A compound of Formula or its stereoisomers or tautomers, or pharmaceutically acceptable salts of each of the foregoing, including mixtures thereof in all ratios, wherein R 1', R 1" are independently H, A, Hal, Cyc, CO(Cyc), R 2 is H, Q 1 -(C H) n -Q 2, R 3 is H, A, -LA-Cyc A is unbranched or branched linear or cyclic alkyl having 1, 2, 3, 4 or 5 C atoms, in which one CH 2 group may be replaced by an O or S atom and/or by an -NH-, -CO-, -NHCOO-, -NHCONH-, -CONH-, -NHCO-, -CH=CH-, -N=CH- or -CH=N- group, and in which 1-5 H atoms may be replaced by Hal, and in which one CH group may be replaced by N, and in which one CH 3 group may be replaced by CN, Hal is F, Cl, Br or I, Cyc is a monocyclic, non-aromatic or aromatic, homo- or heterocycle having 0, 1 or 2, N, O and/or S atoms and 4, 5 or 6 skeleton atoms, which may be unsubstituted or, independently of one another, mono- or disubstituted by Hal, LA, OH, carbonyl oxygen, SH, O, NH 2, NH, N 2, NO 2, CN, OCN, SCN, COOH, COO, CONH 2, CONH, CON 2, NHCO, NHCONH, NHCONH 2, NHSO 2, CHO, CO, SO 2 NH 2, SO 2 and/or SO 2 Hal, Q 1 -NH-, -O-, -COO-, -CONH-, or a bond, Q 2 NH 2, NH, N 2, CONH 2, CONH, CON 2, COOH, COO, Cyc, CO(Cyc), n 0, 1, 2, 3 or 4, Ar is a mono- or bicyclic aromatic homo- or heterocycle having 0, 1, 2, 3 or 4 N, O and/or S atoms and 5, 6, 7, 8, 9, or 10 skeleton atoms, which may be unsubstituted or, independently of one another, mono-, di- or trisubstituted by Hal, A, OH, SH, OA, NH 2, NHA, NA 2, NO 2, CN, OCN, SCN, COOH, CONH 2, CONHA, CONA 2, NHCOA, NHCONHA, NHCONH 2, NHSO 2 A, CHO, COA, SO 2 NH 2, SO 2 A, SO 2 HaI and/or m-Cyc, and in which a ring N-atom may be substituted by an O-atom to form an N-oxide group, and in which in the case of a bicyclic ring system one ring may be aromatic, and the other ring non-aromatic, X CH 2, NH, O, W, Y, Z are CH or N, wherein at least two of W, Y, Z are CH, m 0 or 1, and LA is H, or unbranched or branched, linear alkyl having 1, 2 or 3 or 4 C atoms, wherein 1, 2 or 3 H atoms may be replaced by Hal, provided that the compound is not (5-Methyl-pyrimidin-2-ylmethyl)-(6-phenyl-2-pyridin-3-yl-pyrimidin-4-yl)-amine. R 1', R 1" are independently H, A, Hal, Cyc, CO(Cyc), R 2 is H, Q 1 -(C H) n -Q 2, R 3 is H, A, -LA-Cyc A is unbranched or branched linear or cyclic alkyl having 1, 2, 3, 4 or 5 C atoms, in which one CH 2 group may be replaced by an O or S atom and/or by an -NH-, -CO-, -NHCOO-, -NHCONH-, -CONH-, -NHCO-, -CH=CH-, -N=CH- or -CH=N- group, and in which 1-5 H atoms may be replaced by Hal, and in which one CH group may be replaced by N, and in which one CH 3 group may be replaced by CN, Hal is F, Cl, Br or I, Cyc is a monocyclic, non-aromatic or aromatic, homo- or heterocycle having 0, 1 or 2, N, O and/or S atoms and 4, 5 or 6 skeleton atoms, which may be unsubstituted or, independently of one another, mono- or disubstituted by Hal, LA, OH, carbonyl oxygen, SH, O, NH 2, NH, N 2, NO 2, CN, OCN, SCN, COOH, COO, CONH 2, CONH, CON 2, NHCO, NHCONH, NHCONH 2, NHSO 2, CHO, CO, SO 2 NH 2, SO 2 and/or SO 2 Hal, Q 1 -NH-, -O-, -COO-, -CONH-, or a bond, Q 2 NH 2, NH, N 2, CONH 2, CONH, CON 2, COOH, COO, Cyc, CO(Cyc), n 0, 1, 2, 3 or 4, X CH 2, NH, O, W, Y, Z are CH or N, wherein at least two of W, Y, Z are CH, m 0 or 1, and LA is H, or unbranched or branched, linear alkyl having 1, 2 or 3 or 4 C atoms, wherein 1, 2 or 3 H atoms may be replaced by Hal,