mhurhangee/ep-ind-claims huggingface dataset:
A growing method for pluripotent stem cells, characterized by growing said pluripotent stem cells in a dispersed state while maintaining their undifferentiated state and pluripotency, using a liquid medium and a culturing vessel having immobilized or coated on a substrate solid phase surface a molecule belonging to the cadherin family, without using feeder cells.
An insulation barrier for use in an electrical energy storage system, the insulation barrier comprising: at least one insulation layer having a thermal conductivity through a thickness dimension of said insulation layer acquired according to ASTM C518 standard at a temperature of about 37.5 °C at atmospheric pressure in ambient environment, and under a compression load of about 2 psi of less than about 50 mW/m-K at 25 °C and less than about 60 mW/m-K at 600 °C; a support member surrounding at least a portion of a perimeter of the insulation layer, the support member having a flexural modulus greater than the flexural modulus of the insulation layer; an encapsulation layer at least partially surrounding the insulation layer, wherein the encapsulation layer is in the form of a film, an envelope or a bag and contacts at least a portion of the support member; and one or more adhesive pads coupled to the encapsulation layer. at least one insulation layer having a thermal conductivity through a thickness dimension of said insulation layer acquired according to ASTM C518 standard at a temperature of about 37.5 °C at atmospheric pressure in ambient environment, and under a compression load of about 2 psi of less than about 50 mW/m-K at 25 °C and less than about 60 mW/m-K at 600 °C; a support member surrounding at least a portion of a perimeter of the insulation layer, the support member having a flexural modulus greater than the flexural modulus of the insulation layer; an encapsulation layer at least partially surrounding the insulation layer, wherein the encapsulation layer is in the form of a film, an envelope or a bag and contacts at least a portion of the support member; and one or more adhesive pads coupled to the encapsulation layer.
A method for the preparation of a mirtazapine precursor of formula IIIb: wherein X represents -CO-Q; comprising the steps of: (a) reacting a compound of formula Ib with a compound of formula II to provide a compound of formula IIIb1: wherein Z 1 and Z 2 are leaving groups, and Q represents -OR or -NHMe where R is H or C 1-4 alkyl, or Q represents -NMe-C 2 H 4 -L where L is a leaving group; (b) subjecting the compound of formula IIIb1 to an optical resolution step; (c) separating the desired enantiomer; (d) racemising the undesired enantiomer; (e) recycling the racemised undesired enantiomer to the optical resolution of step (b). (a) reacting a compound of formula Ib with a compound of formula II to provide a compound of formula IIIb1: wherein Z 1 and Z 2 are leaving groups, and Q represents -OR or -NHMe where R is H or C 1-4 alkyl, or Q represents -NMe-C 2 H 4 -L where L is a leaving group; (b) subjecting the compound of formula IIIb1 to an optical resolution step; (c) separating the desired enantiomer; (d) racemising the undesired enantiomer; (e) recycling the racemised undesired enantiomer to the optical resolution of step (b).
A vehicle comprising: a sensor unit configured to sense infrared light emitted from one or more areas inside the vehicle; a blocking unit located between the sensor unit and the one or more areas inside the vehicle; and a controller configured to: control at least one of the blocking unit or the sensor unit in order to block or not to block infrared light so as to vary an amount of infrared light that the sensor unit is able to receive through the blocking unit from the one or more areas inside the vehicle; and determine, based on a variation in the amount of infrared light received by the sensor unit, whether or not a living body is present in the one or more of the areas inside the vehicle. a sensor unit configured to sense infrared light emitted from one or more areas inside the vehicle; a blocking unit located between the sensor unit and the one or more areas inside the vehicle; and a controller configured to: control at least one of the blocking unit or the sensor unit in order to block or not to block infrared light so as to vary an amount of infrared light that the sensor unit is able to receive through the blocking unit from the one or more areas inside the vehicle; and determine, based on a variation in the amount of infrared light received by the sensor unit, whether or not a living body is present in the one or more of the areas inside the vehicle. control at least one of the blocking unit or the sensor unit in order to block or not to block infrared light so as to vary an amount of infrared light that the sensor unit is able to receive through the blocking unit from the one or more areas inside the vehicle; and determine, based on a variation in the amount of infrared light received by the sensor unit, whether or not a living body is present in the one or more of the areas inside the vehicle.
