mhurhangee/ep-ind-claims huggingface dataset:
An entwined tubular arrangement (40; 60; 80) for a heat exchanger, the arrangement comprising: at least one first thermally conductive tube (44; 64; 84) for conveying a first fluid; at least one second thermally conductive tube (46; 66; 86) for conveying a second fluid; wherein the first and second tubes (44, 46; 64, 66; 84; 86) are wound around one another and in contact with one another in an entwined tubular arrangement; and characterised in that the entwined tubular arrangement (40; 60; 80) is supported by a support structure (50; 70; 90) made of the same thermally conductive material as the first and second tubes. at least one first thermally conductive tube (44; 64; 84) for conveying a first fluid; at least one second thermally conductive tube (46; 66; 86) for conveying a second fluid; wherein the first and second tubes (44, 46; 64, 66; 84; 86) are wound around one another and in contact with one another in an entwined tubular arrangement; and characterised in that the entwined tubular arrangement (40; 60; 80) is supported by a support structure (50; 70; 90) made of the same thermally conductive material as the first and second tubes.
A container [1, 2] for storing and dispensing a liquid, said container including: an access port having a frangible seal for allowing contained liquid to be dispensed; a vent permeable to vapour but impermeable to liquid such that vapour may be vented from the interior of said container; characterized by a sealingly engagable closure centrally disposed in a top portion of said container, wherein said closure includes said access port and said vent, a neck portion having a circumferentially disposed thread protrusion for threaded engagement with a lid, said thread protrusion being periodically interrupted to allow gas transfer between said vent and the atmosphere when said lid is engaged with said neck portion; and wherein said closure includes a plurality of spacer protrusions for spacing said lid away from said vent thereby allowing gas transfer between said vent and the atmosphere when said lid is engaged with said neck portion. an access port having a frangible seal for allowing contained liquid to be dispensed; a vent permeable to vapour but impermeable to liquid such that vapour may be vented from the interior of said container; a sealingly engagable closure centrally disposed in a top portion of said container, wherein said closure includes said access port and said vent, a neck portion having a circumferentially disposed thread protrusion for threaded engagement with a lid, said thread protrusion being periodically interrupted to allow gas transfer between said vent and the atmosphere when said lid is engaged with said neck portion; and wherein said closure includes a plurality of spacer protrusions for spacing said lid away from said vent thereby allowing gas transfer between said vent and the atmosphere when said lid is engaged with said neck portion.
A method of monitoring and optionally controlling the addition of one or more surface additives to a papermaking process comprising the following steps: (a) adding a known amount of a composition containing one or more surface additives to a papermaking process either alone or in known proportion with a known amount of one or more inert fluorescent tracers, wherein the composition containing the surface additives can only be added alone when the surface additives are capable of fluorescing; (b) measuring the fluorescence of the surface additives and/or one or more inert fluorescent tracers in an apparatus that serves to hold or feed or apply an aqueous composition into said papermaking process; (c) measuring the fluorescence of the composition containing the surface additives and/or one or more inert fluorescent tracers at a point subsequent to adding the surface additives and after a sheet has been formed, wherein the surface additives can only be measured when they are capable of fluorescing and wherein fluorescence is measured with a reflectance based fluorometer; (d) correlating the amount of fluorescence of the surface additives when they are capable of fluorescing and/or inert fluorescent tracers with the concentration of the surface additives and then correlating the amount of fluorescence of the surface additives when they are capable of fluorescing and/or inert fluorescent tracers on a sheet with the concentration of the surface additives in a coating on a sheet and/or thickness of a coating on a sheet (a) adding a known amount of a composition containing one or more surface additives to a papermaking process either alone or in known proportion with a known amount of one or more inert fluorescent tracers, wherein the composition containing the surface additives can only be added alone when the surface additives are capable of fluorescing; (b) measuring the fluorescence of the surface additives and/or one or more inert fluorescent tracers in an apparatus that serves to hold or feed or apply an aqueous composition into said papermaking process; (c) measuring the fluorescence of the composition containing the surface additives and/or one or more inert fluorescent tracers at a point subsequent to adding the surface additives and after a sheet has been formed, wherein the surface additives can only be measured when they are capable of fluorescing and wherein fluorescence is measured with a reflectance based fluorometer; (d) correlating the amount of fluorescence of the surface additives when they are capable of fluorescing and/or inert fluorescent tracers with the concentration of the surface additives and then correlating the amount of fluorescence of the surface additives when they are capable of fluorescing and/or inert fluorescent tracers on a sheet with the concentration of the surface additives in a coating on a sheet and/or thickness of a coating on a sheet
An embolic protection device (100, 100') comprising: a first filter comprising a first filter distal end and a first filter proximal end and configured to be disposed in a first vessel; a second filter comprising a second filter distal end and a second filter proximal end and configured to be disposed in a second vessel; a first tether extending from the first filter proximal end; a first magnet coupled to the first tether; a second tether extending from the second filter proximal end; and a second magnet coupled to the second tether, wherein the embolic protection device is configured such that when the first filter is disposed in the first vessel and the second filter is disposed in the second vessel, the first magnet and the second magnet are magnetically coupled to each other to couple the first tether to the second tether. a first filter comprising a first filter distal end and a first filter proximal end and configured to be disposed in a first vessel; a second filter comprising a second filter distal end and a second filter proximal end and configured to be disposed in a second vessel; a first tether extending from the first filter proximal end; a first magnet coupled to the first tether; a second tether extending from the second filter proximal end; and a second magnet coupled to the second tether, wherein the embolic protection device is configured such that when the first filter is disposed in the first vessel and the second filter is disposed in the second vessel, the first magnet and the second magnet are magnetically coupled to each other to couple the first tether to the second tether.
