mhurhangee/ep-ind-claims huggingface dataset:
A composition comprising a therapeutically effective amount of one or more bacteria for use in treating a cancer in a human subject in need thereof, wherein the composition is to be administered to the human subject and the one or more bacteria are selected from the group consisting of Oscillibacter valericigenes, Acetatifactor muris, Alistipes putredinis, Alistipes finegoldii, Clostridium clostridioforme, Lactobacillus animalis, Lactobacillus murinus, Bacteroides massiliensis, Bacteroides sartorii, Muribaculum intestinale, Parasutterella excrementihominis, Clostridium methylpentosum, and Bacteroides rodentium, wherein (i) the human subject is identified as having a mutation in the Neuroblastoma RAS (NRAS) gene and poor responsiveness to treatment with a Mitogen-activated protein kinase inhibitor prior to administration of the composition and wherein the composition is to be administered to the human subject in combination with a MEK inhibitor; or (ii) the human subject is identified as having a mutation in the Serine/threonine-protein kinase B-raf (BRAF) gene and poor responsiveness to treatment with a BRAF inhibitor prior to administration of the composition and wherein the composition is to be administered to the human subject in combination with a BRAF inhibitor, wherein the cancer is melanoma. (i) the human subject is identified as having a mutation in the Neuroblastoma RAS (NRAS) gene and poor responsiveness to treatment with a Mitogen-activated protein kinase inhibitor prior to administration of the composition and wherein the composition is to be administered to the human subject in combination with a MEK inhibitor; or (ii) the human subject is identified as having a mutation in the Serine/threonine-protein kinase B-raf (BRAF) gene and poor responsiveness to treatment with a BRAF inhibitor prior to administration of the composition and wherein the composition is to be administered to the human subject in combination with a BRAF inhibitor,
Method for producing a grained film or a grained, multi-ply film laminate with an upper film and at least one lower film or at least one polyolefin-based foam, the method comprising the following steps: forming a polyolefin recyclate with a melting point < 165 °C by (a) comminuting film wastes having a fraction of crosslinked polyolefins, where the films comprising the film wastes include a varnished polyolefin-based film, optionally as an upper film together with a compact polyolefin-based lower film or a polyolefin-based foam, (b) extruding the comminuted film wastes, (c) filtering the melted extrudate, preferably via a screen with a mesh size in the range from 40 to 100 μm, and i) forming a compound containing polymer constituents as follows: - 5% to 75% by weight of the polyolefin recyclate produced in (a) to (c), - 5% to 75% by weight of an ethylene polymer or a mixture of two or more ethylene polymers with a density < 0.97 g/cm 3, - 0% to 50% by weight of a polypropylene with a density < 0.92 g/cm 3, and ii) moulding the compound into a film, and optionally iii) joining the film produced in (ii) to a lower film or a polyolefin-based foam, the film being embossed following step (ii) or after optional step (iii) for applying a grain, and the grained film being subsequently radiation-crosslinked. (a) comminuting film wastes having a fraction of crosslinked polyolefins, where the films comprising the film wastes include a varnished polyolefin-based film, optionally as an upper film together with a compact polyolefin-based lower film or a polyolefin-based foam, (b) extruding the comminuted film wastes, (c) filtering the melted extrudate, preferably via a screen with a mesh size in the range from 40 to 100 μm, i) forming a compound containing polymer constituents as follows: - 5% to 75% by weight of the polyolefin recyclate produced in (a) to (c), - 5% to 75% by weight of an ethylene polymer or a mixture of two or more ethylene polymers with a density < 0.97 g/cm 3, - 0% to 50% by weight of a polypropylene with a density < 0.92 g/cm 3, and - 5% to 75% by weight of the polyolefin recyclate produced in (a) to (c), - 5% to 75% by weight of an ethylene polymer or a mixture of two or more ethylene polymers with a density < 0.97 g/cm 3, - 0% to 50% by weight of a polypropylene with a density < 0.92 g/cm 3, and ii) moulding the compound into a film, and optionally iii) joining the film produced in (ii) to a lower film or a polyolefin-based foam, the film being embossed following step (ii) or after optional step (iii) for applying a grain, and the grained film being subsequently radiation-crosslinked.
A method carried out in a base station (700, 800) for synchronization in a wireless system, the method comprising: transmitting a physical broadcast channel, PBCH, including one or more bits, characterized in that the one or more bits indicate additional system information if a frequency of the wireless system is within a frequency range up to a predefined frequency and otherwise indicate a location of a slot group comprising at least one synchronization signal block in a synchronization signal burst set including said slot group.
