A mobile imaging system configured for preventing the initiation of x-rays from a radiation source, comprising: a radiation source system comprising a portable radiation source; a portable detector comprising a plurality of pixels, the pixels operable to encode output signals based on radiation wherein the portable detector is operable to receive, from through one or more positioning apertures, a plurality of radiation alignment beams from the portable radiation source for creating an alignment beam calibration image; an alignment beam calibration system comprising a communication unit, at least one processor, at least one memory and a plurality of programming instructions, the alignment beam calibration system being a configuration of components that allows the processor to compare an alignment instance image with an alignment beam calibration image, the plurality of programming instructions when executed by the at least one processor causes the at least one processors to: designate an alignment pixels' region within the calibration image, wherein the presence of overlap of these pixels with the alignment instance image generates a data property used to effect determination of alignment; receive the alignment instance image, via the communication unit, from the portable detector; detect the presence of an overlap of the alignment instance image pixels' region with the calibration image indicating that the portable detector and the radiation source are aligned; communicatively connect, via the communication unit, to the portable radiation source; if the portable detector is aligned with the radiation source within a predetermined tolerance, send, via the communication unit, a signal to the radiation source to activate and initiate imaging; and, if the portable detector is not within the predetermined tolerance during a video imaging procedure, prevent the initiation of x-rays from the radiation source. a radiation source system comprising a portable radiation source; a portable detector comprising a plurality of pixels, the pixels operable to encode output signals based on radiation wherein the portable detector is operable to receive, from through one or more positioning apertures, a plurality of radiation alignment beams from the portable radiation source for creating an alignment beam calibration image; an alignment beam calibration system comprising a communication unit, at least one processor, at least one memory and a plurality of programming instructions, the alignment beam calibration system being a configuration of components that allows the processor to compare an alignment instance image with an alignment beam calibration image, the plurality of programming instructions when executed by the at least one processor causes the at least one processors to: designate an alignment pixels' region within the calibration image, wherein the presence of overlap of these pixels with the alignment instance image generates a data property used to effect determination of alignment; receive the alignment instance image, via the communication unit, from the portable detector; detect the presence of an overlap of the alignment instance image pixels' region with the calibration image indicating that the portable detector and the radiation source are aligned; communicatively connect, via the communication unit, to the portable radiation source; if the portable detector is aligned with the radiation source within a predetermined tolerance, send, via the communication unit, a signal to the radiation source to activate and initiate imaging; and, if the portable detector is not within the predetermined tolerance during a video imaging procedure, prevent the initiation of x-rays from the radiation source. designate an alignment pixels' region within the calibration image, wherein the presence of overlap of these pixels with the alignment instance image generates a data property used to effect determination of alignment; receive the alignment instance image, via the communication unit, from the portable detector; detect the presence of an overlap of the alignment instance image pixels' region with the calibration image indicating that the portable detector and the radiation source are aligned; communicatively connect, via the communication unit, to the portable radiation source; if the portable detector is aligned with the radiation source within a predetermined tolerance, send, via the communication unit, a signal to the radiation source to activate and initiate imaging; and, if the portable detector is not within the predetermined tolerance during a video imaging procedure, prevent the initiation of x-rays from the radiation source.