mhurhangee/ep-ind-claims huggingface dataset:
A pharmaceutical composition for use in preventing and treating hypertension caused by renin, aldosteronism, adrenoleukodystrophy, glomerulosclerosis, proteinuria, nephropathy, liver steatosis, hypertriglyceridemia, or hyperreninemia, caused by the overexpression or overactivity of a liver X receptor alpha(LXRα), wherein the pharmaceutical composition contains as an effective component a compound represented by Formula 1 below, a pharmaceutically acceptable salt thereof, a solvate thereof, or a hydrate thereof: where X is carbon or nitrogen, Q is sulfur, oxygen, or -S=O, and R 1 and R 2 are each independently selected from the group consisting of a hydrogen atom, C 1-7 -alkyl, C 3-7 -cycloalkyl, C 1-7 -haloalkyl, C 1-7 -alkoxy, C 3-7 -cycloalkoxy, C 1-7 -alkylthio, C 3-7 -cycloalkylthio, C 1-7 -alkenyl, C 1-7 -alkynyl, C 1-7 -alkylsulfonyl, C 1-7 -alkylaminocarbonyl, HO-C 1-7 -alkyl, HS-C 1-7 -alkyl, hydroxy, thiol, halogen, carboxyl, nitro, cyano, C 1-7 -alkylcarbonyl, C 1-7 -alkoxycarbonyl, C 1-7 -alkylcarbonyloxy, C 1-4 -alkylcarbonyl-C 1-4 -alkyl, C 1-4 -alkoxy-C 1-4 -alkyl, C 1-4 -alkylthio-C 1-4 -alkyl, amino, C 1-7 -alkylamino, C 1-7 -alkylcarbonylamino, C 1-4 -alkoxy-C 1-4 -alkylamino, C 1-4 -alkylthio-C 1-4 -alkylamino, C 1-4 -alkylsulfoneamino, phenyl, heteroaryl, phenyl-C 1-4 -alkyl, heteroaryl-C 1-4 -alkyl, phenyl-C 1-4 -alkoxy-C 1-4 -alkyl, phenyl-C 1-4 -alkylthio-C 1-4 -alkyl, phenoxy-C 1-4 -alkyl, phenylthio-C 1-4 -alkyl, phenylcarbonylamino, phenoxy-C 1-4 -alkylcarbonylamino, phenyl-C 1-4 -alkoxy-C 1-4 -alkylcarbonylamino, heteroaryloxy-C 1-4 -alkyl, heteroarylthio-C 1-4 -alkyl, and heteroaryl-C 1-4 -alkylthio-C 1-4 -alkyl, wherein the heteroaryl refers to a 5 or 6-membered cyclic compound that contains at least one hetero atom selected from the group consisting of nitrogen, sulfur, and oxygen; the phenyl and heteroaryl is substituted or unsubstituted and an available substituent is selected from the group consisting of halogen, C 1-7 -alkyl, C 1-7 -alkoxy, C 1-7 -haloalkyl, C 1-7 -alkylthio, C 1-7 -alkenyloxy, C 1-4 -alkylcarbonyl, C 1-4 -alkylamino, nitro, amino, cyano, HO-C 1-4 -alkyl, HS-C 1-4 -alkyl, HO-C 1-7 -alkoxy, HO-C 1-7 -alkylthio, HS-C 1-7 -alkylthio, HS-C 1-7 -alkoxy, thiol, hydroxy, and carboxyl, and when substituted, the phenyl and heteroaryl is mono-substituted or multisubstituted; the phenyl and heteroaryl is each independently fused with at least one benzene or the heteroaryl described above; and the fused phenyl and heteroaryl is substituted or unsubstituted and an available substituent is selected from the group consisting of halogen, C 1-7 -alkyl, C 1-7 -oralkoxy, C 1-7 -haloalkyl, C 1-7 -alkylthio, C 1-7 -alkenyloxy, C 1-4 -alkylcarbonyl, C 1-4 -alkylamino, nitro, amino, cyano, HO-C 1-4 -alkyl, HS-C 1-4 -alkyl, HO-C 1-7 -ralkoxy, HO-C 1-7 -ralkylthio, HS-C 1-7 -alkylthio, HS-C 1-7 -alkoxy, thiol, hydroxy, and carboxyl, and when substituted, the phenyl and heteroaryl is mono-substituted or multi-substituted.
