mhurhangee/ep-ind-claims huggingface dataset:
A method for obtaining epigenetic information for a biological sample obtained from a human, animal or plant subject, the method including the step of: analyzing the biological sample, the sample containing a substantially isolated DNA molecule, by: determining the presence or absence of two or more methylated bases in the DNA molecule, wherein the presence or absence of the methylated bases is capable of modulating expression of the DNA molecule in vivo; and determining whether any two methylated bases are present in cis on the DNA molecule; characterised in that the substantially isolated DNA molecule is isolated using a physical method; and wherein the substantially isolated DNA molecule consists of a single chromosome or a chromatid, or a fragment thereof. analyzing the biological sample, the sample containing a substantially isolated DNA molecule, by: determining the presence or absence of two or more methylated bases in the DNA molecule, wherein the presence or absence of the methylated bases is capable of modulating expression of the DNA molecule in vivo; and determining whether any two methylated bases are present in cis on the DNA molecule; characterised in that the substantially isolated DNA molecule is isolated using a physical method; and wherein the substantially isolated DNA molecule consists of a single chromosome or a chromatid, or a fragment thereof. determining the presence or absence of two or more methylated bases in the DNA molecule, wherein the presence or absence of the methylated bases is capable of modulating expression of the DNA molecule in vivo; and determining whether any two methylated bases are present in cis on the DNA molecule; characterised in that the substantially isolated DNA molecule is isolated using a physical method; and wherein the substantially isolated DNA molecule consists of a single chromosome or a chromatid, or a fragment thereof.
A process for preparing a polysaccharide derivative, comprising the steps of: (a) contacting at least one polysaccharide excluding cyclodextrin and heparin with at least one non isocyanate reactive polysaccharide swelling agent in an amount of at least 25% by weight based on the total weight of the polysaccharide and the swelling agent combined, essentially in the absence of water, at a temperature of from 15 to 35°C; and (b) subsequently, contacting the product of step (a) with at least one aromatic polyisocyanate; thereby preparing a polysaccharide derivative.
Comminution device, comprising a cylinder surrounding a comminution chamber, in which several rotors (30, 32, 34) are driven independently from each other by their own drives, which rotors are driven via concentric shafts (14, 16, 18) which are arranged concentrically to the central axis (z) of the comminution chamber, which concentric shafts comprise a central shaft as well as at least one outer hollow shaft (16, 18) surrounding the central shaft, whereby in the central shaft and/or in a shaft sheath at least one lubricant pipe to be connected with a lubricant supply is arranged, which lubricant pipe is connected with at least one bearing (22, 26, 28) of the rotors via a radial lubricant conduct, characterized in that at least one shaft (14, 16, 18) comprises in the area of its lubricant conduct a radial extending lubricant channel which abuts to the wall of an adjacent shaft in the area of a lubricant conduct located therein.
A method for dielectrically insulating an electrical active part wherein the electrical active part is arranged in a gas-tight housing comprising an insulating medium consisting of, consisting essentially of, or comprising a compound of general formula: SF (6-n) n wherein n is 1, 2, 3, 4, or 5; and R is alkyl, alkenyl, alkynyl, aryl, fluorosubstituted alkyl, fluorosubstituted alkenyl, fluorosubstituted alkynyl or fluorosubstituted aryl.
A photocurable resin composition comprising ingredient: a polymer having a polyisobutylene backbone represented by a general formula: wherein R 1 represents a monovalent or polyvalent aromatic hydrocarbon group or a monovalent or polyvalent aliphatic hydrocarbon group, PIB represents the polyisobutylene backbone containing the - [CH 2 C (CH 3) 2] - unit, R 2 and R 3 each independently represent a hydrogen atom or a monovalent hydrocarbon group having 1 to 20 carbon atoms, R 4 represents a divalent hydrocarbon group having 2 to 6 carbon atoms and optionally containing an oxygen atom, R 5 represents a hydrogen atom, a methyl group, an ethyl group, or a propyl group, and n is any integer of 1 to 6;, characterized in that the photocurable resin composition further comprises: ingredient: a photo-radical initiator of hydrogen abstraction type; and ingredient: a (meth)acrylate monomer containing an alkyl group having 5 to 30 carbon atoms or an alicyclic group having 5 to 30 carbon atoms. ingredient: a polymer having a polyisobutylene backbone represented by a general formula: wherein R 1 represents a monovalent or polyvalent aromatic hydrocarbon group or a monovalent or polyvalent aliphatic hydrocarbon group, PIB represents the polyisobutylene backbone containing the - [CH 2 C (CH 3) 2] - unit, R 2 and R 3 each independently represent a hydrogen atom or a monovalent hydrocarbon group having 1 to 20 carbon atoms, R 4 represents a divalent hydrocarbon group having 2 to 6 carbon atoms and optionally containing an oxygen atom, R 5 represents a hydrogen atom, a methyl group, an ethyl group, or a propyl group, and n is any integer of 1 to 6;, characterized in that the photocurable resin composition further comprises: ingredient: a photo-radical initiator of hydrogen abstraction type; and ingredient: a (meth)acrylate monomer containing an alkyl group having 5 to 30 carbon atoms or an alicyclic group having 5 to 30 carbon atoms.
