Exposure apparatus for carrying out in vitro experiments with technical replicates of at least one biological test system, to which an exposure medium can be applied by perfusion, forming an exposure atmosphere above the biological test system, comprising • an exposure attachment, which is dimensioned in such a way that this can be mounted on a standard multiwell plate and connected to the latter by means of suitable connecting elements, wherein the exposure attachment has multiple line elements each having at least one feed line and at least one discharge line for an exposure medium, • wherein each line element projects out of the side of the exposure attachment facing the standard multiwell plate and is assigned to a specific well of the standard multiwell plate, forming the exposure atmosphere within the specific well, • wherein the wells are receptacles which are already integrated in the standard multiwell plate or those which are accommodated, as separate culture vessels, so-called inserts, in existing integrated wells or in appropriately arranged recesses in the standard multiwell plate, • wherein the exposure attachment has an attachment holding frame that can be placed on the standard multiwell plate and connected to the latter by means of the connecting elements, and also an attachment head that is movably arranged on the attachment holding frame and connected to the latter, • wherein, following the placement of the exposure attachment on the standard multiwell plate, the line element respectively assigned to a specific well can be moved into the specific well by moving the attachment head interacting with the line elements in the direction of the attachment holding frame and standard multiwell plate, and can be inserted in such a way that a sealing means provided on the outside of the line element and running around the latter seals the line element tightly against the inner wall of the well to form an exposure atmosphere that is sealed off during the in vitro experiment within each specific well, • wherein exposure medium can be supplied and discharged only via the respectively associated line element, wherein, for or during the performance of the experiment, the attachment head can be locked to the attachment holding frame by means of locking and unlocking elements preferably arranged on the attachment head in such a way that the line elements are fixed, wherein the locking elements hold the attachment head and the attachment holding frame together, preferably under tension, and wherein, following the performance of the experiment, the attachment head can be unlocked from the attachment holding frame by means of the locking and unlocking elements, in such a way that the line elements together with the circumferential sealing means can be detached from the wells with a movement of the attachment head in the opposite direction to the previous. • an exposure attachment, which is dimensioned in such a way that this can be mounted on a standard multiwell plate and connected to the latter by means of suitable connecting elements, wherein the exposure attachment has multiple line elements each having at least one feed line and at least one discharge line for an exposure medium, • wherein each line element projects out of the side of the exposure attachment facing the standard multiwell plate and is assigned to a specific well of the standard multiwell plate, forming the exposure atmosphere within the specific well, • wherein the wells are receptacles which are already integrated in the standard multiwell plate or those which are accommodated, as separate culture vessels, so-called inserts, in existing integrated wells or in appropriately arranged recesses in the standard multiwell plate, • wherein the exposure attachment has an attachment holding frame that can be placed on the standard multiwell plate and connected to the latter by means of the connecting elements, and also an attachment head that is movably arranged on the attachment holding frame and connected to the latter, • wherein, following the placement of the exposure attachment on the standard multiwell plate, the line element respectively assigned to a specific well can be moved into the specific well by moving the attachment head interacting with the line elements in the direction of the attachment holding frame and standard multiwell plate, and can be inserted in such a way that a sealing means provided on the outside of the line element and running around the latter seals the line element tightly against the inner wall of the well to form an exposure atmosphere that is sealed off during the in vitro experiment within each specific well, • wherein exposure medium can be supplied and discharged only via the respectively associated line element, wherein, for or during the performance of the experiment, the attachment head can be locked to the attachment holding frame by means of locking and unlocking elements preferably arranged on the attachment head in such a way that the line elements are fixed, wherein the locking elements hold the attachment head and the attachment holding frame together, preferably under tension, and wherein, following the performance of the experiment, the attachment head can be unlocked from the attachment holding frame by means of the locking and unlocking elements, in such a way that the line elements together with the circumferential sealing means can be detached from the wells with a movement of the attachment head in the opposite direction to the previous.