A method implemented in a system including an image capture device for using color images to assess a wound of a patient, comprising: during an initial registration stage: (a) capturing one or more first images of one or more baseline regions which are parts of the patient's body; (b) storing, in a database, the one or more first images and/or color data of the one or more first images; during a wound assessment stage: (c) retrieving, from the database, the one or more first images and/or color data of the one or more first images; (d) capturing one or more second images of the one or more baseline regions; (e) capturing a third image containing the wound and its surrounding area; (f) calculating color compensation data by comparing color data of the second images and corresponding color data of the first images, and compensating color values of the third image based on the calculated color compensation data; and (g) assessing the wound using the compensated third image containing the wound and its surrounding area, characterized by: during the initial registration stage: capturing a fourth image containing the wound and its surrounding area; designating one or more regions of the surrounding area of the fourth image as secondary reference regions; and storing, in the database, the fourth image and locations of the designated secondary reference regions of the fourth image, and wherein step (e) includes: overlaying on a viewfinder of the image capture device an indication of a boundary of the wound in the fourth image and an indication of the locations of the secondary reference regions of the fourth image. during an initial registration stage: (a) capturing one or more first images of one or more baseline regions which are parts of the patient's body; (b) storing, in a database, the one or more first images and/or color data of the one or more first images; (a) capturing one or more first images of one or more baseline regions which are parts of the patient's body; (b) storing, in a database, the one or more first images and/or color data of the one or more first images; during a wound assessment stage: (c) retrieving, from the database, the one or more first images and/or color data of the one or more first images; (d) capturing one or more second images of the one or more baseline regions; (e) capturing a third image containing the wound and its surrounding area; (f) calculating color compensation data by comparing color data of the second images and corresponding color data of the first images, and compensating color values of the third image based on the calculated color compensation data; and (g) assessing the wound using the compensated third image containing the wound and its surrounding area, characterized by: (c) retrieving, from the database, the one or more first images and/or color data of the one or more first images; (d) capturing one or more second images of the one or more baseline regions; (e) capturing a third image containing the wound and its surrounding area; (f) calculating color compensation data by comparing color data of the second images and corresponding color data of the first images, and compensating color values of the third image based on the calculated color compensation data; and (g) assessing the wound using the compensated third image containing the wound and its surrounding area, characterized by: during the initial registration stage: capturing a fourth image containing the wound and its surrounding area; designating one or more regions of the surrounding area of the fourth image as secondary reference regions; and storing, in the database, the fourth image and locations of the designated secondary reference regions of the fourth image, and wherein step (e) includes: overlaying on a viewfinder of the image capture device an indication of a boundary of the wound in the fourth image and an indication of the locations of the secondary reference regions of the fourth image. capturing a fourth image containing the wound and its surrounding area; designating one or more regions of the surrounding area of the fourth image as secondary reference regions; and storing, in the database, the fourth image and locations of the designated secondary reference regions of the fourth image, and wherein step (e) includes: overlaying on a viewfinder of the image capture device an indication of a boundary of the wound in the fourth image and an indication of the locations of the secondary reference regions of the fourth image.