mhurhangee/ep-ind-claims huggingface dataset:
Process for the preparation of an antibody-conjugate, comprising reacting a modified antibody with a linker-conjugate, wherein said linker-conjugate comprises a (hetero)cycloalkynyl group and one or more molecules of interest, wherein said modified antibody is an antibody comprising a GlcNAc-S x substituent, wherein GlcNAc is an N-acetylglucosamine, wherein S x is a sugar derivative comprising x functional groups A wherein A is an azido group and x is 1, 2, 3 or 4, wherein said GlcNAc-S x substituent is bonded to the antibody via C1 of the N-acetylglucosamine of said GlcNAc-S x substituent, and wherein said GlcNAc is optionally fucosylated.
Method for calibrating and correcting scanning distortion of an optical coherence tomography system, comprising the following phases: i) selecting a reference pattern which comprises a number of known reference points which are described in a number of real coordinates; ii) acquiring images of the reference pattern selected in phase i), the reference pattern being located in an object space of the optical coherence tomography system, by means of the optical coherence tomography system; iii) identifying, in the images acquired of the reference pattern, a number of positions of a number of reference points described in a number of local coordinates provided by the optical coherence tomography system, which correspond to the reference points known in phase i); iv) obtaining a mathematical distortion relationship which defines a transformation between the local coordinates provided by the optical coherence tomography system and a number of real coordinates, the mathematical relationship being based on the comparison of the positions of the known reference points in the local coordinates of phase iii) and in the real coordinates in phase i); and, v) correcting the scanning distortion by means of applying the mathematical distortion relationship obtained in phase iv) to the data obtained by the optical coherence tomography system. i) selecting a reference pattern which comprises a number of known reference points which are described in a number of real coordinates; ii) acquiring images of the reference pattern selected in phase i), the reference pattern being located in an object space of the optical coherence tomography system, by means of the optical coherence tomography system; iii) identifying, in the images acquired of the reference pattern, a number of positions of a number of reference points described in a number of local coordinates provided by the optical coherence tomography system, which correspond to the reference points known in phase i); iv) obtaining a mathematical distortion relationship which defines a transformation between the local coordinates provided by the optical coherence tomography system and a number of real coordinates, the mathematical relationship being based on the comparison of the positions of the known reference points in the local coordinates of phase iii) and in the real coordinates in phase i); and, v) correcting the scanning distortion by means of applying the mathematical distortion relationship obtained in phase iv) to the data obtained by the optical coherence tomography system.
A mechanical joint for transferring rotational motion from a first shaft to a second shaft, comprising: a housing comprising an outer casing, a central cavity, a first end and a second end; a first groove comprising a first concave sliding contact surface including a straight portion, a second groove comprising a second concave sliding contact surface including a straight portion, the first and second grooves disposed on opposite sides of the central cavity; a first lip comprising a third contact surface at the first end of the housing, the first lip aligned with the first groove; a second lip comprising a fourth contact surface at the first end of the housing, the second lip aligned with the second groove; a drive puck comprising a circular outer perimeter, an outer contact surface, and an inner slot; a drive shaft comprising a first end and a second end, the first end pivotably coupled with the drive puck by a pin, the second end coupled with the first shaft; wherein the drive puck is disposed within the first and second grooves (535a, 535b) the outer contact surface slidingly engaged with the first and second concave sliding contact surfaces (536a, 536b) of the first and second grooves, respectively, the drive puck maintained within the first and second grooves at the first end of the housing by the third and fourth contact surfaces of the first and second lips; and wherein the drive puck rotates within the first and second grooves (535a, 535b) in a first plane and the drive shaft rotates about the pin in a second plane, the first plane being orthogonal to the second plane. a housing comprising an outer casing, a central cavity, a first end and a second end; a first groove comprising a first concave sliding contact surface including a straight portion, a second groove comprising a second concave sliding contact surface including a straight portion, the first and second grooves disposed on opposite sides of the central cavity; a first lip comprising a third contact surface at the first end of the housing, the first lip aligned with the first groove; a second lip comprising a fourth contact surface at the first end of the housing, the second lip aligned with the second groove; a drive puck comprising a circular outer perimeter, an outer contact surface, and an inner slot; a drive shaft comprising a first end and a second end, the first end pivotably coupled with the drive puck by a pin, the second end coupled with the first shaft; wherein the drive puck is disposed within the first and second grooves (535a, 535b) the outer contact surface slidingly engaged with the first and second concave sliding contact surfaces (536a, 536b) of the first and second grooves, respectively, the drive puck maintained within the first and second grooves at the first end of the housing by the third and fourth contact surfaces of the first and second lips; and wherein the drive puck rotates within the first and second grooves (535a, 535b) in a first plane and the drive shaft rotates about the pin in a second plane, the first plane being orthogonal to the second plane.
