mhurhangee/ep-ind-claims huggingface dataset:
A liquid varnish composition, suitable for application on a hard surface in the oral cavity, said varnish composition comprising: a) a drug for the treatment of a head and neck cancer or for the prevention of the development of pre-malignant lesions to said cancer, wherein said drug is selected from the group consisting of rapamycin, everolimus, temsirolimus, biolimus A9, ABT578, and AP2357 3; b) at least one non-degradable hydrophobic film-forming polymer, wherein said polymer is ethyl cellulose; and c) a pharmaceutically acceptable volatile carrier; wherein said volatile carrier is ethyl alcohol, or a mixture of ethyl alcohol and water. a) a drug for the treatment of a head and neck cancer or for the prevention of the development of pre-malignant lesions to said cancer, wherein said drug is selected from the group consisting of rapamycin, everolimus, temsirolimus, biolimus A9, ABT578, and AP2357 3; b) at least one non-degradable hydrophobic film-forming polymer, wherein said polymer is ethyl cellulose; and c) a pharmaceutically acceptable volatile carrier; wherein said volatile carrier is ethyl alcohol, or a mixture of ethyl alcohol and water.
A process for the preparation of -2-[ -2-oxo-4-propyl-pyrrolidin-1-yl] butanamide (brivaracetam) having the formula, comprising: (a) reacting -2-[ -2-oxo-4-propyl-pyrrolidin-1-yl] butyric acid methyl ester having the formula II, with protease from Bacillus licheniformis defined as EC 3.4.21.62 in an aqueous solution; (b) extracting the reaction mixture with an organic solvent selected from the group consisting of n-hexanes, n-heptanes, and diisopropyl ether, to remove the unreacted, and acidifying the aqueous layer using 5N hydrochloric acid; (c) extracting the acidified layer from step (b), with an organic solvent selected from the group consisting of dichloromethane, ethyl acetate, and isopropyl acetate, to obtain -2- [ -2-oxo-4-propyl-pyrrolidin-1-yl] butyric acid of the formula, having >95% chiral purity; and (d) reacting the compound of formula with ammonia in dichloromethane, at a temperature of -10° C to -20° C, in the presence of ethyl chloroformate and a base such as triethyl amine or N-methyl morpholine, to obtain Brivaracetam. (a) reacting -2-[ -2-oxo-4-propyl-pyrrolidin-1-yl] butyric acid methyl ester having the formula II, with protease from Bacillus licheniformis defined as EC 3.4.21.62 in an aqueous solution; (b) extracting the reaction mixture with an organic solvent selected from the group consisting of n-hexanes, n-heptanes, and diisopropyl ether, to remove the unreacted, and acidifying the aqueous layer using 5N hydrochloric acid; (c) extracting the acidified layer from step (b), with an organic solvent selected from the group consisting of dichloromethane, ethyl acetate, and isopropyl acetate, to obtain -2- [ -2-oxo-4-propyl-pyrrolidin-1-yl] butyric acid of the formula, having >95% chiral purity; and (d) reacting the compound of formula with ammonia in dichloromethane, at a temperature of -10° C to -20° C, in the presence of ethyl chloroformate and a base such as triethyl amine or N-methyl morpholine, to obtain Brivaracetam.
A temperature sensor including a temperature sensitive device which is configured to be disposed in a flow path through which fluid flows and whose electric characteristic changes as a function of temperature of the fluid in the flow path, signal lines connected at top end sides thereof to said temperature sensitive device through electrode wires and at base end sides thereof to lead wires for connection with an external circuit, a sheath member retaining the signal lines therein, and a holding member which holds an outer circumferential surface of said sheath member directly or indirectly through another member, characterized in that a protruding length L1 that is a distance between an inner circumference of said flow path and a top end of the temperature sensor on an axis of the temperature sensor and a held length L2 that is a distance between a top end of a portion of said sheath member which is held by the holding member directly or indirectly and the top end of the temperature sensor have a relation of L1 < L2; if a diameter of a portion of the protruding length L1 which holds said temperature sensitive device is defined as a sensor outer diameter D, the sensor outer diameter D is 3.2mm or less, and the held length L2 is 75mm or more; and the protruding length L1 and the held length L2 are so adjusted that a resonance frequency of the top end of the temperature sensor against acceleration in a radius direction of the temperature sensor is 480Hz or less as measured using a laser Doppler oscillometer.
