mhurhangee/ep-ind-claims huggingface dataset:
A method of preparing a composition, such as a gel, the composition comprising a crosslinked first polymer, optionally a second polymer, the second polymer may be crosslinked or non-crosslinked, and water, wherein the first and the second polymer are selected from a polysaccharide, comprising at least steps (i), (ii) and (iv) and, optionally step (iii): (i) crosslinking a mixture comprising the first polymer and water; (ii) subsequent to the crosslinking in step (i), terminating the crosslinking; (iii) optionally blending the product obtained in step (ii) with the second polymer; (iv) subjecting the product obtained in step (ii) or step (iii) to dialysis; wherein said dialysis step (iv) comprises steps (iv.1) to (iv.3): (iv.1) extruding the product obtained in step (ii) or step (iii) through a first sieve and subsequently extruding the extruded product from the first sieve through a second sieve, wherein the mesh size of the second sieve is less than the mesh size of the first sieve; or extruding the product obtained in step (ii) or step (iii) through a first sieve, and subsequently extruding the extruded product from the first sieve through a second sieve, and subsequently extruding the extruded product from the second sieve through a third sieve, wherein the mesh size of the second sieve is less than the mesh size of the first sieve, and the mesh size of the third sieve is less than the mesh size of the second sieve; (iv.2) filling the product obtained in step (iv.1) into a dialysis membrane; (iv.3) subjecting the filled membrane obtained in step (iv.2) to a dialysis solution and wherein the first sieve has a mesh size in the range of from 200 to 600 μm; and the second sieve has a mesh size in the range of from 100 to 400 μm; and the third sieve has a mesh size in the range of from 50 to 300 μm. (i) crosslinking a mixture comprising the first polymer and water; (ii) subsequent to the crosslinking in step (i), terminating the crosslinking; (iii) optionally blending the product obtained in step (ii) with the second polymer; (iv) subjecting the product obtained in step (ii) or step (iii) to dialysis; (iv.1) extruding the product obtained in step (ii) or step (iii) through a first sieve and subsequently extruding the extruded product from the first sieve through a second sieve, wherein the mesh size of the second sieve is less than the mesh size of the first sieve; or extruding the product obtained in step (ii) or step (iii) through a first sieve, and subsequently extruding the extruded product from the first sieve through a second sieve, and subsequently extruding the extruded product from the second sieve through a third sieve, wherein the mesh size of the second sieve is less than the mesh size of the first sieve, and the mesh size of the third sieve is less than the mesh size of the second sieve; (iv.2) filling the product obtained in step (iv.1) into a dialysis membrane; (iv.3) subjecting the filled membrane obtained in step (iv.2) to a dialysis solution and
A combination of an immune checkpoint inhibitor with an agent capable of increasing intra-tumoral ceramide content for use in a method of treating cancer in a subject in need thereof, wherein administration of the combination results in enhanced therapeutic efficacy relative to the administration of the immune checkpoint inhibitor alone, wherein the immune checkpoint inhibitor is an antibody selected from the group consisting of anti-CTLA4 antibodies, anti-PD-1 antibodies, anti-PD-L1 antibodies, anti-PD-L2 antibodies anti-TIM-3 antibodies, anti-LAG3 antibodies, anti-B7H3 antibodies, anti-B7H4 antibodies, anti-BTLA antibodies, and anti-B7H6 antibodies, and wherein the agent capable of increasing intra-tumoral ceramide content is a polynucleotide encoding for a neutral sphingomyelinase 2 (nSMase 2) polypeptide.
