An interventional controller operable for controlling an execution of an interventional procedure by an interventional robot operable to be navigated within an anatomical region of a patient and an interventional imaging modality operable for an interventional imaging of the anatomical region of the patient, where the interventional controller is configured to: navigate an anatomical roadmap of the anatomical region of the patient in accordance with an interventional plan, control a navigation of the interventional robot within the anatomical region of the patient in accordance with the navigation by the interventional controller of the anatomical roadmap of the anatomical region, and detect any occurrence of the interventional controller navigating proximately to a critical anatomical location within the anatomical roadmap, and in response to a detection by the interventional controller navigating proximately to the critical anatomical location within the anatomical roadmap: pause the navigation of the interventional robot within anatomical region of the patient, autonomously control an interventional imaging of the anatomical region of the patient by the interventional imaging modality, generate an updated anatomical roadmap of the anatomical region from the imaging of the anatomical region of the patient, navigate the updated anatomical roadmap of the anatomical region of the patient in accordance with the interventional plan, and control a resumed navigation of the interventional robot within the anatomical region of the patient in accordance with the navigation by the interventional controller of the updated anatomical roadmap of the anatomical region. navigate an anatomical roadmap of the anatomical region of the patient in accordance with an interventional plan, control a navigation of the interventional robot within the anatomical region of the patient in accordance with the navigation by the interventional controller of the anatomical roadmap of the anatomical region, and detect any occurrence of the interventional controller navigating proximately to a critical anatomical location within the anatomical roadmap, and in response to a detection by the interventional controller navigating proximately to the critical anatomical location within the anatomical roadmap: pause the navigation of the interventional robot within anatomical region of the patient, autonomously control an interventional imaging of the anatomical region of the patient by the interventional imaging modality, generate an updated anatomical roadmap of the anatomical region from the imaging of the anatomical region of the patient, navigate the updated anatomical roadmap of the anatomical region of the patient in accordance with the interventional plan, and control a resumed navigation of the interventional robot within the anatomical region of the patient in accordance with the navigation by the interventional controller of the updated anatomical roadmap of the anatomical region. pause the navigation of the interventional robot within anatomical region of the patient, autonomously control an interventional imaging of the anatomical region of the patient by the interventional imaging modality, generate an updated anatomical roadmap of the anatomical region from the imaging of the anatomical region of the patient, navigate the updated anatomical roadmap of the anatomical region of the patient in accordance with the interventional plan, and control a resumed navigation of the interventional robot within the anatomical region of the patient in accordance with the navigation by the interventional controller of the updated anatomical roadmap of the anatomical region.