mhurhangee/ep-ind-claims huggingface dataset:
A mouse whose germline genome comprises an endogenous immunoglobulin λ light chain locus comprising: (a) one or more human Vλ gene segments, (b) one or more human Jλ gene segments, (c) one or more human Cλ gene segments, and (d) a mouse Cλ gene segment, wherein (a) and (b) are capable of rearranging to form rearranged human λ variable region genes that are expressed in conjunction with the constant region gene segment(s) of (c) as λ light chains of antigen binding proteins, and wherein (a) and (b) are also capable of rearranging to form rearranged human λ variable region genes that are expressed in conjunction with the mouse Cλ gene segment of (d) as λ light chains of antigen binding proteins, and wherein the endogenous immunoglobulin λ light chain locus further comprises: one or more mouse immunoglobulin λ light chain enhancers (Eλ), and one or more human immunoglobulin λ light chain enhancers (Eλ). (a) one or more human Vλ gene segments, (b) one or more human Jλ gene segments, (c) one or more human Cλ gene segments, and (d) a mouse Cλ gene segment,
A device for extracorporeal blood treatment comprising: at least one exchanger exhibiting at least a first inlet for blood to be treated, a first fluid outlet and a second fluid outlet, the exchanger being a plasma filter, wherein the plasma filter has a cut-off point between one million and five million Daltons, an inlet line for blood to be treated, connected to the first inlet of the exchanger, a blood outlet line connected to the first outlet of the exchanger, at least one treatment unit exhibiting at least a first fluid inlet and at least a first fluid outlet, wherein the treatment unit comprises an adsorption cartridge or a reactor capable of fixing at least one given substance, a first tube connecting the second outlet of the exchanger to the first inlet of the treatment unit, a channel connecting the first outlet of the treatment unit to a branching point of the inlet line, so as to place the first outlet of the treatment unit in fluid communication with the inlet line, liquid flow rate regulating means on the second channel, characterized in that the device comprises liquid flow rate regulating means on the first tube. at least one exchanger exhibiting at least a first inlet for blood to be treated, a first fluid outlet and a second fluid outlet, the exchanger being a plasma filter, wherein the plasma filter has a cut-off point between one million and five million Daltons, an inlet line for blood to be treated, connected to the first inlet of the exchanger, a blood outlet line connected to the first outlet of the exchanger, at least one treatment unit exhibiting at least a first fluid inlet and at least a first fluid outlet, wherein the treatment unit comprises an adsorption cartridge or a reactor capable of fixing at least one given substance, a first tube connecting the second outlet of the exchanger to the first inlet of the treatment unit, a channel connecting the first outlet of the treatment unit to a branching point of the inlet line, so as to place the first outlet of the treatment unit in fluid communication with the inlet line, liquid flow rate regulating means on the second channel, characterized in that the device comprises liquid flow rate regulating means on the first tube.
A filter housing for use in filtration of fuel, hydraulic fluids or lubricating fluids comprising: (a) a surrounding wall defining an interior volume; the surrounding wall having an interior surface in communication with the interior volume and an opposite exterior surface; the housing having first and second opposite ends (29, 32), and an open mouth in communication with the interior volume at the first end; (i) a longitudinal axis extending through the first and second ends (29, 32) of the housing; and (b) a threaded section for connecting with a filter head with a threaded section first end and an opposite threaded section second end; the threaded section first end being above the threaded section second end when the housing is oriented with longitudinal axis extending vertically and the housing first end being above the housing second end; (i) the threaded section being angled at an angle relative to a line parallel to the longitudinal axis, as the threaded section extends from the threaded section first end next to the mouth toward the threaded section second end spaced from the mouth; (ii) the angle being at least 1 degree; characterized in that the filter housing further includes a recess located axially between the threaded section and the mouth, the recess holding a seal member. (a) a surrounding wall defining an interior volume; the surrounding wall having an interior surface in communication with the interior volume and an opposite exterior surface; the housing having first and second opposite ends (29, 32), and an open mouth in communication with the interior volume at the first end; (i) a longitudinal axis extending through the first and second ends (29, 32) of the housing; and (i) a longitudinal axis extending through the first and second ends (29, 32) of the housing; and (b) a threaded section for connecting with a filter head with a threaded section first end and an opposite threaded section second end; the threaded section first end being above the threaded section second end when the housing is oriented with longitudinal axis extending vertically and the housing first end being above the housing second end; (i) the threaded section being angled at an angle relative to a line parallel to the longitudinal axis, as the threaded section extends from the threaded section first end next to the mouth toward the threaded section second end spaced from the mouth; (ii) the angle being at least 1 degree; (i) the threaded section being angled at an angle relative to a line parallel to the longitudinal axis, as the threaded section extends from the threaded section first end next to the mouth toward the threaded section second end spaced from the mouth; (ii) the angle being at least 1 degree;
A dry cleaning apparatus for cleaning articles using fluids comprising, - a compressor unit for processing fluid, - a storage unit for storage of the fluid, - a cooling unit arranged between the compressor unit and the storage unit for cooling of the fluid, characterised by a regulator associated with the compressor unit, the regulator is arranged before the storage unit for increasing pressure of the fluid where the cooling unit is arranged, between the compressor unit and the regulator. - a compressor unit for processing fluid, - a storage unit for storage of the fluid, - a cooling unit arranged between the compressor unit and the storage unit for cooling of the fluid,
A resonator assembly comprising: a first ceramic resonator article having determined radio frequency resonance characteristics; a second ceramic resonator article having determined radio frequency resonance characteristics; characterized by the resonator assembly further comprising a replaceable coupling sheet attached between the first ceramic resonator article and the second ceramic resonator article, wherein the replaceable coupling sheet is made of electrically conductive material and comprises a pattern in the form of at least one through hole for tuning properties of the resonator assembly. a first ceramic resonator article having determined radio frequency resonance characteristics; a second ceramic resonator article having determined radio frequency resonance characteristics; characterized by the resonator assembly further comprising a replaceable coupling sheet attached between the first ceramic resonator article and the second ceramic resonator article, wherein the replaceable coupling sheet is made of electrically conductive material and comprises a pattern in the form of at least one through hole for tuning properties of the resonator assembly.
