mhurhangee/ep-ind-claims huggingface dataset:
A variant polypeptide having geranylgeranyl pyrophosphate synthase activity, which variant polypeptide comprises an amino acid sequence which, when aligned with a geranylgeranyl pyrophosphate synthase comprising the sequence set out in SEQ ID NO: 1, comprises at least one substitution of an amino acid residue corresponding to any of amino acids at positions 92, 100 or 235, said positions being defined with reference to SEQ ID NO: 1, wherein said variant polypeptide has one or more modified properties as compared with a reference polypeptide having geranylgeranyl pyrophosphate synthase activity and wherein said variant polypeptide has at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 97%, at least 98% or at least 99% sequence identity with SEQ ID NO: 1 or SEQ ID NO: 17.
A closed-loop system, comprising: (a) a first device configured to detect a physiological signal; (b) an interrogator comprising one or more ultrasonic transducers configured to receive an ultrasonic backscatter encoding the physiological signal and emit ultrasonic waves encoding a trigger signal; and (c) a second device configured to emit an electrical pulse in response to the trigger signal, wherein the second device is implantable, comprising: an ultrasonic transducer configured to receive ultrasonic waves that power the second device and encode the trigger signal; a first electrode and a second electrode configured to be in electrical communication with a tissue and emit an electrical pulse to the tissue in response to the trigger signal; and an integrated circuit comprising an energy storage circuit. (a) a first device configured to detect a physiological signal; (b) an interrogator comprising one or more ultrasonic transducers configured to receive an ultrasonic backscatter encoding the physiological signal and emit ultrasonic waves encoding a trigger signal; and (c) a second device configured to emit an electrical pulse in response to the trigger signal, wherein the second device is implantable, comprising: an ultrasonic transducer configured to receive ultrasonic waves that power the second device and encode the trigger signal; a first electrode and a second electrode configured to be in electrical communication with a tissue and emit an electrical pulse to the tissue in response to the trigger signal; and an integrated circuit comprising an energy storage circuit. an ultrasonic transducer configured to receive ultrasonic waves that power the second device and encode the trigger signal; a first electrode and a second electrode configured to be in electrical communication with a tissue and emit an electrical pulse to the tissue in response to the trigger signal; and an integrated circuit comprising an energy storage circuit.
A sensor element, comprising: an element body; paired lead wires drawn out from the element body; and stranded wires that are each obtained by twisting a plurality of core wires and are joined to the respective paired lead wires in a joining structure by welding, wherein each of the core wires includes a wire body and a plating layer covering the wire body, the wire body being made of copper and the plating layer being made of tin; the joining structure includes a main joining region provided in a predetermined region in an axis direction, a first sub-joining region adjacent to the main joining region and a second sub-joining region adjacent to the main joining region, the first sub-joining region and the second sub-joining region being provided on both sides of the main joining region in the axis direction; the concentration of tin in the main joining region is higher than the concentration of tin in each of the first sub-joining region and the second sub-joining region; and the joining strength of each of the lead wires and the corresponding stranded wire is higher in the main joining region than in each of the first sub-joining region and the second sub-joining region. an element body; paired lead wires drawn out from the element body; and stranded wires that are each obtained by twisting a plurality of core wires and are joined to the respective paired lead wires in a joining structure by welding, wherein each of the core wires includes a wire body and a plating layer covering the wire body, the wire body being made of copper and the plating layer being made of tin; the joining structure includes a main joining region provided in a predetermined region in an axis direction, a first sub-joining region adjacent to the main joining region and a second sub-joining region adjacent to the main joining region, the first sub-joining region and the second sub-joining region being provided on both sides of the main joining region in the axis direction; the concentration of tin in the main joining region is higher than the concentration of tin in each of the first sub-joining region and the second sub-joining region; and the joining strength of each of the lead wires and the corresponding stranded wire is higher in the main joining region than in each of the first sub-joining region and the second sub-joining region.
A therapeutic agent comprising an interleukin 6 (IL-6) inhibitor as an active ingredient for use in the treatment of mental illness of a patient having attenuation of a prepulse inhibitory effect, wherein the IL-6 inhibitor is an anti-IL-6 receptor antibody or an anti-IL-6 antibody which suppresses the attenuation of a prepulse inhibitory effect and wherein the mental illness is schizophrenia, Tourette syndrome, and/or obsessive compulsive neurosis.
