mhurhangee/ep-ind-claims huggingface dataset:
A compound represented by the following Formula I, its individual enantiomers, its individual diastereoisomers, its hydrates, its solvates, its crystal forms, its individual tautomers or a pharmaceutically acceptable salt thereof, wherein: n = 1-3, preferably 1 or 2; R 1 is selected from the group consisting of aryl, arylalkyl, heteroaryl and heteroarylalkyl, each of which can be optionally substituted; R 3 and R 4 are independently selected from H and the group consisting of alkyl, aryl, arylalkyl, heteroaryl and heteroarylalkyl, each of which can be optionally substituted; R 2 is selected the group consisting of aryl, arylalkyl, heteroaryl and heteroarylalkyl, each of which is substituted; wherein any two of R 1, R 2, R 3 and R 4 may be joined together to form a ring; R 4 is preferably H; and X is -CH 2 -. n = 1-3, preferably 1 or 2; R 1 is selected from the group consisting of aryl, arylalkyl, heteroaryl and heteroarylalkyl, each of which can be optionally substituted; R 3 and R 4 are independently selected from H and the group consisting of alkyl, aryl, arylalkyl, heteroaryl and heteroarylalkyl, each of which can be optionally substituted; R 2 is selected the group consisting of aryl, arylalkyl, heteroaryl and heteroarylalkyl, each of which is substituted; wherein any two of R 1, R 2, R 3 and R 4 may be joined together to form a ring; R 4 is preferably H; and X is -CH 2 -.
A method for extracting three dimensional object model features from a database of object models with different shapes and reconstructing the object models from the extracted features comprising the steps of: - collecting existing object models in a database, characterized by, - transforming the object models' shapes into voxel space by embedding an object models' shape in a structure of a specified number of voxel-boxes, - checking for all voxels if a voxel-box is crossed by the embedded object models' shape, - identifying crossed voxel-boxes and voxel-boxes that are not crossed by the embedded object models' shape, - deriving a vector for each embedded object model, the vector's size corresponding to the number of all voxel-boxes, the values corresponding to a set value of the respective voxel which depends on whether the voxel is crossed by the design or not, - gathering the derived vectors in a matrix - performing a computational algorithm on said matrix to extract object features, wherein the computational algorithm is a non-negative matrix factorization algorithm with orthogonality constraints on the base vectors generated by the non negative matrix factorization algorithm and sparseness constraints on the base vectors and the coefficients of the coefficient matrix generated by the non-negative matrix factorization algorithm. - collecting existing object models in a database, characterized by, - transforming the object models' shapes into voxel space by embedding an object models' shape in a structure of a specified number of voxel-boxes, - checking for all voxels if a voxel-box is crossed by the embedded object models' shape, - identifying crossed voxel-boxes and voxel-boxes that are not crossed by the embedded object models' shape, - deriving a vector for each embedded object model, the vector's size corresponding to the number of all voxel-boxes, the values corresponding to a set value of the respective voxel which depends on whether the voxel is crossed by the design or not, - gathering the derived vectors in a matrix - performing a computational algorithm on said matrix to extract object features, wherein the computational algorithm is a non-negative matrix factorization algorithm with orthogonality constraints on the base vectors generated by the non negative matrix factorization algorithm and sparseness constraints on the base vectors and the coefficients of the coefficient matrix generated by the non-negative matrix factorization algorithm.
A surgical stapling device comprising: a handle assembly; a body portion extending distally from the handle assembly; a head portion including an anvil assembly and a shell assembly, the anvil assembly including an anvil head and an anvil center rod defining a longitudinal bore, the shell assembly supporting a plurality of staples, the anvil assembly being movable in relation to the shell assembly between spaced and approximated positions; an approximation mechanism (22, 32) including an anvil retainer for supporting the anvil assembly, the anvil retainer including an elongated distal extension dimensioned to be telescopingly received in the longitudinal bore of the anvil center rod, whereby the anvil assembly is removably secured to the anvil retainer characterized in that: the combined length of the anvil center rod and the elongated distal extension is greater than 114.3mm such that the elongated distal extension is of a length to allow telescoping of the elongated distal extension with the anvil center rod without obstructing visibility of a surgical site. a handle assembly; a body portion extending distally from the handle assembly; a head portion including an anvil assembly and a shell assembly, the anvil assembly including an anvil head and an anvil center rod defining a longitudinal bore, the shell assembly supporting a plurality of staples, the anvil assembly being movable in relation to the shell assembly between spaced and approximated positions; an approximation mechanism (22, 32) including an anvil retainer for supporting the anvil assembly, the anvil retainer including an elongated distal extension dimensioned to be telescopingly received in the longitudinal bore of the anvil center rod, whereby the anvil assembly is removably secured to the anvil retainer characterized in that: the combined length of the anvil center rod and the elongated distal extension is greater than 114.3mm such that the elongated distal extension is of a length to allow telescoping of the elongated distal extension with the anvil center rod without obstructing visibility of a surgical site. the combined length of the anvil center rod and the elongated distal extension is greater than 114.3mm such that the elongated distal extension is of a length to allow telescoping of the elongated distal extension with the anvil center rod without obstructing visibility of a surgical site.
