mhurhangee/ep-ind-claims huggingface dataset:
A compound of Formula I, or a pharmaceutically acceptable salt thereof, wherein: R 1 is chosen from -C NH and -N C R 9; R 2 is chosen from aryl, heteroaryl, and heterocycloalkyl, each of which is optionally substituted with 1 to 3 substituents independently chosen from halo, alkyl, cycloalkyl, haloalkyl, hydroxyl, alkoxy, and nitrile; A is chosen from aryl and heteroaryl; R 3 and R 4 are independently chosen from hydrogen, alkyl, halo, NHSO 2 R 10, C NR 11 R 12, NR 11 R 12, nitrile, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, aralkyl, and heteroaralkyl, each of which is optionally substituted with 1 to 3 substituents independently chosen from halo, alkyl, cycloalkyl, haloalkyl, hydroxyl, alkoxy, aryl, heteroaryl, and nitrile, wherein alkyl and alkoxy are optionally substituted with amino, (alkyl)amino or di(alkyl)amino; for each occurrence, R 5, R 6, R 7, and R 8 are independently chosen from hydrogen and lower alkyl; R 9 is chosen from hydrogen and lower alkyl; R 10 is chosen from lower alkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl; R 11 and R 12 are independently chosen from hydrogen, lower alkyl, alkoxy, lower haloalkyl and cycloalkyl wherein alkyl and alkoxy are optionally substituted with amino, (alkyl)amino or di(alkyl)amino, and m and m' are independently chosen from 0, 1, 2, 3 and 4, provided that 2 ≤ (m + m') ≤ 4; wherein lower alkyl is an alkyl group having 1 to 6 carbons. R 1 is chosen from -C NH and -N C R 9; R 2 is chosen from aryl, heteroaryl, and heterocycloalkyl, each of which is optionally substituted with 1 to 3 substituents independently chosen from halo, alkyl, cycloalkyl, haloalkyl, hydroxyl, alkoxy, and nitrile; A is chosen from aryl and heteroaryl; R 3 and R 4 are independently chosen from hydrogen, alkyl, halo, NHSO 2 R 10, C NR 11 R 12, NR 11 R 12, nitrile, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, aralkyl, and heteroaralkyl, each of which is optionally substituted with 1 to 3 substituents independently chosen from halo, alkyl, cycloalkyl, haloalkyl, hydroxyl, alkoxy, aryl, heteroaryl, and nitrile, wherein alkyl and alkoxy are optionally substituted with amino, (alkyl)amino or di(alkyl)amino; for each occurrence, R 5, R 6, R 7, and R 8 are independently chosen from hydrogen and lower alkyl; R 9 is chosen from hydrogen and lower alkyl; R 10 is chosen from lower alkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl; R 11 and R 12 are independently chosen from hydrogen, lower alkyl, alkoxy, lower haloalkyl and cycloalkyl wherein alkyl and alkoxy are optionally substituted with amino, (alkyl)amino or di(alkyl)amino, and m and m' are independently chosen from 0, 1, 2, 3 and 4, provided that 2 ≤ (m + m') ≤ 4; wherein lower alkyl is an alkyl group having 1 to 6 carbons.
A compound of a Formula I: wherein: R 1 is H; Z is O; R 2 and R 3 are each independently selected from H and D (deuterium); and each of R 4 to R 14 is independently selected from Hand D; in free or salt form, provided that at least R 2 and R 3 are D, or at least R 8 and R 9 are D, or at least all four of R 4 to R 7 are D; wherein the compound has greater than 50% incorporation of deuterium at each of the indicated D positions of the structure. R 1 is H; Z is O; R 2 and R 3 are each independently selected from H and D (deuterium); and each of R 4 to R 14 is independently selected from Hand D; in free or salt form, provided that at least R 2 and R 3 are D, or at least R 8 and R 9 are D, or at least all four of R 4 to R 7 are D; wherein the compound has greater than 50% incorporation of deuterium at each of the indicated D positions of the structure.
A processor-based method of generating haptic effects, comprising: receiving haptic permissions settings for a user; associating the haptic permissions settings with permitted haptic parameter values for the user; receiving an incoming signal, the incoming signal including haptic parameters; modifying the haptic parameters based on the permitted haptic parameter values by mapping the haptic parameters of the incoming signal to the permitted haptic parameter values; generating a haptic signal based on the modified haptic parameters; and outputting the haptic signal to a haptic output device to generate haptic effects for the user. receiving haptic permissions settings for a user; associating the haptic permissions settings with permitted haptic parameter values for the user; receiving an incoming signal, the incoming signal including haptic parameters; modifying the haptic parameters based on the permitted haptic parameter values by mapping the haptic parameters of the incoming signal to the permitted haptic parameter values; generating a haptic signal based on the modified haptic parameters; and outputting the haptic signal to a haptic output device to generate haptic effects for the user.
