A compound of formula I wherein R1 is a 5-10 membered aromatic ring having 0-4 ring heteroatoms each independently selected from the group consisting of nitrogen, oxygen, and sulfur, wherein each substitutable ring carbon is independently substituted by -Rc; R2 is selected from the group consisting of -NCH 2 C(NH 2)RdRd' where Rd and Rd' are each independently branched or unbranched -(C 1 -C 6)alkyl, wherein x is 1-3 and y is 1-2, or R2 is wherein Rb' is or and wherein: L' is a linker selected from the group consisting of a bond, a substituted or unsubstituted -(C 1 -C 6)alkyl- which may be branched or unbranched, and wherein Ring L is a 5-7 membered cyclic or aromatic ring and m and m' are independently 0-3; Ra' is H or branched or unbranched -(C 1 -C 6)alkyl; Rc and Rc' are each independently selected from the group consisting of H, halo, trihalomethyl, trihalomethoxy, branched or unbranched -(C 1 -C 6)alkyl, phenyl, branched or unbranched -(C 1 -C 6)alkyl-OR, -C(=O)R, -CO 2 R, -S 2 R, -OR, NO 2, -CN, -NH 2, NRR', - NHC(=O)R, -NHC =O, -C NRR', -S n R, and -SO 2 NRR' (wherein NRR' can form a 4 to 6 member ring), wherein n is 0, 1, or 2; and R and R' are each independently H, branched or unbranched -(C 1 -C 6)alkyl, branched or unbranched -(C 1 -C 6)alkyl alcohol, or -CO 2 -(C 1 -C 6)alkyl; wherein where nitrogen is present as a heteroatom, it is at least 2 carbon atoms from any nitrogen atom attached to the triazine ring, and wherein the ring carbons next to a ring nitrogen are not substituted with -OR, -NO 2, - NH 2, -NRR', -NHC R, -NHC OR, -S n R, or -SO 2 NRR'; or a pharmaceutically acceptable salt thereof. R1 is a 5-10 membered aromatic ring having 0-4 ring heteroatoms each independently selected from the group consisting of nitrogen, oxygen, and sulfur, wherein each substitutable ring carbon is independently substituted by -Rc; R2 is selected from the group consisting of -NCH 2 C(NH 2)RdRd' where Rd and Rd' are each independently branched or unbranched -(C 1 -C 6)alkyl, wherein x is 1-3 and y is 1-2, or R2 is wherein Rb' is or and wherein: L' is a linker selected from the group consisting of a bond, a substituted or unsubstituted -(C 1 -C 6)alkyl- which may be branched or unbranched, and wherein Ring L is a 5-7 membered cyclic or aromatic ring and m and m' are independently 0-3; Ra' is H or branched or unbranched -(C 1 -C 6)alkyl; Rc and Rc' are each independently selected from the group consisting of H, halo, trihalomethyl, trihalomethoxy, branched or unbranched -(C 1 -C 6)alkyl, phenyl, branched or unbranched -(C 1 -C 6)alkyl-OR, -C(=O)R, -CO 2 R, -S 2 R, -OR, NO 2, -CN, -NH 2, NRR', - NHC(=O)R, -NHC =O, -C NRR', -S n R, and -SO 2 NRR' (wherein NRR' can form a 4 to 6 member ring), wherein n is 0, 1, or 2; and R and R' are each independently H, branched or unbranched -(C 1 -C 6)alkyl, branched or unbranched -(C 1 -C 6)alkyl alcohol, or -CO 2 -(C 1 -C 6)alkyl; wherein where nitrogen is present as a heteroatom, it is at least 2 carbon atoms from any nitrogen atom attached to the triazine ring, and wherein the ring carbons next to a ring nitrogen are not substituted with -OR, -NO 2, - NH 2, -NRR', -NHC R, -NHC OR, -S n R, or -SO 2 NRR'; or a pharmaceutically acceptable salt thereof. L' is a linker selected from the group consisting of a bond, a substituted or unsubstituted -(C 1 -C 6)alkyl- which may be branched or unbranched, and wherein Ring L is a 5-7 membered cyclic or aromatic ring and m and m' are independently 0-3; Ra' is H or branched or unbranched -(C 1 -C 6)alkyl; Rc and Rc' are each independently selected from the group consisting of H, halo, trihalomethyl, trihalomethoxy, branched or unbranched -(C 1 -C 6)alkyl, phenyl, branched or unbranched -(C 1 -C 6)alkyl-OR, -C(=O)R, -CO 2 R, -S 2 R, -OR, NO 2, -CN, -NH 2, NRR', - NHC(=O)R, -NHC =O, -C NRR', -S n R, and -SO 2 NRR' (wherein NRR' can form a 4 to 6 member ring), wherein n is 0, 1, or 2; and R and R' are each independently H, branched or unbranched -(C 1 -C 6)alkyl, branched or unbranched -(C 1 -C 6)alkyl alcohol, or -CO 2 -(C 1 -C 6)alkyl; wherein where nitrogen is present as a heteroatom, it is at least 2 carbon atoms from any nitrogen atom attached to the triazine ring, and wherein the ring carbons next to a ring nitrogen are not substituted with -OR, -NO 2, - NH 2, -NRR', -NHC R, -NHC OR, -S n R, or -SO 2 NRR'; or a pharmaceutically acceptable salt thereof.