mhurhangee/ep-ind-claims huggingface dataset:
An antibody or antibody fragment specific for a polypeptide comprising SEQ ID NO.: 1, or an orthologue thereof, wherein said antibody binds to an extracellular loop of MprF, and wherein said antibody or antibody fragment increases the susceptibility of a pathogen to a cationic antimicrobial peptide, wherein the loop consists of an amino acid sequence of ELSGINFKDTLVEFSKINR (SEQ ID NO.: 2), LGFKTLGVPEEKV (SEQ ID NO.: 5), DALYDGNHLT (SEQ ID NO.: 6) or DIYTIEMHTSVLR (SEQ ID NO.: 7), wherein said pathogen is a gram-positive bacterium and wherein said gram-positive bacterium is Staphylococcus aureus.
A turbine blade comprising: a platform; a blade body including cooling flow channels (25-31,42) including a meandering serpentine cooling flow channel; a fillet portion provided in a joint surface between the blade body and the platform; and a base portion including a supply cooling flow channel communicated with the cooling flow channels of the blade body, wherein the cooling flow channels include a bypass flow channel that is branched off from a high-pressure part of the cooling flow channels, is provided inside of the fillet portion so as to run along the fillet portion, and is connected to a low-pressure part of the cooling flow channels, and wherein the bypass flow channel has an entrance provided on an inner side in a radial direction from a portion of the fillet portion corresponding to the high-pressure part, and an exit provided on an outer side in the radial direction from a portion of the fillet portion corresponding to the low-pressure part. a platform; a blade body including cooling flow channels (25-31,42) including a meandering serpentine cooling flow channel; a fillet portion provided in a joint surface between the blade body and the platform; and a base portion including a supply cooling flow channel communicated with the cooling flow channels of the blade body, wherein the cooling flow channels include a bypass flow channel that is branched off from a high-pressure part of the cooling flow channels, is provided inside of the fillet portion so as to run along the fillet portion, and is connected to a low-pressure part of the cooling flow channels, and wherein the bypass flow channel has an entrance provided on an inner side in a radial direction from a portion of the fillet portion corresponding to the high-pressure part, and an exit provided on an outer side in the radial direction from a portion of the fillet portion corresponding to the low-pressure part.
A container (10, 20, 30, 40, 50, 60, 70, 80, 90, 161) for providing a medical solution, comprising: at least two compartments (A, B, C); an inlet connector (3, 33, 43, 51, 64, 73, 85) for connection to a lower compartment of said two compartments (A, B, C); a compartment divider (6, 21, 991, 992) separating said at least two compartments (A. B, C), characterized by an outlet connector (41, 51, 61, 71, 75, 81, 171) for connection to one of said at least two compartments (A,B,C); whereby said compartment divider (6, 21, 991, 992) is configured to controllably open when a pressure of liquid is applied through said inlet connector (3, 33, 43, 51, 64, 73, 85), and wherein at least one compartment (B, C), different from said lower compartment, comprises a powder. at least two compartments (A, B, C); an inlet connector (3, 33, 43, 51, 64, 73, 85) for connection to a lower compartment of said two compartments (A, B, C); a compartment divider (6, 21, 991, 992) separating said at least two compartments (A. B, C), characterized by an outlet connector (41, 51, 61, 71, 75, 81, 171) for connection to one of said at least two compartments (A,B,C); whereby said compartment divider (6, 21, 991, 992) is configured to controllably open when a pressure of liquid is applied through said inlet connector (3, 33, 43, 51, 64, 73, 85), and wherein at least one compartment (B, C), different from said lower compartment, comprises a powder.
Plasma spray nozzle, which, at one end in its inner channel, has a diverging part that has at least one powder injection hole (7, 7', 7", 7"'), characterized in that the at least one powder injection hole (7, 7', 7", 7"') is not arranged in the divergent region and in that the plasma spray nozzle has external cooling fins between the divergent part and the at least one hole (7, 7', 7", 7'").
A linearly scalable bioreactor system for use in carrying out a scalable biomanufacturing process, the system comprising: a bioprocessing bag having a flexible wall, a working volume of from about 2 liters to about 10 liters, and a height to diameter ratio at maximum working volume of about 1.5; an impeller mounted on an impeller plate attached to an inside bottom surface of the flexible wall, the ratio of the diameter of the impeller, Di, to the diameter of the bioprocessing bag, Dt, equal to a value of from about 0.6 to about 0.7; and a sparging surface positioned about 3-100 mm beneath the impeller. a bioprocessing bag having a flexible wall, a working volume of from about 2 liters to about 10 liters, and a height to diameter ratio at maximum working volume of about 1.5; an impeller mounted on an impeller plate attached to an inside bottom surface of the flexible wall, the ratio of the diameter of the impeller, Di, to the diameter of the bioprocessing bag, Dt, equal to a value of from about 0.6 to about 0.7; and a sparging surface positioned about 3-100 mm beneath the impeller.
