably connecting the holding device (34, 36, 38, 40, 164, 180, 192, 200, 204) and the implant, wherein the first connecting device is transferable from a first connecting position, an implant being connectable or connected to the holding device (34, 36, 38, 40, 164, 180, 192, 200, 204) in said position, into a first release position, the holding device (34, 36, 38, 40, 164, 180, 192, 200, 204) releasing the implant in said position, characterized by an indicating device which makes it possible to ascertain without any doubt that an implant held in the connecting position was connected to the holding device and has been released from the holding device.
A fluid supply apparatus, comprising: a primary fluid flow route that includes one or more primary flow control components (14, 15), an intervention shuttle valve having a primary inlet and a secondary inlet, and a destination; and a secondary fluid flow route that bypasses the primary flow control components and includes a modular removable block of one or more secondary flow control components, the intervention shuttle valve, and a selectively removable hose connecting the modular removable block of secondary flow control components to the secondary inlet of the intervention shuttle valve; and the destination, wherein the hose connects to the intervention shuttle valve and the modular removable block of secondary flow control components via a stab type connection, and wherein the modular removable block of secondary flow control components removably attaches to a modular block receiver that houses a stab type receiver connection for connection with the hose, and the modular removable block of secondary flow control components is removable from the modular block receiver without interrupting the primary flow route. a secondary fluid flow route that bypasses the primary flow control components and includes a modular removable block of one or more secondary flow control components, the intervention shuttle valve, and a selectively removable hose connecting the modular removable block of secondary flow control components to the secondary inlet of the intervention shuttle valve; and the destination, wherein the hose connects to the intervention shuttle valve and the modular removable block of secondary flow control components via a stab type connection, and wherein the modular removable block of secondary flow control components removably attaches to a modular block receiver that houses a stab type receiver connection for connection with the hose, and the modular removable block of secondary flow control components is removable from the modular block receiver without interrupting the primary flow route.
A method of minimizing transmit signal interference, comprising: receiving a signal; amplifying the received signal; mixing the received signal with an intermediate frequency signal to obtain a baseband modulated signal; filtering the baseband modulated signal in a first filter; dividing the first filtered baseband modulated signal among a main biquad filtering path and at least one auxiliary biquad filtering path; sending a first divided portion of the baseband modulated signal to the main path of a biquad filter, producing a first biquad filtered signal; sending a second divided portion of the baseband modulated signal to the auxiliary path of the biquad filter, producing a second biquad filtered signal; recombining the first biquad filtered signal with the second biquad filtered signal before a second stage of the biquad filter; and filtering the recombined biquad filtered signal in the second stage of the biquad filter. receiving a signal; amplifying the received signal; mixing the received signal with an intermediate frequency signal to obtain a baseband modulated signal; filtering the baseband modulated signal in a first filter; dividing the first filtered baseband modulated signal among a main biquad filtering path and at least one auxiliary biquad filtering path; sending a first divided portion of the baseband modulated signal to the main path of a biquad filter, producing a first biquad filtered signal; sending a second divided portion of the baseband modulated signal to the auxiliary path of the biquad filter, producing a second biquad filtered signal; recombining the first biquad filtered signal with the second biquad filtered signal before a second stage of the biquad filter; and filtering the recombined biquad filtered signal in the second stage of the biquad filter.
A method for obtaining a ceramic slurry for producing filaments for 3D FDM printing, characterised in that it comprises the stages of: a) preparing a suspension of a ceramic material in at least one alcohol and/or one C1-C8 ketone chain; b) adding a polysaccharide, a glycol or an ethanolamine as a gelling agent; c) adding a vinyl resin or polyalkyl carbonate as a binder; d) adding a phthalate, terpineol, polyolefin, thermoplastic or mixtures thereof as a plasticizing agent; and e) heating at a temperature between 60-150°C to obtain said ceramic slurry, further characterised in that the ratio of said gelling agent with respect to the said ceramic material is between 1:4 and 1:20 by weight; the ratio of said binder with respect to the said ceramic material is between 1:3 and 1:20 by weight; and the ratio of said plasticizing agent with respect to the said ceramic material is between 1:5 and 1:10 by weight, wherein the sequence of any of stages b) to e) may change order or may be simultaneous therebetween. a) preparing a suspension of a ceramic material in at least one alcohol and/or one C1-C8 ketone chain; b) adding a polysaccharide, a glycol or an ethanolamine as a gelling agent; c) adding a vinyl resin or polyalkyl carbonate as a binder; d) adding a phthalate, terpineol, polyolefin, thermoplastic or mixtures thereof as a plasticizing agent; and e) heating at a temperature between 60-150°C to obtain said ceramic slurry, further characterised in that the ratio of said gelling agent with respect to the said ceramic material is between 1:4 and 1:20 by weight; the ratio of said binder with respect to the said ceramic material is between 1:3 and 1:20 by weight; and the ratio of said plasticizing agent with respect to the said ceramic material is between 1:5 and 1:10 by weight, wherein the sequence of any of stages b) to e) may change order or may be simultaneous therebetween.