mhurhangee/ep-ind-claims huggingface dataset:
A gene expression system comprising: (a) an expression enhancer sequence derived from the RNA-2 genome segment of a Comoviridae bipartite RNA virus, in which a translation initiation site in the RNA-2 genome segment has been mutated, wherein the wild-type RNA2 genome segment of the Comoviridae virus encodes two carboxy coterminal proteins through two different translation initiation sites located in the same triplet reading frame, wherein the mutated initiation site is the first of these two initiation sites and corresponds to the initiation site at position 161 in the wild-type RNA-2 segment of CPMV; wherein expression enhancer sequence either: (i) comprises at least a 200 nucleotide sequence of the comoviral RNA-2 genome segment which includes the mutated initiation site, or (ii) has at least 70% identity to nucleotides 1 to 507 of the CPMV RNA-2 genome segment sequence shown in Table 1, and wherein the initiation site at position 161 in the wild-type CPMV RNA-2 genome segment has been mutated and (b) a heterologous gene encoding a protein of interest, wherein the gene encoding the protein of interest is located downstream of the enhancer sequence and is operably linked to promoter and terminator sequences. (a) an expression enhancer sequence derived from the RNA-2 genome segment of a Comoviridae bipartite RNA virus, in which a translation initiation site in the RNA-2 genome segment has been mutated, wherein the wild-type RNA2 genome segment of the Comoviridae virus encodes two carboxy coterminal proteins through two different translation initiation sites located in the same triplet reading frame, wherein the mutated initiation site is the first of these two initiation sites and corresponds to the initiation site at position 161 in the wild-type RNA-2 segment of CPMV; wherein expression enhancer sequence either: (i) comprises at least a 200 nucleotide sequence of the comoviral RNA-2 genome segment which includes the mutated initiation site, or (ii) has at least 70% identity to nucleotides 1 to 507 of the CPMV RNA-2 genome segment sequence shown in Table 1, and wherein the initiation site at position 161 in the wild-type CPMV RNA-2 genome segment has been mutated and (i) comprises at least a 200 nucleotide sequence of the comoviral RNA-2 genome segment which includes the mutated initiation site, or (ii) has at least 70% identity to nucleotides 1 to 507 of the CPMV RNA-2 genome segment sequence shown in Table 1, and wherein the initiation site at position 161 in the wild-type CPMV RNA-2 genome segment has been mutated and (b) a heterologous gene encoding a protein of interest,
A method for purifying a recombinant protein from a gram-negative bacterial host cell sample or extract thereof wherein said host cell expresses a recombinant protein and a recombinant disulphide isomerase DsbC; wherein the method comprises: a) adjusting the pH of the host cell sample or extract thereof to a pH of 5 or less to precipitate the recombinant disulphide isomerase; and b) separating precipitated recombinant disulphide isomerase from the recombinant protein to produce a recombinant protein sample. a) adjusting the pH of the host cell sample or extract thereof to a pH of 5 or less to precipitate the recombinant disulphide isomerase; and b) separating precipitated recombinant disulphide isomerase from the recombinant protein to produce a recombinant protein sample.
A method comprising: identifying, by a computing device and based at least in part on parsing source code of a layout file that defines a graphical user interface for an application, a plurality of data binding expressions, wherein each of the plurality of data binding expressions defines a respective data binding comprising an association between a user interface element of the graphical user interface and one or more properties of a model object of a model for the application; determining, by the computing device, based at least in part on the plurality of data binding expressions, one or more dependencies between each of the plurality of data binding expressions by determining which data binding expressions of the layout file have terms that depend on the same properties of a particular model object; generating, by the computing device, based at least in part on the one or more dependencies, additional source code for updating at least one respective data binding defined by the plurality of data binding expressions in response to a change to at least one property of the model object; and generating, by the computing device, the application comprising machine-executable code that is based at least in part on the source code of the layout file, the model object, and the additional source code. identifying, by a computing device and based at least in part on parsing source code of a layout file that defines a graphical user interface for an application, a plurality of data binding expressions, wherein each of the plurality of data binding expressions defines a respective data binding comprising an association between a user interface element of the graphical user interface and one or more properties of a model object of a model for the application; determining, by the computing device, based at least in part on the plurality of data binding expressions, one or more dependencies between each of the plurality of data binding expressions by determining which data binding expressions of the layout file have terms that depend on the same properties of a particular model object; generating, by the computing device, based at least in part on the one or more dependencies, additional source code for updating at least one respective data binding defined by the plurality of data binding expressions in response to a change to at least one property of the model object; and generating, by the computing device, the application comprising machine-executable code that is based at least in part on the source code of the layout file, the model object, and the additional source code.
