A compound of general formula: in which: R 1 represents a *CH 2 -Z moiety, * indicating the point of attachment with the rest of the molecule, wherein Z is a hydrogen atom or C 1 -C 6 -alkyl- which is optionally substituted, identically or differently, with 1, 2, 3, or 4 R 7 groups; R 2 represents a in which * indicates the point of attachment with the rest of the molecule, and in which R 6a, R 6b, R 6c, R 6d represent, independently from each other, a hydrogen or halogen atom, or a -CN, C 1 -C 6 -alkyl-, C 1 -C 6 -alkoxy-, halo-C 1 -C 6 -alkyl-, R(R')N-C 1 -C 6 -alkyl-, HO-C 1 -C 6 -alkyl-, C 1 -C 6 -alkoxy-C 1 -C 6 -alkyl-, halo-C 1 -C 6 -alkoxy-C 1 -C 6 -alkyl-, -OR group; and R 6e represents a cyclopropyl-group being optionally substituted, identically or differently, with 1, 2, 3 or 4 groups selected from: hydrogen, halogen, -OH, -CN, C 1 -C 6 -alkyl-, -C 1 -C 6 -alkoxy, halo-C 1 -C 6 -alkyl-; R 3 represents a hydrogen atom or a halogen atom, or a -CN, C 1 -C 6 -alkyl-, aryl-C 1 -C 6 -alkyl-, heteroaryl-C 1 -C 6 -alkyl-, C 3 -C 6 -cycloalkyl-, 3- to 7-membered heterocycloalkyl-, C 4 -C 8 -cycloalkenyl-, aryl-, -C 1 -C 6 -alkyl-aryl, -C 1 -C 6 -alkyl-heteroaryl, heteroaryl- or a -NH 2 group; said C 1 -C 6 -alkyl-, aryl-C 1 -C 6 -alkyl-, heteroaryl-C 1 -C 6 -alkyl-, C 3 -C 6 -cycloalkyl-, 3- to 7-membered heterocycloalkyl-, C 4 -C 8 -cycloalkenyl-, aryl-, -C 1 -C 6 -alkyl-aryl, -C 1 -C 6 -alkyl-heteroaryl, heteroaryl-, -NH 2 group being optionally substituted, identically or differently, with 1, 2, 3 or 4 R 8 groups R 4 is a hydrogen atom or a C 1 -C 6 -alkyl- or aryl-group; R 5 represents a HO-, -NH 2, C 1 -C 6 -alkyl-, -C 1 -C 6 -alkyl-N C(=O)R, -C 1 -C 6 -alkyl-C(=O)N R, -C 1 -C 6 -alkyl-C(=O)OR, halo-C 1 -C 6 -alkyl-, R(R')N-C 1 -C 6 -alkyl-, HO-C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy-C 1 -C 6 -alkyl-, -C(=O)N R, -C(=O)N R', -C(=O)OR, -N R' or a -N C(=O)N R' group; R 7 represents a hydrogen or halogen atom or a -CN, HO-, C 1 -C 6 -alkoxy-, C 1 -C 6 -alkyl-, halo-C 1 -C 6 -alkyl-, -N R', -N C(=O)R, -N C(=O)R', -OR or -O(C=O)R group; R 8 represents a hydrogen or halogen atom or a -CN, -C(=O)N R, -C(=O)N R', -N R', -N C(=O)N R', -N C(=O)N(R')R"; R, R' and R" are, independently from each other, a hydrogen atom or a C 1 -C 6 -alkyl- group; or a stereoisomer, a tautomer, an N-oxide, a hydrate, a solvate, or a salt thereof, or a mixture of same. R 1 represents a *CH 2 -Z moiety, * indicating the point of attachment with the rest of the molecule, wherein Z is a hydrogen atom or C 1 -C 6 -alkyl- which is optionally substituted, identically