mhurhangee/ep-ind-claims huggingface dataset:
A compound of the formula or a pharmaceutically acceptable salt thereof, wherein: each R' is independently selected from H and QR 1; each Q is independently selected from a bond, CO, CO 2, NH, S, SO, SO 2 or O; each R 1 is independently selected from H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, aryl, heteroaryl, C 1 -C 10 cycloalkyl, halogen, C 1 -C 10 alkylaryl, C 1 -C 10 alkyl heteroaryl or C 1 -C 10 heterocycloalkyl; each L is independently selected from a 5 to 10-membered nitrogen-containing heteroaryl; W is the zinc-binding group -CONHOH of structure: each R 2 is independently hydrogen or C 1 to C 6 alkyl; and R 3 is an aryl or heteroaryl; each aryl or heteroaryl may be substituted by up to three substituents selected from C 1 -C 6 alkyl, hydroxy, C 1 -C 3 hydroxyalkyl, C 1 -C 3 alkoxy, C 1 -C 3 haloalkoxy, amino, C 1 -C 3 mono alkylamino, C 1 -C 3 bis alkylamino, C 1 -C 3 acylamino, C 1 -C 3 aminoalkyl, mono (C 1 -C 3 alkyl) amino C 1 -C 3 alkyl, bis(C 1 -C 3 alkyl) amino C 1 -C 3 alkyl, C 1 -C 3 -acylamino, C 1 -C 3 alkyl sulfonylamino, halo, nitro, cyano, trifluoromethyl, carboxy, C 1 -C 3 alkoxycarbonyl, aminocarbonyl, mono C 1 -C 3 alkyl aminocarbonyl, bis C 1 -C 3 alkyl aminocarbonyl, -SO 3 H, C 1 -C 3 alkylsulfonyl, aminosulfonyl, mono C 1 -C 3 alkyl aminosulfonyl and bis C 1 -C 3 -alkyl aminosulfonyl; and each alkyl, alkenyl or alkynyl may be substituted with halogen, NH 2, NO 2 or hydroxyl. each R' is independently selected from H and QR 1; each Q is independently selected from a bond, CO, CO 2, NH, S, SO, SO 2 or O; each R 1 is independently selected from H, C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, aryl, heteroaryl, C 1 -C 10 cycloalkyl, halogen, C 1 -C 10 alkylaryl, C 1 -C 10 alkyl heteroaryl or C 1 -C 10 heterocycloalkyl; each L is independently selected from a 5 to 10-membered nitrogen-containing heteroaryl; W is the zinc-binding group -CONHOH of structure: each R 2 is independently hydrogen or C 1 to C 6 alkyl; and R 3 is an aryl or heteroaryl; each aryl or heteroaryl may be substituted by up to three substituents selected from C 1 -C 6 alkyl, hydroxy, C 1 -C 3 hydroxyalkyl, C 1 -C 3 alkoxy, C 1 -C 3 haloalkoxy, amino, C 1 -C 3 mono alkylamino, C 1 -C 3 bis alkylamino, C 1 -C 3 acylamino, C 1 -C 3 aminoalkyl, mono (C 1 -C 3 alkyl) amino C 1 -C 3 alkyl, bis(C 1 -C 3 alkyl) amino C 1 -C 3 alkyl, C 1 -C 3 -acylamino, C 1 -C 3 alkyl sulfonylamino, halo, nitro, cyano, trifluoromethyl, carboxy, C 1 -C 3 alkoxycarbonyl, aminocarbonyl, mono C 1 -C 3 alkyl aminocarbonyl, bis C 1 -C 3 alkyl aminocarbonyl, -SO 3 H, C 1 -C 3 alkylsulfonyl, aminosulfonyl, mono C 1 -C 3 alkyl aminosulfonyl and bis C 1 -C 3 -alkyl aminosulfonyl; and each alkyl, alkenyl or alkynyl may be substituted with halogen, NH 2, NO 2 or hydroxyl.
