mhurhangee/ep-ind-claims huggingface dataset:
A pharmaceutical composition of isolated microvesicles for use in the therapy of skin, wherein the isolated microvesicles are prepared with a method comprising the steps of: (a) obtaining a biological fluid containing microvesicles; (b) clarifying the biological fluid to remove cellular debris; (c) precipitating the microvesicles by adding a precipitating agent which is polyethylene glycol to the clarified biological fluid; (d) collecting the precipitated microvesicles; (e) washing the precipitated microvesicles to remove the precipitating agent; and (f) optionally suspending the microvesicles in a solution for storage or subsequent use to produce an isolated preparation of microvesicles, wherein the microvesicles are isolated without damaging the structural or functional integrity of the microvesicles, and wherein the therapy of skin comprises regenerating at least one tissue in a patient with diseased, damaged, or missing skin selected from a group consisting of epithelial tissue, stromal tissue, nerve tissue, vascular tissue and adnexal structures. (a) obtaining a biological fluid containing microvesicles; (b) clarifying the biological fluid to remove cellular debris; (c) precipitating the microvesicles by adding a precipitating agent which is polyethylene glycol to the clarified biological fluid; (d) collecting the precipitated microvesicles; (e) washing the precipitated microvesicles to remove the precipitating agent; and (f) optionally suspending the microvesicles in a solution for storage or subsequent use to produce an isolated preparation of microvesicles, wherein the microvesicles are isolated without damaging the structural or functional integrity of the microvesicles, and wherein the therapy of skin comprises regenerating at least one tissue in a patient with diseased, damaged, or missing skin selected from a group consisting of epithelial tissue, stromal tissue, nerve tissue, vascular tissue and adnexal structures.
Method for 3D radius correction in CNC milling with the steps: - using an NC program to predetermine a mill path on a workpiece in the form of positions of a mill cutter tip, wherein the mill path has been calculated for an original mill in order to produce a surface contour on the workpiece, - predetermine the original mill including its dimensions (R, r), for which the mill path has been calculated to produce the surface contour, - predetermine differences in dimension (ΔR, Δr) of a mill which is actually available, with which the machining of the workpiece can take place, from the original mill, - predetermine a surface normal ( f s) of a face milling surface and a surface normal ( f u) of a circumferential milling surface for each position of the mill cutter tip, - predetermine a mill orientation ( w), which specifies the spatial orientation of the mill axis, for each position of the mill path, - for each position of the mill path, determine a correction vector from the mill orientation ( w) and the differences in dimension (ΔR, Δr) of the mill which is actually available and the surface normals for face milling ( f s) and the surface normals for circumferential milling ( f u) and - machining the workpiece in order to produce the surface contour by simultaneous face and circumferential milling when the mill which is actually available passes through the mill path predetermined by the NC program, by correcting the differences in dimension (ΔR, Δr) with the correction vector. - using an NC program to predetermine a mill path on a workpiece in the form of positions of a mill cutter tip, wherein the mill path has been calculated for an original mill in order to produce a surface contour on the workpiece, - predetermine the original mill including its dimensions (R, r), for which the mill path has been calculated to produce the surface contour, - predetermine differences in dimension (ΔR, Δr) of a mill which is actually available, with which the machining of the workpiece can take place, from the original mill, - predetermine a surface normal ( f s) of a face milling surface and a surface normal ( f u) of a circumferential milling surface for each position of the mill cutter tip, - predetermine a mill orientation ( w), which specifies the spatial orientation of the mill axis, for each position of the mill path, - for each position of the mill path, determine a correction vector from the mill orientation ( w) and the differences in dimension (ΔR, Δr) of the mill which is actually available and the surface normals for face milling ( f s) and the surface normals for circumferential milling ( f u) and - machining the workpiece in order to produce the surface contour by simultaneous face and circumferential milling when the mill which is actually available passes through the mill path predetermined by the NC program, by correcting the differences in dimension (ΔR, Δr) with the correction vector.
Multi-pole assembly consisting of a catheter having a catheter shaft; the catheter shaft has at least one lumen and has a distal and a proximal end; and consisting of an electrode array being self-expandable from a collapsed structure to an expanded structure and being arranged at the distal end of the catheter shaft when expanded, and wherein the electrode array comprises a plurality of multipole coils with poles wherein each multipole coil is made of a plurality of insulated coiled wires running in parallel and the poles are bare areas of the insulating layer and are formed by spot-removing the insulating layer; the multipole coils are grouped around the longitudinal axis of the assembly and each multipole coil has an electrical supply region and a sensing region, characterized in that the sensing region of each coil has a plurality of poles being arranged adjacent to each other; wherein each coil has a lumen through which a preformed wire of shape memory metal is guided, wherein the preformed wire has a distal and a proximal end, and wherein the expanded electrode array is shaped according to the pre-shaped wire of shape memory metal running inside the coils so that in the position of use the poles have close contact to the endocard tissue.
