mhurhangee/ep-ind-claims huggingface dataset:
A method for preparing an anti-procalcitonin antibody, comprising the following steps of: mutating the amino acid residues of procalcitonin, to obtain a nucleotide sequence corresponding to the sequence of the mutated amino acid residues; inserting the nucleotide sequence into a prokaryotic expression vector, and carrying out an induction expression and protein purification; and immunizing an animal with the purified protein as immunogen, fusing the splenocytes from the animal with mouse myeloma cells to prepare hybridoma cells, and screening to obtain the hybridoma cells that can stably secrete an anti-procalcitonin antibody, and obtain the corresponding monoclonal antibody; wherein the mutated procalcitonin amino acid sequences are SEQ ID NOs: 2-4; and wherein the anti-procalcitonin antibody is obtained from a hybridoma cell line with an accession number of CGMCC No. 10417. mutating the amino acid residues of procalcitonin, to obtain a nucleotide sequence corresponding to the sequence of the mutated amino acid residues; inserting the nucleotide sequence into a prokaryotic expression vector, and carrying out an induction expression and protein purification; and immunizing an animal with the purified protein as immunogen, fusing the splenocytes from the animal with mouse myeloma cells to prepare hybridoma cells, and screening to obtain the hybridoma cells that can stably secrete an anti-procalcitonin antibody, and obtain the corresponding monoclonal antibody; wherein the mutated procalcitonin amino acid sequences are SEQ ID NOs: 2-4; and wherein the anti-procalcitonin antibody is obtained from a hybridoma cell line with an accession number of CGMCC No. 10417.
A stencil device (100, 150) for simultaneous stencil printing of brazing material onto elevations, areas surrounding port openings, and a circumferential skirt of a heat exchanger plate characterized in that the stencil device comprises an upper stencil having openings (120, 130) for applying brazing material to elevations and areas surrounding port openings of the heat exchanger plate and a lower stencil printing stencil having a large opening for receiving a heat exchanger plate and contacting an outer perimeter of the circumferential skirt of the heat exchanger plate, wherein an inner surface of the large opening comprises brazing material exits for applying brazing material to the circumferential skirts.
A method for detecting a first cellular target nucleic acid sequence in situ in a tissue sample comprising: contacting said tissue sample with a first nucleic acid molecule comprising a target probe portion comprising a nucleic acid sequence complementary to said first cellular target nucleic acid sequence and a detection target portion comprising a plurality of first detection target sequences that are complementary to at least one detection probe nucleic acid sequence and non-complementary to said target nucleic acid sequence, under conditions where said target probe portion of said first nucleic acid molecule hybridizes directly to said cellular target nucleic acid sequence; contacting said first nucleic acid molecule with a plurality of second nucleic acid molecules each comprising a detection probe portion complementary to said detection target sequences of said first nucleic acid molecule and a detectable moiety portion comprising at least one first detectable moiety either 5' or 3' to said detection probe portion, wherein said at least one first detectable moiety is incorporated into the nucleic acid molecule, under conditions such that said detection probe portion of said second nucleic acid molecule hybridizes to said first detection target sequences of said first nucleic acid molecule; and detecting said at least one first detectable moiety. contacting said tissue sample with a first nucleic acid molecule comprising a target probe portion comprising a nucleic acid sequence complementary to said first cellular target nucleic acid sequence and a detection target portion comprising a plurality of first detection target sequences that are complementary to at least one detection probe nucleic acid sequence and non-complementary to said target nucleic acid sequence, under conditions where said target probe portion of said first nucleic acid molecule hybridizes directly to said cellular target nucleic acid sequence; contacting said first nucleic acid molecule with a plurality of second nucleic acid molecules each comprising a detection probe portion complementary to said detection target sequences of said first nucleic acid molecule and a detectable moiety portion comprising at least one first detectable moiety either 5' or 3' to said detection probe portion, wherein said at least one first detectable moiety is incorporated into the nucleic acid molecule, under conditions such that said detection probe portion of said second nucleic acid molecule hybridizes to said first detection target sequences of said first nucleic acid molecule; and detecting said at least one first detectable moiety.
