mhurhangee/ep-ind-claims huggingface dataset:
A pharmaceutical composition comprising a recombinant antibody molecule, or an α4-binding fragment thereof, comprising a variable heavy chain and a variable light chain, wherein: (a) the variable heavy chain comprises the variable heavy chain framework sequence from IGHV1-f and the CDRs from the VH chain of murine antibody HP1/2, wherein CDR1 comprises the sequence GFNIKDTYM, CDR2 comprises the sequence RIDPASGDTKYDPKFQV and CDR3 comprises the sequence GMWVSTGYALDF, and amino acid residues at framework positions 24 and 94 of the variable heavy chain according to the Kabat numbering scheme are substituted, wherein the substituted residue at framework position 24 is alanine and the substituted residue at framework position 94 is aspartic acid; (b) the variable light chain comprises the variable light chain framework sequence from IGKV4-1 and the CDRs from the VL chain of murine antibody HP1/2, wherein CDR1 comprises the sequence KASQSVTNDVA, CDR2 comprises the sequence YASNRYT and CDR3 comprises the sequence QQDYSSPYT, and amino acid residues at framework positions 1,67 and 87 of the variable light chain according to the Kabat numbering scheme are substituted, wherein the substituted residue at framework position 1 is serine, the substituted residue at framework position 67 is tyrosine and the substituted residue at framework position 87 is phenylalanine; and wherein the recombinant antibody molecule or the α4-binding fragment thereof binds VLA-4. (a) the variable heavy chain comprises the variable heavy chain framework sequence from IGHV1-f and the CDRs from the VH chain of murine antibody HP1/2, wherein CDR1 comprises the sequence GFNIKDTYM, CDR2 comprises the sequence RIDPASGDTKYDPKFQV and CDR3 comprises the sequence GMWVSTGYALDF, and amino acid residues at framework positions 24 and 94 of the variable heavy chain according to the Kabat numbering scheme are substituted, wherein the substituted residue at framework position 24 is alanine and the substituted residue at framework position 94 is aspartic acid; (b) the variable light chain comprises the variable light chain framework sequence from IGKV4-1 and the CDRs from the VL chain of murine antibody HP1/2, wherein CDR1 comprises the sequence KASQSVTNDVA, CDR2 comprises the sequence YASNRYT and CDR3 comprises the sequence QQDYSSPYT, and amino acid residues at framework positions 1,67 and 87 of the variable light chain according to the Kabat numbering scheme are substituted, wherein the substituted residue at framework position 1 is serine, the substituted residue at framework position 67 is tyrosine and the substituted residue at framework position 87 is phenylalanine;
Injection valve for injecting a medium, in particular for injecting fuel into a combustion chamber, comprising: - a housing with at least one spray opening on an outlet side, - a magnet coil, - a magnet armature which can be moved linearly by way of the magnet coil, - a linearly movable valve needle for opening and closing the spray opening, - a first stop on a side of the magnet armature which faces away from the outlet and a second stop on a side of the magnet armature which faces the outlet, the magnet armature being linearly movable between the first stop and the second stop with respect to the valve needle, and - a guide element which is joined to the valve needle, an outer face of the guide element serving as a guide for the linear movement of the magnet armature, and the second stop being an integral constituent part of the guide element. - a housing with at least one spray opening on an outlet side, - a magnet coil, - a magnet armature which can be moved linearly by way of the magnet coil, - a linearly movable valve needle for opening and closing the spray opening, - a first stop on a side of the magnet armature which faces away from the outlet and a second stop on a side of the magnet armature which faces the outlet, the magnet armature being linearly movable between the first stop and the second stop with respect to the valve needle, and - a guide element which is joined to the valve needle, an outer face of the guide element serving as a guide for the linear movement of the magnet armature, and the second stop being an integral constituent part of the guide element.
Work vehicle which is supported on the ground by sprung elements and is equipped with an arrangement for attenuating a possible pitching oscillation of the work vehicle, during which pitching oscillation of the work vehicle the work vehicle inclines forwards or rearwards, wherein the arrangement comprises means for detecting an expected pitching oscillation of the work vehicle and/or means for detecting a present pitching oscillation of the work vehicle, said means being connected to a speed controller of the work vehicle and/or to a ground profile-determining device and/or to a control apparatus for adjusting an element with respect to the work vehicle, and a control device which is connected to the means and to an actuating for influencing the advancing speed of the work vehicle and which can be operated to actuate automatically the actuator with the effect of attenuating the pitching oscillation in that it slightly accelerates the work vehicle when it is just inclined forwards, in order ultimately to bring about a precisely horizontal orientation of the work vehicle and to reduce or destroy the energy of the pitching oscillation and analogously slightly brakes the work vehicle if it inclines rearwards.