A first wireless transmit / receive unit, WTRU,, configured for multiple phase cooperative data transmission, the first WTRU comprising: a receiver configured to receive, by the first WTRU from an evolved Node B, eNB,, cooperative set configuration information including a cooperating set specific radio network identifier, C-RNTI; the receiver further configured to receive, by the first WTRU from the eNB,, a resource assignment for a first data transmission corresponding to a sharing phase; a transmitter configured to transmit the first data transmission during the sharing phase, using resources indicated in the received resource assignment and the received C-RNTI and a first redundancy version; on a condition the first data transmission is successfully received by at least a second WTRU (606, 608) and the first data transmission is not successfully received by the eNB,, the transmitter is configured to transmit a second data transmission, in cooperation with the second WTRU, (606, 608), during a cooperative transmission phase using a second redundancy version; and on a condition the first data transmission is not successfully received by the second WTRU (606, 608) and not successfully received by the eNB,, the transmitter is configured to transmit a third data transmission during the cooperative transmission phase using a third redundancy version; wherein the first redundancy version and the second redundancy version and the third redundancy version are different redundancy versions. a receiver configured to receive, by the first WTRU from an evolved Node B, eNB,, cooperative set configuration information including a cooperating set specific radio network identifier, C-RNTI; the receiver further configured to receive, by the first WTRU from the eNB,, a resource assignment for a first data transmission corresponding to a sharing phase; a transmitter configured to transmit the first data transmission during the sharing phase, using resources indicated in the received resource assignment and the received C-RNTI and a first redundancy version; on a condition the first data transmission is successfully received by at least a second WTRU (606, 608) and the first data transmission is not successfully received by the eNB,, the transmitter is configured to transmit a second data transmission, in cooperation with the second WTRU, (606, 608), during a cooperative transmission phase using a second redundancy version; and on a condition the first data transmission is not successfully received by the second WTRU (606, 608) and not successfully received by the eNB,, the transmitter is configured to transmit a third data transmission during the cooperative transmission phase using a third redundancy version; wherein the first redundancy version and the second redundancy version and the third redundancy version are different redundancy versions.
A perforated plate for an application device (18, 19) for the application of a fluid, in particular a coating agent, a paint, a sealant, a glue, a functional layer or a separating agent, to a component, in particular to a motor vehicle body component, with a) a plurality of through-holes for passing the coating agent through, each with a1) a hole inlet opening on the side of the perforated plate that is located upstream, and a2) a hole exit opening on the side of the perforated plate that is located downstream, and a3) a three-dimensional structuring on the side of the perforated plate that is located downstream, a4) wherein the structuring comprises a pipe stub which protrudes from the side of the perforated plate that is located downstream and into which the through-hole transitions, in order to reduce a wetting surface (6, 8) at the hole exit opening, b) wherein the surface density of the through-holes, the distance between the through-holes and the internal cross-section of the through-holes are dimensioned such that the coating-agent jets emerging from the through-holes, after impinging on the component, form a coherent coating-agent film, characterised in c) that the through-holes have different internal cross-sections, and d) that the perforated plate in the region with the through-holes has a thickness of less than 1 mm. a) a plurality of through-holes for passing the coating agent through, each with a1) a hole inlet opening on the side of the perforated plate that is located upstream, and a2) a hole exit opening on the side of the perforated plate that is located downstream, and a3) a three-dimensional structuring on the side of the perforated plate that is located downstream, a4) wherein the structuring comprises a pipe stub which protrudes from the side of the perforated plate that is located downstream and into which the through-hole transitions, in order to reduce a wetting surface (6, 8) at the hole exit opening, a1) a hole inlet opening on the side of the perforated plate that is located upstream, and a2) a hole exit opening on the side of the perforated plate that is located downstream, and a3) a three-dimensional structuring on the side of the perforated plate that is located downstream, a4) wherein the structuring comprises a pipe stub which protrudes from the side of the perforated plate that is located downstream and into which the through-hole transitions, in order to reduce a wetting surface (6, 8) at the hole exit opening, b) wherein the surface density of the through-holes, the distance between the through-holes and the internal cross-section of the through-holes are dimensioned such that the coating-agent jets emerging from the through-holes, after impinging on the component, form a coherent coating-agent film, characterised in c) that the through-holes have different internal cross-sections, and d) that the perforated plate in the region with the through-holes has a thickness of less than 1 mm.
