mhurhangee/ep-ind-claims huggingface dataset:
A transformant transformed with a recombinant vector comprising a DNA construct comprising: a 5'-untranslated region of an alcohol dehydrogenase gene derived from Nicotiana tabacum; and a DNA encoding a B subunit of the Stx2e protein added with a secretory signal peptide derived from Nicotiana tabacum at an amino terminus and operably-linked to the region, wherein the B subunit of the Stx2e protein includes an endoplasmic reticulum retention signal peptide or a vacuolar transport signal peptide added at a carboxyl terminus, wherein the endoplasmic reticulum retention signal peptide includes a HDEL sequence at the carboxyl terminus. a 5'-untranslated region of an alcohol dehydrogenase gene derived from Nicotiana tabacum; and a DNA encoding a B subunit of the Stx2e protein added with a secretory signal peptide derived from Nicotiana tabacum at an amino terminus and operably-linked to the region, wherein the B subunit of the Stx2e protein includes an endoplasmic reticulum retention signal peptide or a vacuolar transport signal peptide added at a carboxyl terminus, wherein the endoplasmic reticulum retention signal peptide includes a HDEL sequence at the carboxyl terminus.
A system, comprising: a transmitter to generate a power beam; a receiver to receive at least a portion of the power beam; a plurality of sensors arranged to independently detect when an object (122, 124) is impinging on the power beam, at least a first set of one or more sensors of the plurality of sensors arranged to detect the object at or within a first detection volume between the transmitter and the receiver, at least a second set of one or more sensors of the plurality of sensors arranged to detect the object at or within a second detection volume between the transmitter and the receiver, the first detection volume including a first distance range from the transmitter and the second detection volume including a second distance range from the transmitter, the first distance range being different from the second distance range; and a controller to interrupt transmission of the power beam to the receiver when, based on information from one or more of the plurality of sensors, the object is determined to be impinging on the power beam. a transmitter to generate a power beam; a receiver to receive at least a portion of the power beam; a plurality of sensors arranged to independently detect when an object (122, 124) is impinging on the power beam, at least a first set of one or more sensors of the plurality of sensors arranged to detect the object at or within a first detection volume between the transmitter and the receiver, at least a second set of one or more sensors of the plurality of sensors arranged to detect the object at or within a second detection volume between the transmitter and the receiver, the first detection volume including a first distance range from the transmitter and the second detection volume including a second distance range from the transmitter, the first distance range being different from the second distance range; and a controller to interrupt transmission of the power beam to the receiver when, based on information from one or more of the plurality of sensors, the object is determined to be impinging on the power beam.
A compound of formula wherein: A is 5- or 6-membered heteroaryl ring comprising at least one nitrogen atom, wherein the 5- or 6-membered heteroaryl ring is optionally substituted with one substituent selected from the group consisting of C 1-3 -alkyl, C 1-3 -alkoxy and halo; R 1 is hydrogen, C 1-3 -alkoxy, C 1-3 -alkyl, cyano or halo; R 2 is C 1-6 -alkyl optionally substituted with one or more substituents independently selected from the group consisting of hydroxy, halo and cyano, or C 3-7 -cycloalkyl-C 1-3 -alkyl, heterocyclyl-C 1-3 -alkyl or phenyl-C 1-3 -alkyl, wherein any C 3-7 -cycloalkyl, heterocyclyl and phenyl rings are optionally substituted with one or more substituents independently selected from the group consisting of fluoro and C 1-3 -alkyl; R 3, R 5 and R 7 are each independently selected from the group consisting of hydrogen, C 1-3 -alkyl, C 3-7 -cycloalkyl and phenyl, wherein C 1-3 -alkyl, C 3-7 -cycloalkyl and phenyl are optionally substituted with one or more substituents independently selected from the group consisting of fluoro and C 1-3 -alkyl; R 4, R 6 and R 8 are each independently hydrogen, fluoro, C 1-3 -alkyl or fluoro-C 1-3 -alkyl; or R 3 and R 4, or R 5 and R 6, or R 7 and R 8, together with the carbon atom to which they are attached, form a 3- to 7-membered saturated ring, which optionally contains an oxygen or nitrogen atom, and which ring is optionally substituted with one or more substituents independently selected from the group consisting of fluoro and C 1-3 -alkyl; as a free base or a pharmaceutically acceptable salt thereof. A is 5- or 6-membered heteroaryl ring comprising at least one nitrogen atom, wherein the 5- or 6-membered heteroaryl ring is optionally substituted with one substituent selected from the group consisting of C 1-3 -alkyl, C 1-3 -alkoxy and halo; R 1 is hydrogen, C 1-3 -alkoxy, C 1-3 -alkyl, cyano or halo; R 2 is C 1-6 -alkyl optionally substituted with one or more substituents independently selected from the group consisting of hydroxy, halo and cyano, or C 3-7 -cycloalkyl-C 1-3 -alkyl, heterocyclyl-C 1-3 -alkyl or phenyl-C 1-3 -alkyl, wherein any C 3-7 -cycloalkyl, heterocyclyl and phenyl rings are optionally substituted with one or more substituents independently selected from the group consisting of fluoro and C 1-3 -alkyl; R 3, R 5 and R 7 are each independently selected from the group consisting of hydrogen, C 1-3 -alkyl, C 3-7 -cycloalkyl and phenyl, wherein C 1-3 -alkyl, C 3-7 -cycloalkyl and phenyl are optionally substituted with one or more substituents independently selected from the group consisting of fluoro and C 1-3 -alkyl; R 4, R 6 and R 8 are each independently hydrogen, fluoro, C 1-3 -alkyl or fluoro-C 1-3 -alkyl; or R 3 and R 4, or R 5 and R 6, or R 7 and R 8, together with the carbon atom to which they are attached, form a 3- to 7-membered saturated ring, which optionally contains an oxygen or nitrogen atom, and which ring is optionally substituted with one or more substituents independently selected from the group consisting of fluoro and C 1-3 -alkyl; as a free base or a pharmaceutically acceptable salt thereof.
