A prosthetic mitral valve and deployment system, comprising: a prosthetic mitral valve system comprising: a prosthetic anchor assembly comprising an anchor frame, the anchor frame defining an interior space; and a prosthetic valve assembly (17, 400) comprising a valve frame and multiple valve leaflets attached to the valve frame, wherein the valve frame is configured to releasably couple with the prosthetic anchor assembly within the interior space; a system of multiple catheters (120, 140, 150, 160) configured to deliver the prosthetic mitral valve system, wherein at least some catheters of the multiple catheters are slidably engageable with each other, wherein at least a first catheter of the multiple catheters is releasably coupleable to the prosthetic anchor assembly, wherein at least a second catheter of the multiple catheters is releasably coupleable to the prosthetic valve assembly; and a deployment frame system (6, 500, 700, 900, 1100, 1300, 1500, 1700) comprising: a plurality of clamps (543, 552, 561, 562, 563, 571, 572, 573, 575, 1523, 1533, 1543), each clamp of the plurality of clamps configured to releasably clamp a proximal end portion of a respective catheter of the multiple catheters; a first frame (510, 710, 910, 1110 1310, 1510, 520, 720, 1120, 1320, 1520), wherein each clamp of the plurality of clamps is configured to releasably couple with the first frame; and a second frame (510, 710, 910, 1110 1310, 1510, 520, 720, 1120, 1320, 1520), wherein at least one clamp of the plurality of clamps is configured to releasably couple with the second frame. a prosthetic mitral valve system comprising: a prosthetic anchor assembly comprising an anchor frame, the anchor frame defining an interior space; and a prosthetic valve assembly (17, 400) comprising a valve frame and multiple valve leaflets attached to the valve frame, wherein the valve frame is configured to releasably couple with the prosthetic anchor assembly within the interior space; a prosthetic anchor assembly comprising an anchor frame, the anchor frame defining an interior space; and a prosthetic valve assembly (17, 400) comprising a valve frame and multiple valve leaflets attached to the valve frame, wherein the valve frame is configured to releasably couple with the prosthetic anchor assembly within the interior space; a system of multiple catheters (120, 140, 150, 160) configured to deliver the prosthetic mitral valve system, wherein at least some catheters of the multiple catheters are slidably engageable with each other, wherein at least a first catheter of the multiple catheters is releasably coupleable to the prosthetic anchor assembly, wherein at least a second catheter of the multiple catheters is releasably coupleable to the prosthetic valve assembly; and a deployment frame system (6, 500, 700, 900, 1100, 1300, 1500, 1700) comprising: a plurality of clamps (543, 552, 561, 562, 563, 571, 572, 573, 575, 1523, 1533, 1543), each clamp of the plurality of clamps configured to releasably clamp a proximal end portion of a respective catheter of the multiple catheters; a first frame (510, 710, 910, 1110 1310, 1510, 520, 720, 1120, 1320, 1520), wherein each clamp of the plurality of clamps is configured to releasably couple with the first frame; and a second frame (510, 710, 910, 1110 1310, 1510, 520, 720, 1120, 1320, 1520), wherein at least one clamp of the plurality of clamps is configured to releasably couple with the second frame. a plurality of clamps (543, 552, 561, 562, 563, 571, 572, 573, 575, 1523, 1533, 1543), each clamp of the plurality of clamps configured to releasably clamp a proximal end portion of a respective catheter of the multiple catheters; a first frame (510, 710, 910, 1110 1310, 1510, 520, 720, 1120, 1320, 1520), wherein each clamp of the plurality of clamps is configured to releasably couple with the first frame; and a second frame (510, 710, 910, 1110 1310, 1510, 520, 720, 1120, 1320, 1520), wherein at least one clamp of the plurality of clamps is configured to releasably couple with the second frame.