A tissue closure device, comprising: a first clamping base and a second clamping base which may be opened and closed oppositely and form a cavity therebetween for accommodating a tubular tissue when being closed; and a pouch assembly arranged to cooperate with the first clamping base and the second clamping base, wherein the pouch assembly comprises: a tying band which extends along a side, facing the cavity, of each of the first clamping base and the second clamping base, and is provided with a first free end located at the distal end of the first clamping base and a second free end located at the distal end of the second clamping base; characterized in that it further comprises: a first tying band buckle which is slidably arranged on the tying band in a penetrating manner and arranged adjacent to the first free end in an initial state; a second tying band buckle which is slidably arranged on the tying band in a penetrating manner and arranged adjacent to the second free end in an initial state, wherein the second tying band buckle is opposite to the first tying band buckle and buckled with the first tying band buckle after the tubular tissue is accommodated in the cavity and the first clamping base and the second clamping base are closed; and a first driving mechanism which enables the first tying band buckle and the second tying band buckle to move synchronously relative to the tying band after the first tying band buckle and the second tying band buckle are buckled and then cooperate with the tying band to gather the tubular tissue into a further pouch. a first clamping base and a second clamping base which may be opened and closed oppositely and form a cavity therebetween for accommodating a tubular tissue when being closed; and a pouch assembly arranged to cooperate with the first clamping base and the second clamping base, wherein the pouch assembly comprises: a tying band which extends along a side, facing the cavity, of each of the first clamping base and the second clamping base, and is provided with a first free end located at the distal end of the first clamping base and a second free end located at the distal end of the second clamping base; characterized in that it further comprises: a first tying band buckle which is slidably arranged on the tying band in a penetrating manner and arranged adjacent to the first free end in an initial state; a second tying band buckle which is slidably arranged on the tying band in a penetrating manner and arranged adjacent to the second free end in an initial state, wherein the second tying band buckle is opposite to the first tying band buckle and buckled with the first tying band buckle after the tubular tissue is accommodated in the cavity and the first clamping base and the second clamping base are closed; and a first driving mechanism which enables the first tying band buckle and the second tying band buckle to move synchronously relative to the tying band after the first tying band buckle and the second tying band buckle are buckled and then cooperate with the tying band to gather the tubular tissue into a further pouch. a tying band which extends along a side, facing the cavity, of each of the first clamping base and the second clamping base, and is provided with a first free end located at the distal end of the first clamping base and a second free end located at the distal end of the second clamping base; characterized in that it further comprises: a first tying band buckle which is slidably arranged on the tying band in a penetrating manner and arranged adjacent to the first free end in an initial state; a second tying band buckle which is slidably arranged on the tying band in a penetrating manner and arranged adjacent to the second free end in an initial state, wherein the second tying band buckle is opposite to the first tying band buckle and buckled with the first tying band buckle after the tubular tissue is accommodated in the cavity and the first clamping base and the second clamping base are closed; and a first driving mechanism which enables the first tying band buckle and the second tying band buckle to move synchronously relative to the tying band after the first tying band buckle and the second tying band buckle are buckled and then cooperate with the tying band to gather the tubular tissue into a further pouch. a first tying band buckle which is slidably arranged on the tying band in a penetrating manner and arranged adjacent to the first free end in an initial state; a second tying band buckle which is slidably arranged on the tying band in a penetrating manner and arranged adjacent to the second free end in an initial state, wherein the second tying band buckle is opposite to the first tying band buckle and buckled with the first tying band buckle after the tubular tissue is accommodated in the cavity and the first clamping base and the second clamping base are closed; and a first driving mechanism which enables the first tying band buckle and the second tying band buckle to move synchronously relative to the tying band after the first tying band buckle and the second tying band buckle are buckled and then cooperate with the tying band to gather the tubular tissue into a further pouch.