mhurhangee/ep-ind-claims huggingface dataset:
A method for identifying a gene cluster capable of producing a secondary metabolite for modulating a target protein, the method comprising: selecting, from a database comprising a list of biosynthetic gene clusters, one or more gene clusters that include or are positioned proximal to a region that encodes a protein that is identical with or homologous to the target protein, expressing the gene cluster or a plurality of genes from the gene cluster in a host cell; isolating a secondary metabolite produced by the gene cluster or the plurality of genes from the gene cluster; and screening the isolated secondary metabolite for modulation of an activity of the target protein thereby identifying the gene cluster; wherein the one or more gene clusters are selected from the group consisting of clusters that comprise one or more polyketide synthases and clusters that comprise one or more non-ribosomal peptide synthetases, clusters that comprise one or more terpene synthases, clusters that comprises one or more UbiA-type terpene cyclases, and clusters that comprise one or more dimethylallyl transferases. selecting, from a database comprising a list of biosynthetic gene clusters, one or more gene clusters that include or are positioned proximal to a region that encodes a protein that is identical with or homologous to the target protein, expressing the gene cluster or a plurality of genes from the gene cluster in a host cell; isolating a secondary metabolite produced by the gene cluster or the plurality of genes from the gene cluster; and screening the isolated secondary metabolite for modulation of an activity of the target protein thereby identifying the gene cluster; wherein the one or more gene clusters are selected from the group consisting of clusters that comprise one or more polyketide synthases and clusters that comprise one or more non-ribosomal peptide synthetases, clusters that comprise one or more terpene synthases, clusters that comprises one or more UbiA-type terpene cyclases, and clusters that comprise one or more dimethylallyl transferases.
A transition metal compound represented by the following Formula 1a: in Formula 1a, M is Ti, Zr or Hf, R 5 and R 6 are each independently hydrogen; a substituted or unsubstituted alkyl group of 1 to 20 carbon atoms; a substituted or unsubstituted cycloalkyl group of 3 to 20 carbon atoms; or a substituted or unsubstituted aryl group of 6 to 20 carbon atoms, where the substitution is conducted with an alkyl group of 1 to 12 carbon atoms, each R 7 is independently a cycloalkyl group of 4 to 20 carbon atoms; or an aryl group of 6 to 20 carbon atoms, and Y 1 and Y 2 are each independently a halogen group; an alkyl group of 1 to 20 carbon atoms; an alkenyl group of 2 to 20 carbon atoms; an alkynyl group or 2 to 20 carbon atoms; a cycloalkyl group of 3 to 20 carbon atoms; an aryl group of 6 to 20 carbon atoms; an alkylaryl group of 7 to 20 carbon atoms; an arylalkyl group of 7 to 20 carbon atoms; a heteroaryl group of 5 to 20 carbon atoms; an alkoxy group of 1 to 20 carbon atoms; an aryloxy group of 6 to 20 carbon atoms; an alkylamino group of 1 to 20 carbon atoms; an arylamino group of 5 to 20 carbon atoms; an alkylthio group of 1 to 20 carbon atoms; an arylthio group of 5 to 20 carbon atoms; an alkylsilyl group of 1 to 20 carbon atoms; an arylsilyl group of 5 to 20 carbon atoms; a hydroxyl group; an amino group; a thio group; a silyl group; a cyano group; or a nitro group. M is Ti, Zr or Hf, R 5 and R 6 are each independently hydrogen; a substituted or unsubstituted alkyl group of 1 to 20 carbon atoms; a substituted or unsubstituted cycloalkyl group of 3 to 20 carbon atoms; or a substituted or unsubstituted aryl group of 6 to 20 carbon atoms, where the substitution is conducted with an alkyl group of 1 to 12 carbon atoms, each R 7 is independently a cycloalkyl group of 4 to 20 carbon atoms; or an aryl group of 6 to 20 carbon atoms, and Y 1 and Y 2 are each independently a halogen group; an alkyl group of 1 to 20 carbon atoms; an alkenyl group of 2 to 20 carbon atoms; an alkynyl group or 2 to 20 carbon atoms; a cycloalkyl group of 3 to 20 carbon atoms; an aryl group of 6 to 20 carbon atoms; an alkylaryl group of 7 to 20 carbon atoms; an arylalkyl group of 7 to 20 carbon atoms; a heteroaryl group of 5 to 20 carbon atoms; an alkoxy group of 1 to 20 carbon atoms; an aryloxy group of 6 to 20 carbon atoms; an alkylamino group of 1 to 20 carbon atoms; an arylamino group of 5 to 20 carbon atoms; an alkylthio group of 1 to 20 carbon atoms; an arylthio group of 5 to 20 carbon atoms; an alkylsilyl group of 1 to 20 carbon atoms; an arylsilyl group of 5 to 20 carbon atoms; a hydroxyl group; an amino group; a thio group; a silyl group; a cyano group; or a nitro group.
