mhurhangee/ep-ind-claims huggingface dataset:
A virion comprising a nucleic acid comprising in 5' to 3' direction (i) an adeno-associated virus inverted terminal repeat sequence; (ii) a promoter selected from AAV promoters p5, p19 and p40, preferably p5 or p19, and even more preferably the combination of the p5 and the p19 promoter; (iii) at least one AAV rep gene coding sequence under the control of said promoter of (ii), wherein the at least one AAV rep gene coding sequence encodes the AAV Rep78 polypeptide of SEQ ID NO: 7 or a sequence being at least 80% identical thereto and/or the AAV Rep68 polypeptide of SEQ ID NO: 6 or a sequence being at least 80% identical thereto and being capable of performing replication, wherein preferably the at least one AAV rep gene coding sequence further encodes the AAV Rep52 polypeptide of SEQ ID NO: 9 or a sequence being at least 80% identical thereto and/or AAV Rep40 polypeptide of SEQ ID NO: 8 or a sequence being at least 80% identical thereto; (iv) a p40 promoter extending from position 1700 until position 2287 of the AAV2 genome according to GenBank entry NC_001401.2 or a sequence being at least 80% identical thereto while retaining the promoter activity; (v) a transgenic coding sequence under the control of said promoter of (iv); (vi) a polyadenylation site; and (vii) an adeno-associated virus inverted terminal repeat sequence; wherein said virion does not comprise an AAV cap gene and/or is not able to express any AAV cap gene products. (i) an adeno-associated virus inverted terminal repeat sequence; (ii) a promoter selected from AAV promoters p5, p19 and p40, preferably p5 or p19, and even more preferably the combination of the p5 and the p19 promoter; (iii) at least one AAV rep gene coding sequence under the control of said promoter of (ii), wherein the at least one AAV rep gene coding sequence encodes the AAV Rep78 polypeptide of SEQ ID NO: 7 or a sequence being at least 80% identical thereto and/or the AAV Rep68 polypeptide of SEQ ID NO: 6 or a sequence being at least 80% identical thereto and being capable of performing replication, wherein preferably the at least one AAV rep gene coding sequence further encodes the AAV Rep52 polypeptide of SEQ ID NO: 9 or a sequence being at least 80% identical thereto and/or AAV Rep40 polypeptide of SEQ ID NO: 8 or a sequence being at least 80% identical thereto; (iv) a p40 promoter extending from position 1700 until position 2287 of the AAV2 genome according to GenBank entry NC_001401.2 or a sequence being at least 80% identical thereto while retaining the promoter activity; (v) a transgenic coding sequence under the control of said promoter of (iv); (vi) a polyadenylation site; and (vii) an adeno-associated virus inverted terminal repeat sequence; wherein said virion does not comprise an AAV cap gene and/or is not able to express any AAV cap gene products.
A method for wireless communication at a user equipment, UE, comprising: receiving configuration information for at least a first sounding reference signal, SRS, resource set and a second SRS resource set, the first SRS resource set and the second SRS resource set each including two or more parameters for an associated SRS transmission; and characterised by: determining that the first SRS resource set and the second SRS resource set are mapped to a same transmission resource, wherein the transmission resource comprises two or more antenna ports used by an SRS transmission; selecting the first SRS resource set for a first SRS communication using the transmission resource based at least in part on a prioritization associated with each of the first SRS resource set and the second SRS resource set; and transmitting the first SRS communication based at least in part on one or more SRS transmission parameters associated with the first SRS resource set. determining that the first SRS resource set and the second SRS resource set are mapped to a same transmission resource, wherein the transmission resource comprises two or more antenna ports used by an SRS transmission; selecting the first SRS resource set for a first SRS communication using the transmission resource based at least in part on a prioritization associated with each of the first SRS resource set and the second SRS resource set; and transmitting the first SRS communication based at least in part on one or more SRS transmission parameters associated with the first SRS resource set.
