mhurhangee/ep-ind-claims huggingface dataset:
A composition comprising: a platelet cell; a chemical linker moiety; and a therapeutic agent; wherein the therapeutic agent is covalently linked to the platelet cell through the chemical linker moiety; and wherein the therapeutic agent is an immunotherapeutic agent, wherein the immunotherapeutic agent is selected from an anti-PDLl antibody, an anti-PDl antibody, an anti-CTLA4 antibody, an anti-CD47 antibody, or a combination thereof. a platelet cell; a chemical linker moiety; and a therapeutic agent; wherein the therapeutic agent is covalently linked to the platelet cell through the chemical linker moiety; and wherein the therapeutic agent is an immunotherapeutic agent, wherein the immunotherapeutic agent is selected from an anti-PDLl antibody, an anti-PDl antibody, an anti-CTLA4 antibody, an anti-CD47 antibody, or a combination thereof.
An apparatus for unfolding a depth image, the apparatus comprising: a processor to control one or more processor-executable units: an input unit to receive inputted multiple depth images with respect to a same scene, the multiple depth images being photographed based on different modulation frequencies; a depth fold estimator to estimate a number of depth folds based on a distance between multiple three-dimensional points of multiple pixels indicating the same location of the scene in the multiple depth images; and an output unit to output the multiple depth images from which one or more depth folds have been removed based on the estimated number of depth folds; characterised in that the depth fold estimator sums smallest distances between the multiple 3D points while changing a number of depth folds with respect to the multiple 3D points corresponding to the multiple pixels indicating the same location of the scene, and estimates a number of depth folds of when the sum is a minimal value, as an actual number of depth folds. an input unit to receive inputted multiple depth images with respect to a same scene, the multiple depth images being photographed based on different modulation frequencies; a depth fold estimator to estimate a number of depth folds based on a distance between multiple three-dimensional points of multiple pixels indicating the same location of the scene in the multiple depth images; and an output unit to output the multiple depth images from which one or more depth folds have been removed based on the estimated number of depth folds; characterised in that the depth fold estimator sums smallest distances between the multiple 3D points while changing a number of depth folds with respect to the multiple 3D points corresponding to the multiple pixels indicating the same location of the scene, and estimates a number of depth folds of when the sum is a minimal value, as an actual number of depth folds.
Harvesting device, which is intended for arranging on a vehicle, for fruit-bearing plants, in particular for grapes on vines planted in rows, wherein the harvesting device is designed to be movable along the fruit-bearing plants in the direction of travel and working direction and has a plurality of shaking rods (20, 20a, 20b) extending parallel to the direction of travel and arranged spaced apart one above another, wherein the shaking rods are in each case connected at a first end for conjoint rotation to a drive element, which, in turn, is rotatably mounted about its longitudinal axis in the harvesting device and extends vertically along a plurality of shaking rods (20, 20a, 20b), wherein the drive element is drivable in a rotational movement oscillating over a certain angular range about its longitudinal axis, as a result of which the shaking rods (20, 20a, 20b), which are connected to the drive element for conjoint rotation, perform a reciprocating shaking movement, which is directed at the plants, in a horizontal plane and transversely to its longitudinal extent, characterized in that the connection for conjoint rotation between the drive element and the first end of the respective shaking rod (20, 20a, 20b) is designed as a releasable locking mechanism, which is remotely actuable by means of hydraulically, electromechanically or electromagnetically driven actuators (30, 41, 49), of a rotatable mounting of the shaking rod (20, 20a, 20b) about the longitudinal axis of the drive element, the shaking rod (20, 20a, 20b) being fixable relative to the drive element.
Construction element (1a, 1b, 1c, 1d, 1e, 1f) of brick, breeze block or stone block type, having, in cross-section, a generally rectangular quadrilateral form and comprising two transverse lateral faces (2, 3a-3c) and two longitudinal lateral faces (4a-4c, 5a-5c), the construction element forming a wall-tying element which comprises at least one through orifice intended to receive a vertical wall tie of metal reinforcement type, the four lateral faces (2, 3a-3c, 4a, 4b, 4ba, 4bb, 4c, 5a-5c) of the wall-tying element each extending in a plane parallel to the axis of the through orifice, the construction element having a first clearance (9, 9c) formed in a wall of the element on one of its longitudinal lateral faces (4b, 4ba, 4bb-4c), characterized in that said first clearance extends to an edge of said construction element.