A method, executable on one or more processors, for noise estimation with music detection, the method characterized by: generating a music classification for music content in an audio signal and a voice classification for voice content in an audio signal, where the generated music classification comprises a value selected from a range of values, the value indicating a proportion of an amount of music content and an amount of non-music content; adjusting an adaption rate responsive to the generated music classification and the generated voice classification; and calculating a noise estimate applying the adjusted adaption rate; wherein adjusting the adaption rate comprises a proportional adjustment to the adaption rate responsive to changes of the generated music classification. generating a music classification for music content in an audio signal and a voice classification for voice content in an audio signal, where the generated music classification comprises a value selected from a range of values, the value indicating a proportion of an amount of music content and an amount of non-music content; adjusting an adaption rate responsive to the generated music classification and the generated voice classification; and calculating a noise estimate applying the adjusted adaption rate; wherein adjusting the adaption rate comprises a proportional adjustment to the adaption rate responsive to changes of the generated music classification.
Salt of bis(fluorosulfonyl)imide containing from 0.01 ppm in weight to 10000 ppm in weight in weight of a halogenated alcohol, wherein it is represented by the formula: [ (FSO 2) 2 N -] n M n+ wherein M n+ represents the ammonium cation NH 4 + or an alkali metal cation, and n is 1 representing the valence of the cation M, and wherein said salt of bis(fluorosulfonyl)imide is in the form of a solid crystallized compound.
A mammary prosthesis for implantation in a human being, the prosthesis comprising: an implantable member (20; 30; 40; 60; 70; 110) including an exterior surface defined by an anterior face and a posterior face (22; 62; 72); the anterior face includes at least one generally elongated fixation region defined by a texture, roughness or sheen different from a respective texture, roughness or sheen of a balance of said one of the anterior face and posterior face; characterized in that the at least one elongated fixation region comprises a band-shaped fixation region (66; 114) or discrete fixation regions (76a, 76b, 76c); the prosthesis being structured such that when implanted adjacent a muscle group of the pectoralis major muscle groups and the pectoralis minor muscle groups in a human being, the fixation region can be generally aligned with an alignment of said muscle group. an implantable member (20; 30; 40; 60; 70; 110) including an exterior surface defined by an anterior face and a posterior face (22; 62; 72); the anterior face includes at least one generally elongated fixation region defined by a texture, roughness or sheen different from a respective texture, roughness or sheen of a balance of said one of the anterior face and posterior face; characterized in that the at least one elongated fixation region comprises a band-shaped fixation region (66; 114) or discrete fixation regions (76a, 76b, 76c); the prosthesis being structured such that when implanted adjacent a muscle group of the pectoralis major muscle groups and the pectoralis minor muscle groups in a human being, the fixation region can be generally aligned with an alignment of said muscle group.
