mhurhangee/ep-ind-claims huggingface dataset:
A machine tool, comprising a machine frame in which functional components are arranged generating heat during the operation, and which has cavity structures for forming a circulation circuit in which a coolant is circulated inside said machine frame, wherein said machine frame has first areas in which the heat-generating functional components are arranged, and second areas spaced apart from said first areas, such that a heat input in said second areas which is generated by said functional components, is smaller than that in said first areas, and said cavity structures have first portions arranged in said first areas and second portions arranged in said second areas, wherein said cavity structures located in said machine frame are dimensioned such that, when said coolant is circulated from said first portions to said second portions, heat input by said functional components is dissipated into said second areas so as to cause a temperature equalization between said first and second areas, wherein a pump for circulating said coolant is provided and said first portions and said second portions of said cavity structures form a closed circuit fully arranged within said machine frame such that temperature equalization takes place within said machine frame, characterized in that said cavity structures for forming the circulation circuit are formed at least in part of cavities of a rib structure of said machine frame, and wherein said cavity structures are connected with each other via through holes.
A method of raising fish in a recirculated aquaculture system abbreviated RAS, comprising a fish holding unit in fluid communication with a water supply, the fish holding unit containing a volume of water defining a water depth, the water in the fish holding unit having an osmotic concentration, a conductivity, an oxygen concentration, a CO 2 concentration, a N 2 concentration, a NH 4 + concentration, a temperature, and a pH, the recirculated aquaculture system further comprising a recirculation conduit, the method comprising the steps of: monitoring at least one parameter selected from the osmotic concentration, the conductivity, the oxygen concentration, the CO 2 concentration, the N 2 concentration, the NH 4 + concentration, the temperature and the pH of the water in the fish holding unit; providing a flow of non-recirculated water to the water supply and providing a difference in the at least one parameter of the non-recirculated water of: i) an osmotic concentration difference of at least 1 mOsm/kg; ii) a conductivity difference of at least 0.01 μS/cm; iii) an oxygen concentration difference of at least 0.05 mg/kg; iv) a CO 2 concentration difference of at least 0.05 mg/kg; v) a N 2 concentration difference of at least 0.05 mg/kg; vi) a NH 4 + concentration difference of at least 0.05 mg/kg; vii) a temperature difference of at least 0.1 °C; and viii) a pH difference of at least 0.1 compared to the at least one parameter of the water of the fish holding unit; providing feed pellets; and adding the feed pellets to the non-recirculated water and hydraulically transporting the feed pellets to the fish holding unit. monitoring at least one parameter selected from the osmotic concentration, the conductivity, the oxygen concentration, the CO 2 concentration, the N 2 concentration, the NH 4 + concentration, the temperature and the pH of the water in the fish holding unit; providing a flow of non-recirculated water to the water supply and providing a difference in the at least one parameter of the non-recirculated water of: i) an osmotic concentration difference of at least 1 mOsm/kg; ii) a conductivity difference of at least 0.01 μS/cm; iii) an oxygen concentration difference of at least 0.05 mg/kg; iv) a CO 2 concentration difference of at least 0.05 mg/kg; v) a N 2 concentration difference of at least 0.05 mg/kg; vi) a NH 4 + concentration difference of at least 0.05 mg/kg; vii) a temperature difference of at least 0.1 °C; and viii) a pH difference of at least 0.1 i) an osmotic concentration difference of at least 1 mOsm/kg; ii) a conductivity difference of at least 0.01 μS/cm; iii) an oxygen concentration difference of at least 0.05 mg/kg; iv) a CO 2 concentration difference of at least 0.05 mg/kg; v) a N 2 concentration difference of at least 0.05 mg/kg; vi) a NH 4 + concentration difference of at least 0.05 mg/kg; vii) a temperature difference of at least 0.1 °C; and viii) a pH difference of at least 0.1 compared to the at least one parameter of the water of the fish holding unit; providing feed pellets; and adding the feed pellets to the non-recirculated water and hydraulically transporting the feed pellets to the fish holding unit.
