A liquid pharmaceutical composition comprising a polydimethylsiloxane-based solvent, and a polymer network comprising - structural units A derived from sterically hindered amines of the formula (a): wherein R 1 is -H, -OH, or C 1 -C 4 alkyl, R 2 to R 5 are independently selected from C 1 to C 4 alkyl, and X is -CH(X 1)- or -CH(X 1)CH 2 -, wherein X 1 is a free-radical polymerizable chemical group of the formula wherein R 6 is -H or -CH 3 and Z 1 is -O- or -NH-; - structural units B derived from alkyloxysilanes of the general formula (b): wherein R 7 is -O(X 2), wherein X 2 is C 1 to C 4 alkyl, R 8 and R 9 are independently selected from C 1 to C 4 alkyl or -O(X 3), wherein X 3 is C 1 to C 4 alkyl, and Y is a free-radical polymerizable chemical group of the formula wherein Z 2 is -(CH 2) m -, wherein m = 0 to 6; or of the formula wherein R 10 is -H or -CH 3 and Z 3 is -(CH 2) n -, wherein n = 1 to 6; - structural units C derived from alkylsiloxanes of the formula (c): wherein R 11 is -H or -CH 3, Z 4 is -O- or -NH-, R 12 is - (CH 2) o -, wherein o = 1 to 6, R 13 to R 15 are independently selected from C 1 to C 4 alkyl or -OSi(X 4) 3, wherein X 4 is C 1 to C 4 alkyl, wherein X 4 are the same or different, R 16 and R 17 are independently selected from C 1 to C 4 alkyl or -OSi(X 5) 3, and X 5 is C 1 to C 4 alkyl or -OSi(X 6) 3 wherein X 6 is C 1 to C 4 alkyl, wherein X 5 is the same or different; - and optionally structural units D derived from monomers selected from the group comprising (meth)acrylamide monomers, alkyl (meth)acrylates, alkyl (meth)acrylamides, alkyloxy terminated (polyoxyethylene) (meth)acrylates, alkyloxy terminated (polyoxyethylene) (meth)acrylamides, N,N- dialkylaminoalkyl (meth)acrylates, N, N -dialkylaminoalkyl (meth)acrylamides, N -vinyl-2-pyrrolidone; wherein the alkyls in these substituents are C 1 -C 14 alkyls, preferably C 1 -C 12 alkyls or Ci-Cs alkyls. - structural units A derived from sterically hindered amines of the formula (a): wherein R 1 is -H, -OH, or C 1 -C 4 alkyl, R 2 to R 5 are independently selected from C 1 to C 4 alkyl, and X is -CH(X 1)- or -CH(X 1)CH 2 -, wherein X 1 is a free-radical polymerizable chemical group of the formula wherein R 6 is -H or -CH 3 and Z 1 is -O- or -NH-; R 2 to R 5 are independently selected from C 1 to C 4 alkyl, and X is -CH(X 1)- or -CH(X 1)CH 2 -, wherein X 1 is a free-radical polymerizable chemical group of the formula wherein R 6 is -H or -CH 3 and Z 1 is -O- or -NH-; - structural units B derived from alkyloxysilanes of the general formula (b): wherein R 7 is -O(X 2), wherein X 2 is C 1 to C 4 alkyl, R 8 and R 9 are independently selected from C 1 to C 4 alkyl or -O(X 3), wherein X 3 is C 1 to C 4 alkyl, and Y is a free-radical polymerizable chemical group of the formula wherein Z 2 is -(CH 2) m -, wherein m = 0 to 6; or of the formula wherein R 10 is -H or -CH 3 and Z 3 is -(CH 2) n -, wherein n = 1 to 6; R 8 and R 9 are independently selected from C 1 to C 4 alkyl or -O(X 3), wherein X 3 is C 1 to C 4 alkyl, and Y is a free-radical polymerizable chemical group of the formula wherein Z 2 is -(CH 2) m -, wherein m = 0 to 6; or of the formula wherein R 10 is -H or -CH 3 and Z 3 is -(CH 2) n -, wherein n = 1 to 6; - structural units C derived from alkylsiloxanes of the formula (c): wherein R 11 is -H or -CH 3, Z 4 is -O- or -NH-, R 12 is - (CH 2) o -, wherein o = 1 to 6, R 13 to R 15 are independently selected from C 1 to C 4 alkyl or -OSi(X 4) 3, wherein X 4 is C 1 to C 4 alkyl, wherein X 4 are the same or different, R 16 and R 17 are independently selected from C 1 to C 4 alkyl or -OSi(X 5) 3, and X 5 is C 1 to C 4 alkyl or -OSi(X 6) 3 wherein X 6 is C 1 to C 4 alkyl, wherein X 5 is the same or different; Z 4 is -O- or -NH-, R 12 is - (CH 2) o -, wherein o = 1 to 6, R 13 to R 15 are independently selected from C 1 to C 4 alkyl or -OSi(X 4) 3, wherein X 4 is C 1 to C 4 alkyl, wherein X 4 are the same or different, R 16 and R 17 are independently selected from C 1 to C 4 alkyl or -OSi(X 5) 3, and X 5 is C 1 to C 4 alkyl or -OSi(X 6) 3 wherein X 6 is C 1 to C 4 alkyl, wherein X 5 is the same or different; - and optionally structural units D derived from monomers selected from the group comprising (meth)acrylamide monomers, alkyl (meth)acrylates, alkyl (meth)acrylamides, alkyloxy terminated (polyoxyethylene) (meth)acrylates, alkyloxy terminated (polyoxyethylene) (meth)acrylamides, N,N- dialkylaminoalkyl (meth)acrylates, N, N -dialkylaminoalkyl (meth)acrylamides, N -vinyl-2-pyrrolidone; wherein the alkyls in these substituents are C 1 -C 14 alkyls, preferably C 1 -C 12 alkyls or Ci-Cs alkyls.