mhurhangee/ep-ind-claims huggingface dataset:
A handpiece for ocular surgery, comprising: a proximal portion having at least inlet ports for irrigation tubing and aspiration tubing, and providing an irrigation fluidic pathway extending therethrough from the irrigation tubing inlet port, and providing an aspiration fluidic pathway extending therethrough from the aspiration inlet port; a distal portion terminating in an emulsifying tip, and providing an aspiration pathway terminating in an aspiration output, and at least one irrigation pathway terminating in at least one irrigation output; and characterized by a swivel ball provided at a base of the proximal portion and having a first opening to the irrigation fluidic pathway, and a second opening to the aspiration fluidic pathway, which seats within a socket cup provided at an upper end of the distal portion, wherein the socket cup provides an irrigation opening that fluidically connects the first opening and the at least one irrigation pathway, and an aspiration opening that fluidically connects the second opening and the aspiration pathway; wherein the swivel ball is capable of both an axial angular rotation and a circumferential rotation within the socket cup while maintaining continuous fluidic communication from the irrigation tubing inlet port to the at least one irrigation output, and from the aspiration tubing inlet port to the aspiration output. a proximal portion having at least inlet ports for irrigation tubing and aspiration tubing, and providing an irrigation fluidic pathway extending therethrough from the irrigation tubing inlet port, and providing an aspiration fluidic pathway extending therethrough from the aspiration inlet port; a distal portion terminating in an emulsifying tip, and providing an aspiration pathway terminating in an aspiration output, and at least one irrigation pathway terminating in at least one irrigation output; and characterized by a swivel ball provided at a base of the proximal portion and having a first opening to the irrigation fluidic pathway, and a second opening to the aspiration fluidic pathway, which seats within a socket cup provided at an upper end of the distal portion, wherein the socket cup provides an irrigation opening that fluidically connects the first opening and the at least one irrigation pathway, and an aspiration opening that fluidically connects the second opening and the aspiration pathway; wherein the swivel ball is capable of both an axial angular rotation and a circumferential rotation within the socket cup while maintaining continuous fluidic communication from the irrigation tubing inlet port to the at least one irrigation output, and from the aspiration tubing inlet port to the aspiration output.
A therapeutic polypeptide comprising a cell wall targeting domain of a bacteriolysin fused to an immune function mediating component (IFMC) through a peptide linker, wherein the bacteriolysin is a bacteriocin selected from the group consisting of: Lysostaphin; Bacteriocin AS-48; Bacteriocin ColE9; adherence binding domain peptides of the pilin protein; an E-colicin; Autolysin; and the FyuA binding domain of pesticin fused to the N-terminus of T4 lysozyme, or wherein the bacteriolysin is a phage-encoded lysin selected from the group consisting of: Phage phiKZ gp144 lysin; φNM3 lysin; φ11 lysin; φ68, P17 lysin; φB30 lysin; φK, LysK lysin; φ MR11, MV-L lysin; φSs2, PlySs2bacteriophage lysin; OBPgp279 endolysin; PVP-SE1gp146 lysin; E201φ2-1gp229 lysin; Endolysin PlyL; Endolysin PlyG; LambdaSa2 cpl-7 lysin; lysogenic bacteriophage SM1 lysin; Endolysin CD27L; and mycobacteriophage Ms6 lysin, wherein the IFMC comprises an antibody or antigen-binding fragment thereof to a bacterial toxin or toxoid released by a bacterial target, wherein the antibody or antigen-binding fragment thereof lacks the ability to recognize a bacterial cell wall, and wherein the cell wall targeting domain of the therapeutic polypeptide targets the IFMC to the bacterial target. wherein the bacteriolysin is a bacteriocin selected from the group consisting of: Lysostaphin; Bacteriocin AS-48; Bacteriocin ColE9; adherence binding domain peptides of the pilin protein; an E-colicin; Autolysin; and the FyuA binding domain of pesticin fused to the N-terminus of T4 lysozyme, or wherein the bacteriolysin is a phage-encoded lysin selected from the group consisting of: Phage phiKZ gp144 lysin; φNM3 lysin; φ11 lysin; φ68, P17 lysin; φB30 lysin; φK, LysK lysin; φ MR11, MV-L lysin; φSs2, PlySs2bacteriophage lysin; OBPgp279 endolysin; PVP-SE1gp146 lysin; E201φ2-1gp229 lysin; Endolysin PlyL; Endolysin PlyG; LambdaSa2 cpl-7 lysin; lysogenic bacteriophage SM1 lysin; Endolysin CD27L; and mycobacteriophage Ms6 lysin, wherein the IFMC comprises an antibody or antigen-binding fragment thereof to a bacterial toxin or toxoid released by a bacterial target, wherein the antibody or antigen-binding fragment thereof lacks the ability to recognize a bacterial cell wall, and wherein the cell wall targeting domain of the therapeutic polypeptide targets the IFMC to the bacterial target.
