mhurhangee/ep-ind-claims huggingface dataset:
A process for operating a fluidized bed reactor system consisting of at least two fluidized bed reactors for carrying out chemical reactions, a first reactor and a second reactor (1, 2) being operated as circulating fluidized beds by introducing fluid via at least one fluid inlet (11, 12) in the bottom of the respective reactor (1, 2) and/or immediately above said bottom to generate a fast fluidized particle bed and by transporting fluidized bed particles via a particle line, which comprises a particle separator, from the first to the second reactor and by returning them via a draining particle line located in the lower half of the second reactor into the first reactor and by returning them via a particle feedback line, which comprises a particle separator, from the second reactor, characterized in that reaction zones (9, 10, 22) separated by one or more flow controllers (18, 21) in the form of constrictions of the reactor cross-section for carrying out chemical reactions are provided at least in the second reactor, each being situated above one flow controller (18, 21), and in that the particle line opens into the second reactor above at least one flow controller, so that particles in the reaction zones (10, 22) above any flow controller which is situated below the opening of said particle line are transported in countercurrent flow to the fluid flow; and in that particles located below at least one flow controller which is provided in the second reactor are introduced into the second reactor and/or into the lower half of the first reactor via said particle feedback line, so that a portion of these particles in the second reactor move upwards again and are thus transported in countercurrent flow to particles introduced from the first reactor via the particle line.
Method for producing cells having at least one characteristic of human hepatocytes, said method comprising the steps of: (a) seeding human monocytes in a culture vessel in a cell culture medium; (b) culturing the monocytes in a cell culture medium comprising interleukin 3 (IL-3) and adenosine; and (c) culturing the cells simultaneously with or subsequent to step (b) in a cell culture medium comprising fibroblast growth factor 4 (FGF-4). (a) seeding human monocytes in a culture vessel in a cell culture medium; (b) culturing the monocytes in a cell culture medium comprising interleukin 3 (IL-3) and adenosine; and (c) culturing the cells simultaneously with or subsequent to step (b) in a cell culture medium comprising fibroblast growth factor 4 (FGF-4).
A flushable intermittent urinary catheter, the catheter comprising: a catheter shaft having a proximal insertion end portion and a distal end portion, a drainage member associated with the distal end portion of the catheter shaft; and a water capture element associated with the drainage member wherein the water capture element is configured to extend radially outward in a direction from a longitudinal axis of the catheter shaft, such that the water capture element receives a force of flushing water impinging thereon so as to propel the catheter down the toilet.
A planning device for tumour targeting ablation planning, comprising; - a processing unit; - an interface unit; and - a display unit; wherein the interface unit is configured to provide at least one segmented tumour in a 3D data set to be treated in an ablation procedure; and to provide a predetermined ablation profile; wherein the processing unit is configured to generate a contour of the segmented tumour; to overlap the predetermined ablation profile with at least a part of the at least one segmented tumour; said processing unit being characterized in that it is configured to identify an overlapping region; to apply a predetermined safety factor at least to a part of the overlapping region to generate a modified overlapping region; and to determine parts of the overlapping region that are arranged outside the modified overlapping region as critical overlapping portions; and wherein the display unit is configured to display the contour of the segmented tumour; to display the predetermined ablation profile overlapped with at least a part of the at least one segmented tumour; and to display the critical overlapping portions in relation with the contour and the ablation profile as virtual planning ablation result. - a processing unit; - an interface unit; and - a display unit;
A cellulase variant derived from a parent cellulase having an amino acid sequence that is at least 90% identical to SEQ ID NO:3, wherein the variant is a mature form having cellulase activity and comprising a substitution at one to ten positions, wherein the one to ten positions include at least position 5, and wherein the positions are numbered by correspondence with the amino acid sequence of a reference cellobiohydrolase II set forth as SEQ ID NO:3, and wherein said substitution at position 5 is selected from the group consisting of: S5A, S5D, S5F, S5I, S5L, S5N and S5P, and wherein said cellulase variant has improved expression, activity and/or stability in comparison to said reference CBH2.
