A physiological data acquisition system comprising: at least one interface module, wherein each interface module comprises: a dock configured to mate with two or more different personality modules, the dock including a multi-modal connection port configured to directly connect to a dock connector of any one of the two or more different personality modules so as to receive physiological signals therefrom; a first one of the two or more different personality modules including: a first catheter connector configured to receive a connection end of a first catheter of a first catheter type so as to receive physiological signals therefrom; a first dock connector configured to connect to the multi-modal connection port of the dock so as to provide the physiological signals thereto; a second one of the two or more different personality modules including: a second catheter connector configured to receive a connection end of a second catheter of a second catheter type that is different to the first catheter type so as to receive physiological signals therefrom; a second dock connector configured to connect to the multi-modal connection port of the dock so as to provide the physiological signals thereto; and a base unit configured to communicatively connect to the at least one interface module to receive the physiological signals therefrom, wherein the first personality module comprises: a personality module housing; wherein the first catheter connector is provided on the personality module housing; wherein the first dock connector is provided on the personality module housing; and wherein the personality module housing is configured to engage a dock housing of the dock so as to removably mate with the dock to form one of the at least one interface module. at least one interface module, wherein each interface module comprises: a dock configured to mate with two or more different personality modules, the dock including a multi-modal connection port configured to directly connect to a dock connector of any one of the two or more different personality modules so as to receive physiological signals therefrom; a first one of the two or more different personality modules including: a first catheter connector configured to receive a connection end of a first catheter of a first catheter type so as to receive physiological signals therefrom; a first dock connector configured to connect to the multi-modal connection port of the dock so as to provide the physiological signals thereto; a second one of the two or more different personality modules including: a second catheter connector configured to receive a connection end of a second catheter of a second catheter type that is different to the first catheter type so as to receive physiological signals therefrom; a second dock connector configured to connect to the multi-modal connection port of the dock so as to provide the physiological signals thereto; and a base unit configured to communicatively connect to the at least one interface module to receive the physiological signals therefrom, wherein the first personality module comprises: a dock configured to mate with two or more different personality modules, the dock including a multi-modal connection port configured to directly connect to a dock connector of any one of the two or more different personality modules so as to receive physiological signals therefrom; a first one of the two or more different personality modules including: a first catheter connector configured to receive a connection end of a first catheter of a first catheter type so as to receive physiological signals therefrom; a first dock connector configured to connect to the multi-modal connection port of the dock so as to provide the physiological signals thereto; a first catheter connector configured to receive a connection end of a first catheter of a first catheter type so as to receive physiological signals therefrom; a first dock connector configured to connect to the multi-modal connection port of the dock so as to provide the physiological signals thereto; a second one of the two or more different personality modules including: a second catheter connector configured to receive a connection end of a second catheter of a second catheter type that is different to the first catheter type so as to receive physiological signals therefrom; a second dock connector configured to connect to the multi-modal connection port of the dock so as to provide the physiological signals thereto; and a second catheter connector configured to receive a connection end of a second catheter of a second catheter type that is different to the first catheter type so as to receive physiological signals therefrom; a second dock connector configured to connect to the multi-modal connection port of the dock so as to provide the physiological signals thereto; and a base unit configured to communicatively connect to the at least one interface module to receive the physiological signals therefrom, wherein the first personality module comprises: a personality module housing; wherein the first catheter connector is provided on the personality module housing; wherein the first dock connector is provided on the personality module housing; and wherein the personality module housing is configured to engage a dock housing of the dock so as to removably mate with the dock to form one of the at least one interface module.