mhurhangee/ep-ind-claims huggingface dataset:
An isolated, therapeutic human antibody or antigen-binding portion thereof, comprising a heavy chain variable region (V H) according to SEQ ID NO: 12, and a light chain variable region (V L) according to i) SEQ ID NO: 53, ii) SEQ ID NO: 35, or (iii) SEQ ID NO: 25, and wherein said antibody or antigen-binding portion thereof specifically binds to homodimeric IL-17A and heterodimeric IL-17AF, but does not specifically bind to homodimeric IL-17F.
An analogue scanning probe comprising: a connector detachably connectable to a movable support of a coordinate measuring system; a swing arm support; a swing arm pivotally connected, by means of an articulation, to the swing arm support about a measure axis; a touch at the tip of the swing arm; one articulation comprised between said connector and said measure axis; wherein said one articulation is rotational mounted on the connector so to allow tilting of said swing arm with respect to the connector; and a position encoder delivering a measure of a tilt angle of said touch about said measure axis; characterized by a safety articulation that allows tilting of the stylus about a safety axis when the force exerted on the touch exceeds a determined limit, the safety axis lying in a plane not comprising the measure axis or the safety axis being orthogonal to the measure axis; and characterized in that the connector comprises several positioning surfaces arranged in order to provide an isostatic connection with six independent points of contact of the probe. a connector detachably connectable to a movable support of a coordinate measuring system; a swing arm support; a swing arm pivotally connected, by means of an articulation, to the swing arm support about a measure axis; a touch at the tip of the swing arm; one articulation comprised between said connector and said measure axis; wherein said one articulation is rotational mounted on the connector so to allow tilting of said swing arm with respect to the connector; and a position encoder delivering a measure of a tilt angle of said touch about said measure axis; characterized by a safety articulation that allows tilting of the stylus about a safety axis when the force exerted on the touch exceeds a determined limit, the safety axis lying in a plane not comprising the measure axis or the safety axis being orthogonal to the measure axis; and characterized in that the connector comprises several positioning surfaces arranged in order to provide an isostatic connection with six independent points of contact of the probe.
An all-solid state secondary cell comprising a positive electrode collector, a negative electrode collector, and a powder laminate disposed between the positive electrode collector and the negative electrode collector, wherein the powder laminate has a positive electrode powder layer and a negative electrode powder layer, and a solid electrolyte layer (23, 24) disposed between the positive electrode powder layer and the negative electrode powder layer, the solid electrolyte layer (23, 24) covering outer peripheries of the positive electrode powder layer and the negative electrode powder layer; the powder laminate comprises a peripheral edge part and a center part surrounded by the peripheral edge part; and characterized in that a thickness of the peripheral edge part is greater than a thickness of the center part. wherein the powder laminate has a positive electrode powder layer and a negative electrode powder layer, and a solid electrolyte layer (23, 24) disposed between the positive electrode powder layer and the negative electrode powder layer, the solid electrolyte layer (23, 24) covering outer peripheries of the positive electrode powder layer and the negative electrode powder layer; the powder laminate comprises a peripheral edge part and a center part surrounded by the peripheral edge part; and characterized in that a thickness of the peripheral edge part is greater than a thickness of the center part.
A method for controlling a woodburning stove of the type having a combustion chamber with a glass door, the combustion chamber having a walling (5, 8, 21, 22, 30) at the rear and at both side and downwards being separated from an ash chamber by means of a grate bottom, and connected with a chimney via a flue gas exhaust in which the flue gas temperature is detected by means of a thermal sensor, by which method primary combustion air is supplied to the combustion chamber via the ash chamber up through the grate bottom, and secondary combustion air is supplied directly to the combustion chamber, by which method is applied an electronic control which is connected with the thermal sensor and with a λ-probe provided in the flue gas exhaust, and tertiary combustion air is supplied directly to the combustion chamber via a feed opening along a top side of the door, and supply of primary, secondary and tertiary combustion (19, 33, 45) air to the combustion chamber is controlled by the electronic control by means of separate control valves (34, 40, 42), wherein the method comprises the steps of: - when firing a new portion of fuel, a primary valve is opened such that primary combustion air is supplied via the ash chamber up through the grate bottom, while a secondary valve is closed, - when reaching a temperature in the fire core of the magnitude 1000°-1200°C after some time, the primary valve is partially closed, while the secondary valve is partly opened and a tertiary valve is partly opened, controlled by a flue gas temperature of 200°-350°C and by the oxygen content in the flue gas which is detected by the λ-probe. - when firing a new portion of fuel, a primary valve is opened such that primary combustion air is supplied via the ash chamber up through the grate bottom, while a secondary valve is closed, - when reaching a temperature in the fire core of the magnitude 1000°-1200°C after some time, the primary valve is partially closed, while the secondary valve is partly opened and a tertiary valve is partly opened, controlled by a flue gas temperature of 200°-350°C and by the oxygen content in the flue gas which is detected by the λ-probe.
