mhurhangee/ep-ind-claims huggingface dataset:
A bifunctional agent that is suitable for suppressing the activation of T lymphocytes, said agent having the general structure wherein A is an antibody, antibody fragment or antibody mimetic directed against CD3, A' is an antibody, antibody fragment, or antibody mimetic directed against CD28, B is an antibody, antibody fragment, or antibody mimetic directed against latency-associated peptide of the TGFβ-LAP Small Latent Complex, wherein said antibody, antibody fragment or antibody mimetic is loaded with exogenous TGFβ-LAP complexes, and X is selected from the group consisting of a bead, a magnetic bead, a polymeric matrix, and a solid support, wherein said agent comprises more than one individual molecule of the types A, B, and A', wherein said antibodies, antibody fragments or antibody mimetics and the TGFβ-LAP complexes are present in a ratio of 0.5 to 1.5 parts A, 2.5 to 7.5 parts A', 2.5 to 7.5 parts B, and 0.02 to 10 parts TGFβ-LAP complexes, and wherein said antibody mimetics are selected from the group consisting of single-chain variable fragments (scFv), single-domain antibodies, affibodies, anticalins, DARPins, monobodies, and peptide aptamers. A is an antibody, antibody fragment or antibody mimetic directed against CD3, A' is an antibody, antibody fragment, or antibody mimetic directed against CD28, B is an antibody, antibody fragment, or antibody mimetic directed against latency-associated peptide of the TGFβ-LAP Small Latent Complex, wherein said antibody, antibody fragment or antibody mimetic is loaded with exogenous TGFβ-LAP complexes, and X is selected from the group consisting of a bead, a magnetic bead, a polymeric matrix, and a solid support,
An audio encoder for providing an encoded audio information on the basis of an input audio information, the audio encoder comprising: a bandwidth extension information provider configured to provide bandwidth extension information using a variable temporal resolution; a detector configured to detect an offset of a fricative or affricate; characterized in that the audio encoder is configured to adjust a temporal resolution used by the bandwidth extension information provider such that bandwidth extension information is provided with an increased temporal resolution in response to a detection of an offset of a fricative or affricate. a bandwidth extension information provider configured to provide bandwidth extension information using a variable temporal resolution; a detector configured to detect an offset of a fricative or affricate; characterized in that the audio encoder is configured to adjust a temporal resolution used by the bandwidth extension information provider such that bandwidth extension information is provided with an increased temporal resolution in response to a detection of an offset of a fricative or affricate.
An air conditioner having a compressor, an oil separator, a four-way valve, an outdoor heat exchanger, an indoor heat exchanger, and an accumulator, and the air conditioner is configured to cool or heat a room by circulating a refrigerant, the air conditioner comprising: a first block which is disposed on a first channel of the refrigerant between the oil separator and the four-way valve, the first block being modular and having a plurality of first control parts; and a second block which is disposed on a second channel of the refrigerant between the outdoor heat exchanger and the indoor heat exchanger, the second block being modular and having a plurality of second control parts, wherein the first block comprises a first housing having a part of the plurality of first control parts fixed outside the first housing, and other parts of the plurality of first control parts disposed inside the first housing. a first block which is disposed on a first channel of the refrigerant between the oil separator and the four-way valve, the first block being modular and having a plurality of first control parts; and a second block which is disposed on a second channel of the refrigerant between the outdoor heat exchanger and the indoor heat exchanger, the second block being modular and having a plurality of second control parts, wherein the first block comprises a first housing having a part of the plurality of first control parts fixed outside the first housing, and other parts of the plurality of first control parts disposed inside the first housing.
A data traffic management method, wherein the method comprises the following steps: obtaining traffic control information of a WiFi hotspot of a terminal, wherein the traffic control information comprises an upper traffic threshold; enabling the WiFi hotspot for sharing data traffic of the terminal with other terminals, wherein the data traffic comprises mobile network data traffic; obtaining a total data traffic value used by the other terminals that perform data connection by using the WiFi hotspot in a time period from enabling of the WiFi hotspot to a current time; disabling the WiFi hotspot when the total data traffic value is greater than or equal to the upper traffic threshold, characterized in that another application except the WiFi hotspot is still able to obtain data traffic after disabling the WiFi hotspot, wherein the data traffic is mobile data traffic, and is data traffic generated by the terminal by assessing a core network by using a base station. obtaining traffic control information of a WiFi hotspot of a terminal, wherein the traffic control information comprises an upper traffic threshold; enabling the WiFi hotspot for sharing data traffic of the terminal with other terminals, wherein the data traffic comprises mobile network data traffic; obtaining a total data traffic value used by the other terminals that perform data connection by using the WiFi hotspot in a time period from enabling of the WiFi hotspot to a current time; disabling the WiFi hotspot when the total data traffic value is greater than or equal to the upper traffic threshold, characterized in that another application except the WiFi hotspot is still able to obtain data traffic after disabling the WiFi hotspot, wherein the data traffic is mobile data traffic, and is data traffic generated by the terminal by assessing a core network by using a base station.
