mhurhangee/ep-ind-claims huggingface dataset:
An addition-fragmentation agent of the formula: wherein R 1, R 2 and R 3 are each independently Z m -Q-, a (hetero)alkyl group or a (hetero)aryl group with the proviso that at least one of R 1, R 2 and R 3 is Z m -Q-, Q is a linking group have a valence of m +1; Z is an ethylenically unsaturated polymerizable group selected from and wherein R 4 is H or C 1 -C 4 alkyl, m is 1 to 6; each X 1 is independently -O- or -NR 4 -, where R 4 is H or C 1 -C 4 alkyl, and n is 0 or 1, and Q is selected from -O-, -S-, -NR 4 -, -SO 2 -, -PO 2 -, -CO-, -OCO-, -R 6 -, and combinations thereof, wherein each R 4 is hydrogen, a C 1 to C 4 alkyl group, or aryl group, each R 6 is an alkylene group having 1 to 6 carbon atoms, a 5- or 6-membered cycloalkylene group having 5 to 10 carbon atoms, or a divalent arylene group having 6 to 16 carbon atoms, with the proviso that Q-Z does not contain peroxidic linkages, wherein the peroxidic linkages are O-O, N-O, S-O, N-N and N-S; or Q is selected from an alkylene or a hydroxyl-substituted alkylene or an aryloxy-substituted alkylene. R 1, R 2 and R 3 are each independently Z m -Q-, a (hetero)alkyl group or a (hetero)aryl group with the proviso that at least one of R 1, R 2 and R 3 is Z m -Q-, Q is a linking group have a valence of m +1; Z is an ethylenically unsaturated polymerizable group selected from and wherein R 4 is H or C 1 -C 4 alkyl, m is 1 to 6; each X 1 is independently -O- or -NR 4 -, where R 4 is H or C 1 -C 4 alkyl, and n is 0 or 1, and Q is selected from -O-, -S-, -NR 4 -, -SO 2 -, -PO 2 -, -CO-, -OCO-, -R 6 -, and combinations thereof, wherein each R 4 is hydrogen, a C 1 to C 4 alkyl group, or aryl group, each R 6 is an alkylene group having 1 to 6 carbon atoms, a 5- or 6-membered cycloalkylene group having 5 to 10 carbon atoms, or a divalent arylene group having 6 to 16 carbon atoms, with the proviso that Q-Z does not contain peroxidic linkages, wherein the peroxidic linkages are O-O, N-O, S-O, N-N and N-S; or Q is selected from an alkylene or a hydroxyl-substituted alkylene or an aryloxy-substituted alkylene.
A heat exchanger comprising: a core section defining a plurality of first fluid channels and a plurality of second fluid channels; a header section defining a plurality of first fluid layers and a plurality of second fluid layers; and a transition region located between the header section and the core section, the transition region fluidly coupling the plurality of first fluid layers to the first fluid channels, each of the first fluid layers routing a first fluid to a respective group of first fluid channels; wherein: at least one of the first fluid layers is centrally aligned with a first row of first fluid channels to route the first fluid to all of the channels of the first row and to route the first fluid to a portion of a first adjacent row of first fluid channels and to a portion of a second adjacent row of first fluid channels; and characterised in that the portion of the first adjacent row and the second adjacent row is half of the channels of the first and second adjacent row (44, 46). a core section defining a plurality of first fluid channels and a plurality of second fluid channels; a header section defining a plurality of first fluid layers and a plurality of second fluid layers; and a transition region located between the header section and the core section, the transition region fluidly coupling the plurality of first fluid layers to the first fluid channels, each of the first fluid layers routing a first fluid to a respective group of first fluid channels; wherein: at least one of the first fluid layers is centrally aligned with a first row of first fluid channels to route the first fluid to all of the channels of the first row and to route the first fluid to a portion of a first adjacent row of first fluid channels and to a portion of a second adjacent row of first fluid channels; and characterised in that the portion of the first adjacent row and the second adjacent row is half of the channels of the first and second adjacent row (44, 46). at least one of the first fluid layers is centrally aligned with a first row of first fluid channels to route the first fluid to all of the channels of the first row and to route the first fluid to a portion of a first adjacent row of first fluid channels and to a portion of a second adjacent row of first fluid channels; and characterised in that the portion of the first adjacent row and the second adjacent row is half of the channels of the first and second adjacent row (44, 46).
