mhurhangee/ep-ind-claims huggingface dataset:
A polypeptidic compound for use in prevention or treatment of cardiac remodelling in a subject, wherein said polypeptidic compound comprises the amino acid sequence set forth in SEQ ID NO: 1, or an amino acid sequence having at least 90 % sequence identity thereto, and wherein said compound comprises at least 34 amino acid residues and no more than 50 amino acid residues.
Device for sealing a motor vehicle front face air intake, comprising: ∘ a supporting frame in which is installed at least one set of flaps pivoting about pivot pins between a closed position and an open position, ∘ at least one control element configured to control the positioning of the flaps, the supporting frame including at least one row of bearings receiving the pivot pins of the flaps arranged on a side pillar, the sealing device including at least one locking element covering one row of bearings and holding the pivot pins of the flaps in said bearings, said locking element comprising a body and at least one connection member including a base connecting it to said body of the locking element and a head wider than said base, said side pillar including, on the face thereof comprising the at least one row of bearings, at least one slot opening onto an outer side of said side pillar and preferably having a shape complementing said at least one connection member, said at least one connection member being inserted into the at least one slot, and the locking element is secured to the supporting frame comprising the row of bearings by a snap fitting so as to retain the at least one connection member in the at least one slot, characterized in that the snap fitting includes a flexible tab a first end of which includes an end piece projecting towards the outside of the supporting frame and a second end of which is connected to said supporting frame, said end piece being intended for being inserted into an opening made in the locking element. ∘ a supporting frame in which is installed at least one set of flaps pivoting about pivot pins between a closed position and an open position, ∘ at least one control element configured to control the positioning of the flaps, the supporting frame including at least one row of bearings receiving the pivot pins of the flaps arranged on a side pillar, the sealing device including at least one locking element covering one row of bearings and holding the pivot pins of the flaps in said bearings, said locking element comprising a body and at least one connection member including a base connecting it to said body of the locking element and a head wider than said base, said side pillar including, on the face thereof comprising the at least one row of bearings, at least one slot opening onto an outer side of said side pillar and preferably having a shape complementing said at least one connection member, said at least one connection member being inserted into the at least one slot, and the locking element is secured to the supporting frame comprising the row of bearings by a snap fitting so as to retain the at least one connection member in the at least one slot, characterized in that the snap fitting includes a flexible tab a first end of which includes an end piece projecting towards the outside of the supporting frame and a second end of which is connected to said supporting frame, said end piece being intended for being inserted into an opening made in the locking element.
A chimeric antigen receptor characterized in that it comprises: i) one extracellular antigen recognition domain comprising a VNAR polypeptide; and ii) one transmembrane polypeptide comprising at least one signal-transducing domain; i) one extracellular antigen recognition domain comprising a VNAR polypeptide; and ii) one transmembrane polypeptide comprising at least one signal-transducing domain;
Calendar mechanism for a perpetual calendar device for timepieces, said calendar mechanism being arranged to display the duration of the current month and including a month cam whose periphery is accessible to a feeler-spindle of a perpetual calendar device for obtaining information on the duration of the current month, wherein said calendar mechanism and said month cam are arranged to be updated monthly on each current month change by a said perpetual calendar device, said month cam being generalised to an integer number of years each including a virtual 28-day month of February, and said calendar mechanism including a leap year mechanism external to said month cam, and characterized in that it is arranged to insert radially, in relation to the rotation centre of said month cam, every four years in February, a first corrector finger included in said calendar mechanism between the periphery of said month cam and a said feeler-spindle to inform the latter that the current month of February has 29 days instead of 28.
A method of inducing at least one site-directed double-strand break in chromosomal DNA of plant cells, said method comprising: (a) providing plant cells containing chromosomal double-stranded DNA, wherein said DNA comprises at least one I-Sce I restriction site; (b) transfecting said plant cells with at least a plasmid comprising DNA encoding the I-Sce I meganuclease or adding I-Sce I enzyme to said plant cells; and (c) selecting plant cells in which at least one double-strand break has been induced. (a) providing plant cells containing chromosomal double-stranded DNA, wherein said DNA comprises at least one I-Sce I restriction site; (b) transfecting said plant cells with at least a plasmid comprising DNA encoding the I-Sce I meganuclease or adding I-Sce I enzyme to said plant cells; and (c) selecting plant cells in which at least one double-strand break has been induced.
