mhurhangee/ep-ind-claims huggingface dataset:
A method for amplifying nucleic acids, comprising (a) providing (i) an array of amplification sites having one or more capture agents, and (ii) an amplification reagent comprising a solution comprising a plurality of different target nucleic acids, wherein the number of the different target nucleic acids in the solution exceeds the number of amplification sites in the array, wherein the different target nucleic acids have fluidic access to the plurality of amplification sites, and wherein each of the amplification sites is occupied by several nucleic acids of the plurality of different nucleic acids prior to: (b) reacting the amplification reagent with the array of amplification sites, such that a plurality of amplification sites each comprises a clonal population of amplicons from an individual target nucleic acid from the solution, wherein the reacting comprises (i) producing a first amplicon from an individual target nucleic acid that transports to each of the amplification sites, and (ii) producing subsequent amplicons from the individual target nucleic acid that transports to each of the amplification sites or from the first amplicon, wherein the average rate at which the subsequent amplicons are generated at the amplification sites exceeds the average rate at which the first amplicon is generated at the amplification sites; wherein each of the amplification sites comprises a plurality of primers that are used to produce the amplicons in (b); and wherein the producing of the first amplicon comprises converting at least one of the primers from a non-extendible state to an extendible state. (a) providing (i) an array of amplification sites having one or more capture agents, and (ii) an amplification reagent comprising a solution comprising a plurality of different target nucleic acids, wherein the number of the different target nucleic acids in the solution exceeds the number of amplification sites in the array, wherein the different target nucleic acids have fluidic access to the plurality of amplification sites, and wherein each of the amplification sites is occupied by several nucleic acids of the plurality of different nucleic acids prior to: (i) an array of amplification sites having one or more capture agents, and (ii) an amplification reagent comprising a solution comprising a plurality of different target nucleic acids, (b) reacting the amplification reagent with the array of amplification sites, such that a plurality of amplification sites each comprises a clonal population of amplicons from an individual target nucleic acid from the solution,
A pedestal comprising: a frame portion on which a plurality of legs coupled to a bottom surface of a laundry processor are seatable; a housing configured to surround the frame portion; a plurality of seat portions (20a, 20b, 20c, 20d) recessively formed on an upper portion of the housing in a body with the housing to form a plurality of leg seat points, and characterized in that: the plurality of seat portions form openings to expose a part of the frame portion to the outside of the housing, and the plurality of seat portions are formed to be bent so that the seat portions become narrower in a direction from an upper portion of the housing to an inside of the housing. a frame portion on which a plurality of legs coupled to a bottom surface of a laundry processor are seatable; a housing configured to surround the frame portion; a plurality of seat portions (20a, 20b, 20c, 20d) recessively formed on an upper portion of the housing in a body with the housing to form a plurality of leg seat points, and characterized in that: the plurality of seat portions form openings to expose a part of the frame portion to the outside of the housing, and the plurality of seat portions are formed to be bent so that the seat portions become narrower in a direction from an upper portion of the housing to an inside of the housing. the plurality of seat portions form openings to expose a part of the frame portion to the outside of the housing, and the plurality of seat portions are formed to be bent so that the seat portions become narrower in a direction from an upper portion of the housing to an inside of the housing.
A method for selecting one or more antibodies with degradation stability comprising the following steps a) providing two or more antibodies, b) determining for each Asp and Asn residue in an antibody Fv region the conformational flexibility of the C α -atom using a homology model ensemble, c) determining for each Asp and Asn residue in an antibody Fv region the size of the amino acid residue C-terminal to the Asp or Asn residue, d) selecting one or more antibodies in which the C α -atom is conformationally inflexible and the Asp or Asn has a C-terminal amino acid residue with a solvent accessible surface area of 111 Å2 or more, wherein the conformational flexibility is the root mean square deviation (RMSD) of the respective Asn/Asp residues' C α -atoms in the homology model ensemble, and wherein i) conformational inflexible is a RMSD of 0.01 Å or less, ii) conformational flexible is a RMSD of more than 0.01 Å, iii) conformational moderate flexible is a RMSD between 0.145 Å and 0.485 Å, and iv) conformational highly flexible is a RMSD of more than 0.485 Å, and thereby selecting one or more antibodies with degradation stability. a) providing two or more antibodies, b) determining for each Asp and Asn residue in an antibody Fv region the conformational flexibility of the C α -atom using a homology model ensemble, c) determining for each Asp and Asn residue in an antibody Fv region the size of the amino acid residue C-terminal to the Asp or Asn residue, d) selecting one or more antibodies in which the C α -atom is conformationally inflexible and the Asp or Asn has a C-terminal amino acid residue with a solvent accessible surface area of 111 Å2 or more, i) conformational inflexible is a RMSD of 0.01 Å or less, ii) conformational flexible is a RMSD of more than 0.01 Å, iii) conformational moderate flexible is a RMSD between 0.145 Å and 0.485 Å, and iv) conformational highly flexible is a RMSD of more than 0.485 Å,
A compressible layered element for realising a varnishing blanket applicable to a cylinder of an offset printing machine for transfer of an overprint onto the paper, characterised in that it comprises a first compressible layer and a second compressible layer exhibiting a flexible adhesion at the interface (4, 5), said first compressible layer exhibiting a second face opposite the interface (4, 5) and exhibiting first adhesive means for adhesion to a layered transfer element of said overprint onto the paper, said second compressible layer exhibiting a second face opposite the interface (4, 5) and exhibiting second adhesive means for adhesion to a layered support element, said adhesion to the interface (4, 5) between said first and second compressible layer (2, 3) being weaker than both the adhesion capability of said first compressible layer to said layered transfer element guaranteed by said first adhesive means and the adhesion capability of said second compressible layer to said layered support element guaranteed by said second adhesive means.
