A system for providing instillation fluid to a deep abdominal wound, comprising: an instillation module (30, 288) defining a first surface and a second, abdominal contents-facing surface, the instillation module including a distribution hub (72, 304) configured to receive instillation fluid from an instillation fluid source; a negative pressure manifold including a first surface and a second, abdominal contents-facing surface; a connection structure (150, 210, 258) comprising a first surface; a second, abdominal contents-facing surface; and a flow path extending between the first surface of the connection structure (150, 210, 258) and the second surface of the connection structure (150, 210,258), the flow path including an inlet configured to be in fluid communication with an instillation fluid conduit engaged with an instillation fluid source and an outlet in fluid communication with the distribution hub (72, 304) of the instillation module (30, 288), the flow path defining an axis extending between the inlet and the outlet and configured to compress in a direction defined by the axis, wherein the second surface of the connection structure (150, 210, 258) is secured to the first surface of the instillation module (30, 288) to provide a fluid-tight connection between the flow path and the instillation module (30, 288); and a connection plate (42, 126) secured to the negative pressure manifold and including an instillation inlet connector having a first shape in fluid communication with the distribution hub (72, 304) via the flow path and a negative pressure inlet connector having a second shape different than the first shape, the negative pressure inlet connector in fluid communication with the negative pressure manifold. an instillation module (30, 288) defining a first surface and a second, abdominal contents-facing surface, the instillation module including a distribution hub (72, 304) configured to receive instillation fluid from an instillation fluid source; a negative pressure manifold including a first surface and a second, abdominal contents-facing surface; a connection structure (150, 210, 258) comprising a first surface; a second, abdominal contents-facing surface; and a flow path extending between the first surface of the connection structure (150, 210, 258) and the second surface of the connection structure (150, 210,258), the flow path including an inlet configured to be in fluid communication with an instillation fluid conduit engaged with an instillation fluid source and an outlet in fluid communication with the distribution hub (72, 304) of the instillation module (30, 288), the flow path defining an axis extending between the inlet and the outlet and configured to compress in a direction defined by the axis, wherein the second surface of the connection structure (150, 210, 258) is secured to the first surface of the instillation module (30, 288) to provide a fluid-tight connection between the flow path and the instillation module (30, 288); and a first surface; a second, abdominal contents-facing surface; and a flow path extending between the first surface of the connection structure (150, 210, 258) and the second surface of the connection structure (150, 210,258), the flow path including an inlet configured to be in fluid communication with an instillation fluid conduit engaged with an instillation fluid source and an outlet in fluid communication with the distribution hub (72, 304) of the instillation module (30, 288), the flow path defining an axis extending between the inlet and the outlet and configured to compress in a direction defined by the axis, wherein the second surface of the connection structure (150, 210, 258) is secured to the first surface of the instillation module (30, 288) to provide a fluid-tight connection between the flow path and the instillation module (30, 288); and a connection plate (42, 126) secured to the negative pressure manifold and including an instillation inlet connector having a first shape in fluid communication with the distribution hub (72, 304) via the flow path and a negative pressure inlet connector having a second shape different than the first shape, the negative pressure inlet connector in fluid communication with the negative pressure manifold.