Method for arc welding unalloyed or low-alloyed steels, wherein the entire alloying components amount to a maximum of 6% by weight of the low-alloyed steel, with a melting electrode under protective gas, in which the protective gas is a mixture comprising at least helium and an active gas as well as a further inert gas, wherein in dependence on the Si content of a welding wire used as the electrode, one of the following compositions of the protective gas is used, characterized in that if the welding wire is a normal electrode with a silicon content of 0.7 to 1.2%, the active gas fraction in the total volume of the protective gas is more than 0.5% to 1.5% and the helium fraction in the total volume of the protective gas is more than 30%, or if the welding wire has a low Si content of 0.05% to 0.1%, the active gas fraction in the total volume of the protective gas is 3% to 10%.
An in vitro or ex vivo method of altering a double stranded DNA target nucleic acid in a cell comprising introducing into the cell a first foreign nucleic acid encoding two or more guide RNAs with each guide RNA having a spacer sequence, a tracr mate sequence and a tracr sequence, and with a portion of the tracr sequence being hybridized to the tracr mate sequence and with the tracr mate sequence being linked by a linker nucleic acid sequence and with each spacer sequence being complementary to an adjacent site in the DNA target nucleic acid, introducing into the cell a second foreign nucleic acid encoding at least one Cas9 protein nickase having one inactive nuclease domain and being guided by the two or more guide RNAs, and wherein the two or more guide RNAs and the at least one Cas9 protein nickase are expressed and wherein the at least one Cas9 protein nickase co-localizes with two of the two or more RNAs to the DNA target nucleic acid and nicks the DNA target nucleic acid resulting in two adjacent nicks, wherein the two adjacent nicks are on different strands of the double stranded DNA and create a double stranded break. introducing into the cell a first foreign nucleic acid encoding two or more guide RNAs with each guide RNA having a spacer sequence, a tracr mate sequence and a tracr sequence, and with a portion of the tracr sequence being hybridized to the tracr mate sequence and with the tracr mate sequence being linked by a linker nucleic acid sequence and with each spacer sequence being complementary to an adjacent site in the DNA target nucleic acid, introducing into the cell a second foreign nucleic acid encoding at least one Cas9 protein nickase having one inactive nuclease domain and being guided by the two or more guide RNAs, and wherein the two or more guide RNAs and the at least one Cas9 protein nickase are expressed and wherein the at least one Cas9 protein nickase co-localizes with two of the two or more RNAs to the DNA target nucleic acid and nicks the DNA target nucleic acid resulting in two adjacent nicks, wherein the two adjacent nicks are on different strands of the double stranded DNA and create a double stranded break.
A system for introducing a fluid composition into Schlemm's canal, comprising: a housing; a cannula attached to the distal end of the housing and comprising a distal tip; a flexible elongate member comprising a lumen, a proximal end, and a distal end, wherein the distal end is slidable within the cannula between a retracted position and an extended position, wherein the distal end is within the cannula in the retracted position and distal to the distal tip of the cannula in the extended position; a fluid assembly comprising a reservoir and a plunger comprising a proximal end, a distal end, and a lumen, wherein the proximal end of the plunger is slidable within the reservoir, and wherein the reservoir comprises a fluid composition and is fluidly connected to the lumen of the flexible elongate member via the lumen of the plunger; a drive assembly configured to simultaneously move the flexible elongate member from the extended position to the retracted position and deliver the fluid composition from the reservoir through the lumen of the flexible elongate member, wherein the drive assembly comprises a linear gear relative to which the proximal end of the elongate member and the distal end of the plunger are fixed; and a linkage coupling the fluid assembly and the linear gear, wherein the linkage is attached via a one-way ratchet to the linear gear. a housing; a cannula attached to the distal end of the housing and comprising a distal tip; a flexible elongate member comprising a lumen, a proximal end, and a distal end, wherein the distal end is slidable within the cannula between a retracted position and an extended position, wherein the distal end is within the cannula in the retracted position and distal to the distal tip of the cannula in the extended position; a fluid assembly comprising a reservoir and a plunger comprising a proximal end, a distal end, and a lumen, wherein the proximal end of the plunger is slidable within the reservoir, and wherein the reservoir comprises a fluid composition and is fluidly connected to the lumen of the flexible elongate member via the lumen of the plunger; a drive assembly configured to simultaneously move the flexible elongate member from the extended position to the retracted position and deliver the fluid composition from the reservoir through the lumen of the flexible elongate member, wherein the drive assembly comprises a linear gear relative to which the proximal end of the elongate member and the distal end of the plunger are fixed; and a linkage coupling the fluid assembly and the linear gear, wherein the linkage is attached via a one-way ratchet to the linear gear.
