mhurhangee/ep-ind-claims huggingface dataset:
A composition for use in treating a bacterial infection in a subject comprising a pharmaceutically acceptable carrier and an effective amount of a compound represented by any one of the following formulae, or a pharmaceutically acceptable salt thereof:
A damping mechanism, comprising: a torsion spring, wherein the torsion spring comprises a first pin and a second pin; a first fixing member, wherein the first fixing member is rotatably connected to the second pin in a first direction; and a first swinging member, wherein the first swinging member comprises a first fixing portion and a first moving portion, and the first fixing portion is rotatably connected to the first fixing member in the first direction; the first moving portion is rotatably connected to the first pin in the first direction; when rotation is performed between the first fixing member and the first swinging member, an elastic force generated by the torsion spring acts on a center of rotation in which the first moving portion is rotatably connected to the first pin, forming an unfolding force or a closing force, wherein the damping mechanism further comprises a limiting slider assembly and an accommodating groove used to accommodate the limiting slider assembly, wherein the accommodating groove is provided on a side surface of the first swinging member in a second direction; the first pin is rotatably connected to the limiting slider assembly in the first direction; the limiting slider assembly is slidably connected to the accommodating groove in the second direction, to drive the first pin to move in the second direction; and the second direction is perpendicular to the first direction. a torsion spring, wherein the torsion spring comprises a first pin and a second pin; a first fixing member, wherein the first fixing member is rotatably connected to the second pin in a first direction; and a first swinging member, wherein the first swinging member comprises a first fixing portion and a first moving portion, and the first fixing portion is rotatably connected to the first fixing member in the first direction; the first moving portion is rotatably connected to the first pin in the first direction; when rotation is performed between the first fixing member and the first swinging member, an elastic force generated by the torsion spring acts on a center of rotation in which the first moving portion is rotatably connected to the first pin, forming an unfolding force or a closing force, wherein the damping mechanism further comprises a limiting slider assembly and an accommodating groove used to accommodate the limiting slider assembly, wherein the accommodating groove is provided on a side surface of the first swinging member in a second direction; the first pin is rotatably connected to the limiting slider assembly in the first direction; the limiting slider assembly is slidably connected to the accommodating groove in the second direction, to drive the first pin to move in the second direction; and the second direction is perpendicular to the first direction.
A pharmaceutical composition comprising: (a) a rAAV2 variant comprising an amino acid sequence LGETTRP inserted between positions 587 and 588 of capsid protein VP1, a nucleic acid encoding: (i) a sequence having at least 95% identity to SEQ ID NO: 9; and (ii) a sequence having at least 95% identity to SEQ ID NO: 10, and (b) a pharmaceutically acceptable excipient; for use in method of treating an eye disease or condition selected from: neovascular (wet) age-related macular degeneration, choroidal neovascularization, macular edema following retinal vein occlusion, diabetic macular edema, retinal vein occlusion, and diabetic retinopathy associated with DME, the method comprising administering a unit dose of the pharmaceutical composition by intravitreal injection to an eye of a primate subject in need thereof. (a) a rAAV2 variant comprising an amino acid sequence LGETTRP inserted between positions 587 and 588 of capsid protein VP1, a nucleic acid encoding: (i) a sequence having at least 95% identity to SEQ ID NO: 9; and (ii) a sequence having at least 95% identity to SEQ ID NO: 10, and (b) a pharmaceutically acceptable excipient;
A foam dispenser, comprising: a container for holding a liquid; a pump housing connected to the container; a liquid or air chamber; a piston (122, 124) movable in the liquid or air chamber; an actuator for driving the piston; a connector (114; 314; 414) linked to the piston (122, 124) and the actuator, wherein the connector (114; 314; 414) has a flexible portion for connecting to the piston and an attachment portion (362; 462) for attaching to the actuator; characterized by a removable restrictor (208; 308; 408) for positioning between the flexible portion of the connector (114; 314; 414) and the piston (122, 124); wherein when the removable restrictor (208; 308; 408) moves the flexible portion of the connector (114; 314; 414) away from the attachment portion to allow lost motion with respect to the connector (114; 314; 414) and the pistons (122, 124); wherein movement of the connector (114; 314; 414) with the removable restrictor (208; 308; 408) in place a first distance in a first direction results in lost motion between the actuator and the piston (122, 124); and wherein continued movement of the connector (114; 314; 414) a second distance in the first direction moves the piston (122, 124) with the actuator. a container for holding a liquid; a pump housing connected to the container; a liquid or air chamber; a piston (122, 124) movable in the liquid or air chamber; an actuator for driving the piston; a connector (114; 314; 414) linked to the piston (122, 124) and the actuator, wherein the connector (114; 314; 414) has a flexible portion for connecting to the piston and an attachment portion (362; 462) for attaching to the actuator; characterized by a removable restrictor (208; 308; 408) for positioning between the flexible portion of the connector (114; 314; 414) and the piston (122, 124); wherein when the removable restrictor (208; 308; 408) moves the flexible portion of the connector (114; 314; 414) away from the attachment portion to allow lost motion with respect to the connector (114; 314; 414) and the pistons (122, 124); wherein movement of the connector (114; 314; 414) with the removable restrictor (208; 308; 408) in place a first distance in a first direction results in lost motion between the actuator and the piston (122, 124); and wherein continued movement of the connector (114; 314; 414) a second distance in the first direction moves the piston (122, 124) with the actuator.
