A compound of formula: wherein X represents -NH-, -O- or a bond; Y represents (C 1 -C 4)alkandiyl; Z represents O or S; n-represents 0 or 1; R 1 represents • (C 4 -C 6)alkyl; • (C 1 -C 4)alkyl which is mono-substituted with (C 3 -C 6)cycloalkyl, (C 1 -C 4)alkoxy, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted heterocyclyl, optionally substituted aryloxy, optionally substituted heteroaryloxy, optionally substituted aryl-(C 1 -C 2)alkoxy, optionally substituted heteroaryl-(C 1 -C 2)alkoxy, optionally substituted heteroarylsulfanyl or -NR 8 R 9; • (C 2 -C 4)alkenyl which is mono-substituted with optionally substituted aryl; • (C 2 -C 4)alkynyl which is mono-substituted with optionally substituted aryl; • (C 3 -C 6)cycloalkyl which is mono- or di-substituted with (C 1 -C 4)alkyl, mono-substituted with (C 1 -C 4)alkoxy, mono-substituted with optionally substituted aryl or mono-substituted with optionally substituted heteroaryl; • optionally substituted aryl; or • a 10-membered partially unsaturated ring system; R 2 represents hydrogen, (C 1 -C 4)alkyl, (C 1 -C 4)alkoxy, (C 1 -C 4)fluoroalkyl, halogen, (C 1 -C 4)alkylsulfonyl, phenylsulfonyl or (C 1 -C 4)alkylsulfonylamino; R 3 represents hydrogen, (C 1 -C 4)alkoxy or halogen; R 4 represents hydrogen, (C 1 -C 4)alkoxy, halogen, (C 1 -C 4)alkylsulfonyl, optionally substituted aryl or optionally substituted heteroaryl; R 5 represents hydrogen, (C 1 -C 4)alkyl, (C 1 -C 4)alkoxy, (C 1 -C 4)fluoroalkyl, halogen, cyano, -CONH 2, optionally substituted aryl, optionally substituted heteroaryl, (C 1 -C 4)alkylsulfonyl, phenylsulfonyl or dimethylamino-sulfonyl; and R 6 represents hydrogen or halogen; or R 5 and R 6 together form a methylendioxy-group; R 7 represents hydrogen or methyl; R 8 represents hydrogen or methyl; R 9 represents optionally substituted aryl, optionally substituted arylsulfonyl or optionally substituted heteroarylsulfonyl; and R 10 represents -C OH, -C NH-CN, -C NH-OH, -C NH-S 2 CF 3 or optionally substituted heteroaryl; with the proviso that R 1 is different from optionally substituted aryl if X represents -NH- or a bond; or a salt of such a compound. X represents -NH-, -O- or a bond; Y represents (C 1 -C 4)alkandiyl; Z represents O or S; n-represents 0 or 1; R 1 represents • (C 4 -C 6)alkyl; • (C 1 -C 4)alkyl which is mono-substituted with (C 3 -C 6)cycloalkyl, (C 1 -C 4)alkoxy, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted heterocyclyl, optionally substituted aryloxy, optionally substituted heteroaryloxy, optionally substituted aryl-(C 1 -C 2)alkoxy, optionally substituted heteroaryl-(C 1 -C 2)alkoxy, optionally substituted heteroarylsulfanyl or -NR 8 R 9; • (C 2 -C 4)alkenyl which is mono-substituted with optionally substituted aryl; • (C 2 -C 4)alkynyl which is mono-substituted with optionally substituted aryl; • (C 3 -C 6)cycloalkyl which is mono- or di-substituted with (C 1 -C 4)alkyl, mono-substituted with (C 1 -C 4)alkoxy, mono-substituted with optionally substituted aryl or mono-substituted with optionally substituted heteroaryl; • optionally substituted aryl; or • a 10-membered partially unsaturated ring system; • (C 4 -C 6)alkyl; • (C 1 -C 4)alkyl which is mono-substituted with (C 3 -C 6)cycloalkyl, (C 1 -C 4)alkoxy, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted heterocyclyl, optionally substituted aryloxy, optionally substituted heteroaryloxy, optionally substituted aryl-(C 1 -C 2)alkoxy, optionally substituted heteroaryl-(C 1 -C 2)alkoxy, optionally substituted heteroarylsulfanyl or -NR 8 R 9; • (C 2 -C 4)alkenyl which is mono-substituted with optionally substituted aryl; • (C 2 -C 4)alkynyl which is mono-substituted with optionally substituted aryl; • (C 3 -C 6)cycloalkyl which is mono- or di-substituted with (C 1 -C 4)alkyl, mono-substituted with (C 1 -C 4)alkoxy, mono-substituted with optionally substituted aryl or mono-substituted with optionally substituted heteroaryl; • optionally substituted aryl; or • a 10-membered partially unsaturated ring system; R 2 represents hydrogen, (C 1 -C 4)alkyl, (C 1 -C 4)alkoxy, (C 1 -C 4)fluoroalkyl, halogen, (C 1 -C 4)alkylsulfonyl, phenylsulfonyl or (C 1 -C 4)alkylsulfonylamino; R 3 represents hydrogen, (C 1 -C 4)alkoxy or halogen; R 4 represents hydrogen, (C 1 -C 4)alkoxy, halogen, (C 1 -C 4)alkylsulfonyl, optionally substituted aryl or optionally substituted heteroaryl; R 5 represents hydrogen, (C 1 -C 4)alkyl, (C 1 -C 4)alkoxy, (C 1 -C 4)fluoroalkyl, halogen, cyano, -CONH 2, optionally substituted aryl, optionally substituted heteroaryl, (C 1 -C 4)alkylsulfonyl, phenylsulfonyl or dimethylamino-sulfonyl; and R 6 represents hydrogen or halogen; or R 5 and R 6 together form a methylendioxy-group; R 7 represents hydrogen or methyl; R 8 represents hydrogen or methyl; R 9 represents optionally substituted aryl, optionally substituted arylsulfonyl or optionally substituted heteroarylsulfonyl; and R 10 represents -C OH, -C NH-CN, -C NH-OH, -C NH-S 2 CF 3 or optionally substituted heteroaryl; with the proviso that R 1 is different from optionally substituted aryl if X represents -NH- or a bond; or a salt of such a compound.