An upper of a shoe comprising: a sock; lateral and medial edge portions (7L and 7M) placed respectively on lateral and medial edges of an opening of the sock, the lateral and medial edge portions (7L and 7M) being less stretchable than a member forming the sock, and defining a plurality of holes through which a shoelace passes, the plurality of holes including four or more holes provided on each of a lateral side and a medial side of a foot; at least one reinforcement member on a lateral side, the at least one reinforcement member being less stretchable than the member forming the sock and extending from the lateral edge portion to a sole or a heel counter while being attached to a lateral-side surface of the sock; and at least one reinforcement member on a medial side, the at least one reinforcement member on the medial side being less stretchable than the member forming the sock and extending from the medial edge portion to the sole or the heel counter while being attached to a medial side surface of the sock, wherein: the at least one reinforcement member on the lateral side includes a first reinforcement portion covering at least a portion of a fifth proximal phalanx from a side surface and a second reinforcement portion covering at least a portion of a shaft or a base of a fifth metatarsal bone from the side surface; and the at least one reinforcement member on the medial side includes a third reinforcement portion covering at least a portion of a ball of a big toe from a side surface and a fourth reinforcement portion covering at least a portion of a navicular bone from the side surface, the fourth reinforcement portion has a width, and a width of the fourth reinforcement portion at a lower end portion thereof is smaller than a width of the fourth reinforcement portion at an upper end portion thereof; the width of the third reinforcement portion is smaller at a lower end portion thereof than at an upper end portion thereof; the width of the second reinforcement portion is smaller at a lower end portion thereof than at an upper end portion thereof; the width of the first reinforcement portion is smaller at a lower end portion thereof than at an upper end portion thereof; characterized in that an area of a medial-side soft region, in which the member forming the sock is exposed, between the third reinforcement portion and the fourth reinforcement portion on the medial-side surface is larger than an area of a lateral-side soft region, in which the member forming the sock is exposed, between the first reinforcement portion and the second reinforcement portion on the lateral-side surface; and a width of each of the reinforcement portions (1 to 4) at the upper end portion thereof is set in such a manner that the upper end portion faces a plurality of holes of the four or more holes on the lateral or medial side. a sock; lateral and medial edge portions (7L and 7M) placed respectively on lateral and medial edges of an opening of the sock, the lateral and medial edge portions (7L and 7M) being less stretchable than a member forming the sock, and defining a plurality of holes through which a shoelace passes, the plurality of holes including four or more holes provided on each of a lateral side and a medial side of a foot; at least one reinforcement member on a lateral side, the at least one reinforcement member being less stretchable than the member forming the sock and extending from the lateral edge portion to a sole or a heel counter while being attached to a lateral-side surface of the sock; and at least one reinforcement member on a medial side, the at least one reinforcement member on the medial side being less stretchable than the member forming the sock and extending from the medial edge portion to the sole or the heel counter while being attached to a medial side surface of the sock, wherein: the at least one reinforcement member on the lateral side includes a first reinforcement portion covering at least a portion of a fifth proximal phalanx from a side surface and a second reinforcement portion covering at least a portion of a shaft or a base of a fifth metatarsal bone from the side surface; and the at least one reinforcement member on the medial side includes a third reinforcement portion covering at least a portion of a ball of a big toe from a side surface and a fourth reinforcement portion covering at least a portion of a navicular bone from the side surface, the fourth reinforcement portion has a width, and a width of the fourth reinforcement portion at a lower end portion thereof is smaller than a width of the fourth reinforcement portion at an upper end portion thereof; the width of the third reinforcement portion is smaller at a lower end portion thereof than at an upper end portion thereof; the width of the second reinforcement portion is smaller at a lower end portion thereof than at an upper end portion thereof; the width of the first reinforcement portion is smaller at a lower end portion thereof than at an upper end portion thereof; characterized in that an area of a medial-side soft region, in which the member forming the sock is exposed, between the third reinforcement portion and the fourth reinforcement portion on the medial-side surface is larger than an area of a lateral-side soft region, in which the member forming the sock is exposed, between the first reinforcement portion and the second reinforcement portion on the lateral-side surface; and a width of each of the reinforcement portions (1 to 4) at the upper end portion thereof is set in such a manner that the upper end portion faces a plurality of holes of the four or more holes on the lateral or medial side.