A thermal conducting sheet, comprising: a binder resin; insulating-coated carbon fibers; and a thermal conducting filler other than the insulating-coated carbon fibers, wherein the insulating-coated carbon fibers comprise carbon fibers and a coating film over at least a part of a surface of the carbon fibers, the coating film being formed of a cured product of a polymerizable material, and wherein the polymerizable material comprises a compound that comprises 2 or more radically polymerizable double bonds. a binder resin; insulating-coated carbon fibers; and a thermal conducting filler other than the insulating-coated carbon fibers, wherein the insulating-coated carbon fibers comprise carbon fibers and a coating film over at least a part of a surface of the carbon fibers, the coating film being formed of a cured product of a polymerizable material, and wherein the polymerizable material comprises a compound that comprises 2 or more radically polymerizable double bonds.
Multiple door, having at least a structure with pillars and longitudinal members that can be housed in the rear of the access threshold of a façade or similar door, two or more wind up drums (31a and 31b) with two or more closure elements (32a and 32b) made from rigid slats or wind up sheets, these drums being held by supports on axles (33a and 33b), which are connected to an activation motor (5a and 5b), the closure elements being arranged so that they can slide along pairs of vertical longitudinal guides (6a and 6b), said guides (6a and 6b) having openings (61a and 61b) arranged in a stepped fashion for the insertion of the closure elements (32a and 32b) in a consecutive position in accordance with the sequence of arrangement of the respective drums (31a and 31b); characterized in that: said axles (33a and 33b) are aligned in parallel onto said pillars of the structure, behind the lintel or the doorpost of the threshold, and said axles (33a and 33b) are anchored to the side of the pillars of the structure by supports (4a and 4b); and said guides (6a and 6b) are arranged on the inner facing sides of the pillars for the parallel displacement of said closure elements (32a and 32b). said axles (33a and 33b) are aligned in parallel onto said pillars of the structure, behind the lintel or the doorpost of the threshold, and said axles (33a and 33b) are anchored to the side of the pillars of the structure by supports (4a and 4b); and said guides (6a and 6b) are arranged on the inner facing sides of the pillars for the parallel displacement of said closure elements (32a and 32b).
A power tool configured to receive an alternating current input signal, comprising: an electric motor; a phase-controlled switch coupled in series with the motor: a motor control module interfaced with the phase-controlled switch that modulates the conductive state of the phase-controlled switch in relation to a zero-crossing of the AC input signal; and a protective control module characterised in that thea protective control module that measures voltage across the phase-controlled switch during a non-conductive state of the phase-controlled switch after a zero-crossing of the AC input signal but prior to closing of the phase-controlled switch and disables the power tool when the measured voltage indicates a malfunction of the phase controlled switch. an electric motor; a phase-controlled switch coupled in series with the motor: a motor control module interfaced with the phase-controlled switch that modulates the conductive state of the phase-controlled switch in relation to a zero-crossing of the AC input signal; and a protective control module characterised in that thea protective control module that measures voltage across the phase-controlled switch during a non-conductive state of the phase-controlled switch after a zero-crossing of the AC input signal but prior to closing of the phase-controlled switch and disables the power tool when the measured voltage indicates a malfunction of the phase controlled switch. a motor control module interfaced with the phase-controlled switch that modulates the conductive state of the phase-controlled switch in relation to a zero-crossing of the AC input signal; and a protective control module characterised in that thea protective control module that measures voltage across the phase-controlled switch during a non-conductive state of the phase-controlled switch after a zero-crossing of the AC input signal but prior to closing of the phase-controlled switch and disables the power tool when the measured voltage indicates a malfunction of the phase controlled switch.
A multilayer filter medium comprising three or more nonwoven fabric layers superposed together and having two or more interlayer regions each formed by two adjacent layers of the nonwoven fabric layers, wherein a first interlayer region of the interlayer regions contains functional particles A having an average particle diameter of 50 to 100 μm, and a second interlayer region selected from the interlayer regions excluding the first interlayer region contains functional particles B having an average particle diameter of 150 to 500 μm. a first interlayer region of the interlayer regions contains functional particles A having an average particle diameter of 50 to 100 μm, and a second interlayer region selected from the interlayer regions excluding the first interlayer region contains functional particles B having an average particle diameter of 150 to 500 μm.