A magnetocardiography arrangement for producing stress magnetocardiograms, comprising a magnetocardiograph and a stress unit consisting of non-magnetic components, wherein the magnetocardiograph and the stress unit are arranged in a shielded chamber for shielding against external magnetic fields, wherein the stress unit is or comprises a bicycle ergometer braked by means of pressurised gas or a pressurised gas mixture from a source for the pressurised gas or the pressurised gas mixture arranged outside the shielded chamber, and wherein the stress unit comprises a flywheel mass rotatable by means of hand or foot actuation via a transmission with a gear ratio of at least 1:10 and a brake unit actuatable by means of the pressurised gas or the pressurised gas mixture for braking the rotation of the flywheel mass, wherein the braking force of the brake unit is adjustable by means of the pressurised gas or the pressurised gas mixture.
A synthesis method of linaclotide, comprising the following steps: 1) preparing a linaclotide precursor resin by reacting Fmoc-Tyr(tBu)-OH with a carrier resin to obtain Fmoc-Tyr(tBu)-resin, and coupling Fmoc-AA-OH one by one in the order from C-terminus to N-terminus with the Fmoc-Tyr(tBu)-resin as a solid phase carrier to obtain the linaclotide precursor resin, wherein the side chains of Cys corresponding to positions 5 and 13 of linaclotide are protected by Me, the side chains of Cys corresponding to positions 1 and 6 of linaclotide are protected by Mmt, and the side chains of Cys corresponding to positions 2 and 10 of linaclotide are protected by Dpm; 2) removing the Mmt protecting groups from the linaclotide precursor resin obtained in step 1) with a deprotecting agent; 3) oxidizing the linaclotide precursor resin obtained in step 2) with an oxidizing agent to form a first disulfide bond to obtain a linaclotide precursor resin containing a mono-dithio ring; 4) cleaving the resin in the linaclotide precursor resin containing a mono-dithio ring obtained in step 3) and simultaneously removing the Dpm protecting groups with a lysing solution to obtain a mono-dithio cyclic peptide; 5) oxidizing the mono-dithio cyclic peptide obtained in step 4) with an oxidizing agent to form a second disulfide bond to obtain a bis-dithio cyclic peptide; and 6) removing the methyl protecting groups of Cys from the bis-dithio cyclic peptide obtained in step 5) and simultaneously oxidizing to form a third disulfide bond with a demethylating and oxidizing agent to obtain the linaclotide. 1) preparing a linaclotide precursor resin by reacting Fmoc-Tyr(tBu)-OH with a carrier resin to obtain Fmoc-Tyr(tBu)-resin, and coupling Fmoc-AA-OH one by one in the order from C-terminus to N-terminus with the Fmoc-Tyr(tBu)-resin as a solid phase carrier to obtain the linaclotide precursor resin, wherein the side chains of Cys corresponding to positions 5 and 13 of linaclotide are protected by Me, the side chains of Cys corresponding to positions 1 and 6 of linaclotide are protected by Mmt, and the side chains of Cys corresponding to positions 2 and 10 of linaclotide are protected by Dpm; 2) removing the Mmt protecting groups from the linaclotide precursor resin obtained in step 1) with a deprotecting agent; 3) oxidizing the linaclotide precursor resin obtained in step 2) with an oxidizing agent to form a first disulfide bond to obtain a linaclotide precursor resin containing a mono-dithio ring; 4) cleaving the resin in the linaclotide precursor resin containing a mono-dithio ring obtained in step 3) and simultaneously removing the Dpm protecting groups with a lysing solution to obtain a mono-dithio cyclic peptide; 5) oxidizing the mono-dithio cyclic peptide obtained in step 4) with an oxidizing agent to form a second disulfide bond to obtain a bis-dithio cyclic peptide; and 6) removing the methyl protecting groups of Cys from the bis-dithio cyclic peptide obtained in step 5) and simultaneously oxidizing to form a third disulfide bond with a demethylating and oxidizing agent to obtain the linaclotide.