Process for producing a galvannealed zinc-magnesium hot dip coating on a steel substrate, comprising the following work steps: a) providing a steel substrate comprising an IF steel, b) hot dip coating of the steel substrate in an Fe-saturated melt bath heated to a bath temperature of 350-650°C, consisting of (in wt.-%) 0.10-0.16 % Al, 0.1-0.6% Mg and 0.01-0.5% Fe and in each case optionally < 2% Si, < 0.1% Pb, < 0.2% Ti, < 1 % Ni, 0.3% Co, < 0.0001% Mn, < 0.2% Cr, < 0.5% Sr, < 0.1 % Bi, < 0.1% Cd and < 0.5% Sn, the remainder being zinc and unavoidable impurities from the production, and c) performing a galvannealing treatment in which the hot dip-coated steel substrate is kept at a galvannealing temperature of 540-800°C for a galvannealing time of 10-25 s in order to produce a galvannealed zinc-magnesium hot dip coating on the steel substrate, comprising in addition to zinc and unavoidable impurities (in wt.-%) 0.10-0.5% Al, 5.0-15.0% Fe, 0.10-0.8% Mg and optionally one or more of the following elements with the following proviso regarding their contents: Si: < 2%, Pb: < 0.1%, Ti: < 0.2%, Ni: < 1%, Co: < 0.3%, Mn: < 0.0001%, Cr: < 0.2%, Sr: < 0.5%, Bi: < 0.1%, Cd:< 0.1%, Sn < 0.01%. a) providing a steel substrate comprising an IF steel, b) hot dip coating of the steel substrate in an Fe-saturated melt bath heated to a bath temperature of 350-650°C, consisting of (in wt.-%) 0.10-0.16 % Al, 0.1-0.6% Mg and 0.01-0.5% Fe and in each case optionally < 2% Si, < 0.1% Pb, < 0.2% Ti, < 1 % Ni, 0.3% Co, < 0.0001% Mn, < 0.2% Cr, < 0.5% Sr, < 0.1 % Bi, < 0.1% Cd and < 0.5% Sn, the remainder being zinc and unavoidable impurities from the production, and c) performing a galvannealing treatment in which the hot dip-coated steel substrate is kept at a galvannealing temperature of 540-800°C for a galvannealing time of 10-25 s in order to produce a galvannealed zinc-magnesium hot dip coating on the steel substrate, comprising in addition to zinc and unavoidable impurities (in wt.-%) 0.10-0.5% Al, 5.0-15.0% Fe, 0.10-0.8% Mg and optionally one or more of the following elements with the following proviso regarding their contents: Si: < 2%, Pb: < 0.1%, Ti: < 0.2%, Ni: < 1%, Co: < 0.3%, Mn: < 0.0001%, Cr: < 0.2%, Sr: < 0.5%, Bi: < 0.1%, Cd:< 0.1%, Sn < 0.01%.
Switchmode power supply comprising: a transformer having a primary-side main winding (W3-1) and a secondary-side main winding (W3-3), a primary-side switch for interrupting a primary-side current that flows through the primary-side main winding (W3-1), a feedback unit (W3-2) which is operable to generate an auxiliary voltage that is a function of a secondary-side output voltage (V out), a control circuit for controlling said primary-side switch, the control circuit comprising an output voltage regulator unit that is operable to reduce the primary-side current flow in response to a sensed value (V aux) of the auxiliary voltage and to perform a foldback current limiting, characterized in that the control circuit further comprises a voltage regulation deactivating unit that is connected to a voltage measurement input of the output voltage regulator unit and is operable to increase the sensed value (V aux) of the auxiliary voltage received by the output voltage regulator unit, when the output voltage reaches a defined lower threshold. a transformer having a primary-side main winding (W3-1) and a secondary-side main winding (W3-3), a primary-side switch for interrupting a primary-side current that flows through the primary-side main winding (W3-1), a feedback unit (W3-2) which is operable to generate an auxiliary voltage that is a function of a secondary-side output voltage (V out), a control circuit for controlling said primary-side switch, the control circuit comprising an output voltage regulator unit that is operable to reduce the primary-side current flow in response to a sensed value (V aux) of the auxiliary voltage and to perform a foldback current limiting, characterized in that the control circuit further comprises a voltage regulation deactivating unit that is connected to a voltage measurement input of the output voltage regulator unit and is operable to increase the sensed value (V aux) of the auxiliary voltage received by the output voltage regulator unit, when the output voltage reaches a defined lower threshold.
