mhurhangee/ep-ind-claims huggingface dataset:
A mass spectrometer comprising: a first vacuum chamber; an atmospheric pressure ion source for generating first ions, wherein first ions generated by said atmospheric pressure ion source are transmitted, in use, into said first vacuum chamber via a sampling cone or first aperture; a device for generating second ions; and one or more dispensing devices (16,19) for dispensing one or more reagents in proximity to said device; wherein said one or more reagents comprise one or more lock mass or calibration reagents for mass calibrating the mass spectrometer; characterised in that: said second ions generated by said device are generated within said first vacuum chamber; said ionised reagents and said first ions are onwardly transmitted from said first vacuum chamber into a second vacuum chamber through the same extraction cone; said device is a glow discharge device located within the first vacuum chamber; and the glow discharge device comprises a discharge pin and said one or more reagents are ionised, in use, by a glow discharge caused or generated by the discharge pin of the glow discharge device. a first vacuum chamber; an atmospheric pressure ion source for generating first ions, wherein first ions generated by said atmospheric pressure ion source are transmitted, in use, into said first vacuum chamber via a sampling cone or first aperture; a device for generating second ions; and one or more dispensing devices (16,19) for dispensing one or more reagents in proximity to said device; wherein said one or more reagents comprise one or more lock mass or calibration reagents for mass calibrating the mass spectrometer; characterised in that: said second ions generated by said device are generated within said first vacuum chamber; said ionised reagents and said first ions are onwardly transmitted from said first vacuum chamber into a second vacuum chamber through the same extraction cone; said device is a glow discharge device located within the first vacuum chamber; and the glow discharge device comprises a discharge pin and said one or more reagents are ionised, in use, by a glow discharge caused or generated by the discharge pin of the glow discharge device. said second ions generated by said device are generated within said first vacuum chamber; said ionised reagents and said first ions are onwardly transmitted from said first vacuum chamber into a second vacuum chamber through the same extraction cone; said device is a glow discharge device located within the first vacuum chamber; and the glow discharge device comprises a discharge pin and said one or more reagents are ionised, in use, by a glow discharge caused or generated by the discharge pin of the glow discharge device.
A surgical bending instrument for bending surgical staples, comprising: a body supporting a distal force applicator and a proximal handle fixedly coupled to a proximal end of a shaft; a first grip and a second grip of the distal force applicator configured to retain the surgical staple, wherein the first and second grips are configured to engage the surgical staple on opposite sides; and a driver of the distal force applicator configured to be able to contact a crown of the surgical staple in order to exert a distally-directed force so as to bend the surgical staple, characterised in that the shaft is threadably engaged within a longitudinally extending hole within the body, and a distal extension of the shaft comprises the driver. a body supporting a distal force applicator and a proximal handle fixedly coupled to a proximal end of a shaft; a first grip and a second grip of the distal force applicator configured to retain the surgical staple, wherein the first and second grips are configured to engage the surgical staple on opposite sides; and a driver of the distal force applicator configured to be able to contact a crown of the surgical staple in order to exert a distally-directed force so as to bend the surgical staple, characterised in that the shaft is threadably engaged within a longitudinally extending hole within the body, and a distal extension of the shaft comprises the driver.
An apparatus (20; 44) for placement on or in a body of water for hyperspectral imaging of material in the water, comprising an artificial light source, means for adjusting the spectrum of light emitted by the artificial light source, and a hyperspectral imager which are arranged so that in use light from said artificial light source exits the apparatus beneath the surface of the water and is reflected by said material before re-entering the apparatus beneath the surface of the water and entering said hyperspectral imager, wherein said hyperspectral imager is adapted to produce hyperspectral image data having at least two spatial dimensions, wherein the apparatus comprises an optical sensor and means for estimating a spectral attenuation coefficient of the ambient water using an output from the optical sensor, and wherein the apparatus is arranged to use such estimations of a spectral attenuation coefficient to tune the spectral output of the artificial light source so that a predetermined light spectrum arrives at said material or to compensate for the attenuation of reflected or emitted light returning to the apparatus.
Combing machine having multiple combing stations (K1-K8), wherein the slivers formed at the individual combing stations are fed via guide elements (T, 3) to a drafting unit, and the fiber fleece which is discharged from the drafting unit is combined via a fleece combiner (4, 14, 44) to form a sliver which is discharged onto a driven transport means, which transfers the sliver to a delivery point at which the sliver is deflected and discharged vertically downwardly to a sliver lay, characterized in that a pair of calender rollers, connected to a drive, is provided between the fleece combiner (4, 14, 44) and the transport means, wherein lateral guides (S1, S2) for the sliver which is guided through the nip point are provided in the area of the nip point of the pair of calender rollers.
