mhurhangee/ep-ind-claims huggingface dataset:
An assembly for acting on an outer surface of a tube of a nuclear reactor, the assembly comprising: - a carrier movable along the tube; - at least one inspection or maintenance tool (81, 111, 123), connected to the carrier; the carrier comprising: - at least one rolling body, placed in contact with the outer surface of the tube; - an actuator, arranged to rotate the rolling body relative to the tube, so as to propel the carrier along the tube by cooperation between the rolling body and the outer surface of the tube; - a device for connecting the carrier to the tube, arranged so that the tube absorbs at least 50% of the weight of the carrier and the tool (81, 111, 123); characterized in that one of the tools is a machining tool including at least one machining device able to machine the outer surface of the tube and to gouge damaged areas of the outer surface of the tube, preferably two machining devices that are diametrically opposite relative to the tube, and in that the machining tool includes: - a frame; - a plurality of guide rollers connected to the frame, arranged to cooperate with the tube such that the machining tool is supported by the tube and is able to move along the tube; - a carriage carrying the or each machining devices; - a connection of the carriage to the frame, arranged so that the carriage is translatable longitudinally relative to the frame along the tube and circumferentially rotatable around the tube. - a carrier movable along the tube; - at least one inspection or maintenance tool (81, 111, 123), connected to the carrier; - at least one rolling body, placed in contact with the outer surface of the tube; - an actuator, arranged to rotate the rolling body relative to the tube, so as to propel the carrier along the tube by cooperation between the rolling body and the outer surface of the tube; - a device for connecting the carrier to the tube, arranged so that the tube absorbs at least 50% of the weight of the carrier and the tool (81, 111, 123); - a frame; - a plurality of guide rollers connected to the frame, arranged to cooperate with the tube such that the machining tool is supported by the tube and is able to move along the tube; - a carriage carrying the or each machining devices; - a connection of the carriage to the frame, arranged so that the carriage is translatable longitudinally relative to the frame along the tube and circumferentially rotatable around the tube.
A fall protection safety method comprising the steps of: - providing a fall protection anchoring device, apt to allow an operator to work safely on a roof or another fixed structure of a building, comprising a main body having an anchoring portion having a thickness and developing along a direction of development at least partially in a reference plane and intended for being anchored on a first end thereof to a personal protection device worn by the operator, said main body further having at least a first fastening portion and a second fastening portion, intended for being fastened on a respective first end (7a, 8a) thereof to the fixed structure of the building, and integral, in correspondence of a respective second end (7b, 8b) thereof, opposed to said first end, with said anchoring portion, said first and second fastening portion (7, 8) being arranged in two opposed half-spaces with respect to said reference plane and lying at least partially on a respective support plane, at least one of which being transversal to said reference plane, and - installing said device on a fixed structure of a building, so that said first fastening portion and/or said second fastening portion is fastened to said fixed structure, and said first end of said anchoring portion protrudes from the fixed structure, characterized in that said anchoring portion comprises in correspondence of a second end thereof, opposed to said first end, a notch through said thickness and apt to divide along a separation line corresponding to said notch said second end of the anchoring portion into two sub-portions (70, 80), said first fastening portion and second fastening portion being integral with said two sub-portions (70, 80), respectively, and developing from a respective end segment (97, 98) of said two sub-portions. - providing a fall protection anchoring device, apt to allow an operator to work safely on a roof or another fixed structure of a building, comprising a main body having an anchoring portion having a thickness and developing along a direction of development at least partially in a reference plane and intended for being anchored on a first end thereof to a personal protection device worn by the operator, said main body further having at least a first fastening portion and a second fastening portion, intended for being fastened on a respective first end (7a, 8a) thereof to the fixed structure of the building, and integral, in correspondence of a respective second end (7b, 8b) thereof, opposed to said first end, with said anchoring portion, said first and second fastening portion (7, 8) being arranged in two opposed half-spaces with respect to said reference plane and lying at least partially on a respective support plane, at least one of which being transversal to said reference plane, and - installing said device on a fixed structure of a building, so that said first fastening portion and/or said second fastening portion is fastened to said fixed structure, and said first end of said anchoring portion protrudes from the fixed structure,
