mhurhangee/ep-ind-claims huggingface dataset:
An in vitro method of classifying a pediatric patient with septic shock as high risk or low risk of adverse outcome, the method comprising: analyzing a sample from a pediatric patient with septic shock to determine the expression levels of two or more biomarkers selected from the group consisting of JAK2, LYN, PRKCB, and SOS2; determining whether the expression levels of the two or more biomarkers are elevated above a cut-off level; and classifying the patient as endotype A / high risk or other than endotype A / high risk, wherein a classification of endotype A / high risk comprises: a) a non-elevated level of JAK2 and a non-elevated level of PRKCB; or b) a non-elevated level of JAK2, an elevated level of PRKCB, and a non-elevated level of LYN; and wherein a classification other than endotype A / high risk comprises: c) a non-elevated level of JAK2, an elevated level of PRKCB, and an elevated level of LYN; or d) an elevated level of JAK2, a non-elevated level of SOS2, and a highly elevated level of LYN; or e) elevated levels of JAK2 and SOS2; or f) an elevated level of JAK2, a non-elevated level of SOS2, and a non-highly elevated level of LYN. analyzing a sample from a pediatric patient with septic shock to determine the expression levels of two or more biomarkers selected from the group consisting of JAK2, LYN, PRKCB, and SOS2; determining whether the expression levels of the two or more biomarkers are elevated above a cut-off level; and classifying the patient as endotype A / high risk or other than endotype A / high risk, wherein a classification of endotype A / high risk comprises: a) a non-elevated level of JAK2 and a non-elevated level of PRKCB; or b) a non-elevated level of JAK2, an elevated level of PRKCB, and a non-elevated level of LYN; a) a non-elevated level of JAK2 and a non-elevated level of PRKCB; or b) a non-elevated level of JAK2, an elevated level of PRKCB, and a non-elevated level of LYN; and wherein a classification other than endotype A / high risk comprises: c) a non-elevated level of JAK2, an elevated level of PRKCB, and an elevated level of LYN; or d) an elevated level of JAK2, a non-elevated level of SOS2, and a highly elevated level of LYN; or e) elevated levels of JAK2 and SOS2; or f) an elevated level of JAK2, a non-elevated level of SOS2, and a non-highly elevated level of LYN. c) a non-elevated level of JAK2, an elevated level of PRKCB, and an elevated level of LYN; or d) an elevated level of JAK2, a non-elevated level of SOS2, and a highly elevated level of LYN; or e) elevated levels of JAK2 and SOS2; or f) an elevated level of JAK2, a non-elevated level of SOS2, and a non-highly elevated level of LYN.
A heat pump comprising: an outdoor unit which houses in a package: a compressor: a receiver; a subcooler provided in a liquid refrigerant path of a refrigerant flow downstream of the receiver; an accumulator provided in an intake path of the compressor; and an oil separator provided in a discharge path of the compressor, wherein: the subcooler comprises a plate type heat exchanger, each of the oil separator and the subcooler located on a straight line P1 is adjacent to each of the accumulator and the receiver located on a straight line P2 in the planar view, wherein the straight line P1 intersects with the straight line P2 between the accumulator and the receiver. an outdoor unit which houses in a package: a compressor: a receiver; a subcooler provided in a liquid refrigerant path of a refrigerant flow downstream of the receiver; an accumulator provided in an intake path of the compressor; and an oil separator provided in a discharge path of the compressor, a receiver; a subcooler provided in a liquid refrigerant path of a refrigerant flow downstream of the receiver; an accumulator provided in an intake path of the compressor; and an oil separator provided in a discharge path of the compressor, wherein: the subcooler comprises a plate type heat exchanger, each of the oil separator and the subcooler located on a straight line P1 is adjacent to each of the accumulator and the receiver located on a straight line P2 in the planar view, wherein the straight line P1 intersects with the straight line P2 between the accumulator and the receiver. the subcooler comprises a plate type heat exchanger, each of the oil separator and the subcooler located on a straight line P1 is adjacent to each of the accumulator and the receiver located on a straight line P2 in the planar view, wherein the straight line P1 intersects with the straight line P2 between the accumulator and the receiver.
