mhurhangee/ep-ind-claims huggingface dataset:
A heterologous nucleic acid molecule comprising a nucleotide sequence encoding a polypeptide of interest and a nucleotide sequence encoding the P. pastoris signal amino acid sequence according to SEQ ID NO: 1, the nucleotide sequence encoding said polypeptide of interest being present contiguously (in frame) at and to the 3' end of the nucleotide sequence encoding the amino acid sequence according to SEQ ID NO: 1, such that the nucleotide sequence encoding the amino acid sequence according to SEQ ID NO: 1 and the nucleotide sequence encoding said polypeptide of interest provide a continuous open reading frame for a heterologous polypeptide that consists of the amino acid sequence according to SEQ ID NO: 1 at its N-terminal end and the polypeptide of interest.
A power generation system comprising: a first fluid loop, the first fluid loop comprises: a pump configured to circulate a liquid; a second fluid loop configured to generate power by circulating a supercritical fluid, the second fluid loop comprises: a turbine configured to rotate and power a generator as the supercritical fluid flows through the turbine; and a first rotary liquid piston compressor fluidly coupled to the first fluid loop and the second fluid loop, wherein the first rotary liquid piston compressor is configured to exchange pressure between the liquid circulating in the first fluid loop and the supercritical fluid circulating in the second fluid loop. a first fluid loop, the first fluid loop comprises: a pump configured to circulate a liquid; a second fluid loop configured to generate power by circulating a supercritical fluid, the second fluid loop comprises: a turbine configured to rotate and power a generator as the supercritical fluid flows through the turbine; and a first rotary liquid piston compressor fluidly coupled to the first fluid loop and the second fluid loop, wherein the first rotary liquid piston compressor is configured to exchange pressure between the liquid circulating in the first fluid loop and the supercritical fluid circulating in the second fluid loop.
Angular rate sensor having a first Coriolis element and a second Coriolis element, which are arranged beside each other above a surface of a substrate, excitation means (104, 105, 204, 205) being provided by means of which the Coriolis elements (100, 200) can be excited to oscillate parallel to a first axis, detection means (101, 201) being provided by means of which it is possible to detect a deflection of the Coriolis elements (100, 200) on account of a Coriolis force in a second axis, which is perpendicular to the first axis, the first and the second axis (X, Y) being parallel to the surface of the substrate, wherein the Coriolis elements (100, 200) are arranged in such a way that the oscillations of the first and second Coriolis element (100, 200), excited parallel to the first axis, are effectuated in anti-phase to one another along trajectories that, without the effect of the Coriolis force, are two straight lines which are parallel to one another, the Coriolis elements (100, 200) each having a centre of gravity (110, 210), and the parallel straight lines being perpendicular to a straight line which leads through the two centres of gravity (110, 210), characterized in that, for the detection means, first and second detection elements (140, 240) are provided, which are connected to the Coriolis elements (100, 200) by springs (142, 242), the springs being designed to be weak in the first axis Y and stiff in the second axis x, for the first and second Coriolis element (100, 200), in each case a drive element (102, 202) being provided, which is connected to the respective Coriolis element (100, 200) by means of springs, the springs (103, 203) being designed to be stiff in the first axis Y and weak in the second axis X, the drive elements being connected to the substrate by springs (107, 207), which are designed to be weak in the first axis Y and stiff in the second axis X, and in that the excitation means (104, 204) are connected to the drive elements (102, 202), the detection elements (140, 240) being connected to the substrate by springs (140, 141, 241), which are designed to be stiff in the first direction Y and weak in the second direction X, the drive elements being connected to each other by a coupling spring or the Coriolis elements (100, 200) being connected to each other by coupling springs.
