mhurhangee/ep-ind-claims huggingface dataset:
A recombinant adenovirus in which the proportion of the E1B-156R isoform is increased relative to the level in the equivalent wild-type adenovirus, wherein the adenovirus has an oncolytic effect in a cancer cell, and wherein the recombinant adenovirus carries a mutation in the sequence of the E1B gene of the adenovirus and the mutation in the E1B gene is A3216G wherein the numbering is relative to the adenovirus Ad5 genome (accession number AC_000008.1) (SEQ ID NO: 41) (position 1503 in the E1B gene (SEQ ID NO: 1)) or a guanine point mutation at an equivalent position to 3216 in any other adenovirus serotype.
A tire bead filler rubber composition comprising: 100 parts by mass of a solid rubber, 1 to 20 parts by mass of a modified liquid diene rubber having a functional group (a) derived from an acid anhydride, and satisfying all the requirements to below, 5 to 40 parts by mass of a phenolic resin and 0.5 to 2.0 parts by mass of a curing agent: the functional group equivalent weight of the functional groups (a) determined as set out in the description is in the range of 400 to 3,500 g/eq, the polystyrene-equivalent number average molecular weight (Mn) measured by gel permeation chromatography is in the range of 5,000 to 20,000, and the melt viscosity at 38°C is not less than 3 Pa·s and X is not less than 6100 K wherein X is the slope of a linear line passing through two points in a graph in which the two points are values of melt viscosity η (Pa·s) at 38°C and 60°C measured with a Brookfield viscometer which are plotted as Ln[η / (Pa·s)] on ordinate versus 1/T (K -1) on abscissa (with the proviso that T is temperature). 100 parts by mass of a solid rubber, 1 to 20 parts by mass of a modified liquid diene rubber having a functional group (a) derived from an acid anhydride, and satisfying all the requirements to below, 5 to 40 parts by mass of a phenolic resin and 0.5 to 2.0 parts by mass of a curing agent: the functional group equivalent weight of the functional groups (a) determined as set out in the description is in the range of 400 to 3,500 g/eq, the polystyrene-equivalent number average molecular weight (Mn) measured by gel permeation chromatography is in the range of 5,000 to 20,000, and the melt viscosity at 38°C is not less than 3 Pa·s and X is not less than 6100 K wherein X is the slope of a linear line passing through two points in a graph in which the two points are values of melt viscosity η (Pa·s) at 38°C and 60°C measured with a Brookfield viscometer which are plotted as Ln[η / (Pa·s)] on ordinate versus 1/T (K -1) on abscissa (with the proviso that T is temperature). the functional group equivalent weight of the functional groups (a) determined as set out in the description is in the range of 400 to 3,500 g/eq, the polystyrene-equivalent number average molecular weight (Mn) measured by gel permeation chromatography is in the range of 5,000 to 20,000, and the melt viscosity at 38°C is not less than 3 Pa·s and X is not less than 6100 K wherein X is the slope of a linear line passing through two points in a graph in which the two points are values of melt viscosity η (Pa·s) at 38°C and 60°C measured with a Brookfield viscometer which are plotted as Ln[η / (Pa·s)] on ordinate versus 1/T (K -1) on abscissa (with the proviso that T is temperature).
A rotor to rotate in one direction in a motor, the rotor comprising: first and second cavities (608, 618) to hold first and second permanent magnets (110a, 110b; 110d, 110e) first and second flux barriers (606, 616) to communicate with respective ends of the first and second cavities nearest to an outer circumferential surface of the rotor (104, 904); and respective ribs (352,952) formed between the outer circumferential surface of the rotor (104,904) and the first and second flux barriers (606,616) wherein a first end of each of the ribs (352,952) at an upstream side in a rotational direction of the rotor (104,904) is wider than a second end of the rib (352,952) at a downstream side in the rotational direction of the rotor (104,904), characterised in that the first and second cavities (608,618) are arranged in parallel, wherein one of the first and second cavities (608,618) is arranged to be closer to the outer circumferential surface of the rotor (104,904) than the other of the first and second cavities (608,618). first and second cavities (608, 618) to hold first and second permanent magnets (110a, 110b; 110d, 110e) first and second flux barriers (606, 616) to communicate with respective ends of the first and second cavities nearest to an outer circumferential surface of the rotor (104, 904); and respective ribs (352,952) formed between the outer circumferential surface of the rotor (104,904) and the first and second flux barriers (606,616) wherein a first end of each of the ribs (352,952) at an upstream side in a rotational direction of the rotor (104,904) is wider than a second end of the rib (352,952) at a downstream side in the rotational direction of the rotor (104,904), characterised in that the first and second cavities (608,618) are arranged in parallel, wherein one of the first and second cavities (608,618) is arranged to be closer to the outer circumferential surface of the rotor (104,904) than the other of the first and second cavities (608,618).
