mhurhangee/ep-ind-claims huggingface dataset:
A cyclohexenone compound of the following formula: wherein each of X and Y independently is oxygen, NR 5 or sulfur; R is a hydrogen or C(=O)C 1 -C 8 alkyl; each of R 1, R 2 and R 3 independently is a hydrogen, methyl or (CH 2) m -CH 3; R 4 is NR 5 R 6, OR 5, OC(=O)R 7, C(=O)OR 5, C(=O)R 5, C(=O)NR 5 R 6, halogen, 5 or 6-membered lactone, C 1 -C 8 alkyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, aryl, glucosyl, wherein the 5 or 6-membered lactone, C 1 -C 8 alkyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, aryl, and glucosyl are optionally substituted with one or more substituents selected from NR 5 R 6, OR 5, OC(=O)R 7, C(=O)OR 5, C(=O)R 5, C(=O)NR 5 R 6, C 1 -C 8 alkyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, C 3 -C 8 cycloalkyl, and C 1 -C 8 haloalkyl; each of R 5 and R 6 is independently a hydrogen or C 1 -C 8 alkyl; R 7 is a C 1 -C 8 alkyl, OR 5 or NR 5 R 6; m = 1-12; and n=1-12; or a pharmaceutically acceptable salt, or solvate thereof, for its use in treating, inhibiting and/or preventing fatty liver disease. wherein each of X and Y independently is oxygen, NR 5 or sulfur; R is a hydrogen or C(=O)C 1 -C 8 alkyl; each of R 1, R 2 and R 3 independently is a hydrogen, methyl or (CH 2) m -CH 3; R 4 is NR 5 R 6, OR 5, OC(=O)R 7, C(=O)OR 5, C(=O)R 5, C(=O)NR 5 R 6, halogen, 5 or 6-membered lactone, C 1 -C 8 alkyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, aryl, glucosyl, wherein the 5 or 6-membered lactone, C 1 -C 8 alkyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, aryl, and glucosyl are optionally substituted with one or more substituents selected from NR 5 R 6, OR 5, OC(=O)R 7, C(=O)OR 5, C(=O)R 5, C(=O)NR 5 R 6, C 1 -C 8 alkyl, C 2 -C 8 alkenyl, C 2 -C 8 alkynyl, C 3 -C 8 cycloalkyl, and C 1 -C 8 haloalkyl; each of R 5 and R 6 is independently a hydrogen or C 1 -C 8 alkyl; R 7 is a C 1 -C 8 alkyl, OR 5 or NR 5 R 6; m = 1-12; and n=1-12; or a pharmaceutically acceptable salt, or solvate thereof, for its use in treating, inhibiting and/or preventing fatty liver disease.
A medical device, comprising: implantable electrodes including at least a first electrode configured to be disposed for pacing at a first site of a heart chamber and a second electrode configured to be disposed for pacing at a second site of the heart chamber; pacing circuitry configured to deliver, during a cardiac cycle: a first pacing pulse to the first site using the first electrode as a cathode electrode for the first pacing pulse, and a second pacing pulse to the second site using the second electrode as a cathode electrode for the second pacing pulse; sensing circuitry configured to sense a cardiac response to the pacing pulses including sensing cardiac electrical activity using the implantable electrodes, the sensing circuitry further configured to generate a differential signal between sensed cardiac electrical activity at the first electrode and sensed cardiac electrical activity at the second electrode; and capture circuitry configured to discriminate between single site capture of pulses delivered to multiple sites within a single heart chamber during a cardiac cycle, comprising capture by one of the first pacing pulse or the second pacing pulse, and multi-site capture of pulses delivered to multiple sites within a single heart chamber during a cardiac cycle, comprising capture by both the first pacing pulse and the second pacing pulse, based on the differential signal. implantable electrodes including at least a first electrode configured to be disposed for pacing at a first site of a heart chamber and a second electrode configured to be disposed for pacing at a second site of the heart chamber; pacing circuitry configured to deliver, during a cardiac cycle: a first pacing pulse to the first site using the first electrode as a cathode electrode for the first pacing pulse, and a second pacing pulse to the second site using the second electrode as a cathode electrode for the second pacing pulse; a first pacing pulse to the first site using the first electrode as a cathode electrode for the first pacing pulse, and a second pacing pulse to the second site using the second electrode as a cathode electrode for the second pacing pulse; sensing circuitry configured to sense a cardiac response to the pacing pulses including sensing cardiac electrical activity using the implantable electrodes, the sensing circuitry further configured to generate a differential signal between sensed cardiac electrical activity at the first electrode and sensed cardiac electrical activity at the second electrode; and capture circuitry configured to discriminate between single site capture of pulses delivered to multiple sites within a single heart chamber during a cardiac cycle, comprising capture by one of the first pacing pulse or the second pacing pulse, and multi-site capture of pulses delivered to multiple sites within a single heart chamber during a cardiac cycle, comprising capture by both the first pacing pulse and the second pacing pulse, based on the differential signal.
