mhurhangee/ep-ind-claims huggingface dataset:
Alicyclic derivatives of N,N'-substituted 3,7-diazabicyclo[3.3.1]nonanes of general formula 1 or a pharmacologically acceptable salt thereof: wherein: E is a carbonyl group; R 1 is H, C 1 -C 6 alkyl or C 1 -C 10 alkoxy; R 2 is selected from the group consisting of general formulae ( 1.1a), ( 1.2a), ( 1.3a), ( 1.4a): wherein: L is -C(HR 15)- or a carbonyl group; R 15 is H or C 1 -C 6 alkyl; M is -NH- or a group with the general formula: -NH-(CHR 15) m -, where m = 0-3; R 15 is H or C 1 -C 6 alkyl; or M is a valence bond; R 3, R 3 ', R 4, R 4 ', R 5, R 5 ', R 6, R 6 ', R 7, R 7 ', R 8, R 9, R 10, R 10 ', R 11, R 11 ', R 12, R 12 ', R 13, and R 13 ' may be the same or different and each independently is H, C 1 -C 6 alkyl or C 1 -C 10 alkoxy; R 14 is H, C 1 -C 6 alkyl, C 1 -C 10 alkoxy, halogen, a nitro group, nitrile, acyl or aryl; X is a group with the general formula: where n = 0-3, or X is a valence bond; Z is an atom of oxygen or sulfur. E is a carbonyl group; R 1 is H, C 1 -C 6 alkyl or C 1 -C 10 alkoxy; R 2 is selected from the group consisting of general formulae ( 1.1a), ( 1.2a), ( 1.3a), ( 1.4a): wherein: L is -C(HR 15)- or a carbonyl group; R 15 is H or C 1 -C 6 alkyl; M is -NH- or a group with the general formula: -NH-(CHR 15) m -, where m = 0-3; R 15 is H or C 1 -C 6 alkyl; or M is a valence bond; R 3, R 3 ', R 4, R 4 ', R 5, R 5 ', R 6, R 6 ', R 7, R 7 ', R 8, R 9, R 10, R 10 ', R 11, R 11 ', R 12, R 12 ', R 13, and R 13 ' may be the same or different and each independently is H, C 1 -C 6 alkyl or C 1 -C 10 alkoxy; R 14 is H, C 1 -C 6 alkyl, C 1 -C 10 alkoxy, halogen, a nitro group, nitrile, acyl or aryl; X is a group with the general formula: where n = 0-3, or X is a valence bond; Z is an atom of oxygen or sulfur. L is -C(HR 15)- or a carbonyl group; R 15 is H or C 1 -C 6 alkyl; M is -NH- or a group with the general formula: -NH-(CHR 15) m -, where m = 0-3; R 15 is H or C 1 -C 6 alkyl; or M is a valence bond; R 3, R 3 ', R 4, R 4 ', R 5, R 5 ', R 6, R 6 ', R 7, R 7 ', R 8, R 9, R 10, R 10 ', R 11, R 11 ', R 12, R 12 ', R 13, and R 13 ' may be the same or different and each independently is H, C 1 -C 6 alkyl or C 1 -C 10 alkoxy; R 14 is H, C 1 -C 6 alkyl, C 1 -C 10 alkoxy, halogen, a nitro group, nitrile, acyl or aryl; X is a group with the general formula: where n = 0-3, or X is a valence bond; Z is an atom of oxygen or sulfur. where n = 0-3, or X is a valence bond; Z is an atom of oxygen or sulfur.
An automobile door comprising a glass member, a frame including a resin member joined with the glass member, and one or more resin coating layers disposed on at least one of the glass member and the resin member, wherein, the glass member is a window glass, the resin member includes at least one panel for fastening the window glass, the glass member and the resin member are joined through the one or more resin coating layers, among the one or more resin coating layers, a layer contiguous with the glass member is a modified polyolefin layer formed from a resin composition including a polyolefin, the modified polyolefin layer being at least one type selected from the group consisting of a layer including a reaction product 1 of a maleic anhydride-modified polyolefin, a bifunctional epoxy resin, and a bifunctional phenol compound, a layer including a reaction product 2 of a maleic anhydride-modified polyolefin and a thermoplastic epoxy resin, and a layer including a mixture of a polyolefin and a thermoplastic epoxy resin. the glass member is a window glass, the resin member includes at least one panel for fastening the window glass, the glass member and the resin member are joined through the one or more resin coating layers, among the one or more resin coating layers, a layer contiguous with the glass member is a modified polyolefin layer formed from a resin composition including a polyolefin, the modified polyolefin layer being at least one type selected from the group consisting of a layer including a reaction product 1 of a maleic anhydride-modified polyolefin, a bifunctional epoxy resin, and a bifunctional phenol compound, a layer including a reaction product 2 of a maleic anhydride-modified polyolefin and a thermoplastic epoxy resin, and a layer including a mixture of a polyolefin and a thermoplastic epoxy resin.
