mhurhangee/ep-ind-claims huggingface dataset:
A microfluidic system, comprising: a microfluidic device; and a receptacle that receives the microfluidic device during operation, wherein the microfluidic device comprises a first substrate having a first layer, a second layer and a third layer, the substrate defining a microfluidic network comprising a channel and a valve; wherein the valve comprises a mass of thermally responsive substance; wherein the valve has a normally open state in which the valve allows passage of material between an upstream portion of the channel and a downstream portion of the channel, and a closed state in which the mass of thermally responsive substance obstructs passage of material between the upstream portion and the downstream portion of the channel; wherein the valve is configured to thermally contact a heater for raising the temperature of the mass of thermally responsive substance to selectively obstruct or allow the passage of material within the microfluidic network; wherein the heater is incorporated in the receptacle that receives the microfluidic device during operation; wherein the valve comprises a side channel and the mass of thermally responsive substance is present in at least the side channel; and wherein the microfluidic device further comprising a hole and a chamber, and wherein the side channel comprises an end that is connected to the hole and wherein the hole is connected to the chamber. a microfluidic device; and a receptacle that receives the microfluidic device during operation, wherein the microfluidic device comprises a first substrate having a first layer, a second layer and a third layer, the substrate defining a microfluidic network comprising a channel and a valve; wherein the valve comprises a mass of thermally responsive substance; wherein the valve has a normally open state in which the valve allows passage of material between an upstream portion of the channel and a downstream portion of the channel, and a closed state in which the mass of thermally responsive substance obstructs passage of material between the upstream portion and the downstream portion of the channel; wherein the valve is configured to thermally contact a heater for raising the temperature of the mass of thermally responsive substance to selectively obstruct or allow the passage of material within the microfluidic network; wherein the heater is incorporated in the receptacle that receives the microfluidic device during operation; wherein the valve comprises a side channel and the mass of thermally responsive substance is present in at least the side channel; and wherein the microfluidic device further comprising a hole and a chamber, and wherein the side channel comprises an end that is connected to the hole and wherein the hole is connected to the chamber.
An optical fiber connector, comprising: a housing, having a window; a core tube, rotatably disposed in the housing, the core tube having a gear structure, characterised in that a portion of the gear structure is exposed out of the housing through the window; and in that the optical fiber connector further comprises a blocking member, having a gear rack structure, the blocking member being detachably assembled to the window to cover the core tube, the gear rack structure being locked with the gear structure to prevent the core tube from rotation. a housing, having a window; a core tube, rotatably disposed in the housing, the core tube having a gear structure, characterised in that a portion of the gear structure is exposed out of the housing through the window; and in that the optical fiber connector further comprises a blocking member, having a gear rack structure, the blocking member being detachably assembled to the window to cover the core tube, the gear rack structure being locked with the gear structure to prevent the core tube from rotation.
A method for predicting outcome of a Central Nervous System tumor in a patient, comprising: testing the CNS tumor, or cells or nucleic acids shed from the tumor, for the presence of an inactivating mutation in ATRX, wherein the mutation is a positive prognostic indicator. testing the CNS tumor, or cells or nucleic acids shed from the tumor, for the presence of an inactivating mutation in ATRX, wherein the mutation is a positive prognostic indicator.
An instrument for connection to a process flange (102, 104; 202, 204) and to a field circuit in a nuclear installation, comprising: a sensor module that is connectable to the process flange and that includes a support conduit that has support conduit threads and that carries a sensor output lead; an electronic circuit (126; 226) that receives a sensor output from the sensor output lead; a connector (128; 228) that is wired to the electronic circuit and having field circuit contacts including contact pins (162, 164; 262, 264), the connector including a connector shell (168; 268), an electrically insulating and hermetically sealing feedthrough (166; 266) supporting the contact pins within the connector shell, and an alignment key (133; 233) that is aligned with the field circuit contacts of the connector; a thermal and nuclear radiation shield (134; 234) that encloses the electronic circuit (126; 226) and that includes a shock protection annulus (136; 236) that protrudes from a main body (134A; 234A) of the thermal and nuclear radiation shield (134; 234), the connector shell being welded inside the shock protection annulus (136; 236) and sealing the shock protection annulus, and the main body (134A; 234A) including shield threads (137; 237) that rotatably engage the support conduit threads to rotate an alignment of the alignment key (133; 233) relative to the process flange (102, 104; 202, 204). a sensor module that is connectable to the process flange and that includes a support conduit that has support conduit threads and that carries a sensor output lead; an electronic circuit (126; 226) that receives a sensor output from the sensor output lead; a connector (128; 228) that is wired to the electronic circuit and having field circuit contacts including contact pins (162, 164; 262, 264), the connector including a connector shell (168; 268), an electrically insulating and hermetically sealing feedthrough (166; 266) supporting the contact pins within the connector shell, and an alignment key (133; 233) that is aligned with the field circuit contacts of the connector; a thermal and nuclear radiation shield (134; 234) that encloses the electronic circuit (126; 226) and that includes a shock protection annulus (136; 236) that protrudes from a main body (134A; 234A) of the thermal and nuclear radiation shield (134; 234), the connector shell being welded inside the shock protection annulus (136; 236) and sealing the shock protection annulus, and the main body (134A; 234A) including shield threads (137; 237) that rotatably engage the support conduit threads to rotate an alignment of the alignment key (133; 233) relative to the process flange (102, 104; 202, 204).
