A vehicle-body structure of a vehicle, comprising: a vehicle-body frame member forming an opening portion for entrance at a vehicle side part; and a side door provided so as to open and/or close the opening portion, wherein the side door comprises a door panel portion and a reinforcement portion (71 to 74) provided at a peripheral part of the door panel portion such that the reinforcement portion (71 to 74) overlaps with the vehicle-body frame member in a vehicle side view, the reinforcement portion (71 to 74) being a plate member, wherein the vehicle-body frame member comprises a side sill, a hinge pillar, a center pillar, and a roof side rail, and the peripheral part of the door panel portion comprises plural overlapping portions (63, 64, 65, 67) which respectively overlap with the side sill, the hinge pillar, the center pillar, and the roof side rail in the vehicle side view, characterized in that the reinforcement portion (71 to 74) comprises a lower-side reinforcement portion attached to the overlapping portion which overlaps with the side sill, a front-side reinforcement portion attached to the overlapping portion which overlaps with the hinge pillar, a rear-side reinforcement portion attached to the overlapping portion which overlaps with the center pillar, and an upper-side reinforcement portion attached to the overlapping portion which overlaps with the roof side rail, a side-sill reinforcement (14, 15) is provided inside the side sill, a hinge-pillar reinforcement is provided inside the hinge pillar, a center-pillar reinforcement is provided inside the center pillar, and a roof-side reinforcement is provided inside the roof side rail. a vehicle-body frame member forming an opening portion for entrance at a vehicle side part; and a side door provided so as to open and/or close the opening portion, wherein the side door comprises a door panel portion and a reinforcement portion (71 to 74) provided at a peripheral part of the door panel portion such that the reinforcement portion (71 to 74) overlaps with the vehicle-body frame member in a vehicle side view, the reinforcement portion (71 to 74) being a plate member, wherein the vehicle-body frame member comprises a side sill, a hinge pillar, a center pillar, and a roof side rail, and the peripheral part of the door panel portion comprises plural overlapping portions (63, 64, 65, 67) which respectively overlap with the side sill, the hinge pillar, the center pillar, and the roof side rail in the vehicle side view, characterized in that the reinforcement portion (71 to 74) comprises a lower-side reinforcement portion attached to the overlapping portion which overlaps with the side sill, a front-side reinforcement portion attached to the overlapping portion which overlaps with the hinge pillar, a rear-side reinforcement portion attached to the overlapping portion which overlaps with the center pillar, and an upper-side reinforcement portion attached to the overlapping portion which overlaps with the roof side rail, a side-sill reinforcement (14, 15) is provided inside the side sill, a hinge-pillar reinforcement is provided inside the hinge pillar, a center-pillar reinforcement is provided inside the center pillar, and a roof-side reinforcement is provided inside the roof side rail.