Apparatus for modifying a parameterized representation having, for a time portion of an audio signal, band pass filter information for a plurality of band pass filters, the band pass filter information indicating time-varying band pass filter center frequencies of band pass filters having band widths, which depend on the time-varying band pass filter center frequencies of the corresponding band pass filters, and having amplitude modulation information or phase modulation information or frequency modulation information for each band pass filter for the time portion of the audio signal, the modulation information being related to the time-varying band pass filter center frequencies of the band pass filters, the apparatus comprising: a modifier for modifying the time-varying band pass filter center frequencies to obtain modified time-varying band pass filter center frequencies and for generating a modified parameterized representation comprising the modified time-varying band pass filter center frequencies. having, for a time portion of an audio signal, band pass filter information for a plurality of band pass filters, the band pass filter information indicating time-varying band pass filter center frequencies of band pass filters having band widths, which depend on the time-varying band pass filter center frequencies of the corresponding band pass filters, and having amplitude modulation information or phase modulation information or frequency modulation information for each band pass filter for the time portion of the audio signal, the modulation information being related to the time-varying band pass filter center frequencies of the band pass filters,
An automatically moving floor treatment appliance comprising an appliance housing, a drive means for the movement of the floor treatment appliance within a surrounding area, at least one fall sensor (8, 9, 10, 11, 12, 13, 14, 15) arranged on an underside of the appliance housing facing a surface, which is configured to detect a distance (a) of the floor treatment appliance from the surface, and a computing means, which is configured to compare the distance (a) detected by means of the fall sensor (8, 9, 10, 11, 12, 13, 14, 15) with a threshold value defining a slope and, in the event that the detected distance (a) is greater than the defined threshold value, to determine the presence of a slope as detection result, and to transmit a control command for changing a movement of the floor treatment appliance to the drive means, characterized in that, on the underside of the appliance housing, the floor treatment appliance has a plurality of fall sensors (8, 9, 10, 11, 12, 13, 14, 15), which are arranged one behind the other in the direction of a circumferential contour of the underside, wherein the computing means is configured to compare a detection result of a fall sensor (8, 9, 10, 11, 12, 13, 14, 15) with a known reference result, and, in the event that the detection result does not correspond with the reference result, to determine a malfunctioning of the fall sensor (8, 9, 10, 11, 12, 13, 14, 15), wherein the computing means is configured to compare distances (a) detected chronologically successively by the same fall sensor (8, 9, 10, 11, 12, 13, 14, 15) during a movement of the floor treatment appliance with one another, and, in the event that the distances (a) are identical, to determine a malfunctioning of the fall sensor (8, 9, 10, 11, 12, 13, 14, 15), and/or wherein the computing means is configured to compare a detection result of a fall sensor (8, 9, 10, 11, 12, 13, 14, 15) with a detection result of at least one further fall sensor (8, 9, 10, 11, 12, 13, 14, 15) trailing the fall sensor (8, 9, 10, 11, 12, 13, 14, 15) in the direction of movement, and, in the event that the trailing fall sensor (8, 9, 10, 11, 12, 13, 14, 15) detects a slope without the leading fall sensor (8, 9, 10, 11, 12, 13, 14, 15) having detected the slope before, to determine a malfunctioning of the fall sensor (8, 9, 10, 11, 12, 13, 14, 15), wherein the floor treatment appliance is initially further operated, under the condition that the trailing fall sensor (8, 9, 10, 11, 12, 13, 14, 15) now takes over the securing function of the defective leading fall sensor (8, 9, 10, 11, 12, 13, 14, 15).