A welding and cutting device for continuous packaging of food products inserted into a continuous tubular casing advancing along a conveying path, comprising: - a welding and cutting station through which the tubular casing slides; - a welding and cutting member that is movable towards and away from the welding and cutting station so as to weld and cut said tubular casing at predefined welding and cutting zones; - at least one pair of sheets (4, 5) that are movable at least between a wedge position, wherein two corresponding ends (4a, 5a) of said sheets (4,5) are at a minimum distance from one another, and a spread apart position, wherein said two ends (4a, 5a) are at a maximum distance from one another, characterised in that said welding and cutting device comprises a cam rotating around a rotation axis, said cam being operationally active on said sheets (4, 5) to take the sheets (4, 5) from the wedge position to the spread apart position and vice versa. - a welding and cutting station through which the tubular casing slides; - a welding and cutting member that is movable towards and away from the welding and cutting station so as to weld and cut said tubular casing at predefined welding and cutting zones; - at least one pair of sheets (4, 5) that are movable at least between a wedge position, wherein two corresponding ends (4a, 5a) of said sheets (4,5) are at a minimum distance from one another, and a spread apart position, wherein said two ends (4a, 5a) are at a maximum distance from one another,
Composition comprising a. 10 2 to 10 12 cfu of probiotic bacteria per gram uronic acid oligosaccharide, wherein the probiotic bacteria are selected from Lactobacillus and/or Bifidobacterium; and b. 25 to 100 wt.% uronic acid oligosaccharide with a DP of 2 to 250 based on total weight of uronic acid in the composition, wherein the uronic acid oligosaccharide is obtainable by enzymatic digestion of pectin with pectin lyase and/or pectic lyase. a. 10 2 to 10 12 cfu of probiotic bacteria per gram uronic acid oligosaccharide, wherein the probiotic bacteria are selected from Lactobacillus and/or Bifidobacterium; and b. 25 to 100 wt.% uronic acid oligosaccharide with a DP of 2 to 250 based on total weight of uronic acid in the composition,
Method for displaying information arranged in lists on a display surface, in which - the information is presented in an operating state and in a display state, in which case an operating process can be carried out by means of an input device in the operating state and an operating process cannot be carried out by means of the input device in the display state, - a subset of a list comprising a plurality of list entries is displayed on the display surface, the list entries each occupying a region of the display surface, - the displayed subset of the list is changed in the operating state by means of a first operating process by a user, in which case the area occupied by a list entry on the display surface does not change, characterized in that - if a list entry has been selected in the operating state by means of a second operating process by a user, the selected list entry is moved into the foreground in the display state and the remaining list entries in the list are moved into the background by being perspectively presented in a manner pivoted to the rear. - the information is presented in an operating state and in a display state, in which case an operating process can be carried out by means of an input device in the operating state and an operating process cannot be carried out by means of the input device in the display state, - a subset of a list comprising a plurality of list entries is displayed on the display surface, the list entries each occupying a region of the display surface, - the displayed subset of the list is changed in the operating state by means of a first operating process by a user, in which case the area occupied by a list entry on the display surface does not change, characterized in that - if a list entry has been selected in the operating state by means of a second operating process by a user, the selected list entry is moved into the foreground in the display state and the remaining list entries in the list are moved into the background by being perspectively presented in a manner pivoted to the rear.
