A method for handling uplink-to-downlink interference between a first user equipment served by a first base station and a second user equipment served by a second base station, the first base station and the second base station being with full-duplex mode, wherein a base station with full-duplex mode is configured to simultaneously transmit and receive in the same frequency at the same time, the method comprising: receiving from the first user equipment information about a first received signal quality associated with the first base station and a second received signal quality associated with the second base station, and generating a full-duplex interference list associated with the second base station by putting the first user equipment into the full-duplex interference list if a difference between the first received signal quality and the second received signal quality is smaller than a threshold, wherein, for a serving base station, a full-duplex interference list is a list of user equipment which would generate non-negligible uplink-to-downlink interference to its neighbor base station, wherein the method further comprises: determining whether the first user equipment is in a full-duplex interference list associated with a second base station with full-duplex mode, if it is determined the first user equipment is in the full-duplex interference list, scheduling the downlink reception of the first user equipment on a first resource that is different from a second resource for scheduling uplink transmission of any second user equipment served by the second base station, wherein said any second user equipment is in a full-duplex interference list associated with the first base station. receiving from the first user equipment information about a first received signal quality associated with the first base station and a second received signal quality associated with the second base station, and generating a full-duplex interference list associated with the second base station by putting the first user equipment into the full-duplex interference list if a difference between the first received signal quality and the second received signal quality is smaller than a threshold, wherein, for a serving base station, a full-duplex interference list is a list of user equipment which would generate non-negligible uplink-to-downlink interference to its neighbor base station, wherein the method further comprises: determining whether the first user equipment is in a full-duplex interference list associated with a second base station with full-duplex mode, if it is determined the first user equipment is in the full-duplex interference list, scheduling the downlink reception of the first user equipment on a first resource that is different from a second resource for scheduling uplink transmission of any second user equipment served by the second base station, wherein said any second user equipment is in a full-duplex interference list associated with the first base station. determining whether the first user equipment is in a full-duplex interference list associated with a second base station with full-duplex mode, if it is determined the first user equipment is in the full-duplex interference list, scheduling the downlink reception of the first user equipment on a first resource that is different from a second resource for scheduling uplink transmission of any second user equipment served by the second base station, wherein said any second user equipment is in a full-duplex interference list associated with the first base station.