mhurhangee/ep-ind-claims huggingface dataset:
A method for detecting an anti-drug antibody in an ADA:drug immune complex sample, comprising; a) pre-treating the sample at a high temperature to dissociate the ADA:drug immune complex in the sample and selectively denature the drug; b) isolating the ADA from the sample by a matrix; c) retrieving the ADA from the matrix using a buffer; and d) detecting the ADA in a cell-based assay or an in vitro assay; wherein the drug has a lower thermal stability than the ADA. a) pre-treating the sample at a high temperature to dissociate the ADA:drug immune complex in the sample and selectively denature the drug; b) isolating the ADA from the sample by a matrix; c) retrieving the ADA from the matrix using a buffer; and d) detecting the ADA in a cell-based assay or an in vitro assay;
A humidification chamber (104, 304, 602, 702) for a humidification apparatus, the humidification chamber (104, 304, 602, 702) being configured to hold a volume of liquid and comprising: at least one side wall; a top wall connected to the at least one side wall; a base surface connected to the at least one side wall; a cavity at least partially defined by the at least one side wall and the top wall; an inlet port (110, 310, 604, 704) defining a passage into the cavity of the humidification chamber (104, 304, 602, 702); an outlet port (112, 312, 606, 706) defining a passage out of the cavity of the humidification chamber (104, 304, 602, 702); and characterised by: a handle (608, 708) configured to allow a user to grasp the humidification chamber (104, 304, 602, 702) during installation and/or removal of the humidification chamber (104, 304, 602, 702) to/from the humidification apparatus, in use, wherein the handle (608, 708) extends partially around the humidification chamber (104, 304, 602, 702) and defines a gap between the handle and the chamber, and wherein the humidification chamber (104, 304, 602, 702) has a forward side in relation to its position in the humidification apparatus, and wherein the handle (608, 708) is configured to face in the forward direction. at least one side wall; a top wall connected to the at least one side wall; a base surface connected to the at least one side wall; a cavity at least partially defined by the at least one side wall and the top wall; an inlet port (110, 310, 604, 704) defining a passage into the cavity of the humidification chamber (104, 304, 602, 702); an outlet port (112, 312, 606, 706) defining a passage out of the cavity of the humidification chamber (104, 304, 602, 702); and characterised by: a handle (608, 708) configured to allow a user to grasp the humidification chamber (104, 304, 602, 702) during installation and/or removal of the humidification chamber (104, 304, 602, 702) to/from the humidification apparatus, in use, wherein the handle (608, 708) extends partially around the humidification chamber (104, 304, 602, 702) and defines a gap between the handle and the chamber, and wherein the humidification chamber (104, 304, 602, 702) has a forward side in relation to its position in the humidification apparatus, and wherein the handle (608, 708) is configured to face in the forward direction. a handle (608, 708) configured to allow a user to grasp the humidification chamber (104, 304, 602, 702) during installation and/or removal of the humidification chamber (104, 304, 602, 702) to/from the humidification apparatus, in use, wherein the handle (608, 708) extends partially around the humidification chamber (104, 304, 602, 702) and defines a gap between the handle and the chamber, and wherein the humidification chamber (104, 304, 602, 702) has a forward side in relation to its position in the humidification apparatus, and wherein the handle (608, 708) is configured to face in the forward direction.
