A dry powder inhaler with a distal end and a proximal end, the dry powder inhaler comprising: at least one inlet and at least one outlet, wherein a communication between said at least one inlet and said at least one outlet at least comprises a mixing and deaggregation chamber and at least two dosage communications between the at least one inlet and the chamber, wherein the at least one outlet is arranged at a first end of the dry powder drug inhaler, while the at least one inlet is arranged at a zone in an opposite second end of the dry powder inhaler, wherein the first end is the proximal end and the opposite, second end is the distal end; a first medicament reservoir for housing a dry powder first medicament; a second medicament reservoir for housing a dry powder second medicament; a dosage mechanism (104, 108) for arranging at least one dose of a medicament between the at least one inlet and the chamber, such that said at least one dose may be delivered upon inhalation at said at least one outlet through said communications; wherein the dosage mechanism (104, 108) is configured to withdraw an inhaler metered dose of the dry powder in the first and second medicament reservoirs (109, 110) in a dose collecting position from the reservoirs (109, 110) into said dosage communications in a dose administering position; wherein the dosage mechanism (104, 108) comprises a dose disc with at least one opening per reservoir (109, 110), wherein the dose disc may be rotated between the dose collecting position, wherein the openings are positioned in the reservoirs (109, 110), and the dose administering position, wherein the openings communicate with said dosage communications; wherein said dosage communications have directions when entering the chamber for allowing jet streams through communications to interact, such that medicament in said jet streams can interact to deaggregate; characterised in that said dosage communications have intersecting directions when entering the chamber. at least one inlet and at least one outlet, wherein a communication between said at least one inlet and said at least one outlet at least comprises a mixing and deaggregation chamber and at least two dosage communications between the at least one inlet and the chamber, wherein the at least one outlet is arranged at a first end of the dry powder drug inhaler, while the at least one inlet is arranged at a zone in an opposite second end of the dry powder inhaler, wherein the first end is the proximal end and the opposite, second end is the distal end; a first medicament reservoir for housing a dry powder first medicament; a second medicament reservoir for housing a dry powder second medicament; a dosage mechanism (104, 108) for arranging at least one dose of a medicament between the at least one inlet and the chamber, such that said at least one dose may be delivered upon inhalation at said at least one outlet through said communications; wherein the dosage mechanism (104, 108) is configured to withdraw an inhaler metered dose of the dry powder in the first and second medicament reservoirs (109, 110) in a dose collecting position from the reservoirs (109, 110) into said dosage communications in a dose administering position; wherein the dosage mechanism (104, 108) comprises a dose disc with at least one opening per reservoir (109, 110), wherein the dose disc may be rotated between the dose collecting position, wherein the openings are positioned in the reservoirs (109, 110), and the dose administering position, wherein the openings communicate with said dosage communications; wherein said dosage communications have directions when entering the chamber for allowing jet streams through communications to interact, such that medicament in said jet streams can interact to deaggregate; characterised in that said dosage communications have intersecting directions when entering the chamber.