mhurhangee/ep-ind-claims huggingface dataset:
A computer implemented method for permitting manipulation of an achievable dose distribution estimate deliverable by a radiation delivery apparatus for proposed treatment of a subject, the achievable dose distribution estimate defined over a three-dimensional range of voxels with a dose value for each voxel, the method comprising: (a) determining a dose modification voxel for which it is desired to modify the dose value and determining a corresponding magnitude of desired dose modification; (b) for each of a plurality of beams: (i) characterizing the beam as a two-dimensional array of beamlets, wherein each beamlet is associated with a corresponding intensity value and a ray line representing a projection of the beamlet into space; and (ii) identifying one or more dose-change beamlets which have associated ray lines that intersect the dose modification voxel; (c) modifying the intensity values of the identified dose-change beamlets based on the magnitude of desired dose modification, wherein modifying the intensity value of the identified dose-change beamlets comprises, for each of the identified dose-change beamlets, modifying the intensity value of the identified dose-change beamlet according to a function that is proportional to the magnitude of desired dose modification and inversely proportional to the number of the identified dose-change beamlets; and (d) updating the achievable dose distribution estimate based on the modified intensity values of the identified dose-change beamlets. (a) determining a dose modification voxel for which it is desired to modify the dose value and determining a corresponding magnitude of desired dose modification; (b) for each of a plurality of beams: (i) characterizing the beam as a two-dimensional array of beamlets, wherein each beamlet is associated with a corresponding intensity value and a ray line representing a projection of the beamlet into space; and (ii) identifying one or more dose-change beamlets which have associated ray lines that intersect the dose modification voxel; (i) characterizing the beam as a two-dimensional array of beamlets, wherein each beamlet is associated with a corresponding intensity value and a ray line representing a projection of the beamlet into space; and (ii) identifying one or more dose-change beamlets which have associated ray lines that intersect the dose modification voxel; (c) modifying the intensity values of the identified dose-change beamlets based on the magnitude of desired dose modification, wherein modifying the intensity value of the identified dose-change beamlets comprises, for each of the identified dose-change beamlets, modifying the intensity value of the identified dose-change beamlet according to a function that is proportional to the magnitude of desired dose modification and inversely proportional to the number of the identified dose-change beamlets; and (d) updating the achievable dose distribution estimate based on the modified intensity values of the identified dose-change beamlets.
An array substrate, comprising: a plurality of gate lines and a plurality of data lines configured to intersect with each other; and sub-pixel units formed by the intersection of the gate lines and the data lines, the sub-pixels units forming a pixel region, wherein each sub-pixel unit comprises: a first transparent common electrode; a pixel electrode disposed above and insulated from the first transparent common electrode; and a second transparent common electrode disposed above and insulated from the pixel electrode, characterized in that the array substrate further comprises an electrically conductive structure that covers and is in direct contact with an end of the gate line or an end of the data line outside the pixel region of the array substrate, and that is disposed in a same layer as the first transparent common electrode, the orthographic projection of the first transparent common electrode on the plane having the pixel electrode is located within a region of the pixel electrode, and the first transparent common electrode has a hollow portion, and the orthographic projection of the hollow portion on the plane having the pixel electrode is located in the region of the pixel electrode. a plurality of gate lines and a plurality of data lines configured to intersect with each other; and sub-pixel units formed by the intersection of the gate lines and the data lines, the sub-pixels units forming a pixel region, wherein each sub-pixel unit comprises: a first transparent common electrode; a pixel electrode disposed above and insulated from the first transparent common electrode; and a second transparent common electrode disposed above and insulated from the pixel electrode, a first transparent common electrode; a pixel electrode disposed above and insulated from the first transparent common electrode; and a second transparent common electrode disposed above and insulated from the pixel electrode, characterized in that the array substrate further comprises an electrically conductive structure that covers and is in direct contact with an end of the gate line or an end of the data line outside the pixel region of the array substrate, and that is disposed in a same layer as the first transparent common electrode, the orthographic projection of the first transparent common electrode on the plane having the pixel electrode is located within a region of the pixel electrode, and the first transparent common electrode has a hollow portion, and the orthographic projection of the hollow portion on the plane having the pixel electrode is located in the region of the pixel electrode.
