A surgical instrument, comprising: an elongate shaft assembly defining a shaft axis (SA-SA) and comprising a distal end; a surgical end effector comprising a proximal end that is pivotally coupled to said distal end of said elongate shaft assembly for selective pivotal travel relative thereto about an articulation axis (B-B) that is laterally offset from said shaft axis and extends transversely relative thereto; and an articulation system, comprising: an end effector driver link operably coupled to said surgical end effector; an articulation driver supported for longitudinal travel in distal and proximal directions upon application of articulation motions thereto, said articulation driver coupled to said end effector driver link to selectively articulate said surgical end effector relative to said elongate shaft assembly about said articulation axis; and a flexible de-articulation member coupled to said elongate shaft assembly and said surgical end effector to apply de-articulation motions to said surgical end effector, wherein said surgical end effector comprises a firing member that is configured for axial travel within said surgical end effector and wherein said elongate shaft assembly further comprises an axially movable firing beam operably interfacing with said firing member and being selectively movable in said distal direction in response to a firing motion applied thereto, said firing beam being selectively movable in said proximal direction in response to a retraction motion applied thereto. an elongate shaft assembly defining a shaft axis (SA-SA) and comprising a distal end; a surgical end effector comprising a proximal end that is pivotally coupled to said distal end of said elongate shaft assembly for selective pivotal travel relative thereto about an articulation axis (B-B) that is laterally offset from said shaft axis and extends transversely relative thereto; and an articulation system, comprising: an end effector driver link operably coupled to said surgical end effector; an articulation driver supported for longitudinal travel in distal and proximal directions upon application of articulation motions thereto, said articulation driver coupled to said end effector driver link to selectively articulate said surgical end effector relative to said elongate shaft assembly about said articulation axis; and a flexible de-articulation member coupled to said elongate shaft assembly and said an end effector driver link operably coupled to said surgical end effector; an articulation driver supported for longitudinal travel in distal and proximal directions upon application of articulation motions thereto, said articulation driver coupled to said end effector driver link to selectively articulate said surgical end effector relative to said elongate shaft assembly about said articulation axis; and a flexible de-articulation member coupled to said elongate shaft assembly and said surgical end effector to apply de-articulation motions to said surgical end effector, wherein said surgical end effector comprises a firing member that is configured for axial travel within said surgical end effector and wherein said elongate shaft assembly further comprises an axially movable firing beam operably interfacing with said firing member and being selectively movable in said distal direction in response to a firing motion applied thereto, said firing beam being selectively movable in said proximal direction in response to a retraction motion applied thereto.