mhurhangee/ep-ind-claims huggingface dataset:
A compound of Formula la: or a stereoisomer, tautomer, pharmaceutically acceptable salt, or hydrate thereof, wherein: R 1a is selected from the following structures: which may be optionally substituted with 1 to 3 groups selected from R 4; R 2 is (a) selected from bicyclic aryl and bicyclic heteroaryl groups optionally substituted with 1 to 5 R 5 groups; or (b) selected from the following structures: which may be optionally substituted with 1 to 2 groups selected from alkyl (C 1 -C 6), halogen, ketone, amide, and ester; R 3 is selected from the following structures: each of which may be optionally substituted with 1 to 5 groups selected from R 5; each R 4 is independently selected from deuterium, alkyl (C 1 -C 6), cycloalkyl (C 3 -C 8), alkoxy (C 1 -C 6), amino, -NHC NH-alkyl(C 1 -C 6), halogen, amide, -CF 3, -CN, -N 3, ketone, -S -alkyl(C 1 -C 4), -SO 2 -alkyl(C 1 -C 6), thioalkyl(C 1 -C 6), -COOH, and ester, each of which may be optionally substituted with hydrogen, F, Cl, Br, -OH, -NH 2, -NHMe, -OMe, -SMe, oxo, and/or thio-oxo; and each R 5 is independently selected from deuterium, alkyl (C 1 -C 6), alkoxy (C 1 -C 6), amino, -NHC NH-alkyl(C 1 -C 6), halogen, amide, -CF 3, -CN, -N 3, ketone (C 1 -C 6), -S -alkyl(C 1 -C 4), -SO 2 -alkyl(C 1 -C 6), thioalkyl(C 1 -C 6), -COOH, and ester, each of which may be optionally substituted with hydrogen, F, Cl, Br, -OH, -NH 2, -NHMe, -OMe, -SMe, oxo, and/or thio-oxo. R 1a is selected from the following structures: which may be optionally substituted with 1 to 3 groups selected from R 4; R 2 is (a) selected from bicyclic aryl and bicyclic heteroaryl groups optionally substituted with 1 to 5 R 5 groups; or (b) selected from the following structures: which may be optionally substituted with 1 to 2 groups selected from alkyl (C 1 -C 6), halogen, ketone, amide, and ester; (a) selected from bicyclic aryl and bicyclic heteroaryl groups optionally substituted with 1 to 5 R 5 groups; or (b) selected from the following structures: which may be optionally substituted with 1 to 2 groups selected from alkyl (C 1 -C 6), halogen, ketone, amide, and ester; R 3 is selected from the following structures: each of which may be optionally substituted with 1 to 5 groups selected from R 5; each R 4 is independently selected from deuterium, alkyl (C 1 -C 6), cycloalkyl (C 3 -C 8), alkoxy (C 1 -C 6), amino, -NHC NH-alkyl(C 1 -C 6), halogen, amide, -CF 3, -CN, -N 3, ketone, -S -alkyl(C 1 -C 4), -SO 2 -alkyl(C 1 -C 6), thioalkyl(C 1 -C 6), -COOH, and ester, each of which may be optionally substituted with hydrogen, F, Cl, Br, -OH, -NH 2, -NHMe, -OMe, -SMe, oxo, and/or thio-oxo; and each R 5 is independently selected from deuterium, alkyl (C 1 -C 6), alkoxy (C 1 -C 6), amino, -NHC NH-alkyl(C 1 -C 6), halogen, amide, -CF 3, -CN, -N 3, ketone (C 1 -C 6), -S -alkyl(C 1 -C 4), -SO 2 -alkyl(C 1 -C 6), thioalkyl(C 1 -C 6), -COOH, and ester, each of which may be optionally substituted with hydrogen, F, Cl, Br, -OH, -NH 2, -NHMe, -OMe, -SMe, oxo, and/or thio-oxo.
