mhurhangee/ep-ind-claims huggingface dataset:
An apparatus comprising: (a) an opening bounded in part by a strike jamb; (b) a panel mounted relative to said opening so as to be displaceable between an open position in which said panel is separated from said strike jamb to leave at least part of said opening open and a closed position in which said panel closes against said strike jamb; and (c) a lock mechanism associated with said strike jamb, said lock mechanism comprising a locking element displaceable relative to said strike jamb along a path of motion from a released position in which said panel can be separated from said strike jamb to a locked position in which said locking element obstructs displacement of said panel from said strike jamb, contact surfaces (102, 104) of said locking element and said panel being such that a force applied to said panel directed to open said panel does not generate a force acting to displace said locking element back along said path of motion, wherein said locking element provides an input surface deployed so as to be displaced by an actuating surface of said panel during a closing motion of said panel from said open position to said closed position, characterized in that said input surface moving as a unit with said locking element so as to undergo the same solid body motion as said locking element, such that displacement of said input surface by the closing motion of said panel displaces said locking element towards said locked position. (a) an opening bounded in part by a strike jamb; (b) a panel mounted relative to said opening so as to be displaceable between an open position in which said panel is separated from said strike jamb to leave at least part of said opening open and a closed position in which said panel closes against said strike jamb; and (c) a lock mechanism associated with said strike jamb, said lock mechanism comprising a locking element displaceable relative to said strike jamb along a path of motion from a released position in which said panel can be separated from said strike jamb to a locked position in which said locking element obstructs displacement of said panel from said strike jamb, contact surfaces (102, 104) of said locking element and said panel being such that a force applied to said panel directed to open said panel does not generate a force acting to displace said locking element back along said path of motion,
A solid pharmaceutical composition comprising the SGLT-2 inhibitor 1-chloro-4-(β-D-glucopyranos-1-yl)-2-[4-( -tetrahydrofuran-3-yloxy)-benzyl]-benzene, metformin hydrochloride and one or more pharmaceutical excipients, wherein the SGLT-2 inhibitor is present in a dosage strength of 5 mg or 12.5 mg, and wherein metformin hydrochloride is present in a dosage strength of 500 mg, 850 mg or 1000 mg, and wherein the solid pharmaceutical composition comprises copovidone as a binder.
A filter frame for receiving a media pack, the filter frame comprising a front plate, and first and second gable plates arranged at opposite ends (122, 124) of the front plate and primarily extending perpendicular to the front plate, wherein the front plate comprises a groove at each of said ends (122, 124), wherein a front edge portion of each gable plate has been received in a respective one of the grooves, and wherein each gable plate comprises a retainment member comprising a snap-lock element arranged at the front edge portion, which retainment member has been engaged with a complementary retainment member of the front plate.
A power operated rotary knife comprising: an annular rotary knife blade including a wall defining a knife blade bearing surface; a blade housing including a wall defining a blade housing bearing surface; and a blade - blade housing bearing structure disposed between the knife blade bearing surface and the blade housing bearing surface, the blade - blade housing bearing structure supporting the knife blade for rotation with respect to the blade housing about a knife blade central axis, the blade - blade housing bearing structure including an elongated rolling bearing strip which extends circumferentially around the knife blade central axis between the knife blade bearing surface and the blade housing bearing surface, characterized in that the elongated rolling bearing strip comprises a plurality of rolling bearings disposed in spaced apart relation and a flexible separator cage, and the elongated rolling bearing strip is arranged to move, when the power operated rotary knife is in operation, circumferentially in an annular passageway defined between the knife blade bearing surface and the blade housing bearing surface. an annular rotary knife blade including a wall defining a knife blade bearing surface; a blade housing including a wall defining a blade housing bearing surface; and a blade - blade housing bearing structure disposed between the knife blade bearing surface and the blade housing bearing surface, the blade - blade housing bearing structure supporting the knife blade for rotation with respect to the blade housing about a knife blade central axis, the blade - blade housing bearing structure including an elongated rolling bearing strip which extends circumferentially around the knife blade central axis between the knife blade bearing surface and the blade housing bearing surface, characterized in that the elongated rolling bearing strip comprises a plurality of rolling bearings disposed in spaced apart relation and a flexible separator cage, and the elongated rolling bearing strip is arranged to move, when the power operated rotary knife is in operation, circumferentially in an annular passageway defined between the knife blade bearing surface and the blade housing bearing surface.