System for taking a sample of air exhaled by a living being, said system comprising: - an inlet nozzle (IN1, IN10) through which the sample of exhaled air is injected, - an inlet valve (V1, V10) to which the inlet nozzle (IN1, IN10) is connected, - a sampling bag connected to said inlet nozzle (IN1, IN10), downstream of the inlet valve, in order to collect the sample of exhaled air, - a preconcentration device, - a transfer pipe (T1, T10) for connecting the sampling bag to the preconcentration device, - means for transferring the sample of exhaled air from said sampling bag to said preconcentration device through said transfer pipe, - a control unit configured to execute a control sequence comprising a control of said transfer means to transfer a sample from said sampling bag to said preconcentration device, the control sequence being configured to implement the following steps: - monitoring of the exhaled air in order to detect the presence of end-expiratory air; - adjustment of the inlet valve (V1, V10) to ensure the injection of end-expiratory air only to the sampling bag; - control of the transfer means to ensure a transfer of the sample of exhaled air from the sampling bag to the preconcentration device. - an inlet nozzle (IN1, IN10) through which the sample of exhaled air is injected, - an inlet valve (V1, V10) to which the inlet nozzle (IN1, IN10) is connected, - a sampling bag connected to said inlet nozzle (IN1, IN10), downstream of the inlet valve, in order to collect the sample of exhaled air, - a preconcentration device, - a transfer pipe (T1, T10) for connecting the sampling bag to the preconcentration device, - means for transferring the sample of exhaled air from said sampling bag to said preconcentration device through said transfer pipe, - a control unit configured to execute a control sequence comprising a control of said transfer means to transfer a sample from said sampling bag to said preconcentration device, - monitoring of the exhaled air in order to detect the presence of end-expiratory air; - adjustment of the inlet valve (V1, V10) to ensure the injection of end-expiratory air only to the sampling bag; - control of the transfer means to ensure a transfer of the sample of exhaled air from the sampling bag to the preconcentration device.
Proofing chamber for proofing dough, comprising - an outer frame which comprises profiled frame sections running at an angle to the gravitational direction and which encloses the interior of the proofing chamber, - a number of cover panels (3, 4, 5) which are arranged on the outer frame, - a conveyor device which runs through the interior of the proofing chamber, wherein the conveyor device is designed to transport dough pieces through the proofing chamber, and wherein the conveyor device spans a number of transport planes arranged substantially horizontally or vertically, in particular horizontally or vertically, wherein at least one profiled surface of the profiled frame sections of the outer frame which run at an angle to the gravitational direction and are arranged below the transport plane or the point of the transport plane arranged at the top in the gravitational direction is inclined in the direction of the interior, characterised in that the profiled frame sections are designed as shaping tubes and have a square or rectangular cross-section, four lengthwise edges and four lateral surfaces, wherein the outer frame is formed of shaping tubes running perpendicular and parallel to the gravitational direction and, and between the gravitational direction and the lateral surfaces of the shaping tubes inclined in the direction of the interior and running perpendicular to the gravitational direction, an angle of less than 60° is enclosed. - an outer frame which comprises profiled frame sections running at an angle to the gravitational direction and which encloses the interior of the proofing chamber, - a number of cover panels (3, 4, 5) which are arranged on the outer frame, - a conveyor device which runs through the interior of the proofing chamber, wherein the conveyor device is designed to transport dough pieces through the proofing chamber, and wherein the conveyor device spans a number of transport planes arranged substantially horizontally or vertically, in particular horizontally or vertically, wherein at least one profiled surface of the profiled frame sections of the outer frame which run at an angle to the gravitational direction and are arranged below the transport plane or the point of the transport plane arranged at the top in the gravitational direction is inclined in the direction of the interior, characterised in that the profiled frame sections are designed as shaping tubes and have a square or rectangular cross-section, four lengthwise edges and four lateral surfaces, wherein the outer frame is formed of shaping tubes running perpendicular and parallel to the gravitational direction and, and between the gravitational direction and the lateral surfaces of the shaping tubes inclined in the direction of the interior and running perpendicular to the gravitational direction, an angle of less than 60° is enclosed.