Drawing device for feeding at least two metal products such as bars, round pieces or wire, to a working machine such as a bending machine, stirrup-making machine or shaping machine, comprising at least a first drawing unit suitable to move at least a first metal product on a first feed plane defining a first advance axis, and a second drawing unit (14; 114), different from the first and disposed aligned upstream or downstream of said first drawing unit, and suitable to move a second metal product on a second feed plane and defining a second advance axis, substantially parallel to the first advance axis, characterized in that said first drawing unit comprises at least a pair of drawing rolls (21, 23), at least one of which being motorized, with which is associated a corresponding pair of guide rolls (45, 47) of the second drawing unit (14; 114), and said second drawing unit (14; 114) comprises at least a pair of drawing rolls (46, 48), at least one of which being motorized, with which is associated a corresponding pair of guide rolls (22, 24) of the first drawing unit, and in that a pair of drawing rolls (21, 23) of the first drawing unit is aligned with a pair of guide rolls (45, 47) of the second drawing unit (14; 114) on the first feed plane, and a pair of guide rolls (22, 24) of the first drawing unit is aligned with a pair of drawing rolls (46, 48) of the second drawing unit (14; 114) on the second feed plane.
An intradermal delivery system comprising a solid biodegradable microneedle, wherein the microneedle comprises a benzonaphthyridine TLR7 agonist and an immunogen,, wherein the immunogen is a bacterial antigen.
Stud setting tool for setting fasteners in place in a substrate, having a working piston which, by the ignition of an ignitable mixture in a combustion chamber, can be moved percussively in translation in order to set in place a fastener such as a stud or a nail, the volume of the combustion chamber being adjustable, characterised in that the stud setting tool comprises a control means which is connected in a controlling capacity to an adjusting means for adjusting the combustion chamber volume and to a metering valve means for metering combustible gas.
A superabsorbent polymer, characterized by: a plurality of polymeric particles and each the polymeric particles having an internally cross-linked structure; a surface cross-linking agent bonded to a surface of each the polymeric particles so as to constitute a layer of surface cross-linked region at the surface of each the polymeric particle, wherein the degree of cross-linking of the surface cross-linked region is higher than the degree of cross-linking of the polymeric particles to form a core-shell structure; and an extract of Sapindaceae covering the entire surface of the surface cross-linked region on each the polymeric particles, the extract of Sapindaceae having a concentration between 10 and 1000 ppm relative to the superabsorbent polymeric particles; and wherein the extract of Sapindaceae is represented by the following formula: a plurality of polymeric particles and each the polymeric particles having an internally cross-linked structure; a surface cross-linking agent bonded to a surface of each the polymeric particles so as to constitute a layer of surface cross-linked region at the surface of each the polymeric particle, wherein the degree of cross-linking of the surface cross-linked region is higher than the degree of cross-linking of the polymeric particles to form a core-shell structure; and an extract of Sapindaceae covering the entire surface of the surface cross-linked region on each the polymeric particles, the extract of Sapindaceae having a concentration between 10 and 1000 ppm relative to the superabsorbent polymeric particles; and wherein the extract of Sapindaceae is represented by the following formula:
A method of data transfer using an examination device for producing electrical data from an organ, the method comprising the steps of: receiving an identifier determining the examination device by an auxiliary server, which has installation data associated with the identifier; transmitting the installation data associated with the examination device identifier from the auxiliary server to a server of a patient data system; automatically installing the identifier determining the examination device on the basis of the installation data on the server of the patient data system for data transfer; characterized by detecting, by the examination device, the patient data system to be used; and transferring data between the examination device and the server of the patient data system on the basis of Digital Imaging and Communications in Medicine (DICOM) or Health Level 7 after installing the identifier. receiving an identifier determining the examination device by an auxiliary server, which has installation data associated with the identifier; transmitting the installation data associated with the examination device identifier from the auxiliary server to a server of a patient data system; automatically installing the identifier determining the examination device on the basis of the installation data on the server of the patient data system for data transfer; characterized by detecting, by the examination device, the patient data system to be used; and transferring data between the examination device and the server of the patient data system on the basis of Digital Imaging and Communications in Medicine (DICOM) or Health Level 7 after installing the identifier.
An electric storage apparatus comprising a plurality of electric storage elements connected electrically in series, and when the plurality of electric storage elements are divided into a plurality of blocks, the electric storage apparatus includes a reused first block (12,A), characterized in that the reused first block (12,A) has a resistance increase rate lower than a resistance increase rate of a second block (12,B-D).
