mhurhangee/ep-ind-claims huggingface dataset:
An in vivo positionable filtration device (100, 300) for filtering one or more therapeutic agents in blood flowing in a blood vessel, the filtration device comprising: an elongated member (101, 307); and a conical filtering component coupled to the elongated member, the filtering component comprising: a frame structure (103, 303, 403, 503) coupled to a distal end of the elongated member, wherein the frame structure has a circular cross shape to conform to circular cross shape of the blood vessel and is tapered from distal end towards proximal end to facilitate blood flow through the filtering component; a single membrane or multiple membranes (304a, 304b, 404a, 404b) coupled to the frame structure; and filtration material (105, 305, 405) disposed on the single membrane or between the multiple membranes, wherein the elongated member, the frame structure, and the filtering component are dimensioned for positioning within a blood vessel of a human or non-human animal; wherein the filtration material (105, 305, 405) filters a therapeutic agent from blood, and wherein the filtering component is conical shaped when the frame structure is expanded. an elongated member (101, 307); and a conical filtering component coupled to the elongated member, the filtering component comprising: a frame structure (103, 303, 403, 503) coupled to a distal end of the elongated member, wherein the frame structure has a circular cross shape to conform to circular cross shape of the blood vessel and is tapered from distal end towards proximal end to facilitate blood flow through the filtering component; a single membrane or multiple membranes (304a, 304b, 404a, 404b) coupled to the frame structure; and filtration material (105, 305, 405) disposed on the single membrane or between the multiple membranes, wherein the elongated member, the frame structure, and the filtering component are dimensioned for positioning within a blood vessel of a human or non-human animal; a frame structure (103, 303, 403, 503) coupled to a distal end of the elongated member, wherein the frame structure has a circular cross shape to conform to circular cross shape of the blood vessel and is tapered from distal end towards proximal end to facilitate blood flow through the filtering component; a single membrane or multiple membranes (304a, 304b, 404a, 404b) coupled to the frame structure; and filtration material (105, 305, 405) disposed on the single membrane or between the multiple membranes, wherein the elongated member, the frame structure, and the filtering component are dimensioned for positioning within a blood vessel of a human or non-human animal; wherein the filtration material (105, 305, 405) filters a therapeutic agent from blood, and wherein the filtering component is conical shaped when the frame structure is expanded.
A method performed by a network node for handling a service request for an edge connectivity service from an application server in a communication network, wherein the application server comprises an application providing an end-user service to a user equipment, wherein the edge connectivity service is a connectivity between the application and the user equipment accessing the end-user service, the method comprising: - configuring the application with the edge connectivity service for the user equipment, wherein configuring comprises: - setting up configuration for the edge connectivity service by negotiating with the application server for determining the configuration of the edge connectivity service and by registering the edge connectivity service with the configuration for the application; - receiving the service request for the edge connectivity service from the application server, wherein the service request comprises an indication of the user equipment; and - setting up a configuration of one or more radio network nodes of a radio access network for providing the edge connectivity service to the user equipment. - configuring the application with the edge connectivity service for the user equipment, wherein configuring comprises: - setting up configuration for the edge connectivity service by negotiating with the application server for determining the configuration of the edge connectivity service and by registering the edge connectivity service with the configuration for the application; - receiving the service request for the edge connectivity service from the application server, wherein the service request comprises an indication of the user equipment; and - setting up a configuration of one or more radio network nodes of a radio access network for providing the edge connectivity service to the user equipment. - setting up configuration for the edge connectivity service by negotiating with the application server for determining the configuration of the edge connectivity service and by registering the edge connectivity service with the configuration for the application; - receiving the service request for the edge connectivity service from the application server, wherein the service request comprises an indication of the user equipment; and - setting up a configuration of one or more radio network nodes of a radio access network for providing the edge connectivity service to the user equipment.
Mould for vulcanizing and moulding a tyre, this tyre comprising a tread delimited by two sidewalls, the mould comprising a ring intended for moulding the tread of the tyre and two shells having tyre-moulding surface features for moulding the sidewalls, at least one of the shells intended for moulding one of the sidewalls having a removable shell part, extending circumferentially on the side of the sidewall of the tyre to be moulded, said moulding surface features being incorporated into said removable shell part, characterized in the the thickness of the removable shell part is between 0.25 and 4.00 mm, and preferably between 2.50 and 3.00 mm and in that the removable shell part is formed from a plurality of sections (6a-6h) that are positioned one after another against the bearing surface of the shell.
