mhurhangee/ep-ind-claims huggingface dataset:
A method for producing a fragment library comprising at least two, preferably at least four, length variants of a nucleic acid starting sequence, characterized in that a) each length variant includes a constant central region and in each case a 5' region and a 3' region of variable length, b) each length variant is composed at least of a first partial fragment and a second partial fragment, wherein each first partial fragment includes at least one defined 5' partial region of the constant central region, and each second partial fragment includes at least one defined 3' partial region of the constant central region, and the first and second partial fragments have no frameshift mutations with respect to the nucleic acid starting sequence, c) wherein all first and second partial fragments are joined to one another in one step in such a way that the length variants have all possible combinations of first and second partial fragments, d) and optionally, it is not possible for a combination of first partial fragments with one another or of second partial fragments with one another to take place. a) each length variant includes a constant central region and in each case a 5' region and a 3' region of variable length, b) each length variant is composed at least of a first partial fragment and a second partial fragment, wherein each first partial fragment includes at least one defined 5' partial region of the constant central region, and each second partial fragment includes at least one defined 3' partial region of the constant central region, and the first and second partial fragments have no frameshift mutations with respect to the nucleic acid starting sequence, c) wherein all first and second partial fragments are joined to one another in one step in such a way that the length variants have all possible combinations of first and second partial fragments, d) and optionally, it is not possible for a combination of first partial fragments with one another or of second partial fragments with one another to take place.
Indicator of the opening and/or closing status of a device controlling the flow of a fluid, such as a tap or a pressure reducer for compressed gas, comprising: - a sleeve-shaped support (24, 24') to rotatably engage with a protruding portion of a body of the device and from which an actuating spindle extends along a longitudinal axis of said device; - an indicator sleeve axially sliding along the support (24, 24'); - means for converting a rotation of the spindle into a translation of the indicator sleeve; characterized in that the converting means comprises: - a rotor to be fixed to the spindle and comprising at its periphery at least one track with a curved profile; and - at least one track follower extending radially from the indicator sleeve through a longitudinal slot (24 2, 24 2 ') in the support (24, 24') and engaging with the at least one track. - a sleeve-shaped support (24, 24') to rotatably engage with a protruding portion of a body of the device and from which an actuating spindle extends along a longitudinal axis of said device; - an indicator sleeve axially sliding along the support (24, 24'); - means for converting a rotation of the spindle into a translation of the indicator sleeve; - a rotor to be fixed to the spindle and comprising at its periphery at least one track with a curved profile; and - at least one track follower extending radially from the indicator sleeve through a longitudinal slot (24 2, 24 2 ') in the support (24, 24') and engaging with the at least one track.
Device (1; 1') for adjusting the compression ratio of an internal combustion engine, the said adjusting device (1; 1') comprising: - a connecting rod comprising a connecting rod little end, a connecting rod big end intended to accept a crankshaft of the engine and a connecting rod body connecting the little end to the big end; - a piston comprising a piston pin; - an eccentric comprising - a main shaft installed at the level of the connecting rod little end and comprising an eccentric bore accepting the piston pin; - a lever (43; 53) collaborating with the main shaft so as to cause the main shaft to rotate on itself as a result of the pivoting of the lever (43; 53); - at least one operating element (44; 54; 64) being connected on the one hand to the connecting rod body and on the other hand to the lever (43; 53) so as to cause the lever (43; 53) to pivot; the adjusting device (1; 1') being characterized in that the connecting rod and the operating element (44; 54; 64) are respectively made from materials having different thermal expansion coefficients and having an expansion differential able to cause the lever to pivot. - a connecting rod comprising a connecting rod little end, a connecting rod big end intended to accept a crankshaft of the engine and a connecting rod body connecting the little end to the big end; - a piston comprising a piston pin; - an eccentric comprising - a main shaft installed at the level of the connecting rod little end and comprising an eccentric bore accepting the piston pin; - a lever (43; 53) collaborating with the main shaft so as to cause the main shaft to rotate on itself as a result of the pivoting of the lever (43; 53); - at least one operating element (44; 54; 64) being connected on the one hand to the connecting rod body and on the other hand to the lever (43; 53) so as to cause the lever (43; 53) to pivot; the adjusting device (1; 1') being characterized in that the connecting rod and the operating element (44; 54; 64) are respectively made from materials having different thermal expansion coefficients and having an expansion differential able to cause the lever to pivot.