A compound of formula wherein n, q and m are zero or an integer from 1 to 2; R 1 is selected from the group consisting of -H, halogen, -CN, (C 1 -C 6) alkyl, R 2 and R 3, the same or different, are selected from the group consisting of -H, (C 1 -C 6) alkyl, (C 1 -C 6) haloalkyl, (C 1 -C 6) hydroxyalkyl, (C 1 -C 6) aminoalkyl, (C 1 -C 6) alkoxy (C 1 -C 6) alkyl, heteroaryl(C 1 -C 6)alkyl, each of said heteroaryl is further optionally substituted by one or more group selected independently from halogen, -CN, -OH, (C 1 -C 8)alkyl, (C 1 -C 6) haloalkyl, (C 1 -C 10)alkoxy, aryl, aryl(C 1 -C 6)alkyl, carbamoyl, (C 1 -C 6) aminoalkyl, (C 1 -C 6) hydroxyalkyl; or alternatively, R 2 and R 3, taken together with the nitrogen atom they are linked to, form a mono-cyclic saturated or partially saturated heterocyclic radical, wherein at least one further ring carbon atom is optionally replaced by N, said heterocyclic radical being optionally in its turn further substituted with one or more (C 1 -C 6) alky groups; or pharmaceutically acceptable salts and solvates thereof. n, q and m are zero or an integer from 1 to 2; R 1 is selected from the group consisting of -H, halogen, -CN, (C 1 -C 6) alkyl, R 2 and R 3, the same or different, are selected from the group consisting of -H, (C 1 -C 6) alkyl, (C 1 -C 6) haloalkyl, (C 1 -C 6) hydroxyalkyl, (C 1 -C 6) aminoalkyl, (C 1 -C 6) alkoxy (C 1 -C 6) alkyl, heteroaryl(C 1 -C 6)alkyl, each of said heteroaryl is further optionally substituted by one or more group selected independently from halogen, -CN, -OH, (C 1 -C 8)alkyl, (C 1 -C 6) haloalkyl, (C 1 -C 10)alkoxy, aryl, aryl(C 1 -C 6)alkyl, carbamoyl, (C 1 -C 6) aminoalkyl, (C 1 -C 6) hydroxyalkyl; or alternatively, R 2 and R 3, taken together with the nitrogen atom they are linked to, form a mono-cyclic saturated or partially saturated heterocyclic radical, wherein at least one further ring carbon atom is optionally replaced by N, said heterocyclic radical being optionally in its turn further substituted with one or more (C 1 -C 6) alky groups; or pharmaceutically acceptable salts and solvates thereof.
A method for producing a glass substrate having a sheet thickness of from 10 to 200 μm, which comprises a forming step of forming a molten glass into a ribbon shape in accordance with a down draw method, an annealing step of annealing the glass ribbon, and a cutting step of cutting the glass ribbon to give the glass substrate, wherein, in the annealing step, an average cooling rate in a temperature range of from the (annealing point + 200 °C) to the (annealing point + 50 °C) is controlled to the range of from 400 to 2,500 °C/min.
A method of controlling inter-vehicle gap(s) (24a-c) in a platoon comprising a lead vehicle and one or more following vehicles (14a-c), wherein the method comprises the steps of: obtaining an indicator of a potential collision threat identified by an autonomous emergency braking system of the lead vehicle, and sending the obtained indicator to the one or more following vehicles, characterized in that: the autonomous emergency braking system of the lead vehicle comprises pre-defined control phases (28a-c), including a first alert phase, a second warning brake phase, and a third full brake phase, the indicator at least partly determines a current control phase of the autonomous emergency braking system, a driver of the lead vehicle is informed using a human machine interface when in the first alert phase, and a speed of the lead vehicle is reduced using an advanced breaking system comprised with the lead vehicle when in the second warning brake phase or the third full brake phase. obtaining an indicator of a potential collision threat identified by an autonomous emergency braking system of the lead vehicle, and sending the obtained indicator to the one or more following vehicles, characterized in that: the autonomous emergency braking system of the lead vehicle comprises pre-defined control phases (28a-c), including a first alert phase, a second warning brake phase, and a third full brake phase, the indicator at least partly determines a current control phase of the autonomous emergency braking system, a driver of the lead vehicle is informed using a human machine interface when in the first alert phase, and a speed of the lead vehicle is reduced using an advanced breaking system comprised with the lead vehicle when in the second warning brake phase or the third full brake phase. the autonomous emergency braking system of the lead vehicle comprises pre-defined control phases (28a-c), including a first alert phase, a second warning brake phase, and a third full brake phase, the indicator at least partly determines a current control phase of the autonomous emergency braking system, a driver of the lead vehicle is informed using a human machine interface when in the first alert phase, and a speed of the lead vehicle is reduced using an advanced breaking system comprised with the lead vehicle when in the second warning brake phase or the third full brake phase.