A surface treatment method for treating a surface of a single crystal SiC substrate, in which the single crystal SiC substrate is etched by performing a heat treatment under Si vapor pressure, the method including an etching step of controlling the rate of etching by adjusting inert gas pressure of an atmosphere around the single crystal SiC substrate, wherein the single crystal SiC substrate has an off angle relative to a face, in the etching step, the heat treatment is performed on the single crystal SiC substrate in an atmosphere of an inert gas and Si, to remove macro-step bunching formed during the treatment performed on the surface of the single crystal SiC substrate, wherein the inert gas pressure at a time of removal of the macro-step bunching is, at least temporarily, 10 Pa or less, wherein (i) the single crystal SiC substrate is heated to a temperature of 1000°C or more and 2300°C or less and/or (ii) the inert gas is Argon gas. the method including an etching step of controlling the rate of etching by adjusting inert gas pressure of an atmosphere around the single crystal SiC substrate, wherein the single crystal SiC substrate has an off angle relative to a face, in the etching step, the heat treatment is performed on the single crystal SiC substrate in an atmosphere of an inert gas and Si, to remove macro-step bunching formed during the treatment performed on the surface of the single crystal SiC substrate, wherein the inert gas pressure at a time of removal of the macro-step bunching is, at least temporarily, 10 Pa or less, wherein (i) the single crystal SiC substrate is heated to a temperature of 1000°C or more and 2300°C or less and/or (ii) the inert gas is Argon gas.
Method for molding a mold by compressing foundry sand disposed in a molding space defined by a pattern plate (5, 31), a flask-shaped flask-removing frame or a lower subsidiary flask disposed around said pattern plate (5, 31) so as to be movable up and down and a molding flask (20, 33) disposed above the flask-shaped flask-removing frame or lower subsidiary flask, the method comprising: a step for throwing foundry sand into the molding space, and a first step for pressing down the foundry sand in the molding space while at least said flask-shaped removing frame or lower subsidiary flask is being kept unable to go downward, and a second step for pressing down the foundry sand in the molding space while both said flask-shaped removing frame or lower subsidiary flask and the molding flask (20, 33) are being kept able to go downward. a step for throwing foundry sand into the molding space, and a first step for pressing down the foundry sand in the molding space while at least said flask-shaped removing frame or lower subsidiary flask is being kept unable to go downward, and a second step for pressing down the foundry sand in the molding space while both said flask-shaped removing frame or lower subsidiary flask and the molding flask (20, 33) are being kept able to go downward.
A semiconductor device comprising: a substrate having opposed first and second major surfaces, an active area, and a termination area surrounding the active area; insulated trenches extending from the first major surface toward the second major surface, and having a longitudinal direction, each of the insulated trenches including a conductive field plate and a gate electrode overlying the conductive field plate, the gate electrode being separated from the field plate by a gate-field plate insulator, wherein the conductive field plate extends longitudinally in both of the active and termination areas and the gate electrode extends longitudinally in the active area and is absent in the termination area; and a body region of a first conductivity type extending laterally between pairs of the insulated trenches; characterised by first and second (112 2) spacer regions of a second conductivity type extending laterally between the pairs of the insulated trenches and perpendicularly to the longitudinal direction thereof, at the termination area defined by segments of the first conductivity type, between the first and second spacer regions and that are isolated from the body region. a substrate having opposed first and second major surfaces, an active area, and a termination area surrounding the active area; insulated trenches extending from the first major surface toward the second major surface, and having a longitudinal direction, each of the insulated trenches including a conductive field plate and a gate electrode overlying the conductive field plate, the gate electrode being separated from the field plate by a gate-field plate insulator, wherein the conductive field plate extends longitudinally in both of the active and termination areas and the gate electrode extends longitudinally in the active area and is absent in the termination area; and a body region of a first conductivity type extending laterally between pairs of the insulated trenches; characterised by first and second (112 2) spacer regions of a second conductivity type extending laterally between the pairs of the insulated trenches and perpendicularly to the longitudinal direction thereof, at the termination area defined by segments of the first conductivity type, between the first and second spacer regions and that are isolated from the body region.