A method of forming a structural oil pan via lost core molding, the structural oil pan is made of polymeric material comprising a single-piece bracket portion integral with the structural oil pan configured for mounting to a vehicle, a pan portion integrated and integrally formed with the single-piece bracket portion and defining an oil reservoir, wherein the bracket portion and the pan portion are co-molded together to form the structural oil pan, characterized in that said structural oil pan comprises a structural section formed via the lost core molding and defining a closed cavity, said method comprising the steps of: I. lost core molding by; forming a metal core; molding the single-piece bracket portion and/or the pan portion about the metal core; and removing the metal core to form the structural section with said closed cavity therein in at least one of the single piece bracket portion and the pan portion. I. lost core molding by; forming a metal core; molding the single-piece bracket portion and/or the pan portion about the metal core; and removing the metal core to form the structural section with said closed cavity therein in at least one of the single piece bracket portion and the pan portion.
A liquid crystal composition having a nematic phase and including at least one compound selected from the group of compounds represented by formula as a first component, at least one compound selected from the group of compounds represented by formula as a second component and at least one compound selected from the group of compounds represented by formula as a third component: wherein R 1 and R 2 are independently alkyl having 1 to 12 carbons, alkoxy having 1 to 12 carbons or alkenyl having 2 to 12 carbons; R 3 and R 4 are independently alkyl having 1 to 12 carbons, alkoxy having 1 to 12 carbons, alkenyl having 2 to 12 carbons, or alkenyl having 2 to 12 carbons in which arbitrary hydrogen is replaced by fluorine; ring A and ring B are independently 1,4-cyclohexylene or 1,4-phenylene; ring C and ring D are independently 1,4-cyclohexylene, 1,4-phenylene, 3-fluoro-1,4-phenylene or 3,5-difluoro-1,4-phenylene; ring E, ring F, ring G and ring H are independently 1,4-cyclohexylene, 1,4-phenylene, 2-fluoro-1,4-phenylene, 3-fluoro-1,4-phenylene or 2,5-difluoro-1,4-phenylene; Z 1, Z 2 and Z 3 are independently a single bond, ethylene or carbonyloxy; X 1 and X 2 are independently hydrogen or fluorine; and Y 1 is fluorine, chlorine or trifluoromethoxy, and wherein the ratio of the first component is in the range of 5% by weight to 40% by weight, the ratio of the second component is in the range of 5% by weight to 30% by weight, and the ratio of the third component is in the range of 5% by weight to 30% by weight, based on the total weight of the liquid crystal composition.
A continuous compression molding machine comprising: a tooling die extending through a heating zone and a cooling zone; a tooling sleeve corresponding to the tooling die for forming a thermoplastic composite part from a thermoplastic composite charge when the tooling sleeve with the thermoplastic composite charge is moved with respect to the tooling die through the heating zone and the cooling zone; and a biasing system configured to hold the thermoplastic composite charge at a first angle within the heating zone and hold the thermoplastic composite charge at a second angle within the cooling zone as the tooling sleeve moves through the heating zone and the cooling zone with the thermoplastic composite charge, wherein the first angle is different from the second angle. a tooling die extending through a heating zone and a cooling zone; a tooling sleeve corresponding to the tooling die for forming a thermoplastic composite part from a thermoplastic composite charge when the tooling sleeve with the thermoplastic composite charge is moved with respect to the tooling die through the heating zone and the cooling zone; and a biasing system configured to hold the thermoplastic composite charge at a first angle within the heating zone and hold the thermoplastic composite charge at a second angle within the cooling zone as the tooling sleeve moves through the heating zone and the cooling zone with the thermoplastic composite charge, wherein the first angle is different from the second angle.
A turbine engine fan case assembly comprising: a structural case; a liner assembly; and a radially accommodating attachment system connecting the liner assembly to the structural case and characterized by comprising: a circumferentially-distributed plurality of longitudinally elongate radially outwardly open channels mounted to the liner assembly; and an associated plurality of inwardly-projecting tongues mounted to the structural case, each tongue accommodated in an associated said channel; and in that: the structural case comprises a non metallic member principally dictating thermal expansion of the structural case; and the liner assembly comprises a metallic member principally dictating thermal expansion of the liner assembly. a structural case; a liner assembly; and a radially accommodating attachment system connecting the liner assembly to the structural case and characterized by comprising: a circumferentially-distributed plurality of longitudinally elongate radially outwardly open channels mounted to the liner assembly; and an associated plurality of inwardly-projecting tongues mounted to the structural case, each tongue accommodated in an associated said channel; and in that: the structural case comprises a non metallic member principally dictating thermal expansion of the structural case; and the liner assembly comprises a metallic member principally dictating thermal expansion of the liner assembly. a circumferentially-distributed plurality of longitudinally elongate radially outwardly open channels mounted to the liner assembly; and an associated plurality of inwardly-projecting tongues mounted to the structural case, each tongue accommodated in an associated said channel; and in that: the structural case comprises a non metallic member principally dictating thermal expansion of the structural case; and the liner assembly comprises a metallic member principally dictating thermal expansion of the liner assembly.
