mhurhangee/ep-ind-claims huggingface dataset:
A method of decreasing immunogenicity of an RNA encoding at least one peptide or protein, said method comprising modifying the nucleotide sequence of the RNA by reducing the uridine content, wherein said reduction of the U content comprises a substitution of U nucleosides by nucleosides other than U in the nucleotide sequence of the RNA, wherein said nucleosides other than U are selected from the group consisting of adenosine, guanosine, and cytidine, wherein the modified RNA is A-rich and the A content is increased by at least 20% compared to the non-modified RNA and wherein the amino acid sequence of the peptide or protein encoded by the modified RNA is identical to the amino acid sequence of the peptide or protein encoded by the non-modified RNA.
A fixing and sealing system for a solar roof comprising glass substrates, the fixing and sealing system comprising: - a plurality of longitudinal profiles designed to be positioned in parallel with one another, each longitudinal profile comprising a central groove and two lateral grooves (51, 52), - corner fixing parts designed to cooperate with the central groove of the longitudinal profiles, each corner fixing part being designed to hold the corners of two adjacent lateral glass substrates on the same longitudinal profile and to fix said adjacent lateral glass substrates simultaneously, characterised in that the fixing and sealing system further comprises transverse bars perpendicular to the plurality of longitudinal profiles, each transverse bar being fixed to two adjacent longitudinal profiles and each transverse bar comprising a stepped surface with a lower bearing and an upper bearing, the lower bearing being designed to support a lower glass substrate and the upper bearing being designed to support an upper glass substrate, the upper glass substrate being designed to overlap the lower glass substrate. - a plurality of longitudinal profiles designed to be positioned in parallel with one another, each longitudinal profile comprising a central groove and two lateral grooves (51, 52), - corner fixing parts designed to cooperate with the central groove of the longitudinal profiles, each corner fixing part being designed to hold the corners of two adjacent lateral glass substrates on the same longitudinal profile and to fix said adjacent lateral glass substrates simultaneously, characterised in that the fixing and sealing system further comprises transverse bars perpendicular to the plurality of longitudinal profiles, each transverse bar being fixed to two adjacent longitudinal profiles and each transverse bar comprising a stepped surface with a lower bearing and an upper bearing, the lower bearing being designed to support a lower glass substrate and the upper bearing being designed to support an upper glass substrate, the upper glass substrate being designed to overlap the lower glass substrate.
A slurry composition, comprising: a binder composition comprising a urethane based organic binder, a melamine based organic binder, a silane coupling agent, and a solvent; and superabsorbent polymer particles, wherein the amount of melamine based organic binder is the range of 5-10 wt%, based on the total weight of the binder composition.
Automobile column produced by hot-forming and press-hardening, wherein the automobile column has at least two regions of different strength after press-hardening and a region of a first type has bainite as the primary structure component and this has a stretchability A50 of between 10% and 30% and a region of a second type has martensite as the primary structure component, and a transition region between the region of a first type and the region of a second type is smaller than 80 mm, characterised in that the region of a first type is constructed as a flange, a connecting flange and/or an outside edge of the automobile column and in the region of a second type bainite is present as an additional structure component and that the yield strength and/or tensile strength in the transition region decreases or increases with a gradient of more than 200 N/mm 2 per 10 mm.
