A cleaning agent, characterized in that it comprises at least a first and a second protease, a) the first protease comprising an amino acid sequence which is at least 95% identical to the amino acid sequence shown in SEQ ID NO. 1 over its entire length and has at least one amino acid substitution at one of the positions 9, 15, 66, 212 and 239 in the numbering according to SEQ ID NO. 1, and b) the second protease being selected from the group formed by b1) protease comprising an amino acid sequence which is at least 95% identical to the amino acid sequence shown in SEQ ID NO. 2 over its entire length and has the amino acid glutamic acid at position 99 in the numbering according to SEQ ID NO. 2; b2) protease comprising an amino acid sequence which is at least 95% identical to the amino acid sequence shown in SEQ ID NO. 2 over its entire length and has the amino acid substitution R99E in combination with at least two additional amino acid substitutions in the numbering according to SEQ ID NO. 2, which amino acid substitutions are selected from the group consisting of S3T, V4I and V199I; and b3) protease comprising an amino acid sequence which is at least 95% identical to the amino acid sequence shown in SEQ ID NO. 1 over its entire length and has the amino acid substitution S99A in combination with an insertion between positions 99 and 100 in the numbering according to BPN', the inserted amino acid being aspartic acid. a) the first protease comprising an amino acid sequence which is at least 95% identical to the amino acid sequence shown in SEQ ID NO. 1 over its entire length and has at least one amino acid substitution at one of the positions 9, 15, 66, 212 and 239 in the numbering according to SEQ ID NO. 1, and b) the second protease being selected from the group formed by b1) protease comprising an amino acid sequence which is at least 95% identical to the amino acid sequence shown in SEQ ID NO. 2 over its entire length and has the amino acid glutamic acid at position 99 in the numbering according to SEQ ID NO. 2; b2) protease comprising an amino acid sequence which is at least 95% identical to the amino acid sequence shown in SEQ ID NO. 2 over its entire length and has the amino acid substitution R99E in combination with at least two additional amino acid substitutions in the numbering according to SEQ ID NO. 2, which amino acid substitutions are selected from the group consisting of S3T, V4I and V199I; and b3) protease comprising an amino acid sequence which is at least 95% identical to the amino acid sequence shown in SEQ ID NO. 1 over its entire length and has the amino acid substitution S99A in combination with an insertion between positions 99 and 100 in the numbering according to BPN', the inserted amino acid being aspartic acid. b1) protease comprising an amino acid sequence which is at least 95% identical to the amino acid sequence shown in SEQ ID NO. 2 over its entire length and has the amino acid glutamic acid at position 99 in the numbering according to SEQ ID NO. 2; b2) protease comprising an amino acid sequence which is at least 95% identical to the amino acid sequence shown in SEQ ID NO. 2 over its entire length and has the amino acid substitution R99E in combination with at least two additional amino acid substitutions in the numbering according to SEQ ID NO. 2, which amino acid substitutions are selected from the group consisting of S3T, V4I and V199I; and b3) protease comprising an amino acid sequence which is at least 95% identical to the amino acid sequence shown in SEQ ID NO. 1 over its entire length and has the amino acid substitution S99A in combination with an insertion between positions 99 and 100 in the numbering according to BPN', the inserted amino acid being aspartic acid.