A chair comprising a base, a transom supported on the base, a seat portion and a back portion supported on the transom, and a rocking mechanism configured to enable the transom to rock forward and rearward relative to the base; the rocking mechanism comprising: a concave rock surface (21, 1021a, 1021b, 1021c) provided on the base; a convex rock surface (18, 1018a, 1018b, 1018c) operatively provided on the transom and arranged to be in rolling contact with the concave rock surface (21, 1021a, 1021b, 1021c), the convex rock surface (18, 1018a, 1018b, 1018c) having a radius of curvature less than a radius of curvature of the concave rock surface (21, 1021a, 1021b, 1021c); and complementary engagement features operatively provided on the transom and on the base; characterized in that the engagement features comprise a gear (23, 1023a, 1023b) with a plurality of teeth on the transom and a curved array of recesses and/or teeth (25, 1025a, 1025b) on the base, wherein the gear (23, 1023a, 1023b) is in rolling contact with the curved array of recesses and/or teeth (25, 1025a, 1025b) on the base, wherein at least one of the teeth of the gear (23, 1023a, 1023b) is seated in a complementary recess and/or between the teeth of the curved array (25, 1025a, 1025b) when the transom is in a neutral position, and configured such that rocking the transom forward or rearwards moves the at least one of the teeth away from its seated position. a concave rock surface (21, 1021a, 1021b, 1021c) provided on the base; a convex rock surface (18, 1018a, 1018b, 1018c) operatively provided on the transom and arranged to be in rolling contact with the concave rock surface (21, 1021a, 1021b, 1021c), the convex rock surface (18, 1018a, 1018b, 1018c) having a radius of curvature less than a radius of curvature of the concave rock surface (21, 1021a, 1021b, 1021c); and complementary engagement features operatively provided on the transom and on the base; characterized in that the engagement features comprise a gear (23, 1023a, 1023b) with a plurality of teeth on the transom and a curved array of recesses and/or teeth (25, 1025a, 1025b) on the base, wherein the gear (23, 1023a, 1023b) is in rolling contact with the curved array of recesses and/or teeth (25, 1025a, 1025b) on the base, wherein at least one of the teeth of the gear (23, 1023a, 1023b) is seated in a complementary recess and/or between the teeth of the curved array (25, 1025a, 1025b) when the transom is in a neutral position, and configured such that rocking the transom forward or rearwards moves the at least one of the teeth away from its seated position.
A compound of Formula: or a pharmaceutically acceptable salt thereof; wherein R is a member selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, halogen selected from F, Cl, Br and I, alkoxy containing 1 to 3 carbon atoms, nitro, hydroxy, trifluoromethyl, and thioalkoxy containing 1 to 3 carbon atoms; x is an integer of 0 to 3, with the proviso that R may be the same or different when x is 2 or 3; R 1 and R 2 are independently selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, aryl, arylalkyl, cycloalkyl of 3 to 7 carbon atoms; or R 1 and R 2 can be joined to form a 5 to 7-membered heterocycle substituted with a member selected from the group consisting of hydrogen, alkyl, and aryl groups, wherein the heterocycle can comprise 1 to 2 nitrogen atoms and 0 to 1 oxygen atom, wherein the nitrogen atoms are not directly connected with each other or with the oxygen atom; for use in a method for treating cataplexy associated with narcolepsy in a subject in need thereof, wherein the subject has 3 or more cataplectic events per week when untreated. wherein R is a member selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, halogen selected from F, Cl, Br and I, alkoxy containing 1 to 3 carbon atoms, nitro, hydroxy, trifluoromethyl, and thioalkoxy containing 1 to 3 carbon atoms; x is an integer of 0 to 3, with the proviso that R may be the same or different when x is 2 or 3; R 1 and R 2 are independently selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, aryl, arylalkyl, cycloalkyl of 3 to 7 carbon atoms; or R 1 and R 2 can be joined to form a 5 to 7-membered heterocycle substituted with a member selected from the group consisting of hydrogen, alkyl, and aryl groups, wherein the heterocycle can comprise 1 to 2 nitrogen atoms and 0 to 1 oxygen atom, wherein the nitrogen atoms are not directly connected with each other or with the oxygen atom; for use in a method for treating cataplexy associated with narcolepsy in a subject in need thereof, wherein the subject has 3 or more cataplectic events per week when untreated.
Rock drilling machine comprising a piston that is arranged to move back and forth in a pressure chamber (12a, 12b) when the rock drilling machine is in use, a cavitation-sensitive component, and an oil channel that is arranged to extend between the pressure chamber (12a, 12b) and said cavitation-sensitive component, characterized in that said oil channel comprises a series of restrictions and oil volumes, to hinder the spreading of cavitation bubbles through said oil channel, wherein movement of oil from said oil volumes, which are hydraulically connected to said pressure chamber (12a, 12b), is hindered when a pressure decrease occurs in said pressure chamber (12a, 12b).
