mhurhangee/ep-ind-claims huggingface dataset:
A compound represented by the following formula: or its pharmaceutically acceptable salt, wherein ring A is substituted or unsubstituted heterocycle; R 1 is alkyl; or R 1 may be taken together with atom(s) constituting the ring A to form substituted or unsubstituted heterocycle; R 2 is alkyloxy, or substituted or unsubstituted cycloalkyloxy; R 3 is selected from the following groups: wherein the above groups may be substituted with same or different 1 to 4 substituent consisting of alkyl, alkoxy, halogen, hydroxy, hydroxyalkyl, alkoxyalkyl, haloalkyl, oxo, amino, mono or di alkylamino, aminoalkyl, mono or di alkylaminoalkyl and cyano; and R 6 is alkyl. ring A is substituted or unsubstituted heterocycle; R 1 is alkyl; or R 1 may be taken together with atom(s) constituting the ring A to form substituted or unsubstituted heterocycle; R 2 is alkyloxy, or substituted or unsubstituted cycloalkyloxy; R 3 is selected from the following groups: wherein the above groups may be substituted with same or different 1 to 4 substituent consisting of alkyl, alkoxy, halogen, hydroxy, hydroxyalkyl, alkoxyalkyl, haloalkyl, oxo, amino, mono or di alkylamino, aminoalkyl, mono or di alkylaminoalkyl and cyano; and R 6 is alkyl.
A seal assembly (178, 278, 478) for a gas turbine engine comprising: a seal (169, 269, 469) including a seal body (169A, 469A) extending circumferentially between opposed mate faces, the seal body (169A, 469A) having a seal face that bounds a gas path and an opposed impingement face; a seal carrier (182, 282, 482) extending along the impingement face; and a seal member (184, 284, 484) trapped between the seal carrier (182, 282, 482) and the impingement face such that the seal member (184, 284, 484) is circumferentially aligned with one of the mate faces; characterised in that: the seal carrier (182, 282, 482) includes a carrier body, defining a recess, the carrier body is seated against the impingement face to define an impingement cavity along the recess, and the carrier body defines a plurality of impingement apertures along the recess, each of the impingement apertures having a passage axis that intersects the impingement face, wherein the seal carrier (182, 282, 482) is an impingement plate and the seal member (184, 284, 484) is a feather seal, and the seal carrier (182, 282, 482) defines an elongated channel (182E, 482E) dimensioned to receive a main body (184A, 284A, 484A) of the seal member (184, 284, 484) such that the main body (184A, 284A, 484A) bounds the impingement cavity. a seal (169, 269, 469) including a seal body (169A, 469A) extending circumferentially between opposed mate faces, the seal body (169A, 469A) having a seal face that bounds a gas path and an opposed impingement face; a seal carrier (182, 282, 482) extending along the impingement face; and a seal member (184, 284, 484) trapped between the seal carrier (182, 282, 482) and the impingement face such that the seal member (184, 284, 484) is circumferentially aligned with one of the mate faces; characterised in that: the seal carrier (182, 282, 482) includes a carrier body, defining a recess, the carrier body is seated against the impingement face to define an impingement cavity along the recess, and the carrier body defines a plurality of impingement apertures along the recess, each of the impingement apertures having a passage axis that intersects the impingement face, wherein the seal carrier (182, 282, 482) is an impingement plate and the seal member (184, 284, 484) is a feather seal, and the seal carrier (182, 282, 482) defines an elongated channel (182E, 482E) dimensioned to receive a main body (184A, 284A, 484A) of the seal member (184, 284, 484) such that the main body (184A, 284A, 484A) bounds the impingement cavity.
A location relationship obtaining method, comprising: when moving, detecting, by a collection terminal, wireless signals sent by ambient searched terminals; obtaining, by the collection terminal, at least two reference location points according to the detected wireless signals sent by the ambient searched terminals, wherein each reference location point is a location point for obtaining, by the collection terminal, a wireless signal that has greatest strength in multiple wireless signals sent by a corresponding searched terminal; and using, by the collection terminal, either of the at least two reference location points as a benchmark location point, and obtaining, by the collection terminal, a reference location relationship between each of the other reference location points and the benchmark location point, wherein the reference location relationship comprises a distance between each of the other reference location points and the benchmark location point and an angle of orientation of each of the other reference location points relative to the benchmark location point, and the reference location relationship is used to indicate a location relationship between a searched terminal corresponding to each of the other reference location points and a searched terminal corresponding to the benchmark location point. when moving, detecting, by a collection terminal, wireless signals sent by ambient searched terminals; obtaining, by the collection terminal, at least two reference location points according to the detected wireless signals sent by the ambient searched terminals, wherein each reference location point is a location point for obtaining, by the collection terminal, a wireless signal that has greatest strength in multiple wireless signals sent by a corresponding searched terminal; and using, by the collection terminal, either of the at least two reference location points as a benchmark location point, and obtaining, by the collection terminal, a reference location relationship between each of the other reference location points and the benchmark location point, wherein the reference location relationship comprises a distance between each of the other reference location points and the benchmark location point and an angle of orientation of each of the other reference location points relative to the benchmark location point, and the reference location relationship is used to indicate a location relationship between a searched terminal corresponding to each of the other reference location points and a searched terminal corresponding to the benchmark location point.