A hub for a torsional vibration damper comprising: a main body comprising: a plate having a front face and a back face; an annular core extending axially outward from the back face of the plate and defining an innermost, outer radial surface and defining a first bore through the main body, an outermost, radial, elastomer-receiving surface spaced apart from the innermost outer radial surface by the plate; and a seal nose mated to the innermost, outer radial surface of the annular core and mechanically engaged with the main body for rotation together without a welded joint; characterized in that the main body comprises a first material and the seal nose comprises a second material, wherein the first material and the second material are different in that the first material is softer than the second material; wherein the innermost, outer radial surface of the main body includes threads, and the seal nose has threads threadingly engaged the threads of the innermost, outer radial surface of the main body, and a keyway formed within the first bore of the annular core for mating with a key on a crankshaft broaches the threads of the seal nose, thereby locking the threads of the annular core and the seal nose together. a main body comprising: a plate having a front face and a back face; an annular core extending axially outward from the back face of the plate and defining an innermost, outer radial surface and defining a first bore through the main body, an outermost, radial, elastomer-receiving surface spaced apart from the innermost outer radial surface by the plate; and a plate having a front face and a back face; an annular core extending axially outward from the back face of the plate and defining an innermost, outer radial surface and defining a first bore through the main body, an outermost, radial, elastomer-receiving surface spaced apart from the innermost outer radial surface by the plate; and a seal nose mated to the innermost, outer radial surface of the annular core and mechanically engaged with the main body for rotation together without a welded joint; characterized in that the main body comprises a first material and the seal nose comprises a second material, wherein the first material and the second material are different in that the first material is softer than the second material; wherein the innermost, outer radial surface of the main body includes threads, and the seal nose has threads threadingly engaged the threads of the innermost, outer radial surface of the main body, and a keyway formed within the first bore of the annular core for mating with a key on a crankshaft broaches the threads of the seal nose, thereby locking the threads of the annular core and the seal nose together.
Plant cultivation cabinet having a cabinet body and at least one cabinet door and a lighting system arranged in the cabinet body, characterised in that a light shield is arranged in the cabinet body between the lighting system and the at least one cabinet door, wherein the light shield is made of a material that is only partly transparent.
A method for network access in a mobile communication device which has a display, the method comprising the acts of: performing a scanning operation to identify a wireless communication network which is identified by a wireless network identifier; receiving, during the scanning operation, from the wireless communication network one or more hotspot aggregator identifiers, each said hotspot aggregator identifier identifying a hotspot aggregator made available via the identified wireless communication network; displaying on the display a user input prompt prompting the user for credentials for one of hotspot aggregators (150, 152) made available by the identified wireless communication network receiving the credentials for the one of the hotspot aggregators from the user; sending, via the wireless communication network, the received credentials to the hotspot aggregator server; and receiving a response from the hotspot aggregator server. performing a scanning operation to identify a wireless communication network which is identified by a wireless network identifier; receiving, during the scanning operation, from the wireless communication network one or more hotspot aggregator identifiers, each said hotspot aggregator identifier identifying a hotspot aggregator made available via the identified wireless communication network; displaying on the display a user input prompt prompting the user for credentials for one of hotspot aggregators (150, 152) made available by the identified wireless communication network receiving the credentials for the one of the hotspot aggregators from the user; sending, via the wireless communication network, the received credentials to the hotspot aggregator server; and receiving a response from the hotspot aggregator server.
The crystalline form Mod. I of Formula I, which has an X-ray powder diffraction diagram with peaks at 4.01° (±0.1°), 7.85° (±0.1°), 9.94° (±0.1°), 13.04° (±0.1°), 19.08° (±0.1°), 19.46° (±0.1°), 20.10° (±0.1°), 21.82° (±0.1°), 22.49° (±0.1°), 23.76° (±0.1°), 24.26° (±0.1°), 27.17° (±0.1°), 28.52° (±0.1°) and 30.48° (±0.1°) 2θ, when analyzed with X-ray diffraction CuKa.
A method for aggregating content from more than one domain stored on a memory of a device, each domain representing a logical collection of resources separate from another domain and including one or more policies regarding use or access of the domain resources, the method comprising: generating a query on a device comprising a search request generated based on information provided by a user; determining available domains on the device; scanning the available domains based on the query to obtain content related to the query from the available domains; aggregating the related content from the available domains while maintaining said policies; and presenting the aggregated related content to a user of the device. generating a query on a device comprising a search request generated based on information provided by a user; determining available domains on the device; scanning the available domains based on the query to obtain content related to the query from the available domains; aggregating the related content from the available domains while maintaining said policies; and presenting the aggregated related content to a user of the device.