Reverberation chamber with improved electromagnetic field uniformity, comprising a shielded enclosure composed of a floor, side walls (13 to 16) and a ceiling, and an antenna for emitting radiofrequency waves in order to generate inside the enclosure radiation at a lowest usable frequency, characterised in that it further comprises, inside the enclosure, a set (5, 6) of passive and selective elements for absorbing radiofrequencies in a defined frequency band having an upper bound which is said lowest usable frequency of the reverberation chamber, and in that the passive and selective elements for absorbing radiofrequencies are arranged at a distance from the side walls (13 to 16) of the enclosure which is at least equal to half the wavelength corresponding to said lowest usable frequency of the reverberation chamber.
A method performed by a content server for providing content for a content consuming device through a communication network, the method comprising: - receiving a request from a content requesting device to provide the content for the content consuming device; - providing a content query in response to the request, the content query being provided via a content broker to a plurality of storage entities connected to the communication network, the content query identifying a location of the content consuming device; - receiving a downloading request, the downloading request sent in response to the content query in the case that none of the plurality of storage entities currently store the content, wherein the downloading request includes a request to provide the content to one of the plurality of storage entities having been selected based on the location of the content consuming device, - providing the content to the selected storage entity in response to the downloading request; and - providing a notification to the content consuming device regarding a current location of the selected storage entity. - receiving a request from a content requesting device to provide the content for the content consuming device; - providing a content query in response to the request, the content query being provided via a content broker to a plurality of storage entities connected to the communication network, the content query identifying a location of the content consuming device; - receiving a downloading request, the downloading request sent in response to the content query in the case that none of the plurality of storage entities currently store the content, wherein the downloading request includes a request to provide the content to one of the plurality of storage entities having been selected based on the location of the content consuming device, - providing the content to the selected storage entity in response to the downloading request; and - providing a notification to the content consuming device regarding a current location of the selected storage entity.
A method of forming a non-optically detectable identifiable mark at an outer surface of an article formed from a solid state material, said method including the steps of: (i) forming a plurality of recesses within a predetermined region of a photoresist (420, 520) applied to an outer surface (412,512) of an article formed from a solid state material, wherein said plurality of recesses is formed by two-photon absorption lithography and wherein said one or more recesses extend at least partially through the photoresist (420,520) and from an outer surface of the photoresist and towards said outer surface of the article formed from a solid state material (410,510); and (ii) applying an etching process such that at least a portion of the outer surface (412,512) of said article (410,510) is exposed and etched so as to form a plurality of etched portions (416,514) extending into said article (410,510) from the outer surface of the article (410,510) and corresponding to said plurality of recesses; wherein said predetermined region of said photoresist (420,520) defines an identifiable mark to be applied to the outer surface (412,512) of said article (410,510); wherein said plurality of etched portions (416,514) forms the non-optically identifiable mark on the outer surface (412,512) of said article (410,510); and wherein the maximum width of the etched portions (416,514) is less than 200nm such that the identifiable mark is non-optically detectable in the visible light spectrum. (i) forming a plurality of recesses within a predetermined region of a photoresist (420, 520) applied to an outer surface (412,512) of an article formed from a solid state material, wherein said plurality of recesses is formed by two-photon absorption lithography and wherein said one or more recesses extend at least partially through the photoresist (420,520) and from an outer surface of the photoresist and towards said outer surface of the article formed from a solid state material (410,510); and (ii) applying an etching process such that at least a portion of the outer surface (412,512) of said article (410,510) is exposed and etched so as to form a plurality of etched portions (416,514) extending into said article (410,510) from the outer surface of the article (410,510) and corresponding to said plurality of recesses; wherein said predetermined region of said photoresist (420,520) defines an identifiable mark to be applied to the outer surface (412,512) of said article (410,510); wherein said plurality of etched portions (416,514) forms the non-optically identifiable mark on the outer surface (412,512) of said article (410,510); and wherein the maximum width of the etched portions (416,514) is less than 200nm such that the identifiable mark is non-optically detectable in the visible light spectrum.
