mhurhangee/ep-ind-claims huggingface dataset:
A method for analyzing a sample, comprising the steps of: (a). contacting a sample with a set of peptide constructs, wherein each peptide construct of the set comprises a peptide portion and an identifying nucleic acid portion, wherein the peptide portions are encoded by the oligonucleotide sequences that are custom-designed so that at least 10% of the set of peptide constructs produced contain contiguous peptide sequences of at least 12 amino acids that have more than 80% amino acid sequence identity to protein sequences encoded by one or more organisms; and wherein at least one of the peptide constructs is acted upon by an agent in the sample; (b). separating the at least one peptide construct that is acted upon by the agent from peptide constructs that are not acted upon by the agent; and (c). analyzing the identifying nucleic acid portion of a peptide construct separated in step (b), thereby identifying the at least one peptide construct that is acted upon by the agent in the sample. (a). contacting a sample with a set of peptide constructs, wherein each peptide construct of the set comprises a peptide portion and an identifying nucleic acid portion, wherein the peptide portions are encoded by the oligonucleotide sequences that are custom-designed so that at least 10% of the set of peptide constructs produced contain contiguous peptide sequences of at least 12 amino acids that have more than 80% amino acid sequence identity to protein sequences encoded by one or more organisms; and wherein at least one of the peptide constructs is acted upon by an agent in the sample; (b). separating the at least one peptide construct that is acted upon by the agent from peptide constructs that are not acted upon by the agent; and (c). analyzing the identifying nucleic acid portion of a peptide construct separated in step (b), thereby identifying the at least one peptide construct that is acted upon by the agent in the sample.
A method of establishing a media streaming connection between a media player and a placeshifting device, separated by a firewall, that are each communicating via a network, the placeshifting device allowing remote viewing of television or other media content at locations other than the viewer's primary television set, the method comprising: receiving, at a relay server, a first request associated with the media player and a second request associated with the placeshifting device; in response to receiving the first and second requests, establishing a first connection between the relay server and the media player and a second connection between the relay server and the placeshifting device; and relaying data received by the relay server on each of the first and second connections to the other of the first and second connections to thereby establish the media streaming connection between the media player and the placeshifting device via the relay server; characterised in that a message server is configured to establish a pre-existing connection with the placeshifting device across the network using a connection-based protocol, the method further comprising sending a message to the placeshifting device across the pre-existing connection to direct the placeshifting device to establish the second connection with the relay server. receiving, at a relay server, a first request associated with the media player and a second request associated with the placeshifting device; in response to receiving the first and second requests, establishing a first connection between the relay server and the media player and a second connection between the relay server and the placeshifting device; and relaying data received by the relay server on each of the first and second connections to the other of the first and second connections to thereby establish the media streaming connection between the media player and the placeshifting device via the relay server; characterised in that a message server is configured to establish a pre-existing connection with the placeshifting device across the network using a connection-based protocol, the method further comprising sending a message to the placeshifting device across the pre-existing connection to direct the placeshifting device to establish the second connection with the relay server.
A liquid applicator for applying a liquid to a surface, the applicator comprising: an elongated hollow body comprising a wall defining an internal chamber having a closed end and an open end; wherein the wall comprises a handle region and a crush region and wherein the ratio of thickness of the wall in the crush region over the thickness of the wall in the handle region is less than 1; a first ampoule formed of a frangible material located in the internal chamber proximate the crush region and containing the liquid; a lever integral with the hollow body and comprising a hinge projecting from a first location attached to the hollow body to a second location, a grip extending from the second location to a third location, and a foot integral to the wall adjacent the crush region; wherein the lever comprises a first truss extending from the third location to the foot; a third truss extending from the second location to the foot, and a second truss between the first and third trusses (151, 155) and extending from the foot to a fourth location, between the second and third location (144, 146); wherein the width of the first truss is tapered from a first width proximate the third location and a second width proximate the foot; wherein the ratio of the second width over the first width is less than 1. an elongated hollow body comprising a wall defining an internal chamber having a closed end and an open end; wherein the wall comprises a handle region and a crush region and wherein the ratio of thickness of the wall in the crush region over the thickness of the wall in the handle region is less than 1; a first ampoule formed of a frangible material located in the internal chamber proximate the crush region and containing the liquid; a lever integral with the hollow body and comprising a hinge projecting from a first location attached to the hollow body to a second location, a grip extending from the second location to a third location, and a foot integral to the wall adjacent the crush region; wherein the lever comprises a first truss extending from the third location to the foot; a third truss extending from the second location to the foot, and a second truss between the first and third trusses (151, 155) and extending from the foot to a fourth location, between the second and third location (144, 146); wherein the width of the first truss is tapered from a first width proximate the third location and a second width proximate the foot; wherein the ratio of the second width over the first width is less than 1.
