An aerosolization device, comprising: an aerosol chamber having a first end and a second end; an aerosol generator positioned at the first end of the aerosol chamber, wherein the aerosol generator is configured to aerosolize a volume of medicament into particles having a mass mean aerodynamic diameter (MMAD) of less than about 3 μm at a rate of at least 0.1 ml/min; a patient interface that is positioned proximate the second end of the aerosol chamber; and a respiratory adaptor that is configured to couple the aerosolization device with a respiration system and to divert a portion of airflow of the respiration system to the aerosol chamber via a fluid channel, wherein: the aerosol chamber is configured to mix the portion of the airflow with aerosolized medicament from the aerosol generator for subsequent delivery to a patient via the patient interface; characterized in that: the respiratory adaptor comprises a diversion mechanism that is configured to divert the portion of airflow from the respiration system into the aerosol chamber via the fluid channel; the diversion mechanism comprises at least one baffle (622, 626) that defines the fluid channel; and the at least one baffle (622, 626) is configured to divert the portion of airflow into the aerosol chamber via the fluid channel and to divert an additional portion of airflow from an inspiratory limb of the respiration system to an expiratory limb of the respiration system. an aerosol chamber having a first end and a second end; an aerosol generator positioned at the first end of the aerosol chamber, wherein the aerosol generator is configured to aerosolize a volume of medicament into particles having a mass mean aerodynamic diameter (MMAD) of less than about 3 μm at a rate of at least 0.1 ml/min; a patient interface that is positioned proximate the second end of the aerosol chamber; and a respiratory adaptor that is configured to couple the aerosolization device with a respiration system and to divert a portion of airflow of the respiration system to the aerosol chamber via a fluid channel, wherein: the aerosol chamber is configured to mix the portion of the airflow with aerosolized medicament from the aerosol generator for subsequent delivery to a patient via the patient interface; characterized in that: the respiratory adaptor comprises a diversion mechanism that is configured to divert the portion of airflow from the respiration system into the aerosol chamber via the fluid channel; the diversion mechanism comprises at least one baffle (622, 626) that defines the fluid channel; and the at least one baffle (622, 626) is configured to divert the portion of airflow into the aerosol chamber via the fluid channel and to divert an additional portion of airflow from an inspiratory limb of the respiration system to an expiratory limb of the respiration system. the aerosol chamber is configured to mix the portion of the airflow with aerosolized medicament from the aerosol generator for subsequent delivery to a patient via the patient interface; characterized in that: the respiratory adaptor comprises a diversion mechanism that is configured to divert the portion of airflow from the respiration system into the aerosol chamber via the fluid channel; the diversion mechanism comprises at least one baffle (622, 626) that defines the fluid channel; and the at least one baffle (622, 626) is configured to divert the portion of airflow into the aerosol chamber via the fluid channel and to divert an additional portion of airflow from an inspiratory limb of the respiration system to an expiratory limb of the respiration system. the respiratory adaptor comprises a diversion mechanism that is configured to divert the portion of airflow from the respiration system into the aerosol chamber via the fluid channel; the diversion mechanism comprises at least one baffle (622, 626) that defines the fluid channel; and the at least one baffle (622, 626) is configured to divert the portion of airflow into the aerosol chamber via the fluid channel and to divert an additional portion of airflow from an inspiratory limb of the respiration system to an expiratory limb of the respiration system.