Compound selected from inhibitors of p75NTR receptor, alone or in association with at least one compound selected from TrkA receptor activators, or a compound selected from TrkA receptor activators, for use in anti-inflammatory treatment of the chronic inflammatory diseases of auto-inflammatory or autoimmune origin, with the exclusion of allergic origin diseases, in patients wherein the expression ratio TrkA receptor/p75NTR receptor is lower than 1 in inflamed tissues or cells of biological fluids; wherein the inhibitors of p75NTR receptor are selected from the group consisting of polyclonal and monoclonal monospecific or bispecific p75NTR receptor binding antibodies, chimerical molecules whose structure includes soluble p75NTR receptor, p75NTR receptor binding cyclic monomeric and dimeric NGF analogous compounds and wherein the TrkA receptor activators are selected from the group consisting of TrkA receptor binding polyclonal and monoclonal antibodies, cyclic monomeric and dimeric NGF analogous compound, recombinant NGF or recombinant mutated NGF.
A field panel for controlling a building automation system, comprising: a) a processor; and b) an input device of the building automation system, coupled to the processor, able to read a code displayed by a mobile device (406, 300), wherein the processor is configured to decode the code into data associated with building automation system and at least a first portion of the data is user identification data unique to the mobile device (406, 300) that generates the code; and c) a communication module coupled to the processor, wherein the communication module is adapted to transmit at least a second portion of the data associated with building automation to at least one environment system that makes up the building automation system, wherein the second portion of the data is environmental parameters associated with the building automation system set by a user. a) a processor; and b) an input device of the building automation system, coupled to the processor, able to read a code displayed by a mobile device (406, 300), wherein the processor is configured to decode the code into data associated with building automation system and at least a first portion of the data is user identification data unique to the mobile device (406, 300) that generates the code; and c) a communication module coupled to the processor, wherein the communication module is adapted to transmit at least a second portion of the data associated with building automation to at least one environment system that makes up the building automation system,
A sighting telescope mounting system for a firearm for mounting a sighting telescope onto the firearm in a desired position, wherein the firearm and/or the sighting telescope are aligned in the desired position in an axial direction, with a pivot foot which can be attached to the sighting telescope, and with a pivot holding device which can be affixed to the firearm, or vice versa, wherein the pivot foot and the pivot holding device together form a pivot joint, which during mounting enables a pivot of the sighting telescope by a pivot angle around a pivot range (M, 22) on a plane which is formed by the sighting telescope and the axial direction of the firearm, with a connection surface which is arranged on the pivot holding device and with a clamping surface which is arranged on the pivot foot, and which when mounted forms a contact area with the connection surface, so that the pivot foot is affixed, in particular clamped, in the axial direction, wherein in the desired position, the contact area is arranged in the radial alignment and/or towards the sighting telescope at a distance to an edge of the connection surface, characterized in that the pivoting force and/or the pre-tensioning force between the connection surface and the clamping surface is or are constant or virtually constant in a pivot angle range about the desired position.
A stable, taste-masked, ready-to-use suspension comprising crystalline rifaximin or a pharmaceutically acceptable salt, hydrate, solvate, or polymorph thereof dispersed in a suspension base and one or more pharmaceutically acceptable additive(s), wherein the viscosity of the suspension is from 20 to 200 Cps, when measured by Brookfield viscometer at room temperature and 100 RPM using spindle no. 2, and d 90 of the rifaximin is less than 40 μm, when measured using light scattering technique (Malvern Mastersizer Hydro 2000S), and further wherein the suspension is stable for 3 months under accelerated conditions (40°C/75%RH).
System for the preparation of foodstuffs provided according to a system for the presentation of foodstuffs, said system comprising a plurality of individual ready-to-prepare food blocks and/or contiguous food blocks, each consisting of at least one foodstuff and formed into a basic shape having at least one through-opening formed in the food block, wherein the system comprises a cooking device in the form of a heating device with a receptacle for one or a plurality of food blocks serving as a cooking receptacle, the receptacle comprising a thermally conductive support body with a support for at least one surface of a food block and a heating mandrel projecting at right angles from the support, which is dimensioned in such a way that it can be inserted into the through-opening, wherein the heating device is an active heating device with an integrated heating device or a passive heating device for insertion into an external cooking device and wherein the heating mandrel is adapted in its shape to the through-opening in the food block.
