mhurhangee/ep-ind-claims huggingface dataset:
A regulatable chimeric antigen receptor (RCAR), wherein the RCAR comprises: a first polypeptide that is an intracellular signaling member comprising an intracellular signaling domain and a first switch domain, and a second polypeptide that is an antigen binding member that comprises an antigen binding domain and a second switch domain, wherein the first and second switch domains associate in the presence of a dimerization molecule, further wherein the RCAR comprises a transmembrane domain, and wherein the first and second switch domains comprise a FKBP-FRB based switch comprising: (a) a switch domain that comprises a FRB binding fragment or sequence having at least 80, 85, 90, 95, 98 or 99% identity with the FKBP sequence of SEQ ID NO: 1 or 141; and (b) a switch domain comprising an FKBP binding fragment or sequence having at least 80, 85, 90, 95, 98 or 99% identity with the FRB sequence of SEQ ID NO: 2, and comprising an E2032 mutation, or an E2032 mutation and a T2098 mutation, wherein the first amino acid of SEQ ID NO: 2 is defined as position 2021. a first polypeptide that is an intracellular signaling member comprising an intracellular signaling domain and a first switch domain, and a second polypeptide that is an antigen binding member that comprises an antigen binding domain and a second switch domain, wherein the first and second switch domains associate in the presence of a dimerization molecule, further wherein the RCAR comprises a transmembrane domain, and wherein the first and second switch domains comprise a FKBP-FRB based switch comprising: (a) a switch domain that comprises a FRB binding fragment or sequence having at least 80, 85, 90, 95, 98 or 99% identity with the FKBP sequence of SEQ ID NO: 1 or 141; and (b) a switch domain comprising an FKBP binding fragment or sequence having at least 80, 85, 90, 95, 98 or 99% identity with the FRB sequence of SEQ ID NO: 2, and comprising an E2032 mutation, or an E2032 mutation and a T2098 mutation, wherein the first amino acid of SEQ ID NO: 2 is defined as position 2021. (a) a switch domain that comprises a FRB binding fragment or sequence having at least 80, 85, 90, 95, 98 or 99% identity with the FKBP sequence of SEQ ID NO: 1 or 141; and (b) a switch domain comprising an FKBP binding fragment or sequence having at least 80, 85, 90, 95, 98 or 99% identity with the FRB sequence of SEQ ID NO: 2, and comprising an E2032 mutation, or an E2032 mutation and a T2098 mutation, wherein the first amino acid of SEQ ID NO: 2 is defined as position 2021.
An intake for feeding air to an engine of an aircraft, comprising: an opening for sucking in air, which opening points in the direction of movement of the aircraft; and an air duct between the opening and the engine, which air duct is curved in such a way that an impact region is arranged in the air duct after the opening in relation to the direction of movement of the aircraft, such that an object flying into the opening contacts the impact region; wherein the impact region has a predetermined breaking region, which is arranged in a shell-shaped part of the intake, characterized in that the predetermined breaking region protrudes from the aircraft and is designed to separate from the aircraft upon impact of a bird as the object. an opening for sucking in air, which opening points in the direction of movement of the aircraft; and an air duct between the opening and the engine, which air duct is curved in such a way that an impact region is arranged in the air duct after the opening in relation to the direction of movement of the aircraft, such that an object flying into the opening contacts the impact region; wherein the impact region has a predetermined breaking region, which is arranged in a shell-shaped part of the intake, characterized in that the predetermined breaking region protrudes from the aircraft and is designed to separate from the aircraft upon impact of a bird as the object.