An abrasive tool, including on the work face more than two abrasive elements with different roughness (50, 64, 78, 86, 96, 104, 114, 140, 170, 180, 210, 218, 230, 262, 271) arranged in a manner so as to form, along at least one path between adjacent abrasive elements, a sequence that is ordered by increasing or decreasing roughness values, the abrasive tool having circular shape or any one regular polygonal shape (50. 64, 78, 86, 96, 104, 114, 140, 170, 180), the arrangement of said abrasive elements involving a distribution of abrasive mass with respect to the centre of the tool such that the abrasive elements m1, m2 whose centres of mass are aligned on opposite sides with respect to the centre of the tool, respectively at distances r1, r2 therefrom, generate equivalent contributions m1.r12 and m2.r22 to the moment of inertia of the tool, characterized in that the distance of each abrasive element from the centre of the tool increases or decreases from one abrasive element to the adjacent one, depending on the clockwise or counter-clockwise direction said at least one sequence is followed.
A method of actuating a hydraulically operated device comprising: exhausting, in response to a demand to actuate a hydraulically operated device, a first volume of pressurized hydraulic fluid through a discharge port of a pressure supply device in response to igniting a first gas generator of two or more gas generators, wherein the pressure supply device comprises: an elongated body having an internal bore extending from a power end to a discharge end having the discharge port, the two or more gas generators connected to the power end, and hydraulic fluid disposed in the internal bore between a piston and the discharge end; and exhausting, in response to a demand to actuating the hydraulically operated device, a second volume of pressurized hydraulic fluid through the discharge port in response to igniting a second gas generator of the two or more gas generators; actuating the hydraulically operated device to a first position in response to the hydraulically operated device receiving the first volume of pressurized hydraulic fluid; and actuating the hydraulically operated device to a second position in response to the hydraulically operated device receiving the second volume of pressurized hydraulic fluid. exhausting, in response to a demand to actuate a hydraulically operated device, a first volume of pressurized hydraulic fluid through a discharge port of a pressure supply device in response to igniting a first gas generator of two or more gas generators, wherein the pressure supply device comprises: an elongated body having an internal bore extending from a power end to a discharge end having the discharge port, the two or more gas generators connected to the power end, and hydraulic fluid disposed in the internal bore between a piston and the discharge end; and exhausting, in response to a demand to actuating the hydraulically operated device, a second volume of pressurized hydraulic fluid through the discharge port in response to igniting a second gas generator of the two or more gas generators; actuating the hydraulically operated device to a first position in response to the hydraulically operated device receiving the first volume of pressurized hydraulic fluid; and actuating the hydraulically operated device to a second position in response to the hydraulically operated device receiving the second volume of pressurized hydraulic fluid.
Method of adaptive laser joining of stator and rotor laminations, wherein laser joining of individual laminations only takes place where two adjacent laminations come into contact, wherein it comprises: - detecting an individual gap between laminations by means of a sensor in real time; - based on the signal from the sensor, triggering an individual laser pulse, or - based on the signal from the sensor, performing a software-driven modulation of the signal with parameters defined beforehand, and controlling the continuous laser beam by means of the modulated signal; - wherein the detection of an individual gap by means of the sensor in real time comprises adjusting the detection range of the sensor, transmitting the signal from the sensor through a filter, said filter being used for removal of the noise from the signal of the sensor, to a microcontroller in a control unit, which transforms the analog signal to digital under certain conditions, defined beforehand and obtained by testing various thicknesses of the individual laminas, sending the digital signal to a microcontroller, which delays the original signal in order to allow for the correct positioning of the sensor relative to the gap in the workpiece; - the triggering of the individual laser pulses and the controlling of the continuous laser beam, respectively, being controlled by means of the microcontroller in the control unit. - detecting an individual gap between laminations by means of a sensor in real time; - based on the signal from the sensor, triggering an individual laser pulse, or - based on the signal from the sensor, performing a software-driven modulation of the signal with parameters defined beforehand, and controlling the continuous laser beam by means of the modulated signal; - wherein the detection of an individual gap by means of the sensor in real time comprises adjusting the detection range of the sensor, transmitting the signal from the sensor through a filter, said filter being used for removal of the noise from the signal of the sensor, to a microcontroller in a control unit, which transforms the analog signal to digital under certain conditions, defined beforehand and obtained by testing various thicknesses of the individual laminas, sending the digital signal to a microcontroller, which delays the original signal in order to allow for the correct positioning of the sensor relative to the gap in the workpiece; - the triggering of the individual laser pulses and the controlling of the continuous laser beam, respectively, being controlled by means of the microcontroller in the control unit.
