mhurhangee/ep-ind-claims huggingface dataset:
A method of enriching for adult multipotential cells, the method comprising (i) contacting a cell sample with an anti-TNAP antibody under conditions that allows binding of the anti-TNAP antibody to cells expressing TNAP and separating cells bound to the anti-TNAP antibody; and (ii) culturing the cell population obtained in step (i) to enrich for multipotential cells expressing the STRO-1 marker; and wherein the anti-TNAP antibody is an antibody that binds to the same epitope as the STRO-3 antibody produced by the hybridoma cell line deposited with ATCC on 19 December 2005 under the provisions of the Budapest Treaty under deposit accession number PTA-7282. (i) contacting a cell sample with an anti-TNAP antibody under conditions that allows binding of the anti-TNAP antibody to cells expressing TNAP and separating cells bound to the anti-TNAP antibody; and (ii) culturing the cell population obtained in step (i) to enrich for multipotential cells expressing the STRO-1 marker; and wherein the anti-TNAP antibody is an antibody that binds to the same epitope as the STRO-3 antibody produced by the hybridoma cell line deposited with ATCC on 19 December 2005 under the provisions of the Budapest Treaty under deposit accession number PTA-7282.
Method for manufacturing fully solid thin-film micro-batteries, said micro-batteries comprising a layer of anode materials, referred to as anode layer, a layer of solid electrolyte materials, referred to as electrolyte layer, and a layer of cathode materials, referred to as cathode layer, in electrical contact with a cathode collector, characterised in that - a first electrode layer, cathode or anode, is deposited by electrophoresis on a substrate that is conductive or that has at least one conductive zone, said substrate or said at least one conductive zone able to serve as a current collector, anodic or cathodic, of said electrode of the micro-battery, - the electrolyte layer is deposited by electrophoresis on said first electrode layer, - a second electrode layer, anode or cathode, is deposited on the electrolyte layer by electrophoresis or by a vacuum deposition method. - a first electrode layer, cathode or anode, is deposited by electrophoresis on a substrate that is conductive or that has at least one conductive zone, said substrate or said at least one conductive zone able to serve as a current collector, anodic or cathodic, of said electrode of the micro-battery, - the electrolyte layer is deposited by electrophoresis on said first electrode layer, - a second electrode layer, anode or cathode, is deposited on the electrolyte layer by electrophoresis or by a vacuum deposition method.
An infection detection device, comprising: a housing having a display configured to output a level of infection at a surgical site; a probe having a proximal end portion attached to the housing and a distal end portion configured for insertion into a surgical site; and a detection device integrated along the probe, the detection device configured to measure a level of infection at a surgical site and communicate with the display to alert a user when a predetermined level of infection is detected at the surgical site, the detection device including a sterile applicator selectively attachable to the distal end portion of the probe, the sterile applicator configured to retrieve a tissue sample from the surgical site characterized in that the device further comprises a photometer configured to measure a level of infection from the tissue sample retrieved by the sterile applicator and wherein the photometer includes a reading chamber configured to receive the sterile applicator for testing a level of infection of the tissue sample therewith. a housing having a display configured to output a level of infection at a surgical site; a probe having a proximal end portion attached to the housing and a distal end portion configured for insertion into a surgical site; and a detection device integrated along the probe, the detection device configured to measure a level of infection at a surgical site and communicate with the display to alert a user when a predetermined level of infection is detected at the surgical site, the detection device including a sterile applicator selectively attachable to the distal end portion of the probe, the sterile applicator configured to retrieve a tissue sample from the surgical site characterized in that the device further comprises a photometer configured to measure a level of infection from the tissue sample retrieved by the sterile applicator and wherein the photometer includes a reading chamber configured to receive the sterile applicator for testing a level of infection of the tissue sample therewith.
