An endoscope puncture needle comprising: an outer sheath which is insertable into a channel of an endoscope and has a coil shape; a needle tube having a needle tip and arranged inside the outer sheath; and an operation section connected to a proximal end of the outer sheath and configured to advance and retract the needle tube with respect to the outer sheath, wherein the operation section includes: an operation main body connected to the proximal end of the outer sheath; a needle slider connected to a proximal end of the needle tube and provided to be movable along a longitudinal axis of the operation main body with respect to the operation main body; and an engaging mechanism in which the needle slider is engaged to the operation main body in a longitudinal axial direction of the operation main body, characterized in that the endoscope puncture needle further comprises: a proximal-end-side inner tube arranged at an inside of a proximal end of the outer sheath and made of plastics; and a distal-end-side inner tube arranged at an inside of a distal end section of the outer sheath, through which the needle tube is insertable, and made of plastics, the distal-end-side inner tube having an inner circumferential surface that is relatively harder than the proximal-end-side inner tube, and a distal end of the needle tube is arranged inside the distal-end-side inner tube when the needle slider is engaged to the operation main body. an outer sheath which is insertable into a channel of an endoscope and has a coil shape; a needle tube having a needle tip and arranged inside the outer sheath; and an operation section connected to a proximal end of the outer sheath and configured to advance and retract the needle tube with respect to the outer sheath, wherein the operation section includes: an operation main body connected to the proximal end of the outer sheath; a needle slider connected to a proximal end of the needle tube and provided to be movable along a longitudinal axis of the operation main body with respect to the operation main body; and an engaging mechanism in which the needle slider is engaged to the operation main body in a longitudinal axial direction of the operation main body, an operation main body connected to the proximal end of the outer sheath; a needle slider connected to a proximal end of the needle tube and provided to be movable along a longitudinal axis of the operation main body with respect to the operation main body; and an engaging mechanism in which the needle slider is engaged to the operation main body in a longitudinal axial direction of the operation main body, characterized in that the endoscope puncture needle further comprises: a proximal-end-side inner tube arranged at an inside of a proximal end of the outer sheath and made of plastics; and a distal-end-side inner tube arranged at an inside of a distal end section of the outer sheath, through which the needle tube is insertable, and made of plastics, the distal-end-side inner tube having an inner circumferential surface that is relatively harder than the proximal-end-side inner tube, and a distal end of the needle tube is arranged inside the distal-end-side inner tube when the needle slider is engaged to the operation main body. a proximal-end-side inner tube arranged at an inside of a proximal end of the outer sheath and made of plastics; and a distal-end-side inner tube arranged at an inside of a distal end section of the outer sheath, through which the needle tube is insertable, and made of plastics, the distal-end-side inner tube having an inner circumferential surface that is relatively harder than the proximal-end-side inner tube, and a distal end of the needle tube is arranged inside the distal-end-side inner tube when the needle slider is engaged to the operation main body.