A system configured to generate a simulated pressurized flow of gas including a first gas having a partial pressure that varies in a predetermined manner to simulate a respiratory gas flow of a subject, the system comprising: electronic storage adapted to store a gas flow data set that comprises a recorded plot of a pressurized flow of gas as a function of time representative of a respiratory gas flow of a subject exhibiting a respiratory phenomenon, state, event, or other respiratory circumstance, the gas flow data set specifying partial pressure of a first gas in the recorded plot of the pressurized flow of gas as a function of time; an outlet configured to emit a simulated pressurized flow of gas; a flow generator adapted to generate the simulated pressurized flow of gas that simulates the respiratory gas flow of the subject, wherein the flow generator comprises: a baseline valve assembly configured to control a flow rate of a baseline gas through the outlet; and a first valve assembly configured to control a flow rate of the first gas through the outlet; and one or more processors configured to execute processing modules, wherein the processing modules comprise: a baseline flow rate module configured to obtain a baseline flow rate for the baseline gas during generation of the simulated pressurized flow of gas, wherein the baseline flow rate is a function of a parameter of the partial pressure specified for the first gas from the gas flow data set; a first flow rate module configured to determine a first flow rate for the first gas based on the partial pressure specified for the first gas from the gas flow data set such that the first flow rate changes over time in accordance with the partial pressure specified for the first gas from the gas flow data set; and a control module configured to control the flow generator to generate the simulated pressurized flow of gas that simulates the respiratory gas flow of the subject represented by the gas flow data set, including controlling the baseline valve assembly to deliver the baseline gas to the outlet at the baseline flow rate and controlling the first valve assembly to deliver the first gas to the outlet at the first flow rate. electronic storage adapted to store a gas flow data set that comprises a recorded plot of a pressurized flow of gas as a function of time representative of a respiratory gas flow of a subject exhibiting a respiratory phenomenon, state, event, or other respiratory circumstance, the gas flow data set specifying partial pressure of a first gas in the recorded plot of the pressurized flow of gas as a function of time; an outlet configured to emit a simulated pressurized flow of gas; a flow generator adapted to generate the simulated pressurized flow of gas that simulates the respiratory gas flow of the subject, wherein the flow generator comprises: a baseline valve assembly configured to control a flow rate of a baseline gas through the outlet; and a first valve assembly configured to control a flow rate of the first gas through the outlet; and a baseline valve assembly configured to control a flow rate of a baseline gas through the outlet; and a first valve assembly configured to control a flow rate of the first gas through the outlet; and one or more processors configured to execute processing modules, wherein the processing modules comprise: a baseline flow rate module configured to obtain a baseline flow rate for the baseline gas during generation of the simulated pressurized flow of gas, wherein the baseline flow rate is a function of a parameter of the partial pressure specified for the first gas from the gas flow data set; a first flow rate module configured to determine a first flow rate for the first gas based on the partial pressure specified for the first gas from the gas flow data set such that the first flow rate changes over time in accordance with the partial pressure specified for the first gas from the gas flow data set; and a control module configured to control the flow generator to generate the simulated pressurized flow of gas that simulates the respiratory gas flow of the subject represented by the gas flow data set, including controlling the baseline valve assembly to deliver the baseline gas to the outlet at the baseline flow rate and controlling the first valve assembly to deliver the first gas to the outlet at the first flow rate. a baseline flow rate module configured to obtain a baseline flow rate for the baseline gas during generation of the simulated pressurized flow of gas, wherein the baseline flow rate is a function of a parameter of the partial pressure specified for the first gas from the gas flow data set; a first flow rate module configured to determine a first flow rate for the first gas based on the partial pressure specified for the first gas from the gas flow data set such that the first flow rate changes over time in accordance with the partial pressure specified for the first gas from the gas flow data set; and a control module configured to control the flow generator to generate the simulated pressurized flow of gas that simulates the respiratory gas flow of the subject represented by the gas flow data set, including controlling the baseline valve assembly to deliver the baseline gas to the outlet at the baseline flow rate and controlling the first valve assembly to deliver the first gas to the outlet at the first flow rate.