mhurhangee/ep-ind-claims huggingface dataset:
Use of compound IL-12 for the manufacture of a medicament for treating a disease state in a human, wherein the treatment comprises: (a) administering a treatment to the human that is intended to target the disease state, wherein the treatment comprises chemotherapy, radiation therapy, or a combination thereof, and the treatment has an associated hematopoietic toxicity; and (b) administering one or more therapeutically effective dose(s) of IL-12 24 hours or less before administration of the treatment, or 24 hours or less after administration of the treatment, wherein the effective dose(s) are 1 ng/kg up to 500 ng/kg of IL-12, and wherein administration of IL-12 to the human reduces the hematopoietic toxicity of the treatment. (a) administering a treatment to the human that is intended to target the disease state, wherein the treatment comprises chemotherapy, radiation therapy, or a combination thereof, and the treatment has an associated hematopoietic toxicity; and (b) administering one or more therapeutically effective dose(s) of IL-12 24 hours or less before administration of the treatment, or 24 hours or less after administration of the treatment, wherein the effective dose(s) are 1 ng/kg up to 500 ng/kg of IL-12, and wherein administration of IL-12 to the human reduces the hematopoietic toxicity of the treatment.
A turbocharger (120, 200) comprising: a center housing (280, 380, 480, 580, 880, 1380) that comprises a through bore (281, 381, 881, 1381) and a stepped locating pin socket (285, 385, 485, 585, 885, 1385) that comprises a step from a smaller diameter pin portion to a larger diameter seating portion, wherein the step forms a stop surface (887, 1387) defined by a smaller inner diameter and a larger outer diameter of the stepped locating pin socket; a bearing (230, 430, 530, 830, 1330) disposed in the through bore wherein the bearing comprises an opening (235, 835, 1335); and a stepped locating pin (210, 410, 510, 610, 810, 1310), wherein the stepped locating pin comprises a step from a smaller diameter pin portion (612, 812, 1312), received in part in the pin portion of the stepped locating pin socket and in part by the opening of the bearing, to a larger diameter seating portion (614, 814, 1314), secured via an interference fit in the seating portion of the stepped locating pin socket, wherein the step of the stepped locating pin forms a stop surface (617, 817, 1317) that contacts the stop surface of the stepped locating pin socket to axially position the stepped locating pin in the stepped locating pin socket. a center housing (280, 380, 480, 580, 880, 1380) that comprises a through bore (281, 381, 881, 1381) and a stepped locating pin socket (285, 385, 485, 585, 885, 1385) that comprises a step from a smaller diameter pin portion to a larger diameter seating portion, wherein the step forms a stop surface (887, 1387) defined by a smaller inner diameter and a larger outer diameter of the stepped locating pin socket; a bearing (230, 430, 530, 830, 1330) disposed in the through bore wherein the bearing comprises an opening (235, 835, 1335); and a stepped locating pin (210, 410, 510, 610, 810, 1310), wherein the stepped locating pin comprises a step from a smaller diameter pin portion (612, 812, 1312), received in part in the pin portion of the stepped locating pin socket and in part by the opening of the bearing, to a larger diameter seating portion (614, 814, 1314), secured via an interference fit in the seating portion of the stepped locating pin socket, wherein the step of the stepped locating pin forms a stop surface (617, 817, 1317) that contacts the stop surface of the stepped locating pin socket to axially position the stepped locating pin in the stepped locating pin socket.
A power controller that is provided in a consumer having a load equipment and is configured to control an operation of the load equipment, comprising: an acquisition unit that is configured to acquire a plurality of operation modes for determining an operation status of the load equipment, or is configured to acquire operation parameters configuring each of the plurality of operation modes and being for controlling the load equipment; a setting unit that is configured to add or reconfigure any of the plurality of operation modes of the load equipment; a provisional operation control unit that is configured to perform a provisional operation of the load equipment sequentially on the basis of the plurality of operation modes, the provisional operation is an operation where all operation modes are sequentially instructed and different from an actual operation; a measurement unit that is configured to measure, for each of the plurality of operation modes, a provisional power consumption consumed by the load equipment, during the provisional operation of the load equipment; a storage unit that is configured to store the provisional power consumption measured by the measurement unit associating with the operation mode applied when measuring the provisional power consumption; and a power control unit that is configured to control an operation of the load equipment on the basis of the provisional power consumption for each of the plurality of operation modes stored in the storage unit. an acquisition unit that is configured to acquire a plurality of operation modes for determining an operation status of the load equipment, or is configured to acquire operation parameters configuring each of the plurality of operation modes and being for controlling the load equipment; a setting unit that is configured to add or reconfigure any of the plurality of operation modes of the load equipment; a provisional operation control unit that is configured to perform a provisional operation of the load equipment sequentially on the basis of the plurality of operation modes, the provisional operation is an operation where all operation modes are sequentially instructed and different from an actual operation; a measurement unit that is configured to measure, for each of the plurality of operation modes, a provisional power consumption consumed by the load equipment, during the provisional operation of the load equipment; a storage unit that is configured to store the provisional power consumption measured by the measurement unit associating with the operation mode applied when measuring the provisional power consumption; and a power control unit that is configured to control an operation of the load equipment on the basis of the provisional power consumption for each of the plurality of operation modes stored in the storage unit.