An articulating surgical instrument, the instrument comprising: a shaft defining a longitudinal axis (A-A); and an end effector pivotally coupled to said shaft for selective pivotal travel about an articulation axis substantially transverse to said longitudinal axis (A-A); characterised in that the instrument further comprises: a nozzle assembly comprising: a first nozzle segment movably supported on said shaft; and a second nozzle segment movably coupled to said first nozzle segment and movably supported on said shaft such that said first and second nozzle segments (412, 430) may be selectively moved on said shaft relative to each other and wherein said articulating surgical instrument further comprises: an articulation assembly operably interfacing with said end effector and said first and second nozzle segments (412, 430) such that movement of said first nozzle segment in a first axial direction causes said articulation assembly to apply a first articulation motion to said end effector and movement of said second nozzle segment in a second axial direction causes said articulation assembly to apply a second articulation motion to said end effector. a shaft defining a longitudinal axis (A-A); and an end effector pivotally coupled to said shaft for selective pivotal travel about an articulation axis substantially transverse to said longitudinal axis (A-A); a first nozzle segment movably supported on said shaft; and a second nozzle segment movably coupled to said first nozzle segment and movably supported on said shaft such that said first and second nozzle segments (412, 430) may be selectively moved on said shaft relative to each other and wherein said articulating surgical instrument further comprises: an articulation assembly operably interfacing with said end effector and said first and second nozzle segments (412, 430) such that movement of said first nozzle segment in a first axial direction causes said articulation assembly to apply a first articulation motion to said end effector and movement of said second nozzle segment in a second axial direction causes said articulation assembly to apply a second articulation motion to said end effector.
A testing device for detecting a colour-change result of a lateral flow test arranged to detect the presence of a target substance in a liquid sample, the testing device comprising: one or more receptacles for receiving one or more lateral flow tests; one or more sensor systems for detecting results provided by the one or more lateral flow tests; a microcontroller connected to the one or more sensor systems for processing data from the one or more sensor systems; and a wireless transmitter connected to the microcontroller arranged as a transponder with respect to an initiator device that provides an electromagnetic field which the transponder modulates, wherein the wireless transmitter is arranged to use a Near-Field Communication, NFC, communication protocol, such that the testing device draws its operating power from the electromagnetic field provided by the initiator device. one or more receptacles for receiving one or more lateral flow tests; one or more sensor systems for detecting results provided by the one or more lateral flow tests; a microcontroller connected to the one or more sensor systems for processing data from the one or more sensor systems; and a wireless transmitter connected to the microcontroller arranged as a transponder with respect to an initiator device that provides an electromagnetic field which the transponder modulates, wherein the wireless transmitter is arranged to use a Near-Field Communication, NFC, communication protocol, such that the testing device draws its operating power from the electromagnetic field provided by the initiator device.
An optical device comprising: a layer of material in the solid state that modifies the reflectivity of the device in such a way as to provide a pattern comprising a recognizable image; and a reflector, characterized in that: said material is a phase change material having a refractive index that is switchable between at least two stable values, and the pattern is defined by setting of the refractive index of different regions in the layer of material by switching of the phase change material in the different regions; and wherein the reflector is spaced apart from the layer of material by a solid spacer layer transmissive to light. a layer of material in the solid state that modifies the reflectivity of the device in such a way as to provide a pattern comprising a recognizable image; and a reflector, characterized in that: said material is a phase change material having a refractive index that is switchable between at least two stable values, and the pattern is defined by setting of the refractive index of different regions in the layer of material by switching of the phase change material in the different regions; and wherein the reflector is spaced apart from the layer of material by a solid spacer layer transmissive to light. said material is a phase change material having a refractive index that is switchable between at least two stable values, and the pattern is defined by setting of the refractive index of different regions in the layer of material by switching of the phase change material in the different regions; and wherein the reflector is spaced apart from the layer of material by a solid spacer layer transmissive to light.
