An exchanger for medical use comprising: - a box-like body having a base, an opposite upper end, a peripheral wall and inside which a thermal exchange chamber is defined, delimited by an internal surface of the peripheral wall, said body having: - at least one first entrance aperture of a fluid to be thermo-regulated and a first exit of thermo-regulated fluid; - a second delivery aperture of a thermo-regulator fluid and a second exit of said thermo-regulated fluid; - a heat exchange element by lapping that is housed in said exchange chamber and retained between two holding elements (13, 14) and which divides said exchange chamber into a zone where the thermo-regulator fluid flows and a zone where the fluid to be thermo-regulated flows and which are fluid-dynamically separated from each other; - a collecting compartment of air separated from said fluid to be thermo-regulated, obtained in said opposite end and connected to said exchange chamber and equipped with an aperture communicating with the outside, said box-like body defining a second housing chamber for a pumping group and in fluid-dynamical connection with said heat exchange chamber, said heat exchange element comprising a lamellar body that shapes a plurality of contiguous ribs and which has overall a cylindrical/three-dimensional shape and defines said flow passage zones of said thermo-regulator fluid and said passage zones of said fluid to be thermo-regulated, fluid-dynamically separated from each other, wherein said lamellar body is folded in accordion fashion, characterized in that said lamellar body comprises spacer means interposed between the ribs. - a box-like body having a base, an opposite upper end, a peripheral wall and inside which a thermal exchange chamber is defined, delimited by an internal surface of the peripheral wall, said body having: - at least one first entrance aperture of a fluid to be thermo-regulated and a first exit of thermo-regulated fluid; - a second delivery aperture of a thermo-regulator fluid and a second exit of said thermo-regulated fluid; - a heat exchange element by lapping that is housed in said exchange chamber and retained between two holding elements (13, 14) and which divides said exchange chamber into a zone where the thermo-regulator fluid flows and a zone where the fluid to be thermo-regulated flows and which are fluid-dynamically separated from each other; - a collecting compartment of air separated from said fluid to be thermo-regulated, obtained in said opposite end and connected to said exchange chamber and equipped with an aperture communicating with the outside, said box-like body defining a second housing chamber for a pumping group and in fluid-dynamical connection with said heat exchange chamber, said heat exchange element comprising a lamellar body that shapes a plurality of contiguous ribs and which has overall a cylindrical/three-dimensional shape and defines said flow passage zones of said thermo-regulator fluid and said passage zones of said fluid to be thermo-regulated, fluid-dynamically separated from each other, wherein said lamellar body is folded in accordion fashion, characterized in that said lamellar body comprises spacer means interposed between the ribs.