A travel control method for a vehicle (V 0) for executing autonomous lane change control of the vehicle (V 0), characterized by when, before performing the autonomous lane change control, presenting a driver with lane change information as to whether or not to accept execution of the autonomous lane change control and detecting, in response to presentation of the lane change information, an acceptance input made by the driver indicating that the driver accepts the execution of the autonomous lane change control, the travel control method comprising: upon execution of autonomous control of two or more successive lane changes, before performing the two or more successive lane changes, presenting the driver with first lane change information as to whether or not to accept the execution of the autonomous control of the two or more successive lane changes; when detecting, in response to presentation of the first lane change information, a first acceptance input made by the driver indicating that the driver accepts the execution of the autonomous control of the two or more successive lane changes, executing first autonomous lane change control; after executing the first autonomous lane change control, presenting the driver with second lane change information as to whether or not to accept execution of the autonomous lane change control after the first lane change; and when detecting, in response to presentation of the second lane change information, a second acceptance input made by the driver indicating that the driver accepts the execution of the autonomous lane change control after the first lane change, executing the autonomous lane change control after the first lane change, wherein an action load, of the driver, of the second acceptance input is set smaller than an action load, of the driver, of the first acceptance input. upon execution of autonomous control of two or more successive lane changes, before performing the two or more successive lane changes, presenting the driver with first lane change information as to whether or not to accept the execution of the autonomous control of the two or more successive lane changes; when detecting, in response to presentation of the first lane change information, a first acceptance input made by the driver indicating that the driver accepts the execution of the autonomous control of the two or more successive lane changes, executing first autonomous lane change control; after executing the first autonomous lane change control, presenting the driver with second lane change information as to whether or not to accept execution of the autonomous lane change control after the first lane change; and when detecting, in response to presentation of the second lane change information, a second acceptance input made by the driver indicating that the driver accepts the execution of the autonomous lane change control after the first lane change, executing the autonomous lane change control after the first lane change, wherein an action load, of the driver, of the second acceptance input is set smaller than an action load, of the driver, of the first acceptance input.
A process for separation of components in a biomass catalytic pyrolysis process effluent, comprising steps: a) fractionating the biomass catalytic pyrolysis effluent to produce a naphthalene-rich oil effluent typically boiling in a temperature range of from about 200 to about 575°C, a phenolic oil effluent typically boiling in a temperature range from 80 to 220°C, and a gaseous effluent comprising off gas, water and BTX, and b) separating and partially condensing the gaseous effluent from step a) comprising off gas, water and BTX to produce a gaseous effluent comprising off gas and gaseous BTX, a liquid effluent comprising hydrocarbons including hydrocarbons selected from the group consisting of benzene, toluene, xylenes and combinations thereof, and a liquid effluent comprising water and less than 1,000 ppmw phenolic compounds. a) fractionating the biomass catalytic pyrolysis effluent to produce a naphthalene-rich oil effluent typically boiling in a temperature range of from about 200 to about 575°C, a phenolic oil effluent typically boiling in a temperature range from 80 to 220°C, and a gaseous effluent comprising off gas, water and BTX, and b) separating and partially condensing the gaseous effluent from step a) comprising off gas, water and BTX to produce a gaseous effluent comprising off gas and gaseous BTX, a liquid effluent comprising hydrocarbons including hydrocarbons selected from the group consisting of benzene, toluene, xylenes and combinations thereof, and a liquid effluent comprising water and less than 1,000 ppmw phenolic compounds.
Electrical contact arrangement comprising a test contact point and a contact-making element, which belongs to a test device, for making manual physical contact with the test contact point, wherein the test contact point is designed as a recess, the contact-making element has a contact tip which is designed in the form of a segment of a cone or sphere at least in regions, and the contact-making element has a contact region which establishes at least surface contact with the recess, characterized in that the maximum diameter of the contact tip is larger than the maximum diameter of the recess, and in that the contact tip has a first contact tip region, which is designed in the form of a segment of a cone, and a second contact tip region, which is likewise designed in the shape of a cone, wherein the smallest diameter of the second contact region is larger than the largest diameter of the first contact tip region.
