A compound of formula: A-L 1 -Y-L 2 -R-B wherein A is a cyclic group having the following formula: wherein G 3 is CH or N when the dashed line represents a double bond, or CH 2, NH or O when the dashed line represents a single bond; C 1 represents the atoms necessary to form an aliphatic or aromatic six-membered cycle optionally comprising one or more heteroatom selected from nitrogen atom and oxygen atom, said cycle being optionally substituted by one or more substituent selected from the group consisting of halogen atom, (C 1-3)alkyl group, cyano group, oxo group (=O), and (C 1-3)alkoxy group; L 1 is σ bond, or (C 1-3)alkylenyl group, optionally substituted with hydroxy group; Y is a ring selected from the group consisting of piperidinyl, piperazinyl, pyrrolidinyl, 1-3 cyclobutyl, 1-3 cyclopentyl, 1-2 cyclopropyl, azetidinyl, azabicyclo-octyl, morpholinyl and cyclohexyl ring, said ring being optionally substituted by one or more substituent selected from the group consisting of hydroxy group, (C 1-3)alkylenyl-OH group, (C 1-3)alkylenyl-O-(C 1-3)alkyl group, (C 1-3)alkylenyl-CONR'R" group, and CONR'R" group, wherein R' and R" are hydrogen atom or (C 1-3)alkyl; L 2 is σ bond, -(C 1 - 3)alkylenyl- group, NR'" group, NR'"-(C 1-3)alkylenyl group, (C 1-3)alkylenyl-NR'" group, NR'"-(C 1-3)alkylenyl-NR'" group, or (C 1-3)alkylenyl-NR'"-(C 1-3)alkylenyl group, said group being optionally substituted with a hydroxy group, wherein R'" is hydrogen, (C 1-3)alkyl, (C 1-3)alkylenyl-OH, (C 1-3)alkylenyl-O-(C 1-3)alkyl, or (C 1-3)alkylenyl-CONR'R", wherein R' and R" are hydrogen atom or (C 1-3)alkyl; R is σ bond or heterocyclic ring, aliphatic or aromatic, having 5 members containing one or more nitrogen atoms, optionally substituted with CH 2 OH, CH 2 CN, CN or CONR'R", wherein R' and R" are hydrogen atom or (C 1-3)alkyl; and B is cyclic group having the following formula: wherein G 6 is CH or N; R 2 is hydrogen atom or halogen atom; and addition salts with pharmaceutically acceptable organic or inorganic acids or basis, enantiomers, N-oxides and quaternary ammonium salts of said compound of formula. A is a cyclic group having the following formula: wherein G 3 is CH or N when the dashed line represents a double bond, or CH 2, NH or O when the dashed line represents a single bond; C 1 represents the atoms necessary to form an aliphatic or aromatic six-membered cycle optionally comprising one or more heteroatom selected from nitrogen atom and oxygen atom, said cycle being optionally substituted by one or more substituent selected from the group consisting of halogen atom, (C 1-3)alkyl group, cyano group, oxo group (=O), and (C 1-3)alkoxy group; G 3 is CH or N when the dashed line represents a double bond, or CH 2, NH or O when the dashed line represents a single bond; C 1 represents the atoms necessary to form an aliphatic or aromatic six-membered cycle optionally comprising one or more heteroatom selected from nitrogen atom and oxygen atom, said cycle being optionally substituted by one or more substituent selected from the group consisting of halogen atom, (C 1-3)alkyl group, cyano group, oxo group (=O), and (C 1-3)alkoxy group; L 1 is σ bond, or (C 1-3)alkylenyl group, optionally substituted with hydroxy group; Y is a ring selected from the group consisting of piperidinyl, piperazinyl, pyrrolidinyl, 1-3 cyclobutyl, 1-3 cyclopentyl, 1-2 cyclopropyl, azetidinyl, azabicyclo-octyl, morpholinyl and cyclohexyl ring, said ring being optionally substituted by one or more substituent selected from the group consisting of hydroxy group, (C 1-3)alkylenyl-OH group, (C 1-3)alkylenyl-O-(C 1-3)alkyl group, (C 1-3)alkylenyl-CONR'R" group, and CONR'R" group, wherein R' and R" are hydrogen atom or (C 1-3)alkyl; L 2 is σ bond, -(C 1 - 3)alkylenyl- group, NR'" group, NR'"-(C 1-3)alkylenyl group, (C 1-3)alkylenyl-NR'" group, NR'"-(C 1-3)alkylenyl-NR'" group, or (C 1-3)alkylenyl-NR'"-(C 1-3)alkylenyl group, said group being optionally substituted with a hydroxy group, wherein R'" is hydrogen, (C 1-3)alkyl, (C 1-3)alkylenyl-OH, (C 1-3)alkylenyl-O-(C 1-3)alkyl, or (C 1-3)alkylenyl-CONR'R", wherein R' and R" are hydrogen atom or (C 1-3)alkyl; R is σ bond or heterocyclic ring, aliphatic or aromatic, having 5 members containing one or more nitrogen atoms, optionally substituted with CH 2 OH, CH 2 CN, CN or CONR'R", wherein R' and R" are hydrogen atom or (C 1-3)alkyl; and B is cyclic group having the following formula: wherein G 6 is CH or N; R 2 is hydrogen atom or halogen atom; G 6 is CH or N; R 2 is hydrogen atom or halogen atom; and addition salts with pharmaceutically acceptable organic or inorganic acids or basis, enantiomers, N-oxides and quaternary ammonium salts of said compound of formula.