mhurhangee/ep-ind-claims huggingface dataset:
A computer implemented method for determining whether a population of human immunodeficiency virus particles has reduced susceptibility to an HIV entry inhibitor, wherein the HIV entry inhibitor is an antibody or antigen-binding fragment thereof, comprising: (a) collecting data points that measure entry of the HIV population into the cell in the presence of varying concentrations of the HIV entry inhibitor; generating a log-sigmoid inhibition curve comprising the data points showing the maximum inhibition percentage for the HIV population; and comparing this maximum inhibition percentage of the inhibition curve to the maximum inhibition percentage of a log-sigmoid inhibition curve for a reference HIV population; and determining that the HIV population has reduced susceptibility to the HIV entry inhibitor if the maximum inhibition percentage observed for the HIV population is lower than the maximum inhibition percentage observed for the reference HIV population or generating a log-sigmoid inhibition curve comprising data points for entry of the HIV in the presence of varying concentrations of the HIV entry inhibitor and determining that the HIV population has reduced susceptibility to the HIV entry inhibitor if the entry of the HIV population cannot be completely inhibited by any concentration of the HIV entry inhibitor (a) collecting data points that measure entry of the HIV population into the cell in the presence of varying concentrations of the HIV entry inhibitor; generating a log-sigmoid inhibition curve comprising the data points showing the maximum inhibition percentage for the HIV population; and comparing this maximum inhibition percentage of the inhibition curve to the maximum inhibition percentage of a log-sigmoid inhibition curve for a reference HIV population; and determining that the HIV population has reduced susceptibility to the HIV entry inhibitor if the maximum inhibition percentage observed for the HIV population is lower than the maximum inhibition percentage observed for the reference HIV population or generating a log-sigmoid inhibition curve comprising data points for entry of the HIV in the presence of varying concentrations of the HIV entry inhibitor and determining that the HIV population has reduced susceptibility to the HIV entry inhibitor if the entry of the HIV population cannot be completely inhibited by any concentration of the HIV entry inhibitor
A molding method of a molded article made of a fiber-reinforced thermoplastic resin, which obtains the fiber-reinforced thermoplastic resin by kneading a thermoplastic resin and a reinforcing fiber, and which obtains the molded article from the fiber-reinforced thermoplastic resin, the molding method comprising: a molding step comprising obtaining a primary molded article from a predetermined amount of the fiber-reinforced thermoplastic resin by a molding mold; a carrying step comprising opening the molding mold, taking out the primary molded article, and inserting the primary molded article into a cooling mold; and a compression cooling step comprising compressing and cooling the primary molded article by the cooling mold. a molding step comprising obtaining a primary molded article from a predetermined amount of the fiber-reinforced thermoplastic resin by a molding mold; a carrying step comprising opening the molding mold, taking out the primary molded article, and inserting the primary molded article into a cooling mold; and a compression cooling step comprising compressing and cooling the primary molded article by the cooling mold.
A razor assembly comprising: at least one razor blade having a cutting edge; a blade housing configured to accommodate the at least one razor blade aligned along a first direction; a connecting head configured to be detachably coupled to the blade housing; a razor handle configured to support the connecting head so that the connecting head is pivotable about a rotation axis which is perpendicular to the first direction; and a torsion spring configured to be elastically deformed when the connecting head pivots about the rotation axis from a neutral position so that the torsion spring provides a restoring force for the connecting head to return to a neutral position, a pivot member formed in the connecting head, wherein the pivot member and the torsion spring are accommodated in an accommodating space formed in the razor handle, wherein the rotation axis is perpendicular to both the first direction and a second direction in which the razor handle longitudinally extends, and wherein a central axis of the torsion spring coincides with the rotation axis, characterized in that the razor assembly further comprises an engaging tool that passes through a through-hole formed in the pivot member, the torsion spring, and at least one through-hole (33a, 33b) formed in the vicinity of the accommodating space of the razor handle at a position of the rotation axis. at least one razor blade having a cutting edge; a blade housing configured to accommodate the at least one razor blade aligned along a first direction; a connecting head configured to be detachably coupled to the blade housing; a razor handle configured to support the connecting head so that the connecting head is pivotable about a rotation axis which is perpendicular to the first direction; and a torsion spring configured to be elastically deformed when the connecting head pivots about the rotation axis from a neutral position so that the torsion spring provides a restoring force for the connecting head to return to a neutral position, a pivot member formed in the connecting head, wherein the pivot member and the torsion spring are accommodated in an accommodating space formed in the razor handle, wherein the rotation axis is perpendicular to both the first direction and a second direction in which the razor handle longitudinally extends, and wherein a central axis of the torsion spring coincides with the rotation axis, characterized in that the razor assembly further comprises an engaging tool that passes through a through-hole formed in the pivot member, the torsion spring, and at least one through-hole (33a, 33b) formed in the vicinity of the accommodating space of the razor handle at a position of the rotation axis.
