A method for real-time detection of and protection from malware in a kernel mode, comprising: detecting a file operation request initiated by a process running in user mode; performing malware detection analytics on a file buffer associated with the detected file operation request to detect behavior indicating presence of malware; identifying, responsive to detecting the behavior indicating the presence of the malware, the process responsible for initiating the detected file operation request; performing a search for the identified process on at least one of a blacklist of programs or a whitelist of programs to determine whether the identified process is a trusted process; and responsive to determining that the identified process is not a trusted process: executing a malware remediation action against the identified process, and transmitting information describing the malware to a client device, wherein the detecting of the file operation request comprises: determining, from a file handle corresponding to the file operation request, whether the file operation request corresponds to an operation of interest; and responsive to determining that the file operation request corresponds to an operation of interest, intercepting the file operation request; and wherein the intercepting of the file operation request comprises: determining, by a filter manager, whether a minifilter driver of a plurality of minifilter drivers is registered to intercept the operation of interest; and responsive to determining that the minifilter driver is registered to intercept the operation of interest, transmitting, by the filter manager, the file operation request to the minifilter driver to perform the malware detection analytics. detecting a file operation request initiated by a process running in user mode; performing malware detection analytics on a file buffer associated with the detected file operation request to detect behavior indicating presence of malware; identifying, responsive to detecting the behavior indicating the presence of the malware, the process responsible for initiating the detected file operation request; performing a search for the identified process on at least one of a blacklist of programs or a whitelist of programs to determine whether the identified process is a trusted process; and responsive to determining that the identified process is not a trusted process: executing a malware remediation action against the identified process, and transmitting information describing the malware to a client device, executing a malware remediation action against the identified process, and transmitting information describing the malware to a client device, wherein the detecting of the file operation request comprises: determining, from a file handle corresponding to the file operation request, whether the file operation request corresponds to an operation of interest; and responsive to determining that the file operation request corresponds to an operation of interest, intercepting the file operation request; and determining, from a file handle corresponding to the file operation request, whether the file operation request corresponds to an operation of interest; and responsive to determining that the file operation request corresponds to an operation of interest, intercepting the file operation request; and wherein the intercepting of the file operation request comprises: determining, by a filter manager, whether a minifilter driver of a plurality of minifilter drivers is registered to intercept the operation of interest; and responsive to determining that the minifilter driver is registered to intercept the operation of interest, transmitting, by the filter manager, the file operation request to the minifilter driver to perform the malware detection analytics. determining, by a filter manager, whether a minifilter driver of a plurality of minifilter drivers is registered to intercept the operation of interest; and responsive to determining that the minifilter driver is registered to intercept the operation of interest, transmitting, by the filter manager, the file operation request to the minifilter driver to perform the malware detection analytics.