A structural element for the decoupling of impact sound for stair flights, with an insulating bearing layer that can be inserted between a stair flight and a floor supporting the latter, or a landing supporting the latter, wherein the insulating bearing layer comprises a foamed material layer with an upper face and a lower face, in which a first elastomer is embedded; on at least one of the two faces (10A, 10B) in the region of the first elastomer at least one layer of a second elastomer is provided, wherein this layer is designed to be thinner than the first elastomer, characterised in that, the first elastomer and the second elastomer have different Shore A hardnesses, wherein the first elastomer has a higher Shore A hardness than the second elastomer.
An exenatide analog having 7 to 9 amino acid deletions in the C-terminal of the amino acid sequence of exenatide and comprising a fatty acid conjugated thereto, wherein the amino acid sequence of the exenatide is SEQ ID NO: 1, and the fatty acid is conjugated to the C-terminal of the amino acid-deleted exenatide via a lysine linker.
A bottle comprising: - a flexible main part with an inner part for receiving a liquid therein, wherein the main part includes an upper part and a lower part; - an opening part located in the upper part of the main part, which is intended for receiving of the liquid in the inner part of the main part and for discharging the liquid from the inner part of the main part; - a closure part above the opening part to restrict the receiving and discharging of the liquid; characterized in that a strap is embedded in the main part such that the upper part, along with the opening part and the closure part, can be bent and secured behind the strap; or a pocket is embedded in the main part such that the upper part, along with the opening part and the closure part, can be bent and hidden in the pocket. - a flexible main part with an inner part for receiving a liquid therein, wherein the main part includes an upper part and a lower part; - an opening part located in the upper part of the main part, which is intended for receiving of the liquid in the inner part of the main part and for discharging the liquid from the inner part of the main part; - a closure part above the opening part to restrict the receiving and discharging of the liquid; characterized in that a strap is embedded in the main part such that the upper part, along with the opening part and the closure part, can be bent and secured behind the strap; or a pocket is embedded in the main part such that the upper part, along with the opening part and the closure part, can be bent and hidden in the pocket.
A data switching system, comprising K subsystems, wherein a first subsystem in the K subsystems comprises M switching apparatuses, a first switching apparatus in the M switching apparatuses comprises X network side ports, and the X network side ports comprise M-1 intra-group ports and K-1 inter-group ports, wherein the M-1 intra-group ports are respectively connected to M-1 switching apparatuses in the first subsystem except the first switching apparatus; and the K-1 inter-group ports are respectively connected to direct switching apparatuses, of the first switching apparatus, in K-1 subsystems in the K subsystems except the first subsystem; the first subsystem is any one of the K subsystems and the first switching apparatus is any one of the M switching apparatuses, K≥2 and M≥2; characterized in that the first subsystem further comprises an N ∗ N intra-group optical interleaver; each network side port comprises a transmit optical interface and a receive optical interface; and that the M-1 intra-group ports are respectively connected to M-1 switching apparatuses in the first subsystem except the first switching apparatus comprises: all transmit optical interfaces of the M-1 intra-group ports are connected to an input port of the N ∗ N intra-group optical interleaver, and all receive optical interfaces of the M-1 intra-group ports are connected to an output port of the N ∗ N intra-group optical interleaver, so as to connect to the M-1 switching apparatuses in the first subsystem except the first switching apparatus by using the N ∗ N intra-group optical interleaver, wherein M and N are both natural numbers, and M≤N. all transmit optical interfaces of the M-1 intra-group ports are connected to an input port of the N ∗ N intra-group optical interleaver, and all receive optical interfaces of the M-1 intra-group ports are connected to an output port of the N ∗ N intra-group optical interleaver, so as to connect to the M-1 switching apparatuses in the first subsystem except the first switching apparatus by using the N ∗ N intra-group optical interleaver, wherein M and N are both natural numbers, and M≤N.
