mhurhangee/ep-ind-claims huggingface dataset:
A first compound which is a methylthioninium compound in combination with a second compound, which second compound modifies the activity of acetylcholine or glutamate neurotransmitters such as to directly modify synaptic neurotransmission in the brain for use in a method of treatment of an FTLD syndrome in a human subject, which method comprises administering to said subject the first compound in combination with the second compound, wherein the MT compound is a salt of: or a hydrate or solvate thereof, and wherein the second compound is either an acetylcholinesterase inhibitor or an NMDA receptor antagonist.
A cabled yarn comprising: at least two single plied yarns each comprising meta-aramid fibres, para-aramid fibres, cellulose-based fibres, and wool fibres, twisted around a centrally located yarn comprising an Elastolefin fibre, wherein the cabled yarn comprises by weight around 23% meta-aramid fibres, around 4% para-aramid fibres, around 33% cellulose-based fibres, around 33% wool fibres, and around 7% Elastolefin fibres, and wherein the wool fibres have a thickness of around 15.5μm to around 29.5μm.
An agent for use in a method of reducing radiation exposure of a non-cancerous tissue of a patient diagnosed with a cancer, the method comprising the following steps: a) administering a compound comprising a radionuclide to the patient, the compound having affinity for both a cancerous tissue and the non-cancerous tissue; b) allowing a waiting period to pass; and c) administering said agent to the patient, provided that said agent is capable of competing for binding sites on a surface of the non-cancerous tissue and wherein the binding sites have an affinity for both the agent and the compound, preferably wherein the agent displaces bound radionuclide from the binding sites thereby reducing the exposure of the non-cancerous tissue, wherein: the compound is MIP-1555, MIP-1519, MIP-1545, MIP-1427, MIP-1428, MIP-1379, MIP-1072, MIP-1095, MIP-1558, MIP-1405, or MIP-1404; and the agent comprises a phosphinyl containing moiety or is cold MIP-1555, cold MIP-1519, cold MIP-1545, cold MIP-1427, cold MIP-1428, cold MIP-1379, cold MIP-1072, cold MIP-1095, cold MIP-1558, cold MIP-1405, cold MIP-1404, or 2-(phosphonomethyl)pentanedioic acid. a) administering a compound comprising a radionuclide to the patient, the compound having affinity for both a cancerous tissue and the non-cancerous tissue; b) allowing a waiting period to pass; and c) administering said agent to the patient, provided that said agent is capable of competing for binding sites on a surface of the non-cancerous tissue and wherein the binding sites have an affinity for both the agent and the compound, preferably wherein the agent displaces bound radionuclide from the binding sites thereby reducing the exposure of the non-cancerous tissue, wherein: the compound is MIP-1555, MIP-1519, MIP-1545, MIP-1427, MIP-1428, MIP-1379, MIP-1072, MIP-1095, MIP-1558, MIP-1405, or MIP-1404; and the agent comprises a phosphinyl containing moiety or is cold MIP-1555, cold MIP-1519, cold MIP-1545, cold MIP-1427, cold MIP-1428, cold MIP-1379, cold MIP-1072, cold MIP-1095, cold MIP-1558, cold MIP-1405, cold MIP-1404, or 2-(phosphonomethyl)pentanedioic acid. the compound is MIP-1555, MIP-1519, MIP-1545, MIP-1427, MIP-1428, MIP-1379, MIP-1072, MIP-1095, MIP-1558, MIP-1405, or MIP-1404; and the agent comprises a phosphinyl containing moiety or is cold MIP-1555, cold MIP-1519, cold MIP-1545, cold MIP-1427, cold MIP-1428, cold MIP-1379, cold MIP-1072, cold MIP-1095, cold MIP-1558, cold MIP-1405, cold MIP-1404, or 2-(phosphonomethyl)pentanedioic acid.
