A method for determining the delamination risk of a plurality of pharmaceutical glass containers, each glass container of the plurality of the glass containers comprising: a glass body having a wall region with an interior surface and an exterior surface, a heel region, and a base region, wherein the interior surface of the glass container is formed by the interior surface of the glass body, and wherein the glass container has a CDR value of less than or equal to 6.0, the glass container has at least a class A2 base resistance or better according to ISO 695, the glass container has at least a type HGB2 hydrolytic resistance or better according to ISO 719, the glass container has Type 1 chemical durability according to USP <660>; and wherein CDR value calculation comprises the following steps: obtaining the plurality of glass containers; adding to each glass container of the plurality of the glass containers a solvent such that a volume of the solvent in each glass container comprises from greater than or equal to 5.0% by volume of the glass container to less than or equal to 50.0% by volume of the glass container; heating the plurality of glass containers to a temperature from 90 °C to 130 °C; cooling the plurality of glass containers to room temperature; removing and consolidating the solvent from the plurality of glass containers to obtain a consolidated solvent; titrating the consolidated solvent, wherein an amount of a titrant used in titrating the consolidated solvent is an as received titrant volume; etching each glass container of the plurality of glass containers by contacting at least the interior surface of the each glass container with an etchant, wherein the etching removes a layer of the interior surface of each glass container, the layer having a thickness from greater than or equal to 0.75 μm to less than or equal to 15 μm to obtain a plurality of etched glass containers; rinsing each etched glass container of the plurality of etched glass containers to remove residual etchant; adding to each etched glass container of the plurality of etched glass containers a second solvent such that a volume of the second solvent in each etched glass container comprises from greater than or equal to 5.0% by volume of the etched glass container to less than or equal to 50.0% by volume of the etched glass container; heating the plurality of etched glass containers to temperatures from 90 °C to 130 °C; cooling the plurality of etched glass containers to room temperature; removing and consolidating the second solvent from the plurality of etched glass containers to obtain an etched consolidated solvent; titrating the etched consolidated solvent, wherein an amount of a titrant used in titrating the etched consolidated solvent is an etched titrant volume; wherein the CDR of the plurality of glass containers comprises CDR = As Received Titrant Volume Etched Titrant Volume. the glass container has a CDR value of less than or equal to 6.0, the glass container has at least a class A2 base resistance or better according to ISO 695, the glass container has at least a type HGB2 hydrolytic resistance or better according to ISO 719, the glass container has Type 1 chemical durability according to USP <660>; and obtaining the plurality of glass containers; adding to each glass container of the plurality of the glass containers a solvent such that a volume of the solvent in each glass container comprises from greater than or equal to 5.0% by volume of the glass container to less than or equal to 50.0% by volume of the glass container; heating the plurality of glass containers to a temperature from 90 °C to 130 °C; cooling the plurality of glass containers to room temperature; removing and consolidating the solvent from the plurality of glass containers to obtain a consolidated solvent; titrating the consolidated solvent, wherein an amount of a titrant used in titrating the consolidated solvent is an as received titrant volume; etching each glass container of the plurality of glass containers by contacting at least the interior surface of the each glass container with an etchant, wherein the etching removes a layer of the interior surface of each glass container, the layer having a thickness from greater than or equal to 0.75 μm to less than or equal to 15 μm to obtain a plurality of etched glass containers; rinsing each etched glass container of the plurality of etched glass containers to remove residual etchant; adding to each etched glass container of the plurality of etched glass containers a second solvent such that a volume of the second solvent in each etched glass container comprises from greater than or equal to 5.0% by volume of the etched glass container to less than or equal to 50.0% by volume of the etched glass container; heating the plurality of etched glass containers to temperatures from 90 °C to 130 °C; cooling the plurality of etched glass containers to room temperature; removing and consolidating the second solvent from the plurality of etched glass containers to obtain an etched consolidated solvent; titrating the etched consolidated solvent, wherein an amount of a titrant used in titrating the etched consolidated solvent is an etched titrant volume; wherein the CDR of the plurality of glass containers comprises CDR = As Received Titrant Volume Etched Titrant Volume.