Device for laterally guiding a rolled or cast product in the form of a metal strip, a slab or the like on a transport track, comprising a first guide and a second guide, wherein the guides (4, 5) are arranged opposite one another on either side of the transport track and are each connected, for movement in the direction of the width of the transport track, with at least one setting drive actuable perpendicularly to the transport direction of the rolled or cast product, wherein the first guide and/or the second guide can be so positioned by actuation of the respectively associated setting drive that they can be positioned independently of one another with the respective longitudinal axes (4 L, 5 L) thereof at a predetermined angle (α) relative to the transport direction of the rolled or cast product and/or at a different spacing from the transport track centre (3 M), and wherein the first guide and/or the second guide has or have at least one contact roller which can be brought into contact with a lateral edge of the rolled or cast product by movement of the corresponding guide (4, 5) in order to guide the rolled or cast product and/or to reduce the width thereof by upsetting, characterised in that the first and/or the second guide (4, 5) has or have two respective contact rollers respectively mounted at the inlet-side end and the outlet-side end of the corresponding guide (4, 5).
An iron-type golf club head comprising: a body having a wall extending about an opening, the wall having an outer peripheral surface, a first hardness value, a sole, a toe and a topline; a faceplate coupled to the body across the opening, the wall and the faceplate defining a rearward-facing cavity; a plurality of apertures extending through the wall from the peripheral outer surface to the cavity, the plurality of apertures comprising at least five apertures, and wherein at least one of the plurality of apertures extends through the sole of the wall; and a plurality of plugs with a separate one of the plurality of plugs positioned within a separate one of the plurality of apertures, the plurality of plugs comprising at least five plugs, and the plurality of plugs each having a hardness value, each of the plug hardness values being less than the first hardness value. a body having a wall extending about an opening, the wall having an outer peripheral surface, a first hardness value, a sole, a toe and a topline; a faceplate coupled to the body across the opening, the wall and the faceplate defining a rearward-facing cavity; a plurality of apertures extending through the wall from the peripheral outer surface to the cavity, the plurality of apertures comprising at least five apertures, and wherein at least one of the plurality of apertures extends through the sole of the wall; and a plurality of plugs with a separate one of the plurality of plugs positioned within a separate one of the plurality of apertures, the plurality of plugs comprising at least five plugs, and the plurality of plugs each having a hardness value, each of the plug hardness values being less than the first hardness value.
Apparatus for determining the position of an object that is movable in at least one displacement direction, wherein the, or each, displacement direction is associated with a length measuring device for measuring the position of the object along the respective displacement direction, which length measuring device has, as a first component, a graduated scale (20, 30) which extends along the associated displacement direction (x, y), having a sensing head (25, 35) for sensing the graduated scale (20, 30) as a second component of the respective length measuring device (2, 3), such that a change in the position of the graduated scale (20, 30) is measurable with respect to the sensing head (25, 35) along the associated displacement direction (x, y), wherein during a movement of the object to be measured, one of the two components (20, 25; 30, 35) of the respective length measurement device (2, 3) is moved together with said object along the respective displacement direction (x, y), and characterized in that the apparatus furthermore has a device (12, 23; 13, 33) for determining the distance of that component (20, 30) of the respective length measuring device (2, 3) which is movable together with the object to be measured from the object to be measured along the extent direction (x, y) of the graduated scale (20, 30) of the length measuring device (2, 3), wherein the device (12, 23; 13, 33) for determining the distance of that component (20, 30) of the respective length measurement device (2, 3) which is movable together with the object to be measured from the object to be measured comprises a measurement graduation (12, 13) as a first structural element and an associated measuring head (23, 33) as a second structural element, wherein one of the two structural elements (12, 23; 13, 33) is provided at the object to be measured and the other one of the two structural elements (12, 23; 13, 33) is provided at that component (20, 30) of the length measuring device (2, 3) which is movable together with the object to be measured.
A method of repairing a slip joint on a jet pump assembly between an inlet mixer and a diffuser, the diffuser having a diffuser collar and an opening that receives the inlet mixer with a given spacing between an outside diameter of the inlet mixer and an inside diameter of the opening in the diffuser forming an annular gap, characterized by inserting a new internal collar into the diffuser collar between the diffuser and the inlet mixer narrowing the annular gap between the inlet mixer and the diffuser collar with the new internal collar structured to form an axially convergent geometry relative to the outside diameter of the inlet mixer.
