mhurhangee/ep-ind-claims huggingface dataset:
Load-holding valve, comprising: - a body provided with a cavity, - a piston that is bidirectionally movable inside said cavity, - a movable seat positioned inside said cavity and arranged for interacting with said piston such as alternatively to permit a pressurized fluid, or prevent said pressurized fluid from, traversing a passage zone (A s) interposed between said seat and said piston, said seat being hollow and surrounding said piston, - a plurality of openings (3, 4, 5) obtained in said body, through said openings (3, 4, 5) the pressurized fluid being able to enter in, or exit from, said valve and at least one of said openings (3, 4, 5) being suitable for connecting an intermediate portion of said piston with actuating means that is associable with said valve, said intermediate portion being interposed between an end portion of said piston and said seat, characterised in that said end portion has a maximum transverse dimension (D P) that is greater than an internal maximum transverse dimension (D S) of said seat. - a body provided with a cavity, - a piston that is bidirectionally movable inside said cavity, - a movable seat positioned inside said cavity and arranged for interacting with said piston such as alternatively to permit a pressurized fluid, or prevent said pressurized fluid from, traversing a passage zone (A s) interposed between said seat and said piston, said seat being hollow and surrounding said piston, - a plurality of openings (3, 4, 5) obtained in said body, through said openings (3, 4, 5) the pressurized fluid being able to enter in, or exit from, said valve and at least one of said openings (3, 4, 5) being suitable for connecting an intermediate portion of said piston with actuating means that is associable with said valve, said intermediate portion being interposed between an end portion of said piston and said seat,
A process for producing a mutant bacterium which exhibits improved survival and/or growth under a selected growth condition, the process comprising the steps of: (a) generating a pool of mutant bacteria by transposon mutagenesis with two or more different activating transposons (Tn A s), wherein each Tn A comprises a promoter such that transposon insertion into bacterial DNA disrupts the function or increases the transcription of a gene at or near the insertion site in a position-dependent manner, and wherein the transposon mutagenesis yields an insertion rate of at least one transposon per 10 base pairs of bacterial DNA; (b) growing bacteria from the mutant pool under the selected growth condition and under one or more reference conditions to produce two or more test cultures; (c) comparing the distribution of Tn A insertions between test cultures to identify a first class of genes which are disadvantageous for growth and/or survival under the selected growth condition and a second class of genes which are advantageous for growth and/or survival under the selected growth condition; and (d) providing an engineered mutant bacterium in which at least one of said disadvantageous genes is removed or disrupted and/or at least one of said advantageous gene is overexpressed, such that the mutant bacterium exhibits improved survival and/or growth under the selected growth condition. (a) generating a pool of mutant bacteria by transposon mutagenesis with two or more different activating transposons (Tn A s), wherein each Tn A comprises a promoter such that transposon insertion into bacterial DNA disrupts the function or increases the transcription of a gene at or near the insertion site in a position-dependent manner, and wherein the transposon mutagenesis yields an insertion rate of at least one transposon per 10 base pairs of bacterial DNA; (b) growing bacteria from the mutant pool under the selected growth condition and under one or more reference conditions to produce two or more test cultures; (c) comparing the distribution of Tn A insertions between test cultures to identify a first class of genes which are disadvantageous for growth and/or survival under the selected growth condition and a second class of genes which are advantageous for growth and/or survival under the selected growth condition; and (d) providing an engineered mutant bacterium in which at least one of said disadvantageous genes is removed or disrupted and/or at least one of said advantageous gene is overexpressed, such that the mutant bacterium exhibits improved survival and/or growth under the selected growth condition.
Flow sensor, particularly for one-time use, having at least three measuring chambers (11, 15, 19), which are arranged one behind the other, and which are each flowingly connected to one another by a flow resistor (13, 17), wherein for each measuring chamber, a pressure measuring means (12, 16, 20) is provided which is suitable for measuring the pressure (p1, p2, p3) in the corresponding measuring chamber, characterized in that at least two of the flow resistors have a different pressure loss coefficient (ζ1, ζ2).
Body provided with a superficial area adapted to reduce drag when the body is moving relative to a gaseous or watery medium, comprising depressions in said superficial area, wherein the depressions have a greater length than width, wherein the depressions are deprived of sharp edges in a transitional area wherein the depressions meet the superficial area, and that the depressions have a maximum depth relative to the superficial area of 5% of the depressions' width, wherein the depressions are provided with a curvature in a length direction of said depressions so as to cause that in use a turbulent boundary layer of the gaseous or watery medium adjacent to the superficial area is exposed to lateral excitation with reference to a movement direction of the body relative to the gaseous or watery medium or with reference to a flow direction of said turbulent boundary layer along said superficial area of the body.
