A device for treating insomnia by non-invasively applying hypothermal therapy to a subject's frontal cortex, the device comprising: an applicator comprising a thermal transfer region to be worn against the subject's skin over the prefrontal cortex and an integrated eye pad; a hypothermic controller connected to the applicator and configured to control the timing and temperature of cooling of the thermal transfer region, wherein the hypothermic controller is configured to cool the applicator to a first temperature of between 10 °C and 18 °C for a first time period extending at least 15 minutes and cool the applicator to a second temperature of between 20 °C to 25 °C for a second time period extending at least 15 minutes, wherein the temperature and/or timing is controlled based at least on feedback based on EEG, heart rate variability, galvanic skin response, skin temperature measured at a portion of the head not underneath the device, eye motion, core body temperature, body motion, and/or muscle tone; inlet and outlet tubing connecting the applicator to the hypothermic controller and configured for the circulation therethrough of cooling fluid between a reservoir of cooling fluid and the applicator; and a swiveling junction between the applicator and the inlet and outlet tubing to enhance comfort when wearing the applicator; wherein the device can be re-charged. an applicator comprising a thermal transfer region to be worn against the subject's skin over the prefrontal cortex and an integrated eye pad; a hypothermic controller connected to the applicator and configured to control the timing and temperature of cooling of the thermal transfer region, wherein the hypothermic controller is configured to cool the applicator to a first temperature of between 10 °C and 18 °C for a first time period extending at least 15 minutes and cool the applicator to a second temperature of between 20 °C to 25 °C for a second time period extending at least 15 minutes, wherein the temperature and/or timing is controlled based at least on feedback based on EEG, heart rate variability, galvanic skin response, skin temperature measured at a portion of the head not underneath the device, eye motion, core body temperature, body motion, and/or muscle tone; a hypothermic controller connected to the applicator and configured to control the timing and temperature of cooling of the thermal transfer region, wherein the hypothermic controller is configured to cool the applicator to a first temperature of between 10 °C and 18 °C for a first time period extending at least 15 minutes and cool the applicator to a second temperature of between 20 °C to 25 °C for a second time period extending at least 15 minutes, wherein the temperature and/or timing is controlled based at least on feedback based on EEG, heart rate variability, galvanic skin response, skin temperature measured at a portion of the head not underneath the device, eye motion, core body temperature, body motion, and/or muscle tone; inlet and outlet tubing connecting the applicator to the hypothermic controller and configured for the circulation therethrough of cooling fluid between a reservoir of cooling fluid and the applicator; and a swiveling junction between the applicator and the inlet and outlet tubing to enhance comfort when wearing the applicator; wherein the device can be re-charged.