mhurhangee/ep-ind-claims huggingface dataset:
A method for preparing a substantially diastereomerically pure phosphorodiamidate morpholino oligomer comprising chiral phosphorous linkages, comprising: selecting substantially stereochemically pure phosphoramidochloridate morpholino monomers; and synthesizing a substantially diastereomerically pure phosphorodiamidate morpholino oligomer by stereospecific coupling of the selected substantially stereochemically pure phosphoramidochloridate morpholino monomers, wherein said stereospecific coupling is conducted in an aprotic solvent, in the presence of a non-nucleophilic tertiary amine or aromatic base, at a temperature of from 20 °C to 50 °C; wherein the substantially stereochemically pure phosphoramidochloridate morpholino monomers are obtained by separating a diastereomeric mixture of phosphoramidochloridate morpholino monomers into substantially stereochemically pure phosphoramidochloridate monomers, and wherein substantially stereochemically pure denotes enantiomers or diastereoisomers that are in enantiomeric or diastereomeric excess, respectively, equal to or greater than 87%, and substantially diastereomerically pure denotes diastereoisomers that are in diastereomeric excess equal to or greater than 87%. selecting substantially stereochemically pure phosphoramidochloridate morpholino monomers; and synthesizing a substantially diastereomerically pure phosphorodiamidate morpholino oligomer by stereospecific coupling of the selected substantially stereochemically pure phosphoramidochloridate morpholino monomers, wherein said stereospecific coupling is conducted in an aprotic solvent, in the presence of a non-nucleophilic tertiary amine or aromatic base, at a temperature of from 20 °C to 50 °C; wherein the substantially stereochemically pure phosphoramidochloridate morpholino monomers are obtained by separating a diastereomeric mixture of phosphoramidochloridate morpholino monomers into substantially stereochemically pure phosphoramidochloridate monomers, and wherein substantially stereochemically pure denotes enantiomers or diastereoisomers that are in enantiomeric or diastereomeric excess, respectively, equal to or greater than 87%, and substantially diastereomerically pure denotes diastereoisomers that are in diastereomeric excess equal to or greater than 87%.
A method of enabling measurements for handling of a device-to-device, D2D, side link in a cellular system, the method being performed in a first D2D capable device and comprising: - providing, to a second D2D device, information relating to a first transmission power of a first transmission between the first D2D device and the second D2D device, wherein the first transmission power is used by the first D2D capable device, wherein the information relating to the first transmission power comprises an indication of a power change of the first transmission power of the first transmission, and - receiving, from the second D2D device, a measurement report based on the provided information relating to the first transmission power. - providing, to a second D2D device, information relating to a first transmission power of a first transmission between the first D2D device and the second D2D device, wherein the first transmission power is used by the first D2D capable device, wherein the information relating to the first transmission power comprises an indication of a power change of the first transmission power of the first transmission, and - receiving, from the second D2D device, a measurement report based on the provided information relating to the first transmission power.
A drive device comprising: - a screw-and-nut system comprising a threaded rod and a first nut (20; 21) that is connected to the threaded rod by means of a screw connection; - a gearset, allowing a rotational movement to be transmitted to the threaded rod, the gearset comprising a first toothed wheel and a second toothed wheel engaged with the first toothed wheel; characterized in that the drive device comprises: - a set of stops (31, 32) comprising a first stop connected to the first wheel rotating about an axis of rotation of the first wheel and a second stop connected to the second toothed wheel rotating about an axis of rotation of the second wheel, the first stop and the second stop being configured and arranged to butt against one another so as to limit an angular travel of the threaded rod at a first angular position in a first direction. - a screw-and-nut system comprising a threaded rod and a first nut (20; 21) that is connected to the threaded rod by means of a screw connection; - a gearset, allowing a rotational movement to be transmitted to the threaded rod, the gearset comprising a first toothed wheel and a second toothed wheel engaged with the first toothed wheel; - a set of stops (31, 32) comprising a first stop connected to the first wheel rotating about an axis of rotation of the first wheel and a second stop connected to the second toothed wheel rotating about an axis of rotation of the second wheel, the first stop and the second stop being configured and arranged to butt against one another so as to limit an angular travel of the threaded rod at a first angular position in a first direction.
