A compound according to Formula: wherein: X is O, S, SO, SO 2, NH, CO, CF 2, CH(CH 3), CH, or N(CH 3); Y is CH 2 or CH 2 CH 2; Z 1 is N, CH or CR 1; Z 2 is CH or CR 2; Z 3 is N, CH or CR 3; Z 4 is CH or CR 4; R 1 is fluoro or methyl; one of R 2 and R 3 is halogen, cyano, (C 1 -C 6)alkyl, halo(C 1 -C 4)alkyl, (C 1 -C 6)alkoxy, hydroxyl, B 2, -COOH, halo(C 1 -C 4)alkylC 2 -, (C 1 -C 4)alkoxy(C 1 -C 4)alkoxy, (C 1 -C 4)alkylSO 2 -, (C 1 -C 4)alkylSO 2 NHC -, (C 1 -C 4)alkylC NH-, ((C 1 -C 4)alkyl)((C 1 -C 4)alkyl)NC -, (C 1 -C 4)alkylOC -, (C 1 -C 4)alkylC N(C 1 -C 4)alkyl)-, (C 1 -C 4)alkylNHC -, (C 1 -C 4)alkoxy(C 2 -C 4)alkylNHC -, (C 1 -C 4)alkoxy(C 2 -C 4)alkylC NH-, (C 1 -C 4)alkoxy(C 2 -C 4)alkylNHC NH-, (C 1 -C 4)alkylSO 2 (C 2 -C 4)alkylNHC -, (C 1 -C 4)alkylNHC NH-, (C 1 -C 4)alkylOC NH-, hydroxy(C 1 -C 4)alkylOC NH-, 5-6 membered heterocycloalkyl-C -, 5-6 membered heterocycloalkyl-(C 1 -C 4)alkyl-NHC -, 5-6 membered heterocycloalkyl-(C 1 -C 4)alkoxy-, 5-6 membered heteroaryl, or 5-6 membered heteroaryl-C NH, wherein said 5-6 membered heterocycloalkyl and 5-6 membered heteroaryl are optionally substituted by 1 or 2 substituents each independently selected from the group consisting of (C 1 -C 4)alkyl and -(C 1 -C 4)alkyl-CN; and the other of R 2 and R 3 is halogen or (C 1 -C 6)alkyl; R 4 is fluoro, chloro, or methyl; R 5 is H or methyl; A is phenyl, 5-6 membered heteroaryl, or 5-6 membered heterocycloalkyl, wherein the carbonyl moiety and L are substituted 1,3 on ring A; m is 0 or m is 1 and R A is (C 1 -C 4)alkyl; and L is O, S, NH, N(CH 3), CH 2, CH 2 CH 2, CH(CH 3), CHF, CF 2, CH 2 O, CH 2 N(CH 3), CH 2 NH, or CH; B is an optionally substituted (C 3 -C 6)cycloalkyl, phenyl, 5-6 membered heteroaryl, or 5-6 membered heterocycloalkyl; wherein said (C 3 -C 6)cycloalkyl, phenyl, 5-6 membered heteroaryl, or 5-6 membered heterocycloalkyl is unsubstituted or is substituted by one or two substituents each independently selected from halogen, (C 1 -C 4)alkyl, halo(C 1 -C 4)alkyl, (C 1 -C 4)alkoxy, halo(C 1 -C 4)alkoxy, nitro, and (C 1 -C 4)alkylC -; or the moiety -L-B is (C 3 -C 6)alkyl, (C 3 -C 6)alkoxy, halo(C 3 -C 6)alkoxy, (C 3 -C 6)alkenyl, or (C 3 -C 6)alkenyloxy; or a salt thereof. X is O, S, SO, SO 2, NH, CO, CF 2, CH(CH 3), CH, or N(CH 3); Y is CH 2 or CH 2 CH 2; Z 1 is N, CH or CR 1; Z 2 is CH or CR 2; Z 3 is N, CH or CR 3; Z 4 is CH or CR 4; R 1 is fluoro or methyl; one of R 2 and R 3 is halogen, cyano, (C 1 -C 6)alkyl, halo(C 1 -C 4)alkyl, (C 1 -C 6)alkoxy, hydroxyl, B 2, -COOH, halo(C 1 -C 4)alkylC 2 -, (C 1 -C 4)alkoxy(C 1 -C 4)alkoxy, (C 1 -C 4)alkylSO 2 -, (C 1 -C 4)alkylSO 2 NHC -, (C 1 -C 4)alkylC NH-, ((C 1 -C 4)alkyl)((C 1 -C 4)alkyl)NC -, (C 1 -C 4)alkylOC -, (C 1 -C 4)alkylC N(C 1 -C 4)alkyl)-, (C 1 -C 4)alkylNHC -, (C 1 -C 4)alkoxy(C 2 -C 4)alkylNHC -, (C 1 -C 4)alkoxy(C 2 -C 4)alkylC NH-, (C 1 -C 4)alkoxy(C 2 -C 4)alkylNHC NH-, (C 1 -C 4)alkylSO 2 (C 2 -C 4)alkylNHC -, (C 1 -C 4)alkylNHC NH-, (C 1 -C 4)alkylOC NH-, hydroxy(C 1 -C 4)alkylOC NH-, 5-6 membered heterocycloalkyl-C -, 5-6 membered heterocycloalkyl-(C 1 -C 4)alkyl-NHC -, 5-6 membered heterocycloalkyl-(C 1 -C 4)alkoxy-, 5-6 membered heteroaryl, or 5-6 membered heteroaryl-C NH, wherein said 5-6 membered heterocycloalkyl and 5-6 membered heteroaryl are optionally substituted by 1 or 2 substituents each independently selected from the group consisting of (C 1 -C 4)alkyl and -(C 1 -C 4)alkyl-CN; and the other of R 2 and R 3 is halogen or (C 1 -C 6)alkyl; R 4 is fluoro, chloro, or methyl; R 5 is H or methyl; A is phenyl, 5-6 membered heteroaryl, or 5-6 membered heterocycloalkyl, wherein the carbonyl moiety and L are substituted 1,3 on ring A; m is 0 or m is 1 and R A is (C 1 -C 4)alkyl; and L is O, S, NH, N(CH 3), CH 2, CH 2 CH 2, CH(CH 3), CHF, CF 2, CH 2 O, CH 2 N(CH 3), CH 2 NH, or CH; B is an optionally substituted (C 3 -C 6)cycloalkyl, phenyl, 5-6 membered heteroaryl, or 5-6 membered heterocycloalkyl; wherein said (C 3 -C 6)cycloalkyl, phenyl, 5-6 membered heteroaryl, or 5-6 membered heterocycloalkyl is unsubstituted or is substituted by one or two substituents each independently selected from halogen, (C 1 -C 4)alkyl, halo(C 1 -C 4)alkyl, (C 1 -C 4)alkoxy, halo(C 1 -C 4)alkoxy, nitro, and (C 1 -C 4)alkylC -; or the moiety -L-B is (C 3 -C 6)alkyl, (C 3 -C 6)alkoxy, halo(C 3 -C 6)alkoxy, (C 3 -C 6)alkenyl, or (C 3 -C 6)alkenyloxy; or a salt thereof.