Waste bin, comprising a bucket and a lid which covers the bucket and is pivotally mounted in the region of an upper rim of the bucket in order to be pivoted open upwards for opening the waste bin, further comprising a pedal arrangement (3, 20) which is arranged in the region of a base of the bucket, and a rod arrangement (8, 12) which connects the pedal arrangement (3, 20) to the lid in order to pivot the lid open by movement of the pedal arrangement (3, 20), the lid being of multi-part construction and having at least two lid portions, each of which is pivotable about its own axis (30, 30'), wherein the lid also has a frame element which is removably and/or pivotally mounted in the region of the upper rim of the bucket and to which the lid portions are pivotally attached, wherein the rod arrangement has a distributor element which is seated on a push rod, wherein the push rod is in operative connection with a pedal, is arranged on a rear side of the bucket and is moved vertically on operation of the pedal, with the result that the distributor element attached to the push rod moves upwards in order to pivot open the lid portions, characterised in that the distributor element has a cross-member and two supporting arms as well as a handle element, and the push rod is arranged in a groove on the rearward outer side of the bucket and is guided on the one hand in a guide clip on a base part and on the other hand in a lead-through in the region of the upper rim of the bucket, wherein on operation of the pedal the supporting arms are thrust upwards in order to pivot open the lid portions.
A cutting tool comprising a tip, a body and a shank for attaching the cutting tool to a tool holder, wherein the cutting tool is configured to be rotatable around a longitudinal axis of the cutting tool and comprises a plurality of grooves, - the body having an outer body surface and a body length in a longitudinal direction, a body shank end arranged towards the shank and a body tip end arranged towards the tip, wherein the body tip end comprises a recess for retaining at least a part of the tip within the recess, - the tip having an outer tip surface, a tip peak and a tip base, wherein a tip groove portion of the plurality of grooves extends on the outer tip surface over a major part of the tip base length and wherein the tip base is attached to the body tip end of the body, characterized in that the plurality of grooves comprise the tip groove portion and a body groove portion, that the plurality of grooves extend substantially continuously over both the outer tip surface and the outer body surface, each groove having a predetermined extension in the longitudinal direction of the cutting tool, and that the body groove portion of each groove extends on the outer body surface over part of the body length, the body groove portion extending over a major part of the body length. - the body having an outer body surface and a body length in a longitudinal direction, a body shank end arranged towards the shank and a body tip end arranged towards the tip, wherein the body tip end comprises a recess for retaining at least a part of the tip within the recess, - the tip having an outer tip surface, a tip peak and a tip base, wherein a tip groove portion of the plurality of grooves extends on the outer tip surface over a major part of the tip base length and wherein the tip base is attached to the body tip end of the body,
A process for producing a hydrophobic nanocomposite of nanocrystalline cellulose and a hydrophobic, polymerized vinyl monomer, in which said polymerized vinyl monomer is grafted on said NCC, comprising polymerization of at least one hydrophobic vinyl monomer in the presence of NCC particles in an aqueous medium.
An apparatus for receiving satellite broadcasting, the apparatus comprising: an RF input unit configured to amplify an inputted satellite broadcasting signal; a local oscillator configured to output a signal at an actual tuning frequency (FTUNE) of a selected channel; a mixer configured to convert an output signal of the RF input unit into a baseband signal by mixing the output signal with the said signal output of the of the local oscillator; and a bandwidth controller configured to vary the bandwidth of each channel using a symbol rate and a center frequency difference of the selected channel; wherein the center frequency difference is an absolute value of a difference between the reference center frequency (FREF) of the selected channel and the actual tuning frequency (FTUNE) output by the local oscillator; and wherein the selected channel symbol rates and the reference center frequency (FREF) are values provided by a central processing unit included in the bandwidth controller. an RF input unit configured to amplify an inputted satellite broadcasting signal; a local oscillator configured to output a signal at an actual tuning frequency (FTUNE) of a selected channel; a mixer configured to convert an output signal of the RF input unit into a baseband signal by mixing the output signal with the said signal output of the of the local oscillator; and a bandwidth controller configured to vary the bandwidth of each channel using a symbol rate and a center frequency difference of the selected channel; wherein the center frequency difference is an absolute value of a difference between the reference center frequency (FREF) of the selected channel and the actual tuning frequency (FTUNE) output by the local oscillator; and wherein the selected channel symbol rates and the reference center frequency (FREF) are values provided by a central processing unit included in the bandwidth controller.
