A method of manufacturing a silicone hydrogel contact lens body, comprising: providing a first mold member and a second mold member, the first mold member comprising a concave molding surface configured to mold an anterior surface of a contact lens and the second mold member comprising a convex molding surface configured to mold a posterior surface of a contact lens, the first mold member and the second mold member being configured to form a lens-shaped cavity therebetween when combined as a mold assembly, the molding surface of at least one of the first mold member and the second mold member comprising a thermoplastic polymer, the molding surface having a percent polarity from 3% to 20% and a surface energy from 25 mN/m to 40mN/m; placing a polymerizable composition comprising a) at least one silicon-containing monomer and b) at least one hydrophilic monomer in the first mold member, the polymerizable composition having a surface tension from 20 mN/m to 25 mN/m, and a surface energy differential of the surface tension of the polymerizable composition less the surface energy of the molding surface is less than or equal to zero; assembling the mold assembly by placing the second mold member in contact with the first mold member so as to form a lens-shaped cavity therebetween with the polymerizable composition contained in the lens-shaped cavity of the mold assembly; and curing the polymerizable composition in the mold assembly to form a cast-molded polymerized reaction product in the lens-shaped cavity of the mold assembly, the polymerized reaction product comprising a silicone hydrogel contact lens body. providing a first mold member and a second mold member, the first mold member comprising a concave molding surface configured to mold an anterior surface of a contact lens and the second mold member comprising a convex molding surface configured to mold a posterior surface of a contact lens, the first mold member and the second mold member being configured to form a lens-shaped cavity therebetween when combined as a mold assembly, the molding surface of at least one of the first mold member and the second mold member comprising a thermoplastic polymer, the molding surface having a percent polarity from 3% to 20% and a surface energy from 25 mN/m to 40mN/m; placing a polymerizable composition comprising a) at least one silicon-containing monomer and b) at least one hydrophilic monomer in the first mold member, the polymerizable composition having a surface tension from 20 mN/m to 25 mN/m, and a surface energy differential of the surface tension of the polymerizable composition less the surface energy of the molding surface is less than or equal to zero; assembling the mold assembly by placing the second mold member in contact with the first mold member so as to form a lens-shaped cavity therebetween with the polymerizable composition contained in the lens-shaped cavity of the mold assembly; and curing the polymerizable composition in the mold assembly to form a cast-molded polymerized reaction product in the lens-shaped cavity of the mold assembly, the polymerized reaction product comprising a silicone hydrogel contact lens body. placing a polymerizable composition comprising a) at least one silicon-containing monomer and b) at least one hydrophilic monomer in the first mold member, the polymerizable composition having a surface tension from 20 mN/m to 25 mN/m, and a surface energy differential of the surface tension of the polymerizable composition less the surface energy of the molding surface is less than or equal to zero; assembling the mold assembly by placing the second mold member in contact with the first mold member so as to form a lens-shaped cavity therebetween with the polymerizable composition contained in the lens-shaped cavity of the mold assembly; and curing the polymerizable composition in the mold assembly to form a cast-molded polymerized reaction product in the lens-shaped cavity of the mold assembly, the polymerized reaction product comprising a silicone hydrogel contact lens body.