mhurhangee/ep-ind-claims huggingface dataset:
A heterodimeric antibody consisting of an anti-CD3 scFv-Fc consisting of the amino acid sequence of SEQ ID NO:335, an anti-CD38 light chain consisting of the amino acid sequence of SEQ ID NO:336, and an anti-CD38 heavy chain consisting of the amino acid sequence of SEQ ID NO:377.
An airbrush apparatus for producing a spray pattern from the nib of a pen such as a felt-tipped pen, the apparatus comprising: (i) a pen having a nib; (ii) means for generating a flow of air; (iii) a conical airflow nozzle (22, 24) having a wider end connected to the air flow generating means and a narrower end through which air is discharged from the nozzle through an aperture onto the nib of the pen; and (iv) support means arranged to releasably hold the pen; the apparatus being characterised in that the narrower end of the airflow nozzle is formed as an inclined surface whose slope lies generally parallel to the longitudinal axis of the nib to provide a space into which one side of the nib of the pen is received. (i) a pen having a nib; (ii) means for generating a flow of air; (iii) a conical airflow nozzle (22, 24) having a wider end connected to the air flow generating means and a narrower end through which air is discharged from the nozzle through an aperture onto the nib of the pen; and (iv) support means arranged to releasably hold the pen;
Fixing device for webbing and/or planar securing means (4, 5) for securing a load on a loading surface of transporting vehicles, with at least one hook for engagement in an opening of a transporting wall (2, 3), and with a connecting element for connecting one or more securing means (4, 5), wherein the connecting element is releasably connected to the hook, wherein further the connecting element is equipped with a hinge extension, which releasably engages in an extension holder on an arresting element bearing the hook, and wherein when connected to each other, the hinge extension and the extension recess comprises flush drilled holes for a hinge bolt releasably engaging therein, characterised in that the hinge bolt is equipped with at least one spring-loaded catch element and with a handle, wherein the handle is a grip or an eye, which an operator grasps with, for example, one of more fingers in order to remove the hinge bolt from the flush drilled holes or to insert it into them again. the connecting element is releasably connected to the hook, wherein further the connecting element is equipped with a hinge extension, which releasably engages in an extension holder on an arresting element bearing the hook, and wherein when connected to each other, the hinge extension and the extension recess comprises flush drilled holes for a hinge bolt releasably engaging therein, characterised in that the hinge bolt is equipped with at least one spring-loaded catch element and with a handle, wherein the handle is a grip or an eye, which an operator grasps with, for example, one of more fingers in order to remove the hinge bolt from the flush drilled holes or to insert it into them again.
An automotive frame part that is an A-pillar-lower part including an outer panel and an inner panel made of metal, the outer panel having approximately a T-shape in planar view and a cross section intersecting a portion corresponding to a horizontal side and a vertical side of the T-shape is a hat-shaped cross section including a top portion, a side wall portion, and a flange portion, the inner panel being connected to the flange portion of the outer panel and forming a closed cross section with the outer panel, the automotive frame part comprising: plastic stiffening members that each have one end connected to an inner surface of the outer panel and another end connected to an inner surface of the inner panel in a space formed between the outer panel and the inner panel, characterized in that the shape and the disposition of the stiffening members are set based on an analysis result from a shape optimization analysis method and each of the stiffening members has a columnar shape or a columnar shape with both end parts bulging. plastic stiffening members that each have one end connected to an inner surface of the outer panel and another end connected to an inner surface of the inner panel in a space formed between the outer panel and the inner panel, characterized in that the shape and the disposition of the stiffening members are set based on an analysis result from a shape optimization analysis method and each of the stiffening members has a columnar shape or a columnar shape with both end parts bulging.