A radiographing apparatus comprising: a selecting unit configured to select a target dose index for radiographing based on a radiographing imaging mode, wherein the imaging mode is an attachment state of a grid; a dose index acquiring unit configured to acquire a dose index from image data based on radiation transmitted through a subject; a calculating unit configured to calculate a deviation index of the dose index with respect to the target dose index; and a display control unit configured to display, on a display unit, the deviation index of the dose index with respect to the target dose index, wherein, in a case where a grid is attached to the radiographing apparatus, the selecting unit selects a first target dose index, and the display control unit displays, on the display unit, the first target dose index and the deviation index of the dose index with respect to the first target dose index, and wherein, in a case where the grid is not attached to the radiographing apparatus, the selecting unit selects a second target dose index, and the display control unit displays, on the display unit, the second target dose index and the deviation index of the dose index with respect to the second target dose index. a selecting unit configured to select a target dose index for radiographing based on a radiographing imaging mode, wherein the imaging mode is an attachment state of a grid; a dose index acquiring unit configured to acquire a dose index from image data based on radiation transmitted through a subject; a calculating unit configured to calculate a deviation index of the dose index with respect to the target dose index; and a display control unit configured to display, on a display unit, the deviation index of the dose index with respect to the target dose index, wherein, in a case where a grid is attached to the radiographing apparatus, the selecting unit selects a first target dose index, and the display control unit displays, on the display unit, the first target dose index and the deviation index of the dose index with respect to the first target dose index, and wherein, in a case where the grid is not attached to the radiographing apparatus, the selecting unit selects a second target dose index, and the display control unit displays, on the display unit, the second target dose index and the deviation index of the dose index with respect to the second target dose index.
A method of recording and reproducing data, comprising: writing on an information recording medium a recording unit block of a predetermined size in which valid data is included in part of the recording unit block and invalid data is padded in the remaining part of the recording unit block or reading the recording unit block from the information recording medium; and updating valid data included in the recording unit block based on padding information, wherein the recording unit block comprises a first cluster including a plurality of data units and a second cluster comprising address information regarding the plurality of data units, and wherein the second cluster further comprises the padding information indicating whether each of the plurality of data units comprises the invalid data. writing on an information recording medium a recording unit block of a predetermined size in which valid data is included in part of the recording unit block and invalid data is padded in the remaining part of the recording unit block or reading the recording unit block from the information recording medium; and updating valid data included in the recording unit block based on padding information, wherein the recording unit block comprises a first cluster including a plurality of data units and a second cluster comprising address information regarding the plurality of data units, and wherein the second cluster further comprises the padding information indicating whether each of the plurality of data units comprises the invalid data.
A portable bedside urinal comprising: a funnel for receiving urine; a hose connected to the funnel; a container connected to the hose for receiving and storing urine input at the funnel; a funnel support, located with respect to the container so that when the appliance is not in use the funnel is held upright and higher than the level of urine in the container, the funnel support being shaped substantially to circumscribe the funnel and hose so that, when the appliance is in use, the hose is guided through the funnel support and unable to escape from the funnel support, characterized in that: the funnel support is connected to the container, and the hose has a bending stiffness, defined as the force required to deform the unstressed straight hose to a U-shape with a minimum inner bending radius of 20cm, of at least 1N and not more than 10N, and the hose has a length from funnel support to funnel, when extended in use, of 200cm or less, to allow the hose to guide the funnel back into the funnel support after use. a funnel for receiving urine; a hose connected to the funnel; a container connected to the hose for receiving and storing urine input at the funnel; a funnel support, located with respect to the container so that when the appliance is not in use the funnel is held upright and higher than the level of urine in the container, the funnel support being shaped substantially to circumscribe the funnel and hose so that, when the appliance is in use, the hose is guided through the funnel support and unable to escape from the funnel support, characterized in that: the funnel support is connected to the container, and the hose has a bending stiffness, defined as the force required to deform the unstressed straight hose to a U-shape with a minimum inner bending radius of 20cm, of at least 1N and not more than 10N, and the hose has a length from funnel support to funnel, when extended in use, of 200cm or less, to allow the hose to guide the funnel back into the funnel support after use. the funnel support is connected to the container, and the hose has a bending stiffness, defined as the force required to deform the unstressed straight hose to a U-shape with a minimum inner bending radius of 20cm, of at least 1N and not more than 10N, and the hose has a length from funnel support to funnel, when extended in use, of 200cm or less, to allow the hose to guide the funnel back into the funnel support after use.