Method for processing droplets or bubbles in a microfluidic circuit comprising at least one microchannel, the microchannel being bounded by two walls (4, 8), the microchannel having a cross section perpendicular to the direction of flow of the first fluid of height (h) defined between the two walls of the microchannel, the method comprising: - making flow through the microchannel a first fluid transporting droplets or bubbles of at least one second fluid, the height (h) of the microchannel being dimensioned to squash the droplets or the bubbles during the movement thereof, - trapping at least certain of the droplets or of the bubbles in a trapping region of the microchannel placed on the path thereof, the trapping region being formed at least by a cavity produced in one of the walls of the microchannel of larger height (hc) than that of the cross section of the microchannel so as to trap said droplets or bubbles. - making flow through the microchannel a first fluid transporting droplets or bubbles of at least one second fluid, the height (h) of the microchannel being dimensioned to squash the droplets or the bubbles during the movement thereof, - trapping at least certain of the droplets or of the bubbles in a trapping region of the microchannel placed on the path thereof, the trapping region being formed at least by a cavity produced in one of the walls of the microchannel of larger height (hc) than that of the cross section of the microchannel so as to trap said droplets or bubbles.
Method for adapting at least one parameter in an open- or closed-loop-controlled system of a rail vehicle, wherein at least one position-related peripheral condition of a route network is assigned to at least some of the possible positions of the rail vehicle within the route network which can be travelled along by the vehicle, and the at least one parameter is adapted in the open- or closed-loop-controlled system of the rail vehicle during the journey as a function of the current position of the rail vehicle on the basis of the position-related peripheral condition present there, characterised in that the open- or closed-loop-controlled system comprises a device for detecting the derailing of the rail vehicle, wherein a threshold value for the triggering of a detection signal for derailing is adapted as a function of the current position of the rail vehicle.
A method for incorporating a heat stable biologically active compound for use in human or animal into a live yeast cell cultivated under aerobic conditions, comprising the following steps: a) cultivating a live yeast cell with a heat stable biologically active compound for use in human or animal, in a hormetin rich medium at a temperature comprised between 20°C and 28°C, wherein the hormetin is selected from the group consisting of a polyphenolic compound, an anthocyanin, a flavonoid, a stilbenoid, resveratrol, quercetin, fisetin, curcumin, epigallocatechin-3-gallate, caffeine, a red grape juice, a red berry juice, a pomegranate juice, a blackberry juice, a raspberry juice, a bilberry juice, a blackcurrant juice, a cranberry juice, a beetroot juice and a mixture therefore, b) increasing the temperature of the culture from the temperature in step a) to a temperature comprised between 39°C and 43°C at a rate of at least 1°C per minute; c) maintaining the temperature reached in step b) for 60 to 120 minutes; d) increasing the temperature of the culture from the temperature in step c) to a temperature comprised between 51°C and 53°C at a rate of at least 2°C per minute; e0) maintaining the temperature reached in step d) for 40 to 80 minutes; and f) isolating the live yeast cell. a) cultivating a live yeast cell with a heat stable biologically active compound for use in human or animal, in a hormetin rich medium at a temperature comprised between 20°C and 28°C, wherein the hormetin is selected from the group consisting of a polyphenolic compound, an anthocyanin, a flavonoid, a stilbenoid, resveratrol, quercetin, fisetin, curcumin, epigallocatechin-3-gallate, caffeine, a red grape juice, a red berry juice, a pomegranate juice, a blackberry juice, a raspberry juice, a bilberry juice, a blackcurrant juice, a cranberry juice, a beetroot juice and a mixture therefore, b) increasing the temperature of the culture from the temperature in step a) to a temperature comprised between 39°C and 43°C at a rate of at least 1°C per minute; c) maintaining the temperature reached in step b) for 60 to 120 minutes; d) increasing the temperature of the culture from the temperature in step c) to a temperature comprised between 51°C and 53°C at a rate of at least 2°C per minute; e0) maintaining the temperature reached in step d) for 40 to 80 minutes; and f) isolating the live yeast cell.
