mhurhangee/ep-ind-claims huggingface dataset:
A gait motion assisting device comprising an actuator for imparting assisting force to a gait motion of a user; a thigh orientation detecting means for detecting a hip joint angle-related signal relating to a hip joint angle that is a forward and backward swing angle of the user's thigh at each sampling timing; a thigh phase angle calculating means for calculating a thigh phase angle at one sampling timing k; an assisting torque calculating means having an output pattern data directly or indirectly defining a relationship between the thigh phase angle and a torque value that should be output by the actuator, wherein the assisting torque calculating means applies the thigh phase angle calculated by the thigh phase angle calculating means to the output pattern data to calculate a torque value that should be output at said one sampling timing k; and an operational control means responsible for operational control of the actuator so as to output assisting force having the torque value calculated by the assisting torque calculating means, wherein the thigh phase angle calculating means: replicates movement of the user's leg including a thigh and a lower leg around a hip joint in gait motion by pendulum movement of a rod-like rigid body having a predetermined length 1, wherein a distal end part of the rod-like rigid body has a material point having a predetermined mass m and a proximal end part of the rod-like rigid body serves as a swing center, estimates the hip joint angle and a hip joint angular velocity approximately calculated based on an equation of motion in a direction tangential to a circle drawn along a swing trajectory of the material point by a state estimator using the angle-related signal received from the thigh orientation detecting means at the sampling timing k as an observation, and calculates the thigh phase angle at the sampling timing k using an estimated hip joint angle and an estimated hip joint angular velocity. replicates movement of the user's leg including a thigh and a lower leg around a hip joint in gait motion by pendulum movement of a rod-like rigid body having a predetermined length 1, wherein a distal end part of the rod-like rigid body has a material point having a predetermined mass m and a proximal end part of the rod-like rigid body serves as a swing center, estimates the hip joint angle and a hip joint angular velocity approximately calculated based on an equation of motion in a direction tangential to a circle drawn along a swing trajectory of the material point by a state estimator using the angle-related signal received from the thigh orientation detecting means at the sampling timing k as an observation, and calculates the thigh phase angle at the sampling timing k using an estimated hip joint angle and an estimated hip joint angular velocity.
A method of making -3 -(4- {[2-(2-methyl-1H-indol-3-yl)-ethylamino]-methyl]-phenyl)-acrylic acid methyl ester hydrochloride salt comprising the steps of: (a) combining 2-methyltryptamine and -3-(4-formyl-phenyl)-acrylic acid methyl ester to form an admixture; (b) stirring the admixture for a time and at a temperature sufficient to form an imine intermediate; and (c) reducing the imine intermediate to form the -3-(4-{[2-(2-methyl-1H-indol-3-yl)-ethylamino]-methyl]-phenyl)-acrylic acid methyl ester hydrochloride salt; wherein step (c) comprises the sub-steps of: cooling the admixture; adding sodium borohydride to the admixture; and combining the admixture with hydrochloric acid to precipitate the -3-(4-{[2-(2-methyl-1H-indol-3-yl)-ethylamino]-methyl]-phenyl)-acrylic acid methyl ester hydrochloride salt. (a) combining 2-methyltryptamine and -3-(4-formyl-phenyl)-acrylic acid methyl ester to form an admixture; (b) stirring the admixture for a time and at a temperature sufficient to form an imine intermediate; and (c) reducing the imine intermediate to form the -3-(4-{[2-(2-methyl-1H-indol-3-yl)-ethylamino]-methyl]-phenyl)-acrylic acid methyl ester hydrochloride salt; wherein step (c) comprises the sub-steps of: cooling the admixture; adding sodium borohydride to the admixture; and combining the admixture with hydrochloric acid to precipitate the -3-(4-{[2-(2-methyl-1H-indol-3-yl)-ethylamino]-methyl]-phenyl)-acrylic acid methyl ester hydrochloride salt. cooling the admixture; adding sodium borohydride to the admixture; and combining the admixture with hydrochloric acid to precipitate the -3-(4-{[2-(2-methyl-1H-indol-3-yl)-ethylamino]-methyl]-phenyl)-acrylic acid methyl ester hydrochloride salt.
