mhurhangee/ep-ind-claims huggingface dataset:
Mixture of compounds, said mixture comprising a mixture of compounds according to the general formula wherein R 1 is C 1 -C 4 -alkyl, linear or branched, or hydrogen, R 2 is -CH 2 CH 2 R 1, each G 1 is glucose or xylose, wherein in the range of from 70 to 95 % mole-% are glucose and from 5 to 30 mole-% are xylose, and the average of x is in the range of from 1.1 to 4. R 1 is C 1 -C 4 -alkyl, linear or branched, or hydrogen, R 2 is -CH 2 CH 2 R 1, each G 1 is glucose or xylose, wherein in the range of from 70 to 95 % mole-% are glucose and from 5 to 30 mole-% are xylose, and the average of x is in the range of from 1.1 to 4.
A granule comprising a complex fiber of a cellulose fiber with inorganic particles, and having a particle size of 0.1 to 10 mm and a water content of less than 60 %, wherein the inorganic particles comprise a metal salt of calcium, magnesium, barium or aluminum, or metal particles containing titanium, copper or zinc, or a silicate.
An implantable drug depot comprising a therapeutically effective amount of an alpha adrenergic agonist, the drug depot being in a form implantable at a target tissue site beneath the skin, the target tissue site comprising at least one of muscle, ligament, tendon, cartilage, spinal disc, spinal foraminal space, near the spinal nerve root, facet or spinal canal, for use in reducing, preventing or treating pain and/or inflammation, wherein the drug depot comprises a pharmaceutical formulation comprising the alpha adrenergic agonist and a polymer selected from polylactide, poly (D,L-Lactide), D,L-lactide-co-caprolactone, poly(L-Lactide-co caprolactone) or combination thereof, wherein the depot the depot is capable of releasing (i) about 5% to about 20% of the alpha adrenergic agonist relative to a total amount of the alpha adrenergic agonist loaded in the drug depot over a first period of up to 72 hours and (ii) about 21% to about 99% of the alpha adrenergic agonist relative to a total amount of the alpha adrenergic agonist loaded in the drug depot over a subsequent period of up to 6 months wherein the alpha adrenergic agonist is chlonidine hydrochloride and the clonidine hydrochloride and the polymer are the only components of the pharmaceutical formulation.
A sensor system comprising: a mat for placement over a patient's mattress; at least one sensor located in a hole in the mat; each sensor comprising: a sensor housing, a sound vibration sensing element in the form of a membrane, and means for amplifying sensed sounds; and wherein the membrane is coated/covered with a flexible and/or deformable layer which transfers breath sounds to the membrane without significant attenuating those breath sounds, the breath sounds having a frequency of between 100 Hz and 2000 Hz; characterized in that the sensor is further comprising an elastomeric envelope/container in which the sensor housing is mounted, the envelope/container mounting the sensor in the mat and acting as an independent suspension means that suspends the sensor in the hole and compresses the sensor against a patient overlying the mat. a mat for placement over a patient's mattress; at least one sensor located in a hole in the mat; each sensor comprising: a sensor housing, a sound vibration sensing element in the form of a membrane, and means for amplifying sensed sounds; and wherein the membrane is coated/covered with a flexible and/or deformable layer which transfers breath sounds to the membrane without significant attenuating those breath sounds, the breath sounds having a frequency of between 100 Hz and 2000 Hz; characterized in that the sensor is further comprising an elastomeric envelope/container in which the sensor housing is mounted, the envelope/container mounting the sensor in the mat and acting as an independent suspension means that suspends the sensor in the hole and compresses the sensor against a patient overlying the mat.
