mhurhangee/ep-ind-claims huggingface dataset:
An injection device for dispensing in use a substance from a dual or multi-chamber cartridge, said cartridge having a bung moveable in a first, reconstitution phase of movement and a second, dosing phase of movement, said device comprising: a body portion; a plunger mounted in said body portion for longitudinal movement with respect thereto in a forward dispensing direction to co-operate in use with said bung; a plunger drive element disposed adjacent said plunger for driving said plunger; said plunger having a drive portion (24") adapted to mate with a complementary drive portion on said plunger drive element for imparting dosing movement to said plunger; characterised in that said drive portion (24") extends only partly along said plunger to leave a forward non-drive portion and the device is configured to allow said plunger to be moved longitudinally forward during a reconstitution phase from a position with the non-drive portion adjacent said plunger drive element, to bring the drive portion (24") of the plunger into driving engagement with the drive portion on said plunger drive element. a body portion; a plunger mounted in said body portion for longitudinal movement with respect thereto in a forward dispensing direction to co-operate in use with said bung; a plunger drive element disposed adjacent said plunger for driving said plunger; said plunger having a drive portion (24") adapted to mate with a complementary drive portion on said plunger drive element for imparting dosing movement to said plunger; characterised in that said drive portion (24") extends only partly along said plunger to leave a forward non-drive portion and the device is configured to allow said plunger to be moved longitudinally forward during a reconstitution phase from a position with the non-drive portion adjacent said plunger drive element, to bring the drive portion (24") of the plunger into driving engagement with the drive portion on said plunger drive element.
A fusion polypeptide comprising in an N-terminal to C-terminal direction: an immunoglobulin domain, wherein the immunoglobulin domain comprises an Fc domain; a trimerization domain; and a receptor binding domain; wherein the receptor binding domain is: a) an OX-40L receptor binding domain, which is capable of binding to the OX-40 receptor and stimulating at least one OX-40 mediated activity; and optionally comprises a polypeptide sequence at least 95% identical to SEQ ID NO:2, or optionally comprises an extracellular domain of OX-40 ligand (OX-40L); or b) an anti-OX40 receptor antibody, or antigen-binding fragment thereof, which is capable of stimulating at least one OX-40 mediated activity, wherein the OX-40 mediated activity is optionally CD4+ T cell proliferation; and wherein the fusion polypeptide self-assembles into a trimeric or a hexameric fusion protein. an immunoglobulin domain, wherein the immunoglobulin domain comprises an Fc domain; a trimerization domain; and a receptor binding domain; wherein the receptor binding domain is: a) an OX-40L receptor binding domain, which is capable of binding to the OX-40 receptor and stimulating at least one OX-40 mediated activity; and optionally comprises a polypeptide sequence at least 95% identical to SEQ ID NO:2, or optionally comprises an extracellular domain of OX-40 ligand (OX-40L); or b) an anti-OX40 receptor antibody, or antigen-binding fragment thereof, which is capable of stimulating at least one OX-40 mediated activity, wherein the OX-40 mediated activity is optionally CD4+ T cell proliferation; and a) an OX-40L receptor binding domain, which is capable of binding to the OX-40 receptor and stimulating at least one OX-40 mediated activity; and optionally comprises a polypeptide sequence at least 95% identical to SEQ ID NO:2, or optionally comprises an extracellular domain of OX-40 ligand (OX-40L); or b) an anti-OX40 receptor antibody, or antigen-binding fragment thereof, which is capable of stimulating at least one OX-40 mediated activity, wherein the OX-40 mediated activity is optionally CD4+ T cell proliferation; and
A fuel battery comprising: a fuel cell including a solid oxide electrolyte layer having a first main surface and a second main surface, a first electrode disposed on the first main surface and serving as one of a cathode and an anode, and a second electrode disposed on the second main surface and serving as the other one of the cathode and the anode, the fuel cell generating electric power through a power generating reaction of reactant gases; an interconnector (41, 45) disposed so as to face the first electrode; and a current collecting member that electrically connects the first electrode to the interconnector (41, 45); the fuel battery being characterized in that the first electrode includes an inner portion connected to the current collecting member and an outer portion disposed outward of the current collecting member and having a thickness larger than the thickness of the inner portion, wherein the outer portion is disposed at least on a reactant gas inflow side of the first electrode to which one of the reactant gases is supplied, wherein the height of the outer portion with respect to the inner portion is 10 μm or more and 200 μm or less. a fuel cell including a solid oxide electrolyte layer having a first main surface and a second main surface, a first electrode disposed on the first main surface and serving as one of a cathode and an anode, and a second electrode disposed on the second main surface and serving as the other one of the cathode and the anode, the fuel cell generating electric power through a power generating reaction of reactant gases; an interconnector (41, 45) disposed so as to face the first electrode; and a current collecting member that electrically connects the first electrode to the interconnector (41, 45); the fuel battery being the first electrode includes an inner portion connected to the current collecting member and an outer portion disposed outward of the current collecting member and having a thickness larger than the thickness of the inner portion, the outer portion is disposed at least on a reactant gas inflow side of the first electrode to which one of the reactant gases is supplied,
A method of managing a hierarchical Translation Lookaside Buffer, TLB, comprising: replicating an entry from a Level-1 TLB, L1 TLB, to a Level-0 TLB, L0 TLB, when a virtual address misses in the L0 TLB and hits in the L1 TLB, characterized by: subsequently locking the entry in the L0 TLB against replacement in response to an indicator in the L1 TLB entry. replicating an entry from a Level-1 TLB, L1 TLB, to a Level-0 TLB, L0 TLB, when a virtual address misses in the L0 TLB and hits in the L1 TLB, characterized by: subsequently locking the entry in the L0 TLB against replacement in response to an indicator in the L1 TLB entry. subsequently locking the entry in the L0 TLB against replacement in response to an indicator in the L1 TLB entry.