A method of sharing content of an electronic device, the method comprising: storing, in the electronic device, a list of contents to be shared between the electronic device and another device (S200; S300), such that the contents to be shared are shared via at least one of a plurality of networks, each network comprising an access point, the electronic device and the other device, such that the electronic device and the other device are connected to the access point in order to be connected to one another, wherein the list of contents to be shared matches the access point, such that the list of contents to be shared is determined based on the access point; and setting, in the electronic device, contents included in the list of contents to be shared as shared contents in response to the electronic device being connected (S210; S320) to a given network of the plurality of networks via the access point forming the given network (S220; S340), the method further comprising: checking a received signal strength indication, RSSI, of the access point to which the electronic device is connected; and canceling the setting of the shared contents as the contents to be shared, when the RSSI is less than or equal to a predetermined value. storing, in the electronic device, a list of contents to be shared between the electronic device and another device (S200; S300), such that the contents to be shared are shared via at least one of a plurality of networks, each network comprising an access point, the electronic device and the other device, such that the electronic device and the other device are connected to the access point in order to be connected to one another, wherein the list of contents to be shared matches the access point, such that the list of contents to be shared is determined based on the access point; and setting, in the electronic device, contents included in the list of contents to be shared as shared contents in response to the electronic device being connected (S210; S320) to a given network of the plurality of networks via the access point forming the given network (S220; S340), the method further comprising: checking a received signal strength indication, RSSI, of the access point to which the electronic device is connected; and canceling the setting of the shared contents as the contents to be shared, when the RSSI is less than or equal to a predetermined value. checking a received signal strength indication, RSSI, of the access point to which the electronic device is connected; and canceling the setting of the shared contents as the contents to be shared, when the RSSI is less than or equal to a predetermined value.
An edge emitting laser light source comprising: a substrate; an active layer disposed on the substrate; a wavelength selection section comprising grating regions configured to select wavelengths of light emitted from the active layer; and a gain section configured to resonate the light having the selected wavelengths in a direction parallel with the active layer; wherein the grating regions are arranged in parallel with a light emitting direction from the gain section; and characterized in that the grating regions comprise a dielectric material comprising at least one of SiO 2, SiNx, TiO 2, MgF 2, Al 2 O 3 and Ta 2 0 5. a substrate; an active layer disposed on the substrate; a wavelength selection section comprising grating regions configured to select wavelengths of light emitted from the active layer; and a gain section configured to resonate the light having the selected wavelengths in a direction parallel with the active layer; wherein the grating regions are arranged in parallel with a light emitting direction from the gain section; and characterized in that the grating regions comprise a dielectric material comprising at least one of SiO 2, SiNx, TiO 2, MgF 2, Al 2 O 3 and Ta 2 0 5.
A bone plate for use with a bone having a periprosthetic fracture, the bone plate having a longitudinal axis that extends from a first end to a second end of the bone plate, the bone plate comprising: a planar bottom surface configured to face the bone; a top surface opposite the bottom surface; a plurality of side walls (108, 110) joining the top and bottom surfaces (112, 114); a plurality of outer apertures (132, 134) that extend through the bone plate from the top surface to the bottom surface, the plurality of outer apertures (132, 134) offset from the longitudinal axis in a direction perpendicular to the longitudinal axis; and a plurality of indentations in the side walls (108, 110), each indentation extending longitudinally between adjacent outer apertures (132, 134) to narrow the bone plate in a direction perpendicular to the longitudinal axis of the bone plate, characterized in that the bone plate comprises a plurality of central apertures that extend through the bone plate from the top surface to the bottom surface, the plurality of central apertures located along the longitudinal axis of the bone plate, wherein each of the plurality of the central apertures is positioned between two of the plurality of outer apertures (132, 134) forming a subset of apertures that extends diagonally across the bone plate. a planar bottom surface configured to face the bone; a top surface opposite the bottom surface; a plurality of side walls (108, 110) joining the top and bottom surfaces (112, 114); a plurality of outer apertures (132, 134) that extend through the bone plate from the top surface to the bottom surface, the plurality of outer apertures (132, 134) offset from the longitudinal axis in a direction perpendicular to the longitudinal axis; and a plurality of indentations in the side walls (108, 110), each indentation extending longitudinally between adjacent outer apertures (132, 134) to narrow the bone plate in a direction perpendicular to the longitudinal axis of the bone plate,
An integrated hydrogen fueling station for fueling of vehicle tanks with hydrogen comprising an electrochemical compressing unit in which secondary hydrogen originating from leakage, boiling-off or venting of hydrogen-containing gas in one or more of the fueling station operative units is compressed, wherein the secondary hydrogen contains hydrogen and further gaseous components, characterized by comprising one or more mechanical hydrogen compressing units producing secondary hydrogen which is collected and transferred to the electrochemical compressing unit.
