mhurhangee/ep-ind-claims huggingface dataset:
Method for the prognosis of breast cancer in a breast cancer patient with negative nodal status, said method comprising (a) determining the expression level of at least one first marker gene in a tumor sample from said patient, said at least one first marker gene providing information on whether said tumor is fast proliferating or slow proliferating and wherein said first marker gene is selected from Table 1; followed by (b) determining whether said tumor is a fast proliferating tumor or a slow proliferating tumor, by comparison of said expression level of said first marker gene with a predetermined first threshold level; followed by (c) determining the expression level of at least one second marker gene in a tumor sample of said patient, wherein said second marker gene is specifically expressed in immune cells and wherein said second marker gene is CCL5 and wherein said tumor has been determined as a fast proliferating tumor in step (b); wherein a favorable prognosis is given, if said expression level of said second marker gene is above a predetermined threshold level, or wherein an unfavorable prognosis is given if said expression level of said second marker gene is below a predetermined threshold level. (a) determining the expression level of at least one first marker gene in a tumor sample from said patient, said at least one first marker gene providing information on whether said tumor is fast proliferating or slow proliferating and wherein said first marker gene is selected from Table 1; followed by (b) determining whether said tumor is a fast proliferating tumor or a slow proliferating tumor, by comparison of said expression level of said first marker gene with a predetermined first threshold level; followed by (c) determining the expression level of at least one second marker gene in a tumor sample of said patient, wherein said second marker gene is specifically expressed in immune cells and wherein said second marker gene is CCL5 and wherein said tumor has been determined as a fast proliferating tumor in step (b); wherein a favorable prognosis is given, if said expression level of said second marker gene is above a predetermined threshold level, or wherein an unfavorable prognosis is given if said expression level of said second marker gene is below a predetermined threshold level.
A desktop card printer, comprising: - an external communication link enabling communications with a device external to the desktop card printer; - a plurality of data writers (16A, 16B, 16C, 16D) within the desktop card printer; - a USB hub within the desktop card printer and being connected to the external communication link; - a controller within the desktop card printer and being connected to the external communication link via the USB hub; - at least one of the data writers is a smart card contact; - at least one of the data writers (16A, 16B, 16C) is connected to the controller; and - a smart card coupler within the desktop card printer being connected between the smart card contact and the USB hub, wherein the smart card coupler converts instructions from one form received from the external device via the USB hub into a form used by the smart card contact. - an external communication link enabling communications with a device external to the desktop card printer; - a plurality of data writers (16A, 16B, 16C, 16D) within the desktop card printer; - a USB hub within the desktop card printer and being connected to the external communication link; - a controller within the desktop card printer and being connected to the external communication link via the USB hub; - at least one of the data writers is a smart card contact; - at least one of the data writers (16A, 16B, 16C) is connected to the controller; and - a smart card coupler within the desktop card printer being connected between the smart card contact and the USB hub, wherein the smart card coupler converts instructions from one form received from the external device via the USB hub into a form used by the smart card contact.
