A method for scrambling sequence configuration, comprising: when a user equipment, UE, receives a transmission signal from a base station via an enhanced control channel, obtaining a search space corresponding to the enhanced control channel, wherein the search space comprises a UE-specific search space and a common search space; performing a scrambling initialization operation according to the search space, and determining an initialization value of a scrambling sequence; determining the scrambling sequence according to the initialization value of the scrambling sequence; and performing a descrambling operation to the transmission signal according to the scrambling sequence, and obtaining information in the transmission signal wherein the performing a scrambling initialization operation according to the search space comprises: if the search space is the UE-specific search space, performing a UE-specific scrambling initialization operation, wherein the UE-specific scrambling initialization refers to that initial generation of the scrambling depends on a first parameter of the UE; if the search space is the common search space, performing a transmission point-specific scrambling initialization operation, wherein the transmission point-specific initialization refers to that initial generation of the scrambling depends on a second parameter of the transmission point; and wherein the first parameter comprises a cell radio network temporary identifier, C-RNTI. when a user equipment, UE, receives a transmission signal from a base station via an enhanced control channel, obtaining a search space corresponding to the enhanced control channel, wherein the search space comprises a UE-specific search space and a common search space; performing a scrambling initialization operation according to the search space, and determining an initialization value of a scrambling sequence; determining the scrambling sequence according to the initialization value of the scrambling sequence; and performing a descrambling operation to the transmission signal according to the scrambling sequence, and obtaining information in the transmission signal wherein the performing a scrambling initialization operation according to the search space comprises: if the search space is the UE-specific search space, performing a UE-specific scrambling initialization operation, wherein the UE-specific scrambling initialization refers to that initial generation of the scrambling depends on a first parameter of the UE; if the search space is the common search space, performing a transmission point-specific scrambling initialization operation, wherein the transmission point-specific initialization refers to that initial generation of the scrambling depends on a second parameter of the transmission point; and if the search space is the UE-specific search space, performing a UE-specific scrambling initialization operation, wherein the UE-specific scrambling initialization refers to that initial generation of the scrambling depends on a first parameter of the UE; if the search space is the common search space, performing a transmission point-specific scrambling initialization operation, wherein the transmission point-specific initialization refers to that initial generation of the scrambling depends on a second parameter of the transmission point; and wherein the first parameter comprises a cell radio network temporary identifier, C-RNTI.