A computer implemented system to digitally quantify alignment and placement parameters in a musculoskeletal application, the computer implemented system comprising: a computer system, coupled to an x-ray emitter and an x-ray detector, wherein said x-ray detector is aligned to said x-ray emitter to capture an image of a patient; said computer system further comprising: i. an image capturing module configured to capture an operative image of a portion of said patient's body; and obtain a reference image of a contra lateral side of said portion of said patient's body; ii. a calibration and anatomical matching module coupled to said image capturing module and configured to 1. calibrate said reference image and said operative image to same magnification; 2. identify at least one first anatomic marker in said reference image and at least one corresponding second anatomic marker in said operative image; and 3. aligning said at least one second anatomic marker with said at least one first anatomic marker on an overlaid image; iii. a differential mapping module coupled to said calibration and anatomical matching module and configured to digitally quantify alignment and placement parameters in musculoskeletal applications based on said reference image and said operative image taken by said image capturing module with reference to a software generated virtual grid, wherein said software generated virtual grid provides a grid pattern aligned with at least one corresponding second anatomic marker in said operative image. a computer system, coupled to an x-ray emitter and an x-ray detector, wherein said x-ray detector is aligned to said x-ray emitter to capture an image of a patient; said computer system further comprising: i. an image capturing module configured to capture an operative image of a portion of said patient's body; and obtain a reference image of a contra lateral side of said portion of said patient's body; ii. a calibration and anatomical matching module coupled to said image capturing module and configured to 1. calibrate said reference image and said operative image to same magnification; 2. identify at least one first anatomic marker in said reference image and at least one corresponding second anatomic marker in said operative image; and 3. aligning said at least one second anatomic marker with said at least one first anatomic marker on an overlaid image; iii. a differential mapping module coupled to said calibration and anatomical matching module and configured to digitally quantify alignment and placement parameters in musculoskeletal applications based on said reference image and said operative image taken by said image capturing module with reference to a software generated virtual grid, wherein said software generated virtual grid provides a grid pattern aligned with at least one corresponding second anatomic marker in said operative image. i. an image capturing module configured to capture an operative image of a portion of said patient's body; and obtain a reference image of a contra lateral side of said portion of said patient's body; capture an operative image of a portion of said patient's body; and obtain a reference image of a contra lateral side of said portion of said patient's body; ii. a calibration and anatomical matching module coupled to said image capturing module and configured to 1. calibrate said reference image and said operative image to same magnification; 2. identify at least one first anatomic marker in said reference image and at least one corresponding second anatomic marker in said operative image; and 3. aligning said at least one second anatomic marker with said at least one first anatomic marker on an overlaid image; 1. calibrate said reference image and said operative image to same magnification; 2. identify at least one first anatomic marker in said reference image and at least one corresponding second anatomic marker in said operative image; and 3. aligning said at least one second anatomic marker with said at least one first anatomic marker on an overlaid image; iii. a differential mapping module coupled to said calibration and anatomical matching module and configured to digitally quantify alignment and placement parameters in musculoskeletal applications based on said reference image and said operative image taken by said image capturing module with reference to a software generated virtual grid,