mhurhangee/ep-ind-claims huggingface dataset:
An instrument port for introducing an instrument into a surgical site, comprising: a port body including a channel running therethrough from a distal end to a proximal end of said port body; an instrument sleeve into which the instrument can be inserted, to provide a custom seal around said instrument, creating an interface between the instrument sleeve and the instrument, the instrument sleeve being in slidable contact with said channel with a gap therebetween; the instrument port further comprising: a fluid flow system for flushing trapped emboli from said instrument port, said fluid flow system including said gap in fluid connection with a fluid inlet and operatively connected to the proximal end of the port body, and a fluid outlet operatively connected to the distal end of the port body, a sealing mechanism to prevent material from entering or exiting the instrument port before the instrument is inserted into the sleeve but to allow access to the surgical site when pushed by an operative end of the instrument, wherein said sealing mechanism reforms a seal once the operative end of the instrument is removed, characterised in that the distal end includes said sealing mechanism. a port body including a channel running therethrough from a distal end to a proximal end of said port body; an instrument sleeve into which the instrument can be inserted, to provide a custom seal around said instrument, creating an interface between the instrument sleeve and the instrument, the instrument sleeve being in slidable contact with said channel with a gap therebetween; the instrument port further comprising: a fluid flow system for flushing trapped emboli from said instrument port, said fluid flow system including said gap in fluid connection with a fluid inlet and operatively connected to the proximal end of the port body, and a fluid outlet operatively connected to the distal end of the port body, a sealing mechanism to prevent material from entering or exiting the instrument port before the instrument is inserted into the sleeve but to allow access to the surgical site when pushed by an operative end of the instrument, wherein said sealing mechanism reforms a seal once the operative end of the instrument is removed, characterised in that the distal end includes said sealing mechanism. a fluid flow system for flushing trapped emboli from said instrument port, said fluid flow system including said gap in fluid connection with a fluid inlet and operatively connected to the proximal end of the port body, and a fluid outlet operatively connected to the distal end of the port body, a sealing mechanism to prevent material from entering or exiting the instrument port before the instrument is inserted into the sleeve but to allow access to the surgical site when pushed by an operative end of the instrument, wherein said sealing mechanism reforms a seal once the operative end of the instrument is removed, characterised in that the distal end includes said sealing mechanism.
A cyclometalated N-heterocyclic carbene complex having one of the following formulae ( I to IV) for use as a medicament for treating cancer: or or a pharmaceutically acceptable salt thereof, wherein, - M is selected from the metal ion of Au 3+ or pt 2+; - X is selected from a carbon atom or a nitrogen atom; - R 1, R 8, R 13, R 18, R 26, and R 29 are each independently selected from the group consisting of -H, - R 2 R 3, R 4, R 5, R 9, R 10, R 14, R 15, R 16, R 17, R 19, R 20, R 21, R 22, R 27, R 28, R 31, and R 32 are each independently selected from the group consisting of -H and -NO 2; or each pair of R 2 and R 3; R 4 and R 5; R 9 and R 10; R 14 and R 15; R 16 and R 17; R 19 and R 20; R 21 and R 22; R 27 and R 28; R 31 and R 32 is independently joined together to form - R 6, R 7, R 11, R 12, R 23, R 24, R 32 and R 33 are each independently selected from the group consisting of -CH 3, -C 2 H 5, -C 3 H 7, -C 4 H 9, -CH 2 OH, -C 2 H 4 OH, -C 3 H 6 OH, -C 4 H 8 OH, - R 25 and R 34 are each independently selected from the group consisting of -CH 2 -, -C 2 H 4 -, -C 3 H 6 - and -C 4 H 8 -; - Each A is independently a pharmaceutically acceptable counter-ion; - n is an integer ranging from 0 to +4; - b is an integer ranging from -4 to -1; - y is equal to the absolute value of n/b when n is >0; and - yA b is absence when n is equal to 0. - M is selected from the metal ion of Au 3+ or pt 2+; - X is selected from a carbon atom or a nitrogen atom; - R 1, R 8, R 13, R 18, R 26, and R 29 are each independently selected from the group consisting of -H, - R 2 R 3, R 4, R 5, R 9, R 10, R 14, R 15, R 16, R 17, R 19, R 20, R 21, R 22, R 27, R 28, R 31, and R 32 are each independently selected from the group consisting of -H and -NO 2; or each pair of R 2 and R 3; R 4 and R 5; R 9 and R 10; R 14 and R 15; R 16 and R 17; R 19 and R 20; R 21 and R 22; R 27 and R 28; R 31 and R 32 is independently joined together to form - R 6, R 7, R 11, R 12, R 23, R 24, R 32 and R 33 are each independently selected from the group consisting of -CH 3, -C 2 H 5, -C 3 H 7, -C 4 H 9, -CH 2 OH, -C 2 H 4 OH, -C 3 H 6 OH, -C 4 H 8 OH, - R 25 and R 34 are each independently selected from the group consisting of -CH 2 -, -C 2 H 4 -, -C 3 H 6 - and -C 4 H 8 -; - Each A is independently a pharmaceutically acceptable counter-ion; - n is an integer ranging from 0 to +4; - b is an integer ranging from -4 to -1; - y is equal to the absolute value of n/b when n is >0; and - yA b is absence when n is equal to 0.
