A high-speed smart cutting and processing center, comprising a cutting machine, a die cutter magazine and a die cutter circulation table, wherein the cutting machine includes a machine base, a working table and a cross beam, where the working table and the cross beam are disposed on the machine base, punch slide rails are disposed on the cross beam, matching punch slide seats are disposed on the punch slide rails respectively, a rotary cutting head is disposed under the punch slide seats, a die cutter fixing plate is disposed at the bottom of the rotary cutting head, a die cutter for cutting and a die cutter clamping and limiting device are disposed at the bottom of the rotary cutting head, the die cutter circulation table is located at the left side of the working table, one end of the die cutter circulation table is connected with the die cutter magazine and the other end is connected with the working table, the die cutter magazine comprises a frame, a die cutter storage rack and a lifting device, where the die cutter storage rack and the lifting device are disposed within the frame, a plurality of die cutters are stacked up and down in different layers in the die cutter storage rack, guide columns are disposed at four corners of the frame, guide sleeves slidably cooperating with the guide columns are disposed on the die cutter storage rack, the lifting device drives the die cutter storage rack to move up and down along the guide columns, the lifting device comprises a motor gear box being disposed on the top of the frame, characterized in that, the motor gear box is provided with a dual-output shaft, driving belt wheels, a driven shaft, driven bearings, driven belt wheels and synchronous belts, wherein two driving belt wheels are respectively disposed on both ends of the output shaft, two driven bearings are fixed at a lower portion of the frame and located below the die cutter storage rack, wherein the driven shaft is penetrated through the two driven bearings, the driven belt wheels are disposed on both ends of the driven shaft, the driving belt wheels drive the driven belt wheels to rotate by the synchronous belts, wherein a synchronous belt is disposed on left and right sides of the frame respectively, and each synchronous belt is provided with a cutter rack fixing plate, one end of the cutter rack fixing plate is fixed on the synchronous belt, and the other end is fixed on the die cutter storage rack at this side, wherein a plurality of slideways for placing the die cutters are disposed up and down at the left and right sides of the die cutter storage rack respectively, a die cutter locking device for positioning the die cutters in the slideways is disposed at the right side of the die cutter storage rack, the die cutter locking device comprises a locking cylinder, a locking operation rod, locking bearings, driving rods, locking rods, locking rod rotary shafts, and a rotary shaft fixing rod, the locking cylinder is fixed on an upper portion of the die cutter storage rack, the locking operation rod is fixedly connected with an output shaft of the locking cylinder, the locking operation rod is penetrated through two locking bearings which are fixed on the die cutter storage rack and respectively located both ends of the locking operation rod, the locking operation rod is slid up and down along the locking bearings under the drive of the locking cylinder, the rotary shaft fixing rod is fixed at a side of the die cutter storage rack, the rotary shaft fixing rod is provided with a plurality of avoiding holes each corresponding to a placement position of the each layer of die cutter, the driving rods, the locking rods and the locking rod rotary shafts are disposed at a side of the placement position of each layer of die cutter respectively by sets, the locking rod is provided with a waist-shaped hole, a rotary shaft hole and a arc-shaped portion respectively, the locking rod rotary shafts are penetrated through the rotary shaft fixing rod and the rotary shaft holes of the locking rods to movably connect the locking rods in the locking rod avoiding holes, one end of the driving rods is fixed on the locking rods, and the other end is movable inserted into the waist-shaped holes of the locking rods, the arc-shaped portions of the locking rods are fitted into limiting grooves of side edges of the die cutters, the locking operation rod slides up and down, so as to drive the locking rods to rotate around the locking rod rotary shafts through the driving rods.