A method for detecting damage in a support means comprising at least one tension member for an elevator system, comprising the following steps: - generating at least one digital input signal by means of a pulse generator, wherein the digital input signal represents at least one first binary number, - feeding the digital input signal to the at least one tension member, - detecting a digital output signal after the digital input signal has passed through the at least one tension member, wherein the digital output signal represents at least one second binary number, - comparing, in particular comparing digit by digit, the second binary number with a binary setpoint binary number and/or directly with the first binary number, - reporting a fault state, when the second binary number differs from the setpoint binary number and/or from the first binary number. - generating at least one digital input signal by means of a pulse generator, wherein the digital input signal represents at least one first binary number, - feeding the digital input signal to the at least one tension member, - detecting a digital output signal after the digital input signal has passed through the at least one tension member, wherein the digital output signal represents at least one second binary number, - comparing, in particular comparing digit by digit, the second binary number with a binary setpoint binary number and/or directly with the first binary number, - reporting a fault state, when the second binary number differs from the setpoint binary number and/or from the first binary number.
An agent comprising anionic polyacrylate for use in a method of treating or ameliorating at least one symptom of a pregnancy related hypertensive disorder in a pregnant subject having elevated soluble Flt-1 (sFlt-1) levels or for use in a method of reducing elevated levels of sFlt-1 in blood, serum, or plasma of a pregnant subject having a pregnancy related hypertensive disorder, each said method comprising the step of extracorporeally removing sFlt-1 from blood, serum, or plasma from the pregnant subject, wherein said removing comprises an apheresis procedure, wherein said apheresis procedure comprises the use of anionic polyacrylate to bind said sFlt-1, wherein said apheresis procedure is sufficient to treat or ameliorate at least one symptom of a pregnancy related hypertensive disorder or wherein said apheresis procedure is sufficient to reduce the level of sFlt-1 in a subject in need thereof.
Antenna arrangement for a level transmitter designed to determine and monitor a level of a medium in a vessel using a microwave time-of-flight method, wherein said arrangement comprises a horn antenna with a horn-shaped component designed to concentrate the microwaves and a process separation element that is permeable to microwaves, said element being provided in the area of the outlet opening of the horn-shaped component facing towards the medium, and which separates the interior area of the horn-shaped component from the interior area of the vessel, wherein an extension component is provided for the further concentration of the microwaves, wherein said component extends the horn-shaped component in the radiation direction of the microwaves, wherein the process separation element is designed and arranged in such a way that the horn-shaped component and the extension component are galvanically isolated from one another, wherein the extension component has a horn-like design and has an opening angle that corresponds approximately to an opening angle of the horn-shaped component, characterized in that the extension component has an entrance opening that is smaller than the outlet opening of the horn-shaped component.
A through-substrate optical imaging device for through-imaging of translucent work objects including a radiation source outputting radiation that will be transmissive through the work object wherein the radiation source is configured such that the radiation impinges on the surface of the work object under various angles of incidence and/or orientations and an imaging system configured for capturing inspection information from the radiation source through the work object characterized in that said device comprises at least two radiation sources or radiation source points which are configured for simultaneously irradiating the work object from at least two locations, and wherein the radiation sources or radiation source points of the radiation sources are angularly positionable relative to the work object, such that in different angular positions of the radiation sources or the radiation source points the radiation impinges on the surface of the work object under different angles of incidence,
A diverter device for pulse jet cleaning comprising, a control valve configured for receiving pulse air from a pulse air manifold and controllably passing a pulse of pulse air downstream, and at least one diverter configured for receiving the pulse from the control valve and diverting the pulse into a plurality of outlet ports for providing pulse air to at least two blowpipes (124, 126) for cleaning a filter assembly, wherein the diverter further comprises, a housing defining a diverter chamber, the diverter chamber having a pulse air inlet and a plurality of pulse air outlets, a movable plug positioned in a first position within a first pulse air outlet, the plug defining an aperture for selectively controlling pulse air flow through the chamber and into one of the pulse air outlets, the plug movable between the first position and a second position within a second pulse air outlet, and at least one pilot line extending from the diverter to at least one of a first blowpipe and a second blowpipe, the pilot line configured to deliver a portion of the pulse to the diverter for passively moving the plug between the first and second position.
Applied-ignition internal combustion engine having at least one first combustion chamber and one second combustion chamber in which a fuel/air mixture can be combusted, wherein an exhaust-gas system is arranged at the combustion chambers, and wherein an exhaust gas from a combustion of the fuel/air mixture flows firstly through an exhaust-gas manifold and subsequently through an exhaust-gas purification system in the exhaust-gas system, wherein a first section of the exhaust-gas system from the first combustion chamber to the exhaust-gas purification system is better cooled than a second section of the exhaust-gas system from the second combustion chamber to the exhaust-gas purification system, characterized in that the first combustion chamber is operable with a lean (λ > 1) fuel/air mixture and the second combustion chamber is operable with a rich (λ < 1) fuel/air mixture, wherein an overall exhaust-gas lambda value at the inlet into the exhaust-gas purification system is stoichiometric (λ = 1).
