mhurhangee/ep-ind-claims huggingface dataset:
Process of producing a multilayer lignocellulosic composite comprising one or more lignocellulosic composite layers or a single-layer lignocellulosic composite, comprising at least the following steps: a) providing or preparing a mixture at least comprising - lignocellulosic particles and - a binder comprising as components for hardening the binder via esterification at least ▪ one, two or more polymers comprising multiple hydroxy groups and, for crosslinking said polymers, ▪ one, two or more polymer or monomer compounds having two or more carboxyl groups; b) compacting the mixture; and c) applying a high-frequency electrical field to the mixture during and/or after compacting, so that the binder hardens via esterification of said components and binds the lignocellulosic particles, so that a single-layer lignocellulosic composite or a layer of a multilayer lignocellulosic composite results. a) providing or preparing a mixture at least comprising - lignocellulosic particles and - a binder comprising as components for hardening the binder via esterification at least ▪ one, two or more polymers comprising multiple hydroxy groups and, for crosslinking said polymers, ▪ one, two or more polymer or monomer compounds having two or more carboxyl groups; - lignocellulosic particles and - a binder comprising as components for hardening the binder via esterification at least ▪ one, two or more polymers comprising multiple hydroxy groups and, for crosslinking said polymers, ▪ one, two or more polymer or monomer compounds having two or more carboxyl groups; ▪ one, two or more polymers comprising multiple hydroxy groups and, for crosslinking said polymers, ▪ one, two or more polymer or monomer compounds having two or more carboxyl groups; b) compacting the mixture; and c) applying a high-frequency electrical field to the mixture during and/or after compacting, so that the binder hardens via esterification of said components and binds the lignocellulosic particles, so that a single-layer lignocellulosic composite or a layer of a multilayer lignocellulosic composite results.
A drug eluting device for use as part of a treatment for one or more of chronic inflammatory injury, metaplasia, dysplasia or cancer of an epithelial tissue, which device comprises drug release means including: (a) ponatinib; and (b) an anti-PESC agent selected from the group consisting of which device when deployed in a patient positions the drug release means proximal to the surface of the diseased tissue and releases ponatinib and the anti-PESC agent in an amount sufficient to achieve a therapeutically effective exposure of the diseased tissue to the ponatinib and the anti-PESC agent. (a) ponatinib; and (b) an anti-PESC agent selected from the group consisting of which device when deployed in a patient positions the drug release means proximal to the surface of the diseased tissue and releases ponatinib and the anti-PESC agent in an amount sufficient to achieve a therapeutically effective exposure of the diseased tissue to the ponatinib and the anti-PESC agent.
An internal combustion engine having a cylinder head, to which an exhaust manifold is fastened by means of fastening elements, wherein the fastening elements comprise at least one threaded bolt retained on the cylinder head and passing through a passage opening in the exhaust manifold and at least one nut screwed onto the threaded bolt by means of an internal thread section, by means of which nut force is applied to the exhaust manifold in the direction of the cylinder head, wherein the nut is directly or indirectly supported axially on the cylinder head and/or on a seal lying on the cylinder head by means of a first supporting surface and is directly or indirectly supported axially on the exhaust manifold by means of a second supporting surface, wherein the first supporting surface is formed by an end face of an axial supporting section passing through the passage opening, the inner circumferential surface of said supporting section being located at a radial distance from the threaded bolt, wherein the supporting section is formed by the nut or an optional sleeve, characterized in that the fastening elements comprise braking torque means for increasing the loosening torque, and the second supporting surface is formed on a radially protruding spring section of the nut that is elastically preloaded in the axial direction.
