mhurhangee/ep-ind-claims huggingface dataset:
Lipid layer forming on skin or a mucous membrane, carrier composition for topical administration, comprising volatile silicone oil, from 10 % by weight to 30 % by weight of phospholipid, from 10 % by weight to 30 % by weight of ethanol, optionally water in an amount of 5 % by weight or less, wherein the silicone oil has a boiling point above 180°C, in particular above 200°C, and wherein the silicone oil has a heat of vaporization (kJ/kg) at 25 °C of from about 100 kJ/kg to about 300 kJ/kg, with the proviso that the content of volatile silicone oil is 50 % by weight or more.
A copolymer comprising: from 35 wt% to 80 wt% units derived from ethylene; and at least 1.0 wt% of units derived from propylene, based on the weight of the copolymer, wherein the copolymer has: a melting peak (Tm), as measured by DSC, of 80° C or less; a polydispersity index of 2.8 or less; has an intramolecular composition distribution of 15 wt% or less; and a weight-average molecular weight (Mw) of from 80,000 to 400,000. from 35 wt% to 80 wt% units derived from ethylene; and at least 1.0 wt% of units derived from propylene, based on the weight of the copolymer, a melting peak (Tm), as measured by DSC, of 80° C or less; a polydispersity index of 2.8 or less; has an intramolecular composition distribution of 15 wt% or less; and a weight-average molecular weight (Mw) of from 80,000 to 400,000.
A PF-4 interacting heparinoid for use in a method of attenuating a myelosuppressive side effect of a myelosuppressive treatment regimen, said method comprising: adjunctively administering said PF-4 interacting heparinoid to a patient receiving a myelosuppressive treatment regimen, wherein the PF-4 heparinoid is substantially desulfated at the 2-O position and 3-O position, and wherein the patient is a human.
Use of an austenitic steel having the following composition: 0.01 to 0.12 percent by mass of carbon, 0.05 to 0.5 percent by mass of silicon, 9 to 13 percent by mass of manganese, 16 to 20 percent by mass of chromium, 6 to 9 percent by mass of nickel, 0.01 to 0.5 percent by mass of aluminum, 1 to 4 percent by mass of copper, ≤ 0.04 percent by mass of boron, the remainder being iron and melting-related steel companion elements for hydrogen technology in motor vehicles in the temperature range from -253 °C to +100 °C and pressure range from 0.1 to 100 MPa. 0.01 to 0.12 percent by mass of carbon, 0.05 to 0.5 percent by mass of silicon, 9 to 13 percent by mass of manganese, 16 to 20 percent by mass of chromium, 6 to 9 percent by mass of nickel, 0.01 to 0.5 percent by mass of aluminum, 1 to 4 percent by mass of copper, ≤ 0.04 percent by mass of boron, the remainder being iron and melting-related steel companion elements for hydrogen technology in motor vehicles in the temperature range from -253 °C to +100 °C and pressure range from 0.1 to 100 MPa.
A method of controlling an electric power assisted steering system comprising one or more inverter bridges each connected to a multi-phase motor configured to provide power assist to steering of a vehicle, wherein each inverter comprises a plurality of switching elements (122A, 122B, 124A, 124B, 126A, 126B) each associated with a phase of the motor, the method comprising: in response to detecting a predefined event affecting current flow in one or more of the inverter bridges, preventing current flow in said one or more affected inverters by applying a gate-source voltage to one or more of the switching elements (122A, 122B, 124A, 124B, 126A, 126B) of the affected inverter bridge(s), wherein the switching elements are configured to conduct in the off-state when reverse biased beyond a reverse conduction threshold voltage, characterised in that applying the gate-source voltage comprises applying a negative gate-source voltage to control the reverse conduction threshold voltage of the switching elements in the off-state only at a time when there is no current flowing in the direction drain to source through the switching device that exceeds a threshold value.
