mhurhangee/ep-ind-claims huggingface dataset:
Apparatus for assistance in the implantation of a corneal prosthesis in a human eye, comprising a laser device for providing focussed, pulsed laser radiation, and a control program for the laser device, the control program being designed, when executed, to cause an incision figure to be produced in the tissue of the eye by means of the laser radiation, the incision figure allowing the corneal prosthesis to be inserted, the control program being designed such that the incision figure produced by execution of the control program comprises: a bed incision located entirely in the depth of the corneal material, and an annular incision, which extends from the bed incision at a location within the circumferential line of the latter, along its entire annular circumference, as far as the corneal anterior surface, wherein the bed incision and the annular incision define a corneal tissue region which is separated on all sides from surrounding corneal tissue, and wherein the control program is designed such that the annular incision is produced by the laser device proceeding, from the bed incision to the corneal anterior surface, with a plurality of superimposed laser radiation ring scans or a laser radiation spiral scan. a bed incision located entirely in the depth of the corneal material, and an annular incision, which extends from the bed incision at a location within the circumferential line of the latter, along its entire annular circumference, as far as the corneal anterior surface, wherein the bed incision and the annular incision define a corneal tissue region which is separated on all sides from surrounding corneal tissue, and wherein the control program is designed such that the annular incision is produced by the laser device proceeding, from the bed incision to the corneal anterior surface, with a plurality of superimposed laser radiation ring scans or a laser radiation spiral scan.
Extractor hood which has a control unit for controlling at least one functional unit of the extractor hood, a hood body and at least one flap pivotably fastened to the hood body, wherein the flap is mounted on the front end of the hood body so as to be pivotable about a horizontal pivot axis, characterised in that at least one sensor for detecting the state of the flap, namely a relative position of the flap in relation the hood body in the form of an inclination angle, is arranged on the flap, wherein the sensor is an acceleration sensor and is connected to the control unit of the extractor hood such that at least one functional unit of the extractor hood is controlled by the control unit on the basis of the detected state of the flap. wherein the flap is mounted on the front end of the hood body so as to be pivotable about a horizontal pivot axis, characterised in that at least one sensor for detecting the state of the flap, namely a relative position of the flap in relation the hood body in the form of an inclination angle, is arranged on the flap, wherein the sensor is an acceleration sensor and is connected to the control unit of the extractor hood such that at least one functional unit of the extractor hood is controlled by the control unit on the basis of the detected state of the flap.
An inline inspection tool body comprising: a plurality of composite magnetic field systems, each composite magnetic field system of the plurality containing two magnetic circuits (60A, 60B) arranged relative to one another to provide a resultant magnetic field at an angle α relative to an axial direction of the ILI tool body, where 0° <α < 90°, 0° being the axial direction, 90° being a transverse direction, the resultant magnetic field including a first magnetic field and a second magnetic field and being a vector addition of the first and second magnetic fields (1, 2); each of the two magnetic circuits including a first magnet and a second magnet spaced apart from each other, and arranged such that a pole (61N or 61S) of the first magnet is opposite in polarity to a spaced apart pole (61S or 61N) of the second magnet, each of the first and second magnets oriented at an angle different than the angle α of the resultant magnetic field; a first of the two magnetic circuits providing the first magnetic field in a first direction, a second of the two magnetic circuits providing the second magnetic field in a second direction different than that of the first magnetic field; wherein, one of the first and second directions is the axial direction and another one of the first and second directions is the transverse direction. a plurality of composite magnetic field systems, each composite magnetic field system of the plurality containing two magnetic circuits (60A, 60B) arranged relative to one another to provide a resultant magnetic field at an angle α relative to an axial direction of the ILI tool body, where 0° <α < 90°, 0° being the axial direction, 90° being a transverse direction, the resultant magnetic field including a first magnetic field and a second magnetic field and being a vector addition of the first and second magnetic fields (1, 2); each of the two magnetic circuits including a first magnet and a second magnet spaced apart from each other, and arranged such that a pole (61N or 61S) of the first magnet is opposite in polarity to a spaced apart pole (61S or 61N) of the second magnet, each of the first and second magnets oriented at an angle different than the angle α of the resultant magnetic field; a first of the two magnetic circuits providing the first magnetic field in a first direction, a second of the two magnetic circuits providing the second magnetic field in a second direction different than that of the first magnetic field; wherein, one of the first and second directions is the axial direction and another one of the first and second directions is the transverse direction.
