An omnidirectional scientific toothbrush, comprising: a brush handle, and a brush head, wherein the brush head has a U-shaped structure, a central gearset, and tooth outer side brush rollers, tooth inner side brush rollers and one tooth end surface brush roller which are driven by the central gearset are installed in an inner cavity of the brush head; the tooth outer side brush rollers and the tooth inner side brush rollers are both arranged in an upper row and a lower row which are opposite according to a tooth layout in an oral cavity of human body, and main body parts of each tooth outer side brush roller and each tooth inner side brush roller are both flexible roller bars, a side brush roller gear is fixedly connected to each flexible roller bar, and bristles are planted onto the flexible roller bars at two sides of the side brush roller gear, the tooth end surface brush roller is located in a space defined by the tooth outer side brush rollers and the tooth inner side brush rollers; a main body part of the tooth end surface brush roller is a flexible roller bar, a flexible cord is provided in the flexible roller bar and bristles are planted onto the flexible roller bar; and a power output mechanism driven by a micro motor is arranged in the brush handle, the power output mechanism drives the central gearset to move to allow the tooth outer side brush roller and the tooth inner side brush roller located at two sides of the same tooth to rotate in opposite directions and to have rotating directions which are both from a tooth root to a tooth end, and rotation of the tooth end surface brush roller allows the tooth end surface brush roller to simultaneously brush occlusal surfaces of upper and lower teeth in the oral cavity. a brush handle, and a brush head, wherein the brush head has a U-shaped structure, a central gearset, and tooth outer side brush rollers, tooth inner side brush rollers and one tooth end surface brush roller which are driven by the central gearset are installed in an inner cavity of the brush head; the tooth outer side brush rollers and the tooth inner side brush rollers are both arranged in an upper row and a lower row which are opposite according to a tooth layout in an oral cavity of human body, and main body parts of each tooth outer side brush roller and each tooth inner side brush roller are both flexible roller bars, a side brush roller gear is fixedly connected to each flexible roller bar, and bristles are planted onto the flexible roller bars at two sides of the side brush roller gear, the tooth end surface brush roller is located in a space defined by the tooth outer side brush rollers and the tooth inner side brush rollers; a main body part of the tooth end surface brush roller is a flexible roller bar, a flexible cord is provided in the flexible roller bar and bristles are planted onto the flexible roller bar; and a power output mechanism driven by a micro motor is arranged in the brush handle, the power output mechanism drives the central gearset to move to allow the tooth outer side brush roller and the tooth inner side brush roller located at two sides of the same tooth to rotate in opposite directions and to have rotating directions which are both from a tooth root to a tooth end, and rotation of the tooth end surface brush roller allows the tooth end surface brush roller to simultaneously brush occlusal surfaces of upper and lower teeth in the oral cavity.