Rotor hub arrangement for an electric fan, in particular for a radiator fan of a motor vehicle, comprising - a hub cup which rotates during operation and comprises air outlet guides on its inside, which are arranged and formed in such way that they guide and accelerate cooling air, - a return cup arranged inside the hub cup, said return cup comprising air passage openings, which form continuous air outlets together with the air outlet guides of the hub cup for a cooling air stream from the pressure side to the vacuum side of the fan, characterized in that the air outlet guides in the hub cup each form a substantially radially oriented air outlet, which is embedded into a depression in a base of the hub cup and/or is formed in a recess in the circumferential wall of the hub cup, so that the cooling air stream is directed outwards in the radial direction. - a hub cup which rotates during operation and comprises air outlet guides on its inside, which are arranged and formed in such way that they guide and accelerate cooling air, - a return cup arranged inside the hub cup, said return cup comprising air passage openings, which form continuous air outlets together with the air outlet guides of the hub cup for a cooling air stream from the pressure side to the vacuum side of the fan,
Drive unit for a door leaf, comprising an electric drive, wherein the rotary motion of the electric drive acts on a spindle nut and a threaded spindle engages into the spindle nut, wherein said threaded spindle can be connected to the door leaf, characterised in that the electric drive together with the spindle nut can be connected to a car body of a rail vehicle by means of a spherical bearing.
An endosteal horizontally placeable non-crestal dental implant system comprising: a. at least one dental implant having a proximal end, a distal end, an internal architecture, and an outside region having a helical thread extending along the outside region between the proximal end and the distal end, the dental implant configured to be implanted horizontally or near horizontally by way of a non-crestal approach into: a mandible having a first side and a buccal side, the first side a lingual side; or a maxilla having a first side and a buccal side, the first side a palatal side, the dental implant configured to be inserted from either the buccal side towards the first side or from the first side towards the buccal side at an angle; and b. at least one dental implant abutment having a proximal end for attaching to the dental implant and a distal end configured for attachment of a dental prosthesis, characterised in that the proximal end and/or the distal end of the at least one dental implant have an angular configuration wherein the at least one dental implant abutment is positionable at an angle neither parallel with nor perpendicular to the at least one dental implant. a. at least one dental implant having a proximal end, a distal end, an internal architecture, and an outside region having a helical thread extending along the outside region between the proximal end and the distal end, the dental implant configured to be implanted horizontally or near horizontally by way of a non-crestal approach into: a mandible having a first side and a buccal side, the first side a lingual side; or a maxilla having a first side and a buccal side, the first side a palatal side, the dental implant configured to be inserted from either the buccal side towards the first side or from the first side towards the buccal side at an angle; and a mandible having a first side and a buccal side, the first side a lingual side; or a maxilla having a first side and a buccal side, the first side a palatal side, the dental implant configured to be inserted from either the buccal side towards the first side or from the first side towards the buccal side at an angle; and b. at least one dental implant abutment having a proximal end for attaching to the dental implant and a distal end configured for attachment of a dental prosthesis,
A grommet assembly, comprising: a first shell (80;82); a second shell (76;78) spaced from the first shell (80;82) and including a hole having a centerline; and a grommet including a tubular portion projecting into the hole and defining a bore along a centerline through the first (80;82) and second (76;78) shells, wherein at least one of the first (80;82) and second (76;78) shells are configured for relative movement along a thermal displacement path such that the centerlines (122,134) of the hole of the second shell (76;78) and the bore of the grommet move relative to one another along the thermal displacement path; characterised in that the grommet includes a truncated flange portion disposed between the first (80;82) and second (76;78) shells and projecting outward from the tubular portion. a first shell (80;82); a second shell (76;78) spaced from the first shell (80;82) and including a hole having a centerline; and a grommet including a tubular portion projecting into the hole and defining a bore along a centerline through the first (80;82) and second (76;78) shells, wherein at least one of the first (80;82) and second (76;78) shells are configured for relative movement along a thermal displacement path such that the centerlines (122,134) of the hole of the second shell (76;78) and the bore of the grommet move relative to one another along the thermal displacement path; characterised in that the grommet includes a truncated flange portion disposed between the first (80;82) and second (76;78) shells and projecting outward from the tubular portion.