Method of producing intumescent plastic moulded parts consisting of a reaction plastic containing intumescent additives and glass fibres, the method comprising the following steps: - providing an additive mixture consisting of the intumescent additives and the glass fibres, - mixing the additive mixture and the reactive components of the plastic, thereby resulting in a homogeneous composition, - introducing the composition consisting of the components of the plastic and the additive mixture into an injection mould and - curing and foaming the composition in the mould, wherein the intumescent additives are present in pulverulent form and the glass fibres are broken down in the intumescent additives, and wherein the intumescent additives are fluidised prior to the introduction of the glass fibres so that the intumescent additives have liquid or pasty properties, and wherein a high-speed stirrer is used for the fluidising process. - providing an additive mixture consisting of the intumescent additives and the glass fibres, - mixing the additive mixture and the reactive components of the plastic, thereby resulting in a homogeneous composition, - introducing the composition consisting of the components of the plastic and the additive mixture into an injection mould and - curing and foaming the composition in the mould,
Laminated safety glass of the type comprising: - two or more sheets or panes of glass or crystal (5, 6) superimposed one on the other, and - a plurality of little plates or studs that are provided for fastening the laminated glass to an external support structure and are each stably housed in a respective hole or seat formed in said laminated glass, wherein said holes or seats, in which said plates or studs are stably housed, are provided and formed only in one or first of the two or more sheets or panes of glass or crystal (5, 6) of which said laminated safety glass is composed, whereby the other or second sheet or pane adjacent to the first pane remains completely intact and without any type of working on its surface also in the zone of such holes or seats, wherein an upper portion of each of said plates or studs protrudes from the respective hole or seat of the first pane, thereby forming a relief adapted to create a contrast plain surface, distinct and separate from the surface of said laminated glass, for the fastening of the laminated safety glass to said external support structure. wherein said little plates or studs have a truncated cone shape by which they engage with a corresponding truncated cone surface defined by the holes and the seats, of the first pane, in which said plates and studs are housed, wherein said conical plates or studs have at least one threaded hole, for the fastening of the laminated safety glass to said external support structure, and wherein between said first and said second pane of glass or crystal there is interposed a layer of plastic material, whereby said second pane, together with said layer of plastic material, operates as a contrast element for the plates or stud, holding them firmly in position against such truncated cone surface. - two or more sheets or panes of glass or crystal (5, 6) superimposed one on the other, and - a plurality of little plates or studs that are provided for fastening the laminated glass to an external support structure and are each stably housed in a respective hole or seat formed in said laminated glass,
A method for the calibration and/or monitoring of a flow sensor of a medical system, which is fluidly connected and/or connectable with a compensating volume, with the following steps: - Setting or measuring a first pressure level, - Opening a fluid connection, so that fluid flows through the flow sensor out of or into the compensating volume, - Measuring a first liquid quantity, V3, flowing through the liquid sensor, by means of the flow sensor, - Setting or measuring a second pressure level, - Determining the first liquid quantity, V3, by means of the first and second pressure levels, and - Calibration and/or monitoring of the flow sensor by means of the first liquid quantity measured by means of the flow sensor and the first liquid quantity determined by means of the first and of the second pressure levels, characterized in that an application of the compensation volume with pressure occurs by means of a pump of the medical system, which is present to move a medical liquid within the medical system. - Setting or measuring a first pressure level, - Opening a fluid connection, so that fluid flows through the flow sensor out of or into the compensating volume, - Measuring a first liquid quantity, V3, flowing through the liquid sensor, by means of the flow sensor, - Setting or measuring a second pressure level, - Determining the first liquid quantity, V3, by means of the first and second pressure levels, and - Calibration and/or monitoring of the flow sensor by means of the first liquid quantity measured by means of the flow sensor and the first liquid quantity determined by means of the first and of the second pressure levels, characterized in that an application of the compensation volume with pressure occurs by means of a pump of the medical system, which is present to move a medical liquid within the medical system.