Method for measuring a wall thickness (b) in hollow valves with and without a hollow valve head, in which - a wall thickness (b 2) is determined in the region of a chamfer, which is a transition between a valve shaft and the valve head, by means of at least one ultrasonic sensor, wherein the ultrasonic sensor is positioned at a point of the chamfer at which an inner tangent in the cavity runs parallel to an outer tangent on the chamfer and wherein the ultrasonic sensor is oriented relative to the tangents (10, 11) such that the emitted ultrasound is introduced to the surface in a perpendicular manner. - a wall thickness (b 2) is determined in the region of a chamfer, which is a transition between a valve shaft and the valve head, by means of at least one ultrasonic sensor, wherein the ultrasonic sensor is positioned at a point of the chamfer at which an inner tangent in the cavity runs parallel to an outer tangent on the chamfer and wherein the ultrasonic sensor is oriented relative to the tangents (10, 11) such that the emitted ultrasound is introduced to the surface in a perpendicular manner.
A toothbrush having a handle and a toothbrush head at whose top side first, second, and third cleaning elements (912, 914, 1928) are provided for cleaning teeth, wherein the first cleaning elements have first bristle tufts, which, as single tufts, each have a long and a short side and thus an approximately rectangular base in cross-section, wherein a longitudinal center axis of the toothbrush proceeds from a free handle end to a free head end and a transverse axis is arranged perpendicular to the longitudinal center axis, wherein several first bristle tufts are arranged on the top side in such a way that their combined circumferential surface forms an approximately square or rhombic base, wherein two corners of the square or rhombus of the first cleaning elements are arranged along a longitudinal center axis of the toothbrush and the two additional corners of the square or rhombus of the first cleaning elements are arranged on an axis transverse to the longitudinal center axis, and wherein the first cleaning elements surround the second cleaning elements, and the first cleaning elements are designed to be longer than the second cleaning elements, resulting in a trough-like toothpaste receiving zone formed by the free ends of the second cleaning elements and the surrounding end areas of the first cleaning elements, and wherein the second cleaning elements have second bristle tufts with a circular tuft cross-section, and the first bristle tufts enclose the second bristle tufts.
A computer-implemented method for compressing a three-dimensional modeled object, comprising: - providing a mesh of the three-dimensional modeled object; - storing connectivity data of the mesh of the three-dimensional modeled object characterised by - parameterizing (u,v) the mesh in a two-dimensional plane, the parameterization of the mesh resulting in a set of vertices having two-dimensional coordinates; - providing a grid on the two-dimensional plane; and - modifying the two-dimensional coordinates of each vertex by assigning one vertex to one intersection of the grid, the set of vertices with modified coordinates forming a 2D array of vertices; and - applying a compression scheme on the 2D array of vertices. - providing a mesh of the three-dimensional modeled object; - storing connectivity data of the mesh of the three-dimensional modeled object characterised by - parameterizing (u,v) the mesh in a two-dimensional plane, the parameterization of the mesh resulting in a set of vertices having two-dimensional coordinates; - providing a grid on the two-dimensional plane; and - modifying the two-dimensional coordinates of each vertex by assigning one vertex to one intersection of the grid, the set of vertices with modified coordinates forming a 2D array of vertices; and - applying a compression scheme on the 2D array of vertices.
A method of inactivating a virus in a sample comprising a protein component comprising: (a) providing a sample comprising the protein component, wherein the sample is an effluent stream from a purification step and the sample is known or suspected to contain a virus; (b) adding a protectant to the effluent stream to form a stabilized mixture; (c) measuring the absorbance of the stabilized mixture; (d) passing the stabilized mixture through a device configured to provide continuous exposure to UV light such that a target dose of UV light under which the virus is inactivated is delivered to the mixture; and (e) based on the absorbance measurement, adjusting the UV light exposure such that the target dose of UV light is continually delivered to the stabilized mixture passing through the device, wherein steps (c), (d) and (e) are conducted as part of an automated feedback loop. (a) providing a sample comprising the protein component, wherein the sample is an effluent stream from a purification step and the sample is known or suspected to contain a virus; (b) adding a protectant to the effluent stream to form a stabilized mixture; (c) measuring the absorbance of the stabilized mixture; (d) passing the stabilized mixture through a device configured to provide continuous exposure to UV light such that a target dose of UV light under which the virus is inactivated is delivered to the mixture; and (e) based on the absorbance measurement, adjusting the UV light exposure such that the target dose of UV light is continually delivered to the stabilized mixture passing through the device, wherein steps (c), (d) and (e) are conducted as part of an automated feedback loop.
