A system for producing image data regarding a volumetric representation of a planning target volume within a patient's body, the system comprising: at least one active marker that is implantable within the patient; sensors positioned to receive an electromagnetic location signal that is broadcast by the active marker; a signal processing component; an imaging system; a system interface operably coupled with the signal processing component and also operably coupled with the imaging system; and a feedback link between the system interface and the imaging system, wherein the signal processing component and the imaging system are configured to concurrently produce and transmit to the system interface real-time localization data corresponding to the location signal and raw image data regarding the planning target volume, respectively, wherein the imaging system is further configured to use processing algorithms to construct at least one of image frames and image slices, wherein the system interface is configured to: receive the real-time localization data from the signal processing component and the raw image data from the imaging system, bin the raw image data based on the real-time location data, communicate a feedback signal to the imaging system over the feedback link, and in response to a location shift of the planning target volume out of detection range, alert the imaging system of the location shift using the feedback signal, and wherein the imaging system is further configured to halt operation or adjust image processing based on the feedback signal. at least one active marker that is implantable within the patient; sensors positioned to receive an electromagnetic location signal that is broadcast by the active marker; a signal processing component; an imaging system; a system interface operably coupled with the signal processing component and also operably coupled with the imaging system; and a feedback link between the system interface and the imaging system, wherein the signal processing component and the imaging system are configured to concurrently produce and transmit to the system interface real-time localization data corresponding to the location signal and raw image data regarding the planning target volume, respectively, wherein the imaging system is further configured to use processing algorithms to construct at least one of image frames and image slices, wherein the system interface is configured to: receive the real-time localization data from the signal processing component and the raw image data from the imaging system, bin the raw image data based on the real-time location data, communicate a feedback signal to the imaging system over the feedback link, and in response to a location shift of the planning target volume out of detection range, alert the imaging system of the location shift using the feedback signal, and wherein the imaging system is further configured to halt operation or adjust image processing based on the feedback signal. receive the real-time localization data from the signal processing component and the raw image data from the imaging system, bin the raw image data based on the real-time location data, communicate a feedback signal to the imaging system over the feedback link, and in response to a location shift of the planning target volume out of detection range, alert the imaging system of the location shift using the feedback signal, and wherein the imaging system is further configured to halt operation or adjust image processing based on the feedback signal.