A neurostimulation system, comprising: an implantable medical device, IMD, comprising: an electrode assembly; a neurostimulator coupled to the electrode assembly, wherein the neurostimulator is adapted to deliver a stimulation signal to a patient; an electrocardiogram sensor (1104, 1114); and a control system (1102, 1112) programmed to: monitor the ECG of the patient using the ECG sensor to determine a baseline for the patient, wherein the baseline comprises one or more of a baseline T-wave alternans, a baseline heart rate turbulence slope, and a baseline heart rate turbulence onset; and characterized in that the control system is further programmed to: either a) activate the IMD to deliver to the patient a plurality of stimulation signals at increasing stimulation intensities until a target threshold is detected, wherein the target threshold comprises one or more of a target T-wave alternans threshold, a target heart rate turbulence slope threshold, and a target heart rate turbulence onset threshold and activate the IMD to deliver a therapeutic level of stimulation corresponding to the stimulation intensity at which the target threshold was detected; or b) activate the IMD to deliver to the patient a plurality of stimulation signals at increasing stimulation intensities until a target change from the baseline is observed; and identify a neural fulcrum zone corresponding to the stimulation intensity during which the target change from the baseline was observed. an electrode assembly; a neurostimulator coupled to the electrode assembly, wherein the neurostimulator is adapted to deliver a stimulation signal to a patient; an electrocardiogram sensor (1104, 1114); and a control system (1102, 1112) programmed to: monitor the ECG of the patient using the ECG sensor to determine a baseline for the patient, wherein the baseline comprises one or more of a baseline T-wave alternans, a baseline heart rate turbulence slope, and a baseline heart rate turbulence onset; and characterized in that the control system is further programmed to: either a) activate the IMD to deliver to the patient a plurality of stimulation signals at increasing stimulation intensities until a target threshold is detected, wherein the target threshold comprises one or more of a target T-wave alternans threshold, a target heart rate turbulence slope threshold, and a target heart rate turbulence onset threshold and activate the IMD to deliver a therapeutic level of stimulation corresponding to the stimulation intensity at which the target threshold was detected; or b) activate the IMD to deliver to the patient a plurality of stimulation signals at increasing stimulation intensities until a target change from the baseline is observed; and identify a neural fulcrum zone corresponding to the stimulation intensity during which the target change from the baseline was observed. monitor the ECG of the patient using the ECG sensor to determine a baseline for the patient, wherein the baseline comprises one or more of a baseline T-wave alternans, a baseline heart rate turbulence slope, and a baseline heart rate turbulence onset; and characterized in that the control system is further programmed to: either a) activate the IMD to deliver to the patient a plurality of stimulation signals at increasing stimulation intensities until a target threshold is detected, wherein the target threshold comprises one or more of a target T-wave alternans threshold, a target heart rate turbulence slope threshold, and a target heart rate turbulence onset threshold and activate the IMD to deliver a therapeutic level of stimulation corresponding to the stimulation intensity at which the target threshold was detected; or b) activate the IMD to deliver to the patient a plurality of stimulation signals at increasing stimulation intensities until a target change from the baseline is observed; and identify a neural fulcrum zone corresponding to the stimulation intensity during which the target change from the baseline was observed. either a) activate the IMD to deliver to the patient a plurality of stimulation signals at increasing stimulation intensities until a target threshold is detected, wherein the target threshold comprises one or more of a target T-wave alternans threshold, a target heart rate turbulence slope threshold, and a target heart rate turbulence onset threshold and activate the IMD to deliver a therapeutic level of stimulation corresponding to the stimulation intensity at which the target threshold was detected; or b) activate the IMD to deliver to the patient a plurality of stimulation signals at increasing stimulation intensities until a target change from the baseline is observed; and identify a neural fulcrum zone corresponding to the stimulation intensity during which the target change from the baseline was observed.