Battery charging device for inductive charging, in particular dynamic and/or stationary inductive charging, of a traction battery of a vehicle that is able to be driven on the ground, in particular a ground-based industrial truck, comprising charging modules, which are arranged next to one another and are driven over by the vehicle, in each of which at least one primary coil is arranged, which is able to transmit electrical power to a secondary coil of the vehicle such that the traction battery is able to be charged while the vehicle is driving over, wherein the charging modules are able to be placed on the ground and comprise at least one initial module and at least one end module, characterized in that the at least one initial module and the at least one end module each have a ramp (3, 4), by way of which the vehicle is able to drive onto/off the charging modules from/onto the ground.
A device for supporting metal samples including: - a frame; - a series of suspension of samples (6, 40) attached on the frame via a block of insulating material; said device being characterized in that it includes: - a series of reference electrodes mounted on the frame via blocks of insulating material; - at least one bar for maintaining the samples, said bar including housings in which are received an end of the samples. - a frame; - a series of suspension of samples (6, 40) attached on the frame via a block of insulating material; said device being characterized in that it includes: - a series of reference electrodes mounted on the frame via blocks of insulating material; - at least one bar for maintaining the samples, said bar including housings in which are received an end of the samples.
LED module comprising a plurality of LEDs (76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89) which are arranged on a printed circuit board and which each have a "bedding element" with a lens (100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113) with which the respective LED (76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89) protrudes from the printed circuit board plane, wherein the LEDs (76 to 89) are each coupled to a light input element (30, 31, 32, 33) of an optical waveguide body and the respective associated light input element (30, 31, 32, 33) radiates the respective luminous flux from the associated LED (76 to 89) outwards from the LED module, characterized in that the printed circuit board for the LEDs (76 to 89) has at least one passive LED (95, 96, 97) provided on it which can be activated if one of the LEDs (76 to 89) fails, and in that the luminous flux (arrows 3 and 4) emitted by the passive LED (95, 96, 97) shines into the light input element (30, 31, 32, 33) of the failed LED (76 to 89) and is radiated outwards via the light input element (30, 31, 32, 33).
A method for monitoring the etch uniformity of a plasma etching process for removing a layer of material from a substrate, the method comprising the steps of: - generating a plasma thereby progressively removing material from said layer, said plasma emitting light and wherein no other light source is provided besides said plasma, - measuring one or more spectral components of light by an optical detection means (10,11,12) at a lateral location, - detecting oscillations of at least one of said spectral components as a function of time, said oscillations being caused by detected light interference patterns which change due to the progressive removal of material from said layer, characterised in that: • the plasma is generated in an area between said layer and a counter-surface mounted opposite said layer and substantially parallel to said layer, wherein the lateral location is lateral with respect to said area, and wherein said one or more spectral components of light are emitted from said area, • the size and material of the counter surface, the size and material of the substrate and the layer, and the distance between the layer and the counter electrode are configured so that said interference patterns are primarily due to reflections of light beams taking place in said area between the layer and the counter surface, said light beams being directed according to the Brewster angle of the material of the counter surface, • an indication about the etch uniformity is derived from said oscillations. - generating a plasma thereby progressively removing material from said layer, said plasma emitting light and wherein no other light source is provided besides said plasma, - measuring one or more spectral components of light by an optical detection means (10,11,12) at a lateral location, - detecting oscillations of at least one of said spectral components as a function of time, said oscillations being caused by detected light interference patterns which change due to the progressive removal of material from said layer, • the plasma is generated in an area between said layer and a counter-surface mounted opposite said layer and substantially parallel to said layer, wherein the lateral location is lateral with respect to said area, and wherein said one or more spectral components of light are emitted from said area, • the size and material of the counter surface, the size and material of the substrate and the layer, and the distance between the layer and the counter electrode are configured so that said interference patterns are primarily due to reflections of light beams taking place in said area between the layer and the counter surface, said light beams being directed according to the Brewster angle of the material of the counter surface, • an indication about the etch uniformity is derived from said oscillations.
