A compound of the formula wherein: A is X and Y are independently selected from hydrogen, (C 1 -C 6)alkyl, (C 3 -C 8)cycloalkyl, or an optionally halogen substitutedgroup selected from phenyl, biphenyl, indanyl, 1-naphtyl, 2-naphtyl and tetrahydronaphtyl, pyridyl, pyrimidinyl, pyrazinyl, pyridazinyl, triazinyl, furyl, quinolyl, isoquinolyl, thienyl, imidazolyl, thiazolyl, indolyl, pyrroyl, oxazolyl, benzofuryl, benzothienyl, benzthiazolyl, isoxazolyl, pyrazolyl, triazolyl, tetrazolyl, indazolyl, 1,2,4-thiadiazolyl, isothiazolyl, purinyl, carbazolyl, benzimidazolyl, indolinyl, benzodioxolanyl, benzodioxane, and a stable 3-, 4-, 5-, 6- or 7-membered monocyclic ring that is saturated, partially saturated or fully saturated and that contains carbon atoms and 1, 2, 3 or 4 heteroatoms independently selected from the group consisting of N, O and S; Z is hydrogen, halogen, -OH, (C 1 -C 6)alkyl or (C 1 -C 6)alkoxy; R 1 is, independently at each occurrence, one or more hydrogen, halogen, -CN,-OR 4, -NR 3 R 4, -CONR 3 R 4, -COOH, -OCONR 3 R 4, -NR 6 OCOR 3, -NR 6 CONR 3 R 4,-NR 6 SO 2 NR 3 R 4, -NR 6 SO 2 R 4, optionally hydroxy-substituted (C 1 -C 6)alkyl, (C 2 -C 6)alkenyl, (C 2 -C 6)alkynyl, (C 1 -C 6)alkoxy, (C 3 -C 8)cycloalkyl, (C 3 -C 8)cycloalkyl (C 1 -C 6)alkyl, (C 3 -C 8)cycloalkyl-CO-, (C 3 -C 8)cycloalkyl-SO 2 -, aryl (C 1 -C 6)alkoxy-, (C 3 -C 8)cycloalkyl (C 1 -C 6)alkoxy-, heterocyclyl-CO-, (C 1 -C 6)alkyl-SO 2 -, -NR 6 SO 2 - (C 1 -C 6)alkyl, - NR 6 SO 2 -heterocyclo, (C 1 -C 6)alkyl-NR 6 SO 2 - or heterocyclo-NR 6 SO 2 -; R 2 is hydrogen, halogen, -CN, OH, (C 1 -C 6)alkyl, (C 3 -C 8)cycloalkyl, (C 1 -C 6) alkoxy, (C 1 -C 6)alkyl-SO 2 -, or aryl-SO 2 -; R 3 is hydrogen, (C 1 -C 6)alkyl, (C 3 -C 8)cycloalkyl, (C 2 -C 6)alkenyl, (C 2 -C 6)alkynyl, cyano(C 1 -C 6)alkyl, hydroxy(C 1 -C 6)alkyl, aryl, aryl(C 1 -C 6)alkyl, aryloxy(C 1 -C 6)alkyl, (C 1 -C 6)alkyl-SO 2 -, heterocyclyl, heterocyclyl(C 1 -C 6)alkyl, heteroaryl or heteroaryl(C 1 -C 6)alkyl; R 4 is hydrogen, (C 1 -C 6)alkyl or (C 3 -C 8)cycloalkyl; R 6 is hydrogen or (C 1 -C 6)alkyl; R 7 is hydrogen, (C 1 -C 6)alkyl, haloalkyl, -OR 4, CN, -CONH 2 or halogen; or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof. X and Y are independently selected from hydrogen, (C 1 -C 6)alkyl, (C 3 -C 8)cycloalkyl, or an optionally halogen substitutedgroup selected from phenyl, biphenyl, indanyl, 1-naphtyl, 2-naphtyl and tetrahydronaphtyl, pyridyl, pyrimidinyl, pyrazinyl, pyridazinyl, triazinyl, furyl, quinolyl, isoquinolyl, thienyl, imidazolyl, thiazolyl, indolyl, pyrroyl, oxazolyl, benzofuryl, benzothienyl, benzthiazolyl, isoxazolyl, pyrazolyl, triazolyl, tetrazolyl, indazolyl, 1,2,4-thiadiazolyl, isothiazolyl, purinyl, carbazolyl, benzimidazolyl, indolinyl, benzodioxolanyl, benzodioxane, and a stable 3-, 4-, 5-, 6- or 7-membered monocyclic ring that is saturated, partially saturated or fully saturated and that contains carbon atoms and 1, 2, 3 or 4 heteroatoms independently selected from the group consisting of N, O and S; Z is hydrogen, halogen, -OH, (C 1 -C 6)alkyl or (C 1 -C 6)alkoxy; R 1 is, independently at each occurrence, one or more hydrogen, halogen, -CN,-OR 4, -NR 3 R 4, -CONR 3 R 4, -COOH, -OCONR 3 R 4, -NR 6 OCOR 3, -NR 6 CONR 3 R 4,-NR 6 SO 2 NR 3 R 4, -NR 6 SO 2 R 4, optionally hydroxy-substituted (C 1 -C 6)alkyl, (C 2 -C 6)alkenyl, (C 2 -C 6)alkynyl, (C 1 -C 6)alkoxy, (C 3 -C 8)cycloalkyl, (C 3 -C 8)cycloalkyl (C 1 -C 6)alkyl, (C 3 -C 8)cycloalkyl-CO-, (C 3 -C 8)cycloalkyl-SO 2 -, aryl (C 1 -C 6)alkoxy-, (C 3 -C 8)cycloalkyl (C 1 -C 6)alkoxy-, heterocyclyl-CO-, (C 1 -C 6)alkyl-SO 2 -, -NR 6 SO 2 - (C 1 -C 6)alkyl, - NR 6 SO 2 -heterocyclo, (C 1 -C 6)alkyl-NR 6 SO 2 - or heterocyclo-NR 6 SO 2 -; R 2 is hydrogen, halogen, -CN, OH, (C 1 -C 6)alkyl, (C 3 -C 8)cycloalkyl, (C 1 -C 6) alkoxy, (C 1 -C 6)alkyl-SO 2 -, or aryl-SO 2 -; R 3 is hydrogen, (C 1 -C 6)alkyl, (C 3 -C 8)cycloalkyl, (C 2 -C 6)alkenyl, (C 2 -C 6)alkynyl, cyano(C 1 -C 6)alkyl, hydroxy(C 1 -C 6)alkyl, aryl, aryl(C 1 -C 6)alkyl, aryloxy(C 1 -C 6)alkyl, (C 1 -C 6)alkyl-SO 2 -, heterocyclyl, heterocyclyl(C 1 -C 6)alkyl, heteroaryl or heteroaryl(C 1 -C 6)alkyl; R 4 is hydrogen, (C 1 -C 6)alkyl or (C 3 -C 8)cycloalkyl; R 6 is hydrogen or (C 1 -C 6)alkyl; R 7 is hydrogen, (C 1 -C 6)alkyl, haloalkyl, -OR 4, CN, -CONH 2 or halogen; or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof.