Method for manufacturing a silk-based fabric for use as a covering in a passenger compartment of a motor vehicle, in particular for seats, comprising the steps of: manufacturing a twisted silk yarn having predetermined characteristics, and manufacturing an orthogonal woven fabric with warp and weft threads manufactured using said twisted yarn; the method being characterized in that * the manufacture of said twisted yarn comprises the steps of: - providing first and second single-thread yarns of raw silk having a metric count (Nm) equal to or greater than 80 and a Z-type twist equal to or greater than 600 turns/linear metre; - doubling and twining said first and second yarns, one with the other, so as to provide doubled and twined yarns having an S-type twist equal to or greater than 350 turns/linear metre; - skein-dyeing said doubled and twined yarns and subsequently winding-off said skein; and - preparing said twisted yarn by plying and twisting a plurality of said doubled and twined yarns - preferably three of said doubled and twined yarns - with an S-type twist comprised between 300 and 500 turns/linear metre, and in that * the manufacture of said fabric comprises the steps of: - preparing a warp with said twisted yarn, with a thread density of more than 20 threads/centimetre, without applying to the warp threads any oils or waxes, and - weaving the warp with weft threads, with a density greater than 18 weft threads/centimetre, without applying to the weft threads any oils or waxes. manufacturing a twisted silk yarn having predetermined characteristics, and manufacturing an orthogonal woven fabric with warp and weft threads manufactured using said twisted yarn; the method being characterized in that * the manufacture of said twisted yarn comprises the steps of: - providing first and second single-thread yarns of raw silk having a metric count (Nm) equal to or greater than 80 and a Z-type twist equal to or greater than 600 turns/linear metre; - doubling and twining said first and second yarns, one with the other, so as to provide doubled and twined yarns having an S-type twist equal to or greater than 350 turns/linear metre; - skein-dyeing said doubled and twined yarns and subsequently winding-off said skein; and - preparing said twisted yarn by plying and twisting a plurality of said doubled and twined yarns - preferably three of said doubled and twined yarns - with an S-type twist comprised between 300 and 500 turns/linear metre, and in that * the manufacture of said fabric comprises the steps of: - preparing a warp with said twisted yarn, with a thread density of more than 20 threads/centimetre, without applying to the warp threads any oils or waxes, and - weaving the warp with weft threads, with a density greater than 18 weft threads/centimetre, without applying to the weft threads any oils or waxes. * the manufacture of said twisted yarn comprises the steps of: - providing first and second single-thread yarns of raw silk having a metric count (Nm) equal to or greater than 80 and a Z-type twist equal to or greater than 600 turns/linear metre; - doubling and twining said first and second yarns, one with the other, so as to provide doubled and twined yarns having an S-type twist equal to or greater than 350 turns/linear metre; - skein-dyeing said doubled and twined yarns and subsequently winding-off said skein; and - preparing said twisted yarn by plying and twisting a plurality of said doubled and twined yarns - preferably three of said doubled and twined yarns - with an S-type twist comprised between 300 and 500 turns/linear metre, and in that - providing first and second single-thread yarns of raw silk having a metric count (Nm) equal to or greater than 80 and a Z-type twist equal to or greater than 600 turns/linear metre; - doubling and twining said first and second yarns, one with the other, so as to provide doubled and twined yarns having an S-type twist equal to or greater than 350 turns/linear metre; - skein-dyeing said doubled and twined yarns and subsequently winding-off said skein; and - preparing said twisted yarn by plying and twisting a plurality of said doubled and twined yarns - preferably three of said doubled and twined yarns - with an S-type twist comprised between 300 and 500 turns/linear metre, * the manufacture of said fabric comprises the steps of: - preparing a warp with said twisted yarn, with a thread density of more than 20 threads/centimetre, without applying to the warp threads any oils or waxes, and - weaving the warp with weft threads, with a density greater than 18 weft threads/centimetre, without applying to the weft threads any oils or waxes. - preparing a warp with said twisted yarn, with a thread density of more than 20 threads/centimetre, without applying to the warp threads any oils or waxes, and - weaving the warp with weft threads, with a density greater than 18 weft threads/centimetre, without applying to the weft threads any oils or waxes.