mhurhangee/ep-ind-claims huggingface dataset:
A mutant reverse transcriptase with increased thermal stability relative to the wildtype RT of SEQ ID NO: 1, the mutant RT comprising i) an amino acid sequence that has six amino acid substitutions relative to wildtype RT of SEQ ID NO: 1, wherein - Ala at position 32 is substituted with Val (A32V); - Leu at position 72 is substituted with Arg (L72R); - Glu at position 286 is substituted with Arg (E286R); - Glu at position 302 is substituted with Lys (E302K); - Trp at position 388 is substituted with Arg (W388R); and - Leu at position 435 is substituted with Arg (L435R), or ii) an amino acid sequence that is at least 95 % identical to the amino acid sequence of i) and has the six amino acid substitutions as defined in i), wherein the mutant RT exhibits reverse transcriptase activity and wherein the mutant RT has an increased thermal stability relative to mutant MM3, wherein MM3 has an amino acid sequence that differs from the one of SEQ ID NO: 1 only by three amino acid substitutions, wherein Glu at position 286 is substituted with Arg (E286R), Glu at position 302 is substituted with Lys (E302K) and Leu at position 435 is substituted with Arg (L435R). i) an amino acid sequence that has six amino acid substitutions relative to wildtype RT of SEQ ID NO: 1, wherein - Ala at position 32 is substituted with Val (A32V); - Leu at position 72 is substituted with Arg (L72R); - Glu at position 286 is substituted with Arg (E286R); - Glu at position 302 is substituted with Lys (E302K); - Trp at position 388 is substituted with Arg (W388R); and - Leu at position 435 is substituted with Arg (L435R), or - Ala at position 32 is substituted with Val (A32V); - Leu at position 72 is substituted with Arg (L72R); - Glu at position 286 is substituted with Arg (E286R); - Glu at position 302 is substituted with Lys (E302K); - Trp at position 388 is substituted with Arg (W388R); and - Leu at position 435 is substituted with Arg (L435R), or ii) an amino acid sequence that is at least 95 % identical to the amino acid sequence of i) and has the six amino acid substitutions as defined in i),
Tool for the production of industrial parts, constituted by a housing (1,1') constituted by a frame (2,2') to which is removably fixed a cassette (3, 3a - 3', 3'a), said cassette constituting the actual tool, the cassette (3, 3a - 3', 3'a) comprising centring columns, intended to be engaged in corresponding receiving holes made on the front face of the frame, characterised in that the centring columns comprise a conical peripheral projection intended to come into contact with a corresponding radiused part formed on the receiving face of a deformable centring washer arranged at the entrance of the receiving holes, while the receiving holes of the centring columns have a diameter slightly greater than the diameter of the centring columns, so as to achieve a perfect position of the cassette on its frame.
A detonator block for housing a detonator, the detonator block comprising: a detonator; a body configured to host the detonator; the body having a first end that is configured to be attached to a sub; the body having a second end, opposite to the first end, and configured to electrically connect to a gun; a printed circuit board located inside the body, the printed circuit board being electrically connected to the detonator, and wherein the printed circuit board is shaped to extend around the detonator; and plural electrical contacts (246A, 246B) electrically connected to the printed circuity board, each electrical contact being a spring loaded contact having a respective pin that extends outside the body, at the second end, wherein one of the plural electrical contacts is connected to a ground line, and another one of the plural electrical contacts is connected to a through line. a detonator; a body configured to host the detonator; the body having a first end that is configured to be attached to a sub; the body having a second end, opposite to the first end, and configured to electrically connect to a gun; a printed circuit board located inside the body, the printed circuit board being electrically connected to the detonator, and wherein the printed circuit board is shaped to extend around the detonator; and plural electrical contacts (246A, 246B) electrically connected to the printed circuity board, each electrical contact being a spring loaded contact having a respective pin that extends outside the body, at the second end, wherein one of the plural electrical contacts is connected to a ground line, and another one of the plural electrical contacts is connected to a through line.
A method by a user equipment, the method comprising: initiating, by the user equipment, a browser of the user equipment; obtaining (381, 389), by the user equipment, proxy information corresponding to the browser based on public land mobile network, PLMN, identification information of the user equipment from a network entity, wherein the network entity is also for obtaining information related to a traffic requested from the browser, setting, by the user equipment, a proxy to be used by the browser based on the obtained proxy information; and transmitting by the user equipment, the traffic that is requested from the browser through the set proxy.