A method for tracking a reference picture in a video decoder, comprising: receiving a bitstream; decoding a portion of the bitstream to produce a decoded reference picture; determining a designated picture; tracking the decoded reference picture in a decoded picture buffer based on a designated picture, wherein tracking the decoded reference picture comprises: determining a picture order count based on the designated picture; receiving a wrap indicator from an encoder indicating a transition between two sets of pictures, the wrap indicator being a one bit flag; determining a current picture order count cycle parameter based on the designated picture, wherein the picture order count cycle parameter references sets of pictures including reference pictures, and wherein determining the current picture order count cycle parameter includes updating a previous picture order count cycle parameter after receiving the wrap indicator; obtaining the decoded reference picture according to the POC and the picture order count cycle parameter; and decoding a picture based on the decoded reference picture. receiving a bitstream; decoding a portion of the bitstream to produce a decoded reference picture; determining a designated picture; tracking the decoded reference picture in a decoded picture buffer based on a designated picture, wherein tracking the decoded reference picture comprises: determining a picture order count based on the designated picture; receiving a wrap indicator from an encoder indicating a transition between two sets of pictures, the wrap indicator being a one bit flag; determining a current picture order count cycle parameter based on the designated picture, wherein the picture order count cycle parameter references sets of pictures including reference pictures, and wherein determining the current picture order count cycle parameter includes updating a previous picture order count cycle parameter after receiving the wrap indicator; obtaining the decoded reference picture according to the POC and the picture order count cycle parameter; and decoding a picture based on the decoded reference picture. determining a picture order count based on the designated picture; receiving a wrap indicator from an encoder indicating a transition between two sets of pictures, the wrap indicator being a one bit flag; determining a current picture order count cycle parameter based on the designated picture, wherein the picture order count cycle parameter references sets of pictures including reference pictures, and wherein determining the current picture order count cycle parameter includes updating a previous picture order count cycle parameter after receiving the wrap indicator; obtaining the decoded reference picture according to the POC and the picture order count cycle parameter; and decoding a picture based on the decoded reference picture.
A connector, comprising: a first connector part to connect a first cable; a second connector part to connect a second cable and to fit with the first connector part, thereby ensuring electrical connection between the first cable and second cable; and a housing to hold the second connector part rotatably around an axial direction of the second cable; and in a state that the first connector part fits with the second connector part, the first connector part and second connector part are rotatable with respect to the housing, wherein the first connector part comprises a male electrode to connect the first cable, and a cylindrical part provided around the male electrode; the second connector part comprises a female electrode to connect the second cable, and a columnar part provided with the female electrode inside, and housed in the cylindrical part; and the housing includes a housing part to house the columnar part rotatably around the axial direction and for fixing the second connector part to the housing rotatably around the axial direction, the columnar part is provided with an annular flange extending outward in a radial direction, and the housing has a through-hole to pass through the columnar part in a state that a part of the columnar part is inserted into the housing part, and is provided with a fixing plate to place the annular flange on a surface of the housing. a first connector part to connect a first cable; a second connector part to connect a second cable and to fit with the first connector part, thereby ensuring electrical connection between the first cable and second cable; and a housing to hold the second connector part rotatably around an axial direction of the second cable;
A process comprising combining a) a solution comprising at least one substance selected from the group consisting of: K 2 HPO 4, an aluminum phosphate, oxalic acid, or a combination thereof, with b) a Mn 4+ doped phosphor of formula I in solid form; Ax [MF y]:Mn 4+ I and isolating a stabilized Mn 4+ doped phosphor in solid form; wherein A is Li, Na, K, Rb, Cs, or a combination thereof; M is Si, Ge, Sn, Ti, Zr, Al, Ga, In, Sc, Y, La, Nb, Ta, Bi, Gd, or a combination thereof; x is the absolute value of the charge of the [MF y] ion; y is 5, 6 or 7, further comprising, prior to combining with at the least one substance, contacting the Mn 4+ doped phosphor of formula I with a fluorine-containing oxidizing agent in gaseous form at an elevated temperature, to form a product phosphor. and isolating a stabilized Mn 4+ doped phosphor in solid form; wherein A is Li, Na, K, Rb, Cs, or a combination thereof; M is Si, Ge, Sn, Ti, Zr, Al, Ga, In, Sc, Y, La, Nb, Ta, Bi, Gd, or a combination thereof; x is the absolute value of the charge of the [MF y] ion; y is 5, 6 or 7, further comprising, prior to combining with at the least one substance, contacting the Mn 4+ doped phosphor of formula I with a fluorine-containing oxidizing agent in gaseous form at an elevated temperature, to form a product phosphor.
