A compound selected from the group consisting of: 3,7-dichloro-10-((3R,4R)-3-hydroxyazepan-4-yl)-10H-phenothiazine 5,5-dioxide, 3,7-dichloro-10-((3S,4S)-3-hydroxyazepan-4-yl)-10H-phenothiazine 5,5-dioxide, (3R,4R)-4-(3,6-dichloro-9H-carbazol-9-yl)azepan-3-ol, (3S,4S)-4-(3,6-dichloro-9H-carbazol-9-yl)azepan-3-ol, (3R,4R)-4-[3,6-bis(trifluoromethyl)-9H-carbazol-9-yl]azepan-3-ol, (3S,4S)-4-[3,6-bis(trifluoromethyl)-9H-carbazol-9-yl]azepan-3-ol, (3R,4R)-4-[4-methylsulfonyl-3,6-bis(trifluoromethyl)carbazol-9-yl]azepan-3-ol, (3S,4S)-4-[4-methylsulfonyl-3,6-bis(trifluoromethyl)carbazol-9-yl]azepan-3-ol, (3R,4R)-4-[2-methylsulfonyl-3,6-bis(trifluoromethyl)carbazol-9-yl]azepan-3-ol, (3S,4S)-4-[2-methylsulfonyl-3,6-bis(trifluoromethyl)carbazol-9-yl]azepan-3-ol, (3S,4S)-4-(3,6-dichloro-1-methoxy-9H-carbazol-9-yl)azepan-3-ol, (3R,4R)-4-(3,6-dichloro-1-methoxy-9H-carbazol-9-yl)azepan-3-o,l (3R,4R)-4-(3,6-dichloro-2-methoxy-9H-carbazol-9-yl)azepan-3-ol, (3S,4S)-4-(3,6-dichloro-2-methoxy-9H-carbazol-9-yl)azepan-3-ol, (3R,4R)-4-(3,7-dichloro-10H-phenoxazin-10-yl)azepan-3-ol, (3S,4S)-4-(3,7-dichloro-10H-phenoxazin-10-yl)azepan-3-ol, (3R,4R)-4-[3,6-bis(trifluoromethyl)pyrido[2,3-b]indol-9-yl]azepan-3-ol, (3S,4S)-4-[3,6-bis(trifluoromethyl)pyrido[2,3-b]indol-9-yl]azepan-3-ol, (3R,4R)-4-[3,6-bis(trifluoromethyl)pyrido[3,4-b]indol-9-yl]azepan-3-ol, (3S,4S)-4-[3,6-bis(trifluoromethyl)pyrido[3,4-b]indol-9-yl]azepan-3-ol, (3R,4R)-4-(2,8-bis(trifluoromethyl)-5H-pyrido[3,2-b]indol-5-yl)azepan-3-ol, (3S,4S)-4-(2,8-bis(trifluoromethyl)-5H-pyrido[3,2-b]indol-5-yl)azepan-3-ol, (3R,4R)-4-(7-methoxy-2,8-bis(trifluoromethyl)-5H-pyrido[3,2-b]indol-5-yl)azepan-3-ol, (3S,4S)-4-(7-methoxy-2,8-bis(trifluoromethyl)-5H-pyrido[3,2-b]indol-5-yl)azepan-3-ol, (3R,4R)-4-(8-chloro-6-methoxy-2-(trifluoromethyl)-5H-pyrido[3,2-b]indol-5-yl)azepan-3-ol, (3S,4S)-4-(8-chloro-6-methoxy-2-(trifluoromethyl)-5H-pyrido[3,2-b]indol-5-yl)azepan-3-ol, (3R,4R)-4-(8-chloro-2-(trifluoromethyl)-5H-pyrimido[5,4-b]indol-5-yl)azepan-3-ol, (3S,4S)-4-(8-chloro-2-(trifluoromethyl)-5H-pyrimido[5,4-b]indol-5-yl)azepan-3-ol, (3R,4R)-4-(2,8-bis(trifluoromethyl)-5H-pyrrolo[2,3-b:4,5-b']dipyridin-5-yl)azepan-3-ol, (3S,4S)-4-(2,8-bis(trifluoromethyl)-5H-pyrrolo[2,3-b:4,5-b']dipyridin-5-yl)azepan-3-ol, (3R,4R)-4-((8-chloro-5H-pyrimido[5,4-b]indol-4-yl)amino)azepan-3-ol, (3R,4R)-4-(3-chloro-6-nitro-carbazol-9-yl)azepan-3-ol, (5R,6R)-5-(3,6-dichloro-9H-carbazol-9-yl)-6-hydroxyazepan-2-one, (3R,4R)-4-[8-chloro-2-(trifluoromethyl)pyrimido[5,4-b]indol-5-yl]-7-methyl-azepan-3-ol, (8-chloro-5-[(3R,4R)-3-hydroxyazepan-4-yl]-3H-pyrimido[5,4-b]indol-4-one, (3R,4R)-4-(8-chloro-4-methoxy-pyrimido[5,4-b]indol-5-yl)azepan-3-ol and the pharmaceutically