An optical connector cable assembly, comprising: an optical connector cable (61; 460; 661) comprising a first optical fiber extending therefrom; wherein the optical connector cable (61; 460; 661) includes a distal connector (66; 466; 666) configured to connect to a guidewire, the distal connector (66; 466; 666) comprising an inner housing (74; 474; 674) and a guidewire locking mechanism (72, 88, 90; 478, 498; 672, 698); an actuator (102; 402; 602), wherein actuation of the actuator (102; 402; 602) moves the inner housing (74; 474; 674) from a first position to a second position, wherein the actuator (102; 402; 602) comprises a sliding mechanism; wherein when the inner housing (74; 474; 674) is in the first position the guidewire locking mechanism (72, 88, 90; 478, 498; 672, 698) is configured to secure the guidewire and the guidewire is rotatable with respect to the optical connector cable (61; 460; 661); and wherein when the inner housing (74; 474; 674) is in the second position the guidewire locking mechanism (72, 88, 90; 478, 498; 672, 698) is in an open state for receiving or removing the guidewire. an optical connector cable (61; 460; 661) comprising a first optical fiber extending therefrom; wherein the optical connector cable (61; 460; 661) includes a distal connector (66; 466; 666) configured to connect to a guidewire, the distal connector (66; 466; 666) comprising an inner housing (74; 474; 674) and a guidewire locking mechanism (72, 88, 90; 478, 498; 672, 698); an actuator (102; 402; 602), wherein actuation of the actuator (102; 402; 602) moves the inner housing (74; 474; 674) from a first position to a second position, wherein the actuator (102; 402; 602) comprises a sliding mechanism; wherein when the inner housing (74; 474; 674) is in the first position the guidewire locking mechanism (72, 88, 90; 478, 498; 672, 698) is configured to secure the guidewire and the guidewire is rotatable with respect to the optical connector cable (61; 460; 661); and wherein when the inner housing (74; 474; 674) is in the second position the guidewire locking mechanism (72, 88, 90; 478, 498; 672, 698) is in an open state for receiving or removing the guidewire.
Method of in vitro diagnosis of a risk of contrast media induced nephropathy comprising the steps of i) taking a urine sample from a patient who shall become exposed to the application of contrast media; ii) assessing the level of vitamin D binding protein (VDBP) in the urine sample obtained in step (i); iii) relating the urinary vitamin D binding protein level determined in step (ii) to a pre-selected threshold level, (iv) further assessing the level of creatinine in the urine sample obtained in step (i); (v) calculating the ratio of urinary VDBP to urinary creatinine (uCr) and relating it to a pre-selected threshold level, wherein a urinary vitamin D binding protein level higher than said pre-selected threshold level and an increased VDBP/uCr ratio indicates that the patient is at risk of renal failure and in need of a dialysis treatment. i) taking a urine sample from a patient who shall become exposed to the application of contrast media; ii) assessing the level of vitamin D binding protein (VDBP) in the urine sample obtained in step (i); iii) relating the urinary vitamin D binding protein level determined in step (ii) to a pre-selected threshold level, (iv) further assessing the level of creatinine in the urine sample obtained in step (i); (v) calculating the ratio of urinary VDBP to urinary creatinine (uCr) and relating it to a pre-selected threshold level,
An atomizing assembly for an electronic cigarette, comprising: a liquid absorption element made of porous ceramic, the liquid absorption element having a liquid absorption surface configured to absorb liquid, and an atomizing surface; and a heating element configured to atomize the liquid absorbed by the liquid absorption element into atomized gas; wherein the liquid absorption element has a tubular shape, the liquid absorption element defines an atomizing passage therein, the atomizing surface is a sidewall of the atomizing passage, the liquid absorption element comprises a first layer proximately to the atomizing passage and a second layer away from the atomizing passage, the first layer has a higher thermal conductivity than a thermal conductivity of the second layer, the heating element is embedded in the first layer of the liquid absorption element. a liquid absorption element made of porous ceramic, the liquid absorption element having a liquid absorption surface configured to absorb liquid, and an atomizing surface; and a heating element configured to atomize the liquid absorbed by the liquid absorption element into atomized gas; wherein the liquid absorption element has a tubular shape, the liquid absorption element defines an atomizing passage therein, the atomizing surface is a sidewall of the atomizing passage, the liquid absorption element comprises a first layer proximately to the atomizing passage and a second layer away from the atomizing passage, the first layer has a higher thermal conductivity than a thermal conductivity of the second layer, the heating element is embedded in the first layer of the liquid absorption element.
