A compound of Formula I where: X is C or N; R 1 is hydrogen or Ar 1; R 2 is hydrogen or Ar 1; provided that when X is C either R 1 is Ar 1 and R 2 is hydrogen or R 2 is Ar 1 and R 1 is hydrogen, and when X is N R 1 is Ar 1 and R 2 is hydrogen; R 3 is N(R 6)(R 7); R 4 is C 1 to C 6 alkyl or haloalkyl; R 5 is C 1 to C 6 alkyl; R 6 is hydrogen or C 1 to C 6 alkyl; R 7 is hydrogen or C 1 to C 6 alkyl; or N(R 6)(R 7) taken together is azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl, homopiperidinyl, homopiperazinyl, or homomorpholinyl, and is substituted with 0-3 substituents selected from halo, C 1 to C 6 alkyl, haloalkyl, hydroxy, alkoxy, haloalkoxy, carboxy, or carboxamido; or N(R 6)(R 7) taken together is indolinyl, isoindolinyl, tetrahydroisoquinolinyl, or decahydroisoquinolinyl, and is substituted with 0-3 substituents selected from halo, C 1 to C 6 alkyl, haloalkyl, hydroxy, alkoxy, haloalkoxy, carboxy, or carboxamido; or N(R 6)(R 7) taken together is a [4.2.0,], [4.3.0,], [4.4.0,], [4.5.0,], [4.6.0,], [5.2.0,], [5.3.0,], [5.4.0,], [5.5.0,], [5.6.0,], [6.2.0,], [6.3.0,], [6.4.0,], [6.5.0,], [6.6.0,] spirocyclic amine; or N(R 6)(R 7) taken together is and Ar 1 is phenyl, pyridinyl, or biphenyl and is substituted with 0-3 substituents selected from halo, C 1 to C 6 alkyl, haloalkyl, C 3 to C 7 cycloalkyl, halocycloalkyl, alkoxy, haloalkoxy, phenyl, benzyl, phenoxy, and benzyloxy wherein said phenyl, benzyl, phenoxy, and benzyloxy is substituted with 0-3 halo, C 1 to C 6 alkyl, haloalkyl, C 3 to C 7 cycloalkyl, halocycloalkyl, alkoxy, and haloalkoxy substituents; or Ar 1 is tetralinyl, ((methyl)indazolyl)phenyl, or (benzyloxy)phenyl; or a pharmaceutically acceptable salt thereof. X is C or N; R 1 is hydrogen or Ar 1; R 2 is hydrogen or Ar 1; provided that when X is C either R 1 is Ar 1 and R 2 is hydrogen or R 2 is Ar 1 and R 1 is hydrogen, and when X is N R 1 is Ar 1 and R 2 is hydrogen; R 3 is N(R 6)(R 7); R 4 is C 1 to C 6 alkyl or haloalkyl; R 5 is C 1 to C 6 alkyl; R 6 is hydrogen or C 1 to C 6 alkyl; R 7 is hydrogen or C 1 to C 6 alkyl; or N(R 6)(R 7) taken together is azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl, homopiperidinyl, homopiperazinyl, or homomorpholinyl, and is substituted with 0-3 substituents selected from halo, C 1 to C 6 alkyl, haloalkyl, hydroxy, alkoxy, haloalkoxy, carboxy, or carboxamido; or N(R 6)(R 7) taken together is indolinyl, isoindolinyl, tetrahydroisoquinolinyl, or decahydroisoquinolinyl, and is substituted with 0-3 substituents selected from halo, C 1 to C 6 alkyl, haloalkyl, hydroxy, alkoxy, haloalkoxy, carboxy, or carboxamido; or N(R 6)(R 7) taken together is a [4.2.0,], [4.3.0,], [4.4.0,], [4.5.0,], [4.6.0,], [5.2.0,], [5.3.0,], [5.4.0,], [5.5.0,], [5.6.0,], [6.2.0,], [6.3.0,], [6.4.0,], [6.5.0,], [6.6.0,] spirocyclic amine; or N(R 6)(R 7) taken together is and Ar 1 is phenyl, pyridinyl, or biphenyl and is substituted with 0-3 substituents selected from halo, C 1 to C 6 alkyl, haloalkyl, C 3 to C 7 cycloalkyl, halocycloalkyl, alkoxy, haloalkoxy, phenyl, benzyl, phenoxy, and benzyloxy wherein said phenyl, benzyl, phenoxy, and benzyloxy is substituted with 0-3 halo, C 1 to C 6 alkyl, haloalkyl, C 3 to C 7 cycloalkyl, halocycloalkyl, alkoxy, and haloalkoxy substituents; or Ar 1 is tetralinyl, ((methyl)indazolyl)phenyl, or (benzyloxy)phenyl;