mhurhangee/ep-ind-claims huggingface dataset:
A method of identifying whether a subject having androgenetic alopecia, baldness or hair loss is likely to be responsive to administration of a DP-2 antagonist that is selective with respect to DP-1 to stimulate hair growth, comprising: (i) genotyping single nucleotide polymorphic loci within or flanking the DP-2 gene in a genomic DNA sample obtained from the subject; and (ii) determining whether the subject is likely to be responsive to administration of the DP-2 antagonist, based on the genotype detected at each of the loci, wherein the loci comprise rs545659, rs634681 and rs7167, and wherein allele C of rs545659, allele A of rs634681 and allele G of rs7167 indicate that the subject is likely to be responsive. (i) genotyping single nucleotide polymorphic loci within or flanking the DP-2 gene in a genomic DNA sample obtained from the subject; and (ii) determining whether the subject is likely to be responsive to administration of the DP-2 antagonist, based on the genotype detected at each of the loci,
A cleaning apparatus, comprising: a cleaning head having a lower edge, including: an annular steam chamber enclosing a vacuum chamber, the annular steam chamber having a plurality of apertures located in vertically spaced relation to the lower edge; and a steam nozzle configured to provide steam to the annular steam chamber for discharge through the apertures and into the vacuum chamber. a cleaning head having a lower edge, including: an annular steam chamber enclosing a vacuum chamber, the annular steam chamber having a plurality of apertures located in vertically spaced relation to the lower edge; and a steam nozzle configured to provide steam to the annular steam chamber for discharge through the apertures and into the vacuum chamber. an annular steam chamber enclosing a vacuum chamber, the annular steam chamber having a plurality of apertures located in vertically spaced relation to the lower edge; and a steam nozzle configured to provide steam to the annular steam chamber for discharge through the apertures and into the vacuum chamber.
A Trichoderma cell comprising at least three endogenous proteases having reduced or eliminated activity, and a recombinant polynucleotide encoding a heterologous polypeptide, wherein the Trichoderma cell has reduced or eliminated activity in at least gap 1 protease of SEQ ID NO: 118 and at least 2 further proteases selected from the list of pep2 of SEQ ID NO: 182, pep3 of SEQ ID NO: 17, pep4 of SEQ ID NO: 37, pep5 of SEQ ID NO: 58, pep8 of SEQ ID NO: 507, pep11 of SEQ ID NO: 522, pep12 of SEQ ID NO: 530, tsp1 of SEQ ID NO: 66, slp1 of SEQ ID NO: 82, slp2 of SEQ ID NO: 98, slp3 of SEQ ID NO: 166, slp7 of SEQ ID NO: 231, pep1 of SEQ ID NO: 1 and gap2 of SEQ ID NO: 129 and wherein the total protease activity of the Trichoderma cell is reduced to 49% or less, of the total protease activity of the corresponding parental Trichoderma cell in which said proteases do not have the reduced activity.
A method for diagnosing a cancerous disease characterized by expression or abnormal expression of a tumor-associated antigen, which method comprises (i) detecting a nucleic acid which codes for the tumor-associated antigen, and/or (ii) detecting the tumor-associated antigen, in a biological sample isolated from a patient, wherein the tumor-associated antigen has a sequence which is encoded by a nucleic acid selected from the group consisting of: (a) a nucleic acid which comprises a nucleic acid sequence according to SEQ ID NO: 40, (b) a nucleic acid which hybridizes with the nucleic acid of (a) under stringent conditions, (c) a nucleic acid which is degenerate with respect to the nucleic acid of (a) or (b), and (d) a nucleic acid which is complementary to the nucleic acid of (a), (b) or (c). (i) detecting a nucleic acid which codes for the tumor-associated antigen, and/or (ii) detecting the tumor-associated antigen, (a) a nucleic acid which comprises a nucleic acid sequence according to SEQ ID NO: 40, (b) a nucleic acid which hybridizes with the nucleic acid of (a) under stringent conditions, (c) a nucleic acid which is degenerate with respect to the nucleic acid of (a) or (b), and (d) a nucleic acid which is complementary to the nucleic acid of (a), (b) or (c).
A yarn monitoring device comprising: a yarn passage defining member including a wall surface adapted to define a yarn passage for enabling passage of a yarn travelling along a yarn path, a detecting section (37, 38) adapted to detect at least at a portion of the wall surface, status of the yarn, and a blowing section adapted to blow fluid in a blowing direction towards at least a portion of the wall surface (35, 38, 39), characterized in that the blowing section is configured such that when viewed in a direction orthogonal to the yarn path and parallel to the wall surface (35, 38, 39), the blowing direction is set diagonal to the wall surface (35, 38, 39) and the fluid flows along the wall surface (35, 38, 39). a yarn passage defining member including a wall surface adapted to define a yarn passage for enabling passage of a yarn travelling along a yarn path, a detecting section (37, 38) adapted to detect at least at a portion of the wall surface, status of the yarn, and a blowing section adapted to blow fluid in a blowing direction towards at least a portion of the wall surface (35, 38, 39), characterized in that the blowing section is configured such that when viewed in a direction orthogonal to the yarn path and parallel to the wall surface (35, 38, 39), the blowing direction is set diagonal to the wall surface (35, 38, 39) and the fluid flows along the wall surface (35, 38, 39).
