A compound represented by formula, or a pharmaceutically acceptable salt, solvate, or stereoisomer thereof: wherein, Z 1, Z 2 are each independently N or CR 0; wherein, R 0 is selected from the group consisting of: H, halogen, C 1-10 alkyl, C 1-10 haloalkyl; R 1, R 2 are each independently H, halogen, C 1-10 alkyl, C 1-10 haloalkyl, C 1-10 alkoxy, C 3-8 cycloalkoxy; R 3 is H, halogen, C 2-10 alkenyl, C 1-10 alkyl, C 1-10 haloalkyl, C 1-10 alkoxy, C 3-8 cycloalkoxy, substituted or unsubstituted C 3-10 cycloalkyl, substituted or unsubstituted C 3-10 heterocyclic radical, substituted or unsubstituted C 6-10 aromatic ring, substituted or unsubstituted C 4-10 cycloalkenyl; R 4 is selected from the group consisting of: R 5 is H, hydroxy, CN, NO 2, halogen, C 1-10 alkyl, C 1-10 haloalkyl, C 1-10 alkoxy, C 3-10 cycloalkyl, C 3-8 cycloalkoxy, -CON(C 1-10 alkyl) 2, -NC C 1-10 alkyl, -C OC 1-10 alkyl, -OC C 1-10 alkyl, -COC 1-10 alkyl, -CO-phenyl, -SO 2 C 1-10 alkyl, -SO 2 -phenyl, -S C 1-10 alkyl, -S -phenyl, -N(C 1-10 alkyl) 2; wherein, said phenyl is unsubstituted or substituted with 1-3 substituents selected from the group consisting of: halogen, C 1-10 alkyl; R 6 and R 7 are each independently H, C 1-10 alkyl, substituted or unsubstituted C 6-10 aryl; wherein, said "substituted" means 1-6 hydrogen atoms on a ring atom are substituted with a substituent selected from the group consisting of: hydroxy, CN, NO 2, halogen, C 1-10 alkyl, C 1-10 haloalkyl, -CON(C 1-10 alkyl) 2, -C OC 1-10 alkyl, -OC C 1-10 alkyl, -COC 1-10 alkyl, -CO-phenyl, -SO 2 C 1-10 alkyl, -SO 2 -phenyl, -S C 1-10 alkyl, -S -phenyl, -N(C 1-10 alkyl) 2; wherein, said phenyl is unsubstituted or substituted with 1-3 substituents selected from the group consisting of: halogen, C 1-10 alkyl. Z 1, Z 2 are each independently N or CR 0; wherein, R 0 is selected from the group consisting of: H, halogen, C 1-10 alkyl, C 1-10 haloalkyl; R 1, R 2 are each independently H, halogen, C 1-10 alkyl, C 1-10 haloalkyl, C 1-10 alkoxy, C 3-8 cycloalkoxy; R 3 is H, halogen, C 2-10 alkenyl, C 1-10 alkyl, C 1-10 haloalkyl, C 1-10 alkoxy, C 3-8 cycloalkoxy, substituted or unsubstituted C 3-10 cycloalkyl, substituted or unsubstituted C 3-10 heterocyclic radical, substituted or unsubstituted C 6-10 aromatic ring, substituted or unsubstituted C 4-10 cycloalkenyl; R 4 is selected from the group consisting of: R 5 is H, hydroxy, CN, NO 2, halogen, C 1-10 alkyl, C 1-10 haloalkyl, C 1-10 alkoxy, C 3-10 cycloalkyl, C 3-8 cycloalkoxy, -CON(C 1-10 alkyl) 2, -NC C 1-10 alkyl, -C OC 1-10 alkyl, -OC C 1-10 alkyl, -COC 1-10 alkyl, -CO-phenyl, -SO 2 C 1-10 alkyl, -SO 2 -phenyl, -S C 1-10 alkyl, -S -phenyl, -N(C 1-10 alkyl) 2; wherein, said phenyl is unsubstituted or substituted with 1-3 substituents selected from the group consisting of: halogen, C 1-10 alkyl; R 6 and R 7 are each independently H, C 1-10 alkyl, substituted or unsubstituted C 6-10 aryl; wherein, said "substituted" means 1-6 hydrogen atoms on a ring atom are substituted with a substituent selected from the group consisting of: hydroxy, CN, NO 2, halogen, C 1-10 alkyl, C 1-10 haloalkyl, -CON(C 1-10 alkyl) 2, -C OC 1-10 alkyl, -OC C 1-10 alkyl, -COC 1-10 alkyl, -CO-phenyl, -SO 2 C 1-10 alkyl, -SO 2 -phenyl, -S C 1-10 alkyl, -S -phenyl, -N(C 1-10 alkyl) 2; wherein, said phenyl is unsubstituted or substituted with 1-3 substituents selected from the group consisting of: halogen, C 1-10 alkyl.