A method of communicating a classical message M between distant parties A and B over a lossy and/or noisy public channel F connecting A and B, comprising the steps of: - sharing a short-term-secure key K between A and B, - encoding at A the classical message M as a quantum codeword, A using the shared key to encode the classical message M into an encrypted codeword rho1(M,K) belonging to a publicly known quantum code C; - communicating the encrypted codeword rho1(M,K) from A to B over the channel F whose output is codeword rho2(M,K); - unitarily transforming rho2(M,K) into rho3(M,K) by using a N-mode interferometer I controlled by B placed at the output of channel F and keyed by K;, - determining an estimate Mest of M, locally at B, by performing a measurement on rho3(M, K) and by processing said measurement using the shared key K. - sharing a short-term-secure key K between A and B, - encoding at A the classical message M as a quantum codeword, A using the shared key to encode the classical message M into an encrypted codeword rho1(M,K) belonging to a publicly known quantum code C; - communicating the encrypted codeword rho1(M,K) from A to B over the channel F whose output is codeword rho2(M,K); - unitarily transforming rho2(M,K) into rho3(M,K) by using a N-mode interferometer I controlled by B placed at the output of channel F and keyed by K;, - determining an estimate Mest of M, locally at B, by performing a measurement on rho3(M, K) and by processing said measurement using the shared key K.
A coil carrier for an electromagnetic actuator, with a winding section for an energisable winding, with an injection moulded plastic body, with a first yoke disc designed as an annular disc, having a central passage opening, and affixed on a first axial face of the winding section, and with an armature guide chamber enclosed by the plastic body for the accommodation of an axially adjustable armature, wherein a second yoke disc is provided on an axial face of the winding section that is located opposite to the first axial face, wherein the first yoke disk has at least one recess that is open in the radially inwards direction towards the passage opening, and in that, the first yoke disk is affixed to the plastic body by means of overmoulding, such that plastic body material fills the at least one recess and projects radially inwards beyond the recess into the central passage opening and forms a guide for the armature, and in that, the second yoke disk is affixed to the plastic body by means of overmoulding.
A source terminal connected to at least one other terminal, the source terminal comprising: a data copy module that copies data from an application interface associated with an application to a clipboard on the source terminal, a data retrieving module that retrieves the data saved on the clipboard of the source terminal, an account module that determines user account information of the application on the source terminal, a target identifying module that identifies, based on the user account information, at least one other terminal as a target terminal to receive the retrieved data, wherein the target identifying module identifying the at least one other terminal to be the target terminal comprises determining whether the user account information matches account information associated with the application on at least one other terminal, and a transmitting module that transmits the retrieved data to the identified target terminal. a data copy module that copies data from an application interface associated with an application to a clipboard on the source terminal, a data retrieving module that retrieves the data saved on the clipboard of the source terminal, an account module that determines user account information of the application on the source terminal, a target identifying module that identifies, based on the user account information, at least one other terminal as a target terminal to receive the retrieved data, wherein the target identifying module identifying the at least one other terminal to be the target terminal comprises determining whether the user account information matches account information associated with the application on at least one other terminal, and a transmitting module that transmits the retrieved data to the identified target terminal.
A method for accessing a target user plane, UP, device performed by an apparatus for accessing the target UP device, wherein the method comprises: • obtaining access line information and user information of a terminal (step 301); • obtaining a service level agreement, SLA, level of the terminal based on the user information, wherein the SLA level is used to indicate a level of quality of service of the terminal (step 302); • determining the target UP device based on the SLA level (step 303); and • controlling, based on the access line information, the terminal to access the target UP device (step 306). • obtaining access line information and user information of a terminal (step 301); • obtaining a service level agreement, SLA, level of the terminal based on the user information, wherein the SLA level is used to indicate a level of quality of service of the terminal (step 302); • determining the target UP device based on the SLA level (step 303); and • controlling, based on the access line information, the terminal to access the target UP device (step 306).