Bearing comprising a bearing ring supporting a plurality of rolling elements, the bearing ring comprising an outer surface and a groove around a circumference of the outer surface accommodating a fibre sensor, the bearing further comprising a clamping element, engaging the fibre sensor with a clamping force acting in a radial direction of the bearing ring such that the fibre sensor intimately engages the bearing ring.
A drug delivery device comprising; a housing; a cylindrical member configured to be rotatably supported inside the housing, characterized in that the outer surface of the cylindrical member is provided with a single helical track comprising a sequence of encoded images, wherein each encoded image comprises a matrix of points within a grid or a bar code; and an optical sensor directed at the helical track of the cylindrical member and configured to detect features of the encoded images.
A co-culture method of adipocytes and macrophages, comprising: (a) preparing a mixture including preadipocytes, macrophages and alginate hydrogels, which further include one or more selected from the group consisting of collagen, chitosan, hyaluronic acid, and gelatin; (b) manufacturing hydrogel scaffolds including preadipocytes and macrophages from the mixture using a three-dimensional cell-printing system; (c) forming crosslinks using a calcium chloride in the hydrogel scaffolds; and (d) treating a culture fluid so that the preadipocytes and the macrophages included in the hydrogel scaffolds are proliferated and differentiated to form like adipose tissue. (a) preparing a mixture including preadipocytes, macrophages and alginate hydrogels, which further include one or more selected from the group consisting of collagen, chitosan, hyaluronic acid, and gelatin; (b) manufacturing hydrogel scaffolds including preadipocytes and macrophages from the mixture using a three-dimensional cell-printing system; (c) forming crosslinks using a calcium chloride in the hydrogel scaffolds; and (d) treating a culture fluid so that the preadipocytes and the macrophages included in the hydrogel scaffolds are proliferated and differentiated to form like adipose tissue.
An automatic swimming pool cleaner comprising: a. a body including a fluid inlet and a fluid outlet; b. a debris filter, at least a portion of which is positioned between the fluid inlet and the fluid outlet; and c. a pressure sensor assembly, comprising a differential pressure sensor assembly, configured to evidence accumulation of debris in the debris filter, characterised in that the differential pressure sensor assembly comprises: a. a magnet; and b. means, comprising a Hall effect sensor or a reed switch, configured to interact with the magnet. a. a body including a fluid inlet and a fluid outlet; b. a debris filter, at least a portion of which is positioned between the fluid inlet and the fluid outlet; and c. a pressure sensor assembly, comprising a differential pressure sensor assembly, configured to evidence accumulation of debris in the debris filter, a. a magnet; and b. means, comprising a Hall effect sensor or a reed switch, configured to interact with the magnet.
A microfluidic device for in-process monitoring of cell culture conditions including for example one or more of: cell density; cell viability; secreted proteins; protein analysis; epitope markers; concentrations of metabolites or nutrients and antigenic determinations; the device comprising: a cell inlet path; plural fluid reservoirs in fluid communication with the cell inlet path, a cell analysis area in fluid communication with said path and reservoirs, and a waste storage volume also in fluid communication with the cell analysis area, the device being operable to cause a primary fluid flow along the inlet path to the analysis area, and to selectively cause secondary fluid flow(s) into the inlet path from one or more of the selected reservoirs to combine with the primary fluid flow from the inlet path, in each case for analysis at the cell analysis area, the device being further operable to cause a fluid flow of the primary and any combined secondary flows from the cell analysis area into the waste storage volume, wherein, the cell analysis area includes multiple cell culture analysers for determining multiple said cell culture conditions.
A heated sensitive film sensor obtained by integrated circuit manufacturing technology, comprising: • an insulating substrate bearing a sensitive layer; • two complementary measuring electrodes (E1, E2) in the form of two adjacent conductive tracks arranged in electrical contact with the sensitive layer to measure the resistivity of the sensitive layer between the two conductive electrodes; • a heating element in the form of a resistive track arranged on the substrate to heat an active area of the sensitive layer, the resistive track comprising at least three power supply points (0, Vh') evenly spaced along a length of the resistive track, whereby the resistive track is divided into a plurality of segments between the power supply points; and • the resistive track has successive U-shaped arcs; characterised in that: • a first of the two electrode tracks penetrates at least one of the arcs of the resistive track and extends parallel to the arc, forming a second arc adjacent to the arc of the resistive track; and • the second of the two electrode tracks enters the second arc and is adjacent to the second arc. • an insulating substrate bearing a sensitive layer; • two complementary measuring electrodes (E1, E2) in the form of two adjacent conductive tracks arranged in electrical contact with the sensitive layer to measure the resistivity of the sensitive layer between the two conductive electrodes; • a heating element in the form of a resistive track arranged on the substrate to heat an active area of the sensitive layer, the resistive track comprising at least three power supply points (0, Vh') evenly spaced along a length of the resistive track, whereby the resistive track is divided into a plurality of segments between the power supply points; and • the resistive track has successive U-shaped arcs; • a first of the two electrode tracks penetrates at least one of the arcs of the resistive track and extends parallel to the arc, forming a second arc adjacent to the arc of the resistive track; and • the second of the two electrode tracks enters the second arc and is adjacent to the second arc.
