An apparatus for nucleic acid sequencing, comprising: a base-detection device in a detection site, the base-detection device being configured to detect bases of a portion of a nucleic acid strand at the detection site; a conveying device, configured to extend the nucleic acid strand and to cause the extended nucleic acid strand to slide through the detection site along a path; a reading circuit; and a control unit; wherein the base-detection device comprises a plurality of field-effect nanowire detectors, arranged in respective positions (P1, P2,..., PK) along the path and each comprising a respective nanowire and nucleic acid probes, the nucleic acid probes being defined by respective base sequences and being fixed each to the respective nanowire; wherein the reading circuit is configured to determine a state of conduction of each of the nanowire detectors and to provide a succession of read signals indicating base sequences present in the nucleic acid strand and corresponding to respective nucleic acid probes of respective nanowire detectors; characterized in that the control unit is configured to reconstruct an effective base sequence forming the nucleic acid strand on the basis of the read signals supplied by the reading circuit and of the respective positions (P1, P2,..., PK) of the nanowire detectors, wherein the control unit is further configured to convert a raw base sequence, defined by the succession of the read signals, into the effective base sequence by translating base sequences corresponding to each nanowire detector, which has positively made a detection, by a number of positions such as to compensate a detection delay due to a distance between an actual position of the nanowire detector, which has positively made the detection, and a reference position of a reference nanowire detector. a base-detection device in a detection site, the base-detection device being configured to detect bases of a portion of a nucleic acid strand at the detection site; a conveying device, configured to extend the nucleic acid strand and to cause the extended nucleic acid strand to slide through the detection site along a path; a reading circuit; and a control unit; wherein the base-detection device comprises a plurality of field-effect nanowire detectors, arranged in respective positions (P1, P2,..., PK) along the path and each comprising a respective nanowire and nucleic acid probes, the nucleic acid probes being defined by respective base sequences and being fixed each to the respective nanowire; wherein the reading circuit is configured to determine a state of conduction of each of the nanowire detectors and to provide a succession of read signals indicating base sequences present in the nucleic acid strand and corresponding to respective nucleic acid probes of respective nanowire detectors; characterized in that the control unit is configured to reconstruct an effective base sequence forming the nucleic acid strand on the basis of the read signals supplied by the reading circuit and of the respective positions (P1, P2,..., PK) of the nanowire detectors, wherein the control unit is further configured to convert a raw base sequence, defined by the succession of the read signals, into the effective base sequence by translating base sequences corresponding to each nanowire detector, which has positively made a detection, by a number of positions such as to compensate a detection delay due to a distance between an actual position of the nanowire detector, which has positively made the detection, and a reference position of a reference nanowire detector.