mhurhangee/ep-ind-claims huggingface dataset:
A pharmaceutical composition for use in a method of preventing or treating hypercholesterolaemia, dyslipidaemia, cardiovascular disease or cancer, in a human individual, wherein the composition is delivered by transmucosal sublingual or transmucosal buccal administration as a spray, and wherein said composition comprises: (a) a statin selected from the group consisting of simvastatin, atorvastatin, lovastatin, pitavastatin, or a salt thereof, and a carrier that comprises an oil that comprises a glyceride, wherein said statin is solubilised in said carrier; or (b) a statin selected from the group consisting of fluvastatin, pravastatin, rosuvastatin, or a salt thereof, and a carrier that comprises an aqueous solution, wherein said statin is solubilised in said carrier, and wherein the composition comprises <25%v/v ethanol, provided that if the statin is pravastatin then the composition has a pH of at least 8 and comprises <1%v/v ethanol. (a) a statin selected from the group consisting of simvastatin, atorvastatin, lovastatin, pitavastatin, or a salt thereof, and a carrier that comprises an oil that comprises a glyceride, wherein said statin is solubilised in said carrier; or (b) a statin selected from the group consisting of fluvastatin, pravastatin, rosuvastatin, or a salt thereof, and a carrier that comprises an aqueous solution, wherein said statin is solubilised in said carrier, and wherein the composition comprises <25%v/v ethanol, provided that if the statin is pravastatin then the composition has a pH of at least 8 and comprises <1%v/v ethanol.
Floor cleaning machine, in particular a hand-guided and/or hand-held floor cleaning machine, comprising a support device, at least one cleaning roller which is arranged on the support device, is capable of being driven in rotation and is provided with a cleaning substrate, a fan device for creating a suction flow, and a suction channel device for the suction flow which provides at least one suction channel operatively connected for fluid communication between the fan device and the at least one cleaning roller, wherein the at least one suction channel has at least one mouth towards the at least one cleaning roller and wherein the at least one mouth comprises a first mouth wall and a spaced second mouth wall having a mouth opening formed therebetween, wherein the first mouth wall is positioned above the second mouth wall relative to the direction of gravity (g) when the at least one cleaning roller is placed on a floor that is to be cleaned, characterized in that the first mouth wall and/or the second mouth wall is in contact against or protrudes into the cleaning substrate of the at least one cleaning roller, and in that the mouth has arranged thereat a contact element (200; 204; 216) which is in contact against or protrudes into the cleaning substrate and projects transversely away from the first mouth wall or the second mouth wall, wherein a fluid seal is present between the contact element (200; 204; 216) and the corresponding mouth wall (74; 76).
A multi-height shoe for wearing on a human foot, the shoe comprising an upper covering the foot, an insole supporting the underside of the foot while walking with the shoe, and a shoe heel raising the heel of the foot to a first height when not walking, wherein said shoe heel is constituted by a lock distinct from the insole and by a removable heel fastened to the lock and capable of being separated from the lock, wherein the upper and the insole define a fitting volume corresponding to a last adapted to a nominal heel height, wherein the insole is constituted by a front for supporting the forefoot, a camber for supporting the arch of the foot, and a seat for supporting the heel of the foot, wherein the lock extends as a platform over the entire surface of the heel seat, and wherein the front is flexible, the lock incorporating in a single piece of rigid plastics material both said platform and also a cap that extends over the entire surface of the camber, the lock being fastened to the insole over the entire surface of the heel seat and of the camber so as to make the camber undeformable while walking with the shoe for any height of removable heel that is suitable for setting said first heel height of the shoe to a value greater than said nominal height minus 25 mm and less than said nominal height plus 25 mm.
Compound of the following developed formula I: wherein: X = PO 2 R 1 =OR2; R 2 is a hydrocarbon chain of 4 to 24 carbon atoms; and n = 1. X = PO 2 R 1 =OR2; R 2 is a hydrocarbon chain of 4 to 24 carbon atoms; and n = 1.