An oral care implement (100, 200) comprising: a head (110, 210) having a front surface (112, 212); and a plurality of tooth cleaning elements (105, 205) comprising: a plurality of inclined bristle tufts (150, 250) circumferentially arranged about a first reference ring (R 1) on the front surface (112, 212) that surrounds a reference axis (R A) that intersects the front surface (112, 212), each of the plurality of inclined bristle tufts (150, 250) extending from the front surface (112, 212) of the head (110, 210) so as to converge toward the reference axis (R A) with increasing distance from the front surface (112, 212); and characterized in that an elastomeric member (170, 270) extending from the front surface (112, 212) of the head (110, 210) at a position within the first reference ring (R 1); wherein the elastomeric member (170, 270) has a truncated conical shape terminating in a flattened top surface. a head (110, 210) having a front surface (112, 212); and a plurality of tooth cleaning elements (105, 205) comprising: a plurality of inclined bristle tufts (150, 250) circumferentially arranged about a first reference ring (R 1) on the front surface (112, 212) that surrounds a reference axis (R A) that intersects the front surface (112, 212), each of the plurality of inclined bristle tufts (150, 250) extending from the front surface (112, 212) of the head (110, 210) so as to converge toward the reference axis (R A) with increasing distance from the front surface (112, 212); and characterized in that a plurality of inclined bristle tufts (150, 250) circumferentially arranged about a first reference ring (R 1) on the front surface (112, 212) that surrounds a reference axis (R A) that intersects the front surface (112, 212), each of the plurality of inclined bristle tufts (150, 250) extending from the front surface (112, 212) of the head (110, 210) so as to converge toward the reference axis (R A) with increasing distance from the front surface (112, 212); and characterized in that an elastomeric member (170, 270) extending from the front surface (112, 212) of the head (110, 210) at a position within the first reference ring (R 1); wherein the elastomeric member (170, 270) has a truncated conical shape terminating in a flattened top surface.
An image processing apparatus comprising at least one processor, wherein the processor is configured to: derive, at each pixel of a plurality of tubular structures, running vectors being unit vectors representing directions running from the pixel in which a tubular structure is present based on a medical image including the plurality of tubular structures; and separate the plurality of tubular structures along the running vectors; characterised in that the processor is configured to, based on an angle formed by a direction vector from a first pixel to a second pixel and the running vector at at least one of the first pixel or the second pixel, determine the likelihood that the same label is assigned to the first pixel and the second pixel to separate the plurality of tubular structures, wherein the smaller the angle the higher the likelihood that the same label is assigned to the first and second pixels. derive, at each pixel of a plurality of tubular structures, running vectors being unit vectors representing directions running from the pixel in which a tubular structure is present based on a medical image including the plurality of tubular structures; and separate the plurality of tubular structures along the running vectors; characterised in that the processor is configured to, based on an angle formed by a direction vector from a first pixel to a second pixel and the running vector at at least one of the first pixel or the second pixel, determine the likelihood that the same label is assigned to the first pixel and the second pixel to separate the plurality of tubular structures, wherein the smaller the angle the higher the likelihood that the same label is assigned to the first and second pixels.
Method for inspecting the butt weld of two transverse ends of two metal strips (1a, 1b), said ends respectively being moved closer and held between first and second jaws (2a, 2b) thus placed along each of the transverse ends, wherein - the first and second jaws have at least a spacing such that a gap (54, 55) is formed in order to let pass a first channel of transmission of incident waves able to generate ultrasonic waves on a surface of the first strip and to let pass a second channel of transmission of waves emerging from the surface of the second strip; - the incident waves of the first channel are generated by means of laser pulses in a regime at least provided to achieve a third channel of ultrasonic waves generated on the surface of the first strip, passing through the weld and emerging into the second channel; the third wave channel being embodied by a "strip-weld-strip" junction (54, 1c, 55) on and in which the waves propagate; and - on the basis of a step of analysing the regime associated with the pulses and of at least one measurement of a signature of a vibratory state of the surface of the second strip at the point where the ultrasonic waves emerge into the second channel, inspection characteristics of the weld are extracted for identification, the signature of a weld under inspection being compared to standard measurement signatures of welding defects indexed in a databank. - the first and second jaws have at least a spacing such that a gap (54, 55) is formed in order to let pass a first channel of transmission of incident waves able to generate ultrasonic waves on a surface of the first strip and to let pass a second channel of transmission of waves emerging from the surface of the second strip; - the incident waves of the first channel are generated by means of laser pulses in a regime at least provided to achieve a third channel of ultrasonic waves generated on the surface of the first strip, passing through the weld and emerging into the second channel; the third wave channel being embodied by a "strip-weld-strip" junction (54, 1c, 55) on and in which the waves propagate; and - on the basis of a step of analysing the regime associated with the pulses and of at least one measurement of a signature of a vibratory state of the surface of the second strip at the point where the ultrasonic waves emerge into the second channel, inspection characteristics of the weld are extracted for identification, the signature of a weld under inspection being compared to standard measurement signatures of welding defects indexed in a databank.