A computer-implemented method for decoding at least M 0 symbols X 1 0,..., X M 0 0 received from a transmitter through a wireless communication medium, said received symbols representing symbols encoded by an encoder E of the transmitter, said method comprising: inputting in a decoder the M 0 symbols X 1 0,..., X M 0 0, said decoder comprising an artificial neural network system with N layers, wherein the decoder is defined as a function F which is defined by N sets of functions F 1 i,..., F M i i, with i from 1 to N, wherein each Function F m i corresponds to a neuron of the i-th layer of said artificial neural network system, wherein F m i X 1 i − 1,..., X M i − 1 i − 1 = f m i ∑ k = 1 M i − 1 w k, m i − 1 × X k i − 1 +β m i, with F X 1 0,..., X M 0 0 = F 1 N X 1 N − 1,..., X M N − 1 N − 1,..., F M N N X 1 N − 1,..., X M N − 1 N − 1, where, X m i − 1 are respectively the outputs of the functions F m i − 1, X m i − 1 = F m i − 1 X 1 i − 2,..., X M i − 1 i − 2 of the (i-1)-th set, wherein each f m i is either an artificial neural network activation function or an identity function, and w 1, m i − 1,..., w M i − 1, m i − 1, β m i for m from 1 to M i and for i from 1 to N are real number parameters of said artificial neural network, wherein at least one of the functions f m i with m from 1 to M i and i from 1 to N-1 is a multiple level activation function; wherein a multiple level activation function is an activation function that enables to consider strictly more than two levels of output. inputting in a decoder the M 0 symbols X 1 0,..., X M 0 0, said decoder comprising an artificial neural network system with N layers, wherein the decoder is defined as a function F which is defined by N sets of functions F 1 i,..., F M i i, with i from 1 to N, wherein each Function F m i corresponds to a neuron of the i-th layer of said artificial neural network system, wherein F m i X 1 i − 1,..., X M i − 1 i − 1 = f m i ∑ k = 1 M i − 1 w k, m i − 1 × X k i − 1 +β m i, with F X 1 0,..., X M 0 0 = F 1 N X 1 N − 1,..., X M N − 1 N − 1,..., F M N N X 1 N − 1,..., X M N − 1 N − 1, where, X m i − 1 are respectively the outputs of the functions F m i − 1, X m i − 1 = F m i − 1 X 1 i − 2,..., X M i − 1 i − 2 of the (i-1)-th set, wherein each f m i is either an artificial neural network activation function or an identity function, and w 1, m i − 1,..., w M i − 1, m i − 1, β m i for m from 1 to M i and for i from 1 to N are real number parameters of said artificial neural network, wherein at least one of the functions f m i with m from 1 to M i and i from 1 to N-1 is a multiple level activation function; wherein a multiple level activation function is an activation function that enables to consider strictly more than two levels of output.
A serving node in a telecommunication network, the serving node comprising: an interface configured to exchange data with a user equipment and with a gateway node of the network; and a processor connected to the interface and configured to implement, a classifier function for intercepting a request from the user equipment, wherein the request is related to a desired content, and for analyzing whether the request complies with pre-established categorization rules, a request analyzer function for analyzing the request when the request complies with the pre-established categorization rules and for selecting one mode of plural available modes, wherein each mode is related to performance indicators associated with the desired content, and an application function for requesting a quality of service, QoS, bearer to be established between the serving node and the user equipment when the selected mode includes a QoS requirement, wherein the interface is configured to send the QoS bearer request to the gateway node, and wherein the serving node is configured to provide the desired content to the user equipment. an interface configured to exchange data with a user equipment and with a gateway node of the network; and a processor connected to the interface and configured to implement, a classifier function for intercepting a request from the user equipment, wherein the request is related to a desired content, and for analyzing whether the request complies with pre-established categorization rules, a request analyzer function for analyzing the request when the request complies with the pre-established categorization rules and for selecting one mode of plural available modes, wherein each mode is related to performance indicators associated with the desired content, and an application function for requesting a quality of service, QoS, bearer to be established between the serving node and the user equipment when the selected mode includes a QoS requirement, a classifier function for intercepting a request from the user equipment, wherein the request is related to a desired content, and for analyzing whether the request complies with pre-established categorization rules, a request analyzer function for analyzing the request when the request complies with the pre-established categorization rules and for selecting one mode of plural available modes, wherein each mode is related to performance indicators associated with the desired content, and an application function for requesting a quality of service, QoS, bearer to be established between the serving node and the user equipment when the selected mode includes a QoS requirement, wherein the interface is configured to send the QoS bearer request to the gateway node, and wherein the serving node is configured to provide the desired content to the user equipment.
A machine-implemented method for intercepting computing device system calls, the computing device including a kernel including a system call table, the method comprising: executing a hypervisor on the computing device, the hypervisor configured to control at least one computing device processor register, the at least one computing device processor register configured to be used by the kernel; creating at least one modified kernel structure, the modified kernel structure including a modified system call table as a copy of the system call table; determining a memory address of an original system call handler, the original system call handler configured to receive and execute kernel operation commands; determining a size of a loaded image of the original system call handler; creating a copy of the original system call handler as a second system call handler; and intercepting, by the second system call handler as directed by the hypervisor using the modified system call table, a computing device system call. executing a hypervisor on the computing device, the hypervisor configured to control at least one computing device processor register, the at least one computing device processor register configured to be used by the kernel; creating at least one modified kernel structure, the modified kernel structure including a modified system call table as a copy of the system call table; determining a memory address of an original system call handler, the original system call handler configured to receive and execute kernel operation commands; determining a size of a loaded image of the original system call handler; creating a copy of the original system call handler as a second system call handler; and intercepting, by the second system call handler as directed by the hypervisor using the modified system call table, a computing device system call.
