mhurhangee/ep-ind-claims huggingface dataset:
An antibody having specificity for B and T lymphocyte attenuator (BTLA) characterized in that i. it does not block the binding of HVEM to BTLA, and ii. it increases the proliferation of Vγ9VδT cells and wherein said antibody is either i. an antibody having a heavy chain comprising the H-CDR1 as defined by the sequence ranging from the amino acid residue at position 31 to the amino acid residue at position 35 in SEQ ID NO:1; the H-CDR2 as defined by the sequence ranging from the amino acid residue at position 50 to the amino acid residue at position 65 in SEQ ID NO:1; the H-CDR3 as defined by the sequence ranging from the amino acid residue at position 98 to the amino acid residue at position 109 in SEQ ID NO:1; the L-CDR1 as defined by the sequence ranging from the amino acid residue at position 24 to the amino acid residue at position 40 in SEQ ID NO:2; the L-CDR2 as defined by the sequence ranging from the amino acid residue at position 56 to the amino acid residue at position 62 in SEQ ID NO:2; and, the L-CDR3 as defined by the sequence ranging from the amino acid residue at position 95 to the amino acid residue at position 102 in SEQ ID NO:2; or, ii. a functional variant of a parent antibody as defined in (i) having CDR variant sequences which differ from corresponding CDR sequences of said parent antibody from only 1 substitution by conservative amino acid residue replacement. i. it does not block the binding of HVEM to BTLA, and ii. it increases the proliferation of Vγ9VδT cells i. an antibody having a heavy chain comprising the H-CDR1 as defined by the sequence ranging from the amino acid residue at position 31 to the amino acid residue at position 35 in SEQ ID NO:1; the H-CDR2 as defined by the sequence ranging from the amino acid residue at position 50 to the amino acid residue at position 65 in SEQ ID NO:1; the H-CDR3 as defined by the sequence ranging from the amino acid residue at position 98 to the amino acid residue at position 109 in SEQ ID NO:1; the L-CDR1 as defined by the sequence ranging from the amino acid residue at position 24 to the amino acid residue at position 40 in SEQ ID NO:2; the L-CDR2 as defined by the sequence ranging from the amino acid residue at position 56 to the amino acid residue at position 62 in SEQ ID NO:2; and, the L-CDR3 as defined by the sequence ranging from the amino acid residue at position 95 to the amino acid residue at position 102 in SEQ ID NO:2; or, ii. a functional variant of a parent antibody as defined in (i) having CDR variant sequences which differ from corresponding CDR sequences of said parent antibody from only 1 substitution by conservative amino acid residue replacement.
Constant pressure or pressureless filling machine of circulating design for the sterile filling of bottles or similar containers with a liquid filling material, with a rotor capable of being driven about a vertical machine axis, with a plurality of filling elements provided at the rotor with, in each case, a discharge opening (1.1) for the discharge of the liquid filling material into the respective container, wherein the filling elements are accommodated at least with their discharge openings (1.1), and the containers are accommodated at least with a container section comprising the respective container opening (2.2), in a sterile chamber, with a tank which is connected to each filling element via a product line, and forms a partial chamber (9.1) serving to accommodate the liquid filling product, and a gas chamber (9.2) located above said partial chamber, to which can be applied a sterile gaseous and/or vaporous medium, and with at least one pressure equalization connection (12, 17, 19; 14, 23, 24) connecting the gas chamber (9.2) of the tank with the sterile chamber characterised in that the sterile chamber is an annular chamber surrounding the vertical machine axis, in which all the filling elements are arranged in common at least with their discharge openings (1.1), and that, with the filling drive running, the at least one pressure equalization connection (12, 17, 19; 14, 23, 24) between the gas chamber (9.2) of the tank and the sterile chamber is opened, such that a constant gas pressure pertains between the tank and the sterile chamber, and therefore the influence of pressure fluctuations in the gas chamber of the tank on the filling rate is eliminated.
An electric surgical stapler, comprising: a handle, including a handle body, a driving motor and a control unit for controlling the driving motor to operate; a working head, including an anvil, a cartridge, a closing mechanism, a firing mechanism, a housing for accommodating the closing mechanism and the firing mechanism, a closing limit switch configured to transmit information of a closing stroke of the closing mechanism to the control unit, and a pressure sensor configured to transmit a pressure value applied to a squeezed tissue during the closing stroke to the control unit; wherein the closing mechanism includes a first linear motion component configured to drive the anvil to move or drive the cartridge to move; the closing limit switch is triggered when the first linear motion component moves to a closing position within a preset range; wherein the control unit is configured to transmit an instruction of controlling the driving motor to drive the firing mechanism to move, when the closing limit switch is triggered and the pressure value transmitted by the pressure sensor meets a preset standard. a handle, including a handle body, a driving motor and a control unit for controlling the driving motor to operate; a working head, including an anvil, a cartridge, a closing mechanism, a firing mechanism, a housing for accommodating the closing mechanism and the firing mechanism, a closing limit switch configured to transmit information of a closing stroke of the closing mechanism to the control unit, and a pressure sensor configured to transmit a pressure value applied to a squeezed tissue during the closing stroke to the control unit; wherein the closing mechanism includes a first linear motion component configured to drive the anvil to move or drive the cartridge to move; the closing limit switch is triggered when the first linear motion component moves to a closing position within a preset range; wherein the control unit is configured to transmit an instruction of controlling the driving motor to drive the firing mechanism to move, when the closing limit switch is triggered and the pressure value transmitted by the pressure sensor meets a preset standard.
