mhurhangee/ep-ind-claims huggingface dataset:
An antigen-binding protein, wherein the antigen-binding protein is capable of binding to a single epitope, which epitope is comprised in the CH1 domain of each of human IgG1, human IgG2, human IgG3 and human IgG4, wherein the antigen-binding protein is cross-blocked by a VHH having the amino acid sequence of SEQ ID NO: 1, and wherein the antigen-binding protein is selected from: A) an antibody obtainable from camelids or sharks, which antibody consists of only heavy chains and is naturally devoid of light chains; B) a variable domain of an antibody defined in A); or, C) a variable domain wherein the frame work sequences of a variable domain defined in B) are grafted with CDRs obtained from other sources. A) an antibody obtainable from camelids or sharks, which antibody consists of only heavy chains and is naturally devoid of light chains; B) a variable domain of an antibody defined in A); or, C) a variable domain wherein the frame work sequences of a variable domain defined in B) are grafted with CDRs obtained from other sources.
An Exhaust Aftertreatment System (EATS) comprising a housing, a pre-SCR (Selective Catalytic Reduction) insert, a PF (Particulate Filter) insert, a first main SCR insert and an exhaust pipe, the pre-SCR insert being arranged to receive exhaust gas entering the EATS, the PF insert being arranged downstream the pre-SCR insert and the first main SCR insert being arranged downstream the PF insert, characterized in that the pre-SCR insert, the PF insert and the first main SCR insert are arranged in the housing and are each removably mounted in the housing such that each insert (3,4,5,6) may be removed separately from the housing, the pre-SCR insert being mounted along a first geometric axis, the PF insert being mounted along a second geometric axis and the first main SCR insert is mounted along a third geometric axis, the first geometric axis being parallel with the second geometric axis and the third geometric axis is parallel with the first and the second geometric axes (a1,a2) or alternatively coincides with either one of the first and the second geometric axis (a1,a2) and is parallel with the other one of the first and the second geometric axis (a1,a2).
A device comprising: a processor coupled to a memory, a display including a touch screen for detecting touch events at the display, an orientation sensor, and a proximity sensor, the processor: when (a) an initial proximity event occurs at the proximity sensor, and/or (b) a reorientation event occurs at the orientation sensor: buffers in the memory touch data received via the touch screen; and, thereafter: processes the buffered touch data when a proximity event does not occur within a given time period; and, disables the touch screen and discards the buffered touch data when a proximity event occurs within the given time period, wherein when the processor determines that an initial proximity event has occurred at the proximity sensor and no reorientation event has occurred at the orientation sensor, the given time period is less than when the processor determines that a reorientation event has occurred at the orientation sensor. when (a) an initial proximity event occurs at the proximity sensor, and/or (b) a reorientation event occurs at the orientation sensor: buffers in the memory touch data received via the touch screen; and, thereafter: processes the buffered touch data when a proximity event does not occur within a given time period; and, disables the touch screen and discards the buffered touch data when a proximity event occurs within the given time period, processes the buffered touch data when a proximity event does not occur within a given time period; and, disables the touch screen and discards the buffered touch data when a proximity event occurs within the given time period, wherein when the processor determines that an initial proximity event has occurred at the proximity sensor and no reorientation event has occurred at the orientation sensor, the given time period is less than when the processor determines that a reorientation event has occurred at the orientation sensor.
Body-wearable element, comprising at least one piezoelectric element that is designed to vibrate and to thereby produce a haptic impression for an audible signal, characterized in that the body-wearable element is arranged and designed to apply to the piezoelectric element a haptically perceptible signal that has been determined from the audible signal by multiplying the frequencies of the audible signal by a scaling factor and thereby converting the audible signal into the haptically perceptible signal, the scaling factor being less than 1 because the haptically perceptible frequencies are lower than the frequencies of the audibly perceptible frequency spectrum. comprising at least one piezoelectric element that is designed to vibrate and to thereby produce a haptic impression for an audible signal, characterized in that the body-wearable element is arranged and designed to apply to the piezoelectric element a haptically perceptible signal that has been determined from the audible signal by multiplying the frequencies of the audible signal by a scaling factor and thereby converting the audible signal into the haptically perceptible signal, the scaling factor being less than 1 because the haptically perceptible frequencies are lower than the frequencies of the audibly perceptible frequency spectrum.
