mhurhangee/ep-ind-claims huggingface dataset:
A travoprost sustained release biodegradable intracameral implant comprising: - a biodegradable hydrogel, wherein the hydrogel comprises a polymer network comprising one or more units of polyalkylene glycol, and travoprost particles, - the travoprost particles being in the form of travoprost intermixed with a biodegradable polymer comprising a polylactide, and - the travoprost particles being dispersed within the hydrogel, wherein the polymer network is formed by reacting an electrophilic group-containing multi-arm-polymer precursor with a nucleophilic group-containing cross-linking agent, the electrophilic group is selected from the group consisting of a succinimidylglutarate group and a succinimidylazelate group, and the multi-arm polymer precursor is selected from the group consisting of 8-arm-15K-SG polyethylene glycol or 8-arm-15K-SAZ polyethylene glycol, the nucleophilic group-containing cross-linking agent is a trilysine, and the polyalkylene glycol units are crosslinked via a hydrolyzable linker having the formula wherein m is 2 or 6, wherein the implant has a length of about 1.00 mm to about 2.50 mm and a diameter of not more than 0.30 mm in its dried state, wherein the travoprost particles have an average diameter ranging from 1 to 75 μm determined by laser diffraction, and wherein the implant contains a dose of about 2 μg to about 30 μg of travoprost. - a biodegradable hydrogel, wherein the hydrogel comprises a polymer network comprising one or more units of polyalkylene glycol, and travoprost particles, - the travoprost particles being in the form of travoprost intermixed with a biodegradable polymer comprising a polylactide, and - the travoprost particles being dispersed within the hydrogel, wherein the polymer network is formed by reacting an electrophilic group-containing multi-arm-polymer precursor with a nucleophilic group-containing cross-linking agent, the electrophilic group is selected from the group consisting of a succinimidylglutarate group and a succinimidylazelate group, and the multi-arm polymer precursor is selected from the group consisting of 8-arm-15K-SG polyethylene glycol or 8-arm-15K-SAZ polyethylene glycol, the nucleophilic group-containing cross-linking agent is a trilysine, and the polyalkylene glycol units are crosslinked via a hydrolyzable linker having the formula wherein m is 2 or 6, wherein the implant has a length of about 1.00 mm to about 2.50 mm and a diameter of not more than 0.30 mm in its dried state, wherein the travoprost particles have an average diameter ranging from 1 to 75 μm determined by laser diffraction, and wherein the implant contains a dose of about 2 μg to about 30 μg of travoprost.
A method of communication comprising: receiving, at a first device of a data link group of a neighbor aware network, NAN, availability information from a second device of the data link group during a connection set-up phase of communication of the NAN or during a NAN discovery window, wherein the connection set-up phase includes an exchange of device capability information; wherein the availability information indicates that the second device is available during a service data transmission window of the data link group to receive service data from the first device; and based on the availability information sending service data from the first device to the second device during the service data transmission window without performing a message exchange to determine an availability of the second device, wherein the service data is associated with a service shared by the first device with the devices of the data link group. receiving, at a first device of a data link group of a neighbor aware network, NAN, availability information from a second device of the data link group during a connection set-up phase of communication of the NAN or during a NAN discovery window, wherein the connection set-up phase includes an exchange of device capability information; wherein the availability information indicates that the second device is available during a service data transmission window of the data link group to receive service data from the first device; and based on the availability information sending service data from the first device to the second device during the service data transmission window without performing a message exchange to determine an availability of the second device, wherein the service data is associated with a service shared by the first device with the devices of the data link group.
