mhurhangee/ep-ind-claims huggingface dataset:
A compound of Formula I or a pharmaceutically acceptable salt thereof; wherein R 1 is hydrogen, fluoro or hydroxy; R 2 and R 3 are each independently hydrogen or fluoro; X is CR 5 R 6 or O; m is 1 or 2; n is 0, 1 or 2; R 4 is selected from the group consisting of R 5 and R 6 are each independently selected from the group consisting of hydrogen, fluoro, hydroxy, C 1 -C 3 alkyl and C 1 -C 3 alkoxy; R 7 and R 8 are each independently selected from the group consisting of hydrogen, C 1 -C 6 alkyl and C 1 -C 6 alkoxy; wherein the C 1 -C 6 alkyl and C 1 -C 6 alkoxy are optionally substituted with one to three fluoro; and R 9 at each occurrence is independently selected from fluoro, C 1 -C 3 alkyl and C 1 -C 6 alkoxy, wherein the C 1 -C 3 alkyl and C 1 -C 6 alkoxy are optionally substituted with one to three fluoro. or a pharmaceutically acceptable salt thereof; wherein R 1 is hydrogen, fluoro or hydroxy; R 2 and R 3 are each independently hydrogen or fluoro; X is CR 5 R 6 or O; m is 1 or 2; n is 0, 1 or 2; R 4 is selected from the group consisting of R 5 and R 6 are each independently selected from the group consisting of hydrogen, fluoro, hydroxy, C 1 -C 3 alkyl and C 1 -C 3 alkoxy; R 7 and R 8 are each independently selected from the group consisting of hydrogen, C 1 -C 6 alkyl and C 1 -C 6 alkoxy; wherein the C 1 -C 6 alkyl and C 1 -C 6 alkoxy are optionally substituted with one to three fluoro; and R 9 at each occurrence is independently selected from fluoro, C 1 -C 3 alkyl and C 1 -C 6 alkoxy, wherein the C 1 -C 3 alkyl and C 1 -C 6 alkoxy are optionally substituted with one to three fluoro.
A lightweight panel, comprising layers (01, 02, 03, 04) of a rectangular basic shape and bound to one another in a planar manner and each being formed from a multitude of boards, wherein the boards of each layer (01, 02, 03, 04) are laterally bound to one another at their lateral edges and each have a multitude of grooves, which are parallel to one another, on at least one main surface (205, 205'), the boards of a first and of a second layer (01, 02) are oriented at a first acute angle (+α, -α) of between 25 and 60° to the longitudinal lateral edges (200, 200') of the lightweight panel, the boards of the first layer are oriented to the boards of the second layer at an angle (2α) relative to one another, and the lightweight panel in each case has at least one connection groove at at least two longitudinal lateral edges (101, 101'), which are parallel to one another, and one connection spring groove, which is able to cooperate with said lightweight panel in a positive manner, for a, positive connection of congenerous lightweight panels on both sides, characterised in that the boards of at least one layer are laterally bound to one another in a positive manner at their lateral edges via groove and spring, and the boards of at least one layer (01, 02), which is arranged in a central ply, are on both sides (205, 205') or in both main surfaces (205, 205'), respectively, in each case provided with a first and a second multitude of grooves (3, 3'), which intersect one another at angles (γ) of between 5 and 100°, wherein the grooves of each multitude run parallel to one another.
Process for colouring and permanently shaping keratin fibres especially human hair in a single process characterised in that it comprises the following steps a- an aqueous colouring composition based on at least one hair direct dye and not comprising any oxidative dye precursors and/or couplers is applied onto hair and rinsed off from hair with water after processing 1 to 45 min at a temperature of 20 to 45°C and towel dried, b- the towel dried hair is put on curlers, c- an aqueous composition comprising at least one reducing agent is applied onto hair and rinsed off from hair with water after a processing time of 2 to 30 min at ambient temperature and towel dried, d- a composition comprising at least one oxidizing agent is applied onto hair processed for 2 to 15 min and curlers are taken off from hair and optionally rinsed off from hair with water and optionally towel dried, and e- an aqueous colouring composition based on at least one hair direct dye is optionally mixed with a composition comprising at least one oxidizing agent and applied onto hair and rinsed off from hair with water after processing 5 to 45 min at a temperature of 20 to 45°C and towel dried and dried with a dryer or left to dry in the air. a- an aqueous colouring composition based on at least one hair direct dye and not comprising any oxidative dye precursors and/or couplers is applied onto hair and rinsed off from hair with water after processing 1 to 45 min at a temperature of 20 to 45°C and towel dried, b- the towel dried hair is put on curlers, c- an aqueous composition comprising at least one reducing agent is applied onto hair and rinsed off from hair with water after a processing time of 2 to 30 min at ambient temperature and towel dried, d- a composition comprising at least one oxidizing agent is applied onto hair processed for 2 to 15 min and curlers are taken off from hair and optionally rinsed off from hair with water and optionally towel dried, and e- an aqueous colouring composition based on at least one hair direct dye is optionally mixed with a composition comprising at least one oxidizing agent and applied onto hair and rinsed off from hair with water after processing 5 to 45 min at a temperature of 20 to 45°C and towel dried and dried with a dryer or left to dry in the air.
