mhurhangee/ep-ind-claims huggingface dataset:
An in vitro process to assess the effectiveness of enzyme inhibition in angiotensin converting enzyme inhibitor therapy in a subject comprising: (a) in a blood sample or a blood derived sample provided from a subject treated with an ACE inhibitor; (b) taking at least two aliquots from the sample; (c) diluting said aliquots by different dilution factors, (d) measuring the ACE activity in the dilution samples; (e) defining a high dilution factor where the effect of the ACE inhibitor becomes negligible, wherein said dilution factor is at least 50, preferably at least 100; (f) defining a low reference dilution factor, said dilution factor being at most 10; (g) multiplying the measured activity values in each of the diluted samples by the respective dilution factor to obtain calculated ACE activity values for each dilution samples; (h) obtaining the level of ACE inhibition in the original sample by comparing the enzyme activity values determined at said low and high dilution factors in said dilution samples; (i) assessing the effectiveness of medical treatment by the ACE inhibitor in said subject by evaluating the calculated level of ACE inhibition, wherein a low enzyme inhibition is an indication of an ineffective therapy, and wherein a high enzyme inhibition is an indication of an effective therapy. (a) in a blood sample or a blood derived sample provided from a subject treated with an ACE inhibitor; (b) taking at least two aliquots from the sample; (c) diluting said aliquots by different dilution factors, (d) measuring the ACE activity in the dilution samples; (e) defining a high dilution factor where the effect of the ACE inhibitor becomes negligible, wherein said dilution factor is at least 50, preferably at least 100; (f) defining a low reference dilution factor, said dilution factor being at most 10; (g) multiplying the measured activity values in each of the diluted samples by the respective dilution factor to obtain calculated ACE activity values for each dilution samples; (h) obtaining the level of ACE inhibition in the original sample by comparing the enzyme activity values determined at said low and high dilution factors in said dilution samples; (i) assessing the effectiveness of medical treatment by the ACE inhibitor in said subject by evaluating the calculated level of ACE inhibition, wherein a low enzyme inhibition is an indication of an ineffective therapy, and wherein a high enzyme inhibition is an indication of an effective therapy.
Four-stroke reciprocating piston engine in a V configuration having 16 cylinders, having a counter-clockwise direction of rotation, having an ignition timing control which fires the cylinders A1 to A8 and B1 to B8 in one of the following firing sequences, wherein the direction of rotation and the cylinder numbering are defined in accordance with DIN ISO 1204: a) A1-B2-A5-B4-A7-B8-A3-A8-B5-A6-B7-A2-B3-A4-B1-B6 b) A1-B2-A5-A2-B3-A4-B1-A8-B5-A6-B7-B4-A7-B8-A3-B6 c) A1-B4-A3-B2-A7-B6-A5-B8-B3-A8-B7-A4-B5-A2-B1-A6 d) A1-B4-A3-B2-B5-A2-B1-A6-B3-A8-B7-A4-A7-B6-A5-B8 e) A1-B2-A6-B4-A8-A4-B1-A7-B6-A5-B8-A2-B3-B7-A3-B5 f) A1-B2-A6-B4-A8-B7-A3-A7-B6-A5-B8-A2-B3-A4-B1-B5 g) A1-B2-A6-A2-B3-A4-B1-A7-B6-A5-B8-B4-A8-B7-A3-B5 h) A1-B4-A3-B2-A8-B5-A6-B7-B3-A7-B8-A4-B6-A2-B1-A5 i) A1-B4-B8-A4-B6-A2-B1-A5-B3-A7-A3-B2-A8-B5-A6-B7 j) A1-B4-A3-B2-B6-A2-B1-A5-B3-A7-B8-A4-A8-B5-A6-B7 k) A1-B2-A6-B5-A8-A5-B1-A7-B6-A4-B8-A2-B3-B7-A3-B4 l) A1-B2-A6-B5-A8-B7-A3-A7-B6-A4-B8-A2-B3-A5-B1-B4 m) A1-B2-A6-A2-B3-A5-B1-A7-B6-A4-B8-B5-A8-B7-A3-B4 n) A1-B5-A3-B2-A8-B4-A6-B7-B3-A7-B8-A5-B6-A2-B1-A4 