A layer or three-dimensional shaped body made of or with an organically modified polysiloxane or of a derivative thereof, the silicon atoms of which are partially replaced by other metal atoms, wherein the organic portion of the polysiloxane or derivative thereof has an organic network with (i) C=C addition polymers and/or thiol-ene addition products obtainable by 2- or multi-photon polymerization and bonded via carbon to silicon and optionally to other metal atoms, and (ii) organic molecules which are copolymerised via C=C double bonds or are bound into the organic network by a thiol-ene addition to double bonds or to SH groups of the organic radical, wherein the layer or body has two regions with different primary and/or secondary structures, obtainable by the following process: a) providing a substrate or mould, b) providing a material selected from organically modified polysiloxane-containing materials, wherein the provided material comprises the following components: (i) at least one organically modified polysiloxane having groups polymerisable via a 2- or multi-photon polymerisation reaction, in which the formation of either C=C addition polymers and/or thiol-ene addition products is possible, wherein at least part of said groups is attached to the polysiloxane via a carbon atom, and (ii) at least one organic monomer containing at least one radical which can be photochemically copolymerised with or added to radicals which are accessible to the same 2- or multi-photon polymerisation as the groups of the organically modified polysiloxane according to (i), (c) attaching or placing the provided material to or on the substrate or placing it in the mould, (d) selectively exposing a selected area of material on the substrate or in the mould using 2- or mulit-photon polymerisation, (e) thermal or photochemical treatment of all the material on the substrate or in the mould to solidify all the material on the substrate or in the mould, with the proviso that steps d) and e) may be carried out in any sequence. a) providing a substrate or mould, b) providing a material selected from organically modified polysiloxane-containing materials, wherein the provided material comprises the following components: (i) at least one organically modified polysiloxane having groups polymerisable via a 2- or multi-photon polymerisation reaction, in which the formation of either C=C addition polymers and/or thiol-ene addition products is possible, wherein at least part of said groups is attached to the polysiloxane via a carbon atom, and (ii) at least one organic monomer containing at least one radical which can be photochemically copolymerised with or added to radicals which are accessible to the same 2- or multi-photon polymerisation as the groups of the organically modified polysiloxane according to (i), (i) at least one organically modified polysiloxane having groups polymerisable via a 2- or multi-photon polymerisation reaction, in which the formation of either C=C addition polymers and/or thiol-ene addition products is possible, wherein at least part of said groups is attached to the polysiloxane via a carbon atom, and (ii) at least one organic monomer containing at least one radical which can be photochemically copolymerised with or added to radicals which are accessible to the same 2- or multi-photon polymerisation as the groups of the organically modified polysiloxane according to (i), (c) attaching or placing the provided material to or on the substrate or placing it in the mould, (d) selectively exposing a selected area of material on the substrate or in the mould using 2- or mulit-photon polymerisation, (e) thermal or photochemical treatment of all the material on the substrate or in the mould to solidify all the material on the substrate or in the mould,