A pipette tip dispensing device, comprising: a) a housing (22, 64); b) a distal barrier plate (28, 70) in connection with the housing; c) a plurality of nested pipette tip columns, each of which nested pipette tip columns is aligned with a channel (32, 76) in the distal barrier plate and the columns are arranged in an array; each pipette tip comprises a proximal end comprising a proximal portion and a rim, which distal barrier plate comprises: a plurality of channels, wherein each of which channels has a diameter larger than the widest portion of a pipette tip, wherein the widest portion of a pipette tip is a major outer transverse dimension of rim or a largest outer diameter of the proximal portion; a substantially flat top surface, and a substantially flat bottom surface comprising a plurality of tails around the channels; wherein: (i) the tails extend in a nearly perpendicular orientation from the flat bottom surface, and (ii) the tails around each channel contact and deflect outwards against the proximal portion of a pipette tip when a pipette tip is dispensed and passes by the tails, thereby imparting a frictional force on the pipette tip when it is dispensed characterized in that the plurality of channels comprises a first subset of channels and a second subset of channels, wherein the first-subset of channels comprises tails that apply a frictional force to the pipette tips and the second subset of channels comprises tails that apply a different frictional force to the pipette tips, wherein differences in the shape, size, length, thickness, width, rigidity, texture, or angle of the tails affect the frictional force applied to pipette tips when they are dispensed. a) a housing (22, 64); b) a distal barrier plate (28, 70) in connection with the housing; c) a plurality of nested pipette tip columns, each of which nested pipette tip columns is aligned with a channel (32, 76) in the distal barrier plate and the columns are arranged in an array; each pipette tip comprises a proximal end comprising a proximal portion and a rim, which distal barrier plate comprises: a plurality of channels, wherein each of which channels has a diameter larger than the widest portion of a pipette tip, wherein the widest portion of a pipette tip is a major outer transverse dimension of rim or a largest outer diameter of the proximal portion; a substantially flat top surface, and a substantially flat bottom surface comprising a plurality of tails around the channels; wherein: (i) the tails extend in a nearly perpendicular orientation from the flat bottom surface, and (ii) the tails around each channel contact and deflect outwards against the proximal portion of a pipette tip when a pipette tip is dispensed and passes by the tails, thereby imparting a frictional force on the pipette tip when it is dispensed characterized in that the plurality of channels comprises a first subset of channels and a second subset of channels, wherein the first-subset of channels comprises tails that apply a frictional force to the pipette tips and the second subset of channels comprises tails that apply a different frictional force to the pipette tips, wherein differences in the shape, size, length, thickness, width, rigidity, texture, or angle of the tails affect the frictional force applied to pipette tips when they are dispensed. each pipette tip comprises a proximal end comprising a proximal portion and a rim, which distal barrier plate comprises: a plurality of channels, wherein each of which channels has a diameter larger than the widest portion of a pipette tip, wherein the widest portion of a pipette tip is a major outer transverse dimension of rim or a largest outer diameter of the proximal portion; a substantially flat top surface, and a substantially flat bottom surface comprising a plurality of tails around the channels; wherein: (i) the tails extend in a nearly perpendicular orientation from the flat bottom surface, and (ii) the tails around each channel contact and deflect outwards against the proximal portion of a pipette tip when a pipette tip is dispensed and passes by the tails, thereby imparting a frictional force on the pipette tip when it is dispensed characterized in that the plurality of channels comprises a first subset of channels and a second subset of channels, wherein the first-subset of channels comprises tails that apply a frictional force to the pipette tips and the second subset of channels comprises tails that apply a different frictional force to the pipette tips, wherein differences in the shape, size, length, thickness, width, rigidity, texture, or angle of the tails affect the frictional force applied to pipette tips when they are dispensed.