A method for the purification of a sialyllactose from other carbohydrates, characterized in that the method comprises the steps of subjecting an aqueous solution containing the sialyllactose and other carbohydrates to two membrane filtration steps using different membranes, wherein - one membrane has a molecular weight cut-off of between about 300 to about 500 Dalton, and - the other membrane has a molecular weight cut-off of between about 600 to about 800 Dalton. - one membrane has a molecular weight cut-off of between about 300 to about 500 Dalton, and - the other membrane has a molecular weight cut-off of between about 600 to about 800 Dalton.
Pneumatic vehicle tyre comprising a carcass, a tread and a breaker belt, which is covered on its radially outer side by a belt bandage with reinforcing elements oriented approximately in the circumferential direction, wherein the term "approximately in the circumferential direction" means an angle of 0° to 5° with reference to the circumferential direction of the tyre, wherein the belt bandage has at least one belt bandage ply, which - when seen in the cross section of the tyre - consists of three portions arranged next to one another, to be specific a central portion and side portions (11, 12) respectively adjoining the central portion, wherein the reinforcing elements of the two side portions (11, 12) are cords of the material PA4.6 and wherein each cord of the belt bandage ply has the construction x2 or the construction x3 and is arranged in a density of 60 to 200 epdm, preferably of 80 to 160 epdm, characterized in that the cords of the central portion are cords of the material PET.
Polymerization reactor system comprising at least one loop reactor and further comprising at least one withdrawal valve, the at least one withdrawal valve comprising a valve cylinder and a valve piston within the valve cylinder, wherein the at least one withdrawal valve is mounted to a wall of a lower horizontal segment of the at least one loop reactor at an angle α of more than 0° and equal to or less than 85°, preferably of equal to or more than 15° to equal to or less than 70°, more preferably of equal to or more than 30° to equal to or less than 55°, most preferably of equal to or more than 40° to equal to or less than 50°, determined from perpendicular to a tangent of the wall at the mounting position in flow direction of a slurry in the at least one loop reactor; and wherein the valve piston of the at least one withdrawal valve comprises a valve plate at an end directed to the at least one loop reactor, the valve plate being shaped according to an inner wall of the at least one loop reactor such that the valve piston is flush with the inner wall of the at least one loop reactor in a closed position of the withdrawal valve; and wherein the valve piston is mounted in the valve cylinder axially rotatable such that the valve piston axially rotates by 180°, when being moved from the closed position to a fully open position. wherein the at least one withdrawal valve is mounted to a wall of a lower horizontal segment of the at least one loop reactor at an angle α of more than 0° and equal to or less than 85°, preferably of equal to or more than 15° to equal to or less than 70°, more preferably of equal to or more than 30° to equal to or less than 55°, most preferably of equal to or more than 40° to equal to or less than 50°, determined from perpendicular to a tangent of the wall at the mounting position in flow direction of a slurry in the at least one loop reactor; and wherein the valve piston of the at least one withdrawal valve comprises a valve plate at an end directed to the at least one loop reactor, the valve plate being shaped according to an inner wall of the at least one loop reactor such that the valve piston is flush with the inner wall of the at least one loop reactor in a closed position of the withdrawal valve; and wherein the valve piston is mounted in the valve cylinder axially rotatable such that the valve piston axially rotates by 180°, when being moved from the closed position to a fully open position.