A device, comprising: a elongate stimulating assembly of an implantable stimulating device, including a lead assembly made at least partially of material having elasticity and a proximal region and an intra-cochlear region forming an electrode array. characterized by a first structure (610, 710, 910) including a first malleable component and co-located with the lead assembly, wherein the first structure is configured to deform upon the application of sufficient force, which force is greater than a force applied to the structure via the elasticity, thereby moving the lead assembly along with the deformation, so that the device resists movement of at least a portion of the lead assembly, the movement of the lead assembly due to the elasticity, wherein the first structure extends partially or fully along the length of the lead assembly up to the electrode array. a elongate stimulating assembly of an implantable stimulating device, including a lead assembly made at least partially of material having elasticity and a proximal region and an intra-cochlear region forming an electrode array. characterized by a first structure (610, 710, 910) including a first malleable component and co-located with the lead assembly, wherein the first structure is configured to deform upon the application of sufficient force, which force is greater than a force applied to the structure via the elasticity, thereby moving the lead assembly along with the deformation, so that the device resists movement of at least a portion of the lead assembly, the movement of the lead assembly due to the elasticity, wherein the first structure extends partially or fully along the length of the lead assembly up to the electrode array.
A method of manufacturing the absorbent article claimed in claim 11, the method comprising: feeding a first web of material in a machine direction; feeding a second web of material in the machine direction, the second web being spaced from the first web by a gap; attaching an absorbent assembly to the first web and the second web such that the absorbent assembly spans the gap between the first and second webs; forming a partial cut line through the second web; folding the first web into face-to-face relationship with the second web after forming the partial cut line; and cutting the first and second webs after folding the first web into face-to-face relationship with the second web to separate the absorbent article from the first and second webs, the partial cut line defining at least one finger tab on the absorbent article. feeding a first web of material in a machine direction; feeding a second web of material in the machine direction, the second web being spaced from the first web by a gap; attaching an absorbent assembly to the first web and the second web such that the absorbent assembly spans the gap between the first and second webs; forming a partial cut line through the second web; folding the first web into face-to-face relationship with the second web after forming the partial cut line; and cutting the first and second webs after folding the first web into face-to-face relationship with the second web to separate the absorbent article from the first and second webs, the partial cut line defining at least one finger tab on the absorbent article.
An indoor unit of an air-conditioning apparatus, the indoor unit having a body placed on a wall surface of a room that is an air-conditioned space, the indoor unit comprising a temperature sensor disposed at a position projecting from the body, and including a temperature detector configured to detect a temperature based on heat radiation from a target and a driver configured to cause the temperature detector to rotate, characterized in that the temperature sensor is disposed at the position being a place where the temperature sensor is capable of detecting a temperature in all the horizontal directions by rotating the temperature detector, wherein the indoor unit further comprises a controller configured to determine, as being the target, a wall on which the body is placed based on the temperature detected by the temperature sensor, and wherein the controller derives a sensible temperature in the room based on the temperature at the location determined as the wall on which the body is placed. a temperature sensor disposed at a position projecting from the body, and including a temperature detector configured to detect a temperature based on heat radiation from a target and a driver configured to cause the temperature detector to rotate, characterized in that the temperature sensor is disposed at the position being a place where the temperature sensor is capable of detecting a temperature in all the horizontal directions by rotating the temperature detector, wherein the indoor unit further comprises a controller configured to determine, as being the target, a wall on which the body is placed based on the temperature detected by the temperature sensor, and wherein the controller derives a sensible temperature in the room based on the temperature at the location determined as the wall on which the body is placed.
A conductive composition which comprises silver fine particles having a number average particle diameter of primary particles of 40 nm to 400 nm, a solvent and thermoplastic resin particles having a maximal value of an endothermic peak in a DSC chart obtained by a measurement using a differential scanning calorimeter within the range of 80°C to 170°C, wherein the number average particle diameter of primary particles of the thermoplastic resin particles is 1 to 50 μm.
A positive electrode plate, comprising a current collector, a positive active material layer and a safety coating disposed between the current collector and the positive active material layer, the safety coating comprising a polymer matrix, a conductive material and an inorganic filler, wherein the polymer matrix is fluorinated polyolefin and/or chlorinated polyolefin; wherein based on the total weight of the safety coating, a weight percentage of the polymer matrix is from 35 wt% to 75 wt%, a weight percentage of the conductive material is from 5 wt% to 25 wt%, and a weight percentage of the inorganic filler is from 10 wt% to 60 wt%; and wherein the inorganic filler is a carbon coating modified positive electrochemically active material. wherein the polymer matrix is fluorinated polyolefin and/or chlorinated polyolefin; wherein based on the total weight of the safety coating, a weight percentage of the polymer matrix is from 35 wt% to 75 wt%, a weight percentage of the conductive material is from 5 wt% to 25 wt%, and a weight percentage of the inorganic filler is from 10 wt% to 60 wt%; and wherein the inorganic filler is a carbon coating modified positive electrochemically active material.