A system adapted to facilitate percutaneous access to a target treatment location within bone, the introducer system comprising: an introducer cannula comprising a proximal handle and a distal elongate hypotube extending from the proximal handle; and an introducer stylet comprising a proximal handle and a distal elongate shaft extending from the proximal handle, wherein the proximal handle of the introducer cannula comprises a central opening in its upper surface that is coupled to a lumen of the distal elongate hypotube to facilitate insertion of the introducer stylet into the central opening and into the distal elongate hypotube, wherein the proximal handle of the introducer cannula comprises one or more slots configured to receive at least a portion of the proximal handle of the introducer stylet so as to facilitate engagement and alignment between the introducer stylet and the introducer cannula, wherein the proximal handle of the introducer stylet comprises an anti-rotation tab configured to be received within one of the one or more slots so as to prevent rotation of the introducer stylet within the introducer cannula, and wherein a distal end of the distal elongate shaft of the introducer stylet comprises a distal cutting tip and a scalloped section proximal to the distal cutting tip so as to provide gaps between an outer diameter of the distal end of the distal elongate shaft and the inner diameter of the introducer cannula, and wherein the proximal handle of the introducer stylet further comprises a press button that is integrally coupled to the anti-rotation tab such that pressing the press button extends the anti-rotation tab out of a constraint of the one or more slots of the proximal handle of the introducer cannula to (a) disengage the anti-rotation tab and allow for rotation of the introducer stylet within the introducer cannula, and (b) allow for removal of the introducer stylet from the introducer cannula. an introducer cannula comprising a proximal handle and a distal elongate hypotube extending from the proximal handle; and an introducer stylet comprising a proximal handle and a distal elongate shaft extending from the proximal handle, wherein the proximal handle of the introducer cannula comprises a central opening in its upper surface that is coupled to a lumen of the distal elongate hypotube to facilitate insertion of the introducer stylet into the central opening and into the distal elongate hypotube, wherein the proximal handle of the introducer cannula comprises one or more slots configured to receive at least a portion of the proximal handle of the introducer stylet so as to facilitate engagement and alignment between the introducer stylet and the introducer cannula, wherein the proximal handle of the introducer stylet comprises an anti-rotation tab configured to be received within one of the one or more slots so as to prevent rotation of the introducer stylet within the introducer cannula, and wherein a distal end of the distal elongate shaft of the introducer stylet comprises a distal cutting tip and a scalloped section proximal to the distal cutting tip so as to provide gaps between an outer diameter of the distal end of the distal elongate shaft and the inner diameter of the introducer cannula, and wherein the proximal handle of the introducer stylet further comprises a press button that is integrally coupled to the anti-rotation tab such that pressing the press button extends the anti-rotation tab out of a constraint of the one or more slots of the proximal handle of the introducer cannula to (a) disengage the anti-rotation tab and allow for rotation of the introducer stylet within the introducer cannula, and (b) allow for removal of the introducer stylet from the introducer cannula.