A tunable radio front end comprising: a first tunable impedance matching network; a second tunable impedance matching network; a transmission signal path comprising: a first tunable filter in communication with the first tunable impedance matching network, a first tunable power amplifier connected to the first tunable filter and tunable to roll off at a first desired frequency, and a radio transmitter connected to the first tunable power amplifier, characterized by each of the first tunable impedance matching network, the first tunable filter, and the first tunable power amplifier being adjustable to tuning settings at which the transmission signal path passes signals of a desired transmit frequency band and blocks signals of a desired receive frequency band; and a reception signal path comprising: a second tunable filter in communication with the second tunable impedance matching network, a first tunable low-noise amplifier connected to the second tunable filter and tunable to roll off at a second desired frequency, and a radio receiver connected to the first tunable low-noise amplifier, wherein each of the second tunable impedance matching network, the second tunable filter, and the first tunable low-noise amplifier are adjustable to tuning settings at which the reception signal path passes signals of the desired receive frequency band and blocks signals of the desired transmit frequency band. a first tunable impedance matching network; a second tunable impedance matching network; a transmission signal path comprising: a first tunable filter in communication with the first tunable impedance matching network, a first tunable power amplifier connected to the first tunable filter and tunable to roll off at a first desired frequency, and a radio transmitter connected to the first tunable power amplifier, characterized by each of the first tunable impedance matching network, the first tunable filter, and the first tunable power amplifier being adjustable to tuning settings at which the transmission signal path passes signals of a desired transmit frequency band and blocks signals of a desired receive frequency band; and a first tunable filter in communication with the first tunable impedance matching network, a first tunable power amplifier connected to the first tunable filter and tunable to roll off at a first desired frequency, and a radio transmitter connected to the first tunable power amplifier, characterized by each of the first tunable impedance matching network, the first tunable filter, and the first tunable power amplifier being adjustable to tuning settings at which the transmission signal path passes signals of a desired transmit frequency band and blocks signals of a desired receive frequency band; and a reception signal path comprising: a second tunable filter in communication with the second tunable impedance matching network, a first tunable low-noise amplifier connected to the second tunable filter and tunable to roll off at a second desired frequency, and a second tunable filter in communication with the second tunable impedance matching network, a first tunable low-noise amplifier connected to the second tunable filter and tunable to roll off at a second desired frequency, and a radio receiver connected to the first tunable low-noise amplifier, wherein each of the second tunable impedance matching network, the second tunable filter, and the first tunable low-noise amplifier are adjustable to tuning settings at which the reception signal path passes signals of the desired receive frequency band and blocks signals of the desired transmit frequency band.