A semiconductor device comprising: a voltage monitor that is supplied by a second power supply voltage (SVCC) different from a first power supply voltage supplied to a circuit to be monitored, the voltage monitor being configured to monitor the first power supply voltage; and a delay monitor that is supplied by the first power supply voltage, the delay monitor being configured to monitor the signal propagation period of time of a critical path in the circuit to be monitored, wherein the voltage monitor is configured to compare the first power supply voltage with a predetermined reference voltage (VREF) and output a first reset signal (VRST) when the first power supply voltage is equal to or lower than the reference voltage (VREF), wherein the delay monitor is configured to output a second reset signal (DRST) when the signal propagation period of time of the critical path in the circuit to be monitored becomes equal to or longer than a predetermined period of time, and wherein the semiconductor device further comprises means (13, 14) configured to generate a reset signal to initialise the circuit to be monitored when the first reset signal (VRST) and the second reset signal (DRST) are transferred to the circuit to be monitored. a voltage monitor that is supplied by a second power supply voltage (SVCC) different from a first power supply voltage supplied to a circuit to be monitored, the voltage monitor being configured to monitor the first power supply voltage; and a delay monitor that is supplied by the first power supply voltage, the delay monitor being configured to monitor the signal propagation period of time of a critical path in the circuit to be monitored, wherein the voltage monitor is configured to compare the first power supply voltage with a predetermined reference voltage (VREF) and output a first reset signal (VRST) when the first power supply voltage is equal to or lower than the reference voltage (VREF), wherein the delay monitor is configured to output a second reset signal (DRST) when the signal propagation period of time of the critical path in the circuit to be monitored becomes equal to or longer than a predetermined period of time, and wherein the semiconductor device further comprises means (13, 14) configured to generate a reset signal to initialise the circuit to be monitored when the first reset signal (VRST) and the second reset signal (DRST) are transferred to the circuit to be monitored.
Feedthrough insulator comprising: - a central rod of connection which extends along a longitudinal axis, - a sleeve positioned coaxially around said rod of connection with a respective circular shell radially spaced (D-21) with respect to the central rod, - a sensor of electric field and/or of magnetic field, positioned in proximity of the inner surface of said shell of the sleeve, - a carrying body formed by dielectric material that contains and embeds said central rod, said sleeve and said sensor, characterized by the fact it further comprises at least one screen element (161, 162; 261, 262; 361, 362) which is positioned near at least one of two openings (23sx, 23dx) configurated at the opposite longitudinal ends of the sleeve, said screen element (161, 162; 261, 262; 361, 362) being positioned at a determined longitudinal distance (D-161, D-162; D-261, D-262; R-363, R-364) with respect to the respective longitudinal end (24sx, 24dx) of the sleeve, wherein at least one screen element (161, 162; 261, 262; 361, 362) is able to screen the entry of the harmful-undesired electrical field lines generated by surrounding conductors so that said harmful-undesired electrical field lines do not sink-close on said sensor. - a central rod of connection which extends along a longitudinal axis, - a sleeve positioned coaxially around said rod of connection with a respective circular shell radially spaced (D-21) with respect to the central rod, - a sensor of electric field and/or of magnetic field, positioned in proximity of the inner surface of said shell of the sleeve, - a carrying body formed by dielectric material that contains and embeds said central rod, said sleeve and said sensor,