An electrolyte composition comprising: a) a fluorinated solvent which is a fluorinated acyclic carboxylic acid ester represented by the formula R 1 -COO-R 2, wherein i) R 1 is H, an alkyl group, or a fluoroalkyl group; ii) R 2 is an alkyl group or a fluoroalkyl group; iii) either or both of R 1 and R 2 comprises fluorine; and iv) R 1 and R 2, taken as a pair, comprise at least two carbon atoms but not more than seven carbon atoms; b) a carbonate co-solvent; c) at least one γ-lactone represented by Formula wherein R 7, R 8, R 9, and R 10 is each independently H, F, a linear or branched C 1 to C 10 alkyl group, or a linear or branched C 1 to C 10 fluoroalkyl group; wherein the γ-lactone comprises 2(5 H)-furanone; and d) at least one electrolyte salt. a) a fluorinated solvent which is a fluorinated acyclic carboxylic acid ester represented by the formula R 1 -COO-R 2, wherein i) R 1 is H, an alkyl group, or a fluoroalkyl group; ii) R 2 is an alkyl group or a fluoroalkyl group; iii) either or both of R 1 and R 2 comprises fluorine; and iv) R 1 and R 2, taken as a pair, comprise at least two carbon atoms but not more than seven carbon atoms; i) R 1 is H, an alkyl group, or a fluoroalkyl group; ii) R 2 is an alkyl group or a fluoroalkyl group; iii) either or both of R 1 and R 2 comprises fluorine; and iv) R 1 and R 2, taken as a pair, comprise at least two carbon atoms but not more than seven carbon atoms; b) a carbonate co-solvent; c) at least one γ-lactone represented by Formula wherein R 7, R 8, R 9, and R 10 is each independently H, F, a linear or branched C 1 to C 10 alkyl group, or a linear or branched C 1 to C 10 fluoroalkyl group; wherein the γ-lactone comprises 2(5 H)-furanone; and d) at least one electrolyte salt.
MiR-146b-containing exosomes for use in the treatment of a subject suffering from brain cancer, wherein said exosomes are produced by the steps of: i. transfecting a multipotent mesenchymal stromal cell population capable of producing exosomes with a plasmid encoding miR-146b; ii. harvesting exosomes from the multipotent mesenchymal stromal cell population or media containing same after transfection; and iii. confirming the presence of miR-146b in one or more of the harvested exosomes. i. transfecting a multipotent mesenchymal stromal cell population capable of producing exosomes with a plasmid encoding miR-146b; ii. harvesting exosomes from the multipotent mesenchymal stromal cell population or media containing same after transfection; and iii. confirming the presence of miR-146b in one or more of the harvested exosomes.
Method for replacing sealing elements (6, 7) on a rolling bearing assembly comprising a rotatable element, a fixed element, and at least one bearing (2, 4) mounted between the rotatable element and the fixed element, at least one used sealing element (6, 7) being fast in rotation either with the rotatable element or the fixed element and having at least one sealing lip (62 1, 62 2; 62 6, 62 7) adapted to lay on a first surface (S1, S2) of the element with respect to which said used sealing element rotates, the method comprising a step consisting in mounting at least one replacement sealing element at the same place of the at least one used sealing element (6,7) so that at least one sealing lip (62 1 B, 62 2 B) of the replacement sealing element lays on a second surface (S3, S4) of the element with respect to which the used sealing element and the replacement sealing element rotate, this second surface (S3, S4) being located at a determined distance of the first surface (S1, S2), wherein it consists in providing a replacement sealing element having at least one sealing lip (62 1 B, 62 2 B) having a free edge (63 1 B, 63 2 B), which is located at said determined distance of a free edge (63 1, 63 2) of a corresponding sealing lip (62 1, 62 2) of the used sealing element.
Method for operating a turbomachine in the form of a heat pump, wherein a fluid guided through the turbomachine transmits kinetic energy to the turbomachine, the fluid has two fluid components and at least one fluid component of the fluid is compressible, and, in the working temperature range of the heat pump, the ratio c p /c V of the second fluid component is at least 1.1 times the ratio c p /c V of the first fluid component, and the fluid components are separated downstream of the turbomachine in a separator, and the first fluid component is accelerated and/or compressed downstream of the separator in a compressor (5.1) and the second fluid component is accelerated in a further compressor (5.2) downstream of the separator prior to the dissipation of thermal energy, characterised in that, downstream of the compressors (5.1, 5.2), the two fluid components are combined again in a mixer and in that the mass flows of the fluid components are dimensioned in such a way that an entropy flow I S1 of the first fluid component at the first compressor (5.1) is greater than an entropy flow I S2 of the second fluid component at the second compressor (5.2) and an entropy flow downstream of the mixer at the inlet of the turbomachine is the sum of I S1 and I S2.
Salt replacement product comprising substantially homogeneous particles of: a. 5 - 70 wt% of one or more extracts from fungi, like from mycelia or mushrooms; b. 10- 80 wt% of a chloride salt of a metal that is acceptable in food, chosen from calcium, magnesium, or mixtures thereof; c. and optionally one or more powder stabilizing additives. a. 5 - 70 wt% of one or more extracts from fungi, like from mycelia or mushrooms; b. 10- 80 wt% of a chloride salt of a metal that is acceptable in food, chosen from calcium, magnesium, or mixtures thereof; c. and optionally one or more powder stabilizing additives.
