mhurhangee/ep-ind-claims huggingface dataset:
Method of identifying T cell epitopes from an antigen of interest, comprising: a) expressing at least one candidate antigen selected from the group, consisting of a candidate self-antigen and a candidate foreign antigen in an antigen presenting cell that expresses a defined HLA molecule; b) utilizing an affinity-based algorithmic prediction to identify a plurality of peptides from said candidate antigen that are predicted to bind to said defined HLA molecule to provide predicted peptides; c) synthesizing said predicted peptides and forming complexes of said synthesized predicted peptides with said defined HLA molecule to generate predicted peptide:defined HLA molecule complexes; d) contacting said antigen-presenting cells with T cells that are not tolerant to said predicted peptide:defined HLA molecule complexes to provide induced T cells; and e) identifying T cells reactive with said predicted peptide:defined HLA molecule complexes by contacting said induced T cells with said predicted peptide:defined HLA molecule complexes to identify T cells reactive with said complexes. a) expressing at least one candidate antigen selected from the group, consisting of a candidate self-antigen and a candidate foreign antigen in an antigen presenting cell that expresses a defined HLA molecule; b) utilizing an affinity-based algorithmic prediction to identify a plurality of peptides from said candidate antigen that are predicted to bind to said defined HLA molecule to provide predicted peptides; c) synthesizing said predicted peptides and forming complexes of said synthesized predicted peptides with said defined HLA molecule to generate predicted peptide:defined HLA molecule complexes; d) contacting said antigen-presenting cells with T cells that are not tolerant to said predicted peptide:defined HLA molecule complexes to provide induced T cells; and e) identifying T cells reactive with said predicted peptide:defined HLA molecule complexes by contacting said induced T cells with said predicted peptide:defined HLA molecule complexes to identify T cells reactive with said complexes.
A squeeze packing, having on at least one arbitrary portion of an endless ring finished to predetermined dimensions, a cut surface (5, 6) forming a three-dimensional curved surface shape extending diagonally so as to form a predetermined angle θ with respect to a radial direction of the ring, having a substantially S-shaped profile in front or reverse side view, characterized in that the cut surface (5, 6) has an arcuate shape that decreases in height from the front side to the reverse side of the ring at a first cross section (a); a shape that approximates a straight line in a substantially horizontal direction from the front side to the reverse side of the ring at a second cross section (b) located circumferentially further along the ring relative to said first cross section (a); and an arcuate shape that rises from the front side to the reverse side of the ring at a third cross section (c) located circumferentially further along the ring relative to said second cross section (b); said cut surface (5, 6) being such that no relative movement is possible at the cut portion either in the circumferential direction of the ring nor in a front side-to-reverse side or reverse side-to-front side direction.
Apparatus for non-invasively evaluating endothelial activity in a patient, particularly for indicating the presence of an endothelial dysfunction condition, comprising; an occluding cuff for applying an occluding pressure to a predetermined part of an arm or leg of the patient to occlude blood flow therein for a predetermined time period; a monitoring digit-probe for monitoring a digit of said arm or leg for changes in the peripheral arterial tone therein before and after the application of said occluding pressure to the arm or leg of the patient; and a processor designed for utilizing any detected changes in said peripheral arterial tone, including changes in the dynamic signal time-course following removal of the occluding pressure, for evaluating endothelial activity in the patient, and particularly for indicating the presence of an endothelial dysfunction condition.
In-wall installation device for single-lever mixing taps having a cartridge and an outlet, which is connected to a mixing chamber in the cartridge, to which a hot and a cold water connection (2, 3) are connected and which is arranged in a base member, wherein the supply from the hot and the cold water connection (2, 3) can be adjusted using the cartridge and wherein the cartridge is arranged in an adapter, which can be installed in the base member in a state rotated at angles of 90°, characterised in that the adapter at the end thereof facing away from the cartridge has an external square member, which in the mounted state of the adapter engages in an internal square member in the base member.
