An intraoperative clip loading device comprising: an elongate body having a proximal portion and a distal portion and defining a longitudinal axis, the elongate body including an outer tube having a distal portion defining an opening and including an inner wall; clip retainers supported on the inner wall of the outer tube, the clip retainers defining clip retention pockets along the longitudinal axis of the elongate body, wherein each of the clip retainers includes a longitudinal portion, wherein each of the longitudinal portions includes a flexible tab having a stop surface; a plurality of ligation clips, each of the plurality of ligation clips being supported within one of the clip retention pockets and including a first beam, a second beam, and a hinge portion coupling the first beam to the second beam, each of the first and second beams (22, 24) including spaced bosses, wherein the stop surfaces of the flexible tabs of the clip retainers are positioned to engage the hinge portions of the plurality of ligation clips to prevent proximal movement of the plurality of ligation clips within the outer tube; clip locking arms supported within the distal portion of the outer tube, the clip locking arms formed of a resilient material, the clip locking arms each including a concavity configured to receive the spaced bosses of a respective one of the first and second beams (22, 24) of the ligation clips; a clip advancing member including an elongate member and a plurality of resilient fingers, each resilient finger of the plurality of resilient fingers engaging a respective one of the plurality of ligation clips, the clip advancing member movable within the outer tube from a retracted position to an advanced position to move the plurality of clips distally within the outer tube; and a guide member positioned on the distal portion of the outer tube, the guide member including diametrically opposed channels configured to receive jaws of a clip applier, wherein the clip locking arms are aligned with the opposed channels in the guide member, wherein the clip retainers are formed of a resilient material, characterised in that each of the clip retainers includes a base portion secured to the inner wall of the outer tube, the clip retainers positioned along opposite sides of the outer tube, each of the clip retainers aligned with another of the clip retainers such that two diametrically opposed clip retainers cooperate to define one of the clip retention pockets, wherein each of the clip retainers includes a transverse portion that interconnects the base portion of the clip retainers and the longitudinal portion of the clip retainers. an elongate body having a proximal portion and a distal portion and defining a longitudinal axis, the elongate body including an outer tube having a distal portion defining an opening and including an inner wall; clip retainers supported on the inner wall of the outer tube, the clip retainers defining clip retention pockets along the longitudinal axis of the elongate body, wherein each of the clip retainers includes a longitudinal portion, wherein each of the longitudinal portions includes a flexible tab having a stop surface; a plurality of ligation clips, each of the plurality of ligation clips being supported within one of the clip retention pockets and including a first beam, a second beam, and a hinge portion coupling the first beam to the second beam, each of the first and second beams (22, 24) including spaced bosses, wherein the stop surfaces of the flexible tabs of the clip retainers are positioned to engage the hinge portions of the plurality of ligation clips to prevent proximal movement of the plurality of ligation clips within the outer tube; clip locking arms supported within the distal portion of the outer tube, the clip locking arms formed of a resilient material, the clip locking arms each including a concavity configured to receive the spaced bosses of a respective one of the first and second beams (22, 24) of the ligation clips; a clip advancing member including an elongate member and a plurality of resilient fingers, each resilient finger of the plurality of resilient fingers engaging a respective one of the plurality of ligation clips, the clip advancing member movable within the outer tube from a retracted position to an advanced position to move the plurality of clips distally within the outer tube; and a guide member positioned on the distal portion of the outer tube, the guide member including diametrically opposed channels configured to receive jaws of a clip applier, wherein the clip locking arms are aligned with the opposed channels in the guide member, wherein the clip retainers are formed of a resilient material, characterised in that each of the clip retainers includes a base portion secured to the inner wall of the outer tube, the clip retainers positioned along opposite sides of the outer tube, each of the clip retainers aligned with another of the clip retainers such that two diametrically opposed clip retainers cooperate to define one of the clip retention pockets, wherein each of the clip retainers includes a transverse portion that interconnects the base portion of the clip retainers and the longitudinal portion of the clip retainers.