Device for logging the tensile force in a tensioning belt with - a holding device for holding a spring element (11, 23) - an elastically deformable spring element (11, 23) that is held by the holding device and on which a section of the tensioning belt can absorb forces and elastically deform the spring element (11, 23), wherein the ends (13a, 13b) of the spring element (11, 23) are brought closer to one another when the tensile force increases and - an electronic sensor unit with - a sensor arrangement that measures the excursion of the spring element and generates a data signal, - an emitter for transmitting the data signal to a receiving unit, - a microprocessor that is connected with the sensor arrangement and the emitter and - an energy source for supplying the electronic sensor unit with current and - an electronic receiving unit for receiving the data signal from the emitter with - a receiver - a display for displaying the data signal and - a microprocessor that is connected with the receiver and the display, wherein a specific data signal can be generated by the sensor arrangement for each specific excursion of the spring element and the specific data signals can be detected at any time in the electronic receiving unit, wherein the specific data signals can be stored and called up at any time in the electronic receiving unit. - a holding device for holding a spring element (11, 23) - an elastically deformable spring element (11, 23) that is held by the holding device and on which a section of the tensioning belt can absorb forces and elastically deform the spring element (11, 23), wherein the ends (13a, 13b) of the spring element (11, 23) are brought closer to one another when the tensile force increases and - an electronic sensor unit with - a sensor arrangement that measures the excursion of the spring element and generates a data signal, - an emitter for transmitting the data signal to a receiving unit, - a microprocessor that is connected with the sensor arrangement and the emitter and - an energy source for supplying the electronic sensor unit with current and - an electronic receiving unit for receiving the data signal from the emitter with - a receiver - a display for displaying the data signal and - a microprocessor that is connected with the receiver and the display, - a sensor arrangement that measures the excursion of the spring element and generates a data signal, - an emitter for transmitting the data signal to a receiving unit, - a microprocessor that is connected with the sensor arrangement and the emitter and - an energy source for supplying the electronic sensor unit with current and - an electronic receiving unit for receiving the data signal from the emitter with - a receiver - a display for displaying the data signal and - a microprocessor that is connected with the receiver and the display, - a receiver - a display for displaying the data signal and - a microprocessor that is connected with the receiver and the display,
A refrigerator comprising: a storage container provided in a storage chamber, a decorative member provided in the storage container, the decorative member configured to generate light refraction and guide a movement of condensate condensed in the storage container, and configured to be capable of displaying humidity inside the storage container according to the movement degree of condensate, the decorative member having a path part formed in a capillary tube shape to generate a capillary phenomenon for moving the condensate wherein in that the path parts are arranged vertically, spaced apart a predetermined distance from each other in parallel, characterized in that the decorative member is provided to display humidity inside the storage container according to the height of condensate lifted upward along the path parts. a storage container provided in a storage chamber, a decorative member provided in the storage container, the decorative member configured to generate light refraction and guide a movement of condensate condensed in the storage container, and configured to be capable of displaying humidity inside the storage container according to the movement degree of condensate, the decorative member having a path part formed in a capillary tube shape to generate a capillary phenomenon for moving the condensate wherein in that the path parts are arranged vertically, spaced apart a predetermined distance from each other in parallel, characterized in that the decorative member is provided to display humidity inside the storage container according to the height of condensate lifted upward along the path parts.
A kit for the isolation of stem cells, comprising: (a) a first bag containing a predetermined quantity of a plasma blood volume expander; (b) a second bag having an interior surface coated with a cell-adherent surface layer and containing a predetermined quantity of growth medium, said cell-adherent surface layer comprising poly-L-lysine; and (c) sterile connection means for transferring the contents of the first bag to the second bag. (a) a first bag containing a predetermined quantity of a plasma blood volume expander; (b) a second bag having an interior surface coated with a cell-adherent surface layer and containing a predetermined quantity of growth medium, said cell-adherent surface layer comprising poly-L-lysine; and (c) sterile connection means for transferring the contents of the first bag to the second bag.
A press forming method for forming a press forming part, the press forming part including: a top portion; a side wall portion continuous from the top portion, the side wall portion having a recessed portion in which a bottom edge, which is an end on an opposite side of the top portion in a side view, is recessed toward the top portion; and a flange portion formed outward on the bottom edge of the side wall portion, the recessed portion including a first curved portion continuous with the bottom edge being a portion having a large wall depth, an inclined side portion continuous with the first curved portion, a second curved portion continuous with the inclined side portion, and a recessed side portion having a small wall depth, arranged in order from the bottom edge being a portion having a large wall depth, the flange portion being formed such that the flange portion formed in the first curved portion becomes a shrink flange while the flange portion formed in the second curved portion becomes a stretch flange, characterized by a first forming step of forming a preformed part, the preformed part including the side wall portion, the flange portion formed in the bottom edge being a portion having a large wall depth and a torsional shape portion formed in the inclined side portion continuous from the flange portion to reach the second curved portion; and a second forming step of further processing the preformed part formed in the first forming step, including processes of forming the torsional shape portion into the flange portion and forming the flange portion in the second curved portion continuous from the inclined side portion and in the recessed side portion having a small wall depth so as to achieve formation of a target shape. a first forming step of forming a preformed part, the preformed part including the side wall portion, the flange portion formed in the bottom edge being a portion having a large wall depth and a torsional shape portion formed in the inclined side portion continuous from the flange portion to reach the second curved portion; and a second forming step of further processing the preformed part formed in the first forming step, including processes of forming the torsional shape portion into the flange portion and forming the flange portion in the second curved portion continuous from the inclined side portion and in the recessed side portion having a small wall depth so as to achieve formation of a target shape.