A system comprising: a state analysis device comprising: index calculation means for calculating, based on a flow speed of fluid flowing out of piping, and a pressure of the fluid inside the piping at two or more locations of the piping, an index indicating a state of the piping, and determination means for determining the state of the piping based on the index, a pseudo leakage control unit connected to the state analysis device for controlling a flow rate of the fluid flowing out of the piping; and pressure detection units connected to the state analysis device for detecting the pressure of the fluid inside the piping during a period when the flow rate of the fluid flowing out of the piping changes, wherein the index calculation means is configured to control the pseudo leakage control unit to artificially reproduce fluid leakage from the piping, and calculate the index indicating the state of the piping, based on the pressure detected by the pressure detection units when the flow rate of the fluid flowing out of the piping changes. a state analysis device comprising: index calculation means for calculating, based on a flow speed of fluid flowing out of piping, and a pressure of the fluid inside the piping at two or more locations of the piping, an index indicating a state of the piping, and determination means for determining the state of the piping based on the index, index calculation means for calculating, based on a flow speed of fluid flowing out of piping, and a pressure of the fluid inside the piping at two or more locations of the piping, an index indicating a state of the piping, and determination means for determining the state of the piping based on the index, a pseudo leakage control unit connected to the state analysis device for controlling a flow rate of the fluid flowing out of the piping; and pressure detection units connected to the state analysis device for detecting the pressure of the fluid inside the piping during a period when the flow rate of the fluid flowing out of the piping changes, wherein the index calculation means is configured to control the pseudo leakage control unit to artificially reproduce fluid leakage from the piping, and calculate the index indicating the state of the piping, based on the pressure detected by the pressure detection units when the flow rate of the fluid flowing out of the piping changes.
A cylinder bore wall thermal insulator (36a, 36b, 36c) configured to be set in a groove-like cooling water channel of a cylinder block of an internal combustion engine including cylinder bores (12a1, 12a2, 12b1, 12b2) and for insulating bore walls in a one-side half among the bore walls of all the cylinder bores (12a1, 12a2, 12b1, 12b2) or a part of the bore walls on one side among the bore walls of all the cylinder bores (12a1, 12a2, 12b1, 12b2), the thermal insulator (36a, 36b, 36c) comprising: a plurality of bore wall insulating sections (35, 35c) each having a shape of a single arc when viewed from above and for insulating a wall surface on the cylinder bore side of the groove-like cooling water channel; and a single supporting section (34a, 34b, 34c) having a shape conforming to a shape of the groove-like cooling water channel in a setting position of the thermal insulator (36a, 36b, 36c), the bore wall insulating sections (35, 35c) being fixed to the supporting section (34a, 34b, 34c), wherein the supporting section (34a, 34b, 34c) is provided on a rear surface side of the bore wall insulating sections (35, 35c), characterized in that the bore wall insulating sections (35, 35c) include: rubber members (31, 31c) configured to be brought into contact with the wall surface on the cylinder bore side of the groove-like cooling water channel and for covering the wall surface on the cylinder bore side of the groove-like cooling water channel; rear surface pressing members (32, 47) provided on rear surface sides of the rubber members (31, 31c) and for pressing the entire rubber members (31, 31c) toward the wall surface on the cylinder bore side of the groove-like cooling water channel from the rear side; and elastic members that are configured to urge the rear surface pressing members (34, 47) to press the rubber members (31, 31c) toward the wall surface on the cylinder bore side of the groove-like cooling water channel, wherein the elastic members attached to the bore wall insulating sections (35, 35c) pass through a first opening formed on the supporting section (34a, 34b, 34c) and are configured to project toward a wall surface on the opposite side of the wall surface on the cylinder bore side of the groove-like cooling water channel, and only a center or a vicinity of the center in an arc direction of each of the bore wall insulating sections (35, 35c) is fixed to the supporting section (34a, 34b, 34c).
