A compound selected from the group consisting of -3-(3-amino-1H-pyrazolo[3,4-b]pyridin-5-yl)-N-methyl-N-((1-methyl-1H-indol-2-yl)methyl)acrylamide; -N-Methyl-3-(3-methylamino-1H-pyrazolo[3,4-b]pyridin-5-yl)-N-(1-methyl-1H-indol-2-ylmethyl)-acrylamide; -3-(3-Dimethylamino-1H-pyrazolo[3,4-b]pyridin-5-yl)-N-methyl-N-(1-methyl-1H-indol-2-ylmethyl)-acrylamide; -N-Methyl-N-(1-methyl-1H-indol-2-ylmethyl)-3-(1-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-6-yl)-acrylamide; -3-(1-ethyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-6-yl)-N-methyl-N-((1-methyl-1 H-indol-2-yl)methyl)acry lamide; -N-(benzo[b]thiophen-2-ylmethyl)-3-(1-ethyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-6-yl)-N-methylacrylamide; -3-(3,3-dimethyl-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-methyl-N-((1-methyl-1H-indol-2-yl)methyl)acrylamide; -3-(3,3-diethyl-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-methyl-N-((1-methyl-1H-indol-2-yl)methyl)acrylamide; -N-(benzo[b]thiophen-2-ylmethyl)-3-(3,3-dimethyl-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-methylacrylamide; -3-(3,3-dimethyl-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)acrylamide; -3-(3,3-dimethyl-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-methyl-N-((3-methylbenzo[b]thiophen-2-yl)methyl)acrylamide; -N-methyl-N-((1-methyl-1H-indol-2-yl)methyl)-3-(2'-oxo-1',2'-dihydrospiro[cyclobutane-1,3'-pyrrolo[2,3-b]pyridine]-5'-yl)acrylamide; -3-(3,3-diethyl-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)acrylamide; -N-methyl-N-((3-methylbenzo[b]thiophen-2-yl)methyl)-3-(2'-oxo-1',2'-dihydrospiro-[cyclobutane-1,3'-pyrrolo[2,3-b]pyridine]-5'-yl)acrylamide; -N-methyl-N-((3-methylbenzo[b]thiophen-2-yl)methyl)-3-(2'-oxo-1',2'-dihydrospiro[cyclopentane-1,3'-pyrrolo[2,3-b]pyridine]-5'-yl)acrylamide; -N-methyl-N-((3-methylbenzo[b]thiophen-2-yl)methyl)-3-(2'-oxo-1',2'-dihydrospiro-[cyclohexane-1,3'-pyrrolo[2,3-b]pyridine]-5'-yl)acrylamide; -3-(3,3-diethyl-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-methyl-N-((3-methylbenzo[b]thiophen-2-yl)methyl)acrylamide; -N-methyl-N-((1-methyl-1H-indol-3-yl)methyl)-3-(2'-oxospiro[cyclobutane-1,3'-indoline]-5'-yl)acrylamide; -N-((3,5-dimethylbenzofuran-2-yl)methyl)-N-methyl-3-(2'-oxospiro[cyclobutane-1,3'-indoline]-5'-yl)acrylamide; -N-((1,2-dimethyl-1H-indol-3-yl)methyl)-N-methyl-3-(2'-oxo-1',2'-dihydrospiro-[cyclobutane-1,3'-pyrrolo[2,3-b]pyridine]-5'-yl)acrylamide; and -N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(2'-oxo-1',2'-dihydrospiro-[cyclobutane-1,3'-pyrrolo[2,3-b]pyridine]-5'-yl)acrylamide; or its tautomeric forms, stereoisomers, optical isomers, pharmaceutically acceptable salts, solvates or polymorphs thereof. -3-(3-amino-1H-pyrazolo[3,4-b]pyridin-5-yl)-N-methyl-N-((1-methyl-1H-indol-2-yl)methyl)acrylamide; -N-Methyl-3-(3-methylamino-1H-pyrazolo[3,4-b]pyridin-5-yl)-N-(1-methyl-1H-indol-2-ylmethyl)-acrylamide; -3-(3-Dimethylamino-1H-pyrazolo[3,4-b]pyridin-5-yl)-N-methyl-N-(1-methyl-1H-indol-2-ylmethyl)-acrylamide; -N-Methyl-N-(1-methyl-1H-indol-2-ylmethyl)-3-(1-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-6-yl)-acrylamide; -3-(1-ethyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-6-yl)-N-methyl-N-((1-methyl-1 H-indol-2-yl)methyl)acry lamide; -N-(benzo[b]thiophen-2-ylmethyl)-3-(1-ethyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-6-yl)-N-methylacrylamide; -3-(3,3-dimethyl-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-methyl-N-((1-methyl-1H-indol-2-yl)methyl)acrylamide; -3-(3,3-diethyl-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-methyl-N-((1-methyl-1H-indol-2-yl)methyl)acrylamide; -N-(benzo[b]thiophen-2-ylmethyl)-3-(3,3-dimethyl-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-methylacrylamide; -3-(3,3-dimethyl-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)acrylamide; -3-(3,3-dimethyl-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-methyl-N-((3-methylbenzo[b]thiophen-2-yl)methyl)acrylamide; -N-methyl-N-((1-methyl-1H-indol-2-yl)methyl)-3-(2'-oxo-1',2'-dihydrospiro[cyclobutane-1,3'-pyrrolo[2,3-b]pyridine]-5'-yl)acrylamide; -3-(3,3-diethyl-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)acrylamide; -N-methyl-N-((3-methylbenzo[b]thiophen-2-yl)methyl)-3-(2'-oxo-1',2'-dihydrospiro-[cyclobutane-1,3'-pyrrolo[2,3-b]pyridine]-5'-yl)acrylamide; -N-methyl-N-((3-methylbenzo[b]thiophen-2-yl)methyl)-3-(2'-oxo-1',2'-dihydrospiro[cyclopentane-1,3'-pyrrolo[2,3-b]pyridine]-5'-yl)acrylamide; -N-methyl-N-((3-methylbenzo[b]thiophen-2-yl)methyl)-3-(2'-oxo-1',2'-dihydrospiro-[cyclohexane-1,3'-pyrrolo[2,3-b]pyridine]-5'-yl)acrylamide; -3-(3,3-diethyl-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-N-methyl-N-((3-methylbenzo[b]thiophen-2-yl)methyl)acrylamide; -N-methyl-N-((1-methyl-1H-indol-3-yl)methyl)-3-(2'-oxospiro[cyclobutane-1,3'-indoline]-5'-yl)acrylamide; -N-((3,5-dimethylbenzofuran-2-yl)methyl)-N-methyl-3-(2'-oxospiro[cyclobutane-1,3'-indoline]-5'-yl)acrylamide; -N-((1,2-dimethyl-1H-indol-3-yl)methyl)-N-methyl-3-(2'-oxo-1',2'-dihydrospiro-[cyclobutane-1,3'-pyrrolo[2,3-b]pyridine]-5'-yl)acrylamide; and -N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(2'-oxo-1',2'-dihydrospiro-[cyclobutane-1,3'-pyrrolo[2,3-b]pyridine]-5'-yl)acrylamide; or its tautomeric forms, stereoisomers, optical isomers, pharmaceutically acceptable salts, solvates or polymorphs thereof.