A method of forming a laminate, the method comprising: providing a metal substrate including a sintered layer, the sintered layer sintered from bronze particles; electrostatic spraying the metal substrate with a non-fluorinated thermoplastic powder selected from a poly-ether-ether-ketone (PEEK), an ultra-high-molecular-weight polyethylene (UHMWPE), a polyimide, a polyamide, a polyamideimide, or any combination thereof, and covering the bronze particles with the non-fluorinated thermoplastic powder to form a transition layer; spraying the transition layer with a fluorinated thermoplastic powder selected from polytetrafluoroethylene (PTFE), a perfluoroalkoxy polymer, fluorinated ehylene-propylene, polyvinylfluoride, polyvinylidene fluoride (PVDF), polychlorotrifluoroethylene (PCTFE), a polyethylenetetrafluoroethylene (ETFE), a polyethylenechlorotrifluoroethylene (ECTFE), or any combination thereof to form a compound layer; wherein the non-fluorinated thermoplastic powder has an average particle size of at least 1 micron, wherein the fluorinated thermoplastic powder comprises a filler comprising molybdenum disulfide and graphite. providing a metal substrate including a sintered layer, the sintered layer sintered from bronze particles; electrostatic spraying the metal substrate with a non-fluorinated thermoplastic powder selected from a poly-ether-ether-ketone (PEEK), an ultra-high-molecular-weight polyethylene (UHMWPE), a polyimide, a polyamide, a polyamideimide, or any combination thereof, and covering the bronze particles with the non-fluorinated thermoplastic powder to form a transition layer; spraying the transition layer with a fluorinated thermoplastic powder selected from polytetrafluoroethylene (PTFE), a perfluoroalkoxy polymer, fluorinated ehylene-propylene, polyvinylfluoride, polyvinylidene fluoride (PVDF), polychlorotrifluoroethylene (PCTFE), a polyethylenetetrafluoroethylene (ETFE), a polyethylenechlorotrifluoroethylene (ECTFE), or any combination thereof to form a compound layer; wherein the non-fluorinated thermoplastic powder has an average particle size of at least 1 micron, wherein the fluorinated thermoplastic powder comprises a filler comprising molybdenum disulfide and graphite.
A method of manufacturing an organic electronic device, comprising: forming a concavo-convex pattern on at least one surface of a first polymer base layer or a layer of a precursor of the first polymer base layer, and forming a second polymer base layer on the surface of the first polymer base layer or the layer of the precursor thereof having the concavo-convex pattern so as to form a space due to the concavo-convex pattern between the first polymer base layer or the layer of the precursor thereof and the second polymer base layer, and forming an organic electronic element on the first polymer base layer using the first and the second polymer base layers having the space there between as a substrate. forming a concavo-convex pattern on at least one surface of a first polymer base layer or a layer of a precursor of the first polymer base layer, and forming a second polymer base layer on the surface of the first polymer base layer or the layer of the precursor thereof having the concavo-convex pattern so as to form a space due to the concavo-convex pattern between the first polymer base layer or the layer of the precursor thereof and the second polymer base layer, and forming an organic electronic element on the first polymer base layer using the first and the second polymer base layers having the space there between as a substrate.
A screwing tool (1, 100) with a longitudinal axis X comprising, according to its longitudinal direction, a first, drive part, which is designed to receive torque applied by a user or by a tool-holder, and a second, transmission part (8, 108), which is secured in rotation to said first part, and is designed to cooperate with a screw (2, 102), in order to re-transmit to it the torque received, said second part having a peripheral envelope with a generally conical form, the base of which is situated on said first part side, and having three longitudinal concavities (10, 110) with conical generatrices, regularly distributed, defining three identical radial transmission lobes (12, 112), each of which has, in a cross-section perpendicular to said longitudinal direction, a distal tangential portion (14, 114) which extends sensibly according to an arc of a circle and which is extended on both sides by two connection portions (16, 116), each of which is defined by a curve comprising a sensibly radial main part (18, 118) and having a point of inflection before re-joining a proximal joining region (20, 120) which ensures the joining with an adjacent connection portion (16, 116), characterized in that, according to said longitudinal direction, said joining regions (20, 120) have a cone angle which is smaller than the cone angle of the tangential portions, and is sensibly less than 5°, preferably less than 3°.
A prefilled syringe with a syringe cylinder which at one axial side is designed in an open manner and is closed by a plunger, and which comprises a Luer lock connection at the other axial side, said Luer lock connection being integrally formed on a face wall closing off the syringe cylinder, with a flowable medium filled into the syringe cylinder, with a soft-elastic plug which closes at least the Luer and with tamper-evident closure which surrounds to the plug to the outside and is with a predetermined breakage location, wherein the syringe cylinder, the face wall and the Luer lock connection are designed as one piece as a transparent plastic injection moulded part, the tamper-evident closure consists of the same type or similar type of plastic as the syringe cylinder and is welded to the face wall of the syringe cylinder, wherein the weld connection forms the predetermined breakage location and the plug is integrated into the tamper-evident closure.
