A compound having one of the formulae: or wherein: each of P 1 and P 2 individually is a protecting group or a hydrogen atom; - - - - - - represents a double bond; Z is -C OR d, -C NR c R c, -C H, -C NR c R c, -C H, -C OR d, -C NR c R c, or -CN; each R a, is independently selected from hydrogen, (C1-C6) alkyl, (C3-C8) cycloalkyl, cyclohexyl, (C4-C11) cycloalkylalkyl, (C5-C10) aryl, phenyl, (C6-C16) arylalkyl, benzyl, 2-6 membered heteroalkyl, 3-8 membered cycloheteroalkyl, morpholinyl, piperazinyl, homopiperazinyl, piperidinyl, 4-11 membered cycloheteroalkylalkyl, 5-10 membered heteroaryl or 6-16 membered heteroarylalkyl; each R c, is independently a protecting group or R a, or, alternatively, each R c is taken together with the nitrogen atom to which it is bonded to form a 5 to 8-membered cycloheteroalkyl or heteroaryl which may optionally include one or more of the same or different additional heteroatoms and which may optionally be substituted with one or more of the same or different R a or suitable R b groups; each R b is independently selected from =O, -OR d, (C1-C3) haloalkyloxy, -OCF 3, =S, -SR d, =NR d, =NOR d, -NR c R c, halogen, -CF 3, -CN, -NC, -OCN, -SCN, -NO, -NO 2, =N 2, -N 3, -S R d, -S 2 R d, -S 2 OR d, -S NR c R c, -S 2 NR c R c, -OS R d, -OS 2 R d, -OS 2 OR d, -OS 2 NR c R c, -C R d, -C OR d, -C NR c R c, -C NR c R c, -C(NR a)NR c R c, -C R a, -C NR c R c, -OC R d, -OC OR d, -OC NR c R c, -OC NR c R c, -OC(NR a)NR c R c, -[NHC] n R d, -[NR a C] n R d, -[NHC] n OR d, -[NR a C] n OR d, -[NHC] n NR c R c, -[NR a C] n NR c R c, -[NHC] n NR c R c or -[NR a C(NR a)] n NR c R c; each n, independently is an integer from 0 to 3; and each R d, independently is a protecting group or R a; wherein "alkyl" by itself or as part of another substituent refers to a saturated or unsaturated branched, straight-chain or cyclic monovalent hydrocarbon radical having the stated number of carbon atoms that is derived by the removal of one hydrogen atom from a single carbon atom of a parent alkane, alkene or alkyne; provided that: (i) the compound is purified; and/or (ii) when Z is -C OR d, then R d for Z is not a hydrogen when P 1 and P 2 are both hydrogen atoms. each of P 1 and P 2 individually is a protecting group or a hydrogen atom; - - - - - - represents a double bond; Z is -C OR d, -C NR c R c, -C H, -C NR c R c, -C H, -C OR d, -C NR c R c, or -CN; each R a, is independently selected from hydrogen, (C1-C6) alkyl, (C3-C8) cycloalkyl, cyclohexyl, (C4-C11) cycloalkylalkyl, (C5-C10) aryl, phenyl, (C6-C16) arylalkyl, benzyl, 2-6 membered heteroalkyl, 3-8 membered cycloheteroalkyl, morpholinyl, piperazinyl, homopiperazinyl, piperidinyl, 4-11 membered cycloheteroalkylalkyl, 5-10 membered heteroaryl or 6-16 membered heteroarylalkyl; each R c, is independently a protecting group or R a, or, alternatively, each R c is taken together with the nitrogen atom to which it is bonded to form a 5 to 8-membered cycloheteroalkyl or heteroaryl which may optionally include one or more of the same or different additional heteroatoms and which may optionally be substituted with one or more of the same or different R a or suitable R b groups; each R b is independently selected from =O, -OR d, (C1-C3) haloalkyloxy, -OCF 3, =S, -SR d, =NR d, =NOR d, -NR c R c, halogen, -CF 3, -CN, -NC, -OCN, -SCN, -NO, -NO 2, =N 2, -N 3, -S R d, -S 2 R d, -S 2 OR d, -S NR c R c, -S 2 NR c R c, -OS R d, -OS 2 R d, -OS 2 OR d, -OS 2 NR c R c, -C R d, -C OR d, -C NR c R c, -C NR c R c, -C(NR a)NR c R c, -C R a, -C NR c R c, -OC R d, -OC OR d, -OC NR c R c, -OC NR c R c, -OC(NR a)NR c R c, -[NHC] n R d, -[NR a C] n R d, -[NHC] n OR d, -[NR a C] n OR d, -[NHC] n NR c R c, -[NR a C] n NR c R c, -[NHC] n NR c R c or -[NR a C(NR a)] n NR c R c; each n, independently is an integer from 0 to 3; and each R d, independently is a protecting group or R a; wherein "alkyl" by itself or as part of another substituent refers to a saturated or unsaturated branched, straight-chain or cyclic monovalent hydrocarbon radical having the stated number of carbon atoms that is derived by the removal of one hydrogen atom from a single carbon atom of a parent alkane, alkene or alkyne; provided that: (i) the compound is purified; and/or (ii) when Z is -C OR d, then R d for Z is not a hydrogen when P 1 and P 2 are both hydrogen atoms. (i) the compound is purified; and/or (ii) when Z is -C OR d, then R d for Z is not a hydrogen when P 1 and P 2 are both hydrogen atoms.