A wipe comprising: a substrate comprising a sponge, a woven fabric, or a nonwoven fabric, wherein the substrate is flexible; and a cationic coating disposed on a surface of the substrate, distributed throughout at least a portion of the substrate, or both, the cationic coating comprising a guanidinyl-containing polymer that is crosslinked on the substrate, covalently bonded to the substrate, or both; and a liquid comprising water, a water-miscible organic solvent, or a mixture thereof, wherein the liquid is present in an amount of 0.5 to 10 times of the weight of the dry wipe; wherein the guanidinyl-containing polymer is of the Formula: wherein: R 1 is hydrogen, C 1 -C 12 (hetero)alkyl, a C 5 -C 12 (hetero)aryl, or a residue of the polymer chain; R 2 is a covalent bond, a C 2 to C 12 (hetero)alkylene, or a C 5 -C 12 (hetero)arylene; R 3 is hydrogen, C 1 -C 12 (hetero)alkyl, C 5 -C 12 (hetero)aryl, or a residue of the polymer chain when n is 0; each R 4 is independently hydrogen, C 1 -C 12 (hetero)alkyl, C 5 -C 12 (hetero)aryl; R 5 is hydrogen, C 1 -C 12 (hetero)alkyl, or C 5 -C 12 (hetero)aryl, or -N(R 4) 2; n is 0 or 1; m is 1 or 2; and x is an integer equal to at least 1, and wherein the wipe, when contacted in the presence of a liquid with an area of a microorganism-contaminated surface, removes at least 99 percent of the microorganisms are removed from the area, and wherein the wipe, when contacted in the presence of the liquid with the area of the microorganism-contaminated surface and then contacted with a second surface, transfers no more than 0.2 percent of the microorganisms from the wipe to the second surface. a substrate comprising a sponge, a woven fabric, or a nonwoven fabric, wherein the substrate is flexible; and a cationic coating disposed on a surface of the substrate, distributed throughout at least a portion of the substrate, or both, the cationic coating comprising a guanidinyl-containing polymer that is crosslinked on the substrate, covalently bonded to the substrate, or both; and a liquid comprising water, a water-miscible organic solvent, or a mixture thereof, wherein the liquid is present in an amount of 0.5 to 10 times of the weight of the dry wipe; wherein the guanidinyl-containing polymer is of the Formula: wherein: R 1 is hydrogen, C 1 -C 12 (hetero)alkyl, a C 5 -C 12 (hetero)aryl, or a residue of the polymer chain; R 2 is a covalent bond, a C 2 to C 12 (hetero)alkylene, or a C 5 -C 12 (hetero)arylene; R 3 is hydrogen, C 1 -C 12 (hetero)alkyl, C 5 -C 12 (hetero)aryl, or a residue of the polymer chain when n is 0; each R 4 is independently hydrogen, C 1 -C 12 (hetero)alkyl, C 5 -C 12 (hetero)aryl; R 5 is hydrogen, C 1 -C 12 (hetero)alkyl, or C 5 -C 12 (hetero)aryl, or -N(R 4) 2; n is 0 or 1; m is 1 or 2; and x is an integer equal to at least 1, and R 1 is hydrogen, C 1 -C 12 (hetero)alkyl, a C 5 -C 12 (hetero)aryl, or a residue of the polymer chain; R 2 is a covalent bond, a C 2 to C 12 (hetero)alkylene, or a C 5 -C 12 (hetero)arylene; R 3 is hydrogen, C 1 -C 12 (hetero)alkyl, C 5 -C 12 (hetero)aryl, or a residue of the polymer chain when n is 0; each R 4 is independently hydrogen, C 1 -C 12 (hetero)alkyl, C 5 -C 12 (hetero)aryl; R 5 is hydrogen, C 1 -C 12 (hetero)alkyl, or C 5 -C 12 (hetero)aryl, or -N(R 4) 2; n is 0 or 1; m is 1 or 2; and x is an integer equal to at least 1, and wherein the wipe, when contacted in the presence of a liquid with an area of a microorganism-contaminated surface, removes at least 99 percent of the microorganisms are removed from the area, and wherein the wipe, when contacted in the presence of the liquid with the area of the microorganism-contaminated surface and then contacted with a second surface, transfers no more than 0.2 percent of the microorganisms from the wipe to the second surface.