A method of assembly of two sheet metal elements (1, 2), one of which is made of steel and the other of aluminium, including a thermal welding step of the two sheet metal elements using a filler material, characterized in that a V-shaped joining face is arranged between the two sheet metal elements (1, 2), the two sheet metal elements (1, 2) are fixed by depositing a weld bead in the base of the joining face in a discontinuous manner along said joining face, then a material suitable for forming a sealed joint over the entire length of said joining face is deposited in the joining face.
An apparatus for controlling a virtual engine sound in response to auto-cruise speed settings, comprising: a controller area network communication unit configured to receive information on auto-cruise speed settings and whether an auto-cruise function is activated, and generate a CAN signal, wherein the CAN communication unit is configured to enable the CAN signal in the case that the auto-cruise function is not activated and the case that the auto-cruise function is activated and a driver changes the auto-cruise speed settings, and wherein the CAN communication unit is configured to disable the CAN signal when the auto-cruise function is activated and a driver does not change the auto-cruise speed settings; a control unit configured to control a virtual engine sound function in response to the CAN signal; a signal processing unit configured to process and output a virtual engine sound signal according to control of the control unit, wherein the control unit is configured to control the signal processing unit to not output the virtual engine sound signal, when the CAN signal is disabled, and to output the virtual engine sound signal, when the CAN signal is enabled; and a digital amp unit configured to amplify the virtual engine sound signal outputted from the signal processing unit and produce a virtual engine sound. a controller area network communication unit configured to receive information on auto-cruise speed settings and whether an auto-cruise function is activated, and generate a CAN signal, wherein the CAN communication unit is configured to enable the CAN signal in the case that the auto-cruise function is not activated and the case that the auto-cruise function is activated and a driver changes the auto-cruise speed settings, and wherein the CAN communication unit is configured to disable the CAN signal when the auto-cruise function is activated and a driver does not change the auto-cruise speed settings; a control unit configured to control a virtual engine sound function in response to the CAN signal; a signal processing unit configured to process and output a virtual engine sound signal according to control of the control unit, wherein the control unit is configured to control the signal processing unit to not output the virtual engine sound signal, when the CAN signal is disabled, and to output the virtual engine sound signal, when the CAN signal is enabled; and a digital amp unit configured to amplify the virtual engine sound signal outputted from the signal processing unit and produce a virtual engine sound.
A plug comprising: a plurality of first pins to make electrically conductive paths with a plurality of second pins in a receptacle when the plug is mated with the receptacle; and a plurality of magnets (380, 381, 382, 383), the plurality of magnets (380, 381, 382, 383) to mate with an attraction plate made of ferromagnetic material in the receptacle, wherein the plurality of magnets (380, 381, 382, 383) are arranged in opposing polarities with respect to each other so that when the receptacle is brought in close proximity to the plug, magnetic field lines travel through the attraction plate of the receptacle from one of the plurality of magnets (380, 381, 382, 383) in the plug to another one of the plurality of magnets (380, 381, 382, 383) in the plug, wherein the plurality of magnets (380, 381, 382, 383) are arranged such that they leave an opening for the electrically conductive paths of the plurality of first pins with the plurality of second pins, characterised in that the first pins are biased. a plurality of first pins to make electrically conductive paths with a plurality of second pins in a receptacle when the plug is mated with the receptacle; and a plurality of magnets (380, 381, 382, 383), the plurality of magnets (380, 381, 382, 383) to mate with an attraction plate made of ferromagnetic material in the receptacle, wherein the plurality of magnets (380, 381, 382, 383) are arranged in opposing polarities with respect to each other so that when the receptacle is brought in close proximity to the plug, magnetic field lines travel through the attraction plate of the receptacle from one of the plurality of magnets (380, 381, 382, 383) in the plug to another one of the plurality of magnets (380, 381, 382, 383) in the plug, wherein the plurality of magnets (380, 381, 382, 383) are arranged such that they leave an opening for the electrically conductive paths of the plurality of first pins with the plurality of second pins, characterised in that the first pins are biased.