A settable composition for cementing a subterranean formation comprising: wollastonite; pumice; a calcium-ion source comprising lime; and water; wherein the wollastonite is present in an amount in a range of from 25% to 75% by combined weight of the wollastonite and pumice; wherein the pumice is present in an amount in a range of from 25% to 75% by combined weight of the wollastonite and pumice; and wherein the settable composition is free of Portland cement. wollastonite; pumice; a calcium-ion source comprising lime; and water; wherein the wollastonite is present in an amount in a range of from 25% to 75% by combined weight of the wollastonite and pumice; wherein the pumice is present in an amount in a range of from 25% to 75% by combined weight of the wollastonite and pumice; and wherein the settable composition is free of Portland cement.
A compound comprising a modified compstatin peptide (ICVVQDWGHHRCT (cyclic C2-C12; SEQ ID NO: 1), wherein the modification comprises an added or substituted N-terminal component that improves the peptide's C3, C3b or C3c binding affinity, the peptide's solubility in aqueous liquids, and/or the peptide's plasma stability and/or plasma residence time, as compared with an unmodified compstatin peptide under equivalent conditions, wherein the added component is D-Tyr, D-Phe, Tyr(Me), D-Trp, D-Cha, Phe, N-methyl Gly (Sar), Arg, mPhe, mVal, or Tyr, and wherein the substituted N-terminal component comprises Ile at position 1 being replaced with Ac-Trp; wherein the compound further comprises one or more of: replacement of His at position 9 with Ala; replacement of Val at position 4 with Trp or an analog of Trp, wherein the analog of Trp optionally is 1-methyl Trp or 1-formyl Trp; replacement of Trp at position 7 with an analog of Trp, optionally wherein the analog of Trp is a halogenated Trp; modification of Gly at position 8 to constrain the backbone conformation at that location, optionally wherein the backbone is constrained by replacing the Gly at position 8 with N-alpha-methyl Gly; replacement of the Thr at position 13 with Ile, Leu, Nle, N-methyl Thr or N-methyl Ile; and replacement of the disulfide bond between C2 and C12 with a thioether bond to form a cystathionine or a lantithionine.
An implantable medical device (410, 510, 610) comprising: a substrate (415, 515, 615); the substrate comprising a surgical mesh which includes a plurality of spiked naps (417, 517, 617); and at least one polymeric film layer (420, 520, 620a, 620b); characterised in that the film layer consists of glycerol and carboxymethylcellulose, wherein the glycerol represents more than 50 weight percent of the polymeric film layer and the carboxymethylcellulose represents less than 50 weight percent of the polymeric film layer, wherein said polymeric film is attached to the substrate and further comprises at least one therapeutic agent. a substrate (415, 515, 615); the substrate comprising a surgical mesh which includes a plurality of spiked naps (417, 517, 617); and at least one polymeric film layer (420, 520, 620a, 620b); characterised in that the film layer consists of glycerol and carboxymethylcellulose, wherein the glycerol represents more than 50 weight percent of the polymeric film layer and the carboxymethylcellulose represents less than 50 weight percent of the polymeric film layer, wherein said polymeric film is attached to the substrate and further comprises at least one therapeutic agent.