A method for imaging an epithelial tissue of a subject, comprising: (a) providing a portable device comprising an optical probe, a relay lens assembly, and a mobile lens in optical communication with the optical probe, wherein the optical probe comprises an optical element disposed adjacent to the epithelial tissue, and wherein the mobile lens is movable with respect to the optical element; (b) using the optical probe to transmit pulses of a single beam of light from a light source through the mobile lens towards a surface of the epithelial tissue, wherein while the pulses of the single beam of light are transmitted, the mobile lens undergoes movement within the portable device relative to the optical element to focus the pulses of the single beam of light within a plurality of different focal planes within the epithelial tissue, and wherein the pulses of the single beam of light, upon contacting the epithelial tissue, generate signals indicative of an intrinsic property of the epithelial tissue across the plurality of different focal planes; (c) using a collection module to collect at least a subset of the signals generated across the plurality of different focal planes upon the pulses of the single beam of light being transmitted from the light source, wherein the optical probe comprises a telecentric objective that maintains a constant numerical aperture; and (d) using a programmed computer processor to process the subset of the signals to generate a depth profile of the epithelial tissue. (a) providing a portable device comprising an optical probe, a relay lens assembly, and a mobile lens in optical communication with the optical probe, wherein the optical probe comprises an optical element disposed adjacent to the epithelial tissue, and wherein the mobile lens is movable with respect to the optical element; (b) using the optical probe to transmit pulses of a single beam of light from a light source through the mobile lens towards a surface of the epithelial tissue, wherein while the pulses of the single beam of light are transmitted, the mobile lens undergoes movement within the portable device relative to the optical element to focus the pulses of the single beam of light within a plurality of different focal planes within the epithelial tissue, and wherein the pulses of the single beam of light, upon contacting the epithelial tissue, generate signals indicative of an intrinsic property of the epithelial tissue across the plurality of different focal planes; (c) using a collection module to collect at least a subset of the signals generated across the plurality of different focal planes upon the pulses of the single beam of light being transmitted from the light source, wherein the optical probe comprises a telecentric objective that maintains a constant numerical aperture; and (d) using a programmed computer processor to process the subset of the signals to generate a depth profile of the epithelial tissue.
A communication event notification method, comprising: learning, by a central device, of a communication event; receiving, by the central device, position coordinates or longitude and latitude of a wearable device reported by a positioning device and position coordinates or longitude and latitude of bridge devices; determining (S 102), by the central device, at least one bridge device according to the position coordinates or longitude and latitude of the wearable device and the position coordinates or longitude and latitude of the bridge devices; sending (S 103), by the central device, notification information according to the communication event to the determined at least one bridge device. learning, by a central device, of a communication event; receiving, by the central device, position coordinates or longitude and latitude of a wearable device reported by a positioning device and position coordinates or longitude and latitude of bridge devices; determining (S 102), by the central device, at least one bridge device according to the position coordinates or longitude and latitude of the wearable device and the position coordinates or longitude and latitude of the bridge devices; sending (S 103), by the central device, notification information according to the communication event to the determined at least one bridge device.
A Transforming Growth Factor beta (TGFβ) antagonist for use in treating cancer in combination with capecitabine and ixabepilone in a subject, wherein said TGFβ antagonist enhances the efficacy of capecitabine and ixabepilone in treating said cancer.
A method for authenticating an item, comprising: providing the item including a polymer substrate having a first surface and a second surface, the polymer substrate comprising a polymer material and a doping material, the polymer material and the doping material configured to transmit radiation laterally through the polymer substrate through a wave guided propagation mechanism between the first surface and the second surface, and the doping material capable of scattering radiation and absorbing radiation of at least one specific wavelength to generate a spectral signature in a spectral band of wavelengths of the transmitted radiation; irradiating the item with incident radiation through a clear polymer window of the item at a first point, characterized by a spectral band of wavelengths spanning a band of wavelengths including the at least one specific wavelength absorbed and scattered by the doping material; detecting at a second point located laterally a distance from the first point the spectral signature after the radiation is transmitted laterally through the polymer substrate through the wave guided propagation mechanism through total internal reflection between the first surface and the second surface; and determining a code associated with the spectral signature, and comparing the determined code to a reference code. providing the item including a polymer substrate having a first surface and a second surface, the polymer substrate comprising a polymer material and a doping material, the polymer material and the doping material configured to transmit radiation laterally through the polymer substrate through a wave guided propagation mechanism between the first surface and the second surface, and the doping material capable of scattering radiation and absorbing radiation of at least one specific wavelength to generate a spectral signature in a spectral band of wavelengths of the transmitted radiation; irradiating the item with incident radiation through a clear polymer window of the item at a first point, characterized by a spectral band of wavelengths spanning a band of wavelengths including the at least one specific wavelength absorbed and scattered by the doping material; detecting at a second point located laterally a distance from the first point the spectral signature after the radiation is transmitted laterally through the polymer substrate through the wave guided propagation mechanism through total internal reflection between the first surface and the second surface; and determining a code associated with the spectral signature, and comparing the determined code to a reference code.
