An apparatus for coupling a liquid chromatography column having an end fitting to a length of tubing, the apparatus comprising at least one body member defining at least one chamber having at least one spring therein and a pushing and latching mechanism configured to seal an end of the tubing against the column end fitting, wherein: the at least one body member comprises: a proximal body member having a first end configured to mate with the column end fitting and a second end; an intermediate body member comprising an intermediate body member first end attached to the second end of the proximal body member and an intermediate body member second end; and a distal body member attached to the intermediate body member second end; the at least one chamber comprises: a first chamber bounded by the intermediate body member and the distal body member; and a second chamber bounded by the intermediate body member and the proximal body member; the at least one spring comprises a first spring within the first chamber, the first spring configured so as to apply a first force to the length of tubing towards the column end fitting through a ferrule; and a second spring within the second chamber, the second spring configured to apply a second force to a deformable sealing member towards the column end fitting, wherein the second force is capable of deforming the deformable sealing member so as to form a leak-free seal against the column end fitting; and the pushing and latching mechanism is configured to push the at least one body member, the first spring and the second spring towards the column end fitting. the at least one body member comprises: a proximal body member having a first end configured to mate with the column end fitting and a second end; an intermediate body member comprising an intermediate body member first end attached to the second end of the proximal body member and an intermediate body member second end; and a distal body member attached to the intermediate body member second end; a proximal body member having a first end configured to mate with the column end fitting and a second end; an intermediate body member comprising an intermediate body member first end attached to the second end of the proximal body member and an intermediate body member second end; and a distal body member attached to the intermediate body member second end; the at least one chamber comprises: a first chamber bounded by the intermediate body member and the distal body member; and a second chamber bounded by the intermediate body member and the proximal body member; a first chamber bounded by the intermediate body member and the distal body member; and a second chamber bounded by the intermediate body member and the proximal body member; the at least one spring comprises a first spring within the first chamber, the first spring configured so as to apply a first force to the length of tubing towards the column end fitting through a ferrule; and a second spring within the second chamber, the second spring configured to apply a second force to a deformable sealing member towards the column end fitting, wherein the second force is capable of deforming the deformable sealing member so as to form a leak-free seal against the column end fitting; and the pushing and latching mechanism is configured to push the at least one body member, the first spring and the second spring towards the column end fitting. a first spring within the first chamber, the first spring configured so as to apply a first force to the length of tubing towards the column end fitting through a ferrule; and a second spring within the second chamber, the second spring configured to apply a second force to a deformable sealing member towards the column end fitting, wherein the second force is capable of deforming the deformable sealing member so as to form a leak-free seal against the column end fitting; and the pushing and latching mechanism is configured to push the at least one body member, the first spring and the second spring towards the column end fitting.