A method of fabricating a thin film gas sensor device comprising: providing a substrate; supporting a first electrode with the substrate; supporting a second electrode with the substrate; forming a nanostructured thin film layer; and operably connecting the first and the second electrode to the nanostructured thin film layer, characterized in that forming the nanostructured thin film layer comprises: forming a silicon dioxide seed layer above the substrate; structuring the seed layer by ion-milling or chemically activating the seed layer to encourage the spaced-apart nucleation of the plurality of grains of the nanostructured thin film layer;and forming the nanostructured thin film layer from lanthanum oxide using atomic layer deposition directly on the seed layer. providing a substrate; supporting a first electrode with the substrate; supporting a second electrode with the substrate; forming a nanostructured thin film layer; and operably connecting the first and the second electrode to the nanostructured thin film layer, characterized in that forming the nanostructured thin film layer comprises: forming a silicon dioxide seed layer above the substrate; structuring the seed layer by ion-milling or chemically activating the seed layer to encourage the spaced-apart nucleation of the plurality of grains of the nanostructured thin film layer;and forming the nanostructured thin film layer from lanthanum oxide using atomic layer deposition directly on the seed layer. forming a silicon dioxide seed layer above the substrate; structuring the seed layer by ion-milling or chemically activating the seed layer to encourage the spaced-apart nucleation of the plurality of grains of the nanostructured thin film layer;and forming the nanostructured thin film layer from lanthanum oxide using atomic layer deposition directly on the seed layer.
A method of detecting pancreatic cancer distinguishably from chronic pancreatitis, comprising measuring glycoprotein C4BPA contained in a sample and correlating an amount of the C4BPA with detection of pancreatic cancer, wherein the sample is serum, blood plasma, blood or urine.
A hot-stamped steel comprising, by mass%: C: 0.20% to 0.35%; Si: 0.1% to 0.5%; a total of at least one selected from Mn and Cr: 1% to 3%; Al: 0.005% to 0.06%; Ti: 0.002% to 0.1%; Nb: 0.002% to 0.1%; O: 0.003% to 0.007%; optionally further comprising, by mass%, one or more of: B: 0.005% or less; V: 0.1% or less; Mo: 0.5% or less; Ca: 0.03% or less; Mg: 0.03% or less; REM: 0.03% or less; Cu: 0.5% or less; Sn: 0.1% or less; Ni: 0.5% or less; and W: 1% or less; and a balance of iron and inevitable impurities, wherein an amount of P is limited to 0.015% or less, an amount of S is limited to 0.01% or less, an amount of N is limited to 0.004% or less, a dimensional ratio of lengths of prior austenite grains in a rolling direction to the lengths of the prior austenite grains in a sheet thickness direction is 1.3 to 2.5, an average grain size of the prior austenite grains is 6 μm or less, a microstructure includes 98% or more of martensite, and a tensile strength is 1470 MPa or more. C: 0.20% to 0.35%; Si: 0.1% to 0.5%; a total of at least one selected from Mn and Cr: 1% to 3%; Al: 0.005% to 0.06%; Ti: 0.002% to 0.1%; Nb: 0.002% to 0.1%; O: 0.003% to 0.007%; optionally further comprising, by mass%, one or more of: B: 0.005% or less; V: 0.1% or less; Mo: 0.5% or less; Ca: 0.03% or less; Mg: 0.03% or less; REM: 0.03% or less; Cu: 0.5% or less; Sn: 0.1% or less; Ni: 0.5% or less; and W: 1% or less; and B: 0.005% or less; V: 0.1% or less; Mo: 0.5% or less; Ca: 0.03% or less; Mg: 0.03% or less; REM: 0.03% or less; Cu: 0.5% or less; Sn: 0.1% or less; Ni: 0.5% or less; and W: 1% or less; and a balance of iron and inevitable impurities, wherein an amount of P is limited to 0.015% or less, an amount of S is limited to 0.01% or less, an amount of N is limited to 0.004% or less, a dimensional ratio of lengths of prior austenite grains in a rolling direction to the lengths of the prior austenite grains in a sheet thickness direction is 1.3 to 2.5, an average grain size of the prior austenite grains is 6 μm or less, a microstructure includes 98% or more of martensite, and a tensile strength is 1470 MPa or more.