A method (500, 600, 700) comprising: performing compression operations on a memory block (504, 604); determining that the memory block is a constant data block comprised of only repeat instances of a constant value (506, 606, 704), wherein the determination (506, 606, 704) is performed concurrently with the compression operations on the memory block (504, 604); and associating a first indication with the memory block based on the determination (506, 606, 704), characterised in that the first indication is used for controlling whether to abort the compression operations or whether to discard a compressed memory block generated from the compression operations, wherein the method further comprises responsive to a request for the memory block, generating a copy of the memory block using the constant value when the memory block is associated with the first indication, and wherein the compression operations are performed based on a DEFLATE or a Lempel-Ziv-Oberhumer, LZO, compression scheme. performing compression operations on a memory block (504, 604); determining that the memory block is a constant data block comprised of only repeat instances of a constant value (506, 606, 704), wherein the determination (506, 606, 704) is performed concurrently with the compression operations on the memory block (504, 604); and associating a first indication with the memory block based on the determination (506, 606, 704), characterised in that the first indication is used for controlling whether to abort the compression operations or whether to discard a compressed memory block generated from the compression operations, wherein the method further comprises responsive to a request for the memory block, generating a copy of the memory block using the constant value when the memory block is associated with the first indication, and wherein the compression operations are performed based on a DEFLATE or a Lempel-Ziv-Oberhumer, LZO, compression scheme.
A composition comprising an aqueous quality control or calibration reagent disposed in a closed system, the composition comprising: urea present in a concentration in a range of from about 0.1 mM to about 150 mM; at least one buffer; and at least one amino acid-containing composition having at least one available primary or secondary amine, wherein the ratio of urea to the at least one amino acid-containing composition is in a range of from about 0.1:1 to about 100:1. urea present in a concentration in a range of from about 0.1 mM to about 150 mM; at least one buffer; and at least one amino acid-containing composition having at least one available primary or secondary amine, wherein the ratio of urea to the at least one amino acid-containing composition is in a range of from about 0.1:1 to about 100:1.
An orchestration method, for execution by an orchestrator for a Virtual Network Platform as a Service, VNPaaS, to orchestrate the management of a Network Service, NS, comprising: - selecting an orchestration zone for each of a plurality of Virtual Network Functions, VNFs, (401, 402, 403) used in the NS based on selected deployment locations, wherein each orchestration zone corresponds to a logical partition of a Network Function Virtualization Infrastructure, NFVI, and comprises at least one VNF, wherein each orchestration zone is managed by an orchestration agent; - associating sub-services to said selected orchestration zones, said sub-services being obtained from a decomposition of the NS into a number of sub-services equal to a number of orchestration zones selected and each sub-service comprising at least one of the plurality of VNFs (401, 402, 403); and - initiating deployment of the sub-services in the selected orchestration zones, wherein initiating deployment includes instructing the orchestration agents in the selected orchestration zones to deploy the sub-services. - selecting an orchestration zone for each of a plurality of Virtual Network Functions, VNFs, (401, 402, 403) used in the NS based on selected deployment locations, wherein each orchestration zone corresponds to a logical partition of a Network Function Virtualization Infrastructure, NFVI, and comprises at least one VNF, wherein each orchestration zone is managed by an orchestration agent; - associating sub-services to said selected orchestration zones, said sub-services being obtained from a decomposition of the NS into a number of sub-services equal to a number of orchestration zones selected and each sub-service comprising at least one of the plurality of VNFs (401, 402, 403); and - initiating deployment of the sub-services in the selected orchestration zones, wherein initiating deployment includes instructing the orchestration agents in the selected orchestration zones to deploy the sub-services.
Cleaning textile comprising a cleaning side having a cleaning surface which on the external circumference is delimited by a periphery, characterized in that the cleaning surface, when viewed transversely to the wiping direction of the cleaning textile, in the centre has a lower pile density (10, 13, 16) than on the periphery.
A measuring device, comprising: a first electrode and a second electrode configured to be immersed in sample water stored in a measuring tank; a motor configured to rotate the first electrode; and a controller configured to operate, based on measurement results of current flowing through the sample water, in a measuring mode, wherein in the measuring mode, the controller is configured to calculate a concentration of a measurement target in the sample water, and the motor is configured to change a rotational velocity of the motor, wherein the motor is further configured to change the direction of rotation of the motor, and wherein the controller is further configured to control the direction of rotation of the motor. a first electrode and a second electrode configured to be immersed in sample water stored in a measuring tank; a motor configured to rotate the first electrode; and a controller configured to operate, based on measurement results of current flowing through the sample water, in a measuring mode, wherein in the measuring mode, the controller is configured to calculate a concentration of a measurement target in the sample water, and the motor is configured to change a rotational velocity of the motor, wherein the motor is further configured to change the direction of rotation of the motor, and wherein the controller is further configured to control the direction of rotation of the motor. the motor is further configured to change the direction of rotation of the motor, and wherein the controller is further configured to control the direction of rotation of the motor.