A luminescent borate comprising: a host borate having a B 9 O 16 -comprising crystal lattice; neodymium and ytterbium present within the host borate; wherein the luminescent borate has a formula MeXB 9 O 16 wherein Me is selected from the group consisting of strontium, barium, or a mixture thereof; and X is a mixture of neodymium and ytterbium; and optionally, one or more substitutable elements present within the host borate, the one or more substitutable elements being different from neodymium and ytterbium, and wherein the optionally substitutable elements are selected from the group consisting of lanthanum, cerium, gadolinium, terbium, and mixtures thereof. a host borate having a B 9 O 16 -comprising crystal lattice; neodymium and ytterbium present within the host borate; wherein the luminescent borate has a formula MeXB 9 O 16 wherein Me is selected from the group consisting of strontium, barium, or a mixture thereof; and X is a mixture of neodymium and ytterbium; and optionally, one or more substitutable elements present within the host borate, the one or more substitutable elements being different from neodymium and ytterbium, and wherein the optionally substitutable elements are selected from the group consisting of lanthanum, cerium, gadolinium, terbium, and mixtures thereof.
Method for detecting the presence of ice crystals in an environment, implemented by a detection device in relative motion with respect to said environment, said method comprising at least: - an emission step, in which at least one optical radiation is emitted by the detection device into the environment; - a reception step, in which at least a portion of the emitted optical radiation is received by the detection device, said at least a portion of the received radiation including rays within a first wavelength band (λ 1) and rays within a second wavelength band (λ 2); wherein the detection method further comprises at least: - a calculation step, in which the detection device calculates a comparison signal (Comp(t)) representative of the contrast, said contrast being obtained from the following formula: Comp t = R λ 2 t − R λ 1 t R λ 2 t + R λ 1 t where R λ1 (t) is the intensity over time t of the rays within the first wavelength band (λ 1) and R λ2 (t) is the intensity over time of the rays within the second wavelength band (λ 2), and - a) a standard deviation calculation step, in which a standard deviation (σ) of the comparison signal (Comp(t)) is calculated, - b) a thresholding step, in which the standard deviation (σ) is compared to a defined threshold, - c) a communication step, in which a signal indicating detection of the presence of ice crystals in the environment is transmitted when the standard deviation (σ) is greater than the defined threshold. - an emission step, in which at least one optical radiation is emitted by the detection device into the environment; - a reception step, in which at least a portion of the emitted optical radiation is received by the detection device, said at least a portion of the received radiation including rays within a first wavelength band (λ 1) and rays within a second wavelength band (λ 2); - a calculation step, in which the detection device calculates a comparison signal (Comp(t)) representative of the contrast, said contrast being obtained from the following formula: Comp t = R λ 2 t − R λ 1 t R λ 2 t + R λ 1 t where R λ1 (t) is the intensity over time t of the rays within the first wavelength band (λ 1) and R λ2 (t) is the intensity over time of the rays within the second wavelength band (λ 2), and - a) a standard deviation calculation step, in which a standard deviation (σ) of the comparison signal (Comp(t)) is calculated, - b) a thresholding step, in which the standard deviation (σ) is compared to a defined threshold, - c) a communication step, in which a signal indicating detection of the presence of ice crystals in the environment is transmitted when the standard deviation (σ) is greater than the defined threshold.
Engine for an aircraft comprising a rotor, an electric motor actuating the rotation of said rotor and an ECU controlling said electric motor, said engine further comprising a hub, said ECU being located in said hub, wherein the rotation of said rotor provides a main flow of air causing the thrust of the engine and said ECU is located within the volume defined by said main flow, wherein said hub comprises one or more fins configured to cool said ECU, for example by forced convection and/or by directing at least part of said main flow toward said ECU, characterized in that: said fins are arranged circumferentially around the entire perimeter of said hub. wherein the rotation of said rotor provides a main flow of air causing the thrust of the engine and said ECU is located within the volume defined by said main flow, wherein said hub comprises one or more fins configured to cool said ECU, for example by forced convection and/or by directing at least part of said main flow toward said ECU, characterized in that: said fins are arranged circumferentially around the entire perimeter of said hub.
