mhurhangee/ep-ind-claims huggingface dataset:
A medical instrument of bipolar design comprising at least two electrodes (10, 16) being held by electrode carriers (6, 12) movable relative to each other which can be charged with HF current via a respective feed line, characterized by a safety switch mechanism (26, 28, 34) arranged in the area of at least one of the electrode carriers (6, 12) and interconnected in at least one of the feed lines, wherein the safety switch mechanism (26, 28, 34) is brought into an OFF or disconnect position only upon transferring a first, rim-shaped electrode carrier into the out-of-operation position, whereby HF current supply to the electrode associated with the feed line is disconnected, having an endoscope shaft, the distal end piece of which forms the other electrode carrier, at which the substantially annular first electrode is placed at the end face, and an electrode cap including a pin supported to be axially movable in the distal end piece of the endoscope shaft, wherein the electrode cap supports a second, substantially annular electrode interacting with the first electrode on a side facing the end piece, the electrode cap consisting of the rim-shaped electrode carrier which is centrically supported on the now tubular pin in a hinge-like manner so as to be swiveled into an operating position substantially in parallel to the end face of the distal shaft end piece and into an out-of-function position at an angle of more than 0° with respect to the end face of the distal shaft end piece, wherein the safety switch mechanism (26, 28, 34) is mechanically coupled to the pin such that at a position of the rim-shaped electrode carrier outside of its operating position, the at least one feed line to the electrode held by the rim-shaped electrode carrier is disconnected, wherein the rim-shaped electrode carrier is pivoted relative to the pin by means of an actuating rod supported to be axially movable in the pin, the actuating rod being coupled to the rim-shaped electrode carrier via a joint lever so as to transfer an axial movement of the actuating rod along the pin into a pivoting movement of the rim-shaped electrode carrier about the pin, and wherein the actuating rod is electrically connected to the electrode held by the rim-shaped electrode carrier and thus constitutes a portion of the HF feed line, wherein at the tubular pin a contact is arranged which at a predetermined axial position of the actuating rod relative to the pin, in which the rim-shaped electrode carrier is unfolded in the operating position, enters into electric contact with the actuating rod or a contact provided on the latter.
A method for a rational cell culturing process comprising: a) providing a mammalian host cell, b) culturing said cell according to a process A, c) culturing said cell according to a process B, which is different from process A, d) employing a comparative method suitable to distinguish between the different performance levels of said cell in process A versus process B, e) identifying biological functions and metabolic pathways which relate to the two different processes A and B and their respective performance levels, f) selecting components of deregulated metabolic pathways according to the following criteria: i. signal intensity values ≥ 40, ii. p-value ≤ 0.1, iii. log2 fold change of |FC| ≥ 1.5, iv. FC criteria (iii) to be satisfied for at least one time point of the cultivation time, g) identifying at least one deregulated component of the lipid metabolism, h) cultivating said cell of step a) according to a process C, which is different from process A and process B, whereby said cultivation process C is adjusted, by altering the lipid media composition. a) providing a mammalian host cell, b) culturing said cell according to a process A, c) culturing said cell according to a process B, which is different from process A, d) employing a comparative method suitable to distinguish between the different performance levels of said cell in process A versus process B, e) identifying biological functions and metabolic pathways which relate to the two different processes A and B and their respective performance levels, f) selecting components of deregulated metabolic pathways according to the following criteria: i. signal intensity values ≥ 40, ii. p-value ≤ 0.1, iii. log2 fold change of |FC| ≥ 1.5, iv. FC criteria (iii) to be satisfied for at least one time point of the cultivation time, i. signal intensity values ≥ 40, ii. p-value ≤ 0.1, iii. log2 fold change of |FC| ≥ 1.5, iv. FC criteria (iii) to be satisfied for at least one time point of the cultivation time, g) identifying at least one deregulated component of the lipid metabolism, h) cultivating said cell of step a) according to a process C, which is different from process A and process B, whereby said cultivation process C is adjusted, by altering the lipid media composition.