The use of a single lubricating oil composition to lubricate both the cylinder liner and the crankcase of a marine diesel crosshead engine; the single lubricating oil composition comprising: - at least 60 mass% of a mineral oil having a kinematic viscosity at 100°C of from 2 to 40 mm 2 s -1 and a viscosity index of from 80 to 100; - 0.5 to 30 mass% of at least one complex/hybrid detergent including phenol, sulphonic acid and salicylic acid surfactants; - 0.5 to 6.0 mass% of at least one ashless succinimide dispersant; - 0.1 to 1.5 mass% of at least one zinc dihydrocarbyl dithiophosphate anti-wear additive; and - a phenate detergent the single lubricating oil composition having a TBN, as measured using ASTM D 2896-98, of 10 to 55 mg KOH/g, and a kinematic viscosity at 100°C of 15 to 21 cSt, wherein the single lubricating oil composition provides the crankcase of the engine with rust and deposit control, and controls deposits, corrosive wear and high temperature resistance in the cylinder. - at least 60 mass% of a mineral oil having a kinematic viscosity at 100°C of from 2 to 40 mm 2 s -1 and a viscosity index of from 80 to 100; - 0.5 to 30 mass% of at least one complex/hybrid detergent including phenol, sulphonic acid and salicylic acid surfactants; - 0.5 to 6.0 mass% of at least one ashless succinimide dispersant; - 0.1 to 1.5 mass% of at least one zinc dihydrocarbyl dithiophosphate anti-wear additive; and - a phenate detergent
A magnetic insertion meter (200; 300; 400) comprising: a sensor head tube (240; 340; 440) having a textured front surface; and at least two electrodes (210; 310; 410, 411, 412), characterised in that the textured front surface is at least one of an abrasive on a substrate, an impregnated abrasive, a deposited abrasive, and/or an abrasive layer. a sensor head tube (240; 340; 440) having a textured front surface; and at least two electrodes (210; 310; 410, 411, 412), characterised in that the textured front surface is at least one of an abrasive on a substrate, an impregnated abrasive, a deposited abrasive, and/or an abrasive layer.
A radio frequency identification (RFID) device, comprising: a receive antenna; a transmit antenna; a multiresonator comprising a plurality of resonators (104A - 104D), wherein the multiresonator is electrically coupled between the receive antenna and the transmit antenna; and a sensor material bridging two or more electrically conductive structures of the RFID device, wherein the sensor material has a variable electrical conductivity that is configured to change depending on an environmental condition to which the sensor material is exposed, the RFID further comprising: a first arm of the multiresonator; and a second arm of the multiresonator spaced from the first arm by an interstitial space, wherein the sensor material is positioned within the interstitial space and bridges a width of the interstitial space between the first arm and the second arm, such that a resonation amplitude of the multiresonator is attenuated by an amount dependent on the electrical conductivity of the sensor material. a receive antenna; a transmit antenna; a multiresonator comprising a plurality of resonators (104A - 104D), wherein the multiresonator is electrically coupled between the receive antenna and the transmit antenna; and a sensor material bridging two or more electrically conductive structures of the RFID device, wherein the sensor material has a variable electrical conductivity that is configured to change depending on an environmental condition to which the sensor material is exposed, the RFID further comprising: a first arm of the multiresonator; and a second arm of the multiresonator spaced from the first arm by an interstitial space, wherein the sensor material is positioned within the interstitial space and bridges a width of the interstitial space between the first arm and the second arm, such that a resonation amplitude of the multiresonator is attenuated by an amount dependent on the electrical conductivity of the sensor material. a first arm of the multiresonator; and a second arm of the multiresonator spaced from the first arm by an interstitial space, wherein the sensor material is positioned within the interstitial space and bridges a width of the interstitial space between the first arm and the second arm, such that a resonation amplitude of the multiresonator is attenuated by an amount dependent on the electrical conductivity of the sensor material.
