mhurhangee/ep-ind-claims huggingface dataset:
Instrument for use with a bone anchoring device in spinal surgery, wherein the bone anchoring device includes a bone anchoring section and a receiving part having a bottom end adjacent to the bone anchoring section, a top end opposite to the bottom end and channel for receiving a rod, the channel having a bottom for supporting the rod, the instrument including a holding member (10, 10', 10") that is configured to hold the receiving part, wherein the holding member (10, 10', 10") comprises a first arm and a second arm that are movable relative to each other between an open position in which the receiving part is insertable between the first arm and the second arm into a closed position in which the receiving part is held between the first arm and the second arm, and a rod contacting member that is configured to contact the rod, wherein the rod contacting member is movable between the first arm and the second arm such that in the closed position of the first arm and second arm the rod contacting member can be advanced to move the rod towards the bottom of the channel; characterized in that the holding member comprises an engagement portion at each of the arms (12a, 12b) that is adapted to engage the receiving part at the bottom end. wherein the bone anchoring device includes a bone anchoring section and a receiving part having a bottom end adjacent to the bone anchoring section, a top end opposite to the bottom end and channel for receiving a rod, the channel having a bottom for supporting the rod, the instrument including a holding member (10, 10', 10") that is configured to hold the receiving part, wherein the holding member (10, 10', 10") comprises a first arm and a second arm that are movable relative to each other between an open position in which the receiving part is insertable between the first arm and the second arm into a closed position in which the receiving part is held between the first arm and the second arm, and a rod contacting member that is configured to contact the rod, wherein the rod contacting member is movable between the first arm and the second arm such that in the closed position of the first arm and second arm the rod contacting member can be advanced to move the rod towards the bottom of the channel; characterized in that the holding member comprises an engagement portion at each of the arms (12a, 12b) that is adapted to engage the receiving part at the bottom end.
Wheeled or tracked vehicle with a mounted machine gun which fires shots in rapid sequence and, provided on the vehicle, a running mechanism by means of which the vehicle body carrying the machine gun is made movable in relation to the wheel or chain mechanism, for which purpose a number of wheel or chain-wheel suspensions enabling compressive deflection are provided on the running mechanism, characterized in that just for firing, the compressive deflection behaviour of at least some of the wheel or chain-wheel suspensions can be modified in such a way that a deflection-induced movement of the machine gun is reduced, wherein each wheel or chain-wheel suspension that can be modified in its compressive deflection behaviour has a spring, the pre-tensioning of which can be varied to modify the compressive deflection behaviour.
An anti-FGF23 antibody for use in a method of treating X-linked hypophosphatemia, the method comprising administering to a human subject in need of such treatment an effective amount of the anti-FGF23 antibody, wherein the anti-FGF23 antibody is administered subcutaneously every two weeks, and wherein said anti-FGF23 antibody comprises the CDR sequences of SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, and SEQ ID NO: 6.
