A medicine packaging apparatus, comprising: a medicine supply means for supplying a medicine according to a prescription data; a medicine standby means for temporarily holding the medicine supplied by the medicine supply means and having the medicine stand by; a printing means for printing a relevant data on a packaging paper according to the prescription data; a packaging paper conveyance means for conveying the packaging paper; a medicine packaging means for packaging the medicine supplied by the medicine supply means into the packaging paper in a packaging position; characterized by comprising a medicine detecting means (8d,13a/b/c) for detecting the medicine supplied to the medicine standby means by the medicine supply means, and comprising a counting sensor mounted in a tablet passage of a tablet cassette of the medicine supply means, and a control means for allowing the packaging paper conveyance means to convey a relevant portion of the packaging paper, on which the relevant data is printed by the printing means, to the packaging position and allowing the medicine packaging means to package the corresponding medicine standing by in the medicine standby means, wherein the control means determines whether the medicine stands by in the medicine standby means based on a detection signal from the medicine detecting means, wherein the apparatus further comprises a memory means storing a data correlating to a position information of each of a plurality medicine accommodating portions of a medicine supply means and a medicine information of the medicine accommodated in each of the medicine accommodating portions, wherein the medicine information includes use-by dates of the medicines accommodated in the medicine accommodating portions, and wherein the control means allows the printing means to print the use-by date of the medicine on the packaging paper with reference to the data stored in the memory means when the control means determines the medicine standing by in the medicine standby means to be appropriate based on a detection result from the medicine detecting means. a medicine supply means for supplying a medicine according to a prescription data; a medicine standby means for temporarily holding the medicine supplied by the medicine supply means and having the medicine stand by; a printing means for printing a relevant data on a packaging paper according to the prescription data; a packaging paper conveyance means for conveying the packaging paper; a medicine packaging means for packaging the medicine supplied by the medicine supply means into the packaging paper in a packaging position; characterized by comprising a medicine detecting means (8d,13a/b/c) for detecting the medicine supplied to the medicine standby means by the medicine supply means, and comprising a counting sensor mounted in a tablet passage of a tablet cassette of the medicine supply means, and a control means for allowing the packaging paper conveyance means to convey a relevant portion of the packaging paper, on which the relevant data is printed by the printing means, to the packaging position and allowing the medicine packaging means to package the corresponding medicine standing by in the medicine standby means, wherein the control means determines whether the medicine stands by in the medicine standby means based on a detection signal from the medicine detecting means, wherein the apparatus further comprises a memory means storing a data correlating to a position information of each of a plurality medicine accommodating portions of a medicine supply means and a medicine information of the medicine accommodated in each of the medicine accommodating portions, wherein the medicine information includes use-by dates of the medicines accommodated in the medicine accommodating portions, and wherein the control means allows the printing means to print the use-by date of the medicine on the packaging paper with reference to the data stored in the memory means when the control means determines the medicine standing by in the medicine standby means to be appropriate based on a detection result from the medicine detecting means.