A method of making a population of immune effector cells (e.g., T cells, or NK cells) that is depleted of CD25+ T regulatory cells and CD25-expressing chronic lymphocytic leukemia cells and which can be engineered to express a CD19 CAR, the method comprising: (i) providing a population of immune effector cells (e.g., T cells) from a subject having CLL, and (ii) contacting the population of immune effector cells with an anti-CD25 antibody or a CD25 binding ligand to remove CD25+ T regulatory cells and CD25-expressing CLL cells, thereby providing a population of immune effector cells that contains less than 50%, 40%, 30%, 25%, 20%, 15%, 10%, 5%, 4%, 3%, 2%, or 1% of CD25+ cells and less than 50%, 40%, 30%, 25%, 20%, 15%, 10%, 5%, 4%, 3%, 2%, or 1% of CD25+ CLL cells. (i) providing a population of immune effector cells (e.g., T cells) from a subject having CLL, and (ii) contacting the population of immune effector cells with an anti-CD25 antibody or a CD25 binding ligand to remove CD25+ T regulatory cells and CD25-expressing CLL cells,
A directed-energy irradiating apparatus comprising: a free electron laser apparatus configured to accelerate free electrons by using microwave, and irradiate a FEL beam generated from the accelerated free electrons to a target; characterised in that it further comprises; a high power microwave apparatus configured to irradiate an HPM beam generated based on the microwave, to the target; and a control unit (40;29) configured to select at least one of the FEL beam and the HPM beam as directed-energy to be irradiated based on external environmental data. a free electron laser apparatus configured to accelerate free electrons by using microwave, and irradiate a FEL beam generated from the accelerated free electrons to a target; characterised in that it further comprises; a high power microwave apparatus configured to irradiate an HPM beam generated based on the microwave, to the target; and a control unit (40;29) configured to select at least one of the FEL beam and the HPM beam as directed-energy to be irradiated based on external environmental data.
A method for providing location-based configuration profile toggling, the method being executed by an apparatus (100, 210) comprising at least one memory storage and at least one processor coupled to said memory storage, the method comprising: identifying at least one configuration profile associated with at least one user device, said user device being a mobile device; and characterized by determining whether said user device is authorized to enable said configuration profile on said user device based at least in part on a current location associated with said user device wherein said determining comprises: determining whether said current location associated with said user device complies with at least one compliance rule specifying at least one authorized location where said user device is authorized to enable said configuration profile on said user device and wherein said at least one compliance rule requires that said user device is located within a proximity of a second device and that both said user device and said second device are within the at least one authorized location, said second device being a mobile device; and, enabling said configuration profile on said user device in response to a determination that said user device is authorized to enable said configuration profile on said user device based at least in part on said current location associated with said user device being in the proximity of the second device. identifying at least one configuration profile associated with at least one user device, said user device being a mobile device; and characterized by determining whether said user device is authorized to enable said configuration profile on said user device based at least in part on a current location associated with said user device wherein said determining comprises: determining whether said current location associated with said user device complies with at least one compliance rule specifying at least one authorized location where said user device is authorized to enable said configuration profile on said user device and wherein said at least one compliance rule requires that said user device is located within a proximity of a second device and that both said user device and said second device are within the at least one authorized location, said second device being a mobile device; and, determining whether said current location associated with said user device complies with at least one compliance rule specifying at least one authorized location where said user device is authorized to enable said configuration profile on said user device and wherein said at least one compliance rule requires that said user device is located within a proximity of a second device and that both said user device and said second device are within the at least one authorized location, said second device being a mobile device; and, enabling said configuration profile on said user device in response to a determination that said user device is authorized to enable said configuration profile on said user device based at least in part on said current location associated with said user device being in the proximity of the second device.
