An open cavity, reduced pressure treatment system for treating a body cavity, comprising: a treatment device, comprising: a plurality of encapsulated leg members, each encapsulated leg member having an interior portion with a leg manifold member positioned therein, the plurality of encapsulated leg members including fenestrations (114, 116) to allow fluid flow between an outer surface of the encapsulated leg members and the interior portion, and a central connection member having a connection manifold member, wherein the plurality of leg manifold members are in fluid communication with the connection manifold member, and wherein the central connection member comprises a first connection encapsulation member formed with fenestrations and having a peripheral edge; a second connection encapsulation member formed with fenestrations; and wherein the peripheral edge of the first connection encapsulation member is coupled at least in part to the second connection encapsulation member; a manifold for disposing proximate the first connection encapsulation member, such that when a reduced pressure is applied to the manifold, the reduced pressure causes fluid to flow from the connection manifold member through the fenestrations of the first connection encapsulation member into the manifold; and a sealing member operable to form a pneumatic seal over the body cavity. a treatment device, comprising: a plurality of encapsulated leg members, each encapsulated leg member having an interior portion with a leg manifold member positioned therein, the plurality of encapsulated leg members including fenestrations (114, 116) to allow fluid flow between an outer surface of the encapsulated leg members and the interior portion, and a central connection member having a connection manifold member, wherein the plurality of leg manifold members are in fluid communication with the connection manifold member, and wherein the central connection member comprises a first connection encapsulation member formed with fenestrations and having a peripheral edge; a second connection encapsulation member formed with fenestrations; and wherein the peripheral edge of the first connection encapsulation member is coupled at least in part to the second connection encapsulation member; a manifold for disposing proximate the first connection encapsulation member, such that when a reduced pressure is applied to the manifold, the reduced pressure causes fluid to flow from the connection manifold member through the fenestrations of the first connection encapsulation member into the manifold; and a plurality of encapsulated leg members, each encapsulated leg member having an interior portion with a leg manifold member positioned therein, the plurality of encapsulated leg members including fenestrations (114, 116) to allow fluid flow between an outer surface of the encapsulated leg members and the interior portion, and a central connection member having a connection manifold member, wherein the plurality of leg manifold members are in fluid communication with the connection manifold member, and wherein the central connection member comprises a first connection encapsulation member formed with fenestrations and having a peripheral edge; a second connection encapsulation member formed with fenestrations; and wherein the peripheral edge of the first connection encapsulation member is coupled at least in part to the second connection encapsulation member; a manifold for disposing proximate the first connection encapsulation member, such that when a reduced pressure is applied to the manifold, the reduced pressure causes fluid to flow from the connection manifold member through the fenestrations of the first connection encapsulation member into the manifold; and a sealing member operable to form a pneumatic seal over the body cavity.