mhurhangee/ep-ind-claims huggingface dataset:
Method for preparing a 2,2-difluoroethylamine of the formula in which 2,2-difluoroethylamine of the formula is reacted with a halide of the formula where Hal is chlorine, bromine or iodine, in the presence of diisopropylethylamine, where, in the formulae and A is a pyrid-2-yl, pyrid-4-yl or pyrid-3-yl radical each of which may be substituted in the 6-position by fluorine, chlorine, bromine, methyl, trifluoromethyl or trifluoromethoxy or is pyridazin-3-yl which may be substituted in the 6-position by chlorine or methyl, or is a pyrazin-3-yl, 2-chloropyrazin-5-yl or 1,3-thiazol-5-yl radical which may respectively be substituted in the 2-position by chlorine or methyl, or is a pyrimidinyl, pyrazolyl, thiophenyl, oxazolyl, isoxazolyl, 1,2,4-oxadiazolyl, isothiazolyl, 1,2,4-triazolyl or 1,2,5-thiadiazolyl radical which may be substituted by fluorine, chlorine, bromine, cyano, nitro, C 1 -C 4 -alkyl optionally substituted by fluorine and/or chlorine, C 1 -C 3 -alkylthio optionally subsituted by fluorine and/or chlorine, or C 1 -C 3 -alkylsulphonyl optionally substituted by fluorine and/or chlorine, or is a pyrid-3-yl of the following formula where X is fluorine, chlorine, bromine, iodine, C 1 -C 6 -alkyl or C 1 -C 6 -haloalkyl and Y is fluorine, chlorine, bromine, iodine, C 1 -C 6 -alkyl, C 1 -C 6 -haloalkyl, C 1 -C 6 -haloalkoxy, azido or cyano. A is a pyrid-2-yl, pyrid-4-yl or pyrid-3-yl radical each of which may be substituted in the 6-position by fluorine, chlorine, bromine, methyl, trifluoromethyl or trifluoromethoxy or is pyridazin-3-yl which may be substituted in the 6-position by chlorine or methyl, or is a pyrazin-3-yl, 2-chloropyrazin-5-yl or 1,3-thiazol-5-yl radical which may respectively be substituted in the 2-position by chlorine or methyl, or is a pyrimidinyl, pyrazolyl, thiophenyl, oxazolyl, isoxazolyl, 1,2,4-oxadiazolyl, isothiazolyl, 1,2,4-triazolyl or 1,2,5-thiadiazolyl radical which may be substituted by fluorine, chlorine, bromine, cyano, nitro, C 1 -C 4 -alkyl optionally substituted by fluorine and/or chlorine, C 1 -C 3 -alkylthio optionally subsituted by fluorine and/or chlorine, or C 1 -C 3 -alkylsulphonyl optionally substituted by fluorine and/or chlorine, or is a pyrid-3-yl of the following formula X is fluorine, chlorine, bromine, iodine, C 1 -C 6 -alkyl or C 1 -C 6 -haloalkyl and Y is fluorine, chlorine, bromine, iodine, C 1 -C 6 -alkyl, C 1 -C 6 -haloalkyl, C 1 -C 6 -haloalkoxy, azido or cyano.
A method in a remote unit, the method comprising: receiving, while in connected mode, an indication to monitor parameters in idle mode, said parameters comprising parameters of failures during a connection establishment from idle mode; after receiving the indication to monitor parameters, transitioning from the connected mode to the idle mode; monitoring the parameters in the idle mode; transmitting a request to a first base station to establish a connection; in response to not receiving a correct response to establish the connection from the first base station: performing a cell reselection resulting in selection of a second base station; and transmitting a failure report to the second base station to identify the first base station as a rogue base station, wherein the failure report comprises the parameters gathered during the connection establishment failure with the first base station and the parameters gathered in idle mode. receiving, while in connected mode, an indication to monitor parameters in idle mode, said parameters comprising parameters of failures during a connection establishment from idle mode; after receiving the indication to monitor parameters, transitioning from the connected mode to the idle mode; monitoring the parameters in the idle mode; transmitting a request to a first base station to establish a connection; in response to not receiving a correct response to establish the connection from the first base station: performing a cell reselection resulting in selection of a second base station; and transmitting a failure report to the second base station to identify the first base station as a rogue base station, wherein the failure report comprises the parameters gathered during the connection establishment failure with the first base station and the parameters gathered in idle mode. performing a cell reselection resulting in selection of a second base station; and transmitting a failure report to the second base station to identify the first base station as a rogue base station, wherein the failure report comprises the parameters gathered during the connection establishment failure with the first base station and the parameters gathered in idle mode.