A data processing network protocol bridging system comprising: a bridging device configured to receive data in two different protocols, to extract implicit message data from the received data, and to compile output data in both protocols; a memory circuit configured to store data extracted by the bridging device; and characterized by a programmable logic circuit configured to determine first data of the implicit message on which logical operations are not to be performed, determine second data of the implicit message on which logical operations are to be performed, and execute logical operations on the second data to produce processed data to be included in the output data along with the first data on which logical operations are not executed. a bridging device configured to receive data in two different protocols, to extract implicit message data from the received data, and to compile output data in both protocols; a memory circuit configured to store data extracted by the bridging device; and characterized by a programmable logic circuit configured to determine first data of the implicit message on which logical operations are not to be performed, determine second data of the implicit message on which logical operations are to be performed, and execute logical operations on the second data to produce processed data to be included in the output data along with the first data on which logical operations are not executed.
Electronic control casing (1; 1'; 1") of a home automation closure, blanking, solar protection, comfort, security or screening equipment item, comprising a first casing part (2; 2") containing a receiver of commands and a control unit of said equipment item, the receiver of commands and the control unit being produced on one or more electronic circuit boards and contained in a unit mounted on a bottom of the first casing part, the casing comprising a second part in the form of a cap intended to cooperate with the first part and to close the casing, the first casing part comprising a mechanical link element (5; 5'; 5") for linking to at least one remote control intended to communicate with the receiver of commands, the mechanical link element making it possible to mechanically link or secure the remote control(s) to the first casing part, the mechanical link element comprising a housing and the second part comprising a holding element for holding the remote control(s) in the housing when the second casing part is mounted on the first casing part.
A method for lightfield volume rendering, the method comprising: rendering, by a physically-based renderer and from a medical dataset representing a three-dimensional region of a patient, a lightfield representing the three-dimensional region of the patient in two dimensions; assigning depths to locations in the lightfield, wherein assigning comprises, for each pixel of the rendered lightfield, locating a depth with clustering of sampling points used by the physically-based renderer in rendering the pixels, and wherein locating the depth with clustering comprises binning depths for the sampling points in a histogram and selecting the depth with a greatest number of hits in the histogram, further comprising using multiple depth histograms and sub-dividing the depth histograms, wherein after M rendering passes have been performed in physically-based rendering for the ray, the bin with most hits is subdivided into N bins again and the hits in other bins are discarded, wherein this sub-division may proceed until convergence or a given number of iterations and wherein the depths in the bin of the final histogram with the highest number of hits are then averaged to compute the depth at that pixel position; rendering, by a lightfield renderer, another image representing the three-dimensional region of the patient from the lightfield and depths; and transmitting the other image. rendering, by a physically-based renderer and from a medical dataset representing a three-dimensional region of a patient, a lightfield representing the three-dimensional region of the patient in two dimensions; assigning depths to locations in the lightfield, wherein assigning comprises, for each pixel of the rendered lightfield, locating a depth with clustering of sampling points used by the physically-based renderer in rendering the pixels, and wherein locating the depth with clustering comprises binning depths for the sampling points in a histogram and selecting the depth with a greatest number of hits in the histogram, further comprising using multiple depth histograms and sub-dividing the depth histograms, wherein after M rendering passes have been performed in physically-based rendering for the ray, the bin with most hits is subdivided into N bins again and the hits in other bins are discarded, wherein this sub-division may proceed until convergence or a given number of iterations and wherein the depths in the bin of the final histogram with the highest number of hits are then averaged to compute the depth at that pixel position; rendering, by a lightfield renderer, another image representing the three-dimensional region of the patient from the lightfield and depths; and transmitting the other image.