A vision measuring device, comprising: an imaging device which images a measurement target and transfers image information representing an image of the measurement target; a position control device which controls an in-focus position of the imaging device and outputs the in-focus position as position information representing a position in an in-focus axis direction; and a vision measuring system which performs vision measurement on the measurement target based on the image information and the position information, characterized in that: the imaging device adds serial number information; the position control device acquires the position information in response to a trigger signal which is output from one of the imaging device and the position control device to the other of them at a certain timing of an imaging period during which the imaging device images the measurement target and retains the position information in association with the serial number information; and the vision measuring system calculates position information representing a position of the image information in the in-focus axis direction based on the image information with the serial number information transferred from the imaging device and the position information in association with the serial number information output from the position control device, and performs auto-focusing control by using the calculated position information. an imaging device which images a measurement target and transfers image information representing an image of the measurement target; a position control device which controls an in-focus position of the imaging device and outputs the in-focus position as position information representing a position in an in-focus axis direction; and a vision measuring system which performs vision measurement on the measurement target based on the image information and the position information, the imaging device adds serial number information; the position control device acquires the position information in response to a trigger signal which is output from one of the imaging device and the position control device to the other of them at a certain timing of an imaging period during which the imaging device images the measurement target and retains the position information in association with the serial number information; and the vision measuring system calculates position information representing a position of the image information in the in-focus axis direction based on the image information with the serial number information transferred from the imaging device and the position information in association with the serial number information output from the position control device, and performs auto-focusing control by using the calculated position information.
A tile for a covering, said tile having a Young's modulus E' tile and comprising, joined to one of its faces, a layer of damping material conferring vibratory energy dissipation properties on the tile, characterized in that said layer of damping material has, at 20°C, between 10 Hz and 5000 Hz, a loss factor tanδ at least equal to 0.08, preferably higher than 0.3, and a dynamic Young's modulus E' material of between 5×10 6 Pa and 10 9 Pa, and in that the ratio E' material /E' tile is lower than 0.09.
Suspension of a tool on a vehicle where the tool is to adapt to changing surface, where the tool is attached to the vehicle by an arm, and where the arm at a first end is connected to the vehicle and the tool is attached to a second end of the arm, and where a first pivot joint is positioned between the vehicle and the tool allowing a rotation around a first pivot axis of the tool relative to the vehicle in a direction of up and down relative to the terrain, where the suspension comprises balancing system where the balancing system comprises a first part attached to the vehicle and to a position at the arm and where a first adjustable actuating member acts with a first adjustable force on the arm to give an upward rotation of the tool relative to the vehicle around the first pivot joint, characterized in that a second pivot joint is positioned at a position between the first pivot joint and the tool allowing a rotation of the tool relative to the section of the arm between the first and second pivot joints in a direction of up and down relative to the terrain.
A laser welding method comprising: a first step for forming a weld bead (60, 61, 601, 602, 603, 611, 612, 613) by irradiating an object to be welded with a laser beam along a first helical trajectory around a first center of rotation moving in a welding direction; characterized by a second step for irradiating the object to be welded with a laser beam along a second helical trajectory around a second center of rotation moving in the welding direction, wherein a diameter of rotation of the laser beam in the first step is larger than a diameter of rotation of the laser beam in the second step. a first step for forming a weld bead (60, 61, 601, 602, 603, 611, 612, 613) by irradiating an object to be welded with a laser beam along a first helical trajectory around a first center of rotation moving in a welding direction; characterized by a second step for irradiating the object to be welded with a laser beam along a second helical trajectory around a second center of rotation moving in the welding direction, wherein a diameter of rotation of the laser beam in the first step is larger than a diameter of rotation of the laser beam in the second step.
Method for compensating for a loss of traction of a rail vehicle in a track curve, characterized in that comparatively unfavourable friction conditions between a rail and at least one driven track wheel (210, 210) of the rail vehicle are changed into comparatively favourable friction conditions by actively steering the track wheel (210, 210) on the rail.
