A system for analyzing image data, comprising: - an input for receiving the image data, the image data representing image intensities of an image volume, the image intensities having a signal dynamic range; - an analysis subsystem for: i) accessing display data defining a set of display settings for display of the image volume, each one of the set of display settings causing a different sub-range of the signal dynamic range to be mapped to a display dynamic range during the display, ii) analyzing the image data to identify, for each one of the set of display settings, a region of the image volume which comprises image intensities within the respective sub-range, thereby identifying a set of regions of interest (310A, 310B); and iii) generating analysis data identifying the set of regions of interest; the system being characterized by a navigation subsystem for enabling a user to navigate through the image volume by displaying different regions of the image volume in response to navigation commands received from the user, wherein the navigation subsystem is further arranged for: - enabling the user to select one of the set of display settings for displaying the different regions using said selected display setting; and - visually guiding the user towards one of the set of regions (310A, 310B) of interest which is associated with the selected display setting; wherein the navigation subsystem is arranged for visually guiding the user towards said region of interest by displaying a navigational aid which represents a navigation direction towards the region of interest. - an input for receiving the image data, the image data representing image intensities of an image volume, the image intensities having a signal dynamic range; - an analysis subsystem for: i) accessing display data defining a set of display settings for display of the image volume, each one of the set of display settings causing a different sub-range of the signal dynamic range to be mapped to a display dynamic range during the display, ii) analyzing the image data to identify, for each one of the set of display settings, a region of the image volume which comprises image intensities within the respective sub-range, thereby identifying a set of regions of interest (310A, 310B); and iii) generating analysis data identifying the set of regions of interest; the system being characterized by a navigation subsystem for enabling a user to navigate through the image volume by displaying different regions of the image volume in response to navigation commands received from the user, wherein the navigation subsystem is further arranged for: i) accessing display data defining a set of display settings for display of the image volume, each one of the set of display settings causing a different sub-range of the signal dynamic range to be mapped to a display dynamic range during the display, ii) analyzing the image data to identify, for each one of the set of display settings, a region of the image volume which comprises image intensities within the respective sub-range, thereby identifying a set of regions of interest (310A, 310B); and iii) generating analysis data identifying the set of regions of interest; the system being characterized by a navigation subsystem for enabling a user to navigate through the image volume by displaying different regions of the image volume in response to navigation commands received from the user, wherein the navigation subsystem is further arranged for: - enabling the user to select one of the set of display settings for displaying the different regions using said selected display setting; and - visually guiding the user towards one of the set of regions (310A, 310B) of interest which is associated with the selected display setting;