A peptide, which derives from the human dermcidin amino acid sequence, according to the following consecutive sequence of formula or S-S-L-L-X1-K-G-L-X2-X3-X4-X5-X6-X7 or S - S - L - L - X1 - K - Z1 retro-, inverso- and retroinverso-form or pharmaceutically acceptable salts or solvates thereof, wherein X1 is any L- or D-amino acid; X2 is any L- or D-amino acid or is absent; X3 is any L- or D-amino acid or is absent; X4 is absent or an amino acid sequence comprising from 1 to 10 amino acids of the consecutive amino acid sequence A-Y1-Y2-A-V-G-G-L-G-Y3, wherein Y1, Y2 and Y3 are any L- or D-amino acid; X5 is absent or an amino acid sequence comprising from 1 to 10 amino acids of the consecutive amino acid sequence L-G-Y4-Y5-A-V-E-D-L-E, wherein Y4 and Y5 are any L- or D-amino acid; X6 is absent or an amino acid sequence comprising from 1 to 10 amino acids of the consecutive amino acid sequence S-V-G-K-G-A-V-H-D-V; X7 is absent or an amino acid sequence comprising from 1 to 8 amino acids of the consecutive amino acid sequence K-D-V-L-D-S-V-L; wherein in the case that one of X2 to X6 is absent the subsequent amino acids X3 to X7 are also absent; Z1 is G or g or is absent; wherein capital letters represent L-amino acids and small letters represent D-amino acids and wherein one or more L-amino acids in the formula or may be replaced by its corresponding D-form; for the use as a cell-penetrating agent as a medicament, in therapy and in vivo diagnostics. X1 is any L- or D-amino acid; X2 is any L- or D-amino acid or is absent; X3 is any L- or D-amino acid or is absent; X4 is absent or an amino acid sequence comprising from 1 to 10 amino acids of the consecutive amino acid sequence A-Y1-Y2-A-V-G-G-L-G-Y3, wherein Y1, Y2 and Y3 are any L- or D-amino acid; X5 is absent or an amino acid sequence comprising from 1 to 10 amino acids of the consecutive amino acid sequence L-G-Y4-Y5-A-V-E-D-L-E, wherein Y4 and Y5 are any L- or D-amino acid; X6 is absent or an amino acid sequence comprising from 1 to 10 amino acids of the consecutive amino acid sequence S-V-G-K-G-A-V-H-D-V; X7 is absent or an amino acid sequence comprising from 1 to 8 amino acids of the consecutive amino acid sequence K-D-V-L-D-S-V-L; Z1 is G or g or is absent; wherein capital letters represent L-amino acids and small letters represent D-amino acids and wherein one or more L-amino acids in the formula or may be replaced by its corresponding D-form; for the use as a cell-penetrating agent as a medicament, in therapy and in vivo diagnostics.
A radial foil bearing comprising: a bearing housing which has an insertion hole through which a shaft is inserted; a back foil which is disposed on an inner peripheral surface of the insertion hole; and an engagement member which includes a first part and a second part, the first part being disposed to overlap the back foil in a radial direction of the insertion hole and engaged with the back foil, and the second part being attached to the bearing housing, wherein the first part has an engagement groove which extends to an end edge of the first part in an axial direction of the insertion hole, the back foil is disposed in the engagement groove, and the back foil has crest portions and trough portions which are alternately formed in a circumferential direction of the inner peripheral surface of the insertion hole, characterized in that the first part has a first claw portion and a second claw portion provided on opposing sides of the engagement groove with respect to each other, the first claw portion being disposed inside the trough portion in the radial direction, and the second claw portion being disposed outside the crest portion in the radial direction. a bearing housing which has an insertion hole through which a shaft is inserted; a back foil which is disposed on an inner peripheral surface of the insertion hole; and an engagement member which includes a first part and a second part, the first part being disposed to overlap the back foil in a radial direction of the insertion hole and engaged with the back foil, and the second part being attached to the bearing housing, wherein the first part has an engagement groove which extends to an end edge of the first part in an axial direction of the insertion hole, the back foil is disposed in the engagement groove, and the back foil has crest portions and trough portions which are alternately formed in a circumferential direction of the inner peripheral surface of the insertion hole, characterized in that the first part has a first claw portion and a second claw portion provided on opposing sides of the engagement groove with respect to each other, the first claw portion being disposed inside the trough portion in the radial direction, and the second claw portion being disposed outside the crest portion in the radial direction.
