A slicing and printing method for manufacturing a color 3D model, the method comprising the following steps: a) diving data corresponding to a color 3D object into data corresponding to a coloring model and data corresponding to an interior model (22, 60, 82) according to a coloring thickness, a number of color cells and a size of each of the color cell at a computer device, such that if the coloring thickness is thicker, the number of color cells is more or the size of the color cells is smaller, then the manufactured color appearances of the color 3D model are finer; b) dividing the data corresponding to the coloring model into a plurality of data corresponding to color cells (200, 30, 32, 34, 36, 38), wherein a shell of each of the color cells (200, 30, 32, 34, 36, 38) forms an accommodating space configured to accommodate a color material; c) setting respectively colors of color materials accommodated in each of the color cells (200, 30, 32, 34, 36, 38) according to the color of the data corresponding to the color 3D object, and generating a printing color data corresponding to the color 3D model; and d) generating a printing object data associated with the printing color data according to the printing color data, the data corresponding to the interior model (22, 60, 82) and the data corresponding to the color cells (200, 30, 32, 34, 36, 38); e) controlling a first nozzle to print the color cells (200, 30, 32, 34, 36, 38) layer by layer according to the printing object data at a color 3D printer; and f) during a period of printing the color cells (200, 30, 32, 34, 36, 38), controlling a second nozzle to fill the color materials respectively in the accommodating space of the printed color cells (200, 30, 32, 34, 36, 38) on the same layer according to the printing color data if printing of the color cells (200, 30, 32, 34, 36, 38) on the same layer is complete. a) diving data corresponding to a color 3D object into data corresponding to a coloring model and data corresponding to an interior model (22, 60, 82) according to a coloring thickness, a number of color cells and a size of each of the color cell at a computer device, such that if the coloring thickness is thicker, the number of color cells is more or the size of the color cells is smaller, then the manufactured color appearances of the color 3D model are finer; b) dividing the data corresponding to the coloring model into a plurality of data corresponding to color cells (200, 30, 32, 34, 36, 38), wherein a shell of each of the color cells (200, 30, 32, 34, 36, 38) forms an accommodating space configured to accommodate a color material; c) setting respectively colors of color materials accommodated in each of the color cells (200, 30, 32, 34, 36, 38) according to the color of the data corresponding to the color 3D object, and generating a printing color data corresponding to the color 3D model; and d) generating a printing object data associated with the printing color data according to the printing color data, the data corresponding to the interior model (22, 60, 82) and the data corresponding to the color cells (200, 30, 32, 34, 36, 38); e) controlling a first nozzle to print the color cells (200, 30, 32, 34, 36, 38) layer by layer according to the printing object data at a color 3D printer; and f) during a period of printing the color cells (200, 30, 32, 34, 36, 38), controlling a second nozzle to fill the color materials respectively in the accommodating space of the printed color cells (200, 30, 32, 34, 36, 38) on the same layer according to the printing color data if printing of the color cells (200, 30, 32, 34, 36, 38) on the same layer is complete.