mhurhangee/ep-ind-claims huggingface dataset:
An antibody or antigen-binding fragment thereof for use in the treatment of an anti-ganglioside or anti-glycolipid antibody mediated neuropathy in a mammal, wherein the antibody or antigen-binding fragment thereof binds to: (i) complement component C5 and inhibits the cleavage of C5 into fragments C5a and C5b; or (ii) C5b, wherein said antibody or antigen-binding fragment thereof inhibits the formation of the membrane attack complex; and wherein said anti-ganglioside or anti-glycolipid antibody mediated neuropathy is selected from the group consisting of: acute motor axonal neuropathy; acute inflammatory demyelinating polyneuropathy; Bickerstaff's brainstem encephalitis; acute ophthalmoparesis; ataxic Guillain-Barre syndrome; pharyngeal-cervical-brachial weakness; chronic neuropathy syndromes with anti-glycolipid antibodies; anti-MAG IgM paraproteinemic neuropathy; chronic sensory ataxic neuropathy with anti-disialosyl antibodies; IgM, IgG and IgA paraproteinemic neuropathy; motor neuropathy with anti-GM1 and anti-GM2 antibodies; chronic inflammatory demyelinating neuropathy (CIDP); multifocal motor neuropathy; and multifocal acquired demyelinating sensory and motor neuropathy (MADSAM). (i) complement component C5 and inhibits the cleavage of C5 into fragments C5a and C5b; or (ii) C5b,
Flow-control passive valve for controlling the flow of a fluid between an up-stream space at high pressure (p H) and a downstream space at low pressure (p L), the flow-control passive valve comprising a valve body (34, 36) in fluid communication on the one side with the up-stream space and on the other side with the downstream space, a first space and a second space being defined within the valve body (34, 36), a movable member slidably received in a chamber of the valve body (34, 36), resilient means applying on the movable member a force tending to keep it in a given non-working position, and metering means (56, 64, 68, 72, 76) for metering the flow of the fluid from the up-stream space to the downstream space through the valve body (34, 36), wherein said metering means (56, 64, 68, 72, 76) comprise a first fixed restrictor through which the first space is in fluid communication with the upstream space, a second fixed restrictor through which the first space is in fluid communication with the downstream space, a first variable restrictor (56, 72), the restriction amount of which depends on the position of the movable member and through which the first space is in fluid communication with the downstream space in parallel to the second fixed restrictor, a second variable restrictor (56, 68), the restriction amount of which depends on the position of the movable member and through which the first space is in fluid communication with the second space, and a third fixed restrictor (56, 40) through which the second space is in fluid communication with the downstream space, whereby the pressure (p 1) in the first space is lower than the pressure in the upstream space as a result of the pressure drop through the first fixed restrictor, while the pressure (p 2) in the second space is variable between the pressure (p 1) in the first space and the pressure (p L) in the downstream space depending on the position of the movable member.
An apparatus for steering a wheel having a wheel axle, comprising: a steering column (130, 230) defining an axis and a first horizontal distance extending from the axis to the wheel axle; a first fork leg (112, 212) extends along a first side of the steering column (130,230), the first fork leg (112,212) comprising a first fork portion; a lower crown (120, 220) is coupled to the steering column (130, 230), the lower crown (120, 220) defining a first pair of angled bores; and an upper crown (122, 222) is coupled to the steering column (130, 230), the upper crown (122, 222) defining a second pair of angled bores, wherein the first fork portion extends upwardly and forwardly from the steering column (130, 230), and the first fork leg (112, 212) is configured to support and position an object (144, 254) a second horizontal distance extending from the axis to the object (144, 254), wherein the second horizontal distance is greater than the first horizontal distance, characterized in that the first horizontal distance is extending perpendicularly from the axis to the wheel axle and the second horizontal distance is extending perpendicularly from the axis to the object (144, 254). a steering column (130, 230) defining an axis and a first horizontal distance extending from the axis to the wheel axle; a first fork leg (112, 212) extends along a first side of the steering column (130,230), the first fork leg (112,212) comprising a first fork portion; a lower crown (120, 220) is coupled to the steering column (130, 230), the lower crown (120, 220) defining a first pair of angled bores; and an upper crown (122, 222) is coupled to the steering column (130, 230), the upper crown (122, 222) defining a second pair of angled bores, wherein the first fork portion extends upwardly and forwardly from the steering column (130, 230), and the first fork leg (112, 212) is configured to support and position an object (144, 254) a second horizontal distance extending from the axis to the object (144, 254), wherein the second horizontal distance is greater than the first horizontal distance, characterized in that the first horizontal distance is extending perpendicularly from the axis to the wheel axle and the second horizontal distance is extending perpendicularly from the axis to the object (144, 254).