A method for performing Transmission Time Interval, TTI, bundling in a wireless access system, the method comprising: transmitting, by a user equipment, UE,, first uplink data via bundled subframes; receiving a first Physical Hybrid-Automatic Repeat request, HARQ, Indicator Channel, PHICH, corresponding to the first uplink data, in a 4 th subframe from a last subframe of the bundled subframes; transmitting, by the UE after the first PHICH, second uplink data that is retransmission of the first uplink data via bundled subframes; and receiving a second PHICH corresponding to the second uplink data, wherein a PHICH period is changed from 12 TTIs to 16 TTIs after receiving the second PHICH, based on a higher layer signaled parameter related to a change of the PHICH period, and wherein the first uplink data is transmitted via 8 bundled subframes and the second uplink data is transmitted via 4 bundled subframes. transmitting, by a user equipment, UE,, first uplink data via bundled subframes; receiving a first Physical Hybrid-Automatic Repeat request, HARQ, Indicator Channel, PHICH, corresponding to the first uplink data, in a 4 th subframe from a last subframe of the bundled subframes; transmitting, by the UE after the first PHICH, second uplink data that is retransmission of the first uplink data via bundled subframes; and receiving a second PHICH corresponding to the second uplink data, wherein a PHICH period is changed from 12 TTIs to 16 TTIs after receiving the second PHICH, based on a higher layer signaled parameter related to a change of the PHICH period, and wherein the first uplink data is transmitted via 8 bundled subframes and the second uplink data is transmitted via 4 bundled subframes.
Device for electrical interconnection of cells of a battery pack by means of cell connectors, characterized in that a plurality of cell connectors for connection of at least two cell poles are fitted on a mounting plate, electrically isolated from one another, wherein the mounting plate is fitted with a stamped grid of cell connectors and at least one conductor track which is connected integrally thereto and is in contrast narrow.
A method at a network node, comprising: identifying a fixed periodic pattern to be used for scheduling a half-duplex, HD, user equipment, UE, the fixed periodic pattern defining a sequence of at least one downlink subframe, then at least one guard period, and then at least one uplink subframe, wherein the UE is configured for HD frequency division duplexing, HD FDD, operation; performing downlink assignments for the network node according to the fixed periodic pattern; and transmitting uplink grants to the UE according to the fixed periodic pattern, wherein the UE is a Type A UE, and the at least one guard period comprises a guard time within a downlink subframe, or wherein the user equipment is a Type B UE, and the at least one guard period comprises a guard subframe between a downlink subframe and a uplink subframe, wherein the Type A UE is a Type A HD FDD UE having the guard time created by the UE by not receiving a last part of the downlink subframe immediately preceding the uplink subframe from the same UE, and wherein the Type B UE is a Type B HD FDD UE having the guard subframe by not receiving the downlink subframe immediately preceding or following the uplink subframe; characterized in transmitting uplink grants to a Type B HD FDD UE according to the fixed periodic pattern, wherein the fixed periodic pattern defines a sequence of twelve consecutive subframes, including a downlink subframe followed by a guard subframe, then six uplink subframes, then two guard subframes, and then two downlink subframes. identifying a fixed periodic pattern to be used for scheduling a half-duplex, HD, user equipment, UE, the fixed periodic pattern defining a sequence of at least one downlink subframe, then at least one guard period, and then at least one uplink subframe, wherein the UE is configured for HD frequency division duplexing, HD FDD, operation; performing downlink assignments for the network node according to the fixed periodic pattern; and transmitting uplink grants to the UE according to the fixed periodic pattern, wherein the UE is a Type A UE, and the at least one guard period comprises a guard time within a downlink subframe, or wherein the user equipment is a Type B UE, and the at least one guard period comprises a guard subframe between a downlink subframe and a uplink subframe, wherein the Type A UE is a Type A HD FDD UE having the guard time created by the UE by not receiving a last part of the downlink subframe immediately preceding the uplink subframe from the same UE, and wherein the Type B UE is a Type B HD FDD UE having the guard subframe by not receiving the downlink subframe immediately preceding or following the uplink subframe; characterized in transmitting uplink grants to a Type B HD FDD UE according to the fixed periodic pattern, wherein the fixed periodic pattern defines a sequence of twelve consecutive subframes, including a downlink subframe followed by a guard subframe, then six uplink subframes, then two guard subframes, and then two downlink subframes.