A method performed by a terminal device for uplink transmission in a wireless communication system, comprising: - obtaining, from a network node, configuration on Scheduling Request, SR, transmission corresponding tc a Logical Channel Group, LCG; - determining (120, 520) a SR transmission mode according to the obtained configuration on SR transmission, wherein the determined SR transmission mode is selected among at least two SR transmission modes, one of which is an SR transmission diversity mode in which the terminal device transmits the SR signal across multiple carriers, and wherein the at least two SR transmission modes are comprised in the configuration on SR transmission together with a condition for switching between SR transmission modes; and - transmitting (130, 530) at least one SR signal to the network node according to the determined SR transmission mode, asking for resource for uplink transmission. - obtaining, from a network node, configuration on Scheduling Request, SR, transmission corresponding tc a Logical Channel Group, LCG; - determining (120, 520) a SR transmission mode according to the obtained configuration on SR transmission, wherein the determined SR transmission mode is selected among at least two SR transmission modes, one of which is an SR transmission diversity mode in which the terminal device transmits the SR signal across multiple carriers, and wherein the at least two SR transmission modes are comprised in the configuration on SR transmission together with a condition for switching between SR transmission modes; and - transmitting (130, 530) at least one SR signal to the network node according to the determined SR transmission mode, asking for resource for uplink transmission.
Method for operating a motor vehicle, comprising a plurality of vehicle systems having at least one operating parameter which can be set and at least one sensor for determining driving parameters describing the driving situation and/or the surroundings of the motor vehicle, characterised in that, upon actuation of an operating element (5, 6), at least some of the current driving parameters describing the current driving situation and at least some of the current operating parameters of vehicle systems which affect a plurality of vehicle systems are stored as a set of data, whereupon, in the further course, in at least one further driving situation, the operating parameters are set by comparing the driving situation at the time of storage with the further driving situation such that the property state at the time when the set of data was recorded is at least approximately restored with regard to at least one driving property which can be perceived by the driver.
An automated system for processing vessels containing biological samples, the automated system comprising: - a plurality of vessel holders for the vessels containing biological samples - a transport medium for transporting the vessel holders within the automated system - a work cell for processing the vessels containing biological samples - a storage module for empty members of the plurality of vessel holders, wherein the storage module is connected to the transport medium via an empty vessel holder transfer unit for retrieving empty vessel holders from the transport medium and introducing them into the storage module, or retrieving empty vessel holders from the storage module and placing them in or on the transport medium - a robotic manipulator for engaging and/or disengaging the vessels containing biological samples with the empty members of the plurality of vessel holders - a control unit for controlling the automated system - an empty vessel holder detection unit for detecting empty vessel holders in or on the transport medium, the empty vessel holder detection unit comprising an empty vessel holder detector for discriminating between filled and empty vessel holders wherein the empty vessel holder detector is configured to monitor the presence of any empty vessel holder circulating in or on the transport medium, and a transfer initiator configured to initiate the introduction or re-introduction of an empty vessel holder detected in or on the transport medium into the storage module by the empty vessel holder transfer unit. - a plurality of vessel holders for the vessels containing biological samples - a transport medium for transporting the vessel holders within the automated system - a work cell for processing the vessels containing biological samples - a storage module for empty members of the plurality of vessel holders, wherein the storage module is connected to the transport medium via an empty vessel holder transfer unit for retrieving empty vessel holders from the transport medium and introducing them into the storage module, or retrieving empty vessel holders from the storage module and placing them in or on the transport medium - a robotic manipulator for engaging and/or disengaging the vessels containing biological samples with the empty members of the plurality of vessel holders - a control unit for controlling the automated system - an empty vessel holder detection unit for detecting empty vessel holders in or on the transport medium, the empty vessel holder detection unit comprising an empty vessel holder detector for discriminating between filled and empty vessel holders wherein the empty vessel holder detector is configured to monitor the presence of any empty vessel holder circulating in or on the transport medium, and a transfer initiator configured to initiate the introduction or re-introduction of an empty vessel holder detected in or on the transport medium into the storage module by the empty vessel holder transfer unit.
