mhurhangee/ep-ind-claims huggingface dataset:
A microreactor having: a transfer means for transferring a liquid raw material using the pressure of a gas, a raw material tank for storing the liquid raw material, a gas feeding means for feeding a gas into the raw material tank, and a mixer for mixing the liquid raw material and another raw material with each other, wherein the transfer means is configured to transfer the liquid raw material stored in the raw material tank using the pressure of a gas in the raw material tank, wherein a pipe which connects the raw material tank and the mixer is provided with a small diameter portion, and wherein the small diameter portion comprises a tube having an inner diameter smaller than the inner diameter of a pipe positioned upstream and/or downstream of the tube, wherein the inner diameter of the small diameter portion is φ 0.01 to 0.3 mm, wherein the gas is nitrogen, and wherein a plurality of pipes are branched from the raw material tank, and the small diameter portion is connected to each of the branched pipes. a transfer means for transferring a liquid raw material using the pressure of a gas, a raw material tank for storing the liquid raw material, a gas feeding means for feeding a gas into the raw material tank, and a mixer for mixing the liquid raw material and another raw material with each other, wherein the transfer means is configured to transfer the liquid raw material stored in the raw material tank using the pressure of a gas in the raw material tank, wherein a pipe which connects the raw material tank and the mixer is provided with a small diameter portion, and wherein the small diameter portion comprises a tube having an inner diameter smaller than the inner diameter of a pipe positioned upstream and/or downstream of the tube, wherein the inner diameter of the small diameter portion is φ 0.01 to 0.3 mm, wherein the gas is nitrogen, and wherein a plurality of pipes are branched from the raw material tank, and the small diameter portion is connected to each of the branched pipes.
A hand tool, in particular a soldering gun, having at least one handle and a tool element protruding therefrom with an actuating end section on the free end, wherein the hand tool has more than one light (7, 8, 9) for illuminating a place of use of the hand tool, characterized in that the lights (7, 8, 9) are arranged on an end flange surrounding the tool element, in a handle end face of the handle extending radially relative to the tool element and oriented in the direction of the place of use, in a triangular arrangement and with an orientation for the shadow-free illumination of the place of use, wherein the handle is configured to be conically tapering from the end flange in the direction of an electrical connection cable and the lights (7, 8, 9) are arranged partly countersunk in a surface of the flat handle end face.
An apparatus (200, 400) comprising: a lens; a capacitive sensor array (106, 204, 206, 404, 406) positioned on a surface of the lens or within the lens, the capacitive sensor array arranged in a plurality of nodes, wherein each node of the plurality of nodes is positioned in a separate location and is electrically disconnected from each additional node on the surface of the lens or within the lens, and wherein the capacitive sensor array is configured to detect eye movement based at least on a proximity of the plurality of nodes to a part of an eye of a user; a frame (202, 402) configured to be worn on a head of the user and configured to support the lens and the capacitive sensor array positioned in front of the eye; at least one control circuit configured to receive signals from the capacitive sensor array, the control circuit positioned on or within the frame; a body electrode positioned on the frame and electrically connected to the control circuit, the body electrode configured to establish an electrical connection with a body of the user; and a conductive line connecting the body electrode to the control circuit. a lens; a capacitive sensor array (106, 204, 206, 404, 406) positioned on a surface of the lens or within the lens, the capacitive sensor array arranged in a plurality of nodes, wherein each node of the plurality of nodes is positioned in a separate location and is electrically disconnected from each additional node on the surface of the lens or within the lens, and wherein the capacitive sensor array is configured to detect eye movement based at least on a proximity of the plurality of nodes to a part of an eye of a user; a frame (202, 402) configured to be worn on a head of the user and configured to support the lens and the capacitive sensor array positioned in front of the eye; at least one control circuit configured to receive signals from the capacitive sensor array, the control circuit positioned on or within the frame; a body electrode positioned on the frame and electrically connected to the control circuit, the body electrode configured to establish an electrical connection with a body of the user; and a conductive line connecting the body electrode to the control circuit.
A preformed, three-dimensional, anatomically contoured prosthetic device (10,40,60,80,100,300,400) for reinforcing breast tissue and supporting a breast implant, which comprises: a back wall (11,41), the back wall having an upper rim (14,44) and a bottom portion situated opposite the upper rim; and a front wall (12,42), the front wall having an upper edge (7,47) and a bottom portion situated opposite the upper edge, the bottom portion of the front wall being joined to the bottom portion of the back wall to define a smoothly curved bottom periphery (13,43) to the prosthetic device, the front wall (12,42) being spaced apart from the back wall (11,41) to define therewith a receiving space adapted for at least partially receiving and supporting a breast implant therein, characterized in that said prosthetic device is seamless. a back wall (11,41), the back wall having an upper rim (14,44) and a bottom portion situated opposite the upper rim; and a front wall (12,42), the front wall having an upper edge (7,47) and a bottom portion situated opposite the upper edge, the bottom portion of the front wall being joined to the bottom portion of the back wall to define a smoothly curved bottom periphery (13,43) to the prosthetic device, the front wall (12,42) being spaced apart from the back wall (11,41) to define therewith a receiving space adapted for at least partially receiving and supporting a breast implant therein, characterized in that said prosthetic device is seamless.