A multi-purpose phacoemulsification needle (10; 50; 60; 100; 200; 300; 400; 500), comprising: a needle body (12; 102; 202; 302; 402; 502) disposed about a centerline (30; 104; 204) and having a lumen (14; 108; 308; 408) 508) disposed therein, the lumen having a first cross-sectional area normal to the centerline; a proximal end adapted for attachment to a phacoemulsification handpiece; and a distal tip (20; 112; 212; 312; 412; 512) comprising an arcuate surface (24; 124; 214) and a face (26; 114; 216) with a port (38; 118; 218) therein, the port having a second cross-sectional area in a plane generally parallel to the face and being in fluid communication with an internal cavity and the needle body lumen, the internal cavity having a third cross-sectional area normal to the centerline and being in fluid communication with the lumen; the internal cavity comprising a surface portion disposed about the port (38; 118), the distal tip comprising a continuous surface free of discontinuities that includes the surface portion and a distal portion of the needle body; the third cross-sectional area being greater than the first cross-sectional area and greater than the second cross-sectional area, wherein the distal tip further comprises: a flat surface disposed at an acute angle relative to the centerline; the port being disposed within the flat surface; a continuous surface free of discontinuities comprising the flat surface, a distal portion of the lumen, and a distal portion of the needle body. a needle body (12; 102; 202; 302; 402; 502) disposed about a centerline (30; 104; 204) and having a lumen (14; 108; 308; 408) 508) disposed therein, the lumen having a first cross-sectional area normal to the centerline; a proximal end adapted for attachment to a phacoemulsification handpiece; and a distal tip (20; 112; 212; 312; 412; 512) comprising an arcuate surface (24; 124; 214) and a face (26; 114; 216) with a port (38; 118; 218) therein, the port having a second cross-sectional area in a plane generally parallel to the face and being in fluid communication with an internal cavity and the needle body lumen, the internal cavity having a third cross-sectional area normal to the centerline and being in fluid communication with the lumen; the internal cavity comprising a surface portion disposed about the port (38; 118), the distal tip comprising a continuous surface free of discontinuities that includes the surface portion and a distal portion of the needle body; the third cross-sectional area being greater than the first cross-sectional area and greater than the second cross-sectional area, wherein the distal tip further comprises: a flat surface disposed at an acute angle relative to the centerline; the port being disposed within the flat surface; a continuous surface free of discontinuities comprising the flat surface, a distal portion of the lumen, and a distal portion of the needle body. a flat surface disposed at an acute angle relative to the centerline; the port being disposed within the flat surface; a continuous surface free of discontinuities comprising the flat surface, a distal portion of the lumen, and a distal portion of the needle body.
Tooth cleaning composition for application using a toothbrush, preferably toothpaste, dentifrice, tooth cleaning gel or toothpowder, comprising the following components: (i) cleaning body (ii) aroma composition comprising or consisting of: a) menthol, b) an amount of menthan carbonic acid-N-(4-methoxyphenyl)-amide (WS-12) masking the bitterness of the menthol as well as c) one, two or more further aroma substances, wherein the, several or all of the further aroma substances have log-K ow value in the range from 1.5 to 5. (i) cleaning body (ii) aroma composition comprising or consisting of: a) menthol, b) an amount of menthan carbonic acid-N-(4-methoxyphenyl)-amide (WS-12) masking the bitterness of the menthol as well as c) one, two or more further aroma substances, wherein the, several or all of the further aroma substances have log-K ow value in the range from 1.5 to 5. a) menthol, b) an amount of menthan carbonic acid-N-(4-methoxyphenyl)-amide (WS-12) masking the bitterness of the menthol as well as c) one, two or more further aroma substances, wherein the, several or all of the further aroma substances have log-K ow value in the range from 1.5 to 5.
A display apparatus comprising: a manipulator which receives a manipulation of a user; an image input part which inputs a three-dimensional image; a 3D image creator which generates a left-eye image and a right-eye image corresponding to the input 3D image for full screen display by enlarging twice or interpolating separated left-eye image data and right-eye image data; an image output part which alternately outputs the left-eye image and right-eye image; and a controller which, upon an input, through the manipulator, of a generation command of a 3D graphic user interface to display over the 3D image, controls to output only one of the generated left-eye image and the generated right-eye image and to output the GUI, wherein: upon the input of the generation command, the 3D image creator generates only the one of the left-eye image and the right-eye image which is output by the controller. a manipulator which receives a manipulation of a user; an image input part which inputs a three-dimensional image; a 3D image creator which generates a left-eye image and a right-eye image corresponding to the input 3D image for full screen display by enlarging twice or interpolating separated left-eye image data and right-eye image data; an image output part which alternately outputs the left-eye image and right-eye image; and a controller which, upon an input, through the manipulator, of a generation command of a 3D graphic user interface to display over the 3D image, controls to output only one of the generated left-eye image and the generated right-eye image and to output the GUI, wherein: upon the input of the generation command, the 3D image creator generates only the one of the left-eye image and the right-eye image which is output by the controller. upon the input of the generation command, the 3D image creator generates only the one of the left-eye image and the right-eye image which is output by the controller.
