A method of manufacturing a patient interface for sealed delivery of a flow of air at a continuously positive pressure with respect to ambient air pressure to an entrance to a patient's airways, the method comprising: collecting anthropometric data of a patient's face including relaxed state data collected using contactless methods or contact method, and deformed state data by simulating, based on a pressure level in the patient interface, with simulation software, the deformed state data based on the relaxed state data and known tissue properties, the known tissue properties including any one from a group consisting of: soft tissue thickness, modulus data based on force, deflection, modulus and thickness, soft tissue thickness ratio information, body mass index; wherein collected anthropometric data comprise the relaxed state data and the deformed state data from the simulation; identifying anticipated considerations from the collected anthropometric data for use of the patient interface, wherein identifying anticipated considerations comprises identifying specific areas of the face with respect to at least one of pressure sensitivity, pressure compliance, shear sensitivity and shear compliance; processing the collected anthropometric data to provide a transformed data set based on the anticipated considerations, wherein processing the collected anthropometric data accounts for areas of sealing region on the patient's face that: (i) require different levels of sealing force, (ii) are more sensitive to pressure or (iii) are more likely to have a leak in that location due to complex facial geometry, the transformed data set corresponding to at least one customised patient interface component (3100, 11001, 3300); and providing the data for modelling at least one patient interface component (3100, 11001, 3300) based on the transformed data set. collecting anthropometric data of a patient's face including relaxed state data collected using contactless methods or contact method, and deformed state data by simulating, based on a pressure level in the patient interface, with simulation software, the deformed state data based on the relaxed state data and known tissue properties, the known tissue properties including any one from a group consisting of: soft tissue thickness, modulus data based on force, deflection, modulus and thickness, soft tissue thickness ratio information, body mass index; relaxed state data collected using contactless methods or contact method, and deformed state data by simulating, based on a pressure level in the patient interface, with simulation software, the deformed state data based on the relaxed state data and known tissue properties, the known tissue properties including any one from a group consisting of: soft tissue thickness, modulus data based on force, deflection, modulus and thickness, soft tissue thickness ratio information, body mass index; wherein collected anthropometric data comprise the relaxed state data and the deformed state data from the simulation; identifying anticipated considerations from the collected anthropometric data for use of the patient interface, wherein identifying anticipated considerations comprises identifying specific areas of the face with respect to at least one of pressure sensitivity, pressure compliance, shear sensitivity and shear compliance; processing the collected anthropometric data to provide a transformed data set based on the anticipated considerations, wherein processing the collected anthropometric data accounts for areas of sealing region on the patient's face that: (i) require different levels of sealing force, (ii) are more sensitive to pressure or (iii) are more likely to have a leak in that location due to complex facial geometry, the transformed data set corresponding to at least one customised patient interface component (3100, 11001, 3300); and providing the data for modelling at least one patient interface component (3100, 11001, 3300) based on the transformed data set.