A method for transmitting a demodulation reference signal, DMRS, for a physical uplink shared channel, PUSCH, in a wireless communication system, the method comprising: generating a plurality of DMRS sequences associated with a plurality of layers respectively, wherein the plurality of DMRS sequences are generated based on different cyclic shifts allocated to the plurality of DMRS sequences, respectively, and any one orthogonal covering code, OCC, of either [1 1] or [1 -1], applied to each of the plurality of DMRS sequences, respectively; mapping the plurality of DMRS sequences to resource elements, REs; and transmitting the plurality of DMRS sequences to a base station, wherein the different cyclic shifts and the OCC are indicated by a cyclic shift field in a downlink control information, DCI, format received through a physical downlink control channel, PDCCH, wherein a first cyclic shift allocated to a first DMRS sequence, among the plurality of DMRS sequences, and a second cyclic shift allocated to a second DMRS sequence, among the plurality of DMRS sequences, have a maximum interval, wherein a third cyclic shift allocated to a third DMRS sequence, among the plurality of DMRS sequences, and a fourth cyclic shift allocated to a fourth DMRS sequence, among the plurality of DMRS sequences, have a maximum interval, and wherein signs of the OCC applied to each of the plurality of DMRS sequences are as follows: n DMRS Cyclic shift field 1 st slot 2 nd slot L0 L1 L2 L3 L0 L1 L2 L3 0 000 + + + + + + - - 6 001 + + + + + + - - 3 010 + + + + + + - - 4 011 + + + + - - + + 2 100 + + + + - - + + 8 101 + + + + - - + + 10 110 + + + + - - + + 9 111 + + + + + + - - where L0 corresponds to the first DMRS sequence, L1 corresponds to the second DMRS sequence, L2 corresponds to the third DMRS sequence, and L3 corresponds to the fourth DMRS sequence, and where n DMRS indicates cyclic shift values allocated to L0. generating a plurality of DMRS sequences associated with a plurality of layers respectively, wherein the plurality of DMRS sequences are generated based on different cyclic shifts allocated to the plurality of DMRS sequences, respectively, and any one orthogonal covering code, OCC, of either [1 1] or [1 -1], applied to each of the plurality of DMRS sequences, respectively; mapping the plurality of DMRS sequences to resource elements, REs; and transmitting the plurality of DMRS sequences to a base station, wherein the different cyclic shifts and the OCC are indicated by a cyclic shift field in a downlink control information, DCI, format received through a physical downlink control channel, PDCCH, wherein a first cyclic shift allocated to a first DMRS sequence, among the plurality of DMRS sequences, and a second cyclic shift allocated to a second DMRS sequence, among the plurality of DMRS sequences, have a maximum interval, wherein a third cyclic shift allocated to a third DMRS sequence, among the plurality of DMRS sequences, and a fourth cyclic shift allocated to a fourth DMRS sequence, among the plurality of DMRS sequences, have a maximum interval, and wherein signs of the OCC applied to each of the plurality of DMRS sequences are as follows: n DMRS Cyclic shift field 1 st slot 2 nd slot L0 L1 L2 L3 L0 L1 L2 L3 0 000 + + + + + + - - 6 001 + + + + + + - - 3 010 + + + + + + - - 4 011 + + + + - - + + 2 100 + + + + - - + + 8 101 + + + + - - + + 10 110 + + + + - - + + 9 111 + + + + + + - - where L0 corresponds to the first DMRS sequence, L1 corresponds to the second DMRS sequence, L2 corresponds to the third DMRS sequence, and L3 corresponds to the fourth DMRS sequence, and where n DMRS indicates cyclic shift values allocated to L0.