mhurhangee/ep-ind-claims huggingface dataset:
A method for producing empty inactive or full active parvovirus particles, said method comprising: (a) providing the producer cell line NB-324K; (b) growing the cell line under suitable conditions and infecting the cells at a cell density from 2.0 to 5.0 x 10 4 cells/cm 2 with the parvovirus at a MOI of 0,5 to 2 x 10 -2 PFU/cells; (c) harvesting the cells 2 to 6 days post-infection and obtaining a cell pellet by centrifugation; (d) subjecting the resuspended cell pellet to a mechanical, physical or chemical cell lysis method for obtaining a parvovirus containing cell lysate; (e) sonicating the cell lysate and subjecting it to DNAse treatment; (f) clarifying the DNAse-treated parvovirus harvest by filtration; and purifying the parvovirus by two successive density gradient ultracentrifugations, wherein the first gradient is a Iodixanol/PBS step gradient and the second gradient is a Iodixanol/Ringer step gradient or a Iodixanol/Ringer continuous gradient for obtaining full active parvovirus particles in one fraction and empty parvovirus particles in another fraction. (a) providing the producer cell line NB-324K; (b) growing the cell line under suitable conditions and infecting the cells at a cell density from 2.0 to 5.0 x 10 4 cells/cm 2 with the parvovirus at a MOI of 0,5 to 2 x 10 -2 PFU/cells; (c) harvesting the cells 2 to 6 days post-infection and obtaining a cell pellet by centrifugation; (d) subjecting the resuspended cell pellet to a mechanical, physical or chemical cell lysis method for obtaining a parvovirus containing cell lysate; (e) sonicating the cell lysate and subjecting it to DNAse treatment; (f) clarifying the DNAse-treated parvovirus harvest by filtration; and purifying the parvovirus by two successive density gradient ultracentrifugations, wherein the first gradient is a Iodixanol/PBS step gradient and the second gradient is a Iodixanol/Ringer step gradient or a Iodixanol/Ringer continuous gradient for obtaining full active parvovirus particles in one fraction and empty parvovirus particles in another fraction.
An NMR measurement apparatus comprising: an acquisition unit (28, 34) arranged to acquire, from a nucleus of interest in a solvent included in a sample solution, an NMR spectrum including a characteristic portion intrinsic to the nucleus of interest; an analyzer arranged to analyze the characteristic portion, to thereby identify splitting information for a particular nucleus-of-interest signal included in the characteristic portion; and an identifier arranged to identify the solvent based on the splitting information, characterized in that the analyzer is arranged to identify a number of splits and a splitting interval as the splitting information, and the identifier is arranged to identify the solvent based on the number of splits and the splitting interval. an acquisition unit (28, 34) arranged to acquire, from a nucleus of interest in a solvent included in a sample solution, an NMR spectrum including a characteristic portion intrinsic to the nucleus of interest; an analyzer arranged to analyze the characteristic portion, to thereby identify splitting information for a particular nucleus-of-interest signal included in the characteristic portion; and an identifier arranged to identify the solvent based on the splitting information, characterized in that the analyzer is arranged to identify a number of splits and a splitting interval as the splitting information, and the identifier is arranged to identify the solvent based on the number of splits and the splitting interval.
A system for providing audio-derived information to a vehicle operator or vehicle control system of a vehicle, the vehicle having a vehicle data bus, the system comprising: (a) a plurality of microphones configured to be incorporated into the vehicle for generating an analog signal in response to sound waves external to the vehicle; (b) a plurality of analysis modules, wherein each microphone is associated with an analysis module which is integrated with the microphone and which is adapted for converting the analog signal to a digital signal, wherein each analysis module comprises a computer processor configured to identify or detect a target sound, and the digital signal comprises confirmation of identification or detection of the target sound, wherein each analysis module is configured to communicate the digital signal to the vehicle data bus for communicating or transferring the digital signal to the vehicle operator or vehicle control system. (a) a plurality of microphones configured to be incorporated into the vehicle for generating an analog signal in response to sound waves external to the vehicle; (b) a plurality of analysis modules, wherein each microphone is associated with an analysis module which is integrated with the microphone and which is adapted for converting the analog signal to a digital signal, wherein each analysis module comprises a computer processor configured to identify or detect a target sound, and the digital signal comprises confirmation of identification or detection of the target sound, wherein each analysis module is configured to communicate the digital signal to the vehicle data bus for communicating or transferring the digital signal to the vehicle operator or vehicle control system.
