mhurhangee/ep-ind-claims huggingface dataset:
A method for the preparation of Galpβ1-4GlcNAcpβ1-3Galpβ1-4Glc (LNnT) comprising the steps of: a) reaction of a donor characterized by general formula 5 wherein R 4 is optionally substituted acyl, -NR 5 R 6 is -NH-haloacyl, X is -SR 7, wherein R 7 is selected from alkyl and optionally substituted phenyl, with an acceptor of general formula 6 wherein R 1 is a group removable by catalytic hydrogenolysis, R 2 is optionally substituted acyl and R 3 is selected from optionally substituted acyl or H, to yield a compound of general formula 4 wherein R 1, R 2, R 3, R 4 and -NR 5 R 6 are as defined above, b) converting the compound of general formula 4 into a compound of general formula 1 wherein R 1 is as defined above, c) crystallizing the compound of general formula 1, and d) subsequently subjecting the compound of general formula 1 to catalytic hydrogenolysis. a) reaction of a donor characterized by general formula 5 wherein R 4 is optionally substituted acyl, -NR 5 R 6 is -NH-haloacyl, X is -SR 7, wherein R 7 is selected from alkyl and optionally substituted phenyl, with an acceptor of general formula 6 wherein R 1 is a group removable by catalytic hydrogenolysis, R 2 is optionally substituted acyl and R 3 is selected from optionally substituted acyl or H, to yield a compound of general formula 4 wherein R 1, R 2, R 3, R 4 and -NR 5 R 6 are as defined above, wherein R 4 is optionally substituted acyl, -NR 5 R 6 is -NH-haloacyl, X is -SR 7, wherein R 7 is selected from alkyl and optionally substituted phenyl, wherein R 1 is a group removable by catalytic hydrogenolysis, R 2 is optionally substituted acyl and R 3 is selected from optionally substituted acyl or H, b) converting the compound of general formula 4 into a compound of general formula 1 wherein R 1 is as defined above, c) crystallizing the compound of general formula 1, and d) subsequently subjecting the compound of general formula 1 to catalytic hydrogenolysis.
The automatic tea maker, where the automatic coffee maker is used, comprising the containers for tea leaves and condiment products, condiment dosing device, tea leaves' dosing device with a gear, reducer of water pressure, water and vapour heaters, tea making module with thick-removal device, gear and control device of tea making module, tea release device, container of thick, control unit of machine and display with remote control, characterized in that the tea leaves' dosing device comprises two inter-touching dosing and directing discs, the dosing disc has radial grooves and is put on the gear axle, the directing disc is stationary and made concave, it has a central hole and touches with the plane of dosing disc by the circular band going around its edge, the diagonal teeth are made in the concave surface of the directing disc from the central hole to the circular band, the tea making module has position sensors (5), which are connected with the gear and control device and control unit of the machine and which may control the size of chamber of tea making module depending on the required dose of tea leaves, the volume of the chamber of tea making module is set such as to have the dose of dry tea leaves inside the chamber without any mechanical pressure.
Insulating mattress for plant components, in particular fittings, pipes and the like in shipbuilding and plant manufacture, with a thermally insulating filling and a jacket enclosing the thermally insulating filling, said jacket having an inner side facing towards the hot plant part to be insulated and an outer side facing towards the surroundings, wherein the inner side is formed from a heat-resistant fabric and the outer side is formed from a metal foil, characterised in that the outer side consists of the metal foil and an outer fabric arranged underneath the metal foil, wherein the metal foil and the outer fabric are joined to one another by joining means, namely seams, hooks and/or cramps and the heat-resistant fabric and/or the outer fabric is a metal fabric, a silicate fabric or an annealed glass fibre fabric.
A tire having a pair of shoulders and defining axial, radial, and circumferential directions, the tire comprising: a circumferential groove of radial depth H o; a plurality of axial grooves of radial depth H and circumferential width W; a plurality of shoulder blocks located circumferentially about at least one shoulder of the tire and having a height equal to radial depth H o, said shoulder blocks defined by said circumferential groove and said axial grooves, wherein said axial grooves separate adjacent said shoulder blocks, each said shoulder block having a circumferential length B, and a plurality of apertures positioned in said plurality of shoulder blocks, wherein at least one aperture is located within each said shoulder block, each said aperture having a bottom positioned at a radial depth H B relative to said shoulder block and extending completely through said shoulder block along the axial direction, each said aperture having a radial overlap H L with said axial grooves, wherein the ratio H L / H o is 0.15 or less and the ratio of H B /H is in the range of 1.0 to 1.1. a circumferential groove of radial depth H o; a plurality of axial grooves of radial depth H and circumferential width W; a plurality of shoulder blocks located circumferentially about at least one shoulder of the tire and having a height equal to radial depth H o, said shoulder blocks defined by said circumferential groove and said axial grooves, wherein said axial grooves separate adjacent said shoulder blocks, each said shoulder block having a circumferential length B, and a plurality of apertures positioned in said plurality of shoulder blocks, wherein at least one aperture is located within each said shoulder block, each said aperture having a bottom positioned at a radial depth H B relative to said shoulder block and extending completely through said shoulder block along the axial direction, each said aperture having a radial overlap H L with said axial grooves, wherein the ratio H L / H o is 0.15 or less and the ratio of H B /H is in the range of 1.0 to 1.1.