A charging member, comprising: a substrate; an elastic layer; and a surface layer, wherein: the surface layer comprises a high-molecular compound having an Si-O-Hf linkage; and the high-molecular compound has a constitutional unit represented by the following formula and a constitutional unit represented by the following formula: [Chemical Formula 27] Formula HfO 4/2 where, in the formula, R 1 and R 2 each independently represent any of structures represented by the formulae to: where, in the formulae to, R 3 to R 7, R 10 to R 14, R 19, R 20, R 25 and R 26 each independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atom(s), a hydroxyl group, a carboxyl group or an amino group; R 8, R 9, R 15 to R 18, R 23, R 24 and R 29 to R 32 each independently represent a hydrogen atom or an alkyl group having 1 to 4 carbon atom(s); R 21, R 22, R 27 and R 28 each independently represent a hydrogen atom, an alkoxyl group having 1 to 4 carbon atom(s) or an alkyl group having 1 to 4 carbon atom(s); n, m, I, q, s and t each independently represent an integer of 1 to 8, p and r each independently represent an integer of 4 to 12, and x and y each independently represent 0 or 1; and an asterisk * represents the position of bonding with the silicon atom in the formula and a double asterisk ** represents the position of bonding with the oxygen atom in the formula, and wherein the surface layer has an elastic modulus of from 2.0 GPa or more to 35.0 GPa or less. a substrate; an elastic layer; and a surface layer, the surface layer comprises a high-molecular compound having an Si-O-Hf linkage; and the high-molecular compound has a constitutional unit represented by the following formula and a constitutional unit represented by the following formula: [Chemical Formula 27] Formula HfO 4/2 where, in the formula, R 1 and R 2 each independently represent any of structures represented by the formulae to: where, in the formulae to, R 3 to R 7, R 10 to R 14, R 19, R 20, R 25 and R 26 each independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atom(s), a hydroxyl group, a carboxyl group or an amino group; R 8, R 9, R 15 to R 18, R 23, R 24 and R 29 to R 32 each independently represent a hydrogen atom or an alkyl group having 1 to 4 carbon atom(s); R 21, R 22, R 27 and R 28 each independently represent a hydrogen atom, an alkoxyl group having 1 to 4 carbon atom(s) or an alkyl group having 1 to 4 carbon atom(s); n, m, I, q, s and t each independently represent an integer of 1 to 8, p and r each independently represent an integer of 4 to 12, and x and y each independently represent 0 or 1; and an asterisk * represents the position of bonding with the silicon atom in the formula and a double asterisk ** represents the position of bonding with the oxygen atom in the formula, and wherein the surface layer has an elastic modulus of from 2.0 GPa or more to 35.0 GPa or less.
A method of controlling a washing machine including a full-touch Liquid Crystal Display to perform communication over a network, the method comprising the steps of: selecting a wash program through user touch input; displaying real-time weather information by performing communication over the network; characterized by determining whether the selected wash program suits the real-time weather information; performing the selected wash program if the selected wash program suits the real-time weather information; recommending a wash program according to the real-time weather information if the selected wash program does not suit the real-time weather information; and displaying basic wash information and energy usage of the recommended wash program and the message recommending that the selected wash program be changed. selecting a wash program through user touch input; displaying real-time weather information by performing communication over the network; characterized by determining whether the selected wash program suits the real-time weather information; performing the selected wash program if the selected wash program suits the real-time weather information; recommending a wash program according to the real-time weather information if the selected wash program does not suit the real-time weather information; and displaying basic wash information and energy usage of the recommended wash program and the message recommending that the selected wash program be changed.
