An Active-Matrix Organic Light Emitting Diode (AMOLED) display apparatus, comprising a display panel, wherein the display panel comprises a plurality of sub-pixels, each sub-pixel comprises an Organic Light Emitting Diode (OLED) and a pixel circuit for independently driving the OLED, characterized in that the AMOLED display apparatus further comprises: a drive chip, configured to output a corresponding data voltage to each sub-pixel and acquire a sensed voltage corresponding to each sub-pixel; and a Timing Controller (TCON), configured to: at an initial calibration stage, select at least a couple of preset brightness values identical for all the sub-pixels and apply for every selected preset value the corresponding initial data voltage to every sub-pixel of the display and measuring the resulting brightness of each sub-pixel by means of an image sensor; regulate the data voltage of each sub-pixel one by one, so that the measured brightness of all the sub-pixels is in a required uniform range for each preset value; when brightness uniformity of the display screen reaches the requirement, for any one sub-pixel, store the data voltage as a first data voltage of the each sub-pixel and the corresponding preset value into a memory; for every sub-pixel and for every preset value, output the corresponding stored data voltage to the pixel circuit of the sub-pixel, connect the drive transistor of the pixel circuit with the corresponding column oriented line so that the capacitance of the column oriented line is being charged, sense the voltage at the lines by means of Analog to Digital converters connected to the lines and storing the sensed voltages as initial reference voltages; at a later subsequent compensation stage, for every sub-pixel and for every preset value applying again the stored first data voltages, connect the drive transistor of the pixel circuit with the corresponding column oriented line so that the capacitance of the column oriented line is being charged, sense the voltage at the lines by means of Analog to Digital converters connected to the lines, and if the voltage sensed are not coincident with the stored initial reference voltages, make the sensed voltage corresponding to each sub-pixel to be equal to the corresponding initial reference voltage by modifying the applied first data voltage, so as to achieve uniform compensation on brightness of each sub-pixel at this compensation a drive chip, configured to output a corresponding data voltage to each sub-pixel and acquire a sensed voltage corresponding to each sub-pixel; and a Timing Controller (TCON), configured to: at an initial calibration stage, select at least a couple of preset brightness values identical for all the sub-pixels and apply for every selected preset value the corresponding initial data voltage to every sub-pixel of the display and measuring the resulting brightness of each sub-pixel by means of an image sensor; regulate the data voltage of each sub-pixel one by one, so that the measured brightness of all the sub-pixels is in a required uniform range for each preset value; when brightness uniformity of the display screen reaches the requirement, for any one sub-pixel, store the data voltage as a first data voltage of the each sub-pixel and the corresponding preset value into a memory; for every sub-pixel and for every preset value, output the corresponding stored data voltage to the pixel circuit of the sub-pixel, connect the drive transistor of the pixel circuit with the corresponding column oriented line so that the capacitance of the column oriented line is being charged, sense the voltage at the lines by means of Analog to Digital converters connected to the lines and storing the sensed voltages as initial reference voltages; at a later subsequent compensation stage, for every sub-pixel and for every preset value applying again the stored first data voltages, connect the drive transistor of the pixel circuit with the corresponding column oriented line so that the capacitance of the column oriented line is being charged, sense the voltage at the lines by means of Analog to Digital converters connected to the lines, and if the voltage sensed are not coincident with the stored initial reference voltages, make the sensed voltage corresponding to each sub-pixel to be equal to the corresponding initial reference voltage by modifying the applied first data voltage, so as to achieve uniform compensation on brightness of each sub-pixel at this compensation