A magnetron sputtering apparatus comprising: a magnetic array arranged to create a magnetic field in the vicinity of a tubular target which target at least partially surrounds the magnetic array and acts as a cathode; an anode (2b,13); means adapted to enhance the magnetic field; the magnetic array comprising a mounting plate and one or more magnets mounted on said mounting plate, characterised in that the means are adapted to produce a relatively low impedance path for electrons flowing from the cathode to the anode; and the magnetic array is an asymmetric array arranged to create an asymmetric magnetic field, asymmetry in the magnetic field being achieved by any one or more of the group consisting of: the position of the magnets being located asymmetrically about an axis of the mounting plate; the magnets being of unequal sizes or strengths; the presence of ferromagnetic or non-ferromagnetic materials which break the symmetry of the interaction between two or more of the magnets; and the asymmetric shape of the mounting plate. a magnetic array arranged to create a magnetic field in the vicinity of a tubular target which target at least partially surrounds the magnetic array and acts as a cathode; an anode (2b,13); means adapted to enhance the magnetic field; the magnetic array comprising a mounting plate and one or more magnets mounted on said mounting plate, characterised in that the means are adapted to produce a relatively low impedance path for electrons flowing from the cathode to the anode; and the magnetic array is an asymmetric array arranged to create an asymmetric magnetic field, asymmetry in the magnetic field being achieved by any one or more of the group consisting of: the position of the magnets being located asymmetrically about an axis of the mounting plate; the magnets being of unequal sizes or strengths; the presence of ferromagnetic or non-ferromagnetic materials which break the symmetry of the interaction between two or more of the magnets; and the asymmetric shape of the mounting plate.
An ethylene separation process comprising: introducing a feed stream comprising ethylene and butene into a de-ethenizer; and separating the ethylene from the butene via fractional distillation within the de-ethenizer to form an overhead stream comprising separated ethylene and a bottoms stream comprising separated butene, wherein the de-ethenizer operates at a pressure of less than 2.41 MPaG (350 psig) and further comprising introducing fresh ethylene to the de-ethenizer as reflux supplement. introducing a feed stream comprising ethylene and butene into a de-ethenizer; and separating the ethylene from the butene via fractional distillation within the de-ethenizer to form an overhead stream comprising separated ethylene and a bottoms stream comprising separated butene, wherein the de-ethenizer operates at a pressure of less than 2.41 MPaG (350 psig) and further comprising introducing fresh ethylene to the de-ethenizer as reflux supplement.
An antibody-drug conjugate represented by Formula Ab-(L-D) p, Ab is an antibody; L is a peptidomimetic linker represented by the following formula -Str- -Sp- wherein Str is a stretcher unit covalently attached to Ab; Sp is a bond or spacer unit covalently attached to a drug moiety; PM is a non-peptide chemical moiety selected from the group consisting of: each R 1 is independently C 1 -C 10 alkyl, C 1 -C 10 alkenyl, (C 1 -C 10 alkyl)NHC NH 2 or (C 1 -C 10 alkyl)NHC NH 2; R 4 and R 5 are each independently C 1 -C 10 alkyl, C 1 -C 10 alkenyl, arylalkyl, heteroarylalkyl, (C 1 -C 10 alkyl)OCH 2 -, or R 4 and R 5 together may form a C 3 -C 7 cycloalkyl ring; p is an integer from 1 to 8; and D is a drug moiety. Ab is an antibody; L is a peptidomimetic linker represented by the following formula -Str- -Sp- Str is a stretcher unit covalently attached to Ab; Sp is a bond or spacer unit covalently attached to a drug moiety; PM is a non-peptide chemical moiety selected from the group consisting of: each R 1 is independently C 1 -C 10 alkyl, C 1 -C 10 alkenyl, (C 1 -C 10 alkyl)NHC NH 2 or (C 1 -C 10 alkyl)NHC NH 2; R 4 and R 5 are each independently C 1 -C 10 alkyl, C 1 -C 10 alkenyl, arylalkyl, heteroarylalkyl, (C 1 -C 10 alkyl)OCH 2 -, or R 4 and R 5 together may form a C 3 -C 7 cycloalkyl ring; p is an integer from 1 to 8; and D is a drug moiety.
Plunge cable saw having a sawing unit for extracting a massive workpiece, such as rocks or concrete foundations, suitable for extracting a block of stone from a mountain, wherein the sawing unit comprises a saw cable, in particular provided with diamond segments, as well as a guide device for the saw cable, wherein the guide device has at least two longitudinal arms, which are arranged at a distance from one another, are formed by telescopic arms and on which the saw cable is guided, wherein a distance of the two longitudinal arms relative to one another is variable, wherein the saw cable is drivable by a drive, wherein the longitudinal extension of the two longitudinal arms is variable, so that the spatial extension of the guide device is variable while the saw cable is driven, and wherein deflection pulleys, in which the saw cable is guided, are arranged on the telescopic arms, characterized in that the plunge cable saw has a cable accumulator having at least two deflection pulleys in which the saw cable is guided several times, and in that deflection pulleys of the guide device are formed by a milling head.
A method of identifying a patient at risk for suffering an adverse effect from administration of an opioid, wherein the adverse effect is respiratory depression comprising analysing a sample from the patient for the presence or absence of at least one polymorphism indicating that the patient has an elevated risk for suffering the adverse opioid-related effect, selected from: AA or AC genotype of fatty acid amide hydrolase (FAAH) rs2295632, or GG or GA genotype of adrenoceptor beta 2 (ADRB2) rs1042713.