A method for predicting one or more properties of bitumen using dielectric spectroscopy, wherein the method comprises: (a) dissolving a bitumen sample in a solvent to form a bitumen solution; (b) measuring the impedance response of the bitumen solution across a frequency range; (c) converting the impedance response of the bitumen solution to a dielectric loss factor; and (d) comparing the dielectric loss factor of the bitumen solution to a reference database comprising dielectric loss factors of reference bitumen samples to predict one or more properties of the bitumen sample comprising the bitumen solution; characterised in that measuring in step (b) is across a frequency range of from 1,400 Hz to 1,550 Hz and additionally across a frequency range of from 2,000 Hz to 3,000 Hz and/or across a frequency range of from 51,000 Hz to 54,000 Hz. (a) dissolving a bitumen sample in a solvent to form a bitumen solution; (b) measuring the impedance response of the bitumen solution across a frequency range; (c) converting the impedance response of the bitumen solution to a dielectric loss factor; and (d) comparing the dielectric loss factor of the bitumen solution to a reference database comprising dielectric loss factors of reference bitumen samples to predict one or more properties of the bitumen sample comprising the bitumen solution;
Method for covering a layer of a first material (108, 208) supported by a silicon substrate (100, 200) using a thus named grown semiconductor (110, 210) different from silicon, said first material being different from the material of the substrate and different from the grown semiconductor, said method comprising: - using at least one operation of spatially selective etching, producing on said substrate a surface layer called composite, comprising • at least said first material (106, 206) in a first region and • at least a second material (104, 204), different from the first material and different from the material of the substrate, in a second region, • said first and second regions being contiguous in at least an interface area (1070, 2070) having a difference in level between the surface (1060, 2060) of the material of said substrate (100, 200) in said first region and the surface (1000, 2000) of the material of said substrate in said second region; - at least one operation of chemical etching (128, 225) of said first material (108, 208) until at least a portion (107, 207) of the substrate is exposed around said interface; - growth (129, 130) of said grown semiconductor (109, 110) from the portion thus exposed, called the germination area. - using at least one operation of spatially selective etching, producing on said substrate a surface layer called composite, comprising • at least said first material (106, 206) in a first region and • at least a second material (104, 204), different from the first material and different from the material of the substrate, in a second region, • said first and second regions being contiguous in at least an interface area (1070, 2070) having a difference in level between the surface (1060, 2060) of the material of said substrate (100, 200) in said first region and the surface (1000, 2000) of the material of said substrate in said second region; • at least said first material (106, 206) in a first region and • at least a second material (104, 204), different from the first material and different from the material of the substrate, in a second region, • said first and second regions being contiguous in at least an interface area (1070, 2070) having a difference in level between the surface (1060, 2060) of the material of said substrate (100, 200) in said first region and the surface (1000, 2000) of the material of said substrate in said second region; - at least one operation of chemical etching (128, 225) of said first material (108, 208) until at least a portion (107, 207) of the substrate is exposed around said interface; - growth (129, 130) of said grown semiconductor (109, 110) from the portion thus exposed, called the germination area.