A system for load-balancing a web server farm on cloud computing infrastructure, the system comprising: an application executing on a plurality of cloud infrastructure components, the plurality of cloud infrastructure components comprising: a static host configured to host static content corresponding to the application; a plurality of virtual web servers (301a, 301b, 301c) comprising cloud computing components and communicatively coupled to the static host and configured to host dynamic content corresponding to the application; and an application engine on a cloud computing resource and communicatively coupled to the plurality of virtual web servers (301a, 301b, 301c) and configured to collect load information corresponding to the plurality of virtual web servers (301a, 301b, 301c), wherein the collected load information is hosted at the static host and is periodically updated by the application engine; wherein upon establishing an initial contact from a client browser at the static host, static content corresponding to the application is loaded on the client browser; and wherein, based on the load information, the client browser selects an available virtual web server from the plurality of virtual web servers (301a, 301b, 301c) to access the dynamic content corresponding to the application. an application executing on a plurality of cloud infrastructure components, the plurality of cloud infrastructure components comprising: a static host configured to host static content corresponding to the application; a plurality of virtual web servers (301a, 301b, 301c) comprising cloud computing components and communicatively coupled to the static host and configured to host dynamic content corresponding to the application; and an application engine on a cloud computing resource and communicatively coupled to the plurality of virtual web servers (301a, 301b, 301c) and configured to collect load information corresponding to the plurality of virtual web servers (301a, 301b, 301c), a static host configured to host static content corresponding to the application; a plurality of virtual web servers (301a, 301b, 301c) comprising cloud computing components and communicatively coupled to the static host and configured to host dynamic content corresponding to the application; and an application engine on a cloud computing resource and communicatively coupled to the plurality of virtual web servers (301a, 301b, 301c) and configured to collect load information corresponding to the plurality of virtual web servers (301a, 301b, 301c), wherein the collected load information is hosted at the static host and is periodically updated by the application engine; wherein upon establishing an initial contact from a client browser at the static host, static content corresponding to the application is loaded on the client browser; and wherein, based on the load information, the client browser selects an available virtual web server from the plurality of virtual web servers (301a, 301b, 301c) to access the dynamic content corresponding to the application.
A gamma-retroviral recombinant expression vector comprising a nucleic acid comprising a nucleotide sequence encoding a chimeric antigen receptor, wherein the CAR comprises: an antigen binding domain of HN1, a transmembrane domain, and an intracellular T cell signaling domain, wherein the HN1 comprises a light chain variable region comprising SEQ ID NO: 3 and a heavy chain variable region comprising SEQ ID NO: 6, optionally wherein: (a) the transmembrane domain comprises i) CD8 and/or ii) CD28; (b) the intracellular T cell signaling domain comprises i) CD28, ii) CD137, and/or iii) CD3 zeta; (c) the intracellular T cell signaling domain comprises a CD28 amino acid sequence comprising SEQ ID NO: 15; (d) the intracellular T cell signaling domain comprises a CD137 amino acid sequence comprising SEQ ID NO: 16; and/or (e) the intracellular T cell signaling domain comprises a CD3 zeta amino acid sequence comprising SEQ ID NO: 17. (a) the transmembrane domain comprises i) CD8 and/or ii) CD28; (b) the intracellular T cell signaling domain comprises i) CD28, ii) CD137, and/or iii) CD3 zeta; (c) the intracellular T cell signaling domain comprises a CD28 amino acid sequence comprising SEQ ID NO: 15; (d) the intracellular T cell signaling domain comprises a CD137 amino acid sequence comprising SEQ ID NO: 16; and/or (e) the intracellular T cell signaling domain comprises a CD3 zeta amino acid sequence comprising SEQ ID NO: 17.