A spacecraft for the recovery and maintenance of satellites and similar, with its own drive for purposes of locomotion, a device for purposes of working on a structure, and with a manipulator, on which the device is mounted, wherein the device has an interface for attachment to the manipulator, a tool holder for the accommodation of a tool, and two grippers (2, 4) for purposes of gripping and holding the structure to be worked on, wherein the tool holder is arranged between the grippers (2, 4), and the grippers (2, 4) can be moved towards each other, and wherein the grippers (2, 4) can be pivoted towards each other about an axis of rotation, fingers (24, 26, 28) of the grippers (2, 4) are pre-loaded in the closed position in the unpowered state, and the fingers (24, 26, 28) of the grippers (2, 4) can be locked in at least one end position.
A compound represented by the following structural formula: or a pharmaceutically acceptable salt thereof, wherein: R 1 is a phenyl group optionally substituted with one or more substituents selected from the group consisting of halogen, cyano, nitro, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 alkylamino, C1-C6 dialkylamino, aryl, aryloxy, -OH, C1-C6 alkoxy, -O-[CH 2] p -O- and -[CH 2] q -; and -N(R 2 R 3) is an unsubstituted pyrrolidinyl group; each p is independently 1, 2, 3 or 4; and each q is independently 3, 4, 5 or 6; Y is -H; wherein, in the above definitions, the term "aryl" denotes a carbocyclic aromatic ring having 6 to 14 carbon atoms or an aromatic ring having 5 to 14 ring atoms selected from carbon and at least one heteroatom; X is -(CR 5 R 6) n -; and R 4 is -CN, -NCS, -NO 2, or a halogen; R 5 and R 6 are each independently -H; -OH; a halogen; or a C1-C6 alkoxy or C1-C6 alkyl group; and n is 1, 2, 3, 4, 5 or 6. R 1 is a phenyl group optionally substituted with one or more substituents selected from the group consisting of halogen, cyano, nitro, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 alkylamino, C1-C6 dialkylamino, aryl, aryloxy, -OH, C1-C6 alkoxy, -O-[CH 2] p -O- and -[CH 2] q -; and -N(R 2 R 3) is an unsubstituted pyrrolidinyl group; each p is independently 1, 2, 3 or 4; and each q is independently 3, 4, 5 or 6; Y is -H; wherein, in the above definitions, the term "aryl" denotes a carbocyclic aromatic ring having 6 to 14 carbon atoms or an aromatic ring having 5 to 14 ring atoms selected from carbon and at least one heteroatom; X is -(CR 5 R 6) n -; and R 4 is -CN, -NCS, -NO 2, or a halogen; R 5 and R 6 are each independently -H; -OH; a halogen; or a C1-C6 alkoxy or C1-C6 alkyl group; and n is 1, 2, 3, 4, 5 or 6.
Microdialysis sampling catheter or probe configured to be placed on the surface of a vital human or animal organ for sampling metabolic substances that indicate the metabolic conditions of the organ from the surface of the organ and further configured to be temporarily attached to the outside surface of the vital organ to sample said metabolic substances via a semi-permeable membrane attached to the catheter or probe on the side facing the surface of the organ; wherein the probe comprises an inlet and an outlet for the perfusate; characterised in that on the end or tip of the probe opposite the inlet and outlet is placed a ring designed for temporarily securing the probe to a vital organ via at least one suture.
An access system, comprising: a Customer Premise Equipment sub-system, a Mobile Internet Device sub-system and a connection interface, wherein the connection interface is configured to provide a channel for communication between the CPE sub-system and the MID sub-system; the CPE sub-system is configured to receive a connection request for carrying out a data connection with a WAN, send, when determining that the CPE sub-system itself is not able to carry out a wired connection with the WAN, the connection request to the MID sub-system through the connection interface so that the data connection between the CPE sub-system and the WAN is carried out through a wireless connection between the MID sub-system and the WAN and a data communication between the CPE sub-system and the MID sub-system; wherein determining that the CPE sub-system itself is not able to carry out a wired connection with the WAN comprises: judging whether the wired access of the WAN connected with the CPE sub-system has been disabled; wherein the basis for the CPE sub-system judging whether the wired access of the WAN connected with the CPE sub-system itself has been disabled is: a parameter stored in a memory when a user sets whether to disable the wired access of the WAN connected with the CPE sub-system and the MID sub-system is configured to receive a connection request for carrying out a data connection with the WAN, send, when determining that the MID sub-system itself is not able to carry out a wireless connection with the WAN, the connection request to the CPE sub-system through the connection interface so that the data connection between the MID sub-system and the WAN is carried out through a wired connection between the CPE sub-system and the WAN and a data communication between the MID sub-system and the CPE sub-system; wherein determining that the MID sub-system itself is not able to carry out a wireless connection with the WAN comprises: judging whether the wireless access of the WAN connected with the MID sub-system has been disabled; wherein the basis for the MID sub-system judging whether the wireless access of the WAN connected with the MID sub-system itself has been disabled is: a parameter stored in a memory when a user sets whether to disable the wireless access of the WAN connected with the MID sub-system.