mhurhangee/ep-ind-claims huggingface dataset:
Brentuximab vedotin for use in treating a hematological or lymphoid cancer in a non-adult human subject, wherein the Brentuximab vedotin is administered at a dose of between: 32-78 mg/m 2, e.g.,:: 64-78 mg/m 2, e.g. between: 66-76, 68-74, 70-72, or 71.5 mg/m 2, e.g., every three weeks; or e.g.,: 43-53 mg/m 2, e.g. between: 45-51, 47-49, or 48 mg/m 2, e.g., every two weeks, or, e.g., 32-40 mg/m 2, e.g. between: 34-38, 35-37, or 36 mg/m 2, e.g. every two weeks.: 64-78 mg/m 2, e.g. between: 66-76, 68-74, 70-72, or 71.5 mg/m 2, e.g., every three weeks; or e.g.,: 43-53 mg/m 2, e.g. between: 45-51, 47-49, or 48 mg/m 2, e.g., every two weeks, or, e.g., 32-40 mg/m 2, e.g. between: 34-38, 35-37, or 36 mg/m 2, e.g. every two weeks.
A collagen composite for controlled release of active substances, characterized in that it comprises at least one layer of highly porous sponge and at least one nanofiber crosslinked collagen layer prepared by electrostatic spinning, wherein the highly porous sponge contains crosslinked type I collagen and has an open porosity in the range of 70 - 90% and a mean pore size 50 - 200 μm, wherein at least 50% of the pore volume has a pore size above 80 μm, and wherein the diameter of the fibers of the nanofiber layer is in the range of 100 - 350 nm.
A process for the preparation of a zeolitic material having a CHA framework structure comprising YO 2 and X 2 O 3, wherein the zeolitic material displays a Y: X molar ratio comprised in the range of from 1 to 10.5, wherein said process comprises the steps of providing a mixture comprising N,N-Dimethylpiperidinium hydroxide and further comprising one or more sources for YO 2 and one or more sources for X 2 O 3; crystallizing the mixture provided in; wherein Y is a tetravalent element, and X is a trivalent element, and wherein the molar ratio of N,N-Dimethylpiperidinium hydroxide to Y in the mixture provided in step and crystallized in step is equal to or greater than 0.25, wherein said molar ratio is preferably comprised in the range of from 0.25 to 5, more preferably of from 0.25 to 3, more preferably of from 0.25 to 2, more preferably of from 0.3 to 1.7, more preferably of from 0.4 to 1.5, more preferably of from 0.45 to 1.3, more preferably of from 0.5 to 1.2, and even more preferably of from 0.55 to 1.15, wherein the YO 2: X 2 O 3 molar ratio in the mixture provided in step is comprised in the range of from 5 to 300. providing a mixture comprising N,N-Dimethylpiperidinium hydroxide and further comprising one or more sources for YO 2 and one or more sources for X 2 O 3; crystallizing the mixture provided in;
A method for improving efficiency of a power converter; the power converter comprising a control logic and a switch coupled between the control logic, a power source (Vin) and a middle node which is for coupling an inductor; the control logic controlling on and off of the switch; the power converter supplying an inductor current to the inductor at the middle node to result in an output voltage (Vo) and a load current (iLoad); the method comprises: during an intermediate mode, by turning on and off the switch with the control logic, controlling the inductor current to ripple with peaks at a peak current threshold (I_peak) and valleys which vary as the load current (iLoad) varies, and determining to enter a heavy-load mode from the intermediate mode when an on-time for the switch to remain on is shorter than a predetermined on-time threshold; characterized in that the method further comprises: determining to enter the intermediate mode from the heavy-load mode when the peaks of the inductor current are lower than a mode-switching current threshold for a predetermined number of consecutive on-off cycles of the switch. during an intermediate mode, by turning on and off the switch with the control logic, controlling the inductor current to ripple with peaks at a peak current threshold (I_peak) and valleys which vary as the load current (iLoad) varies, and determining to enter a heavy-load mode from the intermediate mode when an on-time for the switch to remain on is shorter than a predetermined on-time threshold; characterized in that the method further comprises: determining to enter the intermediate mode from the heavy-load mode when the peaks of the inductor current are lower than a mode-switching current threshold for a predetermined number of consecutive on-off cycles of the switch.