o) A1-B5-B8-A5-B6-A2-B1-A4-B3-A7-A3-B2-A8-B4-A6-B7 p) A1-B5-A3-B2-B6-A2-B1-A4-B3-A7-B8-A5-A8-B4-A6-B7. a) A1-B2-A5-B4-A7-B8-A3-A8-B5-A6-B7-A2-B3-A4-B1-B6 b) A1-B2-A5-A2-B3-A4-B1-A8-B5-A6-B7-B4-A7-B8-A3-B6 c) A1-B4-A3-B2-A7-B6-A5-B8-B3-A8-B7-A4-B5-A2-B1-A6 d) A1-B4-A3-B2-B5-A2-B1-A6-B3-A8-B7-A4-A7-B6-A5-B8 e) A1-B2-A6-B4-A8-A4-B1-A7-B6-A5-B8-A2-B3-B7-A3-B5 f) A1-B2-A6-B4-A8-B7-A3-A7-B6-A5-B8-A2-B3-A4-B1-B5 g) A1-B2-A6-A2-B3-A4-B1-A7-B6-A5-B8-B4-A8-B7-A3-B5 h) A1-B4-A3-B2-A8-B5-A6-B7-B3-A7-B8-A4-B6-A2-B1-A5 i) A1-B4-B8-A4-B6-A2-B1-A5-B3-A7-A3-B2-A8-B5-A6-B7 j) A1-B4-A3-B2-B6-A2-B1-A5-B3-A7-B8-A4-A8-B5-A6-B7 k) A1-B2-A6-B5-A8-A5-B1-A7-B6-A4-B8-A2-B3-B7-A3-B4 l) A1-B2-A6-B5-A8-B7-A3-A7-B6-A4-B8-A2-B3-A5-B1-B4 m) A1-B2-A6-A2-B3-A5-B1-A7-B6-A4-B8-B5-A8-B7-A3-B4 n) A1-B5-A3-B2-A8-B4-A6-B7-B3-A7-B8-A5-B6-A2-B1-A4 o) A1-B5-B8-A5-B6-A2-B1-A4-B3-A7-A3-B2-A8-B4-A6-B7 p) A1-B5-A3-B2-B6-A2-B1-A4-B3-A7-B8-A5-A8-B4-A6-B7.
An endless vehicle track comprising a body comprising an elastomeric material forming an outer surface displaying a series of ground engaging profiles longitudinally spaced along the outer surface, and an inner surface displaying a series of longitudinally spaced guide-drive lugs for retaining the track an the vehicle and/or driving the vehicle; characterized in that the inner surface comprises a urethane reinforcement material formed from an admixture comprising a castable urethane material, and wherein the guide drive lugs defining guide drive faces (204, 206) an upper flat face and a guide drive body are formed from the urethane reinforcement material and wherein the urethane reinforcement defines the inner surface of the body. characterized in that the inner surface comprises a urethane reinforcement material formed from an admixture comprising a castable urethane material, and wherein the guide drive lugs defining guide drive faces (204, 206) an upper flat face and a guide drive body are formed from the urethane reinforcement material and wherein the urethane reinforcement defines the inner surface of the body.
An optical system (12, 20) of a microlithographic projection exposure apparatus, comprising a) a polarization adjustment device which is capable of changing an input state of polarization to different elliptical output states of polarization, and b) a control unit which controls the polarization adjustment device, wherein the control unit is configured - to receive data relating to image placement errors occurring at a light sensitive surface on which features contained in a mask are imaged, and - to select the elliptical output state of polarization produced by the polarization adjustment device such that the image placement errors are reduced. a) a polarization adjustment device which is capable of changing an input state of polarization to different elliptical output states of polarization, and b) a control unit which controls the polarization adjustment device, wherein the control unit is configured - to receive data relating to image placement errors occurring at a light sensitive surface on which features contained in a mask are imaged, and - to select the elliptical output state of polarization produced by the polarization adjustment device such that the image placement errors are reduced. - to receive data relating to image placement errors occurring at a light sensitive surface on which features contained in a mask are imaged, and - to select the elliptical output state of polarization produced by the polarization adjustment device such that the image placement errors are reduced.
