A method for detecting Serpula lacrymans contamination in an internal environment, comprising the following steps: a. taking a sample of volatile organic compounds (VOCs) from the internal environment, b. detecting the presence or absence of predetermined VOCs, emitted by Serpula lacrymans, said predetermined VOCs comprising at least one VOC from each of the following three VOC categories:. VOCs emitted by Serpula lacrymans whatever the Serpula lacrymans strain and which do not have other origins;. VOCs emitted by Serpula lacrymans whatever the Serpula lacrymans strain, but which may have other origins;. VOCs emitted only and specifically by certain Serpula lacrymans strains and which do not have other origins; c. determining a presence or an absence of Serpula lacrymans contamination as a function respectively of the presence and of the absence of said predetermined VOCs, taking into consideration each of the following conditions (i), (ii) and (iii): (i). the presence of VOCs of category directly indicates the presence of Serpula lacrymans contamination, while the absence of such VOCs indicates the absence of Serpula lacrymans contamination; and (ii). the presence of VOCs of category does not make it possible to reach a conclusion regarding Serpula lacrymans contamination, whereas the absence of such VOCs indicates the absence of Serpula lacrymans contamination; and (iii). the presence of VOCs of category indicates the presence of Serpula lacrymans contamination, whereas their absence does not make it possible to reach a conclusion regarding the absence of Serpula lacrymans contamination, said method being characterized in that the VOCs of category consist of methyl isocyanide. a. taking a sample of volatile organic compounds (VOCs) from the internal environment, b. detecting the presence or absence of predetermined VOCs, emitted by Serpula lacrymans, said predetermined VOCs comprising at least one VOC from each of the following three VOC categories:. VOCs emitted by Serpula lacrymans whatever the Serpula lacrymans strain and which do not have other origins;. VOCs emitted by Serpula lacrymans whatever the Serpula lacrymans strain, but which may have other origins;. VOCs emitted only and specifically by certain Serpula lacrymans strains and which do not have other origins;. VOCs emitted by Serpula lacrymans whatever the Serpula lacrymans strain and which do not have other origins;. VOCs emitted by Serpula lacrymans whatever the Serpula lacrymans strain, but which may have other origins;. VOCs emitted only and specifically by certain Serpula lacrymans strains and which do not have other origins; c. determining a presence or an absence of Serpula lacrymans contamination as a function respectively of the presence and of the absence of said predetermined VOCs, taking into consideration each of the following conditions (i), (ii) and (iii): (i). the presence of VOCs of category directly indicates the presence of Serpula lacrymans contamination, while the absence of such VOCs indicates the absence of Serpula lacrymans contamination; and (ii). the presence of VOCs of category does not make it possible to reach a conclusion regarding Serpula lacrymans contamination, whereas the absence of such VOCs indicates the absence of Serpula lacrymans contamination; and (iii). the presence of VOCs of category indicates the presence of Serpula lacrymans contamination, whereas their absence does not make it possible to reach a conclusion regarding the absence of Serpula lacrymans contamination, said method being characterized in that the VOCs of category consist of methyl isocyanide. (i). the presence of VOCs of category directly indicates the presence of Serpula lacrymans contamination, while the absence of such VOCs indicates the absence of Serpula lacrymans contamination; and (ii). the presence of VOCs of category does not make it possible to reach a conclusion regarding Serpula lacrymans contamination, whereas the absence of such VOCs indicates the absence of Serpula lacrymans contamination; and (iii). the presence of VOCs of category indicates the presence of Serpula lacrymans contamination, whereas their absence does not make it possible to reach a conclusion regarding the absence of Serpula lacrymans contamination,