Magnetic trigger with an adjustable trigger function for a switching device with a movably supported anchor, a spring which exerts a force on the anchor, and a first and a second permanent magnet (18, 19), the magnetic fields of which have opposite polarities, characterised by an electrical coil, which in connection with energisation dependent on a trigger function produces a magnetic field acting on the anchor, which either moves the anchor into the trigger position or holds the anchor in an locked position against the pressure of the spring and an adjusting device for setting the total magnetic field, produced through superposition of the magnetic fields of the first and the second permanent magnet, to a first or a second strength, wherein the total magnetic field with the first strength is dimensioned so as to hold the anchor in the locked position against the force of the spring, and the total magnetic field of the second strength is dimensioned so that by itself it is not sufficient to hold the anchor in the locked position against the force of the spring.
An excess voltage circuit breaker with a rotational disc and an electronic assembly of a component to improve operation reliability, wherein the electronic 1. An excess voltage circuit breaker with a rotational disc and an electronic assembly of the component comprises a resistor with positive thermal coefficient that is connected in parallel with a a GDT gas circuit breaker that consists in gas circuit breakers (2b and 2c); that the common point of exit of the resistor and the GDT gas circuit breaker is via thermal member, which is simultaneously a first connection electrode arranged on a varistor body; that the electronic assembly of the component functions in a way that in case of rapid transitional events a branch with the GDT gas circuit breaker is operable, and in case of sporadically increased voltages the branch via resistor is operable; that the resistor with positive thermal coefficient is configured to limit the current through the varistor, when the impressed voltage on connection terminals exceeds the voltage threshold of the varistor; that the varistor is configured to shift to a low ohmic state, which allows that high current runs via the varistor and thus enables the functioning of external over-current protection; characterized in that a shift of the first connection electrode triggers a rotating the movement of the rotational disc. 1. An excess voltage circuit breaker with a rotational disc and an electronic assembly of the component comprises a resistor with positive thermal coefficient that is connected in parallel with a a GDT gas circuit breaker that consists in gas circuit breakers (2b and 2c); that the common point of exit of the resistor and the GDT gas circuit breaker is via thermal member, which is simultaneously a first connection electrode arranged on a varistor body; that the electronic assembly of the component functions in a way that in case of rapid transitional events a branch with the GDT gas circuit breaker is operable, and in case of sporadically increased voltages the branch via resistor is operable; that the resistor with positive thermal coefficient is configured to limit the current through the varistor, when the impressed voltage on connection terminals exceeds the voltage threshold of the varistor; that the varistor is configured to shift to a low ohmic state, which allows that high current runs via the varistor and thus enables the functioning of external over-current protection; characterized in that a shift of the first connection electrode triggers a rotating the movement of the rotational disc.
A data transmission method, comprising: receiving to-be-transmitted data currently transmitted from a data source node; determining an average receiving interval and an average transmitting interval based on a historical data receiving interval and a historical data transmitting interval; determining a splitting transmission number based on the average receiving interval and the average transmitting interval; obtaining a plurality of data fragments based on a data size of the to-be-transmitted data and the splitting transmission number; and sequentially and uniformly transmitting the data fragments to a next-level node within a subsequent period with a duration being the average receiving interval. receiving to-be-transmitted data currently transmitted from a data source node; determining an average receiving interval and an average transmitting interval based on a historical data receiving interval and a historical data transmitting interval; determining a splitting transmission number based on the average receiving interval and the average transmitting interval; obtaining a plurality of data fragments based on a data size of the to-be-transmitted data and the splitting transmission number; and sequentially and uniformly transmitting the data fragments to a next-level node within a subsequent period with a duration being the average receiving interval.
A method of controlling the operation of a fuel injector said fuel injector including a valve actuated by an actuator actuated by a solenoid, said actuator being operated by applying an activation pulse profile to said solenoid, comprising: a) measuring the voltage across the solenoid during a time period of the valve closing phase, subsequent to a valve opening phase; b) summing said voltage over said time period c) controlling and varying the activation pulse profile during a subsequent activation cycle of said fuel injector based on sum from step b). a) measuring the voltage across the solenoid during a time period of the valve closing phase, subsequent to a valve opening phase; b) summing said voltage over said time period c) controlling and varying the activation pulse profile during a subsequent activation cycle of said fuel injector based on sum from step b).
