Pipette - for a pipette system, which consists of a pipette and a syringe, where the syringe has a cylinder with a fastening portion realized preferably as a flange and a plunger with a plunger head which projects out of the end of the cylinder even when the plunger has been completely inserted into the cylinder, having a pipette housing which has a longitudinal axis, - wherein a syringe to be handled with the pipette is insertable with its fastening portion and plunger head into the pipette housing and is removable or discardable from said pipette housing in the direction of the longitudinal axis of the pipette housing, i.e. axially, having an axially accessible opening (9.1) on the pipette housing for the fastening portion of the syringe, having an axially accessible cylinder gripping device, mounted fixed in position in the pipette housing, for the fastening portion of a syringe, having a plunger adjusting device which is axially displaceable in the pipette housing, having an axially accessible plunger gripping device for the plunger head of a syringe, said plunger gripping device being mounted on the plunger adjusting device and being axially displaceable with said plunger adjusting device and having an actuating device for the plunger gripping device, wherein, by actuating the actuating device, the plunger gripping device is movable from a grip position into a release position, in which the plunger head of a syringe is released for removal or picking up, characterized in that, the actuating device for the plunger gripping device is mounted on the plunger adjusting device and is axially displaceable with said plunger adjusting device. - for a pipette system, which consists of a pipette and a syringe, where the syringe has a cylinder with a fastening portion realized preferably as a flange and a plunger with a plunger head which projects out of the end of the cylinder even when the plunger has been completely inserted into the cylinder, having a pipette housing which has a longitudinal axis, - wherein a syringe to be handled with the pipette is insertable with its fastening portion and plunger head into the pipette housing and is removable or discardable from said pipette housing in the direction of the longitudinal axis of the pipette housing, i.e. axially, having an axially accessible opening (9.1) on the pipette housing for the fastening portion of the syringe, having an axially accessible cylinder gripping device, mounted fixed in position in the pipette housing, for the fastening portion of a syringe, having a plunger adjusting device which is axially displaceable in the pipette housing, having an axially accessible plunger gripping device for the plunger head of a syringe, said plunger gripping device being mounted on the plunger adjusting device and being axially displaceable with said plunger adjusting device and having an actuating device for the plunger gripping device, wherein, by actuating the actuating device, the plunger gripping device is movable from a grip position into a release position, in which the plunger head of a syringe is released for removal or picking up, characterized in that, the actuating device for the plunger gripping device is mounted on the plunger adjusting device and is axially displaceable with said plunger adjusting device.