mhurhangee/ep-ind-claims huggingface dataset:
A nucleic acid comprising a nucleotide sequence encoding a voltage-dependent ion channel fusion subunit bound to a nucleotide sequence encoding at least one bioluminescent donor molecule and bound to a nucleotide sequence encoding at least one fluorescent acceptor molecule, wherein said bioluminescent donor molecule and fluorescent acceptor molecule are selected so that the emission spectrum of the bioluminescent donor molecule overlaps with the absorbance spectrum of the acceptor molecule, such that the light energy delivered by the bioluminescent donor molecule is at a wavelength that is able to excite the fluorescent acceptor molecule, wherein the bioluminescent donor molecule is bound to C-terminal of channel subunit and fluorescent acceptor molecule is bound to N-terminal of said channel subunit, or the bioluminescent donor molecule is bound to N-terminal of channel subunit and fluorescent acceptor molecule is bound to C-terminal of said channel subunit, and wherein said voltage-dependent ion channel subunit is a subunit of a voltage-dependent cation channel or voltage-dependent anion channel and comprises 2 to 24 transmembrane domains.
An air conditioning system comprising: an outdoor unit including a control device; an indoor unit; and an outside air processor, wherein the indoor unit is capable of performing ordinary operation control to adjust a temperature of air in a room, the air being taken in the indoor unit, and supply the air into the room, and output restriction control under which an output is restricted as compared with an output under the ordinary operation control, the outside air processor is capable of performing ordinary operation control to adjust at least one of a temperature and a humidity of air outside the room, the air being taken in the outside air processor, and supply the air into the room, and output restriction control under which an output is restricted as compared with an output under the ordinary operation control, characterized in that the indoor unit is communicably connected to the control device; the outside air processor is communicably connected to the control device; and the control device causes the outside air processor to shift from the ordinary operation control to the output restriction control on condition that the indoor unit shifts from the ordinary operation control to the output restriction control. an outdoor unit including a control device; an indoor unit; and an outside air processor, wherein the indoor unit is capable of performing ordinary operation control to adjust a temperature of air in a room, the air being taken in the indoor unit, and supply the air into the room, and output restriction control under which an output is restricted as compared with an output under the ordinary operation control, the outside air processor is capable of performing ordinary operation control to adjust at least one of a temperature and a humidity of air outside the room, the air being taken in the outside air processor, and supply the air into the room, and output restriction control under which an output is restricted as compared with an output under the ordinary operation control, characterized in that the indoor unit is communicably connected to the control device; the outside air processor is communicably connected to the control device; and the control device causes the outside air processor to shift from the ordinary operation control to the output restriction control on condition that the indoor unit shifts from the ordinary operation control to the output restriction control.
An electric connector comprising: a housing including an extension receiving cavity and a plurality of contact insert slots; a plurality of contacts configured to be at least partially inserted to the plurality of contact insert slots; and a wire holder including a wire support extension configured to be at least partially inserted to the extension receiving cavity, the wire support extension including a plurality of wire receiving passages configured to be aligned to the plurality of contact insert slots when the wire support extension is inserted to the extension receiving cavity, wherein the plurality of wire receiving passages are configured to arrange wires of a first cable thereon and align the wires of the first cable with the plurality of contact insert slots, the wires of the first cable having a first diameter, and wherein the wire holder includes a plurality of wire support ribs, the plurality of wire support ribs at least partially arranged on the plurality of wire receiving passages and configured to arrange wires of a second cable on the plurality of wire receiving passages and align the wires of the second cable with the plurality of contact insert slots, the wires of the second cable having a second diameter smaller than the first diameter. a housing including an extension receiving cavity and a plurality of contact insert slots; a plurality of contacts configured to be at least partially inserted to the plurality of contact insert slots; and a wire holder including a wire support extension configured to be at least partially inserted to the extension receiving cavity, the wire support extension including a plurality of wire receiving passages configured to be aligned to the plurality of contact insert slots when the wire support extension is inserted to the extension receiving cavity, wherein the plurality of wire receiving passages are configured to arrange wires of a first cable thereon and align the wires of the first cable with the plurality of contact insert slots, the wires of the first cable having a first diameter, and wherein the wire holder includes a plurality of wire support ribs, the plurality of wire support ribs at least partially arranged on the plurality of wire receiving passages and configured to arrange wires of a second cable on the plurality of wire receiving passages and align the wires of the second cable with the plurality of contact insert slots, the wires of the second cable having a second diameter smaller than the first diameter.