A method for identifying a therapeutic compound effective to reduce invasiveness of fibroblasts characterized by a highly invasive phenotype obtained from a subject with idiopathic pulmonary fibrosis, comprising a. Purifying a population of the fibroblasts characterized by a highly invasive phenotype by: i. Confirming expression of cell surface markers Krtap2-3high and Patched 1 negative by the invasive fibroblasts by flow cytometry; ii. isolating and establishing single cell clones based on expression of the cell surface markers; iii. Transfecting into IPF fibroblasts one or more mammalian expression pcDNA3-XFP vectors selected from the group of Krtap23-GFP, PODXL-RFP, CD127-CFP and PTCH1-mCherry comprising a promoter of Krtap23, PODXL, CD127, or Patched 1 inserted upstream of the fluorescent protein tag; iv. Selecting positive cells of XFP (fluorescent protein) expression; and v. Determining cell marker expression, matrix production, proliferation, survival, migration and invasive capacity of the transfected cells, b. Contacting the population of fibroblasts characterized by the highly invasive phenotype with a prospective therapeutic compound; and c. Reducing invasiveness of the fibroblasts as measured in an invasiveness assay, with minimal impact on normal lung fibroblasts with a non-invasive phenotype. a. Purifying a population of the fibroblasts characterized by a highly invasive phenotype by: i. Confirming expression of cell surface markers Krtap2-3high and Patched 1 negative by the invasive fibroblasts by flow cytometry; ii. isolating and establishing single cell clones based on expression of the cell surface markers; iii. Transfecting into IPF fibroblasts one or more mammalian expression pcDNA3-XFP vectors selected from the group of Krtap23-GFP, PODXL-RFP, CD127-CFP and PTCH1-mCherry comprising a promoter of Krtap23, PODXL, CD127, or Patched 1 inserted upstream of the fluorescent protein tag; iv. Selecting positive cells of XFP (fluorescent protein) expression; and v. Determining cell marker expression, matrix production, proliferation, survival, migration and invasive capacity of the transfected cells, i. Confirming expression of cell surface markers Krtap2-3high and Patched 1 negative by the invasive fibroblasts by flow cytometry; ii. isolating and establishing single cell clones based on expression of the cell surface markers; iii. Transfecting into IPF fibroblasts one or more mammalian expression pcDNA3-XFP vectors selected from the group of Krtap23-GFP, PODXL-RFP, CD127-CFP and PTCH1-mCherry comprising a promoter of Krtap23, PODXL, CD127, or Patched 1 inserted upstream of the fluorescent protein tag; iv. Selecting positive cells of XFP (fluorescent protein) expression; and v. Determining cell marker expression, matrix production, proliferation, survival, migration and invasive capacity of the transfected cells, b. Contacting the population of fibroblasts characterized by the highly invasive phenotype with a prospective therapeutic compound; and c. Reducing invasiveness of the fibroblasts as measured in an invasiveness assay, with minimal impact on normal lung fibroblasts with a non-invasive phenotype.
A defibrillation electrode pad comprising: an electrode section; and a CPR administration section mechanically coupled to the electrode section; the electrode section and the CPR administration section positioned in the defibrillation electrode pad relative to each other such that the CPR administration section is located above a sternum of an adult subject and the electrode section is located in a position appropriate for the administration of a defibrillation shock to the adult subject when the electrode section and the CPR administration section are both oriented in a first orientation characterized in that the electrode section and the CPR administration section are further positioned such that the CPR administration section is located above a sternum of a pediatric subject and the electrode section is located in a position appropriate for the administration of a defibrillation shock to the pediatric subject when the electrode section and the CPR administration section are both oriented in a second orientation different from the first orientation. an electrode section; and a CPR administration section mechanically coupled to the electrode section; the electrode section and the CPR administration section positioned in the defibrillation electrode pad relative to each other such that the CPR administration section is located above a sternum of an adult subject and the electrode section is located in a position appropriate for the administration of a defibrillation shock to the adult subject when the electrode section and the CPR administration section are both oriented in a first orientation characterized in that the electrode section and the CPR administration section are further positioned such that the CPR administration section is located above a sternum of a pediatric subject and the electrode section is located in a position appropriate for the administration of a defibrillation shock to the pediatric subject when the electrode section and the CPR administration section are both oriented in a second orientation different from the first orientation.