A seal for a vane seal system, comprising: a seal member configured to be received in a pocket at one end of an airfoil of a non-rotatable vane segment, the seal member including a seal element configured to seal against a mating rotatable seal element and at least one spring portion affixed to the seal element and configured to positively locate the seal element in a sealing direction; wherein the at least one spring portion includes a first spring portion configured to bias the seal member in a first direction and a second spring portion configured to bias the seal member in a second, different direction, wherein the first direction and the second direction are orthogonal; characterised in that the seal member includes a base wall with a spring leg at one end thereof and a second spring leg at an opposed end thereof; wherein the spring leg is configured to positively locate the seal member radially in a radial direction and the second spring leg is configured to bias the seal member in an axial direction. wherein the at least one spring portion includes a first spring portion configured to bias the seal member in a first direction and a second spring portion configured to bias the seal member in a second, different direction, wherein the first direction and the second direction are orthogonal; characterised in that the seal member includes a base wall with a spring leg at one end thereof and a second spring leg at an opposed end thereof; wherein the spring leg is configured to positively locate the seal member radially in a radial direction and the second spring leg is configured to bias the seal member in an axial direction.
Bucket for transporting and unloading products, especially intended for fruit and vegetables, comprising an opening at the top for receiving the products and a collapsible hinged lid at the bottom of the bucket, the lid being connected to actuation means (3 to 6) capable of moving the lid between a closed and an open position for the unloading of the products by means of gravity, the actuation means comprising at least an articulated tilting lever capable of rotation on a turn axis of the bucket and coupled at its opposite end to the lid by mutual sliding fitting means, the lever further being stressed by resilient means, characterized in that the lid comprises at least a side support wall in motion with said lid and positioned adjacent to an inner wall of the bucket, said support wall being intended to drive the products outward by means of friction during the opening motion of the lid, and in that the lid is actuated in a controlled manner by said actuation means (3 to 6) all along its opening path and subsequent closing path.
A method for diagnosis and monitoring of cancer in an individual tumor from a patient, the method comprising: obtaining a cell-free nucleic acid sample from the patient; using a selector set to enrich by hybrid selection for ctDNA that corresponds to the regions of the genome that are most likely to contain tumor-specific somatic mutations; amplifying and sequencing the selected ctDNA to determine which of the selected genomic regions are mutated in the individual tumor; optionally comparing the sequence of the selected ctDNA with the individual's germline DNA sequence to distinguish somatic mutations present in the individual tumor; detecting the tumor-specific mutation in the cell-free nucleic acid sample; and reporting results of detecting the presence of a tumor to the patient. obtaining a cell-free nucleic acid sample from the patient; using a selector set to enrich by hybrid selection for ctDNA that corresponds to the regions of the genome that are most likely to contain tumor-specific somatic mutations; amplifying and sequencing the selected ctDNA to determine which of the selected genomic regions are mutated in the individual tumor; optionally comparing the sequence of the selected ctDNA with the individual's germline DNA sequence to distinguish somatic mutations present in the individual tumor; detecting the tumor-specific mutation in the cell-free nucleic acid sample; and reporting results of detecting the presence of a tumor to the patient.
Locking device for a pivotally articulated front panel of a motor vehicle, comprising at least one panel lock which cooperates with at least one locking bracket arranged on the front panel, a fork latch and a pawl being rotatably mounted in the housing of the panel lock, and at least one spring device which raises the front panel by a defined measurement in the unlocked state being provided between a fixed body part and the front panel, the spring device being integrated in the panel lock (12; 58), the rotatably mounted fork latch having a peripheral support base, characterised in that the support base is formed by a hub portion integrally formed on the fork latch and via which the fork latch is supported, in the locked state, on a corresponding housing projection in the housing of the panel lock in order to absorb forces in the opening direction of the front panel, and in that the hub portion of the fork latch cooperates with a microswitch integrated in the housing of the panel lock in such a way that said switch emits an electrical switching signal to an electrical display device when the fork latch is locked or unlocked.
Fireplace insert, and fireplace stove containing a combustion chamber, a door, an outer convection jacket, and between the combustion chamber and the outer convection jacket an over-door space is located, which is separated from a flow channel of a flue duct, wherein an over-door ventilation flap enabling regulated flow of heated air in the over-door space is pivotally mounted in the over-door space and the air flowing in the over-door space is the air from the heated space characterized in that the ventilation flap is interconnected with the door by means of a gearing, wherein the movement of the ventilation flap from an open position to a closed position is ensured by the movement of the door from a closed position to an open position and the movement of the ventilation flap from a closed position to an open position is ensured by the movement of the door from an open position to a closed position.