A body coupled communication apparatus comprising a transmitter module and a receiver module, the transmitter module including a transmitter (Tx) having outputs coupled to a pair of mutually opposed transmitter plates (Tx1, Tx2) to provide a transmission signal, said transmitter plates having a first area and a first mutual distance, the receiver module including receiver (Rx) coupled to a pair of mutually opposed receiver plates (Rx1, Rx2), to receive a reception signal, said receiver plates having a second area and a second mutual distance D2, wherein a ratio (A1*D2) / (A2*D1) is at least 2 and characterised in that the transmitter module and the receiver module are integrated in a carrier having a main surface, and wherein the pair of mutually opposed transmitter plates is aligned with the main surface of the carrier, and the pair of mutually opposed receiver plates is arranged transverse to the main surface at mutually opposite ends of the carrier.
A water-tight light-emitting diode module comprising:- a base plate; a printed circuit board mounted on the base plate; a plurality of light-emitting diodes mounted on the printed circuit board; at least two electrical connections (240, 250) mounted on the printed circuit board and electrically connected for supplying power to each of the plurality of light-emitting diodes; a secondary lens array mounted over the plurality of light-emitting diodes on the printed circuit board, the secondary lens array comprising a plurality of secondary lens elements; and a lens holder mounted over the secondary lens array, the lens holder comprising a plurality of apertures formed therein for accommodating a respective one of the secondary lens elements, characterized in that the secondary lens array is configured to provide a cover portion (340, 350) for each of the electrical connections (240, 250) and a sheath portion (345, 355) for each wire being connected to each of the electrical connections (240, 250), and the lens holder is configured to compress at least one portion of the secondary lens array to form at least one gasket between the lens holder and the base plate to prevent the ingress of water around the printed circuit board. a base plate; a printed circuit board mounted on the base plate; a plurality of light-emitting diodes mounted on the printed circuit board; at least two electrical connections (240, 250) mounted on the printed circuit board and electrically connected for supplying power to each of the plurality of light-emitting diodes; a secondary lens array mounted over the plurality of light-emitting diodes on the printed circuit board, the secondary lens array comprising a plurality of secondary lens elements; and a lens holder mounted over the secondary lens array, the lens holder comprising a plurality of apertures formed therein for accommodating a respective one of the secondary lens elements, the secondary lens array is configured to provide a cover portion (340, 350) for each of the electrical connections (240, 250) and a sheath portion (345, 355) for each wire being connected to each of the electrical connections (240, 250), and the lens holder is configured to compress at least one portion of the secondary lens array to form at least one gasket between the lens holder and the base plate to prevent the ingress of water around the printed circuit board.
Method for processing echoes in a telephony and/or videophony equipment item, equipment item in which a strong echo is likely to result from an interaction between at least one loudspeaker and at least one microphone (Mic) of said equipment item, the method comprising a first general step, of detection of a risk of echo, followed by a second general step (20, 40), of processing including the suppression or, at least, the limitation of an echo effect, said first general step comprising at least the detection of a strong onset, above a predetermined threshold, on a signal powering the loudspeaker, in which said first step, for the detection of a risk of strong echo, comprises, together with said detection of strong onset on the signal powering the loudspeaker, a detection of a low level, below a chosen threshold, of a signal from said microphone, characterized in that said detection of strong onset on the signal powering the loudspeaker comprises at least the tracking of a level of peaks (CRET_HP) of the signal powering the loudspeaker, and the detection of a strong onset being effective at least if said level of peaks (CRET_HP) is above a predetermined level-of-peaks threshold (THR_CRET_HP).
