mhurhangee/ep-ind-claims huggingface dataset:
An implantable medical device for controlled drug delivery device comprising: a first drug portion that comprises a first drug housing loaded with a first drug formulation comprising a first drug in a solid or semi-solid form, wherein the first drug housing comprises a first wall that is permeable to water but is substantially impermeable to the first drug and has at least one passageway through the first wall, the first drug portion releasing the first drug in vivo according to a first release profile; and a second drug portion that comprises a second drug housing loaded with a second drug formulation comprising a second drug in a solid or semi-solid form, wherein the second drug housing comprises a second wall that is permeable to water and to the second drug, the second drug portion releasing the second drug in vivo according to a second release profile, the second release profile differing from the first release profile; and a retention portion operably associated with both the first and second drug portions (1202, 1204), wherein the first and second drug housings are partitioned regions of a single tubular body, the first and second walls comprising a polymer selected from silicone and medical grades of poly(vinyl chloride), polyolefins, and polyether urethanes, wherein the first drug has a charge and/or molecular size which renders the first wall impermeable to the first drug, and wherein the second drug has a charge and/or molecular size which renders the second wall permeable to the second drug. a first drug portion that comprises a first drug housing loaded with a first drug formulation comprising a first drug in a solid or semi-solid form, wherein the first drug housing comprises a first wall that is permeable to water but is substantially impermeable to the first drug and has at least one passageway through the first wall, the first drug portion releasing the first drug in vivo according to a first release profile; and a second drug portion that comprises a second drug housing loaded with a second drug formulation comprising a second drug in a solid or semi-solid form, wherein the second drug housing comprises a second wall that is permeable to water and to the second drug, the second drug portion releasing the second drug in vivo according to a second release profile, the second release profile differing from the first release profile; and a retention portion operably associated with both the first and second drug portions (1202, 1204), wherein the first and second drug housings are partitioned regions of a single tubular body, the first and second walls comprising a polymer selected from silicone and medical grades of poly(vinyl chloride), polyolefins, and polyether urethanes, wherein the first drug has a charge and/or molecular size which renders the first wall impermeable to the first drug, and wherein the second drug has a charge and/or molecular size which renders the second wall permeable to the second drug.
A method for a receiving wireless device (202r, 1300) for communicating in a wireless network, the method comprising: receiving an initial portion of a data packet (505, 605, 705, 800) from a transmitting wireless device (202t, 1200); determining that the receiving wireless device (202r, 1300) is the intended receiver of the data packet (505, 605, 705, 800); and transmitting a reservation signal (515, 615, 715) on a dedicated channel (530, 630, 730) not used for data communication based on determining the receiving wireless device (202r, 1300) is the intended receiver, the reservation signal (515, 615, 715) being configured to reserve one or more communication channels (520, 620, 720) for the receiving wireless device (202r, 1300) to receive the data packet (505, 605, 705, 800) from the transmitting wireless device (202t, 1200), wherein the reservation signal (515, 615, 715) is transmitted as long as the wireless device (202r, 1300) intends to reserve the one or more communication channels (520, 620, 720), and wherein the dedicated channel (530, 630, 730) is different than the one or more communication channels (520, 620, 720) but is associated with the one or more communication channels (520, 620,720). receiving an initial portion of a data packet (505, 605, 705, 800) from a transmitting wireless device (202t, 1200); determining that the receiving wireless device (202r, 1300) is the intended receiver of the data packet (505, 605, 705, 800); and transmitting a reservation signal (515, 615, 715) on a dedicated channel (530, 630, 730) not used for data communication based on determining the receiving wireless device (202r, 1300) is the intended receiver, the reservation signal (515, 615, 715) being configured to reserve one or more communication channels (520, 620, 720) for the receiving wireless device (202r, 1300) to receive the data packet (505, 605, 705, 800) from the transmitting wireless device (202t, 1200), wherein the reservation signal (515, 615, 715) is transmitted as long as the wireless device (202r, 1300) intends to reserve the one or more communication channels (520, 620, 720), and wherein the dedicated channel (530, 630, 730) is different than the one or more communication channels (520, 620, 720) but is associated with the one or more communication channels (520, 620,720).
