A waterproof and vapor-permeable shoe, comprising: - a bottom shoe part (11, 111, 211, 311, 411, 511), which comprises a sole (12, 112, 212, 312, 412, 512) that is perforated through from the tread toward the foot resting region, - a top part (13, 113, 213, 313, 413, 513), which surrounds the foot completely and in turn comprises, from the inside outwardly: - a vapor-permeable or perforated lining (14, 114, 214, 314, 414,514), - a membrane (15, 115, 215, 315, 415, 515), which is waterproof and vapor-permeable and surrounds the foot completely, - a vapor-permeable or perforated upper (16, 116, 216, 316, 416, 516), the outer bottom portion (17, 117, 217, 317, 417) of said top shoe part (13, 113, 213, 313, 413, 513), which is superimposed on the perforated area of said sole (12, 112, 212, 312, 412, 512), being constituted by a portion (15a, 115a, 215a, 315a, 415a, 515a) of said membrane (15, 115, 215, 315, 415, 515), a vapor-permeable or perforated protective element (22, 122, 222, 322, 422, 522) for said portion (15a, 115a, 215a, 315a, 415a, 515a) of the membrane (15, 115, 215, 315, 415, 515) being provided below said portion (15a, 115a, 215a, 315a, 415a, 515a) of the membrane (15, 115, 215, 315, 415, 515) and above the tread of said sole (12, 112, 212, 312, 412, 512), the material arranged below said portion (15a, 115a, 215a, 315a, 415a, 515a) of the membrane (15, 115, 215, 315, 415, 515) and in direct contact therewith being waterproof and/or not retaining liquids, a water sealing region (A, 1A, 2A, 3A, 4A, 5A) being provided between said portion (15a, 115a, 215a, 315a, 415a, 515a) of the membrane (15, 115, 215, 315, 415, 515) and said sole (12, 112, 212, 312, 412, 512), around the perforated area of said sole, and separating the flaps of said upper from the perforated area of said sole (12, 112, 212, 312, 412, 512). - a bottom shoe part (11, 111, 211, 311, 411, 511), which comprises a sole (12, 112, 212, 312, 412, 512) that is perforated through from the tread toward the foot resting region, - a top part (13, 113, 213, 313, 413, 513), which surrounds the foot completely and in turn comprises, from the inside outwardly: - a vapor-permeable or perforated lining (14, 114, 214, 314, 414,514), - a membrane (15, 115, 215, 315, 415, 515), which is waterproof and vapor-permeable and surrounds the foot completely, - a vapor-permeable or perforated upper (16, 116, 216, 316, 416, 516), the outer bottom portion (17, 117, 217, 317, 417) of said top shoe part (13, 113, 213, 313, 413, 513), which is superimposed on the perforated area of said sole (12, 112, 212, 312, 412, 512), being constituted by a portion (15a, 115a, 215a, 315a, 415a, 515a) of said membrane (15, 115, 215, 315, 415, 515), a vapor-permeable or perforated protective element (22, 122, 222, 322, 422, 522) for said portion (15a, 115a, 215a, 315a, 415a, 515a) of the membrane (15, 115, 215, 315, 415, 515) being provided below said portion (15a, 115a, 215a, 315a, 415a, 515a) of the membrane (15, 115, 215, 315, 415, 515) and above the tread of said sole (12, 112, 212, 312, 412, 512), the material arranged below said portion (15a, 115a, 215a, 315a, 415a, 515a) of the membrane (15, 115, 215, 315, 415, 515) and in direct contact therewith being waterproof and/or not retaining liquids, a water sealing region (A, 1A, 2A, 3A, 4A, 5A) being provided between said portion (15a, 115a, 215a, 315a, 415a, 515a) of the membrane (15, 115, 215, 315, 415, 515) and said sole (12, 112, 212, 312, 412, 512), around the perforated area of said sole, and separating the flaps of said upper from the perforated area of said sole (12, 112, 212, 312, 412, 512). - a vapor-permeable or perforated lining (14, 114, 214, 314, 414,514), - a membrane (15, 115, 215, 315, 415, 515), which is waterproof and vapor-permeable and surrounds the foot completely, - a vapor-permeable or perforated upper (16, 116, 216, 316, 416, 516), the outer bottom portion (17, 117, 217, 317, 417) of said top shoe part (13, 113, 213, 313, 413, 513), which is superimposed on the perforated area of said sole (12, 112, 212, 312, 412, 512), being constituted by a portion (15a, 115a, 215a, 315a, 415a, 515a) of said membrane (15, 115, 215, 315, 415, 515),