A nucleic acid molecule comprising a nucleic acid sequence that confers resistance to inhibition by one or more acetolactate synthase herbicides, wherein said sequence comprises: (i) a sequence comprising The Institute for Genomic Research Transcript Assembly number TA3960_4558, which has the sequence: or a sequence at least 95% homologous thereto, and which further comprises the nucleotide substitutions of guanine substituted with adenine at position 1641 and guanine substituted with thymine at position 1684; or (ii) an acetolactate synthase resistance gene as found in ATCC No. PTA-7999, or a sequence at least 95% homologous thereto which further comprises the nucleotide substitutions of guanine substituted with adenine at position 1641 of TA3960_4558 the sequence of which is shown above under (i) and guanine substituted with thymine at position 1684 of TA3960_4558. (i) a sequence comprising The Institute for Genomic Research Transcript Assembly number TA3960_4558, which has the sequence: or a sequence at least 95% homologous thereto, and which further comprises the nucleotide substitutions of guanine substituted with adenine at position 1641 and guanine substituted with thymine at position 1684; or (ii) an acetolactate synthase resistance gene as found in ATCC No. PTA-7999, or a sequence at least 95% homologous thereto which further comprises the nucleotide substitutions of guanine substituted with adenine at position 1641 of TA3960_4558 the sequence of which is shown above under (i) and guanine substituted with thymine at position 1684 of TA3960_4558.
A hold open rod comprising: an inner member; an outer member configured to have the inner member slide in and out of the outer member; and a noncircular dampening member arranged on the inner member, the noncircular dampening member being configured to dampen movement of at least one of the following: the inner member and the outer member, the hold open rod characterized wherein: the inner member and the outer member are configured with a rattle space (102, 104) adjacent the noncircular dampening member; and the noncircular dampening member is configured to rotate about the inner member to dampen vibration. an inner member; an outer member configured to have the inner member slide in and out of the outer member; and a noncircular dampening member arranged on the inner member, the noncircular dampening member being configured to dampen movement of at least one of the following: the inner member and the outer member, the hold open rod characterized wherein: the inner member and the outer member are configured with a rattle space (102, 104) adjacent the noncircular dampening member; and the noncircular dampening member is configured to rotate about the inner member to dampen vibration. the inner member and the outer member are configured with a rattle space (102, 104) adjacent the noncircular dampening member; and the noncircular dampening member is configured to rotate about the inner member to dampen vibration.
A method for wireless communications by a network entity (no) comprising: determining one or more bandwidth parts, BWPs, within a maximum channel bandwidth for radio link monitoring, RLM; and transmitting, to a user equipment, UE, an RS configuration indicating the one or more BWPs to monitor for one or more RSs. determining one or more bandwidth parts, BWPs, within a maximum channel bandwidth for radio link monitoring, RLM; and transmitting, to a user equipment, UE, an RS configuration indicating the one or more BWPs to monitor for one or more RSs.
A shell-and-tube type reactor for carrying out catalytic gas phase reactions and comprising a contact tube bundle through which the respective reaction gas mixture flows and which includes a catalyst filling, extends between a gas-inlet-side tubesheet and a gas-outlet-side tubesheet and is flushed with a heat carrier within a surrounding reactor shell and comprising gas inlet and gas outlet hoods (2; 60) spanning the two tubesheets for supplying the respective process gas to the contact tubes and for discharging the reacted process gas from the contact tubes and comprising a process gas feed conduit for introducing the process gas into the gas inlet hood, characterized in that the process gas feed conduit includes a first portion for taking up a non-explosive process gas and behind the same in the flow direction of the process gas a second portion with a feed point (176, 178; 192) for taking up an explosive process gas; the process gas feed conduit in the first portion includes a check valve assembly, a depressurizing volume in the first portion is arranged downstream of the check valve assembly in the direction of flow, wherein the depressurizing volume is at least partly formed by a chamber accommodating the check valve assembly; and the check valve assembly and the gas-inlet-side tubesheet as well as all parts present between the same, which bear the process gas pressure, have a strength designed for the maximum pressure that occurs during the explosion or detonation of the process gas.
A turbine diaphragm system comprising: a diaphragm surrounding a rotor of the turbine, the rotor comprising plurality of rotor blades; an outer ring disposed about the rotor; a set of nozzles disposed circumferentially about an interior of the outer ring and connected to the diaphragm, the set of nozzles extending radially inboard; an inner ring radially inboard of the outer ring and connected to the set of nozzles; characterized in that it comprises a device which is connected to an inner surface of the outer ring and extending circumferentially about the outer ring covering a portion of the set of nozzles, the device comprising a base connected to the diaphragm and a radial portion connected to the base and extending radially inboard from the base toward the rotor of the turbine, the radial portion oriented to contact and guide a leakage flow of working fluid between the diaphragm and tips of the rotor blades to a primary working fluid path of the turbine at an angle that is substantially complementary to the working fluid flowpath, whereby the radial portion includes a first set of ridges (188, 280, 388) disposed on an upstream surface, the first set of ridges (188, 280, 388) oriented substantially radially and extending axially upstream relative the upstream surface. a diaphragm surrounding a rotor of the turbine, the rotor comprising plurality of rotor blades; an outer ring disposed about the rotor; a set of nozzles disposed circumferentially about an interior of the outer ring and connected to the diaphragm, the set of nozzles extending radially inboard; an inner ring radially inboard of the outer ring and connected to the set of nozzles; characterized in that it comprises a device which is connected to an inner surface of the outer ring and extending circumferentially about the outer ring covering a portion of the set of nozzles, the device comprising a base connected to the diaphragm and a radial portion connected to the base and extending radially inboard from the base toward the rotor of the turbine, the radial portion oriented to contact and guide a leakage flow of working fluid between the diaphragm and tips of the rotor blades to a primary working fluid path of the turbine at an angle that is substantially complementary to the working fluid flowpath, whereby the radial portion includes a first set of ridges (188, 280, 388) disposed on an upstream surface, the first set of ridges (188, 280, 388) oriented substantially radially and extending axially upstream relative the upstream surface.
A light emitting device, comprising: a substrate having a main surface; an inner portion provided on said main surface and containing a semiconductor light emitting element that emits primary light and a fluorescent particle that absorbs a part of the primary light and emits secondary light, said inner portion being formed of a transparent resin or glass; and an outer portion having a refractive index n and covering said inner portion, said outer portion being formed of a transparent resin or glass, wherein said outer portion has an outer circumferential surface that forms a boundary between the outer portion and the atmosphere, wherein the outer circumferential surface forms an outer spherical cap with a radius of its forming sphere R, and wherein a minimum circumference that includes the overall of said inner portion and is concentric with said outer spherical cap has a radius r, wherein the origin of the radius R to said spherical cap and of the radius r to the minimum circumference is at the main surface of the substrate, and wherein said inner portion is a phosphor layer containing said fluorescent particle, and said phosphor layer is provided to completely fill the space between said semiconductor light emitting element and said outer portion on said main surface, and characterized in that the radius R to said outer spherical cap and the radius r to the minimum circumference satisfy the relationship R>r∗n. a substrate having a main surface; an inner portion provided on said main surface and containing a semiconductor light emitting element that emits primary light and a fluorescent particle that absorbs a part of the primary light and emits secondary light, said inner portion being formed of a transparent resin or glass; and an outer portion having a refractive index n and covering said inner portion, said outer portion being formed of a transparent resin or glass, wherein said outer portion has an outer circumferential surface that forms a boundary between the outer portion and the atmosphere, wherein the outer circumferential surface forms an outer spherical cap with a radius of its forming sphere R, and wherein a minimum circumference that includes the overall of said inner portion and is concentric with said outer spherical cap has a radius r, wherein the origin of the radius R to said spherical cap and of the radius r to the minimum circumference is at the main surface of the substrate, and wherein said inner portion is a phosphor layer containing said fluorescent particle, and said phosphor layer is provided to completely fill the space between said semiconductor light emitting element and said outer portion on said main surface, and characterized in that the radius R to said outer spherical cap and the radius r to the minimum circumference satisfy the relationship R>r∗n.
A shoe comprising: - a sole having an outsole and an insole; - a high heel configured below the outsole, and - a shank embedded between the insole and the outsole, the shank extending along a longitudinal direction of the sole, and comprising: - a front portion, and - a heel portion having a depression configured to accommodate a user's heel and an upper affixed to a top portion of the sole, characterised in that the shank further comprises a lateral ridge extending across the shank immediately in front of the heel portion and the front portion sloping downward from the lateral ridge. - a sole having an outsole and an insole; - a high heel configured below the outsole, and - a shank embedded between the insole and the outsole, - a front portion, and - a heel portion having a depression configured to accommodate a user's heel and an upper affixed to a top portion of the sole, characterised in that
Control device for an internal combustion engine comprising a suction duct, an exhaust gas recirculation duct opening into the suction duct, a housing in which the suction duct and at least one port of the exhaust gas recirculation duct are formed, a shaft serving as a rotary axis, the shaft being arranged in the housing upstream of the port of the exhaust gas recirculation duct, with respect to the air flow, and outside of the flow cross section, and which shaft is arranged perpendicularly to the center axes (20, 34) of the suction duct and the exhaust gas recirculation duct, a control body which is fastened eccentrically on the shaft and via which the control body can be turned in the suction duct, a first valve seat on which the control body rests in a first end position in which the control body closes the suction duct, a second valve seat on which the control body rests in a second end position in which the control body closes the exhaust gas recirculation duct, characterized in that a tubular housing part is beveled at the downstream end, wherein the downstream end serves as the first valve seat by which a plane is spanned which includes an angle of 70° to 80° with respect to the centre axis of the suction duct.
Aqueous extraction process for obtaining a tannin extract isolated from grapes which process comprises using a source of tannins, preparing an aqueous solution of a polyphenol-solubilising agent and performing a tannin extraction step in a reactor that comprises the source of tannins and the prepared aqueous solution at a given pressure and temperature, characterised in that: - the source of tannins consists of grape whole-seeds, - the polyphenol-solubilising agent is selected from urea, sodium hydroxide and a compound containing the SOs group, and its concentration in the aqueous solution ranges between 1% and 15% by weight with respect to the weight of the grape whole-seeds, and - a single extraction step performed in a one-pot by using an autoclave reactor at a pressure ranging between 1 and 6 atmospheres, and a temperature ranging between 80°C and 160°C, and - optionally, concentrating the extract by evaporation, to obtain a concentrated tannin extract isolated from grape whole-seeds, and/or spray drying, to obtain a solid tannin extract isolated from grape whole-seeds. - the source of tannins consists of grape whole-seeds, - the polyphenol-solubilising agent is selected from urea, sodium hydroxide and a compound containing the SOs group, and its concentration in the aqueous solution ranges between 1% and 15% by weight with respect to the weight of the grape whole-seeds, and - a single extraction step performed in a one-pot by using an autoclave reactor at a pressure ranging between 1 and 6 atmospheres, and a temperature ranging between 80°C and 160°C, and - optionally, concentrating the extract by evaporation, to obtain a concentrated tannin extract isolated from grape whole-seeds, and/or spray drying, to obtain a solid tannin extract isolated from grape whole-seeds.
A cake mix comprising: i. sugar; ii. flour; and iii. pea protein and rapeseed protein; wherein the ratio of pea protein to rapeseed protein is within the range of 61:39 to 94:6 w/w preferably 71:29 to 94:6 w/w. i. sugar; ii. flour; and iii. pea protein and rapeseed protein;
A method for providing scalability and redundancy in a blade cluster of a telecommunication system, the blade cluster acting towards the telecommunication system as a single Mobile Switching Center, MSC, and comprising a plurality of server blades offering MSC-Server functionality, the method comprising the steps of: • receiving, from a radio access node, a message related to a subscriber, wherein the received message comprises a unique subscriber identifier; • determining, by use of the unique subscriber identifier, a first value; • determining, by use of said first value, a first server blade of said blade cluster; • determining, by use of the unique subscriber identifier, a second value; • determining, by use of said second value, a second server blade of said blade cluster, wherein for determining said second server blade, said first server blade is excluded from being determined; • checking availability of the determined said first and said second server blades; • after said first and said second server blades have been determined and are available, checking which one of said first and said second server blades is active; and • forwarding said message towards said first server blade if said first server blade is active, wherein if said first server blade is inactive and said second server blade is active, forwarding said message towards said second server blade, and wherein said second server blade serves the subscriber when said first server blade is unavailable. • receiving, from a radio access node, a message related to a subscriber, wherein the received message comprises a unique subscriber identifier; • determining, by use of the unique subscriber identifier, a first value; • determining, by use of said first value, a first server blade of said blade cluster; • determining, by use of the unique subscriber identifier, a second value; • determining, by use of said second value, a second server blade of said blade cluster, wherein for determining said second server blade, said first server blade is excluded from being determined; • checking availability of the determined said first and said second server blades; • after said first and said second server blades have been determined and are available, checking which one of said first and said second server blades is active; and • forwarding said message towards said first server blade if said first server blade is active, wherein if said first server blade is inactive and said second server blade is active, forwarding said message towards said second server blade, and