Method for routing incoming or outgoing application data in an NFC system (NFCC, CLINT, HP1, HP2, HP3) comprising an NFC interface circuit (CLINT) performing contactless data sending and receiving, an NFC processor (NFCC) associated with the NFC interface circuit and with at least two host processors (HP1, HP2, HP3) of the NFC processor, wherein the routing of incoming application data received by the interface circuit (CLINT) comprises the steps of: - causing an arbitration point (P2) to analyze first incoming application data ("Select File") so that it identifies the application for which the data are sent to the NFC system, and - causing the arbitration point (P2) to designate a point (Pi, P2) of destination of the application data and of processing of the application located in a host processor (HP1, HP2, HP3), and - routing the following incoming application data to the destination and processing point (Pi, P2), and routing outgoing application data sent by the destination and processing point (Pi, P2) to the NFC interface circuit, characterized in that the arbitration point (P2) for the routing of the incoming application data is located in a host processor of the NFC system, and in that it comprises the steps of: - routing the first incoming application data ("Select File") to the arbitration point (P2) located in a host processor, then re-routing the first incoming application data ("Select File") to the destination and processing point (Pi, P2) designated by the arbitration point. - causing an arbitration point (P2) to analyze first incoming application data ("Select File") so that it identifies the application for which the data are sent to the NFC system, and - causing the arbitration point (P2) to designate a point (Pi, P2) of destination of the application data and of processing of the application located in a host processor (HP1, HP2, HP3), and - routing the following incoming application data to the destination and processing point (Pi, P2), and routing outgoing application data sent by the destination and processing point (Pi, P2) to the NFC interface circuit, - routing the first incoming application data ("Select File") to the arbitration point (P2) located in a host processor, then re-routing the first incoming application data ("Select File") to the destination and processing point (Pi, P2) designated by the arbitration point.
Device for preparing and inserting a transplant or an implant into a living body, in combination with a syringe having a nozzle and a plunger for operating the device, in particular for ophthalmological interventions, and in particular for performing a DMEK operation, wherein the device has a cartridge with two openings (2, 3) at opposite ends, wherein the first opening has a larger diameter than the second opening, wherein the outside edge of the second opening can be inserted into the nozzle of the syringe and the first opening can be fitted to the nozzle of the syringe, so that the transplant or implant is drawn, together with liquid, through the first opening into the cartridge by pulling back the plunger of the syringe connected to the second opening, and the transplant or implant, together with the liquid present inside the device, can be ejected from the cartridge by fitting the first opening to the nozzle of the syringe and pressing liquid into the cartridge by operating the plunger of the syringe, whereby the liquid present inside the device is delivered together with the transplant or implant through a suitable incision into the body of a patient.
A hair dryer, comprising a blower cylinder and a handle, wherein: the blower cylinder is provided with a blowing assembly and an electronic control printed circuit board, PCB, sleeved outside the blowing assembly therein, wherein the electronic control PCB is electrically connected to the blowing assembly, and wherein the electronic control PCB is located outside a main air passage of the blower cylinder and is connected to a heat dissipation structure; the heat dissipation structure comprises a heat dissipation assembly in contact with a heater element of the electronic control PCB, wherein at least a portion of the heat dissipation assembly is located in the main air passage; and the heat dissipation assembly comprises a first heat dissipation sheet, wherein one end of the first heat dissipation sheet is in contact with the heater element of the electronic control PCB, and the other end of the first heat dissipation sheet is located in an air inlet of the blower cylinder. the blower cylinder is provided with a blowing assembly and an electronic control printed circuit board, PCB, sleeved outside the blowing assembly therein, wherein the electronic control PCB is electrically connected to the blowing assembly, and wherein the electronic control PCB is located outside a main air passage of the blower cylinder and is connected to a heat dissipation structure; the heat dissipation structure comprises a heat dissipation assembly in contact with a heater element of the electronic control PCB, wherein at least a portion of the heat dissipation assembly is located in the main air passage; and the heat dissipation assembly comprises a first heat dissipation sheet, wherein one end of the first heat dissipation sheet is in contact with the heater element of the electronic control PCB, and the other end of the first heat dissipation sheet is located in an air inlet of the blower cylinder.
An apparatus for the secure monitoring of a monitored zone of a moving part on a movement of the part in the direction of movement having a plurality of sensors and having an evaluation unit for evaluating the sensors, wherein the sensors are arranged spaced apart from one another transversely to the direction of movement; wherein the sensors form an areal protected field that extends over the width of the part; wherein the sensors are contactlessly acting distance-measuring sensors; and wherein the sensors have a detection beam for detecting objects in the monitored zone, characterized in that the detection beams of the sensors are arranged at an acute angle α with respect to the direction of movement of the part, with the sensors being time of flight sensors; with the moving part being a driverless transport vehicle; and with the movement being the vehicle movement and the direction of movement being the direction of movement of the vehicle.