mhurhangee/ep-ind-claims huggingface dataset:
An apparatus, comprising: a left-ventricular assist device comprising: an impeller configured to be placed inside a left ventricle of a subject and to pump blood from the left ventricle to an aorta of the subject, by rotating; a frame disposed around the impeller; and a pump-outlet tube configured to traverse an aortic valve of the subject, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the pump-outlet tube is disposed within the subject's left ventricle, characterised in that the distal portion of the pump-outlet tube extends to a distal end of the frame and defines more than 10 blood-inlet openings that are sized such as (a) to allow blood to flow from the subject's left ventricle into the tube and (b) to block structures from the subject's left ventricle from entering into the frame, wherein a porosity of the distal portion of the pump-outlet tube, which defines the blood-inlet openings, is lower within a proximal region of the distal portion of the pump-outlet tube than within a distal region of the distal portion of the pump-outlet tube that is distal to the proximal region. an impeller configured to be placed inside a left ventricle of a subject and to pump blood from the left ventricle to an aorta of the subject, by rotating; a frame disposed around the impeller; and a pump-outlet tube configured to traverse an aortic valve of the subject, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the pump-outlet tube is disposed within the subject's left ventricle, characterised in that the distal portion of the pump-outlet tube extends to a distal end of the frame and defines more than 10 blood-inlet openings that are sized such as (a) to allow blood to flow from the subject's left ventricle into the tube and (b) to block structures from the subject's left ventricle from entering into the frame, wherein a porosity of the distal portion of the pump-outlet tube, which defines the blood-inlet openings, is lower within a proximal region of the distal portion of the pump-outlet tube than within a distal region of the distal portion of the pump-outlet tube that is distal to the proximal region.
Parking assistance system, having an input device in order to accept data from a sensor system (112, 114), wherein the sensor system is designed to detect at least one parking-space-bounding object (302, 304) before parking; a computation device in order to take the detected at least one parking-space-bounding object (302, 304) as a basis for computing a parking path (306, 308, 310); a parking device for performing the parking along the computed parking path (306, 308, 310), and an output device for outputting distance details for detected objects to a man/machine interface (118, 120); and the parking device is designed not to brake, when parking, for a non-parking-space-bounding object detected during parking; characterized in that the output device is designed to output, during parking, distance details for the non-parking-space-bounding object to the man/machine interface, and the output device is designed to output the distance details for the non-parking-space-bounding object when a distance from the non-parking-space-bounding object is shorter than a path that needs to be covered during parking to a stopping or redirection point on the computed parking path (306, 308, 310).
A process for the preparation of a catalyst comprising an active phase comprising at least one metal from group VIII selected from cobalt, nickel, ruthenium and iron, alone or as a mixture, and an oxide support selected from alumina or silica-alumina, said process comprising at least the linked sequence of the following stages: - a stage for impregnation of said oxide support, said stage for impregnation being realised by at least one solution containing at least one precursor of said metal of group VIII selected from cobalt, nickel, ruthenium and iron, - a rapid drying stage in which said impregnated oxide support is entrained by means of a gas, said impregnated oxide support being subjected in said stage to a temperature rise ramp of between 250 and 600°C/min, the residence time of said impregnated oxide support in said drying stage being between 1 second and 1 minute, and - a stage for calcination of said impregnated and dried oxide support, said stage for calcination being realised at a temperature comprised between 320 and 460 °C, and for a period of between 15 minutes and 15 hours, in order to obtain a catalyst in oxide form in which the metal of group VIII is homogeneously distributed. - a stage for impregnation of said oxide support, said stage for impregnation being realised by at least one solution containing at least one precursor of said metal of group VIII selected from cobalt, nickel, ruthenium and iron, - a rapid drying stage in which said impregnated oxide support is entrained by means of a gas, said impregnated oxide support being subjected in said stage to a temperature rise ramp of between 250 and 600°C/min, the residence time of said impregnated oxide support in said drying stage being between 1 second and 1 minute, and - a stage for calcination of said impregnated and dried oxide support, said stage for calcination being realised at a temperature comprised between 320 and 460 °C, and for a period of between 15 minutes and 15 hours,
Medicament delivery device comprising a housing, which housing is arranged to accommodate a medicament container, the device further comprises a drive mechanism capable of, upon activation, expel a dose of medicament from said medicament container, the drive mechanism comprising a flat spiral spring having a predetermined number of turns wherein the outermost turn has an outer end connected to the housing and has an inner end drivably connected to a drive nut of said drive mechanism, at least a part of the outermost turn of said flat spiral spring being positioned on an outer surface of said housing characterized in that said outermost turn of said spring runs along the circumference of said housing and said housing is arranged with an opening, preferably a longitudinally extending opening, through which said flat spiral spring may run.
