A clamping block for receiving a parting blade having an internal coolant guide, wherein the clamping block has: a parting blade seat having a contact face for a lateral face of the parting blade, and clamping jaws (112, 113) which for chucking the parting blade on the clamping block extend on opposite longitudinal sides of the contact face; wherein the clamping block is configured for receiving the parting blade in a first installation direction in which the parting blade by way of a cutter portion projects from a first end side of the clamping block, and in a second installation direction in which the parting blade by way of the cutter portion projects from a second end side of the clamping block that is opposite the first end side; wherein a first coolant exit opening for transferring coolant from the clamping block into the parting blade when installing in the first installation direction, and a second coolant exit opening for transferring coolant from the clamping block into the parting blade when installing in the second installation direction, are configured on the contact face; characterized in that the clamping block has at least two different first coolant entry openings (122, 123, 124) and a first internal coolant duct structure by way of which the first coolant exit opening is connectable so as to communicate with the at least two different first coolant entry openings (122, 123, 124) of the clamping block is configured in the clamping block, and wherein the clamping block has at least two different second coolant entry openings (132, 133, 134) and a second internal coolant duct structure by way of which the second coolant exit opening is connectable so as to communicate with the at least two different second coolant entry openings (132, 133, 134) of the clamping block is configured in the clamping block. a parting blade seat having a contact face for a lateral face of the parting blade, and clamping jaws (112, 113) which for chucking the parting blade on the clamping block extend on opposite longitudinal sides of the contact face; wherein the clamping block is configured for receiving the parting blade in a first installation direction in which the parting blade by way of a cutter portion projects from a first end side of the clamping block, and in a second installation direction in which the parting blade by way of the cutter portion projects from a second end side of the clamping block that is opposite the first end side; wherein a first coolant exit opening for transferring coolant from the clamping block into the parting blade when installing in the first installation direction, and a second coolant exit opening for transferring coolant from the clamping block into the parting blade when installing in the second installation direction, are configured on the contact face; characterized in that the clamping block has at least two different first coolant entry openings (122, 123, 124) and a first internal coolant duct structure by way of which the first coolant exit opening is connectable so as to communicate with the at least two different first coolant entry openings (122, 123, 124) of the clamping block is configured in the clamping block, and wherein the clamping block has at least two different second coolant entry openings (132, 133, 134) and a second internal coolant duct structure by way of which the second coolant exit opening is connectable so as to communicate with the at least two different second coolant entry openings (132, 133, 134) of the clamping block is configured in the clamping block.