A method for increasing the aggregation-resistance of a protein comprising an antibody light chain variable domain (V L), the method comprising: a) modifying the V L by substituting an amino acid at one or more positions selected from the group consisting of residues 49, 50, 51, 52, 53 and 56 according to the numbering system of Kabat with a negatively charged amino acid; or b) modifying the V L such that it comprises negatively charged amino acids at two or more positions between residues 49 and 56 according to the numbering system of Kabat, wherein the unmodified protein does not comprise the two or more negatively charged amino acids; or c) when the protein further comprises an antibody heavy chain variable domain (V H), modifying the protein such that it comprises: (i) a negatively charged amino acid at one or more positions between residues 49 and 56 of the V L according to the numbering system of Kabat; and (ii) a negatively charged amino acid at one or more positions selected from the group consisting of residues 28, 30, 31, 32, 33 and 35 of the V H according to the numbering system of Kabat, wherein the protein prior to modification does not comprise a negatively charged amino acid at the positions in the V L and the V H; and wherein the method further comprises exposing the modified protein to heat and/or concentrating the protein and selecting a protein having a reduced propensity to aggregate compared to the unmodified protein. a) modifying the V L by substituting an amino acid at one or more positions selected from the group consisting of residues 49, 50, 51, 52, 53 and 56 according to the numbering system of Kabat with a negatively charged amino acid; or b) modifying the V L such that it comprises negatively charged amino acids at two or more positions between residues 49 and 56 according to the numbering system of Kabat, wherein the unmodified protein does not comprise the two or more negatively charged amino acids; or c) when the protein further comprises an antibody heavy chain variable domain (V H), modifying the protein such that it comprises: (i) a negatively charged amino acid at one or more positions between residues 49 and 56 of the V L according to the numbering system of Kabat; and (ii) a negatively charged amino acid at one or more positions selected from the group consisting of residues 28, 30, 31, 32, 33 and 35 of the V H according to the numbering system of Kabat, wherein the protein prior to modification does not comprise a negatively charged amino acid at the positions in the V L and the V H; (i) a negatively charged amino acid at one or more positions between residues 49 and 56 of the V L according to the numbering system of Kabat; and (ii) a negatively charged amino acid at one or more positions selected from the group consisting of residues 28, 30, 31, 32, 33 and 35 of the V H according to the numbering system of Kabat, wherein the protein prior to modification does not comprise a negatively charged amino acid at the positions in the V L and the V H;
Wooden terrace for outdoor use with ventilation, consisting at least of wooden material boards, between which gaps are formed, wherein in the gaps at least partially and/or in sections in each case a gap closure element for laying in gaps of wooden terraces and/or between wooden material boards in outdoor use with ventilation is accommodated under pretension, characterised in that the gap closure element leaves the gap open to such an extent that water can flow off unhindered, which gap closure element is designed as a zigzag-shaped strip section made of an elastic material.
An organic light emitting diode (OLED) device having enhanced light extraction, comprising: an upper waveguide structure that supports first guided modes and comprising a cathode, an anode with a lower surface, and an organic light-emitting semiconductor material interposed between the cathode and the anode; a lower waveguide structure interfaced with the upper waveguide structure and that supports second guided modes matched to the first guided modes, the lower waveguide structure comprising a substrate having an upper surface, a light-extraction waveguide distributed over the upper surface of the substrate, and a light-extraction matrix distributed over the light-extraction waveguide and the upper surface of the substrate; wherein the light-extraction matrix includes a rough upper surface that interfaces with the lower surface of the anode and that facilitates mode coupling from the first guided modes of the upper waveguide structure to the second guided modes of the lower waveguide structure while avoiding coupling from the first guided modes to surface plasmon polaritons; wherein light traveling as second guided modes in the light-extraction waveguide of the lower waveguide structure is redirected to exit the lower surface of the substrate by light-redirecting features of the lower waveguide structure; characterized in that the rough upper surface has a periodic component with a peak-to-valley amplitude A and a period P, wherein 0.5 μm ≤ P ≤ 2 μm, and wherein 20 nm ≤ A ≤ 60 nm; and the rough upper surface has a random component defined by a root-mean-square surface roughness σ 33, wherein 5 nm ≤ σ 33 ≤ 25 nm. an upper waveguide structure that supports first guided modes and comprising a cathode, an anode with a lower surface, and an organic light-emitting semiconductor material interposed between the cathode and the anode; a lower waveguide structure interfaced with the upper waveguide structure and that supports second guided modes matched to the first guided modes, the lower waveguide structure comprising a substrate having an upper surface, a light-extraction waveguide distributed over the upper surface of the substrate, and a light-extraction matrix distributed over the light-extraction waveguide and the upper surface of the substrate; wherein the light-extraction matrix includes a rough upper surface that interfaces with the lower surface of the anode and that facilitates mode coupling from the first guided modes of the upper waveguide structure to the second guided modes of the lower waveguide structure while avoiding coupling from the first guided modes to surface plasmon polaritons; wherein light traveling as second guided modes in the light-extraction waveguide of the lower waveguide structure is redirected to exit the lower surface of the substrate by light-redirecting features of the lower waveguide structure; characterized in that the rough upper surface has a periodic component with a peak-to-valley amplitude A and a period P, wherein 0.5 μm ≤ P ≤ 2 μm, and wherein 20 nm ≤ A ≤ 60 nm; and the rough upper surface has a random component defined by a root-mean-square surface roughness σ 33, wherein 5 nm ≤ σ 33 ≤ 25 nm.