An auto-tensioner comprising: a stationary member having a first cylindrical portion; a rotatable member which has a second cylindrical portion of which at least a part is disposed to overlap the first cylindrical portion in a radial direction, and is supported rotatably relative to the stationary member; a coil spring which is accommodated on insides of the first cylindrical portion and the second cylindrical portion and has one end locked to the stationary member and the other end locked to the rotatable member; and a drainage mechanism provided at a boundary part of the first cylindrical portion and the second cylindrical portion, wherein the drainage mechanism comprises a water inlet configured by a gap between an outer peripheral surface of the first cylindrical portion and an outer peripheral surface of the second cylindrical portion and being open along a peripheral direction, a water passage which is configured by a gap between a water collecting groove formed along the peripheral direction in the outer peripheral surface of one of the two cylindrical portions and the other cylindrical portion, and communicates with the water inlet, and characterised by at least one drainage port configured by a cutout formed in a peripheral wall on an outside in the radial direction of the water passage. a stationary member having a first cylindrical portion; a rotatable member which has a second cylindrical portion of which at least a part is disposed to overlap the first cylindrical portion in a radial direction, and is supported rotatably relative to the stationary member; a coil spring which is accommodated on insides of the first cylindrical portion and the second cylindrical portion and has one end locked to the stationary member and the other end locked to the rotatable member; and a drainage mechanism provided at a boundary part of the first cylindrical portion and the second cylindrical portion, wherein the drainage mechanism comprises a water inlet configured by a gap between an outer peripheral surface of the first cylindrical portion and an outer peripheral surface of the second cylindrical portion and being open along a peripheral direction, a water passage which is configured by a gap between a water collecting groove formed along the peripheral direction in the outer peripheral surface of one of the two cylindrical portions and the other cylindrical portion, and communicates with the water inlet, and characterised by at least one drainage port configured by a cutout formed in a peripheral wall on an outside in the radial direction of the water passage.
A hardware-based processing node (605, 610, 705, 710, 1005, 1010, 2200) of an object memory fabric (405, 600, 700, 3305), the hardware-based processing node comprising: a processor; and a memory module (625, 630) comprising a hardware component installed in the hardware-based processing node for storing and managing one or more memory objects within an object-based memory space (500, 805), characterized in that: each memory object is arranged to be created natively within the memory module, each memory object is arranged to be accessed through an object namespace using a single memory reference instruction, without Input/Output, I/O, instructions, each memory object is arranged to be managed by the memory module through the object namespace at a single memory layer, without distinction between volatile memory and non-volatile storage, and the memory module is arranged to provide an interface layer (3310, 3315, 3320, 3325, 3330, 3335, 3340, 3345) below an application layer (3350, 3355, 3360, 3365) of a software stack, the interface layer comprising one or more storage managers (3325, 3330, 3335, 3340, 3345) arranged to manage hardware of the processor and to control at a hardware layer portions of the object-based memory space visible to a virtual address space and physical address space of the processor. a processor; and a memory module (625, 630) comprising a hardware component installed in the hardware-based processing node for storing and managing one or more memory objects within an object-based memory space (500, 805), each memory object is arranged to be created natively within the memory module, each memory object is arranged to be accessed through an object namespace using a single memory reference instruction, without Input/Output, I/O, instructions, each memory object is arranged to be managed by the memory module through the object namespace at a single memory layer, without distinction between volatile memory and non-volatile storage, and the memory module is arranged to provide an interface layer (3310, 3315, 3320, 3325, 3330, 3335, 3340, 3345) below an application layer (3350, 3355, 3360, 3365) of a software stack, the interface layer comprising one or more storage managers (3325, 3330, 3335, 3340, 3345) arranged to manage hardware of the processor and to control at a hardware layer portions of the object-based memory space visible to a virtual address space and physical address space of the processor.
Process for producing sodium alkoxide of the formula RONa and potassium alkoxide of the formula ROK, wherein (a) ROH is reacted with NaOH in countercurrent, whereby RONa and a vapour B 1 comprising water and ROH are obtained, (b) ROH is reacted with KOH in countercurrent, whereby ROK and a vapour B 2 comprising water and ROH are obtained, wherein R is a C 1 -C 6 -hydrocarbon radical, characterized in that the reactions according to (a) and (b) proceed simultaneously and spatially separated, and that the vapours B 1 and B 2 are at least partially mixed to give the mixed vapour B M comprising ROH and water, and that ROH is at least partially separated off from B M by distillation. (a) ROH is reacted with NaOH in countercurrent, whereby RONa and a vapour B 1 comprising water and ROH are obtained, (b) ROH is reacted with KOH in countercurrent, whereby ROK and a vapour B 2 comprising water and ROH are obtained, wherein R is a C 1 -C 6 -hydrocarbon radical, that the reactions according to (a) and (b) proceed simultaneously and spatially separated, and that the vapours B 1 and B 2 are at least partially mixed to give the mixed vapour B M comprising ROH and water, and that ROH is at least partially separated off from B M by distillation.