A system comprising a vehicle for collecting a elongated flexible element, such as a hose, that has been laid out on a terrain, and a user control module, the vehicle comprising: - a support frame configured to support a winding assembly for the elongated flexible element; whereby the support frame is configured to be movable across the terrain; and - an actuator configured for actuating the winding assembly for winding the elongated flexible element, thereby pulling the vehicle in a forward movement across the terrain along the elongated flexible element; wherein the vehicle comprises a steering mechanism configured for steering the vehicle along the elongated flexible element, when the vehicle is pulled in the forward movement along the elongated flexible element by the actuator, in response to a force of the elongated flexible element acting on the steering mechanism; wherein the steering mechanism comprises a guiding assembly (322a, 322b) configured for guiding the elongated flexible element to the winding assembly; wherein the vehicle is connected to the user control module, which is configured for controlling the actuator, wherein the user control module is remotely arranged from the vehicle, wherein the user control module is a handheld module, which is connected to the actuator via a wired connection or via a wireless connection. - a support frame configured to support a winding assembly for the elongated flexible element; whereby the support frame is configured to be movable across the terrain; and - an actuator configured for actuating the winding assembly for winding the elongated flexible element, thereby pulling the vehicle in a forward movement across the terrain along the elongated flexible element; wherein the vehicle comprises a steering mechanism configured for steering the vehicle along the elongated flexible element, when the vehicle is pulled in the forward movement along the elongated flexible element by the actuator, in response to a force of the elongated flexible element acting on the steering mechanism; wherein the steering mechanism comprises a guiding assembly (322a, 322b) configured for guiding the elongated flexible element to the winding assembly; wherein the vehicle is connected to the user control module, which is configured for controlling the actuator, wherein the user control module is remotely arranged from the vehicle, wherein the user control module is a handheld module, which is connected to the actuator via a wired connection or via a wireless connection.
An adhesive comprising: (i) a polymer component which contains, in polymerized form, at least 65 wt% of propylene, based on the total weight of the polymer; (ii) at least one nucleator selected from an aromatic tris amide or a multiple amide component; and (iii) a functionalized wax which is a wax grafted with at least one olefinically unsaturated dicarboxylic anhydride of less than 12 carbon atoms and which has a heat of melting greater than 50 J/g. (i) a polymer component which contains, in polymerized form, at least 65 wt% of propylene, based on the total weight of the polymer; (ii) at least one nucleator selected from an aromatic tris amide or a multiple amide component; and (iii) a functionalized wax which is a wax grafted with at least one olefinically unsaturated dicarboxylic anhydride of less than 12 carbon atoms and which has a heat of melting greater than 50 J/g.
Ejector arrangement comprising a housing, at least two ejectors arranged in said housing, each ejector having a motive inlet, a suction inlet, an outlet, and a longitudinal axis, the motive inlets of said ejectors being connected to a common motive line, wherein said suction inlets of said ejectors are connected by means of fluid paths to a common suction line characterized in that each ejector is placed within a cartridge, said cartridge being arranged in said housing, and wherein said cartridge comprises a control valve controlling said motive inlet of said ejector.
A carton loading device comprising a gripper assembly, which comprises at least one gripper arranged to grip and hold a product item from above and to lower the product item from above into a carton, wherein the carton along first parallel sides thereof comprises bottom side flaps and top side flaps and along second parallel sides thereof comprises bottom end flaps and top end flaps, characterized in that the gripper assembly is arranged to move said product item from a pick-up station of the carton loading device to a carton loading station thereof and and to lower said product item into the carton while the carton in the carton loading station is presented in a sleeve state with all flaps unfolded, that the gripper assembly comprises a pinching means arranged to pinch and hold the top side flaps of the carton in the carton loading station, that the gripper assembly is arranged to hold and move the carton and said product item jointly to a carton closing station of the carton loading device, and that the gripper assembly is arranged to release said product item and the carton once the bottom side flaps and the bottom end flaps have been folded in and secured. that the gripper assembly is arranged to move said product item from a pick-up station of the carton loading device to a carton loading station thereof and and to lower said product item into the carton while the carton in the carton loading station is presented in a sleeve state with all flaps unfolded, that the gripper assembly comprises a pinching means arranged to pinch and hold the top side flaps of the carton in the carton loading station, that the gripper assembly is arranged to hold and move the carton and said product item jointly to a carton closing station of the carton loading device, and that the gripper assembly is arranged to release said product item and the carton once the bottom side flaps and the bottom end flaps have been folded in and secured.
