Rodenticidal composition, in the form of fresh paste, pellet or paraffin block, of negligible toxicity and extreme palatability, which comprises, one mixed with the other, A) at least one inorganic solidifying agent and modifier of the pH, capable of solidifying in the presence of water, selected from among hydraulic binders such as Portland cement, quick set cement, anhydrous calcium sulfate (anhydrite), calcium sulfate dihydrate [CaSO 4 ·2H 2 O], calcium sulfate hemihydrate [(CaSO 4) 2 ·H 2 O]; or mixtures thereof, B) at least one palatable inorganic or organic hygroscopic and/or hydrophilic agent which swells and increases in volume in the presence of water, changing consistency, said agent not including flours while comprising dextrins, or mixtures thereof with starch and/or cereal bran; C) at least one hydrophobic binder, palatable for rodent species, selected from - oils, butters, waxes and vegetable and/or animal fats, in liquid or solid form at room temperature; or mixtures thereof with lower quantities of paraffin fats, - paraffin fats, in the case of paraffin blocks, with the condition that their content is lower or equal to 20% in weight with respect to the weight of the total composition; D) at least one inert filler selected from charcoal, clay and silicates in general, vermiculite, or mixtures thereof; E) at least one palatable substance to increase the palatability of the bait; said component C) being in a mixture with the remaining components of said composition said palatable substance(s) B) being a coadjuvant to increase the efficacy of solidification of the solidifying agents A) in the intestinal blockage; provided that when A) is cement, B) does not contain bentonite. A) at least one inorganic solidifying agent and modifier of the pH, capable of solidifying in the presence of water, selected from among hydraulic binders such as Portland cement, quick set cement, anhydrous calcium sulfate (anhydrite), calcium sulfate dihydrate [CaSO 4 ·2H 2 O], calcium sulfate hemihydrate [(CaSO 4) 2 ·H 2 O]; or mixtures thereof, B) at least one palatable inorganic or organic hygroscopic and/or hydrophilic agent which swells and increases in volume in the presence of water, changing consistency, said agent not including flours while comprising dextrins, or mixtures thereof with starch and/or cereal bran; C) at least one hydrophobic binder, palatable for rodent species, selected from - oils, butters, waxes and vegetable and/or animal fats, in liquid or solid form at room temperature; or mixtures thereof with lower quantities of paraffin fats, - paraffin fats, in the case of paraffin blocks, with the condition that their content is lower or equal to 20% in weight with respect to the weight of the total composition; - oils, butters, waxes and vegetable and/or animal fats, in liquid or solid form at room temperature; or mixtures thereof with lower quantities of paraffin fats, - paraffin fats, in the case of paraffin blocks, with the condition that their content is lower or equal to 20% in weight with respect to the weight of the total composition; D) at least one inert filler selected from charcoal, clay and silicates in general, vermiculite, or mixtures thereof; E) at least one palatable substance to increase the palatability of the bait;