A medical sampling device for use with an endoscope or catheter for flushing of a body cavity and/or for sampling of bodily fluids and/or bodily tissue, the endoscope or catheter having a suction channel and a suction connector in fluid communication with said suction channel, the sampling device comprising a suction inlet for connection to the suction connector, a suction outlet for connection to a vacuum source, a sampling outlet for connection to a sample container, a sampling inlet for connection to the sample container, and a valve having a valve member and a valve housing, wherein the valve member has a first and a second chamber (10A, 10B) and is rotatable in relation to the valve housing between a first and a second position, the first chamber in the first position establishing fluid communication between the suction inlet and the sampling inlet, the second chamber in the first position establishing fluid communication between the sampling outlet and the suction outlet, one of the first and the second chamber (10A, 10B) in the second position establishing fluid communication between the suction inlet and the suction outlet, the valve member being rotatable about an axis defining an axial direction, characterized in that a first valve port connected to the suction inlet and/or a second valve port connected to the sampling outlet and/or a third valve port connected to the suction outlet and/or a fourth valve port connected to the sampling inlet is/are provided in a valve housing surface extending radially in relation to the axial direction, wherein at least one of the first and second chambers (10A, 10B) comprises at least one top opening (111A, 111B) providing said fluid communication between the respective inlets and outlets in the first and second positions of the valve member via the respective first and second chambers (10A, 10B), and wherein this top opening (111A, 111B) is suitably aligned with the relevant valve ports in the first and second positions of the valve member. the sampling device comprising a suction inlet for connection to the suction connector, a suction outlet for connection to a vacuum source, a sampling outlet for connection to a sample container, a sampling inlet for connection to the sample container, and a valve having a valve member and a valve housing, wherein the valve member has a first and a second chamber (10A, 10B) and is rotatable in relation to the valve housing between a first and a second position, the first chamber in the first position establishing fluid communication between the suction inlet and the sampling inlet, the second chamber in the first position establishing fluid communication between the sampling outlet and the suction outlet, one of the first and the second chamber (10A, 10B) in the second position establishing fluid communication between the suction inlet and the suction outlet, the valve member being rotatable about an axis defining an axial direction, characterized in that a first valve port connected to the suction inlet and/or a second valve port connected to the sampling outlet and/or a third valve port connected to the suction outlet and/or a fourth valve port connected to the sampling inlet is/are provided in a valve housing surface extending radially in relation to the axial direction, wherein at least one of the first and second chambers (10A, 10B) comprises at least one top opening (111A, 111B) providing said fluid communication between the respective inlets and outlets in the first and second positions of the valve member via the respective first and second chambers (10A, 10B), and wherein this top opening (111A, 111B) is suitably aligned with the relevant valve ports in the first and second positions of the valve member. wherein at least one of the first and second chambers (10A, 10B) comprises at least one top opening (111A, 111B) providing said fluid communication between the respective inlets and outlets in the first and second positions of the valve member via the respective first and second chambers (10A, 10B), and wherein this top opening (111A, 111B) is suitably aligned with the relevant valve ports in the first and second positions of the valve member.