A method comprising: generating a codeword based on a segmentation transform and a Polarization-Adjusted Convolutional, PAC, code that comprises an outer convolutional code and a polar code, and based on separate encoding of respective different segments of convolutionally encoded input bits according to the polar code, each segment of the respective segments comprising a plurality of the convolutionally encoded input bits for which the separate encoding of the segment is independent of the separate encoding of other segments, wherein the segmentation transform comprises interleaving the input bits before convolutional encoding according to the outer convolutional code or combining convolutionally encoded input bits for the separate encoding of a segment; transmitting the codeword; wherein the outer convolutional code comprises a non-zero initial state and state feedback. generating a codeword based on a segmentation transform and a Polarization-Adjusted Convolutional, PAC, code that comprises an outer convolutional code and a polar code, and based on separate encoding of respective different segments of convolutionally encoded input bits according to the polar code, each segment of the respective segments comprising a plurality of the convolutionally encoded input bits for which the separate encoding of the segment is independent of the separate encoding of other segments, wherein the segmentation transform comprises interleaving the input bits before convolutional encoding according to the outer convolutional code or combining convolutionally encoded input bits for the separate encoding of a segment; transmitting the codeword; wherein the outer convolutional code comprises a non-zero initial state and state feedback.
A conveying facility with roller-guided conveying elements, comprising in each case a basis body, several rollers (3a-3d) which are rotatably mounted on the basis body at two sides which lie opposed to one another, wherein the basis body is arranged between the rollers (3a-3d) attached at both sides, and a holding member which is arranged on the basis body and is for holding an object to be conveyed, as well as with a longitudinal guidance body (51, 151, 251) forming a guide channel (52, 152, 252), along which guide channel the conveying elements are rollingly movable, wherein the conveying elements with the rollers (3a-3d) are designed in a manner such that a section of the conveying elements, with in each case at least one roller (3a-3d) of the two sides of the basis body is rollingly movable in the guide channel of the longitudinal guidance body, characterised in that the rollers (3a-3d) in each case are two rollers (3a-3) which are arranged oppositely and equally offset in a crosswise manner on the two sides on the basis body. characterised in that the rollers (3a-3d) in each case are two rollers (3a-3) which are arranged oppositely and equally offset in a crosswise manner on the two sides on the basis body.
