mhurhangee/ep-ind-claims huggingface dataset:
A genetically modified rodent whose genome comprises a humanized cluster of differentiation 274 gene encoding a humanized Programmed death-ligand 1 (PD-L1) polypeptide at an endogenous CD274 locus, wherein said humanized CD274 gene comprises a nucleic acid sequence encoding the extracellular sequence of a human PD-L1 polypeptide, operably linked to (i) a nucleic acid sequence encoding the intracellular sequence and the transmembrane sequence of an endogenous rodent PD-L1 polypeptide, and (ii) an endogenous rodent CD274 promoter; and wherein said rodent expresses the humanized PD-L1 polypeptide on the surface of a cell of said rodent. (i) a nucleic acid sequence encoding the intracellular sequence and the transmembrane sequence of an endogenous rodent PD-L1 polypeptide, and (ii) an endogenous rodent CD274 promoter;
Production method for a pendulum arrangement of a pendulum laser apparatus, at least including • a method step, in which a universal joint of a pendulum of the pendulum arrangement is produced by means of plastic injection moulding, by forming two orthogonal shafts (50a, 50b) that are provided with rolling bearings (36a, 36b), • a second method step, in which an optics carrier of the pendulum of the pendulum arrangement is produced integrally, in particular in a form-fitting and force-fitting manner, with the universal joint, by means of plastic injection moulding, wherein the universal joint is produced integrally with the rolling bearings (36a, 36b), in particular in a form-fitting and force-fitting manner, by overmoulding at least two rolling bearings (36a, 36b) defining in each case one shaft (50a, 50b) of the universal joint. • a method step, in which a universal joint of a pendulum of the pendulum arrangement is produced by means of plastic injection moulding, by forming two orthogonal shafts (50a, 50b) that are provided with rolling bearings (36a, 36b), • a second method step, in which an optics carrier of the pendulum of the pendulum arrangement is produced integrally, in particular in a form-fitting and force-fitting manner, with the universal joint, by means of plastic injection moulding,
A holder-furnished semiconductor laser comprising a semiconductor laser and a laser holder, the semiconductor laser having a metal frame part in which a semiconductor laser chip is mounted on one surface, and a resin part provided so as to surround the semiconductor laser chip, the laser holder having an insertion part into which the semiconductor laser is inserted and holding the semiconductor laser, wherein the laser holder is provided with a plate-shaped part in which an insertion port into which the semiconductor laser is inserted is formed, and a projecting part provided so as to protrude from the plate-shaped part and having a space that forms, along with the insertion port, the insertion part, and characterized in that the insertion part is provided with an aperture part (103a, 103b) that is provided in a side surface of the projecting part and that allows the resin part of the semiconductor laser inserted into the insertion part to be pushed from the exterior, and a wall surface part against which a reverse surface of the one surface of the metal frame part is pressed in a case where the resin part is pushed from the exterior.
A production method of a metal pipe, comprising the steps of: straightening a bend of a metal pipe by a straightening machine; characterized in that the production method further comprises cutting off both pipe end portions (70A, 70B) of the metal pipe whose bend has been straightened; and conveying a plurality of the metal pipes whose both pipe end portions (70A, 70B) have been cut off, to a quenching apparatus, and quenching the metal pipes by cooling after heating by induction heating the metal pipes in the quenching apparatus. straightening a bend of a metal pipe by a straightening machine; characterized in that the production method further comprises cutting off both pipe end portions (70A, 70B) of the metal pipe whose bend has been straightened; and conveying a plurality of the metal pipes whose both pipe end portions (70A, 70B) have been cut off, to a quenching apparatus, and quenching the metal pipes by cooling after heating by induction heating the metal pipes in the quenching apparatus.
Sensor comprising: - a casing delimiting an internal volume internal to the casing and having a passage extending between this internal volume and a first external zone external to the casing; - a moving part able to move inside the said internal volume of the casing; - detection means for detecting a movement of the said moving part with respect to the casing, these detection means comprising a detection portion extending in the passage, between the said first external zone external to the casing and the said internal volume internal to the casing, this detection portion also having a groove open to the outside of the detection portion for orienting the portion of the detection means relative to the casing, this groove extending between the said first external zone external to the casing and the said internal volume internal to the casing, characterized in that it comprises first sealing means positioned around the detection portion and placed inside the passage, these first sealing means being arranged in such a way as to prevent fluid from passing between the internal volume and the first external zone external to the casing via said groove. - a casing delimiting an internal volume internal to the casing and having a passage extending between this internal volume and a first external zone external to the casing; - a moving part able to move inside the said internal volume of the casing; - detection means for detecting a movement of the said moving part with respect to the casing, these detection means comprising a detection portion extending in the passage, between the said first external zone external to the casing and the said internal volume internal to the casing, this detection portion also having a groove open to the outside of the detection portion for orienting the portion of the detection means relative to the casing, this groove extending between the said first external zone external to the casing and the said internal volume internal to the casing, characterized in that it comprises first sealing means positioned around the detection portion and placed inside the passage, these first sealing means being arranged in such a way as to prevent fluid from passing between the internal volume and the first external zone external to the casing via said groove.