A method for detecting colon neoplasia associated with reduced expression or no expression of the vimentin gene, comprising: assaying a sample obtained from a patient for the presence of methylation within a nucleotide sequence as set forth in SEQ ID NO: 2; wherein methylation of said nucleotide sequence is indicative of colon neoplasia.
Process for the preparation of drospirenone, comprising the oxidation of 17α-(3-hydroxypropyl)-6β,7β,15β,16β-dimethylene-5β-androstan-3β,5,17β-triol of formula with an oxidizing agent in an organic solvent in the presence of 2,2,6,6-tetramethylpiperidine-1-oxyl radical or of a derivative thereof and of hydroxylamine, said oxidation being followed by the addition of a protic acid, directly into the vessel where oxidation occurred, to complete the formation of drospirenone of formula characterized in that said oxidizing agent is chosen from the group consisting of oxygen, mixtures of inert gas and oxygen, and air.
An ultra-heavy steel plate with low cracking sensitivity and low yield ratio being the ratio of yield strength to tensile strength, wherein the mass percentages of chemical components of the steel plate are C 0.05-0.09; Si 0.2-0.4; Mn 1.3-1.6; Al 0.02-0.04; Nb 0.03-0.08; V 0.03-0.08; Cr 0.1-0.5; Ni 0.1-0.5; Mo 0.1-0.3; Cu 0.2-0.5; Ti 0.01-0.02; P≤0.015; S≤0.003; N≤0.007, the balance being Fe and inevitable impurities, carbon equivalent is ≤0.43, cold cracking sensitivity coefficient Pcm is ≤0.20, wherein the carbon equivalent Ceq and the cold cracking sensitivity coefficient Pcm are calculated respectively from following equations: Ceq = C + Mn / 6 + Cr + Mo + V / 5 + Ni + Cu / 15 Pcm = C + Si / 30 + Mn + Cu + Cr / 20 + Ni / 60 + Mo / 15 + V / 10 + 5 ⁢ B; wherein the steel plate has a thickness of 40-70 mm, a yield strength of ≥460MPa, a tensile strength of 570-760MPa, a yield ratio of ≤0.80, an elongation rate of ≥17%, Charpy impact energy of ≥150J when it is measured at 1/4 thickness and 1/2 thickness of the steel plates at the temperature of -60°C, a reduction of area in Z direction is ≥35%, which is adapted to be applied in low-temperature environments at -60°C.
A hearing aid device configured to communicate wirelessly with an external device where the hearing aid device comprises a housing with a microphone and an amplifier, where the hearing aid device further comprises an antenna (10, 20) and: further comprising a hook provided with a through-going bore configured to deliver air-borne sound acoustically from a receiver in the housing to an ear mould or dome via a tube connected to the hook, the tube configured to be attached to the distal end of the hook, wherein the antenna (10, 20) extends along a portion of the hook and that the antenna is embedded into the wall of the hook. further comprising a hook provided with a through-going bore configured to deliver air-borne sound acoustically from a receiver in the housing to an ear mould or dome via a tube connected to the hook, the tube configured to be attached to the distal end of the hook, wherein the antenna (10, 20) extends along a portion of the hook and that the antenna is embedded into the wall of the hook.