Connection arrangement for connection of an electrical conductor, comprising - a current bar, - a clamping spring which has a clamping limb which can be moved to a clamping position and to an open position, - a conductor connection area formed between a portion of the current bar and of the clamping limb of the clamping spring, - a displaceably arranged guide element which is operatively connected to the clamping limb of the clamping spring, wherein the clamping limb can be held in the open position by means of the guide element, and - a release element which is in engagement with the guide element in the open position of the clamping limb of the clamping spring, wherein the release element, when the conductor to be connected is inserted into the conductor connection area, can be actuated by the conductor in such a way that the release element disengages from the guide element and the guide element can be displaced by a spring force of the clamping limb in such a way that the clamping limb is moved to the clamping position for the purpose of clamping the conductor against the current bar, characterized in that the guide element can be displaced in such a way that a displacement movement of the guide element takes place transversely to an insertion direction of the conductor to be connected into the conductor connection area. - a current bar, - a clamping spring which has a clamping limb which can be moved to a clamping position and to an open position, - a conductor connection area formed between a portion of the current bar and of the clamping limb of the clamping spring, - a displaceably arranged guide element which is operatively connected to the clamping limb of the clamping spring, wherein the clamping limb can be held in the open position by means of the guide element, and - a release element which is in engagement with the guide element in the open position of the clamping limb of the clamping spring, wherein the release element, when the conductor to be connected is inserted into the conductor connection area, can be actuated by the conductor in such a way that the release element disengages from the guide element and the guide element can be displaced by a spring force of the clamping limb in such a way that the clamping limb is moved to the clamping position for the purpose of clamping the conductor against the current bar,
A controller for a vehicle, characterized in comprising: a vehicle yaw moment instruction calculator that is configured to calculate a vehicle yaw moment instruction value on the basis of a lateral jerk of the vehicle; wherein a yaw moment of the vehicle is controlled under a control mode on the basis of the vehicle yaw moment instruction value that generates driving forces or driving torques and/or braking forces or braking torques of wheels of the vehicle; wherein if the vehicle yaw moment instruction value generates the driving forces or the driving torques, the driving forces or driving torques are different between the left and right wheels; and if the vehicle yaw moment instruction value generates the braking forces or the braking torques, the braking forces or the braking torques are different between the left and right wheels; wherein the control mode operates at least in a transit region between a daily region where a lateral slip angle is small and a limit region, wherein the limit region is a region where the lateral slip angle becomes large. wherein a yaw moment of the vehicle is controlled under a control mode on the basis of the vehicle yaw moment instruction value that generates driving forces or driving torques and/or braking forces or braking torques of wheels of the vehicle; wherein if the vehicle yaw moment instruction value generates the driving forces or the driving torques, the driving forces or driving torques are different between the left and right wheels; and if the vehicle yaw moment instruction value generates the braking forces or the braking torques, the braking forces or the braking torques are different between the left and right wheels; wherein the control mode operates at least in a transit region between a daily region where a lateral slip angle is small and a limit region, wherein the limit region is a region where the lateral slip angle becomes large.
Washing machine comprising a suds container arranged in a housing and a drum, which is rotatably mounted within the suds container and driven by a drive motor, for receiving the items of laundry to be treated; - a supply line (23, 26) for feeding fresh water from an external water supply to the suds container; - a valve for controlling or releasing and blocking the water supply through the supply line (23, 26); - a device for dispensing a treatment agent, for example detergent, into the suds container, which device has a storage container for treatment agent, a supply line and a metering pump for conveying the treatment agent through the supply line into the suds container; - a sensor device for detecting the amount of washing liquid in the suds container; - a control device for controlling the valve, the drive motor and the metering pump, the control device being designed and programmed to control the metering pump, and thus the amount of treatment agent to be metered, depending on the detected amount of fresh water fed to the suds container, characterised in that the control device is designed and programmed to activate the valve for a first-phase water inlet and for a second-phase water inlet, to close the valve between the first and the second phase, and to activate the drive motor to rotate the drum. - a supply line (23, 26) for feeding fresh water from an external water supply to the suds container; - a valve for controlling or releasing and blocking the water supply through the supply line (23, 26); - a device for dispensing a treatment agent, for example detergent, into the suds container, which device has a storage container for treatment agent, a supply line and a metering pump for conveying the treatment agent through the supply line into the suds container; - a sensor device for detecting the amount of washing liquid in the suds container; - a control device for controlling the valve, the drive motor and the metering pump,
An inverter unit for a hollow glassware forming machine, the unit comprising: - a supporting structure; - a first and a second pick-and-place arm (3, 4) defining one or more recesses for picking up the glassware and coupled to said supporting structure, so as to rotate about a first axis, and so as to be movable along said first axis with respect to each other between an open position and a closed position; characterized in that it comprises a centering device for adjusting the position of said supporting structure with respect to a base in a direction parallel to said first axis; said centering device comprising a head which can rotate about a second axis and external to said supporting structure so that it can be operated, and a transmission mechanism, which converts the rotary motion of the head into a translational motion of the structure. - a supporting structure; - a first and a second pick-and-place arm (3, 4) defining one or more recesses for picking up the glassware and coupled to said supporting structure, so as to rotate about a first axis, and so as to be movable along said first axis with respect to each other between an open position and a closed position;