A permanent magnet of the composition formula R p Fe q M r Cu t Co 100- p - q - r - t wherein R is at least one element selected from rare-earth elements, M is at least one of Zr, Ti and Hf, p is a number satisfying 10.8 ≤ p ≤ 12.5 atom%, q is a number satisfying 28 ≤ q ≤ 40 atom%, r is a number satisfying 0.88 ≤ r ≤ 4.5 atom%, and t is a number satisfying 3.5 ≤ t ≤ 13.5 atom%, the magnet comprising a sintered body including a plurality of crystal grains each having a Th 2 Zn 17 crystal phase, and a plurality of grain boundaries between the crystal grains, characterised in that, when an oxide phase of R is defined by a continuous region disposed in the sintered body and containing R and oxygen having a concentration of ≥ 85 atom%, the ratio of the number of oxide phases precipitates in the grain boundaries to the number of crystal grains is ≤ 1.1, in a region of a cross-section of the magnet analysed by SEM of not smaller than 200 μm × 400 μm and not larger than 300 μm × 500 μm. R is at least one element selected from rare-earth elements, M is at least one of Zr, Ti and Hf, p is a number satisfying 10.8 ≤ p ≤ 12.5 atom%, q is a number satisfying 28 ≤ q ≤ 40 atom%, r is a number satisfying 0.88 ≤ r ≤ 4.5 atom%, and t is a number satisfying 3.5 ≤ t ≤ 13.5 atom%, the magnet comprising a sintered body including a plurality of crystal grains each having a Th 2 Zn 17 crystal phase, and a plurality of grain boundaries between the crystal grains, characterised in that, when an oxide phase of R is defined by a continuous region disposed in the sintered body and containing R and oxygen having a concentration of ≥ 85 atom%, the ratio of the number of oxide phases precipitates in the grain boundaries to the number of crystal grains is ≤ 1.1, in a region of a cross-section of the magnet analysed by SEM of not smaller than 200 μm × 400 μm and not larger than 300 μm × 500 μm.
A method for optimising a short-term stability of a clock pulse of a clock source synchronised with a first longterm stable reference-clock source with the following method steps: Transmission of clock-cycle numbers of a first reference clock of the first reference-clock source (2 1, 2 2, 2 3, 2 4) to the clock source between an initialisation time and, in each case, several times, within a data-packet orientated network, Adjustment of the clock pulse of the clock source by controlling a difference between clock-cycle numbers of the first reference clock received in the clock source and clock-cycle numbers of the first reference clock between the initialisation time and the respective reception times of the clock-cycle numbers of the first reference clock, wherein the received clock-cycle numbers of the first reference clock are matched with a frequency of a frequency oscillator integrated in a phase-locked loop for the controlling, Transmission of clock-cycle numbers of a second reference clock of the data packet which receives the clock-cycle number from at least one second, free-running reference-clock source (11 1, 11 2) at individual times to the clock source, and Limiting of the difference between the clock pulse of the clock source and each second reference clock to a first adjustable threshold value. Transmission of clock-cycle numbers of a first reference clock of the first reference-clock source (2 1, 2 2, 2 3, 2 4) to the clock source between an initialisation time and, in each case, several times, within a data-packet orientated network, Adjustment of the clock pulse of the clock source by controlling a difference between clock-cycle numbers of the first reference clock received in the clock source and clock-cycle numbers of the first reference clock between the initialisation time and the respective reception times of the clock-cycle numbers of the first reference clock, wherein the received clock-cycle numbers of the first reference clock are matched with a frequency of a frequency oscillator integrated in a phase-locked loop for the controlling, Transmission of clock-cycle numbers of a second reference clock of the data packet which receives the clock-cycle number from at least one second, free-running reference-clock source (11 1, 11 2) at individual times to the clock source, and Limiting of the difference between the clock pulse of the clock source and each second reference clock to a first adjustable threshold value.
A heat-resistant austenitic stainless steel having excellent cyclic oxidation resistance, consisting of C: 0.05 to 0.2% (mass% for chemical composition here and hereinafter), Si: 0.1 to 1%, Mn: 0.1 to 2.5%, Cu: 1 to 4%, Ni: 7 to 12%, Cr: 16 to 20%, Nb: 0.1 to 0.6%, Zr: 0.05 to 0.4%, Ce: 0.005 to 0.1%, Ti: 0.1 to 0.6%, B: 0.0005 to 0.005%, N: 0.001 to 0.15%, S: 0.005% or less (not including 0%), P: 0.05% or less (not including 0%), optionally Mo: 3% or less, optionally W: 5% or less, optionally Ca: 0.005% or less, and optionally Mg: 0.005% or less respectively, with the balance of iron and unavoidable impurities.
