mhurhangee/ep-ind-claims huggingface dataset:
A method for separating biologically active lymphotoxin-β receptor immunoglobulin (LT-β-R-Ig) fusion proteins from biologically inactive LT-β-R-Ig fusion proteins inclusive of the first inactive form of the LT-β-R-Ig fusion protein (inactive-1) and the second inactive form of the LT-β-R-Ig fusion protein (inactive-2), comprising loading a mixture comprising biologically active LT-β-R-Ig fusion proteins and biologically inactive LT-β-R-Ig fusion proteins onto a butyl hydrophobic interaction chromatography resin and contacting the resin with a solution comprising a salt gradient to obtain a first eluate comprising biologically inactive-1 LT-β-R-Ig fusion proteins and a second eluate comprising biologically active LT-β-R-Ig fusion proteins, and wherein the inactive-1 LT-β-R-Ig fusion protein elutes from the butyl hydrophobic interaction chromatography resin at a higher salt concentration than the biologically active LT-β-R-Ig fusion protein, and wherein the inactive-2 LT-β-R-Ig fusion protein remains bound to the butyl resin until stripped off with water.
A composition comprising at least one of the compounds selected from the group consisting of: and or a pharmaceutically acceptable salt, solvate, or stereoisomer thereof, and an effective amount of at least one or more of the following compounds selected from the group consisting of chloroquine; Bafilomycin A1; Avasimibe (CI-1011); olaparib and talazoparib.
A method of determining the sub-divisional error of an encoder apparatus that is configured to measure the position of relatively moveable parts (20, 22) of an apparatus on which an inspection device is mounted, the method comprising: causing the inspection device to inspect a feature providing a reference so as to obtain measurements of the surface of the feature, which comprises relatively moving said relatively moveable parts of the apparatus; and using the measurements of the surface of the feature obtained by the inspection device during said inspection of the feature to determine the encoder apparatus' sub-divisional error. causing the inspection device to inspect a feature providing a reference so as to obtain measurements of the surface of the feature, which comprises relatively moving said relatively moveable parts of the apparatus; and using the measurements of the surface of the feature obtained by the inspection device during said inspection of the feature to determine the encoder apparatus' sub-divisional error.
An E1 and E3 deleted adenovirus for use in a method for inducing a protective response against respiratory pathogens in a mammalian subject in need thereof comprising administering intranasally, 1 or 2 days before exposure to the respiratory pathogen, an effective amount of E1 and E3 deleted adenovirus, with or without encoding a pathogen-derived antigen.
A composition consisting of the alcohol extracts prepared from Fructus Ligustri Lucidi, Herba Ecliptae, Radix Paeoniae Alba and Rhizoma Curcumae Longae, and the water extract of clam; wherein the parts by weight of the respective components are: 20 parts of Fructus Ligustri Lucidi, 15 parts of Herba Ecliptae, 8 parts of Radix Paeoniae Alba, 12 parts of the Rhizoma Curcumae Longae extract, and 8 parts of the clam extract.
A method for controlling concentration of free chlorine using a plurality of electrodes, the method comprising, in order: a first process (i) adjusting a potential of an anode and a potential of a cathode in an aqueous solution comprising chloride ions, thereby increasing a concentration of free chlorine in the aqueous solution; characterized by a second process (ii) adjusting the potential of an anode and the potential of a cathode in the aqueous solution, thereby decreasing a concentration of free chlorine in the aqueous solution; wherein a DC voltage applied between the anode and the cathode in the second process (ii) has a magnitude smaller than that of a DC voltage applied between the anode and the cathode in the first process (i), the respective anode is composed of a respective first portion of the plurality of electrodes, the respective cathode is composed of a respective second portion of the plurality of electrodes, the respective anode and the respective cathode are each respective electrodes in which platinum exists at a surface of the electrodes or which are platinum-coated and a DC voltage of at least 4 V is applied between the anode and the cathode in the first process (i), and a DC voltage within a range from 0.6 V to 3 V is applied between the anode and the cathode in the second process (ii). a first process (i) adjusting a potential of an anode and a potential of a cathode in an aqueous solution comprising chloride ions, thereby increasing a concentration of free chlorine in the aqueous solution; characterized by a second process (ii) adjusting the potential of an anode and the potential of a cathode in the aqueous solution, thereby decreasing a concentration of free chlorine in the aqueous solution; wherein a DC voltage applied between the anode and the cathode in the second process (ii) has a magnitude smaller than that of a DC voltage applied between the anode and the cathode in the first process (i), the respective anode is composed of a respective first portion of the plurality of electrodes, the respective cathode is composed of a respective second portion of the plurality of electrodes, the respective anode and the respective cathode are each respective electrodes in which platinum exists at a surface of the electrodes or which are platinum-coated and a DC voltage of at least 4 V is applied between the anode and the cathode in the first process (i), and a DC voltage within a range from 0.6 V to 3 V is applied between the anode and the cathode in the second process (ii).
