A perfusion loop assembly for an ex vivo liver perfusion comprising - at least one pump, in particular only one pump, for providing a fluid flow of a perfusion fluid through a first branch line and a second branch line; - the first branch line being configured to provide a first portion of the perfusion fluid to the hepatic artery of the liver; the first branch line being coupled with at least one first gas exchanger, in particular only one first gas exchanger, - the second branch line being configured to provide a second portion of the perfusion fluid to the portal vein of the liver; the second branch line further comprising at least one first valve for controlling the flow of the perfusion fluid into the portal vein of the liver, - a liver chamber assembly configured to hold the liver ex vivo, - a liver outlet line configured to be attached to the vena cava of the ex vivo liver, - at least one reservoir connected to the liver outlet line and upstream from the at least one pump, - wherein the first branch line, the second branch line and / or the liver outlet line comprise an interface, in particular a cannulation configured to be inserted into the hepatic artery of the liver, the portal vein and / or the vena cava respectively; - wherein the first branch line, the second branch line and / or the outlet line comprise at least one flow rate sensor (114, 124, 143) and/or at least one pressure sensor (113, 123, 141), and - wherein a flow throttling in the at least one valve of the second branch line, and / or in a valve in a bypass that is provided from the first branch line downstream of the first gas exchanger to the liver outlet line thus bypassing the liver chamber assembly, and/or in a valve in a bypass that is established between the first branch line and the second branch line, and/or in a valve (141 a) in the liver outlet line is accomplished over one or multiple stages, which are each made up of individual constrictions, in particular manually and / or automatically adjustable constrictions. - at least one pump, in particular only one pump, for providing a fluid flow of a perfusion fluid through a first branch line and a second branch line; - the first branch line being configured to provide a first portion of the perfusion fluid to the hepatic artery of the liver; the first branch line being coupled with at least one first gas exchanger, in particular only one first gas exchanger, - the second branch line being configured to provide a second portion of the perfusion fluid to the portal vein of the liver; the second branch line further comprising at least one first valve for controlling the flow of the perfusion fluid into the portal vein of the liver, - a liver chamber assembly configured to hold the liver ex vivo, - a liver outlet line configured to be attached to the vena cava of the ex vivo liver, - at least one reservoir connected to the liver outlet line and upstream from the at least one pump, - wherein the first branch line, the second branch line and / or the liver outlet line comprise an interface, in particular a cannulation configured to be inserted into the hepatic artery of the liver, the portal vein and / or the vena cava respectively; - wherein the first branch line, the second branch line and / or the outlet line comprise at least one flow rate sensor (114, 124, 143) and/or at least one pressure sensor (113, 123, 141), and - wherein a flow throttling in the at least one valve of the second branch line, and / or in a valve in a bypass that is provided from the first branch line downstream of the first gas exchanger to the liver outlet line thus bypassing the liver chamber assembly, and/or in a valve in a bypass that is established between the first branch line and the second branch line, and/or in a valve (141 a) in the liver outlet line is accomplished over one or multiple stages, which are each made up of individual constrictions, in particular manually and / or automatically adjustable constrictions.