A catheter assembly comprising: a catheter adapter and a catheter coupled thereto, said catheter adapter having a proximal opening, a distal opening, and a first lumen extending from the proximal opening to the distal opening; a blood control septum positioned within the first lumen and dividing the fluid pathway into a forward chamber and a rearward chamber; a septum actuator slidably positioned within the first lumen within the rearward chamber proximal to the septum, the septum actuator configured to insert into a self-sealing slit of the septum to provide a pathway therethrough when separate Luer devices are inserted into the proximal opening of the catheter adapter, the septum actuator having a body with a tip at a distal end, a base at a proximal end, and a compression compensator which comprises a compressible and resilient material wherein the base comprises a rigid polymer material that is configured to be contacted by the external device that is inserted into the proximal opening of the catheter adapter, the compression compensator positioned between the tip and the base, the septum actuator including a second lumen that extends between the tip and the base through the base, the compression compensator, and the tip, wherein the compression compensator defines a portion of the second lumen such that fluid flowing through the second lumen contacts an inner surface of the compression compensator; wherein a spring constant of the compression compensator is selected such that the compression of the compression compensator absorbs variations in the insertion depth of the tip through the slit in the septum due to variation in insertion depth of the external Luer devices. a catheter adapter and a catheter coupled thereto, said catheter adapter having a proximal opening, a distal opening, and a first lumen extending from the proximal opening to the distal opening; a blood control septum positioned within the first lumen and dividing the fluid pathway into a forward chamber and a rearward chamber; a septum actuator slidably positioned within the first lumen within the rearward chamber proximal to the septum, the septum actuator configured to insert into a self-sealing slit of the septum to provide a pathway therethrough when separate Luer devices are inserted into the proximal opening of the catheter adapter, the septum actuator having a body with a tip at a distal end, a base at a proximal end, and a compression compensator which comprises a compressible and resilient material wherein the base comprises a rigid polymer material that is configured to be contacted by the external device that is inserted into the proximal opening of the catheter adapter, the compression compensator positioned between the tip and the base, the septum actuator including a second lumen that extends between the tip and the base through the base, the compression compensator, and the tip, wherein the compression compensator defines a portion of the second lumen such that fluid flowing through the second lumen contacts an inner surface of the compression compensator; wherein a spring constant of the compression compensator is selected such that the compression of the compression compensator absorbs variations in the insertion depth of the tip through the slit in the septum due to variation in insertion depth of the external Luer devices.