A rod, the length of which is variable, for adjusting the compression ratio of an engine, said rod having a nominal length and being likely to be subjected to tensile and compression forces along its longitudinal axis, the rod comprising: - a cylinder rigidly connected to a first end (El) of the rod; - a piston movable in the cylinder, rigidly connected to the second end of the rod, and defining in the cylinder a first so-called "high pressure" hydraulic chamber capable of transmitting the compression forces and a second so-called "low pressure" hydraulic chamber capable of transmitting the tensile forces; - at least one pipe (6; 6a, 6b) calibrated to enable the hydraulic fluid to flow between the low pressure chamber and the high pressure chamber; - mechanical return means tending to bring the rod back to its nominal length; and characterized in that the low pressure hydraulic chamber and the high pressure hydraulic chamber have equal cross-sections. - a cylinder rigidly connected to a first end (El) of the rod; - a piston movable in the cylinder, rigidly connected to the second end of the rod, and defining in the cylinder a first so-called "high pressure" hydraulic chamber capable of transmitting the compression forces and a second so-called "low pressure" hydraulic chamber capable of transmitting the tensile forces; - at least one pipe (6; 6a, 6b) calibrated to enable the hydraulic fluid to flow between the low pressure chamber and the high pressure chamber; - mechanical return means tending to bring the rod back to its nominal length;
A composition comprising at least two antibodies binding specifically a DR5 receptor, wherein the two antibodies comprise at least two immunoglobulin binding domains comprising: - a first binding domain comprising a pair of VH and VL chains, wherein the VH chain contains a CDR1 of sequence SEQ ID NO: 32, a CDR2 of sequence SEQ ID NO: 14, a CDR3 of sequence SEQ ID NO: 24; and the VL chain contains a CDR1 of sequence SEQ ID NO: 16, a CDR2 of sequence FAS, a CDR3 of sequence SEQ ID NO: 17, and - a second binding domain comprising a pair of VH and VL chains, wherein the VH chain contains a CDR1 of sequence SEQ ID NO: 33, a CDR2 of sequence SEQ ID NO: 14, a CDR3 of sequence SEQ ID NO: 29; and the VL chain contains a CDR1 of sequence SEQ ID NO: 20, a CDR2 of sequence RTS, a CDR3 of sequence SEQ ID NO: 21. - a first binding domain comprising a pair of VH and VL chains, wherein the VH chain contains a CDR1 of sequence SEQ ID NO: 32, a CDR2 of sequence SEQ ID NO: 14, a CDR3 of sequence SEQ ID NO: 24; and the VL chain contains a CDR1 of sequence SEQ ID NO: 16, a CDR2 of sequence FAS, a CDR3 of sequence SEQ ID NO: 17, and - a second binding domain comprising a pair of VH and VL chains, wherein the VH chain contains a CDR1 of sequence SEQ ID NO: 33, a CDR2 of sequence SEQ ID NO: 14, a CDR3 of sequence SEQ ID NO: 29; and the VL chain contains a CDR1 of sequence SEQ ID NO: 20, a CDR2 of sequence RTS, a CDR3 of sequence SEQ ID NO: 21.
Fuel injector, in particular common rail injector, having an injector housing in which a high-pressure space is formed, which is able to be supplied with pressurized fuel via a supply bore arranged in the injector housing, having at least one injection opening, connected at least indirectly to the high-pressure space and formed in the injector housing, for injecting fuel into the combustion chamber of an internal combustion engine, having an injection valve element that opens up or closes off the at least one injection opening, and having a measuring device for at least indirectly detecting the pressure in the high-pressure space or the supply bore, wherein the measuring device is configured to detect an elastic deformation of a deformation region that is arranged so as to be operatively connected at least indirectly to the supply bore or the high-pressure space, and wherein the measuring device has a sensor element which is connected to the surface of the deformation region via an adhesive bond, characterized in that at least the region of the adhesive bond between the deformation region and the sensor element is surrounded by a housing element which seals off at least the region of the adhesive bond from the external environment in a media-tight manner, wherein the housing element is filled with an inert gas in the region between the housing element and the adhesive bond.
