mhurhangee/ep-ind-claims huggingface dataset:
A monolithic antifuse, comprising: a non-planar first conductive terminal disposed over a substrate and having a non-planar top surface, the non-planar first conductive terminal having a high-z portion and a low-z portion, wherein the top surfaces of the high-z and low-z portions form the non-planar top surface of the non-planar first conductive terminal and wherein the high-z portion extends to a greater z-height from the substrate than does the low-z portion; a first dielectric material wrapping around at least one sidewall (230A, 230C) of the low-z portion; and a second conductive terminal disposed over the low-z portion, extending through a least a partial thickness of a second dielectric material, and separated from the first conductive terminal by at least a partial thickness of the first dielectric material. a non-planar first conductive terminal disposed over a substrate and having a non-planar top surface, the non-planar first conductive terminal having a high-z portion and a low-z portion, wherein the top surfaces of the high-z and low-z portions form the non-planar top surface of the non-planar first conductive terminal and wherein the high-z portion extends to a greater z-height from the substrate than does the low-z portion; a first dielectric material wrapping around at least one sidewall (230A, 230C) of the low-z portion; and a second conductive terminal disposed over the low-z portion, extending through a least a partial thickness of a second dielectric material, and separated from the first conductive terminal by at least a partial thickness of the first dielectric material.
A composition comprising (i) a recombinant adeno-associated virus vector comprising an AAV capsid that encapsulates a nucleotide of interest, wherein the AAV capsid comprises a recombinant AAV capsid protein modified to comprise a heterologous epitope, wherein the recombinant AAV capsid protein is derived from an AAV capsid gene modified to express the heterologous epitope; (ii) a multispecific binding molecule comprising (a) an antibody paratope that specifically binds the heterologous epitope; and (b) a retargeting ligand that specifically binds a cell surface protein or marker; and optionally (iii) a pharmaceutically acceptable carrier, wherein the AAV capsid exhibits: - reduced to abolished tropism in the absence of the multispecific binding molecule; and - modified tropism, upon combination with the multispecific binding molecule, compared to a reference AAV capsid, wherein the reference AAV capsid comprises a reference AAV capsid protein that is identical to the recombinant AAV capsid protein but for the lack of the heterologous epitope. (i) a recombinant adeno-associated virus vector comprising an AAV capsid that encapsulates a nucleotide of interest, wherein the AAV capsid comprises a recombinant AAV capsid protein modified to comprise a heterologous epitope, wherein the recombinant AAV capsid protein is derived from an AAV capsid gene modified to express the heterologous epitope; an AAV capsid that encapsulates a nucleotide of interest, wherein the AAV capsid comprises a recombinant AAV capsid protein modified to comprise a heterologous epitope, wherein the recombinant AAV capsid protein is derived from an AAV capsid gene modified to express the heterologous epitope; (ii) a multispecific binding molecule comprising (a) an antibody paratope that specifically binds the heterologous epitope; and (b) a retargeting ligand that specifically binds a cell surface protein or marker; and optionally (a) an antibody paratope that specifically binds the heterologous epitope; and (b) a retargeting ligand that specifically binds a cell surface protein or marker; and optionally (iii) a pharmaceutically acceptable carrier, wherein the AAV capsid exhibits: - reduced to abolished tropism in the absence of the multispecific binding molecule; and - modified tropism, upon combination with the multispecific binding molecule, compared to a reference AAV capsid, wherein the reference AAV capsid comprises a reference AAV capsid protein that is identical to the recombinant AAV capsid protein but for the lack of the heterologous epitope. - reduced to abolished tropism in the absence of the multispecific binding molecule; and - modified tropism, upon combination with the multispecific binding molecule, compared to a reference AAV capsid, wherein the reference AAV capsid comprises a reference AAV capsid protein that is identical to the recombinant AAV capsid protein but for the lack of the heterologous epitope.