A humanized antibody or fragment for binding to CD19 comprising a heavy chain variable region sequence comprising the amino acid sequence of SEQ ID NO: 27, and a light chain variable region sequence comprising one of the amino acid sequences of SEQ ID NO: 34, SEQ ID NO: 35, or SEQ ID NO: 36.
A display apparatus, comprising: a plurality of displays (801, 802, 803) placeable in a vehicle; and a controller configured to: generate a first image having a plurality of items of first information; generate a second image having a plurality of items of second information; combine the first image and the second image to form a third image; divide the third image into a first plurality of images; and cause the plurality of displays (801, 802, 803) to respectively display one of the first plurality of images, characterized in that the controller is further configured to: receive an input for controlling a first display, among the plurality of displays (801, 802, 803), wherein the input is received when the first display is currently being booted and the input is received through a second display that has completed booting; and cause the first display to display information corresponding to the input when the first display has completed booting. a plurality of displays (801, 802, 803) placeable in a vehicle; and a controller configured to: generate a first image having a plurality of items of first information; generate a second image having a plurality of items of second information; combine the first image and the second image to form a third image; divide the third image into a first plurality of images; and cause the plurality of displays (801, 802, 803) to respectively display one of the first plurality of images, generate a first image having a plurality of items of first information; generate a second image having a plurality of items of second information; combine the first image and the second image to form a third image; divide the third image into a first plurality of images; and cause the plurality of displays (801, 802, 803) to respectively display one of the first plurality of images, characterized in that the controller is further configured to: receive an input for controlling a first display, among the plurality of displays (801, 802, 803), wherein the input is received when the first display is currently being booted and the input is received through a second display that has completed booting; and cause the first display to display information corresponding to the input when the first display has completed booting. receive an input for controlling a first display, among the plurality of displays (801, 802, 803), wherein the input is received when the first display is currently being booted and the input is received through a second display that has completed booting; and cause the first display to display information corresponding to the input when the first display has completed booting.
Household refrigeration appliance with an interior (4, 5) for receiving foodstuffs, which is delimited by walls (3a, 3b) of an inner container, and with a horizontally oriented dividing wall, which is arranged in the interior, and with a door for closing off the interior (4, 5), characterised in that the dividing wall, in a front region when viewed in the depth direction of the household refrigeration appliance, has a platform lowered downwards, wherein it has a keep-fresh container for foodstuffs arranged in the interior (4, 5), which has a drawer and a lid arranged for covering the drawer, which is mounted such that it can be raised and lowered for opening and closing the drawer in the interior (4, 5), and the dividing wall is arranged directly above the lid, and wherein it has an operating element, with which the lid can be actuated, and the operating element is arranged on the platform.
A tensioning instrument configured to apply a tensile force to a portion of an implant, the instrument comprising: a bearing member configured to abut a support surface of the implant; an actuator spaced from the bearing member in a proximal direction, the actuator including a flexible portion; and a retainer configured to attach to a portion of an implant, the retainer extending from a location on the actuator toward the bearing member, the location spaced from the bearing member a distance in the proximal direction, wherein the bearing member defines a receptacle that is sized to receive a portion of the retainer, wherein application of a force to the actuator deforms the flexible portion so as to increase the distance between the location and the bearing member, characterized in that the flexible portion includes a first actuation member and a second actuation member that is opposed to the first actuation member in a direction that is perpendicular to the proximal direction, and the retainer is disposed between the first actuation member and the second actuation member. a bearing member configured to abut a support surface of the implant; an actuator spaced from the bearing member in a proximal direction, the actuator including a flexible portion; and a retainer configured to attach to a portion of an implant, the retainer extending from a location on the actuator toward the bearing member, the location spaced from the bearing member a distance in the proximal direction, wherein the bearing member defines a receptacle that is sized to receive a portion of the retainer, wherein application of a force to the actuator deforms the flexible portion so as to increase the distance between the location and the bearing member, characterized in that the flexible portion includes a first actuation member and a second actuation member that is opposed to the first actuation member in a direction that is perpendicular to the proximal direction, and the retainer is disposed between the first actuation member and the second actuation member.