A user equipment, UE, for channel estimation in a wireless communications network system, said UE comprising a receiver circuit configured to receive a plurality of consecutive physical resource blocks from a radio base station; the UE characterized in that it further comprises: - a channel estimator configured to estimate a channel coefficient of each received physical resource block; - a calculator circuit configured to calculate for each two adjacent physical resource blocks, a difference between estimated channel coefficients of the two adjacent physical resource blocks; - a comparator circuit configured to compare each calculated difference with a predefined threshold value; - an assembler circuit configured to group physical resource blocks for which said calculated difference is less than or equal to the predefined threshold value; - wherein the channel estimator is further configured to perform a group-wise channel estimation on a group comprising physical resource blocks for which said calculated difference is less than or equal to the predefined threshold and to further perform per physical resource block channel estimation on each remaining physical resource block. - a channel estimator configured to estimate a channel coefficient of each received physical resource block; - a calculator circuit configured to calculate for each two adjacent physical resource blocks, a difference between estimated channel coefficients of the two adjacent physical resource blocks; - a comparator circuit configured to compare each calculated difference with a predefined threshold value; - an assembler circuit configured to group physical resource blocks for which said calculated difference is less than or equal to the predefined threshold value; - wherein the channel estimator is further configured to perform a group-wise channel estimation on a group comprising physical resource blocks for which said calculated difference is less than or equal to the predefined threshold and to further perform per physical resource block channel estimation on each remaining physical resource block.
Venetian blind with an installation device, having: 1.1. two basic rails, which, for the purpose of installing the venetian blind, are fastened on a fastening base with force-fitting action and parallel orientation, 1.2. a preassembled system unit, which is designed, for installation purpose, such that it can be plugged onto the basic rails, wherein the system unit comprises a cover panel, two laterally arranged plug-in holders, a venetian-blind body, comprising a multiplicity of slats having guide pins at their longitudinal ends, and a drive system, having at least one gear mechanism and at least two winding-up devices (8.1), 1.3. two body-guide rails, in which the guide pins of the slats can engage and which, for installation purposes, are fastened on the basic rails. 1.1. two basic rails, which, for the purpose of installing the venetian blind, are fastened on a fastening base with force-fitting action and parallel orientation, 1.2. a preassembled system unit, which is designed, for installation purpose, such that it can be plugged onto the basic rails, wherein the system unit comprises a cover panel, two laterally arranged plug-in holders, a venetian-blind body, comprising a multiplicity of slats having guide pins at their longitudinal ends, and a drive system, having at least one gear mechanism and at least two winding-up devices (8.1), 1.3. two body-guide rails, in which the guide pins of the slats can engage and which, for installation purposes, are fastened on the basic rails.
An engine comprising: a cool liquid cooler that cools a first cool liquid that cools an engine block including a cylinder block and a head block; and a lubricant oil cooler that cools a lubricant oil using the first cool liquid or a second cool liquid, wherein the cool liquid cooler and the lubricant oil cooler are so placed as to be arranged side by side on one end side in a crankshaft direction, characterized in that the engine further includes a gear case placed between the engine block and the cool liquid cooler, and/or between the engine block and the lubricant oil cooler, wherein the cool liquid cooler and/or the lubricant oil cooler is mounted to the gear case. a cool liquid cooler that cools a first cool liquid that cools an engine block including a cylinder block and a head block; and a lubricant oil cooler that cools a lubricant oil using the first cool liquid or a second cool liquid, the cool liquid cooler and the lubricant oil cooler are so placed as to be arranged side by side on one end side in a crankshaft direction, characterized in that the engine further includes a gear case placed between the engine block and the cool liquid cooler, and/or between the engine block and the lubricant oil cooler, wherein the cool liquid cooler and/or the lubricant oil cooler is mounted to the gear case. a gear case placed between the engine block and the cool liquid cooler, and/or between the engine block and the lubricant oil cooler, wherein the cool liquid cooler and/or the lubricant oil cooler is mounted to the gear case.
Checking method for a parking system which comprises a car park with a plurality of parking spaces for parking motor vehicles, wherein in the car park a motor vehicle can be controlled autonomously on a route between a parking area and one of the parking spaces, and the method is characterized by the following steps: - autonomous driving along the route with a test vehicle; - determining that the travel along the route takes place correctly; and - enabling the parking system for use with vehicles which correspond to the vehicle type of the test vehicle. - autonomous driving along the route with a test vehicle; - determining that the travel along the route takes place correctly; and - enabling the parking system for use with vehicles which correspond to the vehicle type of the test vehicle.