An injection device for injecting automatically a medicament, the injection device comprising a force measurement unit configured to measure an injection force, wherein the injection device further comprises: - a first occlusion detector configured to take force measurements (Fn) at a first measurement rate, and to generate a first occlusion indicating signal based on a set of force measurements (Fn) taken at the first measurement rate; - a second occlusion detector configured to take force measurements (Fn) at a second measurement rate, lower than the first measurement rate, and to generate a second occlusion indicating signal based on a set of force measurements (Fn) taken at the second measurement rate; and - an alarm generator configured to generate an occlusion alarm signal in cases where the first occlusion indicating signal is generated by the first occlusion detector or the second occlusion indicating signal is generated by the second occlusion detector. - a first occlusion detector configured to take force measurements (Fn) at a first measurement rate, and to generate a first occlusion indicating signal based on a set of force measurements (Fn) taken at the first measurement rate; - a second occlusion detector configured to take force measurements (Fn) at a second measurement rate, lower than the first measurement rate, and to generate a second occlusion indicating signal based on a set of force measurements (Fn) taken at the second measurement rate; and - an alarm generator configured to generate an occlusion alarm signal in cases where the first occlusion indicating signal is generated by the first occlusion detector or the second occlusion indicating signal is generated by the second occlusion detector.
Turbine (1;1';1";1"') for an internal combustion engine, - having a turbine housing (2;2';2";2"') comprising an inlet opening and an outlet opening (3, 4; 3'), - having a housing interior space surrounded by the turbine housing (2;2';2";2"') and adapted to be subjected to a through-flow of exhaust gas from the internal combustion engine, - having a turbine rotor rotatably mounted in the turbine housing (2;2';2";2"') about an axis of rotation defining an axial direction, the turbine rotor separating the housing interior space into a high-pressure region (7, 7") fluidically connected to the inlet opening (3; 3') and a low-pressure region (8, 8"') fluidically connected to the outlet opening, - having a measuring chamber (9; 9';9"; 9"') provided in the turbine housing (2;2';2";2"'), in which an exhaust gas sensor (10; 10'; 10"; 10"') for determining at least part of a gas component of the exhaust gas carried in the turbine housing (2;2';2";2"') is at least partially arranged, - wherein feed lines (11; 11"), each having a feed opening (12;12';12";12"'), and discharge lines (13; 13"), each having a discharge opening (14; 14'; 14"; 14"'), for respectively feeding or discharging exhaust gas into or out of the measuring chamber (9; 9';9"; 9"') are formed in the turbine housing (2;2';2";2"') integrally with said turbine housing (2;2';2";2"'), characterised in that a region of the turbine housing surrounding the high-pressure region is partially formed as a volute (16; 16") in which the feed opening (12; 12') of the feed line and the discharge opening (14; 14') of the discharge line (13; 13') are arranged. - having a turbine housing (2;2';2";2"') comprising an inlet opening and an outlet opening (3, 4; 3'), - having a housing interior space surrounded by the turbine housing (2;2';2";2"') and adapted to be subjected to a through-flow of exhaust gas from the internal combustion engine, - having a turbine rotor rotatably mounted in the turbine housing (2;2';2";2"') about an axis of rotation defining an axial direction, the turbine rotor separating the housing interior space into a high-pressure region (7, 7") fluidically connected to the inlet opening (3; 3') and a low-pressure region (8, 8"') fluidically connected to the outlet opening, - having a measuring chamber (9; 9';9"; 9"') provided in the turbine housing (2;2';2";2"'), in which an exhaust gas sensor (10; 10'; 10"; 10"') for determining at least part of a gas component of the exhaust gas carried in the turbine housing (2;2';2";2"') is at least partially arranged, - wherein feed lines (11; 11"), each having a feed opening (12;12';12";12"'), and discharge lines (13; 13"), each having a discharge opening (14; 14'; 14"; 14"'), for respectively feeding or discharging exhaust gas into or out of the measuring chamber (9; 9';9"; 9"') are formed in the turbine housing (2;2';2";2"') integrally with said turbine housing (2;2';2";2"'), characterised in that a region of the turbine housing surrounding the high-pressure region is partially formed as a volute (16; 16") in which the feed opening (12; 12') of the feed line and the discharge opening (14; 14') of the discharge line (13; 13') are arranged.