A method for making available a communication, with a plurality of communication subscribers (TA, T1...TN), with at least one first piece of address information associated with a first communication subscriber in a first communication network, with a second piece of address information associated with at least one second communication subscriber in the first communication network, and with at least one third piece of address information (R1a) which is associated with the at least one second communication subscriber in a second communication network which is connected to the first communication network via a trunk line and via at least one connection control, as well as with a forth piece of address information associated with a central control function in the first communication network, characterized in that upon a failure of a first connection attempt to the second communication subscriber within the first communication network, which attempt was initiated by a communication subscriber determined by the first piece of address information using the second piece of address information, upon a second connection attempt, following the failure, by the first communication subscriber determined by the first piece of address information to the central control function, determined by the fourth piece of address information, in the first communication network the first piece of address information is detected and a check is made whether a piece of association information for the second piece of address information belonging to the first, failed connection attempt is stored, and the control function automatically initiates a forwarding of the second connection to the second communication subscriber using the third piece of address information (R1a) to the second communication network.
A safety arrangement (23, 45, 51) for a vehicle, said safety arrangement (23, 45, 51) comprising a bonnet (25, 25', 25") and at least one support member (41, 53), whereby in case of a collision between said vehicle and a large animal with the centre of gravity of its body at a height adjacent to or above the height at a front end of said vehicle, said bonnet (25, 25', 25") is supported from beneath by said at least one support member (41, 53) in at least a rear central portion, such that a rear portion of said bonnet (25, 25', 25") is adapted to be raised from a closed position to a ramp position to form a ramp for said large animal, said bonnet (25, 25', 25"), when forming said ramp, has an angle (α) of between 5° and 60° to a horizontal plane of said vehicle, said ramp being adapted to direct said large animal over a windscreen and/or a roof structure of said vehicle, and said ramp being inclined to minimize the risk of injury for a person located in a passenger compartment of said vehicle and/or minimizing the damages to said vehicle characterized in that said bonnet (25, 25', 25"), when forming said ramp substantially covers an engine compartment of said vehicle.
Method for the rapid transportation of products (13, 14) at a 90° diversion from a first transportation unit to a second transportation unit towards a packing machine, characterised in that after loading onto the second transportation unit, the products (13, 14) are brought up with variable acceleration to the transfer speed by means of a servo-propelled slider (8, 9), depending on the product and situation.
A continuous casting method of steel, the method comprising the steps of: bulging wide side surfaces of a slab having thereinside an unsolidified layer with a total intentional bulging amount of 3 to 10 mm by increasing stepwise toward a downstream side in a casting direction a roller gap of a plurality of pairs of slab support rollers disposed in a curved type continuous casting machine or a vertical-bending type continuous casting machine; and after the bulging of the wide side surfaces of the slab, performing rolling reduction on the wide side surfaces of the slab in a soft reduction zone in which the roller gap of a plurality of pairs of slab support rollers is reduced stepwise toward the downstream side in the casting direction; wherein the wide side surfaces of the slab undergo rolling reduction at a rolling reduction speed of 0.3 to 2.0 mm/min with a total rolling reduction amount smaller than or equal to the total intentional bulging amount in the soft reduction zone, such that a solid phase fraction at a center of a thickness of the slab is smaller than 0.2 in a reformation zone in which a shape of the slab in the casting direction is reformed from a circular arc shape into a linear shape, and wherein a start point of the rolling reduction in the soft reduction zone is a position out of the reformation zone and downstream of the reformation zone in the casting direction. bulging wide side surfaces of a slab having thereinside an unsolidified layer with a total intentional bulging amount of 3 to 10 mm by increasing stepwise toward a downstream side in a casting direction a roller gap of a plurality of pairs of slab support rollers disposed in a curved type continuous casting machine or a vertical-bending type continuous casting machine; and after the bulging of the wide side surfaces of the slab, performing rolling reduction on the wide side surfaces of the slab in a soft reduction zone in which the roller gap of a plurality of pairs of slab support rollers is reduced stepwise toward the downstream side in the casting direction; wherein the wide side surfaces of the slab undergo rolling reduction at a rolling reduction speed of 0.3 to 2.0 mm/min with a total rolling reduction amount smaller than or equal to the total intentional bulging amount in the soft reduction zone, such that a solid phase fraction at a center of a thickness of the slab is smaller than 0.2 in a reformation zone in which a shape of the slab in the casting direction is reformed from a circular arc shape into a linear shape, and wherein a start point of the rolling reduction in the soft reduction zone is a position out of the reformation zone and downstream of the reformation zone in the casting direction.