An ink-jet white ink of active energy ray-curable type, comprising titanium oxide, a basic dispersant as a pigment dispersant, and a polymerizable compound, wherein the content of the titanium oxide is from 15 to 30% by weight with reference to the total weight of the ink, wherein the weight average particle diameter of the titanium oxide is 180 to 250 nm, wherein the titanium oxide is titanium oxide whose surface is treated with at least silica, and wherein the content of the pigment dispersant is from 3 to 8 parts by weight with reference to 100 parts by weight of titanium oxide. wherein the content of the titanium oxide is from 15 to 30% by weight with reference to the total weight of the ink, wherein the weight average particle diameter of the titanium oxide is 180 to 250 nm, wherein the titanium oxide is titanium oxide whose surface is treated with at least silica, and wherein the content of the pigment dispersant is from 3 to 8 parts by weight with reference to 100 parts by weight of titanium oxide.
A method for determining the molecular weight distribution of glatiramer acetate, which method comprises subjecting glatiramer acetate to size exclusion chromatography, wherein the chromatographic column is calibrated by using a broad molecular weight distribution standard which consists of a mixture of polypeptides (b) having a known absolute molecular weight distribution, each of which polypeptide comprises L-glutamic acid, L-alanine, L-tyrosine and L-lysine wherein, in the mixture of polypeptides (b), the molar fraction range of L-glutamic acid is 0.129-0.153, of L-alanine is 0.392-0.462, of L-tyrosine is 0.086-0.100, and of L-lysine is 0.300-0.374 and wherein the mixture of polypeptides (b) has a cumulative molecular weight distribution as reported in the following table: Area Percent Molecular Weight 1 25000 5 18800 10 15800 20 12500 30 10500 40 8950 50 7760 60 6690 70 5750 80 4860 90 3860 95 3170 99 1990
Machine for cooling and truing cast components made from cast material, consisting of a construction for holding cast components and a holder for supplying cooling liquids, characterized in that the machine has means (12, 22) for holding the cast component by means of pressure cylinders, and in that truing pressure cylinders with truing rams are installed which press the cast component against pads.
A high-pressure fuel supply pump, comprising a metal pump body forming a pressurizing chamber, wherein the pump body is made of a steel material containing 12% to 18% of Cr and 3% to 7% of Ni, wherein the pump body is formed such that an outer peripheral portion has a substantially cylindrical shape, characterized in that the pump body and flange portions to be attached to an engine are integrally molded by forging with the same member, the flange portions are formed by spaces, recessed inward with respect to an outermost peripheral end portion of the outer peripheral portion, and the pump body has a forging surface on a part of its outer peripheral surface. wherein the pump body is made of a steel material containing 12% to 18% of Cr and 3% to 7% of Ni, wherein the pump body is formed such that an outer peripheral portion has a substantially cylindrical shape, characterized in that the pump body and flange portions to be attached to an engine are integrally molded by forging with the same member, the flange portions are formed by spaces, recessed inward with respect to an outermost peripheral end portion of the outer peripheral portion, and the pump body has a forging surface on a part of its outer peripheral surface.
A pen format liquid collection device (10, 110, 310), comprising: an elongate tubular housing (12, 112, 212, 312) able to be held by hand and having an opening at one end; at least one liquid take-up element comprising a capillary (30, 130, 230, 330) mounted in said housing so as to be positioned or positionable to project at said opening, the at least one liquid take-up element then further postionable by hand manipulation of the housing to contact a volume of liquid to thereby take-up a sample of the liquid to be analysed, and at least one retention element (230a, 330a) supported in said housing; wherein the at least one capillary (30, 130, 230, 330) and the at least one retention element (230a, 330a) are arranged whereby they are relatively movable into contact; wherein the at least one retention element (230a, 330a) is adapted on said contact to in turn take-up the sample and retain the sample or a component thereof for in situ analysis or later recovery while protected within the housing (12, 112, 212, 312); wherein the capillary (30, 130, 230, 330) is configured to take-up by capillary action, a predetermined volume portion of the sample and notwithstanding gravity to retain the portion in any orientation of the capillary. an elongate tubular housing (12, 112, 212, 312) able to be held by hand and having an opening at one end; at least one liquid take-up element comprising a capillary (30, 130, 230, 330) mounted in said housing so as to be positioned or positionable to project at said opening, the at least one liquid take-up element then further postionable by hand manipulation of the housing to contact a volume of liquid to thereby take-up a sample of the liquid to be analysed, and at least one retention element (230a, 330a) supported in said housing; wherein the at least one capillary (30, 130, 230, 330) and the at least one retention element (230a, 330a) are arranged whereby they are relatively movable into contact; wherein the at least one retention element (230a, 330a) is adapted on said contact to in turn take-up the sample and retain the sample or a component thereof for in situ analysis or later recovery while protected within the housing (12, 112, 212, 312); wherein the capillary (30, 130, 230, 330) is configured to take-up by capillary action, a predetermined volume portion of the sample and notwithstanding gravity to retain the portion in any orientation of the capillary.