A network device for efficiently determining acceptable link-based loop free alternates, LFAs, in a computer network to protect a protected element, the network device comprising: one or more network interfaces; a processor coupled to the one or more network interfaces and configured to execute an LFA processes; and a memory adapted to store the LFA process executable by the processor, the LFA process configured to: i) distinguish one or more other network devices of the network as network edge devices or network core devices, ii) determine whether a branch of a shortest path tree rooted at a neighboring network device, that includes the protected element, leads toward a network edge device, and iii) if the branch of the SPT rooted at a neighboring network device, that includes the protected element, does not lead toward a network edge device, determine that the neighboring network device is an acceptable LFA. one or more network interfaces; a processor coupled to the one or more network interfaces and configured to execute an LFA processes; and a memory adapted to store the LFA process executable by the processor, the LFA process configured to: i) distinguish one or more other network devices of the network as network edge devices or network core devices, ii) determine whether a branch of a shortest path tree rooted at a neighboring network device, that includes the protected element, leads toward a network edge device, and iii) if the branch of the SPT rooted at a neighboring network device, that includes the protected element, does not lead toward a network edge device, determine that the neighboring network device is an acceptable LFA. i) distinguish one or more other network devices of the network as network edge devices or network core devices, ii) determine whether a branch of a shortest path tree rooted at a neighboring network device, that includes the protected element, leads toward a network edge device, and iii) if the branch of the SPT rooted at a neighboring network device, that includes the protected element, does not lead toward a network edge device, determine that the neighboring network device is an acceptable LFA.
A base plate for an ostomy appliance including selective sensor points, the base plate comprising: a first adhesive layer comprising: a stomal opening with a center point, a proximal surface configured to be attached to a skin surface of a user, and a plurality of sensor point openings (260A, 260B, 262A, 262B, 264A, 264B) arranged circumferentially around the center point at respective radial distances; and a plurality of electrodes located distally of the first adhesive layer, the plurality of electrodes comprising a first leakage electrode and a second leakage electrode, a sensing part of the first leakage electrode aligning with a first sensor point opening of the plurality of sensor point openings (260A, 260B, 262A, 262B, 264A, 264B) of the first adhesive layer and a sensing part of the second leakage electrode aligning with a second sensor point opening of the plurality of sensor point openings (260A, 260B, 262A, 262B, 264A, 264B) of the first adhesive layer to form a leak sensor. a first adhesive layer comprising: a stomal opening with a center point, a proximal surface configured to be attached to a skin surface of a user, and a plurality of sensor point openings (260A, 260B, 262A, 262B, 264A, 264B) arranged circumferentially around the center point at respective radial distances; and a plurality of electrodes located distally of the first adhesive layer, the plurality of electrodes comprising a first leakage electrode and a second leakage electrode, a sensing part of the first leakage electrode aligning with a first sensor point opening of the plurality of sensor point openings (260A, 260B, 262A, 262B, 264A, 264B) of the first adhesive layer and a sensing part of the second leakage electrode aligning with a second sensor point opening of the plurality of sensor point openings (260A, 260B, 262A, 262B, 264A, 264B) of the first adhesive layer to form a leak sensor.