A method for reporting user equipment UE capability information, wherein the method comprises: generating one data packet of UE capability information in a Radio Resource Control, RRC, layer; when determining a size of the data packet of the UE capability information exceeds a maximum Packet Data Convergence Protocol service data unit, PDCP SDU, size, splitting the data packet of the UE capability information into at least two split data packets in the RRC layer, wherein each split data packet of the at least two split data packets does not exceed the maximum PDCP SDU size; and reporting the at least two split data packets to a network side device via at least two RRC messages, wherein each RRC message carries one split data packet, and each RRC message comprises first indication information, the first indication information indicates an order of currently reported split data packet in the at least two split data packets. generating one data packet of UE capability information in a Radio Resource Control, RRC, layer; when determining a size of the data packet of the UE capability information exceeds a maximum Packet Data Convergence Protocol service data unit, PDCP SDU, size, splitting the data packet of the UE capability information into at least two split data packets in the RRC layer, wherein each split data packet of the at least two split data packets does not exceed the maximum PDCP SDU size; and reporting the at least two split data packets to a network side device via at least two RRC messages, wherein each RRC message carries one split data packet, and each RRC message comprises first indication information, the first indication information indicates an order of currently reported split data packet in the at least two split data packets.
A process for the preparation of a compound of formula I, or a salt or solvate thereof, wherein R 1 represents a nitrogen protecting group that is carboxybenzyl (Cbz); which process comprises reaction of a compound of formula II, or a salt or solvate thereof, wherein X 1 represents a suitable leaving group, with a compound of formula III, or a salt, solvate or a protected derivative thereof, wherein R 1 is as defined above. or a salt or solvate thereof, wherein R 1 represents a nitrogen protecting group that is carboxybenzyl (Cbz); which process comprises reaction of a compound of formula II, or a salt or solvate thereof, wherein X 1 represents a suitable leaving group, with a compound of formula III, or a salt, solvate or a protected derivative thereof, wherein R 1 is as defined above.
A roofing system, comprising several roofing elements, - wherein the roofing system comprises an end element and a middle element as roofing elements, - wherein all roofing elements comprise a frame and a shield, - wherein the roofing elements are designed as arched roofing elements by longitudinal frame sections arranged on respectively opposite longitudinal edges of the shield, - wherein the arched roofing elements can in each case be placed on a substrate with two opposite transverse edges, - wherein one of the longitudinal frame sections of the end element is formed by an arc segment, - wherein this arc segment is limited in side view to its outer side surface by an arc and a chord running in a plane with the transverse edges, - wherein this arc segment is formed stably such that the end element with the outer side surface of its arc segment can be set down on the substrate and - wherein this arc segment is designed stably in such a manner that the other roofing elements are movable into the end element in such a manner that these are in each case in contact with one of their longitudinal frame sections with an inner side surface of the arc segment of the end element, characterized in - that the end element is also used in a position tilted by 90°, in which this rests with the outer side surface of its arc segment on the substrate, as a mounting device for the further roofing elements, in which the further roofing elements in each case tilted by 90° can be set down on the arc segment, so that a compact packet results from the roofing elements. - wherein the roofing system comprises an end element and a middle element as roofing elements, - wherein all roofing elements comprise a frame and a shield, - wherein the roofing elements are designed as arched roofing elements by longitudinal frame sections arranged on respectively opposite longitudinal edges of the shield, - wherein the arched roofing elements can in each case be placed on a substrate with two opposite transverse edges, - wherein one of the longitudinal frame sections of the end element is formed by an arc segment, - wherein this arc segment is limited in side view to its outer side surface by an arc and a chord running in a plane with the transverse edges, - wherein this arc segment is formed stably such that the end element with the outer side surface of its arc segment can be set down on the substrate and - wherein this arc segment is designed stably in such a manner that the other roofing elements are movable into the end element in such a manner that these are in each case in contact with one of their longitudinal frame sections with an inner side surface of the arc segment of the end element, - that the end element is also used in a position tilted by 90°, in which this rests with the outer side surface of its arc segment on the substrate, as a mounting device for the further roofing elements, in which the further roofing elements in each case tilted by 90° can be set down on the arc segment, so that a compact packet results from the roofing elements.