A method of controlling a spectral property of a light beam, the method comprising: directing a light beam to a lithography exposure apparatus configured to create a pattern on a wafer; receiving information representative of a spectral property of the light beam; receiving information representative of an optical imaging condition of the lithography exposure apparatus; estimating a characteristic value of the light beam based on the received spectral property information and the received optical imaging condition information; determining whether the estimated light beam characteristic value matches a target light beam characteristic value; and if it is determined that the estimated light beam characteristic value does not match the target light beam characteristic value, adjusting the spectral property of the light beam. directing a light beam to a lithography exposure apparatus configured to create a pattern on a wafer; receiving information representative of a spectral property of the light beam; receiving information representative of an optical imaging condition of the lithography exposure apparatus; estimating a characteristic value of the light beam based on the received spectral property information and the received optical imaging condition information; determining whether the estimated light beam characteristic value matches a target light beam characteristic value; and if it is determined that the estimated light beam characteristic value does not match the target light beam characteristic value, adjusting the spectral property of the light beam.
A wireless communication method for use in a first wireless network node, for determining the connections involved in a Voice over Wireless-Fidelity, VoWifi, call that is performed by means of a user equipment, UE, the method comprising: receiving a local IP address of the UE, at the first wireless network node; determining if the received local IP address of the UE is known to the first wireless network node; and transmitting a message comprising information on the determination to a second wireless network node, wherein the first wireless network node is a Packet Data Network Gateway, PGW, or a Session management function, SMF. receiving a local IP address of the UE, at the first wireless network node; determining if the received local IP address of the UE is known to the first wireless network node; and transmitting a message comprising information on the determination to a second wireless network node, wherein the first wireless network node is a Packet Data Network Gateway, PGW, or a Session management function, SMF.
At least one chemical entity chosen from compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein R 1 is pyridinyl, pyridazinyl, or pyrazolyl, each of which is optionally substituted, or R 1 is wherein A is an optionally substituted heteroaryl group having from 5 to 7 ring atoms including the atoms shared with the 6 membered aromatic ring; R 2 is chosen from 2,3-dimethyl-2H-indazol-6-yl, 1H-indazolyl-6-yl, 1-methyl-1H-indazol-5-yl, 1-methyl-1H-indazol-6-yl, 3,4-dihydro-2H-1,4-benzoxazin-3-one-6-yl, 3,4-dihydro-2H-1,4-benzoxazin-6-yl, 3,4-dihydro-2H-1,4-benzoxazin-7-yl, 1,3-benzoxazol-6-yl, 3-aminoquinolin-6-yl, 2,3-dihydro-1H-indol-6-yl, benzothiazolyl, 2-aminoquinazolin-6-yl, 3,3-dimethylindolin-2-one, 2,3-dihydro-1H-indol-2-one-6-yl, 4-fluoro-1H-indazol-6-yl, 5-fluoro-1H-indazol-6-yl, and 3-amino-1H-indazol-6-yl; R 3 is hydrogen; R 4 is hydrogen; and R 5 is hydrogen. R 1 is pyridinyl, pyridazinyl, or pyrazolyl, each of which is optionally substituted, or R 1 is wherein A is an optionally substituted heteroaryl group having from 5 to 7 ring atoms including the atoms shared with the 6 membered aromatic ring; R 2 is chosen from 2,3-dimethyl-2H-indazol-6-yl, 1H-indazolyl-6-yl, 1-methyl-1H-indazol-5-yl, 1-methyl-1H-indazol-6-yl, 3,4-dihydro-2H-1,4-benzoxazin-3-one-6-yl, 3,4-dihydro-2H-1,4-benzoxazin-6-yl, 3,4-dihydro-2H-1,4-benzoxazin-7-yl, 1,3-benzoxazol-6-yl, 3-aminoquinolin-6-yl, 2,3-dihydro-1H-indol-6-yl, benzothiazolyl, 2-aminoquinazolin-6-yl, 3,3-dimethylindolin-2-one, 2,3-dihydro-1H-indol-2-one-6-yl, 4-fluoro-1H-indazol-6-yl, 5-fluoro-1H-indazol-6-yl, and 3-amino-1H-indazol-6-yl; R 3 is hydrogen; R 4 is hydrogen; and R 5 is hydrogen.
