A bag-in-box assembly comprising: a box having an inner surface and an outer surface, the inner surface defined by inner side walls, the inner surface defining a compartment; a flexible container filled with a flowable material, the flexible container located in the compartment; the flexible container comprising: A. a front panel, a rear panel, a first gusseted side panel, and a second gusseted side panel, the gusseted side panels (18, 20) adjoining the front panel and the rear panel along peripheral seals (132a, 132b, 132c, 132d) to form a chamber; B. each peripheral seal (132a, 132b, 132c, 132d) having: (i) an arcuate body seal inner edge (134a, 134b, 134c, 134d) with opposing ends, (ii) a tapered seal inner edge (136a, 136b, 136c, 136d, 138a, 138b, 138c, 138d) extending from each end of the arcuate body seal inner edge (134a, 134b, 134c, 134d); and C. the flexible container comprises at least one arcuate body seal inner edge (134a, 134b, 134c, 134d) having a radius of curvature from 1.0 mm to 300.0 mm, wherein the bag-in-box assembly further comprises: a top perimeter, a center perimeter, and a bottom perimeter; an aggregate contact length at each perimeter (510, 530, 550), the aggregate contact length being a sum of an extent of touch between an outer surface of the flexible container and the inner side walls of the box as measured along a single perimeter, wherein: (i) a top aggregate contact length is from 50% to 90% of the top perimeter; (ii) a center aggregate contact length is from 5% to 50% of the center perimeter; and (iii) a bottom aggregate contact length is from 50% to 90% of the bottom perimeter. a box having an inner surface and an outer surface, the inner surface defined by inner side walls, the inner surface defining a compartment; a flexible container filled with a flowable material, the flexible container located in the compartment; the flexible container comprising: A. a front panel, a rear panel, a first gusseted side panel, and a second gusseted side panel, the gusseted side panels (18, 20) adjoining the front panel and the rear panel along peripheral seals (132a, 132b, 132c, 132d) to form a chamber; B. each peripheral seal (132a, 132b, 132c, 132d) having: (i) an arcuate body seal inner edge (134a, 134b, 134c, 134d) with opposing ends, (ii) a tapered seal inner edge (136a, 136b, 136c, 136d, 138a, 138b, 138c, 138d) extending from each end of the arcuate body seal inner edge (134a, 134b, 134c, 134d); and C. the flexible container comprises at least one arcuate body seal inner edge (134a, 134b, 134c, 134d) having a radius of curvature from 1.0 mm to 300.0 mm, A. a front panel, a rear panel, a first gusseted side panel, and a second gusseted side panel, the gusseted side panels (18, 20) adjoining the front panel and the rear panel along peripheral seals (132a, 132b, 132c, 132d) to form a chamber; B. each peripheral seal (132a, 132b, 132c, 132d) having: (i) an arcuate body seal inner edge (134a, 134b, 134c, 134d) with opposing ends, (ii) a tapered seal inner edge (136a, 136b, 136c, 136d, 138a, 138b, 138c, 138d) extending from each end of the arcuate body seal inner edge (134a, 134b, 134c, 134d); and (i) an arcuate body seal inner edge (134a, 134b, 134c, 134d) with opposing ends, (ii) a tapered seal inner edge (136a, 136b, 136c, 136d, 138a, 138b, 138c, 138d) extending from each end of the arcuate body seal inner edge (134a, 134b, 134c, 134d); and C. the flexible container comprises at least one arcuate body seal inner edge (134a, 134b, 134c, 134d) having a radius of curvature from 1.0 mm to 300.0 mm, wherein the bag-in-box assembly further comprises: a top perimeter, a center perimeter, and a bottom perimeter; an aggregate contact length at each perimeter (510, 530, 550), the aggregate contact length being a sum of an extent of touch between an outer surface of the flexible container and the inner side walls of the box as measured along a single perimeter, wherein: (i) a top aggregate contact length is from 50% to 90% of the top perimeter; (ii) a center aggregate contact length is from 5% to 50% of the center perimeter; and (iii) a bottom aggregate contact length is from 50% to 90% of the bottom perimeter. a top perimeter, a center perimeter, and a bottom perimeter; an aggregate contact length at each perimeter (510, 530, 550), the aggregate contact length being a sum of an extent of touch between an outer surface of the flexible container and the inner side walls of the box as measured along a single perimeter, wherein: (i) a top aggregate contact length is from 50% to 90% of the top perimeter; (ii) a center aggregate contact length is from 5% to 50% of the center perimeter; and (iii) a bottom aggregate contact length is from 50% to 90% of the bottom perimeter. (i) a top aggregate contact length is from 50% to 90% of the top perimeter; (ii) a center aggregate contact length is from 5% to 50% of the center perimeter; and (iii) a bottom aggregate contact length is from 50% to 90% of the bottom perimeter.