Floating pump comprising: flotation means on a liquid medium, an axial or semi-axial flow pump supported by the flotation means comprising an inlet and an outlet for the fluid to be pumped, such that in the working position, said axial or semi-axial flow pump is at least partially submerged in the fluid to be pumped between said inlet and said outlet, and wherein the axial or semi-axial flow pump comprises transmission means which in turn comprise a drive shaft, wherein said transmission means are arranged in fluid communication with said inlet and said outlet of the axial or semi-axial flow pump, enabling the establishment of a flow of fluid to be pumped between said inlet and said outlet in the working position, along a longitudinal axis of the axial or semi-axial flow pump coinciding with the drive shaft, such that in the working position the rotation of the drive shaft produces the flow of the fluid to be pumped from the inlet to the outlet, characterised in that in the working position of the floating pump, a first end of the drive shaft, located in proximity to the outlet of the axial or semi-axial flow pump, is in the submerged position, while a second end (6") of the drive shaft, opposite from the first end, is in the non-submerged position, such that the orientation of the drive shaft is inclined with respect to the surface of the liquid medium whereon the flotation means are located. flotation means on a liquid medium, an axial or semi-axial flow pump supported by the flotation means comprising an inlet and an outlet for the fluid to be pumped, such that in the working position, said axial or semi-axial flow pump is at least partially submerged in the fluid to be pumped between said inlet and said outlet, and wherein the axial or semi-axial flow pump comprises transmission means which in turn comprise a drive shaft, wherein said transmission means are arranged in fluid communication with said inlet and said outlet of the axial or semi-axial flow pump, enabling the establishment of a flow of fluid to be pumped between said inlet and said outlet in the working position, along a longitudinal axis of the axial or semi-axial flow pump coinciding with the drive shaft, such that in the working position the rotation of the drive shaft produces the flow of the fluid to be pumped from the inlet to the outlet, characterised in that in the working position of the floating pump, a first end of the drive shaft, located in proximity to the outlet of the axial or semi-axial flow pump, is in the submerged position, while a second end (6") of the drive shaft, opposite from the first end, is in the non-submerged position, such that the orientation of the drive shaft is inclined with respect to the surface of the liquid medium whereon the flotation means are located.
A process (1, 2) for processing feedstock containing cotton fibres and PET fibres, the process (1,2) comprising: i. heating a suspension of feedstock containing cotton fibres and PET fibres in water at a temperature above 180 °C to produce a mixture comprising char; ii. removing the water from the mixture comprising char; iii. adding a base to the mixture comprising char to produce a terephthalate salt in a liquid phase; iv. removing the char from the liquid phase to produce dried char; v. acidifying the liquid phase to produce terephthalic acid. i. heating a suspension of feedstock containing cotton fibres and PET fibres in water at a temperature above 180 °C to produce a mixture comprising char; ii. removing the water from the mixture comprising char; iii. adding a base to the mixture comprising char to produce a terephthalate salt in a liquid phase; iv. removing the char from the liquid phase to produce dried char; v. acidifying the liquid phase to produce terephthalic acid.
An in-vitro or ex-vivo method for producing an endogenous DNA-edited eukaryotic cell, comprising: introducing a CRISPR-Cas3 system into a eukaryotic cell, wherein the CRISPR-Cas3 system includes the following to: a Cas3 protein, a polynucleotide encoding the protein, or an expression vector containing the polynucleotide, a Cascade protein, a polynucleotide encoding the protein, or an expression vector containing the polynucleotide, and a pre-crRNA which targets the endogenous DNA, a polynucleotide encoding the pre-crRNA, or an expression vector containing the polynucleotide, wherein the method is not a process for modifying the germ line genetic identity of human beings. wherein the CRISPR-Cas3 system includes the following to: a Cas3 protein, a polynucleotide encoding the protein, or an expression vector containing the polynucleotide, a Cascade protein, a polynucleotide encoding the protein, or an expression vector containing the polynucleotide, and a pre-crRNA which targets the endogenous DNA, a polynucleotide encoding the pre-crRNA, or an expression vector containing the polynucleotide, a Cas3 protein, a polynucleotide encoding the protein, or an expression vector containing the polynucleotide, a Cascade protein, a polynucleotide encoding the protein, or an expression vector containing the polynucleotide, and a pre-crRNA which targets the endogenous DNA, a polynucleotide encoding the pre-crRNA, or an expression vector containing the polynucleotide, wherein the method is not a process for modifying the germ line genetic identity of human beings.