A method of making a high strength head-hardened crane rail comprising the steps of: providing a crane steel rail having a composition comprising, in weight percent: carbon 0.79 - 1.00%; manganese 0.40 - 1.00; silicon 0.30 - 1.00; chromium 0.20 - 1.00; vanadium 0.05 - 0.35; titanium 0.01 - 0.035; nitrogen 0.002 to 0.0150; and the remainder being predominantly iron, said crane steel rail provided at a temperature between 700 and 800 oC; cooling said crane steel rail at a cooling rate that, if plotted on a graph with xy-coordinates with the x-axis representing cooling time in seconds and the y-axis representing temperature in oC of the surface of the head of the crane steel rail, is maintained in a region between an upper cooling rate boundary plot defined by an upper line connecting xy-coordinates (0 s, 800 oC), (40 s, 700 oC), and (140 s, 600 oC) and a lower cooling rate boundary plot defined by a lower line connecting xy-coordinates (0 s, 700 oC), (40 s, 600 oC), and (140 s, 500 oC), and wherein the cooling rate from 0 second to 20 seconds plotted on the graph has an average within a range of between 2.25 oC/sec and 5 oC/sec, and the cooling rate from 20 seconds to 140 seconds plotted on the graph has an average within a range of between 1 oC/sec and 1.5 oC/sec; wherein said step of cooling said crane steel rail comprises cooling said rail with water for 140 seconds and further comprises the step of cooling said rail in air to ambient temperature after said step of cooling said rail with water for 140 seconds. providing a crane steel rail having a composition comprising, in weight percent: carbon 0.79 - 1.00%; manganese 0.40 - 1.00; silicon 0.30 - 1.00; chromium 0.20 - 1.00; vanadium 0.05 - 0.35; titanium 0.01 - 0.035; nitrogen 0.002 to 0.0150; and the remainder being predominantly iron, said crane steel rail provided at a temperature between 700 and 800 oC; cooling said crane steel rail at a cooling rate that, if plotted on a graph with xy-coordinates with the x-axis representing cooling time in seconds and the y-axis representing temperature in oC of the surface of the head of the crane steel rail, is maintained in a region between an upper cooling rate boundary plot defined by an upper line connecting xy-coordinates (0 s, 800 oC), (40 s, 700 oC), and (140 s, 600 oC) and a lower cooling rate boundary plot defined by a lower line connecting xy-coordinates (0 s, 700 oC), (40 s, 600 oC), and (140 s, 500 oC), and wherein the cooling rate from 0 second to 20 seconds plotted on the graph has an average within a range of between 2.25 oC/sec and 5 oC/sec, and the cooling rate from 20 seconds to 140 seconds plotted on the graph has an average within a range of between 1 oC/sec and 1.5 oC/sec; wherein said step of cooling said crane steel rail comprises cooling said rail with water for 140 seconds and further comprises the step of cooling said rail in air to ambient temperature after said step of cooling said rail with water for 140 seconds.
Piston device for a forming and filling station for forming a preform into a container and filling said container using a pressurized liquid, said piston device comprising: - an inlet through which said device can receive liquid; - an outlet through which said device can inject said pressurize liquid; - a main body defining an inner chamber and an upstream duct placing the inner chamber in fluidic communication with the inlet; - an injection piston movable inside the inner chamber separating the inner chamber in an active portion and in a complementary portion, said injection piston isolating the active portion from the complementary portion, said active portion being in fluidic communication with both the upstream duct and the outlet, characterised by - a valve comprising a valve plate movable along a plate actuation path, comprising at least an opened position of the plate, wherein liquid is allowed to flow inside the active portion of the inner chamber from the inlet, and a closed position of the plate, wherein liquid is prevented from flowing from said active portion into the inlet, and the plate actuation path extending at least in part inside the upstream duct, wherein the valve plate is applied in a fluid tight manner against a valve seat in the closed position of the plate, said valve seat having a central bore forming the inlet of the piston device, the valve plate extending between said valve seat and said inner chamber such that, when the active portion of the inner chamber is filled with liquid and the injection piston moves to reduce the volume of the active portion, a force applied by the liquid urges the valve plate against the valve seat. - an inlet through which said device can receive liquid; - an outlet through which said device can inject said pressurize liquid; - a main body defining an inner chamber and an upstream duct placing the inner chamber in fluidic communication with the inlet; - an injection piston movable inside the inner chamber separating the inner chamber in an active portion and in a complementary portion, said injection piston isolating the active portion from the complementary portion, said active portion being in fluidic communication with both the upstream duct and the outlet, - a valve comprising a valve plate movable along a plate actuation path, comprising at least an opened position of the plate, wherein liquid is allowed to flow inside the active portion of the inner chamber from the inlet, and a closed position of the plate, wherein liquid is prevented from flowing from said active portion into the inlet,
A multi-stage heat exchange system, characterized in that the multi-stage heat exchange system comprises: a first stage heat exchange rack comprising one or more open-flow plates (1022, 1051, 1052, 1905, 1910, 2005, 2010) in fluid communication with a first working fluid flowing through an internal passage in each of the one or more open-flow plates; a second stage heat exchange rack vertically aligned with the first heat exchange rack, the second stage heat exchange rack comprising one or more open-flow plates (1022, 1051, 1052, 1905, 1910, 2005, 2010) in fluid communication with a second working fluid flowing through an internal passage in each of the one or more open-flow plates; wherein a non-working fluid flows first through the first stage heat exchange rack and around each of the one or more open-flow plates therein for thermal exchange with the first working fluid and secondly through the second heat exchange rack and around each of the open-flow plates for thermal exchange with the second working fluid. a first stage heat exchange rack comprising one or more open-flow plates (1022, 1051, 1052, 1905, 1910, 2005, 2010) in fluid communication with a first working fluid flowing through an internal passage in each of the one or more open-flow plates; a second stage heat exchange rack vertically aligned with the first heat exchange rack, the second stage heat exchange rack comprising one or more open-flow plates (1022, 1051, 1052, 1905, 1910, 2005, 2010) in fluid communication with a second working fluid flowing through an internal passage in each of the one or more open-flow plates; wherein a non-working fluid flows first through the first stage heat exchange rack and around each of the one or more open-flow plates therein for thermal exchange with the first working fluid and secondly through the second heat exchange rack and around each of the open-flow plates for thermal exchange with the second working fluid.