A method for removing 4-methylimidazole (4-MEI) from solution, the method comprising: contacting an alkaline earth metal silicate with a solution containing 4-MEI; and adsorbing at least some of the 4-MEI using the alkaline earth metal silicate, wherein the alkaline earth metal silicate comprises less than or equal to 5 wt% of alumina. contacting an alkaline earth metal silicate with a solution containing 4-MEI; and adsorbing at least some of the 4-MEI using the alkaline earth metal silicate, wherein the alkaline earth metal silicate comprises less than or equal to 5 wt% of alumina.
A method for capturing specific cells present in blood or biological fluid, the method comprising: agglutinating blood cells in sampled blood or biological fluid; centrifuging the resulting blood or biological fluid; and then capturing specific cells therefrom onto a hydrophilic polymer layer, the method being carried out in a well wherein the hydrophilic polymer layer is formed on at least a part of the inner surface of the well, wherein the well is a non-through hole. agglutinating blood cells in sampled blood or biological fluid; centrifuging the resulting blood or biological fluid; and then capturing specific cells therefrom onto a hydrophilic polymer layer, the method being carried out in a well wherein the hydrophilic polymer layer is formed on at least a part of the inner surface of the well, wherein the well is a non-through hole.
A method of stepping up the speed of a rotary motion from a first speed, supplied to an input shaft, to a second speed delivered by an output shaft, comprising transmitting said rotary motion from said input shaft, via a drive gear of said input shaft, the drive gear being helical and having a first helix angle (Ψ in), to a layshaft arrangement, so as to generate a first axial thrust of the input shaft in a first axial direction; transmitting said rotary motion from said layshaft arrangement, via a driven gear of said output shaft, said driven gear being helical and having a second helix angle (Ψ out) that is larger than said first helix angle (Ψ in), to said output shaft, so as to generate a second axial thrust of the output shaft in a second direction, said second direction being substantially opposite to said first direction; and applying at least a portion of said first axial thrust and at least a portion of said second axial thrust to the same location of an axially rigid support structure (50; 156), such that said first and second axial thrusts (F1, F2) counter-act and at least partly cancel out in said support structure (50; 156).
A suture anchor comprising: a sleeve having a plurality of threads and defining a longitudinal axis; an elongate member extending from a distal end of the sleeve, along the longitudinal axis; and a tip extending from a distal end of the elongate member, the tip being rigidly coupled to the elongate member; characterised in that: the elongate member is coupled to the sleeve by a break-away coupling; the sleeve, the elongate member, and the tip are rotationally coupled when the break-away coupling is intact; and wherein the sleeve is rotationally decoupled from the elongate member and tip when the break-away coupling is broken. a sleeve having a plurality of threads and defining a longitudinal axis; an elongate member extending from a distal end of the sleeve, along the longitudinal axis; and a tip extending from a distal end of the elongate member, the tip being rigidly coupled to the elongate member; characterised in that: the elongate member is coupled to the sleeve by a break-away coupling; the sleeve, the elongate member, and the tip are rotationally coupled when the break-away coupling is intact; and wherein the sleeve is rotationally decoupled from the elongate member and tip when the break-away coupling is broken. the elongate member is coupled to the sleeve by a break-away coupling; the sleeve, the elongate member, and the tip are rotationally coupled when the break-away coupling is intact; and wherein the sleeve is rotationally decoupled from the elongate member and tip when the break-away coupling is broken.
A device for recovering energy in working machines, with at least one power drive which can be actuated to move a load mass back and forth, and with an energy storage system which absorbs the energy released in the movement of the load mass in one direction and makes it available for subsequent movement in the other direction, an energy storage system being provided in the form of an accumulator cylinder which, mechanically coupled to the load mass, stores pneumatic pressure energy for movement in one direction, and for movement in the other direction acts as an auxiliary working cylinder which supports the power drive and which converts the stored pressure energy into driving force, and the piston rod of the accumulator cylinder forming the piston with a hollow part that is open at the end, characterised in that the inner cavity of the piston is filled with a foam material.