A method for determining whether endometriosis of a subject is likely to progress to clear cell ovarian carcinoma, endometrioid carcinoma, endometrial carcinoma, or uterine carcinoma; for determining the prognosis for a subject suffering from clear cell ovarian carcinoma, endometrioid carcinoma, endometrial carcinoma, or uterine carcinoma; and/or for determining whether standard chemotherapeutic agents are likely to be effective in treating clear cell ovarian carcinoma, endometrioid carcinoma, endometrial carcinoma, or uterine carcinoma; the method comprising assaying a sample of the endometriosis or carcinoma for expression of BAF250a, wherein the absence of expression of BAF250a indicates a likelihood that the endometriosis will progress to clear cell ovarian carcinoma, endometrioid carcinoma, endometrial carcinoma, or uterine carcinoma, indicates a poor prognosis, or indicates that the standard chemotherapeutic agents are not likely to be effective.
A magnetic sensor device for sensing an external magnetic field, comprising a plurality of magnetic logic unit, MLU, cells, each MLU cell comprising a magnetic tunnel junction including a sense layer having a sense magnetization freely orientable in the external magnetic field; a storage layer having a storage magnetization; and a tunnel barrier layer between the sense layer and the storage layer; wherein,the magnetic sensor device further comprises a stress inducing device configured for applying an anisotropic mechanical stress on the magnetic tunnel junction such as to induce a stress-induced magnetic anisotropy (271, 272) on at least one of the sense layer and the storage layer; and in that the stress-induced magnetic anisotropy (271, 272) induced by the stress inducing device corresponds substantially to a net magnetic anisotropy (281, 282) of said at least one of the sense layer and the storage layer characterized in that the stress inducing device is further configured such that the applied anisotropic mechanical stress induces the stress-induced magnetic anisotropy (271, 272) in the sense and storage layers (21, 23), such that a direction of the sense stress-induced magnetic anisotropy of the sense layer differs from a direction of the storage stress-induced magnetic anisotropy of the storage layer.
An electromagnetic wave shielding film, comprising: a metal foam in the form of a film, and a polymer component on the surface of the metal foam and inside the metal foam, wherein 90% or more of the total pores in the metal foam has a pore size of 10 to 100 μm, wherein the metal foam has a porosity of 70% or so, wherein the ratio (T/MT) of the total thickness to the thickness of the metal foam is 1.14, wherein the metal foam has a thickness of 350 μm or so, wherein the metal foam has a skeleton comprising copper, and wherein the polymer component comprises a silicone resin. a metal foam in the form of a film, and a polymer component on the surface of the metal foam and inside the metal foam, wherein 90% or more of the total pores in the metal foam has a pore size of 10 to 100 μm, wherein the metal foam has a porosity of 70% or so, wherein the ratio (T/MT) of the total thickness to the thickness of the metal foam is 1.14, wherein the metal foam has a thickness of 350 μm or so, wherein the metal foam has a skeleton comprising copper, and wherein the polymer component comprises a silicone resin.
A package for flat packaging goods with a package rear side and a package front side connected thereto to form a packaging space surrounded by the package, wherein one side of one of the package rear side and package front side has as the tear-open side a tear-open zone which has a smaller surface area than the tear-open side, and in the extension plane of the tear-open side on at least two edges (30 or 32, at 36) extending in linearly independent directions adjoins packaging material of the tear-open side, and which in the unopened package state is separable from the adjoining packaging material of the tear-open side by the application of an external force at least in sections to form a package opening affecting the packaging space, wherein for this purpose the tear-open side is formed from film material at least in the tear-open zone, wherein the tear-open zone comprises a grip tab at its start, wherein a material weakening created by the formation of the grip tab, in particular piercing, of the tear-open side is separated from the packaging space in such a way that the integrity of the enclosure of the packaging space is not impaired, wherein the package front side and the package rear side are joined to one another by sealing in a non-detachable manner along a sealing edge surrounding the packaging space, characterized in that the tear-open side is detachably connected to the respective other side of one of package front side and package rear side along a detaching zone which is situated at least in sections between the grip tab and the packaging space behind the grip tab in the tear-open direction and extends at least over the entire width of the tear-open zone.