A method of separating a component of an absorbent article comprising: advancing a substrate in a machine direction; providing an ultra-short pulse laser source; emitting a laser beam with the ultra-short pulse laser source; directing the laser beam at a portion of the substrate; imparting a line of weakness into a portion of the substrate using the laser beam, wherein the laser beam is pulsed at a frequency from 100 kHz to 100 MHz, wherein the laser beam has a pulse duration from 5 femtoseconds to 10 picoseconds, and wherein the laser beam has a level of peak energy from 20 μJ to 875 μJ; forming a heat modified zone along the line of weakness; and separating the substrate along the line of weakness to form a separation edge, wherein the heat modified zone comprises a maximum width that is less than 200 microns, wherein the maximum width is measured from the separation edge in a direction perpendicular to the separation edge toward a central region of the substrate. advancing a substrate in a machine direction; providing an ultra-short pulse laser source; emitting a laser beam with the ultra-short pulse laser source; directing the laser beam at a portion of the substrate; imparting a line of weakness into a portion of the substrate using the laser beam, wherein the laser beam is pulsed at a frequency from 100 kHz to 100 MHz, wherein the laser beam has a pulse duration from 5 femtoseconds to 10 picoseconds, and wherein the laser beam has a level of peak energy from 20 μJ to 875 μJ; forming a heat modified zone along the line of weakness; and separating the substrate along the line of weakness to form a separation edge, wherein the heat modified zone comprises a maximum width that is less than 200 microns, wherein the maximum width is measured from the separation edge in a direction perpendicular to the separation edge toward a central region of the substrate.
A method of diagnosing colorectal cancer in a subject, comprising: • simultaneous measurement of the degrees of methylation of NPY and PENK genes or their fragments thereof as set forth in SEQ ID NO. 1 and SEQ ID No. 2 and • simultaneous measurement of the degrees of methylation of NPY and Wif1 genes or their fragments thereof as set forth in SEQ ID NO. 1 and SEQ ID No. 3, and • simultaneous measurement of the degrees of methylation of PENK and Wif1 genes or their fragments thereof set forth in SEQ ID NO. 2 and SEQ ID No. 3 in a biological sample obtained from said subject. • simultaneous measurement of the degrees of methylation of NPY and PENK genes or their fragments thereof as set forth in SEQ ID NO. 1 and SEQ ID No. 2 and • simultaneous measurement of the degrees of methylation of NPY and Wif1 genes or their fragments thereof as set forth in SEQ ID NO. 1 and SEQ ID No. 3, and • simultaneous measurement of the degrees of methylation of PENK and Wif1 genes or their fragments thereof set forth in SEQ ID NO. 2 and SEQ ID No. 3
A damping track structure system having a multi-layer design and comprising a filling layer, an elastic cushion and a prefabricated track slab, the filling layer, the elastic cushion and the prefabricated track slab being arranged, in use, from the bottom to the top wherein the elastic cushion is laid on the filling layer, the elastic cushion and the prefabricated slab are compounded as a whole, the prefabricated track slab is arranged on the elastic cushion for damping, the prefabricated track slab is provided with two parallel steel rails, each of which being respectively fixed on the track slab by a plurality of fasteners, wherein the middle part of the track slab is provided with 2 holes, wherein the holes are arranged to penetrate the prefabricated track slab and the elastic cushion through the thickness direction of the track slab, wherein a sealing sleeve is installed in the holes, wherein the sealing sleeve is of a cylinder structure made of elastic material. a filling layer, an elastic cushion and a prefabricated track slab, the filling layer, the elastic cushion and the prefabricated track slab being arranged, in use, from the bottom to the top wherein the elastic cushion is laid on the filling layer, the elastic cushion and the prefabricated slab are compounded as a whole, the prefabricated track slab is arranged on the elastic cushion for damping, the prefabricated track slab is provided with two parallel steel rails, each of which being respectively fixed on the track slab by a plurality of fasteners, wherein the middle part of the track slab is provided with 2 holes, wherein the holes are arranged to penetrate the prefabricated track slab and the elastic cushion through the thickness direction of the track slab, wherein a sealing sleeve is installed in the holes, wherein the sealing sleeve is of a cylinder structure made of elastic material.
A transport refrigeration system comprising: a tractor vehicle having an engine; a trailer operably coupled to the tractor vehicle; a transport refrigeration unit mounted to a front surface of the trailer adjacent the tractor vehicle; and at least one shield (50; 52, 54) mounted to the tractor or the trailer; characterised in that the at least one shield is configured to divert discharged hot air from the vehicle engine away from a flow path towards a condenser air inlet of the transport refrigeration unit. a tractor vehicle having an engine; a trailer operably coupled to the tractor vehicle; a transport refrigeration unit mounted to a front surface of the trailer adjacent the tractor vehicle; and at least one shield (50; 52, 54) mounted to the tractor or the trailer; characterised in that the at least one shield is configured to divert discharged hot air from the vehicle engine away from a flow path towards a condenser air inlet of the transport refrigeration unit.