Door assembly comprising a door frame and a door leaf which is pivotally mounted on the door frame and can be pivoted between a closed position and an open position relative to the door frame, wherein the door leaf has a locking device for locking the door leaf to the door frame, and a drop seal having a movable sealing element for sealing a gap on the underside of the door leaf toward the floor, wherein the sealing element can be moved, by means of a drive mechanism, between a raised position and a lowered position relative to the underside of the door leaf, wherein the locking device has a drive rod and the locking device is coupled to the drop seal via the drive rod such that when the locking device is unlocked in the closed position of the door leaf, the sealing element is raised from the lowered position before the door leaf is pivoted, wherein the drive mechanism is preloaded such that the sealing element is forced into the raised position, characterized in that the drop seal is movably fastened to the underside of the door leaf so that the drop seal can be moved along the longitudinal direction of the underside of the door leaf, wherein a tappet protrudes at least partially from the end of the drop seal facing away from the drive rod, wherein the tappet comes into contact with the door frame when the door leaf is pivoted into the closed position and is subjected to a force thereby, as a result of which the tappet acts on the drive mechanism such that the sealing element is moved into the lowered position and the drop seal is preloaded in the direction of the drive rod.
A method for connecting an X-ray marker to a medical implant, comprising the steps: - providing a medical implant, the implant having an opening for receiving the X-ray marker, - providing an X-ray marker, and - gluing the X-ray marker into the opening of the medical implant by means of a liquid adhesive which comprises at least one first component comprising a fibrinogen. - providing a medical implant, the implant having an opening for receiving the X-ray marker, - providing an X-ray marker, and - gluing the X-ray marker into the opening of the medical implant by means of a liquid adhesive which comprises at least one first component comprising a fibrinogen.
Composite material with at least one support material and at least one antimicrobially effective agent from the group of the metals and metal compounds, wherein the composite material includes at least one hydrophilizing agent, which increases the wettability of the surface of the composite material with water compared to the wettability of the surface of the composite material without addition of the hydrophilizing agent, characterized in that the composite material includes at least one sulfur scavenger, wherein the mass portion of the sulfur scavenger related to the total mass of the composite material is between 0.01 % and 0.5 % and the sulfur scavenger includes a calcium, zinc, manganese, lead and/or iron compound.
A cutting guide assembly for guiding a saw blade of a cutting tool, the saw blade being configured for oscillation in a plane of oscillation around an axis of oscillation, the guide assembly comprising: a mounting block having a guide surface; a mounting arm having a first end and a second end, with a first post, having a longitudinal axis, extending from the first end in a direction substantially perpendicular to the mounting arm and configured to be retained in the mounting block in a direction perpendicular to the guide surface, and a second post extending parallel to the first post at the second end; and a cutting tool attachment component for attaching the cutting tool to the cutting guide assembly, the cutting tool attachment component having a first surface against which the saw blade can be retained for oscillation around the axis of oscillation, and a shaft, having a longitudinal axis, extending in a direction away from, and perpendicular to, the first surface and configured to cooperate with the second post such that the longitudinal axis of the shaft is collinear with the axis of oscillation of the saw blade, and such that, when the saw blade is retained against the first surface, the plane of oscillation is parallel to, and displaced from, the guide surface of the mounting block and characterised in that the mounting arm is articulated. a mounting block having a guide surface; a mounting arm having a first end and a second end, with a first post, having a longitudinal axis, extending from the first end in a direction substantially perpendicular to the mounting arm and configured to be retained in the mounting block in a direction perpendicular to the guide surface, and a second post extending parallel to the first post at the second end; and a cutting tool attachment component for attaching the cutting tool to the cutting guide assembly, the cutting tool attachment component having a first surface against which the saw blade can be retained for oscillation around the axis of oscillation, and a shaft, having a longitudinal axis, extending in a direction away from, and perpendicular to, the first surface and configured to cooperate with the second post such that the longitudinal axis of the shaft is collinear with the axis of oscillation of the saw blade, and such that, when the saw blade is retained against the first surface, the plane of oscillation is parallel to, and displaced from, the guide surface of the mounting block and characterised in that the mounting arm is articulated.
A white dry ink pulverized toner, comprising: a resin and 15% - 45% TiO2 pigment melt mixed with the resin in a twin screw extruder resulting in an extruded mix, the extruded mix being pulverized in a fluid bed jet mill and classified to a target median size of from 7 microns to 12 microns, the pulverized particles blended in a mixer with surface additives including silica, titania and zinc stearate (ZnSt), wherein the TiO2 pigment has a silica and alumina pre-treatment and a mean size of 275-325 nm, wherein the resin includes a combination of a propoxylated bisphenol-A / fumaric acid resin and a gel resin made by crosslinking the propoxylated bisphenol-A / fumaric acid resin, wherein the white dry ink pulverized toner has a developer charge between 10 and 50 μC/gram as measured according to the description and a L ∗ of at least 75 at a toner mass per unit area of less than or equal to 1.2 mg/cm 2, wherein L ∗ is measured by fusing toner layers on black substrates having a lightness (L ∗) of 5, and measuring the L ∗ of the white toner layer.