A drug-coated medical device comprising: a balloon having an inner surface and an outer hydrophobic surface; an adhesion balance layer directly on the outer hydrophobic surface of the balloon, comprising a hydrophilic polymer and/or a hydrophilic compound where the hydrophilic compound has a molecular weight of less than 1,000 Daltons; and a hydrophobic therapeutic layer directly on the adhesion balance layer comprising a therapeutic agent and a pharmaceutically acceptable carrier, wherein: the therapeutic agent is a hydrophobic therapeutic agent with one or more hydrogen-bonding groups and is provided as discrete drug particles in the hydrophobic therapeutic layer; the drug particles have at least one dimension that is less than 25 μm and are uniformly distributed on the surface of the balloon; and the pharmaceutically acceptable carrier is hydrophilic, has a molecular weight of less than 1,000 Daltons, and is selected from one or more of the group consisting of tartaric acid, a sugar, and a sugar alcohol; the amount of carrier to therapeutic agent in the hydrophobic therapeutic layer is from 1:8 to 1:4 wt/wt. a balloon having an inner surface and an outer hydrophobic surface; an adhesion balance layer directly on the outer hydrophobic surface of the balloon, comprising a hydrophilic polymer and/or a hydrophilic compound where the hydrophilic compound has a molecular weight of less than 1,000 Daltons; and a hydrophobic therapeutic layer directly on the adhesion balance layer comprising a therapeutic agent and a pharmaceutically acceptable carrier, wherein: the therapeutic agent is a hydrophobic therapeutic agent with one or more hydrogen-bonding groups and is provided as discrete drug particles in the hydrophobic therapeutic layer; the drug particles have at least one dimension that is less than 25 μm and are uniformly distributed on the surface of the balloon; and the pharmaceutically acceptable carrier is hydrophilic, has a molecular weight of less than 1,000 Daltons, and is selected from one or more of the group consisting of tartaric acid, a sugar, and a sugar alcohol; the amount of carrier to therapeutic agent in the hydrophobic therapeutic layer is from 1:8 to 1:4 wt/wt. the therapeutic agent is a hydrophobic therapeutic agent with one or more hydrogen-bonding groups and is provided as discrete drug particles in the hydrophobic therapeutic layer; the drug particles have at least one dimension that is less than 25 μm and are uniformly distributed on the surface of the balloon; and the pharmaceutically acceptable carrier is hydrophilic, has a molecular weight of less than 1,000 Daltons, and is selected from one or more of the group consisting of tartaric acid, a sugar, and a sugar alcohol; the amount of carrier to therapeutic agent in the hydrophobic therapeutic layer is from 1:8 to 1:4 wt/wt.
A trolley, in particular ward trolley for hospitals, nursing homes and other health care establishments, comprising a bottom part of a cabinet that is movable by means of support rollers, which bottom part serves to receive utensils, and an upper part of the cabinet which can be displaced in the direction of height with respect to the bottom part of the cabinet, characterized in that the bottom part of the cabinet comprises a support frame construction having vertically extending supporting struts (15, 16, 17, 18), wherein respectively one profile element is arranged on each supporting strut (15, 16, 17, 18), which profile element provides a volume space, into which a pin of a support roller is inserted, wherein a plate is provided which covers the supporting frame construction on the side of the support rollers, which plate is arranged between the ends of the profile elements on the side of the support rollers and a roller block of the respective support roller arranged on the profile element.
A polyoxalate containing, as a chief constituent unit, a recurring unit represented by the following formula: wherein, n is a positive number, and A is a divalent organic group, and having a quantity of heat of fusion ΔHm of not less than 60 J/g as measured by the DSC in the first time of elevating the temperature and as calculated by the following formula: ΔHm = ΔHm ′ − ΔHc wherein, ΔHm' is a quantity of heat of fusion (J/g) inclusive of heat of crystallization while the temperature is being elevated, ΔHc is a quantity of heat (J/g) generated by the crystallization, and ΔHm is a quantity of heat of fusion (J/g), permitting the components to be volatilized in an amount of not more than 2.0% by weight when the temperature is elevated up to 200°C as measured by the TGA, and having a 5% weight loss temperature (Td5%) of not higher than 230°C, wherein: ΔHm' is measured from the area of the endothermic peak of fusion and ΔHc is measured from the area of the exothermic peak of crystallization, when the DSC is carried out in nitrogen atmosphere, by elevating the temperature at a rate of 10°C/min and by measuring over a temperature range of 0 to 250°C; and the TGA used to measure the amount of components to be volatilized and the weight loss temperature is carried out in nitrogen atmosphere, by elevating the temperature at a rate of 10°C/min and by measuring over a temperature range of 40 to 300°C. n is a positive number, and A is a divalent organic group, ΔHm' is a quantity of heat of fusion (J/g) inclusive of heat of crystallization while the temperature is being elevated, ΔHc is a quantity of heat (J/g) generated by the crystallization, and ΔHm is a quantity of heat of fusion (J/g), permitting the components to be volatilized in an amount of not more than 2.0% by weight when the temperature is elevated up to 200°C as measured by the TGA, and having a 5% weight loss temperature (Td5%) of not higher than 230°C, wherein: ΔHm' is measured from the area of the endothermic peak of fusion and ΔHc is measured from the area of the exothermic peak of crystallization, when the DSC is carried out in nitrogen atmosphere, by elevating the temperature at a rate of 10°C/min and by measuring over a temperature range of 0 to 250°C; and the TGA used to measure the amount of components to be volatilized and the weight loss temperature is carried out in nitrogen atmosphere, by elevating the temperature at a rate of 10°C/min and by measuring over a temperature range of 40 to 300°C. ΔHm' is measured from the area of the endothermic peak of fusion and ΔHc is measured from the area of the exothermic peak of crystallization, when the DSC is carried out in nitrogen atmosphere, by elevating the temperature at a rate of 10°C/min and by measuring over a temperature range of 0 to 250°C; and the TGA used to measure the amount of components to be volatilized and the weight loss temperature is carried out in nitrogen atmosphere, by elevating the temperature at a rate of 10°C/min and by measuring over a temperature range of 40 to 300°C.
