A system comprising: a syringe adapter having a first end and a second end, the first end of the syringe adapter configured to be connected to a first container, the second end of the syringe adapter includes a lock member having an open position and a closed position, wherein the lock member includes a biasing member to engage an external surface of the syringe adapter to create a biasing force that urges the lock member back towards the closed position, wherein the biasing member of the lock member comprises a cantilever spring, the body of the syringe adapter defining a cam surface configured to engage the cantilever spring of the lock member, wherein the cantilever spring extends in an axial direction, and wherein the cam surface extends radially outward from the body of the syringe adapter; and a vial adapter having a first end and a second end, the second end of the vial adapter configured to be connected to a second container, the first end of the vial adapter having a locking surface, the syringe adapter configured to be mated with the vial adapter when the lock member is in the open position, the syringe adapter configured to be locked to the vial adapter when the lock member is in the closed position and positioned adjacent to the locking surface, wherein the lock member includes a pair of projections positioned on opposite sides of the lock member, wherein the syringe adapter includes a pair of corresponding projections configured to engage the pair of radially extending projections of the lock member to retain the lock member to the syringe adapter, and wherein the lock member includes a pair of projections extending axially, wherein the pair of axial projections is configured to engage the external surface of the syringe adapter when the lock member is in the open position, wherein the lock member includes a button that is configured to be engaged by a hand of a user and the lock member is moved from the closed position to the open position by engaging the button of the lock member, wherein the pair of axial projections of the lock member is positioned adjacent the button and the biasing member is positioned between the axial projections. a syringe adapter having a first end and a second end, the first end of the syringe adapter configured to be connected to a first container, the second end of the syringe adapter includes a lock member having an open position and a closed position, wherein the lock member includes a biasing member to engage an external surface of the syringe adapter to create a biasing force that urges the lock member back towards the closed position, wherein the biasing member of the lock member comprises a cantilever spring, the body of the syringe adapter defining a cam surface configured to engage the cantilever spring of the lock member, wherein the cantilever spring extends in an axial direction, and wherein the cam surface extends radially outward from the body of the syringe adapter; and a vial adapter having a first end and a second end, the second end of the vial adapter configured to be connected to a second container, the first end of the vial adapter having a locking surface, the syringe adapter configured to be mated with the vial adapter when the lock member is in the open position, the syringe adapter configured to be locked to the vial adapter when the lock member is in the closed position and positioned adjacent to the locking surface, wherein the lock member includes a pair of projections positioned on opposite sides of the lock member, wherein the syringe adapter includes a pair of corresponding projections configured to engage the pair of radially extending projections of the lock member to retain the lock member to the syringe adapter, and wherein the lock member includes a pair of projections extending axially, wherein the pair of axial projections is configured to engage the external surface of the syringe adapter when the lock member is in the open position, wherein the lock member includes a button that is configured to be engaged by a hand of a user and the lock member is moved from the closed position to the open position by engaging the button of the lock member, wherein the pair of axial projections of the lock member is positioned adjacent the button and the biasing member is positioned between the axial projections.