A high-safety LED tube, comprising: a first side having a first electrode and a second electrode; a second side having a third electrode and a fourth electrode; characterized in further comprising: a first impedance module coupled to the first electrode and the second electrode, and including a first impedance unit and a second impedance unit; a second impedance module coupled to the third electrode and the fourth electrode, and including a third impedance unit and a fourth impedance unit; an LED unit disposed on a first path coupled to the first impedance module and the second impedance module; a switch coupled to the LED unit for lighting the LED unit when being turned on; a state control module coupled to the switch; a first current sensor coupled between the first impedance unit and the second impedance unit; a first voltage sensor having a first terminal coupled to the first electrode; a second current sensor coupled between the third impedance unit and the fourth impedance unit; a second voltage sensor having a first terminal coupled to the third electrode; and a frequency sensor disposed on a second path connected in parallel to the first path; wherein, when the first current sensor or the second current sensor detects a current flowing between the first electrode and the second electrode or between the third electrode and the fourth electrode, respectively, the state control module turns on the switch; or wherein, when the first voltage sensor or the second voltage sensor detects a voltage difference between the first electrode and the second electrode or between the third electrode and the fourth electrode, respectively, the state control module turns on the switch; or wherein, when the frequency sensor detects a signal with a frequency not lower than 1KHz between the first side and the second side, the state control module turns on the switch. a first side having a first electrode and a second electrode; a second side having a third electrode and a fourth electrode; characterized in further comprising: a first impedance module coupled to the first electrode and the second electrode, and including a first impedance unit and a second impedance unit; a second impedance module coupled to the third electrode and the fourth electrode, and including a third impedance unit and a fourth impedance unit; an LED unit disposed on a first path coupled to the first impedance module and the second impedance module; a switch coupled to the LED unit for lighting the LED unit when being turned on; a state control module coupled to the switch; a first current sensor coupled between the first impedance unit and the second impedance unit; a first voltage sensor having a first terminal coupled to the first electrode; a second current sensor coupled between the third impedance unit and the fourth impedance unit; a second voltage sensor having a first terminal coupled to the third electrode; and a frequency sensor disposed on a second path connected in parallel to the first path; a first impedance module coupled to the first electrode and the second electrode, and including a first impedance unit and a second impedance unit; a second impedance module coupled to the third electrode and the fourth electrode, and including a third impedance unit and a fourth impedance unit; an LED unit disposed on a first path coupled to the first impedance module and the second impedance module; a switch coupled to the LED unit for lighting the LED unit when being turned on; a state control module coupled to the switch; a first current sensor coupled between the first impedance unit and the second impedance unit; a first voltage sensor having a first terminal coupled to the first electrode; a second current sensor coupled between the third impedance unit and the fourth impedance unit; a second voltage sensor having a first terminal coupled to the third electrode; and a frequency sensor disposed on a second path connected in parallel to the first path; wherein, when the first current sensor or the second current sensor detects a current flowing between the first electrode and the second electrode or between the third electrode and the fourth electrode, respectively, the state control module turns on the switch; or wherein, when the first voltage sensor or the second voltage sensor detects a voltage difference between the first electrode and the second electrode or between the third electrode and the fourth electrode, respectively, the state control module turns on the switch; or wherein, when the frequency sensor detects a signal with a frequency not lower than 1KHz between the first side and the second side, the state control module turns on the switch.