A magnet for an anti-ice system for a fan assembly of a gas turbine engine, comprising: a core comprising a first material having magnetic qualities; and at least one coil wound about a perimeter of the core, the at least one coil comprising a second material, wherein the magnet is an electromagnet configured to emit a magnetic field in response to an electric current applied to at least one coil; characterised in that: the first material has a first epoxy composition and the second material has a second epoxy composition, wherein the second epoxy composition is a conductive epoxy composition, wherein the first epoxy composition and the second epoxy composition each comprise a bisphenolic resin composition comprising bisphenol AF and at least one of a filler or a conductivity modifier. a core comprising a first material having magnetic qualities; and at least one coil wound about a perimeter of the core, the at least one coil comprising a second material, wherein the magnet is an electromagnet configured to emit a magnetic field in response to an electric current applied to at least one coil; characterised in that: the first material has a first epoxy composition and the second material has a second epoxy composition, wherein the second epoxy composition is a conductive epoxy composition, wherein the first epoxy composition and the second epoxy composition each comprise a bisphenolic resin composition comprising bisphenol AF and at least one of a filler or a conductivity modifier.
A dental x-ray system comprising: - a first substantially vertical column; - a second substantially vertical column supporting a dental x-ray device, the second column being movable with respect to the first column; - a motor connected to the second column, the motor having a threaded shaft extending toward the first column; - a threaded sleeve in threaded engagement with the shaft, the threaded sleeve extending away from the second column, wherein the end of the sleeve opposite the shaft is disposed in a boss adjacent a base of the first column; and wherein the motor controllably moving the second column with respect to the first column by rotating the shaft with respect to the sleeve. - a first substantially vertical column; - a second substantially vertical column supporting a dental x-ray device, the second column being movable with respect to the first column; - a motor connected to the second column, the motor having a threaded shaft extending toward the first column; - a threaded sleeve in threaded engagement with the shaft, the threaded sleeve extending away from the second column, wherein the end of the sleeve opposite the shaft is disposed in a boss adjacent a base of the first column; and
A heart valve prosthesis for replacing a diseased native valve in a heart of a patient, the valve prosthesis having an axis and comprising: a compressible and expandable frame structure; a valve segment disposed within the frame structure, the valve segment comprising a biocompatible one-way valve; and an expandable anchor connected to an outer periphery of the frame structure, wherein the anchor comprises a wire formed in a helical shape around the frame structure, the wire having a free end and wherein the other end of the helically shaped wire is attached to a top end of the frame structure; wherein the valve prosthesis is configured such that, when the valve prosthesis comes out from a delivery catheter, the anchor expands to a pre-formed deployed state and wraps around the frame structure, which remains in its collapsed state; and wherein the free end of the helically shaped wire is configured to guide the helically shaped wire through a commissure of a native valve of a patient when the helically shaped wire is rotated. a compressible and expandable frame structure; a valve segment disposed within the frame structure, the valve segment comprising a biocompatible one-way valve; and an expandable anchor connected to an outer periphery of the frame structure, wherein the anchor comprises a wire formed in a helical shape around the frame structure, the wire having a free end and wherein the other end of the helically shaped wire is attached to a top end of the frame structure; wherein the valve prosthesis is configured such that, when the valve prosthesis comes out from a delivery catheter, the anchor expands to a pre-formed deployed state and wraps around the frame structure, which remains in its collapsed state; and wherein the free end of the helically shaped wire is configured to guide the helically shaped wire through a commissure of a native valve of a patient when the helically shaped wire is rotated.
A control system for controlling an electric power steering system, the control system comprising: a first module configured to compute an on-center torque adjustment compensation based on a sensed handwheel torque, the on-center torque adjustment compensation configured to compensate for inertia of a steering actuator motor using a frequency-based methodology; and a second module configured to generate a command signal to control the steering actuator motor of the electric power steering system based on the on-center torque adjustment compensation, characterized in that the on-center torque adjustment compensation further comprises a gain function and a base transfer function applied to the sensed handwheel torque, wherein the base transfer function is configured to implement a multi-order transfer function for a plurality of corner frequencies and is characterized by an equation: s 2 P 1 P 2 s + P 1 s + P 2, where s is a complex frequency, and P 1 and P 2 define the corner frequencies. a first module configured to compute an on-center torque adjustment compensation based on a sensed handwheel torque, the on-center torque adjustment compensation configured to compensate for inertia of a steering actuator motor using a frequency-based methodology; and a second module configured to generate a command signal to control the steering actuator motor of the electric power steering system based on the on-center torque adjustment compensation, characterized in that the on-center torque adjustment compensation further comprises a gain function and a base transfer function applied to the sensed handwheel torque, wherein the base transfer function is configured to implement a multi-order transfer function for a plurality of corner frequencies and is characterized by an equation: s 2 P 1 P 2 s + P 1 s + P 2, where s is a complex frequency, and P 1 and P 2 define the corner frequencies.
