Breaker device for acting onto a closure element of a medical tubing, comprising: - a drive arrangement having a drive device, a drive element driven by the drive device and at least one locking element (22A, 22B), and - a breaker module which is arrangeable on the drive arrangement, the breaker module comprising a housing, a movable part movably arranged on the housing, a breaking element for acting onto the closure element of the tubing and a locking mechanism (32A, 32B), wherein the breaker module in an attached state is placed on the drive arrangement and is locked to the drive arrangement via the locking mechanism (32A, 32B) engaging with the at least one locking element (22A, 22B), the drive element being in operative connection with the movable part in the attached state such that a movement of the drive element causes the movable part to move for actuating the breaking element, wherein the breaker module is releasable from the drive arrangement by disengaging the locking mechanism (32A, 32B) from the at least one locking element (22A, 22B), characterized in that the locking mechanism comprises at least one actuation member (32A, 32B) which comprises a head section facing an engagement section (313, 314) of the movable part and which comprises an engagement opening and which is displaceable between a first position and a second position with respect to the housing, wherein the at least one actuation member (32A, 32B) is constituted - to act, in the first position, onto the movable part, with the head section engaging with the engagement section (313, 314), to hold the movable part in a predefined position for establishing the operative connection with the drive element that assumes a default position when arranging the breaker module on the drive arrangement, and - to establish a locking engagement, with the at least one locking element (22A, 22B) reaching through the engagement opening of the at least one actuation member (32A, 32B), when the at least one actuation member (32A, 32B) is displaced from the first into the second positon, with the at least one locking element (22A, 22B) of the drive arrangement, such that in the second position the breaker module is locked relative to the drive arrangement when the breaker module is in the attached state. - a drive arrangement having a drive device, a drive element driven by the drive device and at least one locking element (22A, 22B), and - a breaker module which is arrangeable on the drive arrangement, the breaker module comprising a housing, a movable part movably arranged on the housing, a breaking element for acting onto the closure element of the tubing and a locking mechanism (32A, 32B), wherein the breaker module in an attached state is placed on the drive arrangement and is locked to the drive arrangement via the locking mechanism (32A, 32B) engaging with the at least one locking element (22A, 22B), the drive element being in operative connection with the movable part in the attached state such that a movement of the drive element causes the movable part to move for actuating the breaking element, wherein the breaker module is releasable from the drive arrangement by disengaging the locking mechanism (32A, 32B) from the at least one locking element (22A, 22B), characterized in that the locking mechanism comprises at least one actuation member (32A, 32B) which comprises a head section facing an engagement section (313, 314) of the movable part and which comprises an engagement opening and which is displaceable between a first position and a second position with respect to the housing, wherein the at least one actuation member (32A, 32B) is constituted - to act, in the first position, onto the movable part, with the head section engaging with the engagement section (313, 314), to hold the movable part in a predefined position for establishing the operative connection with the drive element that assumes a default position when arranging the breaker module on the drive arrangement, and - to establish a locking engagement, with the at least one locking element (22A, 22B) reaching through the engagement opening of the at least one actuation member (32A, 32B), when the at least one actuation member (32A, 32B) is displaced from the first into the second positon, with the at least one locking element (22A, 22B) of the drive arrangement, such that in the second position the breaker module is locked relative to the drive arrangement when the breaker module is in the attached state.