A compound of general formula below: wherein: V-U is a carbon-carbon single bond and Y is a hydroxyl group or a hydrogen, or V-U is a C=C ethylenic bond; X is chosen from: an oxygen; an N-O R 5 group, R 5 then being chosen from: a hydrogen; a C 1 -C 6 alkyl group optionally having unsaturations on the chain; a (C 1 -C 6)CO 2 R 6 group with R 6 possibly being a hydrogen or a C 1 -C 6 group; a (C 1 -C 6)O R 7 group, R 7 being an aromatic or heteroaromatic ring optionally monosubstituted or polysubstituted with an alkyl or alkoxyl group, CF 3, Cl; a (C 1 -C 6)N R 8 R 9 group, R 8 and R 9 being C 1 -C 6 groups, or (C 1 -C 6)N(C 1 -C 6) groups or (C 1 -C 6)N(C 1 -C 6)O R 6 groups with R 6 as defined above, N R 8 R 9 can also be a heterocycle; and wherein: • Q is a carbonyl group; with R 1 being chosen from: a (C 1 -C 6) W (C 1 -C 6) group; a (C 1 -C 6) W (C 1 -C 6) W (C 1 -C 6) group; a (C 1 -C 6) W (C 1 -C 6)CO 2 (C 1 -C 6) group; a (C 1 -C 6) A group, A representing a heterocycle optionally substituted with a group of the type OH, OMe, (C 1 -C 6), N(C 1 -C 6) or CO 2 (C 1 -C 6); a CH 2 Br group; W being a heteroatom chosen from N, O and S; the compound being in the form of an enantiomer, a diastereoisomer, a hydrate, a solvate, a tautomer, a racemic mixture or a pharmaceutically acceptable salt. V-U is a carbon-carbon single bond and Y is a hydroxyl group or a hydrogen, or V-U is a C=C ethylenic bond; X is chosen from: an oxygen; an N-O R 5 group, R 5 then being chosen from: a hydrogen; a C 1 -C 6 alkyl group optionally having unsaturations on the chain; a (C 1 -C 6)CO 2 R 6 group with R 6 possibly being a hydrogen or a C 1 -C 6 group; a (C 1 -C 6)O R 7 group, R 7 being an aromatic or heteroaromatic ring optionally monosubstituted or polysubstituted with an alkyl or alkoxyl group, CF 3, Cl; a (C 1 -C 6)N R 8 R 9 group, R 8 and R 9 being C 1 -C 6 groups, or (C 1 -C 6)N(C 1 -C 6) groups or (C 1 -C 6)N(C 1 -C 6)O R 6 groups with R 6 as defined above, N R 8 R 9 can also be a heterocycle; and wherein: • Q is a carbonyl group; with R 1 being chosen from: a (C 1 -C 6) W (C 1 -C 6) group; a (C 1 -C 6) W (C 1 -C 6) W (C 1 -C 6) group; a (C 1 -C 6) W (C 1 -C 6)CO 2 (C 1 -C 6) group; a (C 1 -C 6) A group, A representing a heterocycle optionally substituted with a group of the type OH, OMe, (C 1 -C 6), N(C 1 -C 6) or CO 2 (C 1 -C 6); a CH 2 Br group; W being a heteroatom chosen from N, O and S; • Q is a carbonyl group; with R 1 being chosen from: a (C 1 -C 6) W (C 1 -C 6) group; a (C 1 -C 6) W (C 1 -C 6) W (C 1 -C 6) group; a (C 1 -C 6) W (C 1 -C 6)CO 2 (C 1 -C 6) group; a (C 1 -C 6) A group, A representing a heterocycle optionally substituted with a group of the type OH, OMe, (C 1 -C 6), N(C 1 -C 6) or CO 2 (C 1 -C 6); a CH 2 Br group; W being a heteroatom chosen from N, O and S; with R 1 being chosen from: a (C 1 -C 6) W (C 1 -C 6) group; a (C 1 -C 6) W (C 1 -C 6) W (C 1 -C 6) group; a (C 1 -C 6) W (C 1 -C 6)CO 2 (C 1 -C 6) group; a (C 1 -C 6) A group, A representing a heterocycle optionally substituted with a group of the type OH, OMe, (C 1 -C 6), N(C 1 -C 6) or CO 2 (C 1 -C 6); a CH 2 Br group; W being a heteroatom chosen from N, O and S;
A stackable structural reactor comprising: a) an outer tube, b) multiple catalyst support components arranged on a center support, the catalyst support components having an outer circumferential face, the catalyst support components being positioned in the outer tube; c) a wire standoff, a portion of the wire standoff being positioned between the outer tube and the catalyst support components to prevent the catalyst support components from contacting the outer tube, and d) a washer being positioned in the outer tube, wherein (i) the wire standoff has an end portion; (ii) the wire standoff is secured to the washer by the end portion; and (iii) the end portion has a hook for securing the end portion to the washer, the hook of the end portion having a bend angle in the range of 70 to 180 degrees; wherein the outer tube houses the catalyst support components and the wire standoff. a) an outer tube, b) multiple catalyst support components arranged on a center support, the catalyst support components having an outer circumferential face, the catalyst support components being positioned in the outer tube; c) a wire standoff, a portion of the wire standoff being positioned between the outer tube and the catalyst support components to prevent the catalyst support components from contacting the outer tube, and d) a washer being positioned in the outer tube, wherein (i) the wire standoff has an end portion; (ii) the wire standoff is secured to the washer by the end portion; and (iii) the end portion has a hook for securing the end portion to the washer, the hook of the end portion having a bend angle in the range of 70 to 180 degrees; wherein the outer tube houses the catalyst support components and the wire standoff.
