Device to produce personalized mixtures of substances intended to obtain and optimize coffee beverages for a specific individual or user, said device comprising: a plurality of containers containing ground or whole coffee beans, wherein a first variety of ground or whole coffee beans is contained in a first container of the plurality of containers, and a second variety of ground or whole coffee beans is contained in a second container of the plurality of containers; at least a measuring device and a delivery device for delivering ground or whole coffee beans, the delivery device coupled to each container of the plurality of containers and disposed upstream from the measuring device, the delivery device being operatively connected to the measuring device; management and control means comprising verification and control means and a mixture memory storing a plurality of formulas of specific mixtures, the management and control means adapted to control the delivery device to deliver at least one of the first and second varieties of whole or ground coffee beans in a controlled manner to form a personalized mixture of ground or whole coffee beans, the management and control means adapted to extract coffee from the personalized mixture to provide a coffee beverage; a second memory containing compatibility data of specific mixtures, the second memory being disposed in the management and control means and connected to the verification and control means; the management and control means being configured to control the measuring device and to optimize balancing and suitability of the personalized mixture of ground or whole coffee beans based on a comparison with the compatibility data stored in the second memory; an advice and dialogue unit configured to provide a feedback to a specific individual or user based on the comparison performed by the management and control means, wherein said device is associated with the management and control means configured to carry out instructions regarding at least one personalized formula that expresses a univocal sensory profile or profile functional to the specific needs of the specific individual or user; wherein the verification and control means is configured to control the measuring device and to verify and control adequacy, compatibility, and non-interference of the components of the specific mixtures. a plurality of containers containing ground or whole coffee beans, wherein a first variety of ground or whole coffee beans is contained in a first container of the plurality of containers, and a second variety of ground or whole coffee beans is contained in a second container of the plurality of containers; at least a measuring device and a delivery device for delivering ground or whole coffee beans, the delivery device coupled to each container of the plurality of containers and disposed upstream from the measuring device, the delivery device being operatively connected to the measuring device; management and control means comprising verification and control means and a mixture memory storing a plurality of formulas of specific mixtures, the management and control means adapted to control the delivery device to deliver at least one of the first and second varieties of whole or ground coffee beans in a controlled manner to form a personalized mixture of ground or whole coffee beans, the management and control means adapted to extract coffee from the personalized mixture to provide a coffee beverage; a second memory containing compatibility data of specific mixtures, the second memory being disposed in the management and control means and connected to the verification and control means; the management and control means being configured to control the measuring device and to optimize balancing and suitability of the personalized mixture of ground or whole coffee beans based on a comparison with the compatibility data stored in the second memory; an advice and dialogue unit configured to provide a feedback to a specific individual or user based on the comparison performed by the management and control means, wherein said device is associated with the management and control means configured to carry out instructions regarding at least one personalized formula that expresses a univocal sensory profile or profile functional to the specific needs of the specific individual or user; wherein the verification and control means is configured to control the measuring device and to verify and control adequacy, compatibility, and non-interference of the components of the specific mixtures.