A hemostatic device comprising: a flexible band for enclosure about a wrist at a puncture site, the flexible band including an inner surface; a first balloon coupled to the inner surface of the flexible band; and a second balloon coupled to the inner surface of the flexible band and positioned relative to the first balloon such that a distance between the first balloon and second balloon results in the first balloon being positioned proximal an ulnar artery and the second balloon being positioned proximal a radial artery when the flexible band is enclosed about the wrist; wherein, upon inflation of the first balloon and the second balloon, patent hemostasis is achieved on the ulnar artery and occlusive pressure is generated on the radial artery. a flexible band for enclosure about a wrist at a puncture site, the flexible band including an inner surface; a first balloon coupled to the inner surface of the flexible band; and a second balloon coupled to the inner surface of the flexible band and positioned relative to the first balloon such that a distance between the first balloon and second balloon results in the first balloon being positioned proximal an ulnar artery and the second balloon being positioned proximal a radial artery when the flexible band is enclosed about the wrist; wherein, upon inflation of the first balloon and the second balloon, patent hemostasis is achieved on the ulnar artery and occlusive pressure is generated on the radial artery.
A lighting device, comprising: a lens unit (300, 500) including one or more lenses; and a light source unit which converts light emitted from light emitting units to a surface light source and supplies the light to the lens unit (300, 500), characterised in that the light source unit is integrally connected to the lens unit (300, 500), and the light source unit has flexibility and is curved along the curved surface of the lens unit (300, 500) facing the light source unit. a lens unit (300, 500) including one or more lenses; and a light source unit which converts light emitted from light emitting units to a surface light source and supplies the light to the lens unit (300, 500), characterised in that the light source unit is integrally connected to the lens unit (300, 500), and the light source unit has flexibility and is curved along the curved surface of the lens unit (300, 500) facing the light source unit.
Neutral glass, preferably for use in the pharmaceutical sector, which is free of zirconium and has the following components in % by weight: SiO 2 72 - 82 B 2 O 3 3 - 8 Al 2 O 3 5 - 8 Na 2 O 2.5 - 5.5 K 2 O 3.6 - 8.4 Li 2 O 0 - 0.7 MgO 0 - 0.7 CaO 0 - 0.4 TiO 2 0 - 5 Li 2 O+ Na 2 O+ K 2 O 6.8 - 14.6 K 2 O/Na 2 O ratio 0.7 - 3.4.
A pharmaceutical composition comprising a eutectic composition of two pharmacologically active ingredients for use for delivery to the lung by inhalation, wherein the pharmacologically active ingredients are a long acting β 2 agonist and a long acting muscarinic antagonist.
