An ultrasound ablation neuromodulation catheter, comprising a catheter body, an ultrasound treatment transducer assembly, an ultrasound imaging transducer assembly, a control handle, and a transducer interface, wherein the catheter body is of a cylindrical structure; the ultrasound treatment transducer assembly is arranged on a lateral surface of a far end of the catheter body, the ultrasound treatment transducer assembly comprises at least two ultrasound treatment transducers, and a distance between two adjacent ultrasound treatment transducers is greater than or equal to 1cm; the ultrasound imaging transducer assembly comprises at least one ultrasound imaging transducer, and the ultrasound imaging transducer is arranged between two adjacent ultrasound treatment transducers; the control handle is arranged at a near end of the catheter body; and the transducer interface comprises a first interface connected to the ultrasound treatment transducer assembly and a second interface connected to the ultrasound imaging transducer, wherein each of the ultrasound treatment transducers is an unclosed circumferential wafer and a circumference angle of the unclosed circumferential wafer is greater than 0 degree and less than 360 degrees, wherein gaps without transmitting acoustic beams of at least two unclosed circumferential transducers are configured to be in parallel with or staggered with each other, wherein an axis of each of the unclosed circumferential wafers coincides with the axis of the catheter body, characterized in that the ultrasound ablation neuromodulation catheter further comprises at least one independent ultrasound imaging transducer, which is of a strip shape and is located at the gap of the unclosed circumferential wafer. the catheter body is of a cylindrical structure; the ultrasound treatment transducer assembly is arranged on a lateral surface of a far end of the catheter body, the ultrasound treatment transducer assembly comprises at least two ultrasound treatment transducers, and a distance between two adjacent ultrasound treatment transducers is greater than or equal to 1cm; the ultrasound imaging transducer assembly comprises at least one ultrasound imaging transducer, and the ultrasound imaging transducer is arranged between two adjacent ultrasound treatment transducers; the control handle is arranged at a near end of the catheter body; and the transducer interface comprises a first interface connected to the ultrasound treatment transducer assembly and a second interface connected to the ultrasound imaging transducer, wherein each of the ultrasound treatment transducers is an unclosed circumferential wafer and a circumference angle of the unclosed circumferential wafer is greater than 0 degree and less than 360 degrees, wherein gaps without transmitting acoustic beams of at least two unclosed circumferential transducers are configured to be in parallel with or staggered with each other, wherein an axis of each of the unclosed circumferential wafers coincides with the axis of the catheter body, characterized in that the ultrasound ablation neuromodulation catheter further comprises at least one independent ultrasound imaging transducer, which is of a strip shape and is located at the gap of the unclosed circumferential wafer.