mhurhangee/ep-ind-claims huggingface dataset:
A pharmaceutical composition, comprising a pharmaceutically acceptable carrier and a compound of formula or a salt thereof: wherein X is N or CH; each of R 1, R 2, R 3, R 4, and R 5, independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, heteroaryl, halo, OR a, SR a, COOR a, OC R a, C R a, C NR a R b, S 2 NR a R b, or NR a R b; each of R 6, R 7, R 8, and R 9, independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, heteroaryl, halo, OR a, SR a, COOR a, OC R a, C R a, C NR a R b, S 2 NR a R b, or NR a Rb; or R 6 and R 7, R 7 and R 8, or R 8 and R 9, together with the carbon atoms to which they are attached, are aryl, heteroaryl, C 3 -C 20 cycloalkyl, or C 1 -C 20 heterocycloalkyl; R 10 is C 1 -C 10 alkyl; each R a, independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, or heteroaryl; and each R b, independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, or heteroaryl. X is N or CH; each of R 1, R 2, R 3, R 4, and R 5, independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, heteroaryl, halo, OR a, SR a, COOR a, OC R a, C R a, C NR a R b, S 2 NR a R b, or NR a R b; each of R 6, R 7, R 8, and R 9, independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, heteroaryl, halo, OR a, SR a, COOR a, OC R a, C R a, C NR a R b, S 2 NR a R b, or NR a Rb; or R 6 and R 7, R 7 and R 8, or R 8 and R 9, together with the carbon atoms to which they are attached, are aryl, heteroaryl, C 3 -C 20 cycloalkyl, or C 1 -C 20 heterocycloalkyl; R 10 is C 1 -C 10 alkyl; each R a, independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, or heteroaryl; and each R b, independently, is H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, C 3 -C 20 cycloalkyl, C 3 -C 20 cycloalkenyl, C 1 -C 20 heterocycloalkyl, C 1 -C 20 heterocycloalkenyl, aryl, or heteroaryl.
A method comprising: obtaining an infrared spectrum of a blood plasma sample by analyzing the blood plasma sample by infrared spectroscopy; and based on the infrared spectrum, generating an output indicative of the presence of a malignant solid tumor or a pre-malignant condition, characterized in that the blood plasma sample includes a dried blood plasma sample and analyzing the blood plasma sample comprises analyzing the dried blood plasma sample. obtaining an infrared spectrum of a blood plasma sample by analyzing the blood plasma sample by infrared spectroscopy; and based on the infrared spectrum, generating an output indicative of the presence of a malignant solid tumor or a pre-malignant condition, characterized in that the blood plasma sample includes a dried blood plasma sample and analyzing the blood plasma sample comprises analyzing the dried blood plasma sample.
A compound having a structure represented by the following general formula or an edible salt thereof: wherein R1 and R2 each independently represent a hydrogen atom or a lower alkyl group having 1 to 3 carbon atoms; A represents a methylene group; and X represents a trimethylene group, a trimethylene group in which one of the methylene groups included therein is substituted with a thio group, a tetramethylene group in which one of the methylene groups thereof is replaced with a thio group, or a trimethylene group which is substituted with an alkyl group having 1 to 3 carbon atoms and one of the methylene groups of which is replaced with a thio group. wherein R1 and R2 each independently represent a hydrogen atom or a lower alkyl group having 1 to 3 carbon atoms; A represents a methylene group; and X represents a trimethylene group, a trimethylene group in which one of the methylene groups included therein is substituted with a thio group, a tetramethylene group in which one of the methylene groups thereof is replaced with a thio group, or a trimethylene group which is substituted with an alkyl group having 1 to 3 carbon atoms and one of the methylene groups of which is replaced with a thio group.
A method of determining whether a photocatalytic coating is present on the surface of a glass substrate, the method comprising: providing a source (110, 210, 310) of light energy, at least a portion of the light energy having a wavelength below about 350 nanometers (nm); directing light energy (112, 212, 312) from the source toward the surface of the substrate; detecting light energy reflected from the surface of the substrate; measuring an intensity level of the reflected light energy at wavelengths below about 350 nm; and determining whether a photocatalytic coating is present on the surface of the glass substrate based on the measured intensity level of reflected light energy at wavelengths below about 350 nm. providing a source (110, 210, 310) of light energy, at least a portion of the light energy having a wavelength below about 350 nanometers (nm); directing light energy (112, 212, 312) from the source toward the surface of the substrate; detecting light energy reflected from the surface of the substrate; measuring an intensity level of the reflected light energy at wavelengths below about 350 nm; and determining whether a photocatalytic coating is present on the surface of the glass substrate based on the measured intensity level of reflected light energy at wavelengths below about 350 nm.
