Method of separating hybrid wheat seeds from a mixture comprising said hybrid wheat seeds and inbred wheat seeds, comprising (a) providing a mixture of wheat seeds, wherein said mixture of seeds has been obtained by interplanting a combination of plants comprising a male sterile or conditionally male sterile seed parent and a male fertile pollen parent, wherein said seed parent and pollen parent produce at least two types of seeds, at least one of which being said hybrid seeds, said at least two types of seed having different phenotypes allowing separation of said hybrid seed with non-invasive methods based on the differences in said phenotypes, said different phenotypes being determined by an allele or a combination of alleles at one or more genetic loci, wherein said allele or combination of alleles at one or more genetic loci are selected from alleles of the Q, Tg or Sog gene, wherein said seed parent is homozygous for a first allele or combination of alleles at said one or more genetic loci resulting in a first phenotype and said pollen parent is homozygous for a second allele or combination of alleles at said one or more genetic loci resulting in a second phenotype; wherein said seed parent is homozygous for one or a combination of alleles at one or more genetic loci, wherein at least one of said alleles in said seed parent is dominant or partially dominant, and said pollen parent is homozygous for one or a combination of alleles at said one or more genetic loci, wherein at least one of said alleles in said pollen parent is recessive or partially recessive; and wherein said combination of plants is characterized in that (i) said one allele or combination of alleles at one or more genetic loci in said seed parent manifests in seeds with a free-threshing phenotype and wherein said one allele or combination of alleles at one or more genetic loci in said pollen parent manifests in seeds with a hulled phenotype; or (ii) said one allele or combination of alleles at one or more genetic loci in said seed parent manifests in seed with a hulled phenotype and wherein said one allele or combination of alleles at one or more genetic loci in said pollen parent manifests in seeds with a free-threshing phenotype; (b) separating said hybrid seeds using a separation method based on differences in size or specific weight of grains. (a) providing a mixture of wheat seeds, wherein said mixture of seeds has been obtained by interplanting a combination of plants comprising a male sterile or conditionally male sterile seed parent and a male fertile pollen parent, wherein said seed parent and pollen parent produce at least two types of seeds, at least one of which being said hybrid seeds, said at least two types of seed having different phenotypes allowing separation of said hybrid seed with non-invasive methods based on the differences in said phenotypes, said different phenotypes being determined by an allele or a combination of alleles at one or more genetic loci, wherein said allele or combination of alleles at one or more genetic loci are selected from alleles of the Q, Tg or Sog gene, wherein said seed parent is homozygous for a first allele or combination of alleles at said one or more genetic loci resulting in a first phenotype and said pollen parent is homozygous for a second allele or combination of alleles at said one or more genetic loci resulting in a second phenotype; wherein said seed parent is homozygous for one or a combination of alleles at one or more genetic loci, wherein at least one of said alleles in said seed parent is dominant or partially dominant, and said pollen parent is homozygous for one or a combination of alleles at said one or more genetic loci, wherein at least one of said alleles in said pollen parent is recessive or partially recessive; and wherein said combination of plants is characterized in that (i) said one allele or combination of alleles at one or more genetic loci in said seed parent manifests in seeds with a free-threshing phenotype and wherein said one allele or combination of alleles at one or more genetic loci in said pollen parent manifests in seeds with a hulled phenotype; or (ii) said one allele or combination of alleles at one or more genetic loci in said seed parent manifests in seed with a hulled phenotype and wherein said one allele or combination of alleles at one or more genetic loci in said pollen parent manifests in seeds with a free-threshing phenotype; (i) said one allele or combination of alleles at one or more genetic loci in said seed parent manifests in seeds with a free-threshing phenotype and wherein said one allele or combination of alleles at one or more genetic loci in said pollen parent manifests in seeds with a hulled phenotype; or (ii) said one allele or combination of alleles at one or more genetic loci in said seed parent manifests in seed with a hulled phenotype and wherein said one allele or combination of alleles at one or more genetic loci in said pollen parent manifests in seeds with a free-threshing phenotype; (b) separating said hybrid seeds using a separation method based on differences in size or specific weight of grains.