An isolation valve system, comprising: a main body; an actuator body; and a sealing membrane at a high pressure portion of said isolation valve system, mechanically attaching said actuator body to said main body; said sealing membrane sealing said high pressure portion of said isolation valve system from a low pressure portion of said isolation valve system, characterised by a burst plug, arranged against said main body and supporting said actuator body; and an activation arrangement arranged for allowing an at least partial displacement of said burst plug; whereby said sealing membrane being dimensioned to break by action of said high pressure when said actuator body is moved a distance allowed by said at least partial displacement of said burst plug. a main body; an actuator body; and a sealing membrane at a high pressure portion of said isolation valve system, mechanically attaching said actuator body to said main body; said sealing membrane sealing said high pressure portion of said isolation valve system from a low pressure portion of said isolation valve system, characterised by a burst plug, arranged against said main body and supporting said actuator body; and an activation arrangement arranged for allowing an at least partial displacement of said burst plug; whereby said sealing membrane being dimensioned to break by action of said high pressure when said actuator body is moved a distance allowed by said at least partial displacement of said burst plug.
A heat treated coated article comprising: a multi-layer coating supported by a glass substrate, wherein the coating comprises at least one layer comprising silver; wherein the coated article has a ratio T vis /R S of at least 32 after heat treatment (where T vis is visible transmission (%) and R S is sheet resistance of the coating in units of ohms/square) and a ΔE* value (glass side reflective and/or transmissive) of less than or equal to about 8 due to the heat treatment; wherein a layer comprising ZnO or ZnAlO X is located between and contacting each of said layer comprising silver and a layer comprising silicon nitride, and wherein said layer comprising ZnO or ZnAlO X and said layer comprising silicon nitride are located under said layer comprising silver, wherein said layer comprising silicon nitride is non-stoichiometric and is Si-rich. a multi-layer coating supported by a glass substrate, wherein the coating comprises at least one layer comprising silver; wherein the coated article has a ratio T vis /R S of at least 32 after heat treatment (where T vis is visible transmission (%) and R S is sheet resistance of the coating in units of ohms/square) and a ΔE* value (glass side reflective and/or transmissive) of less than or equal to about 8 due to the heat treatment; wherein a layer comprising ZnO or ZnAlO X is located between and contacting each of said layer comprising silver and a layer comprising silicon nitride, and wherein said layer comprising ZnO or ZnAlO X and said layer comprising silicon nitride are located under said layer comprising silver, wherein said layer comprising silicon nitride is non-stoichiometric and is Si-rich.