An ion mobility spectrometry method comprising: (i) applying a voltage difference between a first electrode of an ion gate and a second electrode of the ion gate to prevent ions from leaving a reaction region of an ion mobility spectrometer; (ii) opening the ion gate to allow the ions to travel from the reaction region into a modification region between the first electrode and the second electrode; (iii) applying a radio frequency, RF, voltage between the first electrode and the second electrode to fragment the ions in the modification region to provide daughter ions; (iv) allowing the daughter ions to travel from the modification region into a drift region of the ion mobility spectrometer towards a collector; (v) closing the ion gate; and (vi) determining the time of flight of the daughter ions from the ion gate to the collector. (i) applying a voltage difference between a first electrode of an ion gate and a second electrode of the ion gate to prevent ions from leaving a reaction region of an ion mobility spectrometer; (ii) opening the ion gate to allow the ions to travel from the reaction region into a modification region between the first electrode and the second electrode; (iii) applying a radio frequency, RF, voltage between the first electrode and the second electrode to fragment the ions in the modification region to provide daughter ions; (iv) allowing the daughter ions to travel from the modification region into a drift region of the ion mobility spectrometer towards a collector; (v) closing the ion gate; and (vi) determining the time of flight of the daughter ions from the ion gate to the collector.
A floral gift box (30, 42, 52), comprising: a base box (32, 44, 54) having a first cut-out region (38, 46, 56) in a top thereof; floral foam within said base box and beneath said first cut-out region; a cover receiving said base box; and said first cut-out region receiving a floral arrangement (48, 58) having cut stems received by said block of floral foam; characterized by: said floral foam comprising a block of floral foam maintained in a sealed tray; said base box comprising a box slidably receiving a sleeve thereover, said sleeve having said first cut-out region (38, 46, 56); and said cover being transparent and interlocking said box and sleeve. a base box (32, 44, 54) having a first cut-out region (38, 46, 56) in a top thereof; floral foam within said base box and beneath said first cut-out region; a cover receiving said base box; and said first cut-out region receiving a floral arrangement (48, 58) having cut stems received by said block of floral foam; characterized by: said floral foam comprising a block of floral foam maintained in a sealed tray; said base box comprising a box slidably receiving a sleeve thereover, said sleeve having said first cut-out region (38, 46, 56); and said cover being transparent and interlocking said box and sleeve. said floral foam comprising a block of floral foam maintained in a sealed tray; said base box comprising a box slidably receiving a sleeve thereover, said sleeve having said first cut-out region (38, 46, 56); and said cover being transparent and interlocking said box and sleeve.
A vehicle function broadcasting method, characterized by comprising: Step S 1: determining whether input information is a vehicle function broadcasting instruction, and if so, implementing Step S2; Step S2: acquiring a historical record of use of vehicle functions, and arranging the vehicle functions in a reverse order according to the frequency of use of the vehicle functions and generating a broadcasting list; and Step S3: broadcasting the vehicle functions according to the broadcasting list. Step S 1: determining whether input information is a vehicle function broadcasting instruction, and if so, implementing Step S2; Step S2: acquiring a historical record of use of vehicle functions, and arranging the vehicle functions in a reverse order according to the frequency of use of the vehicle functions and generating a broadcasting list; and Step S3: broadcasting the vehicle functions according to the broadcasting list.
A surgical apparatus for positioning within a tissue tract accessing an underlying body cavity, which comprises: a seal anchor member defining a longitudinal axis and a length, the seal anchor member including a first end and a second end, the first end configured to fold along the longitudinal axis, the first end defining a plurality of states including a plurality of folded states, each state corresponding to a different length of the seal anchor member; characterized in that the first end defines a slot configured to facilitate transition within the plurality of folded states, wherein the first end further defines an aperture, and a pin disposed through the aperture and the slot to facilitate transition within the plurality of folded states. a seal anchor member defining a longitudinal axis and a length, the seal anchor member including a first end and a second end, the first end configured to fold along the longitudinal axis, the first end defining a plurality of states including a plurality of folded states, each state corresponding to a different length of the seal anchor member; characterized in that the first end defines a slot configured to facilitate transition within the plurality of folded states, wherein the first end further defines an aperture, and a pin disposed through the aperture and the slot to facilitate transition within the plurality of folded states.