A linear lamp having a support profile, an optics, and a lighting means, wherein the lighting means includes multiple boards, each with a front surface and a rear surface and a plurality of light emitting diodes mounted on the front surface, the multiple boards each being equipped with current paths via which the light emitting diodes may be supplied with power, the support profile and the optics each have corresponding mounting means (43, 53) so that the optics is mountable on the support profile, the optics at least partially covers the light emitting diodes of the lighting means when the optics and the lighting means are mounted on the profile, the linear lamp includes a coupling adapter that connects the current paths of two adjacent boards of the multiple boards to one another when the lighting means is mounted on the support profile, wherein the coupling adapter includes a support profile part and two board parts, and the support profile part is mounted on the support profile, characterized in that a first of the two board parts is fastened to the rear surface of one of the adjacent boards of the multiple boards, and a second of the two board parts is fastened to the rear surface of the other of the two adjacent boards of the multiple boards, so that the two board parts are connected to the support profile part when the lighting means is mounted on the support profile, and so that a coupling perpendicular to the surfaces (21; 26) of the board is provided for the power supply of the boards. the lighting means includes multiple boards, each with a front surface and a rear surface and a plurality of light emitting diodes mounted on the front surface, the multiple boards each being equipped with current paths via which the light emitting diodes may be supplied with power, the support profile and the optics each have corresponding mounting means (43, 53) so that the optics is mountable on the support profile, the optics at least partially covers the light emitting diodes of the lighting means when the optics and the lighting means are mounted on the profile, the linear lamp includes a coupling adapter that connects the current paths of two adjacent boards of the multiple boards to one another when the lighting means is mounted on the support profile, wherein the coupling adapter includes a support profile part and two board parts, and the support profile part is mounted on the support profile, characterized in that a first of the two board parts is fastened to the rear surface of one of the adjacent boards of the multiple boards, and a second of the two board parts is fastened to the rear surface of the other of the two adjacent boards of the multiple boards, so that the two board parts are connected to the support profile part when the lighting means is mounted on the support profile, and so that a coupling perpendicular to the surfaces (21; 26) of the board is provided for the power supply of the boards.
Method for measuring the activity of enzymes in a sample which contains at least one enzyme and at least one enzyme inhibitor corresponding to said enzyme, whereby after removing the inhibitor the activity of the freed enzyme is measured in such a way that a substrate is added to the sample and the time course of the concentration of at least one reaction product, in particular of a cleavage product is recorded and the enzyme specific substrate has a fluorogenic part which is cleaved in the enzymatic reaction and the fluorescence of which can be detected as a measuring parameter in a wavelength range where the measuring parameter can be assigned unambiguously to the enzyme activity to be measured, characterized in that the removing of the inhibitor is carried out by immersing into the sample a rigid carrier to which the inhibitor binding substance is bound.
Method for producing a pressure hose having the steps: - injection moulding of a tubular first hose element, - mounting of a fabric hose on the outside of the first hose element, - shrinking of the fabric hose on the first hose element and - injection moulding of a tubular second hose element around the first hose element and the fabric hose mounted thereabove. - injection moulding of a tubular first hose element, - mounting of a fabric hose on the outside of the first hose element, - shrinking of the fabric hose on the first hose element and - injection moulding of a tubular second hose element around the first hose element and the fabric hose mounted thereabove.
A profile connecting molding for a transition between a building component and a wall, wherein said molding comprises a foam tape connected directly or indirectly by adhesive bonding to the molding and to the building component and is connectable directly or indirectly to the building component and for equalizing an elevated relative movement between the molding and the building component comprises an elevated elasticity, characterized in that said foam tape for equalizing an elevated relative movement between the molding and the building component comprises an elevated ultimate elongation, said foam tape comprising an ultimate elongation in the longitudinal direction of the molding of at least 200% and particularly at least 300% and/or an ultimate elongation in the transverse direction of the molding of at least 200% and particularly at least 300%.
A coated composite material comprising: a composite substrate comprising a polymeric matrix with fibre reinforcement; a surface of the composite substrate being coated with: (i) a two-phase primer layer comprising a reinforcing phase of material elements bound in a predefined distribution by a polymeric phase and at least partially exposed at an outer surface of the primer layer so as to provide a surface texture; and (ii) a coating layer adhered to said outer surface of the two-phase primer layer. a composite substrate comprising a polymeric matrix with fibre reinforcement; a surface of the composite substrate being coated with: (i) a two-phase primer layer comprising a reinforcing phase of material elements bound in a predefined distribution by a polymeric phase and at least partially exposed at an outer surface of the primer layer so as to provide a surface texture; and (ii) a coating layer adhered to said outer surface of the two-phase primer layer. (i) a two-phase primer layer comprising a reinforcing phase of material elements bound in a predefined distribution by a polymeric phase and at least partially exposed at an outer surface of the primer layer so as to provide a surface texture; and (ii) a coating layer adhered to said outer surface of the two-phase primer layer.