A dentifrice composition comprising by weight a. 35-45% of water; b. 0.7% to 1.2% of a component for enhancing flavor delivery and rheological profile, wherein the component comprises a blend of: b1. 80% to 90% of a microcrystalline cellulose; and b2. 10% to 20% of sodium carboxymethylcellulose; wherein the weight percentage of b1. and b2. is based on the total weight of component; and c. an effective amount of a silica abrasive, wherein the silica abrasive component comprises 15-25% of the composition, wherein the composition is obtained or obtainable by premixing the blend of microcrystalline cellulose and sodium carboxymethyl cellulose in water prior to combination with the other ingredients. a. 35-45% of water; b. 0.7% to 1.2% of a component for enhancing flavor delivery and rheological profile, wherein the component comprises a blend of: b1. 80% to 90% of a microcrystalline cellulose; and b2. 10% to 20% of sodium carboxymethylcellulose; wherein the weight percentage of b1. and b2. is based on the total weight of component; and b1. 80% to 90% of a microcrystalline cellulose; and b2. 10% to 20% of sodium carboxymethylcellulose; c. an effective amount of a silica abrasive, wherein the silica abrasive component comprises 15-25% of the composition,
A cell line comprising: a. an ARPE-19 cell genetically engineered to produce a therapeutically effective amount of one or more anti-angiogenic antibody-scaffold or anti-angiogenic molecules, wherein the one or more anti-angiogenic antibody-scaffold or anti-angiogenic molecules are introduced into the ARPE-19 cell by at least one transfection, wherein the transfection comprises one transfection, two transfections, or three transfections and wherein the one or more anti-angiogenic antibody-scaffold or anti-angiogenic molecules is encoded by a nucleic acid sequence selected from the group consisting of SEQ ID NO: 1_or has an amino acid sequence selected from the group consisting of SEQ ID NO:2; or b. an ARPE-19 cell genetically engineered to produce a therapeutically effective amount of one or more anti-angiogenic antibody-scaffolds or anti-angiogenic molecules, wherein the therapeutically effective amount is at least 10,000 ng/day/10 6 cells and wherein the one or more anti-angiogenic scaffolds or anti-angiogenic molecules is encoded by a nucleic acid sequence selected from the group consisting of SEQ ID NO: 1, or has an amino acid sequence selected from the group consisting of SEQ ID NO: 2. a. an ARPE-19 cell genetically engineered to produce a therapeutically effective amount of one or more anti-angiogenic antibody-scaffold or anti-angiogenic molecules, wherein the one or more anti-angiogenic antibody-scaffold or anti-angiogenic molecules are introduced into the ARPE-19 cell by at least one transfection, wherein the transfection comprises one transfection, two transfections, or three transfections and wherein the one or more anti-angiogenic antibody-scaffold or anti-angiogenic molecules is encoded by a nucleic acid sequence selected from the group consisting of SEQ ID NO: 1_or has an amino acid sequence selected from the group consisting of SEQ ID NO:2; or b. an ARPE-19 cell genetically engineered to produce a therapeutically effective amount of one or more anti-angiogenic antibody-scaffolds or anti-angiogenic molecules, wherein the therapeutically effective amount is at least 10,000 ng/day/10 6 cells and wherein the one or more anti-angiogenic scaffolds or anti-angiogenic molecules is encoded by a nucleic acid sequence selected from the group consisting of SEQ ID NO: 1, or has an amino acid sequence selected from the group consisting of SEQ ID NO: 2.
