mhurhangee/ep-ind-claims huggingface dataset:
A method of analyzing a biological sample, comprising: (a) contacting the biological sample on a first substrate with one or more first nucleic acid probes that hybridize to a first target nucleic acid in the biological sample, wherein the first target nucleic acid is an RNA; (b) imaging the biological sample to detect the one or more first nucleic acid probes at a spatial location of the biological sample, wherein the one or more first nucleic acid probes comprise one or more barcode sequences which correspond to a sequence of the first target nucleic acid; (c) providing conditions to allow a plurality of capture agents to interact with a ligation product which has been released from the biological sample, wherein the ligation product is generated from templated ligation of a pair of probes hybridized to a second target nucleic acid, wherein the plurality of capture agents are joined directly or indirectly to a second substrate, and wherein a capture agent of the plurality of capture agents comprises: (i) a capture domain capable of capturing the ligation product, and (ii) a spatial barcode; and (d) generating a spatially labeled polynucleotide comprising (i) a sequence of the ligation product or complement thereof and (ii) a sequence of the spatial barcode or complement thereof. (a) contacting the biological sample on a first substrate with one or more first nucleic acid probes that hybridize to a first target nucleic acid in the biological sample, wherein the first target nucleic acid is an RNA; (b) imaging the biological sample to detect the one or more first nucleic acid probes at a spatial location of the biological sample, wherein the one or more first nucleic acid probes comprise one or more barcode sequences which correspond to a sequence of the first target nucleic acid; (c) providing conditions to allow a plurality of capture agents to interact with a ligation product which has been released from the biological sample, wherein the ligation product is generated from templated ligation of a pair of probes hybridized to a second target nucleic acid, wherein the plurality of capture agents are joined directly or indirectly to a second substrate, and wherein a capture agent of the plurality of capture agents comprises: (i) a capture domain capable of capturing the ligation product, and (ii) a spatial barcode; and (i) a capture domain capable of capturing the ligation product, and (ii) a spatial barcode; and (d) generating a spatially labeled polynucleotide comprising (i) a sequence of the ligation product or complement thereof and (ii) a sequence of the spatial barcode or complement thereof.
A tape measure, comprising: a housing having a left side and a right side surrounding a front of the housing; a tape selectively extendable from, and retractable to, the front of the housing; and a slide lock at the front of the housing configured to selectively clamp the tape to the housing to prevent extension and retraction of the tape from the front of the housing when the slide lock is in a locked position; wherein the slide lock comprises an actuator on an exterior of the housing and a lock engagement tab on an interior of the housing, the actuator and the lock engagement tab being coupled together by a portion of the slide lock extending through a channel in which the slide lock is slidable; wherein the lock engagement tab engages with a protrusion in the housing when moving the slide lock from the locked position to an unlocked position, such that movement of the slide lock into the unlocked position requires depression of the actuator towards the interior of the housing; characterized in that the depression of the actuator towards the interior of the housing is required to disengage the lock engagement tab from the protrusion. a housing having a left side and a right side surrounding a front of the housing; a tape selectively extendable from, and retractable to, the front of the housing; and a slide lock at the front of the housing configured to selectively clamp the tape to the housing to prevent extension and retraction of the tape from the front of the housing when the slide lock is in a locked position; wherein the slide lock comprises an actuator on an exterior of the housing and a lock engagement tab on an interior of the housing, the actuator and the lock engagement tab being coupled together by a portion of the slide lock extending through a channel in which the slide lock is slidable; wherein the lock engagement tab engages with a protrusion in the housing when moving the slide lock from the locked position to an unlocked position, such that movement of the slide lock into the unlocked position requires depression of the actuator towards the interior of the housing; characterized in that the depression of the actuator towards the interior of the housing is required to disengage the lock engagement tab from the protrusion.
Lighting and/or signalling module especially for an automotive vehicle, comprising a member for supporting optical means for deviating light rays emitted by a first stationary light source, the module furthermore comprising a frame comprising two screens (28, 30), at least one of which plays the role of an optical guide, and a base connecting them transversely at one of their ends, said frame being mounted so as to be rotatable about an axis under the effect of an actuator, so that said two screens are able to adopt alternatively an active position upstream of the supporting member, especially on the path of the light rays deviated by said optical deviating means, and in which the screen in the active position is located plumb with a second stationary light source, the module comprising at least one additional optical device that extends between the screens.