A hydraulic actuator having a housing, a chamber which is arranged or formed in the housing and in which a piston is movably mounted and divides the chamber into a flexion chamber and an extension chamber, wherein a channel (41, 42) for hydraulic fluid leads from each of the flexion chamber and the extension chamber into the housing in order to produce a fluidic connection between the flexion chamber and the extension chamber, wherein at least one valve (51, 52, 53, 54) is arranged in the fluidic connection, wherein the channels (41, 42) lead out of the housing to a valve block in which the at least one valve (51, 52, 53, 54) is arranged and fluidically coupled with the channels (41, 42), wherein the valve block is connected to the housing, wherein flow channels (63, 64, 65, 66, 67) are arranged in the valve block, the flow channels (63, 64, 65, 66, 67) forming a fluidic connection between the flexion chamber and the extension chamber together with the channels (41, 42), wherein all the flow channels (63, 64, 65, 66, 67) in the valve block are fluidically coupled with a bore, wherein a compensation volume is arranged in the valve block, the compensation volume being fluidically coupled with the bore via one of the flow channels, wherein a screw having connecting channels (83, 84, 85, 87) which connect the flow channels (63, 64, 65, 66, 67) to one another is inserted in the bore, characterized in that the screw fixes the valve block to the housing. wherein a channel (41, 42) for hydraulic fluid leads from each of the flexion chamber and the extension chamber into the housing in order to produce a fluidic connection between the flexion chamber and the extension chamber, wherein at least one valve (51, 52, 53, 54) is arranged in the fluidic connection, wherein the channels (41, 42) lead out of the housing to a valve block in which the at least one valve (51, 52, 53, 54) is arranged and fluidically coupled with the channels (41, 42), wherein the valve block is connected to the housing, wherein flow channels (63, 64, 65, 66, 67) are arranged in the valve block, the flow channels (63, 64, 65, 66, 67) forming a fluidic connection between the flexion chamber and the extension chamber together with the channels (41, 42), wherein all the flow channels (63, 64, 65, 66, 67) in the valve block are fluidically coupled with a bore, wherein a compensation volume is arranged in the valve block, the compensation volume being fluidically coupled with the bore via one of the flow channels, wherein a screw having connecting channels (83, 84, 85, 87) which connect the flow channels (63, 64, 65, 66, 67) to one another is inserted in the bore, characterized in that the screw fixes the valve block to the housing.
A radio communication terminal that performs machine communication via a base station apparatus of a radio communication system that is operated such that a frequency becomes a first band set depending on performance which a second radio communication terminal supports, the radio communication terminal comprising: a receiving section that has receiving performance to be able to support the first band, and that decodes an entire band of the first band at least with respect to a time domain where a downlink control channel is allocated; and a transmission section that has transmission performance limited to support a second band having a narrower bandwidth than the first band, and that allocates an uplink data channel including data sent by an uplink control channel in the second band. a receiving section that has receiving performance to be able to support the first band, and that decodes an entire band of the first band at least with respect to a time domain where a downlink control channel is allocated; and a transmission section that has transmission performance limited to support a second band having a narrower bandwidth than the first band, and that allocates an uplink data channel including data sent by an uplink control channel in the second band.