A piston for a gaseous fuel internal combustion engine, comprising: a piston skirt extending circumferentially about a central axis; a piston top face extending in a plane perpendicular to the central axis and including an inner edge circumferentially extending about the central axis; and a pot-shaped piston bowl including a bowl side face extending circumferentially about the central axis, the piston bowl and the piston top face being connected via the inner edge of the piston top face, wherein the bowl side face includes a plurality of recesses and protrusions arranged alternately to each other in a circumferential direction about the central axis, the protrusions extending in a direction to the central axis, and the recesses and the protrusions are configured so that the inner edge has a pinwheel shape, characterized in that the recesses consist of a helical recess that helically extends about the central axis; and/or the protrusions consist of a helical protrusion that helically extends about the central axis. a piston skirt extending circumferentially about a central axis; a piston top face extending in a plane perpendicular to the central axis and including an inner edge circumferentially extending about the central axis; and a pot-shaped piston bowl including a bowl side face extending circumferentially about the central axis, the piston bowl and the piston top face being connected via the inner edge of the piston top face, wherein the bowl side face includes a plurality of recesses and protrusions arranged alternately to each other in a circumferential direction about the central axis, the protrusions extending in a direction to the central axis, and the recesses and the protrusions are configured so that the inner edge has a pinwheel shape, characterized in that the recesses consist of a helical recess that helically extends about the central axis; and/or the protrusions consist of a helical protrusion that helically extends about the central axis.
Method for determining the temperature of the conveyed medium of a circulation pump, in particular a heating circulation pump, with an integral electric drive unit, wherein the temperature of the conveying medium is determined or calculated on the basis of the winding temperature of the electric pump unit and the applied winding current, wherein the conveying medium temperature is determined from the applied winding current and the measured winding temperature using an observer, characterized in that the observer uses a pump model to simulate the pump operation, which outputs a simulated winding temperature depending on an estimated conveying medium temperature and the winding current, wherein the observer determines a correction value for correction of the estimated conveying medium temperature from the difference of the simulated and measured winding temperatures, which is fed back to the pump model.
A method for classifying white blood cells (WBCs) in a biological sample on a substrate, the method comprising: acquiring, by an image acquisition device, one or more images of the substrate; extracting a plurality of features of the white blood cells in the biological sample from the one or more images; and performing a plurality of classifications for each white blood cell, each classification based on a corresponding feature vector composed of one or more of the extracted features of the respective white blood cell, each classification including either maintaining a previous classification of the white blood cell or changing a previous classification of the white blood cell, wherein at least one of the classifications includes a linear discriminant analysis classification and at least one of the classifications includes a Bayesian classification. acquiring, by an image acquisition device, one or more images of the substrate; extracting a plurality of features of the white blood cells in the biological sample from the one or more images; and performing a plurality of classifications for each white blood cell, each classification based on a corresponding feature vector composed of one or more of the extracted features of the respective white blood cell, each classification including either maintaining a previous classification of the white blood cell or changing a previous classification of the white blood cell, wherein at least one of the classifications includes a linear discriminant analysis classification and at least one of the classifications includes a Bayesian classification.
A method of distributing a plurality of multicast streams to a plurality of hosts on a link-aggregation-group between a first network element and a second network element, wherein the plurality of hosts are coupled to the second network element and the link-aggregation-group includes a plurality of links coupling the second network element and the first network element, the method comprising the steps of: receiving, with the first network element, a multicast request that requests to join one of the plurality of multicast streams from one of the plurality of hosts, wherein the multicast request includes a type code that indicates a type of the requested multicast stream; determining a bandwidth amount for the one of the plurality of multicast streams using the type code contained in the requested multicast request; allocating the bandwidth amount on one of the plurality of links; and in response to a successful allocation of the bandwidth amount, updating a forwarding table to indicate that the requested plurality of multicast streams is to be forwarded on the one of the plurality of links. receiving, with the first network element, a multicast request that requests to join one of the plurality of multicast streams from one of the plurality of hosts, wherein the multicast request includes a type code that indicates a type of the requested multicast stream; determining a bandwidth amount for the one of the plurality of multicast streams using the type code contained in the requested multicast request; allocating the bandwidth amount on one of the plurality of links; and in response to a successful allocation of the bandwidth amount, updating a forwarding table to indicate that the requested plurality of multicast streams is to be forwarded on the one of the plurality of links.
