mhurhangee/ep-ind-claims huggingface dataset:
Chemical-pharmaceutical conjugates of hyaluronic acid and/or its derivatives obtained through an indirect binding between the polysaccharide and a drug with an antitumoral action, via a molecular spacer which forms an ester bond with the carboxylic group of HA and/or its derivative, with the proviso that said spacer is not a hydrazide or a polypeptide, the drug being a nitrosourea, and the derivative of hyaluronic acid being selected from - HA salified with organic and/or inorganic bases having a molecular weight of 50-730KDa or a high molecular weight 750-1230 KDa; - esters of HA with alcohols of the aliphatic, araliphatic, cyclo-aliphatic, aromatic, cyclic and heterocyclic series, with an esterification percentage which vary depending on the type and length of alcohol used, from 1 to 75%; - amides of HA with amines of the aliphatic, araliphatic, cyclo-aliphatic, aromatic, cyclic and heterocyclic series, with an amidation percentage ranging from 1 to 10%; - O-sulfated derivatives of HA up to the 4th sulfation degree; - internal esters of HA with an internal esterification percentage ranging from 0.5 to 10% and preferably 5%; - deacetylates of HA deriving from the deacetylation of the N-acetyl-glucosamine fraction with a deacetylation percentage preferably ranging from 0.1 to 30%; - percarboxylated derivatives of HA obtained from the oxidation of the primary hydroxyl of the N-acetyl-glucosamine fraction with a percarboxylation degree ranging from 0.1 to 100%. - HA salified with organic and/or inorganic bases having a molecular weight of 50-730KDa or a high molecular weight 750-1230 KDa; - esters of HA with alcohols of the aliphatic, araliphatic, cyclo-aliphatic, aromatic, cyclic and heterocyclic series, with an esterification percentage which vary depending on the type and length of alcohol used, from 1 to 75%; - amides of HA with amines of the aliphatic, araliphatic, cyclo-aliphatic, aromatic, cyclic and heterocyclic series, with an amidation percentage ranging from 1 to 10%; - O-sulfated derivatives of HA up to the 4th sulfation degree; - internal esters of HA with an internal esterification percentage ranging from 0.5 to 10% and preferably 5%; - deacetylates of HA deriving from the deacetylation of the N-acetyl-glucosamine fraction with a deacetylation percentage preferably ranging from 0.1 to 30%; - percarboxylated derivatives of HA obtained from the oxidation of the primary hydroxyl of the N-acetyl-glucosamine fraction with a percarboxylation degree ranging from 0.1 to 100%.
A wheelchair assembly (100, 200) for easy assembly and disassembly, the wheelchair assembly comprising: a plurality of frames (106, 108, 110, 206, 208, 210); at least one motor; a battery; and a plurality of wheels (116, 118, 120, 216, 218, 220A), wherein the wheelchair assembly includes a plurality of subassemblies (202, 204), wherein each of the plurality of subassemblies weighs less than thirty-five, 35, kilograms, and wherein each of the plurality of subassemblies are configured to be selectively attached or disassembled with each other to form the wheelchair assembly. a plurality of frames (106, 108, 110, 206, 208, 210); at least one motor; a battery; and a plurality of wheels (116, 118, 120, 216, 218, 220A), wherein the wheelchair assembly includes a plurality of subassemblies (202, 204), wherein each of the plurality of subassemblies weighs less than thirty-five, 35, kilograms, and wherein each of the plurality of subassemblies are configured to be selectively attached or disassembled with each other to form the wheelchair assembly.
A soft magnetic powdered core comprising a green compact of a powder mixture comprising a soft magnetic powder and an insulating powder lubricant in an amount of 0.1 to 0.7 % by mass to the soft magnetic powder, wherein the insulating powder lubricant comprises at least one selected from the group consisting of barium stearate and lithium stearate, characterized in that the insulating powder lubricant has an average particle size of 45 μm or less and the green compact has a space factor of the soft magnetic powder of 93 % or more and a specific electrical resistance of 10000 μΩcm or more.