A packaging machine for packaging articles in packs of plastic film, comprising: a control unit; a wrapping tunnel, adapted to form a tube of plastic film around a group of articles; a feed conveyor, adapted to feed articles to be packaged toward the wrapping tunnel; an elevator, positioned between the feed conveyor and the wrapping tunnel, and movable vertically from a lower position, to receive articles from the feed conveyor, to a higher position, to transfer articles to the wrapping tunnel; a pusher to push articles to be packaged from the elevator into the wrapping tunnel; wherein the pusher is provided with a reciprocating motion of insertion of the articles into the wrapping tunnel and of return to a retracted position with respect to the wrapping tunnel; wherein the movement of the pusher is controlled as a function of the size of the group of articles to be packaged in the direction of insertion into the wrapping tunnel, the packaging machine being characterized in that the control unit is adapted to: - reduce the return stroke of the pusher, with respect to a position of maximum retraction, as a function of the size of the group of articles to be packaged; or - control the movement of the pusher toward the wrapping tunnel so that the pusher carries out a portion of its forward stroke from a position of maximum retraction toward the wrapping tunnel before a lift stroke of the elevator has been completed, said portion of forward stroke being a function of the size of the group of articles to be packaged. a control unit; a wrapping tunnel, adapted to form a tube of plastic film around a group of articles; a feed conveyor, adapted to feed articles to be packaged toward the wrapping tunnel; an elevator, positioned between the feed conveyor and the wrapping tunnel, and movable vertically from a lower position, to receive articles from the feed conveyor, to a higher position, to transfer articles to the wrapping tunnel; a pusher to push articles to be packaged from the elevator into the wrapping tunnel; wherein the pusher is provided with a reciprocating motion of insertion of the articles into the wrapping tunnel and of return to a retracted position with respect to the wrapping tunnel; - reduce the return stroke of the pusher, with respect to a position of maximum retraction, as a function of the size of the group of articles to be packaged; or - control the movement of the pusher toward the wrapping tunnel so that the pusher carries out a portion of its forward stroke from a position of maximum retraction toward the wrapping tunnel before a lift stroke of the elevator has been completed, said portion of forward stroke being a function of the size of the group of articles to be packaged.
System for preparation of beverages presenting at least one system module that comprises - at least one extraction device preferentially disposed in a frontal zone of the system module, and - at least one storage means provided so as to comprise a conduction support that presents a plurality of individual doses and adapted so as to be moved from outside of said storage means and successively supply these individual doses to one, in each case respective, said extraction device, whereby each storage means and respective conduction support are provided so that the conduction support results substantially vertically aligned with a respective said extraction device, above thereof, and - whereby said storage means and respective conduction support are provided so that the conduction support is moved along said vertical alignment, between a storage exit and until said extraction device, preferentially at least until a respective actuation device, characterized in that said conduction support is displaced by means of said respective actuation device disposed in the proximity of the extraction device, between the storage exit and a respective said extraction device, substantially above the latter, and in that said system module is provided so as to include means for separation of the individual dose in each case furthest downstream from the conduction support, disposed between the actuation device and the extraction device or inside of the latter. - at least one extraction device preferentially disposed in a frontal zone of the system module, and - at least one storage means provided so as to comprise a conduction support that presents a plurality of individual doses and adapted so as to be moved from outside of said storage means and successively supply these individual doses to one, in each case respective, said extraction device, whereby each storage means and respective conduction support are provided so that the conduction support results substantially vertically aligned with a respective said extraction device, above thereof, and - whereby said storage means and respective conduction support are provided so that the conduction support is moved along said vertical alignment, between a storage exit and until said extraction device, preferentially at least until a respective actuation device,
A method of producing non-alcoholic perfumes characterized in that in the first place, in order to obtain a pre-emulsion, a certain amount of oil phase consisting of a fragrance composition and emulsifier and an aqueous phase, being a mixture of water and preservative, is dispersed using a mechanical stirrer with a rotational speed of agitators from 450 to 550 rpm for 10 to 15 minutes, wherein the process is carried out at a temperature of 20°C to 30°C, and the obtained pre-emulsion is then subjected to a homogenization process using an ultrasonic probe with a sonication power of 10 to 30 W, wherein the time for the homogenization process is determined by obtaining a transparent system and the oil phase is obtained by combining from 5 to 10% by weight of an emulsifier and 5 to 15% by weight of a fragrance composition, the weight ratio S: O of the emulsifier to the fragrance composition ranging from 1: 1 to 1: 3, on the other hand, the aqueous phase is obtained by combining the preservative in an amount of 0.00025 to 1% by weight with water in an amount to make up to 100% by weight of the ingredients.