Refrigerator with a heat-insulating housing, which comprises a foamed hollow body, wherein a component (32, 33) in contact with the foam filling the hollow body is attached to a wall (13, 31) of the hollow body, wherein the component (32, 33) is embodied for assembly on an opening (14, 29, 30) of the wall (13, 31) and is provided with a component main body (1, 12) and a flexible apron projecting from the main body (1, 12), characterised in that the apron consisting of a more flexible material than the main body (1, 12) is moulded tightly against the main body (1, 12), wherein the main body (1, 12) has latching means (3, 19, 20, 21) for latching in the opening (14, 29, 30).
An anti-CD38 antibody for use in treating multiple myeloma in a subject, wherein the treatment comprises administration of the anti-CD38 antibody in combination with carfilzomib, wherein the subject has relapsed after at least two prior therapies for multiple myeloma with bortezomib, thalidomide, and/or lenalidomide, or has been refractory to prior therapy for multiple myeloma, wherein the anti-CD38 antibody comprises a heavy chain comprising three sequential CDRs having amino acid sequences of SEQ ID NOs: 13, 81, and 15, and a light chain comprising three sequential CDRs having amino acid sequences of SEQ ID NOs: 16, 17 and 18.
A method for detecting the expression of survival motor neuron protein, comprising the steps of: labeling SMN protein in a sample containing nucleated cells derived from blood with a first fluorescent dye; labeling the nuclei of the nucleated cells in the sample with a second fluorescent dye; selecting a cell population of the nucleated cells whose nuclei and SMN protein are labeled; and detecting the expression of the SMN protein based on the label for the SMN protein in the selected cell population, wherein said detection step comprises measuring an amount of the SMN protein expressed. labeling SMN protein in a sample containing nucleated cells derived from blood with a first fluorescent dye; labeling the nuclei of the nucleated cells in the sample with a second fluorescent dye; selecting a cell population of the nucleated cells whose nuclei and SMN protein are labeled; and detecting the expression of the SMN protein based on the label for the SMN protein in the selected cell population, wherein said detection step comprises measuring an amount of the SMN protein expressed.
A fastening apparatus for fastening an apparatus to a device, comprising an apparatus-side first part which is fastenable or fastened or attached to the apparatus and which has a first surface region facing the device; a device-side second part which is fastenable or fastened or attached to the device and which is fastened or fastenable to the first part and which has a second surface region facing the apparatus and the first surface region, wherein one of the two parts has at least one centering pin and the other of the two parts has at least one corresponding centering opening into which the centering pin can enter to align the two parts, wherein one or more damping elements composed of a resilient material, in particular of an elastic material, preferably plastic, are attached to one of the two surface regions and come into contact with the other of the two surface regions on the fastening; and a clamping element for jointly clamping the two parts so that they are held aligned and pressed toward one another, characterized in that the first part has a first plate which can have an angular or a round or a circular outline whose side remote from the apparatus has the first surface region in which the centering pin is disposed and whose side facing the apparatus has a first fastening means toward the apparatus, preferably a first threaded pin which can be formed coaxially with the centering pin.
A passenger car winter tyre equipped with studs for normal road use, characterized in that the shape of the stud together with the elasticity of the rubber compound of the winter tyre create a piercing force of less than 120 N on the stud, wherein the diameter of the bottom flange of the stud (øb) is about 7.5 mm or less and the elasticity of the rubber compound of the tyre is 50-80 "Shores", wherein the number of studs in the tyre is greater than 50 studs per one meter of rolling circumference.