An apparatus for generating sputtering of a target to produce a coating on a substrate comprising: a magnetron including a cathode and an anode; a power supply operably connected to the magnetron; at least one capacitor operably connected to the power supply; an inductance operably connected to the at least one capacitor; a first switch (S 1) operably connecting the power supply to the magnetron to charge the magnetron and configured for administering a first pulse to the magnetron; characterized by a second switch (S 2) operably connected to discharge the magnetron and configured to discharge the magnetron according to a second pulse. a magnetron including a cathode and an anode; a power supply operably connected to the magnetron; at least one capacitor operably connected to the power supply; an inductance operably connected to the at least one capacitor; a first switch (S 1) operably connecting the power supply to the magnetron to charge the magnetron and configured for administering a first pulse to the magnetron; characterized by a second switch (S 2) operably connected to discharge the magnetron and configured to discharge the magnetron according to a second pulse.
A pharmaceutical product comprising: a container comprising a receptacle having a wall including a layer of nickel or nickel alloy, the layer facing an interior of the receptacle; and a halogenated anesthetic selected from the group consisting of sevoflurane, desflurane, isoflurane, enflurane, methoxyflurane and halothane disposed within the container. a container comprising a receptacle having a wall including a layer of nickel or nickel alloy, the layer facing an interior of the receptacle; and a halogenated anesthetic selected from the group consisting of sevoflurane, desflurane, isoflurane, enflurane, methoxyflurane and halothane disposed within the container.
A primer composition for an optical article comprising; aqueous dispersion of urethane resin having a polycarbonate-derived skeleton (A-component); polyester resin (B-component); inorganic oxide fine particles (C-component); and water (D-component), characterized in that to 100 parts by weight of A-component, B-component is 10∼95 parts by weight, C-component is 70∼300 parts by weight, and D-component is 150∼2300 parts by weight. aqueous dispersion of urethane resin having a polycarbonate-derived skeleton (A-component); polyester resin (B-component); inorganic oxide fine particles (C-component); and water (D-component), characterized in that to 100 parts by weight of A-component, B-component is 10∼95 parts by weight, C-component is 70∼300 parts by weight, and D-component is 150∼2300 parts by weight.
Retaining element for an installation housing, the retaining element being designed as an elongated plastic component, the retaining element having a sleeve section in its front region and an extension section in its rear region which is integrally connected to the sleeve section, the sleeve section forming a screw receptacle, wherein the sleeve section is closed at its one end and has a closable opening at its opposite end, and wherein a guide element extending in the longitudinal direction of the retaining element is arranged on a longitudinal side of the retaining element for fastening the retaining element to the installation housing, characterized in in that the sleeve section has a closure (21.1) and, at its end facing the extension section, is designed to be closable with the closure (21.1) opposite the closed end.