Glasses with flexible sidepiece, comprising: a frame that is separated at the bridge area, and a sidepiece that is configured from a narrow, elongated part the ends of which are coupled to articulated connection means that connect it to the respective external ends of the cited frame and which is closed at the rear of the head, characterized in that said narrow, elongated part comprises: - respective semi-rigid sections, suitable for allowing the support of the glasses on the temples of the wearer, wherein the semi-rigid sections are made of polymer plastic material, and corresponding to the two sections that include a substantially straight section of the sidepiece at their respective ends and are situated parallel to each other, corresponding to the part of the temples of the wearer when wearing the glasses; and - a flexible central area, corresponding to the rest of the part, that is, to the portion of the part that subsequently surrounds the head of the wearer, wherein said central area is made of thermoplastic elastomer material and has a higher degree of flexibility than that of the semi-rigid sections such that allows the sidepiece to be bent until the glasses can be inserted in a conventional storage bag or case, and in a way that the bent sidepiece does not protrude from the space taken up by the frame, wherein the sidepiece is configured to not lose its shape after being bent and to provide a suitable holding. - respective semi-rigid sections, suitable for allowing the support of the glasses on the temples of the wearer, wherein the semi-rigid sections are made of polymer plastic material, and corresponding to the two sections that include a substantially straight section of the sidepiece at their respective ends and are situated parallel to each other, corresponding to the part of the temples of the wearer when wearing the glasses; and - a flexible central area, corresponding to the rest of the part, that is, to the portion of the part that subsequently surrounds the head of the wearer, wherein said central area is made of thermoplastic elastomer material and has a higher degree of flexibility than that of the semi-rigid sections such that allows the sidepiece to be bent until the glasses can be inserted in a conventional storage bag or case, and in a way that the bent sidepiece does not protrude from the space taken up by the frame,
A method for the check whether a value represents a prime number, for a cryptographic application, wherein there is carried out a Fermat test (12, 26) which includes a modular exponentiation of a base with an exponent ( e) and a module ( m), wherein the exponent ( e) depends on the value to be checked and the module ( m) is identical with the value to be checked, the modular exponentiation is executed employing Montgomery operations, characterized in that the modular exponentiation is expressible as a modular exponentiation with a positive and integer exponent and a base which is a fractional value with a power of two in the denominator and the exponent ( e) of the modular exponentiation is recoded in order to obtain a recoded exponent ( f), wherein the recoded exponent ( f) is the difference of a value dependent on a Montgomery parameter and of the exponent ( e) of the modular exponentiation.
A method for predicting the responsiveness of a subject suffering from a tumor to an angiogenesis inhibitor, comprising (a) detecting the presence or absence of a mutation or loss of expression of B-Raf and the presence or absence of a mutation or loss of expression of PTEN in a sample derived from a tumor tissue of the subject, wherein in the detection step, a case where B-Raf is wild type and PTEN is wild type, or B-Raf has at least one mutation selected from Table 1 or loss of expression and PTEN has at least one mutation selected from Table 2 or loss of expression is indicative of the high responsiveness of the subject to the angiogenesis inhibitor, wherein the angiogenesis inhibitor is 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide or a pharmacologically acceptable salt thereof, and wherein the tumor is melanoma. (a) detecting the presence or absence of a mutation or loss of expression of B-Raf and the presence or absence of a mutation or loss of expression of PTEN in a sample derived from a tumor tissue of the subject, wherein in the detection step, a case where B-Raf is wild type and PTEN is wild type, or B-Raf has at least one mutation selected from Table 1 or loss of expression and PTEN has at least one mutation selected from Table 2 or loss of expression B-Raf is wild type and PTEN is wild type, or B-Raf has at least one mutation selected from Table 1 or loss of expression and PTEN has at least one mutation selected from Table 2 or loss of expression
Medical fastening device for noninvasively fastening a medical marking device (22; 124) comprising two or more marking elements (24; 128) to a body part of a patient, in particular, to a thigh, the fastening device (20; 100; 122; 130) comprising a support body which extends over a surface in two directions of extent (42, 44) aligned at an angle to each other and is adaptable in its shape to the contour of the body part, to which the marking device (22; 124) is fixed or fixable, wherein the support body is elastically stretchable in the surface of its extent and comprises a first stretch area (60; 132) and at least one second stretch area (62; 134), the stretchability of which in at least one direction (42, 44) in the surface of the extent of the support body is less than that of the first stretch area (60; 132), wherein the fastening device (20; 100) comprises at least one holding part (84; 104), which is fixed to the support body, and wherein the marking device or a marking element of the marking device is releasably fixed or fixable with force and/or positive locking on a side of the holding part (84; 104) facing away from the support body.