Exterior aircraft light, which is one of a navigation light, an anti-collision light, a landing light, a runway turnoff light, a taxi light, and a logo light, comprising: a mounting board, having an upper side, a lower side and a plurality of side faces, and at least one LED, arranged on the upper side of the mounting board, characterised by a mounting board enclosure and lens structure, wherein the mounting board enclosure and lens structure comprises a lens arranged over the at least one LED for shaping an output light intensity distribution of the exterior aircraft light and a covering layer (84, 86, 88) arranged on the upper side, the lower side and the plurality of side faces of the mounting board, wherein the mounting board enclosure and lens structure is an integral silicone structure. a mounting board, having an upper side, a lower side and a plurality of side faces, and at least one LED, arranged on the upper side of the mounting board, characterised by a mounting board enclosure and lens structure, wherein the mounting board enclosure and lens structure comprises a lens arranged over the at least one LED for shaping an output light intensity distribution of the exterior aircraft light and a covering layer (84, 86, 88) arranged on the upper side, the lower side and the plurality of side faces of the mounting board, wherein the mounting board enclosure and lens structure is an integral silicone structure.
Transverse link having a main body, which has at least one first fixing region for pivotal attachment to a vehicle frame element and at least one further fixing region for pivotal attachment to a hub carrier, the main body having at least one wheel limb with a base, characterized by a transitional region with a curved profile, which is arranged between the wheel limb and the further fixing region, which transitional region has two webs (22, 23), the first web which is adjoined integrally by the second web leading out of the plane of the base and the second web which adjoins it leading back again in the direction of the plane of the base in the opposite direction to the said first web, and thus forms a deformation zone acting in the longitudinal direction of the wheel limb.
A replaceable shaving assembly comprising: a blade unit; an interface element configured to removeably connect the blade unit to a handle, on which the blade unit is pivotably mounted, the interface element including an elastomeric return element configured to provide a return force between the blade unit and the handle; wherein the angle of the blade unit with respect to the handle is 15 degrees at rest, and the angle of the blade unit with respect to the handle ranges from 15° to 105° during shaving; and comprising one or more support features located on the back surface of the blade unit that act as a stop for a distal end of the return element; wherein the return element is configured to bias the blade unit towards a rest position with respect to a pivot axis that is generally parallel to a long axis of the blade unit. a blade unit; an interface element configured to removeably connect the blade unit to a handle, on which the blade unit is pivotably mounted, the interface element including an elastomeric return element configured to provide a return force between the blade unit and the handle; wherein the angle of the blade unit with respect to the handle is 15 degrees at rest, and the angle of the blade unit with respect to the handle ranges from 15° to 105° during shaving; and comprising one or more support features located on the back surface of the blade unit that act as a stop for a distal end of the return element; wherein the return element is configured to bias the blade unit towards a rest position with respect to a pivot axis that is generally parallel to a long axis of the blade unit.
Natalizumab for use in a method of treating an inflammatory or autoimmune disease, wherein said method comprises: (a) administering a first dose of natalizumab for a first dosage period; (b) monitoring the amount of bivalent natalizumab in the patient's plasma or serum during the first dosage period; (c) determining a second dose of natalizumab based on the level of bivalent natalizumab observed; and (d) administering a second dose of natalizumab for a second dosage period; wherein if the monitoring shows that the amount of bivalent natalizumab in the patient's plasma or serum remains above a predetermined level during the first dosage period, then the second dose of natalizumab administered over the second dosage period is designed to achieve a reduction of the natalizumab level during the second dosage period to below the predetermined level during at least a portion of the second dosage period; wherein the second dose improves the safety and/or efficacy of the treatment during the second dosage period; and wherein the predetermined level of bivalent natalizumab in the patient's plasma or serum during the first dosage period is selected from 0.1 μg/mL, 0.5 μg/mL, and 1 μg/mL. (a) administering a first dose of natalizumab for a first dosage period; (b) monitoring the amount of bivalent natalizumab in the patient's plasma or serum during the first dosage period; (c) determining a second dose of natalizumab based on the level of bivalent natalizumab observed; and (d) administering a second dose of natalizumab for a second dosage period;