A reducing gas generator for startup and shutdown of a fuel cell, comprising: an oxidant source structured to supply a low oxygen (O 2) content oxidant, the low O 2 content oxidant having an O 2 content less than that of atmospheric air; a fuel input configured to receive a hydrocarbon fuel; a merging chamber in fluid communication with said oxidant source and in fluid communication with said fuel inlet, said merging chamber structured to receive the hydrocarbon fuel and the low oxygen (O 2) content oxidant and to discharge a feed mixture containing both the hydrocarbon fuel and the low oxygen (O 2) content oxidant; a catalytic reactor in fluid communication with said merging chamber, said catalytic reactor structured to receive the feed mixture and to catalytically convert the feed mixture into a reducing gas; and a reducing gas output fluidly coupled to said catalytic reactor and in fluid communication with at least one of an anode and a reformer of the fuel cell, said reducing gas output operative to direct the reducing gas to said at least one of the anode and the reformer of the fuel cell, the reducing gas generator further including a control system configured to execute program instructions to regulate a control temperature by varying both the O 2 content of the low O 2 content oxidant and the oxidant/fuel ratio of the feed mixture. an oxidant source structured to supply a low oxygen (O 2) content oxidant, the low O 2 content oxidant having an O 2 content less than that of atmospheric air; a fuel input configured to receive a hydrocarbon fuel; a merging chamber in fluid communication with said oxidant source and in fluid communication with said fuel inlet, said merging chamber structured to receive the hydrocarbon fuel and the low oxygen (O 2) content oxidant and to discharge a feed mixture containing both the hydrocarbon fuel and the low oxygen (O 2) content oxidant; a catalytic reactor in fluid communication with said merging chamber, said catalytic reactor structured to receive the feed mixture and to catalytically convert the feed mixture into a reducing gas; and a reducing gas output fluidly coupled to said catalytic reactor and in fluid communication with at least one of an anode and a reformer of the fuel cell, said reducing gas output operative to direct the reducing gas to said at least one of the anode and the reformer of the fuel cell,
A bicycle pedal comprising a tube, assembled to freely rotate around an axis, and a pedal body comprising at least one first face on which a cyclist is capable of exerting an effort, wherein the pedal body comprises a first portion and a second portion, fastened to the first portion, the tube being arranged between the first and second portions, the first and second portions being separated from the tube by an interstice, characterized by the pedal body being connected to the central tube by at least one connecting member comprising a first portion interposed between the tube and the first face and fitted with at least one deformation gauge, the pedal body not being in direct contact with the tube.
Use of non-human mammalian mammary epithelial cells for enhancing the binding of the Fc region of an IgG antibody or IgG antibodies to an FcγRIII receptor compared to a cell culture-derived antibody or antibodies, wherein said cells are of a non-human mammal engineered to express the antibody in its milk and wherein the glycosylation pattern of the antibody is modified by producing the antibody or antibodies in the cells.
A resin powder for solid freeform fabrication, comprising: resin particles having a significantly pillar-like form, including resin particles having a concave portion on a circumferential side surface, wherein the resin powder has a repose angle measured according to the description of 55 degrees or less. resin particles having a significantly pillar-like form, including resin particles having a concave portion on a circumferential side surface, wherein the resin powder has a repose angle measured according to the description of 55 degrees or less.
A retaining ring for use in a gas turbine engine, the retaining ring comprising: a rotating disc face; and a cover plate face; wherein the retaining ring has a split ring construction and forms an end gap between end gap portions, and wherein at least one of the rotating disc face and the cover plate face includes a stress reducing feature proximal to an end gap portion, characterised in that the stress reducing feature is a scalloped surface. a rotating disc face; and a cover plate face; wherein the retaining ring has a split ring construction and forms an end gap between end gap portions, and wherein at least one of the rotating disc face and the cover plate face includes a stress reducing feature proximal to an end gap portion, characterised in that the stress reducing feature is a scalloped surface.
A breathing apparatus having at least one processor and a touch screen, preferably a multi touch screen, communicatively coupled to said processor, wherein said processor is configured to provide a user interface on said touch screen for modification of at least one operational parameter of said breathing apparatus, said user interface including at least two simultaneously displayed touch sensitive display areas (40, 50) for user modification of said at least one operational parameter, wherein each of the at least two touch sensitive display areas (40, 50) are provided for different types of touch based user interaction modes for modification of the same operational parameter, and wherein modification of said operational parameter is effected in response to touching any of said display areas (40, 50), characterised in that a first of the at least two simultaneously displayed touch sensitive display areas of said interface comprises first input elements for stepwise modification of said at least one operational parameter upon user touch within said first display area, allowing for precise adjustment of said operational parameter, and a second of the at least two simultaneously displayed touch sensitive display areas of said interface comprises second input elements for selection of a particular value from a displayed range of values of said at least one operational parameter upon user touch within said second display area, allowing for quick but coarse adjustment of said at least one operational parameter.