An electrical connection structure comprising: a first unit including a terminal; and a second unit including a connection terminal, wherein the electrical connection structure is configured by mounting the second unit to the first unit such that the connection terminal is electrically connected to the terminal, wherein the terminal has a plate-shaped tab, wherein the connection terminal includes a receptacle formed with a connection groove into which the tab is inserted, and a spring contact provided on inner side surfaces of the connection groove, and wherein the spring contact comes into elastic contact with outer surfaces of the tab inserted into the connection groove, characterized in that the electrical connection structure further comprises a third unit including an electric wire and another connection terminal provided at an end portion of the electric wire, the connection terminal of the third unit is connected to the terminal of the first unit such that the spring contact of the receptacle comes into elastic contact with the outer surfaces of the tab, the terminal comprises a main body portion, a pair of leg portions and a pair of tabs, the tabs are bent and extend upward in a direction opposite to the leg portions at the front and rear side edges of the main body portion. a first unit including a terminal; and a second unit including a connection terminal, wherein the electrical connection structure is configured by mounting the second unit to the first unit such that the connection terminal is electrically connected to the terminal, wherein the terminal has a plate-shaped tab, wherein the connection terminal includes a receptacle formed with a connection groove into which the tab is inserted, and a spring contact provided on inner side surfaces of the connection groove, and wherein the spring contact comes into elastic contact with outer surfaces of the tab inserted into the connection groove, characterized in that the electrical connection structure further comprises a third unit including an electric wire and another connection terminal provided at an end portion of the electric wire, the connection terminal of the third unit is connected to the terminal of the first unit such that the spring contact of the receptacle comes into elastic contact with the outer surfaces of the tab, the terminal comprises a main body portion, a pair of leg portions and a pair of tabs, the tabs are bent and extend upward in a direction opposite to the leg portions at the front and rear side edges of the main body portion.
Front flap for a vehicle, in particular motor vehicle, which front flap has an external sheet, where in a predetermined region or in the entire region of the front flap there is at least one inertial mass arranged underneath the external sheet, where the said inertial mass is formed by a flexible heavy layer (5a, 5b), characterized in that the inertial mass in the form of the heavy layer (5a, 5b) comprises bitumen composition, and that the plastics composition moreover comprises foreign plastic.
Composition comprising at least one lipase, at least one branched polyetheramine polyol with a polydispersity (M w /M n) in the range of from 5 to 25, wherein said branched polyetheramine polyol is based on a polycondensation product of at least one trialkanolamine. at least one lipase, at least one branched polyetheramine polyol with a polydispersity (M w /M n) in the range of from 5 to 25, wherein said branched polyetheramine polyol is based on a polycondensation product of at least one trialkanolamine.
An assembly comprising a chassis of a railway vehicle, at least one wheel bearing shaft, which is an axle equipped with two wheels or a half-axle equipped with a wheel, and at least one connection device provided to connect said wheel bearing shaft to the chassis, the wheel bearing shaft being able to pivot with respect to said chassis about a substantially vertical axis, the connection device comprising the following means: • a control actuator comprising a body and a movable part, the body of said control actuator being provided to be connected to the chassis of the vehicle; • a control rod, a first end of which is mounted by a hinge at the free end of the movable part of the control actuator, while its second end is mounted by another hinge on the chassis of the vehicle; • a suspension arm carrying a lateral end of the wheel bearing shaft in an intermediate, preferably substantially