A preform made of plastic material for producing a PET bottle having a volume smaller than 1 L and weighing less than 16 g by means of a stretching-blowing operation, said preform defining a longitudinal axis and provided at a first end thereof with a cylindrical neck and defining the following parts in sequence: - a threaded end portion for screwing a cap, - a neck ring, under said threaded end portion, - a first cylindrical connection segment having a first predetermined outer diameter and a wall having a first thickness (t 1) substantially equal to the thickness of the bottle in the same zone, - a preform body, intended to be heated before the blowing operation, defining in turn the following parts: - a second connection segment with outer wall tapered by a first angle (α) with respect to the longitudinal axis and with inner wall tapered by a second angle (β) with respect to the longitudinal axis, and having a predetermined length (H 3) on the longitudinal axis, - a cylindrical segment having a second outer diameter smaller than said first outer diameter and a second thickness (t 2) greater than the first thickness (t 1), - a bottom which closes a second end of the preform, wherein the first angle (α) is from 6° to 10°, characterized in that - the second thickness (t 2) is from 1,4 to 1,7 mm, - the second angle (β) is from 9° to 13°, - the length (H 3) is from 14 to 18,5 mm. - a threaded end portion for screwing a cap, - a neck ring, under said threaded end portion, - a first cylindrical connection segment having a first predetermined outer diameter and a wall having a first thickness (t 1) substantially equal to the thickness of the bottle in the same zone, - a preform body, intended to be heated before the blowing operation, defining in turn the following parts: - a second connection segment with outer wall tapered by a first angle (α) with respect to the longitudinal axis and with inner wall tapered by a second angle (β) with respect to the longitudinal axis, and having a predetermined length (H 3) on the longitudinal axis, - a cylindrical segment having a second outer diameter smaller than said first outer diameter and a second thickness (t 2) greater than the first thickness (t 1), - a bottom which closes a second end of the preform, wherein the first angle (α) is from 6° to 10°, characterized in that - the second thickness (t 2) is from 1,4 to 1,7 mm, - the second angle (β) is from 9° to 13°, - the length (H 3) is from 14 to 18,5 mm.
A fairing with a bypass duct for diverting compressed air in part from a high pressure compressor and a combustor toward a turbine outlet of a turbofan engine having an axis, the fairing with the bypass duct comprising: an outer casing and an inner casing defining the bypass duct around the high pressure compressor and the combustor, when installed, the bypass duct having an inlet just behind a low pressure compressor of the turbofan engine and an outlet opened at the turbine outlet, when installed; a fore section elongated aftward from the inner casing at the inlet of the bypass duct and running along an internal periphery of the outer casing; and an aft section elongated aftward in succession to the fore section and curved in a direction getting away from the internal periphery so as to increase an area (A1, A2) of a flow path toward the rear, the whole of the aft section being curved, wherein the aft section terminates at an aft end being parallel with the axis, and wherein a ratio of the area of the flow path at the aft end to the area of the flow path at the inlet is from 1.5 to 2.0. an outer casing and an inner casing defining the bypass duct around the high pressure compressor and the combustor, when installed, the bypass duct having an inlet just behind a low pressure compressor of the turbofan engine and an outlet opened at the turbine outlet, when installed; a fore section elongated aftward from the inner casing at the inlet of the bypass duct and running along an internal periphery of the outer casing; and an aft section elongated aftward in succession to the fore section and curved in a direction getting away from the internal periphery so as to increase an area (A1, A2) of a flow path toward the rear, the whole of the aft section being curved, wherein the aft section terminates at an aft end being parallel with the axis, and wherein a ratio of the area of the flow path at the aft end to the area of the flow path at the inlet is from 1.5 to 2.0.
A method for transmitting and receiving signals at a user equipment, UE, in a time division duplex, TDD, communication system, the method comprising: configuring a first uplink/downlink configuration among a plurality of uplink/downlink configurations by a higher layer; and configuring to detect a second uplink/downlink configuration among the plurality of uplink/downlink configurations in a physical downlink control channel, PDCCH; and transmitting and receiving the signals based on the first uplink/downlink configuration or the second uplink/downlink configuration, wherein, if a transmission of a periodic Sounding Reference Signal, SRS, is configured by the higher layer and if the second uplink/downlink configuration is not detected, the UE does not transmit the periodic SRS in a subframe indicated as a downlink subframe by the first uplink/downlink configuration. configuring a first uplink/downlink configuration among a plurality of uplink/downlink configurations by a higher layer; and configuring to detect a second uplink/downlink configuration among the plurality of uplink/downlink configurations in a physical downlink control channel, PDCCH; and transmitting and receiving the signals based on the first uplink/downlink configuration or the second uplink/downlink configuration, wherein, if a transmission of a periodic Sounding Reference Signal, SRS, is configured by the higher layer and if the second uplink/downlink configuration is not detected, the UE does not transmit the periodic SRS in a subframe indicated as a downlink subframe by the first uplink/downlink configuration.