Fitness equipment system connectable to a computer system, the fitness equipment system comprising a training mechanism to be operated by a user of the fitness equipment system for training purposes, at least one sensor assigned to the training mechanism for measuring a variable related to a physical work performed by the user when operating the training mechanism, the sensor generating a sensor signal, and an input-output unit for generating an output signal based on the sensor signal, characterized in that the input-output unit is configured to generate the output signal as an output signal of a standard computer system input device selected from the group consisting of a standard computer system keyboard, a standard computer system mouse, a standard computer system touchpad and a standard computer system trackpad such that the fitness equipment system is connectable to the computer system without the need to install a special device driver, which is not already installed on the computer system like for example a standard computer system keyboard device driver, and is detected by the computer system as a standard computer system input device, wherein the fitness equipment system comprises a data processing and mapping unit for converting the sensor signal into one or several of a multitude of input possibilities of the standard computer system input device, the data processing and mapping unit being part of the input-output unit or provided as a separate unit receiving the sensor signal and communicating with the input-output unit.
A local dimming boost up method for liquid crystal displays comprising the steps of; - Calculating a histogram of intensity map of an image which is displayed on the display, - Calculating dimming or boosting backlight driving values per each locally controllable backlight region according to said histogram of intensity map such that the regions determined to be bright are boosted and the regions determined to be dark are dimmed; characterized by, - Extracting a depth map of said image, wherein said depth map gives true information about the significance levels of the objects on an image in terms of human perception; - Calculating a histogram of said depth map for each locally controllable backlight regions of said display and according to the result determining driving values per region such that the driving values are boosted in regions presenting objects with higher significance; - Evaluating the driving values per region calculated according to the histogram of intensity map with the driving values per region calculated according to the histogram of the depth map to determine the final driving values per each locally controllable backlight region. - Calculating a histogram of intensity map of an image which is displayed on the display, - Calculating dimming or boosting backlight driving values per each locally controllable backlight region according to said histogram of intensity map such that the regions determined to be bright are boosted and the regions determined to be dark are dimmed; characterized by, - Extracting a depth map of said image, wherein said depth map gives true information about the significance levels of the objects on an image in terms of human perception; - Calculating a histogram of said depth map for each locally controllable backlight regions of said display and according to the result determining driving values per region such that the driving values are boosted in regions presenting objects with higher significance; - Evaluating the driving values per region calculated according to the histogram of intensity map with the driving values per region calculated according to the histogram of the depth map to determine the final driving values per each locally controllable backlight region.
An atomizing assembly structure, comprising an atomizing sleeve, a threaded sleeve and an atomizing core, the atomizing sleeve having a lower end fixed to the threaded sleeve, the atomizing assembly structure further comprising a tobacco liquid valve and a top cap, wherein the atomizing core is arranged inside the tobacco liquid valve, the atomizing core and the tobacco liquid valve are in pluggable connection, the tobacco liquid valve has an upper end connected to the top cap through threads, and the top cap covers and seals the atomizing sleeve, characterized in that the atomizing core comprises a head end of the atomizing core and a tail end of the atomizing core, and the head end and the tail end of the atomizing core are fixed together through threaded connection.
Support suitable for securing a sensor to a structure, said support comprising a damping member suitable, in use, for insulating the sensor from vibrations propagated in said structure, the support being a single-piece part with the damping member, the support is provided with an electrical link allowing the sensor to be linked to the electrical ground, characterized in that the damping member is arranged in a frame and adapted, in use, to surround the sensor; the damping member and the frame are entirely made of a single piece.
An organic light emitting diode, comprising: a first electrode; a second electrode facing the first electrode; and a first emitting material layer between the first and second electrodes (118, 128); characterized in that the organic light emitting diode further comprises: a second emitting material layer (130c") between the first emitting material layer and the second electrode and including a base material and an electron injection material, wherein the second emitting material layer (130c") physically contacts the second electrode. wherein the base material is a host material of the first emitting material layer, and wherein the electron injection material has a first density in a lower portion, which is adjacent to the first emitting material layer, of the second emitting material layer (130c"), and a second density, which is larger than the first density, in an upper portion, which is adjacent to the second electrode, of the second emitting material layer (130c"). a first electrode; a second electrode facing the first electrode; and a first emitting material layer between the first and second electrodes (118, 128); characterized in that the organic light emitting diode further comprises: a second emitting material layer (130c") between the first emitting material layer and the second electrode and including a base material and an electron injection material, wherein the second emitting material layer (130c") physically contacts the second electrode. wherein the base material is a host material of the first emitting material layer, and wherein the electron injection material has a first density in a lower portion, which is adjacent to the first emitting material layer, of the second emitting material layer (130c"), and a second density, which is larger than the first density, in an upper portion, which is adjacent to the second electrode, of the second emitting material layer (130c"). a second emitting material layer (130c") between the first emitting material layer and the second electrode and including a base material and an electron injection material, wherein the second emitting material layer (130c") physically contacts the second electrode. wherein the base material is a host material of the first emitting material layer, and wherein the electron injection material has a first density in a lower portion, which is adjacent to the first emitting material layer, of the second emitting material layer (130c"), and a second density, which is larger than the first density, in an upper portion, which is adjacent to the second electrode, of the second emitting material layer (130c").