median, position between a first end and a second end of said suspension arm, • a suspension device comprising at least one suspension provided between the chassis of the vehicle and the second end of the suspension arm for suspending and damping vertical movements; these means being arranged so that when the control rod is pivoted by the control actuator, the wheel bearing shaft pivots with respect to the chassis about a vertical axis, characterised in that the first end of the suspension arm is mounted articulated to the control rod by a hinge. • a control actuator comprising a body and a movable part, the body of said control actuator being provided to be connected to the chassis of the vehicle; • a control rod, a first end of which is mounted by a hinge at the free end of the movable part of the control actuator, while its second end is mounted by another hinge on the chassis of the vehicle; • a suspension arm carrying a lateral end of the wheel bearing shaft in an intermediate, preferably substantially median, position between a first end and a second end of said suspension arm, • a suspension device comprising at least one suspension provided between the chassis of the vehicle and the second end of the suspension arm for suspending and damping vertical movements; these means being arranged so that when the control rod is pivoted by the control actuator, the wheel bearing shaft pivots with respect to the chassis about a vertical axis,
Brake system for a vehicle, comprising: a master brake cylinder; a brake circuit (14a, 14b) with two wheel brake callipers (16a, 16b), two wheel outlet valves (45a, 45b), an accumulator chamber (18a, 18b), a high-pressure switching valve (20a, 20b) and a pump (46a, 46b), wherein an intake side of the pump is hydraulically connected via a first branching line (48a, 48b) to the two wheel outlet valves (45a, 45b), and the high-pressure switching valve (20a, 20b) is hydraulically connected via a second line (70a, 70b) to a branching point (72a, 72b) which is formed in the first line (48a, 48b); and a control device having a valve control device which is configured to control, while taking into account a supplied information signal relating to a generator braking torque, which is currently applied or is to be applied, of a generator, the high-pressure switching valve (20a, 20b) into an at least partially opened state in such a way that a volume of brake fluid is shifted from the master brake cylinder into the accumulator chamber (18a, 18b) via the high-pressure switching valve (20a, 20b) which is controlled into the at least partially opened state, characterized in that the accumulator chamber (18a, 18b) is a low-pressure accumulator chamber (18a, 18b) which is connected to the first line (48a, 48b), which is without a non-return valve, in such a way that the volume of brake fluid is transferred into the low-pressure accumulator chamber (18a, 18b) by bypassing the two wheel brake callipers (16a, 16b). a master brake cylinder; a brake circuit (14a, 14b) with two wheel brake callipers (16a, 16b), two wheel outlet valves (45a, 45b), an accumulator chamber (18a, 18b), a high-pressure switching valve (20a, 20b) and a pump (46a, 46b), wherein an intake side of the pump is hydraulically connected via a first branching line (48a, 48b) to the two wheel outlet valves (45a, 45b), and the high-pressure switching valve (20a, 20b) is hydraulically connected via a second line (70a, 70b) to a branching point (72a, 72b) which is formed in the first line (48a, 48b); and a control device having a valve control device which is configured to control, while taking into account a supplied information signal relating to a generator braking torque, which is currently applied or is to be applied, of a generator, the high-pressure switching valve (20a, 20b) into an at least partially opened state in such a way that a volume of brake fluid is shifted from the master brake cylinder into the accumulator chamber (18a, 18b) via the high-pressure switching valve (20a, 20b) which is controlled into the at least partially opened state, characterized in that the accumulator chamber (18a, 18b) is a low-pressure accumulator chamber (18a, 18b) which is connected to the first line (48a, 48b), which is without a non-return valve, in such a way that the volume of brake fluid is transferred into the low-pressure accumulator chamber (18a, 18b) by bypassing the two wheel brake callipers (16a, 16b).