A method of producing a capillary tube (1; 41) from glass, comprising a method step in which a tubular preform having an outer diameter D OD, an inner diameter D ID and a diameter ratio D rel - with D rel = D OD /D ID - is softened zonally in a heating zone heated to a drawing temperature T draw, and a capillary strand (1; 41) having an outer diameter d OD, an inner diameter d ID and a diameter ratio d rel - with d rel = d OD /d ID - is drawn off continuously from the softened region at a draw speed v draw, and the capillary tube (1; 41) is cut to length therefrom, characterized in that the capillary bore (2; 42) is subjected in the heating zone to a shrinkage process based on the action of drawing temperature T draw and surface tension in such a way that the diameter ratio d rel of the capillary strand (1; 41) is adjusted to a value greater than the diameter ratio D rel of the preform by at least a factor of 5, and wherein a multimode optical fiber preform or a single-mode optical fiber preform with a preform core surrounding an inner bore and a preform cladding covering the preform core is employed as the preform, and a capillary strand (1; 41) is drawn therefrom having a capillary core (3; 43) surrounding a capillary bore (2; 42) and a capillary cladding (4; 44) covering the capillary core (3; 43).
Accessory for steam cooking comprising a tray for recovering condensates intended to rest on a mixing bowl of a household appliance comprising means for heating the contents of the mixing bowl, with the tray comprising a cavity for recovering condensates and two gripping handles arranged symmetrically on either side of the cavity, with the cavity comprising a bottom comprising a chimney projection provided with a central orifice allowing for the passage of steam, said accessory also comprising at least one basket for cooking food which is positioned on said tray, characterised in that the chimney comprises, in the vicinity of the upper end thereof, an annular wall extending around the central orifice and transversally to the chimney, and in that the chimney comprises, opposite each gripping handle, a deflecting wall rising above the level of the annular wall.
A smart electronic personal identification document, comprising: an inner page, a smart identification module including a contactless chip module and an antenna, said smart identification module being operative to store and exchange personal identification information contactlessly with an external reader; characterized in that it further comprises an anti-skimming element disposed adjacent to said smart identification module, said anti-skimming element being configured for preventing unauthorized theft of said information, wherein said anti-skimming element includes a switching arrangement electrically connected to said smart identification module, said switching arrangement is configured for selectively enabling and disabling transmission of said information by said smart identification module, said switching arrangement includes a light sensor, disposed on the inner page of said smart electronic personal identification document, and said light sensor is configured such that, when said personal identification document is opened to said page, and said_light sensor is exposed to light above a threshold light level, said switching arrangement enables transmission of said information by said smart identification module. an inner page, a smart identification module including a contactless chip module and an antenna, said smart identification module being operative to store and exchange personal identification information contactlessly with an external reader; characterized in that it further comprises an anti-skimming element disposed adjacent to said smart identification module, said anti-skimming element being configured for preventing unauthorized theft of said information, wherein said anti-skimming element includes a switching arrangement electrically connected to said smart identification module, said switching arrangement is configured for selectively enabling and disabling transmission of said information by said smart identification module, said switching arrangement includes a light sensor, disposed on the inner page of said smart electronic personal identification document, and said light sensor is configured such that, when said personal identification document is opened to said page, and said_light sensor is exposed to light above a threshold light level, said switching arrangement enables transmission of said information by said smart identification module.
A method of producing a tumor necrosis factor receptor immunoglobulin fusion protein (TNFR-Ig) in a large-scale production cell culture comprising the steps of: providing a cell culture comprising; mammalian cells that contain a gene encoding a TNFR-Ig of interest, which gene is expressed under condition of cell culture; and a medium containing glutamine, having (i) a cumulative amino acid amount per unit volume greater than 70mM; (ii) a molar cumulative glutamine to cumulative asparagine ratio of less than 2; (iii) a molar cumulative glutamine to cumulative total amino acid ratio of less than 0.2; and (iv) a combined cumulative amount of glutamine and asparagine per unit volume of greater than 16 mM; maintaining said culture in an initial growth phase under a first set of culture conditions for a first period of time sufficient to allow said cells to reproduce to a viable cell density within a range of 20%-80% of the maximal possible viable cell density if said culture were maintained under the first set of culture conditions; changing at least one of the culture conditions, so that a second set of culture conditions is applied; maintaining said culture for a second period of time under the second set of conditions and for a second period of time so that the TNFR-Ig accumulates in the cell culture. providing a cell culture comprising; mammalian cells that contain a gene encoding a TNFR-Ig of interest, which gene is expressed under condition of cell culture; and a medium containing glutamine, having (i) a cumulative amino acid amount per unit volume greater than 70mM; (ii) a molar cumulative glutamine to cumulative asparagine ratio of less than 2; (iii) a molar cumulative glutamine to cumulative total amino acid ratio of less than 0.2; and (iv) a combined cumulative amount of glutamine and asparagine per unit volume of greater than 16 mM; mammalian cells that contain a gene encoding a TNFR-Ig of interest, which gene is expressed under condition of cell culture; and a medium containing glutamine, having (i) a cumulative amino acid amount per unit volume greater than 70mM; (ii) a molar cumulative glutamine to cumulative asparagine ratio of less than 2; (iii) a molar cumulative glutamine to cumulative total amino acid ratio of less than 0.2; and (iv) a combined cumulative amount of glutamine and asparagine per unit volume of greater than 16 mM; maintaining said culture in an initial growth phase under a first set of culture conditions for a first period of time sufficient to allow said cells to reproduce to a viable cell density within a range of 20%-80% of the maximal possible viable cell density if said culture were maintained under the first set of culture conditions; changing at least one of the culture conditions, so that a second set of culture conditions is applied; maintaining said culture for a second period of time under the second set of conditions and for a second period of time so that the TNFR-Ig accumulates in the cell culture.
