mhurhangee/ep-ind-claims huggingface dataset:
A compound having a structure wherein X is selected from the group consisting of and -SO 2 -; Y is selected from the group consisting of-NH-, -O-,-S-, and null when X is -SO 2 -: R is selected from the group consisting of wherein ring A is a C 4-8 aliphatic ring, wherein the B ring is aryl or nitrogen atom-containing heteroaryl and the B rings are optionally substituted; and R 1 is selected from the group consisting of -(CH 2) 4-10 -, -(CH 2) 1-3 CH=CH-(CH 2) 1-3 - wherein Z is O, S, or NH, and wherein n is 0, 1, or 2, and wherein the B ring is aryl or nitrogen atom-containing heteroaryl and the rings are optionally substituted; or a pharmaceutically acceptable salt, hydrate, or solvate thereof. wherein X is selected from the group consisting of and -SO 2 -; Y is selected from the group consisting of-NH-, -O-,-S-, and null when X is -SO 2 -: R is selected from the group consisting of wherein ring A is a C 4-8 aliphatic ring, wherein the B ring is aryl or nitrogen atom-containing heteroaryl and the B rings are optionally substituted; and R 1 is selected from the group consisting of -(CH 2) 4-10 -, -(CH 2) 1-3 CH=CH-(CH 2) 1-3 - wherein Z is O, S, or NH, and wherein n is 0, 1, or 2, and wherein the B ring is aryl or nitrogen atom-containing heteroaryl and the rings are optionally substituted; or a pharmaceutically acceptable salt, hydrate, or solvate thereof.
An ex vivo method for predicting recurrence and/or non-recurrence of colorectal cancer in a patient, the method comprising analysing a patient sample for quantitative expression of a prognostic genetic profile correlated with colorectal cancer recurrence, the profile comprising the expression of the nucleic acid sequences of SEQ ID NOS: 1, 2, 3, 4, and 5 and further comprises using computer software designed to apply gene expression data obtained from the patient's sample to the prognostic rule: If [(((SEQ ID NO 1/SEQ ID NO 3) X SEQ ID NO 5) - ((SEQ ID NO 2/SEQ ID NO 4) X SEQ ID NO 3)) ≥ -4.4777] then recurrence.
A sensitizer system for a radiation-curable coating material, comprising a styrylic cation D + of the formula and as counterion an anion An - selected from the group consisting of 4-hexylbenzenesulfonate, 4-octylbenzenesulfonate, 4-decylbenzenesulfonate and 4-dodecylbenzenesulfonate, in which R 1, R 5, R 6, R 7 and R 8 each independently can be hydrogen, C 1 -C 18 alkyl or C 1 -C 18 alkyloxy, R 1 can additionally be halogen, preferably bromine R 2, R 3 and R 4 each independently can be C 1 -C 18 alkyl, R 9 and R 10 each independently can be unsubstituted or aryl-, alkyl-, aryloxy-, alkyloxy-, heteroatom- and/or heterocycle-substituted C 1 -C 18 alkyl, C 6 -C 12 aryl or C 5 -C 12 cycloalkyl.
A cartridge for use with a surgical instrument, the cartridge comprising: (a) a curved body; (b) a deck defined by the curved body, wherein the deck is configured to clamp tissue against an anvil; (c) a plurality of staple openings formed in the deck, wherein the staple openings are configured to house a plurality of staples; (d) an arcuate slot formed in the deck, wherein the arcuate slot is configured to slidably receive a cutting member therethrough; (e) an opening formed in the deck adjacent to an end of the arcuate slot, wherein the opening is configured to slidably receive a pin therethrough; and (f) a raised surface offset from the deck and extending circumferentially about at least a portion of the opening, wherein the raised surface is configured to clamp tissue against the anvil to thereby fix the tissue relative to the opening. (a) a curved body; (b) a deck defined by the curved body, wherein the deck is configured to clamp tissue against an anvil; (c) a plurality of staple openings formed in the deck, wherein the staple openings are configured to house a plurality of staples; (d) an arcuate slot formed in the deck, wherein the arcuate slot is configured to slidably receive a cutting member therethrough; (e) an opening formed in the deck adjacent to an end of the arcuate slot, wherein the opening is configured to slidably receive a pin therethrough; and (f) a raised surface offset from the deck and extending circumferentially about at least a portion of the opening, wherein the raised surface is configured to clamp tissue against the anvil to thereby fix the tissue relative to the opening.