An individual cookware control device for use on a cooktop of an induction heating cooker, comprising a casing including: - a receiver coil for sensing a time-varying electromagnetic field produced by an induction coil of the induction heating cooker, - a power supply unit for producing supply voltage, wherein the power supply unit has a rectifier and a regulator electrically connected to the receiver coil, - a temperature sensing unit having a temperature sensor for sensing a temperature of a cookware, and outputting the sensed temperature, - a user interface unit for receiving a user input and for audibly and/or visually outputting information to the user, - a control unit for controlling operation of the user interface unit and for receiving the sensed temperature output from the temperature sensing unit, wherein the casing is configured by a flat base portion having a size of a cooking zone of the cooktop, for placing the cookware thereon, and an outer portion outside the cooking zone of the cooktop which is integrally provided with the base portion, wherein the receiver coil is enclosed inside the base portion, and the user interface unit is disposed on the outer portion, wherein the temperature sensor is a contact-type temperature sensor, and the temperature sensing unit has a support means configured to movably support the temperature sensor across a predetermined range extending into the cooking zone of the cooktop, and to resiliently about the temperature sensor against a sidewall of the cookware placed in the cooking zone of the cooktop. - a receiver coil for sensing a time-varying electromagnetic field produced by an induction coil of the induction heating cooker, - a power supply unit for producing supply voltage, wherein the power supply unit has a rectifier and a regulator electrically connected to the receiver coil, - a temperature sensing unit having a temperature sensor for sensing a temperature of a cookware, and outputting the sensed temperature, - a user interface unit for receiving a user input and for audibly and/or visually outputting information to the user, - a control unit for controlling operation of the user interface unit and for receiving the sensed temperature output from the temperature sensing unit, wherein the casing is configured by a flat base portion having a size of a cooking zone of the cooktop, for placing the cookware thereon, and an outer portion outside the cooking zone of the cooktop which is integrally provided with the base portion, wherein the receiver coil is enclosed inside the base portion, and the user interface unit is disposed on the outer portion,
A pile woven fabric having a pile height equal to or less than 3mm characterized by: a loop shaped pile formed of a cotton yarn having a linear density of 118 dtex to 59 dtex (yarn count of 50-100) (both inclusive).
A method for visualizing the horizontal air permeability of the wearer-facing side of a personal hygiene article such as a diaper, the method comprising the subsequent steps of: - providing an absorbent article, extending in a longitudinal direction (y) and a transversal direction (x), wherein the article has a liquid permeable wearer-facing side and a garment-facing side; - pouring a liquid on a region of interest of the wearer-facing side of the article; - waiting for the liquid to be absorbed by the absorbent article; - applying a powder on the region of interest where the liquid was poured; - applying a testing device having a contact surface, which is preferably flat, on the region of interest on top of the powder; - optionally applying a downward force on the testing device; - forcing an air flow to circulate in the direction of the region of interest so that the powder is removed from under the contact surface of the testing device by the air flow proportionally to the horizontal air permeability of the wearer-facing side at the region of interest; - visually assessing the amount of powder removed by the airflow. - providing an absorbent article, extending in a longitudinal direction (y) and a transversal direction (x), wherein the article has a liquid permeable wearer-facing side and a garment-facing side; - pouring a liquid on a region of interest of the wearer-facing side of the article; - waiting for the liquid to be absorbed by the absorbent article; - applying a powder on the region of interest where the liquid was poured; - applying a testing device having a contact surface, which is preferably flat, on the region of interest on top of the powder; - optionally applying a downward force on the testing device; - forcing an air flow to circulate in the direction of the region of interest so that the powder is removed from under the contact surface of the testing device by the air flow proportionally to the horizontal air permeability of the wearer-facing side at the region of interest; - visually assessing the amount of powder removed by the airflow.
An irrigation process in particular for a plot of land, in which a previously established reference automatic irrigation program is modified, as a function of weather information provided by at least one weather information server, the decision to make any changes is based on at least current weather information relative to rain precipitation, characterized in that a certain number of rain precipitation situation categories are defined, comprising the "water" category assigned to at least one announcement of rain precipitation, the "lack of water" category assigned to at least one sunny weather situation, and the "uncertain" category, assigned to situations not comparable to "water" or "lack of water", the weather information relative to rain precipitation valid for the irrigation site is extracted from the received stream of weather information, and subcategories are established from the extracted meteorological information for predetermined time periods comprising the present period, the next period, and future periods, the categories assigned to those periods are stored so that they may be used as categories of previous periods, and in that the decision to modify the reference irrigation is made based on categories established by the current and future periods, then by past periods if the present and near future periods do not make it possible to make a decision.
