An interference cancellation apparatus, comprising: a main receive antenna, configured to receive a radio frequency receive signal, and transmit the radio frequency receive signal to a first-type interference canceller; a divider, configured to acquire a radio frequency reference signal generated according to a transmit signal, and transmit the radio frequency reference signal to the first-type interference canceller and a second-type interference reconstructor; the first-type interference canceller, configured to receive the radio frequency reference signal transmitted by the divider and the radio frequency receive signal transmitted by the main receive antenna, and cancel a first-type self-interference component in the radio frequency receive signal according to the radio frequency reference signal to generate a first processed signal, wherein the first-type self-interference component comprises a main-path self-interference component; the second-type interference reconstructor, configured to generate a reconstructed self-interference signal according to a self-interference channel parameter and the radio frequency reference signal transmitted by the divider; a coupler, configured to receive the first processed signal and the reconstructed self-interference signal transmitted by the second-type interference reconstructor, and cancel a second-type self-interference component in the first processed signal according to the reconstructed self-interference signal to generate a second processed signal; a down converter, configured to perform down-conversion processing on the second processed signal to generate a third processed signal; and an analog to digital converter ADC, configured to perform analog to digital conversion on the third processed signal to generate a digital signal; wherein the second-type interference reconstructor is further configured to acquire a digital baseband reference signal, receive the digital signal generated by the analog to digital converter ADC and the radio frequency reference signal transmitted by the divider, and perform self-interference channel estimation according to the digital baseband reference signal and the digital signal to generate the self-interference channel parameter. a main receive antenna, configured to receive a radio frequency receive signal, and transmit the radio frequency receive signal to a first-type interference canceller; a divider, configured to acquire a radio frequency reference signal generated according to a transmit signal, and transmit the radio frequency reference signal to the first-type interference canceller and a second-type interference reconstructor; the first-type interference canceller, configured to receive the radio frequency reference signal transmitted by the divider and the radio frequency receive signal transmitted by the main receive antenna, and cancel a first-type self-interference component in the radio frequency receive signal according to the radio frequency reference signal to generate a first processed signal, wherein the first-type self-interference component comprises a main-path self-interference component; the second-type interference reconstructor, configured to generate a reconstructed self-interference signal according to a self-interference channel parameter and the radio frequency reference signal transmitted by the divider; a coupler, configured to receive the first processed signal and the reconstructed self-interference signal transmitted by the second-type interference reconstructor, and cancel a second-type self-interference component in the first processed signal according to the reconstructed self-interference signal to generate a second processed signal; a down converter, configured to perform down-conversion processing on the second processed signal to generate a third processed signal; and an analog to digital converter ADC, configured to perform analog to digital conversion on the third processed signal to generate a digital signal; wherein the second-type interference reconstructor is further configured to acquire a digital baseband reference signal, receive the digital signal generated by the analog to digital converter ADC and the radio frequency reference signal transmitted by the divider, and perform self-interference channel estimation according to the digital baseband reference signal and the digital signal to generate the self-interference channel parameter.