A method of separating glycosaminoglycan from one or more proteins in a sample, the method comprising: subjecting a sample to size-exclusion chromatography using a mobile phase having a pH of less than 3.0; wherein said sample comprises one or more recombinant proteins; and wherein the mobile phase comprises a salt. subjecting a sample to size-exclusion chromatography using a mobile phase having a pH of less than 3.0; wherein said sample comprises one or more recombinant proteins; and wherein the mobile phase comprises a salt.
An imaging probe for insertion into bodily lumens and cavities for imaging an interior of said bodily lumens and cavities, comprising: an elongate hollow shaft having a longitudinal axis having distal and proximal end sections and an elongate midsection, an imaging conduit, an imaging assembly being located in said elongate hollow shaft remote from said proximal end section, said imaging assembly being connected to a first end of said imaging conduit such that rotation of said imaging conduit causes rotation of said imaging assembly, said imaging conduit extending through the elongate hollow shaft and being connectable through a connector or adaptor at a second end thereof to an image processing and display system through the proximal end section, said connector or adapter being configured to couple rotary and non-rotary components of the imaging probe, said imaging conduit comprising at least one optical waveguide each having a distal end and said imaging assembly including an optical emitter / collector including light directing and receiving means associated with said distal end of said at least one optical waveguide for directing light imaging energy out of a distal end of said at least one optical waveguide and receiving reflected light imaging energy signals and directing said received reflected light imaging energy signals back to said image processing and display system, said light directing and receiving means being one or more mirrors or one or more prisms for deflecting the path of light imaging energy, said imaging assembly including an ultrasound transducer comprising a substrate, said transducer having a back surface and comprising a backing on said back surface adapted to attenuate signals generated from the back surface on the substrate, and said ultrasound transducer being adapted to emit and receive ultrasound imaging energy and said imaging conduit including an electrical conductor for electrically coupling the ultrasound transducer to an ultrasound signal generator and said image processing and display system; wherein at least a part of said light directing and receiving means is in, or is within, or is located in/within, or is contained in/within, or resides in/within said backing.
A photoconductive member comprised of a self-healing composite coating comprising a polymer matrix, a photoconductive component, a healing material encapsulated within nano- or microcapsules which are dispersed in the self-healing composite coating, and a catalyst, wherein said healing material is capable of repairing physical damage to the photoconductive member when the capsule ruptures, said healing material being selected from monomers, oligomers and prepolymers capable of forming a polymer, wherein said catalyst accelerates the polymerization of the healing material and comprises at least one member selected from the group consisting of transition metal catalysts, ROMP catalysts, and Lewis acid catalysts, and wherein said catalyst is distributed within the self-healing composite coating, or is embedded on the surface of the capsules, or is encapsulated in nano- or microcapsules.
A dry analytical element for the measurement of a high density lipoprotein cholesterol, which has at least one layer comprising an nonionic surfactant of 3 to 22 g/m 2, a buffer of 0.1 to 40 mmol/m 2, dextran sulfate with a molecular weight of 36,000 to 50,000, a divalent metal ion and reagents for measuring high density lipoprotein cholesterol, on a support.