A skin perfusion pressure determination device comprising: a sensor module having a first sensor for sensing a first parameter associated with a pressure exerted on a target area by the sensor module and a second sensor for sensing a second parameter associated with an amount of blood perfusion at the target area, wherein the first sensor and the second sensor are arranged such that, when the sensor module is pressed against the target area the first sensor produces an output corresponding to the sensed first parameter and the second sensor produces an output corresponding to the sensed second parameter, and further comprising a processor for processing an output of the first sensor and an output of the second sensor, wherein the processor is configured to determine that the output of the second sensor satisfies a predetermined condition associated with a predetermined amount of blood perfusion at the target area and wherein the predetermined condition is a condition which corresponds to an amount of blood perfusion at the target area which exceeds a predetermined threshold, characterized in that the first sensor comprises a force sensor arranged such that when the sensor module is pressed against the target area, the second sensor is disposed between the target area and the force sensor to determine the force exerted by the sensor module on the target area a sensor module having a first sensor for sensing a first parameter associated with a pressure exerted on a target area by the sensor module and a second sensor for sensing a second parameter associated with an amount of blood perfusion at the target area, wherein the first sensor and the second sensor are arranged such that, when the sensor module is pressed against the target area the first sensor produces an output corresponding to the sensed first parameter and the second sensor produces an output corresponding to the sensed second parameter, and further comprising a processor for processing an output of the first sensor and an output of the second sensor, wherein the processor is configured to determine that the output of the second sensor satisfies a predetermined condition associated with a predetermined amount of blood perfusion at the target area and wherein the predetermined condition is a condition which corresponds to an amount of blood perfusion at the target area which exceeds a predetermined threshold, characterized in that the first sensor comprises a force sensor arranged such that when the sensor module is pressed against the target area, the second sensor is disposed between the target area and the force sensor to determine the force exerted by the sensor module on the target area
(Currently Amended) A burner, the burner comprising: a mixing and dispensing unit configured to mix a fuel gas and air, which are to be supplied, and dispense the mixture; a combustion catalyst unit configured to generate heat by a catalytic combustion reaction with the fuel gas supplied from the mixing and dispensing unit; and a premixing chamber configured to pre-mix the fuel gas introduced into the combustion catalyst unit while connecting the mixing and dispensing unit to the combustion catalyst unit, wherein the combustion catalyst unit comprises: a housing having a chamber therein and openings at front and rear sides thereof; perforated plates installed on front and rear surfaces of the housing and allowing the fuel gas to pass from the rear side to the front side of the housing; a pellet-type high-temperature combustion catalyst with which an inside of the chamber of the housing is filled; and a heat source means configured to generate a heat source for catalytic combustion of the combustion catalyst, characterised in that the pellet-type high-temperature combustion catalyst is prepared by preparing a metal precursor solution including a transition metal nitrate, an alkaline earth metal nitrate, and aluminum nitrate; preparing a precipitation solution; preparing a mixed solution by mixing the metal precursor solution and the precipitation solution; raising a temperature of the mixed solution to 90 °C to 100 °C and holding the mixed solution at 90 °C to 100 °C for 10 hours to 48 hours to cause a precipitation reaction; filtering a precipitate slurry formed by the precipitation reaction to be separated from the mixed solution; washing the precipitate slurry with water (S 160); drying the washed precipitate slurry to remove moisture therefrom; and performing calcination at 1,000 °C to 1,500 °C to remove moisture remaining in the dried precipitate slurry.
A combing machine having a nipper unit that can be pivoted back and forth and that has a lower nipper plate and an upper, movably mounted nipper plate, and further having a top comb and a combing cylinder rotatably mounted within a housing below the nipper unit, wherein the housing is connected to a low-pressure source and has at least one opening which is connected to the space between the nipper unit and a first subsequent first roller pair, downstream of which a second roller pair is arranged, and a rotatable cleaning element is attached above the upper pressure rollers (24b, 25b) and the first and second roller pairs (24, 25), characterized in that in the region between the nipper unit and the cleaning element, a shielding element is attached that extends over the length of the cleaning element, wherein the lower longitudinal edge of the upwardly extending shielding element is arranged at a distance (a) between 0.1 mm and 7 mm from the circumferential surface of the pressure roller of the first roller pair.