A distributed induction-controlled solar lighting system, comprising: solar lights comprising a first light and multiple second lights, the multiple second lights being in a communication connection with the first light, and the first light and the second lights each comprising a first sensor for monitoring a pedestrian or an animal passing through a sensing range of the lights in real time and a sub-controller controlling brightness of the lights; the first sensor being able to trigger the brightness of the first light and/or the second lights within a preset range to increase when sensing that a pedestrian or an animal passes by, characterized in that the distributed induction-controlled solar lighting system comprises an inductive switch spaced apart from the first light for triggering the brightness of the first light within its preset range to increase when sensing that a pedestrian or an animal passes by. solar lights comprising a first light and multiple second lights, the multiple second lights being in a communication connection with the first light, and the first light and the second lights each comprising a first sensor for monitoring a pedestrian or an animal passing through a sensing range of the lights in real time and a sub-controller controlling brightness of the lights; the first sensor being able to trigger the brightness of the first light and/or the second lights within a preset range to increase when sensing that a pedestrian or an animal passes by, characterized in that the distributed induction-controlled solar lighting system comprises an inductive switch spaced apart from the first light for triggering the brightness of the first light within its preset range to increase when sensing that a pedestrian or an animal passes by.
Luminaire - having a linear and elongated support profile for wall or ceiling installation, - having a linear and elongated device carrier on which at least one electrical consumer is arranged and which is fastened releasably to the support profile, - wherein the device carrier is formed by an extruded profile made from a light metal alloy or made from a light metal, - wherein the extruded profile has an outer latch contour facing outwards on its longitudinal sides respectively, said outer latch contour interacting with an inner latch contour which is complementary to this, is formed on the support profile and faces inwards, in order to fasten the device carrier to the support profile, characterised in that the extruded profile is additionally locked in place with the support profile by means of at least one retaining clip. - having a linear and elongated support profile for wall or ceiling installation, - having a linear and elongated device carrier on which at least one electrical consumer is arranged and which is fastened releasably to the support profile, - wherein the device carrier is formed by an extruded profile made from a light metal alloy or made from a light metal, - wherein the extruded profile has an outer latch contour facing outwards on its longitudinal sides respectively, said outer latch contour interacting with an inner latch contour which is complementary to this, is formed on the support profile and faces inwards, in order to fasten the device carrier to the support profile,
A plasticizer composition comprising: a terephthalate-based material; and a Citrate-based material, wherein a weight ratio of the terephthalate-based material to the Citrate-based material is in a range of 8:2 to 6:4, wherein the Citrate-based material is one in which an acetyl group is not included, and wherein the terephthalate-based material and the Citrate-based material are, respectively, (a) di(2-ethylhexyl)terephthalate (DEHTP or DOTP) and triisobutyl citrate (TiBC), or (b) diisononyl terephthalate (DINTP) and tributyl citrate, or (c) diisononyl terephthalate (DINTP) and triisobutyl citrate (TiBC). a terephthalate-based material; and a Citrate-based material, wherein a weight ratio of the terephthalate-based material to the Citrate-based material is in a range of 8:2 to 6:4, wherein the Citrate-based material is one in which an acetyl group is not included, and wherein the terephthalate-based material and the Citrate-based material are, respectively, (a) di(2-ethylhexyl)terephthalate (DEHTP or DOTP) and triisobutyl citrate (TiBC), or (b) diisononyl terephthalate (DINTP) and tributyl citrate, or (c) diisononyl terephthalate (DINTP) and triisobutyl citrate (TiBC). (a) di(2-ethylhexyl)terephthalate (DEHTP or DOTP) and triisobutyl citrate (TiBC), or (b) diisononyl terephthalate (DINTP) and tributyl citrate, or (c) diisononyl terephthalate (DINTP) and triisobutyl citrate (TiBC).