Railcar adapter, for connecting a railcar body to a bearing, comprising: - a bearing seat adapted to be mounted on the bearing, forming a bearing seat side secured to the bearing, - a top cover adapted to be in contact with the railcar body, forming a frame seat side secured to a bogie frame of the railcar body, and - at least one damping element located between the top cover (21, 31) and the bearing seat, characterized in that the bearing seat is a part of a cylinder having an inner cylindrical surface in radial contact with the bearing and an outer cylindrical surface, and wherein the damping element has an inner cylindrical surface in radial contact with the outer cylindrical surface of the bearing seat, two axial edges (33b, 33c) projecting radially inwards, two lateral edges (33d, 33e) projecting radially inwards and an outer cylindrical surface in radial contact with the top cover. - a bearing seat adapted to be mounted on the bearing, forming a bearing seat side secured to the bearing, - a top cover adapted to be in contact with the railcar body, forming a frame seat side secured to a bogie frame of the railcar body, and - at least one damping element located between the top cover (21, 31) and the bearing seat,
A system that facilitates reconstructing a nuclear medicine image using lesion proxies, comprising: a PET scanner configured to acquire scan data of the patient; a graphical user interface configured to receive parameter information describing one or more lesion proxies for positioning in a nuclear medicine image of a patient; an event simulation module configured to simulate the radioactive decay of the one or more lesion proxies; a reconstruction processor configured to combine simulated lesion proxy data with the acquired scan data, iteratively reconstruct the combined data into a nuclear medicine image, monitor image attributes of said one or more lesion proxies, and adjust reconstruction parameters after a reconstruction iteration as a function of the one or more monitored image attributes; wherein each iteration of the reconstructed nuclear medicine image is displayed on the GUI. a PET scanner configured to acquire scan data of the patient; a graphical user interface configured to receive parameter information describing one or more lesion proxies for positioning in a nuclear medicine image of a patient; an event simulation module configured to simulate the radioactive decay of the one or more lesion proxies; a reconstruction processor configured to combine simulated lesion proxy data with the acquired scan data, iteratively reconstruct the combined data into a nuclear medicine image, monitor image attributes of said one or more lesion proxies, and adjust reconstruction parameters after a reconstruction iteration as a function of the one or more monitored image attributes; wherein each iteration of the reconstructed nuclear medicine image is displayed on the GUI.
A method for high-strength and permanently elastic bonding of at least two surfaces to one another, of which at least one surface is a surface of a permanently elastic plastic, by means of an adhesive comprising a polyurethane component, said method comprising the steps of: a) applying the adhesive to at least a first of the surfaces to be connected, b) ensuring conditions under which at least a first hardening mechanism of the adhesive takes place, said mechanism comprising at least a chemical reaction with the formation of a chemical bond including at least one sulphur atom, c) bringing the first surface provided with the adhesive into contact with the second surface optionally also provided with the adhesive, d) ensuring conditions under which at least a second hardening mechanism of the adhesive takes place, said mechanism comprising at least the formation of crystalline structures from amorphous polymers. a) applying the adhesive to at least a first of the surfaces to be connected, b) ensuring conditions under which at least a first hardening mechanism of the adhesive takes place, said mechanism comprising at least a chemical reaction with the formation of a chemical bond including at least one sulphur atom, c) bringing the first surface provided with the adhesive into contact with the second surface optionally also provided with the adhesive, d) ensuring conditions under which at least a second hardening mechanism of the adhesive takes place, said mechanism comprising at least the formation of crystalline structures from amorphous polymers.
An arrangement for conveying an electronic device in a testing system, the arrangement comprising: a conveyor arrangement; a plate comprising at least one opening for the conveyor arrangement; the arrangement characterized in that it further comprises means for elevating the conveyor arrangement through the at least one opening of the plate, the conveyor arrangement configured to receive and to convey an electronic device when the conveyor arrangement extends through the at least one opening; and means for lowering the conveyor arrangement through the at least one opening of the plate, the plate being configured to receive the electronic device from the conveyor arrangement in response to lowering the conveyor arrangement through the at least one opening, wherein the plate is further configured to move with respect to the conveyor arrangement and to carry the electronic device to a testing area of a testing system. a conveyor arrangement; a plate comprising at least one opening for the conveyor arrangement; the arrangement characterized in that it further comprises means for elevating the conveyor arrangement through the at least one opening of the plate, the conveyor arrangement configured to receive and to convey an electronic device when the conveyor arrangement extends through the at least one opening; and means for lowering the conveyor arrangement through the at least one opening of the plate, the plate being configured to receive the electronic device from the conveyor arrangement in response to lowering the conveyor arrangement through the at least one opening, wherein the plate is further configured to move with respect to the conveyor arrangement and to carry the electronic device to a testing area of a testing system.