A process for synthesizing liraglutide with a low racemate impurity comprising: synthesizing to obtain a propeptide, and then coupling a 2~5 amino acid residue-containing peptide with Thr-Phe to the propeptide by using solid-phase synthesis, further performing a solid-phase synthesis to obtain a liraglutide resin, cleaving the liraglutide resin after side chain modification, or directly cleaving the liraglutide resin, purifying, and lyophilizing to give liraglutide, wherein the propeptide is Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(N-ε-(N-α-Palmitoyl-L-γ-glutamyl))-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly, wherein the 2~5 amino acid residue-containing peptide with Thr-Phe is Thr-Phe-Thr. synthesizing to obtain a propeptide, and then coupling a 2~5 amino acid residue-containing peptide with Thr-Phe to the propeptide by using solid-phase synthesis, further performing a solid-phase synthesis to obtain a liraglutide resin, cleaving the liraglutide resin after side chain modification, or directly cleaving the liraglutide resin, purifying, and lyophilizing to give liraglutide, wherein the propeptide is Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(N-ε-(N-α-Palmitoyl-L-γ-glutamyl))-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly, wherein the 2~5 amino acid residue-containing peptide with Thr-Phe is Thr-Phe-Thr.
A fixed focal length imaging optical system consisting of, in order from an object side toward an image side: a first lens group having positive power; a second lens group having positive power; and a third lens group having negative power, wherein the second lens group includes a single lens element having positive power, and upon focusing, the second lens group moves along an optical axis, and the first lens group and the third lens group do not move wherein the first lens group consists of, in order from the object side toward the image side, - a first A lens group (G1A) having negative power, the first A lens group (G1A) consisting of, in order from the object side toward the image side, a first lens element having positive power, and a second lens element having negative power, - aperture diaphragm, and - a first B lens group (G1B) having positive power, wherein the second lens group consists of a single lens element having positive power, and a condition shown below is satisfied, 1.70 < Nd2G < 1.85 where Nd2G is a refractive index of the second lens group at a d-line. a first lens group having positive power; a second lens group having positive power; and a third lens group having negative power, wherein the second lens group includes a single lens element having positive power, and upon focusing, the second lens group moves along an optical axis, and the first lens group and the third lens group do not move wherein the first lens group consists of, in order from the object side toward the image side, - a first A lens group (G1A) having negative power, the first A lens group (G1A) consisting of, in order from the object side toward the image side, a first lens element having positive power, and a second lens element having negative power, - aperture diaphragm, and - a first B lens group (G1B) having positive power, - a first A lens group (G1A) having negative power, the first A lens group (G1A) consisting of, in order from the object side toward the image side, a first lens element having positive power, and a second lens element having negative power, - aperture diaphragm, and - a first B lens group (G1B) having positive power, wherein the second lens group consists of a single lens element having positive power, and a condition shown below is satisfied, 1.70 < Nd2G < 1.85 where Nd2G is a refractive index of the second lens group at a d-line.
A compound of formula a stereo-isomeric form, a pharmaceutically acceptable salt, solvate or polymorph thereof, wherein X is N and Y is N; or X is C substituted by -F and Y is C substituted by -F, -CI, -CH 3, or -CN; Z is N, Q is selected from -C-CH 3, -C-COOH or -C-CF 3, and M is CF wherein R 1 is independently selected from hydrogen, halogen, cyano, oxo, alkyl, hydroxyl, amino; or Z is N, Q is N and M is CH; or Z is C, Q is N and M is CH; and R is C 3-8 cycloalkyl substituted by carboxylic acid, or -NH-C -C 3-6 heterocycle optionally substituted by C 1-6 alkyl or -COOH. X is N and Y is N; or X is C substituted by -F and Y is C substituted by -F, -CI, -CH 3, or -CN; Z is N, Q is selected from -C-CH 3, -C-COOH or -C-CF 3, and M is CF wherein R 1 is independently selected from hydrogen, halogen, cyano, oxo, alkyl, hydroxyl, amino; or Z is N, Q is N and M is CH; or Z is C, Q is N and M is CH; and R is C 3-8 cycloalkyl substituted by carboxylic acid, or -NH-C -C 3-6 heterocycle optionally substituted by C 1-6 alkyl or -COOH.