An absorbent tampon comprising a mass of absorbent material which has been compressed primarily in the width direction into a generally cylindrical, self-sustaining form, wherein subsequent to compression the generally cylindrical, self-sustaining form comprises a maximum transverse dimension of less than 13 millimeters, wherein the tampon has a syngyna absorbent capacity of between 6 and 9 grams, and wherein the tampon undergoes a growth, upon fluid absorption, in transverse dimension of at least 13 millimeters in the absence of a contained pressure, wherein the mass of absorbent material comprises 100% of rayon and wherein the generally cylindrical, self-sustaining form has a density of greater than 0.35 grams per cubic centimeter.
An apparatus that is secure from unauthorized use, comprising: a component; an explosive positioned such that, when the explosive is ignited, an explosive charge from the explosive will destroy the component; a processor adapted to generate a signal for igniting the explosive when at least one predetermined event occurs, characterised in the apparatus further comprising: a metallic material positioned between the explosive and the component, wherein a composition, size and position of the metallic material is such that the explosive charge will melt the metallic material onto the component. a component; an explosive positioned such that, when the explosive is ignited, an explosive charge from the explosive will destroy the component; a processor adapted to generate a signal for igniting the explosive when at least one predetermined event occurs, characterised in the apparatus further comprising: a metallic material positioned between the explosive and the component, wherein a composition, size and position of the metallic material is such that the explosive charge will melt the metallic material onto the component.
A method for producing a plated part, comprising: (a) applying a catalyst inactivator to a surface of a base member, the catalyst inactivator directly reacting with an electroless plating catalyst to prevent the electroless plating catalyst from exerting catalytic ability; (b) irradiating with light or heating a part of the surface of the base member to which the catalyst inactivator is applied, the light being a laser beam; (c) applying the electroless plating catalyst to the surface of the base member by bringing a catalyst solution in which the electroless plating catalyst is dissolved into contact with the surface of the base member, thereby bringing the electroless plating catalyst dissolved in the catalyst solution into contact with the catalyst inactivator; and (d) bringing an electroless plating solution into contact with the surface of the base member retaining the electroless plating catalyst to form an electroless plating film at a light-irradiated portion or a heated portion of the surface, wherein the steps (a) to (d) are performed in order. (a) applying a catalyst inactivator to a surface of a base member, the catalyst inactivator directly reacting with an electroless plating catalyst to prevent the electroless plating catalyst from exerting catalytic ability; (b) irradiating with light or heating a part of the surface of the base member to which the catalyst inactivator is applied, the light being a laser beam; (c) applying the electroless plating catalyst to the surface of the base member by bringing a catalyst solution in which the electroless plating catalyst is dissolved into contact with the surface of the base member, thereby bringing the electroless plating catalyst dissolved in the catalyst solution into contact with the catalyst inactivator; and (d) bringing an electroless plating solution into contact with the surface of the base member retaining the electroless plating catalyst to form an electroless plating film at a light-irradiated portion or a heated portion of the surface,
A method for a terminal to provide image painting information, the method comprising: displaying a paintable first image on a screen of the terminal; receiving a user input for selecting a partial region of the first image; in response to the partial region being included in a first boundary region of the first image, which is located within a predetermined distance from a division line between the first image and a second image, requesting painting information of a second boundary region of the second image, which is located within a predetermined distance from the division line, from a server separated from the terminal; receiving the requested painting information from the server; and displaying the received painting information of the second boundary region of the second image along with the first image on the screen of the terminal, wherein the first image and the second image are divided from a single image based on the division line. displaying a paintable first image on a screen of the terminal; receiving a user input for selecting a partial region of the first image; in response to the partial region being included in a first boundary region of the first image, which is located within a predetermined distance from a division line between the first image and a second image, requesting painting information of a second boundary region of the second image, which is located within a predetermined distance from the division line, from a server separated from the terminal; receiving the requested painting information from the server; and displaying the received painting information of the second boundary region of the second image along with the first image on the screen of the terminal, wherein the first image and the second image are divided from a single image based on the division line.