A drive mechanism for an injection device for setting and dispensing of a dose of a medicament, the drive mechanism comprising: - an inner body fixable inside a housing of the injection device, the inner body comprising an elongated shaft extending in an axial direction (z), wherein the elongated shaft comprises an outer thread on an outer circumference, - a tubular-shaped display member having an inner thread engaged with the outer thread of the inner body, and - a dose member (70; 270) axially displaceable relative to at least one of the inner body and the display member between a dose setting position and a dose dispensing position, characterized in that - the elongated shaft comprises a blocking structure on the outer circumference, and - a blocking ring (180; 280; 380) axially engageable with the dose member (70; 270) is rotationally fixed to the display member and comprises at least one blocking element (182, 282; 382) to axially engage with the blocking structure for blocking an axial displacement of the dose member from the dose setting position towards the dose dispensing position. - an inner body fixable inside a housing of the injection device, the inner body comprising an elongated shaft extending in an axial direction (z), wherein the elongated shaft comprises an outer thread on an outer circumference, - a tubular-shaped display member having an inner thread engaged with the outer thread of the inner body, and - a dose member (70; 270) axially displaceable relative to at least one of the inner body and the display member between a dose setting position and a dose dispensing position, characterized in that - the elongated shaft comprises a blocking structure on the outer circumference, and - a blocking ring (180; 280; 380) axially engageable with the dose member (70; 270) is rotationally fixed to the display member and comprises at least one blocking element (182, 282; 382) to axially engage with the blocking structure for blocking an axial displacement of the dose member from the dose setting position towards the dose dispensing position.
A polysaccharide-polyamine copolymer having an amino functionality which will provide a protonatable copolymeric material having a three-dimensional structure with cationic sites through protonation, the polysaccharide-polyamine copolymer comprising: a selectively oxidized polysaccharide having a 2,3-dialdehyde moiety and having oxidized glucose units of at least 50%; and amino polymers which provide an amino functionality, the amino polymers cross linking the oxidized polysaccharides to provide a particulate polysaccharide-polyamine copolymer having an amino functionality which when protonated will provide the cationic copolymeric material with a nitrogen content of at least 12.3 wt.%, both the polysaccharide-polyamine copolymer and cationic copolymeric material being water insoluble. a selectively oxidized polysaccharide having a 2,3-dialdehyde moiety and having oxidized glucose units of at least 50%; and amino polymers which provide an amino functionality, the amino polymers cross linking the oxidized polysaccharides to provide a particulate polysaccharide-polyamine copolymer having an amino functionality which when protonated will provide the cationic copolymeric material with a nitrogen content of at least 12.3 wt.%, both the polysaccharide-polyamine copolymer and cationic copolymeric material being water insoluble.
A combination electronic article surveillance/radio frequency identification ("EAS/RFID") device comprising: a semiconductor device having an EAS circuit and an RFID circuit; an antenna circuit in electrical communication with the semiconductor device; and a capacitor, the capacitor including an insulation layer, wherein application of a predetermined voltage to the capacitor results in electrical breakdown of the insulation layer resulting in permanent deactivation of the EAS/RFID device, whereby the capacitor is a non-linear MOS capacitor and is part of the antenna circuit or part of the semiconductor device, characterized in that the MOS capacitor operates irreversibly as a linear capacitor with a lower capacitance value after breakdown. a semiconductor device having an EAS circuit and an RFID circuit; an antenna circuit in electrical communication with the semiconductor device; and a capacitor, the capacitor including an insulation layer, wherein application of a predetermined voltage to the capacitor results in electrical breakdown of the insulation layer resulting in permanent deactivation of the EAS/RFID device, whereby the capacitor is a non-linear MOS capacitor and is part of the antenna circuit or part of the semiconductor device, characterized in that the MOS capacitor operates irreversibly as a linear capacitor with a lower capacitance value after breakdown.
A spherical boron nitride fine particle, characterized by having an average particle diameter of 0.01 to 1.0 μm, an orientation index of 1 to 15, the orientation index being represented by a ratio (I 002 /I 100) between the diffraction line intensity I 002 of the plane and the diffraction line intensity I 100 of the plane as measured by powder X-ray diffractometry, a boron nitride purity of 98.0% by mass or greater, and an average circularity of 0.80 or greater.