Self-propelling harvesting machine with a harvesting header to which a mulching implement is attached, wherein the mulching implement comprises the following: at least one processing tool, which can be set into movement by means of a drive, for shredding plant stumps, a holder of the processing tool, which holder is attached to the harvesting header in a position-adjustable manner, and means for controlling the position of the holder in relation to the harvesting header, which means comprise an externally actuated actuator which is connected to a controller for controlling the actuator, characterized in that the actuator is designed for controlling the ground pressing force of the holder during the harvesting mode, in that the controller is connected to an operator interface with which the force exerted on the holder by the actuator during the harvesting mode can be predetermined and the controller can be operated to activate the actuator in such a manner that the actuator acts on the holder with the predetermined force. at least one processing tool, which can be set into movement by means of a drive, for shredding plant stumps, a holder of the processing tool, which holder is attached to the harvesting header in a position-adjustable manner, and means for controlling the position of the holder in relation to the harvesting header, which means comprise an externally actuated actuator which is connected to a controller for controlling the actuator, characterized in that the actuator is designed for controlling the ground pressing force of the holder during the harvesting mode, in that the controller is connected to an operator interface with which the force exerted on the holder by the actuator during the harvesting mode can be predetermined and the controller can be operated to activate the actuator in such a manner that the actuator acts on the holder with the predetermined force.
A system for controlling an automatic parking brake, comprising: a control valve having an inlet for coupling to a source of brake pipe pressure, an outlet for coupling to a control inlet of the automatic parking brake, and a pilot for coupling to the source of brake pipe pressure, wherein the control valve is moveable between a first position where the inlet is in communication with the outlet and a second position where the inlet and the outlet are isolated from each other in response to a predetermined amount of brake pipe pressure at the pilot.
A pilot nozzle for a dual fuel turbine engine comprising: an inner air circuit; a gaseous fuel circuit radially outward from the inner air circuit; a liquid fuel circuit radially outward from the inner air circuit; an outer air circuit radially outward from the liquid fuel circuit and the gaseous fuel circuit; and a shroud radially outward from the outer air circuit configured to stabilize a pilot re-circulation zone downstream from outlets of the inner and outer air circuits (108, 114) and the liquid and gaseous fuel circuits (112, 110), wherein the shroud defines a longitudinal axis and includes an upstream end at a first axial position proximate to the outer air circuit and a downstream end at a second axial position downstream from the outlets of the inner and outer air circuits (108, 114) and the liquid and gaseous fuel circuits (112, 110); and wherein only the downstream end of the shroud includes a diverging portion. an inner air circuit; a gaseous fuel circuit radially outward from the inner air circuit; a liquid fuel circuit radially outward from the inner air circuit; an outer air circuit radially outward from the liquid fuel circuit and the gaseous fuel circuit; and a shroud radially outward from the outer air circuit configured to stabilize a pilot re-circulation zone downstream from outlets of the inner and outer air circuits (108, 114) and the liquid and gaseous fuel circuits (112, 110), wherein the shroud defines a longitudinal axis and includes an upstream end at a first axial position proximate to the outer air circuit and a downstream end at a second axial position downstream from the outlets of the inner and outer air circuits (108, 114) and the liquid and gaseous fuel circuits (112, 110); and wherein only the downstream end of the shroud includes a diverging portion.
A method for mitigating thermal degradation in a portable computing device, PCD, the method comprising: determining that a power frequency associated with a processing component positioned within the PCD is substantially zero, wherein current remaining on a power rail associated with the processing component corresponds to a presence of a leakage current associated with the processing component, wherein determining that the power frequency associated with the processing component positioned within the PCD is substantially zero comprises recognizing that a "wait for interrupt" instruction has been given to the processing component; after having recognized that the "wait for interrupt" instruction has been given to the processing component, measuring the leakage current on the power rail associated with the processing component; based on the measured leakage current, determining a thermal status of the processing component, wherein the thermal status is determined to be one of various thermal statuses each of which corresponds to a respective temperature range of the processing component; and based on the thermal status of the processing component, implementing thermal management policies to mitigate thermal degradation of the processing component. determining that a power frequency associated with a processing component positioned within the PCD is substantially zero, wherein current remaining on a power rail associated with the processing component corresponds to a presence of a leakage current associated with the processing component, wherein determining that the power frequency associated with the processing component positioned within the PCD is substantially zero comprises recognizing that a "wait for interrupt" instruction has been given to the processing component; after having recognized that the "wait for interrupt" instruction has been given to the processing component, measuring the leakage current on the power rail associated with the processing component; based on the measured leakage current, determining a thermal status of the processing component, wherein the thermal status is determined to be one of various thermal statuses each of which corresponds to a respective temperature range of the processing component; and based on the thermal status of the processing component, implementing thermal management policies to mitigate thermal degradation of the processing component.