A formulation comprising cyclosporin A form 2 and a vehicle selected from carboxymethyl cellulose, hydroxypropyl methyl cellulose, hydroxyethyl cellulose, hyaluronic acid, polyvinylpyrrolidone, cross-linked polyacrylic acid polymer, and poloxamer, with the proviso that when the vehicle is selected from carboxymethyl cellulose, hydroxypropyl methyl cellulose, hydroxyethyl cellulose, hyaluronic acid, polyvinylpyrrolidone, or poloxamer, the cyclosporin A form 2 is at a concentration of about 0.01 % (w/v) to about 10% (w/v).
A method (100, 110) for producing a tube of a nickel-based alloy, the method comprising: (a) hot working a nicked-based alloy casting into a pretubular-shaped workpiece or into a cylindrical bar; (b) trepanning the cylindrical bar or machining an inner diameter of the pretubular-shaped workpiece to obtain a tubular workpiece (201, 301); and a single step of (c) cold working the tubular workpiece (201, 301). (a) hot working a nicked-based alloy casting into a pretubular-shaped workpiece or into a cylindrical bar; (b) trepanning the cylindrical bar or machining an inner diameter of the pretubular-shaped workpiece to obtain a tubular workpiece (201, 301); and
Cutter for a vegetation cutting tool comprising a mounting portion for mounting the cutter to a rotary support head of the vegetation cutting tool, wherein the mounting portion has at least one longitudinal axis, and at least one blade portion for cutting vegetation, wherein the blade portion radially extends away from the longitudinal axis and has a first side and a second side opposite from the first side, wherein the longitudinal axis is at least substantially at a right angle to the first side and second side, wherein the mounting portion further comprises a first mounting section and a second mounting section for radially supporting the cutter when mounted to the rotary support head, wherein the first mounting section has a first outer circumference which axially extends away from first side of the blade portion and has at least a first outer diameter and wherein the second mounting section has a second outer circumference which axially extends away from the second side of the blade portion and has at least a second outer diameter, characterised in that the first diameter is bigger than the second diameter.
A method of producing a three-dimensional tissue having a vascular system structure, wherein the method comprises: (a) a step of producing a template of a vascular system structure using a gel; (b) a step of forming a three-dimensional tissue in a vicinity of the template; (c) a step of dissolving the template using a cationic solution; and (d) a step of seeding at least one of a blood vessel endothelial cell or a lymphatic vessel endothelial cell in a void remaining after the dissolution of the template. (a) a step of producing a template of a vascular system structure using a gel; (b) a step of forming a three-dimensional tissue in a vicinity of the template; (c) a step of dissolving the template using a cationic solution; and (d) a step of seeding at least one of a blood vessel endothelial cell or a lymphatic vessel endothelial cell in a void remaining after the dissolution of the template.
Rail vehicle having a bogie which is covered in such a manner that there is present a bogie cavity which is formed by a covering arrangement and walls (8, 4) adjacent to the bogie in the underfloor region of the rail vehicle, and having a device for producing pressurized air, characterized in that the device for producing pressurized air is connected in technical flow terms to an air inlet device in the walls (8, 9) of the bogie cavity in such a manner that the air can be blown into the bogie cavity.
A method for automatically detecting portions of a software application to be secured, the method comprising the following steps: (a) providing program code of the software application; (b) identifying calls of API functions for establishing network connections in the program code and detecting a connection variable for an identified call that represents the network connection; (c) identifying transaction variables and preferably transaction constants used in connection with a detected connection variable, and storing information about identified transaction variables and preferably transaction constants in a data structure, which relates to portions of the software application to be secured; and (d) identifying assignment variables and/or assignment constants associated with an assignment of a value to one of the identified transaction variables and storing information about the identified assignment variables and/or assignment constants in the data structure. (a) providing program code of the software application; (b) identifying calls of API functions for establishing network connections in the program code and detecting a connection variable for an identified call that represents the network connection; (c) identifying transaction variables and preferably transaction constants used in connection with a detected connection variable, and storing information about identified transaction variables and preferably transaction constants in a data structure, which relates to portions of the software application to be secured; and (d) identifying assignment variables and/or assignment constants associated with an assignment of a value to one of the identified transaction variables and storing information about the identified assignment variables and/or assignment constants in the data structure.