A catheter (1, 6) comprising: an inner layer that is a long hollow tubular body, a tubular braid (11, 21, 31) that covers an outer periphery of the inner layer, and a tubular outer layer (19, 29, 39) that covers an outer periphery of the braid (11, 21, 31), wherein the braid (11, 21, 31) is folded back at least at one of the longitudinal ends of the inner layer to form a multiple folded part (10, 20, 30) so that a tip end (17, 27, 37) of the braid (11, 21, 31) is in contact with the inner layer and is arranged in a lowest layer of the folded part (10, 20, 30). an inner layer that is a long hollow tubular body, a tubular braid (11, 21, 31) that covers an outer periphery of the inner layer, and a tubular outer layer (19, 29, 39) that covers an outer periphery of the braid (11, 21, 31), wherein
Safety assembly for preventing needle stick injury with a needle having a proximal end fixed to a tip of a medical container and a pointed distal end, the safety assembly comprising: - an attachment ring configured to be fixed to the tip of the container; - a safety device (60, 70) configured to cover at least the distal end of the needle, the safety device being attached to the attachment ring; wherein: - the attachment ring comprises an inner ring and an outer ring configured to be snapped onto each other, - the inner ring comprises an inner recess configured for applying glue between the inner ring and the tip, - the inner ring and outer ring comprise mutually engaging elements preventing any rotation of the outer ring relative to the inner ring, characterised in that, - the mutually engaging elements comprise at least one male element and at least one female element (222, 216) complementary to said male element, said male and female elements being configured such that when the outer ring is snapped onto the inner ring, the male element engages the female element (222, 216), and - the male and female elements have at least two inclined contact surfaces allowing the outer ring to slide relative to the inner ring under a combined pivotal and axial movement until the at least one male element engages a respective female element. - an attachment ring configured to be fixed to the tip of the container; - a safety device (60, 70) configured to cover at least the distal end of the needle, the safety device being attached to the attachment ring; - the attachment ring comprises an inner ring and an outer ring configured to be snapped onto each other, - the inner ring comprises an inner recess configured for applying glue between the inner ring and the tip, - the inner ring and outer ring comprise mutually engaging elements preventing any rotation of the outer ring relative to the inner ring, characterised in that, - the mutually engaging elements comprise at least one male element and at least one female element (222, 216) complementary to said male element, said male and female elements being configured such that when the outer ring is snapped onto the inner ring, the male element engages the female element (222, 216), and - the male and female elements have at least two inclined contact surfaces allowing the outer ring to slide relative to the inner ring under a combined pivotal and axial movement until the at least one male element engages a respective female element.
An automotive plug ignition coil core system, comprising: a first core formed of a plurality of stacked laminations of electrical steel and each of which comprises a segmented lamination strip folded around in a closed loop shape; each segmented lamination strip having first, second, third, and fourth segments, and a hinge web being provided between the first and second, second and third, and third and fourth segments; and a grain direction of the electrical steel running lengthwise in each of said first, second, third, and fourth segments. a first core formed of a plurality of stacked laminations of electrical steel and each of which comprises a segmented lamination strip folded around in a closed loop shape; each segmented lamination strip having first, second, third, and fourth segments, and a hinge web being provided between the first and second, second and third, and third and fourth segments; and a grain direction of the electrical steel running lengthwise in each of said first, second, third, and fourth segments.
A deployment system comprising: a mount (24, 26) configured to receive a device (14, 16) to be deployed; a hub assembly (34, 36) that includes: an outer tube having a cam slot, an inner tube within the outer tube, wherein the inner tube is connected to the mount (24, 26), and a tension rod located along a central axis (44, 46) of the hub assembly (34, 36), wherein the tension rod mechanically engages the inner tube and the mount (24, 26) and has opposite first and second threaded ends (122, 124), wherein the first threaded end has a pair of nuts (132, 134) thereon that bear on opposite major surfaces of a platform that is within the inner tube, and the second threaded end threadedly engages the mount (24, 26); and an actuator configured to rotate the mount (24, 26) relative to the outer tube; wherein when the actuator causes the mount (24, 26) to rotate relative to the outer tube, a follower engaging the cam slot causes the mount to move both axially and rotationally relative to the outer tube, wherein the inner tube moves along with the mount. a mount (24, 26) configured to receive a device (14, 16) to be deployed; a hub assembly (34, 36) that includes: an outer tube having a cam slot, an inner tube within the outer tube, wherein the inner tube is connected to the mount (24, 26), and a tension rod located along a central axis (44, 46) of the hub assembly (34, 36), wherein the tension rod mechanically engages the inner tube and the mount (24, 26) and has opposite first and second threaded ends (122, 124), wherein the first threaded end has a pair of nuts (132, 134) thereon that bear on opposite major surfaces of a platform that is within the inner tube, and the second threaded end threadedly engages the mount (24, 26); and an outer tube having a cam slot, an inner tube within the outer tube, wherein the inner tube is connected to the mount (24, 26), and a tension rod located along a central axis (44, 46) of the hub assembly (34, 36), wherein the tension rod mechanically engages the inner tube and the mount (24, 26) and has opposite first and second threaded ends (122, 124), wherein the first threaded end has a pair of nuts (132, 134) thereon that bear on opposite major surfaces of a platform that is within the inner tube, and the second threaded end threadedly engages the mount (24, 26); and wherein the first threaded end has a pair of nuts (132, 134) thereon that bear on opposite major surfaces of a platform that is within the inner tube, and the second threaded end threadedly engages the mount (24, 26); and an actuator configured to rotate the mount (24, 26) relative to the outer tube; wherein when the actuator causes the mount (24, 26) to rotate relative to the outer tube, a follower engaging the cam slot causes the mount to move both axially and rotationally relative to the outer tube, wherein the inner tube moves along with the mount.