A method for determination of a location of an attached User Equipment in a tunnelled IP network by means of a second source address, said tunnelled IP network comprising a tunnel termination function, TTF, whereby the User Equipment location has been determined and maintained in a Location Function, LF, and the method comprises the steps of: - Maintaining in the Location Function a correlation between the User Equipment and a first source address of the User Equipment in a first IP network through which an IP tunnel has been established into a second IP network thereby constituting the tunnelled IP network (step 60); - Updating by means of the tunnel termination function the Location Function with the second source address of the User Equipment in the second IP network in context of the first source address, whereby the Location Function is adapted to correlate the first source address with the second source address (step 61); and - Querying the Location Function for the User Equipment location and retrieving the User Equipment location by using the second source address as a key (steps 62 - 64). - Maintaining in the Location Function a correlation between the User Equipment and a first source address of the User Equipment in a first IP network through which an IP tunnel has been established into a second IP network thereby constituting the tunnelled IP network (step 60); - Updating by means of the tunnel termination function the Location Function with the second source address of the User Equipment in the second IP network in context of the first source address, whereby the Location Function is adapted to correlate the first source address with the second source address (step 61); and - Querying the Location Function for the User Equipment location and retrieving the User Equipment location by using the second source address as a key (steps 62 - 64).
A rocking chair for children, characterized by comprising a seat body, a supporting frame and a seat body limiting mechanism, wherein the supporting frame comprises a driving mechanism, the driving mechanism comprises a driving motor, a driving motor power output part and a rotating shaft, the seat body is used for carrying a child, there is only one rotating shaft providing a sole support for the seat body, one end of the rotating shaft pivots at the supporting frame and is fixedly connected with the driving motor power output part, another end of the rotating shaft pivots at the seat body, and a vertical line from ground to a pivot point between the rotating shaft and the supporting frame deviates from a vertical line from the ground to a pivot point between the rotating shaft and the seat body; the seat body limiting mechanism comprises a limiting piece and a limiting matching piece matched with the limiting piece, the limiting piece is movably connected with the limiting matching piece, when the rotating shaft rotates, the rotating shaft is rotated relative to the seat body, and the seat body limiting mechanism limits an included angle between the seat body and the rotating shaft to be kept at pre-set angles; wherein the limiting piece is connected with the seat body, and the limiting matching piece is arranged on the supporting frame; or the limiting piece is connected to the supporting frame, and the limiting matching piece is arranged on the seat body.
A multilayer motor vehicle pipe, in particular fuel pipe for motor vehicles, wherein the pipe has at least two layers, preferably at least three layers (4, 5, 6) made of plastic, wherein at least one surface of at least one layer connected with an additional layer has a profiled design, wherein the profiling has maximums and minimums, characterized in that the profiling of the at least one profiled surface has a wavy or wavelike cross section, wherein the difference in height Δh between the maximums and the minimums directly adjacent to the maximums lies between 1 and 100 μm, primarily between 1 and 50 μm, and preferably between 1 and 25 μm, and wherein the distances a between the maximums and the minimums directly adjacent to the maximums of a profiled surface measure 1 to 100 μm. characterized in that the profiling of the at least one profiled surface has a wavy or wavelike cross section, wherein the difference in height Δh between the maximums and the minimums directly adjacent to the maximums lies between 1 and 100 μm, primarily between 1 and 50 μm, and preferably between 1 and 25 μm, and wherein the distances a between the maximums and the minimums directly adjacent to the maximums of a profiled surface measure 1 to 100 μm.
Production machine system, comprising: - a production machine having at least one first position-controlled drive by means of which at least one first machine element (A1 - A5, B) can be adjusted relative to a further machine element (A1 - A5, B) with respect to an axis (R1 - R5, L1), - a control facility for controlling the position-controlled drive so as to move the first machine element (A1 - A5, B) relative to the further machine element (A1 - A5, B), - a model of the first machine element (A1 - A5, B) which is stored in the control facility and which comprises at least one model parameter of the first machine element (A1 - A5, B), - measuring equipment (4A, 4B, 4C) for determining a path (K1 - K5) which describes a specific point (P, TCP) that is assigned to the first machine element (A1 - A5, B) during a movement of the first machine element (A1 - A5, B), - analysis means for analysing the specific path (K1 - K5), - correction means for correcting the model parameter based on the analysis result, wherein the production machine comprises multiple axes (R1 - R5, L1) and drives, which are separated from each other in each case by at least one machine element (A1 - A5, B), and wherein the drives and machine elements (A1 - A5, B) form a kinematic chain, characterised in that in order to determine the respective path (K1 - K5), multiple, in particular all axes (R1 - R5, L1) are moved one after the other starting from a base along the kinematic chain. - a production machine having at least one first position-controlled drive by means of which at least one first machine element (A1 - A5, B) can be adjusted relative to a further machine element (A1 - A5, B) with respect to an axis (R1 - R5, L1), - a control facility for controlling the position-controlled drive so as to move the first machine element (A1 - A5, B) relative to the further machine element (A1 - A5, B), - a model of the first machine element (A1 - A5, B) which is stored in the control facility and which comprises at least one model parameter of the first machine element (A1 - A5, B), - measuring equipment (4A, 4B, 4C) for determining a path (K1 - K5) which describes a specific point (P, TCP) that is assigned to the first machine element (A1 - A5, B) during a movement of the first machine element (A1 - A5, B), - analysis means for analysing the specific path (K1 - K5), - correction means for correcting the model parameter based on the analysis result, wherein the production machine comprises multiple axes (R1 - R5, L1) and drives, which are separated from each other in each case by at least one machine element (A1 - A5, B), and wherein the drives and machine elements (A1 - A5, B) form a kinematic chain, characterised in that in order to determine the respective path (K1 - K5), multiple, in particular all axes (R1 - R5, L1) are moved one after the other starting from a base along the kinematic chain.
