A biosecurity system comprising: (a) a passenger information apparatus, which correlates a sample taken from a passenger to a diagnostic test cartridge and to an identity token of the passenger, the identity token being uniquely assigned to each passenger, and which is in communication with (i) a first database containing information of geographic locations and infectious diseases prevalent to the geographic locations, and (ii) a second database containing information of geographic locations in passengers' travel itinerary, wherein the apparatus generates a request for diagnostic testing for a passenger, when an overlap is detected between the geographic locations of the first database and the geographic locations in the passenger's travel itinerary in the second database, for a pathogen or pathogens causing the infectious disease(s) prevalent to the overlapping geographic location(s),; (b) at least one diagnostic test cartridge, which (i) comprises a sample chamber for receiving the sample or an extract thereof, and (ii) contains at least one diagnostic test reagent for detecting the presence of the pathogen or pathogens; (c) at least one diagnostic testing instrument, which performs a diagnostic test on the sample in the at least one diagnostic test cartridge to generate a test result that reports the presence or absence of the pathogen or pathogens in the sample; and (d) a communication means for transmitting the test result to the passenger information apparatus, wherein positive and negative test results are correlated with individual passengers via their identity tokens, wherein the passenger information apparatus is configured to generate a set of instructions to be transmitted to a reader or scanner of the passenger identity tokens, and wherein the instructions from the passenger information apparatus then direct the reader or scanner to produce an alarm signal once it reads or scans a token corresponding to a passenger whose sample has been tested positive for a biological agent, wherein the sample is preferably blood, saliva, sweat, tear, a swab of oral or nasal mucosa, or a swab of skin or clothing, wherein the at least one diagnostic test cartridge preferably further comprises a reagent chamber for storing the at least one diagnostic test reagent, and a reaction chamber for conducting the diagnostic testing, wherein the sample chamber, the reagent chamber, and the reaction chamber are in selective fluidic communication with each other, or wherein the at least one diagnostic testing instrument preferably does not remove any substance from the at least one diagnostic test cartridge. (a) a passenger information apparatus, which correlates a sample taken from a passenger to a diagnostic test cartridge and to an identity token of the passenger, the identity token being uniquely assigned to each passenger, and which is in communication with (i) a first database containing information of geographic locations and infectious diseases prevalent to the geographic locations, and (ii) a second database containing information of geographic locations in passengers' travel itinerary, wherein the apparatus generates a request for diagnostic testing for a passenger, when an overlap is detected between the geographic locations of the first database and the geographic locations in the passenger's travel itinerary in the second database, for a pathogen or pathogens causing the infectious disease(s) prevalent to the overlapping geographic location(s),; (b) at least one diagnostic test cartridge, which (i) comprises a sample chamber for receiving the sample or an extract thereof, and (ii) contains at least one diagnostic test reagent for detecting the presence of the pathogen or pathogens; (c) at least one diagnostic testing instrument, which performs a diagnostic test on the sample in the at least one diagnostic test cartridge to generate a test result that reports the presence or absence of the pathogen or pathogens in the sample; and (d) a communication means for transmitting the test result to the passenger information apparatus, wherein positive and negative test results are correlated with individual passengers via their identity tokens, wherein the passenger information apparatus is configured to generate a set of instructions to be transmitted to a reader or scanner of the passenger identity tokens, and wherein the instructions from the passenger information apparatus then direct the reader or scanner to produce an alarm signal once it reads or scans a token corresponding to a passenger whose sample has been tested positive for a biological agent, wherein the sample is preferably blood, saliva, sweat, tear, a swab of oral or nasal mucosa, or a swab of skin or clothing, wherein the at least one diagnostic test cartridge preferably further comprises a reagent chamber for storing the at least one diagnostic test reagent, and a reaction chamber for conducting the diagnostic testing, wherein the sample chamber, the reagent chamber, and the reaction chamber are in selective fluidic communication with each other, or wherein the at least one diagnostic testing instrument preferably does not remove any substance from the at least one diagnostic test cartridge.