A method performed by an integrated access and backhaul, IAB, node, the method comprising: in response to expiry of a radio link failure, RLF, timer, determining a failure in a backhaul link between the IAB node and an uplink IAB node; in response to determining the failure in the backhaul link, determining whether there is another IAB node available for backhaul link reestablishment; and in response to determining that there is not another IAB node available for backhaul link reestablishment, transmitting, to a downlink IAB node, a signaling message indicating the failure in the backhaul link. in response to expiry of a radio link failure, RLF, timer, determining a failure in a backhaul link between the IAB node and an uplink IAB node; in response to determining the failure in the backhaul link, determining whether there is another IAB node available for backhaul link reestablishment; and in response to determining that there is not another IAB node available for backhaul link reestablishment, transmitting, to a downlink IAB node, a signaling message indicating the failure in the backhaul link.
A compound, or a pharmaceutically acceptable salt thereof, having the structure of formula: wherein: R 1 is -OH, -OR 4, -NHOR 5, -NHSO 2 R 4, -NR 4 R 5 or R 4; or -C(=O)R 1 is a carboxylic acid bioisostere having the structure Ring A is monocyclic 5- or 6-membered heteroaryl; L 2 is absent, -O-(CH 2)-, or -S-(CH 2)-; R 2 is hydrogen, halogen, nitro, -CN, -OH, -OR 4, C 1 -C 6 alkyl, C 1 -C 6 fluoroalkyl, or C 3 -C 6 cycloalkyl; n is 0, 1, 2, 3, or 4; R 3 is C 1 -C 6 alkyl, C 1 -C 6 fluoroalkyl, C 3 -C 6 cycloalkyl, or aryl; X is -OH, -OR 4, halogen, C 1 -C 6 alkyl, C 1 -C 6 fluoroalkyl, or C 3 -C 6 cycloalkyl; Z is -OH, -OR 4, halogen, C 1 -C 6 alkyl, C 1 -C 6 fluoroalkyl, or C 3 -C 6 cycloalkyl; R 4 is C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, aryl, or heteroaryl; R 5 is hydrogen, C 1 -C 6 alkyl, C 1 -C 6 fluoroalkyl, C 3 -C 6 cycloalkyl, or aryl; or R 4 and R 5 taken together with the nitrogen to which they are attached to form a C 2 -C 8 heterocycloalkyl. R 1 is -OH, -OR 4, -NHOR 5, -NHSO 2 R 4, -NR 4 R 5 or R 4; or -C(=O)R 1 is a carboxylic acid bioisostere having the structure Ring A is monocyclic 5- or 6-membered heteroaryl; L 2 is absent, -O-(CH 2)-, or -S-(CH 2)-; R 2 is hydrogen, halogen, nitro, -CN, -OH, -OR 4, C 1 -C 6 alkyl, C 1 -C 6 fluoroalkyl, or C 3 -C 6 cycloalkyl; n is 0, 1, 2, 3, or 4; R 3 is C 1 -C 6 alkyl, C 1 -C 6 fluoroalkyl, C 3 -C 6 cycloalkyl, or aryl; X is -OH, -OR 4, halogen, C 1 -C 6 alkyl, C 1 -C 6 fluoroalkyl, or C 3 -C 6 cycloalkyl; Z is -OH, -OR 4, halogen, C 1 -C 6 alkyl, C 1 -C 6 fluoroalkyl, or C 3 -C 6 cycloalkyl; R 4 is C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, aryl, or heteroaryl; R 5 is hydrogen, C 1 -C 6 alkyl, C 1 -C 6 fluoroalkyl, C 3 -C 6 cycloalkyl, or aryl; or R 4 and R 5 taken together with the nitrogen to which they are attached to form a C 2 -C 8 heterocycloalkyl.