A system for ophthalmic surgery comprising: a pneumatic surgical instrument; and a flexible pneumatic drive line (402, 702, 802, 902) configured to couple the pneumatic surgical instrument to a surgical console configured to provide compressed gas to the pneumatic surgical instrument, the flexible pneumatic drive line having an internal bore (502, 602, 710, 810, 910) configured to deliver the compressed gas to the pneumatic surgical instrument, the internal bore having a non-uniform cross-section along a length of the flexible pneumatic drive line; wherein the flexible pneumatic drive line comprises a first segment and a second segment, the first segment defining a first passageway having a first internal diameter (ID1, IDS1) and the second segment defining a second passageway having a second internal diameter (ID2, IDS2), the first internal diameter being different than the second internal diameter and wherein the internal diameter of the internal bore decreases in diameter from the end coupled to the surgical console to the end coupled to the pneumatic surgical instrument. a pneumatic surgical instrument; and a flexible pneumatic drive line (402, 702, 802, 902) configured to couple the pneumatic surgical instrument to a surgical console configured to provide compressed gas to the pneumatic surgical instrument, the flexible pneumatic drive line having an internal bore (502, 602, 710, 810, 910) configured to deliver the compressed gas to the pneumatic surgical instrument, the internal bore having a non-uniform cross-section along a length of the flexible pneumatic drive line; wherein the flexible pneumatic drive line comprises a first segment and a second segment, the first segment defining a first passageway having a first internal diameter (ID1, IDS1) and the second segment defining a second passageway having a second internal diameter (ID2, IDS2), the first internal diameter being different than the second internal diameter and wherein the internal diameter of the internal bore decreases in diameter from the end coupled to the surgical console to the end coupled to the pneumatic surgical instrument.
An unmanned flying device comprising: a body; a first motor; a top rotor assembly driven by the first motor; at least first and second blades coupled to the top rotor assembly; a second motor; at least a bottom rotor assembly driven by the second motor; at least third and fourth blades coupled to the bottom rotor assembly; a central shaft; wherein the top and bottom rotor assemblies are mounted on, and spin about the central shaft, the top rotor assembly being positioned above the bottom rotor assembly along the central shaft; wherein the at least third and fourth blades are attached to a rotor bracket that is connected to the bottom rotor assembly through a radial bearing; a swashplate connected via linkages to the rotor bracket to make the pitch of said at least third and fourth blades change in response to an induced angle of the swashplate as it rotates around the central shaft; and a plurality of servo motors for changing the angle of the swashplate; wherein the first and second motors are positioned between the top rotor assembly and the bottom rotor assembly, the bottom rotor assembly is positioned above the swashplate, and the swashplate is positioned above the plurality of servo motors; wherein the controlled flight of the device is achievable by only changing the pitch of the rotor bracket to which the at least third and fourth blades are attached, no pitch control of the at least first and second blades being provided. a body; a first motor; a top rotor assembly driven by the first motor; at least first and second blades coupled to the top rotor assembly; a second motor; at least a bottom rotor assembly driven by the second motor; at least third and fourth blades coupled to the bottom rotor assembly; a central shaft; wherein the top and bottom rotor assemblies are mounted on, and spin about the central shaft, the top rotor assembly being positioned above the bottom rotor assembly along the central shaft; wherein the at least third and fourth blades are attached to a rotor bracket that is connected to the bottom rotor assembly through a radial bearing; a swashplate connected via linkages to the rotor bracket to make the pitch of said at least third and fourth blades change in response to an induced angle of the swashplate as it rotates around the central shaft; and a plurality of servo motors for changing the angle of the swashplate; wherein the first and second motors are positioned between the top rotor assembly and the bottom rotor assembly, the bottom rotor assembly is positioned above the swashplate, and the swashplate is positioned above the plurality of servo motors; wherein the controlled flight of the device is achievable by only changing the pitch of the rotor bracket to which the at least third and fourth blades are attached, no pitch control of the at least first and second blades being provided.