A method of determining at least one geometrical characteristic of a tank arrangement (10, 50) for a ship, the tank arrangement (10, 50, 60, 230, 330) comprising a number of tanks (103, 503) having tank walls comprising wall plates (100, 102, 500, 502), the method comprising a step of: (a) defining the number of tanks (103, 503) or tank wall plates (100, 102, 500, 502); and characterized by further comprising a step of: (b) determining the geometrical characteristic based upon said defined number of tanks (103, 503) or tank wall plates (100, 102, 500, 502) by: evaluating any one or more of the equations: L = Vx 2 2 ⁢ y 1 / 3; B = Vy 2 2 ⁢ x 1 / 3; and D = 4 ⁢ V xy 1 / 3; or computer-implementing said equations; or using a result obtained from evaluating any one of said equations or from said computer implementation; wherein L is an overall length of the tank arrangement (10, 50), B is an overall breadth of the tank arrangement (10, 50), D is an overall depth of the tank arrangement, V is an overall volume of the tank arrangement (10, 50), x is the number of tank wall plates (100, 500) in a first horizontal direction and y is the number of tank wall plates (102, 502) in a second horizontal direction which is orthogonal to the first horizontal direction. (a) defining the number of tanks (103, 503) or tank wall plates (100, 102, 500, 502); evaluating any one or more of the equations: L = Vx 2 2 ⁢ y 1 / 3; B = Vy 2 2 ⁢ x 1 / 3; and D = 4 ⁢ V xy 1 / 3; or computer-implementing said equations; or using a result obtained from evaluating any one of said equations or from said computer implementation; wherein L is an overall length of the tank arrangement (10, 50), B is an overall breadth of the tank arrangement (10, 50), D is an overall depth of the tank arrangement, V is an overall volume of the tank arrangement (10, 50), x is the number of tank wall plates (100, 500) in a first horizontal direction and y is the number of tank wall plates (102, 502) in a second horizontal direction which is orthogonal to the first horizontal direction.
A system comprising: a distributed network; and plurality of nodes connected to the distributed network, each node having local measurements that are independent and identical distributed samples of a random variable with an unknown distribution, wherein each node uses gossip-based distributed kernel density estimation to estimate an unknown global distribution from the distributed samples using kernel density estimation by repeatedly contacting other nodes at random to exchange information, the system being adapted to obtain the sample of the random variable with an unknown distribution from each node of the plurality of nodes in the distributed network; maintain a local kernel set of each of the nodes, the kernel set including a plurality of kernels associated with the distributed samples on the respective node; select from the plurality of nodes, a random node as a gossip target node; exchange local kernel sets from the gossip target node with each one of the remaining nodes; merge kernels of the target node and kernels of each of the remaining nodes, thereby updating the respective local kernel set of the nodes in order to approach the global distribution estimation by the respective node, determine whether the updated kernel set of a node exceeds the resources of that node; and perform a data reduction on the updated kernel set of that node if the updated kernel set exceeds the resources of that node. a distributed network; and plurality of nodes connected to the distributed network, each node having local measurements that are independent and identical distributed samples of a random variable with an unknown distribution, wherein each node uses gossip-based distributed kernel density estimation to estimate an unknown global distribution from the distributed samples using kernel density estimation by repeatedly contacting other nodes at random to exchange information, the system being adapted to obtain the sample of the random variable with an unknown distribution from each node of the plurality of nodes in the distributed network; maintain a local kernel set of each of the nodes, the kernel set including a plurality of kernels associated with the distributed samples on the respective node; select from the plurality of nodes, a random node as a gossip target node; exchange local kernel sets from the gossip target node with each one of the remaining nodes; merge kernels of the target node and kernels of each of the remaining nodes, thereby updating the respective local kernel set of the nodes in order to approach the global distribution estimation by the respective node, determine whether the updated kernel set of a node exceeds the resources of that node; and perform a data reduction on the updated kernel set of that node if the updated kernel set exceeds the resources of that node.
