A porous polyethersulfone film having a surface layer (a), a surface layer (b), and a macrovoid layer sandwiched between the surface layer (a) and the surface layer (b), wherein the macrovoid layer has a partition wall bonded to the surface layers (a) and (b); and a plurality of macrovoids surrounded by the partition wall and the surface layers (a) and (b), the macrovoids having an average pore diameter in the film plane direction measured by a scanning electron microscope of 10 μm to 500 μm; wherein the partition wall of the macrovoid layer has a thickness of 0.1 μm to 50 μm; wherein each of the surface layers (a) and (b) has a thickness of 0.1 μm to 50 μm; wherein one of the surface layers (a) and (b) has a plurality of fine pores having an average pore diameter of more than 5 μm and not more than 200 μm, while the other has a plurality of fine pores having an average pore diameter of not less than 0.01 μm and not more than 200 μm; wherein each of the average pore diameters is obtained by calculating the average pore areas measured by a scanning electron microscope according to the following equation: average pore diameter = 2 ∗ (Sa/π) 0.5, wherein Sa denotes the average pore areas; wherein a surface opening ratio of one of the surface layers (a) and the surface layer (b) is not less than 15%, while the surface opening ratio of the other surface layer is not less than 10%, wherein each of the surface opening ratios is measured by a scanning electron microscope; wherein the fine pores in the surface layers (a) and (b) communicate with the macrovoid; and wherein the porous polyethersulfone film has a total film thickness of 5 μm to 500 μm, and a porosity of 50% to 95%. wherein the macrovoid layer has a partition wall bonded to the surface layers (a) and (b); and a plurality of macrovoids surrounded by the partition wall and the surface layers (a) and (b), the macrovoids having an average pore diameter in the film plane direction measured by a scanning electron microscope of 10 μm to 500 μm; wherein the partition wall of the macrovoid layer has a thickness of 0.1 μm to 50 μm; wherein each of the surface layers (a) and (b) has a thickness of 0.1 μm to 50 μm; wherein one of the surface layers (a) and (b) has a plurality of fine pores having an average pore diameter of more than 5 μm and not more than 200 μm, while the other has a plurality of fine pores having an average pore diameter of not less than 0.01 μm and not more than 200 μm; wherein each of the average pore diameters is obtained by calculating the average pore areas measured by a scanning electron microscope according to the following equation: average pore diameter = 2 ∗ (Sa/π) 0.5, wherein Sa denotes the average pore areas; wherein a surface opening ratio of one of the surface layers (a) and the surface layer (b) is not less than 15%, while the surface opening ratio of the other surface layer is not less than 10%, wherein each of the surface opening ratios is measured by a scanning electron microscope; wherein the fine pores in the surface layers (a) and (b) communicate with the macrovoid; and wherein the porous polyethersulfone film has a total film thickness of 5 μm to 500 μm, and a porosity of 50% to 95%.