A method of filling at least one fiber channel (14, 16) of a fiber box of a bundle individualizer with bristle packs (44, 46) of loose, parallel bristles, characterized by the following steps: providing an intermediate storage that is separate and spaced apart from the fiber box, providing a mechanical transport device for bristle packs (44, 46), removing a pack wrapping of a bristle pack (44, 46), subsequently inserting the bristle pack (44, 46) into one of a plurality of receptacles of an intermediate storage, in which one respective inserted bristle pack (44, 46) is laterally encompassed, and removing a bristle pack (44, 46) from one of the receptacles and transferring the bristle pack (44, 46) to the associated fiber channel (14, 16) and inserting the bristle pack (44, 46) into the fiber channel (14, 16), in each case by the transport device. providing an intermediate storage that is separate and spaced apart from the fiber box, providing a mechanical transport device for bristle packs (44, 46), removing a pack wrapping of a bristle pack (44, 46), subsequently inserting the bristle pack (44, 46) into one of a plurality of receptacles of an intermediate storage, in which one respective inserted bristle pack (44, 46) is laterally encompassed, and removing a bristle pack (44, 46) from one of the receptacles and transferring the bristle pack (44, 46) to the associated fiber channel (14, 16) and inserting the bristle pack (44, 46) into the fiber channel (14, 16), in each case by the transport device.
A method for determining one-way performance parameters when transmitting a packet in packet-switched communication subnetworks, wherein the packet is transmitted on a loop starting from a sender to a destination and back to the sender, thereby passing through a number of routers (ER origin, ER destination1, ER destination2, IR 11, IR 22), wherein a router may be an internal router or an edge router representing a transition between the communication subnetwork and a connected network or a termination of the communication subnetwork, and once the loop has been passed completely a measuring value is measured that is associated with the one-way performance parameter to be determined, which measuring value is assigned to said loop that has been passed as a whole; wherein all routes to be passed on the loop between any two particular routers within the loop are predefined for a packet already prior to its transmission such that in case of a number of n routes within the loop it is already possible to have recourse to one-way performance calibration values with respect to n-1 routes within the loop, which correspond to the one-way performance parameters to be determined, and the one-way performance parameter to be determined with respect to the remaining route is calculated in functional dependence of the performance measuring value measured for the entire loop that has been passed and of the one-way performance calibration values of the n-1 routes. wherein the packet is transmitted on a loop starting from a sender to a destination and back to the sender, thereby passing through a number of routers (ER origin, ER destination1, ER destination2, IR 11, IR 22), wherein a router may be an internal router or an edge router representing a transition between the communication subnetwork and a connected network or a termination of the communication subnetwork, and once the loop has been passed completely a measuring value is measured that is associated with the one-way performance parameter to be determined, which measuring value is assigned to said loop that has been passed as a whole; wherein all routes to be passed on the loop between any two particular routers within the loop are predefined for a packet already prior to its transmission such that in case of a number of n routes within the loop it is already possible to have recourse to one-way performance calibration values with respect to n-1 routes within the loop, which correspond to the one-way performance parameters to be determined, and the one-way performance parameter to be determined with respect to the remaining route is calculated in functional dependence of the performance measuring value measured for the entire loop that has been passed and of the one-way performance calibration values of the n-1 routes.
A voltage regulator comprising: switched mode regulator circuitry (301, 302, 304, 306) to generate a regulated voltage (V out), having series and shunt switching elements (301, 302); and voltage spike protection circuitry, arranged across the series and shunt switching elements at the input to the switched mode regulator circuitry for voltage-spike-protecting the switched mode regulator circuitry, comprising a dissipative element (R sp) and a charge-storage circuit (C sp); characterised in that: said switched mode regulator circuitry (301, 302, 304, 306) and said voltage spike circuitry are implemented by an integrated circuit in an integrated circuit package; said series and shunt switching elements (301, 302) of said switched mode regulator circuitry are subdivided into connected switching block segments (2120, 2130, 2140); and said charge-storage circuit (C sp) of said voltage-spike protection circuitry is subdivided into connected charge-storage circuit segments (2121, 2122) which are interleaved between said switching block segments. switched mode regulator circuitry (301, 302, 304, 306) to generate a regulated voltage (V out), having series and shunt switching elements (301, 302); and voltage spike protection circuitry, arranged across the series and shunt switching elements at the input to the switched mode regulator circuitry for voltage-spike-protecting the switched mode regulator circuitry, comprising a dissipative element (R sp) and a charge-storage circuit (C sp); characterised in that: said switched mode regulator circuitry (301, 302, 304, 306) and said voltage spike circuitry are implemented by an integrated circuit in an integrated circuit package; said series and shunt switching elements (301, 302) of said switched mode regulator circuitry are subdivided into connected switching block segments (2120, 2130, 2140); and said charge-storage circuit (C sp) of said voltage-spike protection circuitry is subdivided into connected charge-storage circuit segments (2121, 2122) which are interleaved between said switching block segments. said switched mode regulator circuitry (301, 302, 304, 306) and said voltage spike circuitry are implemented by an integrated circuit in an integrated circuit package; said series and shunt switching elements (301, 302) of said switched mode regulator circuitry are subdivided into connected switching block segments (2120, 2130, 2140); and said charge-storage circuit (C sp) of said voltage-spike protection circuitry is subdivided into connected charge-storage circuit segments (2121, 2122) which are interleaved between said switching block segments.
