A system for applying a superimposed time-varying frequency electromagnetic wave to a target object or a target region that is formed by the target object and a medium surrounding the target object, the system comprising: a device for generating the superimposed time-varying frequency electromagnetic wave, wherein the device comprises: at least two output terminals; an alternating current wave generator configured to generate an AC driving signal corresponding to an AC electromagnetic wave having a time-varying frequency at a desired sweeping time; and a direct current biasing unit electrically coupled in series with the AC wave generator, wherein the DC biasing unit is configured to produce a DC output with a predefined DC bias voltage, receive the AC driving signal, and mix the DC output with the received AC driving signal to produce the superimposed time-varying frequency electromagnetic wave where the time-varying frequency AC electromagnetic wave is riding on the predefined DC bias voltage, and an actuator provided at one or each of both of a first excitation site and a second excitation site of the target object or the target region and electrically coupled in series with the output terminal of the device, wherein the device is electrically coupled in series with the first excitation site and the second excitation site of the target object or the target region directly or through the actuator, and wherein the device is configured to superimpose the DC bias output and the AC driving signal to produce the superimposed time-varying frequency electromagnetic wave to be applied to the target object or the target region to induce a flow of ionic current having a DC component traveling in a pulsating and time-varying manner in the target object and/or in the medium and effect induced vibration of electrons and molecules of the target object and the medium. a device for generating the superimposed time-varying frequency electromagnetic wave, wherein the device comprises: at least two output terminals; an alternating current wave generator configured to generate an AC driving signal corresponding to an AC electromagnetic wave having a time-varying frequency at a desired sweeping time; and a direct current biasing unit electrically coupled in series with the AC wave generator, wherein the DC biasing unit is configured to produce a DC output with a predefined DC bias voltage, receive the AC driving signal, and mix the DC output with the received AC driving signal to produce the superimposed time-varying frequency electromagnetic wave where the time-varying frequency AC electromagnetic wave is riding on the predefined DC bias voltage, and at least two output terminals; an alternating current wave generator configured to generate an AC driving signal corresponding to an AC electromagnetic wave having a time-varying frequency at a desired sweeping time; and a direct current biasing unit electrically coupled in series with the AC wave generator, wherein the DC biasing unit is configured to produce a DC output with a predefined DC bias voltage, receive the AC driving signal, and mix the DC output with the received AC driving signal to produce the superimposed time-varying frequency electromagnetic wave where the time-varying frequency AC electromagnetic wave is riding on the predefined DC bias voltage, and an actuator provided at one or each of both of a first excitation site and a second excitation site of the target object or the target region and electrically coupled in series with the output terminal of the device, wherein the device is electrically coupled in series with the first excitation site and the second excitation site of the target object or the target region directly or through the actuator, and wherein the device is configured to superimpose the DC bias output and the AC driving signal to produce the superimposed time-varying frequency electromagnetic wave to be applied to the target object or the target region to induce a flow of ionic current having a DC component traveling in a pulsating and time-varying manner in the target object and/or in the medium and effect induced vibration of electrons and molecules of the target object and the medium.