A method of manufacturing a plastic lens comprising: discharging a plastic lens starting material liquid from a tip opening of a discharge hole of a mixing and discharging part, the mixing and discharging part comprising a mixing chamber comprising a stirring means that stirs a plastic lens starting material liquid comprising multiple polymerizable components and the discharge hole communicating with the mixing chamber; casting the plastic lens starting material liquid that has been discharged into a casting mold, the casting mold comprising a cavity and a casting hole for introducing the plastic lens starting material into the cavity, and the plastic lens starting material being cast into the casting mold through a tip opening of the casting hole; and polymerizing the plastic lens starting material that has been cast within the casting mold to obtain a polymerized product, wherein the plastic lens starting material liquid is discharged through the discharge hole while maintaining the casting mold in a state in which the tip opening of the casting hole is separated from the tip opening of the discharge hole, characterized in that a posture of the casting mold is then changed from that state to bring the tip opening of the casting hole closer to the tip opening of the discharge hole to begin the casting, as well as before the plastic lens starting material liquid that has been cast reaches an interior of the cavity, the tip opening of the casting hole and the tip opening of the discharge hole are connected to secure the casting mold, and the secured state is maintained until the cavity is filled with the plastic lens starting material liquid. discharging a plastic lens starting material liquid from a tip opening of a discharge hole of a mixing and discharging part, the mixing and discharging part comprising a mixing chamber comprising a stirring means that stirs a plastic lens starting material liquid comprising multiple polymerizable components and the discharge hole communicating with the mixing chamber; casting the plastic lens starting material liquid that has been discharged into a casting mold, the casting mold comprising a cavity and a casting hole for introducing the plastic lens starting material into the cavity, and the plastic lens starting material being cast into the casting mold through a tip opening of the casting hole; and polymerizing the plastic lens starting material that has been cast within the casting mold to obtain a polymerized product, wherein
A method of controlling start-up of an internal combustion engine that has a throttle for controlling an intake air amount and performs the start-up through cranking, the method comprising: detecting cranking initiation of the internal combustion engine; detecting an atmospheric pressure at the time of cranking initiation of the internal combustion engine; setting an initial opening based on the atmospheric pressure at the time of cranking initiation, wherein the initial opening is narrower than a predetermined target Idle opening; controlling a throttle opening of the throttle to the initial opening at the time of cranking initiation; and starting to increase the throttle opening of the throttle from the initial opening toward the predetermined target idle opening at a predetermined timing after cranking initiation, wherein the initial opening is set to a lower value as the atmospheric pressure increases, characterized by detecting an engine temperature at the time of cranking initiation of the internal combustion engine, wherein the initial opening is set to a lower value as the engine temperature at the time of cranking initiation increases. detecting cranking initiation of the internal combustion engine; detecting an atmospheric pressure at the time of cranking initiation of the internal combustion engine; setting an initial opening based on the atmospheric pressure at the time of cranking initiation, wherein the initial opening is narrower than a predetermined target Idle opening; controlling a throttle opening of the throttle to the initial opening at the time of cranking initiation; and starting to increase the throttle opening of the throttle from the initial opening toward the predetermined target idle opening at a predetermined timing after cranking initiation, wherein the initial opening is set to a lower value as the atmospheric pressure increases, characterized by detecting an engine temperature at the time of cranking initiation of the internal combustion engine, wherein the initial opening is set to a lower value as the engine temperature at the time of cranking initiation increases.
A 1,5-benzodiazepine derivative represented by formula: (wherein R 1 represents a C 1-6 alkyl group, R 2 represents a phenyl group or a cyclohexyl group, and Y represents a single bond or a C 1-4 alkylene group) or a pharmaceutically acceptable salt thereof, for use in the treatment or prevention of cancer pain at a peroral daily dose for an adult of 50 to 600 mg.
A process for preparing low molecular weight peptide comprising the steps of: a. clarifying 0.5 to 6.5% w/v fish gelatine solution by adjusting pH upto 7 followed by centrifuging the solution followed by membrane filtration to make the solution particle-free by discarding the solid particles; b. desalting the solution as clarified in step (a) through ultrafiltration membrane at temperature in the range of 20 to 55°C in a diafiltration mode till the salt content decreases below 0.05% (w/v) followed by discarding the permeate; c. hydrolyzing the product obtained in step (b) with an enzyme maintaining pH in the range of 7 to 10 and at temperature in the range of 25 to 75°C for period in the range of 3.5 to 4 hr to obtain hydrolysed product; d. filtering the hydrolyzed product of step (c) through ultrafiltration membrane at temperature in the range of 15 to 55°C and concentrating the permeate at temperature in the range of 50 to 100°C under vacuum followed by drying by any conventional means known in the art such as spray drying to obtain peptide powder. a. clarifying 0.5 to 6.5% w/v fish gelatine solution by adjusting pH upto 7 followed by centrifuging the solution followed by membrane filtration to make the solution particle-free by discarding the solid particles; b. desalting the solution as clarified in step (a) through ultrafiltration membrane at temperature in the range of 20 to 55°C in a diafiltration mode till the salt content decreases below 0.05% (w/v) followed by discarding the permeate; c. hydrolyzing the product obtained in step (b) with an enzyme maintaining pH in the range of 7 to 10 and at temperature in the range of 25 to 75°C for period in the range of 3.5 to 4 hr to obtain hydrolysed product; d. filtering the hydrolyzed product of step (c) through ultrafiltration membrane at temperature in the range of 15 to 55°C and concentrating the permeate at temperature in the range of 50 to 100°C under vacuum followed by drying by any conventional means known in the art such as spray drying to obtain peptide powder.