Commercial vehicle tyre of a radial type of construction with a cross-sectional height of 135 mm to 200 mm, a load index of 121 to 154, a radial-ply casing with at least one casing ply comprising steel cords embedded in rubber and with bead regions comprising bead cores and bead fillers, around which the casing ply runs, thereby forming turn-ups, characterized in that the casing ply is reinforced with steel cords of the construction 1 + 6, wherein the core filament has a diameter (d 1) of 0.19 mm to 0.22 mm and the ply filaments have coinciding diameters (d 2) of 0.17 mm to 0.20 mm, wherein the diameter (d 2) of the ply filaments is less than the diameter (d 1) of the core filament by at least 0.01 mm and wherein, at the crown of the tyre, the steel cords are arranged in the casing ply with 60 epdm to 75 epdm.
A method of a User Equipment, in the following also referred to as UE, the method comprising: operating in a paired spectrum in a serving cell, wherein a multiple downlink bandwidth parts of the serving cell is configured and a downlink bandwidth part among the multiple downlink bandwidth parts is an active downlink bandwidth part; and estimating or deriving a pathloss for a Physical Uplink Shared Channel, in the following also referred to as PUSCH, transmission in an uplink bandwidth part of the serving cell, wherein the pathloss for the PUSCH transmission in the uplink bandwidth part of the serving cell is estimated or derived based on a reference signal in the active downlink bandwidth part of the serving cell. operating in a paired spectrum in a serving cell, wherein a multiple downlink bandwidth parts of the serving cell is configured and a downlink bandwidth part among the multiple downlink bandwidth parts is an active downlink bandwidth part; and estimating or deriving a pathloss for a Physical Uplink Shared Channel, in the following also referred to as PUSCH, transmission in an uplink bandwidth part of the serving cell, wherein the pathloss for the PUSCH transmission in the uplink bandwidth part of the serving cell is estimated or derived based on a reference signal in the active downlink bandwidth part of the serving cell.
Optically sampled Analog-to-Digital Converter comprising - an optical source providing radiation of one single wavelength; - an electro-optic modulator sampling an analogue signal provided at an electrical input; - a de-multiplexer de-multiplexing the optically sampled signal; - photodetectors converting the optically sampled signal into electrical signals; - transimpedance amplifiers amplifying the electrical signals and - electrical analogue-to-digital converters converting the amplified signals into digital signals; whereby except to the optical source all electrical and photonic components are integrated on one chip, characterized by additionally comprising a multi wavelength generator as a ring resonator generating several wavelengths of the single wavelength radiation of the optical source and a chromatic dispersion element shifting the generated several wavelengths in time and introducing different delays to each of the several wavelengths. - an optical source providing radiation of one single wavelength; - an electro-optic modulator sampling an analogue signal provided at an electrical input; - a de-multiplexer de-multiplexing the optically sampled signal; - photodetectors converting the optically sampled signal into electrical signals; - transimpedance amplifiers amplifying the electrical signals and - electrical analogue-to-digital converters converting the amplified signals into digital signals; whereby except to the optical source all electrical and photonic components are integrated on one chip,
A device for storing and feeding of raw materials of fruit and/or vegetables for further processing of these raw materials, such that the device comprises a number of storage and feed units (40, 47/51; 55; 70) for fruit/vegetables and/or pieces of fruit/vegetables, and a bottom element, the storage and feed units (40, 47/51; 55; 70) are situated on a support disc, each of the storage and feed units (40, 47/51; 55; 70) is allocated an outlet aperture in the support disc, and a feed disc is situated below the support disc, characterized in that the feed disc is arranged for rotation relative to the bottom element and is provided with a feed aperture, that the feed disc is rotatable relative to the support disc making it possible for the feed aperture to be brought central to any desired outlet aperture, with means (10, 11, 18) for conveying to a machine for further processing the fruit/vegetables and/or pieces of fruit/vegetables fed, that at least some of the storage and feed units (40; 70) comprise a cylinder (32; 71) which has in it an insert (34; 72) comprising a spiral plane (38; 76), that the insert (34; 72) comprises a further plane (39; 74) situated close to one end of the insert, and that the respective lower edges (41, 42) of the spiral plane (38; 76) and the further plane (39; 74) are situated on opposite sides of a discharge aperture which is accommodated in the bottom of the cylinder (32; 71).