A method of applying a bone attachment coating to a prosthetic component, the bone attachment coating being formed from a plurality of particles applied to a surface of the prosthetic component, characterised in that the method comprises: exciting the plurality of particles with an ultrasonic exciter so as to increase the vibrational energy of the particles without significantly heating the prosthetic component; wherein the vibrational energy of the particles causes localised heating of the prosthetic component such that the particles may be embedded into a bone facing region of the prosthetic component. exciting the plurality of particles with an ultrasonic exciter so as to increase the vibrational energy of the particles without significantly heating the prosthetic component; wherein the vibrational energy of the particles causes localised heating of the prosthetic component such that the particles may be embedded into a bone facing region of the prosthetic component.
An apparatus comprising a processor, a memory, and communication circuitry, the apparatus being connected to a network via its communication circuitry, the apparatus being configured to: either transmit a first control indication pertaining to a first set of time and frequency resources for a first data transmission, wherein the first set of time and frequency resources are allocated as a joint control resource set by the first control indication, the first control indication being transmitted in a physical downlink control channel, PDCCH; or transmit a plurality of second control indications each pertaining to a second set of time and frequency resources for a second data transmission, wherein the second set of time and frequency resources are allocated as a plurality of separate control resource sets by the plurality of second control indications, each of the plurality of second control indications being transmitted in a separate PDCCH and allocating a respective one of the plurality of separate control resource sets; wherein the first control indication and each of the plurality of second control indications comprise (i) a code block group, CBG, transmission indication or a CBG flush indication, (ii) a slot format indication, SFI, and (iii) a pre-emption indication for the first set of time and frequency resources or the second set of time and frequency resources; and transmit, to a User Equipment, UE, the first data transmission in accordance with the first control indication or the second data transmission in accordance with the plurality of second control indications. either transmit a first control indication pertaining to a first set of time and frequency resources for a first data transmission, wherein the first set of time and frequency resources are allocated as a joint control resource set by the first control indication, the first control indication being transmitted in a physical downlink control channel, PDCCH; or transmit a plurality of second control indications each pertaining to a second set of time and frequency resources for a second data transmission, wherein the second set of time and frequency resources are allocated as a plurality of separate control resource sets by the plurality of second control indications, each of the plurality of second control indications being transmitted in a separate PDCCH and allocating a respective one of the plurality of separate control resource sets; wherein the first control indication and each of the plurality of second control indications comprise (i) a code block group, CBG, transmission indication or a CBG flush indication, (ii) a slot format indication, SFI, and (iii) a pre-emption indication for the first set of time and frequency resources or the second set of time and frequency resources; and transmit, to a User Equipment, UE, the first data transmission in accordance with the first control indication or the second data transmission in accordance with the plurality of second control indications.
Turboshaft engine for a helicopter, comprising a housing in which is arranged a gas generator and a turbine mounted on a power shaft extending in a longitudinal direction (X'X), the turboshaft engine comprising means for removably embedding said power shaft in a reduction gearbox in which is arranged at least one gearwheel of a first reduction stage, said means for removable embedding comprising a pinion having a central bore adapted to said power shaft in such a way that said pinion can be fitted on said power shaft, said pinion further having a periphery adapted to said gearwheel of the first stage in such a way that it can form a driving input pinion of the gearbox meshed with said gearwheel, once said power shaft is embedded in said reduction gearbox, said means for removable embedding further comprising a rear pinion bearing and a front pinion bearing each intended to support the assembly formed by said pinion fitted on said power shaft once said power shaft is embedded in said reduction gearbox in the vicinity of a gearbox input and in the vicinity of a gearbox end which is longitudinally opposite said gearbox input respectively, each front bearing and rear bearing further comprising rolling elements (25, 22), an inner ring (26, 23) intended to be centred in abutment against the pinion and an outer ring (27, 24) intended to be centred in abutment against the reduction gearbox, characterised in that said rear bearing of said pinion is rigidly connected to said housing, said rolling elements and the inner ring of said front bearing are mounted on the power shaft, and said outer ring of said front bearing is designed so as to be able to be accommodated in said reduction gearbox and rigidly connected to said reduction gearbox before said power shaft is embedded in said reduction gearbox.