An infusion pump device, comprising: a pump housing that defines a space to receive a medicine cartridge; a drive system to dispense a medicine from the medicine cartridge when the medicine cartridge is received by the pump housing; and a cap device that engages the pump housing to retain the medicine cartridge therein when the medicine cartridge is received by the pump housing, the cap device comprising a needle device that penetrates an output portion of the medicine cartridge when the cap device engages the pump housing, wherein when the cap device engages the pump housing, the cap device acts upon the medicine cartridge to urge a plunger of the medicine cartridge to engage a component of the drive system, and wherein when the cap device engages the pump housing, the cap device acts upon the medicine cartridge to urge an initial breakaway movement of the plunger inside the medicine cartridge, characterised in that the drive system comprises a piston rod having a plunger engagement device (375, 380) that secures to the plunger of the medicine cartridge when the medicine cartridge is received by the pump housing. a pump housing that defines a space to receive a medicine cartridge; a drive system to dispense a medicine from the medicine cartridge when the medicine cartridge is received by the pump housing; and a cap device that engages the pump housing to retain the medicine cartridge therein when the medicine cartridge is received by the pump housing, the cap device comprising a needle device that penetrates an output portion of the medicine cartridge when the cap device engages the pump housing, wherein when the cap device engages the pump housing, the cap device acts upon the medicine cartridge to urge a plunger of the medicine cartridge to engage a component of the drive system, and wherein when the cap device engages the pump housing, the cap device acts upon the medicine cartridge to urge an initial breakaway movement of the plunger inside the medicine cartridge, characterised in that the drive system comprises a piston rod having a plunger engagement device (375, 380) that secures to the plunger of the medicine cartridge when the medicine cartridge is received by the pump housing.
A curable composition comprising from 70 to 99% by dry weight based on total dry weight of the curable composition, an acrylic emulsion component, and from 1 to 30% by dry weight based on the total dry weight of the curable composition, a polyolefin emulsion component prepared by emulsifying a polycarboxylic-compound functionalized polyolefin starting material; wherein the polyolefin starting material is selected from the group consisting of thermally degraded homopolymers and copolymers of ethylene, propylene, 1-butene, 4-methyl-1-pentene, 3-methyl-1-butene, 4,4-dimethyl-1-pentene, 3-methyl-1-pentene, 4-methyl-1-hexene, 5-ethyl-1-hexene, 6-methyl-1-heptene, 1-hexene, 1-heptene, 1-octene, 1-nonene, and 1-decene.
An electromagnetic heating control circuit, comprising: a control chip, a rectifying and filtering circuit, a resonance capacitor, a switch transistor, a drive circuit, and a synchronous voltage detection circuit, wherein, the switch transistor comprises a first terminal, a second terminal, and a control terminal configured to control a connected state between the first terminal and the second terminal, the first terminal is connected to a positive output terminal of the rectifying and filtering circuit via the resonance capacitor, the second terminal is connected to a negative output terminal of the rectifying and filtering circuit via a current-limiting resistor; the electromagnetic heating control circuit being characterized in that the control chip comprises a non-inverting voltage input terminal, an inverting voltage input terminal, a voltage detection terminal, and a signal output terminal, the non-inverting voltage input terminal and the inverting voltage input terminal detect voltages at two terminals of the resonance capacitor via the synchronous voltage detection circuit, the signal output terminal is connected to the control terminal via the drive circuit, the voltage detection terminal is connected to the positive output terminal of the rectifying and filtering circuit via the synchronous voltage detection circuit, the control chip is configured to control a work state of the switch transistor according to a voltage detected by the voltage detection terminal, and to control, according to voltages of the non-inverting voltage input terminal and the inverting voltage input terminal, the switch transistor to turn on when a voltage at a connection node between the resonance capacitor and the switch transistor is zero.