An electronic device, comprising: a panel; a display; a housing configured to support the panel; and a piezoelectric element attached to the panel, wherein the panel is deformed due to deformation of the piezoelectric element, and air conduction sound and human body vibration sound are transmitted to an object that is in contact with the deformed panel, characterised in that the display is spaced apart from the panel; the electronic device further comprises a reinforcing member disposed between the panel and the piezoelectric element, and the piezoelectric element and the reinforcing member are adhered by a first joining member, and the reinforcing member and the panel are adhered by a further joining member. a panel; a display; a housing configured to support the panel; and a piezoelectric element attached to the panel, wherein the panel is deformed due to deformation of the piezoelectric element, and air conduction sound and human body vibration sound are transmitted to an object that is in contact with the deformed panel, characterised in that the display is spaced apart from the panel; the electronic device further comprises a reinforcing member disposed between the panel and the piezoelectric element, and the piezoelectric element and the reinforcing member are adhered by a first joining member, and the reinforcing member and the panel are adhered by a further joining member.
Method for controlling the quantity of air fed into the intake of a supercharged internal combustion engine, said engine comprising two exhaust gas outlets (32, 36) each linked to an exhaust manifold (30, 34) of a group of at least one cylinder (12 1, 12 2, 12 3, 12 4), comprising a supercharging device comprising a turbocompressor with a turbine with dual intake (46, 48) connected to said exhaust gas outlets and an outside air compressor, a partial transfer duct transferring compressed air from the compressor to the intakes of the turbine, and two branches (70, 72) formed on said partial transfer duct, said branches being linked to the intakes of the turbine and each bearing valving means (74, 76), characterized in that said valving means are proportional, and in that the circulation of the compressed air in these branches during transient operating phases is controlled according to strategies applied to said valving means, and determined as a function of the characteristics of the stabilized phases, and in that the branches (70; 72) are linked by a link duct, one of the ends of the link duct being linked to the branch at a point situated between the proportional valving means and the exhaust gas outlet and the other end of the link duct being linked to the branch at a point situated between the proportional valving means and the exhaust gas outlet. in that the circulation of the compressed air in these branches during transient operating phases is controlled according to strategies applied to said valving means, and determined as a function of the characteristics of the stabilized phases, and in that the branches (70; 72) are linked by a link duct, one of the ends of the link duct being linked to the branch at a point situated between the proportional valving means and the exhaust gas outlet and the other end of the link duct being linked to the branch at a point situated between the proportional valving means and the exhaust gas outlet.
A screening device comprising a top element adapted for being mounted on or adjacent to a top frame member of a roof window, and a connection device adapted for connecting the screening device to the roof window on or adjacent to the top frame member of the roof window in such a manner that the screening device may be displaced to a position in which it forms an angle with the roof window, wherein the connection device comprises: a) at least one rod-shaped element provided on the top element and extending in a longitudinal direction of the top element, b) a receiving element adapted for being mounted on the top frame member or a side frame member (5, 6) of the roof window, and characterized in that the connection device further comprises: c) an adapter element comprising a first part adapted for locking engagement with the receiving element and a second part adapted for connection to the rod-shaped element in such a way that the second part is freely rotatable with respect to the at least one rod-shaped element at least after the first part is brought into engagement with the receiving element. a connection device adapted for connecting the screening device to the roof window on or adjacent to the top frame member of the roof window in such a manner that the screening device may be displaced to a position in which it forms an angle with the roof window, wherein the connection device comprises: a) at least one rod-shaped element provided on the top element and extending in a longitudinal direction of the top element, b) a receiving element adapted for being mounted on the top frame member or a side frame member (5, 6) of the roof window, and characterized in that the connection device further comprises: c) an adapter element comprising a first part adapted for locking engagement with the receiving element and a second part adapted for connection to the rod-shaped element in such a way that the second part is freely rotatable with respect to the at least one rod-shaped element at least after the first part is brought into engagement with the receiving element. a) at least one rod-shaped element provided on the top element and extending in a longitudinal direction of the top element, b) a receiving element adapted for being mounted on the top frame member or a side frame member (5, 6) of the roof window, and characterized in that the connection device further comprises: c) an adapter element comprising a first part adapted for locking engagement with the receiving element and a second part adapted for connection to the rod-shaped element in such a way that the second part is freely rotatable with respect to the at least one rod-shaped element at least after the first part is brought into engagement with the receiving element.