A system for imaging a body-part being perfused with a contrast agent, wherein the system includes: means for providing a sequence of input images offering a digital representation over time of the body-part, each input image including a plurality of input values each one indicative of a response to an interrogation signal of a corresponding location of the body-part possibly including the contrast agent, means for generating at least one filtered image from a sequence of a plurality of selected ones of the input images, wherein each filtered image includes a filtered value for each of a plurality of selected ones of the locations, the means for generating including: - first means for reducing a contribution of the contrast agent being substantially stationary at each selected location in the sequence of selected input images for a period of time equal to or shorter than a non-zero first threshold by removing intensity peaks of the input values of each selected location in the sequence of selected input images having durations equal to or shorter than the first threshold, and - second means for reducing a contribution of the contrast agent being substantially stationary at each selected location in the sequence of selected input images for a period of time equal to or longer than a second threshold higher than the first threshold by cumulating a variation of the input values of each selected location in the sequence of selected input images, thereby making each filtered value indicative of the contrast agent leaving the corresponding selected location after being substantially stationary at the corresponding selected location for a period of time comprised between the first threshold and the second threshold. means for providing a sequence of input images offering a digital representation over time of the body-part, each input image including a plurality of input values each one indicative of a response to an interrogation signal of a corresponding location of the body-part possibly including the contrast agent, means for generating at least one filtered image from a sequence of a plurality of selected ones of the input images, wherein each filtered image includes a filtered value for each of a plurality of selected ones of the locations, the means for generating including: - first means for reducing a contribution of the contrast agent being substantially stationary at each selected location in the sequence of selected input images for a period of time equal to or shorter than a non-zero first threshold by removing intensity peaks of the input values of each selected location in the sequence of selected input images having durations equal to or shorter than the first threshold, and - second means for reducing a contribution of the contrast agent being substantially stationary at each selected location in the sequence of selected input images for a period of time equal to or longer than a second threshold higher than the first threshold by cumulating a variation of the input values of each selected location in the sequence of selected input images, - first means for reducing a contribution of the contrast agent being substantially stationary at each selected location in the sequence of selected input images for a period of time equal to or shorter than a non-zero first threshold by removing intensity peaks of the input values of each selected location in the sequence of selected input images having durations equal to or shorter than the first threshold, and - second means for reducing a contribution of the contrast agent being substantially stationary at each selected location in the sequence of selected input images for a period of time equal to or longer than a second threshold higher than the first threshold by cumulating a variation of the input values of each selected location in the sequence of selected input images, thereby making each filtered value indicative of the contrast agent leaving the corresponding selected location after being substantially stationary at the corresponding selected location for a period of time comprised between the first threshold and the second threshold.