A compound, which is 5-(3-chloro-4-fluorophenyl)-7-cyclopropyl-3-(2-(3-fluoro-3-methylazetidin-1-yl)-2-oxoethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one of the formula: or a pharmaceutically acceptable salt thereof, for use in the treatment of schizophrenia, wherein the compound is administered in combination with an effective amount of one or more atypical antipsychotics.
An elevator comprising an elevator car, the elevator car comprising an interior for receiving a load to be transported; a car frame via which the elevator car is suspended by a roping, the car frame comprising a horizontally oriented cross beam extending across the vertical projection of the interior; and a plurality of weight elements (4,5) forming a line of weight elements and being suspended by the cross beam, wherein one or more of the weight elements (4,5) are oscillation dampers for dampening vertical oscillation of the car, characterized in that the oscillation damper comprises a damper body, preferably engaged with the cross beam; and one or more weight blocks carried by the damper body and vertically movable relative to the damper body; and one or more deformable members (4c, 4d; 4c,4d') between the one or more weight blocks and the damper body for resisting vertical movement of the one or more weight blocks relative to the damper body. an interior for receiving a load to be transported; a car frame via which the elevator car is suspended by a roping, the car frame comprising a horizontally oriented cross beam extending across the vertical projection of the interior; and a plurality of weight elements (4,5) forming a line of weight elements and being suspended by the cross beam, wherein one or more of the weight elements (4,5) are oscillation dampers for dampening vertical oscillation of the car, characterized in that the oscillation damper comprises a damper body, preferably engaged with the cross beam; and one or more weight blocks carried by the damper body and vertically movable relative to the damper body; and one or more deformable members (4c, 4d; 4c,4d') between the one or more weight blocks and the damper body for resisting vertical movement of the one or more weight blocks relative to the damper body.
A rigid cardboard foldable display unit comprising: - a rear wall having two side edges (68, 70), and two side walls (108, 110) respectively hingedly mounted to said two side edges and each having a free edge opposite to said side edges, said two side walls (108, 110) being adapted to be carried facing each other; - at least one bearing element including on the one hand a posterior edge hingedly mounted to said rear wall and an opposite anterior edge (40, 42, 116) extending between the free edges of said two facing side walls, and on the other hand an intermediate part (113, 115) extending from said posterior edge to said anterior edge to be able to form a receiving shelf; characterised in that said anterior edge (40, 42, 116) is hinged to said free edges, whereas said intermediate part (113, 115) is hingedly mounted to said anterior edge; and in that said two side walls (108, 110) are adapted to be respectively folded in two one towards the other along a medium fold line (17, 19) parallel to the side edge (68, 70) of said rear wall, whereas said intermediate part (113, 115) folds in two along a transverse fold line substantially perpendicular to the median fold lines (17, 19) to carry said intermediate part (113, 115) and said two side walls (108, 110) respectively folded in two against said rear wall. - a rear wall having two side edges (68, 70), and two side walls (108, 110) respectively hingedly mounted to said two side edges and each having a free edge opposite to said side edges, said two side walls (108, 110) being adapted to be carried facing each other; - at least one bearing element including on the one hand a posterior edge hingedly mounted to said rear wall and an opposite anterior edge (40, 42, 116) extending between the free edges of said two facing side walls, and on the other hand an intermediate part (113, 115) extending from said posterior edge to said anterior edge to be able to form a receiving shelf; characterised in that said anterior edge (40, 42, 116) is hinged to said free edges, whereas said intermediate part (113, 115) is hingedly mounted to said anterior edge; and in that said two side walls (108, 110) are adapted to be respectively folded in two one towards the other along a medium fold line (17, 19) parallel to the side edge (68, 70) of said rear wall, whereas said intermediate part (113, 115) folds in two along a transverse fold line substantially perpendicular to the median fold lines (17, 19) to carry said intermediate part (113, 115) and said two side walls (108, 110) respectively folded in two against said rear wall.