A method of secure and computationally efficient estimation of a number of members in a multiset having attributes that satisfy target criteria, comprising: receiving, by an aggregator computing device comprising one or more processors and a memory, an encrypted data structure from a worker computing device; constructing, by the aggregator computing device, a histogram data structure using the encrypted data structure; estimating, by the aggregator computing device and using the histogram data structure, a frequency value representing a number of device identifiers associated with an attribute that satisfies a target criteria; and transmitting, by the aggregator computing device, the frequency value to a publisher computing device. receiving, by an aggregator computing device comprising one or more processors and a memory, an encrypted data structure from a worker computing device; constructing, by the aggregator computing device, a histogram data structure using the encrypted data structure; estimating, by the aggregator computing device and using the histogram data structure, a frequency value representing a number of device identifiers associated with an attribute that satisfies a target criteria; and transmitting, by the aggregator computing device, the frequency value to a publisher computing device.
Purified therapeutic nanoparticles, comprising paclitaxel and human serum albumin, wherein the weight ratio of human serum albumin to paclitaxel in the therapeutic nanoparticles is selected from 0.03:1, 0.04:1, 0.05:1, 0.06:1, 0.07:1, 0.08:1, 0.09:1, 0.10:1, 0.11:1, 0.12:1, 0.13:1, 0.14:1, 0.15:1, 0.16:1, 0.17:1, 0.18:1, 0.19:1, 0.2:1, 0.21:1, 0.22:1, 0.23:1, 0.24:1, 0.25:1, 0.26:1, 0.27:1, 0.28:1, 0.29:1, 0.3:1, 0.31:1, 0.32:1, 0.33:1, 0.34:1, 0.35:1, 0.36:1, 0.37:1, 0.38:1, 0.39:1, 0.4:1, 0.41:1, 0.42:1, 0.43:1, 0.44:1, 0.45:1, 0.46:1, 0.47:1, 0.48:1, 0.49:1, 0.5:1, 0.51:1, 0.52:1, 0.53:1, 0.54:1, 0.55:1, 0.56:1, 0.57:1, 0.58:1, 0.59:1, 0.6:1, 0.65:1, 0.70:1, 0.75:1, 0.8:1, 0.85:1, 0.9:1, 0.95:1 or the range between any two ratios above, wherein the nanoparticles contain less than 10% free HSA (by weight).
A method for visual inspection of a photovoltaic module, wherein the photovoltaic module comprises a plurality of sets of solar cell strings and a plurality of film strips, the sets of solar cell strings each comprise a plurality of solar cells, the film strips are arranged opposite to cell gaps formed between the solar cells or string gaps formed between the solar cell strings, and lengths of the film strips are less than lengths of the cell gaps or the string gaps, the method comprises: turning on a first light source located above the photovoltaic module, and recording, by an image collector, first coordinates and second coordinates of edge intersections at ends of the film strips; turning on a second light source located below the photovoltaic module, and recording, by the image collector, third coordinates and fourth coordinates of overlapping points among edges of the solar cells, the ends of the film strips, and the cell gaps or the string gaps; and analyzing, by the image collector, differences between the first coordinates and the third coordinates and between the second coordinates and the fourth coordinates along width directions of the cell gaps or the string gaps, wherein the differences are overlap spacings between the film strips and the solar cells.
A method of binding a plurality of pages comprising: window-cutting a slit on each page of the plurality of pages; punching holes on each page of a plurality of pages at a predetermined interval in a manner such that for the first half of the plurality of pages the holes are punched with a regular reducing distance from a spine and for the second half of the plurality of the pages the holes are punched at a regular increasing distance from the spine resulting in a V-shaped spine, wherein the holes are located on space between the spine and the slit; and wherein the V-shape is obtained by aligning the holes of the plurality of pages; and stapling the plurality of pages in a manner such that a book is obtained with a flat layout.