An arrangement for the individualized in-vitro patient blood analysis comprising a holography module, a Raman spectroscopy module, a biomarker module and an integrated flow controller which are connected in a data and information transmitting manner to a central control and computer unit which has an information transmitting connection to a database, wherein • the holography module consists of a holography sample preparation cartridge and a holography sample measurement unit which are microfluidically connected to each other, • the Raman spectroscopy module consists of a Raman spectroscopy sample preparation cartridge and a Raman spectroscopy sample measurement unit which are microfluidically connected to each other, • the biomarker module consists of a biomarker sample preparation cartridge and biomarker sample measurement unit which are microfluidically connected to each other, and the modules (1,2 and 3) are fluidically connected to a common blood sample supply and further fluid material supplies via the flow controller, wherein • the holography sample preparation cartridge consists of microstructured microfluidic lysis channels or dielectrophoresis channels with microelectrodes which are microfluidically connected to the flow controller, and the holography sample measurement unit is an arrangement for a lensless inline reflected-light microscope with a coherent illumination source and a detector array, • the Raman spectroscopy sample preparation cartridge consists of microstructured microfluidic lysis channels or dielectrophoresis channels with microelectrodes which are microfluidically connected to the flow controller, and the Raman spectroscopy sample measurement unit is a portable Raman spectroscopy system for mobile use, and • the biomarker sample preparation cartridge consists of microstructured microfluidic dielectrophoresis channels with microelectrodes or of microchannels which are provided with mechanical filters or cross-section changes and microfluidically connected to the flow controller, and the biomarker sample measurement unit is a photo sensor detector array arrangement with a coherent illumination source, wherein • the modules (1, 2 and 3), the blood sample supply and the fluid material supplies are combined in a fluidically integrated manner via the flow controller so that data flows (81, 82 and 83) for controlling the valves, for transferring the measured values from the modules (1, 2 and 3) to the central control and computer unit and for controlling the measurement processes in the modules (1, 2 and 3) may be effected by the central control and computer unit via the flow controller. • the holography module consists of a holography sample preparation cartridge and a holography sample measurement unit which are microfluidically connected to each other, • the Raman spectroscopy module consists of a Raman spectroscopy sample preparation cartridge and a Raman spectroscopy sample measurement unit which are microfluidically connected to each other, • the biomarker module consists of a biomarker sample preparation cartridge and biomarker sample measurement unit which are microfluidically connected to each other, and the modules (1,2 and 3) are fluidically connected to a common blood sample supply and further fluid material supplies via the flow controller, wherein • the holography sample preparation cartridge consists of microstructured microfluidic lysis channels or dielectrophoresis channels with microelectrodes which are microfluidically connected to the flow controller, and the holography sample measurement unit is an arrangement for a lensless inline reflected-light microscope with a coherent illumination source and a detector array, • the Raman spectroscopy sample preparation cartridge consists of microstructured microfluidic lysis channels or dielectrophoresis channels with microelectrodes which are microfluidically connected to the flow controller, and the Raman spectroscopy sample measurement unit is a portable Raman spectroscopy system for mobile use, and • the biomarker sample preparation cartridge consists of microstructured microfluidic dielectrophoresis channels with microelectrodes or of microchannels which are provided with mechanical filters or cross-section changes and microfluidically connected to the flow controller, and the biomarker sample measurement unit is a photo sensor detector array arrangement with a coherent illumination source, wherein • the modules (1, 2 and 3), the blood sample supply and the fluid material supplies are combined in a fluidically integrated manner via the flow controller so that data flows (81, 82 and 83) for controlling the valves, for transferring the measured values from the modules (1, 2 and 3) to the central control and computer unit and for controlling the measurement processes in the modules (1, 2 and 3) may be effected by the central control and computer unit via the flow controller.