A reloadable auto-injector comprising: a syringe assembly comprising a syringe with a needle, a housing for accommodation of said syringe assembly, the syringe assembly being movably positioned in the housing between a first position in which position the needle is accommodated inside the housing and a second position in which position the needle protrudes outside the housing, the syringe assembly further comprising: a plunger rod configured to be advanced in the syringe for delivering at least one dose of medicament, a plunger rod driver being configured to apply a force to the plunger rod to advance the plunger rod in the syringe for delivering at least one dose of medicament, the auto-injector further comprising a syringe driver configured to apply a force to the syringe assembly thereby moving the syringe assembly from the first position to the second position, a reload handle configured to reload the auto-injector for injecting a further dose of medicament, wherein the reload handle is connected to the syringe assembly so that user operation of the reload handle is configured to retract the syringe assembly to the first position and to simultaneously reload the syringe driver to thereby ready the auto injector for delivering a further dose of medicament, wherein the syringe driver and the plunger driver are separate driver means, wherein the syringe driver comprises a resilient device, such as a spring, such as a compression spring, the auto-injector further comprising a syringe lock configured to lock the syringe in the first position, and a skin sensor configured to release the syringe lock upon engagement with the skin of a user wherein the skin sensor is activated by pressing the skin sensor onto a user's skin, wherein the activation of the skin sensor is configured to cause an upward movement of the skin sensor whereby a skin sensor angled surface is configured to engage with a syringe lock angled surface translating the lateral motion of the skin sensor into angular motion of the syringe lock, wherein the syringe assembly rests on a ledge in the syringe lock to lock the syringe in the first position and wherein the angular motion of the syringe lock releases the syringe assembly, wherein the syringe assembly comprises a syringe assembly tap, the syringe assembly tap being configured to move in a syringe lock guide slot from a released position adjacent the ledge to a syringe lock end stop wherein the syringe assembly is moved from the first position to the second position when the syringe assembly tab travels in the syringe lock guide slot from the released position to the syringe lock end stop. a syringe assembly comprising a syringe with a needle, a housing for accommodation of said syringe assembly, the syringe assembly being movably positioned in the housing between a first position in which position the needle is accommodated inside the housing and a second position in which position the needle protrudes outside the housing, the syringe assembly further comprising: a plunger rod configured to be advanced in the syringe for delivering at least one dose of medicament, a plunger rod driver being configured to apply a force to the plunger rod to advance the plunger rod in the syringe for delivering at least one dose of medicament, the auto-injector further comprising a syringe driver configured to apply a force to the syringe assembly thereby moving the syringe assembly from the first position to the second position, a reload handle configured to reload the auto-injector for injecting a further dose of medicament, wherein the reload handle is connected to the syringe assembly so that user operation of the reload handle is configured to retract the syringe assembly to the first position and to simultaneously reload the syringe driver to thereby ready the auto injector for delivering a further dose of medicament, wherein the syringe driver and the plunger driver are separate driver means, wherein the syringe driver comprises a resilient device, such as a spring, such as a compression spring, the auto-injector further comprising a syringe lock configured to lock the syringe in the first position, and a skin sensor configured to release the syringe lock upon engagement with the skin of a user wherein the skin sensor is activated by pressing the skin sensor onto a user's skin, wherein the activation of the skin sensor is configured to cause an upward movement of the skin sensor whereby a skin sensor angled surface is configured to engage with a syringe lock angled surface translating the lateral motion of the skin sensor into angular motion of the syringe lock, wherein the syringe assembly rests on a ledge in the syringe lock to lock the syringe in the first position and wherein the angular motion of the syringe lock releases the syringe assembly, wherein the syringe assembly comprises a syringe assembly tap, the syringe assembly tap being configured to move in a syringe lock guide slot from a released position adjacent the ledge to a syringe lock end stop wherein the syringe assembly is moved from the first position to the second position when the syringe assembly tab travels in the syringe lock guide slot from the released position to the syringe lock end stop.