A computer executed method for calibrating a finite element model using measured data points, wherein the finite element model indicates a deformation of a physical object caused by the exertion of force to the physical object, the method comprising: generating a plurality of simulations of the physical object using the finite element model based on varying sets of input parameters, a simulation comprising a plurality of data points representing numerical solutions of the finite element model; calculating a mathematical operator for one of the plurality of simulations based on a metric for the data points of the one simulation, the mathematical operator defining a transformation that preserves the metric, the metric describing a distance between the individual data points of the one simulation; calculating eigenvectors of the mathematical operator; projecting the remaining simulations of the plurality of simulations into a space spanned by the eigenvectors; calculating a synthetic space point in the space by interpolating at least two space points corresponding to the simulations projected into the space; generating a synthetic simulation using an approximation for the finite element model based on the synthetic space point; and determining 2. the distance between the synthetic simulation and the measured data points, wherein either a) the transformation is an isometric transformation and the mathematical operator is a Laplace-Beltrami operator or b) the transformation is a non-linear transformation and the mathematical operator is a non-linear independent component analysis operator or a Fokker-Planck operator, and wherein calculating the synthetic space point in the space, generating the synthetic simulation and determining the distance between the synthetic simulation and the measured data points is carried out iteratively until the determined distance satisfies a quality criterior so as to enable calibration of the finite element model generating a plurality of simulations of the physical object using the finite element model based on varying sets of input parameters, a simulation comprising a plurality of data points representing numerical solutions of the finite element model; calculating a mathematical operator for one of the plurality of simulations based on a metric for the data points of the one simulation, the mathematical operator defining a transformation that preserves the metric, the metric describing a distance between the individual data points of the one simulation; calculating eigenvectors of the mathematical operator; projecting the remaining simulations of the plurality of simulations into a space spanned by the eigenvectors; calculating a synthetic space point in the space by interpolating at least two space points corresponding to the simulations projected into the space; generating a synthetic simulation using an approximation for the finite element model based on the synthetic space point; and determining 2. the distance between the synthetic simulation and the measured data points, wherein either a) the transformation is an isometric transformation and the mathematical operator is a Laplace-Beltrami operator or b) the transformation is a non-linear transformation and the mathematical operator is a non-linear independent component analysis operator or a Fokker-Planck operator, and wherein calculating the synthetic space point in the space, generating the synthetic simulation and determining the distance between the synthetic simulation and the measured data points is carried out iteratively until the determined distance satisfies a quality criterior so as to enable calibration of the finite element model