The pyrimidylaminobenzamide derivative named 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide of formula: or a N-oxide or a pharmaceutially acceptable salt thereof, for use in a method for the treatment of a TEL-PDGFRβ-induced myeloproliferative disease.
An isolated polynucleotide which comprises: a nucleotide sequence having at least 80% identity to the nucleotide sequence of SEQ ID NO: 1; and wherein said polynucleotide encodes a lipolytic enzyme and wherein said lipolytic enzyme comprises when compared to the protein of SEQ ID NO: 2 five extra glycosylation sites by modifying, when compared to SEQ ID NO:2, A70 to S, K98 to N, R158 to N and R159 to K, H318 to N and P320 to S and I361 to T or wherein said lipolytic enzyme comprises when compared to SEQ ID NO: 2 an increase in the number of polar residues of at least 16 and an increase in the number of charged amino acids of at least 11, and wherein said lipolytic enzyme has improved solubility in the supernatant after secretion from a host cell when compared to the protein of SEQ ID NO:2, and wherein said lipolytic enzyme has a higher specificity towards the release of C4-C10 free fatty acids, when compared to the release of C12-C18 free fatty acids. a nucleotide sequence having at least 80% identity to the nucleotide sequence of SEQ ID NO: 1; and wherein said lipolytic enzyme comprises when compared to the protein of SEQ ID NO: 2 five extra glycosylation sites by modifying, when compared to SEQ ID NO:2, A70 to S, K98 to N, R158 to N and R159 to K, H318 to N and P320 to S and I361 to T or wherein said lipolytic enzyme comprises when compared to SEQ ID NO: 2 an increase in the number of polar residues of at least 16 and an increase in the number of charged amino acids of at least 11, and wherein said lipolytic enzyme has improved solubility in the supernatant after secretion from a host cell when compared to the protein of SEQ ID NO:2, and wherein said lipolytic enzyme has a higher specificity towards the release of C4-C10 free fatty acids, when compared to the release of C12-C18 free fatty acids.
A vane adapted for use with a rotor said vane comprising: a plate; characterised by a slot extending transversely to one edge of said plate, said slot being defined by first and second oppositely disposed edges and a third edge oriented transversely to said first and second edges; an insert removably mounted within said slot said insert comprising: a base engageable with said third edge of said slot; a first leg projecting transversely to said base and engageable with said first edge of said slot; a second leg projecting transversely to said base and engageable with said second edge of said slot. a plate; characterised by a slot extending transversely to one edge of said plate, said slot being defined by first and second oppositely disposed edges and a third edge oriented transversely to said first and second edges; an insert removably mounted within said slot said insert comprising: a base engageable with said third edge of said slot; a first leg projecting transversely to said base and engageable with said first edge of said slot; a second leg projecting transversely to said base and engageable with said second edge of said slot. a base engageable with said third edge of said slot; a first leg projecting transversely to said base and engageable with said first edge of said slot; a second leg projecting transversely to said base and engageable with said second edge of said slot.
A feather product comprising: a feather bag body that includes a plurality of bag portions each accommodating feathers; a first film that covers a front side of the feather bag body and is formed of polyurethane; and a second film that covers a back side of the feather bag body and is formed of polyurethane, characterized in that the feather bag body is constituted by a pair of textiles (11a, 11b) and further includes a plurality of binding portions, which are formed by binding parts of the pair of textiles (11a, 11b) to each other by a binding yarn, and which surround an outer edge of each of the bag portions, and each textile (11a, 11b) is constituted by a yarn which is a multifilament. a feather bag body that includes a plurality of bag portions each accommodating feathers; a first film that covers a front side of the feather bag body and is formed of polyurethane; and a second film that covers a back side of the feather bag body and is formed of polyurethane, characterized in that the feather bag body is constituted by a pair of textiles (11a, 11b) and further includes a plurality of binding portions, which are formed by binding parts of the pair of textiles (11a, 11b) to each other by a binding yarn, and which surround an outer edge of each of the bag portions, and each textile (11a, 11b) is constituted by a yarn which is a multifilament.