Use of a veterinary composition comprising cabergoline to be administered to a ruminant in a single treatment and/or in repeated treatments either at the time of the implementation of a shortened dry period of 4 weeks or at the time of the implementation of or during the shortened dry period of 4 weeks, for ensuring or maintaining milk-producing ability of the ruminant during the subsequent lactation.
An image forming apparatus comprising: an image forming portion for forming an image on a recording material using toner containing parting material; a heating rotatable member and a pressing rotatable member forming a nip portion for fixing the image formed on the recording material by said image forming portion; a duct for discharging the air taken in from neighbourhood of an entrance of the nip portion through an air inlet port, a filter provided in an air flow path of said duct to collect fine particles produced from the parting material, a fan for sucking air into said duct, characterized in that the image forming apparatus is configured such that a distance, which is the shortest distance between the center of the air inlet port and the surface of said heating rotatable member, is d in mm, an area of said filter is Fs in cm^2, and an air flow speed in the filter is Fv in cm/s satisfy the following: 1.25 × d − 8.67 × 1000 Fv × 60 ≤ Fs < 200 × 1000 Fv × 60 an image forming portion for forming an image on a recording material using toner containing parting material; a heating rotatable member and a pressing rotatable member forming a nip portion for fixing the image formed on the recording material by said image forming portion; a duct for discharging the air taken in from neighbourhood of an entrance of the nip portion through an air inlet port, a filter provided in an air flow path of said duct to collect fine particles produced from the parting material, a fan for sucking air into said duct, characterized in that the image forming apparatus is configured such that a distance, which is the shortest distance between the center of the air inlet port and the surface of said heating rotatable member, is d in mm, an area of said filter is Fs in cm^2, and an air flow speed in the filter is Fv in cm/s satisfy the following: 1.25 × d − 8.67 × 1000 Fv × 60 ≤ Fs < 200 × 1000 Fv × 60
A frequency measuring device, comprising: a buffer delay amount measuring circuit including a plurality of buffers for being inputted with clock signals, that are synchronized with a reference signal calculated by positioning calculation, at different timings shifted by a fixed delay time, respectively, and being inputted with a sampling reference signal of a lower frequency than the clock signals, and respectively generating state data according to levels of the clock signals at a transition timing of the sampling reference signal, wherein the buffer delay amount measuring circuit outputs delay measurement data (Ds) comprised of a group of the state data from the plurality of buffers; a frequency measuring circuit including a plurality of buffers for being inputted with measuring signals (SS) at different timings shifted by a fixed delay time, respectively, being inputted with a sampling reference signal of a lower frequency than the measuring signals, and respectively generating state data according to levels of the measuring signals at a transition timing of the sampling reference signal, wherein the frequency measuring circuit outputs frequency measurement data (Ds) comprised of a group of the state data from the plurality of buffers; and a frequency calculator arranged to calculate the delay amount (τ B) between the buffers based on the delay measurement data (Ds), and to calculate a frequency or a cycle of the measuring signals based on the frequency measurement data (Ds) and the delay amount (τ B). a buffer delay amount measuring circuit including a plurality of buffers for being inputted with clock signals, that are synchronized with a reference signal calculated by positioning calculation, at different timings shifted by a fixed delay time, respectively, and being inputted with a sampling reference signal of a lower frequency than the clock signals, and respectively generating state data according to levels of the clock signals at a transition timing of the sampling reference signal, wherein the buffer delay amount measuring circuit outputs delay measurement data (Ds) comprised of a group of the state data from the plurality of buffers; a frequency measuring circuit including a plurality of buffers for being inputted with measuring signals (SS) at different timings shifted by a fixed delay time, respectively, being inputted with a sampling reference signal of a lower frequency than the measuring signals, and respectively generating state data according to levels of the measuring signals at a transition timing of the sampling reference signal, wherein the frequency measuring circuit outputs frequency measurement data (Ds) comprised of a group of the state data from the plurality of buffers; and a frequency calculator arranged to calculate the delay amount (τ B) between the buffers based on the delay measurement data (Ds), and to calculate a frequency or a cycle of the measuring signals based on the frequency measurement data (Ds) and the delay amount (τ B).