A method of preparing an isolated peptide comprising a lipophilically modified lysine side chain, comprising the steps of: (i) assembling the amino acid sequence of said peptide with protected reactive functional groups in the side chains in a step-wise manner using solid phase peptide synthesis (SPPS), wherein the side chain of lysine to be modified is protected by a trityl-based protecting group, particularly monomethoxytrityl (Mmt) or 4-methyltrityl (Mtt); (ii) drying the solid phase resin after the assembling of the amino acid sequence has been completed; (iii) treating the dried resin several times with a solution of 0.5 to 1.5% (v/v) trifluoroacetic acid in dichloromethane in order to deprotect the lysine side chain to be modified, wherein the number of TFA in DCM treatments is adjusted such that the yield of modified lysine side chain in step (ix) is at least 85% as compared to peptide without modified lysine side chain; (iv) neutralizing the resin; (v) coupling at least one activated 9-fluorenylmethyloxycarbonyl (Fmoc)-bound linker moiety to the deprotected lysine side chain; (vi) deprotecting the terminal functional group of the linker coupled to the lysine side chain in step (v); (vii) coupling an activated lipophilic moiety, particularly an activated fatty acid, to the deprotected terminal functional group of the linker of step (vi); (viii) drying the resin; and (ix) cleaving the peptide from the resin, wherein the isolated peptide is an exendin-4 derivative having a length of between 30 and 44, particularly between 38 and 40 amino acids, wherein the sequence identity to wild-type exendin-4 (SEQ ID NO.: 3) in the region corresponding to amino acids 1-13 of wild-type exendin is at least 65%. (i) assembling the amino acid sequence of said peptide with protected reactive functional groups in the side chains in a step-wise manner using solid phase peptide synthesis (SPPS), wherein the side chain of lysine to be modified is protected by a trityl-based protecting group, particularly monomethoxytrityl (Mmt) or 4-methyltrityl (Mtt); (ii) drying the solid phase resin after the assembling of the amino acid sequence has been completed; (iii) treating the dried resin several times with a solution of 0.5 to 1.5% (v/v) trifluoroacetic acid in dichloromethane in order to deprotect the lysine side chain to be modified, wherein the number of TFA in DCM treatments is adjusted such that the yield of modified lysine side chain in step (ix) is at least 85% as compared to peptide without modified lysine side chain; (iv) neutralizing the resin; (v) coupling at least one activated 9-fluorenylmethyloxycarbonyl (Fmoc)-bound linker moiety to the deprotected lysine side chain; (vi) deprotecting the terminal functional group of the linker coupled to the lysine side chain in step (v); (vii) coupling an activated lipophilic moiety, particularly an activated fatty acid, to the deprotected terminal functional group of the linker of step (vi); (viii) drying the resin; and (ix) cleaving the peptide from the resin,
A structure stamp with - a flexible stamp which has a microstructured or nanostructured stamp surface for embossing of an embossing structure which corresponds to the stamp surface on an embossing surface, - a frame for clamping the stamp, characterized in that the stamp is made flexible such that the stamp can expand with a line force by means of an embossing element beyond a surface plane E which is defined by the frame. - a flexible stamp which has a microstructured or nanostructured stamp surface for embossing of an embossing structure which corresponds to the stamp surface on an embossing surface, - a frame for clamping the stamp, characterized in that the stamp is made flexible
Elastomer comprising 1,3-diene monomer units and bearing pendant carbonate functions located outside the elastomer chain ends, the carbonate functions being present in monomer units of a vinyl monomer which is at least substituted with a group containing a 1,3-dioxolan-2-one ring.
A method of combusting fuel in a rotary engine, the method comprising: injecting a main quantity of the fuel, optionally heavy fuel, directly into a combustion chamber of the rotary engine to form a first fuel-air mixture within the combustion chamber, the first fuel-air mixture having a first air-fuel equivalence ratio A higher than 1; injecting a pilot quantity of the fuel into a pilot subchamber to form a second fuel-air mixture within the pilot subchamber, the second fuel-air mixture having a second air-fuel equivalence ratio A smaller than the first air-fuel equivalence ratio; igniting the second fuel-air mixture within the pilot subchamber; using the ignited second fuel-air mixture from the pilot subchamber to ignite the first fuel-air mixture; and after igniting the first fuel-air mixture, injecting a supplemental quantity of the fuel directly into the combustion chamber, the supplemental quantity being injected upstream of an exhaust port of the rotary engine with respect to a direction of rotation of a rotor. injecting a main quantity of the fuel, optionally heavy fuel, directly into a combustion chamber of the rotary engine to form a first fuel-air mixture within the combustion chamber, the first fuel-air mixture having a first air-fuel equivalence ratio A higher than 1; injecting a pilot quantity of the fuel into a pilot subchamber to form a second fuel-air mixture within the pilot subchamber, the second fuel-air mixture having a second air-fuel equivalence ratio A smaller than the first air-fuel equivalence ratio; igniting the second fuel-air mixture within the pilot subchamber; using the ignited second fuel-air mixture from the pilot subchamber to ignite the first fuel-air mixture; and after igniting the first fuel-air mixture, injecting a supplemental quantity of the fuel directly into the combustion chamber, the supplemental quantity being injected upstream of an exhaust port of the rotary engine with respect to a direction of rotation of a rotor.