An immunoassay analyzer, comprising: - a mixing device (100, 101, 102) having a first station and a second station, the mixing device (100, 101, 102) comprising at least one delivering assembly and at least two mixing assemblies, and wherein the at least one delivering assembly is configured to drive the mixing assemblies to cyclically reciprocate between the first station and the second station, each mixing assembly is configured to carry a reactor and mix a sample and a reagent in the reactor as part of a sequence of actions, characterized by each mixing assembly including a support base, a driver and a carrying platform driven by the driver; and - a reaction device configured to perform an incubation, a BF operation, and a measurement to a reactant in the reactor, and the reaction device comprising a rotating disk wherein: - a shortest time window during which the sequence of actions performed by the mixing assembly is reproduced cyclically is recorded as a first period; and a value obtained by dividing the first period by the number of mixing assemblies is recorded as a second period; and - the immunoassay analyzer is configured such as that from when the reactor is moved into one of the mixing assemblies for the first time, the reactors are moved into each of the other mixing assemblies sequentially at staggered intervals of one second period; the reactors that have been mixed are moved out of the mixing assembly and onto the rotating disk by sequentially staggering the time of the second period; new reactors are moved into the mixing assembly from which the reactors are removed. - a mixing device (100, 101, 102) having a first station and a second station, the mixing device (100, 101, 102) comprising at least one delivering assembly and at least two mixing assemblies, and wherein the at least one delivering assembly is configured to drive the mixing assemblies to cyclically reciprocate between the first station and the second station, each mixing assembly is configured to carry a reactor and mix a sample and a reagent in the reactor as part of a sequence of actions, characterized by each mixing assembly including a support base, a driver and a carrying platform driven by the driver; and - a reaction device configured to perform an incubation, a BF operation, and a measurement to a reactant in the reactor, and the reaction device comprising a rotating disk - a shortest time window during which the sequence of actions performed by the mixing assembly is reproduced cyclically is recorded as a first period; and a value obtained by dividing the first period by the number of mixing assemblies is recorded as a second period; and - the immunoassay analyzer is configured such as that from when the reactor is moved into one of the mixing assemblies for the first time, the reactors are moved into each of the other mixing assemblies sequentially at staggered intervals of one second period; the reactors that have been mixed are moved out of the mixing assembly and onto the rotating disk by sequentially staggering the time of the second period; new reactors are moved into the mixing assembly from which the reactors are removed.
Siphon for closing an outlet pipe, the siphon comprising a housing with an inflow opening arranged in a housing wall, an outflow opening arranged in a housing wall and a separating wall directed downward from above between the inflow opening and the outflow opening and having a passage opening, wherein the passage opening lies in a lower position than both the inflow opening and the outflow opening, wherein a flexible wall part is provided, wherein the separating wall has a length such that it extends below the inflow an outflow openings (3, 4), to provide a water seal having a first height (h 1), and wherein the flexible wall part comprises a flexible flap, characterized in that the flexible flap is arranged as a unidirectional seal and is provided in the passage opening under the separating wall, which flexible flap lengthens the separating wall to increase the water seal height to a second height (h 2), wherein the flexible flap is arranged with an end on the separating wall and lying with a free end against an opposite housing wall.