Method for operating a data storage system comprising a plurality of data storage units, wherein in the context of the method, IoT data which arises at one data point respectively is stored in at least one data storage unit, characterised in that an automatic selection of at least one data storage unit for storage of the IoT data takes place on the basis of metadata and the metadata is assigned to a data point, the metadata comprises at least one metadatum for specification of a latency of the IoT data arising at the respective data point, the selection of at least one data storage unit takes place on the basis of the at least one metadatum and a configuration of the data storage system, the configuration comprises a definition of an assignment of a latency or a latency region to respectively at least one data storage unit, wherein an adaptable latency value is initialised with a latency defined in the metadata, wherein on accessing the IoT data of a data point, in the context of a data activity recognition, the exceeding of a configurable activity threshold is monitored and wherein on exceeding the activity threshold, the adaptable latency value is reduced by a configurable amount. wherein in the context of the method, IoT data which arises at one data point respectively is stored in at least one data storage unit, characterised in that an automatic selection of at least one data storage unit for storage of the IoT data takes place on the basis of metadata and the metadata is assigned to a data point, the metadata comprises at least one metadatum for specification of a latency of the IoT data arising at the respective data point, the selection of at least one data storage unit takes place on the basis of the at least one metadatum and a configuration of the data storage system, the configuration comprises a definition of an assignment of a latency or a latency region to respectively at least one data storage unit, wherein an adaptable latency value is initialised with a latency defined in the metadata, wherein on accessing the IoT data of a data point, in the context of a data activity recognition, the exceeding of a configurable activity threshold is monitored and wherein on exceeding the activity threshold, the adaptable latency value is reduced by a configurable amount.
A dipterous insect attracting device, comprising: a container provided with a lower opening arranged in a base of said container, said container being configured to contain an attractant composition, with the container being impermeable to the attractant; a wick coupleable to the base in fluid communication with the lower opening, configured to diffuse said attractant composition by capillarity; a cover coupleable to the base, said cover being configured to secure the wick in the base, such that the attractant composition can only be diffused through said wick, with the cover being impermeable to the attractant composition; characterised in that the container further comprises an upper opening and in that the device further comprises a cap coupled in a leak-tight manner to the upper opening of the container closing same, with the cap being impermeable to the attractant composition, the cap being configured to collapse or swell; wherein the attracting device is configured, for when the container contains said attractant composition, to be arranged in an activated position suitable for diffusing the attractant composition through the wick, and to be arranged in a deactivated position in which the attractant composition is not diffused through the wick, wherein said cap is configured to collapse or swell as the attractant composition is diffused through the wick. a container provided with a lower opening arranged in a base of said container, said container being configured to contain an attractant composition, with the container being impermeable to the attractant; a wick coupleable to the base in fluid communication with the lower opening, configured to diffuse said attractant composition by capillarity; a cover coupleable to the base, said cover being configured to secure the wick in the base, such that the attractant composition can only be diffused through said wick, with the cover being impermeable to the attractant composition; characterised in that the container further comprises an upper opening and in that the device further comprises a cap coupled in a leak-tight manner to the upper opening of the container closing same, with the cap being impermeable to the attractant composition, the cap being configured to collapse or swell; wherein the attracting device is configured, for when the container contains said attractant composition, to be arranged in an activated position suitable for diffusing the attractant composition through the wick, and to be arranged in a deactivated position in which the attractant composition is not diffused through the wick, wherein said cap is configured to collapse or swell as the attractant composition is diffused through the wick.
A method in a Vector Control Entity associated with a plurality of digital subscriber lines forming a vectoring group comprising a group A of lines having the same priority, the method comprising: when partial-vectoring resources are to be allocated among the lines within the vectoring group: - calculating a rate balancing metric, RBM, for each line i within the group A, indicative of the ratio between the bit rate of line i with a current vectoring resource allocation, and the estimated bit rate of line i assuming approximately no crosstalk within the vectoring group, - calculating an updated RBM for any line within the group A subjected to changes in vectoring resource allocation, and - allocating partial-vectoring resources to the line/s within the group A, based on the calculated RBMs, such as to reduce the difference in RBM between the lines. when partial-vectoring resources are to be allocated among the lines within the vectoring group: - calculating a rate balancing metric, RBM, for each line i within the group A, indicative of the ratio between the bit rate of line i with a current vectoring resource allocation, and the estimated bit rate of line i assuming approximately no crosstalk within the vectoring group, - calculating an updated RBM for any line within the group A subjected to changes in vectoring resource allocation, and - allocating partial-vectoring resources to the line/s within the group A, based on the calculated RBMs, such as to reduce the difference in RBM between the lines. - calculating a rate balancing metric, RBM, for each line i within the group A, indicative of the ratio between the bit rate of line i with a current vectoring resource allocation, and the estimated bit rate of line i assuming approximately no crosstalk within the vectoring group, - calculating an updated RBM for any line within the group A subjected to changes in vectoring resource allocation, and - allocating partial-vectoring resources to the line/s within the group A, based on the calculated RBMs, such as to reduce the difference in RBM between the lines.