Isolated nucleic acid molecule comprising (a) a nucleotide sequence having the sequence of SEQ ID NO: 103 or a precursor of SEQ ID NO: 103 having the sequenceGAGUGCAUUCCGUAUGGAAGACUAGUGAUUUUGUUGUUUGGUCUUUGGUAAUAACAAUAAAUCCCUUGUCUUCUUACGGCGUGCAUUU, and/or (b) a nucleotide sequence which is the complement of (a), and/or (c) a nucleotide sequence comprising an miRNA or miRNA precursor, which has an identity of at least 80% to the sequence of (a) or (b), wherein the identity is determined as l = n: L, wherein I is the identity in percent, n is the number of identical nucleotides between a given sequence and a comparative sequence having the sequence of SEQ ID NO: 103 or a precursor thereof having the sequence GAGUGCAUUCCGUAUGGAAGACUAGUGAUUUUGUUGUUUGG UCUUUGGUAAUAACAAUAAAUCCCUUGUCUUCUUACGGCGU GCAUUU, or a complement of SEQ ID NO: 103 or said precursor, and L is the length of the comparative sequence, wherein said isolated nucleic acid comprising (a), (b) or (c) has a length of 18-100 nucleotides. (a) a nucleotide sequence having the sequence of SEQ ID NO: 103 or a precursor of SEQ ID NO: 103 having the sequenceGAGUGCAUUCCGUAUGGAAGACUAGUGAUUUUGUUGUUUGGUCUUUGGUAAUAACAAUAAAUCCCUUGUCUUCUUACGGCGUGCAUUU, and/or (b) a nucleotide sequence which is the complement of (a), and/or (c) a nucleotide sequence comprising an miRNA or miRNA precursor, which has an identity of at least 80% to the sequence of (a) or (b), wherein the identity is determined as l = n: L, wherein I is the identity in percent, n is the number of identical nucleotides between a given sequence and a comparative sequence having the sequence of SEQ ID NO: 103 or a precursor thereof having the sequence GAGUGCAUUCCGUAUGGAAGACUAGUGAUUUUGUUGUUUGG UCUUUGGUAAUAACAAUAAAUCCCUUGUCUUCUUACGGCGU GCAUUU, or a complement of SEQ ID NO: 103 or said precursor, and L is the length of the comparative sequence,
A composition, comprising a collagen material for the use in reducing the risk for developing post-traumatic arthritis in a joint when administered to the joint of a subject, wherein the collagen material comprises blood.
Assembly of a body in white of a motor vehicle and a hatch mounted on the body so as to be movable between an open position and a closed position, comprising means for assisting the opening of the hatch attached to the hatch by a first attachment means and attached to the body by a second attachment means, and comprising sealing means used to define a dry area between the body and the hatch, said hatch comprising at least one lateral upright, connecting an upper part and a lower part of the hatch, and to which a window can be attached, characterised in that the upright forms an H-shaped profile with open cross-section comprising at least one opening facing the body in white and contained in said dry area, intended to house the assistance means, and in that the assistance means is contained in said dry area.
A system (100, 200) for pacing a heart, comprising: an electrostimulation circuit configured to generate a His-bundle pacing pulse for delivery at or near a His bundle of the heart; a sensing circuit configured to sense, in response to the delivery of the HBP pulse, a near-field para-Hisian myocardial activity representative of excitation of a para-Hisian myocardial tissue, and a far-field cardiac activity representative of excitation of the His bundle and a ventricle; and a control circuit coupled to the sensing circuit and configured to classify a tissue response to the delivery of the HBP pulse into one of a plurality of capture types based on the sensed near-field para-Hisian myocardial activity and the sensed far-field cardiac activity. an electrostimulation circuit configured to generate a His-bundle pacing pulse for delivery at or near a His bundle of the heart; a sensing circuit configured to sense, in response to the delivery of the HBP pulse, a near-field para-Hisian myocardial activity representative of excitation of a para-Hisian myocardial tissue, and a far-field cardiac activity representative of excitation of the His bundle and a ventricle; and a control circuit coupled to the sensing circuit and configured to classify a tissue response to the delivery of the HBP pulse into one of a plurality of capture types based on the sensed near-field para-Hisian myocardial activity and the sensed far-field cardiac activity.
A method for producing a polymer, comprising: polymerizing a ring-opening polymerizable monomer in a compressive fluid with a metal-free organic catalyst to produce a polymer. polymerizing a ring-opening polymerizable monomer in a compressive fluid with a metal-free organic catalyst to produce a polymer.
