A compound having the structure of Formula (Ia): wherein: R 1 is H or C 1-6 alkyl; R 2 is H or C 1-6 alkyl; each R 3 is independently selected from C 1-6 alkyl, C 1-6 alkenyl, C 1-6 alkynyl, halogen, -CN, C 1-6 haloalkyl, C 1-6 aminoalkyl, heterocycloalkyl, -C 1-6 alkyl(heterocycloalkyl), heteroaryl, -SF 5, - NR 5 R 6, -OR 7, -CO 2 R 8, -C R 8, and -C NR 8 R 9, wherein heterocycloalkyl and -C 1-6 alkyl(heterocycloalkyl) are optionally substituted with one or two R 4; or two adjacent R 3 form a heterocycloalkyl ring, wherein the heterocycloalkyl ring and the heteroaryl ring are optionally substituted with one, two, or three R 4; each R 4 is independently selected from C 1-6 alkyl, C 1-6 haloalkyl, C 3-8 cycloalkyl, halogen, oxo, -CN, -CO 2 R 8, -C R 8, -C NR 8 R 9, -SO 2 R 8, -NR 9 C R 8, and -NR 9 SO 2 R 8; each R 5 and R 6 is independently selected from H, C 1-6 alkyl, C 1-6 haloalkyl, C 1-6 aminoalkyl, C 3-8 cycloalkyl, -C 1-6 alkyl(heterocycloalkyl), -C 1-6 alkyl-C (heterocycloalkyl), heterocycloalkyl, aryl, and heteroaryl; or R 5 and R 6, together with the nitrogen to which they are attached, form a heterocycloalkyl ring optionally substituted with one, two, or three R 10; each R 7 is independently selected from H, C 1-6 alkyl, C 1-6 haloalkyl, C 1-6 aminoalkyl, C 3-8 cycloalkyl, -C 1-6 alkyl(heterocycloalkyl), -C 1-6 alkyl-C (heterocycloalkyl), heterocycloalkyl, aryl, and heteroaryl, wherein heterocycloalkyl, aryl, and heteroaryl are optionally substituted with one or two groups selected from oxo, C 1-6 alkyl, C 1-6 haloalkyl, CO 2 H, and C NH 2; each R 8 and R 9 is independently selected from H, C 1-6 alkyl, C 1-6 haloalkyl, C 3-8 cycloalkyl, aryl, and heteroaryl; or R 8 and R 9, together with the nitrogen to which they are attached, form a heterocycloalkyl ring optionally substituted with one or two groups selected from C 1-6 alkyl, C 1-6 haloalkyl, CO 2 H, and C NH 2; each R 10 is independently selected from C 1-6 alkyl, C 3-8 cycloalkyl, C 1-6 haloalkyl, halogen, oxo, - CN, -CO 2 R 8, -C R 8, -C NR 8 R 9, -SO 2 R 8, -NR 9 C R 8, and -NR 9 SO 2 R 8; p is 0, 1, 2, 3, 4, or 5; n is 0 or 1; and m is 1 or 2; provided that when n is 0, then m is 2; and when n is 1, then m is 1; or a solvate, hydrate, tautomer, N -oxide, stereoisomer, or pharmaceutically acceptable salt thereof. R 1 is H or C 1-6 alkyl; R 2 is H or C 1-6 alkyl; each R 3 is independently selected from C 1-6 alkyl, C 1-6 alkenyl, C 1-6 alkynyl, halogen, -CN, C 1-6 haloalkyl, C 1-6 aminoalkyl, heterocycloalkyl, -C 1-6 alkyl(heterocycloalkyl), heteroaryl, -SF 5, - NR 5 R 6, -OR 7, -CO 2 R 8, -C R 8, and -C NR 8 R 9, wherein heterocycloalkyl and -C 1-6 alkyl(heterocycloalkyl) are optionally substituted with one or two R 4; or two adjacent R 3 form a heterocycloalkyl ring, wherein the heterocycloalkyl ring and the heteroaryl ring are optionally substituted with one, two, or three R 4; each R 4 is independently selected from C 1-6 alkyl, C 1-6 haloalkyl, C 3-8 cycloalkyl, halogen, oxo, -CN, -CO 2 R 8, -C R 8, -C NR 8 R 9, -SO 2 R 8, -NR 9 C R 8, and -NR 9 SO 2 R 8; each R 5 and R 6 is independently selected from H, C 1-6 alkyl, C 1-6 haloalkyl, C 1-6 aminoalkyl, C 3-8 cycloalkyl, -C 1-6 alkyl(heterocycloalkyl), -C 1-6 alkyl-C (heterocycloalkyl), heterocycloalkyl, aryl, and heteroaryl; or R 5 and R 6, together with the nitrogen to which they are attached, form a heterocycloalkyl ring optionally substituted with one, two, or three R 10; each R 7 is independently selected from H, C 1-6 alkyl, C 1-6 haloalkyl, C 1-6 aminoalkyl, C 3-8 cycloalkyl, -C 1-6 alkyl(heterocycloalkyl), -C 1-6 alkyl-C (heterocycloalkyl), heterocycloalkyl, aryl, and heteroaryl, wherein heterocycloalkyl, aryl, and heteroaryl are optionally substituted with one or two groups selected from oxo, C 1-6 alkyl, C 1-6 haloalkyl, CO 2 H, and C NH 2; each R 8 and R 9 is independently selected from H, C 1-6 alkyl, C 1-6 haloalkyl, C 3-8 cycloalkyl, aryl, and heteroaryl; or R 8 and R 9, together with the nitrogen to which they are attached, form a heterocycloalkyl ring optionally substituted with one or two groups selected from C 1-6 alkyl, C 1-6 haloalkyl, CO 2 H, and C NH 2; each R 10 is independently selected from C 1-6 alkyl, C 3-8 cycloalkyl, C 1-6 haloalkyl, halogen, oxo, - CN, -CO 2 R 8, -C R 8, -C NR 8 R 9, -SO 2 R 8, -NR 9 C R 8, and -NR 9 SO 2 R 8; p is 0, 1, 2, 3, 4, or 5; n is 0 or 1; and m is 1 or 2; provided that when n is 0, then m is 2; and when n is 1, then m is 1;