A composition comprising surface functionalized biodegradable particles comprising encapsulated gliadin or one or more antigenic gliadin epitopes, wherein the particle has a negative zeta potential and wherein said particle is between 0.1 μm and 10 μm in diameter, wherein the particles have a zeta potential of -100 mV to -40 mV.
Method for composing a set of floor panels for flooring a room, based on a data set in accordance at least with the ground surface area of said room, wherein the method contains the step of establishing a laying plan suitable for said room, whereby the step of establishing a laying plan is carried out by means of a computer, wherein the computer proposes a laying plan on the basis of said data set, taking into account desired limitations, wherein said limitations are used to restrict a database of possible solutions; characterized in that said limitations include excluding that short edges of floor panels in adjacent rows are positioned closer than a minimum distance to be maintained; and/or excluding that a short edge of a floor panel is positioned closer than a minimum distance to be maintained from the start or the end of a row.
A container having a wall with a thickness defined by inner and outer surfaces (16, 18), said inner surface defining an internal cavity for receiving fluid, the container having an opening through which fluid can enter/exit the container, said opening being connected to a fluid conduit at least a length of which extends through the wall in between the inner and outer surfaces (16, 18) thereof to form an integral inertance tube, which fluid conduit exits through the inner surface to communicate with the internal cavity.
A method for producing a chemically modified collagen or gelatin, wherein collagen or gelatin is chemically modified in a reaction solution containing an organic fluorine compound, wherein the chemical modification is an introduction of a functional group into collagen or gelatin, and wherein a compound which is used for the chemical modification of collagen or gelatin is a compound having carbonate ester group, epoxide group, ester group, amide group, or dithiocarbamyl group.
A centrifugal compressor, comprising: an impeller provided in a main flow path and configured to pressurize a main flow of fluid; and a secondary flow path configured to provide a secondary flow by recirculating a portion of the main flow, wherein the secondary flow path is configured to receive and be formed by less than or equal to 15% of the main flow, wherein the secondary flow is introduced back into the main flow path by a plurality of injection nozzles, the injection nozzles each having a diameter within a range of 300 to 500 microns, and wherein the injection nozzles are circumferentially spaced-apart from one another by an arc length within a range of 8 to 25 of the diameters. an impeller provided in a main flow path and configured to pressurize a main flow of fluid; and a secondary flow path configured to provide a secondary flow by recirculating a portion of the main flow, wherein the secondary flow path is configured to receive and be formed by less than or equal to 15% of the main flow, wherein the secondary flow is introduced back into the main flow path by a plurality of injection nozzles, the injection nozzles each having a diameter within a range of 300 to 500 microns, and wherein the injection nozzles are circumferentially spaced-apart from one another by an arc length within a range of 8 to 25 of the diameters.
An evaporator for an absorption heat pump or a single coolant cooling process, the evaporator comprising a number of stacked plates (200; 400) provided with a pressed pattern to hold the plates on a distance from one another to form a heat exchanging strip (300; 500; 700; 2002), vapor leading spaces (295; 495; 2001) and outer walls (210; 410), the heat exchanging strip being designed such that flow channels are formed by internal surfaces of the strip, said flow channels connecting a heat carrier inlet and a heat carrier outlet, wherein a coolant forms a falling film on external surfaces of the heat carrier channels by being provided above the heat carrier channels by a coolant inlet (2110; 1310; 1210; 1110; 440; 240), wherein coolant being vaporized from the external surfaces by heat from a heat carrier flowing from the inlet to the outlet rapidly enters the vapor leading spaces (295; 495; 2001), and wherein the vapor leading spaces (295; 495; 2001) are provided between the heat exchanging strip (300; 500; 700; 2002) and the outer walls (210; 410), characterized by a gas outlet (280; 1320) situated above the coolant inlet (2110; 1310; 1210; 1110; 440; 240).