An apparatus for delivering and deploying a closure element to an opening formed in a body lumen, said apparatus comprising: a closure element configured to resiliently deform between a natural, substantially planar configuration and a substantially tubular configuration, and further configured to substantially radially displace between a reduced substantially tubular configuration and an expanded substantially tubular configuration having a greater cross-sectional dimension than the reduced substantially tubular configuration; and a delivery assembly positionable through tissue and into said opening in the body lumen, and having a distal locator portion and a carrier portion oriented proximal to said distal locator portion, a proximal end of the distal locator portion being fixed relative to a distal end of the carrier portion by an intermediate support region, the distal locator portion including a distal obturator, and the carrier portion including a proximal obturator, each of said distal obturator and said proximal obturator being selectively expandable to an expanded state and selectively contractible from said expanded state to an unexpanded state, said distal obturator being configured to selectably engage said body lumen adjacent to said opening, and said carrier portion being configured to carry and support said closure element in the reduced substantially tubular configuration with said proximal obturator in said unexpanded state, and further configured to urge said closure element toward the expanded substantially tubular configuration for deployment thereof when said proximal obturator is selectively expanded to said expanded state, said closure element being oriented to engage said tissue when deployed in the expanded substantially tubular configuration, and to return toward said natural, substantially planar configuration such that the engaged tissue is drawn substantially closed. a closure element configured to resiliently deform between a natural, substantially planar configuration and a substantially tubular configuration, and further configured to substantially radially displace between a reduced substantially tubular configuration and an expanded substantially tubular configuration having a greater cross-sectional dimension than the reduced substantially tubular configuration; and a delivery assembly positionable through tissue and into said opening in the body lumen, and having a distal locator portion and a carrier portion oriented proximal to said distal locator portion, a proximal end of the distal locator portion being fixed relative to a distal end of the carrier portion by an intermediate support region, the distal locator portion including a distal obturator, and the carrier portion including a proximal obturator, each of said distal obturator and said proximal obturator being selectively expandable to an expanded state and selectively contractible from said expanded state to an unexpanded state, said distal obturator being configured to selectably engage said body lumen adjacent to said opening, and said carrier portion being configured to carry and support said closure element in the reduced substantially tubular configuration with said proximal obturator in said unexpanded state, and further configured to urge said closure element toward the expanded substantially tubular configuration for deployment thereof when said proximal obturator is selectively expanded to said expanded state, said closure element being oriented to engage said tissue when deployed in the expanded substantially tubular configuration, and to return toward said natural, substantially planar configuration such that the engaged tissue is drawn substantially closed.