A cable transition for connecting several signal lines incoming at a first signal-processing unit, which is arranged on a first carrier, with several signal lines outgoing from a second signal-processing unit, which is arranged on a second carrier which is swivelable against the first carrier, comprising a connecting cable extending between the two signal-processing units (2, 4), wherein the first signal-processing unit comprises a first multichannel signal converter which converts measuring, monitoring and/or control signals incoming on the incoming signal lines into a bunched transmission signal which can be transmitted through the connecting cable and whose signal output is in connection with one end of the connecting cable, and wherein the second signal-processing unit comprises a second multichannel signal converter which serves as a signal reconverter and which is in connection with the other end of the connecting cable and supplies on its outputs signals corresponding to the original measuring, monitoring and/or control signals, characterized in that at least one signal-processing unit (2, 4) comprises at least one connecting element for signal-side connection of the processor unit and/or the signal converter with a processor unit and/or a signal converter of a third signal-processing unit, and in that at least part of the signal-processing units (2, 4, 30) each comprise a transmitting and receiving unit (16, 20, 38) for wireless transmission of data, and in that at least one signal-processing unit (2, 4, 30) comprises a processor unit (12, 22, 34) which is connected on the signal side with the respective transmitting and receiving unit (16, 20, 38) and the signal converter (14, 18, 36).
An isolated bacteria selected from a group consisting of Bacillus amyloliquefaciens strain AP-136 (Accession No. NRRL B-50614), Bacillus amyloliquefaciens strain AP-188 (Accession No. NRRL B-50615), Bacillus amyloliquefaciens strain AP-218 (Accession No. NRRL B-50618), Bacillus amyloliquefaciens strain AP-219 (Accession No. NRRL B-50619), and Bacillus amyloliquefaciens strain AP-295 (Accession No. NRRL B-50620), Bacillus mojavensis strain AP-209 (Accession No. NRRL B-50616), Bacillus solisalsi strain AP-217 (Accession No. NRRL B-50617), Bacillus simplex strain ABU 288 (Accession No. NRRL B-50340), Bacillus subtilis strain MBI 600 (Accession No. B-50595).
A parking assist method used in a parking assist apparatus comprising a control device, the control device being configured to: execute a detection process for a parking space that satisfies a predefined parking condition wherein the predefined parking condition is defined by predetermined criteria to be satisfied by a parking space to be detected; and when a parking space satisfying the parking condition is detected, present the parking space as a first parking space (Mr); characterized in that the control device is further configured to determine a target parking space input by an operator (106: YES); determine whether the target parking space input by the operator is the first parking space presented and, if this is not the case (S1: YES), change the predefined parking condition by relaxing said predetermined criteria and re-execute the detection process in order to detect the target parking space satisfying the changed parking condition as first parking space. execute a detection process for a parking space that satisfies a predefined parking condition wherein the predefined parking condition is defined by predetermined criteria to be satisfied by a parking space to be detected; and when a parking space satisfying the parking condition is detected, present the parking space as a first parking space (Mr); characterized in that the control device is further configured to determine a target parking space input by an operator (106: YES); determine whether the target parking space input by the operator is the first parking space presented and, if this is not the case (S1: YES), change the predefined parking condition by relaxing said predetermined criteria and re-execute the detection process in order to detect the target parking space satisfying the changed parking condition as first parking space.