A method in an electronic device, the method comprising: performing stereo recording, to make a stereo audio signal having stereo sound effects, by obtaining a plurality of audio signals which are simultaneously outputted from a plurality of microphones; identifying a noise generation interval, wherein the noise is generated by driving of a driving body in the electronic device; replacing, during the noise generation interval, at least a portion of a first audio signal of the plurality of audio signals, which is recorded by a first microphone of the plurality of microphones that is influenced by the generated noise during the noise generation interval, with at least a portion of a second audio signal which is recorded by a second microphone of the plurality of microphones during the noise generation interval; and in response to the replacing, storing, in a memory of the electronic device, the first audio signal with the second audio signal as the stereo audio signal. performing stereo recording, to make a stereo audio signal having stereo sound effects, by obtaining a plurality of audio signals which are simultaneously outputted from a plurality of microphones; identifying a noise generation interval, wherein the noise is generated by driving of a driving body in the electronic device; replacing, during the noise generation interval, at least a portion of a first audio signal of the plurality of audio signals, which is recorded by a first microphone of the plurality of microphones that is influenced by the generated noise during the noise generation interval, with at least a portion of a second audio signal which is recorded by a second microphone of the plurality of microphones during the noise generation interval; and in response to the replacing, storing, in a memory of the electronic device, the first audio signal with the second audio signal as the stereo audio signal.
A heating method comprising: arranging a pair of electrodes (11, 12) on a workpiece (W1-W8) along a first direction, the pair of electrodes (11, 12) having a length extending across a first heating area of a workpiece (W1-W8) in the first direction; and moving at least one of the electrodes (11, 12) in the first heating area and along a second direction intersecting the first direction while applying electric current between the pair of electrodes (11, 12) to heat the first heating area by direct resistance heating, characterized by further comprising adjusting the electric current applied between the pair of electrodes (11, 12) while moving the at least one of the electrodes (11, 12) at a constant speed such that a heating temperature is adjusted for each segment (A1-An) into which the first heating area is divided so as to be side by side in the second direction. arranging a pair of electrodes (11, 12) on a workpiece (W1-W8) along a first direction, the pair of electrodes (11, 12) having a length extending across a first heating area of a workpiece (W1-W8) in the first direction; and moving at least one of the electrodes (11, 12) in the first heating area and along a second direction intersecting the first direction while applying electric current between the pair of electrodes (11, 12) to heat the first heating area by direct resistance heating, characterized by further comprising adjusting the electric current applied between the pair of electrodes (11, 12) while moving the at least one of the electrodes (11, 12) at a constant speed such that a heating temperature is adjusted for each segment (A1-An) into which the first heating area is divided so as to be side by side in the second direction.
A coin moving disk assembly for moving coins across a coin sorting member in a coin handling machine, the coin sorting member having at least one opening to receive coins of various denominations, the coin moving disk assembly comprising: an annular disk body having a groove portion positioned between an outer rim portion and a hub forming a central depression (300, the groove portion opening downwardly to receive a coin sensor assembly that projects upwardly into the groove portion, the outer rim portion having a cavity in a bottom surface; and a fin ring molded into the cavity in the bottom surface, the fin ring comprising planar fingers extending downward and substantially perpendicular to the bottom surface of the rim portion, the fingers being spaced around the rim portion of the fin ring, each of the fingers having a base disposed in the cavity in the bottom surface of the disk body and each of the fingers having a bottom edge that is substantially narrower in width than the base of each finger, the bottom edge also being narrower in width than a diameter of a smallest size of coin to be processed, so that each finger can press on a portion of the coin to tip an edge portion of a coin into an opening for receiving the coin. an annular disk body having a groove portion positioned between an outer rim portion and a hub forming a central depression (300, the groove portion opening downwardly to receive a coin sensor assembly that projects upwardly into the groove portion, the outer rim portion having a cavity in a bottom surface; and a fin ring molded into the cavity in the bottom surface, the fin ring comprising planar fingers extending downward and substantially perpendicular to the bottom surface of the rim portion, the fingers being spaced around the rim portion of the fin ring, each of the fingers having a base disposed in the cavity in the bottom surface of the disk body and each of the fingers having a bottom edge that is substantially narrower in width than the base of each finger, the bottom edge also being narrower in width than a diameter of a smallest size of coin to be processed, so that each finger can press on a portion of the coin to tip an edge portion of a coin into an opening for receiving the coin.