A method for resource management of cloud resources, comprising the steps of: slicing resources provided by an infrastructure provider comprising a computation node, a control apparatus and a resource policy database; and assigning the sliced resources to different clouds according to predetermined cloud resource policies of the respective clouds, each of the clouds comprising at least one control node; sending, by the control node of the respective cloud, a resource inquiry, RINQ, for available resources of the infrastructure provider to the computation node; forwarding, by the computation node of the infrastructure provider, the received RINQ to a resource broker of the control apparatus which reads the cloud resource policy of the respective cloud from the resource policy database; and sending, by the resource broker, a resource response message, RRMSG, indicating resources of the infrastructure provider which are available and which have been verified by the resource broker of the infrastructure provider to the computation node of the infrastructure provider having received the RINQ from the inquiring control node of the respective cloud. slicing resources provided by an infrastructure provider comprising a computation node, a control apparatus and a resource policy database; and assigning the sliced resources to different clouds according to predetermined cloud resource policies of the respective clouds, each of the clouds comprising at least one control node; sending, by the control node of the respective cloud, a resource inquiry, RINQ, for available resources of the infrastructure provider to the computation node; forwarding, by the computation node of the infrastructure provider, the received RINQ to a resource broker of the control apparatus which reads the cloud resource policy of the respective cloud from the resource policy database; and sending, by the resource broker, a resource response message, RRMSG, indicating resources of the infrastructure provider which are available and which have been verified by the resource broker of the infrastructure provider to the computation node of the infrastructure provider having received the RINQ from the inquiring control node of the respective cloud.
A method for assisting aircraft guidance, the method being operated by a computation platform for aircraft and comprising at least: - a step of acquisition of state variables characterising an aircraft in flight, of environment variables characterising the environment of the aircraft and of trajectory variables characterising a reference trajectory of the aircraft; characterised in that the method further comprises: - a step of calculation of a predicted real trajectory consisting in calculating prediction variables from said state variables, environment variables and reference trajectory variables, the prediction variables characterising the prediction of a real roll and/or of a real position of the aircraft for an upcoming change of direction of the aircraft; - a step of determination of conformity to determine whether the predicted real trajectory which is calculated conforms to the reference trajectory; and - if the predicted real trajectory does not conform to the reference trajectory, a step of configuration of a trajectory deviation alert informing of the roll and/or of the lateral deviation of the aircraft with respect to the reference trajectory on the upcoming change of direction. - a step of acquisition of state variables characterising an aircraft in flight, of environment variables characterising the environment of the aircraft and of trajectory variables characterising a reference trajectory of the aircraft; - a step of calculation of a predicted real trajectory consisting in calculating prediction variables from said state variables, environment variables and reference trajectory variables, the prediction variables characterising the prediction of a real roll and/or of a real position of the aircraft for an upcoming change of direction of the aircraft; - a step of determination of conformity to determine whether the predicted real trajectory which is calculated conforms to the reference trajectory; and - if the predicted real trajectory does not conform to the reference trajectory, a step of configuration of a trajectory deviation alert informing of the roll and/or of the lateral deviation of the aircraft with respect to the reference trajectory on the upcoming change of direction.
Variable displacement lubricant pump for providing pressurized lubricant for an internal combustion engine, whereby a pump rotor with several slidable vanes rotating in a shiftable control ring is provided, the control ring being actuated by a hydraulic control chamber directly actuating the control ring, whereby a temperature control opening is provided in a control chamber wall, the variable displacement lubricant pump being characterised in that a temperature control valve is provided to connect or disconnect the temperature control opening to atmospheric pressure, and the temperature control valve is provided with a switching strip with a switching temperature T s, the switching strip is in the open position, if the temperature T is below the switching temperature T s, and is in the closing position and thereby closing a valve bore, if the temperature T is above the switching temperature T s.
An ameliorating agent for use in treating chronic obstructive pulmonary disease, containing as an active ingredient a lecithinized superoxide dismutase represented by the following general formula: SOD'(Q-B) m (in the formula SOD' represents a residue of the superoxide dismutase; Q represents a chemical crosslinking; B represents a residue without a hydrogen atom of a hydroxyl group of lysolecithin having the hydroxyl group at the 2-position of glycerol; m is the average number of bonds of lysolecithin to one molecule of superoxide dismutase and represents an integer of 1 or more).
A power converter comprising: a DC link including a first power supply line and a second power supply line; a converter configured receive a single-phase AC voltage (Vin), and to output a pulsating power Pin to said DC link; an inverter configured to receive a power from said DC link, and to output an AC current (Iu, Iv and Iw); and a power buffer circuit configured to receive a charge power Pl from said DC link, and to output a discharge power Pc to said DC link, wherein said charge power Pl is a power distributed from the pulsating power Pin to the power buffer circuit at a distribution ratio; characterized in that when at least said pulsating power Pin exceeds a predetermined value, said distribution ratio is set as a positive value less than 1/2 and an absolute value of Pc-Pl between said discharge power Pc and said charge power Pl is made smaller than an AC component Pin^ of said pulsating power Pin according to said distribution ratio. a DC link including a first power supply line and a second power supply line; a converter configured receive a single-phase AC voltage (Vin), and to output a pulsating power Pin to said DC link; an inverter configured to receive a power from said DC link, and to output an AC current (Iu, Iv and Iw); and a power buffer circuit configured to receive a charge power Pl from said DC link, and to output a discharge power Pc to said DC link, wherein said charge power Pl is a power distributed from the pulsating power Pin to the power buffer circuit at a distribution ratio; characterized in that when at least said pulsating power Pin exceeds a predetermined value, said distribution ratio is set as a positive value less than 1/2 and an absolute value of Pc-Pl between said discharge power Pc and said charge power Pl is made smaller than an AC component Pin^ of said pulsating power Pin according to said distribution ratio.
