Installation for producing containers, in particular bottles, including at least: - a first protective enclosure delimiting a first zone inside which is arranged at least one unit for blow moulding containers, - a second confinement enclosure that, at least in the part attached to the first adjacent enclosure by a common part, delimits a second sterile zone inside which is arranged at least one unit for filling manufactured containers, - at least one opening that, made in said common part of said first and second enclosures (14, 18), is designed to make possible the transfer of the containers from the blow-moulding unit to the filling unit, - means for sealing said opening that are able to be moved selectively between an open position in which the sealing means allow said transfer of the containers through the opening and a closed position in which the sealing means prevent any transfer by isolating the second enclosure to carry out a decontamination of the filling unit, - a transfer device that includes at least one transfer wheel that is adjacent to said opening for transferring the containers between the blow-moulding unit and the filling unit, said transfer wheel including at least one upper part for transfer of the containers that is mounted to move between at least one first transfer position that is occupied when the installation is in a production mode and a second retracted position that is occupied when the installation is in a decontamination mode, the movement of said upper part of the wheel mounted to move between said transfer and retracted positions being controlled from outside the installation, and - a drive system of the transfer wheel for driving in rotation at least the upper part for transfer of the containers from the wheel when, in the production mode, said upper part occupies said transfer position, characterised in that the installation includes a device for disinfecting the transfer wheel that is controlled from outside the installation for disinfecting, by spraying at least one disinfecting agent, at least the upper part for transfer of the containers from the wheel when, in the decontamination mode, said upper part for transfer of the containers from the wheel occupies the retracted position. - a first protective enclosure delimiting a first zone inside which is arranged at least one unit for blow moulding containers, - a second confinement enclosure that, at least in the part attached to the first adjacent enclosure by a common part, delimits a second sterile zone inside which is arranged at least one unit for filling manufactured containers, - at least one opening that, made in said common part of said first and second enclosures (14, 18), is designed to make possible the transfer of the containers from the blow-moulding unit to the filling unit, - means for sealing said opening that are able to be moved selectively between an open position in which the sealing means allow said transfer of the containers through the opening and a closed position in which the sealing means prevent any transfer by isolating the second enclosure to carry out a decontamination of the filling unit, - a transfer device that includes at least one transfer wheel that is adjacent to said opening for transferring the containers between the blow-moulding unit and the filling unit, said transfer wheel including at least one upper part for transfer of the containers that is mounted to move between at least one first transfer position that is occupied when the installation is in a production mode and a second retracted position that is occupied when the installation is in a decontamination mode, the movement of said upper part of the wheel mounted to move between said transfer and retracted positions being controlled from outside the installation, and - a drive system of the transfer wheel for driving in rotation at least the upper part for transfer of the containers from the wheel when, in the production mode, said upper part occupies said transfer position, characterised in that the installation includes a device for disinfecting the transfer wheel that is controlled from outside the installation for disinfecting, by spraying at least one disinfecting agent, at least the upper part for transfer of the containers from the wheel when, in the decontamination mode, said upper part for transfer of the containers from the wheel occupies the retracted position.