A method of manufacturing a steel cord or a single steel wire having excellent straightness quality for reinforcing tire, the method comprising: preparing a wire that has been drawn; heating the wire in a state in which tension is applied to the wire; cooling down the wire; and winding the wire on a winding portion having a diameter that is greater than a diameter of the wire, wherein a heating temperature in the heating of the wire is 200°C or less, and a cooling temperature in the cooling of the wire is 40°C or less, wherein the heating temperature, a heating time, and the tension applied to the wire during the heating of the wire satisfy condition A below, condition A: T + 13.67 In(t) + 0.27551 τ ≥ 425, wherein in condition A, T is an absolute temperature K of the heating temperature, t denotes the heating time s, and τ is the tension in Newton applied to the wire (or condition A: T + 13.67 ln(t) + 2.7 τ> 425 wherein in condition A, T is an absolute temperature K of the heating temperature, t denotes the heating time s, and τ is the tension (kgf) applied to the wire), wherein the method further comprising measuring straightness by fixing an end of the wire that has been wound on the winding portion for six months to one year at a point and pulling down the wire vertically to 400 mm, wherein, in the measuring of the straightness, a distance between a first axis that is perpendicular to the point and an opposite end of the wire is 30 mm or less. preparing a wire that has been drawn; heating the wire in a state in which tension is applied to the wire; cooling down the wire; and winding the wire on a winding portion having a diameter that is greater than a diameter of the wire, wherein a heating temperature in the heating of the wire is 200°C or less, and a cooling temperature in the cooling of the wire is 40°C or less, wherein the heating temperature, a heating time, and the tension applied to the wire during the heating of the wire satisfy condition A below, condition A: T + 13.67 In(t) + 0.27551 τ ≥ 425, wherein in condition A, T is an absolute temperature K of the heating temperature, t denotes the heating time s, and τ is the tension in Newton applied to the wire (or condition A: T + 13.67 ln(t) + 2.7 τ> 425 wherein in condition A, T is an absolute temperature K of the heating temperature, t denotes the heating time s, and τ is the tension (kgf) applied to the wire), wherein the method further comprising measuring straightness by fixing an end of the wire that has been wound on the winding portion for six months to one year at a point and pulling down the wire vertically to 400 mm, wherein, in the measuring of the straightness, a distance between a first axis that is perpendicular to the point and an opposite end of the wire is 30 mm or less.
A mounting kit for mounting a frame to a background, the mounting kit comprising: a dowel for insertion into a drilled hole in the background; and a fastening element for passing through a through hole in the frame and for insertion into the dowel in the drilled hole; wherein a first end portion of the fastening element is sized for insertion into the through hole and has a frame thread for retaining engagement with the frame; wherein a second end portion of the fastening element opposite the first end portion is sized for insertion into the dowel for securing the fastening element to the background by means of the dowel without the second end portion of the fastening element threading into the dowel, wherein the second end portion of the fastening element formed for insertion into the dowel is formed without threads. a dowel for insertion into a drilled hole in the background; and a fastening element for passing through a through hole in the frame and for insertion into the dowel in the drilled hole; wherein a first end portion of the fastening element is sized for insertion into the through hole and has a frame thread for retaining engagement with the frame; wherein a second end portion of the fastening element opposite the first end portion is sized for insertion into the dowel for securing the fastening element to the background by means of the dowel without the second end portion of the fastening element threading into the dowel, wherein the second end portion of the fastening element formed for insertion into the dowel is formed without threads.