A system for actuating a device with rotating tools by means of a hydraulic motor, the hydraulic motor being housed with a closed circuit in a motor case, comprising an inlet line for feeding the hydraulic motor, an outlet line for the hydraulic motor, a drain line connecting the motor case with the outlet line, a non-return valve being interposed between the outlet line and the inlet line, characterized in that a tank is connected downstream of the connection between the drain line and the outlet line of the hydraulic motor, for absorbing an overpressure.
A trolley, in particular a transport trolley for receiving one or more transport containers, having a baseplate consisting of plastic, also having multiple castors (7, 8) which are connected to the underside of the baseplate, and having at least one stacking trough on the top for receiving at least one castor (7, 8) of a further trolley placed on the top of the baseplate, wherein the stacking trough has at least one drainage opening, characterised in that the stacking trough is designed as a longitudinal depression running over virtually the entire wide side of the baseplate, wherein the stacking trough is equipped with two drainage openings arranged on both sides of a supporting face.
A method for network configuration access, including: a network device joining a network management system; searching, by the network management system according to a type information of the network device, for a transport layer protocol which is supported by the network device in a transport layer architecture of a network configuration protocol (NETCONF) configuration framework of the NMS and definition information which the transport layer protocol is to use to implement a connection to the network device; establishing a NETCONF session with the network device by using said transport layer protocol and said definition information; during establishment of the NETCONF session, comparing a first NETCONF capability set which is obtained from the network device with a second NETCONF capability set that is supported by the NMS and is defined in the metadata definition file of the NETCONF configuration framework, and assigning an intersection of the first NETCONF capability set and the second NETCONF capability set, as an active capability set of the NETCONF session; and performing, by the NMS, a network configuration access to the network device based on the active capability set of the NETCONF session. a network device joining a network management system; searching, by the network management system according to a type information of the network device, for a transport layer protocol which is supported by the network device in a transport layer architecture of a network configuration protocol (NETCONF) configuration framework of the NMS and definition information which the transport layer protocol is to use to implement a connection to the network device; establishing a NETCONF session with the network device by using said transport layer protocol and said definition information; during establishment of the NETCONF session, comparing a first NETCONF capability set which is obtained from the network device with a second NETCONF capability set that is supported by the NMS and is defined in the metadata definition file of the NETCONF configuration framework, and assigning an intersection of the first NETCONF capability set and the second NETCONF capability set, as an active capability set of the NETCONF session; and performing, by the NMS, a network configuration access to the network device based on the active capability set of the NETCONF session.
System comprising a threshold, a post profile (9, 30) and a threshold holder (10, 40), - wherein the threshold has an internal tread surface, an external tread surface which is lowered with respect to the internal tread surface, and a swirl channel formed as an undercut, and - wherein the threshold holder (10, 40) has an underside (12, 46), an upper side (11, 45) and a front edge (13, 47) which corresponds to the shape of the swirl channel of the threshold, characterized in that - the threshold holder (10, 40) has on its underside (12, 46) at least one mounting protuberance (14, 48) and the threshold has, in the region of the external tread surface, at least one bore corresponding thereto, and in that - the front edge (13, 47) of the threshold holder (10, 40) is designed to be flexible. - wherein the threshold has an internal tread surface, an external tread surface which is lowered with respect to the internal tread surface, and a swirl channel formed as an undercut, and - wherein the threshold holder (10, 40) has an underside (12, 46), an upper side (11, 45) and a front edge (13, 47) which corresponds to the shape of the swirl channel of the threshold, characterized in that - the threshold holder (10, 40) has on its underside (12, 46) at least one mounting protuberance (14, 48) and the threshold has, in the region of the external tread surface, at least one bore corresponding thereto, and in that - the front edge (13, 47) of the threshold holder (10, 40) is designed to be flexible.