A fuel assembly (100, 200) for use in a core of a nuclear power reactor, the assembly comprising: a frame shaped and configured to fit within the nuclear reactor internal core structure; and a plurality of helically twisted fuel elements (102, 202) supported by the frame in a fuel rod bundle, each of the fuel elements (102, 202) comprising fissile material; wherein as viewed in a cross-section that is perpendicular to an axial direction of the fuel assembly (100, 200), the outermost fuel elements (102, 202) of the fuel rod bundle define a substantially circular perimeter; wherein the plurality of fuel elements (102, 202) are arranged into a mixed grid pattern that includes a first, rectangular grid pattern and a second, triangular grid pattern; characterized in that some of the plurality of fuel elements (102, 202) are separated from adjacent fuel elements (102, 202) by a common centerline-to-centerline distance, and a circumscribed diameter of some of the plurality of fuel elements (102, 202) equals the centerline-to-centerline distance. a frame shaped and configured to fit within the nuclear reactor internal core structure; and a plurality of helically twisted fuel elements (102, 202) supported by the frame in a fuel rod bundle, each of the fuel elements (102, 202) comprising fissile material; wherein as viewed in a cross-section that is perpendicular to an axial direction of the fuel assembly (100, 200), the outermost fuel elements (102, 202) of the fuel rod bundle define a substantially circular perimeter; wherein the plurality of fuel elements (102, 202) are arranged into a mixed grid pattern that includes a first, rectangular grid pattern and a second, triangular grid pattern;
A vehicle body frame of a saddle-ride-type vehicle which includes: a plurality of skeletal frames arranged to face each other in an opposed manner; and a cross frame which connects a pair of said skeletal frames arranged in an opposedly facing manner along the longitudinal direction of the vehicle body frame to each other, wherein through holes are formed in the skeletal frames arranged to face each other in an opposed manner, and the cross frame is joined to the skeletal frames at insertion portions thereof inserted into the through holes, characterised in that distal end portions of the cross frame are welded to inner surfaces of the through holes. a plurality of skeletal frames arranged to face each other in an opposed manner; and a cross frame which connects a pair of said skeletal frames arranged in an opposedly facing manner along the longitudinal direction of the vehicle body frame to each other, wherein through holes are formed in the skeletal frames arranged to face each other in an opposed manner, and the cross frame is joined to the skeletal frames at insertion portions thereof inserted into the through holes, characterised in that distal end portions of the cross frame are welded to inner surfaces of the through holes.
A vacuum coating and plasma treatment system comprising: a plasma assembly arranged to face a substrate, the plasma assembly including: a magnetron target (Ts) having a target surface; a magnetron cathode with a long edge, a short edge and a magnetic pole, said magnetic pole being arranged to form, in use, a sputtering racetrack within the magnetron target (Ts) and an electromagnetic barrier; an anode (As) electrically connected to the magnetron cathode; a magnetron cathode power supply (Ps) connected to the magnetron cathode and to the anode; at least two remote arc discharge electrodes (44; 28); a remote arc discharge power supply connected between the at least two remote arc discharge electrodes (44; 28), and arranged to generate at least one remote arc discharge separate from the magnetron cathode and adjacent to the magnetron target, such that, in use, the remote arc discharge extends along a direction parallel to the long edge of the magnetron cathode, and such that, in use, the remote arc discharge is confined within a remote arc volume adjacent to the magnetron target, the remote arc volume being defined by the surface of the target on one side and the electromagnetic barrier on all other sides; a remote arc discharge cathode hood arranged to extend over the remote arc discharge and across the short edge of the magnetron cathode; and a remote arc discharge anode hood; the vacuum coating and plasma treatment system further comprising a magnetic system arranged to create magnetic field lines which, in use, extend into and confine a plasma in front of the plasma assembly and the substrate. a magnetron target (Ts) having a target surface; a magnetron cathode with a long edge, a short edge and a magnetic pole, said magnetic pole being arranged to form, in use, a sputtering racetrack within the magnetron target (Ts) and an electromagnetic barrier; an anode (As) electrically connected to the magnetron cathode; a magnetron cathode power supply (Ps) connected to the magnetron cathode and to the anode; at least two remote arc discharge electrodes (44; 28); a remote arc discharge power supply connected between the at least two remote arc discharge electrodes (44; 28), and arranged to generate at least one remote arc discharge separate from the magnetron cathode and adjacent to the magnetron target, such that, in use, the remote arc discharge extends along a direction parallel to the long edge of the magnetron cathode, and such that, in use, the remote arc discharge is confined within a remote arc volume adjacent to the magnetron target, the remote arc volume being defined by the surface of the target on one side and the electromagnetic barrier on all other sides; a remote arc discharge cathode hood arranged to extend over the remote arc discharge and across the short edge of the magnetron cathode; and a remote arc discharge anode hood; the vacuum coating and plasma treatment system further comprising a magnetic system arranged to create magnetic field lines which, in use, extend into and confine a plasma in front of the plasma assembly and the substrate.
