mhurhangee/ep-ind-claims huggingface dataset:
Pharmaceutical composition with improved stability for topical application for the treatment of rhinitis, wherein the composition is an aqueous composition and wherein the said composition contains: a) at least one imidazoline-based alpha-sympathomimetic or its physiologically acceptable salt, wherein the imidazoline-based alpha-sympathomimetic is selected from xylometazoline, and wherein the composition comprises the component a) in an amount of 0.02 to 1.0 wt.-% based on the composition; b) pantothenol (dexpanthenol), wherein the composition contains the component b) in an amount of 0.5 to 8 wt.-% based on the composition; and c) at least one preserving agent and/or disinfecting agent, wherein the preserving agent and/or disinfecting agent is selected from benzalkonium chloride and wherein the composition contains the component c) in an amount of 0.001 to 10 wt.-% based on the composition; wherein the pH value of the composition is set and/or kept constant in the range 5.2 to 5.9, wherein the setting and/or keeping constant of the pH value of the composition is effected by means of at least one chemical buffering system, wherein a dihydrogen phosphate/disodium phosphate buffer system ("H 2 PO 4 - /HPO 4 2- buffer (system)" or "phosphate buffer (system)") is used as the chemical buffering system, wherein the composition has a content of degradation product(s) of the active substance a) of at most 2 wt.-%, based on the active ingredient a), even after storage of the composition at temperatures in the range from 20 °C to 50 °C, at a pressure of 1013.25 mbar and at a relative humidity in the range of 50% to 90% for at least 6 months, and wherein the composition has a content of degradation product(s) of the active agent b) of at most 5 wt.-%, based on the active ingredient b), even after storage of the composition at temperatures in the range from 20 °C to 50 °C, at a pressure of 1013.25 mbar and at a relative humidity in the range of 50% to 90% for at least 6 months. a) at least one imidazoline-based alpha-sympathomimetic or its physiologically acceptable salt, wherein the imidazoline-based alpha-sympathomimetic is selected from xylometazoline, and wherein the composition comprises the component a) in an amount of 0.02 to 1.0 wt.-% based on the composition; b) pantothenol (dexpanthenol), wherein the composition contains the component b) in an amount of 0.5 to 8 wt.-% based on the composition; and c) at least one preserving agent and/or disinfecting agent, wherein the preserving agent and/or disinfecting agent is selected from benzalkonium chloride and wherein the composition contains the component c) in an amount of 0.001 to 10 wt.-% based on the composition;
A pail pack including a strap guide wherein the strap guide comprises: a first module including a first base, a strap boss formed on the first base and including a first slot through which a strap passes, and at least one protrusion accommodation part located at an outer circumferential portion of the strap boss and including a bore; and a second module having a second base, a second slot formed in the second base, and at least one coupling protrusion located at an outer circumferential portion of the second slot and configured to form a pair with the protrusion accommodation part, wherein the first module and the second module are coupled or separated through an accommodation space part of the pail pack to form an opening having a single closed surface, wherein the pail pack comprises two or more accommodation space parts each configured to accommodate the strap guide, wherein the accommodation space part includes a center space part into which the strap boss is fitted, and an upper space part and a lower space part into which the protrusion accommodation part is fitted, and the strap guide is fitted into the accommodation space part, characterized in that the first module is disposed between an inner paper tube and an outer paper tube of the pail pack having the inner paper tube and the outer paper tube, and the second module passes through the accommodation space part formed in the outer paper tube from the outer side of the outer paper tube to be coupled to the first module. a first module including a first base, a strap boss formed on the first base and including a first slot through which a strap passes, and at least one protrusion accommodation part located at an outer circumferential portion of the strap boss and including a bore; and a second module having a second base, a second slot formed in the second base, and at least one coupling protrusion located at an outer circumferential portion of the second slot and configured to form a pair with the protrusion accommodation part, wherein the first module and the second module are coupled or separated through an accommodation space part of the pail pack to form an opening having a single closed surface, wherein the pail pack comprises two or more accommodation space parts each configured to accommodate the strap guide, wherein the accommodation space part includes a center space part into which the strap boss is fitted, and an upper space part and a lower space part into which the protrusion accommodation part is fitted, and the strap guide is fitted into the accommodation space part, characterized in that the first module is disposed between an inner paper tube and an outer paper tube of the pail pack having the inner paper tube and the outer paper tube, and the second module passes through the accommodation space part formed in the outer paper tube from the outer side of the outer paper tube to be coupled to the first module.