Camera system, comprising at least one camera; an at least partially transparent, three-dimensional, rotatable camera housing arranged in a field of view in front of the camera; and a drive device for the rotation of the camera enclosure, wherein the camera enclosure includes an at least partially transparent cylinder with a substantially circular cross-section, which has a flat or curved first end element at a first end, characterized in that the camera housing includes glass or is made of glass and the cylinder has at a second end a flat or curved second end element which is connected to the drive device.
An audio decoding device comprising: a demultiplexing circuit configured to demultiplex input encoded data into low-frequency encoded data, coefficient information for obtaining a coefficient set, and smoothing information relating to smoothing; a low-frequency decoding circuit configured to decode the low-frequency encoded data to generate a low-frequency signal; a subband dividing circuit configured to divide the low-frequency signal into a plurality of subbands to generate a low-frequency subband signal for each of the subbands; a feature amount calculating circuit configured to calculate a feature amount based on power within the low-frequency subband signals; a smoothing circuit configured to subject the feature amount to smoothing based on the smoothing information indicating a number of time frames to be used for the smoothing of the feature amount over time; a generating circuit configured to generate a high-frequency signal based on the coefficient set obtained from the coefficient information, the feature amount subjected to smoothing, and the low-frequency subband signals; and a synthesizing circuit configured to synthesize an output signal based on the low-frequency signal and the high-frequency signal and outputting the output signal. a demultiplexing circuit configured to demultiplex input encoded data into low-frequency encoded data, coefficient information for obtaining a coefficient set, and smoothing information relating to smoothing; a low-frequency decoding circuit configured to decode the low-frequency encoded data to generate a low-frequency signal; a subband dividing circuit configured to divide the low-frequency signal into a plurality of subbands to generate a low-frequency subband signal for each of the subbands; a feature amount calculating circuit configured to calculate a feature amount based on power within the low-frequency subband signals; a smoothing circuit configured to subject the feature amount to smoothing based on the smoothing information indicating a number of time frames to be used for the smoothing of the feature amount over time; a generating circuit configured to generate a high-frequency signal based on the coefficient set obtained from the coefficient information, the feature amount subjected to smoothing, and the low-frequency subband signals; and a synthesizing circuit configured to synthesize an output signal based on the low-frequency signal and the high-frequency signal and outputting the output signal.
Cutlery tray module for a dishwasher, said cutlery tray module comprising a bottom surface, adapted for substantially horizontal reception of cutlery items, said bottom surface comprising a plurality of cutlery holding elements, adapted to hold said cutlery items, and at least one elongated indentation, having a longitudinal extension in a direction D, wherein at least a number of said cutlery holding elements are arranged such that said cutlery holding elements are adapted to hold said cutlery items transversely, with respect to said direction D, and across said elongated indentation, characterized in that said bottom surface comprises at least a first supporting area, adapted to support said cutlery items, said supporting area extending in said direction D, along said indentation(s), and wherein said number of cutlery holding elements is arranged along said supporting area, and wherein said bottom surface comprises a second supporting area, and wherein said number of cutlery holding elements are arranged, along said first supporting area and said second supporting area, and wherein the first and second supporting areas 5, 6 are elevated with respect to the indentation 4, such that a space is provided between the cutlery items and the bottom surface 2 of the cutlery tray module 1, and wherein the first supporting area 5 is arranged along the opposite side of the indentation 4 with respect to the second supporting area 6.
