mhurhangee/ep-ind-claims huggingface dataset:
A computer-implemented method for calculating a future position of an intraoral object of a patient's intraoral cavity, the method comprising: receiving first digital data representative of an actual state of the patient's intraoral cavity at a first time point; receiving second digital data representative of an actual state of the patient's intraoral cavity at a second time point different from the first time point; processing data including the first and second digital data (302, 304) so as to determine a change in position of the intraoral object of the patient's intraoral cavity between the first time point and the second time point; determining a future position of the intraoral object at a future time point based on the determined change in position, wherein the future position is determined prior to the intraoral object being in the future position; determining a future condition of the patient's intraoral cavity based on the future position of the intraoral object, wherein the future condition comprises an undesirable dental or orthodontic condition that is predicted to occur at the future time point, and wherein the future condition is determined prior to occurrence of the future condition; providing, to a dental practitioner, third digital data, wherein the third digital data comprises an indication that the undesirable dental or orthodontic condition occurs. receiving first digital data representative of an actual state of the patient's intraoral cavity at a first time point; receiving second digital data representative of an actual state of the patient's intraoral cavity at a second time point different from the first time point; processing data including the first and second digital data (302, 304) so as to determine a change in position of the intraoral object of the patient's intraoral cavity between the first time point and the second time point; determining a future position of the intraoral object at a future time point based on the determined change in position, wherein the future position is determined prior to the intraoral object being in the future position; determining a future condition of the patient's intraoral cavity based on the future position of the intraoral object, wherein the future condition comprises an undesirable dental or orthodontic condition that is predicted to occur at the future time point, and wherein the future condition is determined prior to occurrence of the future condition; providing, to a dental practitioner, third digital data, wherein the third digital data comprises an indication that the undesirable dental or orthodontic condition occurs.
A method for producing a variable light domain that binds specifically to a target antigen, the method comprising: a) providing a library of chimeric, unpaired VL domains, wherein diversity lies in the FR1-FR3 regions of the VL domains, and wherein each member of the library comprises the CDR3 region sequence from the VL domain of a reference antibody that binds specifically to the target antigen; b) contacting the library with the target antigen; and c) selecting from the library at least one chimeric, unpaired VL domain that binds specifically to the target antigen, thereby producing a VL domain that binds specifically to the target antigen. a) providing a library of chimeric, unpaired VL domains, wherein diversity lies in the FR1-FR3 regions of the VL domains, and wherein each member of the library comprises the CDR3 region sequence from the VL domain of a reference antibody that binds specifically to the target antigen; b) contacting the library with the target antigen; and c) selecting from the library at least one chimeric, unpaired VL domain that binds specifically to the target antigen, thereby producing a VL domain that binds specifically to the target antigen.
A method for transmitting feedback, the method comprising: generating, by a user device (110, 112, 210, 305, 355, 1005, 1115, 1510, 1600) explicit channel feedback for a plurality of transmit beam-receive beam combinations, TRBCs, between the user device and a transmit-receive point, TRP (105, 205, 310, 360, 1010, 1110, 1470a, 1470b, 1570, 1600); generating, by the user device, a modified resource in accordance with explicit feedback configuration information, the modified resource configured to convey the explicit channel feedback, wherein an explicit channel feedback associated with each TRBC is conveyed on a different data symbol of the modified resource; and transmitting, by the user device, the modified resource to the TRP using a single TRBC, wherein the modified resource is a modified sounding reference signal, SRS, resource (1055, 1150), and the explicit channel feedback associated with each TRBC is conveyed on a subset of subcarriers of a data symbol (1060, 1062) associated with the TRBC. generating, by a user device (110, 112, 210, 305, 355, 1005, 1115, 1510, 1600) explicit channel feedback for a plurality of transmit beam-receive beam combinations, TRBCs, between the user device and a transmit-receive point, TRP (105, 205, 310, 360, 1010, 1110, 1470a, 1470b, 1570, 1600); generating, by the user device, a modified resource in accordance with explicit feedback configuration information, the modified resource configured to convey the explicit channel feedback, wherein an explicit channel feedback associated with each TRBC is conveyed on a different data symbol of the modified resource; and transmitting, by the user device, the modified resource to the TRP using a single TRBC, wherein the modified resource is a modified sounding reference signal, SRS, resource (1055, 1150), and the explicit channel feedback associated with each TRBC is conveyed on a subset of subcarriers of a data symbol (1060, 1062) associated with the TRBC.