A navigation device comprising: a map data storage unit for storing map data; a resolution conversion unit for converting the resolution of the map data acquired from the map data storage unit; and a display unit having a predetermined display area for displaying a map based on the map data with its resolution converted, wherein on a primary screen, on which a wide-area map is displayed in the entire display area of the display unit, a secondary screen presenting a detailed map having its resolution lowered and being reduced in size from that of the primary screen is displayed, wherein the map data comprises polygon data, and wherein the resolution conversion unit comprises a coordinate processing unit which carries out the resolution conversion and a coordinate transformation of map data in accordance with an equation for calculating the transformation to a vertex coordinate Xs, Ys on the secondary screen, the equation being expressed by Xs = OffsetX + Xm / Rr, Ys = OffsetY + Ym / Rr wherein a ratio of the resolution of the primary screen to that of the secondary screen is represented by Rr, the vertex coordinate on the primary screen is represented by Xm, Ym, and the area of the secondary screen being represented by OffsetX, Offset Y. a map data storage unit for storing map data; a resolution conversion unit for converting the resolution of the map data acquired from the map data storage unit; and a display unit having a predetermined display area for displaying a map based on the map data with its resolution converted, wherein on a primary screen, on which a wide-area map is displayed in the entire display area of the display unit, a secondary screen presenting a detailed map having its resolution lowered and being reduced in size from that of the primary screen is displayed, wherein the map data comprises polygon data, and wherein the resolution conversion unit comprises a coordinate processing unit which carries out the resolution conversion and a coordinate transformation of map data in accordance with an equation for calculating the transformation to a vertex coordinate Xs, Ys on the secondary screen, the equation being expressed by Xs = OffsetX + Xm / Rr, Ys = OffsetY + Ym / Rr wherein a ratio of the resolution of the primary screen to that of the secondary screen is represented by Rr, the vertex coordinate on the primary screen is represented by Xm, Ym, and the area of the secondary screen being represented by OffsetX, Offset Y.
A source resonator for wirelessly transmitting power to a target device comprising: a magnetic field distribution adjusting unit that is configured to adjust the magnetic field generated by the source resonator, wherein the magnetic field distribution adjusting unit comprises at least one sub-resonator positioned inside the source resonator, so as to adjust the intensity of the magnetic field inside of the source resonator to be substantially uniform, characterized in that the magnetic field distribution adjusting unit comprises at least one shield layer, induces a substantially uniform distribution of the magnetic field generated inside the source resonator by adjusting the length, width, thickness, or any combination thereof of the at least one shield layer, and adjusts that at least one shield layer to compensate for a parasitic capacitance generated between the source resonator and a target resonator. a magnetic field distribution adjusting unit that is configured to adjust the magnetic field generated by the source resonator, wherein the magnetic field distribution adjusting unit comprises at least one sub-resonator positioned inside the source resonator, so as to adjust the intensity of the magnetic field inside of the source resonator to be substantially uniform, characterized in that the magnetic field distribution adjusting unit comprises at least one shield layer, induces a substantially uniform distribution of the magnetic field generated inside the source resonator by adjusting the length, width, thickness, or any combination thereof of the at least one shield layer, and adjusts that at least one shield layer to compensate for a parasitic capacitance generated between the source resonator and a target resonator.
Display device adapted to receive image data, comprising a display layer, a controllable reflector layer that has controllable reflectivity, a light source generating light that enters a light distribution assembly, wherein the light distribution assembly is arranged between the display layer and the reflector layer, wherein the display device further comprises - a first controller adapted to generate, based on the image data, display data to drive the display layer, and - a second controller adapted to convert the input image data to a greyscale image with the number of grey levels adapted according to the bit depth of the controllable reflector layer, wherein the second controller comprises a two-dimensional filter adapted to receive said greyscale image, and is adapted to generate, based on the output of the two-dimensional filter, a control signal to control the reflectivity of the controllable reflector layer, characterized in that the two-dimensional filter is a high-pass filter that enhances edges between bright and dark areas of the image data, to at least partially compensate the degradation of the edges induced by the intrinsic low pass characteristic of the light distribution assembly. - a first controller adapted to generate, based on the image data, display data to drive the display layer, and - a second controller adapted to convert the input image data to a greyscale image with the number of grey levels adapted according to the bit depth of the controllable reflector layer, wherein the second controller comprises a two-dimensional filter adapted to receive said greyscale image, and is adapted to generate, based on the output of the two-dimensional filter, a control signal to control the reflectivity of the controllable reflector layer, characterized in that the two-dimensional filter is a high-pass filter that enhances edges between bright and dark areas of the image data, to at least partially compensate the degradation of the edges induced by the intrinsic low pass characteristic of the light distribution assembly.
