A compound of the Formula or a pharmaceutically acceptable salt thereof; wherein: m is an integer of 1 to 2; n is an integer of 1 to 2; o is 0; p is an integer of 0 to 5; q is an integer of 0 to 4; r is an integer of 0 to 4; s is an integer of 0 to 4; X is a nitrogen atom or CH; Y is an oxygen atom or a sulfur atom; Z 1, Z 2, Z 3, Z 4 are each independently a nitrogen atom or CH; each R 1 is independently a halogen atom, a cyano group, a C 1-6 alkyl group, a halogenated C 1-6 alkyl group, a hydroxyl C 1-6 alkyl group, a C 3-12 cycloalkyl group, a C 1-6 alkoxy group, a halogenated C 1-6 alkoxy group, a C 2-7 alkanoyl group or a group of -NR A R B., R A and R B are each independently a hydrogen atom, a C 1-6 alkyl group or a C 2-7 alkanoyl group; each R 2 is independently a hydroxyl group, a C 1-6 alkyl group, a halogenated C 1-6 alkyl group, a hydroxyl C 1-6 alkyl group, a C 1-6 alkoxy group, a halogenated C 1-6 alkoxy group, a C 6-14 aryl group, a heteroaryl group or oxo; each R 3 is independently a halogen atom, a cyano group, a C 1-6 alkyl group, a halogenated C 1-6 alkyl group, a C 3-12 cycloalkyl group, a C 1-6 alkoxy group or a halogenated C 1-6 alkoxy group; each R 4 is independently a halogen atom, a cyano group, a C 1-6 alkyl group, a C 3-12 cycloalkyl group, a halogenated C 1-6 alkyl group, a hydroxy C 1-6 alkyl group, a cyanated C 1-6 alkyl group, a C 1-6 alkoxy group, a C 1-6 alkoxy C 1-6 alkyl group, a halogenated C 1-6 alkoxy group, a C 2-7 alkanoyl group, a C 1-6 alkylthio group, a C 1-6 alkylsulfonyl group, a group of - NR A R B or oxo; a dotted line in a substructure of a bicycle represented by Formula: represents a single bond; is heteroaryl. wherein: m is an integer of 1 to 2; n is an integer of 1 to 2; o is 0; p is an integer of 0 to 5; q is an integer of 0 to 4; r is an integer of 0 to 4; s is an integer of 0 to 4; X is a nitrogen atom or CH; Y is an oxygen atom or a sulfur atom; Z 1, Z 2, Z 3, Z 4 are each independently a nitrogen atom or CH; each R 1 is independently a halogen atom, a cyano group, a C 1-6 alkyl group, a halogenated C 1-6 alkyl group, a hydroxyl C 1-6 alkyl group, a C 3-12 cycloalkyl group, a C 1-6 alkoxy group, a halogenated C 1-6 alkoxy group, a C 2-7 alkanoyl group or a group of -NR A R B., R A and R B are each independently a hydrogen atom, a C 1-6 alkyl group or a C 2-7 alkanoyl group; each R 2 is independently a hydroxyl group, a C 1-6 alkyl group, a halogenated C 1-6 alkyl group, a hydroxyl C 1-6 alkyl group, a C 1-6 alkoxy group, a halogenated C 1-6 alkoxy group, a C 6-14 aryl group, a heteroaryl group or oxo; each R 3 is independently a halogen atom, a cyano group, a C 1-6 alkyl group, a halogenated C 1-6 alkyl group, a C 3-12 cycloalkyl group, a C 1-6 alkoxy group or a halogenated C 1-6 alkoxy group; each R 4 is independently a halogen atom, a cyano group, a C 1-6 alkyl group, a C 3-12 cycloalkyl group, a halogenated C 1-6 alkyl group, a hydroxy C 1-6 alkyl group, a cyanated C 1-6 alkyl group, a C 1-6 alkoxy group, a C 1-6 alkoxy C 1-6 alkyl group, a halogenated C 1-6 alkoxy group, a C 2-7 alkanoyl group, a C 1-6 alkylthio group, a C 1-6 alkylsulfonyl group, a group of - NR A R B or oxo; a dotted line in a substructure of a bicycle represented by Formula: represents a single bond; is heteroaryl.