An apparatus for controlling a vehicle having a motor, comprising: a driving information sensing unit configured to sense driving information of the vehicle including an open value of an accelerator position sensor, an open value of a brake position sensor, a speed of a driving wheel, a speed of a non-driving wheel, external temperature, battery temperature, a vehicle speed, and a shift stage; a driving motor configured to generate a driving force and operated as a power generator when the vehicle is coasting to generate electric energy; an antilock brake system configured to adjust a braking force applied to a driving wheel; and a controller configured to change a coast regeneration torque subject to regenerative braking by the driving motor when the vehicle is coasting, based on at least one of a difference between a speed of a driving wheel and a speed of a non-driving wheel sensed by the driving information sensing unit, correction temperature determined based on the external temperature and the battery temperature, a friction coefficient of a road, and an operation condition of the ABS; characterized in that the controller (40 is configured to determine whether a friction coefficient of a road is calculated, when the ABS is not operated; increase the coast regeneration torque to have a first slope up to a set first coast regeneration torque based on correction temperature, when the friction coefficient of the road is not calculated. a driving information sensing unit configured to sense driving information of the vehicle including an open value of an accelerator position sensor, an open value of a brake position sensor, a speed of a driving wheel, a speed of a non-driving wheel, external temperature, battery temperature, a vehicle speed, and a shift stage; a driving motor configured to generate a driving force and operated as a power generator when the vehicle is coasting to generate electric energy; an antilock brake system configured to adjust a braking force applied to a driving wheel; and a controller configured to change a coast regeneration torque subject to regenerative braking by the driving motor when the vehicle is coasting, based on at least one of a difference between a speed of a driving wheel and a speed of a non-driving wheel sensed by the driving information sensing unit, correction temperature determined based on the external temperature and the battery temperature, a friction coefficient of a road, and an operation condition of the ABS; characterized in that the controller (40 is configured to determine whether a friction coefficient of a road is calculated, when the ABS is not operated; increase the coast regeneration torque to have a first slope up to a set first coast regeneration torque based on correction temperature, when the friction coefficient of the road is not calculated.
A receiver for an animal training system, comprising: a stimulation unit for providing at least one stimulus having a quantity of energy pulses and a stimulus pulse width; and a controller connected to said stimulation unit, said controller for receiving at least one transmitted signal and for assigning amplitude information and rate information to at least one correction signal, said stimulation unit for receiving said at least one correction signal and outputting a corresponding said stimulus having said quantity of energy pulses corresponding to said rate information, and said stimulus having said stimulus pulse width corresponding to said amplitude information. a stimulation unit for providing at least one stimulus having a quantity of energy pulses and a stimulus pulse width; and a controller connected to said stimulation unit, said controller for receiving at least one transmitted signal and for assigning amplitude information and rate information to at least one correction signal, said stimulation unit for receiving said at least one correction signal and outputting a corresponding said stimulus having said quantity of energy pulses corresponding to said rate information, and said stimulus having said stimulus pulse width corresponding to said amplitude information.