A method of fabricating a polycrystalline diamond material, comprising: placing a powder layer of nano-sized grain growth inhibitor particles next to a mixture of diamond particles, the mixture of diamond particles having an average particle size of 1 micron or less, the grain growth inhibitor being titanium containing particles selected from the group consisting of TiC, TiCxNy and TiN, and combinations thereof, placing a substrate next to the powder layer; the substrate comprising tungsten carbide and a catalyst metal, and sintering the mixture of diamond particles and the powder layer of grain growth inhibitor particles at high pressure and high temperature to create a polycrystalline structure of sintered diamond grains, wherein the grain growth inhibitor layer is bonded to the substrate and to the polycrystalline structure of diamond grains at opposite sides, and is 20 -100 microns in thickness, and wherein the grain growth inhibitor layer comprises a plurality of titanium-containing particles being less than 800 nanometers in size; the plurality of titanium-containing particles is interspersed with tungsten and catalyst metal, the grain growth inhibitor layer comprising 1 to 25 atomic per cent (%) tungsten, 20 to 70 atomic per cent (%) titanium (Ti), 2 to 35 atomic per cent (%) cobalt (Co), and the balance carbon and nitrogen, and wherein the sintered diamond grains have an average size of 1 micron or less. placing a powder layer of nano-sized grain growth inhibitor particles next to a mixture of diamond particles, the mixture of diamond particles having an average particle size of 1 micron or less, the grain growth inhibitor being titanium containing particles selected from the group consisting of TiC, TiCxNy and TiN, and combinations thereof, placing a substrate next to the powder layer; the substrate comprising tungsten carbide and a catalyst metal, and sintering the mixture of diamond particles and the powder layer of grain growth inhibitor particles at high pressure and high temperature to create a polycrystalline structure of sintered diamond grains, wherein the grain growth inhibitor layer is bonded to the substrate and to the polycrystalline structure of diamond grains at opposite sides, and is 20 -100 microns in thickness, and wherein the grain growth inhibitor layer comprises a plurality of titanium-containing particles being less than 800 nanometers in size; the plurality of titanium-containing particles is interspersed with tungsten and catalyst metal, the grain growth inhibitor layer comprising 1 to 25 atomic per cent (%) tungsten, 20 to 70 atomic per cent (%) titanium (Ti), 2 to 35 atomic per cent (%) cobalt (Co), and the balance carbon and nitrogen, and wherein the sintered diamond grains have an average size of 1 micron or less.
A booster assembly (30, 130), comprising: a non-metallic spool (31, 131) having a forward end and an aft end; a plurality of rows of holes (49, 140), said holes being arranged in one or more rows extending circumferentially about said spool; a plurality of radially removable non-metallic blades extending through said plurality of rows of holes (40, 140) from an internal side of said non-metallic spool (31, 131) to an external side; and, said plurality of radially removable non-metallic blades each having a retention feature retaining said non-metallic blades along an interior side of said spool, wherein the spool (31, 131) comprises axial zones (170, 172, 174) of varying composite material layer orientation, characterized in that said axial zones comprise a first zone in which the layers of composite material are provided in a multi-directional layup wherein the various layers of composite material are laid up in multiple orientations, a second zone providing composite material laid up predominantly circumferentially, and a third zone wherein the composite material is laid up in predominantly axially directed plies, wherein the holes (40, 140) are provided in the third zone, a second zone, which provides for increased thickness in the area defining the holes (40, 140), is provided adjacent each axial end of the third zone, and a first zone is provided adjacent each second zone, whereby a second zone is axially interposed between each third zone and a first zone. a non-metallic spool (31, 131) having a forward end and an aft end; a plurality of rows of holes (49, 140), said holes being arranged in one or more rows extending circumferentially about said spool; a plurality of radially removable non-metallic blades extending through said plurality of rows of holes (40, 140) from an internal side of said non-metallic spool (31, 131) to an external side; and, said plurality of radially removable non-metallic blades each having a retention feature retaining said non-metallic blades along an interior side of said spool, wherein the spool (31, 131) comprises axial zones (170, 172, 174) of varying composite material layer orientation, characterized in that said axial zones comprise a first zone in which the layers of composite material are provided in a multi-directional layup wherein the various layers of composite material are laid up in multiple orientations, a second zone providing composite material laid up predominantly circumferentially, and a third zone wherein the composite material is laid up in predominantly axially directed plies, wherein the holes (40, 140) are provided in the third zone, a second zone, which provides for increased thickness in the area defining the holes (40, 140), is provided adjacent each axial end of the third zone, and a first zone is provided adjacent each second zone, whereby a second zone is axially interposed between each third zone and a first zone.