A seat cushion for supporting at least a portion of a user relative to a support surface, the cushion comprising: material with sufficient flexibility for the cushion to deform from an unloaded configuration toward a loaded configuration as a weight of the user is placed on the cushion, and with sufficient resilience for the cushion to return toward an unloaded configuration as the weight of the user is removed from the cushion, and with sufficient stiffness that the cushion deforms predominantly by bending as a load is applied; a body; a sitting face on a top side of the body, the sitting face configured to contact portions of the body of the user when supported by the cushion and comprising a contour configured to match a generic anatomical shape of a seated user and configured to aid in positioning the seated user in a therapeutically optimum position, and; a supporting face on an under side of the body and characterized by a plurality of points, the supporting face contoured such that when the cushion is in the unloaded configuration a first subset of the plurality of points contact the support surface and a second subset of the plurality of points do not contact the support surface, and when the cushion is in the loaded configuration at least some of the points in the second subset contact the support surface, the second subset of the plurality of points further being positioned below the contour of the sitting face, such that pelvic retrusion of the seated user is mitigated. material with sufficient flexibility for the cushion to deform from an unloaded configuration toward a loaded configuration as a weight of the user is placed on the cushion, and with sufficient resilience for the cushion to return toward an unloaded configuration as the weight of the user is removed from the cushion, and with sufficient stiffness that the cushion deforms predominantly by bending as a load is applied; a body; a sitting face on a top side of the body, the sitting face configured to contact portions of the body of the user when supported by the cushion and comprising a contour configured to match a generic anatomical shape of a seated user and configured to aid in positioning the seated user in a therapeutically optimum position, and; a supporting face on an under side of the body and characterized by a plurality of points, the supporting face contoured such that when the cushion is in the unloaded configuration a first subset of the plurality of points contact the support surface and a second subset of the plurality of points do not contact the support surface, and when the cushion is in the loaded configuration at least some of the points in the second subset contact the support surface, the second subset of the plurality of points further being positioned below the contour of the sitting face, such that pelvic retrusion of the seated user is mitigated.
A non-transitory computer-readable storage medium having computer-executable instructions for causing a computing system to perform a method of generating a radiation treatment plan, the method comprising: accessing values of parameters from memory of the computing system, wherein the parameters comprise directions of beams to be directed into sub-volumes in a target and beam energies for the beams; accessing information that specifies limits for the radiation treatment plan, wherein the limits comprise a maximum limit on irradiation time for each sub-volume outside the target; and adjusting the values of the parameters until the irradiation time for said each sub-volume outside the target satisfies the maximum limit on irradiation time. accessing values of parameters from memory of the computing system, wherein the parameters comprise directions of beams to be directed into sub-volumes in a target and beam energies for the beams; accessing information that specifies limits for the radiation treatment plan, wherein the limits comprise a maximum limit on irradiation time for each sub-volume outside the target; and adjusting the values of the parameters until the irradiation time for said each sub-volume outside the target satisfies the maximum limit on irradiation time.
A powered air cleaning system comprising: a generally cylindrical housing having a central longitudinal axis (A-A) and an inlet and an outlet at respective axial ends of the housing; a flow path extending through the system from an inlet to an outlet; a motor-driven fan located along the flow path to draw particulate debris laden air into the inlet and rotate it about the axis to form a rotating flow that stratifies the debris laden air with the heaviest particles in the outermost orbits of the rotating flow; an ejector port for ejecting particulate debris laden air from the stratified rotating flow in the system; and an air filter located within the housing and across the flow path upstream of the outlet for filtering air from the innermost orbits of the stratified rotating flow, the air filter being elongated in the direction of the axis; characterized in that the ejector port is arranged in the generally cylindrical outer wall of the housing radially outward from the air filter and is in the form of an ejector slot which extends the length of the air filter. a generally cylindrical housing having a central longitudinal axis (A-A) and an inlet and an outlet at respective axial ends of the housing; a flow path extending through the system from an inlet to an outlet; a motor-driven fan located along the flow path to draw particulate debris laden air into the inlet and rotate it about the axis to form a rotating flow that stratifies the debris laden air with the heaviest particles in the outermost orbits of the rotating flow; an ejector port for ejecting particulate debris laden air from the stratified rotating flow in the system; and an air filter located within the housing and across the flow path upstream of the outlet for filtering air from the innermost orbits of the stratified rotating flow, the air filter being elongated in the direction of the axis; characterized in that the ejector port is arranged in the generally cylindrical outer wall of the housing radially outward from the air filter and is in the form of an ejector slot which extends the length of the air filter.