A conversion kit for converting a conveyor frame to accommodate wearstrips forming a carryway for a conveyor belt, comprising: a plurality of straight brackets, each straight bracket extending from a first side to a second side and a plurality of curved brackets, each curved bracket having a curved base extending from a first side to a second side, wherein the straight brackets are mounted at first and second ends of a spine and the curved brackets are mounted at intermediate points on the spine, said conversion kit characterised by each straight bracket having a plurality of first open slots in an upper edge, a first flange extending up from the first side and having a second open slot extending perpendicular to the first open slots and a second flange extending up from the second side and having a third open slot extending parallel to the second open slot; and by each curved brackets (520, 530) having a plurality of fourth open slots in an upper edge of the curved base, a third flange extending perpendicular to the upper edge at the first side and having a fifth open slot facing inwards and extending perpendicular to the third flange and a fourth flange extending perpendicular to the upper edge at the second edge and having a sixth open slot facing inwards extending perpendicular to the fourth flange, wherein the first, second, third, fourth, fifth and sixth open slots (550, 581) are configured to receive wearstrips. a plurality of straight brackets, each straight bracket extending from a first side to a second side and a plurality of curved brackets, each curved bracket having a curved base extending from a first side to a second side, wherein the straight brackets are mounted at first and second ends of a spine and the curved brackets are mounted at intermediate points on the spine, said conversion kit characterised by each straight bracket having a plurality of first open slots in an upper edge, a first flange extending up from the first side and having a second open slot extending perpendicular to the first open slots and a second flange extending up from the second side and having a third open slot extending parallel to the second open slot; and by each curved brackets (520, 530) having a plurality of fourth open slots in an upper edge of the curved base, a third flange extending perpendicular to the upper edge at the first side and having a fifth open slot facing inwards and extending perpendicular to the third flange and a fourth flange extending perpendicular to the upper edge at the second edge and having a sixth open slot facing inwards extending perpendicular to the fourth flange, wherein the first, second, third, fourth, fifth and sixth open slots (550, 581) are configured to receive wearstrips.
Irrigation device with a capillary water transport line containing a strand of fibrous material and formed for contacting the fibrous material at a discharge end of the water transport line with a ground substrate carrying at least one plant, wherein at the discharge end of the water transport line a dimensionally stable ground spike with a handle part and a plug part, which is designed for insertion into a ground substrate, is arranged, characterized in that the fibrous material is fixed to the plug part with a in working position with the ground substrate contactable portion (E21, E22), and in that the strand of fibrous material extends in the water transport direction from the handle part with a portion in the direction of a tip of the plug part and after deflection in a further portion back to the handle part.
A compound of the following Formula or a pharmaceutically acceptable salt thereof, wherein the Formula is: wherein R 3 R 4 R 5 R 9 L 1 L 4 Y H H -SO 2 - H -CH 2 - -NHCO- CH H H -SO 2 - H -C(CH 2 CH 2)- -NHCO- CH H H -CH - H -CH 2 - -NHCO- CH H H -CH - H -C(CH 2 CH 2)- -NHCO- CH
A method for predicting the outcome of a cancer in a patient comprising a step consisting of determining the expression level of a miRNA cluster in a tumor sample obtained from said patient, wherein said miRNA cluster comprises miR.494.
Rail vehicle drive bogie comprising two wheelsets each comprising a pair of wheels, each wheel set extending along a wheel set axis, said wheelsets being connected to each other by a chassis comprising at least two longitudinal members extending substantially parallel to a longitudinal axis and resting on wheel set boxes (14, 14') of each wheel set, the said axleboxes (14, 14') being arranged between the wheels of the said wheel set, at least one motor fixed to the chassis and extending between the wheels of the wheel set and driving the rotation of the said wheel set via a coupling and a gearbox, one of the axleboxes housing the gearbox of the motor, the motor being able to rotate about a motor axis, characterised in that the axis of the motor is located at an altitude (h) lower than an altitude of the axis of the wheel set, the altitude being taken along a vertical axis perpendicular to the longitudinal axis and to the axle axis from a horizontal plane perpendicular to the vertical axis and tangent to the wheel at the bottom of the bogie.