A camera module (100, 200, 300, 400, 500, 600, 1000, 1200) of a vehicle, comprising: a signal lamp comprising at least a first light source and being adapted to radiate light having a first color and a second color, the first color being different from the second color; and a camera module housing (110, 210, 310, 410, 510, 610, 1010, 1210) characterized in that a first light passage and a second light passage (120, 220, 320, 420, 520, 620, 1020, 1220) are arranged within the camera module housing (110, 210, 310, 410, 510, 610, 1010, 1210) and on the rear surface as seen from the driving direction of the camera module housing (110, 210, 310, 410, 510, 610, 1010, 1210), when the camera module housing (110, 210, 310, 410, 510, 610, 1010, 1210) is mounted on the vehicle, and being adapted to allow for light passing through from the first light source, wherein the first and second passages (120, 220, 320, 420, 520, 620, 1020, 1220) are to be arranged around a lens (130, 230, 330, 430, 530, 630, 1030, 1230) of a camera, wherein the first light source is a light emitting diode that is arranged at a rear portion of the camera module housing (110, 210, 310, 410, 510, 610, 1010, 1210), and the camera module further comprises a plurality of light guides connecting the LED to the first passage and the second passage (120, 220, 320, 420, 520, 620, 1020, 1220). a signal lamp comprising at least a first light source and being adapted to radiate light having a first color and a second color, the first color being different from the second color; and a camera module housing (110, 210, 310, 410, 510, 610, 1010, 1210) a first light passage and a second light passage (120, 220, 320, 420, 520, 620, 1020, 1220) are arranged within the camera module housing (110, 210, 310, 410, 510, 610, 1010, 1210) and on the rear surface as seen from the driving direction of the camera module housing (110, 210, 310, 410, 510, 610, 1010, 1210), when the camera module housing (110, 210, 310, 410, 510, 610, 1010, 1210) is mounted on the vehicle, and being adapted to allow for light passing through from the first light source, wherein the first and second passages (120, 220, 320, 420, 520, 620, 1020, 1220) are to be arranged around a lens (130, 230, 330, 430, 530, 630, 1030, 1230) of a camera, wherein the first light source is a light emitting diode that is arranged at a rear portion of the camera module housing (110, 210, 310, 410, 510, 610, 1010, 1210), and the camera module further comprises a plurality of light guides connecting the LED to the first passage and the second passage (120, 220, 320, 420, 520, 620, 1020, 1220).
An automatic valve and a source of a fire suppression agent, the automatic valve comprising a valve body, a piston and a first valve opening, wherein the body comprises a first part for receiving the piston therein and a second part, the second part comprising a connector for connecting the body to an air source providing pneumatic pressure, wherein the body is configured to receive the piston axially therein, wherein the piston is movable within the body between a first axial position in which the piston is configured to seal the first valve opening (14e, 14f, 14i) and a second axial position, wherein the valve body is connected to a source of a fire suppression agent comprising a fire suppression agent at a fire suppression agent pressure, and wherein the piston is moveable within the body to a first axial position when the fire suppression agent pressure is less than the pneumatic pressure, and wherein the piston is configured to be withdrawn from the first valve opening only when the fire suppression agent pressure is greater than the pneumatic pressure such that the fire suppression agent can enter the valve body through the first valve opening.
A terminal apparatus comprising: a reception unit adapted to receive a PDCCH including downlink control information; and a transmission unit adapted to transmit a set of four PUSCHes in a bundle including a transport block in consecutive subframes including an uplink subframe and a special subframe, based on detection of the PDCCH, wherein the transmission unit is adapted to trigger non-adaptive retransmission without waiting for a feedback for a preceding transmission in a bundle, when a parameter TTIbundling of an RRC layer is configured to be TRUE, a size of the transport block is given at least based on whether the parameter TTIbundling of the RRC layer is configured to be TRUE, when the parameter TTIbundling of the RRC layer is not configured to be TRUE, the size of the transport block is given at least based on which one of an Uplink Pilot Time Slot, UpPTS, of the special subframe and the uplink subframe is used for transmitting the transport block, when the parameter TTIbundling of the RRC layer is configured to be TRUE, the size of the transport block is given regardless of which one of the uplink subframe and the UpPTS is used for transmitting the transport block, and the parameter TTIbundling indicates whether or not subframe bundling operation is configured. a reception unit adapted to receive a PDCCH including downlink control information; and a transmission unit adapted to transmit a set of four PUSCHes in a bundle including a transport block in consecutive subframes including an uplink subframe and a special subframe, based on detection of the PDCCH, wherein the transmission unit is adapted to trigger non-adaptive retransmission without waiting for a feedback for a preceding transmission in a bundle, when a parameter TTIbundling of an RRC layer is configured to be TRUE, a size of the transport block is given at least based on whether the parameter TTIbundling of the RRC layer is configured to be TRUE, when the parameter TTIbundling of the RRC layer is not configured to be TRUE, the size of the transport block is given at least based on which one of an Uplink Pilot Time Slot, UpPTS, of the special subframe and the uplink subframe is used for transmitting the transport block, when the parameter TTIbundling of the RRC layer is configured to be TRUE, the size of the transport block is given regardless of which one of the uplink subframe and the UpPTS is used for transmitting the transport block, and the parameter TTIbundling indicates whether or not subframe bundling operation is configured.