A method for estimating effects of a request to change power usage, the method comprising: receiving, by a power management console at a utility provider, device data about one or more devices from a home area network controller; receiving, by the power management console, user behavior data about the devices; receiving, by the power management console, customer preferences for each of the devices; estimating, by the power management console, the effects of a request to change power usage on a power grid using the device data, the user behavior data and the customer preferences for each of the devices, wherein the estimating the effects of the request to change power usage comprises estimating a change in power consumption associated with the request to change power usage; evaluating suitability of the estimated effects of a request using at least one power consumption goal; and determining whether to send the request to change power usage based on whether the estimated effects are suitable in view of the at least one power consumption goal, wherein the effects of a request to change power usage is estimated before the request to change power usage is sent, and wherein the request to change power usage is sent by a utility provider when sent. receiving, by a power management console at a utility provider, device data about one or more devices from a home area network controller; receiving, by the power management console, user behavior data about the devices; receiving, by the power management console, customer preferences for each of the devices; estimating, by the power management console, the effects of a request to change power usage on a power grid using the device data, the user behavior data and the customer preferences for each of the devices, wherein the estimating the effects of the request to change power usage comprises estimating a change in power consumption associated with the request to change power usage; evaluating suitability of the estimated effects of a request using at least one power consumption goal; and determining whether to send the request to change power usage based on whether the estimated effects are suitable in view of the at least one power consumption goal, wherein the effects of a request to change power usage is estimated before the request to change power usage is sent, and wherein the request to change power usage is sent by a utility provider when sent.
Cryogenic device comprising at least two chambers (120, 130) at two different temperatures, a first chamber at a first temperature T1 accommodating a sample, and a second chamber at a second temperature T2 greater than T1 and being adapted to accommodate a cooling device, said cooling device being adapted to cool wirelines (150, 160) connecting said sample to an external element, wherein said cooling device is a thermalization plate comprising at least one wire-guide having an input for plugging a wire line connected to the sample and an output for plugging a wire line connected to said external element, said wire-guide being thermally connected to the first chamber, characterized in that said thermalization plate is an Insulated Metal Substrate plate.
Bioprinting station comprising: a. a bioprinting device comprising means to deposit a pattern of biological material onto an area of interest of a substrate, said area of interest having a feature that distinguishes said area of interest from a remaining part of the substrate, said Bioprinting device comprising: - at least one biological material dispenser (6, 7, 8) adapted to dispense the biological material to be deposited, and - a positioning system adapted to receive the substrate and to position the area of interest with respect to the dispenser (6, 7, 8), b. an electronic control unit adapted to drive the dispenser (6, 7, 8) and the positioning system relative to one another according to the pattern to be deposited, the Bioprinting station being characterised in that it comprises an imaging system comprising means: - to acquire an image of the substrate and - to reveal on the acquired image the feature of the area of interest with respect to the remaining part,, said imaging system being connected to a control unit comprising means to process the acquired image of the substrate so as to detect the revealed area of interest on the acquired image and to determine the pattern corresponding to the area of interest detected on the acquired image. a. a bioprinting device comprising means to deposit a pattern of biological material onto an area of interest of a substrate, said area of interest having a feature that distinguishes said area of interest from a remaining part of the substrate, said Bioprinting device comprising: - at least one biological material dispenser (6, 7, 8) adapted to dispense the biological material to be deposited, and - a positioning system adapted to receive the substrate and to position the area of interest with respect to the dispenser (6, 7, 8), - at least one biological material dispenser (6, 7, 8) adapted to dispense the biological material to be deposited, and - a positioning system adapted to receive the substrate and to position the area of interest with respect to the dispenser (6, 7, 8), b. an electronic control unit adapted to drive the dispenser (6, 7, 8) and the positioning system relative to one another according to the pattern to be deposited, - to acquire an image of the substrate and - to reveal on the acquired image the feature of the area of interest with respect to the remaining part,,
A fence system for a miter saw, comprising: a fence body including an abutment surface and defining a first slot having a first width, a second slot having a second width, and an aperture; a fixed base including a first bore, a second bore, and a third bore; a first bushing including a first opening and having a first diameter that is substantially equal to the first width, the first bushing extending through the first slot; a second bushing including a second opening and a second diameter that is substantially equal to the second width, the second bushing extending through the second slot; a first fastener extending through the first opening into the first bore and configured to clamp the first bushing to the fixed base; a second fastener extending through the second opening into the second bore and configured to clamp the second bushing to the fixed base; and a third fastener extending through the aperture in the fence body into the third bore, the third fastener being configured to releasably clamp the fence body to the fixed base. a fence body including an abutment surface and defining a first slot having a first width, a second slot having a second width, and an aperture; a fixed base including a first bore, a second bore, and a third bore; a first bushing including a first opening and having a first diameter that is substantially equal to the first width, the first bushing extending through the first slot; a second bushing including a second opening and a second diameter that is substantially equal to the second width, the second bushing extending through the second slot; a first fastener extending through the first opening into the first bore and configured to clamp the first bushing to the fixed base; a second fastener extending through the second opening into the second bore and configured to clamp the second bushing to the fixed base; and a third fastener extending through the aperture in the fence body into the third bore, the third fastener being configured to releasably clamp the fence body to the fixed base.