A phacoemulsification surgical console, comprising: a cassette receiver suitable for receiving a surgical cassette; a controller suitable for controlling provided aspects of a phacoemulsification provided at least partially by the phacoemulsification surgical console; and a pre-alignment feature along a lower portion under and proximate to the cassette receiver, extending outwardly from the lower portion, and suitable for aligning the surgical cassette to the cassette receiver characterized in that the pre-alignment feature comprises a shelf wherein the outward extension varies along the shelf. a cassette receiver suitable for receiving a surgical cassette; a controller suitable for controlling provided aspects of a phacoemulsification provided at least partially by the phacoemulsification surgical console; and a pre-alignment feature along a lower portion under and proximate to the cassette receiver, extending outwardly from the lower portion, and suitable for aligning the surgical cassette to the cassette receiver characterized in that the pre-alignment feature comprises a shelf wherein the outward extension varies along the shelf.
A filling system comprising: a conveyance chamber that conveys vessels; a plurality of filling chambers (13, 15, 17) provided with filling means for filling contents into the vessels; and a pressure control means that controls the pressure conditions of each chamber; wherein an intermediate chamber (13M, 15M, 17M) is provided between the conveyance chamber and the filling chamber (13, 15, 17); wherein an opening/closing door is provided that can separate the conveyance chamber and the intermediate chamber (13M, 15M, 17M); and when at least one filling chamber (13, 15, 17) and at least one intermediate chamber (13M, 15M, 17M) are separated from the conveyance chamber by closing the opening/closing door while cleaning a filling machine (12, 14, 16), the pressure control means controls the pressure of the intermediate chamber (13M, 15M, 17M) to become lower than the pressure of the conveyance chamber and the filling chamber (13, 15, 17). a conveyance chamber that conveys vessels; a plurality of filling chambers (13, 15, 17) provided with filling means for filling contents into the vessels; and a pressure control means that controls the pressure conditions of each chamber; wherein an intermediate chamber (13M, 15M, 17M) is provided between the conveyance chamber and the filling chamber (13, 15, 17); wherein an opening/closing door is provided that can separate the conveyance chamber and the intermediate chamber (13M, 15M, 17M); and when at least one filling chamber (13, 15, 17) and at least one intermediate chamber (13M, 15M, 17M) are separated from the conveyance chamber by closing the opening/closing door while cleaning a filling machine (12, 14, 16), the pressure control means controls the pressure of the intermediate chamber (13M, 15M, 17M) to become lower than the pressure of the conveyance chamber and the filling chamber (13, 15, 17).
Use of a bar as an outer pressure bar for supporting two façade elements (2a, 2b) on a supporting element, in particular a post-and-beam façade, wherein the bar is designed as a plastic profile with a core made of foam material and an outer portion surrounding the core, and the outer portion has a greater hardness than the core.
A computer-implemented method, comprising: identifying, by one or more processors, a skill disparity between at least two players of a game based on player skill data provided by a player skill engine; selecting, based on the skill disparity between the at least two players, by the one or more of the processors, an ambient lighting scheme from a database to reduce an impact the skill disparity has on an outcome of the game, wherein the ambient lighting scheme comprises a property of emitted light selected to impair or enhance an ability of a first player of the at least two players to play the game; selecting, by one or more of the processors, one or more ambient light sources from a plurality of ambient light sources based on positions of the at least two players relative to the plurality of ambient light sources; and operating, by the one or more of the processors, the one or more ambient light sources (104, 304) to emit light in accordance with the ambient lighting scheme. identifying, by one or more processors, a skill disparity between at least two players of a game based on player skill data provided by a player skill engine; selecting, based on the skill disparity between the at least two players, by the one or more of the processors, an ambient lighting scheme from a database to reduce an impact the skill disparity has on an outcome of the game, wherein the ambient lighting scheme comprises a property of emitted light selected to impair or enhance an ability of a first player of the at least two players to play the game; selecting, by one or more of the processors, one or more ambient light sources from a plurality of ambient light sources based on positions of the at least two players relative to the plurality of ambient light sources; and operating, by the one or more of the processors, the one or more ambient light sources (104, 304) to emit light in accordance with the ambient lighting scheme.
Method for displaying event-related content on a mobile terminal, wherein the content comprises a first component and a second component linked to the first component and the second component can be displayed on the mobile terminal based on an operating action that can be performed during a display of the first component, wherein the first component of the content is received in connection with the second component of the content in the mobile terminal, and the first component of the content is only displayed on the mobile terminal when the second component of the content has been partially received in the mobile terminal, wherein the display of the first component of the content is delayed until a predetermined portion of the second component has been received in the mobile terminal and wherein the first component is displayed before the second component has been completely transmitted to the mobile terminal, characterised in that the first component and/or the second component of the content are displayed together with a graphic element and that the graphic element is stored on the mobile terminal under an identifier in a memory, wherein only the identifier of the graphic element is transmitted from a server to the mobile terminal.
