A method for forming an applicator, the method comprising steps of a. creating a digital geometric representation of a target structure, the target structure having a flatness ratio defined as the ratio of a projected area, projected from a top down normal to a horizontal supporting surface, to an actual printable surface area; b. forming the applicator using the digital geometric representation of the target structure, the applicator having a target structure contacting surface, comprising: creating a physical representation of at least a portion of the target structure according to the digital geometric representation; forming the applicator using the physical representation of the target structure, the applicator having a target structure contacting surface, wherein the created physical representation of the target structure has a flatness ratio which is higher than the flatness ratio of the target structure, or creating a physical representation of at least a portion of the negative of the target structure according to the digital geometric representation; the physical representation having a target structure contacting surface wherein the negative of the target structure has a flatness ratio which is higher than the flatness ratio of the target structure, and wherein the outer perimeter of the applicator is sized according to the size and shape of the target surface; and c. disposing an active agent upon the target structure contacting surface of the applicator. a. creating a digital geometric representation of a target structure, the target structure having a flatness ratio defined as the ratio of a projected area, projected from a top down normal to a horizontal supporting surface, to an actual printable surface area; b. forming the applicator using the digital geometric representation of the target structure, the applicator having a target structure contacting surface, comprising: creating a physical representation of at least a portion of the target structure according to the digital geometric representation; forming the applicator using the physical representation of the target structure, the applicator having a target structure contacting surface, wherein the created physical representation of the target structure has a flatness ratio which is higher than the flatness ratio of the target structure, or creating a physical representation of at least a portion of the negative of the target structure according to the digital geometric representation; the physical representation having a target structure contacting surface wherein the negative of the target structure has a flatness ratio which is higher than the flatness ratio of the target structure, and wherein the outer perimeter of the applicator is sized according to the size and shape of the target surface; and creating a physical representation of at least a portion of the target structure according to the digital geometric representation; forming the applicator using the physical representation of the target structure, the applicator having a target structure contacting surface, wherein the created physical representation of the target structure has a flatness ratio which is higher than the flatness ratio of the target structure, or creating a physical representation of at least a portion of the negative of the target structure according to the digital geometric representation; the physical representation having a target structure contacting surface wherein the negative of the target structure has a flatness ratio which is higher than the flatness ratio of the target structure, c. disposing an active agent upon the target structure contacting surface of the applicator.