Apparatus providing a predefined coloured graphic representation (1, 2) for detection by a detector, comprising: at least one light source (4, 5) emitting definable light colours, characterized in that the apparatus further comprises the predefined coloured graphic representation (1, 2) comprising a code, wherein the at least one light source (4, 5) is adapted to illuminate the predefined coloured graphic representation (1, 2), so that depending on the illuminating light colour the predefined coloured graphic representation (1, 2) or a part of the coloured graphic representation (1, 2) is visible by the detector with a predefinable intensity and/or colour, a control unit for defining and providing an illumination sequence comprising different light colours emitted by the at least one light source (4, 5) for providing a change of visibility of the graphic representation (1, 2) or of a part of the graphic representation (1, 2) by the detector, and evaluating means for verifying a relationship of the provided predefined graphic representation (1, 2) with corresponding data relating to the provided illumination sequence detected by the detector by comparing this detection result with an expected illumination result. at least one light source (4, 5) emitting definable light colours, characterized in that the apparatus further comprises the predefined coloured graphic representation (1, 2) comprising a code, wherein the at least one light source (4, 5) is adapted to illuminate the predefined coloured graphic representation (1, 2), so that depending on the illuminating light colour the predefined coloured graphic representation (1, 2) or a part of the coloured graphic representation (1, 2) is visible by the detector with a predefinable intensity and/or colour, a control unit for defining and providing an illumination sequence comprising different light colours emitted by the at least one light source (4, 5) for providing a change of visibility of the graphic representation (1, 2) or of a part of the graphic representation (1, 2) by the detector, and evaluating means for verifying a relationship of the provided predefined graphic representation (1, 2) with corresponding data relating to the provided illumination sequence detected by the detector by comparing this detection result with an expected illumination result.
Strapping head for strapping a package/pallet with a first strap and a second strap that wrap the package/pallet along two orthogonal planes; said strapping head comprising: - a platform suitable for supporting said package/pallet; said platform comprising an upper surface, wherein said package/pallet is disposed, and a lower surface directed in opposite direction with respect to said upper surface; said platform having a polygonal shape with two parallel sides (15a, 15b) and two converging sides (16a, 16) that define a point under which said straps (91, 92) are crossed; - tensioning means disposed under said platform; said tensioning means cooperating with the platform to block a first blocking portion (91c, 92c) of each strap (91, 92); characterized in that it comprises - guide means to guide said platform along a horizontal axis between an advanced position and a retracted position; - blocking means disposed under said platform in correspondence of said point of the platform, when said platform is in advanced position; said blocking means cooperating with the platform to block a second blocking portion (91e, 92e) of each strap (91, 92); - welding means disposed under said platform between said tensioning means and said blocking means; said welding means being configured in such a way to weld two welding portions (91c, 92c, 91d, 92d) of the same strap (91, 92); and - cutting means disposed between said blocking means and said tensioning means; said cutting means being suitable for cutting said strap. - a platform suitable for supporting said package/pallet; said platform comprising an upper surface, wherein said package/pallet is disposed, and a lower surface directed in opposite direction with respect to said upper surface; said platform having a polygonal shape with two parallel sides (15a, 15b) and two converging sides (16a, 16) that define a point under which said straps (91, 92) are crossed; - tensioning means disposed under said platform; said tensioning means cooperating with the platform to block a first blocking portion (91c, 92c) of each strap (91, 92); - guide means to guide said platform along a horizontal axis between an advanced position and a retracted position; - blocking means disposed under said platform in correspondence of said point of the platform, when said platform is in advanced position; said blocking means cooperating with the platform to block a second blocking portion (91e, 92e) of each strap (91, 92); - welding means disposed under said platform between said tensioning means and said blocking means; said welding means being configured in such a way to weld two welding portions (91c, 92c, 91d, 92d) of the same strap (91, 92); and - cutting means disposed between said blocking means and said tensioning means; said cutting means being suitable for cutting said strap.