A system for treating a fracture in a bone comprising: a bone plate configured to engage the bone, the bone plate comprising a proximal end, a distal end, a head portion, a neck portion and a shaft portion, wherein the head portion comprises a first row of holes and a second row of holes for receiving one or more fasteners therein, wherein the shaft portion comprises at least one additional hole for receiving a fastener therein; a plurality of fasteners received in the head portion and positioned in the first row of holes and/or second row of holes; and at least one fastener received in the shaft portion and positioned in the at least one additional hole, wherein the neck portion includes a threaded instrument attachment hole and a plurality of indentations adjacent the instrument attachment hole, wherein the plurality of indentations and the instrument attachment hole are configured to cooperate with an aiming guide to couple the aiming guide to the bone plate, wherein the first row of holes comprises four holes and the second row of holes comprises four holes, the first row of holes being the most proximal row of holes and the holes of the first row of holes being designed to be positioned adjacent the proximal end of the bone plate, and wherein the holes in the first row of holes are smaller in size than the holes in the second row of holes. a bone plate configured to engage the bone, the bone plate comprising a proximal end, a distal end, a head portion, a neck portion and a shaft portion, wherein the head portion comprises a first row of holes and a second row of holes for receiving one or more fasteners therein, wherein the shaft portion comprises at least one additional hole for receiving a fastener therein; a plurality of fasteners received in the head portion and positioned in the first row of holes and/or second row of holes; and at least one fastener received in the shaft portion and positioned in the at least one additional hole, wherein the neck portion includes a threaded instrument attachment hole and a plurality of indentations adjacent the instrument attachment hole, wherein the plurality of indentations and the instrument attachment hole are configured to cooperate with an aiming guide to couple the aiming guide to the bone plate, wherein the first row of holes comprises four holes and the second row of holes comprises four holes, the first row of holes being the most proximal row of holes and the holes of the first row of holes being designed to be positioned adjacent the proximal end of the bone plate, and wherein the holes in the first row of holes are smaller in size than the holes in the second row of holes.
A lighting device comprising: - a flexible printed circuit elongated in a longitudinal direction and including a plurality of mounting portions spaced apart along said longitudinal direction and connected to each other by deformation portions, and - a plurality of electrically powered light radiation sources fixed to said mounting portions, wherein an encapsulation layer (52, 52', 52'') of cross-linked polymeric material covers said flexible printed circuit and said light radiation source, wherein said polymeric material is dispensed in liquid form and subsequently crosslinked and wherein said encapsulation layer (52, 52', 52'') has a first thickness at said mounting portions and a second thickness smaller than said first thickness at said deformation portions, wherein least one through opening is formed through said encapsulation layer (52, 52', 52'') at one or more of said deformation portions and wherein one or more of said deformation portions of said flexible printed circuit comprise at least two conductive tracks spaced apart in a transverse direction and wherein said at least one through opening is located between said conductive tracks. - a flexible printed circuit elongated in a longitudinal direction and including a plurality of mounting portions spaced apart along said longitudinal direction and connected to each other by deformation portions, and - a plurality of electrically powered light radiation sources fixed to said mounting portions, wherein an encapsulation layer (52, 52', 52'') of cross-linked polymeric material covers said flexible printed circuit and said light radiation source, wherein said polymeric material is dispensed in liquid form and subsequently crosslinked and wherein said encapsulation layer (52, 52', 52'') has a first thickness at said mounting portions and a second thickness smaller than said first thickness at said deformation portions, wherein least one through opening is formed through said encapsulation layer (52, 52', 52'') at one or more of said deformation portions and wherein one or more of said deformation portions of said flexible printed circuit comprise at least two conductive tracks spaced apart in a transverse direction and wherein said at least one through opening is located between said conductive tracks.