A scrolling method of a mobile terminal comprising: displaying a plurality of items on a display screen; receiving a touch input for scrolling the plurality of items along the display screen in a downward direction corresponding to a downward direction of a user's touch; modifying at least a displaying region of a first item of the plurality of items characterised in that an upper edge of the displaying region of the first item remains fixed on the display screen in response to receiving the touch input for scrolling when the plurality of items displayed on the display screen cannot be scrolled further in the downward direction corresponding to the downward direction of the user's touch; and restoring the displaying region of the first item on the display screen. displaying a plurality of items on a display screen; receiving a touch input for scrolling the plurality of items along the display screen in a downward direction corresponding to a downward direction of a user's touch; modifying at least a displaying region of a first item of the plurality of items characterised in that an upper edge of the displaying region of the first item remains fixed on the display screen in response to receiving the touch input for scrolling when the plurality of items displayed on the display screen cannot be scrolled further in the downward direction corresponding to the downward direction of the user's touch; and restoring the displaying region of the first item on the display screen.
Protective helmet comprising a cap which is adapted to be fitted on and around the head of a user, wherein the cap includes an external shell and at least one housing seat for an airbag, wherein at said at least one housing seat the external shell comprises at least a movable portion (103; 103a, 103b, 103c), which is permanently connected to a remaining fixed portion of the external shell, the protective helmet being characterized in that the movable portion (103, 103a, 103b, 103c) is movable between a closed position, in which it covers the at least one housing seat and an airbag housed therein in a deflated condition, and an open position, in which it releases at least partially the at least one housing seat allowing the airbag to expand outside the cap in an inflated condition.
A process for the processing of crystallized salt mixtures containing kainite, which are kainite/sylvin/halite salt mixtures freshly prepared by crystallization, for the preparation of a kainite concentrate fraction and a residue fraction consisting of the residual minerals present in the solid mixture, by means of a one- or multi-stage flotative separation process, characterized in that the crystallized salt mixture is intensively mixed with a conditioning agent combination consisting of a sulfated fatty acid or its alkali salt as collector reagent and a foaming agent known for flotation in a flotation solution and then separated by mechanical or pneumatic flotation into a kainite concentrate fraction and a residue fraction, wherein 250 to 350 g/t solids of the sulfated fatty acid or alkali salts thereof are used as collectors, and the flotation temperature is 25°C to 80°C. the crystallized salt mixture is intensively mixed with a conditioning agent combination consisting of a sulfated fatty acid or its alkali salt as collector reagent and a foaming agent known for flotation in a flotation solution and then separated by mechanical or pneumatic flotation into a kainite concentrate fraction and a residue fraction, wherein 250 to 350 g/t solids of the sulfated fatty acid or alkali salts thereof are used as collectors, and the flotation temperature is 25°C to 80°C.
A cutoff holder, comprising - a plate-type holder body which includes a cutting tool seat, and - a clamping section for clamping the cutoff holder into a machine tool, wherein - at least one first cooling lubricant channel is disposed in the holder body, said first cooling lubricant channel including at least one exit opening (18a, 18b) on a lateral surface (122") of the holder body and exiting the lateral surface (122") at an angle, - wherein the exit opening (18a, 18b) is aligned in such a manner that a cooling lubricant jet which exits the cooling lubricant channel can be directed towards a surface of a cutting tool from the side, said cutting tool being received in the cutting tool seat, characterized in that the holder body - comprises at least one upper cooling lubricant channel which ends in an upper exit opening, said exit opening being disposed on a front face of the holder body and being aligned in such a manner that a cooling lubricant jet exiting the cooling lubricant channel can be directed towards a cutting edge of a cutting tool from above, said cutting tool being received in the cutting tool seat, and - comprises at least one lower cooling lubricant channel which ends in a lower exit opening, said exit opening being disposed on a front face of the holder body and being aligned in such a manner that a cooling lubricant jet exiting the cooling lubricant channel can be directed towards the cutting edge of the cutting tool from below, said cutting tool being received in the cutting tool seat. - a plate-type holder body which includes a cutting tool seat, and - a clamping section for clamping the cutoff holder into a machine tool, wherein - at least one first cooling lubricant channel is disposed in the holder body, said first cooling lubricant channel including at least one exit opening (18a, 18b) on a lateral surface (122") of the holder body and exiting the lateral surface (122") at an angle, - wherein the exit opening (18a, 18b) is aligned in such a manner that a cooling lubricant jet which exits the cooling lubricant channel can be directed towards a surface of a cutting tool from the side, said cutting tool being received in the cutting tool seat, - comprises at least one upper cooling lubricant channel which ends in an upper exit opening, said exit opening being disposed on a front face of the holder body and being aligned in such a manner that a cooling lubricant jet exiting the cooling lubricant channel can be directed towards a cutting edge of a cutting tool from above, said cutting tool being received in the cutting tool seat, and - comprises at least one lower cooling lubricant channel which ends in a lower exit opening, said exit opening being disposed on a front face of the holder body and being aligned in such a manner that a cooling lubricant jet exiting the cooling lubricant channel can be directed towards the cutting edge of the cutting tool from below, said cutting tool being received in the cutting tool seat.