Aerosol-generating device for generating an aerosol by inductive heating of an aerosol-forming substrate, the device comprising: a device housing comprising a cavity (20, 120) configured for removably receiving the aerosol-forming substrate to be heated; an inductive heating arrangement comprising at least one induction coil (31, 131) for generating a varying magnetic field within the cavity (20, 120), wherein the induction coil (31, 131) is arranged around at least a portion of the receiving cavity (20, 120); a flux concentrator (33, 133) arranged around at least a portion of the induction coil (31, 131) and configured to distort the varying magnetic field of the at least one inductive heating arrangement towards the cavity (20, 120) during use of the device, wherein the flux concentrator (33, 133) comprise a multi-layer flux concentrator foil (35, 135, 235) having at least one magnetic layer (36, 236) laminated with at least a first support layer (37, 237), wherein the magnetic layer (36, 236) comprises a plurality of separated fragments of a soft magnetic alloy, characterised in that the plurality of separated fragments are arranged in a pattern comprising a plurality of crack centers, wherein a plurality of cracks spread radially outwards from each crack center in a web-shaped pattern. a device housing comprising a cavity (20, 120) configured for removably receiving the aerosol-forming substrate to be heated; an inductive heating arrangement comprising at least one induction coil (31, 131) for generating a varying magnetic field within the cavity (20, 120), wherein the induction coil (31, 131) is arranged around at least a portion of the receiving cavity (20, 120); a flux concentrator (33, 133) arranged around at least a portion of the induction coil (31, 131) and configured to distort the varying magnetic field of the at least one inductive heating arrangement towards the cavity (20, 120) during use of the device, wherein the flux concentrator (33, 133) comprise a multi-layer flux concentrator foil (35, 135, 235) having at least one magnetic layer (36, 236) laminated with at least a first support layer (37, 237), wherein the magnetic layer (36, 236) comprises a plurality of separated fragments of a soft magnetic alloy, characterised in that the plurality of separated fragments are arranged in a pattern comprising a plurality of crack centers, wherein a plurality of cracks spread radially outwards from each crack center in a web-shaped pattern.
A household care composition which comprises a polydimethylsiloxane-polyether copolymers with amino and/or quaternary ammonium groups obtainable by a process comprising the steps: a) a diepoxide is first reacted with at least one amine compound to give a chain-extended adduct bearing a terminal glycidyl group, the molar ratio of diepoxide to amine being variable but at least greater than 1: 1, and b) this intermediate is then reacted with a linear polysiloxane bearing a terminal secondary amino group, c) optionally, the nitrogen atoms can be completely or partially quaternized at any point in this process by adding acids or alkylating reagents, and d) also optionally, water or organic compounds selected from the group of the polyethers, polyols or alcohols can be added as diluents, emulsifiers or modifiers; there making said polydimethylsiloxane-polyether copolymers with amino and/or quaternary ammonium groups, said composition being characterized in that the compounds used in reaction step (b) are linear polysiloxanes which have terminal secondary amino groups and are of the formula where R is a methyl group, R 1 is any hydrocarbon radical, X is a divalent linear or branched hydrocarbon radical which has 1-20 carbon atoms and may be interrupted by nitrogen atoms or aminic groups, and n is an integer from 1 to 500. a) a diepoxide is first reacted with at least one amine compound to give a chain-extended adduct bearing a terminal glycidyl group, the molar ratio of diepoxide to amine being variable but at least greater than 1: 1, and b) this intermediate is then reacted with a linear polysiloxane bearing a terminal secondary amino group, c) optionally, the nitrogen atoms can be completely or partially quaternized at any point in this process by adding acids or alkylating reagents, and d) also optionally, water or organic compounds selected from the group of the polyethers, polyols or alcohols can be added as diluents, emulsifiers or modifiers; there making said polydimethylsiloxane-polyether copolymers with amino and/or quaternary ammonium groups, R is a methyl group, R 1 is any hydrocarbon radical, X is a divalent linear or branched hydrocarbon radical which has 1-20 carbon atoms and may be interrupted by nitrogen atoms or aminic groups, and n is an integer from 1 to 500.