A pharmaceutical composition for use in a method of (i) providing hematopoietic stem cells to a subject; (ii) reducing the time to engraftment following reinfusion of stem cells in a subject; (iii) reducing the incidence of delayed primary engraftment; (iv) reducing the incidence of secondary failure of platelet production; or (v) reducing the time of platelet and/or neutrophil engraftment following reinfusion of stem cells in a subject, wherein the method comprises the steps of: administering the pharmaceutical composition to a subject; enhancing the expansion of a stem cell population within bone marrow and/or mobilizing stem cells in peripheral circulation; harvesting one or more of the bone marrow stem cells or the stem cells in the peripheral circulation; and transplanting the harvested stem cells into the subject, wherein the pharmaceutical composition comprises a thrombopoietin mimetic compound of structure: wherein X 10 is a sarcosine or alanine residue; and a pharmaceutically acceptable carrier. (i) providing hematopoietic stem cells to a subject; (ii) reducing the time to engraftment following reinfusion of stem cells in a subject; (iii) reducing the incidence of delayed primary engraftment; (iv) reducing the incidence of secondary failure of platelet production; or (v) reducing the time of platelet and/or neutrophil engraftment following reinfusion of stem cells in a subject, administering the pharmaceutical composition to a subject; enhancing the expansion of a stem cell population within bone marrow and/or mobilizing stem cells in peripheral circulation; harvesting one or more of the bone marrow stem cells or the stem cells in the peripheral circulation; and transplanting the harvested stem cells into the subject, wherein the pharmaceutical composition comprises a thrombopoietin mimetic compound of structure:
A method of envelope shaping in envelope tracking power amplification, comprising: performing (310; 504) an envelope shaping operation on reference envelope signals in a time domain to obtain shaped envelope signals; the method being characterized by: converting the shaped envelope signals from the time domain to the frequency domain; performing (320; 506, 507) a signal quality control on the shaped envelope signals in a frequency domain; and converting (330; 508) the shaped envelope signals from the frequency domain into the time domain to obtain resulting shaped envelope signals. performing (310; 504) an envelope shaping operation on reference envelope signals in a time domain to obtain shaped envelope signals; the method being characterized by: converting the shaped envelope signals from the time domain to the frequency domain; performing (320; 506, 507) a signal quality control on the shaped envelope signals in a frequency domain; and converting (330; 508) the shaped envelope signals from the frequency domain into the time domain to obtain resulting shaped envelope signals. converting the shaped envelope signals from the time domain to the frequency domain; performing (320; 506, 507) a signal quality control on the shaped envelope signals in a frequency domain; and converting (330; 508) the shaped envelope signals from the frequency domain into the time domain to obtain resulting shaped envelope signals.
A computer-implemented method for instantaneous performance management of a machine tool, the method comprising: receiving, by a processing unit, real-time condition data associated with one or more components of the machine tool from one or more sources, wherein the condition data is indicative of one or more operating conditions of the machine tool in real-time; computing a dynamic stiffness value associated with one or more critical components of the machine tool which is likely to affect a performance of the machine tool based on the condition data using physics-based models; configuring a digital twin of the machine tool based on the dynamic stiffness value; simulating a behavior of the one or more critical components based on the configured digital twin in a simulation environment; predicting an impact on the performance of the machine tool based on the behavior of the one or more critical components in the simulation environment; and optimizing an operation of the machine tool based on the impact on the performance of the machine tool. receiving, by a processing unit, real-time condition data associated with one or more components of the machine tool from one or more sources, wherein the condition data is indicative of one or more operating conditions of the machine tool in real-time; computing a dynamic stiffness value associated with one or more critical components of the machine tool which is likely to affect a performance of the machine tool based on the condition data using physics-based models; configuring a digital twin of the machine tool based on the dynamic stiffness value; simulating a behavior of the one or more critical components based on the configured digital twin in a simulation environment; predicting an impact on the performance of the machine tool based on the behavior of the one or more critical components in the simulation environment; and optimizing an operation of the machine tool based on the impact on the performance of the machine tool.
Portable and measuring screwdriving tool, in particular cordless screwdriver, having an electrical drive device which generates a rotary movement, and having a first rotatable output device that is driven in rotation with respect to a first axis of rotation by the electrical drive device, wherein the tool has a second output device that is driven in rotation with respect to a second axis of rotation by the electrical drive device, and wherein the first axis of rotation and the second axis of rotation are arranged at an angle of between 30° and 90° to one another, characterized in that the tool has a switching device in order to selectively drive one of the two output devices (4, 14) by way of the drive device, wherein the tool has a first measuring device which acquires at least one first physical parameter characteristic for the output of the first output device, wherein the tool has a second measuring device which acquires at least one second physical parameter characteristic for the output of the second output device, and wherein the tool has a transmitting device for the wireless output of data to a receiving device and is set up to determine and evaluate parameters such as a torque and/or a rotational speed and/or an angle of rotation during screwdriving.