A compound of Formula I wherein, 'X' is selected from a group consisting of oxygen, sulphur, and selenium; 'R 1 ' is selected from a group consisting of alkyl chain, allyl group, aryl group, benzyl group, aryl and alky group, acid, amine, ester, methyl phenyl boronic acid, boronic ester,carbonate, phosphate, silane, quaternary ammonium, amide and, imine; 'R 2 ' is selected from a group consisting of H, OH, halogen, alkyl and wherein, the halogen is selected from a group consisting of bromide, chloride and iodide; 'R 3 ' or 'R 4 ' is selected from a group consisting of H, alkyl, aryl, nitrile, acid and halogen, and wherein the halogen is selected from a group consisting of chloride, fluoride, bromide and iodide; 'R 5 ', 'R 6 ', 'R 7 ' or 'R 8 ' is selected from a group consisting of H, OH, alkyl, aryl, halogen, nitro, sulfonates (SO 3 -) and nitrile group; 'R 9 ' is selected from a group consisting of H and -(CH 2) n -, wherein 'n' is 1-6; 'R 10 ' is selected from a group consisting of hydrogen, -OH, methyl, amine, terminal alkyne, alkene, alkyl acid, amine acid and sulfonates (SO 3 -); or its salt, tautomer, polymorph, or solvate thereof. 'X' is selected from a group consisting of oxygen, sulphur, and selenium; 'R 1 ' is selected from a group consisting of alkyl chain, allyl group, aryl group, benzyl group, aryl and alky group, acid, amine, ester, methyl phenyl boronic acid, boronic ester,carbonate, phosphate, silane, quaternary ammonium, amide and, imine; 'R 2 ' is selected from a group consisting of H, OH, halogen, alkyl and wherein, the halogen is selected from a group consisting of bromide, chloride and iodide; 'R 3 ' or 'R 4 ' is selected from a group consisting of H, alkyl, aryl, nitrile, acid and halogen, and wherein the halogen is selected from a group consisting of chloride, fluoride, bromide and iodide; 'R 5 ', 'R 6 ', 'R 7 ' or 'R 8 ' is selected from a group consisting of H, OH, alkyl, aryl, halogen, nitro, sulfonates (SO 3 -) and nitrile group; 'R 9 ' is selected from a group consisting of H and -(CH 2) n -, wherein 'n' is 1-6; 'R 10 ' is selected from a group consisting of hydrogen, -OH, methyl, amine, terminal alkyne, alkene, alkyl acid, amine acid and sulfonates (SO 3 -);
A method for manufacturing a silicon carbide semiconductor device comprising the steps in the following order: a first step of forming a thermal oxide film on one surface of an SiC substrate by thermal oxidation at a temperature of 1150°C or above in a gas atmosphere including molecules which contain nitrogen and oxygen, and introducing highly-concentrated nitrogen to said one surface of the SiC substrate in the course of forming the thermal oxide film; a second step of forming a highly-concentrated n-type SiC layer on said one surface of the SiC substrate such that the thermal oxide film is removed from said one surface of the SiC substrate by etching and, thereafter, said one surface of the SiC substrate is exposed to radicals so that Si-N bonded bodies and C-N bonded bodies which are formed on said one surface of the SiC substrate in the course of introducing highly-concentrated nitrogen into said one surface of the SiC substrate are removed while leaving nitrogen introduced into a lattice of SiC out of highly-concentrated nitrogen introduced into said one surface of the SiC substrate; and a third step of forming an ohmic electrode layer on said one surface of the SiC substrate. a first step of forming a thermal oxide film on one surface of an SiC substrate by thermal oxidation at a temperature of 1150°C or above in a gas atmosphere including molecules which contain nitrogen and oxygen, and introducing highly-concentrated nitrogen to said one surface of the SiC substrate in the course of forming the thermal oxide film; a second step of forming a highly-concentrated n-type SiC layer on said one surface of the SiC substrate such that the thermal oxide film is removed from said one surface of the SiC substrate by etching and, thereafter, said one surface of the SiC substrate is exposed to radicals so that Si-N bonded bodies and C-N bonded bodies which are formed on said one surface of the SiC substrate in the course of introducing highly-concentrated nitrogen into said one surface of the SiC substrate are removed while leaving nitrogen introduced into a lattice of SiC out of highly-concentrated nitrogen introduced into said one surface of the SiC substrate; and a third step of forming an ohmic electrode layer on said one surface of the SiC substrate.
Composition comprising difethialone, characterised in that it comprises a configurational stereoisomer of difethialone, referred to as a hetero-stereoisomer, of formula 3-(4'bromobiphenyl-4-yl)-1-(4-hydroxythiocoumarin-3-yl)-1,2,3,4-tetrahydronaphtalene, wherein the carbon atoms 1 and 3 of the 1,2,3,4-tetrahydronaphtalene group have different absolute configurations, said composition comprising an amount of a dextrorotatory enantiomer of said hetero-stereoisomer such that the ratio of this amount to the amount of difethialone in the composition is less than 10%; the amount of the dextrorotatory enantiomer of said hetero-stereoisomer of difethialone in the composition being different from the amount of levorotatory enantiomer of said hetero-stereoisomer of difethialone in the composition.