An electrochromic element which is a single layer graded composition comprising a stack of a first region of transparent conductive material, a region of EC material, a region of ion conducting material, a region of counter electrode material, and a second region of transparent conductive material, respectively, wherein the EC element is all inorganic, and wherein the first region of transparent conductive material is graded into the region of EC material, which is graded into the region of IC material which is graded into the region of CE material, which is graded into the second region of transparent conductive material.
A gateway server to facilitate supervision of an online identity, the gateway server comprising: a profile database to store access information to online services of a user of a client computing device, wherein the access information is inaccessible by the user of the client computing device; a policy database to store a set of policy rules that define authorized activity between the client computing device and the online services; an identity manager module to (i) receive a request for access to an online service from the client computing device, (ii) retrieve, in response to the request, access information to the online service from the profile database, wherein to retrieve the access information comprises to retrieve login information usable by the gateway server to login the user of the client computing device with the online service, and (iii) facilitate access to the online service for the client computing device using the access information; and an activity monitor module to control activity between the client computing device and the online service based on the set of policy rules, wherein to control activity between the client computing device and the online service comprises to control the disclosure of identity profile information of the user of the client computing device to the online service based on a profile disclosure policy of the policy database. a profile database to store access information to online services of a user of a client computing device, wherein the access information is inaccessible by the user of the client computing device; a policy database to store a set of policy rules that define authorized activity between the client computing device and the online services; an identity manager module to (i) receive a request for access to an online service from the client computing device, (ii) retrieve, in response to the request, access information to the online service from the profile database, wherein to retrieve the access information comprises to retrieve login information usable by the gateway server to login the user of the client computing device with the online service, and (iii) facilitate access to the online service for the client computing device using the access information; and an activity monitor module to control activity between the client computing device and the online service based on the set of policy rules, wherein to control activity between the client computing device and the online service comprises to control the disclosure of identity profile information of the user of the client computing device to the online service based on a profile disclosure policy of the policy database.
A polymeric composition, comprising: an ethylene-based polymer having a density of 0.926 g/cc to 0.970 g/cc as measured according to ASTM D792; and a polydimethylsiloxane having a weight average molecular weight of 550,000 g/mol to 650,000 g/mol as measured according to Gel Permeation Chromatography, wherein the composition is free of polydimethylsiloxane having a weight average molecular weight of from 30,000 g/mol to 300,000 g/mol as measured according to Gel Permeation Chromatography. an ethylene-based polymer having a density of 0.926 g/cc to 0.970 g/cc as measured according to ASTM D792; and a polydimethylsiloxane having a weight average molecular weight of 550,000 g/mol to 650,000 g/mol as measured according to Gel Permeation Chromatography, wherein the composition is free of polydimethylsiloxane having a weight average molecular weight of from 30,000 g/mol to 300,000 g/mol as measured according to Gel Permeation Chromatography.
A cyanoacrylate composition comprising: (a) a cyanoacrylate component; (b) a toughening agent comprising an ethylene-vinyl acetate copolymer comprising 30 wt% vinyl acetate to 95 wt% vinyl acetate based on the total weight of the copolymer; (c) a component having at least two (meth)acrylate functional groups having the formula: wherein R 1 and R 2 are the same or different and are selected from the group consisting of H or Me; and wherein X is a C 4 to C 30 alkyl chain and wherein said chain is optionally substituted with one or more acrylate and/or methacrylate functional groups, and/or one or more C 1 -C 10 alkyl groups; (d) a benzonitrile component; and (e) an anhydride component. (a) a cyanoacrylate component; (b) a toughening agent comprising an ethylene-vinyl acetate copolymer comprising 30 wt% vinyl acetate to 95 wt% vinyl acetate based on the total weight of the copolymer; (c) a component having at least two (meth)acrylate functional groups having the formula: wherein R 1 and R 2 are the same or different and are selected from the group consisting of H or Me; and wherein X is a C 4 to C 30 alkyl chain and wherein said chain is optionally substituted with one or more acrylate and/or methacrylate functional groups, and/or one or more C 1 -C 10 alkyl groups; (d) a benzonitrile component; and (e) an anhydride component.
An anti-cancer therapy for use in a method of treating cancer in a subject comprising: (a) measuring in a biological sample from the subject the level of: (i) Dicer in an exosome fraction of the sample; and/or (ii) Dicer processing activity of a primary miRNA or precursor miRNA in an exosome fraction of the sample; (b) identifying the subject having or not having a cancer biomarker by comparing the level of Dicer or Dicer processing activity in the sample from the subject to the level of Dicer or Dicer processing activity in a reference sample; and (c) administering an anti-cancer agent to the subject having increased levels of Dicer or Dicer processing activity relative to the reference sample. (a) measuring in a biological sample from the subject the level of: (i) Dicer in an exosome fraction of the sample; and/or (ii) Dicer processing activity of a primary miRNA or precursor miRNA in an exosome fraction of the sample; (i) Dicer in an exosome fraction of the sample; and/or (ii) Dicer processing activity of a primary miRNA or precursor miRNA in an exosome fraction of the sample; (b) identifying the subject having or not having a cancer biomarker by comparing the level of Dicer or Dicer processing activity in the sample from the subject to the level of Dicer or Dicer processing activity in a reference sample; and (c) administering an anti-cancer agent to the subject having increased levels of Dicer or Dicer processing activity relative to the reference sample.