An exercise device for exercising a joint and a limb comprising: an actuation member rotatable about a rotation axis, the actuation member including a first portion and a second portion, the second portion is movable in a direction perpendicular to the rotation axis; a first load cell having a first end mounted to the second portion and a second end mounted to a support member, the first load cell configured to measure force between the support member and the actuation member; a foot plate at a distal end of the second portion of the actuation member; a foot plate load cell mounted to the foot plate, the foot plate load cell configured to measure force exerted on the foot plate in a direction away from the rotation axis; and a restrictor configured to restrict movement of the second portion of the actuation member and the foot plate at the distal end thereof in the direction perpendicular to the rotation axis unless force exerted on the foot plate exceeds a predetermined force. an actuation member rotatable about a rotation axis, the actuation member including a first portion and a second portion, the second portion is movable in a direction perpendicular to the rotation axis; a first load cell having a first end mounted to the second portion and a second end mounted to a support member, the first load cell configured to measure force between the support member and the actuation member; a foot plate at a distal end of the second portion of the actuation member; a foot plate load cell mounted to the foot plate, the foot plate load cell configured to measure force exerted on the foot plate in a direction away from the rotation axis; and a restrictor configured to restrict movement of the second portion of the actuation member and the foot plate at the distal end thereof in the direction perpendicular to the rotation axis unless force exerted on the foot plate exceeds a predetermined force.
An apparatus, comprising: a disc-shaped valve plug including a first metallic sealing surface extending circumferentially about a peripheral edge of the valve plug, the first metallic sealing surface having a first curved profile; and a valve seat defining an orifice and including a second metallic sealing surface having a second curved profile, the first and second profiles being complementary so that the first and second metallic sealing surfaces (406, 408) form a seal when the first and second metallic sealing surfaces (406, 408) are in contact; and characterized in that the apparatus comprises a spring seat coupled to the valve plug via suitable fasteners positioned within bores of the valve plug. a disc-shaped valve plug including a first metallic sealing surface extending circumferentially about a peripheral edge of the valve plug, the first metallic sealing surface having a first curved profile; and a valve seat defining an orifice and including a second metallic sealing surface having a second curved profile, the first and second profiles being complementary so that the first and second metallic sealing surfaces (406, 408) form a seal when the first and second metallic sealing surfaces (406, 408) are in contact; and characterized in that the apparatus comprises a spring seat coupled to the valve plug via suitable fasteners positioned within bores of the valve plug.
Process for upgrading a heavy hydrocarbonaceous feedstock in at least one hydroconversion reactor for hydroconversion of said heavy hydrocarbonaceous feedstock and in at least one hydrotreatment reactor for hydrotreatment of said heavy hydrocarbonaceous feedstock, said process comprising the preparation of two or more catalysts, each catalyst being prepared from one or more catalyst precursors in at least one specific preparation reactor, said catalyst precursors containing at least one transition metal selected from group IIA, IIIB, IVB, VB, VIB, VIIB, VIII, IB or IIB of the periodic table of elements, and each preparation reactor feeding one or more hydroconversion or hydrotreatment reactors, each catalyst contained in a preparation reactor being dedicated to hydroconversion or hydrotreatment of said feedstock and wherein the catalyst dedicated to hydroconversion contains Mo, in an active state, and catalyst(s) dedicated to hydrotreatment contain(s) two transition metals in an active state, Mo and Ni or Mo and V, or Fe and Ni, and the catalyst precursor of said catalyst dedicated to hydroconversion is (C 5 H 5) 2 MoCl 2.
A stable, natural blue colorant obtainable from a process comprising the steps: (a) forming a mixture comprising (i) a first component, wherein said first component is the juice from the fruit of Huito, Genipa americana, wherein said juice contains sufficient genepin or derivatives of genepin, including genepin gentiobioside, geniposide, geniposidic acid, and gardenoside, capable of reacting with other compounds to produce a colored product; (ii) a second component, wherein said second component is an edible material selected to provide other components resulting in the desired color, and wherein said second component comprises nitrogenous compounds selected from the group consisting of amino acids, polypeptides, proteins, compounds with one or more primary amine groups, and combinations thereof; (b) co-processing said mixture at a pH in the range of 3 to 8; and (c) applying a heat treatment sufficient to stabilize the mixture against microbial growth, oxidation, organoleptic deterioration and provide color intensity. (a) forming a mixture comprising (i) a first component, wherein said first component is the juice from the fruit of Huito, Genipa americana, wherein said juice contains sufficient genepin or derivatives of genepin, including genepin gentiobioside, geniposide, geniposidic acid, and gardenoside, capable of reacting with other compounds to produce a colored product; (ii) a second component, wherein said second component is an edible material selected to provide other components resulting in the desired color, and wherein said second component comprises nitrogenous compounds selected from the group consisting of amino acids, polypeptides, proteins, compounds with one or more primary amine groups, and combinations thereof; (i) a first component, wherein said first component is the juice from the fruit of Huito, Genipa americana, wherein said juice contains sufficient genepin or derivatives of genepin, including genepin gentiobioside, geniposide, geniposidic acid, and gardenoside, capable of reacting with other compounds to produce a colored product; (ii) a second component, wherein said second component is an edible material selected to provide other components resulting in the desired color, and wherein said second component comprises nitrogenous compounds selected from the group consisting of amino acids, polypeptides, proteins, compounds with one or more primary amine groups, and combinations thereof; (b) co-processing said mixture at a pH in the range of 3 to 8; and (c) applying a heat treatment sufficient to stabilize the mixture against microbial growth, oxidation, organoleptic deterioration and provide color intensity.