A piling apparatus for pile assembly, comprising at least one walled pipe, a clamping frame having a clamping mechanism to link to the walled pipe which has been inserted into the ground, a pressing stand linked to the clamping frame, pressing cylinders having one end linked to the base of the pressing stand, another end linked to a holding clamp, wherein the holding clamp is used for clamping the material, so as to force at least one material to travel throughout the interior of the walled pipe by using the friction between the walled pipe which has been inserted into the ground with the ground served as a counterpoise, wherein components of the apparatus are constructed to press a pressing force against the material, formed by pressing cylinders applied to the materials by means of the holding clamp, and a reactive force transferred via the pressing stand, the clamping mechanism, the clamping frame to the walled pipe and balanced by the friction between the walled pipe and the ground.
A probe set comprising: at least one probe comprising a first portion of the probe complementary to a primary nucleotide portion of a target nucleic acid, and a second portion of the probe complementary to a secondary nucleotide portion of the target nucleic acid, wherein the probe overlaps a breakpoint between the primary and the secondary nucleotide portion of the target nucleic acid, and wherein the length of second portion of the probe represents about 9% to about 42% of a total probe length, and at least one further probe complementary only to the primary nucleotide portion of the target nucleic acid, wherein the further probe does not overlap a breakpoint between the primary and the secondary nucleotide portion of the target nucleic acid. at least one probe comprising a first portion of the probe complementary to a primary nucleotide portion of a target nucleic acid, and a second portion of the probe complementary to a secondary nucleotide portion of the target nucleic acid, a first portion of the probe complementary to a primary nucleotide portion of a target nucleic acid, and a second portion of the probe complementary to a secondary nucleotide portion of the target nucleic acid, wherein the probe overlaps a breakpoint between the primary and the secondary nucleotide portion of the target nucleic acid, and wherein the length of second portion of the probe represents about 9% to about 42% of a total probe length, and at least one further probe complementary only to the primary nucleotide portion of the target nucleic acid, wherein the further probe does not overlap a breakpoint between the primary and the secondary nucleotide portion of the target nucleic acid.
A latch apparatus (1, 101, 301), comprising: a case which is mounted on a mount member and in which an entrance groove (21, 121, 321) which a striker enters is formed; and a latch (4, 104, 304), which is accommodated in the case so as to be rotationally movable, and which is configured to be brought into engagement with the striker which enters the entrance groove (21, 121, 321), characterized in that the latch apparatus (1, 101, 301) comprises a fastening member (7, 107, 307) configured to fasten the case to the mount member such that the case is moveable relative to the striker, the fastening member (7, 107, 307) being provided within a range defined by projecting an area on the case, the area having a radius centering at the striker being in engagement with the latch (4, 104, 304) and extending to an outermost position of the latch (4, 104, 304) being in engagement with the striker. a case which is mounted on a mount member and in which an entrance groove (21, 121, 321) which a striker enters is formed; and a latch (4, 104, 304), which is accommodated in the case so as to be rotationally movable, and which is configured to be brought into engagement with the striker which enters the entrance groove (21, 121, 321), characterized in that the latch apparatus (1, 101, 301) comprises a fastening member (7, 107, 307) configured to fasten the case to the mount member such that the case is moveable relative to the striker, the fastening member (7, 107, 307) being provided within a range defined by projecting an area on the case, the area having a radius centering at the striker being in engagement with the latch (4, 104, 304) and extending to an outermost position of the latch (4, 104, 304) being in engagement with the striker.
A method for potting an electrical module, comprising: placing the electrical module in a potting mold, wherein the potting mold comprises an interior topology comprising a plurality of level surfaces (106, 108, 110, 112), wherein two or more of the plurality of level surfaces are at different heights, wherein each one of the plurality of level surfaces (106, 108, 110, 112) corresponds to a topology of a corresponding component of a plurality of components of the electrical module; filling the potting mold with a potting compound; curing the potting compound over the electrical module, and removing the electrical module from the potting mold, wherein the potting compound when molded to the electrical module comprises a plurality of level surfaces corresponding to said plurality of level surfaces (106, 108, 110, 112) of the potting mold. placing the electrical module in a potting mold, wherein the potting mold comprises an interior topology comprising a plurality of level surfaces (106, 108, 110, 112), wherein two or more of the plurality of level surfaces are at different heights, wherein each one of the plurality of level surfaces (106, 108, 110, 112) corresponds to a topology of a corresponding component of a plurality of components of the electrical module; filling the potting mold with a potting compound; curing the potting compound over the electrical module, and
Damper mounting for supporting a suspension component on a motor vehicle body, comprising: - a first mounting element for fixing to a motor vehicle body; - a second mounting element for fixing to the suspension component; and - a damping element which is arranged between the first and second mounting elements (12, 14) viewed in the radial direction (r) and is made of an impact-absorbing material, characterised in that a coupling element is arranged between the first and second mounting elements (12, 14), via which the second mounting element is actively connected to at least one active spring element arranged on the coupling element and effective in series to the damping element. - a first mounting element for fixing to a motor vehicle body; - a second mounting element for fixing to the suspension component; and - a damping element which is arranged between the first and second mounting elements (12, 14) viewed in the radial direction (r) and is made of an impact-absorbing material, characterised in that a coupling element is arranged between the first and second mounting elements (12, 14), via which the second mounting element is actively connected to at least one active spring element arranged on the coupling element and effective in series to the damping element.