Holding device for holding plastic containers and in particular plastic parisons with a holding section which can be introduced into a mouth of the plastic containers, wherein the holding section has at least one first holding element and one second holding element which are movable relative to one another and which in each case have a section which can be applied to an inner wall of the mouth, wherein an expansion body which supports the two holding elements, at least intermittently is disposed between the holding elements,, wherein a replaceable expansion element is disposed on this expansion body, wherein this expansion element is located at least in some sections between the expansion body and the holding elements,, characterized in that the expansion body is movable in a longitudinal direction of the holding device relative to the holding section.
Integrated pump valve unit for providing compressed air to an air bladder of an automotive comfort system within an automotive seat, the integrated pump valve unit comprising: a. a piezoelectrically actuated air pump portion, comprising at least one pump air chamber (12, 14) and at least one pump piezoelectric element for actuating the pump portion; b. a piezoelectrically actuated air valve portion, comprising a valve air chamber and at least one valve piezoelectric element for controlling the opening and closing of an air flow through the valve portion, wherein the valve portion is in fluid connection with the pump portion; and wherein c. the pump portion and the valve portion form a structural unit; characterized in that d. the pump portion comprises a first pump air chamber and a second pump air chamber that are both actuated by the at least one pump piezoelectric element in form of a pump piezoelectric membrane that separates the first pump air chamber and the second pump air chamber. a. a piezoelectrically actuated air pump portion, comprising at least one pump air chamber (12, 14) and at least one pump piezoelectric element for actuating the pump portion; b. a piezoelectrically actuated air valve portion, comprising a valve air chamber and at least one valve piezoelectric element for controlling the opening and closing of an air flow through the valve portion, wherein the valve portion is in fluid connection with the pump portion; and wherein c. the pump portion and the valve portion form a structural unit; characterized in that d. the pump portion comprises a first pump air chamber and a second pump air chamber that are both actuated by the at least one pump piezoelectric element in form of a pump piezoelectric membrane that separates the first pump air chamber and the second pump air chamber.
Arrangement, in particular fuel injection system for high-pressure injection in internal combustion engines, having a fuel distributor and having at least one holder which serves for the fastening of the fuel distributor to a mounting structure, wherein at least one damping composite element is provided, and the damping composite element has at least one metal layer, which is formed at least substantially from a metallic material, and at least one elastically deformable damping layer, characterized in that the holder is formed from a metal sheet and the holder is cohesively connected to the fuel distributor by brazing or welding, and in that the at least one damping composite element is connected to the holder, wherein the damping composite element is connected over approximately its full area to a top side of the holder.
An electrode assembly comprising: a plurality of first and second electrode plates (11, 13) having separators in between, each of the first and second electrode plates having a tab (11a, 13a, 15a, 41a, 51a, 61a) extending therefrom; wherein the tabs of at least one of the first electrode plates or the second electrode plates are wound together to form a wound portion (14, 43, 53, 62) having a plurality of windings; the electrode assembly further comprising an electrode lead (11b, 13b, 15b, 41b, 51b, 61b) connected to an outside surface of the wound portion. a plurality of first and second electrode plates (11, 13) having separators in between, each of the first and second electrode plates having a tab (11a, 13a, 15a, 41a, 51a, 61a) extending therefrom; wherein the tabs of at least one of the first electrode plates or the second electrode plates are wound together to form a wound portion (14, 43, 53, 62) having a plurality of windings; the electrode assembly further comprising an electrode lead (11b, 13b, 15b, 41b, 51b, 61b) connected to an outside surface of the wound portion.
