An endoluminal access device (800, 900, 1000) comprising: an outer sheath (812, 912) defining a lumen; a guide assembly including, an inner shaft; and an expandable portion (810, 910) sharing a common longitudinal axis with the inner shaft, the expandable portion (810, 910) configured to be transitioned between a collapsed configuration having a first diameter and an expanded configuration having a second diameter that is greater than the first diameter, the expandable portion (810, 910) including: a first arm defining a first end portion, a second end portion, an intermediate portion, a first lumen, and an aperture positioned at the intermediate portion and in communication with the first lumen, the expandable portion (810, 910) being configured to expand outwardly from a central longitudinal axis when the expandable portion (810, 910) transitions to the expanded configuration and to deflect inwardly toward the central longitudinal axis when the expandable portion (810, 910) is transitioned from the expanded configuration to the collapsed configuration; and an endoluminal tool deliverable from the first lumen of the first arm (830, 930) and outwardly from the aperture of the first arm (830, 930). an outer sheath (812, 912) defining a lumen; a guide assembly including, an inner shaft; and an expandable portion (810, 910) sharing a common longitudinal axis with the inner shaft, the expandable portion (810, 910) configured to be transitioned between a collapsed configuration having a first diameter and an expanded configuration having a second diameter that is greater than the first diameter, the expandable portion (810, 910) including: a first arm defining a first end portion, a second end portion, an intermediate portion, a first lumen, and an aperture positioned at the intermediate portion and in communication with the first lumen, the expandable portion (810, 910) being configured to expand outwardly from a central longitudinal axis when the expandable portion (810, 910) transitions to the expanded configuration and to deflect inwardly toward the central longitudinal axis when the expandable portion (810, 910) is transitioned from the expanded configuration to the collapsed configuration; and an inner shaft; and an expandable portion (810, 910) sharing a common longitudinal axis with the inner shaft, the expandable portion (810, 910) configured to be transitioned between a collapsed configuration having a first diameter and an expanded configuration having a second diameter that is greater than the first diameter, the expandable portion (810, 910) including: a first arm defining a first end portion, a second end portion, an intermediate portion, a first lumen, and an aperture positioned at the intermediate portion and in communication with the first lumen, the expandable portion (810, 910) being configured to expand outwardly from a central longitudinal axis when the expandable portion (810, 910) transitions to the expanded configuration and to deflect inwardly toward the central longitudinal axis when the expandable portion (810, 910) is transitioned from the expanded configuration to the collapsed configuration; and an endoluminal tool deliverable from the first lumen of the first arm (830, 930) and outwardly from the aperture of the first arm (830, 930).