A method for producing a packaged food product portion (10, 100), comprising the following steps: - providing a cup defining an inner area for receiving the food product, - cold pouring, at a temperature below 50°C, the food product into the receiving area of the cup, - covering the food product using a lid arranged such that flaps of the cup, which are thermally conducting, extend toward the outside of the lid after the covering step, - folding the flaps on an outer face of the lid opposite the receiving area, and - heat-sealing the flaps on the outer face, characterized in that the lid is thermally insulating. - providing a cup defining an inner area for receiving the food product, - cold pouring, at a temperature below 50°C, the food product into the receiving area of the cup, - covering the food product using a lid arranged such that flaps of the cup, which are thermally conducting, extend toward the outside of the lid after the covering step, - folding the flaps on an outer face of the lid opposite the receiving area, and - heat-sealing the flaps on the outer face,
A device for driving a motor, the device comprising: a main housing for accommodating a circuit module therein, wherein a top of the main housing is partially opened to define an open portion; an input/output cover coupled to the main housing so as to occupy the open portion; and an auxiliary housing coupled to the main housing at an vertical side face of the main housing, wherein at least one first coupling hole is defined in the vertical side face of the main housing, wherein the auxiliary housing has at least one second coupling hole defined at a position corresponding to a position of the at least one first coupling hole, characterized in that the main housing has a strength-enhancing vertical groove upwardly opened and defined in the vertical side face, wherein the main housing further includes a strength-enhancing piece of a shape corresponding to a shape of the strength-enhancing groove, wherein the strength-enhancing piece has at least one third coupling hole defined in a position thereof corresponding to the position of the at least one first coupling hole, and wherein at least one screw passes through the at least one first coupling hole, the at least one second coupling hole, and the at least one third coupling hole. a main housing for accommodating a circuit module therein, wherein a top of the main housing is partially opened to define an open portion; an input/output cover coupled to the main housing so as to occupy the open portion; and an auxiliary housing coupled to the main housing at an vertical side face of the main housing, wherein at least one first coupling hole is defined in the vertical side face of the main housing, wherein the auxiliary housing has at least one second coupling hole defined at a position corresponding to a position of the at least one first coupling hole, characterized in that the main housing has a strength-enhancing vertical groove upwardly opened and defined in the vertical side face, wherein the main housing further includes a strength-enhancing piece of a shape corresponding to a shape of the strength-enhancing groove, wherein the strength-enhancing piece has at least one third coupling hole defined in a position thereof corresponding to the position of the at least one first coupling hole, and wherein at least one screw passes through the at least one first coupling hole, the at least one second coupling hole, and the at least one third coupling hole.
A hot gas path component (100, 200) of a turbine system, the HGP component (100, 200) comprising: a body (110, 210) including: a forward end (120, 220); an aft end (122, 222) positioned opposite the forward end (120, 220); an inner portion (132, 232) positioned adjacent a hot gas flow path of the turbine system, the inner portion (132, 232) extending between the forward end (120, 220) and aft end (122, 222); an outer portion (134, 234) formed radially opposite the inner portion (132, 232) and extending between the forward end (120, 220) and aft end (122, 222); a plurality of nozzles (146, 246) extending through the outer portion (134, 234); and an intermediate portion (136, 236) formed between the inner portion (132, 232) and the outer portion (134, 234); characterized by a plurality of venturies (148, 248) extending through the intermediate portion (136, 236), the plurality of venturies (148, 248) in fluid communication with the plurality of nozzles (146, 246); wherein the plurality of nozzles (146, 246) are each radially and/or concentrically aligned with a corresponding venturi of the plurality of venturies (148, 248). a forward end (120, 220); an aft end (122, 222) positioned opposite the forward end (120, 220); an inner portion (132, 232) positioned adjacent a hot gas flow path of the turbine system, the inner portion (132, 232) extending between the forward end (120, 220) and aft end (122, 222); an outer portion (134, 234) formed radially opposite the inner portion (132, 232) and extending between the forward end (120, 220) and aft end (122, 222); a plurality of nozzles (146, 246) extending through the outer portion (134, 234); and an intermediate portion (136, 236) formed between the inner portion (132, 232) and the outer portion (134, 234); characterized by a plurality of venturies (148, 248) extending through the intermediate portion (136, 236), the plurality of venturies (148, 248) in fluid communication with the plurality of nozzles (146, 246); wherein the plurality of nozzles (146, 246) are each radially and/or concentrically aligned with a corresponding venturi of the plurality of venturies (148, 248).