An isolated nucleic acid encoding for a protein conferring resistance to OWBM, wherein the nucleic acid comprises at least one of the groups consisting of: a) Group 1: i. A nucleic acid comprising SEQ ID NO:4 or 5, or ii. A nucleic acid encoding an amino acid sequence comprising SEQ ID NO:6, or iii. A nucleic acid encoding an amino-acid sequence comprising at least one CC motif, one NBSARC motif and one LRR motif and wherein the sequence encoding the LRR motif is having at least 82% identity with the nucleic acid fragment as depicted in SEQ ID NO:8, and b. Group 2: i. A nucleic acid comprising SEQ ID NO:1 or 2, or ii. A nucleic acid encoding an amino acid sequence comprising SEQ ID NO:3, or iii. A nucleic acid encoding an amino-acid sequence comprising at least one CC motif, one NBS-ARC motif and one LRR motif, and wherein the sequence encoding the LRR motif is having at least 78% identity with the nucleic acid fragment as depicted in SEQ ID NO:7, a) Group 1: i. A nucleic acid comprising SEQ ID NO:4 or 5, or ii. A nucleic acid encoding an amino acid sequence comprising SEQ ID NO:6, or iii. A nucleic acid encoding an amino-acid sequence comprising at least one CC motif, one NBSARC motif and one LRR motif and wherein the sequence encoding the LRR motif is having at least 82% identity with the nucleic acid fragment as depicted in SEQ ID NO:8, and i. A nucleic acid comprising SEQ ID NO:4 or 5, or ii. A nucleic acid encoding an amino acid sequence comprising SEQ ID NO:6, or iii. A nucleic acid encoding an amino-acid sequence comprising at least one CC motif, one NBSARC motif and one LRR motif and wherein the sequence encoding the LRR motif is having at least 82% identity with the nucleic acid fragment as depicted in SEQ ID NO:8, and b. Group 2: i. A nucleic acid comprising SEQ ID NO:1 or 2, or ii. A nucleic acid encoding an amino acid sequence comprising SEQ ID NO:3, or iii. A nucleic acid encoding an amino-acid sequence comprising at least one CC motif, one NBS-ARC motif and one LRR motif, and wherein the sequence encoding the LRR motif is having at least 78% identity with the nucleic acid fragment as depicted in SEQ ID NO:7, i. A nucleic acid comprising SEQ ID NO:1 or 2, or ii. A nucleic acid encoding an amino acid sequence comprising SEQ ID NO:3, or iii. A nucleic acid encoding an amino-acid sequence comprising at least one CC motif, one NBS-ARC motif and one LRR motif, and wherein the sequence encoding the LRR motif is having at least 78% identity with the nucleic acid fragment as depicted in SEQ ID NO:7,
Cooking device (100; 200; 300; 400) comprising a cooking support member (110; 210; 310; 410) having a cooking face (111; 311) and a heating face (112; 212; 312; 412), a layer of anisotropic graphite (124; 224; 324; 424) being encapsulated between an aluminium layer (121; 221; 321; 421) and another aluminium layer (115; 215; 315; 415), the aluminium layer (121; 221; 321; 421) and the layer of anisotropic graphite (124; 224; 324; 424) belonging to a multi-layer diffuser base (120; 220; 320; 420), the layer of anisotropic graphite (124; 224; 324; 424) being adjacent to the heating face (112; 212; 312; 412), and the other aluminium layer (115; 215; 315; 415) belonging to the heating face (112; 212; 312; 412), characterised in that the aluminium layer (121; 221; 321; 421) is metallurgically joined to the heating face (112; 212; 312; 412) leaving one portion of the heating face (112; 212; 312; 412) free around the aluminium layer (121; 221; 321; 421).
An ultrasound medical diagnosis apparatus comprising: a main body; a chair unit movably supported by the main body and on which an object is positioned and comprising an upper body support, a seat, and a leg rest sequentially arranged in one direction and connected to one another; a diagnosis part that is movably connected to the main body and is spaced apart from the chair unit by a preset first distance in one plane and may be used by a user to manipulate the medical diagnosis apparatus; a controller configured to generate control signals based on first body information of the subject, which is acquired based on input ID information, for moving the ultrasound diagnosis device, for moving the diagnosis part, and for changing the shapes of and moving the chair; a first driving device configured to generate a driving force for moving the diagnosis part according to the control signals; a second driving device configured to generate a driving force for moving the the ultrasound diagnosis device according to the control signals; a third driving unit for changing the shapes of and moving the chair unit according to the control signals; wherein the shapes and position of the chair unit and the positions of the ultrasound diagnosis device and the diagnosis part are changed from an initial state to a diagnostic state according to the control signals. a main body; a chair unit movably supported by the main body and on which an object is positioned and comprising an upper body support, a seat, and a leg rest sequentially arranged in one direction and connected to one another; a diagnosis part that is movably connected to the main body and is spaced apart from the chair unit by a preset first distance in one plane and may be used by a user to manipulate the medical diagnosis apparatus; a controller configured to generate control signals based on first body information of the subject, which is acquired based on input ID information, for moving the ultrasound diagnosis device, for moving the diagnosis part, and for changing the shapes of and moving the chair; a first driving device configured to generate a driving force for moving the diagnosis part according to the control signals; a second driving device configured to generate a driving force for moving the the ultrasound diagnosis device according to the control signals; a third driving unit for changing the shapes of and moving the chair unit according to the control signals; wherein the shapes and position of the chair unit and the positions of the ultrasound diagnosis device and the diagnosis part are changed from an initial state to a diagnostic state according to the control signals.