A method for encoding or decoding a bitstream representing a 3D model, comprising: accessing a plurality of instance information associated with the 3D model, each instance being associated with a corresponding pattern and transformation data; the method being characterized by encoding, or decoding, the plurality of instance information for transmission in a bitstream in one of first and second modes, wherein the bitstream comprises a header buffer, and wherein in the first mode, the transformation information associated with each respective instance is grouped in the bitstream with the respective instance on an instance by instance basis, and in the second mode, the transformation information is grouped in the bitstream on a transformation information type by transformation type basis; wherein the header buffer comprises information indicating whether the instance information is grouped in the first mode or in the second mode; determining whether there is a part of the 3D model not included in any repetitive structure; and in response to determining that there is a part of the 3D model not included in any repetitive structure, encoding, or decoding, the part of the 3D model not included in any repetitive structure in the bitstream, wherein information in the header buffer is used to indicate whether there is a part of the 3D model not included in any repetitive structure. accessing a plurality of instance information associated with the 3D model, each instance being associated with a corresponding pattern and transformation data; the method being characterized by encoding, or decoding, the plurality of instance information for transmission in a bitstream in one of first and second modes, wherein the bitstream comprises a header buffer, and wherein in the first mode, the transformation information associated with each respective instance is grouped in the bitstream with the respective instance on an instance by instance basis, and in the second mode, the transformation information is grouped in the bitstream on a transformation information type by transformation type basis; wherein the header buffer comprises information indicating whether the instance information is grouped in the first mode or in the second mode; determining whether there is a part of the 3D model not included in any repetitive structure; and in response to determining that there is a part of the 3D model not included in any repetitive structure, encoding, or decoding, the part of the 3D model not included in any repetitive structure in the bitstream, wherein information in the header buffer is used to indicate whether there is a part of the 3D model not included in any repetitive structure.
Shaped sheet metal part formed from a flat steel product comprising a steel substrate composed of steel consisting of, as well as iron and unavoidable impurities, in % by weight, C: 0.06-0.5%, Si: 0.05-0.6%, Mn: 0.4-3.0%, Al: 0.06-1.0%, Nb: 0.001-0.2%, Ti: 0.001-0.10%, B: 0.0005-0.01%, P: ≤ 0.03%, S: ≤ 0.02%, N: ≤ 0.02%, Sn: ≤ 0.03%, As: ≤ 0.01%, and optionally one or more of the elements Cr, Cu, Mo, Ni, V, Ca, W in the following contents: Cr: 0.01-1.0%, Cu: 0.01-0.2%, Mo: 0.002-0.3%, Ni: 0.01-0.5%, V: 0.001-0.3%, Ca: 0.0005-0.005%, W: 0.001-1.0%, where the content of unavoidable impurities adds up to a total of not more than 0.2% by weight, where the following conditions are applicable to the Al/Nb ratio of Al content to Nb content: Al/Nb ≤ 20.0 when Mn ≤ 1.6% by weight and Al/Nb ≤ 30.0 when Mn ≥ 1.7% by weight, and an anticorrosion coating, characterized in that the shaped sheet metal part has precipitates in the microstructure in the form of niobium carbonitrides and/or titanium carbonitrides, where more than 80% of all precipitates have a diameter of less than 30 nm, measured as set out in the description. and optionally one or more of the elements Cr, Cu, Mo, Ni, V, Ca, W in the following contents: Cr: 0.01-1.0%, Cu: 0.01-0.2%, Mo: 0.002-0.3%, Ni: 0.01-0.5%, V: 0.001-0.3%, Ca: 0.0005-0.005%, W: 0.001-1.0%, where the content of unavoidable impurities adds up to a total of not more than 0.2% by weight, where the following conditions are applicable to the Al/Nb ratio of Al content to Nb content: Al/Nb ≤ 20.0 when Mn ≤ 1.6% by weight and Al/Nb ≤ 30.0 when Mn ≥ 1.7% by weight, Al/Nb ≤ 20.0 when Mn ≤ 1.6% by weight and Al/Nb ≤ 30.0 when Mn ≥ 1.7% by weight, and an anticorrosion coating, characterized in that the shaped sheet metal part has precipitates in the microstructure in the form of niobium carbonitrides and/or titanium carbonitrides, where more than 80% of all precipitates have a diameter of less than 30 nm, measured as set out in the description.