Construction machine (1, 1') for the processing and/or transport of material (9, 9') having a temperature-dependent viscosity, the construction machine (1, 1') being a road finisher or a feeder, comprising: a machine frame (2, 2') on which a material bunker (3, 3'), an operator's platform (4, 4'), a primary drive (5, 5') as well as an undercarriage (6, 6') with propulsion elements (7, 7') are provided, at least one conveyor system (10, 10') which is configured to convey the material, wherein the conveyor system (10, 10') comprises at least one screw conveyor (11, 11'), and the at least one screw conveyor (11, 11') is supported by at least one bearing structure (12, 12'), characterized in that the bearing structure (12, 12') can be heated by at least one heating element (14, 14', 14") which is arranged in a hollow space (18, 18') present inside the bearing structure (12, 12') or provided on an outside of the bearing structure (12, 12'). a machine frame (2, 2') on which a material bunker (3, 3'), an operator's platform (4, 4'), a primary drive (5, 5') as well as an undercarriage (6, 6') with propulsion elements (7, 7') are provided, at least one conveyor system (10, 10') which is configured to convey the material, wherein the conveyor system (10, 10') comprises at least one screw conveyor (11, 11'), and the at least one screw conveyor (11, 11') is supported by at least one bearing structure (12, 12'), characterized in that the bearing structure (12, 12') can be heated by at least one heating element (14, 14', 14") which is arranged in a hollow space (18, 18') present inside the bearing structure (12, 12') or provided on an outside of the bearing structure (12, 12').
A prosthesis ( 1a, 1b, 1c) for inguinal hernia repair, for being implanted by endoscopic or open preperitoneal pathway, comprising an openwork textile of a biocompatible material, comprising a first so-called parietal face, for being placed facing the biological tissues of the inguinal region, and a second so-called peritoneal face, opposite to said first face, for being placed facing the peritoneum and the anterior face of the bladder, characterised in that the peritoneal face comprises, on part of its surface, a first zone ( 6, 10, 20) provided with an anti-adherent coating, the parietal face comprising, on part of its surface, a second zone (7,11 21) provided with a non-adherent coating, the prosthesis being rectangular in shape, comprising an upper longitudinal edge, a lower longitudinal edge, and two side edges (4, 5), the first zone extending over the entire width of the prosthesis from a side edge of the prosthesis, the second zone extending over a width of between one-third and one-half of the width of the prosthesis, the first zone and the second zone not being arranged substantially vertically to one another when the prosthesis is seen in a plane view.
A method of calibrating an acoustic monitoring system of an additive manufacturing machine, the method comprising: generating acoustic waves from one or more calibrated acoustic sources from one or more fixed positions in the additive manufacturing machine; measuring an acoustic signal of the generated acoustic waves using acoustic sensors or vibration sensors of the acoustic monitoring system; and comparing the measured acoustic signal to a measurement standard for use in calibrating the acoustic monitoring system; characterized by positioning the one or more calibrated acoustic sources in or on a calibration platform; and removably mounting the calibration platform in or on a build platform location of the additive manufacturing machine; wherein mounting the calibration platform in or on the build platform location comprises: aligning one or more alignment features defined on the calibration platform and configured for engaging complementary features defined on the build platform location of the additive manufacturing machine. generating acoustic waves from one or more calibrated acoustic sources from one or more fixed positions in the additive manufacturing machine; measuring an acoustic signal of the generated acoustic waves using acoustic sensors or vibration sensors of the acoustic monitoring system; and comparing the measured acoustic signal to a measurement standard for use in calibrating the acoustic monitoring system; characterized by positioning the one or more calibrated acoustic sources in or on a calibration platform; and removably mounting the calibration platform in or on a build platform location of the additive manufacturing machine; wherein mounting the calibration platform in or on the build platform location comprises: aligning one or more alignment features defined on the calibration platform and configured for engaging complementary features defined on the build platform location of the additive manufacturing machine.
A method of editing effects in a bitstream carrying video data indicative of a first video sequence, said method comprising: - decoding, the bitstream and a different bitstream to obtain respectively a first decoded video sequence and a second decoded video sequence; - obtaining from the bitstream carrying video data indicative of a first video sequence data indicative of transform coefficients; - obtaining, from the different bitstream carrying video data indicative of a second video sequence further data indicative of a plurality of further transform coefficients; - obtaining predicted video data based on motion vectors from the first decoded video sequence, and on a previously reconstructed frame of the second decoded video sequence; - performing a transform coding on the predicted video data to obtain transformed predicted video data; and - modifying (22, 24, 25) the first video sequence data in the transform domain for providing modified transform coefficients in a valid compressed video bitstream, wherein said modifying (22, 24, 25) comprises combining (22, 22', 24, 25) the obtained data with the obtained further data and the transformed predicted video data. - decoding, the bitstream and a different bitstream to obtain respectively a first decoded video sequence and a second decoded video sequence; - obtaining from the bitstream carrying video data indicative of a first video sequence data indicative of transform coefficients; - obtaining, from the different bitstream carrying video data indicative of a second video sequence further data indicative of a plurality of further transform coefficients; - obtaining predicted video data based on motion vectors from the first decoded video sequence, and on a previously reconstructed frame of the second decoded video sequence; - performing a transform coding on the predicted video data to obtain transformed predicted video data; and - modifying (22, 24, 25) the first video sequence data in the transform domain for providing modified transform coefficients in a valid compressed video bitstream, wherein said modifying (22, 24, 25) comprises combining (22, 22', 24, 25) the obtained data with the obtained further data and the transformed predicted video data.
