A biomedical device for the therapeutic treatment of ulcers or lesions, particularly diabetic ulcers, said device consisting of a kit comprising in combination an electro-stimulator device and a dressing comprising a pharmaceutical composition and wherein the electro-stimulating device and the said dressing are applied simultaneously for treating an ulcer and which device comprises: - at least an electrical pulses generator, said electrical pulses being organized in sequences of electrical pulses having prefixed values of typical parameters, said typical parameters comprising one or more of the following parameters: amplitude, duration, frequency and/or waveform of said pulses and said parameters being configured according to the technology called FREMS acronym for Frequency Rhythmic Electric Modulation; - said generator comprising at least two separate stimulation channels, through which said sequences are delivered to body areas of an organism independently for each channel; - at least two stimulation electrodes (1, 2, 102, 105), each of which is connected or connectable to a respective stimulation channel and each of which is intended to be removably applied to one of two different prefixed body zones of an organism; - each electrode (1, 2, 102, 105) being applied externally to the patient's skin in correspondence with said prefixed area and with a prefixed position relationship with respect to the position of the remaining electrode or electrodes; - a control unit (14; 130) of said at least one electric pulse generator communicating with said electric pulse generator; - a command and/or data entry interface for setting and/or displaying setting data and/or setting settings of said one or more generator; - said dressing consisting of a film comprising a solution of povidone iodine (PVP-I) and sodium alginate (NaAlq) and intended to be applied while treating the ulcer; and wherein - the at least two electrodes (1, 2, 102, 105) are intended to be arranged on diametrically opposite sides of the lesion at a prefixed distance therefrom. - at least an electrical pulses generator, said electrical pulses being organized in sequences of electrical pulses having prefixed values of typical parameters, said typical parameters comprising one or more of the following parameters: amplitude, duration, frequency and/or waveform of said pulses and said parameters being configured according to the technology called FREMS acronym for Frequency Rhythmic Electric Modulation; - said generator comprising at least two separate stimulation channels, through which said sequences are delivered to body areas of an organism independently for each channel; - at least two stimulation electrodes (1, 2, 102, 105), each of which is connected or connectable to a respective stimulation channel and each of which is intended to be removably applied to one of two different prefixed body zones of an organism; - each electrode (1, 2, 102, 105) being applied externally to the patient's skin in correspondence with said prefixed area and with a prefixed position relationship with respect to the position of the remaining electrode or electrodes; - a control unit (14; 130) of said at least one electric pulse generator communicating with said electric pulse generator; - a command and/or data entry interface for setting and/or displaying setting data and/or setting settings of said one or more generator; - said dressing consisting of a film comprising a solution of povidone iodine (PVP-I) and sodium alginate (NaAlq) and intended to be applied while treating the ulcer; - the at least two electrodes (1, 2, 102, 105) are intended to be arranged on diametrically opposite sides of the lesion at a prefixed distance therefrom.