A subsea process fluid flow measurement system comprising: a venturi flow meter body configured to receive a fluid flow therethrough, the venturi flow meter body having a constricted throat region and a plurality of pressure taps disposed therein; at least one remote seal assembly mounted to a respective pressure tap on the venturi flow meter body, the remote seal assembly comprising: an upper housing having a fluid coupling for coupling the remote seal assembly to a process fluid pressure measurement device; a lower housing coupled to the upper housing and having an interface that is configured to mount to a pressure vessel, the lower housing also having a process fluid inlet; an isolation diaphragm disposed between the upper and lower housings; wherein at least one of the upper housing, lower housing and isolation diaphragm are constructed from a material suitable for immersion in saltwater; a pressure transmitter fluidically coupled (22, 24) to each at least one remote seal assembly; and wherein each remote seal assembly is mounted to the venturi flow meter body by no more than four bolts. a venturi flow meter body configured to receive a fluid flow therethrough, the venturi flow meter body having a constricted throat region and a plurality of pressure taps disposed therein; at least one remote seal assembly mounted to a respective pressure tap on the venturi flow meter body, the remote seal assembly comprising: an upper housing having a fluid coupling for coupling the remote seal assembly to a process fluid pressure measurement device; a lower housing coupled to the upper housing and having an interface that is configured to mount to a pressure vessel, the lower housing also having a process fluid inlet; an isolation diaphragm disposed between the upper and lower housings; wherein at least one of the upper housing, lower housing and isolation diaphragm are constructed from a material suitable for immersion in saltwater; an upper housing having a fluid coupling for coupling the remote seal assembly to a process fluid pressure measurement device; a lower housing coupled to the upper housing and having an interface that is configured to mount to a pressure vessel, the lower housing also having a process fluid inlet; an isolation diaphragm disposed between the upper and lower housings; wherein at least one of the upper housing, lower housing and isolation diaphragm are constructed from a material suitable for immersion in saltwater; a pressure transmitter fluidically coupled (22, 24) to each at least one remote seal assembly; and wherein each remote seal assembly is mounted to the venturi flow meter body by no more than four bolts.
A method of operating a motorized tensioning device in an article of footwear, comprising: receiving from a remote device a user set tension of a tensioning member used to fasten the article of footwear; receiving information related to the tension of the tensioning member from a tension sensor; characterized by operating the motorized tensioning device in a normal operating mode and an active operating mode depending on a user selection; powering down the motorized tensioning device after the user set tension has been achieved in the normal operating mode; continuously sensing a current tension of the tensioning member and adjusting the motorized tensioning device to maintain the target tension in the active operating mode; determining if the current tension is less than the user set tension; automatically controlling the motorized tensioning device to increase the tension of the tensioning member to achieve the user set tension when the current tension is less than the user set tension; and controlling the motorized tensioning device to release tension of the tensioning member when the current tension is greater than the user set tension. receiving from a remote device a user set tension of a tensioning member used to fasten the article of footwear; receiving information related to the tension of the tensioning member from a tension sensor; characterized by operating the motorized tensioning device in a normal operating mode and an active operating mode depending on a user selection; powering down the motorized tensioning device after the user set tension has been achieved in the normal operating mode; continuously sensing a current tension of the tensioning member and adjusting the motorized tensioning device to maintain the target tension in the active operating mode; determining if the current tension is less than the user set tension; automatically controlling the motorized tensioning device to increase the tension of the tensioning member to achieve the user set tension when the current tension is less than the user set tension; and controlling the motorized tensioning device to release tension of the tensioning member when the current tension is greater than the user set tension.
Decorative composite body, comprising a glass body and a plastic partly enclosing said glass body, wherein part of the surface of said glass body is arranged on the outside of said decorative composite body, wherein at least two adjacent glass and plastic areas arranged on the outside of said composite body are simultaneously ground in the composite state, characterized in that areas of said glass body adjacent to said plastic are at least partly mirrored.
An aerosol generating system (400, 401) comprising: a body defining a cavity having a cavity opening; an aerosol-forming substrate disposed in the cavity; a heating element (522, 622) disposed proximate to the cavity opening; a controller configured to detect contact of the aerosol-forming substrate with the heating element (522, 622); and a mechanical advancement mechanism configured to advance the aerosol-forming substrate towards the heating element (522, 622). a body defining a cavity having a cavity opening; an aerosol-forming substrate disposed in the cavity; a heating element (522, 622) disposed proximate to the cavity opening; a controller configured to detect contact of the aerosol-forming substrate with the heating element (522, 622); and a mechanical advancement mechanism configured to advance the aerosol-forming substrate towards the heating element (522, 622).