A manifold system adapted for use in a sample testing instrument, the manifold system comprising: (a) a manifold comprising: (i) a bottle receiver adapted to couple a bottle of reagent with an air intake channel and a reagent outlet channel when the bottle is placed in the bottle receiver, (ii) the air intake channel defined by the manifold and comprising an air channel bore, the air intake channel adapted to allow the flow of air from a connected air source to the bottle, and (iii) the reagent outlet channel defined by the manifold and comprising a reagent channel bore, the reagent outlet channel adapted to allow the flow of reagent from the bottle to a reagent distributor assembly of the sample testing instrument, (b) an air gasket (300, 301b) removably disposed within the air channel bore, wherein the air gasket (300, 301b) is adapted to seal and control the flow of air to the bottle; (c) a reagent gasket (300, 301a) removably disposed within the reagent channel bore, wherein the reagent gasket (300, 301a) is adapted to seal and control the flow of reagent from the bottle; and (d) a filter removably disposed within the reagent channel bore between the reagent gasket and the reagent distributor assembly and adapted to prevent particulate from passing through the reagent outlet channel towards the reagent distributor assembly. (a) a manifold comprising: (i) a bottle receiver adapted to couple a bottle of reagent with an air intake channel and a reagent outlet channel when the bottle is placed in the bottle receiver, (ii) the air intake channel defined by the manifold and comprising an air channel bore, the air intake channel adapted to allow the flow of air from a connected air source to the bottle, and (iii) the reagent outlet channel defined by the manifold and comprising a reagent channel bore, the reagent outlet channel adapted to allow the flow of reagent from the bottle to a reagent distributor assembly of the sample testing instrument, (i) a bottle receiver adapted to couple a bottle of reagent with an air intake channel and a reagent outlet channel when the bottle is placed in the bottle receiver, (ii) the air intake channel defined by the manifold and comprising an air channel bore, the air intake channel adapted to allow the flow of air from a connected air source to the bottle, and (iii) the reagent outlet channel defined by the manifold and comprising a reagent channel bore, the reagent outlet channel adapted to allow the flow of reagent from the bottle to a reagent distributor assembly of the sample testing instrument, (b) an air gasket (300, 301b) removably disposed within the air channel bore, wherein the air gasket (300, 301b) is adapted to seal and control the flow of air to the bottle; (c) a reagent gasket (300, 301a) removably disposed within the reagent channel bore, wherein the reagent gasket (300, 301a) is adapted to seal and control the flow of reagent from the bottle; and (d) a filter removably disposed within the reagent channel bore between the reagent gasket and the reagent distributor assembly and adapted to prevent particulate from passing through the reagent outlet channel towards the reagent distributor assembly.