A method for resolving apparent peaks in a sample chromatogram into one or more constituent peaks, comprising: (a) identifying, by a processor of a computing device, a plurality of well-defined peaks from among a set of peaks in a chromatogram, wherein each of the plurality of well-defined peaks is sufficiently separated from adjacent peaks among the set of peaks in the chromatogram and its height, spacing and area are identifiable, in accordance with predetermined criteria; (b) calculating, by the processor, an observed peak resolution value, as a function of peak position, of each of the plurality of well-defined peaks; (c) extrapolating, by the processor, the observed peak resolution values of the plurality of well-defined peaks in the chromatogram to obtain a predicted peak resolution value, as a function of peak position, of one or more apparent peaks in the chromatogram, wherein the extrapolating being based on one or more of the assumptions that peak resolution varies gradually, peak spacing gradually increases from the beginning to the middle of a chromatogram, peak spacing gradually decreases from the middle to the end of a chromatogram, and peak width gradually increases from the beginning to the end of a chromatogram., wherein the one or more apparent peaks comprise the peaks among the set of peaks in the chromatogram that do not satisfy the predetermined criteria of a well-defined peak, and wherein each of the one or more apparent peaks comprises one or more constituent peaks; (d) calculating, by the processor, an observed peak resolution value, as a function of peak position, of each of the one or more apparent peaks; (e) correlating, by the processor, for each of the one or more apparent peaks, an observed peak resolution value with a multiple of the predicted peak resolution value of the apparent peak at a corresponding peak position by calculating a ratio of the observed peak resolution value of the apparent peak, and the predicted peak resolution value of the apparent peak at the corresponding peak position; and (f) resolving, by the processor, the apparent peaks by correlating the ratio of each of the one or more apparent peaks with a number of constituent peaks in the respective apparent peak, each of the constituent peaks representing a single component of a mixture of components. (a) identifying, by a processor of a computing device, a plurality of well-defined peaks from among a set of peaks in a chromatogram, wherein each of the plurality of well-defined peaks is sufficiently separated from adjacent peaks among the set of peaks in the chromatogram and its height, spacing and area are identifiable, in accordance with predetermined criteria; (b) calculating, by the processor, an observed peak resolution value, as a function of peak position, of each of the plurality of well-defined peaks; (c) extrapolating, by the processor, the observed peak resolution values of the plurality of well-defined peaks in the chromatogram to obtain a predicted peak resolution value, as a function of peak position, of one or more apparent peaks in the chromatogram, wherein the extrapolating being based on one or more of the assumptions that peak resolution varies gradually, peak spacing gradually increases from the beginning to the middle of a chromatogram, peak spacing gradually decreases from the middle to the end of a chromatogram, and peak width gradually increases from the beginning to the end of a chromatogram., wherein the one or more apparent peaks comprise the peaks among the set of peaks in the chromatogram that do not satisfy the predetermined criteria of a well-defined peak, and wherein each of the one or more apparent peaks comprises one or more constituent peaks; wherein the extrapolating being based on one or more of the assumptions that peak resolution varies gradually, peak spacing gradually increases from the beginning to the middle of a chromatogram, peak spacing gradually decreases from the middle to the end of a chromatogram, and peak width gradually increases from the beginning to the end of a chromatogram., wherein the one or more apparent peaks comprise the peaks among the set of peaks in the chromatogram that do not satisfy the predetermined criteria of a well-defined peak, and wherein each of the one or more apparent peaks comprises one or more constituent peaks; (d) calculating, by the processor, an observed peak resolution value, as a function of peak position, of each of the one or more apparent peaks; (e) correlating, by the processor, for each of the one or more apparent peaks, an observed peak resolution value with a multiple of the predicted peak resolution value of the apparent peak at a corresponding peak position by calculating a ratio of the observed peak resolution value of the apparent peak, and the predicted peak resolution value of the apparent peak at the corresponding peak position; and (f) resolving, by the processor, the apparent peaks by correlating the ratio of each of the one or more apparent peaks with a number of constituent peaks in the respective apparent peak, each of the constituent peaks representing a single component of a mixture of components.