A fluid delivery system, comprising: a fluid administration device (110A,B) adapted to deliver a fluid volume, wherein the fluid volume comprises a volumetric amount of a contrast agent and a volumetric amount of a flush fluid, the fluid administration device (110A,B) comprising a first fluid delivery source operable to introduce a contrast agent to a patient and a second fluid delivery source operable to introduce a flush fluid to the patient independently from the first fluid delivery source wherein the first fluid delivery source is in operative connection with a first pressurizing mechanism and the second fluid delivery source is in operative connection with a second pressurizing mechanism; and a controller in communication with the fluid administration device (110A,B), wherein the controller comprises a processor and a non-transitory machine-readable storage medium, wherein the non-transitory machine-readable storage medium comprises instructions that, when executed by the processor, enable the fluid administration device (110A,B) to: deliver the fluid volume at a preselected total volumetric flowrate (FR tot) during a first duration of a fluid delivery procedure; controllably vary the volumetric amount of the contrast agent in the fluid volume during the first duration of the fluid delivery procedure, wherein the volumetric amount of the contrast agent is both controllably decreased and controllably increased during the first duration; and controllably increasing and controllably decreasing the volumetric amount of the flush fluid in the fluid volume in a manner that is complementary to the variation in the volumetric amount of the contrast agent while the volumetric amount of the contrast agent is being controllably decreased and controllably increased so as to substantially maintain the preselected total volumetric flowrate (FR tot) throughout the first duration of the fluid delivery procedure. a fluid administration device (110A,B) adapted to deliver a fluid volume, wherein the fluid volume comprises a volumetric amount of a contrast agent and a volumetric amount of a flush fluid, the fluid administration device (110A,B) comprising a first fluid delivery source operable to introduce a contrast agent to a patient and a second fluid delivery source operable to introduce a flush fluid to the patient independently from the first fluid delivery source wherein the first fluid delivery source is in operative connection with a first pressurizing mechanism and the second fluid delivery source is in operative connection with a second pressurizing mechanism; and a controller in communication with the fluid administration device (110A,B), wherein the controller comprises a processor and a non-transitory machine-readable storage medium, wherein the non-transitory machine-readable storage medium comprises instructions that, when executed by the processor, enable the fluid administration device (110A,B) to: deliver the fluid volume at a preselected total volumetric flowrate (FR tot) during a first duration of a fluid delivery procedure; controllably vary the volumetric amount of the contrast agent in the fluid volume during the first duration of the fluid delivery procedure, wherein the volumetric amount of the contrast agent is both controllably decreased and controllably increased during the first duration; and controllably increasing and controllably decreasing the volumetric amount of the flush fluid in the fluid volume in a manner that is complementary to the variation in the volumetric amount of the contrast agent while the volumetric amount of the contrast agent is being controllably decreased and controllably increased so as to substantially maintain the preselected total volumetric flowrate (FR tot) throughout the first duration of the fluid delivery procedure. deliver the fluid volume at a preselected total volumetric flowrate (FR tot) during a first duration of a fluid delivery procedure; controllably vary the volumetric amount of the contrast agent in the fluid volume during the first duration of the fluid delivery procedure, wherein the volumetric amount of the contrast agent is both controllably decreased and controllably increased during the first duration; and controllably increasing and controllably decreasing the volumetric amount of the flush fluid in the fluid volume in a manner that is complementary to the variation in the volumetric amount of the contrast agent while the volumetric amount of the contrast agent is being controllably decreased and controllably increased so as to substantially maintain the preselected total volumetric flowrate (FR tot) throughout the first duration of the fluid delivery procedure.