A method, comprising: placing a portable electronic device that has been rendered at least partially inoperable due to moisture intrusion into a low-pressure chamber; heating the portable electronic device; decreasing pressure within the low-pressure chamber; removing moisture from an interior of the portable electronic device to an exterior of the portable electronic device; increasing the pressure within the low-pressure chamber after said decreasing the pressure; equalizing the pressure within the low-pressure chamber with the pressure outside the low-pressure chamber; removing the portable electronic device from the low-pressure chamber, wherein: decreasing the pressure and increasing the pressure are repeated sequentially before said removing the portable electronic device; controlling a valve connected to the low-pressure chamber to increase the pressure within the low-pressure chamber between successive reductions in the pressure, characterised in that the method further comprises: detecting when a sufficient amount of moisture has been removed from the portable electronic device; and stopping the repeated decreasing the pressure and increasing the pressure after said detecting. placing a portable electronic device that has been rendered at least partially inoperable due to moisture intrusion into a low-pressure chamber; heating the portable electronic device; decreasing pressure within the low-pressure chamber; removing moisture from an interior of the portable electronic device to an exterior of the portable electronic device; increasing the pressure within the low-pressure chamber after said decreasing the pressure; equalizing the pressure within the low-pressure chamber with the pressure outside the low-pressure chamber; removing the portable electronic device from the low-pressure chamber, decreasing the pressure and increasing the pressure are repeated sequentially before said removing the portable electronic device; controlling a valve connected to the low-pressure chamber to increase the pressure within the low-pressure chamber between successive reductions in the pressure, characterised in that the method further comprises: detecting when a sufficient amount of moisture has been removed from the portable electronic device; and stopping the repeated decreasing the pressure and increasing the pressure after said detecting. detecting when a sufficient amount of moisture has been removed from the portable electronic device; and stopping the repeated decreasing the pressure and increasing the pressure after said detecting.
Baking oven comprising an oven cavity with a cavity wall, wherein the cavity wall is at least partially covered by a baking oven insulation, the baking oven insulation comprising at least a first insulating layer composed of a fibre material, a metallic sheet material layer and a second insulating layer at least partially composed of a fibre material, wherein the first and second insulating layers (2, 4) are located at opposite sides of the metallic sheet material layer, wherein the first insulating layer is an inner layer to be arranged immediately at the outer side of a cavity wall of a baking oven and the second insulating layer is an outer layer spaced from the cavity wall of the baking oven, wherein the fibre material of the first insulating layer is made of glass wool with a material density between 20 - 50 kg/m 3, preferably between 30 - 40 kg/m 3, most preferably 35 kg/m 3, or rock wool with a material density between 40 - 60 kg/m 3, preferably 45 kg/m 3 characterised in that the first insulating layer comprises a thickness d 1 and the second insulating layer comprises a thickness d 2, wherein the ratio d1/d2 is in the range between 0.25 and 0.75, the second insulating layer comprising a fibre material with higher material density than the first insulating layer and/or that the second insulating layer is formed by a stack of insulating sub-layers (4.1, 4.2) comprising at least a first and a second sub-layer, wherein said first and second sub-layers (4.1, 4.2) are interconnected such that the second sub-layer (4.2) is adhered to the first sub-layer (4.1), wherein the material density of a second insulating sub-layer (4.2) being spaced from the metallic sheet material layer by means of the first insulating sub-layer (4.1) is at least 10% higher than the material density of the first insulating sub-layer (4.1).