An aircraft interior panel, comprising: a core panel sandwiched between structural plies, wherein the structural plies are sandwiched between doubler plies; a panel insert embedded within the aircraft interior panel and configured for receiving a fastener for attaching a load to the aircraft interior panel, the panel insert passing through and interrupting the core panel, wherein the panel insert includes an elongate stem; and facing sheets bonded outward of the panel insert for concealing the panel insert within the aircraft interior panel, wherein the elongated stem is capped on each end with an enlarged flange, the elongate stem being arranged axially perpendicular to the core panel and the enlarged flanges being arranged parallel to the core panel, the panel insert including male and female halves (30, 32) that press together to engage a locking feature preventing the two halves from being pulled apart, and the male and female halves (30, 32), when engaged, sandwiching the core panel, the structural plies and the doubler plies between the enlarged flanges. a core panel sandwiched between structural plies, wherein the structural plies are sandwiched between doubler plies; a panel insert embedded within the aircraft interior panel and configured for receiving a fastener for attaching a load to the aircraft interior panel, the panel insert passing through and interrupting the core panel, wherein the panel insert includes an elongate stem; and
A data retransmission request device for use in a multi-tone data transmission system wherein data are hierarchically modulated on a set of M tones for being transmitted between a transmitter and a receiver and wherein data are hierarchically modulated such that data bits that are most error sensitive are assigned to the lowest hierarchical level(s) and data bits that are less error sensitive are assigned to the higher hierarchical level(s), wherein said data retransmission request device is adapted to request to said transmitter retransmission of a data transmission unit that is hierarchically modulated at a particular hierarchical level and that is modulated on a particular group of N tones, N being a positive integer value greater than one and smaller than or equal to M.
Filter element for an extractor hood, which has filter material for absorbing odorous substances from an air flow that flows against the filter element, characterised in that the filter material consists of at least one mineral adsorber, which at least partially consists of a phyllosilicate, no further material is contained as filter material in the filter element other than the mineral adsorbers and the filter material is present in layers (121, 122, 123) in the filter element, wherein the composition of the filter material of at least two layers (121, 122, 123) is different from one another.
A particle heat exchanger comprising: a housing including: an inlet located at the top of the housing, and an outlet located below the inlet, the housing configured to enclose a flow of heat transfer particles which flows downwardly from the inlet to the outlet within the housing; at least one heat transfer tube including a heat transfer medium, each heat transfer tube being enclosed in the housing and in contact with the flow of heat transfer particles therein, each heat transfer tube extending substantially parallel to an axis extending between the inlet and outlet of the housing; and at least one divider located between the inlet and outlet of the housing, the at least one heat transfer tube extending through each divider, each divider including at least one opening configured to form at least one flow constriction in the flow of heat transfer particles between the inlet and outlet of the housing. a housing including: an inlet located at the top of the housing, and an outlet located below the inlet, the housing configured to enclose a flow of heat transfer particles which flows downwardly from the inlet to the outlet within the housing; an inlet located at the top of the housing, and an outlet located below the inlet, the housing configured to enclose a flow of heat transfer particles which flows downwardly from the inlet to the outlet within the housing; at least one heat transfer tube including a heat transfer medium, each heat transfer tube being enclosed in the housing and in contact with the flow of heat transfer particles therein, each heat transfer tube extending substantially parallel to an axis extending between the inlet and outlet of the housing; and at least one divider located between the inlet and outlet of the housing, the at least one heat transfer tube extending through each divider, each divider including at least one opening configured to form at least one flow constriction in the flow of heat transfer particles between the inlet and outlet of the housing.
Method of preparing potassium hydroxide dihydrate having a sodium content of less than 0.05 wt% based on the weight of the potassium hydroxide crystals comprising (a) providing a saturated potassium hydroxide solution having a temperature in the range from -25 to 33 °C. (b) cooling said solution in such a way that the variation in temperature is in a range from 0.001 to 5 °C/h to form crystals of potassium hydroxide dihydrate (c) separating potassium hydroxide dihydrate crystals from the solution. (a) providing a saturated potassium hydroxide solution having a temperature in the range from -25 to 33 °C. (b) cooling said solution in such a way that the variation in temperature is in a range from 0.001 to 5 °C/h to form crystals of potassium hydroxide dihydrate (c) separating potassium hydroxide dihydrate crystals from the solution.