Osseous anchor for anchoring an intervertebral implant in osseous tissue of a vertebra, wherein the anchor includes a plate having a far end bearing a part curved to fold over itself which is able to be interlocked onto means for clasping the osseous anchor on said implant, so as to retain said implant against said osseous tissue, while allowing removal of the osseous anchor from the implant, characterised in that the plate has an overall elongated rectangular shape of substantially constant breadth and thickness.
An orthopedic surgical device for use in operating on a target bone, comprising: a cut guide configured to be adjustably positioned onto or otherwise conform to the target bone, the cut guide comprising: a guide body forming the cut guide, the guide body including one or more guide members each sized, shaped or otherwise configured to constrain and guide a cutting tool along a respective cutting trajectory; and further comprising a plurality of landing members, each of the plurality of landing members including a respective coupling feature configured to removably couple to a landing site of the target bone, wherein the one or more guide members are configured to guide the cutting tool to cut the target bone along the respective cutting trajectory when the plurality of landing members are coupled to the landing site of the target bone, characterized by the coupling feature of each of the landing members includes a protruding portion configured to be end-user engaged into a respective coupling receptacle on the landing site of the target bone, the coupling receptacle including a recessed portion sized, shaped or otherwise configured to receive and secure the protruding portion of the respective coupling feature of each of the plurality of landing members. a cut guide configured to be adjustably positioned onto or otherwise conform to the target bone, the cut guide comprising: a guide body forming the cut guide, the guide body including one or more guide members each sized, shaped or otherwise configured to constrain and guide a cutting tool along a respective cutting trajectory; and further comprising a plurality of landing members, each of the plurality of landing members including a respective coupling feature configured to removably couple to a landing site of the target bone, a guide body forming the cut guide, the guide body including one or more guide members each sized, shaped or otherwise configured to constrain and guide a cutting tool along a respective cutting trajectory; and further comprising a plurality of landing members, each of the plurality of landing members including a respective coupling feature configured to removably couple to a landing site of the target bone, wherein the one or more guide members are configured to guide the cutting tool to cut the target bone along the respective cutting trajectory when the plurality of landing members are coupled to the landing site of the target bone, characterized by the coupling feature of each of the landing members includes a protruding portion configured to be end-user engaged into a respective coupling receptacle on the landing site of the target bone, the coupling receptacle including a recessed portion sized, shaped or otherwise configured to receive and secure the protruding portion of the respective coupling feature of each of the plurality of landing members.
A method (1400, 1600) for wireless communication, comprising: receiving (1402, 1602) peer-to-peer, P2P, configuration information from a base station (502, 702) at a first user equipment, UE, (504, 706), wherein the P2P configuration information specifies parameters for configuring a P2P connection between the first UE (504, 706) and a second UE (506, 708) according to an Evolved Universal Terrestrial Radio Access, E-UTRA, radio technology, and is received in at least one system information block, SIB, wherein receiving the P2P configuration information comprises receiving the at least one SIB in a periodic broadcast from the base station; and communicating directly with said second UE (506, 708) by the first UE (504, 706) based on the P2P configuration information. receiving (1402, 1602) peer-to-peer, P2P, configuration information from a base station (502, 702) at a first user equipment, UE, (504, 706), wherein the P2P configuration information specifies parameters for configuring a P2P connection between the first UE (504, 706) and a second UE (506, 708) according to an Evolved Universal Terrestrial Radio Access, E-UTRA, radio technology, and is received in at least one system information block, SIB, wherein receiving the P2P configuration information comprises receiving the at least one SIB in a periodic broadcast from the base station; and communicating directly with said second UE (506, 708) by the first UE (504, 706) based on the P2P configuration information.
A fusion protein comprising an NPP1 component fused to a targeting moiety, wherein the NPP1 component is a truncated NPP1 comprising the cysteine rich region and a catalytic domain having pyrophosphatase and/or phosphodiesterase activity but having the N-terminal cytosolic and the transmembrane domains removed, wherein the targeting moiety is capable of enhancing the targeting of the fusion protein to a site of calcification, and wherein said targeting moiety is fused to the C-terminus of the NPP1 component.