A switch comprising: a body case; a movable board that is movably disposed in the body case; a movable contact point disposed in the movable board; a fixed contact point (8a to 8d) that is provided in the body case to be fixed thereto and on which a lubricating agent is applied, wherein the movable contact point makes pressure-contact with the fixed contact point (8a to 8d), and is connected to/disconnected from the fixed contact point (8a to 8d) corresponding to a position of the movable contact point changing by moving the movable board; a plurality of grooves with the fixed contact point (8a to 8d)to be arranged along the movement direction of the movable contact point; and a contact portion of the movable contact point is provided with an arc-shaped outer periphery as viewed from a direction vertical to the movement direction of the movable contact point; characterized in that the plurality of grooves are formed in a contact portion of the movable contact point; and the groove is formed across the arc-shaped outer periphery of the contact portion in the movement direction of the movable contact point, and is formed in a spindle shape as viewed from the side of the fixed contact point (8a to 8d). a body case; a movable board that is movably disposed in the body case; a movable contact point disposed in the movable board; a fixed contact point (8a to 8d) that is provided in the body case to be fixed thereto and on which a lubricating agent is applied, wherein the movable contact point makes pressure-contact with the fixed contact point (8a to 8d), and is connected to/disconnected from the fixed contact point (8a to 8d) corresponding to a position of the movable contact point changing by moving the movable board; a plurality of grooves with the fixed contact point (8a to 8d)to be arranged along the movement direction of the movable contact point; and a contact portion of the movable contact point is provided with an arc-shaped outer periphery as viewed from a direction vertical to the movement direction of the movable contact point; characterized in that the plurality of grooves are formed in a contact portion of the movable contact point; and the groove is formed across the arc-shaped outer periphery of the contact portion in the movement direction of the movable contact point, and is formed in a spindle shape as viewed from the side of the fixed contact point (8a to 8d).
A signal comprising video data generated by encoding at least a block in a picture by transforming a residue of the block to obtain transform coefficients, quantizing the transform coefficients to obtain quantized transform coefficients, and entropy coding the quantized transform coefficients, wherein the quantized transform coefficients are encoded using a first flag syntax element to indicate that a current one of the quantized transform coefficients being processed is a last non-zero coefficient for the block in a given scanning order having a value greater than or equal to a specified value, a second flag syntax element to indicate whether a current one of the quantized transform coefficients known to be non-zero has an absolute value of one or larger than one, a sig flag syntax element for indicating whether the current one of the quantized transform coefficients has a non-zero value, a last flag syntax element for indicating whether the current one of the quantized transform coefficients having a non-zero value is a last quantized transform coefficient having the non-zero value in the block in the given scanning order, a level syntax element for indicating an absolute value of the current one of the quantized transform coefficients when the current one of the quantized transform coefficients has the absolute value greater than the specified value, and a sign flag syntax element for indicating a corresponding sign of the current one of the quantized transform coefficients wherein the specified value is selected from among a plurality of values, said selected value is explicitly signaled for the block and wherein the first flag syntax element, the second flag syntax element, the sig flag syntax element, the last flag syntax element, the level syntax element, and the sign flag syntax element are encoded in the given scanning order.
A method for ambient background noise modification, the method comprising: identifying at least one noise present in an environment of a user having a user device, an activity the user is currently engaged in, a physical or emotional state of the user, and a particular goal for the user based on the activity the user is currently engaged in, and the physical or emotional state of the user; determining a target ambient noise to be produced in the environment based at least in part on the identified noise, the activity the user is currently engaged in, the physical or emotional state of the user and the goal for the user, wherein the target ambient noise assists the user in achieving the goal; identifying at least one device associated with the user device to be used to produce the target ambient noise, wherein at least one of the identified devices has at least one fan (1210, 1212); determining sound outputs corresponding to each of the identified devices, wherein a combination of the sound outputs produces an approximation of one or more characteristics of the target ambient noise; and causing the identified devices to produce the determined sound outputs by modulating a speed of the at least one fan associated with the at least one of the identified devices to synthesize the target ambient noise. identifying at least one noise present in an environment of a user having a user device, an activity the user is currently engaged in, a physical or emotional state of the user, and a particular goal for the user based on the activity the user is currently engaged in, and the physical or emotional state of the user; determining a target ambient noise to be produced in the environment based at least in part on the identified noise, the activity the user is currently engaged in, the physical or emotional state of the user and the goal for the user, wherein the target ambient noise assists the user in achieving the goal; identifying at least one device associated with the user device to be used to produce the target ambient noise, wherein at least one of the identified devices has at least one fan (1210, 1212); determining sound outputs corresponding to each of the identified devices, wherein a combination of the sound outputs produces an approximation of one or more characteristics of the target ambient noise; and causing the identified devices to produce the determined sound outputs by modulating a speed of the at least one fan associated with the at least one of the identified devices to synthesize the target ambient noise.