A method for the finished-product related production and further processing of mixtures of chlorinated polysilane for the generation of silicon and/or silicon-based products, characterized in that, depending on the generated polysilane mixture of low-molecular-weight polysilanes having 2 to 6 silicon atoms, medium-molecular-weight polysilanes having 7 to 14 silicon atoms or high-molecular-weight polysilanes having at least 15 silicon atoms and the desired finished product and/or intermediate product, the chlorinated polysilane mixtures are produced plasma-chemically from SiCl 4 and H 2, and wherein the plasma sources used in the plasma reactor are pulsed and the plasma in the plasma reactor is periodically quenched by an additional alternating electromagnetic field, wherein the polysilane mixture is a polymeric dichlorosilane having the empirical formula SiCl 2+x, which consists of rings (x=0) with the molecular formula Si n Cl 2n and chains (0 < x ≤ 1) with the molecular formula Si n Cl 2n+2, wherein the chains terminate with -SiCl 3 groups and wherein the method is performed continuously.
Seal arrangement for a fluid valve, comprising: a first, separate sealing element for sealing abutment against a pivotably adjustable valve body of the fluid valve, a second, separate sealing element for sealing abutment against a valve housing of the fluid valve, and a separate, elastically deformable intermediate piece, which is arranged, in an axial direction (X - X) of the seal arrangement, between a first wall of the first sealing element and a second wall of the second sealing element for elastically spacing apart the two sealing elements (4, 6), wherein the second wall is situated opposite the first wall, wherein, on the first wall, there is furthermore integrally formed a projection arrangement, against which the intermediate piece is able to be brought into abutment under a load, wherein the projection arrangement is arranged inside the intermediate piece in relation to a seal opening, such that the intermediate piece sealingly encloses the projection arrangement, wherein the intermediate piece has at least one axial section whose cross section has, in relation to the seal opening, a first, radially outer lateral surface and an oppositely situated second, radially inner lateral surface, wherein the radially outer lateral surface is at least sectionally concave, and the radially inner lateral surface is at least sectionally convex, characterized in that the cross section of the intermediate piece describes a pressure-activatable V shape which, under a load, realizes both axial, elastic compression and bending in a region around a cross-sectional centre of the intermediate piece. a first, separate sealing element for sealing abutment against a pivotably adjustable valve body of the fluid valve, a second, separate sealing element for sealing abutment against a valve housing of the fluid valve, and a separate, elastically deformable intermediate piece, which is arranged, in an axial direction (X - X) of the seal arrangement, between a first wall of the first sealing element and a second wall of the second sealing element for elastically spacing apart the two sealing elements (4, 6), wherein the second wall is situated opposite the first wall, wherein, on the first wall, there is furthermore integrally formed a projection arrangement, against which the intermediate piece is able to be brought into abutment under a load, wherein the projection arrangement is arranged inside the intermediate piece in relation to a seal opening, such that the intermediate piece sealingly encloses the projection arrangement, wherein the intermediate piece has at least one axial section whose cross section has, in relation to the seal opening, a first, radially outer lateral surface and an oppositely situated second, radially inner lateral surface, wherein the radially outer lateral surface is at least sectionally concave, and the radially inner lateral surface is at least sectionally convex, characterized in that the cross section of the intermediate piece describes a pressure-activatable V shape which, under a load, realizes both axial, elastic compression and bending in a region around a cross-sectional centre of the intermediate piece.
A method for producing an alkoxyindanone derivative represented by a general formula in Figure 2, wherein R represents an alkoxy group containing 1 to 6 carbon atoms and n represents an integer of 1 to 4, comprising: reacting an alkoxyphenylpropionic acid derivative represented by a general formula in Figure 1 wherein R and n are as defined above, with a condensing agent; adding an organic solvent to the resulting reaction mixture; and then decomposing the condensing agent with an aqueous alkaline solution. reacting an alkoxyphenylpropionic acid derivative represented by a general formula in Figure 1 wherein R and n are as defined above, with a condensing agent; adding an organic solvent to the resulting reaction mixture; and then decomposing the condensing agent with an aqueous alkaline solution.