A treatment regimen comprising alvocidib for use in a method for the treatment of a hematologic cancer in a patient in need thereof, the method comprising administering the treatment regimen comprising alvocidib to the patient if a cancer cell specimen obtained from the bone marrow of the patient is MCL1 primed, wherein a cell is MCL1 primed if it shows a change in mitochondrial membrane potential of at least 15% upon contacting the cell with a BH3 mimetic that is selective for MCL-1.
A device for measuring a temperature of a conductor, comprising: a housing; a coil disposed at a bottom of the housing; a circuit board disposed inside the housing and spaced apart from the coil in a vertical direction relative to a placement plane of the device, the circuit board being powered by the coil; and a temperature sensor coupled to the circuit board, wherein the temperature sensor comprises a body and an elastic element disposed around the body, and the elastic element is adapted to be compressed to cause a bottom of the temperature sensor to contact the conductor in a state that the device is fixed to the conductor, characterized in that at least one sidewall of the housing is provided with an opening located at least in part between the circuit board and the coil in the vertical direction, so that air can flow between the exterior and interior of the housing through the opening. a housing; a coil disposed at a bottom of the housing; a circuit board disposed inside the housing and spaced apart from the coil in a vertical direction relative to a placement plane of the device, the circuit board being powered by the coil; and a temperature sensor coupled to the circuit board, wherein the temperature sensor comprises a body and an elastic element disposed around the body, and the elastic element is adapted to be compressed to cause a bottom of the temperature sensor to contact the conductor in a state that the device is fixed to the conductor,
A construct, or a pharmaceutically acceptable salt thereof, for use in the inhibition of metastasis of a cancer, said construct comprising: (a) a polyethylene glycol-block-poly(L-lysine) polymer moiety, wherein the polyethylene glycol is thiol-functionalized; (b) a cholecystokinin-B (CCK-B) receptor ligand coupled to the polyethylene glycol of the polymer moiety; and (c) a siRNA complexed with the poly(L-lysine) of the polymer moiety, wherein the construct is neutralized; and the siRNA is a GASTRIN-targeted siRNA. (a) a polyethylene glycol-block-poly(L-lysine) polymer moiety, wherein the polyethylene glycol is thiol-functionalized; (b) a cholecystokinin-B (CCK-B) receptor ligand coupled to the polyethylene glycol of the polymer moiety; and (c) a siRNA complexed with the poly(L-lysine) of the polymer moiety, wherein the construct is neutralized; and the siRNA is a GASTRIN-targeted siRNA.
A quick-clamping nut for location on a threaded element with an external thread, wherein the quick-clamping nut comprises at least two threaded parts (118, 120), which in an engagement position are in engagement with the external thread of the threaded element when the quick-clamping nut is arranged on the threaded element, and in a positioning position are out of engagement with the external thread of the threaded element and are displaceable in a longitudinal direction of the threaded element, wherein the threaded parts (118, 120) are transferable by a tipping movement relative to each other from the engagement position into the positioning position and from the positioning position into the engagement position. wherein the quick-clamping nut comprises a pressure plate, characterised in that the threaded parts (118, 120) have bearing sections with convex bearing faces with which the bearing sections extend into a seating of the pressure plate and which co-operate with a bearing face of the pressure plate such that the threaded parts (118, 120) are held on the pressure plate to be tiltable relative to a longitudinal axis of the pressure plate and the threaded parts (118, 120) and the pressure plate are held together in a captive manner.
A process for producing thermoelectric semiconductor materials by co-melting mixtures of the particular element constituents of the thermoelectric semiconductor materials or alloys thereof in an induction furnace and pouring the melt thus obtained into the mold of a thermoelectric leg, or spraying the melt thus obtained to produce a pulverulent thermoelectric semiconductor material, wherein element constituents of the thermoelectric semiconductor materials or low-reactivity alloys thereof are first co-melted, and then element constituents of the thermoelectric materials or higher-reactivity alloys thereof are added to this melt.
