A machine for packaging products in powder, for example coffee powder, inside a container made of deformable material, comprising: - a compacting unit comprising a compacting chamber configured to receive a dose of product in powder at a first loading station, - a presser element configured to compact the dose of product in powder inside the compacting chamber in such a way as to obtain a compacted dose of product in powder, - a filling unit comprising at least a filling chamber configured to receive, at a first transfer station, the compacted dose of product in powder coming from the compacting unit and to provide a package being processed defined by a container made of deformable material filled with the compacted dose of product in powder, - sealing means configured to close and seal the package being processed, characterised in that it further comprises a vacuum chamber configured to receive the package being processed coming from the filling unit and to extract air from the package being processed, the sealing means being positioned in the vacuum chamber; and in that the compacting unit comprises a first drum rotating about a first axis of rotation and moves the compacting chamber from the first loading station to the first transfer station along a first feed path, the compacting chamber extending radially between an access opening radially external and the presser element, which is movable inside the compacting chamber in a radial direction between a loading position, wherein the presser element moves in a centripetal direction to allow entering the dose of product in powder in the compacting chamber, a compacting position, wherein the presser element acts in a centrifugal direction onto the dose of product in powder loaded in the compacting chamber, and a position of expulsion, wherein the presser element moving in the centrifugal direction expels the compacted dose of product in powder outside the compacting chamber. - a compacting unit comprising a compacting chamber configured to receive a dose of product in powder at a first loading station, - a presser element configured to compact the dose of product in powder inside the compacting chamber in such a way as to obtain a compacted dose of product in powder, - a filling unit comprising at least a filling chamber configured to receive, at a first transfer station, the compacted dose of product in powder coming from the compacting unit and to provide a package being processed defined by a container made of deformable material filled with the compacted dose of product in powder, - sealing means configured to close and seal the package being processed, characterised in that it further comprises a vacuum chamber configured to receive the package being processed coming from the filling unit and to extract air from the package being processed, the sealing means being positioned in the vacuum chamber; and in that the compacting unit comprises a first drum rotating about a first axis of rotation and moves the compacting chamber from the first loading station to the first transfer station along a first feed path, the compacting chamber extending radially between an access opening radially external and the presser element, which is movable inside the compacting chamber in a radial direction between a loading position, wherein the presser element moves in a centripetal direction to allow entering the dose of product in powder in the compacting chamber, a compacting position, wherein the presser element acts in a centrifugal direction onto the dose of product in powder loaded in the compacting chamber, and a position of expulsion, wherein the presser element moving in the centrifugal direction expels the compacted dose of product in powder outside the compacting chamber.