A computer-implemented method of scaling a state of a production equipment for a production process to produce a chemical, pharmaceutical and/or biotechnological product, the scaling being from a source scale to a target scale, wherein the state is defined by a set of state parameters describing a condition and/or a behaviour of the production equipment, the method comprising: - retrieving mapping information that describes how the state parameters relate to a set of derived parameters; - receiving: -- a source setup specification of a source setup used for executing the production process at the source scale, the source setup specification comprising the source scale value; -- a target setup specification of a target setup used for executing the production process at the target scale, the target setup specification comprising the target scale value; -- a first set of state parameters at the source scale; -- a second set of state parameters at the target scale, wherein at least one of the state parameters at the target scale is a parameter being variable and having no predetermined value at the outset; -- at least one acceptability function defining conditions on the values of the state parameter(s) and/or the values of the derived parameter(s) at the source scale and/or at the target scale; - calculating a first set of derived parameters at the source scale using the first set of state parameters, the source setup specification and the mapping information; - providing an input value for the at least one variable parameter in the second set of state parameters; - calculating a second set of derived parameters at the target scale using the second set of state parameters, the input value, the target setup specification and the mapping information; - comparing the first set of state parameters with the second set of state parameters and/or comparing the first set of derived parameters and the second set of derived parameters; - computing, based on the comparison and on the at least one acceptability function, an acceptability score for the second set of state parameters; - computing an optimal value for the at least one variable parameter by optimising the acceptability score and/or computing an acceptable range for the at least one variable parameter, wherein values within the acceptable range yield an acceptability score above a specific threshold. - retrieving mapping information that describes how the state parameters relate to a set of derived parameters; - receiving: -- a source setup specification of a source setup used for executing the production process at the source scale, the source setup specification comprising the source scale value; -- a target setup specification of a target setup used for executing the production process at the target scale, the target setup specification comprising the target scale value; -- a first set of state parameters at the source scale; -- a second set of state parameters at the target scale, wherein at least one of the state parameters at the target scale is a parameter being variable and having no predetermined value at the outset; -- at least one acceptability function defining conditions on the values of the state parameter(s) and/or the values of the derived parameter(s) at the source scale and/or at the target scale; -- a source setup specification of a source setup used for executing the production process at the source scale, the source setup specification comprising the source scale value; -- a target setup specification of a target setup used for executing the production process at the target scale, the target setup specification comprising the target scale value; -- a first set of state parameters at the source scale; -- a second set of state parameters at the target scale, wherein at least one of the state parameters at the target scale is a parameter being variable and having no predetermined value at the outset; -- at least one acceptability function defining conditions on the values of the state parameter(s) and/or the values of the derived parameter(s) at the source scale and/or at the target scale; - calculating a first set of derived parameters at the source scale using the first set of state parameters, the source setup specification and the mapping information; - providing an input value for the at least one variable parameter in the second set of state parameters; - calculating a second set of derived parameters at the target scale using the second set of state parameters, the input value, the target setup specification and the mapping information; - comparing the first set of state parameters with the second set of state parameters and/or comparing the first set of derived parameters and the second set of derived parameters; - computing, based on the comparison and on the at least one acceptability function, an acceptability score for the second set of state parameters; - computing an optimal value for the at least one variable parameter by optimising the acceptability score and/or computing an acceptable range for the at least one variable parameter, wherein values within the acceptable range yield an acceptability score above a specific threshold.