A method for chemically modifying particles of a bicarbonate salt in a co-rotating twin-screw extruder, the method comprising: feeding the particles into an intake zone of the extruder; processing the fed particles in a heat-treatment zone of the extruder at a temperature in the range of 200 0 C to 350 0 C for a residence time in the range 3 to 20 seconds to convert 3% to 40% w/w of the bicarbonate salt present in the fed particles into a carbonate salt, thereby chemically modifying the particles; and collecting the chemically modified particles from the extruder. feeding the particles into an intake zone of the extruder; processing the fed particles in a heat-treatment zone of the extruder at a temperature in the range of 200 0 C to 350 0 C for a residence time in the range 3 to 20 seconds to convert 3% to 40% w/w of the bicarbonate salt present in the fed particles into a carbonate salt, thereby chemically modifying the particles; and collecting the chemically modified particles from the extruder.
A liquid desiccant system for controlling a temperature inside an enclosure, the system comprising: a liquid desiccant evaporative cooler, LDEC, system configured to cool down an incoming air stream entering the enclosure; a liquid desiccant humidity recovery, LDHR, system configured to remove humidity from a humid air stream that exists in the enclosure; and a storage system fluidly connected to the LDHR system, characterized in that the LDEC system is configured to use a first liquid desiccant to cool down the incoming air stream, the LDHR system is configured to use a second liquid desiccant to remove humidity from the humid air stream, the storage system is fluidly connected to the LDEC system and is configured to separately store the first liquid desiccant and the second liquid desiccant, and the humid air stream includes water vapors from the first liquid desiccant and from inside the enclosure. a liquid desiccant evaporative cooler, LDEC, system configured to cool down an incoming air stream entering the enclosure; a liquid desiccant humidity recovery, LDHR, system configured to remove humidity from a humid air stream that exists in the enclosure; and a storage system fluidly connected to the LDHR system, characterized in that the LDEC system is configured to use a first liquid desiccant to cool down the incoming air stream, the LDHR system is configured to use a second liquid desiccant to remove humidity from the humid air stream, the storage system is fluidly connected to the LDEC system and is configured to separately store the first liquid desiccant and the second liquid desiccant, and the humid air stream includes water vapors from the first liquid desiccant and from inside the enclosure.
A controller of an internal combustion engine with a supercharger, which includes, for each of cylinders, fuel supply means for supplying a fuel in the cylinder and an ignition plug, characterized by including: ignition timing setting means for setting a basic ignition timing for generating a spark by the ignition plug depending on an operation state of the internal combustion engine; abnormal combustion generation cylinder detection means for detecting, for each cycle; an abnormal combustion generation cylinder in which an abnormal combustion is generated in a supercharged region; fuel cut execution means for executing a fuel cut to stop a fuel supply by the fuel supply means for the abnormal combustion generation cylinder; and ignition control means during fuel cut execution for changing an ignition timing such that a crank angle width between a compression top dead center and the basic ignition timing is expanded for several cycles after start of the fuel cut, and, further after elapse of the several cycles, executing an ignition cut that prohibits a spark from being generated by the ignition plug, for the abnormal combustion generation cylinder. ignition timing setting means for setting a basic ignition timing for generating a spark by the ignition plug depending on an operation state of the internal combustion engine; abnormal combustion generation cylinder detection means for detecting, for each cycle; an abnormal combustion generation cylinder in which an abnormal combustion is generated in a supercharged region; fuel cut execution means for executing a fuel cut to stop a fuel supply by the fuel supply means for the abnormal combustion generation cylinder; and ignition control means during fuel cut execution for changing an ignition timing such that a crank angle width between a compression top dead center and the basic ignition timing is expanded for several cycles after start of the fuel cut, and, further after elapse of the several cycles, executing an ignition cut that prohibits a spark from being generated by the ignition plug, for the abnormal combustion generation cylinder.