Vacuum interrupter arrangement for a circuit breaker, comprising at least a first cylindrical shaped vacuum insert, within which a pair of corresponding electrical contacts (3a, 4a; 3b, 4b) is coaxially arranged, consisting of a fixed electrical contact (3a; 3b) which is attached to the vacuum insert (1; 2) and an axial movable electrical contact (4a; 4b) which is operated by a pushrod (7a, 7b), and wherein a second cylindrical shaped vacuum insert is coaxially arranged to the first cylindrical shaped vacuum insert, characterised in that both vacuum inserts (1, 2) are coaxially surrounded by an outer vacuum container in order to form a double contact gap version.
A method for network-controlled filtering of detected cell reporting, the method comprising: receiving, at a User Equipment, UE, a network-based request to report detectable neighboring cells; receiving, at the UE, cell data associated with one or more neighboring cells; characterized in that the request includes at least mobility filtering criteria and in that the method comprises: determining, at the UE, which of the one or more neighboring cells meets or exceeds the mobility filtering criteria based at least on the cell data; and in response to determining that at least one neighboring cell meets or exceeds the mobility filtering criteria, communicating, to the network, a detected cell report that identifies the at least one neighboring cell that has been determined to meet or exceed the mobility filtering criteria. receiving, at a User Equipment, UE, a network-based request to report detectable neighboring cells; receiving, at the UE, cell data associated with one or more neighboring cells; characterized in that the request includes at least mobility filtering criteria and in that the method comprises: determining, at the UE, which of the one or more neighboring cells meets or exceeds the mobility filtering criteria based at least on the cell data; and in response to determining that at least one neighboring cell meets or exceeds the mobility filtering criteria, communicating, to the network, a detected cell report that identifies the at least one neighboring cell that has been determined to meet or exceed the mobility filtering criteria. determining, at the UE, which of the one or more neighboring cells meets or exceeds the mobility filtering criteria based at least on the cell data; and in response to determining that at least one neighboring cell meets or exceeds the mobility filtering criteria, communicating, to the network, a detected cell report that identifies the at least one neighboring cell that has been determined to meet or exceed the mobility filtering criteria.
A method for cell handover, performed by a terminal, the method comprising: receiving a handover command and a timing sequence relationship from a base station, the handover command being configured to instruct the terminal to perform a handover to one of at least two target cells, and the timing sequence relationship being configured to indicate whether any two cells of the at least two target cells are in slot synchronization with each other so that time-domain resources for synchronization signals for the two cells are the same; performing synchronization with a first cell of the at least two target cells; initiating a handover to the first cell based on a result of the synchronization with the first cell; determining whether a failure of the handover to the first cell occurs; determining a second cell from the at least two target cells in response to the failure of the handover to the first cell, the second cell being in slot synchronization with the first cell; and initiating a connection reestablishment to the second cell based on the result of the synchronization with the first cell. receiving a handover command and a timing sequence relationship from a base station, the handover command being configured to instruct the terminal to perform a handover to one of at least two target cells, and the timing sequence relationship being configured to indicate whether any two cells of the at least two target cells are in slot synchronization with each other so that time-domain resources for synchronization signals for the two cells are the same; performing synchronization with a first cell of the at least two target cells; initiating a handover to the first cell based on a result of the synchronization with the first cell; determining whether a failure of the handover to the first cell occurs; determining a second cell from the at least two target cells in response to the failure of the handover to the first cell, the second cell being in slot synchronization with the first cell; and initiating a connection reestablishment to the second cell based on the result of the synchronization with the first cell.
A combine harvester comprising a separating device which extends in the longitudinal direction of the combine harvester and which has upstream thereof a tangentially disposed conveyor drum (8, 8') which has mutually circumferentially spaced guide plates which are arranged in substantially axis-parallel relationship and which are supported on the peripheral surface of the conveyor drum (8, 8') by way of support elements arranged to extend circumferentially between respectively adjacent guide plates, characterised in that the support elements extend in the radial direction over the entire free peripheral surface of the conveyor drum (8, 8') between the adjacent guide plates.
Underwater aerial for attachment to an aerial carrier, in particular to a hull of a U-boat, with at least one electroacoustic structural unit that comprises a reflector constructed as a spring-mass system with a metallic plate bar as mass and with an elastic soft substance body arranged in the direction of the incident sound behind the metal plate bar as a spring and comprises a converter arrangement set in front of the reflector in the direction of the incident sound, which arrangement consists of a plurality of electroacoustic converters, in particular hydrophones that are arranged in adjacent rows with spacing and fastened to the metal plate bar characterised by that the at least one electroacoustic structural unit is received in an acoustically transparent enveloping volume segment and is fastened via the soft substance body to the boundary volume segment, and that the enveloping volume segment comprises shanks (141, 142) and is fixed via acoustic decoupling means with the shanks (141, 142) on the end side to the aerial carrier.