A method for adjusting a prosthetic or orthotic device, the method comprising: detecting a stationary position of a user of a prosthetic or orthotic device; identifying with control circuitry operatively coupled to the prosthetic or orthotic device a first location of the prosthetic or orthotic device based on information received at a first time, after detecting the stationary position and while the user remains in the stationary position, from a transmitting source located remotely to the prosthetic or orthotic device; identifying with the control circuitry a second location of the prosthetic or orthotic device based on information received at a second time, after detecting the stationary position and while the user remains in the stationary position, from the transmitting source; calculating a velocity of the prosthetic or orthotic device based on a distance between the first and second locations over a duration of time between the first time and the second time; comparing the calculated velocity to a threshold velocity; and when the calculated velocity of the prosthetic or orthotic device exceeds the threshold velocity, automatically adjusting a state of operation of the prosthetic or orthotic device. identifying with control circuitry operatively coupled to the prosthetic or orthotic device a first location of the prosthetic or orthotic device based on information received at a first time, after detecting the stationary position and while the user remains in the stationary position, from a transmitting source located remotely to the prosthetic or orthotic device; identifying with the control circuitry a second location of the prosthetic or orthotic device based on information received at a second time, after detecting the stationary position and while the user remains in the stationary position, from the transmitting source; calculating a velocity of the prosthetic or orthotic device based on a distance between the first and second locations over a duration of time between the first time and the second time; comparing the calculated velocity to a threshold velocity; and when the calculated velocity of the prosthetic or orthotic device exceeds the threshold velocity, automatically adjusting a state of operation of the prosthetic or orthotic device.
A connector assembly comprising an adaptor and a cap to be connected to each other, wherein the adaptor comprises: - a proximal connection portion configured to be removably connectable to a medical injection device; and - a spike extending distally from the proximal connection portion and around a central axis, wherein the cap comprises a cap body defining an inner cavity extending around the central axis, the inner cavity being open at a proximal end of the cap body and is closed at a distal end of the cap body, wherein the connector assembly is configured such that the cap is removably connected to the adaptor in such a way that the spike is accommodated within the inner cavity, the assembly being characterized in that the adaptor and the cap are made of a plastic material suitable for injection molding and the cap is removably connected to the adaptor by press-fit between the spike and the inner cavity. wherein the adaptor comprises: - a proximal connection portion configured to be removably connectable to a medical injection device; and - a spike extending distally from the proximal connection portion and around a central axis, - a proximal connection portion configured to be removably connectable to a medical injection device; and - a spike extending distally from the proximal connection portion and around a central axis, wherein the cap comprises a cap body defining an inner cavity extending around the central axis, the inner cavity being open at a proximal end of the cap body and is closed at a distal end of the cap body, wherein the connector assembly is configured such that the cap is removably connected to the adaptor in such a way that the spike is accommodated within the inner cavity, the assembly being characterized in that the adaptor and the cap are made of a plastic material suitable for injection molding and the cap is removably connected to the adaptor by press-fit between the spike and the inner cavity.
A motorised transportation apparatus comprising: a platform; a plurality of trucks (124, 128) coupled to the platform, wherein the trucks are longitudinally opposing each other, wherein each of the trucks includes a wheel; a plurality of roller assemblies (136, 138) coupled to the platform, wherein the assemblies are longitudinally opposing each other between the trucks, wherein the assemblies are configured for omnidirectional rotation about a first axis, wherein each of the assemblies includes a roller rolling about a second axis, wherein the first axis is distinct from the second axis, characterised in that at least one of the assemblies (136, 138) comprises a motor, and in that the apparatus further comprises: a slip ring coupled to the motor; a speed controller coupled to the ring; and a power source coupled to the controller. a platform; a plurality of trucks (124, 128) coupled to the platform, wherein the trucks are longitudinally opposing each other, wherein each of the trucks includes a wheel; a plurality of roller assemblies (136, 138) coupled to the platform, wherein the assemblies are longitudinally opposing each other between the trucks, wherein the assemblies are configured for omnidirectional rotation about a first axis, wherein each of the assemblies includes a roller rolling about a second axis, wherein the first axis is distinct from the second axis, characterised in that at least one of the assemblies (136, 138) comprises a motor, and in that the apparatus further comprises: a slip ring coupled to the motor; a speed controller coupled to the ring; and a power source coupled to the controller. a slip ring coupled to the motor; a speed controller coupled to the ring; and a power source coupled to the controller.
