A worksite management system comprising: multiple mobile machines (12, 14, 16) operating at a common worksite; a control module located onboard each of the multiple mobile machines (12, 14, 16) and configured to control operations of the respective mobile machine and to collect data associated with at least one of a machine operation at the worksite and a worksite condition; and a controller in remote communication with the control modules and configured to: anticipate a non-failure machine performance irregularity for at least one of the multiple mobile machines based on at least one of a weather condition, a payload, a braking event, wheel slip, machine location, and a worksite condition by analyzing historical data collected by the control module of the at least one or one or more of the other multiple mobile machines (12, 14, 16) located at the common worksite; determine an adjustment to an operation of the at least one mobile machine that positively affects the anticipated non-failure machine performance irregularity by comparing an occurrence history variable associated with the performance irregularity to a threshold value; and cause implementation of the adjustment before the machine performance irregularity is anticipated to occur; wherein the adjustment includes a temporary modification of at least one of an engine speed, a transmission shifting, an acceleration, a differential locking, a braking, a machine maneuvering, and a timing of machine maneuvering relative to worksite locations, when the occurrence history variable is less than the threshold value; wherein the adjustment includes a semi-permanent reconfiguration of at least one of a transmission shift map, a torque limit map, and an engine calibration, when the occurrence history variable is greater than the threshold value, wherein the semi-permanent reconfiguration affects future performances of the machine. multiple mobile machines (12, 14, 16) operating at a common worksite; a control module located onboard each of the multiple mobile machines (12, 14, 16) and configured to control operations of the respective mobile machine and to collect data associated with at least one of a machine operation at the worksite and a worksite condition; and a controller in remote communication with the control modules and configured to: anticipate a non-failure machine performance irregularity for at least one of the multiple mobile machines based on at least one of a weather condition, a payload, a braking event, wheel slip, machine location, and a worksite condition by analyzing historical data collected by the control module of the at least one or one or more of the other multiple mobile machines (12, 14, 16) located at the common worksite; determine an adjustment to an operation of the at least one mobile machine that positively affects the anticipated non-failure machine performance irregularity by comparing an occurrence history variable associated with the performance irregularity to a threshold value; and cause implementation of the adjustment before the machine performance irregularity is anticipated to occur; wherein the adjustment includes a temporary modification of at least one of an engine speed, a transmission shifting, an acceleration, a differential locking, a braking, a machine maneuvering, and a timing of machine maneuvering relative to worksite locations, when the occurrence history variable is less than the threshold value; wherein the adjustment includes a semi-permanent reconfiguration of at least one of a transmission shift map, a torque limit map, and an engine calibration, when the occurrence history variable is greater than the threshold value, wherein the semi-permanent reconfiguration affects future performances of the machine. anticipate a non-failure machine performance irregularity for at least one of the multiple mobile machines based on at least one of a weather condition, a payload, a braking event, wheel slip, machine location, and a worksite condition by analyzing historical data collected by the control module of the at least one or one or more of the other multiple mobile machines (12, 14, 16) located at the common worksite; determine an adjustment to an operation of the at least one mobile machine that positively affects the anticipated non-failure machine performance irregularity by comparing an occurrence history variable associated with the performance irregularity to a threshold value; and cause implementation of the adjustment before the machine performance irregularity is anticipated to occur; determine an adjustment to an operation of the at least one mobile machine that positively affects the anticipated non-failure machine performance irregularity by comparing an occurrence history variable associated with the performance irregularity to a threshold value; and cause implementation of the adjustment before the machine performance irregularity is anticipated to occur; wherein the adjustment includes a temporary modification of at least one of an engine speed, a transmission shifting, an acceleration, a differential locking, a braking, a machine maneuvering, and a timing of machine maneuvering relative to worksite locations, when the occurrence history variable is less than the threshold value; wherein the adjustment includes a semi-permanent reconfiguration of at least one of a transmission shift map, a torque limit map, and an engine calibration, when the occurrence history variable is greater than the threshold value, wherein the semi-permanent reconfiguration affects future performances of the machine.