mhurhangee/ep-ind-claims huggingface dataset:
A method comprising: communicating data on a configured set of component carriers of a wireless or mobile communications system; detecting a trigger for connection re-establishment. wherein the detecting comprises detecting a radio link failure of a predefined component carrier, wherein the predefined component carrier comprises a primary component carrier of the configured set of component carriers; identifying at least one component carrier in the configured set that can be used for the connection re-establishment; requesting for connection re-establishment through the at least one identified component carrier; and prioritising at least one cell providing at least one of the component carriers of the configured set over other cells available for the connection re-establishment in response to a radio link failure, wherein upon failure of the primary component carrier of the configured set, the at least one of the component carriers of the configured set of component carriers is prioritised for the re-establishment, wherein the cell that corresponds to a component carrier that belongs to the configured set is prioritised over cells that do not belong to the configured set of component carriers. communicating data on a configured set of component carriers of a wireless or mobile communications system; detecting a trigger for connection re-establishment. wherein the detecting comprises detecting a radio link failure of a predefined component carrier, wherein the predefined component carrier comprises a primary component carrier of the configured set of component carriers; identifying at least one component carrier in the configured set that can be used for the connection re-establishment; requesting for connection re-establishment through the at least one identified component carrier; and prioritising at least one cell providing at least one of the component carriers of the configured set over other cells available for the connection re-establishment in response to a radio link failure, wherein upon failure of the primary component carrier of the configured set, the at least one of the component carriers of the configured set of component carriers is prioritised for the re-establishment, wherein the cell that corresponds to a component carrier that belongs to the configured set is prioritised over cells that do not belong to the configured set of component carriers.
A process for the preparation of a compound of formula I, which process comprises reaction of a compound of formula II, wherein: L 1 represents a leaving group, in the presence of: (a) a source of formamidine; or (b) formamide. L 1 represents a leaving group, in the presence of: (a) a source of formamidine; or (b) formamide. (a) a source of formamidine; or (b) formamide.
Heat-sealable barrier paper comprising or consisting of a) a carrier paper having a front side and a back side opposite the front side, b) a first barrier layer disposed on the front side of the carrier paper and consisting of or comprising a binder and a pigment, and c) a second barrier layer disposed on the first barrier layer and consisting of or comprising an acrylate copolymer and a wax, wherein the wax in the second barrier layer comprises or consists of one, two, three or more than three alkanes selected from the group consisting of heneicosane, docosane, tricosane, tetracosane, pentacosane, hexacosane, heptacosane, octacosane, nonacosane, triacontane, hentriacontane, dotriacontane, tritriacontane, tetratriacontane, pentatriacontane, hexatriacontane, heptatriacontane, octatriacontane, and nonatriacontane, wherein the acrylate copolymer in the second barrier layer is a copolymer prepared using two, three, four, five, six or all the monomers selected from the group consisting of methyl acrylate, methyl methacrylate, butyl acrylate, butyl methacrylate, 2-ethylhexyl acrylate, 2-ethylhexyl methacrylate, and styrene and wherein the binder in the first barrier layer is a (meth)acrylate polymer or (meth)acrylate copolymer. a) a carrier paper having a front side and a back side opposite the front side, b) a first barrier layer disposed on the front side of the carrier paper and consisting of or comprising a binder and a pigment, and c) a second barrier layer disposed on the first barrier layer and consisting of or comprising an acrylate copolymer and a wax, wherein the wax in the second barrier layer comprises or consists of one, two, three or more than three alkanes selected from the group consisting of heneicosane, docosane, tricosane, tetracosane, pentacosane, hexacosane, heptacosane, octacosane, nonacosane, triacontane, hentriacontane, dotriacontane, tritriacontane, tetratriacontane, pentatriacontane, hexatriacontane, heptatriacontane, octatriacontane, and nonatriacontane, wherein the acrylate copolymer in the second barrier layer is a copolymer prepared using two, three, four, five, six or all the monomers selected from the group consisting of methyl acrylate, methyl methacrylate, butyl acrylate, butyl methacrylate, 2-ethylhexyl acrylate, 2-ethylhexyl methacrylate, and styrene and wherein the binder in the first barrier layer is a (meth)acrylate polymer or (meth)acrylate copolymer.