Adapter piece for assembly of weapon accessories on a hand gun having a basebody which contains assembly elements for releasable attachment of the weapon accessories, wherein an attachment element for releasable attachment of the base body to a front stock of the hand gun is arranged on the base body, characterised in that the attachment element contains an attachment pin which can be inserted into an opening on the front side of the front stock and in that a ball ratchet mechanism having spring-loaded ratchet balls for locked mounting of the adapter piece on the front stock is arranged on the attachment element.
A composition comprising: (a) an ethylene/α-olefin random copolymer having density of 0.890 g/cm 3 or less, a melting point (Tm) of 100° C or less, determined from differential scanning calorimetry as described in the description, and a melt index (I 2) from 0.2 g/10 min to 8.0 g/10 min; measured in accordance with ASTM D1238-10, under conditions 190° C and 2.16 kg of load; (b) a styrenic block copolymer comprising from greater than 1 wt% to less than 50 wt% units of styrene; (c) a tackifier; and (d) an oil, wherein the composition exhibits an overall melt index of the composition of from 2 g/10 min to 15 g/10 min. (a) an ethylene/α-olefin random copolymer having density of 0.890 g/cm 3 or less, a melting point (Tm) of 100° C or less, determined from differential scanning calorimetry as described in the description, and a melt index (I 2) from 0.2 g/10 min to 8.0 g/10 min; measured in accordance with ASTM D1238-10, under conditions 190° C and 2.16 kg of load; (b) a styrenic block copolymer comprising from greater than 1 wt% to less than 50 wt% units of styrene; (c) a tackifier; and (d) an oil,
An electrostatic discharge protected device for conducting a fluid, in particular a non-polar fluid, through at least one lumen, wherein the device comprises: a tubing having a hollow interior defining the at least one lumen; wherein the tubing comprises an electrically conductive section configured for conducting electric charge, generated within the at least one lumen when the fluid flows through the at least one lumen, away from the at least one lumen, characterized in that the tubing comprises a chemically inert section against the fluid configured to suppress that the fluid dissolves any components out of the chemically inert section, the chemically inert section delimiting the entire lumen and forming an intermediate structure separating the at least one lumen from the electrically conductive section for preventing direct contact between the fluid and the electrically conductive section, and wherein the tubing comprises an exterior annular segment configured as the electrically conductive section, the chemically inert section being configured in terms of dimension and/or electric conductivity for electrically conducting the generated electric charge from the at least one lumen through the intermediate structure and towards the electrically conductive section. a tubing having a hollow interior defining the at least one lumen; wherein the tubing comprises an electrically conductive section configured for conducting electric charge, generated within the at least one lumen when the fluid flows through the at least one lumen, away from the at least one lumen, characterized in that the tubing comprises a chemically inert section against the fluid configured to suppress that the fluid dissolves any components out of the chemically inert section, the chemically inert section delimiting the entire lumen and forming an intermediate structure separating the at least one lumen from the electrically conductive section for preventing direct contact between the fluid and the electrically conductive section, and wherein the tubing comprises an exterior annular segment configured as the electrically conductive section, the chemically inert section being configured in terms of dimension and/or electric conductivity for electrically conducting the generated electric charge from the at least one lumen through the intermediate structure and towards the electrically conductive section.
A permanent concrete formwork for the manufacture of a metal-concrete composite structure, said formwork comprising: • two walls (20, 30) each formed of at least one metal plate, said walls (20, 30) being parallel, located facing each other and spaced apart from each other so as to delimit an internal volume of the formwork; • struts connecting the two walls (20, 30) and securing said two walls (20, 30) together, the struts passing right through said two walls (20, 30) and thereby protruding from each side of the formwork; • bars located on each of the walls (20, 30) and protruding in the internal volume of the formwork, each metal plate is secured to the opposite metal plate by at least three struts, a first strut being located at a first end of the metal plate, a second strut being located at a second end opposite said first end, and a third strut being located in a central region located between said first end and said second end, and the struts comprise threaded ends, the struts being secured to the metal plate by bolting, characterized in that the walls (20, 30) comprise two metal plates placed end-to-end, said formwork further comprising an assembly rod only deposited on the struts and/or on the bars, said assembly rod comprising a protrusion at each of its ends and being placed inside the internal volume of the formwork facing the connection between the two metal plates. • two walls (20, 30) each formed of at least one metal plate, said walls (20, 30) being parallel, located facing each other and spaced apart from each other so as to delimit an internal volume of the formwork; • struts connecting the two walls (20, 30) and securing said two walls (20, 30) together, the struts passing right through said two walls (20, 30) and thereby protruding from each side of the formwork; • bars located on each of the walls (20, 30) and protruding in the internal volume of the formwork,