A compound of Formula I: wherein R 1 is: H; C 1 -C 6 alkyl optionally substituted with 1-3 R 4; C 1 -C 6 alkenyl optionally substituted with 1-3 R 4; C 3 -C 6 alkynyl optionally substituted with 1-3 R 4; phenyl, or benzyl wherein each of the phenyl or the benzyl may be optionally substituted with 1-3 R 5, or with a 5- or 6-membered saturated or unsaturated ring system, or with a 5-6 fused ring system, or with a 6-6 fused ring system each containing 1-3 heteroatoms wherein each ring may be optionally substituted with 1-3 R 5, biphenyl or naphthyl optionally substituted with 1-3 R 5; -(CHR 6) m OR 7; -C(=O)R 8; -C(=S)R 8; -C(=O)OR 8; -C(=S)OR 8; -(CHR 6) m N(R 9)R 10; -C(=O)N(R 9)R 10; or -C(=S)N(R 9)R 10; wherein m is an integer 1-3; R 2 is H or C 1 -C 6 alkyl optionally substituted with R 4; alternatively R 1 and R 2 may be taken together to form =CR 11 N(R 12)R 13; R 3 is -C(=O)N(R 9)R 10 or -C(=S)N(R 9)R 10; R 4 is independently halogen, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 4 alkylthio, C 1 -C 4 haloalkylthio, halothio, amino, C 1 -C 3 alkylamino, C 2 -C 6 alkoxycarbonyl, C 2 -C 6 alkylcarbonyl, C 2 -C 6 alkylaminocarbonyl, hydroxyl, or C 3 -C 6 trialkylsilyl; R 5 is independently halogen, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, halothio, amino, C 1 -C 6 alkylamino, C 2 -C 6 dialkylamino, C 2 -C 6 alkoxycarbonyl, or C 2 -C 6 alkylcarbonyl, nitro, hydroxyl, or cyano; R 6 is H, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, benzyl or phenyl wherein each of the benzyl or phenyl may be optionally substituted with 1-3 R 5; R 7 is H, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 3 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyalkyl, C 2 -C 6 alkylcarbonyl, phenyl, or benzyl wherein each of the phenyl, or the benzyl may be optionally substituted with 1-3 R 5, or with a 5- or 6-membered saturated or unsaturated ring system, or with a 5-6 fused ring system, or with a 6-6 fused ring system each containing 1-3 heteroatoms wherein each ring may be optionally substituted with 1-3 R 5, biphenyl or naphthyl optionally substituted with 1-3 R 5; R 8 is H, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 3 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyalkyl, phenyl or benzyl wherein each of the phenyl or the benzyl may be optionally substituted with 1-3 R 5, or with a 5- or 6-membered saturated or unsaturated ring system, or with a 5-6 fused ring system, or with a 6-6 fused ring system each containing 1-3 heteroatoms wherein each ring may be optionally substituted with 1-3 R 5, biphenyl or naphthyl optionally substituted with 1-3 R 5; R 9 is H, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyalkyl, C 1 -C 6 alkylalkoxycarbonyl, C 2 -C 6 alkylcarbonyl,-(CH 2) m SCH 3, phenyl or benzyl wherein each of the phenyl or the benzyl may be optionally substituted with 1-3 R 5, or with a 5- or 6-membered saturated or unsaturated ring system, or with a 5-6 fused ring system, or with a 6-6 fused ring system each containing 1-3 heteroatoms wherein each ring may be optionally substituted with 1-3 R 5, biphenyl or naphthyl optionally substituted with 1-3 R 5; R 10 is H, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxyalkyl, C 2 -C 6 alkylcarbonyl, or benzyl, wherein the benzyl may be optionally substituted with 1-3 R 5; alternatively R 9 and R 10 may be taken together to form a 5- or 6-membered saturated or unsaturated ring containing 1-3 heteroatoms wherein each ring may be optionally substituted with 1-3 R 5; R 11 is H or C 1 -C 4 alkyl; R 12 is H, cyano, hydroxyl, C 1 -C 4 alkyl, C 1 -C 6 alkoxy, C 2 -C 6 alkylcarbonyl, phenyl or benzyl wherein each of the phenyl or the benzyl may be optionally substituted with 1-3 R 5; or with a 5- or 6-membered saturated or unsaturated ring system, or with a 5-6 fused ring system, or with a 6-6 fused ring system each containing 1-3 heteroatoms wherein each ring may be optionally substituted with 1-3 R 5, biphenyl or naphthyl optionally substituted with 1-3 R 5; alternatively R 11 and R 12 may be taken together to form a 5- or 6- membered saturated or unsaturated ring containing 1-3 heteroatoms wherein each ring may be optionally substituted with 1-3 R 5; R 13 is H, C 1 -C 4 alkyl, C 1 -C 6 alkoxy, C 2 -C 6 alkylcarbonyl, phenyl or benzyl wherein each of the phenyl or the benzyl may be optionally substituted with 1-3 R 5; and alternatively R 12 and R 13 may be taken together to form a 5- or 6- membered saturated or unsaturated ring containing 1-3 heteroatoms wherein each ring may be optionally substituted with 1-3 R 5. H; C 1 -C 6 alkyl optionally substituted with 1-3 R 4; C 1 -C 6 alkenyl optionally substituted with 1-3 R 4; C 3 -C 6 alkynyl optionally substituted with 1-3 R 4; phenyl, or benzyl wherein each of the phenyl or the benzyl may be optionally substituted with 1-3 R 5, or with a 5- or 6-membered saturated or unsaturated ring system, or with a 5-6 fused ring system, or with a 6-6 fused ring system each containing 1-3 heteroatoms wherein each ring may be optionally substituted with 1-3 R 5, biphenyl or naphthyl optionally substituted with 1-3 R 5; -(CHR 6) m OR 7; -C(=O)R 8; -C(=S)R 8; -C(=O)OR 8; -C(=S)OR 8; -(CHR 6) m N(R 9)R 10; -C(=O)N(R 9)R 10; or -C(=S)N(R 9)R 10;