A process for automatically washing fluid lines (2, 7, 8) of a fluidic system for combining liquid samples with one or more reagents, said system being provided with at least one main line connected to a plurality of reagent lines for feeding reagents, each of which being connectable to a reagent container or a cleaning container in an exchangeable manner by a fluidic connector, at least one sample intake for intaking samples and at least one pressure actuator for generating a positive or negative pressure in said fluid lines, said process comprising the steps of one or more procedures selected from the group of procedures consisting of procedure I: drawing wash fluid from a wash fluid reservoir connected to said main line via a fluid connection different from said reagent lines into said main line and discharging wash fluid into a waste compartment of a cleaning container, wherein the waste compartment is for receiving waste fluid and wherein the cleaning container is connected to at least one reagent line by said fluidic connector; procedure II: drawing wash fluid from at least one fluid compartment of at least one cleaning container into said main line, wherein the fluid compartment contains wash fluid and wherein the cleaning container is connected to at least one reagent line by said fluidic connector, and discharging wash fluid from said main line into at least one waste compartment for receiving waste fluid of said cleaning container through said at least one reagent line; procedure III: drawing wash fluid from at least one fluid compartment of at least one first cleaning container into said main line, wherein the fluid compartment contains wash fluid and wherein the at least one first cleaning container is connected to at least one first reagent line and discharging wash fluid from said main line into at least one waste compartment of at least one second cleaning container, wherein the waste compartment is for receiving waste fluid and wherein the at least one second cleaning container is connected to at least one second reagent line being different from said at least one first reagent line; procedure IV: connecting at least one cleaning container provided with at least one fluid compartment containing wash fluid to at least one reagent line, drawing wash fluid from said fluid compartment into said main line and discharging wash fluid from said main line through a waste fluid port of said main line. procedure I: drawing wash fluid from a wash fluid reservoir connected to said main line via a fluid connection different from said reagent lines into said main line and discharging wash fluid into a waste compartment of a cleaning container, wherein the waste compartment is for receiving waste fluid and wherein the cleaning container is connected to at least one reagent line by said fluidic connector; procedure II: drawing wash fluid from at least one fluid compartment of at least one cleaning container into said main line, wherein the fluid compartment contains wash fluid and wherein the cleaning container is connected to at least one reagent line by said fluidic connector, and discharging wash fluid from said main line into at least one waste compartment for receiving waste fluid of said cleaning container through said at least one reagent line; procedure III: drawing wash fluid from at least one fluid compartment of at least one first cleaning container into said main line, wherein the fluid compartment contains wash fluid and wherein the at least one first cleaning container is connected to at least one first reagent line and discharging wash fluid from said main line into at least one waste compartment of at least one second cleaning container, wherein the waste compartment is for receiving waste fluid and wherein the at least one second cleaning container is connected to at least one second reagent line being different from said at least one first reagent line; procedure IV: connecting at least one cleaning container provided with at least one fluid compartment containing wash fluid to at least one reagent line, drawing wash fluid from said fluid compartment into said main line and discharging wash fluid from said main line through a waste fluid port of said main line.