A welding metal having excellent low-temperature toughness and drop-weight characteristics, consisting of: C of 0.02% to 0.10% (by mass percent, the same holds true for each chemical component composition described below); Si of 0.50% or less (excluding 0%); Mn of 1.0% to 1.9%; Ni of 2.7% to 8%; Cr of 0.8% or less (excluding 0%); Mo of 0.8% or less (excluding 0%); N of 0.010% or less (excluding 0%); and O of 0.010% or less (excluding 0%), wherein the total content of Cr and Mo is 0.10% to 1.2%, and optionnally of, as another element, at least one selected from the following groups to: Ti of 0.040% or less (excluding 0%); A1 of 0.030% or less (excluding 0%); Cu of 0.35% or less (excluding 0%); and at least one selected from a group consisting of Nb of 0.030% or less (excluding 0%) and V of 0.10% or less (excluding 0%), the remainder consists of iron and inevitable impurities, an A value as specified by formula is 3.8% to 9.0%, and surface area percentage of carbide having a circle-equivalent diameter of 0.20 μm or greater in the welding metal is 4.0% or less, the formula being expressed as follows: A value = 0.8 × C − 0.05 × Si + 0.5 × Mn + 0.5 × Cu + Ni − 0.5 × Mo + 0.2 × Cr, where, [Si], [Mn], [Cu], [Ni], [Mo] and [Cr] are contents (by mass percent) of C, Si, Mn, Cu, Ni, Mo and Cr, respectively. C of 0.02% to 0.10% (by mass percent, the same holds true for each chemical component composition described below); Si of 0.50% or less (excluding 0%); Mn of 1.0% to 1.9%; Ni of 2.7% to 8%; Cr of 0.8% or less (excluding 0%); Mo of 0.8% or less (excluding 0%); N of 0.010% or less (excluding 0%); and O of 0.010% or less (excluding 0%), Ti of 0.040% or less (excluding 0%); A1 of 0.030% or less (excluding 0%); Cu of 0.35% or less (excluding 0%); and at least one selected from a group consisting of Nb of 0.030% or less (excluding 0%) and V of 0.10% or less (excluding 0%),
Patch array antenna for a portable stable low-mass microwave radiometer for measuring microwaves in the spectral range between 1 and 300 GHz, connectable to a radiometer electronics, characterized in that the patch array antenna comprises at least one patch array (10, 10') with a patch substrate layer (100, 100') in form of a printed circuit board of a dielectric material on which a pattern of printed patches (101, 101') is printed on a front side of the patch substrate layer (100, 100'), wherein the printed patches (101, 101') are interconnected via inset-feeds (102, 102') to strip lines (103, 103') on the same plane as the printed circuit board printed patches (101, 101'), wherein connector lines are connected to the strip lines (103, 103') and fed through the patch substrate layer (100, 100') through a ground conductor layer (108, 108'), which is spaced apart fixed to the backside of the patch substrate layer (100, 100') at a defined distance (d, d') forming an air gap (106, 106') only between both layers (100, 100', 108, 108'), wherein the air gap (106, 106') is formed by a multiplicity of individual single spacers (107, 107'), and such that the connector lines (1030, 1030') are led through the ground conductor layer (108, 108') into at least one RF coaxial connector (104, 104') fixed at a backside of the ground conductor layer (108, 108'), which is or are directly without detour connectable via cables with the radiometer electronics. the patch array antenna comprises at least one patch array (10, 10') with a patch substrate layer (100, 100') in form of a printed circuit board of a dielectric material on which a pattern of printed patches (101, 101') is printed on a front side of the patch substrate layer (100, 100'), wherein the printed patches (101, 101') are interconnected via inset-feeds (102, 102') to strip lines (103, 103') on the same plane as the printed circuit board printed patches (101, 101'), wherein connector lines are connected to the strip lines (103, 103') and fed through the patch substrate layer (100, 100') through a ground conductor layer (108, 108'), which is spaced apart fixed to the backside of the patch substrate layer (100, 100') at a defined distance (d, d') forming an air gap (106, 106') only between both layers (100, 100', 108, 108'), wherein the air gap (106, 106') is formed by a multiplicity of individual single spacers (107, 107'), and such that the connector lines (1030, 1030') are led through the ground conductor layer (108, 108') into at least one RF coaxial connector (104, 104') fixed at a backside of the ground conductor layer (108, 108'), which is or are directly without detour connectable via cables with the radiometer electronics.