A neo chordae tendinae deployment system, comprising: a catheter having a proximal end and a distal end; a helical ventricular anchor subassembly extendable through the catheter, the ventricular anchor subassembly comprising: a hub, a ventricular suture extending proximally from the hub; a helical anchor extending distally from the hub; a core wire extending concentrically through the helical anchor, and beyond the distal end of the helical anchor, and a flexible, tubular sleeve extending proximally from the hub, wherein the flexible, tubular sleeve extending proximally from the hub has a length of no more than about 10 cm; and J a leaflet anchor deployment subassembly extendable through the catheter, having a radially enlargeable leaflet anchor within the subassembly and having a leaflet suture Z extending proximally through the catheter. a catheter having a proximal end and a distal end; a helical ventricular anchor subassembly extendable through the catheter, the ventricular anchor subassembly comprising: a hub, a ventricular suture extending proximally from the hub; a helical anchor extending distally from the hub; a core wire extending concentrically through the helical anchor, and beyond the distal end of the helical anchor, and a flexible, tubular sleeve extending proximally from the hub, wherein the flexible, tubular sleeve extending proximally from the hub has a length of no more than about 10 cm; and J a leaflet anchor deployment subassembly extendable through the catheter, having a radially enlargeable leaflet anchor within the subassembly and having a leaflet suture Z extending proximally through the catheter. a hub, a ventricular suture extending proximally from the hub; a helical anchor extending distally from the hub; a core wire extending concentrically through the helical anchor, and beyond the distal end of the helical anchor, and a flexible, tubular sleeve extending proximally from the hub, wherein the flexible, tubular sleeve extending proximally from the hub has a length of no more than about 10 cm; and J a leaflet anchor deployment subassembly extendable through the catheter, having a radially enlargeable leaflet anchor within the subassembly and having a leaflet suture Z extending proximally through the catheter.
Method of fabricating a microscale imaging system, comprising the steps of: - providing a substrate; - forming, by means of a 3D-printing technique, a 3D-structure on the substrate, wherein: the forming of the 3D-structure comprises forming a stack of at least two diffractive optical elements in a single printing step; characterized in that the 3D-printing technique comprises exposing a photoresist being deposited on the substrate, the exposing comprising guiding an exposing beam, such that a plurality of writing tracks (40a, 40b) are written on a plurality of individual writing layers (50a-50c); and the diffractive optical elements have edge structures being formed in that an additional edge optimizing track is written on an upper boundary of desired edge structures, and/or a target track is omitted on a lower boundary of the desired edge structures. - providing a substrate; - forming, by means of a 3D-printing technique, a 3D-structure on the substrate, wherein: the forming of the 3D-structure comprises forming a stack of at least two diffractive optical elements in a single printing step; characterized in that the 3D-printing technique comprises exposing a photoresist being deposited on the substrate, the exposing comprising guiding an exposing beam, such that a plurality of writing tracks (40a, 40b) are written on a plurality of individual writing layers (50a-50c); and the diffractive optical elements have edge structures being formed in that an additional edge optimizing track is written on an upper boundary of desired edge structures, and/or a target track is omitted on a lower boundary of the desired edge structures. the forming of the 3D-structure comprises forming a stack of at least two diffractive optical elements in a single printing step; characterized in that the 3D-printing technique comprises exposing a photoresist being deposited on the substrate, the exposing comprising guiding an exposing beam, such that a plurality of writing tracks (40a, 40b) are written on a plurality of individual writing layers (50a-50c); and the diffractive optical elements have edge structures being formed in that an additional edge optimizing track is written on an upper boundary of desired edge structures, and/or a target track is omitted on a lower boundary of the desired edge structures.