A process to obtain a thermal barrier with transverse microcracks, according to which a ceramic layer of YSZ type is deposited on a bond sublayer via thermal spraying using a plasma arc torch, said bond sublayer itself being deposited on the part to be protected, characterized by the implementation of sintering post-treatment performed by scanning the ceramic layer with the beam of the plasma arc torch, the temperature at the point of impact of the beam on the surface of the ceramic layer during this scanning being between 1300°C and 1700°C.
An optical component, comprising: a hollow-core photonic crystal fiber (101, 910) comprising internal capillaries for guiding radiation and an outer capillary sheathing the internal capillaries; an output end section having a larger inner diameter over at least a portion of said output end section than an inner diameter of the outer capillary along a central portion of the hollow-core photonic crystal fiber (101, 910) prior to the output end section; an input end section; first and second transparent end caps sealing respective ends of the hollow-core photonic crystal fiber (101, 910); a gas medium sealed within a space collectively defined by said hollow-core photonic crystal fiber (101, 910), input and output end sections and end caps; wherein the input end section is comprised between an input end of the hollow-core photonic crystal fiber (101, 910) and the first end cap, and the output end section is comprised between an output end of the hollow-core photonic crystal fiber (101, 910) and the second end cap; characterized in that at least one of the input or output end sections is a tapered end section which tapers outward to define an expanding inner diameter from the hollow-core photonic crystal fiber (101, 910) towards a respective end cap. a hollow-core photonic crystal fiber (101, 910) comprising internal capillaries for guiding radiation and an outer capillary sheathing the internal capillaries; an output end section having a larger inner diameter over at least a portion of said output end section than an inner diameter of the outer capillary along a central portion of the hollow-core photonic crystal fiber (101, 910) prior to the output end section; an input end section; first and second transparent end caps sealing respective ends of the hollow-core photonic crystal fiber (101, 910); a gas medium sealed within a space collectively defined by said hollow-core photonic crystal fiber (101, 910), input and output end sections and end caps; wherein the input end section is comprised between an input end of the hollow-core photonic crystal fiber (101, 910) and the first end cap, and the output end section is comprised between an output end of the hollow-core photonic crystal fiber (101, 910) and the second end cap; characterized in that at least one of the input or output end sections is a tapered end section which tapers outward to define an expanding inner diameter from the hollow-core photonic crystal fiber (101, 910) towards a respective end cap.
Winding device for sails, of the type which can be associated with at least one winder that can be coupled with parts of a boat and that can be actuated at discretion of the yachtsman, comprising at least one stay provided with at least one rigid shaft suitable for transferring the torque provided by the winder, said shaft comprising at least one first shaped end associated with the winder and at least one second shaped end removably coupled to respective locking members, said locking members being at least associated with parts of the mast of a boat in a rotatable manner, and being it foreseen for there to be means for fixing at least one corner of at least one sail associated at least with said shaft, said fixing means being controlled so as to be mobile from a disengagement configuration, in which they are associated in a freely rotating manner at least with said shaft, to an engagement configuration, in which they at least rotate as a unit with said shaft, for the selective and facilitated furling of the sail around at least said shaft pulled in rotation by the winder when said fixing means are in said engagement configuration, at least said second shaped end having a shape corresponding to a respective shaped seat defined in said locking members that are associated in a rotary manner with the mast, for the mutual integral removable coupling, so as to allow the controlled rotation of said shaft by transmission of the torque provided by the winder, said locking members comprising at least one main body defining at least said shaped seat and associated with a head provided with at least one swivel joint for connecting to parts of the boat mast, said main body being associated with at least one tubular stem for housing a segment of said shaft, said stem defining on the outside at least one groove for the removable coupling of said fixing means in said engagement configuration, said fixing means comprising at least one first element substantially in the shape of a ring slidingly associated on at least said shaft and defining at least one protrusion having at least one through hole for connecting a corner of the sail, said first element comprising at least one retractable element that can be fittingly snap-engaged, in a removable manner, inside at least said groove of said stem, so as to achieve said engagement configuration in an automatic manner, and said fixing means comprising at least one substantially ring-shaped second element slidingly associated with at least said shaft and associated in a rotating manner with said first element, said second element defining at least one border having at least one through opening for connecting to at least one halyard of the mast, characterized in that said stem comprises two of said grooves having the ends facing towards said first end of said shaft that are open or suitably filleted, so as to allow the controlled decoupling of two of said respective retractable elements, in said disengagement configuration for said fixing means.