A high gas barrier composition usable as a coating or layer on an article, said composition including a blend of polyetheramine resin and at least one additive being a highly hydroxylated organic compound including a hydroxyl-to-carbon ratio of 0.5 or greater and being present in a weight percentage of said composition for increasing the gas barrier properties of the polyetheramine resin by at least 20 percent in comparison to the gas barrier properties of approximately the same weight of polyetheramine resin but without the additive and said weight percentage being in the range of 0.5 to at least 40.
An initialising system for a refrigerant compressor unit, including a refrigerant compressor, an electrical drive motor for the refrigerant compressor and a compressor controller that determines the voltage and speed of the drive motor on the basis of sets of configuration parameters (VKx, MKx, KKx) loaded into this compressor controller and controls the drive motor accordingly, wherein the initialising system has a compressor data memory, in which compressor data relating to respectively possible refrigerant compressors are stored, and a motor data memory, in which motor data relating to possible drive motors are stored, wherein the initialising system has a processor for performing the initialising, a display unit and an input unit, wherein during initialisation the display unit and the input unit serve to determine the refrigerant compressor and the drive motor, and wherein the processor uses the compressor data (VDx) of the determined refrigerant compressor (Vx) and uses the motor data (MDx) of the determined drive motor (Mx) to generate compressor configuration parameters (VKx) and motor configuration parameters (MKx) and loads them into the compressor controller for the purpose of operating the drive motor.
A method for error correction of nucleic acid molecules, said method comprising: (a) obtaining a first plurality of double-stranded nucleic acid molecules comprising i) nucleic acid molecules of a desired sequence and, ii) nucleic acid molecules having at least one nucleotide mismatch relative to the desired sequence; (b) fragmenting said plurality of double-stranded nucleic acid molecules by reacting said nucleic acid molecules with at least one CEL I and/or CEL II enzyme having mismatch endonuclease activity; (c) removing said at least one nucleotide mismatch by reacting said fragmented double-stranded nucleic acid molecules of step (b) with exonuclease III to provide a fragmented error-free double-stranded nucleic acid molecule of the desired sequence; and (d) assembling a second plurality of double-stranded nucleic acid molecules comprising said fragmented error-free double-stranded nucleic acid molecule of step (c), wherein the second plurality of double-stranded nucleic acid molecules has a higher proportion of nucleic acid molecules having the desired sequence and a decreased frequency of nucleotide mismatches as compared to said first plurality of double-stranded nucleic acid molecules; further comprising a step prior to step (a) of amplifying double-stranded nucleic acid molecules of a desired sequence; and wherein the steps are carried out in the sequential order as listed (a) obtaining a first plurality of double-stranded nucleic acid molecules comprising i) nucleic acid molecules of a desired sequence and, ii) nucleic acid molecules having at least one nucleotide mismatch relative to the desired sequence; i) nucleic acid molecules of a desired sequence and, ii) nucleic acid molecules having at least one nucleotide mismatch relative to the desired sequence; (b) fragmenting said plurality of double-stranded nucleic acid molecules by reacting said nucleic acid molecules with at least one CEL I and/or CEL II enzyme having mismatch endonuclease activity; (c) removing said at least one nucleotide mismatch by reacting said fragmented double-stranded nucleic acid molecules of step (b) with exonuclease III to provide a fragmented error-free double-stranded nucleic acid molecule of the desired sequence; and (d) assembling a second plurality of double-stranded nucleic acid molecules comprising said fragmented error-free double-stranded nucleic acid molecule of step (c), wherein the second plurality of double-stranded nucleic acid molecules has a higher proportion of nucleic acid molecules having the desired sequence and a decreased frequency of nucleotide mismatches as compared to said first plurality of double-stranded nucleic acid molecules; further comprising a step prior to step (a) of amplifying double-stranded nucleic acid molecules of a desired sequence; and wherein the steps are carried out in the sequential order as listed
A method of bonding a semiconductor structure to an electronic substrate to effect both a mechanical bond and a selectively patterned conductive bond, comprising the steps of: first mechanically bonding a semiconductor structure comprising a pixel detector structure comprising a radiation detector having a pixellated structure to define a plurality of individual pixels across an area of the detector material to an electronic substrate by means of a bonding layer (7; 17); providing gaps (11; 18) in the bonding layer (7; 17) corresponding to a desired conductive bond pattern; providing vias through the electronic substrate positioned at the gaps in the bonding layer (7; 17); causing electrically conductive material (13; 16, 21) to contact the semiconductor structure exposed through the vias; optionally and to the extent necessitated by the nature of the conductive material, further treating the conductive material to complete a conductive connection between the semiconductor structure and the substrate. first mechanically bonding a semiconductor structure comprising a pixel detector structure comprising a radiation detector having a pixellated structure to define a plurality of individual pixels across an area of the detector material to an electronic substrate by means of a bonding layer (7; 17); providing gaps (11; 18) in the bonding layer (7; 17) corresponding to a desired conductive bond pattern; providing vias through the electronic substrate positioned at the gaps in the bonding layer (7; 17); causing electrically conductive material (13; 16, 21) to contact the semiconductor structure exposed through the vias; optionally and to the extent necessitated by the nature of the conductive material, further treating the conductive material to complete a conductive connection between the semiconductor structure and the substrate.