Process for the preparation of a glazed ceramic body, in which (a) a glazing material is applied to a non-densely sintered substrate material having a relative density in the range of from 30 to 90%, based on the true density of the substrate material, and (b) the substrate material and the glazing material are subjected to a heat treatment in a temperature range which extends from a first temperature T 1, at which the substrate material begins to sinter, to a second temperature T 2, which is higher than the first temperature and at which the substrate material has a relative density of at least 97%, based on the true density of the substrate material, in order to obtain the glazed body, wherein, at the temperature T 1, the glazing material has a viscosity of more than 10 2.5 Pa.s, in particular more than 10 4.0 Pa.s, preferably more than 10 5.6 Pa·s and particularly preferably more than 10 7.0 Pa·s and, at the temperature T 2, a viscosity of less than 10 9 Pa.s, in particular less than 10 7 Pa·s and preferably less than 10 5.6 Pa.s. (a) a glazing material is applied to a non-densely sintered substrate material having a relative density in the range of from 30 to 90%, based on the true density of the substrate material, and (b) the substrate material and the glazing material are subjected to a heat treatment in a temperature range which extends from a first temperature T 1, at which the substrate material begins to sinter, to a second temperature T 2, which is higher than the first temperature and at which the substrate material has a relative density of at least 97%, based on the true density of the substrate material, in order to obtain the glazed body,
Fluid line element for a fluid line, in particular in a motor vehicle, comprising at least one connection device for an attachment member, comprising at least one fluid channel, at least one attachment member channel and comprising at least one attachment member, wherein - the attachment member channel branches off from the fluid channel, - the cross-section of the attachment member channel being smaller than the cross-section of the fluid channel, - wherein the cross-section of the attachment member channel is designed to be constant or varying along its extension, wherein in the case of a varying cross-section the cross-section is constantly smaller than the cross-section of the fluid channel, - the connection device is designed as a receptacle for a sensor, characterized in that - the attachment member channel has at least one deflection in its course, and in that - the attachment member channel runs at least partially in the fluid line element and at least partially in the attachment member. - the attachment member channel branches off from the fluid channel, - the cross-section of the attachment member channel being smaller than the cross-section of the fluid channel, - wherein the cross-section of the attachment member channel is designed to be constant or varying along its extension, wherein in the case of a varying cross-section the cross-section is constantly smaller than the cross-section of the fluid channel, - the connection device is designed as a receptacle for a sensor, - the attachment member channel has at least one deflection in its course, and in that - the attachment member channel runs at least partially in the fluid line element and at least partially in the attachment member.
Laboratory automated system for processing sample tubes, the system comprising - a conveyor and a plurality of work cells (30, 31, 32, 33, 34, 40) coupled as modules to the conveyor so that sample tubes can be transported by the conveyor to the work cells (30, 31, 32, 33, 34, 40), wherein the work cells (30, 31, 32, 33, 34, 40) have respective sample processing throughputs, - a sample buffer module coupled to the conveyor, the sample buffer module being in common to the plurality of work cells (30, 31, 32, 33, 34, 40), - a sample workflow manager configured to dispatch sample tubes from the sample buffer module to the work cells (30, 31, 32, 33, 34, 40) via the conveyor with a frequency for each work cell (30, 31, 32, 33, 34, 40), which is equal to the sample processing throughput of each respective work cell (30, 31, 32, 33, 34, 40) characterized in that: - at least one of the work cells coupled to the conveyor is an archiving module for storing sample tubes processed by the other work cells (30, 31, 32, 33, 34) or an unloading module coupled to the conveyor for unloading sample tubes from the system, and - the sample workflow manager is further configured to dispatch processed sample tubes from the work cells (30, 31, 32, 33, 34) to the sample buffer module for at least a first predetermined time, during which time additional processing by the same or different work cell (30, 31, 32, 33, 34) may be requested, and to dispatch the processed sample tubes from the sample buffer module to the archiving module or to the unloading module after said first predetermined time. - a conveyor and a plurality of work cells (30, 31, 32, 33, 34, 40) coupled as modules to the conveyor so that sample tubes can be transported by the conveyor to the work cells (30, 31, 32, 33, 34, 40), wherein the work cells (30, 31, 32, 33, 34, 40) have respective sample processing throughputs, - a sample buffer module coupled to the conveyor, the sample buffer module being in common to the plurality of work cells (30, 31, 32, 33, 34, 40), - a sample workflow manager configured to dispatch sample tubes from the sample buffer module to the work cells (30, 31, 32, 33, 34, 40) via the conveyor with a frequency for each work cell (30, 31, 32, 33, 34, 40), which is equal to the sample processing throughput of each respective work cell (30, 31, 32, 33, 34, 40) characterized in that: - at least one of the work cells coupled to the conveyor is an archiving module for storing sample tubes processed by the other work cells (30, 31, 32, 33, 34) or an unloading module coupled to the conveyor for unloading sample tubes from the system, and - the sample workflow manager is further configured to dispatch processed sample tubes from the work cells (30, 31, 32, 33, 34) to the sample buffer module for at least a first predetermined time, during which time additional processing by the same or different work cell (30, 31, 32, 33, 34) may be requested, and to dispatch the processed sample tubes from the sample buffer module to the archiving module or to the unloading module after said first predetermined time.