An emulsion suitable for ocular, nasal or otic administration comprising water, a buffering agent, an oil, an emulsifier, a pH adjuster, a multifunctional synthetic compound of formula I, wherein: x is 1 to 3 or mixtures thereof; x+y is equal to 3; a is 0 to 2; z is equal to x; B is O- or OM; A is an anion; M is a cation; Y is selected from the group consisting of OH, O-C 1 -C 10 alkyl and O-C 1 -C 10 alkenyl; and R1, R2 and R3 are the same or different and are alkyl, substituted alkyl, alkyl aryl or alkenyl groups, optionally interrupted by -NHC(=O)-, of up to 16 carbon atoms with the proviso that the total carbon atoms in R1+R2+R3 is between 10 and 24, and optionally a therapeutic agent, wherein the amount of the compound of formula I is from 0.05 to 0.2%. a buffering agent, an oil, an emulsifier, a pH adjuster, a multifunctional synthetic compound of formula I, x is 1 to 3 or mixtures thereof; x+y is equal to 3; a is 0 to 2; z is equal to x; B is O- or OM; A is an anion; M is a cation; Y is selected from the group consisting of OH, O-C 1 -C 10 alkyl and O-C 1 -C 10 alkenyl; R1, R2 and R3 are the same or different and are alkyl, substituted alkyl, alkyl aryl or alkenyl groups, optionally interrupted by -NHC(=O)-, of up to 16 carbon atoms with the proviso that the total carbon atoms in R1+R2+R3 is between 10 and 24,
A chemical-mechanical polishing composition comprising: (a) abrasive particles, (b) a cobalt accelerator selected from a compound having the formula: NR 1 R 2 R 3 wherein R 1, R 2, and R 3 are independently selected from hydrogen, carboxyalkyl, substituted carboxyalkyl, hydroxyalkyl, substituted hydroxyalkyl and aminocarbonylalkyl, wherein none or one of R 1, R 2, and R 3 are hydrogen; dicarboxyheterocycles; heterocyclylalkyl-α-amino acids; N-(amidoalkyl)amino acids; unsubstituted heterocycles; alkyl-substituted heterocycles; substituted-alkyl-substituted heterocycles; N-aminoalkyl-α-amino acids; and combinations thereof, (c) a cobalt corrosion inhibitor, (d) an oxidizing agent that oxidizes cobalt, and (e) water, wherein the polishing composition has a pH of about 3 to about 8.5. (a) abrasive particles, (b) a cobalt accelerator selected from a compound having the formula: NR 1 R 2 R 3 wherein R 1, R 2, and R 3 are independently selected from hydrogen, carboxyalkyl, substituted carboxyalkyl, hydroxyalkyl, substituted hydroxyalkyl and aminocarbonylalkyl, wherein none or one of R 1, R 2, and R 3 are hydrogen; dicarboxyheterocycles; heterocyclylalkyl-α-amino acids; N-(amidoalkyl)amino acids; unsubstituted heterocycles; alkyl-substituted heterocycles; substituted-alkyl-substituted heterocycles; N-aminoalkyl-α-amino acids; and combinations thereof, (c) a cobalt corrosion inhibitor, (d) an oxidizing agent that oxidizes cobalt, and (e) water,
A method for monitoring a position and/or a displacement of a display element generated on a display screen by a video game console coupled to a game controller comprising a control lever arranged to be moved in at least two degrees of freedom in an area delimited by a user, the method comprising the steps consisting of: - measuring a position of the control lever in the determined area with at least one sensor outputting at least one electrical signal per degree of freedom, - projecting into a base plane the position of the control lever measured with said at least one sensor, to determine a first set of coordinates, - determining a circle of positions (Cp), centered on a rest position of the control lever and passing through the position of the control lever projected into the base plane, - determining a square (Ccp) circumscribed to the circle of positions (Cp), - projecting onto the circumscribed square (Ccp) at least one coordinate of the first set of coordinates, - calculating a second set of coordinates in a Cartesian coordinate system, based on the projection of said at least one coordinate of the first set of coordinates onto the circumscribed square (Ccp), so as to be able to send to the console the second set of Cartesian coordinates which is an image of the first set of coordinates. - measuring a position of the control lever in the determined area with at least one sensor outputting at least one electrical signal per degree of freedom, - projecting into a base plane the position of the control lever measured with said at least one sensor, to determine a first set of coordinates, - determining a circle of positions (Cp), centered on a rest position of the control lever and passing through the position of the control lever projected into the base plane, - determining a square (Ccp) circumscribed to the circle of positions (Cp), - projecting onto the circumscribed square (Ccp) at least one coordinate of the first set of coordinates, - calculating a second set of coordinates in a Cartesian coordinate system, based on the projection of said at least one coordinate of the first set of coordinates onto the circumscribed square (Ccp), so as to be able to send to the console the second set of Cartesian coordinates which is an image of the first set of coordinates.