A novel foot force acquisition apparatus, wherein the novel foot force acquisition apparatus comprises a first connecting rod, a pressure signal acquisition board, a second connecting rod rotatably connected with the first connecting rod, and an air tube; an end portion of the second connecting rod is fixedly provided with an elastic foot pad, the elastic foot pad is provided with an air chamber, one end of the air tube is communicated with the air chamber, and the other end is connected to the pressure signal acquisition board; the elastic foot pad is configured to contact the ground to deform and squeeze the air chamber, and the pressure signal acquisition board is configured to measure the change of the internal pressure value of the air chamber through the air tube, so as to realize the signal acquisition of the force on the elastic foot pad, wherein the first connecting rod or the second connecting rod is provided with a mounting groove or a mounting cavity for placing the air tube, characterized in that the air tube is provided along the first connecting rod and the second connecting rod, and the air tube spans a rotating joint formed by the first connecting rod and the second connecting rod and an elastic member, which is a tension spring, a compression spring, a torsion spring, elastic silica gel or elastic plastic, and which is capable of pulling the air tube, is provided in the first connecting rod or the second connecting rod, one end of the elastic member is fixedly connected with the first connecting rod or the second connecting rod, and the other end is fixedly connected with the air tube, so that a portion of the air tube located at the rotating joint is always kept in a tensioned state during the rotation of the second connecting rod relative to the first connecting rod.
A method of mapping cardiac activation, comprising: receiving, at an electroanatomical mapping system, electrophysiological data from a plurality of electrodes carried by a multi-electrode catheter, the plurality of electrodes defining a plurality of cliques; and for each clique of the plurality of cliques, the electroanatomical mapping system executing a process comprising: identifying an integral (900a, 900b, 900c) of an omnipolar electrogram (800a, 800b, 800c) for the clique having a best morphological match to a unipolar electrogram (500a, 500b, 500c, 700) for the clique; defining an orientation of the omnipolar electrogram (800a, 800b, 800c) for the clique having the best morphological match to the unipolar electrogram (500a, 500b, 500c) for the clique as an activation direction for the clique; and computing a conduction velocity magnitude for the clique using the integral (900a, 900b, 900c) of the omnipolar electrogram (800a, 800b, 800c) for the clique and the unipolar electrogram (500a, 500b, 500c, 700) for the clique, thereby determining a cardiac activation map. receiving, at an electroanatomical mapping system, electrophysiological data from a plurality of electrodes carried by a multi-electrode catheter, the plurality of electrodes defining a plurality of cliques; and for each clique of the plurality of cliques, the electroanatomical mapping system executing a process comprising: identifying an integral (900a, 900b, 900c) of an omnipolar electrogram (800a, 800b, 800c) for the clique having a best morphological match to a unipolar electrogram (500a, 500b, 500c, 700) for the clique; defining an orientation of the omnipolar electrogram (800a, 800b, 800c) for the clique having the best morphological match to the unipolar electrogram (500a, 500b, 500c) for the clique as an activation direction for the clique; and computing a conduction velocity magnitude for the clique using the integral (900a, 900b, 900c) of the omnipolar electrogram (800a, 800b, 800c) for the clique and the unipolar electrogram (500a, 500b, 500c, 700) for the clique, identifying an integral (900a, 900b, 900c) of an omnipolar electrogram (800a, 800b, 800c) for the clique having a best morphological match to a unipolar electrogram (500a, 500b, 500c, 700) for the clique; defining an orientation of the omnipolar electrogram (800a, 800b, 800c) for the clique having the best morphological match to the unipolar electrogram (500a, 500b, 500c) for the clique as an activation direction for the clique; and computing a conduction velocity magnitude for the clique using the integral (900a, 900b, 900c) of the omnipolar electrogram (800a, 800b, 800c) for the clique and the unipolar electrogram (500a, 500b, 500c, 700) for the clique, thereby determining a cardiac activation map.