A composition that inhibits PAX2 expression and/or PAX2 activity, for use in the treatment of mammary intraepithelial neoplasia or low grade breast cancer in a subject, wherein said composition comprises: one or more ingredients selected from the group consisting of polynucleotides encoding a siRNA for PAX2 and polynucleotides that inhibit binding of PAX2 to DEFB1 promoter, wherein said polynucleotides that inhibit binding of PAX2 to DEFB1 promoter comprise a nucleotide sequence of CCTTG (SEQ ID NO:1), and wherein said MIN is characterized by an increased PAX2-to-DEFB1 expression ratio compared to the PAX2-to-DEFB1 expression ratio in normal breast tissue and an ER/PR status of ER + /PR +, and wherein said composition is to be used without adjuvant therapy, wherein said low grade breast cancer is characterized by an increased PAX2-to-DEFB 1 expression ratio compared to the PAX2-to-DEFB1 expression ratio in normal breast tissue and an ER/PR status of ER + /PR + or ER + /PR -, and wherein said composition is to be used with an adjuvant therapy selected from anti-Her2 or anti-AIB-1/SRC-3. one or more ingredients selected from the group consisting of polynucleotides encoding a siRNA for PAX2 and polynucleotides that inhibit binding of PAX2 to DEFB1 promoter, wherein said polynucleotides that inhibit binding of PAX2 to DEFB1 promoter comprise a nucleotide sequence of CCTTG (SEQ ID NO:1), and wherein said MIN is characterized by an increased PAX2-to-DEFB1 expression ratio compared to the PAX2-to-DEFB1 expression ratio in normal breast tissue and an ER/PR status of ER + /PR +, and wherein said composition is to be used without adjuvant therapy, wherein said low grade breast cancer is characterized by an increased PAX2-to-DEFB 1 expression ratio compared to the PAX2-to-DEFB1 expression ratio in normal breast tissue and an ER/PR status of ER + /PR + or ER + /PR -, and wherein said composition is to be used with an adjuvant therapy selected from anti-Her2 or anti-AIB-1/SRC-3.
A method for producing liquid hydrocarbon product comprising, disintegrating a hydrocarbon source comprising coal, wherein the disintegrating comprises comminution of the hydrocarbon source; pretreating the disintegrated hydrocarbon source, wherein the pretreating comprises a chemical pretreatment, a heat pretreatment, oxidation of the hydrocarbon source, or a combination thereof; solubilizing the disintegrated hydrocarbon source to form a slurry comprising a reactant molecule of the hydrocarbon source, wherein laccase or ammonium tartrate is used for solubilization; admixing a biochemical liquor into the slurry to form liquid hydrocarbons via enzyme assisted bond selective photo-fragmentation, wherein the biochemical liquor comprises at least one conversion enzyme configured to facilitate bond selective photo- fragmentation of said reactant molecule of the hydrocarbon source, wherein the at least one conversion enzyme is manganese peroxidase; separating the liquid hydrocarbons from the slurry, wherein contaminants remain in the slurry; and enriching the liquid hydrocarbons to form a liquid hydrocarbon product, wherein the enrichment of the liquid hydrocarbon product comprises further enzymatically-catalyzed reactions. disintegrating a hydrocarbon source comprising coal, wherein the disintegrating comprises comminution of the hydrocarbon source; pretreating the disintegrated hydrocarbon source, wherein the pretreating comprises a chemical pretreatment, a heat pretreatment, oxidation of the hydrocarbon source, or a combination thereof; solubilizing the disintegrated hydrocarbon source to form a slurry comprising a reactant molecule of the hydrocarbon source, wherein laccase or ammonium tartrate is used for solubilization; admixing a biochemical liquor into the slurry to form liquid hydrocarbons via enzyme assisted bond selective photo-fragmentation, wherein the biochemical liquor comprises at least one conversion enzyme configured to facilitate bond selective photo- fragmentation of said reactant molecule of the hydrocarbon source, wherein the at least one conversion enzyme is manganese peroxidase; separating the liquid hydrocarbons from the slurry, wherein contaminants remain in the slurry; and enriching the liquid hydrocarbons to form a liquid hydrocarbon product, wherein the enrichment of the liquid hydrocarbon product comprises further enzymatically-catalyzed reactions.
