A compound of Formula: wherein X is N or CR 6; R 1 is a member selected from the group consisting of: H, -C 1-5 alkyl, -C 1-5 haloalkyl, -C 1-5 alkoxy, -(CH 2) 2 C(=O)OCH 3, -(CH 2) 1-3 OH, -(CH 2) 1-2 O-C 1-5 alkyl, -CH(CH 3)OCH 3, -C(CH 3) 2 OCH 3, -CH 2 SO 2 CH 3, -C(=O)H, -NH-C 1- salkyl, -N(C 1-5 alkyl) 2, -C(=O)N C 1-5 alkyl, -C(=O)N(C 1-5 alkyl) 2, -C 3-8 cycloalkyl,-(CH 2)-C 3-8 cycloalkyl, -CH(CH 3)-C 3-8 cycloalkyl, -NH-C 3-8 cycloalkyl, -C(=O)NH-cyclopropyl,-C(=O)-NH-phenyl, -C(=O)-azetidinyl, -C(=O)-pyrrolidinyl, azetidinyl, phenyl, benzyl, oxetanyl, tetrahydrofuranyl, tetrahydropyranyl, -CH 2 -pyrazinyl, furanyl, thienyl, and pyridinyl, wherein the -C 3-8 cycloalkyl, phenyl, oxetanyl, azetidinyl, tetrahydrofuranyl, tetrahydropyranyl, pyridinyl, pyrazinyl, furanyl and thienyl rings are each independently optionally substituted with 1-3 substituents selected from the group consisting of: halo, -C 1-5 alkyl, -C 1-5 haloalkyl, -C 1-5 haloalkoxy, -OH, and -C(=O)OC 1-5 alkyl; R 2 is selected from the group consisting of: wherein each R 2 is independently optionally substituted with a member selected from the group consisting of: 3 H, halo, -C 1-5 alkyl, -C 1-5 alkenyl, -CN, -OH, CH=CHCH 2 OH, -(CH 2) 3 COH, C(=O)OC 1-5 alkyl, and phenyl; R 3 is selected from the group consisting of: H, halo, -C 1-5 alkyl, -S-C 1-5 alkyl, -C 1-5 haloalkyl,-C 1-5 alkoxy, -NR 3a R 3b, -OH, -(CH 2) 1-3 OH, -CH=CHCH 2 OH, -C 3-8 cycloalkyl, piperidinyl, piperazinyl, morpholinyl, and pyridyl; each R 3a and R 3b are independently selected from the group consisting of H and C 1-5 alkyl; R 4 is selected from the group consisting of: H, halo, -CH 3, and -CF 3; R 5 is selected from the group consisting of: H, -OH, -C 1-5 alkyl, -C 1-5 alkoxy, -C 1-5 haloalkyl,-C 1-5 haloalkoxy, -NR 5a R 5b, azetidinyl, and morpholinyl; each R 5a and R 5b are independently selected from the group consisting of: -C 1-5 alkyl, and -C 1-5 haloalkyl; R 6 is selected from the group consisting of: H, -OH, -CHF 2, and -Br; and R 7 is H or -C 1-5 alkyl; and pharmaceutically acceptable salts, N-oxides, or solvates thereof. X is N or CR 6; R 1 is a member selected from the group consisting of: H, -C 1-5 alkyl, -C 1-5 haloalkyl, -C 1-5 alkoxy, -(CH 2) 2 C(=O)OCH 3, -(CH 2) 1-3 OH, -(CH 2) 1-2 O-C 1-5 alkyl, -CH(CH 3)OCH 3, -C(CH 3) 2 OCH 3, -CH 2 SO 2 CH 3, -C(=O)H, -NH-C 1- salkyl, -N(C 1-5 alkyl) 2, -C(=O)N C 1-5 alkyl, -C(=O)N(C 1-5 alkyl) 2, -C 3-8 cycloalkyl,-(CH 2)-C 3-8 cycloalkyl, -CH(CH 3)-C 3-8 cycloalkyl, -NH-C 3-8 cycloalkyl, -C(=O)NH-cyclopropyl,-C(=O)-NH-phenyl, -C(=O)-azetidinyl, -C(=O)-pyrrolidinyl, azetidinyl, phenyl, benzyl, oxetanyl, tetrahydrofuranyl, tetrahydropyranyl, -CH 2 -pyrazinyl, furanyl, thienyl, and pyridinyl, wherein the -C 3-8 cycloalkyl, phenyl, oxetanyl, azetidinyl, tetrahydrofuranyl, tetrahydropyranyl, pyridinyl, pyrazinyl, furanyl and thienyl rings are each independently optionally substituted with 1-3 substituents selected from the group consisting of: halo, -C 1-5 alkyl, -C 1-5 haloalkyl, -C 1-5 haloalkoxy, -OH, and -C(=O)OC 1-5 alkyl; R 2 is selected from the group consisting of: wherein each R 2 is independently optionally substituted with a member selected from the group consisting of: 3 H, halo, -C 1-5 alkyl, -C 1-5 alkenyl, -CN, -OH, CH=CHCH 2 OH, -(CH 2) 3 COH, C(=O)OC 1-5 alkyl, and phenyl; R 3 is selected from the group consisting of: H, halo, -C 1-5 alkyl, -S-C 1-5 alkyl, -C 1-5 haloalkyl,-C 1-5 alkoxy, -NR 3a R 3b, -OH, -(CH 2) 1-3 OH, -CH=CHCH 2 OH, -C 3-8 cycloalkyl, piperidinyl, piperazinyl, morpholinyl, and pyridyl; each R 3a and R 3b are independently selected from the group consisting of H and C 1-5 alkyl; R 4 is selected from the group consisting of: H, halo, -CH 3, and -CF 3; R 5 is selected from the group consisting of: H, -OH, -C 1-5 alkyl, -C 1-5 alkoxy, -C 1-5 haloalkyl,-C 1-5 haloalkoxy, -NR 5a R 5b, azetidinyl, and morpholinyl; each R 5a and R 5b are independently selected from the group consisting of: -C 1-5 alkyl, and -C 1-5 haloalkyl; R 6 is selected from the group consisting of: H, -OH, -CHF 2, and -Br; and R 7 is H or -C 1-5 alkyl;