A pharmaceutical composition comprising pinitol or D-chiro-inositol as an effective ingredient for use in the prevention or treatment of premenstrual syndrome.
A vehicle seat comprising: a driving portion (28, 30, 94) capable of changing a position of a seat (34, 72); a rear-seat airbag that is fixed to the seat and deploys from a seatback portion of the seat towards a rear space of the seat; characterised in that the vehicle seat further comprises a control portion (18, 66) configured to change the position of the seat with the driving portion, and adjust a deployment region of the rear-seat airbag, when a collision of a vehicle is predicted. a driving portion (28, 30, 94) capable of changing a position of a seat (34, 72); a rear-seat airbag that is fixed to the seat and deploys from a seatback portion of the seat towards a rear space of the seat; characterised in that the vehicle seat further comprises a control portion (18, 66) configured to change the position of the seat with the driving portion, and adjust a deployment region of the rear-seat airbag, when a collision of a vehicle is predicted.
A nitrided part or soft nitrided part made of a steel material comprising, by mass%, C: 0.05 to 0.3%, Si: 0.05 to 1.5%, Mn: 0.2 to 1.5%, P: 0.025% or less, S: 0.003 to 0.05%, Cr: 0.5 to 2.0%, Al: 0.01 to 0.05%, and N: 0.003 to 0.025% optionally further comprising: Mo: 0.01 to less than 0.50%, V: 0.01 to less than 0.50%, Cu: 0.01 to 0.50%, and/or Ni: 0.01 to 0.50%, and having a balance of Fe and impurities, wherein, the surface layer comprises a compound layer containing iron, nitrogen, and carbon and a nitrogen diffusion layer positioned below the compound layer, said compound layer consists of an ε single phase, said ε single phase has a thickness of 8 to 30 μm and a Vicker's hardness of 680HV or more, and said ε single phase has a volume ratio of pores of less than 10%, wherein the wear depth after application of surface pressure being 1600 MPa of repeated 2x10 6 cycles is 15 μm or less and wherein a maximum surface pressure at the fatigue limit is 1800 MPa or more, wherein the number of tests reached 10 7 without pitting occurring in the small roller test piece is defined as the fatigue limit, wherein the wear depth and the fatigue limit are determined as indicated in the description. C: 0.05 to 0.3%, Si: 0.05 to 1.5%, Mn: 0.2 to 1.5%, P: 0.025% or less, S: 0.003 to 0.05%, Cr: 0.5 to 2.0%, Al: 0.01 to 0.05%, and N: 0.003 to 0.025% Mo: 0.01 to less than 0.50%, V: 0.01 to less than 0.50%, Cu: 0.01 to 0.50%, and/or Ni: 0.01 to 0.50%, and having a balance of Fe and impurities, wherein, the surface layer comprises a compound layer containing iron, nitrogen, and carbon and a nitrogen diffusion layer positioned below the compound layer, said compound layer consists of an ε single phase, said ε single phase has a thickness of 8 to 30 μm and a Vicker's hardness of 680HV or more, and said ε single phase has a volume ratio of pores of less than 10%, having a balance of Fe and impurities, wherein, the surface layer comprises a compound layer containing iron, nitrogen, and carbon and a nitrogen diffusion layer positioned below the compound layer, said compound layer consists of an ε single phase, said ε single phase has a thickness of 8 to 30 μm and a Vicker's hardness of 680HV or more, and said ε single phase has a volume ratio of pores of less than 10%, wherein the wear depth after application of surface pressure being 1600 MPa of repeated 2x10 6 cycles is 15 μm or less and wherein a maximum surface pressure at the fatigue limit is 1800 MPa or more, wherein the number of tests reached 10 7 without pitting occurring in the small roller test piece is defined as the fatigue limit, wherein the wear depth and the fatigue limit are determined as indicated in the description.
A method for producing a potassium titanate comprising: a mixing step that mixes a titanium raw material with a potassium raw material, the titanium raw material comprising 0 to 60 mass% of titanium oxide having a specific surface area of 1 to 2 m 2 /g, 40 to 100 mass% of titanium oxide having a specific surface area of 7 to 200 m 2 /g, and 0 to 4.5 mass% in total of one or more materials selected from titanium metal and titanium hydride, and the potassium raw material comprising a potassium compound; a calcination step that calcines a raw material mixture obtained by the mixing step at a calcination temperature of 950 to 990°C; and a grinding step that grinds a calcined powder obtained by the calcination step using one or more means selected from a vibrating mill and an impact pulverizer. a mixing step that mixes a titanium raw material with a potassium raw material, the titanium raw material comprising 0 to 60 mass% of titanium oxide having a specific surface area of 1 to 2 m 2 /g, 40 to 100 mass% of titanium oxide having a specific surface area of 7 to 200 m 2 /g, and 0 to 4.5 mass% in total of one or more materials selected from titanium metal and titanium hydride, and the potassium raw material comprising a potassium compound; a calcination step that calcines a raw material mixture obtained by the mixing step at a calcination temperature of 950 to 990°C; and a grinding step that grinds a calcined powder obtained by the calcination step using one or more means selected from a vibrating mill and an impact pulverizer.
