An interspinous distractor device, in particular for arthrodesis, comprising: - a main distractor body (2, 201), apt to be inserted between two adjacent spinous processes to provide a relative support; - a first (31, 32) and a second (33, 34) pair of lateral stabilizers, arranged spaced apart along a longitudinal direction of said main body; - support means (41, 42) of each of said pairs of stabilizers, which support means are slidable with respect to said main body along said longitudinal direction, wherein the stabilizers of each pair (31-32, 33-34) are rotatably connected to a respective support means (41, 42) according to respective axes perpendicular to said longitudinal direction and wherein said stabilizers of each pair (31-32, 33-34) are slidable integrally to said respective support means (41, 42); - actuation means of said lateral stabilizers, percutaneously operable to determine a rotation and a subsequent translation of said stabilizers with respect to said main body, which actuation means comprises a threaded shaft rotatable about an axis extending along said longitudinal direction, which threaded shaft presents a first and a second thread longitudinally spaced apart and opposed, each thread being configured for mating with a respective pair of stabilizers (31-32, 33-34), each of said stabilizers having engagement means suitable to said mating with a respective thread (51, 52), wherein the overall arrangement is such that each stabilizer is rotatably movable with respect to said main body between a first closed configuration, in which the stabilizers realize a compact configuration which facilitates the percutaneous insertion of the device, and a second open configuration, in which the stabilizers are open wide, and wherein the overall arrangement is also such that each stabilizer is slidably movable between said second open configuration and a third retaining configuration, in which the open-wide stabilizers of the first pair are longitudinally juxtaposed to respective open-wide stabilizers of the second pair so as to abut a spinous process; and - control means suitable to determine the passage from said second configuration to said third configuration, which control means comprises an end-of-stroke element of a movement of opening wide of said stabilizers, which end-of-stroke element is realized at said support means (41, 42). - a main distractor body (2, 201), apt to be inserted between two adjacent spinous processes to provide a relative support; - a first (31, 32) and a second (33, 34) pair of lateral stabilizers, arranged spaced apart along a longitudinal direction of said main body; - support means (41, 42) of each of said pairs of stabilizers, which support means are slidable with respect to said main body along said longitudinal direction, wherein the stabilizers of each pair (31-32, 33-34) are rotatably connected to a respective support means (41, 42) according to respective axes perpendicular to said longitudinal direction and wherein said stabilizers of each pair (31-32, 33-34) are slidable integrally to said respective support means (41, 42); - actuation means of said lateral stabilizers, percutaneously operable to determine a rotation and a subsequent translation of said stabilizers with respect to said main body, which actuation means comprises a threaded shaft rotatable about an axis extending along said longitudinal direction, which threaded shaft presents a first and a second thread longitudinally spaced apart and opposed, each thread being configured for mating with a respective pair of stabilizers (31-32, 33-34), each of said stabilizers having engagement means suitable to said mating with a respective thread (51, 52), wherein the overall arrangement is such that each stabilizer is rotatably movable with respect to said main body between a first closed configuration, in which the stabilizers realize a compact configuration which facilitates the percutaneous insertion of the device, and a second open configuration, in which the stabilizers are open wide, and wherein the overall arrangement is also such that each stabilizer is slidably movable between said second open configuration and a third retaining configuration, in which the open-wide stabilizers of the first pair are longitudinally juxtaposed to respective open-wide stabilizers of the second pair so as to abut a spinous process; and - control means suitable to determine the passage from said second configuration to said third configuration, which control means comprises an end-of-stroke element of a movement of opening wide of said stabilizers, which end-of-stroke element is realized at said support means (41, 42).