A method of operating a wind turbine including a rotor comprising a wind turbine blade and having a substantially horizontal rotor shaft, the rotor comprising a hub, from which the blade extends substantially in a radial direction when mounted to the hub, the blade comprising: - a profiled contour comprising a pressure side and a suction side as well as a leading edge and a trailing edge with a chord extending between the leading edge and the trailing edge, the profiled contour generating a lift when being impacted by an incident airflow, - the profiled contour in the radial direction being divided into a root region (130, 230, 330) with a substantially circular or elliptical profile closest to the hub, an airfoil region (134, 234, 334) with a lift generating profile furthest away from the hub, and a transition region (132, 232, 332) between the root region (130, 230, 330) and the airfoil region (134, 234, 334), the transition region (132, 232, 332) having a profile gradually changing in the radial direction from the circular or elliptical profile of the root region (130, 230, 330) to the lift generating profile of the airfoil region (134, 234, 334), wherein - the airfoil region (134, 234, 334) comprises a first base part (141, 241, 341) having a leading edge and a trailing edge with a chord extending between the leading edge and the trailing edge, the first base part of the airfoil region (134, 234, 334) further being divided into at least a first longitudinal segment (140, 240, 340) and a second longitudinal segment (242, 342), the first longitudinal segment (140, 240, 340) extending along at least 20% of a longitudinal extent of the airfoil region (134, 234, 334) characterised in that the first base part (141, 241, 341) has a profile with an inherent non-ideal aerodynamic design so that a substantial longitudinal part of the base part (141, 241, 341) without flow altering devices at a design point deviates from a target axial induction factor, wherein the method comprises the step of: a) adjusting a pitch of the blade and a rotational speed of the rotor so that the first base part meets the target axial induction factor in the second longitudinal segment (242, 342) without flow altering devices, and wherein the first base part in the first longitudinal segment (140, 240, 340) is provided with flow altering devices so as to meet the target axial induction factor in the first longitudinal segment (140, 240, 340). - a profiled contour comprising a pressure side and a suction side as well as a leading edge and a trailing edge with a chord extending between the leading edge and the trailing edge, the profiled contour generating a lift when being impacted by an incident airflow, - the profiled contour in the radial direction being divided into a root region (130, 230, 330) with a substantially circular or elliptical profile closest to the hub, an airfoil region (134, 234, 334) with a lift generating profile furthest away from the hub, and a transition region (132, 232, 332) between the root region (130, 230, 330) and the airfoil region (134, 234, 334), the transition region (132, 232, 332) having a profile gradually changing in the radial direction from the circular or elliptical profile of the root region (130, 230, 330) to the lift generating profile of the airfoil region (134, 234, 334), wherein - the airfoil region (134, 234, 334) comprises a first base part (141, 241, 341) having a leading edge and a trailing edge with a chord extending between the leading edge and the trailing edge, the first base part of the airfoil region (134, 234, 334) further being divided into at least a first longitudinal segment (140, 240, 340) and a second longitudinal segment (242, 342), the first longitudinal segment (140, 240, 340) extending along at least 20% of a longitudinal extent of the airfoil region (134, 234, 334) characterised in that the first base part (141, 241, 341) has a profile with an inherent non-ideal aerodynamic design so that a substantial longitudinal part of the base part (141, 241, 341) without flow altering devices at a design point deviates from a target axial induction factor, wherein the method comprises the step of: a) adjusting a pitch of the blade and a rotational speed of the rotor so that the first base part meets the target axial induction factor in the second longitudinal segment (242, 342) without flow altering devices, and wherein the first base part in the first longitudinal segment (140, 240, 340) is provided with flow altering devices so as to meet the target axial induction factor in the first longitudinal segment (140, 240, 340). a) adjusting a pitch of the blade and a rotational speed of the rotor so that the first base part meets the target axial induction factor in the second longitudinal segment (242, 342) without flow altering devices, and wherein