A textured composition forming a lamellar gel network in an oil-in-water system and which has the constituents: - an emulsifier combination composed of 0.05 to 3.00% by weight of at least one anionic emulsifier and 0.15 to 9.00% by weight of at least one fatty alcohol, - 0.01 to 5.00% by weight of at least one hydrocolloid and - 3.00 to 15.00 % by weight of at least one oil and/or wax, and - made up to 100% by weight with water, wherein the anionic emulsifier comprises at least one emulsifier from the group comprising salts of fatty acids, salts of fatty acids in combination with mono-/diglycerides of fatty acids, salts of stearoyl lactic acid, salts of stearoyl glutamic acid or alkyl glutamates, alkyl phosphates, alkyl sulfates, alkyl sarcosinates, salts of alkylsulfosuccinic acid and salts of citric acid esters and the ratio of anionic emulsifier to fatty alcohol is in the range from 1:6 to 2:3. - an emulsifier combination composed of 0.05 to 3.00% by weight of at least one anionic emulsifier and 0.15 to 9.00% by weight of at least one fatty alcohol, - 0.01 to 5.00% by weight of at least one hydrocolloid and - 3.00 to 15.00 % by weight of at least one oil and/or wax, and - made up to 100% by weight with water,
A compound having the formula N-(4-{[4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl]oxylbutyl)octadecanamide, or a pharmaceutically acceptable salt thereof, for use in treating a viral, bacterial, fungal, or parasitic disease.
A system to monitor user technique of an inhaler device configured for delivery of a medicament, said system comprising: a microphone adapted for sensing sound made during operation of an inhaler device; processing circuitry operable to process a data signal obtained from the microphone, wherein said data signal comprises acoustic information sensed, the processing circuitry is adapted to determine inhalation and exhalation breath characteristics that occur during use, by analysing temporal and spectral components of the acoustic information sensed and processed to differentiate between an inhalation and an exhalation, based on both the temporal and spectral components, characterised in that the processing circuitry further comprises means for identifying a medicament priming or blistering characteristic of the device to identify that a medicament is about to be delivered before an inhalation by analysing an acoustic signal generated by a lever mechanism of the inhaler device, adapted to release the medicament that generates a unique energy profile of the lever mechanism convolved with the noise of release of the medicament. a microphone adapted for sensing sound made during operation of an inhaler device; processing circuitry operable to process a data signal obtained from the microphone, wherein said data signal comprises acoustic information sensed, the processing circuitry is adapted to determine inhalation and exhalation breath characteristics that occur during use, by analysing temporal and spectral components of the acoustic information sensed and processed to differentiate between an inhalation and an exhalation, based on both the temporal and spectral components, characterised in that the processing circuitry further comprises means for identifying a medicament priming or blistering characteristic of the device to identify that a medicament is about to be delivered before an inhalation by analysing an acoustic signal generated by a lever mechanism of the inhaler device, adapted to release the medicament that generates a unique energy profile of the lever mechanism convolved with the noise of release of the medicament.
An ophthalmic lens comprising: an anterior surface; a posterior surface; and at least one diffraction grating disposed on at least one of the anterior surface and the posterior surface, the at least one diffraction grating including a plurality of zones corresponding to a plurality of distance ranges from a center of the at least one of the anterior surface and the posterior surface, the plurality of zones including a first zone corresponding to a first distance range, a second zone corresponding to a second distance range further from the center than the first distance range and a repeat zone corresponding to a third distance range further from the center than the second distance range, the first zone including at least a first echelette having a first step height and a first radius of curvature, characterised in that the second zone including at least a second echelette having a second step height and a second radius of curvature different from the first radius of curvature, the repeat zone including at least a third echelette having the first step height and the first radius of curvature of the first zone, wherein the first zone and the repeat zone correspond to a shorter focal length for near vision, and the second zone corresponds to a longer focal length for distance vision, such that, for individuals with larger pupil sizes, more light energy reaching the pupil is dedicatable to near vision. an anterior surface; a posterior surface; and at least one diffraction grating disposed on at least one of the anterior surface and the posterior surface, the at least one diffraction grating including a plurality of zones corresponding to a plurality of distance ranges from a center of the at least one of the anterior surface and the posterior surface, the plurality of zones including a first zone corresponding to a first distance range, a second zone corresponding to a second distance range further from the center than the first distance range and a repeat zone corresponding to a third distance range further from the center than the second distance range, the first zone including at least a first echelette having a first step height and a first radius of curvature, characterised in that the second zone including at least a second echelette having a second step height and a second radius of curvature different from the first radius of curvature, the repeat zone including at least a third echelette having the first step height and the first radius of curvature of the first zone, wherein the first zone and the repeat zone correspond to a shorter focal length for near vision, and the second zone corresponds to a longer focal length for distance vision, such that, for individuals with larger pupil sizes, more light energy reaching the pupil is dedicatable to near vision.