Haptic actuator comprising: - a stator comprising at least one solenoid (110; 111, 112) capable of producing at least one electromagnetic field, the stator having a first end and a second end opposite the first end; - a movable part comprising a first surface and a second surface, the first surface extending facing the first end, the second surface extending facing the second end, the movable part being designed to be moved by the at least one electromagnetic field relative to the stator, the position of the first surface relative to the second surface being fixed when the movable part is moved; - a first return means placed between the first surface and the first end so as to return, when the movable part is moved by the at least one electromagnetic field, the movable part towards a reference position and a second return means placed between the second surface and the second end so as to return, when the movable part is moved by the at least one electromagnetic field, the movable part towards the reference position. - a stator comprising at least one solenoid (110; 111, 112) capable of producing at least one electromagnetic field, the stator having a first end and a second end opposite the first end; - a movable part comprising a first surface and a second surface, the first surface extending facing the first end, the second surface extending facing the second end, the movable part being designed to be moved by the at least one electromagnetic field relative to the stator, the position of the first surface relative to the second surface being fixed when the movable part is moved; - a first return means placed between the first surface and the first end so as to return, when the movable part is moved by the at least one electromagnetic field, the movable part towards a reference position and a second return means placed between the second surface and the second end so as to return, when the movable part is moved by the at least one electromagnetic field, the movable part towards the reference position.
A method for obtaining a liquid from a porous solid phase which has affinity for a nucleic acid or protein, which comprises: binding a nucleic acid or a protein to the porous solid phase, and releasing the nucleic acid or protein from the porous solid phase into a liquid bound to the porous solid phase; forming a liquid seal at a first end of the porous solid phase to which the liquid is bound, wherein liquid of the liquid seal is immiscible with the liquid bound to the porous solid phase; and applying a pressure differential across the porous solid phase to cause the immiscible liquid to move through the porous solid phase towards a second end of the porous solid phase, thereby displacing the liquid bound to the porous solid phase towards the second end and releasing this liquid from the second end. binding a nucleic acid or a protein to the porous solid phase, and releasing the nucleic acid or protein from the porous solid phase into a liquid bound to the porous solid phase; forming a liquid seal at a first end of the porous solid phase to which the liquid is bound, wherein liquid of the liquid seal is immiscible with the liquid bound to the porous solid phase; and applying a pressure differential across the porous solid phase to cause the immiscible liquid to move through the porous solid phase towards a second end of the porous solid phase, thereby displacing the liquid bound to the porous solid phase towards the second end and releasing this liquid from the second end.
An information processing apparatus comprising: an acquiring unit adapted to acquire a plurality of kinds of medical apparatus information, which are information acquired from a plurality of medical apparatuses; a generating unit adapted to generate information for presentation including at least a part of the plurality of kinds of medical apparatus information acquired by the acquiring unit; and a presenting unit adapted to output the generated information for presentation to an image display apparatus that displays an image, wherein the generating unit is adapted to generate the information for presentation including at least medical apparatus information acquired by a specified medical apparatus of the plurality of medical apparatuses, the presenting unit is adapted to further acquire an image in a visual field direction of the user of the image display apparatus, and the information processing apparatus further comprises a specifying unit adapted to perform image recognition of the acquired image in the visual field direction, and to specify a medical apparatus, the display unit of which is not included in the image in the visual field direction, as the specified medical apparatus. an acquiring unit adapted to acquire a plurality of kinds of medical apparatus information, which are information acquired from a plurality of medical apparatuses; a generating unit adapted to generate information for presentation including at least a part of the plurality of kinds of medical apparatus information acquired by the acquiring unit; and a presenting unit adapted to output the generated information for presentation to an image display apparatus that displays an image, wherein the generating unit is adapted to generate the information for presentation including at least medical apparatus information acquired by a specified medical apparatus of the plurality of medical apparatuses, the presenting unit is adapted to further acquire an image in a visual field direction of the user of the image display apparatus, and the information processing apparatus further comprises a specifying unit adapted to perform image recognition of the acquired image in the visual field direction, and to specify a medical apparatus, the display unit of which is not included in the image in the visual field direction, as the specified medical apparatus.
Coupling head for a coupling system, in particular for a coupling system for the pneumatic connection of a pneumatic brake system of a tractor vehicle and a trailer, with a coupling head housing, with a filter insert and with a sealing element, the coupling housing having at least one first coupling connector and at least one second coupling connector, the first coupling connector configuring a filter insert recess, into which the filter insert is inserted, and the sealing element bearing sealingly against the filter insert in the normal operating state and releasing a bypass between the sealing element and the filter insert in the bypass operating state, characterized in that the filter insert has return flow bypass openings and a diaphragm which is arranged in the interior of the filter insert and closes the return flow bypass openings sealingly in the normal operating state and releases the return flow bypass openings in a return flow bypass state.