A separator comprising a housing, a separator chamber contained within the housing, a dividing member substantially dividing the separator chamber into a first chamber and a second chamber, an inlet and outlet to the first chamber, a flow path (38, 42, 44) provided between the first and second chambers (30,32) for allowing flow to circulate from the first chamber to the second chamber, and from the second chamber to the first chamber, characterised in that a flow guide is provided for creating opposing flow paths in the second chamber by passing some of the flow over the top of the flow guide and the rest of the flow impinging on the flow guide and being forced to change direction, the opposing flow paths meeting in an area of the second chamber where the flow in each path is substantially towards opposing flow in the other path, for slowing flow through the second chamber, and flow in the first chamber between the inlet and the outlet is substantially unrestricted.
A method for manufacturing surface enhanced Raman spectroscopy (SERS) tags comprising the steps: a) providing a first colloid consisting essentially of nanoparticles having a plasmonic surface and substantially same size dispersed in an aqueous solvent, and a stabilizing agent adsorbed on the surface of said nanoparticles, and having a ζ-potential value lower than or equal to -25 mV; b) providing a second colloid consisting essentially of nanoparticles having a plasmonic surface and substantially same size dispersed in an aqueous solvent, Raman active reporter molecules adsorbed on the surface of said nanoparticles, and a stabilizing agent adsorbed on the surface of said nanoparticles, and having a ζ-potential value lower than or equal to -25 mV; c) combining the first colloid with the second colloid so that the ratio between the number of nanoparticles of the first colloid and the number of nanoparticles of the second colloid is of between 25: 1 to 1: 1, preferably from 5: 1 to 1: 1 to provide a third colloid; d) inducing aggregation of the nanoparticles by any of the steps d1) - d2) or a combination thereof: d1) mixing the third colloid obtained at step c) at a pH comprised between 2.2 and the lowest pH value at which the Raman active reporter molecules have a net electrical charge of between 0 and 0.3; d2) addition of a salt solution, preferably an inorganic salt solution, to the third colloid obtained at step c); and e) stopping aggregation. a) providing a first colloid consisting essentially of nanoparticles having a plasmonic surface and substantially same size dispersed in an aqueous solvent, and a stabilizing agent adsorbed on the surface of said nanoparticles, and having a ζ-potential value lower than or equal to -25 mV; b) providing a second colloid consisting essentially of nanoparticles having a plasmonic surface and substantially same size dispersed in an aqueous solvent, Raman active reporter molecules adsorbed on the surface of said nanoparticles, and a stabilizing agent adsorbed on the surface of said nanoparticles, and having a ζ-potential value lower than or equal to -25 mV; c) combining the first colloid with the second colloid so that the ratio between the number of nanoparticles of the first colloid and the number of nanoparticles of the second colloid is of between 25: 1 to 1: 1, preferably from 5: 1 to 1: 1 to provide a third colloid; d) inducing aggregation of the nanoparticles by any of the steps d1) - d2) or a combination thereof: d1) mixing the third colloid obtained at step c) at a pH comprised between 2.2 and the lowest pH value at which the Raman active reporter molecules have a net electrical charge of between 0 and 0.3; d2) addition of a salt solution, preferably an inorganic salt solution, to the third colloid obtained at step c); and d1) mixing the third colloid obtained at step c) at a pH comprised between 2.2 and the lowest pH value at which the Raman active reporter molecules have a net electrical charge of between 0 and 0.3; d2) addition of a salt solution, preferably an inorganic salt solution, to the third colloid obtained at step c); and e) stopping aggregation.