A collection fitting for sampling fluid from a tissue site, the collection fitting comprising: a switch fitting having a first passage and a second passage; a bypass switch coupled to the switch fitting and operable in a bypass position to fluidly couple the first passage and the second passage through the bypass switch, and in response to movement of the bypass switch, operable in a sampling position to fluidly couple the first passage and the second passage through a specimen container; a cavity formed in an end of the switch fitting, the first passage and the second passage opening into the cavity and extending through the switch fitting; a cap coupled to the end of the switch fitting and having a portion disposed within the cavity; a first bore in the cap fluidly coupled to the first passage; a second bore in the cap fluidly coupled to the second passage, wherein each bore (914, 916) extends through the cap; and a gap formed between an end of the cap and an inner wall of the cavity, the gap comprising a sensing bypass to fluidly communicate pressure between the first bore and the second bore when the bypass switch is both in the bypass position and in the sampling position. a switch fitting having a first passage and a second passage; a bypass switch coupled to the switch fitting and operable in a bypass position to fluidly couple the first passage and the second passage through the bypass switch, and in response to movement of the bypass switch, operable in a sampling position to fluidly couple the first passage and the second passage through a specimen container; a cavity formed in an end of the switch fitting, the first passage and the second passage opening into the cavity and extending through the switch fitting; a cap coupled to the end of the switch fitting and having a portion disposed within the cavity; a first bore in the cap fluidly coupled to the first passage; a second bore in the cap fluidly coupled to the second passage, wherein each bore (914, 916) extends through the cap; and a gap formed between an end of the cap and an inner wall of the cavity, the gap comprising a sensing bypass to fluidly communicate pressure between the first bore and the second bore when the bypass switch is both in the bypass position and in the sampling position.
Method for aligning a filling machine, in particular for the production of sausages characterized by the following steps: a) measuring the height (a, b) and/or the inclination of a filling machine according to an actual state, b) transmitting the measured values (s) to a calculation unit, c) comparing the actual state of the height and/or the inclination with a target state of the height and/or the inclination by the calculation unit, and d) adjusting the height (a, b) and/or the inclination on the basis of said comparison in step c). a) measuring the height (a, b) and/or the inclination of a filling machine according to an actual state, b) transmitting the measured values (s) to a calculation unit, c) comparing the actual state of the height and/or the inclination with a target state of the height and/or the inclination by the calculation unit, and d) adjusting the height (a, b) and/or the inclination on the basis of said comparison in step c).
A transformed mammalian cell comprising: - A heterologous nucleic acid sequence (i) encoding a polypeptide consisting of the sequence SEQ ID NO: 35, and - optionally, at least one heterologous nucleic acid sequence (ii) encoding a therapeutic protein, the sequence of which therapeutic protein comprises at least one glycosylation site, said transformed mammalian cell expressing the therapeutic protein with a sialylation on said at least one glycosylation site. - A heterologous nucleic acid sequence (i) encoding a polypeptide consisting of the sequence SEQ ID NO: 35, and - optionally, at least one heterologous nucleic acid sequence (ii) encoding a therapeutic protein, the sequence of which therapeutic protein comprises at least one glycosylation site, said transformed mammalian cell expressing the therapeutic protein with a sialylation on said at least one glycosylation site.
Method for replacing a valve connected to a well head, wherein the valve is a chemical injection valve connected to the well head via an injection line housing, where an end of an injection line is provided within the injection line housing, where the method comprises the steps of: - connecting an injection line plugging tool to the chemical injection valve; - providing threads in the end of the injection line by means of the injection line plugging tool; - connecting an injection line plug to the threads of the injection line by means of the injection line plugging tool; - disconnecting the chemical injection valve from the injection line housing; - connecting a further chemical injection valve to the injection line housing; - connecting the injection line plugging tool to the further chemical injection valve; - removing the injection line plug from the end of the injection line by means of the injection line plugging tool; - disconnecting the injection line plugging tool from the further chemical injection valve. - connecting an injection line plugging tool to the chemical injection valve; - providing threads in the end of the injection line by means of the injection line plugging tool; - connecting an injection line plug to the threads of the injection line by means of the injection line plugging tool; - disconnecting the chemical injection valve from the injection line housing; - connecting a further chemical injection valve to the injection line housing; - connecting the injection line plugging tool to the further chemical injection valve; - removing the injection line plug from the end of the injection line by means of the injection line plugging tool; - disconnecting the injection line plugging tool from the further chemical injection valve.