A method for assembling a solar cell structure comprising the steps of: providing a silicon carrier having a front side and a back side; providing a solar cell having a front side and a back side, wherein said back side of said solar cell includes a first metallization layer connected thereto; forming a P-N junction in said carrier such that said carrier includes a P-type portion and an N-type portion; forming a second metallization layer on said front side of said carrier, said second metallization layer being electrically coupled to said N-type portion; connecting said first metallization layer to said second metallization layer to form a metal-to-metal bond therebetween; and electrically coupling said front side of said solar cell to said P-type portion; the method being characterized in that said front side of said solar cell includes a temporary substrate connected thereto, and said method further comprises the step of removing said temporary substrate from said front side of said solar cell after said connecting step. providing a silicon carrier having a front side and a back side; providing a solar cell having a front side and a back side, wherein said back side of said solar cell includes a first metallization layer connected thereto; forming a P-N junction in said carrier such that said carrier includes a P-type portion and an N-type portion; forming a second metallization layer on said front side of said carrier, said second metallization layer being electrically coupled to said N-type portion; connecting said first metallization layer to said second metallization layer to form a metal-to-metal bond therebetween; and electrically coupling said front side of said solar cell to said P-type portion; the method being characterized in that said front side of said solar cell includes a temporary substrate connected thereto, and said method further comprises the step of removing said temporary substrate from said front side of said solar cell after said connecting step.
A microcapsule comprising a capsule core and a polymeric shell, wherein the core essentially contains only hydrophobic components and the shell comprises in polymerized form A) at least one poly(ester-urethane) containing at least 2 isocyanate groups, obtainable by reacting at least one polyester-polyol containing at least 2 OH groups with at least one polyisocyanate containing at least 2 NCO groups, and B1) at least one polymeric polyamine having a weight average molecular weight of at least 300 g/mol and containing at least 3 amino groups reactive towards NCO groups, wherein the hydrophobic component comprises a pesticide. A) at least one poly(ester-urethane) containing at least 2 isocyanate groups, obtainable by reacting at least one polyester-polyol containing at least 2 OH groups with at least one polyisocyanate containing at least 2 NCO groups, and B1) at least one polymeric polyamine having a weight average molecular weight of at least 300 g/mol and containing at least 3 amino groups reactive towards NCO groups, wherein the hydrophobic component comprises a pesticide.
An agricultural apparatus comprising an agricultural vehicle and a number of work units (6,8,10) suitable for cutting a standing crop, the work units (6,8,10) being connected to the agricultural vehicle, the number of work units (6,8,10) including a front work unit and two lateral work units (8,10) located behind and to the sides of the front work unit, each of the work units (6,8,10) configured to deposit the cut crop as a swath, each of the lateral work units (8,10) being supported from a central chassis by a hydraulic system, the agricultural apparatus further comprising a control unit and a plurality of sensors (36,38,40), characterised in that the sensors are configured to determine a speed of the agricultural vehicle, a speed of operation of each lateral work unit (8,10) and a relief pressure in the hydraulic system of each lateral work unit (8,10), the control unit being configured to receive inputs from the plurality of sensors (36,38,40), compare the values for a desired vehicle speed or speed of operation of the lateral work units (8,10) and adjusting the pressure relief in the hydraulic system based on this comparison, wherein the agricultural apparatus further includes a further plurality of sensors (42,44) to detect an overload condition in each of the lateral work units (8,10), the control unit being configured to compare a speed of operation of each lateral work unit (8,10) before and after an overload protection and the speed of the agricultural vehicle and to adjust the speed of the agricultural vehicle based on this comparison. the sensors are configured to determine a speed of the agricultural vehicle, a speed of operation of each lateral work unit (8,10) and a relief pressure in the hydraulic system of each lateral work unit (8,10), the control unit being configured to receive inputs from the plurality of sensors (36,38,40), compare the values for a desired vehicle speed or speed of operation of the lateral work units (8,10) and adjusting the pressure relief in the hydraulic system based on this comparison, wherein the agricultural apparatus further includes a further plurality of sensors (42,44) to detect an overload condition in each of the lateral work units (8,10), the control unit being configured to compare a speed of operation of each lateral work unit (8,10) before and after an overload protection and the speed of the agricultural vehicle and to adjust the speed of the agricultural vehicle based on this comparison.