Method for the recognition of an actuating movement (G1, G3) for the sensor-controlled activation of a motor vehicle equipment element by means of an actuating device comprising capacitive sensors (S1, S2, S3, S4) with overlapping detection ranges (E1, E2, E4), the method comprising: the determination of a direction of the actuating movement (G1, G3) within the overlapping detection ranges (E1, E2, E4) as a valid direction of movement, and the detection of a movement (G1, G2, G3, G4) through detection ranges (E1, E2, E4) of two capacitive sensors (S1, S2, S3, S4) and the determination of an overall duration (t ges) of the movement (G1, G2, G3, G4) through the detection ranges (E1, E2, E4) of two capacitive sensors (S1, S2, S3, S4), characterised by the detection of an overlap duration (t 12, t 24) of the movement (G1, G2, G3, G4) in an overlapping range (E12, E24) of the detection ranges (E1, E2, E4), the calculation of a quotient from the overlap duration (t 12, t 24) and the overall duration (t ges), the comparison of the quotient to a predetermined limit value which separates a valid range from an invalid range, and the verification that the movement (G1, G2, G3, G4) is an actuating movement (G1, G3) with a valid direction of movement, if the quotient lies within the valid range. the determination of a direction of the actuating movement (G1, G3) within the overlapping detection ranges (E1, E2, E4) as a valid direction of movement, and the detection of a movement (G1, G2, G3, G4) through detection ranges (E1, E2, E4) of two capacitive sensors (S1, S2, S3, S4) and the determination of an overall duration (t ges) of the movement (G1, G2, G3, G4) through the detection ranges (E1, E2, E4) of two capacitive sensors (S1, S2, S3, S4), characterised by the detection of an overlap duration (t 12, t 24) of the movement (G1, G2, G3, G4) in an overlapping range (E12, E24) of the detection ranges (E1, E2, E4), the calculation of a quotient from the overlap duration (t 12, t 24) and the overall duration (t ges), the comparison of the quotient to a predetermined limit value which separates a valid range from an invalid range, and the verification that the movement (G1, G2, G3, G4) is an actuating movement (G1, G3) with a valid direction of movement, if the quotient lies within the valid range.
A seat belt height adjuster for a seatbelt loop, comprising: a positioning mechanism slidable on a guide rail and operable to secure a seatbelt loop in a selected position on the guide rail, the positioning mechanism having a first operating state in which the positioning mechanism is locked to the guide rail a second operating state in which the positioning mechanism able to slide on the guide rail; an actuator operable to control the operating state of the positioning mechanism, the actuator being movable with respect to an actuator support between a first position in which the positioning mechanism is in first operating state and a second position in which the positioning mechanism is in the second operating state; characterised in that a biasing means is configured to bias the actuator against the actuator support, wherein the biasing means applies a restoring force that is distributed across a transverse region of the actuator; wherein the transverse region extends across at least 20% of the width of the actuator, the biasing means is provided integral to the actuator, the biasing means being a spring member comprising of a plurality of first spring elements configured to act through a common spring abutment, and wherein the plurality of first spring elements are linked by a plurality of second transverse spring elements. a positioning mechanism slidable on a guide rail and operable to secure a seatbelt loop in a selected position on the guide rail, the positioning mechanism having a first operating state in which the positioning mechanism is locked to the guide rail a second operating state in which the positioning mechanism able to slide on the guide rail; an actuator operable to control the operating state of the positioning mechanism, the actuator being movable with respect to an actuator support between a first position in which the positioning mechanism is in first operating state and a second position in which the positioning mechanism is in the second operating state; characterised in that a biasing means is configured to bias the actuator against the actuator support, wherein the biasing means applies a restoring force that is distributed across a transverse region of the actuator; wherein the transverse region extends across at least 20% of the width of the actuator, the biasing means is provided integral to the actuator, the biasing means being a spring member comprising of a plurality of first spring elements configured to act through a common spring abutment, and wherein the plurality of first spring elements are linked by a plurality of second transverse spring elements.
An isolated antigen binding protein comprising an immunoglobulin heavy chain variable region and an immunoglobulin light chain variable region, wherein the heavy chain variable region comprises the amino acid sequence of SEQ ID NO: 258 and the light chain variable region comprises the amino acid sequence of SEQ ID NO: 236.
System comprising an insertion-type connector having a housing and at least two contact elements fixed within the housing, and a twisted-pair cable for signal and data transmission, two cores of the twisted-pair cable being electrically conductively connected to the contact elements by means of crimp connections, the housing forming a guide by which the two cores are fixed in a twist which continues the twist of the twisted-pair cable, wherein the at least two contact elements have an elongated shape and are arranged parallel to each other, wherein the housing has at least one guide pin extending transversely to a plane spanned by the longitudinal axes of the contact elements for forming the guide in a guide space, around which guide pin the cores are guided in an arc, wherein the wires are twisted directly to the contact elements, wherein the housing has two housing parts (16, 17) produced by injection moulding, with a division in those side walls which are crossed by the plane spanned by the longitudinal axes of the contact elements, wherein the housing parts (16, 17) have no undercuts with respect to a demoulding direction, and wherein the at least one guide pin is formed by the second housing part.