A frictional propulsion device, for an omni-directional vehicle, comprising: a frame; a main wheel including an annular core member having a laterally extending central axial center line and a plurality of driven rollers each rotatably supported on the annular core member about a tangential line of the annular core member; a support shaft supported by the frame and extending laterally across a hollow interior of the main wheel; a pair of drive disks rotatably supported by the support shaft on either side of the main wheel, the drive disks being individually rotatable around a central axial line common to the support shaft; and a plurality of drive rollers arranged along a peripheral part of each drive disk and each rotatably supported by the drive disk about a rotational center line at an angle with respect to both a tangential line of the drive disk and the rotational center line of the drive disk, at least part of the drive rollers engaging the driven rollers of the main wheel; wherein a diameter of a drive side contact circle defined by points on the drive disk at which the drive rollers contact the driven rollers is smaller than a diameter of a driven side contact circle defined by the points on the main wheel at which the driven rollers contact the drive rollers, and the drive disks are vertically offset relative to the main wheel so that only those drive rollers adjoining the main wheel are in contact with the driven rollers. a frame; a main wheel including an annular core member having a laterally extending central axial center line and a plurality of driven rollers each rotatably supported on the annular core member about a tangential line of the annular core member; a support shaft supported by the frame and extending laterally across a hollow interior of the main wheel; a pair of drive disks rotatably supported by the support shaft on either side of the main wheel, the drive disks being individually rotatable around a central axial line common to the support shaft; and a plurality of drive rollers arranged along a peripheral part of each drive disk and each rotatably supported by the drive disk about a rotational center line at an angle with respect to both a tangential line of the drive disk and the rotational center line of the drive disk, at least part of the drive rollers engaging the driven rollers of the main wheel; wherein a diameter of a drive side contact circle defined by points on the drive disk at which the drive rollers contact the driven rollers is smaller than a diameter of a driven side contact circle defined by the points on the main wheel at which the driven rollers contact the drive rollers, and the drive disks are vertically offset relative to the main wheel so that only those drive rollers adjoining the main wheel are in contact with the driven rollers.
A cloud gateway device, comprising: a device interface component adapted to receive (1502;1602) data from one or more controller tags of an industrial controller associated with an industrial automation system; and a cloud interface component adapted to couple the cloud gateway device to a cloud platform and send the data to the cloud platform, wherein the one or more controller tags and a uniform resource locator, URL, of the cloud platform are defined in a configuration file associated with the cloud gateway device; wherein the cloud interface component is adapted to send the data to the cloud platform at an upload frequency controlled by a cloud-based application from the cloud platform; and wherein the cloud interface component is adapted to download an updated version of the configuration file in response to a determination that the configuration file stored locally at the cloud gateway device is out of date. a device interface component adapted to receive (1502;1602) data from one or more controller tags of an industrial controller associated with an industrial automation system; and a cloud interface component adapted to couple the cloud gateway device to a cloud platform and send the data to the cloud platform, wherein the one or more controller tags and a uniform resource locator, URL, of the cloud platform are defined in a configuration file associated with the cloud gateway device; wherein the cloud interface component is adapted to send the data to the cloud platform at an upload frequency controlled by a cloud-based application from the cloud platform; and wherein the cloud interface component is adapted to download an updated version of the configuration file in response to a determination that the configuration file stored locally at the cloud gateway device is out of date. wherein the one or more controller tags and a uniform resource locator, URL, of the cloud platform are defined in a configuration file associated with the cloud gateway device; wherein the cloud interface component is adapted to send the data to the cloud platform at an upload frequency controlled by a cloud-based application from the cloud platform; and wherein the cloud interface component is adapted to download an updated version of the configuration file in response to a determination that the configuration file stored locally at the cloud gateway device is out of date.
A pharmaceutical composition, comprising: (a) 1 mg/ml-120 mg/ml anti-SOST antibody or antigen-binding fragment thereof; (b) 5 mM-30 mM acetate buffer; (c) 45 mg/ml-90 mg/ml trehalose; (d) 0.02 mg/ml-0.8 mg/ml polysorbate 80; and (e) 4.5 mM-20 mM calcium salt; wherein the pH of the pharmaceutical composition is from 4.8 to 5.5; wherein the anti-SOST antibody or antigen binding fragment thereof comprises HCDR1, HCDR2 and HCDR3 sequences as shown in SEQ ID NO: 3, SEQ ID NO: 9, and SEQ ID NO: 5, respectively, and LCDR1, LCDR2 and LCDR3 sequences as shown in SEQ ID NO: 6, SEQ ID NO: 7, and SEQ ID NO: 8, respectively; and wherein the antigen-binding fragment is a Fab fragment, a Fab' fragment, a F(ab')2 fragment or a scFv fragment. (a) 1 mg/ml-120 mg/ml anti-SOST antibody or antigen-binding fragment thereof; (b) 5 mM-30 mM acetate buffer; (c) 45 mg/ml-90 mg/ml trehalose; (d) 0.02 mg/ml-0.8 mg/ml polysorbate 80; and (e) 4.5 mM-20 mM calcium salt; wherein the pH of the pharmaceutical composition is from 4.8 to 5.5; wherein the anti-SOST antibody or antigen binding fragment thereof comprises HCDR1, HCDR2 and HCDR3 sequences as shown in SEQ ID NO: 3, SEQ ID NO: 9, and SEQ ID NO: 5, respectively, and LCDR1, LCDR2 and LCDR3 sequences as shown in SEQ ID NO: 6, SEQ ID NO: 7, and SEQ ID NO: 8, respectively; and wherein the antigen-binding fragment is a Fab fragment, a Fab' fragment, a F(ab')2 fragment or a scFv fragment.