Regulating circuit for the rotary speed regulation of a pulse-width modulated fan, including - a measuring device for determining a period duration (T Ist) of a tacho signal (TACH) of the fan; - a digital regulating register for detecting a regulating value for driving the fan depending upon a determined period duration (T Ist) and a target value (T Soll), - a digital control register for setting a duty ratio for driving the fan, wherein the digital control register has a smaller register width than the digital regulating register, and - control means, which are configured to update the digital control register through assessment of a predetermined number of higher-valued bits of the digital regulating register, wherein the measuring device includes a digital counter, the counter reading of which is changed by a predetermined value with each clock signal of an oscillator, wherein the period duration (T Ist) of a tacho signal (TACH) is determined on the basis of a difference between a first counter reading, upon receiving a first tacho pulse, and a second counter reading, upon receiving a second tacho pulse. - a measuring device for determining a period duration (T Ist) of a tacho signal (TACH) of the fan; - a digital regulating register for detecting a regulating value for driving the fan depending upon a determined period duration (T Ist) and a target value (T Soll), - a digital control register for setting a duty ratio for driving the fan, wherein the digital control register has a smaller register width than the digital regulating register, and - control means, which are configured to update the digital control register through assessment of a predetermined number of higher-valued bits of the digital regulating register, wherein the measuring device includes a digital counter, the counter reading of which is changed by a predetermined value with each clock signal of an oscillator, wherein the period duration (T Ist) of a tacho signal (TACH) is determined on the basis of a difference between a first counter reading, upon receiving a first tacho pulse, and a second counter reading, upon receiving a second tacho pulse.
Packaging machine for packaging a pourable product in at least one container, comprising: - a first filling station configured for filling the at least one container by means of a filling process of a first type, the first station being positioned at a first angular position around an axis, said axis being defined by the machine; - a second filling station configured for filling the at least one container by means of a filling process of a second type which is different from the first type, said second station being positioned at a second angular position around said axis and the second type being a contact filling process, said second angular position being different from said first angular position; the packaging machine being characterised by further comprising: - a control unit connected to said filling stations (3, 4) and configured to carry out a preliminary selection phase during which one of the filling stations (3, 4) is automatically selected as a function of an input from a user; - a conveyor configured to carry out a transporting phase, during which, by means at least of a stepwise rotational movement of the conveyor around said axis and with respect to said stations (3, 4), the at least one container is subsequently positioned in each of said stations (3, 4); wherein the machine is configured to carry out, as a function of said selection phase and during said transporting phase, a filling phase, during which the at least one container is filled with a pourable product, said filling phase being carried out by means of the selected station and while the at least one container is positioned in the selected station. - a first filling station configured for filling the at least one container by means of a filling process of a first type, the first station being positioned at a first angular position around an axis, said axis being defined by the machine; - a second filling station configured for filling the at least one container by means of a filling process of a second type which is different from the first type, said second station being positioned at a second angular position around said axis and the second type being a contact filling process, said second angular position being different from said first angular position; - a control unit connected to said filling stations (3, 4) and configured to carry out a preliminary selection phase during which one of the filling stations (3, 4) is automatically selected as a function of an input from a user; - a conveyor configured to carry out a transporting phase, during which, by means at least of a stepwise rotational movement of the conveyor around said axis and with respect to said stations (3, 4), the at least one container is subsequently positioned in each of said stations (3, 4);
A method of synthesising a Pt complex comprising: (i) a first step of preparing a reaction mixture comprising a water-soluble hexachloroplatinate salt having a solubility in water at 25 °C of at least 1 g/100 ml, and a compound according to Formula I', or salt thereof, and allowing the water-soluble hexachloroplatinate salt and the compound according to Formula I' to react wherein X is selected from OH, SH and NH 2, and Y and Z, together with the two carbon atoms to which they are attached, form an unsubstituted benzene group or an unsubstituted naphthalene group, an intermediate step, after the first step but before the second step, of adding an alcoholic reducing agent and heating the reaction mixture to an elevated temperature T 2 of at least 50 °C; (ii) a second step of adding a further quantity of the compound according to Formula I', or a salt thereof, to the reaction mixture. (i) a first step of preparing a reaction mixture comprising a water-soluble hexachloroplatinate salt having a solubility in water at 25 °C of at least 1 g/100 ml, and a compound according to Formula I', or salt thereof, and allowing the water-soluble hexachloroplatinate salt and the compound according to Formula I' to react wherein X is selected from OH, SH and NH 2, and Y and Z, together with the two carbon atoms to which they are attached, form an unsubstituted benzene group or an unsubstituted naphthalene group, an intermediate step, after the first step but before the second step, of adding an alcoholic reducing agent and heating the reaction mixture to an elevated temperature T 2 of at least 50 °C; X is selected from OH, SH and NH 2, and Y and Z, together with the two carbon atoms to which they are attached, form an unsubstituted benzene group or an unsubstituted naphthalene group, an intermediate step, after the first step but before the second step, of adding an alcoholic reducing agent and heating the reaction mixture to an elevated temperature T 2 of at least 50 °C; (ii) a second step of adding a further quantity of the compound according to Formula I', or a salt thereof, to the reaction mixture.