A medical implant for use in a left atrial appendage, comprising: a central elongated member having an anchor at a distal end thereof; a plurality of elongated metallic legs joined together at a joint, the joint being coupled to the central elongated member; a distal stop disposed on the central elongated member proximal of the anchor; and a proximal stop disposed on the central elongate member proximal of the distal stop, wherein the joint is disposed proximally of the distal stop and is disposed between the proximal stop and the distal stop and the joint is axially slidable along the central elongated member between the proximal stop and the distal stop, wherein the plurality of elongated metallic legs is configured to expand radially outward from a delivery configuration to a deployed configuration, wherein each of the plurality of elongated metallic legs extends distally from the joint to a distal tip. a central elongated member having an anchor at a distal end thereof; a plurality of elongated metallic legs joined together at a joint, the joint being coupled to the central elongated member; a distal stop disposed on the central elongated member proximal of the anchor; and a proximal stop disposed on the central elongate member proximal of the distal stop, wherein the joint is disposed proximally of the distal stop and is disposed between the proximal stop and the distal stop and the joint is axially slidable along the central elongated member between the proximal stop and the distal stop, wherein the plurality of elongated metallic legs is configured to expand radially outward from a delivery configuration to a deployed configuration, wherein each of the plurality of elongated metallic legs extends distally from the joint to a distal tip.
An apparatus, comprising: a protective headgear; a sensor element integrated within the protective headgear, wherein the sensor element is attached or rigidly bonded on an inner surface of the protective headgear; and characterised by: an actuator element integrated within the protective headgear; a processor element electronically coupled to the actuator element and the sensor element, wherein the processor element is configured to: cause the actuator element to generate a first ultrasonic wave, wherein the first ultrasonic wave is propagated in the protective headgear; and receive a first output from the sensor element in response to the first ultrasonic wave. a protective headgear; a sensor element integrated within the protective headgear, wherein the sensor element is attached or rigidly bonded on an inner surface of the protective headgear; and characterised by: an actuator element integrated within the protective headgear; a processor element electronically coupled to the actuator element and the sensor element, wherein the processor element is configured to: cause the actuator element to generate a first ultrasonic wave, wherein the first ultrasonic wave is propagated in the protective headgear; and receive a first output from the sensor element in response to the first ultrasonic wave. an actuator element integrated within the protective headgear; a processor element electronically coupled to the actuator element and the sensor element, wherein the processor element is configured to: cause the actuator element to generate a first ultrasonic wave, wherein the first ultrasonic wave is propagated in the protective headgear; and receive a first output from the sensor element in response to the first ultrasonic wave. cause the actuator element to generate a first ultrasonic wave, wherein the first ultrasonic wave is propagated in the protective headgear; and receive a first output from the sensor element in response to the first ultrasonic wave.
A composition for use as component of a multicomponent resin-modified glass ionomer cement, the composition comprising - one or more radically polymerizable organic monomers and also, as constituent of a polymerization initiator system for it - one or more compounds selected from the group consisting of the isomers of ascorbic acid, the salts of the isomers of ascorbic acid, the esters of the isomers of ascorbic acid and the ethers of the isomers of ascorbic acid and - one or more compounds selected from the group consisting of sulfinic acids, salts of sulfinic acids and salts of organoboron compounds additionally comprising a basic glass composition as crosslinking agent for polymers containing carboxylic acid groups selected from the group consisting of homo- and copolymers of an α,β-unsaturated carboxylic acid. - one or more radically polymerizable organic monomers and also, as constituent of a polymerization initiator system for it - one or more compounds selected from the group consisting of the isomers of ascorbic acid, the salts of the isomers of ascorbic acid, the esters of the isomers of ascorbic acid and the ethers of the isomers of ascorbic acid and - one or more compounds selected from the group consisting of sulfinic acids, salts of sulfinic acids and salts of organoboron compounds
A method of wireless communication, comprising: transmitting a first peer discovery signal with a first periodicity in a first set of peer discovery resources; determining an energy on a first peer discovery resource of a second set of peer discovery resources, wherein the second set of peer discovery resources are distinct from the first set of peer discovery resources; refraining from transmitting a second peer discovery signal in the second set of peer discovery resources when the energy on the first peer discovery resource is greater than a threshold; and transmitting the second peer discovery signal on a second peer discovery resource in the second set of peer discovery resources with a second periodicity less than the first periodicity when the energy is less than the threshold. transmitting a first peer discovery signal with a first periodicity in a first set of peer discovery resources; determining an energy on a first peer discovery resource of a second set of peer discovery resources, wherein the second set of peer discovery resources are distinct from the first set of peer discovery resources; refraining from transmitting a second peer discovery signal in the second set of peer discovery resources when the energy on the first peer discovery resource is greater than a threshold; and transmitting the second peer discovery signal on a second peer discovery resource in the second set of peer discovery resources with a second periodicity less than the first periodicity when the energy is less than the threshold.