An cartridge assembly (12, 200), comprising: - a cartridge housing configured for receiving a first end of a cartridge (18, 202) that has a chamber containing a medicament and first and second ends, the first end including a seal for sealing the medicament in the chamber, and the second end including a stopper sealingly disposed in the chamber; - an adapter associated with the cartridge housing and configured for coupling the chamber to an injector for transferring the medicament to the injector for loading the injector; and - a cap attached to the cartridge (18, 202) for holding it, - the cap has an interior for receiving the second end of the chamber of cartridge (18, 202) and the stopper; and an end having a post causing movement of the stopper toward the seal when the cap engages the cartridge (18, 202) to thereby eliminate adhesion between the chamber and the stopper; - and - the post is associated with the cartridge housing so as when cartridge (18, 202) is inserted into interior, the post slightly displaces stopper towards seal thus permitting filling of the injector by drawing the medicament from the chamber by vacuum, characterised in that the first end of the cartridge housing has a female thread and the cap has a collar insertable into the first end of the cartridge housing and provided with a male thread that mates with the female thread for connection of the housing with the cap to prevent the post from further displacing the stopper towards the seal. - a cartridge housing configured for receiving a first end of a cartridge (18, 202) that has a chamber containing a medicament and first and second ends, the first end including a seal for sealing the medicament in the chamber, and the second end including a stopper sealingly disposed in the chamber; - an adapter associated with the cartridge housing and configured for coupling the chamber to an injector for transferring the medicament to the injector for loading the injector; and - a cap attached to the cartridge (18, 202) for holding it, - the cap has an interior for receiving the second end of the chamber of cartridge (18, 202) and the stopper; and an end having a post causing movement of the stopper toward the seal when the cap engages the cartridge (18, 202) to thereby eliminate adhesion between the chamber and the stopper; - the cap has an interior for receiving the second end of the chamber of cartridge (18, 202) and the stopper; and an end having a post causing movement of the stopper toward the seal when the cap engages the cartridge (18, 202) to thereby eliminate adhesion between the chamber and the stopper; - and - the post is associated with the cartridge housing so as when cartridge (18, 202) is inserted into interior, the post slightly displaces stopper towards seal thus permitting filling of the injector by drawing the medicament from the chamber by vacuum, characterised in that the first end of the cartridge housing has a female thread and the cap has a collar insertable into the first end of the cartridge housing and provided with a male thread that mates with the female thread for connection of the housing with the cap to prevent the post from further displacing the stopper towards the seal.