A mass spectrometry method, comprising: (i) preparing a mass filtering device of a mass spectrometer system to transmit therethrough ion species comprising a pre-determined range of mass-to-charge ratio ( m / z) values; (ii) transmitting a first batch of ion species to the mass filtering device and transmitting a subset of the first batch of ion species from the mass filtering device to an ion storage device of the mass spectrometer system and accumulating the subset of the first batch of ion species within the ion storage device, the transmitted subset of the first batch of ion species comprising m / z values within the predetermined range; (iii) transferring the accumulated subset of the first batch of ion species to a fragmentation cell of the mass spectrometer system, the fragmentation cell generating a first set of fragment-ion species from the subset of the first batch of ion species; (iv) transferring the first set of fragment-ion species to a mass analyzer of the mass spectrometer system and mass analyzing the first set of fragment-ion species using the mass analyzer; (v) concurrently with at least a portion of either the accumulating of the subset of the first batch of ion species within the ion storage device, the generating of the first set of fragment-ion species or the mass analyzing of the first set of fragment-ion species, preparing the mass filtering device to transmit therethrough ion species comprising a second pre-determined range of m / z values; and (vi) concurrently with at least a portion of either the generating of the first set of fragment-ion species or the mass analyzing of the first set of fragment-ion species, transmitting a second batch of ion species to the mass filtering device and transmitting a subset of the second batch of ion species from the mass filtering device to the ion storage device and accumulating the subset of the second batch of ion species within the ion storage device, the transmitted subset of the second batch of ion species comprising m / z values within the second predetermined range of m / z values; characterized in that the method further comprises: (vii) concurrently with at least a portion of the mass analyzing of the first set of fragment-ion species, preparing the mass filtering device to transmit therethrough ion species comprising a third pre-determined range of m / z values. (i) preparing a mass filtering device of a mass spectrometer system to transmit therethrough ion species comprising a pre-determined range of mass-to-charge ratio ( m / z) values; (ii) transmitting a first batch of ion species to the mass filtering device and transmitting a subset of the first batch of ion species from the mass filtering device to an ion storage device of the mass spectrometer system and accumulating the subset of the first batch of ion species within the ion storage device, the transmitted subset of the first batch of ion species comprising m / z values within the predetermined range; (iii) transferring the accumulated subset of the first batch of ion species to a fragmentation cell of the mass spectrometer system, the fragmentation cell generating a first set of fragment-ion species from the subset of the first batch of ion species; (iv) transferring the first set of fragment-ion species to a mass analyzer of the mass spectrometer system and mass analyzing the first set of fragment-ion species using the mass analyzer; (v) concurrently with at least a portion of either the accumulating of the subset of the first batch of ion species within the ion storage device, the generating of the first set of fragment-ion species or the mass analyzing of the first set of fragment-ion species, preparing the mass filtering device to transmit therethrough ion species comprising a second pre-determined range of m / z values; and (vi) concurrently with at least a portion of either the generating of the first set of fragment-ion species or the mass analyzing of the first set of fragment-ion species, transmitting a second batch of ion species to the mass filtering device and transmitting a subset of the second batch of ion species from the mass filtering device to the ion storage device and accumulating the subset of the second batch of ion species within the ion storage device, the transmitted subset of the second batch of ion species comprising m / z values within the second predetermined range of m / z values;