A building structure provided with lateral walls comprising a thermoplastic polymer, comprising: - a plurality of vertical walls which are arranged on a plurality of levels, each wall comprising at least one first substantially continuous central panel made of a thermoplastic polymer and a pair of layers of cement plaster which are arranged on the opposite sides of the corresponding first central panel and form the opposite faces of the corresponding vertical wall; the vertical walls of the lowest level being fixed in a lower region to a reference plane and the vertical walls of each level being mutually connected for delimiting one or more closed perimeters; - at least one covering wall, which is fixed in an upper region to the vertical walls of each one of said levels in order to form one or more closed volumes and to mutually separate said levels, the covering wall of the highest level forming the roof of said building structure; - a metallic structure for connecting at least the vertical walls of each one of said levels, wherein said metallic structure comprises, for each one of said vertical walls, at least one pair of first metallic vertical elements, which are C-shaped and substantially without discontinuities, are arranged at the lateral ends of said vertical walls and form a receptacle for the corresponding first central panel; - characterized in that - the plaster of the pair of layers is a cement plaster, and - in that said metallic structure comprises, for each one of said vertical walls, two first wire meshes, which are mutually jointly associated, each of which is interposed between one side of the corresponding first central panel and the corresponding layers of plaster; the first wire meshes directed toward the incident faces of two of said vertical walls which are mutually connected being jointly associated with each other. - a plurality of vertical walls which are arranged on a plurality of levels, each wall comprising at least one first substantially continuous central panel made of a thermoplastic polymer and a pair of layers of cement plaster which are arranged on the opposite sides of the corresponding first central panel and form the opposite faces of the corresponding vertical wall; the vertical walls of the lowest level being fixed in a lower region to a reference plane and the vertical walls of each level being mutually connected for delimiting one or more closed perimeters; - at least one covering wall, which is fixed in an upper region to the vertical walls of each one of said levels in order to form one or more closed volumes and to mutually separate said levels, the covering wall of the highest level forming the roof of said building structure; - a metallic structure for connecting at least the vertical walls of each one of said levels, wherein said metallic structure comprises, for each one of said vertical walls, at least one pair of first metallic vertical elements, which are C-shaped and substantially without discontinuities, are arranged at the lateral ends of said vertical walls and form a receptacle for the corresponding first central panel; - characterized in that - the plaster of the pair of layers is a cement plaster, and - in that said metallic structure comprises, for each one of said vertical walls, two first wire meshes, which are mutually jointly associated, each of which is interposed between one side of the corresponding first central panel and the corresponding layers of plaster; the first wire meshes directed toward the incident faces of two of said vertical walls which are mutually connected being jointly associated with each other.