A system for treating a vessel of a patient, comprising: a first instrument sized and shaped for introduction into the vessel of the patient; wherein the first instrument includes at least one element configured to monitor pressure within the vessel; a processing unit in communication with the first instrument, the processing unit configured to: obtain pressure measurements from the first instrument while the first instrument is moved longitudinally through the vessel of the patient from a first position to a second position; display an image of the vessel including visualization based on the obtained pressure measurements; allow the user of the system to modify the image of the vessel to simulate one or more treatment options based on the obtained pressure measurements; wherein the treatment options include angioplasty, deploying one or more stents, applying a pharmaceutical agent, and combinations thereof; allow the user of the system to select one of the simulated treatment options as an identified treatment option; and characterized in that the processing unit is further configured to: display on a user display a current location of one or more treatment devices within the vessel along with a desired location of the one or more treatment devices within the vessel based on the identified treatment option, and along with a corresponding estimated treatment value associated with a deployment of the one or more treatment devices at the current location in the vessel; wherein the estimated treatment value is based on an estimated pressure ratio value associated with the treatment of the vessel. a first instrument sized and shaped for introduction into the vessel of the patient; wherein the first instrument includes at least one element configured to monitor pressure within the vessel; a processing unit in communication with the first instrument, the processing unit configured to: obtain pressure measurements from the first instrument while the first instrument is moved longitudinally through the vessel of the patient from a first position to a second position; display an image of the vessel including visualization based on the obtained pressure measurements; allow the user of the system to modify the image of the vessel to simulate one or more treatment options based on the obtained pressure measurements; wherein the treatment options include angioplasty, deploying one or more stents, applying a pharmaceutical agent, and combinations thereof; allow the user of the system to select one of the simulated treatment options as an identified treatment option; and characterized in that the processing unit is further configured to: display on a user display a current location of one or more treatment devices within the vessel along with a desired location of the one or more treatment devices within the vessel based on the identified treatment option, and along with a corresponding estimated treatment value associated with a deployment of the one or more treatment devices at the current location in the vessel; wherein the estimated treatment value is based on an estimated pressure ratio value associated with the treatment of the vessel. obtain pressure measurements from the first instrument while the first instrument is moved longitudinally through the vessel of the patient from a first position to a second position; display an image of the vessel including visualization based on the obtained pressure measurements; allow the user of the system to modify the image of the vessel to simulate one or more treatment options based on the obtained pressure measurements; wherein the treatment options include angioplasty, deploying one or more stents, applying a pharmaceutical agent, and combinations thereof; allow the user of the system to select one of the simulated treatment options as an identified treatment option; and characterized in that the processing unit is further configured to: display on a user display a current location of one or more treatment devices within the vessel along with a desired location of the one or more treatment devices within the vessel based on the identified treatment option, and along with a corresponding estimated treatment value associated with a deployment of the one or more treatment devices at the current location in the vessel; wherein the estimated treatment value is based on an estimated pressure ratio value associated with the treatment of the vessel.