A material for forming an organic film, comprising: a compound shown by the following general formula; and an organic solvent, wherein R 1 represents one of the following formulae, R 2 represents a nitro group, a halogen atom, a hydroxy group, an alkyloxy group having 1 to 4 carbon atoms, an alkynyloxy group having 2 to 4 carbon atoms, an alkenyloxy group having 2 to 4 carbon atoms, a linear, branched, or cyclic alkyl group having 1 to 6 carbon atoms, a trifluoromethyl group, or a trifluoromethyloxy group, "n" represents 0 or 1, "m" represents an integer of 1 to 3, "p" represents 0 or 1, "l" represents an integer of 0 to 2, and W represents a divalent organic group having 2 to 40 carbon atoms.
A method for waterproofing a gypsum-based product formed from a plaster-based composition, characterized by adding at least one compound comprising a polysiloxane and at least one compound comprising a pregelified starch to said composition, wherein said compound comprising a polysiloxane is present in the composition in a ratio of 0.01 % to 1.5% by weight to plaster powder.
Subscriber station (10; 30) for a bus system, having a transmission/reception device for transmitting or receiving a message (45; 46; 47) to/from at least one further subscriber station of the bus system via the bus system, in which bus system, at least intermittently, exclusive collision-free access by a subscriber station (10,20,30) to a bus of the bus system is ensured, and a communication control device for creating the message (45; 46; 47) to be transmitted by the transmission/reception device or for reading the message (45; 46; 47) received by the transmission/reception device according to a predetermined communication protocol for the bus system, and a delay unit connected between the communication control device and the transmission/reception device in order to delay a transmission signal transmitted from the communication control device to the transmission/reception device and a received signal received by the transmission/reception device.
A process for making a nanoporous substrate comprising the steps of: (a) grafting onto a backbone of a reactive organic resin, a thermolabile functionality by reacting hydrogen active groups of the reactive organic resin with a compound containing thermolabile group, wherein the organic resin is an epoxy resin; (b) preparing a composition by blending the reactive organic resin containing thermolabile groups grafted thereto from step (a) with at least a curing agent; and (c) thermally degrading the thermolabile groups grafted on the organic resin such as to produce a nanoporous substrate. (a) grafting onto a backbone of a reactive organic resin, a thermolabile functionality by reacting hydrogen active groups of the reactive organic resin with a compound containing thermolabile group, wherein the organic resin is an epoxy resin; (b) preparing a composition by blending the reactive organic resin containing thermolabile groups grafted thereto from step (a) with at least a curing agent; and (c) thermally degrading the thermolabile groups grafted on the organic resin such as to produce a nanoporous substrate.