A digital content data player for playing digital content data, said data player comprising a transmitter for transmitting usage information, the usage information being at least one of the occurrence of the playing or copying of the digital content data, the number of times the digital content data was played or copied, the time the digital content data was played or copied, and the identification of a user that plays or copies the digital content data. characterised in that: the digital content data player is configured to receive said content data comprising a first watermark indicating usage conditions, to check the usage conditions and update the first watermark and to add to the received content data a second watermark to identify purchaser and purchase transaction of the content data. the occurrence of the playing or copying of the digital content data, the number of times the digital content data was played or copied, the time the digital content data was played or copied, and the identification of a user that plays or copies the digital content data. characterised in that: the digital content data player is configured to receive said content data comprising a first watermark indicating usage conditions, to check the usage conditions and update the first watermark and to add to the received content data a second watermark to identify purchaser and purchase transaction of the content data.
A battery packaging material comprising a laminate in which at least a base material layer, a metal layer and a sealant layer are laminated in this order, the laminate satisfying the relationship of A + B ≥ 2.50, where A + B is a sum of a value A of a ratio of a stress in elongation by 40% to a stress in elongation by 10% in the MD direction and a value B of a ratio of a stress in elongation by 40% to a stress in elongation by 10% in the TD direction, measured by a method conforming to JIS K7127, with sample width 15 mm, gauge length 50 mm and tension speed 100 mm/minute.
A Tissue inhibitor of metalloproteinase 2 (TIMP2) polypeptide or fragment thereof, or a nucleic acid composition encoding the TIMP2 polypeptide or fragment thereof for use in the treatment of aging-associated cognitive impairment or decline disease condition in an adult mammal, wherein a TIMP2 activity is enhanced in the mammal in a manner sufficient to treat the adult mammal for the aging-associated cognitive impairment or decline disease condition.
Dispenser for cartridges, comprising a cartridge section for arranging the cartridge, and a handle section, whereby the handle section comprises a housing and a driving mechanism arranged in the housing to drive a driving rod in a longitudinal direction into a cartridge arranged in the cartridge section to exert pressure on a medium stored in the cartridge, the driving mechanism comprising: - a toggle lever with a first lever part, a hinge section and a second lever part, the first lever part pivotably mounted in the housing, the second lever part in operative connection with the driving rod to move the driving rod, and the hinge section pivotably connecting the first lever part and the second lever part around a hinge axis, - a trigger mechanism to provide a driving force for a movement of the driving rod via the toggle lever, and - a transfer mechanism arranged between the trigger mechanism and the toggle lever providing an operative connection between the trigger mechanism and the toggle lever, characterized in that the transfer mechanism comprises an undulating transfer surface with several prominent catches for contacting the hinge section of the toggle lever to provide an operative connection to the toggle lever, whereby an application of the driving force by the trigger mechanism moves the transfer surface in a driving direction at least partly essentially parallel to the longitudinal direction and the prominent catches of the undulating transfer surface repeatedly move the hinge section perpendicular to the longitudinal direction. - a toggle lever with a first lever part, a hinge section and a second lever part, the first lever part pivotably mounted in the housing, the second lever part in operative connection with the driving rod to move the driving rod, and the hinge section pivotably connecting the first lever part and the second lever part around a hinge axis, - a trigger mechanism to provide a driving force for a movement of the driving rod via the toggle lever, and - a transfer mechanism arranged between the trigger mechanism and the toggle lever providing an operative connection between the trigger mechanism and the toggle lever,
A commercially viable process using biowaste for the extraction of pygeum from Prunus domestica (Indian prunus) comprising the steps of: - Collecting "bio-waste" in the form of stem cuttings/ twigs with leaves removed, obtained during routine "pruning" or trimming process of Prunus domestica - Drying the bio-waste till moisture content is about 10-15% - Powdering the same by pulverization - Extracting the powdered stem material with chlorinated organic solvents or water-alcohol mixture, in ratio of 1:4 at 35-40 °C - Filtering and drying the extract under vacuum at 30 °C to obtain,,pygeum' as a greenish mass with bitter almond smell and in which concentration of total sterols typically calculated as beta-sitosterol, is 15-18% and same has anti-BPH activity. - Collecting "bio-waste" in the form of stem cuttings/ twigs with leaves removed, obtained during routine "pruning" or trimming process of Prunus domestica - Drying the bio-waste till moisture content is about 10-15% - Powdering the same by pulverization - Extracting the powdered stem material with chlorinated organic solvents or water-alcohol mixture, in ratio of 1:4 at 35-40 °C - Filtering and drying the extract under vacuum at 30 °C to obtain,,pygeum' as a greenish mass with bitter almond smell and in which concentration of total sterols typically calculated as beta-sitosterol, is 15-18% and same has anti-BPH activity.
