A compound of a formula or a pharmaceutically-acceptable salt thereof: wherein, Z is selected from a group consisting of the following formulae (II-1), (II-2) and (II-3): m and n each indicate 0, 1 or 2; Y represents CR 3 or N, provided that when Y is N, then in (II-2) and (II-3), n is 0 or 2; R 1 represents a C 1-6 alkyl, a C 3-8 cycloalkyl, an aryl or a heteroaryl, wherein the alkyl, the cycloalkyl, the aryl or the heteroaryl may be substituted with a substituent selected from a group consisting of a hydroxy, a cyano, a carboxyl, a sulfo, a halogen, a C 1-6 alkyl, a halo-C 1-6 alkyl, a C 3-8 cycloalkyl, a C 1-6 alkoxy, a halo-C 1-6 alkoxy, an amino (the amino may be mono- or di-substituted with a C 1-6 alkyl, an aryl or a heteroaryl), a carbamoyl (the carbamoyl may be mono- or di-substituted with a C 1-6 alkyl, an aryl or a heteroaryl), a sulfanyl (the sulfanyl may be mono-substituted with a C 1-6 alkyl, an aryl or a heteroaryl), a C 1-6 alkylsulfinyl, an arylsulfinyl, a heteroarylsulfinyl, a C 1-6 alkylsulfonyl, an arylsulfonyl, a heteroarylsulfonyl, a sulfamoyl (the sulfamoyl may be mono- or di-substituted with a C 1-6 alkyl, an aryl or a heteroaryl), a C 1-6 alkylsulfonylamino, an arylsulfonylamino, a heteroarylsulfonylamino, a C 1-6 alkylcarbonyl, an arylcarbonyl, a heteroarylcarbonyl, a C 1-6 alkoxycarbonyl, an aryloxycarbonyl, a heteroaryloxycarbonyl, a carbamoylamino (the carbamoylamino may be mono- or di-substituted with a C 1-6 alkyl, an aryl or a heteroaryl), a C 1-6 alkoxycarbonylamino, an aryloxycarbonylamino, a heteroaryloxycarbonylamino, a C 1-6 alkylcarbonylamino, an arylcarbonylamino, a heteroarylcarbonylamino, an aryl, a heteroaryl, an aralkyl, a heteroaralkyl, an aralkyloxy and a heteroaralkyloxy; R 2 is 2-isopropoxyphenyl, 3-isopropoxyphenyl, 4-isopropoxyphenyl, 5-isopropoxyphenylpyridin-2-yl or 6-isopropoxyphenylpyridin-3-yl; R 3 and R 4 each independently represent a hydrogen atom, a C 1-6 alkyl, a C 3-8 cycloalkyl, an aralkyl, a heteroaralkyl, an aryl or a heteroaryl, wherein the alkyl, the cycloalkyl, the aralkyl, the heteroaralkyl, the aryl or the heteroaryl may be substituted with a substituent selected from a group consisting of a halogen, a C 1-6 alkyl, a halo-C 1-6 alkyl, a C 1-6 alkoxy and a halo-C 1-6 alkoxy; M 1, M 2, M 3 and M 4 each independently represent a hydrogen atom, or a C 1-6 alkyl optionally substituted with a halogen; or M 1, taken together with M 2, M 3 or M 4, forms - CH 2 - or -CH 2 -CH 2 -, or M 4, taken together with M 2, forms -CH 2 - or -CH 2 -CH 2 m and n each indicate 0, 1 or 2; Y represents CR 3 or N, provided that when Y is N, then in (II-2) and (II-3), n is 0 or 2; R 1 represents a C 1-6 alkyl, a C 3-8 cycloalkyl, an aryl or a heteroaryl, wherein the alkyl, the cycloalkyl, the aryl or the heteroaryl may be substituted with a substituent selected from a group consisting of a hydroxy, a cyano, a carboxyl, a sulfo, a halogen, a C 1-6 alkyl, a halo-C 1-6 alkyl, a C 3-8 cycloalkyl, a C 1-6 alkoxy, a halo-C 1-6 alkoxy, an amino (the amino may be mono- or di-substituted with a C 1-6 alkyl, an aryl or a heteroaryl), a carbamoyl (the carbamoyl may be mono- or di-substituted with a C 1-6 alkyl, an aryl or a heteroaryl), a sulfanyl (the sulfanyl may be mono-substituted with a C 1-6 alkyl, an aryl or a heteroaryl), a C 1-6 alkylsulfinyl, an arylsulfinyl, a heteroarylsulfinyl, a C 1-6 alkylsulfonyl, an arylsulfonyl, a heteroarylsulfonyl, a sulfamoyl (the sulfamoyl may be mono- or di-substituted with a C 1-6 alkyl, an aryl or a heteroaryl), a C 1-6 alkylsulfonylamino, an arylsulfonylamino, a heteroarylsulfonylamino, a C 1-6 alkylcarbonyl, an arylcarbonyl, a heteroarylcarbonyl, a C 1-6 alkoxycarbonyl, an aryloxycarbonyl, a heteroaryloxycarbonyl, a carbamoylamino (the carbamoylamino may be mono- or di-substituted with a C 1-6 alkyl, an aryl or a heteroaryl), a C 1-6 alkoxycarbonylamino, an aryloxycarbonylamino, a heteroaryloxycarbonylamino, a C 1-6 alkylcarbonylamino, an arylcarbonylamino, a heteroarylcarbonylamino, an aryl, a heteroaryl, an aralkyl, a heteroaralkyl, an aralkyloxy and a heteroaralkyloxy; R 2 is 2-isopropoxyphenyl, 3-isopropoxyphenyl, 4-isopropoxyphenyl, 5-isopropoxyphenylpyridin-2-yl or 6-isopropoxyphenylpyridin-3-yl; R 3 and R 4 each independently represent a hydrogen atom, a C 1-6 alkyl, a C 3-8 cycloalkyl, an aralkyl, a heteroaralkyl, an aryl or a heteroaryl, wherein the alkyl, the cycloalkyl, the aralkyl, the heteroaralkyl, the aryl or the heteroaryl may be substituted with a substituent selected from a group consisting of a halogen, a C 1-6 alkyl, a halo-C 1-6 alkyl, a C 1-6 alkoxy and a halo-C 1-6 alkoxy; M 1, M 2, M 3 and M 4 each independently represent a hydrogen atom, or a C 1-6 alkyl optionally substituted with a halogen; or M 1, taken together with M 2, M 3 or M 4, forms - CH 2 - or -CH 2 -CH 2 -, or M 4, taken together with M 2, forms -CH 2 - or -CH 2 -CH 2