A culture apparatus comprising: a heat-insulated casing including an inner case surrounding a culture space, an outer case surrounding the inner case, and a front surface, the heat-insulated casing having an opening in the front surface; a box-shaped heat-insulated door configured to open and close the opening of the heat-insulated casing; one or more heaters provided to one or more inner surfaces of the inner case and an inner wall surface of the heat-insulated door and configured to heat the culture space, the inner wall surface being adapted to face the culture space when the door is closed; and a control unit configured for turning on the heaters, the heaters including one or more first heaters and one or more second heaters, characterized in that the control unit is further configured so that the first heaters are turned on, when a temperature of the culture space is controlled to a first temperature to incubate a culture in the culture space and when a temperature of the culture space is controlled to a second temperature to make the culture space sterile, the second temperature being higher than the first temperature, and the second heaters are turned on when a temperature of the culture space is controlled to the second temperature to make the culture space sterile. a heat-insulated casing including an inner case surrounding a culture space, an outer case surrounding the inner case, and a front surface, an inner case surrounding a culture space, an outer case surrounding the inner case, and a front surface, the heat-insulated casing having an opening in the front surface; a box-shaped heat-insulated door configured to open and close the opening of the heat-insulated casing; one or more heaters provided to one or more inner surfaces of the inner case and an inner wall surface of the heat-insulated door and configured to heat the culture space, the inner wall surface being adapted to face the culture space when the door is closed; and a control unit configured for turning on the heaters, the heaters including one or more first heaters and one or more second heaters, characterized in that the control unit is further configured so that the first heaters are turned on, when a temperature of the culture space is controlled to a first temperature to incubate a culture in the culture space and when a temperature of the culture space is controlled to a second temperature to make the culture space sterile, the second temperature being higher than the first temperature, and the second heaters are turned on when a temperature of the culture space is controlled to the second temperature to make the culture space sterile. one or more first heaters and one or more second heaters, characterized in that the control unit is further configured so that the first heaters are turned on, when a temperature of the culture space is controlled to a first temperature to incubate a culture in the culture space and when a temperature of the culture space is controlled to a second temperature to make the culture space sterile, the second temperature being higher than the first temperature, and the second heaters are turned on when a temperature of the culture space is controlled to the second temperature to make the culture space sterile.