A packaged food article, comprising: a. a hermetically sealed package containing a soft shaped semi-rigid tortilla which is set into preformed 3-dimensional shape adapted to hold edible fillings, wherein the shape is other than flat and is selected from a cup, bowl, U- or square bottomed-shaped taco shell, boat or canoe, pita, flower, pie, tube, envelope, pod, bun and cone, said soft shaped tortilla being both pliable and sufficiently rigid to maintain its shape at room temperature, wherein the soft shaped semi-rigid tortilla is baked, has a moisture content of between 23% and 28%, a thickness ranging from 1 to 5 mm, a fat content of from 1 to 15%, and a water activity of 0.88 or less; and b. a headspace gas within the hermetically sealed package having an oxygen level of 4% or less, wherein the packaged food article has a shelf life of at least 6 months at room temperature storage. a. a hermetically sealed package containing a soft shaped semi-rigid tortilla which is set into preformed 3-dimensional shape adapted to hold edible fillings, wherein the shape is other than flat and is selected from a cup, bowl, U- or square bottomed-shaped taco shell, boat or canoe, pita, flower, pie, tube, envelope, pod, bun and cone, said soft shaped tortilla being both pliable and sufficiently rigid to maintain its shape at room temperature, wherein the soft shaped semi-rigid tortilla is baked, has a moisture content of between 23% and 28%, a thickness ranging from 1 to 5 mm, a fat content of from 1 to 15%, and a water activity of 0.88 or less; and b. a headspace gas within the hermetically sealed package having an oxygen level of 4% or less, wherein the packaged food article has a shelf life of at least 6 months at room temperature storage.
Lighting device, in particular for motor vehicles, comprising at least: - a first light source and first optical means for participating in the generation of a first beam with an upper cut-off: - a second light source (9, 8, 12) and second optical means (13, 14) for participating in the generation of a second beam with a lower cut-off, and - control means for controlling the first and second light sources capable of jointly switching on these first and second light sources to simultaneously generate the first and second beams, the first and second optical means being capable of projecting the first and second beams so that the lower cut-off is arranged on or below the upper cut-off to form a driving beam, the device comprising a plurality of second light sources (9, 8, 12) each capable of generating a light strip (5, 6, 16) and selectively controllable by the control means, all the light strips forming the second beam the device further comprises means for reducing the light intensity of at least one of the two beams as a function of the relative inclination of the vehicle with respect to the road on which it is travelling the device being characterized in that the means for reducing the light intensity operate a reduction whose amplitude is different for at least two of the second light sources. - a first light source and first optical means for participating in the generation of a first beam with an upper cut-off: - a second light source (9, 8, 12) and second optical means (13, 14) for participating in the generation of a second beam with a lower cut-off, and - control means for controlling the first and second light sources capable of jointly switching on these first and second light sources to simultaneously generate the first and second beams, the first and second optical means being capable of projecting the first and second beams so that the lower cut-off is arranged on or below the upper cut-off to form a driving beam,
A method for producing erythropoietin-producing cells from human pluripotent stem cells, comprising the following steps of: (i) culturing human pluripotent stem cells in a medium comprising Activin and a GSK-3β inhibitor; and (ii) culturing the human pluripotent stem cells in a medium comprising an IGF family gene product after step (i). (i) culturing human pluripotent stem cells in a medium comprising Activin and a GSK-3β inhibitor; and (ii) culturing the human pluripotent stem cells in a medium comprising an IGF family gene product after step (i).
An automatic wire tying machine with a mechanism comprising, on a supporting body of said automatic wire tying machine, a movable end portion of a hook-shaped guide, which is open inwardly to carry a flexible wire, to be closed on an abutment element so as to surround the items to be tied, wherein said movable end portion is moved by means of a kinematic system that is activated by a motor, characterized in that said kinematic system comprises a rack and a linkage, which is connected thereto with a first end and to said movable end portion with an opposite second end at a compensation spring that can be compressed after the closure of said movable end portion on said abutment element during a rotation arc of said rack with which it is intended to activate cutting means for cutting said flexible wire that separate a tie thereof to be tied around said items.