A method for identifying the presence or absence of a genetic mutation in a genomic region of interest comprising a target nucleotide sequence, comprising the steps of: a) providing a sample of cross-linked DNA; b) fragmenting the crosslinked DNA; c) ligating the fragmented crosslinked DNA; d) reversing the crosslinking; e) optionally fragmenting the DNA of step d), preferably with a restriction enzyme; f) optionally, ligating the fragmented DNA of step d) or e) to at least one adaptor; g) capturing the ligated DNA fragments of step d) or e) comprising the target nucleotide sequence using a capture probe to separate (amplified) ligated DNA fragments comprising the target nucleotide sequence from (amplified) ligated DNA fragments not comprising the target nucleotide sequence; optionally amplifying the ligated DNA fragments of step d) or e) comprising the target nucleotide sequence using at least one primer which hybridises to the target nucleotide sequence before or after the capture step, or amplifying the ligated DNA fragments of step f) using at least one oligonucleotide primer which hybridises to the target nucleotide sequence and at least one oligonucleotide primer which hybridises to the at least one adaptor before or after the capture step; h) determining at least part of the sequence of the (amplified) ligated DNA fragments of step g) comprising the target nucleotide sequence using high throughput sequencing; i) aligning the determined sequences of the (amplified) ligated DNA fragments to a reference sequence; j) identifying the presence or absence of a genetic mutation in the determined sequences. a) providing a sample of cross-linked DNA; b) fragmenting the crosslinked DNA; c) ligating the fragmented crosslinked DNA; d) reversing the crosslinking; e) optionally fragmenting the DNA of step d), preferably with a restriction enzyme; f) optionally, ligating the fragmented DNA of step d) or e) to at least one adaptor; g) capturing the ligated DNA fragments of step d) or e) comprising the target nucleotide sequence using a capture probe to separate (amplified) ligated DNA fragments comprising the target nucleotide sequence from (amplified) ligated DNA fragments not comprising the target nucleotide sequence; optionally amplifying the ligated DNA fragments of step d) or e) comprising the target nucleotide sequence using at least one primer which hybridises to the target nucleotide sequence before or after the capture step, or amplifying the ligated DNA fragments of step f) using at least one oligonucleotide primer which hybridises to the target nucleotide sequence and at least one oligonucleotide primer which hybridises to the at least one adaptor before or after the capture step; h) determining at least part of the sequence of the (amplified) ligated DNA fragments of step g) comprising the target nucleotide sequence using high throughput sequencing; i) aligning the determined sequences of the (amplified) ligated DNA fragments to a reference sequence; j) identifying the presence or absence of a genetic mutation in the determined sequences.
A system, comprising: a light projecting subsystem configured to project a pattern of structured light; a time-of-flight, ToF, sensor configured to detect reflections of the projected pattern of structured light off of a surface, and provide one or more time-of-flight indications associated with one or more portions of the pattern of structured light; and a processing engine electrically coupled with a non-transitory computer readable medium having machine readable instructions stored thereon, which, when executed by the processing engine, cause the system to: determine one or more depth measures associated with one or more portions of the surface based on the one or more time-of-flight indications associated with the pattern of structured light; and wherein the light projecting subsystem comprises a switchable diffuser, and the light projecting subsystem is configured to project flood light when the switchable diffuser is in a first state and project structured light when the switchable diffuser is in a second state, characterized in that the switchable diffuser comprises a MSLC type of liquid crystal. a light projecting subsystem configured to project a pattern of structured light; a time-of-flight, ToF, sensor configured to detect reflections of the projected pattern of structured light off of a surface, and provide one or more time-of-flight indications associated with one or more portions of the pattern of structured light; and a processing engine electrically coupled with a non-transitory computer readable medium having machine readable instructions stored thereon, which, when executed by the processing engine, cause the system to: determine one or more depth measures associated with one or more portions of the surface based on the one or more time-of-flight indications associated with the pattern of structured light; and wherein the light projecting subsystem comprises a switchable diffuser, and the light projecting subsystem is configured to project flood light when the switchable diffuser is in a first state and project structured light when the switchable diffuser is in a second state, characterized in that the switchable diffuser comprises a MSLC type of liquid crystal. determine one or more depth measures associated with one or more portions of the surface based on the one or more time-of-flight indications associated with the pattern of structured light; and wherein the light projecting subsystem comprises a switchable diffuser, and the light projecting subsystem is configured to project flood light when the switchable diffuser is in a first state and project structured light when the switchable diffuser is in a second state, characterized in that the switchable diffuser comprises a MSLC type of liquid crystal.
A method comprising: setting a power load in a network powered device and storing a representation of the power load in a non-volatile memory; incrementally increasing the power drawn by the power load one or more times until the power load meets one or more criteria, wherein the criteria include removal of power to the network powered device and reaching of a threshold power level; and storing an updated representation of the power load in the non-volatile memory for each increment wherein the representation of the power load corresponds to the amount of power available to the powered device. setting a power load in a network powered device and storing a representation of the power load in a non-volatile memory; incrementally increasing the power drawn by the power load one or more times until the power load meets one or more criteria, wherein the criteria include removal of power to the network powered device and reaching of a threshold power level; and storing an updated representation of the power load in the non-volatile memory for each increment wherein the representation of the power load corresponds to the amount of power available to the powered device.