A method for a data transmission process of a Machine Type Communication, MTC, device, characterized in that the method comprises: determining, at a network side, a scheme of transmitting a small data amount of user data on a control plane for the MTC device; and instructing, at the network side, the MTC device to transmit a small data amount of user data on the control plane in the determined scheme; wherein the scheme of transmitting a small data amount of user data on a control plane for the MTC device includes any one or combination of the following contents: whether to allow the MTC device to transmit a small data amount of data in the scheme of transmitting user data on the control plane; the size of a small data amount of data allowed to be transmitted by the MTC device; signalling allowed to be used by the MTC device to transmit a small data amount of data; a correspondence relationship between signalling allowed to be used by the MTC device to transmit a small data amount of data and a limited size of a small data amount of data allowed to be carried in the signalling; information on the type of a terminal device allowed to transmit a small data amount of data in the scheme of transmitting user data on the control plane; and information on an attribute of a terminal device allowed to transmit a small data amount of data in the scheme of transmitting user data on the control plane. determining, at a network side, a scheme of transmitting a small data amount of user data on a control plane for the MTC device; and instructing, at the network side, the MTC device to transmit a small data amount of user data on the control plane in the determined scheme; whether to allow the MTC device to transmit a small data amount of data in the scheme of transmitting user data on the control plane; the size of a small data amount of data allowed to be transmitted by the MTC device; signalling allowed to be used by the MTC device to transmit a small data amount of data; a correspondence relationship between signalling allowed to be used by the MTC device to transmit a small data amount of data and a limited size of a small data amount of data allowed to be carried in the signalling; information on the type of a terminal device allowed to transmit a small data amount of data in the scheme of transmitting user data on the control plane; and information on an attribute of a terminal device allowed to transmit a small data amount of data in the scheme of transmitting user data on the control plane.
A packaged semiconductor structure, comprising: an interconnect layer (52, 275); a first microelectronic device (40, 270) on a first major surface of the interconnect layer (52, 275); a substrate (10, 250) having a cavity (12, 111), wherein the cavity (12, 111) is defined by a vertical portion (13, 15) and a horizontal portion, wherein the vertical portion (13, 15) surrounds the first microelectronic device (40, 270), the horizontal portion is over the first microelectronic device (40, 270), and the first microelectronic device (40, 270) is between the horizontal portion and the first major surface of the interconnect layer (52, 275) such that the first device is in the cavity (12, 111); a second microelectronic device (24, 242) attached to the horizontal portion of the substrate (10, 250); and an encapsulant (50, 272) on the interconnect layer (52, 275) and surrounding the first microelectronic device (40, 270), the substrate (10, 250), and the second microelectronic device (24, 242), such that the substrate (10, 250) is embedded in the encapsulant (50, 272); and characterized by a plurality of interconnects (16, 22) on the vertical portion (13, 15) of the substrate (10, 250), wherein the encapsulant (50, 272) exposes a portion of each interconnect (16, 22) of the plurality of interconnects. an interconnect layer (52, 275); a first microelectronic device (40, 270) on a first major surface of the interconnect layer (52, 275); a substrate (10, 250) having a cavity (12, 111), wherein the cavity (12, 111) is defined by a vertical portion (13, 15) and a horizontal portion, wherein the vertical portion (13, 15) surrounds the first microelectronic device (40, 270), the horizontal portion is over the first microelectronic device (40, 270), and the first microelectronic device (40, 270) is between the horizontal portion and the first major surface of the interconnect layer (52, 275) such that the first device is in the cavity (12, 111); a second microelectronic device (24, 242) attached to the horizontal portion of the substrate (10, 250); and an encapsulant (50, 272) on the interconnect layer (52, 275) and surrounding the first microelectronic device (40, 270), the substrate (10, 250), and the second microelectronic device (24, 242), such that the substrate (10, 250) is embedded in the encapsulant (50, 272); and characterized by a plurality of interconnects (16, 22) on the vertical portion (13, 15) of the substrate (10, 250), wherein the encapsulant (50, 272) exposes a portion of each interconnect (16, 22) of the plurality of interconnects.