Use of an α-lactalbumin enriched whey protein extract as a source of cholesterol in a synthetic nutritional composition for an infant or child, wherein the α-lactalbumin enriched WPE is obtained by a process comprising: a. acidifying a whey protein product to pH 4 or below b. forming a low calcium whey protein product by concentrating the proteins in the acidified whey protein until the calcium to protein ratio is less than about 0.001 and, c. precipitating α-lactalbumin from the low-calcium whey protein product, wherein said precipitating step includes the sub-steps of: diluting the low-calcium whey protein product, adjusting the pH of the diluted low-calcium whey protein product to between 4 and 5 to form a precipitate and soluble proteins, and Separating the precipitate proteins from the soluble proteins; Wherein the WPE is added to said composition in an effective amount sufficient to ensure that said synthetic nutritional composition has a final concentration of cholesterol found in human breast milk. a. acidifying a whey protein product to pH 4 or below b. forming a low calcium whey protein product by concentrating the proteins in the acidified whey protein until the calcium to protein ratio is less than about 0.001 and, c. precipitating α-lactalbumin from the low-calcium whey protein product, wherein said precipitating step includes the sub-steps of: diluting the low-calcium whey protein product, adjusting the pH of the diluted low-calcium whey protein product to between 4 and 5 to form a precipitate and soluble proteins, and Separating the precipitate proteins from the soluble proteins; diluting the low-calcium whey protein product, adjusting the pH of the diluted low-calcium whey protein product to between 4 and 5 to form a precipitate and soluble proteins, and Separating the precipitate proteins from the soluble proteins;
A method for wireless communications by a user equipment, UE, comprising: deciding that a starting subframe for a random access response, RAR, transmission or a single cell point to multipoint, SC-PTM, transmission will occur or has occurred; determining occurrence of a narrowband reference signal, NRS, in a non-anchor resource block, RB, based on one or more narrowband transmission parameters, wherein the narrowband transmission parameters comprise a length of a longest narrowband physical downlink control channel, NPDCCH, candidate and a minimum number of subframes, N, for transmission of NRSs after the end of the longest NPDCCH candidate; and processing the NRS in at least the length plus N subframes after the RAR transmission, or the SC-PTM transmission. deciding that a starting subframe for a random access response, RAR, transmission or a single cell point to multipoint, SC-PTM, transmission will occur or has occurred; determining occurrence of a narrowband reference signal, NRS, in a non-anchor resource block, RB, based on one or more narrowband transmission parameters, wherein the narrowband transmission parameters comprise a length of a longest narrowband physical downlink control channel, NPDCCH, candidate and a minimum number of subframes, N, for transmission of NRSs after the end of the longest NPDCCH candidate; and processing the NRS in at least the length plus N subframes after the RAR transmission, or the SC-PTM transmission.
A method of manufacture of an amorphous copolyester, comprising polymerizing, in the presence of an esterification catalyst (a) a monomer of formula I wherein R 1, R 2, R 3, and R 5 are each independently a C 1-3 alkyl group, a is 0-1, b is 0-4, c is 0-4, and d is 0-3, and each R 4 is independently hydrogen or a C 1-3 alkyl group; (b) more than 38 to 43 mol % based on the total moles of repeat units of the polymer, of a virgin monomer selected from a di(C 1-3 alkyl) terephthalate, and combinations thereof, and (c) 50 mol % based on the total moles of repeat units of the polymer, of 1,4-cyclohexane dimethanol; wherein the residue of monomer (a) is present in an amount from 7 to less than 12 mole % of the copolyester based on moles of repeat units in the polyester; and wherein the copolyester has a glass transition temperature of at least 107°C as determined according to ASTM D3418, an intrinsic viscosity of at least 0.7 dl/g as determined by a viscometer in which the polymer sample was dissolved in a 60/40 mixture by volume% of phenol/1,1,2,2-tetrachloroethane solution, and a molded sample has a Notched Izod value of at least 290 J/m determined in accordance with ASTM D256. (a) a monomer of formula I wherein R 1, R 2, R 3, and R 5 are each independently a C 1-3 alkyl group, a is 0-1, b is 0-4, c is 0-4, and d is 0-3, and each R 4 is independently hydrogen or a C 1-3 alkyl group; R 1, R 2, R 3, and R 5 are each independently a C 1-3 alkyl group, a is 0-1, b is 0-4, c is 