An ablation antenna device comprising: an antenna comprising an inner conductor, wherein the antenna has a proximal end and a distal end, wherein the inner conductor has a distal end and a proximal end, and a conductive metal fitting; and a conductive tip at the distal end of said antenna; wherein said inner conductor is not physically coupled to said conductive tip, wherein said inner conductor is capacitively-coupled to said conductive tip, wherein said inner conductor is hollow, wherein inside of said hollow inner conductor is a coolant channel for circulating a coolant through the inner conductor, wherein the distal end of the inner conductor is adhered to and surrounded by the conductive metal fitting, wherein the conductive tip is attached to an insulator, and wherein the insulator is attached to a distal end of the conductive metal fitting. an antenna comprising an inner conductor, wherein the antenna has a proximal end and a distal end, wherein the inner conductor has a distal end and a proximal end, and a conductive metal fitting; and a conductive tip at the distal end of said antenna; wherein said inner conductor is not physically coupled to said conductive tip, wherein said inner conductor is capacitively-coupled to said conductive tip, wherein said inner conductor is hollow, wherein inside of said hollow inner conductor is a coolant channel for circulating a coolant through the inner conductor, wherein the distal end of the inner conductor is adhered to and surrounded by the conductive metal fitting, wherein the conductive tip is attached to an insulator, and wherein the insulator is attached to a distal end of the conductive metal fitting. wherein said inner conductor is not physically coupled to said conductive tip, wherein said inner conductor is capacitively-coupled to said conductive tip, wherein said inner conductor is hollow, wherein inside of said hollow inner conductor is a coolant channel for circulating a coolant through the inner conductor, wherein the distal end of the inner conductor is adhered to and surrounded by the conductive metal fitting, wherein the conductive tip is attached to an insulator, and wherein the insulator is attached to a distal end of the conductive metal fitting.
A vacuum hold down device comprising: - a table comprising a perforated plate having a bottom side connected to a vacuum system for producing reduced pressure on said bottom side, and - a plurality of porous supports (20; 120) intended to be removably positioned on a top side of said perforated plate, each porous support comprising a perforated tray (21; 121) provided on one side (21a; 121a) with outer reliefs (23; 123) and on the other side (21b; 121b) with a blade penetrable porous structure (22; 122) fixed thereon, each porous support (20; 120) being configured to be installed on, and removed from, said top side of said perforated plate in order to install another porous support (20; 120). - a table comprising a perforated plate having a bottom side connected to a vacuum system for producing reduced pressure on said bottom side, and - a plurality of porous supports (20; 120) intended to be removably positioned on a top side of said perforated plate, each porous support comprising a perforated tray (21; 121) provided on one side (21a; 121a) with outer reliefs (23; 123) and on the other side (21b; 121b) with a blade penetrable porous structure (22; 122) fixed thereon, each porous support (20; 120) being configured to be installed on, and removed from, said top side of said perforated plate in order to install another porous support (20; 120).
A digital mixer, comprising: input means for inputting patch operations by a user; plural ports (201, 202) each receiving an audio signal from an outside and processing and outputting the audio signal according to respective parameters set to the plural ports (201, 202) respectively; plural channels each performing characteristic adjustment processing on a supplied audio signal and outputting the processed audio signal; and a patch connecting a respective one of the plural ports (201, 202) to each of the plural channels according to a patch operation by a user inputted through the input means, and supplying the audio signal of the respective one port (201, 202) to the channel connected to the respective one port (201, 202); characterized in that the digital mixer (100 further comprises a parameter applier applying, when a port connected to one channel is changed from a first port to a second port among the plural ports (201, 202) by the patch operation by the user, respective ones of the parameters set to the first port before the change to the second port such that the second port, after the change, processes the audio signal according to said respective ones of the parameters. input means for inputting patch operations by a user; plural ports (201, 202) each receiving an audio signal from an outside and processing and outputting the audio signal according to respective parameters set to the plural ports (201, 202) respectively; plural channels each performing characteristic adjustment processing on a supplied audio signal and outputting the processed audio signal; and a patch connecting a respective one of the plural ports (201, 202) to each of the plural channels according to a patch operation by a user inputted through the input means, and supplying the audio signal of the respective one port (201, 202) to the channel connected to the respective one port (201, 202); characterized in that the digital mixer (100 further comprises a parameter applier applying, when a port connected to one channel is changed from a first port to a second port among the plural ports (201, 202) by the patch operation by the user, respective ones of the parameters set to the first port before the change to the second port such that the second port, after the change, processes the audio signal according to said respective ones of the parameters.
Method for preparation of LiCoO 2 particles having an octahedral shape wherein the average particle size D50 of said LiCoO 2 particles is in the range of 3-30 μm, characterized thereof that Co 2 particles comprising octahedral shape particles, or Co 3 O 4 particles obtained from Co 2 comprising octahedral shape particles, or Co 3 O 4 particles comprising octahedral shape particles and lithium salt are heated at 800 - 1100 °C for 1 - 10 h in air or in other oxygen containing atmosphere.
