mhurhangee/ep-ind-claims huggingface dataset:
A method for preparing a pharmaceutical composition of a substance useful as a drug for the amelioration or treatment of a disease, said method comprising: (a) contacting a test sample comprising an in vitro differentiated cell with a test substance to be screened, wherein said cell is induced to display a predefined diseased phenotype which substantially corresponds to a phenotype of a cell of a diseased cell, tissue or organ; and (b) determining a responsive change of the phenotype in said test sample, wherein a responsive change (i) preventing or delaying the onset or the progression of the diseased phenotype is indicative for a useful drug; and (ii) enhancing the onset or progression the diseased phenotype is indicative for the toxicity of the substance; and (c) mixing the substance useful as a drug with a pharmaceutically acceptable diluent or carrier. (a) contacting a test sample comprising an in vitro differentiated cell with a test substance to be screened, wherein said cell is induced to display a predefined diseased phenotype which substantially corresponds to a phenotype of a cell of a diseased cell, tissue or organ; and (b) determining a responsive change of the phenotype in said test sample, wherein a responsive change (i) preventing or delaying the onset or the progression of the diseased phenotype is indicative for a useful drug; and (ii) enhancing the onset or progression the diseased phenotype is indicative for the toxicity of the substance; and (i) preventing or delaying the onset or the progression of the diseased phenotype is indicative for a useful drug; and (ii) enhancing the onset or progression the diseased phenotype is indicative for the toxicity of the substance; and (c) mixing the substance useful as a drug with a pharmaceutically acceptable diluent or carrier.
A gas-phase process for the preparation of butadiene comprising (i) providing a gas stream G-1 comprising ethanol; (ii) contacting the gas stream G-1 comprising ethanol with a catalyst, thereby obtaining a gas stream G-2 comprising butadiene, wherein the catalyst comprises a zeolitic material having an MWW framework structure comprising YO 2, wherein Y is Si, wherein at least a portion of Y comprised in the framework structure is isomorphously substituted by one or more elements X, wherein X is selected from the group consisting of Ti, Sn, and a combination thereof. (i) providing a gas stream G-1 comprising ethanol; (ii) contacting the gas stream G-1 comprising ethanol with a catalyst, thereby obtaining a gas stream G-2 comprising butadiene,
A nestable container, in particular a transport container, having a substantially rectangular bottom and a wall extending from the bottom, the wall forming a container opening opposite the bottom, expanding continuously or gradually at least in sections towards the container opening and having reinforced wall portions arranged on its long side walls, the wall thickness of which is at least in sections greater than the wall thickness of the remaining wall portions, characterized in that the reinforced wall portions are movably coupled to the bottom and/or the remaining wall portions such that they are movable or tiltable from a normal position into a flatter position for nesting identical or compatible containers, in which the reinforced wall portions are inclined more flatly than the remaining wall portions relative to the bottom.
Distance compensation element for arrangement between two components - with a metal foil and - with spring elements integral with the metal foil, - wherein the spring elements protrude from the plane of the metal foil, - wherein the spring elements are designed to be in contact with at least one of the components, and. - wherein a slit arrangement with a plurality of slits is introduced into the metal foil, - wherein the metal foil is deformed by stretching. characterized in, - that the metal foil consists of at least two metal layers, - that at least one metal layer consists of a first metal, - that at least one metal layer consists of a second metal, - in that the first metal has a greater modulus of elasticity than the second metal, and - that the second metal has a greater thermal conductivity than the first metal. - with a metal foil and - with spring elements integral with the metal foil, - wherein the spring elements protrude from the plane of the metal foil, - wherein the spring elements are designed to be in contact with at least one of the components, and. - wherein a slit arrangement with a plurality of slits is introduced into the metal foil, - wherein the metal foil is deformed by stretching. - that the metal foil consists of at least two metal layers, - that at least one metal layer consists of a first metal, - that at least one metal layer consists of a second metal, - in that the first metal has a greater modulus of elasticity than the second metal, and - that the second metal has a greater thermal conductivity than the first metal.
A vanadium-containing compound or composition for use in a therapeutic method for enhancing infection, growth, spread, or titer of an oncolytic RNA virus in a cancer or tumor cell, said method comprising administering said vanadium-containing compound or composition to the cancer or tumor cell before, after, or concurrently with infection of the cancer or tumor cell with the oncolytic RNA virus.