A compound, an isomer thereof and a pharmaceutically acceptable salt or a pharmaceutically acceptable solvate thereof, wherein, the compound is one selected from the following compounds: Cpd. No. Name Structure 2S N-(4-((7-(dimethylamino)-1,6-napht hyridin-4-yl)oxy)-3-fluorophenyl)-N -(4-fluorophenyl)cyclopropyl-1,1-di carboxamide 7S N-(3-fluoro-4-((7-(2-morpholinoeth oxy)-1,6-naphthyridin-4-yl)oxy)phe nyl)-N-(4-fluorophenyl)cyclopropyl-1,1-dicarboxamide 8S N-(3-fluoro-4-((7-(2-morpholinopro poxy)-1,6-naphthyridin-4-yl)oxy)ph enyl)-N-(4-fluorophenyl)cyclopropy l-1,1-dicarboxamide 9S N-(3-fluoro-4-((7-((1-methylpiperidi n-4-yl)methoxy)-1,6-naphthyridin-4 -yl)oxy)phenyl)-N-(4-fluorophenyl)c yclopropyl-1,1-dicarboxamide 15S N-(3-fluoro-4-((7-(2-morpholinoeth oxy)-1,6-naphthyridin-4-yl)oxy)phe nyl)-1-(4-fluorophenyl)-2-oxo-1,2-di hydropyridine-3-carboxamide 20S N-(3-fluoro-4-((7-(2-morpholinoeth oxy)-1,6-naphthyridin-4-yl)oxy)phe nyl)-4-oxo-5-phenyl-1,4-dihydropyri dine-3-carboxamide 22S N-(3-fluoro-4-((7-(2-morpholinoeth oxy)-1,6-naphthyridin-4-yl)oxy)phe nyl)-5-(4-fluorophenyl)-4-oxo-1,4-di hydropyridine-3-carboxamide 37S N-(3-fluoro-4-((7-(2-(3-oxomorpholi no)ethoxy)-1,6-naphthyridin-4-yl)o xy)phenyl)-N-(4-fluorophenyl)cyclo propyl-1,1-dicarboxamide 38S N-(3-fluoro-4-((7-(1-methyl-1H-pyr azol-4-yl)-1,6-naphthyridin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopr opyl-1,1-dicarboxamide 39S N-(4-((7-(1H-pyrazol-4-yl)-1,6-naph thyridin-4-yl)oxy)-3-fluorophenyl)-N-(4-fluorophenyl)cyclopropyl-1,1-dicarboxamide 40S N-(3-fluoro-4-((7-(1-(methylsulfonyl)-1H-pyrazol-4-yl)-1,6-naphthyridin-4-yl)oxy)phenyl)-N-(4-fluorophenyl) cyclopropyl-1,1-dicarboxamide 41S N-(3-fluoro-4-((7-(1-isopropyl-1H-p yrazol-4-yl)-1,6-naphthyridin-4-yl)o xy)phenyl)-N-(4-fluorophenyl)cyclo propyl-1,1-dicarboxamide 42S N-(3-fluoro-4-((7-(1-(piperidin-4-yl) -1H-pyrazol-4-yl)-1,6-naphthyridin-4-yl)oxy)phenyl)-N-(4-fluorophenyl) cyclopropyl-1,1-dicarboxamide 47S N-(3-fluoro-4-((7-(pyrimidin-5-yl)-1, 6-naphthyridin-4-yl)oxy)phenyl)-N-( 4-fluorophenyl)cyclopropyl-1,1-dica rboxamide 49S N-(3-fluoro-4-((7-(3,4-difluorophen yl)-1,6-naphthyridin-4-yl)oxy)pheny l)-N-(4-fluorophenyl)cyclopropyl-1, 1-dicarboxamide 54S N-(3-fluoro-4-((7-(1-methyl-1H-pyr azol-4-yl)-1,6-naphthyridin-4-yl)oxy)phenyl)-5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxamide
Method for conveying and for changing an orientation of a piece product with the steps: feeding the product onto a product support of a conveying and rotating unit in a predetermined first orientation; changing the orientation of the product from the first orientation to a second orientation by means of a first driver of the conveying and rotating unit, which first driver is moved in a predetermined conveying direction, by the first driver abutting against the product eccentrically with respect to a direction perpendicular to the conveying direction and thereby introducing a rotational impulse into the product; and conveying the product in the second orientation in the conveying direction by abutting of a second driver, which is moved in the conveying direction, against the product at at least two points lying on opposite sides, with respect to a center of the product, in the direction perpendicular to the conveying direction. feeding the product onto a product support of a conveying and rotating unit in a predetermined first orientation; changing the orientation of the product from the first orientation to a second orientation by means of a first driver of the conveying and rotating unit, which first driver is moved in a predetermined conveying direction, by the first driver abutting against the product eccentrically with respect to a direction perpendicular to the conveying direction and thereby introducing a rotational impulse into the product; and conveying the product in the second orientation in the conveying direction by abutting of a second driver, which is moved in the conveying direction, against the product at at least two points lying on opposite sides, with respect to a center of the product, in the direction perpendicular to the conveying direction.