A coupler (300c, d, f, g) comprising: a drive hub (304c, d, f, g) having a first end (308c, d, f, g) and a second end (312c, d, f, g) including a recess (336c, d, f, g) configured to receive a driveshaft (222c, d, f, g) of a driver; where the recess has a circular cross-sectional shape and is defined by a cylindrical wall; and where the first end of the drive hub is configured to be coupled to an intraosseous device to resist rotation of the IO device relative to the drive hub; and where the second end of the drive hub is configured such that if the driveshaft is inserted into the recess, an interference fit between the drive hub and the driveshaft will resist rotation of the drive hub relative to the driveshaft. a drive hub (304c, d, f, g) having a first end (308c, d, f, g) and a second end (312c, d, f, g) including a recess (336c, d, f, g) configured to receive a driveshaft (222c, d, f, g) of a driver; where the recess has a circular cross-sectional shape and is defined by a cylindrical wall; and where the first end of the drive hub is configured to be coupled to an intraosseous device to resist rotation of the IO device relative to the drive hub; and where the second end of the drive hub is configured such that if the driveshaft is inserted into the recess, an interference fit between the drive hub and the driveshaft will resist rotation of the drive hub relative to the driveshaft.
Modular heat exchange device for placing into radiator module or modules, comprising two metallic or polymeric plates which include between said plates at least one resilient element for moving said plates apart, so that the plates contact said module or modules, when placed into said radiator module or modules, an electric resistor, and an electric connector, characterized in that the resilient element comprises one spring or two springs.
A transgenic insect-controlling cotton plant, or cell, part, or seed, each comprising in its genome an elite event EE-GH6, said elite event EE-GH6 comprising a foreign DNA comprising a coding sequence of a modified cry2Ae gene operably linked to a Rubisco small subunit transit peptide under the control of a Cauliflower Mosaic Virus 35S promoter and nucleotide sequences spanning the joining regions between plant derived DNA sequences and foreign DNA sequences having the nucleotide sequence of SEQ ID 1 or SEQ ID 11 and SEQ ID 2; wherein said elite event EE-GH6 is comprised in reference seed deposited at the ATCC under deposit number PTA-8398, wherein the presence of said elite event EE-GH6 is characterized by insect resistance as well as glufosinate tolerance.
Device for decontaminating surfaces comprising one or more toxic products comprising at least one hydroblasting head comprising a closed volume for drawing a mixture of water, toxic products and residue, the hydroblasting head being fed by a high pressure unit and connected to a vacuum source comprising a low pressure source connected to a cyclone head mounted on a container which collects water containing toxic products and residues of the support, a first filtration system consisting of a filtering press whose input is fed with water containing toxic products collected in said container and whose output feeds a buffer tank wherein the water from the first filtration being used to filter particles less than or equal to 5 μm.
An electrochemical measurement device configured to electrochemically measure a specimen with using a measuring liquid, the electrochemical measurement device comprising: a first well configured to have the specimen placed therein and have the measuring liquid injected thereto; a wall having an inner wall surface forming the first well, the wall surrounding the first well; a first working electrode contacting the first well, the first working electrode being configured to have an electric potential applied thereto; and a leakage detector that detects a leakage of the measuring liquid, characterized in that, the first working electrode, the wall and the leakage detector are arranged such that the first working electrode is surrounded by the wall defining the first well and by the leakage detector (14, 141, 142), wherein a lower end of the inner wall surface is disposed between the first working electrode and the leakage detector, wherein the leakage detector includes a leakage detecting electrode for detecting a leakage current. a first well configured to have the specimen placed therein and have the measuring liquid injected thereto; a wall having an inner wall surface forming the first well, the wall surrounding the first well; a first working electrode contacting the first well, the first working electrode being configured to have an electric potential applied thereto; and a leakage detector that detects a leakage of the measuring liquid, characterized in that, the first working electrode, the wall and the leakage detector are arranged such that the first working electrode is surrounded by the wall defining the first well and by the leakage detector (14, 141, 142), wherein a lower end of the inner wall surface is disposed between the first working electrode and the leakage detector, wherein the leakage detector includes a leakage detecting electrode for detecting a leakage current.
Method for producing hollow-chamber profiles, - which have a plurality of hollow chambers, an outer visible surface and an inner visible surface, - in which a thermoplastic is extruded to form the hollow-chamber profile, calibrated, cooled and heat-treated, characterized in that the heat treatment takes place by heating the outer visible surface and the inner visible surface at least in subregions in such a way that the outer visible surface and the inner visible surface reach a temperature in heated subregions above the Vicat softening temperature of the thermoplastic and the predominant part of the other profile regions has a temperature below the Vicat softening temperature. - which have a plurality of hollow chambers, an outer visible surface and an inner visible surface, - in which a thermoplastic is extruded to form the hollow-chamber profile, calibrated, cooled and heat-treated,