An open-cavity, reduced-pressure treatment system for providing reduced-pressure treatment within a body cavity of a patient, the open-cavity, reduced-pressure treatment system comprising: a treatment device comprising: a plurality of encapsulated leg members, each encapsulated leg member having an interior portion with a leg manifold member positioned therein, the encapsulated leg members including fenestrations to allow fluid flow between an outer surface of the encapsulated leg members and the interior portion, and a central connection member, wherein the central connection member has a connection manifold member and wherein the leg manifold members are in fluid communication with the connection manifold member, the central connection member having a first side and a second, inward-facing side; a manifold for disposing proximate the first side of the central connection member, the first side of the central connection member and the manifold being operable to distribute reduced pressure to the central connection member; a sealing member for disposing on a portion of a patient's epidermis and operable to form a pneumatic seal over the body cavity; a reduced-pressure delivery conduit; a reduced-pressure source for producing reduced pressure, the reduced-pressure source fluidly coupled to the reduced-pressure delivery conduit; and a reduced-pressure interface for coupling to the sealing member and operable to fluidly couple the reduced-pressure delivery conduit to the manifold. a treatment device comprising: a plurality of encapsulated leg members, each encapsulated leg member having an interior portion with a leg manifold member positioned therein, the encapsulated leg members including fenestrations to allow fluid flow between an outer surface of the encapsulated leg members and the interior portion, and a central connection member, wherein the central connection member has a connection manifold member and wherein the leg manifold members are in fluid communication with the connection manifold member, the central connection member having a first side and a second, inward-facing side; a plurality of encapsulated leg members, each encapsulated leg member having an interior portion with a leg manifold member positioned therein, the encapsulated leg members including fenestrations to allow fluid flow between an outer surface of the encapsulated leg members and the interior portion, and a central connection member, wherein the central connection member has a connection manifold member and wherein the leg manifold members are in fluid communication with the connection manifold member, the central connection member having a first side and a second, inward-facing side; a manifold for disposing proximate the first side of the central connection member, the first side of the central connection member and the manifold being operable to distribute reduced pressure to the central connection member; a sealing member for disposing on a portion of a patient's epidermis and operable to form a pneumatic seal over the body cavity; a reduced-pressure delivery conduit; a reduced-pressure source for producing reduced pressure, the reduced-pressure source fluidly coupled to the reduced-pressure delivery conduit; and a reduced-pressure interface for coupling to the sealing member and operable to fluidly couple the reduced-pressure delivery conduit to the manifold.