A selective shaft engaging assembly comprising: a first shaft; a brake cage being rotatable with the first shaft; a surrounding member extending circumferentially around the brake cage; at least one engagement member coupled to the first shaft; and a braking mechanism configured for selectively applying a force to the brake cage for slowing or preventing rotational movement of the brake cage such that the first shaft rotates relative to the brake cage; wherein the assembly is configured such that when the first shaft rotates relative to the brake cage, said at least one engagement member is urged towards the surrounding member; wherein the assembly comprises at least one biasing member coupling the first shaft to the brake cage such that rotation of the first shaft drives rotation of the brake cage; and wherein the at least one biasing member is configured to bias the circumferential position of the brake cage relative to the first shaft such that the engagement member is located on the surface of the first shaft at a first, radially inward position such that rotation of the first shaft is not prevented, the assembly being characterised in that the brake cage comprises a brake plate and the assembly comprises a moveable member that is selectively movable into or out of contact with the brake plate for providing a braking force on the brake plate and hence to the brake cage. a first shaft; a brake cage being rotatable with the first shaft; a surrounding member extending circumferentially around the brake cage; at least one engagement member coupled to the first shaft; and a braking mechanism configured for selectively applying a force to the brake cage for slowing or preventing rotational movement of the brake cage such that the first shaft rotates relative to the brake cage; wherein the assembly is configured such that when the first shaft rotates relative to the brake cage, said at least one engagement member is urged towards the surrounding member; wherein the assembly comprises at least one biasing member coupling the first shaft to the brake cage such that rotation of the first shaft drives rotation of the brake cage; and wherein the at least one biasing member is configured to bias the circumferential position of the brake cage relative to the first shaft such that the engagement member is located on the surface of the first shaft at a first, radially inward position such that rotation of the first shaft is not prevented, the assembly being characterised in that the brake cage comprises a brake plate and the assembly comprises a moveable member that is selectively movable into or out of contact with the brake plate for providing a braking force on the brake plate and hence to the brake cage.
A prosthetic tissue valve, comprising: a biodegradable base member configured to engage a cardiovascular structure said base member comprising an extracellular matrix composition, said extracellular matrix composition comprising acellular extracellular matrix from a mammalian tissue source, said base member further comprising proximal and distal ends, and plurality of elongated ribbon members that extend from said base member proximal end to said base member distal end, each of said plurality of ribbon members comprising first and second edge regions and proximal and distal ends, said plurality of ribbon members being positioned circumferentially about said base member, wherein said first edge regions of said plurality of ribbon members are positioned proximate said second edge regions of said plurality of ribbon members and form a plurality of contiguous ribbon edge regions, and said distal ends of said plurality of ribbon members being positioned proximate each other in a constrained relationship, wherein a conical shaped base valve member is formed, and wherein fluid flow through said constrained distal ends of said plurality of ribbon members is restricted, said conical shaped base valve member being configured to expand during positive fluid flow through said conical shaped base valve member and contract during negative fluid flow through said conical shaped base valve member, said plurality of contiguous ribbon edge regions being configured to open during said expansion of said conical shaped base valve member, wherein said positive fluid flow is allowed to be transmitted through said plurality of contiguous ribbon edge regions, and close during said contraction of said conical shaped base valve member, wherein said negative fluid flow through said conical shaped base valve member is restricted; and a biodegradable structural ring configured to receive said distal ends of said ribbon members therein and maintain said distal ends of said ribbon members in said constrained relationship, said structural ring comprising an extracellular matrix composition comprising acellular extracellular matrix from a mammalian tissue source, said conical shaped base valve member and said structural ring being adapted to fully degrade and remodel in vivo, said conical shaped base valve member and said structural ring, when disposed proximate damaged cardiovascular tissue, being further adapted to induce remodeling of said damaged cardiovascular tissue and regeneration of new cardiovascular tissue and tissue structures with site-specific structural and functional properties.
Plastics material container with a mouth region, a main body adjoining this mouth region in a longitudinal direction of the plastics material container, this main body having a peripheral wall extending in a circumferential direction of the plastic container and a container base adjoining this main body, wherein this container base has a central region and a plurality of reinforcing ribs (64, 66) which, starting from this central region, extend in the direction of the circumferential wall, wherein a stepped portion extending at least partially in the circumferential region of the plastic container is provided in a circumferential region of the container base which extends around the longitudinal direction, characterized in that a vertical position of this stepped portion varies in the longitudinal direction.