A system of filter escape devices, having - a filter escape device, - and also a device shell in which the filter escape device can be arranged in the resting position and which can be opened to transfer the filter escape device into a removal position, wherein the filter escape device has a hood and a filter which is integrated into the hood and has a filter inlet side and a filter outlet side, wherein the filter inlet side is closed in a gas-tight manner by a first closing element, and the filter outlet side is closed in a gas-tight manner by a second closing element, wherein arranged at at least one closing element (20, 30) there is a pulling element (1, 11) for pulling the respective closing element (20, 30) out of the filter, wherein each pulling element (1, 11) is arranged in a device shell in a resting position at a resting distance from the device shell, wherein the filter escape device can be moved into a removal position at a removal distance relative to the device shell that is increased with respect to the resting distance, wherein each pulling element (1, 11) has a first securing section (2, 12) to secure the pulling element (1, 11) to the closing element (20, 30) and a second securing section (3, 13) for securement to an inner side (110, 120) of the device shell, wherein the two securing sections (2, 3; 12, 13) are at a securing distance from each other that is smaller than or equal to the removal distance, wherein arranged, furthermore, on the inner side (110, 120) of the device shell there is at least one pulling-element holding arrangement (111, 121) for securement of the second securing section of at least one pulling element (1, 11), and wherein the at least one pulling element (1, 11) and the at least one pulling-element holding arrangement are formed and matched to each other in such a way that when the device shell is opened, upon attainment of the removal distance between the device shell and the filter escape device, the at least one closing element (20, 30) is automatically pulled out of the filter. - a filter escape device, - and also a device shell in which the filter escape device can be arranged in the resting position and which can be opened to transfer the filter escape device into a removal position,
A hybrid power generation system using a supercritical CO 2 cycle, comprising a steam power generation unit comprising a plurality of turbines driven with steam heated by a boiler to produce electric power, for producing electric power using a supercritical CO 2 fluid, the hybrid power generation system comprising: a supercritical CO 2 power generation unit comprising an S-CO 2 heater for heating the supercritical CO 2 fluid, a turbine driven by the supercritical CO 2 fluid, a precooler for lowering a temperature of the supercritical CO 2 fluid passing through the turbine, and a main compressor for pressurizing the supercritical CO 2 fluid, so as to produce electric power, and characterized in that the steam power generation unit and the supercritical CO 2 power generation unit share the boiler. a supercritical CO 2 power generation unit comprising an S-CO 2 heater for heating the supercritical CO 2 fluid, a turbine driven by the supercritical CO 2 fluid, a precooler for lowering a temperature of the supercritical CO 2 fluid passing through the turbine, and a main compressor for pressurizing the supercritical CO 2 fluid, so as to produce electric power, and characterized in that the steam power generation unit and the supercritical CO 2 power generation unit share the boiler.