A support for the neck and head of a human being, comprising a right and a left elongated support member (101,102; 201,202; 302;303; 401,402; 400A,401A; 500,502; 504,506; 906,908) adapted to extend in the human being's cranial-caudal direction, and a collapsible intermediate section (100,106; 200; 300,305; 400; 510,512; 910) interconnecting the right and left elongated support members, wherein each of the elongated support members and the collapsible intermediate section are sufficiently bendable to conform to the natural contour of the left and right neck and head portions of the human being, characterised in that - the support is dimensioned to extend only behind the human being's ears, with no portion of the support supporting or touching the human being's cheeks or jaws during use; - the elongated support members have a diameter of at most 5 cm; - the elongated support members are essentially incompressible under the weight of the individual's head, the elongated support members being adapted to support a right and a left portion of the back head and neck, whereby at transitions between the collapsible intermediate section and the elongated support members, the elongated support members define left and right edges for engaging the human being's neck and mastoid bones behind the human being's ears to provide a support for the human being's head when the support is under pressure from the human being's head and neck. - the support is dimensioned to extend only behind the human being's ears, with no portion of the support supporting or touching the human being's cheeks or jaws during use; - the elongated support members have a diameter of at most 5 cm; - the elongated support members are essentially incompressible under the weight of the individual's head, the elongated support members being adapted to support a right and a left portion of the back head and neck, whereby at transitions between the collapsible intermediate section and the elongated support members, the elongated support members define left and right edges for engaging the human being's neck and mastoid bones behind the human being's ears to provide a support for the human being's head when the support is under pressure from the human being's head and neck.
A flexible electro-active lens lens characterised by: a flexible housing having a fixed refractive index; an electro-active element embedded in the flexible housing and having an alterable refractive index that provides an optical power adapted for changing within an optical power range of from a minimum optical power to a maximum optical power; a power source, in electrical communication with the electro-active element, to power the electro-active element; and a memory metal material configured to inductively charge the power source using electrical power and/or to receive control signals transmitted wirelessly from a device external to the flexible electro-active lens. a flexible housing having a fixed refractive index; an electro-active element embedded in the flexible housing and having an alterable refractive index that provides an optical power adapted for changing within an optical power range of from a minimum optical power to a maximum optical power; a power source, in electrical communication with the electro-active element, to power the electro-active element; and a memory metal material configured to inductively charge the power source using electrical power and/or to receive control signals transmitted wirelessly from a device external to the flexible electro-active lens.
A vascular repair device, comprising: a tubular graft body having an upstream end, a downstream end, and an interior surface; and a clasping stent at the upstream end of the graft body that is partially attached to said interior surface of said graft body, said graft body entirely covering said clasping stent, said clasping stent having a circumference defining upstream apices, downstream apices, and struts connecting respective adjacent ones of said upstream and downstream apices, each of said struts having an upstream portion and a downstream portion, said upstream portion of at least some of said struts being unattached from said interior surface of said graft body, and some of said upstream apices adjacent said unattached struts being unattached from said interior surface of said graft body; and a crown stent between the clasping stent and the upstream end of said graft body and fixed to said graft body adjacent to said clasping stent, the crown stent including upstream and downstream apices and struts connecting said upstream and said downstream apices, wherein said upstream apices of said clasping stent are nested between downstream apices of said crown stent. a tubular graft body having an upstream end, a downstream end, and an interior surface; and a clasping stent at the upstream end of the graft body that is partially attached to said interior surface of said graft body, said graft body entirely covering said clasping stent, said clasping stent having a circumference defining upstream apices, downstream apices, and struts connecting respective adjacent ones of said upstream and downstream apices, each of said struts having an upstream portion and a downstream portion, said upstream portion of at least some of said struts being unattached from said interior surface of said graft body, and some of said upstream apices adjacent said unattached struts being unattached from said interior surface of said graft body; and a crown stent between the clasping stent and the upstream end of said graft body and fixed to said graft body adjacent to said clasping stent, the crown stent including upstream and downstream apices and struts connecting said upstream and said downstream apices, wherein said upstream apices of said clasping stent are nested between downstream apices of said crown stent.
