A system for adjusting neuromodulation parameters used by a neuromodulator (104; 204; 404; 604; 704;1304) operably connected to a plurality of electrodes (106; 206; 406; 606; 706) to modulate a neural target, comprising: a translation trigger detector configured to determine that a translation trigger has occurred; first parameter setting storage configured to store first parameter settings for use by the neuromodulator (104; 204; 404; 604; 704; 1304) to modulate the neural target; and a neuromodulation parameter translator operably connected to the translation trigger detector to: automatically translate the first parameter settings into a second parameter settings in response to determining the translation trigger has occurred; and replace the first parameter settings with the second parameter settings, or store the second parameter settings in a second parameter setting storage, wherein the automatically translating the first parameter settings into the second parameter settings includes either automatically translating from cathodic parameter settings to anodic parameter settings, or automatically translating from anodic parameter settings to cathodic parameter settings, wherein the neuromodulator (104; 204; 404; 604; 704;1304) is configured to use cathodic parameter settings for the neuromodulation parameters to deliver cathodic modulation to the neural target, and is configured to use anodic parameter settings for the neuromodulation parameters to deliver anodic modulation to the neural target, wherein the first parameter settings for the neuromodulation parameters include at least a polarity, an amplitude, and a fractionalization, wherein the neuromodulation parameter translator is configured to automatically translate the first parameter settings into the second parameter settings by changing the polarity for each active electrode in the plurality of electrodes, and wherein the neuromodulation parameter translator is configured to automatically translate the first parameter settings into the second parameter settings by multiplying the amplitude by a scale factor, wherein the scale factor is determined using a ratio between a first therapeutic range for the first parameter settings and a second therapeutic range for the second parameter settings, the first therapeutic range represents a range of amplitudes for the first parameter settings that extends from a therapeutic threshold to a side effect threshold, and the second therapeutic range represents a range of amplitudes for the second parameter settings that extends from a therapeutic threshold to a side effect threshold. a translation trigger detector configured to determine that a translation trigger has occurred; first parameter setting storage configured to store first parameter settings for use by the neuromodulator (104; 204; 404; 604; 704; 1304) to modulate the neural target; and a neuromodulation parameter translator operably connected to the translation trigger detector to: automatically translate the first parameter settings into a second parameter settings in response to determining the translation trigger has occurred; and replace the first parameter settings with the second parameter settings, or store the second parameter settings in a second parameter setting storage, automatically translate the first parameter settings into a second parameter settings in response to determining the translation trigger has occurred; and replace the first parameter settings with the second parameter settings, or store the second parameter settings in a second parameter setting storage, wherein the automatically translating the first parameter settings into the second parameter settings includes either automatically translating from cathodic parameter settings to anodic parameter settings, or automatically translating from anodic parameter settings to cathodic parameter settings, wherein the neuromodulator (104; 204; 404; 604; 704;1304) is configured to use cathodic parameter settings for the neuromodulation parameters to deliver cathodic modulation to the neural target, and is configured to use anodic parameter settings for the neuromodulation parameters to deliver anodic modulation to the neural target, wherein the first parameter settings for the neuromodulation parameters include at least a polarity, an amplitude, and a fractionalization, wherein the neuromodulation parameter translator is configured to automatically translate the first parameter settings into the second parameter settings by changing the polarity for each active electrode in the plurality of electrodes, and wherein the neuromodulation parameter translator is configured to automatically translate the first parameter settings into the second parameter settings by multiplying the amplitude by a scale factor, wherein the scale factor is determined using a ratio between a first therapeutic range for the first parameter settings and a second therapeutic range for the second parameter settings, the first therapeutic range represents a range of amplitudes for the first parameter settings that extends from a therapeutic threshold to a side effect threshold, and the second therapeutic range represents a range of amplitudes for the second parameter settings that extends from a therapeutic threshold to a side effect threshold.