A system for transferring decorations to substrates, comprising: a continuous web including a plurality of decorations (18, 1604) provided on a first side of the web, each decoration having a pressure sensitive adhesive exposed on a surface of the decoration facing outwardly from the first side of the web; an application station at which the decorations are transferred from the web to substrates; a web path along which the web travels to transport the decorations to the application station; a substrate transport (12, 14, 16) configured to move the substrates to the application station; a web control system including at least one web controller (118, 120, 500) configured to move the web at the application station to position a decoration on the web for transfer to a substrate; wherein the application station is configured to transfer a decoration from the web directly to a substrate based on contact of the substrate with the pressure sensitive adhesive of a portion of the decoration while the portion of the decoration is attached to the web, characterized in that the system further comprises an actuator (700, 800, 900) arranged to move the web and the substrate toward each other to apply an enhanced application force during transfer of the decoration to the substrate.
A method for determining strain on a turbine component: providing the turbine component comprising a plurality of strain sensor reference features disposed along the turbine component separated from one another by a plurality of first distances at a first time; traversing a traversable strain sensor reader along at least a portion of the turbine component at a second time to read the plurality of strain sensor reference features separated from one another by a plurality of second distances at the second time; and, comparing the plurality of second distances to the plurality of first distances to determine a plurality of non-linear strain measurements between the plurality of strain sensor reference features. providing the turbine component comprising a plurality of strain sensor reference features disposed along the turbine component separated from one another by a plurality of first distances at a first time; traversing a traversable strain sensor reader along at least a portion of the turbine component at a second time to read the plurality of strain sensor reference features separated from one another by a plurality of second distances at the second time; and, comparing the plurality of second distances to the plurality of first distances to determine a plurality of non-linear strain measurements between the plurality of strain sensor reference features.
One or more non-transitory computer-readable media having instructions executable by a processor (104, 704), the instructions programmed to perform a method comprising: defining a plurality of spatial regions distributed across a three-dimensional geometric surface corresponding to a patient's heart; detecting at least one wave front that propagates across the geometric surface based on electrical data representing electrophysiological signals for each of a plurality of nodes distributed on the geometric surface over at least one time interval; determining an indication of conduction velocity of the wave front for at least one spatial region of the plurality of spatial regions during the time interval based on a duration that the wave front resides within the at least one spatial region; identifying slow conduction activity for the at least one spatial region based on comparing the indication of conduction velocity relative to a threshold; and storing in memory (102, 702) conduction data representing the slow conduction activity identified for each spatial region. defining a plurality of spatial regions distributed across a three-dimensional geometric surface corresponding to a patient's heart; detecting at least one wave front that propagates across the geometric surface based on electrical data representing electrophysiological signals for each of a plurality of nodes distributed on the geometric surface over at least one time interval; determining an indication of conduction velocity of the wave front for at least one spatial region of the plurality of spatial regions during the time interval based on a duration that the wave front resides within the at least one spatial region; identifying slow conduction activity for the at least one spatial region based on comparing the indication of conduction velocity relative to a threshold; and storing in memory (102, 702) conduction data representing the slow conduction activity identified for each spatial region.
A chimeric peptide comprising a cytokine peptide and a ligand peptide, wherein the cytokine peptide is not a binding partner of the ligand peptide and wherein the ligand peptide is a binding partner to a receptor expressed on natural killer cells or CD8+ cytotoxic T lymphocytes (CTLs), wherein the receptor is the NKG2D receptor, and wherein the cytokine peptide is selected from the group consisting of IL2, IL7, IL15, IL18, IL21, and mutants thereof.