Method for using a device for controlling a driving light of a vehicle, which - consists of two headlamps (1.1, 1.2), these being a left headlamp (1.1) and a right headlamp (1.2), wherein - each of the headlamps (1.1, 1.2) comprises at least one pivotable optical element for generating a light image and/or a driving light distribution, wherein - the respective optical element is a roller (1.1.1, 1.2.1) and several light passage structures are applied to or incorporated into the roller (1.1.1, 1.2.1) for generating various light images and/or driving light distributions, and - wherein the roller (1.1.1) for the left headlamp (1.1) differs from the roller (1.2.1) for the right headlamp (1.2) in at least one light passage structure, characterised in that - a collision risk with an unlit object is detected, - wherein on detection of a collision risk with the unlit object a special function of the driving light is activated, wherein - a limited light area directed onto the unlit object in front of the vehicle is generated with a light passage structure in the form of a light passage opening of the roller (1.1.1) of the left headlamp (1.1), wherein means for the horizontal pivoting of a light distribution (L1, L2) are used for pivoting the limited light area onto the unlit object. and - a light image and/or a driving light distribution such as dipped beam or main beam of part-main beam is generated by means of the roller (1.2.1) of the right headlamp (1.2) as a function of an oncoming or preceding vehicle. - consists of two headlamps (1.1, 1.2), these being a left headlamp (1.1) and a right headlamp (1.2), wherein - each of the headlamps (1.1, 1.2) comprises at least one pivotable optical element for generating a light image and/or a driving light distribution, wherein - the respective optical element is a roller (1.1.1, 1.2.1) and several light passage structures are applied to or incorporated into the roller (1.1.1, 1.2.1) for generating various light images and/or driving light distributions, and - wherein the roller (1.1.1) for the left headlamp (1.1) differs from the roller (1.2.1) for the right headlamp (1.2) in at least one light passage structure, - a collision risk with an unlit object is detected, - wherein on detection of a collision risk with the unlit object a special function of the driving light is activated, wherein - a limited light area directed onto the unlit object in front of the vehicle is generated with a light passage structure in the form of a light passage opening of the roller (1.1.1) of the left headlamp (1.1), wherein means for the horizontal pivoting of a light distribution (L1, L2) are used for pivoting the limited light area onto the unlit object. and - a light image and/or a driving light distribution such as dipped beam or main beam of part-main beam is generated by means of the roller (1.2.1) of the right headlamp (1.2) as a function of an oncoming or preceding vehicle.
Method of manufacturing a bumper back beam, the bumper back beam being equipped with a fiber composite reinforcing material (35, 36, 37, 38, 39, 40, 41) with hollow section inside, and comprising, a body formed with a synthetic resin, and a fiber composite reinforcing material (35, 36, 37, 38, 39, 40, 41) with hollow section that is fastened inside the body, wherein the bumper back beam, as being built inside a bumper cover, reduces impact coming in from outside the method comprising manufacturing the fiber composite reinforcing material (35, 36, 37, 38, 39, 40, 41) by mixing and melting a glass fiber or carbon fiber based continuous fiber with a synthetic resin, followed by extruding and pressing, positioning the previously manufactured fiber composite reinforcing material inside an injection mold, and further injecting a synthetic resin in a melting state inside a mold, wherein the fiber composite reinforcing material comprises 60 weight% to 70 weight% of a continuous fiber, and 30 weight% to 40 weight% of a synthetic resin, and wherein the fiber composite reinforcing material comprises a main part being housed entirely inside the body through insert injection molding and providing stiffness outward, and a connecting part having a stripe shape with constant width and thickness and being formed to be integrated into a side of the main part.