An instrument for laser surgery, comprising: a cladding having a first refractive index; a fiber optic core coaxially disposed within the cladding and having a second refractive index that is higher than the first refractive index, the proximal end of the fiber optic core being configured to operatively engage with a source of laser energy; the distal portion of the fiber optic core defining a fiber optic tip configured to extend outwardly from the cladding; and a plurality of refracting surfaces formed in the fiber tip around a longitudinal axis of the fiber optic tip, each refracting surface being formed at least at an angle relative to the longitudinal axis and configured to disperse the laser energy in a radial pattern; wherein each one of the plurality of refracting surfaces includes a concave lens defined in the fiber optic tip. a cladding having a first refractive index; a fiber optic core coaxially disposed within the cladding and having a second refractive index that is higher than the first refractive index, the proximal end of the fiber optic core being configured to operatively engage with a source of laser energy; the distal portion of the fiber optic core defining a fiber optic tip configured to extend outwardly from the cladding; and a plurality of refracting surfaces formed in the fiber tip around a longitudinal axis of the fiber optic tip, each refracting surface being formed at least at an angle relative to the longitudinal axis and configured to disperse the laser energy in a radial pattern; wherein each one of the plurality of refracting surfaces includes a concave lens defined in the fiber optic tip.
A quantum dot LED package structure, wherein the quantum dot LED package structure comprises: a bottom bracket, an external bracket, a quantum dot layer light emitting chip, an inorganic barrier layer and a top silica gel layer; the quantum dot layer light emitting chip being provided on the bottom bracket; the external bracket being provided on the bottom bracket and surrounding the quantum dot layer light emitting chip; the inorganic barrier layer covering the external bracket and the quantum dot layer light emitting chip on the bottom bracket to package the external bracket and the quantum dot layer light emitting chip; and the top silica gel layer being provided on the inorganic barrier layer; wherein the quantum dot layer light emitting chip comprises a blue light emitting chip, a first insulation layer, a quantum dot layer, and a second insulation layer, which are provided on the bottom bracket from bottom to top in order; the quantum dot layer comprises a green quantum dot material; and the top silica gel layer is a silica gel layer comprising a KSF phosphorescent material. a bottom bracket, an external bracket, a quantum dot layer light emitting chip, an inorganic barrier layer and a top silica gel layer; the quantum dot layer light emitting chip being provided on the bottom bracket; the external bracket being provided on the bottom bracket and surrounding the quantum dot layer light emitting chip; the inorganic barrier layer covering the external bracket and the quantum dot layer light emitting chip on the bottom bracket to package the external bracket and the quantum dot layer light emitting chip; and the top silica gel layer being provided on the inorganic barrier layer; wherein the quantum dot layer light emitting chip comprises a blue light emitting chip, a first insulation layer, a quantum dot layer, and a second insulation layer, which are provided on the bottom bracket from bottom to top in order; the quantum dot layer comprises a green quantum dot material; and the top silica gel layer is a silica gel layer comprising a KSF phosphorescent material.
Yeast strain producing desmosterol, characterized in that it does not have a functional copy of the gene encoding the enzyme 24-C-methyltransferase and in that it expresses the heterologous enzyme 7-dehydrocholesterol reductase.