An apparatus for coupling radiation into and out of an optical fiber, the apparatus comprising: an optical element for coupling radiation into and out of the optical fiber; a radiation system operable to produce input radiation, the radiation system arranged such that the input radiation is at least partially received by the optical element; and a sensor system for receiving output radiation from the optical element and operable to generate a signal indicative of at least one characteristic of the output radiation; wherein the optical element, the radiation system and the sensor system are generally co axial and the radiation system and the sensor system are both disposed on the same side of the optical element, wherein the apparatus further comprises a central body, a first end body, and a second end body, and wherein the optical element and the sensor system is disposed in the central body, the first end body defines an optical fiber connection portion, and the radiation system is disposed in the second end body. an optical element for coupling radiation into and out of the optical fiber; a radiation system operable to produce input radiation, the radiation system arranged such that the input radiation is at least partially received by the optical element; and a sensor system for receiving output radiation from the optical element and operable to generate a signal indicative of at least one characteristic of the output radiation; wherein the optical element, the radiation system and the sensor system are generally co axial and the radiation system and the sensor system are both disposed on the same side of the optical element, wherein the apparatus further comprises a central body, a first end body, and a second end body, and wherein the optical element and the sensor system is disposed in the central body, the first end body defines an optical fiber connection portion, and the radiation system is disposed in the second end body.
A continuous process for the production of hydroxyethylpiperazine, the process comprising: feeding neat piperazine, recycled piperazine, and ethylene oxide to a reactor to form crude hydroxyethylpiperazine, the reactor being a continuous stirred tank reactor or a plug flow reactor; wherein a molar ratio of ethylene oxide to neat piperazine added to the reactor is greater than 1.10; and continuously feeding the crude hydroxyethylpiperazine from the reactor to a distillation system that includes at least one distillation column, the distillation system producing at least a recycled piperazine stream and a hydroxyethylpiperazine stream, the recycled piperazine stream including the recycled piperazine that is fed to the reactor to form the crude hydroxyethylpiperazine and the hydroxyethylpiperazine stream including at least 60 wt% of hydroxyethylpiperazine based on a total weight of the hydroxyethylpiperazine stream. feeding neat piperazine, recycled piperazine, and ethylene oxide to a reactor to form crude hydroxyethylpiperazine, the reactor being a continuous stirred tank reactor or a plug flow reactor; wherein a molar ratio of ethylene oxide to neat piperazine added to the reactor is greater than 1.10; and continuously feeding the crude hydroxyethylpiperazine from the reactor to a distillation system that includes at least one distillation column, the distillation system producing at least a recycled piperazine stream and a hydroxyethylpiperazine stream, the recycled piperazine stream including the recycled piperazine that is fed to the reactor to form the crude hydroxyethylpiperazine and the hydroxyethylpiperazine stream including at least 60 wt% of hydroxyethylpiperazine based on a total weight of the hydroxyethylpiperazine stream.
A surgical apparatus for positioning within a tissue tract accessing an underlying body cavity, which comprises: a flexible member defining an open proximal end, a closed distal end, and a passage extending there between; a string extending through the passage of the flexible member with a first end extending proximally beyond the open proximal end and a second end attached to the closed distal end; characterised by an anchor member attached to the open proximal end of the flexible member wherein the anchor member has a proximal flange, defines a passage for reception of objects therethrough, and is made from a material more rigid than that of the flexible member. a flexible member defining an open proximal end, a closed distal end, and a passage extending there between; a string extending through the passage of the flexible member with a first end extending proximally beyond the open proximal end and a second end attached to the closed distal end; characterised by an anchor member attached to the open proximal end of the flexible member wherein the anchor member has a proximal flange, defines a passage for reception of objects therethrough, and is made from a material more rigid than that of the flexible member.
An accelerator composition for the cure of epoxy resins with aromatic amines comprising (a) a metal complex with carboxylate ligands; and (b) a boron trifluoride amine complex or a boron trifluoride phenol complex, wherein the stoichiometric ratio of (a): (b) is in the range from 1: 3 to 3: 1. (a) a metal complex with carboxylate ligands; and (b) a boron trifluoride amine complex or a boron trifluoride phenol complex,