A process for preparing a compound of Formula III: which comprises: contacting a lactone of Formula II: with an azacycloalkylamine of formula II-Am: followed by contact with a sulfonyl halide of formula II-Su: R 4 -SO 2 W (II-Su) in the presence of tertiary amine base to obtain a compound of Formula III wherein: P G1 is a first amine protecting group which forms with the amino nitrogen to which it is attached a carbamate, a benzylamine, or a sulfonamide; P G2 is a second amine protecting group selected from (i) carbamates and (ii) benzylamines; k is an integer equal to 0, 1, or 2; R 2 and R 3 are defined as follows: (a) R 2 is H, C 1-6 alkyl, -O-C 1-6 alkyl, -O-Si(-C 1-6 alkyl) 3, or -O-Si(-C 1-6 alkyl)(-phenyl) 2, and each R 3 is H or C 1-6 alkyl; or (b) alternatively and with the proviso that k is 1 or 2, R 2 and the R 3 adjacent to R 2 together with the carbon atoms to which each is attached form C 5-7 cycloalkyl which is optionally substituted with from 1 to 3 substituents each of which is independently C 1-6 alkyl, -O-C 1-6 alkyl, -O-Si(-C 1-6 alkyl) 3, or -O-Si(-C 1-6 alkyl) (-phenyl) 2; and any other R 3 is H or C 1-6 alkyl; R 4 is phenyl optionally substituted with from 1 to 3 substituents each of which is independently C 1-4 alkyl, C 1-4 haloalkyl, -O-C 1-4 alkyl, -O-C 1-4 haloalkyl, Cl, Br, F, or NO 2; C 1-4 alkyl; or C 1-4 haloalkyl; R 5 is H or C 1-3 alkyl; R 6 and R 8 are independently H, C 1-3 alkyl, O-C 1-3 alkyl, or N(-C 1-3 alkyl) 2; each R 7 and R 9 is independently H or C 1-6 alkyl W is halogen; p is 0, 1, or 2; q is 0, 1, or 2; and p + q = 0, 1, 2, or 3. contacting a lactone of Formula II: P G1 is a first amine protecting group which forms with the amino nitrogen to which it is attached a carbamate, a benzylamine, or a sulfonamide; P G2 is a second amine protecting group selected from (i) carbamates and (ii) benzylamines; k is an integer equal to 0, 1, or 2; R 2 and R 3 are defined as follows: (a) R 2 is H, C 1-6 alkyl, -O-C 1-6 alkyl, -O-Si(-C 1-6 alkyl) 3, or -O-Si(-C 1-6 alkyl)(-phenyl) 2, and each R 3 is H or C 1-6 alkyl; or (b) alternatively and with the proviso that k is 1 or 2, R 2 and the R 3 adjacent to R 2 together with the carbon atoms to which each is attached form C 5-7 cycloalkyl which is optionally substituted with from 1 to 3 substituents each of which is independently C 1-6 alkyl, -O-C 1-6 alkyl, -O-Si(-C 1-6 alkyl) 3, or -O-Si(-C 1-6 alkyl) (-phenyl) 2; and any other R 3 is H or C 1-6 alkyl; (a) R 2 is H, C 1-6 alkyl, -O-C 1-6 alkyl, -O-Si(-C 1-6 alkyl) 3, or -O-Si(-C 1-6 alkyl)(-phenyl) 2, and each R 3 is H or C 1-6 alkyl; or (b) alternatively and with the proviso that k is 1 or 2, R 2 and the R 3 adjacent to R 2 together with the carbon atoms to which each is attached form C 5-7 cycloalkyl which is optionally substituted with from 1 to 3 substituents each of which is independently C 1-6 alkyl, -O-C 1-6 alkyl, -O-Si(-C 1-6 alkyl) 3, or -O-Si(-C 1-6 alkyl) (-phenyl) 2; and any other R 3 is H or C 1-6 alkyl; R 4 is phenyl optionally substituted with from 1 to 3 substituents each of which is independently C 1-4 alkyl, C 1-4 haloalkyl, -O-C 1-4 alkyl, -O-C 1-4 haloalkyl, Cl, Br, F, or NO 2; C 1-4 alkyl; or C 1-4 haloalkyl; phenyl optionally substituted with from 1 to 3 substituents each of which is independently C 1-4 alkyl, C 1-4 haloalkyl, -O-C 1-4 alkyl, -O-C 1-4 haloalkyl, Cl, Br, F, or NO 2; C 1-4 alkyl; or C 1-4 haloalkyl; R 5 is H or C 1-3 alkyl; R 6 and R 8 are independently H, C 1-3 alkyl, O-C 1-3 alkyl, or N(-C 1-3 alkyl) 2; each R 7 and R 9 is independently H or C 1-6 alkyl W is halogen; p is 0, 1, or 2; q is 0, 1, or 2; and p + q = 0, 1, 2, or 3.