Monocrystalline semiconductor wafer having an average roughness R a of at most 0.8 nm at a limiting wavelength of 250 μm, characterized by an ESFQR avg of 8 nm or less given an edge exclusion of 1 mm, the measurement fields for measuring the ESFQR avg having a radial length of 30 mm and the width of the measurement fields resulting from a uniform division into 72 sectors of equal size.
A method in a network node for obtaining a permanent device identity of a wireless device requesting authentication at said network node, the method comprising: - intercepting an authentication message from a wireless device, wherein the authentication message comprises a signaled identity of the wireless device, - extracting the signaled identity from the authentication message, - determining if the signaled identity is an alias, and when the device identity is an alias, manipulating at least one further authentication message to cause signaling of a permanent device identity in a subsequent authentication message from the wireless device, said manipulating comprising: - providing an amended authentication message by replacing the alias with a dummy identity, or by inserting a request for a permanent device identity, - forwarding the amended authentication message to an authentication server, - receiving a request from the authentication server to inquire the wireless device for the permanent device identity, and - forwarding a request for the permanent device identity to the wireless device. - intercepting an authentication message from a wireless device, wherein the authentication message comprises a signaled identity of the wireless device, - extracting the signaled identity from the authentication message, - determining if the signaled identity is an alias, and when the device identity is an alias, manipulating at least one further authentication message to cause signaling of a permanent device identity in a subsequent authentication message from the wireless device, said manipulating comprising: - providing an amended authentication message by replacing the alias with a dummy identity, or by inserting a request for a permanent device identity, - forwarding the amended authentication message to an authentication server, - receiving a request from the authentication server to inquire the wireless device for the permanent device identity, and - forwarding a request for the permanent device identity to the wireless device.
Bearing arrangement consisting of a magnetic radial bearing and a touchdown bearing for contactless support of a rotor shaft and for catching said rotor shaft of a turbomachine with an electric power output of 1000 kW and more, wherein both bearings (4, 5), in axial alignment and fixedly interconnected, are accommodated in a common bearing housing, characterized in that the bearing housing is elastically suspended with regard to a bearing bracket or with regard to a machine casing.
A method for detection of cancer cells in a sample taken from a human, the method comprising the steps of: (a-1) incubating the living cells contained in the sample taken from the human in a buffer solution containing a fluorescently labeled molecule which can be specifically taken up into a living cell to allow for uptake of the fluorescently labeled molecule, (a-2) replacing the buffer solution with a buffer solution free from the fluorescently labeled molecule to stop the uptake of the fluorescently labeled molecule, (a-3) allowing the cells to attach to a cell-attaching region on a thin glass or plastic plate, and adding the buffer solution to a buffer-solution holding region for holding the buffer solution configured to include and enclose the cell-attaching region and provided on the plate, and maintaining the cells in a viable state, the buffer-solution holding region comprising a plate side for cell adhesion and a buffer-solution holding structure configured to enclose the buffer-solution holding region, (a-4) detecting fluorescence from the fluorescently labeled molecule present inside the attached cells, and (a-5) detecting cancer cells based on the detection of fluorescence. (a-1) incubating the living cells contained in the sample taken from the human in a buffer solution containing a fluorescently labeled molecule which can be specifically taken up into a living cell to allow for uptake of the fluorescently labeled molecule, (a-2) replacing the buffer solution with a buffer solution free from the fluorescently labeled molecule to stop the uptake of the fluorescently labeled molecule, (a-3) allowing the cells to attach to a cell-attaching region on a thin glass or plastic plate, and adding the buffer solution to a buffer-solution holding region for holding the buffer solution configured to include and enclose the cell-attaching region and provided on the plate, and maintaining the cells in a viable state, the buffer-solution holding region comprising a plate side for cell adhesion and a buffer-solution holding structure configured to enclose the buffer-solution holding region, (a-4) detecting fluorescence from the fluorescently labeled molecule present inside the attached cells, and (a-5) detecting cancer cells based on the detection of fluorescence.