A pressure sensitive adhesive sheet comprising, on a substrate or a release material, a resin layer that is a multilayer structure containing at least a layer (Xβ), a layer, and a layer (Xα) laminated in this order, at least a surface (α) of the layer (Xα) of the resin layer having pressure sensitive adhesiveness, wherein at least a constitutional component contained in the layer is different from a constitutional component contained in the layer (Xα) and a constitutional component contained in the layer (Xβ), wherein the resin layer contains a pressure sensitive adhesive resin, the layer (Xβ) contains one or more components selected from an acrylic resin, a urethane resin, a rubber resin and a silicone resin as the pressure sensitive adhesive resin, the layer contains an acrylic resin as the pressure sensitive adhesive resin, the layer (Xα) contains an acrylic resin as the pressure sensitive adhesive resin and a crosslinking agent, in at least one cross section of two cross sections of the pressure sensitive adhesive sheet resulting from freely-selecting a region surrounded by a square having an edge length of 5 mm on the surface (α) and cutting the region in the thickness direction with a plane surface going through each of two diagonal lines of the square and being perpendicular to the region on the surface (α), thicknesses of the layer (Xα) and the layer in a range of 250 μm in a horizontal direction freely-selected on the cross section satisfy the following requirements (Xα-I) and (Y1-I): requirement (Xα-I): a difference [H MAX (Xα)-H MIN (Xα)] between a maximum value (H MAX (Xα)) of the thickness of the layer (Xα) and a minimum value (H MIN (Xα)) of the thickness of the layer (Xα) is 3.00 μm or more, and requirement (Y1-I): a difference [H MAX -H MIN] between a maximum value (H MAX) of the thickness of the layer and a minimum value (H MIN) of the thickness of the layer is 5.00 μm or more. at least a constitutional component contained in the layer is different from a constitutional component contained in the layer (Xα) and a constitutional component contained in the layer (Xβ), wherein the resin layer contains a pressure sensitive adhesive resin, the layer (Xβ) contains one or more components selected from an acrylic resin, a urethane resin, a rubber resin and a silicone resin as the pressure sensitive adhesive resin, the layer contains an acrylic resin as the pressure sensitive adhesive resin, the layer (Xα) contains an acrylic resin as the pressure sensitive adhesive resin and a crosslinking agent, in at least one cross section of two cross sections of the pressure sensitive adhesive sheet resulting from freely-selecting a region surrounded by a square having an edge length of 5 mm on the surface (α) and cutting the region in the thickness direction with a plane surface going through each of two diagonal lines of the square and being perpendicular to the region on the surface (α), thicknesses of the layer (Xα) and the layer in a range of 250 μm in a horizontal direction freely-selected on the cross section satisfy the following requirements (Xα-I) and (Y1-I): requirement (Xα-I): a difference [H MAX (Xα)-H MIN (Xα)] between a maximum value (H MAX (Xα)) of the thickness of the layer (Xα) and a minimum value (H MIN (Xα)) of the thickness of the layer (Xα) is 3.00 μm or more, and requirement (Y1-I): a difference [H MAX -H MIN] between a maximum value (H MAX) of the thickness of the layer and a minimum value (H MIN) of the thickness of the layer is 5.00 μm or more. requirement (Xα-I): a difference [H MAX (Xα)-H MIN (Xα)] between a maximum value (H MAX (Xα)) of the thickness of the layer (Xα) and a minimum value (H MIN (Xα)) of the thickness of the layer (Xα) is 3.00 μm or more, and requirement (Y1-I): a difference [H MAX -H MIN] between a maximum value (H MAX) of the thickness of the layer and a minimum value (H MIN) of the thickness of the layer is 5.00 μm or more.