An ultrasound imaging system for inspecting an object in a volume, the ultrasound imaging system comprising: a transducer array configured to provide an ultrasound receive signal, a beam former configured to control the transducer array to scan the volume, and further configured to receive the ultrasound receive signal and to provide an image signal, a controller for controlling the beam former, a signal processor configured to receive the image signal and to provide three-dimensional image data and contrast-enhanced three-dimensional image data, and an image processor configured to receive image data and to provide display data, wherein the image processor is configured to receive three-dimensional ultrasound image data and contrast-enhanced three-dimensional ultrasound image data, and to conduct a segmentation of the object simultaneously out of the three-dimensional ultrasound image data and contrast-enhanced three-dimensional ultrasound image data, wherein the image processor is configured to conduct the segmentation by minimizing an energy term so that a deformed initial geometric shape substantially corresponds to the object's boundary, wherein the energy term comprises a first term representing the three-dimensional ultrasound image data and a second term representing the contrast-enhanced three-dimensional ultrasound image data, wherein the deformed initial geometric shape is the same in both the first and the second term, and wherein one of the first and second terms comprises a registering transformation registering the three-dimensional ultrasound image data and the contrast-enhanced three-dimensional ultrasound image data, characterized in that a deformation of the initial geometric shape is conducted by applying a global transformation and a non-rigid local transformation on the initial geometric shape, wherein the global transformation translates, rotates and scales the initial geometric shape, and wherein the non-rigid local transformation applies a displacement field having built-in smoothness on the initial geometric shape, and wherein the energy term further comprises a third term constraining the non-rigid local transformation. a transducer array configured to provide an ultrasound receive signal, a beam former configured to control the transducer array to scan the volume, and further configured to receive the ultrasound receive signal and to provide an image signal, a controller for controlling the beam former, a signal processor configured to receive the image signal and to provide three-dimensional image data and contrast-enhanced three-dimensional image data, and an image processor configured to receive image data and to provide display data, wherein the image processor is configured to receive three-dimensional ultrasound image data and contrast-enhanced three-dimensional ultrasound image data, and to conduct a segmentation of the object simultaneously out of the three-dimensional ultrasound image data and contrast-enhanced three-dimensional ultrasound image data, wherein the image processor is configured to conduct the segmentation by minimizing an energy term so that a deformed initial geometric shape substantially corresponds to the object's boundary, wherein the energy term comprises a first term representing the three-dimensional ultrasound image data and a second term representing the contrast-enhanced three-dimensional ultrasound image data, wherein the deformed initial geometric shape is the same in both the first and the second term, and wherein one of the first and second terms comprises a registering transformation registering the three-dimensional ultrasound image data and the contrast-enhanced three-dimensional ultrasound image data, characterized in that a deformation of the initial geometric shape is conducted by applying a global transformation and a non-rigid local transformation on the initial geometric shape, wherein the global transformation translates, rotates and scales the initial geometric shape, and wherein the non-rigid local transformation applies a displacement field having built-in smoothness on the initial geometric shape, and wherein the energy term further comprises a third term constraining the non-rigid local transformation.