A method for returning substantially emptied winding shafts from an unwinder of a fibrous web back to a winder of a fibrous web after being emptied, the winding shafts (3, 4) being returned at the side of the track, characterized in that after being transferred to the side from the unwinder, the winding shaft is turned by means of a first turning device located at the unwinder in the horizontal plane by substantially 90 degrees to lie parallel to the track before return transfer in a direction opposite to the track's direction, and before being returned to the winder the empty winding shaft is again turned by means of a second turning device located at the winder by substantially 90 degrees in the horizontal plane, and it is returned to the track in a direction perpendicular to the track's moving direction, and wherein the transfer is carried out in a parallel orientation relative to the track by means of at least one transfer cart reciprocating between the turning devices (11, 12) at the winding stations.
A method of recharging a reducing agent of an SCR catalyst of an exhaust system for an internal combustion engine by periodically dosing, under control of an electronic control system, a thermally decomposable substance into the exhaust system, the method comprising: determining that recharging of the SCR catalyst is required because of depletion of the reducing agent on the SCR catalyst; determining whether the temperature of exhaust gas in a recharging region of the exhaust system is in a first range or a second range above the first range, wherein in the first range the substance cannot thermally decompose and in the second range the substance can thermally decompose, wherein the recharging region is upstream of the SCR catalyst; in response to a determination that both recharging of the SCR catalyst is required because of depletion of the reducing agent on the SCR catalyst and the temperature of the exhaust gas in the recharging region is in the second range, injecting the thermally decomposable substance into the recharging region to recharge the SCR catalyst; and in response to a determination that both recharging of the SCR catalyst is required because of depletion of the reducing agent on the SCR catalyst and the temperature of the exhaust gas in the recharging region is in the first range, raising the temperature of the exhaust gas in the recharging region into the second range, and injecting the thermally decomposable substance into the recharging region to recharge the SCR catalyst. determining that recharging of the SCR catalyst is required because of depletion of the reducing agent on the SCR catalyst; determining whether the temperature of exhaust gas in a recharging region of the exhaust system is in a first range or a second range above the first range, wherein in the first range the substance cannot thermally decompose and in the second range the substance can thermally decompose, wherein the recharging region is upstream of the SCR catalyst; in response to a determination that both recharging of the SCR catalyst is required because of depletion of the reducing agent on the SCR catalyst and the temperature of the exhaust gas in the recharging region is in the second range, injecting the thermally decomposable substance into the recharging region to recharge the SCR catalyst; and in response to a determination that both recharging of the SCR catalyst is required because of depletion of the reducing agent on the SCR catalyst and the temperature of the exhaust gas in the recharging region is in the first range, raising the temperature of the exhaust gas in the recharging region into the second range, and injecting the thermally decomposable substance into the recharging region to recharge the SCR catalyst.
Pulled agricultural device with a frame and a supporting device which is arranged on the rear side of the frame and has at least two running wheels, which are arranged at a distance from one another transversely with respect to the direction of travel, and is designed as a chassis with a chassis rocker and has at least one linkage having upper and lower rockers (9, 11) which form a four-bar linkage, wherein the rockers (9, 11) are arranged pivotably in a vertical plane on the frame by means of at least front joints (12, 13), wherein the rockers (9, 10) have rear joints (14, 15), at which the chassis rocker having running wheels is articulated, wherein a motorized actuating cylinder, preferably hydraulic cylinder, which can pivot the lower rocker is arranged between the frame and the lower rockers (9, 11) and the chassis rocker, wherein the lower rocker has at least two longitudinal members arranged spaced apart from one another, characterized in that the longitudinal members of the lower rocker of the four-bar linkage are of curved design and are arranged in such a manner that the convex sides are adjacent to one another, in that the outer contour of the lower rocker of the four-bar linkage is formed in a tapered manner, as seen in top view, in that the longitudinal members of the lower rocker of the four-bar linkage are arranged in a mirror-inverted manner with respect to one another in such a manner that the longitudinal members of the lower rocker of the four-bar linkage are connected to one another by means of a connecting piece in the region where they lie closest to one another, in that, in the region of the connecting piece, the actuating cylinder acts on the lower rocker of the four-bar linkage, and in that the rocker is formed integrally.