A recording material comprising: a) a support in the form of a sheet-like structure comprising at least one colored surface; and, disposed thereon, b) a layer comprising polymeric particles having a core/shell structure, said particles having an outer first polymer shell having a calculated Tg of from 40 °C to 130 °C, said particles comprising, when dry, at least one void; and from 1% to 90%, by weight based on the weight of said polymer particles, opacity reducer having a melting point of from 45°C to 200°C, wherein said colored surface has sufficient color density to be visibly contrasting to the surface of the subsequent layer dispersed thereon; wherein said opacity reducer is an aromatic oxalic acid ester, aromatic ethylene glycol ether, 1,2-diphenyloxyethane, dibenzyl oxalate, dibenzyl terephthalate, benzyl-biphenyl, benzyl-2-naphthyl ether, diphenyl sulfone, m-terphenyl, p-benzyloxybenzyl benzoate, cyclohexane dimethanol benzoate, p-toluenesulfonamide, o-toluenesulfonamide, 2,6-diisopropyl naphthalene, 4,4-diisopropyl biphenyl, erucamide, stearic acid amide, palmitic acid amide, or ethylene-bis-stearic acid amide. a) a support in the form of a sheet-like structure comprising at least one colored surface; and, disposed thereon, b) a layer comprising polymeric particles having a core/shell structure, said particles having an outer first polymer shell having a calculated Tg of from 40 °C to 130 °C, said particles comprising, when dry, at least one void; and from 1% to 90%, by weight based on the weight of said polymer particles, opacity reducer having a melting point of from 45°C to 200°C, wherein said colored surface has sufficient color density to be visibly contrasting to the surface of the subsequent layer dispersed thereon; wherein said opacity reducer is an aromatic oxalic acid ester, aromatic ethylene glycol ether, 1,2-diphenyloxyethane, dibenzyl oxalate, dibenzyl terephthalate, benzyl-biphenyl, benzyl-2-naphthyl ether, diphenyl sulfone, m-terphenyl, p-benzyloxybenzyl benzoate, cyclohexane dimethanol benzoate, p-toluenesulfonamide, o-toluenesulfonamide, 2,6-diisopropyl naphthalene, 4,4-diisopropyl biphenyl, erucamide, stearic acid amide, palmitic acid amide, or ethylene-bis-stearic acid amide.
Method for operating a refrigeration and/or freezer device with at least one refrigeration unit that can be operated on at least two different power levels, wherein the duration of at least an operating time and/or at least a dwell time of the refrigeration unit is changed dependent upon at least one characteristic of the energy that the refrigeration unit is operated with, characterized in that the duration of an operating time until the refrigeration unit is switched from one power level to a higher or lower power level is reduced or extended dependent upon the characteristic of the energy.
A method, comprising: transmitting, by a wireless device, a data accumulation request to an access node of a wireless network, wherein the data accumulation request comprises at least one downlink accumulation rule for accumulating downlink data; receiving a message from the access node, wherein the message indicates that there is downlink data in the access node for the wireless device; and triggering a service period for receiving the downlink data from the access node upon determining, on the basis of the received message, that the downlink data satisfies the at least one downlink accumulation rule. transmitting, by a wireless device, a data accumulation request to an access node of a wireless network, wherein the data accumulation request comprises at least one downlink accumulation rule for accumulating downlink data; receiving a message from the access node, wherein the message indicates that there is downlink data in the access node for the wireless device; and triggering a service period for receiving the downlink data from the access node upon determining, on the basis of the received message, that the downlink data satisfies the at least one downlink accumulation rule.
A homo-multimer of genetically fused recombinant biologically active protein monomer units, connected via a suitable peptide linker moiety, wherein each protein monomer unit comprises the amino acid sequence of recombinant human granulocyte colony-stimulating factor (rhG-CSF) or essentially the same sequence of at least 95% identity, said linker moiety being represented by the amino acid sequence, selected from the group, consisting of SGLEA-(EAAAK) m -ALEA-(EAAAK) m -ALEGS, wherein m=2-8, preferably represented by SEQ ID No:5.
A microorganism detecting method for detecting a microbial colony cultivated in a medium, the method being characterized by a training step and an identifying step, wherein the training step includes: capturing a color image of a learning subject with or without a microbial colony within a medium region, setting at least a part of the medium region as a training subject region within the captured color image; obtaining, as learning data, color data of medium points within the training subject region in the captured color image of the learning subject without a microbial colony in the medium region; supplying the learning data to a classifier to obtain feature vectors of the color data; and separating, by the classifier, a set of points specified by the feature vectors to classify a class of medium, by setting a threshold at a position distant outward by a predetermined distance from the set of points specified by the feature vectors, and the identifying step includes: supplying, to the trained classifier, color data of each inspection point within an inspection subject region in a captured color image of an inspection subject to obtain a feature vector of the color data; determining, by the classifier, whether or not the inspection point specified by the feature vector belongs to the class of medium; and identifying a colony based on the inspection point that has been determined to not belong to the class of medium. capturing a color image of a learning subject with or without a microbial colony within a medium region, setting at least a part of the medium region as a training subject region within the captured color image; obtaining, as learning data, color data of medium points within the training subject region in the captured color image of the learning subject without a microbial colony in the medium region; supplying the learning data to a classifier to obtain feature vectors of the color data; and separating, by the classifier, a set of points specified by the feature vectors to classify a class of medium, by setting a threshold at a position distant outward by a predetermined distance from the set of points specified by the feature vectors, and supplying, to the trained classifier, color data of each inspection point within an inspection subject region in a captured color image of an inspection subject to obtain a feature vector of the color data; determining, by the classifier, whether or not the inspection point specified by the feature vector belongs to the class of medium; and identifying a colony based on the inspection point that has been determined to not belong to the class of medium.