Drive turbine (1; 10) for a rotary atomizer, with a) a turbine rotor (17, 25, 26, 27), b) a rotatably supported turbine shaft (2; 17) with an assembly option to attach a bell cup (3; 39), and c) at least one drive turbine wheel (4-6; 25-27) with a plurality of turbine blades, wherein the turbine blades of the drive turbine wheel (4-6; 25-27) have a drive fluid flowing over them during operation in order to drive the turbine rotor (17, 25, 26, 27), d) wherein the drive turbine wheel (4-6; 25-27) is designed for an axial flow of the drive fluid over the turbine blades, characterized e) in that a plurality of drive turbine wheels (4-6; 25-27) are axially arranged one behind the other, wherein the individual drive turbine wheels (4-6; 25-27) each have a plurality of turbine blades, which are designed for an axial flow of the drive fluid over the turbine blades, and f) in that the drive turbine wheels (4-6; 25-27) extend in an axial direction together over a certain drive length and are arranged in a turbine housing with a certain outer diameter, wherein the ratio of the outer diameter of the turbine housing and the drive length is greater than 0.4 and less than 1, and g) in that the drive turbine wheels (4-6; 25-27) extend in an axial direction together over a certain drive length and are surrounded by stator rings (7, 8; 28, 29) with a certain maximum outer diameter, wherein the ratio of the outer diameter of the stator rings (7, 8; 28, 29) and the drive length is greater than 0.4 and less than 0.5. a) a turbine rotor (17, 25, 26, 27), b) a rotatably supported turbine shaft (2; 17) with an assembly option to attach a bell cup (3; 39), and c) at least one drive turbine wheel (4-6; 25-27) with a plurality of turbine blades, wherein the turbine blades of the drive turbine wheel (4-6; 25-27) have a drive fluid flowing over them during operation in order to drive the turbine rotor (17, 25, 26, 27), d) wherein the drive turbine wheel (4-6; 25-27) is designed for an axial flow of the drive fluid over the turbine blades, e) in that a plurality of drive turbine wheels (4-6; 25-27) are axially arranged one behind the other, wherein the individual drive turbine wheels (4-6; 25-27) each have a plurality of turbine blades, which are designed for an axial flow of the drive fluid over the turbine blades, and f) in that the drive turbine wheels (4-6; 25-27) extend in an axial direction together over a certain drive length and are arranged in a turbine housing with a certain outer diameter, wherein the ratio of the outer diameter of the turbine housing and the drive length is greater than 0.4 and less than 1, and g) in that the drive turbine wheels (4-6; 25-27) extend in an axial direction together over a certain drive length and are surrounded by stator rings (7, 8; 28, 29) with a certain maximum outer diameter, wherein the ratio of the outer diameter of the stator rings (7, 8; 28, 29) and the drive length is greater than 0.4 and less than 0.5.
A key for a keyboard comprising: a keycap, wherein the keycap includes a pocket on the top side of the key, and the pocket includes: a protective layer; and an active element (136, 138), wherein the height of the protective layer and the active element is less than six, 6, millimeters in height. a protective layer; and an active element (136, 138), wherein the height of the protective layer and the active element is less than six, 6, millimeters in height.
An electrical contact assembly, comprising: a crossbar; a pivot pin mounted in the crossbar; a contact arm pivotally mounted on the pivot pin and rotatable about a pivot axis; a moveable electrical contact spaced from the pivot axis on a first arm portion of the contact arm; and a spring assembly coupled between the crossbar and the contact arm at a connection location spaced from the pivot axis, characterized by the spring assembly including a spring and a clevis pin wherein an end of the clevis pin extends through the spring and is received in a pivot recess in the crossbar. a crossbar; a pivot pin mounted in the crossbar; a contact arm pivotally mounted on the pivot pin and rotatable about a pivot axis; a moveable electrical contact spaced from the pivot axis on a first arm portion of the contact arm; and a spring assembly coupled between the crossbar and the contact arm at a connection location spaced from the pivot axis, characterized by the spring assembly including a spring and a clevis pin
An auxiliary power system for a vehicle having a main engine and a main air conditioning system, comprising an auxiliary internal combustion engine having a starter; an auxiliary current generator driven by said auxiliary engine and connectable to a battery of the vehicle; an auxiliary cooling circuit having a compressor driven by said auxiliary engine; control means (41, 50) comprising comparing means (41, 57) connected to said battery to determine the voltage of the battery; and further means for activating said starter of said auxiliary engine; said control means generating an enabling signal to activate said starter of said auxiliary engine in response to a voltage value of said battery below a reference value; means for measurin time from the start of the auxiliary engine; means for turning off said auxiliary engine, said control means generating a control signal, for said means for turning off said auxiliary engine, when the measured time reaches a predetermined charge time; said control means providing for an automatic recharge of said battery even when said main engine is turned off.
A machine for automatically inflating gas cushions, notably air cushions, the cushions comprising two walls (21, 22) made of plastic linked together on their periphery, which thus define a closed space, characterized in that it comprises a source of pressurized gas, two jaws (1,2) placed movably on a frame, each of said jaws consisting of a body (1,3) each having a flat face (4, 10) of substantially the same shape and same surface area, said faces being able to come against one another so as to clamp between them the walls of a cushion, each jaw comprising suction means (6, 7) leading onto its flat face, a first jaw having inside its body a hollow needle that can move relative to the body and being able, in a certain position, to have its point outside the surface of the flat face, a second jaw having, inside its body, a heating element which can, when the two jaws clamp between them the two walls of a cushion, heat-seal the two walls together over a certain portion of their contact surface.
Herbicidal compositions, comprising, as herbicidally active components, A) triallate (component A), B) picolinafen (component B). A) triallate (component A), B) picolinafen (component B).