A biometrics sensor comprising: a sucking section arranged to suck air in the vicinity of an object person for measurement; a molecular sieve portion arranged to selectively pass or absorb a specific gas component contained in the sucked air; a gas detecting section arranged to detect a concentration of the specific gas component selectively absorbed into the molecular sieve portion and remaining in the gas passed through the molecular sieve portion; and a data processing section arranged to compare a detection result of the gas detecting section and a prestored detection result; wherein the molecular sieve portion comprises a plurality of filters: a molecular sieve arranged to selectively pass or absorb a specific gas component contained in the sucked air on the basis of molecule sizes and an alkali bead arranged to selectively pass or absorb a specific gas component contained in the sucked air on the basis of an acid functionality. a sucking section arranged to suck air in the vicinity of an object person for measurement; a molecular sieve portion arranged to selectively pass or absorb a specific gas component contained in the sucked air; a gas detecting section arranged to detect a concentration of the specific gas component selectively absorbed into the molecular sieve portion and remaining in the gas passed through the molecular sieve portion; and a data processing section arranged to compare a detection result of the gas detecting section and a prestored detection result;
Method for producing hardened steel components, wherein a blank is cut from a galvanized strip made of a hardenable steel alloy, and the blanks are subsequently cold-formed into a component blank and then heated to a temperature that causes a structural change to austenite, wherein the austenitized component blank is then fed to a shaping and hardening tool, in which the component blank is held in a form-fitting manner by means of an upper and lower tool that have a shape that substantially corresponds to the component blank, wherein by placing the material of the component blank against the particularly cooled tools, the heat is extracted from the steel material so quickly that martensitic hardening takes place, characterized in that, after the metal strip has been galvanized and before the temperature increase for the purpose of austenitization, tin is applied to the surface of the strip or the blank or the component blank.
Spin-stabilised artillery projectile with a driving band or a driving band structure and at least one obturator (12, 13), wherein the driving band, seen in the direction of a longitudinal axis of the projectile, contains at least one compensating groove (8, 9), and wherein which at least one obturator (12, 13) is arranged in the compensating groove (8, 9) of the driving band, wherein the at least one obturator (12, 13) consists of plastic and the driving band is metallic, wherein the driving band is designed in such a way that when passing through the barrel the backward-oriented driving band material pushes the at least one obturator (12, 13) upwards out of the at least one compensating groove (8, 9), like an O-ring, and the metallic driving band region behind the positioning of the obturator (12, 13) shears this off.
Rail vehicle car (4, 30, 32, 36) with a plurality of side wall modules embodied as window modules (6, 8), wherein all window modules (6, 8) in each case have either a first width (b 1) or a smaller second width (b 2), wherein at least one of the window modules has the first width (b 1) and at least one of the window modules has the second width (b 2), characterised in that the second width (b 2) is reduced by at least 15 % and by at most 25 % compared to the first width (b 1). all window modules (6, 8) in each case have either a first width (b 1) or a smaller second width (b 2), wherein at least one of the window modules has the first width (b 1) and at least one of the window modules has the second width (b 2), characterised in that the second width (b 2) is reduced by at least 15 % and by at most 25 % compared to the first width (b 1).
A supercritical refrigeration cycle system of vapor compression type with the high pressure in the refrigeration cycle reaching and exceeding the critical pressure of a refrigerant, comprising: a compressor for sucking in and compressing the refrigerant; a radiator for radiating the heat of the high-pressure refrigerant discharged from the compressor; a plurality of decompressors (5, 12) including a first decompressor and a second decompressor into which the high-pressure refrigerant discharged from the radiator and distributed flows; a first evaporator for evaporating the refrigerant decompressed by the first decompressor; and a second evaporator for evaporating the refrigerant decompressed by the second decompressor; wherein the refrigerant flowing out of one of the first evaporator and the second evaporator flows into the other evaporator, characterised in that said first decompressor and second decompressor are connected in parallel. a compressor for sucking in and compressing the refrigerant; a radiator for radiating the heat of the high-pressure refrigerant discharged from the compressor; a plurality of decompressors (5, 12) including a first decompressor and a second decompressor into which the high-pressure refrigerant discharged from the radiator and distributed flows; a first evaporator for evaporating the refrigerant decompressed by the first decompressor; and a second evaporator for evaporating the refrigerant decompressed by the second decompressor; wherein the refrigerant flowing out of one of the first evaporator and the second evaporator flows into the other evaporator, characterised in that said first decompressor and second decompressor are connected in parallel.