A method of making a fluid flow device comprising: providing a substrate of porous material impregnated with a light-sensitive substance in a first state and which is configured to change state from the first state to a second state when exposed to light, the first state being removable with a solvent and the second state being a solid state that is resistant to the solvent, the substrate having a fluid flow channel defined therein, and the channel having a depth; exposing a beam of light onto an area of the substrate surface within the fluid flow channel to deliver energy to a volume of the substrate below the area to change the light-sensitive substance to the second state; and developing the substrate in the solvent to leave the light-sensitive substance which is in the solid state and remove the light-sensitive substance which is in the first state; wherein the light-sensitive substance in the first state comprises a polymerisable substance containing monomers which, when exposed to light, bond to form a polymer comprising the second state; characterised by during exposure, creating a partial barrier to flow of fluid along the channel by controlling the amount of energy delivered to the volume below at least part of the area to change the light-sensitive substance to the second state in a volume of the substrate within the fluid flow channel that has a depth less than the depth of the fluid flow channel. providing a substrate of porous material impregnated with a light-sensitive substance in a first state and which is configured to change state from the first state to a second state when exposed to light, the first state being removable with a solvent and the second state being a solid state that is resistant to the solvent, the substrate having a fluid flow channel defined therein, and the channel having a depth; exposing a beam of light onto an area of the substrate surface within the fluid flow channel to deliver energy to a volume of the substrate below the area to change the light-sensitive substance to the second state; and developing the substrate in the solvent to leave the light-sensitive substance which is in the solid state and remove the light-sensitive substance which is in the first state; wherein the light-sensitive substance in the first state comprises a polymerisable substance containing monomers which, when exposed to light, bond to form a polymer comprising the second state; characterised by during exposure, creating a partial barrier to flow of fluid along the channel by controlling the amount of energy delivered to the volume below at least part of the area to change the light-sensitive substance to the second state in a volume of the substrate within the fluid flow channel that has a depth less than the depth of the fluid flow channel.
A method of determining an alignment level between motion compensated reference patches, the method comprising: obtaining, by a decoder, motion compensated interpolated samples based on sub-pixel accurate merge motion vectors from a bilinear motion compensated interpolation; computing, by the decoder, a sum of absolute differences, SAD, between two motion compensated reference patches using a subset of the motion compensated interpolated samples; determining, by the decoder, whether the SAD is less than a coding unit, CU, size-dependent threshold value, wherein the CU size-dependent threshold value is a function of a number of samples in the subset of motion compensated interpolated samples; when the SAD is less than the CU size-dependent threshold value: skipping remaining decoder-side motion vector refinement, DMVR process steps; and performing final motion compensation; and when the SAD is not less than the CU size-dependent threshold value: performing the remaining DMVR process steps; and performing the final motion compensation, the method characterised in that the production of the interpolated samples across the two reference patches is interleaved such that the SAD is computed at the earliest possible time rather than waiting for all interpolated samples to be produced. obtaining, by a decoder, motion compensated interpolated samples based on sub-pixel accurate merge motion vectors from a bilinear motion compensated interpolation; computing, by the decoder, a sum of absolute differences, SAD, between two motion compensated reference patches using a subset of the motion compensated interpolated samples; determining, by the decoder, whether the SAD is less than a coding unit, CU, size-dependent threshold value, wherein the CU size-dependent threshold value is a function of a number of samples in the subset of motion compensated interpolated samples; when the SAD is less than the CU size-dependent threshold value: skipping remaining decoder-side motion vector refinement, DMVR process steps; and performing final motion compensation; and skipping remaining decoder-side motion vector refinement, DMVR process steps; and performing final motion compensation; and when the SAD is not less than the CU size-dependent threshold value: performing the remaining DMVR process steps; and performing the final motion compensation, performing the remaining DMVR process steps; and performing the final motion compensation,
A housing for a lighting device, wherein the housing comprises an elongate base region and opposing elongate sidewalls extending from opposite elongate sides of the elongate base region towards respective terminal ends, wherein each of the opposing elongate sidewalls has an optically transmissive inner surface separated from an outer surface by a distance of 5 millimeters or less to form a cavity for housing a reflective foil or a thermally conductive member, wherein the inner surface extends across the elongate base region, and wherein the inner surface comprises a recess in the elongate base region for housing a light engine, wherein the housing further comprises a light exit window (17, 17') extending across the respective terminal ends of the opposing elongate sidewalls distal to the elongate base region.