A delamination resistant pharmaceutical container comprising a glass composition comprising: SiO 2 in an amount greater than or equal to 72 mol.% and less than or equal to 78 mol.%; from 3.0 mol.% to 13 mol.% alkaline earth oxide comprising both MgO and CaO, wherein CaO is present in an amount from 0.1 mol.% to 1.0 mol.%, and a ratio (CaO (mol.%)/(CaO (mol.%)+MgO (mol.%))) is less than or equal to 0.5; X mol.% Al 2 O 3, wherein X is greater than or equal to 5 mol.% and less than or equal to 7 mol.%; Y mol.% alkali oxide, wherein the alkali oxide comprises Na 2 O in an amount greater than 8 mol.%; a ratio of a concentration of B 2 O 3 (mol.%) in the glass container to (Y mol.% - X mol.%) is less than or equal to 0.3; and a ratio of Y:X is greater than 1 and less than or equal to 2; said container containing a pharmaceutical composition comprising an active pharmaceutical ingredient selected from the group consisting of insulin, an insulin analog, a human insulin isophane suspension, insulin aspart injection, a mixture of 70% human insulin isophane and 30% regular insulin, an insulin zinc suspension, a mixture of insulin aspart and insulin aspart protamine, and insulin detemir. SiO 2 in an amount greater than or equal to 72 mol.% and less than or equal to 78 mol.%; from 3.0 mol.% to 13 mol.% alkaline earth oxide comprising both MgO and CaO, wherein CaO is present in an amount from 0.1 mol.% to 1.0 mol.%, and a ratio (CaO (mol.%)/(CaO (mol.%)+MgO (mol.%))) is less than or equal to 0.5; X mol.% Al 2 O 3, wherein X is greater than or equal to 5 mol.% and less than or equal to 7 mol.%; Y mol.% alkali oxide, wherein the alkali oxide comprises Na 2 O in an amount greater than 8 mol.%; a ratio of a concentration of B 2 O 3 (mol.%) in the glass container to (Y mol.% - X mol.%) is less than or equal to 0.3; and a ratio of Y:X is greater than 1 and less than or equal to 2;
A composition for lightening hyperpigmented skin comprising 1% to 20% by weight of arbutin as a carbohydrate-based melanin inhibiting agent incorporated into an aminoglycan polymer gel, and at least one cosmetically acceptable ingredient, wherein the aminoglycan polymer is hyaluronic acid sodium salt having a molecular weight ranging from 15000 to 30000 daltons.