An apparatus for water treatment comprising: means for removing soluble ingredients contained in water; means for adsorbing ions with a porous formed article as an adsorbent, wherein the porous formed article comprises fibrils, where fibril refers to a fibrous structure which contains an organic polymer resin and forms a three-dimensionally continuous network structure on the outer surface and the inside of the formed article, wherein the fibrils form communicating pores opening at the outer surface of the article, wherein there are cavities in the interior of the fibrils, and at least a part of said cavities opens at the surface of the fibril, and wherein the opening ratio at the outer surface of the formed article is in the range of 10 to 90%, the opening ratio referring to the ratio of the total opening area of all pores with respect to an area of a visual field shown when the surface is observed with a scanning electron microscope; wherein the diameter of the opening at the outer surface of the formed article is in the range of 0.005 to 100 μm; and an inorganic ion adsorbing material in the form of a powder, which is supported on the outer surface of the fibril and on the surface of inner cavities of the fibril, wherein said means for adsorbing ions with a porous formed article as an adsorbent is not included in said means for removing ingredients contained in water. means for removing soluble ingredients contained in water; means for adsorbing ions with a porous formed article as an adsorbent, wherein the porous formed article comprises fibrils, where fibril refers to a fibrous structure which contains an organic polymer resin and forms a three-dimensionally continuous network structure on the outer surface and the inside of the formed article, wherein the fibrils form communicating pores opening at the outer surface of the article, wherein there are cavities in the interior of the fibrils, and at least a part of said cavities opens at the surface of the fibril, and wherein the opening ratio at the outer surface of the formed article is in the range of 10 to 90%, the opening ratio referring to the ratio of the total opening area of all pores with respect to an area of a visual field shown when the surface is observed with a scanning electron microscope; wherein the diameter of the opening at the outer surface of the formed article is in the range of 0.005 to 100 μm; and an inorganic ion adsorbing material in the form of a powder, which is supported on the outer surface of the fibril and on the surface of inner cavities of the fibril, wherein said means for adsorbing ions with a porous formed article as an adsorbent is not included in said means for removing ingredients contained in water.
An implant comprising: a base material; and a carbon thin film which is formed on a surface of the base material, and contains silicon, wherein the carbon thin film contains a C-C component in which carbon atoms are bonded, and a SiC component in which carbon and silicon atoms are bonded, an atomic ratio of the SiC component is 0.06 or higher and 0.5 or lower, and an atomic ratio of the SiO 2 component [SiO 2]/([Si]+) is 0.05 or lower. a base material; and a carbon thin film which is formed on a surface of the base material, and contains silicon, wherein the carbon thin film contains a C-C component in which carbon atoms are bonded, and a SiC component in which carbon and silicon atoms are bonded, an atomic ratio of the SiC component is 0.06 or higher and 0.5 or lower, and an atomic ratio of the SiO 2 component [SiO 2]/([Si]+) is 0.05 or lower.
Electro-optical circuit with an optical transmission path, having • an electro-optical assembly with an optical transmitter element and/or an optical receiver element, which is mounted on a mounting surface of a carrier component, • a circuit carrier with a mounting side and with an embedded optical waveguide, which is exposed with an end face in a cutout introduced in the mounting side, and • an optical interface between the electro-optical assembly mounted on the circuit carrier and the optical waveguide, wherein the optical transmitter element and/or the optical receiver element is mounted on the carrier component with an alignment of its respective optical axis parallel to the mounting surface, wherein the optical assembly is mounted on the circuit carrier with the mounting surface facing toward the mounting side, wherein the optical transmitter element and/or the optical receiver element projects into the cutout and forms an optical axis with the exposed optical waveguide, wherein first contact surfaces are embodied on the mounting surface of the carrier component, on which first contact surfaces the optical transmitter element and/or the optical receiver element is electrically contacted, wherein second contact surfaces are provided on the mounting surface, which second contact surfaces are electrically connected to the first contact surfaces, and are electrically connected to third contact surfaces on the mounting side of the circuit carrier and wherein the second contact surfaces are distributed symmetrically around the optical transmitter element and/or the optical receiver element. • an electro-optical assembly with an optical transmitter element and/or an optical receiver element, which is mounted on a mounting surface of a carrier component, • a circuit carrier with a mounting side and with an embedded optical waveguide, which is exposed with an end face in a cutout introduced in the mounting side, and • an optical interface between the electro-optical assembly mounted on the circuit carrier and the optical waveguide, wherein the optical assembly is mounted on the circuit carrier with the mounting surface facing toward the mounting side, wherein the optical transmitter element and/or the optical receiver element projects into the cutout and forms an optical axis with the exposed optical waveguide, wherein first contact surfaces are embodied on the mounting surface of the carrier component, on which first contact surfaces the optical transmitter element and/or the optical receiver element is electrically contacted, wherein second contact surfaces are provided on the mounting surface, which second contact surfaces are electrically connected to the first contact surfaces, and are electrically connected to third contact surfaces on the mounting side of the circuit carrier and wherein the second contact surfaces are distributed symmetrically around the optical transmitter element and/or the optical receiver element.