A system for treating glaucoma in an eye comprising a cornea, an anterior chamber, a Schlemm's canal, and a trabecular meshwork therebetween, the system comprising: a first optical subsystem including a focusing objective configured to be coupled to the cornea; a second optical subsystem including: a laser source configured to output a laser beam, and a plurality of components configured to one or more of condition, scan, and direct the laser beam through the focusing objective; and a control system coupled to the second optical subsystem and configured to: design an initial treatment pattern that defines an initial volume of ocular tissue to be modified; instruct the laser source to deliver an initial laser treatment by scanning a laser beam across ocular tissue at an initial placement in the eye in accordance with the initial treatment pattern to thereby photo disrupt the initial volume of ocular tissue; evaluate a postoperative measure of the intraocular pressure, IOP, relative to an IOP criterion; and if the IOP criterion is not satisfied: determine a subsequent treatment pattern that defines a subsequent volume of ocular tissue to be modified, and a subsequent placement in the eye, instruct the laser source to deliver a subsequent laser treatment by scanning a laser beam across ocular tissue at the subsequent placement within the eye in accordance with the subsequent treatment pattern to thereby photo disrupt the subsequent volume of ocular tissue, and repeat the evaluating. a first optical subsystem including a focusing objective configured to be coupled to the cornea; a second optical subsystem including: a laser source configured to output a laser beam, and a plurality of components configured to one or more of condition, scan, and direct the laser beam through the focusing objective; and a control system coupled to the second optical subsystem and configured to: design an initial treatment pattern that defines an initial volume of ocular tissue to be modified; instruct the laser source to deliver an initial laser treatment by scanning a laser beam across ocular tissue at an initial placement in the eye in accordance with the initial treatment pattern to thereby photo disrupt the initial volume of ocular tissue; evaluate a postoperative measure of the intraocular pressure, IOP, relative to an IOP criterion; and if the IOP criterion is not satisfied: determine a subsequent treatment pattern that defines a subsequent volume of ocular tissue to be modified, and a subsequent placement in the eye, instruct the laser source to deliver a subsequent laser treatment by scanning a laser beam across ocular tissue at the subsequent placement within the eye in accordance with the subsequent treatment pattern to thereby photo disrupt the subsequent volume of ocular tissue, and repeat the evaluating. design an initial treatment pattern that defines an initial volume of ocular tissue to be modified; instruct the laser source to deliver an initial laser treatment by scanning a laser beam across ocular tissue at an initial placement in the eye in accordance with the initial treatment pattern to thereby photo disrupt the initial volume of ocular tissue; evaluate a postoperative measure of the intraocular pressure, IOP, relative to an IOP criterion; and if the IOP criterion is not satisfied: determine a subsequent treatment pattern that defines a subsequent volume of ocular tissue to be modified, and a subsequent placement in the eye, instruct the laser source to deliver a subsequent laser treatment by scanning a laser beam across ocular tissue at the subsequent placement within the eye in accordance with the subsequent treatment pattern to thereby photo disrupt the subsequent volume of ocular tissue, and repeat the evaluating. determine a subsequent treatment pattern that defines a subsequent volume of ocular tissue to be modified, and a subsequent placement in the eye, instruct the laser source to deliver a subsequent laser treatment by scanning a laser beam across ocular tissue at the subsequent placement within the eye in accordance with the subsequent treatment pattern to thereby photo disrupt the subsequent volume of ocular tissue, and repeat the evaluating.