A system for developing a radiotherapy treatment plan, the system comprising: a data storage device configured to hold magnetic resonance image data acquired using a magnetic resonance imaging system; at least one processor configured to: receive the MR image data from the data storage device, wherein the MR image data include temporal reshuffled k-space data, and wherein the MR image data comprises 4D MR image data; apply corrections to the 4D MR image data to produce a series of corrected image data; assemble the series of corrected image data to generate a set of relaxometry maps; perform a segmentation of a plurality of regions of interest using the set of relaxometry maps; classify the plurality of regions of interest, using the set of relaxometry maps, to yield a plurality of classified structures; assign electron density values to the classified structures using an assignment process; generate, using the electron density values of the classified structures, a set of corrected synthetic electron density images; and perform a dose calculation using the corrected synthetic electron density images to develop a radiotherapy treatment plan. a data storage device configured to hold magnetic resonance image data acquired using a magnetic resonance imaging system; at least one processor configured to: receive the MR image data from the data storage device, wherein the MR image data include temporal reshuffled k-space data, and wherein the MR image data comprises 4D MR image data; apply corrections to the 4D MR image data to produce a series of corrected image data; assemble the series of corrected image data to generate a set of relaxometry maps; perform a segmentation of a plurality of regions of interest using the set of relaxometry maps; classify the plurality of regions of interest, using the set of relaxometry maps, to yield a plurality of classified structures; assign electron density values to the classified structures using an assignment process; generate, using the electron density values of the classified structures, a set of corrected synthetic electron density images; and perform a dose calculation using the corrected synthetic electron density images to develop a radiotherapy treatment plan. receive the MR image data from the data storage device, wherein the MR image data include temporal reshuffled k-space data, and wherein the MR image data comprises 4D MR image data; apply corrections to the 4D MR image data to produce a series of corrected image data; assemble the series of corrected image data to generate a set of relaxometry maps; perform a segmentation of a plurality of regions of interest using the set of relaxometry maps; classify the plurality of regions of interest, using the set of relaxometry maps, to yield a plurality of classified structures; assign electron density values to the classified structures using an assignment process; generate, using the electron density values of the classified structures, a set of corrected synthetic electron density images; and perform a dose calculation using the corrected synthetic electron density images to develop a radiotherapy treatment plan.
A shelf ready package comprising at least one carton blank, formed into an outer case having: (a) a top wall, (b) two side walls and, (c) a front wall, (d) a back wall, wherein the shelf ready package is at least partially sealed using tape and the tape comprises tape perforations, characterised in that the shelf ready package further comprises an at least partially removable element, formed by a line of weakness, such that the at least partially removable element can be at least partially or fully removed along the line of weakness, wherein the tape overlaps with at least part of the line of weakness in the outer case, and the tape perforations coincide with at least part of the line of weakness of the outer case formed by the carton blank. (a) a top wall, (b) two side walls and, (c) a front wall, (d) a back wall,
A soluble form of a member of the CD83 family of proteins consisting of the extracellular domain of the CD83 protein with the amino acid residues 20 to 144 of SEQ ID NO:2 (sCD83 protein), a functional derivative of said sCD83 protein having up to 10 amino acids attached to the C- or N-terminus of said sCD83 protein and/or having up to 10 amino acids of said sCD83 protein substituted, a dimeric or trimeric form of said sCD83 protein, or a dimeric or trimeric form of the functional derivative of said sCD83 protein, for use in wound closure of cutaneous wounds.
A combination of a robotic garden tool and a charging device, the combination comprising a charging coupling for connecting the robotic garden tool to the charging device, the charging coupling comprising a first charging contact and a second charging contact, characterized in that the second charging contact comprises a row of at least two resilient contact bars for providing multiple contact points between the first charging contact and the second charging contact.
A continuous process for selectively modifying the lumen surface of a hollow fiber membrane having an inner diameter in the range of 5 to 700 μm, comprising the steps of continuously transporting the hollow fiber membrane through a zone ( 4,5,6) of reduced pressure having a negative pressure gradient and removing gas from the hollow fiber membrane; continuously transporting the hollow fiber membrane through a plasma ignition zone comprising a reactive gas, optionally admixed with a carrier gas, wherein the diameter d2 of the lumen of the hollow fiber membrane is larger than the distance d1 between the outer diameter of the hollow fiber membrane and the inner diameter of the plasma ignition zone; and wherein the pressure within the plasma ignition zone is higher than the minimum pressure in the zone ( 4,5,6) of reduced pressure having a negative pressure gradient and the zone ( 8,9,10) of reduced pressure having a positive pressure gradient, respectively; and using radio frequencies at a power output of 0.1 to 10 W to generate a plasma inside the lumen of the hollow fiber membrane within said plasma ignition zone, thereby generating functional groups exclusively on the lumen surface of the hollow fiber membrane; continuously transporting the hollow fiber membrane through a zone ( 8,9,10) of reduced pressure having a positive pressure gradient.