A resin powder for solid freeform fabrication comprising: a particle having a pillar-like form, characterized in that a ratio of a height of the particle to a diameter or a long side of a bottom of the particle is 0.5 to 2.0, characterized in that the particle has a 50 percent cumulative volume particle diameter of from 5 to 200 μm, and characterized in that a ratio (Mv/Mn) of a volume average particle diameter (Mv) to a number average particle diameter (Mn) of the particle is 2.00 or less, wherein the 50 percent cumulative volume particle diameter and Mv/Mn are measured by the method described in the description. a particle having a pillar-like form, characterized in that a ratio of a height of the particle to a diameter or a long side of a bottom of the particle is 0.5 to 2.0, characterized in that the particle has a 50 percent cumulative volume particle diameter of from 5 to 200 μm, and characterized in that a ratio (Mv/Mn) of a volume average particle diameter (Mv) to a number average particle diameter (Mn) of the particle is 2.00 or less, wherein the 50 percent cumulative volume particle diameter and Mv/Mn are measured by the method described in the description.
Protective device for a hand, which comprises precisely two finger protection elements (3, 4) and a palm protection element connecting the two finger protection elements (3, 4), wherein one finger protection element is intended for the thumb and the other finger protection element is intended for a further finger, in particular the index finger, of a user, characterized in that the palm protection element is designed to be planar, so that it only comes into contact with the palm of a user's hand, whereas the back of the user's hand remains free or essentially free, wherein the finger protection elements (3, 4) both lie closer to one end region of the palm protection element than to another end region of the palm protection element opposite the one end region.
A prosthetic valve comprising: a wire frame comprising a generally tubular body portion, an interior area, a longitudinal axis, a first end comprising a plurality of crowns, and a second end comprising a greater number of crowns than the first end, wherein the wire frame comprises a plurality of adjacent rows (20, 21, 22, 23, 24, 25, 26) of modified diamond-shaped structures extending between the first and second ends (12, 14); a valve structure attached within the interior area of the wire frame, the valve structure comprising a plurality of leaflets; wherein the first and second ends (12, 14) of the wire frame each have an outer circumference that is larger than an outer circumference of a central area of the wire frame, wherein the central area is longitudinally spaced between the first and second ends (12, 14); and a plurality of outwardly bulged crowns at the central area of the wire frame. a wire frame comprising a generally tubular body portion, an interior area, a longitudinal axis, a first end comprising a plurality of crowns, and a second end comprising a greater number of crowns than the first end, wherein the wire frame comprises a plurality of adjacent rows (20, 21, 22, 23, 24, 25, 26) of modified diamond-shaped structures extending between the first and second ends (12, 14); a valve structure attached within the interior area of the wire frame, the valve structure comprising a plurality of leaflets; wherein the first and second ends (12, 14) of the wire frame each have an outer circumference that is larger than an outer circumference of a central area of the wire frame, wherein the central area is longitudinally spaced between the first and second ends (12, 14); and a plurality of outwardly bulged crowns at the central area of the wire frame.
Agricultural machine having a data processing device, in particular a job computer, for processing and/or storing machine-relevant information, it being possible for information to be transmitted by the data processing device by means of a wire-free or wired connection to a wirelessly readable electronic unit formed as a tag and arranged on the machine, and the electronic unit having a battery-fed power supply and, in this way, being designed to be wirelessly readable when the agricultural machine is not operating, characterized in that the battery-fed power supply is designed to be chargeable by means of energy harvesting.