A tool for machining a workpiece, comprising: - a cutting insert with a shank, which extends along a cutting insert longitudinal axis, and with at least one cutting edge, wherein at least a part of the cutting insert is made of a first material; - a tool holder which extends along a holder longitudinal axis and comprises on an end-face end a cutting insert receptacle for receiving the cutting insert shank, wherein the cutting insert receptacle is designed as a cup-shaped recess in the tool holder; characterized in that the tool comprises - an attachment element which is fixedly connected to the cutting insert and extends in a circumferential direction around the cutting insert shank, wherein at least a part of the attachment element is made of a second material which differs from the first material; and in that the tool comprises - a fastening element for fastening the cutting insert on the tool holder, wherein, in a mounted state of the tool, the fastening element contacts the attachment element in order to fasten the cutting insert on the tool holder, wherein the attachment element is shrunk onto the cutting insert shank or is soldered or welded to said cutting insert shank. - a cutting insert with a shank, which extends along a cutting insert longitudinal axis, and with at least one cutting edge, wherein at least a part of the cutting insert is made of a first material; - a tool holder which extends along a holder longitudinal axis and comprises on an end-face end a cutting insert receptacle for receiving the cutting insert shank, wherein the cutting insert receptacle is designed as a cup-shaped recess in the tool holder; characterized in that the tool comprises - an attachment element which is fixedly connected to the cutting insert and extends in a circumferential direction around the cutting insert shank, wherein at least a part of the attachment element is made of a second material which differs from the first material; and in that the tool comprises - a fastening element for fastening the cutting insert on the tool holder, wherein, in a mounted state of the tool, the fastening element contacts the attachment element in order to fasten the cutting insert on the tool holder, wherein the attachment element is shrunk onto the cutting insert shank or is soldered or welded to said cutting insert shank.
A refrigeration appliance, in particular for household use, comprising: - a structure within which at least one compartment (3, 4) is obtained for preserving foodstuffs, which is adapted to be closed by at least one door (3P, 4P); - a beverage dispensing device, said device comprising a tank associated with an inner wall of the structure, wherein said refrigeration appliance comprises a hooking system for hanging the tank on the inner wall of the structure, wherein said hooking system comprises at least one coupling and supporting element adapted to be placed into a cut-out of the inner wall, characterized in that said coupling and supporting element comprises at least one wing adapted to be positioned into an interspace obtained between the inner wall and an outer wall of the structure and then buried into an insulating material, in particular a plastic foam material, so that the coupling and supporting element is firmly positioned and secured in said cut-out of the inner wall. - a structure within which at least one compartment (3, 4) is obtained for preserving foodstuffs, which is adapted to be closed by at least one door (3P, 4P); - a beverage dispensing device, said device comprising a tank associated with an inner wall of the structure,
Speaking valve for laryngectomized or tracheostomized patients, having a cover part, a housing part, and a filter disposed in the housing part, wherein the cover part is disposed at the housing part by means of a latching connection, wherein the housing part comprises a valve seat at its distal end, wherein the cover part comprises a closure part disposed on an inner surface thereof, facing toward the filter, wherein the cover part comprises an elastic material, wherein by means of deformation of at least one region of the cover part, the closure part closes the speaking valve at the end distal to the filter, wherein the closure part has at least one lip element on a lower surface of an outer edge, wherein the lip element interacts with the valve seat upon actuating the speaking valve, wherein the closure part has a circular design, and has a rising surface of a middle part, starting from the lower surface of the outer edge to an attachment region disposed centrally, and the housing part comprises inflow openings at the end distal to the valve seat, which can be locked by means of the closure part upon actuating the speaking valve, and at least one elastic region of the cover part acts as a resetting element.