A continuously variable transmission comprising: two pulleys (12, 14), each having opposing conical surfaces (24, 26; 34, 36) with a distance therebetween being variable; and a chain which is wrapped around the two pulleys (12, 14) and is clamped between the conical surfaces (24, 26; 34, 36), wherein the chain is formed by coupling chain elements, each chain element including a link unit in which a plurality of links each having an opening and placed to extend in a circumferential direction of the chain are arranged in a width direction of the chain and two pins which extend through the opening of the respective links at both ends of the link, both ends of at least one pin coming into contact with the conical surfaces (24, 26; 34, 36), in which the chain elements are coupled such that the pin of one of two chain elements that are adjacent to each other in the circumferential direction of the chain is made to pass through the opening of the link of the other chain element, and when the pin is clamped by the pulley (12, 14), a deformation ratio of pin length is defined as ΔL/(F x L), wherein: L is the free length of the pin along the centre line thereof; ΔL is the quantity of variation in the length of the pin; and F is the load from the pulley (12, 14) in the center line direction of the pin, characterized in that the deformation ratio is 1.3 x 10 -6 (1/N) or greater. two pulleys (12, 14), each having opposing conical surfaces (24, 26; 34, 36) with a distance therebetween being variable; and a chain which is wrapped around the two pulleys (12, 14) and is clamped between the conical surfaces (24, 26; 34, 36), wherein the chain is formed by coupling chain elements, each chain element including a link unit in which a plurality of links each having an opening and placed to extend in a circumferential direction of the chain are arranged in a width direction of the chain and two pins which extend through the opening of the respective links at both ends of the link, both ends of at least one pin coming into contact with the conical surfaces (24, 26; 34, 36), in which the chain elements are coupled such that the pin of one of two chain elements that are adjacent to each other in the circumferential direction of the chain is made to pass through the opening of the link of the other chain element, and when the pin is clamped by the pulley (12, 14), a deformation ratio of pin length is defined as ΔL/(F x L), wherein: L is the free length of the pin along the centre line thereof; ΔL is the quantity of variation in the length of the pin; and F is the load from the pulley (12, 14) in the center line direction of the pin, characterized in that the deformation ratio is 1.3 x 10 -6 (1/N) or greater. L is the free length of the pin along the centre line thereof; ΔL is the quantity of variation in the length of the pin; and F is the load from the pulley (12, 14) in the center line direction of the pin, characterized in that the deformation ratio is 1.3 x 10 -6 (1/N) or greater.
A calorific value measurement system configured to measure a calorific value of measurement target mixed gas, the system comprising: a heater element coming in contact with gas, the heater element being configured to generate heat at a plurality of different temperatures; a measurement module configured to measure a value of an electric signal from the heater element; a determination module configured to compare a determination value with a predetermined threshold, the determination value being based on a measured value of an electric signal from the heater element, the heater element generating heat at a first temperature out of the plurality of different temperatures, and to determine if the gas is measurement target or not based on the result of the comparison; and a calorific value calculation module configured to calculate a calorific value of the gas based on a measured value of an electric signal from the heater element if it is determined that the gas is a measurement target, wherein the predetermined threshold is set based on a value of an electric signal from the heater element, the heater element generating heat at the first temperature, when the heater element is in contact with a sample mixed gas, and also based on a value of an electric signal from the heater element when the heater element is in contact with the air. a heater element coming in contact with gas, the heater element being configured to generate heat at a plurality of different temperatures; a measurement module configured to measure a value of an electric signal from the heater element; a determination module configured to compare a determination value with a predetermined threshold, the determination value being based on a measured value of an electric signal from the heater element, the heater element generating heat at a first temperature out of the plurality of different temperatures, and to determine if the gas is measurement target or not based on the result of the comparison; and a calorific value calculation module configured to calculate a calorific value of the gas based on a measured value of an electric signal from the heater element if it is determined that the gas is a measurement target, wherein the predetermined threshold is set based on a value of an electric signal from the heater element, the heater element generating heat at the first temperature, when the heater element is in contact with a sample mixed gas, and also based on a value of an electric signal from the heater element when the heater element is in contact with the air.
Cathode shell structure for an electrolysis cell for production of aluminium according to the Hall-Héroult process, said structure comprises a shell with vertical stiffeners and horizontal webs at its outside, and further several cradle structures consisting of interconnected vertical structural elements and horizontal beams, and at least one horizontal web provided with apertures facing the shell, wherein, the apertures are represented by discrete cut-outs at the side edge of the horizontal web having bridging parts between them, the horizontal web being connected to the shell via said bridging parts whereby the apertures are facing a wall of the shell and secure sufficient ventilation along the shell, based upon upward draught, the apertures being sufficiently wide and deep to reduce the presence of the horizontal web with regard to ventilation, and vertical fins passing through corresponding apertures are arranged at the outside of the shell.