An apparatus for positioning an object, the apparatus comprising: at least one adjustment block, wherein each adjustment block comprises a support structure configured to mount an object, a base structure, and a plurality of hinged members arranged between the base structure and the support structure, wherein each hinged member includes at least one compliant joint and is configured to pivot relative to the support structure; an actuator system configured to actuate the adjustment block to move the object to a predetermined position; and a locking system configured to maintain a position of the adjustment block. at least one adjustment block, wherein each adjustment block comprises a support structure configured to mount an object, a base structure, and a plurality of hinged members arranged between the base structure and the support structure, wherein each hinged member includes at least one compliant joint and is configured to pivot relative to the support structure; a support structure configured to mount an object, a base structure, and a plurality of hinged members arranged between the base structure and the support structure, wherein each hinged member includes at least one compliant joint and is configured to pivot relative to the support structure; an actuator system configured to actuate the adjustment block to move the object to a predetermined position; and a locking system configured to maintain a position of the adjustment block.
A semiconductor laser comprising: a chip used as a gain medium of the semiconductor laser; and a platform, wherein: the chip is made of a semiconductor material; the semiconductor material has a direct bandgap; the chip comprises a first edge defining an outer portion of a side of the chip; the chip comprises a second edge defining an outer portion of another side of the chip; and the first edge is opposite the second edge, and wherein: the platform comprises silicon; the platform comprises a waveguide; and the chip is bonded to the platform, wherein the semiconductor laser is characterized by a wall in the chip, wherein the wall is between the first edge and the second edge; a coating disposed on the wall, wherein the coating forms a mirror in the chip; and a ridge formed in the chip, wherein: the ridge is configured to guide light in the chip; the ridge comprises a first end and a second end; the first end is opposite the second end; the first end terminates at the mirror; and the second end is optically coupled with the waveguide. a chip used as a gain medium of the semiconductor laser; and a platform, wherein: the chip is made of a semiconductor material; the semiconductor material has a direct bandgap; the chip comprises a first edge defining an outer portion of a side of the chip; the chip comprises a second edge defining an outer portion of another side of the chip; and the first edge is opposite the second edge, and the chip is made of a semiconductor material; the semiconductor material has a direct bandgap; the chip comprises a first edge defining an outer portion of a side of the chip; the chip comprises a second edge defining an outer portion of another side of the chip; and the first edge is opposite the second edge, and wherein: the platform comprises silicon; the platform comprises a waveguide; and the chip is bonded to the platform, the platform comprises silicon; the platform comprises a waveguide; and the chip is bonded to the platform, wherein the semiconductor laser is characterized by a wall in the chip, wherein the wall is between the first edge and the second edge; a coating disposed on the wall, wherein the coating forms a mirror in the chip; and a ridge formed in the chip, wherein: the ridge is configured to guide light in the chip; the ridge comprises a first end and a second end; the first end is opposite the second end; the first end terminates at the mirror; and the second end is optically coupled with the waveguide. the ridge is configured to guide light in the chip; the ridge comprises a first end and a second end; the first end is opposite the second end; the first end terminates at the mirror; and the second end is optically coupled with the waveguide.
Transmission unit for a communication system, comprising a computer unit and a communication controller by means of which the transmission unit is connected to a communication medium for the purpose of data transmission, wherein the transmission unit has means for signing, by means of a first signature, data that are to be transmitted by the communication controller via the communication medium, characterized in that the transmission unit has a separate hardware unit that is designed to form a further signature, as far as possible independently of the computer unit, by means of at least some of the data that need to be transmitted from the computer unit to the communication controller for the purpose of subsequent transmission via the communication medium.
