A method of handling and processing tires in a tire production facility, the method comprising - a) positioning an uncured tire in a support for supporting the tire, where the support is provided with a through-going hole, and where said tire is positioned in the support so that the tire is lying with its centre opening centred or substantially centred with the through-going hole of the support, - b) moving the support with said tire in a conveyor system, where the conveyor system comprises one or more conveyor sections with a friction drive device towards each side of the one or more conveyor sections, where the friction drive device is provided for moving the support in a moving direction by friction between the friction drive device and the support, and where friction drive devices towards each side leave an open through-going space in a middle of the conveyor section, - c) stopping the support with said tire from moving in the moving direction at such a conveyor section provided with an applicator station with an applicator, - d) positioning the support with the tire relative to the applicator and so that an applicator head of the applicator is able to apply a substance on a surface (508, 806) of said tire, and where method step d) is provided by raising the applicator head up in said open through-going space and in an upward direction from below the conveyor section, and using said open through-going space and said through-going hole of the support, so as to enable positioning of the applicator head relative to the surface (508, 806) of the tire and for said applicator head to apply the substance on said surface (508, 806). - a) positioning an uncured tire in a support for supporting the tire, where the support is provided with a through-going hole, and where said tire is positioned in the support so that the tire is lying with its centre opening centred or substantially centred with the through-going hole of the support, - b) moving the support with said tire in a conveyor system, where the conveyor system comprises one or more conveyor sections with a friction drive device towards each side of the one or more conveyor sections, where the friction drive device is provided for moving the support in a moving direction by friction between the friction drive device and the support, and where friction drive devices towards each side leave an open through-going space in a middle of the conveyor section, - c) stopping the support with said tire from moving in the moving direction at such a conveyor section provided with an applicator station with an applicator, - d) positioning the support with the tire relative to the applicator and so that an applicator head of the applicator is able to apply a substance on a surface (508, 806) of said tire, and where method step d) is provided by raising the applicator head up in said open through-going space and in an upward direction from below the conveyor section, and using said open through-going space and said through-going hole of the support, so as to enable positioning of the applicator head relative to the surface (508, 806) of the tire and for said applicator head to apply the substance on said surface (508, 806).