A radio frequency identification, RFID, system comprising: a storage medium comprising a plurality of stored waveforms, each stored waveform representing an RFID symbol usable in a sequence of RFID symbols; and a polarity generator to selectively impart a required polarity to each stored waveform to assemble the sequence of RFID symbols, wherein each stored waveform has been produced by a processor configured to: assemble a prototype waveform using sinusoidal rising and falling edges for each symbol from among the plurality of RFID symbols; create lower and upper bounds for the prototype waveform so that rise and fall times are preserved; construct a periodic waveform from the prototype waveform; and execute an optimization algorithm using the periodic waveform to extract a run time waveform, wherein the optimization algorithm minimizes spectral occupancy. a storage medium comprising a plurality of stored waveforms, each stored waveform representing an RFID symbol usable in a sequence of RFID symbols; and a polarity generator to selectively impart a required polarity to each stored waveform to assemble the sequence of RFID symbols, wherein each stored waveform has been produced by a processor configured to: assemble a prototype waveform using sinusoidal rising and falling edges for each symbol from among the plurality of RFID symbols; create lower and upper bounds for the prototype waveform so that rise and fall times are preserved; construct a periodic waveform from the prototype waveform; and execute an optimization algorithm using the periodic waveform to extract a run time waveform, wherein the optimization algorithm minimizes spectral occupancy. assemble a prototype waveform using sinusoidal rising and falling edges for each symbol from among the plurality of RFID symbols; create lower and upper bounds for the prototype waveform so that rise and fall times are preserved; construct a periodic waveform from the prototype waveform; and execute an optimization algorithm using the periodic waveform to extract a run time waveform, wherein the optimization algorithm minimizes spectral occupancy.
A dissolvable article in the form of a porous dissolvable solid structure, comprising: a. from 10% to 50% water soluble polymer; b. from 1% to 25% plasticizer; c. from 23% to 75% surfactant; wherein said surfactants comprise: i. one or more surfactants from Group I, wherein Group I surfactant is selected from anionic surfactants, and ii. one or more surfactants from Group II, wherein Group II surfactant is selected from the group consisting of amphoteric, zwitterionic and combinations thereof; wherein the ratio of Group I to Group II surfactants is from 70:30 to 55:45; and wherein said Group II surfactant comprises an amphoteric surfactant according to the following structure: wherein R 1 is a C-linked monovalent substituent selected from the group consisting of substituted alkyl systems comprising 9 to 15 carbon atoms, unsubstituted alkyl systems comprising 9 to 15 carbon atoms, straight alkyl systems comprising 9 to 15 carbon atoms, branched alkyl systems comprising 9 to 15 carbon atoms, and unsaturated alkyl systems comprising 9 to 15 carbon atoms; R 2, R 3, and R 4 are each independently selected from the group consisting of C-linked divalent straight alkyl systems comprising 1 to 3 carbon atoms, and C-linked divalent branched alkyl systems comprising 1 to 3 carbon atoms; and M + is a monovalent counterion selected from the group consisting of sodium, ammonium and protonated triethanolamine; and wherein said dissolvable article has a density of from 0.05 g/cm3 to 0.25 g/cm3, as calculated according to the density calculation method. a. from 10% to 50% water soluble polymer; b. from 1% to 25% plasticizer; c. from 23% to 75% surfactant; wherein said surfactants comprise: i. one or more surfactants from Group I, wherein Group I surfactant is selected from anionic surfactants, and ii. one or more surfactants from Group II, wherein Group II surfactant is selected from the group consisting of amphoteric, zwitterionic and combinations thereof; i. one or more surfactants from Group I, wherein Group I surfactant is selected from anionic surfactants, and ii. one or more surfactants from Group II, wherein Group II surfactant is selected from the group consisting of amphoteric, zwitterionic and combinations thereof;