A method comprising: detecting in a biological sample from a human patient having or suspected of having cancer the presence of a ROS1 fusion polypeptide having ROS1 kinase activity or a polynucleotide encoding the same; and detecting in the biological sample the presence of a mutant EGFR polypeptide or a polynucleotide encoding the same. detecting in a biological sample from a human patient having or suspected of having cancer the presence of a ROS1 fusion polypeptide having ROS1 kinase activity or a polynucleotide encoding the same; and detecting in the biological sample the presence of a mutant EGFR polypeptide or a polynucleotide encoding the same.
A variable-volume injection valve comprising: a stator having a first port, a second port, and a contact surface with a groove therein, the first port opening into the stator groove; and a rotor having a contact surface with a groove therein, the contact surface of the rotor being urged against the contact surface of the stator such that the rotor groove opposes the stator groove with one end of the rotor groove overlapping the stator groove and the opposite end of the rotor groove overlapping the second port of the stator, the overlapping grooves of the rotor and stator providing a fluidic channel between the first and second ports of the stator, the rotor rotatable with respect to the stator in known increments to vary a volume of the fluidic channel between the first and second ports of the stator by varying a length of overlap between the overlapping rotor and stator grooves (50, 64), wherein each incremental rotation of the rotor exposes a different known length of the rotor groove, thereby varying a volume of injected sample. a stator having a first port, a second port, and a contact surface with a groove therein, the first port opening into the stator groove; and a rotor having a contact surface with a groove therein, the contact surface of the rotor being urged against the contact surface of the stator such that the rotor groove opposes the stator groove with one end of the rotor groove overlapping the stator groove and the opposite end of the rotor groove overlapping the second port of the stator, the overlapping grooves of the rotor and stator providing a fluidic channel between the first and second ports of the stator, the rotor rotatable with respect to the stator in known increments to vary a volume of the fluidic channel between the first and second ports of the stator by varying a length of overlap between the overlapping rotor and stator grooves (50, 64), wherein each incremental rotation of the rotor exposes a different known length of the rotor groove, thereby varying a volume of injected sample.
A method of manufacturing a sole structure for an article of footwear, the sole structure configured to be attached to an upper of the article of footwear, the method comprising: providing a plate within a cavity of a mold, the plate including a base and a rib, the base including a first surface (144, 146) and a second surface (144, 146), the first surface (144, 146) configured to face the upper, the second surface (144, 146) facing away from the first surface (144, 146), the rib projecting from the second surface (144, 146) of the base; providing a preform bladder member within the cavity of the mold, the preform bladder member including a first member (182, 184) and a second member (182, 184); forming a bladder from the first member (182, 184) and the second member (182, 184) using the mold, the bladder including an interior chamber (140, 188, 194) configured to contain a fluid; and attaching the first member (182, 184) to the plate using the mold, wherein attaching the first member (182, 184) to the plate includes shaping the first member (182, 184) according to surfaces of the rib.
An electrosurgical forceps, comprising a housing and; a shaft having a proximal end which is received within the housing, and an end effector assembly disposed at a distal end of the shaft, the end effector assembly including a first jaw member and a second jaw member; a drive assembly operably coupled to the end effector assembly and configured to move at least one of the first and second jaw members relative to the other from a spaced position to a closer position for manipulating tissue; a handle assembly that includes a fixed handle integrally associated with the housing and a movable handle operably coupled to the drive assembly such that moving the movable handle from a first position to a second position actuates the drive assembly to move the at least one of the first and second jaw members from the spaced position to the closer position; a trigger assembly having a safety position and configured for selectively advancing a knife assembly for cutting tissue between the first and second jaw members characterised in that the trigger assembly includes a safety mechanism that is configured to link the trigger assembly with the movable handle such that, when the movable handle is actuated, the trigger assembly is released and moves from its safety position, whereby the safety mechanism prevents the trigger assembly from firing when the movable handle is oriented in a non-actuated positon. a shaft having a proximal end which is received within the housing, and an end effector assembly disposed at a distal end of the shaft, the end effector assembly including a first jaw member and a second jaw member; a drive assembly operably coupled to the end effector assembly and configured to move at least one of the first and second jaw members relative to the other from a spaced position to a closer position for manipulating tissue; a handle assembly that includes a fixed handle integrally associated with the housing and a movable handle operably coupled to the drive assembly such that moving the movable handle from a first position to a second position actuates the drive assembly to move the at least one of the first and second jaw members from the spaced position to the closer position; a trigger assembly having a safety position and configured for selectively advancing a knife assembly for cutting tissue between the first and second jaw members characterised in that the trigger assembly includes a safety mechanism that is configured to link the trigger assembly with the movable handle such that, when the movable handle is actuated, the trigger assembly is released and moves from its safety position, whereby the safety mechanism prevents the trigger assembly from firing when the movable handle is oriented in a non-actuated positon.