A cartridge configured to be removably attachable to an apparatus body of an image forming apparatus, the cartridge comprising: a rotation member (62, 66) comprising a coupling (21, 70) configured to be coupleable to a driving shaft provided in the apparatus body and to rotate by receiving a driving force from the driving shaft; a frame body; and a bearing member attached to the frame body and configured to rotatably support the rotation member (62, 66), characterized in that: the bearing member has an engaged portion that is positioned on one end side of the cartridge in a direction of a rotational axis of the rotation member (62, 66) and configured to engage with an engaging portion provided in the apparatus body, such that an engagement state between the engaged portion and the engaging portion is maintained until at least the coupling (21, 70) is coupled to the driving shaft in a process of attaching the cartridge to the apparatus body, and such that a movement of the bearing member towards, at least, the other end side of the cartridge in the direction of the rotational axis is restricted when the engaged portion and the engaging portion are put into the engagement state. a rotation member (62, 66) comprising a coupling (21, 70) configured to be coupleable to a driving shaft provided in the apparatus body and to rotate by receiving a driving force from the driving shaft; a frame body; and a bearing member attached to the frame body and configured to rotatably support the rotation member (62, 66), characterized in that: the bearing member has an engaged portion that is positioned on one end side of the cartridge in a direction of a rotational axis of the rotation member (62, 66) and configured to engage with an engaging portion provided in the apparatus body, such that an engagement state between the engaged portion and the engaging portion is maintained until at least the coupling (21, 70) is coupled to the driving shaft in a process of attaching the cartridge to the apparatus body, and such that a movement of the bearing member towards, at least, the other end side of the cartridge in the direction of the rotational axis is restricted when the engaged portion and the engaging portion are put into the engagement state. the bearing member has an engaged portion that is positioned on one end side of the cartridge in a direction of a rotational axis of the rotation member (62, 66) and configured to engage with an engaging portion provided in the apparatus body, such that an engagement state between the engaged portion and the engaging portion is maintained until at least the coupling (21, 70) is coupled to the driving shaft in a process of attaching the cartridge to the apparatus body, and such that a movement of the bearing member towards, at least, the other end side of the cartridge in the direction of the rotational axis is restricted when the engaged portion and the engaging portion are put into the engagement state.
An aerosol delivery device comprising: a mouthpiece end; a primary air channel extending from an air inlet of the aerosol delivery device to an opening in the mouthpiece end; an aerosol generation chamber in fluid communication with the mouthpiece end via a portion of the primary air channel, wherein the aerosol generation chamber comprises an aerosol source for generating an aerosol from a source material for inhalation by a user through the mouthpiece end during use; and a sensor for detecting when a user inhales on the mouthpiece end, wherein the sensor is in fluid communication with the mouthpiece end via a secondary air channel, and wherein the sensor is located further from the mouthpiece end than the aerosol source, and characterised in that the secondary air channel bypasses the aerosol generation chamber such that the secondary air channel is completely separate from the primary air channel, or is separate from the primary air channel up to a location in the primary air channel which is downstream of the aerosol generation chamber. a mouthpiece end; a primary air channel extending from an air inlet of the aerosol delivery device to an opening in the mouthpiece end; an aerosol generation chamber in fluid communication with the mouthpiece end via a portion of the primary air channel, wherein the aerosol generation chamber comprises an aerosol source for generating an aerosol from a source material for inhalation by a user through the mouthpiece end during use; and a sensor for detecting when a user inhales on the mouthpiece end, wherein the sensor is in fluid communication with the mouthpiece end via a secondary air channel, and wherein the sensor is located further from the mouthpiece end than the aerosol source, and characterised in that the secondary air channel bypasses the aerosol generation chamber such that the secondary air channel is completely separate from the primary air channel, or is separate from the primary air channel up to a location in the primary air channel which is downstream of the aerosol generation chamber.