A method for performing quality control on a diagnostic analyzer, comprising: receiving a quality control measurement value from each of a plurality of diagnostic analyzers; receiving, from a target diagnostic analyzer, a quality control measurement value; comparing the quality control measurement value received from the target diagnostic analyzer with first statistical criteria based on the plurality of quality control measurement values received from the plurality of diagnostic analyzers; and communicating a comparison result to a user interface associated with the target diagnostic analyzer; wherein the first statistical criteria define a range having an upper limit and a lower limit associated with the plurality of quality control measurement values; characterized in that when the quality control measurement value received from the target diagnostic analyzer is outside of the range, the method further comprises: determining a type of abnormality associated with the quality control measurement value received from the target diagnostic analyzer; selecting a troubleshooting instruction based on the type of abnormality; and communicating the troubleshooting instruction to the user interface. receiving a quality control measurement value from each of a plurality of diagnostic analyzers; receiving, from a target diagnostic analyzer, a quality control measurement value; comparing the quality control measurement value received from the target diagnostic analyzer with first statistical criteria based on the plurality of quality control measurement values received from the plurality of diagnostic analyzers; and communicating a comparison result to a user interface associated with the target diagnostic analyzer; wherein the first statistical criteria define a range having an upper limit and a lower limit associated with the plurality of quality control measurement values; characterized in that when the quality control measurement value received from the target diagnostic analyzer is outside of the range, the method further comprises: determining a type of abnormality associated with the quality control measurement value received from the target diagnostic analyzer; selecting a troubleshooting instruction based on the type of abnormality; and communicating the troubleshooting instruction to the user interface. determining a type of abnormality associated with the quality control measurement value received from the target diagnostic analyzer; selecting a troubleshooting instruction based on the type of abnormality; and communicating the troubleshooting instruction to the user interface.
A mounting system for supporting a radiant heating device above a bottom panel of a cooking hob, comprising at least one supporting bracket and dedicated receptacle means (26, 28) in the bottom panel, wherein: - the supporting bracket is formed as a leaf-spring with a mountable portion and a free end portion, - the supporting bracket comprises at least one bending (18, 20) between the mountable portion and the free end portion, characterized in that - the receptacle means (26, 28) include at least two parallel guiding elements, which are cut in the bottom panel and bent up, so that the mountable portion is slidable along the longitudinal axis of said guiding elements, - the mountable portion comprises at least one stop unit, so that the mountable portion can be inserted between the guiding elements only until to a predetermined position, - the receptacle means (26, 28) include at least one barbed hook cut in the bottom panel and bent up, and - the bending between the mountable portion and the free end portion is provided for snapping-in at the barbed hook in order to prevent the motion of the supporting bracket in the direction of the free end portion. - the supporting bracket is formed as a leaf-spring with a mountable portion and a free end portion, - the supporting bracket comprises at least one bending (18, 20) between the mountable portion and the free end portion, - the receptacle means (26, 28) include at least two parallel guiding elements, which are cut in the bottom panel and bent up, so that the mountable portion is slidable along the longitudinal axis of said guiding elements, - the mountable portion comprises at least one stop unit, so that the mountable portion can be inserted between the guiding elements only until to a predetermined position, - the receptacle means (26, 28) include at least one barbed hook cut in the bottom panel and bent up, and - the bending between the mountable portion and the free end portion is provided for snapping-in at the barbed hook in order to prevent the motion of the supporting bracket in the direction of the free end portion.
An ultrasonic diagnostic apparatus including a probe (14; 142; 230; 420), characterized by comprising: a fastening part (20; 21; 240) having a band shape and wound around a diagnosis object; and a mover (30; 32; 430) moving the probe (14; 142; 230; 420) along a circumference of the diagnosis object 810); and a button operates the mover (30; 32; 430), wherein the mover (30;32;430) comprises: a gear rack disposed on the fastening part (20;21;240) in a longitudinal direction in which the probe is moved; and a movable examination part, moving along the gear rack and having the probe secured to a side surface thereof, including: a pinion member engaging with the gear rack; a transport motor driving the pinion member; a movable plate on which the transport motor, pinion member and the probe are mounted; and anti-separation rings each bent at opposite sides of the movable plate to catch lateral sides of the fastening part (20;21;240). a fastening part (20; 21; 240) having a band shape and wound around a diagnosis object; and a mover (30; 32; 430) moving the probe (14; 142; 230; 420) along a circumference of the diagnosis object 810); and a button operates the mover (30; 32; 430), wherein the mover (30;32;430) comprises: a gear rack disposed on the fastening part (20;21;240) in a longitudinal direction in which the probe is moved; and a movable examination part, moving along the gear rack and having the probe secured to a side surface thereof, including: a pinion member engaging with the gear rack; a transport motor driving the pinion member; a movable plate on which the transport motor, pinion member and the probe are mounted; and anti-separation rings each bent at opposite sides of the movable plate to catch lateral sides of the fastening part (20;21;240). a gear rack disposed on the fastening part (20;21;240) in a longitudinal direction in which the probe is moved; and a movable examination part, moving along the gear rack and having the probe secured to a side surface thereof, including: a pinion member engaging with the gear rack; a transport motor driving the pinion member; a movable plate on which the transport motor, pinion member and the probe are mounted; and anti-separation rings each bent at opposite sides of the movable plate to catch lateral sides of the fastening part (20;21;240). a pinion member engaging with the gear rack; a transport motor driving the pinion member; a movable plate on which the transport motor, pinion member and the probe are mounted; and anti-separation rings each bent at opposite sides of the movable plate to catch lateral sides of the fastening part (20;21;240).
