A medical device for treating diseased tissue, the device comprising: a probe assembly comprising: a nonconductive handle including a first fluid line for receiving at least one of a first fluid and/or a therapeutic and a second fluid line for receiving a second fluid; a nonconductive distal portion extending from the handle, the distal portion comprising a rigid spherical body of a fixed diameter defining an interior chamber in fluid communication with the first fluid line and configured to receive at least one of the first fluid and therapeutic therefrom, the rigid spherical body also defining a plurality of ports (118, 119, 120) configured to allow passage of at least one of the first fluid and therapeutic from the interior chamber to an exterior surface of the rigid spherical body; an expandable inner balloon member disposed within the interior chamber and in fluid communication with the second fluid line and configured to transition from a collapsed configuration to an expanded configuration in response to delivery of a second fluid from the second fluid line; and a hydrophilic insert disposed within the interior chamber, the hydrophilic insert retained in place within the interior chamber between at least a portion of an exterior surface of the inner balloon member and an interior surface of the rigid spherical body, the hydrophilic insert configured to receive and evenly distribute at least one of the first fluid and the therapeutic to the plurality of ports (118, 119, 120); an electrode array comprising a plurality of independent conductive wires, each including a length positioned along the exterior surface of the rigid spherical body; and an active means for controlling transitioning of the inner balloon member between the collapsed configuration and expanded configuration and a plurality of configurations there between, wherein the active means is operable to inflate the inner balloon member to a first diameter during an ablation procedure to target tissue and to a second, larger diameter for delivery of the therapeutic to the target tissue. a probe assembly comprising: a nonconductive handle including a first fluid line for receiving at least one of a first fluid and/or a therapeutic and a second fluid line for receiving a second fluid; a nonconductive distal portion extending from the handle, the distal portion comprising a rigid spherical body of a fixed diameter defining an interior chamber in fluid communication with the first fluid line and configured to receive at least one of the first fluid and therapeutic therefrom, the rigid spherical body also defining a plurality of ports (118, 119, 120) configured to allow passage of at least one of the first fluid and therapeutic from the interior chamber to an exterior surface of the rigid spherical body; an expandable inner balloon member disposed within the interior chamber and in fluid communication with the second fluid line and configured to transition from a collapsed configuration to an expanded configuration in response to delivery of a second fluid from the second fluid line; and a hydrophilic insert disposed within the interior chamber, the hydrophilic insert retained in place within the interior chamber between at least a portion of an exterior surface of the inner balloon member and an interior surface of the rigid spherical body, the hydrophilic insert configured to receive and evenly distribute at least one of the first fluid and the therapeutic to the plurality of ports (118, 119, 120); a nonconductive handle including a first fluid line for receiving at least one of a first fluid and/or a therapeutic and a second fluid line for receiving a second fluid; a nonconductive distal portion extending from the handle, the distal portion comprising a rigid spherical body of a fixed diameter defining an interior chamber in fluid communication with the first fluid line and configured to receive at least one of the first fluid and therapeutic therefrom, the rigid spherical body also defining a plurality of ports (118, 119, 120) configured to allow passage of at least one of the first fluid and therapeutic from the interior chamber to an exterior surface of the rigid spherical body; an expandable inner balloon member disposed within the interior chamber and in fluid communication with the second fluid line and configured to transition from a collapsed configuration to an expanded configuration in response to delivery of a second fluid from the second fluid line; and a hydrophilic insert disposed within the interior chamber, the hydrophilic insert retained in place within the interior chamber between at least a portion of an exterior surface of the inner balloon member and an interior surface of the rigid spherical body, the hydrophilic insert configured to receive and evenly distribute at least one of the first fluid and the therapeutic to the plurality of ports (118, 119, 120); an electrode array comprising a plurality of independent conductive wires, each including a length positioned along the exterior surface of the rigid spherical body; and an active means for controlling transitioning of the inner balloon member between the collapsed configuration and expanded configuration and a plurality of configurations there between, wherein the active means is operable to inflate the inner balloon member to a first diameter during an ablation procedure to target tissue and to a second, larger diameter for delivery of the therapeutic to the target tissue.