A turning method for a computerized numerical control lathe comprising the steps of: - providing a cutting tool comprising a coupling portion, an intermediate portion and a cutting portion, the intermediate portion extending between the coupling portion and the cutting portion, a longitudinal center axis of the coupling portion defining a tool rotational axis, the intermediate portion extending along a longitudinal center axis thereof, the cutting portion comprising a top surface, the top surface facing away from the coupling portion, the cutting portion comprising a first nose portion, the first nose portion comprising a first cutting edge, a second cutting edge, and a convex nose cutting edge connecting the first and second cutting edges (11, 12); - providing a metal work piece; - rotating the metal work piece around a work piece rotational axis; - setting the tool rotational axis perpendicular to or substantially perpendicular to the work piece rotational axis; - making a first pass such that the first cutting edge is active and such that the second cutting edge is inactive, - making a second pass such that the first cutting edge is inactive and such that the second cutting edge is active, where the second pass is in a longitudinally or radially opposite or substantially opposite direction to the first pass; and - rotating the turning tool around the tool rotational axis during the first pass and/or during the second pass and/or after the first pass but prior to the second pass. - providing a cutting tool comprising a coupling portion, an intermediate portion and a cutting portion, the intermediate portion extending between the coupling portion and the cutting portion, a longitudinal center axis of the coupling portion defining a tool rotational axis, the intermediate portion extending along a longitudinal center axis thereof, the cutting portion comprising a top surface, the top surface facing away from the coupling portion, the cutting portion comprising a first nose portion, the first nose portion comprising a first cutting edge, a second cutting edge, and a convex nose cutting edge connecting the first and second cutting edges (11, 12); - providing a metal work piece; - rotating the metal work piece around a work piece rotational axis; - setting the tool rotational axis perpendicular to or substantially perpendicular to the work piece rotational axis; - making a first pass such that the first cutting edge is active and such that the second cutting edge is inactive, - making a second pass such that the first cutting edge is inactive and such that the second cutting edge is active, where the second pass is in a longitudinally or radially opposite or substantially opposite direction to the first pass; and - rotating the turning tool around the tool rotational axis during the first pass and/or during the second pass and/or after the first pass but prior to the second pass.
A method for processing, by means of a wearable health monitoring device, PPG signals including red and infrared, IR, average frame signals comprising: selecting a possible gain value between red and infrared, IR, frame signals, multiplying the red average frame signal by the possible gain value, and determining the residual error with respect to the infrared, IR, average frame signal, whereby the possible gain value is found by: averaging the two frames together first to provide an average frame signal with reduced noise; performing linear regression of the red versus combined and IR versus combined and then finding the ratio of these two results. selecting a possible gain value between red and infrared, IR, frame signals, multiplying the red average frame signal by the possible gain value, and determining the residual error with respect to the infrared, IR, average frame signal, averaging the two frames together first to provide an average frame signal with reduced noise; performing linear regression of the red versus combined and IR versus combined and then finding the ratio of these two results.
A cell expressing a CAR molecule that binds CD19 (a CAR19-expressing cell) for use in the treatment of a disease associated with expression of CD19 in a subject, wherein the subject is a complete responder, a partial responder, has stable disease, or has progressive disease, after treatment with a BTK inhibitor, and wherein the treatment with said CAR19-expressing cell comprises administering the CAR19-expressing cell during the period of said complete response, partial response, stable disease, or progressive disease.