A flow cell battery, comprising: at least one anode compartment; at least one cathode compartment; a separator membrane disposed between each said anode compartment and cathode compartment; each said anode compartment and said cathode compartment comprising: a flow channel; and a bipolar plate, fluid electrolyte and a carbon nanomaterial, characterized in that the carbon nanomaterial is attached directly to a surface of the bipolar plate, that the fluid electrolyte flows through and about said carbon nanomaterial, and that the carbon nanomaterial comprises cylindrically-shaped fullerenes. at least one anode compartment; at least one cathode compartment; a separator membrane disposed between each said anode compartment and cathode compartment; each said anode compartment and said cathode compartment comprising: a flow channel; and a bipolar plate, fluid electrolyte and a carbon nanomaterial, a flow channel; and a bipolar plate, fluid electrolyte and a carbon nanomaterial,
A process for preparing glycerol carbonate comprising the steps of: (i) contacting and partially reacting a glycerol reactant stream with: a) a dialkyl carbonate reactant stream, comprising greater than 80 wt.% dialkyl carbonate; and/or b) a cyclic alkylene carbonate reactant stream, comprising greater than 80 wt.% cyclic alkylene carbonate, in a first reaction zone in the presence of a homogeneous transesterification catalyst so as to form a reaction mixture; (ii) separating at least a portion of the alcohol by-product formed from the reaction of dialkyl carbonate and/or cyclic alkylene carbonate with glycerol in step (i) from the reaction mixture so as to obtain an alcohol-containing by-product stream; (iii) reacting at least a portion of the remaining reactants in the reaction mixture after alcohol by-product removal in step (ii) in a second reaction zone in the presence of the homogeneous transesterification catalyst; and (iv) obtaining a glycerol carbonate product stream; wherein the first reaction zone and the second reaction zone refer to distinct and separate reaction regions within a system/apparatus where the reactions according to steps (i) and (iii) are separately conducted. (i) contacting and partially reacting a glycerol reactant stream with: a) a dialkyl carbonate reactant stream, comprising greater than 80 wt.% dialkyl carbonate; and/or b) a cyclic alkylene carbonate reactant stream, comprising greater than 80 wt.% cyclic alkylene carbonate, in a first reaction zone in the presence of a homogeneous transesterification catalyst so as to form a reaction mixture; (ii) separating at least a portion of the alcohol by-product formed from the reaction of dialkyl carbonate and/or cyclic alkylene carbonate with glycerol in step (i) from the reaction mixture so as to obtain an alcohol-containing by-product stream; (iii) reacting at least a portion of the remaining reactants in the reaction mixture after alcohol by-product removal in step (ii) in a second reaction zone in the presence of the homogeneous transesterification catalyst; and (iv) obtaining a glycerol carbonate product stream;
An intradermal needle comprising: a needle tube having a needle tip that can be punctured into a living body; a needle hub that is adapted to support the needle tube; a wide diameter part that extends like a flange from the needle hub; a ring protrusion that extends to a front end side of the wide diameter part, and is formed into a cylindrical shape that surrounds a periphery of the needle tube; and a protector pivotably attached to the wide diameter part, so as to be movable from an open position near the needle hub to a closed position where the needle tip is covered; the protector including: an pivoting axle part arranged within a circular region having the same diameter as a diameter of the wide diameter part; a lid formed to give a width smaller than a diameter of the wide diameter part; and an arm that is pivotably supported by the pivoting axle part, characterized in that the arm is adapted to keep the lid in the open position away from the pivoting axle part and near an axis of the needle hub, and the protector further comprises a cutout that is adapted to house a part of the needle hub in the open position, formed at a part closer to the pivoting axle part of the lid. a needle tube having a needle tip that can be punctured into a living body; a needle hub that is adapted to support the needle tube; a wide diameter part that extends like a flange from the needle hub; a ring protrusion that extends to a front end side of the wide diameter part, and is formed into a cylindrical shape that surrounds a periphery of the needle tube; and a protector pivotably attached to the wide diameter part, so as to be movable from an open position near the needle hub to a closed position where the needle tip is covered; the protector including: an pivoting axle part arranged within a circular region having the same diameter as a diameter of the wide diameter part; a lid formed to give a width smaller than a diameter of the wide diameter part; and an arm that is pivotably supported by the pivoting axle part, characterized in that the arm is adapted to keep the lid in the open position away from the pivoting axle part and near an axis of the needle hub, and the protector further comprises a cutout that is adapted to house a part of the needle hub in the open position, formed at a part closer to the pivoting axle part of the lid. an pivoting axle part arranged within a circular region having the same diameter as a diameter of the wide diameter part; a lid formed to give a width smaller than a diameter of the wide diameter part; and an arm that is pivotably supported by the pivoting axle part, characterized in that the arm is adapted to keep the lid in the open position away from the pivoting axle part and near an axis of the needle hub, and the protector further comprises a cutout that is adapted to house a part of the needle hub in the open position, formed at a part closer to the pivoting axle part of the lid.