A positive displacement pump comprising: - a pump body defining a pump chamber and a drive side, - a rotor configured to transfer fluid from at least one first environment to at least one second environment through at least one inlet for a suction duct and at least one outlet for a discharge duct, - a driven wheel fixedly connected to said rotor and a driving wheel connectable to a drive member and coupled with said driven wheel, said driven wheel being configured to rotate said rotor, said positive displacement pump being characterized in that the driving wheel is placed inside said driven wheel, in that said driving wheel has teeth formed on an outer surface thereof and said driven wheel has teeth formed on an inner surface thereof, and in that the teeth of the driven wheel and the teeth of the driving wheel achieve a reducing gear ratio, so as to reduce the power dissipated during the pump operation, the movement of the rotor being constrained by a guide formed in the pump body, so that the driving wheel is placed outside the pump body and the driven wheel is placed on the drive side of the pump body, facing towards the outside of the pump body, so that the pump can be placed, depending on the available space, in a plurality of possible positions along a circumference centred on a rotation axis of the driving wheel, said circumference having a radius equal to the distance between a rotation axis of the driven wheel and the rotation axis of the driving wheel. - a pump body defining a pump chamber and a drive side, - a rotor configured to transfer fluid from at least one first environment to at least one second environment through at least one inlet for a suction duct and at least one outlet for a discharge duct, - a driven wheel fixedly connected to said rotor and a driving wheel connectable to a drive member and coupled with said driven wheel, said driven wheel being configured to rotate said rotor,
A current collector used for an electrode of a secondary battery, comprising: a laminate structure in which a resin layer and a metal layer formed on both surfaces of the resin layer are laminated, wherein a surface of the metal layer comprises a rough surface part that is provided with a plurality of protruding parts (62b1) and a plurality of recessed parts (62b2), on the rough surface part, a resin coat layer is formed, and among the plurality of protruding parts (62b1), at least one part of the protruding parts (62b1) comprises an exposed part (62b3) that is exposed from the resin coat layer. a laminate structure in which a resin layer and a metal layer formed on both surfaces of the resin layer are laminated, wherein a surface of the metal layer comprises a rough surface part that is provided with a plurality of protruding parts (62b1) and a plurality of recessed parts (62b2), on the rough surface part, a resin coat layer is formed, and among the plurality of protruding parts (62b1), at least one part of the protruding parts (62b1) comprises an exposed part (62b3) that is exposed from the resin coat layer.
Pivot arbor for a timepiece movement comprising at least one pivot made of a first non-magnetic metal material at at least one of the ends thereof in order to limit the sensitivity thereof to magnetic fields, characterised in that at least the outer surface of said pivot is coated with a first layer of a second material, made of chemical NiB or chemical NiP, having a thickness comprised between 1 μm and 5 μm, and preferentially between 1 μm and 2 μm, and in that at least the first layer of the second material is at least partially coated with a second layer of a third material selected from the group comprising gold, silver, copper, and their alloys, the second layer of the third material having a thickness comprised between 0.1 μm and 1 μm, preferably between 0.1 μm and 0.5 μm.
A porous current collector (8a, 9a), suitable for provision in at least one of a first current collector and a second current collector in a fuel cell including a solid electrolyte layer, a first electrode layer on one side of the solid electrolyte layer, a second electrode layer on the other side, the first current collector on one side of the first electrode layer, and the second current collector on the other side of the second electrode layer, the porous current collector (8a, 9a) comprising: a nickel porous base material, which is a porous base material having continuous pores and in which an alloy layer containing nickel and tin (Sn) is formed at least on a surface of the porous base material; and a silver layer formed on a surface of the alloy layer containing nickel and tin, wherein: a solid solution layer of nickel, tin, and silver is formed at and near an interface between the alloy layer and the silver layer at least at an operating temperature of the fuel cell; the nickel porous base material has a three-dimensional network structure; the three-dimensional network structure includes an integrally continuous skeleton having an outer shell and a core containing one or both of a hollow material and a conductive material; and the silver layer is formed on a surface of the outer shell and the silver layer covers an entire surface of the nickel porous base material. a nickel porous base material, which is a porous base material having continuous pores and in which an alloy layer containing nickel and tin (Sn) is formed at least on a surface of the porous base material; and a silver layer formed on a surface of the alloy layer containing nickel and tin, a solid solution layer of nickel, tin, and silver is formed at and near an interface between the alloy layer and the silver layer at least at an operating temperature of the fuel cell; the nickel porous base material has a three-dimensional network structure; the three-dimensional network structure includes an integrally continuous skeleton having an outer shell and a core containing one or both of a hollow material and a conductive material; and the silver layer is formed on a surface of the outer shell and the silver layer covers an entire surface of the nickel porous base material.
