A polymeric composite particle comprising a) a porous polymeric core particle comprising a polymerized product formed by providing a poly(propylene glycol)-entrained polymerized product of a reaction mixture comprising: i) a first phase comprising either 1) water and a polysaccharide dissolved in the water; or 2) a surfactant and a compound of Formula HO(-CH 2 -CH -CH 2 -O) n -H wherein n is an integer equal to at least 1, or a mixture thereof; and ii) a second phase dispersed in the first phase, wherein a volume of the first phase is greater than a volume of the second phase and wherein the second phase comprises 1) a first monomer composition comprising a monomer of Formula CH 2 =C(R 1)- -O[-CH 2 -CH 2 -O] p - -C(R 1)=CH 2 wherein the monomer of Formula is not miscible with the first phase; p is an integer is no greater than 30; R 1 is hydrogen or alkyl; and 2) a poly(propylene glycol) having a weight average molecular weight of at least 500 grams/mole, separating the poly(propylene glycol)-entrained polymerized product from the first phase, and removing the poly(propylene glycol) from the poly(propylene glycol)-entrained polymerized product to provide the porous polymeric core; b) a biologically active agent positioned within the porous polymeric core, wherein the biologically active agent is not covalently bonded to the porous polymeric core; and c) a coating layer around the porous polymeric core particle, wherein the coating layer comprises a thermoplastic polymer, a wax, or a mixture thereof. a) a porous polymeric core particle comprising a polymerized product formed by providing a poly(propylene glycol)-entrained polymerized product of a reaction mixture comprising: i) a first phase comprising either 1) water and a polysaccharide dissolved in the water; or 2) a surfactant and a compound of Formula HO(-CH 2 -CH -CH 2 -O) n -H wherein n is an integer equal to at least 1, or a mixture thereof; and ii) a second phase dispersed in the first phase, wherein a volume of the first phase is greater than a volume of the second phase and wherein the second phase comprises 1) a first monomer composition comprising a monomer of Formula CH 2 =C(R 1)- -O[-CH 2 -CH 2 -O] p - -C(R 1)=CH 2 wherein the monomer of Formula is not miscible with the first phase; p is an integer is no greater than 30; R 1 is hydrogen or alkyl; and 2) a poly(propylene glycol) having a weight average molecular weight of at least 500 grams/mole, separating the poly(propylene glycol)-entrained polymerized product from the first phase, and removing the poly(propylene glycol) from the poly(propylene glycol)-entrained polymerized product to provide the porous polymeric core; i) a first phase comprising either 1) water and a polysaccharide dissolved in the water; or 2) a surfactant and a compound of Formula HO(-CH 2 -CH -CH 2 -O) n -H wherein n is an integer equal to at least 1, or a mixture thereof; and 1) water and a polysaccharide dissolved in the water; or 2) a surfactant and a compound of Formula HO(-CH 2 -CH -CH 2 -O) n -H ii) a second phase dispersed in the first phase, wherein a volume of the first phase is greater than a volume of the second phase and wherein the second phase comprises 1) a first monomer composition comprising a monomer of Formula CH 2 =C(R 1)- -O[-CH 2 -CH 2 -O] p - -C(R 1)=CH 2 wherein the monomer of Formula is not miscible with the first phase; p is an integer is no greater than 30; R 1 is hydrogen or alkyl; and 2) a poly(propylene glycol) having a weight average molecular weight of at least 500 grams/mole, 1) a first monomer composition comprising a monomer of Formula CH 2 =C(R 1)- -O[-CH 2 -CH 2 -O] p - -C(R 1)=CH 2 wherein the monomer of Formula is not miscible with the first phase; p is an integer is no greater than 30; R 1 is hydrogen or alkyl; and p is an integer is no greater than 30; R 1 is hydrogen or alkyl; and 2) a poly(propylene glycol) having a weight average molecular weight of at least 500 grams/mole, b) a biologically active agent positioned within the porous polymeric core, wherein the biologically active agent is not covalently bonded to the porous polymeric core; and c) a coating layer around the porous polymeric core particle, wherein the coating layer comprises a thermoplastic polymer, a wax, or a mixture thereof.