A hollow fiber degassing module which includes a hollow fiber membrane bundle obtained by bundling a plurality of hollow fiber membranes in a cylindrical shape and a cylindrical body receiving the hollow fiber membrane bundle and extending in an axial direction and is configured to degas a liquid by supplying the liquid to the outside of the hollow fiber membrane and depressurizing the inside of the hollow fiber membrane, wherein a hollow fiber membrane packing ratio which is a ratio of a sum of an apparent cross-sectional area of the hollow fiber membrane with respect to an apparent cross-sectional area of the hollow fiber membrane bundle is in a range of 43% or less, and 20% or more, the cylindrical body is opened at both end portions (5a, 5b) in the axial direction, the hollow fiber membrane bundle includes a membrane bundle hollow portion located at the center of the hollow fiber membrane bundle in the radial direction, one membrane bundle end portion of the hollow fiber membrane bundle is fixed to one opening end portion of the cylindrical body by a sealing portion and the other membrane bundle end portion of the hollow fiber membrane bundle is fixed to the other opening end portion of the cylindrical body by a sealing portion, the sealing portion is charged to an entire area other than the membrane bundle hollow portion in a cross-section perpendicular to the axial direction of the cylindrical body and is provided with a communication port which communicates the membrane bundle hollow portion with the outside of the cylindrical body, the sealing portion is charged to an entire area other than the inside of the hollow fiber membrane in a cross-section perpendicular to the axial direction of the cylindrical body, a side wall of the cylindrical body is provided with a discharge port formed near the other opening end portion in relation to the center in the axial direction of the cylindrical body, and the sealing portion fixes the one membrane bundle end portion of the hollow fiber membrane bundle to the cylindrical body so that the center axis of one membrane bundle end portion matches the center axis of the cylindrical body, characterized in that the sealing portion fixes the other membrane bundle end portion of the hollow fiber membrane bundle to the cylindrical body so that the center axis of the other membrane bundle end portion of the hollow fiber membrane bundle is eccentric to the opposite side to the discharge port with respect to the center axis of the cylindrical body. wherein a hollow fiber membrane packing ratio which is a ratio of a sum of an apparent cross-sectional area of the hollow fiber membrane with respect to an apparent cross-sectional area of the hollow fiber membrane bundle is in a range of 43% or less, and 20% or more, the cylindrical body is opened at both end portions (5a, 5b) in the axial direction, the hollow fiber membrane bundle includes a membrane bundle hollow portion located at the center of the hollow fiber membrane bundle in the radial direction, one membrane bundle end portion of the hollow fiber membrane bundle is fixed to one opening end portion of the cylindrical body by a sealing portion and the other membrane bundle end portion of the hollow fiber membrane bundle is fixed to the other opening end portion of the cylindrical body by a sealing portion, the sealing portion is charged to an entire area other than the membrane bundle hollow portion in a cross-section perpendicular to the axial direction of the cylindrical body and is provided with a communication port which communicates the membrane bundle hollow portion with the outside of the cylindrical body, the sealing portion is charged to an entire area other than the inside of the hollow fiber membrane in a cross-section perpendicular to the axial direction of the cylindrical body, a side wall of the cylindrical body is provided with a discharge port formed near the other opening end portion in relation to the center in the axial direction of the cylindrical body, and the sealing portion fixes the one membrane bundle end portion of the hollow fiber membrane bundle to the cylindrical body so that the center axis of one membrane bundle end portion matches the center axis of the cylindrical body, characterized in that the sealing portion fixes the other membrane bundle end portion of the hollow fiber membrane bundle to the cylindrical body so that the center axis of the other membrane bundle end portion of the hollow fiber membrane bundle is eccentric to the opposite side to the discharge port with respect to the center axis of the cylindrical body.