An absorbent article having a vertical direction and a lateral direction, the absorbent article comprising: an absorbent main body including an absorbent body, the absorbent main body having a longitudinal direction that conforms to the vertical direction; and waist-circumference sections (20, 30) in a pair respectively located on one end side and another end side in the longitudinal direction of the absorbent main body, the waist-circumference sections including an elastic member (22, 32) stretchable in the lateral direction, the absorbent main body including extension sections in a pair respectively extending outward on two lateral sides of the absorbent body, the extension sections each having an elastic member stretchable in the vertical direction placed therein, the extension sections being formed extending laterally outward from a position on a non-skin side of the absorbent body using a continuous sheet that is continuous in the lateral direction, a lateral welded region having a predetermined length in the lateral direction being placed in a portion where each of the extension sections forms a leg opening, vertical welded regions extending along the vertical direction being respectively placed in the extension sections at positions laterally inside of the lateral welded region. an absorbent main body including an absorbent body, the absorbent main body having a longitudinal direction that conforms to the vertical direction; and waist-circumference sections (20, 30) in a pair respectively located on one end side and another end side in the longitudinal direction of the absorbent main body, the waist-circumference sections including an elastic member (22, 32) stretchable in the lateral direction, the absorbent main body including extension sections in a pair respectively extending outward on two lateral sides of the absorbent body, the extension sections each having an elastic member stretchable in the vertical direction placed therein, the extension sections being formed extending laterally outward from a position on a non-skin side of the absorbent body using a continuous sheet that is continuous in the lateral direction, a lateral welded region having a predetermined length in the lateral direction being placed in a portion where each of the extension sections forms a leg opening, vertical welded regions extending along the vertical direction being respectively placed in the extension sections at positions laterally inside of the lateral welded region.
A composition comprising dextranase for use in a method for inhibiting colonization of an animal by Campylobacter, said method comprising the steps of administering orally to said animal said composition comprising the dextranase.
A compound selected in the group consisting of Nitazoxanide, Tizoxanide and Tizoxanide glucuronide, and a pharmaceutically acceptable salt of NTZ, TZ or TZG, for use in a method for the treatment of a fibrotic disorder in a mammal.
An audio processing circuit comprises: a time-to-frequency domain circuit (220, 260) configured to convert a primary audio signal and a secondary audio signal in a time-domain form and output frequency spectrum representations thereof; a cross-fade magnitude circuit configured to obtain a cross-faded magnitude spectrum representation from at least one of the frequency spectrum representations; a cross-fade phase circuit (270, 280) configured to obtain a separate cross-faded phase spectrum representation from at least one of the frequency spectrum representations; wherein the audio processing circuit is characterised in that the cross-fade phase circuit comprises a mixing circuit configured to mix the frequency spectrum representations (222, 262) of the primary audio signal and of the secondary audio signal with a time-varying complex spectrum mixing factor to produce a cross-faded signal, and to derive the phase spectrum representation of an output of the cross-faded signal to produce a cross-faded phase spectrum representation; and the audio processing circuit comprises a frequency-to-time domain circuit configured to receive and combine the separate cross-faded magnitude and cross-faded phase spectrum representations and output a time domain signal. a time-to-frequency domain circuit (220, 260) configured to convert a primary audio signal and a secondary audio signal in a time-domain form and output frequency spectrum representations thereof; a cross-fade magnitude circuit configured to obtain a cross-faded magnitude spectrum representation from at least one of the frequency spectrum representations; a cross-fade phase circuit (270, 280) configured to obtain a separate cross-faded phase spectrum representation from at least one of the frequency spectrum representations; wherein the audio processing circuit is characterised in that the cross-fade phase circuit comprises a mixing circuit configured to mix the frequency spectrum representations (222, 262) of the primary audio signal and of the secondary audio signal with a time-varying complex spectrum mixing factor to produce a cross-faded signal, and to derive the phase spectrum representation of an output of the cross-faded signal to produce a cross-faded phase spectrum representation; and the audio processing circuit comprises a frequency-to-time domain circuit configured to receive and combine the separate cross-faded magnitude and cross-faded phase spectrum representations and output a time domain signal.