A polyester film provided with a layer (a P layer) that contains a crystalline polyester and also contains plate-like particles each having an aspect ratio of 2 or more and/or needle-like particles each having an aspect ratio of 2 or more, wherein the plate-like particle having an aspect ratio of 2 or more and the needle-like particle having an aspect ratio of 2 or more are collectively called particle, wherein the crystalline polyester is a polyester containing a dicarboxylic acid constituent and a diol constituent as main constituents, and is also a resin having a ΔHm value (amount of heat for crystal melting) of not lower than 15 J/g, the P layer is stretched in at least one axial direction and the Young's modulus of the polyester film is 2 GPa or more and the values of Wb and V/Wb are 10 or more and 1 or less, respectively, wherein Wb (% by mass) represents the total content of the plate-like particles each having an aspect ratio of 2 or more and the needle-like particles each having an aspect ratio of 2 or more in the P layer, and V (% by volume) represents the porosity in the P layer, wherein the plate-like particle having an aspect ratio of 2 or more and the needle-like particle having an aspect ratio of 2 or more have on their surfaces a substituent reactive with the crystalline polyester (hereinafter, the substituent is called reactive substituent (a)), and the amount of the reactive substituent (a) on a unit surface area of the particle is not smaller than 0.2 × 10 -6 mol/m 2 and not greater than 1.4 × 10 -4 mol/m 2.
Saponified ethylene-vinyl ester-based copolymer pellet containing a boron compound. wherein a total amount of boron in the saponified ethylene-vinyl ester-based copolymer pellet is from 10 to 1000 ppm, characterized in that an amount of boron contained in a surface portion of the saponified ethylene-vinyl ester-based copolymer pellet is 1.7 ppm or less, wherein the boron amount contained in the surface portion of the saponified ethylene-vinyl ester-based copolymer pellet is determined by measuring a solution obtained by dipping 4 g of the saponified ethylene-vinyl ester-based copolymer pellet in 20 ml of methanol at 30 °C for 6 hours with an inductively coupled plasma mass spectrometer; and a weight ratio of the boron contained in the surface portion to the total amount of boron in the saponified ethylene-vinyl ester-based copolymer pellet is 1.38×10 -2 or less.
An external structuring system for liquid and gel-form detergents comprising by weight percentage: a) from 2% to 10 % of crystals of a glyceride or a mixture thereof having a melting temperature of from 40 °C to 100 °C; b) from 2% to 20% of pH adjusting agent or a mixture thereof; c) from 5% to 50% of an anionic surfactant or a mixture thereof; and d) from greater than 1% to equal or less than 2,5% of an organic non-aminofunctional alcohol selected from the group consisting of ethanol, propanol, butanol, isopropanol, 1,2-propanediol, 1,3-propanediol, diethylglycol and mixtures thereof. a) from 2% to 10 % of crystals of a glyceride or a mixture thereof having a melting temperature of from 40 °C to 100 °C; b) from 2% to 20% of pH adjusting agent or a mixture thereof; c) from 5% to 50% of an anionic surfactant or a mixture thereof; and d) from greater than 1% to equal or less than 2,5% of an organic non-aminofunctional alcohol selected from the group consisting of ethanol, propanol, butanol, isopropanol, 1,2-propanediol, 1,3-propanediol, diethylglycol and mixtures thereof.
A biomaterial engineered to display a FasL protein, wherein the biomaterial is a hydrogel, wherein the hydrogel comprises a chimeric FasL protein comprising a FasL moiety and a streptavidin or avidin moiety conjugated via biotin to the hydrogel.