A heating element comprising: a substrate; a conductive heating pattern provided on the substrate; and two bus bars provided so as to apply voltage to both ends of the conductive heating pattern, respectively, wherein the conductive heating pattern comprises a pattern in which the number of lines is determined in at least some regions in a pattern comprising some of the lines connecting vertices and constituting a border of a closed figure having at least three vertices, according to a distance from the bus bar, and wherein the conductive heating pattern comprises at least two regions having different average numbers of lines per unit area, an aperture ratio for each region is 90% or more, and an aperture ratio difference between regions is 2% or less, and wherein a value, which is obtained by converting an area, which the pattern comprising lines constituting the border of the closed figure does not occupy, into a ratio with respect to the total area of the region is defined as the aperture ratio, characterized in that the closed figure is a figure in which at least one of a position of a vertex of a regular polygon having six vertices, and a curvature degree of lines thereof is modified. a substrate; a conductive heating pattern provided on the substrate; and two bus bars provided so as to apply voltage to both ends of the conductive heating pattern, respectively, wherein the conductive heating pattern comprises a pattern in which the number of lines is determined in at least some regions in a pattern comprising some of the lines connecting vertices and constituting a border of a closed figure having at least three vertices, according to a distance from the bus bar, and wherein the conductive heating pattern comprises at least two regions having different average numbers of lines per unit area, an aperture ratio for each region is 90% or more, and an aperture ratio difference between regions is 2% or less, and wherein a value, which is obtained by converting an area, which the pattern comprising lines constituting the border of the closed figure does not occupy, into a ratio with respect to the total area of the region is defined as the aperture ratio, characterized in that the closed figure is a figure in which at least one of a position of a vertex of a regular polygon having six vertices, and a curvature degree of lines thereof is modified.
An in vitro method of assaying the lytic potential of a population of immune effector cells comprising the steps consisting of i) contacting the population of immune effector cells with a population of target cells for a sufficient period of time and under conditions suitable for allowing the population of immune effector cells to induce a cytotoxic response, ii) measuring the reparative membrane turnover level in the population of target cells by measuring the uptake of a fluorescent lipophilic dye by the population of target cells, wherein said level correlates with the lytic potential of the population of immune effector cells and wherein the fluorescent lipophilic dye is a styryl dye.
LED floodlight fixture including an LED assembly which has a plurality of LED-array modules separately mounted on corresponding individual heat sinks, each heat sink having a module-engaging surface and a heat-dissipating surface with each LED module against the corresponding module-engaging surface, characterized in that the LED floodlight fixture is arranged to permit air and water flow from the heat sink and the individual heat sinks of the LED assembly are interconnected to hold the LED-array modules in fixed relative positions.
Packaging for foods, pharmaceuticals or cosmetics for detecting the growth of bacteria, molds and yeasts in foods, pharmaceuticals or cosmetics, without the need of direct contact with said foods, pharmaceuticals or cosmetics contained in the inner gaseous atmosphere of that packaging, characterized in that this packaging is made of transparent and colorless material and further that it comprises a sensor in form of a partially polar adsorbent solid support capable of absorbing humidity, with a surface layer containing vanillin, said sensor being attached to the inner side of said packaging and visible from outside the packaging for indicating microbes in the packaged foods, pharmaceuticals or cosmetics by changing the color of this visible sensor.
A coating composition comprising: (a) a polyether polyol having a hydroxyl functionality of 3 to 8 comprising a reaction product of a reaction mixture comprising a saccharide and an alkylene oxide, and (b) a reaction product of: (i) a phosphorus acid, and (ii) a polyepoxide and/or a polyester polyol, wherein the coating composition is substantially free of bisphenol A and derivatives of bisphenol A. (a) a polyether polyol having a hydroxyl functionality of 3 to 8 comprising a reaction product of a reaction mixture comprising a saccharide and an alkylene oxide, and (b) a reaction product of: (i) a phosphorus acid, and (ii) a polyepoxide and/or a polyester polyol, (i) a phosphorus acid, and (ii) a polyepoxide and/or a polyester polyol,