Apparatus, comprising monitoring means adapted to monitor if an information about an emergency procedure is received, wherein the information comprises an internet protocol address from where at least one of a registration for the emergency procedure and an invitation to the emergency procedure is originated; characterized by: identifying means adapted to identify an identity of a user correlated to the internet protocol address; providing means adapted to provide the identity of the user in response to the information. monitoring means adapted to monitor if an information about an emergency procedure is received, wherein the information comprises an internet protocol address from where at least one of a registration for the emergency procedure and an invitation to the emergency procedure is originated; characterized by: identifying means adapted to identify an identity of a user correlated to the internet protocol address; providing means adapted to provide the identity of the user in response to the information. identifying means adapted to identify an identity of a user correlated to the internet protocol address; providing means adapted to provide the identity of the user in response to the information.
A disposable heart rate indicator (100, 200, 400, 600) for indicating a heart rate of an immobile person, comprising: a power source for generating power to the heart rate indicator (100, 200, 400, 600), at least two electrodes (104A, 104B) for detecting a person's heart beat, the electrodes (104A, 104B) being attachable to the person's skin for duration of use and forming a heart beat detection area; a processor (106, 606) and a light emitting diode, the processor (106, 606) being operatively coupled to the at least two electrodes (104A, 104B) and being configured to receive a signal on each heart beat detected by the electrodes (104A, 104B) and visually indicate a detected heart rate by means of optical light emitted by the light emitting diode by flashing the diode in accordance with the pace of the detected heart beats; and electrical wired conductor means coupled between the light emitting diode and the processor (106, 606), the conductor means being configured to extend from the heart beat detection area and the processor (106, 606) and fastening means for fastening the light emitting diode to the person. a power source for generating power to the heart rate indicator (100, 200, 400, 600), at least two electrodes (104A, 104B) for detecting a person's heart beat, the electrodes (104A, 104B) being attachable to the person's skin for duration of use and forming a heart beat detection area; a processor (106, 606) and a light emitting diode, the processor (106, 606) being operatively coupled to the at least two electrodes (104A, 104B) and being configured to receive a signal on each heart beat detected by the electrodes (104A, 104B) and visually indicate a detected heart rate by means of optical light emitted by the light emitting diode by flashing the diode in accordance with the pace of the detected heart beats; and electrical wired conductor means coupled between the light emitting diode and the processor (106, 606), the conductor means being configured to extend from the heart beat detection area and the processor (106, 606) and fastening means for fastening the light emitting diode to the person.
Mount for accessories of a weapon, wherein the weapon has at least one receiving rail or at least one depression resembling a receiving means, wherein a form-fitted connection between the receiving rail, or the at least one depression resembling a receiving means, and the mount can be created by a clamping lever incorporated in the mount with an integrated solid-body spring, wherein the mount is configured in such a manner that during clamping the clamping lever presses straight onto the receiving rail, or the at least one depression resembling a receiving means, or onto a sliding plate which is pressed by the clamping lever onto the receiving rail, or the at least one depression resembling a receiving means, wherein the clamping lever has a clamping lever head which has a groove realizing the solid-body spring.
Process for preparing a polymer based on N-vinyllactam monomer units, which comprises a step of controlled free-radical polymerization of a composition comprising: - monomers containing N-vinyllactam monomers, which are identical or different, and - a control agent for the free-radical polymerization, and - a free-radical polymerization initiator, which is a redox system comprising a reducing agent and an oxidizing agent, in which the difference between the standard redox potentials of the oxidizer and the reducer (E ox -E red) is at least 1 V, in which step is carried out in aqueous medium. - monomers containing N-vinyllactam monomers, which are identical or different, and - a control agent for the free-radical polymerization, and - a free-radical polymerization initiator, which is a redox system comprising a reducing agent and an oxidizing agent, in which the difference between the standard redox potentials of the oxidizer and the reducer (E ox -E red) is at least 1 V,
A gasket (112; 212; 312; 412) for an engine comprising a gasket opening (123; 223) and being structured with a control gap (120; 220; 320; 420) or being structured to form a control gap (120; 220; 320; 420) when in situ between a cylinder head (110; 310) and cylinder block (116; 316), said gasket opening (123; 223) being sized and arranged to provide a fluid pathway between a bore opening in a cylinder block (116; 316) and a bore opening in a cylinder head (110; 310) and said control gap (120; 220; 320; 420) being configured and arranged to selectively restrict that fluid pathway such that gas may freely pass through the opening (123; 223) in the gasket whereas coolant can only restrictively pass through the opening (123; 223) in the gasket, wherein: the control gap (120; 220; 320; 420) in the gasket opening (123; 223) comprises an upper wall (103; 203; 303), a lower wall (105; 205; 305; 405) and side walls (106; 206), the height of the control gap being defined by the distance between the upper wall (103; 203; 303) and the lower wall and wherein the height of the control gap is dimensioned such that the viscous drag of coolant passing between the upper and lower walls is significant enough to prevent or at least minimise the flow of coolant out of the gasket opening (123; 223) and into the opening in the cylinder head (110; 310).