Method for throughput-optimized production of printed circuit boards on a pick-and-place line, wherein the printed circuit boards are divided into groups known as clusters, wherein each cluster is produced by means of a setup, wherein the setup is realized by means of changing tables that can be attached to the pick-and-place line, which changing tables each have at least one feed device for holding in readiness stocks of components, wherein a quantity of changing tables needed for each setup is designated as a changing table set and an empty changing table set comprises changing tables whose feed devices are empty, - wherein a setup is set up temporarily on empty changing table sets and after production of printed circuit boards is removed as a result of the picking and placing thereof, and - wherein one of the changing table sets can only be put into production when it has been completely set up in a pre-setup region and the changing table set can then only be set up again when the production performed with the changing table set has ended and the changing table set has been removed again in the pre-setup region, wherein the method comprises the following steps: a) recording a quantity of clusters, b) recording a number of empty changing table sets, c) recording the respective time duration for the creation of the setup for a cluster, d) recording the respective production time duration for the fabrication of a cluster on the pick-and-place line, e) selecting a setup sequence, in which the changing table sets are set up in the pre-setup region, with the aim of avoiding waiting times in production in which the same changing table sets are used for the production of printed circuit boards, f) optimizing the time sequence of the clusters taking into account the selected setup sequence so that the throughput on the pick-and-place line is maximized, g) carrying out the production of the printed circuit boards with the aid of the optimized time sequence of clusters, wherein furthermore the following steps are carried out: - recording one or more earliest possible time points for the beginning of the use of a changing table set, - recording an earliest possible time point for the beginning of production - recording an earliest possible time point for the beginning of setting up in the pre-setup region, and - optimizing the said sequence of clusters taking into account the recorded earliest time points. - wherein a setup is set up temporarily on empty changing table sets and after production of printed circuit boards is removed as a result of the picking and placing thereof, and - wherein one of the changing table sets can only be put into production when it has been completely set up in a pre-setup region and the changing table set can then only be set up again when the production performed with the changing table set has ended and the changing table set has been removed again in the pre-setup region, wherein the method comprises the following steps: a) recording a quantity of clusters, b) recording a number of empty changing table sets, c) recording the respective time duration for the creation of the setup for a cluster, d) recording the respective production time duration for the fabrication of a cluster on the pick-and-place line, e) selecting a setup sequence, in which the changing table sets are set up in the pre-setup region, with the aim of avoiding waiting times in production in which the same changing table sets are used for the production of printed circuit boards, f) optimizing the time sequence of the clusters taking into account the selected setup sequence so that the throughput on the pick-and-place line is maximized, g) carrying out the production of the printed circuit boards with the aid of the optimized time sequence of clusters, a) recording a quantity of clusters, b) recording a number of empty changing table sets, c) recording the respective time duration for the creation of the setup for a cluster, d) recording the respective production time duration for the fabrication of a cluster on the pick-and-place line, e) selecting a setup sequence, in which the changing table sets are set up in the pre-setup region, with the aim of avoiding waiting times in production in which the same changing table sets are used for the production of printed circuit boards, f) optimizing the time sequence of the clusters taking into account the selected setup sequence so that the throughput on the pick-and-place line is maximized, g) carrying out the production of the printed circuit boards with the aid of the optimized time sequence of clusters, - recording one or more earliest possible time points for the beginning of the use of a changing table set, - recording an earliest possible time point for the beginning of production - recording an earliest possible time point for the beginning of setting up in the pre-setup region, and - optimizing the said sequence of clusters taking into account the recorded earliest time points.