A reload for a surgical stapler configured to be releasably coupled to an adapter, said reload comprising: a proximal body portion defining a longitudinal axis and including a housing, a drive member movably supported within the housing between a retracted position and an advanced position, a first articulation link and, a second articulation link; a tool assembly defining a longitudinal axis and being pivotably supported on a distal end of the proximal body portion, the tool assembly including a first jaw and a second jaw, the first jaw being pivotable in relation to the second jaw between a spaced position and a clamped position; a mounting assembly secured to a proximal portion of the tool assembly, the mounting assembly including a pivot member defining a pivot axis between the tool assembly and the distal end of the proximal body portion, the first articulation link being connected to the mounting assembly on one side of the pivot axis and the second articulation link being connected to the mounting assembly on an opposite side of the pivot axis; wherein the first and second articulation links (28,30) are axially movable within the housing to pivot the tool assembly about the pivot axis from a non-articulated position to a plurality of articulated positions; a stabilization system including a slide member slidably positioned on the housing of the proximal body portion and a biasing member, the slide member being engaged with the first and second articulation links (28,30), and the biasing member being positioned to urge the slide member in a direction to urge the tool assembly towards the non-articulated position. a proximal body portion defining a longitudinal axis and including a housing, a drive member movably supported within the housing between a retracted position and an advanced position, a first articulation link and, a second articulation link; a tool assembly defining a longitudinal axis and being pivotably supported on a distal end of the proximal body portion, the tool assembly including a first jaw and a second jaw, the first jaw being pivotable in relation to the second jaw between a spaced position and a clamped position; a mounting assembly secured to a proximal portion of the tool assembly, the mounting assembly including a pivot member defining a pivot axis between the tool assembly and the distal end of the proximal body portion, the first articulation link being connected to the mounting assembly on one side of the pivot axis and the second articulation link being connected to the mounting assembly on an opposite side of the pivot axis; wherein the first and second articulation links (28,30) are axially movable within the housing to pivot the tool assembly about the pivot axis from a non-articulated position to a plurality of articulated positions; a stabilization system including a slide member slidably positioned on the housing of the proximal body portion and a biasing member, the slide member being engaged with the first and second articulation links (28,30), and the biasing member being positioned to urge the slide member in a direction to urge the tool assembly towards the non-articulated position.
A tablet comprising a first region and a second region, wherein: (i) said first region and said second region each comprise at least 10%, by volume, of said tablet; (ii) said first region comprises a pharmaceutically active agent and the composition of said first region is different from the composition of said second region; (iii) said first region has a density less than 0.8 g/cc; and (iv) said first region disintegrates in the mouth when placed on the tongue in less than 30 seconds; wherein the shape of said tablet comprises two opposing major faces separated by a side wall, and the interface between said first region and said second region is along both of the major faces of said tablet such that the interface extends through the tablet and both major faces of said tablet. (i) said first region and said second region each comprise at least 10%, by volume, of said tablet; (ii) said first region comprises a pharmaceutically active agent and the composition of said first region is different from the composition of said second region; (iii) said first region has a density less than 0.8 g/cc; and (iv) said first region disintegrates in the mouth when placed on the tongue in less than 30 seconds; wherein the shape of said tablet comprises two opposing major faces separated by a side wall, and the interface between said first region and said second region is along both of the major faces of said tablet such that the interface extends through the tablet and both major faces of said tablet.
Fouling reducing device for the tubes of a tubular heat exchanger of the type that comprises at least one turbulence generating element lodged inside one of the tubes of said exchanger and brought, during its use, in contact with an environment that contains hydrocarbons, in particular crude oil, characterized in that said element, meant to come in contact with the hydrocarbons is made of a metallic alloy whose nickel content is greater than 50% by weight and furthermore includes at least one metal chosen from the group consisting of chrome and molybdenum to improve its resistance to corrosion, said alloy being constituted of the following materials (in % by weight): - nickel: 64.9, - chrome: 22.16, - molybdenum: 8.75, - niobium: 3.62, - iron: 0.19, - titanium: 0.18, - aluminum: 0.089, - silicon: 0.057, - magnesium: 0.022, - carbon: 0.012, - cupper:0.010, - cobalt: 0.005, - phosphorous: 0.003, - sulfur: 0.002. - nickel: 64.9, - chrome: 22.16, - molybdenum: 8.75, - niobium: 3.62, - iron: 0.19, - titanium: 0.18, - aluminum: 0.089, - silicon: 0.057, - magnesium: 0.022, - carbon: 0.012, - cupper:0.010, - cobalt: 0.005, - phosphorous: 0.003, - sulfur: 0.002.