A method for gaining access to a communication medium in a contention-based network, said method comprising: receiving a slot count based on a number of stations in said contention-based network; adjusting said slot count and adopting a round robin service; initiating a frame transmission when said slot count reaches a predetermined value; and calibrating said slot count upon completion of said frame transmission, said calibration being accomplished by using slot(i)=(seq(i)-seq(j)) mod where seq(i) and seq(j) denote a relative position of addresses of station i and station j in an address sequence that records the order of the round robin service, at least one frame of station j being captured in the air by station i, and where C1 denotes the slot count for a station to start a new round of backing off, the same value of C1 being shared by all stations in said contention based network, wherein there is a constant delay time for frame transmissions equal to DIFS plus one slot time. receiving a slot count based on a number of stations in said contention-based network; adjusting said slot count and adopting a round robin service; initiating a frame transmission when said slot count reaches a predetermined value; and calibrating said slot count upon completion of said frame transmission, said calibration being accomplished by using slot(i)=(seq(i)-seq(j)) mod where seq(i) and seq(j) denote a relative position of addresses of station i and station j in an address sequence that records the order of the round robin service, at least one frame of station j being captured in the air by station i, and where C1 denotes the slot count for a station to start a new round of backing off, the same value of C1 being shared by all stations in said contention based network, wherein there is a constant delay time for frame transmissions equal to DIFS plus one slot time.
Method of modeling and/or obtaining cardiac tissue or tissue-like structures comprising culturing a embryonic stem cell-derived first cell type in the presence of at least one embryonic second cell type; and allowing integration and alignment of said at least two cell types into cardiac tissue or tissue-like structures; wherein said at least one second cell type are fibroblasts or endothelial cells; provided that the cells are not derived from a human embryo.
A method for producing Cu67 radioisotope comprising irradiating a metallic Zn68 target ingot, contained within a sealed capsule and in intimate contact therewith, with a high energy gamma ray beam to convert at least a portion of the Zn68 to Cu67, and then isolating Cu67 from the irradiated target; wherein the capsule is composed of a ceramic material that does not react chemically with molten zinc; the ceramic material is selected to promote close physical contact between the ceramic and the solid Zn68 target ingot to provide a tight interface for good thermal conductivity; and the Zn68 is substantially free of traces of residual oxygen that interfere with contact of the Zn68 to the capsule.
A system for air traffic control and/or air traffic management for aircraft (1, 2), the system being designed for use of Automatic Dependent Surveillance-Broadcast (ADS-B) monitoring and comprising a plurality of receiving stations (20, 26), which are spaced apart from one another and are each designed to receive an ADS-B broadcast signal (5, 6) emitted by a transmitting station (3, 4) of an aircraft (1, 2) requiring air traffic control and/or air traffic management, and ground-based processing means for processing the received broadcast signal (5, 6), characterized in that the receiving stations (20, 26) are designed to receive a 1090 MHz Mode S extended squitter, 1090 MS ES, signal as the ADS-B broadcast signal (5, 6), and at least some of the receiving stations (20, 26) are disposed on a respective satellite, which are designed to receive the ADS-B broadcast signal (5, 6) and forward at least some of the data contained therein via a radio transmission link (21; 25, 27) to a satellite ground control station, and onward to an air traffic control and/or air traffic management center or other organizations, the satellite receiving stations (20, 26) comprising at least one transmitting unit, which is designed to transmit another broadcast signal including information about the positions of aircraft in the form of Traffic Information Services Broadcast (TIS-B).
Method for producing an extruded bearing journal, which extends in a longitudinal direction and which has a lateral surface surrounding a longitudinal central axis of the bearing journal and has a face surface delimiting the bearing journal in an axial direction at a free end, wherein the bearing journal is extruded in an extrusion tool by means of at least one extrusion punch (22, 23) and, after the extrusion of the bearing journal, reworking of the bearing journal is performed in order to improve the cylindricity of the bearing journal at least over a section of the longitudinal extent of the bearing journal, wherein, during the reworking, the bearing journal is arranged, at least over a section of its longitudinal extent adjoining its free end, in a cavity that is delimited in a radial direction of the bearing journal by a wall surface surrounding the lateral surface of the bearing journal, and a reworking punch which is movable in the longitudinal direction of the bearing journal is moved toward the free end of the bearing journal and is pressed against the face surface of the bearing journal and, in this way, a plastic deformation of the bearing journal, with a flow of material of the bearing journal, is effected, characterized in that, after the extrusion, the bearing journal is removed from the pressing tool and a sleeve is pushed onto the bearing journal in a longitudinal direction of the bearing journal, which sleeve has the wall surface that surrounds the lateral surface of the bearing journal at least over that section of the longitudinal extent of the bearing journal which adjoins the free end of the bearing journal, in that, after the plastic deformation of the bearing journal by means of the reworking punch, as the sleeve is pulled off the bearing journal in the longitudinal direction of the bearing journal, a flow of material of the bearing journal is effected by the sleeve, wherein the reworking punch is pressed against the face surface of the bearing journal at least until the sleeve has been partially pulled off the bearing journal.