A system, comprising: a) a display having a first pixel array and a gap in the first pixel array in which at least some pixels of the first pixel array are missing; b) a camera positioned below the first pixel array; c) a second pixel array (220, 320, 420) positioned below the first pixel array; and d) an optical element (208, 304, 502), positioned below the gap, and configured to reflect light emitted from the second pixel array into the gap, and further configured to reflect light entering the gap to the camera; wherein the system is operable in a first operation mode in which the camera is operative to capture images by capturing said reflected light entering the gap and the second pixel array is not operative to display information, and in a second operation mode in which the camera is not operative to capture images and the second pixel array is operative to display second array pixel information in the gap in the first pixel array, and wherein the camera and second pixel array are located on opposite sides of the optical element. a) a display having a first pixel array and a gap in the first pixel array in which at least some pixels of the first pixel array are missing; b) a camera positioned below the first pixel array; c) a second pixel array (220, 320, 420) positioned below the first pixel array; and d) an optical element (208, 304, 502), positioned below the gap, and configured to reflect light emitted from the second pixel array into the gap, and further configured to reflect light entering the gap to the camera; wherein the system is operable in a first operation mode in which the camera is operative to capture images by capturing said reflected light entering the gap and the second pixel array is not operative to display information, and in a second operation mode in which the camera is not operative to capture images and the second pixel array is operative to display second array pixel information in the gap in the first pixel array, and wherein the camera and second pixel array are located on opposite sides of the optical element. wherein the system is operable in a first operation mode in which the camera is operative to capture images by capturing said reflected light entering the gap and the second pixel array is not operative to display information, and in a second operation mode in which the camera is not operative to capture images and the second pixel array is operative to display second array pixel information in the gap in the first pixel array, and wherein the camera and second pixel array are located on opposite sides of the optical element.
A computer system comprising: a virtual server configured to provide a plurality of virtual computing sessions; a client device configured to access one of the virtual computing sessions via a communications network, and comprising a wireless transceiver connected to a cellular network; and a server configured to establish a backup communications channel via the cellular network based on said client device losing connectivity to the communications network, with the backup communications channel for said server to restore connectivity for said client device to access one of the virtual computing sessions via the communications network. a virtual server configured to provide a plurality of virtual computing sessions; a client device configured to access one of the virtual computing sessions via a communications network, and comprising a wireless transceiver connected to a cellular network; and a server configured to establish a backup communications channel via the cellular network based on said client device losing connectivity to the communications network, with the backup communications channel for said server to restore connectivity for said client device to access one of the virtual computing sessions via the communications network.
An attachment removing device for a diamond tool for removing an attachment attached to the diamond tool, comprising: a cylindrical member; a plurality of bristles each having one end connected to the cylindrical member; a pair of disk members each connected to both ends of the cylindrical member; and a jig portion including leg members rotatably connected to both ends of the cylindrical member by a shaft and a body from which the leg members are extended, wherein rotation around the shaft is configured to be subjected to predetermined resistance, and the pair of disk members are disposed with the bristles interposed between the disk members to prevent the bristles from being spread to both sides. a cylindrical member; a plurality of bristles each having one end connected to the cylindrical member; a pair of disk members each connected to both ends of the cylindrical member; and a jig portion including leg members rotatably connected to both ends of the cylindrical member by a shaft and a body from which the leg members are extended, wherein rotation around the shaft is configured to be subjected to predetermined resistance, and the pair of disk members are disposed with the bristles interposed between the disk members to prevent the bristles from being spread to both sides.
Waste collection container comprising a waste storage tank having at least one outer side wall, the container also comprising a lining (42; 60) fitted in the tank so as to follow the one or more outer side walls, and spacing means (46; 66) to keep a predetermined distance between the one or more side walls and the lining, the lining comprising a body substantially following the side wall and a plurality of ribs substantially perpendicular to the body of the lining, characterised in that the body of the lining and the ribs are made using the same piece of fabric, the ribs being formed by pleats created in the piece of fabric.
A cylinder liner for a longitudinally scavenged two-stroke large diesel engine with a gas inlet nozzle by means of which a combustion gas provided as fuel can be supplied to a combustion chamber, characterized in that the gas inlet nozzle is an integral part of the cylinder liner and is designed as a bore in the cylinder liner, wherein a nozzle axis of the gas inlet nozzle is arranged at a predeterminable angle (β) with respect to a radial direction of the cylinder liner in such a way that the combustion gas can be injected into the combustion chamber at an angle other than zero with respect to the radial direction.