A power-generation main circuit switchgear that is configured to be arranged at a midpoint of an isolated-phase bus connecting a power generator and a main transformer and that includes a breaking unit connectable to the isolated-phase bus, the power-generation main circuit switchgear comprising: a casing with an axial direction thereof being an extending direction of the isolated-phase bus; an internal conductor (1a, 1b) that is arranged in the casing and constitutes the breaking unit; a duct that is provided on the casing separately for each phase and communicates with a space inside the casing through a plurality of vent holes (5a, 5b); and a blower arranged in the duct to blow wind in the axial direction to allow the wind to circulate inside the duct and inside the casing through the vent holes (5a, 5b), characterized in that the vent holes (5a, 5b) are formed through the duct and include a first vent hole disposed over the internal conductor (1a, 1b) of the breaking unit and on a downstream side of the blower in the axial direction, and a second vent hole provided on an upstream side of the blower in the axial direction, and wind blowing from the blower through an inside of the duct out of the first vent hole into the casing directly hits at least a part of the internal conductor (1a, 1b) in a vertical direction perpendicular to the internal conductor (1a, 1b) for cooling the internal conductor (1a, 1b). a casing with an axial direction thereof being an extending direction of the isolated-phase bus; an internal conductor (1a, 1b) that is arranged in the casing and constitutes the breaking unit; a duct that is provided on the casing separately for each phase and communicates with a space inside the casing through a plurality of vent holes (5a, 5b); and a blower arranged in the duct to blow wind in the axial direction to allow the wind to circulate inside the duct and inside the casing through the vent holes (5a, 5b), characterized in that the vent holes (5a, 5b) are formed through the duct and include a first vent hole disposed over the internal conductor (1a, 1b) of the breaking unit and on a downstream side of the blower in the axial direction, and a second vent hole provided on an upstream side of the blower in the axial direction, and wind blowing from the blower through an inside of the duct out of the first vent hole into the casing directly hits at least a part of the internal conductor (1a, 1b) in a vertical direction perpendicular to the internal conductor (1a, 1b) for cooling the internal conductor (1a, 1b).
A nasal cannula assembly (100, 1000) comprising: a breathing gas supply lumen assembly splitting into a first inspiratory gas lumen (102, 1002) and a second inspiratory gas lumen; an inspiratory gas nasal end portion (106, 108) in fluid communication with the first inspiratory gas lumen and the second inspiratory gas lumen, the inspiratory gas nasal end portion (106, 108) having a pair of nasal prongs (124, 126) extending outwardly therefrom; an expiratory gas assembly splitting into a first expiratory gas lumen (112, 1012) and a second expiratory gas lumen; an expiratory gas nasal end portion (116, 118) in fluid communication with the first expiratory gas lumen and the second expiratory gas lumen; wherein the first inspiratory gas lumen and the first expiratory gas lumen are joined along a common sidewall and wherein the second inspiratory gas lumen and the second expiratory gas lumen are joined along the common sidewall; characterized in that a passage is disposed across the inspiratory gas nasal end portion (106, 108) from the pair of nasal prongs (124, 126), the passage providing fluid communication between the inspiratory gas nasal end portion (106, 108) and the expiratory gas nasal end portion(116, 118) such that passage through the sidewall allows for direct flow of breathing gas between the breathing gas supply lumen assembly and the expiratory gas assembly. a breathing gas supply lumen assembly splitting into a first inspiratory gas lumen (102, 1002) and a second inspiratory gas lumen; an inspiratory gas nasal end portion (106, 108) in fluid communication with the first inspiratory gas lumen and the second inspiratory gas lumen, the inspiratory gas nasal end portion (106, 108) having a pair of nasal prongs (124, 126) extending outwardly therefrom; an expiratory gas assembly splitting into a first expiratory gas lumen (112, 1012) and a second expiratory gas lumen; an expiratory gas nasal end portion (116, 118) in fluid communication with the first expiratory gas lumen and the second expiratory gas lumen; wherein the first inspiratory gas lumen and the first expiratory gas lumen are joined along a common sidewall and wherein the second inspiratory gas lumen and the second expiratory gas lumen are joined along the common sidewall; characterized in that a passage is disposed across the inspiratory gas nasal end portion (106, 108) from the pair of nasal prongs (124, 126), the passage providing fluid communication between the inspiratory gas nasal end portion (106, 108) and the expiratory gas nasal end portion(116, 118) such that passage through the sidewall allows for direct flow of breathing gas between the breathing gas supply lumen assembly and the expiratory gas assembly.
Unit for producing green tyres (2; 2'), comprising: - a shaft, - a holder mounted so as to slide with respect to the shaft, - arms articulated to the holder, and - driving means that are able to drive the arms in rotation with respect to the holder independently of any sliding of the holder with respect to the shaft and regardless of the position of the arms with respect to the green tyre, characterized in that it comprises: - a ring mounted so as to be rotatable about a main axis of the shaft with respect to the holder, and - conversion means (20, 28, 42) for converting a rotation of the ring into a rotation of the arms with respect to the holder, the conversion means comprising at least one helical ramp formed on an external face of the holder, and at least one roller that bears against the ramp and is fastened to the ring. - a shaft, - a holder mounted so as to slide with respect to the shaft, - arms articulated to the holder, and - driving means that are able to drive the arms in rotation with respect to the holder independently of any sliding of the holder with respect to the shaft and regardless of the position of the arms with respect to the green tyre, characterized in that it comprises: - a ring mounted so as to be rotatable about a main axis of the shaft with respect to the holder, and - conversion means (20, 28, 42) for converting a rotation of the ring into a rotation of the arms with respect to the holder,