A drug applicator for a system for ultrasound-enhanced transscleral delivery of at least one drug to a target site in an intraocular space, the system comprising a signal generating unit operationally connected to an ultrasound transducer, wherein the drug applicator: i) comprises at least one space configured to hold the drug, ii) is made from a low ultrasound attenuation material having an ultrasound attenuation of less than 10dB/(MHz cm), iii) is formed from a soft and elastic material and configured to provide less than 10% ultrasound loss coupling of the system to the sclera, and iv) is configured to be mechanically coupled to the system and further configured to be coupled by a mechanical coupling to the ultrasound transducer with ultrasound loss of less than 20%; and wherein the ultrasound transducer is configured to emit an ultrasound wave form in at least one application cycle, the application cycle comprising at least one ultrasound emitting event with a time duration TA and a waiting period with a time duration TW, wherein the at least one space has at least one opening at a surface designated for coupling with the sclera. wherein the drug applicator: i) comprises at least one space configured to hold the drug, ii) is made from a low ultrasound attenuation material having an ultrasound attenuation of less than 10dB/(MHz cm), iii) is formed from a soft and elastic material and configured to provide less than 10% ultrasound loss coupling of the system to the sclera, and iv) is configured to be mechanically coupled to the system and further configured to be coupled by a mechanical coupling to the ultrasound transducer with ultrasound loss of less than 20%; and i) comprises at least one space configured to hold the drug, ii) is made from a low ultrasound attenuation material having an ultrasound attenuation of less than 10dB/(MHz cm), iii) is formed from a soft and elastic material and configured to provide less than 10% ultrasound loss coupling of the system to the sclera, and iv) is configured to be mechanically coupled to the system and further configured to be coupled by a mechanical coupling to the ultrasound transducer with ultrasound loss of less than 20%; and wherein the ultrasound transducer is configured to emit an ultrasound wave form in at least one application cycle, the application cycle comprising at least one ultrasound emitting event with a time duration TA and a waiting period with a time duration TW, wherein the at least one space has at least one opening at a surface designated for coupling with the sclera.
A biocompatible cross-linked biopolymer for use for tissue augmentation for improvement of the aesthetic appearance of an anatomical feature of an individual wherein said biopolymer is based on hyaluronic acid cross-linked with urea.
A compound for use in a method of treating idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia, Behçet's disease, Cogan's syndrome, giant cell arteritis, polymyalgia rheumatica, Takayasu's arteritis, Buerger's disease (thromboangiitis obliterans), central nervous system vasculitis, Kawasaki disease, polyarteritis nodosa, Churg-Strauss syndrome, mixed cryoglobulinemia vasculitis (essential or hepatitis C virus -induced), Henoch-Schönlein purpura, hypersensitivity vasculitis, microscopic polyangiitis, Wegener's granulomatosis, anti-neutrophil cytoplasm antibody associated (ANCA) systemic vasculitis (AASV), pemphigus, membranous nephropathy, chronic lymphocytic leukemia, hairy cell leukemia, Mantle cell lymphoma, small lymphocytic lymphoma, follicular lymphoma, lymphoplasmacytic lymphoma, extranodal marginal zone lymphoma, activated B-cell like diffuse large B cell lymphoma, or germinal center B cell diffuse large B cell lymphoma in a patient, wherein the compound is of Formula IV: or a pharmaceutically acceptable salt thereof, wherein: G is NH, n is 1, and V is O; or G is NH, n is 0, and V is CH 2; or G is O, n is 0 and V is NH; R 2 is C 1-6 alkyl or C 1-6 haloalkyl; R 4 is halo, OH, CN, C 1-4 alkyl, C 1-4 haloalkyl, C 1-4 alkoxy, or C 1-4 haloalkoxy; R 5 is halo, OH, CN, C 1-4 alkyl, C 1-4 haloalkyl, C 1-4 alkoxy, or C 1-4 haloalkoxy. G is NH, n is 1, and V is O; or G is NH, n is 0, and V is CH 2; or G is O, n is 0 and V is NH; R 2 is C 1-6 alkyl or C 1-6 haloalkyl; R 4 is halo, OH, CN, C 1-4 alkyl, C 1-4 haloalkyl, C 1-4 alkoxy, or C 1-4 haloalkoxy; R 5 is halo, OH, CN, C 1-4 alkyl, C 1-4 haloalkyl, C 1-4 alkoxy, or C 1-4 haloalkoxy.
Heat exchanger for gas, particularly for exhaust gases from an engine, comprising a core bundle of tubes arranged inside a shell defining a gas inlet and outlet, the said tubes being intended for the circulation of the gases with a view to an exchange of heat with a cooling liquid and the said tubes being distributed in at least one column of several rows defining several spaces between the rows, and comprising an inlet pipe and an outlet pipe for cooling liquid which are connected to the shell, the said exchanger comprising a bypass duct incorporated into the shell and capable of making the spaces defined between the rows of tubes situated facing the said duct communicate with one of the cooling liquid pipes, so as to improve the distribution of the cooling liquid, the exchanger comprising at least one through-orifice intended to allow controlled passage of the cooling liquid between the inside of the shell and the bypass duct, characterized in that the said duct is associated with a shut-off plate coupled to the shell in the interior space situated facing the said duct, the said shut-off plate comprising the said through-orifice.