A method for determining user liveness comprising: capturing facial authentication data from a user as a video; calculating, by a processor, user mouth surface areas for frames of the facial authentication data and calculating a difference between sequential mouth surface areas; plotting the differences over time to generate a differential mouth surface area signal; extracting overlapping sectioned differential surface area signals (32, 34) from the differential mouth surface area signal; creating a principal component analysis coefficient set for each overlapping sectioned differential surface area signal (32, 34) by calculating Fast Fourier Transform, FFT, spectral coefficients for each overlapping sectioned differential surface area signal (32, 34), normalizing the FFT spectral coefficients, and projecting the normalized FFT spectral coefficients onto a pre-trained principal component analysis basis; selecting a principal component analysis coefficient subset from each set; classifying the principal component analysis coefficient subset by creating a vector for each subset and by inputting the vector into a pre-trained classifier to generate a binary result for each overlapping sectioned differential surface area signal; calculating a mouth activity score by aggregating the binary results and comparing the mouth activity score against a threshold score; and determining the user is live when the mouth activity score is equal to or greater than the threshold score. capturing facial authentication data from a user as a video; calculating, by a processor, user mouth surface areas for frames of the facial authentication data and calculating a difference between sequential mouth surface areas; plotting the differences over time to generate a differential mouth surface area signal; extracting overlapping sectioned differential surface area signals (32, 34) from the differential mouth surface area signal; creating a principal component analysis coefficient set for each overlapping sectioned differential surface area signal (32, 34) by calculating Fast Fourier Transform, FFT, spectral coefficients for each overlapping sectioned differential surface area signal (32, 34), normalizing the FFT spectral coefficients, and projecting the normalized FFT spectral coefficients onto a pre-trained principal component analysis basis; selecting a principal component analysis coefficient subset from each set; classifying the principal component analysis coefficient subset by creating a vector for each subset and by inputting the vector into a pre-trained classifier to generate a binary result for each overlapping sectioned differential surface area signal; calculating a mouth activity score by aggregating the binary results and comparing the mouth activity score against a threshold score; and determining the user is live when the mouth activity score is equal to or greater than the threshold score.
A clutch device, in particular a single or double clutch, having at least one counter-pressure plate, a pressure plate, which is displaceable in a limited manner relative to the counter-pressure plate in the axial direction of the clutch device, for frictionally engaged clamping of a clutch plate between the counter-pressure plate and the pressure plate, and a wear-adjustment device for compensating for wear on the clutch plate, wherein the wear adjustment-device has at least one rotatable drive ring which is clampable in the axial direction and at least one rotatable ramp ring which is clampable in an axial direction, characterised in that the ramp ring is connected to the drive ring by means of a torque-transferring connection allowing a limited relative path in the circumferential direction of the clutch device, wherein the rigidity of the connection in the circumferential direction is directionally dependent.
A road construction machine, configured as a road roller, with a front carriage and a rear carriage connected to one another via a pendulum/articulated joint, wherein a driver cab is arranged on said front carriage or on said rear carriage, wherein the front carriage has two lateral structural members to which two supports for the front drum are attached, and wherein a crossmember having lighting devices arranged thereon extends between the two structural members (8, 9), characterized in that the crossmember consists of a self-supporting hollow body made of plastic in which the lighting devices are integrated.
A toy construction element comprising a bowl shaped shell part having a peripheral rim surface, an inner face, a stand surface adapted for allowing the shell part to rest on a plane surface, and a first and a second type of protruding connecting parts (26, 27), and where the shell part is configured such that two identical shell parts can be assembled by interconnecting the first type of protruding connecting parts on each shell part to the second type of protruding connecting parts on the other shell part, and so that their peripheral rim surfaces are mutually facing each other to form a substantially closed capsule with the inner faces enclosing an inner volume, wherein the first type of protruding connecting part and the second type of protruding connecting part are positioned adjacent the peripheral rim surface at opposite sides, and where each of the first type of protruding connecting part and the second type of protruding connecting part are adapted to form a releasable and pivotable hinge connection with a hinge axis, and where the hinge axes defined by the first and the second type of protruding connecting parts (26, 27) are mutually parallel and defining a first plane, and where the stand surface extends in a second plane substantially perpendicular to the first plane, and where the peripheral rim surface extends in the first plane.