A process for obtaining at least one of fucoidan and laminarin from live, harvested seaweed, wherein said process comprises the steps of: (i) harvesting seaweed comprising fucoidan and laminarin to obtain said live, harvested seaweed, wherein said live, harvested seaweed exudes to form an exudate solution; (ii) collecting said exudate solution after 2 days to 3 weeks of exudation at a temperature below 30°C wherein said fucoidan and laminarin are dissolved in said exudate solution; and (iii) separating said at least one of fucoidan or laminarin from said exudate solution by a filtration process comprising the options of: a) a first filtration step to remove solid debris from said exudate solution followed by a second filtration step to separate said fucoidan from said laminarin, wherein either one or both of the filtrations steps is ultrafiltration; or b) a single ultrafiltration step. (i) harvesting seaweed comprising fucoidan and laminarin to obtain said live, harvested seaweed, wherein said live, harvested seaweed exudes to form an exudate solution; (ii) collecting said exudate solution after 2 days to 3 weeks of exudation at a temperature below 30°C wherein said fucoidan and laminarin are dissolved in said exudate solution; and (iii) separating said at least one of fucoidan or laminarin from said exudate solution by a filtration process comprising the options of: a) a first filtration step to remove solid debris from said exudate solution followed by a second filtration step to separate said fucoidan from said laminarin, wherein either one or both of the filtrations steps is ultrafiltration; or b) a single ultrafiltration step. a) a first filtration step to remove solid debris from said exudate solution followed by a second filtration step to separate said fucoidan from said laminarin, wherein either one or both of the filtrations steps is ultrafiltration; or b) a single ultrafiltration step.
An electrochemical cell, comprising: a negative electrode compartment comprising an anode; a positive electrode compartment for holding an aqueous catholyte solution, the positive electrode compartment comprising a cathode positioned to contact the catholyte solution, wherein the catholyte solution comprises a halide ion or polyhalide ion or pseudohalide ion or sulfide ion or polysulfide ion concentration greater than 3M; a solid alkali ion conductive electrolyte membrane positioned between the negative electrode compartment and the positive electrode compartment; wherein the solid alkali ion conductive electrolyte membrane comprises a material selected from a ceramic NaSICON or NaSICON-type material, a ceramic LiSICON or LiSICON-type material, and a KSICON or KSICON-type material; and wherein the cell functions at an operating temperature of greater than 60° C. a negative electrode compartment comprising an anode; a positive electrode compartment for holding an aqueous catholyte solution, the positive electrode compartment comprising a cathode positioned to contact the catholyte solution, wherein the catholyte solution comprises a halide ion or polyhalide ion or pseudohalide ion or sulfide ion or polysulfide ion concentration greater than 3M; a solid alkali ion conductive electrolyte membrane positioned between the negative electrode compartment and the positive electrode compartment; wherein the solid alkali ion conductive electrolyte membrane comprises a material selected from a ceramic NaSICON or NaSICON-type material, a ceramic LiSICON or LiSICON-type material, and a KSICON or KSICON-type material; and wherein the cell functions at an operating temperature of greater than 60° C.
A fusion protein, comprising: (a) a knottin polypeptide having therein a binding loop for binding to a first target; and (b) a second polypeptide having therein a sequence for binding to a second target, said second polypeptide being an antibody Fc domain, wherein the knottin polypeptide is EETI-II, wherein the knottin polypeptide contains a non- native sequence in its binding loop, wherein the non-native sequence mediates binding to one or more of (a) alpha v beta 3 integrin, (b) alpha v beta 5 integrin, and (c) alpha 5 beta 1 integrin. (a) a knottin polypeptide having therein a binding loop for binding to a first target; and (b) a second polypeptide having therein a sequence for binding to a second target, said second polypeptide being an antibody Fc domain,