A sustained release pheromone carrier comprising: a first sheet part and a second sheet part; at least one sex pheromone substance that is carried on at least a part of the first and second sheet parts (1, 2), characterized in that the first sheet part and the second sheet part are provided by bending a single polymer sheet so that the first and second sheet parts (1,2) are arranged face-to-face, the first and second sheet parts (1,2) each having an engaging hole (7,8) therethrough; a bend part is located between the first sheet part and the second sheet part and slits (4,5), each having a beginning end and a terminal end and extending therebetween, the beginning end being located at the bend part and the terminal end being located on each peripheral edge of the engaging holes (7,8) in the first and second sheet parts (1,2), at least one protrusion having one constriction, said protrusion inwardly extends from a part of a peripheral edge of each engaging hole (7,8) except a point on which the terminal end of each slit (4,5) is located, wherein the sustained release pheromone carrier can be secured to a rod-shaped support by guiding the rod-shaped support through the slits into the engaging holes and engaging the rod-shaped support with the engaging holes. a first sheet part and a second sheet part; at least one sex pheromone substance that is carried on at least a part of the first and second sheet parts (1, 2), characterized in that the first sheet part and the second sheet part are provided by bending a single polymer sheet so that the first and second sheet parts (1,2) are arranged face-to-face, the first and second sheet parts (1,2) each having an engaging hole (7,8) therethrough; a bend part is located between the first sheet part and the second sheet part and slits (4,5), each having a beginning end and a terminal end and extending therebetween, the beginning end being located at the bend part and the terminal end being located on each peripheral edge of the engaging holes (7,8) in the first and second sheet parts (1,2), at least one protrusion having one constriction, said protrusion inwardly extends from a part of a peripheral edge of each engaging hole (7,8) except a point on which the terminal end of each slit (4,5) is located,
A compound represented by the general formula or a pharmacologically acceptable salt thereof: wherein R represents an optionally substituted aryl group (the substituent(s) is 1 to 3 identical or different groups selected from the group consisting of a halogen atom, a C 1-6 alkyl group, a C 3-7 cycloalkyl group, a trifluoromethyl group, a difluoromethoxy group, a trifluoromethoxy group, a cyano group, a C 1-6 alkoxy group, a C 3-7 cycloalkoxy group, a phenyl group, a C 2-7 alkoxycarbonyl group, a benzyloxycarbonyl group, a di(C 1-6 alkyl)aminocarbonyl group, and a di(C 1-6 alkyl)amino group) or an optionally substituted heteroaryl group (the heteroaryl is a 5- or 6-membered ring; the heteroatom(s) on the ring of the heteroaryl group is 1 or 2 nitrogen atoms, and the ring optionally further contains one nitrogen atom, oxygen atom, or sulfur atom; and the substituent(s) is 1 or 2 identical or different groups selected from the group consisting of a halogen atom, a C 1-6 alkyl group, a C 3-7 cycloalkyl group, a trifluoromethyl group, a difluoromethoxy group, a trifluoromethoxy group, a cyano group, a C 1-6 alkoxy group, a C 3-7 cycloalkoxy group, a phenyl group, a C 2-7 alkoxycarbonyl group, a benzyloxycarbonyl group, a di(C 1-6 alkyl)aminocarbonyl group, and a di(C 1-6 alkyl)amino group), and R 1 represents a hydrogen atom or a hydroxy group.
A method for controlling a temperature rate of a component in a steam turbine system, the method comprising: determining, via a processor, a commanded temperature rate for the component of the steam turbine system said commanded temperature rate being based at least in part on receiving or deriving temperature rate setpoints forming one of a stepped temperature rate or ramped temperature rate; determining, via the processor and a number of sensors, a measured temperature rate for the component of the steam turbine system; determining, via the processor, a variable multiplier based at least in part on the commanded temperature rate and the measured temperature rate; and deriving, via the processor, a multiplied temperature rate command by applying the variable multiplier to the commanded temperature rate. determining, via a processor, a commanded temperature rate for the component of the steam turbine system said commanded temperature rate being based at least in part on receiving or deriving temperature rate setpoints forming one of a stepped temperature rate or ramped temperature rate; determining, via the processor and a number of sensors, a measured temperature rate for the component of the steam turbine system; determining, via the processor, a variable multiplier based at least in part on the commanded temperature rate and the measured temperature rate; and deriving, via the processor, a multiplied temperature rate command by applying the variable multiplier to the commanded temperature rate.