Pharmaceutical composition made of at least one preparation, wherein the preparation comprises: tolerogenic liposomes tailored for effective phagocytosis and loaded with at least one maturation inhibitor of dendritic cells (DCs) selected from a) calcipotriol, b) glucocorticoids, and c) antisense oligonucleotides capable of gene silencing of different pro-inflammatory molecules including CD40, CD80, and CD86 and at least one antigen or allergen or peptide derived thereof selected from ovalbumin, methylated BSA (mBSA), or the myelin oligodendrocyte glycoprotein -derived peptide 35-55 (MOG, at least one immune modulator of phagocytosis selected from the nucleotides ATP and UTP, wherein at least said liposomes are embedded in a matrix suitable for locally restricted sustained release of therapeutically effective doses of said liposomes selected from PLGA-PEG-PLGA triblock copolymers. tolerogenic liposomes tailored for effective phagocytosis and loaded with at least one maturation inhibitor of dendritic cells (DCs) selected from a) calcipotriol, b) glucocorticoids, and c) antisense oligonucleotides capable of gene silencing of different pro-inflammatory molecules including CD40, CD80, and CD86 and at least one antigen or allergen or peptide derived thereof selected from ovalbumin, methylated BSA (mBSA), or the myelin oligodendrocyte glycoprotein -derived peptide 35-55 (MOG, at least one immune modulator of phagocytosis selected from the nucleotides ATP and UTP, wherein at least said liposomes are embedded in a matrix suitable for locally restricted sustained release of therapeutically effective doses of said liposomes selected from PLGA-PEG-PLGA triblock copolymers.
A listening device (62, 63), comprising: a speaker (64, 65); a microphone (66, 67) for detecting ambient noise; and a plug, for connection to a socket of an apparatus, characterised in that the listening device is configured to transfer through said plug a digital coding word, and wherein the digital coding word identifies characteristics of the listening device that require a particular noise reduction transfer function to be provided by noise reduction circuitry in the apparatus for the identified listening device. a speaker (64, 65); a microphone (66, 67) for detecting ambient noise; and a plug, for connection to a socket of an apparatus, characterised in that the listening device is configured to transfer through said plug a digital coding word, and wherein the digital coding word identifies characteristics of the listening device that require a particular noise reduction transfer function to be provided by noise reduction circuitry in the apparatus for the identified listening device.
An articulated box, in particular for a false ceiling, comprising: - an enclosure comprising a frame, referred to as the external frame, formed by four sides, defining a quadrilateral, on which a bottom intended to be fixed to a wall is mounted, - an internal frame formed by four profiled members, to the base of which a tensioned fabric is fixed, - at least one articulation connecting said internal frame and said enclosure so as to allow a tilting of said internal frame with respect to said enclosure, and - at least one closure for holding the internal frame in the so-called operating closed position, said internal frame being mounted so as to slide on the articulation, characterised in that the articulation is of the damping type for immobilising the internal frame in any tilted position and comprises a hinge assembly comprising a plate, a flange, a deformable mechanism of the deformable quadrilateral type composed of two articulated links and a damping means, said links (133, 134) and said damping means are articulated on the plate at one of their ends and on the flange at the other end. - an enclosure comprising a frame, referred to as the external frame, formed by four sides, defining a quadrilateral, on which a bottom intended to be fixed to a wall is mounted, - an internal frame formed by four profiled members, to the base of which a tensioned fabric is fixed, - at least one articulation connecting said internal frame and said enclosure so as to allow a tilting of said internal frame with respect to said enclosure, and - at least one closure for holding the internal frame in the so-called operating closed position,
A device for mooring boats comprising a connector (A; B) and further comprising two first hands connected to a bridge and on one side being connected horizontally to two legs on first lower shafts, and two second hands connected to the legs on first upper shafts, wherein each of the first hands on the other side are vertically connected to a respective one of the second hands by a head via second lower shafts and second upper shafts, the second lower shafts and second upper shafts having the same distance in between as the first lower shafts and first upper shafts; wherein the heads have on upper and lower sides square profiles for mounting the connectors (A; B), screws for fixing, a float at a frontal side of the head with a telescopic holder, which passes through its housing, fixed on the head with screws, wherein the device further comprises two springs connected to the legs and the first hands and two shock absorbers connected to the legs and the second hands. two first hands connected to a bridge and on one side being connected horizontally to two legs on first lower shafts, and two second hands connected to the legs on first upper shafts, wherein each of the first hands on the other side are vertically connected to a respective one of the second hands by a head via second lower shafts and second upper shafts, the second lower shafts and second upper shafts having the same distance in between as the first lower shafts and first upper shafts; wherein the heads have on upper and lower sides square profiles for mounting the connectors (A; B), screws for fixing, a float at a frontal side of the head with a telescopic holder, which passes through its housing, fixed on the head with screws, wherein the device further comprises two springs connected to the legs and the first hands and two shock absorbers connected to the legs and the second hands. on upper and lower sides square profiles for mounting the connectors (A; B), screws for fixing, a float at a frontal side of the head with a telescopic holder, which passes through its housing, fixed on the head with screws, wherein the device further comprises two springs connected to the legs and the first hands and two shock absorbers connected to the legs and the second hands.