A method for preparing a bimetallic mercaptan conversion catalyst for sweetening liquefied petroleum gas at a low temperature, comprising the following steps: mixing 60-80 parts by mass of aluminum hydroxide xerogel and 20-40 parts by mass of silica xerogel uniformly, adding a pore-forming agent and an aqueous nitric acid solution thereto, followed by mixing and kneading, and then extruding the resultant to produce a formed article; air-drying the formed article by placing it at room temperature for 8-15 hours, drying it at 90-120°C for 3-5 hours, then calcinating it for 3-8 hours by elevating the temperature to 450-620°C at a heating rate of 2-4°C/min, and subsequently crushing and screening the resultant to produce short-rod-like particles having a size of 4-6 mm, thereby producing an Al 2 O 3 -SiO 2 composite oxide carrier; and loading bimetallic active components, vanadium and nickel, separately onto the Al 2 O 3 -SiO 2 composite oxide carrier by using an incipient wet impregnation method, and then drying and calcinating it to obtain the bimetallic mercaptan conversion catalyst for sweetening LPG at a low temperature, wherein the low temperature sweetening treatment of LPG is carried out at a reaction temperature of 55-150°C. mixing 60-80 parts by mass of aluminum hydroxide xerogel and 20-40 parts by mass of silica xerogel uniformly, adding a pore-forming agent and an aqueous nitric acid solution thereto, followed by mixing and kneading, and then extruding the resultant to produce a formed article; air-drying the formed article by placing it at room temperature for 8-15 hours, drying it at 90-120°C for 3-5 hours, then calcinating it for 3-8 hours by elevating the temperature to 450-620°C at a heating rate of 2-4°C/min, and subsequently crushing and screening the resultant to produce short-rod-like particles having a size of 4-6 mm, thereby producing an Al 2 O 3 -SiO 2 composite oxide carrier; and loading bimetallic active components, vanadium and nickel, separately onto the Al 2 O 3 -SiO 2 composite oxide carrier by using an incipient wet impregnation method, and then drying and calcinating it to obtain the bimetallic mercaptan conversion catalyst for sweetening LPG at a low temperature, wherein the low temperature sweetening treatment of LPG is carried out at a reaction temperature of 55-150°C.
An imaging system for imaging assisted interventional procedure, comprising: - a data receiver configured to receive a stream of images; - a contrast agent detector and an image extractor configured to identify images that have been contrast enhanced through a puff of contrast agent and to extract the identified images from the stream of images; and - a display generator configured to generate a display including live images from the stream of images and a playback loop of the extracted images. - a data receiver configured to receive a stream of images; - a contrast agent detector and an image extractor configured to identify images that have been contrast enhanced through a puff of contrast agent and to extract the identified images from the stream of images; and - a display generator configured to generate a display including live images from the stream of images and a playback loop of the extracted images.
Lamp for illuminating building areas, comprising a circuit board, on which multiple LEDs (12a, 12b, 12c) are arranged, a secondary optics, which bundles the light emitted by the LEDs, and a tertiary optics, wherein the tertiary optics is formed by a planar, translucent element, which has light-directing microstructures, which are formed by facets (19, 19a, 19b, 19c, 19d), the light-directing boundary surfaces of which are formed by curved surfaces or planar surfaces, wherein the facets extend along a structured matrix, wherein the secondary optics is formed by one or more lens bodies, and wherein the secondary optics is arranged between the circuit board and the tertiary optics.
A multidimensional liquid chromatography system, comprising: a switching valve operable in at least two valve states; a detector in communication with the switching valve through a first fluidic path defined by tubing; a routing valve in communication with the switching valve through a second fluidic path defined by tubing; and a first fluidic loop valve in communication with the routing valve through a third fluidic path defined by tubing, wherein the volume of the first fluidic path is equal to the sum of the volume of the second fluidic path and the volume of the third fluidic path. a switching valve operable in at least two valve states; a detector in communication with the switching valve through a first fluidic path defined by tubing; a routing valve in communication with the switching valve through a second fluidic path defined by tubing; and a first fluidic loop valve in communication with the routing valve through a third fluidic path defined by tubing, wherein the volume of the first fluidic path is equal to the sum of the volume of the second fluidic path and the volume of the third fluidic path.
A dust collector comprising: a housing; a telescoping suction pipe coupled to the housing; an electric motor positioned in the housing; a suction fan driven by the electric motor and operable to generate a vacuum in the suction pipe; a dust container coupled to the housing and positioned upstream of the suction fan; and a filter supported by at least one of the housing and the dust container, characterised in that the dust collector further includes a detector coupled to the housing and biased toward a first position in which a portion of the detector protrudes from the housing to prevent the dust container from being coupled to the housing in absence of the filter, the protruding portion of the detector being retractable into the housing in response to the detector being moved to a second position by the filter when the filter is present, thereby permitting the dust container to be coupled to the housing, and wherein the filter is removable from the one of the housing and the dust container for at least one of servicing and replacement. a housing; a telescoping suction pipe coupled to the housing; an electric motor positioned in the housing; a suction fan driven by the electric motor and operable to generate a vacuum in the suction pipe; a dust container coupled to the housing and positioned upstream of the suction fan; and a filter supported by at least one of the housing and the dust container,