A method of joining an amorphous alloy material to a heterogeneous material, characterized by comprising steps of: placing a pre-formed piece made of the amorphous alloy material into a mold; heating the heterogeneous material to a predetermined temperature, and then casting the heterogeneous material into the mold to form a transition connection part, the transition connection part joining the amorphous alloy material to the heterogeneous material and having one of a fusion welded structure, a microstructure reinforcing connection structure and a composite connection structure, in which the fusion welded structure is formed by the amorphous alloy material and the heterogeneous material via fusion welding, the microstructure reinforcing connection structure is formed by a microstructure on a surface of the pre-formed piece and the heterogeneous material, and the composite connection structure comprises the fusion welded structure and the microstructure reinforcing connection structure; and cooling the amorphous alloy material and the heterogeneous material at a rate higher than a critical cooling rate of the amorphous alloy material to obtain a composite formed by the amorphous alloy material to the heterogeneous material joined via the transition connection part. placing a pre-formed piece made of the amorphous alloy material into a mold; heating the heterogeneous material to a predetermined temperature, and then casting the heterogeneous material into the mold to form a transition connection part, the transition connection part joining the amorphous alloy material to the heterogeneous material and having one of a fusion welded structure, a microstructure reinforcing connection structure and a composite connection structure, in which the fusion welded structure is formed by the amorphous alloy material and the heterogeneous material via fusion welding, the microstructure reinforcing connection structure is formed by a microstructure on a surface of the pre-formed piece and the heterogeneous material, and the composite connection structure comprises the fusion welded structure and the microstructure reinforcing connection structure; and cooling the amorphous alloy material and the heterogeneous material at a rate higher than a critical cooling rate of the amorphous alloy material to obtain a composite formed by the amorphous alloy material to the heterogeneous material joined via the transition connection part.
An apparatus for the production of fine fibers onto a collection media, comprising: a first electrode; a second electrode spaced from the first electrode, the second electrode including strand entrained upon at least two guides; an entrance region and an exit region spaced apart along a first path, wherein the collection media is adapted to be driven along the first path from the entrance region to the exit region in spaced relation from the second electrode; a drive unit adapted to drive the strand, along the at least two guides for movement along a second path that is transverse to the first path; a voltage source arranged to generate a voltage differential between the first and second electrodes (40, 42) for generating the spinning of fine fibers; wherein the strand is an endless chain of a plurality of discrete segments separated by gaps, wherein each segment typically provides at least one discrete spinning location wherein polymer fine fibers are electrospun during operation; and wherein the strand is an endless strand driven about an endless path, wherein the second path is a part of the endless path, the endless path further including a return path spaced from the second path, the endless strand being farther away from the first electrode along the return path than the second path. a first electrode; a second electrode spaced from the first electrode, the second electrode including strand entrained upon at least two guides; an entrance region and an exit region spaced apart along a first path, wherein the collection media is adapted to be driven along the first path from the entrance region to the exit region in spaced relation from the second electrode; a drive unit adapted to drive the strand, along the at least two guides for movement along a second path that is transverse to the first path; a voltage source arranged to generate a voltage differential between the first and second electrodes (40, 42) for generating the spinning of fine fibers; wherein the strand is an endless chain of a plurality of discrete segments separated by gaps, wherein each segment typically provides at least one discrete spinning location wherein polymer fine fibers are electrospun during operation; and wherein the strand is an endless strand driven about an endless path, wherein the second path is a part of the endless path, the endless path further including a return path spaced from the second path, the endless strand being farther away from the first electrode along the return path than the second path.
