A drug injection device using pulsed shock waves, the drug injection device comprising: a power unit configured to generate pulsed power; a pulsed shock wave generating unit configured to receive the pulsed power and generate the pulsed shock waves; an upper housing in which a liquid and the pulsed shock wave generating unit are disposed therein; a lower housing connected to the upper housing and having a drug disposed therein; a needle adaptor detachably coupled to the lower housing; a shock wave transmitting unit provided between the upper housing and the lower housing and configured to transmit the shock waves generated in the upper housing to the lower housing; and an injection unit disposed in the lower housing and configured to inject the drug, wherein the pulsed shock wave generating unit includes: a first shock wave generating electrode and a second shock wave generating electrode configured to receive the pulsed power and allow a current to flow; and a first insulating tube, wherein the first shock wave generating electrode is located in contact, or in non-contact within the first insulating tube characterized in that an end of the first shock wave generating electrode inside the first insulating tube that is opposite one end of the second shock wave generating electrode at the closest distance is not exposed outside the first insulating tube. a power unit configured to generate pulsed power; a pulsed shock wave generating unit configured to receive the pulsed power and generate the pulsed shock waves; an upper housing in which a liquid and the pulsed shock wave generating unit are disposed therein; a lower housing connected to the upper housing and having a drug disposed therein; a needle adaptor detachably coupled to the lower housing; a shock wave transmitting unit provided between the upper housing and the lower housing and configured to transmit the shock waves generated in the upper housing to the lower housing; and an injection unit disposed in the lower housing and configured to inject the drug, wherein the pulsed shock wave generating unit includes: a first shock wave generating electrode and a second shock wave generating electrode configured to receive the pulsed power and allow a current to flow; and a first insulating tube, wherein the first shock wave generating electrode is located in contact, or in non-contact within the first insulating tube characterized in that an end of the first shock wave generating electrode inside the first insulating tube that is opposite one end of the second shock wave generating electrode at the closest distance is not exposed outside the first insulating tube. a first shock wave generating electrode and a second shock wave generating electrode configured to receive the pulsed power and allow a current to flow; and a first insulating tube, wherein the first shock wave generating electrode is located in contact, or in non-contact within the first insulating tube characterized in that an end of the first shock wave generating electrode inside the first insulating tube that is opposite one end of the second shock wave generating electrode at the closest distance is not exposed outside the first insulating tube.