A pneumatic tire, comprising a tread, the tread comprising a rubber composition for tires comprising: a rubber component comprising an isoprene-based rubber and polybutadiene rubber; silica; and a terpene-based resin having a softening point of 60 to 150°C, an α-pinene unit content of 65 to 100% by mass, a β-pinene unit content of 0 to 35% by mass, and a limonene unit content of 10% by mass or lower, the rubber component comprising, based on 100% by mass thereof, 5 to 80% by mass of the isoprene-based rubber and 5 to 80% by mass of the polybutadiene rubber, with a combined amount of the isoprene-based rubber and the polybutadiene rubber of 60% by mass or more, the rubber composition comprising, per 100 parts by mass of the rubber component, 1 to 500 parts by mass of the silica and 0.1 to 100 parts by mass of the terpene-based resin. a rubber component comprising an isoprene-based rubber and polybutadiene rubber; silica; and a terpene-based resin having a softening point of 60 to 150°C, an α-pinene unit content of 65 to 100% by mass, a β-pinene unit content of 0 to 35% by mass, and a limonene unit content of 10% by mass or lower, the rubber component comprising, based on 100% by mass thereof, 5 to 80% by mass of the isoprene-based rubber and 5 to 80% by mass of the polybutadiene rubber, with a combined amount of the isoprene-based rubber and the polybutadiene rubber of 60% by mass or more, the rubber composition comprising, per 100 parts by mass of the rubber component, 1 to 500 parts by mass of the silica and 0.1 to 100 parts by mass of the terpene-based resin.
An ex-vivo method for detecting in a subject a cytotoxic NK cell-mediated immune response or in determining whether a subject has had a therapeutically effective response to the protein conjugate comprising: (a) exposing PBMCs which have been isolated from the subject in vitro to a protein conjugate comprising granulocyte macrophage colony stimulating factor (GM-CSF) covalently linked to a soluble peptide antigen selected from the group consisting of a tumor associated antigen and an oncogene product under conditions effective to activate said PBMCs, wherein said PBMCs are effective in activating NK cells to produce a cytotoxic cellular response that is higher than that produced by the PBMCs which have not been activated by the protein conjugate, which activated PBMCs are to be administered to the subject; (b) repeating step (a) at least 10 days after the activated PBMCs have been administered; and (c) detecting a NK cell response in the activated PBMCs or determining a change in NK cell activity of the activated PBMCs. (a) exposing PBMCs which have been isolated from the subject in vitro to a protein conjugate comprising granulocyte macrophage colony stimulating factor (GM-CSF) covalently linked to a soluble peptide antigen selected from the group consisting of a tumor associated antigen and an oncogene product under conditions effective to activate said PBMCs, wherein said PBMCs are effective in activating NK cells to produce a cytotoxic cellular response that is higher than that produced by the PBMCs which have not been activated by the protein conjugate, which activated PBMCs are to be administered to the subject; (b) repeating step (a) at least 10 days after the activated PBMCs have been administered; and (c) detecting a NK cell response in the activated PBMCs or determining a change in NK cell activity of the activated PBMCs.
A main rotor blade, comprising: a blade root part having a length of 30% or more of a rotor radius; a blade main body continuous with the blade root part, characterised in that a torsion angle of the blade main body has a minimum value (θ min) at a position in a range of 80% to 95% of a rotor radius, and is gradually reduced from a blade root side and from a blade tip side to the position of the minimum value. a blade root part having a length of 30% or more of a rotor radius; a blade main body continuous with the blade root part, characterised in that a torsion angle of the blade main body has a minimum value (θ min) at a position in a range of 80% to 95% of a rotor radius, and is gradually reduced from a blade root side and from a blade tip side to the position of the minimum value.
