An intelligent oral appliance comprising: a maxillary appliance configured to be releasably secured to an upper dentition; a mandibular appliance configured to be releasably secured to a lower dentition; characterized by at least one electromagnetic clamp (106,108) coupled between the maxillary or mandibular appliances and configured to operate according to (i) an engaged clamping action in response to energization of the respective at least one electromagnetic clamp (106,108) and (ii) a disengaged clamping action in response to de-energization of the respective at least one electromagnetic clamp (106,108); a first sensor configured to detect at least one of a body position, a body orientation, a head position, a head orientation, or any combination of body and head positions or orientations; a second sensor configured to detect at least one of (i) a characteristic of sleep disordered breathing, (ii) a snoring intensity, or (iii) any combination thereof; a timer configured to provide one or more preset time intervals; and a controller configured to control an activation and a deactivation of the at least one electromagnetic clamp (106,108) between the engaged clamping action and the disengaged clamping action, respectively, (i) to activate the at least one electromagnetic clamp (106,108) and electromagnetically lock the maxillary appliance and mandibular appliance together for one or more air flow prevention cycles in response to (i)(a) an initial powering ON of the intelligent oral appliance or (i)(b) detection of an engagement triggering event and (ii) to de-activate the at least one electromagnetic clamp (106,108) and unlock the maxillary appliance from the mandibular appliance, respectively, for one or more periodic relaxation cycles in response to detection of a disengagement triggering event. a maxillary appliance configured to be releasably secured to an upper dentition; a mandibular appliance configured to be releasably secured to a lower dentition; characterized by at least one electromagnetic clamp (106,108) coupled between the maxillary or mandibular appliances and configured to operate according to (i) an engaged clamping action in response to energization of the respective at least one electromagnetic clamp (106,108) and (ii) a disengaged clamping action in response to de-energization of the respective at least one electromagnetic clamp (106,108); a first sensor configured to detect at least one of a body position, a body orientation, a head position, a head orientation, or any combination of body and head positions or orientations; a second sensor configured to detect at least one of (i) a characteristic of sleep disordered breathing, (ii) a snoring intensity, or (iii) any combination thereof; a timer configured to provide one or more preset time intervals; and a controller configured to control an activation and a deactivation of the at least one electromagnetic clamp (106,108) between the engaged clamping action and the disengaged clamping action, respectively, (i) to activate the at least one electromagnetic clamp (106,108) and electromagnetically lock the maxillary appliance and mandibular appliance together for one or more air flow prevention cycles in response to (i)(a) an initial powering ON of the intelligent oral appliance or (i)(b) detection of an engagement triggering event and (ii) to de-activate the at least one electromagnetic clamp (106,108) and unlock the maxillary appliance from the mandibular appliance, respectively, for one or more periodic relaxation cycles in response to detection of a disengagement triggering event. (i) to activate the at least one electromagnetic clamp (106,108) and electromagnetically lock the maxillary appliance and mandibular appliance together for one or more air flow prevention cycles in response to (i)(a) an initial powering ON of the intelligent oral appliance or (i)(b) detection of an engagement triggering event and (ii) to de-activate the at least one electromagnetic clamp (106,108) and unlock the maxillary appliance from the mandibular appliance, respectively, for one or more periodic relaxation cycles in response to detection of a disengagement triggering event.