A compound having Formula (I-A) wherein R 1 denotes -(CY 2) n -E-(CY 2) n -Het 3, -(CY 2) n -Cyc-Het 3, -(CY 2) n -NHCO-Het 3, -(CY 2) n -C -(CY 2) n -Het 3, -(CY 2) n -Het 1, -(CY 2) n -NHCO-Het 1, -(CY 2) n -Ar, -(CY 2) n -C -(CY 2) n -Ar, -(CY 2) n -Cyc, -(CY 2) n -CONH-Cyc, A, -(CYR 8) n -OY, -(CY 2) n -COOY, -(CYR 8) n -CO-(CY 2) n -N(R 8) 2, -(CY 2) n -[C OH]] m -(CYR 8) n -NY 2, [-(CY 2) n -O] m -(CYR 8) n -NYCOY, -(CY 2) n -NYCOOY, -(CY 2) n -NYCON(R 8) 2, -(CY 2) n -NHCO-CH=CH 2 or -(CY 2) n -NHCO-NH-(CY 2) n =CH 2; R 3 denotes Het 1, Het 3, Ar, H, A or Cyc; R 5 denotes E-Ar, H, A, COOA or Het 1; R 8, Y denote independently from one another H or A; X denotes CO or -(CY 2) m; E denotes -(CY 2) m -, CO, -COO- or SO 2; A denotes unbranched or branched alkyl having 1-10 C atoms, in which 1-7 H atoms can be replaced independently from one another by Hal and/or OH; Cyc denotes cycloalkyl having 3-7 C atoms, in which 1-4 H atoms can be replaced independently from one another by Hal and/or OH; Ar denotes an unsaturated or aromatic mono- or bicyclic carbocycle having 5-10 C atoms, which can be substituted by at least one substituent selected from the group of A, Hal, OY, COOY, CONH 2, NHCOY, -(CH 2) n -NY 2, SO 2 NH 2, NO 2, CN and Het 2; Het 1 denotes an unsaturated or aromatic mono- or bicyclic heterocycle having 1-9 C atoms and 1-3 N, O and/or S atoms, which can be mono-or disubstituted by at least one substituent selected from the group of Hal, A, Cyc, OY, CONH 2, NHCOY, -(CH 2) n -NY 2, SO 2 NY 2, NHSO 2 Y, CN and Ar; Het 2 denotes imidazolyl, pyrazyl, thiazyl or tetrazyl, which can be monosubstituted by methyl; Het 3 denotes a saturated monocyclic heterocycle having 3-6 C atoms and 1-3 N, O and/or S atoms, which can be mono-, di- or trisubstituted by at least one substituent selected from the group of =O, A, Hal, -(CY 2) n -Cyc, -(CY 2) n -OY, COY, COOY, CONY 2, NHCOY, NY 2, CN, SO 2 Y and -(CY 2) n -Ar; Hal denotes F, Cl, Br or I; and m, n denote independently from one another 0, 1, 2 or 3; and/or a physiologically acceptable salt thereof, with the proviso that the compound 3-(3-chloro-benzoylamino)-N-[2-(2,4-dichlorophenyl)-ethyl]-4-(4-ethyl -piperazin-1-yl)-benzamide is excluded. R 1 denotes -(CY 2) n -E-(CY 2) n -Het 3, -(CY 2) n -Cyc-Het 3, -(CY 2) n -NHCO-Het 3, -(CY 2) n -C -(CY 2) n -Het 3, -(CY 2) n -Het 1, -(CY 2) n -NHCO-Het 1, -(CY 2) n -Ar, -(CY 2) n -C -(CY 2) n -Ar, -(CY 2) n -Cyc, -(CY 2) n -CONH-Cyc, A, -(CYR 8) n -OY, -(CY 2) n -COOY, -(CYR 8) n -CO-(CY 2) n -N(R 8) 2, -(CY 2) n -[C OH]] m -(CYR 8) n -NY 2, [-(CY 2) n -O] m -(CYR 8) n -NYCOY, -(CY 2) n -NYCOOY, -(CY 2) n -NYCON(R 8) 2, -(CY 2) n -NHCO-CH=CH 2 or -(CY 2) n -NHCO-NH-(CY 2) n =CH 2; R 3 denotes Het 1, Het 3, Ar, H, A or Cyc; R 5 denotes E-Ar, H, A, COOA or Het 1; R 8, Y denote independently from one another H or A; X denotes CO or -(CY 2) m; E denotes -(CY 2) m -, CO, -COO- or SO 2; A denotes unbranched or branched alkyl having 1-10 C atoms, in which 1-7 H atoms can be replaced independently from one another by Hal and/or OH; Cyc denotes cycloalkyl having 3-7 C atoms, in which 1-4 H atoms can be replaced independently from one another by Hal and/or OH; Ar denotes an unsaturated or aromatic mono- or bicyclic carbocycle having 5-10 C atoms, which can be substituted by at least one substituent selected from the group of A, Hal, OY, COOY, CONH 2, NHCOY, -(CH 2) n -NY 2, SO 2 NH 2, NO 2, CN and Het 2; Het 1 denotes an unsaturated or aromatic mono- or bicyclic heterocycle having 1-9 C atoms and 1-3 N, O and/or S atoms, which can be mono-or disubstituted by at least one substituent selected from the group of Hal, A, Cyc, OY, CONH 2, NHCOY, -(CH 2) n -NY 2, SO 2 NY 2, NHSO 2 Y, CN and Ar; Het 2 denotes imidazolyl, pyrazyl, thiazyl or tetrazyl, which can be monosubstituted by methyl; Het 3 denotes a saturated monocyclic heterocycle having 3-6 C atoms and 1-3 N, O and/or S atoms, which can be mono-, di- or trisubstituted by at least one substituent selected from the group of =O, A, Hal, -(CY 2) n -Cyc, -(CY 2) n -OY, COY, COOY, CONY 2, NHCOY, NY 2, CN, SO 2 Y and -(CY 2) n -Ar; Hal denotes F, Cl, Br or I; and m, n denote independently from one another 0, 1, 2 or 3;