A device impacting the cardiovascular system comprising: at least a pair of independent compression cuffs; a source of compressed air; gas-distribution units; a control and indication unit; an analyzer of ECG QRS-complex (29, 281, 2611); a unit (31, 311, 283, 2612) for registration of the blood flow in the extremity, wherein the compression cuffs comprising at least proximal (172, 175) and distal (171, 174) cuffs located around at least one extremity for creation of periodical compression and connected to a source of compressed air via the gas-distribution units; the control and indication unit is connected to the gas-distribution units, to the analyzer of ECG QRS- complex (29, 281, 2611) and to the unit (31, 311, 283, 2612) for registration of the blood flow in the extremity; the control and indication unit is capable of control of supplying pressure impulses into the said cuffs with a delay in relation to the R-peak of the current QRS-complex so that the impulse in a proximal cuff (172, 175) would start on coming of a blood pressure pulse wave from the heart to the mentioned proximal cuff, and the magnitude of delay of beginning of the pressure impulse in the said distal cuff (171, 174) in relation to the beginning of the pressure impulse in the said proximal cuff complies with the impulse wave travel time between the said cuffs; cut-off point for termination of the pressure impulses in the said proximal (172, 175) and distal (171, 174) cuffs is the same and occurs earlier than the beginning of the following QRS-complex; the unit (31, 311, 283, 2612) for registration of the blood flow in the extremity is placed distal relative to the compression cuffs locations the control and indication unit is capable of providing a correction of the pressure impulse parameters on the basis of said registration of the blood flow performed distal to the compression cuffs as follows: - delays between R-peaks of the current QRS-complex and the maximums of the blood pressure pulse waves in the absence and in the presence of said pressure impulse are determined; - a difference Δt is calculated according to the expression of: Δt=t b -t 0, wherein: t b, t 0 are the delays between R-peaks and the maximum values of the blood pressure pulse wave in the presence and in the absence of saud pressure impulse, respectively; and - the front of the pressure impulse t 1 in said proximal cuff is corrected according to the following expression: T 1 corr. = t 1 − Δt. at least a pair of independent compression cuffs; a source of compressed air; gas-distribution units; a control and indication unit; an analyzer of ECG QRS-complex (29, 281, 2611); a unit (31, 311, 283, 2612) for registration of the blood flow in the extremity, wherein the compression cuffs comprising at least proximal (172, 175) and distal (171, 174) cuffs located around at least one extremity for creation of periodical compression and connected to a source of compressed air via the gas-distribution units; the control and indication unit is connected to the gas-distribution units, to the analyzer of ECG QRS- complex (29, 281, 2611) and to the unit (31, 311, 283, 2612) for registration of the blood flow in the extremity; the control and indication unit is capable of control of supplying pressure impulses into the said cuffs with a delay in relation to the R-peak of the current QRS-complex so that the impulse in a proximal cuff (172, 175) would start on coming of a blood pressure pulse wave from the heart to the mentioned proximal cuff, and the magnitude of delay of beginning of the pressure impulse in the said distal cuff (171, 174) in relation to the beginning of the pressure impulse in the said proximal cuff complies with the impulse wave travel time between the said cuffs; cut-off point for termination of the pressure impulses in the said proximal (172, 175) and distal (171, 174) cuffs is the same and occurs earlier than the beginning of the following QRS-complex; the unit (31, 311, 283, 2612) for registration of the blood flow in the extremity is placed distal relative to the compression cuffs locations the control and indication unit is capable of providing a correction of the pressure impulse parameters on the basis of said registration of the blood flow performed distal to the compression cuffs as follows: - delays between R-peaks of the current QRS-complex and the maximums of the blood pressure pulse waves in the absence and in the presence of said pressure impulse are determined; - a difference Δt is calculated according to the expression of: Δt=t b -t 0, wherein: t b, t 0 are the delays between R-peaks and the maximum values of the blood pressure pulse wave in the presence and in the absence of saud pressure impulse, respectively; and - the front of the pressure impulse t 1 in said proximal cuff is corrected according to the following expression: T 1 corr. = t 1 − Δt. - delays between R-peaks of the current QRS-complex and the maximums of the blood pressure pulse waves in the absence and in the presence of said pressure impulse are determined; - a difference Δt is calculated according to the expression of: Δt=t b -t 0, wherein: t b, t 0 are the delays between R-peaks and the maximum values of the blood pressure pulse wave in the presence and in the absence of saud pressure impulse, respectively; and t b, t 0 are the delays between R-peaks and the maximum values of the blood pressure pulse wave in the presence and in the absence of saud pressure impulse, respectively; and - the front of the pressure impulse t 1 in said proximal cuff is corrected according to the following expression: T 1 corr. = t 1 − Δt.