acceptable tautomers, salts, solvates and stereoisomers thereof 3,7-dichloro-10-((3R,4R)-3-hydroxyazepan-4-yl)-10H-phenothiazine 5,5-dioxide, 3,7-dichloro-10-((3S,4S)-3-hydroxyazepan-4-yl)-10H-phenothiazine 5,5-dioxide, (3R,4R)-4-(3,6-dichloro-9H-carbazol-9-yl)azepan-3-ol, (3S,4S)-4-(3,6-dichloro-9H-carbazol-9-yl)azepan-3-ol, (3R,4R)-4-[3,6-bis(trifluoromethyl)-9H-carbazol-9-yl]azepan-3-ol, (3S,4S)-4-[3,6-bis(trifluoromethyl)-9H-carbazol-9-yl]azepan-3-ol, (3R,4R)-4-[4-methylsulfonyl-3,6-bis(trifluoromethyl)carbazol-9-yl]azepan-3-ol, (3S,4S)-4-[4-methylsulfonyl-3,6-bis(trifluoromethyl)carbazol-9-yl]azepan-3-ol, (3R,4R)-4-[2-methylsulfonyl-3,6-bis(trifluoromethyl)carbazol-9-yl]azepan-3-ol, (3S,4S)-4-[2-methylsulfonyl-3,6-bis(trifluoromethyl)carbazol-9-yl]azepan-3-ol, (3S,4S)-4-(3,6-dichloro-1-methoxy-9H-carbazol-9-yl)azepan-3-ol, (3R,4R)-4-(3,6-dichloro-1-methoxy-9H-carbazol-9-yl)azepan-3-o,l (3R,4R)-4-(3,6-dichloro-2-methoxy-9H-carbazol-9-yl)azepan-3-ol, (3S,4S)-4-(3,6-dichloro-2-methoxy-9H-carbazol-9-yl)azepan-3-ol, (3R,4R)-4-(3,7-dichloro-10H-phenoxazin-10-yl)azepan-3-ol, (3S,4S)-4-(3,7-dichloro-10H-phenoxazin-10-yl)azepan-3-ol, (3R,4R)-4-[3,6-bis(trifluoromethyl)pyrido[2,3-b]indol-9-yl]azepan-3-ol, (3S,4S)-4-[3,6-bis(trifluoromethyl)pyrido[2,3-b]indol-9-yl]azepan-3-ol, (3R,4R)-4-[3,6-bis(trifluoromethyl)pyrido[3,4-b]indol-9-yl]azepan-3-ol, (3S,4S)-4-[3,6-bis(trifluoromethyl)pyrido[3,4-b]indol-9-yl]azepan-3-ol, (3R,4R)-4-(2,8-bis(trifluoromethyl)-5H-pyrido[3,2-b]indol-5-yl)azepan-3-ol, (3S,4S)-4-(2,8-bis(trifluoromethyl)-5H-pyrido[3,2-b]indol-5-yl)azepan-3-ol, (3R,4R)-4-(7-methoxy-2,8-bis(trifluoromethyl)-5H-pyrido[3,2-b]indol-5-yl)azepan-3-ol, (3S,4S)-4-(7-methoxy-2,8-bis(trifluoromethyl)-5H-pyrido[3,2-b]indol-5-yl)azepan-3-ol, (3R,4R)-4-(8-chloro-6-methoxy-2-(trifluoromethyl)-5H-pyrido[3,2-b]indol-5-yl)azepan-3-ol, (3S,4S)-4-(8-chloro-6-methoxy-2-(trifluoromethyl)-5H-pyrido[3,2-b]indol-5-yl)azepan-3-ol, (3R,4R)-4-(8-chloro-2-(trifluoromethyl)-5H-pyrimido[5,4-b]indol-5-yl)azepan-3-ol, (3S,4S)-4-(8-chloro-2-(trifluoromethyl)-5H-pyrimido[5,4-b]indol-5-yl)azepan-3-ol, (3R,4R)-4-(2,8-bis(trifluoromethyl)-5H-pyrrolo[2,3-b:4,5-b']dipyridin-5-yl)azepan-3-ol, (3S,4S)-4-(2,8-bis(trifluoromethyl)-5H-pyrrolo[2,3-b:4,5-b']dipyridin-5-yl)azepan-3-ol, (3R,4R)-4-((8-chloro-5H-pyrimido[5,4-b]indol-4-yl)amino)azepan-3-ol, (3R,4R)-4-(3-chloro-6-nitro-carbazol-9-yl)azepan-3-ol, (5R,6R)-5-(3,6-dichloro-9H-carbazol-9-yl)-6-hydroxyazepan-2-one, (3R,4R)-4-[8-chloro-2-(trifluoromethyl)pyrimido[5,4-b]indol-5-yl]-7-methyl-azepan-3-ol, (8-chloro-5-[(3R,4R)-3-hydroxyazepan-4-yl]-3H-pyrimido[5,4-b]indol-4-one, (3R,4R)-4-(8-chloro-4-methoxy-pyrimido[5,4-b]indol-5-yl)azepan-3-ol