Packaging machine for packaging products, in particular food, wherein the packaging machine comprises at least one high-pressure treatment station for high-pressure treatment of the products contained in the packagings, and at least one transport container for accommodating products during the high-pressure treatment of the products is provided, characterized in that the packaging machine comprises at least one packaging station for producing packagings that accommodate products, and in that a central control system is provided for the packaging station and the high-pressure treatment station, and in that a gripper for loading or unloading the transport container is provided at a loading station and/or at an unloading station, wherein the gripper or grippers also is/are connected with the central control system.
A process for the preparation of a poly(D,L lactide-co-glycolide) polymer microspheres of octreotide acetate, comprising: a. dissolving octreotide acetate in at least one organic solvent miscible in water, and optionally containing also water, to form a water phase; b. forming an oil-in-water or water-in-oil-water emulsion in a suitable oil phase comprising an organic solution of the poly(D,L lactide-co-glycolide) polymer, the solution being non-miscible with the water phase wherein said organic solution of the poly(D,L lactide-co-glycolide) polymer is cooled down to 5°C or below; c. evaporating the at least one organic solvent used in step (a) from the emulsion to form the microspheres by controlling the temperature during the evaporation step and increasing the temperature during the evaporation step with a rate of 0.1°C/min to 1°C/min; wherein the in-vivo and in-vitro release characteristics of octreotide acetate from the microspheres is controlled by selection of the rate of increasing the temperature during the evaporation step. a. dissolving octreotide acetate in at least one organic solvent miscible in water, and optionally containing also water, to form a water phase; b. forming an oil-in-water or water-in-oil-water emulsion in a suitable oil phase comprising an organic solution of the poly(D,L lactide-co-glycolide) polymer, the solution being non-miscible with the water phase wherein said organic solution of the poly(D,L lactide-co-glycolide) polymer is cooled down to 5°C or below; c. evaporating the at least one organic solvent used in step (a) from the emulsion to form the microspheres by controlling the temperature during the evaporation step and increasing the temperature during the evaporation step with a rate of 0.1°C/min to 1°C/min;
A compound having Formula IA: wherein R 1 is a member selected from the group consisting of hydrogen, halo and C 1 -C 6 alkyl; R 4 is a member selected from the group consisting of C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 10 cycloalkyl, C 1 -C 6 alkyloxy, C 3 -C 10 cycloalkyloxy, (C 3 -C 10 cycloalkyl)C 1 -C 3 alkyloxy, (C 3 -C 7 cycloalkyl)C 3 -C 5 alkenyloxy, and (C 3 -C 7 cycloalkyl)C 3 -C 5 alkynyloxy, and, additionally, when R 1 is chloro, R 4 may be - -CH 3 or -CH -CH 3; and Q is of formulae Q 1A: wherein R 11 is hydroxy; or pharmaceutically acceptable salt thereof; or a carboxylate ester thereof. R 1 is a member selected from the group consisting of hydrogen, halo and C 1 -C 6 alkyl; R 4 is a member selected from the group consisting of C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 10 cycloalkyl, C 1 -C 6 alkyloxy, C 3 -C 10 cycloalkyloxy, (C 3 -C 10 cycloalkyl)C 1 -C 3 alkyloxy, (C 3 -C 7 cycloalkyl)C 3 -C 5 alkenyloxy, and (C 3 -C 7 cycloalkyl)C 3 -C 5 alkynyloxy, and, additionally, when R 1 is chloro, R 4 may be - -CH 3 or -CH -CH 3; and Q is of formulae Q 1A: wherein R 11 is hydroxy; or pharmaceutically acceptable salt thereof; or a carboxylate ester thereof.