A handset for an electroporation device, the handset comprising: a housing defining a volume therein; a circuit board at least partially positioned within the volume; one or more electrodes extending from the housing and in electrical communication with the circuit board; and a battery pack including: a battery pack housing, a plurality of battery cells positioned within the battery pack housing, a first power lead in electrical communication with the circuit board, a second power lead coupled to the plurality of battery cells and in electrical communication with the circuit board, and a safety switch positioned within the battery pack housing and coupled between the first power lead and the plurality of battery cells, wherein the safety switch is adjustable between an ON state, where the plurality of battery cells are in electrical communication with the first power lead, and an OFF state, where the plurality of battery cells are not in electrical communication with the first power lead, and a power switch positioned within the battery pack housing, wherein the power switch is accessible from outside the battery pack housing and is adjustable between an ON state and an OFF state, and wherein the safety switch is adjustable between its ON state and its OFF state based at least in part on the state of the power switch. a housing defining a volume therein; a circuit board at least partially positioned within the volume; one or more electrodes extending from the housing and in electrical communication with the circuit board; and a battery pack including: a battery pack housing, a plurality of battery cells positioned within the battery pack housing, a first power lead in electrical communication with the circuit board, a second power lead coupled to the plurality of battery cells and in electrical communication with the circuit board, and a safety switch positioned within the battery pack housing and coupled between the first power lead and the plurality of battery cells, wherein the safety switch is adjustable between an ON state, where the plurality of battery cells are in electrical communication with the first power lead, and an OFF state, where the plurality of battery cells are not in electrical communication with the first power lead, and a power switch positioned within the battery pack housing, wherein the power switch is accessible from outside the battery pack housing and is adjustable between an ON state and an OFF state, and wherein the safety switch is adjustable between its ON state and its OFF state based at least in part on the state of the power switch. a battery pack housing, a plurality of battery cells positioned within the battery pack housing, a first power lead in electrical communication with the circuit board, a second power lead coupled to the plurality of battery cells and in electrical communication with the circuit board, and a safety switch positioned within the battery pack housing and coupled between the first power lead and the plurality of battery cells, wherein the safety switch is adjustable between an ON state, where the plurality of battery cells are in electrical communication with the first power lead, and an OFF state, where the plurality of battery cells are not in electrical communication with the first power lead, and a power switch positioned within the battery pack housing, wherein the power switch is accessible from outside the battery pack housing and is adjustable between an ON state and an OFF state, and wherein the safety switch is adjustable between its ON state and its OFF state based at least in part on the state of the power switch.