A motorcycle tire comprising: a tread portion, a toroidal carcass, and a tread reinforcement disposed radially outside the carcass in the tread portion, wherein the tread reinforcement includes a band layer, the band layer is composed of a jointless band ply made of a band cord spirally wound at an angle (θa) of not more than 5 degrees with respect to the tire circumferential direction, the tread portion has a tread profile comprising a pair of shoulder arcs portions (Ps) having a radius R2 of curvature, and a crown arc portion (Pc) having a radius R1 of curvature and extending between the shoulder arcs portions (Ps) across the tire equator, and in a normal state of the tire in which the tire is mounted on a regular rim and inflated to a normal tire pressure, axial ends of the crown arc portion (Pc) are respectively located axially inward of axial edges of the jointless band ply. characterized in that the jointless band ply is centered on the tire equator and has a developed width (Wa) of not more than 65% of a developed tread width, the radius R1 of curvature is less than the radius R2 of curvature, and the radius R1 of curvature is less than 50% of the tire section width (Wt). a tread portion, a toroidal carcass, and a tread reinforcement disposed radially outside the carcass in the tread portion, wherein the tread reinforcement includes a band layer, the band layer is composed of a jointless band ply made of a band cord spirally wound at an angle (θa) of not more than 5 degrees with respect to the tire circumferential direction, the tread portion has a tread profile comprising a pair of shoulder arcs portions (Ps) having a radius R2 of curvature, and a crown arc portion (Pc) having a radius R1 of curvature and extending between the shoulder arcs portions (Ps) across the tire equator, and in a normal state of the tire in which the tire is mounted on a regular rim and inflated to a normal tire pressure, axial ends of the crown arc portion (Pc) are respectively located axially inward of axial edges of the jointless band ply. characterized in that the jointless band ply is centered on the tire equator and has a developed width (Wa) of not more than 65% of a developed tread width, the radius R1 of curvature is less than the radius R2 of curvature, and the radius R1 of curvature is less than 50% of the tire section width (Wt).
Method for operating a transmission system that comprises a first network and at least one further network, wherein data are interchanged between these at least two networks (2, 3) by virtue of data of the first network being supplied to duplicating means, wherein the supplied data are split into two data streams by the duplicating means and are wirelessly transmitted to separating means via at least two transmission links (6, 7) by means of the parallel redundancy protocol, PRP, and forwarded to the connected further network by the separating means, wherein the data are transmitted as data packets and it is ascertained whether or not a data packet was transmitted, and this is taken as a basis for deducing whether or not the transmission system is operating correctly.
A method comprising: positioning, using a computer, a sled (200, 420, 510, 1030) underneath a fuselage of an aircraft (310, 410, 530), wherein the sled is positioned at the center of mass of the aircraft; expanding the sled to grip the fuselage to prevent the aircraft from sliding or rotating about the center of mass thereof; levitating the sled (200, 420, 510, 1030) above the ground surface using magnetic forces generated by a high-density permanent magnet array; measuring a distance between the sled (200, 420, 510, 1030) and the ground surface; actively adjusting the magnetic forces generated by the high-density permanent magnet array to keep the distance between the sled (200, 420, 510, 1030) and the ground surface within a desired range; and activating a series of magnets within an electromagnetic catapult to independently accelerate the sled along a desired path on the ground surface by creating a moving magnetic field and levitate the sled above one or more rails. positioning, using a computer, a sled (200, 420, 510, 1030) underneath a fuselage of an aircraft (310, 410, 530), wherein the sled is positioned at the center of mass of the aircraft; expanding the sled to grip the fuselage to prevent the aircraft from sliding or rotating about the center of mass thereof; levitating the sled (200, 420, 510, 1030) above the ground surface using magnetic forces generated by a high-density permanent magnet array; measuring a distance between the sled (200, 420, 510, 1030) and the ground surface; actively adjusting the magnetic forces generated by the high-density permanent magnet array to keep the distance between the sled (200, 420, 510, 1030) and the ground surface within a desired range; and activating a series of magnets within an electromagnetic catapult to independently accelerate the sled along a desired path on the ground surface by creating a moving magnetic field and levitate the sled above one or more rails.