Braking installation for a railway train including a locomotive and a plurality of wagons for transporting goods, comprising a pneumatic brake pipe which extends along the train, and wherein the pressure is controlled by a braking control apparatus in the locomotive; an electrical power supply and communication line which likewise extends along the train, and which is coupled to an electronic control unit in the locomotive; the installation comprising further, in each wagon or in each group of associated wagons: an electronic module coupled to said electrical line through power supply and communication interface means (I, I1), and further connected to an electro-pneumatic control assembly designed for driving pneumatic brake valve means which are coupled to the pneumatic brake pipe and are adapted to apply to brake cylinders of the wagon or a group of wagons a braking pressure variable in a controlled manner; the electronic module being further connected to electrical sensor means (T1,..., Tn) associated with the electro-pneumatic assembly and/or the brake valve means for acquiring signals or data relating to values or states of predetermined quantities; the interface means (I, I1) comprising electronic processing and control means (MC, MC1) and transceiver means adapted to allow an exchange of information and/or data with said electronic control unit of the locomotive through said power supply and communication line, for controlling the braking of the wagon or group of wagons; the installation being characterized in that, in each wagon or group of wagons, a local communication network or bus (b) is positioned between the interface means (I, I1) and the electronic module, and additional transceiver means are provided, which are coupled to said electrical power supply and communication line, and which operate in a frequency band which is different from, possibly overlapping but broader than, that of said transceiver means; said processing and control means (MC, MC1) being designed for driving the additional transceiver means when said transceiver means are active and/or inactive, and for communicating to the electronic control unit of the locomotive information derived from the signals provided by said electrical sensor means (T1,..., Tn) to the electronic module and transferred by the latter to the interface means (I, I1) through said local communication network or bus (b).
A method of applying a discontinuous coating of a metal of IVB or VB group on the internal and external surfaces of a polymeric prosthesis of a blood vessel made of polyethylene terephthalate, including the following steps: - plasma-chemical modification of the polymeric prosthesis; - coating by magnetron sputtering method with an unbalanced plasma in an argon-oxygen plasma; wherein the coating is applied cyclically in the mode of alternating the process of magnetron sputtering with the process of ion etching. - plasma-chemical modification of the polymeric prosthesis; - coating by magnetron sputtering method with an unbalanced plasma in an argon-oxygen plasma; wherein the coating is applied cyclically in the mode of alternating the process of magnetron sputtering with the process of ion etching.
A mobile communication method in which a mobile station performs a handover from a handover-source radio base station to a handover-target radio base station, the method comprising the steps of: 'A' judging whether or not user plane data to be forwarded to the handover-target radio base station exists for each access bearer in S1 interface set up with an upper level node, when a handover for the mobile station is determined to be performed; 'B' notifying, to the handover-target radio base station, a result of the judgment by using a handover request message; 'C' setting up data forwarding tunnels for S1 handover for forwarding user plane data from the handover-source radio base station to the handover-target radio base station, the data forwarding tunnels for S1 handover are set up only for access bearers in S1 interface for which the user plane data to be forwarded exists, and notifying, to the handover-source radio base station, setup information on the data forwarding tunnels for S1 handover by using a handover request response message for the handover request message; and 'D' forwarding the user plane data to the handover-target radio base station by the handover-source radio base station via the data forwarding tunnels for S1 handover on the basis of the setup information on the data forwarding tunnels for S1 handover, characterized by an independent tunnel for X2 handover is set up for each bearer in X2 interface having data which needs forwarding from the handover-source radio base station to the handover-target radio base station. 'A' judging whether or not user plane data to be forwarded to the handover-target radio base station exists for each access bearer in S1 interface set up with an upper level node, when a handover for the mobile station is determined to be performed; 'B' notifying, to the handover-target radio base station, a result of the judgment by using a handover request message; 'C' setting up data forwarding tunnels for S1 handover for forwarding user plane data from the handover-source radio base station to the handover-target radio base station, the data forwarding tunnels for S1 handover are set up only for access bearers in S1 interface for which the user plane data to be forwarded exists, and notifying, to the handover-source radio base station, setup information on the data forwarding tunnels for S1 handover by using a handover request response message for the handover request message; and 'D' forwarding the user plane data to the handover-target radio base station by the handover-source radio base station via the data forwarding tunnels for S1 handover on the basis of the setup information on the data forwarding tunnels for S1 handover,