A compound of formula or a pharmaceutically acceptable salt, solvate or polymorph thereof, wherein - R 1 is a C 4-8 alkyl substituted with a hydroxyl, - the carbon of R 1 bonded to the amine in the 4-position of the quinazoline is in -configuration, - R 2 is hydrogen, deuterium, fluorine, chlorine, methyl, methoxy, cyclopropyl, trifluoromethyl, or carboxylic amide, wherein each of methyl, methoxy and cyclopropyl is optionally substituted by one or more substituents independently selected from fluorine and nitrile, - R 3 is hydrogen or deuterium, - R 4 is hydrogen, deuterium, fluorine, methyl, carboxylic ester, carboxylic amide, nitrile, cyclopropyl, C 4-7 heterocycle, or 5-membered heteroaryl group, wherein each of methyl, cyclopropyl, C 4-7 heterocycle and 5-membered heteroaryl group is optionally substituted by one or more substituents independently selected from fluorine, hydroxyl, or methyl, and - R 5 is hydrogen, deuterium, fluorine, chlorine, methyl, or methoxy, provided that at least one of R 2, R 3, R 4 and R 5 is not hydrogen. - R 1 is a C 4-8 alkyl substituted with a hydroxyl, - the carbon of R 1 bonded to the amine in the 4-position of the quinazoline is in -configuration, - R 2 is hydrogen, deuterium, fluorine, chlorine, methyl, methoxy, cyclopropyl, trifluoromethyl, or carboxylic amide, wherein each of methyl, methoxy and cyclopropyl is optionally substituted by one or more substituents independently selected from fluorine and nitrile, - R 3 is hydrogen or deuterium, - R 4 is hydrogen, deuterium, fluorine, methyl, carboxylic ester, carboxylic amide, nitrile, cyclopropyl, C 4-7 heterocycle, or 5-membered heteroaryl group, wherein each of methyl, cyclopropyl, C 4-7 heterocycle and 5-membered heteroaryl group is optionally substituted by one or more substituents independently selected from fluorine, hydroxyl, or methyl, - R 5 is hydrogen, deuterium, fluorine, chlorine, methyl, or methoxy,
A compound of Formula or a salt thereof, wherein: the two dotted lines represent either two single or two double bonds; and R 1b is present only if said two dotted lines are two single bonds; X is: (i) CR 2a R 2b or NR 2b when the two dotted lines represent two single bonds; or (ii) CR 2a or N when the two dotted lines represent two double bonds; Q is: R 1a is H, -CN, -CF 3, -CH 3, -CR 6a R 6b OH, -CH 2 CH 2 OH, -CH CH 2 OH, -CH 2 CH 2 F, -NHR 7, or -C NR 8a R 8b; R 1b, when present, is H or -CH 3, provided that if R 1a is H then R 1b is also H; R 2a is H, F, or Cl, provided that if R 1a is other than H then R 2a is H; R 2b, when present, is the same as R 2a; R 3 is F or Cl; R 4 is H, F, Cl, -OCH 3, or -OCF 3; R 5 is -CN or -C CH=CH 2; R 6a and R 6b are independently H or -CH 3; R 7 is C 1-4 alkyl; and R 8a and R 8b are independently H or -CH 3. the two dotted lines represent either two single or two double bonds; and R 1b is present only if said two dotted lines are two single bonds; X is: (i) CR 2a R 2b or NR 2b when the two dotted lines represent two single bonds; or (ii) CR 2a or N when the two dotted lines represent two double bonds; (i) CR 2a R 2b or NR 2b when the two dotted lines represent two single bonds; or (ii) CR 2a or N when the two dotted lines represent two double bonds; Q is: R 1a is H, -CN, -CF 3, -CH 3, -CR 6a R 6b OH, -CH 2 CH 2 OH, -CH CH 2 OH, -CH 2 CH 2 F, -NHR 7, or -C NR 8a R 8b; R 1b, when present, is H or -CH 3, provided that if R 1a is H then R 1b is also H; R 2a is H, F, or Cl, provided that if R 1a is other than H then R 2a is H; R 2b, when present, is the same as R 2a; R 3 is F or Cl; R 4 is H, F, Cl, -OCH 3, or -OCF 3; R 5 is -CN or -C CH=CH 2; R 6a and R 6b are independently H or -CH 3; R 7 is C 1-4 alkyl; and R 8a and R 8b are independently H or -CH 3.