A hot melt adhesive composition, comprising: 2% to 30% of a petrolatum; 1% to 30% of a styrenic block copolymer; 1% to 30% of a polyolefin polymer; 20% to 50% of a tackifier or blend of tackifiers; 0% to 25% of a wax; 0% to 3% of an antioxidant or stabilizer; and 0% to 3% of auxiliary additives. 2% to 30% of a petrolatum; 1% to 30% of a styrenic block copolymer; 1% to 30% of a polyolefin polymer; 20% to 50% of a tackifier or blend of tackifiers; 0% to 25% of a wax; 0% to 3% of an antioxidant or stabilizer; and 0% to 3% of auxiliary additives.
A transmission system for a multi-plate friction clutch, comprising at least the following components: - a plurality of axial guiding devices (3, 4) each arranged between two friction plates (5, 6, 7) that move axially relative to one another, wherein at least one first axial guiding device is arranged between an axially fixed counter plate and a first axially movable pressure plate, and wherein at least one further axial guiding device is arranged between an axially movable pressure plate or the axially fixed counter plate and a further axially movable pressure plate; - at least one transmission device with at least one transmission receiver fastened to a pressure plate, wherein a transmission device is assigned to an axial guiding device, wherein the assigned axial guiding device is arranged integrated into a multi-plate friction clutch between respectively different friction plates (5, 7), wherein furthermore, it comprises at least one adjustment device, by means of which the relative position between the at least one transmission device and a friction plate (5, 6) or the assigned axial guiding device, or between a friction plate (5, 6) and the axial guiding device can be adjusted, characterised in that the adjustment device comprises at least one first flange for receiving a transmission receiver of the at least one transmission device and/or at least one second flange for receiving the assigned axial guiding device, wherein the at least one flange (18, 19) can be adapted using at least one of the following measures: - milling a contact surface of the receptacle; - cold deforming at least the contact surface of the receptacle; - passing through a bolt-shaped transmission receiver; and - pressing a transmission receiver. - a plurality of axial guiding devices (3, 4) each arranged between two friction plates (5, 6, 7) that move axially relative to one another, wherein at least one first axial guiding device is arranged between an axially fixed counter plate and a first axially movable pressure plate, and wherein at least one further axial guiding device is arranged between an axially movable pressure plate or the axially fixed counter plate and a further axially movable pressure plate; - at least one transmission device with at least one transmission receiver fastened to a pressure plate, wherein a transmission device is assigned to an axial guiding device, wherein the assigned axial guiding device is arranged integrated into a multi-plate friction clutch between respectively different friction plates (5, 7), - milling a contact surface of the receptacle; - cold deforming at least the contact surface of the receptacle; - passing through a bolt-shaped transmission receiver; and - pressing a transmission receiver.
Agricultural vehicle comprising at least: - a left and a right crawler track (7, 8) each having a crawler belt for transmitting a drive torque to a ground, - a control device, wherein the control device is configured to calculate a rotational resistance of the crawler tracks (7, 8), characterised in that the control device determines a compensating yaw moment which counteracts the rotational resistance of the crawler tracks (7, 8), wherein the agricultural vehicle has a torque distribution means which is configured and controllable in such a way that it distributes a drive torque between the left and right crawler tracks (7, 8) so that the crawler tracks (7, 8) generate the compensating yaw moment, wherein the torque distribution means is designed as a compensating transmission. - a left and a right crawler track (7, 8) each having a crawler belt for transmitting a drive torque to a ground, - a control device, wherein the control device is configured to calculate a rotational resistance of the crawler tracks (7, 8), characterised in that the control device determines a compensating yaw moment which counteracts the rotational resistance of the crawler tracks (7, 8), wherein the agricultural vehicle has a torque distribution means which is configured and controllable in such a way that it distributes a drive torque between the left and right crawler tracks (7, 8) so that the crawler tracks (7, 8) generate the compensating yaw moment, wherein the torque distribution means is designed as a compensating transmission.
Oven, especially domestic oven, having a cooking cavity and means for illuminating the cavity, wherein the means for illuminating comprise a housing for receiving a lamp, wherein at least a part of the housing has a glass element which is transparent for the light emitted by the lamp, characterized in that the glass element is covered by a heat reflecting layer, wherein the housing is made from sheet metal, wherein the housing has a substantial cuboidal shape and is inserted into an opening which is machined into a wall which is delimiting the cavity.