Dismantlable medical instrument with: a first component; a second component; a third component; a first bayonet connection mechanism (34, 43) for releasable mechanical connection of the third component to the second component by a first bayonet connection, a second bayonet connection mechanism (24, 42) for releasable mechanical connection of the third component to the first component by a second bayonet connection; wherein, in a first predetermined position of the third component relative to the second component, the third component is not connected to the second component, wherein, in a second predetermined position of the third component relative to the second component, the third component is mechanically connected to the second component by the first bayonet connection, and the second component and the third component are not connected to the first component, characterized in that, in a third predetermined position of the third component relative to the second component and to the first component, the third component is mechanically rigidly connected to the second component by the first bayonet connection and to the first component by the second bayonet connection, the first component having a protruding region, and the second component being substantially ring-like, the second component enclosing the protruding region on the first component when the medical instrument is assembled in the intended manner ready for operation. a first component; a second component; a third component; a first bayonet connection mechanism (34, 43) for releasable mechanical connection of the third component to the second component by a first bayonet connection, a second bayonet connection mechanism (24, 42) for releasable mechanical connection of the third component to the first component by a second bayonet connection; wherein, in a first predetermined position of the third component relative to the second component, the third component is not connected to the second component, wherein, in a second predetermined position of the third component relative to the second component, the third component is mechanically connected to the second component by the first bayonet connection, and the second component and the third component are not connected to the first component, characterized in that, in a third predetermined position of the third component relative to the second component and to the first component, the third component is mechanically rigidly connected to the second component by the first bayonet connection and to the first component by the second bayonet connection, the first component having a protruding region, and the second component being substantially ring-like, the second component enclosing the protruding region on the first component when the medical instrument is assembled in the intended manner ready for operation.
A cell based sensor that comprises: a) An hemopoyetic cell line with regulated exocytosis of secretory granules. b) Granzyme B as protease reporter transfected into the cell line of (a) that is stored into the secretory granules of such cell line. c) A transfected heterologous surface receptor used as a modulator of regulated exocytosis of the secretory granules of the cell line of (a). d) A specific substrate for detection of the secreted granule stored protease reporter or ELISA means for detecting the protease reporter. a) An hemopoyetic cell line with regulated exocytosis of secretory granules. b) Granzyme B as protease reporter transfected into the cell line of (a) that is stored into the secretory granules of such cell line. c) A transfected heterologous surface receptor used as a modulator of regulated exocytosis of the secretory granules of the cell line of (a). d) A specific substrate for detection of the secreted granule stored protease reporter or ELISA means for detecting the protease reporter.
A flush syringe assembly comprising: a barrel including a cylindrical side wall having an inside surface defining a chamber for retaining fluid, an open proximal end and a distal end including a distal wall with a tip extending distally therefrom having a passageway therethrough in fluid communication with said chamber; a plunger including an elongate body portion having a proximal end and a distal end, a stopper attached to the plunger and slidably positioned in fluid-tight engagement with said inside surface of said barrel for driving fluid out of said chamber by movement of said stopper relative to said barrel, said elongate body portion extending outwardly from said open proximal end of said barrel; said stopper including a distal end having a distal wall and a cavity therein defining an inside surface and a proximal end, characterized in that said distal wall is flexible enough to collapse at least partially into said cavity under the liquid pressure of a flush procedure and to move back toward its original shape at the completion of the flush procedure to force additional fluid into said passageway; and said inside surface of said stopper includes a proximally directed projection configured to compress when said stopper is in a collapsed position and to urge said distal wall from said collapsed position toward its original shape. a barrel including a cylindrical side wall having an inside surface defining a chamber for retaining fluid, an open proximal end and a distal end including a distal wall with a tip extending distally therefrom having a passageway therethrough in fluid communication with said chamber; a plunger including an elongate body portion having a proximal end and a distal end, a stopper attached to the plunger and slidably positioned in fluid-tight engagement with said inside surface of said barrel for driving fluid out of said chamber by movement of said stopper relative to said barrel, said elongate body portion extending outwardly from said open proximal end of said barrel; said stopper including a distal end having a distal wall and a cavity therein defining an inside surface and a proximal end, characterized in that said distal wall is flexible enough to collapse at least partially into said cavity under the liquid pressure of a flush procedure and to move back toward its original shape at the completion of the flush procedure to force additional fluid into said passageway; and said inside surface of said stopper includes a proximally directed projection configured to compress when said stopper is in a collapsed position and to urge said distal wall from said collapsed position toward its original shape.