A process for the preparation of aqueous solutions of methylglycine-N,N-diacetic acid trialkali metal salts by Strecker synthesis, starting from an aqueous solution of α-alanine, by reaction with formaldehyde and hydrocyanic acid to give α-alanine-N,N-diacetonitrile in one reaction unit and saponification thereof with a base to give the aqueous solution of the corresponding methylglycine-N,N-diacetic acid trialkali metal salt, wherein - the α-alanine is partially neutralized and - the addition of the formaldehyde and the hydrocyanic acid for the conversion to the α-alanine-N,N-diacetonitrile is controlled such that the concentration of free hydrocyanic acid in the aqueous reaction mixture at any time is limited such that secondary reactions, in particular to give formaldehyde cyanohydrin, including consecutive reactions of formaldehyde cyanohydrin, and also the polymerization of hydrocyanic acid take place only insofar as the aqueous solution of the methylglycine-N,N-diacetic acid trialkali metal salt has a nitrilotriacetic acid trialkali metal salt content of less than 0.1% by weight at a concentration of 40% by weight of the methylglycine-N,N-diacetic acid trialkali metal salt, based on the total weight of the aqueous methylglycine-N,N-diacetic acid trialkali metal salt solution, such that the concentration of free hydrocyanic acid in the liquid reaction mixture at no time is 10 mol%, based on the amount of hydrocyanic acid metered in, or such that the maximum concentration of free hydrocyanic acid in the liquid reaction mixture does not exceed 20 mol% of free hydrocyanic acid, based on the amount of partially neutralized α-alanine metered in. - the α-alanine is partially neutralized and - the addition of the formaldehyde and the hydrocyanic acid for the conversion to the α-alanine-N,N-diacetonitrile is controlled such that the concentration of free hydrocyanic acid in the aqueous reaction mixture at any time is limited such that secondary reactions, in particular to give formaldehyde cyanohydrin, including consecutive reactions of formaldehyde cyanohydrin, and also the polymerization of hydrocyanic acid take place only insofar as the aqueous solution of the methylglycine-N,N-diacetic acid trialkali metal salt has a nitrilotriacetic acid trialkali metal salt content of less than 0.1% by weight at a concentration of 40% by weight of the methylglycine-N,N-diacetic acid trialkali metal salt, based on the total weight of the aqueous methylglycine-N,N-diacetic acid trialkali metal salt solution, such that the concentration of free hydrocyanic acid in the liquid reaction mixture at no time is 10 mol%, based on the amount of hydrocyanic acid metered in, or such that the maximum concentration of free hydrocyanic acid in the liquid reaction mixture does not exceed 20 mol% of free hydrocyanic acid, based on the amount of partially neutralized α-alanine metered in.
A method for use in a wireless transmit/receive unit, WTRU, for antenna selection, the method comprising: adjusting a candidate set of antenna mappings, to reflect changing channel conditions, wherein the candidate set is a subset of all possible antenna mappings and a collection of antenna mappings available of selection, where an antenna mapping includes a combination of a radio frequency, RF, chain selected from a plurality of RF chains and an antenna element selected from a plurality of antenna elements; selecting a first antenna mapping from the candidate set of antenna mappings; and transmitting data using the first antenna mapping. adjusting a candidate set of antenna mappings, to reflect changing channel conditions, wherein the candidate set is a subset of all possible antenna mappings and a collection of antenna mappings available of selection, where an antenna mapping includes a combination of a radio frequency, RF, chain selected from a plurality of RF chains and an antenna element selected from a plurality of antenna elements; selecting a first antenna mapping from the candidate set of antenna mappings; and transmitting data using the first antenna mapping.