A method for controlling a vehicle (100, 400), the method comprising: a) predicting (301, 303) the vehicle's path (410; 415a, 415b); and b) detecting a stationary object within the predicted path; characterized by c) determining that an acceleration of the vehicle is greater than a predetermined acceleration threshold (a T); and, d) maintaining the acceleration. a) predicting (301, 303) the vehicle's path (410; 415a, 415b); and b) detecting a stationary object within the predicted path; c) determining that an acceleration of the vehicle is greater than a predetermined acceleration threshold (a T); and, d) maintaining the acceleration.
Sound system, comprising at least one monitoring device, a source device and a transmission medium, wherein the monitoring device is connected with the source device via the transmission medium, wherein the monitoring device is adapted to receive a monitoring signal sent by the source device, wherein the monitoring device is a passive device and adapted to send at least one harmonic of the monitoring signal back to the source device, wherein the monitoring device is adapted as an end of line device connected at an end of the transmission medium, wherein the monitoring signal is transferred via the transmission medium to the monitoring device, wherein the transmission medium is a wire or a cable, wherein the source device comprises a measurement unit for detecting the at least one harmonic sent by the monitoring device, characterised in that the harmonic sent by the monitoring device is the second harmonic. wherein the monitoring device is connected with the source device via the transmission medium, wherein the monitoring device is adapted to receive a monitoring signal sent by the source device, wherein the monitoring device is a passive device and adapted to send at least one harmonic of the monitoring signal back to the source device, wherein the monitoring device is adapted as an end of line device connected at an end of the transmission medium, wherein the monitoring signal is transferred via the transmission medium to the monitoring device, wherein the transmission medium is a wire or a cable, wherein the source device comprises a measurement unit for detecting the at least one harmonic sent by the monitoring device, characterised in that the harmonic sent by the monitoring device is the second harmonic.
Crystalline monohydrate Form A of 2-( -6-(4-chlorophenyl)-1-methyl-4H-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamide, wherein the crystalline form is characterized by at least three x-ray powder diffraction peaks at 2Θ angles selected from 4.73°, 18.09°, 18.48°, 18.80°, 19.70°, and 25.17°.
An inlet for a turbofan engine, the inlet comprising: an inner barrel (402, 502) and an outer barrel (404, 504) configured to form an inlet cowl, the inner barrel including an acoustic panel (406, 506); and the inlet cowl including: a lipskin (410, 510) disposed at a forward end (412, 512) of the inlet cowl; a bulkhead (414, 514) disposed between the inner barrel (402, 502) and the outer barrel (404, 504); and wherein the lipskin comprises a porous panel, a cavity formed between the porous panel and an inner wall of the inlet, and a porous membrane located in the cavity, wherein, in use, ice protection fluid flows from the porous panel onto the acoustic panel; wherein the outer barrel has a length extending aft of an interface between the inner barrel and a fan case connected to the inner barrel such that, in use, an aerodynamic transition is located aft of the interface. an inner barrel (402, 502) and an outer barrel (404, 504) configured to form an inlet cowl, the inner barrel including an acoustic panel (406, 506); and the inlet cowl including: a lipskin (410, 510) disposed at a forward end (412, 512) of the inlet cowl; a bulkhead (414, 514) disposed between the inner barrel (402, 502) and the outer barrel (404, 504); and wherein the lipskin comprises a porous panel, a cavity formed between the porous panel and an inner wall of the inlet, and a porous membrane located in the cavity, wherein, in use, ice protection fluid flows from the porous panel onto the acoustic panel; wherein the outer barrel has a length extending aft of an interface between the inner barrel and a fan case connected to the inner barrel such that, in use, an aerodynamic transition is located aft of the interface. a lipskin (410, 510) disposed at a forward end (412, 512) of the inlet cowl; a bulkhead (414, 514) disposed between the inner barrel (402, 502) and the outer barrel (404, 504); and wherein the lipskin comprises a porous panel, a cavity formed between the porous panel and an inner wall of the inlet, and a porous membrane located in the cavity, wherein, in use, ice protection fluid flows from the porous panel onto the acoustic panel; wherein the outer barrel has a length extending aft of an interface between the inner barrel and a fan case connected to the inner barrel such that, in use, an aerodynamic transition is located aft of the interface.