An electrosurgical instrument configured to ablate duodenal mucosal tissue, the instrument comprising: a flexible coaxial cable for conveying microwave energy from a generator located externally to the patient to a treatment site located inside a patient's duodenum; and an applicator located at a distal end of the flexible coaxial cable, the applicator having an energy delivery structure connected to receive microwave energy from the coaxial cable and to deliver the received microwave energy into biological tissue at the treatment site, wherein the applicator includes a radially extendable balloon arranged to move the energy delivery structure into contact with duodenal mucosal tissue at the treatment region, and wherein the energy delivery structure comprises: an internal conductive element disposed within a volume enclosed by the balloon, the internal conductive element being electrically connected to an inner conductor of the flexible coaxial cable to launch the microwave energy into biological tissue at the treatment site; characterised in that the energy delivery structure further comprises an outer conductive structure formed on an outer surface of the balloon, the outer conductive structure being electrically connected to an outer conductor of the flexible coaxial cable. a flexible coaxial cable for conveying microwave energy from a generator located externally to the patient to a treatment site located inside a patient's duodenum; and an applicator located at a distal end of the flexible coaxial cable, the applicator having an energy delivery structure connected to receive microwave energy from the coaxial cable and to deliver the received microwave energy into biological tissue at the treatment site, wherein the applicator includes a radially extendable balloon arranged to move the energy delivery structure into contact with duodenal mucosal tissue at the treatment region, and wherein the energy delivery structure comprises: an internal conductive element disposed within a volume enclosed by the balloon, the internal conductive element being electrically connected to an inner conductor of the flexible coaxial cable to launch the microwave energy into biological tissue at the treatment site; characterised in that the energy delivery structure further comprises an outer conductive structure formed on an outer surface of the balloon, the outer conductive structure being electrically connected to an outer conductor of the flexible coaxial cable. an internal conductive element disposed within a volume enclosed by the balloon, the internal conductive element being electrically connected to an inner conductor of the flexible coaxial cable to launch the microwave energy into biological tissue at the treatment site; characterised in that the energy delivery structure further comprises an outer conductive structure formed on an outer surface of the balloon, the outer conductive structure being electrically connected to an outer conductor of the flexible coaxial cable.
Metering device for metering a sealant for sealing a sewer wall, the metering device comprising a housing which is provided with a sealant supply and a sealant discharge, wherein the sealant supply is configured for supplying sealant to a supply space provided in the housing and the sealant discharge is configured for discharging sealant from the supply space and supplying it to the sewer wall, wherein an inhibiting device is provided for inhibiting the supply of sealant from the supply space to the sealant supply, wherein the metering device comprises a flushing agent supply which is configured for supplying flushing agent to the supply space and the sealant discharge for removing sealant which is present in the supply space and the sealant discharge, wherein the sealant supply comprises a first sealant supply and a second sealant supply which are configured for separately supplying a first sealant component via the first sealant supply and a second sealant component via the second sealant supply to the supply space, wherein the supply space comprises a first supply space and a second supply space which is separate from the first supply space, wherein the first sealant supply is configured for supplying the first sealant component to the first supply space and the second sealant supply is configured for supplying the second sealant component to the second supply space. wherein the sealant supply comprises a first sealant supply and a second sealant supply which are configured for separately supplying a first sealant component via the first sealant supply and a second sealant component via the second sealant supply to the supply space, wherein the supply space comprises a first supply space and a second supply space which is separate from the first supply space, wherein the first sealant supply is configured for supplying the first sealant component to the first supply space and the second sealant supply is configured for supplying the second sealant component to the second supply space.
An angle nut runner comprising: a body having a side; an output shaft rotatably supported approximately perpendicular to a rotating shaft of a drive source; a strain measuring mechanism for measuring a strain generated in the output shaft, the strain measuring mechanism comprising: an internal gear having an outer cylinder, the internal gear engaging the output shaft and the outer cylinder being fixed on the side of the body; and the strain measuring mechanism further comprising a strain gauge characterised in that the strain gauge is pasted on the outer cylinder of the internal gear. a body having a side; an output shaft rotatably supported approximately perpendicular to a rotating shaft of a drive source; a strain measuring mechanism for measuring a strain generated in the output shaft, the strain measuring mechanism comprising: an internal gear having an outer cylinder, the internal gear engaging the output shaft and the outer cylinder being fixed on the side of the body; and the strain measuring mechanism further comprising a strain gauge characterised in that the strain gauge is pasted on the outer cylinder of the internal gear. an internal gear having an outer cylinder, the internal gear engaging the output shaft and the outer cylinder being fixed on the side of the body; and the strain measuring mechanism further comprising a strain gauge characterised in that the strain gauge is pasted on the outer cylinder of the internal gear.