An end stop for a slide fastener comprising a linear fastener element row of synthetic resin mounted on a side edge of a fastener tape, and with a rod-like body of synthetic resin inserted into a coupling space portion located in an inside of coupling heads in plural fastener elements located at an end of the fastener element row so as to form the end stop for a slider, characterized in that a fused portion is provided by fastener elements of several pitches fused together with the rod-like body, and a non-fused portion is provided without fused fastener elements of several pitches of the plural fastener elements in which the rod-like body is inserted, the end stop being formed by the fused portion and the non-fused portion.
A specimen analyzing apparatus for measuring a specimen by using a reagent, comprising: a dispensing mechanism (21, 22, 23, 24, 25) which includes a dispensing tube for suctioning and discharging liquid; a reagent container holder (13, 14) from which a reagent container is removable when the reagent container being in a container removal area; a main body cover for covering at least the dispensing mechanism and the reagent container holder; a cleaning section (38a, 38b, 38c, 38d, 38e) for cleaning the dispensing tube therein, which is disposed away from the replacement route and is provided with an opening section opened upward from which the dispensing tube is contained a receiving section for receiving a replacement command for a replacement of the reagent; and a controller for controlling the dispensing mechanism so as to retreat the dispensing tube from the container removal area to a retreated position which does not interfere with replacing the reagent container by an operator when the replacement command has been received by the receiving section, wherein the retreated position is a position where the dispensing tube does not interfere with a replacement route, from an open-side space at the time of opening the main body cover to a space above the container removal area, for replacing the reagent container by the operator, and wherein the retreated position of the dispensing tube is positioned above the opening section of the cleaning section. a dispensing mechanism (21, 22, 23, 24, 25) which includes a dispensing tube for suctioning and discharging liquid; a reagent container holder (13, 14) from which a reagent container is removable when the reagent container being in a container removal area; a main body cover for covering at least the dispensing mechanism and the reagent container holder; a cleaning section (38a, 38b, 38c, 38d, 38e) for cleaning the dispensing tube therein, which is disposed away from the replacement route and is provided with an opening section opened upward from which the dispensing tube is contained a receiving section for receiving a replacement command for a replacement of the reagent; and a controller for controlling the dispensing mechanism so as to retreat the dispensing tube from the container removal area to a retreated position which does not interfere with replacing the reagent container by an operator when the replacement command has been received by the receiving section, wherein the retreated position is a position where the dispensing tube does not interfere with a replacement route, from an open-side space at the time of opening the main body cover to a space above the container removal area, for replacing the reagent container by the operator, and wherein the retreated position of the dispensing tube is positioned above the opening section of the cleaning section.
A thermoplastic molding material comprising A) 10 to 98 wt% of a thermoplastic polyurethane, B) 1 to 50 wt% of a thermoplastic pyrrolidone-containing polyamide comprising units derived from 2-pyrrolidone, C) 0 to 40 wt% of a halogen-free flame retardant, D) 0 to 60 wt% of a fibrous or particulate filler or mixtures thereof, E) 0 to 30 wt% of further additives, wherein the weight percentages A) to E) sum to 100%. A) 10 to 98 wt% of a thermoplastic polyurethane, B) 1 to 50 wt% of a thermoplastic pyrrolidone-containing polyamide comprising units derived from 2-pyrrolidone, C) 0 to 40 wt% of a halogen-free flame retardant, D) 0 to 60 wt% of a fibrous or particulate filler or mixtures thereof, E) 0 to 30 wt% of further additives,
A compound of the formula: wherein A is selected from the group consisting of; R 1 is H or F; R 2 is H, -CH 2 OH, C1-C3 alkyl, R 3 is H, F, or CN; R 4 is H, F; or CN; and R 5 is H, -CH 3, or -OCH 3; or a pharmaceutically acceptable salt thereof. R 1 is H or F; R 2 is H, -CH 2 OH, C1-C3 alkyl, R 3 is H, F, or CN; R 4 is H, F; or CN; and R 5 is H, -CH 3, or -OCH 3;
A method of determining a twist angle of a wind turbine blade, the method comprising: a. providing first and second transmitters on the wind turbine blade (24a, 24b, 24c), the first transmitter being spaced apart from a receiver by a first distance, and the second transmitter being spaced apart from the receiver by a second distance, the transmitters being arranged such that twisting of the blade causes an increase in one of the first or second distances and a decrease in the other of the first or second distances; b. transmitting a blinking signal from each of the first and second transmitters towards the receiver, the blinking signals having a blinking frequency; the method being characterised by the following steps: c. varying the blinking frequency of the blinking signals; d. monitoring the amplitude of the blinking signal received by the receiver as the blinking frequency is varied; e. determining a particular blinking frequency that results in an increased amplitude of the blinking signal received by the receiver; and f. using the determined particular blinking frequency to calculate the blade twist angle. a. providing first and second transmitters on the wind turbine blade (24a, 24b, 24c), the first transmitter being spaced apart from a receiver by a first distance, and the second transmitter being spaced apart from the receiver by a second distance, the transmitters being arranged such that twisting of the blade causes an increase in one of the first or second distances and a decrease in the other of the first or second distances; b. transmitting a blinking signal from each of the first and second transmitters towards the receiver, the blinking signals having a blinking frequency; the method being characterised by the following steps: c. varying the blinking frequency of the blinking signals; d. monitoring the amplitude of the blinking signal received by the receiver as the blinking frequency is varied; e. determining a particular blinking frequency that results in an increased amplitude of the blinking signal received by the receiver; and f. using the determined particular blinking frequency to calculate the blade twist angle.