A method for use in a user equipment, UE, (203, 204, 501) for synchronizing a first user equipment, UE, with a second UE for peer-to-peer communication between first and second UEs being in proximity of one another in a cellular infrastructure comprising a plurality of radio access technologies, RATs and cells, the method comprising: - receiving, at the first UE, a synchronization message from at least one source or at least one RAT or at least one cell of the cellular infrastructure; - assembling, at the first UE, a message comprising a first list including information on the at least one source or the at least one RAT or at least one cell from which the first UE received the synchronization message; - including in the assembled message information on synchronization messages received from the different sources or different RATs or different cells, and on an averaging over the received synchronization messages. - transmitting, from the first UE, via the cellular infrastructure, the assembled message, to the second UE, and - initiating synchronized peer-to-peer communication with the second UE based on the received synchronization message from the at least one source or at least one RAT or the at least one cell of the cellular infrastructure. - receiving, at the first UE, a synchronization message from at least one source or at least one RAT or at least one cell of the cellular infrastructure; - assembling, at the first UE, a message comprising a first list including information on the at least one source or the at least one RAT or at least one cell from which the first UE received the synchronization message; - including in the assembled message information on synchronization messages received from the different sources or different RATs or different cells, and on an averaging over the received synchronization messages. - transmitting, from the first UE, via the cellular infrastructure, the assembled message, to the second UE, and - initiating synchronized peer-to-peer communication with the second UE based on the received synchronization message from the at least one source or at least one RAT or the at least one cell of the cellular infrastructure.
A method for producing a fibre-reinforced polymer melt by means of a single-screw extruder having a cylinder and a screw rotatably mounted therein, wherein a plastic material is supplied into the single-screw extruder via a first filling opening in the cylinder and is melted therein to a plastic melt, wherein remote from the first filling opening, with respect to conveying, a mass flow dmF/dt of one or more continuous fibre strands is introduced into the single-screw extruder via a second filling opening in the cylinder, wherein in the region of the second filling opening the plastic material is present as plastic melt, wherein the continuous fibre strands are inputted in dry state into the plastic melt and are impregnated with plastic melt, wherein the mixture of fibre strands and plastic melt is delivered as fibre-reinforced polymer melt out of a nozzle, situated at the end of the cylinder, remote with respect to conveying, wherein a screw is used which, remote from the second filling opening with respect to conveying, has a screw geometry such that the supplied continuous fibre strands exit from the nozzle substantially undamaged and impregnated with plastic melt, wherein a mass flow dmS/dt of plastic melt exiting from the nozzle and a mass flow dmP/dt of fibre-reinforced polymer melt, exiting from the nozzle, are present, wherein the mass flow dmF/dt and the mass flow dmS/dt are in a first ratio with respect to one another, in which the continuous fibre strands exiting from the nozzle are substantially entirely impregnated with plastic melt, wherein this first ratio represents a first mass flow target ratio which is kept substantially constant over predeterminable periods of time, and/or wherein the mass flow dmF/dt and the mass flow dmP/dt are in a second ratio with respect to one another, in which the continuous fibre strands exiting from the nozzle are substantially entirely impregnated with plastic melt, wherein the second ratio constitutes a second mass flow target ratio which is kept substantially constant over predeterminable periods of time.
Control method for an electromechanical element for positioning an element to be driven which is at least intermittently in contact with the electromechanical element, wherein in a step mode electrical voltage pulses are applied to the electromechanical element and each voltage pulse comprises at least two periods of time, wherein in one of the periods of time an on average slower time change of the electrical voltage and in the other period of time an on average faster time change of the electrical voltage takes place, and wherein at least in a part of the period of time of the on average slower time change of the electrical voltage, which defines a drive period, by static friction between the electromechanical element expanding or contracting in the driving direction and the driven element, the same is moved by and together with the electromechanical element, and wherein at least in a part of the period of time of the on average faster time change of the electrical voltage, which defines a relative movement period, by sliding friction between the electromechanical element contracting or expanding in a direction opposite to the drive direction and the element to be driven, a relative movement between electromechanical element and element to be driven takes place so that the element to be driven carries out a discrete step in the drive direction with each voltage pulse, and wherein the method further comprises the provision of a controller and a driver electrically connected thereto, characterized in that the controller transmits a continuous-time current (16, 17) to the driver, and the driver outputs a corresponding charging current to the electromechanical element electrically connected thereto, wherein the controller continuously adjusts the continuous-time current (16, 17) depending on the difference between the actual position and the target position of the element to be driven, and wherein the driver independently of the controller and depending on the voltage applied to the electromechanical element provides an electrical separation of the driver from the controller.