A disc valve, in particular a multiway control valve, having a housing that has at least one inlet connection and at least one outlet connection (8, 9) as connections (7, 8, 9) for a liquid and/or gaseous medium, at least one rotatably mounted valve disc, in particular a ceramic valve disc, which is provided with at least one first through-flow opening and is arranged rotatably mounted in the housing, in order to fluidically connect and disconnect the connections (7, 8, 9) depending on its rotational position, wherein the valve disc rests flatly on at least one sealing disc, which is arranged in a torque-proof manner and has at least two second through-flow openings (19, 20), and a sealing element, which is arranged between the sealing disc and an intermediate floor of the housing and is elastically deformable, wherein the sealing element is configured in disc shape and has third through-flow openings (61, 62) that are aligned with the second through-flow openings (19, 20), characterized in that the intermediate floor has at least one retaining projection (63, 64) that engages in one of the third through-flow openings (61, 62) for positively locking anti-twist protection of the sealing element, and that further at least one axial projection is provided that is arranged off-center in a region, which is free of through-flow openings, on the intermediate floor, and that engages through a breakthrough of the sealing element at least fundamentally in a positively locking manner and is inserted at least in some areas into a receiving recess of the sealing disc for its anti-twist protection.
Method for operating a charging device of an energy store for a motor vehicle, wherein one rectifier device (7, 8, 9) for each phase is used for generating a charging voltage for the energy store during multiphase charging by the charging device, and only one rectifier device (7, 8, 9) is active during single-phase charging by the charging device, characterised in that, for each rectifier device (7, 8, 9), a usage quantity describing its previous use is determined, wherein the rectifier device (7, 8, 9) hitherto used least is used for the charging process in the case of a single-phase charging process.
An expansion anchor made of steel with an anchor bolt which extends along a longitudinal axis from a rear end to a front end on the insertion side, wherein the anchor bolt has a shaft with a load application means, on which an expansion body of the anchor bolt is arranged in front of the load application means such that it cannot move relative to the shaft, wherein the expansion body has an expansion portion which widens conically toward the insertion-side front end of the anchor bolt at a first cone angle (Ws) up to a maximum diameter, wherein the expansion anchor has an expansion sleeve which is arranged on the anchor bolt and is expandable by a displacement of the anchor bolt relative to the expansion sleeve and a resulting retraction of the expansion portion into the expansion sleeve, wherein no sliding coating is arranged between the spreader body and the spreader sleeve, and wherein the expansion sleeve has a plurality of expansion segments, each of which comprises a base body having a first wall thickness (t G), on which an extension having a second wall thickness (t F) reduced by a thickness difference (dt) relative to the first wall thickness (t G) is arranged on the insertion side, wherein the transition from the base body to the extension is formed by a diameter step on the outside of the expansion sleeve, which has a height corresponding to the thickness difference (dt), and wherein the extension on its inner side facing the anchor bolt is inclined at least on the insertion side at a second cone angle (W F) to the longitudinal axis, characterized in that the distance (dL) between the base body and the insertion-side front end of the extension applies: dL ≤ dt / tan W S + W F wherein the expansion anchor has an expansion sleeve which is arranged on the anchor bolt and is expandable by a displacement of the anchor bolt relative to the expansion sleeve and a resulting retraction of the expansion portion into the expansion sleeve, wherein no sliding coating is arranged between the spreader body and the spreader sleeve, and wherein the expansion sleeve has a plurality of expansion segments, each of which comprises a base body having a first wall thickness (t G), on which an extension having a second wall thickness (t F) reduced by a thickness difference (dt) relative to the first wall thickness (t G) is arranged on the insertion side, wherein the transition from the base body to the extension is formed by a diameter step on the outside of the expansion sleeve, which has a height corresponding to the thickness difference (dt), and wherein the extension on its inner side facing the anchor bolt is inclined at least on the insertion side at a second cone angle (W F) to the longitudinal axis, characterized in that the distance (dL) between the base body and the insertion-side front end of the extension applies: dL ≤ dt / tan W S + W F
A semiconductor device comprising: a first insulating film formed over a substrate; a first interconnection buried in at least a surface side of the first insulating film; a second insulating film formed on the first insulating film with the first interconnection buried in, and including a groove-shaped via-hole having a pattern which is bent at a right angle formed in a region above the first interconnection; and a first buried conductor filled in the groove-shaped via-hole, characterised in that a width at a bent portion of the pattern of the groove-shaped via-hole is not more than a width at a straight portion thereof. a first insulating film formed over a substrate; a first interconnection buried in at least a surface side of the first insulating film; a second insulating film formed on the first insulating film with the first interconnection buried in, and including a groove-shaped via-hole having a pattern which is bent at a right angle formed in a region above the first interconnection; and a first buried conductor filled in the groove-shaped via-hole, characterised in that a width at a bent portion of the pattern of the groove-shaped via-hole is not more than a width at a straight portion thereof.