A method for satellite beam handover management for aircraft in a satellite communication system comprising a plurality of satellite beams, the method comprising: retrieving flight plan data for a plurality of aircraft being provided a network access service for passengers via the satellite communication system; identifying, for each aircraft of the plurality of aircraft based at least in part on the flight plan data, respective candidate satellite beams of the plurality of satellite beams for providing the network access service over a service timeframe; obtaining, for the plurality of satellite beams for the service timeframe, a beam utilization score indicative of predicted beam utilization over the service timeframe; selecting, over the service timeframe, satellite beams for providing the network access service for each aircraft of the plurality of aircraft based at least in part on the beam utilization scores for the respective candidate satellite beams; and scheduling at least one handover for at least one of the plurality of aircraft to a selected satellite beam during the service timeframe. retrieving flight plan data for a plurality of aircraft being provided a network access service for passengers via the satellite communication system; identifying, for each aircraft of the plurality of aircraft based at least in part on the flight plan data, respective candidate satellite beams of the plurality of satellite beams for providing the network access service over a service timeframe; obtaining, for the plurality of satellite beams for the service timeframe, a beam utilization score indicative of predicted beam utilization over the service timeframe; selecting, over the service timeframe, satellite beams for providing the network access service for each aircraft of the plurality of aircraft based at least in part on the beam utilization scores for the respective candidate satellite beams; and scheduling at least one handover for at least one of the plurality of aircraft to a selected satellite beam during the service timeframe.
A turbine, comprising: an outer duct; a turbine casing formed to define a turbine interior, the turbine casing being disposed within the outer duct to define an annulus; a vane element pivotably coupled to the turbine casing via a spindle including a threaded screw that includes a head that extends from the turbine casing and partially through the annulus, the vane element extends in a spanwise dimension into the turbine interior; and a sensor element supportively coupled to the outer duct; wherein the sensor element includes a microwave sensor having a waveguide extending from the outer duct and partially through the annulus, the sensor element senses a linear distance between complementary ends of the waveguide and the head of the threaded screw. an outer duct; a turbine casing formed to define a turbine interior, the turbine casing being disposed within the outer duct to define an annulus; a vane element pivotably coupled to the turbine casing via a spindle including a threaded screw that includes a head that extends from the turbine casing and partially through the annulus, the vane element extends in a spanwise dimension into the turbine interior; and a sensor element supportively coupled to the outer duct; wherein the sensor element includes a microwave sensor having a waveguide extending from the outer duct and partially through the annulus, the sensor element senses a linear distance between complementary ends of the waveguide and the head of the threaded screw.
Method for determining the temperature of a pencil glowplug during operation in an internal combustion engine, in which a temperature-resistance reference correlation (B, F) is determined, characterized in that the temperature-resistance reference correlation (B, F) is acquired from a multiplicity of pencil glowplugs which are not installed in the internal combustion engine, and after the installation of a pencil glowplug (21, 22, 23, 24), selected from the multiplicity, in the internal combustion engine a calibration step is carried out by respectively carrying out a measurement of a resistance value at two different voltages which are applied successively to the pencil glowplug, wherein each measured resistance value from the temperature-resistance reference correlation (B, F) is assigned a temperature value, as a result of which a specific temperature-resistance correlation (II; III) which corresponds to the pencil glowplug (21, 22, 23, 24) installed in the internal combustion engine is acquired and, from which temperature-resistance correlation (II; III) the temperature of the pencil glowplug (21, 22, 23, 24) during the operation of the pencil glowplug (21, 22, 23, 24) in the internal combustion engine is determined.