A manually-activated reduced pressure treatment system comprising: a reduced pressure manifold configured to be placed adjacent a tissue site; and a manually-compressible pump in fluid communication with the reduced pressure manifold to deliver a reduced pressure to the tissue site, the manually-compressible pump comprising: a flexible and compressible side wall; first and second end caps connected at opposite ends of the side wall to form an inner chamber defined by the side wall and the end caps, the inner chamber having a volume that varies from a maximum value when the side wall is in an uncompressed position to a minimum value when the side wall is in a compressed position; a connection port disposed in one of the first and second end caps to allow fluid communication between the inner chamber and the reduced pressure manifold; a one-way valve disposed in one of the first end cap, the second end cap, and the side wall to allow fluid expulsion from the inner chamber; a hydrophobic filter in communication with the one-way valve to prevent liquids from exiting the inner chamber through the one-way valve; and an odor filter in communication with the one-way valve to eliminate odors associated with gases expelled through the one-way valve. a reduced pressure manifold configured to be placed adjacent a tissue site; and a manually-compressible pump in fluid communication with the reduced pressure manifold to deliver a reduced pressure to the tissue site, the manually-compressible pump comprising: a flexible and compressible side wall; first and second end caps connected at opposite ends of the side wall to form an inner chamber defined by the side wall and the end caps, the inner chamber having a volume that varies from a maximum value when the side wall is in an uncompressed position to a minimum value when the side wall is in a compressed position; a connection port disposed in one of the first and second end caps to allow fluid communication between the inner chamber and the reduced pressure manifold; a one-way valve disposed in one of the first end cap, the second end cap, and the side wall to allow fluid expulsion from the inner chamber; a hydrophobic filter in communication with the one-way valve to prevent liquids from exiting the inner chamber through the one-way valve; and an odor filter in communication with the one-way valve to eliminate odors associated with gases expelled through the one-way valve. a flexible and compressible side wall; first and second end caps connected at opposite ends of the side wall to form an inner chamber defined by the side wall and the end caps, the inner chamber having a volume that varies from a maximum value when the side wall is in an uncompressed position to a minimum value when the side wall is in a compressed position; a connection port disposed in one of the first and second end caps to allow fluid communication between the inner chamber and the reduced pressure manifold; a one-way valve disposed in one of the first end cap, the second end cap, and the side wall to allow fluid expulsion from the inner chamber; a hydrophobic filter in communication with the one-way valve to prevent liquids from exiting the inner chamber through the one-way valve; and an odor filter in communication with the one-way valve to eliminate odors associated with gases expelled through the one-way valve.