A method of managing multimedia communication recordings in a mobile electronic device, comprising: recording a multimedia communication comprising one of a voice call and a video conference, and storing the recording in a memory of the mobile electronic device; detecting (515: Yes) at least one event indicating that the communication has been placed on hold; detecting (525: Yes) at least one further event indicating that the communication has resumed; wherein detecting (515: Yes) at least one event and detecting (525: Yes) at least one further event is performed during the multimedia communication, while recording and storing the multimedia communication; responsive to detecting (525: Yes) the at least one further event, inserting a bookmark in the recording at a position corresponding to the occurrence of the at least one event, wherein the information contained in the bookmark comprises an indicator of the time at which the at least one event was detected, an identifier indicating the type of the at least one event, and an indicator of the time at which the at least one further event was detected; and responsive to termination of the call, generating an audible tag based on the information contained in the bookmark, and inserting the audible tag in the recording at the position of the bookmark, the audible tag generated from pre-recorded audio files and including at least one audible descriptor for the at least one event. recording a multimedia communication comprising one of a voice call and a video conference, and storing the recording in a memory of the mobile electronic device; detecting (515: Yes) at least one event indicating that the communication has been placed on hold; detecting (525: Yes) at least one further event indicating that the communication has resumed; wherein detecting (515: Yes) at least one event and detecting (525: Yes) at least one further event is performed during the multimedia communication, while recording and storing the multimedia communication; responsive to detecting (525: Yes) the at least one further event, inserting a bookmark in the recording at a position corresponding to the occurrence of the at least one event, wherein the information contained in the bookmark comprises an indicator of the time at which the at least one event was detected, an identifier indicating the type of the at least one event, and an indicator of the time at which the at least one further event was detected; and responsive to termination of the call, generating an audible tag based on the information contained in the bookmark, and inserting the audible tag in the recording at the position of the bookmark, the audible tag generated from pre-recorded audio files and including at least one audible descriptor for the at least one event.
Tolerance compensation arrangement for fastening a first component to a second component with an automatic compensation of tolerances in the spacing between the first component and the second component, comprising the following features: a. a base element with a first inner thread as well as a fastening structure at an outside for fastening the base element in an opening of the first component, b. an adjusting unit with a first outer thread, with the first outer thread together with the first inner thread of the base element forming a first thread pairing of a first thread direction and the adjusting unit comprising a fastening sleeve with a second inner thread adjacent to a first axial end, and c. a dragging unit being arranged at least partly in the adjusting unit adjacent to a second axial end, characterized in that d. a fastening screw can be screwed into the second inner thread of the fastening sleeve first by rotating in the second thread direction via a second thread pairing of a second thread direction contrary to the first thread direction, and can subsequently be connected with the dragging unit by means of a releaseable dragging connection, so that when rotating the fastening screw, the adjusting unit can be co-rotated and is movable in abutment with the second component and after that, a radial press fit between adjusting unit and base element can be established. a. a base element with a first inner thread as well as a fastening structure at an outside for fastening the base element in an opening of the first component, b. an adjusting unit with a first outer thread, with the first outer thread together with the first inner thread of the base element forming a first thread pairing of a first thread direction and the adjusting unit comprising a fastening sleeve with a second inner thread adjacent to a first axial end, and c. a dragging unit being arranged at least partly in the adjusting unit adjacent to a second axial end, characterized in that d. a fastening screw can be screwed into the second inner thread of the fastening sleeve first by rotating in the second thread direction via a second thread pairing of a second thread direction contrary to the first thread direction, and can subsequently be connected with the dragging unit by means of a releaseable dragging connection, so that when rotating the fastening screw, the adjusting unit can be co-rotated and is movable in abutment with the second component and after that, a radial press fit between adjusting unit and base element can be established.
An isolated chimeric or humanized antibody which specifically binds to glycosylated PD-L1, wherein the antibody comprises a V H domain comprising a CDR H1 with an amino acid sequence of SEQ ID NO: 4, a CDR H2 with an amino acid sequence of SEQ ID NO: 6, and a CDR H3 with an amino acid sequence of SEQ ID NO: 8 or a V H domain comprising a CDR H1 with an amino acid sequence of SEQ ID NO: 5, a CDR H2 with an amino acid sequence of SEQ ID NO: 7, and a CDR H3 with an amino acid sequence of SEQ ID NO: 9 and a V L domain comprising a CDR L1 with an amino acid sequence of SEQ ID NO: 12, a CDR L2 with an amino acid sequence of SEQ ID NO: 14, and a CDR L3 with an amino acid sequence of SEQ ID NO: 16 or wherein the antibody comprises a V H domain comprising a CDR H1 with an amino acid sequence of SEQ ID NO: 20, a CDR H2 with an amino acid sequence of SEQ ID NO: 22, and a CDR H3 with an amino acid sequence of SEQ ID NO: 24, or a V H comprising a CDR H1 with an amino acid sequence of SEQ ID NO: 21 a CDR H2 with an amino acid sequence of SEQ ID NO: 23, and a CDR H3 with an amino acid sequence of SEQ ID NO: 25 and a V L domain comprising a CDR L1 with an amino acid sequence of SEQ ID NO: 28, a CDR L2 with an amino acid sequence of SEQ ID NO: 30, and a CDR L3 with an amino acid sequence of SEQ ID NO: 32.