A method of feeding an antenna array, wherein all relative phases, normalized to a range from 0° to 360°, of consecutive 8 radiators of the array are diverse and the pattern is achieved similar to the cosecant pattern, wherein the radiators are fed as follows: - first radiator at 10°; - second radiator at 67.9°; - third radiator at 95.8°; - fourth radiator at 63.9°; - fifth radiator at 125.6°; - sixth radiator at 56.1°; - seventh radiator at 124.7°; - eighth radiator at 19.0°; wherein the radiators are preferably spaced at mutual distances of about half the transmission wavelength. - first radiator at 10°; - second radiator at 67.9°; - third radiator at 95.8°; - fourth radiator at 63.9°; - fifth radiator at 125.6°; - sixth radiator at 56.1°; - seventh radiator at 124.7°; - eighth radiator at 19.0°;
A method for performing location update by an idle mode mobile station, MS, in a wireless mobile communication system having a service area including at least one paging group in which is composed of a plurality of cells and that a paging group identifier is assigned to each of such paging groups, the method comprising the steps of: sending a request for a location update to a serving base station, BS, upon detecting a change in a paging group identifier, PG_ID; and receiving a message including a location update success notification and an allocated temporary Internet Protocol, IP, address from the serving BS in response to the request for the location update, wherein the location update success notification indicates that the MS has succeeded in the location update and an IP subnet area of the MS has changed, and comprises a first bit value in a location update response field that indicates allocation of the temporary IP address or a second bit value in the location update response field that indicates a change in the IP subnet area. sending a request for a location update to a serving base station, BS, upon detecting a change in a paging group identifier, PG_ID; and receiving a message including a location update success notification and an allocated temporary Internet Protocol, IP, address from the serving BS in response to the request for the location update, wherein the location update success notification indicates that the MS has succeeded in the location update and an IP subnet area of the MS has changed, and comprises a first bit value in a location update response field that indicates allocation of the temporary IP address or a second bit value in the location update response field that indicates a change in the IP subnet area.
A cooking system comprising: a base including a housing, the housing defining a hollow chamber configured to receive food, said housing having an upper portion defining an opening to said hollow chamber; a lid movable relative to said housing between an open position and a closed position, said lid sealing said opening to said hollow chamber in said closed position, wherein a portion of said lid is selectively positionable to form a pressure-tight heating volume between said hollow chamber and said portion of said lid; and at least one heating element (70, 74) associated with at least one of said housing and said lid, said at least one heating element (70, 74) being arranged within said pressure-tight heating volume; wherein the lid includes a lid housing and a lid lock, the lid lock being arranged within an interior of the lid housing; the lid lock including: a protrusion, and a first portion of a bayonet locking system; a second portion of the bayonet locking system extending from an upper portion of the housing; the lid lock being rotatable about an axis relative to the lid housing to engage the first portion with the second portion to lock the lid in the closed position; wherein a slot is formed at an exterior surface of the lid housing, and the protrusion is arranged within the slot to be accessible for manipulation by a user at an exterior surface of the cooking system, the lid lock being rotatable about said axis by translation of the protrusion within the slot between a first position and a second position. a base including a housing, the housing defining a hollow chamber configured to receive food, said housing having an upper portion defining an opening to said hollow chamber; a lid movable relative to said housing between an open position and a closed position, said lid sealing said opening to said hollow chamber in said closed position, wherein a portion of said lid is selectively positionable to form a pressure-tight heating volume between said hollow chamber and said portion of said lid; and at least one heating element (70, 74) associated with at least one of said housing and said lid, said at least one heating element (70, 74) being arranged within said pressure-tight heating volume; wherein the lid includes a lid housing and a lid lock, the lid lock being arranged within an interior of the lid housing; the lid lock including: a protrusion, and a first portion of a bayonet locking system; a protrusion, and a first portion of a bayonet locking system; a second portion of the bayonet locking system extending from an upper portion of the housing; the lid lock being rotatable about an axis relative to the lid housing to engage the first portion with the second portion to lock the lid in the closed position; wherein a slot is formed at an exterior surface of the lid housing, and the protrusion is arranged within the slot to be accessible for manipulation by a user at an exterior surface of the cooking system, the lid lock being rotatable about said axis by translation of the protrusion within the slot between a first position and a second position.
A method of determining the suitability of a subject to a treatment with an anti-amphiregulin antibody, wherein the subject has a cancer selected from the group consisting of ovarian cancer, head and neck cancer and pancreatic cancer exhibiting resistance to chemotherapy, the method comprising analyzing in a biological sample of the subject expression level of amphiregulin, transforming growth factor alpha (TGF-alpha) and heparin-binding epidermal growth factor (HB-EGF), wherein a level of expression of said amphiregulin above a predetermined threshold and no expression of said TGF-alpha and/or said HB-EGF or an expression below a predetermined level of said TGF-alpha and/or said HB-EGF is indicative of the suitability of the subject to treatment with said anti-amphiregulin antibody.