A wound treatment apparatus comprising: a housing comprising an exterior wall enclosing a device interior; an oxygen supply connector panel coupled to the housing wall and including at least one oxygen supply fitting extending through the wall, the oxygen supply fitting configured to couple oxygen provided by an external oxygen source into the device interior;; a compressor pump disposed within the housing and configured for coupling to an external oxygen source and to an external wound dressing, the input side of the compressor pump connected in fluid communication with the oxygen supply fitting, the compressor pump further configured to deliver therapeutically effective levels of hyperbaric oxygen to a wound dressing during a positive pressure operational mode; a vacuum pump disposed within the housing and configured for coupling to an external wound dressing, the vacuum pump further configured to deliver therapeutically effective levels of negative pressure to a wound dressing during a negative pressure operational mode; an oxygen concentrator disposed within the housing and operatively coupled to the compressor pump, the oxygen concentrator effective to supply oxygen enriched air to the compressor pump during the positive pressure operational mode; a controller disposed within the housing and operatively connected to the compressor pump, to the vacuum pump, and to the oxygen concentrator; and a user interface functionally coupled to the controller; wherein the controller is responsive to commands entered at the user interface and is configured to selectively switch the apparatus between the positive pressure and negative pressure operational modes. a housing comprising an exterior wall enclosing a device interior; an oxygen supply connector panel coupled to the housing wall and including at least one oxygen supply fitting extending through the wall, the oxygen supply fitting configured to couple oxygen provided by an external oxygen source into the device interior;; a compressor pump disposed within the housing and configured for coupling to an external oxygen source and to an external wound dressing, the input side of the compressor pump connected in fluid communication with the oxygen supply fitting, the compressor pump further configured to deliver therapeutically effective levels of hyperbaric oxygen to a wound dressing during a positive pressure operational mode; a vacuum pump disposed within the housing and configured for coupling to an external wound dressing, the vacuum pump further configured to deliver therapeutically effective levels of negative pressure to a wound dressing during a negative pressure operational mode; an oxygen concentrator disposed within the housing and operatively coupled to the compressor pump, the oxygen concentrator effective to supply oxygen enriched air to the compressor pump during the positive pressure operational mode; a controller disposed within the housing and operatively connected to the compressor pump, to the vacuum pump, and to the oxygen concentrator; and a user interface functionally coupled to the controller; wherein the controller is responsive to commands entered at the user interface and is configured to selectively switch the apparatus between the positive pressure and negative pressure operational modes.