A container gripper that includes a gripper having a gripping part which is constituted of a pair of gripping pieces disposed to be openable and closable by relative movement, allows a head part of a container to move in and out of the gripper when being opened, and allows the head part to be constrained when being closed, and that alternately changes gripping from a first gripper to a second gripper to deliver the container, the container gripper comprising: an ascending/descending container platform capable of supporting a bottom surface of the container gripped by the gripper, wherein the gripping part of the first gripper includes a first gripping piece that grips at least half of the circumference of a neck part in a gripping shape adapted to the neck part provided at the head part, wherein the gripping part of the second gripper includes a second gripping piece that grips at least half of the circumference of a lower part in conformity with the lower part of the neck part, wherein when a bottle-shaped can is gripped by the second gripping piece, the second gripping piece grips the lower part of the neck part, and a bottom surface of the bottle-shaped can is supported by the container platform, characterised in that when a PET bottle is gripped by the second gripping piece, the second gripping piece comes into contact with an underside of a neck ring of the PET bottle, and grips a lower part of a neck part, and the container platform is withdrawn to a position where the container platform does not come into contact with a bottom surface of the PET bottle, and wherein the container gripper is configured to be capable of being used to hold both the bottle-shaped can and the PET bottle. an ascending/descending container platform capable of supporting a bottom surface of the container gripped by the gripper, wherein the gripping part of the first gripper includes a first gripping piece that grips at least half of the circumference of a neck part in a gripping shape adapted to the neck part provided at the head part, wherein the gripping part of the second gripper includes a second gripping piece that grips at least half of the circumference of a lower part in conformity with the lower part of the neck part, wherein when a bottle-shaped can is gripped by the second gripping piece, the second gripping piece grips the lower part of the neck part, and a bottom surface of the bottle-shaped can is supported by the container platform, characterised in that when a PET bottle is gripped by the second gripping piece, the second gripping piece comes into contact with an underside of a neck ring of the PET bottle, and grips a lower part of a neck part, and the container platform is withdrawn to a position where the container platform does not come into contact with a bottom surface of the PET bottle, and wherein the container gripper is configured to be capable of being used to hold both the bottle-shaped can and the PET bottle.
A tire (400, 500), comprising: a first surface (103, 303, 403, 503, 603, 703, 803, 903); a second surface (401, 501); and a tire body (102, 302, 402, 502, 602, 702, 802, 902) contained between the first surface (103, 303, 403, 503, 603, 703, 803, 903) and the second surface (401, 501); wherein the tire body (102, 302, 402, 502, 602, 702, 802, 902) comprises a cavity having a cavity major width in at least one of an axial direction and a circumferential direction, wherein a channel extends between the cavity and the first surface (103, 303, 403, 503, 603, 703, 803, 903), wherein the channel has a channel major width in at least one of the axial direction and the circumferential direction, and wherein the cavity major width is greater than the channel major width, characterized by a fastener (210, 310, 410, 510, 610, 710, 810, 910) including a fastener portion (212, 312, 412, 512, 612, 712, 812, 912) and a protrusion (214, 314, 414, 514, 614, 714, 814, 914) oriented adjacent to the fastener portion (212, 312, 412, 5 12, 612, 712, 812, 912); wherein the fastener portion (212, 312, 412, 512, 612, 712, 812, 912) is configured to at least one of removably attach to a device (417, 517, 617, 717, 817, 917) and permanently attach to a device (417, 517, 617, 717, 817, 917), wherein the fastener portion (212, 312, 412, 512, 612, 712, 812, 912) extends through an aperture in the device (417, 517, 617, 717, 817, 917), and wherein the protrusion (214, 314, 414, 514, 614, 714, 814, 914) is engaged within the cavity. a first surface (103, 303, 403, 503, 603, 703, 803, 903); a second surface (401, 501); and a tire body (102, 302, 402, 502, 602, 702, 802, 902) contained between the first surface (103, 303, 403, 503, 603, 703, 803, 903) and the second surface (401, 501); wherein the tire body (102, 302, 402, 502, 602, 702, 802, 902) comprises a cavity having a cavity major width in at least one of an axial direction and a circumferential direction, wherein a channel extends between the cavity and the first surface (103, 303, 403, 503, 603, 703, 803, 903), wherein the channel has a channel major width in at least one of the axial direction and the circumferential direction, and wherein the cavity major width is greater than the channel major width, characterized by a fastener (210, 310, 410, 510, 610, 710, 810, 910) including a fastener portion (212, 312, 412, 512, 612, 712, 812, 912) and a protrusion (214, 314, 414, 514, 614, 714, 814, 914) oriented adjacent to the fastener portion (212, 312, 412, 5 12, 612, 712, 812, 912); wherein the fastener portion (212, 312, 412, 512, 612, 712, 812, 912) is configured to at least one of removably attach to a device (417, 517, 617, 717, 817, 917) and permanently attach to a device (417, 517, 617, 717, 817, 917), wherein the fastener portion (212, 312, 412, 512, 612, 712, 812, 912) extends through an aperture in the device (417, 517, 617, 717, 817, 917), and wherein the protrusion (214, 314, 414, 514, 614, 714, 814, 914) is engaged within the cavity.