Cooling pump, in particular for vehicles, comprising: - a pump body connectable to an intake section of a cooling circuit and to a delivery section of said circuit; - a rotor, housed in the pump body, suitable to take in the liquid from the intake section and to send the pressurised liquid to the delivery section for continuous rotation around a rotation axis; wherein, in the pump body are realized a delivery chamber, positioned downstream of the rotor, and a delivery pipe connected to the delivery chamber, connectable to the delivery section of the cooling circuit; - a valve group positioned between the delivery chamber and the delivery pipe to partialise, in a closed configuration, the passage of the liquid from the delivery chamber to the delivery pipe; wherein the valve group is provided with a through pipe and comprises an obturator, housed in the pipe, so as to swivel around a rotation axis (Y-Y), suitable to obstruct, in a closed configuration, the passage of liquid through the pipe, - drive means suitable to act on the obturator to move it from a closed configuration to an open configuration and vice versa; characterized by the fact that the pump body has a housing compartment and the valve group has a cartridge type structure such that it can be inserted and exctracted from the housing compartment. - a pump body connectable to an intake section of a cooling circuit and to a delivery section of said circuit; - a rotor, housed in the pump body, suitable to take in the liquid from the intake section and to send the pressurised liquid to the delivery section for continuous rotation around a rotation axis; wherein, in the pump body are realized a delivery chamber, positioned downstream of the rotor, and a delivery pipe connected to the delivery chamber, connectable to the delivery section of the cooling circuit; - a valve group positioned between the delivery chamber and the delivery pipe to partialise, in a closed configuration, the passage of the liquid from the delivery chamber to the delivery pipe; wherein the valve group is provided with a through pipe and comprises an obturator, housed in the pipe, so as to swivel around a rotation axis (Y-Y), suitable to obstruct, in a closed configuration, the passage of liquid through the pipe, - drive means suitable to act on the obturator to move it from a closed configuration to an open configuration and vice versa;
A genetically modified mini-pig as a model for studying atherosclerosis, wherein the pig model expresses at least one phenotype associated with atherosclerosis and comprises at least one mutation in the i. endogenous ApoE gene and/or ii. endogenous LDL receptor gene, wherein said at least one phenotype is hypercholesterolemia. i. endogenous ApoE gene and/or ii. endogenous LDL receptor gene,
A process for manufacturing a 5-formyl-pyridine-2,3-dicarboxylic acid ester wherein Z is hydrogen or halogen; Z 1 is hydrogen, halogen, cyano or nitro and R 1, R 2 are independently C 1 -C 10 -alkyl, comprising the steps of (i) reacting a compound of formula, wherein the symbols are as in formula, with a nitrosation agent R 3 -O-N=O wherein R 3 is C 1 -C 8 -alkyl, in the presence of an alkali metal or alkaline earth metal alcoholates or carbonates in a polar aprotic solvent at a temperature of from -45 to 40°C, to obtain an oxime compound where Z, Z 1, R 1 and R 2 are as in formula, and (ii) reacting oxime compound with an aliphatic C 1 -C 10 -aldehyde in the presence of an acid at a temperature in the range of from 0 to 100°C. Z is hydrogen or halogen; Z 1 is hydrogen, halogen, cyano or nitro and R 1, R 2 are independently C 1 -C 10 -alkyl, (i) reacting a compound of formula, wherein the symbols are as in formula, with a nitrosation agent R 3 -O-N=O wherein R 3 is C 1 -C 8 -alkyl, in the presence of an alkali metal or alkaline earth metal alcoholates or carbonates in a polar aprotic solvent at a temperature of from -45 to 40°C, to obtain an oxime compound where Z, Z 1, R 1 and R 2 are as in formula, and (ii) reacting oxime compound with an aliphatic C 1 -C 10 -aldehyde in the presence of an acid at a temperature in the range of from 0 to 100°C.
Spindle drive for adjusting the height of an electrically adjustable steering column, comprising an adjusting spindle rotatably mounted in two bearings, characterised in that - the adjusting spindle comprises two clamping elements (7, 11), which have a centring cone (7', 11') on the sides which face one another, and in that the adjusting spindle is clamped to the two bearings by means of the clamping elements (7, 11) by having the clamping elements (7, 11) bear against the outsides of the centring cones (7', 11'), which are averted from one another, the outsides of the bearings being provided with a mating contour to match the respective centring cone (7', 11'). - the adjusting spindle comprises two clamping elements (7, 11), which have a centring cone (7', 11') on the sides which face one another, and in that the adjusting spindle is clamped to the two bearings by means of the clamping elements (7, 11) by having the clamping elements (7, 11) bear against the outsides of the centring cones (7', 11'), which are averted from one another, the outsides of the bearings being provided with a mating contour to match the respective centring cone (7', 11').
A method at a base station of controlling the transmission of positioning reference signals in a wireless communication network, said method comprising: transmitting positioning reference signals at recurring positioning occasions, for use in making positioning reference signal measurements at receiving radio equipment, wherein each positioning occasion comprises a plurality of consecutive subframes; and muting the positioning reference signals in certain ones of the positioning occasions, according to a muting configuration; and said method characterized by transmitting muting configuration information indicating said muting configuration to a positioning node, wherein the muting configuration information comprises a muting occasion index indicating a positioning occasion to which muting applies within a muting periodicity spanning a plurality of positioning occasions. transmitting positioning reference signals at recurring positioning occasions, for use in making positioning reference signal measurements at receiving radio equipment, wherein each positioning occasion comprises a plurality of consecutive subframes; and muting the positioning reference signals in certain ones of the positioning occasions, according to a muting configuration; and said method characterized by transmitting muting configuration information indicating said muting configuration to a positioning node, wherein the muting configuration information comprises a muting occasion index indicating a positioning occasion to which muting applies within a muting periodicity spanning a plurality of positioning occasions.
