A tissue therapy device, the device comprising: a sealing layer with a resealable interface, said resealable interface comprising: a base member attached to said esealing layer and comprising an aperture, and a cap member configured to form a complementary interfit with, and removably seal, the aperture of the base member, the cap member being secured to the base member by complementary threads in the cap member and base member, by a snapfit or by a latch, wherein the base member and the cap member form a sealed enclosure around an area of tissue; and a suction apparatus comprising: a body with a variable volume portion bounded by a rigid wall portion and a reciprocating mechanism having a plunger configured to sealably slide along the rigid wall portion, the reciprocating mechanism being attached to a handle for drawing the reciprocating mechanism back to generate reduced pressure in the variable volume portion; wherein the reciprocating mechanism is held in a withdrawn position within the rigid wall portion to create and maintain a negative pressure within the sealed enclosure, the reciprocating mechanism being held by interlocking teeth on a shaft of the reciprocating mechanism and the body. a sealing layer with a resealable interface, said resealable interface comprising: a base member attached to said esealing layer and comprising an aperture, and a cap member configured to form a complementary interfit with, and removably seal, the aperture of the base member, the cap member being secured to the base member by complementary threads in the cap member and base member, by a snapfit or by a latch, wherein the base member and the cap member form a sealed enclosure around an area of tissue; and a base member attached to said esealing layer and comprising an aperture, and a cap member configured to form a complementary interfit with, and removably seal, the aperture of the base member, the cap member being secured to the base member by complementary threads in the cap member and base member, by a snapfit or by a latch, wherein the base member and the cap member form a sealed enclosure around an area of tissue; and a suction apparatus comprising: a body with a variable volume portion bounded by a rigid wall portion and a reciprocating mechanism having a plunger configured to sealably slide along the rigid wall portion, the reciprocating mechanism being attached to a handle for drawing the reciprocating mechanism back to generate reduced pressure in the variable volume portion; wherein the reciprocating mechanism is held in a withdrawn position within the rigid wall portion to create and maintain a negative pressure within the sealed enclosure, the reciprocating mechanism being held by interlocking teeth on a shaft of the reciprocating mechanism and the body. a body with a variable volume portion bounded by a rigid wall portion and a reciprocating mechanism having a plunger configured to sealably slide along the rigid wall portion, the reciprocating mechanism being attached to a handle for drawing the reciprocating mechanism back to generate reduced pressure in the variable volume portion; wherein the reciprocating mechanism is held in a withdrawn position within the rigid wall portion to create and maintain a negative pressure within the sealed enclosure, the reciprocating mechanism being held by interlocking teeth on a shaft of the reciprocating mechanism and the body.