A composition for providing a film on keratin fibres, the composition comprising: (a) a film-forming aminosilicone polymer, wherein the aminosilicone polymer comprises amino sidechains, and wherein the aminosilicone polymer has a weight average molecular weight of from 10,000 Dalton to 60,000 Dalton; (b) a silicone resin wherein the silicone resin is a MQ resin; (c) a thickening system comprising: o a deposition enhancer, wherein the deposition enhancer is a hydrophilic and non-ionic polymer, and wherein the deposition enhancer has a weight average molecular weight of from 700,000 Dalton to 3,000,000 Dalton; o a thickening polymer, wherein the thickening polymer has a weight average molecular weight of at least 10,000 Dalton, and wherein the thickening polymer is a cationic thickening polymer or is a non-ionic thickening polymer; and (d) a solvent. (a) a film-forming aminosilicone polymer, wherein the aminosilicone polymer comprises amino sidechains, and wherein the aminosilicone polymer has a weight average molecular weight of from 10,000 Dalton to 60,000 Dalton; (b) a silicone resin wherein the silicone resin is a MQ resin; (c) a thickening system comprising: o a deposition enhancer, wherein the deposition enhancer is a hydrophilic and non-ionic polymer, and wherein the deposition enhancer has a weight average molecular weight of from 700,000 Dalton to 3,000,000 Dalton; o a thickening polymer, wherein the thickening polymer has a weight average molecular weight of at least 10,000 Dalton, and wherein the thickening polymer is a cationic thickening polymer or is a non-ionic thickening polymer; and o a deposition enhancer, wherein the deposition enhancer is a hydrophilic and non-ionic polymer, and wherein the deposition enhancer has a weight average molecular weight of from 700,000 Dalton to 3,000,000 Dalton; o a thickening polymer, wherein the thickening polymer has a weight average molecular weight of at least 10,000 Dalton, and wherein the thickening polymer is a cationic thickening polymer or is a non-ionic thickening polymer; and (d) a solvent.
Process for feeding an agent for deaerating / defoaming to a process liquid in particular in a paper machine, characterized in that the agent is locally emulsified with the aid of at least one mixing element in water and the process liquid is added within less than 24 hours, preferably less than 12 hours after the emulsifying process, whereas the agent exhibits a melting point of at least 40 °C.
A method suitable for the removal of a coreless roll of a plastic film from a winding mandrel having an external surface, according to which: the mandrel is provided with an air distribution chamber axially extending between a back end and a fore end of the mandrel; in which said air distribution chamber can be connected to a source of pressurised air and is provided with a plurality of air outlet holes to create an air cushion between the external surface of the mandrel and internal turns of the coreless coil; and in which the coreless coil can be removed by sliding it towards the fore end of the mandrel characterised by the steps of: providing a tight piston sliding inside the air distribution chamber of the mandrel and, at the moment of removal of a coil; feeding pressurised air at the fore end of the air distribution chamber; advancing the coreless coil pushing it along the mandrel and simultaneously magnetically dragging the piston along the air distribution chamber, allowing the outflow of the pressurised air from the holes of the mandrel at a front part of the air distribution chamber between the tight piston and the fore end of the mandrel. the mandrel is provided with an air distribution chamber axially extending between a back end and a fore end of the mandrel; in which said air distribution chamber can be connected to a source of pressurised air and is provided with a plurality of air outlet holes to create an air cushion between the external surface of the mandrel and internal turns of the coreless coil; and in which the coreless coil can be removed by sliding it towards the fore end of the mandrel characterised by the steps of: providing a tight piston sliding inside the air distribution chamber of the mandrel and, at the moment of removal of a coil; feeding pressurised air at the fore end of the air distribution chamber; advancing the coreless coil pushing it along the mandrel and simultaneously magnetically dragging the piston along the air distribution chamber, allowing the outflow of the pressurised air from the holes of the mandrel at a front part of the air distribution chamber between the tight piston and the fore end of the mandrel. providing a tight piston sliding inside the air distribution chamber of the mandrel and, at the moment of removal of a coil; feeding pressurised air at the fore end of the air distribution chamber; advancing the coreless coil pushing it along the mandrel and simultaneously magnetically dragging the piston along the air distribution chamber, allowing the outflow of the pressurised air from the holes of the mandrel at a front part of the air distribution chamber between the tight piston and the fore end of the mandrel.
A guide extension catheter system, the system comprising: a proximal shaft having a rail member formed thereon; wherein the proximal shaft has an outer diameter; a removable push member releasably attached to the proximal shaft and coupled to the rail member; a distal sheath coupled to the proximal shaft; and wherein the distal sheath has an outer diameter greater than the outer diameter of the proximal shaft. a proximal shaft having a rail member formed thereon; wherein the proximal shaft has an outer diameter; a removable push member releasably attached to the proximal shaft and coupled to the rail member; a distal sheath coupled to the proximal shaft; and wherein the distal sheath has an outer diameter greater than the outer diameter of the proximal shaft.