or differently, with 1, 2, 3, or 4 R 7 groups; R 2 represents a in which * indicates the point of attachment with the rest of the molecule, and in which R 6a, R 6b, R 6c, R 6d represent, independently from each other, a hydrogen or halogen atom, or a -CN, C 1 -C 6 -alkyl-, C 1 -C 6 -alkoxy-, halo-C 1 -C 6 -alkyl-, R(R')N-C 1 -C 6 -alkyl-, HO-C 1 -C 6 -alkyl-, C 1 -C 6 -alkoxy-C 1 -C 6 -alkyl-, halo-C 1 -C 6 -alkoxy-C 1 -C 6 -alkyl-, -OR group; and R 6e represents a cyclopropyl-group being optionally substituted, identically or differently, with 1, 2, 3 or 4 groups selected from: hydrogen, halogen, -OH, -CN, C 1 -C 6 -alkyl-, -C 1 -C 6 -alkoxy, halo-C 1 -C 6 -alkyl-; R 6a, R 6b, R 6c, R 6d represent, independently from each other, a hydrogen or halogen atom, or a -CN, C 1 -C 6 -alkyl-, C 1 -C 6 -alkoxy-, halo-C 1 -C 6 -alkyl-, R(R')N-C 1 -C 6 -alkyl-, HO-C 1 -C 6 -alkyl-, C 1 -C 6 -alkoxy-C 1 -C 6 -alkyl-, halo-C 1 -C 6 -alkoxy-C 1 -C 6 -alkyl-, -OR group; and R 6e represents a cyclopropyl-group being optionally substituted, identically or differently, with 1, 2, 3 or 4 groups selected from: hydrogen, halogen, -OH, -CN, C 1 -C 6 -alkyl-, -C 1 -C 6 -alkoxy, halo-C 1 -C 6 -alkyl-; R 3 represents a hydrogen atom or a halogen atom, or a -CN, C 1 -C 6 -alkyl-, aryl-C 1 -C 6 -alkyl-, heteroaryl-C 1 -C 6 -alkyl-, C 3 -C 6 -cycloalkyl-, 3- to 7-membered heterocycloalkyl-, C 4 -C 8 -cycloalkenyl-, aryl-, -C 1 -C 6 -alkyl-aryl, -C 1 -C 6 -alkyl-heteroaryl, heteroaryl- or a -NH 2 group; said C 1 -C 6 -alkyl-, aryl-C 1 -C 6 -alkyl-, heteroaryl-C 1 -C 6 -alkyl-, C 3 -C 6 -cycloalkyl-, 3- to 7-membered heterocycloalkyl-, C 4 -C 8 -cycloalkenyl-, aryl-, -C 1 -C 6 -alkyl-aryl, -C 1 -C 6 -alkyl-heteroaryl, heteroaryl-, -NH 2 group being optionally substituted, identically or differently, with 1, 2, 3 or 4 R 8 groups R 4 is a hydrogen atom or a C 1 -C 6 -alkyl- or aryl-group; R 5 represents a HO-, -NH 2, C 1 -C 6 -alkyl-, -C 1 -C 6 -alkyl-N C(=O)R, -C 1 -C 6 -alkyl-C(=O)N R, -C 1 -C 6 -alkyl-C(=O)OR, halo-C 1 -C 6 -alkyl-, R(R')N-C 1 -C 6 -alkyl-, HO-C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy-C 1 -C 6 -alkyl-, -C(=O)N R, -C(=O)N R', -C(=O)OR, -N R' or a -N C(=O)N R' group; R 7 represents a hydrogen or halogen atom or a -CN, HO-, C 1 -C 6 -alkoxy-, C 1 -C 6 -alkyl-, halo-C 1 -C 6 -alkyl-, -N R', -N C(=O)R, -N C(=O)R', -OR or -O(C=O)R group; R 8 represents a hydrogen or halogen atom or a -CN, -C(=O)N R, -C(=O)N R', -N R', -N C(=O)N R', -N C(=O)N(R')R"; R, R' and R" are, independently from each other, a hydrogen atom or a C 1 -C 6 -alkyl- group;