A block storage arrangement having multiple container stacking compartments, a loading compartment arranged below the container stacking compartments, at least one loading vehicle (5, 5a) which is movable in the loading compartment and with which containers (3, 3a) can be stored from below in a container stacking compartment and can be removed from below from the container stacking compartment, and which has an electric drive assembly and an electrically rechargeable battery, and at least one transfer station, characterized in that an electrical charging device for the battery is arranged in the transfer station.
A diagnostic device for determining the presence of a target analyte in a fluid sample, comprising: a first fluid source; at least one covered channel; and fluid control means, configured to transfer a specific volume of fluid from the first fluid source to the or each covered channel, wherein the first fluid source is provided in the form of a preparation chamber (5, 105); characterized by a microfluid device which comprises the first fluid source, the at least one covered channel and the fluid control means, wherein the at least one covered channel (31, 131) is provided in the form of a microchannel, wherein the or each microchannel comprises a fluid inlet (37, 137) and a fluid outlet and a capture surface for selective capture of the target analyte; the microfluidic device further comprises a second fluid source, wherein the fluid control means is also configured to form a conduit between the second fluid source and the or each covered channel; and the microfluidic device further comprises a waste sump in fluid communication with the or each channel. a first fluid source; at least one covered channel; and fluid control means, configured to transfer a specific volume of fluid from the first fluid source to the or each covered channel, wherein the first fluid source is provided in the form of a preparation chamber (5, 105); characterized by a microfluid device which comprises the first fluid source, the at least one covered channel and the fluid control means, wherein the at least one covered channel (31, 131) is provided in the form of a microchannel, wherein the or each microchannel comprises a fluid inlet (37, 137) and a fluid outlet and a capture surface for selective capture of the target analyte; the microfluidic device further comprises a second fluid source, wherein the fluid control means is also configured to form a conduit between the second fluid source and the or each covered channel; and the microfluidic device further comprises a waste sump in fluid communication with the or each channel.
A comfort layer (16; 60; 66; 120) configured to overlay a core of a bedding or seating product (10; 70), said comfort layer (16; 60; 66; 120) comprising: a matrix of interconnected mini pocketed springs (28, 30; 300), each mini coil spring (28, 30; 300) being contained within a pocket (44, 45; 84), said pocket (44, 45; 84) having a weld seam (32; 80) around the pocket joining first and second pieces of fabric (22, 24; 74, 76) of the pocket, each weld seam (32; 80) having multiple weld segments (26; 78); said comfort layer (16; 60; 66; 120) having a center section (50; 122; 150) and a perimeter section (52; 126; 152), characterized in that said perimeter section (52; 126; 152) of said comfort layer (16; 60; 66; 120) surrounds the center section; and the mini pocketed springs (30; 300) within the pockets of the perimeter section (52; 126; 152) are made of thicker wire than the wire from which the mini pocketed springs within the pockets of the center section (50; 122; 150). a matrix of interconnected mini pocketed springs (28, 30; 300), each mini coil spring (28, 30; 300) being contained within a pocket (44, 45; 84), said pocket (44, 45; 84) having a weld seam (32; 80) around the pocket joining first and second pieces of fabric (22, 24; 74, 76) of the pocket, each weld seam (32; 80) having multiple weld segments (26; 78); said comfort layer (16; 60; 66; 120) having a center section (50; 122; 150) and a perimeter section (52; 126; 152), characterized in that said perimeter section (52; 126; 152) of said comfort layer (16; 60; 66; 120) surrounds the center section; and the mini pocketed springs (30; 300) within the pockets of the perimeter section (52; 126; 152) are made of thicker wire than the wire from which the mini pocketed springs within the pockets of the center section (50; 122; 150).