A set of laminates including an outer laminate and an inner laminate, wherein the outer laminate includes a transparent polymeric support having on one side of the support a colour laser markable layer containing an infrared dye having an absorption maximum in the infrared region λ max (IR-3); wherein the inner laminate includes a transparent polymeric support having on one side of the transparent polymeric support a colour laser markable layer containing an infrared dye having an absorption maximum in the infrared region λ max (IR-2) and on the opposite side of the transparent polymeric support a colour laser markable layer containing an infrared dye having an absorption maximum in the infrared region λ max (IR-1); and where in the conditions a) and b) are fulfilled: a) λ max (IR-1) > λ max (IR-2) > λ max (IR-3); and b) λ max (IR-1) > 1100 nm and λ max (IR-3) < 1000 nm; wherein the three colour laser markable layers each include a different leuco dye for forming a colour having an absorption maximum λ max (VIS-1), λ max (VIS-2), respectively λ max (VIS-3) in the visible spectrum of 400 nm to 700 nm, wherein all the relations a) to c) are fulfilled: a) 400 nm < λ max (VIS-1) < 500 nm; b) 500 nm < λ max (VIS-2) < 600 nm; and c) 600 nm < λ max (VIS-3) < 700 nm. a) λ max (IR-1) > λ max (IR-2) > λ max (IR-3); and b) λ max (IR-1) > 1100 nm and λ max (IR-3) < 1000 nm; a) 400 nm < λ max (VIS-1) < 500 nm; b) 500 nm < λ max (VIS-2) < 600 nm; and c) 600 nm < λ max (VIS-3) < 700 nm.
A turbine comprising: a row of turbine rotor blades extending radially outwardly from a rotor disk; a turbine shroud surrounding said blades; a shroud hanger surrounding and supporting said shroud, and including an inlet extending therethrough; a shroud support surrounding and supporting said hanger; an outer casing surrounding and supporting said shroud support; an impingement baffle disposed between said shroud and hanger, and including a perforate plate spaced radially therebetween; and an imperforate deflector spaced from said plate in alignment with said hanger inlet for laterally deflecting air discharged therefrom around said deflector to said perforate plate, characterised in that the deflector is an imperforate plate being smaller than the perforate plate and being spaced from said perforate plate in line-of-sight alignment with said hanger inlet. a row of turbine rotor blades extending radially outwardly from a rotor disk; a turbine shroud surrounding said blades; a shroud hanger surrounding and supporting said shroud, and including an inlet extending therethrough; a shroud support surrounding and supporting said hanger; an outer casing surrounding and supporting said shroud support; an impingement baffle disposed between said shroud and hanger, and including a perforate plate spaced radially therebetween; and an imperforate deflector spaced from said plate in alignment with said hanger inlet for laterally deflecting air discharged therefrom around said deflector to said perforate plate, characterised in that the deflector is an imperforate plate being smaller than the perforate plate and being spaced from said perforate plate in line-of-sight alignment with said hanger inlet.
A vehicle control method in which, when a drive source stop condition is established while a vehicle is traveling, a sailing stop control is executed in which a drive source of the vehicle is stopped, an engaging element provided between the drive source and a drive wheel is released, and the vehicle travels under inertia, the vehicle control method comprising: acquiring information on a status of a road on which the host vehicle will travel; predicting whether there is a section on a route where the sailing stop control can be executed based on the information; upon predicting that the section is present where the sailing stop control can be executed, estimating a power shortage amount, which is a shortage in an amount of power during the sailing stop control, based on the information; and charging a battery with power required to cover the power shortage amount prior to starting the sailing stop control, wherein the power shortage amount is estimated as being larger when autonomous driving is performed in the section where the sailing stop control is executed as compared to when driver-enabled driving is performed in the section and the information includes route information, map information acquired by a navigation system, a travel history of the vehicle, and other information acquired through road-to-vehicle communication and/or vehicle-to-vehicle communication. acquiring information on a status of a road on which the host vehicle will travel; predicting whether there is a section on a route where the sailing stop control can be executed based on the information; upon predicting that the section is present where the sailing stop control can be executed, estimating a power shortage amount, which is a shortage in an amount of power during the sailing stop control, based on the information; and charging a battery with power required to cover the power shortage amount prior to starting the sailing stop control, wherein the power shortage amount is estimated as being larger when autonomous driving is performed in the section where the sailing stop control is executed as compared to when driver-enabled driving is performed in the section and the information includes route information, map information acquired by a navigation system, a travel history of the vehicle, and other information acquired through road-to-vehicle communication and/or vehicle-to-vehicle communication.