A refrigerator comprising: a cabinet; a door configured to open or close the cabinet and including an outer plate defining a front surface of the door and having a plate opening and a door liner defining a rear surface of the door and having liner opening, the plate opening and the liner opening are penetrated in front and rear directions; a transparent panel assembly which is mounted to cover the plate opening and through which an inside of the refrigerator is seen; and a lighting member provided in the door or the cabinet to brighten a rear side of the transparent panel assembly, wherein the transparent panel assembly comprises: a front panel defining an outer appearance of a front surface; a rear panel defining an outer appearance of a rear surface; a spacer disposed between the front panel and the rear panel to define a periphery of the transparent panel assembly and made of a metal material; and a heater mounting part on which a heater is mounted, characterized in that the heater mounting part is disposed on the spacer, wherein a side of the front panel comes into contact with the spacer and is heated when the heater generates heat, wherein the refrigerator further comprises: a support frame mounted on a periphery of the plate opening and configured to support the transparent panel assembly, the support frame comprises: a plate support part configured to support a rear surface of the outer plate; a panel support part configured to support a rear surface of the front panel; and a blocking part provided at an end of the panel support part and configured to prevent foam liquid for forming an insulator from being introduced toward the transparent panel assembly, wherein the blocking part is coupled to the outer spacer through a coupling member. a cabinet; a door configured to open or close the cabinet and including an outer plate defining a front surface of the door and having a plate opening and a door liner defining a rear surface of the door and having liner opening, the plate opening and the liner opening are penetrated in front and rear directions; a transparent panel assembly which is mounted to cover the plate opening and through which an inside of the refrigerator is seen; and a lighting member provided in the door or the cabinet to brighten a rear side of the transparent panel assembly, wherein the transparent panel assembly comprises: a front panel defining an outer appearance of a front surface; a rear panel defining an outer appearance of a rear surface; a spacer disposed between the front panel and the rear panel to define a periphery of the transparent panel assembly and made of a metal material; and a heater mounting part on which a heater is mounted, characterized in that the heater mounting part is disposed on the spacer, wherein a side of the front panel comes into contact with the spacer and is heated when the heater generates heat, wherein the refrigerator further comprises: a support frame mounted on a periphery of the plate opening and configured to support the transparent panel assembly, the support frame comprises: a plate support part configured to support a rear surface of the outer plate; a panel support part configured to support a rear surface of the front panel; and a blocking part provided at an end of the panel support part and configured to prevent foam liquid for forming an insulator from being introduced toward the transparent panel assembly, wherein the blocking part is coupled to the outer spacer through a coupling member. a front panel defining an outer appearance of a front surface; a rear panel defining an outer appearance of a rear surface; a spacer disposed between the front panel and the rear panel to define a periphery of the transparent panel assembly and made of a metal material; and a heater mounting part on which a heater is mounted, characterized in that the heater mounting part is disposed on the spacer, wherein a side of the front panel comes into contact with the spacer and is heated when the heater generates heat, wherein the refrigerator further comprises: a support frame mounted on a periphery of the plate opening and configured to support the transparent panel assembly, the support frame comprises: a plate support part configured to support a rear surface of the outer plate; a panel support part configured to support a rear surface of the front panel; and a blocking part provided at an end of the panel support part and configured to prevent foam liquid for forming an insulator from being introduced toward the transparent panel assembly, wherein the blocking part is coupled to the outer spacer through a coupling member. a support frame mounted on a periphery of the plate opening and configured to support the transparent panel assembly, the support frame comprises: a plate support part configured to support a rear surface of the outer plate; a panel support part configured to support a rear surface of the front panel; and a blocking part provided at an end of the panel support part and configured to prevent foam liquid for forming an insulator from being introduced toward the transparent panel assembly, wherein the blocking part is coupled to the outer spacer through a coupling member.