An automated method for correcting an image of an imager of a reagent analyzer, comprising: - positioning a dry reagent pad (108a-n) at a first read position in a field of view of the imager, the first read position illuminated by an illumination source with a first intensity; - detecting a reference optical signal by the imager, the reference optical signal indicative of a first reflectance value of the dry reagent pad (108a-n) at the first read position; - positioning the dry reagent pad (108a-n) at a second read position in the field of view of the imager, the second read position illuminated with a second intensity, which - due to non-uniformity of the level of intensity of illumination across the field of view, is different from the first intensity - detecting a first optical signal by the imager, the first optical signal indicative of a second reflectance value of the dry reagent pad (108a-n) at the second read position; and - calculating, by a processor executing processor executable code, a calibration factor for the dry reagent pad (108a-n) at the second read position based on a difference between the reference optical signal and the first optical signal, - positioning a reagent (108a-n) having a volume of sample deposited thereon at the first read position; - capturing a second optical signal by the imager, the second optical signal indicative of a reflectance value of the reagent pad (108a-n) having a volume of sample deposited thereon at the first read position; - positioning the reagent pad (108a-n) having a volume of sample deposited thereor at the second read position; - capturing a third optical signal by the imager, the third optical signal indicative of a reflectance value of the reagent pad (108a-n) having a volume of sample deposited thereon at the second read position; and - determining, by the processor, a position-corrected reflectance value of the reagent pad (108a-n) having a volume of sample deposited thereon at the second read position by applying the calibration factor to the third optical signal; wherein a dry reagent pad (108a-n) is a reagent pad (108a-n) which does not have a volume of sample deposited thereon, or that does not have a sufficient amount of sample deposited thereon to react with the reagent. - positioning a dry reagent pad (108a-n) at a first read position in a field of view of the imager, the first read position illuminated by an illumination source with a first intensity; - detecting a reference optical signal by the imager, the reference optical signal indicative of a first reflectance value of the dry reagent pad (108a-n) at the first read position; - positioning the dry reagent pad (108a-n) at a second read position in the field of view of the imager, the second read position illuminated with a second intensity, which - due to non-uniformity of the level of intensity of illumination across the field of view, is different from the first intensity - detecting a first optical signal by the imager, the first optical signal indicative of a second reflectance value of the dry reagent pad (108a-n) at the second read position; and - calculating, by a processor executing processor executable code, a calibration factor for the dry reagent pad (108a-n) at the second read position based on a difference between the reference optical signal and the first optical signal, - positioning a reagent (108a-n) having a volume of sample deposited thereon at the first read position; - capturing a second optical signal by the imager, the second optical signal indicative of a reflectance value of the reagent pad (108a-n) having a volume of sample deposited thereon at the first read position; - positioning the reagent pad (108a-n) having a volume of sample deposited thereor at the second read position; - capturing a third optical signal by the imager, the third optical signal indicative of a reflectance value of the reagent pad (108a-n) having a volume of sample deposited thereon at the second read position; and - determining, by the processor, a position-corrected reflectance value of the reagent pad (108a-n) having a volume of sample deposited thereon at the second read position by applying the calibration factor to the third optical signal;