A composition comprising a) at least 1% by weight of copolymer synthesized from monomers M comprising i) at least one ethylenically unsaturated monomer M1 containing sulfonic acid groups, ii) at least one monomer M2 selected from C 1 -C 4 alkyl (meth)acrylates, and iii) at least one monomer M3 selected from C 6 -C 22 alkyl (meth)acrylates; b) at least 10% by weight of organic solvent; c) not more than 10% by weight of water; d) at least 1 % by weight of water-insoluble pesticide in dissolved form, wherein the water-insoluble pesticide has a solubility in water of up to and including 10 g/l at 20 °C; and e) at least 1 % by weight of nonionic surfactant. a) at least 1% by weight of copolymer synthesized from monomers M comprising i) at least one ethylenically unsaturated monomer M1 containing sulfonic acid groups, ii) at least one monomer M2 selected from C 1 -C 4 alkyl (meth)acrylates, and iii) at least one monomer M3 selected from C 6 -C 22 alkyl (meth)acrylates; i) at least one ethylenically unsaturated monomer M1 containing sulfonic acid groups, ii) at least one monomer M2 selected from C 1 -C 4 alkyl (meth)acrylates, and iii) at least one monomer M3 selected from C 6 -C 22 alkyl (meth)acrylates; b) at least 10% by weight of organic solvent; c) not more than 10% by weight of water; d) at least 1 % by weight of water-insoluble pesticide in dissolved form, wherein the water-insoluble pesticide has a solubility in water of up to and including 10 g/l at 20 °C; and e) at least 1 % by weight of nonionic surfactant.
Bit for an animal, comprising: - at least one mouthpiece, - at least one C-shaped piece, arranged to cooperate with bridles, - a connecting piece, characterized in that said mouthpiece comprises two first apertures, said connecting piece comprises two second apertures, a first aperture defining with a second aperture a space arranged to receive one end of the C-shaped piece, and in that the bit comprises: - fixing means, arranged on the one hand to fix the C-shaped piece between said mouthpiece and said connecting part and on the other hand to fix said mouthpiece to said connecting part. - at least one mouthpiece, - at least one C-shaped piece, arranged to cooperate with bridles, - a connecting piece, - fixing means, arranged on the one hand to fix the C-shaped piece between said mouthpiece and said connecting part and on the other hand to fix said mouthpiece to said connecting part.
A packaged endoscopic fluid applicator comprising: an outer delivery device including a handle at a proximal end and an elongate tubular element extending outwardly from the handle to a distal end, wherein the outer delivery device has a channel extending therethrough between the proximal and distal ends; an inner plunger device including a handle element at a proximal end and an elongate plunger element extending outwardly from the handle to a distal end, wherein the elongate plunger element is sized and shaped so as to be slidably receivable within the outer delivery device channel; means at a proximal end region of the applicator for forming an interference fit between the outer delivery device and inner plunger device substantially only when the elongate plunger element is fully inserted within the outer delivery device channel; and packaging for the endoscopic fluid applicator; characterized in that the inner plunger device is entirely removable from the outer delivery device and the outer delivery device and the inner plunger device are pre-assembled with said interference fit within the package, the interference fit being sufficient to substantially prevent further movement of the inner plunger device relative to the outer delivery device absent exertion of a predetermined amount of force by a user. an outer delivery device including a handle at a proximal end and an elongate tubular element extending outwardly from the handle to a distal end, wherein the outer delivery device has a channel extending therethrough between the proximal and distal ends; an inner plunger device including a handle element at a proximal end and an elongate plunger element extending outwardly from the handle to a distal end, wherein the elongate plunger element is sized and shaped so as to be slidably receivable within the outer delivery device channel; means at a proximal end region of the applicator for forming an interference fit between the outer delivery device and inner plunger device substantially only when the elongate plunger element is fully inserted within the outer delivery device channel; and packaging for the endoscopic fluid applicator; characterized in that the inner plunger device is entirely removable from the outer delivery device and the outer delivery device and the inner plunger device are pre-assembled with said interference fit within the package, the interference fit being sufficient to substantially prevent further movement of the inner plunger device relative to the outer delivery device absent exertion of a predetermined amount of force by a user.
An applicator device (1, 21) for applying a cosmetic substance, comprising an applicator unit (2, 22) suitable for accommodating and applying the cosmetic substance, and a handle unit (3, 23) coupled to the applicator unit (2, 22) and configured for manually handling the applicator device (1, 21), wherein the handle unit (3, 23) comprises at least one handle member (4, 24), characterized in that the handle member (4, 24) is coupled to the applicator unit (2, 22) in such a way that an elastic deformation in the handle member (4, 24) caused by manual action thereon causes a change in the rotational angle of the applicator unit (2, 22) with respect to the axial direction of the handle unit (3, 23) and/or the shape of the applicator unit (2, 22).