An isolated antibody or antigen binding fragment thereof that binds canine Programmed Death Ligand 1 (canine PD-L1) with specificity comprising a set of three light chain complementary determining regions (CDRs): CDR light 1 (CDRL1), CDR light 2 (CDRL2), and CDR light 3 (CDRL3); with three heavy chain CDRs: CDR heavy 1 (CDRH1), CDR heavy 2 (CDRH2) and CDR heavy 3 (CDRH3) selected from the group consisting of: (a) wherein CDRH1 comprises the amino acid sequence of SEQ ID NO: 13; (b) wherein CDRH2 comprises the amino acid sequence of SEQ ID NO: 14; (c) wherein CDRH3 comprises the amino acid sequence of SEQ ID NO: 15; (d) wherein CDRL1 comprises the amino acid sequence of SEQ ID NO: 16; (e) wherein CDRL2 comprises the amino acid sequence of SEQ ID NO: 17; (f) wherein CDRL3 comprises the amino acid sequence of SEQ ID NO: 18; and (g) wherein CDRH1 comprises the amino acid sequence of SEQ ID NO: 19; (h) wherein CDRH2 comprises the amino acid sequence of SEQ ID NO: 20: (i) wherein CDRH3 comprises the amino acid sequence of SEQ ID NO: 21; (j) wherein CDRL1 comprises the amino acid sequence SEQ ID NO: 22; (k) wherein CDRL2 comprises the amino acid sequence of SEQ ID NO: 23; (l) wherein CDRL3 comprises the amino acid sequence of SEQ ID NO: 24; and wherein the antibody binds canine PD-L1 and block the binding of canine PD-L1 to canine Programmed Death 1 (PD-1). (a) wherein CDRH1 comprises the amino acid sequence of SEQ ID NO: 13; (b) wherein CDRH2 comprises the amino acid sequence of SEQ ID NO: 14; (c) wherein CDRH3 comprises the amino acid sequence of SEQ ID NO: 15; (d) wherein CDRL1 comprises the amino acid sequence of SEQ ID NO: 16; (e) wherein CDRL2 comprises the amino acid sequence of SEQ ID NO: 17; (f) wherein CDRL3 comprises the amino acid sequence of SEQ ID NO: 18; and (g) wherein CDRH1 comprises the amino acid sequence of SEQ ID NO: 19; (h) wherein CDRH2 comprises the amino acid sequence of SEQ ID NO: 20: (i) wherein CDRH3 comprises the amino acid sequence of SEQ ID NO: 21; (j) wherein CDRL1 comprises the amino acid sequence SEQ ID NO: 22; (k) wherein CDRL2 comprises the amino acid sequence of SEQ ID NO: 23; (l) wherein CDRL3 comprises the amino acid sequence of SEQ ID NO: 24; and wherein the antibody binds canine PD-L1 and block the binding of canine PD-L1 to canine Programmed Death 1 (PD-1).
A locking unit for a housing, in particular for a receptacle for objects, having at least two doors (6, 7) for locking respective housing openings (4, 5), in particular leading to storage compartments, wherein the locking unit has, for each of the doors (6, 7), in each case a locking element module (9, 10) with at least one locking body and a locking drive for actuating the locking body, characterized in that the locking drive for the locking element modules (9, 10) has a common drive element which is movable by an adjustment distance, and in a first adjustment position moves the locking body or bodies for merely one of the doors or merely a first group of two groups of doors of the doors (6, 7) into an unlocking position, and in a second adjustment position moves the locking bodies for all of the doors (6, 7) into an unlocking position.
Method for producing a moulded part with microstructures from impression material, comprising the following steps: Introducing the impression material into a container having an impression space, said impression space including at least one microstructured mould; centrifuging a container until said impression material has completely penetrated the structure of the mould; curing the impression material to give a moulded part with microstructures; removing said moulded part from the mould and the container, characterized by the production of a moulded part having first and second surfaces which are spaced from each other, with at least one microstructured surface which is produced by centrifugal force pressing the impression material into a first mould on said first surface, and by centrifugal force pressing a die element on said second surface onto the impression material layer.