A method for determining the susceptibility of a live substance to one or more test substances comprising: culturing one or more live substances, wherein the live substance comprises one or more of prokaryotic microorganisms, eukaryotic microorganisms, bacteria, archaea, protists, fungi, plant cells, animal cells, viruses in host cells, phages in host cells, cancer cell culture, and tissue cell culture, at a plurality of test locations of a test vessel (100, 902), the test locations including a thermochromic material and one or more test substances, where the test vessel (100, 902) comprises a microtiter plate and the plurality of test locations comprise test wells of the microtiter plate; detecting a spectral shift in light emanating from the thermochromic material of the test locations, the spectral shift occurring in response to an increase or decrease in energy conversion by the live substance; and determining an effect of the one or more test substances on the live substances based on the detected spectral shift. culturing one or more live substances, wherein the live substance comprises one or more of prokaryotic microorganisms, eukaryotic microorganisms, bacteria, archaea, protists, fungi, plant cells, animal cells, viruses in host cells, phages in host cells, cancer cell culture, and tissue cell culture, at a plurality of test locations of a test vessel (100, 902), the test locations including a thermochromic material and one or more test substances, where the test vessel (100, 902) comprises a microtiter plate and the plurality of test locations comprise test wells of the microtiter plate; detecting a spectral shift in light emanating from the thermochromic material of the test locations, the spectral shift occurring in response to an increase or decrease in energy conversion by the live substance; and determining an effect of the one or more test substances on the live substances based on the detected spectral shift.
A topical skin composition comprising an effective amount of ornithine, retinol, Commiphora mukul resin, and hyaluronic acid or a salt thereof to reduce the appearance of a wrinkle on skin, wherein the composition further comprises a dermatologically acceptable vehicle, wherein the retinol and the Commiphora mukul resin are each encapsulated.
A cleaning tool, having a cleaning sheet and a holder for holding the cleaning sheet, wherein: the cleaning sheet is configured to extend in a longitudinal direction which is defined by a direction of insertion of the holder into the cleaning sheet, and in a transverse direction which is defined by a direction crossing the longitudinal direction, the holder has a holding part for holding the cleaning sheet, and a grip part which is connected to the holding part and designed to be held by a user, the cleaning sheet has a brush part capable of cleaning an object to be cleaned, a base connected with the brush part, and an insertion part which is formed on the base and into which the holding part is inserted, the brush part has a plurality of strips formed by strip-like sheets, characterized in that the strips include first strips and second strips having a higher rigidity than the first strips, and each of the second strips has a scraping-out part capable of scraping out dust on the object to be cleaned. the cleaning sheet is configured to extend in a longitudinal direction which is defined by a direction of insertion of the holder into the cleaning sheet, and in a transverse direction which is defined by a direction crossing the longitudinal direction, the holder has a holding part for holding the cleaning sheet, and a grip part which is connected to the holding part and designed to be held by a user, the cleaning sheet has a brush part capable of cleaning an object to be cleaned, a base connected with the brush part, and an insertion part which is formed on the base and into which the holding part is inserted, the brush part has a plurality of strips formed by strip-like sheets, characterized in that the strips include first strips and second strips having a higher rigidity than the first strips, and each of the second strips has a scraping-out part capable of scraping out dust on the object to be cleaned.
SMDP server (110a, 110b) having: a profile generator for generating a profile of a user of an electronic SIM, eSIM; a PIN generator for generating a personal identification number, PIN, of the electronic SIM; and a communication interface for transmitting the profile with information relating to the PIN to an eSIM circuit of a communication device (210a, 210b), characterized in that the PIN generator is configured to generate a key and a challenge according to a challenge-response method, with the result that the PIN can be determined from the key and the challenge using a cryptographic algorithm; and the profile generator is configured to write the key and the cryptographic algorithm into the profile. a profile generator for generating a profile of a user of an electronic SIM, eSIM; a PIN generator for generating a personal identification number, PIN, of the electronic SIM; and a communication interface for transmitting the profile with information relating to the PIN to an eSIM circuit of a communication device (210a, 210b),
A radiation therapy system comprising: means configured to load a planning image of a target in a human; means configured to monitor the position of said target; means configured to compute an occurrence of substantial alignment between the position of said target and said target of said planning image wherein said computing comprises utilizing a sum of a real-time deformation vector-field; and means configured to enable triggering, after said computing, of a beam of radiation to deliver an entire dosage or a fraction of a dosage to said target in less than a second. means configured to load a planning image of a target in a human; means configured to monitor the position of said target; means configured to compute an occurrence of substantial alignment between the position of said target and said target of said planning image wherein said computing comprises utilizing a sum of a real-time deformation vector-field; and means configured to enable triggering, after said computing, of a beam of radiation to deliver an entire dosage or a fraction of a dosage to said target in less than a second.