A system comprising a device, a mount (200, 300, 400, 500, 600, 700), at least one first fastening element (160a, 160b) and at least one first fastening means (250a, 250b; 350a, 350b;...), wherein: (a) the device comprises a plurality of cooling fins (134a, 136a,...), wherein at least one first groove (110a, 110b) is formed between two of the cooling fins (134a, 136a,...), and the first fastening element (160a, 160b) is arranged in the first groove (110a, 110b); and (b) the first fastening means (250a, 250b; 350a, 350b;...) interacts with the first fastening element (160a, 160b) such that the mount (200, 300, 400, 500, 600, 700) is connected to the device, wherein the mount (200, 300, 400, 500, 600, 700) has a recess (220a, 220b), wherein the fastening means (250a, 250b) is mounted in the recess (220a, 220b), and characterized in that the fastening element (160a, 160b) and the groove (110a, 110b) are formed such that the fastening element (160a, 160b) is displaceable in the longitudinal direction of the groove (110a, 110b). (a) the device comprises a plurality of cooling fins (134a, 136a,...), wherein at least one first groove (110a, 110b) is formed between two of the cooling fins (134a, 136a,...), and the first fastening element (160a, 160b) is arranged in the first groove (110a, 110b); and (b) the first fastening means (250a, 250b; 350a, 350b;...) interacts with the first fastening element (160a, 160b) such that the mount (200, 300, 400, 500, 600, 700) is connected to the device, wherein the mount (200, 300, 400, 500, 600, 700) has a recess (220a, 220b), wherein the fastening means (250a, 250b) is mounted in the recess (220a, 220b), and characterized in that the fastening element (160a, 160b) and the groove (110a, 110b) are formed such that the fastening element (160a, 160b) is displaceable in the longitudinal direction of the groove (110a, 110b).
A method of controlling the concentration of a solution of a solid product and a liquid dispensed from a dispenser, comprising: providing a solid product in a dispenser; contacting the solid product with a pool of liquid, provided by liquid holding means, to produce a solution, wherein said holding means includes one or more walls connected to provide a basin where liquid can be introduced and used to provide erosion and dissolution of a solid product; measuring the concentration of the solution; and adjusting with one or more fluid directing geometries within the pool of liquid the liquid flow scheme within the pool of liquid based upon the measured concentration of the solution to provide a desired concentration of the solution; wherein controlling the liquid flow scheme within the pool of liquid controls how the water impinges on the surface or surfaces of the solid product that are in contact with the liquid. providing a solid product in a dispenser; contacting the solid product with a pool of liquid, provided by liquid holding means, to produce a solution, wherein said holding means includes one or more walls connected to provide a basin where liquid can be introduced and used to provide erosion and dissolution of a solid product; measuring the concentration of the solution; and adjusting with one or more fluid directing geometries within the pool of liquid the liquid flow scheme within the pool of liquid based upon the measured concentration of the solution to provide a desired concentration of the solution; wherein controlling the liquid flow scheme within the pool of liquid controls how the water impinges on the surface or surfaces of the solid product that are in contact with the liquid.
An electronic assembly casing having walls (11, 12, 13) providing an internal chamber and a circuit board mount to mount a circuit board in the internal chamber, the casing further comprising a heat sink cage in one of said walls to accommodate a heat sink of the circuit board when mounted on the circuit board mount, the heat sink cage being in a first wall of the casing that extends, when the circuit board is mounted, in a first plane substantially parallel to a surface of the circuit board mounting the heat sink, the first wall further defining a trench (11a-c) about said cage, the trench (11a-c) extending from said first plane toward said surface of said circuit board.
An aircraft turbine engine with a main axis A including: - an arm that is radial with respect to the main axis A and which extends throughout an air flow duct; - a support wall belonging to the radial arm and which includes two openings; - a plurality of harnesses partially extending throughout the radial arm and where a section of each harness is fastened to said support wall of the arm; characterised in that it includes two mounting blocks where each mounting block is associated with a group of sections of the harnesses. - an arm that is radial with respect to the main axis A and which extends throughout an air flow duct; - a support wall belonging to the radial arm and which includes two openings; - a plurality of harnesses partially extending throughout the radial arm and where a section of each harness is fastened to said support wall of the arm; characterised in that it includes two mounting blocks where each mounting block is associated with a group of sections of the harnesses.