A leadless cardiac pacing system (100, 1000), comprising: a first leadless pacing seed configured to deliver pacing therapy to a first location in a patient; and a second leadless pacing seed configured to deliver pacing therapy to a second location in a patient, the second leadless pacing seed comprising: an electrode (218, 219, 238, 239, 318, 319, 720) configured to deliver electrostimulation energy to the second location; a therapy circuit (214, 236, 314, 608, 710) configured to provide the electrostimulation energy to the electrode (218, 219, 238, 239, 318, 319, 720); a communications component (212, 224, 312, 616, 716) configured to send and receive communication signals; a power source (220, 320, 604, 704, 708, 1302) configured to provide electrical energy to the therapy circuit (214, 236, 314, 608, 710) and the communications component (212, 224, 312, 616, 716); and a power manager (216, 316, 618, 718) configured to detect an end-of-life condition associated with the second seed and, in response to detecting the end-of-life condition, to communicate a signal that causes the first seed to change from a first operational state to a second operational state, wherein when the first seed is in the second operational state, the first seed implements one or more operational parameters configured to adapt to a change in an output from the second seed resulting from the second seed entering the end-of-life condition. a first leadless pacing seed configured to deliver pacing therapy to a first location in a patient; and a second leadless pacing seed configured to deliver pacing therapy to a second location in a patient, the second leadless pacing seed comprising: an electrode (218, 219, 238, 239, 318, 319, 720) configured to deliver electrostimulation energy to the second location; a therapy circuit (214, 236, 314, 608, 710) configured to provide the electrostimulation energy to the electrode (218, 219, 238, 239, 318, 319, 720); a communications component (212, 224, 312, 616, 716) configured to send and receive communication signals; a power source (220, 320, 604, 704, 708, 1302) configured to provide electrical energy to the therapy circuit (214, 236, 314, 608, 710) and the communications component (212, 224, 312, 616, 716); and a power manager (216, 316, 618, 718) configured to detect an end-of-life condition associated with the second seed and, in response to detecting the end-of-life condition, to communicate a signal that causes the first seed to change from a first operational state to a second operational state, wherein when the first seed is in the second operational state, the first seed implements one or more operational parameters configured to adapt to a change in an output from the second seed resulting from the second seed entering the end-of-life condition. an electrode (218, 219, 238, 239, 318, 319, 720) configured to deliver electrostimulation energy to the second location; a therapy circuit (214, 236, 314, 608, 710) configured to provide the electrostimulation energy to the electrode (218, 219, 238, 239, 318, 319, 720); a communications component (212, 224, 312, 616, 716) configured to send and receive communication signals; a power source (220, 320, 604, 704, 708, 1302) configured to provide electrical energy to the therapy circuit (214, 236, 314, 608, 710) and the communications component (212, 224, 312, 616, 716); and a power manager (216, 316, 618, 718) configured to detect an end-of-life condition associated with the second seed and, in response to detecting the end-of-life condition, to communicate a signal that causes the first seed to change from a first operational state to a second operational state, wherein when the first seed is in the second operational state, the first seed implements one or more operational parameters configured to adapt to a change in an output from the second seed resulting from the second seed entering the end-of-life condition.