Valve (2; 102), notably for pressurized gas, comprising: - a body with: an inlet, an outlet, and a passage which connects the inlet with the outlet and which includes a seat; and - a sliding piston (18; 118) with two opposite faces, which is able to engage with the seat in order to close the passage; the valve (2; 102) being adapted in such a way that a differential pressure on opposite faces of the piston (18; 118) pulls away the piston (18; 118) from the seat in order to open the passage; characterized in that the piston (18; 118) is equipped with a telescopic extension (30; 130) sliding against the passage in order to guide the piston (18; 118) in the passage at least between the open position and the closed position. - a body with: an inlet, an outlet, and a passage which connects the inlet with the outlet and which includes a seat; and - a sliding piston (18; 118) with two opposite faces, which is able to engage with the seat in order to close the passage;
A child seat support device for a child seat placed on a seat cushion of a vehicle seat, the child seat support device being fixed to the vehicle seat, the child seat support device comprising: a fixed portion fixed to the child seat; and a movable portion supported via the fixed portion, the movable portion extending to a vehicle floor, wherein the movable portion includes: an automatic adjustment mechanism that changes a length of the movable portion from the fixed portion according to a height of the vehicle floor to bring a lower end portion of the movable portion into abutment with the vehicle floor; and a lock mechanism that stops an operation of the automatic adjustment mechanism in association with a change in acceleration of a vehicle. a fixed portion fixed to the child seat; and a movable portion supported via the fixed portion, the movable portion extending to a vehicle floor, wherein the movable portion includes: an automatic adjustment mechanism that changes a length of the movable portion from the fixed portion according to a height of the vehicle floor to bring a lower end portion of the movable portion into abutment with the vehicle floor; and a lock mechanism that stops an operation of the automatic adjustment mechanism in association with a change in acceleration of a vehicle. an automatic adjustment mechanism that changes a length of the movable portion from the fixed portion according to a height of the vehicle floor to bring a lower end portion of the movable portion into abutment with the vehicle floor; and a lock mechanism that stops an operation of the automatic adjustment mechanism in association with a change in acceleration of a vehicle.
An in vitro method for predicting the survival of a subject having stage I gastric cancer after tumor surgery, the method comprising: (a) determining the presence of activation or the level of activation of at least two analytes comprising cMET and HER1 in a cancer cell obtained from the subject, wherein cMET and HER1 are coactivated in the cancer cell; and (b) predicting the survival of the subject based upon the presence of activation or the level of activation of the at least two analytes determined in step (a), wherein the subject is predicted to have worse survival compared to stage I gastric cancer subjects with cMET activation in the absence of HER1 activation. (a) determining the presence of activation or the level of activation of at least two analytes comprising cMET and HER1 in a cancer cell obtained from the subject, wherein cMET and HER1 are coactivated in the cancer cell; and (b) predicting the survival of the subject based upon the presence of activation or the level of activation of the at least two analytes determined in step (a), wherein the subject is predicted to have worse survival compared to stage I gastric cancer subjects with cMET activation in the absence of HER1 activation.
A method comprising: providing a three-dimensional printed object, the printed object being formed from a printing composition comprising a solidifiable matrix and a microwave absorber dispersed in the solidifiable matrix; and applying a focused input of microwave radiation to the printed object at one or more locations, thereby heating the microwave absorber at the one or more locations and promoting consolidation of the printing composition within the printed object, characterized in that the microwave absorber comprises a plurality of carbon nanostructures dispersed in the solidifiable matrix, the carbon nanostructures comprising a plurality of carbon nanotubes that are branched, crosslinked, and share common walls with one another, and in that the carbon nanostructures are free of a growth substrate and are in the form of a flake material. providing a three-dimensional printed object, the printed object being formed from a printing composition comprising a solidifiable matrix and a microwave absorber dispersed in the solidifiable matrix; and applying a focused input of microwave radiation to the printed object at one or more locations, thereby heating the microwave absorber at the one or more locations and promoting consolidation of the printing composition within the printed object, characterized in that the microwave absorber comprises a plurality of carbon nanostructures dispersed in the solidifiable matrix, the carbon nanostructures comprising a plurality of carbon nanotubes that are branched, crosslinked, and share common walls with one another, and in that the carbon nanostructures are free of a growth substrate and are in the form of a flake material.