A multilayer structure comprising: a silicon wafer handle substrate comprising two major, generally parallel surfaces, one of which is a front surface of the silicon wafer handle substrate and the other of which is a back surface of the silicon wafer handle substrate, a circumferential edge joining the front and back surfaces of the silicon wafer handle substrate, and a bulk region between the front and back surfaces of the silicon wafer handle substrate, wherein the silicon wafer handle substrate has a bulk region resistivity between 2000 Ohm-cm and 100,000 Ohm-cm; a charge trapping layer comprising a Group IVA nitride layer in contact with the front surface of the silicon wafer handle substrate, the Group IVA nitride layer selected from the group consisting of carbon nitride, silicon carbon nitride, and a combination thereof and having a thickness of between 200 nanometers and 500 nanometers; a dielectric layer in contact with the Group IVA nitride layer, wherein the dielectric layer is selected from the group consisting of silicon dioxide, silicon nitride, hafnium oxide, titanium oxide, zirconium oxide, lanthanum oxide, barium oxide, and a combination thereof; and a semiconductor device layer in contact with the dielectric layer. a silicon wafer handle substrate comprising two major, generally parallel surfaces, one of which is a front surface of the silicon wafer handle substrate and the other of which is a back surface of the silicon wafer handle substrate, a circumferential edge joining the front and back surfaces of the silicon wafer handle substrate, and a bulk region between the front and back surfaces of the silicon wafer handle substrate, wherein the silicon wafer handle substrate has a bulk region resistivity between 2000 Ohm-cm and 100,000 Ohm-cm; a charge trapping layer comprising a Group IVA nitride layer in contact with the front surface of the silicon wafer handle substrate, the Group IVA nitride layer selected from the group consisting of carbon nitride, silicon carbon nitride, and a combination thereof and having a thickness of between 200 nanometers and 500 nanometers; a dielectric layer in contact with the Group IVA nitride layer, wherein the dielectric layer is selected from the group consisting of silicon dioxide, silicon nitride, hafnium oxide, titanium oxide, zirconium oxide, lanthanum oxide, barium oxide, and a combination thereof; and a semiconductor device layer in contact with the dielectric layer.
A bobbin assembly comprising: - a plurality of winding slots, a plurality of isolation slots and a winding, wherein each of the plurality of winding slots comprises multiple loops of the winding with only one turn per layer; - each of the plurality of isolation slots comprises one single loop of the winding, and each of the isolation slots is adjacent to at least one winding slot of the plurality of winding slots, and each of the winding slots is adjacent to at least one isolation slot of the plurality of isolation slots. - a plurality of winding slots, a plurality of isolation slots and a winding, wherein each of the plurality of winding slots comprises multiple loops of the winding with only one turn per layer; - each of the plurality of isolation slots comprises one single loop of the winding, and each of the isolation slots is adjacent to at least one winding slot of the plurality of winding slots, and each of the winding slots is adjacent to at least one isolation slot of the plurality of isolation slots.