A laser irradiation apparatus comprising: a motion controlling unit for setting a guide path on a surface of an object; and a robot arm, mounted with an end-effector, for applying a laser to the surface of the object corresponding to the guide path, wherein the laser irradiation apparatus is configured to perform a laser irradiation which includes an acceleration section where a moving speed of the robot arm is gradually increased, a maintain section where the moving speed of the robot arm is constantly maintained and a reduction section where the moving speed of the robot arm is gradually decreased, so that: during the acceleration section, at least one of a fluence and a frequency of the laser is gradually increased in proportion to the moving speed of the robot arm, wherein the guide path is set within a region of interest on the surface of the object, and wherein the region of interest include a region of therapy and a region of normal, wherein the laser irradiation apparatus is configured to distinguish the region of therapy and the region of normal based on at least one of a color, contrast, contour and texture on the surface of the object, during the maintain section, the laser irradiation is turned on when passing through the region of therapy and the laser irradiation is turned off when passing through the region of normal, and during the reduction section, at least one of the fluence and the frequency of the laser is gradually decreased in proportion to the moving speed of the robot arm. a motion controlling unit for setting a guide path on a surface of an object; and a robot arm, mounted with an end-effector, for applying a laser to the surface of the object corresponding to the guide path, wherein the laser irradiation apparatus is configured to perform a laser irradiation which includes an acceleration section where a moving speed of the robot arm is gradually increased, a maintain section where the moving speed of the robot arm is constantly maintained and a reduction section where the moving speed of the robot arm is gradually decreased, so that: during the acceleration section, at least one of a fluence and a frequency of the laser is gradually increased in proportion to the moving speed of the robot arm, wherein the guide path is set within a region of interest on the surface of the object, and wherein the region of interest include a region of therapy and a region of normal, wherein the laser irradiation apparatus is configured to distinguish the region of therapy and the region of normal based on at least one of a color, contrast, contour and texture on the surface of the object, during the maintain section, the laser irradiation is turned on when passing through the region of therapy and the laser irradiation is turned off when passing through the region of normal, and during the reduction section, at least one of the fluence and the frequency of the laser is gradually decreased in proportion to the moving speed of the robot arm. during the acceleration section, at least one of a fluence and a frequency of the laser is gradually increased in proportion to the moving speed of the robot arm, wherein the guide path is set within a region of interest on the surface of the object, and wherein the region of interest include a region of therapy and a region of normal, wherein the laser irradiation apparatus is configured to distinguish the region of therapy and the region of normal based on at least one of a color, contrast, contour and texture on the surface of the object, during the maintain section, the laser irradiation is turned on when passing through the region of therapy and the laser irradiation is turned off when passing through the region of normal, and during the reduction section, at least one of the fluence and the frequency of the laser is gradually decreased in proportion to the moving speed of the robot arm.