An inkjet ink composition comprising: C.I. Pigment Yellow 180; a fatty acid amide compound; and a high molecular weight dispersant having a weight average molecular weight of 2,000 to 300,000, as measured by the GPC utilizing the equipment and the conditions as described in the description, wherein the fatty acid amide compound is a compound represented by the following formula, in the formula, R B represents a saturated or unsaturated aliphatic group having 5 to 30 carbon atoms, and a value of W B /W A is 0.05 to 0.2 in a case where the content of the C.I. Pigment Yellow 180 is set to W A and the content of the fatty acid amide compound is set to W B, in the ink composition. C.I. Pigment Yellow 180; a fatty acid amide compound; and a high molecular weight dispersant having a weight average molecular weight of 2,000 to 300,000, as measured by the GPC utilizing the equipment and the conditions as described in the description, wherein the fatty acid amide compound is a compound represented by the following formula, in the formula, R B represents a saturated or unsaturated aliphatic group having 5 to 30 carbon atoms, and a value of W B /W A is 0.05 to 0.2 in a case where the content of the C.I. Pigment Yellow 180 is set to W A and the content of the fatty acid amide compound is set to W B, in the ink composition.
A catheter comprising: an elongated, flexible tubular catheter body having proximal and distal ends and a lumen extending therethrough; a deflectable intermediate section at the distal end of the catheter body, the intermediate section comprising a flexible integrated tubing construction having at least one pair of diametrically-opposed lumens defining a first plane; a tip section at a distal end of the intermediate section; a control handle at the proximal end of the catheter body; first and second puller wires, each extending through a different lumen of the diametrically - opposed lumens of the intermediate section and through the lumen of the catheter body, each puller wire having a proximal end anchored to the control handle and a distal end anchored at a location at or near the distal end of the intermediate section, whereby the first and second puller wires are longitudinally moveable relative to the catheter body to cause deflection of the intermediate section, and two elongated bias members, each extending along the intermediate section, the two bias members defining a second plane perpendicular to the first plane, wherein the bias members, bias the intermediate section to maintain the perpendicular relationship between the first and second planes when deflected by the puller wires, characterised in that the integrated construction comprises an inner layer, a braided mesh and an outer layer, wherein the bias members are situated between the inner layer and the braided mesh. an elongated, flexible tubular catheter body having proximal and distal ends and a lumen extending therethrough; a deflectable intermediate section at the distal end of the catheter body, the intermediate section comprising a flexible integrated tubing construction having at least one pair of diametrically-opposed lumens defining a first plane; a tip section at a distal end of the intermediate section; a control handle at the proximal end of the catheter body; first and second puller wires, each extending through a different lumen of the diametrically - opposed lumens of the intermediate section and through the lumen of the catheter body, each puller wire having a proximal end anchored to the control handle and a distal end anchored at a location at or near the distal end of the intermediate section, whereby the first and second puller wires are longitudinally moveable relative to the catheter body to cause deflection of the intermediate section, and two elongated bias members, each extending along the intermediate section, the two bias members defining a second plane perpendicular to the first plane, wherein the bias members, bias the intermediate section to maintain the perpendicular relationship between the first and second planes when deflected by the puller wires, characterised in that the integrated construction comprises an inner layer, a braided mesh and an outer layer, wherein the bias members are situated between the inner layer and the braided mesh.
A vehicle lighting device including at least one light source arranged so as to emit light, a printed circuit board on which the light source is mounted, at least one lens arranged to receive the light emitted by said light source and to project a light beam towards a glass plate of the device, and a means for attaching the lens to the printed circuit board, characterized in that said attachment means is a thermally conductive clip arranged to present a thermal link between the printed circuit board and the lens so as to conduct heat emitted by the printed circuit board towards a space between the lens and the glass plate.
A cutting assembly for a surgical instrument having a drive assembly, said cutting assembly comprising: a tube assembly comprising a longitudinal axis defined between a distal end opposite a proximal end, and a cutting window near said distal end and adapted to be applied to a surgical site of a patient with said cutting window comprising a distal boundary opposite a proximal boundary, said tube assembly further comprising: an outer tube comprising an outer cutting window near said distal end of said tube assembly; and an inner tube coaxially disposed within and rotatable relative to said outer tube with the drive assembly, said inner tube comprising an inner cutting window near said distal end and a lumen extending between said proximal end and said inner cutting window with said inner cutting window and said outer cutting window defining said cutting window of said tube assembly; characterized in that the tube assembly still further comprises: a projection within said lumen of said inner tube with at least a portion of said projection positioned distal to said proximal boundary of said cutting window, said projection providing a reduced cross sectional area to said lumen of said inner tube relative to a cross sectional area of said lumen proximal to said projection with said reduced cross sectional area adapted to reduce the size of material removable through said cutting window to reduce clogging of said tube assembly. an outer tube comprising an outer cutting window near said distal end of said tube assembly; and an inner tube coaxially disposed within and rotatable relative to said outer tube with the drive assembly, said inner tube comprising an inner cutting window near said distal end and a lumen extending between said proximal end and said inner cutting window with said inner cutting window and said outer cutting window defining said cutting window of said tube assembly;