A wearable device comprising: at least one lens; a display; at least one sensor (110, 210); and at least one processor, wherein the at least one processor is configured to: identify a level of light sensed through the at least one sensor (110, 210); and control the display to display a notification indicating that the wearable device is in a situation in which the display is capable of being damaged by the light when the level of the light satisfies a preset condition. at least one lens; a display; at least one sensor (110, 210); and at least one processor, wherein the at least one processor is configured to: identify a level of light sensed through the at least one sensor (110, 210); and control the display to display a notification indicating that the wearable device is in a situation in which the display is capable of being damaged by the light when the level of the light satisfies a preset condition. identify a level of light sensed through the at least one sensor (110, 210); and control the display to display a notification indicating that the wearable device is in a situation in which the display is capable of being damaged by the light when the level of the light satisfies a preset condition.
A window shutter unit for external mounting on a building, which window shutter unit comprises a plurality of hollow slats mounted to frame members (3, 4) in a shutter frame, an air outlet opening for delivering ventilation air to a room in the building, and a fresh air inlet system for taking in outside air and conveying the air to the air outlet opening, characterized in that at least a first one of the frame members (3, 4) of the shutter frame is hollow with an interior forming part of a common flow passage leading to the air outlet opening, that the fresh air inlet system comprises air inlet openings in the hollow slats, and a first air flow passage from the individual slat to the common flow passage, which first air flow passage is located at the end of the individual slat and extends to the interior of the first frame member.
An illumination munition 1 comprising a shearable tail unit 2, a main body 5 which comprises a payload cavity 10a for receiving an illumination payload apparatus 10, wherein the payload apparatus is dispensed rearwardly from the main body upon shearing of a shearable thread, a fuze 9, an ogive element 7 located between said main body and the fuze, and an explosive train operably connected to said fuze, wherein the illumination payload apparatus comprises an illumination composition 29, a drogue parachute 27 and a main parachute 28, wherein the main parachute is tethered by a tether arrangement to the illumination payload apparatus, such that after deployment of said main parachute said illumination payload apparatus descends under the control of said main parachute.
Device for machining at least one closure, in particular in a packaging machine, preferably a tubular bag machine, comprising at least one sealing installation for sealing the closure to a packaging material, comprising at least one machining device (21, 22, 33) for machining the closure, at least one infeed for feeding at least one closure to the machining device (21, 22, 33) in a direction of movement, characterized in that at least one drive means (17, 31, 32) is provided for moving the machining device (21, 22, 33) along the direction of movement of the closure during the machining of the closure.
A system for closing the left atrial appendage comprising: a first guide device having a size and length adapted for accessing the left atrial appendage through the vasculature, wherein the first guide device comprises a first alignment member; a second guide device having a size and length adapted for accessing the pericardial space from a subthoracic region, wherein the second guide device comprises a second alignment member; and a closure device comprising an elongate body having a proximal end and a distal end, a closure element, a suture, and a retention member, wherein the closure element and the suture pass through the distal end in a proximal direction and into the retention member in a distal direction, and wherein the closure element comprises a loop defining a continuous aperture therethrough. a first guide device having a size and length adapted for accessing the left atrial appendage through the vasculature, wherein the first guide device comprises a first alignment member; a second guide device having a size and length adapted for accessing the pericardial space from a subthoracic region, wherein the second guide device comprises a second alignment member; and a closure device comprising an elongate body having a proximal end and a distal end, a closure element, a suture, and a retention member, wherein the closure element and the suture pass through the distal end in a proximal direction and into the retention member in a distal direction, and wherein the closure element comprises a loop defining a continuous aperture therethrough.
Assembly (kit) comprising a cosmetic device (applicator), a foundation composition and a corrective composition intended to be applied onto a deposit of the foundation composition by means of said device, the cosmetic device (applicator) comprises an application surface comprising a network of zones having corrective composition releasing properties, which is configured to form during application onto the surface of the foundation composition a pattern, the corrective composition comprises a red dye, the application surface has a peripheral surface comprising islets (42; 120) arranged non-uniformly in the surrounding surface, the said islets (42; 120) each having a largest dimension of at least 0.8 mm and having a shape and/or properties for releasing the corrective composition that are different from the shape and/or properties of the surrounding surface, so as to lead to the creation on the surface of the foundation composition of a pattern whose appearance is linked to the arrangement of the islets (42; 120) on the surface and that reproduces the appearance of skin colour and/or relief heterogeneities.