An applicator for a fluid product such as a cosmetic product, of the type comprising a reservoir containing the product and an application head, coupled to the reservoir, comprising: - a tip for dispensing the product in communication with the reservoir including a face for dispensing the product on a surface to be treated such as the skin of a user, this tip defining a path for dispensing said product in communication with the reservoir, the path for dispensing the product extending through the dispensing tip and terminating in an orifice on the dispensing face, adapted to dispense the product on the surface to be treated, - a tip for thermal storage including a face for application on the surface to be treated. the tip for thermal storage is formed of a material whose thermal effusivity is higher than that of the tip for dispensing the product so as to provide two different thermal sensations in contact with the surface to be treated and, the applicator being characterized in that: - the application head is shaped so that, by selectively orienting the applicator relative to the surface to be treated, a user can place the latter in contact with the dispensing face of the dispensing tip while excluding any contact with the application face of the thermal storage tip, the respective dispensing and application faces of the dispensing tip and the thermal storage tip being defined by respective envelope surfaces not included into each other and disjointed. - a tip for dispensing the product in communication with the reservoir including a face for dispensing the product on a surface to be treated such as the skin of a user, this tip defining a path for dispensing said product in communication with the reservoir, the path for dispensing the product extending through the dispensing tip and terminating in an orifice on the dispensing face, adapted to dispense the product on the surface to be treated, - a tip for thermal storage including a face for application on the surface to be treated. - the application head is shaped so that, by selectively orienting the applicator relative to the surface to be treated, a user can place the latter in contact with the dispensing face of the dispensing tip while excluding any contact with the application face of the thermal storage tip, the respective dispensing and application faces of the dispensing tip and the thermal storage tip being defined by respective envelope surfaces not included into each other and disjointed.
An adhesive for an endoscope, comprising the following (a) to (c): (a) an epoxy resin including at least one of a bisphenol A epoxy resin, a bisphenol F epoxy resin, or a phenol novolac epoxy resin; (b) a polyamine compound having an oxygen atom but no amide bond in a molecule thereof; and (c) a metal alkoxide compound, wherein the polyamine compound has an oxyalkylene structure. (a) an epoxy resin including at least one of a bisphenol A epoxy resin, a bisphenol F epoxy resin, or a phenol novolac epoxy resin; (b) a polyamine compound having an oxygen atom but no amide bond in a molecule thereof; and (c) a metal alkoxide compound, wherein the polyamine compound has an oxyalkylene structure.
A monoclonal antibody to KIR2DS1 or a fragment comprising an antigen-binding region thereof, which specifically binds to KIR2DS1 and does not cross-react with KIR2DL1, 2 and 3 and KIR2DS2, that includes: VL comprising an amino acid sequence of SEQ ID NO: 1 as CDR1, comprising an amino acid sequence of SEQ ID NO: 2 as CDR2, and comprising an amino acid sequence of SEQ ID NO: 3 as CDR3; and VH comprising an amino acid sequence of SEQ ID NO: 4 or SEQ ID NO: 5 as CDR1, comprising an amino acid sequence of SEQ ID NO: 6 as CDR2, and comprising an amino acid sequence of any one selected from the group consisting of SEQ ID NO: 7, SEQ ID NO: 8, and SEQ ID NO: 9 as CDR3. VL comprising an amino acid sequence of SEQ ID NO: 1 as CDR1, comprising an amino acid sequence of SEQ ID NO: 2 as CDR2, and comprising an amino acid sequence of SEQ ID NO: 3 as CDR3; and VH comprising an amino acid sequence of SEQ ID NO: 4 or SEQ ID NO: 5 as CDR1, comprising an amino acid sequence of SEQ ID NO: 6 as CDR2, and comprising an amino acid sequence of any one selected from the group consisting of SEQ ID NO: 7, SEQ ID NO: 8, and SEQ ID NO: 9 as CDR3.