A closure device (31,43) for closing a puncture wound, the device (31,43) deliverable in a delivery sheath (72,118,160) comprising a plunger (88, 132), the puncture wound having a length along a tissue tract (80,120) that resolves in an interior opening of a vessel or cavity (82,122), the closure device (31,43) comprising: (a) a distal section (2,50,110) placeable inside the interior opening of the vessel or cavity, the distal section (2,50,110) lodgable in a delivery sheath (72,118,160) having proximal and distal ends, the delivery sheath (72,118,160) capable of penetrating the wound along the length of the wound to pass through the interior opening and release the distal section (2,50,110), the released distal section (2,50,110) capable of rotation of about 90 degrees to provide resistance against the interior opening; (b) a proximal section (4,54,114) connected to the distal section (2,50,110), the proximal section (4,54,114) comprising a bunchable material capable of bunching in the tissue tract (80,120) upon deployment, the proximal section (4,54,114) releasable from the delivery sheath (72,118,160) in an unbunched state, bunchable upon release; (c) a first tension member (26,56,124) connected to the distal section (2,50,110) and extending through the proximal section (4,54,114), the first tension member (26, 56,124) configured for rotating the distal section (2,50,110) 90 degrees in the interior opening inside the vessel or cavity (82,122); and (d) a second tension member (28,58,126) connected to the proximal section (4,54,114) and configured for bunching the proximal section (4,54,114) upon release of the proximal section (4,54,114) in the tissue tract (80, 120); wherein first and second tension members (26, 56, 124, 28, 58, 126) are arranged such that upon use of the closure device (431, 43) the practioner is allowed to first position the distal section (2,50,110), wherein said positioning comprises rotating the distal section 90 degrees in the interior opening inside the vessel or cavity (82,122) while pulling the first tension member (26, 56,124) and at the same time using the plunger (88, 132) in the delivery sheath to push the proximal section (4, 54, 114) distally, and then the bunching of the proximal section (4,54,114) by pulling the second tension member (28, 58,126) while pushing the plunger (88, 132) upon release of the proximal section (4,54,114) in the tissue tract (80,120), thereby closing the puncture wound with the distal section (2,50,110) rotated 90 degrees inside the vessel or cavity (82,122) and the proximal section (4,54,114) bunched in the tissue tract (80,120). (a) a distal section (2,50,110) placeable inside the interior opening of the vessel or cavity, the distal section (2,50,110) lodgable in a delivery sheath (72,118,160) having proximal and distal ends, the delivery sheath (72,118,160) capable of penetrating the wound along the length of the wound to pass through the interior opening and release the distal section (2,50,110), the released distal section (2,50,110) capable of rotation of about 90 degrees to provide resistance against the interior opening; (b) a proximal section (4,54,114) connected to the distal section (2,50,110), the proximal section (4,54,114) comprising a bunchable material capable of bunching in the tissue tract (80,120) upon deployment, the proximal section (4,54,114) releasable from the delivery sheath (72,118,160) in an unbunched state, bunchable upon release; (c) a first tension member (26,56,124) connected to the distal section (2,50,110) and extending through the proximal section (4,54,114), the first tension member (26, 56,124) configured for rotating the distal section (2,50,110) 90 degrees in the interior opening inside the vessel or cavity (82,122); and (d) a second tension member (28,58,126) connected to the proximal section (4,54,114) and configured for bunching the proximal section (4,54,114) upon release of the proximal section (4,54,114) in the tissue tract (80, 120); wherein first and second tension members (26, 56, 124, 28, 58, 126) are arranged such that upon use of the closure device (431, 43) the practioner is allowed to first position the distal section (2,50,110), wherein said positioning comprises rotating the distal section 90 degrees in the interior opening inside the vessel or cavity (82,122) while pulling the first tension member (26, 56,124) and at the same time using the plunger (88, 132) in the delivery sheath to push the proximal section (4, 54, 114) distally, and then the bunching of the proximal section (4,54,114) by pulling the second tension member (28, 58,126) while pushing the plunger (88, 132) upon release of the proximal section (4,54,114) in the tissue tract (80,120), thereby closing the puncture wound with the distal section (2,50,110) rotated 90 degrees inside the vessel or cavity (82,122) and the proximal section (4,54,114) bunched in the tissue tract (80,120).