A method for screening for lactic acid bacteria having immunoregulatory functions comprising determining the number of test lactic acid bacteria bound to a uromodulin (Umod) protein, wherein test lactic acid bacteria having immunoregulatory functions are selected when the number of the test lactic acid bacteria bound to the uromodulin (Umod) protein is larger than or equivalent to the number of the Lactobacillus acidophilus L-92 strain bound to the uromodulin (Umod) protein.
A drive unit for a trailer comprising drive means, power means and mounting means, the mounting means being arranged, in use, to be secured to the trailer, the drive means being arranged to rotate a wheel of a trailer around an axle of the trailer, the drive means comprising actuating means to actuate engagement means between a disengaged configuration and an engaged configuration in which the engagement means transmits movement of the drive means to a wheel of the trailer, characterised in that: the power means is detachably connected to the drive means by power leads (102, 106) said detachable connection comprising connector plugs (104, 105, 111, 114) and wherein the power means is provided in a portable case, the drive unit further comprises control means to control the movement of the trailer by the drive unit and wherein the control means comprise a control unit located in the portable case and an operating device which comprises a remote control unit.
Steel material for the manufacture of pumps or the like, characterised in that the steel material features the following analysis in wt%: C ≤ 0.030; Si ≤ 0.40; Mn ≤ 0.60; P ≤ 0.025; S ≤ 0.005; Cr = 14.20 − 14.60; Mo = 0.30 − 0.45; Ni = 4.80 − 5.20; V < 0.10; W < 0.10; Cu = 3.00 − 3.70; Co < 0.15; Ti < 0.010; Al < 0.030; Nb < 0.02; Ta < 0.02; N < 0.02; remainder iron and unavoidable impurities, wherein the structure of the steel material consists of martensite with maximum 1% delta ferrite, wherein the structure is free of primary hard phases, in particular with a niobium, tantalum, titanium or vanadium base, and the temper austenite content is maximum 8%, wherein the steel material at a precipitation hardening temperature of 520°C attains a yield strength of approx. 1000 MPa with a toughness of more than 70 J at -40°C and at a precipitation hardening temperature of 485°C a yield strength of approx. 1100 MPa with a toughness of more than 60 J at -40°C, wherein the values of the mechanical properties are related to measurements in the transverse direction.
Valve for metering fluid, having a metering opening which is connected to a fluid inlet, having a valve needle which controls the metering opening, having an electromagnet for the valve needle actuation, which electromagnet has an armature. which engages on the valve needle, and which electromagnet has a hollow cylindrical magnet core which is coaxial with respect to said armature and which, together with the armature, delimits a working air gap, having a valve closing spring which acts on the valve needle in order to close the metering opening and which is arranged within the magnet core on the valve needle and which is supported axially at the valve needle side and at the magnet core side, and having a guide element which is received in the magnet core and which serves for the sliding guidance of the valve needle, wherein the guide element is arranged on that end of the valve closing spring which is averted from the armature, wherein the guide element is fixed in the magnet core and, at one side, centrally receives an end section of the valve needle in axially displaceable fashion and, at the other side, performs the support of the valve closing spring at the magnet core side, and wherein the guide element is in the form of a hollow cylindrical sleeve with a sleeve wall which is delimited by an inner and outer surface, which sleeve has a guide region for the valve needle and a pressing region for pressing into the magnet core, characterized in that the guide region and the pressing region are arranged axially one behind the other and are separated from one another by a constriction which is formed by an axial section of the sleeve of reduced external diameter.
Fuel distributor, in particular for fuel injection systems of mixture-compression, auto-ignition internal combustion engines, having a distributor piece, having multiple valve cups (3 - 6) arranged on the distributor piece and having a clamping part, wherein the clamping part is supported on the distributor piece and supports the valve cups (3 - 6), and wherein the clamping part is preloaded and forces the valve cups (3 - 6) against the distributor piece with the preload.
A process for producing a renewable fuel, said process comprising: (a) thermochemically converting lignocellulosic biomass by fast pyrolysis in a riser reactor and in the presence of a catalyst to thereby provide a bio-oil having an oxygen content in the range of 15 to 50 weight percent; (b) separating said bio-oil into at least a light fraction, an intermediate fraction, and a heavy fraction, wherein the mid-boiling point of said heavy fraction is at least 100°C greater than the mid-boiling point of said light fraction, wherein said intermediate fraction has a mid-boiling point between the mid-boiling points of said light fraction and said heavy fraction; and (c) hydrotreating at least a portion of said light fraction to thereby provide a hydrotreated light fraction. (a) thermochemically converting lignocellulosic biomass by fast pyrolysis in a riser reactor and in the presence of a catalyst to thereby provide a bio-oil having an oxygen content in the range of 15 to 50 weight percent; (b) separating said bio-oil into at least a light fraction, an intermediate fraction, and a heavy fraction, wherein the mid-boiling point of said heavy fraction is at least 100°C greater than the mid-boiling point of said light fraction, wherein said intermediate fraction has a mid-boiling point between the mid-boiling points of said light fraction and said heavy fraction; and (c) hydrotreating at least a portion of said light fraction to thereby provide a hydrotreated light fraction.