A para-type wholly aromatic copolyamide drawn fiber obtainable by a method comprising a high-tension hot drawing step of subjecting a para-type wholly aromatic copolyamide raw material fiber to hot drawing, the para-type wholly aromatic copolyamide raw material fiber being obtained by wet spinning or half-dry half-wet spinning from a para-type wholly aromatic copolyamide solution, the hot drawing being performed under a tension of 1% or more and less than 20% of the breaking tension of the para-type wholly aromatic copolyamide raw material fiber and at a temperature of 50°C or more and 450°C or less in such a manner that the para-type wholly aromatic copolyamide raw material fiber is not rubbed against metal of a device; the para-type wholly aromatic copolyamide drawn fiber having: a tensile elastic modulus of 630 cN/dtex or more; and a dry-heat creep of 2.0 × 10 -4 % or less after the lapse of 10 hours at 80°C. a tensile elastic modulus of 630 cN/dtex or more; and a dry-heat creep of 2.0 × 10 -4 % or less after the lapse of 10 hours at 80°C.
A transparent touch display device comprising: a substrate comprising: a pixel area, a first transmission area located on a first side of the pixel area, and a second transmission area located on a second side of the pixel area; a driving transistor disposed in the pixel area; an anode electrode disposed in the pixel area, located over the driving transistor, and electrically connected to a source electrode or a drain electrode of the driving transistor; an emission layer located on the anode electrode; a display cathode electrode located on the emission layer; a first touch cathode electrode disposed in the first transmission area and located on a first side of the display cathode electrode; a second touch cathode electrode disposed in the second transmission area and located on a second side of the display cathode electrode; a first touch line electrically connected to at least one of the first touch cathode electrode and the second touch cathode electrode; a first upper touch shield disposed over the first touch line and overlapping at least a portion of the first touch line, said first upper touch shield being capable of reducing or preventing influences between display driving and touch driving; and a first touch bridge that runs across the pixel area and electrically connects the first touch cathode electrode and the second touch cathode electrode, wherein the first touch bridge intersects the first touch line and is electrically connected to the first touch line. a substrate comprising: a pixel area, a first transmission area located on a first side of the pixel area, and a second transmission area located on a second side of the pixel area; a driving transistor disposed in the pixel area; an anode electrode disposed in the pixel area, located over the driving transistor, and electrically connected to a source electrode or a drain electrode of the driving transistor; an emission layer located on the anode electrode; a display cathode electrode located on the emission layer; a first touch cathode electrode disposed in the first transmission area and located on a first side of the display cathode electrode; a second touch cathode electrode disposed in the second transmission area and located on a second side of the display cathode electrode; a first touch line electrically connected to at least one of the first touch cathode electrode and the second touch cathode electrode; a first upper touch shield disposed over the first touch line and overlapping at least a portion of the first touch line, said first upper touch shield being capable of reducing or preventing influences between display driving and touch driving; and a first touch bridge that runs across the pixel area and electrically connects the first touch cathode electrode and the second touch cathode electrode, wherein the first touch bridge intersects the first touch line and is electrically connected to the first touch line.
A washing machine comprising a washing chamber for receiving a washing liquor and textile substrates to be cleaned, a reservoir () containing a plurality of water-insoluble solid particles, and a decolorizing device having an inlet for introducing washing liquor from the washing chamber into the decolorizing device and an outlet for discharging washing liquor from the decolorizing device into the washing chamber, and the decolorizing device further comprises at least one activating agent comprising a source of UV radiation and adapted to initiate within the decolorizing device a process for the formation of free radicals in the wash liquor as well as to regenerate the plurality of water-insoluble solid particles, characterized in that the water-insoluble solid particles a. comprise zeolites, clays and/or ceramics, and/or b. comprise polymer particles and the plurality of contaminated water-insoluble solid particles are regenerated by introduction, treatment using the activating agent and discharge from the decolorizing device. the water-insoluble solid particles a. comprise zeolites, clays and/or ceramics, and/or b. comprise polymer particles and a. comprise zeolites, clays and/or ceramics, and/or b. comprise polymer particles and the plurality of contaminated water-insoluble solid particles are regenerated by introduction, treatment using the activating agent and discharge from the decolorizing device.