Flexographic printing unit having an anilox roller, a forme cylinder and an impression cylinder and allowing the use of forme cylinders of different diameters, wherein the axes of rotation of the screen roller and forme cylinder are disposed in a horizontal plane independently of the diameter of the forme cylinder and the axes of rotation of the forme cylinder and the impression cylinder are disposed in a vertical plane, characterized in that the flexographic printing unit includes at least one toggle lever system (4.1) for applying a pre-load to the forme cylinder.
A food pressure-cooking appliance comprising: - a bowl and a lid adapted to tightly close the bowl to form a cooking chamber, - a member for controlling the locking / unlocking of the lid on the bowl, intended to be manually operated by a user, said member being movable along a stroke extending between at least one unlocking position and one locking position, and being kinematically linked to a locking mechanism mounted movable on the lid to displace said locking mechanism and to ensure the locking / unlocking of the lid, - retractable holding means adapted to exert a holding effort on the control member when the latter is in its unlocking position, said appliance being characterized in that - the holding means are adapted to exert a return force on the control member when the latter is in the locking position, so as to hold said locking position. - a bowl and a lid adapted to tightly close the bowl to form a cooking chamber, - a member for controlling the locking / unlocking of the lid on the bowl, intended to be manually operated by a user, said member being movable along a stroke extending between at least one unlocking position and one locking position, and being kinematically linked to a locking mechanism mounted movable on the lid to displace said locking mechanism and to ensure the locking / unlocking of the lid, - retractable holding means adapted to exert a holding effort on the control member when the latter is in its unlocking position, said appliance being characterized in that - the holding means are adapted to exert a return force on the control member when the latter is in the locking position, so as to hold said locking position.
Closure device, in particular for a caravan or mobile home, wherein the closure device has a swivel catch and a locking member which can be fastened to a first fixed and a second furniture part (70, 80) movable relative to the first furniture part, respectively, wherein the swivel catch is pivotably connected to a holder by means of a pivot bearing, wherein the swivel catch is movable in an opening direction from a closed position into an unlocked position by means of a tension spring, wherein the swivel catch can be locked in the closed position on the locking member by means of a releasable positive locking connection and can be unlocked relative to the latter in the unlocked position, and wherein the positive locking connection can be unlocked by applying an overstroke movement in the closing direction, opposite to the opening direction, wherein the positive locking connection is formed by a control element (63.1, 63.2) and a heart curve guide, and wherein the control element (63.1, 63.2), in the closed position, bears positively against a blocking section (26.6) of the heart curve guide, characterized in that the heart curve guide or the heart curve guides is/are arranged in a cavity which is accessible via an insertion opening (26. 1) in order to displace the control element or elements (63.1, 63.2) in the heart curve guide or the heart curve guides, and in that the swivel catch has two shaped pieces (20.1, 20.2) which are connected to one another in the region of their connecting sides, and in that the cavity extends beyond the connecting sides into both shaped pieces (20.1, 20.2).
A Doherty power amplifier circuit, comprising a power divider circuit, and a power amplifier circuit connected with the power divider circuit; and the Doherty power amplifier circuit further comprising a combination output circuit connected with the power amplifier circuit, wherein the combination output circuit is a rheostat filter; wherein the rheostat filter is formed by four microstrip lines having different sizes, which are connected in series, and an electrical length of each of the four microstrip lines is 1/16 wave length, and characteristic impedances are separately 53 Ohms, 12 Ohms, 96 Ohms and 23 Ohms.