A surgical system, comprising: a test end effector devoid of fasteners (400, 500) including a test jaw assembly having a pair of jaws configured to clamp about tissue and at least one sensor configured to measure at least one tissue property; and a plurality of treatment end effectors; and a handle assembly configured to selectively couple to the test end effector devoid of fasteners (400, 500) or one of the plurality of treatment end effectors, the handle assembly including: a drive assembly (360, 560); a motor operatively coupled to the drive assembly; and a controller operatively coupled to the motor, wherein the controller is configured to detect the test end effector devoid of fasteners (400, 500), and said controller is also configured to control operation of the motor to actuate the test end effector devoid of fasteners to measure the at least one tissue property and to determine and indicate, based on the at least one tissue property, at least one suitable treatment end effector from among the plurality of treatment end effectors for attachment to the handle assembly to perform a surgical function, wherein said handle assembly includes a user interface device coupled to the controller, wherein said user interface device outputs an indicia corresponding to the at least one suitable treatment end effector, wherein said indicia is selected from the group consisting of a color, an identification number, an audio tone, and combinations thereof. a test end effector devoid of fasteners (400, 500) including a test jaw assembly having a pair of jaws configured to clamp about tissue and at least one sensor configured to measure at least one tissue property; and a plurality of treatment end effectors; and a handle assembly configured to selectively couple to the test end effector devoid of fasteners (400, 500) or one of the plurality of treatment end effectors, the handle assembly including: a drive assembly (360, 560); a motor operatively coupled to the drive assembly; and a controller operatively coupled to the motor, wherein the controller is configured to detect the test end effector devoid of fasteners (400, 500), and said controller is also configured to control operation of the motor to actuate the test end effector devoid of fasteners to measure the at least one tissue property and to determine and indicate, based on the at least one tissue property, at least one suitable treatment end effector from among the plurality of treatment end a drive assembly (360, 560); a motor operatively coupled to the drive assembly; and a controller operatively coupled to the motor, wherein the controller is configured to detect the test end effector devoid of fasteners (400, 500), and said controller is also configured to control operation of the motor to actuate the test end effector devoid of fasteners to measure the at least one tissue property and to determine and indicate, based on the at least one tissue property, at least one suitable treatment end effector from among the plurality of treatment end effectors for attachment to the handle assembly to perform a surgical function, wherein said handle assembly includes a user interface device coupled to the controller, wherein said user interface device outputs an indicia corresponding to the at least one suitable treatment end effector, wherein said indicia is selected from the group consisting of a color, an identification number, an audio tone, and combinations thereof.