An apparatus comprising: a silicon substrate; a PMOS device on the silicon substrate including a gate electrode on a surface in an area of the silicon substrate defined by a N-type well; a single crystal silicon germanium alloy material disposed in each of a first junction region and a second junction region in the silicon substrate adjacent the gate electrode of the PMOS device, wherein (a) a lattice spacing of the silicon germanium alloy material is different than a lattice spacing of a material of the N-type well of the silicon substrate and (b) a surface of the first junction region and a surface of the second junction region are in a non-planar relationship with the surface of the silicon substrate; a NMOS device complementary to the PMOS device and comprising junction regions defined by doped portions of a material of a P-type well of the silicon substrate, the NMOS device having a gate electrode and spacers along sidewalls of the gate electrode; an STI structure adjacent the NMOS device; and an etch stop layer conformally disposed on the silicon substrate along the spacers of the NMOS device, on the junction regions of the NMOS device, and on the STI structure, the etch stop layer exclusive of the gate electrode of the PMOS device, wherein the etch stop layer causes tensile stress in the NMOS device. a silicon substrate; a PMOS device on the silicon substrate including a gate electrode on a surface in an area of the silicon substrate defined by a N-type well; a single crystal silicon germanium alloy material disposed in each of a first junction region and a second junction region in the silicon substrate adjacent the gate electrode of the PMOS device, wherein (a) a lattice spacing of the silicon germanium alloy material is different than a lattice spacing of a material of the N-type well of the silicon substrate and (b) a surface of the first junction region and a surface of the second junction region are in a non-planar relationship with the surface of the silicon substrate; a NMOS device complementary to the PMOS device and comprising junction regions defined by doped portions of a material of a P-type well of the silicon substrate, the NMOS device having a gate electrode and spacers along sidewalls of the gate electrode; an STI structure adjacent the NMOS device; and an etch stop layer conformally disposed on the silicon substrate along the spacers of the NMOS device, on the junction regions of the NMOS device, and on the STI structure, the etch stop layer exclusive of the gate electrode of the PMOS device, wherein the etch stop layer causes tensile stress in the NMOS device.
A polymeric microneedle array for delivery of macromolecular compounds through the skin having a plurality of micro-scaled solid microneedles, the microneedles consisting of a dried polymer composition comprising: 15 to 40 wt.% of a water soluble polymer as a binder, less than 2 wt.% of a humectant/softener, and less than 2 wt.% of a surfactant; and 1 to 15 wt.% of the macromolecular compound encapsulated therein, wherein the wt.% are given with respect to the liquid polymer composition before drying. 15 to 40 wt.% of a water soluble polymer as a binder, less than 2 wt.% of a humectant/softener, and less than 2 wt.% of a surfactant; and 1 to 15 wt.% of the macromolecular compound encapsulated therein,
A navigation device comprising: a processor that is configured to generate a navigation map of a local environment; an input device connected to the processor and configured to receive information from a user to display the location of points of interest; a display controllable by said processor to display said navigation map and a marker on said navigation map for any of said points of interest within said local environment; and an indicator generation module for generating an indicator for one or more of said points of interest outside of said local environment, said processor being responsive to said indicator generation module to control said display to display any generated indicators, and wherein the indicator generation module is configured to populate the indicator with a plurality of information elements comprising: a representation of the distance between the navigation map and the point of interest; and an icon representative of the type of the point of interest. a processor that is configured to generate a navigation map of a local environment; an input device connected to the processor and configured to receive information from a user to display the location of points of interest; a display controllable by said processor to display said navigation map and a marker on said navigation map for any of said points of interest within said local environment; and an indicator generation module for generating an indicator for one or more of said points of interest outside of said local environment,
A drive unit for a vehicle comprising: an electric motor; a brake sensor detecting a braking operation amount; and a controller; characterized in that the drive unit further comprises a torque converter to which a torque outputted from the motor is inputted and in that the controller is configured for executing a first control of controlling the torque outputted from the motor based on the braking operation amount such that, even during stop of the vehicle, the motor can be kept rotated. an electric motor; a brake sensor detecting a braking operation amount; and a controller; characterized in that the drive unit further comprises a torque converter to which a torque outputted from the motor is inputted and in that the controller is configured for executing a first control of controlling the torque outputted from the motor based on the braking operation amount such that, even during stop of the vehicle, the motor can be kept rotated.