An anti-c-Met/anti-EGFR bispecific antibody comprising an anti-c-Met antibody or an antigen-binding fragment thereof and an anti-EGFR antibody or an antigen-binding fragment thereof, wherein (i) the anti-c-Met antibody or antigen-binding fragment thereof binds to an epitope having 5 to 19 contiguous amino acids of SEQ ID NO: 71, and the epitope comprises the amino acid sequence of SEQ ID NO: 73; and (ii) the anti-EGFR antibody or antigen-binding fragment thereof comprises: a heavy chain comprising the following complementarity determining regions: a) a CDR-H1 comprising the amino acid sequence of SEQ ID NO: 109, b) a CDR-H2 comprising the amino acid sequence of SEQ ID NO: 110, and c) a CDR-H3 comprising the amino acid sequence of SEQ ID NO: 111; and a light chain comprising the following complementarity determining regions: a) a CDR-L1 comprising the amino acid sequence of SEQ ID NO: 112, b) a CDR-L2 comprising the amino acid sequence of SEQ ID NO: 113, and c) a CDR-L3 comprising the amino acid sequence of SEQ ID NO: 114. (i) the anti-c-Met antibody or antigen-binding fragment thereof binds to an epitope having 5 to 19 contiguous amino acids of SEQ ID NO: 71, and the epitope comprises the amino acid sequence of SEQ ID NO: 73; and (ii) the anti-EGFR antibody or antigen-binding fragment thereof comprises: a heavy chain comprising the following complementarity determining regions: a) a CDR-H1 comprising the amino acid sequence of SEQ ID NO: 109, b) a CDR-H2 comprising the amino acid sequence of SEQ ID NO: 110, and c) a CDR-H3 comprising the amino acid sequence of SEQ ID NO: 111; and a light chain comprising the following complementarity determining regions: a) a CDR-L1 comprising the amino acid sequence of SEQ ID NO: 112, b) a CDR-L2 comprising the amino acid sequence of SEQ ID NO: 113, and c) a CDR-L3 comprising the amino acid sequence of SEQ ID NO: 114. a heavy chain comprising the following complementarity determining regions: a) a CDR-H1 comprising the amino acid sequence of SEQ ID NO: 109, b) a CDR-H2 comprising the amino acid sequence of SEQ ID NO: 110, and c) a CDR-H3 comprising the amino acid sequence of SEQ ID NO: 111; and a light chain comprising the following complementarity determining regions: a) a CDR-L1 comprising the amino acid sequence of SEQ ID NO: 112, b) a CDR-L2 comprising the amino acid sequence of SEQ ID NO: 113, and c) a CDR-L3 comprising the amino acid sequence of SEQ ID NO: 114.
Composition comprising A) from 41 to 80 parts by weight, based in each case on the total of the parts by weight of components A+B+C+D, of aromatic polycarbonate, B) from 5 to 40 parts by weight, based in each case on the total of the parts by weight of components A+B+C+D, of polyester, C) from 1 to 15 parts by weight, based in each case on the total of the parts by weight of components A+B+C+D, of rubber-modified graft polymer, D) from 0 to 25 parts by weight, based in each case on the total of the parts by weight of components A+B+C+D, of a flame retardant, E) from 0 to 20 parts by weight, based in each case on the total of the parts by weight of components A+B+C+D = 100, of vinyl (co)polymer, F) from 0 to 50 parts by weight, based in each case on the total of the parts by weight of components A+B+C+D = 100, of additives, where component B is formed from ethylene glycol units and from a mixture of terephthalic acid units and isophthalic acid units with from 2.0 to 4.0% by weight content, based on component B, of isophthalic acid units, and where all of the parts by weight data have been standardized in such a way that the total of the parts by weight of components A+B+C+D in the composition is 100. A) from 41 to 80 parts by weight, based in each case on the total of the parts by weight of components A+B+C+D, of aromatic polycarbonate, B) from 5 to 40 parts by weight, based in each case on the total of the parts by weight of components A+B+C+D, of polyester, C) from 1 to 15 parts by weight, based in each case on the total of the parts by weight of components A+B+C+D, of rubber-modified graft polymer, D) from 0 to 25 parts by weight, based in each case on the total of the parts by weight of components A+B+C+D, of a flame retardant, E) from 0 to 20 parts by weight, based in each case on the total of the parts by weight of components A+B+C+D = 100, of vinyl (co)polymer, F) from 0 to 50 parts by weight, based in each case on the total of the parts by weight of components A+B+C+D = 100, of additives, where component B is formed from ethylene glycol units and from a mixture of terephthalic acid units and isophthalic acid units with from 2.0 to 4.0% by weight content, based on component B, of isophthalic acid units, and where all of the parts by weight data have been standardized in such a way that the total of the parts by weight of components A+B+C+D in the composition is 100.