A luer connector comprising: a rigid housing, a first end comprising a rigid tubular male portion configured to be engageable with a female connector and positioned at a first end of the housing, a second end comprising a rigid tubular female member and positioned at a second end of the housing; wherein: the female member is configured to define at least a first arrangement wherein the female member is configured to allow a male connector to rotate substantially unimpeded in either a first direction or a second direction relative to the female member, the first direction being defined as the direction that permits the male connector to threadably engage the female member, and the second direction being defined as the direction that permits the male connector to threadably disengage the female member, and a second arrangement wherein the female member is configured to prevent or impede the male connector from rotating in the first direction or the second direction relative to the female member; the female member is further configured to change from the first arrangement to the second arrangement when the male connector is further rotated in the first direction beyond a point at which the male connector is fully engaged with the female member; the female member comprises a first member defining a first cylindrical surface including at least one engaging surface and a second member defining a second cylindrical surface including at least one engaging surface; the first cylindrical surface is generally co-axially aligned with and adjacent to the second cylindrical surface; the first member is supported by the housing so as to be prevented from rotating relative to the housing; the second member being supported by the first member and configured so as to be threadably engageable by a male connector; the engaging surface of the second member is configured to interact with the engaging surface of the first member so as to prevent the second member from rotating relative to the first member; and either the engaging surface of the second member or the engaging surface of the first member being configured to break away when a predetermined amount of manual torque is applied to the second member relative to the first member, thereby allowing the second member to rotate freely relative to the first member. the female member is configured to define at least a first arrangement wherein the female member is configured to allow a male connector to rotate substantially unimpeded in either a first direction or a second direction relative to the female member, the first direction being defined as the direction that permits the male connector to threadably engage the female member, and the second direction being defined as the direction that permits the male connector to threadably disengage the female member, and a second arrangement wherein the female member is configured to prevent or impede the male connector from rotating in the first direction or the second direction relative to the female member; the female member is further configured to change from the first arrangement to the second arrangement when the male connector is further rotated in the first direction beyond a point at which the male connector is fully engaged with the female member; the female member comprises a first member defining a first cylindrical surface including at least one engaging surface and a second member defining a second cylindrical surface including at least one engaging surface; the first cylindrical surface is generally co-axially aligned with and adjacent to the second cylindrical surface; the first member is supported by the housing so as to be prevented from rotating relative to the housing; the second member being supported by the first member and configured so as to be threadably engageable by a male connector; the engaging surface of the second member is configured to interact with the engaging surface of the first member so as to prevent the second member from rotating relative to the first member; and either the engaging surface of the second member or the engaging surface of the first member being configured to break away when a predetermined amount of manual torque is applied to the second member relative to the first member, thereby allowing the second member to rotate freely relative to the first member.