0-4, and d is 0-3, and each R 4 is independently hydrogen or a C 1-3 alkyl group; (b) more than 38 to 43 mol % based on the total moles of repeat units of the polymer, of a virgin monomer selected from a di(C 1-3 alkyl) terephthalate, and combinations thereof, and (c) 50 mol % based on the total moles of repeat units of the polymer, of 1,4-cyclohexane dimethanol; the residue of monomer (a) is present in an amount from 7 to less than 12 mole % of the copolyester based on moles of repeat units in the polyester; and wherein the copolyester has a glass transition temperature of at least 107°C as determined according to ASTM D3418, an intrinsic viscosity of at least 0.7 dl/g as determined by a viscometer in which the polymer sample was dissolved in a 60/40 mixture by volume% of phenol/1,1,2,2-tetrachloroethane solution, and a glass transition temperature of at least 107°C as determined according to ASTM D3418, an intrinsic viscosity of at least 0.7 dl/g as determined by a viscometer in which the polymer sample was dissolved in a 60/40 mixture by volume% of phenol/1,1,2,2-tetrachloroethane solution, and a molded sample has a Notched Izod value of at least 290 J/m determined in accordance with ASTM D256.
A coupler telescopic apparatus, comprising a housing and a drawbar capable of extending and retracting along the housing, the housing being sleeved outside the drawbar; the coupler telescopic apparatus being characterized in that a limiting block is fixedly arranged on an outer side face of the drawbar, a locking ring capable of coming into contact with the limiting block is sleeved inside the housing, and the locking ring is coaxial with the housing and rotatably connected to the housing; a through groove is axially formed on an inner surface of the locking ring, and the through groove corresponds to the limiting block in shape, so that the limiting block passes through the through groove when the through groove is aligned with the limiting block, and then an extension of the drawbar is locked by rotating the locking ring to block the limiting block after the extension of the drawbar is completed; a telescopic cylinder is arranged in the housing, and two ends of the telescopic cylinder are connected to the housing and the drawbar, respectively, to drive the drawbar to extend or retract along the housing.
A method for producing a reinforcement element consisting of fiber-reinforced plastic for mineral construction materials, particularly for concrete, with said method comprising the following steps: - impregnating a plurality of fibers with plastic, - pre-curing the fibers enclosed with plastic into a composite fiber rod in a first curing stage by supplying heat and/or radiation, - cutting the composite fiber rod, if necessary, to the length desired for the reinforcement elements, - forming the pre-cured composite fiber rod into a shape desired for the reinforcement element, and - curing the composite fiber rod in a final curing stage by supplying heat and/or radiation, characterized in that the curing of the composite fiber rod takes place in at least three successive curing stages (7, 16, 25), in that at least one radiation-reflecting and/or heat-insulating covering means is after the first curing stage applied on the pre-cured composite fiber rod over at least one individual section of the composite fiber rod and covers the composite fiber rod over at least part of its circumference in this at least one section, wherein a second curing stage of the composite fiber rod is carried out together with the one or more sectionally applied covering means, and wherein the composite fiber rod additionally cures in the sections, which are not covered with a covering means, in said second curing stage due to the supply of radiation and/or heat, and in that the deformation of the composite fiber rod is carried out between the second curing stage and the final curing stage. - impregnating a plurality of fibers with plastic, - pre-curing the fibers enclosed with plastic into a composite fiber rod in a first curing stage by supplying heat and/or radiation, - cutting the composite fiber rod, if necessary, to the length desired for the reinforcement elements, - forming the pre-cured composite fiber rod into a shape desired for the reinforcement element, and - curing the composite fiber rod in a final curing stage by supplying heat and/or radiation,
A composition for use in treating tooth sensitivity in an individual, wherein: the composition comprises a Wnt3A protein inserted in the non-aqueous phase of a lipid structure, whereby the composition is administered to exposed dentin of a tooth and the Wnt3A protein penetrates the exposed dentin through dentinal tubules to an underlying pulp tissue, and wherein the underlying pulp tissue of the tooth is not exposed.