A system for inducing sonoporation of a drug into cancer cells in a tumor, comprising: - a generator configured to provide electrical energy at an ultrasound frequency; - at least one ultrasound probe electrically connected to the generator and configured to convert the electrical energy into low intensity non-focalized pulsed ultrasonic waves defined by operation parameters, said operation parameters comprising the frequency of the ultrasonic waves; - an input device enabling an operator to enter configuration data comprising type of drug; and - a processor configured to: determine the values of said operation parameters on the basis of the entered configuration data; and control the generator and the ultrasound probe to operate according to said determined values; characterized in that the operation parameters further comprise the duty cycle of the ultrasonic waves, the input device is further enabling an operator to enter configuration data comprising type of tumor, and the processor is configured to determine the value of the frequency on the basis of at least the type of tumor, and the value of the duty cycle on the basis of at least the type of drug and the type of tumor. - a generator configured to provide electrical energy at an ultrasound frequency; - at least one ultrasound probe electrically connected to the generator and configured to convert the electrical energy into low intensity non-focalized pulsed ultrasonic waves defined by operation parameters, said operation parameters comprising the frequency of the ultrasonic waves; - an input device enabling an operator to enter configuration data comprising type of drug; and - a processor configured to: determine the values of said operation parameters on the basis of the entered configuration data; and control the generator and the ultrasound probe to operate according to said determined values; characterized in that the operation parameters further comprise the duty cycle of the ultrasonic waves, the input device is further enabling an operator to enter configuration data comprising type of tumor, and the processor is configured to determine the value of the frequency on the basis of at least the type of tumor, and the value of the duty cycle on the basis of at least the type of drug and the type of tumor. determine the values of said operation parameters on the basis of the entered configuration data; and control the generator and the ultrasound probe to operate according to said determined values;
A method for preventing and/or extinguishing a fire in an enclosed target area in a vehicle, particularly in a railway vehicle, wherein the vehicle comprises a central compressed air source for supplying compressed air as needed to a load circuit, and wherein the method comprises the following method steps: - providing a supply of compressed air in a compressed air buffer tank; - supplying compressed air from the compressed air buffer tank to a gas separation device as needed; - performing a gas separation in the gas separation device and providing a nitrogen-enriched gas mixture at an outlet of the gas separation device; and - introducing the nitrogen-enriched gas mixture into the target area as needed, characterized in that in order to provide the supply of compressed air, an inlet of the compressed air buffer tank is at least intermittently fluidly connected to an outlet of a central compressed air source such that compressed air can be supplied to the compressed air buffer tank, wherein a fluid connection between the central compressed air source and the compressed air buffer tank is provided when the load circuit is not drawing any compressed air from the central compressed air source. - providing a supply of compressed air in a compressed air buffer tank; - supplying compressed air from the compressed air buffer tank to a gas separation device as needed; - performing a gas separation in the gas separation device and providing a nitrogen-enriched gas mixture at an outlet of the gas separation device; and - introducing the nitrogen-enriched gas mixture into the target area as needed,
Apparatus for cleaning contaminated aggregate comprising: at least one channel arranged in use to receive a liquid containing contaminated aggregate, the channel having a base comprising agitators spaced along the length of the channel; and first and second banks or groups of at least one jet; in which the first bank or group of jets are spaced along the length of the channel and arranged to direct pressurised fluid at the contaminated aggregate in order to force the contaminated aggregate against and over the agitators along the length of the channel to a first outlet thereby agitating the aggregate and promoting separation of aggregate from debris; and in which the second bank or group of jets is arranged to direct and/or urge debris to a second outlet.
A kit useful for determining the phage susceptibility of one or more strains of Lactococcus lactis by means of polymerase chain reaction, ideally multiplex PCR, comprising: (a) a first primer pair adapted to generate a first amplicon from a region of the cwps operon that is unique to L. lactis strains MG1363 and SK11; (b) a second primer pair adapted to generate a second amplicon from a region of the cwps operon that is unique to L. lactis strains IL1403 and KF147; (c) a third primer pair adapted to generate a third amplicon from a region of the cwps operon that is unique to L. lactis strains UC509.9 and CV56; and (d) optionally, a control primer pair adapted to amplify a sequence conserved in strains of L.lactis. (a) a first primer pair adapted to generate a first amplicon from a region of the cwps operon that is unique to L. lactis strains MG1363 and SK11; (b) a second primer pair adapted to generate a second amplicon from a region of the cwps operon that is unique to L. lactis strains IL1403 and KF147; (c) a third primer pair adapted to generate a third amplicon from a region of the cwps operon that is unique to L. lactis strains UC509.9 and CV56; and (d) optionally, a control primer pair adapted to amplify a sequence conserved in strains of L.lactis.