A light-emitting assembly comprising: a panel having a first side and an opposing second side; the panel is a flooring panel, a ceiling panel or a wall panel and the first side and the second side of the panel are parallel to one another or the first side and the second side of the panel incline toward one another; the panel is a plywood panel, a fiber board panel, a plastic panel or a concrete panel; a plurality of bores extending from the first side to the second side; an LED light source comprising: a circuit board having first side and an opposing second side, the first side of the circuit board adjacent to the first side of the panel; a plurality of LEDs operably connected to the first side of the circuit board; characterized by, a plurality of optical wave guides, each wave guide having a first end and a second end, the first end disposed in one of the bores and the second end optically connected to one of the LEDs the panel has a thickness of from about 15,24 cm (1⁄2') to about 2,54cm (1 "), preferably of about 1,905cm (3⁄4") and the LED, the optical wave guide and the bore are all aligned on an axis that is orthogonal to the first side and the second side of the panel. a panel having a first side and an opposing second side; the panel is a flooring panel, a ceiling panel or a wall panel and the first side and the second side of the panel are parallel to one another or the first side and the second side of the panel incline toward one another; the panel is a plywood panel, a fiber board panel, a plastic panel or a concrete panel; a plurality of bores extending from the first side to the second side; an LED light source comprising: a circuit board having first side and an opposing second side, the first side of the circuit board adjacent to the first side of the panel; a plurality of LEDs operably connected to the first side of the circuit board; characterized by, a plurality of optical wave guides, each wave guide having a first end and a second end, the first end disposed in one of the bores and the second end optically connected to one of the LEDs the panel has a thickness of from about 15,24 cm (1⁄2') to about 2,54cm (1 "), preferably of about 1,905cm (3⁄4") and the LED, the optical wave guide and the bore are all aligned on an axis that is orthogonal to the first side and the second side of the panel. a circuit board having first side and an opposing second side, the first side of the circuit board adjacent to the first side of the panel; a plurality of LEDs operably connected to the first side of the circuit board; characterized by, a plurality of optical wave guides, each wave guide having a first end and a second end, the first end disposed in one of the bores and the second end optically connected to one of the LEDs the panel has a thickness of from about 15,24 cm (1⁄2') to about 2,54cm (1 "), preferably of about 1,905cm (3⁄4") and the LED, the optical wave guide and the bore are all aligned on an axis that is orthogonal to the first side and the second side of the panel.
A combustion chamber comprising an outer wall and an inner wall spaced from the outer wall, the outer wall having at least one mounting aperture extending there-through, the inner wall having at least one fastener extending there-from, the at least one fastener on the inner wall extending through a corresponding mounting aperture in the outer wall, a cooperating fastener locating on the at least one fastener extending through the corresponding mounting aperture and a washer positioned on the at least one fastener between the outer wall and the cooperating fastener, the washer having a first surface abutting an outer surface of the outer wall and a second surface abutting a surface of the cooperating fastener, the washer having a rim and a bore, the washer having at least one passage extending there-through from the rim to the bore, characterised in that the washer has a sleeve, the sleeve extending into the mounting aperture in the outer wall and the sleeve being arranged around the fastener to guide the flow of coolant around the fastener, and additionally or alternatively, the washer has at least one groove extending from the rim towards the bore on the first surface and/or the washer has at least one groove extending from the bore towards the rim on the second surface and/or the surface of the cooperating fastener abutting the second surface of the washer has at least one groove extending towards the bore of the washer, whereby a flow of coolant is provided to flow through the mounting aperture and around the at least one fastener.
A system for the treatment of food waste in dish washing installations in restaurants, industrial kitchens, wherein there is mounted in a dish-washing sink in a restaurant or industrial kitchen a food waste mill, arranged to mill down food waste together with water, wherein there is connected a pipeline from the food waste mill for waste water from the food waste mill to the inlet of a slurry tank arranged for the separation of sludge from the waste water, whereby the slurry tank is provided with an inlet for the uncleaned waste water at an upper part of the tank, and wherein there is connected from the slurry tank a pipeline to a fat-separation tank for the separation of remaining fat in the waste water from the slurry tank, and wherein there is connected from the fat separator a pipeline for the removal of remaining waste water to a waste-water network, characterized in that the inlet is so designed that the waste water is directed outwards, principally horizontally, towards inner surfaces of the sides of the tank.