A replacement valve for use within the human body comprising a valve component comprising an outer surface covered at least partially with fabric and a stent component for housing the valve component, wherein the stent component and valve component are capable of at least a collapsed configuration for delivery, and an expanded configuration after implantation, the fabric comprising a skirt (902, 1002) with a free edge folded over a bottom portion of the stent component and sutured to the stent component, characterized in that the free edge comprises at least one cut, wherein the at least one cut is oriented in a direction of a longitudinal axis of the stent component.
A vehicle light (1, 2, 3, 4), comprising: a light source including a semiconductor light-emitting element; a wavelength conversion member (12, 22, 32, 42) including a phosphor (12, 22, 32, 42) configured to receive excitation light having been emitted from the semiconductor light-emitting element and then emitting visible light; and a reflector (13, 23, 33, 43) having a reflection surface (132, 231, 331, 431) that reflects the visible light having been emitted from the phosphor (12, 22, 32, 42), characterized in that the reflection surface (132, 231, 331, 431) of the reflector (13, 23, 33, 43) has an optical structure that can diffuse the excitation light incident on the reflection surface from the phosphor (12, 22, 32, 42). a light source including a semiconductor light-emitting element; a wavelength conversion member (12, 22, 32, 42) including a phosphor (12, 22, 32, 42) configured to receive excitation light having been emitted from the semiconductor light-emitting element and then emitting visible light; and a reflector (13, 23, 33, 43) having a reflection surface (132, 231, 331, 431) that reflects the visible light having been emitted from the phosphor (12, 22, 32, 42), characterized in that the reflection surface (132, 231, 331, 431) of the reflector (13, 23, 33, 43) has an optical structure that can diffuse the excitation light incident on the reflection surface from the phosphor (12, 22, 32, 42).
Method for recognizing and visualizing system uncertainty in the representation of augmented image contents (11, 12, 13) in a head-up display (5, 7) in a means of locomotion, in which - an image of the real world is captured with the aid of a camera and transferred to a control apparatus, - augmented image contents (11, 12, 13), which can be represented in the head-up display (5, 7) in such a way that from the point of view of the observer they are integrated into the image of the real world, are ascertained, characterized in that - a characteristic value, which is suitable for assessing the system uncertainty in the representation of the augmented image contents (11, 12, 13), is ascertained, wherein one or more of the following measures are taken for ascertaining the characteristic value: an evaluation of the GPS signal quality, an evaluation of the accuracy of the map material available at the current location, an evaluation of the instantaneous vehicle body movements, a comparison of the location-related information stored in the map material with the information from the camera image, or a direct evaluation of the image on the HUD display; - and - the augmented image contents (11, 12, 13) are adapted depending on the ascertained characteristic value in order to reduce the perceptibility of the representation inaccuracy, wherein the augmented image contents (11, 12, 13) are set into a motion of their own relative to the real image describing the system uncertainty. - an image of the real world is captured with the aid of a camera and transferred to a control apparatus, - augmented image contents (11, 12, 13), which can be represented in the head-up display (5, 7) in such a way that from the point of view of the observer they are integrated into the image of the real world, are ascertained, characterized in that - a characteristic value, which is suitable for assessing the system uncertainty in the representation of the augmented image contents (11, 12, 13), is ascertained, wherein one or more of the following measures are taken for ascertaining the characteristic value: an evaluation of the GPS signal quality, an evaluation of the accuracy of the map material available at the current location, an evaluation of the instantaneous vehicle body movements, a comparison of the location-related information stored in the map material with the information from the camera image, or a direct evaluation of the image on the HUD display; - and - the augmented image contents (11, 12, 13) are adapted depending on the ascertained characteristic value in order to reduce the perceptibility of the representation inaccuracy, wherein the augmented image contents (11, 12, 13) are set into a motion of their own relative to the real image describing the system uncertainty.