A compound of Formula or a pharmaceutically acceptable salt thereof wherein R 1 is selected from the group consisting of H, C 1-3 alkoxyl, C 1-3 alkyl, and halo; R 2 is C 1-5 alkyl optionally substituted with one or more substituents independently selected from the group consisting of OH, C 1-3 alkoxyl, halo, and CN or R 2 is -(CR a R b) n -Y, wherein n is 0, 1, or 2, each occurrence of R a and R b are independently H or methyl, Y is 1) a four to six-membered heterocyclyl optionally substituted with one or more substituents independently selected from the group consisting of C 1-3 alkyl, halo, OH, oxetanyl, C 1-3 haloalkyl, and morpholinyl; 2) C 3-6 cycloalkyl optionally substituted with one or more substituents independently selected from the group consisting of C 1-3 alkyl, halo, OH, or oxetanyl, C 1-3 haloalkyl, and morpholinyl, or 3) either of which is optionally substituted with one OH group; R 3 is selected from the group consisting of H, C 1-3 alkoxyl, C 1-3 alkyl, C 3-6 cycloalkyl, and halo; R 4 is CH or N; R 5 is H, CN or methyl; and R 6 is selected from the group consisting of C 1-3 alkoxy, and -O-CH 2 -C 3-6 cycloalkyl. R 1 is selected from the group consisting of H, C 1-3 alkoxyl, C 1-3 alkyl, and halo; R 2 is C 1-5 alkyl optionally substituted with one or more substituents independently selected from the group consisting of OH, C 1-3 alkoxyl, halo, and CN or R 2 is -(CR a R b) n -Y, wherein n is 0, 1, or 2, each occurrence of R a and R b are independently H or methyl, Y is 1) a four to six-membered heterocyclyl optionally substituted with one or more substituents independently selected from the group consisting of C 1-3 alkyl, halo, OH, oxetanyl, C 1-3 haloalkyl, and morpholinyl; 2) C 3-6 cycloalkyl optionally substituted with one or more substituents independently selected from the group consisting of C 1-3 alkyl, halo, OH, or oxetanyl, C 1-3 haloalkyl, and morpholinyl, or 3) either of which is optionally substituted with one OH group; n is 0, 1, or 2, each occurrence of R a and R b are independently H or methyl, Y is 1) a four to six-membered heterocyclyl optionally substituted with one or more substituents independently selected from the group consisting of C 1-3 alkyl, halo, OH, oxetanyl, C 1-3 haloalkyl, and morpholinyl; 2) C 3-6 cycloalkyl optionally substituted with one or more substituents independently selected from the group consisting of C 1-3 alkyl, halo, OH, or oxetanyl, C 1-3 haloalkyl, and morpholinyl, or 3) either of which is optionally substituted with one OH group; 1) a four to six-membered heterocyclyl optionally substituted with one or more substituents independently selected from the group consisting of C 1-3 alkyl, halo, OH, oxetanyl, C 1-3 haloalkyl, and morpholinyl; 2) C 3-6 cycloalkyl optionally substituted with one or more substituents independently selected from the group consisting of C 1-3 alkyl, halo, OH, or oxetanyl, C 1-3 haloalkyl, and morpholinyl, or 3) either of which is optionally substituted with one OH group; R 3 is selected from the group consisting of H, C 1-3 alkoxyl, C 1-3 alkyl, C 3-6 cycloalkyl, and halo; R 4 is CH or N; R 5 is H, CN or methyl; and R 6 is selected from the group consisting of C 1-3 alkoxy, and -O-CH 2 -C 3-6 cycloalkyl.