A pipette tip coupling device (100, 400) and pipette tip assembly comprising: a pipette tip comprising a circumscribing sidewall with an open interior passage including an interior surface and extending along a central longitudinal axis of the pipette tip between an open proximal end and an open distal end of the pipette tip; a pipette tip coupling device (100, 400) is provided comprising: a shank having a proximal end face; a coupler body distal to the shank; wherein a diameter of a widest portion of the coupler body is greater than a diameter of a widest portion of the shank; a distal stem portion; a distal end plate; an open-ended interior circumscribing surface forming an open passageway extending longitudinally from the proximal end face through the distal end plate; an elastomeric element disposed around the distal stem portion and adjacent to the distal end plate; characterized in that a pipette tip ball assembly is provided which circumscribes the shank comprising: a plurality of spherical balls; and a ring-shaped raceway body comprising: a plurality of circumferentially spaced apart guide sockets for carrying the plurality of spherical balls; and a plurality of circumferentially spaced apart circular ball openings for receiving and retaining the plurality of spherical balls. a pipette tip comprising a circumscribing sidewall with an open interior passage including an interior surface and extending along a central longitudinal axis of the pipette tip between an open proximal end and an open distal end of the pipette tip; a pipette tip coupling device (100, 400) is provided comprising: a shank having a proximal end face; a coupler body distal to the shank; wherein a diameter of a widest portion of the coupler body is greater than a diameter of a widest portion of the shank; a distal stem portion; a distal end plate; an open-ended interior circumscribing surface forming an open passageway extending longitudinally from the proximal end face through the distal end plate; an elastomeric element disposed around the distal stem portion and adjacent to the distal end plate; a shank having a proximal end face; a coupler body distal to the shank; wherein a diameter of a widest portion of the coupler body is greater than a diameter of a widest portion of the shank; a distal stem portion; a distal end plate; an open-ended interior circumscribing surface forming an open passageway extending longitudinally from the proximal end face through the distal end plate; an elastomeric element disposed around the distal stem portion and adjacent to the distal end plate; characterized in that a pipette tip ball assembly is provided which circumscribes the shank comprising: a plurality of spherical balls; and a ring-shaped raceway body comprising: a plurality of circumferentially spaced apart guide sockets for carrying the plurality of spherical balls; and a plurality of circumferentially spaced apart circular ball openings for receiving and retaining the plurality of spherical balls. a plurality of spherical balls; and a ring-shaped raceway body comprising: a plurality of circumferentially spaced apart guide sockets for carrying the plurality of spherical balls; and a plurality of circumferentially spaced apart circular ball openings for receiving and retaining the plurality of spherical balls. a plurality of circumferentially spaced apart guide sockets for carrying the plurality of spherical balls; and a plurality of circumferentially spaced apart circular ball openings for receiving and retaining the plurality of spherical balls.