Spraying device for mixtures obtained from the reaction of polymer materials, comprising: - a casing which encloses at least one mixing chamber and which is provided at one of its ends with a nozzle; - a mixer which extends at least partially inside the mixing chamber along a longitudinal axis of said mixing chamber and which is designed to rotate about said longitudinal axis; the mixer being intended to mix together at least two reactive polymer components introduced inside the mixing chamber so as to obtain a polymer mixture; said polymer mixture being suitable for being sprayed through the nozzle in the form of a spray cone, characterized in that the mixer is provided with an appendix which protrudes, at least partially, from the casing through the nozzle; said appendix being provided with a deviation surface, on the outside of the nozzle, which is inclined at an angle of deviation (α) relative to the longitudinal axis and which is intended to intercept and to deviate at least a first portion of the spray cone sprayed through the nozzle. - a casing which encloses at least one mixing chamber and which is provided at one of its ends with a nozzle; - a mixer which extends at least partially inside the mixing chamber along a longitudinal axis of said mixing chamber and which is designed to rotate about said longitudinal axis; the mixer being intended to mix together at least two reactive polymer components introduced inside the mixing chamber so as to obtain a polymer mixture; said polymer mixture being suitable for being sprayed through the nozzle in the form of a spray cone,
Mixer for an exhaust gas system of a combustion engine for mixing a reactant with an exhaust gas flow, - with a pipe portion, enclosing a flow cross-section through which the exhaust gas flow may circulate in a circumferential direction and extending in an axial direction from a first axial side of the pipe portion to a second axial side of the pipe portion, - with several guide blades (14, 15), each having an angle of attack (29, 30) in relation to the axial direction, projecting from the pipe portion at least at one axial side (19, 20) so that they project into the flow cross section, wherein the guide blades (14, 15) are at least divided into a first guide blade group and a second guide blade group and wherein the guide blades of the first guide blade group are arranged axially offset to the guide blades of the second guide blade group, wherein the angles of attack of the guide blades of the first guide blade group are oriented opposed to the angles of attack of the guide blades of the second guide blade group, characterized in that the first guide blade group and the second guide blade group are adjacent to another succeeding each other in the circumferential direction, so that each guide blade group (21, 22) extends only across part of the circumference of the pipe portion and so that the two guide blade groups (21, 22) do not overlap each other in the axial direction. - with a pipe portion, enclosing a flow cross-section through which the exhaust gas flow may circulate in a circumferential direction and extending in an axial direction from a first axial side of the pipe portion to a second axial side of the pipe portion, - with several guide blades (14, 15), each having an angle of attack (29, 30) in relation to the axial direction, projecting from the pipe portion at least at one axial side (19, 20) so that they project into the flow cross section, wherein the guide blades (14, 15) are at least divided into a first guide blade group and a second guide blade group and wherein the guide blades of the first guide blade group are arranged axially offset to the guide blades of the second guide blade group,
Container for medical or diagnostic use, intended to hold a product of interest, in divided or undivided solid, gel, powder or liquid form, at least one wall of the said container being provided with at least one three-dimensional marking zone in which at least one identification code, is in positive or negative form, and integrated into said wall, is reproduced so as to be readable, wherein the identification code is reproduced by illumination of the said marking zone with at least one beam of coherent monochromatic localized electromagnetic radiation to which the substrate is at least partially transparent, the beam removing or modifying the constituent substrate, characterized in that the differences in internal tension in said wall between the marking zone and the rest of the wall are reduced by annealing the at least one marking zone to a second temperature above a first temperature, wherein the impact strength of the container thus marked is not affected, wherein the container is made of glass or plastic, and wherein the device is closed off by means for at least partly ensuring the integrity of the contents, the said means defining at least two end sealing zones (12a, 12b), which seal against the wall of the container, and leaving a gap between them, wherein the length, or height, of the marking zone along the axis of the container is less than the distance (d) separating the two end sealing zones (12a, 12b) that define the said gap.
Arrangement comprising a processing unit for manufacturing or processing a semi-finished product produced from round timber and machined on four sides, a measuring device for determining a curvature of the semi-finished product in a plane of curvature, and a transport unit for transporting the semi-finished product through the measuring device along a transport direction, wherein the measuring device has at least three measurement planes (a, b, c) arranged one after the other and - the measuring device is arranged so closely after the processing unit in the transport direction that during transport of the semi-finished product through the measuring device measurement is already being made at the forward end of the semi-finished product in the transport direction while processing by means of the processing unit is still taking place at the rear end of the semi-finished product or - the measuring device is arranged so closely before the processing unit in the transport direction that during transport of the semi-finished product through the measuring device measurement is still being made at the rear end of the semi-finished product in the transport direction while processing by means of the processing unit is already taking place at the forward end of the semi-finished product, characterised in that the arrangement further comprises a saw and is constructed in such a way that the curvature determined by means of the measuring device is taken into account in guidance of a cutting operation in that the semi-finished product is guided through the saw so as to follow a curve along the measured line of curvature or, during passage of the semi-finished product, saw blades of the saw are appropriately positioned and guided so as to follow the curved shape. - the measuring device is arranged so closely after the processing unit in the transport direction that during transport of the semi-finished product through the measuring device measurement is already being made at the forward end of the semi-finished product in the transport direction while processing by means of the processing unit is still taking place at the rear end of the semi-finished product or - the measuring device is arranged so closely before the processing unit in the transport direction that during transport of the semi-finished product through the measuring device measurement is still being made at the rear end of the semi-finished product in the transport direction while processing by means of the processing unit is already taking place at the forward end of the semi-finished product,