A printing system comprising: a print controller configured to receive a sheet image as input, the print controller comprising a color management unit; a printer configured to output the sheet image processed by the color management unit; and a graphical user interface configured to receive, from a user, a pre-defined color parameter X for mapping the input color into the output color from a plurality of color parameters, the color management unit including: a color cache configured to store input colors and corresponding output colors; and a color engine configured to receive the input colors and perform Force-X transformations to map an input color into an output color based on the pre-defined color parameter, wherein the Force-X transformation verifies whether an input color from the pixels of an image to be printed by the printer is contained in the colors stored in cache, uses said corresponding output color if the verification is successful, or conversely uses look-up tables for generating the output color if the verification fails and stores in cache for later use the input color and the output color obtained from a look-up table contained in the color cache. a print controller configured to receive a sheet image as input, the print controller comprising a color management unit; a printer configured to output the sheet image processed by the color management unit; and a graphical user interface configured to receive, from a user, a pre-defined color parameter X for mapping the input color into the output color from a plurality of color parameters, the color management unit including: a color cache configured to store input colors and corresponding output colors; and a color engine configured to receive the input colors and perform Force-X transformations to map an input color into an output color based on the pre-defined color parameter, wherein the Force-X transformation verifies whether an input color from the pixels of an image to be printed by the printer is contained in the colors stored in cache, uses said corresponding output color if the verification is successful, or conversely uses look-up tables for generating the output color if the verification fails and stores in cache for later use the input color and the output color obtained from a look-up table contained in the color cache. a color cache configured to store input colors and corresponding output colors; and a color engine configured to receive the input colors and perform Force-X transformations to map an input color into an output color based on the pre-defined color parameter, wherein the Force-X transformation verifies whether an input color from the pixels of an image to be printed by the printer is contained in the colors stored in cache, uses said corresponding output color if the verification is successful, or conversely uses look-up tables for generating the output color if the verification fails and stores in cache for later use the input color and the output color obtained from a look-up table contained in the color cache.
An inhibitor of a BET protein for use in treating a proliferative disease, wherein the inhibitor of a BET protein is administered in combination with a Janus kinase inhibitor, wherein the Janus kinase inhibitor is tofacitinib, baricitinib, CYT387, lestaurtinib, pacritinib, TG101348, or a JAK1 selective inhibitor, and wherein said inhibitor of a BET protein is selected from: 7-(3,5-dimethylisoxazol-4-yl)-4-pyridin-2-yl-4,5-dihydroimidazo[1,5,4-de] [1,4]benzoxazin-2 -one; -7-(3,5-dimethylisoxazol-4-yl)-4-pyridin-2-y1-4,5-dihydroimidazo[1,5,4- de][1,4]benzoxazin-2 -one; and -2-(4-acetylpiperazin-1-yl)-7-(3,5-dimethylisoxazol-4-yl)-4-pyridin-2-yl-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine; and pharmaceutically acceptable salts of any of the aforementioned. 7-(3,5-dimethylisoxazol-4-yl)-4-pyridin-2-yl-4,5-dihydroimidazo[1,5,4-de] [1,4]benzoxazin-2 -one; -7-(3,5-dimethylisoxazol-4-yl)-4-pyridin-2-y1-4,5-dihydroimidazo[1,5,4- de][1,4]benzoxazin-2 -one; and -2-(4-acetylpiperazin-1-yl)-7-(3,5-dimethylisoxazol-4-yl)-4-pyridin-2-yl-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine; and pharmaceutically acceptable salts of any of the aforementioned.
An isolated human monoclonal anti-tau antibody, or a tau-binding fragment thereof which specifically binds a tau epitope which comprises the amino acid sequence of SEQ ID NO: 7 and (i) is capable of binding pathologically modified tau; (ii) binds to pathologically aggregated tau at the pre-tangle stage, in neurofibrillary tangles, neuropil threads and/or dystrophic neurites in the brain; and (iii) does not substantially bind to physiological forms of tau in the brain of a healthy donor when assessed by immunohistochemical staining. (i) is capable of binding pathologically modified tau; (ii) binds to pathologically aggregated tau at the pre-tangle stage, in neurofibrillary tangles, neuropil threads and/or dystrophic neurites in the brain; and (iii) does not substantially bind to physiological forms of tau in the brain of a healthy donor when assessed by immunohistochemical staining.