A composition for use in treating a renal disease or disorder in a subject, the use comprising administering to the subject the composition, wherein the composition comprises at least one agent, wherein the at least one agent is at least one selected from the group consisting of a renalase polypeptide fragment consisting of the amino acid sequence of SEQ ID NO: 3, and a renalase polypeptide fragment consisting of the amino acid sequence of SEQ ID NO: 4.
Wind turbine, having a pod having at least one fluid-cooled component and having a heat exchanger, wherein the heat exchanger is integrated in the outer contour of the pod, characterised in that the heat exchanger is arranged on a carrier and the carrier is constructed as a separate pod attachment piece.
An ethylene epoxidation catalyst comprising: a) a carrier comprising alumina in combination with a stability-enhancing amount of 0.5 to 20% of mullite by weight of the carrier; b) a catalytic amount of silver deposited on and/or in said carrier; and c) a promoting amount of rhenium deposited on and/or in said carrier. a) a carrier comprising alumina in combination with a stability-enhancing amount of 0.5 to 20% of mullite by weight of the carrier; b) a catalytic amount of silver deposited on and/or in said carrier; and c) a promoting amount of rhenium deposited on and/or in said carrier.
A solid state lighting lamp comprising: a plurality of heatsink modules each extending in alignment with a central axis of the lamp, each heatsink module having an outward facing surface and an inner surface opposite to the outward facing surface, and carrying a plurality of solid state lighting elements on the outward facing surface; a body extending in alignment with said central axis and delimiting an inner volume of the lamp, wherein the body is cylindrical and defines a light exit window of the solid state lighting lamp, and each heatsink module is affixed to an inner surface of said body; a base including an electrical connector; and a cap opposite said base; wherein the body and the heatsink modules extend between the base and the cap characterized in that each of the cap and the base comprises a plurality of air vents, so as to generate an air flow substantially in parallel with the central axis through the solid state lighting lamp; and in that each heatsink module is affixed to said body by at least one tongue and groove coupling (21, 41). a plurality of heatsink modules each extending in alignment with a central axis of the lamp, each heatsink module having an outward facing surface and an inner surface opposite to the outward facing surface, and carrying a plurality of solid state lighting elements on the outward facing surface; a body extending in alignment with said central axis and delimiting an inner volume of the lamp, wherein the body is cylindrical and defines a light exit window of the solid state lighting lamp, and each heatsink module is affixed to an inner surface of said body; a base including an electrical connector; and a cap opposite said base; wherein the body and the heatsink modules extend between the base and the cap characterized in that each of the cap and the base comprises a plurality of air vents, so as to generate an air flow substantially in parallel with the central axis through the solid state lighting lamp; and in that each heatsink module is affixed to said body by at least one tongue and groove coupling (21, 41).
A method for resolution enhancement of aerial images or satellite images, comprising the step of - providing at least a first two dimensional training image comprising an image of a first area on ground, wherein the 2D subimage has been captured at a first angle (α) towards the ground and at a first height above the ground, - providing a Machine Learning Network, characterized in that the method further comprises the steps of - providing a high-resolution three dimensional map created based on aerial images captured from at least two different angles, wherein the high-resolution 3D map covers a second area which at least is a part of the first area, and wherein the high-resolution 3D map has a higher resolution than the 2D training image, - extracting, from the high-resolution 3D map, a 2 dimensional submap at a second angle (β) towards the ground and at a second height above the ground, representing a third area which is at least a part of the second area and comprising geocoded 2D coordinate data and texture information, wherein the second angle (β) differs no more than 5° from the first angle (α) and wherein the second height differs no more than 5 % from the first height (hi), - extracting a 2D subimage from the 2D training image, which 2D subimage is an image of the third area, and - training the MLN, using the high-resolution 2D submap and the 2D subimage. - providing at least a first two dimensional training image comprising an image of a first area on ground, wherein the 2D subimage has been captured at a first angle (α) towards the ground and at a first height above the ground, - providing a Machine Learning Network, - providing a high-resolution three dimensional map created based on aerial images captured from at least two different angles, wherein the high-resolution 3D map covers a second area which at least is a part of the first area, and wherein the high-resolution 3D map has a higher resolution than the 2D training image, - extracting, from the high-resolution 3D map, a 2 dimensional submap at a second angle (β) towards the ground and at a second height above the ground, representing a third area which is at least a part of the second area and comprising geocoded 2D coordinate data and texture information, wherein the second angle (β) differs no more than 5° from the first angle (α) and wherein the second height differs no more than 5 % from the first height (hi), - extracting a 2D subimage from the 2D training image, which 2D subimage is an image of the third area, and - training the MLN, using the high-resolution 2D submap and the 2D subimage.