The compound of general formula wherein R 1 represents a C 1 -C 6 -alkyl or C 3 -C 5 -cycloalkyl group, wherein said group is optionally substituted with one substituent selected from the group consisting of hydroxy, C 1 -C 3 -alkoxy-, -NH 2, alkylamino-, dialkylamino-, cyclic amines, -OP(=O) 2; R 2 represents a group selected from R 3 represents a group selected from a fluoro atom, a chloro atom, -SF 5, a C 1 -C 3 -alkyl and a fluoro-C 1 -C 3 -alkyl- group; R 4 represents a hydrogen atom or a fluoro atom; R 5 represents a group selected from a hydrogen atom, cyano, C 1 -C 4 -alkyl-, C 3 -C 4 -alkynyl-, C 3 -C 5 -cycloalkyl-, phenyl, wherein said C 1 -C 4 -alkyl, C 3 -C 5 -cycloalkyl- or phenyl group is optionally substituted with one, two or three substituents, identically or differently, selected from the group consisting of halogen, hydroxy, cyano, C 1 -C 3 -alkyl-, C 1 -C 3 -alkoxy-; R 6, R 7 represent, independently from each other, a group selected from a hydrogen atom, a fluoro atom and a chloro atom; R 8 represents a group selected from a) a C 1 -C 4 -alkyl group, which is optionally substituted with one or two or three substituents, identically or differently, selected from the group consisting of halogen, hydroxy, -NH 2, alkylamino-, dialkylamino-, cyclic amines, cyano, C 1 -C 3 -alkyl-, fluoro-C 1 -C 2 -alkyl-, C 1 -C 2 -fluoroalkoxy-, C 1 -C 3 -alkoxy-, C 2 -C 3 -alkenyl-, C 2 -C 3 -alkynyl-, C 3 -C 5 -cycloalkyl-; b) a phenyl-C 1 -C 2 -alkyl- group, the phenyl group of which is optionally substituted with one or two or three substituents, identically or differently, selected from the group consisting of halogen, hydroxy, -NH 2, alkylamino-, dialkylamino-, cyclic amines, cyano, C 1 -C 3 -alkyl-, fluoro-C 1 -C 2 -alkyl-, C 1 -C 2 -fluoroalkoxy-, C 1 -C 3 -alkoxy-; the term "cyclic amine" meaning a saturated, monocyclic group with 4 to 10, preferably 4 to 7 ring atoms of which at least one ring atom is a nitrogen atom, suitable cyclic amines especially being azetidine, pyrrolidine, piperidine, piperazine, 1-methylpiperazine, morpholine, thiomorpholine, which could be optionally substituted by one or two methyl groups, or an enantiomer, diastereomer, physiologically acceptable salt, solvate or salt of solvate thereof. R 1 represents a C 1 -C 6 -alkyl or C 3 -C 5 -cycloalkyl group, wherein said group is optionally substituted with one substituent selected from the group consisting of hydroxy, C 1 -C 3 -alkoxy-, -NH 2, alkylamino-, dialkylamino-, cyclic amines, -OP(=O) 2; R 2 represents a group selected from R 3 represents a group selected from a fluoro atom, a chloro atom, -SF 5, a C 1 -C 3 -alkyl and a fluoro-C 1 -C 3 -alkyl- group; R 4 represents a hydrogen atom or a fluoro atom; R 5 represents a group selected from a hydrogen atom, cyano, C 1 -C 4 -alkyl-, C 3 -C 4 -alkynyl-, C 3 -C 5 -cycloalkyl-, phenyl, wherein said C 1 -C 4 -alkyl, C 3 -C 5 -cycloalkyl- or phenyl group is optionally substituted with one, two or three substituents, identically or differently, selected from the group consisting of halogen, hydroxy, cyano, C 1 -C 3 -alkyl-, C 1 -C 3 -alkoxy-; R 6, R 7 represent, independently from each other, a group selected from a hydrogen atom, a fluoro atom and a chloro atom; R 8 represents a group selected from a) a C 1 -C 4 -alkyl group, which is optionally substituted with one or two or three substituents, identically or differently, selected from the group consisting of halogen, hydroxy, -NH 2, alkylamino-, dialkylamino-, cyclic amines, cyano, C 1 -C 3 -alkyl-, fluoro-C 1 -C 2 -alkyl-, C 1 -C 2 -fluoroalkoxy-, C 1 -C 3 -alkoxy-, C 2 -C 3 -alkenyl-, C 2 -C 3 -alkynyl-, C 3 -C 5 -cycloalkyl-; b) a phenyl-C 1 -C 2 -alkyl- group, the phenyl group of which is optionally substituted with one or two or three substituents, identically or differently, selected from the group consisting of halogen, hydroxy, -NH 2, alkylamino-, dialkylamino-, cyclic amines, cyano, C 1 -C 3 -alkyl-, fluoro-C 1 -C 2 -alkyl-, C 1 -C 2 -fluoroalkoxy-, C 1 -C 3 -alkoxy-; a) a C 1 -C 4 -alkyl group, which is optionally substituted with one or two or three substituents, identically or differently, selected from the group consisting of halogen, hydroxy, -NH 2, alkylamino-, dialkylamino-, cyclic amines, cyano, C 1 -C 3 -alkyl-, fluoro-C 1 -C 2 -alkyl-, C 1 -C 2 -fluoroalkoxy-, C 1 -C 3 -alkoxy-, C 2 -C 3 -alkenyl-, C 2 -C 3 -alkynyl-, C 3 -C 5 -cycloalkyl-; b) a phenyl-C 1 -C 2 -alkyl- group, the phenyl group of which is optionally substituted with one or two or three substituents, identically or differently, selected from the group consisting of halogen, hydroxy, -NH 2, alkylamino-, dialkylamino-, cyclic amines, cyano, C 1 -C 3 -alkyl-, fluoro-C 1 -C 2 -alkyl-, C 1 -C 2 -fluoroalkoxy-, C 1 -C 3 -alkoxy-;