An applicator for gel products, in particular a toilet-cleaning product, comprising • a receiving space for a first gel product, wherein the receiving space comprises the first gel product and a movable piston; • a second receiving space for a second gel product that differs from the first gel product, wherein the second receiving space comprises the second gel product and a second movable piston; a piston holder for the two pistons (6a, 6b), wherein the piston holder is formed such that it comprises the receiving spaces (2a, 2b) on the outside thereof at least in portions; and wherein each receiving space (2a, 2b) comprises a first opening (4a, 4b) and a second opening (5a, 5b), the first opening (4a, 4b) being provided in order to release the gel product (3a, 3b) and the second opening (5a, 5b) being provided in order to receive the piston (6a, 6b) that is movable in the receiving space (2a, 2b), by means of which piston the gel product (3a, 3b) can be pushed through the first opening (4a, 4b); and wherein at least two, preferably at least three, spacer elements (7a, 7b, 7c, 7d, 7e, 7f) are arranged and configured on the applicator around each first opening (4a, 4b) in the relevant receiving space (2a, 2b) such that, when pressing the applicator against a toilet surface to which the gel product (3a, 3b) is to be applied and which is in particular ceramic, a distance A is formed between the first opening (4a, 4b) and the surface, and in each case the gel product (3a, 3b) can flow freely around the spacer elements (7a, 7b, 7c, 7d, 7e, 7f) when emerging; and wherein the applicator comprises resilient portion markers which are between the two receiving spaces (2a, 2b), are arranged so as to be in parallel with the direction of flow of the preparations (3a, 3b), project outwards, and abut a collar of the piston holder when the piston holder is pushed forward, such that, when the piston holder and the pistons (6a, 6b) are inserted into the receiving spaces (2a, 2b), slight resistance is generated when the relevant portion marker is reached, the relevant portion marker being pushed through the collar of the piston holder into the interior of one of the receiving spaces (2a, 2b) against the spring resistance, as a result of the spring mounting of the portion markers; wherein the portion markers are designed so as to be ramp-shaped or curved in the movement direction of the piston holder. • a receiving space for a first gel product, wherein the receiving space comprises the first gel product and a movable piston; • a second receiving space for a second gel product that differs from the first gel product, wherein the second receiving space comprises the second gel product and a second movable piston;
An intelligent controller (402; 802) comprising: a processor (502; 702); a memory; a control schedule (416; 706) stored in the memory; a schedule interface (410; 714); a control interface (411-413; 712); and instructions stored within the memory that, when executed by the processor, cause the processor to: receive immediate-control inputs through the control interface (411-413; 712) during a monitoring period and record the immediate-control inputs in the memory; receive schedule changes through the schedule interface (410; 714) during the monitoring period and record the schedule changes in the memory; generate an updated monitoring-period schedule, after the monitoring period, based on the immediate-control inputs, the schedule changes, and the control schedule (416; 706); substitute the updated monitoring-period schedule for a portion of the control schedule (416; 706) corresponding to the monitoring period; and propagate the updated monitoring-period schedule to additional time periods within the control schedule (416; 706). a processor (502; 702); a memory; a control schedule (416; 706) stored in the memory; a schedule interface (410; 714); a control interface (411-413; 712); and instructions stored within the memory that, when executed by the processor, cause the processor to: receive immediate-control inputs through the control interface (411-413; 712) during a monitoring period and record the immediate-control inputs in the memory; receive schedule changes through the schedule interface (410; 714) during the monitoring period and record the schedule changes in the memory; generate an updated monitoring-period schedule, after the monitoring period, based on the immediate-control inputs, the schedule changes, and the control schedule (416; 706); substitute the updated monitoring-period schedule for a portion of the control schedule (416; 706) corresponding to the monitoring period; and propagate the updated monitoring-period schedule to additional time periods within the control schedule (416; 706). receive immediate-control inputs through the control interface (411-413; 712) during a monitoring period and record the immediate-control inputs in the memory; receive schedule changes through the schedule interface (410; 714) during the monitoring period and record the schedule changes in the memory; generate an updated monitoring-period schedule, after the monitoring period, based on the immediate-control inputs, the schedule changes, and the control schedule (416; 706); substitute the updated monitoring-period schedule for a portion of the control schedule (416; 706) corresponding to the monitoring period; and propagate the updated monitoring-period schedule to additional time periods within the control schedule (416; 706).