An application comb for treating hair with a hair treatment preparation, comprising a grip portion and a plurality of teeth (10, 40) connected to the grip portion, at least two inner teeth adjacent to one another, which each have a ridge-shaped protrusion (20, 30) extending along one side of the application comb in the longitudinal direction of the inner teeth, which protrusions protrude perpendicularly to the longitudinal direction of the inner tooth over the contour thereof and each extend in the longitudinal direction of the associated inner tooth proceeding from the tooth base and extending up to between 0.3 and 0.8 times the length of the inner tooth, characterized in that the inner teeth are surrounded on both sides by outer teeth that are designed to be shorter than said inner teeth,
A reservoir tank mounting structure of a saddle riding vehicle comprising: a reservoir tank configured to store a hydraulic fluid of a brake apparatus; and an auxiliary machine case configured to accommodate an auxiliary machine mounted on the vehicle, wherein the auxiliary machine case has a tank supporting section at which the reservoir tank is supported, the tank supporting section is formed at a recessed section that is formed by having an outer surface of the auxiliary machine case recessed inward, and the tank supporting section includes an outer surface covering wall that is configured to cover an outer surface of the reservoir tank with a shape substantially conforming to an outer surface shape of the reservoir tank. a reservoir tank configured to store a hydraulic fluid of a brake apparatus; and an auxiliary machine case configured to accommodate an auxiliary machine mounted on the vehicle, wherein the auxiliary machine case has a tank supporting section at which the reservoir tank is supported, the tank supporting section is formed at a recessed section that is formed by having an outer surface of the auxiliary machine case recessed inward, and the tank supporting section includes an outer surface covering wall that is configured to cover an outer surface of the reservoir tank with a shape substantially conforming to an outer surface shape of the reservoir tank.
An electric motor, comprising: a frame; a stator provided with a stator core inserted into the frame in a contacted or coupled manner, and a stator coil; and a rotor rotatably disposed to be rotatable with respect to the stator, wherein the frame and the stator core have different thermal expansion coefficients from each other, and the frame has a smaller specific gravity and a greater thermal deformation value than the stator core, wherein an anti-separation unit is provided between the frame and the stator core to prevent the frame and the stator core from being spaced or separated from each other due to different levels of thermal deformation upon a temperature change, wherein the anti-separation unit includes: a protruding part (121,251,281) provided with anti-circumferential separation portions (123,253,283), and a coupling part (190,260,290) formed on the stator core to be coupled to an outside or an inside of the protruding part (121,251,281); the electric motor being characterized in that the frame includes a plurality of arcuate bases which are spaced to be arranged at predetermined intervals on the same circumference and have a cylindrical shape, the anti-circumferential separation portions (123,253,283) extend in a radial direction from ends of the bases adjacent to each other, respectively and are spaced along a circumferential direction to form buffer space therebetween, and the anti-separation unit includes a connecting portion (125,255,285) being spaced along the circumferential direction and connecting ends of the two adjacent anti-circumferential separation portions (123,253,283) along the circumferential direction. a frame; a stator provided with a stator core inserted into the frame in a contacted or coupled manner, and a stator coil; and a rotor rotatably disposed to be rotatable with respect to the stator,
A cycloduction measurement device, comprising: a blood vessel position recognition unit configured to recognize a position of a blood vessel in a sclera region in an eye image, and acquire information pertaining to the position of the blood vessel; and a first angle calculation unit configured to calculate an angle of cycloduction, on the basis of a first information pertaining to a position of a predetermined blood vessel acquired by the blood vessel position recognition unit when actually measuring cycloduction and a second information pertaining to the position of the predetermined blood vessel in a reference state (51; 63) characterized in that the blood vessel position recognition unit recognizes a periphery of an iris region in the eye image, and acquires position information of an end point at the peripheral side of the iris region of the blood vessel as information pertaining to the position of the blood vessel. a blood vessel position recognition unit configured to recognize a position of a blood vessel in a sclera region in an eye image, and acquire information pertaining to the position of the blood vessel; and a first angle calculation unit configured to calculate an angle of cycloduction, on the basis of a first information pertaining to a position of a predetermined blood vessel acquired by the blood vessel position recognition unit when actually measuring cycloduction and a second information pertaining to the position of the predetermined blood vessel in a reference state (51; 63) characterized in that the blood vessel position recognition unit recognizes a periphery of an iris region in the eye image, and acquires position information of an end point at the peripheral side of the iris region of the blood vessel as information pertaining to the position of the blood vessel.
A pharmaceutical composition comprising an LRP1 receptor agonist, wherein the LRP1 receptor agonist is selected from the group consisting of native or activated alpha-2-macroglobulin, a functional derivative or a functional fragment thereof and an antibody capable of binding to LRP1 receptor for use in the treatment of cancer selected from the group consisting of astrocytoma, glioblastoma, breast cancer, lung cancer, liver cancer, colon cancer, colorectal cancer, leukemia, sarcoma, mesotheleoma, prostate cancer, pancreatic cancer, cervical cancer, ovarian cancer, gastric cancer, esophageal cancer, head and neck cancer, melanoma, thyroid cancer and bone cancer, wherein said derivative is a protein with at least 80% sequence identity to said native or activated alpha-2-macroglobulin and/or is modified at the side chain or a free amino- or carboxy-terminus of an amino acid.