A compound of Formula: or a solvate, or pharmaceutically acceptable salt thereof, wherein: R 1 is C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyl, or C 3 -C 6 cycloalkyl; R 2 is C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyl, or C 3 -C 6 cycloalkyl; or R 1 and R 2 together with the atoms to which they are attached form a C 3 -C 6 saturated or partially unsaturated cycloalkyl or a 3- to 14-membered saturated or partially unsaturated heterocycle comprising 1-5 heteroatoms selected from N, O, and S; R 3 is H, halogen, -S(C 1 -C 6 alkyl), -N(C 1- C 6 alkyl) 2, -NH(C 1- C 6 alkyl), -NH 2, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyl, C 1 -C 6 haloalkoxyl, or C 3 -C 6 cycloalkyl; R 4 is H, halogen, -S(C 1 -C 6 alkyl), -N(C 1- C 6 alkyl) 2, -NH(C 1- C 6 alkyl), -NH 2, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyl, C 1 -C 6 haloalkoxyl, or C 3 -C 6 cycloalkyl; R 5 is H, halogen, -S(C 1 -C 6 alkyl), -N(C 1- C 6 alkyl) 2, -NH(C 1- C 6 alkyl), -NH 2, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyl, C 1 -C 6 haloalkoxyl, or C 3 -C 6 cycloalkyl; R 6 is H, halogen, -S(C 1 -C 6 alkyl), -N(C 1- C 6 alkyl) 2, -NH(C 1- C 6 alkyl), -NH 2, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyl, C 1 -C 6 haloalkoxyl, or C 3 -C 6 cycloalkyl; R 7 is H, deuterium, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, or C 2 -C 6 alkynyl; R 8 is H, deuterium, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, or C 2 -C 6 alkynyl; and R 9 is H, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, or C 3 -C 6 cycloalkyl, provided that at least one of R 3, R 4, R 5, and R 6 is H. R 1 is C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyl, or C 3 -C 6 cycloalkyl; R 2 is C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyl, or C 3 -C 6 cycloalkyl; or R 1 and R 2 together with the atoms to which they are attached form a C 3 -C 6 saturated or partially unsaturated cycloalkyl or a 3- to 14-membered saturated or partially unsaturated heterocycle comprising 1-5 heteroatoms selected from N, O, and S; R 3 is H, halogen, -S(C 1 -C 6 alkyl), -N(C 1- C 6 alkyl) 2, -NH(C 1- C 6 alkyl), -NH 2, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyl, C 1 -C 6 haloalkoxyl, or C 3 -C 6 cycloalkyl; R 4 is H, halogen, -S(C 1 -C 6 alkyl), -N(C 1- C 6 alkyl) 2, -NH(C 1- C 6 alkyl), -NH 2, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyl, C 1 -C 6 haloalkoxyl, or C 3 -C 6 cycloalkyl; R 5 is H, halogen, -S(C 1 -C 6 alkyl), -N(C 1- C 6 alkyl) 2, -NH(C 1- C 6 alkyl), -NH 2, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyl, C 1 -C 6 haloalkoxyl, or C 3 -C 6 cycloalkyl; R 6 is H, halogen, -S(C 1 -C 6 alkyl), -N(C 1- C 6 alkyl) 2, -NH(C 1- C 6 alkyl), -NH 2, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyl, C 1 -C 6 haloalkoxyl, or C 3 -C 6 cycloalkyl; R 7 is H, deuterium, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, or C 2 -C 6 alkynyl; R 8 is H, deuterium, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, or C 2 -C 6 alkynyl; and R 9 is H, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, or C 3 -C 6 cycloalkyl, provided that at least one of R 3, R 4, R 5, and R 6 is H.