A medical device system for providing CRT therapy to a patient, comprising: a pulse generator; two or more left ventricle electrodes (LV1, LV2, LV3, LV4) operatively coupled to the pulse generator; and a controller configured to: determine an electrical delay associated with each of the two or more left ventricle electrodes (LV1, LV2, LV3, LV4), wherein each of the two or more left ventricle electrodes (LV1, LV2, LV3, LV4) is included in a different stimulation vector which includes an anode and a cathode, and wherein the electrical delay is a measure of time delay between delivery of electrical stimulation to the cathode of a stimulation vector and detecting the electrical stimulation at the anode of the stimulation vector; compare the electrical delay associated with each of the two or more left ventricle electrodes (LV1, LV2, LV3, LV4) to an electrical delay threshold; if the electrical delay associated with one or fewer left ventricle electrodes (LV1, LV2, LV3, LV4) is greater than the electrical delay threshold, select a single left ventricle electrode (LV1, LV2, LV3, LV4) for use during subsequent CRT therapy; and if the electrical delay associated with more than one left ventricle electrode (LV1, LV2, LV3, LV4) is greater than the electrical delay threshold, select two or more of the left ventricle electrodes (LV1, LV2, LV3, LV4) for use during subsequent CRT therapy. a pulse generator; two or more left ventricle electrodes (LV1, LV2, LV3, LV4) operatively coupled to the pulse generator; and a controller configured to: determine an electrical delay associated with each of the two or more left ventricle electrodes (LV1, LV2, LV3, LV4), wherein each of the two or more left ventricle electrodes (LV1, LV2, LV3, LV4) is included in a different stimulation vector which includes an anode and a cathode, and wherein the electrical delay is a measure of time delay between delivery of electrical stimulation to the cathode of a stimulation vector and detecting the electrical stimulation at the anode of the stimulation vector; compare the electrical delay associated with each of the two or more left ventricle electrodes (LV1, LV2, LV3, LV4) to an electrical delay threshold; if the electrical delay associated with one or fewer left ventricle electrodes (LV1, LV2, LV3, LV4) is greater than the electrical delay threshold, select a single left ventricle electrode (LV1, LV2, LV3, LV4) for use during subsequent CRT therapy; and if the electrical delay associated with more than one left ventricle electrode (LV1, LV2, LV3, LV4) is greater than the electrical delay threshold, select two or more of the left ventricle electrodes (LV1, LV2, LV3, LV4) for use during subsequent CRT therapy. determine an electrical delay associated with each of the two or more left ventricle electrodes (LV1, LV2, LV3, LV4), wherein each of the two or more left ventricle electrodes (LV1, LV2, LV3, LV4) is included in a different stimulation vector which includes an anode and a cathode, and wherein the electrical delay is a measure of time delay between delivery of electrical stimulation to the cathode of a stimulation vector and detecting the electrical stimulation at the anode of the stimulation vector; compare the electrical delay associated with each of the two or more left ventricle electrodes (LV1, LV2, LV3, LV4) to an electrical delay threshold; if the electrical delay associated with one or fewer left ventricle electrodes (LV1, LV2, LV3, LV4) is greater than the electrical delay threshold, select a single left ventricle electrode (LV1, LV2, LV3, LV4) for use during subsequent CRT therapy; and if the electrical delay associated with more than one left ventricle electrode (LV1, LV2, LV3, LV4) is greater than the electrical delay threshold, select two or more of the left ventricle electrodes (LV1, LV2, LV3, LV4) for use during subsequent CRT therapy.