A retaining cap for a plasma arc torch comprising: a shell having an exterior surface that defines, at least in part, a first liquid coolant channel; the retaining cap being characterized in that it further comprises a liner circumferentially disposed within the shell and having an interior surface that defines, at least in part, a second liquid coolant channel; and a gas flow channel defined at least in part by and locatedbetween the shell and the liner. a shell having an exterior surface that defines, at least in part, a first liquid coolant channel; the retaining cap being characterized in that it further comprises a liner circumferentially disposed within the shell and having an interior surface that defines, at least in part, a second liquid coolant channel; and a gas flow channel defined at least in part by and locatedbetween the shell and the liner.
Intravenous formulation that comprises inositol phosphate and/or any of the salts thereof for use in maintaining or increasing the levels of inositol phosphate and/or any of the salts thereof in the plasma of a person subjected to dialysis.
A washing control method for a dishwasher, the dishwasher having a motor to drive a circulation pump for circulating wash water through a circulation hose (28a, 28b) from a dishwasher compartment towards one or more spray arms (26a, 26b, 26c) of the dishwasher, the washing control method comprising: - detecting, by a flow meter, a flow rate of the wash water in the circulation hose of the dishwasher while washing is performed using the wash water; and - determining, by a control unit, a washing operation based on the detected flow rate of the wash water, wherein determining, by the control unit, the washing operation based on the detected flow rate of the wash water comprises: - determining a motor speed corresponding to the flow rate detected by the flow meter; - comparing the detected flow rate to a predetermined threshold reference flow rate for the wash water corresponding to the motor speed so determined, and - selecting one of a first washing operation of the dishwasher if the detected flow rate of the wash water does not exceed the predetermined threshold reference flow rate and a second washing operation of the dishwasher if the detected flow rate of the wash water exceeds the predetermined threshold reference flow rate, characterized by - draining of the wash water if the first washing operation of the dishwasher is selected, and - continuing washing using the wash water if the second washing operation of the dishwasher is selected. - detecting, by a flow meter, a flow rate of the wash water in the circulation hose of the dishwasher while washing is performed using the wash water; and - determining, by a control unit, a washing operation based on the detected flow rate of the wash water, - determining a motor speed corresponding to the flow rate detected by the flow meter; - comparing the detected flow rate to a predetermined threshold reference flow rate for the wash water corresponding to the motor speed so determined, and - selecting one of a first washing operation of the dishwasher if the detected flow rate of the wash water does not exceed the predetermined threshold reference flow rate and a second washing operation of the dishwasher if the detected flow rate of the wash water exceeds the predetermined threshold reference flow rate, characterized by - draining of the wash water if the first washing operation of the dishwasher is selected, and - continuing washing using the wash water if the second washing operation of the dishwasher is selected.
An electronic device, comprising: a first sensor configured to obtain an electromagnetic, 'EM', signal from an external device; a first communication module configured to provide a magnetic stripe transmission, 'MST', signal; a processor; and a memory coupled with the processor, wherein the memory is configured to store a waveform table including a plurality of unique EM signals corresponding to a plurality of external devices, and instructions which, upon execution, instruct the processor to: compare the EM signal with each of the unique signals from the plurality of unique EM signals included in the waveform table, thereby identifying the corresponding external device; and control the first communication module to transmit, to the external device, the MST signal which is of a predetermined type specified for the identified external device. a first sensor configured to obtain an electromagnetic, 'EM', signal from an external device; a first communication module configured to provide a magnetic stripe transmission, 'MST', signal; a processor; and a memory coupled with the processor, wherein the memory is configured to store a waveform table including a plurality of unique EM signals corresponding to a plurality of external devices, and instructions which, upon execution, instruct the processor to: compare the EM signal with each of the unique signals from the plurality of unique EM signals included in the waveform table, thereby identifying the corresponding external device; and control the first communication module to transmit, to the external device, the MST signal which is of a predetermined type specified for the identified external device. compare the EM signal with each of the unique signals from the plurality of unique EM signals included in the waveform table, thereby identifying the corresponding external device; and control the first communication module to transmit, to the external device, the MST signal which is of a predetermined type specified for the identified external device.