A method for decoding a signal, comprising: receiving a bitstream comprising an encoded bitstream of a low frequency signal, an adaptively encoded bitstream of a high frequency signal, and a result of a classification decision process; wherein the result of the classification decision process determines a current frame type of the high frequency signal, wherein, the types of the high frequency signals include a transient signal and a non-transient signal; allocating bits according to the current frame type of the high frequency signal; wherein, according to the result of the classification decision process, values of M1=16,N1=16, or M2=32, N2=0 are selected to allocate bits, and a time envelope and a spectral envelope are decoded by using the allocated bits; M1 represents bits occupied by the time envelope of the transient signal, N1 represents bits occupied by the spectral envelope of the transient signal; M2 represents bits occupied by the spectral envelope of the non-transient signal, N2 represents bits occupied by the time envelope of the non-transient signal; adaptively decoding the time envelope and the spectral envelope of the current frame of the high frequency signal according to a determined excitation signal by using the allocated bits; and obtaining an output signal comprising a decoded low frequency signal and the adaptively decoded high frequency signal; wherein the method further comprises: determining the excitation signal according to the result of the classification decision process and the decoded low frequency signal. receiving a bitstream comprising an encoded bitstream of a low frequency signal, an adaptively encoded bitstream of a high frequency signal, and a result of a classification decision process; wherein the result of the classification decision process determines a current frame type of the high frequency signal, wherein, the types of the high frequency signals include a transient signal and a non-transient signal; allocating bits according to the current frame type of the high frequency signal; wherein, according to the result of the classification decision process, values of M1=16,N1=16, or M2=32, N2=0 are selected to allocate bits, and a time envelope and a spectral envelope are decoded by using the allocated bits; M1 represents bits occupied by the time envelope of the transient signal, N1 represents bits occupied by the spectral envelope of the transient signal; M2 represents bits occupied by the spectral envelope of the non-transient signal, N2 represents bits occupied by the time envelope of the non-transient signal; adaptively decoding the time envelope and the spectral envelope of the current frame of the high frequency signal according to a determined excitation signal by using the allocated bits; and obtaining an output signal comprising a decoded low frequency signal and the adaptively decoded high frequency signal; wherein the method further comprises: determining the excitation signal according to the result of the classification decision process and the decoded low frequency signal.
Lightweight façade module having a frame formed from frame profiles, an outer membrane arranged on the outer side of the frame profiles and an inner membrane arranged on the inner side of the frame profiles, characterised in that the frame profiles are configured in one piece or consist of an outer profile and an inner profile connected to the latter via insulating bars and in that the outer membrane and the inner membrane are attached to the frame profiles by releasably attached clamping elements arranged positively in recesses on the outer side and inner side of the frame profiles.
A medicine supply apparatus that subdivides and supplies medicines, comprising: a cassette unit that is provided movably between a fixed position where the medicines can be supplied and a drawn position displaced from the fixed position, and can temporarily retain the medicines in a subdivided manner; a cover provided movably between a closed position to cover the cassette unit from above and an opened position where the cassette unit is exposed when the cassette unit is held at the fixed position; and an association mechanism that associates operations of the cassette unit and the cover, wherein the association mechanism restricts the operation of the cassette unit so as to keep the cassette unit at the fixed position when the cover is held at the opened position. a cassette unit that is provided movably between a fixed position where the medicines can be supplied and a drawn position displaced from the fixed position, and can temporarily retain the medicines in a subdivided manner; a cover provided movably between a closed position to cover the cassette unit from above and an opened position where the cassette unit is exposed when the cassette unit is held at the fixed position; and an association mechanism that associates operations of the cassette unit and the cover, wherein the association mechanism restricts the operation of the cassette unit so as to keep the cassette unit at the fixed position when the cover is held at the opened position.
A time synchronization system including at least one time server and a plurality of time clients (101a, 101b) connected to each other via a network, the time server comprising: communication means configured to transmit time information of an internal timepiece upon receiving a message transmitted from one of the plurality of time clients (101a, 101b); and time count control means configured to, when a plurality of messages are received from the plurality of time clients (101a, 101b) within a predetermined time, output, via the communication means, collision estimation information generated with respect to a message received from one of the plurality of time clients (101a, 101b) which was received later, and each of the time clients (101a, 101b) comprising time count control means configured to synchronize time information of an internal timepiece with time information of the time server which is obtained by transmitting a message to, and receiving a message from, the time server, and wherein the time count control means of each of the plurality of time clients (101a, 101b) is configured to adjust transmission intervals between transmission of the messages to the time server to be irregular intervals and configured to control transmission of the messages to the time server upon receiving the collision estimation information. communication means configured to transmit time information of an internal timepiece upon receiving a message transmitted from one of the plurality of time clients (101a, 101b); and time count control means configured to, when a plurality of messages are received from the plurality of time clients (101a, 101b) within a predetermined time, output, via the communication means, collision estimation information generated with respect to a message received from one of the plurality of time clients (101a, 101b) which was received later, and each of the time clients (101a, 101b) comprising time count control means configured to synchronize time information of an internal timepiece with time information of the time server which is obtained by transmitting a message to, and receiving a message from, the time server, and wherein the time count control means of each of the plurality of time clients (101a, 101b) is configured to adjust transmission intervals between transmission of the messages to the time server to be irregular intervals and configured to control transmission of the messages to the time server upon receiving the collision estimation information.