A sugar phosphate isomerase/epimerase variant consisting of an amino acid sequence represented by SEQ ID NO: 1, wherein alanine, which is an amino acid corresponding to position 321 of SEQ ID NO: 3, is substituted with valine.
A method for transforming multi-touch input into one or more manipulation events, the method performed in a computing device having multi-touch hardware, the method comprising: receiving from the multi-touch hardware low-level touch input that corresponds to touches on the multi-touch hardware; identifying an application object to which the received low-level touch input applies; sending the received low-level touch input and information about the identified application object to a manipulation Application Programming Interface, API, for interpreting the received low-level touch input as one or more manipulation events, wherein the manipulation API is invocable by multiple applications and provides an application-independent platform for processing multi-touch input; receiving a manipulation event that describes one or more manipulations of the identified application object, the manipulation event comprising a 2D affine transform of the identified application object; and handling the received manipulation event by modifying the identified application object, such that the application receives one or more manipulation events without performing steps specific to a particular multi-touch hardware device and without interpreting individual low-level touch inputs. receiving from the multi-touch hardware low-level touch input that corresponds to touches on the multi-touch hardware; identifying an application object to which the received low-level touch input applies; sending the received low-level touch input and information about the identified application object to a manipulation Application Programming Interface, API, for interpreting the received low-level touch input as one or more manipulation events, wherein the manipulation API is invocable by multiple applications and provides an application-independent platform for processing multi-touch input; receiving a manipulation event that describes one or more manipulations of the identified application object, the manipulation event comprising a 2D affine transform of the identified application object; and handling the received manipulation event by modifying the identified application object, such that the application receives one or more manipulation events without performing steps specific to a particular multi-touch hardware device and without interpreting individual low-level touch inputs.
A method performed by a base station in a wireless communication system, the method comprising: receiving, from a machine type communication, MTC, terminal (110, 111), an attach request message associated with a specific mobility management entity, MME, (130, 131); upon the reception of the attach request message, selecting, by a network node selection function, NNSF, of the base station, the MME (130, 131) for the attach request message among a plurality of MMEs connected with the base station by identifying the specific MME (130, 131) based on the attach request message associated with the specific MME (130, 131) transmitted by the MTC terminal (110, 111); and transmitting, to the selected MME (130, 131) supporting an MTC function, the attach request message and international mobile subscriber identity, IMSI, of the MTC terminal, wherein subscription information of the MTC terminal is obtained by the selected MME from a home subscriber server, HSS, and is used for the MTC terminal associated with the MTC function. receiving, from a machine type communication, MTC, terminal (110, 111), an attach request message associated with a specific mobility management entity, MME, (130, 131); upon the reception of the attach request message, selecting, by a network node selection function, NNSF, of the base station, the MME (130, 131) for the attach request message among a plurality of MMEs connected with the base station by identifying the specific MME (130, 131) based on the attach request message associated with the specific MME (130, 131) transmitted by the MTC terminal (110, 111); and transmitting, to the selected MME (130, 131) supporting an MTC function, the attach request message and international mobile subscriber identity, IMSI, of the MTC terminal, wherein subscription information of the MTC terminal is obtained by the selected MME from a home subscriber server, HSS, and is used for the MTC terminal associated with the MTC function.
An aircraft comprising: a primary aircraft structure, a cabin structure segment, a force transmitting element, wherein the primary aircraft structure comprises frames and stringers that are designed for absorbing a force (Q', L) in one direction only, wherein the force transmitting element separably connects the cabin structure segment to the primary aircraft structure, and wherein the force transmitting element comprises a cabin bearing element, as well as a structure bearing element, wherein the cabin bearing element is connected to the cabin structure segment and the structure bearing element is connected to the primary aircraft structure, wherein the force transmitting element is designed in such a way that a force transmission between the cabin structure segment and the primary aircraft structure can take place with at least one degree of freedom of motion, and wherein the force transmitting element is arranged on a frame or a stringer such that only forces are introduced into the stringer that occur along the aircraft longitudinal axis, respectively only forces (Q') are introduced into the frame that act perpendicular on the frame. a primary aircraft structure, a cabin structure segment, a force transmitting element, wherein the primary aircraft structure comprises frames and stringers that are designed for absorbing a force (Q', L) in one direction only, wherein the force transmitting element separably connects the cabin structure segment to the primary aircraft structure, and wherein the force transmitting element comprises a cabin bearing element, as well as a structure bearing element,