An aft engine defining a central axis and configured to be mounted to an aircraft at an aft end of a fuselage of the aircraft, and the aircraft defines a mean line extending from a forward end to the aft end, the aft engine comprising: a fan rotatable about the central axis and including a plurality of fan blades; and a nacelle surrounding the plurality of fan blades of the fan and defining an inlet, the inlet defining a non-axis symmetric shape with respect to the central axis of the aft engine, wherein the nacelle is configured to extend substantially 360 degrees around the mean line of the aircraft; wherein the inlet includes a top half positioned above the central axis and a bottom half positioned below the central axis, wherein the top half of the inlet defines a top half inlet area, wherein the bottom half of the inlet defines a bottom half inlet area, and characterised in that the bottom half inlet area is greater than the top half inlet area. a fan rotatable about the central axis and including a plurality of fan blades; and a nacelle surrounding the plurality of fan blades of the fan and defining an inlet, the inlet defining a non-axis symmetric shape with respect to the central axis of the aft engine, wherein the nacelle is configured to extend substantially 360 degrees around the mean line of the aircraft; wherein the inlet includes a top half positioned above the central axis and a bottom half positioned below the central axis, wherein the top half of the inlet defines a top half inlet area, wherein the bottom half of the inlet defines a bottom half inlet area, and characterised in that the bottom half inlet area is greater than the top half inlet area.
An energy delivery device configured to be inserted into a bronchial passageway, comprising: a shaft having a proximal portion, a distal portion, and a plurality of lumens including a first lumen and a second lumen for fluid delivery or suctioning, the first lumen being a fluid delivery lumen configured to deliver fluid distally; a sheath; and an expandable energy transfer element disposed at the distal portion of the shaft, the energy transfer element adapted to apply energy to tissue, the energy transfer element including an RF electrode, the energy transfer element having a reduced profile for advancement, and an expanded profile to contact a surface of the bronchial passageway; wherein the shaft is configured to be slidably located within the sheath; and wherein an outer surface of the shaft or an inner surface of the sheath have a lubricious layer (138, 140). a shaft having a proximal portion, a distal portion, and a plurality of lumens including a first lumen and a second lumen for fluid delivery or suctioning, the first lumen being a fluid delivery lumen configured to deliver fluid distally; a sheath; and an expandable energy transfer element disposed at the distal portion of the shaft, the energy transfer element adapted to apply energy to tissue, the energy transfer element including an RF electrode, the energy transfer element having a reduced profile for advancement, and an expanded profile to contact a surface of the bronchial passageway; wherein the shaft is configured to be slidably located within the sheath; and wherein an outer surface of the shaft or an inner surface of the sheath have a lubricious layer (138, 140).
A composition for use in preventing or treating diseases caused by a decrease in telomerase activity or telomere length, or symptoms caused by cell loss and senescence, by increasing telomerase activity or extending a telomere length, wherein the composition comprises a pharmaceutically effective amount of one or more selected from the group consisting of a peptide comprising an amino acid sequence of SEQ ID NO: 1, a peptide having at least 80% sequence homology with SEQ ID NO: 1 or a fragment thereof, wherein the peptide having at least 80% sequence homology with SEQ ID NO:1 or a fragment thereof is effective in preventing and treating diseases induced by an abnormal decrease in telomerase activity or reduction and loss of a telomere length in cells, or a symptom caused by cellular senescence, and wherein the diseases or symptoms are one or more selected from a degenerative disease of the skeletal system, a degenerative disease of the muscular system, Bloom syndrome, Werner syndrome, and anemia. wherein the composition comprises a pharmaceutically effective amount of one or more selected from the group consisting of a peptide comprising an amino acid sequence of SEQ ID NO: 1, a peptide having at least 80% sequence homology with SEQ ID NO: 1 or a fragment thereof, wherein the peptide having at least 80% sequence homology with SEQ ID NO:1 or a fragment thereof is effective in preventing and treating diseases induced by an abnormal decrease in telomerase activity or reduction and loss of a telomere length in cells, or a symptom caused by cellular senescence, and wherein the diseases or symptoms are one or more selected from a degenerative disease of the skeletal system, a degenerative disease of the muscular system, Bloom syndrome, Werner syndrome, and anemia.