Sealing arrangement comprising two components (2a, 2b) which can be moved in relation to one another as a result of mechanical or thermal action and are spaced apart opposite one another by a gap, wherein the mutually opposite walls of the components (2a, 2b) are each provided with a component groove (3a, 3b) in which a plate-like sealing element is arranged in order to seal the gap, wherein the component grooves (3a, 3b) have groove side walls (9a, 9b) which are each located opposite, and parallel, to one another and are spaced apart from one another by a groove width which is at most 1.1 times greater than an overall thickness of the sealing element, wherein the sealing element is directed along a main line and, as seen in a cross section essentially perpendicular to the main line, has a central region which is arranged between a first end and a second end and has a first surface which is toothed, wherein the direction of the transverse extent of the plate-like sealing element between the two ends (6a, 6b), which are accommodated in the component grooves (3a, 3b), corresponds to the direction of the gap spacing, wherein each sealing tooth extends parallel to the main line, and perpendicular to a possible leakage flow, and the overall thickness of the sealing element includes the tooth height, characterized in that all the sealing teeth have a more or less rectangular cross-sectional contour and the tooth height thereof is between 10% and 40% of the overall thickness of the sealing element, in that the spacing between two directly adjacent sealing teeth is 1.6 times the average tooth height of the two sealing teeth, and in that the average spacing between two directly adjacent sealing teeth of the sealing element is at least 5 times the difference between the groove width and the overall sealing-element thickness.
Frame of bumpers with a top wall extending in one plane, two supporting legs intended to support one bumper beam and extending both on the same side of the upper wall, the upper wall having two frangible surfaces arranged in each the extension of each of the supporting legs and surrounded by each of a frangible zone (43, 44), characterized by the ends of the supporting legs opposite the upper wall being connected by a connecting branch, of section in "L" arranged so that the section in "L" is intended to cover one edge of a bumper beam.
A two-dimensional code (1; 120; 130;...) having a rectangular region delineated by a single border (6, 106) made of a plurality of border lines (6a, 6b, 6c, 6d; 106a, 106b, 106c, 106d) delineated from a background provided by an object on or in which the code is present, the code comprising: a plurality of code blocks including a plurality of data code blocks and a plurality of error-correction code blocks, the data code blocks being blocks in which data are coded, the error-correction code blocks being for correcting an error in the data code blocks, the data code blocks and the error-correction code blocks being composed of a plurality of cells which are aggregated; a first specific pattern (2; 202; 289;...) configured to specify the positions of the cells; and a second specific pattern (3, 4; 133, 134; 143, 144;...) configured to distinguish the code blocks from the background, wherein the code blocks, the first specific pattern and the second specific pattern are arranged in the rectangular region, the first specific pattern is located at a specified corner of the rectangular region, the second specific pattern is located along one or more border lines (6a, 6b; 106a, 106b) of two first border lines (6a, 6b; 106a, 106b) along which the first specific pattern is located, the second specific pattern being adjacent to the first specific pattern, the first border lines being part of the border lines of the rectangular region,and characterized in that the error-correction code blocks are located along second border lines (6c, 6d; 106c, 106d) which are different from the one or more border lines of the two first border lines, the second border lines being part of the border lines of the rectangular region. a plurality of code blocks including a plurality of data code blocks and a plurality of error-correction code blocks, the data code blocks being blocks in which data are coded, the error-correction code blocks being for correcting an error in the data code blocks, the data code blocks and the error-correction code blocks being composed of a plurality of cells which are aggregated; a first specific pattern (2; 202; 289;...) configured to specify the positions of the cells; and a second specific pattern (3, 4; 133, 134; 143, 144;...) configured to distinguish the code blocks from the background, wherein the code blocks, the first specific pattern and the second specific pattern are arranged in the rectangular region, the first specific pattern is located at a specified corner of the rectangular region, the second specific pattern is located along one or more border lines (6a, 6b; 106a, 106b) of two first border lines (6a, 6b; 106a, 106b) along which the first specific pattern is located, the second specific pattern being adjacent to the first specific pattern, the first border lines being part of the border lines of the rectangular region,and characterized in that the error-correction code blocks are located along second border lines (6c, 6d; 106c, 106d) which are different from the one or more border lines of the two first border lines, the second border lines being part of the border lines of the rectangular region.