An apparatus for the detection of agglutination reactions comprising: a. a plurality of probe tips, each of the probe tips comprising: i. a first port configured to permit negative or positive pressure to an internal volume of a probe tip; ii. a sample cavity of said internal volume in fluid communication with said first port; iii. at least one flanking cavity of said internal volume configured to capture particles in the sample after separation of the particles from the remainder of the sample, wherein said flanking cavity is in fluid communication with said sample cavity, the at least one flanking cavity being disposed outwardly radially from the sample cavity and having a primary axis disposed at an acute angle relative to a vertical centre axis of said probe tip; iv. a detection cavity of said internal volume configured for the detection of agglutinated particles within the sample, wherein said detection cavity is in fluid connection with said sample cavity; v. a transition zone of said internal volume disposed between said sample cavity and said detection cavity, said transition zone being configured for rotational mixing of the sample moving back and forth through said transition zone between said detection cavity and said sample cavity through agitation thereof; vi. a second port in fluid connection with said detection cavity, said second port being configured to permit reagents and sample to be aspirated into or dispensed from said internal volume of said probe tip; b. a plurality of holders configured for the placement of the plurality of probe tips; and c. a means for separating the particles in the sample from the remainder of the sample; characterized in that an internal diameter of a wall of the sample cavity is larger than an internal diameter of a wall of the detection cavity, and the transition zone includes a gradual decrease in an internal diameter of a wall from the sample cavity to the detection cavity, wherein the probe tip includes a material that permits detection by means of absorption of light in the detection cavity. a. a plurality of probe tips, each of the probe tips comprising: i. a first port configured to permit negative or positive pressure to an internal volume of a probe tip; ii. a sample cavity of said internal volume in fluid communication with said first port; iii. at least one flanking cavity of said internal volume configured to capture particles in the sample after separation of the particles from the remainder of the sample, wherein said flanking cavity is in fluid communication with said sample cavity, the at least one flanking cavity being disposed outwardly radially from the sample cavity and having a primary axis disposed at an acute angle relative to a vertical centre axis of said probe tip; iv. a detection cavity of said internal volume configured for the detection of agglutinated particles within the sample, wherein said detection cavity is in fluid connection with said sample cavity; v. a transition zone of said internal volume disposed between said sample cavity and said detection cavity, said transition zone being configured for rotational mixing of the sample moving back and forth through said transition zone between said detection cavity and said sample cavity through agitation thereof; vi. a second port in fluid connection with said detection cavity, said second port being configured to permit reagents and sample to be aspirated into or dispensed from said internal volume of said probe tip; i. a first port configured to permit negative or positive pressure to an internal volume of a probe tip; ii. a sample cavity of said internal volume in fluid communication with said first port; iii. at least one flanking cavity of said internal volume configured to capture particles in the sample after separation of the particles from the remainder of the sample, wherein said flanking cavity is in fluid communication with said sample cavity, the at least one flanking cavity being disposed outwardly radially from the sample cavity and having a primary axis disposed at an acute angle relative to a vertical centre axis of said probe tip; iv. a detection cavity of said internal volume configured for the detection of agglutinated particles within the sample, wherein said detection cavity is in fluid connection with said sample cavity; v. a transition zone of said internal volume disposed between said sample cavity and said detection cavity, said transition zone being configured for rotational mixing of the sample moving back and forth through said transition zone between said detection cavity and said sample cavity through agitation thereof; vi. a second port in fluid connection with said detection cavity, said second port being configured to permit reagents and sample to be aspirated into or dispensed from said internal volume of said probe tip; b. a plurality of holders configured for the placement of the plurality of probe tips; and c. a means for separating the particles in the sample from the remainder of the sample; characterized in that an internal diameter of a wall of the sample cavity is larger than an internal diameter of a wall of the detection cavity, and the transition zone includes a gradual decrease in an internal diameter of a wall from the sample cavity to the detection cavity,