Electronic device comprising: - a first electrode made of an inert material; - a second electrode made of a soluble material; - a solid electrolyte with an ionic conducting material base, with the first and second electrodes (103, 104) being respectively in contact with one of the faces of the electrolyte on either side of said electrolyte, with the second electrode being able to supply mobile ions circulating in the electrolyte to the first electrode in order to form a conducting filament between the first electrode and the second electrode when a voltage is applied between the first and the second electrodes; said device being characterised in that the second electrode made of a soluble material is a confinement electrode, said confinement electrode comprising an end surface in contact with the electrolyte less than the available surface of the electrolyte in such a way that a confinement is obtained of the contact zone of said confinement electrode on the solid electrolyte, and in that the volume of the electrolyte is chosen in such a way that the surface of the first end of the electrolyte in contact with the first electrode is strictly less than the surface of the second end of the electrolyte facing the first end. - a first electrode made of an inert material; - a second electrode made of a soluble material; - a solid electrolyte with an ionic conducting material base, with the first and second electrodes (103, 104) being respectively in contact with one of the faces of the electrolyte on either side of said electrolyte, with the second electrode being able to supply mobile ions circulating in the electrolyte to the first electrode in order to form a conducting filament between the first electrode and the second electrode when a voltage is applied between the first and the second electrodes;
Process for continuous extraction of impurities, in particular saponification products, from a fatty acid alkyl ester phase by mixing with a glycerol phase, characterized in that the mixed-in glycerol phase contains 5% to 40% by weight of water and citric acid as a complex former and has a pH of 3 to 6, preferably 4 to 5, wherein the aqueous glycerol phase is obtained from a source internal to the process and wherein the process is performed using an extraction column, wherein the fatty acid alkyl ester phase flows from bottom to top and in the glycerol phase in the column.
A method for wireless communication, comprising: determining a channel condition for a clear channel assessment, CCA, time duration; adjusting at least one of a transmit power or a CCA threshold level based on the determining; transmitting one or more control signals using an unadjusted transmit power; and transmitting data signals at the adjusted transmit power. determining a channel condition for a clear channel assessment, CCA, time duration; adjusting at least one of a transmit power or a CCA threshold level based on the determining; transmitting one or more control signals using an unadjusted transmit power; and transmitting data signals at the adjusted transmit power.
Device for heating, cooking and/or mixing food, comprising: a steam generator, a vessel removably closed by a lid, and in which are arranged: a removable basket with a perforated bottom to contain food to be cooked or heated, a cutting blade arranged underneath the basket, to mix the food placed in the vessel, a motor to drive the blade in rotation; the device being characterized in that: - the removable basket comprises a central steam channel, defined by an inner wall of the basket, the basket further comprising an outer wall distinct from the inner wall, - the lid comprises a radial steam channel, formed by a tube extending from a peripheral region of the lid to a central region of the lid, communicating with the central channel, to convey steam from an outlet of the steam generator towards the central steam channel, and - the lid comprises an outer wall distant from the radial channel. a steam generator, a vessel removably closed by a lid, and in which are arranged: a removable basket with a perforated bottom to contain food to be cooked or heated, a cutting blade arranged underneath the basket, to mix the food placed in the vessel, a motor to drive the blade in rotation; the device being characterized in that: - the removable basket comprises a central steam channel, defined by an inner wall of the basket, the basket further comprising an outer wall distinct from the inner wall, - the lid comprises a radial steam channel, formed by a tube extending from a peripheral region of the lid to a central region of the lid, communicating with the central channel, to convey steam from an outlet of the steam generator towards the central steam channel, and - the lid comprises an outer wall distant from the radial channel. a removable basket with a perforated bottom to contain food to be cooked or heated, a cutting blade arranged underneath the basket, to mix the food placed in the vessel, a motor to drive the blade in rotation; the device being characterized in that: - the removable basket comprises a central steam channel, defined by an inner wall of the basket, the basket further comprising an outer wall distinct from the inner wall, - the lid comprises a radial steam channel, formed by a tube extending from a peripheral region of the lid to a central region of the lid, communicating with the central channel, to convey steam from an outlet of the steam generator towards the central steam channel, and - the lid comprises an outer wall distant from the radial channel. - the removable basket comprises a central steam channel, defined by an inner wall of the basket, the basket further comprising an outer wall distinct from the inner wall, - the lid comprises a radial steam channel, formed by a tube extending from a peripheral region of the lid to a central region of the lid, communicating with the central channel, to convey steam from an outlet of the steam generator towards the central steam channel, and - the lid comprises an outer wall distant from the radial channel.