A wireless information communication terminal comprising a component for outputting a first piece of information, a first receiver of the ultra-wide band type capable of receiving a first signal containing first data along a determined first wireless communication channel of the ultra-wide band type, a control unit for generating the first piece of information to be sent to the outputting component depending on the first data received by the first receiver, the terminal further comprising at least one second emitter capable of emitting a second signal along a determined second wireless communication channel of the ultra-wide band type, the control unit being configured to bring about the emission of the second signal by the second emitter in response to the first receiver receiving the first signal, characterized in that the terminal further comprises a third receiver for receiving along a third wireless communication channel a third trigger signal, the control unit being configured to activate, in response to the third receiver receiving the third trigger signal, for a predetermined period of time the first receiver of the ultra-wide band type so as to make said first receiver receive the first signal containing first data along the determined first wireless communication channel of the ultra-wide band type, the third communication channel being different from the first communication channel at least in that the third receiver has, over the same activation period, lower energy consumption than that of the first receiver.
A polypeptide comprising a first immunogenic amino acid sequence and a second immunogenic amino acid sequence, wherein the first immunogenic amino acid sequence is SEQ ID NO 23.
A hydraulic binder particularly intended to make up a decorative concrete/mortar, characterised in that it is made up of a Portland cement blend, with at least 50% of at least one type of industrial silicate glass, and particularly container glass or recycled flat glass, ground to an average grain size comprised between 10 μ and 35 μ.
Method for distilling, in particular ethanol from a mash, in which a feed is fed into a first distillation column and a distillate from the first distillation column is fed into a second distillation column, characterised in that the feed is purified by means of a first membrane separation process, a permeate from the first membrane separation process being fed into the second distillation column and a retentate from the first membrane separation process being fed into the first distillation column and/or the distillate from the second distillation column being purified by means of a second membrane separation process in order to obtain a final product.
Transport device for transporting a winglet in a cargo hold of an aircraft, comprising - a base element comprising at least one support element, wherein - the support element is configured to support the winglet with respect to the base element in a predefined support position, wherein - the transport device comprises a cargo element, which is suitable to form a support of the transport device at a floor structure of the cargo hold, wherein - the base element is rotatably mounted with respect to the cargo element via a rotary joint, and - the cargo element comprises a fastening means for fixing the cargo element within a cargo hold of an aircraft. - a base element comprising at least one support element, - the support element is configured to support the winglet with respect to the base element in a predefined support position, wherein - the transport device comprises a cargo element, which is suitable to form a support of the transport device at a floor structure of the cargo hold, wherein - the base element is rotatably mounted with respect to the cargo element via a rotary joint, and - the cargo element comprises a fastening means for fixing the cargo element within a cargo hold of an aircraft.
A butyl rubber latex composition comprising a butyl rubber ionomer made from a halogenated butyl rubber reacted with a nitrogen or phosphorous based nucleophile emulsified in water, whereby the butyl rubber is derived from at least one isoolefin monomer and at least one multiolefin.
An air supply arrangement for supply of compressed air to an air jet nozzle in an air jet weaving machine, the air supply arrangement comprising a compressed air supply unit adapted to supply compressed air to the air jet nozzle, the air supply arrangement further comprising a valve interconnected between the air supply unit and the air jet nozzle, characterized in that the valve comprises a core that can be magnetized using a coil fed with an excitation current, the valve further comprising a valve member being made at least partly of a magnetic material, said valve member being formed by at least three stacked plates (51, 91), said plates being at least partially displaceable in relation to each other in at least one direction and having a thickness of 0.02 - 0.5 mm, the valve member being located in a space interconnecting an inlet and outlet of the valve, wherein the valve member can move in the space between two positions; a first position when there is no excitation current in the coil, and a second position where there is an excitation current in the coil and where the valve member is attracted by the core and wherein in one of the two positions the valve member is forced to close and in the other position to open a compressed air flow passage formed in the space between the inlet and outlet of the valve and leading further to the air-jet nozzle.