Agricultural machine comprising a central frame which supports at least two booms (12, 14), each boom having a working unit (16, 18) arranged thereon for processing harvested material, with support means (20, 22) being provided by which the working unit (16, 18) is held on the boom (12, 14), an adjustment device (24, 26) associated with the boom being further provided, which adjustment device is adapted to bring the working unit (16, 18) into a transport position and into a operating position with respect to the boom (12, 14), where, in its transport position, the working unit (16, 18) is raised from the ground and, in its operating position, it rests on the ground, the adjusting device (24, 26) comprising at least one hoisting cylinder (48, 50) that is supported directly or indirectly with respect to the associated boom (12, 14) and that is connected directly or indirectly to the working unit (16, 18) so that pressure applied to the hoisting cylinder (48, 50) will cause the working unit to be offset with at least one vertical component of movement relative to the boom, wherein the adjusting device (24, 26) comprises a lateral offset cylinder which is supported with respect to the working unit (16, 18) and to the boom (12, 14) and which, when pressurized, enables movement of the working unit (16, 18) with a horizontal component of movement, characterized in that said at least one hoisting cylinder (48, 50) has its first cylinder chamber (48a, 50a), which pressurizes said hoisting cylinder (48, 50) in the hoisting direction, connected to the first cylinder chamber of the lateral offset cylinder, which chamber acts in the direction of offset.
Method for distributing and using quantum secure cryptographic keys, that is to say QSKs, in a communication network, namely in a network having at least three network nodes, wherein at least two network nodes, forming a QKD association, in the network are connected to one another by way of a QKD connection, namely by way of a quantum key distribution connection for producing and using shared QSKs, which takes place using quantum mechanical effects, for the purpose of securing connections and for the purpose of encrypted data transmission, and wherein at least one network node of the network is a non-QKD-supported node, that is to say a network node that does not belong to a QKD association, characterized in that a completely disjunct connection of this kind is created for all non-QKD-supported nodes that are not already connected to a QKD association by way of two disjunct network paths, and in that a QKD association generates a number of first QSKs by means of which, through repeated XORing of single instances of these QSKs with one another and with a respective one of a plurality of further QSKs D[1,n] generated by this QKD association, single instances of the QSKs D[1,n] are successively distributed to non-QKD-supported nodes for the purpose of setting up quantum secure connections to other network nodes and for the purpose of encrypted data transmission via different network paths of their disjunct connection to the QKD association, wherein the generation and distribution of the QSKs takes place under the control of a central key management in cooperation with a local key management that is present at each network node.
An overhead bin of an aircraft, comprising: a first storage volume between a substantially rigid first shelf and a substantially rigid second shelf, the first storage volume having a first opening; a second storage volume above the first storage volume, the second storage volume between the second shelf and a top of the overhead bin, the second storage volume having a second opening, wherein the first opening and the second opening are accessed from a same side of the aircraft; a first door (440, 624, or 1012) moveably covering the first opening or at least one of a first door (440, 624, or 1012) moveably covering both the first opening and the second opening or a first door (440, 624, or 1012) and a second door (626, or 1008) moveably covering, respectively, the first opening and the second opening; at least one hand rail associated with at least one of the first storage volume or the second storage volume, said hand rail serving as a lip for inhibiting items from falling out of the first storage volume or the second storage volume when respective door is open, wherein said hand rail hangs outside the corresponding storage volume (217, 218). a first storage volume between a substantially rigid first shelf and a substantially rigid second shelf, the first storage volume having a first opening; a second storage volume above the first storage volume, the second storage volume between the second shelf and a top of the overhead bin, the second storage volume having a second opening, wherein the first opening and the second opening are accessed from a same side of the aircraft; a first door (440, 624, or 1012) moveably covering the first opening or at least one of a first door (440, 624, or 1012) moveably covering both the first opening and the second opening or a first door (440, 624, or 1012) and a second door (626, or 1008) moveably covering, respectively, the first opening and the second opening; at least one hand rail associated with at least one of the first storage volume or the second storage volume, said hand rail serving as a lip for inhibiting items from falling out of the first storage volume or the second storage volume when respective door is open, wherein said hand rail hangs outside the corresponding storage volume (217, 218).