A method of isolating a 4-chloro-2-fluoro-3-substituted-phenylboronate, comprising: adding carbon dioxide gas or carbon dioxide solid (dry ice) to a solution comprising a 4-chloro-2-fluoro-3-substituted-phenylboronate, an inert organic solvent, and at least one lithium salt to react the at least one lithium salt with the carbon dioxide gas and form a mixture comprising the 4-chloro-2-fluoro-3-substituted-phenylboronate, the inert organic solvent, and a precipitated solid; and removing the precipitated solid from the mixture. adding carbon dioxide gas or carbon dioxide solid (dry ice) to a solution comprising a 4-chloro-2-fluoro-3-substituted-phenylboronate, an inert organic solvent, and at least one lithium salt to react the at least one lithium salt with the carbon dioxide gas and form a mixture comprising the 4-chloro-2-fluoro-3-substituted-phenylboronate, the inert organic solvent, and a precipitated solid; and removing the precipitated solid from the mixture.
Apparatus for endoscopic submucosal dissection in the upper or lower gastrointestinal tract, comprising a tube, which has at least one lumen running in the longitudinal direction thereof, wherein an actuating wire, which can be energized by high-frequency current, runs through the at least one lumen, a high-frequency tool acting as a knife engages the distal end of said wire and an actuating element supported on the tube engages the proximal end of said wire, characterized in that the high-frequency tool acting as a knife is formed as a stranded wire, which is adjustable into at least three working positions, wherein, in a first maximally extended position of the distal end of the actuating wire, the stranded wire assumes a working position in which it has a substantially crescent-shaped outer contour, in that a portion of the stranded wire that is connected to the actuating wire is formed with a smaller radius of a concavely running curvature in comparison with a portion thereof that is provided with a free end, in that, at least in the region of its crescent-shaped convexly running outer contour, the stranded wire is provided with a cutting edge, facing both inward and outward and is adjustable into two further working positions, whereby the stranded wire in a second working position follows an approximately hairpin-like path in a substantially half-extended position of the distal end of the actuating wire and in a third working position lies completely within the lumen in a retracted position of the actuating wire, and in that the tube is formed at its distal end for piercing into the mucosa, wherein the lumen receiving the actuating wire or a further lumen running in the tube is formed as an injection device.
An aqueous soy flour slurry comprising: i) from 10 to 60 weight percent defatted soy flour based on the total weight of the slurry, ii) from 0.2% to 4% by weight, based on the total weight of the slurry, of a water soluble polymer dispersing agent made by the polymerization of ethylenically unsaturated monomers and having a weight average molecular weight, measured by gel permeation chromatography using polyacrylic acid standards, in the range of from 1,000 to 20,000, and iii) water, wherein the water soluble polymer dispersing agent is a homopolymer or copolymer comprising polymerized units derived from one or more monomers selected from the group consisting of (meth)acrylic acid, (meth)acrylates, maleic acid; anhydrides thereof; and salts thereof, or the water soluble polymer dispersing agent comprises a water soluble phosphorous containing polymer; wherein the viscosity of the slurry is in the range from 200 to 2,000 mPa.s (cps) as measured by a DV-III Ultra LV Brookfield viscometer at 6 rpm using spindle # 31 at 25°C; and further wherein the term "defatted soy flour" refers to a soy flour where the oil component of the soy flour has been removed, or "defatted", to levels below 1.5%, but excludes soy protein concentrate and soy protein isolate. i) from 10 to 60 weight percent defatted soy flour based on the total weight of the slurry, ii) from 0.2% to 4% by weight, based on the total weight of the slurry, of a water soluble polymer dispersing agent made by the polymerization of ethylenically unsaturated monomers and having a weight average molecular weight, measured by gel permeation chromatography using polyacrylic acid standards, in the range of from 1,000 to 20,000, and iii) water,
A heat accumulator, comprising a storage tank having heating water, feed and discharge pipes (4, 5) for the heating water which are flow-connected to the storage tank, and at least one heat exchanger which is provided in the storage tank for its loading and which comprises a flow channel flow-connected to the heating water of the storage tank and a heat-exchanger line which is provided at least partly in the flow channel for guiding a heat carrier that is in indirect heat exchange with the heating water of the flow channel, wherein the flow channel of the heat exchanger comprises a non-return valve, characterized in that the feed pipe enters the flow channel in its direction of flow after its non-return valve.