A processor comprising: a core (210a; 310a; 1610) to execute instructions; and a first storage to store state information of the core when the core is in a low power state, a core perimeter logic coupled to the core, the core perimeter logic including a fabric interface logic, wherein the first storage is comprised in the interface logic, wherein the core perimeter logic is to enable an inter-die interconnect coupled between the core and an uncore to be maintained in an active state during entry of the core into a low power state, wherein the fabric interface logic includes a snoop logic to receive a snoop request from a requester when the core (210a; 310a; 1610) is in the low power state and send a snoop response to the requester, wherein the core (210a; 310a; 1610) is to remain in the low power state, characterized in that the snoop response comprises a default snoop response to indicate that the core (210a; 310a; 1610) does not include data associated with the snoop request. a core (210a; 310a; 1610) to execute instructions; and a first storage to store state information of the core when the core is in a low power state, a core perimeter logic coupled to the core, the core perimeter logic including a fabric interface logic, wherein the first storage is comprised in the interface logic, wherein the core perimeter logic is to enable an inter-die interconnect coupled between the core and an uncore to be maintained in an active state during entry of the core into a low power state, wherein the fabric interface logic includes a snoop logic to receive a snoop request from a requester when the core (210a; 310a; 1610) is in the low power state and send a snoop response to the requester, wherein the core (210a; 310a; 1610) is to remain in the low power state, characterized in that the snoop response comprises a default snoop response to indicate that the core (210a; 310a; 1610) does not include data associated with the snoop request.
A vehicle surface with a cavity system, comprising: a cavity and a plurality of rods; the rods are positioned in the proximity of a leading edge of the cavity, the leading edge being relative to an actual or intended flow direction of a fluid over the cavity; the rods extending across at least a part of a width of the cavity in a perpendicular or oblique angle to the actual or intended flow direction. a cavity and a plurality of rods; the rods are positioned in the proximity of a leading edge of the cavity, the leading edge being relative to an actual or intended flow direction of a fluid over the cavity; the rods extending across at least a part of a width of the cavity in a perpendicular or oblique angle to the actual or intended flow direction.
A method for facilitating traffic load balancing among gateway routers providing an emulated switch in a fabric path switching network, the method comprising: receiving, at an access switch, a first network frame from an active gateway router in a group of gateway routers providing an emulated switch having an emulated switch ID and a media access control, MAC, address, wherein the frame includes the emulated switch ID; adding an entry to a MAC table on the access switch mapping the MAC address of the emulated switch to the emulated switch ID of the emulated switch; receiving, at the access switch, one or more link state messages from one or more respective standby gateway routers in the group, wherein each of the one or more link state messages includes the emulated switch ID; and for each link state message, adding an entry to a switch table indicating a link on the access switch over which the emulated switch is reachable, wherein the access switch is configured to load balance traffic to the emulated switch based on the MAC table and the switch table; receiving a second link state message from a given one of the gateway routers indicating that the given gateway router is withdrawing from the group; and removing the entry in the switch table indicating the emulated switch is reachable over the link corresponding to the given gateway router. receiving, at an access switch, a first network frame from an active gateway router in a group of gateway routers providing an emulated switch having an emulated switch ID and a media access control, MAC, address, wherein the frame includes the emulated switch ID; adding an entry to a MAC table on the access switch mapping the MAC address of the emulated switch to the emulated switch ID of the emulated switch; receiving, at the access switch, one or more link state messages from one or more respective standby gateway routers in the group, wherein each of the one or more link state messages includes the emulated switch ID; and for each link state message, adding an entry to a switch table indicating a link on the access switch over which the emulated switch is reachable, wherein the access switch is configured to load balance traffic to the emulated switch based on the MAC table and the switch table; receiving a second link state message from a given one of the gateway routers indicating that the given gateway router is withdrawing from the group; and removing the entry in the switch table indicating the emulated switch is reachable over the link corresponding to the given gateway router.