A catheter assembly comprising: a catheter hub comprising a housing comprising an exterior surface and an interior surface defining an interior cavity; a catheter tube attached to the catheter hub and extending distally of the catheter hub; a needle hub (18, 90) comprising a housing comprising an exterior surface and an interior surface defining an interior cavity; a needle (16, 92, 130) having a needle tip attached to the needle hub (18, 90) and projecting distally of the needle hub (18, 90) and into the catheter tube; a valve for limiting blood backflow positioned in the interior cavity of the catheter hub; a valve opener (48, 132, 180, 193) for opening the valve positioned proximally of the valve; and a device for covering the needle (16, 92, 130) positioned adjacent the valve opener (48, 132, 180, 193); characterized in that the device for covering the needle (16, 92, 130) comprises: a tip protector housing having an interior surface; and an arm extending from the tip protector housing to engage the interior surface of the catheter hub and retain the tip protector housing in a ready to use position. a catheter hub comprising a housing comprising an exterior surface and an interior surface defining an interior cavity; a catheter tube attached to the catheter hub and extending distally of the catheter hub; a needle hub (18, 90) comprising a housing comprising an exterior surface and an interior surface defining an interior cavity; a needle (16, 92, 130) having a needle tip attached to the needle hub (18, 90) and projecting distally of the needle hub (18, 90) and into the catheter tube; a valve for limiting blood backflow positioned in the interior cavity of the catheter hub; a valve opener (48, 132, 180, 193) for opening the valve positioned proximally of the valve; and a device for covering the needle (16, 92, 130) positioned adjacent the valve opener (48, 132, 180, 193); characterized in that the device for covering the needle (16, 92, 130) comprises: a tip protector housing having an interior surface; and an arm extending from the tip protector housing to engage the interior surface of the catheter hub and retain the tip protector housing in a ready to use position. a tip protector housing having an interior surface; and an arm extending from the tip protector housing to engage the interior surface of the catheter hub and retain the tip protector housing in a ready to use position.
Energy management system for an agricultural vehicle arrangement, having an electrical energy supply unit for supplying electrical energy to a multiplicity of electrical loads (18, 20, 22, 24, 26, 28), a consumption monitoring unit for determining a total electrical energy requirement that is dependent on a current operating state of the electrical loads (18, 20, 22, 24, 26, 28), wherein the consumption monitoring unit estimates the electrical energy supply available from the electrical energy supply unit and compares it with the determined total electrical energy requirement in order to reduce the supply of electrical energy to the electrical loads (20, 22, 24, 26, 28) on the basis of assigned supply priorities if the available electrical energy supply is exceeded by the determined total energy requirement, characterized in that the consumption monitoring unit dynamically adapts the supply priorities on the basis of a changing cooling requirement of a vehicle assembly cooled by means of at least one of the electrical loads to the effect that, in order to simultaneously comply with the electrical energy supply that is available overall, the total electrical energy requirement is reduced by downgrading the supply priorities of one or more of the other electrical loads (18, 20, 22, 24, 26).
A nonwoven fabric having projections and recesses, comprising extensible fiber and elastic fiber, wherein the first surface of the nonwoven fabric has a plurality of projections and a plurality of recesses, and the proportion of extensible fiber in the projections is higher than the proportion of extensible fiber in the recesses.
An automated fiber placement roller comprising: an elastically deformable rim member arranged about a central axis and having an inner side and an outer side, wherein the central axis is closer to the inner side than to the outer side; a hub member arranged substantially concentric with the rim member about the central axis, wherein the hub member defines an opening to receive a shaft of an automated fiber placement machine; a plurality of curved interconnect members extending between the hub member and the rim member, wherein each of the plurality of curved interconnect members is elastically deformable to accommodate deformation of the rim member; and one or more roller skin layers coupled to the outer side of the rim member; wherein a plurality of grooves are defined in the rim member to reduce a force required to elastically deform the rim member. an elastically deformable rim member arranged about a central axis and having an inner side and an outer side, wherein the central axis is closer to the inner side than to the outer side; a hub member arranged substantially concentric with the rim member about the central axis, wherein the hub member defines an opening to receive a shaft of an automated fiber placement machine; a plurality of curved interconnect members extending between the hub member and the rim member, wherein each of the plurality of curved interconnect members is elastically deformable to accommodate deformation of the rim member; and one or more roller skin layers coupled to the outer side of the rim member; wherein a plurality of grooves are defined in the rim member to reduce a force required to elastically deform the rim member.
A crystalline recombinant interferon comprising the amino acid sequence of SEQ ID NO: 1, wherein the unit cell parameters of the crystal are a=b=77.92 Å, c=125.935 Å, α=β=90°, γ=120°, with a variability of at most 5% in all cell parameters.