A remote antenna unit (300, 400, 500) for use in a distributed antenna system, the remote antenna unit (300, 400, 500) comprising: a transport interface to communicatively couple the remote antenna unit (300, 400, 500) to a host unit included in the distributed antenna system and to receive a downstream transport signal from the host unit; a processing unit coupled to the transport interface; at least one downstream signal branch; at least one upstream signal branch; wherein the processing unit and downstream signal branch are configured to use the downstream transport signal to generate a downstream radio frequency signal for radiation from an antenna associated with the remote antenna unit (300, 400, 500); wherein the transport interface is configured to communicate an upstream transport signal from the remote antenna unit (300, 400, 500) to the host unit, wherein the processing unit and the upstream signal branch are configured to generate an upstream signal from a received upstream radio frequency signal received at the remote antenna unit (300, 400, 500), the upstream signal including a digital representation of the received upstream radio frequency signal, wherein the transport interface is further configured to use the upstream signal to generate the upstream transport signal; and wherein the downstream signal branch comprises a feedback path configured to digitize the downstream radio frequency signal to provide a digital representation of the downstream radio frequency signal radiated from the antenna to the processing unit; wherein the processing unit is configured to pre-distort an input signal to the downstream signal branch for non-linearities in the downstream signal branch using the digital representation of the downstream radio frequency signal radiated from the antenna as received from the feedback path; and wherein the processing unit is further configured to perform self-interference suppression processing on the upstream signal by digitally subtracting the digital representation of the downstream radio frequency signal radiated from the antenna, as received from the feedback path, from the digital representation of the received upstream radio frequency signal. a transport interface to communicatively couple the remote antenna unit (300, 400, 500) to a host unit included in the distributed antenna system and to receive a downstream transport signal from the host unit; a processing unit coupled to the transport interface; at least one downstream signal branch; at least one upstream signal branch; wherein the processing unit and downstream signal branch are configured to use the downstream transport signal to generate a downstream radio frequency signal for radiation from an antenna associated with the remote antenna unit (300, 400, 500); wherein the transport interface is configured to communicate an upstream transport signal from the remote antenna unit (300, 400, 500) to the host unit, wherein the processing unit and the upstream signal branch are configured to generate an upstream signal from a received upstream radio frequency signal received at the remote antenna unit (300, 400, 500), the upstream signal including a digital representation of the received upstream radio frequency signal, wherein the transport interface is further configured to use the upstream signal to generate the upstream transport signal; and wherein the downstream signal branch comprises a feedback path configured to digitize the downstream radio frequency signal to provide a digital representation of the downstream radio frequency signal radiated from the antenna to the processing unit; wherein the processing unit is configured to pre-distort an input signal to the downstream signal branch for non-linearities in the downstream signal branch using the digital representation of the downstream radio frequency signal radiated from the antenna as received from the feedback path; and wherein the processing unit is further configured to perform self-interference suppression processing on the upstream signal by digitally subtracting the digital representation of the downstream radio frequency signal radiated from the antenna, as received from the feedback path, from the digital representation of the received upstream radio frequency signal.