Trim arrangement for the interior fittings of a motor vehicle, in particular for the interior fittings of a motor vehicle door, comprising an operating element that can be mechanically connected to a fastening structure, at least one trim element that is arranged at least in portions on an outer side of the operating element, and at least one force transmission element that is arranged on a side of the trim element facing away from the operating element and that forms at least a first contact element for contacting the fastening structure and at least a second contact element for contacting the trim element, so that when a force is applied to the trim arrangement by at least one component perpendicular to the side of the trim element facing away from the operating element and the operating element is displaced, caused by the application of the force, the relative position of the trim element to the operating element remains at least substantially unchanged.
Non-therapeutic use of a polyaniline polymer or copolymer as an antimicrobial material, wherein the aniline polymer is polyaminobenzoic acid Poly3ABA (poly 3-aminobenzoic acid homopolymer), or PolySO 3 H (poly 3-aminobenzenesulfonic acid homopolymer) and wherein the aniline copolymer is selected from the group consisting of: 3ABAPANI (1:1 copolymer of 3-aminobenzoic acid and aniline), OABAPANI (1:1 copolymer of anthranilic acid and aniline), 3EABPANI (1:1 copolymer of ethyl 3-aminobenzate and aniline), SO 3 HPANI (1:1 copolymer of aniline with functionalized aniline (-SO 3 H)) in ES form, ClPANI (1:1 copolymer of aniline with functionalized aniline (-Cl)) in ES form, OCH 3 PANI (1:1 copolymer of aniline with functionalized aniline (-OCH 3)) in ES form, and CH 3 PANI (1:1 copolymer of aniline with functionalized aniline (-CH 3)) in ES form. 3ABAPANI (1:1 copolymer of 3-aminobenzoic acid and aniline), OABAPANI (1:1 copolymer of anthranilic acid and aniline), 3EABPANI (1:1 copolymer of ethyl 3-aminobenzate and aniline), SO 3 HPANI (1:1 copolymer of aniline with functionalized aniline (-SO 3 H)) in ES form, ClPANI (1:1 copolymer of aniline with functionalized aniline (-Cl)) in ES form, OCH 3 PANI (1:1 copolymer of aniline with functionalized aniline (-OCH 3)) in ES form, and CH 3 PANI (1:1 copolymer of aniline with functionalized aniline (-CH 3)) in ES form.
A fuel spraying apparatus for a gas turbine engine having a combustor, comprising: a first fuel spraying section configured to spray fuel for diffusion combustion, first fuel spraying section including a spraying nozzle member; a second fuel spraying section configured to spray fuel for premixed combustion, the second fuel spraying section being disposed so as to surround the first fuel spraying section, the second fuel spraying section including a cylindrical intermediate wall; and an air curtain generating section disposed between the first fuel spraying section and the second fuel spraying section, the air curtain generating section being configured to generate an air curtain which defines an outer edge of a diffusion combustion area in a combustion chamber of the combustor, wherein the air curtain generating section includes a ring cover member for blocking downstream ends of the spraying nozzle member and the cylindrical intermediate wall, and wherein the ring cover member is provided with an air flow path communicating with the combustion chamber, characterised in that the air flow path is configured to supply air curtain forming air into the combustion chamber, and that the first and second fuel spraying sections comprise an inside block and an outside block, the inside block including a main unit of the first fuel spraying section and a main unit of the second fuel spraying section, the outside block including the spraying nozzle member, the ring cover member, the cylindrical intermediate wall and a cylindrical outer peripheral wall, the inside block and the outside block being separable from each other. a first fuel spraying section configured to spray fuel for diffusion combustion, first fuel spraying section including a spraying nozzle member; a second fuel spraying section configured to spray fuel for premixed combustion, the second fuel spraying section being disposed so as to surround the first fuel spraying section, the second fuel spraying section including a cylindrical intermediate wall; and an air curtain generating section disposed between the first fuel spraying section and the second fuel spraying section, the air curtain generating section being configured to generate an air curtain which defines an outer edge of a diffusion combustion area in a combustion chamber of the combustor, wherein the air curtain generating section includes a ring cover member for blocking downstream ends of the spraying nozzle member and the cylindrical intermediate wall, and wherein the ring cover member is provided with an air flow path communicating with the combustion chamber, characterised in that the air flow path is configured to supply air curtain forming air into the combustion chamber, and that the first and second fuel spraying sections comprise an inside block and an outside block, the inside block including a main unit of the first fuel spraying section and a main unit of the second fuel spraying section, the outside block including the spraying nozzle member, the ring cover member, the cylindrical intermediate wall and a cylindrical outer peripheral wall, the inside block and the outside block being separable from each other.