Display element comprising: - a semi-reflective panel formed from a transparent plate having two main faces (101A, 101B) that are joined by an edge face, this panel making it possible to view, by reflection from one of said two main faces, an image to be displayed, and - a first light source and a second light source, each placed facing an entrance face formed on said edge face, and emitting a first light beam and a second light beam, respectively, said entrance face having, facing the first light source, a first orientation so that the first light beam has a first average direction of propagation (XA') in the panel, characterized in that said entrance face has, facing the second light source, a second orientation different from the first orientation so that the second light beam has a second average direction of propagation (XB') in the panel that is different from the first average direction of propagation (XA') and wherein said entrance face has, facing the second light source, a first facet that is inclined with respect to a midplane defined by this entrance face, said second orientation corresponding to the orientation of this first facet, this first facet being inclined so as to deviate, by refraction, the second light beam, when this beam enters into the panel, in the direction of a region of the edge face of the panel that extends from a first end of the entrance face and wherein the first facet is defined in a notch produced in the semi-reflective panel facing the second light source. - a semi-reflective panel formed from a transparent plate having two main faces (101A, 101B) that are joined by an edge face, this panel making it possible to view, by reflection from one of said two main faces, an image to be displayed, and - a first light source and a second light source, each placed facing an entrance face formed on said edge face, and emitting a first light beam and a second light beam, respectively,
A switching apparatus for gas valves being used in gas cookers and heaters, comprising a support part having a top unit on which an ignition switch is provided, wherein the support part further comprising a locking tab engaging the auxiliary switch and a valve locking tab engaging the gas valve; the supporting part is formed in one piece with a top unit so as to allow switches that are different than the ignition switch to be mounted thereon, characterised in that the valve locking tab and the locking tab are extending opposite to each other on the support part.
Apparatus for determining an implant orientation of a donor cornea lens in a receiving stromal bed, comprising: a lighting device (3; 103), configured to send a first light beam (F1; F1') to a donor cornea lens (12; 112) to be implanted in a stromal receiving bed of a patient, when the donor cornea lens (12; 112) is arranged in an observation seat (11; 111); a light intensity detector device (6; 106), arranged so as to receive a second light beam (F2; F2'), transmitted through the donor cornea lens (12; 112) placed in the observation seat (11; 111) and illuminated by the first light beam (F2; F2'); a control unit (8; 108) coupled to the light intensity detector device (6; 106) and configured to acquire a plurality light intensity values, corresponding to respective orientations of the donor cornea lens (12; 112); the apparatus being characterised in that the control unit is configured to determine an implant orientation of the donor cornea lens (12; 112) as a function of the acquired light intensity values. a lighting device (3; 103), configured to send a first light beam (F1; F1') to a donor cornea lens (12; 112) to be implanted in a stromal receiving bed of a patient, when the donor cornea lens (12; 112) is arranged in an observation seat (11; 111); a light intensity detector device (6; 106), arranged so as to receive a second light beam (F2; F2'), transmitted through the donor cornea lens (12; 112) placed in the observation seat (11; 111) and illuminated by the first light beam (F2; F2'); a control unit (8; 108) coupled to the light intensity detector device (6; 106) and configured to acquire a plurality light intensity values, corresponding to respective orientations of the donor cornea lens (12; 112); the apparatus being characterised in that the control unit is configured to determine an implant orientation of the donor cornea lens (12; 112) as a function of the acquired light intensity values.
A method of developing tree seedlings comprising: germinating seeds on the surface of a growing medium to obtain the seedlings; and air pruning the seedling roots at a depth of 7.6 cm (3 inches) to achieve an improved root mass, wherein the growing medium comprises 40% composted rice hulls, 40% pine bark, and 20% sand, resulting in a 35% air space, or comprises 35% composted rice hulls, 35% pine bark, 20% sand, and 10% manure, resulting in a 35% air space. germinating seeds on the surface of a growing medium to obtain the seedlings; and air pruning the seedling roots at a depth of 7.6 cm (3 inches) to achieve an improved root mass, wherein the growing medium comprises 40% composted rice hulls, 40% pine bark, and 20% sand, resulting in a 35% air space, or comprises 35% composted rice hulls, 35% pine bark, 20% sand, and 10% manure, resulting in a 35% air space.